PharMolix/UniProtQA huggingface dataset:
Protein: IHFA_ALBFT
Sequence: MPALTKAQLAELLFEKIGLNKRESKDMVDAFFDLVADSLLKGEDVKISGFGNFQIRTKAPRPGRNPRTGETIPIQARRVVTFHAGYKLKEQIQDQELVPLAP
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: HISX_PHOPR
Sequence: MKTVVWQSLSENQQESLLQRPAITEGANITAIVADVVADVRQRGDEALLELTEKFDRVRPDSIRVSEQEVTAATSRLSDNMKQALQQAYQNIATFHKAQKTKPLRVETQPGVVCEQVTRPINSVGLYIPGGSAPLPSTVLMLGVPAQIAGCRQVVLCSPPPIADEILYVAQLCGITEIYNIGGSQAIAAMAYGTKSVARVDKIFGPGNAFVTEAKRQVSNDFRGAAIDMPAGPSEVLVIADKTADPDFIAADLLSQAEHGPDSQVILLTPEPSIADRVADAIQLQLKVLPRADIARQALGSSILIVTETISQCISISNHYGPEHLIVQTREPRELVPLLDNAGSIFLGDWSPESVGDYASGTNHVLPTYGYTRTYSSLGLADFSKRMTVQELTADGLKILAPTVVTMAEAEGLDAHKRAVTIRIEKLQQQEILKAQQVEEKEA
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: MMPL3_MYCTU
Sequence: MFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQVYGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKISAAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIGGFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAGDPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPTTRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIRSDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL
What is the function of this protein?
Is the target of the antitubercular drug SQ109.
What are the official names of this protein?
Trehalose monomycolate exporter MmpL3, TMM exporter MmpL3, MmpL3 transporter, Mycobacterial membrane protein large 3.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Cell septum. Cell tip. Note=Colocalizes with TtfA to the cell poles and septa. Trehalose monomycolate (TMM) synthesis is not required for localization to the poles or septa.
Protein: SWE1_YEAST
Sequence: MSSLDEDEEDFEMLDTENLQFMGKKMFGKQAGEDESDDFAIGGSTPTNKLKFYPYSNNKLTRSTGTLNLSLSNTALSEANSKFLGKIEEEEEEEEEGKDEESVDSRIKRWSPFHENESVTTPITKRSAEKTNSPISLKQWNQRWFPKNDARTENTSSSSSYSVAKPNQSAFTSSGLVSKMSMDTSLYPAKLRIPETPVKKSPLVEGRDHKHVHLSSSKNASSSLSVSPLNFVEDNNLQEDLLFSDSPSSKALPSIHVPTIDSSPLSEAKYHAHDRHNNQTNILSPTNSLVTNSSPQTLHSNKFKKIKRARNSVILKNRELTNSLQQFKDDLYGTDENFPPPIIISSHHSTRKNPQPYQFRGRYDNDTDEEISTPTRRKSIIGATSQTHRESRPLSLSSAIVTNTTSAETHSISSTDSSPLNSKRRLISSNKLSANPDSHLFEKFTNVHSIGKGQFSTVYQVTFAQTNKKYAIKAIKPNKYNSLKRILLEIKILNEVTNQITMDQEGKEYIIDYISSWKFQNSYYIMTELCENGNLDGFLQEQVIAKKKRLEDWRIWKIIVELSLALRFIHDSCHIVHLDLKPANVMITFEGNLKLGDFGMATHLPLEDKSFENEGDREYIAPEIISDCTYDYKADIFSLGLMIVEIAANVVLPDNGNAWHKLRSGDLSDAGRLSSTDIHSESLFSDITKVDTNDLFDFERDNISGNSNNAGTSTVHNNSNINNPNMNNGNDNNNVNTAATKNRLILHKSSKIPAWVPKFLIDGESLERIVRWMIEPNYERRPTANQILQTEECLYVEMTRNAGAIIQEDDFGPKPKFFI
What is the function of this protein?
