PharMolix/UniProtQA huggingface dataset:
Protein: APGM_THEGJ
Sequence: MKKRKGLLIILDGLGDRPIKEFGGKTPLEYAKTPNMDKLAKLGILGQQDPIKPGQPAGSDTAHLSIFGYDPYKVYRGRGFLEALGVGLDLDEDDLAFRVNFATIENGIITDRRAGRISTEEAHELAKAIQENVKLPVDFIFVGATGHRAVLVLKGMAKGYRVGENDPHEAGKPPHRFTWEDEESKRVAEILEEFVRQAHEVLERHPINEKRRKEGKPVANYLLIRGAGTYPDIPMKFTEQWKVRAGAVIAVSLVKGVARAIGFDVYTPEGATGEYNTDEMAKAKKTVELLKEYDFVFLHFKPTDAAGHDNNPKLKAEMIEKADRMIGYIIEHINLEDVVIAITGDHSTPCEVMNHSGDPVPLLIVGGGVRPDHTESFGERECMRGGLGRIRGHDIVPVMMDLMNRSEKFGA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, aPGAM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
Protein: CHLB_NEPEX
Sequence: KRLLGESGIAVNQVIPEGGYLNYLKDLPRAWFNIVPYREVGLMTAIFSEKEYGMPYISITPMGISNTANFIAQIEKLVNMWASALSEKRLNYKFYVDNQTKFV
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex (By similarity).
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IREB2_XENTR
Sequence: MTENPFHYLVEPLSGTSDKTFFNVSKLKATEYDSLPYCIRVVLEAVVRNCDGVLVKEQDAFNILNWKATCEFKEIPFLPARVMLQDFTGIPAMVDFAAMRDAISKFGRDPKQVNPACPTDLIADHSLQLDFTKCIVAQNVSSVPTVETHKPTTKQSPGKTLGRKAQCRSQSGCKGACELGAAHGSSREQIENTPMLCPFHLQPIAEPEAALKSLEIEFNRNKERLQFFKWCTKAFHNVAVIPPETGTVHQVNLEFLSRVVMEEKGFIYPDSVLGTDSHTTMVNGLGILGLGVGGIESEAAMLGVPITLTLPEVIGCELTGAINPLATSIDVVLSITKHLKQAGVAGTFVEFFGNGVSQLSVADRTTIANMCPEYGATVAFFPVDSVTLRHLKQTGVDVQSVSTFETYLQAVKLLRQENVQQPEYSKVLQINLNSIVPYVSGPKRPQDRISVMDMKKDFEACLNEKTGLKGFQIPEKKQSIMVPVTYENSEYSLSHGCVVIAAVTSCTNNCNPSVMLTAGLLAKKAVEAGLTVKPYIKTSLSPGSGTVTYYLSASGVLPYLSKLGFDIIGYGCARCVGNTNPLPESIVTAIKEGELVACGVFSGNKHFEGNRCSCVCANYLASPPLVVAYALAGTVNIDLQTEALGENAQGEKIFLRDIWPSREEVLEVEETMVIPSMFSELKLKIEKQNTRWNLLDAPESTLFPWDLRSTFIRSPPFFHKLEKIPPPIQPIEKAHVLLYLGDSVTTDHMSPAGSIPRTSPAAKYLIQKNLIPREFNSYGARRGNDAVMTRGTFANMKLFNKLVGKTGPKTFHLPSGQIMDVFDAAELYQKAEIPLIIIAGKKYGLGNSRDWAAKGPFLLGVRVVIAESYEKIHKDHLVGMGIAPLQFLSGENAETLGLSAKEQYSFSLPVDLTPRHKIEVKTNTGKTFHVIAAFDNEAEVTFYKHGGILSYVARKYL
What is the function of this protein?
RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA.  Binding to the IRE element in ferritin results in the repression of its mRNA translation.  Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
What are the official names of this protein?
