PharMolix/UniProtQA huggingface dataset:
Protein: RBL_BEAGR
Sequence: SVGFKAGVKEYKLTYYTPEYKTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVPGEEDQFIAYVAYPLXLFEEGSVTNMLTSIVGNVFGFKALRALRLEDXRIPTSYIKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALXKAQAETGEIKGHYLNATAGTCEEMYKRAIFARELGAPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAAEGNEIIRXASKXSPELAAACEVWKEIRFNFKAVDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y456_ARCFU
Sequence: MEEAEKAKRRSIELLNETRNCAYSSFVALAEALNISLNEDMKNMAIGFAGGISGSGHICGALWGSIAAASLYTMKMMGDRRKIQNPLERYMPVYAKCAGIYRKFVELNGSPNCGDLNPNLDLVSVEQRRKCMEIVSRAVEITLSSLKDQKT
What are the official names of this protein?
Uncharacterized protein AF_0456.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: COQ10_DROME
Sequence: MLKGSTLKALDVRILWPLIETRSAGKCKLHNPRPTPNRNIAAAKLIVTLRLLLSCCSGGHQRSFSSSTHRSYITFNDFRKKHRWYTKKELVGYSMQDMYSVVSDVSNYHKFVPYVKRSDVHSRGSEGFKADLIVGFPPLNEAYTSQVTLVPPSLVKSECHDGRLFNYLLNEWSFKPGLKDIPNSCVLDFKVSFEFKSLLHSNVANIFFDLICDQMENAFIQEVRRRSGPPSIRSHVLTSDRS
What is the function of this protein?
Required for the function of coenzyme Q in the respiratory chain.  May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes (By similarity).
What are the official names of this protein?
Coenzyme Q-binding protein COQ10, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COQ10 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: DNSL1_CHLAE
Sequence: MHYPTALLFLILVNGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQEVVDSSGSAIPLLLRELNRFDASGPYSTLSSPQLGRTTYVETYVYFYRSHKTQVLSSYVYNDEDDVFAREPFVAQFSLPSDVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQHWQSKDVILLGDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCAYDRIVLHGERCRSLLHTAAAFDFPTTFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLLLLSLLSPQLCPAT
What are the official names of this protein?
Deoxyribonuclease-1-like 1, DNase X, Deoxyribonuclease I-like 1, DNase I-like 1.
What is the protein family that this protein belongs to?
Belongs to the DNase I family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: HBSAG_HBVCJ
Sequence: MGGWSSKPRQGMGTNLSVPNPLGFFPDHQLDPAFGANSNNPDWDFNPNKDHWPEANQVGAGAFGPGFTPPHGGLLGWSPQAQGILTTLPAAPPPASTNRQSGRQPTPISPPLRDSHPQAMQWNSTTFHQALLDPRVRGLYFPAGGSSSGTVNPVPTTASPISSIFSRTGDPAPNMESTTSGFLGPLLVLQAGFFLLTRILTIPQSLDSWWTSLNFLGGAPTCPGQNSQSPTSNHSPTSCPPTCPGYRWMCLRRFIIFLFILLLCLIFLLVLLDYQGMLPVCPLLPGTSTTSTGPCRTCTIPAQGTSMFPSCCCTKPSDGNCTCIPIPSSWAFARFLWEWASVRFSWLSLLVPFVQWFVGLSPTVWLSAIWMMWYWGPSLYNILSPFLPLLPIFFCLWVYI
What is the function of this protein?
The middle envelope protein plays an important role in the budding of the virion.  It is involved in the induction of budding in a nucleocapsid independent way.  In this process the majority of envelope proteins bud to form subviral lipoprotein particles of 22 nm of diameter that do not contain a nucleocapsid.
What are the official names of this protein?
Large envelope protein, L glycoprotein, L-HBsAg, LHB, Large S protein, Large surface protein, Major surface antigen.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus major surface antigen family.
What are the subcellular locations of this protein?
Virion membrane.
