PharMolix/UniProtQA huggingface dataset:
Protein: ARIP4_XENTR
Sequence: MSDASISGSEPELDPEDMEEEEEDDEDDDEEEEEEEDEEDNDGDDEDDKQDINEKSQNAALGEDSPEQGEEGWKRSTTSGQSGQESDEAKKKRLQKPANLRRNIRKLLREDQLESVTKTAQQEELERRKRLEQQRKDYPLPLTLPPVSLDFLQEEIELRAADVSQLVKSQEIICLDSSSGESDDEGKVKSHSIKDEIIELSSGEEDNLQISDNADSTNEVDGDITTENSGSHVNDALNQADHLGRVLVNINHPPNEKDIFLAPQLARAVKSHQIGGIRFLYDNLVESLERFSGSSGFGCILAHSMGLGKTLQVISFLDVLFQHTSAKTVLAIVPVNTLQNWLAEFNMWLPPPESLPKDHNQELVQPRAFKVHTMNDEHKTTAARAKVVNDWATDGGVLLMGYEMYRLLSLKKSFTAGRKKKSKKAAGPVIIDLDEEDRQQEMLKGIEKALSRPGPDVVICDEGHRIKNCHASTSQALKNIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCVDSTPQDKRLMRYRSHVLHSLLEGFVQRRGHTVLKAQLPFKEEHVILVRLSKIQRDLYTEFMNRFRDAGNSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKENLANEQDLDVEDLGTNNRCNAQSGKIKVEPNSLGALMGETAHTKQLQGIVLNPSHEKANQVVTYEWAKEILSDYIPGQLQNSPKMVLLFHLIEESMRMGDKILVFSQSLSTLSIMEEFLAKRKMPIPAGSDGQEGHTWIRNVNYYRLDGSTSASERERLINQFNDPSNEKVWLFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQRKPCYIYRLVSDFTLEKKIYDRQITKQGMSDRVVDDLNPEVNFTRREVENLLHFVEEEPDASRQHLDSSSFHEAVLQKACLQYPHLITKEPFQHESLLLDRKEQKLTLAEKKAAKRGYEEEKRASVPYTRPSYTQYYPAPDHNLGNIPAFSQRHWRPLMKGDDRPVASVRPLQSTPIPMLPRHVSVNHPGSASASVHPYNFPVNYLQRAGVLVQKVVTTTDIVIPGMTTSTDVQARISAGESIHVIRGTKGTYIRTSDGRIFAIRASGKQKSGEVRRQATSGAQGSSAPYLSNGRHSTSSPSQQDSEDPPRPLSPDSPEILNELQKYADAAAARGSHTAPQLQNLGLHHQGINPAPKLQPRKRKDPQDQSSHWPSNKRNPYSQLSYPNTGGFGVTPSTMNHNLVRSSNPVFMGPGGGSSHFQLPSLLSDPQTGLPLVQDSLLTHSSGTSSAPSVPPHYLLPRGFPLPFSQSLLPQTRMFAPYPSQILNRGLPTNNPASTFPGYLSSHSNYQASPGTSSRPLPSGETELGSCEEDGRDDDVVEVTGE
What is the function of this protein?
DNA helicase that modulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner.
What are the official names of this protein?
