PharMolix/UniProtQA huggingface dataset:
Protein: SPE_DROME
Sequence: MASTERNFLLLSLVVSALSGLVHRSDAAEISFGSCTPQQSDERGQCVHITSCPYLANLLMVEPKTPAQRILLSKSQCGLDNRVEGLVNRILVCCPQSMRGNIMDSEPTPSTRDALQQGDVLPGNDVCGFLFADRIFGGTNTTLWEFPWMVLLQYKKLFSETYTFNCGGALLNSRYVLTAGHCLASRELDKSGAVLHSVRLGEWDTRTDPDCTTQMNGQRICAPKHIDIEVEKGIIHEMYAPNSVDQRNDIALVRLKRIVSYTDYVRPICLPTDGLVQNNFVDYGMDVAGWGLTENMQPSAIKLKITVNVWNLTSCQEKYSSFKVKLDDSQMCAGGQLGVDTCGGDSGGPLMVPISTGGRDVFYIAGVTSYGTKPCGLKGWPGVYTRTGAFIDWIKQKLEP
What is the function of this protein?
Endopeptidase which plays a key role in innate immunity by cleaving Tl ligand spz and thereby activating the Toll pathway in response to fungal and Gram-positive bacterial infections (PubMed:16631589, PubMed:16399077, PubMed:18724373, PubMed:26843333, PubMed:16996061).  Acts downstream of pathogen recognition receptors PGRP-SA and GNBP1 and protease grass in response to Gram-positive bacterial infection (PubMed:16399077).  Acts downstream of protease psh in response to fungal infection (PubMed:16399077).
What are the official names of this protein?
Spaetzle-processing enzyme, Spatzle-processing enzyme.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. CLIP subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Probably secreted in the hemolymph.
Protein: LIPB_PARVE
Sequence: HAVGRGGQYTYHGPGQRLVYVMLDLNRRGRDVRAFVKALESWVIDALAEFNLKGEIRDGRVGVWIARPDKASLPDGSMREDKIAAIGVKLRRWVSFHGISINVEPDLGHYAGIVPCGIQGHGVTSLVDMGLPVGMGDLDLALRRSFARNFPPLGG
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity).
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTPA2_GIBZE
Sequence: MTSQAPPQPASSPGVAAPAAASSIPNLKDRLPKLEPRKRRSGPSNPTPIPETPALPTPPDTSSNWTFKTPSRRILSKKDHDIFLSSPTCKLVTAWVFGLAESIVDTPNSAIRDADLSALIKTILHILDETEQLVTKSPPNEQGGSRFGNKAFRGLLDLAQKNSAAWHHDIGVQNEDAINELSTYFCESFGNANRIDYGSGHELNFMIWLLCLYQLGLLKQSDFKPIVLRVFVRYLEVMRVIQMTYYLEPAGSHGVWGLDDYQFLPFLFGATQLLHHPYITPRAIHQDLTLEEFGHEYMYLGQVSFVNSTKTVKGLRWHSPMLDDISSARSWTKIDGGMRRMFVAEVLGKLPVMQHFLFGSLVPADDSMSEDTGAGDEADVEDDPHAGHDHTGKAHDGTGWGDCCGIKVPSSIAAAQEMKKRGMNQGLRRIPFD
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase.  Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A activator 2, Peptidyl-prolyl cis-trans isomerase PTPA-2, PPIase PTPA-2, Rotamase PTPA-2, Phosphotyrosyl phosphatase activator 2.
What is the protein family that this protein belongs to?
Belongs to the PTPA-type PPIase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: USP_DROME
Sequence: MDNCDQDASFRLSHIKEEVKPDISQLNDSNNSSFSPKAESPVPFMQAMSMVHVLPGSNSASSNNNSAGDAQMAQAPNSAGGSAAAAVQQQYPPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFKRTVRKDLTYACRENRNCIIDKRQRNRCQYCRYQKCLTCGMKREAVQEERQRGARNAAGRLSASGGGSSGPGSVGGSSSQGGGGGGGVSGGMGSGNGSDDFMTNSVSRDFSIERIIEAEQRAETQCGDRALTFLRVGPYSTVQPDYKGAVSALCQVVNKQLFQMVEYARMMPHFAQVPLDDQVILLKAAWIELLIANVAWCSIVSLDDGGAGGGGGGLGHDGSFERRSPGLQPQQLFLNQSFSYHRNSAIKAGVSAIFDRILSELSVKMKRLNLDRRELSCLKAIILYNPDIRGIKSRAEIEMCREKVYACLDEHCRLEHPGDDGRFAQLLLRLPALRSISLKCQDHLFLFRITSDRPLEELFLEQLEAPPPPGLAMKLE
What is the function of this protein?