Protein: TRMA_PROMH
Sequence: MQNSLPTQTYQSQLNEKTERLQKMMAPFNAPNVEVFSSPEQHYRMRAEFRIWHEQDALYHIMFDQETKQRIRVDQFPVASQLINQMMVALLAEIKDKPTLRHKLFQIDYLSTLSNKIIVSLLYHKKIDETWQQEATALRQTLIAQGFDVQLIGRAYKTKIMLDNDFVDEVLPVAGQQMIYRQVENSFTQPNAQVNIKMLEWALSVTENSTGDLLELYCGNGNFSLALARNFKRVLATEIAKPSVHAAQYNIAMNHIDNVKIIRMSAEDFTQAMNGVREFKRLEGINLQDYQCETIFVDPPRSGLDEKTVELVKNYSRILYISCNPQTLCQNLETLIKTHKISKLALFDQFPYTHHMECGVLLEKR
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: NRFA_PHOPR
Sequence: MSKKWTRNTAAMAAILSALCLSTNALATSEQAVTDENQTTTQQEGMRFEPRNEKFAEAHAEQYKSWKATQESEEIEDALEGDPNMVVLWAGYGFSKDYNKARGHFYAITDVRETLRTGGPTDDKSGPMPMACWSCKSPDVARVIDDRGEDGYFEGKWARLGAEINNAIGCSDCHNTGSEEFAKGGPALQMSRPYAERAMETIGKKFEDQSRFDQQAQVCGQCHVEYYFTGPKKSVKFPWDKGTSVDDMEVYYDEIGFKDWTHGVSKAPMLKAQHPGYETWREGIHGKNNVTCIDCHMPKVQNEDGTVFTDHKVGNPFDRFEDTCAQCHTQTKAALKSVVATRKASVLEMKLRAEKQIIAAHFEAKAAWDAGATEAEMEPILMDIRHAQWRWDYAIASHGVHMHAPEVALRILGTALDKAGDARAKVIRLLATKGITEEIQIPDISTKVKAQQALGMDMNKMNAEKDEFLKTIVPEWDKQADAREAKY
What is the function of this protein?
Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
What are the official names of this protein?
Cytochrome c-552, Ammonia-forming cytochrome c nitrite reductase, Cytochrome c nitrite reductase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c-552 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SYDND_RHOPS
Sequence: MHRYRTHTCGALRDSDIDQTVRLSGWCHRIRDHGGLLFIDLRDHYGLTQCVADPDSPAFKDAEKLRAEWVVRIDGRVRRRPEGTDNDDLPTGKIELFITEIEVLGPAGELPLPVFGEQEYPEDVRLRYRFLDLRREKLHQNIMTRGAIVDAMRARMKQQGFFEFQTPILTASSPEGARDFLVPSRIHPGKFYALPQAPQQYKQLLMMSGFDRYFQIAPCFRDEDPRADRLPGEFYQLDVEMSFVTQDDVFAAMEPVITGVFEDFAKGKRVTKGWPRIPYADSMRKYGTDKPDLRNPIEMQDVSEHFRGSGFKVFARMLEEERNQVWAIPGPGGGSRAFCDRMNSWAQGEGQPGLGYIMWREGGEGAGPLANNIGPERTEAIRAALGLKAGDAAFFVAGDPSKFVKFAGLARTKVGEELNLIDKDQFALAWVVDFPMYEYNEDDKKVDFSHNPFSMPQGGMDALLGQDPLTIKAFQYDITCNGFEIASGGIRNHRPEAMVKAFEIAGYGEQEVVDRFGGMYRAFQYGAPPHGGMAAGVDRIVMLLCGTNNLREISLFPMNQRAEDLLMGAPSQVTPKQLRELHIRLNLPEN
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BDG5_ARATH
Sequence: MITSSFSEKCTSVINGAPSWAVFFLFDLLDYFLCIVFRFLDEVMEEKSESCHCNNPREKTHFAEYEFLSETLYRRRNVFRQAGFLRFANKLPEITKKIGIVTFLRKFLFPHTMNKVSHEVANRWSDCGCKTCVSWINTDKLNVIVKQPSISDLSISNKPVENVIFVHGFLASSSFWTNTVFKYLPETTEGTNYRFFAIDLLGFGDSPKPRASQYSLKEHVEMIEKSVILPNNLTSFHVVAHSMGCIIGIALAAKFSDSVKSVALVAPPYFADSKGGASCAALDVVAKKKLWPPASFFTAMMCWYEHIGRGVCLVFCRHHRTWERIIKIVTWRRKLPTAIMDFTKHTHQSGWHSMHNVICGGAKFTDKHLETLIKSGVKINVMQGDKDVVVPIDCLSNMKGKFPAVEVEVIAGTDHSTVIMSRREVFAANLVSLWATSEKKQKV
What is the function of this protein?
