PharMolix/UniProtQA huggingface dataset:
Protein: YH7G_SCHPO
Sequence: MSSGDVSRRQRVSRACDECHRRKIKCDQRRPCSNCIAYNYECTYGQPFKRLRHAPEKYIEFLELRLKYLRGLAEESDPNLKLPSFLAPPNDKDSPVNQSPWKRSDSSKRSSSQDEFESLFDRYGQLSLKDDGKADFRGSSSGFVFMKNIHQNIARNSTVPNPVQESNSSSSQPDPLSFPYLPPTPAEDEHKKPPLKIQLPPYEEALSIVSQFFMNDHFLVHIHHPASFFEKMHMYYKTGKTDNNFHFLLVATLCLGYTYMPDESPSANYPYHEAYEYYYYIRSSFSWEDSYTIEVVQILLSVALFALFSSRLSQAYTFTNNALLCCHELGLHKDFSDVLTSHESRLSKRVFYSVYVLACYTSTIVGLPLSIEDVDIDQSLPNSFDFTLENDQVPPRLIASECTSLEVFIQHITLSRILSHFVRKVYPVKSPSDSHCKVSLPAVRDHEEKLTYWWKNLPSYLKMSEVPKFSPKWIQAIILELKFRQIELIFYRPFIHSISTPIDNQNGSPMKPANFALKCAQSAERVVFLLQELAKSPNTPKLFFNLYSGYYALMTLTYCATLTKDDANKSNNFITKARLGFHCLQMIYRESTYYSTIMEAIKNLLIAYDMNSSGTENLDATPDVTGQLPNNFSQRTSNIPREFPQAQIFYSDAPYPGYYNPAQFQNAPTNFPMPTYGGRTQDQSYPRQNGYPSYSDGNVYPHDRVMINYGSSMPTANGFYVPNTYSPVPFPYNTSYPPYMSPTSNMPQAFQAYSQYPYQHPPFPLSEQMLPLPTSGVMMAPGAAKSGMPYPFIQPPSMTNQVAYPTVRDGSNNSPDHPSSSNSKRTE
What are the official names of this protein?
Putative transcriptional regulatory protein C16G5.16.
What is the protein family that this protein belongs to?
Belongs to the ASG1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y4289_VIBVY
Sequence: MELKIDTHSHTYASGHAYSTLIENARSAKENGLAMFCTTDHAESMPGAPHYWFFANQRVLPRFLEGVAILRGVEANILNTEGEIDLPLSVDPNLDWAIASFHEPVFAPSNKEAHTQALLNVIQGGRIDALGHLGNPHFDFDFHAVLHCAKEHNVAIEINNSTLKGHSRVGSVERCYEIARVGKALGVYFTTGSDAHFCQDVGKLDLASELLDSVGIDSHRVITHSPSQFLDFLELRGRGPIDELASLRQ
What are the official names of this protein?
