PharMolix/UniProtQA huggingface dataset:
Protein: GPR33_MOUSE
Sequence: MDLINSSTHVINVSTSLTNSTGVPTPAPKTIIAASLFMAFIIGVISNGLYLWMLQFKMQRTVNTLLFFHLILSYFISTLILPFMATSFLQDNHWVFGSVLCKAFNSTLSVSMFASVFFLSAISVARYYLILHPVWSQQHRTPHWASRIALQIWISATILSIPYLVFRTTHDDHKGRIKCQNNYIVSTDWESKEHQTLGQWIHAACFVGRFLLGFLLPFLVIIFCYKRVATKMKEKGLFKSSKPFKVMVTAVISFFVCWMPYHVHSGLVLTKSQPLPLHLTLGLAVVTISFNTVVSPVLYLFTGENFKVFKKSILALFNSTFSDISSTERTQTLNSETEI
What is the function of this protein?
Orphan receptor; could be a chemoattractant receptor.
What are the official names of this protein?
Probable G-protein coupled receptor 33.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MINC_BURCH
Sequence: MSLKKSPFFELRSGSVDTLLFTVKTTDLDALRAELVKRFEATPEFFADDVVAIDVRRLADGERVALADIRQMLNDVRMRPVGVVALATQGWAGEAGLPLLEARDRRAPAAKPADEAEPAAVPAVETAAAPAAAAAPEQPSEPAPTLVQAGGQTLVIDRPLRSGQQIYAKGDLVVLAPVSHGAEIIAEGNIHIYAPLRGRALAGVHGNHDARIFCTCLEPELISIAGIYRTTENPLPADVLGKSVQIRLEEEKLMIEPLRLT
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: ZO2_MOUSE
Sequence: MEEVIWEQYTVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPADGLLQENDRVVMVNGTPMEDVLHSFAVQQLRKSGKIAAIVVKRPRKVQVAPLQGSPPLSHDDRGFEVIEEFDGRSFRSGYSERSRHSSHDMLSHSWEGNRERGRPHQRTQSRERERSRGRSLERGLDQEDYGRSRERSRGRSLERGLDRDFVSRDHSRGRSIDRDYDRDYERSYHEAYEPDYGGGYSPSYDRRAHPETRYERSRSREHLRSRSPSPESRSRHEHKGQHDPDRPIGVLLTKSKANEEYGLRLGSQIFIKEMTRTGLATKDGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSKQTLINIPALNDSDSEVEDISEIESNRSFSPEERRQQYSDQDYHSSTEKLKERPSSREETSGRLSRMGATPTPFKSTGDITAAGVTEASREPRYQEEGPVPQPRTAPRVFLRPSPEDEAIYGPNTKMVRFKKGDSVGLRLAGGNDVGIFVAGIQEGTSAEQEGLQEGDQILKVNTQDFRGLVREDAVLYLLEIPKGETVTILAQSRADVYRDILACGRGDSFFIRSHFECEKETPQSLAFTRGEVFRVVDTLYDGKLGHWLAVRIGNELEKGLIPNKSRAEQMASVQNAQRENAGDRADFWRMRGQRSSGGVKKNLRKSREDLAAAVSVSTKFPAYEKVLLREAGFKRPVVLFGPIADIAMERLATELPDLFQTAKTEPKDAGSEKSSGVVRLNTVRQIIEQDKHALLDVTPKAVDLLNYTQWFPIVIFFNPDSRQGVKTIRQRLSPTSNKSSRKLFDQANKLKKTCSHLFTATINVNSANDGWFGSLKDSIQQQQNEAVWVSEGKMEGMDDDAEDRMSYLTAMGADYLSCDSRLISDFEDTDGEGGAYTDNELEEPAEEPLVSSITRSSEPVQHEENIRKSSPEPRAQMRRAASRDQLRDASPPPAFKPEPPKARSQNREDSFDYSKSNLPATAGSEIPGGSTKGYPPPIAAKPAFGRPILKPSTPVPMPESEEVGESTEEQEDAPRSVLGRVKIFEKMDHKAKLQRMQELQEAQNARIEIAQKHPDIYAVPIKAPKPDAGLPPHMSSRPPEPQKAPSRLYQDTRGSYGSDPEEEEYRQQLAAHSKRGYYSQPSRYRDTEL
What is the function of this protein?
