PharMolix/UniProtQA huggingface dataset:
Protein: GLYA_STRCO
Sequence: MSLLNTPLHELDPDVAAAVDAELDRQQSTLEMIASENFAPVAVMEAQGSVLTNKYAEGYPGRRYYGGCEHVDVVEQIAIDRVKALFGAEHANVQPHSGAQANAAAMFALLKPGDTIMGLNLAHGGHLTHGMKINFSGKLYNVVPYHVGDDGQVDMAEVERLAKETKPKLIVAGWSAYPRQLDFAAFRKVADEVGAYLMVDMAHFAGLVAAGLHPNPVPHAHVVTTTTHKTLGGPRGGVILSTAELAKKINSAVFPGQQGGPLEHVVAAKAVAFKVAASEDFKERQGRTLEGARILAERLVRDDAKAAGVSVLTGGTDVHLVLVDLRDSELDGQQAEDRLHEVGITVNRNAVPNDPRPPMVTSGLRIGTPALATRGFTAEDFAEVADVIAEALKPSYDAEALKARVKTLADKHPLYPGLNK
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAF_SYNEL
Sequence: MRRFLALLLVLTLWLGFTPLASADVAGLVPCKDSPAFQKRAAAAVNTTADPASGQKRFERYSQALCGEDGLPHLVVDGRLSRAGDFLIPSVLFLYIAGWIGWVGRAYLIAVRNSGEANEKEIIIDVPLAIKCMLTGFAWPLAALKELASGELTAKDNEITVSPR
What is the function of this protein?
Probably participates in efficiency of electron transfer from plastocyanin to P700 (or cytochrome c553 in algae and cyanobacteria).  This plastocyanin-docking protein contributes to the specific association of plastocyanin to PSI.
What are the official names of this protein?
Photosystem I reaction center subunit III, PSI-F.
What is the protein family that this protein belongs to?
Belongs to the PsaF family.
Protein: EFTU_RHOOB
Sequence: MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKVLHDAYPDLNEASAFDEIDKAPEEKARGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKADMVDDDEIIELVEMEVRELLAAQEFDEDAPVVKVSALKALEGDPEWTKNILELMAAVDESIPDPVRETEKPFLMPVEDVFTITGRGTVVTGRIERGVINVNEDVEIVGIKETKTKTTVTGIEMFRKLLDSGQAGDNVGLLVRGIKREDVERGQVVVKPGTTTPHTEFEGQAYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEGTEMVMPGDNTEMSVKLIQPVAMDEGLRFAIREGGRTVGAGKVTKINK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHK_OENAR
Sequence: MNSIEFTLLARRTQNSVISTTSNDLSNWSRLSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRSSPRQADLILTAGTVTMKMAPSLVRLYEQMPEPKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAIIDAITKLRKKISREIYEDRIRSQEENRCFTTNHKFHVGPSMHTGNYDPGLLYQLPSTSEIASETFFKYKSSVSAHELVN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: PDRP_BARBK
Sequence: MKKEKNFFHLYMVSDATGETLISAGKAVASQYPTIQPIEHIYPMIRNKTQLQRVLDEIQREPGIVLYTIIDQEIKQLLSRECTKIGVPCAAVLDPVLNVFQSYLGTPKNLRVSAQHDLNTDYFRRIEALDFTIEHDDGQSSDDLFNADVILVGISRTSKTPTSIYLANRGIKTANVPLIPGIDLPKALLEEKNSLIIGLIASAERISHVRQNRELGKDVSIERYTDRVNIAEELTYAKRICERFGWPIIDVTRRSIEETAAAVFELLSRFREEKLREIL
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: HXADB_TAKRU
Sequence: MTASVLLHSHWIDPVMFLYENGLDERNKNMEGFTGSNFPANQCRNLLAHPTSLAPNTTYTSNDVPISGIGEPGKQCSPCPATQSSPNASLPYGYFGSSYYPCRVSHGSVKACAQPSGYGDKYMDSPVSGEEFSSRAKEYAFYQGYSSAPYQPSYLDVPVVPALSAPSETRHEPLLPMEPYQPWTITNGWSGQVYCTKEQPQSNPLWKSSLQGNSGVRRGRKKRVPYTKVQLKELEREYAANKFITKDKRRRISAQTNLTERQVTIWFQNRRVKEKKVVNKFKSPS
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-A13b.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSEB_CAMJE
Sequence: MFNKKNILITGGTGSFGKTYTKVLLENYKPNKIIIYSRDELKQFEMASVFNAPCMRYFIGDVRDKERLSAAMRDVDFVIHAAAMKHVPIAEYNPMECIKTNIHGAQNVIDACFENGVKKCIALSTDKACNPVNLYGATKLASDKLFVAANNIAGNKQTRFGVTRYGNVVGSRGSVVPFFKKLISEGAKELPITDTRMTRFWISLEDGVKFVLSNFERMHGGEIFIPKIPSMKITDLAHALAPNLSHKIIGIRAGEKLHEIMISSDDSHLTYEFENYYAISPSIKFVDKDNDFSINALGEKGQKVKDGFSYSSDNNPLWASEKELLEIINHTEGF
What is the function of this protein?
