PharMolix/UniProtQA huggingface dataset:
Protein: OLFM4_HUMAN
Sequence: MRPGLSFLLALLFFLGQAAGDLGDVGPPIPSPGFSSFPGVDSSSSFSSSSRSGSSSSRSLGSGGSVSQLFSNFTGSVDDRGTCQCSVSLPDTTFPVDRVERLEFTAHVLSQKFEKELSKVREYVQLISVYEKKLLNLTVRIDIMEKDTISYTELDFELIKVEVKEMEKLVIQLKESFGGSSEIVDQLEVEIRNMTLLVEKLETLDKNNVLAIRREIVALKTKLKECEASKDQNTPVVHPPPTPGSCGHGGVVNISKPSVVQLNWRGFSYLYGAWGRDYSPQHPNKGLYWVAPLNTDGRLLEYYRLYNTLDDLLLYINARELRITYGQGSGTAVYNNNMYVNMYNTGNIARVNLTTNTIAVTQTLPNAAYNNRFSYANVAWQDIDFAVDENGLWVIYSTEASTGNMVISKLNDTTLQVLNTWYTKQYKPSASNAFMVCGVLYATRTMNTRTEEIFYYYDTNTGKEGKLDIVMHKMQEKVQSINYNPFDQKLYVYNDGYLLNYDLSVLQKPQ
What is the function of this protein?
May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase.  In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis.  May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation.  Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin.
What are the official names of this protein?
Olfactomedin-4, OLM4, Antiapoptotic protein GW112, G-CSF-stimulated clone 1 protein, hGC-1, hOLfD.
What are the subcellular locations of this protein?
Secreted, extracellular space. Mitochondrion. Note=Subcellular location is not clearly defined: has been shown to be secreted (PubMed:16566923), but also in the mitochondrion (PubMed:15059901 and PubMed:20724538), cytoplasm and plasma membrane (PubMed:20724538) and in the nucleus (PubMed:15059901).
Protein: RS10_SHESM
Sequence: MQNQRIRIRLKGFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERYTVLISPHVNKDARDQYELRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: HYPA_CUPNH
Sequence: MHELSLAGGILQLLEDAARRERFARVTLLRLEAGKLCGVEVRALRFALEAIASGTCLEGACIEIEEPEGQAWCLQCNAAVALAERGAPCSGCGGYRLQPTAGTELRVMDMLVEDHWCPE
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: BPT_PSEPW
Sequence: MTELARLKFYATQPHSCSYLPDEQATTLFLDPSQPMDVHVYADLSEMGFRRSGDHLYRPHCQNCNACVPARIPAARFIPNRQQRRILKRNADLTVTAARPAFKEEYFDLYRRYIETRHADGDMYPPSRDQFSTFLVRDLPFCWFYEFRLAGRLLAVAVCDLLPNGLSAVYTFYEPDEERRSLGRFAILWQITEALRQDLEAVYLGYWIKNCKKMNYKTQYRPIELLINQRWVTLN
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_SPIOL
