PharMolix/UniProtQA huggingface dataset:
Protein: CAPSD_BPBMU
Sequence: MGRLSKLRIVDPVLTNLAIGYTNAEFIGQSLMPVVEVEKEGGKIPKFGKESFRLYKTERALRARSNRMNPEDLGSIDIVLDEHDLEYPIDYREDQESAFPLEQAAVQTATEAIQLRREKMVADLAQNPNSYAGGNKKQLSATEKFTAAGSDPVGVIEDGKEAIRTKIGRRPNTMVIGASAYKTLKAHPQLIEKIKYSMKGIVTVDLLKEIFEVENIAVGEAIYADDKDRFTDIWGANIVLAYVPLQRGGQQRTPYEPSYGYTLRKKGNPVVDTRIEDGKLELVRSTDIFRPYLLGADAGYLISGING
What is the function of this protein?
Assembles to form an icosahedral capsid.
What are the official names of this protein?
Major capsid protein, Gene product 34, gp34, Major head protein.
What is the protein family that this protein belongs to?
Belongs to the lambda phage major capsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Forms the capsid icosahedric shell.
Protein: ATPB_STRMU
Sequence: MSTGKIAQVVGPVVDVAFATDDKLPEINNALVVYKDGDKSQRIVLEVALELGDGLVRTIAMESTDGLTRGLEVFDTGRAISVPVGKETLGRVFNVLGDTIDLDKPFAEDAERQPIHKKAPSFDDLSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERRLTQMGIYPAVDPLASSSRALSPEIVGQEHYDVATEVQHVLQRYRELQDIIAILGMDELSDEEKTLVGRARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILEGKYDELPEDAFRSVGAIEDVVEKAKNMGV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL4_ECOHS
Sequence: MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTRAQKTRAEVTGSGKKPWRQKGTGRARSGSIKSPIWRSGGVTFAARPQDHSQKVNKKMYRGALKSILSELVRQDRLIVVEKFSVEAPKTKLLAQKLKDMALEDVLIITGELDENLFLAARNLHKVDVRDATGIDPVSLIAFDKVVMTADAVKQVEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: FABD_ECOL6
Sequence: MTQFAFVFPGQGSQTVGMLADMAASYPIVEETFAEASAALGYDLWALTQQGPAEELNKTWQTQPALLTASVALYRVWQQQGGKAPAMMAGHSLGEYSALVCAGVIDFADAVRLVEMRGKFMQEAVPEGTGAMAAIIGLDDASIAKACEEAAEGQVVSPVNFNSPGQVVIAGHKEAVERAGAACKAAGAKRALPLPVSVPSHCALMKPAADKLAVELAKITFNAPTVPVVNNVDVKCETNGDAIRDALVRQLYNPVQWTKSVEYMAAQGVEHLYEVGPGKVLTGLTKRIVDTLTASALNEPSAMAAALEL
What are the official names of this protein?
Malonyl CoA-acyl carrier protein transacylase, MCT.
What is the protein family that this protein belongs to?
Belongs to the FabD family.
Protein: Y2593_STAAC
Sequence: MRKDAKENRQRIEEIAHKLFDEEGVENISMNRIAKELGIGMGTLYRHFKDKSDLCYYVIQRDLDIFITHFKQIKDDYHSNYEVMQVSLDYLLQFKIDNKALLQCIEAGNNKLRFYQSAFYQELFDFYYDLFKSDDDTYTKFKTDMLLQSLSTSVFAFQIEHRHISIEAYRNYLLNIYLDEVGRND
What are the official names of this protein?
HTH-type transcriptional regulator SACOL2593.
Protein: Y1739_STAHJ
Sequence: MSEVKHLEINYKTDELFEAFREFGNKDLYMVEELQGQMIDASSESPFYGIFHGENLVARMALLKKGDVEEIYFPEFDDYLLLWKLEVLDNYKNKGYGQSLIDYAKSYNMPIKAIARQNSKEFLMNQDFEDVHAKNPEGHDVLVWAPK
What are the official names of this protein?
Uncharacterized N-acetyltransferase SH1739.