Protein kinase that acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylating and inhibiting the mitosis-promoting cyclin B-bound CDC28 at 'Tyr-19'.  SWE1-mediated inhibition of CDC28 acts in a cell size or morphogenesis checkpoint to delay mitosis in response to defects in growth, actin organization or bud formation.  Inhibits the activity of B-type cyclins in replication initiation strongly for CLB2, moderately for CLB3 and CLB4, and there is no apparent inhibition for CLB5 and CLB6, correlating with the normal expression timing of those cyclins.  Hyperphosphorylation and degradation of SWE1 when all checkpoint requirement are met releases CLB2-CDC28 from inhibition and allows for progression through the cell cycle.  SWE1-dependent CDC28 phosphorylation is also required for pachytene arrest upon activation of the recombination checkpoint during meiosis.  Also involved in the regulation of nitrogen starvation- and short chain alcohol-induced filamentous growth, or filamentous differentiation in response to slowed DNA synthesis.  Can act both on serines and on tyrosines.
What are the official names of this protein?
Mitosis inhibitor protein kinase SWE1, Wee1 homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
What are the subcellular locations of this protein?
Bud neck. Nucleus. Note=When SWE1 first accumulates in G1, it is localized to the nucleus. After bud emergence, a subpopulation is recruited to the daughter side of the mother-bud neck through HSL1 and its adapter HSL7, where it is susceptible to hyperphosphorylation and degradation.
Protein: DRT1_PHYBI
Sequence: MAFLKKSLFLVLFLGLVPLSLCESEKREGENEEEQEDDQSEEKRSLGSFLKGVGTTLASVGKVVSDQFGKLLQAGQG
What is the function of this protein?
Possesses a potent antimicrobial activity against Gram-positive bacteria B. megaterium, C. glutamicum and S. aureus and mollicutes A. laidlawii and S. melliferum (PubMed:10880984).  Less active against Gram-negative bacteria B. cepacia, P. aeruginosa, S. typhimurium and S. meliloti.  Probably acts by disturbing membrane functions with its amphipathic structure (PubMed:10880984).
What are the official names of this protein?
Dermatoxin-B1, DRT-B1, Dermatoxin.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermatoxin subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: RL2_RALPJ
Sequence: MALVKTKPTSPGRRSMVKVVNPDLHKGAPHAPLLEKQIQKSGRNNNGHITTRHKGGGHKHHYRVVDFKRNDKDGIPAKIERLEYDPNRSANIALVLFADGERRYIIAPKGAVVGQAIANGSEAPIKAGNNLPIRNIPVGTTIHCVEILPGKGAQVARSAGTSAVLLAREGIYAQVRLRSGEVRRVHIECRATIGEVGNEEHSLRQIGKAGATRWRGIRPTVRGVVMNPVDHPHGGGEGKTAAGRDPVSPWGTPTKGYRTRRNKRTDSMIVQRRHKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: GLPE_HUMAN
Sequence: MYGKIIFVLLLSGIVSISASSTTGVAMHTSTSSSVTKSYISSQTNGITLINWWAMARVIFEVMLVVVGMIILISYCIR
What is the function of this protein?
This protein is a minor sialoglycoprotein in human erythrocyte membranes.
What are the official names of this protein?
Glycophorin-E.
What is the protein family that this protein belongs to?
