PharMolix/UniProtQA huggingface dataset:
Protein: UBP30_MOUSE
Sequence: MLSSRAQAARTAADKALQRFLRTGAAVRYKVMKNWGVIGGIAAALAAGIYVIWGPITERKKRRKGLVPGLVNLGNTCFMNSLLQGLSACPAFVKWLEEFTTQYSRDQQGPHTHQCLSLTLLNLLKALSCQEVTEDEVLDASCLLDVLRMYRWQISSFEEQDAHELFHVITSSLEDERDRQPRVTHLFDVHSLEQQSEMAPRQVTCHTRGSPHPTTNHWKSQHPFHGRLTSNMVCKHCEHQSPVRFDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRDVVCDNCTKIEARGTLTGEKVEHQRSTFVKQLKLGKLPQCLCIHLQRLSWSSHGTPLKRHEHVQFNEFLMMDFYKYRLLGHKPSQHGPKATENPGSAPEVQDAQAAPKPGLSQPGAPKTQIFLNGACSPSLLPALPSPVAFPLPVVPDYSSSTYLFRLMAVVVHHGDMHSGHFVTYRRSPPSAKNPLSTSNQWLWISDDTVRKASLQEVLSSSAYLLFYERVLSRVQQQGREYRSEE
What is the function of this protein?
Deubiquitinating enzyme tethered to the mitochondrial outer membrane that acts as a key inhibitor of mitophagy by counteracting the action of parkin (PRKN): hydrolyzes ubiquitin attached by parkin on target proteins, such as RHOT1/MIRO1 and TOMM20, thereby blocking parkin's ability to drive mitophagy.  Preferentially cleaves 'Lys-6'- and 'Lys-11'-linked polyubiquitin chains, 2 types of linkage that participate in mitophagic signaling.  Does not cleave efficiently polyubiquitin phosphorylated at 'Ser-65' (By similarity).  Acts as negative regulator of mitochondrial fusion by mediating deubiquitination of MFN1 and MFN2 (PubMed:24513856).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 30, Deubiquitinating enzyme 30, Ubiquitin thioesterase 30, Ubiquitin-specific-processing protease 30, Ub-specific protease 30.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: XPO7A_XENLA
Sequence: MADPVQSLAQLEILCKQLYETTDTSTRLQAEKALVEFTNSSECLSKCQLLLERGSSSYSQLLAATCLTKLVSRSTNPLPLEQRIDIRNYVLTYLATRPKLASFVTQALIQLYARITKLGWFDSQKDEYVFRSVIGDVTRFLQDSVEYCVIGVSILSQLTNEINQADATHPLTKHRKIASSFRDSALFEIFTLSCNLLKQASGKSLLLSDGSQHDLLMQLLKLTHNCLNFDFIGTSTDESSDDLCTVQIPTSWRSAFLDSSTLQLFFDLYHSIPPNFSPLVLSCLVQIASVRRSLFNNAERAKFLSHLVDGVKRILENPQSLSDPNNYHEFCRLLARLKSNYQLGELVKVENYPEVIRLIANFTVTSLQHWEFAPNSVHYLLSLWQRLAASVPYVKATEPHLLETYTPEVTKAYVTSRLESVHIILRDGLEDPLEDAGLVQQQLDQLSTIGRCEYDKTCALLVQLFDQSAQTYQELLQSGSAPSMELAVQEGRLTWLVYIIGAVIGGRVSFASTDEQDAMDGELVCRVLQLMNLTDSRLAQAGNEKLELSMLSLFEQFRKIYIGDQVQKSSKLYRRLSDVLGLNDETMVLSIFIGKIITNLKYWGRCEPITSKTLQLLNDLSIGYSSVRKLVKLSAVQFMLNNHTSEHFSFLGINSQSNLSDMRCRTTFYTALGRLLMVDLGEDEEQFSQFMMPLTAAFESLAQMFNSNNFNEQEAKRSLVGLVRDLRGIAFAFNAKSSFMMLFDWIYPAYMPILQRAIELWFHDPACTTPILKLMAELVHNRSQRLQFDVSSPNGILLFRETSKMITTYGNRILTLGELPKEQLYVLKLKGISICFSVLKAALSGNYVNFGVFRLYGDEALDNALQTFVKLLLSVPHSDLLDYPKLSQSYYSLLEVLTQDHMSFIASLEPHVIMYILSSISEGLTALDTMVCTGCCSCLDHIVTYLFKQLSRSGKKRGAPPPQESERFLHIMQQHPEMIQQMLSTVLNIIIFEDCRNQWSMSRPLLGLILLNEKYFSDLRSSIVSSQPPEKQQAMHLCFENLMEGIEGNLLTKNRDRFTQNLSAFRREVNDSMKNSSCGPNSNEMMS
What is the function of this protein?
