PharMolix/UniProtQA huggingface dataset:
Protein: RBFA_CLOB1
Sequence: MAKYRAGRINEEVKKEVSNIIHNDIKDPRLSAMVSVTDVNVTKDLKYAKVYVSIFGNEKAKEESLEALKSSVGFIRKEVGRRVKLRNTPEVIIEVDNSIERGMHIDELLHSIKENESNDN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBH_TETOB
Sequence: MATGTTSKAKSSLSDALQEPGIVTPLGTLLRPLNSESGKVLPGWGTTVLMGVFIVLFAVFLLIILEIYNSSLLLDDVTMSWETLAS
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H, Photosystem II 10 kDa phosphoprotein.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: COFG_TRIV2
Sequence: MTVAESTCALVSTQPSIGKPTGGIATYSPAYTIVPTYECFNRCTYCNFRTDPGESSWMSLSAAEDIFKRLQNEQVCEILILSGEVHPNSPKRQVWFQRIYDLCKLALTLGFLPHTNAGPLSFAEMQELKSVNVSMGLMLEQLTPKLLETVHRHAPSKLPELRLQQLEWAGELQIPFTTGLLLGIGETNDDCWETLEAISKLHQRYHHIQEVILQPHSPGNQQTFNAPAFNPHQLPEVIAKARQILPSDITIQIPPNLVKDERWLLACVEAGARDLGGIGPKDEVNPDYPHLQAEELREILQPAGWDLMPRLPVYPQFDGWLSGELQASVRRWRELVIGNW
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil.
What are the official names of this protein?
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, FO synthase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofG family.
Protein: PNC1_ARATH
Sequence: MGVDLESVSEATSGAIGSLLSTTILYPLDTCKSKFQAEVRARGQQKYRYLSDVMWEAISKGQVFSLYQGLGTKNFQSFISQFIYFYSYSYFKRVHSERTGSKSIGTKANLLIAAAAGACTSVLIQPLDTASSRMQTSEFGESKGLWKTLTEGSWADAFDGLGISLLLTSNPAIQYTVFDQLKQHLLKQKNAKAENGSSPVVLSAFMAFVLGAVSKSVATVLTYPAIRCKVMIQAADESKENETKKPRRRTRKTIPGVVYAIWRKEGMLGFFKGLQAQILKTVLSSALLLMIKEKITATTWILILAIRRTLFLTNTKGKLRSP
What is the function of this protein?
Peroxisomal adenine nucleotide transporter catalyzing the counterexchange of ATP with AMP.  ATP is needed by reactions that generate acyl-CoA for peroxisomal fatty acid beta-oxidation during postgerminative growth.  Required for the beta-oxidation reactions involved in auxin biosynthesis and for the conversion of seed-reserved triacylglycerols into sucrose that is necessary for growth before the onset of photosynthesis.
What are the official names of this protein?
Peroxisomal adenine nucleotide carrier 1, AtPNC1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: ATPA1_LISMF
Sequence: MKTIHFDMNKYETHVDLEYLKEHGRVEKISDGVIFCSGLENAALHQAVLIDERHRGVILELNEEFVGIGLIDKTNDILEGMHVGVSGKFIEVDLFEEMAGRVIDTTGKMLYEESEEKPTATSPLFCVTPAIMTIDSVTRPLNTGLAVIDSITPIGRGQRQLILGNRQSGKTQIAVDTIINQHDQNVHCIYVAIGLKAAYIAEVIETLRNHGAMEYSTVVATAASDSLTAQYLTPYAGMAVAEALRDQGKDVLIILDDLTKHADAYRAITLLFNRPPGREAYPGDSFYIHSSLLERAVQMNEEHGGGSITAIPMIETLSDDVTAYIPTNVISITDGQLFLKSDLFNRGQKPAVDVGVSVSRIGGDAQHPIIRKLSKNLTLILSQFEELKELLDFGNALDDGSMKMVSDGRLLTELFKQKILSPLSVTELIVILYAFQNGFLTKIPPANIQTFKDLLLEKAHMHKDFESFSAQIETINELNESHIEMLEEIIREAGRLFS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha 1, ATP synthase F1 sector subunit alpha 1, F-ATPase subunit alpha 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SLT11_ASHGO
Sequence: MDEETPSICEQCLTDADLRMTRAARGAECKICTLPFTLYHFKPPGAPRVTKTLVCRRCAAQRNVCQCCMLDLAWKLPVALRDELVSLVQGSDERTPEASNEMVRRFLALRGGQLGGARLTADSAPLRELMGKMRAVAAAAAPAARAHGGREDAGEVPETQLPFGGALATPASRSFFIYGVDPALPEWELVDAVSQLVRTPDWRDAGSVSVVVRQDARCAGIRFRREELAQAFVARLETLPAAAGAPKGVLRIRHLRMHVVAWPEFHLAAFGETKQQTEGIARLATKTMRADAEGASPARPAAPASAAGKVAKKAAAPRRQGRRGPRPTLEL
What is the function of this protein?
