PharMolix/UniProtQA huggingface dataset:
Protein: Y1384_LEPIC
Sequence: MSQFSVLNVGFGNIVLVSKIVSIIHSDSASAKRIRNEAKSNNSLIDATQGKKTRSIIVTDSNHLILSNLRVESLTKRIESRDNSIASEEEDLD
What are the official names of this protein?
Putative regulatory protein LIC_11384.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: RIMP_ECO81
Sequence: MSTLEQKLTEMITAPVEALGFELVGIEFIRGRTSTLRIYIDSEDGINVDDCADVSHQVSAVLDVEDPITVAYNLEVSSPGLDRPLFTAEHYARFVGEEVTLVLRMAVQNRRKWQGVIKAVDGEMITVTVEGKDEVFALSNIQKANLVPHF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMO_PICAN
Sequence: MERLRQIASQATAASAAPARPAHPLDPLSTAEIKAATNTVKSYFAGKKISFNTVTLREPARKAYIQWKEQGGPLPPRLAYYVILEAGKPGVKEGLVDLASLSVIETRALETVQPILTVEDLCSTEEVIRNDPAVIEQCVLSGIPANEMHKVYCDPWTIGYDERWGTGKRLQQALVYYRSDEDDSQYSHPLDFCPIVDTEEKKVIFIDIPNRRRKVSKHKHANFYPKHMIEKVGAMRPEAPPINVTQPEGVSFKMTGNVMEWSNFKFHIGFNYREGIVLSDVSYNDHGNVRPIFHRISLSEMIVPYGSPEFPHQRKHALDIGEYGAGYMTNPLSLGCDCKGVIHYLDAHFSDRAGDPITVKNAVCIHEEDDGLLFKHSDFRDNFATSLVTRATKLVVSQIFTAANYEYCLYWVFMQDGAIRLDIRLTGILNTYILGDDEEAGPWGTRVYPNVNAHNHQHLFSLRIDPRIDGDGNSAAACDAKSSPYPLGSPENMYGNAFYSEKTTFKTVKDSLTNYESATGRSWDIFNPNKVNPYSGKPPSYKLVSTQCPPLLAKEGSLVAKRAPWASHSVNVVPYKDNRLYPSGDHVPQWSGDGVRGMREWIGDGSENIDNTDILFFHTFGITHFPAPEDFPLMPAEPITLMLRPRHFFTENPGLDIQPSYAMTTSEAKRAVHKETKDKTSRLAFEGSCCGK
What are the official names of this protein?
Peroxisomal primary amine oxidase, Copper amine oxidase, Methylamine oxidase.
What is the protein family that this protein belongs to?
Belongs to the copper/topaquinone oxidase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: SSL13_STAAE
Sequence: MNNNITKKIILSTTLLLLGTASTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYLTFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDSFALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIRQTLIKSKKLYNNSYNKGQIKITGADNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKSN
What is the function of this protein?
Acts as a pathogen alarming molecule by acting on host neutrophil chemotactic factors FPR2.  Plays a role of chemoattractant and induces degranulation and oxidative burst in neutrophils.
What are the official names of this protein?
Superantigen-like protein 13.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal/streptococcal toxin family.
Protein: THNB_TRIHA
Sequence: MSGDYSATRKSENVDTSTTASQEDSSLAPEQPEKLVGASDVAAVSNNEPTADEYPHGLRLITLVLAINLAMFLASLDQTILGTAIPKITDEFHGLSQVSWYGSAYFMCLGGFQSTWGKVYKYFPLKISFAIAVFVFELGSLICGVARNSNTFIVGRAIAGIGGAGITSGSTVILAFSAEPAKRPTLMSTMGVTYCIAFILGPLIGGAFSEKVTWRWCFYINLPIGGLAMALFFLFFRTPSVSTTQDATLKEKLLHMDPVGTVLAMGGIISFILALQYAGVSHAWNSSVVIGLLVGFVLIMVTLAAWEYFQGDYAMLPYRLFKRRVMWAGGIFQFFFVGCYFLLLFYLPIYFQSIKGVSAIHSGVDNLPLVLSACLFIILGGAAVEKTHMATPYMTAGSAVAAVATGLLYTLDVDTSSGKWIGYQVLVGAGLAFPFQNALNILQAEVDADDMSPATSSLYFFQILGGAFSISAAQAAFNNRLLHSLTINAPGVSPLLVLATGASDLRSVFSADELPGVILSYMDGLKAAFAVSVGLVGMAFLSSLHMVMIDSCETLHTTGDDGAWKGKEVKELEVERLYVN
What is the function of this protein?
