PharMolix/UniProtQA huggingface dataset:
Protein: EFP_SULNB
Sequence: MATIGMGDIKKGVRLELDGNPYKVTEFQHVKPGKGAAFVRVKIKNLKTGKVIEKTVHAGDKFEVPELEQKTMQYLYDDGEMLQFMDTTTFDQIGLTHEQVGKETFDFMIDGMEADILFHNGEAISVEIPQTVVLKIVETPPNFKGDSQGGKKPATLESGAVVQVPFHVLEGEMIKVDTVEGKYLEKAK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_CORJK
Sequence: MTLRIYDTAARQLRDFEPIREGHASIYLCGATVQSIPHIGHVRSGVAFDILRNWLEAKGLDVAFVRNVTDIDDKILTKAAENDRPWWEWAATHERAFNWAYDQLGVTPPSIEPRATGHVPQMIEYMQRIIDNGHGYAADGNVYAQPATIDNYGFLSGQKLDEMDQGESAGTGKRDPRDFTMWKAAKPGEPAWDTPWGRGRPGWHIECSAMATTYLGSEFDIHCGGLDLQFPHHENEAAQATAAGDGFARYWMHNGWVTMSGEKMSKSLGNVLSIPNVLKLVRPVELRYYLGSAHYRSMLEYSEAALGEAAAGYRRIEKFLVRAIEYVTGETAVDPQALPVGEMPAQFAEKMDDDLAVPQSLAVIHDVVREGNKLLDAKPTDEAKQQVKEIAGQVRAMAAVLGVDPLSEAWLESTKAAAGGSDVAMGALDVLVKAELERRAEARAAKDWATADEVRDRLAEAGIEVTDTADGAKWSLKG
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDHA_COLLI
Sequence: MSLKDQLIHNVHKEEHSHAHNKISVVGVGAVGMACAISILMKDLADELALVDVVEDKLKGEMLDLQHGSLFLRTPKIVSGKDYSVTAHSKLVIVTAGARQQEGESRLNLVQRNVNIFKVIIPNVVKYSPDCKLLIVSNPVDILTYVAWKISGFPKHRVIGSGCNLDSARFRHLMGERLGIHPLSCHGWIVGEHGDSSVPVWSGVNVAGVSLKALHPDMGTDADKEHWKEVHKQVVDSAYEVIKLKGYTSWAIGLSVADLAETIMKNLRRVHPISTVVKGMHGIKEDVFLSVPCVLGSSGITDVVKMILKPEEEDKLRKSADTLWGIQKELQF
What is the function of this protein?
Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).
What are the official names of this protein?
L-lactate dehydrogenase A chain, LDH-A.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HMG12_CAEEL
Sequence: MSDVAEEKAEFLVIRTYGSESFRKECADLIEKELHKLNATIARVPVGEFVAYAENAVKNETDSEAVGSSSVKRENSANDSPANTNDVDIVSSPVKRGRGRKAKNPSADADVNDTGSSPVKKGRGRPIKNPSADAGSPLVKKGRGRRAQTPAADTDAIDTASSPVKKGRGRPAKNPSADAGSPLVKKGRGRQAKNLAADTDAIDTASSPVKKGRGRPLKKTAAEADVNGLGSPSANRITGCPPSTKVSNQSSPPEPAVNESEEADEPVLKRGRSVKQPKDESESDDEDAEKAPAAIPKKRGRPGKSAIDAFFDGSD
What is the function of this protein?
Transcriptional regulator (PubMed:18430416).  Binds to specific sequence motifs in regulatory elements (PubMed:18430416).  May recruit transcription factors, or may induce structural changes in chromatin, to thereby modulate embryonic expression of ATP-dependent chaperone cdc-48. 1 (PubMed:18430416).
What are the official names of this protein?
High mobility group protein hmg-12, High mobility group AT-hook protein hmg-12, High mobility group protein I beta.
What is the protein family that this protein belongs to?
Belongs to the HMGA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KCNK7_HUMAN
Sequence: MGGLRPWSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLHPVIYHLGQLALLGYLLLGLLAMLLAVETFSELPQVRAMGKFFRPSGPVTAEDQGGILGQDELALSTLPPAAPASGQAPAC
What is the function of this protein?
Probable potassium channel subunit.  No channel activity observed in vitro as protein remains in the endoplasmic reticulum.  May need to associate with an as yet unknown partner in order to reach the plasma membrane.
What are the official names of this protein?
Potassium channel subfamily K member 7.
