PharMolix/UniProtQA huggingface dataset:
Protein: ATP8_ELEMA
Sequence: MERMDIIIWLLAVVIVLTTLMIFLHLKTLKIIRLLFPISKELSKKSCVFPWKKKWTKNYPPSSMYP
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: CPTP_MOUSE
Sequence: MDDSEKDFNLKVVLVSFKQCLTDKGEVLLDHYIAGWKGLVRFLNSLGAVFSFISKDVVAKLQIMERLRSSPQSEHYASLQSMVAYEVSNKLVDMDHRSHPRHPHSGCRTVLRLHRALHWLQLFLDGLRTSSEDARTSTLCSEAYNATLANYHSWIVRQAVTVAFCALPSRKVFLEAMNMESTEQAVEMLGEALPFIEHVYDISQKLYAEHSLLDLP
What is the function of this protein?
Mediates the intracellular transfer of ceramide-1-phosphate (C1P) between organelle membranes and the cell membrane.  Required for normal structure of the Golgi stacks.  Can bind phosphoceramides with a variety of aliphatic chains, but has a preference for lipids with saturated C16:0 or monounsaturated C18:1 aliphatic chains, and is inefficient with phosphoceramides containing lignoceryl (C24:0).  Plays a role in the regulation of the cellular levels of ceramide-1-phosphate, and thereby contributes to the regulation of phospholipase PLA2G4A activity and the release of arachidonic acid.  Has no activity with galactosylceramide, lactosylceramide, sphingomyelin, phosphatidylcholine, phosphatidic acid and ceramide.  C1P transfer is stimulated by phosphatidylserine in C1P source vesicles (By similarity).  Regulates autophagy, inflammasome mediated IL1B and IL18 processing, and pyroptosis, but not apoptosis (PubMed:29164996).
What are the official names of this protein?
Ceramide-1-phosphate transfer protein, CPTP, Glycolipid transfer protein domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the GLTP family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein. Nucleus outer membrane; Peripheral membrane protein.
Protein: CP9B1_DROME
Sequence: MSFVEICLVLATIGLLLFKWSTGTFKAFEGRNLYFEKPYPFLGNMAASALQKASFQKQISEFYNRTRHHKLVGLFNLRTPMIQINDPQLIKKICVKDFDHFPNHQTLNIPNERLVNDMLNVMRDQHWRNMRSVLTPVFTSAKMRNMFTLMNESFAQCLEHLKSSQPIAAGENAFELDMKVLCNKLSNDVIATTAFGLKVNSFDDPENEFHTIGKTLAFSRGLPFLKFMMCLLAPKVFNFFKLTIFDSTNVEYFVRLVVDAMQYREKHNITRPDMIQLLMEAKKESKDNWTDDEIVAQCFIFFFAAFENNSNLICTTAYELLRNLDIQERLYEEVKETQEALKGAPLTYDAAQEMTYMDMVISESLRKWTLSAAADRLCAKDYTLTDDEGTKLFEFKAGDNINIPICGLHWDERFFPQPQRFDPERFSERRKKDLIPYTYLPFGVGPRSCIGNRYAVMQAKGMLYNLMLNYKIEASPRTTRDMWESARGFNIIPTTGFWMQLVSRK
What is the function of this protein?
May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
What are the official names of this protein?
Cytochrome P450 9b1, CYPIXB1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: IF5A_HALSA
Sequence: MAKEQKEVRDLQEGNYVMMEDAACQINAYSTAKPGKHGSAKARIEAEGVFDGKKRSLSQPVDAKIWVPIVNRKQGQIVSKESDTVAQVMDLETYETVTMQIPGELDIQADENIEYLEFEGQRKILQE
What is the function of this protein?
Functions by promoting the formation of the first peptide bond.
What are the official names of this protein?
