PharMolix/UniProtQA huggingface dataset:
Protein: NU4M_POLOR
Sequence: MLKLLIPTIMLFPMIWTLNPKWLWSATTTHSLIIASLSLTLFKCYSTTQWSNLNYMLATDMISTPLIILTCWLLPLMIIASQNHMSTEPINRQRSYITLLVSLQALLIMAFSATEIILFYIMFESTLIPTLIIITRWGNQTERLNAGIYFLFYTLAGSLPLLVALLYLYNTAGSLSFISMNLISIPPNTWTNTFLWVACVTAFLVKMPLYGVHLWLPKAHVEAPVAGSMILAAILLKLGGYGMIRMTIMLEPATKSLAYPFIILALWGIIMTGSICMRQSDMKSLIAYSSVSHMGLVASGILIQTTWGFTGAIILMIAHGLTSSALFCLANTAYERTHSRTLLLARGMQIILPLMATWWFIMSLANMALPPLPNLMGELMILVSMFNWSNWTILLTGTGTLITASYSLYLYMSSQRGPTPNNLTFMELSHTREHLLLTLHIIPIILLMIKPELIWGWCW
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: PRIS_SULIY
Sequence: MGTFTLHQGQSNLIKSFFRNYYLNAELGLPNDMELREFALQPFGSDMYIRHLSFSSSEELRDYLVNRNLPLHLFYSSARYQLPSARDMEEKAWMGSDLLFDIDADHICKLRSIRFCPVCGNAITSEKCERDNVETLEYVEMTSECIKRGLEEARNLVEILEDDFGLKPKVYFSGNRGFHVQVDCYGDCALLDSDERKEIAEYVMGVGVPSYPGGSESAPGWVGRKNRGINGVTIDGQVTIDVKRLIRIPNSLHGKSGLIVKEVTNLDDFEFNEALSPFTGYTIFLPYISIETEVLSRNIKLNRGVPIKIESSIGIYLHLKNLGEVKAYVR
What is the function of this protein?
Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  The small subunit contains the primase catalytic core and has DNA synthesis activity on its own.  Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability.  The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis.  May also play a role in DNA repair.
What are the official names of this protein?
DNA primase small subunit PriS.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase small subunit family.
Protein: NORR_AERHH
Sequence: MISTDSLARIALDLQLGISHQDRFHRLIQSVRSLLNSDASALLRYEGGQFIPLAIDGLMQDVLGRRFALKDHPRMEAIARAGDVVRFPADSSLPDPYDGLLPDHDDFKVHACVGLPLFSDQALIGALTIDGMNPTQFDAISDEELRLVGALAAAALNNALLLERLARQSSEPLVPGTRPGPEQPEMIGQSPAMARLRHEIEVVANSELNVLILGETGVGKELIAKAVHRGSQRAKAPLVYLNCAALPESVAESELFGHVKGAFTGAIHNRAGKFELADQGTLFLDEIGELSLPLQAKLLRVLQYGDLQRIGDDTPLKVNVRILAATNRDLKQAVVEGQFRADLYHRLSVFPIHAPALRERPGDIPLLAGYFCERCRLSLGLEQLRIQPQALQLLERHDWPGNVRELEHAIHRAAVLARAEQGSQTPTLASHHFNLAAGPLPPSTSPAMAPMTPLPGGLGLRAATDAFQLALIEQTLAAHNGNWAATARALELDSGNLHRLAKRLGLKA
What is the function of this protein?
Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon.  Activation also requires sigma-54.
What are the official names of this protein?
Anaerobic nitric oxide reductase transcription regulator NorR.
