PharMolix/UniProtQA huggingface dataset:
Protein: SECA1_STAEQ
Sequence: MGFLSKIVDGNKKEIKRLGKLADKVLALEEDTAILTDEEIREKTKSFQKELAEIEDVKKQNDYLDKILPEAYALVREGSKRVFNMIPYKVQVMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSSQSEEMAELYNYLGLTVGLNLNSKSTEEKREAYAQDITYSTNNELGFDYLRDNMVNYAEERVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKAEDDYNYDEKTKAVHLTEQGADKAERMFKVDNLYDVQNVEVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVAIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRKDNSDLIYISQKGKFDAVVEDVVEKHKKGQPVLLGTVAVETSEYISNLLKKRGVRHDVLNAKNHEREAEIVSNAGQKGAVTIATNMAGRGTDIKLGDGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDRGDSRFYLSLQDELMVRFGSERLQKMMNRLGMDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNEIIDSEESSQVVNAMLRSTLQRAINHFINEEDDNPDYTPFINYVNDVFLQEGDLQDTEIKGKDSEDIFEIVWSKIEKAYAQQQETLGDQMSEFERMILLRSIDTHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKYILKSVVQFEDDVEREKSKSFGEAKHVTAEDGKEKAKPQPIVKGDQVGRNDPCPCGSGKKYKNCHGKA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: CSEB_STRAW
Sequence: MAEQTHVLFVEDDDVIREATQLALERDGFAVTAMPDGLSGLEAFRANRPDIALLDVMVPGLDGVSLCRRIRDESTVPVIMLSARADSIDVVLGLEAGADDYVTKPFDGAVLVARIRAVLRRFGHASGPNSRPAEDSSAPDGGVLTFGELEIDTEGMEVRRSGQPVALTPTEMRLLLEFSSAPGTVLSRDKLLERVWDYGWGGDTRVVDVHVQRLRTKIGQDRIDTVRGFGYKLKA
What is the function of this protein?
Member of the two-component regulatory system CseB/CseC involved in the stability of the cell envelope.  CseB activates transcription of RNA polymerase sigma-E factor, in response to changes in the cell envelope (By similarity).
What are the official names of this protein?
Transcriptional regulatory protein CseB.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_FRATN
Sequence: MSLENKNIIITAGGTGGHIYPALAIAELLRQNKANVTWVGTPNSMEASIVPEYFNIQFIKSSGVRRKGIIKKITFPLKLAYNTLRSRSLLKKLKADLVIGFGGYVSGPICLAAALINIPVIIHEQNAKIGLTNRILAKFATTICLAFEIENLHKQFSSKQLAKTKLVGNPVRKDIVALNDKARIYTDSSTLKILVLGGSQGAKAINEIIPKLIRKSNEQGINIKVWHQTGKLSLEETKDAYKDISQNHIKDIAAFIDDMATAYNWADLVICRAGALTVSECAIAGLPAIFIPLPSAVDDHQFFNAQNIVNNNAGFCLRQQQMTLENLLAIIKPLNQDRSKLEQMSKMAKKTLIKNSSEQILDCVKKILNNK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL2_HYPNA
Sequence: MALKTFNPTSPGRRQLVLVDRSALHKGKPVKALTQGLSSKGGRNNQGRITVRHQGGGVKRLYRQVDFKRTRWDIPATVERLEYDPNRTAFIALIKYQDGELSYIIAPQRLEVGDTVITSATADIKPGNTLPLKSIPVGTIIHNIELKPQKGAQMVRSAGTYAQLVGRDSGYAQIKLASGELRMVLDSCLATIGAVSNPDKMNEVSSKAGRNRHLGKRPTVRGVVMNPVDHPHGGGEGKSSGGRHPVSPWGKKTRGPKTRNNKVTDRLIIRRRNAKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RS6_ALKCK
Sequence: MRKYEIMYIIAPNLEESANKEIIERYNKVLTDNGAEILKVDEIGKKRLAYEINDFKDGFYVLLSVQANTEAINEFNRLIKINDNVIRVLVTKDEQ
