PharMolix/UniProtQA huggingface dataset:
Protein: IPYR_BUCBP
Sequence: MTLNTVLSGKNIPEDIYVIIEISAHSNPIKYEVNKDLGLLFVDRFIPVPMFYPCNYGFINKTKSNDGDPLDVLVHTPYPILPGSIIRCKPIGVLNMFDESGEDYKIIAIPHPKVCLEYSSINDICHLSPTLKQQIIHFFKHYKNLENNKWVKIIGWENKKNAEKIILSACEKFHK
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPPH_BURCM
Sequence: MLDREGFRPNVGIILLNARNEVFWGKRLREHSWQFPQGGIKYGETPMQAMYRELHEETGLHPEHVKIIGRTRDWLRYEVPDKFIKREVRGHYRGQKQIWFLLRMVGRDCDICLRATDHPEFDAWRWNEYWVPLDAVIEFKRDVYQLALTELSRFLRRPAQRADKPQGPRPSSRYPRVIGTQSQQTLTIVDTSVVCSEIEVEASTLDEMPPRVIVGK
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: PYRG_PSEPK
Sequence: MTRYIFVTGGVVSSLGKGIASASLAAILEARGLKVTMLKLDPYINVDPGTMSPFQHGEVFVTHDGAETDLDLGHYERFIRTTMTQNNNFTTGRIYEHVLRKERRGDYLGATIQVIPHITDEIKRRIIKGAGDADVALVEIGGTVGDIESQPFLEAIRQLRVEVGSKRAMLMHLTLVPYIATAGETKTKPTQHSVKELRSIGLQPDVLICRSDHPVDASSRRKIALFTNVEERAVISLEDVDTIYKIPGVLHAQGLDDFVVERFGLQCNGADLSEWDKVVDAKLNPEHEVTIAMVGKYMELLDAYKSLIEAMSHAGITNRTKVNLRYIDSEDIENQGTSLLEGADAILVPGGFGLRGVEGKITAVQYARENKVPYLGICLGMQVAVIEFARNVMGWKDANSTEFDRNSGHPVVGLITEWADATGAVETRDEASDLGGTMRLGAQDCQLAAGSKVHDCYGKDVITERHRHRYEVNNNLLPQLVEAGLVVSGRSEDGALVEVVESKDHPWFVACQFHPEFTSTPRDGHPLFSGFVKAALAQKNKA
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: NU6C_RANMC
Sequence: MDLPGPIHDFLLVFLGLGFIMGGLGVVLLTNPIFSAFSLGLVLVCTSLFYTPSNSHFVAAAQLLIYVGAINVLIIFAVMFMNGSEYYSDFHLWTVGDGVTSLVCTSIFVSLITTIPDTSWYGIVWTTRSNQIIEQDLINNSQQIGIHLSTDFFLPFELISIILLVALIGAISMARQY
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RBM3_MOUSE
Sequence: MSSEEGKLFVGGLNFNTDEQALEDHFSSFGPISEVVVVKDRETQRSRGFGFITFTNPEHASDAMRAMNGESLDGRQIRVDHAGKSARGSRGGAFGGRGRSYSRGGGDQGYGSGRYDSRPGGYGYGYGRSRDYSGSQGGYDRYSGGNYRDNYDN
What is the function of this protein?
Cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild hypothermic temperatures.  Reduces the relative abundance of microRNAs, when overexpressed.  Enhances phosphorylation of translation initiation factors and active polysome formation.
What are the official names of this protein?
RNA-binding protein 3, RNA-binding motif protein 3.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell projection, dendrite. Note=Localizes in mRNA granules in dentrites.
