PharMolix/UniProtQA huggingface dataset:
Protein: CMR1_EMENI
Sequence: MVKEELSEFEKQRLANIAERDALLKKLSLDAQSTGVFTSNMPRGTSANQSKPKKKPAPKVKKEESLLPRRTSSRLRGIAADSEIAKRKADEEYDRRQEEERAKRVRKSDSFSFNDIFVSGQKLSGDALIGVDVVTKGVAVPYQRTFGEEDIKSTDDKDLKALRKEMNSLSLWEAWEPNRIKITPERIYSMTFHPSEAKPVIFAGDKMGHLGILDASQEKPTSAVKNEDDEDDEDDDDPDPVLVTLKPHTRTISSMTVHPSKPTHLYTASYDSSIRELDLEKTSSVEKYAPESTSDDVPISGLDMAAGDPNTIYWTTLDGAFGRYDMRTKRQSSATTWQLSEKKIGGFSLYQTHPHYVATASLDRTMRLWDIRNLSHTDPTPVGEHQSRLSVSHAAFNCVGQIATSSYDDTLKLYDFSSKGISSWKPGHILDESEMKPDTIVRHNCQTGRWVTILRPQWQLNPQSAIQRFCIGNMNRFVDIYSGSGDQLAQLGGDGITAVPAVAVFHRSKNWVAGGTASGKICLWM
What is the function of this protein?
DNA-binding protein that binds to both single- and double-stranded DNA.  Binds preferentially to UV-damaged DNA.  May be involved in DNA-metabolic processes.
What are the official names of this protein?
DNA damage-binding protein cmr1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DDB2/WDR76 family.
Protein: DAPB_OLEA2
Sequence: MSVSVIVMGAGGRMGTTITGMVRADGECRLAGVVEREGRREGLEHLGCQVAGTLEELLPGMPDAVVIDFTAPEASVHNARACARHGSGLVIGTTGFTEEQKAELADCALQTPVFWAPNMSVGVNVLLKILPQLVTLLGEQYDLEMVELHHNKKKDSPSGTALRLAECLAEARKWDLDTVANYHREGIIGERPHEEIGIQTIRGGDVVGVHTVYALGPGERIEVTHQAHSRETFAAGAIRAAKWLAQNRPGKLYTMSDML
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZAPA_ECO55
Sequence: MSAQPVDIQIFGRSLRVNCPPDQRDALNQAADDLNQRLQDLKERTRVTNTEQLVFIAALNISYELAQEKAKTRDYAASMEQRIRMLQQTIEQALLEQGRITEKTNQNFE
What is the function of this protein?
Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring.  It is recruited early at mid-cell but it is not essential for cell division.
What are the official names of this protein?
Cell division protein ZapA, Z ring-associated protein ZapA.
What is the protein family that this protein belongs to?
Belongs to the ZapA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at mid-cell.
Protein: RNPH_FRASN
Sequence: MIRVDGRTTDQLRDVTIERGWQEHAEGSALISAGRTRVLCAASVTEGVPRWRKGSGLGWVTAEYSMLPRATHTRNDRESVRGRIGGRTHEISRLIGRSLRAAIDLKALGENTIAIDCDVLLADGGTRTAAITGAYVALADACRWLGRPAAIVTSVCAVSVGVVGGVPMLDLAYTEDSTADTDMNVVRTGAGGFVEVQGTAEGTPFERSTLDELLDLAVAGCTRLTEIQNAALAAPPAAGPPAPERAGAGSGSGGKGTGSR
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: TRPE_PSEAE
Sequence: MNREEFLRLAADGYNRIPLSFETLADFDTPLSIYLKLADAPNSYLLESVQGGEKWGRYSIIGLPCRTVLRVYDHQVRISIDGVETERFDCADPLAFVEEFKARYQVPTVPGLPRFDGGLVGYFGYDCVRYVEKRLATCPNPDPLGNPDILLMVSDAVVVFDNLAGKIHAIVLADPSEENAYERGQARLEELLERLRQPITPRRGLDLEAAQGREPAFRASFTREDYENAVGRIKDYILAGDCMQVVPSQRMSIEFKAAPIDLYRALRCFNPTPYMYFFNFGDFHVVGSSPEVLVRVEDGLVTVRPIAGTRPRGINEEADLALEQDLLSDAKEIAEHLMLIDLGRNDVGRVSDIGAVKVTEKMVIERYSNVMHIVSNVTGQLREGLSAMDALRAILPAGTLSGAPKIRAMEIIDELEPVKRGVYGGAVGYLAWNGNMDTAIAIRTAVIKNGELHVQAGGGIVADSVPALEWEETINKRRAMFRAVALAEQSVE
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan (PubMed:2105306, PubMed:23449919).  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 1, AS, ASI.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.