Helicase ARIP4, Androgen receptor-interacting protein 4, RAD54-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARGJ_GEOSE
Sequence: MTITKQTGQVTAVADGTVVTPEGFQAAGVNAGLRYSKNDLGVILCDVPASAAAVYTQSHFQAAPLKVTQASLAVEQKLQAVIVNRPCANACTGAQGLKDAYEMRELCAKQFGLALHHVAVASTGVIGEYLPMEKIRAGIKQLVPGVTMADAEAFQTAILTTDTVMKRACYQTTIDGKTVTVGGAAKGSGMIHPNMATMLAFITTDANVSSPVLHAALRSITDVSFNQITVDGDTSTNDMVVVMASGLAGNDELTPDHPDWENFYEALRKTCEDLAKQIAKDGEGATKLIEVRVRGAKTDEEAKKIAKQIVGSNLVKTAVYGADANWGRIIGAIGYSDAEVNPDNVDVAIGPMVMLKGSEPQPFSEEEAAAYLQQETVVIEVDLHIGDGVGVAWGCDLTYDYVKINASYRT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPG_BORBU
Sequence: MKKQFDTEVNDLLYLIIHSLYSHKEIFLRELISNASDAIDKLKFLSLTNEKFKNIALEPKIEISFDDKSILIKDNGIGMDEQDLTNHLGVIAKSGTKEFINNLKQDEKKSASLIGQFGVGFYSAFIVSEKVEVTSKKALESDAYIWSSDGKTGYEIEKAKKEESGTEIKLYLNKEGLEYANKWKIQEIIKKYSNHINYPIYIKYSEPIMKDGKQEGIEEKEEKLNETTALWTKNKSEIKAEEYNEFYKNTTFDYENPLMHIHTKAEGNLEYTNLFYVPSKAPYDLYYPNTKPGVKLFINRIFITDSEGSLLPNYLRFIKGIIDCQDLPLNVSREILQQNKILSKIKSSSVKKILSELEKLSKKNPEKFSEFSKEFGRCIKEGVYSDFENREKLISLIRFKSSSVDGFVSFKEYKERMNESQKSIYYITGGKENILKENPIVAAYKEKGFEILIMDDELDEAILNLIPEYEGLKLKAINKNETSNELKDENFKKIEEEFKDTLTKVKEILKDHIKEVNLSATLIKEPSAIIIDSNDPTYQMQKIMLSMGQEVKEIKPILELNPNNKIVQNLKNLEPEKLEKISILLFEEAMLTSGMPSKNPGKFINIINEFIEKDFL
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPPA_BACSU
Sequence: MKLYMSVDMEGISGLPDDTFVDSGKRNYERGRLIMTEEANYCIAEAFNSGCTEVLVNDSHSKMNNLMVEKLHPEADLISGDVKPFSMVEGLDDTFRGALFLGYHARASTPGVMSHSMIFGVRHFYINDRPVGELGLNAYVAGYYDVPVLMVAGDDRAAKEAEELIPNVTTAAVKQTISRSAVKCLSPAKAGRLLTEKTAFALQNKDKVKPLTPPDRPVLSIEFANYGQAEWANLMPGTEIKTGTTTVQFQAKDMLEAYQAMLVMTELAMRTSFC
What is the function of this protein?
Hydrolyzes N-terminal residues in D-amino acid containing peptides.  Among the tested substrates, the highest activities are with D-Ala-D-Ala and D-Ala-Gly-Gly.  The physiological role is not clear.
What are the official names of this protein?
D-aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M55 family.
Protein: TATB_PSYA2
Sequence: MFDIGFSELLLFGVIALIVLGPEKLPQAARTAGQWYAKIRRTVSTLQSEIEAELDLAETRQLMQKELAKIRQTEAEMRREMAEMRGSIKEFEHSQSQNLKTSDKAASPANQANNDSAIQNNNEPATFSYAYGQSNNLTDSQQLSNQDITSINSDAVTDSSTIKQPAQPLITKPWENMWFRLGAYDKARRLPAVPYLPNYKADILLNSSFDSSFDSPLNTQASVNQQESE
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PA2HB_AGKPI
Sequence: SVLELGKMILQETGKNAITSYGSYGCNCGWGHRGQPKDATDRCCFVHKCCYKKLTDCNHKTDRYSYSWKNKAIICEEKNPCLKEMCECDKAVAICLRENLDTYNKKYKAYFKLKCKKPDTC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that lacks enzymatic activity (PubMed:1429612, PubMed:28633930).  Displays edema-inducing activities (PubMed:1429612).  Is myotoxic (By similarity).  A model of myotoxic mechanism has been proposed: an apo Lys49-PLA2 is activated by the entrance of a hydrophobic molecule (e. g.  fatty acid) at the hydrophobic channel of the protein leading to a reorientation of a monomer (By similarity).  This reorientation causes a transition between 'inactive' to 'active' states, causing alignment of C-terminal and membrane-docking sites (MDoS) side-by-side and putting the membrane-disruption sites (MDiS) in the same plane, exposed to solvent and in a symmetric position for both monomers (By similarity).  The MDoS region stabilizes the toxin on membrane by the interaction of charged residues with phospholipid head groups (By similarity).  Subsequently, the MDiS region destabilizes the membrane with penetration of hydrophobic residues (By similarity).  This insertion causes a disorganization of the membrane, allowing an uncontrolled influx of ions (i. e.  calcium and sodium), and eventually triggering irreversible intracellular alterations and cell death (By similarity).
What are the official names of this protein?