Iron-responsive element-binding protein 2, IRE-BP 2.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFR3_NEUCR
Sequence: MNALQQKCRPKHQVLVLKCYPRTIKGAVDVKPNSSELSYLLFYCQSRRAKIQKVGSFLEKKTASDVYHQRIGNVQVTLQILAALIEKSPKDLPLFASCVLSILEQVLKSSDITMVESSIPTFQAFCENHDPTSLAADQAYFRQYVSVVQQYASLASTRPAPGKAQHSKPIALRWRNAGLEAIRSVASSDALSSMVARQYDILVPMILENLWTENEDFLDVLLQRVQGDNNVEDAPLLRRRTSNATAQPSETTGGEPGPNPIAFLGTAVDVDKLAEEDIGVLAMQCLRQVFVAPSRSQTHNPTIALLRFIEERVDQNEQVVKRDAHGKDNGWAIKVFLMAARWAPVADRFTILLTAIEVLTQRPLTDDNLRHHNTQAAMISALLRSDVNLIGLSVMDVLLNLLRHMQRLVQMPGDPDSMRVEDETIGTDEGAIGQRRELLFRLQQCVGDLATHVYYADQISDMIQTILLKLRPSRPTSPPNSSPNGERSDNGAAEDQPLESLFALTVAKIAALKAIKAILWVASPRTKMSGGHINLSRNRVPIQTWDGTQWLLRDPDGLVRKAYVDAVVTWLDRETTPADSLARDESARTTLKNRAAQENNLARRVVSSASARVDKSANAPRSHFLQLLHLAIYDHALQFVDYENDLVLLHVLLAKLVSQLGVNAAKFGIPMIFRLQEDIQDVETPLGKVRIGSLVHGYLWTLTEKFDCEGTAPGSAIHGEIIRRRSKNFWVEGINIPAPAVDLVGTPGQARPPPQMNMRDLESEALLPFDERASLVDCICTGYQELATSPPTSPTTSPGRNFTHPMLGSTLSATPKDETQREVPAQFRELMLGDWTREAVLANTQAGSSQTASLNGTNGTHRNTVNNNNRLGVNGVTSPNGSNSNLRPSSSPTGPNGVQAGRTRKTSIRSNGGGGSPAHSTYRAKAQQPVTSVEQLKAVLSGHLQPPPTSHGINFQHSDDSDDSLVSYDMAPSELSFNPAASGSRQGSPGNTSQAASSPPRRTSQDRTQQLKFGGPLVPGEESVVNGAGGQEGSNGAAGNLGVPISRTTSRTQPQATTAHTTLPRPSTSSKRSIKSRAGSRAGPMSSSWLGEKPPAMDLAALLKGIDSASISDIKSLGAGGKPPY
What are the official names of this protein?
Protein efr-3.
What is the protein family that this protein belongs to?
Belongs to the EFR3 family.
Protein: HEMO_PONAB
Sequence: MARALGAPIALGLWSLCWSLAIATPLPPTSAHGNVAEGETKPDPDVTERCSDGWSFDATTLDDNGTMLFFKGEFVWKSHKWDRELISERWKNFPSPVDAAFRQGHNSVFLIKGDKVWVYPPEKKEKGYPKLLQDEFPGIPSPLDAAVECHRGECQAEGVLFFQGDREWFWDLATGTMKERSWPAVGNCSSALRWLGRYYCFQGNQFLRFDPVRGEVPPRYPRDVRDYFMPCPGRGHGHRNGTGHGNGTHHGPEYMRCSPHLVLSALTSDNHGATYAFSGTHYWRLDTSRDGWHSWPIAHQWPQGPSTVDAAFSWEEKLYLVQGTQVYVFLTKGGYTLVSGYPKQLEKEVGTPHGIILDSVDAAFICPGSSRLHIMAGRRLWWLDLKSGAQALWTELPWPHEKVDGALCVEKSLGPNSCSANGPGLYLIHGPNLYCYSDVEKLNAAKALPQPQNVTSLLGCTH
What is the function of this protein?
Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
What are the official names of this protein?
Hemopexin.
What is the protein family that this protein belongs to?
Belongs to the hemopexin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL20_SALPC
Sequence: MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFDKVAFTALVEKAKAALA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: TRPA_CHLP8
Sequence: MKENRITRLMKQDKKLLLAYYMPEFPVPGATLPVLEALQENGADIIELGMPYSDPIGDGPVIQDAAHKAISHGVTVRSILDLVKQARAGEGCKKITTPILLMGYSNPLIAYGGDCFMADAVEAGVDGLLIPDLPPEESEDFLERARSFGLTVVYLISPVTPPDRIELIDCMSTDFSYCLAVNATTGTGKLDTAGMDEQIAEYLKRVRKHAKKKFVVGFGIKDRERVRKMWELADGAVVGSALLQQVASAKTPEETAAMAAEFWQSLR
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: TX482_HYSGI
Sequence: GVDKAGCRYMFGGCSVNDDCCPRLGCHSLFSYCAWDLTFSD
What is the function of this protein?
