PharMolix/UniProtQA huggingface dataset:
Protein: PPIL2_NEUCR
Sequence: MGKGTDKLYITHSEWSSSDAYGASTGANAGARAQRRGASFKKLPFNFCAASLQPFKNPVCTPDGTIFDVEVIGSWLEKHKTNPVTGEPLSAKDLIKLNFARNGDTTDSDENKGDLIDPVTFKVFTDNTHIVAIRHGSYANVFAWETVERMNIKPKMWRDLVDDEEFGRRDIITLQDPQNVSASRDLSQFKYLQDGQDAILTKEQEEERKGGTVNIEALGRVGEKVLRAKEAVERARAARQAGGADVNRLTQALTTTSTNSATNNNKTAIARGQSLIQERKRPANAATYTTGLTAASFTSTGLTPSTSGSLALLSDEQYLLKPSHRIKNKGYVRMETNLGPLTLELLPEFAPKAVWNFLRLSEKGYYRDVAFHRSIRNFMIQGGDPSGTGRGGSSIWGKNFEDEFEGPNTHSARGIVSMANKGKNTNSSQFFITYRPASHLDRKHTIFAKVIEGQDTTLTAMENVATDGSDRPLNKIVIKDMIILIDPFAEWMKEKKQKEGEEERKREVARQGGTEDDRTTWTGKRIRADGTMEGQGMGEGGGGGPKVGKYLDVGAVKKAATTTTTTTRKAEEEEVDTWEEPVRKKAKMGGFGNFDGW
What is the function of this protein?
May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins.  May also function as a chaperone, playing a role in intracellular transport of proteins.  May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on proteins.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase-like 2, PPIase, Cyclophilin-60, Cyclophilin-like protein Cyp-60, RING-type E3 ubiquitin transferase isomerase-like 2, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PCRA_STAAW
Sequence: MNALLNHMNTEQSEAVKTTEGPLLIMAGAGSGKTRVLTHRIAYLLDEKDVSPYNVLAITFTNKAAREMKERVQKLVGDQAEVIWMSTFHSMCVRILRRDADRIGIERNFTIIDPTDQKSVIKDVLKNENIDSKKFEPRMFIGAISNLKNELKTPADAQKEATDYHSQMVATVYSGYQRQLSRNEALDFDDLIMTTINLFERVPEVLEYYQNKFQYIHVDEYQDTNKAQYTLVKLLASKFKNLCVVGDSDQSIYGWRGADIQNILSFEKDYPEANTIFLEQNYRSTKTILNAANEVIKNNSERKPKGLWTANTNGEKIHYYEAMTERDEAEFVIREIMKHQRNGKKYQDMAILYRTNAQSRVLEETFMKSNMPYTMVGGQKFYDRKEIKDLLSYLRIIANSNDDISLQRIINVPKRGVGPSSVEKVQNYALQNNISMFDALGEADFIGLSKKVTQECLNFYELIQSLIKEQEFLEIHEIVDEVLQKSGYREMLERENTLESRSRLENIDEFMSVPKDYEENTPLEEQSLINFLTDLSLVADIDEADTENGVTLMTMHSAKGLEFPIVFIMGMEESLFPHIRAIKSEDDHEMQEERRICYVAITRAEEVLYITHATSRMLFGRPQSNMPSRFLKEIPESLLENHSSGKRQTIQPKAKPFAKRGFSQRTTSTKKQVLSSDWNVGDKVMHKAWGEGMVSNVNEKNGSIELDIIFKSQGPKRLLAQFAPIEKKED
What is the function of this protein?
Essential helicase.
What are the official names of this protein?
ATP-dependent DNA helicase PcrA, DNA 3'-5' helicase PcrA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. UvrD subfamily.