Basic phospholipase A2 homolog AppP2, svPLA2 homolog, APP-K49.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. K49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NEUFC_HUMAN
Sequence: MLRCGGRGLLLGLAVAAAAVMAARLMGWWGPRAGFRLFIPEELSRYRGGPGDPGLYLALLGRVYDVSSGRRHYEPGSHYSGFAGRDASRAFVTGDCSEAGLVDDVSDLSAAEMLTLHNWLSFYEKNYVCVGRVTGRFYGEDGLPTPALTQVEAAITRGLEANKLQLQEKQTFPPCNAEWSSARGSRLWCSQKSGGVSRDWIGVPRKLYKPGAKEPRCVCVRTTGPPSGQMPDNPPHRNRGDLDHPNLAEYTGCPPLAITCSFPL
What is the function of this protein?
Heme-binding protein which promotes neuronal but not astrocyte differentiation.
What are the official names of this protein?
Neuferricin, Cytochrome b5 domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family. MAPR subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ILVD_VIBCH
Sequence: MPKYRSATTTHGRNMAGARALWRATGVKEEDFGKPIIAVVNSFTQFVPGHVHLKDLGQLVAREIEAAGGIAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMAAMRLNIPAIFVSGGPMEAGKTKLSDQIIKLDLVDAMMQGADPKVSDAQSEQIERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLTAGQRIVELTKRYYEQDDASVLPRNIANKAAFENAIALDIAMGGSTNTVLHLLAAAQEGEVEFDMTDIDRMSRQVPHLCKVAPSTQKYHMEDVHRAGGVMGILGELQRAGLLKDQTRTVLGISLQEQLAQYDVKQTQDPAVHTMFRAGPAGIRTTQAFSQDCRWDTLDDDRQEGCIRDKAHAFSQDGGLAVLKGNLAIDGCIVKTAGVDESILKFRGPAVVYESQEDAVNGILGGQVKAGDVVVIRYEGPKGGPGMQEMLYPTTYLKSMGLGKQCALLTDGRFSGGTSGLSIGHASPEAANGGTIGLVRSGDSIAIDIPNRSITLEVSESELAARRAEQDKLGWKPVDRQRTVSLALKAYASMATSADKGAVRDKSKLEG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RBL_HALHL
Sequence: MASKTYTAGVKDYRETYWEPDYKIKDSDLLAVFKVTPQPGVDREEAAAAVAAESSTGTWTTVWTDLLTDLEHYKGRAYKVEDVPGDDEAFYAFIAYPIDLFEEGSIVNVFTSLVGNVFGFKAVRALRLEDVRFPLHFVMTCPGPPNGIQVERDKMNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFEFVMEAIQKAEEETGERKGHYLNVTAPTPEEMYKRAEFAKELGAPIIMHDYITAGFCAHQGLANWCRDNGMLLHIHRAMHAVLDRNPNHGIHFRVLTKILRLMGGDQLHTGTVVGKLEGDRQSTLGWIDLLRKPYIEEDRSRGLFFDQDWGAMPGAFAVASGGIHVWHMPALLSIFGDDAVFQFGGGTLGHPWGNAAGAAANRVALEACVKARNEGRELEKEGKEILTEAAKSSPELKAAMETWKEIKFEFDTVDKLDTAHR
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
Protein: RL7_BUCAP
Sequence: MSITKEQILEAVSEMSVMNVVELISAMEKKFGVSANMSVNTNNNSEKSTIEEKTEFDIFLKSIGPNKVSVIKSVRSATGLGLKEAKDLVESAPTVLKENMSKNDAESLKKTLEDAGAEIEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: DXS_XANP2
Sequence: MTLLKTPLLDTIRDAADVRRLPQDKLAQLAAELRAETIDAVSVTGGHLGAGLGVVELTVALHHVFNTPHDRLIWDVGHQCYPHKILTGRRDRIRTLRQGGGLSGFTRRAESEYDPFGAAHSSTSISAGLGMAVARDLSGEERNVVCVIGDGAMSAGMAYEAMNNAGAMDSRLIVILNDNDMSIAPPTGAMSAYLARLISGQTYRSLREIGKQIAGHLPKFVERGAARAEEFARGFWTGGTLFEELGFYYVGPIDGHNLDHLLPVLKNVRDAKTGPILVHVVTQKGKGYAPAEASADKYHGVVKFDVVTGAQVKAKSNAPSYTRVFAESLISQARHDPKVVAITAAMPSGTGLDLFGQVYPERTFDVGIAEQHAVTFAAGLAAEGFKPFCALYSTFLQRAYDQVVHDVALQGLPVRFIIDRAGLVGADGATHAGAFDIAFLACLPGMTVMAPADEAELVHMMATMVAFDDGPSAVRFPRGEGVGVERPERGEVLPIGKGRIVHGTGEGDIALLSLGTRLAACLDAAERLEAAGFTVTVADARFAKPLDRELVLKLAAGHGALVTVEEGSVGGFGSHVLQLVTDEGLLDRGAVKVRAMVLPDIYIDQETQARQLAAAGLDADAIVAKVEGLLGKAKAGVSLHKAG