Belongs to the glycophorin-A family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: GRIN1_HUMAN
Sequence: MDTAEDPAWLQLLQKDSSPPGPRPTAFFCPQDGSLGAGSSAMRDYCPSQQKASPAPPRHTPDQSPGMESRHRSPSGAGEGASCSDGPRGSLACPSPTCFSPQESPSKETLEAHGASISGTPEATTSGKPEPVSSVKTEPKSSDDRNPMFLEKMDFKSSKQADSTSIGKEDPGSSRKADPMFTGKAEPEILGKGDPVAPGRMDPMTVRKEDLGSLGKVDPLCSSKTYTVSPRKEDPGSLRKVDPVSSDKVDPVFPRKEEPRYSGKEHPVSSEKVAPTSAEKVDLVLSGKRDPGPSGKADPMPLESMDSASTGKTEPGLLGKLIPGSSGKNGPVSSGTGAPGSLGRLDPTCLGMADPASVGNVETVPATKEDSRFLGKMDPASSGEGRPVSGHTDTTASAKTDLTSLKNVDPMSSGKVDPVSLGKMDPMCSGKPELLSPGQAERVSVGKAGTVSPGKEDPVSSRREDPISAGSRKTSSEKVNPESSGKTNPVSSGPGDPRSLGTAGPPSAVKAEPATGGKGDPLSSEKAGLVASGKAAPTASGKAEPLAVGKEDPVSKGKADAGPSGQGDSVSIGKVVSTPGKTVPVPSGKVDPVSLGKAEAIPEGKVGSLPLEKGSPVTTTKADPRASGKAQPQSGGKAETKLPGQEGAAAPGEAGAVCLKKETPQASEKVDPGSCRKAEPLASGKGEPVSLGKADSAPSRKTESPSLGKVVPLSLEKTKPSSSSRQLDRKALGSARSPEGARGSEGRVEPKAEPVSSTEASSLGQKDLEAAGAERSPCPEAAAPPPGPRTRDNFTKAPSWEASAPPPPREDAGTQAGAQACVSVAVSPMSPQDGAGGSAFSFQAAPRAPSPPSRRDAGLQVSLGAAETRSVATGPMTPQAAAPPAFPEVRVRPGSALAAAVAPPEPAEPVRDVSWDEKGMTWEVYGAAMEVEVLGMAIQKHLERQIEEHGRQGAPAPPPAARAGPGRSGSVRTAPPDGAAKRPPGLFRALLQSVRRPRCCSRAGPTAE
What is the function of this protein?
May be involved in neurite outgrowth.
What are the official names of this protein?
G protein-regulated inducer of neurite outgrowth 1, GRIN1.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Cell projection, growth cone. Note=Highly enriched in growth cone.
Protein: RIBBA_MYCTU
Sequence: MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRGHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGEFGGAL
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: ATPD_SYNFM
Sequence: MKNLIIAKRYSKALFNLAEEGRMIEQYGEELDNFVRLLGKLPELADALRNPLFPEATRKAIFAAVAEQLALTPIVRSFINLLIVKKRVEHLESIAQYYHRLIDEYSNVARAQVKAAIDLDEKVIQEIAKTLEKMTGKKIVVEFQKDPSLIGGVLAQIGDFVLDGSVKRQLLNFKETLKRGALG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: STS1_CANAL
Sequence: MMSTNFQWPGTNKNDNTEVSVETPSSTDPHVPRYPFTAMSHATASTTMKKRKRDDFDGDKSTTITMNTTTTRKYIQSSLGSSKFKKAKTPKISGQPLPLPRLIESLDKSNLQKLVQDLITVHPELQSTLIKISPRPSIQDSIQLLQDKFDMIISHLPYKCDVESDYSYLRIKPHLQEFLSSVSDFILNYLPPLETNMTHSLQFLHETTKLVYNLPNFTNQEFQYTKSSALEQIANCWLIVLSQDEEKEGNTDVVKVIQELELLEKLHEHNEISFNKFEKVVDYCKDKLEQHELIMNNNEAGSGVTSSISDLITVDYSKYSIANTTSI
What is the function of this protein?
Involved in ubiquitin-mediated protein degradation.  Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates.  Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).
What are the official names of this protein?
Tethering factor for nuclear proteasome STS1.
What is the protein family that this protein belongs to?