Protein: AT2B4_RAT
Sequence: MTNPSGHNLPANSVAESYEGEFGCTLMDLRKLMELRAADAVTQISAHYGSVQEICARLKTSPVEGLSGNPADLEKRRLVFGKNMIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPPGGENEICGHIVSNPEEDEEGETGWIEGAAILASVIIVVFVTAFNDWSKEKQFRGLQSRIELEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKTLDKDPMLLSGTHVMEGSGRMVVTAVGINSQTGIIFTLLGANEEEDDEKKKKGKKQGVSENRNKAKTQDGVALEIQPLNSQEGLDSEEKEKKASKGPKKEKSVLQGKLTRLAVQIGKAGLIMSILTVLILILYFVVDNFVIQRRAWLPECTPVYIQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGGTHYRQIPKPDDLPPNVLDLIVNSICINSAYTSKILPPEKEGGLPRQVGNKTECGLLGFVTDLKQDYQAVRSEMPEEKLFKVYTFNSVRKSMSTVIRKPEGGFRVFSKGASEIMLRKCDRILNKEGGIVPFKTKDRDNMVRNVIEPMASEGLRTIGIAYRDFDGEEPSWENENEIFTGLVCIAVVGIEDPVRPEVPDAINKCKRAGITVRMVTGDNVNTARAIATKCGILTPGDDFLCLEGKEFNRLIRNEKGEVEQEKLDKVWPRLRVLARSSPTDKHTLVKGIIDSNIGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFSGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTDSLLRRRPYGRNKPLISRTMMKNILGHAVYQLGIVFLLVFAGDKLFDIDSGRKAPLNSPPSQHYTIVFNTFVLMQLFNEINSRKIHGEKNVFAGVYRNIIFCSVVLGTFFCQILIVEVGGKPFSCTNLTMEQWMWCLFIGIGELLWGQVISAIPTKSLKFLKEAGHGSDKEEISKDAEGLEEIDHAEMELRRGQILWVRGLNRIQTQIRVVKVFHSFRDVIHKSKNQVSIHSFMTQPEYAADDEMSQSFLNQEESPSLASKSRITKRLSDAETVSQNNTNNNAVDCHQVQIVASHPNSPLQSQETPV
What is the function of this protein?
Calcium/calmodulin-regulated and magnesium-dependent enzyme that catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell (By similarity).  By regulating sperm cell calcium homeostasis, may play a role in sperm motility (By similarity).
What are the official names of this protein?
Plasma membrane calcium-transporting ATPase 4, PMCA4, Plasma membrane calcium ATPase isoform 4, Plasma membrane calcium pump isoform 4.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, cilium, flagellum membrane; Multi-pass membrane protein.
Protein: MET_PLEMO
Sequence: MKAPAVLAPGILVLLFTLVQRSNGECKEALTKSEMNVNMKYQLPNFTAETPIQNVVLHEHHIFLGATNYIYVLNEEDLQKVAEHRTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSDVHCIFSPQIEEPSQCPDCVVSALGTKVLLSVKDRFLNFFVGNTVNSSYFPDHSLHSISVRRLKETKNGFMFLTDQSYVDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLNAQTFHTRIIRFCSINSALHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRSAVCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTFQRNLLGCEARRDEYRTEFTTALQRIDLFAGQFNKVLLTSISTFVKGDLTIANLGTSEGRFIQIVVSRSVPSTPHVNFLLDSHPVSPEVIVEQPLNQDGYTLVVTGKKITKIPLNGLGCRHFQSCSQCLSAPSFVQCGWCHDKCVRSEECSSGTWTQETCLPAIYKVFPTSAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTSSESTMNTLKCTIGPAMNEHFNMSIIISNSHGTTQYSTFSYVDPIITSISPRYGPMSGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEFPVKLKIDLANRETSIFSYLEDPIVYEIHPTKSFISGGSTITGIGKNLNSVSVPRMVINLHEARRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPSDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSISIALLLLLAFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLPDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSQDNADGEVDT
What is the function of this protein?
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand.  Regulates many physiological processes including proliferation, scattering, morphogenesis and survival.  Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules.  Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1.  Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC.  The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects.  During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation.  In adults, participates in wound healing as well as organ regeneration and tissue remodeling.  Promotes also differentiation and proliferation of hematopoietic cells (By similarity).
What are the official names of this protein?
Hepatocyte growth factor receptor, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: TYOBP_RAT
Sequence: MGAPEPSWCFLFLPVLLTVGGLSPVQAQSDNYPGCECSSVSPGVLAGIVLGDLVLTLLIALAVYSLGRLVSRGRGTADGTRKQHMAETESPYQELQGQRPEVYSDLNTQRQYYR
What is the function of this protein?
