PharMolix/UniProtQA huggingface dataset:
Protein: CLPP_SALPK
Sequence: MSYSGERDNLAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIFLTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGISIYDTMQFIKPDVSTICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVKGRMNELMAHHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YK96_SCHPO
Sequence: MYANSRKRSNVDVHRHPYVVYGSPFDLEPSRINQGVPVWKQEARDERNRKRFHGAFTGGFSAGYFNTVGSKEGWQPKSWKSSRNENKSVHGMTIDDIMDEEDRADQELSKVYTSKINTIDTSIPIDDPLLREFSNRDDSIGEKMLKNLGWNGHDFVISPFQGYYDDTKLTNQAYHGIGYQADDVFQLERKPVGMAKNLRGGFGSGVLNDDGIEDQDIYDLGAPKMRYDKSINITKKVASPFTPVKHTFLSKKDRSKGKSIIKSQNCSDGLPPLPGFVVVFNLQSPFQNNWFPPPTIPEGWEPKLFTNSQGFSQKKAQTSNERLPLFAEKSETNSNGEASLPSDVNHGVKEDEGSWQLIDIETAKNAMSRKDNPYNDERAGIYEIFLKAHLMNMPRLLRDIDSRHLLEFTQTASLYRPMSKNLSMRFVSSFEASTKKESINSHSETDDSILRRPRTVVTFIPERLLCKRFNVALPYGQEKQKRKNISSIENVPIIAEIENKSIDSIDTRKLNRPQDIEEKPKAPQTLFSAIFGDD
What are the official names of this protein?
Uncharacterized protein C20H4.06c.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ACPS_RICB8
Sequence: MIIGVGTDIVQIPRIEKIIKLYPEIFPKRILNTEELKKFALLKKESHVTFLAKRFAAKEAISKAFGVGIGRGINFKDITLLNDELGKPIVKIDSLYTQKLPPFNIHLSLSDDYPICVAFVVVEKIIL
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_LEPCP
Sequence: MALTPADVSRIANLARLELSTAEQSDLLVQLNGFFGIVERMRAVDTTGVAPLYTPLSAVQDVSLRLRDDAVTETDQREANQKSAPAVEGGLFLVPRVIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: FATB_CINCA
Sequence: MATTSLASAFCSMKAVMLARDGRGMKPRSSDLQLRAGNAQTSLKMINGTKFSYTESLKKLPDWSMLFAVITTIFSAAEKQWTNLEWKPKPNPPQLLDDHFGPHGLVFRRTFAIRSYEVGPDRSTSIVAVMNHLQEAALNHAKSVGILGDGFGTTLEMSKRDLIWVVKRTHVAVERYPAWGDTVEVECWVGASGNNGRRHDFLVRDCKTGEILTRCTSLSVMMNTRTRRLSKIPEEVRGEIGPAFIDNVAVKDEEIKKPQKLNDSTADYIQGGLTPRWNDLDINQHVNNIKYVDWILETVPDSIFESHHISSFTIEYRRECTMDSVLQSLTTVSGGSSEAGLVCEHLLQLEGGSEVLRAKTEWRPKLTDSFRGISVIPAESSV
What is the function of this protein?
Plays an essential role in chain termination during de novo fatty acid synthesis.  High thioesterase activity for myristoyl-ACP.
What are the official names of this protein?
Dodecanoyl-[acyl-carrier-protein] hydrolase, chloroplastic, 14:0-acyl-carrier protein thioesterase, 14:0-ACP thioesterase, Acyl-[acyl-carrier-protein] hydrolase, CcFatB1, Myristoyl-acyl carrier protein thioesterase.
What is the protein family that this protein belongs to?