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: QUEC_YERPA
Sequence: MKRAVVVFSGGQDSTTCLIQALQQYDEVHCITFDYGQRHRTEIDVARELALQLGATAHKVLDVGMLNELAVSSLTRDSIPVPSYDANADGALPSTFVPGRNILFLTLASIYAYQVQAQAVITGVCETDFSGYPDCRDEFIKALNHAIDLGIGRDIAFITPLMWLDKAETWALADYYQQLDLIRHHTLTCYNGIKGDGCGQCAACHLRAKGLASYMANKQQVILNLKQKVGLA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: PHT16_ARATH
Sequence: MANEEQGSILKALDVAKTQWYHVTAVVVSGMGFFTDSYDLFVISLITKLLGRIYYQVPGSSSPGSLPDGISAAVSGVAFAGTFIGQIFFGCLGDKLGRKRVYGLTLLIMTICSICSGLSLGRDPKTVMVTLCFFRFWLGFGIGGDYPLSATIMSEYSNKRTRGAFIAAVFGMQGIGILAAGAVSLLVSAVFESKFPSRAYILDGAASTVPQADYVWRIILMVGALPALLTYYWRMKMPETARYTALVSKNAEQAALDMTKVLNVDIEASAAKNDQARVSSDEFGLFSMKFLRRHGLHLLGTASTWFLLDIAFYSQNLFQKDIFTTIGWLPSAKTMNAIQELYMIAKAQTIIACCSTVPGYFFTVGFIDYMGRKKIQIMGFAMMTIFMLSLAIPYHHWTLPANRIGFVVLYSFTFFFSNFGPNATTFIVPAEIFPARIRSTCHGISAASGKAGAMVGSFGFSALVKALGMSNTLYIMAGINLLGLLLTFTIPETNGKSLEELSGETEPEKIKEKIVV
What is the function of this protein?
High-affinity transporter for external inorganic phosphate.
What are the official names of this protein?
Probable inorganic phosphate transporter 1-6, AtPht1;6, H(+)/Pi cotransporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. phosphate:H(+) symporter (TC 2.A.1.9) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PLY_XANCM
Sequence: MKPKFSTAAAASLFVGSLLVVGVACADPALEVATTGWATQNGGTKGGSKAAAANIYTVKTAAELKSALKASVGSNGRIIKISGIIDVSEGKPYTTTSDMKSRARLDIPTKTTLIGITSNAEIREGYFYVKANDVIIRNITIENPWDPEPVWDPDDGSAGNWNSEYDGLTVEGATNVWVDHVTFTDGRRTDDQNGTANGRPKQHHDGAMDVKKGANFVTISYSAFKSHEKNDLIGSSDSASSTDSGKLKVTIHNTLFENISARAPRVRFGQVHLYNNYHVGSTSNKVYPFSHAHGVGKESKIFSERNVFDISGVSSCDKIAADYGGSVYRDQGSLLNGKALTCSWNSNIGWTPPYTYSLLSADKVAADVKAKAGAGKL
What is the function of this protein?
Plays a role in bacterial invasion of plants.
What are the official names of this protein?
Pectate lyase, PL, PSTRU-3.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CCX1_ARATH
Sequence: MASLFSSRLGSQSLSLLINIFFIFLIFLHFASQTPPPSGSIQTLNSFAGGDSDSCSGGLASLDDHRSKCSYIRSQSKCGPQGYIDYLKIFFCIFGQSPVLGHLVLSAWLFVLFYLLGDTAASYFCPSLDSLSKVLKLSPTMAGVTLLSLGNGAPDLFSSVVSFTRSNNGDFGLNSILGGAFFVSSFVVGTICVLIGSRDVAIDRNSFIRDVVFLLVALCCLGLIIFIGKVTIWVALCYLSIYLLYVGFLSVSHFFDRKKRMSDQILRSREDLAEMGVSLLGYIAEEKLALPEKTTQEFKIVFEDSPKRHRSCFSVLVSIIGLPLYLPRRLTIPVVCEEKWSKPCAVVSTAIAPVLLTELYCSHYSGSQRNLILYIISGSIGLIVGILAYLTTEKSHPPKKFSLVWLLGGFTMSVTWTYMIAQELVSLLISLGNIFGISPSVLGLTVLAWGNSLGDLIANVTVAFHGGNDGAQIALSGCYAGPLFNTVIGLGVPLVISSLAEYPGVYIIPSDNSLLETLGFLMVGLLWALVIMPKKKMRLDKLVGGGLLAIYLCFLSLRLARVFGVLDTDR
What is the function of this protein?
