PharMolix/UniProtQA huggingface dataset:
Protein: PEX5_CANAL
Sequence: MSFVGGGSECSVNGNAVAQFNKHTQQDRSLQQQVANQHGNVAQNQGFKKDNLMNVRDRANLDQFMNNGAPQNSFQFQPMRHELNTIQNQPNAIHQQQSNWSQDFVAQSPSAQITTPIAKTGSPVNAQWASEFSQAPATQQHNQRPGQFGPRLGGYRPMMGMSMAYQSQPQQQQQQQHNQEPQVDWENQFKEIEELTNKAEEVEEIQREQSPEIVVDDKYQATFQEVWDSLNSESFENDFINQQYEDFKRTQKDGFPADMNQWEKDFAKYASTRAHFGDYQFEDKQSNQFLDLPKDQDPYEIGLQLMENGAKLSEAALAFEAAIQRDENHVDAWLKLGEVQTQNEKEIAGISALEKCLELHPENSEALMNLAISYINEGYDNAAFATLERWISTKYPQIVEKARQENPTITDEDRFSLNKRVTELFLNAAQLSPNQASMDADVQMGLGVLFYANEEFDKTIDCFKAALSIRPDDAILWNRLGASLANSNRSEEAVDAYFKALQLKPTFVRARYNLGVSCINIGCYKEAAEHLLSGLSMHQVEGVDTVSTLNHNQSTSLTETLKRAFIAMERRDLLELVKPNMDLNQFRGEFSF
What is the function of this protein?
Receptor that mediates peroxisomal import of proteins containing a C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type).  Binds to cargo proteins containing a PTS1 peroxisomal targeting signal in the cytosol, and translocates them into the peroxisome matrix by passing through the PEX13-PEX14 docking complex along with cargo proteins.  PEX5 receptor is then retrotranslocated into the cytosol, leading to release of bound cargo in the peroxisome matrix, and reset for a subsequent peroxisome import cycle.
What are the official names of this protein?
Peroxisomal targeting signal receptor, PTS1 receptor, PTS1R, Peroxin-5.
What is the protein family that this protein belongs to?
Belongs to the peroxisomal targeting signal receptor family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome membrane; Peripheral membrane protein. Note=Its distribution appears to be dynamic. It is probably a cycling receptor found mainly in the cytoplasm and as well associated to the peroxisomal membrane (By similarity).
Protein: TRUA_ECOLI
Sequence: MSDQQQPPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALSQVANEPITVFCAGRTDAGVHGTGQVVHFETTALRKDAAWTLGVNANLPGDIAVRWVKTVPDDFHARFSATARRYRYIIYNHRLRPAVLSKGVTHFYEPLDAERMHRAAQCLLGENDFTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLMEVGAHNQPESWIAELLAAKDRTLAAATAKAEGLYLVAVDYPDRYDLPKPPMGPLFLAD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, PSU-I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: IF1_TREPA
Sequence: MTKEEAIEVDGVVKEALPNTTFRVQLQNGHEILAYLSGRMRKHYIRIVPGDSVKVALSPYDLSRGRIMFRER
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSOCA_PROMP
Sequence: MPLRGLAKAKNFTLGPTAPMKTFTENVHSQNNEINNLKKIDKTHNLTNNSQNEKLYKYESQIKSSFDRIVPTLKEIARIQHHEDFINTAQSISKQNLGINLPTHILDKSWVKPLDMRALYAWCAFKQHEKLSDNFFENDPLEGSFGSPNANNFETALLDCGIHLLDITPCSDGRLAHSVAYVMRIPFSAVRRRSHAGALFDIENTVNRWVKTEHKRYRENNPNEAHEDTRYLKIVTYHFSSVDPLHQGCAAHGSDDKLAAKEGSEKLLAFKEAVENSFCCGASVDLMLIGLDTDTDSLKIHLSSSDGKIDLENTISSLDIYNSTINFSKDEAEKEICQIISGNSNKVQLKGLDKFVYKLIVNNISQIDYVKKFHKGSYEDIGHAERFIGVGIGFKEVHLRNLTYFAHLDTVEEGAPDLDVGVKIFTGLNVSQDLPIPIVIRFDYSGKVPGAKERAAKDCYRVNNAISIRYKSLVDKGLLHTCLTIRDRDNIHSAQIIGMSLDQKTKEAH
What is the function of this protein?
