PharMolix/UniProtQA huggingface dataset:
Protein: DKK3_MOUSE
Sequence: MQRLGGILLCTLLAAAVPTAPAPSPTVTWTPAEPGPALNYPQEEATLNEMFREVEELMEDTQHKLRSAVEEMEAEEAAAKTSSEVNLASLPPNYHNETSTETRVGNNTVHVHQEVHKITNNQSGQVVFSETVITSVGDEEGKRSHECIIDEDCGPTRYCQFSSFKYTCQPCRDQQMLCTRDSECCGDQLCAWGHCTQKATKGGNGTICDNQRDCQPGLCCAFQRGLLFPVCTPLPVEGELCHDPTSQLLDLITWELEPEGALDRCPCASGLLCQPHSHSLVYMCKPAFVGSHDHSEESQLPREAPDEYEDVGFIGEVRQELEDLERSLAQEMAFEGPAPVESLGGEEEI
What is the function of this protein?
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6.  DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation.  In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
What are the official names of this protein?
Dickkopf-related protein 3, Dickkopf-3, Dkk-3, mDkk-3.
What is the protein family that this protein belongs to?
Belongs to the dickkopf family.
What are the subcellular locations of this protein?
Secreted.
Protein: ASK10_ARATH
Sequence: MSTKKIILKSSDGHSFEVEEEAACQCQTIAHMSEDDCTDNGIPLPEVTGKILEMVIEYCNKHHVDAANPCSDEDLKKWDKEFMEKYQSTIFDLIMAANYLNIKSLLDLACQTVADMIKDNTVEHTRKFFNIENDYTHEEEEAVRRENQWGFE
What is the function of this protein?
Involved in ubiquitination and subsequent proteasomal degradation of target proteins.  Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex.  The functional specificity of this complex depends on the type of F-box protein.  In the SCF complex, it serves as an adapter that links the F-box protein to CUL1 (By similarity).
What are the official names of this protein?
SKP1-like protein 10, AtSK10.
What is the protein family that this protein belongs to?
Belongs to the SKP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: URE3_ACTP2
Sequence: MHLTSREQEKLMLFLAGELAAKRKARGVKLNYPEAIAYIASHLQEAARDGMSVAEVMQYGATLLTVDDVMEGIAEMVHEVQIEATFPDGTKLVTVHNPIR
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_BORBR
Sequence: MSGLAYLDLPAARLARGEVALPGSKSISNRVLLLAALAEGSTEITGLLDSDDTRVMLAALRQLGVSVGEVADGCVTIEGVARFPTEQAELFLGNAGTAFRPLTAALALMGGDYRLSGVPRMHERPIGDLVDALRQFGAGIEYLGQAGYPPLRIGGGSIRVDGPVRVEGSVSSQFLTALLMAAPVLARRSGQDITIEVVGELISKPYIEITLNLMARFGVSVRRDGWRAFTIARDAAYRGPGRMAIEGDASTASYFLALGAIGGGPVRVTGVGEDSIQGDVAFAATLAAMGADVRYGPGWIETRGVRVAEGGRLKAFDADFNLIPDAAMTAATLALYADGPCRLRNIGSWRVKETDRIHAMHTELEKLGAGVQSGADWLEVAPPAPGGWRDAHIGTWDDHRMAMCFSLAAFGPAAVRILDPGCVSKTFPDYFDVYAGLLAARD
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP2_CLOD6
Sequence: MAKNEKQFVEEITKMEDDFPQWYTDVITKTDLVDYAPVKGFMVVKPYGYALWEKMQEFMDKKFKETGHKNCYFPLLIPESLLNKEAEHVEGFAPEVAWVTHGGNKKLEERLCVRPTSETIICTMYAKWLKSYRELPYLYNQWCSVVRWEKSTRPFLRTSEFLWQEGHTLHETAEEAQEETIQQLEVYKALCEELLAMPVVAGQKSESEKFAGGERTYTIEAMMHDGKALQSGTSHFLGQHFTKAFDITFADREGNLANPYHTSWGASTRLIGGLIMTHSDNRGLVLPPRVAPIQVVIVPIAAKKGNVMETVDKIYADLKAKGVAVEVDDRDNYTTGWKFNEWEMKGVPVRVEIGPKDIENNQAMVFRRDTLEKDSMPLEGLADAICDLFDVIHNDMFEKARKHREDNTSIVENMDEFRKALEEKPGFIKTMWCGDAECEAKIKEETGATIRCLPFEQENLGHKCVYCGKEADSMVVMAKAY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase 2, Prolyl-tRNA synthetase 2, ProRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR4_SALTY
