PharMolix/UniProtQA huggingface dataset:
Protein: Y2016_DICDI
Sequence: MFSSITSKLSAISGGSSKNDYKEANYYNYFRILEKKQTEEIARKRCGLYSLKNHNNVFVLKEFSIETEINDCSSTSIWTQSYSNDSNTPVEAKYQLPLHPTSVVSNFQIEYQGKVIQGKIKEKEKALEKYNDAIASGGQAFMATKSDDGYFNLTLGNLPPKENVKVRVVISSELGTHTDGQLHYCLHRYMFPSYAFNFNYNVVLKFSIPIKSIDCDGFDVNVNYKENSSKKEAKITSKSQHTSGVKKNIILIIQPVELNEPKSMIEYIGGGDDKSYATAINFYPSFKNVNPDEVYQKSEFIFLIDCSGSMSGQSINKARRAMEIIIRSLNEQHKVNIYCFGSSFNKVFDKSRVYNDETLEIAGSFVEKISANLGGTELLPPMVDILSSPNDPEYPRQVFILTDGEISERDKLIDYVAKEANTTRIFTYGIGASVDQELVIGLSKACKGYYEMIKETTNMEKQVMKLLNVAFEPMLSNIKLDWSSCGLVDVIQAPSHIRPLFNQERMMIYSMIPSNQTNQDIINASIETSKPLIITLTGDGPKGNVLSFPITLDFKNDLSTNSNQIHTLAAFKHIQDLEESERKEKKDNKDKIVELGKKYGLVSKHTSYIVTADSDNVTEETMKTVDIMNQSPPIRPGGRIVSRGGGRSGASGALSSSILSRKRSSSPSTATKRSSSSSFSSSYLSLSSSSQKKKKEVSRSDDDDDDEKIENCVESYESDGGDQSSEQDEEEEDDCDDFHEDLDEDLGATAMDVDKKECEKECKKKDSSKVDLKVKPSKVPLPSRSPSVSKPTTTSLLSPSPKSAPSAPSQQKSVKSTGDLLIDLLKIQKSNGSWTKSSIDQLKIPTDKAPAELSTTELNDIWVTIIVIAKIVKFFSSEKAQYELAIQKSTRWVKLQLSKLNLPENTFDKFLSNAKSLV
What are the official names of this protein?
von Willebrand factor A domain-containing protein DDB_G0292016.
Protein: FLAV_AZOVI
Sequence: MAKIGLFFGSNTGKTRKVAKSIKKRFDDETMSDALNVNRVSAEDFAQYQFLILGTPTLGEGELPGLSSDCENESWEEFLPKIEGLDFSGKTVALFGLGDQVGYPENYLDALGELYSFFKDRGAKIVGSWSTDGYEFESSEAVVDGKFVGLALDLDNQSGKTDERVAAWLAQIAPEFGLSL
What is the function of this protein?
Flavodoxins are low-potential electron donors to a number of redox enzymes.  NifF is the electron donor to nitrogenase, and is thus implicated in nitrogen fixation.  Does not function as an electron donor to nitrite reductase.
What are the official names of this protein?
Flavodoxin 2, AvFld 2, Flavodoxin II.
What is the protein family that this protein belongs to?
Belongs to the flavodoxin family.
Protein: MTNA_STUS1
Sequence: MRERLLAAEKVKSIEWHGDRLSLLDQRKLPTEEVWHSCDSAAAVADAIRDMVVRGAPAIGISAAYALVLAARTRMAAGGDWRQALEEDVALLAASRPTAVNLFWALNQMRERLERLKPGEDPCAALEAQAISIHESDREANLAMAQFGVDLIRRHQGNPQNLLTHCNTGALATGGFGTALGVIRAAHLDGLVERVYVDETRPWLQGSRLTAWELLGDGVPATLNVDSAAAHLMKSRGISWVIVGADRITANGDVANKIGTYQLAVLAMHHGVRFMVVAPSSTIDMALESGDEILLEERAGSELLEVNGQRFAAEIEVFNPVFDVTPADLIDAIVTEKGVVERPNAAKMTELMNRKRLH
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: CSPLF_ORYSJ
Sequence: MCEGEKKKDSSSGALYCVNLALRIVVLGLAVAAAALMATASQCTIFLYYGGPLHTITYKDFGPFVYLVVASSIGAFMEAIAIFLTICKKKDGTPAKVLLPLLDAAVPVLLYSATAAAFAAGDMSYCAVGKRVGVCTTAAAGNFCNQVHIAMYVSLAAGVALLVAEIVKHWPDSGKKKEGGGGGCGSDSDSDKSTPCHHGCHSKH
What are the official names of this protein?