Catalyzes the first step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin.  Has both C6 dehydratase and C5 epimerase activities that result in the production of both UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4-hexulose and UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-4-hexulose.
What are the official names of this protein?
UDP-N-acetylglucosamine 4,6-dehydratase (inverting), Pseudaminic acid biosynthesis protein B, UDP-GlcNAc-inverting 4,6-dehydratase.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide synthase family.
Protein: LHA2_CERSP
Sequence: MTNGKIWLVVKPTVGVPLFLSAAVIASVVIHAAVLTTTTWLPAYYQGSAAVAAE
What is the function of this protein?
Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
What are the official names of this protein?
Light-harvesting protein B-800/850 alpha chain, Antenna pigment protein alpha chain, LH-2.
What is the protein family that this protein belongs to?
Belongs to the antenna complex alpha subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: SYH_ONYPE
Sequence: MFSKIKGTYDLMSDKMVCWQKVENHIRTLFAKYHLQEIRTPIIEYRGVFDRAAQHSEMVSKETYTFADKKERFITLRPEGTAGVIRSYVENKLDKTSQLHKFFYYGPCFRYERPQKGRYRQFHQVGVEILGQSNPFLDVEVIALAYETIKSLGICDITVKINSLGCKTTYNNYLQVFKNYLQAHYQQLCPLCQERFEKNILRIWDCKNCNNEPFLKQAPRIFDHLVEDAKVRFLQVLEGLKQMNVNFELCHDLVRGLDYYTHSVFEIVYNNEQGHQAVLGGGGCYDNLVTLFGGNPSPGIGFALGMERLMSILATHSFCNKNILPSLDAFILVSVPQFFYQGLALATTLRHQGFSADLNYQFLSFSKSLKQALKQQPLYLLILGPKEFDNNQITIKNTDTQQQTTILQKDVVSYFQNNKELN
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE23_HELFE
Sequence: MKLTPKELDKLMLHYAGRLAEEALARGVKLNYTEAVALISGRVMEKARDGNKSVADLMQEGRTWLKKENVMDGVASMIHEVGIEANFPDGTKLVTIHTPVEDNGKLAPGEVFLKNEDITINAGKEAISLKVKNKGDRPVQVGSHFHFFEVNKLLDFDRAKSFCKRLDIASGTAVRFEPGEEKSVELIDIGGNKRIYGFNSLVDRQADADGKKLGLKRAKEKGFGSVNCGCEATKDKQ
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORF10_BPKPP
Sequence: MAGRTSTYAPNQVTIVINHAASGISHTLTGFSEDSIVSVERLVDTFTEYVGADDTHTRVFNANSGARATVSLAQTSESNDVLTFLHEFDREAMSADGMFEMLIKDNSGRSLYFSDEAYIAVIPQGGFSNQMNTRDWVISMTNTTFQHGGNQKVSPATADTLTALGVNLDARWL
What are the official names of this protein?
Structural protein ORF10.
What are the subcellular locations of this protein?
Virion.