Probable phosphatase VVA0289.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: PKS1_ZYMTI
Sequence: MSNILLFGDQTAEQYPLLHRIVLRKDNVLLLSFVERCALALREETRTLSRSQREVMPDFLTLSNLIEAYYQKGEKVLMLESAFLTIAQLGHYIGYFSENPSELPAVSDTRVLGLCTGLLAASAVVSAKTVEELAIVGVDFVRIAFRSGAVVDNVRSMLGQSSQDKSTWSTIISGPSEVDVKDALTSFHEASGIPRSNQAYVSAVSTMALTVSGPPITVERFFQESSLIINHRVSIPIYGPYHAGHLFGEAECERILSGEVGQELRKHMPASLVHSAATGKPIVSENAYELAKLALGEIHQYPVRWDYLLEETVAQIGHYPCGAKIFALGASNIATSLSSALKAGGQADVMIVDEASFVETKKYTGRTQTDKIAIVGMAGRFPNSANHEALWDLLMKGLDVHRKVPADRFDADAHCDPSGKGKNKSHTPFGCFIDEPGLFDPRFFNMSPREAAQTDPMGRLALVTAYEALEMSGYVPNRSTSTKLNRIGTFYGQTSDDWREINAAENVDTYYITGGVRAFAPGRINYYFKFSGPSYSIDTACSSSLAAIQLACTSLWAGDCDTACAGGLNVLTNPDIFSGLSKGQFLSKTGGCKTYDNDADGYCRGDACGTVILKRYQDAVADKDNILGCILGAATNHSAEAVSITHPHAGAQEFLYKQVLANAGIDAHEISYVEMHGTGTQAGDGIEMTSVTNVFAPRRRQRKPEQTVHLGAIKANVGHAEAASGINSLVKVLMMMKNNKIPANVGVKGELNKTFPADLKDRNVHISLKQVDWPRKTEAPRKVFLNNFSAAGGNTALLIEDGPVHKMPNGVDPRSTLPITVTARSIGSLKRNLMNLQKYVAENGSTTLPSFSYTLTARRIQHNYRVAFPLADISKVADALEAQAKDSYSPVPMVTTKTAFCFTGQGSQYTGLGQKLYQDLKSFRDDIDQLDQMARIQGLPSFLELLDGTDVQTLSPVKVQLGMACIQVALSRMWASWGVTPTAVIGHSLGEYAALHVAGVISASDMVLLVGRRAELLVRECTPHTHGMLAVKGGVEAIRNALGINMTEIACINGPEETVLCGSSDVVAAANDTLGKNGFKATKLNVPFAFHSAQVDPILDEFRKVASSVTFNKPSVPILSPLVGIVIRDGGIITADYLARHARETVNFSSALLSGQKEAVFDEKTAWLEVGAHPVCSGMVKASIGTTITAPSLRRGEDAWKTISTSICHLFTAGVNFNFDEFHREFNDAQELLTLPTYSFDNKKYWLDYHNNWTLTKGEVQKTKEVIVEKEIVAPVIEVPAKRLSTSCQNVISEEFDGNRATVVIRSNLADSKLYPVVCGHMVNNAALCPSSLYADMALTVGDYIYKELQPGVETPGMNVCNMEVPKPFIANIPQPAEGQHLEMEATADLDLGTVSLKFRSVHPDGKKIQDHAFCTIRYEDKAVWASEWTRYNYMVKAQIDMLTARTMTGGAHKVQRGMAYKLFKALVNYDDKYRAMAEVVLDGANTEASAAIDFPTKPDDGDFYCPPYHIDGACHISGFIVNASDLLDSEQNVYVSHGWGAMKFSRPLVAGMKLRNYVRMVPQPNNISKGDVYIMEGDEIVAVCEGIKFQQIPRKVLNVFLPPNKGSAVQAKPSPIAQRPAPVRASVAAPVKRMLAPAPVRKSAGPAKAAAAPSMPKPSKVAAKKPAGSMVDKVLTILSKETEVDVAELVDDAHFENLGVDSLLSLTISAIFREDLSMEISPSLFTDYPTVGEMKKYFSQFNNVESTTESEDDSDTDSLATTDVATPFDEMSTPASSAPSVPQSDAGKPSPDSPTGDSLSDDVGDVSIARHIIAQEMGVDISEVTDDAELAEMGMDSLMSLTILGELREKTGIDLPGTFLMTNPTLVDIENALGMRPKPKAVGPKLSKPSTKTDMNEVSSRLTAINKTDISQYPSATSVLLQGNPKTATKKVFFLPDGSGSATSYVSIPNIGPHVAAFGLNCPFMKDPEQWQCGIEVSSLIYLAEIRRRQPKGPYIIGGWSAGGVIAYAVAQALLAAGEKVEKLLLLDSPCPVNLAPLPTRLHVFFNEIGLLGTGDPAKTPKWLLPHFSAAIRSLSAYDPKPTIAELPTYAVWCKDGVAGNPGDPRPPPAEEEDPAPMKWLLNHRTDFSDNGWAQLCGQNMKFGVMGGHHFSMMKDPHASELGQLIKEGIEWKA
What is the function of this protein?
