PharMolix/UniProtQA huggingface dataset:
Protein: TOLB1_NOVAD
Sequence: MTLRMLFAFALLAAAPAQAQQTEPQPAEEGGLSGTVSDDSEWQDLGIAIPAFATNADVPTPTSAGSTSALGQALAQVISANLRNNGLFKPVGPESLPRPGFEQVQAPDFAVWSARSAEMLVQGYVRANGDGQLTVGCYLYDVALKQQLEKAGWTVAPADWRRAAHKCADMIYARLSGESPFFDSRVAYIAESGPKDRRMKRLAIMDSDGANHRYLTSGQATALTPRFSPDYKSILYLSYLNGRPRIYVYDLAANTQRLVTETPGPTFAPRWSPDGKWILYSMATAGNTDIYKVPASGGASQRLTDTPGIDVGGSFSPDGSRIVFESDRSGSQQIYVMNADGSDHRRISFFGGRAATPEWSPRGDQIAFTHIVGNLRIAVVSPGGGDLRYLTDSWQDEAPTWSPNGRIIQFFRTEKGSGKASVWQVDLTGRNERRLSTPGDASDPAWGPLLP
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB 1.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y1445_BACMK
Sequence: MNTPVSVNEKKDFVKWFLNNYQLKQRECVWILNYLMSHDQLMHKVHFVEHAKYCPRGLVMSANCVKDTPFHFFKQNVMTTDAEKSFHDIRLNRDEDIYIQLNFKSSFQNANYVAVLEENPYLPKHIEVNEKDRLLAERFLEESVFSFRRERLLKQIDEALDKQDKEAFHRLTAELKIL
What are the official names of this protein?
UPF0302 protein BcerKBAB4_1445.
What is the protein family that this protein belongs to?
Belongs to the UPF0302 family.
Protein: SEY11_ENTH1
Sequence: MQESDVFHNQLRVEMLKKEEDEVENNSEKKKAPGIDMNKVNLIKTRDEDIIAENIKAELKEEEKENMKVEEEEIKEEEEKKEKENYPCMQIIDQEGIFADENQKDRITFEEFIQENTKFKELGFNYNMLSILGPQNSGKSTLLNYLFDTDFAVLNEKNGRQRTTRGVWLGLVGDRKDIIIMDLEGSDGSIREDDLSFERKISLFSLSVCSVLMVNIWSHDVGRYGASNMSLLKNIFELNLQLFQKEDSPKTLILFVIRDRDQRKPFENTKSVLLEDIMKIWESVARPECFKRAPIDKFFDLEFTSLPHFKHDKELFIQEAKELKKRFDCKNQNTYFRPIYNKEIPADGLALFTKQVWSAIKSNKDLDLPSQKEMLARFRCDELIENIFNEFEKEIEEIKLQHSEKHIFNNFKIFCDCLYDKKMKEFMNVASKYLDRVVKEKADLLSEKMLNEISYLFQTQMTLAINYIKTMLTTSYFTLKNQYITEQSSLFDPTKYAGYAEQMDDFNSTIKNEWEKISTQSVPSNIENNFEIEINTLDRFINKLYEIGRRDLIEALMTHFKKHLQNIMKPLLLPLFEQSNQNMWEQVRKVVIETTSQNLQELENGMINSLKMNKDDVEKKLNELQVYIIDAVRSTILERPGFVSNLMENKFISIFRLDDEGLPKKWKQNEDLSKPFFKAKEEAEKILDLFSYIRMDPKDDELSFISINPATGKKMIIEEPENGTIDQTKVLFSLSERLSIYEGFQNMAESNFIRAQQELAAITVHSKTPMWLILLIAFLSFDNIVYVFKSPTLLALTLIIIGIIYSLNKIGYAYLIDSVISYILSISWSSVLYLIQDLGLFKNLLPKPEAPKRKRPQKKTQDDKPKSSILLTHKKQPSVMGDVTMDNIDSLNSFDDAFKLVSQDEKPIRKPLHPLPKRETQSMKVMPMSASFTKSQSMFIKRNPTTTSSLNKIKEANEF
What is the function of this protein?
Probable GTP-binding protein that may be involved in cell development.
What are the official names of this protein?
