PharMolix/UniProtQA huggingface dataset:
Protein: MYLK2_BOVIN
Sequence: MATENGAVELEIPSSSTDTAPKAAAGEGPPAAEKDPGPPDPQKDPGPPDPEKDAGPPNPEKELESPDPKKEPDPDSTKDTEAPAPEKGDGASAQPSASSQGPEGEGGLQGEPAEGSAGQPAALPQETATAEASVKKPEAEQGTPGSQDPGEAKEQKKVAEGQAPSKKGSPAFLHSPSCPAAISSLEKPLAEKPLDETLELIFEGVPVTPGPTETEPAKVAEGEKNLPGGSQKEGEEKAAGHAGQDGVQGDTSRGIEFQAVPSERSEVGQALSPTAKEEDCFQILDDCPPPPAPFPHRIVELRPGNINSQFSLNSKEALGGGKFGAVCTCTEKATGLKLAAKVIKKQTPKDKEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFERIVDEDYQLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSLGVITYMLLSGLSPFLGDDDTETLNNVLSSNWYFDEETFEAVSDEAKDFVSNLIVKDQRARMSAAQCLAHPWLNNLAEKAKRCNRRLKSQILLKKYLMKRRWKKNFIAVSAANRFKKISSSGALMALGV
What is the function of this protein?
Implicated in the level of global muscle contraction and cardiac function.  Phosphorylates a specific serine in the N-terminus of a myosin light chain (By similarity).
What are the official names of this protein?
Myosin light chain kinase 2, skeletal/cardiac muscle, MLCK2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Colocalizes with phosphorylated myosin light chain (RLCP) at filaments of the myofibrils.
Protein: MGST1_RAT
Sequence: MADLKQLMDNEVLMAFTSYATIILAKMMFLSSATAFQRLTNKVFANPEDCAGFGKGENAKKFLRTDEKVERVRRAHLNDLENIVPFLGIGLLYSLSGPDLSTALIHFRIFVGARIYHTIAYLTPLPQPNRGLAFFVGYGVTLSMAYRLLRSRLYL
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
What are the official names of this protein?
Microsomal glutathione S-transferase 1, Microsomal GST-1, Microsomal GST-I.
What is the protein family that this protein belongs to?
Belongs to the MAPEG family.
What are the subcellular locations of this protein?
Microsome. Mitochondrion outer membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SPC25_DROVI
Sequence: MSNQFNTRKRLMAMLANEMRLEQEENAIAKQSAKFHSKFATTMENIKRQQHESKKLNTLLNQRRDEVEKRNALKNAVRDKLAEEEQHCAEMQAQLGKKKQERDKLIACAHILSEAANTYINRKALPERVKGVAVSPDNGQWIPFDFNAHDRQGLAALWTQVNRSSRNINKWRQLSSVGNSSMPAPSGKENANVSMTSVIEIDLTSPPSQK
What is the function of this protein?
Acts as a component of the essential kinetochore-associated Ndc80 complex, which is required for chromosome segregation and spindle checkpoint activity during meiosis and mitosis.  Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.  Participates in SAC signaling that responds specifically to disruptions in spindle microtubule dynamics.  The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.
What are the official names of this protein?
Kinetochore protein Spc25.
What is the protein family that this protein belongs to?
Belongs to the SPC25 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore.
Protein: Y6251_DICDI
Sequence: MKLKINIRPNEIIFLICIVVIFSFSYTLTYFDSPIFKEHYITNNGNDFGVENHFVTYHSTYKEDIHKRIIDPHHGLIQEITKTFYPVSSPLEKLFSFSDNILIVLIIVQVIVGFLIFLLSVEKLSKCNYQLKSIFSTKSTFYINNNNNNNNEDINNNNNNNNNNNNKNKNDERNNEEIEDEETIRKEKILIIKKKRDILLAIIIFFLVLLGVLTIIYVSFIPLNIRKAFIGQQFYYKGSIDPLCADISNEGDHHIGKCKSLNGRIGNVNDKIFGYSWSLDSGLFNVKIVFFSTILIEFLTGCLILLMKFKKDPNIVPLTKPSIASPTQIPHLFCIAK
What are the official names of this protein?
