PharMolix/UniProtQA huggingface dataset:
Protein: RL34_MAGSA
Sequence: MKRTYQPSKLVRARRHGFRARMATVGGRKVIANRRRQGRKKLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: CH10_LISW6
Sequence: MLKPLGDRVVIEVLEAEEKTASGIVLPDSAKEKPQSGKIVAVGSGRVLENGTKEPLEVAEGDTVIFAKYSGTEVTYEGTDYLILRESDILAITK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSP4_ROTJ1
Sequence: MEGTSESPVLDEFEVNNNDYDNDFISRFSQNPLNAFSLFTDGNLQEYFMNNSLEKIVIHVVLIVISLCGIKAQTSKIIYVVRLLFWKIYNVINNLVNKVINREKIINHQVVDNRFREFEERFRLLLLQHDKNIAKQDDIVQYNKLDNFAESIKSEFNLKVAEMERRFQELKWRCDMIANKAMNTIVLANTVDSNNKDEKIVFDEGSVVQYNRE
What is the function of this protein?
The secreted form acts as an enterotoxin that causes phospholipase C-dependent elevation of the intracellular calcium concentration in host intestinal mucosa cells.  Increased concentration of intracellular calcium disrupts the cytoskeleton and the tight junctions, raising the paracellular permeability.  Potentiates chloride ion secretion through a calcium ion-dependent signaling pathway, inducing age-dependent diarrhea.  To perform this enterotoxigenic role in vivo, NSP4 is released from infected enterocytes in a soluble form capable of diffusing within the intestinal lumen and interacting with host plasma membrane receptors on neighboring epithelial cells such as integrins ITGA1/ITGB1 and ITGA2/ITGB1.
What are the official names of this protein?
Non-structural glycoprotein 4, NSP4, NCVP5, NS28.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP4 family.
What are the subcellular locations of this protein?
Host rough endoplasmic reticulum membrane; Single-pass type III membrane protein. Host membrane, host caveola; Single-pass type III membrane protein. Secreted. Note=NSP4 localizes also in vesicular structures which contain autophagosomal markers and associate with viroplasms in virus- infected cells. Additionally, a soluble form of glycosylated NSP4 is secreted despite retention of its transmembrane domain.
Protein: UL13_EHV1B
Sequence: MARSRRRSSVDEMDVGGSATSEYENCGGPSFSPLNLSRPKKSTRGRSLRSAQAWGGKQLHPERSTPLARNDCGPSSKPRRRHEVGRSNKGLGASLDRTDEDTSQCPRIRASAIRCGASTRKIVRITGECDAQQGDSRPGRSEMAGWHSPPKRRRTPSRHGNSDNERSHLPRLSSHGVVRVGGRPLTQTPLQKTIILQPKLVRKVFMPTFTVNPEMHYRRVALGEIPKFGGAGSYGEVQIFKQTGLAIKTASSRSCFEHELAVSLLTGECSLRAQASLGIGGIICLMAFSLPSKQMVFPAYDADLNAYGYRLSRSGPPSVLVTESIERAFIGLGRALVYLNTSCGLTHLDVKGGNIFVNHSHFVISDCVIGDLSLMTLNTNSMAMRAEFEIDTGEEEIKTLRLPRSASQMTFSFVIGHGLNQPISVIADFINNSGLAKSTGPIKHDVGLTIDLYALGQALLELLLVGCISPCLSVPILRTATYYYYSNKLSVDYALDLLAYRCSLYPALFPTTPLTTIYGIPWDQVEGVFESIAGAHHREAFRAHLERYRLTHRRLFASIRIPSAFTGVLELVSLLCHANEKARLSIPLLWTPRP
What is the function of this protein?
