PharMolix/UniProtQA huggingface dataset:
Protein: Y1492_METVS
Sequence: MQFRKGRPKILRLISEEPKFNIFKPVGIPKNELESVVLTLEELESLRLVDYVGQSHEDAADSMGISRRVFWNILKSARKKVSDALINGKMIDIGGGYYQIRKCNEQECQGMPCRFGLSNCFKNKNKDNEL
What are the official names of this protein?
UPF0251 protein Mevan_1492.
What is the protein family that this protein belongs to?
Belongs to the UPF0251 family.
Protein: GCST_YERPY
Sequence: MAKQTPLYDQHVACGARMVDFHGWMMPLHYGSQIDEHHFVRQDAGMFDVSHMTIVDLHGNRTREFLRYLLANDVAKLTQPGKALYTGMLNESGGVIDDLIVYFLSEDYFRLVVNSATRDKDLAWISQHAEPYQVEVTVRDDLALIAVQGPQAQQKVATLLTTEQQQAIAGMKPFFGIQTGDLFIATTGYTGEAGYEIALPKQQVVAFWQQLLAAGVKPAGLGARDTLRLEAGMNLYGQEMDEKTSPLAANMGWTVAWQPEDRQFIGRAALERQRMKGTEQLVGLIMTEKGVLRNELPVYFFDAAGNQHVGVITSGSFSPTLGFSIALARVPTGIGEHAVVQIRNREMPVRVTKPGFVRAGKAIVL
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: MSRB_ECOLU
Sequence: MANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVYHCLICDAPLFHSQTKYDSGCGWPSFYEPVSEESIRYIKDLSHGMQRIEIRCGNCDAHLGHVFPDGPQPTGERYCVNSASLRFTDGENGEEING
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: ILVC_XANC5
Sequence: MSNDTQPKIAIIGYGSQGRAHALNLRDSGFDVTVGLRAGGPTEAKAQADGFIVVAPSEAVKSADLVAILTPDMVQKKLYEEVIAPNMKQGACLLFAHGLNVHFDMIKPRADLDVVLVAPKGPGALVRREYEIGRGVPCIYAVYQDTSGKAEQFALTYAGGLGGARANIIKTTFKEETETDLFGEQAVLCGGASSLVQAGFEVLVEAGYQPEIAYYEVLHELKLIVDLFYEGGITRMLEFVSETAQYGDYVSGPRVIDAGTKARMKDVLTDIQNGTFTKNWVAEYDAGLPNYNKFKQADLEHPIEEVGKKLRAKMVWLNGQQQAAAAPANQQAA
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: ACDD2_METTE
Sequence: MAKKMKLSEITNMFAGMNVEALEGVTIEGDIEIDLGGLGGFDPMLAAALGQESAVLAQHFARIAGMFGYPVSVGAPAAAPAAVSPALAAPKLKDLIPAKFEFSNIEEWTTQVEEVPIGNTSADGGSRGKRILLGGEKALPFFPDAPMPNRNQVTIDVFDMRLGLAKAVKENYDDVMDNPGEWAKKNVEKFNADMITIHLISTDPLIKDTSPKDAAKTVEEVLQAVDVPIAIGGSGNPQKDPLVLAKAAEVAEGERCLLASASLNLDYAAIAEAALKYDHDVLSWTQLDMNAQKELNRKLMKQCNVPRDRIIMDPTTAALGYGLDYAYTNMERIRLAALMGDDELTFPMSSGTTNAWGARESWMVSSPLKEDSDWGPREYRGPIWEIITGLSLAIAGNDLFMMMHPTSVAVLKHMTQTLFGSIEAEPVDIANWIGAEV
What is the function of this protein?
Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy.  Probably maintains the overall quaternary structure of the ACDS complex (By similarity).
What are the official names of this protein?
Acetyl-CoA decarbonylase/synthase complex subunit delta 2, ACDS complex subunit delta 2, Corrinoid/iron-sulfur component small subunit 2.
What is the protein family that this protein belongs to?
Belongs to the CdhD family.
