PharMolix/UniProtQA huggingface dataset:
Protein: UVRB_LEGPC
Sequence: MKDLFKIYSNYQPAGDQPTAIASLIDGLESGLAKQTLLGVTGSGKTFTIAHVIQAMKRPTLIMAPNKTLAAQLYGEFKAFFPDNAVEYFVSYYDYYQPEAYVPASDTFIEKDASINEHIEQMRLSATKALIERKDAIIVATVSAIYGLGDPDSYLRMLLHLSRGEQSDQRKILKRLAEMQYTRTNLSLERGQFRVHGDVIDIFPADSEKEAIRIELFDDEVDNIARFDPLTGEILQRLPRVTIFPKTHYVTPRERILETVEKVKAELQERLAELNAQNKLVEAQRLEQRTCFDIEMMLELGYCSGIENYSRYLSNREAGEAPPTLFDYLPPDALLIIDESHVTVPQIGGMYRGDRARKETLVNYGFRLPSALDNRPLRFEEFEERSPQTIYISATPGPYEQEHSDNVAEQVVRPTGLIDPEVEIRPVKTQVDDLMSEIRQVIAQGSRILVTTLTKRMAEDLTEYLSEHGIKVRYLHSDVDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVALVAILDADKEGFLRSERSLIQTIGRAARNVKGRAILYADTMTGSMQRALMETERRREKQKAFNLKHGITPKGINKSVEDILEGAYIGKRKTMVAEQAPRYTHWSPQELAKQINALEKQMYAHAQNMEFELAAKIRDEYLLLKEQLMKI
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADA_BACC3
Sequence: MSILEKVQPIETMLPERYYTMSTEDMEKRVREIKEKMGETLFIPGHHYQKDEVVQFSDAAGDSLQLAQVAASNKEAKYIVFCGVHFMAETADMLTTDEQVVILPDMRAGCSMADMADIEQTERAWKELTKLFGDTMIPLTYVNSTAAIKAFCGRNGGATVTSSNAKQMVSWAFTQKERLVFLPDQHLGRNTAYDLGIPLDKMAVWDPHTDSLEYDGDIEEIQVILWKGHCSVHQNFTVKNIENVRKNHPDMNIIVHPECCYEVVAASDYAGSTKYIIDMIELAPSGSKWAIGTEMNLVNRIIQQHPDKEIVSLNPFMCPCLTMNRIDLPHLLWALETIERGEEINVISVDKQVTEEAVLALNRMLERV
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRBP1_CRIGR
Sequence: MDELPFGEAAVEQALDELGELDAALLTDIQDMLQLINNQDSDFPGLFDSPYAGGGAGDTEPTSPGANSPESLSSPASLGSSLEAFLGEPKATPASLSPVPSASTALKMYPSVPPFSPGPGIKEEPVPLTILQPPAAQPSPGTLLPPSFPPPPLQLSPAPVLGYSSLPSGFSGTLPGNTQQPPSSLSLASAPGVSPISLHTQVQSSASQQPLPASTAPRTTTVTSQIQRVPVVLQPHFIKADSLLLTTVKTDTGATMKTAGISTLAPGTAVQAGPLQTLVSGGTILATVPLVVDTDKLPIHRLAAGSKALGSAQSRGEKRTAHNAIEKRYRSSINDKIVELKDLVVGTEAKLNKSAVLRKAIDYIRFLQHSNQKLKQENLALRNAAHKSKSLKDLVSACGSAGGTDVAMEGVKPEVVDTLTPPPSDAGSPSQSSPLSLGSRGSSSGGSDSEPDSPVFEDSQVKAQRLHSHGMLDRSRLALCALVFLCLTCNPLASLFGWGIPGPSSASGAHHSSGRSMLEAESRDGSNWTQWLLPPLVWLANGLLVLACLALLFVYGEPVTRPHTSPAVHFWRHRKQADLDLARGDFAQAAQQLWLALQALGRPLPTSNLDLACSLLWNLIRHLLQRLWVGRWLAGRAGGLRRDCGLRMDARASARDAALVYHKLHQLHAMGKYTGGHLIASNLALSALNLAECAGDAVSMATLAEIYVAAALRVKTSLPRALHFLTRFFLSSARQACLAQSGSVPLAMQWLCHPVGHRFFVDGDWAVHGAPQESLYSVAGNPVDPLAQVTRLFCEHLLERALNCIAQPSPGTADGDREFSDALGYLQLLNRCSDAVGTPACSFSVSSSMASTTGTDPVAKWWASLTAVVIHWLRRDEEAAERLYPLVERMPHVLQETERPLPKAALYSFKAARALLDHRKVESGPASLAICEKASGYLRDSLAAPPTGSSIDKAMQLLLCDLLLVARTSMWQRQQSPASAQVAHSASNGSQASALELRGFQQDLSSLRRLAQNFRPAMRRVFLHEATARLMAGASPARTHQLLDRSLRRRAGSSGKGGTVAELEPRPTWREHTEALLLASCYLPPAFLSAPGQQMSMLAEAARTVEKLGDHRLLLDCQQMLLRLGGGTTVTSS
What is the function of this protein?
