PharMolix/UniProtQA huggingface dataset:
Protein: KIF23_HUMAN
Sequence: MKSARAKTPRKPTVKKGSQTNLKDPVGVYCRVRPLGFPDQECCIEVINNTTVQLHTPEGYRLNRNGDYKETQYSFKQVFGTHTTQKELFDVVANPLVNDLIHGKNGLLFTYGVTGSGKTHTMTGSPGEGGLLPRCLDMIFNSIGSFQAKRYVFKSNDRNSMDIQCEVDALLERQKREAMPNPKTSSSKRQVDPEFADMITVQEFCKAEEVDEDSVYGVFVSYIEIYNNYIYDLLEEVPFDPIKPKPPQSKLLREDKNHNMYVAGCTEVEVKSTEEAFEVFWRGQKKRRIANTHLNRESSRSHSVFNIKLVQAPLDADGDNVLQEKEQITISQLSLVDLAGSERTNRTRAEGNRLREAGNINQSLMTLRTCMDVLRENQMYGTNKMVPYRDSKLTHLFKNYFDGEGKVRMIVCVNPKAEDYEENLQVMRFAEVTQEVEVARPVDKAICGLTPGRRYRNQPRGPVGNEPLVTDVVLQSFPPLPSCEILDINDEQTLPRLIEALEKRHNLRQMMIDEFNKQSNAFKALLQEFDNAVLSKENHMQGKLNEKEKMISGQKLEIERLEKKNKTLEYKIEILEKTTTIYEEDKRNLQQELETQNQKLQRQFSDKRRLEARLQGMVTETTMKWEKECERRVAAKQLEMQNKLWVKDEKLKQLKAIVTEPKTEKPERPSRERDREKVTQRSVSPSPVPLSSNYIAQISNGQQLMSQPQLHRRSNSCSSISVASCISEWEQKIPTYNTPLKVTSIARRRQQEPGQSKTCIVSDRRRGMYWTEGREVVPTFRNEIEIEEDHCGRLLFQPDQNAPPIRLRHRRSRSAGDRWVDHKPASNMQTETVMQPHVPHAITVSVANEKALAKCEKYMLTHQELASDGEIETKLIKGDIYKTRGGGQSVQFTDIETLKQESPNGSRKRRSSTVAPAQPDGAESEWTDVETRCSVAVEMRAGSQLGPGYQHHAQPKRKKP
What is the function of this protein?
Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis.  Essential for cytokinesis in Rho-mediated signaling.  Required for the localization of ECT2 to the central spindle.  Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro.
What are the official names of this protein?
Kinesin-like protein KIF23, Kinesin-like protein 5, Mitotic kinesin-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Midbody, Midbody ring. Note=Localizes to the interzone of mitotic spindles. Detected at the midbody during later stages of mitotic cytokinesis.
Protein: RL14_MYCTA
Sequence: MIQQESRLKVADNTGAKEILCIRVLGGSSRRYAGIGDVIVATVKDAIPGGNVKRGDVVKAVVVRTVKERRRPDGSYIKFDENAAVIIKPDNDPRGTRIFGPVGRELREKRFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RPOC_SACD2
Sequence: MKDLLNLLKNQGPSDEFDGIRIGLASPDMIRSWSYGEVKKPETINYRTFKPEREGLFCAKVFGPVKDYECLCGKYKRMKHRGIICEKCGVEVTLAKVRRDRMAHIELASPVAHIWFLKSLPSRIGLLLDMTLRSIERVLYFESYVVTDPGMTTLEKGQLLTDEQYFEAMEEFGDEFEAKMGAEAIQQLMKDIELEREAQEIREQIPNTNSETKIKKLSKRLKLLEAFIQSGNKPEWMVLEALPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLNAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVIVTGPTLRLHQCGLPKKMALELFKPFIFSKLELRGLATTIKAAKKMVEREEPVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPASGEPIIVPSQDVVLGLYWMTRERVNDKGEGMIFSDIKEVSRAFYSKQVGLQARIKVRIDETIMEESGESESSYRMVDTTVGRMLLWEIVPKGIPFEMINKPMVKKAISAVINFCYRIVGLKATVIFADQLMYMGYDFSTKSGSSIGVNDFEIPEAKAGMIERADAEVKEIEAQYASGLVAQGEKYNKVIDIWSRANDLVAKSMMEGISKETVKNKQGEDEEQASFNSVFMYADSGARGSPAQIRQLAGMRGLMARPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDVVITEQDCGTDEGLSMTPVIEGGDVIESLGDRILGRVVARDVIRPNSDEILVPAGTMIDEKWVERIESMGIDEVTVRSAISCDAVFGICAQCYGRDLARGHRANVGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRASAADSVEVKQEGTVRLHNIKVVARESGELIAVSRSGELALADAAGRERERYKIPYGAVITVKEGEQVKGGSIIAKWDPHTHPIVTEVAGRVVLAGMEDGLSIRKQTDELTGLTTIEILDPSERPSAGKDLKPAVTLVDENGNELKLANSEQPAHYMLPGKSIFSLKNGDTVGVGDIIARIPQEGSKTRDITGGLPRVADLFEARKPKEPSILAEISGTVSFGKETKGKRRLVITPPNGAVLEDGSTHYEVLIPKHRHLTVFEGETVAKGEVVSDGPSNPHDILRLKGVEALANYITNEIQDVYRLQGVKINDKHVEVIVRQMLRKVEITGMGDSSFVKGEQVEYIAVLQENEKLRAEGRQPARFERQLLGITKASLATESFISAASFQETTRVLTEASVTGKIDNLRGLKENVVVGRLIPAGTGLAYHAERRRKREDQAGSKAGSDTVSAAEIEAALTEALKSSAS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: R1C3_SOLDE
Sequence: MYFNNELSNLKDHLLVTLQNNSDVERDRINFILWDLKFLDCFLHLKRLPFASECGMLEFSQKMIEIWKIQSHREPYDCPYWKEVIWKTKQEFRAEYSFPNTSLAANKVDDVSPKFVMEVIDVFVENLNVVVKINDPYSWLFVPEHKEQIEQVLKELKLLRFFVCFVSNKCIEPQYRHTTFYIHALIEASHIAMVVWLHLPVLNGIVNQYLAPSEVSRLRSDFMEMKIKSIQPDISRNNIYIDVLQALKSTIPQAQNKHAVESGIVETPTQNLTVGLSDQMVNLQEMLCFLRDNLIHLPILDLEFHLQDMDSVIVDAGLLIYSLYDIKGEKEDTVLDNMNRALGFDLPRNIEPIKAMVYLVMQKAFQSNLPRVHGLGYVDFLLKNLKDFQGRYSDSLAFLKNQLQVIQTKFESMQPFLKVVVEEPHNKLKTLNEDYATQIIRKAYEVEYVVDACINKEVPQWCIERWLLDIIEEITCIKAKIQEKNTVEDTMKSVIASSQLARTPRMNEEIVGFEDVIETLRKKLLNGTKGQDVISMHGMPGLGKTTLANRLYSDRSVVSQFDICAQCCVSQVYSYKDLLLALLRDAIGEGSVRTELHANELADMLRKTLLPRRYLILVDDVWENSVWDDLSGCFPDVNNRSRIILTTRHHEVAKYASVHSDPLHLRMFDEVESWKLLEKKVFGEESCSPLLRDIGQRIAKMCGQLPLSIVLVAGILSEMEKEVEYWEQVANNLGTHIHNDSRAVVDQSYHVLPCHLKSCFLYFGAFLEDRVIDISRLIRLWISESFVKSCEGRSLEDIAEGYLENLIGRNLVMVTQRDDSDGKVKACRLHDVLLDFCKERAAEENFLLWINRDQITKPSSCVYSHNQHAHLAFTDMKNLVEWSASCSRVGSVLFKNYDPYFAGRPLSSHAFSISRILLNFKFLKVLDLEHQVVIDSIPTELFYLRYISAHIEQNSIPSSISNLWNLETLILNRTSAATGKTLLLPSTVWDMVKLRHLHIPKFSPENKKALLKKSARLDDLETLFNPYFTRVEDAELMLRKTPNLRKLICEVQCLEYPHQYHVLNFPIRLEMLKLHQSNIFNPISFCISAPNLKYLELSGFYLDSQYLSETADHLKHLEVLKLYYVEFGDHREWKVSNGMFPQLKILKLKCVSLLKWIVADDAFPNLEQLVLRGCRHLMEIPSCFMDILSLQYIEVENCNESVVKSAMNIQETQVEDNQNTNFKLILIEIHLFYLFDMKGIESISTDMKEKKLTVTRDVDADEVQLVVEKLRNVAYADEVQLVVEKLRKRGML
What is the function of this protein?