MFS-type transporter; part of the gene cluster that produces the tetronate natural products trihazones.
What are the official names of this protein?
MFS-type transporter thnB, Trihazone biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PP1R7_HUMAN
Sequence: MAAERGAGQQQSQEMMEVDRRVESEESGDEEGKKHSSGIVADLSEQSLKDGEERGEEDPEEEHELPVDMETINLDRDAEDVDLNHYRIGKIEGFEVLKKVKTLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIENLEALTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLESWSDLDELKGARSLETVYLERNPLQKDPQYRRKVMLALPSVRQIDATFVRF
What is the function of this protein?
Regulatory subunit of protein phosphatase 1.
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 7, Protein phosphatase 1 regulatory subunit 22.
What is the protein family that this protein belongs to?
Belongs to the SDS22 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLYCO_PIRYV
Sequence: MDLFPILVVVLMTDTVLGKFQIVFPDQNELEWRPVVGDSRHCPQSSEMQFDGSRSQTILTGKAPVGITPSKSDGFICHAAKWVTTCDFRWYGPKYITHSIHHLRPTTSDCETALQRYKDGSLINLGFPPESCGYATVTDSEAMLVQVTPHHVGVDDYRGHWIDPLFPGGECSTNFCDTVHNSSVWIPKSQKTDICAQSFKNIKMTASYPSEGALVSDRFAFHSAYHPNMPGSTVCIMDFCEQKGLRFTNGEWMGLNVEQSIREKKISAIFPNCVAGTEIRATLESEGARTLTWETQRMLDYSLCQNTWDKVSRKEPLSPLDLSYLSPRAPGKGMAYTVINGTLHSAHAKYIRTWIDYGEMKEIKGGRGEYSKAPELLWSQWFDFGPFKIGPNGLLHTGKTFKFPLYLIGAGIIDEDLHELDEAAPIDHPQMPDAKSVLPEDEEIFFGDTGVSKNPIELIQGWFSNWRESVMAIVGIVLLIVVTFLAIKTVRVLNCLWRPRKKRIVRQEVDVESRLNHFEMRGFPEYVKR
What is the function of this protein?
Attaches the virus to host cellular receptor, inducing endocytosis of the virion.  In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane (By similarity).
What are the official names of this protein?
Glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the vesiculovirus glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein.
Protein: TACY_BACCE
Sequence: MKNFKGRKFLTCVLVSLCTLNYSSISFAETQAGHANDITKNASSIDTGIGNLTYNNQEVLAVNGDKVESFVPKESINSNGKFVVVDVRKNHLQRHQSIFRLLDSVANRTYPGAVQLANKAFADNQPSLLVAKRKPLNISIDLPGMRKENTITVQNPTYGNVAGAVDDLVSTWNEKYSATHTLPARMQYTESMVYSKAQIASALNVNAKYLDNSLNIDFNAVANGEKKVMVAAYKQIFYTVSAELPNNPSDLFDNSVTFGELTRKGVSNSAPPVMVSNVAYGRTVYVKLETTSKSKDVQAAFKALLKNNSVETSGQYKDIFEESTFTAVVLGGDAKEHNKVVTKDFNEIRNIIKDNAELSFKNPAYPISYTSTFLKDNATAAVHNNTDYIETTTTEYSSAKMTLDHYGAYVAQFDVSWDGFTFDQNGKEILTHKTWEGSGKDKTAHYSTVIPLPPNSKNIKIVARECTGLAWEWWRTIIKMNKMFH
What is the function of this protein?
A cholesterol-dependent toxin with hemolytic activity against host red blood cells.  Causes cytolysis by forming pores in cholesterol containing host membranes.  binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex.  Cholesterol is required for binding to host membranes, membrane insertion and pore formation; cholesterol binding is mediated by a Thr-Leu pair in the C-terminus.  Can be reversibly inactivated by oxidation.
What are the official names of this protein?
Hemolysin.
What is the protein family that this protein belongs to?
Belongs to the cholesterol-dependent cytolysin family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane; Multi-pass membrane protein. Note=Secreted as soluble protein that then inserts into the host cell membrane and forms pores formed by transmembrane beta-strands.