Protein SEY1 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
Protein: APT_LEPIC
Sequence: MSIVKSKIRTIPDYPKPGILFRDITSLLLDPEGLALTIGTFVNRYQGKGITKVAGIEARGFLTGAPLAFQLGVGFIPIRKKGKLPSETVSEEYDLEYGKDVIEVHKDSIQPGDKILLMDDLIATGGTMIAAVKLLKKLGAEIYEAGVIIDLPDLGGRKKLQEELKVPVFSICEFEGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYW_STAEQ
Sequence: METLFSGIQPSGIPTIGNYIGALKQFVDVQDDYECFFCIVDQHAITVPQDRLKLRKQIRQLAAIYLASGIDPDKSTLFIQSEVPAHVQAGWMLTTIASIGELERMTQFKDKAQKRADGVPAGLLTYPPLMAADIVIYNTNIVPVGDDQKQHMELTRNLVDRFNSRYNDVLVKPEVRMPKVGGRVMSLQDPTKKMSKSDDNQKNFISLLDEPHVAAKKIKSAVTDSDGIIKFDRENKPGISNLLSIYSGLTNDSIKNIESKYEGEGYGKFKGDLSEIVKDFLINFQEKYASFYNSDDLDDILDKGKEKAQKASFKTLKKMEKAMGLGRKR
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPI4_ARATH
Sequence: MVTATASTPFSLSSSVVFTRRRNFKRFPVCASLSPEVSPLLRAAHHTVDNYVKSGMIIGLGSGEASDFAIRYLGQQLGSGSLHNVVGVPMSARSASEAAKYGIPLEYYRDGVQIDFAFHDADAVEENTLIAVIGRRRSSQEDDYILKQKSIVKVADEAVFMIKEEQYKAGLEGSIPVLVQSLNWLAIAEEIDDLYLGDAEVWRRASVENEGPLGGDFPIVTSDGHNILDVIFTTPIRSLADLATSLDKIDGVVDHGLIIKTRCTVVIAEETVVRSVTLQTSALEGGVRTYGQTLQK
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Probable ribose-5-phosphate isomerase 4, chloroplastic, Phosphoriboisomerase 4.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: 3SA7_NAJHA
Sequence: LKCHKLVPPFWKTCPEGKNLCYKMYMVATPMLPVKRGCINVCPKDSALVKYMCCNTNKCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kills the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity.
What are the official names of this protein?
Cytotoxin 7, Toxin CM-4B.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: Y1549_MYCTO
Sequence: MGRHGSRWSRPPCFRVLRLWTYAHRCDLGHTDPLSRRTEMTTTERPTTMCEAFQRTAVMDPDAVALRTPGGNQTMTWRDYAAQVRRVAAGLAGLGVRRGDTVSLMMANRIEFYPLDVGAQHVGATSFSVYNTLPAEQLTYVFDNAGTKVVICEQQYVDRVRASGVPIEHIVCVDGAPPARSR
What are the official names of this protein?
Uncharacterized protein MT1599.1.
Protein: ECFA2_OENOB
Sequence: MEILFKNVDYIYQPNSPFQFKALTDVNLKIESGSFMAIIGKTGSGKSTLIRHLNGLLKPSSGEVKIGNLTITSSIKESQLSDLRRKVGMLFQFPEQQLFADTVEHDIEFGPINFGTTKEKAKKIARESLKKVGLNDEFLNRSPLELSGGQMRRVALAGVLAVKPDILVLDEPTAGLDFIGKKEIMKLIKKLQLEEHTTIILVSNSMEDVADYAEEVILLSKGKVIKQASPNKIFSNKEITSALGIETPQTTVLAEFLLERGVDFKGSLPINEKSFNNFLKKIFEEKKKTRIL
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA2, ECF transporter A component EcfA2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS14Z_HALSA
Sequence: MSETDGEAEETGQTHECRRCGREQGLVGKYDIWLCRQCFREIARSMGFKKYS
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: GLMM_STAAE
Sequence: MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIALDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: AGLUS_THENN
Sequence: MAKRKVPAEFVVERDDYKCIRCLACVRVCSYGANYYDENANRVYTENYKCVGCHFCEAICPTEAITVRRNNFDIRPLAHWTPEHLIGIMKQADTGGVLLTSMGNDRPYFSYFDRIVLNASQVTNPSIDPLREPMEIRTYIGRKEAKLEIEEDGEGNVALKTEIAPQLKLEVPVMFTAMSYGSISLNALLSLARAARTIGTFFNTGEGGLPKELREFKDNMIVQVASGRFGVSADYLNAGSAVEIKIGQGAKPGIGGHLPGEKVTEPISETRMIPVGTDALSPAPHHDIYSIEDLRQLIYAIKEATRYEKPVGVKIAAVHNVAPIAAGMVRAGADYIVIDGIRGGTGAAPKVTRDHVGIPIEFAIAVVDQRLREEGIRHMASIVVAGGIRNSADVIKAIALGADAVYIGTAALVALGCHLCQTCYLGKCNWGIATQDPKLTKRLNPEIGARRAANLLRAWAHEIKEILGGMGINAIESLRGNREALRGVGLHEYELKLLGIKPAGEAW
What are the official names of this protein?