Protein: RDUF2_ARATH
Sequence: MPSTPTTPTTTTPITASYWCYSCTRFVSVWADQGTTTVGSVACPHCDGGFIEQINDSSSAATELTIPASTEVRSINNNRRSVIRRRRSGRRPSFNPVIVLQGGAGEREEGEEGDAARDRRAFEFYYDDGSGSGLRPLPDSVSEILMGSGFERLLEQLSQIEASATGIGRSGNPPASKSAIESLPRVEISDCHIGSEANCAVCTEIFETETEAREMPCKHLFHDDCIVPWLSIRNSCPVCRFELPSEPNRRSNNNEEDNAVGMTIWRLPGGGFAVGRFNAAMRDGERVLPVVLTEMDGGGIGNSQDGPRRISWVRSHGTLESDSNGTGSGSGSGGRLRRMVRGMVSLMRRVRPNRSSSSSSAAISTSSDNLDLNIEVESRVLDRSNSVMRRYFRRNRSNRDSSSSVLH
What is the function of this protein?
E3 ubiquitin-protein ligase involved in the positive regulation of abscisic acid-dependent drought stress responses.  Possesses E3 ubiquitin ligase activity in vitro.
What are the official names of this protein?
E3 ubiquitin-protein ligase RDUF2, RING and DUF1117 domain-containing protein 2, AtRDUF2, RING-type E3 ubiquitin transferase RDUF2.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RS2_METST
Sequence: MSELLIPLDKYLAAGLHIGTQQKTKDMEKYIYRVRADGLHVLDVKSSNDKIIVAAKLLSKYEPDDILVVSTRQYGQSPVKKFGEVTGTKTIPGRFIPGTLTNPQYAKFIEPKILVVTDPRSDSQAVIEAKQNGIPVVALCDTENLLCNVDVVIPVNNKGRKAIALVYWLLARQILRERGILSSDEEFDLEPTDFELKI
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: VG_DROME
Sequence: MAVSCPEVMYGAYYPYLYGRAGTSRSFYQYERFNQDLYSSSGVNLAASSSASGSSHSPCSPILPPSVSANAAAAVAAAAHNSAAAAVAVAANQASSSGGIGGGGLGGLGGLGGGPASGLLGSNVVPGSSSVGSVGLGMSPVLSGAAGHSLHSSHRTHAHSLAHAHTHPHSHTHTHTHQTKEEDLIVPRSEAEARLVGSQQHQHHNESSCSSGPDSPRHAHSHSHPLHGGGGATGGPSSAGGTGSGGGDGGGTGAIPKNLPALETPMGSGGGGLAGSGQGQAQYLSASCVVFTNYSGDTASQVDEHFSRALNYNNKDSKESSSPMSNRNFPPSFWNSNYVHPIPAPTHHQVSDLYGTATDTGYATDPWVPHAAHYGSYAHAAHAHAAHAHAYHHNMAQYGSLLRLPQQYASHGSRLHHDQQTAHALEYSSYPTMAGLEAQVAQVQESSKDLYWF
What is the function of this protein?
Involved in determining which thoracic imaginal disk cells will form wings and halteres, perhaps by interacting with other nuclear regulatory proteins.  When in combination with scalloped (sd), it acts as a transcriptional activation complex that regulates gene expression in the wing.  Binding to sd switches the DNA target selectivity of sd.  Required and sufficient for cell proliferation at the dorsal/ventral (D/V) boundary of the wing imaginal disk.  Also required for cell proliferation in the wing imaginal disk, mediated via activation of E2f.  By interacting with Dhfr, may control genes involved in DNA replication.
What are the official names of this protein?
Protein vestigial.
What are the subcellular locations of this protein?
Nucleus.