Sequence: MLRDGNEGMSTIPGFNQIQFEGFWRFIDQGLTEELSKFPKMEDTDQEIEFQLFVETYQLAEPLIKEKDAVYESLTYSSELYVSAGLIWKTRREMQEQTILIGNIPLMNSLGTFIVNGIYRIVINQILQSPGIYYRSELDHNGISVYTGTIISDWGGRSELEIDRKARIWARVSRKQKISILVLSSAMGSNLREILDNVCYPEIFLSFLNDKEKKKIGSKENAILEFYQQFACVGGDPVFSESLCKDLQKKFFQQRCELGRIGRRNMNRRLNLDIPENNTFLLPRDILAAADHLIGMKFGMGTLDDMNHLKHKRIRSVADLLQDQFGLALVRLENVVRGTISGAIRHKLIPTPQNLVTSTPLTTTFESFFGLHPLSQVLDRTNPLTQIVHGRKLSYLGPGGLTGRTASFRIRDIHPSHYGRICPIDTSEGINVGLIGSLAIHARIGPWGSLESPYYEISERSKRVQMLYLSPSRDEYYMLASGNSLALNQGIQEEQVVPARYRQEFLTIAWEQVHFRSIFSFQYFSIGASLIPFIEHNDANRALMSSNMQRQAVPLSQSEKCIVGTGLERQVALDSGVLAIAEHEGKIIYTNTDKIVLLGNGNTVSIPLVMYQRSNKNTCMHQKPQIPRGKCVKKGQILADGAATVGGELALGKNVLVAYMPWEGYNFEDAVLISERLVYEDIYTSFHIRKYEIQTYVTSQGPEKVTSEIPHLEAHLLRNLDKNGIVRLGSWVETGDILVGKLTPQMAKESSYAPEDRLLRAILGIQVSTSKETCLKLPIGGRGRVIDVRWIQKKGGSSYNPETIHVYISQKREIKVGDKVAGRHGNKGIISRILLRQDMPYLQDGRPVDMIFNPLGVPSRMNVGQIFECSLGLAGSLLDRHYRIAPFDERYEQEASRKLVFSELYEASKQTANPWVFEPEYPGKSRIFDGRTGDPFEQPVIIGNPYILKLIHQVDDKIHGRSSGHYALVTQQPLRGRAKQGGQRVGEMEVWALEGFGVAHILQEMLTYKSDHIKARQEVLGTTIIGGTIPNPEDAPESFRLLVRELRSLALELNHFLVSERNFQINRMEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SUCC_DESAL
Sequence: MKIHEYQAKELFANYGVPVPKGKPVFSVDEAVEAAKELGDFPVVVKAQIHAGGRGKGGGVKLAQNIDEVKTIAGEILGMQLVTHQTGPEGQKVQKLLVEQGLDIAKELYFSIIVDRATAKIVIMCSEAGGMDIEEVAASTPEKIIKVPVDPLLGVQGYHCRQAAYRLNLPPAAIKPFIKMVQGLYKMFMDTDCSLLEINPLVLTGDDGIIALDAKINFDDSALYRHKDIQEYRDLDEEEPLEVEASKFNLNYIKMDGNVGNMVNGAGLAMATMDIIKQAGAEPANFLDVGGGANAEQVENGFRIILSDKNVKGILINIFGGILRCDVLASGVVEAAKKVGLNVPVVVRMEGTNVEEGRRILAESGLNLTGAEDLKDAAAKVAQIVQ
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: MOBA_VIBCH
Sequence: MITTQTLPTLQPSDTSWVILAGGQASRMGGQDKGLIQLNGQPLVQHVIDKLAPQTPTLLINANRNQSQYQQFAPVISDEFPDYPGPLGGIHAGLSHAPTDWVGFVPCDSPLICDDLVARFCQAVKPESDILVAHDGEHQQPVFTLFHKRVLPKLSAFLARGDRKIILLYDECHTSYVDFSDAPSCFFNLNTPQELAQFGALHP
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_SPHAL
Sequence: MTTKILPSQPKVGMVSLGCPKALVDSERILTKLRADGYGLSPDYAGADVVLVNTCGFLDSAKEESLEAIGEAMAENGRVIVTGCMGKEADVIRARFPNVLAVTGAHQYEQVVEAVHDAAPPTQGPFVDLVPEGGLKLTPRHYSYLKISEGCNHSCAFCIIPDLRGKLVSRRIDAVLREAEKLVAAGTKELLVISQDTSAYGVDIRHDPRQWHGREIRAHMTDLARELGQLRTSEGRAPWVRLHYVYPYPHVDAVIPLMAEGLLTPYLDIPFQHASPSVLKRMKRPANEAKVLERLKSWRAIAPDIAIRSSFVVGFPGETEADFQYLLDWLEEAQLDRVGAFRFEPVAGAQANALPEPVPDEVKEERYQRIMAKTAAISAAKLEAKIGRTLPVIIDEVGEADEDGSIGATGRSQADAPEIDGHVYLRDVAATLKAGDIVDVEIEDADEHDLFGVVT
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMA1_ALLMI
Sequence: MAQENPKMHNSVISKRLGAEWKLLSEAEKRPFSDEAKRLRAMHMKEYPDYKYRP
What are the official names of this protein?
