PharMolix/UniProtQA huggingface dataset:
Protein: LPFD_SALTY
Sequence: MLKKLIMFTGLLGGSVLFSGQALAAADFGPCTPEGGTHIFSATINKTVSDTSKNTTGATFVDFDSWNLGGTYAMSCECPDDTSLINDTLFKAVVPLAFVTNIESRSYYQINNNIAIASDVLISGGRGEYVNTPFENVGNLTNNRSQCSQNASSKDAIWTSGGKGHLSLYILHPFVGESIIPSTKIMDLFVTKKPSVYGSIPASSVYISGSITVPQGCELSSGSTLEIPFGEFKATDFKDRKGQVAKNATKFTKELQFKCTNISDGVKIFLRIEGMPNANDSNAIDMGNPDIGAVIEGANGKILVPNDASVNQELSVSGLVDDTHRTASTTISAYPISTTGKLPAAGDFEGIATMRIDVE
What are the official names of this protein?
Protein LpfD.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: PL8L1_HUMAN
Sequence: MNWFGSNFFRCPEDLSLLNIYSPLLSHMSSEDEHFISNLRGHVPASAVVKQPVRGASGRTTITAIVQTGGGWSTGLFSVCRDRRICFCGLFCPMCLECDIARHYGECLCWPLLPGSTFALRIGTRERHKIQGTLCEDWLAVHCCWAFSICQVARELKMRTSQVYEICAVPMTKDTLV
What are the official names of this protein?
PLAC8-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the cornifelin family.
Protein: ODBB_MOUSE
Sequence: MAAVAARAGGLLWLRAAGAERRRCGLRCAALVQGFLQPGGEDTAQKRRVAHFTFHPDPESLQYGQTQKMNLFQSITSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRAPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPVEPYKIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAQEKLGVSCEVIDLRTIVPWDVDTVCKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY
What is the function of this protein?
The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
What are the official names of this protein?
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial, Branched-chain alpha-keto acid dehydrogenase E1 component beta chain, BCKDE1B, BCKDH E1-beta.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CSD_MYCGE
Sequence: MSAIKFNPSSFRKNFKWFENNKNWINFDNAATSIALDVVAEASKEYYQYFCVNPHNKNPEINQKLIAIIEETRDLLAKFFNAKKNEIIFTSSATESLNLFAFGLSSLVKSNDEIILKEDEHAANVFPWVNLAKENKAKLKIIKKTPNKSWTDAFLKACTPSTKLLVITATSNLFGNSIDYEKISKHLKKISPNSFIVVDAVQAVPHHKIDITSANIDFLTFSTHKFYGPTGLGIAFIKSELQSRLKPFKLGGDIFKSLDNNFKIIFKEGPSKFEAGTLNIMAIYALNKQLKFMQKEFNFSEMVFYSKQLKNLAYQLLSQNPNIVLANHDQDVPIFAFKHKYINSADLATFLNIKKIIVRQGSICVGKFKNKESFLRVSLLHYNTKEELLYLEKLLKTSKNSIINELIY
What is the function of this protein?
Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
What are the official names of this protein?
Probable cysteine desulfurase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
Protein: TRUA_LEGPL
Sequence: MRIALVVEYDGSQYHGWQAQTGLHTIQQAVEFALSKVADSSISVVCAGRTDTGVHATNQVIHFDCEKDRSIRAWIHGANSFLPKDICVKWGKEMPENFHARYSAVSRRYRYVIYNGAIRPGLLRGNVTWQYRQLDHRLMQQGGQCLLGENDFTSFRSVECQSNTPMRNIHQLQVTRHGDLVVLDITANAFLHHMVRNIAGVLIAVGSGKHPVGWVKDVLNAKDRKLGAETAPSYGLYLVQVTYPKEFGLLQNNPGPLFLWEK
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: TEX55_MOUSE
Sequence: MDEPPDESLNHENTTRAPDNEKNNIEGAGQALHRGSEHAGVGSSEPTGDKVSGQANAGSRQTGRRTSEEAEQRSSQPTEHRLPGHAERRASQQAERRLSERRTSQPPNQQLPSHSERKTSGKIDGQESLLSEQTDQETSEFDDLIPSASTDYLSARSQQQEYNQHGYWTEDSSDPHRLSEDLEKDYTRVKHITEKQAGYRSYYKTLAHIESRTLTDTNDYRETGQRLQPCTFEDSEAELPSKVSTTEETESATTIQAYNTQDTELTTSTSHEKLPSITTKVYYSSSPEKIQTTEYTSDTTPVFDQGRSSQRSSQSSRWRFPPIVFEDPYHVALRYVEKHNILHIFQQITENLVYERPDDPLYFMLDQVQNMIKHRDERQSD
What are the official names of this protein?
