PharMolix/UniProtQA huggingface dataset:
Protein: Y424_MYCPN
Sequence: MNQTKLNQRLKQQQLFDIYGELLTKRQACYFNEYINLDLSMQEIADKYQVKKSSIHQHIKTCNLIFNRFEAKLQLFKKQQLRLKLYEKITDPQLREQLIKLR
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein (By similarity).
What are the official names of this protein?
UPF0122 protein MPN_424.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: Y873_TREPA
Sequence: MDITINGHTLQYVIEHEKTIGEVLGAIEAACKKEKQTVSAVTVNGRELSANELDTLFCQSLDTDVTLNLTTLSGGDVRALLREISTTLLARTAALQEIAVNMHSGNLAESYAMVSDFSALLKSLYHCFTLSDIADLDHGLRIKGKALHDYQREISPLLKGLLEAMEEGDSVAVGDIAEYELAPVVRDLSDGILHMDMGVQ
What are the official names of this protein?
Uncharacterized protein TP_0873.
Protein: RL18E_SULTO
Sequence: MVARTGSTNIMVRKLIDLLSKQKKPLWKRVAEELQKPSRQRPYINIYKINKYTKPNDVVVVPGKVLGIGNLDHPVTVVALSFSKSAKEKIEKSGGKVISLYKALEEVKDFKNVRLMKG
What are the official names of this protein?
50S ribosomal protein L18e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL18 family.
Protein: HEM1_CHLSY
Sequence: MNLFLAGLDHTTAPVEIREQLAFSQTDLPSALMQLTSSETGTPPLFAEAVILSTCNRVELYGVTNPGTTAQHVVDFLAAFHRRPAASFVHTLYFYQGEAVARHLCATAAGLRSLVLGEAQIQGQVRNAYEAAQRIGSVGSILHRLFQIALVAGKRVRHETTIGKGAASVSQAGVELARRRLGDLRGREVLLIGGGEVSELAAQNLIANGADRLTIVNRTSARAAALAERYGAEMLDFGALPQALARADIVISSTAAPVPIIYRHHVAEAIAHKQRARACGECDPPTMLLIDLAVPRDIAADVAQIPGVHLFTVDDLREVVSHTIELRSAVLEIAQQIVEEQVQEFLSWMRTQEALPVLTMLRQRAEEVRNEELARALRRLHDLSPEQRAVIEGLSRSIVNKLLHPPTRCLREAAAHGQGKRYASILAELFNLEH
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: QUEA_RHIEC
Sequence: MRVDLFDFDLPDERIALRPAEPRDSARLLVVDPDAESALSDHHVCDLPSFLRAGDALVFNDTKVIPAQLEGIRHRDGAGGQQVSATLHMRIGPSRWKAFAKPGKRIKEGDRIAFGHSGESCMIGSLDATVEEKGEAGEVTLAFDLSGPVLDEAIAAVGHIPLPPYIAAKRPEDERDRADYQTIYAREEGAVAAPTAGLHFTPALFEALDKAGIERHFVTLHVGAGTFLPVKADDTDDHKMHLESGYVSGEIAAGLNAVKARGGRIVCVGTTSLRLIESAAGESGEIKPWAGATGIFITPGYRFKAVDMLMTNFHLPRSTLFMLVSAFSGFETMHAAYKHAISTGYRFYSYGDASLLFRKDK
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_POLNS
Sequence: MIIGIGTDILQIERLQAAYDRTKGRLAEKILGPDEMLVFQHRLARNHKRGIAFLATRFAAKEAFSKAIGLGMRMPMAWRSLQTLNEPSGRPVTSYLGTLAQFMQEKNWEAHVTVSDEQDMAIAQVIVTQKIRGSDE
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_HISS2
Sequence: MSRVCQVTGKRPAVGNNRSHAMNATRRRFLPNLHTHRFWVESEKRFVTLRLTAKGMRIIDKKGIDAVLAEIRARGEKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: PURR_VIBA3
