PharMolix/UniProtQA huggingface dataset:
Protein: PYRF_PHYB8
Sequence: MMLNTYKSYTERAEQHPNACARSLFELMERKKTNLSVAVDVTTKKELLSIADSVGPYVCVLKTHIDIVEDFDKDLVAQLEALAKKHDFLIFEDRKFADIGNTVKHQYEKGVYKIASWSHITNAHTVPGEGIIKGLGEVGLPLGRGLLLLAEMSSKGALTKGSYTTESVEMARRNKDFVFGFIAQHKMNEYPDEDFVVMTPGVGLDIKGDGLGQQYRTPHEVIVESGCDVIIVGRGIYGKPDEVEAQSKRYREAGWNAYLERVRMHKA
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase, Uridine 5'-monophosphate synthase, UMP synthase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family.
Protein: PSBC_ZYGCR
Sequence: MKTLYSLRRSYPVETLFNGTLALGGRDQATTGFAWWSGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVVDTFPYFVSGVLHLISSAVLGFGGVYHALIGPETLEESFPFFGYVWKDKNKMTTILGIHLILLGAGAFLLVFKALYFGGLYDTWAPGGGDVRKITNITLNPGVIFGYLLKSPFGGEGWIVSVDNLEDIVGGHVWLGSICILGGIWHILTKPFAWARRAFVWSGEAYLSYSLAAISVMGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEIIFGGETMRFWDLRAPWLEPLRGPNGLDLGKLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLSTSHFVLGFFFFVGHLWHAGRARAAAAGFEKGIDRDTEPVLFMNPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CALC_MOUSE
Sequence: MGFLKFSPFLVVSILLLYQACSLQAVPLRSILESSPGMATLSEEEVRLLAALVQDYMQMKARELEQEEEQEAEGSSLDSPRSKRCGNLSTCMLGTYTQDLNKFHTFPQTSIGVEAPGKKRDVAKDLETNHQSHFGN
What is the function of this protein?
Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
What are the official names of this protein?
Calcitonin.
What is the protein family that this protein belongs to?
Belongs to the calcitonin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RBSA1_RHIME
Sequence: MKPAIALEGISKSFPGVRALSDVSLALYPGSVTALVGENGAGKSTLVKILTGIYQPDAGTIRLGDTETTFPTALAASRAGVTAIHQETVLFDELSVAENIFLGHAPRNRFGLIDWKQLNADAQALLGRAGADFDPTIRLRDLGIAKKHLVAIARALSVDARVVIMDEPTAALSHKEIHELYDLIERLKADGKAVLFISHKFDEIFRIADRYTVFRDGAMIGEGLIADVSQDDLVRMMVGRAVGSVYPKKEVTIGQPVLTVSGYRHPTEFEDINFELRRGEILGFYGLVGAGRSEFMQSLIGITRPSAGAVKLDGEVLVIRSPAEAIRAGIVYVPEERGRQGAIIGMPIFQNVTLPSLSHTSRSGFLRLAEEFALAREYTSRLDLRAAALDQDVGTLSGGNQQKVVIAKWLATRPKVIILDEPTKGIDIGSKAAVHAFMSELAAQGLSVIMVSSEIPEIMGMSDRVIVMREGRVAGRYERSELTAEKLVRAAAGIETQADGRAA
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PSAC_ATRBE
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLWHETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: CRP_SHIFL
Sequence: MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTHPDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR
What is the function of this protein?
A global transcription regulator.  Complexes with cyclic AMP (cAMP) which allosterically activates DNA binding to regulate transcription.  It can act as an activator, repressor, coactivator or corepressor.  Induces a severe bend in DNA.  Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP.  Plays a major role in carbon catabolite repression (CCR) (By similarity).
What are the official names of this protein?
cAMP-activated global transcriptional regulator CRP, Catabolite activator protein, CAP, Catabolite gene activator, cAMP receptor protein, CRP, cAMP regulatory protein.