Protein: HBT1_YEAST
Sequence: MNMNESISKDGQGEEEQNNFSFGGKPGSYDSNSDSAQRKKSFSTTKPTEYNLPKEQPESTSKNLETKAKNILLPWRKKHNKDSETPHEDTEADANRRANVTSDVNPVSADTKSSSGPNATITTHGYSYVKTTTPAATSEQSKVKTSPPTSHEHSNIKASPTAHRHSKGDAGHPSIATTHNHSTSKAATSPVTHTHGHSSATTSPVTHTHGHASVKTTSPTNTHEHSKANTGPSATATTHGHINVKTTHPVSHGHSGSSTGPKSTAAAQDHSSTKTNPSVTHGHTSVKDNSSATKGYSNTDSNSDRDVIPGSFRGMTGTDVNPVDPSVYTSTGPKSNVSSGMNAVDPSVYTDTSSKSADRRKYSGNTATGPPQDTIKEIAQNVKMDESEQTGLKNDQVSGSDAIQQQTMEPEPKAAVGTSGFVSQQPSYHDSNKNIQHPEKNKVDNKNISERAAEKFNIERDDILESADDYQQKNIKSKTDSNWGPIEYSSSAGKNKNLQDVVIPSSMKEKFDSGTSGSQNMPKAGTELGHMKYNDNGRDNLQYVAGSQAGSQNTNNNIDMSPRHEAEWSGLSNDATTRNNVVSPAMKDEDMNEDSTKPHQYGLDYLDDVEDYHENDIDDYSNAKKNDLYSKKAYQGKPSDYNYEQREKIPGTFEPDTLSKSVQKQDEDPLSPRQTTNRAGMETARDESLGNYEYSNTSGNKKLSDLSKNKSGPTPTRSNFIDQIEPRRAKTTQDIASDAKDFTNNPETGTTGNVDTTGRMGAKSKTFSSNPFDDSKNTDTHLENANVAAFDNSRSGDTTYSKSGDAETAAYDNIKNADPTYAKSQDITGMTHDQEPSSEQKASYGSGGNSQNQEYSSDDNIDVNKNAKVLEEDAPGYKREVDLKNKRRTDLGGADASNAYAAEVGNFPSLIDPHVPTYGFKDTNTSSSQKPSEGTYPETTSYSIHNETTSQGRKVSVGSMGSGKSKHHHNHHRHSRQNSSKGSDYDYNNSTHSAEHTPRHHQYGSDEGEQDYHDDEQGEEQAGKQSFMGRVRKSISGGTFGFRSEI
What is the function of this protein?
Polarity-determining protein which forms a conjugate with the ubiquitin-like modifier HUB1.  Involved in bud site selection and cellular morphogenesis during conjugation.  Required for survival during stationary phase.
What are the official names of this protein?
Protein HBT1, HUB1 target protein 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNF39_HUMAN
Sequence: MWWRDLTRLRLWLKREAIPGEGRKAAKVNAGVGEKGIYTASSRGGPPSARSKAVTVVAEGAASRSWLSMDAPELGPGLVERLEQLATCPLCGGSFEDPVLLACEHSFCRACLARRWGTPPATGTEASPTACPCCGLPCPRRSLRSNVRLAVEVRISRELREKLAEPGARAGRRRGGRIPTMGCLDLPGEDMRKTWRRFEVPTSKSSNSEDDLPEDYPVVKKMLHRLTADLTLDPGTAHRRLLISADRRSVQLAPPGTPAPPDGPKRFDQLPAVLGAQGFGAGRHCWEVETADAASCRDSSGEDADDEESHYAVGAAGESVQRKGCVRLCPAGAVWAVEGRGGRLWALTAPEPTLLGGVEPPPRRIRVDLDWERGRVAFYDGRSLDLLYAFQAPGPLGERIFPLFCTCDPRAPLRIVPAES
What is the function of this protein?
May play a role in prolonged long term-potentiation (LTP) maintenance.
What are the official names of this protein?
RING finger protein 39, Protein HZFw.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VAPB4_PYRFU
Sequence: MVKTITVSDDVYNELLRIKGKKSFSELLRELLREKKGNSVALKHIYGILNGEEYRETRKRLKELEKEFEKWKQFLTQV
What is the function of this protein?
Possibly the antitoxin component of a type II toxin-antitoxin (TA) system.  Its cognate toxin is VapC4 (Potential).
What are the official names of this protein?
Putative antitoxin VapB4.
What is the protein family that this protein belongs to?
Belongs to the UPF0330 family.
Protein: YQGF_BIFLO
Sequence: MVWLGVDLGNARVGLALSDPELTFAHPAGNIHVAGDYFFAIDEVLNVIEDEHVDHVIVGLPLQMDGTEGKSAKKARRWAANLEKRLQAESEDSDSTEYQIPQVSLIDERLTTVSAHRQLFEAHKASNKHRPVVDQQSAVVILQTALDRTREQ
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSN9_HUMAN
Sequence: MARGCLCCLKYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFATFSPSFPSLSAANLVIAIGTIVMVTGFLGCLGAIKENKCLLLSFFIVLLVILLAELILLILFFVYMDKVNENAKKDLKEGLLLYHTENNVGLKNAWNIIQAEMRCCGVTDYTDWYPVLGENTVPDRCCMENSQGCGRNATTPLWRTGCYEKVKMWFDDNKHVLGTVGMCILIMQILGMAFSMTLFQHIHRTGKKYDA
What are the official names of this protein?
