PharMolix/UniProtQA huggingface dataset:
Protein: POPD1_CHICK
Sequence: MDTTAISPLTPLGVIPDLKNATSVPFNETACENWKEIHHLVFHVANICFAAGLVIPTTLNLHMIFLRGLLTVGCALFIIWATLYRCALDIMIWNSVFLVVNLLHFIYLVYKRRPIKIEKELSSLYKRMFEPLHVPPELFQRLTGQFCNIQTLKTGQAYAAEDKTSVDDRLSILLKGKMKVSYRGHFLHNIYPCAFIDSPEFRSTQMNRGEKFQVTIIADDNCKFLCWSRERLTYFLETEPFLYEIFKYLIGKDITNKLYSLNDPTLNDKASKKIDRQPSLCSQLSVMQMRNSMASTSDSEDGLQMFLRGTSSSSSLRPGRTSPYLRTSAKMKPIEESVEDDVFEAPSAEKLELQRLP
What is the function of this protein?
Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity.  Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells.  Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner.  Involved in epithelial movement during corneal sheet formation and regeneration.  May play a role in VAMP3-mediated vesicular transport and recycling of receptor molecules.  May play a role in the regulation of cell shape and movement by modulating the Rho-GTPase activity.  May be involved in skeletal muscle and heart development as well as in the maintenance of heart function (By similarity).  May also be involved in striated muscle regeneration and in the regulation of cell spreading.
What are the official names of this protein?
Blood vessel epicardial substance, Popeye domain-containing protein 1, Popeye protein 1.
What is the protein family that this protein belongs to?
Belongs to the popeye family.
What are the subcellular locations of this protein?
Lateral cell membrane. Cell junction, tight junction. Membrane; Multi-pass membrane protein. Cell membrane, sarcolemma. Membrane, caveola. Note=Detected at points of cell-cell contact in confluent epithelial sheets. Colocalizes with components of the adherens and tight junctions.
Protein: DNLJ_META1
Sequence: MTEKEKIRNEVFELQAKINEWDNAYYNLDAPLVEDAIYDREILKLKKLEEQYSSYFSFEELANSPTQKINAKSSDLFKKVTHDSPMLSLNKAYTEEEIQKFIDNIKKVTPTFSFFLEPKIDGLSISIKYRNGQLFQAVTRGDGLVGEDVTENIKQIKNIPKEIAYQKPLEVRGEVYLALSEFEKINLNFQKENKPLMANPRNAAAGTLRQLDKEIVANRNLSAFLYNIVAPEDHNIFTILEARDFLKNLGFSVTKEATYAKDLSEINSYIENFKHLKKTLDYETDGVVIKLNELQHYDALGATNKFPHSAIAFKYEPNTTTTVLKNIFITVGRTGLVTYNAELEPVILSGSCITFATLNNYQYIKDLKLNKGDLVYIKKAGEIIPCVIGLVNKKHEETEFNKFLKCPYCNSDLIETDTLLEQYCSNENCPEIRRKKIIHFASKKAMELNSLGEKNIDVFINEGLLENVIDFYKLKEKKDKIMSLERFGTKSVMNILKSIEESKKNSLDRVIFGLSIKHIGSKVAYFLASKILKLSNFLDFDFDSLISYNEIGEKIISSLKNWVAKEENKNLVKDLLDNDVDLEFIATKKTERFAQLSFVITGTLSQPRSHFEKLIKENGGSISSAVSAKTSYLLVGEDAGSKLAKARALNVKILDEEAFNELLVS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: FZD5_MOUSE
Sequence: MARPDPSAPPSLLLLLLAQLVGRAAAASKAPVCQEITVPMCRGIGYNLTHMPNQFNHDTQDEAGLEVHQFWPLVEIHCSPDLRFFLCSMYTPICLPDYHKPLPPCRSVCERAKAGCSPLMRQYGFAWPERMSCDRLPVLGGDAEVLCMDYNRSEATTASPKSFPAKPTLPGPPGAPSSGGECPSGGPSVCTCREPFVPILKESHPLYNKVRTGQVPNCAVPCYQPSFSPDERTFATFWIGLWSVLCFISTSTTVATFLIDMERFRYPERPIIFLSACYLCVSLGFLVRLVVGHASVACSREHSHIHYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYAQYFHLAAWLIPSVKSITALALSSVDGDPVAGICYVGNQNLNSLRGFVLGPLVLYLLVGTLFLLAGFVSLFRIRSVIKQGGTKTDKLEKLMIRIGIFTLLYTVPASIVVACYLYEQHYRESWEAALTCACPGPDAGQPRAKPEYWVLMLKYFMCLVVGITSGVWIWSGKTLESWRRFTSRCCCSSRRGHKSGGAMAAGDYAEASAALTGRTGPPGPTAAYHKQVSLSHV
What is the function of this protein?
