PharMolix/UniProtQA huggingface dataset:
Protein: STPA_SALTY
Sequence: MNLMLQNLNNIRTLRAMAREFSIDVLEEMLEKFRVVTKERREEEELQQRQLAEKQEKINAFLELMKADGINPEELFAMDSAMPRSAKKRQPRPAKYRFTDFNGEEKTWTGQGRTPKPIAQALAAGKSLDDFLI
What is the function of this protein?
A DNA-binding protein that acts in a fashion similar to H-NS, repressing gene transcription.  A subset of H-NS/StpA-regulated genes require auxillary proteins for repression; these auxillary proteins (Hha and other similar proteins) may also modulate oligomerization of the H-NS/StpA complex (By similarity).
What are the official names of this protein?
DNA-binding protein StpA, H-NS homolog StpA.
What is the protein family that this protein belongs to?
Belongs to the histone-like protein H-NS family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: S29A2_HUMAN
Sequence: MARGDAPRDSYHLVGISFFILGLGTLLPWNFFITAIPYFQARLAGAGNSTARILSTNHTGPEDAFNFNNWVTLLSQLPLLLFTLLNSFLYQCVPETVRILGSLLAILLLFALTAALVKVDMSPGPFFSITMASVCFINSFSAVLQGSLFGQLGTMPSTYSTLFLSGQGLAGIFAALAMLLSMASGVDAETSALGYFITPCVGILMSIVCYLSLPHLKFARYYLANKSSQAQAQELETKAELLQSDENGIPSSPQKVALTLDLDLEKEPESEPDEPQKPGKPSVFTVFQKIWLTALCLVLVFTVTLSVFPAITAMVTSSTSPGKWSQFFNPICCFLLFNIMDWLGRSLTSYFLWPDEDSRLLPLLVCLRFLFVPLFMLCHVPQRSRLPILFPQDAYFITFMLLFAVSNGYLVSLTMCLAPRQVLPHEREVAGALMTFFLALGLSCGASLSFLFKALL
What is the function of this protein?
Mediates equilibrative transport of purine, pyrimidine nucleosides and the purine base hypoxanthine.  Very less sensitive than SLC29A1 to inhibition by nitrobenzylthioinosine (NBMPR), dipyridamole, dilazep and draflazine.
What are the official names of this protein?
Equilibrative nucleoside transporter 2, 36 kDa nucleolar protein HNP36, Delayed-early response protein 12, Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter, Equilibrative NBMPR-insensitive nucleoside transporter, Hydrophobic nucleolar protein, 36 kDa, Nucleoside transporter, ei-type, Solute carrier family 29 member 2.
What is the protein family that this protein belongs to?
Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein. Note=Localized at the basolateral cell membrane in polarized MDCK cells.
Protein: MCES_XENTR
Sequence: MDNILNPEDNVSQTNTETDVTDGPFQYVKEEHSSHKFTASGQNLDSPPKNKKSPLKRKAGEPESPSKRPRLEEGHGSLVVTHYNELPETGLETRSQSRIFHLRNFNNWMKSALIGEFVEKVRQRTRNIAVLDLGCGKGGDLLKWRKGGISKLVCTDIADVSVKQCEERYKDLKRKSRNERVFEAEFLTADSTKELLSEKYNDPEIKFDICSCQFVYHYSFETYEQADMMLRNACERLCPGGFFIGTTPDGFELVKRLEASDTNSFGNDVYTVKFEKKGKYPLFGCKYDFSLEEVVNVPEFLVYFPVLVEMAKKYQMKLIYKKTFREFFEEKVKNDEQKMLLKRMKALEPYPAAPNFKLVSGRTEDYEHAQKLVENGQVKLPLGTLSKSEWEATSIYLLFAFEKQA
What is the function of this protein?
Catalytic subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs.  Binds RNA containing 5'-terminal GpppC.