CASP-like protein 1U3, OsCASPL1U3.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2990_BRUA2
Sequence: MQNRTLPYFLILPSLLLAAVVIFWPVVHLFEIATHDVNRFGQLREFNDGANFTALFATAEFMNALWRTAVWTVAVVGGALVLSIPVAIILNMDFYGRSVARVIIMLPWAVSLTMTAIFWRWALNGESGMLNSALHGLGLIDTNIQWLASAATAFPMQILVGILVTVPFTTTIFLGGLSSIPDDLYEASSLEGASLWQQFREITFPLLKPFVNIAIVLNTIYVFNSFPIIWVMTQGRPANSTDILVTHLYKLAFRLGKFGEASAVSLIMLAILLVFTVIYIRISTRSEQS
What is the function of this protein?
Probably part of an ABC transporter complex.  Probably responsible for the translocation of the substrate across the membrane (Probable).
What are the official names of this protein?
Probable ABC transporter permease protein BAB2_0490.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y5156_BACCR
Sequence: MTENNDIKMVIITGMSGAGKTVALQSFEDLGYFCVDNLPPMLLPKFIELMADSKGKMNKVALGIDLRGREFFEHLWGALDDLSERTWIIPHILFLDAKDSTLVTRYKETRRSHPLAPTGLPLKGIEAERNLLTDMKARANIVLDTSDLKPKELREKIVHLFSTETEQAFRVNVMSFGFKYGIPIDADLVFDVRFLPNPYYIPHMKPLTGLDEEVSSYVLKFNETHKFLEKLTDLITFMLPHYKREGKSQLVIAIGCTGGQHRSVTLTEYLGKHLKPEYSVHVSHRDVEKRKGH
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein BC_5156.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: TNSB_ECOLX
Sequence: MWQINEVVLFDNDPYRILAIEDGQVVWMQISADKGVPQARAELLLMQYLDEGRLVRTDDPYVHLDLEEPSVDSVSFQKREEDYRKILPIINSKDRFDPKVRSELVEHVVQEHKVTKATVYKLLRRYWQRGQTPNALIPDYKNSGAPGERRSATGTAKIGRAREYGKGEGTKVTPEIERLFRLTIEKHLLNQKGTKTTVAYRRFVDLFAQYFPRIPQEDYPTLRQFRYFYDREYPKAQRLKSRVKAGVYKKDVRPLSSTATSQALGPGSRYEIDATIADIYLVDHHDRQKIIGRPTLYIVIDVFSRMITGFYIGFENPSYVVAMQAFVNACSDKTAICAQHDIEISSSDWPCVGLPDVLLADRGELMSHQVEALVSSFNVRVESAPPRRGDAKGIVESTFRTLQAEFKSFAPGIVEGSRIKSHGETDYRLDASLSVFEFTQIILRTILFRNNHLVMDKYDRDADFPTDLPSIPVQLWQWGMQHRTGSLRAVEQEQLRVALLPRRKVSISSFGVNLWGLYYSGSEILREGWLQRSTDIARPQHLEAAYDPVLVDTIYLFPQVGSRVFWRCNLTERSRQFKGLSFWEVWDIQAQEKHNKANAKQDELTKRRELEAFIQQTIQKANKLTPSTTEPKSTRIKQIKTNKKEAVTSERKKRAEHLKPSSSGDEAKVIPFNAVEADDQEDYSLPTYVPELFQDPPEKDES
What is the function of this protein?