Protein: RL23_BIFLS
Sequence: MVAIHKPAHDVILKPVVSEKSYAASDRGQYTFVVAPDANKVQIKQAIEEIFKVKVTNVNTLNRAGKKQRTRTGFGQRASQKRAIVTVAEGQTIDIFGN
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: NCAP_BRSV3
Sequence: MALSKVKLNDTFNKDQLLSTSKYTIQRSTGDNIDIPNYDVQKHLNKLCGMLLITEDANHKFTGLIGMLYAMSRLGREDTLKILKDAGYQVRANGVDVITHRQDVNGKEMKFEVLTLVSLTSEVQGNIEIESRKSYKKMLKEMGEVAPEYRHDFPDCGMIVLCVAALVITKLAAGDRSGLTAVIRRANNVLRNEMKRYKGLIPKDIANSFYEVFEKYPHYIDVFVHFGIAQSSTRGGSRVEGIFAGLFMNAYGAGQVMLRWGVLAKSVKNIMLGHASVQAEMEQVVEVYEYAQKLGGEAGFYHILNNPKASLLSLTQFPNFSSVVLGNAAGLGIMGEYRGTPRNQDLYDAAKAYAEQLKENGVINYSVLDLTTEELEAIKNQLNPKDNDVEL
What is the function of this protein?
Encapsidates the viral RNA genome by forming a left-handed helical nucleocapsid that protects the RNA from nucleases.  RNA replication depends on the availability of soluble nucleoprotein.  The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.  Together with the phosphoprotein, sequesters host NF-kappa-B in inclusion bodies (IBs) thereby inhibiting this host defense pathway.  May also act as a modulator of the innate immune response by sequestration of host IFIH1/MDA5 and MAVS into IBs.
What are the official names of this protein?
Nucleoprotein, Protein N, Nucleocapsid protein.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses nucleocapsid family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Localizes in cytoplasmic inclusion bodies.
Protein: HYEP_MANSE
Sequence: MYKILSSFVAGVAIGSGLVITYVLYNVPEPPELDLQRWWGIGTRPTEEDKSIRPFSIDFNDTVILDLKERLKNRRPFTKPLEGINSEYGMNTEYLETVLEYWLNEYNFKKRAELLNKFPHYKTRIQGLDLHFIRVKPEIKEGVQVLPLLMMHGWPSSSKEFDKVIPILTTPKHEYNIVFEVVAVDLPGYGFSEGTNKPGLNPVQIGVMMRNLMLRLGFEKFYIQAGDWGSQCATHMATLFPDQVLGLHTNMPLSSRPLSTVKLFIGALFPSLIVDAKYMDRIYPLKNLFSYILRETGYFHIQATKPDTIGVALTDSPAGLAGYLIEKMAICSNRDQLDTPHGGLENLNLDDVLDTVTINWINNCIVTSTRLYAEGFSWPEVLIVHRIPSMVPTAGINFKYEVLYQPDWILRDKFPNLVRSTVLDFGGHFAALHTPQALADDIFASAVQFLKFHDRKRNQKSS
What is the function of this protein?
Catalyzes juvenile hormone hydrolysis.
What are the official names of this protein?
Juvenile hormone epoxide hydrolase, JHEH, Juvenile hormone-specific epoxide hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S33 family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: CH60_BACC0
Sequence: MAKDIKFSEEARRSMLRGVDTLANAVKVTLGPKGRNVVLEKKFGSPLITNDGVTIAKEIELEDAFENMGAKLVAEVASKTNDVAGDGTTTATVLAQAMIREGLKNVTAGANPMGLRKGIEKAVVAAVEELKTISKPIEGKSSIAQVAAISAADEEVGQLIAEAMERVGNDGVITLEESKGFTTELDVVEGMQFDRGYASPYMITDSDKMEAVLDNPYILITDKKISNIQEILPVLEQVVQQGKPLLIIAEDVEGEALATLVVNKLRGTFNVVAVKAPGFGDRRKAMLEDIAILTGGEVITEELGRDLKSATVESLGRAGKVVVTKENTTVVEGVGSTEQIEARIGQIRAQLEETTSEFDREKLQERLAKLAGGVAVIKVGAATETELKERKLRIEDALNSTRAAVEEGIVAGGGTSLMNVYTKVASIVAEGDEATGINIVLRALEEPVRQIAINAGLEGSVVVERLKGEKVGVGFNAATGEWVNMLETGIVDPAKVTRSALQNAASVAAMFLTTEAVVADKPEPNAPAMPDMGGMGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPE_BACCA
Sequence: MSADGLAAFLAEANEFRTIPIVRKFVADVIEPLGVFANLREEAVFLLESKDDESPWARYSFIGVAPFLTLESETGETFSVKDENGNEQITAPTLKEAFQWVERTLAVKPLAETVPFTGGAVGFLGYDFISAIEKVPRHKNRDVPMKTAYFVFCESLFAFDQKKRELLVIHYIRLSGNETEEEKIEAYRAAERRMADLAAKAARPQAEQPLLPAESESGRTASFAKAVSNYDKKQFLRDVEAVKRYIAAGDVFQAVLSQRFCVPVQAGGFAIYRLLRYINPSPYMFYFQLDGVEIVGSSPEKLIQVHRRRVEIDPIAGTRRRGRSPEEDERLADELYHDPKERAEHYMLVDLARNDIGRVAKYGTVEVPVLLQIGKFSHVMHLISKVVGELDDNVHPIDALLAAFPAGTVSGAPKVRAMQILQELEPTARGLYAGAIAYIGFDGNIDSCIAIRTAVVKDGYAYVQAGAGIVADSVPELEWKETRNKASALMNAIEQAERLFAKGERAVC
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 1, AS, ASI.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.
