PharMolix/UniProtQA huggingface dataset:
Protein: RL21_AQUAE
Sequence: MYAVIKTGGKQYKVEKGMKLKVEKLPYEVGQTVEFEALMLRKDDGSIEFNKGKVIAEVKAHGRGKKLIVFKYRPKKNYKRWKGHRQPYTEIEIKDILP
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: LIPP_ICTTR
Sequence: MLLVWSLALLLGAVAGKEVCYDRLGCFSDDSPWSGIVERPLKVLPWSPADVNTRFLLYTNENQDNYQQITADSSRIQSSNFKTNRKTRFIIHGFIDKGEESWLANMCKKMFQVESVNCICVDWKGGSRTGYTQASQNIRIVGAEVAYFVDFLRTQLGYSPSNVHVIGHSLGSHAAGEAGRRTNGAIGRITGLDPAEPCFEGTPELVRLDPSDAQFVDAIHTDGAPIVPNLGFGMSQTVGHLDFFPNGGIEMPGCQKNILSQIVDIDGIWEGTRDFAACNHLRSYKYYTDSIVNPTGFAAFSCASYSVFSANKCFPCPSGGCPQMGHYADRYSGKTNGVGQKFYLNTGDKSNFSRWRYKVSVTLSGQKVTGHILVSLFGNAGNSKQYEIYKGSLHPGYTHSNEFDSDVDVGDLQRVKFIWYNNVINPSLPRVGASSISVERNDGRVFKFCSAETVREDVLLTLNAC
What is the function of this protein?
Plays an important role in fat metabolism.  It preferentially splits the esters of long-chain fatty acids at positions 1 and 3, producing mainly 2-monoacylglycerol and free fatty acids, and shows considerably higher activity against insoluble emulsified substrates than against soluble ones (By similarity).  Plays a role in hibernation as a key enzyme that shows high activity at low temperatures.  When expressed in the hibernating heart it liberates fatty acids from triglycerides at temperatures as low as 0 degrees Celsius.
What are the official names of this protein?
Pancreatic triacylglycerol lipase, PL, PTL, Pancreatic lipase, Heart pancreatic lipase, PL-h.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS9_XYLFA
Sequence: MPITQNYGTGRRKSSKARIFLRKGSGNITVNGRPLDEFFGRETARMIVRQPLELTKNVANFDILITATGGGTTGQAGAIRLGIARALVEYDASLKPELRKAGFMTRDAREVERKKVGLHKARRATQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: ATIF1_XENTR
Sequence: MAGSSSLLRAGIRNVLLMQMRRSSDQLGELGKGAGKGGGGGGSVREAGGAFGKRQAAEEERYFRQKEQEQIASLRKHHEEEIRHHKGEIERLQKEIERHKSKIKKLNDD
What is the function of this protein?
Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix.  Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase (By similarity).  Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme (By similarity).
What are the official names of this protein?
ATPase inhibitor, mitochondrial, ATP synthase F1 subunit epsilon, Inhibitor of F(1)F(o)-ATPase, IF(1), IF1.
What is the protein family that this protein belongs to?