Protein: PYRDA_LIMRD
Sequence: MQETQRLAVELPGLSLKNPIIAASGTCGYGQEAAKKYNLNHLGSLVLKSTTLYPRQGNPRPRVCETSAGWLNANGLQNVGITAATNEKIPWLRKNYPQLPIIASAAGFSEDEYVKVVSEFANTAGVKAIELNVSCPNVKHGGMAMGTDPEVLQRLVKQVVKAALGIPIYVKLTPNVTNIVPLAQAAEQGGANGLTMINTLTGLSIDLKTRRPALANVTGGLSGPAIKPLALRMIHQVRQVSSLPIIGVGGIESAEDVLEFMMAGANAVQIGAASFHDPLACPKIAADLPIVMDRYGIKKLTDLWEVRF
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase A (fumarate), DHOD A, DHODase A, DHOdehase A.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GHRB_ECOHS
Sequence: MKPSVILYKALPDDLLQRLQEHFTVHQVANLSPQTVEQNAAIFAEAEGLLGSNENVDAALLEKMPKLRATSTISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTARRVVEVAERVKAGGWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLIDALQGKVEKNCVNPHVAD
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase B.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_DESVH
Sequence: MRIALTNDDGIQAPGLRAIYKALIEAGHTVDVVAPVTEQSAVGHAVTIAMPLRVKVFHENGFRGHGVYGTPTDCMKLGLSSLLEHKPELVVSGINAGANVGPDILYSGTVSAATEAAHMGYRAVALSYDSFRPEDISAHARHAAALLPHIEWAGLPERCVVNINYPAVPVESIKGVRVCPQTRAVWHDWYEHRTDPRGGSYWWLNGVIPPETVAPGTDRALLTEGYITVTPLRFDFTDSETLTRLASLEE
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AZOR2_CLOAB
Sequence: MSKVLYIKANAKPEGVSRTFKISDSFIEEYRNQKPNDEIITLDLYKEGISFLTEEAIKLHVPKQGEGKDHHVLKYAYQFAEADKYVIAAPFWNLSFPAILKAYIDYICVTGITFKYTEEGAVGLCQGKKAVHIVSRGGGYSEGPFEMYEMGDRYLRTIFGFLGITDFTTIVAEKLDVVGEDVEGILRNTIEKAKEQAKEF
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase 2, Azo-dye reductase 2, FMN-dependent NADH-azo compound oxidoreductase 2, FMN-dependent NADH-azoreductase 2.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: RL9_CAEEL
Sequence: MKLIESNDTVVFPEGVTFTVKNRIVHVTGPRGTIRKDFRHLHMEMERIGKSTLRVRKWFGVRKELAAIRTVCSHIKNMIKGVTVGFRYKMRSVYAHFPINVTLQDGNRTVEIRNFLGEKIVRRVPLPEGVIATISTAQKDEIVVEGNDVQFVSQAAARIQQSTAVKEKDIRKFLDGIYVSEKTTIVPTD
What are the official names of this protein?
60S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: ADPRH_STRP3
Sequence: MPSSFDLLGEMIGLLQTEQLTSSWACPLPNALTKRQDLWRALINQRPALPLSKDYLNLEDAYLDDWRASFVPVSVKDCQKTNYTSLFLYHGDIRYLAVDAIVNAANSELLGCFIPNHGCIDNAIHTFAGSRLRLACQAIMTEQGRKEAIGQAKLTSAYHLPASYIIHTVGPRITKGHHVSPIRADLLARCYRSSLDLAVKAGLTSLAFCSISTGEFGFPKKEAAQIAIKTVLKWQAEHPESKTLTIIFNTFTSEDKALYDTYLQKENNCE
What is the function of this protein?