Reversible hydration of carbon dioxide (PubMed:14729686).  Essential for photosynthetic carbon dioxide fixation, supplies CO(2) to RuBisCO (ribulose bisphosphate carboxylase, cbbL-cbbS) in the carboxysome (Probable).  There are estimated to be 29 CsoSCA oligomers per carboxysome (PubMed:22155772).
What are the official names of this protein?
Carboxysome shell carbonic anhydrase, CsoSCA, Carbonic anhydrase, CA, Carboxysome shell protein CsoS3.
What is the protein family that this protein belongs to?
Belongs to the beta-class carbonic anhydrase family. CsoSCA subfamily.
What are the subcellular locations of this protein?
Carboxysome. Note=While the protein is very difficult to identify due to its low abundance, the enzyme activity fractionates with the carboxysome. This cyanobacterium makes alpha-type carboxysomes.
Protein: TRUB_SYNP6
Sequence: MSSEGFVNLDKPAGWTSHDCVAKLRRLLRERRIGHGGTLDPAVTGVLPIAVGRATRLLPYLPSGKTYVGTIRFGLQTSTDDLTGDRLAEADTSHLSREAIEAALPQFLGHIQQQPPQVSAVQVQGQRLYQLARRGEAPTELPWRTVEIQSIRILQWRSGSQAELSVEIHCGAGTYIRSLARDLGAVLGVGGTLAELRRTASSGFDLNQSTPLTELLDGAAVPLLALDLPLQHLAKVQLSAETSDRWRQGQAMPVPDSVLPDAAPVRVYDLNGQFLGIGAIAAGLCKPKVVLAAL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: STHE_PHANO
Sequence: MLPANGQTAVIQSKTSSHGLPLVVAHGRPLPPLPTPYHVRVRVLAVGLNPTDYKMVTHFFMQDNTAGCDFCGIVEEAGPQSVLGLGLRVCGADFPYRPSNPYNGAFAEYATADSRHLLRIPDGVSDLQAAGIGAIGWGTAALAISDPAALDLPGLPSRPDSRGLPVLVYGGATATGIMAIQMLKLSGYSPIAVCSESSAPLCMSLGAIGTASYTSVTCAEDIKAIAKGSKIKHALDCITDVESMAICLASLSRTGGRYACLEAFPDAWLTRRAIAVKVVMGFEGQNVDVDLGHPVYTRKANPALHAVAGEWARELQLLLNDGQIKTQPMQEIGGSFEGVIKALEMLQRGDVKGKKLAIRIAYSK
What is the function of this protein?
Trans-enoyl reductase; part of the gene cluster that mediates the biosynthesis of the phytotoxin stemphyloxin II (PubMed:31553484).  The first step of the pathway is the synthesis of dehydroprobetaenone I by the polyketide synthase sthA and the enoyl reductase sthE via condensation of one acetyl-CoA starter unit with 7 malonyl-CoA units and 5 methylations (PubMed:31553484).  The C-terminal reductase (R) domain of sthA catalyzes the reductive release of the polyketide chain (PubMed:31553484).  Because sthA lacks a designated enoylreductase (ER) domain, the required activity is provided the enoyl reductase sthE (PubMed:31553484).  The short-chain dehydrogenase/reductase sthC then catalyzes reduction of dehydroprobetaenone I to probetaenone I (PubMed:31553484).  The cytochrome P450 monooxygenase sthF catalyzes successive epoxidation, oxidation (resulting from epoxide opening) and hydroxylation to install a tertiary alcohol in the decaline ring to yield betaenone C from dehydroprobetaenone I and betaenone B from probetaenone I (PubMed:31553484).  The FAD-linked oxidoreductase sthB is responsible for the conversion of betaenone C to betaenone A via an intramolecular aldol reaction between C-1 and C-17 to form the bridged tricyclic system in betaenone A (PubMed:31553484).  Finally, the cytochrome P450 monooxygenase sthD catalyzes the hydroxylation of C-15 to afford the final metabolite stemphyloxin II (PubMed:31553484).
What are the official names of this protein?
Trans-enoyl reductase sthE, Stemphyloxin II biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: ACRB_ECOLI
Sequence: MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFSRKNEDIEHSHTVDHH
What is the function of this protein?
(Microbial infection) Involved in contact-dependent growth inhibition (CDI), acts downstream of BamA, the receptor for CDI.  Its role in CDI is independent of the AcrA-AcrB-TolC efflux pump complex.
What are the official names of this protein?