Uncharacterized transmembrane protein DDB_G0284909.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SMUG1_HUMAN
Sequence: MPQAFLLGSIHEPAGALMEPQPCPGSLAESFLEEELRLNAELSQLQFSEPVGIIYNPVEYAWEPHRNYVTRYCQGPKEVLFLGMNPGPFGMAQTGVPFGEVSMVRDWLGIVGPVLTPPQEHPKRPVLGLECPQSEVSGARFWGFFRNLCGQPEVFFHHCFVHNLCPLLFLAPSGRNLTPAELPAKQREQLLGICDAALCRQVQLLGVRLVVGVGRLAEQRARRALAGLMPEVQVEGLLHPSPRNPQANKGWEAVAKERLNELGLLPLLLK
What is the function of this protein?
Recognizes base lesions in the genome and initiates base excision DNA repair.  Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates.  The activity is greater toward mismatches (U/G) compared to matches (U/A).  Excises uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA, but not analogous cytosine derivatives (5-hydroxycytosine and 5-formylcytosine), nor other oxidized bases.  The activity is damage-specific and salt-dependent.  The substrate preference is the following: ssDNA > dsDNA (G pair) = dsDNA (A pair) at low salt concentration, and dsDNA (G pair) > dsDNA (A pair) > ssDNA at high salt concentration.
What are the official names of this protein?
Single-strand selective monofunctional uracil DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. SMUG1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TX139_LYCSI
Sequence: MLKVLVVVALLVTLISYSSSEGIDDLEADELLSLMANEQTRKECIPKHHECTSNKHGCCRGNFFKYKCQCTTVVTQDGGQTERCFCGTPPHHKAAELVVGFGKKIFG
What are the official names of this protein?
U1-lycotoxin-Ls1w, Toxin-like structure LSTX-A39.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 04 (U1-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS15_MESFC
Sequence: MITKAKKAEIITRFGKSEKNTGDISVQIALLPEDIEKLKLHFEKNKKDKHSMRGFIAKVNKRKKLLNYLKEKNFASYKETIEALNIRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: Y802_TREPA
Sequence: MQHAPTQSQDTPCTRQGCSPFIYARRAGTPLRAARTAKTMQPRETSSCKRKTQYNLGSVTSGAHTITPAHAKLPLAQRYCKFTRVTREQHYPENNWENGLICRTPADTL
What are the official names of this protein?
Uncharacterized protein TP_0802.
Protein: HYLS1_XENLA
Sequence: MSLRDRQFREEPSENALPLDRNHFRPSTEYDQSYEPLEASGQSGDSDLVSEYAQGNMSVTVSEEELRHELSLLGFSYVPRQRLLEFKKDLERLMNRGSAAASPETSRLENESLDDSTNTPPPLPIETSAWHQTSAWPTTTSTSSKEWDNQQRNQDSYTKHTVSLGGNVQATKKAPQITRKVLRRKSDGQTHVSDESFLYSETETEEEDTGSSIVDFRSESSGRSSASCAKSFIRPPLYSLLDQYRQRSDPVGRYQEYKQKWDALQGALERNRKELRWGIREQMMSAPPQPAARSVLLPNTYVIPTDKKRYALRWAVRRDLVNGVMPRGSYS
What is the function of this protein?
Plays an important role in ciliogenesis.  Required for apical targeting/anchoring of centrioles at the plasma membrane.
What are the official names of this protein?
Centriolar and ciliogenesis-associated protein HYLS1, Hydrolethalus syndrome protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the HYLS1 family.
What are the subcellular locations of this protein?
Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localized to basal bodies in multiciliated cells (PubMed:19656802).