ADP-ribose glycohydrolase that hydrolyzes ADP-ribosyl-cysteine bonds (By similarity).  Specifically reverses the SirTM-mediated mono-ADP-ribosylation of GcvH-L, by releasing ADP-ribose from the target protein.  May be involved in the modulation of the response to host-derived oxidative stress.
What are the official names of this protein?
Protein-ADP-ribose hydrolase, SpyMacroD.
Protein: ZN470_HUMAN
Sequence: MKSQEEVEVAGIKLCKAMSLGSVTFTDVAIDFSQDEWEWLNLAQRSLYKKVMLENYRNLVSVGLCISKPDVISLLEQEKDPWVIKGGMNRGLCPDLECVWVTKSLSLNQDIYEEKLPPAIIMERLKSYDLECSTLGKNWKCEDLFERELVNQKTHFRQETITHIDTLIEKRDHSNKSGTVFHLNTLSYIKQIFPMEERIFNFHTDKKSLKTHSVVKKHKQDRGEKKLLKCNDCEKIFSKISTLTLHQRIHTGEKPYECIECGKAFSQSAHLAQHQRIHTGEKPFECTECGKAFSQNAHLVQHQRVHTGEKPYQCKQCNKAFSQLAHLAQHQRVHTGEKPYECIECGKAFSDCSSLAHHRRIHTGKRPYECIDCGKAFRQNASLIRHRRYYHTGEKPFDCIDCGKAFTDHIGLIQHKRTHTGERPYKCNVCGKAFSHGSSLTVHQRIHTGEKPYECNICEKAFSHRGSLTLHQRVHTGEKPYECKECGKAFRQSTHLAHHQRIHTGEKPYECKECSKTFSQNAHLAQHQKIHTGEKPYECKECGKAFSQIAHLVQHQRVHTGEKPYECIECGKAFSDGSYLVQHQRLHSGKRPYECLECGKAFRQRASLICHQRCHTGEKPYECNVCGKAFSHRKSLTLHQRIHTGEKPYECKECSKAFSQVAHLTLHKRIHTGERPYECKECGKAFRQSVHLAHHQRIHTGESSVILSSALPYHQVL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 470, Chondrogenesis zinc finger protein 1, CZF-1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS12_MAGSA
Sequence: MPTINQLIRKPRQPVAARNKVPAMEACPQKRGVCTRVYTTTPKKPNSALRKVARVRLTNGFEVTSYIPGEGHNLQEHSVVMIRGGRVKDLPGVRYHIIRGTLDTQGVKDRRQRRSKYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: DNLJ_SHEPA
Sequence: MPAIQNEIAQLTAELNQHNYRYYVDDSPSIPDAEYDRLLNRLKALETEHPEFCRPDSPTQRVGGEALAKFEQIKHLKPMLSLDNVFDEQEFTAFNQRIVDKTGKDLSYCCEPKLDGLAVSIVYRDGVFERAATRGDGQTGEDITENVRTIKSIPLTLRGDNFPPLVEVRGEVIMPHKAFDALNERARVKGDKLFVNPRNAAAGSLRQLDSKITASRALGFYAYALGVVEPETWELADSHYGQLEQLRSWGVPVSQEVRGCETVAEVMAYYYDIQQRRSSLEFEIDGVVVKVNQIAHQLSLGFVAKAPRWATAFKFPAQEEMTLLEGVDFQVGRTGAVTPVARLKPVFVGGVTVSNATLHNADEIARLGVKVGDTIIIRRAGDVIPQIVAVVAEKRPDDAKDIVFPAHCPVCDSEVERVEGEAVTRCTGGLFCEAQRKEAIKHFASRKALDIDGMGDKVVEQLIDKELVESPADLFRLTASAMTMLERMGMKSATKLVAAIEVAKQTTFARFLYALGIREVGEATAANLAAYFKTLEALKAASAEEFIKVDDVGTIVAAHLAHFLAQPHNLEVIDKLVEAGIHWPAVEEVAEEDLSLKGQTWVLTGTLTQLNRNDAKAKLQALGAKVAGSVSKNTDCLVAGAAAGSKLTKAQELGVKVIDEEALIAILS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: SM34A_HUMAN
Sequence: MEWAKWTPHEASNQTQASTLLGLLLGDHTEGRNDTNSTRALKVPDGTSAAWYILTIIGIYAVIFVFRLASNILRKNDKSLEDVYYSNLTSELKMTGLQGKVAKCSTLSISNRAVLQPCQAHLGAKGGSSGPQTATPETP
What are the official names of this protein?