Protein: FUT8_PONAB
Sequence: MRPWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDRPDHSSRELSKILAKLERLKQQNEDLRRMAESLRIPEGPIDQGPAIGRVRVLEEQLVKAKEQIENYKKQTRNGLGKDHEILRRRIENGAKELWFFLQSELKKLKNLEGNELQRHADEFLLDLGHHERSIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSKAKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPVSETCTDRSGISTGHWSGEVKDKNVQVVELPIVDSLHPRPPYLPLAVPEDLADRLVRVHGDPAVWWVSQFVKYLIRPQPWLEKEIEEATRKLGFKHPVIGVHVRRTDKVGTEAAFHPIEEYMVHVEEHFQLLARRMQVDKKRVYLATDDPSLLKEAKTKYPNYFISDNSISWSAGLHNRYTENSLRGVILDIHFLSQADFLVCTFSSQVCRVAYEIMQTLHPDASANFHSLDDIYYFGGQNAHNQIAIYAHQPRTADEIPMEPGDIIGVAGNHWDGYSKGVNRKLGRTGLYPSYKVREKIETVKYPTYPEAEK
What is the function of this protein?
Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
What are the official names of this protein?
Alpha-(1,6)-fucosyltransferase, Fucosyltransferase 8, GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase, alpha1-6FucT, GDP-fucose--glycoprotein fucosyltransferase, Glycoprotein 6-alpha-L-fucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 23 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: RL29_CLOK5
Sequence: MKARELQELRQGSSPQDLQEKVQDLKSELFNLRFQLATGQLENPMRIREVKKSIAQIKTILREKELRAFEQ
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: ENV_SFVCP
Sequence: MAPPMTLQQWIIWNKMNKAHEALQNSTTVTDQQKEQIILEIQNEEVRPTRKDKIRYLLYTCCATSSRVLAWMLLVCVLLIVVLVSCFLTISRIQWNRDIQVLGPVIDWNVTQRAVYQPLQTRRIARSLRMQHPVPKYIEVNMTSIPQGVYYEPHPEPIVVTERVLGLSQVLMINSENIANNANLTQEVKKLLAEVVNEEMQSLSDVMIDFEIPLGDPRDQEQYIHRKCYQEFAHCYLVKYKTPKSWPTEGLIADQCPLPGYHAGLSYKPQSIWDYYIKVEITRPANWSSQAVYGQARLGSFYVPKGIRQNNYSHVLFCSDQLYSKWYNIENSIEQNEKFLLNKLDNLTTGSSLLKKRALPKEWSSQGKNALFKEINVLDVCSKPELVILLNTSYYSFSLWEGDCNFTKNMISQLVPECEGFYNNSKWMHMHPYACRFWRSKNEKEETKCRPGEKEKCLYYPYQDSLESTYDFGFLAYQKNFPAPICIEQQEIRDKDYEVYSLYQECKLASKVHGIDTVLFSLKNFLNHTGRPVNEMPNARAFVGLVDPKFPPSYPNVTREHYTSCNNRKRRSTDNNYAKLKSMGYALTGAVQTLSQISDINDENLQQGIYLLRDHVITLMEATLHDISVMEGMFAVQHLHTHLNHLKTMLLERRIDWTYMSSAWLQQQLQKSDDEMKVIKRIAKSLVYYVKQTYNSPTATAWEIGLYYELTIPKHVYLNNWNVVNIGHLVQSAGQLTHVTIAHPYEIINKECTETKYLHLKDCRRQDYVICDVVEIVQPCGNSTDTSDCPVWAEAVKEPFVQVNPLKNGSYLVLASSTDCQIPPYVPSIVTVNETTSCYGLNFKKPLVAEERLGFEPRLPNLQLRLPHLVGIIAKIKGLKIEVTSSGESIKDQIERAKAELLRLDIHEGDTPAWIQQLAAATKDVWPAAASALQGIGNFLSGAAHGIFGTAFSLLGYLKPILIGVGVILLIILIFKIVSWIPTKKKSQ
What is the function of this protein?
The leader peptide is a component of released, infectious virions and is required for particle budding.
What are the official names of this protein?
Envelope glycoprotein gp130, Env polyprotein.
What are the subcellular locations of this protein?
[Envelope glycoprotein gp130]: Host endoplasmic reticulum membrane. Note=The polyprotein has a highly unusual biosynthesis for a retroviral glycoprotein. It is translated as a full-length precursor protein into the rough endoplasmic reticulum and initially has a type III protein configuration with both its N and C-termini located intracytoplasmically (By similarity). SUBCELLULAR LOCATION: [Leader peptide]: Virion membrane; Single-pass type II membrane protein. Host endoplasmic reticulum membrane; Single-pass type II membrane protein. Note=Its N-terminus is located inside the viral particle. SUBCELLULAR LOCATION: [Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host endoplasmic reticulum membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host endoplasmic reticulum membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM.