Testis-specific expressed protein 55, Testis-specific conserved, cAMP-dependent type II PK-anchoring protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: TOLB_LEGPL
Sequence: MFNRIISLFLLLFTGQVIALDLELTQGINSALPIAINSFGSDAAAQEIGNVIENDLTISGQFKIISGPQGANSQSSVSTLRQLGADSVVTGRVNQVGNRIEVSFTLADAVANGNILLTKTFQINANQVRALAHHISDEVYQKLTGERGIFSTRIAYISVQRAGGRSRYSLEVADADGHNPQSLLVSSEPIMSPSWSPNGKSISYVSFEKKKAEIFTVSVETGQRRLITSFPGINGAPAWSPDGQHLAVVLSKSGTPKIYDVDLSSGSMKQLTFGNSIDTEPRYSPDGRSLLFTSGRGGSPQVYRLSLADGQISRVTFEGNYNARASYTPDMKHIVMLHREDRQFNIGVQNTGGGPISNLTFSGLDESPSVSPNSRLVLYATRYQDRGVLGIVSIDGRIRMRLPAREGDVQEPAWSPYLS
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: UNG_STRSV
Sequence: MQHSAWHALIKEQLPEGYFAKINHFLDEVYASGTIYPPREKVFNAIQTTDLADVKVVILGQDPYHGPRQAQGLSFSVPDDIPAPPSLQNILKELADDIGVKESHDLTSWAQQGVLLLNAGLTVPAGQANAHAGLIWESFTDAIIKVVNEKSDPVVFILWGSYARKKKALISNPQHLIIESAHPSPLSAYRGFFGSKPFSRTNDFLVAKGLEPINWLA
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTI_BACHK
Sequence: MLDTLLINIGQLLTMDQEDGLLRREAMNTLPVIENGAVGIENGVITFVGTAEEAKGLQAKEVIDCGGKMVSPGLVDPHTHLVFGGSRENEIALKLQGVPYLEILEQGGGILSTVNATKQASKEELVQKAKFHLDRMLSFGVTTVEAKSGYGLDDETEWKQLEATAQLQKEHPIDLVSTFLGAHAVPKEYKGRSKEFLQWMLDLLPEMKEKQLAEFVDIFCETGVFSVEESKEFLLKAKELGFDVKIHADEIDPLGGAEAAAEIGAASADHLVGASDKGIEMLANSNTVATLLPGTTFYLNKESFARGRKMIDEGVAVALATDFNPGSCPTENIQLIMSIAMLKLKMTPEEVWNAVTVNSSYAINRGDVAGKIRVGRKADLVLWDAYNYAYVPYHYGVSHVNTVWKNGNIAYTRGEQSWSTATI
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_ASPOF
Sequence: MKFNIANPTTGCQKKLEIDDDQKLRAFYDKRISQEVSGDALGEEFKGYVFKIMGGCDKQGFPMKQGVLTPGRVRLLLHRGTPCFRGYGRRNGERRRKSVRGCIVSPDLSVLNLVIVKKGENDLPGLTDVEKPRMRGPKRASKIRKLFNLSKEDDVRKYVNTYRRTFTNKKGKTCSKAPKIQRLVTPLTLQRKRARIAEKKKRVAKAKSEAAEYQKLLASRLKEQRDRRSESLAKKRSRLSAAAAKTASVSA
What is the function of this protein?
Component of the 40S small ribosomal subunit (By similarity).  Plays an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA (By similarity).
What are the official names of this protein?
40S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS6 family.
Protein: APH1A_HUMAN
Sequence: MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVTDRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYVSGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFDACERRRYWALGLVVGSHLLTSGLTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQRSLLCRRQEDSRVMVYSALRIPPED
What is the function of this protein?