Plays a role in tight junctions and adherens junctions (PubMed:10026224).  Acts as a positive regulator of RANKL-induced osteoclast differentiation, potentially via mediating downstream transcriptional activity (PubMed:22437732).
What are the official names of this protein?
Tight junction protein ZO-2, Tight junction protein 2, Zona occludens protein 2, Zonula occludens protein 2.
What is the protein family that this protein belongs to?
Belongs to the MAGUK family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus. Cell junction, tight junction. Note=Also nuclear under environmental stress conditions and in migratory endothelial cells and subconfluent epithelial cell cultures.
Protein: VGRGA_DICD3
Sequence: MANSTGLQFTVKVGALPDTTFAVVDFELSEALNQPFALSLNLASSLPGIDFGAVLDQPCELLVWYEGELQRRVSGIVSRFAQGDTGFRRTRYQAEVRPALWRLGLRTNARIFQTQKPDAIIGTLLEEAGITDFAFALRHEHAVREYCVQYRESDLAFINRLAAEEGLFYFHEFEAGKHRVVFADDAGALTKGPELFFNLATQGLSEGAYVRRFRYAEAVSTAEVALKDYSFKTPAYGLLHNKMSSELDHQRETYQHFDYPGRFKQDPSGKAFTGYRLDALRAGAMTGEGESNAAELMPGSSFTLTEHPNPAFNLAWQVVAVTHSGQQPQALEEESGGEPTTLSNSFEVVKGTTTWRAAMPYKPMVDGPQIATVVGPAGEEIYCDEFGRIKLQFPWDRYGASDDQSSCWVRVSQGWAGGQYGLIAIPRIGHEVVVSFLEGDPDQPIVTGRTFHATNPSPYPLPASKTRTSLRTSTHKGAGFNELRFEDQAGQEEVFIHAQKDMNTVVLNNRSTSVNASHTENVGGDQTVVVQHNQTVSVKENQVTEIQGEQTVAVTQNRNTTVNDNESLQVKNNIAIQSQSGDILIATAGGFIAIDKDGNISITGKGLVLNGTRIDLN
What is the function of this protein?
A Vgr protein that is probably part of a type VI secretion system (T6SS).  May be required for export of proteins involved in Rhs-mediated cellular contact-dependent growth inhibition (CDI).
What are the official names of this protein?
Putative type VI secretion system protein VgrGA.
What is the protein family that this protein belongs to?
Belongs to the VgrG protein family.
Protein: CYB_CTEVA
Sequence: MTNIRKTHPIMKIINHTFIDLPAPSNFSAWWNFGSLLGICLILQIMTGLFLAMHYTADTTSAFSSVTHICRDVNYGWMIRYMHANGASMFFICLFIHIGRGMYYGSYLLLETWNIGIILLFTTMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFILPFMITALAMVHLLFLHETGSNNPTGINSDSDKIPFHPYYTMKDIMGFMMMFMTLLTLVLFSPDMLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILITLPMTHTAKQRSMMFRPMSQCMFWILVANLITLTWIGGQPVEPPFILIGQLASLSYFTIILIMMPLINLLENKLMKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RPPH_ECO55
Sequence: MIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGESAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLLQLVSGDAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMSLQENTPKPQNASAYRRKRG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: KDTX_SERMA
Sequence: MSSRKSLSVVMIAKNEAGLLPDCLRSVAWADEIIVLDSGSEDDSVAVAESLGAKVFTHTDWQGFGKQRQLAQSYASHDYVLMIDADERVTPELRQSIERVLNAPDDGAVYSCARRNLFLGRFMRHSGWYPDRVNRLYANSRYRYNDDLVHELLNIGDAKVIPLSGDMLHLTCRDFFAFQRKQLRYAEEWATQRHRAGKRCGYLSILTHTLGAFVKTWLLRAGFLDGKQGLLLAVVNAQYTFNKYAALWALGRNYSEK
What are the official names of this protein?
Lipopolysaccharide core biosynthesis glycosyltransferase KdtX.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. WaaE/KdtX subfamily.