What are the official names of this protein?
mRNA cap guanine-N7 methyltransferase, RG7MT1, mRNA (guanine-N(7))-methyltransferase, mRNA cap methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUOI_MYCTA
Sequence: MANTDRPALPHKRAVPPSRADSGPRRRRTKLLDAVAGFGVTLGSMFKKTVTEEYPERPGPVAARYHGRHQLNRYPDGLEKCIGCELCAWACPADAIYVEGADNTEEERFSPGERYGRVYQINYLRCIGCGLCIEACPTRALTMTYDYELADDNRADLIYEKDRLLAPLLPEMAAPPHPRTPGATDKDYYLGNVTAEGLRGVRESQTTGDSR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: STIP1_XENLA
Sequence: MEAANALKEKGNKALSAGNLDEAVKCYTEAIKLDPKNHVLYSNRSAAYAKKKEFTKALEDGSKTVELKADWGKGYSRKAAALEFLNRFEEAKKTYEEGLRHEPTNAQLKEGLQNMEARLAEKKFMNPFNSPNLFQKLESDPRTRALLSDPSYKELIEQLRNKPSDLGTKLQDPRVMTTLSVLLGVELGNVDEEEEDTPPPPPPQPKKETKPEPMEEDLPENKKQAQKEKELGNEAYKKKDFETALKHYGQARELDPANMTYITNQAAVYFEMGDYSKCRELCEKAIEVGRENREDYRLIAKAYARIGNSYFKEEKNKEAIQFFNKSLAEHRTPEVLKKCQQAEKILKEQERVAYINPDLALEAKNKGNESFQKGDYPQAMKHYSEAIKRNPNDAKLYSNRAACYTKLLEFLLAVKDCEECIRLEPSFIKGYTRKAAALEAMKDFTKAMDAYQKAMELDSTSKEATDGYQRCMMSQYNRNDNPEDVKRRAMADPEVQQIMSDPAMRLILEQMQKDPQALSDHLKNPVIAQKIQKLMDVGLIAIR
What is the function of this protein?
Acts as a co-chaperone for HSP90AA1 (By similarity).  Mediates the association of the molecular chaperones HSPA8/HSC70 and HSP90 (By similarity).
What are the official names of this protein?
Stress-induced-phosphoprotein 1, STI1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Dynein axonemal particle.
Protein: PDX1_SCHPO
Sequence: MSAEIKGSTQVKAGLAQMLKGGVIMDVVNAEQARIAEAAGACAVMALERVPADIRAQGGVARMSDPSMIKEIQAAVSIPVMAKVRIGHFVEAQILESIGVDYIDESEVLTPADDINHIEKSKFTVPFVCGSRNLGEALRRISEGAAMIRTKGEAGTGDVVEAVRHTRQMQGELRRVKSMSPDELYTYAKEIAAPIDLVKECAQLGRLPVVNFAAGGVATPADAALMMQLGCDGVFVGSGIFLSGDPAKRARAIVRAVTHYNDPKILAEVSENLGAAMVGRSVSSLEEKEKLATRGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by PDX2.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.  Also plays an indirect role in resistance to singlet oxygen-generating photosensitizers.
What are the official names of this protein?
Probable pyridoxal 5'-phosphate synthase subunit PDX1, PLP synthase subunit PDX1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: NOP9_YEAS8
Sequence: MGKTKTRGRRHQDKQRKDEFEPSSNSAKEHIQQEESTYNDEAEIKETQPQMFFGVLDREELEYFKQAESTLQLDAFEAPEEKFQFVTSIIEEAKGKELKLVTSQITSKLMERVILECDETQLKDIFQSFNGVFFGLSCHKYASHVLETLFVRSAALVERELLTPSFDNNEKEGPYVTMENMFLFMLNELKPHLKTMMNHQYASHVLRLLILILSSKTLPNSTKANSTLRSKKSKIARKMIDIKDNDDFNKVYQTPESFKSELRDIITTLYKGFTNGAESRSDISQSTITKFREYSVDKVASPVIQLIIQVEGIFDRDRSFWRLVFNTADEKDPKEESFLEYLLSDPVGSHFLENVIGSARLKYVERLYRLYMKDRIVKLAKRDTTGAFVVRALLEHLKEKDVKQILDAVVPELSMLLNSNMDFGTAIINASNKQGGYLRDDVIAQLIQKYYPEKSDAKNILESCLLLSASTLGNTRDDWPTAEERRRSVFLEQLIDYDDKFLNITIDSMLALPEERLIQMCYHGVFSHVVEHVLQTTRVDIIKRKMLLNILSKESVNLACNVYGSHIMDKLWEFTAKLTLYKERIARALVLETEKVKNSIYGRQVWKNWKLELYVRKMWDWKKLIKEQEFEIFPNSKPLQPKPEKHSRERNNSKEGSAFKKQKHYR
What is the function of this protein?
