PharMolix/UniProtQA huggingface dataset:
Protein: RL28_RALPJ
Sequence: MARVCQVTGKAPMVGNNVSHANNKTKRRFLPNLQNRRFWVESENRWVSLRVSNAGLRLIDKKGIDEVLVDLRARGEV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: PDXH_BARQU
Sequence: MSNKVQMDNDFMQMQKPFALFAKWLEEATVSEINDPNAMALATVDETGLPNVRMVLLKDFSSRGFVFYTNYESCKGQEILKSMKASLVFHWKSLRRQIRIRGIVEKVSTQEADVYFQSRPRGSRIGAWASKQSQPLENRFVLEKAIAQYTARYAVGNIPRPPYWSGFRVKPLSIEFWCDRPFRLHDRLLFTRDSVEQVDWQRQKLYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: TFOY_ALIF1
Sequence: MDKPVLKDSLRLLSSLGKITSRSMFGGFGIFIDDTMFALVVQDKLHLRASDETINLFKEQGFEPYVYKKRGFPVVTKYFAISPECWDEPDSILIQAVVALDVAKKDKEKQKSAGPSRIKDLPNLRLATERMLKKAGITTVEELKNTGSVNAYKAIQQTHSSSVSDELLWSLEGAIKGMHWSVISAETRNELRKQL
What is the function of this protein?
Required for efficient DNA transformation jointly with TfoX1.
What are the official names of this protein?
DNA transformation protein TfoX2.
What is the protein family that this protein belongs to?
Belongs to the TfoX family.
Protein: RNPA_OLEA2
Sequence: MLARPSRLTRRPDYVACYNTGRRYFSKHFIVFALEREGAAPVWRYGLAVSRKVGDAVRRNRTKRVLREFFRLYQDDMPGGMDLVVVPKRRLDPRRVTLDLAVQELLPLMREIRDSLCREANDGTP
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: KYNB_BURMA
Sequence: MDTIWDISPPIAPATPVWPGDTPVGIERVWRIEAGSPVNVARVTLSPHTGAHADAPLHYDADGTPIGAVPLDAYLGRCRVIHCIGARSAVTPEHVRAALAGAPPRVLLRTYGQAPQHAWDSAFCAVAPETIDLLAAHGVRLVGIDTPSLDPQESKTMDAHRRIRAHRMAILEGLVLDEIAAGDYELIALPLKFATLDASPVRAVLRALPAAPR
What is the function of this protein?
Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
What are the official names of this protein?
Kynurenine formamidase, KFA, KFase, Arylformamidase, N-formylkynurenine formamidase, FKF.
What is the protein family that this protein belongs to?
Belongs to the Cyclase 1 superfamily. KynB family.
Protein: PHS_RALPJ
Sequence: MMPTLNEDQRKALFAEVPGWTLQSERDAIQKTFTFADFNAAFGFMTRVAIKAEQMNHHPEWFNVWNRVDITLSTHDANGLTHRDADLARFIEQAAKGTGAK
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: AROQ_SHEFN
Sequence: MSQTAKVLLINGPNLNLLGRREPGHYGHQTLTTIVDELTRNATQAGVTLEHIQSNAEYQLIDAIHATDAQFIIINPAAFTHTSVALRDAILGVAIPFIEVHLSNVHAREPFRHHSYFSDKALGVICGLGAQGYDFALQAAIKHLSDKH
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: CARB1_METJA
Sequence: MESIKKVMVFGSGPIVIGQAAEFDFSGSQACKALKEEGIYTILVNSNPATIQTDTDMADKVYLEPLHPTIVEKIIEKERPDAILPTMGGQTGLNLALELHRRGILDKYGIKLLGSNIRTIEIAEDRELFAEAMAEINEPVTKCKAVNSVDEAVEFAEEIGYPVIVRPAFTLGGTGGGIAHNKEELIDITSKGLKYSIINQVLIDESVLGWKEFELEVMRDRKDTCIIVCGMENIDPMGIHTGESIVVSPIQTLPDEFYQKLRNAAIKIIRHLGIEGGCNIQFAVNKEMTEYRVIEVNPRVSRSSALASKATGYPIARIAAKIAIGKTLDEILNDVTKETPASFEPTLDYVVVKIPRWPFDKFKTVDKKLGTSMKSTGEVMAIGRSFEEALQKAIRSLDIGRFGIIGDGKDKDYTDEEIEEILKNPTDERIFVIAKALEKGWSVEKIVELTDIDEFFIKKIKNIVDMKKELEKLKEEIKKLNA