Receptor for Wnt proteins (PubMed:11092808, PubMed:18230341).  Can activate WNT2, WNT10B, WNT5A, but not WNT2B or WNT4 (in vitro); the in vivo situation may be different since not all of these are known to be coexpressed (PubMed:11092808).  In neurons, activation of WNT7A promotes formation of synapses (By similarity).  Functions in the canonical Wnt/beta-catenin signaling pathway (PubMed:18230341).  The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes (PubMed:18230341).  A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase.  Both pathways seem to involve interactions with G-proteins.  May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (Probable).  Plays a role in yolk sac angiogenesis and in placental vascularization (PubMed:11092808).
What are the official names of this protein?
Frizzled-5, Fz-5, mFz5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Synapse. Perikaryon. Cell projection, dendrite. Cell projection, axon. Note=Localized at the plasma membrane and also found at the Golgi.
Protein: NS49_CVBOK
Sequence: MTTKFVFDLLAPDDILHPSNHVNLIIRLIEVEHIIIATTMPAV
What are the official names of this protein?
Non-structural protein of 4.9 kDa, ns4.9, 4.9 kDa accessory protein.
What is the protein family that this protein belongs to?
Belongs to the coronaviruses ns4.9 protein family.
Protein: TRPG_ASPAW
Sequence: MADSGLVDHSPHHPTKAAQLNTASNVILIDNYDSFTWNVYLVLEGATVNVFRNDQITLEELIAKKPTQLVISPGPGHPETDAGISSAAIQYFSGKIPIFGVCMGQQCIITCFGGKVDVTGEILHGKTSALKHDGKGAYEGLPDSLALTRYHSLAGTHATIPDCLEVSSSVQLTDDSNKDVIMGVRHKKLAVEGVQFHPESILTEYGRTMFRNFLKLTAGTWEGNGKHFDEQSNTTKATVSSNTAPKTDKKLSILERIYDHRRAAVAVQKTIPSQRPADLQAAYDLNLAPPQVPFPARLRQSPYPLSLMAEIKRASPSKGMIAENACAPAQARQYAKAGASVISVLTEPEWFKGSIDDLRAVRQSLEGLTNRPAILRKEFVFDEYQILEARLAGADTVLLIVKMLSVELLTRLYHYSRSLGMEPLVEVNTPEEMKIAVDLGAEVIGVNNRDLTSFEVDLGTTSRLMDQVPSSTIVCALSGISGPKDVEAYKKEGVKAILVGEALMRAADTAAFIAELLGGSSQNVSKESRSSPLVKICGTRSEEAARAAIEAGADLIGIIMVQGRTRCVPDDVALRISQVVKSIPKPAGQTPPTSRGTPAAASVEYFDHSARILRHPSRALLVGVFQNQPLDYILSQQQKLGLDVVQLHGSEPLEWAKLIPVPVIRKFGLDEPAIARRAYHSLPLLDSGVGGTGELLDQSRVQNVLDKDSGLRVILAGGLDPTNVAGIVQKLGESGRKVVGVDVSSGVESDGAQDLGKIRAFVQAVRGL
What is the function of this protein?
Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.
What are the official names of this protein?
Multifunctional tryptophan biosynthesis protein.
