PharMolix/UniProtQA huggingface dataset:
Protein: RLMKL_SALG2
Sequence: MNSLFASTARGLEELLKTELEKLGAVGCQVVQGGVHFQGDTRLIYQSLMWSRLASRIILPMGECKVYSDLDLYLGVQAINWTEIFNPGATFAVHFSGLNDTIRNSQYGAMKVKDAIVDAFTRKNLPRPNVDRESPDLRINVWLNKETASIALDLSGDGLHLRGYRDRTGLAPIKETLAAAIVMRSGWQPGTPLLDPMCGSGTLLIEAAMWATDRAPGLHRGHWGFSGWAQHDETIWQEVKAEAQTRARKGLAEYSSHFYGSDSDARVIERARSNARRAGIGELITFEVKDVAQLSNPLPKGPYGTVISNPPYGERLDSEPALIALHSLLGRTMKNQFGGWNLSLFSASPDLLGSLQLRADKQFKAKNGPLDCVQKNYHIAETTADSKPATVAEDYANRLRKNLKKLEKWARQEGIECYRLYDADLPEYNVAVDRYGDWAVIQEYAPPKTVDAQKARQRLFDIIAATLSVLGIPPNKLVLKTRERQKGKNQYQKMSEKGEFLDVSEYNARLWVNLTDYLDTGLFLDHRIARRMLGEMSKGKDFLNLFSYTGSASVHAGLGGARSTTTVDMSRTYLEWAERNLRLNGLSGRAHRLIQADCLGWLREANEQFDLIFIDPPTFSNSKRMEESFDVQRDHVALMKDLKRLLRKGGTIMFSNNKRGFRMDLEGLAELGLTAQEITQKTLSPDFARNRQIHNCWLIRAA
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS1_RICFE
Sequence: MSIKLKQRFVPQLAAINHEFEEDFSKMLETVDTSHIKEKTVVKGQVIEIKNDMVIVDVGLKNEGRIPKSEFLALPEVGDVVEVFIEKIEGRNGRTILSREKAVKEELWGQLEIMCSKGEFVDGTIFGRVKGGFTVDLSGVVAFLPGSQVDVRPIKDPTSIMNIKQPFKILSMDKKLDNIVVSRRAILEESRSEARDEMLSKIKEGMVLEGTVKNITDYGAFIDLGSVDGLLHLTDISWGRVNHPSEVLEFNQKVKVMVIKFDEKTKRISLGIKQLDSNPWEAIKEEFPVGKKMTGKVTNFADYGVFIELRDGLEGLVHSSEISWLKSNQNPRKTLTIGQEVEFVVLEVDTEKHRVSLSIKQCQENPLIKFAENNPVGTIIKAPIRNITDFGIFVALGNNMDGMIHEGDISWEDKGTDLLKSYKKGDEIECKVLAINIEKEQVSLGVKQLSPNPYQEISDEYKKGTIVKALITEVKDDGLEVLLNNKVAGFIKRTELSDEKDEQKPEMFKIDEEIEAKVVSIEKSTGRILLSVKAHKIAERQKALKEYGSSDNTTNMGDILANALEDKK
What is the function of this protein?
Binds mRNA; thus facilitating recognition of the initiation point.  It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity).
What are the official names of this protein?
30S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS1 family.