Toxin that blocks vertebrate P/Q-type (Cav2. 1/CACNA1A) and R-type (Cav2. 3/CACNA1E) voltage-gated calcium channels.  Also inhibits sodium channels (Nav) in bovine chromaffin cells by delaying sodium channel inactivation.
What are the official names of this protein?
Omega-theraphotoxin-Hg1a, Omega-TRTX-Hg1a, Toxin SNX-482, SNX482.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 56 (SNX-482) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MIAA_LIMF3
Sequence: MAKVVAIVGPTAVGKTALSLRVAQKFGGEVISGDSMQVYRGLDIGTAKATTEERSLVPHHLIDVKDIHDRFSVADFKVAAEREIDQITDRGHLPLVVGGTGFYLQALVENLALGRDQFDQESAAIRDHWHQIATERGKQFVWEQLNERDPAAAAKIPVANLRRVIRALEVIEKTGALFSTQPQPPAKNDFLIIGLTTQRPVLYQRINQRVDQMVANGLLEEAKWLYDQGGENEQAGKGIGYRELFPHFAGTVSRQEALEKIKLDSRHYAKRQLTWFRNQMTVHWFDLVSQQNTTEEIEALINGWLKK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RUVA_BURM1
Sequence: MIGRIAGILLEKNPPHLLVDCNGVGYEIDVPMSTFYNLPQTGERVVLLTQQIVREDAHLLYGFLTPQERTTFRELLKITGIGARMALAVLSGMSVQELAQAVTMQDAARLTRLPGIGKKTAERLLLELKGKLGADLGALAGAASASDHATDILNALLALGYSEKEGLAAIKNVPAGTGVSEGIKLALKALSKA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: END4_MYCBP
Sequence: MLIGSHVSPTDPLAAAEAEGADVVQIFLGNPQSWKAPKPRDDAAALKAATLPIYVHAPYLINLASANNRVRIPSRKILQETCAAAADIGAAAVIVHGGHVADDNDIDKGFQRWRKALDRLETEVPVYLENTAGGDHAMARRFDTIARLWDVIGDTGIGFCLDTCHTWAAGEALTDAVDRIKAITGRIDLVHCNDSRDEAGSGRDRHANLGSGQIDPDLLVAAVKAAGAPVICETADQGRKDDIAFLRERTGS
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: PSD_EHRRG
Sequence: MLCNLIHNIHKEGYIIIMISFLLSCIGFAISCSLGIIFLVASLLCIYFFRDPIRIVPEGDHLIISPADGIILNIEQVNSPIDNSTQVLCISIFLNVLNVHVNRIPVSGTIKATEYIPGRFISASLNKSSELNERQRIVIESNVSHHTIIVDQIAGLIARRIVCNAYEGQNVNSGERFGIIRFGSRVNIYLPLNIHISAFKGQTVIGGETILAYLEDYPHKQLTAKFI
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ATCA7_ARATH
Sequence: MVNYSSISCIFFVALFSIFTIVSISSAASSHGEVEDEREFNYKKNDEKGPERWGELKPEWEMCGKGEMQSPIDLMNERVNIVSHLGRLNRDYNPSNATLKNRGHDIMLKFEDGAGTIKINGFEYELQQLHWHSPSEHTINGRRFALELHMVHEGRNRRMAVVTVLYKIGRADTFIRSLEKELEGIAEMEEAEKNVGMIDPTKIKIGSRKYYRYTGSLTTPPCTQNVTWSVVRKVRTVTRKQVKLLRVAVHDDANSNARPVQPTNKRIVHLYRPIV
What is the function of this protein?
Reversible hydration of carbon dioxide.
What are the official names of this protein?
Alpha carbonic anhydrase 7, AtaCA7, AtalphaCA7, Alpha carbonate dehydratase 7.
What is the protein family that this protein belongs to?
Belongs to the alpha-class carbonic anhydrase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma. Note=Targeted to the chloroplast via a protein-targeting pathway that uses the secretory system.