Protein: SINA5_ARATH
Sequence: METDSIDSVIDDDEIHQKHQFSSTKSQGGATVVISPATSVYELLECPVCTNSMYPPIHQCHNGHTLCSTCKSRVHNRCPTCRQELGDIRCLALEKVAESLELPCKYYNLGCLGIFPYYSKLKHESQCNFRPYSCPYAGSECAAVGDITFLVAHLRDDHKVDMHTGCTFNHRYVKSNPREVENATWMLTVFQCFGQYFCLHFEAFQLGMAPVYMAFLRFMGDEDDARNYTYSLEVGGSGRKQTWEGTPRSVRDSHRKVRDSHDGLIIQRNMALFFSGGDKKELKLRVTGRIWKEQQNPDSGVCITSMCSS
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:12226665).  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates (PubMed:12226665).  Mediates the ubiquitination and proteasomal-dependent degradation of NAC021/NAC022, a transcription activator that functions downstream of the auxin signals, thereby acting as a down-regulator of auxin signals (PubMed:12226665).  Involved in the formation of lateral roots (PubMed:12226665).  Is antagonist to SINAT1, SINAT2, SINAT3 and SINAT4 by suppressing FREE1 ubiquitination and degradation mediated by SINAT1, SINAT2, SINAT3 and SINAT4, and promoting FREE1 accumulation (PubMed:32786047).
What are the official names of this protein?
E3 ubiquitin-protein ligase SINAT5, RING-type E3 ubiquitin transferase SINAT5, Seven in absentia homolog 5.
What is the protein family that this protein belongs to?
Belongs to the SINA (Seven in absentia) family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly nuclear. Partially cytoplasmic. Multivesicular body (PubMed:32786047).
Protein: AEEP_THEMA
Sequence: MSRIVNVKLSLKRYEYEKPFHITGSVSSESRNVEVEIVLESGVKGYGEASPSFRVNGERVEALLAIENAVREMITGIDVRNYARIFEITDRLFGFPSLKAAVQFATLDALSQELGTQVCYLLGGKRDEIETDKTVGIDTVENRVKEAKKIFEEGFRVIKIKVGENLKEDIEAVEEIAKVTRGAKYIVDANMGYTQKEAVEFARAVYQKGIDIAVYEQPVRREDIEGLKFVRFHSPFPVAADESARTKFDVMRLVKEEAVDYVNIKLMKSGISDALAIVEIAESSGLKLMIGCMGESSLGINQSVHFALGTGAFEFHDLDSHLMLKEEVFRGKFIQDGPRMRVKDQ
What is the function of this protein?
Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L-Glu and has probably a role in the metabolism of the murein peptide, of which L-Ala-D-Glu is a component.  Is also able to catalyze the reverse reaction and the epimerization of a broad range of other dipeptides; is most efficient with L-Ala-D/L-Phe, L-Ala-D/L-Tyr, and L-Ala-D/L-His.
What are the official names of this protein?
L-Ala-D/L-Glu epimerase, AE epimerase, AEE.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family.
Protein: THPA_THADA
Sequence: NLPNSVDWWKKGAVAAVKNQRXCGSCXAFSSIKTS
What is the function of this protein?
Specificity similar to that of papain.
What are the official names of this protein?
Thaumatopain.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
Protein: DNAJ_XANC5
Sequence: MSKRDYYEVLGVARGASDEELKKAYRRCAMKHHPDRNPGDAAAEAAFKECKEAYEVLSDGNKRRAYDAHGHAAFEHGMGGGGGPGGPDMGDIFGDIFGNIFGGGAAGPRAARRGADVGYVLELDLEEAVAGIERRIEIPTLVECAPCHGSGSEDGKVETCGTCHGRGQVRIQRGIFAMQQSCPHCDGRGTLIQNPCKTCHGAGRVEEDKVLSIKVPAGVDTGDRIRLAGEGEAGPAGTPPGDLYVEVRVREHAIFQRDGDDLHCEVPIRISQAALGDTVRVATLGGEAEIRIPAETQTGKLFRLRGKGVRSVRSRSEGDLYCRVVVETPVNLTADQRELLQQFEATFTGEDARKHSPKSATFIDGVKGFWDRMTS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXB_TOLAT
Sequence: MKIVVDENMPLAEALFAEFGEVVRVPGRTMTAEQLADADILLVRSVTKVNAALLSQATNLKFVGTATIGTDHIDKAVLAEKGINFTSAPGCNKVSVGEYIISALLVMAEKYQFSLSGLSLGVIGAGNTGTAVAERASALGIEVKLCDPLKEQAGDPRSFVSYDEALQCDLISFHVPLSREGEHATFHLLDKKYIQALRSEQILLNASRGEVWDNQAMLLRQQSAEPLLLVMDVWENEPDILHELVPYTDIATPHIAGYSLEGKYRGTYMLYEAFCQQFGYTVTKQLKQLLPVADINALTLNANTDEVVLKKLIHLVYDVRRDDARFRHQIGLPGRFDEMRKKYPERREWSSVTISSEQNNDELVKLGFSVSGN