Protein: ACEK_ECOLC
Sequence: MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAAFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDLPLRLRWQNKSRDIHYIIRHLTETLGTDNLAESHLQVANELFYRNKAAWLVGKLITSSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMELLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSVRYGEMLF
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYC_PICAN
Sequence: MAQVEDYSSLHRLRKNSEILSNANKILVANRGEIPIRIFRSAHELSMQTVAIYSHEDRLSMHRLKADEAYVIGARGQYSPVQAYLQIDEIINIALEHNVSMIHPGYGFLSENSEFARKVEDSGMIWIGPPHNVIDAVGDKVSARNLAGKCNVPVVPGTDGPIDSVEQAQEFVDKYGYPVIIKAAFGGGGRGMRVVREGESIADAFQRATSEAKTAFGNGTCFIERFLDKPKHIEVQLLADNYGNVIHLFERDCSVQRRHQKVVEIAPAKTLPVEVRDAILTDAVKLAKAANYRNAGTAEFLVDNQNRHYFIEINPRIQVEHTITEEVTGVDIVAAQIQIAAGASLQQLGLLQDKITTRGFAIQCRITTEDPAKNFQPDTGKIEVYRSSGGNGVRLDGGNGFAGAIISPHYDSMLVKCSTSGSNYEIARRKMIRALVEFRIRGVKTNIPFLLALLTHPTFVSGDCWTTFIDDTPSLFEMVQSKNRAQKLLSYLADLCVNGSSIKGQIGLPKLTRDADIPVIHDINGWDIDIKNTPPPESFRQYLLDYGPEQFANQIRAFDGCLIMDTTWRDAHQSLLATRVRTIDLLNIAPATAHAFRYAFALECWGGATFDVAMRFLHEDPWDRLRKLRKAVPNIPFQMLLRGANGVAYSSLPDNAIDHFVKQAKDAGVDIFRVFDALNDLEQLKVGVDAVKKAGGVVEATVCYSGDMLKPGKKYNLKYYLETVDKIMEMGTHLLGIKDMAGTLKPAAAKLLISSIRKKYPSVPIHVHTHDSAGTGVITYVACALAGADVVDCAVNSMSGLTSQPSMSAFIAALDNEINTGITEQNAREIDAYWSEMRLLYSCFEADLKGPDPEVYNHEIPGGQLTNLLFQAQQVGLGEKWLETKKAYEEANMLLGDIVKVTPTSKVVGDLAQFMVSNKLSPKDVERLASELDFPDSVLDFFEGLMGTPYGGFPEPLRTNILAGKRRKLTRRPGLELEPFDLKKIKEELQSRFGNSITECDVASYNMYPKVFESFKKIQEKYGDLSVLPTRFFLAPPKLNEEISVEIEQGKTFVIKVMAIGDLSPQTGTREVYFEFNGEMRKVTVEDKLAAVETVTRPKADAHNPNEVGAPMAGVVIEVRVHPGVEVKKGDPLCVLSAMKMEMVISSPVSGRVGEVIVHENDSVDAGDLICKITK
What is the function of this protein?
Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
What are the official names of this protein?
Pyruvate carboxylase, Pyruvic carboxylase, PCB.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_HAEDU
Sequence: MIGLIQRVKSANVRVEQQIVGQIEQGLLVLLGVKQGDDQSKADKLLQKVLNYRVFADQQGKMNLNVQQAGGSLLIVSQFTLAADTQKGLRPSFSRGASPADAKALYDYFHQQAALHIHTETGQFAADMQVSLQNDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S45A3_MACFA
Sequence: MVQRLWVSRLLRHRKAQLLLINLLTFGLEVCLAAGITYVPPLLLEVGVEEKFMTMVLGIGPVLGLVSVPLLGSASDHWRGRYGRRRPFIWALSLGILLSLFLIPRAGWLAGLLCPDPRPLELALLILGVGLLDFCGQVCFTPLEALLSDLFRDPDHCRQAYSVYAFMISLGGCLGYLLPAIDWDTSALAPYLGTQEECLFGLLTLIFLTCVAATLLVAEEAALGPAEPAEGLSAPSLPSHCCPCWARLAFRNLGALLPRLHQLCCRMPRTLRRLFVAELCSWMALMTFTLFYTDFVGEGLYQGVPRAELGTEARRHYDEGVRMGSLGLFLQCAISLVFSLVMDRLVQRFGTRAVYLASVAAFPVAAGATCLSHSVAVVTASAALTGFTFSALQILPYTLASLYHRERQVFLPKYRGDAGGTSSEDSLMTSFLPGPKPGAPFPNGHVGAGGSGLLPPPPALCGASACDVSVRVVVGEPTEARVVPGRGICLDLAILDSAFLLSQVAPSLFMGSIVQLSQSVTAYMVSAAGLGLVAIYFATQVVFDKSDLAKYSV
What is the function of this protein?
Proton-associated sucrose transporter.  May be able to transport also glucose and fructose.
What are the official names of this protein?
Solute carrier family 45 member 3, Prostate cancer-associated protein 6, Prostein.
What is the protein family that this protein belongs to?
Belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LEPA_CORA7
Sequence: MSTNFAATTFTDPSKIRNFCIIAHIDHGKSTLADRILQLSQVVEERDMRDQYLDNMDIERERGITIKAQNVRLPWIPRSGEFEGQEIVMQMIDTPGHVDFTYEVSRALEACEGAILLVDAAQGIEAQTLANLYLAMENDLEIIPVLNKIDLPAADPEKYALEIAHIIGCEPEEVLRVSGKTGEGVPELLDKVAELIPAPTSEFGEDAPARAMVFDSVYDTYRGVVTYIRMMDGKLTPRQKVTMMATGTNHELLEVGIVSPTMQKCKGLGPGEVGYLITGVKNVRETKVGDTITWASNGASEPLKGYADPNPMVYSGLFPISQADFPDLRDALEKLQLNDASLTFEPETSVALGFGFRCGFLGLLHMEITRDRLEREFGLDLISTAPSVTYRVVAEDGEESMVHNPSDWPGGKLREVYEPIVKMTIIVPEEFVGSTMELCQSKRGQMGGMDYLSEDRVELRYTMPLGEIIFDFFDMLKSRTKGYASLNYEEAGEQLADLVKVDILLNGDPVDAFSAIVHRDSAQWYGNKMTKKLKELIPRQQFEVPVQAAIGSKIIARENIRAMRKDVLAKCYGGDISRKRKLLEKQKAGKKRMKSIGSVSVPQEAFVAALSTDAE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y1157_STAA9
Sequence: MEYEYPIDLDWSNEEMISVINFFNHVEKYYESGVTAGDFMGAYKRFKEIVPAKAEEKQIFNTFEKSSGYNSYKAVQDVKTHSEEQRVTAKK
What are the official names of this protein?
UPF0223 protein SaurJH9_1157.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: PGK_HALH5
Sequence: MNKQSVRDVELQGKKVFCRVDFNVPMKDGVVTDDTRIRAALPTIQLLAEKGARIILASHLGRPKGEVVEELRLDPVAARLQELLGKPVAKVNVAHGPEAEQAANELKDGDVLLLENVRFYPGEEKNDPELAKAFASLADVYVNDAFGAAHRAHASTEGIAHHVTAVAGLLMEKELEVLGKALSNPERPFTAIIGGAKVKDKIGVIENLLDKVDNLIIGGGLAYTFIKAQGHEIGKSLLEADKMDLALSFMEKAKEKGVNFYVPQDAIVADDFSNDANTKAVDIDQIPADWEALDIGPKTRETYRNVIQSSKLVIWNGPMGVFELDAFAGGTKAVAEALADANDTYSVIGGGDSAAAVEKFGLANQMSHISTGGGASLEFMEGKALPGVVALNDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
Protein: ATPB_SORC5
Sequence: MVVGKITQVIGPVVDVDFPAGQLPKILNALKLSNPSISAEPDNLVLEVAQHLGESSVRTIAMDSTDGLVRGMEVRDTGKPIMVPVGNECLGRILNVVGVPIDEAGPVHAKKVAPIHREPPPFIEQSTKVEVFETGIKVIDLIAPYRKGGKIGLFGGAGVGKTVLILELINNVAKAHGGVSVFAGVGERTREGNDLFLEMSESKLADGSPVISKAALIYGQMNEPPGARSRVALSALAVAEHFRDEEGQDVLLFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLSTEMGAFQERITSTTKGSVTSVQAIYVPADDLTDPAPATAFAHLDATTVLSRAISELGIYPAVDPLDSNSTMLDPQIVGEKHYSVARRVQQTLQRYKDLQDIIAILGMDELSEDDKLVVARARKIQKFLSQPFFVAAQFTGLEGKLVPLKDTIAGFEEILDGKLDHVAEQDFYLVGGIEDVKAKASQRAS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GDAP1_BOVIN
Sequence: MARRQDEQRGGAPLIAEGKSDAEVKLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSTGEVPVLIHGENIICEATQIIDYLEQTFLDEKTPRLMPDKGSMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGRQPWLCGESFTLADVSLAVTLHRLKFLGFARRNWGNGKRPNLETYYERVLKRKTFNKVLGHVNNILISAVLPTAFRVAKKRAPKVLGTTLVVGLLAGMGYFAFMLFRKRLGSMILALRPRPNYF
What is the function of this protein?
Regulates the mitochondrial network by promoting mitochondrial fission.
