PharMolix/UniProtQA huggingface dataset:
Protein: CAPSD_SCPMV
Sequence: MSGLFHHRTKPREIRAFVMATRLTKKQLAQAIQNTLPNPPRRKRRAKRRAAQVPKPTQAGVSMAPIAQGTMVKLRPPMLRSSMDVTILSHCELSTELAVTVTIVVTSELVMPFTVGTWLRGVAQNWSKYAWVAIRYTYLPSCPTTTSGAIHMGFQYDMADTLPVSVNQLSNLKGYVTGPVWEGQSGLCFVNNTKCPDTSRAITIALDTNEVSEKRYPFKTATDYATAVGVNANIGNILVPARLVTAMEGGSSKTAVNTGRLYASYTIRLIEPIAAALNL
What are the official names of this protein?
Capsid protein, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the icosahedral plant coat protein family.
What are the subcellular locations of this protein?
Virion.
Protein: NUSB_ECOLC
Sequence: MKPAARRRARECAVQALYSWQLSQNDIADVEYQFLAEQDVKDVDVLYFRELLAGVATNTAYLDGLMKPYLSRLLEELGQVEKAVLRIALYELSKRSDVPYKVAINEAIELAKSFGAEDSHKFVNGVLDKAAPVIRPNKK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: LRP12_HUMAN
Sequence: MACRWSTKESPRWRSALLLLFLAGVYGNGALAEHSENVHISGVSTACGETPEQIRAPSGIITSPGWPSEYPAKINCSWFIRANPGEIITISFQDFDIQGSRRCNLDWLTIETYKNIESYRACGSTIPPPYISSQDHIWIRFHSDDNISRKGFRLAYFSGKSEEPNCACDQFRCGNGKCIPEAWKCNNMDECGDSSDEEICAKEANPPTAAAFQPCAYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDCDVPTCGQWLKYFYGTFNSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGYGDYVKIYDGLEENPHKLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDETNCTMCQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCPVIVPTRVITAAVIGSLICGLLLVIALGCTCKLYSLRMFERRSFETQLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQASVLENLRLAVRSQLGFTSVRLPMAGRSSNIWNRIFNFARSRHSGSLALVSADGDEVVPSQSTSREPERNHTHRSLFSVESDDTDTENERRDMAGASGGVAAPLPQKVPPTTAVEATVGACASSSTQSTRGGHADNGRDVTSVEPPSVSPARHQLTSALSRMTQGLRWVRFTLGRSSSLSQNQSPLRQLDNGVSGREDDDDVEMLIPISDGSSDFDVNDCSRPLLDLASDQGQGLRQPYNATNPGVRPSNRDGPCERCGIVHTAQIPDTCLEVTLKNETSDDEALLLC
What is the function of this protein?
Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction.  May act as a tumor suppressor.
What are the official names of this protein?
Low-density lipoprotein receptor-related protein 12, LDLR-related protein 12, LRP-12, Suppressor of tumorigenicity 7 protein.
What is the protein family that this protein belongs to?
Belongs to the LDLR family.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein. Membrane, coated pit.
Protein: UNG_MYCBP
Sequence: MTARPLSELVERGWAAALEPVADQVAHMGQFLRAEIAAGRRYLPAGSNVLRAFTFPFDNVRVLIVGQDPYPTPGHAVGLSFSVAPDVRPWPRSLANIFDEYTADLGYPLPSNGDLTPWAQRGVLLLNRVLTVRPSNPASHRGKGWEAVTECAIRALAARAAPLVAILWGRDASTLKPMLAAGNCVAIESPHPSPLSASRGFFGSRPFSRANELLVGMGAEPIDWRLP
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPR_SIVEK
Sequence: MEQAPEDQGPQREPYNEWALELLEDLKNEALRHFPRPWLHGLGQYFYNTYGDTWEGVEAIIRTLQQLLFIHYRIGCQHSRIGITPQRRRNGASRS
What is the function of this protein?