Non-reducing polyketide synthase; part of the gene cluster 29 that mediates the biosynthesis of mediates the biosynthesis of dihydroxynaphthalene (DHN)-melanin, a bluish-green pigment and a structural component of the conidial wall (PubMed:25360032, PubMed:28818040).  The first step of the pathway is the production of the heptaketide naphtopyrone YWA1 by the polyketide synthase PKS1 though condensation of acetyl-CoA with malonyl-CoA (By similarity).
What are the official names of this protein?
Non-reducing polyketide synthase PKS1, Conidial pigment biosynthesis cluster 29 protein PKS1.
Protein: PSBJ_GRATL
Sequence: MAGTGRVPLWLVATVGGIAVITVLGIFIYGSYSGIGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CSP_PLABR
Sequence: MKKLSVLAISSFLIVDFLFPGYHHNSNSTKSRNLSELCYNNVDTKLFNELEVRYSTNQDHFYNYNKTIRLLNENNNEKDGNVTNERKKKPTKAVENKLKQPPGDDDDAGNDEGNDAGNDAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNDAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNDAGNAAGNAAGNAAGNAAGNAAGNAAGNDAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNDAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNEKAKNKDNKVDANTNKKDNQEENNDSSNGPSEEHIKNYLESIRNSITEEWSPCSVTCGSGIRARRKVDAKNKKPAELVLSDLETEICSLDKCSSIFNVVSNSLGIVLVLVLILFH
What is the function of this protein?
In the vertebrate host, binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes and is required for sporozoite invasion of the host hepatocytes.
What are the official names of this protein?
Circumsporozoite protein, CS.
What is the protein family that this protein belongs to?
Belongs to the plasmodium circumsporozoite protein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Cytoplasm. Note=Localizes to the cytoplasm and the cell membrane in oocysts at day 6 post infection and then gradually distributes over the entire cell surface of the sporoblast and the budding sporozoites.
Protein: SSB2_STRA5
Sequence: MYNKVIMIGRLTAKPEMVKTPTDKSVTRATVAVNRRFKGSNGEREADFINVVMWGRLAETLASYGTKGSLISIDGELRTRKYEKDGQTHYITEVLASSFQLLESRAQRAMRENNVSGDLSDLVLEEEELPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein 2, SSB 2.
Protein: PSBH_PORPU
Sequence: MALRTRLGEILRPLNSEYGKVAPGWGTTPIMGIFMLLFFLFLLIILQIYNSSLVLENVDVDWATLGS
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RS7_DANRE
Sequence: MFSTSAKIVKPNGEKPDEFESGISQALLELEMNSDLKAQLRELHITAAKEIEVGGSRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTNVHDAILEDLVFPSEIVGKRIRVKLDSSRLIKVHLDKAQQNNVEHKVETFAGVYKKLTGKDVIFEFPEFQL
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Required for rRNA maturation.
What are the official names of this protein?
40S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS7 family.