Mediates the nuclear export of proteins (cargos) with broad substrate specificity.
What are the official names of this protein?
Exportin-7-A.
What is the protein family that this protein belongs to?
Belongs to the exportin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS16_STRA1
Sequence: MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLVAENQVTIKEERVLEWLSKGAQPSDTVRNLLSKAGVMTKFHDQKFSK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: Y1500_PASMU
Sequence: MEMTSTQRLILANQYKLMGLLDSQNAQKYQRLEAIVKGGFALELKELDKEFSDVSEQECQTVLDTLEMYNALQTSYNNLSDKSALTPHRLQFAGYCAVREKKYLNYLRFITGVEGKYQEFMRCEHGCDSQVPMWDKYMRMLDVWHACPHGYHLSMTEIQNILNA
What are the official names of this protein?
UPF0304 protein PM1500.
What is the protein family that this protein belongs to?
Belongs to the UPF0304 family.
Protein: SYGA_SALA4
Sequence: MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMTCLRALGPEPMATAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSLKELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDFLFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRIRTLTKAVAEAYYASREALGFPMCNKDK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENPL_CANLF
Sequence: MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPMEEEEAAKEEKEDSDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEDDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADEKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPSDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREAIEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIKDMLRRVKEDEDDKTVSDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETTEDTTEDTEQDDEEEMDAGTDDEEQETVKKSTAEKDEL
What is the function of this protein?
Molecular chaperone that functions in the processing and transport of secreted proteins (By similarity).  When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity).  Functions in endoplasmic reticulum associated degradation (ERAD) (By similarity).  Has ATPase activity (PubMed:17936703).  May participate in the unfolding of cytosolic leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1 to facilitate their translocation into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and secretion; the translocation process is mediated by the cargo receptor TMED10 (By similarity).
What are the official names of this protein?
Endoplasmin, 94 kDa glucose-regulated protein, GRP-94, Heat shock protein 90 kDa beta member 1.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Sarcoplasmic reticulum lumen. Melanosome.
Protein: CHZ1_ASPTN
Sequence: MGDNNRATLGSDAAANAPDAAAFDKGKGKATEDPSLEMSMDEDEESEENDDEDGGDNLEPISADNIISGGRRTRGKTIDFQEAAEKIQGDDDDEDDDEEFQPNDDDDNMRD
What is the function of this protein?
Forms a chaperone-bound H2A. Z-H2B complex that acts as a source for SWR1 complex-dependent H2A to H2A. Z histone replacement in chromatin.
What are the official names of this protein?
Histone H2A.Z-specific chaperone chz1.
What is the protein family that this protein belongs to?
Belongs to the CHZ1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DHSD_ECOLI
Sequence: MVSNASALGRNGVHDFILVRATAIVLTLYIIYMVGFFATSGELTYEVWIGFFASAFTKVFTLLALFSILIHAWIGMWQVLTDYVKPLALRLMLQLVIVVALVVYVIYGFVVVWGV
What is the function of this protein?
Membrane-anchoring subunit of succinate dehydrogenase (SDH).
What are the official names of this protein?
Succinate dehydrogenase hydrophobic membrane anchor subunit.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SKP_PHOLU
Sequence: MKKLLCAASFGIALAFSAGAQAADKIAVVNVGEIFQQLPAREAVAKQLENEFKNRASELQRMETDLQSKIQKLQRDGSTMKSSERTNLEKEVMAKREEFGKKAQAFEQDHRRREMEERNKILSRIQDAIKVVAGKEGYDIVIDANAVAYSVSGKNITASVLKQVK
What is the function of this protein?
Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm.
What are the official names of this protein?
Chaperone protein Skp.
What is the protein family that this protein belongs to?