Protein: CINAL_LEPBP
Sequence: MTPYIVILSTGSELTAGRSVDTNSGWIANQLFELGWKVKKIITLPDDPNLIFKELEALQSLAKEIPVLAIMTGGLGPTEDDYTLETVLKLTGKTSYAVEKAKIRLTKIYEARGKDYKDILPTVFRQTNVPEGCKTLDNSVGIAVGFIESLGENSYLVCMPGVPSEMTEMFKRRLVPELKKMYPRENLIQKTKWLWNIGESLFQNEFIEPNREVYFKETEWGVTANRGYIKCIFQSTNDVMLDTILKSLEKQYPDLISDDVFQYVHEQLLYEKWTISVVESCTGGLLGKKLTERAGSSAYFMGGFLTYSNEMKSNLLGIPKETIETFGAVSDEVAFAMVDGLCLKTGTDFGVSITGIAGPEGGSEEKPVGTVCIGLKEPNGKIKVHRYLFPGNRESIRENASNTALFLIYQSLKGKVV
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: URED_CUPPJ
Sequence: MRHPDFPSAVAVPPAWQASLRLRFAARGERTVLAARQHRGPLMVQKPLYPEGDICHAVILHPPAGVAGGDTLDIALHAEAGTHAVIATPGATKWYKSLGRDASQHVRLTVEEGARLDWLPQENIVFDDARARIATELSIAPGGSAIGWDAVVLGRQASGEQWNRGVLWLDTQVRCNGHALWIEQSQLDAGSPLRGAVAGLDGMSVLGTLWAVGHGATQELAESLAERLPYAAGLRAGVTCLSSPAQSMLLVRVLGRQMEAVRHVMVDAWSALREPIHGVPARPLRLWAT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIS1_DROVI
Sequence: MKMVLSQRQREELNQAIADYLGSNGYADSLEAFRKEADLSTEAEKKFGGLLEKKWTSVIRLQKKVMELEAKLTEAEKEVIEGAPTKNKRTPGEWIPRPPEKYSLTGHRASITRVIFHPIFGLMVSASEDATIKIWDFETGEYERSLKGHTDSVQDVAFDAQGKLLASCSADLSIKLWDFQQSYECVKTMHGHDHNVSSVAFVPAGDYVLSASRDRTIKMWEVATGYCVKTYTGHREWVRMVRVHIEGSIFATCSNDHTIRVWLTNSKDCKVELRDHEHTVECIAWAPEAAASAINEAAGADNKKGHHQGPFLASGSRDKTIRIWDVSVGQCLLTLNGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWECR
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Required for several dynein- and microtubule-dependent processes.
What are the official names of this protein?
Lissencephaly-1 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes to the plus end of microtubules and to the centrosome.
Protein: YIDD_RICM5
Sequence: MTRILLLLLRFYQYFISPLLSNNCRFHPTCSEYAKEAISMHGSIKGLWLTFKRIIKCQPFCDGGYDTVPISIKNSKPLNKKI
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PG068_VAR67
Sequence: MDFIRRKYLIYTVENNIDFLKDDTLSKVNNFTLNHVLALKYLVSNFPQHVITKDVLANTNFFVFIHMVRCCKVYEAVLRHAFDAPTLYVKALTKNYLSFSNAIQSYKETVHKLTQDEKFLEVAEYMEELGELIGVNYDLVLNPLFHGGEPIKDMEIIFLKLFKKTDFKVVKKLSVIRLLIWAYLSKKDTGIEFADNDRQDIYTLFQHTGRIVHSNLTETFRDYIFPGDKTSYWVWLNESIANDADIVLNRPAITMYDKILSYIYSEIKQGRVNKNMLKLVYIFEPEKDIRELLLEIIYDIPGDILSIIDAKNDDWKKYFISFYKANFINGNTFISDRTFNEDLFRVVVQIDPEYFDNERIMSLFSTSAVEIKRFDELDINNSYISNIIYEVNDITLDTMDDMKKCQIFNEDTSYYVKEYNTYLFLNETDPMVIENGILKKLSSIKSKSRRLNLFSKNILKYYLDGQLARLGLVLDDYKGDLLVKMINHLKFVEDVSAFVRFSTDKNPSVLPSLINTILASYNISIIVLFQKFLRDNLYHVEKFLDKSIHLTKTDKKYILQLIRHGRS
What is the function of this protein?
Plays an essential role for maintaining proper localization of the seven-protein complex and the viroplasm during assembly.
What are the official names of this protein?
Protein OPG068, Protein E6.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG068 family.