SRY-related protein AMA1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RLMH_BRUA1
Sequence: MRVSVFAVGRMKSGPERELVERYFDRFAKAGPPLGLEFAGVSEIPESRGQTAQLRKAEEAQRIHEALDNAKSGGTSSGGAALILLDERGKTLGSEAFAAIVGRMRDDGKRQLIVAIGGPDGHDPALRSRADLVLALGELTWPHQIARILIAEQLYRAATILAGHPYHRS
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_DESPS
Sequence: MILVIDVGNSHTVTGLYDHGKLIGHWRLKTDRDRTSDELAIRYHGLFIMEGIDPRQITDIVLASVVPTLSSAWIRCCERHFGKHLNQPVMDLSVTKLAPLVRVETDNPHEVGIDRLVNAYGAWHTRKTDLIVIDFGTAITFDCVTSDCVYIGGVILPGIAISLDALATRTAKLPMVDVRDVPSSLIGKNTVHAMQSGILYGYGAMVDGIVEGIQKEMLGGKRRAEVIATGGMANLIEPFTTTIEHIDKLLTLDAMELILHALKKKQ
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EI3F2_DROAN
Sequence: MLCNFNLQAKVVLQPLVLFQIIDSYERRPKDATQIIGTLLGRSNGKEITITNCFTVLHKEHPDSARIDLDLGYANDMLELNQLTYPQEKVLGWFSTGKSVSRSALLLHDYYSRECSDGQPLHLLVDATLKGQRLSTRLYCGVEMGVPGGTKGLMFSLVPLEMASDSAEMVALRLMQKQNLQPGAKQVGRILPELVQVVEATRELQLRLDLVLRYINDVLARKRRPDNVVGRALHDTLTSVPLVDTDNFKLMFNANVRDMLMAITLSTMIKTQLQISEKLFAMPDH
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit F-2, eIF3f-2, Eukaryotic translation initiation factor 3 subunit 5-2.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit F family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P23A3_MOUSE
Sequence: MLRTRPRSPSADPAPCWSPQTPAPSPAKRRRLHQEPACPEPLAQPELEAPAEPTTSVVFLAAGSALQLPLDGVDLLLEPEPTSVLQVSLQGHTILLVPEGLQDSTHFGQPGFVAISPQGAAAQDGPQDHLVGLQEETFCEYFYQEDVCDEDADLEFLEHWASPPDDQANGNFSSIPGVPSPLSQDQVPGPSTGAEQYSPRFIWELDINMLGPFPGSPLQPLPPSPSRNPQEQLPPCPPCSPRAPRRARKRLVYE
What are the official names of this protein?
Proline-rich protein 23A3.
What is the protein family that this protein belongs to?
Belongs to the PRR23 family.
Protein: CENPS_YEAST
Sequence: MNDDEDRAQLKARLWIRVEERLQQVLSSEDIKYTPRFINSLLELAYLQLGEMGSDLQAFARHAGRGVVNKSDLMLYLRKQPDLQERVTQE
What is the function of this protein?
dsDNA-binding component of a FANCM-MHF complex involved in DNA damage repair and genome maintenance (PubMed:20347428).  FANCM-MHF promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork (By similarity).  Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis.  Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly (PubMed:22561346).
What are the official names of this protein?
Inner kinetochore subunit MHF1, CENP-S homolog, Constitutive centromere-associated network protein MHF1, MHF histone-fold complex subunit 1, MPH1-associated histone-fold protein 1.
What is the protein family that this protein belongs to?
Belongs to the TAF9 family. CENP-S/MHF1 subfamily.
Protein: GCH1_BRUME
Sequence: MDARILQDNDDTSLPVNQASVTRIHKKPGKAEAEAAVRTLLLWAGEDPDREGLLETPKRVAKAYQELFGGYSESPEEVLGTTFEEVAGYDDMVLVKDISFFSHCEHHMVPIIGKAHVAYLPEGRVVGLSKIARVVDIFARRLQTQESITAQIADSIQRILKPRGVAVMIEAEHMCMAMRSIRKQGSSTITTTFTGDFKEKADQQVRFMTLIRT
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: UPPP_STRSV
Sequence: MFIIEIFISIIYGIIEGITEWLPISSTGHLILIQDFIQFKNQSPAFMEMFNVVIQLGAILAVVVIYFDKLNPFKPGKSARQVQKTWQLWAKVVVAALPAAVIGLFLDDWFEAHFYNLVSVSVMLIVYGAAFIYLERREHEEPAVTDLASLPYKTALQIGLFQILALFPGTSRSGATIVGGLLNGVSRSVVTEFTFYLGIPIMFGASGWKILKFIKNGNGLGFGQIFLLLVAMGVAFGVSLVVIRFLTDYVKKHDFTIFGKYRIGLGGVLLVYAAIKALMG
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYB1_CAEBR
Sequence: MDAQGDAGAQGGSQGPRPSNKRLQQTQAQVDEVVGIMKVNVEKVLERDQKLSQLDDRADALQEGASQFEKSAATLKRKYWWKNIKMMIIMCAIVVILIIIIVLWAGGK
What is the function of this protein?
