PharMolix/UniProtQA huggingface dataset:
Protein: VIF_SIVM1
Sequence: MEEEKRWIVVPTWRIPERLERWHSLIKYLKYKTKDLQKACYVPHHKVGWAWWTCSRVIFPLQEGSHLEVQGYWNLTPERGWLSTYAVRITWYSKDFWTDVTPEYADILLHSTYFPCFTAGEVRRAIRGERLLSCCRFPRAHKHQVPSLQYLALRVVSHVRSQGENPTWKQWRRDNRRSLRVAKQNSRGDKQRGGKPPTEGANFPGLAKVLGILA
What is the function of this protein?
Counteracts the innate antiviral activity of APOBEC3G.  Forms a complex with host APOBEC3G thus preventing the entry of this lethally hypermutating enzyme into progeny virions.  Functions as an adapter molecule, recruiting APOBEC3G to the ubiquitin-proteasome machinery.  Targets APOBEC3G for degradation through the assembly with elongin BC complex, CUL5 and RBX1.  Binds viral RNA and affects the stability of viral nucleoprotein core.  May play a role in viral morphology (By similarity).
What are the official names of this protein?
Virion infectivity factor, Vif, Q protein, SOR protein.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group Vif protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Virion. Note=Seems to colocalize with intermediate filament vimentin. A fraction is associated with the cytoplasmic side of cellular membranes, presumably via the interaction with Pr55Gag precursor (By similarity).
Protein: RL4_AGRFC
Sequence: MELNVKTLEGKDAGKVSLSDEIFGLDPRQDILARMVRWQLAKKQQGTHKTKNRSEVSRTGAKMYKQKGTGRARHHSARAPQFRGGGKAHGPVVRSHAHDLPKKVRALALRHALSAKLKAEELIIVDQLVASEAKTKALLGSFASLGLTNALVIGGAELDGNFKLAAQNIPNVDVLPVQGINVYDILRRGKLVLSKAAVEALEERFK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: KCNB2_CANLF
Sequence: MAEKAPPGLNRKTSRSTLSLPPEPVDIIRSKTCSRRVKINVGGLNHEVLWRTPDRLPRTRLGKLRDCNTHESLLEVCDDYNLGHNEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSVGQELDYWGIDEIYLESCCQARYHQKKEQMNEELRREAETMRDGEGEEFDNTCCPEKRKKSRDLLEKPNSSVAAKILAIVSNLFIVLSTIALSLNTLPELQEMDEFGQPNDNPQLAHVEAVCNAWFTMEYLLRFLSSPNKWKFFKGPLNVIDLLAILPYYVTIFLTESNKSVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDADATKFTSIPASFWWATITMTTVGYGDIYPKTLLGKSVGGLCCIAGVLVIALPIPIIVPPFSEFYKEQKRQEKAIKRREALERAKRNGSIVSMNLKDAFARSMELIDVAVEKAGESSSTKDSADDNHLSPSRWKWARKALSETSSNKSYENKYQEVSQKDSHEQLNNTSSSSPQHLSAQKLEMLYNEITKTQPHPAPNPDGQEQPDRPSAYEEEIEMEEVVCPQEQLAVAQGEVIVDMKSTSSIDSFTSCATDFTETERSPLPPLSASHLQMRFPPDLAGTDEHQRARGPPFLMLARGKGPAGRDAILEYAPVDITVSLDASGSKVGSHGPLQPDSASESPKSSLKGSNPLKSRSLRVNFKENRGSAPQTPPSTARPLPVTTADFSLTAPQLISTILLEETPSQGDRPLLGAEGSAHCQGPSKGLSPRFPKQKLFPFSSRERRSFTEIDT
What is the function of this protein?
Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and smooth muscle cells (PubMed:9612272).  Channels open or close in response to the voltage difference across the membrane, letting potassium ions pass in accordance with their electrochemical gradient.  Homotetrameric channels mediate a delayed-rectifier voltage-dependent outward potassium current that display rapid activation and slow inactivation in response to membrane depolarization (PubMed:9612272).  Can form functional homotetrameric and heterotetrameric channels that contain variable proportions of KCNB1; channel properties depend on the type of alpha subunits that are part of the channel.  Can also form functional heterotetrameric channels with other alpha subunits that are non-conducting when expressed alone, such as KCNS1 and KCNS2, creating a functionally diverse range of channel complexes.  In vivo, membranes probably contain a mixture of heteromeric potassium channel complexes, making it difficult to assign currents observed in intact tissues to any particular potassium channel family member.  Contributes to the delayed-rectifier voltage-gated potassium current in cortical pyramidal neurons and smooth muscle cells (By similarity).
What are the official names of this protein?
Potassium voltage-gated channel subfamily B member 2, Voltage-gated potassium channel subunit Kv2.2.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.2/KCNB2 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Perikaryon. Cell projection, dendrite. Note=Localized uniformly throughout cell bodies and dendrites. Colocalizes with KCNB1 to high-density somatodendritic clusters on cortical pyramidal neurons.
Protein: RPOA_AGRCR
Sequence: MVREEVAGSTQTLQWKCVESRVDSKRLYYGRFILSPLRKGQADTVGIALRRALLGEIEGTCITRAKFGSVPHEYSTIAGIEESVQEILLNLKEIVLRSNLYGVRDASICVKGPRYITAQDIILPPSVEIVDRAQPIANLTEPIDFCIDLQIKRDRGYQTELRKNYQDGSYPIDAVSMPVRNVNYSIFSCGNGNEKHEILFLEIWTNGSLTPKEALYEASRNLIDLFLPFLHAEEEGTSFEENKNRFTPPLFTFQKRLTNLKKNKKGIPLNCIFIDQLELTSRTYNCLKRANIHTLLDLLSKTEEDLLRIDSFRMEDRKHIWDTLEKHLPIDLLKNKLSF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PGM_ARATH
Sequence: MDNEGIGLYPLHRCKTIHLVRHAQGIHNVAGEKDHSAYSSEDYFDAHLTPLGWQQVDNLRNHVRAAQLLNKVELVIVSPMLRTIQTAVGAFGGEEDTNGADATPLMVANAGSSDRPAISSLNSPPFLAVELCRETMGDHPCDRRRSVTEYKALFPAIDFSIIETDNDVLWKPSPRESLEEVAARGVEFIKWIWTRKEKEIAIVSHSGFLHGLLSSFGKDCCDDLKKELSIHLSNCELRSMVIVDRGNLGTDSAETTNYPGKVPEGLDNPSG
What is the function of this protein?
May play a role in carbohydrates metabolism.
What are the official names of this protein?
Phosphoglycerate mutase-like protein, AtPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family.
Protein: UP24_BOMMO
Sequence: GPEVTFLKXM
What are the official names of this protein?
Unknown protein 24 from 2D-PAGE.
Protein: FA98A_MOUSE
Sequence: MECDLMETDILESLEDLGYKGPLLDDGALLQAVSAGAASPEFTKLCAWLVSELRVLCKLEENVQATNSPSEAEEFQLEVSGLLGEMNCPYPSLTSGDVTKRLLVEKNCLLLLTYLISELEAARMLCVNAPPKKAQEGGGSEVFQELKGICIALGMSKPPANITMFQFFSGIEKKLKETLAKVPPNHVGKPLLKKPMGPAHWEKIEAINQAIANEYEVRRKLLIKRLDVTVQSFGWSDRAKSQTDKLAKVYQPKRSLLSPKGKVSVAHLLAARQDLSKILRTSSGSIREKTACAINKVLMGRVPDRGGRPNEIEPPPPEMPPWQKRQDGPQQQAGGRGGGRGGYEHSSYGGRGGHEQGGRGGRGSYDHGGRGGGRGNKHQGGWTDGGSGSGGGYQDGAYRDSGFQPGGYHGGHSGGYQAGGYGGFQTSSYTGSGYQGGGYQQDNRYQDGGHHGERGSGRGGRGGRGGRGGRGSQGGGWGGRGSQTYHQGGQFEQHFQHGGYQYSHSGFGQGRHYTS
What is the function of this protein?