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: E4PD_SALCH
Sequence: MTVRIAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGMAHLLKYDTSHGRFAWEVRHEREQLFVGDDVIRILHERTLADLPWRELGVDVVLDCTGVYGNREHGEAHIAAGAKKVLFSHPGSNDLDATVVFGVNQNQLRAEHRIVSNASCTTNCIIPVIKLLDDAYGIESGTVTTIHSAMNDQQVIDAYHSDLRRTRAASQSIIPVDTKLAAGITRIFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKASEVNQLLQKAAQGAFHGIVDYTESPLVSIDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMAAVGFRLDASASTKL
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRAR_STAS1
Sequence: MDILLVEDDMTLFKELSEELEQWDFNVNGIDDFNDVMTKFESVNPAIVIMDVKLPKYDGFYWTRKIREVSNTPILFLSSRDNPMDQVMSMELGADDYVQKPFNTNVLIAKLQAIYRRVYQFSLDEKRVLSWQDAILDLSKDSINKEDHQIYLSKTEMIILEMLVKKQNQIVTRDTLITALWDDEAFVSDNTLTVNVNRLRKKLADIDMNDAIETKIGKGYMAHG
What is the function of this protein?
Member of the two-component regulatory system GraR/GraS involved in resistance against cationic antimicrobial peptides (CAMPs).
What are the official names of this protein?
Response regulator protein GraR, Glycopeptide resistance-associated protein R.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE1_CHESB
Sequence: MTVTVRFAPSPTGQIHIGNARTALFNWLFARRAGGSFVLRFDDTDVERSRREYADQIEIDLAWLGIKPDLTVRQSERFGLYNQAVEKLKEAGRLYPCYETAEELELRRKIRLSRRLPPIYGREALKLTEEQKAAYEAEGRKPHWRFLLPNFDSDPFSTGRTEIHWDDVIRGPQTVDLASMSDPVLVREDGTFLYTLPSVVDDIDLGITHVIRGDDHVTNTGAQIALFEALGAKAPCFGHHNLLTTVTGEGLSKRTGALSIASLRKAGIEPMAVASLAVLIGTSEAVTAYRDMEELAAHFEPASSSKSSAKFDPAELEALSRSLIQAMPFEAAAPRLAAMGVEGSIAEPFWNAVRGNIDKLSEAAEWWHIVMKGPEPTEFTEDDRNFVNEAFDLLPPEPWDRETWRSWTEKVKEKTGRKGKALFRPLRLALTGRESGPELADLLPLLGRERTLARQP
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COFC_HALMD
Sequence: MRVVVPFSATEPKTRLAPVLDADERRAFARVMLADVLDALDTVGVDPTVLATEAIDLDRPVTVDDRPLDAAINGLLAASDEPVAVVMADLALATPDALDRLFAAEGDVVLAPGRGGGTNAFVARHPDFRVDYHDASIRDHRRIARDAGGTVTEIDSYRLSTDVDEPADLAEVLLHGEGRAADWLRGAGVQLTVADGRTTVERP
What is the function of this protein?
Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP.  It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
What are the official names of this protein?
2-phospho-L-lactate guanylyltransferase, LP guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CofC family.
Protein: RNC_ACTPJ
Sequence: MQLERLQKKLGYQFTNLDYLLQALTHRSAGAKNNERLEFLGDSILNFAIGKALFEKFPKANEGELSRMRATLVREQTLAILARKFGLGEYMKLGAGELKSGGYRRESILSDCVEAIIAAIYLDAGMDKAIAQVHLWYQDLLAEMKPGDAQKDPKTRLQEFLQGRKLPLPTYEVLNIKGEAHNQTFKVTCKIEMLEEIFIGIGTSRRKAEQNAAEQVLAKLTTK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YACG_PSEAB
Sequence: MSQPLTVECPTCGAPVEWKSDNKYRPFCSDRCKLIDLGAWAAEEHAIPGDTLEDDIFSADLPPREH
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: HBSAG_HBVA3
Sequence: MGGWSSKPRKGMGTNLSVPNPLGFFPDHQLDPAFGANSNNPDWDFNPVKDDWPAANQVGVGAFGPRLTPPHGGILGWSPQAQGILTTVSTIPPPASTNRQSGRQPTPISPPLRDSHPQAMQWNSTAFHQTLQDPRVRGLYLPAGGSSSGTVNPAPNIASHISSISARTGDPVTNMENITSGFLGPLLVLQAGFFLLTRILTIPQSLDSWWTSLNFLGGSPVCLGQNSQSPTSNHSPTSCPPICPGYRWMCLRRFIIFLFILLLCLIFLLVLLDYQGMLPVCPLIPGSTTTSTGPCKTCTTPAQGNSMFPSCCCTKPTDGNCTCIPIPSSWAFAKYLWEWASVRFSWLSLLVPFVQWFVGLSPTVWLSAIWMMWYWGPSLYSIVSPFIPLLPIFFCLWVYI
What is the function of this protein?