Protein: SYE_ECOHS
Sequence: MKIKTRFAPSPTGYLHVGGARTALYSWLFARNHGGEFVLRIEDTDLERSTPEAIEAIMDGMNWLSLEWDEGPYYQTKRFDRYNAVIDQMLEEGTAYKCYCSKERLEALREEQMAKGEKPRYDGRCRHSHEHHADDEPCVVRFANPQEGSVVFDDQIRGPIEFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALKAPVPVYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSHGDQEIFTREEMIKYFTLNAVSKSASAFNTDKLLWLNHHYINALPPEYVATHLQWHIEQENIDTRNGPQLADLVKLLGERCKTLKEMAQSCRYFYEDFAEFDADAAKKHLRPVARQPLEVVRDKLAAITDWTAENVHHAIQATADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGKTRSIERINKALDFIAERENQQ
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KIBRA_XENTR
Sequence: MIRKELPLPEGWEEARDVDGKVYYIDHTSKTTSWIDPRDRFTKPLTFADCIGDELPLGWEESYDTQVGVYYIDHNSQTTQIEDPRVQWRREQERMLKDYLVLAQEALLAQKEIYQVKQQRLELAQKEYRTLNDVWKHKVGSQTSLVSGSSSSSKYDPDILKAEIATTKSRVNKLKREMVFLRQELQYKENGYQTLKEIDLKMSKNHCAYKLDEAQAILNEMKTIKKAITSGEREKQDLIQSLAELKNGFLVDKGSQSDLWASNTSLASSANSLSRQYLNVSSQTDISGNLSVVSNNHLAEKVRLQLRYEEAKRRIANIKIQLAKIDSDAWPGVLDSERDRLILISEKEELLKEMRFISPRKWSQSEVERLESEKKQLEEDLQAARDTQSKALTERLKMSSKRNQLVKELEETTRLIASLQAQLKCLSTSMQSLSSGSSPGSLASSRGSLVTSSQDSSTSASVSDLYYEQLDHLDSEYQNKVDFLIQEGAMGYRPSGCITTIHENEVVRSQKTDPANRVKALRSLSGTPKSMTSLSPRSSLSSPSPPCSPLVTDPLLTVDAFLSQIDFEDIDLPLSFTELNVNAGGDSYQHETDEEPSGQGLSCLGVSSLSVAGVSAAVSDESVTGDSGVYEATNQRTLMENAVFDGEDSEMMDTAKIKIGMKYDEKNKHFAVFVIQLDNLAALLLHQNEKLYIRVAVLPCSESTSCLFRTRTLEQSDTLLYNEMFLVSTSHSALRQKTLRVDVCTRQSNHHEECLGGSQISLADVCHSEEQEAHWYNLLSYRYLKRQSKTSKQKISCCEESGIENPDSVSALLKQTAAELEAVRKQIGESTDPPEYIWPEKKDNVPDEDGISENEGEEEFDGDVQCETEESDMQAATDSASVKVDKETNTEGLAMSLSSVRPKDKRAATPMQAPFIRGNTIIRSKTFSPGPQSQYICRLNRSDSESSTLSKKPPFVRNAMERRSVRVKRPSVKSTGSERLIRTSLDLELDLQASRTWHHQLTQEISVLRELKEQLEQAKRLGENELPQRVKDDETFKVMLRQVEKQVQKIEQKYEMQADKMMRAAAKDVHRLRGQSSKEPLEVQSFREKMAFFTRPRMNLPTLTADDV
What is the function of this protein?
May play a role in the regulation of the Hippo signaling pathway.
What are the official names of this protein?
Protein KIBRA, WW domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the WWC family. KIBRA subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: TPMT_SHESR
Sequence: MEPGFWHEKWQQQLIGFHQQDINPFLVKYWQTLALPADAKVFVPLCGKSLDMCFLAEQGHQVIGCELNELAVQQFFEENQLPMKKSAEGEHQHYHTEQVSLYQGDIFTLPQSITAKVSGFYDRAALIAWPESMRTQYAKQLAQLLPSGSVGLLVTLDYPQEALSGPPFAVSPTWVETHLSDDFEIQALACQDVLADNPRFVKKEVPWLNEAVYLLRRK
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD_SACD2
Sequence: MKDDLFIALQRIIPHHAFSRLVGWFAATKIRWIKHLFITKFINAYNVNMAEALEPNPENYANFNDFFVRALKPDARPIASEANAIVSPADGAVSQLGEISGDKIFQAKNHWFSIKELLACDDELAEQFMGGSFATIYLSPSDYHRVHMPAAGLLTQMNYIPGDLFSVNPVTTENVAGLFARNERIAAIFDTEFGPMAVVMVGAMIVASIETVWDGQITPASREVKRNVYSKPREIKLGKGDEMGRFKLGSTAVLLFPKGAIKWKEDIKAETTLRMGEMIAELQTQA
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MOC2B_TAEGU
Sequence: MEEREDAPKDFIKLKSEKLSVGEVSELVVSPYCGAVSLFIGTTRNNFEGKKVIHLEYEAYTSMAETEMKKICRDVRQKWPSVKHIAVHHRLGVVPITEASVIIAVSSPHRAESLEAVMYCINTLKASVPIWKKEIYEDEYSWKENKECFWANSEK
What is the function of this protein?
Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin.  Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
What are the official names of this protein?
Molybdopterin synthase catalytic subunit, Molybdenum cofactor synthesis protein 2 large subunit, Molybdenum cofactor synthesis protein 2B, MOCS2B.
What is the protein family that this protein belongs to?
Belongs to the MoaE family. MOCS2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: BLAC_CITKO
Sequence: MFKKRGRQTVLIAAVLAFFTASSPLLARTQGEPTQVQQKLAALEKQSGGRLGVALINTADRSQILYRGDERFAMCSTSKTMVAAAVLKQSETQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAATLQYSDNTAMNKLLEHLGGTSNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTCPLAMAKSLHKLTLGDALAGAQRAQLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGAGDYGTTNDIAVIWPEDRAPLILVTYFTQPQQDAKGRKDILAAAAKIVTEGL
What are the official names of this protein?
Beta-lactamase, Penicillinase.
What is the protein family that this protein belongs to?
Belongs to the class-A beta-lactamase family.
Protein: PURA_BURPS
Sequence: MSASAVNVTPGRNVVVVGTQWGDEGKGKIVDWLTDHAQGVVRFQGGHNAGHTLIIGGKKTILRLIPSGIMREGVACYIGNGVVLSPEALFKEIGELEEAGLSVRERLFISEATTLILPYHVAIDQAREARRGAGKIGTTGRGIGPAYEDKVGRRALRVQDLFDARTFADRLRENLDFHNFVLTQYLGGAAVDFQATLDTMLGYADRLKPMVTDVSRRLYEENHAGRNLLFEGAQGTLLDIDHGTYPFVTSSNCVAGAAAAGAGVGPQKLDYILGITKAYCTRVGSGPFPSELYDADNPSRQDQIGITLANVGKEFGSVTGRPRRTGWLDAAALRRSIQINGVSGLCMTKLDVLDGLDEVKLCVGYKIDGEDVDLLPRGAAEVARCEPVYETFGGWKESTVGIDSWDALPANARAYLTRVQEVAGVPIDMVSTGPDRDETILLRHPFKV
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUED_BUCAP
Sequence: MKTIIFKDFQFEAAHYLPYVPKMHKCRRLHGHSFFVRLELKDKINEKNGWIIDYAEIKLAFQPIYDQLDHHFLNDIPGLENPTSEILAKWIWHRLKPKLSILNTIIIKETCTSGCIYQGF
What is the function of this protein?
Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.
What are the official names of this protein?
6-carboxy-5,6,7,8-tetrahydropterin synthase, CPH4 synthase, Queuosine biosynthesis protein QueD.
What is the protein family that this protein belongs to?
Belongs to the PTPS family. QueD subfamily.
Protein: GCSPA_SULIY
Sequence: MYKHPWLPNLDLIDEMLKEIGVNSLDELFNDIPAEIKINRLLNVAKGKPLSEYEIEKEINEKVKKNVELQAPPFIGAGICPHYIPNVVKFIIGRSEFYTSYTPYQPEISQGLLQALFEYQSLMAELLDMDVVNASMYDWGSALAEAVLMANRINGKKTVLVPENANPFHKEVVRTWIGGKGIKIEEVKYDKNSGELDLEDLEKKSNIDDISAIYIQQPNFFGIFESNIEHVIDVAKHKRALSIVGVNPLSLGLIKPPGSYEADIVVGDGQELGLPLNFGGPLMGVFAVRWDMSLVRQMPGRIVGITKDTNGKMGFTLILQTREQFIKREKATSNITTNEALLAIANAVYLSLLGKEGMRELTEEIYFRSHYAAKKLTEIDNVSMPFRSDFFEEFAIRFPIEYDKISNKLKERKLQGGLKLSDYTSLFCVTEVHDKKSIDLLVSTIQEMINGVETS
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: TDCD_ENT38
Sequence: MIEFPVVLVINCGSSSVKFSVLDAASCEALITGIADGVNTENAFISVNGGEPAPLARKDYEGALAAIALELEARDLMGSVALIGHRIAHGGSVFSESTPITDEVIDQIREISPLAPLHNYANLSGVEAAKHLFPGVQQVAVFDTSFHQTLAPQAYLYGLPYRYFEELGVRRYGFHGTSHRYVAQQAYSLLDIPQQDSGLVIAHLGNGASICAVRNGESVDTSMGMTPLEGLVMGTRCGDVDFGAMAWIAQQTGQTLDDLERVVNKESGLLGISGLSSDLRTLEKAWHDGHERARLAIETFVHRIARHIAGHAASLHRLDGVVFTGGIGENSKLIRQLVTDRLKVFGITLDPLKNALPGSAGERIITTDDSDVPCAVIPTNEEKMIALDAIRLGKVHPAAAYA
What is the function of this protein?