Involved in the targeting and/or fusion of transport vesicles to their target membrane.  Acts in neuronal exocytosis of synaptic transmission.  Likely to have a role in cholinergic transmisson.  Required for viability, coordinated movement and M3 pharynx motor neuron function (By similarity).
What are the official names of this protein?
Synaptobrevin-1, Synaptobrevin-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Cell membrane. Synapse, synaptosome.
Protein: THIC_THET8
Sequence: MTQLEAARKGKITEEMAYVAEKEGVSPEFVREGVAAGRIVIPRNPNHKTLTDFKGIGEGLSVKVNANLGTSYDYVDVEEEVEKARVAIQYGADTVMDLSTGGDLKAIRKRILEVATVPLGTVPIYEAEFRAARRKNFFDMSADELFQVIEEHGKEGVDYITVHVGVTLKNLEVYRNSPRTTGIVSRGGGLMAAWMLHRGEENPLYARFDDLLDIARTYDMTLSLGDGLRPGSLADSTDRAQIAELLTIGELVERARRAGVQAMVEGPGHIPLNEVAANVQIQKKLTGHAPFYILGMLPVDTAAGFDHIAGAIGGALAGWWGADMLCYLTPAEHLGLPTPEHVKQGVIAFKIAAHAADVARGNKRALERNRRMSEARYRLDWEGQFALALFPEEARRLKEERGSKTKACSMCGPFCPMNLVEAVLKGKGRMELPVA
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: COF_ECOSE
Sequence: MARLAAFDMDGTLLMPDHHLGEKTLSTLARLRERDITLTFATGRHALEMQHILGALSLDAYLITGNGTRVHSLEGELLHRDDLPADVAELVLYQQWDTRASMHIFNDDGWFTGKEIPALLQAFVYSGFRYQIIDVKKMPLGSVTKICFCGDHDDLTRLQIQLYEALGERAHLCFSATDCLEVLPVGCNKGAALTVLTQHLGLSLRDCMAFGDAMNDREMLGSVGSGFIMGNAMPQLRAELPHLPVIGHCRNQAVSHYLTHWLDYPHLPYSPE
What is the function of this protein?
Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).
What are the official names of this protein?
HMP-PP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family.
Protein: Y4160_CLOAB
Sequence: MKKKLKSVLIWFLIFTFNLSLGSFREVFADNNDAVLATAITLSKNEDKLLVNQTDTLTAVVTPDNASNKGVTWSSSDTNTAAVDQNGKITALKVGTVTITAATQDGSNLSSSCTVSITRLANSIVLNKMVDKLPVGQTDLLTALVRPLDSAVKDVTWTTSDPSVVSVDDKGNIKALKLGMAVVTAAVNDGRNLHASCNVYVTNLLSKRKKADLVVTLDNSMNIDKTTFKDKLNKYIESKLKGSNIDYTIQSIQGYKSKKVLIIQDQPAWESGTKVYDDIKQEGYTSDVITANQISSTELTQYSHIYIPSDQAQSFYDELNQNYSKLEAWTKGGGILIFNAADEGHHSGQWQGSFLGLTHTPSDFQPTITIVKQDPILTANLKTTITGNYAAHSQFTSYPSNSIIFAVGNKNLPTILEYRYGDGLVFAQTTTAEFYATNSGDLSPYLDNEIKYTIQKTLGRSFSDILKKPTWRENSEKFVINLGDTLANDVKENSMAQTLAELESNKAYVTLIGNNNNKDTLNSFINKNDGRGMFIDNSDLDGALSKAGDYIMTVLNKEEQNSNMFLTDDYINYNESSSEDVSWSYTQDCKHLNYDNDFVNCSKTGDIALDNDLGISDFANGQWVNNEINEFKKPGKYTIAYKFKDNAIVNETVNVNRKPTPIFTAYTAQDAVSGKYDVVIKDEDKSYDIDHENSDGDRKGIVNSKFQWKEVTQGVNDTWHDGKLPSGQDSNKDFIVKLEVQDLEGQWSNPLVKYITTRNSNVAPHAQFTESAEEMPVDQLNNDASVGMDAIFTDESYDANGDSIREHWIVTDNNGNTIYDSTSMPKASVFVGKPLGTYNVTLTCDDGPTPKVGAMLTSDSYTLQLKLVPINHKPVAKFEVDNTSKVPADIKITEDSTDPDGDKITEKDWTVTDDKGKVVLQTENKLPDLSNLNGSYTITLKVKDSPVGLPELWSDPLSKTIIVEGAK
What are the official names of this protein?