Protein: FTSH2_CONWI
Sequence: MTDEPQSDEQQTTEQERPLGTKRATRADGLRRPGVRSGLAERRSPAADSVRNGAAAVRRFLLRDVFALGLMIAALVIVILFFTLLGATKPTSSGTGIPLSQVFTLARDRAIVEATLLDEDARVQVHTRDGAEYWAAYPSSGAQTATLSSALERGGAIVAVKQQPGKAQVTIVVQFLLPILLLVCLFALFMRIGQDGGAGGIASFSNFTGRGRKKGKGTAHRVTFADIAGVPEAVAELAEIRDYLDDPSRYLDLGAAAPKGVLLVGPPGTGKTLLAKAVAGEADAAFFSLSGSDFVESLVGVGAARVRDLFAKARRMSPAIIFIDEFDAAGRKRGAGIGQGNDEREQTLNQLLVEMDGFSGDGGLVVMGATNRPDILDPALLRPGRFDRQITVDTPDVHGRSEILRLHGSKRPMAPDADLDEIARLTPGFSGAELANVVNEAALLTVRGGRREISQKLLEESIDRVVAGPAKKHLLTERERWIISIHESSHAVVTEAMGTGATARKVSIVARGRSLGTAAHMLTDRDQTIMEEPDLVMQLIAMLAGAAGERIEFGHLSTGVHDDLHEATSLARSMVTSFGMSDELGPVTIGEKSGEVFLGASLQDLGAVGPKTLDLIDDAVERLVKDAELVARAILRINIDAVHETAHALLEHETLSGVALEAVLSTVTTVEPEHFPELRERERGSARDRDA
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH 2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: SURE_SHEDO
Sequence: MINILVSNDDGVQAEGIRCLTEALSAFATVLTVAPDRNCSGASNSLTLTNPLRINNLDNGFVAVNGTPSDCVHLAIRELCEQEPDIVVSGINAGANMGDDTLYSGTVAAAMEGRFLGLPAIAVSLAGKELLHYQTAAYFSAKIVQGLLAHPLAKDQILNVNVPDLPIEAIKGIKVTRLGARHKAEGMVKTQDPAGREIFWLGPVGKEQDAGEGTDFDAISQGYVSITPLTVDLTAYNQLAGLEHWIKIL
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POLS_ABPVR
Sequence: ADQETNTSNVHNTQLASTSEENSVETEQITTFHDVETPNRINTPMAQDTSSARSMDDTHSIIQFLQRPVLIDHIEVIAGSTADDNKPLNRYVLNRQNPQPFVKSWTLPSVVLSAGGKGQKLANFKYLRCDVKVKIVLNANPFIAGRLYLAYSPYDDRVDPARSILNTSRAGVTGYPGIEIDFQLDNSVEMTIPYASFQEAYDLVTGTEDFVKLYLFTITPILSPTSTSASSKVDLSVYMWLDNISLVIPTYRVNTSIVPNVGTVVQTVQNMTTRDSETIRKAMVALRKNNKSTYDYIVQALSSAVPEVKNVTMQINSKKNNSNKMATPVKEKTKNIPKPKTENPKIGPISELATGVNKVANGIERIPVIGEMAKPVTSTIKWVADKIGSVAAIFGWSKPRNLEQVNLYQNVPGWGYSLYKGIDNSVPLAFDPNNELGDLRDVFPSGVDEMAIGYVCGNPAVKHVLSWNTTDKVQAPISNGDDWGGVIPVGMPCYSKIIRTTENDTTRTNTEIMDPAPCEYVCNMFSYWRATMCYRIAIVKTAFHTGRLGIFFGPGKIPITTTKDNISPDLTQLDGIKAPSDNNYKYILDLTNDTEITIRVPFVSNKMFMKSTGIYGGNSENNWDFSESFTGFLCIRPITKFMCPETVSNNVSIVVWKWAEDVVVVEPKPLLSGPTQVFQPPVTSADSINTIDASMQINLANKADENVVTFFDSDDAEERNMEALLKGSGEQIMNLRSLLRTFRTISENWNLPPNTKTAITDLTDVADKEGRDYMSYLSYIYRFYRGGRRYKFFNTTALKQSQTCYVRSFLIPRYYTADNTNNDGPSHITYPVLNPVHEVEVPYYCQYRKLPVASTTDKGYDASLMYYSNVGTNQIVARAGNDDFTFGWLIGTPQTQGITRTETK
What is the function of this protein?