RNA-binding nucleolar protein required for pre-rRNA processing.  Component of the 90S pre-ribosome involved in production of 18S rRNA and assembly of small ribosomal subunit.  Component of the pre-40S ribosome required for release from the nucleolus (By similarity).
What are the official names of this protein?
Nucleolar protein 9, Pumilio domain-containing protein NOP9.
What is the protein family that this protein belongs to?
Belongs to the NOP9 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: BIOB_COXBR
Sequence: MKGRNWNQASVAKLFELPFFELLYKAYETHRSHFDVRDMELCTLSSIKTGTCPEDCAYCPQSGHYKTDVEREKLINLEAVLEQAKVAKENGARRFCMGAAWRSPPKRELPKVLEMIKSVKALGLETCVTLGMLDQEQALQLKEAGLDFYNHNLDTSPEFYKKIITTRTYQDRMETLKNVRNAGINVCCGGILGMGESRADRIQLLLELYQLPEPPTSIPINQLIPIKGTPLENTKAIDPFEFIKTIAITRLLFPTSVIRLSAGREAMSDELQAWCFMAGANSIFYGDKLLTAKNPGQNRDVNLLKKLGLKVPVLTEEYACY
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: MALG_THELN
Sequence: MREEVLKRILLIIGAILMAIICLFPFIWMIVVSFAEDPTFLGSPLVEYKSTLENYVRVLSDPTLHFPAYLKNSIIIASLVTLTTVSISSLAAYAVSRIEFKGRLLIPIFVLGLSMFPQISLVGYLFKFIEKLGWVNTYQALYFPYVAWTLPLSLWILLSYFSQLPKDLDEAAMIDGASRIKTLTTIILPLSAPALFSTALLVFIAAFNEFMFALLFTTDHRARTVPVGIALFQGVHGEIPWGSVMAASVISTIPLVIMALLFQKYIVSGLTAGALKGE
What is the function of this protein?
Part of the ABC transporter complex MalEFGK involved in trehalose/maltose import.  Responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Trehalose/maltose transport system permease protein MalG.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GCH1_SALTY
Sequence: MPSLSKEAALVHDALVARGLETPLRPPMDELDNETRKSLIAGHMTEIMQLLNLDLSDDSLMETPHRIAKMYVDEIFAGLDYANFPKITLIENKMKVDEMVTVRDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQILTALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRQEFLRAVRHHP
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: ATPB_SORBI
Sequence: MRTNPTTSRPGVSTIEEKSVGRIDQIIGPVLDITFPPGKLPYIYNALIVKSRDTADKQINVTCEVQQLLGNNRVRAVAMSATDGLMRGMEVIDTGTPLSVPVGGATLGRIFNVLGEPIDNLGPVDTSATFPIHRSAPAFIELDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEKNIEESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKKGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLASKGIYPAVDPLDSTSTMLQPRIVGNEHYETAQRVKETLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGNIDEASTKAINLEEESKLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: PLSY_STRGC
Sequence: MINTILGLILAYLLGSIPTGLWIGQIFFKKNLREYGSGNTGTTNTFRILGKTAGTVTFAIDFLKGTLATLLPLFLHINGISPMIFGLIAVLGHTFPIFAEFKGGKAVATSAGVVLGFSPLFFSYLIIIFIVTLYLGSMISLASIVVAGFAIISVLIFPLLGIILPSYDLLFTLIIILLASIILIRHRDNMERIKNKSENLIPWGINITKQVPKK