Archaeal-type glutamate synthase [NADPH], Archaeal-type NADPH-GOGAT.
What is the protein family that this protein belongs to?
Belongs to the glutamate synthase family.
Protein: TM9S4_PONAB
Sequence: MATAMDWLPWSLLLFSLICETSAFYVPGVAPINFHQNDPVEIKAVKLTSSRTQLPYEYYSLPFCQPSKITYKAENLGEVLRGDRIVNTPFQVLMNSEKKCEVLCSQSNKPVTLTVEQSRLVAERITEDYYVHLIADNLPVATRLELYSNRDSDDKKKEKDVQFEHGYRLGFTDVNKIYLHNHLSFILYYHREDMEEDQEHTYRVVRFEVIPQSIRLEDLKADEKSSCTLPEGTNSSPQEIDPTKENQLYFTYSVHWEESDIKWASRWDTYLTMSDVQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDIANYNKEDDIEDTMEESGWKLVHGDVFRPPQYPMILSSLLGSGIQLFCMILIVIFVAMLGMLSPSSRGALMTTACFLFMFMGVFGGFSAGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGKHSSGAVPFPTMVALLCMWFGISLPLVYLGYYFGFRKQPYDNPVRTNQIPRQIPEQRWYMNRFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWWRNFLVSGGSAFYVLVYAIFYFVNKLDIVEFIPSLLYFGYTALMVLSFWLLTGTIGFYAAYMFVRKIYAAVKID
What is the function of this protein?
Associates with proteins harboring glycine-rich transmembrane domains and ensures their efficient localization to the cell surface.
What are the official names of this protein?
Transmembrane 9 superfamily member 4.
What is the protein family that this protein belongs to?
Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Golgi apparatus. Early endosome.
Protein: VATC_DEIRA
Sequence: MGDSSGSRPTWPRRSAACSRNKVGKDCMPDDYSYINTRVRVMRTKLLDGRALDAALASGSYQEFLRVLSETDFAPNMRETTAEGAGLPELDRALSQNLFDTTQRVLGFADGDAKREIETLLMKWDLTNLKTLARGIVSGRGAETIQQNLIPGGTIKPSVLQTASQSTDLASAATALGVGGHPLAKVFRNAVTAYNTTGRLLDLEVLLDQGYYRYATQVSRDTSLRRYLSREIDITNALIARNSRGGTLDTNLFVPGGSLDAAGYGRLGAGDAGGNADITAILEAPSIEDAEVAARTALDRAARSSAVSDVEGVGIILDFLRRKEIEVAKLRLIGRGKYYDLPTDEIRREVQA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit C, V-ATPase subunit C.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase V0D/AC39 subunit family.