Sequence-specific, DNA-binding protein required for Tn7 transposition.  Recognizes sequences necessary for recombination at both left and right ends of Tn7 and, together with TnsA, forms the transposase.  TnsB executes the 5'-DNA strand breakage and joining reactions.
What are the official names of this protein?
Transposon Tn7 transposition protein TnsB.
Protein: PFD4_DROME
Sequence: MAAKVASGTNKVFQNHDDVHISFEDQQRINRFAKHNARMDDFKAELETKRNELKSLEEALEEIELFDEDEDIPFLVGEVFLSHKLEKTQDMLKETKEQVLKEIAGVEAKAKVIKAEMDELKAHLYQRFGSNISLEAED
What is the function of this protein?
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it.  Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity).
What are the official names of this protein?
Probable prefoldin subunit 4.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
Protein: IXTPA_YERPS
Sequence: MQKIVLATGNPGKVRELANLLADFGLDVVAQTELGVESAEETGLTFIENAILKARHAAQTTGLPAIADDSGLAVDALGGAPGIYSARYAGTDASDQENLEKLLAALQNVPEEKRGAQFHCVLVYMRHAEDPTPLVFHGQWPGVIAHQPAGAAGFGYDPIFYVPALGKTAAELTREEKHAVSHRGQALKLMLDALRDA
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: CAPZB_YEAST
Sequence: MSDAQFDAALDLLRRLNPTTLQENLNNLIELQPNLAQDLLSSVDVPLSTQKDSADSNREYLCCDYNRDIDSFRSPWSNTYYPELSPKDLQDSPFPSAPLRKLEILANDSFDVYRDLYYEGGISSVYLWDLNEEDFNGHDFAGVVLFKKNQSDHSNWDSIHVFEVTTSPSSPDSFNYRVTTTIILHLDKTKTDQNSHMMLSGNLTRQTEKDIAIDMSRPLDVIFTSHVANLGSLIEDIESQMRNLLETVYFEKTRDIFHQTKNAAIASSAEEANKDAQAEVIRGLQSL
What is the function of this protein?
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends.  Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
What are the official names of this protein?
F-actin-capping protein subunit beta.
What is the protein family that this protein belongs to?
Belongs to the F-actin-capping protein beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, actin patch. Bud. Bud tip. Note=Found at cortical actin spots at the site of bud emergence and at the tips of growing buds and shmoos.
Protein: Y1573_ARCFU
Sequence: MRPQQYGGECGMKKKHVILLILILLPVVFLHIMLATWGLSMSFYVKRLSSPPQNYFEITEEDFREIPELKKIFEDLRKLAPGESRSYELDIDTGNKVHSYLTEKQAGVGECSYTYCFKYGDAYYGAHMGTP
What are the official names of this protein?
Uncharacterized protein AF_1573.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DXS_DESAP
Sequence: MGLLDGISHLTDLRALTPDQLDELAAELRDLIVSTVSRTGGHLAPNLGVVELTLALHYVFRAPDDRIVWDVGHQCYVHKILTGRKSQFHTLRQFEGLSGFPNRNESEYDCFGTGHSSTSISAALGMALARDLSGEDRNVVAVIGDGALSGGMAFEALNQAGHLGCRLIVVLNDNEMSIARNVGAMARYLSRLRTDPMYSRSKDEVESLLRRIPAIGPRVLGWIERIKDSLKYLVVAGMLFEELGFTYLGPIDGHNIPAMLNVFRQAQAVEGPVLVHVLTKKGKGYAPAEKNPDKFHGVGPFDPATGNTPTDARVSFTEVFGRTLVQLAEADSRILAITAAMTSGTGLGPFSRRFPQRFFDVGIAEQHAVTLAAGLAVEGYRPVVAIYSTFLQRAYDQVLHDVCLQKLPVVFALDRGGIVGEDGVTHQGVFDFSFLRPVPNLVMMAPKDENEFQHMLKTAVEHEGPIAVRYPRGTGTGCALDQDLVALPIGRAEVLREGDDITLIAIGNMVPTAVKAAEILAERGIEASVVNARFVKPLDEKCICHYARRTGRLITLEENVIAGGFGSAVQELLVAKGLTDVRVQLIGLPDVFIEHGAPHLLRAKYGLTVDRVVRTAESEKRKRARLKLAPRLLR
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: SPRT_KLEP3
Sequence: MKTPRIPIAIQQAVMRSLREHLAKANLKLERRYAEPTLVYQQRGTSAGTAWLEKNEIRLNPVLLLENQQEFIDEVVPHELAHLLVWQHFGRVAPHGKEWKWMMENVLGVPARRTHRFELDSVRQNTFPYRCRCQQHQLTVRRHNRVVRGEATYRCVHCGDLLVAEK
What are the official names of this protein?