Protein: PANB_SULIA
Sequence: MKKVTIRDFIKKKSTKEKITILTAYDYPTAKIISNTGLDSILVGDSLGMVVLGYANTLNVTMRDMISHTRAVARANPPQLIVADMPFLSYEIDTKSAVKNAGLLVKAGSDAIKLEGGEEMKDTVKAIVKAGIPVMGHIGLTPQRFLRLGGFRTIGKTKQEEDQLIKDSLELEDAGVFSLVIENTYVDIAKRITEKLNIPTICIGAGPYCDGQVLVINDLLGLSEFTPYFAKSYVNLKEIISNAINQYIIDVKNNKFPEKQHYKEKES
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_GRABC
Sequence: MNRRTRPRTASRVAAVQALFQGEQAQESLEAVIEQFVRFRLGALPGQDGFEDGRIPDAEVPLFSRIVRAATKEQDVIDPLLITALPAEWPLARLDPVLRALLRAGACELRMKDGPPPRVVINEYLDIAHGFFQGEEPRMVNGILNALARQLRPEEFAGERQQG
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: SYW_LEIXX
Sequence: MTDSPRLYSGMQPSADSLHLGNYVGALLQWKELQAAHDAFFSVVDLHAITVAQDPHDLREKTRRTAAQYIAAGIDPSVSTLYVQSHVPAHAQLAWVLSTITGYGEAARMTQFKDKSAKQGAEATSVGLFTYPVLMAADILLFDADVVPVGDDQRQHVELTRDLAERFNSRFGETFVVPQAMILKDGARIYDLQSPESKMSKSADSGAGIVWLLDEPDIARKKIMRAVTDTDGVVSYDRAGKPGVSNLLSIYSALSGRAIQQIELDYEGKGYGDFKKGLVEVVVDALGPIRERTLELLADPAELDRILAGNAARAGEAAEITLAKAYEAIGFLQPTRR
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDUB5_MACFA
Sequence: MAGMSLLRRVSVTAVAALSGRSLGTRLGFGGFLTRGFPKAVAPVRHSGGHGKRLFVIKPSRFYDIRFLKLLRFYIALTGIPVVIIITLVNVFIGEAELAEIPEGYIPEHWEYYKHPISRWIARNFYDSPEKIYEKSMAVLQIEAEKAELRLKELEVRRLMRMRGDGPWYYYETIDKELIDHSPKATPDN
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial, Complex I-SGDH, CI-SGDH, NADH-ubiquinone oxidoreductase SGDH subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB5 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Protein: FNTA_MOUSE
Sequence: MAATEGVGESAAGGEPGQPEQPPPPPPPPPAQQPQEEEMAAEAGEAAASPMDDGFLSLDSPTYVLYRDRAEWADIDPVPQNDGPNPVVQIIYSEKFRDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLRSLQKDLQEEMNYITAIIEEQPKNYQVWHHRRVLVEWLKDPSQELEFIADILSQDAKNYHAWQHRQWVIQEFRLWDNELQYVDQLLKEDVRNNSVWNQRHFVISNTTGYSDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSRYPNLLNQLLDLQPSHSSPYLIAFLVDVYEDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYIGRSLQSKHCRESDIPASV
What is the function of this protein?
Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex.  Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.  May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation.
What are the official names of this protein?
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, CAAX farnesyltransferase subunit alpha, FTase-alpha, Ras proteins prenyltransferase subunit alpha, Type I protein geranyl-geranyltransferase subunit alpha, GGTase-I-alpha.
What is the protein family that this protein belongs to?
Belongs to the protein prenyltransferase subunit alpha family.