Adapter protein which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and cell activation following ligand binding by the receptors (By similarity).  TYROBP is tyrosine-phosphorylated in the ITAM domain following ligand binding by the associated receptors which leads to activation of additional tyrosine kinases and subsequent cell activation (By similarity).  Also has an inhibitory role in some cells (By similarity).  Non-covalently associates with activating receptors of the CD300 family to mediate cell activation (By similarity).  Also mediates cell activation through association with activating receptors of the CD200R family (By similarity).  Required for neutrophil activation mediated by integrin (By similarity).  Required for the activation of myeloid cells mediated by the CLEC5A/MDL1 receptor (By similarity).  Associates with natural killer (NK) cell receptors such as the KLRD1/KLRC2 heterodimer to mediate NK cell activation (By similarity).  Associates with TREM1 to mediate activation of neutrophils and monocytes (By similarity).  Associates with TREM2 on monocyte-derived dendritic cells to mediate up-regulation of chemokine receptor CCR7 and dendritic cell maturation and survival (By similarity).  PAssociation with TREM2 mediates cytokine-induced formation of multinucleated giant cells which are formed by the fusion of macrophages (By similarity).  Stabilizes the TREM2 C-terminal fragment (TREM2-CTF) produced by TREM2 ectodomain shedding which suppresses the release of pro-inflammatory cytokines (By similarity).  In microglia, required with TREM2 for phagocytosis of apoptotic neurons (By similarity).  Required with ITGAM/CD11B in microglia to control production of microglial superoxide ions which promote the neuronal apoptosis that occurs during brain development (By similarity).  Promotes pro-inflammatory responses in microglia following nerve injury which accelerates degeneration of injured neurons (By similarity).  ositively regulates the expression of the IRAK3/IRAK-M kinase and IL10 production by liver dendritic cells and inhibits their T cell allosimulatory ability (By similarity).  Negatively regulates B cell proliferation (By similarity).  Required for CSF1-mediated osteoclast cytoskeletal organization (By similarity).  Positively regulates multinucleation during osteoclast development (By similarity).
What are the official names of this protein?
TYRO protein tyrosine kinase-binding protein, DNAX-activation protein 12.
What is the protein family that this protein belongs to?
Belongs to the TYROBP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PURA_SHIDS
Sequence: MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_JANMA
Sequence: MPRRREVPKREILPDPKFGNVDVAKFVNVLMLSGKKSVAENIIYGAFEHIQTKSGKDPLEVFTAAIANCKPLVEVKSRRVGGANYQVPVEVRPVRRMALSMRWLREAANKRSEKSMPQRLAGELLEAAESRGGAMKKRDEVHRMAEANKAFSHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: TBC16_HUMAN
Sequence: MSLGRLLRRASSKASDLLTLTPGGSGSGSPSVLDGEIIYSKNNVCVHPPEGLQGLGEHHPGYLCLYMEKDEMLGATLILAWVPNSRIQRQDEEALRYITPESSPVRKAPRPRGRRTRSSGASHQPSPTELRPTLTPKDEDILVVAQSVPDRMLASPAPEDEEKLAQGLGVDGAQPASQPACSPSGILSTVSPQDVTEEGREPRPEAGEEDGSLELSAEGVSRDSSFDSDSDTFSSPFCLSPISAALAESRGSVFLESDSSPPSSSDAGLRFPDSNGLLQTPRWDEPQRVCALEQICGVFRVDLGHMRSLRLFFSDEACTSGQLVVASRESQYKVFHFHHGGLDKLSDVFQQWKYCTEMQLKDQQVAPDKTCMQFSIRRPKLPSSETHPEESMYKRLGVSAWLNHLNELGQVEEEYKLRKAIFFGGIDVSIRGEVWPFLLRYYSHESTSEEREALRLQKRKEYSEIQQKRLSMTPEEHRAFWRNVQFTVDKDVVRTDRNNQFFRGEDNPNVESMRRILLNYAVYNPAVGYSQGMSDLVAPILAEVLDESDTFWCFVGLMQNTIFVSSPRDEDMEKQLLYLRELLRLTHVRFYQHLVSLGEDGLQMLFCHRWLLLCFKREFPEAEALRIWEACWAHYQTDYFHLFICVAIVAIYGDDVIEQQLATDQMLLHFGNLAMHMNGELVLRKARSLLYQFRLLPRIPCSLHDLCKLCGSGMWDSGSMPAVECTGHHPGSESCPYGGTVEMPSPKSLREGKKGPKTPQDGFGFRR
What is the function of this protein?