During virus entry, plays a role in the transport of the viral pre-integration (PIC) complex to the host nucleus.  This function is crucial for viral infection of non-dividing macrophages.  May act directly at the nuclear pore complex, by binding nucleoporins phenylalanine-glycine (FG)-repeat regions.
What are the official names of this protein?
Protein Vpr, R ORF protein, Viral protein R.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPR protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host extracellular space. Note=Incorporation into virion is dependent on p6 GAG sequences. Lacks a canonical nuclear localization signal, thus import into nucleus may function independently of the human importin pathway. Detected in high quantity in the serum and cerebrospinal fluid of AIDS patient.
Protein: DPO4_CORGB
Sequence: MQRWVLHIDMDAFFASCEQLTRPTLRGRPVLVGGVSGRGVVAGASYEARKFGARSAMPMHQAKARVGFGAVVVTPRHIVYSAASRRVFQIVEKRAGIVERLSIDEGFMEPEALVGATPEEVKQWAEELRAEIKEVTGLPSSVGAGSGKQIAKIGSGEAKPDGVFVVPVDKQHDLLDPLPVGALWGVGPVTGSKLASMGVETIGDLAALTQKEVEISLGATIGISLWNLARGIDDRPVEPRAEAKQISQEHTYEKDLLTRQQVDAAIIRSAEGAHRRLLKDGRGARTVSVKLRMADFRIESRSYTLSYATDDYATLEATAFRLARYPGEVGPIRLVGVSFSGLEESRQDILFPELDQQIIVPPAPDTDYEVGVQSSSSSESTQVEAPQDVALSMWRATQDVYHPEYGHGWVQGAGHGVVSVRFETRSTTKGRTKSFSMDDPDLTPADPLDSLDWADWFAENGETGDDE
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTCC_LENHI
Sequence: MTKDFRQNVFQGRSVLAEKDFSAAELEYLIDFGLHLKALKKAGIPHHYLEGKNIALLFEKSSTRTRSAFTTASIDLGAHPEYLGQNDIQLGKKESTSDTAKVLGSMFDGIEFRGFKQSDAEILARDSGVPVWNGLTDEWHPTQMLADFMTVKENFGKLQGLTLTFMGDGRNNVANSLLVTGAILGVNIHIVAPKALFPTEETQNIAKGFAEKSGAKLVITDDLDEGLKGSNVVYTDVWVSMGESNWEERVKELTPYQVNMEAMKKTGTPDDQLIFMHCLPAFHNTDTQYGKEIKEKYGITEMEVTDEVFTSKYARQFEEAENRMHSIKAMMAATLGNLFIPRV
What is the function of this protein?
Involved in the catabolism of arginine.  Catalyzes the phosphorolysis of citrulline, the reverse reaction of the biosynthetic one, yielding ornithine and carbamoyl phosphate which serve to generate ATP from ADP.
What are the official names of this protein?