Protein: TOLB_SHIDS
Sequence: MKQALRVAFGFLILWASVLHAEVRIVIDSGVDSGRPIGVVPFQWAGPGAAPEDIGGIVAADLRNSGKFNPLDRARLPQQPGSAQEVQPAAWSALGIDAVVVGQVTPNPDGSYNVAYQLVDTGGAPGTVLAQNSYKVNKQWLRYASHTASDEVFEKLTGIKGAFRTRIAYVVQTNGGQFPYELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLAYVTFESGRSALVIQTLANGAVRQVASFPRHNGAPAFSPDGSKLAFALSKTGSLNLYVMDLASGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYKVNINGGAPQRITWEGSQNQDADVSSDGKFMVMVSSNGGQQHIAKQDLATGGVQVLSSTFLDETPSLAPNGTMVIYSSSQGMGSVLNLVSTDGRFKARLPATDGQVKFPAWSPYL
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.  TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DEF_RHOPT
Sequence: MALREIIILPDKRLREISKPVTEVTTEIRKLADDMFESMYEAPGIGLAAIQIAEPVRLITMDIVRKEGDGKSDPRAFINPEIVGASSEMNVYEEGCLSIPEYYAEVERPKTVRIRYTDLDGNVKEEDADGLFATCIQHEIDHLNGVLFVDHLSKLKRAMVIRKFEKAAKRGIKYV
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: NDB1_ARATH
Sequence: MTLLSSLGRASRSAPLASKLLLLGTLSGGSIVAYADANEEANKKEEHKKKKVVVLGTGWAGISFLKDLDITSYDVQVVSPQNYFAFTPLLPSVTCGTVEARSIVESVRNITKKKNGEIELWEADCFKIDHVNQKVHCRPVFKDDPEASQEFSLGYDYLIVAVGAQVNTFGTPGVLENCHFLKEVEDAQRIRRGVIDCFEKAILPGLTEEQRRRKLHFVIVGGGPTGVEFAAELHDFIIEDITKIYPSVKELVKITLIQSGDHILNTFDERISSFAEQKFTRDGIDVQTGMRVMSVTDKDITVKVKSSGELVSIPHGLILWSTGVGTRPVISDFMEQVGQGGRRAVATNEWLQVTGCENVYAVGDCASIAQRKILGDIANIFKAADADNSGTLTMEELEGVVDDIIVRYPQVELYLKSKHMRHINDLLADSEGNARKEVDIEAFKLALSEADSQMKTLPATAQVAAQQGAYLAKCFNRMEQCKELPEGPKRFRTGGHHQFRPFQYKHFGQFAPLGGDQAAAELPGDWVSAGKSAQWLWYSVYASKQVSWRTRALVVSDWTRRYIFGRDSSRI
What is the function of this protein?
Alternative NADH-ubiquinone oxidoreductase which catalyzes the oxidation of mitochondrial NADH does not translocate protons across the inner mitochondrial membrane (By similarity).  Calcium-dependent NAD(P)H dehydrogenase.  Binds calcium ions.
What are the official names of this protein?
External alternative NAD(P)H-ubiquinone oxidoreductase B1, mitochondrial, External alternative NADH dehydrogenase NDB1, NADH:ubiquinone reductase (non-electrogenic) NDB1.
What is the protein family that this protein belongs to?
Belongs to the NADH dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Peroxisome.
Protein: Y481_PROMP
Sequence: MAENFSFDVVSDFDRQELVNALDQVKREISQRYDLKGTDTSLDLEKDNIFITTNSELTLNSVIDIIRQKAIKRKLSIKIFDFNSIEVVSGNKVKQTITLKKGLNQEIAKKISKNIRDEIKKINVSINGETLRVMSKSKNDLQLAIKLLENLEETYKIPLQTNNYR
What are the official names of this protein?
UPF0234 protein PMM0481.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: YJU2_MOUSE
Sequence: MSERKVLNKYYPPDFDPSKIPKLKLPKDRQYVVRLMAPFNMRCKTCGEYIYKGKKFNARKETVQNEAYLGLPIFRFYIKCTRCLAEITFKTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLRQHRMSQEQWQQQQEEEDERETAALLEEARHRRLLEDSESEDEAPPSRPRAAARPNPTAILNEVPQTKRKAEALCSKAQLAGLVVPKKVKTEANGASEQVGVPTAAGAPKSRKADNPTPQTPGTSSLSQLGAYGDSEDSDS
What is the function of this protein?
Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA.  Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates.  May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex.
What are the official names of this protein?
Splicing factor YJU2, Coiled-coil domain-containing protein 94.
What is the protein family that this protein belongs to?