Protein: COQ42_CULQU
Sequence: MFLRRVHPVRLGHAIQRSLTTTKSRNESTTTTVEAPQAVPSPPPDAFTEEFLRNQIKVTELQRVILGVGSSLAALVNPRRHDMIACLGETTGVPALDAIRRQMLASDEGRQILADRPRINTRTVDMAALKALPETSFGHQYVHFLEKHDITPDSRAEVRFMDDPELAYVMTRYREVHDLVHTVLGMPTNMLGEVAVKWVEALNTGLPMCYGGAVFGAFRLRPK
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ4 homolog 2, mitochondrial, Coenzyme Q biosynthesis protein 4 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: UBIA_BURP0
Sequence: MLARFPLYLRLIRMDKPIGSLLLLWPTLNALWIASDGHPAPSLVAIFALGTLLMRSAGCAINDYADRDFDRHVKRTAERPLTSGKIRAWEAIAIAVGLALVSFLLILPLNGLTKELSVVAVFVAATYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTVPMIAWAMLAANVFWSVAYDTAYAMVDRDDDLKIGMRTSAITFGRHDVLAIMLCYAAMLGIYVWLGAALHFGWPYWAGWAAAAGCSIYHYTLIKDRERMACFAAFRHNNWLGGVLFAGIAAHYALAVR
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL27_STRZT
Sequence: MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTGGSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: SPEH_LEPIC
Sequence: MNALGKHVIAEFYECDYETINNHELVEDIMLKSVDLSGATTIKSVFHRFSPYGVSGVVVVSESHFAIHTWPEYGYCAVDVFTCGDLIDNQAALDYLKEKFGSKNVSVVEMKRGVLNLGVDLHHKPVGN
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: EST5A_DROPS
Sequence: MHLVRWLICLIQLWVQLGAAGSVTLLDPLLIEIPNGKLRGRDNGHYYSYEAIPYAEPPTGELRFEVPKPYKQQWTNTFDATQPPVLCMQWNQFINGTNKLLGVEDCLTVSVYRPKNSSRNNFPVVANLHGGAFMFGGPSQYGHENIMREGSVILVTIGYRLGPLGFVSTGDADLSGNFGLKDQRLALLWIKQNIASFGGEPENILVVGHSAGGASVHLQMLREDFSKLAKAAISFSGNALDPWVIQQGLRGRAFELGRIVGCGQASDSGTLKKCLKSKPAIEIVSAVRSFLVFSYVPFTPFGPAIESPDAPEAFITQHPIDIIKSGKFSQVPWAVTYTTEDGGYNAALLLEKQASSGRELIVDLNDRWFDWAPYLLFYRDSMTTIKDMDDYSRKLRQEYLGDRRFSVESYWDVQRMFTDLLFKNSVTVSVDLHRKYGKSPVYAFVYDNPSEVGVGQILSGRNDVYFGTVHGDDVFLIFNVSFVPANRRPDEEIISRNFIKMLEYFALSTDDTMAYGDCVFQNNVGSKHMQLLSITRDGCENKQLNCFI
What are the official names of this protein?
Esterase-5A, Est-5A, Carboxylic-ester hydrolase 5A, Carboxylesterase-5A.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: HTPX_CITK8
Sequence: MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSVQGLLIMALLFGFGGSFISLLMSKWMALKSVGGEVIEQPRNERERWLMNTVATQARQAGIAMPQVAIYHAPDINAFATGARRDASLVAVSTGLLQNMSPDEAEAVIAHEISHIANGDMVTMTLIQGVVNTFVIFISRIIAQIAAGFLGGNRDEGESSNGNPMIYFAVAMVLELVFGILASIITMWFSRHREFHADAGSAKLVGREKMIAALQRLKTSYEPQEANSMMAFCINGKSKSLSELFMTHPPLDKRIEALRSGEYLK
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YK183_YEAST
Sequence: MYSKILLYRSNVLFMNFFSVFVCTIGTLFLVFADVYVLASAFFQSKKEKETKFKHLHYQKRSCFFLANIH
What are the official names of this protein?