Belongs to the Skp family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RSMH_PSEPW
Sequence: MTIDSGFNHITVLLDEAVEALALRADGCYLDGTFGRGGHSRLILSKLGPQGRLLGFDKDPQAIATGQALAAEDGRFVIVQRSFAELGAEVAERGLAGKVSGILLDLGVSSPQLDDPERGFSFLNDGPLDMRMNPDQGISAAEFIATAPVEEIARVFKEYGEERFAGRMARAVVERREKQPFTRTADLAEVLKVANPAWEKGKNPATRAFQGLRIHVNNELGDLEAGLEAALDALEVGGRLAVISFHSLEDRIVKLFMRKLVKGEADNLPRNLPVQHKVFEPKIRLIGKAQFASEAELKANPRSRSAVMRVAEKLR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_MANSM
Sequence: MATKKAGGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGSNVGMGRDHTLFATADGKVKFEVKGEKSRKYVSIVTE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: KAX2D_CENSU
Sequence: IFINVKCSSPQQCLKPCKAAFGISAGGKCINGKCKCYP
What is the function of this protein?
Selective inhibitor of voltage-gated potassium channels, blocks the Kv1. 2/KCNA2 (Kd=1. 3 nM) and Kv1. 3/KCNA3 (Kd=7. 2 nM) channels.  Association and dissociation rates of the toxin are slower for Kv1. 2/KCNA2 than for Kv1. 3/KCNA3.
What are the official names of this protein?
Potassium channel toxin alpha-KTx 2.13, Toxin Css20.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 02 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ASTE_PSEA8
Sequence: MLALGKLLDLTLAGREPTEKIQLTADGTRLHWLAEGALEVTPIGARDNGVDLLLSAGIHGNETAPIELLERLIRKVAAGTLKPAARVLFLFGNPEAIRRGERYVEQDMNRLFNGRHEEGSGNEAFRAAELERLAQVFFSKTERVHLHYDLHTAIRGSKIEQFALYPWAEGRQHSRSELARLRDAGIEAVLLQNKPGITFSAYTYGQLGAEAFTLELGKARPFGENQEVNLERLERSLELLIDGSEEQPDGSRLDGLKLFSVSREVIKHSDHFRLHLDDDVANFTELSPGYLLAEDIGGTRWVVDEVGARIIFPNPRVKNGLRAGILVVPAKL
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: FOLD_GLAP5
Sequence: MSAQIISGNKLAQQIKTQIFEHIASYVQQGYRAPGLAVILVGSDPASQVYVGSKRKTCAELGIYSESYDLPADTTETQLLSLINKLNNDEKIDGILVQLPLPEHVDTTKIIEAISPDKDVDGFHPYNVGRLCQRIPTLRACTPYGVMKLLETTGENLYGKHAVIVGASNIVGRPMALELLLGGCTVTITHRFTKNLENHVRQADLLVVAVGQPNLIPGEWIKENAIVIDVGINRIGGKLVGDVEYEAASQKAKFITPVPGGVGPMTVAMLMQNTLLAYQRHINP
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RECR_FRATT
Sequence: MTSKIFSPKISAVIESLRKLPTIGKKSSQRLALYLLDKSPETAIAIANSLLDATANIKKCVYCQALTEDDVCNICSNTNRDNTKLCIIESMLDMIAIEEAGIYRGKYFVLNGRISPLDGIGPSELKLDILQQIIADRKIDEVILAISPTVEGETTAHFISQMIAKDIKISRIGFGVPFGGELEYLDQQTLLHAFNARTNI
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: GON2_MORSA
Sequence: MCVSRLVLLFGLLLCVGAQLSNAQHWSHGWYPGGKRELDSFGTSEISEEIKLCEAGECSYLRPQRRNVLRNIILDALARELQKRK
What is the function of this protein?
Stimulates the secretion of gonadotropins.
What are the official names of this protein?
Progonadoliberin-2, Progonadoliberin II.
What is the protein family that this protein belongs to?
Belongs to the GnRH family.
What are the subcellular locations of this protein?
Secreted.
Protein: PROF1_LILLO
Sequence: MSWQTYVDDHLMCDVDGQHLTASAIVGHDGSIWAQSAGFPQFKPEEITGIMNDFAEPGSLAPTGLYLAGMKYMVIQGEPGAVIRGKKGSGGVTIKKTGQALIFGIYEEPMTPGQCNMVVERMGDYLVDQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
What are the official names of this protein?