Confers resistance to late blight (Phytophthora infestans) races carrying the avirulence gene Avr1.  Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein.  That triggers a defense system including the hypersensitive response, which restricts the pathogen growth.
What are the official names of this protein?
Putative late blight resistance protein homolog R1C-3.
What is the protein family that this protein belongs to?
Belongs to the disease resistance NB-LRR family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: Y920_METJA
Sequence: MQDKEFKIAIIGPENAGKSSIMNALFGKYVSLVSEVGGTTKMPIKRYWGKLKIGRIKEEPEFVNLVFVDLGGLYTTTDKQSPIMTPKVLEKTFEEINDSDMIIHVIDGSVGLLRSFERLHHLLKFRYQKPIIVVINKCDLLNDSDKEHLKNYVERRIKNTPIFVSAKTFEGIPELLDIIIKYLKR
What are the official names of this protein?
Uncharacterized protein MJ0920.
Protein: SCX7_TITCO
Sequence: KEGYAMDHEGCKLSCFIRPSGYCGRECGYKKGSSGYCAWPACYCYGLPNWVKVWERATNRCGKK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Toxin Tco-gamma, T-beta* NaTx6.4, Toxin gamma-like.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PLSB_ALISL
Sequence: MSTGQTIYHSLLKLPLSVMVKSTPIPSNPIEDLNIDIERPIIYALPFRSHVDLLTLQKSAKELGLPDPLSPIEIDGVSYPRYVFTSIGPKMFDTDDDLPQESLDLFKIVLKHHADNPDADFQLIPTSILWGRRPGKEGTSRPHLMPLNGPQKFVTLIKAGRDSTVRISPVVSLRYMADNHGADDAIAHKLARVAKIHFSRQKLAASGPNLPNRQALFNRLLKSQAIEKVILEEARIRNVDVEKVRKEAMGIMEEIATNFSYSLIKNGNRILKWLWNRLYQGLNINNAATVRKLAQEGHEIVYVPCHRSHMDYLLLSYVLYHEGLVPPHIAAGINLNFFPAGPIFRRGGAFFIRRSFKGNRLYSTIFREYLAELFAKGYSVEYFSEGGRSRTGRLLQAKTGMLAMTVQAMLRGLNRPVTLVPVYIGYEHVMEVTTYAKELQGKRKEKENAGQVLRTLRKLRNFGQGYVNFGEPISLNHYLNEHAPNWSESINPIEPQKPEWMSPVVNGIANKMMTHINDAVAANALTLCATALLAARQRALSKEDLTEQLDCYLQLLRNIPYSNTATVPTQDAEALLEHAIALDKFVIEKDTLGEIISLDRNQSILMTYYRNNIIHLFALPSLIAKLVVQYRSISIDNVQAQIQQIYPFLKAELFLHYDESELNDVVSQHIDELVRQKLIERENDVLQLNATNILKVHLLAHTISETLQRYAIALTHLQASPKLGKNDLEEQSQIMAQRLSRLHGINAPEFFDKGVFGILFNTLKAEGYLNSDGVAVISKVEPFSRDMSRLLNPEIKLTIQAVMTKED
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: IOLB_HALH5
Sequence: MSQLLRKPERAEISKGVTLVHDVTADNASLEYVSFKALDLSQGATYSETLENKECCIVVVTGKVHVTDHEVTFENIGTRESVFEKKPTDSVYVSNNQTFSIEAVTGARVALCYAPSKNQLPTKLIKAEDNGVEHRGKGNNQRMVHNILPDSDPSANSLLVVEVFTESGNWSSYPPHKHDRDLLPEESLLEETYYHEVNPKQGFVFQRVYTDDRSLDETMTVENENMVIVPKGYHPVGVPEGYASYYLNVMAGPKRIWKFFNDPAHEWIIE
What is the function of this protein?
Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D-gluconate).
What are the official names of this protein?
5-deoxy-glucuronate isomerase, 5DG isomerase.
What is the protein family that this protein belongs to?
Belongs to the isomerase IolB family.
Protein: ACTD_PHYPO
Sequence: MEGEAVVIDNGSGMCKAGFAGDNTPRAMFPSIVGHPRHTEAMMEIGHKHSYVGDEAQSKRGILALKYPIEQGIVNNWDDMEQIWHHTFYNEMRVAPEEHPVLLTEAPLNPKANREKMTQIMFESFSAPAMYVAIQAVLSLRASGRTTGIVLDSGDGASHAVPIYEGCALPHAILRIDAAGRDLTHYLRLMLAERGYAFNTTAELEIVRDIKEKLAYVALDFEQEMQTASSLNYELPDGRVVTIGNERFRCSEVLFQSCFLGMESAGIPETTYNSIMKCDVDIRKDLFGNLVLSGGTTMVPGIADRVQKELTAFEPTMKIKIIAPPGRQYSAWIGGSILASLSTFEQMCISKKEYNECGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin, spherule isoform.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: KCMB3_HUMAN
Sequence: MDFSPSSELGFHFVAFILLTRHRTAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQFKLCIMRRSKGRAEKS
What is the function of this protein?
Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel.  Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.  Alters the functional properties of the current expressed by the KCNMA1 channel.  Isoform 2, isoform 3 and isoform 4 partially inactivate the current of KCNBMA.  Isoform 4 induces a fast and incomplete inactivation of KCNMA1 channel that is detectable only at large depolarizations.  In contrast, isoform 1 does not induce detectable inactivation of KCNMA1.  Two or more subunits of KCNMB3 are required to block the KCNMA1 tetramer.
What are the official names of this protein?
Calcium-activated potassium channel subunit beta-3, BK channel subunit beta-3, BKbeta3, Hbeta3, Calcium-activated potassium channel, subfamily M subunit beta-3, Charybdotoxin receptor subunit beta-3, K(VCA)beta-3, Maxi K channel subunit beta-3, Slo-beta-3.
What is the protein family that this protein belongs to?
Belongs to the KCNMB (TC 8.A.14.1) family. KCNMB3 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BRE1A_MOUSE
Sequence: MSGIGNKRAAGEPGTSMPPEKKTAVEDSGTTVETIKLGGVSSTEELDIRTLQSKNRKLAEMLDQRQAIEDELREHIEKLERRQATDDASLLIVNRYWSQFDENIRIILKRYDLDQGLGDLLTERKALVVPEPEPDSDSNQERKDDRERGDGQEPAFSFLATLASSSSEEMESQLQERVESSRRAVSQIVTVYDKLQEKVDLLSRKLNSGDNLIVEEAVQELNSFLAQENVRLQELTDLLQEKHHTMSQEFCKLQGKVETAESRVSVLESMIDDLQWDIDKIRKREQRLNRHLAEVLERVNSKGYKVYGAGSSLYGGTITINARKFEEMNAELEENKELAQNRHCELEKLRQDFEEVTTQNEKLKVELRSAVEEVVKETPEYRCMQSQFSVLYNESLQLKAHLDEARTLLHGTRGTHQRQVELIERDEVSLHKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQTLAANEQAGPINREMRHLISSLQNHNHQLKGEVLRYKRKLREAQSDLNKTRLRSGSALLQSQSSTEDPKDEPTELKQDSEDLATHSSALKASQEDEVKSKRDEEERERERREKEREREREREKEKEREREKQKLKESEKERDSVKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMKLLLDMYRSAPKEQRDKVQLMAAEKKSKAELEDLRQRLKDLEDKEKKENKKMADEDALRKIRAVEEQIEYLQKKLAMAKQEEEALLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFKLMSERIKSNQIHKLLKEEKEELADQVLTLKTQVDAQLQVVRKLEEKEHLLQSNIGTGEKELGLRTQALEMNKRKAMEAAQLADDLKAQLELAQKKLHDFQDEIVENSVTKEKDLFNFKRAQEDISRLRRKLETTKKPDNVPKCDEILMEEIKDYKARLTCPCCNMRKKDAVLTKCFHVFCFECVKTRYDTRQRKCPKCNAAFGANDFHRIYIG
What is the function of this protein?
Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1).  H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively).  It thereby plays a central role in histone code and gene regulation.  The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports about the cooperation with UBE2E1/UBCH are contradictory.  Required for transcriptional activation of Hox genes.  Recruited to the MDM2 promoter, probably by being recruited by p53/TP53, and thereby acts as a transcriptional coactivator.  Mediates the polyubiquitination of PA2G4 leading to its proteasome-mediated degradation.
What are the official names of this protein?
E3 ubiquitin-protein ligase BRE1A, BRE1-A, RING finger protein 20, RING-type E3 ubiquitin transferase BRE1A.
What is the protein family that this protein belongs to?
Belongs to the BRE1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BR1E_PELSA
Sequence: FLPLLAGLAANFLPKIFCKITRKC
What is the function of this protein?
Antimicrobial peptide (By similarity).  Stimulates insulin release by BRIN-BD11 cells in vitro.
What are the official names of this protein?
Brevinin-1E.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GCH1_ECO5E
Sequence: MPSLSKEAALVHEALVARGLETPLRPPVHEMDNETRKSLIAGHMTEIMQLLNLDLADDSLMETPHRIAKMYVDEIFSGLDYANFPKITLIENKMKVDEMVTVRDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQILIALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRHEFLRAVRHHN
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: FORI_DICDI
Sequence: MHDIDVAIQINMLFLPPTNELIRVDSNSKQLNQPQQQQQQQQQQINNENENSINNQENKENNNKDNNNNNNKEIKQSSEWGSKFSSLFSNMTKKKKSNFDLEMDAIKDAFLLNKPINNEEGLLIYSLDKSKKYIHSLSELDIGYVYLTEKETPIIRQNEDEVILANKVIIQANTMKRFSIKGILQSDVTTNALEIFTKRKMSQGVLFLEEDGSLCRIFYKIQDLITDTIYCNQDDTVMLQKLPNNEGIRFRFRGSFNREQVQQAMLAFSQPSDPQTWKRTIILREQQHHSSQSFTGDSVASRFLNKLSSKTKEDEESNDLKTKRENTVLKLKNRMKIDWDWKYTSTSVPIDQEPPTFIDNMVNRVREKISGSNNKLSDLLSSAKKQPQQQPQKDVTSSSSSSSNSSSPYLDSVDKLVITTNDSSSSNPLPDFDKLSLSSDDKVNNNNVQIENTTPSVPPPPPVGAPPPPPPPPPPPPPPPPSTLKLNRNRISTPKKPNNSGGGGGGGQLTPLQKKMRQLHWNAIPREKLKETFWDNLSPVKGNDNDQTLVESWFSLSPMAKEKMSKENLNNSNNNNNNNSNNNGEEQSLSDSGNTIVISKIIILDLRRSNNICILLSQFKLSYGAIKEAILCFEDGKLSVEQLIALDAMLPISEEEYQSLSSANYQSIEQLGNAERFLIEMMSIQHLQQRVQTYLFKLEVCSLLDSIEINNNQLSKAIEQLRNSRKFIKVLKVIFHIGSILNRGTYLNSTKGFKLDSLSKLSETKSKDQKHTVVDFIEIYIRENQPELLNFYSELDLLDKIPQSSLENILEESNEIENKFKQVDQEIQYHQQLLTNDNNNTLSSSSSSSYDQSKDTYLKVMSPFYDTFNTRFITIKQSTQQTLKQFQECCIYFGEDPQNITSKDFFSNIVKFSIAFKSSSNNAKKSLNLSTLNSK
What is the function of this protein?
