PharMolix/UniProtQA huggingface dataset:
Protein: PFD3_MOUSE
Sequence: MAAAKDGCGLETAAGNGRRLHLGIPEAVFVEDVDSFMKQPGNETADTVLKKLDEQYQKYKFMELNLAQKKRRLKGQIPEIKQTLEILKYMQKKKESTNSMETRFLLADNLYCKASVPPTDKVCLWLGANVMLEYDIDEAQALLEKNLSTATKNLDSLEEDLDFLRDQFTTTEVNMARVYNWDVKRRNKDDSTKNKA
What is the function of this protein?
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it.  Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity).
What are the official names of this protein?
Prefoldin subunit 3, von Hippel-Lindau-binding protein 1, VBP-1, VHL-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit alpha family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=In complex with VHL can translocate to the nucleus.
Protein: SODM_CHLTR
Sequence: MVFSSYMLPALPYDYDALEPVISAEIMQLHHQKHHQGYINNLNEALKSLDVANATQDLARLIAINPALRFNGGSHINHSLFWEMLAPQGKGGGVPPRHELLKLIEKFWGSFDNFLKNFITSSAAVQGSGWGWLAFCPQKQELMVQTTANQDPLEATTGMIPLLGVDVWEHAYYLQYKNARMDYLKSFPSIINWDYIENRFVEMSKQ
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: DCA13_MOUSE
Sequence: MKVKMLSRNPDNYVRETKLDIQRVPRNYDPTLHPFEVPREYVRALNATKLERVFAKPFLASLDGHRDGVNCLAKHPKSLASVLSGACDGEVKIWNLTKRKCIRTIQAHEGFVRGMCTRFCGTSFFTVGDDKTVKQWKMDGPGYGEEEEPLYTVLGKTVYTGIDHHWKDPVFATCGQQVDIWDEQRTSPVCSMNWGFDSISSVKFNPVETFLLGSCASDRNIVLYDMRQATPLKKVILEMRTNTICWNPMEAFNFTAANEDYNLYTFDMRALDTPVMVHMDHVSAVLDVDYSPTGKEFVSASFDKSIRIFPVDKSRSREVYHTKRMQHVMCVKWTSDSKYIMCGSDEMNIRLWKANASEKLGVLTSREKAANDYNQKLKEKFQYHPHVKRIARHRHLPKSIYSQIQEQRVMKEARRRKEMNRRKHSKPGSVPIVSERKKHVVAVVK
What is the function of this protein?
Substrate-recognition component of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex that plays a key role in embryo preimplantation and is required for normal meiotic cycle progression in oocytes (PubMed:30111536, PubMed:31492966).  Acts as a maternal factor that regulates oocyte and zygotic chromatin tightness during maternal to zygotic transition (PubMed:31000741).  Also involved in the transformation of the endometrium into the decidua, known as decidualization, providing a solid foundation for implantation of blastocysts (PubMed:35932979).  Recognizes the histone methyltransferases SUV39H1 and SUV39H2 and directs them to polyubiquitination and proteasomal degradation, which facilitates the H3K9me3 removal and early zygotic gene expression, essential steps for progressive genome reprogramming and the establishment of pluripotency during preimplantation embryonic development (PubMed:30111536).  Supports the spindle assembly and chromosome condensation during oocyte meiotic division by targeting the polyubiquitination and degradation of PTEN, a lipid phosphatase that inhibits PI3K pathway as well as oocyte growth and maturation (PubMed:31492966).  Targets PMP22 for polyubiquitination and proteasomal degradation (PubMed:35178836).
What are the official names of this protein?
DDB1- and CUL4-associated factor 13, WD repeat and SOF domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DCAF13/WDSOF1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=In the nucleolus, localizes predominantly in the granular component, but also detected in the fibrillar center and dense fibrillar component.