Forms, together with protein VP1 and protein VP2, an icosahedral capsid protecting the viral RNA genome.  The icosahedral capsid has a pseudo-T=3 symmetry with a diameter of approximately 300 Angstroms, and is composed of 60 copies of each capsid proteins.
What are the official names of this protein?
Structural polyprotein.
What is the protein family that this protein belongs to?
Belongs to the picornaviruses polyprotein family.
What are the subcellular locations of this protein?
[Protein VP1]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Protein VP2]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Protein VP3]: Virion. Host cytoplasm.
Protein: B2MG_MELGA
Sequence: DLTPKVQVYSRFPASAGTKNVLNCFAAGFHPPKISITLMKDGVPMEGAQYSDMSFNDDWSFQRLVYADFTPSSDAVYTCKVDHETLKEPQVYKWDPEF
What is the function of this protein?
Component of the class I major histocompatibility complex (MHC).  Involved in the presentation of peptide antigens to the immune system (By similarity).
What are the official names of this protein?
Beta-2-microglobulin.
What is the protein family that this protein belongs to?
Belongs to the beta-2-microglobulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPH_BUCAT
Sequence: MNIILTNPRGFCAGVKRAILIVENALKVYKKTIYIRHELVHNQYVINTLRQKGVVFVEKIEQIPDYSVVIFSAHGVSKKVVQEAVKKKLIILDATCPLVEKVHIEVSKSSEKAIETILIGHRGHPEVEGTIGQYNNKNGKIYLVESIEDVHNLSVQNSKKLNFFTQTTLSITNTKKIIAALKNKFPEISGPNKEDICYATTNRQIAVRQLSKIADIIFVIGSNNSSNSNRLAELGKETGTFTKLISSFLDIKKKWLKNVNYIGITAGASAPEILVTEVIQYLRKIGAHKPIEMIGVREKKIFKIPKKLLNIKTILDENG
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: RSMA_ROSDO
Sequence: MSTIDHLPPLRSVIRDHDLSARKSMGQNFLLDLNLTAKIARQAGDLSACDVLEIGPGPGGLTRGLLAQGARRVLAIEKDARCLPALAEIAAVYPGRLEVMNGDALEIDPLSALTPPIRVAANLPYNVGTELLVRWLTPQIWPPYWQSLTLMFQREVAERIVARPGSKAYGRLAILAQWRADARIVMQLPPDAFTPPPKVSSSVVQITALPAPRYPADPYVLSKVVAMAFNQRRKMLRAALKGLGPDIEDRLLAAGIEPTERAERVSLEGFCALARAVAAT
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_PROM0
Sequence: MPTISQLVGSERKRLTKKTKSPALKSCPERRGVCTRVYTSTPKKPNSALRKVARVRLTSGFEVTAYIPGIGHNLQEHSVVLLRGGRVKDLPGVRYHIIRGTLDTAGVKDRRQSRSKYGAKAPKD
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: EXO5_VANPO
Sequence: MLRCRSSINILQLHSRFHTHEIIISSKESEARTRITDEERLVIKRFPIFKNDSSYILPSSNKLTKVKKEHIALKIHKIKKLFGEDPNNVGYLNYHLPKSYPVPFEINNRAYDNSDGNGENEKVRNRLSVTKLLTKRWCELREAYDIYSETPLFEHKQIIEGKLVHQKLEEDIHPVTEDLESFVEDFEVPIPTDNFHNHVDDLFSCSMRLLSLFRCGEAREVRCHAFLDSRTGTFIDGLPKDGKDVLVSGIIDHLSLRRKIRVFTSSGFTEFNGLNDEVFENGNNFQSIIEWLNANIDFLKSEYQINVSDVKTRMFRSVVSQKSVLKYSKYQVMYYRYFLELLGLHPDVTYGQLLNSSLSRGFNIDQRIDPAKVIYFMASDEVIVDDMRKLRDGDDIGFPPFDSDFTGSSPTEEEYDMSILSDQITDPNVLERYGEFLVPWKRPVTLKYFAARLAQMYNCISPLLSKHLTLEYYYKGDNFKNINFDFNEDEIRNGAFDSSMFWFGKRDIEPIEPTSENLITYCKYCDYVNVCSWRQKATQQKKELGPRLLKLNQN
What is the function of this protein?
Single strand DNA specific 5'exonuclease involved in mitochondrial DNA replication and recombination.  Releases dinucleotides as main products of catalysis.  Has the capacity to slide across 5'double-stranded DNA or 5'RNA sequences and resumes cutting two nucleotides downstream of the double-stranded-to-single-stranded junction or RNA-to-DNA junction, respectively (By similarity).