What are the official names of this protein?
Ganglioside-induced differentiation-associated protein 1, GDAP1.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Cytoplasm.
Protein: YAD8_SCHPO
Sequence: MDVQTLMAASAGAVASRLLCHPIDTITVHKQTIGKFSFKTMPLKAYYRGLPISLTLITPATCLYLSTYVEAKRRFKPSVGEGAILYSICGMTAEVVSSFVWTPLEVIKARTQISQKGSVINTISTLARSEGLKGFYRGYWMGVAIYLPTTVSWWVCYEESKKYLQKQSNWDISVIAPICSALGTVVATTISTPLDIVKTRYQVATSSAMRKAEYGLQAEKELGILEIAKLLFSKHGVKGFTRGLFTRMCYIMPSGMISMSVFESFKSKDID
What are the official names of this protein?
Uncharacterized mitochondrial carrier C4G8.08.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y025_BACCR
Sequence: MMRGGMGNMNNMMKQMQKMQKDMAKAQEELGEKTVEGTAGGGMITVIANGHKQILEVKIKEEVVDPEDIEMLQDLVLAATNDALKKADELSNSTMGKFTKGLNLPGGMF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein BC_0025.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: O16I_CONEA
Sequence: TRSGGACNSHDQCCINFCRKATSTCM
What are the official names of this protein?
Conotoxin Eb6.18.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FPG_BAUCH
Sequence: MPELPEVEIIRRGIEPWVVGHIIQRAEIRNNQLRWPIDQEIISIHQRRVISLKRRAKYLLMQLHHGWIIIHFGMSGRLRILAHMLPPEKHDHIDLIMSNNCILRYTDPRRFGAWLWSNNLDKMSILNNLGVEPLSDQFDGHWLFTKSRNKSLLIKQFLMTNKLVVGIGNIYANEALFAAGILPSRASCSLKEQEALLLARSIKAILLSSIEEGGTTLRDFLQSDGRDGLFAKKLQVYGRHGEPCYTCGEFIQIAKYGQRSSFFCPSCQN
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: TRM1_PSHV1
Sequence: MPPAPKNGSAANAWRSERNARPREVWRAIVPKNLMADDTTRRLLAVAGQLQTLLFQIELLKRCDPEVLVKRALRAKIKHNALMVLYLHSRLAGDLAAQAAHRLTVGIYCLWMWLRRACSEAAALANEIDTYATYRDKDRFFSATMNLSPGGTCRLHSLVGLSLYGRTQDVTRELGLINDAENLLKQINYCHLIVSTESAEAALVGVDEFLTATVGGGMVASPETYDHTQPCCICLDELSVTANQGDTIYKRLGYSVCDHLVKQVKVNVTPDDVLRHMPFLNSVDANTLRGAIDKLRGSSGGEVGGGRRLAGVVPTGCRAEVGRSEQEDGAPAGDDRADLEHEARASRILDSYDVFTEAPGPVYRLSELRYWLASGKAAGAKTRGSCAHATHQATVLQKLDTDLSAMFARAETFERECRSAEREIFGTSFAHFHRHVASKIASVRGVGGGGEALIDKLLAGSPATAPEAEIETLISSCYSHHMSLPLFSRLGNPEKADTDALVEILKSYRDQTRPRADKAGGRAEDGAGDCDDEGYPGAADATRRGQRDWIGRVRVDTAAVADEHEDKVKKLLDRAERDLTTRRKNYAERLSARSFSNLDRCVKNQRAELEKLLRVNVYGAALPAMYVELKNGFLARQAFMKAVTSDESQHIRRCRLAREDVEGYEQHQYVRSALMRTSLDPAALPHLASRFYELVSGPMFRRHVERFPQPPNTSLYFTVENVGLLPHLKEELASFTRTYAHAEWMVSEFREFYDFSGISGVSETQRAAYAYIREAVFAAALFESIFQCGRAKLMRADSVEVDAGGPLLTDGIYLTFEERFPLIAIWGVGEDRRLCATSVVVTEKDLYAVLYAVLHKQDK
What is the function of this protein?
Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging.  Forms a tripartite terminase complex together with TRM2 and TRM3 in the host cytoplasm.  Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.  This portal forms a ring in which genomic DNA is translocated into the capsid.  TRM1 carries an endonuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.
What are the official names of this protein?
Tripartite terminase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRM1 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Found associated with the external surface of the viral capsid during assembly and DNA packaging, but seems absent in extracellular mature virions.