Small integral membrane protein 34.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NDHI_LOTJA
Sequence: MFLMVTGFMNYSQQTVRAARYIGQSFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETNIRKKRLLNYSIDFGICIFCGNCIEYCPTNCLSMTEEYELSAYDRHELNYNQIALGRLPMSVIDDYTIRTIQIK
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: MINC_ECOL5
Sequence: MSNTPIELKGSSFTLSVVHLHEAEPKVIHQALEDKIAQAPAFLKHAPVVLNVSALEAPVNWSAMHKAVSATGLRVIGVSGCKDAQLKAEIEKMGLPILTEGKEKAPRPAPAPQAPAQNTTPVTKTRLIDTPVRSGQRIYAPQCDLIVTSHVSAGAELIADGNIHVYGMMRGRALAGASGDRETQIFCTNLMAELVSIAGEYWLSDQIPAEFYGKAARLQLVENALTVQPLN
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: RNPA_CHLTR
Sequence: MSRLTLPKNARLLKRKQFVYVQRNGRCCRADQVTLRVVPSRHSNTRKVGITVSKKFGKAHQRNRFKRIVREAFRHVRPNLPGCQVVISPRGNSQPDFLKLSEELLQRIPEALPLASSSRC
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: RS21_SHESM
Sequence: MPIIKVRENEPFDVALRRFKRSCEKAGILADVRAREFYEKPTTARKRAKAAAVKRLAKKLSRENARRVRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: CHCB2_ANTPO
Sequence: IGREAIVGAGLQGPFGGPWPYDALSPFDMPYGPALPAMSCGAGSFGPSSGFAPAAAYGGGLAVTSSSPISPTGLSVTSENTIEGVVAVTGQLPFLGAVVTDGIFPTVGAGDVWYGCGDGAVGIVAETPFASTSVNPAYGYGGAIGGGVPYNSYGPIGYGGCGYNALY
What is the function of this protein?
This protein is one of many from the eggshell of the silk moth.
What are the official names of this protein?
Chorion class CB protein PC404.
What is the protein family that this protein belongs to?
Belongs to the chorion protein family.
Protein: PSBK_LACSA
Sequence: MLNIFSLICLNSALYPSSLFFAKLPEAYAFLNPIVDVMPVIPLFFFLLAFVWQAAVSFR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: AROE_VIBCH
Sequence: MASQIDQYAVFGNPINHSKSPFIHTLFARQTQQSMIYTAQCVPVDGFTEAAKHFFAQGGRGCNVTVPFKEEAYRFADRLTERARLAGAVNTLKKLDDGEILGDNTDGEGLVQDLLAQQVLLKGATILLIGAGGAARGVLKPLLDQQPASITVTNRTFAKAEQLAELVAAYGEVKAQAFEQLKQSYDVIINSTSASLDGELPAIDPVIFSSRSVCYDMMYGKGYTVFNQWARQHGCAQAIDGLGMLVGQAAESFMLWRGLRPGTKQILRELRKNLEGAL
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: SSUB2_PARDP
Sequence: MATQLHRSLKTPAAVAVRGLSRAFGPRRVIDNLDLAIRPGEFVALLGASGCGKSTLLRILGDLDPEFEGEVVVPSRRAIAFQAPRLMPWKRVWHNVVLGLPGRPDRKRAERALDEVGIGHRADVWPKVLSGGEAQRAALARALVREPDLLLLDEPFAALDALTRIKAQALVAELWQRHGCAILLVTHDVEEAILLADRVLVMKEGVIAHHEPIALDRPRDVADPEFARIRGALLDWLGVAHGAAH
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CNTP5_CHICK
