PharMolix/UniProtQA huggingface dataset:
Protein: YICR_ECOLU
Sequence: MKNNAQLLMPREKMLKFGISALTDVELLALFLRTGTRGKDVLTLAKEMLENFGSLYGLLTSEYEQFSGVHGIGVAKFAQLKGIAELARRYYNVRMREESPLLSPEMTREFLQSQLTGEEREIFMVIFLDSQHRVITHSRLFSGTLNHVEVHPREIIREAIKINASALILAHNHPSGCAEPSKADKLITERIIKSCQFMDLRVLDHIVIGRGEYVSFAERGWI
What are the official names of this protein?
UPF0758 protein YicR.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family. YicR subfamily.
Protein: PHNX_BACC1
Sequence: MKIEAVIFDWAGTTVDYGCFAPLEVFMEIFHKRGVVITAEEARKPMGLLKIDHVRALTEMPRIASEWNRVFGQLPTETDIQEMYEEFEEILFTILPRYASPIHGVKEVIASLRERGIKIGSTTGYTREMMDIVAKEAALQGYKPDFLVTPDDVPAGRPYPWMCYKNAMELGVYPMNHMIKIGDTVSDMKEGRNAGMWTVGVILGSSELGLSEEEVENMDPVELREKIEVVRNRFVENGAHFTIETMQELETVMEHIEKQQLIIS
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
Phosphonoacetaldehyde hydrolase, Phosphonatase, Phosphonoacetaldehyde phosphonohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PhnX family.
Protein: C71D9_SOYBN
Sequence: MDLQLLYFTSIFSIFIFMFMTHKIVTKKSNSTPSLPPGPWKLPIIGNMHNLVGSPLPHHRLRDLSAKYGSLMHLKLGEVSTIVVSSPEYAKEVMKTHDHIFASRPYVLAAEIMDYDFKGVAFTPYGDYWRQLRKIFALELLSSKRVQSFQPIREEVLTSFIKRMATIEGSQVNVTKEVISTVFTITARTALGSKSRHHQKLISVVTEAAKISGGFDLGDLYPSVKFLQHMSGLKPKLEKLHQQADQIMQNIINEHREAKSSATGDQGEEEVLLDVLLKKEFGLSDESIKAVIWDIFGGGSDTSSATITWAMAEMIKNPRTMEKVQTEVRRVFDKEGRPNGSGTENLKYLKSVVSETLRLHPPAPLLLPRECGQACEINGYHIPAKSRVIVNAWAIGRDPRLWTEAERFYPERFIERSIEYKSNSFEFIPFGAGRRMCPGLTFGLSNVEYVLAMLMYHFDWKLPKGTKNEDLGMTEIFGITVARKDDLYLIPKTVHN
What are the official names of this protein?
Cytochrome P450 71D9, Cytochrome P450 CP3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: KAD_NEIAN
Sequence: FITAAFGIPQISTGDMLRAAIKAGTPLGLEAKKIIDEGGLVRDDIIIGMVKERIAQDDCKNGFLFDGFPRTLAQAEAMVEAGVDLDAVVEIDVPDSVIVDRMSGRRVHLASGRTYHIAYNPPKVEGKDDVTGEDLIQRDDDKEETVKKRLDVYHGQTEVLVGFYSKLTGEHAPK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BEA2_GIBIN
Sequence: MTSQEHPNWLTALLVDTRPPPKLFAWSPANIQPKLDEGIDMGSSNSDEEYDNDACVCQSTDSDQRIYIIGPGNIGRLYATHMARHPNALPITLVVHRKELLSQWVACEGVGLADITSGKLFLNKGFTVEWWTETRPPYGPVKEVADGKKLHNVFISTKAEAGLAEADRIRRYLGRCSSVVFAQNGVCKLWPPHGPLYISHRYPSGDTPTFSACVVSHGVASAGPFLSVHAAPADAYIGPVFWASDPESPWRHPSDDFFIRHIATTPHVNTKQVSSGEIWLLQLEKLVMNAAINPLTALLRCKTGELFTSYGSDDPLALVIDKLLWQTSAVIQGLVDHKTSHSVITSYAEHMSQPGTSCSVPKVRKKLMERFSQPILKAKLGWEEDRDTGL
What is the function of this protein?