Key transcription factor that regulates expression of genes involved in cholesterol biosynthesis and lipid homeostasis.  Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3').  Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3').  Regulates the promoters of genes involved in cholesterol biosynthesis and the LDL receptor (LDLR) pathway of sterol regulation.
What are the official names of this protein?
Sterol regulatory element-binding protein 1, SREBP-1, Sterol regulatory element-binding transcription factor 1.
What is the protein family that this protein belongs to?
Belongs to the SREBP family.
What are the subcellular locations of this protein?
[Sterol regulatory element-binding protein 1]: Endoplasmic reticulum membrane; Multi- pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein. Note=At high sterol concentrations, the SCAP-SREBP is retained in the endoplasmic reticulum. Low sterol concentrations promote recruitment into COPII-coated vesicles and transport of the SCAP-SREBP to the Golgi, where it is processed. SUBCELLULAR LOCATION: [Processed sterol regulatory element-binding protein 1]: Nucleus.
Protein: RRP6_SCHPO
Sequence: MDESELFKGLMNSTAYCSELAKVDIPFYKSIDTEFNENIKSVSSRFMRLIELLLSKVDRSRAEDIVDVEDIDNRWAEVSDTLDILFEKADYSIDKAQGLLKKPAIETHASTSDVANKKPKKEKLPYKVIHAAHLTKPQLRFRVQPNNSREFVWSWKLTEKPHSLVPLEKIIAQVKLDPSLKNSLPHPYEPEIQNSVYPPWVSEMSNPIDTGSVDETEPIWVSTESQLSDMLKELQNSKEIAVDLEHHDYRSFRGFVCLMQISNREKDWIVDTLELREELEALNVVFTNPNIIKVFHGATMDIIWLQRDFGLYVVNLFDTYYATKVLGFEGHGLAFLLQKYCDYDADKRYQMADWRIRPLPREMLKYAQSDTHYLLYIWDHLRNELISKSAERKENLMQSVFNSSKQISLRKYELEPYDPIYGLGTDGWRNVLTKFGSSKIIGREALMIYRALHDWRDSVARKEDESVRYVLPNRLLIAIAASKPVEAADVFSISKQLTPIARMYVEDIVKVVQEAEKLYNEQVDREKSQFKEVEKQNQPLAVFSESNTLGDYKVDSSVFEISKQNRSKLKTLLANGSAFWIEGQSQDDLRKARKERLFIVNQNIPFSLTLPCTQGHVESELNVKQSTVTEAANPSLNGEKKQEPIVIRDLGLNKQKRDSSKLNHKEPSNPIEERNEDIEPSEASTSVSKKRKQKKKKKNSGKLTIEAEHVSNDSPIINEAPFDYKNQKNFIADLDSDVGKNKFGKRGFNPLNKVSLPKRNTRELKKRKVSDGKSTSY
What is the function of this protein?
Nuclear-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.  In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm.  The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.  RRP6 has 3'-5' exonuclease activity which is not modulated upon association with Exo-9 suggesting that the complex inner RNA-binding path is not used to access its active site (By similarity).
What are the official names of this protein?
Exosome complex exonuclease rrp6, Ribosomal RNA-processing protein 6.
What is the protein family that this protein belongs to?
Belongs to the exosome component 10/RRP6 family.