Involved in pre-mRNA splicing.  Facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome.  Binds to RNA (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing factor SLT11.
What is the protein family that this protein belongs to?
Belongs to the SLT11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL24_SALPA
Sequence: MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKKHQKPVPALNQPGGIVEKEAAIQVSNVAIFNTATGKADRVGFRFEDGKKVRFFKSNSETIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: ATG4_BOTFB
Sequence: MTAADLGRYKRFVQYFWDPEPTNDTASQSPIWCLGKEYPILEKSATSAITDSPPQEGHYLPAQSLPTNEVTTPPDSTVGSLESSSGSQNCDTANADGGWPSAFLDDFEAKIWLTYRSNFPAIAKSQDPKALSAMSLSVRLRSQLVDQGGFTSDTGWGCMIRSGQSLLANALLTLRMGREWRRGVSSNEERKILSLFADDPRAPYSIHKFVEHGASACGKHPGEWFGPSATARCIQALSNSQAKSELRVYITGDGSDVYEDKFMSIAKPNHSDFTPTLILVGTRLGLDKITPVYWEALKYSLQMPQSVGIAGGRPSSSHYFIGVQESDFFYLDPHQTRPALPYKDNVEDYTTEDIDSCHTRRLRRLHIKEMDPSMLIAFLIRDENDWNEWRRAVKEVQGKGVIHVADTDPASYGLGGERDGAIDEVETFDDDDDDTILDA
What is the function of this protein?
Cysteine protease that plays a key role in cytoplasm to vacuole transport (Cvt) and autophagy by mediating both proteolytic activation and delipidation of ATG8.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  The protease activity is required for proteolytic activation of ATG8: cleaves the C-terminal amino acid of ATG8 to reveal a C-terminal glycine.  ATG8 ubiquitin-like activity requires the exposure of the glycine at the C-terminus for its conjugation to phosphatidylethanolamine (PE) and its insertion to membranes, which is necessary for autophagy.  The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.  In addition to the protease activity, also catalyzes deconjugation of PE-conjugated forms of ATG8 during macroautophagy: ATG8 delipidation is required to release the protein from membranes, which facilitates multiple events during macroautophagy, and especially for efficient autophagosome biogenesis, the assembly of ATG9-containing tubulovesicular clusters into phagophores/autophagosomes, and for the disassembly of PAS-associated ATG components.  ATG8 delipidation by ATG4 also recycles ATG8-PE generated on inappropriate membranes to maintain a reservoir of unlipidated ATG8 that is required for autophagosome formation at the PAS.
What are the official names of this protein?
Probable cysteine protease atg4, Autophagy-related protein 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase C54 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Preautophagosomal structure.