Ketoisovalerate reductase; part of the gene cluster that mediates the biosynthesis of beauvericin (BEA), a non-ribosomal cyclic hexadepsipeptide that shows antibiotic, antifungal, insecticidal, and cancer cell antiproliferative and antihaptotactic activity (PubMed:23832252, PubMed:22916830).  Ketoisovalerate reductase BEA2 catalyzes the NADPH-specific reduction of ketoisovaleric acid to hydroxyisovalerate, a precursor for beauvericin biosynthesis (PubMed:23832252, PubMed:22916830).  The nonribosomal cyclodepsipeptide synthetase BEA1 then catalyzes the formation of beauvericin via condensation and cyclization of 3 dipeptidol monomers, each composed of one unit of hydroxyisovalerate and one unit of N-methyl-phenylalanine (By similarity).
What are the official names of this protein?
Ketoisovalerate reductase BEA2, KIVR.
What is the protein family that this protein belongs to?
Belongs to the ketopantoate reductase family.
Protein: OX2G_MOUSE
Sequence: MGSLVFRRPFCHLSTYSLIWGMAAVALSTAQVEVVTQDERKALHTTASLRCSLKTSQEPLIVTWQKKKAVSPENMVTYSKTHGVVIQPAYKDRINVTELGLWNSSITFWNTTLEDEGCYMCLFNTFGSQKVSGTACLTLYVQPIVHLHYNYFEDHLNITCSATARPAPAISWKGTGTGIENSTESHFHSNGTTSVTSILRVKDPKTQVGKEVICQVLYLGNVIDYKQSLDKGFWFSVPLLLSIVSLVILLVLISILLYWKRHRNQERGESSQGMQRMK
What is the function of this protein?
Costimulates T-cell proliferation.  May regulate myeloid cell activity in a variety of tissues (By similarity).
What are the official names of this protein?
OX-2 membrane glycoprotein, MRC OX-2 antigen.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RL23_HELPJ
Sequence: MADIMDIKSILYTEKSLGLQEKGVLVVQTAQNVTKNQLKEVFKTYFGFEPLKINSLKQEGKVKRFRGKLGQRKSFKKFYVKVPEGASIAALGA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: SURE_PARMW
Sequence: MRVLISNDDGVFAEGIRTLAAAAVARGHDVTVVCPDQERSATGHGLTLQTPIRAERADELFVPGVTAWACSGTPADCMKLALFELVKDKPDLVLSGINHGPNLGTDVFCSGTVAAAMEGTLEGIPSMAISSACFQWRQFQAGAELAVEVAEQALADQWPENLLLNLNIPPCNRDAMGPLRWTRLSIRRYDEQFSSRVDPRGRAYYWLAGEVVNDLESAGEGPRDWPSDVAQIHANSPSLTPIQPDLFWRGSLSGLPQLKLKDQLVR
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BDSG_ANEVI
Sequence: AAPCSCPGKPGRGDLWIFRGTCPGGYGYTSNCYKWPNICCYPH
What is the function of this protein?
Blocks Kv3 voltage-gated potassium channels (By similarity).  Reduces blood pressure (By similarity).
What are the official names of this protein?
Kappa-actitoxin-Avd4p, Kappa-AITX-Avd4p, Blood depressing substance 16, BDS-16.
What is the protein family that this protein belongs to?
Belongs to the sea anemone type 3 (BDS) potassium channel toxin family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: KITH_MOUSE
Sequence: MSYINLPTVLPSSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTRYSNSFSTHDRNTMDALPACMLRDVTQESLGVAVIGIDEGQFFPDIVDFCEMMANEGKTVIVAALDGTFQRKAFGSILNLVPLAESVVKLTAVCMECFREAAYTKRLGLEKEVEVIGGADKYHSVCRLCYFKKSSAQTAGSDNKNCLVLGQPGEALVVRKLFASQQVLQYNSAN
What is the function of this protein?