Protein: NCAP_NDVAF
Sequence: MSSVFDEYEQLLAAQTRPNGAHGGGERGSTLRVEVPVFTLNSDDPEDRWNFAVFCLRIAVSEDANKPLRQGALISLLCSHSQVMRNHVALAGKQNEATLTVLEIDGFTSSVPQFNNRSGVSEERAQRFMVIAGSLPRACSNGTPFVTAGVEDDAPEDITDTLERILSIQAQVWVTVAKAMTAYETADESETRRINKYMQQGRVQKKYILHPVCRSAIQLTIRHSLAVRIFLVSELKRGRNTAGGSSTYYNLVGDVDSYIRNTGLTAFFLTLKYGINTKTSALALSSLTGDIQKMKQLMRLYRMKGENAPYMTLLGDSDQMSFAPAEYAQLYSFAMGMASVLDKGTGKYQFARDFMSTSFWRLGVEYAQAQGSSINEDMAAELKLTPAARRGLAAAAQRVSEETGSVDIPTQQAGVLTGLSDGGPRASQGGSNKSQGQPDAGDGETQFLDLMRAVANSMREAPNSAQSTTHPEPPPTPGPSQDNDTDWGY
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The nucleocapsid (NC) has a helical structure.  The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.  During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NP, Protein N.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses nucleocapsid family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: GCSP_SALAR
Sequence: MTQTLSQLENSGAFIERHIGPDAGQQQEMLNAVSAESLNALIGQIVPKDIQLANPPQVGEAATEYAALAELKAIVGRNKRFTSYIGMGYTAVQLPPVILRNMLENPGWYTAYTPYQPEVSQGRLEALLNFQQVTLDLTGLDMASASLLDEATAAAEAMAMAKRVSKLKNANRFFVASDVHPQTLDVVRTRAKTFGFDVIVDDAAKALDHQNVFGVLLQQVGSTGEIHDYSALISKLKARKVIVSVAADFMALVLLTAPGKQGADIVFGSAQRFGVPMGYGGPHAAFFAAIDEFKRSMPGRIIGVSKDAAGNAALRMAMQTREQHIRREKANSNICTSQVLLANIASLYAVYHGPVGLKRIAQRIHRLTDILAAGLQQKGLKLRHAHYFDTLCVEVADKAAVLARAEAAEINLRSDIHNAVGITLDETTTRDNVLQLFTILLGDDHGLNIETLDKDVALDSRSIQQSMLRDDAVLTHPVFNRYHSETEMMRYMHSLERKDLALNQAMIPLGSCTMKLNAAAEMIPITWPEFAELHPFCPPEQAEGYQQMISQLSDWLVKLTGYDAVCMQPNSGAQGEYAGLLAIRHYHESRNEGHRDICLIPASAHGTNPASAHMAGMQVVVVACDKNGNIDLADLRAKAELHANNLSCIMVTYPSTHGVYEETIRDVCDIVHQFGGQVYLDGANMNAQVGITSPGFIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVVQIEGMLTRQGAVSAAPFGSASILPISWMYIRMMGAEGLKQASQVAILNANYIASRLKDAYPILYTGRDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAGTLMVEPTESEGKAELDRFINAMLAIRAEIERVKAGEWPLEDNPLVNAPHTQNELAAEWNHSYSREVAVFPAGVANKYWPTVKRLDDVYGDRNLFCSCVPMSEYQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: PUR7_CYAP4
Sequence: MHTDEKIYEGKAKVLYPTDDPQVFQVHFKDDATAFNAQKRGAIAGKGRINCTISAHLFQMLAKAGIANHFLSQPAPDQMLVRAVQIIPVEVVVRNIAAGSLCQQTGLPLGTPLKKPLVEFYYKNDDLGDPLLTRERLLLLELATAAEIEQLEALARQINEHLIVFFQQCGITLVDFKLEFGRDQNQHILLADEISPDTCRLWNQSETDPEQRVMDKDRFRRDLGNVESAYEQVMARVLAQPL
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: TAIL_BPMR1
Sequence: MAQDKYIVALQIADKDLAKKLTIEEATLLGSLAEGGHTISNDLAEIIQGGKKDYSRNSVEEEIKLTLDVVPGDKGQLALKESVKQFKQLRVWIWETKKRDGKHHGVFAYVVIEEHEWSFDDEDNKIEITAKVKFNSADGTINDLPKEWLNPSALAPVVEFEDMNAYEDSYENRTKKTTAGSSDLSM
What are the official names of this protein?