Protein: WDR90_HUMAN
Sequence: MARAWQHPFLNVFRHFRVDEWKRSAKQGDVAVVTDKTLKGAVYRIRGSVSAANYIQLPKSSTQSLGLTGRYLYVLFRPLPSKHFVIHLDVSSKDNQVIRVSFSNLFKEFKSTATWLQFPLVLEARTPQRDLVGLAPSGARWTCLQLDLQDVLLVYLNRCYGHLKSIRLCASLLVRNLYTSDLCFEPAISGAQWAKLPVTPMPREMAFPVPKGESWHDRYIHVRFPSESLKVPSKPIEKSCSPPEAVLLGPGPQPLPCPVASSKPVRFSVSPVVQTPSPTASGRAALAPRPFPEVSLSQERSDASNADGPGFHSLEPWAQLEASDIHTAAAGTHVLTHESAEVPVARTGSCEGFLPDPVLRLKGVIGFGGHGTRQALWTPDGAAVVYPCHAVIVVLLVDTGEQRFFLGHTDKVSALALDGSSSLLASAQARAPSVMRLWDFQTGRCLCLFRSPMHVVCSLSFSDSGALLCGVGKDHHGRTMVVAWGTGQVGLGGEVVVLAKAHTDFDVQAFRVTFFDETRMASCGQGSVRLWRLRGGVLRSCPVDLGEHHALQFTDLAFKQARDGCPEPSAAMLFVCSRSGHILEIDCQRMVVRHARRLLPTRTPGGPHPQKQTFSSGPGIAISSLSVSPAMCAVGSEDGFLRLWPLDFSSVLLEAEHEGPVSSVCVSPDGLRVLSATSSGHLGFLDTLSRVYHMLARSHTAPVLALAMEQRRGQLATVSQDRTVRIWDLATLQQLYDFTSSEDAPCAVTFHPTRPTFFCGFSSGAVRSFSLEAAEVLVEHTCHRGAVTGLTATPDGRLLFSSCSQGSLAQYSCADPQWHVLRVAADMVCPDAPASPSALAVSRDGRLLAFVGPSRCTVTVMGSASLDELLRVDIGTLDLASSRLDSAMAVCFGPAALGHLLVSTSSNRVVVLDAVSGRIIRELPGVHPEPCPSLTLSEDARFLLIAAGRTIKVWDYATQASPGPQVYIGHSEPVQAVAFSPDQQQVLSAGDAVFLWDVLAPTESDQSFPGAPPACKTGPGAGPLEDAASRASELPRQQVPKPCQASPPRLGVCARPPEGGDGARDTRNSGAPRTTYLASCKAFTPARVSCSPHSAKGTCPPPASGGWLRLKAVVGYSGNGRANMVWRPDTGFFAYTCGRLVVVEDLHSGAQQHWSGHSAEISTLALSHSAQVLASASGRSSTTAHCQIRVWDVSGGLCQHLIFPHSTTVLALAFSPDDRLLVTLGDHDGRTLALWGTATYDLVSSTRLPEPVHGVAFNPWDAGELTCVGQGTVTFWLLQQRGADISLQVRREPVPEAVGAGELTSLCYGAPPLLYCGTSSGQVCVWDTRAGRCFLSWEADDGGIGLLLFSGSRLVSGSSTGRLRLWAVGAVSELRCKGSGASSVFMEHELVLDGAVVSASFDDSVDMGVVGTTAGTLWFVSWAEGTSTRLISGHRSKVNEVVFSPGESHCATCSEDGSVRVWALASMELVIQFQVLNQSCLCLAWSPPCCGRPEQQRLAAGYGDGSLRIFSVSRTAMELKMHPHPVALTTVAFSTDGQTVLSGDKDGLVAVSHPCTGTTFRVLSDHQGAPISTICVTCKECEDLGVEGTDLWLAASGDQRVSVWASDWLRNHCELVDWLSFPMPATTETQGHLPPSLAAFCPWDGALLMYVGPGVYKEVIIYNLCQKQVVEKIPLPFFAMSLSLSPGTHLLAVGFAECMLRLVDCAMGTAQDFAGHDNAVHLCRFTPSARLLFTAARNEILVWEVPGL
What is the function of this protein?
Required for efficient primary cilium formation.
What are the official names of this protein?