Sequence: MDSPALGAVALLLAGFWHLGLTATNYNCDGALVSTLPSSAFTSSSEFFSTHSPSFAKLNRRDGAGGWSPLDSNEQQWLQVDLGDRVEIVGVATQGRYGSSDWVTSYTLMFSDTGRNWKQYRKDDTVWVFTGNSNADSVVHHKLLHSMKARFLRFVPLKWNVGGHIGLRVEVFGCSYKSDIADFDGRSSLLYRFNQKLMSTFKDVVSLKFKSMQEDGVLFHGEGQRGDYITLELQKGKLSLHINLGDSNLHFTNSHTSVTLGSLLDDQHWHSVLIERFNKQVNFTVDKHTQHFRTKGDSDHLDIDYELSFGGIPVPGKPGTFQRKNFHGCIENLYYNGVNIIDLAKRRKPQIYTGNVTFSCSEPQIVPITFVSSSRSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSENSGSLLVYLHGGRLTLLIQKVAEDPVEISEGTNLHDGLWHSLNINARRHRITLTLDNNAATASHATTVSRIYSGNSYYFGGCPDNFTDSQCLNPITAFQGCMRLIFIDNQPKDLILVQQGSLGNFSDLHIDLCDIKDRCLPNYCEHGGKCSQSWTTFYCDCNDTSYMGATCHNSIYEQSCEAYRHQGKTSDFFYIDSDGSGPLGPLRVFCNITEDKIWTAVQHNNTGLTRVQGAGPEKPYTMSFNYNSSAEQLEAVINSAEYCEQEAAYHCKKSRLLNTPNGIPFAWWVGRANEKHLYWGGSLPGIQQCACGLEESCLDMRYFCNCDADREEWTNDTGLLAFKDHLPVTQIVITDTNRSNSEAAWKIGPLHCYGDRQFWNAASFNTEASYLHFPTFHAEVSADISFFFKTTSLSGVFLENLGMKDFIRVEIRSPKEITFSIDVGNGPTEATVQSPTPLNDNQWHYVRAERNLKQTSLQVDNLPKKVLEAPAEGHFRLQLNSQLFVGGTASRQKGFLGCIRSLHLNGQKLDLEERAKMTPGVKPGCPGHCSSYGNLCHNGGKCVEKYNGYSCDCTSSAYEGPFCKEEVSALFEAGTSITYIFQEPYPVTKNASTSSSAIYADAITSKENIAFSFLTAHAPSLLLYINTYFHEYLAVILSKNGSLQVRYKLSKDGLLIFTIDSGNFANREMHHVKINREGRELIIQVDQVIKLKHNFSEIDFKAIKSLTLGKVTDSLPLDPEVSKANAYGFTGCMSSVWYNHVAPLKAALRHPSIAPVTVKGSLTESSCSSLMETDVNTATTIYSSSDPFGKTDEREPLTNAVRSDSAVIGGVIAVVIFIIFCIIAIMSRFLYQHKQAHRSSQTKEKEYPENLESSFKADIDLQNTVSECKREYFI
What is the function of this protein?
May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication.
What are the official names of this protein?
Contactin-associated protein-like 5, Cell recognition molecule Caspr5.
What is the protein family that this protein belongs to?
Belongs to the neurexin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PYRH_METAR
Sequence: MKIVVKVGGSAIVQGLDAQRFKDYADVIKQLAEDHTILIVIGGGTPARDYINVSKQLGANNSILDYIGIGVSRLNARLLISALGDIAYPEPPYDYKDAGLAMYSGKVVVMGGVVPGQTTDAVAAILAEYVHADLLIRTTSVDGVFTADPKLDPKATKIDSMTPQELVDMVTKIEMTAGANNIFDPLGAQIVKRSRIPTVVVNGKQPENLIKAVKGEPIGTIIKE
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CITE2_MOUSE
Sequence: MADHMMAMNHGRFPDGTNGLHHHPAHRMGMGQFPSPHHHQQQQPQHAFNALMGEHIHYGAGNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVASQGGSLPASMQLQKLNNQYFNHHPYPHNHYMPDLHPTAGHQMNGTNQHFRDCNPKHSGGSSTPGGAGGSGTPGGSGGTSGGAGGSSAGGSGGGSTMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEMGLDRIKELPELWLGQNEFDFMTDFVCKQQPSRVSC
What is the function of this protein?