Protein: ATPA_WOLPM
Sequence: MKNSMNVSEIASIIREKVETFDNPIKRENIGEVISVTDGIALVYGLEKAKFGEKVFFASGVEGIVLDLDHNTAGIVVLGNDRDVKEGDVVKCSGDVVQVPVGHELLGRVVNALGHPMDDGGEIRAKNRMDIESKAPGIIDRKSVHEPLQTGIKIIDLLIPIGRGQRELIIGDRQIGKTTIALDTIINQKKVNDEVNENQKVYCVYVAIGQKISTVAKVVNKLKESGALEYTTVVVASASDCAPMQFLAPYAGCTIGEFFRDNGMHCLIIYDDLSKHAVAYRQMSLLLRRPPGREAYPGDIFYVHSRLLERAAKMSDKKGQGSLTALPIVETQAGDVSAYVPTNVISITDGQIFLESELFYKGFRPAVNIGLSVSRVGSAAQLKSVKKVAGSIKLSLAQYRELEDFAKFGSDLDASVQLSLNKGKYLVELLKQKQHLPMSIEEQVVLMYIFSNLYNQLSKIQISNVNKFEHDLVNYFRTVHPGVLKKLSNDMNGDIKGDIFNIVSNFVTQFNCV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: IRC22_CANGA
Sequence: MKFLHIGLMTLMAGVSNVLAQEEANAEDVMVNIEGQDMTMEEAEAYMAAKEKMGGAQQQREMINLQVNYDLLEEPFADLQDFIVFEVGETATLNYTIHNLDQEETYSIVGVSGAVLSEVDQRNVANLTETNITEIVLAPNATGTLRHKIDMNLTEGRYYILPLLHVKDKNEVKRVMSNTFKLDLINQSISIFDPSFLSIIAVLIALVGGTVYLYSNVVAPPKKIKKKEAIPAKIDESWLPDVHKK
What is the function of this protein?
Is probably involved in a pathway contributing to genomic integrity.
What are the official names of this protein?
Increased recombination centers protein 22.
What is the protein family that this protein belongs to?
Belongs to the IRC22 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: CH602_STRLI
Sequence: MAKIIAFDEKARRGLEGGMNQLADAVKVTLGPKGRNVVLEKKWGAPTITNDGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVKEGLRNVAAGANPMALKRGIEKAVEAVSGALLEQAKDVETKEQIASTASISAADTQIGELIAEAMDKVGKEGVITVEEFQTFGLELELTEGMGFDKGYISAYFATDMERMEASLDDPYILIANSKIGNVKDLLPLLEKVMQSGKPLLIIAEDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLGDIAILTGGEVISEEVGLKLENAGLDLLGRARKVVITKDETTIVDGAGDTDQVNGRVAQIRAEIENSDSDYDREKLQERLANVAGGVAVIKAGAATEVELKERKERKHRIEDAVRNAKAAVEEGIVAGGGVALLQASQVFEKLELTGDEATGANAVKLALEAPLKQIPSTAVSRAAWSWRRCATSPWATA
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK23_DRIGR
Sequence: MDGIKYAVFTEKSIRLLGNNQYTSNVESGSTRTEIKHWVELFFGVKVIAMNSHRLPGKGRRMGPIMGHTMHYRRMIITLQPGYSIPPLIEKRT
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TPIS_ALKOO
Sequence: MRKPIIAGNWKMNKVSKEALDLVNQIKDEVHKTEVEVVVCCPFTVLSQVQKALVGTNLKLGAQNMHWEEDGAYTGEISANMLKDIGVEYVILGHSERRQYFNETDETVNKKVKKAIKENLKPIVCIGESLEEREANQTFDVIKKQLLGAFEGVPAEAMDNVVLAYEPIWAIGTGKTASSEEAQTVIAYIRSLIEEKYGVDISEEVRIQYGGSVKASNATEIMNETDIDGALVGGASLKAEEFLGIINF
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_HELPH
Sequence: MMKIVIDLMGADHGVLPIIEGVSRALENKSFSAVLVGDKDKATPFISKELASKVEMIHTQDYIKMEEAATEAIKRKESSIYLGMDILKNGADALISAGHSGATMGLATLRLGRIKGVERPAICTLMPSVGKRPSVLLDAGANTDCKPEYLIDFALMGYEYAKSVLHYDSPKVGLLSNGEEDIKGNMLVKETHKMLKAYDFFYGNVEGSDIFKGVVDVVVCDGFMGNVVLKTTEGVASAIGSIFKDEIKSSFKSKMGALMLRNAFDILKQKTDYAEYGGAPLLGVNKSVIISHGKSNARAVECAIYQAISAVESQVCLRITQAFESLKPSVSAHQSDQQDA
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: VM2SA_GLOSA
Sequence: MIQVLLVTICLVIFPYQGSSIILESGNVNDYEVVYPQKVTALPKGAVQPKYEDAMQYEFKVNGEPVVLHLEKNKGLFSEDYSETHYSPDGRKITTNPPVEDHCYYHGRIQNDADSTASISACNGLKGHFKHQGEMYLIEPLKLSDSEAHAVYKYENVEKEDEAPKMCGVTQTNWKSDEPIKKASQLVVTPEQQRFPQRYIELVVVADQGMFTKYNSNLDTIRTWVHELVDTINEFYRSLNVRVSLTELEIWSNEDLINVQPAAPHTLDSFGEWRQRDLLHRISHDNAMLLTSTDFDGDTIGFAHVGTMCDPKRSVGIVQDHSAINLLVAVTMAHELGHNLGTDHDGNQCHCSANSCIMGDVLREGLSYEFSDCSQNQYQTYLTDHNPQCILNEPLRTDTVSTPVSGNELLETGEECDCGTPANPCCDAATCKLRPGAQCAEGLCCDQCKFTRAGKICRRARGDNPDDRCTGQSSDCPRNPFHA
What is the function of this protein?