Non-catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed:12297508, PubMed:12522139, PubMed:12763021, PubMed:12679784, PubMed:25043039, PubMed:26280335, PubMed:30598546, PubMed:30630874).  Required for normal gamma-secretase assembly (PubMed:12522139, PubMed:12471034, PubMed:12763021, PubMed:19369254).  The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels (Probable).
What are the official names of this protein?
Gamma-secretase subunit APH-1A, APH-1a, Aph-1alpha, Presenilin-stabilization factor.
What is the protein family that this protein belongs to?
Belongs to the APH-1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus, Golgi stack membrane; Multi-pass membrane protein. Note=Predominantly located in the endoplasmic reticulum and in the cis-Golgi.
Protein: COQ4_LEIMA
Sequence: MKNCMMADQRGRSILQYQPIVGDEALEFSRGLAPSTFGFRYAAYMDRNHFLPSGRTAVKHIADPTLAYVMTRYRQCHDFVHIITGCGRSIEEELAVKIFEWKHTGLPLGLLSLLGGAPRLSAAQWAHIRLYWEWASRNAPSSRHGEPAVPMYLNVPWEDMLAKEYDEVVAYTGITPLPDFLEKRQKH
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial, Coenzyme Q biosynthesis protein 4 homolog.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: TAL_SHESW
Sequence: MANTLEQLKSYTTIVADTGDIEAIKRYQPEDATTNPSLILKAAQIPEYSYLIDNAIAWAQTQSTELEQQIDDASDKLAVNIGVEILKLVPGRISTEVDARLSFDKEKSIAKAHKLVRLYQEAGIDKSRILIKLASTWEGICAAKELEQEGINCNLTLLFSFAQARACAEAGVYLISPFVGRILDWYKKDTGKDYAPANDPGVVSVTEIYNYYKQHGYNTVVMGASFRNIGEIIELAGCDRLTIGPSLLEELANSQAQIQAKLLPATTTVAAETPLTEAQFRWDFNQDPMAVEKLAEGIRNFAIDQGKLEVMLKAKLSN
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACT2_SOLTU
Sequence: AGFAGDDAPRAVFPSIVGRPRHAGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIVNNWDDMEKIWHHTFYNELRVAPEERPVLLTEAPLNPKANREKMTQIMFETFNAPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGADLTEYMVKILTERGYSFTTTAEKEIVRDMKEKLAYLALDFEQELETTTTGSAVEKNYELPDGQVITIGAERFRCPEVLYQPSLIGMEAAGIHETTYNSIMKCDVDIRKDLYGNIVLSGGSTMFPGIADRMSKEIQALAPSSMKIKVVAPPERKYSVWIGGSILASLSTFQQ
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.  Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth.
What are the official names of this protein?
Actin-46.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: UVRC_BURP1