Protein: ERA_CAMHC
Sequence: MKSGFVSLIGRTNAGKSSLLNFLVGERLAMVSHKINATRRKINGIAMFGEDQIIFIDTPGLHKSEKIMNKLMIDVAIKSIGDADLVLFLASIHDDTRDYEEFLKIAKRPPHILILTKTDETDDGKIAKKLGEYAKFCKEFCAIIPVNIKKKVYRAEILREIAKLLPEHEYFFDPQIISNTNLRDIYRDFILESVYESVSSEIPYNSDVLIEKITEKEQITKISAKIITDTNSHKQILIGKGGETIKRIGIKSRKRISDFSKVKIHLNLQIFVKKGWKNDENLVKSVFVY
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: CIMA_METJA
Sequence: MMVRIFDTTLRDGEQTPGVSLTPNDKLEIAKKLDELGVDVIEAGSAITSKGEREGIKLITKEGLNAEICSFVRALPVDIDAALECDVDSVHLVVPTSPIHMKYKLRKTEDEVLETALKAVEYAKEHGLIVELSAEDATRSDVNFLIKLFNEGEKVGADRVCVCDTVGVLTPQKSQELFKKITENVNLPVSVHCHNDFGMATANTCSAVLGGAVQCHVTVNGIGERAGNASLEEVVAALKILYGYDTKIKMEKLYEVSRIVSRLMKLPVPPNKAIVGDNAFAHEAGIHVDGLIKNTETYEPIKPEMVGNRRRIILGKHSGRKALKYKLDLMGINVSDEQLNKIYERVKEFGDLGKYISDADLLAIVREVTGKLVEEKIKLDELTVVSGNKITPIASVKLHYKGEDITLIETAYGVGPVDAAINAVRKAISGVADIKLVEYRVEAIGGGTDALIEVVVKLRKGTEIVEVRKSDADIIRASVDAVMEGINMLLN
What is the function of this protein?
Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate.
What are the official names of this protein?
(R)-citramalate synthase CimA.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Protein: PYRG_HAEIN
Sequence: MATNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPTQHGEVFVTQDGAETDLDLGHYERFIRTKMTKRNNFTTGKIYSEVLRKERRGDYLGATIQVIPHITNEIKDRVIAGAQGHDVVIVEVGGTVGDIESLPFLEALRQLAVQVGREHTLFMHLTLVPYIPTAGEVKTKPTQHSVKELLSIGIQPDVLICRSDRMIPPNERAKIALFCNVAERAVISLKDVNSIYQIPALLKSQGLDDFVCERFRLTCPEADLTEWEQVLYKQANPVGEVTIGMVGKYTELPDAYKSVNEALKHAGLTNRLSVNIKYIDSQDVETKGVEVLKGIDGILVPGGFGYRGVEGKIRTAQYARENKIPYLGICLGMQIALIEYARNVAGLTKANSSEFDKDCEQPVVALITEWQDAEGNTEVRTDESDLGGTMRLGAQQCHLVSGSRARELYGKETIEERHRHRYEVNNTLLPQIEKAGLKVTGLSADKKLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAAYENHKKSVK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RS2_XANAC
Sequence: MPQVTMRQMLEAGVHFGHQTRYWNPKMAPYIFGARGKIHIINLEKTVPLFNDAMNFLSSVAQKRGTVLFLGTKRSARESIKEEAERCNMPFMTQRWLGGTLTNFRTVKQSVARLKELEAAETDGTFDKLVKHEVLGLRREREKLDASLGGIKEMNRLPDAIFVIDIGHEDIAIKEAKKLGIPVIAVVDTNYDPALVDYAIPGNDDAIRAVQLYARAAADAVLEGKAAAPNSASVREEEFSADAADEGKGRRAPAKKGDKKADAAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: QWRF7_ARATH
Sequence: MATTGRRLRPPSPNNNRSRTISSSISLPVSLNASLSSSTSSSSSSSPSNSSKRVMITRSQSTTRSSRPIGSSDSKSGENIIPARNSASRSQEINNGRSRESFARYLEQRTRGSPRSNASSRGVKPGASSPSAWALSPGRLSTMKTPLSSSAPTTSMCMTPPESPVSKAKIRSGGGGAVAGVLKYFMAQKKVSPVQEEDYHRFRIFQNRLLQWRFVNARTEATMANLKINVEDQLFWVWLRIYKMRNYVVENLIEIQRLRQDIKVREVLSLQMPLLNEWSKIDAKNSEALSKLTRKLHALSVRLPLVHGATIDMVSIHEEMVIAIEVMDEIEDVIIKFLPRVEIILYELTELIGMFNQELLYFEEMDESLLSIPLFTAKESSLRVHILQKTEEQR
What are the official names of this protein?