Receptor for ecdysone.  May be an important modulator of insect metamorphosis.  Plays an important part in embryonic and post-embryonic development.  Binds to ecdysone response elements (ECRES) such as in the promoter region of s15 chorion gene.
What are the official names of this protein?
Protein ultraspiracle, Chorion factor 1, Nuclear receptor subfamily 2 group B member 4, XR2C.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSBL_ORYSJ
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: DNAC_ECOL6
Sequence: MKNVGDLMQRLQKMMPAHIKPAFKTGEELLAWQKEQGAIRSAALERENRAMKMQRTFNRSGIRPLHQNCSFENYRVECEGQMNALSKARQYVEEFDGNIASFIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFRNSGTSEEQLLNDLSNVDLLVIDEIGVQTESKYEKVIINQIVDRRSSSKRPTGMLTNSNMEEMTKLLGERVMDRMRLGNSLWVIFNWDSYRSRVTGKEY
What is the function of this protein?
This protein is required for chromosomal replication.  It forms, in concert with DnaB protein and other prepriming proteins DnaT, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' (By similarity).
What are the official names of this protein?
DNA replication protein DnaC.
What is the protein family that this protein belongs to?
Belongs to the DnaC family.
Protein: G3P_CRYNB
Sequence: MVVKVGINGFGRIGRIVLRNAIEHGDLEVVAVNDPFIDLDYMVYMFKYDSTHGRFKGSVEVKDGKLYINNKAIAVFGEKDPANIKWGEAGAEYVVESTGVFTTTEKAGVHLKGGAKKVVISAPSADAPMFVCGVNLDAYKPEYQIVSNASCTTNCLAPLAKVIHDNFTIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGAAANIIPSSTGAAKAVGKVIPSLNGKLTGMSFRVPTSDVSVVDLVCRIEKGASYEEIKNVIKKASESPELKGILGYTEDAVVSTDFIGSTESSIFDAQAGIALNANFVKLVSWYDNEYGYSRRVCDLISYIAGVDAKAQ
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCM7_MOUSE
Sequence: MALKDYAIEKEKVKKFLQEFYYENELGKKQFKYGTQLVHLAHREQVALYVDLDDIAEDDPELVDSICENAKRYSRLFGDVVQELLPEYKEKEVVNKDVLDVYIEHRLMMEQRSRDPGAVRNPQNQYPSELMRRFELYFRGPSSSKPRVIREVRADSVGKLLTVRGIVTRVSEVKPRMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFVKFQEMKIQEHSDQVPVGNIPRSITVVLEGENTRIAQPGDHVSVTGIFLPVLRTGFQQMAQGLLSETYLEAHWIVKMTKSDDDVSGAGELSSEELKQIAEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQSPQGMKIRGNIHICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNVQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPAQFEPLDMKLMRRYIAMCHERQPTVPESLADYITAAYVEMRREARASKDATYTSARTLLAILRLSTALARLRMVDIVEKEDVNEAIRLMEMSKDSLLGEKGQTARTQRPADVIFATIRELVSRGRSVHFSEAEQRCISRGFTPAQFQAALDEYEELNVWQVNTSRTRITFV
What is the function of this protein?
Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells.  Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.  The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit.  The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity).  Uncomplexed form does not show ATPase or DNA helicase (PubMed:12207017).  Required for S-phase checkpoint activation upon UV-induced damage (By similarity).
What are the official names of this protein?
DNA replication licensing factor MCM7, CDC47 homolog.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associated with chromatin before the formation of nuclei and detaches from it as DNA replication progresses.
Protein: MUKF_SALTI
Sequence: MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAVATLNGERLDGEMSEGELVDAFRHVSDAFEQTSETIGVRANNAINDMVRQRLLNRFTSEQAEGNAIYRLTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAAEGGDEFHWHRNVYAPLKYSVAEIFDSIDLTQRIMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLRELQDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIGYDRHVHKFIRTAIDMDKNRIFAQRLRQSVQTYFDDPWALTYANADRLLDMRDEEMALRDDEVTGELPPDLEYEEFNEIREQLAAIIEEQLAIYKTRQTPLDLGLVVREYLAQYPRARHFDVARIVIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Not required for mini-F plasmid partitioning.  Probably acts via its interaction with MukB and MukE.  Overexpression results in anucleate cells.  It has a calcium binding activity.
What are the official names of this protein?
Chromosome partition protein MukF.
What is the protein family that this protein belongs to?