Sequence: MTSPDAPESRFEPKPILAQLPHLPGVYRYYDAQDAVLYVGKARDLKKRVSSYFTKTQLSPRIAMMITRIARIETTVTRSEAEALLLENNLIKALAPRYNILFRDDKSYPYLKLTGHRFPRMAYYRGAVDKKNQYFGPFPSAWAVRESIQILQRVFQLRTCEDSVFNNRTRPCLLHQIGRCSAPCVGAIGEEDYARDVDNASRFLLGRQGEVMGELERKMHAFAAELKFEQAAAVRNQMSSLAKVLHQQAIDVGGDSDVDILAVVAQGGRVCVNLAMVRGGRHLGDKAYFPAHVETALALAGDIEALAGEGAGDGVQAAAQPAQAPLATDADATDAAATEAKTVTAAAAARAGARTAQAAGARAAASAEGDVERRAEGETHARADAREAAALPDGAAAAQEADADVDAAPLETEVLEAFIAQHYLGNRVPPVLVVSHAPANRELIDLLVEQAGHKVAVVRQPQGQKRAWLTMAEQNARLALARLLSEQGSQQARTRSLADVLGYESDDLAQLRIECFDISHTMGEATQASCVVYHHHRMQSSEYRRYNIAGITPGDDYAAMRQVLTRRYEKMVEEAAAEASADEAAGIDGNAVHAAASAGRLPNVVLIDGGRGQVEIARQVFSELGLDISMLVGVAKGEGRKVGLETLIFADGRAPLELGKESAALMLVAQIRDEAHRFAITGMRAKRAKTRQTSRLEELEGVGAKRRQRLLARFGGLRGVVAASVDELASVEGISRALAEQIYRQLH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_METPP
Sequence: MKVAASVKKMCRNCKVIRRKGVVRVICTDPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RPIA_METAC
Sequence: MTERNTSTDSPEKRAAGIAAAGLVSSGMLVGLGTGSTVAYTIKELGRRVREEGLDILGVVTSYQSEMLAIEAGIRLTTLAQHPELDLAIDGADQIDSELRAIKGGGAAHTREKIVSVSARRFVVVADESKTSKQLDKLVPVEVLPFAKEPVVKKIRELGGKPQLRSAVKKDGPVITDNGNFVLDVEFGVIKDPEALALQLSSIPGVVEHGIFCNVSELYIGNKDGAIKIITRQK
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: GTA1L_MOUSE
Sequence: MQYKKEALLLMLFAVLLALTQRFSYSRTKDHLQKMYACWKDHLEEPHLSTWFDPKKRPDVIATTGWLAPVLWEGTYNREVLEQYYKRLNITIGLAVFATGNFSKEPLRRFIKSADKYFMVGYNVIFYILADSTYNLPYFELGPLRTLKTWRLFEEEMCQDCNLRNMNNMHSKIIQCIQYEVNFLFMMAVNQTFKNNFGVETLGKSVAQLHAWWYFKKPRDFPYERRTKSAAFIPFEKGDFYYHRAIVGGTPLNVLNLIEQYIKGITDDNTNKLVSTFESHLNKYFFINKPARVLSPEYNWDPRFKTPPEIKHIKIAWKP
What is the function of this protein?
Synthesizes the galactose-alpha(1,3)-galactose group by catalyzing the transfer of a galactose residue, with an alpha-1,3 linkage, on terminal lactosaminide (Gal-beta-1,4-GlcNAc-R) disaccharide borne by a glycoprotein or a glycolipid.
What are the official names of this protein?
N-acetyllactosaminide alpha-1,3-galactosyltransferase-like 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 6 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: DNAJ_OPITP
Sequence: MAKDDYYELLGVQKGASEEELKKAYRKKAVQYHPDKNPGNKEAEEMFKKISHAYEVLKDPEKRAAYDRYGPAAFEGAGAGAGMGGMRGGGGFHDPFDIFREVFGQQGGMGGGIFEEMFGGGRGGGGQDGADLRYDLEITLEEAARGAEKEISFRKLVACERCDGSGAEPGSKRVTCPTCRGAGQVRRSGGIITFTQTCPTCGGMGTKIEKPCTVCHGEGRVRRTTKLNVRIPPGVDNGSRLRSSGNGEAGVAGGQNGDLYIVISVQEHELFERQGDDLFCEIPIKFTLATLGGTIEVPTLFGKASLKIPVGTQSGTTFRLRDKGMPSLRGGRQGDQLVRVHVEVPQSLTPEQRKILEDFARVSGDASEPTSRSFFEKAKKFF
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y474_GEOSW
Sequence: MSGYPAEGEIIQIHSYKHNGLIHRVWEESIVLKGTSTCIIGANDKTMVTEADGRTWVTREPAICFFHAKHWFNIIGMIREEGIYYYCNLSSPFVWDEEALKYIDYDLDIKVFPDMTYILLDEDEYERHRKEMNYPDVIDRILKNNVKKLISWIHERKGPFAPDFIDKWYEKFLSYRK
What are the official names of this protein?