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: RL15_BACLD
Sequence: MKLHELKPAEGSRKTRNRVGRGIGSGNGKTAGKGHKGQNARSGGGVRPGFEGGQMPLFQRLPKRGFTNINRKEFAVVNLDKLNSFAEGTEVTPELLLETGVISKLKSGVKILGDGKLEKKLTVKANKFSASAKQAIEAAGGTAEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: ATPF_STRP3
Sequence: MSITFGELVGNFILVTGSVIVLLLLIKKFAWGAIESILQTRSQQISRDIDQAEQSRLSAQQLEAKSQANLDASRSQASKIISDAKEIGQLQGDKLVAEATDEAKRLKEKALTDIEQSKSDAISAVKTEMSDLTVLLAKKIMGANLDKTAQSQLIDSYLDDLGEA
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: IMT1_MESCR
Sequence: MTTYTNGNYTQPKTLDKDEQLAGLAVTLANAAAFPMILKSAFELKILDIFSKAGEGVFVSTSEIASQIGAKNPNAPVLLDRMLRLLASHSVLTCKLQKGEGGSQRVYGPAPLCNYLASNDGQGSLGPLLVLHHDKVMMESWFHLNDYILEGGVPFKRAHGMIQFDYTGTDERFNHVFNQGMAHHTILVMKKLLDNYNGFNDVKVLVDVGGNIGVNVSMIVAKHTHIKGINYDLPHVIADAPSYPGVEHVGGNMFESIPQADAIFMKWVLHDWSDEHCVKILNKCYESLAKGGKIILVESLIPVIPEDNLESHMVFSLDCHTLVHNQGGKERSKEDFEALASKTGFSTVDVICCAYDTWVMELYKK
What is the function of this protein?
Catalyzes the methylation of myo-inositol into ononitol (1D-4-O-methyl myo-inositol), the first step in the biosynthesis of the cyclic sugar pinitol which has osmoprotective properties.
What are the official names of this protein?
Inositol 4-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.
Protein: HIS6_PSEF5
Sequence: MALAKRIIPCLDVDNGRVVKGVKFENIRDAGDPVEIARRYDEQGADEITFLDITASVDGRDTTLHTVERMASQVFIPLTVGGGVRTVQDIRNLLNAGADKVSINTAAVFNPEFVGEAAQHFGSQCIVVAIDAKKVSGPGEAPRWEIFTHGGRKPTGLDAVEWAKKMEGLGAGEILLTSMDQDGMKNGFDLGVTRAISDALGIPVIASGGVGNLQHLADGIIEGHASAVLAASIFHFGEYTVPEAKAYMAQRGIVVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYNS_NEUCR
Sequence: MPEQQRLASLDSSTASRLPAYSQTLFEAKTEKGLTFEAIAQHLGRSEVAVAGLFYGQVQASAEDVDKLSELLSVPKEAIAKQMMGFPDRGRAGPMPPVEPLIYRLYEIVQNYGYAFKAVMNEKFGDGIMSAICFNTTVDKEVDETGASWVVITLKGKWLPFARF
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: PSS3_ORYSJ
Sequence: MPVRRRWYPPSSTAAQPSPDGGDVNTDDADACPSSRQQRPPSLPQHSAPIHHRRRVINSIDASGEVMEYGSSNDQRMQDMEIWPSDGGGVEEYDPWTAWLYKPHTVSVLLAGACLLIWASGVLHPEITSSHDKVIPIKRGVWAMIAVFLAYCTLQAPSTILIRPHPAVWRLVHGMAVVYLVALTFLLFQKRDDARQFMKHLHPGLGVELPERSYGSDCRMYVPENPTNRFINIQETLFDEFVIAHVLGWWGKAVMIRNQLLLWVLSVGFELMELTFRHMLPNFNECWWDSIILDIMICNWFGIWAGMHTVRYFDGKTYEWVGLSRQPSIMGKVKRSLCQFTPAKWDKDQWHPFMEPRRFIQVFCLCVGFMTVELNTFFLKFCLWIPPRNPLVVYRLILWWLIAIPAIREYNTYLQDRSS
What is the function of this protein?
Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine.
What are the official names of this protein?
CDP-diacylglycerol--serine O-phosphatidyltransferase 3, Phosphatidylserine synthase 3.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL12_HCMVM
Sequence: MRVDRQKRNNFTYRQTVYIILTFYIVYRGKCNSTDTNNSTSTSDSTVSDTSVYSTPNLPSTFFTTLDTSTGSQISTTSNTISSTTNTLAASSITTLNTSTNTTSYTASTLTALSSTHTNSPILSNNATLYTTSLDNTTTDITSSESSINASTIHNTTYSPVTSIAVNCTVAANETNNSSSKNCQQDIGTIRVKSTTLTAEEGKNITIQGNSTWNCPNVVWYRHYNWSTHGHHIYPNRRYQTPTYQHKILTSHPICHPDVSSPAAYHDLCRSCNKTELRIYDLNTTNSGRYSRRCYKEYNHDGPHEDENFGLTVNPRNDTDNHTTPLCPRYVGTQSEEDEDDDYTLSTITNNNMRKTSHRDISHGTRTTWALTLICIACILLFFVRRALNKRYRPLRDDISESSFVVRYHPEHED
What are the official names of this protein?
Uncharacterized protein RL12.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein.
Protein: SYP_RICBR
Sequence: MLLSKYFLPVLKEDPSEAQITSHKLMLRSGMIRQQAAGIYSWLPLGLKVLKNIENIVRSNMDKAGCLEVLMPCIQPAHLWVESGRFDNYGKEMLKFQDRHDNTLLFGPTNEDMVTDIFRNNIKSYKDLPKNLYHIQWKFRDEIRPRFGVMRGREFLMKDAYSFDIDEESAVKTYNQMYKAYINTFRDLGVFAVPVIADNGPIGGKLSHEFHIIAETGESNIYYDKRFKTLKDNPDIDIEEIKSWYAAAEEKHDASKLSSDKEITSSKGIEVGHIFYIGTKYSVNMNALINDEHGKLTPIEMSSYGIGISRLVAAIIEANSDAKGIIWPIAVAPFKISLINLNIHDSKCLELAERVYNELLAQNIEVLYDDTDVRAGSKFATHDLIGSPYQIIIGPKKAANNIVELKNRKNGEIEDIDLNKRALNSYLTFFNS
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPH_STRGC
Sequence: MSATKMNAQEIIKFIADAKKKTPVKVTFNGELHGTIPWSVVKLGNVLFGDWEEIKPLLVNLEENKTYVVEQDARNSAVPLLDKRDINARIEPGAIIRDQVEIGDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAEPVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKTIDEKTQQKTALEDALRTL
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: MTNA_SCLS1
Sequence: MAGLEAIKYGRGRLEVLDQLRLPHEFVYDNVSTCEEAFDSIKSMRVRGAPAIAIVAALALAVELHHEKDGSKTKQEAVQYINKRLDYLLGSRPTAVDLSNAIKLLKRVSQSAAEATNALDDSAACADVRKGYIDAAEKILEDDLTTNLAIGRYGAEYLRRQQMPIGGEEDDEDPSKFFTTSPPCTQGAPDRTYRKLSVLTHCNTGSLATSGHGTALGIIRSLHKMNYLDHAYCTETRPYNQGSRLTAFELVYEKIPSTLITDSMAGALFARMKESKNISAVIVGADRVARNGDTANKIGTYSLAVLAKAHNIKFIVAAPTTSIDLETVSGADIKIEDRAPTELTQISGAVVGKDGHVDVNTTARVAIAHQGIDVWNPSFDVTPSMYIDAVITEKGEVVRSSKGTFDFKTIMPERWAQQVEGKELSAETNVKAHVDDGTQFPMENI
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS21_RICRS
Sequence: MILVNVHAGNCDNTLKNFKKKLQRELYFRKMKEQRYYETPSAKRVRKAQEAARRQRKFARKKMFDE
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: MSH2_ARATH
Sequence: MEGNFEEQNKLPELKLDAKQAQGFLSFYKTLPNDTRAVRFFDRKDYYTAHGENSVFIAKTYYHTTTALRQLGSGSNALSSVSISRNMFETIARDLLLERNDHTVELYEGSGSNWRLVKTGSPGNIGSFEDVLFANNEMQDTPVVVSIFPSFHDGRCVIGMAYVDLTRRVLGLAEFLDDSRFTNLESSLIALGAKECIFPAESGKSNECKSLYDSLERCAVMITERKKHEFKGRDLDSDLKRLVKGNIEPVRDLVSGFDLATPALGALLSFSELLSNEDNYGNFTIRRYDIGGFMRLDSAAMRALNVMESKTDANKNFSLFGLMNRTCTAGMGKRLLHMWLKQPLVDLNEIKTRLDIVQCFVEEAGLRQDLRQHLKRISDVERLLRSLERRRGGLQHIIKLYQSTIRLPFIKTAMQQYTGEFASLISERYLKKLEALSDQDHLGKFIDLVECSVDLDQLENGEYMISSSYDTKLASLKDQKELLEQQIHELHKKTAIELDLQVDKALKLDKAAQFGHVFRITKKEEPKIRKKLTTQFIVLETRKDGVKFTNTKLKKLGDQYQSVVDDYRSCQKELVDRVVETVTSFSEVFEDLAGLLSEMDVLLSFADLAASCPTPYCRPEITSSDAGDIVLEGSRHPCVEAQDWVNFIPNDCRLMRGKSWFQIVTGPNMGGKSTFIRQVGVIVLMAQVGSFVPCDKASISIRDCIFARVGAGDCQLRGVSTFMQEMLETASILKGASDKSLIIIDELGRGTSTYDGFGLAWAICEHLVQVKRAPTLFATHFHELTALAQANSEVSGNTVGVANFHVSAHIDTESRKLTMLYKVEPGACDQSFGIHVAEFANFPESVVALAREKAAELEDFSPSSMIINNEESGKRKSREDDPDEVSRGAERAHKFLKEFAAIPLDKMELKDSLQRVREMKDELEKDAADCHWLRQFL