Protein: ORN_METCA
Sequence: MAQDAQNLIWIDLEMTGLDPQNDAIIEIATIVTDGQLNVLAEGPVLAIHQPESVLDRMDDWNRKQHGESGLTERVRRSTIGEAEAEHLTLGFVSEWVPPNESPICGNSICQDRRFLARCMPRLEAYFHYRNLDVSTLKILVERWAPALKEGLQKQSTHRALDDIRESIAELRYYRDTVLKI
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_SALPK
Sequence: MLKQVEIFTDGSCLGNPGPGGYGAILRYRGHEKTFSEGYTLTTNNRMELMAAIVALEALKEHCEVTLSTDSQYVRQGITQWIHNWKKRGWKTAEKKPVKNVDLWKRLDAALGQHQIKWVWVKGHAGHPENERCDELARAAAMNPTQEDSGYQAEA
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTC1_ZYGRC
Sequence: MNNRPIPRNQASSSLGRNDLKPGLFGRSSFRVQHYSGTNGISPIGSSPRTKISPRYSFASSFATSESSLRESSYFDERPPVQDTGVPKSSGLYYSRASPKELSSIDRINDSSFNGIVCAGKTHLGLYKFSPQDKSIDCMHDFVSAGNDGNRGSNVQMGLGKRSKRTKLSTIADVKAGFHNHKNYVAICSNSTVLSIYDINKTGSIDNPLVTNCSQHVRSVNSFDFNMVQTNLIISGGQDSCIKIWDLRSSRSRTLSRADVNINTASDSIRDVKWMPHPTACRSASQNDLRSGVGGAAGYKFASIHDSGLLLKFDLRQPNQVEKRINAHSGPGLCLNWHPYQDYISTGGRDGKCCLWYVGDGKPGTDFLQAGNTSVNTPHSMTSNLPTNLSVVPDMTINCGFPVTKLKVRPCYEKNVLNSLVSMSSMAEDFGVSIYSLARKYIPKYNLSTSSASLGFVWWDDNLIFNIDKDNRINGWYLDREPTVLDNMPKIVTRWRDIEGNGLLFIDQDRGGYQVNDEVPANIEESKKPPNQRVSINSLSGTAGGGNSGGGSNSGMIGSIKKGISQTGLTSFAGERPALSKTGLNFSNKSLATQSMNNSHSNSFSSYAGAGPGPLNEVADYSGIESPFLMTIDLPYILNNMRVSQLPPERKSLYSPEVQAIRESPVKVFKFLAKELEFSYMQEGRSGEMKNATQLSNVNEDTTKKDLMVKFGISEKSTWTALVNKKNEAVEAISKKSVSTKEGSESLIESDGESSAKSHESDDNSSDADKKENAKDGTMHVQEKIDILLELIPICGHNASVYSYIDDLPNFKIWILIRDSLLWDLERLSVEYPDEKLPETQSTDQIGQPITMGNDDSLASDTRSYMTSDLNYFVEEHPRALRSDSDEPKDHKKPLSGLKSQLTKIQETEASIDDSLNPPKMLKKPDNPIKQEQIGSRLNDDSDSAVLEDDDNEEKSDFDTQIKGIPITNKRQPRQSFIDTYMGGLKSPIGSSNANNEFFMGRVGHSLGHSSPGSKGSPMASLNNGEFTYPGFKRMSSRNDRRSSGSLFLSPLKRRESSTAEFFNKSPMRPLSPVAPVSSFKSNPTEFLPPWNTRRLLKQIFKQAVEMGNILLVVNILFLFQNLYQLTSTEVLKNTLAQFIKILHKHELFELSAAILKCSPWEVVINADGGQSLVPIFCDKCGKLITNEPSKEKFTLEAQEKGNSMPLQRFGYWYCDSCKKPNTLCVFCERPIKTLAIGLLECGHEGHFQCLQSWFLDEGMAECPGGCMNQIRL
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RTC1 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: CNOT7_DANRE
Sequence: MPAATVDHSQRICEVWACNLEEEMKRIRQVTRKFNYIAMDTEFPGVVARPIGEFRSNADYQYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTSSGIQFKKHEEEGIETMYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILSNSKLPDEEVDFFEILRLFFPIIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFKMREMFFEDHIDDAKYCGHLYGLGSGSSYVQNGTGNAYEEEANKQQS
What is the function of this protein?
Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate.  Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.  During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation.  Additional complex functions may be a consequence of its influence on mRNA expression (By similarity).
What are the official names of this protein?
CCR4-NOT transcription complex subunit 7, CCR4-associated factor 1, CAF-1.
What is the protein family that this protein belongs to?
Belongs to the CAF1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: PLK2_HUMAN
Sequence: MELLRTITYQPAASTKMCEQALGKGCGADSKKKRPPQPPEESQPPQSQAQVPPAAPHHHHHHSHSGPEISRIIVDPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTVPDFHLSSPAKNFFKKAAAALFGGKKDKARYIDTHNRVSKEDEDIYKLRHDLKKTSITQQPSKHRTDEELQPPTTTVARSGTPAVENKQQIGDAIRMIVRGTLGSCSSSSECLEDSTMGSVADTVARVLRGCLENMPEADCIPKEQLSTSFQWVTKWVDYSNKYGFGYQLSDHTVGVLFNNGAHMSLLPDKKTVHYYAELGQCSVFPATDAPEQFISQVTVLKYFSHYMEENLMDGGDLPSVTDIRRPRLYLLQWLKSDKALMMLFNDGTFQVNFYHDHTKIIICSQNEEYLLTYINEDRISTTFRLTTLLMSGCSSELKNRMEYALNMLLQRCN
What is the function of this protein?
Tumor suppressor serine/threonine-protein kinase involved in synaptic plasticity, centriole duplication and G1/S phase transition.  Polo-like kinases act by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains.  Phosphorylates CENPJ, NPM1, RAPGEF2, RASGRF1, SNCA, SIPA1L1 and SYNGAP1.  Plays a key role in synaptic plasticity and memory by regulating the Ras and Rap protein signaling: required for overactivity-dependent spine remodeling by phosphorylating the Ras activator RASGRF1 and the Rap inhibitor SIPA1L1 leading to their degradation by the proteasome.  Conversely, phosphorylates the Rap activator RAPGEF2 and the Ras inhibitor SYNGAP1, promoting their activity.  Also regulates synaptic plasticity independently of kinase activity, via its interaction with NSF that disrupts the interaction between NSF and the GRIA2 subunit of AMPARs, leading to a rapid rundown of AMPAR-mediated current that occludes long term depression.  Required for procentriole formation and centriole duplication by phosphorylating CENPJ and NPM1, respectively.  Its induction by p53/TP53 suggests that it may participate in the mitotic checkpoint following stress.
What are the official names of this protein?
Serine/threonine-protein kinase PLK2, Polo-like kinase 2, PLK-2, hPlk2, Serine/threonine-protein kinase SNK, hSNK, Serum-inducible kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cell projection, dendrite. Note=Localizes to centrosomes during early G1 phase where it only associates to the mother centriole and then distributes equally to both mother and daughter centrioles at the onset of S phase.