UPF0374 protein GWCH70_0474.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: YOMK_BACSU
Sequence: MFNKKVLKHNLAEMNPKELIKFIKHEFPINGQDYHTHARKVQIIKSLSPSELSSAIARMEGIKSQYDPSKTWGIGSLILGTSFIGFQVLFGVNISKITEGNRLNALIYVLITIIICLWTLRNIIKDKENATTADYLKELLIQIKSEKN
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YomK.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL22_VESOH
Sequence: MKEVKAVHKYAKTSAFKARLVADQIRLKSVEEALNILSFSNKKAAVLVKKVLNSVISNAEHNDGLDIDELFVTSIYIDEGSTMKRIRPRAKGRANRILKRTSHITVGIGK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: EFP_FRACC
Sequence: MATTNDLKNGMTLDIDGVLWNVVGFQHVKPGKGGAFVRTTLKNVLTGKVVDRTFNAGVKVDVATVDRREMTYLYRDGADFVFMDSESYDQIPIPPDVVGGTADYMLENTVATVALHDGAPLYVELPASVELTISQTDPGVQGDRSTGGTKPATLETGATINVPLFITSGEKVKVDTRDGRYLGRVTS
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRPB_AERPE
Sequence: MAFLYREPLERPGLVLRELIEKRDIVVAPGVYNPAVALLAERMGFEALYLSGAAITGSLAMPDLGLITLSELAMFTSYITRVVRVPVIVDADTGFGEAINVERTVRELERAGAAAIQIEDQVMPKKCGHLQGKALISPEDMVKKIIAAVGARRDALIVARTDARGVEGFEKAVERAQLYVEAGADIIFPEALTSLEEFREFARRVKAPLLANMTEFGKTPYITVDQFREAGYKIVIFPVTTFRASLKASETVLREIMEKGTQKDILDKLYTRTEFYDLIGYHDYEKRDAEVSRKAEELLARHNNSRTG
What is the function of this protein?
Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route).  Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.
What are the official names of this protein?
2-methylisocitrate lyase, 2-MIC, MICL, (2R,3S)-2-methylisocitrate lyase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
Protein: WAP_CAMDR
Sequence: LAPALSLPGQAVCPELSSSEDNACIISCVNDESCPQGTKCCARSPCSRSCTVPLMVSSPEPVLKDGRCPWVQTPLTAKHCLEKNDCSRDDQCEGNKKCCFSSCAMRCLDPVTEDSFQ
What is the function of this protein?
Could be a protease inhibitor.
What are the official names of this protein?
Whey acidic protein, WAP.
What are the subcellular locations of this protein?
Secreted.
Protein: PRRP_BOVIN
Sequence: MKAVGAWLLCLLLLGLALQGAASRAHQHSMEIRTPDINPAWYAGRGIRPVGRFGRRRAAPGDGPRPGPRRVPACFRLEGGAEPSRALPGRLTAQLVQE
What is the function of this protein?
Stimulates prolactin (PRL) release and regulates the expression of prolactin through its receptor GPR10.  May stimulate lactotrophs directly to secrete PRL.
What are the official names of this protein?
Prolactin-releasing peptide, PrRP, Prolactin-releasing hormone.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOC_ECODH
Sequence: MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAGEAPAAPQVTAEDASASLAELLNAGLGGSDNE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: PUR9_THEPX
Sequence: MAKKALISVSKKEGIVEFAKKLNELGYEIISTGGTYNLLKENRVNVVKVSDITGFPEIMDGRVKTLHPKIHGGLLAIRDNEEHIKALKEHGIEPIDIVVINLYPFKETILKENVTLEEAIENIDIGGPSMIRAAAKNYKYVTILVDPKDYDTVIEEIKQYGNTKEETRFYLAAKAFGHTALYDSLIYNYLIQKNNIEFPEVMAFAYEKAQDMRYGENPHQKAAFYKNPIKAYGIAECEQLHGKELSFNNINDANAAIELLREFKEPAAVAVKHTNPCGVAIADNIYNAYLKAYESDPVSIFGGIVALNRTVDVKTAEELIKIFLEIVIAPDFEEEAFEILKKKKNLRILRLKEGYEKEYDLKKVEGGLLVQEKDEIDLDENNLKVVTKKAPTQKEMEDLRFAWKVVKHVKSNAIVLAKDGATVGIGVGQVNRIWPTEQAIKQAGSKAKGSVLASDAFFPFPDVVEAAVKGGITAIIQPGGSQNDALSIEAADKGGVSMIFTGIRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: PP1RB_MOUSE
Sequence: MAETGAGISETVTETTVTETTVTETTEPENQSLIMKLRKRKPEKKVEWSSDTVDNEHMGRRSSKCCCIYEKPRAFGESSTESDEDEEEGCSHKHCVRGHRKGRRPTTPAPTPTTPPQPPDPSQPPPGPMQH
What is the function of this protein?
Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome.  Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2 (PubMed:27805901).  Inhibitor of protein phosphatase 1 (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase PPP1R11, Protein phosphatase 1 regulatory subunit 11, T-complex testis expressed protein 5, Tctex-5.