Protein: SEC16_DEBHA
Sequence: MSASFTDDKILRKSSVVEGGEISEELKILEKEPEHEPSEVVIGNDDDVKDDVKDDVKDDVKDDVKDDVKDDLKDDVEDDTIAPNQFEEAIKKNKLDPQDQTAAGDSGRSQPDLSPRTTTGVVKPSSFETKDTDGHDSAEVVSGSATQDDDNRNMDHDPITLVGDKRKSELQEYIPQTEADKEETKDFDPAQEDLTSADKAGKDQTPKVSDASEAKIDSLPWGPETSTDAKLPWETEDTNSDNKTADPIPWEQGSSDEASKNDDNLPWESNKNDAPSSQADNDKLPWESDINDAPSSQAGDDNLPWDSNTNDAPSSQAGDGNLPWDSNTNDAPSSQAEDDKLPWESDINNDVPASQEDPENKESNDSTNVDDLFGGSHNIDFLKEIQKQEESKDTDEVLLDSSENTPSAQPSSQDQDTSQDMRNYSTTQTDISHSEENKLALQSKNVPKGENEKTTENSDIHRPQDTDHFDDLFQNDDHDFLQEVGSSDNKSDPFKFPPDNSAPENKDSDKFETQNKSLDFLEMDDDLLDDEFLEDDTTSQTQTLKSKSNKQTYLPSTTNPSTTPVVPTQEKPKGSAMNKKKNDAYDFPDSLIAHKFKPAARSTNKYAPGSSNHNSPPVASMPPKLHSPSMNAVGSVPVPNEKQATMSQPLSAAVSTQGLQKKSFFEDLPIPVQKQPVKPARAALPRSQMSQSISPTVNPAQPQLQKPVVNPYAKPAMNTVVSPPMNYAQPPGMPQVTNNRGGSHLPAGMVAPPPPSQITGNNNVLPHAQPQPFPNMQNQNLGQNTNSYAPSRKISNPSPNLINTALPKVQGAQSATSPYVPNAGPYAPSSHKRTSSRASSLIGAKSKEVNPYAPASINVPNAQQGISHGIMMPNTASPTAPPAVMNNSIHGRRRGVSNVKSNFYHKEQTAPKVENPNALLQRQFPIFNWSSSKNIAYLIPSAVTNTYNRTSESVNVTDIKYVLKDSHYLSTFPGPFNKLKTKKKDVEKWLESYNEFLIQNNTGMKQDEVLVSQILLALVRFNGDCKSDDFTKAACAVLNPSVDYANDNTHMDMNPISTLANAYRLDNTGINIIWSLLQIGNTEKALEFCLSKGDWALGLMIARFEGPEKFGKVASDYARTTFPFQKSQSKVHHLMPIMLKLFAGNFKSAIDDITNVQAEGEWFIQNWRELVSLVVINKPQHGHEFLCEFSKLLALSGQIIASQICLILAGLPLSSIPSQANGILFSVIGFGSHSFAYSETYEYAMQLSTTNIPPTGFAHLLPLKLKHAQVLADYGLFTESQKYCDAISSIIKATGRSSFFNPVAFQEFQNLLMRISQSGASDSGWFGSKKLTLDKMWDQLDKFIGGDESKAKSGENGTFSKFSPAVSRAPSSLDITSLNNHYPQTSPQVRPDHIRDPLVTTNSAPGTSSENSVLKSNGMSHSRPPPSLYSNNSTTSIQKYAPSSSQVTPKPTLTRNDQSFSSQQQVGNPVYESLQQSRMAPNNSSSQYLPMNQGQSENIKAPSKYSANPQKVYSNNNGSLPYMNPSAQFSSSSIASHQSLHMGISGVNANPLTSVKRPSISNSFSESHVNSNPISGHKHTSSLQSDISLDYPSEFKSMPKPASDNPIAPDTHSSLKRDTENVPETITESRESEKSSELRDSSNSLTMPSEEGHSTVEDSTLPQAPPPKGHSKPNIASSSVAPKKARARANPYAPGAVASRSGGNNKYGPQSSDKYTSKKENTSMLVDTPSDISYNDIFNYGGYKVPKKTEINDTETLHDRNEVKEAPNQESIDTKEEASKTNSYIYPEPPKVASTSQSRNINVDESFDGENINDHDFETSSLHTPNANVPASNLNNSFRTNEKESMFHPYQEGENKSRRTSNFGVDSSFGDFPIPGSPDLTTRANSVIGGPGGLFSSRLSQSQQSALYQQYEVQDDTVKEYIPVVDEEEDEDSEDESSKKEKRKKEEQERQARIEADRAKQRQDAVASQRNQTWWPGFLARKNDDKPKAIRAKLGEKNKFVYDEKLKRWIDKSIPLEEQLKSSAPPPPPAAKKKPTEGSSSSISKPSSSSTPLGPAKQDMAPPASNSSNSAPSLGPSQSRPSQSGPPPPAGPSLANAGLDDLLSLGGGPSSGRKTKKGPRRGYVNLLDQK
What is the function of this protein?
Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules.  Also involved in autophagy (By similarity).
What are the official names of this protein?
COPII coat assembly protein SEC16, Protein transport protein SEC16.
What is the protein family that this protein belongs to?
Belongs to the SEC16 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RIMP_LEUCK
Sequence: MANKVAQEISTLIEPLINAQQLLLWDVSYTKEGGQKVLRILIDKRNHEFITMDDITTFTQAVNELLDTIEPDPIPEAYMLDISSPGADRPLIRPWHYEWAKASGENILVAFFVAKNGQKKWQGKIETIDDKGITLTTSSETIVCTFDEIAKAVLDTQF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_METST
Sequence: MSKRSNRSNNKNNTNKFNIENWEPKTELGRKVKDGEITDIDQILDKGLPIMELEIVDALLPDLEEEVMDVNLVQRMHKSGRKVNFRVIVAVGNRNGYVGLGQGKSQEVGPAIRKAVDAAKYNLIKVRRGCGDWGCGCGRRHTVPFKIEGKMSSVSATLIPAPAGVGLAIGNVGKTILSLAGIADVWSMCSGQTQTTINFAGAVFDALKQLSSVKSSEKDLKALGVID
What is the function of this protein?
With S4 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: LEUD_MYCBT
Sequence: MEAFHTHSGIGVPLRRSNVDTDQIIPAVFLKRVTRTGFEDGLFAGWRSDPAFVLNLSPFDRGSVLVAGPDFGTGSSREHAVWALMDYGFRVVISSRFGDIFRGNAGKAGLLAAEVAQDDVELLWKLIEQSPGLEITANLQDRIITAATVVLPFKIDDHSAWRLLEGLDDIALTLRKLDEIEAFEGACAYWKPRTLPAP
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: RL3_GEOSW
Sequence: MTKGILGRKIGMTQVFAENGDLIPVTVIEATPNVVLQKKTIEKDGYEAIQLGFEDISEKRANKPQIGHAAKANTAPKRFIREIRGANIDEYEVGQEVKVDIFAEGDIVDVTGISKGKGFQGAIKRHGQSRGPMAHGSRYHRRPGSMGAIAPNRVFKSKELPGRMGGQRVTIQNLKIVKVDPERNLLLIKGNVPGPRKGLVIVKSAVKAKAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RL21_IGNH4
Sequence: MVKAPKGWRHRTRHIYRKRVREKGAVPPLSLVLIDYKPGDKVIIDPNPAIWSGLPHRRFCGKVGEVVGKRGKAYLVKVRDGDVYKTIIVRPEHLRPFKQ
What are the official names of this protein?
50S ribosomal protein L21e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
Protein: HSP1_NEOBU
Sequence: MARYRRCRSRSRCRRRRRRCHRRRRRCCRRRRRRRACCRRYRCRRR
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity).