Belongs to the ATPase inhibitor family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RNY_PSELT
Sequence: MIILVAVVTAVISFGLGYVVAKSRIEQKNRKAQQDAVSLLKKAEQEAQEIKRKAIIEAREEVHKIKEEIEEEKKRRDLEHRSLEERLLKREEIISKREELVDKKETALEQLRVQLEAAKKKIEQREKELDERFTKLAGMTVEEARQIVIDEARQKYEHDLAILYKKIKENYEEEAEKEAKKIIATAVQRYAPEYIGEITVSTVSLPSDDMKGRIIGREGRNIRTFEKITGVDLIIDDTPEVVVLSSFNPIRREIARLTLEKLVTDGRIHPARIEEMYEKSKQEMEKMIKEAGQEATFVTGVTGLHPELIKLLGKLKFRTSYGQNVLDHSIEVAQLAALMAEELGLDVDRTRRGGLLHDIGKALDHEVEGSHTEIGAEIARRYGESDHIINMIMSHHGEQEPVCPESVLVAAADALSAARPGARRESLETYIRRLVKMEKIAMSFKNVEKAYAIQAGREVRVIVEPEKIDDVEADKMAYEIAKKIEEEVEYPGVLKVVVIREKRSIAYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RL23_STAAC
Sequence: MEARDILKRPVITEKSSEAMAEDKYTFDVDTRVNKTQVKMAVEEIFNVKVASVNIMNYKPKKKRMGRYQGYTNKRRKAIVTLKEGSIDLFN
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: GBGT1_HUMAN
Sequence: MHRRRLALGLGFCLLAGTSLSVLWVYLENWLPVSYVPYYLPCPEIFNMKLHYKREKPLQPVVWSQYPQPKLLEHRPTQLLTLTPWLAPIVSEGTFNPELLQHIYQPLNLTIGVTVFAVGKYTHFIQSFLESAEEFFMRGYRVHYYIFTDNPAAVPGVPLGPHRLLSSIPIQGHSHWEETSMRRMETISQHIAKRAHREVDYLFCLDVDMVFRNPWGPETLGDLVAAIHPSYYAVPRQQFPYERRRVSTAFVADSEGDFYYGGAVFGGQVARVYEFTRGCHMAILADKANGIMAAWREESHLNRHFISNKPSKVLSPEYLWDDRKPQPPSLKLIRFSTLDKDISCLRS
What is the function of this protein?
Has lost the ability to synthesize Forssman glycolipid antigen (FORS1/FG) (PubMed:10506200).  Might have acquired an alternative function in glycosphingolipid metabolism, but it remains to be established.  It appears to have drifted more slowly than confirmed pseudogenes in the glycosyltransferase 6 family, suggesting that it has remained under evolutionary pressure.
What are the official names of this protein?
Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, Forssman glycolipid synthase-like protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 6 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: PA_I73A5
Sequence: MEDFVRQCFNPMVVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIVVELDDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSENTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMANRGLWDSFRQSERGEETIEERFEITGTMRRLADQSLPPNFSCLENFRAYVDGFEPNGCIEGKLSQMSKEVNAKIEPFLKTTPRPIKLPDGPPCFQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMRTFFGWKEPYIVKPHEKGINPNYLLSWKQVLAELQDIENEEKIPRTKNMKKTSQLKWALGENMAPEKVDFDNCRDISDLRQYDSDEPELRSLSSWIQNEFNKACELTDSIWIELDEIGEDVAPIEYIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRSAIGQMSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLVVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALR
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: ARGC_SYNY3