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, N-terminal section, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: EIF3F_ASPNC
Sequence: MAEADSFLHLARPLGPVAVGTAPTTAPLNVVIQPQALFSILDHSLRRNADQERVIGTLLGTRSEDGTEVEIRSTFAVGHTETTDQVEVDMEYQKQMLALHLKANPKEVLVGWYATSSELNTFSALIQNFYSGQGDGTWPHPAVHLTVSTEAGKDIETRAYISAPVGVTAERAADSAAFIPVPYEIRYGEAEKSGLEAIGAARDAEERRANIFTDIEALERAIEDVLGMIDRVSRYVESVIDEEAPASTALGQYLLNTLALAPKVEPADIERDFNNHIQDVLVVSYLANTIRTQMELSNRLATAQLTLGGESGSGESGDKRGGQRGGKGGRGGQQRTQERSGEEARAPYPFLCQPRRTRSYEERTNEAQNGKEEKK
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit F, eIF3f.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit F family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXH_SHIFL
Sequence: MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQMLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RISB_ACTPJ
Sequence: MAKITGNLVATGLKFGIVTARFNDFINDKLLSGAIDTLVRHGADENNIDTAWVPGAFEIPLVAKKMATSGKYDAVICLGTVIRGSTTHYDYVCNEAAKGIGAVALETGVPVIFGVLTTENIEQAIERAGTKAGNKGSECALGAIEIVNVLKAI
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RBL_ANEMR
Sequence: MSPQTETKAGVGFKAGVKDYRLTYYTPEYETKETDILAAFRMTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYDIEPVAGEENQYIAYVAYPLDLFEEGSVTNLFTSIVGNVFGFKALRALRLEDLRIPPSYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFVAEAIFKSQAETGEIKGHYSNATAGTSEEMLKRAACARELGVPIIMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKASRLSGGDHIHAGTVVGKLEGEREVTSGFVDSLRDDYIERDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVASEACVQARNEGRDLAREGNEVIREASKWSPDLAAACEVWKEIKFEYETIDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid.
Protein: NUDL_SALPA
Sequence: MDTSRLTLDHFLSRFQLLRPQITHETLNQRQAAVLIPVVRRPQPGLLLTQRAIHLRKHAGQVAFPGGAVDSTDASLIAAALREAQEEVAIPPQAVEVIGVLPPVDSVTGFQVTPVVGIIPPNLPWRASEDEVSAVFEMPLAQALQLGRYHPLDVYRRGNSHRVWLSWYEHYFVWGMTANILRELALQIGVKP
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Uncharacterized Nudix hydrolase NudL.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.
Protein: INVO_CANLF
Sequence: MSQQHTLPVTLPPALSQGPLKPESPPIDTQQEQVKQPTSLPVLCQKMPSSLPGKVPLGHGEKHTSLVKGEPEQQCEPQEQEQQQKQQESQEQKLHLEQCLEQHQEQQESQDQKLYPEQCLEQQQEQQESQDQKLYPEQCLEQQQEQQESQEKELHLEQEQQKEELQQQEQQQGKEQCEKHQEAKNLEQQLEQIGAQRKQQQKEQLEQEKKLVDQHLDQEPAQRTEQPEKKEEQVLEQQGQQEGQLEQPAFVPAQVQVREPLKGEVLPLIEQQHQKQEVHDPPEHQ
What is the function of this protein?
Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.
What are the official names of this protein?
Involucrin.
What is the protein family that this protein belongs to?
Belongs to the involucrin family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Constituent of the scaffolding of the cornified envelope.