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PAT1_SCHPO
Sequence: MSFFGFNTTLPKENMFPNEGQLEEDGIDFEETYDDLGNQLNEAGDELNDETFGVSAGSIGRDFDFSGTTAQASAQLEDEQYQINQQNIFAKPVKPASSELPQVSRLNGASQFPSREPASTAINKLSDLQPMASIWENIVPEKPAIIPPEVASLQDRLGAQPSEKVFSLQELEEQLLNSMTAPKPPSQPAIPIVPSEMAAQVTRENISSLDPAISAASIGNVTFGQPNIPSTTTDFAGLAAPNMVHPSQAIPNPVMQPSLVPQMPYPQNGMYNPSVAPPASLVNLFQQEQLIQNQNLDEKRQKLERDHMLMAQCAGLMTRSDKSFIARIQISQLMSEDPESDDFYYRVYSIIRGRKPSEEEASHFIQTYLGPSNNRRRGRRSENPMQKLQQQLQRLVSSAKERPKATQLSLEGALGKIAVNTVRTPRQLLNVKRPTEPASSNSSLNNFSGFSTKKDVLHAIEKVYDLLLDFEQALRKASTLETTDQEQIDTWKTTLSEKLESIWKALYINESLEASSKTRPPFISIISHPKGMRLLPRLFPHLSKEQQISILKVVVYNFDSLDIVLRGTFDVNGELPLDVVSEMSSFTQFIIPPLLTIVNELDLETINNLFSQLLNRTNAVYLIQTKIGLSFLTLFISRAEILKQSGTVNQNEKEEWENTFNVMFNRVKGHFSTVFPPPNARAYADESYPWEFLAACATAASSEQHFTLVSETRDRVLDNIITSKRAPSEIAVVRISNVNLFLNAMGLDARQLSA
What is the function of this protein?
Activator of decapping that functions as a general and active mechanism of translational repression and required for P-body formation.  Stabilizes the 3' terminus of mRNAs and modulates the rates of mRNA-decapping that occur following deadenylation.  Might be required for promoting the formation or the stabilization of the preinitiation translation complexes.  Necessary for accurate chromosome transmission during cell division (By similarity).
What are the official names of this protein?
DNA topoisomerase 2-associated protein pat1, Decapping activator and translational repressor pat1, Topoisomerase II-associated protein pat1.
What is the protein family that this protein belongs to?
Belongs to the PAT1 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, P-body.
Protein: CRT_THEAN
Sequence: MLKEGSSLDLSASSSSGTLRSDNSFGNSPLDRITSLLILIYKSIRACFKWIYSKSFGIICILFVILDVLTTVFFKRFIDHTKNYVMFTIQVIIFTFWIIVCCIAILCFLFNREYMKRHFNVRPLVFLGFLDMLSTGLSANGSAHTSGLMLVLLGQISVPLTMVSCKLILSKKYHHYQYISSAIILTFAVLKPILNRTDTTDNRFYNNMLYLLASVPDSIASALREKQYTSKFFHVVKYQFFGFLFHFFYNILYTLLFTLPFNSVKGYFDSLYKLCVNGYKCIFFGVNTITENCGPTLIPTCDNCLEAFKIYCLYILFSSAIRVAYVFIMLDGSVTFTLLLGTVKVPLTSIAFSLRFIAGDSTTSFNLLDVVCFLGIVAGLLLYALGSKKIQEETDLLESPLIDDAESEHELLSTGTEKLMRSEICHDLFT
What is the function of this protein?
May regulate endogenous transporter.
What are the official names of this protein?
Putative chloroquine resistance transporter, Probable transporter cg10.
What is the protein family that this protein belongs to?
Belongs to the CRT-like transporter family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Localizes to the parasite digestive vacuole, the site of chloroquine action.