Protein: ACP_BORGP
Sequence: MDNDEIFSKVRSIISEQLDKKEDEITIDSRFVEDLNADSLDIYELLYLLEEAFDDKIPENEANEFETVGDVVNFIKKRKG
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODM_PIG
Sequence: HINAQIMQLHHSEHHAAYVNNLNVVEEKYQEALKKGDVTAQVALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEAIKRDFGSFEKFKEKLTAVSVGVQGSGWGWLGFNKEQGRLQIAACSNQDPLQGTTGLVPLLGIDV
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn], mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: HBA_RABIT
Sequence: MVLSPADKTNIKTAWEKIGSHGGEYGAEAVERMFLGFPTTKTYFPHFDFTHGSEQIKAHGKKVSEALTKAVGHLDDLPGALSTLSDLHAHKLRVDPVNFKLLSHCLLVTLANHHPSEFTPAVHASLDKFLANVSTVLTSKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-1/2, Alpha-1/2-globin, Hemoglobin alpha-1/2 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: ARGJ_STAAN
Sequence: MKHQETTSQQYNFSIIKHGDISTPQGFTAGGMHIGLRANKKDFGWIYSSSLASSAAVYTLNQFKAAPLIVTEDTLQKSKGKLQALVVNSANANSCTGQQGIDDARQTQTWVAQQLQIPSEHVAVASTGVIGEYLPMDKIKTGTEHIKDTNFATPGAFNEAILTTDTCTKHIAVSLKIDGKTVTIGGSAKGSGMIHPNMATMLAFITTDASIESNTLHQLLKSSTDHTFNMITVDGDTSTNDMVLVMANHQVEHQILSQDHPQWETFVDAFNFVCTFLAKAIARDGEGATKLISVNVSGAKSISDARKIGKTIVSSNLVKSAIFGEDANFGRIITAIGYSGCEIDPKCTYVQLNQIPVVDKGMAVLFDEQAMSNTLTHEHVTIDVQLGLGNAAATAYGCDLSYDYVRINASYRT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPA_DESVH
Sequence: MQLMEYTQLALFLGLLALMSPVLGRFIGRAVLRGEQTWMHSVLGPVERLIYRASGIRPEARQSWRQYAASLCAFSAAGFLMTFGVLMLQDKLPLNPQGFPGLSWHLAFNTAVSFLTNTNWQSYAGESTVSHFSQMVGLAYHNFVSAAAGLAVAVAVMRGLASQESKTIGNFWADLVRSVLYVLLPISLVLAVVLVGQGVVQTMSAGTEVATLEGGRQFIAMGPTASQVAIKMLGTNGGGFFNANAAHPLENPTALSNLLQMLAIFIIPSSLVFTLGGAVSNRRHAWTVWFVMACLFMVGACSLYRAETLGTPLLTEVAQAPVTNMEGKEVRFGIFGSAMFATVTTDASCGAVNAMHDSLTPLGGLVTLVNMQMGEVIFGGVGSGLYGMVLFILLTVFLAGLMVGRTPDYLGKRIEGREVTLAMLALIIAATPPLLFSAVAAVSGWGQAALNNAGAHGFSEILYAYTSGVQNNGSAFAGLNANSPAWNVTIALAMLIGRFGIMLPMLGVAGSMASRKARPIGEFSFPVSGFTFGLLLTLVIVIVGALTYLPALALGPVVEHFQMLDGLLH
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NRDI_STRP8
Sequence: MAELIIVYFSSKSNNTHRFVQKLGLPAQRIPVDNRPLEVSTHYLLIVPTYAAGGSDAKGAVPKQVIRFLNNPNNRKHCKGVISSGNTNFGDTFALAGPIISQKLQVPLLHQFELLGTATDVKKVQAIFARLKHHTHDKQKQTNNLITERTHPCHKPMRHTSH
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: YOPM_YERPE
Sequence: MFINPRNVSNTFLQEPLRHSSNLTEMPVEAENVKSKTEYYNAWSEWERNAPPGNGEQREMAVSRLRDCLDRQAHELELNNLGLSSLPELPPHLESLVASCNSLTELPELPQSLKSLLVDNNNLKALSDLPPLLEYLGVSNNQLEKLPELQNSSFLKIIDVDNNSLKKLPDLPPSLEFIAAGNNQLEELPELQNLPFLTAIYADNNSLKKLPDLPLSLESIVAGNNILEELPELQNLPFLTTIYADNNLLKTLPDLPPSLEALNVRDNYLTDLPELPQSLTFLDVSENIFSGLSELPPNLYYLNASSNEIRSLCDLPPSLEELNVSNNKLIELPALPPRLERLIASFNHLAEVPELPQNLKQLHVEYNPLREFPDIPESVEDLRMNSERVVDPYEFAHETTDKLEDDVFE
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.
What are the official names of this protein?
Outer membrane protein YopM.