Ornithine carbamoyltransferase, catabolic, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHJ_PAUCH
Sequence: MIEPSIIPVLVENTEEKTFKFQPGQVSQWLTGQGLQHQILEPDLLGVELIGVEPSELQKIAEALKSNGFDYLQCQGGYDEGPGGRLVSFYHLIKLGTIADHYLTPNTLPPNSILKEVRLKVFLLRDGNLSVPSLYSIFRGSDWQERETFDMFGISYEGHPHPKRLLMPEDWKGYPLRKDYIQPDFYEMQVAY
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, organellar chromatophore, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, organellar chromatophore thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: SC23B_HUMAN
Sequence: MATYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPLACLLTPLKERPDLPPVQYEPVLCSRPTCKAVLNPLCQVDYRAKLWACNFCFQRNQFPPAYGGISEVNQPAELMPQFSTIEYVIQRGAQSPLIFLYVVDTCLEEDDLQALKESLQMSLSLLPPDALVGLITFGRMVQVHELSCEGISKSYVFRGTKDLTAKQIQDMLGLTKPAMPMQQARPAQPQEHPFASSRFLQPVHKIDMNLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQGPGMVVGDELKIPIRSWHDIEKDNARFMKKATKHYEMLANRTAANGHCIDIYACALDQTGLLEMKCCANLTGGYMVMGDSFNTSLFKQTFQRIFTKDFNGDFRMAFGATLDVKTSRELKIAGAIGPCVSLNVKGPCVSENELGVGGTSQWKICGLDPTSTLGIYFEVVNQHNTPIPQGGRGAIQFVTHYQHSSTQRRIRVTTIARNWADVQSQLRHIEAAFDQEAAAVLMARLGVFRAESEEGPDVLRWLDRQLIRLCQKFGQYNKEDPTSFRLSDSFSLYPQFMFHLRRSPFLQVFNNSPDESSYYRHHFARQDLTQSLIMIQPILYSYSFHGPPEPVLLDSSSILADRILLMDTFFQIVIYLGETIAQWRKAGYQDMPEYENFKHLLQAPLDDAQEILQARFPMPRYINTEHGGSQARFLLSKVNPSQTHNNLYAWGQETGAPILTDDVSLQVFMDHLKKLAVSSAC
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex.
What are the official names of this protein?
Protein transport protein Sec23B, hSec23B, SEC23-related protein B.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC23 subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol.
Protein: TDH_PARP8
Sequence: MKALAKLERAPGLTLTRVKKPEVGHNDVMIRITRTAICGTDIHIWKWDDWAQKTIPVPMHVGHEYVGEIVEMGQEVRGFSIGDRVSGEGHITCGFCRNCRAGRRHLCRNTVGVGVNREGAFAEYLVIPAFNAFKIPPEISDDLAAIFDPFGNATHTALSFNLVGEDVLITGAGPIGIMAVAIAKHVGARNVVITDVNDYRLELARKMGATRAVNVSRETLRDVMRDLHMTEGFDVGLEMSGVPSAFTSMLEAMNHGGKIALLGIPPAQTAIDWTQVIFKGLEIKGIYGREMFETWYKMVAMLQSGLDLSPILTHRFAVDDYEKAFATMLSGESGKVILDWTV
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_SYNP1
Sequence: MPNLKAIRDRIKTIKDTRKITEAMRLVAAAKVRRAQEQVMASRPFADRLAQVLYGLQTRLRFEDANLPLLAKRPVKTVALLVVTGDRGLCGGYNTNVIRRAKERTEELEAEGIKYTLVIVGRKAAQYFQRRDYPIDAVYSGLEQIPSASEAGQIANELLSLFLSETVDRVELIYTKFVSLISSKPVVQTLLPLDPQGLEAADDEIFRLTTRASHLEVNREKVTSNLPALPPDMIFEQDPVQILDALLPLYLSNQLLRALQEAAASELAARMTAMNNASDNAQTLIGTLTLSYNKARQAAITQEILEVVAGAEALR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: BPS2_ACIAM
Sequence: MKVRVYNIGGIVSPLEVELTKGVNIYKAPNAYGKTSLAKALVSLLTSAIKPDDLLNVFANSGYVELDLDGRTYYRRIKRVKNKIMESSKLLLDDDRALLLSYFSPENKLLNQIMSGEENVEWFISATSKINELKSKKEEMETKLHNLQAEIDDLNRKHKEAIELQTKIKQIEDEIARLEKEKESDKVLNKTTQTISITNENKLRDIKEKIEVKKRELEDLQNRIARLDQEIKNKESLASPEIRQSYERQLQEINAQLQKITAQRNEAEIEIRLLEKVLDQIRESEKQHLTTCYVCGSHVDPSIWKVRIDVISKELQEKNSLYAGIKKEADELLSKKSEIEKKLKELDQISSEISKLKMSRSELENRIESVKSTIDDLERQRREMEERFNRNAEIYRVYDINDSINKRIEELKKKKDEYEYELAINGIPSTILNKISEKQKELQEVQKMVDDLEKEYMRRLTIAREEFVKIANYLLKELEFDLRAEIDENDRLVVKRNDATLELRKLSSSERTTLALILVLTALKSYFKTPFFIVDESFMTFDQRRFDKIVKYLNSITDYVIITKSDENIELLKETMEPLASS
What are the official names of this protein?