Protein SprT.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_DROME
Sequence: MAFNKLSIENLDLAGKRVLMRVDFNVPIKEGKITSNQRIVAALDSIKLALSKKAKSVVLMSHLGRPDGNKNIKYTLAPVAAELKTLLGQDVIFLSDCVGSEVEAACKDPAPGSVILLENVRFYVEEEGKGLDASGGKVKADPAKVKEFRASLAKLGDVYVNDAFGTAHRAHSSMMGDGFEQRAAGLLLNKELKYFSQALDKPPNPFLAILGGAKVADKIQLIENLLDKVNEMIIGGGMAFTFLKVLNNMKIGGSLFDEEGSKIVEKLVEKAKKNNVQLHLPVDFVCGDKFAENAAVSEATVEAGIPDGHMGLDVGPKTRELFAAPIARAKLIVWNGPPGVFEFPNFANGTKSIMDGVVAATKNGTVSIIGGGDTASCCAKWNTEALVSHVSTGGGASLELLEGKTLPGVAALTSA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC2_PSEF5
Sequence: MKKTAVIVFSGGQDSTTCLIHALPLYDEVHCITFDYGQRHHAEIETAQRLSKQLGATVHKVLDASLLNELAISSLTRDNIPVPTVNSSGESLPSTFVPGRNILFLTLASIYAYQVKAETVITGVCETDFSGYPDCRDEFVKALNKALELGMEYKLRLETPLMWLNKAETWALADYHNQLELVREQTLTCYNGIMGSGCANCDACNLRAKGLNAYLENKTQVMDSLKSKMGLK
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase 2, 7-cyano-7-carbaguanine synthase 2, PreQ(0) synthase 2, Queuosine biosynthesis protein QueC 2.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RL2_SYNJA
Sequence: MGIRTFRPYTPSTRHMTVSNFEELSRDENGKRPRPEKSLLQFIHRKKGRNNRGVITCRHRGGGHKRLYRIIDFRRDKRGIPATVKTIEYDPNRSARICLVEYEDGEKRYILAPRNLEVGATIMAGPDAPFELGNAMPLERIPLGTVVHNVELYPGRGGQIVRAAGAGAQVVAKEGKYVSLKLPSGEVRMIRGECYATIGQVGNVDHSNLSLGKAGRSRWLGRRPHVRGSVMNPVDHPHGGGEGKAPIGRSTPVTPWGKPTLGYKTRKRNKPSNKFIVRGRRRGGRRDKSGRAAQ
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: DRAM1_MOUSE
Sequence: MLCFLRGMAFVPFLLVTWSSAAFIISYVVAVLSGHVNPFLPYISDTGTTPPESGIFGFMINFSAFLGAATMYTRYKIVEKQNETCYFSTPVFNLVSLALGLVGCIGMGIVANFQELAVPVVHDGGALLAFVCGVVYTLLQSIISYKSCPQWNSLTTCHVRMAISAVSCAAVVPMIACASLISITKLEWNPKEKDYIYHVVSAICEWTVAFGFIFYFLTFIQDFQSVTLRISTEINDDF
What is the function of this protein?
Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis.  Not involved in p73/TP73-mediated autophagy (By similarity).
What are the official names of this protein?
DNA damage-regulated autophagy modulator protein 1, Damage-regulated autophagy modulator.