WD repeat-containing protein 90.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR90/POC16 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
Protein: MRAY_BART1
Sequence: MMLFFSSFSDWFPGVNVFRYITFRTIAAMLTSGLIVFLFGPSIIASLKLRQGKGQPIRADGPQTHFKKAGTPTMGGLMILTGIVVSAFLWCNLSNIYFWVSLLVMLSFGAIGFYDDYLKVTKQTDKGFSGKARLSLEFFVAAIAAFIILQIGSSGFALPFLKDYLIHLGWFFIPFSAFVIVATGNAVNLTDGLDGLAIVPVMVAALSFALIAYLCGNMNFADYLQIHYVSGTGELAVLLGAVVGAGLGFLWFNAPPAAIFMGDTGSLALGGLLGTVAVATKHEIVLVLIGGLFVVEAFSVVIQVGYFKLTRKRVFLMAPIHHHFEKKGWTESQVVIRFWIISIVLALIGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MIAA_LEGPH
Sequence: MNKLVFCLMGPTASGKTGLACELLTHFPFEIISVDSAMIYRDMNIGTAKPSIHELQRAPHYLIDIKDPVESYSAAQFCTDALSLCAEIIKRGNIPLLVGGTMMYFNALQKGLATLPEADEAVRKRLEEEALSQGWDFLYQKLSQLDPVTAARIHAHDTQRIQRALEVYYLTGSTLSTYLTGPHERPDYYFVNLALFPEQRSWLHERIAQRFDAMLSEGFIEEVQQLQAKWPIQINLPSMRCVGYRQILQHLAGHYDYETMREKGIAATRQLAKRQLTWLRHWEGALFYDSQNVGFNTDIIAKIREILDNTVSN
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: HIS8_LEUCK
Sequence: MKETIKNMAAYEAELPVAEVKATYGVSHVARLSANESPYGPSPKVGPAIRDVSDDVLGFYPDGQATALRQAVAKLEQVNPDSLVFGAGADELIELLTRVILTPNDNVIVPNPTFGEYAMHAQIEQATTKSIPVNQDTGHVDFDAMFDAVDEHTTMVWLANPNNPTGVFETRSDILSFLQKLPQSVVLVVDEAYYDFVDQIDATVIRDVKDYPNLVVLRTLSKAYGLANLRIGYGVMQEPLYQVMQAVRLPYNLNTYQITGAVAALSDQLYLQSVVAKVKSEREKFEQFLTKHQFKYYQSQTNFLWIKVGDAKRVGEALLSEGYQINDRLNAEWIRIALGTVSDNEGMQRILLNF
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: AROQ_JANSC
Sequence: MKISVFNGPNLNALGTREPGIYGADTLADIEAACRTTAADLGVDLDFLQTNQEGALVDAFHAARDTSDGVVINAGAYTHTSIALRDAISATELPTVELHLSNTHAREAFRHHSMIAPVCVGLILGFGAYGYPLAVTALVQHLKQGNAP
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: PDXJ_RUEPO
Sequence: MSVPHLRLGVNIDHVATVRNARGGEYPDPIRAAKIAEQAGADGITAHLREDRRHITDADIDGLMAALSVPLNFEMAATDEMQKIALRHKPHAVCIVPEKREERTTEGGLEVAREENRLAHFIAPLREVGCRVSIFIAADRRQVEAAHRIGAQVIELHTGAYCDAHAEGDFATRDRELEALREMSAFAHSLGLEVHAGHGLTYDTVQPVAAFPEVMELNIGHFLIGEAIFRGLHPAIAEMRRLMDEARA
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLIC_GLOVI
Sequence: MFPTGWRPKLSESIAASRMLWQPMAAVAVVQIGLLWFSPPVWGQDMVSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVENARDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQTLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILPMLFILFISWTAFWSTSYEANVTLVVSTLIAHIAFNILVETNLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVFLLANIILAFLFFGF
What is the function of this protein?
Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side.  Displays no permeability for chloride ions.  Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS.  Might contribute to adaptation to external pH change.
What are the official names of this protein?