Profilin-1.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RL3_MYCA1
Sequence: MARKGILGTKLGMTQVFDENNRVVPVTVVKAGPNVVTRIRTPEQDGYSAVQLAYGEISPRKVNKPVTGQYAAAGINPRRFLAELRLDNPDAAAEYQVGQELTAEIFTDGSYVDVTGTSKGKGFAGTMKRHGFRGQGASHGAQAVHRRPGSIGGCATPARVFKGTRMAGRMGNDRVTVQNLLVHKVDTENGVLLIKGAVPGRTGGLVMVRSAVKRGEK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: NSRR_ECOK1
Sequence: MQLTSFTDYGLRALIYMASLPEGRMTSISEVTDVYGVSRNHMVKIINQLSRAGYVTAVRGKNGGIRLGKPASAIRIGDVVRELEPLSLVNCSSEFCHITPACRLKQALSKAVQSFLTELDNYTLADLVEENQPLYKLLLVE
What is the function of this protein?
Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress.  May require iron for activity.
What are the official names of this protein?
HTH-type transcriptional repressor NsrR.
Protein: NDHK_PROMA
Sequence: MNNIPSIEAVKDIRSGTCGPVAAPAVTSDLSENIILTSLDDLHNWARLSSLWPLLYGTACCFIEFAALIGSRFDFDRFGLVPRSSPRQADLLIVAGTVTMKMAPALVRLYEQMPDPKYVIAMGACTITGGMFSADSTTAVRGVDKLIPVDLYLPGCPPRPEAIFDAVIKLRKKVGNESFLERKKITQTHRYFTITHKMKRINPLVNGSYLNAKTQKAALKAGDDISLPTKSESIETTTKELN
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, NAD(P)H dehydrogenase I subunit K, NDH-1 subunit K, NDH-K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CRN_DROME
Sequence: MERPQKMPKVAKVKNKAPAEVQITAEQLLREAKERDLEILPPPPKQKISDPAELADYQQRKRKTFEDNLRKNRMVVSHWIKYAQWEEQQQEIQRARSIWERALDNEHRNVTLWLKYAEMEMKNKQVNHARNLWDRAVTIMPRVNQFWYKYTYMEEMLENVAGARQVFERWMEWQPEEQAWQTYVNFELRYKEIDRAREIYERFVYVHPDVKNWIKFARFEESHGFIHGSRRVFERAVEFFGDDYIEERLFIAFARFEEGQKEHDRARIIYKYALDHLPKDRTQELFKAYTKHEKKYGDRAGIEDVIVSKRKYQYEQEVAANPTNYDAWFDYLRLIEAEGDRDQIRETYERAISNVPPANEKNFWRRYIYLWINYALYEELEAEDAERTRQIYKTCLELIPHKQFTFSKLWLLYAQFEIRCKELQRARKALGLAIGMCPRDKLFRGYIDLEIQLREFERCRMLYEKFLEFGPENCVTWMKFAELENLLGDTDRARAIFELAVQQPRLDMPELLWKAYIDFEVALGETELARQLYERLLERTQHVKVWMSFAKFEMGLSHGDSGPDAELNVQLARRIYERANEMLRQLGDKESRVLLLEAWRDFERDASDSQEMQKVMDKMPRRIKKRQKIVSDNGVEEGWEEVFDYIFPEDEMARPNLKLLAAAKMWKTQKDNTVDDPPATAIASEPEPAADAAPADTTDSGD
What is the function of this protein?
May be involved in pre-mRNA splicing process (PubMed:12163015, PubMed:2044955).  Involved in embryonic neurogenesis and cell rearrangement during Malpighian tubule morphogenesis (PubMed:2044955, PubMed:10502111).
What are the official names of this protein?
Protein crooked neck.
What is the protein family that this protein belongs to?
Belongs to the crooked-neck family.
What are the subcellular locations of this protein?
Nucleus speckle. Note=Concentrated in nuclear speckles.