Putative tail protein, Putative uncharacterized protein orf50.
Protein: TRI6_TRIAR
Sequence: MNDDSETPGAEAWMALPLFNRKASPDHEQNVLTWFECWRPPEDDVSDFKSLEDYEDSPTHSIGSSGLHSGSLDSDYHYYTASDLVFSDDGGVGRNADLLSEISDDHIPQLSFSTPSTCPFPGCKSTALFTTGRDFRRHYRQHFKRFFCRYEECSQSTNDPGDAGKKGFATRKDRARHEAKHNPAIRCQWRDNNGDQCTRTFSRMDNMRDHFRRIHGKE
What is the function of this protein?
Transcriptional activator of part of the trichothecene biosynthesis cluster that mediates the production of the antimicrobial trichothecene harzianum A (HA) that plays a role in Botrytis cinerea antagonistic activity and plant defense priming (PubMed:21642405, PubMed:30121242).  Regulates expression of both trichothecene and mevalonate pathway genes (PubMed:30121242).
What are the official names of this protein?
Trichothecene biosynthesis transcription regulator TRI6, Trichothecene biosynthesis protein 6.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNS2B_HUMAN
Sequence: MKQKMMARLLRTSFALLFLGLFGVLGAATISCRNEEGKAVDWFTFYKLPKRQNKESGETGLEYLYLDSTTRSWRKSEQLMNDTKSVLGRTLQQLYEAYASKSNNTAYLIYNDGVPKPVNYSRKYGHTKGLLLWNRVQGFWLIHSIPQFPPIPEEGYDYPPTGRRNGQSGICITFKYNQYEAIDSQLLVCNPNVYSCSIPATFHQELIHMPQLCTRASSSEIPGRLLTTLQSAQGQKFLHFAKSDSFLDDIFAAWMAQRLKTHLLTETWQRKRQELPSNCSLPYHVYNIKAIKLSRHSYFSSYQDHAKWCISQKGTKNRWTCIGDLNRSPHQAFRSGGFICTQNWQIYQAFQGLVLYYESCK
What is the function of this protein?
Hydrolyzes DNA under acidic conditions.  Does not require divalent cations for activity.  Participates in the degradation of nuclear DNA during lens cell differentiation.
What are the official names of this protein?
Deoxyribonuclease-2-beta, DNase II-like acid DNase, DNase2-like acid DNase, Deoxyribonuclease II beta, DNase II beta, Endonuclease DLAD.
What is the protein family that this protein belongs to?
Belongs to the DNase II family.
What are the subcellular locations of this protein?
Lysosome.
Protein: T2A1_THAGE
Sequence: MRLDLDFGRGLVAHVMLDNVSEEQYQQISDYFVPLVNKPKLKSRDAIGQAFVMATEVCPDANPSDLWHHVLYRIYIREKIGTDPSQSWVRTSGEAFEVALVERYNPVLARHGIRLTALFKGQKGLALTRMGVADRVGSRKVDVMIEKQGGGRSPDAEGFGVVGGIHAKVSLAERVSDDIPASRIMMGEGLLSVLSTLDVKSFPPPHGDLVNRGELGTPDRPSDKRNYIEGHGDFSACFSYNLRTSPSNATTPSGRHIYVSGFSGQDDEFTDYLVAQLA
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-ACCGGT-3' and cleaves after A-1.
What are the official names of this protein?
Type II restriction enzyme AgeI, R.AgeI, Endonuclease AgeI, Type-2 restriction enzyme AgeI.
What is the protein family that this protein belongs to?
Belongs to the BsaWI type II restriction endonuclease family.