What is the protein family that this protein belongs to?
Belongs to the DRAM/TMEM150 family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.
Protein: ASNA_STRZP
Sequence: MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGMQDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPDEDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESILPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDYDDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLELEWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_CUSRE
Sequence: MPIGVPRVRFQYRRDRSRVWIDIYNRLYRERCLFLAHVVESQIANQLVGLFIYLGVQDETKDIFLFINSPGGGIISGFAIYDTMQFVRPDIQTICVGLAASMGSFLLVGGAITKRLAFPHARVMIHQPMSAFFETQTVEAILEAEELLKLRESLAKVYVQRTGKPDWVIAEDMERDVFLSATEAQSYGIVDVVGVALASKG
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins (By similarity).
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid.
Protein: MOCS1_BOVIN
Sequence: MAAQPVSRVVRRVLRAGVRSCSSGAPVTQPCPGEPVVEVLSRPRPFLGEHAAPFSAFLTDSFGRHHSYLRISLTERCNLRCQYCMPEEGVPLTPKADLLTTEEILTLARLFVKEGVDKIRLTGGEPLIRPDVVDIVAQLRQLEGLRTIGITTNGINLARLLPQLQKAGLSAINISLDTLVPAKFEFIVRRKGFHKVMEGIHKAIELGYSPVKVNCVVMRGLNEDELLDFVALTEGLPLDVRFIEYMPFDGNKWNFKKMVSYKEMLDTLRQQWPELEKLPEEESSTAKAFKIPGFRGQVSFITSMSEHFCGTCNRLRITADGNLKVCLFGNSEVSLRDHLRAGASEEELLRVIGAAVGRKKRQHAGMFNISQMKNRPMILIELFLMRQDSPPALPSTFRNSLRVQVLRHRVSFSSQMVTLWKGGGVPQAPLVAQRWLGSSLPQRHFSSHLDSDANPKCLSPTEPQAPAASSGPLPDSDQLTHVDTEGRMAMVDVGRKPDTERVAVASAVVLLGPVAFKLIQENQLKKGDALAVAQLAGIQAAKLTSQLIPLCHHVALSHVQVQLELDRTRHAAVIQASCRARGPTGVEMEALTSAAVAALALYDMCKAVSRDIVLAEIKLVSKTGGQRGDFHRT
What is the function of this protein?
Isoform MOCS1A and isoform MOCS1B probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP).  MOCS1A catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate and MOCS1B catalyzes the subsequent conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cPMP.
What are the official names of this protein?
Molybdenum cofactor biosynthesis protein 1.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the radical SAM superfamily. MoaA family.
Protein: AT8B3_MOUSE