Binds and inhibits integrins.
What are the official names of this protein?
Zinc metalloproteinase/disintegrin.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IId sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YIAL_ECOLI
Sequence: MIFGHIAQPNPCRLPAAIEKALDFLRATDFNALEPGVVEIDGKNIYTQIIDLTTREAVVNRPEVHRRYIDIQFLAWGEEKIGIAIDTGNNKVSESLLEQRNIIFYHDSEHESFIEMIPGSYAIFFPQDVHRPGCIMQTASEIRKIVVKVALTALN
What are the official names of this protein?
Protein YiaL.
What is the protein family that this protein belongs to?
Belongs to the TabA/YiaL family.
Protein: KTRC_AREMA
Sequence: LGYLGTCPTNIGTGLR
What are the official names of this protein?
Taurocyamine kinase.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: RL33_METNO
Sequence: MAKAVTVKIKLVSTADTGYFYVTKKNSRTQTEKLSFKKYDPVARKHVEFKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: PACC_CRYNJ
Sequence: MAYPTLPPNLLSTPNTYSDSVSPTDPEPITPELVSREPEKPAQKAAKTAMNNTSTASKPSESKGETLPCKWTGCSHISDSPDELYDHLCTVHVGRKSTNNLCLTCGWENCGTKCVKRDHITSHLRVHTPLKPHPCAVCGKTFKRPQDLKKHERIHTAEHHQLHKLSKAPTTADPEFNSRVSLSSATRIDRPRSPLSTSLSPTSTSSHSLHSSSSPFDHLLATGFHTDKSVSPTPSALALLHKKQHEELAAYQQKEMLVLQQLAFNQQQSQAYAARLAAEPFGTGAGAKRGQADAFHDLLSDVKKRKVEPVYDQDMIHRLNALVPPSLPTSFPTLPSLGGYNQYQTFPSFNGYPSLPSLHTSIYPTTAPQAQYSNQSPLPIPEIKTEADLAMFNEFMISLGRDAAANKAGPHPMTQSASGSGASNGYSASNSGTPLSETSGGVEDLFNAEELASLGLAGMPGISIHSGGSHNSNDESTHSLSDASPPAVSFGGLYPSLDAMRNRTNSAPDVSALSGAARRPIAGLPRTSMGNAHNTSTNQSTKPSYLSGMFGHSSSQQYDGTTHNYLHGLSNEHHNDYSHSANNGATNAYASFDSLARNKQSFPAATLAPKMFHNKVYRDVAPLGTAVSKRARESAERTNVEDSDREELYADQESNHGYAVSNERAREERTPKIPVRSLIASIRTLSPSTAADGEDDLKLPAISPSHVEPGTDLPPLYSIQRGGHSSGQYRRASSLSSNSTSTSGSSSFNSSLAPSNVASGTTTPRGSTPPRGVPTKRHTEDEIVRGVKRLELGPAEPLRSTTPELPDSGTTEQALERDQKPDISALSLSSSPTPPSNNPPPSVSTANEEGKDMTIEEMRRRHAALIKSWLVAVNLQWRRKKMEEMQRQQREEMEELEEGGEAMNVDERERERVEVVA
What is the function of this protein?
Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH.  At alkaline ambient pH, activates transcription of alkaline-expressed genes (including RIM101 itself) and represses transcription of acid-expressed genes (By similarity).
What are the official names of this protein?
pH-response transcription factor pacC/RIM101.
What is the protein family that this protein belongs to?
Belongs to the pacC/RIM101 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.