Protein: RUVA_EHRCJ
Sequence: MIGSLTGIIEEIYITYIILNVGNVGYIVHVSQRVLQTCKIGNNIKLYIETHVNRDNLTQLYGFLDKQEQDYMRMLITINGINYKTAMSILSKLSPEQIFSAVVSNNKNAFRGNGIGEKLAGRITTELQYKISKMPIEETLIIKEDDSLAALISLGYDKLKAFNAIQEIKSDFPNANIQEIIRKALQKLSQ
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: PURQ_GEOTN
Sequence: MKFAVIVFPGSNCDVDMYHAIADELGEEVEYVWHDEENLDRFDAILLPGGFSYGDYLRSGAIARFSKVMAAVKQAAEAGKPVLGVCNGFQILLEAGLLPGAMRRNQGLKFICRPVQLVVENNETMFTSAYGKDEVITIPIAHGEGNYYCDEQTLNRLVENRQIVFRYHGENPNGSLADIAGIVNERGNVLGMMPHPERAVDALLGSADGLKLFRSIVNYWRETHVVTA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLO_BREBN
Sequence: MGDYMIRATGFNGHVRAFAARTTESVEDMRRRHDMWNTATAAAGRTLTITLMMGAMLKGNESLHVKVKGGGPIGQIMAEANAHGEGIAYVSNPHVHFELNDKGKLDVARAVGTDGFVYVTKDLGLKEPYQGSAPIVSGEIGEDFTYYFVMSEQTPSAVGVGVLVNPEDRSVLAAGGFILQLLPNTPEEVVAAIEERLGQLPQVSRMIGEGLTPEEILDRVLDEPKILSHTEIQFSCKCSADKVVQALISMGREEMEGLIEEQGEAEVHCHFCNERYHYDRSALEDILKDM
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_COXB1
Sequence: MAKKRYRKVTEGIAHIKATFNNTMISVSDSQGNVLCFRSAGGSGFKGSRKGTPYGAQMASEEVGRLARDNFDMRRIAVRVKGPGAGRDSAIRGLRSAGLEVIHLEDRTPLPHNGCRPRKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: CAPSD_LDCPR
Sequence: MHSTTNNSNKRNNEEKHKQPEANGSADNGEGASGTRNQTAGDTTPEAGTRNETEAGAGARGQTDGASRSGTNAKVATASSARQMDMEKAAETTSTIENVNDVGIMQQKKPPTVIQSRTDVFNEQFANEALHPTTKVIFNGLDVNTEVQPLSDDFEQISDPKGYLTYSVKYEDQFAKKDKLRASEADDRIVGPTVNLFKYGSAVVNIDLNQDFFDTTTGINLTKGILLVQDLLVPIGVTAGAEQSSEYVSGLLMVLFKVMTDNRLVIVGETTTPISNTLSTVVNNILRTTYHNNVGINPALLRDFTHVNWLNQDITNMLQQAGTRFGLGLTATRLDYVRLVKTIVGYALDIDHFAASVLNINLRALMEANVTADDRIKALQAHSMISTQFHGPNQGALRPELAFDHDHVIRCLMLAAANYPRLEGIIVQINTGYVASTNVIRPVSEKRYFPENLEQNQSAARLVSAVKARASEADISSIHLAIAREVSPMFNVHELKKIAESFEDPSSIVVVLEFILFSLFFPTEFNRIKGDIQNVLLLFFSRWYPVEYGIFIQRGATYTINAAGEFEFSGRNEKWDQSSYLSEHFPALFSDVPLAGANTIIAIMRLFTPQGFLRTDDLAIAANFPRASRNPQTYIPYTNQRGTVTNEFASRFRTIVATLANVVNERAVQDDMQKATRSCTKQWLRHLETQFDNIAVAHTDHLSVVYATMSNFMLNFTNNFSGNHATFKPEQYVITSPEGSYKPIMERQGETVDGLTIIDTSIVWPILCQCTYPLVRQSGKGVDAVSIMEEIVYPDPGTTLSQSLSVAQILSKLTLPDAFINMILSGGDSVAMRTYQTEANDELDEGIRMTTYDQYLSHIRERLHITNVPDPIYITGASTPDQIAASVQATHVAVVLYQNGVINGPASTYLRENEVLVVMPDYSNVAARFVYANAQMNNNRYHESVLEIADIFDQADFIQTDNAVRRLRALMPTLSTSQIRHAIERIAQITNVDSTDYGKLTLRFLGTLTRPLKMQNAQIRRIRPDGTVLRYDDQIDIEAFRWSRYFLDELQLRRLAVGLRLIANPRIARRFNGVRIMYLTDDDPDPDFVPAIPEGYVAVQYAHRLFSSSLANKRNRVTYTHPPTGMAYPSPTGRPHVHLTINERAGMSKLVADNIIASVIKSNWVVDILDIEYTAEVMTPSEGYTQHVDAESIMTAPKGKLFHLQFMDGLLRPEPSAFDPPASGEDIRLIYPLQPISVARSMRAIVNHNEVDRPRGAVAPSSYEMDTGTLSRNGDLLYSPVENGQAGIPKLEVDHISFSNVVSMMTSNIRTGDDMAVERVNPSDIRAINIRNA
What is the function of this protein?