Cell-cycle-regulated enzyme of importance in nucleotide metabolism.  Catalyzes the first enzymatic step in the salvage pathway converting thymidine into thymidine monophosphate.  Transcriptional regulation limits expression to the S phase of the cell cycle and transient expression coincides with the oscillation in the intracellular dTTP concentration.
What are the official names of this protein?
Thymidine kinase, cytosolic.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ULP4_CAEEL
Sequence: MEVSTSYCTPAVNFKYGSFQDSDVSMREDDLFRMGSYNSQGYYADGTHLDGSIGEEDETSSGSNDQHMDFEEDDFDMESSMTEDLVDEDEEEEDEEDNDEWTNQKRTDNQNSVAYYAAMEMLRIRFPFQSIAIRISDFCCLQEKDLLNDTMIDFYLNHIVEHVLPDSNGSNVTVLPSIFWHNLSLRQHAFDSEDEKMMSDEQKMDLKFGDLHDFVADFDLQDFDYIVVPVNEWEHWSLAVICHPFTAQARTVIFDSQLTADLNNLQNMATLIESFMKYSYEKRTGNAMPFPLPCILPQRMPQQTNNFDCGIFIAEFARRFLLSPPKDLDNFDFAREYPDFSTATKRTEMQRVVLSLSTNRARWRPLVELLNGYSTAAPHRAL
What is the function of this protein?
Protease required for deconjugation of smo-1 conjugates from target proteins which is necessary for cell cycle progression (PubMed:25475837) (Probable).  Required for respiration and the maintenance of normal mitochondrial homeostasis (PubMed:25187565).  In response to mitochondrial stress, required for the removal of smo-1 conjugates from the transcription factor dve-1, which promotes the translocation of dve-1 from the cytosol to the nucleus to initiate the mitochondrial unfolded protein response (PubMed:30642431).  Furthermore, removes the smo-1 conjugates from the transcription factor atfs-1 to promote its stability and activate the mitochondrial unfolded protein response (PubMed:30642431).  Also plays a role in promoting mitochondrial unfolded protein response-mediated innate immunity following infection with P. aeruginosa (PubMed:30642431).
What are the official names of this protein?
Ubiquitin-like protease 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase C48 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm. Mitochondrion matrix. Note=Localizes around the metaphase plate and the pericentriolar region and in the surroundings of the central spindle (PubMed:25475837). Translocates from cytoplasm to mitochondrion at late developmental stages (PubMed:25187565).
Protein: SECF_RHOCB
Sequence: MAFRLKLVPEKTNFDFFRWQWATFGAAIVMMIASVILPLVIGLNFGIDFKGGTTIRTESTTAIDVGVYRAALEPLELGDVIISEVRDPSFREDQHVAMIRIQMQEDGQGAEGQGAQGQELVNKVETALTAVDPALKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVLLTVGLFAVLQLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVNETLSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIVLFIGLDRNKEKKDPSDKFFSNGAQDGAP
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecF.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RHLB_SODGM
Sequence: MSKTHLTEKKFSDFALYPPIVEVLDSKGFNNCTPIQALTLPTTLAGKDVAGQAQTGTGKTLAFLTATFHHLLTHPAAEGRQTNQPRALIMAPTRELAVQIHSDAEPLAQATGLKMGLAYGGDGYDKQLKVLEAGVDILVGTTGRLIDYTKQNYVNMSAIQVVVLDEADRMFDLGFIKDIRWLFRRMPAAAGRLNMLFSATLSYRVRELAFEHMNNAEYVEVEPLQKTGHRIQEELFYPSNEEKMRLLQTLIEEEWPDRCIIFANTKHRCEDIWGHLAADGHRVGLLTGDVSQKRRLRILEKFTQGALDILVATDVAARGLHIPSVTHVFNYDLPDDCEDYVHRIGRTGRAGESGCSISLACEEYALNLTAIESYIGHQIPVSKYNSDALLTDLPAPKRLTRRRSGAPRHNRKRPG
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COMPL_BPT4
Sequence: MFGYFYNSSFRRYATLMGDLFSNIQIKRQLESGDKFIRVPITYASKEHFMMKLNKWTSINSQEDVAKVETILPRINLHLVDFSYNAPFKTNILNQNLLQKGATSVVSQYNPSPIKMIYELSIFTRYEDDMFQIVEQILPYFQPHFNTTMYEQFGNDIPFKRDIKIVLMSAAIDEAIDGDNLSRRRIEWSLTFEVNGWMYPPVDDAEGLIRTTYTDFHANTRDLPDGEGVFESVDSEVVPRDIDPEDWDGTVKQTFTSNVNRPTPPEPPGPRT
What is the function of this protein?