Protein: RS18_CHLSY
Sequence: MSRSRASGRPRSRRRECEFTKLGIVPDYKDVKRLQKYLTAQGKILPRRRTGVSAKMQRRLAVAIKRARHLALLPVAPSHTR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: CRCB2_STRAW
Sequence: MTVPHPESVGEPGIAVRAPARRRSAWHGQAPVVAVVALGGGIGGTARYAAALLWPTQSGGFPWTTFWVNVVGCAVIGVFMVVITDVWPAHRLVRPFFGTGVLGGFTTFSTYAVDIQKLVDAGHPRTALAYLAATLLAALAAVRLAATAARRVLVRRRR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CCSA_SYNE7
Sequence: MNLVSLQNSLDNATFAILLPTLLCYWTGVAFPNLKGLPAIGTAGMAIANLCMAALLGARWLEAGYFPISNLYESLFFLAWGLTAIHLLAEKLSGSRLVGAATSPLALGIVAFAAFTLPKEMRQAEPLVPALKSNWLMMHVSVMMVSYAALLVGSLLSVAFLVVTRGQAIELRGSSVGTGSFRQVKLNRASDLTIATAESGGSGGTAVLEQPVLQLAPEQLSLADTLDNVSYRVIGLGFPLLTIGIIAGAVWANEAWGSYWSWDPKETWALITWLVFAAYLHARITRGWQGRRPAILATVGFGVVWVCYLGVNLLGKGLHSYGWFF
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: C13A5_CAEEL
Sequence: MSLSILIAGASFIGLLTYYIWIWSFWIRKGVKGPRGFPFFGVIHEFQDYENPGLLKLGEWTKEYGPIYGITEGVEKTLIVSNPEFVHEVFVKQFDNFYGRKTNPIQGDPNKNKRAHLVSAQGHRWKRLRTLSSPTFSNKNLRKIMSTVEETVVELMRHLDDASAKGKAVDLLDYYQEFTLDIIGRIAMGQTESLMFRNPMLPKVKGIFKDGRKLPFLVSGIFPIAGTMFREFFMRFPSIQPAFDIMSTVEKALNKRLEQRAADEKAGIEPSGEPQDFIDLFLDARANVDFFEEESALGFAKTEIAKVDKQLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLARHPEIQKKLQEEVDRECPNPEVTFDQISKLKYMECVVKEALRMYPLASIVHNRKCMKETNVLGVQIEKGTNVQVDTWTLHYDPKVWGEDANEFRPERWESGDELFYAKGGYLPFGMGPRICIGMRLAMMEKKMLLTHILKKYTFETSTQTEIPLKLVGSATTAPRSVMLKLTPRHSN
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Putative cytochrome P450 CYP13A5.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: RS6_BORGP
Sequence: MIKRYEACFLFKSEEIEYKCSLEEVRKSLEFFGAIDIVSNFIGERALEYPIKKQARGRYEIIEFSMEGNNLKELESRLKLIKNLLRYMILVKIVRKINTKKIKRRNFREFRDNVDKESFKGGSKIETPTGSESTDIQEK
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: GATA_ASPFU
Sequence: MSLLREAEKCIANQRSHAALNAFITTVQHLGPLREQVRDAELRRESGRSKSEVDGRLIAFKDNICTRDFPTTCASGILAKFTSPFNATVVEQLSEAGAIVAGKTNLDEFGMGSHCLNSCFGPVKNQRQCQEGRILSAGGSSGGSAVSVATDQCYAALGTDTGGSVRLPAAYTGTVGFKPSYGLVSRWGVVAYANSLDTVGILAKNASTARDVFRIVNRHDPRDPTNLSPRSRSRIASHLQQPALLSRMTSSLRIGVPIEYNISELSPSVRRAWALSIAFLREQGHTIHPVSLPTTKLALSAYYVLAPAEASSNLAKYDGIRYGSRCNSPDSGGQPESYLYAKTRGDGFGLEVKRRILLGAFSLSADAINNYFIQAQRVRRLVQHDFNAVFRAEQPISPSRQKGDTELKSKQAEVDVLICPTAPSCPPQLADLVETDSIFSSLNAYTNDVFTVPASLAGLPAASVPVRVNCRDEGSSDADLAGIQIIGQYGDDELVLKVSESLEGKIF