Positively stimulates PRMT1-induced protein arginine methylation (By similarity).  Involved in skeletal homeostasis (PubMed:27777970).  Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts (PubMed:27777970).
What are the official names of this protein?
Protein FAM98A.
What is the protein family that this protein belongs to?
Belongs to the FAM98 family.
Protein: RECA_YERP3
Sequence: MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPIYAKKLGVDIDNLLCSQPDTGEQALEICDALTRSGAVDVIIVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKNANTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKDGDVVVGSETRVKVVKNKIAAPFKQAEFQILYGEGININGELVDLGVKHKLIEKAGAWYSYNGDKIGQGKANASNYLKENPAIAAELDKKLREMLLNGGNGEQPVAAATAEFADGVDETNEEF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GDL27_ARATH
Sequence: MKIQILLFALVLIFVEANAATQGKNTTIPALIVFGDSIMDTGNNNNLPTLLKCNFPPYGKDYPGGFATGRFSDGRVPSDLIAEKLGLAKTLPAYMNPYLKPEDLLKGVTFASGGTGYDPLTAKIMSVISVWDQLINFKEYISKIKRHFGEEKAKDILEHSFFLVVSSSNDLAHTYLAQTHRYDRTSYANFLADSAVHFVRELHKLGARKIGVFSAVPVGCVPLQRTVFGGFFTRGCNQPLNNMAKQFNARLSPALDSLDKELDGVILYINVYDTLFDMIQHPKKYGFEVADRGCCGKGLLAISYLCNSLNPFTCSNSSAYIFWDSYHPSERAYQVIVDNLLDKYLSKVY
What are the official names of this protein?
GDSL esterase/lipase At1g59406, Extracellular lipase At1g59406.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: MTGA_ACIBT
Sequence: MKAFIVRVLLIFIGAILFIQLWIFSSLVWWRTHEVDTTMFMRIDYWSDTSEPIIHEWLDYDDISDNFKHAILAGEDAKFIHHHGFDWDGIRFALERNNEQGEVVAGGSTVSQQLAKNLFLYNKRSFIRKGQETVATWMMERMWSKRRILEVYMNSVEFGKNLYGVEAAAQYYYGKSAKNLTREQAAFLAALLPDPKYYQDHRNDRKLQYRKRVILRYMNSTQIPE
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: YBFA_ECO57
Sequence: MELYREYPAWLIFLRRTYAVAAGVLALPFMLFWKDRARFYSYLHRVWSKTSDKPVWMDQAEKATGDFY
What are the official names of this protein?
Uncharacterized protein YbfA.
Protein: DGTL1_BRUSU
Sequence: MSLEGIGFGYRERAPYASNPAFSRGRLVPEPESPTRTPFQRDRDRIIHSTAFRRLKHKTQVFIAHEGDHYRTRLTHTIEVAQIARALARALRLDEDLAEAVALVHDFGHTPFGHTGEDALNERMKNFGGFDHNAQSLRIVTKLEHRYADFDGLNLSWETLEGLVKHNGPLLGPYAAHPDIPVPQPILDFNARYDLELSRFASLEAQCAAIADDIAYNAHDIDDGLRAGLLTLESLDEVPLAKRLLDIVRTRYPNLDPVRTGHELVRRQITIMVEDVIEEAQRRLASARPGTMEDVHNQPRALVGFSDAMRAEEKVLKRFLFKNLYFHESVVVRRHAADRIVQDLFDACFTDPSLMPDEWRLGCEALDKAALARRVADYLAGMTDNYAVREHRRLFDRTPDLA
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: RL15_ECOHS
Sequence: MRLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKGQKSRSGGGVRRGFEGGQMPLYRRLPKFGFTSRKAAITAEIRLSDLAKVEGGVVDLNTLKAANIIGIQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIEAAGGKIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RPOA_CRIDE