QWRF motif-containing protein 7.
What is the protein family that this protein belongs to?
Belongs to the QWRF family.
Protein: PYRG_THEMA
Sequence: MKKYVIVTGGVLSGIGKGIFSASLARLMKEHGVDVNVLKIDPYLNVDAGTMNPNQHGEVFVTEDGYEADLDLGHYERFLGRDMTRQNNMTAGQVYLRVIEKERQGKYLGNTVQIVPHLTEEIKDRIRALEAELLVVEIGGTVGDIEGEVFLEAVRELQMEEGKENFLFAHVTYVPYLRTTNEFKTKPTQQSVQLLRRIGITPDMVIVRSEFPLDVPSMNKVALFSGVPRDFVINLPDTKNVYEVPEILRDMGLHEKIASKLNVELKKSTFNWSYPKAFKPYRIALVGKYLGTDDAYKSIIESVFLTGIEKPTVVDSQMLEDMNDEEVKKVLDEYDALIIPGGFGRRGVEGKIKAIKYARENKKPILGICLGMQLMVIEFARNVFGYKEANSTEFDPNTPYPVVDLMEEQKRILKLGGTMRLGAQKVKIFPKTKLYEVYGGVEEVYERHRHRYEANEEAFPELFKKPGEEGYKLVVSAKSDFIEAVELEDHPFFVGVQFHPEYKSKVGAPHPIFVYLRKVLEGSQ
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: ESMA_DROME
Sequence: MCQQVVVVANTNNKMKTSYSIKQVLKTLFKKQQKQQQKPQGSLESLESVDNLRNAQVEEAYYAEIDENAANEKLAQLAHSQEFEIVEEQEDEEDVYVPVRFARTTAGTFFWTTNLQPVASVEPAMCYSMQFQDRWAQA
What is the function of this protein?
Part of the Notch signaling pathway.
What are the official names of this protein?
Enhancer of split malpha protein, E(spl)malpha.
What is the protein family that this protein belongs to?
Belongs to the M4-like protein family.
Protein: HIS2_CORDI
Sequence: MKNFDSLYHELAERAEKRPEGSGTVAALNSSLHTLGKKVIEEAGEVWLAAEYQSDAELAEEISQLMYWAQVIMIKRGLTPEDIYKYL
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_NITEC
Sequence: MTVQFAADKTNIPGRQLFRKWVGAALNKPAEIVIRIVGMQEGEVLNRKFRGKDSATNVLTFVYSDDVPLLGDIVLCAPVISREAEQQNKDLVAHYAHLIVHGVLHLQGYDHISDEDAVVMESLETKIITRLNYPDPYVIQQ
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCST_SYNP2
Sequence: MTLQRTPLHDLAIAAGAKFVPFSGWEMAVQYKGLKVEHQAVRTEVGMFDISHMGKFQLAGENLIAAMQKLVPSNLARLAPGQAQYTVLLNDHGGIIDDVIYYHQGDRQGFLIVNAATTQKDWDWLTHHLTAQGITLTDVSQENILLAIQGPQAEKALQPVVENLDLATLKLFNHGQGQIFGETAFIARTGYTGEDGFEVMVAPTAGKKLWSALIDAGVMPCGLGARDTLRLEAGLHLYGQDMDDDTTPLEAGLGWLIHWQEKDAFIAKDILQTQKAAGVQRRLVGLEMQGRGIARHDYSVLVNGEAVGLVTSGTMSPTLEKAIALAYLPLEFSKVGQAVTVEIRGKQYPAQVVKKPFYRASKK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: SPD12_HUMAN
Sequence: MGQILGKIMMSHQPQPQEEQSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLRELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS
What are the official names of this protein?
Speedy protein E12.
What is the protein family that this protein belongs to?
Belongs to the Speedy/Ringo family.