May act as a GTPase-activating protein for Rab family protein(s).
What are the official names of this protein?
TBC1 domain family member 16.
Protein: TXF2A_SCOMU
Sequence: MEKKIIFLCFFVSLLTLPEFISSQVLVEDDVPFPEKKFADRGECIRACAAKFTDGDLSKIKDVLPRYYKCVCWYYPTS
What are the official names of this protein?
U-scoloptoxin(15)-Ssm2a, U-SLPTX(15)-Ssm2a, Scolotoxin-Ssm2a.
What is the protein family that this protein belongs to?
Belongs to the SLPTX(15) family.
What are the subcellular locations of this protein?
Secreted.
Protein: HYMA_EMENI
Sequence: MAFFFNRGRSRQPSDVVRSIKDLLLRLREPSTASKVEDELAKQLSQMKLMVQGTQELEASTDQVHALVQAMLHEDLLYELAVALHNLPFEARKDTQTIFSHILRFKPPHGNSPDPPVISYIVHNRPEIIIELCRGYEHSQSAMPCGTILREALKFDVIAAIILYDQSKEGEPAIRLTEVQPNVPQRGTGVFWRFFHWIDRGTFELSADAFTTFREILTRHKSLVTGYLATNFDYFFAQFNTFLVQSESYVTKRQSIKLLGEILLDRANYSVMMRYVESGENLKLCMKLLRDDRKMVQYEGFHVFKVFVANPDKSVAVQRILINNRDRLLRFLPKFLEDRTDDDQFTDEKSFLVRQIELLPKEPIEPSRSAREPSRSTANTTTVA
What is the function of this protein?
Required for conidiophore development.
What are the official names of this protein?
Conidiophore development protein hymA.
What is the protein family that this protein belongs to?
Belongs to the Mo25 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_FRATN
Sequence: MRKILVTNALPYANGDLHLGHMLGYIQSDIWVRFQKLQGNQCIFVCGSDTHGTPIMLKAKSLGITPEELVTKYSNRHLQDFTDFEINFDNYHSTHNSLNKEIVEDIYNKLNNKNLISKKAIAQAYDPEAKMFLPDRFVKGTCPKCKAEDQYGDSCEVCGATYDPTELINPRSVISGQSPIQKNSEHFFFDLPALEKNIKDWIESNTLLQPEVANKLAEWFEQGLQSWDISRDAPYFGFAIPGTNEQKFFYVWLDAPMGYIASFKDYCNRNEIDFDDFWGDNSESELYHFIGKDIIYFHALFWPAILSSTGYKTPTSVFANGFLTVNGKKMSKSRGTFIQARTYLDNLEPSYLRYYFASRLTSRIDDIDLNLEEFVTKSNSDIVGKVVNIASRCAGFIYKKFDATLSGEIFDPELESEFSKNHDAITQAFEKREFAHAVRLIMALADKANQFIDYHKPWQLAKEEGQEQKVHQVCSQGINMFKVLIAYLKPIIPSIVAEAERFLNIQFISWADAPKFLINHKIDKFKPLATRIEKEKVDKILEDTKKMLENEQAPQSKKEEPKLDITAECTFDDFMKVDLRIAKITEASHVEGADKLLKLILDLGGVTKQVFAGIKSAYKPEDLIGKHTVMVANLAPRKMKFGMSEGMVLAAGDGKGIYILEPHEGAQPGMRVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMEB2_HUMAN
Sequence: MATPDVSVHMEEVVVVTTPDTAVDGSGVEGVKTVLVTTNLAPHGGDLTEDNMETENAAAAAAAAFTASSQLKEAVLVKMAEEGENLEAEIVYPITCGDSRANLIWRKFVCPGINVKCVQYDEHVISPKEFVHLAGKSTLKDWKRAIRMNGIMLRKIMDSGELDFYQHDKVCSNTCRSTKIDLSGARVSLSSPTSAEYIPLTPAAADVNGSPATITIETCEDPGDWTAAIGDDTFTFWRGLKDAGLLDEVIQEFHQELVETMRGLQQRVQDPPLQLRDAVLLNNIVQNFGMLDLVKKVLASHKCQMDRSREQYARDLAALEQQCDEHRRRAKELKHKSQHLSNVLMTLTPVSLPPPVKRPRLARATSGPAAMASQVLTQSAQLALGPGVPVPQLTSVPLGKVVSTLPSTVLGKGSLQAPPASSPASPLLGGYTVLASSGSTYPSTVEIHPDASSLTVLSTAAVQDGSTVFKVVSPLQLLTLPGLGPTLQNVAQASPGSSTIVTVPAGAAPGPEEHTATIEVAAMAEDHERK
What is the function of this protein?
Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids.  Binds also to the transferrin receptor promoter.  Essential auxiliary factor for the replication of parvoviruses.
What are the official names of this protein?
Glucocorticoid modulatory element-binding protein 2, GMEB-2, DNA-binding protein p79PIF, Parvovirus initiation factor p79, PIF p79.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=May be also cytoplasmic.
Protein: BCSE_KLEP7
Sequence: MDNVFTLGISSLWDEVCHMPVGGVWWLNVDRYADAVSLFNQTLAAQAKNSHVAALVMGNKPKDIISLDHTHGPDNIALFTLPNRPQALEEIHRDLVCSLEPGNYLFILLCAENAWQNINNEKLCAWVEKTSRWAQYHRCAFLAINSAQDIDRQLTPLLREYRSLSGLASIRYQGDRHIFDIAWWGSDKGISAQQQLMVQHDDAGWRLAQDAETSVQPRSDEKAILSHVRVLEGAPPLSEYWTLFDTNDEVFNAGRTAQAATILFSITQNTQIEQLGRYIHTLRRQRGTALKIIVREQTPSLRATDERLLLSSGASLVIPSSASLSRCLTLIESVQNQKFSRHIPEDFATLLTWSQPLKLRGYQKWDAFCEAVHNVMTNTLLPPDSKGVMVALRPAPGLRVEQALTLCKPNRMGDIMTIGNNRLVLFLSFCRINDLDTALNHIFPLPTGDIFSNRMVWFEDKQILSEIVIMRGVEPARWNTPLPLSVGKNETINATHDGRHWRRYPEPHRLTTREEQA
What is the function of this protein?
Required for cellulose biosynthesis (By similarity).  Binds bis-(3'-5') cyclic diguanylic acid (c-di-GMP) (PubMed:24942809).
What are the official names of this protein?
Cyclic di-GMP binding protein BcsE, Cellulose biosynthesis protein BcsE.
What is the protein family that this protein belongs to?
Belongs to the BcsE family.
Protein: SOAT1_CRIGR
Sequence: MVGEEKMSLRNRLSKSGENPEQDEAQRSVSDTQSNGRITMKQLIAKKRQLAAEAEELKPLFLKEVGCHFDDFVTNLIEKSASLDNGGCALTTFSILEEMKNNHRAKDLRAPPEKGKIFISRRSLLDELFEVDHIRTIYHMFIGLLILFILSTLVVDYIDEGRLVLEFNLLGYAFGKLPTVIWTWWAMFLSTLSIPYFLFQRWAHGYSKTSHPLIYSLSHGFFFLVFQLGILGFVPTYVVLAYTLPPASRFIVILEQIRMVMKAHSFVRENVPRVLNAAKEKSSTVPVPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAVQFLQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLMLFLTFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYAYKDLLWFFSKRFKSAAMLAVFALSAVVHEYALAVCLSYFYPVLFVLFMFFGMAFNFIVNDSRKRPIWNIMVWASLFLGHGVILCFYSQEWYARQHCPLKNPTFLDYVRPRSWTCQYVF
What is the function of this protein?
Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol.  Plays a role in lipoprotein assembly and dietary cholesterol absorption.  Utilizes oleoyl-CoA ((9Z)-octadecenoyl-CoA) preferentially as susbstrate: shows a higher activity towards an acyl-CoA substrate with a double bond at the delta-9 position (9Z) than towards saturated acyl-CoA or an unsaturated acyl-CoA with a double bond at the delta-7 (7Z) or delta-11 (11Z) positions.
What are the official names of this protein?