Tetraspanin-9, Tspan-9, Tetraspan NET-5.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
Protein: YHI9_YEAST
Sequence: MTLMVPFKQVDVFTEKPFMGNPVAVINFLEIDENEVSQEELQAIANWTNLSETTFLFKPSDKKYDYKLRIFTPRSELPFAGHPTIGSCKAFLEFTKNTTATSLVQECKIGAVPITINEGLISFKAPMADYESISSEMIADYEKAIGLKFIKPPALLHTGPEWIVALVEDAETCFNANPNFAMLAHQTKQNDHVGIILAGPKKEAAIKNSYEMRAFAPVINVYEDPVCGSGSVALARYLQEVYKFEKTTDITISEGGRLKRNGLMLASIKKEADNSTSYYIAGHATTVIDGKIKV
What are the official names of this protein?
Uncharacterized isomerase YHI9.
What is the protein family that this protein belongs to?
Belongs to the PhzF family.
Protein: CYSE_STAAC
Sequence: MLKRMRDDIKMVFEQDPAARSTLEVITTYAGLHAVWSHLIAHKLYNQKKYVAARAISQISRFFTGIEIHPGAKIGKRLFIDHGMGVVIGETCTIGDNVTIYQGVTLGGTGKERGKRHPDIGDNVLIAAGAKVLGNIKINSNVNIGANSVVLQSVPSYSTVVGIPGHIVKQDGVRVGKTFDHRHLPDPIYEQIKHLERQLEKTRNGEIQDDYII
What are the official names of this protein?
Serine acetyltransferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR1_DICDI
Sequence: MENNNNNFIEEEEELSEPKEKCGVFAIYAPELDVSRIAFFGLVALQHRGQESCGIATYDEFQSVHVETGMGLVNQVFNETNLKPLKGKMAIGHTRYSTAGKSTLVNAQPVIVQTLHGQIGIVQNGNLTTAKSLRKELMQKGVGFFIDSDVEVITQLLSNNPEGCDPHKPNWENRIAHFMSKAEAAYALCLMTPNGIYGVRDSLGMRPLCLGSLEVPCKDDPTKTITRYVLTSESCAIGTIGAKFIRDVRPGEIVHINENGITSFIGRSPSDNPALCVFEYVYFSRPDSSMEGQLIHIVRQRMGETLARESPPPQTCSNNDTIVIGVPDSSLPAAIGYAKQSGIPFTEGLTKNRYIHRTFIQPSDHLRQQGIKLKFNPLTENIQGKKVILVDDSIVRANTIKALIKLIRGAGATEIHVRISSPPVLHPCHMGIDMATYDQLIGHNRTVEEIREYIGAESLQYLTLEGLMKSVNIGIKPQAETNSTPCFSTSSPTTTKIKINENNQKHCVACFTGDYPCSLDF
What are the official names of this protein?
Amidophosphoribosyltransferase, ATase, Glutamine phosphoribosylpyrophosphate amidotransferase, GPAT.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
Protein: PHOSP_CHAV
Sequence: MEDSQLYQALKNYPKLQDTLDSIENLEDDTKSEPSECGSPTERGIPSYYLAEELDECEEEDSEEDDDNLPTEIPDPPTVDMLEAIMEDEIDDTAYQVHFEAKQTWKPVIETGGNERGKFTLSVPQNLSALQLLQWETGIHALAERLGGCRLLQISTRGTRDGIEFTVRETPCVSPASDPIPSTSRSSSIASNVSTRQTESPGSKSNTSLGIPEAPANLIDMGAIDKEFILAAISPSDPPYKNTLRNLFGSGDSFEQYNQTGIYSLKELVIAGLKRKGIYNRIRIRCHLEPQFN
What is the function of this protein?
Essential component of the RNA polymerase transcription and replication complex.  Binds the viral ribonucleocapsid and positions the L polymerase on the template.  May act as a chaperone for newly synthesized free N protein, so-called N(0).  Plays a role in virion assembly (By similarity).
What are the official names of this protein?
Phosphoprotein, Protein P, Protein M1.
What is the protein family that this protein belongs to?