Vacuolar membrane-localized H(+)-dependent K(+) and Na(+) transporter.
What are the official names of this protein?
Cation/calcium exchanger 1, AtCCX1, Protein CATION EXCHANGER 7.
What is the protein family that this protein belongs to?
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. Cation/calcium exchanger (CCX) subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: RPOZ_BRUC2
Sequence: MARVTVEDCVDKVENRFELVLLAGHRARQISQGVPITVDRDNDKNPVVALREIADETLSPDDLKEDLIHSLQKHVEVDEPEAAPAQIANAAEEIAEGIAEAGEEDVVTFDRMSEEELLAGIEGLVAPEKNDGF
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: TRUA_CHLTE
Sequence: MARSKRTIKMQIEYDGTGYSGWQRQPGDVVTVQGEIERVLERIMQEPVSIDGAGRTDSGVHARRQVASFATCSPMPLGRLIYSANSLLPSTIRINAMRQAPESFHARFSATSREYRYFLLEHPSAIDSRFAGCSHGKPDVGAMNRLALMLIGTHDFAAFSKETPDQYGTLCTVTAARWYRSGRFHVFRIEANRFLRSMVRFLVAGMIEVGMGRLEEGAFARMLESGHRPPKLKPADAAGLFLWKVRY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: TRMFO_LYSSC
Sequence: MTEQVVNVIGAGLAGSEAAWQIAKRGVKVRLYEMRPVKQTPAHHTDKFAELVCSNSLRANGLTNAVGVIKEEMRILDSVILKAADQCSVPAGGALAVDRHEFAGYVTEAVKNHPLVEVIHEEVTEIPEGITVIATGPLTSKALAEKIQGLTGLDYLYFYDAAAPIIEKDSIDMDKVYLKSRYDKGEAAYLNCPMTKEEFDRFRQALIEAEVVPLKEFEKEIYFEGCMPIEVMASRGEKTMLFGPMKPVGLEDPKTGKRPYAVVQLRQDDAAGTLYNIVGFQTHLKWGPQKEVLQLIPGLENVEIVRYGVMHRNTFINSPKVLEKTYQLREQKNIFFAGQMTGVEGYVESAGSGLIAGINAARLALGQEPIIFPFETALGSMARYITEAQSKNFQPMNVNFGIFPELPPGRRSKPERAEMHATRAISTIHNFVNSQTI
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDH7_ORYSJ
Sequence: MAQPAFLSALRSRLRSPQPQAPALPHLQPPRRGFHVELGAREKALLEEDTALKRFKSYKNSVKQVSKVGNILTGVVLFACAYEIVALANS
What are the official names of this protein?
Succinate dehydrogenase subunit 7, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein.
Protein: SCO11_ARATH
Sequence: MASALCRTASRLRSVQLFRRIRVSSDLLSASSPSPACISDALRHGDFSLPRSFFSLNCGIEMLKMDQRCLLSTSASDTTSKHDSGKPETKSSEKNEKSGGSESSDGGSDHKNERASGKDVRGGPVSWMSFFLLFATGAGLVYYYDTQKKRHIEDINKNSIAVKEGPSAGKAAIGGPFSLIRDDGKRVTEKNLMGKWTILYFGFTHCPDICPDELIKLAAAIDKIKENSGVDVVPVFISVDPERDTVQQVHEYVKEFHPKLIGLTGSPEEIKSVARSYRVYYMKTEEEDSDYLVDHSIVMYLMSPEMNFVKFYGKNHDVDSLTDGVVKEIRQYRK
What is the function of this protein?