Multifunctional serine/threonine kinase that plays a role in several processes including egress of virus particles from the nucleus, modulation of the actin cytoskeleton and regulation of viral and cellular gene expression.  Regulates the nuclear localization of viral envelopment factors UL34 and UL31 homologs, by phosphorylating the US3 kinase homolog, indicating a role in nuclear egress.  Disrupts host nuclear lamins, including LMNA and LMNB1.  Phosphorylates the viral Fc receptor composed of glycoproteins E (gE) and I (gI).  Phosphorylation of glycoprotein E (gE) by UL13 homolog alters its subcellular localization, from the host early endosome to the plasma membrane.  Participates in the transcriptional regulation of cellular and viral mRNAs mainly by phosphorylating the viral transcriptional regulator ICP22 homolog (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase UL13 homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus.
Protein: RWA4_ARATH
Sequence: MVVSQPITPGQVSFLLGVIPLMIAWLYSEFLEYRRSSFHAKVHSDKNLVELEMVTNKEDEGTVLMEGGLPRSASSKFYSSPIKTNLIRFLTLEDSFLLENRATLRAMAEFGAILLYFYICDRTSLIGQSQKNYSRDLFLFLFCLLIIVSAMTSLKKHTDKSPITGKSILYLNRHQTEEWKGWMQVLFLMYHYFAAVEFYNAIRVFIAGYVWMTGFGNFSYYYIRKDFSLARFTQMMWRLNFFVAFCCIILNNDYMLYYICPMHTLFTLMVYGALGIYSQYNEIASVMALKIASCFLVVILMWEIPGVFEIFWSPLAFLLGYTDPAKPDLPRLHEWHFRSGLDRYIWIIGMIYAYFHPTVERWMEKLEECDAKRRMSIKTSIIGISSFAGYLWYEYIYKLDKVTYNKYHPYTSWIPITVYICLRNCTQQLRRFSLTLFAWLGKITLETYISQFHIWLRSSVPNGQPKLLLSIIPEYPMLNFMLTTAIYVLVSVRLFELTNTLKSVFIPTKDDKRLLHNVIAMAAISFCLYIIGLILLLIPH
What is the function of this protein?
Probable O-acetyltransferase involved in the acetylation of xylan during secondary wall biosynthesis.
What are the official names of this protein?
Protein REDUCED WALL ACETYLATION 4.
What is the protein family that this protein belongs to?
Belongs to the PC-esterase family. CASD1 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: DING_STAHJ
Sequence: MGHTSYAVVDLETTGNQLDYDEIIQIGITFVSNNKISGTYHSMIRTDLDIPPFIQALTSIEDTMLEQAPYFHEIAQEIYKQLKDRVFVAHNVDFDLNFIKKAFQNCNIDFKPKKVLDTLELFKIAYPTDKSYQLSELAEAHDIPLDNAHRADEDATTTALLMIKAFQKFEQLPIDTLKQLYYLSKNLKYDLFNVLFEMVRQHENSPLDNQYGQFEQIIYKKQIDLKAPKTSFNGSLKDLYSEVVKSLNLTYRPQQLYLSEIILEQLMHNDKAMIEAPLGSGKSLAYLLAALMYNIETGRHVMISTNTKLLQNQLLLKDIPSINQALNFKINATLIKSKSEYISLGLISQILKDETTNYEVNILKMQLLTWIIETETGDIQDLNLKGGQKMYFDQKIETYVPVRHDMHYYNYIKRNAHHIQIGITNHAHLIHSDQENSIYQLFDDCIIDEAHRLPDYALNQVTNDLDYSDLKYQLGLIGKNENEKLLKAIDKLEQQRILERLDIAPIDVFGLKMNISEIHDLNERLFNHIFEIIQNSDVYDDDIHRHHYVFEFDSTQILKDLHLIVDKINKTLEIFNGMTHKTIKTLRKQLLYINDTYRNIEQSLKDKHTAYLSIRNLTQKSTIKLIVKDYAVRDILTTRVLDKFNSLTFISGTLTFNHKFDAFKNWFKEDVHFNTYQVPSTLSNHANTNVYIPSDVSSYNFKNIDDYVASIVDYIQEYVTITDSKCLVLFTSYRMMHMVQELLNELPTFEDYVVLTQQQNQNYKIVQQFNNFDKTILLGTSTFFEGFDYQAKGIKCVMIAKLPFMNKYNTKHWLMDSEFDSTFKDYVLPDAVTRFRQGLGRLIRNEDDQGLIVSFDDRLVSSNYKNFFAQTLENYKQKKGDIKQFSKLVNKIQHNIDANK
What is the function of this protein?