Formins play an important role in the nucleation of actin and the formation of linear actin filaments.
What are the official names of this protein?
Formin-I.
What is the protein family that this protein belongs to?
Belongs to the formin homology family. Diaphanous subfamily.
Protein: CSRA_SHIF8
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQAEKSQQSSY
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
Protein: CAPP_PROMS
Sequence: MESFRQVKNNNVDLISNNDPLDKNRLLIEDLWESVLREECPDDQAERLIQLKELSYSKQIDGDSSKTFKNEIVDIVNSMDLAESIAAARAFSLYFQLVNILEQRVEEDRYIQSFTNKDVQKSPDNLDPFAPALARQNAPVTFRELFYRLRKLNVPPGKLEELLQEMDIRLVFTAHPTEIVRHTIRHKQTRVANLLKKIQIEQFLTKEEKNSLKTQLKEEVRLWWRTDELHQFKPSVLDEVDYALHYFQQVLFNAMPQLRGRIAEALTDNYPDVQLPSESFCNFGSWVGSDRDGNPSVTPEITWRTACYQRQLMLERYIIATSNLRDQLSVSMQWSQVSSSLLESLETDRVKFPEIYEARATRYRSEPYRLKLSYILEKLRLTQERNNLLADSGWKFDLEGETDNKNLDKVESLYYKSVKEFTYDLELIKNSLISTDLNCESVNTLLTQVHIFGFSLASLDIRQESTRHSDAIQELTNYLDLSVQYDQMSEEEKIKWLIDELNTKRPLIPSDVHWTKTTEETFSVFKMVKRLQQEFGSRICHSYVISMSHSASDLLEVLLLAKEMGLLDQNSQKSKLLVVPLFETVEDLKRAPEVMEKLFKLDFYRSLLPKVGESFKPLQELMLGYSDSNKDSGFVSSNWEIHRAQIALQNLSSRNNILLRLFHGRGGSVGRGGGPAYQAILAQPSGTLKGRIKITEQGEVLASKYSLPELALYNLETVTTAVIQNSLVNNRLDATPEWNQLMSRLAETSRSHYRKLVHENPDLLNFFQEVTPIEEISKLQISSRPARRKKGAKDLSSLRAIPWVFGWTQSRFLLPSWFGVGTALSSELNLDPQQIELLRVLHQRWPFFRMLISKVEMTLSKVDLEVARYYVDTLGSKENKDSFDNIFEVISKEYNLTKSLILEITGKNKLLESDRDLKSSVSLRNKTIIPLGFLQVSLLRRLRDQTRQPPISEFFLDKDESTRAYSRSELLRGALLTINGIAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: VPP3_CAEEL
Sequence: MGSIYRSEHMKLCQIFFQSESAYQCVAELGELGMAQFIDLNEEQNAYTRKFVNEVRRCDEMERKINFVEDEITKDLVPIPDYDEHIPAPQPKHMGEMEANLEKLEEELVQINKNCKVLKNNHVQLLEMKAVLEHVTSLLDPHSKREAAMSISEAARGEAGPISFGMKDEFDKPVKDEKELKFVTGVVKRSKAIAFERFLWRLSRAKVFAKFIQIQEQTELFSNEFEDKCVFILFFSGEQLRAKVKKICDGFQAKCYTVPENPAERTKLLLNIKVQTTDMKAVIEKTLDYRSKCIHAAATNLRKWGIMLLKLKSIFHTLNMFSVDVTQKCLIAECWVPEADIGQVKNSLHMGTIHSGSTVPAILNEMETDKYPPTYFKLNKFTQGFQNIVDAYGIANYREVNPAPWTIISFPFLFAVMFGDAGHGIIMLIAASAFVIFEKKLISMKIKDEIFNTFFGGRYVVLLMGMFAIYTGFIYNDFYSKSVNIFGSSWVNPYNQTLLANMDAQGADSNTDLSLTFPPEIAFNHDYGPYPFGVDPVWNLAINRLNFLNPMKMKTSILLGISQMAFGIMLSLMNHIGNRSVVDIVFVFIPQCLFLGCIFVYLCLQVLMKWIFFYVKPAYIFGRLYPGSNCAPSLLIGLINMFMVKSRDASFAHDVGTAAGKEWVIVNGQNVTYTINDQCYLQQWYPNQSLVELILLLIAVVSVPVMLLVKPFYIRWRHSRGLHIDLGHGPDEHGEFNFGDIMVHQAIHTIEFVLGCVSHTASYLRLWALSLAHAQLSDVLWTMVLRMSLTMGGWGGSAAITILFYFIFSILSVCILILMEGLSAFLHAIRLHWVEFQSKFYGGTGIQFEPFCFTKIIRVYEGLDQ
What is the function of this protein?