Sequence: MDGVHLGENLEDKDTEFTWEVKANDRTYHKQFKKKGFLCWRQKKYKSNAIHTAKYNIFSFLPLNLYEQFHRMSNLYFLFIIILQGIPEISTLPWFTLFAPLVCLFVIRATRDLVDDIGRHRSDKIINNRPCQILRGKSFLWKKWKNLCVGDVVCLSKDSIVPADLLLLASTEPSSLCYVETADIDGETNLKFRQALTVTHHELTSPKKMASFQGTVTCEEPNSRMHHFVGSLEWNSRKYPLDIGNLLLRGCKIRNTDTCYGLVIYAGLDTKIMKNCGKIHLKRTKLDLMMNKLVALIFLSLVIASLLLTVGFTFMVKQFKAKHYYMSPTHGRSDAMESFFIFWGFLILLSVMVPMAMFIIAEFIYLGNSIFINWDLNMYYEPLDMPAKARSTSLNDQLGQVQYIFSDKTGTLTQNIMTFKKCCINGCIYDSDDEHGTLRKRNPYAWNPFADGKLQFYNKELESLVQGRQDRAVQEFWRLLAICHTVMVQEKDNQLLYQAASPDEEALVTAARNFGYVFLSRTQDTITLVELGEERVYQVLAMMDFNSVRKRMSVLVRNPEGSICLYTKGADTVILERLRSKGVMEATTEEVLAAFAEQTLRTLCLAYKDVEEDAYKEWEPEHQEAALLLQNRAQALHQVYNKMEQNLQLLGATAIEDKLQDGVPETIKCLKKGNIKIWVLTGDKPETAVNIGFACQLLSENMIILEDKDINQVLERYWEDNVHQKAFKMMTHHNMALVINGEFLDQLLLSLRKEPRALVQNAVVDEVAQEPVVSALDFLQKRRISQMWRNAGPSLGTSHSADSKIRESPEVQRERAFVDLASKCQAVICCRVTPKQKALVVALVKKYQQVVTLAIGDGANDVNMIKTADIGVGLAGQEGMQAVQNSDYVLAQFCYLQRLLLVHGRWSYMRVCKFLRYFFYKTVASMMAQIWFSLVNGFSAQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVTAEKSLKMPELYMAGQKGELFNYSIFMQAITHGTITSMINFFVTVMVSSDMSKAGSSHDYQSLGVLVAISSLLSVTLEVMLVVKYWTLLFVGAVVLSLSSYVLMTSLTQSLWMYRISPKTFPFLFADYNVLFEPCSLLLIVLNVALNVLPMLALRTIHRTVLKQRPKGEEEAPSEEVAVEPAMRHLRRGIPARRSSYAFSHREGYANLITQGTILRRQTHVDDSDGGTVCESLNPPEEDIPLQNKDSVFNPRKISILAKKRRHFFGKGSQEEVHPNTSSQTMEKQPTIHRDSETQKLPTTTSATSGKLLPSASEDEAFYSVASQYTLASQPKHTDVHSSFWKSPLWRDSASSSPSQLEVPRKQS
What is the function of this protein?
P4-ATPase flippase which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids (PubMed:14975727, PubMed:19017724).  Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (PubMed:14975727).  May be responsible for the maintenance of asymmetric distribution of phosphatidylserine (PS) in spermatozoa membranes (PubMed:14975727).  Involved in acrosome reactions and binding of spermatozoa to zona pellucida (PubMed:19017724).
What are the official names of this protein?
Phospholipid-transporting ATPase IK, ATPase, class I, type 8B, member 3, Sperm aminophospholipid transporter, SAPLT.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TARJ_BACSH
Sequence: MINQTYRLVSARQFEVTYKDKVVHSDKVVVRPTHLSICAADQRYYTGSRGKEAMDKKLPMALIHEGIGKVMFDPTGTFKVGTRVVMVPNTPVEEHEVIAENYLRSSRFRSSGYDGFMQDYMFMAPDRLVELPDSINPHVAAFTELITIAVHALSRFERMAHKKRDTFGVWGDGNLGFIMTLLLKKKYPDSKVFIFGKTPYKLDHFSFVDAAYQINDIPEDVRLDHAFECVGGRGSESAIEQIIAHVHPEACVALLGVSEYPVEIETRMVLEKGITLIGSSRSGREDFARTVDFLAQYPEVVDYLETLVGGRFPVRSIEEITNAFEADLTSSWGKTVIEWEI
What is the function of this protein?
Catalyzes the NADPH dependent reduction of D-ribulose 5-phosphate to D-ribitol 5-phosphate.
What are the official names of this protein?