Belongs to the cut8/STS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RPOZ_ANASK
Sequence: MARVTVEDCLPMVDNRFALVLLATKRTRQLMAGARPLQAASKNKPPVLALREIATGKVRFDRSVRDALSGKFDKEKVNIPAGQTRTLR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: ACKA_STAAW
Sequence: MSKLILAINAGSSSLKFQLIRMPEEELVTKGLVERIGLKDSIFTIEVNGEKVKTVQDIKDHVEAVDIMLDAFKAHNIINDINDIDGTGHRVVHGGEKFPESVAITDEVEKEIEELSELAPLHNPANLMGIRAFRKLLPNIPHVAIFDTAFHQTMPEKAYLYSLPYHYYKDYGIRKYGFHGTSHKFVSQRAAEMLDKPIEDLRIISCHIGNGASIAAIDGGKSIDTSMGFTPLAGVTMGTRSGNIDPALIPFIMEKTGKTAEQVLEILNKESGLLGLSGTSSDLRDLSEEAESGKARSQMALDVFASKIHKYIGSYAARMHGVDVIVFTAGIGENSVEIRAKVLEGLEFMGVYWDPKKNENLLRGKEGFINYPHSPVKVVVIPTDEESMIARDVMTFGGLK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_STRMU
Sequence: MMGIRIAIDGPASSGKSTVAKIIAKKLGYVYLDTGAMYRSATYLALQNDTDLTDERAIVKLLKDYPISFGRRKDDSEQLVFVGNVEVSHPIRENEVTNNVSTVAALPLVRKTLVDLQQQLAKKGGIVMDGRDIGTVVLPDAELKIFLIASVEERAERRYRENLEKGIQTDFNTLKKEIAERDYKDSHRKISPLKPAADAITFDTTGIDIAGVVNFIEKKAQNIIDRS
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM258_DROME
Sequence: MDVMQRYVSPVNPAVFPHLATVLLVIGTFFTAWFFIFVVSRKSSKESTLIKELLISLCASIFLGFGIVFLLLTVGIYV
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity (By similarity).  In addition may regulates nuclear envelope (NE) architecture and nuclear positioning through the linker of nucleoskeleton and cytoskeleton (LINC)-dependent and -independent mechanisms (PubMed:28716842).
What are the official names of this protein?
Transmembrane protein 258, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TMEM258, Oligosaccharyl transferase subunit TMEM258, Protein kuduk, Transmembrane protein 258 homolog.
What is the protein family that this protein belongs to?
Belongs to the OST5 family.
What are the subcellular locations of this protein?
Nucleus outer membrane; Multi-pass membrane protein. Cytoplasm. Endoplasmic reticulum membrane.
Protein: S4A10_BOVIN
Sequence: MQSGTCESFQSLSHQRNDEEAVVDRGGTRSILKTHFEKEDLEGHRTLFIGVHVPLGGRKSHRRHRHRGHKHRKRDRERDSGLEDGRESPSFDTPSQRVQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRIPIVRSFADIGKKQSEPNSMDKNAGQVVSPQSAPACVENKNDVSRENSTVDFSKGLGGQQKGHTSPCGMKQRHEKGPPHQQDREVDLHFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAEPHGGHSGPELQRTGRLFGGLILDIKRKAPYFWSDFTDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHNPSNNTLKEWRESNISASDIIWENLTVSECTSLHGEYVGRACGHEHPYVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGWFVTPLGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTVIQMSCLGLLWIIKVSRAAIVFPMMVLALVFVRKLMDFLFTKRELSWLDDLMPESKKKKLEDAEKEEEQSMLAMEDEGTVQLPLEGHYRDDPSVINISDEMSKTALWRNLLITADNSKDKESSFPSKSSPS
What is the function of this protein?
Sodium/bicarbonate cotransporter which plays an important role in regulating intracellular pH (By similarity).  Has been shown to act as a sodium/bicarbonate cotransporter in exchange for intracellular chloride (By similarity).  Has also been shown to act as a sodium/biocarbonate cotransporter which does not couple net influx of bicarbonate to net efflux of chloride, with the observed chloride efflux being due to chloride self-exchange (By similarity).  Controls neuronal pH and may contribute to the secretion of cerebrospinal fluid (By similarity).  Reduces the excitability of CA1 pyramidal neurons and modulates short-term synaptic plasticity (By similarity).  Required in retinal cells to maintain normal pH which is necessary for normal vision (By similarity).  In the kidney, likely to mediate bicarbonate reclamation in the apical membrane of the proximal tubules (By similarity).
What are the official names of this protein?
Sodium-driven chloride bicarbonate exchanger, Solute carrier family 4 member 10.
What is the protein family that this protein belongs to?
Belongs to the anion exchanger (TC 2.A.31) family.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Cell projection, axon. Perikaryon. Presynapse. Postsynapse. Note=Detected in dendrites and axon terminals of retinal OFF bipolar cells and in axon terminals of ON bipolar cells. In amacrine cells, located in the perikaryon. Also detected in basal and apical dendrites of hippocampal pyramidal cells.