Protein: GPDA_NEIM0
Sequence: MKITVIGAGSWGTALALHFSQHGNRVSLWTRNADQVRQMQEARENKRGLPGFSFPETLEVCADLADALKDSGLVLIVTSVAGLRSSAELLKQYGAGHLPVLAACKGFEQDTGLLTFQVLKEVLPDNKKIGVLSGPSFAQELAKQLPCAVVLASENQEWIEELVPQLNTTVMRLYGSTDVIGVAVGGAVKNVMAIATGLSDGLEYGLNARAALVTRGLAEITRLASAMGAQPKTMMGLAGIGDLILTCTGALSRNRRVGLGLAEGKELHQVLVEIGHVSEGVSTIEEVFNTACKYQIDMPITQTLLQLIRKEMTPQQVVERLMERSARFE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SARV_STAA8
Sequence: MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
What is the function of this protein?
Part of the pathway by which MgrA and SarA control autolysis.  Involved in regulation of virulence and autolysis genes such as hla, splA, aur, scp, lrgB, scdA and atl.  May also act as an activator for the expression of regulatory genes agr, lytSR and ArlRS.
What are the official names of this protein?
HTH-type transcriptional regulator SarV, Staphylococcal accessory regulator V.
What is the protein family that this protein belongs to?
Belongs to the SarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_EHRRW
Sequence: MSIDNELSKCRNIGIMAHIDAGKTTTTERILFYTGKQNRIGEVHEGAASMDWMEQEKERGITITSAATTCFWNDHRINIIDTPGHVDFTIEVERSLRVLDGAVAVFDGVAGVEPQSETVWRQADKYNVPRICFMNKMDRMGANFYRCVDMVIDRLGATPLVLQLPIGIEKDFVGVVDLLEMRSIIWDEESLGASFHYGEIPGDMIDIAHEYRHKLLESAVELNDDAMNLYFEGKEVPVSLLKNCIRLGVIQSKFVPVLCGSAFKNRGVQPLLDAVVDFLPAPNDVAMIEGIDVKTSNPVSIKSSVNEKFVALAFKVMTDKFVGSLTFIRIYSGKLSSKTTVLNAVKNSTESIGRILLMHANNREDITEAKAGDIVALAGLKKTVTGDTLCALDYPVVLERMEFPDPVMEIAVEPKSTADQEKMGIALSRLVSEDPSLGMCVNPESGQTILKGMGELHLEVIVDRMRREFNVEANIGAPQVAYRETITKSVEIEYIHKKQTGGAGQFAKVNILFEPLPPGSGFQFESKITGGAIPKEYIPGVQNGLEAIRGSGMLAGFPVIDFKATLFDGAFHEVDSSPLAFELAAKGAFRDMVNKAGAILLEPIMKVEIVTPDEYMGDVIGDVNSRRGRVAEMQDRNNTKVILAFIPLAKMFGYVKDLRSMSQGRAQYSMYFSCYEQVPDNILASEIKK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYK_MYCGA
Sequence: MSKKLNDQELVRLDKLNRLIESKQNPYEVTKVANTHNTKSLKEKYDQFSKEQLAEMQLDKPITVSGRVILIRRTFILIQDFHSELQLYINKNKQPDLFKYFNDYLDLGDVVCATGKPMKTNTNELSLDLESLKIISKSLRVPPEKFHGIADEEIRSRKRYLDLVYNKESKERFVYRSKIIAAMRQYFNENGFLEVETPFLHAQIGGAAAKPFVTRYNALDRDYYLRIAPELPLKKLIVGSFEKIYEIGKCFRNEGMDSTHNPEFTSVETYVAYVDYIYMMELTEAIIKYIAKAIGISHTNIKNETIDWNKPFKRIKMTELVKQETGIDFTQVKKIDQALDLAKKHKVHVKEHEKTIGHIINLFFEEFCEKKLVEPTFVTHHPVEISPLSKLDYSDPRYTERFELFAFGKELANGFSELNDPIDQRQRFEKQLEEKQKGNDEASEMDEDFLEALENGLPPTGGLGIGVDRLVMMLTGTTSIRDILFFPHVREE
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1426_RALSO
Sequence: MANPERIDVMVCLATVTPPKLVQVQVSATATVADAVRASGLLEEVGLSIDACRLGVYGKRKAPDALLHAHDRVEITGPLIADPKAARRRRVRRVRATGTREGLKWLRNEAPPEDDVAG
What are the official names of this protein?