Protein: KDAD_SACS2
Sequence: MHFIMMKLFRVVKRGYYISYAILDNSTIIRLDEDPIKALMRYSENKEVLGDRVTGIDYQSLLKSFQINDIRITKPIDPPEVWGSGISYEMARERYSEENVAKILGKTIYEKVYDAVRPEIFFKATPNRCVGHGEAIAVRSDSEWTLPEPELAVVLDSNGKILGYTIMDDVSARDLEAENPLYLPQSKIYAGCCAFGPVIVTSDEIKNPYSLDITLKIVREGRVFFEGSVNTNKMRRKIEEQIQYLIRDNPIPDGTILTTGTAIVPGRDKGLKDEDIVEITISNIGTLITPVKKRRKIT
What is the function of this protein?
Participates in a pentose oxidation pathway that converts D-arabinonate to 2-oxoglutarate.
What are the official names of this protein?
2-dehydro-3-deoxy-D-arabinonate dehydratase, 2-keto-3-deoxy-D-arabinonate dehydratase, KdaD.
What is the protein family that this protein belongs to?
Belongs to the FAH family.
Protein: IF6_CANAL
Sequence: MATRTQFENSNEVGVFSNLTNSYCLVAVGGSENFYSAFEAELGDVIPIVHTTIAGTRIVGRMTSGNRRGLLVPTQTTDQELMHLRNSLPDSIKIQRVEERLSALGNVICCNDYVALVHPDIERETEELIADVLGVEVFRQTIAGNVLVGSYCSLSNQGGLVHPQTSIQDQEELSSLLQVPLVAGTVNRGSSVVGAGMVVNDWLSVAGLDTTAPELSVIESIFRLQDAQPDAIGGNLRDTLIETYS
What is the function of this protein?
Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm.  Is also involved in ribosome biogenesis.  Associates with pre-60S subunits in the nucleus and is involved in its nuclear export.
What are the official names of this protein?
Eukaryotic translation initiation factor 6, eIF-6.
What is the protein family that this protein belongs to?
Belongs to the eIF-6 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Note=Shuttles between cytoplasm and nucleus/nucleolus.
Protein: PURO_HALWD
Sequence: MYLGRFIIIGETTAVYRVSSRSYPNRQIISRDNMLTVVPTSEAAQTNNPYVSYNCMRQGGEKIVIGNGSHVDPIAEKIDRGYPARDALAEALLALDYEKDDYNTPRIAGIVGSSSYVGIIRQDAVIIRSISEPTLVSTYENDAPTTAQLSLKGDIEEIAQKAYELEYEHPVCAAAVTHQGQGESGDIVAQIYNGK
What is the function of this protein?
Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.
What are the official names of this protein?
IMP cyclohydrolase, IMP synthase, Inosinicase.
What is the protein family that this protein belongs to?
Belongs to the archaeal IMP cyclohydrolase family.
Protein: RHOX5_MUSMI
Sequence: MEAQSSSRQVTGPLYLGVKEDWEEQHDVKAEAFLQAGEGRKEKGAQGQPGVGAVGKEGEGEELSGGEGQFGPGAPGPMGDEDKDGGTRAGGVEEEQNEPAAEGTESQKNGKPEDRQMPLQGSRFAQQRLSELQSILQRTNSFDVPREDLYRLMDTCVARVQNWFKIRRAAARRNRRRTTPVPEHFRGTFECPACRGVRWGERCPFATPRF
What is the function of this protein?
Transcription factor required for differentiation of embryonic stem cells (ESCs) into primordial germ cells.
What are the official names of this protein?
Homeobox protein Rhox5, Homeobox protein Pem, Placenta and embryonic expression protein, Reproductive homeobox on chromosome X 5.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y427_UREPA
Sequence: MVKSQKVIDVLNTHYNLNLELGSIYAQYAHIADDQFSMPFLAKFIADLSNDKLGVHKNLISEYARKVEIPLHTKFSVDVNFKPANPKELIKHILDTELKVRKHVANMAKVCLEENDFETFSFVKWFVDDGIKDFDDVRTIHDFFENATNNLQVEYAIRKYLKQMKVEEEK
What are the official names of this protein?