3'-5' exonuclease.
What are the official names of this protein?
3'-5' exonuclease DinG.
What is the protein family that this protein belongs to?
Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.
Protein: SYL_PROMP
Sequence: MITSENTDNRATNLYKPSDIEGKWQKIWEDDNLYNTDEQASNKEKFYALSMFPYPSGNLHMGHVRNYVITDLIARFQRFQGKVVLHPMGWDAFGLPAENAAIERGINPDKWTKQNIAHMKSQLKLLGLSVDWDREFATCDENYYVWTQFLFLELHKAGLVYQKESEVNWDPIDNTVLANEQVDSEGKSWRSGAIVEKKLLTQWFLKITDYAEELLQDLEKLNEWPERVKIMQENWIGKSIGTNINFKIKEFKKEKIQVFTTRPDTLFGVTYLAISVNHPLIKKISDNKILSKLENLKIYLQESKDKDQKKIGIPTNLIAINPINSKEIPILIASYVLDEYGTGAVMGVPAHDERDFEFAKINSIDIKQVIIKEKDKITSQLTNAFTDNGFLINSNNFDGLNNSDAKKHISEHGERNGWAENKIQFRLRDWLISRQRYWGCPIPIIKCTNCGSVPVNKKDIPVRLPNEIKISSNKINSLGSNQSWINTTCPKCGNLASRETDTMDTFMCSSWYFLRYPSSKSLTKPFEKEKINKWLPVDQYVGGVEHAILHLLYARFLTKALRDNNLFDIDEPFKRLLTQGMVQSAAYKNSITGKYISPTDIKDITNPKDPKDNSKLEVLFEKMSKSKYNGIDPESVIKKYGADTARMFILFKAPPEKDLEWGDSDVEGQYRFLCRIWKLFLDYSNNDITHEADKLKKENESSLLKSINIAIKEISNDIKNNQFNTAISELMKFYNSISSNLNYVNKDLRRESLMKFCILLAPFAPHISDEIWHLIGNSKSVHLEKWPVFDEDALKENSFELVIQINGKVRDKINVEINISDDEIKEKTLIRPNVKKWIDNKTIRKIIIVKGRIINIVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UXUA_ENT38
Sequence: MEQTWRWYGPNDPVSLDDVRQAGATGVVTALHHIPNGEVWPVEEIKKRQAVLADKGLTWSVVESIPVHEDIKTHSGQFETWIANYQQSIRNLATCGIDTVCYNFMPILDWTRTDLEYQMPDGSRALRFDQIAFAAFELHILKRPSAEADYSAEEQQQALKWFEDASDADIEKLTRNIIAGLPGAEEGYTLDQFRARLAEYGDIDKNQLRENMAYFLRAIVPVAEACGLRLAVHPDDPPRPILGLPRIVSTIEDMQWLKETVDSINNGFTMCTGSYGVREDNDLVKMIEAFGDRIHFTHLRATCRENNPKTFHEAAHLGGDVNMVAVVDAILSEEQRRKHAGDMRPIPFRPDHGHQMLDDLRKKTNPGYSAIGRLKGMAEVRGVELALKMLKYPELL
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: YOPH_BACSU
Sequence: MSDQNEKSPSWVGDIIKLSPKYLLGLAVFSGIGLWLGNVGLGKTLGIKDAINSYKLYLGLVFLASTSFILSHFIWWISLGIKNKIDQKYSYKLQKERLRNLNRREKQILSPYIFDDVRSVELSITDGTAQELEHLKIIYRSSNISNRGSYFAYNIQPWARGYLTKNKHLLHESIDHIL
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YopH.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYH_METHJ
Sequence: MIQKPRGTRDMLPDEMERRREIEARMRARARLYGFREIATPVFEELELFTIRSGEGIINEMYVFEDKGGRSLALRPELTAPVLRMYVEEGRSLNKPVKWCYFADCFRYERPQKGRYRQFWQFGAELIGADSAMGDAEVITLGYDLLRTAGVTFVLRIGHLSFMRTLLADLADGDKKKIRAFLDKREEEAAITYLRDIGRDDLCDPLIRLCGARTLEDVFAIIGEIPEAARVREMFAILDASGIPYEINPAIARGLDYYTGVVFECFAEGLGAENQILGGGAYRLAHLFGGEDTPSAGFAIGFDRVMVALGEASWVPWQPQVMIITTNEGRDYALTIAGQFRMNGIITETDLMDRSFSAQMKAAGKSADYAVIIGKDEVETGTITLKDLKAGTQEKITADEAIQKLTSA