Protein: PME13_ARATH
Sequence: MAFQDFDKIQERVNANRKRKFRKRIIVGTVSLLVVVAAIVGGAFAYVAYEKRNEQQQQQQQAKNHNKSGSGNNVVKDSDKKSPSPPTPSQKAPVSAAQSVKPGQGDKIIQTLCSSTLYMQICEKTLKNRTDKGFALDNPTTFLKSAIEAVNEDLDLVLEKVLSLKTENQDDKDAIEQCKLLVEDAKEETVASLNKINVTEVNSFEKVVPDLESWLSAVMSYQETCLDGFEEGNLKSEVKTSVNSSQVLTSNSLALIKTFTENLSPVMKVVERHLLDDIPSWVSNDDRRMLRAVDVKALKPNATVAKDGSGDFTTINDALRAMPEKYEGRYIIYVKQGIYDEYVTVDKKKANLTMVGDGSQKTIVTGNKSHAKKIRTFLTATFVAQGEGFMAQSMGFRNTAGPEGHQAVAIRVQSDRSIFLNCRFEGYQDTLYAYTHRQYYRSCVIVGTIDFIFGDAAAIFQNCNIFIRKGLPGQKNTVTAQGRVDKFQTTGFVVHNCKIAANEDLKPVKEEYKSYLGRPWKNYSRTIIMESKIENVIDPVGWLRWQETDFAIDTLYYAEYNNKGSSGDTTSRVKWPGFKVINKEEALNYTVGPFLQGDWISASGSPVKLGLYDA
What is the function of this protein?
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
What are the official names of this protein?
Probable pectinesterase/pectinesterase inhibitor 13.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the pectinesterase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y2455_STAAB
Sequence: METLELQGAKLRYHQVGQRPVLIFIPGANGTGDIFLPLAEQLKDHFTVVAVDRRDYGESELTEPLPDSASNPDSDYRVKRDAQDIAELAKSLSDEPVYILGSSSGSIVAMHVLKDYPEVVKKIAFHEPPINTFLPDSTYWKDKNDDIVHQILTEGLEKGMKTFGETLNIAPIDAKMMSQPADTEKGRIEQYKRTMFWSEFEIRQYTHSDITLDDFTKYSDKITLLNGTDSRDSFPQDVNFYINKETGIPIVDIPGGHLGYIQKPEGFADVLLNMWG
What are the official names of this protein?
Uncharacterized hydrolase SAB2455.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: URE2_ACIBY
Sequence: MIPGEVITPETDIELNVGRETLKVVVANLGDRPIQVGSHFHFYEANDALQFDREAVKGFRLNIAAGTAIRFEPGQSREVEIVALAGKREVYGFAGRVMGKLD
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1786_FRAP2
Sequence: MILTTADTLGKREIIEYKGLVTGIIVRTPTITQGILGGLKNIIGGKNTSYTNVCKEARLHAEQEMINQAQELGANAIVAIRYDSSSLGGTTSGTEVFCYGTAVVIR
What are the official names of this protein?
UPF0145 protein Fphi_1781.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: FEOC_ECO24
Sequence: MASLIQVRDLLALRGRMKAAQISQTLNTPQPMINAMLQQLESMGKAVRIQEEPDGCLSGSCKSCPEGKACLREWWALR
What is the function of this protein?
May function as a transcriptional regulator that controls feoABC expression.
What are the official names of this protein?
Probable [Fe-S]-dependent transcriptional repressor.
What is the protein family that this protein belongs to?
Belongs to the FeoC family.
