PharMolix/UniProtQA huggingface dataset:
Protein: PTLA_STRMU
Sequence: MNREEATLLGFEIVAYAGDARSKLLEALNAAQAGEYDRAEELVAAADDCIVDAHKAQTSLLAKEAQGDDIELSVTLMHGQDHLMTTILLKDLMKHLIELYKRGS
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II LacEF PTS system is involved in lactose transport.
What are the official names of this protein?
PTS system lactose-specific EIIA component, EIIA-Lac, EIII-Lac, Lactose-specific phosphotransferase enzyme IIA component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOLB_HYDCU
Sequence: MKKVIYTIVGFVFMWSTSVYADLTIQIDQSSDNAVPIALVPFEWKGAQLHPPQNITSIVGNDLLRSGKFKAVDEAKLPSRPKTLDDIDFYQWKQLGVDNLLMGRITEEANGTYQIEMRFVDLLRKEQVIGKRWSGISKSLLRQVAHKMSDLIYEELTGIRGAFNTRMAYVTVRNVKGKKQYSLEVADSDGYNSQPILRSSLPIMSPSWSPDGQHLAYVSFENGRSQIVLQSLDGKSRQIIAKFKGINGAPAWSPDGKKLALTLSKDGSADVYIMDMKTRKLRRLTRNWAIETEAVWAPNGHSLFFNSDRRGQPQIFQVFLDTGEMRRISYVGRYNANPAISPDGRYVAMVHANGGFHIAVLDLYNEDFNILTKTYLDESPTFSPNGEMILYAMNQGGQGKLAVVSVNSNVTQILSVQEGEVRSPSWGPYLPR
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SH3Y1_HUMAN
Sequence: MNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAILSVIKAGFLVTARGGSGIVVARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDRAVEAFAKGGNLTLGGNLTVAVGPLGRNLEGNVALRSSAAVFTYCKSRGLFAGVSLEGSCLIERKETNRKFYCQDIRAYDILFGDTPRPAQAEDLYEILDSFTEKYENEGQRINARKAAREQRKSSAKELPPKPLSRPQQSSAPVQLNSGSQSNRNEYKLYPGLSSYHERVGNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTMN
What are the official names of this protein?
SH3 domain-containing YSC84-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the SH3YL1 family.
Protein: XGPT_VIBVU
Sequence: MSNKFVITWDAMQTYCRQLAEKQMPADQWKGIWAVSRGGLVPGAILARELGIRYVDTICISSYDHDHQRDMTVLKAPEGDGEGYLIVEDLVDSGDTARKLREMYPKAKLIAVCAKPSGKELLDDYVVDIAQDTWIEQPWDMALAYAEPVNRKQK
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PSBJ_LOBMA
Sequence: MADTTGRIPLWVIGTVAGILVIGIIGIFFYGSYSGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: COXX2_PICTO
Sequence: MSMTSQIMKITKLEITILIDIVAIAAFLAVPGSTNHIYDLLILIFAGTLASMSASIFNNIYDMDIDPKMKRTSSRSQILNANTRSLFFIIATAMVLLSFVTSFILLNPVTSAFILGGFASYVLLYTIILKRRTSLNIVIGGIAGSFPALAGWASITGSVSATSLFIAFLVFMWTPTHFWNLSVNNVDDYKKSNIPMLPAVVGIKRTEFWIMVNTSILVIYSILPLFIKEIHVGLLYMPMAAVMDALLIYYVARPMINNYNKKDFKKAFHFSNMYMLMLLIGIMLILVKF
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase 2, Heme B farnesyltransferase 2, Heme O synthase 2.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SSB_PSESM
Sequence: MARGVNKVILVGTCGQDPEVRYLPNGNAVTNLSLATSEQWTDKQSGQKVEKTEWHRVSMFGKVAEIAGEYLRKGSQVYIEGKLQTREWEKDGIKRYTTEIVVDMQGTMQLLGGRPQGDAQQGQGGGGNYNQSAPRPQQSRPQQSAPQQSAPQQNYNQQPPQQRDSRPAPQQQAPQPAADFDSFDDDIPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: CBPB1_PIG
Sequence: MLAFLILVTVTLASAHHSGEHFEGEKVFRVNVEDENDISLLHELASTRQIDFWKPDSVTQIKPHSTVDFRVKAEDILAVEDFLEQNELQYEVLINNLRSVLEAQFDSRVRTTGHSYEKYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKPGPNKPAIFMDCGFHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMWRKTRSTNAGTTCIGTDPNRNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNNLSSIKAYLTIHSYSQMILYPYSYDYKLPENNAELNNLAKAAVKELATLYGTKYTYGPGATTIYPAAGGSDDWAYDQGIKYSFTFELRDKGRYGFILPESQIQATCEETMLAIKYVTNYVLGHL
What are the official names of this protein?