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial, Glu-AdT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NUOI_BRUA1
Sequence: MASIAQAAKSLLLKEFASAFALSMRQFFAPKATLNYPHEKGPVSPRFRGEHALRRYPNGEERCIACKLCEAICPAQAITIEAGPRRNDGTRRTVRYDIDMVKCIYCGFCQEACPVDAIVEGPNFEFATETREELYYDKDKLLANGDRWEREIARNIAMDAPYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MURC_PSEE4
Sequence: MVESQKAMPQPKMGRIRRIHFVGIGGVGMCGIAEVLLNLGYEVSGSDLKASPVTERLESFGAEIFVGHRAENAASADVLVVSSAINPANPEVATALERRIPVVPRAEMLAELMRYRHGVAVAGTHGKTTTTSLLASVFAAGGLDPTFVIGGRLTAAGTNAQLGTSRYLIAEADESDASFLHLQPMVAVVTNIDADHMATYEGDFNKLKKTFVEFLHNLPFYGLAVMCLDDPVVREILPQVKRPTVTYGFSEEADIRAINVRQQGMQTHFTVLRRDCEPLEVSVNMPGNHNVLNALATIAIATDEGISDEAIVQGLSGFQGVGRRFQVYGELPVEGGSVMLVDDYGHHPTEVAAVIKAVRGGWPSRRLVIVYQPHRYSRTRDLYDDFVQVLGDANVLLLMEVYPAGEEPIPGADSRQLCHSIRQRGKLDPIYIERGAELAPLVKPLLRAGDILICQGAGDVGGLAPQLMKSPLFAGAKQEKSK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_BACC1
Sequence: MRILGLDVGTKTVGVAISDEMGWTAQGLETIKINEERGQFGFDRISELVKQYDVDKIVVGLPKNMNGTIGPRGEACQQFAENLRELLQLDVVMWDERLSTMAAERLLISADVSRKKRKQVIDKMAAVVILQGFLDSK
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_CLOBK
Sequence: MNFVIATRRSKLAQVQTEIIIDLLNKKHDIECEKLLIETVGDKILEVSLDKIGGKGLFVKDIEVAMLEQRADAAVHSMKDVPYEMPKGFEIIAIPEREDVRDAFISLDNIKFKDLRKGAKIGTSSRRRAAQLKLLRPDLDIVPIRGNVQTRIEKIKKENLDGIILAVAGLKRVNLDHLITDYFDTKEMVPAIGQGALGIEVMEEHPKKELFKDLDHYNSKICVLAERAFMRELDGDCHSTIGAYASIKDNIMHIIGIFERKNKIIKKEITGTKDQYEKLGIALAEHILKD
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: AROQ_XYLF2
Sequence: MAHLLLLHGPNLNLLGTREPEIYGRITLPQIDAALAERAATAGHGLSSLQSNAEHVLIERIHATREDGTAFILINPGAFTHTSVALRDALLAVALPFVEIHLSNPHTREPFRHHSYLADKALGVVCGFGVDSYRIALEGVIARLGSDV
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: MTPB_EUBLI
Sequence: MYVNRRFYDKYVSTRDVELLHEYSLRVLKEVGVSFDCEEALEIFKKHGATVEGSIVKIDEDLLNQALETAPKTFTITTSAGETKIGERYKPKTVGCYGPPKFLFEDDEYRVAKKDDMVKFLKLMDTSDVTDFVNNSAYDTPDLDKTKEDFYLPQVAMCLKYSQKPTYGNVANSMNVRGKSLKQEAKDIAKLYKEFYDIWDRPVLLTNTCALSPLGYSYEVLDNIMGLVEEGQPVTIITCSMTNLTAPAALLGSVIQNNATILAGIVLTQLINPGNPVIYGTVSTATDMRNVACSIGAPEAQLIQMASLALGRYYQLPVRTGIAGTDSLKPDYQAGVESFMILMTTYLGKSDFVLNHAGILQAYALGSYEKFVLDEEVNRILLRLNRGIDISDVKAEKVFDAIKKAGPLGNYLSGRTPKEYRQEHWLTKLFNRQAGNPQPIFDEIGDLRERASKEVEERVAGYTLPDLTKTQKDILNRYLPEDEKF
What is the function of this protein?