Protein: YCGR_NITEC
Sequence: MAILQTFSEQTISSARASDIKEPDYSVNSRPEICFFLNGIMEEKSLISLYLARDSHSAILSSILAVDPQQKLLIMDYGINETLNQIALKRGYLRCITSHNQIRIEFDCDNLQRVQFEGRHAFSADIPESLKRLQRRNFYRVTTSITNPAVCTIPLLRAADEAPVVYSLLDISCGGMALIDQPDADTLLKAGTTLEHCRIDLPGDGNLFSSIEASIQIAYVGTVILNNGNTCPRIGCEFINLPEKSRLLIQRYITKLEQQARKLETESGF
What is the function of this protein?
Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner.  Binds 1 c-di-GMP dimer per subunit.  Increasing levels of c-di-GMP lead to decreased motility.
What are the official names of this protein?
Flagellar brake protein YcgR, Cyclic di-GMP binding protein YcgR.
What is the protein family that this protein belongs to?
Belongs to the YcgR family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: TAF13_PONAB
Sequence: MADEEEDPTFEEENEEIGGGAEGGQGKRKRLFSKELRCMMYGFGDDQNPYTESVDILEDLVIEFITEMTHKAMSIGRQGRVQVEDIVFLIRKDPRKFARVKDLLTMNEELKRARKAFDEANYGS
What is the function of this protein?
The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription.  TFIID recognizes and binds promoters via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC).  The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13.  TAF13, together with TAF11 and TBP, play key roles during promoter binding by the TFIID and TFIIA transcription factor complexes.
What are the official names of this protein?
Transcription initiation factor TFIID subunit 13, Transcription initiation factor TFIID 18 kDa subunit, TAF(II)18, TAFII-18, TAFII18.
What is the protein family that this protein belongs to?
Belongs to the TAF13 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL14_PYRIL
Sequence: MAKRGGKRTVGVSYRFHVTPGIFLNSLVPVADNSGARLVRVIGVVGHYSKTVHRRIPGAGVGDMVVVVVREGKPELRKQIFRAIVVRQRRPYRRPDGTWVAFEDNAVVIVTPEGDPKGSEIHGPVAMEATLRWPTIANLASIIV
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: CEPU1_CHICK
Sequence: MAQAKMQHPVSWVIFAGMAALLLFQGVPVRSGDATFPKAMDNVTVRQGESATLRCSVDNRVTRVAWLNRSSILYAGNDKWCLDPRVVLLANTKTQYSIQIHDVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVSPKITETSSDISINEGGNVSLTCIATGRPDPTITWRHISPKAVGFISEDEYLEITGITREQSGEYECSASNDVAAPVVQRVKVTVNYPPYISDAKSTGVPVGQKGILMCEASAVPSADFQWYKDDKRLAEGQKGLKVENKAFFSRLTFFNVSEQDYGNYTCVASNQLGNTNASMILYEETTTALTPWKGPGAVHDGNSGAWRRGSCAWLLALPLAQLARQF
What is the function of this protein?
It may be a cellular address molecule specific to Purkinje cells.  It may represent a receptor or a subunit of a receptor complex.
What are the official names of this protein?
Protein CEPU-1.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. IgLON family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: YDIV_ECOLI
Sequence: MKIFLENLYHSDCYFLPIRDNQQVLVGVELITHFSSEDGTVRIPTSRVIAQLTEEQHWQLFSEQLELLKSCQHFFIQHKLFAWLNLTPQVATLLLERDNYAGELLKYPFIELLINENYPHLNEGKDNRGLLSLSQVYPLVLGNLGAGNSTMKAVFDGLFTRVMLDKSFIQQQITHRSFEPFIRAIQAQISPCCNCIIAGGIDTAEILAQITPFDFHALQGCLWPAVPINQITTLVQR
What is the function of this protein?
Upon overexpression acts as a novel anti-FlhC(2)FlhD(4) factor, decreasing its DNA-binding activity, able to negatively regulate expression of flagellar class II operons including FliC.
What are the official names of this protein?
Putative anti-FlhC(2)FlhD(4) factor YdiV, c-di-GMP regulator CdgR.
What is the protein family that this protein belongs to?
Belongs to the YdiV family.