Stabilizes the tail sheath structure and acts as a connector between the end of tail and the portal vertex of the capsid.
What are the official names of this protein?
Tail completion protein gp15, Gene product 15, gp15, Tail connector protein 15, Tail terminator protein.
What are the subcellular locations of this protein?
Virion.
Protein: UGPC_RUEPO
Sequence: MASITLDNLVKAYGDTEVLHHVAGQIEDGEFIVIVGPSGCGKSTLLRMVAGLETVTAGQISIGDRVVNQLEPADRDIAMVFQNYALYPHMSVRENMAYGLKIRKISKDEIARRVEEAADILELRPYLDRKPRQLSGGQRQRVAMGRAIVRNPQVFLFDEPLSNLDAKLRVQMRLEIRKLQQRLGVTSIYVTHDQVEAMTLGDRLMVLNGGYVEQFGTPIELYDRPATTFVAGFIGSPAMNFLPATAAEGSVTLANGARIAGSGTAHGTVTLGLRPEHLLPDEGGPVRVRVELVEQLGANSLLHGQLEGTDTEMVVSMPGHMSAAADAVMAFTPTADSLHLFDPETGKRIAE
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
sn-glycerol-3-phosphate import ATP-binding protein UgpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LRR1_ARATH
Sequence: MASRNYRWELFAASLTLTLALIHLVEANSEGDALYALRRSLTDPDHVLQSWDPTLVNPCTWFHVTCNQDNRVTRVDLGNSNLSGHLAPELGKLEHLQYLELYKNNIQGTIPSELGNLKNLISLDLYNNNLTGIVPTSLGKLKSLVFLRLNDNRLTGPIPRALTAIPSLKVVDVSSNDLCGTIPTNGPFAHIPLQNFENNPRLEGPELLGLASYDTNCT
What is the function of this protein?
Involved in plant defense response.
What are the official names of this protein?
Leucine-rich repeat protein 1, AtLRR1.
Protein: ARNF_ECOLI
Sequence: MGLMWGLFSVIIASVAQLSLGFAASHLPPMTHLWDFIAALLAFGLDARILLLGLLGYLLSVFCWYKTLHKLALSKAYALLSMSYVLVWIASMVLPGWEGTFSLKALLGVACIMSGLMLIFLPTTKQRY
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF, L-Ara4N-phosphoundecaprenol flippase subunit ArnF, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnF.
What is the protein family that this protein belongs to?
Belongs to the ArnF family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IMSP2_RUDPH
Sequence: MHQSSLGVLVLFSLIYLCISVHVPFDLNGWKALRLDNNRVQDSTNLAVEHLAGQLKQPITAFKLEENIPNWDLYRVSFIGTYFKGEEYECHSDVVWIFNPFNVTVFNTGCLPTSQLNFKY
What are the official names of this protein?
Insoluble matrix shell protein 2, IMSP2.
What are the subcellular locations of this protein?
Secreted.