Protein: YAT2_YEAST
Sequence: MSSGSTIVSSDKSGRTFKHEEELPKLPLPKLCDTLQRLKESLEPLYYADGYYQHPLDPEQIEKLSSIIRDFEENPVSEKLQSKLQSYHDTRDCYLDELHLDINNQTSTREIQDDVLPRNPFLVLADDALPNITQADRSAVLVHSAARFISALKQDLLPPDINATNGKPLSMAPFLNLFGTTRSPVFQRGEVENFDLNKPYTASDLEDPDYSSDEDDNDEPTQKDFDDRKRKHEEDIFTGNGITIKRHPDSKHILIISRGQYYTLEVLDSTNKIIYTAAELTTIFNHIIKDSSGIEKSTALGSLTSHSFRNWKYARKRLQKRYPNELHRIDSALFVLVLDESQEETTNDGDDTADISQMFNRTITERDKKCTSANCKRVFYGTSIINSKGHQVGSCVSRWYDKLQLVVTADAKATVIWDSFTCDGSVVLRFTSEIYTESVLRLARDVNAGDPQFSLWPNVTQMDPETKKLMTATISADGGGPSEIDPKLVVNKIDWSFSNILNTHVHLSETKLADLISKYDIVRASIPLGRRSAQRLGVKPDSMVQVALQIAHYALYGRMVFGLEPVSTRGFKNSRSSFINIQSQALLELCQLFISSSIDGTDKLDKFIQTCETHNNMVKHAKSGVGYEKHFNALKYLFKFHDHFGIHLSGDESSAAKDLFENPLVLPFSQPELIVANCGNAATTTFGITPAVPHGFGIGYIIKDDQVDLTVTSQFRQGDRLMFMLSWVLGEIRSYWRMSRGTSHNKTGVKISPVVDKLYEMDNAVNNPPKRNGHTVNGSRKTSSSSQVNLNRYGGFFDLEGHIDSRNISKTPSMKNLQKTFNGLTMSADNDHSSSAVSVPTEKEKLNTGHEILQIQPREVASNGLEADDETDIEIVAGNADGTSSSASSATSLNSKKRNVINSRFDIDFDRSRVGRKVATLDQ
What is the function of this protein?
Carnitine O-acetyltransferase involved in the shutteling of acetyl-CoA in the cell.
What are the official names of this protein?
Carnitine O-acetyltransferase YAT2.
What is the protein family that this protein belongs to?
Belongs to the carnitine/choline acetyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_SHESR
Sequence: MRIGILGGTFDPIHYGHIRPAMEVKASLKLDKILLMPNHIPPHKNTTHSSTAQRLEMVAQVCEALTGFELCDIEAKRDSPSYTVVTLKQLSRLYPDDELFFIMGMDSFIHLQSWHKWQQLFELANIVVCQRPGWHLAEGHPMQHELNVRHATLEALSHSSAPQHGRIFTVDISPQDISSTQIRSLLAMGEIPQDALLPVTLNYIQKQRLYFS
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: ATXB_LEIDO
Sequence: MSSKKYELDAAAFEDKPESHSDAEMTPQKPQRRQSVLSKAVSEHDERATGPATDLLPPSKGLTTEEAEELLKKYGRNELPEKKTPSWLIYVRGLWGPMPAALWIAIIIEFALENWPDGAILFAIQIANATIGWYETIKAGDAVAALKNSLKPTATVYRDSKWQQIDAAVLVPGDLVKLASGSAVPADCSINEGVIDVDEAALTGESLPVTMGPEHMPKMGSNVVRGEVEGTVQYTGSLTFFGKTAALLQSVESDLGNIHVILRRVMLALCAISFILCMCCFIYLLARFYETFRHALQFAVVVLVVSIPIALEIVVTTTLAVGSKHLSKHKIIVTKLSAIEMMSGVNMLCSDKTGTLTLNKMEIQEQCFTFEEGNDLKSTLVLAALAAKWREPPRDALDTMVLGAADLDECDNYQQLNFVPFDPTTKRTAATLVDRRSGEKFDVTKGAPHVILQMVYNQDEINDEVVDIIDSLAARGVRCLSVAKTDQQGRWHMAGILTFLDPPRPDTKDTIRRSKEYGVDVKMITGDHLLIAKEMCRMLDLDPNILTADKLPQIKDANDLPEDLGEKYGDMMLSVGGFAQVFPEHKFMIVETLRQRGYTCAMTGDGVNDAPALKRADVGIAVHGATDAARAAADMVLTEPGLSVVVEAMLVSREVFQRMLSFLTYRISATLQLVCFFFIACFSLTPKAYGSVDPNFQFFHLPVLMFMLITLLNDGCLMTIGYDHVIPSERPQKWNLPVVFVSASILAAVACGSSLMLLWIGLEGYSSQYYENSWFHRLGLAQLPQGKLVTMMYLKISISDFLTLFSSRTGGHFFFYVPPSPILFCGAIISLLVSTMAASFWHKSRPDNVLTEGLAWGQTNAEKLLPLWVWIYCIVWWFVQDVVKVLAHICMDAVDLFGCVSDASGSGPIKPYSDDMKVNGFEPVKKPAEKSTEKALNLSVSSGPHKALEGLREDTHVLNESTSPVNAFSPKVKK
What are the official names of this protein?