Translation initiation factor 5A, Hypusine-containing protein, eIF-5A.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMO_KLEAE
Sequence: MANGLKFSPRKTALALAVAVVCAWQSPVFAHGSEAHMVPLDKTLQEFGADVQWDDYAQMFTLIKDGAYVKVKPGAKTAIVNGKSLDLPVPVVMKEGKAWVSDTFINDVFQSGLDQTFQVEKRPHPLNSLSAAEISKAVTIVKAAPEFQPNTRFTEISLHEPDKAAVWAFALQGTPVDAPRTADVVMLDGKHVIEAVVDLQNKKILSWTPIKGAHGMVLLDDFVSVQNIINTSSEFAEVLKKHGITDPGKVVTTPLTVGFFDGKDGLQQDARLLKVVSYLDTGDGNYWAHPIENLVAVVDLEAKKIIKIEEGPVIPVPMEPRPYDGRDRNAPAVKPLEITEPEGKNYTITGDTIHWQNWDFHLRLNSRVGPILSTVTYNDNGTKRQVMYEGSLGGMIVPYGDPDVGWYFKAYLDSGDYGMGTLTSPIVRGKDAPSNAVLLDETIADYTGKPTTIPGAVAIFERYAGPEYKHLEMGKPNVSTERRELVVRWISTVGNYDYIFDWVFHDNGTIGIDAGATGIEAVKGVLAKTMHDPSAKEDTRYGTLIDHNIVGTTHQHIYNFRLDLDVDGENNTLVAMDPEVKPNTAGGPRTSTMQVNQYTIDSEQKAAQKFDPGTIRLLSNTSKENRMGNPVSYQIIPYAGGTHPAATGAKFAPDEWIYHRLSFMDKQLWVTRYHPTERYPEGKYPNRSAHDTGLGQYAKDDESLTNHDDVVWITTGTTHVARAEEWPIMPTEWALALLKPWNFFDETPTLGEKKK
What is the function of this protein?
Active on tyramine, tryptamine, beta-phenethylamine and dopamine.
What are the official names of this protein?
Primary amine oxidase, Copper amine oxidase, Monamine oxidase, Tyramine oxidase.
What is the protein family that this protein belongs to?
Belongs to the copper/topaquinone oxidase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HSLV_SHESA
Sequence: MTTIVSVRRNNQVVIAGDGQVSLGNTVMKGNAKKVRRLYHNKVLAGFAGGTADAFTLFERFESKLEMHQGHLLRSAVELAKDWRTDRMLRKLEAMLVVADAEASLIITGNGDVVQPEHDLVAIGSGGNYAQAAALALLQNTELSALEIAEKSLTIAGDICVFTNQFKTIEELNY
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7S_ALISL
Sequence: MAVKKPENLTFEAAIEELDSVVNQLESGDLPLEDALKKFERGISLARAGQEKLTQAEQRVDILLQADDNAELTPFDANDD
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_GEOSW
Sequence: MNELLIKAEQLQQAAKTLALLSTEEKNEALTRIAEALIKQKEWILQENEKDVALGKEQGLSPALIDRLQLTNERIEQIVDGVRQVADLPDPIGEIVEEWTRPNGLRIQTIRVPLGVIGMVYEARPNVTVDAASLCLKTGNAVLLRGSSSALHSNKALVHVMKEALRDSAIPADAIQLLEDTSREAAQQMFRLNGYLDVLIPRGGAGLIRSVIENATVPVLETGVGNCHIFIDESAQKQMAIDIVLNAKLQRPSVCNAVETVLIHQNWPYISELVETLHARGVELRGDSQLASSYSFIQQAAETDWSTEYLAPILAVKLVQNVKEAVDHINRYGTKHSEAIISEQNDNVRFFFQAIDAAVLYHNASTRFTDGEQFGYGAEIGISTQKLHARGPMGLRAITTTKSLVYGTGQIRS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_LEPBL