Protein: EFTS_DELAS
Sequence: MAAITASMVAELRAKTDAPMMECKKALTEAEGDLVKAEELLRVKLGTKAGKAASRVTAEGVIAAFINGNQGAMIEVNSETDFVSKNDSFIAMANAAAKLVAEQNPADVAALSALAYEQDGFGPTLEDVRKGLIGKIGENMSFRRFKRFDGTSLASYLHGSRIGVVVEFDGDATAAKDVAMHVAAMKPVSVTSADVPAELIEKERTVAAAKAAESGKPAEIVAKMVEGSVQKYLKEVSLADQVFVKAADGKQTVAQMLKAANTNVKGFTLYVVGEGIEKKVDDFAAEVAAQVAAAKAGA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_THESQ
Sequence: MPGQKIRIKLKAYDHELLDESAKKIVEVAKSTNSKVSGPIPLPTERTLYCVLRSPMKHKDSREHFEKRVHKRLIDIIDPSPKTIDALMRINLPAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: NUOB_CLOB8
Sequence: MEVNFKQDKEIQEQIEKNIILTKLDDTLNYFRAHSFWPLTFGLACCAIEMMAAGGARYDIARFGYEVFRASPRQADLMIVAGTITEKMAPIVKKIYDQMPEPKWVIAMGSCATSGGPFVDSYNVVPGADTFLPVDVYIPGCPPRPEALIHGLLTLKEKIIHPKEVGRSE
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y104_MYCPN
Sequence: MVELDGKFATKADLKRVEDKVDVLFELQKTQGEQIKVQGKQIEQLTETVQKQGEQIKELQVQVKAQGEEIKEIKVEQKAQGQTLQLILKALEGINKRLDNLESK
What are the official names of this protein?
UPF0134 protein MPN_104.
What is the protein family that this protein belongs to?
Belongs to the UPF0134 family.
Protein: TSAC_CELJU
Sequence: MIDWSLNPRVNYAANMMRQGGVIAYPTEAVWGLGCNPFDEDAVADLLALKQRPVEKGVILIAANLQQIEPFIDHLDDLQRQRLKNTWPGPVTWLVPNNGLAPHWITGAFPSVALRVTDHPVAAGLCRAFGGPVVSTSCNPAGKPPARNIHEVRRYFGGQLDAVSSGLAGRRTNPSEIRDLLTGQVVRPS
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GGGPS_PYRHO
Sequence: MGELRIGKVEKYIHEKLEKKKLHFVLIDPDDTSPEVAGKLARVCEELGVDAIMVGGSTGAEGEVLDNVVRSIKDNSSLPVILFPGSHGGISRYADAIFFMSLLNSRNPFFITGAQALGAFTVKKFGIEPIPMAYIVVEPGETVGWVGDARPIPRHKPKLAAAYALAGQYLGMRLVYLEAGSGAPEPVPEEMVRVVKSVIDVPLIVGGGIKSGEQAKKLIKSGADIIVTGTAIEKAKSLEEARKRLEAIRNGVFV
What is the function of this protein?
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).  This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
Geranylgeranylglyceryl phosphate synthase, GGGP synthase, GGGPS, (S)-3-O-geranylgeranylglyceryl phosphate synthase, Phosphoglycerol geranylgeranyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_ECO45
Sequence: MKSLQALFGGTFDPVHYGHLKPVETLANLIGLTRVTIIPNNVPPHRPQPEANSMQRKHMLELAIADKPLFTLDERELKRNAPSYTAQTLKEWRQEQGPDVPLAFIIGQDSLLTFPTWYEYETILDNAHLIVCRRPGYPLEMAQPQYQQWLEDHLTHNPEDLHLQPAGKIYLAETPWFNISATIIRERLQNGESCEDLLPEPVLTYINQQGLYR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: NHAA1_PSEPK
Sequence: MEGLQPVRSLFTRFFQLEAASGLLLIAAAVLALIINNSPLSYLYGGLLEVPVAVQVGALNIAKPLLLWINDGLMALFFLLIGLEVKREVVDGHLSKPSQVILPATAAVGGMVVPALIYWFINRDNPAAVAGWAIPTATDIAFALGVLALLGKRVPVSLKLFLMTLAIIDDLGAIIVIALFYSGTLSSVSLLLAAACLLVLVAMNRLGVIKLGPYMIVGLILWVCVLKSGVHATLAGVALAFCIPLRTRNAESSPLLALEHALHPWVAYAILPIFAFANAGVSLAGMTVDSFTHPVPMGITIGLLLGKTVGVFGLTWVAVKLRLAALPAGAGWGQILGVAILCGIGFTMSLFVGSLAFAPGSSEYAGMDRMGILTGSFFAAVIGYAVTAMASRKTSIA
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 1, Sodium/proton antiporter NhaA 1.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSBN_PROMS
Sequence: MQTLSSAPDPAVSIAVTILALLLALTGFGLWTAFGPKAAKLTDPWDDHDD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: DIT22_ARATH