Sequence: MATIKDVARLAGVSTTTVSHVINKTRFVAEATQEKVNKAVDELNYAPSAVARSLKCNTTRTIGMLVTQSTNLFFSEVIDGVESYCYRQGYTLILCNTGGIYEKQRDYIRMLAEKRVDGILVMCSDLTEELREMLDRHADIPKVIMDWGPESSQADKIIDNSEEGGYLATKYLIERGHSKIACLSGHLDKAACVERISGYKRALNEAKITADENMIIEGNFECDTAVIAADQIIEMEERPTAVFCFNDTMALGLMSRLQEKGIRIPEDISVIGYDNIELAEYFSPPLTTVHQPKRRVGKNAFEILLERIKDKDHEKRVFEMHPEIVERSTVKTLN
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: SUCC_STRGG
Sequence: MDLFEYQARDLFAKHGVPVLAGEVIDTPEAAREATEKLGGKSVVKAQVKVGGRGKAGGVKLAADPDEAVARATDILGMDIKGHTVHKVMIAELSPEIEAEYYVSYLLDRTNRTFLAMASVQGGMDIEEVAEKTPEALAKVPVNAVDGVDIAKAREIVAQAKFPADVAEGVAEALVTLWDTFVAEDALLVEVNPLVKTKDGRILALDGKVSLDENADFRQPDHEALEDKDAANPLEAAAKAKNLNYVKLDGEVGIIGNGAGLVMSTLDVVAYAGENHGNVKPANFLDIGGGASAEVMANGLEIILGDPDVRSVFVNVFGGITACDEVANGIVQALALLESKGEKVEKPLVVRLDGNNAELGRKILSDANHPLVQRVDTMDGAADKAAELAAAAK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: AMPP_PLAF7
Sequence: MQLNFLLFVFIFLMVFHLNIFNKGKRQNLVSAYLNHFKKSYFSGVTSGSDCVNKSEVSSDNNNNNNNNNNKIAHNFFSKKYQRNFENNNLSENQENNKNIIYSGSNIFKNIYNTEMMSNNNTVDVNMMDNNPAARLEELRTIMKKNKIDVYILINSDEHNSEIINEKDKKIVKITNYSGADGILIVTKDKPILYVNALYELQAMNELDQNLFTLRISRIDNRDEIFETISSLEFNTIAFDGKNTSVVFYEKLRKALLNAYPKKKIVEKIIYNNNFDDVNKKDDENVLNFLVLEKSLVEIKDYPVNNKTLYIHDRKYNGACAGEKIDKLKQSLMYDIKNVDNLLLSELDEIAYLLNLRGYDYQYSPLFYSYLLFQFDREEQDFSKIVFFTTVKNLPADVKNLLEINKVIVKEYEEIVPYLRDVVIPSIPKHNDDNPDFKKYDISLSPYINLMIYKLFDRKNVLLQNSPVVKMKAVKNDVEIDNMKQAHILDGLALLQFFHWCEQKRKTKELFNETEMSLRHKVDYFRSTKKNFIFPSFSTISASGPNAAVIHYECTDKTNATIKPAIYLLDSGGQYLHGTTDVTRTTHFGEPTAEEKRIYTLVLKGHLRLRKVIFASYTNSSALDFIARENLFNNFMDYNHGTGHGVGLTLNVHEGGCSIGPVGGAPLKKNMVLSNEPGYYMKDKFGVRIENMQYVISKEITDTTEYLSFDDLTMYPYEKKLLDFSLLTNQEIKELNEYHTTIRNTLLPLVKQSPQEYGESVEKYLIEITEPIAIHNN
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides (PubMed:17895246, PubMed:19574214, PubMed:27462122).  In the food vacuole, involved in the final step of host hemoglobin catabolism, by cleaving hemoglobin-derived oligopeptides (PubMed:17895246, PubMed:19574214).  In the cytoplasm, may be involved in the last steps of the turnover of ubiquitinated proteins (Probable).
What are the official names of this protein?
Aminopeptidase P, PfAPP, Xaa-Pro aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: O16A_CONGL
Sequence: MKLTCMMIVAVLFLTAWTFVTADDSGNGMEILFPKAGHEMENLEVSNRVKPCRKEGQLCDPIFQNCCRGWNCVLFCV
What is the function of this protein?
