PharMolix/UniProtQA huggingface dataset:
Protein: HGD_PSESM
Sequence: MAIHSSFEALAYQSGFANQFSSEALPGALPMGQNSPQKHPLGLYAEQFSGTAFTVARNEARRTWLYRIKPSAAHPRYQRMDRQITGREQGPINPNRLRWNAFDIPAEPVDFIDGLIALASTSAADQAEGVSVYVYAANTSMQRAFFSADGEWLIVPQQGRLRIITEMGVLDIGPLEIAVLPRGLKFSVQLLDGSARGYLCENHGGVLRLPELGPIGSNGLANPRDFLTPVAWFEERDEPVQLVQKFLGELWTTQLQHSPFDVVGWHGNNVPYTYDLRRFNTIGTVSYDHPDPSIFTVLTSPGAVHGQANIDFVIFPPRWMVAENTFRPPWFHRNLMNEFMGLIDGAYDAKAEGFMPGGSSLHNCMSAHGPDNITAEKAIAADLKPHKIENTMAFMFETGKVLRPSLHALACPQLQADYDACWNGMARTFNKESS
What is the function of this protein?
Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine.  Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, HGDO, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: YEJM_ECOLI
Sequence: MVTHRQRYREKVSQMVSWGHWFALFNILLSLVIGSRYLFIADWPTTLAGRIYSYVSIIGHFSFLVFATYLLILFPLTFIVGSQRLMRFLSVILATAGMTLLLIDSEVFTRFHLHLNPIVWQLVINPDENEMARDWQLMFISVPVILLLELVFATWSWQKLRSLTRRRRFARPLAAFLFIAFIASHVVYIWADANFYRPITMQRANLPLSYPMTARRFLEKHGLLDAQEYQRRLIEQGNPDAVSVQYPLSELRYRDMGTGQNVLLITVDGLNYSRFEKQMPALAGFAEQNISFTRHMSSGNTTDNGIFGLFYGISPSYMDGILSTRTPAALITALNQQGYQLGLFSSDGFTSPLYRQALLSDFSMPSVRTQSDEQTATQWINWLGRYAQEDNRWFSWVSFNGTNIDDSNQQAFARKYSRAAGNVDDQINRVLNALRDSGKLDNTVVIITAGRGIPLSEEEETFDWSHGHLQVPLVIHWPGTPAQRINALTDHTDLMTTLMQRLLHVSTPASEYSQGQDLFNPQRRHYWVTAADNDTLAITTPKKTLVLNNNGKYRTYNLRGERVKDEKPQLSLLLQVLTDEKRFIAN
What are the official names of this protein?
Inner membrane protein YejM.
What is the protein family that this protein belongs to?
To H.influenzae HI_0842.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ZN629_HUMAN
Sequence: MEPETALWGPDLQGPEQSPNDAHRGAESENEEESPRQESSGEEIIMGDPAQSPESKDSTEMSLERSSQDPSVPQNPPTPLGHSNPLDHQIPLDPPAPEVVPTPSDWTKACEASWQWGALTTWNSPPVVPANEPSLRELVQGRPAGAEKPYICNECGKSFSQWSKLLRHQRIHTGERPNTCSECGKSFTQSSHLVQHQRTHTGEKPYKCPDCGKCFSWSSNLVQHQRTHTGEKPYKCTECEKAFTQSTNLIKHQRSHTGEKPYKCGECRRAFYRSSDLIQHQATHTGEKPYKCPECGKRFGQNHNLLKHQKIHAGEKPYRCTECGKSFIQSSELTQHQRTHTGEKPYECLECGKSFGHSSTLIKHQRTHLREDPFKCPVCGKTFTLSATLLRHQRTHTGERPYKCPECGKSFSVSSNLINHQRIHRGERPYICADCGKSFIMSSTLIRHQRIHTGEKPYKCSDCGKSFIRSSHLIQHRRTHTGEKPYKCPECGKSFSQSSNLITHVRTHMDENLFVCSDCGKAFLEAHELEQHRVIHERGKTPARRAQGDSLLGLGDPSLLTPPPGAKPHKCLVCGKGFNDEGIFMQHQRIHIGENPYKNADGLIAHAAPKPPQLRSPRLPFRGNSYPGAAEGRAEAPGQPLKPPEGQEGFSQRRGLLSSKTYICSHCGESFLDRSVLLQHQLTHGNEKPFLFPDYRIGLGEGAGPSPFLSGKPFKCPECKQSFGLSSELLLHQKVHAGGKSSQKSPELGKSSSVLLEHLRSPLGARPYRCSDCRASFLDRVALTRHQETHTQEKPPNPEDPPPEAVTLSTDQEGEGETPTPTESSSHGEGQNPKTLVEEKPYLCPECGAGFTEVAALLLHRSCHPGVSL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 629, Zinc finger protein 65.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CHEY_YEREN
Sequence: MADKNLRFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALNKLRTGGFDFVVSDWNMPNMDGLDLLKTIRADGALGTLPVLMVTAEAKKENIIAAAQAGASGYVVKPFTAATLEEKLNKIFEKLGM
What is the function of this protein?
Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors.  In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation (By similarity).
What are the official names of this protein?
Chemotaxis protein CheY.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEF_CHRVO
Sequence: MNIHAATPEHSPLGKTVSYQDQYDPSLLFPIARQTKRDEIGVDEAALPFAGVDIWTGFELSWLNARGKPQIGIATFRIPAGSPRLIESKSFKLYLNSYNQTRMDGIDALAAQLARDLSAAAGAEVAVSIALPQAFAAERIAELAGECIDELDIAVDNYAPCPEILSADSTAIVSETLCSNLLKSNCLVTGQPDWGSVSIRYTGPKIDREALLRYLIGFRRHNEFHEQCVERIFVDVLRACAPTKLTVYARYTRRGGLDINPWRSNCDAAPTDNVRTARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CD1C2_CAVPO
Sequence: MLFLQFLFVDVVLGGSITENVVQENISLYLMQISSYANQSWTQNLGSAWLDQLQTHSWDSESGTIIFLHAWSRGNFSNEEVTDMQLLLRVHFAELTLDVHQQASQLQFKYPFDIQVRLGCELHSRETTKSFLHVAFNGLNFLSFQHKSCVPSPEGETRAQKACDILNTYEATKEIAYYVMNDICPRLLLSLLEAGKMDLQRQVRPEVWLSSSPNLEPGRLLLACHVSGFYPKPIWVMWMRGAQEQLETKQGDILPHADGTWYLRVTLNVVAEEAAGLSCRVRHSSLRDQDIILYWGHGLSVILIALAVIVPLVLLIVLVLLCKKRCTYQGIP
What is the function of this protein?
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
What are the official names of this protein?
T-cell surface glycoprotein CD1c2.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endosome membrane. Note=Subject to intracellular trafficking between the cell membrane and endosomes.
Protein: RSMI_RHILO
Sequence: MVGQTEIPARPLEPALYLVATPIGNLADITLRALETLAAADIVACEDTRVSRVLLDRYGIRRRTTAYHEHNAGEAGPKLIAALQGGQSVALISDAGTPLVSDPGYRLVGEAIDHGIRVVPIPGPSAPLAALTASGLPSDAFLFAGFLPVKVGQRLTRLEALKAVPATLIFFESPRRLAESLGAMVEALGGERKAAIGRELTKTFEEMRTGTLRALADHYAAADTPKGEIVVCVGPAEAKADEPADIDRLLLSLAAEMPASKAASEAAKMTGGQKQALYRRLLELKDTSGEGDGG
What is the function of this protein?
Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase I, 16S rRNA 2'-O-ribose C1402 methyltransferase, rRNA (cytidine-2'-O-)-methyltransferase RsmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7L_MYCTO
Sequence: MTQNSAENPFPVRAVAIRVAGWIDKLGAVWVEGQLAQITMRPDAKTVFMVLRDPAADMSLTVTCSRDLVLSAPVKLAEGVQVVVCGKPSFYTGRGTFSLRLSEIRAVGIGELLARIDRLRRLLDAEGLFDPRLKRPIPYLPNMIGLITGRASAAERDVTTVASARWPAARFAVRNVAVQGPNAVGQIVEALRELDRDPDVDVIVLARGGGSVEDLLPFSDETLCRAIAACRTPVVSAVGHEPDNPLCDLVVDLRAATPTDAAKKVVPDTAAEQRLIDDLRRRSAQALRNWVSREQRAVAQLRSRPVLADPMTMVSVRAEEVHRARSTLRRNLTLMVAAETERIGHLAARLATLGPAATLARGYAIVQTVAQTGPEGGSEPQVLRSVHDAPEGTKLRVRVADGALAAVSEGQTNGL
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCS_BORBU
Sequence: MKNINLILAWLVHIFTASGLIVGLYSIISIVNGNYSLLLKLTVIGLIIDGIDGTMARKLKVKELIPEIDGTLLDNITDYINYTFIPVIFFYLGEFIEEKYKVAICIGILLSSAYQFSRTDAKTNDNYFRGFPSLWNLFVILNIIFKMEQITNLITMSICIITSFIPIKFIYPSKTKELRKITIPITIISCLIFVVSIFSELSTTALKMAKTVLILYFAYLTLASIYLTYKTRNR
What is the function of this protein?
Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP.
What are the official names of this protein?
Phosphatidylcholine synthase, PC synthase, PCS, CDP-diglyceride-choline O-phosphatidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UPP_ECO27
Sequence: MKIVEVKHPLVKHKLGLMREQDISTKRFRELASEVGSLLTYEATADLETEKVTIEGWNGPVEIDQIKGKKITVVPILRAGLGMMDGVLENVPSARISVVGMYRNEETLEPVPYFQKLVSNIDERMALIVDPMLATGGSVIATIDLLKKAGCSSIKVLVLVAAPEGIAALEKAHPDVELYTASIDQGLNEHGYIIPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: HIS1_YEAST
Sequence: MDLVNHLTDRLLFAIPKKGRLYSKSVSILNGADITFHRSQRLDIALSTSLPVALVFLPAADIPTFVGEGKCDLGITGVDQVRESNVDVDLAIDLQFGNCKLQVQVPVNGEYKKPEQLIGKTIVTSFVKLAEKYFADLEGTTVEKMTTRIKFVSGSVEASCALGIGDAIVDLVESGETMRAAGLVDIATVLSTSAYLIESKNPKSDKSLIATIKSRIEGVMTAQRFVSCIYNAPEDKLPELLKVTPGRRAPTISKIDDEGWVAVSSMIERKTKGVVLDELKRLGASDIMVFEISNCRV
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of the enzymatic activity (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCST_HUMAN
Sequence: MQRAVSVVARLGFRLQAFPPALCRPLSCAQEVLRRTPLYDFHLAHGGKMVAFAGWSLPVQYRDSHTDSHLHTRQHCSLFDVSHMLQTKILGSDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGCWEKDLALMQDKVRELQNQGRDVGLEVLDNALLALQGPTAAQVLQAGVADDLRKLPFMTSAVMEVFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATAILKNPEVKLAGLAARDSLRLEAGLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMCEGAPMRAHSPILNMEGTKIGTVTSGCPSPSLKKNVAMGYVPCEYSRPGTMLLVEVRRKQQMAVVSKMPFVPTNYYTLK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, mitochondrial, Glycine cleavage system T protein, GCVT.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y003_OSHVF
Sequence: MNDEEEMNEEGIAAASNNTTTANDSMWINIMQTEVTRLSSKVTAHEHNVREMFEHRARDAKTAMDDMVSEMNKRMDDLAARIVVLEDEKAELRRINQRLTEKVRDKDMEKAAVNDIGIKNKDRHLPEVDGSQPMITNDVSYHLVEDACRRSARKLYLLVEEVKLYKPDCKFEDYRHISSTPRINTWDSDYDEEEHERQKQTIKTLLEPLIVKIGDTGLVDIRRLYKACIRCDMSSSASVMRKDCFYDRDVANMM
What are the official names of this protein?
Uncharacterized protein ORF3.