Sequence: MESLALRSISLSASYLSLHRSSSKSFALLPPSISVHTSPTLRSLSISSPRFTLRATASSLPEEQNKPQPPPPSPPQPQGAKLIPLAISVSIGLIVRFLIPRPEQVTSQGWQLLSIFLFTISGLVLGPLPVGAWAFIGLTASIVTKTLPFSTAFAAFTNELIWLIAISFFFARGFIKTGLGDRIATYFVKWLGKSTLGLSYGLAFCETLMGLIMPSTMARAGGVFLPVIKSLAISAGSYPGDPSSRKLGSFLIQTQLQCSGASGAILLTSAAQNLLCLKLAREVGVVISNPWITWFKVASVPAFVSLLCTPLIIYKLYPPELKHTPEAPAAAAKKLERLGPITKNEWIMLGAMAFTVSLWVFGEAIGIASVVSAMIGLSTLLLLGVINWDDCLSDKSAWDSLTWFAVLIGMAGQLTNLGVVAWMSDCVAKLLQSLSLTWPASFIILQACYLLIHYLFASQTGHAGALYPPFLAMQIAAGVPGVLAALCLAFNNNLSGALAHYSGGPAALYYGAGYVDLRDMFRVGFVMALVQAIIWGGVGSFWWKFLGLY
What is the function of this protein?
May be involved in the transport of dicarboxylate compounds.
What are the official names of this protein?
Dicarboxylate transporter 2.2, chloroplastic, AtpDCT2.
What is the protein family that this protein belongs to?
Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: IFNG_CANLF
Sequence: MNYTSYILAFQLCVILCSSGCNCQAMFFKEIENLKEYFNASNPDVSDGGSLFVDILKKWREESDKTIIQSQIVSFYLKLFDNFKDNQIIQRSMDTIKEDMLGKFLNSSTSKREDFLKLIQIPVNDLQVQRKAINELIKVMNDLSPRSNLRKRKRSQNLFRGRRASK
What is the function of this protein?
Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation.  Primarily signals through the JAK-STAT pathway after interaction with its receptor IFNGR1 to affect gene regulation.  Upon IFNG binding, IFNGR1 intracellular domain opens out to allow association of downstream signaling components JAK2, JAK1 and STAT1, leading to STAT1 activation, nuclear translocation and transcription of IFNG-regulated genes.  Many of the induced genes are transcription factors such as IRF1 that are able to further drive regulation of a next wave of transcription.  Plays a role in class I antigen presentation pathway by inducing a replacement of catalytic proteasome subunits with immunoproteasome subunits.  In turn, increases the quantity, quality, and repertoire of peptides for class I MHC loading.  Increases the efficiency of peptide generation also by inducing the expression of activator PA28 that associates with the proteasome and alters its proteolytic cleavage preference.  Up-regulates as well MHC II complexes on the cell surface by promoting expression of several key molecules such as cathepsins B/CTSB, H/CTSH, and L/CTSL (By similarity).  Participates in the regulation of hematopoietic stem cells during development and under homeostatic conditions by affecting their development, quiescence, and differentiation (By similarity).
What are the official names of this protein?
Interferon gamma, IFN-gamma.
What is the protein family that this protein belongs to?
Belongs to the type II (or gamma) interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: RHG06_TAKRU
Sequence: GDFTWNSLSGRSVRLAPVDIQSLSELERARLQEVAFTRLHQDYDLGCQITMPK
What is the function of this protein?
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.  Could regulate the interactions of signaling molecules with the actin cytoskeleton.  Promotes continuous elongation of cytoplasmic processes during cell motility and simultaneous retraction of the cell body changing the cell morphology (By similarity).
What are the official names of this protein?
Rho GTPase-activating protein 6, Rho-type GTPase-activating protein 6, Rho-type GTPase-activating protein RhoGAPX-1.
What are the subcellular locations of this protein?
Cytoplasm.