Transcriptional coactivator of the p300/CBP-mediated transcription complex.  Acts as a bridge, linking TFAP2 transcription factors and the p300/CBP transcriptional coactivator complex in order to stimulate TFAP2-mediated transcriptional activation.  Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex.  Stimulates the peroxisome proliferator-activated receptors PPARA transcriptional activity.  Enhances estrogen-dependent transactivation mediated by estrogen receptors.  Acts also as a transcriptional corepressor; interferes with the binding of the transcription factors HIF1A or STAT2 and the p300/CBP transcriptional coactivator complex.  Participates in sex determination and early gonad development by stimulating transcription activation of SRY.  Plays a role in controlling left-right patterning during embryogenesis; potentiates transcriptional activation of NODAL-mediated gene transcription in the left lateral plate mesoderm (LPM).  Plays an essential role in differentiation of the adrenal cortex from the adrenogonadal primordium (AGP); stimulates WT1-mediated transcription activation thereby up-regulating the nuclear hormone receptor NR5A1 promoter activity.  Associates with chromatin to the PITX2 P1 promoter region.
What are the official names of this protein?
Cbp/p300-interacting transactivator 2, MSG-related protein 1, MRG-1, P35srj.
What is the protein family that this protein belongs to?
Belongs to the CITED family.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes with EP300 in dot-like structures.
Protein: SYT_ANASK
Sequence: MSDLVKVTLPDGSQKEAPRGTPVIDFVKGQIGPGLAKAAYFARLDGEPVDLSRAIERDARLEIVTTRSPEALEVARHDAAHVMASVVQKLYPGTQVTIGPAIEDGFYYDFARETPFTPEDLERIEKATNEAIKADLPFVRSEISMEAALALFEGMGERYKVEIVKDIAAKGAKTLTLYKHGDWVDFCLGPHGPSTGRIGVVKLLNVAGAYWRGDAKNAMLQRIYGTAFFDKKELDAHLAKLEEVKKRDHRRLGPQLGLFTFHEFAPGAPFWLPAGTVLYNVLEDAMRRLVLKNGYQEVKTPLLFNKRLWETSGHWGKYRENMFLVVDSESDPALPLEDRCSFSLKPMNCPSHHLIYRMDKRSYRELPVRYFTTDALHRNEASGSLGGLTRVRQFEQDDAHIYLREEQVTDEVLRIFELMKVVYGAFGLGFEATFSTRPEQRIGDDALWDRAEALLRKSLDATGLKWTLNAGDGAFYGPKIDMLVTDSLGRKWQTCTIQLDYAAPERFDLTFVGEDNKEHRPVVIHRAIYGSFERFVAILVEHYAGAFPAWLAPVQARVVTVSDRFEAWAREAGEALQARGWRVEVDASSDKLGAKIRNAQLAKIPFTLVVGEKEVEAKGVSPRRHGGEDLKTMPLEAFAELMTREATAPF
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_CAMC5
Sequence: MKEIIKSEIFKILGRDFVLEKPKDKSLAHYATPLAFSLAKELKKSPVAIANELACKFENSKIFEVSAVNGYLNFKLKGEFLDEISKDALKNGDKFASGKARQDGSTFIEYISANPTGPLHIGHVRGAVYGDTLARIGTHLGYKIFTEYYINDAGNQIDLLGTSISLAARDVLFHENVEYPQKYYRGEYIVDIANEALKKFGKEIFYDEARNLELAEFGKDIVLDIIKKDLAGVGISIQGWASEKALYKELEPTIEKLKRSNQMYEKEGATYIASTTLGDDNDRVVVRNDGRPTYLAGDIIYHNDKFERNYDHYINIWGADHHGYIARLKAAIHFLGYDENRLEIILMQMVSLLKDGKPYKMSKRAGNAVLMSDIVEEIGSDALRFIFISKANTSSLEFDIDELKKEDSSNPIFYINYAHARVNQIFAKAGKSVSDVLDASLENLDDNAKNLLFEALILPEILEDAFASRQLQKVSDYLKSLAASFHKFYNENRVIGSANEESLLKLFAVVALSLRTALSLIGITAKDRM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.