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FETP_ACISJ
Sequence: MARTVHCIKLGKEAEGLDFAPYPGDLGKRIYDNVSKQAWADWIKHQTMLVNENRLNLADARARQYLARQMENHFFGSGADAAAGYVPPSA
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: UVRC_BORBR
Sequence: MPDDFNLKSFLADLPHLPGVYRHLDAAGEVMYVGKARDLKKRVSSYFQKNLASPRIAQMVAKVASVDVTVTRSEAEALLLENNLIKSLRPRYNILFRDDKSYPYLLITGHAWPRIAYYRGATSKRGQYFGPYPNSWAVRETIQILQKVFRLRTCEDTVFANRSRPCLLHQIGRCSAPCVGVIEAGDYAHDVQRAVRFLNGEAREVMDEIEARMLQASTELRFEEAAVLRDQMGSLSKVLHQQTMENVGGDDTDVIAVASAGGKICVNLAMVRGGRHLGDKPFFPTHAEGEQPAQVLEAFVAQHYADGAMPPVLVCSHALPDSGLVGLLAEQGGTRAARVLTRPQGVRRSWLEQAQKNAEMALARALTESGARAGRTLALAEALDLDTDEESLDALRIECFDISHTAGEATQASCVVFLHHDMQPSLYRRYNIVGITPGDDYAAMRQVLTRRFGKVADGEAPMPGLVLIDGGKGQVEVARQVFVELGLDIQSLVGVAKGEGRKVGLETLVFADGRPPVALGKESAALMLIAQVRDEAHRFAITGMRARRAKTRNVSRLEEIEGIGARRRQRLLARFGGLSGVSSASIEDLASVEGISQELAVRIYDALHG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CZS14_CRUCA
Sequence: GFLDIVLHVGLAAGKAALNAVNEAVNQ
What is the function of this protein?
Has antimicrobial activity.
What are the official names of this protein?
Cruzioseptin-14, CZS-14.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Cruzioseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EFP2_RHILO
Sequence: MVKVIASSLRKGNVVDKDGKLYVILFAENIHPGKGTPVTQLDMRRIGDGVKVSERYRTTEQVERAYVEEREHTFLYADGEGFHFMNPETYDQVAVSEAVVGDAAPYLQEGMPVQVSQFNGIAISLVLPQRATFEVVETEPTTKGQTASSSYKPAVLSNGVRTAVPPHIAPGTRVVVMTADGSYVERAKD
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P 2, EF-P 2.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C3H36_ORYSJ
Sequence: MAGGGRGAGLPAAGEAAKAGRVGVGTTKRARDPSPNSKDPNGVVANLLWRRYSGKVVAEVKASILPYVASTLEAKQVEKGKEEGLTGKTSRERERRKGGFVGVIAAEKKPALQLHGDEKYQKKAGNDPVPPTIDDTSKTGGLHLHGGHVSQSPPDSNALSSQRFGSSSPGGDMKNKTRKRTCTFYAQGRCKNGKSCTFLHEGEVSGSDNQVYGNHGGTGEGSEIQHPSSSKEHQFKNSAGSSQHEIYRTLVHAYGEDNRGLTHPVVKHSCHMLKASHGFKIGGSLTANPTNEVVQLPVVQEKNHEPYFMGHQISLGTNNCLNDMGAYSRLRLDGGKLQFEVAKGDSPRDSHLSRSYLEKNPLKPDYRYQPFDSTISLDPHQYSKKLSAYGGATENLPHKHQEEKSSSHVSYSLNSYTGFRKQGHDSSDFFLVNQSLRATSHHGTLPLHQLTPDKDASHHKGADFDKGGTSRSTLHVSSSSQPVVASAGKLSPIKDEVWITSVPFVPSFNFPDFPGSTSPSKSQYDPLVDSIDPPKVESLNNLKTSNISCSISSQHVDTNVIRGGSLEKPLTFADKLARNVSAKGSNDFGLISYDRGHSSSLDGDNRVKTCERKNDASLNNEKSDFRFHLVEHVKELVKPIWKEGNLSKEAHKLIVKKSVDKIFASLEPNQMPETEKAITTYITASAPKIEKLVKAYVDRYRTS
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 36, OsC3H36.