What is the protein family that this protein belongs to?
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YR125_MIMIV
Sequence: MEYDNFFIKILESLINDKITLKRQISVNIPDTDNIFGNSDLTTTLWTSQFQCPQKFHHKFFDAIKDSRGINWIRADSFIEILGFKNKPKKVLKKYVSKRYKCYLIDIDSPVKKNLIDTVFKPKTIFIRYEGLLQLISQSNNPKSVKLWEHIAQIILPNNYHKNPVNQASILQRDNRQLVIRHIEEDIYELEDDIRN
What are the official names of this protein?
Uncharacterized Bro-N domain-containing protein R125.
Protein: ODPB_CYACA
Sequence: MSMMFLYEALRAAIDEEMGKDSNVFIVGEDVGHYGGSYKVTKDLHVKYGDLRVLDAPIAENSFTGMAIGAAMTGLRPIVEGMNMGFMLLAFNQISNNLSMLQYTSGGNFNIPVVIRGPGGIGKQLAAEHSQRLESCFQSIPGLQIVACSTAYNAKGLLKSAIIEKKPILFLEHVLLYNLKGFVPDEEYYLPLDKAEVVRSGSDVTIVTYSRMRYHVLAAVEKLVLNGQDPEIIDLISLKPLDLHTISKSIKKTHKIVIVEECAQTGGIAAELISLINTYLYDELDSPAVRLSSKDVPIPYNGNLEKSTLIQPDQIVDVVTNLLQYKT
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit beta.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HEM1_SALTI
Sequence: MTLLALGINHKTAPVSLRERVTFSPDTLDQALDSLLAQPMVQGGVVLSTCNRTELYLSVEEQDNLQEALIRWLCDYHNLNEDDLRNSLYWHQDNDAVSHLMRVASGLDSLVLGEPQILGQVKKAFADSQKGHLNASALERMFQKSFSVAKRVRTETDIGASAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRERAQALADEVGAEVISLSDIDARLQDADIIISSTASPLPIIGKGMVERALKSRRNQPMLLVDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRQAAAVEAETIVEQEASEFMAWLRAQGASETIREYRSQSEQIRDELTTKALSALQQGGDAQAILQDLAWKLTNRLIHAPTKSLQQAARDGDDERLNILRDSLGLE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: SPRE3_MOUSE
Sequence: MVRVRAVVMARDDSSGGWLPVGGGGLSQVSVCRVRGARPEGGARQGHYVIHGERLRDQKTTLECTLRPGLVYNKVNPIFHHWSLGDCKFGLTFQSPAEADEFQKSLLAALAALSRGSLTPSSSSSSSSPSQDTAETPCPLTSHVDSDSSSSHSRQETPPTAPIATVESAAAFPLATRPQRRRSSAQSYPPLLPFTGIPEPSESLAGAGSQGWGSRGYEDYRRSGPPPPPLALSTCVVRFAKTGALRGAALGPPVSLPAPLTEAAPPAPPARPPPGPGPTPAPAKASPEAEEAARCVHCRALFRRRADGRGGRCAEAPDPGRLLVRRLSCLWCAESLLYHCLSDAEGDFSDPCACEPGHPRPAARWAALAALSLAVPCLCCYAPLRACHWVAARCGCAGCGGRHEEAAR
What is the function of this protein?
Tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase (PubMed:12646235).  Inhibits fibroblast growth factor (FGF)-induced retinal lens fiber differentiation, probably by inhibiting FGF-mediated phosphorylation of ERK1/2 (PubMed:29501879).  Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells (PubMed:25576668).
What are the official names of this protein?