Carboxypeptidase B.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Secreted. Zymogen granule lumen.
Protein: RS24_NATPD
Sequence: MDVDIIDEDENPMLHRTDVRFQLTHEEATPSRLSVRDSLAAKLNKDASEVVVRKLDTKYGMRKTVGHAKVYDSADDAKAVEQDHALERNKIEADEEADEEAAEEA
What are the official names of this protein?
30S ribosomal protein S24e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS24 family.
Protein: NAGK_ECOL5
Sequence: MYYGFDIGGTKIALGVFDSGRQLQWEKRVPTPRDSYDAFLDAVCELVAEADRRFGCKGSVGIGIPGMPETEDGTLYAANVPAASGKPLRADLSARLDRDVRLDNDANCFALSEAWDDEFTQYPLVMGLILGTGVGGGLIFNGKPITGKSYITGEFGHMRLPVDALTMMGLDFPLRRCGCGQHGCIENYLSGRGFAWLYQHYYHQPLQAPEIIALYDQGDEQARAHVERYLDLLAVCLGNILTIVDPDLVVIGGGLSNFPAITTQLAERLPRHLLPVARVPRIERARHGDAGGMRGAAFLHLTD
What is the function of this protein?
Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
What are the official names of this protein?
N-acetyl-D-glucosamine kinase, GlcNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NagK subfamily.
Protein: GCSPB_CHLPM
Sequence: MNEPLISDISRTGRKGYSLNSSDLIRTPHSQLIPGKFLRQSPAELPEVPESEVVRHFLRLSTLNYHVDKDMYPLGSCTMKYNPKINDETCSLEGFAALHPMQPESTVQGALQLMHELSGMLAEITGMASVTLQPAAGAHGELAGILLIKKYHEAQHSKRTTLLVVDSAHGTNPASAALAGYTIVSVKSNGIGRTDLNDLKEKLNGDVAALMLTNPNTIGLFEKEIVAIADMVHKNGSLLYMDGANMNALLGITRPGDMGFDVVHLNLHKTFSAPHGGGGPGSGPVGVCEKLIPHLPVPVIEKRATSEGARYHLTGDCPDSIGRMMNFHGNFAVLIRAYTYIRMLGAEGLRRVSENAIINANYLLSRLDGAYSLPYPKPVLHEFCLSGDLQKKSHGVRTLDIAKRLLDYGFHAPTIYFPLIVSEALMIEPTETESRETLDRFADAMLQIAKEAEECPETVLAAPETTPVRRLDEAMASRQLNICCR
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: VFUS_VACC6
Sequence: MLEFFRPPRARSPRELVQLLPEAWTTSRSSTGSANPSASRKPARYPRIHAPELQSGEARWPLWSRIRPLEDPLKQRLTNLEKKITNVTTKFEQIEKCCKRNDEVLFRLENHAETLRAAMISLAKKIDVQTGRRPYE
What is the function of this protein?
This protein appears to play an important role in virus penetration at the level of cell fusion.  The N-terminal proximal region is essential for fusion ability.  Essential in fusing the outermost of the two Golgi-derived membranes enveloping the virus with the plasma membrane, and in its subsequent release extracellularly.
What are the official names of this protein?
14 kDa fusion protein.
What is the protein family that this protein belongs to?
Belongs to the poxviruses fusion protein family.
What are the subcellular locations of this protein?
Virion membrane. Note=Envelope fraction of virions.