Sequence: MGNEKARVGIIGASGYGGIQLVRLLLEHPQVELTYLAGHSSAGKPYSDLYPHLTHRVNLTIEPIDLEAIASRCDAVFLGLPNGLACDMAPALLAKGCKVLDLSADYRFRNLNTYTEWYKKDRQDQATNNQAVYGLPELYRDAIRDAQLIGCPGCYPTASLLALSPLLKQGFIVPETAIIDAKSGTSGGGREAKVNMLLAEAEGSLGAYGVAKHRHTPEIEQIASDLAGTELRVQFTPHLIPMVRGILATVYATLRDPGLVRDDLITIYSAFYRASPFVKILPHGVYPQTKWAWGTNLCYIGIEVDPRTGRVIVLSAIDNLVKGQAGQAVQCLNLMMGWEESLGLPQLAFYP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RXFP1_MOUSE
Sequence: MTSGPFFFCIFIIGKYFTLGSAQDVSCPLGSFPCGNMSRCLPQLLHCNGVDDCGNRADEDHCGDNNGWSLQLDKYFANYYKLASTNSFEAETSECLVGSVPMHCLCRDLELDCDEANLRAVPSVSSNVTVMSLQRNFIRTLPPNGFRKYHELQKLCLQNNRIHSVSVSAFRGLRSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPLTFYGLNSLILLVLMNNALTRLPDKPLCQHMPRLHWLDFEGNRIHNLRNLTFISCNNLTVLVMRKNKINYLNEHAFTHLQKLDELDLGSNKIENLPPNIFKDLKELSQLNISYNPIQKIEVNQFDCLAKLKSLSLEGIEISNIQQRMFRPLINLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLENLLASIIQRVFVWVVSAITCFGNIFVICMRPYIRSENKLHAMSIISLCCADCLMGVYLFVIGAFDLKFRGEYNKHAQPWMESVHCQFMGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCLRPRKCRTITVLIFIWIIGFIVAFAPLGNKEFFKNYYGTNGVCFPLHSEDTGSTGAQIYSVVIFLGINLVAFIIIVFSYGSMFYSVHQSSVTVTEIQKQVKKEVVLAKRFFFIVFTDALCWIPIFILKFLSLLQVEIPDSITSWVVIFILPINSALNPIIYTLTTRPFKEMIHQLWHNYRQRRSVDRKETQKAYAPSFIWVEMWPLQEMSSGFMKPGAFTDPCDLSLVSQSSRLNSYS
What is the function of this protein?
Receptor for relaxins.  The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP.  Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.
What are the official names of this protein?
Relaxin receptor 1, Leucine-rich repeat-containing G-protein coupled receptor 7, Relaxin family peptide receptor 1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSMJ_ALISL
Sequence: MQIALLCEDLNRQSELEAIATRWGLTHDEDNVFALVLTTQQLELRKRDEPKLGAIFVDLVSGAVAHRRKFGGGKGQSIAKAVGLNKGATPLVLDGTAGLGRDAFVLASLGCKVQMVERHPVVAALLDDGLSRAKHDADIGGWVSQRMSLLHASSHDALEQLMAQDDFVQPDVVYLDPMYPHPENKKKSALVKKEMRVFQSLVGADNDADALLAPALLMATKRVVVKRPDYAEWLDNQKPSMAIETKKNRFDVYVNAGMKS
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQP4_CAEEL
Sequence: MSDENGPSKVDLQTAMRKMRALPPNKLCFDCGARNPTWCTVTYGVFLCIDCSAVHRNLGVHLTFVRSTNLDTNWTWLQLRAMQLGGNGNANQFFKAHGCNTTEAQQKYKSRAAQMYRDKLSTLCQEAQRKFGTQLIIDTVTHAEEKPAEEEDFFAQDFGHTSASATSLSSDAYIADHKSEDSTHGPSVDHLDSSVAVPTSAPVSVILKKPIKKATLGAKKNALGAQKVRINFDEIEQRAAEKERQTAAEVAANKLAYQTELDGKKKSDDAAALQKLSAKFAMQDIDAQRKQMEAKVAKDPTKAASVDRLGMGGVGRSRAAHSVAGGIRSIKQDDVLTFKKPSQPKEDDDWEVIDDKYGKKSTNNEDDFFSKDYTSSSSKKTTKEDDFFDSFETQPVQKSRYTASSSSSSTSRAPTTRLTAGASPISDVDLQKKFGNAKAISSDMYFGTPEMDCETRSALTKCEGQTSFGSEDLWGNGSQQRQSSQVPDMSDLKDSFRAGASKVAEKWSTLSSSFSTYMSRAPPATGEKT
What is the function of this protein?
GTPase-activating protein for the ADP ribosylation factor family.
What are the official names of this protein?
Uncharacterized protein F07F6.4.