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_MICLC
Sequence: MTEQTPAVSEERGYRKALRGIVVSDKMDKTIVVEVQDRKKHSLYGKVMKTSKRVKAHDEENTAGVGDRVRIAETRPLSASKRWRLVEVVERAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: Y1638_XYLF2
Sequence: MLLHIPTILSRTHATSMQERLAAANWTDGRETVGPQGAQVKHNLQLPETSPLRQELGQEILDALARSPLYFAATLPLRTLPPRFNRYQENHQYGFHVDGAVMSLPVAPDHTPASLRSDISCTLFLNDPDEYEGGELIIADTYGEHEVKLPAGDLIIYPSTSLHRVAPVTRGMRIASFFWVQSLVRQATHRHQLLELDTAIQSLTASNTDHNTILRLTNVYHNLLREWSET
What are the official names of this protein?
PKHD-type hydroxylase XfasM23_1638.
Protein: ATPG_SCHPO
Sequence: MLRQTLTQASRMRPCISVVGFRGFHASSPCEATLKEIEQRLKSIKNIEKITKTIKTVAQTKLTRAQRAMEASNKYYRVSDEVFKEAGTKAPEEGKTLMVACSSDKGLCGGIHSSISRLIRRELHDPKTFENTSLCILGEKVRTQLLRFCPESFYLTFAHIGGASPSFEEALQISSNILEHAKDYDRIVLVYNKFASAVSFETVMKNLYTTKAINESPNLSAYEVSDEVHQPLMEFAFANAIFSAMAEAHCSEMSSRRNAMENASKSAGDMINKFSIQYNRQRQASITNELIDIVTGANSLA
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(1) domain and the central stalk which is part of the complex rotary element.  The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3).  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
What are the official names of this protein?
ATP synthase subunit gamma, mitochondrial, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane; Peripheral membrane protein.
Protein: DAPE_SPHAL
Sequence: MTRNIDPIELAKALIAVPSVTPATGAVFDVLEAALTPLGFTVERFIDGIEPDGPVENLLAVRRGSGPKHFGFAGHLDVVPPGVGWTSDAFAPEIRGELLYGRGAVDMKGAIAAFVAAAAATPVDAGTISLIITGDEEGPAIFGTRALMEHMDARRVTPDMIVVGEPTSVNRLGDMVKIGRRGSVNIWIDVPGTQGHVAYPHLADNPIPKLVKILAAIDAVVLDEGSDWFQPSNIEFTDIEVGNGATNVIPASARARLSIRFNDQHRGAELVAMIERIAHEVEPAARVLGKISGEAFLTPPGELSELVAEAIHAETDICAEMSTTGGTSDARFLHALCPVVEFGLTNATMHKLDEAVAIEDLHRLTAIYRGILMRVFL
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: MEDAG_MOUSE
Sequence: MATAACEPVARPSLTSISSGELRSLWTCDCELALLPLSQLLRLQPGAFQLRGEQLLVPGPGEPAAARGGFNVFGDGLVRLEGQLYRLSSYIKRYVELTNYCDYKDYRETILSKPMVFFINVQTKKDISKERTYAFLVNTRHPKIRRQIEQGMDMVISSVIGESYRLQFDFQEVVKNFFPPGTIVLNGENLSFTYEFKADALFDFFYWFGLSNSTVKVHGKVLNLTSTNPEKKETIKLFLEKMSEPLIRRSSFSDRKFSVTSRGSIDDVFNCNLSPRSSVTEPLLAEFSFPSLLECEETSSQLI
What is the function of this protein?