Sprouty-related, EVH1 domain-containing protein 3, Spred-3.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GLNE_PSEPK
Sequence: MRLPLPSDLPATLQPLVTRNQQFISDAVAGHPELDLQAWSPLHRQQFDQVAAASEFVLSLAQREPAMLFALLASGELERRYAPGELRGQIAATAQAAQSEDELARNLRRARNRQQLRIIWRDITRQAELGETCRDLSDLADAAIDEAYQWLYPRHCQQFGTPIGNRSGQPQHMVVLGMGKLGAVELNLSSDIDLIFGFPEGGETEGVKRSLDNQEFFTRLGQRLIKALDPVTVDGFVFRVDMRLRPYGSAGALVLSFNALEQYYQDQGRDWERYAMIKARVVAGDQAAGAQLQEMLRPFVYRRYLDFSAIEALRTMKQLIQQEVRRKGMAENIKLGAGGIREVEFIAQAFQLIHGGRDLSLQQRPLLKVLATLEGQGYLPPAVVAELREGYEFLRYTEHAIQAIADRQTQMLPEGETDQARVAYVLGFADWQSFHDQLMYWRGRIDWHFRQVIADPDDEDGEGELVVGGEWSPLWEQAQDEEAAGRQLQEAGFKQPAEALRRLAGLRSSPQLRSMQRIGRERLDAFIPRLLAQAVEHDNPDLVLERVLPLVEAVARRSAYLVLLTENPGALRRLLTLCAASPWIAEQIALYPLLLDELLNEGRLFSPPLAPELASELRERLTRIPEDDLEQQMEALRHFKLAHSLRVAASEISGNLPLMKVSDYLTWLAEAILDQVLALAWRQTVARHGQPKRSDGSLCDPGFIIIGYGKMGGLELGHGSDLDLVFIHDGDPQAETDGAKPIDSAQFFTRLGQRIIHLLTTQTNSGQLYDVDMRLRPSGASGLLVSSLGAFERYQQNEAWTWEHQALVRARVLVGCKQVGAAFEGVRAKVLGQARDLEKLRGEVSEMRAKMRDNLGTKATAAGTAANAFDAGVPFDIKQDAGGIVDIEFMVQYAALAWSHDHPAILRWTDNIRILEELEQANLMPASDAVLLREVYKAFRSASHRQALQKEAGVIDAAQFADERREVRRIWGELGLS
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: ACCA_CERS4
Sequence: MNYLEFEKPLSEIEGKAEELRALARGNREMDVEKEASALDKKAETLLKDLYKDLTPWRKCQVARHPDRPHCKDYIEGLFTEYTPLAGDRNFADDHAIMGGLARFNDNPVVVIGQEKGHDTKTRIERNFGMARPEGYRKAIRLMEMAHRFRLPVITLVDTPGAYPGKGAEERGQAEAIARATQKCLEIGVPLVAVVIGEGGSGGAVALATANRIAMLEHSVYSVISPEGCASILWKDAEKMREAAEALRLTAQDLHKLGVIDRIIKEPLGGAQRGRRETVDAVGKAIEMMLKELVGRKPEWLVKDRRNKFLDMGSKGLAA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMA_CLAM3
Sequence: MAEPRTLVLLRHGNSDWNQKNLFTGWVDVELSEQGVAEGQRAGELLAESGILPDVLHTSVLIRAIDTANIALKRAGRSWIPVQRTWRLNERHYGALQGKDKAQTLAEYGPEQFATWRRSFDVPPPPIDDDDEYSQSRDPRYADLGDALPRTECLKDVIERMLPYWESDIQPDLASGRTVLVTAHGNSLRALVKHLDGISDADIAELNIPTGIPLVYRLDEDYRPIVPGGEYLDPEAAAAGAAAVAAQGSKK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: KDPA_ECOHS
Sequence: MAAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTTGVERVLFRALGVSDREMNWKQYLCAILGLNMLGLAVLFFMLLGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSMSTLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFLPYQAVNTVEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANSSHPFENPTALTNFVQMLAIFLIPTALCFAFGEVTGDRRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGTDSSINMEGKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGRTPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKSQAASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPEE_OCEIH