Protein: ALG8_DICDI
Sequence: MIKKNNNSNNNNNNPIIIKDGTNCFFKEIKDVLKFSRNWNLIILVSTIKLLLIPSYLSTDFEVHRNWLAITSSLPISKWYFENTSEWTLDYPPFFGWFEYFLSKFAYYIDSEMLVIDNLGYKSTSTILFQRFSVIISDSLFILSTLLLSNYIYNIIIKKNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNLHWYHDKSFIISSIIILNPGLLMVDHIHFQYNGFLKGILILSIYFLVRGNILIGSILFSVLLNFKHIYMYMAPAFFVYLLKYYCLKSNLNDNTTSKVNHSKQQQQQEFTIFGIKIFNLIKLGISVLSIFLISLGPFFYMGQIQQLISRLFPFGRGLSHAYWAPNFWSIYNFLDRVLLFNGLYKKIPFFKNFIIPDQVTGNLTSGLVGSETQSHILLPKITPQITLLITILFLIPSIYSILKSKSWKHFILGICQSSFTFFMFGWHVHEKAIIMITIPMGFLCLVNNKFSKLYFLLSTIGHYSLFPLLFQVEEIPTRILILVTYTLLVYLSFISSSSNNNNNNNNNNNNSNNNNSKQRKCSFSLGLYWFEKFYLFGIILLEIFNVFIHPVFLAHIERFSFISLMITSVYTSVGIIYCYLFTFKLIFKNEY
What is the function of this protein?
Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation.  Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol (By similarity).
What are the official names of this protein?
Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase, Asparagine-linked glycosylation protein 8 homolog, Dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase, Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the ALG6/ALG8 glucosyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SDAC_HAEIN
Sequence: MKSTEKLKWNKFDATWMLNLFGTAVGAGVLFLPINAGMGGFWPLVLMAIIVGPMTYFAHRGLAYFVLSSKNPGSDITEVVEEHFGKTAGKLITLLYFFAIFPILLIYGNGITNTVDSFIVNQLGMASPNRVILSFVLIAVLISVMLFNEKVMLKITEWLVYPLVLILFVLSIYLIPEWNSAVLYEFPTVGGFLTTLWLTIPVLVFSFNHSPAISSFTCSQFREYKTFDGAERHISHTEKGASTILLFFVMFFVFSCVLTLTPEELVAAKEQNISILSFLANKFDNPYISYFGPLVAFLAITSSFFGHYMGAREGLEGLYLKMKGEAVNRKKLNYATALFFLLTLWGVAIINPSILGLIESLGGPIIAMILFIMPMYAIRKIPAMKRYSGRFSNVFVTIMGLIAISAVVYGLL
What is the function of this protein?
Mediates the import of L-serine into the cell.  Is energized by proton cotransport.
What are the official names of this protein?
Serine transporter SdaC, H(+)/L-serine symporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SECY_DIALT
Sequence: MKKAFVLEGPLVLRLFRTIMILIFARLGNYIPIPGITEVESFYESSFRNTSIYNLSALSGGSNVISILTLGLGPFFSASLAVQFLVKLYPAFEKLQNEEGEEGRKTIVRYTRILTVLFCIIESFFLSNSLRSFVFNWNSISYFVVAAAVTTGSLVLVWLSEVITERGIGNGSSLLILIGNLSRFRFLINKDDFDSLNVSSQSNLYIIYIIITLVSMLIFSTLSQEGARKIPVVSAKQLIDGVEDDMRRSYIPIRFGQAGVVPIIFSSSILLFLTTSIKQLPNANIATRVILDSVNLQQIFYFFTFLVLIIFFSFFYTLIILSPSDIAKNLKKMSSVIQDTKPGVATKVYIRKFILQASFVGSILLSALILIPSILAAALGVHPLSISGITSLILSFSIINDTVRQVLAYRDTRKFLLSS
What is the function of this protein?