Sequence: MEPVHYSVQGNNILQIFTENFHKEDPVLFLDGTAGEGGHSLLFLKGFPNSKVILCDRDPVMLSRALARLVDFKERVVSIQTNFSEIDSNLLSSHGINDSPQGILLDLGISTFHLFHSGRGFSFKEAEPLDMRLTPNIGINAEDVINTYSKDRLMHIFYTYGEERWSKKIAEVIVERRKQNLISYTSELADLISKIIPRKLWPPGRHPATRIFQALRIEVNQELTHIEKGLDSLLNLLRPEGVIQVISFHSLEDRIVKNSLRNYAKQNGFELLTKKPILPSEEETKENPASRSAKLRVLRKTKSADKKYKKENSKEE
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEUP1_MACFA
Sequence: MENQAHNTMGTSPCEAELQELMEQIDIMVSNKKMDWERKMRALETRLDLRDQELANAQTCLDQKGQEVGLLRQKLDSLEKCNLAMTQNYEGQLQSLKAQFSKLTNSFEKLRLHQMKQNKVPRKELPHLKEELPFELSNLNQKLEEFRAKSREWDKQEILYQTHLISLDAQQKLLSEKCNQFQKQAQSYQTQLNGKKQCLEDSSSEIPRLICDPDPNCEIGERDEFIIEKLKSAVSEIALSRNKLQDENQKLLQELKMYQRQCQAMEAGLSEVKSELQSRDDLLRIIEMERLQLHRELLKIGECQNAQGNKKRLESSHLPSIKEPERKRKELFSVMQDQPNHEKELNKIRSQLQQEEEYHNSEQERMRNEISDLTEELHQKEITIATVTKKAALLEKQLKMELEIKEKMLAKEQVSDMKYKAVRTENTHLKGMMGDLDPGRYMSMDFTNREHSRHTSINKLEYENERLRNDLAKLRVNGKSTRTNQNTYEETGRYAYQSQIKVEKNEERLSHDCEPNRSTSPLPPLTFQTKEMTSPLVSDDDVFPLSPPDMSFPASLAAQHFLLEEEKRAKELEKLLNTHIDELQRHTEFTLNKYSKLKQNRHI
What is the function of this protein?
Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells.  Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles.  Probably sufficient for the specification and formation of the deuterosome inner core.  Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis (By similarity).
What are the official names of this protein?
Deuterosome assembly protein 1, Coiled-coil domain-containing protein 67.
What is the protein family that this protein belongs to?
Belongs to the CEP63 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the deuterosome.
Protein: RL10_METMP
Sequence: MIEAKSEHKIAPWKIEEVNALKELLKSSNIIALIDMMEVPAVQLQEIRDKIRDQMTLKMSRNTLMKRAIEEVAEETGNPEFAKLVDYMDKGAAIIATEMNPFKLYKTLDESKSPAPVKGGAIAPCDIEVKAGSTGMPPGPFLSELKAVGIPAAIDKGKIGIKEDKIVVKEGEVVSQKLAVVLSALDIKPVTVGLNVLGVYEDGVIYTESDLKIDEEEFVGKIQKAYTSAFNLSVNAVIPTSATVETIVQKAFNDAKAVSVESAFVTDKTADAILGKAYAQMIAVAGLAGDDALDEDLKGKISSGAAAPVEEAPVEEKKEEKKEEAAAPAGLGMLF
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10, Acidic ribosomal protein P0 homolog.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: MIC10_ARATH
Sequence: METTKSNSSESDVNAKWDACLDLTARRFVYSSLGGAFAGLLFFRSPVTRWASIAFGAGIGIGSAYTDCSRVFDASSSTSATLLAAPKSTETSVSQAAEE
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
What are the official names of this protein?
MICOS complex subunit MIC10, AtMic10.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic10 family.