Protein: XGPT_ACTP2
Sequence: MSEKYTNEKYVVTWDMFHMHARKLAERLLPASQWKGIIAVSRGGLFPAAVLARELSIRHVETVCISSYDHDEQGELKVLHAAQTDGEGFIVVDDLVDTGNTAKEIRKMYPKAKFVTVFAKPAGTPLVDDYVIDIPQETWIEQPWDLGITFVPPLARK
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: M2_I80AC
Sequence: MSLLTEVETHTRSGWECRCNDSSDPLVIAASIIGILHLILWILDRLFFKCIYRRLKYGLKRGPSTEGVPESMREEYQQEKQSAVDVDDGHFVNIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: ISPE_CHLP8
Sequence: MKHFSVKACAKINLGLLITSRRDDGYHTLETIFAPIEWHDTLEFTESDKIGMECTNLDLPVDDTNLCIRAAKALQDYAGISKGVSMKLVKRVPFGAGLGGGSSDAAATLNALCRLWEIDVPSAVLHRLAVKLGADVPYFLEMKGLAYASGIGEELEDLSLALPWHVVTVFPEVQVPTAWAYKNFHRQFERPVPDLKALVRRLCDDRDLSVLDAFENDFGSVVFENYPVVSQVRDTLEASGAQFVSLSGSGSAVYALFENRALADETAEEMAGKFRVNVTPAGFRME
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: ARGB_BRUA2
Sequence: MTTLENPEMQAQLLSAALPYMQRYENKHVVVKYGGHAMGNPELGKAFARDVALLKQSGVNPIVVHGGGPQIQAMLTKLGIESRFEGGLRVTDEKTVEVVEMVLAGSINKEIVALINAEGEWAIGLCGKDGNMVFAQKAHKTVIDPDSNIEKVLDLGFVGEPAEVDRTLLDLLARSEMIPVIAPVAPGRDGHTYNINADTFAGAIAGALAATRLLFLTNVPGVLDKDKKLIKELSVADAQALIRDGTISGGMIPKVETCIDAIRRGVEGVVILNGKTPHSVLLELFTEHGAGTLIVP
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_SHEPA
Sequence: MNILLANPRGFCAGVDRAISIVERALELFSPPIYVRHEVVHNRYVVQNLKERGAVFVEELDQVPDDSIVIFSAHGVSQAVRAEAKRRGLKVFDATCPLVTKVHLQVARASRKGIECILIGHAGHPEVEGTMGQYDNSAGGVHLVESPEDVAKLVVKDPDNLCFVTQTTLSMDDTADVISSLQKKYPSIEGPRKDDICYATQNRQDAVRNVAEEVELFIVVGSKNSSNSNRLRELAQKKGTQAFLVDNADDVDATWFNGVERVAVTAGASAPEVLVKQVVDAIAKMAPSVVTEVEGQLEDTVFAVPAELR
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: I2BLB_XENLA
Sequence: MSAAQVSSSRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRIEFVIDTARQLKRSHSFQDGRSPGPQGPGSGASNKQHPAVQAALTAKDTAQLNHLDGATKASAASGLERYGLATERGRFEYSLAARLPNGLNGFPKPGEDGPPELNRQSPNSRGRSGHGLIPQLVPGQLSVPPNLLPQTLLNGPPSGNPTGAPHVLGRGPANSSGLGVPPTASSSGDPKRPGSVSSTDQERELKEKQRNSEALSELTESLRNRTEEWVGKPKAVRDALLTLTASAPFDVRFKKDHNLLGRVFAFDAASKPGLLDYELKLFVEYPSGSLNIFSSASGVAKQMYQDCMKDFGRGLSSGFKYLEYEKKHGSGDWRLLGDLLPESVRFFKEMVGADMLPQPYLDPGCPMLPSALVNLPRALAAAAASSSAGSSGQTRSGVRKRKASPEPDSADGQMWITGQSDGIKQLSMAPAGVTPSSSSSAAYGVPSAPPPPLGPGHPQRTTPPESAPPNGPSPMAALQSVTDTLGNAHSPKEGQTGGIPPVHSTTSSARRNSSSPVSPASVTGQRRLNSRNGAGSVELSLQVAPAGGAPHLGMDQVHPQNIPDSPMANSGPLCCTICHERLEDTHFVQCPSVPSHKFCFPCSRDSIKAQGATGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDP
What are the official names of this protein?
Interferon regulatory factor 2-binding protein-like B, Enhanced at puberty protein 1 homolog B.
What is the protein family that this protein belongs to?
Belongs to the IRF2BP family.
What are the subcellular locations of this protein?
Nucleus.