Protein: RL13_PSEPK
Sequence: MKTFTAKPETVKREWFVVDAAGQTLGRLATEIATRLRGKHKPEYTPHVDTGDYIVVINAEQVRVTGAKSSDKMYYSHSGFPGGIKEINFEKLIAKAPERVIETAVKGMLPKNPLGRDMYRKLKVYAGAAHPHTAQQPQELKI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: Y687_HALH5
Sequence: MSKQQAPVNKNDVVEVTIEDLTHDGAGVAKVDGYALFIPKALPGERLKAKVVKVKKGYGFGRVLNMIEASPDRVEAPCPVFNQCGGCQLQHMSYDAQLRYKQKQVQDVLERIGKITAVTVRPTIGMNEPWRYRNKAQVPVGEREGGLIAGFYQERSHRIIDMDECMIQHEENDKVIRQVKELARELGIRGYDEEKHRGTLRHVVARYGKNTGEIMVVLITRGEELPHKKTLIERIHKAIPHVKSIVQNVNPKRTNVIFGDKTKVLWGEEYIYDTIGDIKFAISARSFYQVNPEQTKVLYDQALEFANLTGSETVIDAYCGIGTISLFLAQQAKHVYGVEIVPEAISDAKRNARLNGFANVQFAVGDAEKVMPWWYAQGVRADVIVVDPPRKGCDEALLKTILNMKPDRVVYVSCNPATLARDLRVLEDGGYETKDVQPVDMFPWTTHIESVAVLELKN
What are the official names of this protein?
Uncharacterized RNA methyltransferase BH0687.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: BETI_ECO5E
Sequence: MPKLGMQSIRRRQLIDATLEAINEVGMHDATIAQIARRAGVSTGIISHYFRDKNGLLEATMRDITSQLRDAVLNRLHALPQGSAEQRLQAIVGGNFDETQVSSAAMKAWLAFWASSMHQPMLYRLQQVSSRRLLSNLVSEFRRELPRHQAQEAGYGLAALIDGLWLRAALSGKPLDKPLAHSLTRHFITQHLPTD
What is the function of this protein?
Repressor involved in the biosynthesis of the osmoprotectant glycine betaine.  It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator BetI.
Protein: SLD5_ASHGO
Sequence: MDINIDDILADLDRDTTAVGSTPAPAGDDTTRLDDSAATVAADYSTLVTHWCNERVAPELLPYPHTLMARVLARLAAQIEHLETLSTGVLEQTLDRSAKLPLLCMEAELERLKFVVRSLLRCRLGKIDRFGLYLRQLDARSPGALQTLLSAQERVYYERHSAILLKLFNNAILRHMPAEMQAVDDTEGSVSMIDEPEWARFVFLYVREPAPDAPDPLLAVDDHGQPCYSVNIPELGEVVDLAVGGIYIMRYNVIKDLLMDGKVVLI
What is the function of this protein?
The GINS complex plays an essential role in the initiation of DNA replication.  Has a role in chromosome segregation (By similarity).
What are the official names of this protein?
DNA replication complex GINS protein SLD5.
What is the protein family that this protein belongs to?