Protein: RECO_CALS8
Sequence: MKFIKAKGIVLKDVNFEESSKILTIFTSELGKIQALSKNCRRTLSPLGAVSQPLIYSEFVFTKTKEIYSISSASVIESFFDITQNVDLTIYSSYLIELVDSFIQIEQKNEDILRLLLNSLYMLKKGADPETVCRIFEIKMLIFTGFFPQFTQCVKCQKSNLSRIFFSFKNAGVVCAECKEENDMEISLEVVEKILIIAATDLKKLSKIRISKNLNNVLKTLMTTYIKLVLQKDVKILDFFKFIK
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: SYE_SALDC
Sequence: MKIKTRFAPSPTGYLHVGGARTALYSWLFARHHGGEFVLRIEDTDLERSTPEAIEAIMDGMNWLNLEWDEGPYFQTKRFERYNAVIDEMLEAGTAYKCYCSKERLEQLREEQMAKGEKPRYDGRCRHSYEHHADDEPCVVRFANPQDGSVIFDDQIRGPIEFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALNAPVPMYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSSGDQEIFTREEMIKLFSLGAVSKSASAFNTDKLLWLNHHYINTLAPEYVATHLQWHIEQENIDTRNGPQLAELVKLLGERCKTLKEMAQSCRYFYEDFSEFDADAAKKHLRPVARQPLEVVRDKLSAITDWSAENVHHAIQATADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGKTRSIERINKALGFIAERESQQ
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_MICRI
Sequence: MTIIRKKHPLIKIINHSFIDLPTPSNISSWWNFGSLLGLCLIMQILTGLFLAMHYTSDTATAFSSVAHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGVYYGSYNMIETWNMGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPTGLNSDSDKIPFHPYFTIKDFLGALILLMAFMILTLFFPDILGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILAIMPLLHTSKQRTLTFRPITQTMYWILVADLFILTWIGGQPVEYPFTIIGQTASIAYFTIIVILMPIAGMIENNILDLD
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CYT_NAJKA
Sequence: MVHFQLPVAAPLCLLCALLLLPSATMIPGGLSPRSVSDPDVQKAAAFAVQEYNARSANAHYYKELRVVEAQSQVVAGEKYYLMMELVKTKCAKTAGKPKVYKEIQNCELPPKAQQEKLTCHFQVWSRPWLDKTELTKMSCN
What is the function of this protein?
Inhibits various C1 cysteine proteases including cathepsin L, papain and cathepsin B.  This protein has no toxic activity and its function in the venom is unknown.  It may play a role as a housekeeping or regulatory protein (By similarity).
What are the official names of this protein?
Cystatin.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: COMB_CLOPE
Sequence: MKIDVIISADYIDSESLKGKIAVVIDMLRATSVITTALYNGAKKVIPVVSVEEAFEKANELKSLGEEVLLGGERKALKIDGFDFSNSPLEYKREIVEGKNVIMSTTNGTRALNLCNKADKVIVASVLNGQAVAKYLENEEKEIVFVNSGTNGEFSSDDFMCAGYIISEICKNKEAELTDIAKTAKYVCESSEGIEEFIKDAKHYNILKNLGLEEDLKYCSTKNLIDLVFEFKNGEIKTVESGVKVTI
What are the official names of this protein?
Probable 2-phosphosulfolactate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the ComB family.