Sequence: MMEILRGSPALSAFRINKLLARFQAANLQVHNIYAEYVHFADLNAPLNDSEQAQLTRLLQYGPALSSHTPAGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVDRLERGVAYYIEASTLTAEQWRQVAAELHDRMMETVFSSLTDAEKLFIHHQPAPVSSVDLLGEGRQALIDANLRLGLALAEDEIDYLQEAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGKPQPKSLFKMIKNTFETTPDYVLSAYKDNAAVMEGSAVGRYFADHNTGRYDFHQEPAHILMKVETHNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIVTALDIMTEGPLGGAAFNNEFGRPALTGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNIRADHVQKGEIVVGAKLIVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERRCQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPLEIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGDATEEQHLSLHDNHFDNQPIDLPLDVLLGKTPKMTRDVQTLKAKGDALNRADITIADAVKRVLHLPTVAEKTFLVTIGDRTVTGMVARDQMVGPWQVPVADCAVTTASLDSYYGEAMSIGERAPVALLDFAASARLAVGEALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYDAVKAVGEELCPQLGLTIPVGKDSMSMKTRWQEGNEQREMTSPLSLVISAFARVEDVRHTLTPQLSTEDNALLLIDLGKGHNALGATALAQVYRQLGDKPADVRDVAQLKGFYDAMQALVAARKLLAWHDRSDGGLLVTLAEMAFAGHCGVQVDIAALGDDHLAALFNEELGGVIQVRAEDRDAVEALLAQYGLADCVHYLGQALAGDRFVITANDQTVFSESRTTLRVWWAETTWQMQRLRDNPQCADQEHEAKANDTDPGLNVKLSFDINEDIAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLGGRIGLGNFHALVACGGFSYGDVLGAGEGWAKSILFNHRVRDEFETFFHRPQTLALGVCNGCQMMSNLRELIPGSELWPRFVRNHSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGRVEVRDDAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTENGRVTIMMPHPERVFRTVANSWHPENWGEDSPWMRIFRNARKQLG
What is the function of this protein?
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase, FGAM synthase, FGAMS, Formylglycinamide ribonucleotide amidotransferase, FGAR amidotransferase, FGAR-AT.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HXK7_ORYSJ
Sequence: MVAAAVAAAEQVVAALREECATPAARLDGVAAAMAGEMAAGLAEEGGSKIKMIVSYVDNLPNGTEEGLFYALDLGGTNFRVLRVQLAGKEKRVVKRESREVSIPPHLMSGNSSELFGFIASALAKFVADEGHNAVFNDRQRELGFTFSFPVRQTSIASGTLIKWTKAFSIDDAVGEDVVAELQMAMEKQGLDMRVSALINDTVGTLAAGSYYDEDIVVGVILGTGSNAAYLEKANAIPKLEGELPKSGNMVINTEWGNFSSSCLPITEYDEALDKESLNPGEQIFEKLISGMYLGEIVRRVLLKISLQSSIFGNLDQTKLKTRFILRTPDISVMHHDGTPDLRIVAEKLADNLKITDTSLETRKMVVEICDIVTRRSARLAAAGIVGILRKIGRGVPGDKRKSVIAIDGGLYEHYTEFRQCLETTLTELLGEEASKSVAVKLANDGSGLGAALIAAAHSQYLN
What is the function of this protein?
Fructose and glucose phosphorylating enzyme (PubMed:16552590).  Functions in sugar signaling via a glycolysis-dependent manner under aerobic conditions, but its signaling role is suppressed when oxygen is deficient (PubMed:25951042).
What are the official names of this protein?
Hexokinase-7, Hexokinase-6.
What is the protein family that this protein belongs to?