Belongs to the MukF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: CYB_MYODA
Sequence: MTNIRKSHPLMKIINSSFIDLPAPSNISSWWNFGSLLGICLALQIMTGLFLAMHYTSDTATAFNSVTHICRDVNYGWILRYLHANGASMFFICLYLHVGRGLYYGSYLYTETWNVGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFLLPFIIAAMVMVHLLFLHETGSNNPMGIPSDTDMIPFHPYYTIKDILGLLLMIMALLLLVLFSPDMLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALIFSILILIIIPLLHTSKQRSMAFRPLSQCLYWLLVADLLALTWIGGQPVEHPFVIIGQLASILYFSIIIILMPLTSLAENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CLPX_COXBN
Sequence: MSSDEKLQILYCSFCGKSQHQVRKLIAGPAVFVCNECVDLCNDIIREEEIAQAGGAQKKLPTPPEIHRMLDEYVIGQEFAKKVLSVAVYNHYKRLGNQTKKDSVEISKSNILLIGPTGSGKTLLAQTLAKILDVPFAIADATTLTEAGYVGEDVENIIQKLLQKCNYDVEKAKTGIIYIDEIDKIARKTDSPSLTRDVSGEGVQQALLKLIEGTVASIPPQGGRKHPQQEYLQVDTSNILFICGGAFADLHKIIQRRTDKIGIGFAAEVRPKEDFSREASKLIKQTEPGDLIKYGLIPEFVGRLPIITTLEELDEDALMRILTEPKNALVKQYRKLFEFEGVEIDFREDALKAIAKRAIQQKTGARGLRSIVEHTLLDLMYDLPGVAAGLRKVVIDSGVIDQASPPIFIYHHEKASRKVAQE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: PSBL_STAPU
Sequence: MTTPNPNKQGAELSRTGLYWGLLLIFVLAVLFSSYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: YIHY_ECOSE
Sequence: MLKTIQDKARHRTRPLWAWLKLLWQRIDEDNMTTLAGNLAYVSLLSLVPLVAVVFALFAAFPMFSDVSIQLRHFIFANFLPATGDVIQRYIEQFVANSNKMTAVGACGLIVTALLLMYSIDSALNTIWRSKRARPKIYSFAVYWMILTLGPLLAGASLAISSYLLSLRWASDLNTVIDNVLRIFPLLLSWISFWLLYSIVPTIRVPNRDAIVGAFVAALLFEAGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYRKLKQAAEQEEDDEP
What are the official names of this protein?
UPF0761 membrane protein YihY.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL24_ALTMD
Sequence: MANKIRRDDEVVVLAGKDKGKQGKVLRVLIADNRVIVEGVNLVKKHTKPNPQLGVAGGIVEKEASIHVSNVAIVNPATGKADRVGFRFEDEKKVRFFKSNGELV
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RSMG_ACIBS
Sequence: MHPFFQELQQGSQKLGLSLSDEALTLLLKYQDALVLWNKAYNLTAIRDPKEMLVKHLLDSLSILKDLPAGRLLDVGTGGGMPGMIIALCQPERSCVLLDSNGKKIRFLKQFIADLKLKNVIAVQTRVENQDTIDELGQFDVITSRAFASLTDFVGAARPYLHEQSIIAAMKGLIPVEEMEELKQEFSCKVIELHVPRLDEQRHLLLLQRI
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPF2_GLOHY
Sequence: CSYPSKLCNNHRANVNQQRMQQKLIRQQMVER
What are the official names of this protein?
Secreted protein F2.
What are the subcellular locations of this protein?
Secreted.
Protein: ECS1_ARTAN
Sequence: MSLIVEDVIRPNANFPSEIWGDQFLAYDQDEQEGVEQVIKDLKEEVKSELLTALNSPTQHTELLKFIDAIERLGIAYYFEEEINQVFQHMYTAYGDKWTGGNTSLWFRLMRQHGFFVSSDIFSTYKDKEGRFKESLEKDVHGLLELYEAAYMFVPGEGILDDALVFTRTCLDEIAKNPSLSNSAVSSQIREALTQPLHKRLPRLEALRYIPFYQQQASHSETLLKLAKLGFNQLQSLHKKELSIISKWWKSFDVANNLPYARNRPVECYFWALAVYFEPQYSESRVFLSRFFSIQTFLDDTYDAYGTYEELEQFTEAIQRWSITCLDGLPESMKLIFQMLVKIFEEIEEILSKDGKQHHVNYIKETLKEAVQSYMTEARWAKEEYIPTIEEHTKVSYISIGYKLALVAGFACMGDVIADDSFEWVFTNPPLVNACCLLCRTMDDLGSHKGEQDRKHVASTIECYMKQFDASEQQAYESLNKKVEDAWKEINREFMITCKDVNIHVAMRVLNFSRSVDVLYKNKDHFTHVGVEVINHIKSLFVDAIIT
What is the function of this protein?