Sterol O-acyltransferase 1, Acyl-coenzyme A:cholesterol acyltransferase 1, ACAT-1, Cholesterol acyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SHW1_ARATH
Sequence: MAAATTTLSSSSSSPSLTLINASHRFVSVTPFSSNSIFLRRRFRRLNRSLASSSSHSRRRYESDDRFFGGGDNYDVVPDDDGFSDDDDEEDERESSVDLLIRFLRSMFKKVSKRTKKASRRILPAAMSPRLVSFAVDGILLLGSLSITRAFLEVICNLGGTVFTVILLIRLFWAAASFFQTYGNSFGPNPVN
What is the function of this protein?
Negative regulator of photomorphogenesis modulating both light and abscisic acid (ABA) signaling pathways (PubMed:19704523, PubMed:18375596, PubMed:26474641).  Regulates negatively the light-mediated inhibition of hypocotyl elongation, probably in a PHYB-mediated signaling pathway, but promotes flowering time (especially in long days) and lateral root formation (PubMed:18375596, PubMed:19704523).  Enhances light-regulated gene expression (PubMed:18375596).  Promotes COP1-mediated degradation of HY5 during seedling development (e. g.  hypocotyl growth) through enhanced ubiquitination in the darkness.  Also involved in root gravitropism (PubMed:26474641, PubMed:18375596).
What are the official names of this protein?
Protein SHORT HYPOCOTYL IN WHITE LIGHT 1.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein. Note=Constitutively localized in the nucleus of hypocotyl cells.
Protein: FABZ_SODGM
Sequence: MTTDTHTLHIEEILELLPHRFPFLLVDRVLDFEKGKFLRAVKNVSFNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKSAGKLAPGELYYFAAIDEARFKRPVQPGDQMILEVEFIKERRGVARFKGVAKVDGEVACEASMMCARRREA
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_ACIAC
Sequence: MATFKKFNKDKRPKRNTQSLLFKRKRFCRFTVAGVEEIDYKDVDTLRDFIAENGKIIPARLTGTRAIYQRQLNTAIKRARFLALVPYSDQHKI
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: CINA_BACVZ
Sequence: MEIAKKAEIIAVGSELLLGQIANTNAQFISKELAEIGVNVFYHTAVGDNPERLKQVIRIAEERSDLIIFSGGLGPTKDDLTKETIANTLGRPLVLNDEAFRSIEEYFAKTKRTMSPNNRKQALVIEGSDVLANHFGMAPGMLAEHGSRLYMLLPGPPSELRPMFENEAKPLLLKKLGSNEKIVSTVLRFFGIGESQLEADLEDIIDAQTNPTIAPLAADGEVTLRLTAKHADEKETERLLKETEAAILERVGEFFYGYDDTSLVKELSKACRQNGITISSAESFTGGLFSEWVTDLSGASQLFAGGVVCYSDSVKQHVLGVKAETLAESGAVSKECAKELAAGVRKLTGSDIGISFTGVAGPDPQEGHAPGRVFIGISAEGKEEVHEFNFAGSRTGIRKRAAKYGCHLILKMLDQK
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: MAND_ESCAT
Sequence: MKIVRAEVFVTCPGRNFVTLKITTEDGITGLGDATLNGRELSVASYLQDHLCPQLIGRDAHRIEDIWQFFYKGAYWRRGPVTMSAISAVDMALWDIKAKVANMPLYQLLGGASREGVMVYCHTTGHSIEEALDDYARHQELGFKAIRVQCGIPGMKTTYGMSKGKGLAYEPATKGQWPEEQLWSTEKYLDFMPKLFDAVRNKFGFDEHLLHDMHHRLTPIEAARFGKSIEDYRMFWMEDPTPAENQECFRLIRQHTVTPIAVGEVFNSIWDCKQLIEEQLIDYIRTTLTHAGGITGMRRIADFASLYQVRTGSHGPSDLSPVCMAAALHFDLWVPNFGVQEYMGYSEQMLEVFPHNWTFDNGYMHPGDKPGLGIEFDEKLAAKYPYEPAYLPVARLEDGTLWNW
What is the function of this protein?
Has low D-mannonate dehydratase activity (in vitro), suggesting that this is not a physiological substrate and that it has no significant role in D-mannonate degradation in vivo.  Has no detectable activity with a panel of 70 other acid sugars (in vitro).
What are the official names of this protein?
D-galactonate dehydratase family member RspA, D-mannonate dehydratase, Starvation sensing protein RspA homolog.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.