Delta-conotoxins bind to site 6 of voltage-gated sodium channels (Nav) and inhibit the inactivation process.  This toxin shows weak activity on rNav1. 2/SCN2A (EC(50)=2. 5 uM) and rNav1. 4/SCN4A (EC(50)=4. 8 uM) (PubMed:10627583).  In vivo, injection of this peptide in the head region of garden snail induces retraction of the head and body into shell.  This is followed by secretion of viscous green slime and a convulsive undulation into and out of the shell.  No apparent biological activity was observed when a much greater dose of peptide was injected intraperitoneally into mice.
What are the official names of this protein?
Delta-conotoxin GmVIA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SCAF_SUHVK
Sequence: MGPVYVSGYLALYDRDGGELALTREIVAAALPPAGPLPINIDHRPRCDIGAVLAVVDDDRGPFFLGVVNCPQLGAVLARAVGPDFFGDMRLSDEERLLYLLSNYLPSASLSSRRLAPGEAPDETLFAHVALCVIGRRVGTIVVYDASPEAAVAPFRQLSARARSELLARAAESPDRERVWHMSEEALTRALLSTAVNNMLLRDRWELVAARRREAGVRGHTYLQATMWAGLLPKSGASPAPGPSAAMAAPPSAAPGDYIFVPAAQYNQLVVNQRPAPSLESQLGAIVSAAMDRRHRRSPSPEPRPPARKRRYDDYAQDNAYYPGEAPPPASDLAAVVSSLQREISHLRAQQLRYPTPYYAPAAPPQLLPPGAVVGHPHPHHAAGALYPPMYAPQPGLHAPPPSPVAHAVPALPGLPGLQGLAAPVAHVPAQVVPQQPVVVQAQPVAVPAAAAAAPAPAPAAAAAAAAPVQAAAPAAPASAPQPPVQASVSAPADVSAGTIDASSAAVACQRGADIFVSQMMSQR
What is the function of this protein?
Plays a major role in capsid assembly.  Acts as a scaffold protein by binding major capsid protein.  Multimerizes in the nucleus such as major capsid protein forms the icosahedral T=16 capsid.  Cleaved by assemblin after capsid completion.  The cleavages products are evicted from the capsid before or during DNA packaging.
What are the official names of this protein?
Capsid scaffolding protein, Capsid protein P40, Protease precursor, pPR, Virion structural protein UL26.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae capsid scaffolding protein family.
What are the subcellular locations of this protein?
[Capsid scaffolding protein]: Host cytoplasm. SUBCELLULAR LOCATION: [Assemblin]: Host nucleus. SUBCELLULAR LOCATION: [Assembly protein]: Host nucleus.
Protein: ASB17_CANLF
Sequence: MSKSSKLCRKTSCPRSNIFCNLIDKIVKRPSLQFLGQWGYHCYEPRIYRTLAKILRYVDLDGFDILLSDYIAFVEKSGYRFELNFNLEFTEICVNTILYWVFARKGNPDFVELLLKKTKDYVQDRSCNLALIWRTFTPVYCPSPLSGITPLLYVAQTRQSNILKILLQYGILEREKNPINIVITILLYPSRVRIMVDHELVDIQEDAKTCLVLCSRVLSAISIREIETQLSLGRRPIISNWLDYIPSTRYKDPCELSHLCRITIRAQLLTNNMLPNGIFSLQIPXRLQKYLNLES
What is the function of this protein?
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Ankyrin repeat and SOCS box protein 17, ASB-17.
What is the protein family that this protein belongs to?
Belongs to the ankyrin SOCS box (ASB) family.
Protein: M3K12_MOUSE
Sequence: MACLHETRTPSPSFGGFVSTLSEASMRKLDPDTSDCTPEKDLTPTQCVLRDVVPLGGQGGGGPSPSPGGEPPPEPFANSVLQLHEQDTGGPGGATGSPESRASRVRADEVRLQCQSGSGFLEGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRFHGEEVAVKKVRDLKETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQETYFKSQAEWREEVKLHFEKIKSEGTCLHRLEEELVMRRREELRHALDIREHYERKLERANNLYMELNALMLQLELKERELLRREQALERRCPGLLKSHPSRGLLHGNTMEKLIKKRNVPQKLSPHSKRPDILKTESLLPKLDAALSGVGLPGCPKGPPSPGRSRRGKTRHRKASAKGSCGDLPGLRAALPPHEPGGLGSPGGLGVGPSAWDACPPALRGLHHDLLLRKMSSSSPDLLSAALGARGRGATGGARDPGSPPPPQGDTPPSEGSAPGSTSPDSPGGAKGEPPPPVGPGEGVGLLGTGREGTAGRGGNRAGSQHLTPAALLYRAAVTRSQKRGISSEEEEGEVDSEVELPPSQRWPQGPNMRQSLSTFSSENPSDVEEGTASEPSPSGTPEVGSTNTDERPDERSDDMCSQGSEIPLDLPTSEVVPEREASSLPMQHQDGQGPNPEDSDCDSTELDNSNSIDALRPPASLPP
What is the function of this protein?