Probable proton ATPase 1B, LdH1B.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MIAA_ACTP7
Sequence: MGPTASGKTDLAIALRQTLPVEVISVDSALIYKGMDIGTAKPSKAELELAPHRLIDILDPSESYSAMNFREDALREMAEITASGRIPLLVGGTMLYYKALLEGLSPLPSADPEIRAEIEAKAEQIGWSGLHRELLAIDPIAGKRINPNDSQRINRALEVFYITGKTMTELTAQQGDSLPYNVLQFAIAPQDRAVLHQRIEQRFYKMMELGFQQEVEKLRARSDLHKDLPSIRCVGYRQMWEYLDGDISLDEAIYKGICATRQLAKRQITWLRGWNSEITWLDSLDPTSSKLKMIEKIAQNSIKL
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: URED1_BRUSU
Sequence: MLIINDNNLSGLSLQRVNGTGELSVQFKDGRSRISRLYQEGAAKIRMPQAVTGPLEAILINTSGGLTGGDRLKWDVALDDGASAVITTQACERIYRSGGGEARIATRLKAAKGTRLAWLPQETILFNRSILSRRLDVELEEGAQMLVVEATVFGRLAMGERVVAARFADRWRVRLGGRVIHAEEFRLGPDVGAELQAPAVAGGACAMATVLMVCEQAGRHLETARAIIGEEGGCSLWRVGKASKLVVRLYAPDSYALRRRLCPLVALLNGKAGLPKVWTI
What is the function of this protein?
Disrupting the ure1 operon causes loss of urease activity, decreased resistance to low pH killing in vitro and decreased pathogen survival when inoculated in BALB/c mice by gavage.
What are the official names of this protein?
Urease accessory protein UreD 1.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CL38_CAEEL
Sequence: MAIFYDDPLERLNQPIKTKSYRKKQVVQRVHVFIFDNWKLILLGILNLIFLIIAIVFAILFFVGSADCAQLPDYTTSPASQLTTSAISSRTSEVQTNAITTTQGTPSNKTSTTTPSTSKVICASGFTLVGTKCGKLVSSNQPRTEADSICKGYGGSTLFSVRNEQETRDMLDFVKDSNIDFLWTGLVCNQTARTSCIWDVKSGTTADYNNFADGFPNVVYGYCIYFIVTGNSAGQWGSEQCSQLMNFVCELPTTIRDPDCKYNYNKNCYIRFDITLTIPQAQRFCNEKGADLVSIHSANENRFILTIYDIHGQILLGGLAPAVDFIVWLDGSPTTYSNLLYFYDTRSCVLMTVARGGPYDGDWYTMNCNVQEFFLCKRAIDF
What is the function of this protein?
Involved in negative modulation of unc-40-mediated axon outgrowth (PubMed:18434533).  Required for proper presynaptic development in axons that have reached their targets (PubMed:18434533).  May function in concert with E3 ubiquitin-protein ligase rpm-1 in regulating axon outgrowth (PubMed:18434533).
What are the official names of this protein?
C-type lectin domain-containing protein 38.