Protein: DDL_VIBVU
Sequence: MMRNVLLLCGGGSSEHEISLLSSEYLQQQLGLIENVNVLKVEIKNEGWFDQKERLVYLDIHTKSVKSDEFNESIHIDFIVPCIHGFPGETGDIQSLFELAGIPYLGCGPEASSNSFNKITSKLWYDAIGIPNTPYLFLTENNEESHQLSREAFDKWGKLFVKAARQGSSVGCYSVTKIEQLSDAIDKAFGFSHQVLVEKAVKPRELEVSAYEMNGQLHISKPGEIIAPDGAFYSYDEKYSAGSHSITEVEAKNLTEQQLATIQLCSEKVFRQMNLRHLSRIDFFLTSEGEIYLNEVNTFPGMTKISMFPKMLQHNGHKFHEFLADCIERSL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_HELMI
Sequence: MARYTGPVCRLCRREGAKLYLKGERCYTGKCAVDRRTYAPGQHGQGRKKISEYGLQLREKQKARRVYGILEGQFRAYFAEADRQQGVTGENLLRLLETRLDNVVFRLGFARSRNEARQFVLHNHFTLNGKKVNIPSIQLRVGDVIQLKEKSKDTPLFKEIVDGLGQKTPPAWLELDVNTLSGRVIALPKREDIDTNLQEHLIVELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: KPRB_CHICK
Sequence: MFCVPSTETGAIMNITKGGLVLFSANSNSSCMELSKRIAERLGVEMGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQCKMRKRGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIPDYRNAVIVAKSPASAKRAQSFAERLRLGIAVIHGEAQDAESDMVDGRHSPPTAKNVAAIHRSLEIPMLIPKEKPPITVVGDVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIFVMATHGLLSSDAPRLIEESAIDEVVVTNTIPHEIQKLQCPKIKTVDISMILSEAIRRIHNGESMSYLFRNIGLDD
What is the function of this protein?
Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis.
What are the official names of this protein?
Phosphoribosyl pyrophosphate synthase-associated protein 2, PRPP synthase-associated protein 2.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family.
Protein: NUDC_ECO81
Sequence: MDRIIEKLDHGWWVVSHEQKLWLPKGELPYGEAANFDLVGQRALQIGEWQGEPVWLVQLQRRHDMGSVRQVIDLDVGLFQLAGRGVQLAEFYRSHKYCGYCGHEMYPSKTEWAMLCSHCRERYYPQIAPCIIVAIRRDDSILLAQHTRHRNGVHTVLAGFVEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGEIVIDPKELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYE
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: O16EA_CONEA
Sequence: VLIIAVLFLTACQLTTAETYSRGRQKHRARRSTDKNSKWTRECTDSGGACNSHDQCCNEFCSTATRTCI
What are the official names of this protein?
Conotoxin Eb6.14.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOCD_RHOP5
Sequence: MSGAELISDLRARFGQAVLSEQSTNDAFPTLWIAPDAAPAVHRYLKHDVAKPFALLADLWAIDETARKHREGQPPSGITIASHLISLGRNADIVLKCPLDAKAPRATSIASVYPNADWYEREAFDLFGVHFDGRHDHRRILLPPLWEGHPLRKDQPARATEKPPFVMTAARFDAEEKALMIDPEALGLPTERDGVELMILNYGPHSMATHGVFRVVLALDGEEIVAARPDIGFHHRGAEKMGERQSWHQFIPYTDRIDYLGGVISEMPYLQAVERLCGITVPDRAKTIRIMLSEIYRIMNHLLLYGTMAQDCGAMSPVFYMFTDRERGYRIIEAITGARMHPGWFRIGGVAADLPEGWDRLVREFLDWMPKRLDDYAGMVLGNEIFRGRTVGIAAYDTATALDWGITGPGLRATGCDWDLRKARPYGGYENFEFEVPTGNNGDCYDRVLVRVEEMRQSLRIIRQCLDHMPSGPIKADHPLTTPPPRERMLHDIDTLIHHFVGVSWGPVVPAGEATGQAETVRGLTQYALVSDGATCSYRTRIRTPSFAHLQAVSAIAPGLTVADLVAYLGSIDYVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: UBIC_SALSV
Sequence: MSHPALTQLRALRYFDAIPALEPHLLDWLLLEDSMTKRFEQLGKRVSVTLIREAFVGQSEVEEASGLLPSESRYWLREILLCADGEPWLAGRTVVPESTLCGPEQVLQHLGKTPLGRYLFTSSTLTRDFIEIGRDATLWGRRSRLRLSGKPLLLTELFLPASPLY
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_MYCA1
Sequence: MAKKDGAIEVEGRVVEPLPNAMFRIELENGHKVLAHISGKMRQHYIRILPEDRVVVELSPYDLSRGRIVYRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSCL_NOVAD
Sequence: MAHEVKGEILGMLGEFKKFIARGNVLDLAVGVIIGGAFGKIVTSLTESVIMPVVGWLTGGVDFTRYFVRLGPVPADFKGDPTSYAELKAAGVPMIGYGDFITQAVNFVIVAFIIFLIVKAVNRMFEKPEEAPAAPSGPTEVELLAEIRDALKAKG
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROE_NOSS1
Sequence: MITGKTKLLGVIGHPVEHSLSPVMHNAAIAQLGLDYVYLPFPIAPDNLEAAIALLATIGVVGFSVTIPHKQAIIPLLSEISPVAQAIGAVNTVTRQNNQWVGTNTDIEGFIAPLQTTYKRDWSQQIAVILGNGGAARAVVAGCYQLGFAEIHVVGRNVQRLEEFRHSWENSPIAENLQVHTWDYLAKLIPQANLLVNTTPIGMYPQVDESPLSAEELVNLQTGTIAYDLIYIPKPTQFLQKAQQQGAIIIDGLEMLVQQGVAALKIWLQQDDIPVDVMRQALIKHLGLK
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: CB074_MOUSE
Sequence: MFTQSDTGKIEEIFTTNTMAFETTAITFFFILLICFICILLLLAIFLYKCYRGHNHEEPLKTLCTGEGCVAANAEMDKPEDQDKVLMHFLNMGLPMKPSILVQKQSKEEMATSLGDNIKAEDYQKKQTYEPVNARETNHEGELAEKMPIHVHRSSDTGSQKRPLKGVTFSKEVIVVDLGNEYPTPRSYAREHKERK
What are the official names of this protein?