Protein: IF4A_CRYNJ
Sequence: MSDTKGAAEQGLQIDGDLINSNWNEVVDNFDDMKLKGELLRGIYAYGFERPSAIQQRAIMPIVTGRDCIAQAQSGTGKTATFSVSILQRIDTTVKKTQALVLAPTRELAQQIQKVVIALGDYLNVDCHACVGGTAVREDIARLNEGPHIVVGTPGRVFDMINRGALKTEAVMMFCLDEADEMLSTGFKESIYEIFQLLPGETQVVLLSATMAPEVLDVTKKFMRDPIRILVKKDELTLEGIRQFYINVEKEEWKLETLCDLYETVTITQAVIFCSTRRKVDWLTQQLHDRQFTVSAMHGDMKQEEREVIMKEFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPSSKENYIHRIGRGGRFGRKGVAINFVSNEDKNMLEEIETYYNTQVEEMPLNVADLI
What is the function of this protein?
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.  In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase eIF4A, Eukaryotic initiation factor 4A, eIF-4A, Translation initiation factor 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. eIF4A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3H_YARLI
Sequence: MTTTRVCIDSSVALKIVRHCQESAPSIVAGQLLGLDVDGELRISHAFAFPQNAAGGNPNSDDGLSLRLKAVAKYQPEMIDHLKEVNVDSNSVGWYQSTVLGRIYNASVIENLAVFQEKNPDSVVLVYDVAGSEVVSDTDPSSTGPQGHTTTTPSGFNLRAFRLSEEYLNVRKSGKFDTATLTENNLTYHDVLVELPVEIKNSNLATLLLYQLGQQYPNSPFAESSFSNLNVSVDPFLEKNIEAIFDSVDDFHYDQGNYNYYQRQMTREQAKITQWQQKRKAENAAREKDGRPALPTDEWKRLFKLPTEPSRQDNLLISAQLNEHCSVIEEFGAAVNSKLFATQGGLL
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit H, eIF3h.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOUA_BACSU
Sequence: MAFLNQDGDKYTSAKDDGTGNPITAVSIERSTVPLEVGLNNDQPLNVNVANTALDVNITNTASVPVLVKNTAAIKTQVQKSYSEFVVTDADTVATGATKSYTVDLIDSLGVFRTYGVAMYTTQTDSSNSKVLASIYSVPKNIPFYSATTSGNDNSVLFNSIVFVQNYPLQKQLTFTAPKIHLTVKAAGTVDLTGLKIVVWGME
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YouA.
Protein: UL11P_HCMVA
Sequence: MLLRYITFHREKVLYLAIACFFGIYISFHDACILVPAKVGTNVTLNAVHVHDGDYVYWSFGGGGANRLMCRYTPRLDEIHKNTNRSFSCLTNHSLLLINVTEEYTDYYRTMTTFVHQSHNWHNHGNKWTLDTCYYVYVTQNGTLPTTTTKKPTTTTRTTTTTTTKKTTTTSTTTTTTTTKKTTTSTTHHRHSNPKESTTPKTHVELHVGLGATAAETPLQPSPQYQHVATHALWVLAVVIVIIIIIIFYFRIPQKLWLLWQHDKHGIVLIPQTDL
What is the function of this protein?
Plays a role in the modulation of host immune response by modulating T-cell function.  Interacts with host PTPRC/CD45 and thereby reduces host TCR signaling and T-cell proliferation.
What are the official names of this protein?
Protein UL11.
What is the protein family that this protein belongs to?
Belongs to the RL11 family.
What are the subcellular locations of this protein?
Host cell membrane; Single-pass type I membrane protein. Host endoplasmic reticulum. Note=Localizes to the host cell membrane when highly glycosylated while less glycosylated forms are found on the endoplasmic reticulum.