Uncharacterized protein CA_P0160.
Protein: URE1_STAA2
Sequence: MSFKMTQNQYTSLYGPTVGDSIRLGDTNLFAQIEKDYAVYGEEATFGGGKSIRDGMAQNPRVTRDDVNVADLVISNAVIIDYDKVVKADIGIKNGYIFAIGNAGNPDIMDNVDIIIGSTTDIIAAEGKIVTAGGIDTHVHFINPEQAEVALESGITTHIGGGTGASEGSKATTVTPGPWHIHRMLEAAEGLPINVGFTGKGQATNPTALIEQINAGAIGLKVHEDWGATPSALSHALDVADEFDVQIALHADTLNEAGFMEDTMAAVKDRVLHMYHTEGAGGGHAPDLIKSAAFSNILPSSTNPTLPYTHNTVDEHLDMVMITHHLNAAIPEDIAFADSRIRKETIAAEDVLQDMGVFSMISSDSQAMGRVGEVITRTWQVAHRMKEQRGPLDGDFEHNDNNRIKRYIAKYTINPAITHGISEYVGSIEPGKLADIVLWDPIFFGVKPELVVKGGLINSAVNGDANGSIPTSEPMKYRKMYGQYGGNLTSTSMTFVSKTAYENGINRALNLKRMVRPVKNIRQLSKADMKNNSATPKLDVDPQTYEVYVDGENITSNAATELPLTQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_FRAAA
Sequence: MTTAVLPRVGIGVDVHPFAAGRPCWVACLEWPGETGLAGHSDGDVAAHATCDALLTASCLGDLGKVFGTDRPEYAGASGAVLLAETARLLAVGGWVIGNVSVQVIGNRPRMAARREQAQAAMSAALGASVSLSATTTDGLGLTGRGEGLAAIATALVVRA
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: NNR_ARCFU
Sequence: MEFISSRDMQILDTNCEYFGLSRMLLMENAGKGVAEEVMKRFYEGKVQIFAGSGNNGGDGFVAARHLKGFDVEIFLLSKPKTELAIKNLEICRKAGFPVKEGLPEEIDADIVIDAMLGTGVRGRLREPYSTAVKMINESDAFKVAVDVPTGLDPDSGSYEEAVKADLTVTFHKAKPGLAKAREVCGEVAVKDIGIPESFENLCGPGDVAFSYKRYEDAHKGVHGKVLVVGGGDYTGAPALASLAALYAGADIVTTAVPMAIRKVVASFSPNLIVRGVGEERIEMKNLEELEELVKRHDVVVAGMGVGENPEFKEVVEELLKSCKKAVLDAQGIVDSVPENCECILTPHRGEFGRVFGDTEVQKAALKAKAVILLKGREDVITDGSRVKVNRSGNAGMTVGGTGDVLAGIAAAFLCNDDAFHSACAAAFLNGLAGDVCFEKFGYNYTATDLVKAIPEAILRCKSF
What is the function of this protein?
Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP.  This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity).
What are the official names of this protein?
Bifunctional NAD(P)H-hydrate repair enzyme Nnr, Nicotinamide nucleotide repair protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NnrD/CARKD family.
Protein: RL6_STRZT
Sequence: MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIRVEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSKLVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGKGIRYVGEFVRRKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: MEP5_ARTOC
Sequence: MHGLLLAAGLLSLPLHVLAHPQPGTSLAGRAVDLNAYRMADRASYMSSDEMQAQQPHIASVSAGGYVETATEVVKRVMPGMTFRLVDDHYVGVSGISHVYFRQTMHGMDIDNSDFNVNIGKDGKVLSYGNSFYTGPAPDKAPMVKRDFSDPMQALHGVRKALNLPITADKATVKTVNEHEVTFMGTTGALSDPSAKLCYMAKEDGSLALTWRVETDMGDNWLLSYVDAKSTDQVHNVVDYVSHATYQVYRWPIPDPTEGKREILENPWNLRTSPFTWISDGKNNYTTTRGNNAIAQANPDGGNEYLNNYRPNNKNLKFEYPYSPNMSPPKTYIDASITQLFYSANMVHDLYYMLGFTEKAGNFQVNNRGQGGKGNDFVILNAQDGSGTNNANFATPPDGQPGRMRVYIWTKAQPARDSSFEAGTVIHEYTHGLSNRLCGGPANSACLNGLESGGMGEGWGDFFATAIRLKPNDNRNANYVHGEWVNNSPKGNRLFPYSTSLKTNPLVYTSCNKYNEVHAIGTVWASILYEVLWNLIDKHGKNDGPTPVFENGVPKDGKYLSLKLVLDGMAIQPCKPNFVQARNAIIDADKNLTKGANKCELWKAFAKRGLGTGAKYDPKNRTGSTAVPKECQ
What is the function of this protein?