Involved in processes that promote adipocyte differentiation, lipid accumulation, and glucose uptake in mature adipocytes.
What are the official names of this protein?
Mesenteric estrogen-dependent adipogenesis protein, Activated in W/Wv mouse stomach 3, mAWMS3, Mesenteric estrogen-dependent adipose 4, MEDA-4.
Protein: PYRI_SALA4
Sequence: MTHDNKLQVEAIKCGTVIDHIPAQVGFKLLSLFKLTETDQRITIGLNLPSGEMGRKDLIKIENTFLTEEQVNQLALYAPQATVNRIDNYDVVGKSRPSLPERINNVLVCPNSNCISHAEPVSSSFAVKKRANDIALKCKYCEKEFSHYVVLAN
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: PP2A_CAEEL
Sequence: MAAAPPSADPLDKALIVDVDQWIEQLYECKPLSENQVKTLCEKAKEILEKEPNVQEVRCPVTVCGDVHGQFHDLMELFKMGGKSPDTNYLFMGDYVDRGYYSVETVSLLVCLKIRYKDRVTLLRGNHESRQITQVYGFYDECLRKYGNSNVWKYFTDLFDCFPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHSNGLTLISRAHQLVMEGYNWSHDRNVVTVFSAPNYCYRCGNQAAMVELDDDLKYSFLQFDPAPRRGEPHVTRRTPDYFL
What is the function of this protein?
Protein phosphatase which plays an essential role in early embryonic cell division (PubMed:20392746, PubMed:17218259, PubMed:21497766).  Probably together with constant regulatory subunit paa-1 and regulatory subunit sur-6, positively regulates centriole duplication by preventing the degradation of sas-5 and kinase zyg-1 (PubMed:21497766).  In addition, plays a role in the recruitment of sas-6 and maybe sas-5 to centrioles and may dephosphorylate sas-5 and zyg-1 negative regulator szy-20 (PubMed:21497766).  During vulva development, may play a role with regulatory subunits paa-1 and sur-6 in the induction of vulva cell precursors by positively regulating let-60/Ras-MAP kinase signaling, probably by promoting lin-45 activation (PubMed:10521400).  In association with regulatory subunit rsa-1 and probably paa-1, regulates microtubule outgrowth from centrosomes and mitotic spindle assembly ensuring the stability of kinetochore microtubules (PubMed:17218259).  Plays a negative role in axon guidance probably by dephosphorylating unc-51, unc-14 and vab-8 (PubMed:20392746).
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A catalytic subunit, PP2A.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-1 subfamily.
What are the subcellular locations of this protein?
Perikaryon. Cell projection, axon. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Note=Localizes to the margins of VD neuron growth cones and to small transport vesicles (PubMed:20392746). During mitosis, localizes around chromatin after the nuclear envelope breakdown (PubMed:17218259).