Protein kinase which is part of a non-canonical MAPK signaling pathway (PubMed:7983011, PubMed:8663324, PubMed:28111074).  Activated by APOE, enhances the AP-1-mediated transcription of APP, via a MAP kinase signal transduction pathway composed of MAP2K7 and MAPK1/ERK2 and MAPK3/ERK1 (PubMed:28111074).  May be an activator of the JNK/SAPK pathway.
What are the official names of this protein?
Mitogen-activated protein kinase kinase kinase 12, Dual leucine zipper bearing kinase, DLK, Leucine-zipper protein kinase, ZPK, MAPK-upstream kinase, MUK, Mixed lineage kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Behaves essentially as an integral membrane protein.
Protein: Y4376_PSEMY
Sequence: MSIRDWPAAERPREKLLAQGAAALTDAELLAIFLRTGVAGCSAVDLARRLLAEFGSLRALLEAELPDFSQHLGLGPAKYAQLQAVLEMARRHLAERLRRDSALESPQAVRDYLKAQLRHEPHEVFGCLFLDAKHRVLAFEVLFRGSIDSASVYPRQVVKRALANNAAAVILTHNHPSGVCEPSQADRVLTQRLKDALALVEVRVLDHFIVGDGEPLSMAELGWM
What are the official names of this protein?
UPF0758 protein Pmen_4376.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: Y1885_XANOR
Sequence: MIKWAIIFAIIGLIAGALGFGGMAGAAMGIAKFLFWAGIIIAIVLFVLGMTIAKKVI
What are the official names of this protein?
UPF0391 membrane protein XOO1885.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL16_NOSP7
Sequence: MLSPRRTKFRKQQRGRMEGLATRGSTLNFGDFALQAQEPAWITSRQIEASRRAMTRYIRRGGQIWIRIFPDKPVTMRPAETRMGSGKGNPEFWVAVVKPGRILFEIGGVSEEIAREAMRLASFKLPIKTKFIVRSQPQEQE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: COFH_MICAN
Sequence: MTNSSITAPVTDILAKARSGANLSAKEAIILLETTDNRLIAWIRETADFLRRQQTGDTVTYVINRNINFSNICEQHCSFCAFRRDEDEEGAFWLNLEEIIAKAADAVRRGATEICMQGGLNPKAKIKGNSLDYYLEIVKNLKQAFPDLHLHAFSPQEVQFIAREDGLSYEKVIASLQEAGVNSLPGTAAEVLVDEVRRVICPEKIDAATWLEIVGTAHRLGLHTTSTMLCGHIETPSQQVQHLEKIRKQQEIALENNYPAKITEFILLPFVGQSAPKPLRNRVGQDQPILADTLKLTAVARIYLGNSIKNHQPSWVKLGLQGATEALNWGCNDLGGTLMEEHITTMAGALGGTCLTVEELATAIKSLDRPARQRDTIY
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
What are the official names of this protein?
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase, FO synthase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofH family.