Protein: POTA_BACHK
Sequence: MKKIIKVEAVEKHFGNQVIIPPLSLDIKEGEFLTILGPSGCGKTTLLRMIAGFETPTKGNLLLDDEKINDLPPYKRHMNLVFQHYALFPHMNVEKNICFGMKMQKVPAAEQKERAEEAMRLTQLLEFRNRKPAKLSGGQQQRVAIARAIVNNPRVLLLDEPLGALDFKLRKDLQRELKNLQRNLGITFIYVTHDQEEAMSMSDRIVVMNKGHIEQIGTPKEIYNKPKTLFVATFIGENNIVKNGEGYVAIRPENVKVRSVEERILKEYHLGHIEDIEFVGNMEKLYVRDEKTSELLMAYQTAEEAAQWSIGDNVYVGWEQEDEVTLN
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ARC3_ARATH
Sequence: MPISMELPVFSTLRVPLFSRLALLPTFGVPFSSLGATTRLNCTSRKARRICVMCLVRDSAPIETCERAGEDGSDEFIEVLVIGSRKESIMDSCLDSPFPSLPLRFWSISKDSSGGLVLQQRLNHQDNALKTMNPIELLQSRPRAFILVASAGYGSDQVEAINILSAVRSGGNLAVAVLLKPFSFEGRKRLEEVNELARKLQQHTNFCIDIDIEVLLQKDLVTLDEALRNANNAVSMAINAASALISGMHGNFIDVMHKDLKELEGSEVKTILESYKEAKVGFGVGHNLKTSILRAIYDCPFFRPGLKDLNAIICIVASSVPLQKKDVKTILRTFRQTMEYTGDIIVSTVHEPDLEPKVRVTTFFILSSSEVETSNKGNIFSGLVPFVLNIFTRYRSQLQKETNIGLGETPVSIKDSADSTDVKTSNQNIEEFEIDSEDLLEVSENGDDSEYPLKEGEPSRNSRLDLKDENVEDFGAIQREPIANWSMDQGYQIEQKWQADSGDTAVLSLGIVNLPVGVRPSKKLNSNLSVASQLSRKADSREESFFNPNGSTKDSSDTASTLLSEKYADFTKQRNLSARASSMLEAERDSSKRWSPILEMQYRGGLFKGRCQGGLPEGKGRLVLGDGSIYDGMWHNGKRSGLGTFYFKNGDVFQGTWREDLIHGKGWFYFHKGDRWFANFWKGKASGEGRFYSKSGEIFFGHFKDGWRHGQFLCIDLDGTRYSETWDDGVLIDRKQVDAGD
What is the function of this protein?
Together with MIND1 and MCD1, regulates FtsZ ring positioning in chloroplasts in an ARC6-dependent manner (PubMed:29967285).  Z-ring accessory protein involved in the initiation of plastid division and division site placement (might functionally replace bacterial MinC) (PubMed:23936263).  Acts as a disassembly factor that accelerates fragmentation and depolymerization of existing FtsZ2 filaments by enhancing FTSZ2 GTPase activity, thus leading to the conversion of FTSZ2 bound GTP into GDP, a process which triggers FtsZ2 filaments destabilization (PubMed:29138260, PubMed:25731613).  Prevents misplaced Z-ring formation at chloroplast stroma nondivision sites (PubMed:30824505).  May control the rate of chloroplast expansion.  Seems to influence stromule (stroma-filled tubular extensions of the plastid envelope membrane) length and frequency.
What are the official names of this protein?
Protein ACCUMULATION AND REPLICATION OF CHLOROPLASTS 3, chloroplastic.
What are the subcellular locations of this protein?
Plastid, chloroplast outer membrane; Peripheral membrane protein; Cytoplasmic side. Plastid, chloroplast stroma. Note=Distributed in two pools, a first one throughout the stroma, probably to inhibits Z-ring assembly at nondivision sites, and a second one localized to a midplastid ring-like structure (PubMed:30824505). Located at the site of chloroplast division on the outer surface in a ring-shaped structure at the early and middle stages of the process according to PubMed:15356321. Forms ring-like structures, short filaments and discrete foci in the chloroplast stroma according to PubMed:17304239 (PubMed:17304239, PubMed:15356321).
Protein: NIFH_DECAR
Sequence: MAKLRQCAIYGKGGIGKSTTTQNLVAALAESGKKVMIVGCDPKADSTRLILHSKAQTTVMHLAAEAGSVEDLELEDVLSVGFGGIKCVESGGPEPGVGCAGRGVITAINFLEEEGAYDEDLDFVFYDVLGDVVCGGFAMPIRENKAQEIYIVCSGEMMAMYAANNIAKGIVKYANSGGVRLAGLICNSRNTDREDELIMALAGRLGTTMIHFVPRDNAVQHAEIRRMTMVEYDPKHKQADEYRQLANKIVNNTNFVIPTPIEMEELEELLMEFGIMEAEDESIVGQTAAELAAAAA
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
What are the official names of this protein?
Nitrogenase iron protein, Nitrogenase Fe protein, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.