Involved in cuticle development and morphogenesis.
What are the official names of this protein?
Probable lysophospholipase BODYGUARD 5, AtBDG5.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Secreted, cell wall.
Protein: ENO_BURMS
Sequence: MSAIVDIIGREILDSRGNPTVECDVLLESGTMGRAAVPSGASTGSREAIELRDGEAGRYGGKGVLKAVEHINTEISEAIMGLDASEQAFLDKTLLELDGTDNKSRLGANAMLAVSMAVAKAAAEEAGLPLYRYFGGSGAMQLPVPMMNIVNGGAHANNSLDIQEFMIVPVSQPTFREALRCGAEVFHALKKILGDRGMSTAVGDEGGFAPNFGSNDECLSTILQAIEKAGYRAGEDVLLALDCAASEFYHDGKYQLAGEGLQLSSAEFTDYLATLADKFPIVSIEDGMHEGDWDGWKLLTERLGKKVQLVGDDLFVTNTRILKEGIEKGIANSILIKINQIGTLTETFAAIEMAKRARYTAVISHRSGETEDSTIADIAVGLNAGQIKTGSLSRSDRISKYNQLLRIEEDLGDIASYPGKSAFYNLR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: SYE_RHIL3
Sequence: MTVSGTATGVRVRIAPSPTGEPHVGTAYIALFNYLFAKKHGGEFILRIEDTDATRSTPEFETKVLDALKWCGLEWKEGPDIGGPYGPYRQSDRKDMYQPYAQELLEKGHAFRCFCTPARLEQMRETQRAAGKPPKYDGLCLNLAAEEVTSRMAAGETTVIRMKIPTEGSCDFTDGVYGEVSIPWDSVDMQVLVKADGMPTYHMANVIDDHLMKITHVARGEEWLASVPKHILLYRYFGWDQPVFMHLSLMRNADKSKLSKRKNPTSISYYSALGYIPEALMNFLGLFFIQIAEGEELLTMDELSEKFDPENLSKAGAIFDIQKLDWLNGRWIREKLSEEEFQARVLTWAMENDRLKEGLRLSQTRISKLGELPDLAGFLLKSDLGLQPSDFAKIKSPPEEILEILNTVQPDLEKILEWNVETIEAELRAIADRMGKKLKVVVSPLFVAVSGSSRSLPLFDSMAILGRSVVRQRLKLASQAVAALVGSK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_CHRSD
Sequence: MSDVVVVIPARYGASRLPGKPLLDLHGEPMIARVWQRACKSDATRVVIATDDERIEAAMQPYGADVMLTAPDHPSGTDRLAEVAARLELDADTIVVNVQGDEPLLPPALIDQVVRRLADDTTASIATLAEPIGDVETLFNPNVVKVVRDLHGRALYFSRAPVPWDREHFATRPDCLATDAWLRHIGLYAYRAGFLAAYVDWLPSPLEQLEQLEQLRAMHHGHRIQVALAAEAHPAGVDTEADLARVRRLIAEGEGAA
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIR2_VACCA
Sequence: MEPILAPNPNRFVIFPIQYHDIWNMYKKAEASFWTVEEVDISKDINDWNKLTPDEKYFIKHVLAFFAASDGIVNENLAERFCTEVQITEARCFYGFQMAIENIHSEMYSLLIDTYVKDSNEKNYLFNAIETMPCVKKKADWAQKWIHDSAGYGERLIAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLLHPPSEETVRSIITDAVSIEQEFLTAALPVKLIGMNCEMMKTYIEFVADRLISELGFKKIYNVTNPFDFMENISLEGKTNFFEKRVGEYQKMGVMSQEDNHFSLDVDF
What is the function of this protein?