Belongs to the acyl-ACP thioesterase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS4_KOSOT
Sequence: MARYTGPVCKLCRREGFKLYLKGERCFTPKCAVVKRPFAPGQHGSATRKLTQYGMQLRSKQALKRMYGVLEKQFRRYFEIASRKSEETGTALIKVLESRLDNVVYRMGFASSRKQARQLVSHGHVLVNGRKVNKASYSVRPGDIIEIKEKSKAKVPVKEAIEASRNRTTPPWLEIDFDAARGTFVRFPEREEVDIPVDLQSIIELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RL17_STRZP
Sequence: MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTVEKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAERNGGYTRILKTEPRRGDAAPMAIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: MNMA_CORK4
Sequence: MRVMAAMSGGVDSSVAAARLVAEGHEVIGVHLALASTPTTLRVGSRGCCSLEDSGDARRVADALGIPFYVWDFSDRFREDVVDPFINSYEMGETPNPCLRCNEKIKFQALLDRGIALGFDAVATGHYARLKDGELRRAIDDNKDQSYVLGVLNDEQLAHCLFPLGDTRKPDIRKEAEAAGLVTASKPDSHDICFIPDGNTKAFLGNHIGVRSGDLKDQDGNVIGHHDGIYGFTIGQRKGLGLPGPAPDGKPRYVTDIDADTGTVTVGTRDDLRVGRLYADRLIRLDEHEGSTQECQVQVRAHGGVVDATVTIDDGVATIDLHSPLTGVARGQAAVIYRPDPDGDIVLGSGTICDTVSVSKLQPTTAGASSNS
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARAG_RALSO
Sequence: MSAFLEFRGISKVFPGVRALSEVSFGIECGRVHGLLGENGAGKSTLLKILGGDYQPDGGQIAVEGRPVAFPNARAALAAGIAVIHQELQTVPELTVMDNLLLGHLPSRGGFIRQGEAMAWTRAQLARIGVDLDPKARLKHLSIGQRQMVEICKAILRDARVIALDEPTSSLSVRETDILFRLVKDLRAQGRALIYISHRLDEIFALCDGCTIFRDGRKVADFRSMADVTREQLVAQMVGRQIDDIFGYRPRAPGDVRLRVEGLMGPKLAEPASFAVRRGEIVGLFGLVGAGRSELARLVYGADRKTAGTVVLDGEPIRIRAVADAIRQGIVLCPEDRKEEGIIGCRSVSENINISCRRNRRPGWGGFNLFVDDRQEAKTADHYIARLRIKTPHRDQPIRLLSGGNQQKAILARWLAEDGMRVLIIDEPTRGIDVGAKNEIYQVLYELAERGVAVLMISSELPEILGVADRVLVMSEGRIAGELPRAQATEHAVLNLALRPRRDPCVAAQAA
What is the function of this protein?
Part of the ABC transporter complex AraFGH involved in arabinose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Arabinose import ATP-binding protein AraG.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y1566_LISMH
Sequence: MTFKGFSKKDFKTMQIPGLEARMSGIQTDIQPKFRAVGEELTTYLSAKLGDEMFLHIARHQRRSVNPPESTWLAICHDKRGYKKHPHFQVGLFDNYLFIWLAFIYENEESKKIANRFLKEKKLLADLPDSFAISPDHTEEKTYPVHDGQLKATLERFRDVKKGEFLVGKIYLPDDSHLSPGKDFIKEAEMVLDELIPLYKASLQ
What are the official names of this protein?
UPF0637 protein LMHCC_1566.
What is the protein family that this protein belongs to?
Belongs to the UPF0637 family.
Protein: DCD_SHISS
Sequence: MRLCDRDIEAWLDEGRLSINPRPPVERINGATVDVRLGNKFRTFRGHTAAFIDLSGPKDEVSAALDRVMSDEIVLDEGEAFYLHPGELALAVTLESVTLPADLVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSFEPLSGPAARPYNRREDAKYRNQQGAVASRIDKD
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: CLD2_HUMAN
Sequence: MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTGITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVAGGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGIILCFSCSSQRNRSNYYDAYQAQPLATRSSPRPGQPPKVKSEFNSYSLTGYV
What is the function of this protein?