Uncharacterized protein C2orf74 homolog.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NHAB_PHOLL
Sequence: METSILKTAVKNFLGNSPDWYKLAIIIFLIINPLIFFFINPFVTGWLLVIEFIFTLAMALKCYPLQPGGLLAIEAVIIGMTSPQQVGHEIANNLEVVLLLIFMVAGIYFMKQLLLFAFTKLLLSIKSKRMLALAFCLASAFLSAFLDALTVIAVVISVSLGFYSIYNNFITDQNDVINAKHDNHIDTAKKKQTLEQFRAFLRSLMMHAGVGTALGGVMTMVGEPQNLIIAKNVNWDFVTFFIRMAPITLPVFICGLLVCFLVEHFKLFGYGTELPERVRQVLEDYDKKTSAKRTHKEKAQLIAQALIGIWLIVALAFHLAEVGLIGLSVIILTTSFCGITEEHALGKAFEEALPFTALLTVFFSIVAVIVDQQLFTPFIQFVLQVSETSQLSLFYLFNGLLSSVSDNVFVGTVYINEARTAMQEGLISHKQFEYLAVAINTGTNLPSVATPNGQAAFLFLLTSTLSPLIRLSYGRMVIMALPYTIVMTLVGLLCVEFLLIPVTDMMVHWGLIALP
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FLIW_GEOKA
Sequence: MKIATKYHGDIEIHEKDIVRFEQGIPGFLEEKQFVLLPLEDTPFIILQSVNTPALGFVLIEPFSYFPTYEIELDDNTLEQLQITGEQDVALYVILTVADPFDDTTANLQAPIVINARKRLGKQVILTNTNYKTKHRLFPEKVAK
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1898_COXB2
Sequence: MPSFDIQSELNKHEVSNAVDQANREVATRFDFKGSGATYKYEGNSITLQAETDFQLKQMIDILQNKFAKRQIDVAHMKLEDPIIQHKSAQQTVMLLEGIDQTAAKKIIKLIKDQKLKVQAAIQGEKVRVTGKKRDDLQSVIGLLKEQEIGLPLQFDNFRD
What are the official names of this protein?