Protein: PDXT_METB6
Sequence: MKVGVLALQGDVSEHIDAFTAALRKRGYTEDSPVIEVRNPEDLAGCAALAIPGGESTTISRLVDKNGLYKPIRDFKGGIFATCAGMILMATDVGDPRVHSLGLLDMTVDRNAFGRQRESFEADIRVQGLDGGSFHAVFIRGPVVTEARDGVVVLARTDKGIVAVEKGRHMALAFHPELGGDLRLHERFLKNLGV
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: RS8_HALLT
Sequence: MTGNDPFTNALAGMDNAESVGHLSYTVEPASNIIGSVLEVLYDRGYVDGFEYVDDGKAGKFEVELKGAINECGAVKPRYSAGADEFEKWEKRYLPARDYGTLIVTTSHGVMSHYEAREEGIGGQVIAYVY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: CITD_LACLA
Sequence: MEIKQHALAGTLESSDVQIMIAPANNGISIDLISDVKKQFGKQIEATVRQVLAAYAIENADVQVIDKGALDLVIKARAIAVVERAIEAKDLNWEVL
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein, Citrate lyase gamma chain.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRA_BRUO2
Sequence: MSFFDSYRKKMQMPSKEEVLPGRVQPIPTAAAHFVSGHPLKGPWPDGMKQVLFGMGCFWGAERLFWQVPGVYVTAVGYAGGITPNPTYEETCTGLTGHAEVVLVVYDPKVVTLNELLALFWEEHDPTQGMRQGNDIGTTYRSVIYTFNAVDRAVAEKSRDAYSQALASRGLGPVTTQIADAPDFYYAEDYHQQYLAKNPDGYCGLRGTGVSCPIPLAH
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: HIS6_CUTAK
Sequence: MAIRVIPCLDVKDGRVVKGVNFVGLRDAGDPVELAAEYGRLGADEVTFLDISASTEGRATTREMVTRCAETVFVPLTVGGGVRGVDDVDVLLRAGADKVGVNTAAIAHPGMIDEVADRFGNQVIVLSVDARREPDRPSGFGVTTHGGTRSAGLDAVEWACQAVERGAGEILLNSMDADGTADGFDIEMIEAVRAAVDVPLIASGGAGKVADFVEAARAGVDAVLAASVFHYHTLTIAQIKDGLRHAGFEVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MODC_RHOPB
Sequence: MRDVSRSIQAQFRGALGRFALDAAFTVPATGITGLFGPSGCGKSTVLRCIAGLQQLPGSTFAIDGDVWQDASQFRQPHQRPIGYVFQEASLFAHLSVKANLLYGAPRDAAHARDSITFDEVIELLGLAALLERSPRHLSGGERQRVAIGRALLSQPKLLLMDEPLSALDRLTKDEILPFLERLHERLALPVIYVSHDMAEIERLADHLVLMRKGQVLAAGPLAALQSDPALPLAASRDAAVNFEATVEDYDPGYGLLTVAVDGGRLLVPAPPAQRGEHRRLRIAAGDVSLARELPHNTSILNVLPARIVSHNPLGDSEILVVLALGGNGEGARLLARVTRRSWDHLELADGIGLIAQVKGVALAPGRNTGTHASSPGLRGR
What is the function of this protein?
Part of the ABC transporter complex ModABC involved in molybdenum import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Molybdenum import ATP-binding protein ModC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NQRED_PSEAE
Sequence: MGVFRTRFTETFGVEHPIMQGGMQWVGRAEMAAAVANAGGLATLSALTQPSPEALAAEIARCRELTDRPFGVNLTLLPTQKPVPYAEYRAAIIEAGIRVVETAGNDPGEHIAEFRRHGVKVIHKCTAVRHALKAERLGVDAVSIDGFECAGHPGEDDIPGLVLLPAAANRLRVPIIASGGFADGRGLVAALALGADAINMGTRFLATRECPIHPAVKAAIRAADERSTDLIMRSLRNTARVARNAISQEVLAIEARGGAGYADIAALVSGQRGRQVYQQGDTDLGIWSAGMVQGLIDDEPACAELLRDIVEQARQLVRQRLEGMLAGV
What is the function of this protein?
Catalyzes the NADH-dependent reduction of a broad spectrum of quinone substrates, generating the corresponding hydroquinones.  Highly prefers NADH to NADPH as a reducing substrate.  Also displays a small NADH oxidase activity.  Does not exhibit nitronate monooxygenase activity; is inactive against propionate 3-nitronate, 3-nitropropionate, nitroethane, 1-nitropropane, 2-nitropropane, and the anionic forms ethylnitronate, propyl-1-nitronate, and propyl-2-nitronate.  Has no azoreductase activity since it is not able to reduce the azo dye methyl red with NADH.  May be required to maintain an appropriate [NAD(+)]/[NADH] ratio for the catabolism of fatty acids in P. aeruginosa PAO1.
What are the official names of this protein?
NADH:quinone reductase.
What is the protein family that this protein belongs to?
Belongs to the nitronate monooxygenase family.