Involved in the degradation of the quaternary amine L-proline betaine (PubMed:31341018).  Component of a corrinoid-dependent methyltransferase system that transfers a methyl group from L-proline betaine to tetrahydrofolate (THF), forming methyl-THF, a key intermediate in the Wood-Ljungdahl acetogenesis pathway (PubMed:31341018).  MtpB catalyzes the methylation of the corrinoid protein MtqC, using L-proline betaine as the methyl donor (PubMed:31341018).  Shows weak activity with some other quaternary amines, including carnitine, phosphocholine, glycine betaine or betonicine, but cannot methylate free cob(I)alamin (PubMed:31341018).
What are the official names of this protein?
Proline betaine:corrinoid methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the trimethylamine methyltransferase family.
Protein: SRCA_ASPFU
Sequence: MNNEALAEDPPTPLWELVLEQFKDQLVLILLGSAAVSFVLALFEEGDDWTAFVDPVVILTILILNAVVGVTQESSAEKAIAALQEYSANEATVVRDGKTQRIKAEDLVPGDIIHIGVGDRVPADCRLLAIQSNSFRVDQAVLTGESESVSKDTRSIKDEQAVKQDQTNILFSGTSVVNGHATAIVVLTGASTAIGGIHESITSQISEPTPLKQKLNDFGDMLAKVITVICVLVWLINVEHFNDPAHGGWAKGAIYYLKIAVSLGVAAIPEGLAVVITTCLALGTRKMAAKNAVVRSLPSVETLGSCSVICSDKTGTLTTNQMSVEKLVYLNASGDDLEEIDVEGTTFAPEGKLSRNGKVLQNLAVTSSTVRQMAEVMALCNSATLAHDPKSGTFSCIGEPTEGALRVLVEKIGTDDMATNEKLFRLPASQRLHVSSAHYESRLPLLATYEFSRDRKSMSVLVTKDKAQRLLVKGAPESILERCSYVLLGPDGPRVPLTRVYSDLLAREVVEYGNRGLRVIALASVDDIADNPLLHNAQTTEEYAQLERNMTLIGLVGMLDPPRTEVADSVKKCRAAGIRVIVITGDNRNTAESICRQIGVFGEDEDLTGKSFTGREFDALSESEKLEAVKKASLFSRTEPSHKSKLVDLLQSLGHVVAMTGDGVNDAPALKKADIGVAMGTGTDVAKLAADMVLTDDNFATITVAVEEGRSIYSNTQQFIRYLISSNIGEVVSIFLTAALGMPEALIPVQLLWVNLVTDGLPATALSFNPPDHDVMRRAPRKRDEPLVGGWLLFRYLAIGTYVGAATVFGYIWWFVYNPEGPQISFWQLSHFHKCSAQFPEIGCEMFSNEMSRSASTVSLSILVVIEMLNAMNALSSSESLLAFPLWNNMMLVYAIILSMTLHFAILYIPFLQTLFSILPLNWTEWKAVLAISAPVVAIDELLKYAERRLYTLPAIAGEQQNGVAFKPKKA
What is the function of this protein?
Magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the endoplasmic reticulum lumen (Probable).  Its activity is coupled to the unfolded protein response (UPR) and Ca(2+) import into the endoplasmioc reticulum is important for redox homeostasis, virulence, cell wall biosynthesis, and resistance to antifungal compounds that inhibit Ca2+ signaling (PubMed:32487759, PubMed:34663092).  With pmrA, promotes radial growth and conidiation (PubMed:32487759).
What are the official names of this protein?
Endoplasmic reticulum calcium ATPase srcA, Calcium pump srcA, Endoplasmic reticulum class 1/2 Ca(2+) ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
Protein: Z11_DORVU
Sequence: MKKTFLPIFLVILLASYALANPQVTFSRDWGPGKK
What is the function of this protein?
Potently activates insect G protein-coupled receptor.  It activates the ACP receptor (ACPR) from the mosquito A. aegypti (EC(50)=0. 55 nM) with a potency comparable to that of the endogenous ligand.  Has no activity on receptors of the closely related neuropeptides adipokinetic hormone and corazonin.  In vivo, does not reveal any observable effects when injected into crickets (A. domesticus).  Does not induce increase in intracellular calcium in mouse DRG neurons, suggesting that it does not induce pain.