Belongs to the hexokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_BACLD
Sequence: MLKDIFSKKKKKYASVPAESAKQDVPEGIMTKCPDCKKIMLTKELDKNLRVCMNCGYHLQMNAKQRIKSLLDDGSFEEFNQDMMSENPLEFPGYLEKLQKDREKTSLNEAVVTGKGTIDGSPAVVAVMDSSFRMGSMGSVVGEKITLAIEKAREEKVPFIIFTASGGARMQEGLLSLMQMAKTSSALKLFSEEQGLIISVMTHPTTGGVSASFASLGDYNLAEPGALIGFAGRRIIEQTIREELPEDFQTAEFLLKHGQLDSVVHRADMKKTLGSILKMHQTGGDLEWLEN
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF2_PIPCE
Sequence: MKGHQFQSWIFELREILREVKNSHYFLDSWTQFDSVGSFTHIFFHQERFMKLFDPRIWSILLSRDSQGSTSNRYFTVKGVVLLVVAVLIYRINNRNIVERKNLYLRGLLPIPILPIPMNSIGPRNDTLEESFWSSNINRLIVSLLYLPKGKKISESCFMDSKESAWVLPITKKKCIIPESNWGSRWWRNRIGKKRDSSCKISNETETIAGIEISFKEKDIQYLKFLFVSYTDDPIRKDHDWELFDRLSPRKKRNIINLNSGQLFEILVKHLICYLMSAFREKRPIEMGGFFKQQGGAGATIQSNDIEHVSHLFSRKKWGIFLQNCAQFHMWQFYQDLFVSWGKNQHESDFLRNVSRDNWIWLDNVWLVNKDRFFSKVLNVSSNIQYDSTRSIFVQVTDSSQLKGSSDQSGDHFDSIRNENSEYHTLINQTEIQQLKERSILWDPSFLQTERTEIESDRFPKCLSGYSSISRLFTEREKQMNNHLLPEEIEEFLGNPTRSIRSFFSDRWSELRLGSNPTERSTRDQKLLKKQQDVSFVPSRRSENKEMVAIFKIITYLQNTVSIHPISSDPGCDMVPKDEPDIDSSHKISFLNKNPFLDLFHLFHDRNKGGYTLHHDFESEERFQEMADLFTLSITEAGLVYHKGFTFSIDSYGLDQKKFLNEVFNSRDESKKKSLWFLPPIFDEENESFYGRIRKKSARISCGNDLEDPNPKIVVFSSNNIMGAVNQYRLIRNLIQIQYRTYEYIRNVSNRFFLMNRPDRNFEYGIQGDPIGNDTLNHLTIIKHTINQHLSNLKKSQKKWFDPLISRTERCMNRDPDAYRYKWSNGSKNFQEHLEHFVSEQKHRFQVVFGRLRINQYSIDWSEVIDKQDLSKSLRFFLSKSLLFLSKSLRFFLSKSLPFFFVSIGNIPIHRFEIHIYELKGPNDQLCNPLLESIGVQIVHLNKLKPFLLDDHDISQRSKFLINGGTISPFLFNKIPKWMIDSFHTRKNRRKSFDNTDSYFSMISHDRDNWLNPVKPFHRSSSISSFYKANRLRFLNNPHHLWFYCNKRFPFDVEKARINNYDLTYGQFLNVLFIRNKIFSLCVRKKKHVFGGRDAISPIESQVSDIFIPNDFPQSGDETYNLYKSFHFPIRSDSFVRRAIYSIADISGTPLTEEQIVHFQRTYCQPLSDMNLSDSEGKNLHQYLRFNSNMGLIHTLCSEKDFPSGKRKKRTLCLKKCVEKWQMYRTFQRDNDFSNLSKWNLFQTYMPWFLTSTGCKYLNFTLLDTFSDPLPILSNSPKFVSIFHDIMHGSDISWPIPQQKGRAILPQRNWISEMSSKCLQNLLLYEEIIHRNNESPALLIWTHLRSPNARELLYSILFLLLVAGYLVRTHLLFVSRASSELQTELEKIKSLMIPSYMMELRKLLDRYPTPELNSFWLKNLFLVALEQLGDSLEEIRGSASGGNILLGGGPAYGVKSIRSKKKYLNINLIDIIDFISIIPNPINRITFSRNTRHLSHTSKEIYSLIRKRKKNVNGGWIDEKIESWVANSDSIDDEEREFLVQFSTLTTEKRIDQILLSLTHSDHLSKNDSGYQMIEQPGSIYLRYLVDIHKKYLMNYEFNRSCLAERRIFLAHYQTITYSQTSCGTNSSHFPSHGKPFSLRLALSPSRGILVIGSIGTGRSYLVKYLATNSYVPFITVFPNKFLDDKPKGSLFDNIDIDDSDDIDIDDSDDIDIDDSDNIDDLDTELLTMTNVLTMYMTPKIDRFDITLQFELAKAMSPCIIWIPNIHDLYVNESNYLSLGLLVNYLSRDCERCSTRNILLIASTHIPQKVDPALIAPNKLNTCIKIRRLLIPQQRKHFFILSYTRGFHLEKKMFHTNVFGSITMGSNARDLVALTNEALSISITQKKSIIDTNTIRSAIHRQTWDLRSQVRWVQDHGILFYQIGRAVAQNVLLSDCPIDPISIYMKKKSCKEGDSYLYKWYFELGTSMKKLTILLYLLSCSAGSVAQDLWSPPGPDERNCITSYGFVENDSDLVHGLLEVEGALVGSSRTEKDCSQFDNDRVILLLRSEPKNPFDMIQNGSCSIVDQRFLYEKYESELEEGEGEGALDPQQIEEDLFNHIVWAPRIWRPCGNLFDCIERPNELGFPYWWTRSFRGKRILYHKEDALQENDSEFLQSGTVRYQRLDRSSKEQGFFRISQFIWDPADPFFFLFKDQPFVFSRREFFADEEMSKGLITSQTNPTTSIYKRWFIKNTQQNHFELLIHRQRWLRTNSLLSNGSFRSNTLSESYQYLSNLFLSNRTLLDQMTKALLRKRWLFPDEMKHWIHVTGERFPIP