Protein: PSB1_SULTO
Sequence: MEELPATALGIKLNDGIILAAERRLSYGGFVLSRSAKKVFKIGRFGIAGAGIMGDIQTLTRLMNVEIKYYEMYNNKPISVKAAAKLLSVILYQYKWTPFISELLFGGVDDEGPKLFVLDPIGSLIEDNYAAVGSGARVAIGVLESEYDPSMNLDKGKEIVLKALKAAIERDVTSGDGIDILTIKRDNTSSEDFIKIF
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta 1, 20S proteasome beta subunit 1, Proteasome core protein PsmB 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAE_BORBU
Sequence: MGRNPLIIGVTGRIASGKDTVSKIISNKYGFYEINADKLGHSVLHEKKEEIVKIFGQKILNTKNEIDKLLLRNLVFNDNKELKKLESVSHPVILSKIKKILIQNQSTKIIINAALLFKMNLEKLCDYIIVLKAKNSIIKNRLSYSIPNIDSNMINKILKIQKDIFFEKNIINLKIINIINNKNYAYLEKEIEKKMQGIINYERFE
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUSA_PSEAE
Sequence: MRPEPTNAPAALSRRFSVAPMMDWTDRHCRFFLRQLSRHTLLYTEMVTTGALLHGDRQRFLRYDECEHPLALQLGGSVPAELAACARLAEEAGYDEVNLNVGCPSDRVQHNMIGACLMGHPALVADCVKAMLDAVEIAVTVKHRIGINGRDSYAELCDFVGQVREAGCRSFTVHARIAILEGLSPKENREVPPLRYEVAAQLKKDFPDLEIVLNGGIKTLEACREHLQTFDGVMLGREAYHNPYLLAAVDSQLFGSEAPPLSRSEALLRLRPYIERHQAEGGAMHHVTRHILGLAQGFPGSRRFRQLLSVDVHKAADPLRVFDQALELLAGR
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.  Specifically modifies U20 and U20a in tRNAs.
What are the official names of this protein?
tRNA-dihydrouridine(20/20a) synthase, U20-specific dihydrouridine synthase, U20-specific Dus, tRNA-dihydrouridine synthase A.
What is the protein family that this protein belongs to?
Belongs to the Dus family. DusA subfamily.
Protein: VE6_HPV56
Sequence: MEPQFNNPQERPRSLHHLSEVLEIPLIDLRLSCVYCKKELTRAEVYNFACTELKLVYRDDFPYAVCRVCLLFYSKVRKYRYYDYSVYGATLESITKKQLCDLLIRCYRCQSPLTPEEKQLHCDRKRRFHLIAHGWTGSCLGCWRQTSREPRESTV
What is the function of this protein?
Plays a major role in the induction and maintenance of cellular transformation.  E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase and modulates its activity.  Sequesters tumor suppressor TP53 in the host cytoplasm and modulates its activity by interacting with host EP300 that results in the reduction of TP53 acetylation and activation.  In turn, apoptosis induced by DNA damage is inhibited.  E6 protects also host keratinocytes from apoptosis by mediating the degradation of host BAK1.  May also inhibit host immune response.
What are the official names of this protein?
Protein E6.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E6 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: SYA_BORBR
Sequence: MKSSEIRQKFLQFFQSKGHTIVPSSSLVPANDPTLLFTNSGMVQFKDVFTGKEARAYKRATSSQRSVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKREAIQYAWELLTQVYRLPAEKLWVTVYQEDDEAYDIWAKEVGVPAERIIRIGDNKGARYASDNFWQMADTGPCGPCSEIFYDHGPEIWGGPPGSPEEDGDRYIEIWNLVFMQFERDAAGNMERLPKPCVDTGMGLERIAAVLQHVHSNYEIDLFQKLIAAAARETGVKDLADNSLKVIADHIRACAFLIVDGIIPSNEGRGYVLRRIVRRALRHGYKLGQTKPFFHRLVPDLVAEMGEAYPELAQVAERVAQVLRQEEERFGETLEHGMKILDGALAKVAKGDPLDGTTLFTLYDTYGFPVDLTADICRERGVEVDMAGFEAAMQRQREQARAAGKFKMAEGLSYEGAETRFEGYESLELSGVKVTALYVEGTQVEQVSAGQDAVVVLDATPFYAESGGQVGDTGLLEAGGVRFAVADTLKIQPGVFGHHGTLEAGALKVGDTLLARVDAVRRARTVRNHSATHLMHKALREVLGAHVQQRGSLVDPDKTRFDFAHDAPMTAEQIARVEAIVNAEVLANQATEAKVMAYDDAVKGGAMALFGEKYGDTVRVLDIGFSRELCGGTHVRRTGDIGLFKVVSEGGVAAGVRRIEAITGDNALAWVQDQNALLQRAAGVLRAPAHELPERIVQVQEQLKALEKELEQARTKLAASAGNDLAATATVEVKGIKVLAASIGDVDPKALRGMVDNLKDRLKPAVVLLAAGSADGKISLVGGVTADLTGRIKAGDLVGFVAGQVGGKGGGRPDMAMGGGTDLAALPAAVASVQKWVDERL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSB_FRATT
Sequence: MDIKSNSFFYIFISVVLLLIAILQYDLWFSNTGFIKYQALKKSVISQQKEVKHKSQTNVQLYSEVVSLRQNSEVLESLARENMGLIKQGEVFYSVK
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: ILVC_RIPO1
Sequence: MARMYYDTDANLDLLAGKTIAIIGYGSQGHAHALNLKDSGINVIVGLYPGSKSAKKAEEAGLKVLSVAEAAQAADWIMILLPDEVQKAVYTHEIAPYLSEGKVLCFAHGFNIHFGQVVPPPTVDVVMIAPKGPGHLVRRTYEQGEGVPCLFAVYQDATGQARDRAMAYAKGIGGTRAGILETTFREETETDLFGEQVVLCGGLSALIKGGFETLVNAGYQPELAYFECLHEVKLIVDLIVEGGLAKMRDSISNTAEYGDLTRGPRIVTDETRAEMKKILREIQTGQFAREFVLENQSGKPGFTAMRRQEAEHPIEEVGKDLRAMFSWLKDK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: SYS_BIFAA
Sequence: MLDIQFIREHADVVKESQRKRGESVELVDEVLRSDEVRRSSLKEFEAARAQQKEIGKKVAAAPADEKAKLIAATKELSQKVSEYKAAADAAAEEYTTAMWKLSNIVEPEAPEGGEDDYVVVKKVGQIRDFAAEGFEPKDHLTLGRGVAGIDMERGVKVGGSRFYFLRGQVARMQIAMLTMAVDQAEEHGFTLAITPTLVRPEVMRGTGFLNSHADEIYRLREPDDQYLVGTSEVALAGMHENEILNLENGPLRYCGWSSCYRREAGAAGKDTSGIIRVHQFDKVEMFVYAKQEDSYKEHEHLLAMEQEMLGKVEVPYRIIDTAAGDLGSSAARKFDCEAWVPTQGRYRELTSTSNCTEYQARRLNIRERMEDGNTRAVSTLNGTLATTRWLVAILENHQQKDGSIEIPKAMRPYMGGKEVIEPTKWEA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMOA_ECOSE
Sequence: MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPGTQVYDLGCSLGAATLSVRRNIHHDNCKIIAIDNSPAMIERCRRHIDAYKAPTPVDVIEGDIRDIAIENASMVVLNFTLQFLEPSERQALLDKIYQGLNPGGALVLSEKFSFEDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARLHKAGFEHSELWFQCFNFGSLVALKAEDAA
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: CSM3_CANGA
Sequence: MDEDDMLMLGVGAEPTQHAEIEDPLTGGVASDPTMINDDPTAVNAKVRRPQVKLTAERLLSPNGLPYVMKHAPKRVRISKSRSTYKNLEHIIQFYQLWAHELFPKAKFKDFVRLCNSLGKTDADLRNYRTELFRADMENQFGDGYRSDKQNPANNSQPVTSTQLPNNDANSNDENNNVENDTNQLITGGQETTRHLFARDEEDDDDSDLYRSVPPPSSIAHESATSNTHAVPTSDTTLPISDNNPKGVTNSDGTVIGISEEDELLAMEEELNNYATQKIEELGDDKDTGIDPGEEEDEDALDAMKELGF
What is the function of this protein?
Forms a fork protection complex (FPC) with TOF1 and which is required for chromosome segregation during meiosis and DNA damage repair.  FPC coordinates leading and lagging strand synthesis and moves with the replication fork.  FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors (By similarity).
What are the official names of this protein?
Chromosome segregation in meiosis protein 3.
What is the protein family that this protein belongs to?