Catalyzes the conversion of propionyl phosphate and ADP to propionate and ATP.
What are the official names of this protein?
Propionate kinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family. TdcD subfamily.
Protein: PA2H_DEIAC
Sequence: MRALWIVAVLLVGVEGSLFELGKMIWQETGKNPVKNYGLYGCNCGVGGRGEPLDATDRCCFVHKCCYKKLTDCDSKKDRYSYKWKNKAIVCGKNQPCMQEMCECDKAFAICLRENLDTYNKSFRYHLKPSCKKTSEQC
What is the function of this protein?
Snake venom phospholipase A2 homolog that lacks enzymatic activity (PubMed:10930841).  Is myotoxic (By similarity).  Has a strong indirect hemolytic activity and anticoagulant activity (PubMed:10930841).  A model of myotoxic mechanism has been proposed: an apo Lys49-PLA2 is activated by the entrance of a hydrophobic molecule (e. g.  fatty acid) at the hydrophobic channel of the protein leading to a reorientation of a monomer (By similarity).  This reorientation causes a transition between 'inactive' to 'active' states, causing alignment of C-terminal and membrane-docking sites (MDoS) side-by-side and putting the membrane-disruption sites (MDiS) in the same plane, exposed to solvent and in a symmetric position for both monomers (By similarity).  The MDoS region stabilizes the toxin on membrane by the interaction of charged residues with phospholipid head groups (By similarity).  Subsequently, the MDiS region destabilizes the membrane with penetration of hydrophobic residues (By similarity).  This insertion causes a disorganization of the membrane, allowing an uncontrolled influx of ions (i. e.  calcium and sodium), and eventually triggering irreversible intracellular alterations and cell death (By similarity).
What are the official names of this protein?
Basic phospholipase A2 homolog acutohaemolysin, svPLA2 homolog, Dac-K49.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. K49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PGLR_GOSBA
Sequence: MAPHLNIVPSMFVLLLLFISASKVQPDAFDVVAKFGAKADGKTDLSKPFLDAWKEACASVTPSTVVIPKGTYLLSKVNLEGPCKAPIEINVQGTIQAPADPSAFKDPNWVRFYSVENFKMFGGGIFDGQGSIAYEKNTCENREFRSKLPVNIRFDFVTNALIQDITSKDSKLFHINVFACKNITLERLKIEAPDESPNTDGIHMGKSEGVNIIASDIKTGDDCISIGDGTKNMVIKEITCGPGHGISIGSLGKFQNEEPVEGIKISNCTITNTSNGARIKTWPGEHGGAVSEIHFEDITMNNVSSPILIDQQYCPWNKCKKNEESKVKLSNISFKNIRGTSALPEAIKFICSGSSPCQNVELADIDIQHNGAEPATSQCLNVKPITIGKLNPIPCSGPVPKTPSATA
What is the function of this protein?
May function in the depolymerization of the pectin in its walls during pollen tube elongation, or in that of the pistil during pollination.