Belongs to the GINS4/SLD5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRG_STAS1
Sequence: MTKFIFVTGGVVSSLGKGITAASLGRLLKDRGLKVTIQKFDPYLNVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTAGKVYSHVLKKERRGDYLGGTVQVIPHITNEIKERLLLAGESTNADVVITEIGGTTGDIESLPFIEAIRQIRSDLGRENVMYVHCTLLPYIKAAGEMKTKPTQHSVKELRGLGIQPDLIVVRTEYELTQDLKDKIALFCDIDKASVIECRDADSLYEIPLQLSKQDMDDIVIKRLELNPKYETQLDEWQYLLDTVNSLDGKITIGLVGKYVSLQDAYLSVVESLKHAGYPFKKDIEVKWIDSSEVTDENVAEILAEVDGILVPGGFGFRASEGKISAIKYARENNVPYFGICLGMQLATVEFARNVIGLDDAHSAELDPNTPHPIIDLLPEQKDIEDLGGTLRLGLYPCHIKEGTLADSIYNETEIEERHRHRYEFNNEYREQLEANGMVFSGTSPDGRLVEMVEIPSNDFFVACQFHPEFLSRPNRPQPIFKAFIEASLNHQQSK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: PTHB1_CAEEL
Sequence: MSLFRLVEWVSQTIPNTSTILNASFFQDREQLVIGGENGQITISDPGFRDTNAHVLCTTETKYAILQMASDNFLPSMNNILAVLSPTKLTYYKVHFASPDETLASLDEIFSHSFSTSAWNMCVIPIEESTPQILVQSIDCKLSLFQGDQCVFSMVPLRALQPGPIGYCQTTQTLFVANNGFLAAIKFSLMSSGSQKKINYDWSFNLGDTAIQMKVTEGSKPTTIVLCRRHVSAFNATGSVVWQIRLEAVGMAMCLYRSLLINNTQFNRLIVSTSDDTLLIFQDNKLVWNCNAQMSPVALLVCSYNKSYENTITMMAPDGKVVVGYLGTEPNLYRLPEDKVIVNYAERMEEYKRMEQKIKESDAAGGAIKRKEGIQMKLSIGEIGKRTIEPNAASNAPYCNLIVEFSEVQNVSKLHINILSECASPSKQVILNVGTSKSTASIEIPFYVGSKKSPTSNKVTIAAHCAFTQLTVTKSIDLPFKVLFEESQIDRNAKYKVTIDTAGSVMPLNKLFSEFESENPQAIGFSLHGSDKTVSVFAANKSNRYRIQSEHISLLQITSRELVKRIAESAPGIEIGGVIPFEYMRETLDEIQELQTKKKEDSKKIDCRTKEVRAIEALSLNSCKTGNMGNLPSLDALFDKSYRELLDAMDSYNSLTAKIENQKASLNSLFQLAADLSKLSKVDTILNGSFWANTQQSLRDRLRWAVKTDRGNEMTMIEKLCEHSPKELPKIREEEEEEEQQVTA
What is the function of this protein?
Component of the BBSome complex (By similarity).  The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia (By similarity).  The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function (By similarity).  Required for proper BBSome complex assembly and its ciliary localization (PubMed:22922713).  Required for cilia biogenesis and both the assembly and movement of intraflagellar transport proteins along the ciliary axoneme (PubMed:22022287, PubMed:22922713).  In ciliated sensory neurons, required for the sensation of nitric oxide and avoidance of NO-producing organisms like P. aeruginosa (PubMed:30014846).
What are the official names of this protein?
Protein pthb1 homolog, Bardet-Biedl syndrome 9 protein homolog.
Protein: KATG_YERPS
Sequence: MLKKILPVLITLAIVHNTPTAWAAEAPKTDSFYLPKSLDLSPLRLHNIESNPYGKDFNYAQQFKTLDLEAVKKDIKTVLTTSQDWWPADYGNYGPFFIRMAWHGAGTYRIYDGRGGADGGQQRFEPLNSWPDNANLDKARRLLWPIKKKYGAKISWGDLMVLTGNVALESMGFKTLGFAGGREDDWQSDLVYWGAGNKMLSDNRDKNGKLPKPLAATQMGLIYVNPEGPNGKPDPVAAAKDIREAFARMAMNDEETVALIAGGHTFGKAHGAASPEKCLGAAPGEAGLEQQGLGWANKCGSGNGKDTITSGLEGAWTTDPTHFTMQYLSNLYKHEWVLTKSPAGAWQWKPKNAANVVPDATDPTKFHPLMMFTTDIALKVDPEYKKITTRFLENPEEFKMAFARAWFKLTHRDMGPAARYLGDEVPKETFIWQDPLPAANYKMIDSADISELKDKILKTGLSDTKLIKTAWASASTFRGTDFRGGDNGARIRLAPQKDWPVNDPAELHSVLAALMEVQNNFNKDRSDGKKVSLSDLIVLGGNAAIEDAAKKAGYSISIPFTPGRTDASQEETDVSSFAVLEPTADGFRNYYDAKRNTLSPIASLIDRANKLELTVPEMTVLIGGLRVLDVNSGGSKAGVLTNTPGQLNNNFFVNLLDMSTKWTKSPKAEGYFDGYDRKTGKLKWTASSVDLVFGSNPELRAVAEVYASDDAKEKFVHDFTKVWEKVMNLDRFDIKNN
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: FIXB_ECOSE
Sequence: MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGVQAIQLGANHVWKLNGKPDDRMIEDYAGVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYRLKAAVSNDASTVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDASRTGETHTVEWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLCKAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANASQTIFAINKDKNAPIFQYADYGIVGDAVKILPALTAALAR
What is the function of this protein?