Uncharacterized protein UU427.
Protein: MPV17_BOVIN
Sequence: MALWRAYQRALTAHPWKVQVLTAGSLMGLGDVISQQLVERRGLQAHQAGRTLTMASLGCGFVGPVVGGWYRVLDRLIPGTTKVDALKKMLLDQGGFAPCFLGCFLPLVGTLNGLSAQDNWAKLQRDFPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVIWNSYLSWKAHRL
What is the function of this protein?
Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress, and is involved in mitochondrial homeostasis.  Involved in mitochondrial deoxynucleoside triphosphates (dNTP) pool homeostasis and mitochondrial DNA (mtDNA) maintenance (By similarity).  May be involved in the regulation of reactive oxygen species metabolism and the control of oxidative phosphorylation (By similarity).
What are the official names of this protein?
Protein Mpv17.
What is the protein family that this protein belongs to?
Belongs to the peroxisomal membrane protein PXMP2/4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL23_NITMU
Sequence: MSGQTFNPERLMQVILSPQISEKATFIGEKHNQIIFRVAPDATKPEVKAAVELIWKNQKVEVESVRISNVKGKEKRFGRFMGRRGGWKKAYISIKAGQEINFSEISQGEVK
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: BN3D2_DROME
Sequence: MDLENNNNTPLTGKQAEKCAKKRKCVITLDEKQVESKRLKKEESNVEATSRPPAQSPKKRLHLNGKPMQNKDLNFKYGNYKHYYGKRILNKDFHDIRLDVLGTQPDLFRNKQLLDIGCNSGHLSIQIARKFEVKSLVGLDIDRGLINDAQKTVSHLKRHATPGQGIPHIQFVHGNYVLEDDVLLEIERPQFDVILCLSVTKWIHLNFCDSGLKQAFRRMYLQLRPGGKLILEPQSFDGYKRRKKLSEQIRDNYNAIKFRPDHFTEYLLSPEVGFAEMKLMGIPEHCKVGFKRPIQIFTKS
What is the function of this protein?
Probable RNA methyltransferase.
What are the official names of this protein?
Probable RNA methyltransferase CG1239.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: MOMPS_CHLMR
Sequence: MKKLLKSVLAFAVLGSASSLHALPVGNPAEPSLMIDGILWEGFGGDPCDPCTTWCDAISLRLGYYGDFVFDRVLKTDVNKQFEMGPVPTTTDTDAAADITTSTPRENPAYGKHMQDAEMFTNAAYMALNIWDRFDVFCTLGATSGYLKGNSASFNLVGLFGDGVANAANAIATVAADSLPNVSLSQAVVELYTDTAFAWSVGARAALWECGCATLGASFQYAQSKPKVEELNVLCNAAQFTINKPKGYVGKEFPLALTAGTDSATDTKDASIDYHEWQASLALSYRLNMFTPYIGVKWSRASFDADTIRIAQPKLAEAILDVTTWNPTIAGAGTIADGTGAAATANGLADTLQIVSLQLNKMKSRKSCGLAIGTTIVDADKYAVTVETRLIDERAAHVNAQFRF
What is the function of this protein?
Permits diffusion of specific solutes through the outer membrane.
What are the official names of this protein?
Major outer membrane porin, MOMP.
What is the protein family that this protein belongs to?
Belongs to the chlamydial porin (CP) (TC 1.B.2) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: NAT8L_DANRE
Sequence: MHCSSPKMVCETKIVADEHEAIAGTKKDSIIVSSSQMWTSSSASPSALESKIEKRNQVFIREFERSDHEEVRRIFNEGIMERIPNSAFRGLKQQTTTQFMYAFLTVMCYVMTKSFTLTFCAPFILMGARYYYSRKVILSYLDCALHTDMADIEAYYMKPTGSCFWVAVLQGQVVGIVAAQSREDDNTVELRRMSVDSHFRGKGIAKALGRRVIEFAMLNNYSAVVLGTTAVKMAAHKLYESLGFRRVGETEDYTLPGMTRSPLERLFFQIRYSHYRLQLHEE
What is the function of this protein?