Uncharacterized protein YKL183C-A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SYI_BRAHW
Sequence: MDYSSTINLPKTAFPMKAGLKEKEPKIIKKWEEEKLYQQLRELRKGAPKCILHDGPPYANGDIHIGTSLNKIIKDIIVRYKSAKGFDSPYVPGWDCHGMPIELKVQESLGDKYKETSKFIMRKKCRAYAQKYIDIQRKEFKRLGVMGDWENPYLTMSPEYESEIVEVFAQLVEKGYIYKGLRTIHWCMDCETALAAAEIEYDDNHTSTSVYVRFPVLNKINDKLDGNVDVMIWTTTPWTLPSNMACAFNRDLEYVAVEIDGRYAIMTTSLVDTVLSKKDMKAEGRDMIPVSMEDIEKLEIAHPFIKDRKSAVVFADYVEATAGTGIVHTAPGHGMEDYQTGMNYGLEIYCPVDKAGRYTSDFPEMQGMKVRDANPKVVEILENNGSLYHKEKVTHSYPICWRCKNPLIFRATSQWFMNMTHDDIDKRTVKALDNIKWYPTWGHDRMQKMLENRPDWCLSRQRSWGVPIPAFYCKNCGKTLLTAESTRHFAEIVKTKGMDVWFELEAKDLLPEGTKCECGSTDFDKEQDILDVWFDSGVSSFAAQKTNKDLDGVFPVDIYLEGGDQYRGWFQAAIWPSMAIRGIPPYKELVTHGWTLDEQGRAMHKSAGNVVSPLEVIDKYGADILRLWCISEDFTHNARVGDNMMKAIADNYRKIRNTFRYLLGNISDFDFTKEKIEVKDLLPVDRYALSRLHSFIKVAEKACDGYEFHLFYQRLINYCVVELSATYFDIIKDRLYCDRKDSVSRRSAQTVLVEILDVLVKLIAPVLPFTTDEVWGYYKGENASSVHLELYPKADDNLIDLELEKEWTSILKVRDDVLLSLERARDNSTIGKSLEAYVTICTKEPATKELLTKYEKYLNEIFIVSKVTLSDSKDDTFIEGGVSFVKTEKASHEKCVRCWGHYDSVGTDSEHKELCTRCAEAVR
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPN_LACLM
Sequence: MAVKRLIETFVPENYKIFLDIDRKTKKIKGQVAITGEAKDTVVSFHTKGLHFNKVRAFSVDTNFIENEEDEEIVVKIGETGRVTVSFEYEAELTDNMMGIYPSYYEVNGEKKMLIGTQFESHFARQAFPSIDEPEAKATFDLSVKFDEEEGDIIVSNMPELLNINGIHVFERTVKMSSYLLAFVFGELQYKKGKTKSGVEVGAFATKAHSQAALDFPLDIAIRSIEFYEDYYQTPYPLPHSWHIALPDFSAGAMENWGCITYREVCMLVDPENATIQSKQYVATVIAHELAHQWFGDLVTMQWWDDLWLNESFANNMEYVCMDALEPSWNVWESFSISEANMALNRDATDGVQSVHVEVTHPDEIGTLFDPAIVYAKGSRLMVMLRKWLGDEDFAAGLALYFKRHQYGNTVGDNLWDALAEVSGKDVAAFMHSWVNQPGYPVVTAEVVDDTLILSQKQFFVGEGVDKGRLWNVPLNTNWTGLPDLLSSEKVEIPGFAALKTKNNGKALFLNDANMAHYIIDYKGALLTDLLSEVESLENVTKFQILQDRKLLAKAGVISYADVVNILPSFTNEESYLVNTGLSQLISELELFVDEDSETEKAFQSLVGKLFAKNYARLGWDKVAGESAGDESLRGIVLSKTLYSENADAKTKASQIFAAHKENLASIPADIRPIVLNNEIKTTNSAELVKTYRETYIKTSLQEFKRELEGAVALIKDEKVIAELLESFKNADIVKPQDIAFSWFYLLRNDFSQDAAWAWEKANWAFLEEKLGGDMSYDKFVIYPGNTFKTADKLAEYKAFFEPKLENQGLKRSIEMAIKQITARVALIDSQKAAVDKAITDIAEKL
What is the function of this protein?
Aminopeptidase with broad substrate specificity to several peptides.  It has more affinity for oligopeptides than for dipeptides.  It plays an essential role in the metabolism, it may be involved in nitrogen supply or protein turnover.
What are the official names of this protein?
Aminopeptidase N, Alanine aminopeptidase, Lysyl aminopeptidase, Lys-AP.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=It may be secreted through an unknown mechanism.
Protein: RR9_NEOYE
Sequence: MSTELIKTRAIYSGTGRRKCSVAQVRLVPGSGNLIINGIPGESYLQFSPNYLRVSYAPLQVLGLLNQYDIHVNARGGGLTGQADAIRLGVARALCSINPENRTTLKSEGYLTRDPRVKERKKYGLKKARKAPQFSKR
What are the official names of this protein?