Capsid protein self-assembles to form an icosahedral capsid with a pseudo T=2 symmetry, about 50 nm in diameter, and consisting of 120 capsid proteins.  The capsid encapsulates the genomic RNA (By similarity).
What are the official names of this protein?
Major capsid protein VP1.
What are the subcellular locations of this protein?
Virion.
Protein: Y690_METJA
Sequence: MKLMDVHVLFSGGKDSSLSAVILKKLGYNPHLITINFGVIPSYKLAEETAKILGFKHKVITLDRKIVEKAADMIIEHKYPGPAIQYVHKTVLEILADEYSILADGTRRDDRVPKLSYSEIQSLEMRKNIQYITPLMGFGYKTLRHLASEFFILEEIKSGTKLSSDYEAEIRHILKERGESPEKYFPEHKQTRVVGLKKEI
What are the official names of this protein?
Uncharacterized protein MJ0690.
Protein: DNAA_NOSS1
Sequence: MMEMPIDNLWSQVLERLQIELSRPTFETWIKTANAERLENNCLVIITPNPFARNWLQKYYISTIANVVQSILGHPVEIYITVAKGEEFEEIGGGGEWELPTTNIINETPNQNRQPNTELNAKYVFSRFVVGANNRMAHAASLAVAESPGREFNPLFLCGGVGLGKTHLMQAIGHYRWEICPNSKIFYVSTEQFTNDLITAIRNDSMQSFREHYRAADVLLVDDIQFIEGKEYTQEEFFHTFNTLHEAGKQVVIASDRPPNQIPSLQERLCSRFSMGLIADIQAPDLETRMAILQKKSEYEKIRLPRDVIEYIATNFTSNIRELEGALTRALAYISIWGLPMTVANLAPVLVTPMEKIEATPEAILTVIADNFDISIEDLKSNSRRREISWARQIGMYLMRQHTDLSFPRIGEEFGGKDHTTVLYSCDKIAQLVESDRGLSQTLRQLSDRIKMNSRSRKP
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAK5_ASHGO
Sequence: MSPTNNGRNKKLGPRRKVPGRVSKSKSRAKVQAGDAKRVLDANALKWEKVDVPDTLGDFGGFYGLEEIDGVDVEVVDGKVQFVARDESRLKSPADAVDGTDMVEVDEDAGMEDVTEFRNLDDVAEGELSALSDEGSASEDDGSDSSGSSDMDEDDDQELQSEIFNKDIGLDEAEAPELPSWTNTMKLSATVLQGLSRLGFSNPTEIQLQSIPKALDGHDIMGKASTGSGKTLAYGIPILEGIIRDDTDSRPIGLIFTPTRELAHQVTDHLREVGALLVKRNPYSIMCLTGGLSIQKQERLLKYKGSARVVVATPGRFLELLEKDQTLIDRFAKVDTLVLDEADRLLQDGHFEEFERILKHLSRARKFTNGKKHGWKTMIYSATFSLDYFNKLSNTSWKKMKKAPSENEMEEVLKHLMTKIPFRGKPLIIDTNPEQKVASQIKESLIECLPTERDLYVYYFVTLYPGTTLVFCNAIDSVKKLNAYLHNLKISAFQIHSSMLQKNRLKSLEKFQEQAKKNQALNKPTVLIASDVAARGLDIPGIQHVIHYHLPRSADVYIHRSGRTARAENEGVAVTICSPQEAMGPLRKLRRVLAGKAGSKGKRWQNEIALLPVEPDIVSQLRERSRLASALADSEIATSSLSKDDNWLKKAADDLGIDVDSDDETKDTFLAKNKTKKLNKQLDKSTSKSYKMELNALLNTPIRKDARKSYLTGGLSNLADDLTKKKGHSSIIGHDKVDALTLLKSKSKRAKR
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase MAK5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX24/MAK5 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: G3P_BPI22