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis.  Allows virus growth in non-dividing cells.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase small chain, Ribonucleotide reductase small subunit, Ribonucleotide reductase subunit 2, RNR2.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
Protein: CMOA_SHEAM
Sequence: MTNQQDTLFAEPGEHQGNFQFDSRVAGVFGDMIRRSVPGYTQIINTIGEIADRCVTPGSNVYDLGCSLGAATLAIRRKIEGRNARIFAIDNSEPMLVRAEENLSAYVSDTKVFFQLADIRDQTFENASLVVLNFTLQFLPPDDRDTLLARIYQGLNPGGILLLSEKLKFDGVDVQALLDSLHLDFKRANGYSELEISQKRSAIENVLIPDTLEQHKTRLNQAGFTQADLWFQCFNFASMVAIK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: FOLD_EHRCR
Sequence: MEENIINGKVIAEDITSTLAVCINDLKVQHNVTPCLIVILVGDDPASHLYVRNKQRKAEMLGLRSETMLLPSTTSESSLIDTIRRLNNDDSVHGILVQLPVPKHIDKNLIINTIDPRKDVDGFHNENVGRLFTGQKKDCLIPCTPRGCLYLIKTVTRNLSGSDAVVIGRSNIVGKPMACLLLGENCTVTTVHSATRNLPDYCSKADVLVAAVGIPHFVKSSWIKPGAIVIDVGINAIEEGGVKKFVGDVDFSEARNIASAITPVPGGVGPMTIAFLMVNTVIAACNQAGIENFVEKYLDL
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: CYB_STRTC
Sequence: MRLLKNNIILRLLNSYMVDSPQPANLTYLWNFGSLLGICLVLQILTGCFLAMHFTPHAEMAFNSVEHIMRDVQSGWIVRYTHANVASFFFIFVYAHIGRGLYYNSYKSPRVLLWSIGVIILVLMMAIGFLGYVIPFGQMSLWGATVITNLLSAIPVFGQDIVELIWGGFSVSNATLNRFFSLHYILPFVLAALVVAHFMALHIHGSNNPNGVTSNTDRYPMYPYFIFKDLVTIFAFFWILSVIVFFYPNLMGHQDNYIPADPMVTPASIVPEWYLLPFYAILRSIPDKLLGVVAMFGSLLILLVLPLTDLSRIRGNQFRPAMKFFFWFFVVNFIMLFWLGSQHPNTPYLEIGQLSTTFYFSFFLVIVPFTGLVENTLLDLNIKELDLNL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RRF_SALTO
Sequence: MIDETLLEAEEKMERAIEHAKEEFGAIRTGRANAAMFSKIVIDYYGSPTPLPQMASIGVPEPRMVIIKPYDTSQTNAMEKAIRDSDLGVNPNNEGNQLRILLPQMTEERRREMIKVARHKGEEAKVAVRNVRRKAKEELDRLVKAGEVGEDDGRRAEKELDDLTQRFVGTVDELIKHKEAELLEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S39AE_XENTR
Sequence: MPLLLLSALLPFSLMAGPTPSTGKELSAASFLQDILQRYGENESLSMPQLQSLLENLEVGKGGGNQRNMSQCLSSSTLFAAHNLTSGSVVDAEGFQSFCPTILQQLETRACQESPAFQNETTPGAEGRPSPGEVWGYGFLCVTVISLCSLFGAGVVPFMKKACYKRLLLFCIALAIGTLFSNALFQLIPEAFGFNPLEDSYVFTSSVIFGGFYLFFFTEKVLKMMLKQKHEHGHSHYSADTSKRDAEEGVTEKLQNGDLDHMIPPPHGSESDLRGDEKAVQQQDLPGQQSSCYWLKGIRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGVSTSIAILCEEFPHELGDFVILLNAGMSIPQALFFNFLSACCCYLGLAFGILAGSHFSSNWIFALAGGMFLYIALSDMFPEMNEVSKEDEEGGRAFSAFMIQNAGLLTGFAIMLLLTTFSGQIQLG
What is the function of this protein?