Multidrug efflux pump subunit AcrB, AcrAB-TolC multidrug efflux pump subunit AcrB, Acridine resistance protein B.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CLPP_BARHE
Sequence: MSDPIKTALSLVPMVIEQTNRGERAYDIFSRLLKERIIFINGPVEDGMAMLVCAQLLFLEAENPKKEISLYINSPGGVVTSGMAIYDTMQFIRPPVSTLCMGQAASMGSLLLTAGAKGHRFTLPNARIMVHQPSGGFQGQASDIERHAQDIIKMKQRLNEIYVQHTGQNYDVIERTLDRDHFMTAEEAKQFGLVDDVIQYRAETEKEEKD
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF3_LIMRJ
Sequence: MSPKELAEAVNKRRTFAIISHPDAGKTTITEQLLLFGGVVREAGTVKARKTGNFAKSDWMEIEKKRGISVTSSVMQFDFQGKRINILDTPGHEDFSEDTYRTLMAVDSAVMVIDSAKGIEPQTKKLFQICKMRGIPIFTFMNKFDRDAREPLDLLNEVEDVLGIETYPINWPIGSGHQFKGIYDRFNHRVALTHPADENNPYLPLDEDGNVEGDNPLAGDGEWQDAMDGMELVEVAGNELDQEKIAKGDQTPVFFGSALTNFGVQTFLETYLQFAPAPSDHKTEDGDVVKPLDPEFSGFVFKIQANMNPRHRDRIAFVRICSGEFDRGMDVTLSRTKKPMRLSNVTEFMADTRENVETAVAGDIIGLYDTGNFQIGDSIYNGKKDIQFEKLPQFTPELFVRVSAKNVMKQKSFHKGINQLVQEGAVQLYRSYSTGDYILGAVGQLQFEVFKFRMQNEYNSEVVMEPMGTKTARWIDPDQLDEKMSSSRNILVKDIHDQPLFLFENQFAENWFKQKYPDVKLTAKL
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDRP_GEOSW
Sequence: MNQRLVYVVSDSGGETAELVVRAAASQFYNSHIQLKRVPYVEDKTMLAEVVALAKMNQAIIAFTLVVPEMRQFLIEEAAREGVVAYDIIGPLIEKMSDLFKLTPRYEPGQVRVLDEDYFKKIEAIEFAVKYDDGRDPRGILRADIVLIGVSRTSKTPLSQYLAHKRLKVANVPIVPEVEPPEQLFKVPPEKCFGLKISPEKLLSIRRERLKSLGLNDQAIYANMDRIKEELAYFDGIVKKIGCDVIDVTNKAVEETANIIMKKRRL
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: SYA_WOLPM
Sequence: MKLNEIRERFIKFFVNNDHEQVSSSPLIPEHDPTLMFTNAGMVQFKNIFTGAQKTEMKRAVSSQKCLRAGGKHNDLENVGYTTRHHTFFEMLGNFSFGDYFKETAIEFAWEFITKELSLDKNRLSITVYHTDDEAYEIWRKISGFSSDKIIRITTDDNFWSMGSTGPCGPCSEIFYDHGSPNLQEGDRIVEIWNLVFMEFNKDEEGNLHKLPKKCIDTGMGLERIAAVMQNVHDNYDIDLFSALISKSQEYCGRTENKIAHKIIADHLRAAAFLIAEGVLPGNEGRNYVLRRLIRRATRYIHLLGYNDSLLHRIFPVLIDSTSSAYMGAELVRAKSLIETTLKSEEENFKDTLMKGINLLEKFTTDLKSGDTLPGESAFKLYDTYGFPLDITLDVLKEKKINFDQKGFDDAMGEQKERARAKWAGSGEKSVEQVWFDLINKFGKTKFVGYEFNEVSDAKILAIVSSKNEVIDSAKEGEKITIILDKTPFYGESGGQVGDTGSLIKSDRSIIIVENTNKVNDLYLHRCIVKFGSICKGNTVAASIDKERRQTLRRNHSATHLLHFTLRKILGDHVTQKGSLVAPDRLRFDFSHNTQMTQDQLFWVEDMVNSLIRENLSASTKIQSMNQAIDEGAMALFGEKYGNQVRVVKIGDSRELCGGTHVEHTGEIGLFKIVTESSVAFGVRRIEALTGQEAINYVRDNEINLKKVAEFVKAPVSEITSRLSILSQEHKKSETKIKNLYKKLVSAENIKSTEINGINFISHTFTDIPANVIREFVLQQQKPKTVIAFTATEKDKTVLIIKVSKDLINKISAKELISIAVKKNCGGNAELAQTGCDSNKIDDAITAIYSKITASKHSTSYHHEPSYRRGANKQRDT
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_SALPC
Sequence: MSITKDQIIEAVSAMSVMDVVELISAMEEKFGVSAAAAVAVAAGPAEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKDDAEALKKSLEEAGAEVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: ATPL_GLUOX
Sequence: MDVQAAHEFGISIAQAARDLGAGIAVFALAGVGMGLGNIFSTLISSVARNPASRPHVFGIGMLGFALTEAVALFALLIAFLILFA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MTM1_MYCGE
Sequence: MHHFNRAKKAKNNEFFTLIDEIENEVINYQKQFANKTIFCNCNDGKNSHFFQFFQTNFNQLQLKKLIGFSFNNLSQADKFTFDGNKVTKTKLKGNGDFSSDESIEVLKQADIVVTNPPFSLFQSFIDLLIQHNKQFLVLGLNAAVSYNHIFTYFKTNKLWFGYTVNKTMSFSVNSDYQLYNPKTSNFFTKNGKCFQKIAGISWFTNLGKPHYNPFLNTNCFYKNNEKNYPKFDWYDAIYVNKIKNIPMDWNGLMGVPLTFLNCYNPKQFELVDCLANPYATLDTLKTNAFVKLNQGDVRNVNGKRRYVRVIIKKQQI
What is the function of this protein?