What are the official names of this protein?
Z-limacoditoxin(1)-Dv1, Z-LCTX(1)-Dv1, Vulnericin.
What is the protein family that this protein belongs to?
Belongs to the limacoditoxin-1 (ACP-like) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPG_WOLSU
Sequence: MQERVKTKKIFVGDVAIGGDAPISVQSMTFSKTADIGATKAQIDRLALAGCDIVRVAVSDHEDANALKELKRLSPLPLVADIHFRYKLALIAAQSVDCIRINPGNIGSKEKIKAVADACAERGIPIRIGVNGGSLEEMFEQKYGATPRGMVESALYNIKLLEDFGFANIKVSLKASDVERTVLAYRELRPLVEYPFHLGVTEAGTLFHSMIKSSMALGGLLLEGIGDTMRVSITGELEQEVEVARAILKYSGRQKEGVYLISCPTCGRIEADLVSAVKRVEERVKHIRAPLQISVMGCAVNALGEAKHADIAIAFGRGDGLIIKKGEILCKLPEEELVDRLVEEAEKLEREYLEDSFKN
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: FMT_XYLFT
Sequence: MRIVFAGTPDFAVPSLRSVTQRADVVAVYTQPDRPAGRGRELMPSPVKLEAVARGLPVYQPQTLRSPEVLEQLRALRPDLIVVVAYGVILPEAVLTIPDDGCWNVHASLLPRWRGAAPIQRAIEAGDTETGVCLMQMEAGLDTGPVLMSLKTPINAHETSGQLHDRLAEMGAQLLSDGLGLLRAGLRPVPQPQLAVGVTYAHKLGKVESRLDWEQPAERLACRVRAFQPWPVAEVVLSGERVRIHEALALDLDHSQPPGTVLAASKEGIDVACVQGALRLCRLQREGGKAITVADYLNARRDLQVRA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RL18_THIDA
Sequence: MNTKQSRIRRARKTRAKIAAVKAIRLAIHRTNSHIYAQIISADGGTVMASASSNDKDLRGQLANGGTTAAAAAVGKRLAEKAKGLGIEKVAFDRAGFKFHGRVKALAEAAREGGLAF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: UCP1_PHOSU
Sequence: MVSQTTSEVQPTMGVKIFSAGVAACLADIITFPLDTAKVRLQIQGEGQTSSTIRYKGVLGTITTLAKTEGLPKLYSGLPAGIQRQISFASLRIGLYDTVQEYFSSGKETPPTLVNRISAGLMTGGVAVFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTESLSTLWKGTTPNLLRNVIINCTELVTYDLMKGALVNNQILADDVPCHLLSALVAGFCTTFLASPADVVKTRFINSLPGQYPSVPSCAMTMFTKEGPTAFFKGFVPSFLRLASWNVIMFVCFEQLKKELMKSRQTVDCTT
What is the function of this protein?
Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates in non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance.  Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane.  However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in an apparent transport of protons activated by LCFAs.  Thereby, dissipates the mitochondrial proton gradient and converts the energy of substrate oxydation into heat instead of ATP.  Regulates the production of reactive oxygen species/ROS by mitochondria.
What are the official names of this protein?
Mitochondrial brown fat uncoupling protein 1, UCP 1, Solute carrier family 25 member 7, Thermogenin.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y562_THEKO
Sequence: MPRGMGWGRGRGRRRKMRMIGFIPQVRHFYPAQPPVFQPKPPIFMTYEEFEALRLVDYEGLTQEEAGQRMGVSRGTVWRALTSARKKVAQMLVEGRELIILPGGNEVPRGADE
What are the official names of this protein?
UPF0251 protein TK0562.
What is the protein family that this protein belongs to?
Belongs to the UPF0251 family.
Protein: Y2070_EXIS2
Sequence: MQQNEPTHYVIPDGEGNEFKFAERLRYESPRSSKTYIFLEPVGADYDEAEEVDIFVYELEEYGEGDDDFNLVPIAEDDAETWDEIEEVFNTLEDELD
What are the official names of this protein?