Sequence: MLNDKAIRQSKIIYWSSGIVSICGIIFEVLFGALGSYILGDGVKQYTLTISLFLTGMGIGASLSEKFMRNLIIKFVWIEFCVALIGGFSSFIMFGITAFAPAGTDAFYLYSITLIIGALTGVELPILIRKANEIGVTLNKSTARVLFSDYAGGLIGGVLFVFLFRPYFGMVKTAFLVGLINLTVALIVLWLFRKEIRHFIVHAVIGGVIGVLLIAGLFFGEEMAFNFEQKLYQDPIIHMEESSYQKITVTQDEKDIRLYLDGSLQFSSVDEHRYHEVLVHPAMANVETPENVLILGGGDGIAAKEVLKYQDVKQVTLVDLDPAVVELANENRHLLEINEGALMDEKVEVKNMDAFQFLEDTSEWYDVILVDLPDPNNESLNKLYTKEFYSLVRNHLKPEGTLMVQATSPVFAREVYWTISETISSTNLNTENLHVDVPSFGNWGFVMASREEIDLDIMEIPVSTRFLTDDMMPALTAFGKDEDQQIPNFELKANTLIDPHLIQIYEKAWENY
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MOAC_YERE8
Sequence: MTQLTHINAAGEAHMVDVSAKADTVREARAEAFVEMHATTLAMIIEGSHHKGDVFATARIAGIQAAKKTWELIPLCHPLLLTKVEVQLEAQPEHNRVRIESCCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMIIGPIRLLAKSGGKSGDFKVNP
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: GLPK_AROAE
Sequence: MSYLLALDQGTTSSRALVLDRDGQVKGAAQQTFAQHYPQPGWVEHDPAEILATQFDCARTALERAGVAASALAAVGITNQRETTLLWERSTGRALAPAIVWQDRRTAAACDRLREAGHADTIRASTGLEVDAYFSATKLAWLLDHVPGARARARAGELAFGTVDSWLVWHLSGGALHVTDAGNASRTMLFNIHRCEWDETLLALLDIPPALLPRVVDSSGVCGTTCAEVLGAAVPIAGIGGDQQAATFGQACFAPGMAKNTYGTGCFLLMNTGAAPVTSTNRLLTTIGWRSRGETCYALEGSIFIGGALVQWLRDGLGLIRRAEDVEALAASVPDSEGVVLVPAFTGLGAPYWDAYARGTLFGLTRGTGAAHIARAALEAIALQTVDLVAAMDRDGAGPLAELRVDGGAAANDLLMQIQADLLGVPVVRPKMLETTALGAAYLAGLGVGMWSGIEELASHWRAERRFEPVMAEDRREAAIARWRRAVERARGWVAA
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: KDSB_NEIMF
Sequence: MTEFVVLIPARLDSSRLPGKALADIHGKPMVVRVAEQAAKSKAARVVVATDHPDIQTACQAHGIEVVMTSNRHESGTTRLAEASAALKLPPHLVVVNVQGDEPLIAPELIDRTAEVLVENNVQMATAAHELHDFDELMNPNAVKVVLDKNRNAIYFSRAPIPYPRDAMRAGKREMPSETAVLRHIGIYAYRAGFLQRYAEMSVSPLETIESLEQLRVLWHGYPIAVETAKEAPAAGVDTQEDLDRVRAVFQTV
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CIDA_STAEQ
Sequence: MEKAKFVIKLILQLALIMLITFIGTEVQKLLHIPLAGSIVGLMLFFLLLQFKIVPESWINVGADFLLKTMVFFFIPSVVGIMDVASNITMNYILFFIVIIIGTCLVALSSGYIAEKMLEKSNTRKGTDHS
What is the function of this protein?
Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation.  Inhibited by the antiholin-like proteins LrgAB.  In an unstressed cell, the LrgAB products probably inhibit the function of the CidAB proteins.  When a cell is stressed by the addition of antibiotics or by other factors in the environment, the CidAB proteins possibly oligomerize within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability.  These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential.
What are the official names of this protein?
Holin-like protein CidA.
What is the protein family that this protein belongs to?
Belongs to the CidA/LrgA family. CidA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GSTA4_MOUSE
Sequence: MAAKPKLYYFNGRGRMESIRWLLAAAGVEFEEEFLETREQYEKMQKDGHLLFGQVPLVEIDGMMLTQTRAILSYLAAKYNLYGKDLKERVRIDMYADGTQDLMMMIAVAPFKTPKEKEESYDLILSRAKTRYFPVFEKILKDHGEAFLVGNQLSWADIQLLEAILMVEELSAPVLSDFPLLQAFKTRISNIPTIKKFLQPGSQRKPPPDGPYVEVVRTVLKF
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
What are the official names of this protein?