Protein: RL31_COXBN
Sequence: MKENIHPPYKQIKVTCSCGNTFMTGSTLDRELHLEICSACHPFYTGQQKMVDTAGRVERFRKKYAKRRAANASPEDEKK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: ARCA_MYCMM
Sequence: MVDELGSNSEVGTLKVVILHRPGTELRRLTPRNTDQLLFDGLPWVSRAQEEHDQFAELLRSRGVEVLLLSELLTEALHSGAARMQGVAAAVDSRRLGIPLAQELSAYLRGLDPVRLSHVLTAGMTFNELPADARTDVSLVVRMHHDADFVIEPLPNLLFTRDSSIWIGPRFVIPSLAMRARVREASLTDIIYAHHPRFTGIRRAYESRTAPVEGGDVLLLAPGVVAVGVGERTTPAGAEALARSLFDDDLAHTVLAVPIAQRRAQMHLDTVCTMVDVDKVVMYANVVDELTAFTIERQPDGVTISDAAPFVEAAARAMGIEKLQVIGTGIDPVVAEREQWDDGNNTLALAPGVVVAYERNAQTNARLEAAGIEVLTIGGSELGTGRGGPRCMSCPVARDPLP
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLA1_YEAS7
Sequence: MTVFLGIYRAVYAYEPQTPEELAIQEDDLLYLLQKSDIDDWWTVKKRVIGSDSEEPVGLVPSTYIEEAPVLKKVRAIYDYEQVQNADEELTFHENDVFDVFDDKDADWLLVKSTVSNEFGFIPGNYVEPENGSTSKQEQAAAAAEAPAATPAAAPASAAVLPTNFLPPPQHNDRARMMQSKEDQAPDEDEEGPPPAMPARPTATTETTDATAAAVRSRTRLSYSDNDNDDEEDDYYYNSNSNNVGNHEYNTEYHSWNVTEIEGRKKKKAKLSIGNNKINFIPQKGTPHEWSIDKLVSYDNEKKHMFLEFVDPYRSLELHTGNTTTCEEIMNIIGEYKGASRDPGLREVEMASKSKKRGIVQYDFMAESQDELTIKSGDKVYILDDKKSKDWWMCQLVDSGKSGLVPAQFIEPVRDKKHTESTASGIIKSIKKNFTKSPSRSRSRSRSKSNANASWKDDELQNDVVGSAAGKRSRKSSLSSHKKNSSATKDFPNPKKSRLWVDRSGTFKVDAEFIGCAKGKIHLHKANGVKIAVAADKLSNEDLAYVEKITGFSLEKFKANDGSSSRGTDSRDSERERRRRLKEQEEKERDRRLKERELYELKKARELLDEERSRLQEKELPPIKPPRPTSTTSVPNTTSVPPAESSNNNNSSNKYDWFEFFLNCGVDVSNCQRYTINFDREQLTEDMMPDINNSMLRTLGLREGDIVRVMKHLDKKFGRENIASIPTNATGNMFSQPDGSLNVATSPETSLPQQLLPQTTSPAQTAPSTSAETDDAWTVKPASKSESNLLSKKSEFTGSMQDLLDLQPLEPKKAAASTPEPNLKDLEPVKTGGTTVPAAPVSSAPVSSAPAPLDPFKTGGNNILPLSTGFVMMPMITGGAMLPMQRTGGFVVPQTTFGMQSQVTGGILPVQKTGNGLIPISNTGGAMMPQTTFGAAATVLPLQKTGGGLIPIATTGGAQFPQTSFNVQGQQQLPTGSILPVQKTANGLISANTGVSMPTVQRTGGTMIPQTSFGVSQQLTGGAMMTQPQNTGSAMMPQTSFNAVPQITGGAMMPQTSFNALPQVTGGAMMPLQRTGGALNTFNTGGAMIPQTSFSSQAQNTGGFRPQSQFGLTLQKTGGIAPLNQNQFTGGAMNTLSTGGVLQQQQPQTMNTFNTGGVMQQPQMMTTFNTGGAMQQPQMMNTFNTGGIMQQPQMMNTFNTGGAMQQPQQQALQNQPTGFGFGNGPQQSRQANIFNATASNPFGF
What is the function of this protein?
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis.  The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton.  Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins.  Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
What are the official names of this protein?