What is the protein family that this protein belongs to?
Belongs to the LRR-containing bacterial E3 ligase family.
What are the subcellular locations of this protein?
Cell outer membrane. Secreted.
Protein: PRL_SPAAU
Sequence: MAHRETNGSKLFITVLCMVAACSAVPINDLLDRASQRSDMLHSLSTTLTKDLSNHVPPVGWTMMPRPPLCHTSSLQTPNDKEQALQLSESDLMSLARSLLQAWQDPLVDLSNSANSLLHPSQSSISNKIRELQEHSKSLGDGLDILSGKMGPAAQAISSLPYRGSNDIGEDNISKLTNFHFLLSCFRRDSHKIDSFLKVLRCRAAKVQPEMC
What are the official names of this protein?
Prolactin, PRL.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CM3B_CONBU
Sequence: MMSKLGVLLTICLLLFPLFALPQDGDQPADRPAERMQDDISSEQNPLLEKRVGERCCKNGKRGCGRWCRDHSRCCGRR
What is the function of this protein?
Mu-conotoxins block voltage-gated sodium channels (Nav).  This synthetic toxin potently blocks rNav1. 4/SCN4A (Kd=0. 34-3. 6 nM), rNav1. 2/SCN2A (Kd=13 nM), rNav1. 3/SCN3A (Kd=200 nM), rNav1. 1/SCN1A (Kd=360 nM), mNav1. 6/SCN8A (IC(50)=1. 8 uM), rNav1. 5/SCN5A (IC(50)=9 uM), rNav1. 6/SCN8A (IC(50)>30 uM) (PubMed:18950653, PubMed:21652775, PubMed:25632083, PubMed:23557677).  It is noteworthy that the toxin is 50-fold more potent on mouse Nav1. 6 than on rat Nav1. 6 (PubMed:25632083).  The block of SCN4A is very slowly reversible (PubMed:18950653).
What are the official names of this protein?
Mu-conotoxin BuIIIB, Conotoxin Bu16.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: UBIG_SHISS
Sequence: MNAEKSPENHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNPITNSFKLGPGVDVNYMLHTQNK
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: SOBP_RAT
Sequence: MAEMEKEGRPPENKRSRKPAHPVKREINEEMKNFAENTMNELLGWYGYDKVELKDGEDIEFRSYTTDGESRQHISVLKENSLPKPKLPEDSVISSYNISTGYSGLATGNGLSDSPAGSKDHGNVPIIVPLIPPPFIKPPAEDEVSNVQIMCAWCQKVGIKRYSLSMGSEVKSFCSEKCFAACRRAYFKRNKARDEDGHAESFPQQHYAKETPRLAFKNNCELLVCDWCKHIRHTKEYLDFGDGERRLQFCSAKCLNQYKMDIFYKETQANLPAGLCGTLHPHMESKAEGTGVQLLTPDSWNIPLTDARRKAPSPVAAAGQSQGPGPSSSTTVSPSDTANCSVTKIPTPVPKSLPISETPSIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIIQQIRPPFIRGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVNDSKPPNGFSSNGESFVPSAPGDSSAAGGKAGGRSLSPRDSKQGSSKSADSPPGSSGQALSLAPSERGRGEVVDLTRRAASPAGAGGQPGFAGVLHGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREPGAAERRTCGGCRDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRSAPAEAKGAEPPPEQPPPPAPPKKLLSPEEPAVNELESVKENNCASNCHLDGEVTKKLMGEEALAGGDKSDPNLNNPADEDHAYALRMLPKTGCVIQPVPKPAEKAAMTPCVISSPMLSAGPEDLEPPLKRRCLRIRNQNK
What is the function of this protein?
Implicated in development of the cochlea.
What are the official names of this protein?
Sine oculis-binding protein homolog, Jackson circler protein 1.
What is the protein family that this protein belongs to?
Belongs to the SOBP family.
Protein: Y038_SIFVH
Sequence: MSLCLREIGNKKVLYIPKQLEDNFDEGRVYPIIVEGKIVGLKCIRTAKRKCLYIPKQLEDLFKDGCYSFEYLKA
What are the official names of this protein?
Uncharacterized protein 38.