UPF0234 protein CbuG_1898.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: PYRC_SHEPW
Sequence: MTQLTIITPDDWHLHFRDGDMLQETVPATARLFNRAIVMPNLLPPVTDAKLASAYRERILAARPAGSTFEPLMTIFLTNNTTEQDIIDAKAAGVVAAKLYPAGATTNSDAAVKALDALFPIFEAMEKHGLLLLVHGEVTESHIDIFDREALFIERYLARIVNAFPGLKVVFEHITTKDAADFVMSAADNVAATITPQHLLLNRNDLLVGGVRPHNFCLPVLKRSTHQEALRAVVATGSSKFFLGTDSAPHEKHRKESACGCAGCYSAWSALELYAQVFDDLGALDKLEGFASIHGPDFYGLPRNTGSVTLVKETWTVPSEIILPNGNPIVPFFAGEEVSWKVKTA
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: QUEA_ACICJ
Sequence: MNLADFDYHLPPERIAAEPARPRHAARLLHVRGDGLDDRTILDLPALLAPGDLLVVNDTRVIPAQLTGRRGDARIGITLDRPLADGTWRVLLRNARRARPGETIAIDGAGGIAAEVIDRAPDGSATLRFDCDAETFRAMLDRAASLALPPYIPRPAGISEQDRQDYQTMFAAEEGAVAAPTAGLHFTETVLAALAARGVGLATVTLHVGAGTFLPVREDQLERHKLHAERGLIGPETAALVNATRARGGRIVAVGTTSLRVLETAAGDDGTLAPWHGETELFITPGYRFKLVDRLMTNFHLPKSTLLMLVAAFAGVERMRAAYAHAIARGYRFYSYGDASLLERA
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX141_LYCSI
Sequence: MMKVLVVVALLVTLISYSSSEGIDDLEADELLSLMANEQTRKECIPKHHECTSNKHGCCRGSFFKYRCQCTTVVTQDGEQTERCFCGTPPHHKAAELVVGFGKKIFG
What are the official names of this protein?
U1-lycotoxin-Ls1y, Toxin-like structure LSTX-A41.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 03 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YIDD_TREDE
Sequence: MRKLLVSFLCACIIFYQKAISPHFPPSCRYEPTCSQYAIESIKKYGPFKGAGMALLRILRCNPLCKGGYDPVP
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RSMA_STAA3
Sequence: MLDNKDIATPSRTRALLDKYGFNFKKSLGQNFLIDVNIINNIIDASDIDAQTGVIEIGPGMGSLTEQLARHAKRVLAFEIDQRLIPVLNDTLSPYDNVTVINEDILKANIKEAVENHLQDCEKIMVVANLPYYITTPILLNLMQQDIPIDGYVVMMQKEVGERLNAEVGSKAYGSLSIVVQYYTETSKVLTVPKSVFMPPPNVDSIVVKLMQRTEPLVTVDNEEAFFKLAKAAFAQRRKTINNNYQNYFKDGKQHKEVILQWLEQAGIDPRRRGETLSIQDFAKLYEEKKKFPQLEN
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NICA_ARATH
Sequence: MAMGLIRLLSIAFTLVLLSILPLHLSLADEITSIESVPDLQKLMYVAVDGFPCVRLLNLSGEIGCSNPGINKVVAPIIKLKDVKDLVQPHTILVTADEMEDFFTRVSTDLSFASKIGGVLVESGSNFQQKLKGFSPDKRFPQAQFSPYENVEYKWNSAASSIMWRNYNFPVYLLSESGISAVHEILSKKKMKHGTYTSDVAEFNMVMETTKAGTHNSEACLQEGTCLPLGGYSVWSSLPPISVSSSNNRKPVVLTVASMDTASFFRDKSFGADSPISGLVALLGAVDALSRVDGISNLKKQLVFLVLTGETWGYLGSRRFLHELDLHSDAVAGLSNTSIETVLEIGSVGKGLSGGINTFFAHKTRVSSVTNMTLDALKIAQDSLASKNIKILSADTANPGIPPSSLMAFMRKNPQTSAVVLEDFDTNFVNKFYHSHLDDLSNINSSSVVAAASVVARTLYILASDNKDTSNSALGSIHVNASFVEELLTCLLACEPGLSCNLVKDYISPTNTCPGNYAGVILGEPSSKPYLGYVGDVSRFLWNFLADKTSVQKGNTTSVCSKGVCSKTDEVCIKAESNKEGTCVVSTTRYVPAYSTRLKYNDGAWTILPQNSSDSMGMVDPVWTESNWDTLRVHVYTVQHSAYDNAVLVAGITVTTLAYIGILAAKSIITKALKQD
What is the function of this protein?
Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch.
What are the official names of this protein?
Nicastrin.
What is the protein family that this protein belongs to?
Belongs to the nicastrin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: APT_HAES1
Sequence: MNKLELIKSSIKSIPNHPKEGIIFRDITSLTEVPEAFQATIDLIIERYKSKGITKVIGTESRGFIFGAPVALALNVPFILVRKPGKLPRETIAQSYQLEYGQDTLEMHVSSIQAGDNVLVIDDLLATGGTIEATVKLVERLQGQVKHAAFVISLPDLGGEVRLRELGVEPFTLVEFSGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.