Protein: PYRD_CORGB
Sequence: MSKQSPTRKLRQTVYDASLKVMFTLRPERIHGLMNKALGVVDGVAPLNRTMEKIIAVHDDSLSQEVFGVTFPRPLGLAAGFDKNASMADAWGAVGFGYAELGTVTASPQPGNPTPRLFRLPADKAILNRMGFNNLGAAEVATNLSNRKSTDVIGINIGKTKVVPAEHAVDDYRRSASLLGDLADYLVVNVSSPNTPGLRDLQAVESLRPILAAVQESTTVPVLVKIAPDLSDEDIDAVADLAVELKLAGIVATNTTISREGLNTPAGEVEAMGAGGISGAPVAARSLEVLKRLYARVGKEMVLISVGGISTPEQAWERITSGATLLQGYTPFIYGGPDWIRDIHLGIAKQLKAHGLRNIADAVGSELEWKN
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y3534_MYCMM
Sequence: MPRTDNDSWDLATSVGATATMVAAARAIATNADNPLIADRFAEPLVRAVGVDFFTRWVTGDLVVADVDDTESGWQLAQMPDAMAVRTRFFDAFFQDATRAGVRQAVILASGLDARAYRLDWPAGMTVFEIDQPEVIAFKTTTLAGLGAVPRADLRTVAVDLRQDWPKALTDAGFDAGSPTAWIAEGLFGYLPPEAQDRLLDNITALSAAGSRLACEAIPNRPQQDAEKARELMRKATARWREHGFELEFGDLGYEGDRADVALYLQDLGWQSVGTQMGQLLADNGAAPIPHNDDSVTMADTIYYSSVLTA
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MMAR_3534.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: R1AB_CVPR8
Sequence: ITEFSWNKYLYELIQRFEYWTVFCTSVNTSSSEGFLIGVNYLGPYCDKAIVDGNIMHANYIFWRNSTIMALSHNSVLDTPKFKCRCNNALIVNLKEKELNEMVIGLLRKGKLLIRNNGKLLNFGNHFINTP
What is the function of this protein?
The replicase polyprotein of coronaviruses is a multifunctional protein: it contains the activities necessary for the transcription of negative stranded RNA, leader RNA, subgenomic mRNAs and progeny virion RNA as well as proteinases responsible for the cleavage of the polyprotein into functional products.
What are the official names of this protein?
Replicase polyprotein 1ab, pp1ab, ORF1ab polyprotein.
Protein: RIR1_MYCGE
Sequence: MTSKEKIPTFNTEEDVESYISFNAQAKIYDDFAIDLQAVESYIQEHVKPKTKVFHSTKERLDFLIKNDYYDEKIINMYSFEQFEEITHKAYSYRFRYANFMGAFKFYNAYALKTFDGKYYLENYEDRVVMNVLMLANGNFNKALKLLKQIILNRFQPATPTFLNAGRKKRGEFVSCYLLRIEDNMESIGRAITTTLQLSKRDGGVALLLSNLREAGAPIKKIENQSSGIIPIMKLLEDSFSYSNQLGQRQGAGAVYLHCHHPDVMQFLDTKRENADEKIRIKSLSLGLVIPDITFQLAKNNEMMALFSPYDIYQEYGKALSDISVTEMYYELLENQRIKKTFISARKFFQTIAELHFESGYPYILFDDTVNRRNAHKNRIVMSNLCSEIVQPSLPSEFYSDLTFKKVGSDISCNLGSLNIARAMESGSELAELIQLAIESLDLVSRISSLETAPSIKKGNSENHALGLGAMNLHGFLATNAIYYDSKEAVDFTNIFFYTVAYHAFSASNKLALELGKFKDFENTKFADGSYFDKYTKVASDFWTCKTEKVQALFDKYQVKIPTQENWKQLVASIQKDGLANSHLMAIAPTGSISYLSSCTPSLQPVVSPVEVRKEGKLGRIYVPAYKLDNDNYQYFKDGAYELGFEPIINIVAAAQQHVDQAISLTLFMTDKATTRDLNKAYIYAFKKGCSSIYYVRVRQDVLKDSEDHTIKIKDCEVCSI
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
What are the official names of this protein?
Ribonucleoside-diphosphate reductase subunit alpha, Ribonucleotide reductase.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase large chain family.