Protein: MHPB_ECO7I
Sequence: MHAYLHCLSHSPLVGYVDPAQEVLDEVNGVIASARERIAAFSPELVVLFAPDHYNGFFYDVMPPFCLGVGATAIGDFGSAAGELPVPVELAEACAHAVMKSGIDLAVSYCMQVDHGFAQPLEFLLGGLDKVPVLPVFINGVATPLPGFQRTRMLGEAIGRFTSTLNKRVLFLGSGGLSHQPPVPELAKADAHMRDRLLGSGKDLPASERELRQQRVISAAEKFVEDQRTLHPLNPIWDNQFMTLLEQGRIQELDAVSNEELSAIAGKSTHEIKTWVAAFAAISAFGNWRSEGRYYRPIPEWIAGFGSLSARTEN
What is the function of this protein?
Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6-ketononatrienedioate, respectively.
What are the official names of this protein?
2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase, 3-carboxyethylcatechol 2,3-dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the LigB/MhpB extradiol dioxygenase family.
Protein: ARY2_MESAU
Sequence: MDIEAYFERIGYQNSRNKLDLQTLTEILQHQIRAIPFENLNIHCGESMELSLETIFDQIVRKKRGGWCLQVNHLLYWALTKMGFETTMLGGYVFNTPANKYSSGMIHLLVQVTISDRNYIVDAGFGRSLQMWEPLELVSGKDHPQVPAIFRLTEENETWYLDQIRREQYVPNQAFVNSDLLEKNKYRKIYSFTLEPRTIEDFESMNTYLQTSPASVFTSKSFCSLQTPEGVHCLVGCTLTYRRFSYKDNVDLVEFKSLKEEEIEDVLKTIFGISLEKKLVPKHGDRFFTI
What is the function of this protein?
Participates in the detoxification of a plethora of hydrazine and arylamine drugs.
What are the official names of this protein?
Arylamine N-acetyltransferase 2, Arylamide acetylase 2, N-acetyltransferase type 2, AT-2, NAT-2, Polymorphic arylamine N-acetyltransferase, PNAT.
What is the protein family that this protein belongs to?
Belongs to the arylamine N-acetyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALBU_CAPHI
Sequence: DTHKSEIAHRFNDLGRHPEYAVSVLLRHLVDEPQNLIKKHGEYGFQNALIVRXXXKAPQVSTPTLVEISRKQTALVELLKLVASTQAALA
What is the function of this protein?
Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs.  Its main function is the regulation of the colloidal osmotic pressure of blood.  Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity).  Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity).  Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (By similarity).  The shared binding site between zinc and calcium suggests a crosstalk between zinc and calcium transport in the blood (By similarity).  The rank order of affinity is zinc > calcium > magnesium (By similarity).  Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E. coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E. coli (By similarity).  Does not prevent iron uptake by the bacterial siderophore aerobactin (By similarity).
What are the official names of this protein?
Albumin.
What is the protein family that this protein belongs to?
Belongs to the ALB/AFP/VDB family.
What are the subcellular locations of this protein?
Secreted.
Protein: PUR7_SALDC
Sequence: MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFDRKGMVNNKFNHFIMTKLAEAGIPTQMERLLSDTECLVKKLEMVPVECVVRNRAAGSLVKRLGVEEGMELNPPIFDLFLKNDALHDPMVNSSYCETFGWVSQENLARMKELTYKANDVLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLDKMDKDRFRQSLGGLIEAYEAVAHRLGVKLD
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: LIPB_HAES1
Sequence: MTDTTLIIRQLGIQDYQQVWQQMREFTDTRNALTPDEIWLVQHPAVFTQGQAGKPEHLLNPTDIPVVQSDRGGQITYHGLGQQIMYVLIDIKRHKANGSELNVRQLVTALEQSVVSTLADYGIKSYPKADAPGVYVNEQKICSLGLRIRKGCSFHGLALNINMDLSPFRQINPCGYIGLEMCQMADFIPTEQAQCDKVAPKLVTHFTQLLGYNDVTTY
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IBPB_ECO8A
Sequence: MRNFDLSPLMRQWIGFDKLANALQNAGESQSFPPYNIEKSDDNHYRITLALAGFRQEDLEIQLEGTRLSVKGTPEQPKEEKKWLHQGLMNQPFSLSFTLAENMEVSGATFVNGLLHIDLIRNEPEPIAAQRIAISERPALNS
What is the function of this protein?
Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpB, 16 kDa heat shock protein B.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.