Electroneutral transporter of the plasma membrane mediating the cellular uptake of the divalent metal cations zinc, manganese and iron that are important for tissue homeostasis, metabolism, development and immunity (By similarity).  Functions as an energy-dependent symporter, transporting through the membranes an electroneutral complex composed of a divalent metal cation and two bicarbonate anions.  Beside these endogenous cellular substrates, can also import cadmium a non-essential metal which is cytotoxic and carcinogenic (By similarity).
What are the official names of this protein?
Metal cation symporter ZIP14, Solute carrier family 39 member 14, Zrt- and Irt-like protein 14, ZIP-14.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi- pass membrane protein.
Protein: EX7L_CAMJJ
Sequence: MTPTELNLKAKALLETHFDDIVLSGEISKITLHGSGHWYFDLKDERSSIACAMFKGANLKVGFKPAVGNFLELCGSVSLYPESGRYQFIATSMKKAGFGDLEAQFLALKERLQKEGLFDPRFKKSLPKFPKKVGIITSKTSAALQDMLKLIHQKEYFLAKIYIFDALTQGNNAPFSLIQALKKADDMDLDVLIIARGGGSREDLFCFNDENLAREIFKAKTPIISAIGHEIDYVISDFVADFRAPTPSAAIDTLFYSKLDIEQSLDLMEEKLMQLWNYKIQNYENLLLNLSKFFKFNSLPKIIDEKIKQSHNIEKQLNHLLANQMRYNELKLDKLQNAYLQHENFFNKSKKFICIRKNGKIANLEDLKSDDIVILSSQTSQKEAKIL
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPC_SOLDE
Sequence: MASISSLNQIPCKTLQITSQYSKPTSKISTLPISSTNFLSKTEQHRSISVKEFTNPKPKFTAQATNYDKEDEWGPEVEQIRPGGVAVVEEEPPKEPSEIELLKKQLADSLYGTNRGLSASSETRAEIVELITQLESKNPNPAPTEALTLLNGKWILAYTSFSGLFPLLSRGNLPLVRVEEISQTIDSESFTVQNSVVFAGPLATTSISTNAKFEVRSPKRVQIKFEEGIIGTPQLTDSIVLPENVEFLGQKIDVSPFKGLITSVQDTASSVVKSISSQPPIKFPITNNNAQSWLLTTYLDDELRIPRGDAGSVFVLIKEGSPLLKP
What is the function of this protein?
Required for normal plant growth.  May be both photoprotective and play an ancillary role in photosynthesis.  May structurally stabilize thylakoids during osmotic and oxidative stress.
What are the official names of this protein?
Light-induced protein, chloroplastic, C40.4.
What is the protein family that this protein belongs to?
Belongs to the LIPC family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane.
Protein: GRP75_CHICK
Sequence: MISASRAAARLPLLLPRGGPVPAVPGLAQTFWNGLSQNVLRAASSRKYASEAIKGAVIGIDLGTTNSCVAVMEGKQAKVLENSEGARTTPSVVAFTADGERLVGMPAKRQAVTNPHNTFYATKRLIGRRFDDSEVKKDIKNVPFKIVRASNGDAWVEAHGKLYSPSQIGAFVLMKMKETAENYLGHPAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKSEDKIIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLQYIVKEFKRETSVDLTKDNMALQRVREASEKAKCELSSSVQTDINLPYLTMDASGPKHLNMKLSRSQFEGIVADLIKRTVAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLFGRAPSKAVNPDEAVAIGAAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMASDNKLLGQFTLVGIPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDEIENMVKNAEKYAEEDRRRKERVEAVNLAEGIIHDTESKMEEFKDQLPADECNKLKEEIAKMRELLARKDTETGENIRQAATSLQQASLKLFEMAYKKMASERESSGSSGDQKEEKQ
What is the function of this protein?