Belongs to the vesiculovirus protein P family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: M1290_ARATH
Sequence: MTFVPTDFLIRTPDDPAYFKDRLASPFSFRGCSKTTSTSSSIYSKKKASTATYFRVDPVPRGSQSSRVCEPKTKLIVYQPGNYQKKVKRQVTDPLSLMDKVKKRIDKTEIL
What are the official names of this protein?
Uncharacterized mitochondrial protein AtMg01290, ORF111c.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: THIL_RHOBA
Sequence: MEQSFLAYLRGRTRQLPQVAVGIGDDAAVIDWPGSVSSDQPQLRQVACTDQILDGVDFRSEEQSLSDIGFKAMAINLSDIAAMGATPSSALVTLALPAENATEIAGEVYEGILEAAQKYQVAIAGGDLSTYDGPLSISITILGWTEQPWLRTGAEEGDALFVTGALGGSLLGRHLRPEPRVELAAKLKQTVNVHAAIDVSDGFSLDLDRMLAASRMGAELELETLPISEAAHQFAEKSGRTPLEHAWSDGEDFELIFCVAPEEAAIIESTDWGVPVTRVGKVVGRTGLWKRVATSKFERVFPQGFVHGETDVAAAN
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
What are the official names of this protein?
Thiamine-monophosphate kinase, TMP kinase, Thiamine-phosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-monophosphate kinase family.
Protein: BSAA_STAAW
Sequence: METIYDFVVETNKGVTYKLDAYKGDVMLIVNTASECGFTSQFEGLQSLYEKYKDQGFVILGFPCNQFGGQEPGSGEEAAQNCKLNYGVTFPMHQKIDVKGEHQLPLFRYLTAAQHGFFNEKIKWNFTKFLVDREGNVVKRFAPQKKPVQIEREIEKLL
What are the official names of this protein?
Glutathione peroxidase homolog BsaA.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
Protein: CH60_ACET2
Sequence: MAKQIKFGEEARRALERGVNQLADTVKVTLGPKGRNVVLDKKFGSPMITNDGVTIAKEIELEDPFENMGAQLVKEVATKTNDVAGDGTTTATLLAQAIIREGLKNVAAGANPMLLKKGIAKAVDAAVEGIKEISQKVKGKEDIARVASISANDEVIGELIADAMEKVTNDGVITVEEAKTMGTNLEIVEGMQFDRGYVSPYMVTDTEKMEAVLDEPYILITDKKISNIQDILPLLEQIVQQGKKLVIIAEDVEGEALATLLVNKLRGTFTCVAVKAPGFGDRRKAMLEDIAILTGGQVITSDLGLELKDTTVEQLGRARQVKVQKENTIIVDGAGDPKEIQKRIASIKSQIEETTSDFDREKLQERLAKLAGGVAVIQVGAATETEMKEKKLRIEDALAATKAAVEEGIVAGGGTALVNVIPKVAKVLDTVSGDEKTGVQIILRALEEPVRQIAENAGLEGSVIVEKVKASEPGIGFDAYNEKYVNMIEAGIVDPAKVTRSALQNAASVASMVLTTESVVADIPEKETSGGPGGAGMGGMY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL12B_MACMU
Sequence: MCHQQLVISWFSLVFLASPLMAIWELKKDVYVVELDWYPDAPGEMVVLTCDTPEEDGITWTLDQSGEVLGSGKTLTIQVKEFGDAGQYTCHKGGEALSHSLLLLHKKEDGIWSTDVLKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDLTFSVKSSRGSSNPQGVTCGAVTLSAERVRGDNKEYEYSVECQEDSACPAAEERLPIEVMVDAIHKLKYENYTSSFFIRDIIKPDPPKNLQLKPLKNSRQVEVSWEYPDTWSTPHSYFSLTFCIQVQGKSKREKKDRIFTDKTSATVICRKNASFSVQAQDRYYSSSWSEWASVPCS
What is the function of this protein?
Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity.  IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues.  IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines.  IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis (By similarity).
What are the official names of this protein?
Interleukin-12 subunit beta, IL-12B, Cytotoxic lymphocyte maturation factor 40 kDa subunit, CLMF p40, IL-12 subunit p40.
What is the protein family that this protein belongs to?
Belongs to the IL-12B family.
What are the subcellular locations of this protein?
Secreted.