Thought to play a role in cellular copper homeostasis, mitochondrial redox signaling or insertion of copper into the active site of COX.  Plays an essential role in embryo development.
What are the official names of this protein?
Protein SCO1 homolog 1, mitochondrial, Homolog of the copper chaperone SCO1 member 1, HCC1.
What is the protein family that this protein belongs to?
Belongs to the SCO1/2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: AGRG2_MOUSE
Sequence: MLFSGGQYSPVGRPEEVLLIYKIFLVIICFHVILVTSLKENGNSSLLSPSAESSLVSLIPYSNGTPDAASEVLSTLNKTEKSKITIVKTFNASGVKSQRNICNLSSLCNDSVFFRGEIVFQHDEDHNVTQNQDTANGTFAGVLSLSELKRSELNKTLQTLSETYFIVCATAEAQSTVNCTFTVKLNETMNVCAMMVTFQTVQIRPMEQCCCSPRTPCPSSPEELEKLQCELQDPIVCLADQPHGPPLSSSSKPVVPQATIISHVASDFSLAEPLDHALMTPSTPSLTQESNLPSPQPTIPLASSPATDLPVQSVVVSSLPQTDLSHTLSPVQSSIPSPTTPAPSVPTELVTISTPPGETVVNTSTVSDLEAQVSQMEKALSLGSLEPNLAGEMVNRVSKLLHSPPALLAPLAQRLLKVVDAIGLQLNFSSTTISLTSPSLALAVIRVNASNFNTTTFAAQDPTNLQVSLETPPPENSIGAITLPSSLMNNLPANDVELASRIQFNFFETPALFQDPSLENLTLISYVISSSVTNMTIKNLTRNVTVALKHINPSPDDLTVKCVFWDLGRNGGKGGWSSDGCSVKDKRMNETICTCSHLTSFGILLDLSRTSLPPSQMMALTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLIFLLDSWIALYNTRGFCIAVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCIVGWGIPAVVVSIVLTISPDNYGIGSYGKFPNGTPDDFCWINSNVVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFFAWGPVNVTFMYLFAIFNTLQGFFIFIFYCAAKENVRKQWRRYLCCGKLRLAENSDWSKTATNGLKKQTVNQGVSSSSNSLQSSCNSTNSTTLLVNSDCSVHASGNGNASTERNGVSFSVQNGDVCLHDLTGKQHMFSDKEDSCNGKSRIALRRTSKRGSLHFIEQM
What is the function of this protein?
Orphan receptor.  Could be involved in a signal transduction pathway controlling epididymal function and male fertility.  May regulate fluid exchange within epididymis.
What are the official names of this protein?
Adhesion G-protein coupled receptor G2, G-protein coupled receptor 64, Mouse epididymis-specific protein 6, Me6.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein.
Protein: RL1_RHOBA
Sequence: MGKKSKRYRAALEKQPKEMLPLGKAVEVLKTYDATKFDQTVEVHMRLGVDPNQADQIIRGSLVLPHGIGKTQRVIVFAKGDAAKAAEEAGADEVGQEDLAKKIKDGWTDFDVCIAAPDMMGLVGPLGRVLGPRGLMPSPRAGTVTPDVGKVVSEYKAGKVEFRNDKGGNVHAMVGKMSFEANKLEENIASFVDFISAMKPQSIKGTYIKGVAICATMTPSVRVAT
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: ERA_DESVH
Sequence: MNQTTHRCGWVALIGPPNAGKSTLLNALIGQKVAIVTSKPQTTRNQIVGILSRKDAQVVFMDTPGIHQLRGRLNKMLLQTAWQSMNAADALIVMLDGDLYIRKPDLLDRDIAPLVEPIAAETRPVVVVVNKIDLFRDKSKMLPLLERLSAMWPKAEVFPASALNKDGMDHLLRLIVGYMPEGPALYPEDQISTLPVRFMTAEIVREKVFNKLRQELPYSTAVDIEQWEEEEGRDQVIVNAVIYVARPSHKSMVIGKGGATIKEIGIEARKDIQELLEKRVHLELWVKVREGWTEDLGFMRSLGLSPDE