30S ribosomal protein S9, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ADML_HUMAN
Sequence: MKLVSVALMYLGSLAFLGADTARLDVASEFRKKWNKWALSRGKRELRMSSSYPTGLADVKAGPAQTLIRPQDMKGASRSPEDSSPDAARIRVKRYRQSMNNFQGLRSFGCRFGTCTVQKLAHQIYQFTDKDKDNVAPRSKISPQGYGRRRRRSLPEAGPGRTLVSSKPQAHGAPAPPSGSAPHFL
What is the function of this protein?
AM and PAMP are potent hypotensive and vasodilatator agents.  Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis.  In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions.  In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion.  Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels.
What are the official names of this protein?
Pro-adrenomedullin.
What is the protein family that this protein belongs to?
Belongs to the adrenomedullin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GRCA_ALIF1
Sequence: MITGIQITKAANDDLLNSIWLLDSEKNEARCVVATAGFEADQVIAASELGEYESRDVAIEKAPKIEGGQHLNVNVLQRDTLEDAVKHPENYPQLTIRVSGYAVRFNSLTTEQQKDVIARTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: DPOLL_HUMAN
Sequence: MDPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAHVVRTGIGRARAELFEKQIVQHGGQLCPAQGPGVTHIVVDEGMDYERALRLLRLPQLPPGAQLVKSAWLSLCLQERRLVDVAGFSIFIPSRYLDHPQPSKAEQDASIPPGTHEALLQTALSPPPPPTRPVSPPQKAKEAPNTQAQPISDDEASDGEETQVSAADLEALISGHYPTSLEGDCEPSPAPAVLDKWVCAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRALGYAKAINALKSFHKPVTSYQEACSIPGIGKRMAEKIIEILESGHLRKLDHISESVPVLELFSNIWGAGTKTAQMWYQQGFRSLEDIRSQASLTTQQAIGLKHYSDFLERMPREEATEIEQTVQKAAQAFNSGLLCVACGSYRRGKATCGDVDVLITHPDGRSHRGIFSRLLDSLRQEGFLTDDLVSQEENGQQQKYLGVCRLPGPGRRHRRLDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHALSTAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYREPAERDW
What is the function of this protein?
DNA polymerase that functions in several pathways of DNA repair (PubMed:11457865, PubMed:19806195, PubMed:20693240, PubMed:30250067).  Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA (PubMed:11457865, PubMed:19806195).  Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination (PubMed:19806195, PubMed:20693240, PubMed:30250067).  Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities (PubMed:10982892, PubMed:10887191, PubMed:12809503, PubMed:14627824, PubMed:15537631, PubMed:19806195).  Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity (PubMed:11457865, PubMed:19806195).
What are the official names of this protein?
DNA polymerase lambda, Pol Lambda, DNA polymerase beta-2, Pol beta2, DNA polymerase kappa.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-X family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Accumulates at sites of DNA damage.
Protein: DEF_ECOLC
Sequence: MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVEKLDRLKARA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: DSE3_CANGA
Sequence: MPRKFLGEKIDRNTDFLRPSSLTLTADDLKVIPDFKCDDDDAVLSGNKTGKRLSRKFGGTMRLKQRLESVPELFLHDFRKRRGQKLQERNNDEQISRAKLPPHLSGLRRPNGLPARKPLRTITEVLPPVTSYNNSIEQNEDDLYYVEKKDPKEHVVETNHKEMRPLDKPLIEKVENVYLEPLIFPVQVSEPVNQMSIPMEELQKYGKSDSEILFDEIISAYEPHMETTGDVSNVLNSEILSVLDRVSNAPKKNWNLMAPKVISAEAIEENKRLSINSIASSGRTPESTRNSRFCENLSSPEYSTAASVSDRWSSGDEFSDVASSNPNSHAISHDGSYTTALGSIPSLAGSVDNLDILDQKDILSPTVSNEIITVKPVPQNTVETMHVTKIVIKPQLFLDWESEEEDDPIDALSRQVDNIEIASVYSGSSSVYSDHFAT
What is the function of this protein?
May be involved in the establishment of the daughter fate.
What are the official names of this protein?
Protein DSE3.
What are the subcellular locations of this protein?
Bud neck.