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (PubMed:19741196).  In the intestine, required for the rhythmic defecation behavior by promoting acidification in the gut lumen following defecation (PubMed:19741196).  Also, luminal acidification is required for nutrient uptake (PubMed:19741196).
What are the official names of this protein?
V-type proton ATPase 116 kDa subunit a 3, V-ATPase 116 kDa isoform a 3.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase 116 kDa subunit family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Note=Localizes to the apical surface of intestinal cells (PubMed:11441002). Localizes to dot-like structures, possibly P granules, in P2 cells of 4-cell stage embryos (PubMed:11441002).
Protein: PCKG_STRAW
Sequence: MARDIAAPSSVPTQHKELISWVNEIAELTQPDSVVWCDGSEAEYERLSEELVRKGTFRKLDPIKRPNSYYAASDPTDVARVEDRTFICSEKEEDAGPTNHWKDPAEMREIFAGEQGVFRGSMRGRTMYVVPFCMGPLGSDLSAIGVEITDSAYVAVSMRTMTRMGQPVLDELGTDGFFVRAVHTLGAPLEAGEADVPWPCNSTKYISHFPESREIWSYGSGYGGNALLGKKCYALRIASVMARDEGWLAEHMLILKLTPPQGESKYVAAAFPSACGKTNLAMLEPTVGGWTVETIGDDIAWMRFGEDGRLYAINPEAGFFGVAPGTGEHTNANAMKTLWGNSVFTNVALTDDNDIWWEGMTEETPAHLTDWKGNDWTPESGTPAAHPNARFTVPASQCPIIAPEWEDPKGVPISAILFGGRRATAVPLVTESFDWNHGVFLGANVASEKTAAAEGKVGELRRDPFAMLPFCGYNMGDYMGHWVDVAKDKDQAKLPKIYYVNWFRKNDEGKFVWPGFGENSRVLKWIVERLEGRAEGVETPIGILPTREALDTAGLDLSASDLDFLLTVDKEVWREEAALVPEHLNTFGEHTPKELWDEYRALVQRLG
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADA_RIPO1
Sequence: MFTTVRPQSTLTPPTANLIPNDLFTAINELKKDLNAVILAHYYQDPDIQDIADFIGDSLALSQQAASTNAEVIVFAGVHFMAETAKILNPDKLVLLPDLNAGCSLADSCPPEAFAQFKAQYPGCLVVSYINCTAEIKAMSDIICTSSNAVKIVNQLPKDRPIIFAPDRNLGRYVMEQTRRELILWQGSCMVHETFSEKKIVQLKIEYPEAEIIAHPECEPSVLRHANYIGSTTALLNYSQQSASQIFIVATEPGIIHQMEKETPHKRFIPAPAINNCACNECPHMRLNTLEKLYLAMKFKQPEITMDETIRLAALRPIQRMLEMS
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_SALTY
Sequence: MAILGLGTDIVEIARIEAVISRSGERLARRVLSDNEWAIWETHQQPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVFNDELGKPRLRLWGEALTLAEKLGVAHMHVTLADERHYACATVILES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.