Protein bps2.
Protein: Y3317_KLEP7
Sequence: MNLQHHFLIAMPALQDPIFRRSVVYICEYNDEGAMGIIINKPLENLQVEGILEKLKIVPEPRNPEIRLDKPVMLGGPLAEDRGFILHTPPSDFSSSIRISDNTVITTSRDVLETLGTDRQPGNVLVALGYSSWEKGQLEQEILDNAWLTAPADQNILFRTPIADRWREAAKLIGIDIVTMPGVAGHA
What are the official names of this protein?
UPF0301 protein KPN78578_33170.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: GCSPA_DESHD
Sequence: MNYVPNTVDQQEQILTRIGVGSLEELFADIPESVRRQAQLKIREGLSELELVKYMGRLAAENKTVEEYTSYLGAGAYEHFIPSYVDQLLLRSEFYTAYTPYQPEISQGTLQAIYEFQTLVCELTGMDGANASMYDGASALAEAALMSCDATRRKKVLVPQTIHPEYREVLRTYLLPRGVEILEIPYQEGAVDSEALEKALNTEVAAVLIQSPNFFGMIEKAVEIGQMAHAKGGLLVMAVNPVSLGLLKSPGELGADIVVGEGQPFGNPLNFGGPYLGFLACREKYVRRMPGRIVGATKDKNGKKGYVLTLQAREQHIRREKAASNICSNEALCALAFTIHLSGLGKRGLKEMARLNLQKAHYGAEEIGKLPGMSLAFQGPFFHEFVIKTEVSPRKINEALLSHKIIGGLELSRFYPELDQHLLFCVTETKTKEDIDRLVAGMGEIK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: TATA_MYCBP
Sequence: MGSLSPWHWAILAVVVIVLFGAKKLPDAARSLGKSLRIFKSEVRELQNENKAEASIETPTPVQSQRVDPSAASGQDSTEARPA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: YIDC_PSEPW
Sequence: MDIKRTILIAALAIVSYVMVLKWNDDYGQAALPTQNTAASTVAPGLPDGVPAANNGASADVPSANAESSPAELAPVALSKDLIRVKTDVLELAIDPVGGDIVQLNLPKYPRRQDHPDIPFQLFDNGGERVYLAQSGLTGANGPDARSTGRPLYAAEQKSFQLADGQEQLVVDLKFSDNGVNYIKRFSFKRGEYDLSVSYLIDNQSGQAWSGNMFAQLKRDASGDPSSSTATGTATYLGAALWTAGEPYKKVSMKDIDKGSLKENVSGGWVAWLQHYFVTAWIPAKSDNNVVQTRKDSQGNYIIGYTGPAISVPAGGKAETSAMLYAGPKIQSKLKELSPGLELTVDYGFLWFIAQPIFWLLQHIHSLLGNWGWSIIVLTMLIKGLFFPLSAASYRSMARMRAVAPKLAALKERFGDDRQKMSQAMMELYKKEKINPLGGCLPILVQMPVFLALYWVLLESVEMRQAPWMLWITDLSIKDPFFILPIIMGATMFIQQRLNPTPPDPMQAKVMKMMPIIFTFFFLWFPAGLVLYWVVNNCLSISQQWYITRRIEAATKKAAA
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUOK_BACC1
Sequence: MSSVPASAYLTLAIILFCIGLFGALTKRNTVIVLVCIELMLNAANLNLVAFSKLGLFPNLTGQIFSLFTMAVAAAEAAVGLAILIALYRNRTTVHVDEMDTLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LPT_SHIBS
Sequence: MKRISTTITTTITITTGNGAG
What is the function of this protein?