Sesquiterpene cyclase catalyzing the production of 8-epi-cedrol.  Able to convert geranyl diphosphate to monoterpens.  Can use farnesyl diphosphate or geranyl diphosphate as substrates, but not geranylgeranyl diphosphate.  Probably not involved in artemisinin biosynthesis.
What are the official names of this protein?
Epi-cedrol synthase, 8-epicedrol synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: RL5_RENSM
Sequence: MSIETSEATVKIAPRLKTRYADEIKKTLQDDFSYVNVNQVPRLVKVVVNMGVGEAARDSKVIDGAVRDLTLITGQKPMVTKARKSIAQFKLREGMPIGAHTTLRGDRMWEFVDRLVTLALPRIRDFRGLSGKQFDGNGNYTFGLTEQVMFHEIDQDAIDKIRGMDITVVTTAKTDDEGRALLKALGFPFKSED
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: AKT1_DROME
Sequence: MNYLPFVLQRRSTVVASAPAPGSASRIPESPTTTGSNIINIIYSQSTHPNSSPTSGSAEKFSWQQSWPSRTSAAPTHDSGTMSINTTFDLSSPSVTSGHALTEQTQVVKEGWLMKRGEHIKNWRQRYFVLHSDGRLMGYRSKPADSASTPSDFLLNNFTVRGCQIMTVDRPKPFTFIIRGLQWTTVIERTFAVESELERQQWTEAIRNVSSRLIDVGEVAMTPSEQTDMTDVDMATIAEDELSEQFSVQGTTCNSSGVKKVTLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKPQVTSDTDTRYFDKEFTGESVELTPPDPTGPLGSIAEEPLFPQFSYQGDMASTLGTSSHISTSTSLASMQ
What is the function of this protein?
Serine/threonine kinase involved in various developmental processes (PubMed:9601646, PubMed:10587646, PubMed:10962553, PubMed:11740943, PubMed:12172554, PubMed:11872800, PubMed:14525946, PubMed:12893776, PubMed:15466161, PubMed:15712201).  During early embryogenesis, acts as a survival protein (PubMed:9601646, PubMed:10962553).  During mid-embryogenesis, phosphorylates and activates trh, a transcription factor required for tracheal cell fate determination (PubMed:11740943).  Also regulates tracheal cell migration (PubMed:11740943, PubMed:14525946).  Later in development, acts downstream of PI3K and Pk61C/PDK1 in the insulin receptor transduction pathway which regulates cell growth and organ size, by phosphorylating and antagonizing FOXO transcription factor (PubMed:10587646, PubMed:10962553, PubMed:11752451, PubMed:12893776, PubMed:25329475, PubMed:29025897, PubMed:24603715).  Controls follicle cell size during oogenesis (PubMed:15712201).  May also stimulate cell growth by phosphorylating Gig/Tsc2 and inactivating the Tsc complex (PubMed:12172554, PubMed:15466161).  Dephosphorylation of 'Ser-586' by Phlpp triggers apoptosis and suppression of tumor growth (PubMed:10962553).
What are the official names of this protein?
RAC serine/threonine-protein kinase, DAkt, DRAC-PK, Dakt1, Akt, Protein kinase B, PKB.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane. Note=Recruited to plasma membrane upon activation.
Protein: URED_ALKEH
Sequence: MAVAQQAWSPGADPAPSAAPVSPGWRGALRLDFARRGERTALVRRRHQGPLVVQRTFHPEGAPCHAYLLHPPGGLVGGDELDLSVEVGEGAHALMTTPGAAKFYRSSGDWSIQRQVFRLAPGATFEWLPMETILHGGSRSRLINRFELAEGARLIAWEMVALGRPGSGDHFPRGVLDQRLAVNCEQMPLLRERLSLNADDPLRTAPWGLQGQAVFATLLASPAPDGLEHDLRDALQVPPGVRMGATRCPEGLLAVRVLGPGVEPVRKTLEQAWRTIREPVVGLPPCPPRIWST
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NH106_CAEEL
Sequence: MQTTCEICEVPAHGIHFGAITCRGCAAFFRRAVNTKTNRKSCKYSSNCTNFTGKFPQCKSCRMRKCIKMGMMPEKVKVMQPISQSLEIFVSRPNLILFTNNYDKTRNYIDVSNLITRGLEILKQGFPTPLGIGKTNLERMASGVEFSTAESKIVDVVTGKSVSMVWEFDFISTAKWLTRLQDFCTLPMRIQMQLLQTIWHVWSRMYKVVKSSELRKKHADSSNLFQVLDQFHVNLGTTKLDVSWLTTYSYEEIKYFLYGIDDDIYLQSAITAASKLELTDVELTYMAAQTCFQYAQNRFAGTEIAEVCAKFQEILANDLHTYYTKDHKRTSNYAGKLSQMLKCVQEIQKSIRTTRERTTIARTFDIYITDFSNPEMFIDSGC
What is the function of this protein?