What are the official names of this protein?
Exonuclease V, mitochondrial, Exo V, Defects in morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the EXO5 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: HEMA_I78A4
Sequence: MKTIIVLSCFFCLAFSQDLSENNNNTATLCLGHHAVPNGTIVKTITDDQIEVTNATELVQSSSTGKICNNPHRILDGRDCTLIDALLGDPHCDVFQDETWDLYVERSKSFSNCYPYDVPDYASLRSLVASSGTLEFITEAFTWTGVTQNGGSGACKRGPGNGFFSRLNWLTKSGSAYPVLNVTMPNNDNFDKLYVWGVHHPSTNQEQTNLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRGQSRRISIYWTIVKPGDILVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKITYGACPKYIKQSTLKLATGMRNVPEKQTRGLFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNADVLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEDMGNGCFKIYHKCDNACIESIRNGTYDHDIYRDEALNNRFQIKGCGVKSGYKDWILWISFAISCFLLCVVLLGFIMWACQRGNIRCNICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: PUR9_STRPB
Sequence: MTKRALISVSDKSGIVDFAKELKNLGWDIISTGGTKVALDNAGVETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDADSHLQAAKDNNIELIDLVVVNLYPFKETILRPDITYDLAVENIDIGGPSMLRSAAKNHASVTVVVDPADYATVLGELADAGQTTFETRQRLAAKVFRHTAAYDALIAEYFTTQVGEAKPEKLTITYDLKQAMRYGENPQQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDRPTVVVLKHMNPCGIGQADDIETAWDYAYEADPVSIFGGIVVLNREVDAATAKKMHPIFLEIIIAPSYSEEALAILTNKKKNLRILELPFDAQAASEVEAEYTGVVGGLLVQNQDVVAENPSDWQVVTDRQPTEQEATALEFAWKAIKYVKSNGIIITNDHMTLGLGAGQTNRVGSVKIAIEQAKDHLDGAVLASDAFFPFADNIEEIAAAGIKAIIQPGGSVRDQDSIDAANKHGLTMIFTGVRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: DAPA_LACLA
Sequence: MSAKETIEKLQNARIITALVTPFKENGQINFGAFPKLIEDLLANHTEGLILAGTTAESPTLTHDEELAIFAAVNKIVDGRIPLIAGVGTNDTRDSVEFVKEVAELGYIDAGLAVTPYYNKPSQEGIYQHFKAIATASDLPIILYNIPGRVVTEIQVETILRLAELENVIAIKECTNTDNLAYLIEKLPKDFLVYTGEDGLAFHTKALGGQGVISVASHILGQEFFEMFAEIDQGSIQKAAAIQRKILPKINALFSVTSPAPIKTVLNAKGYEVGGLRLPLVACTTEESKIILEKIGN
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS8_RHOP5
Sequence: MSRPVPNPGILDIAPYTPGKSPVAQPGRKVFKLSANETPFGPSPHAIAAYQSAADHLEDYPEGTSRVLREAIGKTFGLDPDRIICGAGSDEILNLLAHTYLAPGDEAIATTYGFLVYPIATMANGAKLVIAEEKNLTCDVDAILAKVSPNTKLVWLANPNNPTGTYIPFDEVRRLRAGLPEHVVLVLDGAYADYVAKNDYETGIELVSTTENTVVCHTFSKIHGLAALRIGWMFGPANIVDAVNRIRGPFNTSVPAQLAAVAAIKDTAHVEMSRAHTIQWRDRLTEEFTKLGLTVTPSVCNFVLMHFPQTAGKTAAEADAFLTQRGLVLRGLNNYGLPHALRMTIGTDEANELVIAALREFMAQP
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: GUN_ECO57
Sequence: MNVLRSGLVTMLLLAAFSVQAACTWPAWEQFKKDYISQEGRVIDPSDARKITTSEGQSYGMFFALAANDRAAFDNILDWTQNNLAQGSLKERLPAWLWGKKENSKWEVLDSNSASDGDVWMAWSLLEAGRLWKEQRYTDIGSALLKRIAREEVVTVPGLGSMLLPGKVGFAEDNSWRFNPSYLPPTLAQYFTRFGAPWTTLRETNQRLLLETAPKGFSPDWVRYEKDKGWQLKAEKTLISSYDAIRVYMWVGMMPDSDPQKARMLNRFKPMATFTEKNGYPPEKVDVATGKAQGKGPVGFSAAMLPFLQNRDAQAVQRQRVADNFPGSDAYYNYVLTLFGQGWDQHRFRFSTKGELLPDWGQECANSH
What is the function of this protein?