Protein: UXUA_SALPK
Sequence: MKQTWRWYGPNDPVTLSDVRQAGATGVVTALHHIPNGEIWSVDEIQKRKAIVEEAGLEWSVVESVPIHEDIKTHTGQYDLWIKNYQQTLRNLAQCGIYTVCYNFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFELHILKRPGAEADYTAEEIAQAERRFATMSEEDKARLTRNIIAGLPGAEEGYTLEQFRQHLATYKDIDKAKLREHFAYFLKAIIPVADEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVETVNSMANGFTMCTGSYGVRADNDLVDMIKQFGPRIYFTHLRSTLREENPKTFHEAAHLHGDVDMYEVVKAIVEEEHRRKAEGSDDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFFSK
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: RALA_SAGOE
Sequence: MAANKPKGQNSLALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDLEDKRQVSVEEAKNRADQWNVNYVETSAKTRANVDKVFFDLMREIRARKMEDSKEKNGKKKRKSLAKRIRERCCIL
What is the function of this protein?
Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking.  Accomplishes its multiple functions by interacting with distinct downstream effectors.  Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles.  The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling.  Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor.  Required for anchorage-independent proliferation of transformed cells.  During mitosis, supports the stabilization and elongation of the intracellular bridge between dividing cells.  Cooperates with EXOC2 to recruit other components of the exocyst to the early midbody.  During mitosis, also controls mitochondrial fission by recruiting to the mitochondrion RALBP1, which mediates the phosphorylation and activation of DNM1L by the mitotic kinase cyclin B-CDK1 (By similarity).
What are the official names of this protein?
Ras-related protein Ral-A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cleavage furrow. Midbody, Midbody ring. Mitochondrion. Note=Predominantly at the cell surface in the absence of LPA. In the presence of LPA, colocalizes with LPAR1 and LPAR2 in endocytic vesicles. May colocalize with CNTRL/centriolin at the midbody ring. However, localization at the midbody at late cytokinesis was not confirmed. Relocalizes to the mitochondrion during mitosis where it regulates mitochondrial fission.
Protein: RL1_FRATT
Sequence: MAKVSKRMKEISAKINAEKKYPVSEAFDLLREVSSVKFVESVDVSVALGVDPRKSDQVVRGASVLPNGTGKTVRVAVFAKGPAADAAKEAGAEVVGMEDLADEVKKGNMDFDVVIASPDSMRVVGQLGQILGPKGLMPNPKVGTVTMDVAKAVRDAKAGQVRYRVDKAGIIHTTIGKVNFTSDALKQNLEQLLTDLKKAKPAVSKGIYLKKVSVSSTMGPGINVDFSDLNI
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: ECOT_PSEP1
Sequence: MRPTPMTAILALSLAAAAPAMAASLKDIAPYPEAEKGFTRQVIHLPAQADESAYKLEILAGKTLQVDCNRQRLGGNLEARTLEGWGYNYYRLDNVSGPASTLMACPDGKKTEAFVPVVGDGFLLRYNSKLPVVVYVPKDVEVRYRVWSASQDVQKAKVE
What is the function of this protein?
General inhibitor of family S1 serine proteases.
What are the official names of this protein?
Ecotin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I11 (ecotin) family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MNTH_STAHJ
Sequence: MGVIDNKEQRSLDEINSTIEFNDSQRTSQKFLAFLGPGLLVAVGYMDPGNWITSMQGGAQFGYTLLFVILISSLSAMLLQSMTVRLGIATDKDLAQMTRHYLNKPTAIIFWVIAELAIIATDIAEVIGSAIALDLLFNIPLIIGALITVFDVFLLLFIMKFGFRKIEAIVGTLIFTVLMIFVFEVYISSPNLIEILNGFVPHYQIIANHSILYIALGIIGATIMPHNLYLHSSIVQSRKYNRHSFTEKAQAIKFATIDSNIQLSIAFIVNCLLLVLGAALFYGVNSNNIGGFYDLYQALRTQPVLGVVMGSIMSTLFAIALLASGQNSTITGTLAGQIVMEGFLKLSIPNWMRRLVTRSLAVIPVLLCLVIFRGNESKMEQLLVFSQVFLSIALPFSLIPLQLATSNEKLMGPFKNKKWVNICAWGLIIILSFLNIYLIIETFKEL
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.