The middle envelope protein plays an important role in the budding of the virion.  It is involved in the induction of budding in a nucleocapsid independent way.  In this process the majority of envelope proteins bud to form subviral lipoprotein particles of 22 nm of diameter that do not contain a nucleocapsid.
What are the official names of this protein?
Large envelope protein, L glycoprotein, L-HBsAg, LHB, Large S protein, Large surface protein, Major surface antigen.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus major surface antigen family.
What are the subcellular locations of this protein?
Virion membrane.
Protein: PHFS_DESVH
Sequence: MQIASITRRGFLKVACVTTGAALIGIRMTGKAVAAVKQIKDYMLDRINGVYGADAKFPVRASQDNTQVKALYKSYLEKPLGHKSHDLLHTHWFDKSKGVKELTTAGKLPNPRASEFEGPYPYE
What is the function of this protein?
May be involved in hydrogen uptake for the reduction of sulfate to hydrogen sulfide in an electron transport chain.  Cytochrome c3 is likely to be the physiological electron carrier for the enzyme.
What are the official names of this protein?
Periplasmic [Fe] hydrogenase small subunit, Fe hydrogenlyase small chain.
What are the subcellular locations of this protein?
Periplasm.
Protein: YRY5_CAEEL
Sequence: MLCAKNKKDPKPPPASFSETSKVQNVQNTQPKPAAPSQMSIDESHSKNQKLPSAEKSVEECKKPVSPEKKKSPIKVLSEKKLKSKKKEEDKEPDEKVEKDVKKEVKADNNEPLVKNLKIAKKEQEEENPKTDLESHKDEAEAKKKESRRQKKMRNKNSKEGSVEKMEKSEKAY
What are the official names of this protein?
Uncharacterized protein T15H9.5.
Protein: CHSE1_MYCTU
Sequence: MDFDPTAEQQAVADVVTSVLERDISWEALVCGGVTALPVPERLGGDGVGLFEVGALLTEVGRHGAVTPALATLGLGVVPLLELASAEQQDRFLAGVAKGGVLTAALNEPGAALPDRPATSFVGGRLSGTKVGVGYAEQADWMLVTADNAVVVVSPTADGVRMVRTPTSNGSDEYVMTMDGVAVADCDILADVAAHRVNQLALAVMGAYADGLVAGALRLTADYVANRKQFGKPLSTFQTVAAQLAEVYIASRTIDLVAKSVIWRLAEDLDAGDDLGVLGYWVTSQAPPAMQICHHLHGGMGMDVTYPMHRYYSTIKDLTRLLGGPSHRLELLGARCSLT
What is the function of this protein?
Involved in the third cycle of side chain dehydrogenation in the beta-oxidation of cholesterol catabolism (PubMed:26161441).  May play an important role for the initial macrophage invasion, possibly in response to the acidification of phagosome (PubMed:18486437).  It contributes partly to the virulence by increasing the efficiency of beta-oxidation (PubMed:18486437, PubMed:22045806).  Catalyzes the dehydrogenation of 2'-propanoyl-CoA ester side chains of 3-oxo-4-pregnene-20-carboxyl-CoA (3-OPC-CoA) to yield 3-oxo-4,17-pregnadiene-20-carboxyl-CoA (3-OPDC-CoA).  Also able to dehydrogenate steroyl-CoA such as 3-oxo-chol-4-en-24-oyl-CoA (3-OCO-CoA), 1beta-(2'-propanoyl-CoA)-3a-alpha-H-7a-beta-methylhexahydro-4-indanone (indanone-CoA ester), hexahydroindanone and pregenenone (PubMed:22045806, PubMed:23560677, PubMed:26161441).