Protein: ARGE_MORAB
Sequence: MQLPQFSELYKSLILIPSISSLEKELDISNKPVIDLLSGWFSELGFSINITSVPETNGKFNLVATYGQGDGGLLLAGHTDTVPFDDDLWTKDPFKLTEKDDKWYGLGTIDMKGFFAFVLEACKNIDLTKLDKPLRILATADEETTMAGARAIAAAQSFRPDYAVIGEPTGMVPVFMHKGHMSEAIRITGRSGHSSDPANGINAIEIMHQVTGQLLQLQRKLKEQYACDHFVIPQPTLNFGHVHGGDSPNRICGSCELHIDMRPIPGVNPDELFMLLNQALLPIIKQWPGAVDVYHLHEPIPAYACNTDSALIKLAEKLTGEAVIPVNYCTEAPFIQQLGCDTIVMGPGSINQAHQPDEYLDLSAIKPTQAIIQKLIEETCKN
What is the function of this protein?
Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids.  Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
What are the official names of this protein?
Acetylornithine deacetylase, AO, Acetylornithinase, N-acetylornithinase, NAO.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. ArgE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAPK5_MOUSE
Sequence: MSEDSDMEKAIKETSILEEYSINWTQKLGAGISGPVRVCVKKSTQERFALKILLDRPKARNEVRLHMMCATHPNIVQIIEVFANSVQFPHESSPRARLLIVMEMMEGGELFHRISQHRHFTEKQASQVTKQIALALQHCHLLNIAHRDLKPENLLFKDNSLDAPVKLCDFGFAKVDQGDLMTPQFTPYYVAPQVLEAQRRHQKEKSGIIPTSPTPYTYNKSCDLWSLGVIIYVMLCGYPPFYSKHHSRTIPKDMRKKIMTGSFEFPEEEWSQISEMAKDVVRKLLKVKPEERLTIEGVLDHPWLNSTEALDNVLPSAQLMMDKAVVAGIQQAHAEQLANMRIQDLKVSLKPLHSVNNPILRKRKLLGTKPKDGIYIHDHENGTEDSNVALEKLRDVIAQCILPQAGKGENEDEKLNEVMQEAWKYNRECKLLRDALQSFSWNGRGFTDKVDRLKLAEVVKQVIEEQTLPHEPQ
What is the function of this protein?
Tumor suppressor serine/threonine-protein kinase involved in mTORC1 signaling and post-transcriptional regulation.  Phosphorylates FOXO3, ERK3/MAPK6, ERK4/MAPK4, HSP27/HSPB1, p53/TP53 and RHEB.  Acts as a tumor suppressor by mediating Ras-induced senescence and phosphorylating p53/TP53.  Involved in post-transcriptional regulation of MYC by mediating phosphorylation of FOXO3: phosphorylation of FOXO3 leads to promote nuclear localization of FOXO3, enabling expression of miR-34b and miR-34c, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent MYC translation.  Acts as a negative regulator of mTORC1 signaling by mediating phosphorylation and inhibition of RHEB.  Part of the atypical MAPK signaling via its interaction with ERK3/MAPK6 or ERK4/MAPK4: the precise role of the complex formed with ERK3/MAPK6 or ERK4/MAPK4 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPK (ERK3/MAPK6 or ERK4/MAPK4), ERK3/MAPK6 (or ERK4/MAPK4) is phosphorylated and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6 (or ERK4/MAPK4).  Mediates phosphorylation of HSP27/HSPB1 in response to PKA/PRKACA stimulation, inducing F-actin rearrangement.
What are the official names of this protein?
MAP kinase-activated protein kinase 5, MAPK-activated protein kinase 5, MAPKAP kinase 5, MAPKAPK-5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to the cytoplasm following phosphorylation and activation. Interaction with ERK3/MAPK6 or ERK4/MAPK4 and phosphorylation at Thr-182, activates the protein kinase activity, followed by translocation to the cytoplasm. Phosphorylation by PKA/PRKACA at Ser-115 also induces nuclear export.