Sequence: MVREEVAGSTQTLQWKCVESRVDSKRLYYGRFILSPLRKGQADTVGIALRRALLGEIEGTCITRAKFGSVPHEYSTIAGIEESVQEILLNLKEIVLRSNLYGVRDASICVKGPRYITAQDIILPPSVEIVDTAQPIANLTEPIDFCIDLQIKRDRGYQTELRKNYQDGSYPIDAVSMPVRNVNYSIFSCGNGNEKHEILFLEIWTNGSLTPKEALYEASRNLIDLFLPFLHAEEEGASFEENKNRFTPPLFTFQKRLTNLKKNKKGIPLNCIFIDQLELTSRTYNCXKRXXXXTLLDLLSKTEEDLLRIDSFRMEDRKHIWDTLEKHLPIDLLKNKLSF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FLAA_VIBC3
Sequence: MTINVNTNVSAMTAQRYLTKATGELNTSMERLSSGNRINSAKDDAAGLQISNRLTAQSRGLDVAMRNANDGISIAQTAEGAMNESTSILQRMRDLALQSANGTNSASERQALNEESVALQDELNRIAETTSFGGRKLLNGSFGEASFQIGSSSGEAIIMGLTSVRADDFRMGGQSFIAEQPKTKEWGVPPTARDLKFEFTKKDGEAVVLDIIAKDGDDIEELATYINGQTDLFKASVDQEGKLQIFVAEPNIEGNFNISGGLATELGLNGGPGVKTTVQDIDITSVGGSQNAVGIIDAALKYVDSQRADLGAKQNRLSHSISNLSNIQENVEASKSRIKDTDFAKETTQLTKSQILQQAGTSILAQAKQLPNSAISLLQ
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.  FlaA is required to form a core or scaffold into which the other flagellins are inserted to provide structural integrity.  Essential for flagellar synthesis and motility; important for full virulence.
What are the official names of this protein?
Flagellin A, Flagellin core protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: RL29_AGRRK
Sequence: MKAADVRALSADQLKDELAKLKKEQFNLRFQKATGQLEKSSRINEVRKDIARVKTIARQKAAEAKA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: ARND_SALPK
Sequence: MTKVGLRIDVDTLRGTREGVPRLLATLHRHGVQASFFFSVGPDNMGRHLWRLIKPRFLWKMLRSNAASLYGWDILLAGTAWPGKNIGNANAGIIRETATYHETGLHAWDHHAWQTHSGHWSIRQLEEDIARGITALEAIIGKPVTCSAAAGWRADGRVVRAKEPFNLRYNSDCRGTTLFRPLLMPGQTGTPQIPVTLPTWDEVIGPAVQAQSFNTWIISRMLQDKGTPVYTIHAEVEGIVHQPLFEDLLVRARDAGITFCPLGELLPASPESLPLGQIVRGHIPGREGWLGCQQAVSAS
What is the function of this protein?
Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
Protein: SECA2_CORGB
Sequence: MAGFDWFWKALGGKSGRNQKRSVAIVNQAENHVAELDALDDVALAQRAKDLASGGRIDNHAEFLAILGVASQRTLGLKPYPAQSQAVLRLIEGDVVHMATGEGKTLVGAMAATGLGLMGKRVHSITVNDYLAVRDAEWMRPLVEFFGLSVASISEKMDAGERRQAYKAAIVYGPVNEIGFDVLRDQLITRREDAVQHGADVAIIDEADSVLVDEALVPLVLAGNQPGHAPRGKITDVVRSLKENDDYTIDDDRRNVFLTDKGAAKLEQQLGISSLYDDEHVGSTLVQVNLALHAQALLIRDIHYIVRDSKVLLIDASRGRVADLQRWPDGLQAAVEAKEGLAVSEGGKILDTITLQALIGRYPMACGMTGTAVEATNQLRTFYDLHVSVIERNHPLKRFDEADRIYATMAEKNRAIIDEIALLHSTGQPVLVGTHDVAESEELATALRELNIEVSVLNAKNDAEEAQIIAEAGDIGRVTVSTQMAGRGTDIRLGGADEADYDEVVKLGGLAVIGTARHRSQRLDNQLRGRAGRQGDPGLSLFFVSLDDDVVVSGGSGESVSAQPDATGLIDSDRIRDWVGHCQRVTEGQLLEIHSQSWNYNKLLADQRVIIDERRERLLDTALAWEELAQHAPARAAELEDLDQSVREQAGRDIMLYHLDYNWSEHLALMDDVRESIHLRAIARETPLDEYHRIAVREFKDLAQRAVDDAVSTFKSVTIDHEGAHLDDEGLARPSATWTYMVSDNPLAGSGNSVISGIGNIFR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 2.