Proton-gated ion channel, GLIC, Ligand-gated ion channel, LGIC.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GNAI_HOMAM
Sequence: MGCAMSNAADKEAAERSKKIDKDLRLAGERAAREVKLLLLGAGESGKSTIVKQMKIIHETGYSREECEQYRPVVYSNTIQSLMAIIRAMGQLKIDFRDSSRADDARHFFTLASAADEGELTPELANIMKRLWNESGVQHCRNRSREYQLNDTAAYYLNALDRIARPGYIPTQQDVLRTRVKTTGIVETNFSFKNLNFKLFDVGGQRSERKKWIHCFEGVTAIIFVVALSGYDLVLAEDEEMNRMIESMKLFDSICNNKWFVETSIILFLNKKDLFEQKITKSPLTICFPEYQGSNVYEDSANYIRMKFENLNKRKDQKEIYTHFTCATDTNNIQFVFDAVTDVIIKNNLKDCGLF
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
What are the official names of this protein?
Guanine nucleotide-binding protein G(i) subunit alpha, Adenylate cyclase-inhibiting G alpha protein.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(i/o/t/z) subfamily.
Protein: PDXJ_XYLFA
Sequence: MSQRTRLSVNVNKIAVLRNSRGDGAPDVIRAASACIDAGAHGITVHPRPDARHIRHDDVIGLSALTRARGVEFNIEGNPFAEPRAGYCGLLALCRETRPHQVTLVPDGDQQITSDHGFDFAREGPGLRPLIDEIKQWGCRVSLFVDVNVTGLADAAIWGVDRIELYTGPYAEMHHAGCSDAVLREFATTARLAQDVGLGVNAGHDLSQTNLGVFLGAVPDVLEVSIGHALISEALYEGLVPTVRRYLDILDSVNPAVSMR
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURI_STACT
Sequence: MNKPIGVIDSGVGGLTVAKEIIRQLPNETIYYLGDSARCPYGPREGDEVRKFTVQLAQKLMEFDIKMLVIACNTATAVALDTLKELLPIPVIGVIEPGSRTAIMTTKNNNVMVLGTEGTIKSEAYTKHIKAINPHVDVTGVACPDFVPLVEQMRYHDPVPTNIVIHQTLKNYRTNKADTVILGCTHYPLLFEPLHDYFGGSKTVISSGLETAREVSALLTFSNEHAPYTPNTKHRFFATGDTEHIEYIISQWLKIDDVEVTQVKVD
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: PG115_VACCW
Sequence: MDIFIVKDNKYPKVDNDDNEVFILLGNHNDFIRLKLTKLKEHVFFSEYIVTPDTYGSLCVELNGSSFQHGGRYIEVEEFIDAGRQVRWCSTSNHISKDIPEDMHTDKFVIYDIYTFDAFKNKRLVFVQVPPSLGDDSHLTNPLLSPYYRNSVARQMVNDMIFNQDSFLKYLLEHLIRSHYRVSKHITIVRYKDTEELNLTRICYNRDKFKAFVFAWFNGVSENEKVLDTYKKVSNLI
What is the function of this protein?
Late protein which is part of a large complex required for early virion morphogenesis.  This complex participates in the formation of virosomes and the incorporation of virosomal contents into nascent immature virions.
What are the official names of this protein?
Core protein OPG115, 27 kDa virion core protein.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG115 family.