Catalyzes the synthesis of N-acetylaspartate acid (NAA) from L-aspartate and acetyl-CoA.
What are the official names of this protein?
N-acetylaspartate synthetase, NAA synthetase, N-acetyltransferase 8-like protein.
What is the protein family that this protein belongs to?
Belongs to the camello family.
What are the subcellular locations of this protein?
Cytoplasm. Microsome membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: NUOH_RUEPO
Sequence: MAEFFDTPGGIALIILAQVLAVVAFVMISLLFLVYGDRKIWAAVQMRRGPNVVGVYGLLQSVADALKYVVKEVVIPAGADRTVFILAPMTSFVLAMIAWAVIPFNDGWVLSDINVAILYVFAVSSLEVYGVIMGGWASNSKYPFLGSLRSAAQMISYEVSIGLIIIGVILSTGSMNFGDIVRAQDTGWGFFGWYWLPHFPMVFLFFISALAETNRPPFDLPEAESELVAGYQVEYSATPFLLFMAGEYIAIFLMCALTSLLFFGGWLSPIPGLPDGVLWMVAKMAFFFFIFAMVKAITPRYRYDQLMRLGWKVFLPFSLVWVVFVAFAAKFDWFWGAFARWSVGG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FPG_YERPN
Sequence: MPELPEVETSRRGIEPYLVGQTILYAVVRNARLRWPVSDEILTLSDQPVLSVQRRAKYLLLELPKGWIIIHLGMSGSLRVLSEETAAEKHDHVDLVVSNGKILRYTDPRRFGAWLWAKDLETSNVLAHLGPEPLSDEFTAQYLFDKSRNKRTLIKPWLMDNKVVVGVGNIYASESLFAAGILPDRAAGSLTDAESVLLVATIKAVLLHSIEQGGTTLRDFLQSDGKPGYFAQELQVYGRAGEPCRQCGHPIEIAKHGQRSTFFCRHCQH
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: FETP_BORA1
Sequence: MARTVNCVKLKREAEGLDYPPYPGELGARIWREISKESWEEWKQIQTRLVNENRLNLADARARKYLQQQMERFLFEDGTVEAQGYVPPSA
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: EREB_ECOLX
Sequence: MRFEEWVKDKHIPFKLNHPDDNYDDFKPLRKIIGDTRVVALGENSHFIKEFFLLRHTLLRFFIEDLGFTTFAFEFGFAEGQIINNWIHGQGTDDEIGRFLKHFYYPEELKTTFLWLREYNKAAKEKITFLGIDIPRNGGSYLPNMEIVHDFFRTADKEALHIIDDAFNIAKKIDYFSTSQAALNLHELTDSEKCRLTSQLARVKVRLEAMAPIHIEKYGIDKYETILHYANGMIYLDYNIQAMSGFISGGGMQGDMGAKDKYMADSVLWHLKNPQSEQKVIVVAHNAHIQKTPILYDGFLSCLPMGQRLKNAIGDDYMSLGITSYSGHTAALYPEVDTKYGFRVDNFQLQEPNEGSVEKAISGCGVTNSFVFFRNIPEDLQSIPNMIRFDSIYMKAELEKAFDGIFQIEKSSVSEVVYE
What is the function of this protein?
This enzyme confers resistance to erythromycin through inactivation by hydrolyzing the lactone ring of the antibiotic.
What are the official names of this protein?
Erythromycin esterase type II.