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: TNAA1_SYMTH
Sequence: MPKGEPFKIKMVEPIRLIPREDRERALKEAHYNPFFLRSSDVYIDLLTDSGTGAMSQFQWSAMMLGDESYAGASSYYRLKETVTDITGYEYVIPTHQGRGAEKVAFSQLITRPGMYVLSNMFFDTTRGHVQLAGGRPVDLLIDVPTEEYHPFKGNMDTERLEQFIREHGAENIACIVMTVTNNSAGGQPVSMANIRETYQIARKYGVLVLFDVARYAENCHFIRMREEGYADKHPIDIAREMFSYGDGLMMSAKKDALVNIGGLLAFRDEELFTKVGAAVVPFEGFLTYGGLAGRDLEAMAVGLREALDPDYLAYRVGQVQYLGEMLRNAGIPIQWPVGGHAVFIDAAKFLPHVPWDQFPGHALTLALYLEGGVRTVEVGSLMIGRDPETGENVRGPFEFTRLAIPRRVYTNLHLEDVAETVINAFQKREEIRGVKFAREPKVLRHFTAWFDPA
What are the official names of this protein?
Tryptophanase 1, L-tryptophan indole-lyase 1, TNase 1.
What is the protein family that this protein belongs to?
Belongs to the beta-eliminating lyase family.
Protein: RAD50_ARATH
Sequence: MSTVDKMLIKGIRSFDPENKNVVTFFRPLTLIVGANGAGKTTIIECLKVSCTGELPPNARSGHSFIHDPKVAGETETKAQIKLRFKTAAGKDVVCIRSFQLTQKASKMEYKAIESVLQTINPHTGEKVCLSYRCADMDREIPALMGVSKAILENVIFVHQDESNWPLQDPSTLKKKFDDIFSATRYTKALEVIKKLHKDQAQEIKTFKLKLENLQTLKDAAYKLRESIAQDQERTESSKVQMLELETSVQKVDAEVHNKEMMLKDLRKLQDQVSIKTAERSTLFKEQQRQYAALPEENEDTIEELKEWKSKFEERLALLGTKIRKMEREMVDTETTISSLHNAKTNYMLEISKLQTEAEAHMLLKNERDSTIQNIFFHYNLGNVPSTPFSTEVVLNLTNRIKSRLGELEMDLLDKKKSNETALSTAWDCYMDANDRWKSIEAQKRAKDEIKMGISKRIEEKEIERDSFEFEISTVDVKQTDEREKQVQVELERKTKQNSERGFESKIEQKQHEIYSLEHKIKTLNRERDVMAGDAEDRVKLSLKKTEQENLKKKHKKIIDECKDRIRGVLKGRLPPEKDMKREIVQALRSIEREYDDLSLKSREAEKEVNMLQMKIQEVNNSLFKHNKDTESRKRYIESKLQALKQESVTIDAYPKLLESAKDKRDDRKREYNMANGMRQMFEPFEKRARQEHSCPCCERSFTADEEASFIKKQRVKASSTGEHLKALAVESSNADSVFQQLDKLRAVFEEYSKLTTEIIPLAEKTLQEHTEELGQKSEALDDVLGISAQIKADKDSIEALVQPLENADRIFQEIVSYQKQIEDLEYKLDFRGLGVKTMEEIQSELSSLQSSKDKLHGELEKLRDDQIYMERDISCLQARWHAVREEKAKAANLLRDVTKAEEDLERLAEEKSQLDLDVKYLTEALGPLSKEKEQLLSDYNDMKIRRNQEYEELAEKKRNYQQEVEALLKASYKINEYHDLKKGERLDDIQEKQRLSDSQLQSCEARKNELAGELNRNKDLMRNQDQLRRNIEDNLNYRTTKAKVEELTREIESLEEQILNIGGIAAVEAEIVKILRERERLLSELNRCRGTVSVYESSISKNRVELKQAQYKDIDKRHFDQLIQLKTTEMANKDLDRYYNALDKALMRFHTMKMEEINKIIRELWQQTYRGQDMDYIRIHSDSEGAGTRSYSYKVLMQTGDTELEMRGRCSAGQKVLASLIIRLALAETFCLNCGILALDEPTTNLDGPNSESLAGALLRIMEDRKGQENFQLIVITHDERFAQMIGQRQHAEKYYRVAKDDMQHSIIEAQEIFD
What is the function of this protein?