Protein: LEU1_SALPC
Sequence: MSQQVIIFDTTLRDGEQALQASLSAKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQTIARTIKNSRVCALARCVEKDIDVAAQALKVADAFRIHTFIATSPMHIATKLRSTLDEVIERAVYMIKRARNYTDDVEFSCEDAGRTPVDDLARVVEAAINAGARTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGIAVGNSLAAVHAGARQVEGAMNGIGERAGNCALEEVIMAIKVRKDIMNVHTNINHHEIWRTSQTVSQICNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMEEMGYKDTDYNMDHLYDAFLKLADKKGQVFDYDLEALAFINKQQEEPEHFRLDYFSVQSGSSDIATASVKLACGEEIKAEAANGNGPVDAIYQAINRITGYDVELVKYDLNAKGQGKDALGQVDIVVNHHGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQNKENNKETV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: DLDH1_PSEPU
Sequence: MQQTIQTTLLIIGGGPGGYVAAIRAGQLGIPTVLVEGQALGGTCLNIGCIPSKALIHVAEQFHQASRFTEPSPLGISVASPRLDIGQSVAWKDGIVDRLTTGVAALLKKHGVKVVHGWAKVLDGKQVEVDGQRIQCEHLLLATGSSSVELPMLPLGGPVISSTEALAPKALPQHLVVVGGGYIGLELGIAYRKLGAQVSVVEARERILPTYDSELTAPVAESLKKLGIALHLGHSVEGYENGCLLANDGKGGQLRLEADRVLVAVGRRPRTKGFNLECLDLKMNGAAIAIDERCQTSMHNVWAIGDVAGEPMLAHRAMAQGEMVAEIIAGKARRFEPAAIAAVCFTDPEVVVVGKTPEQASQQGLDCIVAQFPFAANGRAMSLESKSGFVRVVARRDNHLILGWQAVGVAVSELSTAFAQSLEMGACLEDVAGTIHAHPTLGEAVQEAALRALGHALHI
What is the function of this protein?
The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2).  It contains multiple copies of 3 enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
What are the official names of this protein?
Dihydrolipoyl dehydrogenase, Dihydrolipoamide dehydrogenase, E3 component of branched-chain alpha-keto acid dehydrogenase complex, LPD-Val.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSIV_BACSU
Sequence: MDKRLQQLREEYKNVQIPKELDIIVEKALQQEPKKKRIVMWPTSAAIAAAILFTALVNINPDAAQAMSKIPVIGKIVKAITFIEIKEEKDQSSIDVKTPALSGLSNKELENSINEKYLKESQQLYKEFIQSTSKNKKGHLSIYSDYETVTDTPDLLSIRRNIETTQASSYTQSRYITIDKKNDILLTLKSLFKDERYIKVISQNIKEQMKQQMKEDPNKIYWLTDEDAEPFKTILPDQTFYITEDHKLVISFDEYEVAPGYMGVTEFTIPTGVISNLLVGERYIR
What is the function of this protein?
Anti-sigma factor for SigV.  Negatively regulates SigV activity through direct interaction.
What are the official names of this protein?
Anti-sigma-V factor RsiV.
What is the protein family that this protein belongs to?
Belongs to the RsiV family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SC5A5_MOUSE
Sequence: MEGAEAGARATFGPWDYGVFATMLLVSTGIGLWVGLARGGQRSADDFFTGGRQLAAVPVGLSLAASFMSAVQVLGVPAEAARYGLKFLWMCVGQLLNSLLTALLFLPIFYRLGLTSTYQYLELRFSRAVRLCGTLQYLVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTLYTTVGGMKAVVWTDVFQVVVMLVGFWVILARGVMLMGGPWNVLSLAQNHSRINLMDFDPDPRSRYTFWTFVVGGSLVWLSMYGVNQAQVQRYVACHTERKAKLALLVNQLGLFLIVASAACCGIVMFVYYKDCDPLLTGRIAAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRMPSLAPRKLVFISKGLSFIYGSTCLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAFTLGMLLPACNTPGVLSGLTAGLAVSLWVAVGATLYPPGEQTMGVLPTSAAGCTNASVLPSPPGAANTSRGIPSSGMDSGRPAFADTFYAVSYLYYGALGTLTTMLCGALISYLTGPTKRSSLGPGLLWWDLARQTASVAPKEDTTTLEDSLVKGPEDIPAATKKPPGFRPEAETHPLYLGHDVETNL
What is the function of this protein?