Probably recognizes the double-stranded sequence 5'-CTAT-3' and methylates A-3 on only one strand; as the bacterial DNA is methylated on this sequence and this is the only type II methylase in the genome, it is probably responsible for all of the methylation on this site in the genome.
What are the official names of this protein?
Type II methyltransferase M.MgeORF184P, M.MgeORF184P, Type II methyltransferase M.MgeI, M.MgeI.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family.
Protein: YVAM_VACCC
Sequence: MSEYFISRTSIWTVFMLPIMYGPIKSMIEISRSSYNVSVIVNTPIGVITNAASMAAYVNDLLLIHFLLSLVEFFNT
What are the official names of this protein?
Uncharacterized 8.6 kDa protein.
Protein: EX7L_BACCN
Sequence: MEKQYLTVTALTRYIKTKIEYDPHLQSVWLKGEISNFKYHSRGHMYFTLKDENARIAAVMFAGHNRNIKFRPEDGMKVLVKGKISVYEASGSYQIYVHDMQPDGVGNLHLAYEQLKVRLEEEGLFSRVYKQPIPAYAKTIGVITSPTGAAIRDIITTIKRRYPIGNVIVFPVLVQGEFAAPSIVQAIQTANEMNDIDVLIVGRGGGSIEELWAFNEEIVARAIFASKIPIISAVGHETDFTIADFVADLRAPTPTAAAELAVPNILEMQEKVLQRTLRLQRAMREIVHKRQERLQTLQKSYAFRYPRQIYEQKEEQLDRALEQLVLAKERYMEKKVNQLKQLSFYLEKHHPAQRISQTKIAIETLQKQLRREMQTVLQTKEFAFVRIAKQLEALSPLKVMMRGYGLVYSEKNQVLKSVKDVSAGDVVSVQLQDGILDCNVSSVKERESNGK
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_STAAM
Sequence: MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETHFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLAAHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XPT_ENTFA
Sequence: MKELVERIKNDGRVLGEGVLKVDSFITHQVDPELMEAMGNRFAEVFAEAGITKVITIEASGIAPALYAAQKLGVPMIFARKAKSLTMDEELLTASVYSFTKQVTSQISISRKFLSDADKVLIIDDFLANGQAAKGLVELCQQAGAKVEGIGIVIEKSFQDGRQLLEDMGLNVVSLARIASLSEGTVTFLEEDA
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS5_SYNSC
Sequence: MSLNLGLIDYGMGNLHSVEKCLERLDQGCSLINNSDDLEGIDALILPGVGAFDPAMANLRATGLVPHLLRWGQEDRPLLGICLGLQLLFEQSDEGSDPGLGLLGGRVTRLPSKSGERIPHMGWAPLKHHGTCPLLSSDASSEWVYFVHSYAAVPTDRNDLKASAPFGDQEVTAVVWRGRVGACQFHPEKSSDAGEQMLKRWLTWLRNGAEPCP
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: D1062_DICDI
Sequence: MIYNQALIEITKQGAVAVEEIKFSPPKLQTLISSIQNGGSPIINKNGSPAANALKNKQILQLQGQQQQQQQQQQNHSQQQHNNQSSVYSLNSLNPYYVQQVLCQLQKPHNFIKQVHVVVKNTPFGISMKSNDPQFNFHNYVIKATLLYDCDPPKMVDFIHNEPLQYVATVSEDGTEVVVDVKVGILSSQHQGSMFLAVLHISHTSVPSPSPNEPIMTILNNIGGNSIANLNSQLPNPIYNLCVVSHPIRIVSKVDHVKKEGIPILKKKTFHEILTDKLKKLQKFQDSQSKWIKNLYQQHLIEFDMEPYCSKKDQNNNNNNNNSNSNCQNGGGSICDDSSNSSTPSLSSYSNGNNKYNNNNNDSSESDESDDDDNNDDDDNDSIDFNISKQKNQQHLQQQLLNHQSKQQKVSSTNNNTTTTTSSSSASSIQQKQQPVQPQQQKQQNQSSNFQNSFNRVVEAFKYVPESERKDIITKMVEQLRSDDLEQLVATFMDELGVGDANSDVSSTKGGNNNNNNSIGCFCENCPSKKELERFQGLCMNFFVPQSTLNPMNNQQLLYSSLFSSSNDNNTQSQMNNSISVNNHHHHHHHQPNNSNLTNDLLQLPIV
What are the official names of this protein?