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: MURA_NITEC
Sequence: MQKLVIHGGSKLHGEISISGAKNAALPVLCASLLTAEPFAIQNIPHLRDVTTMLALLEQIGVRILTNEPGTTELSAANITNPTASYDMVKTMRAAILVLGPLLARTGQAHISLPGGCAIGMRPVDQHIKGLQAMGAEINIEQGYILAQVGRLSGARIAMDVVTVTGTENLMMAATLASGTTILENAAREPEVIDLANCLIGMGAKIEGAGNDIIIIEGVDRLHGGSHVVMPDRIETGTFLTAVAACGGDVTLIGTRADTLDVVLGKLAEAGADIDIGGDWIRLCMQQRPQPVSLRTAPYPAFPTDMQAQFMALNSIAGGTSIMTETIFENRFMHVQELTRLNADIQVEGNTAIVHGIPQLDGASVMATDLRASACLIIAGLIAQGETIVDRIYHLDRGYEQIEQKLAQVGAHIKRIN
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAG8_ARATH
Sequence: MASHHHHNHNHVCSRHQNHHNNTPQFATSPNCCNKSNHPSPPPAEDNLLHLVATYLQNHQQETQCSCETSCQNFNVIRSQNRVLRQHKNVPREYDQVVLSCLLRKIDDLESSLNKFSSFYDKRRDRHSTLRDSAARVIQTHFRSYLVHRSISFRQLKELAMIKASFLSLKSSVSGKLIFPFKVVSRKATDLLLQLDSIQGRIDPMIRSSKRSLSRDLVRFVQYVDDCVVKRYGFVVKSGSGIKLNGKKPQGFGTSSEDEDNNADMSDDSEEVPVSSIDKRKVASSKSRTGVVIEGDVVKPPVMKFVVLDKNRNVCQVYGNRHDLTSSAEDDSVDGDEETLVMSRDNGRKQSLKARNGVSVKGGGGKTTRVVKTVSFDENGNVCKVYGDTHDLTSSAEDDDSVDVGEETLVMCRDEGKRRSSKTGSRVLVKGSGGKTNRVVKTVSFDENGNVYKAYGDTPESSIISEEDDSTSGSNEGNGEEKGNVNEVEEIKYVPKENESFEEEEEKETDSENEVSSSEGSEGDKRVTKKEVQHQKGSLMFSPPLPLKMEP
What is the function of this protein?
Co-chaperone that regulates diverse cellular pathways, such as programmed cell death and stress responses.
What are the official names of this protein?
BAG family molecular chaperone regulator 8, chloroplastic, Bcl-2-associated athanogene 8.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: G17M_BACSU
Sequence: MKPVVKEYTNDEQLMKDVEELQKMGVAKEDVYVLAHDDDRTERLADNTNANTIGAKETGFKHAVGNIFNKKGDELRNKIHEIGFSEDEAAQFEKRLDEGKVLLFVTDNEKVKAWA
What are the official names of this protein?
General stress protein 17M, GSP17M.
Protein: GCR_PIG
Sequence: MDPKESLTPPSREEIPSSVLGRERAHVMDFYKSLRGGTPVKVSAASPSLAAVSQPDSKQQRLAVDFPKGSGSNAQQPDLSKAVSLSMGLYMGETETKVMGSDLGFPQQGQISLSSGETDFRLLEESIANLSRSTSVPENPKSSASAAGPAAPAEKAFPKTHSDGAPEQPNVKGQTGTNGGNVKLFTTDQSTFDIWRKKLQDLELPSGSPGKETSESPWSSDLLIDENCLLSPLAGEEDPFLLEGSSTEDCKPLVLPDTKPKVKDNGELILPSPNSVPLPQVKTEKEDFIELCTPGVIKQEKLGPAYCQASFSGANIIGGKMSAISVHGVSTSGGQLYHYDMNTAASLSKQQEQKPLFNVIPPIPVGSENWNRCQGSGDDNLTSLGTLNFSGRSVFSNGYSSPGMRPDVSSPPSSSSAATGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENSANKTIVPATLPQLTPTLVSLLEVIEPEVLYAGYDSSIPDSTWRIMTALNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMVFALGWRSYRQSSASLLCFAPDLVINEQRMALPCMYDQCRHMLYVSSELQRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHDVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQLPKYSSGNIKKLLFHQK
What is the function of this protein?