Protein: RIMP_VARPS
Sequence: MALQQTVEQTVAGLGYDLVEIERSAGGLLRVTIDLPWTAPTSEAVAAGIPEPFVTVEDCEKVTRQLQFALEVDGVDYKRLEVSSPGIDRPLRNEQDFERFVGEVIDITLKAPMGAAAAGQVSATRKKFRGTLERVAGADGAPGWQIVWSDAPEPKPGQKVSKKRAPAKLHALGFVLDELRDARLAPIVDFKGRKAKTQPGFSDIDDGTNVPD
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VIT3_CHICK
Sequence: MRGFILALVLALVGAQKHDLEPVFSTGKTYLYDYKGLILHGLPGKGLAAAGLKLTCRLEISRVSRSDHLLQIENVFKVANKTRHHKKWIHSRVKAAVTDLWEEPSATPLSSSSSTDSSAEGEEPGNKRDKDEIWQFGKKYGADSSSSSSSSSTGSGSSKTCSSSREDSSRDKHCSVDSEYFNQQADLPIYQFWFKPADEQDPRRKVQNSSISSSSSSSSDEGISTPVSQPMFLGDSKPPVLAAVLRAIRRNEQPTGYQLVLYTDRQASRLRVQVFVSSITESDRWKLCADASVVNSHKASGTLKWGKDCQDYQVATQIATGQFAAHPAIQVKLEWSEVPSSVRKTAR
What is the function of this protein?
Phosvitin is believed to be of importance in sequestering calcium, iron and other cations for the developing embryo.
What are the official names of this protein?
Vitellogenin-3, Minor vitellogenin, VYGIII, Vitellogenin III.
Protein: TRHO_XANCP
Sequence: MITNTAAYQFAPIHDPQQLADSVLERAQQRALKGSVLVAEEGINLFLAGDAEQIASFYAWLHADARFAQMRVKYSHSAEQPFARLKVKVKPEIISFRRDDASPLQGRAPSVAPAVLRKWMQQGHDDHGRPLVLLDTRNAQEVAYGTFQGALTLPIDKFTELPEALQPHRAALADATVVSFCTGGIRCEKAALWMHAEGMDNVLQLEGGILGYFEDVGGEGYDGRCFVFDERVALDAELRPLVDGAACADAGKI
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: CDGT2_NIACI
Sequence: MKKFLKSTAALALGLSLTFGLFSPAQAAPDTSVSNKQNFSTDVIYQIFTDRFSDGNPANNPTGAAFDGTCTNLRLYCGGDWQGIINKINDGYLTGMGVTAIWISQPVENIYSIINYSGVNNTAYHGYWARDFKKTNPAYGTIADFQNLIAAAHAKNIKVIIDFAPNHTSPASSDQPSFAENGRLYDNGTLLGGYTNDTQNLFHHNGGTDFSTTENGIYKNLYDLADLNHNNSTVDVYLKDAIKMWLDLGIDGIRMDAVKHMPFGWQKSFMAAVNNYKPVFTFGEWFLGVNEVSPENHKFANESGMSLLDFRFAQKVRQVFRDNTDNMYGLKAMLEGSAADYAQVDDQVTFIDNHDMERFHASNANRRKLEQALAFTLTSRGVPAIYYGTEQYMSGGTDPDNRARIPSFSTSTTAYQVIQKLAPLRKCNPAIAYGSTQERWINNDVLIYERKFGSNVAVVAVNRNLNAPASISGLVTSLPQGSYNDVLGGLLNGNTLSVGSGGAASNFTLAAGGTAVWQYTAATATPTIGHVGPMMAKPGVTITIDGRGFGSSKGTVYFGTTAVSGADITSWEDTQIKVKIPAVAGGNYNIKVANAAGTASNVYDNFEVLSGDQVSVRFVVNNATTALGQNVYLTGSVSELGNWDPAKAIGPMYNQVVYQYPNWYYDVSVPAGKTIEFKFLKKQGSTVTWEGGSNHTFTAPSSGTATINVNWQP
What are the official names of this protein?
Cyclomaltodextrin glucanotransferase, Cyclodextrin-glycosyltransferase, CGTase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRHO_STAHJ
Sequence: MDYRVLLYYKYTTIDDPETFAAEHLEFCKSNNLKGRILVSTEGINGTLSGTKEDTDKYIEHMHSDERFADMTFKIDEAEGHAFKKMHVRPRNEIVALGLEDDVDPRVTTGKYYSPSEFKEALEDEDTVILDARNDYEFDLGHFRGAIRPDITRFRDLPDWIRENKDQLDGKNIVTYCTGGIRCEKFSGWLVKEGFENVGQLHGGIATYGKDPETKGQYWDGKMYVFDERISVDVNQVEKTVIGKEHFDGTPCERYINCSNPECNKQILVSEENEDKYLGACSYDCAKHERNRYVAKNNISDEEWNRRLENFKDVPEHAHA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: CCAR1_HUMAN
Sequence: MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPANYQLTQTAALQQQAAAAAAALQQQYSQPQQALYSVQQQLQQPQQTLLTQPAVALPTSLSLSTPQPTAQITVSYPTPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQSQTQPLLKTPPAVLQPIAPQTTFGVQTQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKAGLLQPPVRIVSQPQPARRLDPPSRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYTVQFSKFSLDCPSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESLEKNMAILDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQELRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKSLSGELREVKKDLSQLQENLKISENMNLQFENQMNKTIRNLSTVMDEIHTVLKKDNVKNEDKDQKSKENGASV
What is the function of this protein?
Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter.  Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone.  Also functions as a p53 coactivator.  May thus play an important role in transcriptional regulation (By similarity).  May be involved in apoptosis signaling in the presence of the reinoid CD437.  Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A.  Plays a role in cell cycle progression and/or cell proliferation (PubMed:12816952).  In association with CALCOCO1 enhances GATA1- and MED1-mediated transcriptional activation from the gamma-globin promoter during erythroid differentiation of K562 erythroleukemia cells (PubMed:24245781).  Can act as a both a coactivator and corepressor of AR-mediated transcription.  Contributes to chromatin looping and AR transcription complex assembly by stabilizing AR-GATA2 association on chromatin and facilitating MED1 and RNA polymerase II recruitment to AR-binding sites.  May play an important role in the growth and tumorigenesis of prostate cancer cells (PubMed:23887938).
What are the official names of this protein?
Cell division cycle and apoptosis regulator protein 1, Cell cycle and apoptosis regulatory protein 1, CARP-1, Death inducer with SAP domain.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region.
Protein: ISCS_ACIBY
Sequence: MKRPIYLDYAATTPVDPQVAERMMECLTFDGTFGNAASRSHAYGWQAEEKVEYAREQVANLIKADPREIVWTSGATESDNLALKGVAQFYASKGKHIITSKIEHKAVLDPCRELEEQGFEITYLEPEPQTGLITPEMVKAALRPDTILVSLMMVNNEIGTVTDVAAIGELTRANKTFFHVDAAQAAGKVDIDLSTMKIDLMSFSAHKIYGPKGIGALYVRRSPRVRLKAQIHGGGHERGMRSGTLATHQIVGMGEAFELAGKTMHAEQERIRKLRDKLWNGLQDLEQVFLNGHPTQNVANYLNVSFNFVEGESLMMSLKDAAVSSGSACTSATLEPSYVLRALGLSDELAHSSIRFSFGKYTTEEDIDHVLTITKAAVEKLRELSPLWDMYKEGIDLSTVEWAEH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_CHLTA
Sequence: MVKNQAQKKGVKRKQVKNIPSGIVHVKATFNNTIVTITDPAGNVISWASAGKVGYSGSRKSSAFAATVAAQDAAKAAMSSGLKEVEVGLKGTGAGRESAVRALISSGLIVSVIRDETPVPHNGCRPRKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: NMT_CAEEL
Sequence: MSHGHSHDGAPCGGHHGDDGAGGSRPSVNDVQALVDQLRLAGVDVSNMPNIPTAPRDMDEARSKSFQFWSTQPVPQMDETVPADVNCAIEENIALDKVRAEPFSLPAGFRWSNVDLSDEEQLNELYNLLTRNYVEDDDSMFRFDYSADFLKWALQVPGFRPEWHCGVRADSNNRLLAFIGAVPQTVRVYDKTVNMVEINFLCVHKNLRSRRVAPVLIREITRRVNVTGIFQAAFTAGIVIPKPVSVCRYYHRSLNPRKLIDVRFSHLSAKMTMARTIKLYKLPEETATRNLREMKSTDVPQVFKLLTTSLKQYSLAPVYNSEEELAHALVPKKGVVYSYVAENQNGKITDFVSFYSLPSTVMGHTTHKTIYAAYLYYYVAGSVTPKQLINDSLILANREKFDVFNALDLMHNEKIFSDLKFGKGDGNLQYYLYNWKCADMKPSQIGLVLQ
What is the function of this protein?
Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
What are the official names of this protein?
Probable glycylpeptide N-tetradecanoyltransferase, Myristoyl-CoA:protein N-myristoyltransferase, NMT, Peptide N-myristoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NMT family.
What are the subcellular locations of this protein?
Cytoplasm.