The central subunit of the protein translocation channel SecYE.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NMDA1_DROSI
Sequence: MAVAGFVFCRPLFGLAIVLLVAPIDAAQRHTASDNPSTYNIGGVLSNSDSEEHFSTTIKHLNFDQQYVPRKVTYYDKTIRMDKNPIKTVFNVCDKLIENRVYAVVVSHEQTSGDLSPAAVSYTSGFYSIPVIGISSRDAAFSDKNIHVSFLRTVPPYYHQADVWLEMLSHFAYTKVIIIHSSDTDGRAILGRFQTTSQTYYDDVDVRATVELIVEFEPKLESFTEHLIDMKTAQSRVYLMYASTEDAQVIFRDAGEYNMTGEGHVWIVTEQALFSNNTPDGVLGLQLEHAHSDKGHIRDSVYVLASAIKEMISNETIAEAPKDCGDSAVNWESGKRLFQYLKSRNITGETGQVAFDDNGDRIYAGYDVINIREQQKKHVVGKFSYDSMRAKMRMRINDSEIIWPGKQRRKPEGIMIPTHLKLLTIEEKPFVYVRRMGDDEFRCEPDERPCPLFNNSDATANEFCCRGYCIDLLIELSKRINFTYDLALSPDGQFGHYILRNSTGAMTLRKEWTGLIGELVNERADMIVAPLTINPERAEYIEFSKPFKYQGITILEKKPSRSSTLVSFLQPFSNTLWILVMVSVHVVALVLYLLDRFSPFGRFKLSHSDSNEEKALNLSSAVWFAWGVLLNSGIGEGTPRSFSARVLGMVWAGFAMIIVASYTANLAAFLVLERPKTKLSGINDARLRNTMENLTCATVKGSSVDMYFRRQVELSNMYRTMEANNYATAEQAIQDVKKGKLMAFIWDSSRLEYEASKDCELVTAGELFGRSGYGIGLQKGSPWTDAVTLAILEFHESGFMEKLDKQWIFHGHVQQNCELFEKTPNTLGLKNMAGVFILVGVGIAGGVGLIIIEVIYKKHQVKKQKRLDIARHAADKWRGTIEKRKTIRASLAMQRQYNVGLNSTHAPGTISLAVDKRRYPRLGQRLGPERAWPGDAADVLRIRRPYELGKPGQSPKVMAANQPGMPMPMLGKTRPQQSVLPPRYSPGYTSDVSHLVV
What is the function of this protein?
NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium.  Mediated by glycine.  This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning.  It mediates neuronal functions in glutamate neurotransmission.  Is involved in the cell surface targeting of NMDA receptors.  Plays a role in associative learning and in long-term memory consolidation (By similarity).
What are the official names of this protein?
Glutamate [NMDA] receptor subunit 1.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane. Postsynaptic density.
Protein: NU2C1_VITVI
Sequence: MIWHIQNENFILDSTRIFMKAFHLLLFDGSFIFPECILIFGLILLLMIDSTSDQKDIPWLYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKKDVRSNEATTKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNGGYASMITYMLFYISMNLGTFACIVSFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVSIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYIRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: LCOR_HUMAN
Sequence: MQRMIQQFAAEYTSKNSSTQDPSQPNSTKNQSLPKASPVTTSPTAATTQNPVLSKLLMADQDSPLDLTVRKSQSEPSEQDGVLDLSTKKSPCAGSTSLSHSPGCSSTQGNGRPGRPSQYRPDGLRSGDGVPPRSLQDGTREGFGHSTSLKVPLARSLQISEELLSRNQLSTAASLGPSGLQNHGQHLILSREASWAKPHYEFNLSRMKFRGNGALSNISDLPFLAENSAFPKMALQAKQDGKKDVSHSSPVDLKIPQVRGMDLSWESRTGDQYSYSSLVMGSQTESALSKKLRAILPKQSRKSMLDAGPDSWGSDAEQSTSGQPYPTSDQEGDPGSKQPRKKRGRYRQYNSEILEEAISVVMSGKMSVSKAQSIYGIPHSTLEYKVKERLGTLKNPPKKKMKLMRSEGPDVSVKIELDPQGEAAQSANESKNE
What is the function of this protein?
May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3' (By similarity).  Repressor of ligand-dependent transcription activation by target nuclear receptors.  Repressor of ligand-dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR.