What is the function of this protein?
Probable ATPase of unknown function.  Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
What are the official names of this protein?
Protein Ycf2.
What is the protein family that this protein belongs to?
Belongs to the Ycf2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: IF3M_SCHPO
Sequence: MNSYLQFPHRKLFIQFSYSLTSVFRKCQSRTFMNSQFASAKLSNSIKKYFDGRIDESIKYQEIFIRGLENKGKLSKTSLVEALARVRAKPETVLYKVADPNENNKYPICSIISYTELSKLRENQSSRLREAEKSKHKNKTRTRYVLFSWRTDVNDIERKLKSVKDFLQDGNIVEIHVQNKKRSQPVSQEVRDSILSKIQLEIEGLGKDMKPPIVNSHSATFLLQPLVSKSSEL
What is the function of this protein?
May be involved in mitochondrial translation initiation.
What are the official names of this protein?
Probable translation initiation factor, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
Protein: GLUC_OCTDE
Sequence: MKSIYFVAGLFVMLVQGSWQHPLQDTEEKPRSFSTSQTDLLDDPDQMNEDKRHSQGTFTSDYSKFLDTRRAQDFLDWLKNTKRNRNEIAKRHDEFERHAEGTFTSDVSSYLEGQAAKEFIAWLVKGRGRRDFPEEVTIVEELRRRHADGSFSDEMNTVLDHLATKDFINWLIQTKITDRK
What is the function of this protein?
May modulate gastric acid secretion and the gastro-pyloro-duodenal activity.  May play an important role in intestinal mucosal growth in the early period of life.
What are the official names of this protein?
Pro-glucagon.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted. SUBCELLULAR LOCATION: [Glucagon-like peptide 1]: Secreted.
Protein: HSLU_ECOK1
Sequence: MSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQTEQQQEPSAARQAFRKKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGESSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQTITIDADYVSKHLDALVADEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Heat shock protein HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP74_MOUSE
Sequence: MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACVSFGPKNRSIGAAAKSQVISNAKNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLSKLKETAESVLKKPVVDCVVSVPSFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNKGKLKVLATAFDTTLGGRKFDEVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDIDVSGTMNRGKFLEMCDDLLARVEPPLRSVLEQSKLKKEDIYAVEIVGGATRIPAVKEKISKFFGKELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGLSDCEVFPKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKVKVRVNVHGIFSVSSAALVEVHKSEESEEPMETDQNAKEEEKMQVDQEEPHTEEQQQQPQTPAENKAESEEMETSQAGSKDKKTDQPPQAKKAKVKTSTVDLPIEHTLWQLDREMLALYTENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNTFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKSLGQPIKTRFQESEERPKLFEELGKQIQQYMKVISSFKNKEDQYEHLDAADVTKVEKSTNEAMEWMNSKLNLQNKQSLTVDPVVKTKEIEAKIKELTSICSPIISKPKPKVEPPKEEPKHAEQNGPVDGQGDNPGSQAAEHGADTAVPSDGDKKLPEMDID
What are the official names of this protein?