Receptor for glucocorticoids (GC).  Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors.  Affects inflammatory responses, cellular proliferation and differentiation in target tissues.  Involved in chromatin remodeling.  Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay.  Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth.  Mediates glucocorticoid-induced apoptosis.  Promotes accurate chromosome segregation during mitosis.  May act as a tumor suppressor.  May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic gene expression.
What are the official names of this protein?
Glucocorticoid receptor, GR, Nuclear receptor subfamily 3 group C member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=After ligand activation, translocates from the cytoplasm to the nucleus (By similarity). In the presence of NR1D1 shows a time- dependent subcellular localization, localizing to the cytoplasm at ZT8 and to the nucleus at ZT20 (By similarity). Lacks this diurnal pattern of localization in the absence of NR1D1, localizing to both nucleus and the cytoplasm at ZT8 and ZT20 (By similarity).
Protein: ECE2_BOVIN
Sequence: MSVALQELGGGGNMVEYKRATLRDEDAPETPVEGGASPDAVEAGFRKRTSRLLGLHTQLELVLAGVSLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAERKTQRFYLSCLQVERIEELGAQPLRDLIDKIGGWNVTGPWDQDNFMEVLKAVAGTYRATPFFTVYVSADSKSSNSNIIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGQPTSTREQMRQVLELEIQLANITVPQDQRRDEEKIYHKMSIAELQALAPSMDWLEFLSFLLSPLELGDSEPVVVYGTDYLQQVSELINRTEPSVLNNYLIWNLVQKTTSSLDHRFESAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRAAFEEALGHLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYTCNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACIEEQYSQYQVNGEKLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNSGQLCEVW
What is the function of this protein?
Converts big endothelin-1 to endothelin-1.  Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides (By similarity).  May play a role in amyloid-beta processing (By similarity).
What are the official names of this protein?
Endothelin-converting enzyme 2, ECE-2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M13 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein. Cytoplasmic vesicle, secretory vesicle membrane.
Protein: Y227_STRPJ
Sequence: MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKIYQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKAAKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTAVADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGVVKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPAVGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDEGMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKTTAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN
What are the official names of this protein?
UPF0210 protein SPN23F02270.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: YHBE_SHIFL
Sequence: MKQQAGIGILLALTTAICWGALPIAMKQVLEVMEPPTIVFYRFLMASIGLGAILAVKKRLPPLRVFRKPRWLILLAVATAGLFGNFILFSSSLQYLSPTASQVIGQLSPVGMMVASVFILKEKMRSTQVVGALMLLSGLVMFFNTSLVEIFTKLTDYTWGVIFGVGAATVWVSYGVAQKVLLRRLASPQILFLLYTLCTIALFPLAKPGVIAQLSHWQLACLIFCGLNTLVGYGALAEAMARWQAAQVSAIITLTPLFTLFFSDLLSLAWPDFFARPMLNLLGYLGAFVVVAGAMYSAIGHRIWGGLRKHTTVVSQPRAGE
What are the official names of this protein?
Uncharacterized inner membrane transporter YhbE.
What is the protein family that this protein belongs to?
Belongs to the EamA transporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y2432_ENT38
Sequence: MAGHSKWANTKHRKAAQDAKRGKIFTKIIRELVTAARLGGGDAGSNPRLRAAIDKALANNMTRDTLNRAIARGVGGDDDANMETIIYEGYGPGGTAVMVECLSDNRNRTVAEVRHAFTKTGGNLGTDGSVAYLFSKKGVISFDAGDEDAIMEAALEAGAEDVVTFDDGAIDVYTAWEEMGAVRDALAAMGLKADNAEVSMIPSTKADMDAETAPKLLRLIDMLEDCDDVQEVYHNGEISDEVAATL
What are the official names of this protein?
Probable transcriptional regulatory protein Ent638_2432.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.