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
What are the official names of this protein?
Claudin-2, SP82.
What is the protein family that this protein belongs to?
Belongs to the claudin family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Protein: NAC25_ARATH
Sequence: MENMGDSSIGPGHPHLPPGFRFHPTDEELVVHYLKKKADSVPLPVSIIAEIDLYKFDPWELPSKASFGEHEWYFFSPRDRKYPNGVRPNRAATSGYWKATGTDKPIFTCNSHKVGVKKALVFYGGKPPKGIKTDWIMHEYRLTDGNLSTAAKPPDLTTTRKNSLRLDDWVLCRIYKKNSSQRPTMERVLLREDLMEGMLSKSSANSSSTSVLDNNDNNNNNNEEHFFDGMVVSSDKRSLCGQYRMGHEASGSSSFGSFLSSKRFHHTGDLNNDNYNVSFVSMLSEIPQSSGFHANGVMDTTSSLADHGVLRQAFQLPNMNWHS
What is the function of this protein?
Transcription factor of the NAC family.  May be associated with anther development and pollen production (Probable).  Required for normal seed development and morphology (PubMed:18849494).
What are the official names of this protein?
NAC transcription factor 25, AtNAC025.
What are the subcellular locations of this protein?
Nucleus.
Protein: HDOX_STAAB
Sequence: MKFMAENRLTLTKGTAKDIIERFYTRHGIETLEGFDGMFVTQTLEQEDFDEVKILTVWKSKQAFTDWLKSDVFKAAHKHVRSKNEDESSPIINNKVITYDIGYSYMK
What is the function of this protein?
Allows bacterial pathogens to use the host heme as an iron source.  Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.
What are the official names of this protein?
Heme oxygenase (staphylobilin-producing), Heme-degrading monooxygenase, Iron-regulated surface determinant, Iron-responsive surface determinant.
What is the protein family that this protein belongs to?
Belongs to the antibiotic biosynthesis monooxygenase family. Heme-degrading monooxygenase IsdG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_LACP7
Sequence: MYSFEDIKVFDPELADSITMEIARQNDHIELIASENFVSKAVMAAMGSPLTNKYAEGYPGKRYYGGCEFVDIAENLAIERAKKLFGCTYANVQPHSGAQANMAVFFALLQPGDTVMGMNLAHGGHLTHGSPVNFSGSYFNIVPYGVDDNGFIDYEEVEKIAKECKPKLIVAGASAYARKIDFKRFREIADLVGAYLMVDMAHIAGLVAAGYHQSPIPYAHVTTTTTHKTLRGPRGGMILSSEEFAEEHKLNKSIFPGTQGGPLMHVIAAKAICFKEALDDSFKDYAGKIISNAGALANELTARGFNLVSGGTDNHLMLIDLQNMNITGKEAEHILDEANITCNKNTVPNDPASPFVTSGIRLGTPAITTRGFNEKDMAVVAEAISLVVKDVDKNKEQAKALVKMLTDAYPLY
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_BUCAP
Sequence: MPRRRIISTRKILPDPKFSSELLAKFINILMVDGKKSIAEVIVYTALKNLSERTEKKELEAFEIALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWIVDSARKRGDKSMALRLSNELYDAVENKGTSVKKKEEVHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RUFY3_HUMAN
Sequence: MSALTPPTDMPTPTTDKITQAAMETIYLCKFRVSMDGEWLCLRELDDISLTPDPEPTHEDPNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGPLELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANFCMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEEMERVKEESSYILESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLRALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQSEKDLVKQAKTLNSAANKLIPKHH
What is the function of this protein?