Protein: RL23_NEIMF
Sequence: MGMNQQRLTQVILAPIVSEKSNVLAEKRNQMTFKVLANAAKPEIKAAVELLFGVQVASVTTVTTKGKTKRFGRTLGRRSDVKKAYVSLAAGQELDLEAAAAAADKE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RS8_PECCP
Sequence: MSMQDPIADMLTRIRNGQAANKVAVTMPSSKLKVAIANVLKEEGYIEDFKIEGDTKPVLELELKYFQGKAVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVVSTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RS17_STRP6
Sequence: MERNQRKTLYGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKKYKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: CSRA_SALTI
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQAEKSQQSSY
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
Protein: ATPD_TRYBB
Sequence: MFRTFGRRLVSCTLPLLQSAPHDLPEGFEFMEHKVVNKDIHAPHENLEXLRLTLTRQDEFLLREEPVKCVTVTGTNGEYGIYPGHAYKIVQLNPSPLTVEYTDGTTKKYFVSGGFAHINNEGSCDVNTVECTLLDDLDLAIAEKELAAQQAALGSAKDDKAKSVVEIRISVIEAVIAALKHH
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(o) ATP synthase) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:19436713, PubMed:29247468).  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(o) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk (PubMed:19436713, PubMed:29247468, PubMed:29440423).  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Subunits alpha and beta form the catalytic core in F(1) (PubMed:19436713, PubMed:29440423).  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits (Probable).  Contrary to the procyclic, insect form that requires F(1)F(o) ATP synthase for ATP synthesis, the bloodstream form relies on ATP hydrolysis by F(1)F(o) ATP synthase to maintain its mitochondrial membrane potential (PubMed:29247468).
What are the official names of this protein?
ATP synthase subunit delta, mitochondrial, ATP synthase F1 subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: Y3475_RHOJR
Sequence: MTDSPADLRSAFRSGRVTPTAGLAPGFAQTNLIAVPQDWAYDVLLFTQRNPKPCPVLDVGDVGSRETVLAPGADITTDLPLYRVWKDGELADETADVSGLWRDDLVAFHIGCSFTFEHPVAAAGVPLRHVEQGSNVPMFVTNRECRPAGRMSGPMVVSMRPVPEHQVSLAAAISARMPAVHGGPVHIGDPTELGIADVAAPDFGDPVNFEPGDVPVFWACGVTPQAAVMASRLPFAITHAPGYMLITDIPDSEYVLEVPDAR
What are the official names of this protein?
Putative hydro-lyase RHA1_ro03475.
What is the protein family that this protein belongs to?
Belongs to the D-glutamate cyclase family.
Protein: NFUA_YERPP
Sequence: MITITDAAQSHFAKLLANQEEGTQIRVFVINPGTPTAECGVSYCPPDAVEATDTELKFEQLSAYVDELSVPYLQDAEIDFVTDQLGSQLTLKAPNAKMRKVDDSAPLMERVEYVLQSQINPQLAGHGGRVTLMEITPEGLAILQFGGGCNGCSMVDVTLKEGIEKELLQKFPELKGVRDLTEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: CYSD_SHIDS
Sequence: MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFIHGSAKHTDIMKTEGLKQALNKYGFDAAFVGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: HSCB_PSEAE
Sequence: MGKPCHFAQFDLQPAFLVDLDELGQRYRELVRSVHPDRFADAPEREQRLALERAAQLNEAYQTLKSAPRRALYLLTLSGHELPLEATVQDPEFLLQQMQLREELEELQDSADLAGVATFKRRLKAAQAELEREFAACWDDAQRREEAERLVRRMQFLDKLAQEVRQLEERLDD
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: DER_STRPM
Sequence: MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYATGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAQIAMEEADVIVFVVSGKEGVTDADEYVSKILYRTNTPVILAVNKVDNPEMRNDIYDFYSLGLGDPYPVSSVHGIGTGDVLDEIVENLPVEEAEENDDIIRFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFTDADGQEFTMIDTAGMRKSGKIYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHEAGKGMIIVVNKWDTIDKDNHTVAKWEADIRDQFQFLTYAPIIFVSALTKQRLNKLPDLIKRISESQNKRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVSVKPPTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIHLIARKRK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: DNAK_STRPZ
Sequence: MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKNGEIIVGDAAKRQAVTNPETVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAEDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGMDKTDKDEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVEEFKKENGIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGSAGPLHLEMSLSRAKFDDLTRDLVERTKTPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKSVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDKNGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIDRMMKDAEANAEADAKRKEEVDLKNEVDQAIFATEKTIKETEGKGFDTERDAAQSALDELKAAQESGNLDDMKAKLEALNEKAQALAVKMYEQAAAAQQAAQGAEGAQANDSANNDDVVDGEFTEK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.