Protein: RL35_SALTI
Sequence: MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHLRPKAMVSKGDLGLVIACLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: CCMA_PASMU
Sequence: MSMSYQLKTKKLACQRGDNVLFTDFNFVWNSGDFVQIEGHNGIGKTSLLRILIGLAQQREGEVFWNGIPIQTQRETFQYDLLYLGHHSGIKPELTAWENLKFYQQMSACELGEDKLWQVLETVGLLGREDIPAAQLSAGQQRRIALARLWLSKAPLWILDEPFTAIDKHGVQVLTTLFEQHATQGGIVIFTSHQDVQSRLLKKVRLENYKFTE
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CA11B_CONAH
Sequence: MGMRMMFTLFLLVVLTTTVVSFPSDSASDGRDDEAKDERSDMYKSKRNGRCCHPACGKHFSCGR
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.
What are the official names of this protein?
Alpha-conotoxin-like Ac1.1b.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LG3BP_PONAB
Sequence: MTPPRLFWVWLLVAGTQGVNDGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGSGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTNETRSTHTLDLSRELSEALGQIFDSQRGCDLSISVNVQGEDALGFCGHTVILTANLEAQALWKEPGSNVTMSVDAECVPMVRDLLRYFYSRRIDITLSSVKCFHKLASAYGARQLQGYCATLFAILLPQDPSFHMPLDLYAYAVATGDALLEKLCLQFLAWNFEALTQAEAWPSVPTDLLQLLLPRSDLAVPSELALLKAVDTWWGERASHEEVEGLVEKIRFPMMLPEELFELQFNLSLYWSHEALFQKKTLQALEFHTVPFQLLARYKGLNLTEDTYKPRIYTSPTWSAFVTDSSWSARKSQLVYQSRRGPLVKYSSDYFQAPSDYRYYPYQSFQTPQHPSFLFQDKRVSWSLVYLPTIQSCWNYGFSCSSDELPVLGLTKSGGSDRTIAYENKALMLCEGLFVADVTDFEGWKAAIPSALDTNSSKSTSSFPCPAGHFNGFRTVIRPFYLTNSSGVD
What is the function of this protein?
Promotes integrin-mediated cell adhesion.  May stimulate host defense against viruses and tumor cells (By similarity).
What are the official names of this protein?
Galectin-3-binding protein, Lectin galactoside-binding soluble 3-binding protein.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space, extracellular matrix.
Protein: MIAA_XANC8
Sequence: MAADQRPLAIAVMGPTASGKTALAIEAAQRWGGEIVSVDSALVYRGLDIGAAKPDAAMRAAVPHHLLDLRDPWQVYSAAEFAADARTAMAQIVARGKIPILAGGTGLYFRAALEGLAQMPEADPAVRLAIAAEAEQVGWGALHAQLARIDPVAAARIHATDRQRIQRALEVYRISGKPISYWQTRPAGPRAPVRVLKLVLAPRQRAVLHARIAMRLDVMLADGFLTEVEQLRALPQMRAVAAPLDLPAVRAVGYRQAWEYLDGAGSLAEFRDKAVQATRQLAKRQLTWLRGELDARWFDPERDRGQLEQAVAGFLGQRRTMQQPSAV
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: BCHL_CHLP8
Sequence: MSLVLAVYGKGGIGKSTTSANISAALALKGAKVLQIGCDPKHDSTFPITGKLQKTVIEALEEVDFHHEELSPEDIVETGFAGIDGLEAGGPPAGSGCGGYVVGESVTLLQEMGLYDKYDVILFDVLGDVVCGGFSAPLNYADYAVIIATNDFDSIFAANRLCMAIQQKSVRYKVQLAGIVANRVDYTKGGGTNMLDQFAEQVGTRLLAKVPYHELIRKSRFAGKTLFAMDENEPELADCLAPYNEIAEQILSKTPIASVPKPIGDREIFDIVGGWQ
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: MATRX_LPMV
Sequence: MAMHAKIPLNQPQNQDTAQLQPFPLVMSEPENGKRRLLKQLRIKRIPPLSIGDQQITFINTYGFIRANRTFTEFISELHRPGLQPIVTACMLPFGAGPLLDSPEKILEGLDLCEIKVRKSAAVKEEILFEVTALPKIFQGFQISAQPLIKVSSEKYVKAPGKINAGVEYKFYPTFVSLTYCPTTLKIQGRQTLATVRAKFMRSIHLEILLIFECKDDAPMAKALIKRDERDGYQASVWVHMCNITKSTQKFKTYDDSYFGQKVLAMKPVIGLVDMWGPTITVHISGKMPKTAAPYFNSRGRSCHPLSEVAPSIAKMAWSNGCRIHQVNAILQESDLSLIPGSDDILFRKVPVDPENINFKSTYWNPFRK
What is the function of this protein?