Developmental gene 1062 protein.
Protein: NFI_THEVO
Sequence: MLSVDYENFDLISYLYNLVRQIPDGMVSTYGDLAEALGDPVAARSVGFMLSINKEPDYIPCYKVVPHDGSVGNYTHPLGSAEKMRRLIRDGITITNGHISNFEKVRFREFKTDYPLRKLRELQFKIGRLYDDRNDYSLDTIAAFDVSYKETRGYASKVVYNKGKIGAYVYSSDSMFPYIPGYLAFKEFKFIRALYDNETMILIDGNGILHPRFAGLATHAGVSLKTASIGIAKHLINCTVKGSDLLISGVVAGKMIGHHTIVSPGNRINVEEAGRLIEQREGKEMRSLLRLAHNLTRLHIETNGNIARYDFSTRNTAIQSS
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA (By similarity).
What are the official names of this protein?
Bifunctional methyltransferase/endonuclease.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRX1B_RAT
Sequence: MYQRMLRCGAELGSPGGGSSGGAGGRLALLWIVPLTLSGLLGVAWGASSLGAHHIHHFHGSSKHHSVPIAIYRSPASLRGGHAGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNNDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPISQTTDDILVASAECPSDDEDIDPCEPSSGGLANPTRVGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAVVKEKQPSSAKSANKNKKNKDKEYYV
What is the function of this protein?
Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins (PubMed:9325340).  Plays a role in formation of synaptic junctions (By similarity).
What are the official names of this protein?
Neurexin-1-beta, Neurexin I-beta.
What is the protein family that this protein belongs to?
Belongs to the neurexin family.
What are the subcellular locations of this protein?
Presynaptic cell membrane; Single-pass type I membrane protein.
Protein: 20DD_HETMG
Sequence: SAALAGTIIAGASLGFQILDKVLGELGKVSRKIAIGVDNESIGSNTAWTXXXXW
What is the function of this protein?
Pore-forming protein that forms cations-selective hydrophilic pores of around 1 nm and causes cytolysis.  Pore formation is a multi-step process that involves specific recognition of membrane sphingomyelin (but neither cholesterol nor phosphatidylcholine) using aromatic rich region and adjacent phosphocholine (POC) binding site, firm binding to the membrane (mainly driven by hydrophobic interactions) accompanied by the transfer of the N-terminal region to the lipid-water interface and finally pore formation after oligomerization of monomers.
What are the official names of this protein?
Hemolytic toxin, Cytolysin, DELTA-stichotoxin.
What is the protein family that this protein belongs to?
Belongs to the actinoporin family. Sea anemone subfamily.
Protein: RISB_STRPN
Sequence: MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVNEKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: AROC_SALEP
Sequence: MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHDLDRRRPGTSRYTTQRREPDQVKILSGVFDGVTTGTSIGLLIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQMGDIPLEIKDWRQVELNPFFCPDADKLDALDELMRALKKEGDSIGAKVTVMASGVPAGLGEPVFDRLDADIAHALMSINAVKGVEIGEGFNVVALRGSQNRDEITAQGFQSNHAGGILGGISSGQHIVAHMALKPTSSITVPGRTINRMGEEVEMITKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRHRAQNADVKTEIPRW
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.