Chaperone protein which plays an important role in mitochondrial iron-sulfur cluster (ISC) biogenesis.  Interacts with and stabilizes ISC cluster assembly proteins FXN, NFU1, NFS1 and ISCU.  Regulates erythropoiesis via stabilization of ISC assembly.  May play a role in the control of cell proliferation and cellular aging.
What are the official names of this protein?
Stress-70 protein, mitochondrial, 75 kDa glucose-regulated protein, GRP-75, Heat shock 70 kDa protein 9.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TRMB_MARMM
Sequence: MTTEPTQNPAFRLFGRSQGKPLSARQQRLVDEFLPRIGLPDDGPIDPAALMPDRRRQALEIGFGGGEHLVAQAEANPQTGFIGIEPFLNGVAKALTAIDAAGLGNVRLARADAREILPRFETASLDQIFLLFPDPWHKKRHAKRRFVQQSTRDEFARLLKPGGRLRIATDVKSYADHCMVELSGDDRFIWQARTADDWTLPPADHITTRYETKNLGDCAPVFMDFLRV
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: NCCN_ALCXX
Sequence: MNISLRPAIAAPSPLDSFLTRHRIGIWRVVVSVVLIALITGHSQWDDTWISAALLTVGMLGVTMATVGRLWCALYISGRKSTELVTTGPYSMCRHPLYVCNFVGIVGLGAMTESITLAAILALAFALMYPAVIRSEDHLLSRNFPEFDDYARRTPAFFPRLSLFRSESTYLVHVGSFQRNLADSVWFLGMTIVVNAVELARHAKWLPTFVLLP
What is the function of this protein?
Component of the NCC cation-efflux system that confers resistance to nickel, cobalt and cadmium.  Appears to be involved in metal specificity but affects only nickel resistance.  May be involved in nickel transport.
What are the official names of this protein?
Nickel-cobalt-cadmium resistance protein NccN.
What is the protein family that this protein belongs to?
To A.eutrophus CzcN.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y224_CALS8
Sequence: MPRPIRCRRVEFLPKFKYFSPAQGTSDEVTLKIEELEAIRLKDLEGLMQEECAQKMQVSRQTFQLILEEARKKIADALVHGKAIRIEGGNYVYGKCSYICLNCGKVFDSDYHECPECHSKDIGCTRGRGRCYCFGHGRR
What are the official names of this protein?
UPF0251 protein Csac_0224.
What is the protein family that this protein belongs to?
Belongs to the UPF0251 family.
Protein: COAD_PAEAT
Sequence: MRRAVCPGSFDPIHNGHLEVIARAAGLFDEVIVAVSTNYAKKYRFSLEDRMEMARETLASLRGIIVEPMGEGLLAEYCRHRGVSAIVKGLRSSSDFDYELPMATMNRQLTGVETVFLPAEAHYVHLSSTLIKEVNVLGGDISEYVPKSVLKRLLAGEPPTEPSRKG
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM_HAEI8
Sequence: MLMQSIYLSKIREQNPLIHNITNIVAANFSANGLLALGASPLMSANIEEMQEVPKISQVLVINIGTLIGKDREAMLQAGKTANEVGIPVVLDPVGVGATSYRRETIRQLLAEVKFALIRGNAGELAAIAGETWQAKGVDAGQGEVDLKAVAEKVAQRYGCTVLISGAVDIVSDGTQTATVHNGTSLFPKVTASGCLLSAVCAAFLAVSEGNYFSATLEACVAYTIAGECAAQGLTTQVGQFQIRLLDELAALSPETIGQRGRINE
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.