This protein is involved in control of the biosynthesis of threonine.
What are the official names of this protein?
thr operon leader peptide, thr operon attenuator.
What is the protein family that this protein belongs to?
Belongs to the thr operon leader peptide family.
Protein: SPEE_ECO55
Sequence: MAEKKQWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVESITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFKLVIDDGVNFVNQTSQTFDVIISDCTDPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGFYQAAIPTYYGGIMTFAWATDNDALRHLSTEIIQARFLASGLKCRYYNPAIHTAAFALPQYLQDALASQPS
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACSA_HELP2
Sequence: MQLDEDLEFAKKIFNPNRAFAKQARIKNMCEYKDLVHEANEDYEHFWGELAKQKLTWFKPFDKVLNSDNAPFFKWFENGKINVSYNCIDRHLKDKKNKVAIIFEGEMGDYNVITYRKLHSEVNKTANLLKNEFNVKKGDRVIIYMPMIVESVYMMLACARIGAIHSIVFAGFSPEALRDRINDAQAKLVITADGTFRKGKPYMLKPALDKALENNACPSVEKALIVIRNAREIDYVRGRDFVYNEMVNYQSDKCEPEMMDSEDPLFLLYTSGSTGKPKGVQHSSAGYLLWAQMTMEWVFDIRDNDNFWCTADIGWITGHTYVVYGPLACGATTLILEGTMSYPDYGRWWRMIEEYRVDKFYTSPTAIRMLHAKGENEPLKYNLESLKVLGTVGEPINPTAWKWFYEKIGNSKCSIVDTWWQTETGGHIISPLPGATPIRASCATLPLPGIHAEVLNEDGTKTKPGEQGFLCITKPWPSMVRNIWGDEKRYIDSYFSQIKLNGEYVYLSGDGAIVDENGYITIIGRTDDIVNVSGHRIGTAEVESAISKHEMVVECAVVGIPDTIKGEGLFAFVVLCDGAKCNLGESLELLKEMNHILSVEIGKIAKLDNVMYVPGLPKTRSGKIMRRLLKSIAKKEPITQDLSTLEDVNVVKEIMSIVQMEE
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: SYFB_NITWN
Sequence: MKFTLSWLKDHLDTDEPLEKLADKLTMIGLEVEHIADKSKTFAPFTIARVVSAVQHPNADRLRVCMVDTGETSDKGDPSYIQVVCGAPNAREGLISVFAPPGTHIPGKNITLGVGTIRGVESRGMLCSAAELEISDDHDGIIELPADAPVGAGYAEWAGLGDPVIEINLTPNRQDCTGVHGIARDLSAADMGRFKDPTIKPVTGEFPCPVKVTVEDASLCPGFALRMVRGVKNGPSPEWLQKRLTSIGLRPINALVDITNFMTYDRARPLHVFDAKKVHGDLTIRRARDGETLKALDGRIYTLDPNVCVIADDKGVESLAGIMGGEETGCDETTTDVLIESALWSEINIAQTGRRLGINSDARYRFERGVDPAFMVPGLEMATRLVMELCGGSPSENVVAGQALPEDRVIDFPLSEIKRLAAIDVPLVEVRRILGHLGFMVAGSGPVVKVAIPTWRTDVQGKADLVEEIVRIVGVDKVPMTPFDRGEAPRKPVLTSIQSRTRKARRALAARGMVEAVNWSFISRTQAELFGGGSSELALANPIASDLSDMRPSLLPGLVAIAQANADRGFADVALFEVGQIFRGDGPQDQFMAAAGLRRGIASSAGLGRHWSGSATANALDAKADAFAVLAAAGAPAAALQIATSHESKNFPAWLHPGRSAAIQIGPHNVLGYFGELHPRVLDELKAEGPLLGFEVILDRIPEAKQKPTRAKPVLELPAFQPVSRDFAFIVDRTVKAADIVRAAQNVDRKLVSGVTVFDIYEGKGIDADKKSVAIAVRLQPRDRTFTDQEIEAVAGKIVAEVAKRTGGSLRG
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GDL17_ARATH