Plays a role in the generation of neuronal polarity formation and axon growth (By similarity).  Implicated in the formation of a single axon by developing neurons (By similarity).  May inhibit the formation of additional axons by inhibition of PI3K in minor neuronal processes (By similarity).  Plays a role in the formation of F-actin-enriched protrusive structures at the cell periphery (PubMed:25766321).  Plays a role in cytoskeletal organization by regulating the subcellular localization of FSCN1 and DBN1 at axonal growth cones (By similarity).  Promotes gastric cancer cell migration and invasion in a PAK1-dependent manner (PubMed:25766321).
What are the official names of this protein?
Protein RUFY3, RUN and FYVE domain-containing protein 3, Rap2-interacting protein x, RIPx, Single axon-regulated protein, Singar.
Protein: DAPB_DESVM
Sequence: MSTSIIVTGAGGRMGSTICRMAQEDPVLTLAAVVERPERLASLDVWKCPSGSDPDAVFATVPGGVVVDFTSPEASMANARAAARAGVSHVIGTTGLTAEQKAELADLARTARIFWAPNMSIGVNVLLKILPQLVQQLGEQYDLEMVELHHNRKKDSPSGTALRLAECLAEARGWNLPDVANYHREGIIGERPKDEIGIQTIRGGDVVGVHTIYAMGPGERIEITHQAHSRENFAQGALRAAKWLPQQQPGTLYSMLDML
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRQ_ECO81
Sequence: MRLTVKQVTWLKVCLHLAGLLPFLWLVWAINHGGLGADPVKDIQHFTGRTALKFLLATLLITPLARYAKQPLLIRTRRLLGLWCFAWATLHLTSYALLELGVNNLALLGKELITRPYLTLGIISWVILLALAFTSTQAMQRKLGKHWQQLHNFVYLVAILAPIHYLWSVKIISPQPLIYAGLAVLLLALRYKKLLSFFNRLRKQVHNKLSL
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL24_STREM
Sequence: MFVKKGDKVRVIAGKDKGVEAVVLKALPKVNKVIVEGVAIIKKHQKPNSENPQGAIVEKEAPIHASNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: DCUP_NEIG2
Sequence: MTLLKNDTFLRALLKQPVEYTPIWMMRQAGRYLPEYKATRAKAGSFLDLCKNTGLATEVTIQPLERFDLDAAILFSDILTVPDAMGLGLYFAEGEGPKFAHALQHESDIAKLHVPDMEKLQYVFDAVTSIRKALDGRVPLIGFSGSPFTLACYMVEGGGSKEFRTIKTMMYSRPDLLYKILDTNAQAVTAYLNAQIDAGAQAVQIFDTWGGVLSDAAFKEFSLKYIRQIVAGLKRESEGRRVPVIVFAKGGGLWLESMVQIGADALGLDWTCNIGEARRRVGNQVALQGNFDPSALFGTPESIRTEVARILTGYGHGSGHVFNLGHGINQHADPEHAKILVDTVHELSRQYHGG
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOXL1_MOUSE
Sequence: MALAGAGSQLRTLVWSACLCVLVHGQQAQPGQGSDPGRWRQLIQWENNGQVYSLLNSGSEYVPAGPQRGETSSRVLLAGAPQTSQRRSQGGPRRRQAPSLPLPGRVGSDTVRGQTRHPFGFGQVPDNWREVAVGDSTGMARARTSVSQQRHGGSASSSVSASAFATTYRQPSPYPQQFPYPQAPFVNQYENYDPASRTYEQGYVYYRGAGGGMGAGAAAVASAGVIYPFQPRARYEDYGGGGGEEQPEYPAQGFYPAPERPYVPQPQPQPQPQPQPQPQPSDGLDRRYSHSLYNEGTPGFEQAYPDPSTDVSQAPAGAGGTYGGAGDPRLGWYPPYAANVPPEAYVPPRAVEPQPPFRVLEPPYLPVRSSDAPSQGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATDYDLRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDASTGKKVAEGHKASFCLEDSTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSTTNCKIVQS
What is the function of this protein?
Active on elastin and collagen substrates.