Secreted metalloproteinase probably acting as a virulence factor.
What are the official names of this protein?
Extracellular metalloproteinase 5, Fungalysin MEP5.
What is the protein family that this protein belongs to?
Belongs to the peptidase M36 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RIMP_KORVE
Sequence: MIEIEKVREIVERVARDYGLEVVEVEFRGGGKARMLRITIDKPEGVTHDDCSHVSNEVSTILDVEDVVPGASYTLEVSSPGLDRKISKPADFERFTGSLVKVSTREPLDGNRHFEGRLESFADGKLTIDLNAVPQRGQKKQKGPKAPVVERKVEIALADVEKANLVPEI
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EUTE_ECOLI
Sequence: MNQQDIEQVVKAVLLKMQSSDTPSAAVHEMGVFASLDDAVAAAKVAQQGLKSVAMRQLAIAAIREAGEKHARDLAELAVSETGMGRVEDKFAKNVAQARGTPGVECLSPQVLTGDNGLTLIENAPWGVVASVTPSTNPAATVINNAISLIAAGNSVIFAPHPAAKKVSQRAITLLNQAIVAAGGPENLLVTVANPDIETAQRLFKFPGIGLLVVTGGEAVVEAARKHTNKRLIAAGAGNPPVVVDETADLARAAQSIVKGASFDNNIICADEKVLIVVDSVADELMRLMEGQHAVKLTAEQAQQLQPVLLKNIDERGKGTVSRDWVGRDAGKIAAAIGLKVPQETRLLFVETTAEHPFAVTELMMPVLPVVRVANVADAIALAVKLEGGCHHTAAMHSRNIENMNQMANAIDTSIFVKNGPCIAGLGLGGEGWTTMTITTPTGEGVTSARTFVRLRRCVLVDAFRIV
What is the function of this protein?
Acts as the second step in ethanolamine degradation by converting acetaldehyde into acetyl-CoA.  May play a role in bacterial microcompartment (BMC) assembly or maintenance.  Directly targeted to the BMC (By similarity).  Its heterologous expression in S. cerevisiae increases the level of acetylating acetaldehyde dehydrogenase activity (PubMed:26384570).
What are the official names of this protein?
Acetaldehyde dehydrogenase (acetylating) EutE, Ethanolamine utilization protein EutE.
What is the protein family that this protein belongs to?
Belongs to the EutE/PduP family.
What are the subcellular locations of this protein?
Bacterial microcompartment. Note=Probably located inside the BMC.
Protein: SYK_UREPA
Sequence: MERKFSDQELIRRTHLQELKNQNKNPFLITKVDRSMFLKDFAEKYKNFSKEELHNMDLEKLTLAGRLIGIRQTFGIIQDFSAKLQIYINKKNVAPEVFSTFKSLDIGDIIELEGVAMKTNSDEITLNVTNIRLVAKSLKVLPEKYHGLVDEEIKARQRYLDLIVNDETKNTFIKRSLIIREMRNWLDNKGFFEVETPVLQDILSGAAARPFITHHNTLNKEYYLRIATEIALKKCIIGGFEKVYEIGRIFRNEGMDSTHNPEFTSVELYIAYVDLWYIMQLTEDLIRHIATKLNLLNPTFRGFSIDLNKPFKKAHMVDLINEYVGVNFFEVKSDEQAIELAKKHHVKLLDHQKNFGHIVNAFFETFVEEKLVEPTFVYGHPLQVSPLTKKNQSDPRFVDRFELFICQKEFANAYSEINDPIDQYERFIAQLEEAKLGNDEASELDMEFIEALEYGMPPTGGLGIGVDRLVMLLTSNDSIRNVLLFPHMKDKTK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.