Sequence: MKRKIIAISLFLYIPLSNADNWESITKSYYTGFAMSKTVESKDQDGKTVRKEVITQADLTTACNDAKASAQDVFNQMKLTFSGIWPDSQFRLVTGDTCVYNGSPSEKTESWSIRAQVEGDMQRSVPDEEPSEQTPEEICEAKPPIDGVFNNVSKGDEGGFYINYNGCEYEATGVTVCQNDGTVCASSAWKPTGYVPESGESSSSPVKDGDTGGTGEGGSDTGGDTGGGDTGGGSTGGDTGGSTGGGSTGGGSTGGSTGKSLTKEDVTAAIHDASPSIGDAVKDSLTEDNDQNDNQKKADEQSAKASASVSDAISDGMRGVGNFVDDLGGESSQYGIGNSEMDLSVSLAKGQLGIDLEGHGSAWESFLNDGALRPSIPSGHGCTDFVMFQGSVYQLDIGCDKLGDIKSVLSWVMYCLTFWYVFQSATSLLRKGEQ
What is the function of this protein?
Plays essential roles both in the penetration of the viral genome into the bacterial host via pilus retraction and in the extrusion process.  During the initial step of infection, G3P mediates adsorption of the phage to its primary receptor, the tip of host I-pilus.  Subsequent interaction with the host entry receptor tolA induces penetration of the viral DNA into the host cytoplasm.  In the extrusion process, G3P mediates the release of the membrane-anchored virion from the cell via its C-terminal domain (By similarity).
What are the official names of this protein?
Attachment protein G3P, Gene 3 protein, G3P, Minor coat protein.
What is the protein family that this protein belongs to?
Belongs to the inovirus G3P protein family.
What are the subcellular locations of this protein?
Virion. Host membrane; Single-pass type I membrane protein. Note=Prior to assembly, G3P is found associated with the bacterial host inner membrane. There are about five copies of this protein per mature phage that are located on the head side of the filamentous virion.
Protein: VGLU3_RAT
Sequence: MPFNAFDTFKEKILKPGKEGVKNAVGDSLGILQRKLDGTNEEGDAIELSEEGRPVQTSRARAPVCDCSCCGIPKRYIIAVMSGLGFCISFGIRCNLGVAIVEMVNNSTVYVDGKPEIQTAQFNWDPETVGLIHGSFFWGYIVTQIPGGFISNKFAANRVFGAAIFLTSTLNMFIPSAARVHYGCVMCVRILQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGVLVQYIGWASVFYIYGMFGIIWYMFWLLQAYECPAVHPTISNEERTYIETSIGEGANLASLSKFNTPWRRFFTSLPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFAISKVGLLSAVPHMVMTIVVPIGGQLADYLRSRKILTTTAVRKIMNCGGFGMEATLLLVVGFSHTKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKHKTREEWQNVFLIAALVHYSGVIFYGVFASGEKQDWADPENLSEEKCGIIDQDELAEETELNHEAFVSPRKKMSYGATTQNCEVQKTDRRQQRESAFEGEEPLSYQNEEDFSETS
What is the function of this protein?