Heat shock 70 kDa protein 4, Heat shock 70-related protein APG-2.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_WALAE
Sequence: MSNQHILLMSNLLPVGSNISTWWNFGSMLLTCLILQIMTGFFLAIHYTANINLAFSSVIHITRDVPYGWIMQNLHAIGASLFFICIYIHIARGLYYGLYLNKEVWLSGTTLLIILMATAFFGYVLPWGQMSFWAATVITNLLTAIPYLGTTLTTWLWGGFSINDPTLTRFFALHFILPFTIISLSSIHIILLHNEGSNNPLGTNSDIDKIPFHPYHTYKDMLMIIIMTAILFLILSFSPNLLNDPENFSKANPLVTPQHIKPEWYFLFAYGILRSIPNKLGGTLALVMSVMILTTAPFTHTSHTRSMMFRPLSQIVFWTLIATFITITWTATKPVEPPFISISQTASIFYFSFFIMNPLLGWTENKIMMMND
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: BIOC_PROA2
Sequence: MQQLNKTLIRQRFGRQLHGYNRHAFIQKKMAGHLADMVSASLASSEVGRLFEIGVGSAALTDALLHRLRIDRYYANDLVPQCRQMVETVTALHGVDSAEFLDGDIEALREIPGDLDVIVSGATVQWLEDLPGFFHRMAGALKPGGVLAFSTFGHDNMQEIRALESVGLHYHTLAEMQAMAGELYEVTGMEEERHQLDFTGPEAVLRHISRTGVNGLDGRAWTKSRHRAFIDRYRRAFSSGDGVRLTYHTMYCCFRKCPASAGVEATCC
What is the function of this protein?
Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM).  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
What are the official names of this protein?
Malonyl-[acyl-carrier protein] O-methyltransferase, Malonyl-ACP O-methyltransferase, Biotin synthesis protein BioC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: SECA_GLUOX
Sequence: MFARLARALFGSANDRTLKAYQRRVPEINALEPAVQALSDEQLRHKTTEFKERLEKGETLDGLLPEAFAVCREASRRVLGKRHFDVQLIGGMVLHAGRIAEMRTGEGKTLVATLAVYLNALSGKGVHVVTVNDYLARRDAEEMSILYSFLGLTTGVIVPNLSDGERREAYAADITYGTNNEFGFDYLRDNMKYSLADMVQRPFNHAIVDEVDSILIDEARTPLIISGPADDSSDLYRSVDDVVVKLVQEPDVYDKDEKLRSVTLTEHGSHRVEELLAEAGVLQDGGLYDIHNVAVVHHVQQSLRAHTLFTRDVDYIVRDGKVVIIDEFTGRMMDGRRYSDGLHQALEAKEHVEIQQENQTLASITFQNYFRLYPKLSGMTGTAMTEADEFAEIYHLDVVEIPTNLPVRRIDTDDEVYLTAAEKFSAVADLIKEIHETGQPILVGTTSIEKSEYLSHILTQRGIPHNVLNARQHEKEAIIVAQAGAPGAITIATNMAGRGTDIKLGGNIEMLVKASTEGVEDEAQRESVEQNIRAIVEEHHEEVHKAGGLYVIGTERHESRRVDNQLRGRSGRQGDPGNSRFFLSLEDDLIRIFASDRMGAMMQKMGLKEGEAIVHPWLNKALEKAQKRVEARNFDMRKNTLKYDDVMNDQRKEVYAQRREYMATDDLSGVIAELREHTIEDLVHAHIPEKSFAEAWDTEGLTKEVSRILNLDLPIADWAKEDGMDSEGVIERIEAEAAKAQAARTANMGPELMRLIEKQVVLTTFDAVWKEYLHGLDQLRQGIGLRAYGQRDPLNEYKQEAFQMFTAMLDDMRIRVTETMCRIQAVSEPPPFPVINTETSGPSEEPAGLFSQGTTGGDIPAPQPMAGFPSAAPMPPRPQPVPTGAEPDAATLQRWYAETPRNALCPCGSGLKFKHCHGRLA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: RNPA_RICCN
Sequence: MSITSLKNQKEFELINKLGKKLHERYFILVIATKLPKIFLESKYNTFLGIKVSRKLNKKAVVRNKIKRRIRHLIRIIVSDSSFKAIKFAMIIIPRKGFEEINFSHLNYELSKVILRNI