The M protein has a crucial role in virus assembly and interacts with the RNP complex as well as with the viral membrane.
What are the official names of this protein?
Matrix protein.
What is the protein family that this protein belongs to?
Belongs to the morbillivirus/respirovirus/rubulavirus M protein family.
What are the subcellular locations of this protein?
Virion.
Protein: RL9_METCA
Sequence: MDVILLEKVPNLGSLGDKVSVRPGYGRNFLIPKGKAVAATAAKLAEFEQRRAELEKKASEELAAAQARAEAVARLNVSIAQKAGEEGKLYGSVGTKDIAEAVTAAGVPVERHEVRLPHGPIRLAGDYEITLHLHSDVNATLNLKVIGE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: YALD_TRYBB
Sequence: MGPSTSPLVGCNGDRKVLQQPVKITLMEKWFPGDVAESTLDPAQAPLYQYTEGVDEANEGCPRAFVTLKAGVEEDALKYSFVGCCSNFDEVVSRMTKESWIELRNTRGQISSRASLRRKKGAVRAMKYILSTNVGEHVPKSSILRHWNEYLLILARNRDSSLPFRFSFGSKVRALPLSSLPSLAAH
What are the official names of this protein?
Uncharacterized 21 kDa protein in aldolase locus, ORFD.
Protein: H2A3_LYTPI
Sequence: AKSRSSRAGLQFPVGRVHRFLRKGNYAQRVGAGAPVYLAAVFEYLAAEILELAGNAAPDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTAKSSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A, sperm.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PG140_VACCW
Sequence: MDMMLMIGNYFSGVLIAGIILLILSCIFAFIDFSKSTSPTRTWKVLSIMAFILGIIITVGMLIYSMWGKHCAPHRVSGVIHTNHSDISMN
What is the function of this protein?
Envelope protein which is a major component of the mature virion (MV) membrane.  Essential for membrane biogenesis.  Is required, together with OPG144, to form bona fide crescents, which can progress to form the immature virion (IV) membrane.  OPG140 and OPG144 form a lattice that is stabilized by disulfide bonds and serves as an anchor within the viral membrane to which several other proteins important in virion structure and morphogenesis attach.
What are the official names of this protein?
Virion membrane protein OPG140.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG140 family.
Protein: HLDD_AROAE
Sequence: MIIVTGGAGFIGSNIVQGLNARGITDILVVDDLTDGHKCLNLADADIHDYMDKDDFLRRVEANEDFGPVEAIFHEGACSSTTEWDGRFVMAVNYEYTKSLLGWAVARKVPLLYASSASVYGMGPTFRESREFEHPLNMYAYSKFLFDCHLRRFAPGIDSQVVGLRYFNVYGPREQHKGSMASVAYHFHNQLNDSGRLRLFEGADGYGPGEQQRDFIHVDDVVAVNLWLLDNPGVRGIFNVGTGRAQSFNEVAHAALSWHKGSTAGGGIDYIAFPEHLRGRYQSYTQADITALRQAGYEGEFMPVEVGVPRYLEWLALRD
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.