Glutathione S-transferase A4, GST A4-4, GSTA4-4, GST class-alpha member 4, Glutathione S-transferase 5.7, GST 5.7.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Alpha family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: E4PD_KLEP7
Sequence: MTIRIAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGIAHLLKYDTSHGRFAWDVRQEREQLFVGDDSIRLLHEPTIAALPWRELAVDVVLDCTGVYGSREHGEAHLQAGAKKVLFSHPGGNDLDATVVYGVNQDELRAGHRIVSNASCTTNCIIPIIKLLDDAYGIESGTVTTIHSAMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLAAGITRIFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKACEVNQLLQKAAQGAFHGIVDYTELPLVSTDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMAAIGFRFDA
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LFTR_YERE8
Sequence: MRITQLSSQSFAFPSPELALREPNGLLALGGDLSPPRLLAAYERGIFPWFSPGEMILWWSPDPRAVLYPEDLHISRSMRRFLRNCPYRFTLNHAFKDVIRACATLRDEGTWIGDDVQQAYCHLHTLGHAHSVEVWLENELVGGLYGISVGSLFCGESMFSRANNASKSALMVFCHHFTRHGGELIDCQVLNAHTASLGAIEIPRNFFLQQLSQLQFSPLPAECWLPQSLNFSSAMQ
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS2_RHIL3
Sequence: MSGFSLSDLESIVAERSKAPPEQSWTAKLVAGGQPKAAKKLGEEAIEAVMAAVTGDRDNLTYEAADVLYHLLVVLKIAEIPLENVMAELERRTAQSGLKEKASRQSS
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECPE_ECOKI
Sequence: MFRRRGVTLTKALLTVVCMLAAPLTQAISVGNLTFSLPSETDFVSKRVVNNNKSARIYRIAISAIDSPGSSELRTRPVDGELLFAPRQLALQAGESEYFKFYYHGPRDNRERYYRVSFREVPTRNLTKRSPSGGEVSTEPVVVMDTILVVRPRQVQFKWSFDQVTGTVSNTGNTWFKLLIKPGCDSTEEEGDAWYLRPGDVVHQPELRQPGNHYLVYNDKFIKISDSCPAKPPSAD
What is the function of this protein?
Part of the ecpRABCDE operon, which encodes the E. coli common pilus (ECP).  ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition.
What are the official names of this protein?
Probable fimbrial chaperone EcpE, Meningitis associated and temperature regulated protein F.
What is the protein family that this protein belongs to?
Belongs to the EcpB/EcpE family.
Protein: RIMP_CHLT3
Sequence: MMDSRLKLIQDWLLQLLAEMTVSDPDGNEHEVFLVDIEVHSNKTIDIIEVFADTDSGISVENCKFLSKHISAELDASEEMQALLPRHFKLVVSSPGLSRPLTMNRQYKKNIGRLMQVTYQNADGEIKTIDGRFISLEEEAEASITLDITKIQKSKPNAKPKPPELVTIPFSQIQKAIVQVEF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFPL_PSEA6
Sequence: MPKASEVKKNAAIEHNDKVYVVKDINKLTPSGRAGASLYRMRLYEVTTGAKADESFKADEMIKTADFVRQPVTFSYIDGDEYVFMNSEDYTPYNINKETIEEELLFIAEDTTGLQVMIVNGSAVGIELPPNVELVITETDPSIKGASASARTKPATLSTGLTVQVPEYISSGERIKISTSEHKFVSRADK
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: PTH2_BOVIN
Sequence: MISRSLVMEYLTNPGALSLAAGVACGVCLGWGLRMRFGMLPKSSVRETNPDTETEASILGESGEYKMILVVRNDLKMGKGKVAAQCSHAAVSAYKQIQRRNPELLKEWEYCGQPKVVVKAPDEETLVELLTHAKVLGLTVSLIQDAGRTQIAPGSRTVLGIGPGPADLIDKVTGHLKLY
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase 2, mitochondrial, PTH 2, Bcl-2 inhibitor of transcription.
What is the protein family that this protein belongs to?
Belongs to the PTH2 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: T229B_HUMAN
Sequence: MASAEPLTALSRWYLYAIHGYFCEVMFTAAWEFVVNLNWKFPGVTSVWALFIYGTSILIVERMYLRLRGRCPLLLRCLIYTLWTYLWEFTTGFILRQFNACPWDYSQFDFDFMGLITLEYAVPWFCGALIMEQFIIRNTLRLRFDKDAEPGEPSGALALANGHVKTD
What are the official names of this protein?
Transmembrane protein 229B.
What is the protein family that this protein belongs to?
Belongs to the TMEM229 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MSRQ_AZOOP
Sequence: MTFQPTPRQLSAIKAALFLLTLLPALHYAHGLWSDSLGANPIEALTRGMGIWTLNFLFLTLCVSPLRKLSGWHWLLRLRRMLGLTAFAYGCLHLLTYLWLDQFWDVDAIARDIWKRPFITVGATAFLLMLPLALTSSHAAIRSLGGKRWQSLHRAVYAVAILGVVHYLWLVKRVALLDPIIYALVLAILLGWRVVERIRLNGPWPTRSTPPAVQPVVFMKRDAVAALGEPKKR
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain (By similarity).  Probably involved in protection against reactive chlorine species (RCS) generated by chlorite and hypochlorite (PubMed:25968643).
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.