Protein: UBL3_BOVIN
Sequence: MSSNVPADMINLRLILVSGKTKEFLFSPNDSASDIAKHVYDNWPMDWEEEQVSSPNILRLIYQGRFLHGNVTLGALKLPFGKTTVMHLVARETLPEPNSQGQRNREKTGESNCCVIL
What are the official names of this protein?
Ubiquitin-like protein 3, Membrane-anchored ubiquitin-fold protein, MUB.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: Y4007_BACC1
Sequence: MTLQTFKSTDFEVFTVDGLEERMSAIKTNIHPKLEALGEQFAAYLSKQTDENFFYHVAKHARRKVNPPNDTWVAFSTNKRGYKMLPHFQIGLWGTHAFIYFGLIYECPQKVETAHAFLEHINDLKTNIPNDFVWSIDHTKPSVKLHKTLETNDLQKMIERLATVKKAELLVGIHISPEEFSAMTNEQFLAKIESTMQSLLPLYALCNR
What are the official names of this protein?
UPF0637 protein BCE_4007.
What is the protein family that this protein belongs to?
Belongs to the UPF0637 family.
Protein: TX2M1_LYCSI
Sequence: MIKYVLISALLVVAVYSFTIEDNEDALLEEAEDELDTEEERRMALPPGAVCNGHKSDCQCFGAKYKCSCPLLWRFRRSAKCHCKKGWAWTAIKKRSCHNRYQWSG
What is the function of this protein?
Insecticidal to house crickets.  It induces an excitatory slow-onset impact that leads to irreversible spastic paralysis.  It also modifies human voltage-gated potassium channel Kv1. 5/KCNA5.  Most likely, it binds to the voltage-sensing domain of the channel, suggesting it does not block the pore but prevents its opening at physiological membrane potentials.  The recombinant peptide binds to the channel in an irreversible manner and slows down the hKv1. 5 current activation kinetics.  It is not toxic to mice, when intracranially injected (at 0. 5 ug/g mouse).
What are the official names of this protein?
U2-lycotoxin-Ls1a, U2-LCTX-Ls1a, Toxin LSTX-M1.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 04 (omega-agtx) family. 01 (type I omega-agtx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HSPB8_RAT
Sequence: MADGQLPFPCSYPSRLRRDPFRDSPLSSRLLDDGFGMDPFPDDLTAPWPEWALPRLSSAWPGTLRSGMVPRGPTATARFGVPAEGRNPPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVEVSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPPYSPFGESSFNNELPQDNQEVTCS
What is the function of this protein?
Displays temperature-dependent chaperone activity.
What are the official names of this protein?
Heat shock protein beta-8, HspB8, Alpha-crystallin C chain, Small stress protein-like protein HSP22.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to nuclear foci during heat shock.
Protein: AROC_METAC
Sequence: MAGNIFGQMFRIATWGESHGRAVGVVVDGLPAGLPFSEADIQKELDRRRPGQSEVSTPRSEADRVEILSGIFEGMSTGTPISMLVWNSDARSSSYDVIKNTPRPGHADFSYMARYGIRDHRGGGRSSARETIGRVAGGALAKLLLSRYGVRIAGHVLELGGIRAKPLSFEEILENVEKTPVRCADLEAAEKMLEKVATLRQEGDSVGGIVELIVKGVPAGLGEPVFDRLDADLSKALMSIPAVKGFEIGAGFEAARMRGSEMNDPFRMEQGEITCSKNNAGGILGGISTGLDIICRAAVKPTPSIGKVQQTVDLTTRENTEISIRGRHDPTIPPRMVPVAEAMVALVLSDHMLRSGFINPRTLLE
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RL5_BURP6
Sequence: MARFQEFYKEKVVPGLIEKFGYKSVMEVPRITKITLNMGLGEAVADKKIIENAVGDLTKIAGQKPVVTKARKAIAGFKIRQGYPIGAMVTLRGRAMYEFLDRFVTVALPRVRDFRGVSGRAFDGRGNYNIGVKEQIIFPEIDYDKIDALRGLNISITTTAKTDDEAKALLASFKFPFRN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.