What are the official names of this protein?
Ligand-dependent corepressor, LCoR, Mblk1-related protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: FOLD_PROM2
Sequence: MSLKLDGKKLSLEIEERLNNYISSNKKIAKRAPGLAVIRIGEDPASGVYVNNKEKACSRIGIKSFIFHLKDSVEQKEVEQLIIKLNSDKDIDGILLQLPIPKKFDEQKLISSINPGKDVDGLNEINIGKLVKNEPAMRSCTPAGIINLLRSQNITIEGKKIVVIGRSLLVGKPLSLMLLNLNGTVTMTHSKTLNLNKVCREADILIAAAGKPNLVDSTFVKEGAVIIDVGIHRLKSSNKNQTRLCGDVLLEDVISKVFAYTPVPGGVGPMTVTMLLVNTIFSWQKQFGLSSTLNDLLP
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: ACUC_ASPA1
Sequence: MQPIVWLLGGAIALLVVVIRAAWTYGHRNQDMPSGPPTLPFIGNAHLIPKSYTHIQFTAWARQYGGLYMLKVGNSNMAVVTDRRIVKEVLDSKSSLYSHRPHSFVSHELITQGDHLLVMHYGPKWRTFRRLVHQHLMESMVDSQHLPIVNAEAIQLVRDYMLDPEHHMAHPKRFSNSITNSIVFGIRTADRHGSNMNRLYTLMEQWSEIMETGATPPVDIFPWLKRLPEALFGHYVTRARAIGAQMETLYEDILQRVEKRRSGGVHLDTFMDRVIASQDRNQLPRHQLAFIGGVLMEGGSDTSSSLTLAIVQALTLHPEVQRKAHAEIDAVVGHARSPVWDDLARLPYINMIIKEGHRWRPILPLCFPHALGQDDWVDGKFLPKGTMVVVNTWGMHMDPDHRLNQKYDPAKFVPERFAEHPALAPEYVPGAWENRDHYGYGVSRRICPGIHLAERNMFLAIAKLLWAFEFQPGPEGEPCDSDPVTGYQHGFLYCAKPYSTRPVLRSESIRETVEREFALAQREVFSTFTEG
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of aculins (PubMed:26374386).  The pathway begins with the synthesis of 6-methylsalicylic acid by the polyketide synthase (PKS) acuA via condensation of acetate and malonate units (PubMed:26374386).  The 6-methylsalicylic acid decarboxylase acuB then catalyzes the decarboxylation of 6-methylsalicylic acid to yield m-cresol (also known as 3-methylphenol) (Probable).  These first reactions occur in the cytosol (By similarity).  The intermediate m-cresol is then transported into the endoplasmic reticulum where the cytochrome P450 monooxygenase acuC converts it to m-hydroxybenzyl alcohol, which is further converted to gentisyl alcohol by the cytochrome P450 monooxygenase acuD (Probable).  Gentisyl alcohol is further oxidized by the oxidoreductase acuE that probably catalyzes hydroxylation of the aromatic ring (Probable).  The aromatic system might then be opened by oxidation through a Baeyer-Villiger type of oxidation, which could be catalyzed by acuF, with the carboxylic acid at C-1 subsequently reduced to an aldehyde by acuG (Probable).  Subsequently, a hemiacetal is formed, before the dehydrogenase acuH would reduce the double bond between C-4 and C-6 (Probable).  Finally, keto-enol tautomerism results in formation of aculinic acid, which exists as two diastereomers (both R/S configurations at C-1) by non-enzymatic hemiacetal formation (Probable).  The carboxypeptidase acuI could be involved in the linking of aculinic acid to an aculene A moiety produced by the aculene biosynthesis cluster and which leads to the production of aculin A (Probable).  AcuI may also be involved in the attachment of proline to aculinic acid to form epi-aculins A and B (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase acuC, Aculin biosynthesis cluster protein C, m-cresol hydrolase acuC.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.