Required for anaerobic carnitine reduction.  May bring reductant to CaiA.
What are the official names of this protein?
Protein FixB.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
Protein: TENS4_HUMAN
Sequence: MSQVMSSPLLAGGHAVSLAPCDEPRRTLHPAPSPSLPPQCSYYTTEGWGAQALMAPVPCMGPPGRLQQAPQVEAKATCFLPSPGEKALGTPEDLDSYIDFSLESLNQMILELDPTFQLLPPGTGGSQAELAQSTMSMRKKEESEALDIKYIEVTSARSRCHDGPQHCSSPSVTPPFGSLRSGGLLLSRDVPRETRSSSESLIFSGNQGRGHQRPLPPSEGLSPRPPNSPSISIPCMGSKASSPHGLGSPLVASPRLEKRLGGLAPQRGSRISVLSASPVSDVSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSSSLHSLGSVSLCTRPSDFQAPRNPTLTMGQPRTPHSPPLAKEHASSCPPSITNSMVDIPIVLINGCPEPGSSPPQRTPGHQNSVQPGAASPSNPCPATRSNSQTLSDAPFTTCPEGPARDMQPTMKFVMDTSKYWFKPNITREQAIELLRKEEPGAFVIRDSSSYRGSFGLALKVQEVPASAQSRPGEDSNDLIRHFLIESSAKGVHLKGADEEPYFGSLSAFVCQHSIMALALPCKLTIPQRELGGADGASDSTDSPASCQKKSAGCHTLYLSSVSVETLTGALAVQKAISTTFERDILPTPTVVHFKVTEQGITLTDVQRKVFFRRHYPLTTLRFCGMDPEQRKWQKYCKPSWIFGFVAKSQTEPQENVCHLFAEYDMVQPASQVIGLVTALLQDAERM
What is the function of this protein?
Promotes EGF-induced cell migration by displacing tensin TNS3 from the cytoplasmic tail of integrin ITGB1 which results in dissociation of TNS3 from focal adhesions, disassembly of actin stress fibers and initiation of cell migration (PubMed:17643115).  Suppresses ligand-induced degradation of EGFR by reducing EGFR ubiquitination in the presence of EGF (PubMed:23774213).  Increases MET protein stability by inhibiting MET endocytosis and subsequent lysosomal degradation which leads to increased cell survival, proliferation and migration (PubMed:24814316).
What are the official names of this protein?
Tensin-4, C-terminal tensin-like protein.
What is the protein family that this protein belongs to?
Belongs to the PTEN phosphatase protein family.
What are the subcellular locations of this protein?
Cell junction, focal adhesion. Cytoplasm, cytoskeleton.
Protein: RL361_SACEN
Sequence: MKVRASLKSLKDKDGSQVVRRRGKLYVVNKRNPRWKGRQG
What are the official names of this protein?
50S ribosomal protein L36 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: SIA7F_MOUSE
Sequence: MACSRPPSQCDPTTLPPGPPAGRWPLPFSRRRREMSSNKEQRSAVFVILFALITILILYSSNSANEVFHYGSLRGRTRRPVNLKKWSFSSAYFPILGNKTLPSRCNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVVAHSSVFRVLRKPQEFVNRTPETVFIFWGPPNKMQKPQGSLLRVIQRAGLMFPNMEAYAVSPARMQQFDDLFRGETGKDREKSHSWLSTGWFTMVIAVELCDHVHVYGMVPPDYCSQRPRLQRMPYHYYEPKGPDECVTYIQNEHSRKGNHHRFITEKRVFSSWAQLYGITFSHPSWT
What is the function of this protein?