Protein: MDCB_PSEA7
Sequence: MNAIANLAATPRADLGECLADLAVDALIDEAELSPKPALVDRRGNGAHADLHLGLMQASALSLWPCFKEMADAAQRHARIDARLRGVLGQLGREGEVAMLRTTEGVNSHRGAIWALGLLVAAAALAPRRTQAGEVAARAGRIALLDDPAAASGDSHGERVRRRYGVGGAREEARLGFPRAVRHGLPQLWRSRESGAGEQNARLDALLAIMSVLDDTCVLHRAGRVGLAAMQEGARAVLAAGGSASLAGRRRLRELDRRLLALNASPGGAADLLAACLFLDRLPAALGGWAGSL
What is the function of this protein?
Involved in the formation of 2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase.
What are the official names of this protein?
Probable 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase, 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the CitG/MdcB family.
Protein: EPHX3_XENTR
Sequence: MQLYLSRLLLIVTRTALRVTGVFFWVLVYVAALLAAVSYIPDALRLLTRGPLSAFRWGPRKAAPACLTSSAHGQHGYIRMKDSGIRFHYVASGDKRNPLMLLLHGFPENWYSWRYQLDEFSNGYRTVAIDLRGFGGSDAPSRLEDYKMEILLQDLQDLIRGLGYSRCVLVGHDWGGTLAWTFAVRHRDMVTHLIVMNAPHPSAFHDYVLSHPSQLFSSRYVFLFQLPLIPEILLSLRDFEHIKKPLTDATHGIQNVECKLSKEEVEAFVYYPSQKGALTPPLNYYRNLFGFFPVKAQDVLVPTLLLWGEHDAFLEAAMVPEMQQYVRAPFRAEIIPNASHWLQQDRPQEVNKIIRDFLKEDFLVHRN
What is the function of this protein?
Catalyzes the hydrolysis of epoxide-containing fatty acids.  Active in vitro against epoxyeicosatrienoic acids (EETs) including 8,9-EET, 9,10-EET, 11,12-EET and 14,15-EET and leukotoxin.
What are the official names of this protein?
Epoxide hydrolase 3, EH3, Abhydrolase domain-containing protein 9.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein.
Protein: RSGA_CLOBJ
Sequence: MKGTIIKGIGGFYYIKIDNSEEIIECKARGKFRHTELTPMIGDYVEISIDKNNKGAIEKIYERRSELFRPAVANVTQALVVFSFKNPDINIDLLNKFLLLCEYNNLKAIVCFNKMDLVNKEDYKDIISMIEQAGYDIIFLNAKEERNMDIIKKLIKDNVTVFCGPSGVGKSTMLNKIIGKETMITGNISEKLKRGKHTTRHSELIYVDEGLLVDTPGFSSLDINFMEKEDLLHCIPEFRDFIGECKFTGCLHHREPNCAVKKAVEEGHIHKNRYDFYIKTLEEFMNRRKKKW
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGT_SALHS
Sequence: MTSSYLHFPDFDPVIFSIGPVALHWYGLMYLVGFVFAMWLAVRRANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPLFLDNPLYLFRVWDGGMSFHGGLIGVILVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPDFRFAMLFPGSRAEDIALLPSHPQWQPIFDTYGVLPRHPSQLYELALEGVVLFIILNLFIRKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIIAGAIMMVWAYRRRPQQHVS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RLA0_DANRE
Sequence: MPREDRATWKSNYFLKIIQLLDDFPKCFIVGADNVGSKQMQTIRLSLRGKAVVLMGKNTMMRKAIRGHLENNPALERLLPHIRGNVGFVFTKEDLTEVRDLLLANKVPAAARAGAIAPCEVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKPGDKVGASEATLLNMLNMLNISPFSYGLIIQQVYDNGSVYSPEVLDITEDALHKRFLKGVRNIASVCLQIGYPTLASIPHTIINGYKRVLAVTVETDYTFPLAEKVKAYLADPTAFAVAAPVAAATEQKSAAPAAKEEAPKEDSEESDEDMGFGLFD
What is the function of this protein?
Ribosomal protein P0 is the functional equivalent of E. coli protein L10.
What are the official names of this protein?
60S acidic ribosomal protein P0, 60S ribosomal protein L10E.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.