Implicated in double-strand breaks (DSBs) repair by non-homologous end joining (NHEJ).  Involved in telomere maintenance.  Involved in telomerase action on chromosome ends.  Required during meiosis for both male and female gametophytic development, for pairing and synapsis of homologous chromosomes during the early stages of meiotic recombination, especially during the pachytene stage of the first division.
What are the official names of this protein?
DNA repair protein RAD50, AtRAD50.
What is the protein family that this protein belongs to?
Belongs to the SMC family. RAD50 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: COX1_EPHMA
Sequence: GAITMLLTDRNFNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGIISQIVSTLSGKQVFGYLGMVYAMISIGVLGFMVWAHHMFTVGLDVDTRAYFTAATMIIAVPTGIKIFSWIATMWGGSIRSITPMLFAVGFLFLFTIGGLTGIVLANSGLDIALHDTYYVVAH
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
Protein: RL31B_BACSU
Sequence: MKEGIHPKNHKVIFQDVNSGYRFLSTSTKTSNETAEWEDGNTYPVIKVEVSSDTHPFYTGRQKFNEKGGRVEQFKKRYNMGK
What is the function of this protein?
While neither of the L31 paralogs is essential, this protein does not seem to function as the main L31 protein.  Has a higher affinity for 70S ribosomes than the zinc-containing L31 paralog; is able to displace it to varying extents, even under zinc-replete conditions.
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: GCST_THISH
Sequence: MSKQTPLYEKHLEAGARMVDFGGWSMPLHYGSQIEEHHAVRRDAGMFDVSHMTVVDVQGNGARDYLRFLLANDVAKLKVPGKALYSCMLTPEGGVVDDLITYYLSDTFYRLVVNAATRDKDLAWMRDRATGFDVLLQERDDLAMVAVQGPHGRDKALSVLDGEIARVADALSPFVGGQAGDWFVGRTGYTGEDGFEIMLPAAEAPAFWDRLKVAGVQPAGLGARDTLRLEAGMNLYGQDMDEQVSPLESGLAWTVAFEPAERDFVGRAALEKQKAAGGLRRFVGLVLEGRGVLRGHMRVLCGAAGEGEITSGGFSPTLGVSIALARVPAGTGERVEVDVRGKPQPARLVKPPFVRNGQACVEI
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: AMY3D_ORYSJ
Sequence: MKNTSSLCLLLLVVLCSLTCNSGQAQVLFQGFNWESWKQQGGWYNMLKGQVDDIAKAGVTHVWLPPPSHSVAPQGYMPGRLYDLDASKYGTAAELKSLIAAFHGKGVQCVADVVINHRCAEKKDARGVYCVFEGGTPDDRLDWGPGMICSDDTQYSDGTGHRDTGEGFGAAPDIDHLNPRVQRELTDWLNWLKSDVGFDGWRLDFAKGYSTDIAKMYVESCKPGFVVAEIWNSLSYNGDGKPAANQDQGRQELVNWVNAVGGPAMTFDFTTKGLLQAGVQGELWRLRDGNGKAAGMIGWLPEKAVTFVDNHDTGSTQKLWPFPSDKVMQGYAYILTHPGVPCIFYDHMFDWNLKQEITALAAIRERNGINAGSKLRIVVADADAYVAVVDEKVMVKIGTRYDVGNAVPSDFHQTVHGKDYSVWEKGSLRVPAGRHL
What is the function of this protein?
Important for breakdown of endosperm starch during germination.
What are the official names of this protein?