Multifunctional transporter that transports L-glutamate as well as multiple ions such as chloride, sodium and phosphate (PubMed:12097496, PubMed:12388773, PubMed:27133463).  At the synaptic vesicle membrane, mainly functions as an uniporter that mediates the uptake of L-glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells (PubMed:12097496, PubMed:12388773, PubMed:27133463).  The L-glutamate uniporter activity is electrogenic and is driven by the proton electrochemical gradient, mainly by the electrical gradient established by the vacuolar H(+)-ATPase across the synaptic vesicle membrane (PubMed:12388773, PubMed:12097496).  In addition, functions as a chloride channel that allows a chloride permeation through the synaptic vesicle membrane that affects the proton electrochemical gradient and promotes synaptic vesicles acidification (PubMed:27133463).  At the plasma membrane, following exocytosis, functions as a symporter of Na(+) and phosphate from the extracellular space to the cytoplasm allowing synaptic phosphate homeostasis regulation (By similarity).  The symporter activity is electrogenic (By similarity).  Moreover, operates synergistically with SLC18A3/VACHT under a constant H(+) gradient, thereby allowing striatal vesicular acetylcholine uptake (PubMed:18278042).
What are the official names of this protein?
Vesicular glutamate transporter 3, VGluT3, Solute carrier family 17 member 8.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cell membrane; Multi-pass membrane protein. Synapse, synaptosome.
Protein: EX53_MYCPU
Sequence: MTKSGSKSEKFLLIDGNYLVHRSYYVSFKFKNNFRSTIYLFFQTIIKIIKNLNPENIFIAFDEEGGTWRHDLCKEYKSQRSKMEDEFWNIFKAIREILDSINLNSGGFRGHEADDVIATITSKFKDENQIYIFSRDKDLLQLIDKNVYITHDNELKNLISIENFYQNFQLEPDQIVDFKAIAGDSSDNLKGIAGIGEKGAKNLLNNFKSLEKIFDSLESTNLISKAQKQKIRDGKEQALFLKKIVTLNKEVPMKLEKELFAIKININEEILEKLDKYDSRYVLKQFEKALESDDYLW
What is the function of this protein?
5'-3' exonuclease acting preferentially on double-stranded DNA.
What are the official names of this protein?
5'-3' exonuclease.
Protein: KITH_HHV23
Sequence: MASHAGQQHAPAFGQAARASGPTDGRAASRPSHRQGASEARGDPELPTLLRVYIDGPHGVGKTTTSAQLMEALGPRDNIVYVPEPMTYWQVLGASETLTNIYNTQHRLDRGEISAGEAAVVMTSAQITMSTPYAATDAVLAPHIGGEAVGPQAPPPALTLVFDRHPIASLLCYPAARYLMGSMTPQAVLAFVALMPPTAPGTNLVLGVLPEAEHADRLARRQRPGERLDLAMLSAIRRVYDLLANTVRYLQRGGRWREDWGRLTGVAAATPRPDPEDGAGSLPRIEDTLFALFRVPELLAPNGDLYHIFAWVLDVLADRLLPMHLFVLDYDQSPVGCRDALLRLTAGMIPTRVTTAGSIAEIRDLARTFAREVGGV
What is the function of this protein?
Catalyzes the transfer of the gamma-phospho group of ATP to thymidine to generate dTMP in the salvage pathway of pyrimidine synthesis.  The dTMP serves as a substrate for DNA polymerase during viral DNA replication.  Allows the virus to be reactivated and to grow in non-proliferative cells lacking a high concentration of phosphorylated nucleic acid precursors.
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae thymidine kinase family.
Protein: COAD_RUEPO
Sequence: MRVALYPGTFDPITLGHVDIIRRAAALVDKLVIGVAINRDKGPLFTLEERVAMIEAECAALSAETGTEIVAHPFENLLIDCARDVGAQIIVRGLRAVADFEYEFQMVGMNRALDDSVETVFLMADARRQAIASKLVKEIARLGGDVSKFVPPRVNDALKERLGRA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.