What are the official names of this protein?
Lysyl oxidase homolog 1, Lysyl oxidase 2, Lysyl oxidase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the lysyl oxidase family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: PCYA_SPHSK
Sequence: MTEKKERIDVHAYLAEFDDIPGTRVFTAQRARKGYNLNQFAMSLMKAENRERFKADESAYLDEWNLTPAAKAAVLARDYNAMIDEGGNVYFLSKLFSTDGKSFQFAAGSMTGMTQEEYAQMMIDGGRSPAGVRSIKGGY
What is the function of this protein?
Responsible for the aromatic ring fission of protocatechuate.
What are the official names of this protein?
Protocatechuate 4,5-dioxygenase alpha chain, 4,5-PCD.
Protein: ACSA_PSEU2
Sequence: MSAASLYPVRPEVAATTLTDEATYKAMYQQSVVNPDGFWREQAQRLDWIKPFSVVKQTSFDDHRVDIKWFADGTLNVAYNCLDRHLEERGDSIAIIWEGDDPSEHREITYRELHAEVCKFANALRGQDVHRGDVVTIYMPMIPEAVVAMLACARIGAIHSVVFGGFSPEALAGRIIDCSSKVVITADEGLRGGKKTALKANVDRALTNPETSSVQKVIVCKRTGGEIEWNRHRDIWYHSLLEVASSTCAPKEMGAEESLFILYTSGSTGKPKGVLHTTAGYLLYAALTHERVFDYRPGEVYWCTADVGWVTGHSYIVYGPLANGATTLLFEGVPNYPDITRVSKIIDKHKVNILYTAPTAIRAMMAEGTKSVEGADGSSLRLLGSVGEPINPEAWAWYYNTVGKQNCPIVDTWWQTETGGILISPLPGATALKPGSATRPFFGVIPALVDNLGNLIEGAAEGNLVILDSWPGQSRSLYGDHDRFVDTYFKTFRGMYFTGDGARRDEDGYFWITGRVDDVLNVSGHRMGTAEIESAMVAHPKVAEAAVVGVPHDLKGQGIYVYVTLNGGEEPSDALRTELRNWVRKEIGPIASPDFIQWAPGLPKTRSGKIMRRILRKIATAEYDALGDISTLADPGVVQHLIDTHKTMNAA
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: FUT10_CHICK
Sequence: MVRMRRKRLWASCICFAAFFFLLVTLQVITELGNSENKAPAVSSLHSGPLKPDERHASQLKKNELYSNFRTEPDTDHYPILLWWSPLTGETGRSGQCGEDVCFFTINKTYQHSQMTRAFLFYGTDFSIDSLPLPRKDHHDWALFHEESPKNNYKLFHEPAITLFNHTATFSRHSHLPLTTQYLESIEVLRSLRHMIPVQMKNSLRKRLAPLVYVQSDCNAPSDRDSYVRELMCHIEVDSYGECLHNRDLPQHLRNPSAMDDGNFYKILAQYKFILAFENAICEDYITEKLWRPLMLGVVPVYFGSPSIIDWLPSNKSAILVSSFSHPRELARYIKTLDQNDQEYEAYLEWKLKGDISNPRLLTAMKERKWGVQDVTQDNYIDTFECMVCNRVWENIRREEKGWLPQRWSAQVNHLNCPKPEAFWFSSSNPSQSSLQEMWIASFEQSKKEAWALRQLVERNRNFTTQEFWMLVFKQ
What is the function of this protein?
Probable fucosyltransferase.
What are the official names of this protein?