Alpha-amylase isozyme 3D, 1,4-alpha-D-glucan glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: Y338_MYCGE
Sequence: MAHRFKRWSLIALAFSGVGATAIITACSTINTANLFPTLNRSQKLIGFSDQNIINPDVVLKSALNDGSGVDSILRVSFGSALQKWYQANADRNISNRLKIFEENVEDEHDNLIDEKKRADRVKWPIEVQKEYDQFGGNQESWKKLKLYDRLITDFQSLIFNNISANVSLVNSSDTSVATTKENIEKTENKLKFINSNLNDVNGDFFTNLQAYLFSQWLIEENPFLLNQASFNYQSPIAGLGSIYDENAIGASNLNLSYNFPAFQDPSESGGQTNSAKLFEEFDKQLQTANSSGSSQSSAATNTRNDLLDFENKYSASKVLISKNNILSVLKTVNLSAAVIDQYHYLLNNKTELTTTTTTTTTTGGTSSNLNPLDKFIKSSSATTVMMKSAMTKSQEVTSDNNGFNVKSEFLKINPSLSSSGSDNSSNTQSFWKQVQALNNSSQTATIFDAVRMESNSSQAQVVTSNLLVSLSSKTTQKQQQKPVYVRGDDAIYAFHIDGGNYFLENSSPNKRNFEKQAEVLLMRFLQGQTNNFSKDNVSFSVDLFGSNSEFRSWANRNTTLKLYTALTTMLENGTSNNNGQKDVCDLAKKLLKNNTNLSETIKKQQDFNNSLSQIKSSYESYIKAANKLNNFRTDLANIEKLEQAIVDRANNYIKLQKEAKESSIGWGQPLPYKRANDGSYPSLAKFFNNNSDQSSAQTLTLKTTAAAITSDNEPTREKNNQTLKTLTTEVENKAKELVEKWKATTYSSSQYSEIITLKSSQLNDLDLDLILSLLTDSGIRTGTVANIFKNWYFKNTNSFTNNFDTSNKELKGEFSDFNDLVKQALYIRSWQNLTSKERFGYYKDLGSVNSTSTMLQMQNKAAQSHTSSSVNQTLLDLAKKAFEKELEDPNQDAEYKYMRFLQALMWLVKNGAQNYKNLLQQAIPIGTRAFVSWTVGYDKNPSATVSQKTKSSTSSANENPFNRFLQNPNYTQGSEINWFNDKQTPIQPDSLLESENTYRFTDEPFNNSVALSNKSQGSSDKKYFYGFNGLTINSNQSISTASAGLTQQLFNNYGQLITATDKAGALSQYKDKFTLWSLINKTSSDAELNAFGELLHRSVNVDTNNLSRFNSRGEPLISFDNKKKFLLNVVDRLDDLYFHKFEGYVGLSKAANTDGSNTEGYKTVQTVPLTNDSSIQTLSYVIQITNDDVNKISSNWKNNKANSLGLKKEIFMSLLIEQALDEGTQELAFLDLIRENQKQHQREHQQILVGDKRLYDILGQTLAINAKNF
What are the official names of this protein?
Uncharacterized lipoprotein MG338.
What is the protein family that this protein belongs to?
Belongs to the MG307/MG309/MG338 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: USPE_SALTI
Sequence: MAMYQNMLVVIDPNQDDQPALRRAVYLHQRIGGKIKAFLPIYDFSYEMTTLLSPDERTAMRQGVISQRTAWIREQAKYYLEAGVPIEIKVVWHNRPFEVIIQEVIAGSHDLVLKMAHQHDRLEAVIFTPTDWHLLRKCPSPVWMVKDQPWPEGGKALVAVNLASEEPYHNALNEKLVKETLQLAEQVNHTEVHLVGAYPVTPINIAIELPEFDPSVYNDAIRGQHLLAMKALRQKFSIDEKVTHVEKGLPEEVIPDLAEHLQAGIVVLGTVGRTGLSAAFLGNTAEQVIDHLRCDLLVIKPDEYQTPVELDDEDD
What is the function of this protein?
Required for resistance to DNA-damaging agents.
What are the official names of this protein?
Universal stress protein E.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein A family.
What are the subcellular locations of this protein?
Cytoplasm.