What are the official names of this protein?
Polygalacturonase, PG, Pectinase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted. Secreted, cell wall.
Protein: RSGA_ECOLI
Sequence: MSKNKLSKGQQRRVNANHQRRLKTSKEKPDYDDNLFGEPDEGIVISRFGMHADVESADGDVHRCNIRRTIRSLVTGDRVVWRPGKPAAEGVNVKGIVEAVHERTSVLTRPDFYDGVKPIAANIDQIVIVSAILPELSLNIIDRYLVACETLQIEPIIVLNKIDLLDDEGMAFVNEQMDIYRNIGYRVLMVSSHTQDGLKPLEEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDISDNSGLGQHTTTAARLYHFPHGGDVIDSPGVREFGLWHLEPEQITQGFVEFHDYLGLCKYRDCKHDTDPGCAIREAVEEGKIAETRFENYHRILESMAQVKTRKNFSDTDD
What is the function of this protein?
One of at least 4 proteins (Era, RbfA, RimM and RsgA/YjeQ) that assist in the late maturation steps of the functional core of the 30S ribosomal subunit (PubMed:18223068, PubMed:21102555, PubMed:21303937, PubMed:25904134, PubMed:27382067).  Binds the 30S subunit contacting the head, platform, and rRNA helix 44, which may assist the last maturation stages (PubMed:21788480, PubMed:21960487).  Removes RbfA from mature, but not immature 30S ribosomes in a GTP-dependent manner; 95% removal in the presence of GTP, 90% removal in GMP-PNP and 65% removal in the presence of GDP (PubMed:21102555, PubMed:25904134).  Circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (PubMed:12220175).  Dispensible for viability, but important for overall fitness.  The intrinsic GTPase activity is stimulated by the presence of 30S (160-fold increase in kcat) or 70S (96-fold increase in kcat) ribosomes (PubMed:14973029).  Mature 30S ribosomes stimulate intrinsic GTPase more than do immature 30S ribosomes (PubMed:25904134).  Ribosome-associated GTPase activity is stimulated by RbfA (PubMed:21102555).  The GTPase is inhibited by aminoglycoside antibiotics such as neomycin and paromycin (PubMed:15466596) streptomycin and spectinomycin (PubMed:15828870).  This inhibition is not due to competition for binding sites on the 30S or 70S ribosome (PubMed:15828870).
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associates with 30S ribosomes (PubMed:14973029).
Protein: PB1F2_I80A8
Sequence: MEREQDTPWTQSTEHINIQKRGNGQQTQKLEHPNLTQLMDHYLRIMSQVDMHKQTVSWKQWLSLKSPTQESLKTRVLKRWKLFNKQEWTS
What is the function of this protein?
Plays an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.  Promotes alteration of mitochondrial morphology, dissipation of mitochondrial membrane potential, and cell death.  Alternatively, inhibits the production of interferon in the infected cell at the level of host mitochondrial antiviral signaling MAVS.  Its level of expression differs greatly depending on which cell type is infected, in a manner that is independent of the levels of expression of other viral proteins.  Monocytic cells are more affected than epithelial cells.  Seems to disable virus-infected monocytes or other host innate immune cells.  During early stage of infection, predisposes the mitochondria to permeability transition through interaction with host SLC25A6/ANT3 and VDAC1.  These proteins participate in the formation of the permeability transition pore complex (PTPC) responsible of the release of mitochondrial products that triggers apoptosis.
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
What are the subcellular locations of this protein?
Host mitochondrion inner membrane. Host nucleus. Host cytoplasm, host cytosol. Note=Inner mitochondrial membrane in most cells types. Otherwise is detected in the nucleus and cytosol.
Protein: H2B_ASTRU
Sequence: MPPKPSGKGQKKAGKAKGAPRTDKKRRRKRKESYGIYIYKVMKQVHPDTGISSRAMSIMNSFVNDIFERIAAEASRLAHYNKKSTITSREVQTAVRLLLPGELAKHAVSEGTKAVTKYTTSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B, gonadal.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.