Belongs to the CSM3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RHAM_PECCP
Sequence: MLRKAFVMSVFPDCHDDYQRRHNPIWPELAEVLKNHGAHHYSIFLDKQRNLLFGYVEVESEARWEAIAQTEVCQRWWKYMSDVMPSNPDNSPVSEALEPVFYLD
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CASP_MOUSE
Sequence: MAANVGSMSQYWKRFDLQQLQRELDAAATVLANRQDESEQSRKRLIEQSREFKKNTPEDLRKQVAPLLKSFQGEIDALSKRSKEAEAAFLTVYKRLIDVPDPVPALDVGQQLEIKVQRLHDIETENQKLRETLEEYNKEFAEVKNQEVTIKALKEKIREYEQTLKSQAETIALEKEQKLQNDFAEKERKLQETQMSTTSKLEEAEHKLQTLQTALEKTRTELFDLKTKYDEETTAKADEIEMIMTDLERANQRAEVAQREAETLREQLSSANHSLQLASQIQKAPDVEQAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLNAKNSTLKQLEEKLKGQADYEEVKKELNTLKSMEFAPSEGAGTQDSTKPLEVLLLEKNRSLQSENATLRISNSDLSGRCAELQIHLTEATAKAVEQKELIARLEQDLSTIQSIQRPDAEGASEQGLEKIPEPIKEATALFYGPSMSSSGTLPEGQVDSLLSIISSQRERFRTRNQELEAESRMAQHTIQALQSELDSLRADNIKLFEKIKFLQSYPGRGIGSDDTELRYSSQYEERLDPFSSFSKRERQRKYLGLSPWDKATLGMGRLILSNKTARTIGFFYTLFLHCLVFLVLYKLAWSESVERDCAATCAKKFADHLHKFHESDNGAAAGDLWQ
What is the function of this protein?
May be involved in intra-Golgi retrograde transport.
What are the official names of this protein?
Protein CASP.
What is the protein family that this protein belongs to?
Belongs to the CASP family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type IV membrane protein.
Protein: LST4_VANPO
Sequence: MLANLFGKNGLNGSTASLSDSDSGSSSQYNSKPSSQYGSPTSINFKDDTSSILRPISGNILDHMSDDLKSKLFATKDLISDISLAYYDPKSTNSNINISPDSFRLLLTEETGQMVCRNNYRVVLDYVTPKGSYIEQIRPSELKEYIFGSPVRSSDSLEVDKIRVIPNSNILIISRTFHVSSKINRLAICLCLPSYYLPVVMEAWRQVSTWLDNTQASIISIISRLKKPPSTLHLQCDKELSCLLPADARFQFVSEFESIILALQRKIVPCLRSISEIPRLFLYPTTLMKFVELWFKDVFNWMELKDGPRMNFLSTLLAIIIVNFKEELKSSESTRIAIMSGNMVVSNKLINIISGILEPKYKGPLLHTDEDNELSTKLEQLDSIDTVNTSSTEIHMIKKTNSNSSISVSPASTKYQNSNKGWEIPRRRSAHSVASISSGESLAEVIQPSSLKSGSNSLHQLYASLSNNYGTSYGSWFNKRPNISQFMQYSSPSNSNESWDRAASIHRTNSGNSIQQLRAGFGITPQQSPSISEYDEYPWFGTPNSPHVENSATATTSNTTVSSASVPWTTKSITEPNRMYNVHIERDFQRISQTELLDDAFDKICKPGRKLECGLTVTPGNMIHAGVLEIEILNQDCVEKSSELLPRYTSYLRNYNSWFKLQAFPANNESESKVITSMKKDLSVYSYSKALLISLSTRDIKEVTIKKEYKNNTQDTNSFKLIQKTARMFHNGKPQANLSLELNNCILLIESTLKRASELLKPIQSSADTSTAMTQEARQEELLKLFKSIIYFKDTKT
What is the function of this protein?
Involved in extracellular amino acid uptake.  Required for the protein trafficking from the Golgi to the plasma membrane (By similarity).
What are the official names of this protein?
Protein LST4.
What is the protein family that this protein belongs to?
Belongs to the LST4 family.
Protein: PTH_THEVO
Sequence: MVVKLVVAVRKDLDMGKGKIAAQVAHAAVSCAIKAMKEKKKIFDEWMDEGQKKIVVKVPNVDEIYIIKKKADSMGIINEVIQDRGYTQVEPGTVTCIGLGPDYEVYLDDITGKYKLL
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH2 family.
What are the subcellular locations of this protein?
Cytoplasm.