UPF0473 protein Exig_2070.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: LEXA_YERPN
Sequence: MKALTTRQQEVYDLVRDHLAQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVIEIVSGASRGIRLLMEEEEGLPLIGRVAAGEPLLAQQHIEGHYKVDPSLFKPGADFLLRVNGMSMRDIGILDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKKQGNIVHLLPENSEFQPIVVDLREQSFTIEGLAVGVIRNGDWI
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RL2_ECOL6
Sequence: MAVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLLEKNSKSGGRNNNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGDQIQSGVDAAIKPGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: KCS18_ARATH
Sequence: MTSVNVKLLYRYVLTNFFNLCLFPLTAFLAGKASRLTINDLHNFLSYLQHNLITVTLLFAFTVFGLVLYIVTRPNPVYLVDYSCYLPPPHLKVSVSKVMDIFYQIRKADTSSRNVACDDPSSLDFLRKIQERSGLGDETYSPEGLIHVPPRKTFAASREETEKVIIGALENLFENTKVNPREIGILVVNSSMFNPTPSLSAMVVNTFKLRSNIKSFNLGGMGCSAGVIAIDLAKDLLHVHKNTYALVVSTENITQGIYAGENRSMMVSNCLFRVGGAAILLSNKSGDRRRSKYKLVHTVRTHTGADDKSFRCVQQEDDESGKIGVCLSKDITNVAGTTLTKNIATLGPLILPLSEKFLFFATFVAKKLLKDKIKHYYVPDFKLAVDHFCIHAGGRAVIDELEKNLGLSPIDVEASRSTLHRFGNTSSSSIWYELAYIEAKGRMKKGNKAWQIALGSGFKCNSAVWVALRNVKASANSPWQHCIDRYPVKIDSDLSKSKTHVQNGRS
What is the function of this protein?
Contributes to fatty acids elongation and stockage in developing seeds.  Active on both saturated and mono-unsaturated acyl-CoAs of 16 and 18 carbons.  Required for the elongation of C18 to C20 and of C20 to C22 fatty acids.  Mediates also the synthesis of VLCFAs from 20 to 26 carbons in length (e. g.  C20:1, C20, C22:1, C22, C24:1, C24, C26) (PubMed:15277688, PubMed:16765910, PubMed:7734965, PubMed:9263455, Ref. 4, Ref. 5, PubMed:12135493, PubMed:23145136).  Has no activity with polyunsaturated C18:2 and C18:3 or with acyl-CoAs having 22 carbons or longer chain length (PubMed:12135493).
What are the official names of this protein?
3-ketoacyl-CoA synthase 18, KCS-18, Protein FATTY ACID ELONGATION 1, Very long-chain fatty acid condensing enzyme 18, VLCFA condensing enzyme 18.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
What are the subcellular locations of this protein?
Microsome membrane; Multi-pass membrane protein.
Protein: SPEB_CHICK
Sequence: MICLLRTARLSARLLFASAAAPCRRASRFNVPPSAEFVARPVGVCSMLRLPVQTSAEGLDAAFVGVPLDTGTSNRPGARFGPQQIRAESVMVRRYNASTGAAPFDSLLVADVGDVNVNLYNLPDSCRRIRESYQKIVASGCVPLTLGGDHSITYPILQAVAEKHGPVGLVHVDAHTDTSDMALGEKIYHGTPFRRCVDEGLLDCSRVVQIGIRGSSYAPNPYKYCWDQGFRVVPAEECWMKSLVPLMGEVRQQMGDGPVYISFDIDGLDPAYAPGTGTPEIAGLTPMQALEIIRGCKGLNIVGCDLVEVAPIYDVSGNTALLGANLLFEMLCVLPGVKTM
What are the official names of this protein?
Agmatinase, mitochondrial, Agmatine ureohydrolase, AUH.
What is the protein family that this protein belongs to?
Belongs to the arginase family. Agmatinase subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS21_ACIBY
Sequence: MPQVKLKEGEPVDVAIRRFKRSCEKAGVLADVRKREFYEKPTQERKRKKAAAVKRYQKKLARESVRTTRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.