Actin cytoskeleton-regulatory complex protein SLA1.
What is the protein family that this protein belongs to?
Belongs to the SLA1 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, actin patch. Note=Cytoplasmic and cortical actin patches.
Protein: PYRC_STRPN
Sequence: MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIASEITEEGAETIDATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVETLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIVKEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMIAYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMNPPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLSLTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRFVDSHFASKAANSPFIGETLKGQVKYTICKGQIVYQA
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: CMTR_MYCTO
Sequence: MLTCEMRESALARLGRALADPTRCRILVALLDGVCYPGQLAAHLGLTRSNVSNHLSCLRGCGLVVATYEGRQVRYALADSHLARALGELVQVVLAVDTDQPCVAERAASGEAVEMTGS
What is the function of this protein?
Metal-responsive transcriptional repressor for the cmt operon.  Binding of cadmium or lead causes the repressor to dissociate from the DNA (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator CmtR.
Protein: MALD1_HUMAN
Sequence: MLPPPPRQPPPQARAARGAVRLQRPFLRSPLGVLRLLQLLAGAAFWITIATSKYQGPVHFALFVSVLFWLLTLGLYFLTLLGKHELVPVLGSRWLMVNVAHDVLAAALYGAATGIMSDQMQRHSYCNLKDYPLPCAYHAFLAAAVCGGVCHGLYLLSALYGCGRRCQGKQEVA
What is the function of this protein?
Microtubule-associated protein that exhibits cell cycle-dependent localization and can inhibit cell proliferation and migration.
What are the official names of this protein?
MARVEL domain-containing protein 1.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasm, cytoskeleton. Nucleus. Note=Observed in the nucleus and at the perinuclear region during interphase, but localizes at the mitotic spindle and midbody at metaphase. A significant fraction of MARVELD1 translocates to the plasma membrane during anaphase or upon microtubule depolymerization (By similarity).
Protein: LLDD_ECOSM
Sequence: MIISAASDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSEVALRQRILKNMSDLSLETTLFNEKLSMPVALAPVGLCGMYARRGEVQAAKAADAHGIPFTLSTVSVCPIEEVAPAIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMRRYLQAVTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLGNNFDPSISWKDLEWIRDFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAFLYALATAGQAGVANLLNLIEKEMKVAMTLTGAKSISEITQDSLVQELSKAPAAALAPMAKGNAA
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y875_RICPR
Sequence: MIRKFLLIILAIFTLWVGGFGYYLYLINSYKLNSNTTNAIIVFADGGHKIETCMALLKAGYAPILFITGIESTERFKNLLMKHNVIEQQVILAPNKIMSEEDNIKEAINFIVTYNLTLITLVEHNYNIPFMLNKLQKAIPSSNNVYIVPYPVFSKPKYDVLLKSYHRYLMSIVN
What are the official names of this protein?
Uncharacterized protein RP875.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PUR7_XYLFA
Sequence: MLTTLLQSDLPGLPLRHCGKVRDVFDIPHKRLPVDTRSGEYLLIVATDRLSAFDVVLPDPIPGKGEILCQISNFWFQKTEHLMPNHLTGINVASVLPDGIDKTLYTQRAVVTKKLKPVRIEAIARGYLIGSGWKDYQRTGKVSGIQLPDGLQEAEKLPDPIFTPSTKAAVGHHDENIDFDTTVKMVGAELAERVRDATLRIYHFAAKYAAECGILLADTKFEFGTDIDGRLYVMDEMLTPDSSRYWPIDEYQVGTSPPSYDKQFVRNYLETLDWDKTAPGPTLPQDIIDRTRAKYTKALQQLAGINID
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: BODG_HUMAN
Sequence: MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDVNIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVENGN
What is the function of this protein?
Catalyzes the formation of L-carnitine from gamma-butyrobetaine.
What are the official names of this protein?
Gamma-butyrobetaine dioxygenase, Gamma-butyrobetaine hydroxylase, Gamma-BBH, Gamma-butyrobetaine,2-oxoglutarate dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-BBH/TMLD family.
What are the subcellular locations of this protein?
Cytoplasm.