What is the function of this protein?
Component of the post-replicative DNA mismatch repair system (MMR).  Forms three different heterodimers: MutS alpha (MSH2-MSH6 heterodimer), MutS beta (MSH2-MSH3 heterodimer) and MutS gamma (MSH2-MSH7 heterodimer) which binds to DNA mismatches thereby initiating DNA repair.  MutS alpha and MutS beta recognize single base mismatches and trinucleotide insertion-deletion loops (IDL) in the DNA.  MutS gamma recognizes specifically the T/G single base mismatch.  Plays a role in DNA homologous recombination repair and has a broad range of anti-recombination effects.  Can suppress recombination between divergent direct repeats in somatic cells and possesses an anti-recombination meiotic effect.  Is involved in a UV-B-induced DNA damage response pathway.
What are the official names of this protein?
DNA mismatch repair protein MSH2, AtMSH2, MutS protein homolog 2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: REP_TYLCI
Sequence: MPRLFKIYAKNYFLTYPNCSLSKEEALSQLKKLETPTNKKYIKVCKELHENGEPHLHVLIQFEGKYQCKNQRFFDLVSPNRSAHFHPNIQAAKSSTDVKTYVEKDGNFIDFGVSQIDGRSARGGQQSANDAYAEALNSGSKSEALNILKEKAPKDYILQFHNLSSNLDRIFSPPLEVYVSPFLSSSFNQVPDELEEWVAENVVYSAARPWRPISIVIEGDSRTGKTMWARSLGPHNYLCGHLDLSPKVYSNDAWYNVIDDVDPHYLKHFKEFMGAQRDWQSNTKYGKPIQIKGGIPTIFLCNPGPTSSYREYLDEEKNISLKNWALKNATFVTLYEPLFASINQGPTQDSQEETNKA
What is the function of this protein?
Essential for the replication of viral ssDNA.  The closed circular ssDNA genome is first converted to a superhelical dsDNA.  Rep binds a specific region at the genome origin of replication.  It introduces an endonucleolytic nick within the conserved sequence 5'-TAATATTAC-3' in the intergenic region of the genome present in all geminiviruses, thereby initiating the rolling circle replication (RCR).  Following cleavage, binds covalently to the 5'-phosphate of DNA as a tyrosyl ester.  The cleavage gives rise to a free 3'-OH that serves as a primer for the cellular DNA polymerase.  The polymerase synthesizes the (+) strand DNA by rolling circle mechanism.  After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication.  Displays origin-specific DNA cleavage, nucleotidyl transferase, ATPase and helicase activities.
What are the official names of this protein?
Replication-associated protein, Rep, Protein C1.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae Rep protein family.
What are the subcellular locations of this protein?
Host nucleus.