Transfers the sialyl group (N-acetyl-alpha-neuraminyl or NeuAc) from CMP-NeuAc onto glycolipids, forming an alpha-2,6-linkage.  Produces branched type disialyl structures by transfer of a sialyl group onto the GalNAc or GlcNAc residue inside backbone core chains having a terminal sialic acid with an alpha-2,3-linkage on Gal.  ST6GalNAcVI prefers glycolipids to glycoproteins, predominantly catalyzing the biosynthesis of ganglioside GD1alpha from GM1b.  Also has activity toward GD1a and GT1b, and can generate DSGG (disialylgalactosylgloboside) from MSGG (monosialylgalactosylgloboside) (PubMed:10702226).  Besides GMb1, MSGG and other glycolipids, it shows activity towards sialyl Lc4Cer generating disialyl Lc4Cer, which can lead to the synthesis of disialyl Lewis a (Le(a)), suggested to be a cancer-associated antigen (By similarity).
What are the official names of this protein?
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6, GalNAc alpha-2,6-sialyltransferase VI, ST6GalNAc VI, ST6GalNAcVI, Sialyltransferase 7F, SIAT7-F.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: GTR3_DROME
Sequence: MRKGGIQDAEPVEPPQSSRKSGTWFAKRPSEMPERHVERAPVRQKINNVGLYKATLYSNIGSFFFGIAVGWSGTAERSVMEQHSYSFQPTELQWSGVCILLTLGAALWCLPMGLMVRLLGCRRTILIQLLPNFLGWFLTVFARSVPMLYAGRFFLGMCGGAHCVVVPIYNAEISTTKKRGAMGVVFEGACICGVIYSFAMSLFLELRIINFVNLGLLALGPLQILMPESPAYYVDHGNIPRAEDSLRFLRGQKYDTRREIDFLTRDPTESEREVRQGPLLGFKYKKVRRSLARSLAIALLQKLCGALIFIFYGLNMLDCLRIRREFGLILCLGLILGFLACFFLVDRLGRRPLLIFSSAGIVFVSIYLGLHFKVWMTMGLTVMSWIALFCIAIFVGCYTAGVGSLTWVLNAELLVRPMRPLGCSIVCAFNWLTAFFVICWFGSHGVKCQPYLFLLFAIIASLILLFSLIYIPETKKLSSAKIQQRLGGLINRPAVITFTSSSDSSNA
What is the function of this protein?
Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane.
What are the official names of this protein?
Glucose transporter type 3, Glucose transporter-like protein.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Perikaryon. Cell projection. Note=Localized to densely spaced patches along neuronal processes.
Protein: RLMM_PSYIN
Sequence: MLGILLYCRPGFENDCANELQDKATALEVFGFVKTKRNSGYVFYQCYDPQQVEYLLEKLDYKQLIFARQLIAVKAFINDLPLDDRISPILEITRNLPLGGDLYVETPEGDDTKPLLTFCRKFTVPLRQALRKHNSLTAKENRNKIFYHLCFLDNKSAYIGFSVPHNRSEFYMGIPRLRSPSEAPSRSTLKLDEAIQVFLTAEEQQERLHSGMRAVDLGACPGGWTYQLVRRGLFVTAIDNGAMAQSLMDTGQVTHYTVDGFKYEPERKNIDWLVCDMIEKPKRVAKLMGQWLIDGWCKEAIFNFKLPMKKRYQEASEDIKILTDMFEKEDLQYELQAKQLYHDREEITLHVRLIGNHWGKQLGNG
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQP2_CAEEL
Sequence: MFLRVIDFFQLHLRWYSVGLIFFSFIPIYYSIIVCQPQQFKIDGFELINPVFNKHHSTRSCTSATKSLQNGLIALFIFYALKIYKKVYLIVLYIILIIHFGFEIRNAKSETSRKYIAISTREMFMYYVELLLLYFQNLLLLPYICGGYFLIRHVHRIPSKEEVDRQTLKFKEEARRIKRLMIEEDWHVKEANEDVKNKIEQEGLKRKDMEFEEQLYHLRIEKVKRREQVLKQKLEEKKAKRRQNAERRKKRREIAMEQREQ
What are the official names of this protein?
Uncharacterized protein F07F6.2.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.