Sequence: MGILRFVLLISLNLVLFGFKTTVSQPQQQAQVPCLFIFGDSLVDNGNNNRLLSLARANYRPYGIDFPQGTTGRFTNGRTYVDALAQILGFRNYIPPYSRIRGQAILRGANFASGAAGIRDETGDNLGAHTSMNQQVELYTTAVQQMLRYFRGDTNELQRYLSRCIFYSGMGSNDYLNNYFMPDFYSTSTNYNDKTFAESLIKNYTQQLTRLYQFGARKVIVTGVGQIGCIPYQLARYNNRNNSTGRCNEKINNAIVVFNTQVKKLVDRLNKGQLKGAKFVYLDSYKSTYDLAVNGAAYGFEVVDKGCCGVGRNNGQITCLPLQTPCPDRTKYLFWDAFHPTETANILLAKSNFYSRAYTYPINIQELANL
What are the official names of this protein?
GDSL esterase/lipase At1g33811, Extracellular lipase At1g33811.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMA_HELHP
Sequence: MNCEHFGICGGCTNIQDYSTQLQAKHNLTLQEFQSFLDTKSKNFQYPTNPLAIEVFASPQEGFRARAEFRFSHVFQNKSGLDFAMNAFGYNHRVPIKKCPILLPTLQDIMPLLLHYLNTYDLLNHKLYACNLLSSLQNEIIITLIYHKSLDSHWESLALKIQKELEYTLNTNIHIIGRSKNHKHILSNDIICEHLTLFANTPKERTYTFFKQESRFCQPNPFINTQMLEFIVSALSSIYTPQTPCDMLELYCGSGNFTIPLASIFRHIFATEVVKSAITLLQKNMAKNNIENIIPARLNAFESIQALRKERVFFRLKNIDLDAFAFDCVLIDPPRSGVGEEEVLYFLQNFNTIIYVSCNPHTLLNDLRILSQSHYVMRFGLFDQFPHTYHRECIVILRKSNKIL
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: CAH1_HUMAN
Sequence: MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHNNRPTQPLKGRTVRASF
What is the function of this protein?
Catalyzes the reversible hydration of carbon dioxide (PubMed:10550681, PubMed:18618712).  Can hydrate cyanamide to urea (PubMed:10550681).
What are the official names of this protein?
Carbonic anhydrase 1, Carbonate dehydratase I, Carbonic anhydrase B, CAB, Carbonic anhydrase I, CA-I, Cyanamide hydratase CA1.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2BL1_MOUSE
Sequence: MAKPTFKRQCYIKRHLRPLYRKHSRCSSINLGHGNYSLYINRVLKEVVPNRGISSYSVDIMNILINDIFERIATEACQQMFLRKRCTLTPGDIQQAVHLLLPKKLATLAVTFGSKAVHRFIHS
What is the function of this protein?
May act as an acrosome-nuclear docking protein in sperm.
What are the official names of this protein?
Histone H2B variant L1, Histone H2B subacrosomal variant.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Subacrosomal region. Does not localize in nucleus (By similarity).
Protein: DTD_SYNFM
Sequence: MRAVVQRVAEASVTVNGEETGRIGKGVLVFLGVGPDDGSGDIRYLSEKIVNLRIFPDASDKMNLSVREVGGGVLVISQFTLFGDCRKGRRPSYAGAAPPELARRLYGEFVEELKKQAVPVATGMFQEMMRVHLVNDGPVTLLLDSRKVF
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.