UPF0125 protein RSc1426.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: Y945_METJA
Sequence: MLLRQYINVPRLGEIMNLKELTVILIIPIVYLGVCGCFEIVPKSFYDNFSSYNVGDKAPFGEWKVKEGGFKIEAILSEDKKTLNKVAVPINNGIIYIDKNYTDFKFIVDIKRLEESDSPKIYFRLINNANAGYYIDIEGFDRGYVLYKFNGTKVEKLAESYDAAPAGTDFYRYEVVAKDNKIIFLAGGQKYIEYTDNNTPILKGGIGIGGGRAYYDNVRVEPIE
What are the official names of this protein?
Uncharacterized protein MJ0945.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PDCL3_PONAB
Sequence: MQDPNADTEWNDILRKKGILPPKESLKELEEEAEEEQRILQQSVVKTYEDMTLEELDDHEDEFNEEDERAIEMYRRQRLAEWKVTKLKNKFGEVLEISGKDYVQEVTKAGEGLWVILHLYKQGIPLCALINQHLSGLARKFPDVKFIKAISTTCIPNYPDRNLPTIFVYLEGDIKAQFIGPLVFGGMNLTRDELEWKLSESGAIMTDLEENPKKPIEDVLLSSVRRSALMKRDSDSEGD
What is the function of this protein?
Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, increasing its abundance by inhibiting its ubiquitination and degradation (By similarity).  Inhibits the folding activity of the chaperonin-containing T-complex (CCT) which leads to inhibition of cytoskeletal actin folding (By similarity).  Acts as a chaperone during heat shock alongside HSP90 and HSP40/70 chaperone complexes (By similarity).  Modulates the activation of caspases during apoptosis (By similarity).
What are the official names of this protein?
Phosducin-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the phosducin family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Endoplasmic reticulum.
Protein: LDH_STAEQ
Sequence: MKKFGKKVVLVGDGSVGSSYAFAMVTQGIADEFVIIDIAKDKVEADVKDLNHGALYSSSPVTVKAGEYEDCKDADLVVITAGAPQKPGETRLQLVEKNTKIMKSIVTSVMDSGFDGFFLIAANPVDILTRYVKEVTGLPAERVIGSGTVLDSARFRYLISKELGVTSSSVHASIIGEHGDSELAVWSQANVGGISVYDTLKEETGSDAKANEIYINTRDAAYDIIQAKGSTYYGIALALLRISKALLNNENSILTVSSQLNGQYGFNDVYLGLPTLINQNGAVKIYETPLNDNELQLLEKSVKTLEDTYDSIKHLV
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_PROMH
Sequence: MHSTDTIVAQATPPGRGGVGILRVSGPKAAVVAQTILGKVPKPRYADYLPFRNEDNSVLDQGIALFFPNPNSFTGEDVLELQGHGGPIILDLLLKRILQIPGIRIAKPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSAINSLQGAFSSHINEMVESLTNLRIYVEAAIDFPDEEIDFLSDGVIEGKLNTVISQLDDVRTQARQGSLLREGMKVVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLREASDEVERIGIERAWQEIEQADRVLFMVDSTTTEATTPEEIWPEFMARLPSTLPVTVIRNKSDLTGEPAEITSQGDYPMIRLSARDGMGIELLRSHLKEAMGFNSNTEGGFLARRRHLQALNTAAEHLQQGYQQLVYAKSGELLAEELRLAQQALSEITGEFTSDDLLGRIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALLB_SALPK
Sequence: MSFDLIIKNGTVILENEARVIDIAVQGGKIAAIGENLGEAKNVLDATGLIVSPGMVDAHTHISEPGRTHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRETIELKFDAAKGKLTIDAAQLGGLVSYNLDRLHELDEVGVVGFKCFVATCGDRGIDNDFRDVNDWQFYKGAQKLGEMDQTVLVHCENALICDELGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKAAGCRLHVCHISSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDQENQKGMWEKLFNGEIDCLVSDHSPCPPEMKAGNIMQAWGGIAGLQNCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLKHKGRIAPGKDADLVFIQPDSSYVLKNEDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEHGFPVPPKGQFILKHQQ
What is the function of this protein?
Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.
What are the official names of this protein?
Allantoinase, Allantoin-utilizing enzyme.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.