Orphan nuclear receptor.
What are the official names of this protein?
Nuclear hormone receptor family member nhr-106.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PUR7_AZOSB
Sequence: MATPLFESTIKSLPLLGRGKVRDIYAVDADKLLIVTSDRLSAFDVILPNPIPDKGRVLTAMANFWFAKLGHIVPNQLTGIDPESVVAADEREQVKGRALVVKRLKPLPIEAVVRGYVIGSGWKDYQDTGAICGIALPAGLKQAAKLPAPIFTPASKAEVGDHDENISFAQAQANCDAVLAEALAGTGKTGAGLAEEARQAAIALYSQAADYAAGRGIIIADTKFEFGIDAAGTLHLIDEALTPDSSRFWPADSYREGISPPSYDKQYVRDYLETLDWNKKAPGPDLPADVVERTAAKYREAYEKLTGLTLA
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: YQHA_ECO8A
Sequence: MERFLENAMYASRWLLAPVYFGLSLALVALALKFFQEIIHVLPNIFSMAESDLILVLLSLVDMTLVGGLLVMVMFSGYENFVSQLDISENKEKLNWLGKMDATSLKNKVAASIVAISSIHLLRVFMDAKNVPDNKLMWYVIIHLTFVLSAFVMGYLDRLTRHNH
What are the official names of this protein?
UPF0114 protein YqhA.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL23_BORBR
Sequence: MNAERLMQVILAPIVTEKATFVAEKNQQVAFRVVADATKPEIKAAVELLFKVQVESVQVLNRKGKVKRFGRFVGRRRNERKAYVALKDGQEIDFAEVK
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: GOGC2_ARATH
Sequence: MANWISSKLKAAETILQQLDQQAADSLRKDEKSETHDEVFETSPKSGSSPVSLKDQLRKKTYEGSDSGSGSQRNSTEQKPSYLSSSKKVRKPDQSHERTSAPSQSLTQDNTKLTDNDWTELLSTPNQRTSTSTSRSPGGTSAIRGLKKDGKRHGNLGKNPLVSDGKKSSSSNVVNSRGRPQKQTNKEPSDKEVSSPSDADMKNRNAPRDIFVNSTHKESEKDVSGKTPPLDDSRRSANETLPRETSPSVGKRDGRESRRSSVWGKQVREEVSQSNVSDGLTRKESSLSSDESESDYESDSSTDSERERQREERRRRRERVFAEKVATKAVAVIKERENMVARLEGEKLSLEKIVEERAKQQAQEAAELQTNMMETLEAADLEKQKHNNTRMEVLTRLAGLEAENAELTRSLAAGQKKLETQIDQVAVLKQQVELKESTLEELKRNTFNIGGRGTTLKQLDTSRGDKFEHQMLEAEISLLTDKIGRLQDKATKLEADIEMMRKELEEPTEVEIELKRRLNQLTDHLIQKQSQVEALSSEKATILFRIEAVSRLIEENKGMSATEASSQDLEAGDWELSGSKFKPAFQDKIRSGKKHLGWLVMQLNAIFISGTVFLRRNPTAKIWAVVYLVCLHLWVLYILLSHSDASSSGELRSGAVISLENFSNSSLQ
What is the function of this protein?
Golgi matrix protein playing a role in tethering of vesicles to Golgi membranes and in maintaining the overall structure of the Golgi apparatus.
What are the official names of this protein?
Golgin candidate 2, AtGC2.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Note=Probably located to cisternal rims of cis or medial Golgi.
Protein: RL1_PSYCK
Sequence: MSKLTKRQKEINSRIEHEKQYTIEEAVQILNDLPALKFKESIDIAVNLGVDPRKSDQVVRGATNLPAGTGKTKRVAVFAQGAAAEAAKEAGADIVGFEDLAESIKAGNMDFDVVIAAPDAMRVVGQLGTILGPRGLMPNPKVGTVTPNVAEAVLNAKAGQAQYRVDKAGIIHTTIGQVGFTAEQVIQNAEALISDLRRAKPATSKGTFIKKITLSSTMGPGLSIDPVPYRTAK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.