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: VE2_HPV6A
Sequence: MEAIAKRLDACQEQLLELYEENSTDLNKHVLHWKCMRHESVLLYKAKQMGLSHIGMQVVPPLKVSEAKGHNAIEMQMHLESLLKTEYSMEPWTLQETSYEMWQTPPKRCFKKRGKTVEVKFDGCANNTMDYVVWTDVYVQDTDSWVKVHSMVDAKGIYYTCGQFKTYYVNFVKEAEKYGSTKQWEVCYGSTVICSPASVSSTTQEVSIPESTTYTPAQTSTPVSSSTQEDAVQTPPRKRARGVQQSPCNALCVAHIGPVDSGNHNLITNNHDQHQRRNNSNSSATPIVQFQGESNCLKCFRYRLNDKHRHLFDLISSTWHWASPKAPHKHAIVTVTYHSEEQRQQFLNVVKIPPTIRHKLGFMSLHLL
What is the function of this protein?
Plays a role in the initiation of viral DNA replication.  A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity.  Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA.  E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome.  Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box.  Repression occurs by sterically hindering the assembly of the transcription initiation complex.
What are the official names of this protein?
Regulatory protein E2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E2 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: UVRC_CHLCV
Sequence: MRVKDFTPKLVPTSPGVYLMKDDSGEVLYIGKAKNLRNRITTYFQKQGDSRERIPFLMKKTTTIETILVSNETEALLLENNLIKKHHPKYNVLLKDDKTFFCLAISLTHPWPKIDAIRTKAITSSKRQIIFGPYVSAEACRTLLEVISQWFPLRTCSNREFASRRRPCILYEMKRCLAPCVHLCTHEEYEETLEKAVLFLKGKVSEIIQDLEKSIEKASQEQKFEQAGIYYRTLKLIQQAMEKQHVEKFHFQNIDAIGLYRKYQETVITVLTVRSGKLLGARHFPFSENAQEDTDLLSSFILQYYANQPQTPKEILTPIPLNIPELPYLLNKDTPPQLRSPKTGYGKELLTLAKNNAKVHAETTTQSSSLPYEEMKKILKSPDYPYRIECYDNAHLQGSHGVGVYIVYENDAFSPKSYRTFSISSLAHNDLATFHEVLSRRFSSLTSSLPDMIVIDGGRAQYSQAKKTLKELNLTGIQVVSLAKEASNHSSSLRNEKLFCDTFPQGIQLAPTSKLLQFFQKLRDEAHRFAISKHRRKRYKDLLFPQEKIPGIGEVKRKRLLQKFKSWKQVMKASQGELEAIPGLTKKDIQQLLAKQVEDSKLTED
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBSD_BACCR
Sequence: MKKHGVLNSEIAAVLASLGHTDTVVIADCGLPIPDGVKRIDLAVEIGKPSFLEVLQVVADDMAIEKVTLAEEVIINNAEVNKEIERKLIEPAFEYVSHEQFKEHTKKAKAIIRTGEATPYANVILHAGVIF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPG_RHIWR
Sequence: MPELPEVETTVRGLRPPLEGRRLTRVETRRADLRRPFPADLRQRMTGATITGLGRRAKYGLIETDRGDVMVFHLGMSGRWRIDPSEIGAHDHLVLETDEGRTLSLCDPRRFGSVDLVRGEELAGFGPFKALGPEPLGPDLTGAHLAGALEGRVAPIKAMLLDQRIVAGLGNIYVCEALHMTGIAPTTMAGRIAKKRLDRLVDSIREVLAAAIEAGGSTLRDYARPDGELGYFAKQWRVYGREGEPCHCGTVIRRRVDGGRSTFYCPKCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.