Protein: KTHY_STRE4
Sequence: MTRGKLITFEGPDGAGKTTVLERLVPLLQAALGQTIVTTREPGGVAIAEKIRQLILDVSHTTMDDKTELLLYIAARRQHLVEKIMPALESGHLVLVDRFIDSSVAYQGAGRGLDKQAIQWLNHFATDGVDPDLTLYFDVPSELGLARIAQNTEREINRLDLEQLDLHQRVRKGYLELALENPQRIVKIDASQDLESVVSAALAAIITHSQA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: PYRB_PHOPR
Sequence: MANSLFQKHIISIPELNRSELELIVETAGILKAEPNPELLKNKVVASCFFEPSTRTRLSFETAVQRLGGTVIGFDNGGNTSLAKKGETLADSVQVISSYVDAFVMRHPQEGAARLASEFSNGVPIINGGDGANQHPTQTLLDLFSIFETQGRLDNLNVAFVGDLKYGRTVHSLTQALSKFNNINFFFVAPEILAMPDYICEELDEAGINYSLHASMEEVIPELDVLYMTRVQKERFDESEYAHMKAAYILTADMLAEARDNMKILHPLPRIDEITVDVDKTKHAYYFQQAENGVYAREALLALVLNEQL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: GMT2_CRYNJ
Sequence: MASYTPSSSRPHTPLGLSPRGSYTNLASAAYDASSPGGHGAKDEKERLRAEREVQEALLKAQDGVEKAKKEEVCMPASTTVLPILSYCVASIMMTVVNKFVVSGRQFTMTFLLLAIQSFVCVACVWLAKRIGVINFRDWDMNDAKAWFPVSSLLVAVIYTGSKSLQFLSIPVYTIFKNLTIILIAYGEVIWFGGHVTPLTLCSFFLMVGSSVIAAWADISTTLSKLSAGVAVVDPISGADVPLSSISVMDTMNVGYLWMFINCLASAGYVLFMRKRIKVTGFKDWDSMFYNNLLSIPVLFVFSLIIEDWGAASFSRNFPEEGRAFLLSAIAFSGAAAVFISYSTAWCVRICGATTYSLVGALNKLPVAASGILFFGDPVNFGNVSAILVGGVSGIVYAVAKTNQAKVEKSKQARGGESKA
What is the function of this protein?
Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.
What are the official names of this protein?
GDP-mannose transporter 2, GMT 2.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. SLC35D subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SECA_LEPBJ
Sequence: MNMIQNILRVILGSKFERDLKKLVPIVGQINSLEKEMKETSDSLLSSQTQKFRERIARGESLDSILPEAFATVREVSLRTMGMRHFDVQMMGGIALHRGNIAEMKTGEGKTLTSTLAVYLNSLAGKGVHVVTVNDYLAKRDANWMKPIYDFLGISVGVIQHDMDHEQRKIAYSADITYGTNNEFGFDYLRDNMVSHKDHKVQRSHFFAIVDEVDSILIDEARTPLIISGSSDETTDKYVRINKIIPKLVAIEDFEVDEKARNVLLSEKGVSHVEEILGIENLYAPENVDLVHHVHQALKAHKIFQKDVDYVVQNGEVIIVDEFTGRLMAGRRYSDGLHQALEAKESVTIAKESQTLASITFQNYFRMYDKLAGMTGTADTEAEEFRKIYDLDVIVIPPNVSVRRKDSPDRVYRTEKEKFDAILAEIRELQSKKQPVLVGTISIEKSEILSKMLSSAGIQHNVLNAKFHEREAEIVANAGKPGAVTIATNMAGRGTDIVLGGAQLYKENLETWKDDDDLVRRFKESILKQELDNAELLIREMDSSVKQKRASEILESVKIWKKNHEDVLVAGGLHILGTERHEARRIDNQLRGRSGRQGDPGSSRFYLSLQDDLMRIFGSDRISGLMKWANMPEGQEIESKMVSNAIARAQKRVEGHNFDIRKHLLEYDDVMNRQRIVIYKMRNEVLENEDISSLILSFIEEAVENQIVAHCEGNNPSSWNLDSLKEWLEGLELNLEINEEDFKKTKNPQLALFEKVNAAAKQKYEDRAESIGKDIWKLLERNIFLDILDHRWKEHLYSMDHLREGIWTVGYSERNPLVEYKLQGFRMFDVAIENLKNEVVNFLFRVEVSENSKLPEERREYKKVGQEVTGGFQELSSGTPSPTVTVTTSSGGGTERKTSRRRKR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: MUTS_STAA1