Sodium:iodide symporter that mediates the transport of iodide into the thyroid gland (PubMed:11716040, PubMed:18372236, PubMed:32084174).  Can also mediate the transport of chlorate, thiocynate, nitrate and selenocynate (By similarity).
What are the official names of this protein?
Sodium/iodide cotransporter, Na(+)/I(-) cotransporter, Sodium-iodide symporter, Na(+)/I(-) symporter, Solute carrier family 5 member 5.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NOP58_CANGA
Sequence: MSYVLTETSAGYALLKASDKKIYKSSSLIMDLDSSEKVLKEFKIAAFSKFNSAANALEEASAIIEGKVSPQLEKLLDEIKKEKKATLIVSETKLANAINKLGLNFNVVSDAVTLDIYRAVKEYLPDLLPGMSDSDLSKMSLGLAHSIGRHKLKFSADKVDVMIIQAIALLDDLDKEVNTYSMRCKEWYGWHFPELAKIVTDSVAYARLILTMGVRSKAAETDMSEILPEEIEERVKAAAEVSMGTEITDVDLINIRALADQIVEFAAYREQLSNYLSSRMKAIAPNLTQLVGELVGARLIAHAGSLISLAKSPASTIQILGAEKALFRALKTKHDTPKYGLLYHASLVGQASGRNKGKIARVLAAKAAVALRYDALAEDRDDSGDIGLEVRAKVENRLSQIEGRDLRTTPKVVREAKKVEMTEARAYNADADTAAAADSDDEDEETEEKADKKRKRDTEEEEEEEETESKKSKKEKKEKKEKKDKKEKKEKKEKKDKKEKKEKKEKKEKKSKK
What is the function of this protein?
Required for pre-18S rRNA processing.  May bind microtubules (By similarity).
What are the official names of this protein?
Nucleolar protein 58.
What is the protein family that this protein belongs to?
Belongs to the NOP5/NOP56 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RT4I1_DANRE
Sequence: MLMCRRWLVCSLRCHYRSFSFSAARRTVMPAWVIDKYGKNDVLRFTKNAALPIIHYPNEVVVKVHAAGLNPIDISMRGGYGAATMAMKRDPLNISQSGGEFPLILGRDVSGEIMECGLDVKYFKPGDQVWAAIPPWKQGSLAEFVVVSGNEVSHKPKSLRHDEAASIPYVAATAWSAIVNTGGLNKDNSAKKRVLILGGSGGVGTFAIQMVKAWGAHVTVTCSQNAERLVRDLGADDVVDYTAGPVEKQLKNLEKFDLILDSIGGETEKWALDLLKPWSGAKFVTLITPFLQNTDRLGLADGMMQSAVTVGCKVVKNLRKGVHYRWGFFAPSGSALDEVSEMVDAGKVRPVVEEVFSFAQVPEAFQKVEQGHARGKTVVSIMEDQKE
What is the function of this protein?
Plays a role in the regulation of retinal ganglion cell (RGC) maturation, neurite outgrowth, and hence in the development of the inner retina and optic nerve (PubMed:26593267).  Appears to be a potent inhibitor of regeneration following spinal cord injury (By similarity).
What are the official names of this protein?
Reticulon-4-interacting protein 1 homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: RL20_SALTY
Sequence: MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFDKVAFTALVEKAKAALA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit (By similarity).
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RS3A_THEON
Sequence: MAKGNPRKRAAATKDKWKMKEWYVVYAPDFFGNKEIGLTPADDPEKVIGRVIETTLKDLTGDFTKGQVKLYFQIYDVKGQNAYTKFKGHTLSRSYIRSLVRRRTTRVDGIFNITTKDGYKLRVMGMVIAYRRIQTSQERAIREIMRDIIYKKAEELNYKDFILEAVTGKMATEIAKEARKIYPIKRAEIRKIKVLAEPEA
What are the official names of this protein?
30S ribosomal protein S3Ae, Ribosomal protein S1e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.