Ribulose-5-phosphate reductase, Ribulose-5-P reductase, Ribitol-5-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: GLMU_THEM4
Sequence: MKTLILAAGLGKRMNSKYPKVIHKIFNKPMINWVIETAKNFGKVAVVLGHKYELVKKVIPEDVEIYLQNQQLGTAHAVMSAIEFVSPNDNLLILYGDVPFISHETLKRLEKEHVKSNSDVTILTSILENPTGYGRIVRDGKIRIIEDKDATEEVKKIKEINTGIYIIKGNFLIENINKIENNNTQKEYYLTDILKFTDNISTVTTNDVDEITGVNNRIQLANLEKKIRRKINEKLMNQGVRIIDPNAVYIDPQVKIGRDTLIYPFTFIEGETEIGEDCVIGPLTRIKESKIGNKVTINRSEVEKSVIEDNVSVGPFARLREGTTLDENVKIGNFVETKKSSIGKNSKAQHLTYLGDATIGNNVNIGAGTITCNYDGQTKHPTYIEDNAFIGSNNSLVAPVKIGKNAITAAGSTITNNVPENSLAIARQKQINKENWVLRKGGQKNANNKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO5_SACSH
Sequence: MRGSSNRKIDPRIHYLVPKHEVLSIDEAYKILKELGIRPEQLPWIRASDPVARSINAKPGDIIRIIRKSQLYGEVVSYRYVISG
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo5, DNA-directed RNA polymerase subunit H.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y869_LIMRJ
Sequence: MKRVWVTGYRSYELNIFKDNDPKVQVIKEVLKNYLRAQLELNDDEFWVITGPQMGTERWGLEAALELQADFPQLKTALMFPFAEFGKQWNENNQLKLTSITQQVDFFANVSDKPYQSPQQLRNYQQFMLTHTDEAFLLYDPEYQGKTKYDYEIIQKYKEESEYSMTFVDFDELQEEAEEWAERQREKDEF
What are the official names of this protein?
UPF0398 protein LAR_0869.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: AMPA_CHLL3
Sequence: MKTAATFSALQDLDADLLIFPFSSEGLKKAASPVLEAAGLSDAPLDDFKAAAGDTLVLYPRPGKLRAPRVMLVGTGEAGSLDDWHRAATAAASRAVDLEARRIVFDLPAAGGKAKPGIEAVAETLVEGCLFGAYRFERLKSGKLDKGEKKTAAKGKAKKAEKGIDLLTLRVPASALAAAEKGMASGLVIGSAQEMARNLVNLPGNHLQAEDIARAAAASGKQYGYGVTVLRKKEIESLRMGGLVAVNQGSLNPPTFTVMDYVPKKKAKATIALVGKGVTFDSGGISIKPSEGMGDMKSDMAGAAAVIGAVEAAARLALPVRIIGLIPATDNMPDGNAQKPGDVITTYSGITVEVGNTDAEGRLILADALTYAAQKYSPDAIIDLATLTGACIVALGYQVAGLFSNDDALAGAIEGAARDTGEKVWRLPLWELYDEQIKSDVADVSNTGSRGAGTITAAKFLEKFIDGHKKWAHIDIAGPSFPAKGAAKVNGGSGFGVRLLVELLRKWS
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_CROS5
Sequence: MTVRQKKTWSDRFEGSLHPAIVEFNASITFDIELIEYDLTGSIAHAKMLAKTGIISEAEAQKLVNGLEQIRQEYRDGNFTPGIDQEDVHFAVERRLTELVGDVGKKLHTARSRNDQVGTDIRLYLRDQIQQIRSQIQAFQQVLLTHAQENVETLIPGYTHLQRAQPISLAHHLLAYFQMAQRDWERLGEIYQRTNVSPLGCGALAGTTFPIDRHYSAELLGFEEVYGNSLDGVSDRDFAIEFLNAASLIMVHLSRLSEEMILWASQEFGFISLTDSCATGSSIMPQKKNPDVPELVRGKAGRVFGHLQGMLVLMKGLPLAYNKDLQEDKEAIFDGVKTVKGCLEAMTVLLGEGITFRKERLSEAVAEDFSNATDVADYLAAKGVPFREAYNLVGKVVKTSLASGKLLKDLTLEEWQALHPNFEADIYDAIAPKQVVAARNSYGGTGFEQIYQAVERAKQQLELS
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_RHOPB
Sequence: MTATWKGRLGMSVAAVKDLTMTIAYDLKASVRTIPDYPKPGILFRDITTLLGDARSFRCAIDELVQPWAGSKIDKVAGIEARGFIIGGAIAHQVSSGFVPIRKKGKLPHTTVSMSYALEYGSDIIEMHVDAIKPGERVILVDDLIATGGTAEGAIKLLRQTGAEIVAACFIIDLPELGGAAKIRDMGVPVRALMEFEGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.