Sequence: MSNVTPMMQQYLKIKSEYQDCLLFFRLGDFYEMFYEDAKEASRVLEITLTKRDAKKENPIPMCGVPYHSADSYIDTLVNNGYKVAICEQMEDPKQTKGMVRREVVRIVTPGTVMEQGGVDDKQNNYILSFVMNQPEIALSYCDVSTGELKVTHFNDEATLLNEITTINPNEVVINDNISDNLKRQINMVTETITVRETLSSEIYSVNQTEHKLMYQATQLLLDYIHHTQKRDLSHIEDVVQYAAIDYMKMDFYAKRNLELTESIRLKSKKGTLLWLMDETKTPMGARRLKQWIDRPLISKEQIEARLDIVDEFSAHFIERDTLRTYLNQVYDIERLVGRVSYGNVNARDLIQLKHSISEIPNIKALLNSMNQNTLVQVNQLEPLDDLLDILEQSLVEEPPISVKDGGLFKVGFNTQLDEYLEASKNGKTWLAELQAKERQRTGIKSLKISFNKVFGYFIEITRANLQNFEPSEFGYMRKQTLSNAERFITDELKEKEDIILGAEDKAIELEYQLFVQLREEVKKYTERLQQQAKIISELDCLQSFAEIAQKYNYTRPSFSENKTLELVESRHPVVERVMDYNDYVPNNCRLDNETFIYLITGPNMSGKSTYMRQVAIISIMAQMGAYVPCKEAVLPIFDQIFTRIGAADDLVSGKSTFMVEMLEAQKALTYATEDSLIIFDEIGRGTSTYDGLALAQAMIEYVAETSHAKTLFSTHYHELTTLDQALPSLKNVHVAANEYKGELIFLHKVKDGAVDDSYGIQVAKLADLPEKVISRAQVILSEFEASAGKKSSISNLKMVENEPEINQENLNLSVEETTDTLSQKDFEQASFDLFENDQESEIELQIKNLNLSNMTPIEALVKLSELQNQLK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RL15_CERSK
Sequence: MKLNELRDNEGAARKKKRVARGPGSGKGKTAGRGIKGQKSRSGVALNGYEGGQMPLYRRLPKRGFTKPNRKEYAVVNLGLIQKFVDAGKLDASQPIDENAIVAAGVTSHKRDGIRVLAKGEITAKLALTVSGASKSAVEAIEKAGGSITLTAPAAAAASAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: FADR_SHESM
Sequence: MIINAKGPASFAEKYIVRSIWENKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLKIQHGKPTRVNNFWETSGLNILETIADLNPEGFPVLVDQLLSARTNVSAIYFRGALRNSPDTAVEVLAQIHQLEDTAESFAEYDYLLHHTLAFSSGNPLYVLILNGFKGLYSRVGRYYFSSPEARQLALNFYKELEVLAKAKNYVDVPALMRTYGINSGKMWLQLRDDMPTSIALQEANS
What is the function of this protein?
Multifunctional regulator of fatty acid metabolism.
What are the official names of this protein?
Fatty acid metabolism regulator protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTH_AGRRK
Sequence: MTITLHPGSVSLKQLAEIYWSGEPAKLDASFDAGILKAAARIAEIAAGNAPVYGINTGFGKLASIKIDSADVATLQRNLILSHCCGVGQPLPENVVRLIMSLKLVSLGRGASGVRLELVRLIEGMLAKGVVPVIPEKGSVGASGDLAPLAHMTAVMMGHGEAFYAGERLDGAAALEKAGLTPVVLAAKEGLALINGTQVSTALALAGLFRAHRAAQAALITGAMSTDAAMGSSAPFHPDIHTLRGHQGQIDTAAALRGLLAGSVIRESHIEGDERVQDPYCIRCQPQVDGACLDLLRSVGRTLEIEANAVTDNPLVLSDNSVVSGGNFHAEPVAFAADQIAIAVCEIGAISQRRIALLVDPALSYGLPAFLAKKPGLNSGLMIAEVTSAALMSENKQMSHPASVDSTPTSANQEDHVSMACHGARRLLQMTDNLFGIVGIEALTAAQGVEFRAPLATSPELTLAIATIRSVVPTLDVDRYMANDLKAASDLVASGALNASVSADILPSLEI
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECFA2_MESFL
Sequence: MQINKKEIKQNLKKWNEEKKSIKSFSFTGDIILDNVSYTYSKKTPFEFRALDNADLTISDKKITCVIGTTGSGKSTMIQLTNGLLISETGQTIVGDYKIPAGLKKIKEVKDLRREVGLVFQFPEYQLFQDTIEKDIAFGPIHLGADKEEVYKKIPELLDLVSLPREYAKRSPFELSGGQKRRTAIAGIIAMDGKTLVLDEPTGGLDPKGEEDFMNLFLRLNKNQGKRIIMVTHNMDQVLKVADEVIVMHEGKVISKGSPFEIFSNQELLSKIQIEPPKLYKLMYKLKEKGTDLLNKNIRTIDEFAKAFKEVRKGK
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA2, ECF transporter A component EcfA2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.