Hydrolyzes carboxymethylcellulose.
What are the official names of this protein?
Endoglucanase, Carboxymethylcellulase, CMCase, Cellulase, Endo-1,4-beta-glucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 8 (cellulase D) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ENGB_YERPA
Sequence: MTIRNYNYHMTHFVISAPDIRHLPRDEGIEVAFAGRSNAGKSSALNTLTNQKGLARTSKTPGRTQLINLFEVVDGVRLVDLPGYGYAEVPEEMKLKWQRALGEYLQKRNCLKGLVVLMDIRHPLKDLDQQMITWAVAVGTPVLLLLTKADKLASGARKAQLNLVREAIIPFMGDIQVEAFSSLKKIGVDKLREKLDTWFSEIPPEVMAEEFDGEGE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: CYNS_POLAQ
Sequence: MDRSVVTQKIIEAKVRNGMKWSDIAKAIGESKEWVTAGCLGQMTFTKVQAEAAGKLFDLTDEEMAWLQIVPYKGSLPTAVPTDPLIYRWYEIVSVYGTTIKELIHEEFGDGIMSAIDFSMDIQREPDPKGDRVQVVLSGKYLSYKTY
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: UN45A_PONAB
Sequence: MTASSVEQLRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACYLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPEEKGTEKKQKASQNLVVLAREDAGAEKTLRSNGVQLLQRLLDTGETDLMLAALRTLVGICSEHQSRTVATLSILGTRRVVSILGVESQSVSLAACHLLQVMFDALKEGVKKGFRGKEGAIIVDPARELKVLISNLLDLLTEVGVSGQGRDNALTLLIKAVPRKSLKDPNNSLTLWVIDQGLKKILEVGGSLQDPPGELAVTANSRMSASILLSKLFDDLKCDAERENFHRLCENYIKSWFEGRGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMEGVIALCASEQEEEQLVAVEALIHAAGKAKRASFITANGVSLLKDLYKRSEKDSIRIRALVGLCKLGSAGGTDFSMKQFAEGSTLKLAKQCRKWLCNDQIDAGTRRWAVEGLAYLTFDADVKEEFVEDAAALKALFQLSRSEERSVLFAVASALVNCTNSYDYEEPDPKMVELAKYAKQHVPEQHPKDKPSFVRARVKKLLAAGVVSAMVYMVKTESPVLTSSCRELLSRIFLALVEEVEDRGTVVAQGGGRALIPLALEGTDVGQTKAAQALAKLTITSNPEMTFPGERIYEVVRPLVSLLHLNCSGLQNFEALMALTNLAGISERLRQKILKEKAVPMIEGYMFEEHEMIRRASTECMCNLAMSKEVQDLFEAEGNDRLKLLVLYSGEDDELLQRAAAGGLAMLTSMRPTLCSRIPQVTTHWLEILQALLLSSNQELQHRGAVVVLNMVEASREIASTLMESEMMEILSVLAKGDHSPVTRAAAACLDKAVEYGLIQPNQDGE
What is the function of this protein?
May act as co-chaperone for HSP90 (Potential).  Prevents the stimulation of HSP90AB1 ATPase activity by AHSA1.  Positive factor in promoting PGR function in the cell (By similarity).  May be necessary for proper folding of myosin (Potential).  Necessary for normal cell proliferation.  Necessary for normal myotube formation and myosin accumulation during muscle cell development.  May play a role in erythropoiesis in stroma cells in the spleen (By similarity).
What are the official names of this protein?
Protein unc-45 homolog A, Unc-45A, Smooth muscle cell-associated protein 1, SMAP-1.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Note=Predominant in the perinuclear region. Little protein in the nucleus (By similarity).
Protein: SPRTL_STAAN
Sequence: MNNDKLQRMVENLSEEKFGRTFRHCAYFNKRLRTTGGRYLLKSHDIEINPKQYEHYGEDAVVKIILHELCHYHLHIAGKGYQHKDQDFKRLSQQVGAPRFCNSIESYQQRANYEYYCTKCHAKYIRIRKVDTNRMRCGHCNGKLRMKRQLK
What are the official names of this protein?
Protein SprT-like.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.