What are the official names of this protein?
Acyl-CoA dehydrogenase FadE28, ACAD, 3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA dehydrogenase alpha subunit, 3-oxo-4-pregnene-20-carboxyl-CoA dehydrogenase alpha subunit.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
Protein: MSRB_CAUVN
Sequence: MTDAATLSTAGFDLTPPTEAERERLEANLTAEEARVLLHHGTEAPFCGGLLGEKSPGVYGCRLCGLPLFKHETKFESGTGWPSFYAPFAEDHVVGVRDTSYGMVRIETRCARCDSHQGHVFPDGPAPTRLRYCINSVSLQFVKAGAPLPDPLHRGDKIT
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: Y1532_YERPN
Sequence: MAGHSKWANTKHRKAAQDAKRGKIFTKIIRELVTAARLGGGDPGANPRLRAAIDKALSNNMTRDTLNRAIARGVGGDEDNNMETIIYEGYGPGGTAVMVECLSDNRNRTVSEVRHAFTKTGGNLGTDGSVSYLFTKKGVISYAPGLEEDTVMDAALEAGADDIVVYDDGAIDVFTAWESLGAVKDALDATGLVAEGAEVSLIPSTKAELDAETAPKLLRLIDMLEDSDDVQEVYHNGEISDEVAATL
What are the official names of this protein?
Probable transcriptional regulatory protein YPN_1532.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_PROM2
Sequence: MSQTSLKKERDPSILILDFGSQYSELIARRIRETNVFSLVVSNCISIKEINNINPKGIILSGGPNSVYEQNAPKCDEKIFNLGIPILGICYGMQLMVKELGGSVIPATKKAEYGRAPINIDQESDLLSDVQDKSIMWMSHGDSIKCLPVGFNKIAHTENTLHAAISNDLKKLFGVQFHPEVIHSEYGMTVIKNFVYKISCCAADWTTETYIEETIPRIREQVGNKKVLLALSGGVDSSTLAFLLNKAIGNQLTCMFIDQGFMRKGEPEFLMNFFDKKFHIKVEYINARKRFISKLKGITEPEQKRKIIGEEFIRVFEEESNRLGPFQYLAQGTLYPDVIESAGTNIDPKTGERIAVKIKSHHNVGGLPKDLQFKLVEPLRKLFKDEVRQVGAALGLPAEIIKRHPFPGPGLAIRILGEVNNEKLDCLRDADWIVRDEIKKAGLYNEIWQAFAVLLPVKTVGVMGDKRTYAWPIVLRCVSSEDGMTADWSKIPFKILERIANRIVNEVISVNRVVYDITSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: YN84_SCHPO
Sequence: MISNSSIEDRINKNEAYIAKFFEIFSKNDKIRFHGVSLDRKALDSFMVRNNFKKRFVSGINLPILIRLHFYKKLFTILWLTVRTVALLSHARNIQCLIQESDGDAKDVARSIYITTAEFRNYLLTEKGFYVTTRSISHFRAILDSIRYPFGKDHASKNMELLPITYDLSFCTVFHGYLTSILEAYEFFRGVFKKYKAPLSSNFIAIGKTTDESNFSQLHHYFQKFDERIRRILHLISQELDGYCRIAKQ
What are the official names of this protein?
Uncharacterized protein P35G2.04c.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: TGT_CYAP4
Sequence: MNDSLQAIPNQPFSFFTQASCSHTQARAGQFFTPHGVVETPRFMPVGTLANIKTVTPEQLRGTGAQMILANTYHLHLQPGEGIVAAAGGLHRFMGWTGPILTDSGGFQVFSLSELRSIAEAGVTFRSPRDGEEIYLSPEKAIAIQNQLGADVIMAFDECAPYPADRSTVTEAVERTTRWLERCCKAHDRVEDQALFGIIQGGTYGDLRQQSARSLVEFDLPGYAIGGVSVGEPPELIEKIVKFTTPLLPEHKPRYLMGVGTYREMVQAIAAGIDLFDCVIPTRLARHGNALVRGERWNLKNSRFREDFQPLDQSCACYTCQNFSRAYLSHLLRARELLAYTLLSIHNITELISFTQKIRQAILHDRFSSEFASWLTSPSPS
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.