Alpha-(1,3)-fucosyltransferase 10, Fucosyltransferase X, Fuc-TX, FucT-X, Galactoside 3-L-fucosyltransferase 10, Fucosyltransferase 10.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 10 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Protein: MOAC_ECOL6
Sequence: MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMIIDGRHHKGDVFATARIAGIQAAKRTWDLIPLCHPLMLSKVEVNLQAEPEHNRVRIETLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEADD
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: RPOS_SALT1
Sequence: MSQNTLKVHDLNEDAEFDENGVEAFDEKALSEEEPSDNDLAEEELLSQGATQRVLDATQLYLGEIGYSPLLTAEEEVYFARRALRGDVASRRRMIESNLRLVVKIARRYGNRGLALLDLIEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERAIMNQTRTIRLPIHIVKELNVYLRTARELSHKLDHEPSAEEIAEQLDKPVDDVSRMLRLNERITSVDTPLGGDSEKALLDILADEKENGPEDTTQDDDMKQSIVKWLFELNAKQREVLARRFGLLGYEAATLEDVGREIGLTRERVRQIQVEGLRRLREILQTQGLNIEALFRE
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.
What are the official names of this protein?
RNA polymerase sigma factor RpoS, Sigma S, Sigma-38.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. RpoS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_SYNPW
Sequence: MPSMTDSTAIALLSGGLDSATAAALAQEAGCRVIGLSFDYGQRHRRELQAAAAIAEALNLAEHHTISVNLASWGGSSLTDSAQALPVDGVQDGVIPSTYVPGRNTVFISIGLSLAEARGADRLVLGVNAVDYSGYPDCRPDYLDAFQTLADLSSKVGREGRGPRLWAPLVEWSKQKIVEEALRLGVPIERSWSCYSGGDHPCGVCDSCRIRDAALQAAGRPDLCSSASR
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RPRX_BACFR
Sequence: MKKSTIWILGIIMGLSFLSLLYLQVSYIEEMVKMRKEQFNTSVRNALFQVSKDVEYDETQRWLLEDITEAERRALAQSSSTTEQKNGLIQQSERYRFKSPDGTLYSEFELKMITTEPSKVPKAMISERHGRNTIPQTSRSLTDAIKNRYMYQRFLLDDVALRMIYKASDKSIGERVNFKKLDNYLKSNFINNGVELLYHFSVIDKDGREVYRCSDYEDGGSEDSYTQPLFQNDPPAKMSIVKVHFPGKKDYIFDSVSFMIPSMIFTIVLLITFIFTIYIVFRQKKLTEMKNDFINNMTHEFKTPISTISLAAQMLKDPAVGKSPQMFQHISGVINDETKRLRFQVEKVLQMSMFDRQKATLKMKELDANELITGVINTFALKVERYNGKITSNLEATNPVIFADEMHITNVIFNLMDNAVKYKKPEEDLVLNVRTWNEPGKLMISIQDNGIGIKKENLKKVFDKFYRVHTGNLHDVKGFGLGLAYVKKIIQDHKGTIRAESELNVGTKFIIALPLLKND
What is the function of this protein?
Member of the two-component regulatory system RprX/RprY.  May activate RprY by phosphorylation.
What are the official names of this protein?
Sensor protein RprX.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DNAJ_CHLCH
Sequence: MKKDYYETLGVTRSSNKDDIKKAYRKLAVQYHPDKNPGNKEAEEHFKEVNEAYEVLSNDDKRRRYDQFGHAGVGSSAASGGGGAYAGGADFSDIFSAFNDMFTGGGARRGGSPFGGFEDAFGGGGGGGARRRASSGIHGTDLKIRLKLTLEEIAKGVEKTLKVKRQVPCEVCNGTGSKTGATETCQTCHGSGEVRQVSKTMFGQFVNIAACPTCGGEGRTIKERCTACYGEGIKLGETTVKINVPAGVENGNYMTMRGQGNAGPRGGAAGDLIVVFEEIHHETFTRNGHDVIYNLAVSYPDMVLGTKVEVPTLDGAVKLTIPAGTQPETMLRIQGHGIGHLKGGGRGDQYVKVNVFVPKEVSHQDKELLKDLRKSSNLCPNAHHDSESKSFFEKARDIFS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.