Protein: BLAF_MYCFO
Sequence: MTGLSRRNVLIGSLVAAAAVGAGVGGAAPAFAAPIDDQLAELERRDNVLIGLYAANLQSGRRITHRLDEMFAMCSTFKGYAAARVLQMAEHGEISLDNRVFVDADALVPNSPVTEARAGAEMTLAELCQAALQRSDNTAANLLLKTIGGPAAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTAAALAVGYRAILAGDALSPPQRGLLEDWMRANQTSSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRSQAHDPKAENLRPLIGELTALVLPSLL
What are the official names of this protein?
Beta-lactamase, Penicillinase.
What is the protein family that this protein belongs to?
Belongs to the class-A beta-lactamase family.
Protein: MNHG1_STAAW
Sequence: MIKIILISLALIFVIIGALISALAAIGLLRLEDVYSRAHAAGKASTLGAMSLLFGTFLYFIATQGFVNMQLIVAIIFVLITGPLSSHMIMKAAYNIKTPYTKKTKVDEISEDLKDTKL
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit G1, Mnh complex subunit G1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PHKG2_HUMAN
Sequence: MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAERLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQPWNLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYGHWVKKGEQQNRAALFQHRPPGPFPIMGPEEEGDSAAITEDEAVLVLG
What is the function of this protein?
Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase.  May regulate glycogeneolysis in the testis.  In vitro, phosphorylates PYGM (By similarity).
What are the official names of this protein?
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform, PHK-gamma-LT, PHK-gamma-T, PSK-C3, Phosphorylase kinase subunit gamma-2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Protein: SYI_LACLA
Sequence: MKIKDTLNLGKTAFPMRAGLPNKEPNWQKDWADATLYEKRQELNEGKPSFMLHDGPPYANGNIHLGHSLNKISKDIIVRYKSMAGFRAPYVPGWDTHGLPIEQQLAKAGMKRKEMDLLDYLEECRKYAMKQVDMQRSDFKSLGVLADWDRPYLTLLPEYEAAQIRVFGKMAEKGYIYKGQKPIYWSPSSESSLAEAEIEYQDVRSASIFVAFKAKDTKGKLPEDVEFVIWTTTPWTIPSNLGIFAHPDYDYSVVAVNGRKFVIASEMLEAVAEKLEWENPEVLQTIKGSELEYMVAKHPFYDRETLIMNADYVTLDSGTGLVHVAPGHGEDDYFASRKYKLPVLSPIDNRGYYTDEAPGLEGLLYDEGNKVVSKWLEEKDALLKLEFFTHSYPHDWRTKKPVIFRATPQWFASIDDFRQNILDEVERVDWVIPWGKTRLFNMVRDRGDWVISRQRAWGVPLPIFYGENGEPIITPETTEHVAKLFAEFGSKVWFEREAKDLLPEGFTHPASPNGEFTKEKDIMDVWFDSGSSWNGVLNERDYLSFPADLYLEGSDQYRGWFNSSITTSVAVNGVAPYKAVLSQGFVLDGKGRKMSKSIGNTIVPKDVTKKFGADILRLWVASIDTESDVRVSMDILSQVSEVYRKIRNTLRFLIANTSDFNPKEDAIDFAELRPVDKYMLVKFNELVKQIRTAYDNYSFMTVYKSIINFITNDLSSFYLDFAKDVVYIEAANSPERRSMQTVMYVILKDLVKILVPILPHTAEETWTYLEHEPENFAYLAEMPEAAEIPGSEELLGNWQEFLDFRDKILKALESAREAKLIGKSLEATVTIYPNEVVRTLLTAIDENVAQLLIVSNFVVANEPVNNAPESAMKFDDLAVLVEHAAGEVCDRCRRTDETVGHNANEHLKMLCEHCAHIVETEFPEILEEGFED
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CG121_PYRAB
Sequence: MTPKFKNFKHDNSGQVETYLFEVISKYTMLEIKTKFGKLCIAKVKLASESIERALNLCNDNCQIVSAKCHEEVIFATILAIKAFSSGRNTAKTIKGEILLRLAGVKQIKDAIKIIGARKGENLIIYFGVSDPCSSLKDFISSLGLREEPLKPCDEDEVKRGFERAAIIEAL
What is the function of this protein?
Component of the KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  Cgi121 acts as an allosteric effector that regulates the t(6)A activity of the complex.  Cgi121 is not required for tRNA modification.
What are the official names of this protein?
KEOPS complex subunit Cgi121.
What is the protein family that this protein belongs to?
Belongs to the CGI121/TPRKB family.
What are the subcellular locations of this protein?
Cytoplasm.