Belongs to the CWC16 family. YJU2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: YQGF_AYWBP
Sequence: MLNCQNNASLGLDLGEKTLGIALSQTGIIAQNLKTIFFDTHKYDQLIAPLQKIISQYQIKKIILGYPKHMNNDIGIKAKISNYFKKTLENKFGQVKVILWDERLSTVQAIQILKTNNKKKGKILQMKDEIAASIILQNYLDYIKLHPNKEN
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_CUPPJ
Sequence: MNLRPLHDRVIVKRLDNETKTASGIVIPDNAAEKPDQGEVLAIGPGKKDDKGNNIALDVKVGDRVLFGKYAGQGVKVDGQELLVMREEDIMAVVNK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TNR6C_HUMAN
Sequence: MATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLAHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVDRPTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAAQARTMQQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNGSSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGKLSDIKSTWSSGPTSHTQASLSHELWKVPRNSTAPTRPPPGLTNPKPSSTWGASPLGWTSSYSSGSAWSTDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQALPPTSSWQSSSASSQPRLSAAGSSHGLVRSDAGHWNAPCLGGKGSSELLWGGVPQYSSSLWGPPSADDSRVIGSPTPLTTLLPGDLLSGESL
What is the function of this protein?
Plays a role in RNA-mediated gene silencing by micro-RNAs (miRNAs).  Required for miRNA-dependent translational repression of complementary mRNAs by argonaute family proteins.  As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes.
What are the official names of this protein?
Trinucleotide repeat-containing gene 6C protein.
What is the protein family that this protein belongs to?
Belongs to the GW182 family.
Protein: ETF1_VACCC
Sequence: MNTGIIDLFDNHVDSIPTILPHQLATLDYLVRTIIDENRSVLLFHIMGSGKTIIALLFALVASRFKKVYILVPNINILKIFNYNMGVAMNLFNDEFIAENIFIHSTTSFYSLNYNDNVINYNGLSRYNNSIFIVDEAHNIFGNNTGELMTVIKNKNKIPFLLLSGSPITNTPNTLGHIIDLMSEETIDFGEIISRGKKVIQTLLNERGVNVLKDLLKGRISYYEMPDKDLPTIRYHGRKFLDTRVVYCHMSKLQERDYMITRRQLCYHEMFDKNMYNVSTAVLGQLNLMNNLDTLFQEQDKELYPNLKINNGVLYGEELVTLNISSKFKYFINRIQTLNGKHFIYFSNSTYGGLVIKYIMLSNGYSEYNGSQGTNPHMINGKPKTFAIVTSKMKSSLEDLLDVYNSPENDDGSQLMFLFSSNIMSESYTLKEVRHIWFMTIPDTFSQYNQILGRSIRKFSYADISEPVNVYLLAAVYSDFNDEVTSLNDYTQDELINVLPFDIKKLLYLKFKTKETNRIYSILQEMSETYSLPPHPSIVKVLLGELVRQFFYNNSRIKYNDSKLLKMVTSVIKNKEDARNYIDDIVNGHFFVSNKVFDKSLLYKYENDIITVPFRLSYEPFVWGVNFRKEYNVVSSP
What is the function of this protein?
Acts with RNA polymerase to initiate transcription from early gene promoters.  Is recruited by the RPO-associated protein of 94 kDa RAP94/OPG109 to form the early transcription complex, which also contains the core RNA polymerase.  ETF heterodimer binds to early gene promoters.
What are the official names of this protein?
Early transcription factor 70 kDa subunit, ATP-dependent helicase VETFS, ETF small subunit, VETF D6 subunit, Vaccinia virus early transcription factor small subunit, VETF small subunit.
What is the protein family that this protein belongs to?
Belongs to the helicase family. VETF subfamily.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).
Protein: XYNA_ASPFC
Sequence: MVSFSYLLLACSAIGALAAPVEPETTSFNETALHEFAERAGTPSSTGWNNGYYYSFWTDGGGDVTYTNGAGGSYSVNWRNVGNFVGGKGWNPGSARTINYGGSFNPSGNGYLAVYGWTTNPLIEYYVVESYGTYNPGSGGTFRGTVNTDGGTYNIYTAVRYNAPSIEGTKTFTQYWSVRTSKRTGGTVTMANHFNAWSRLGMNLGTHNYQIVATEGYQSSGSASITVY
What is the function of this protein?
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Probable endo-1,4-beta-xylanase A, Xylanase A, 1,4-beta-D-xylan xylanohydrolase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 11 (cellulase G) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PUR9_SHIBS
Sequence: MQQRRPVRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLLAEKGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDAIMEEHQIQPIDMVVVNLYPFAQTVAREGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEMDDNEGSLTLATRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNLNFIKKQDMRYGENSHQQAAFYIEENVKEASVATATQVQGKALSYNNIADTDAALECVKEFAEPACVIVKHANPCGVAIGNSILDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAIISRQFVEVIIAPSASEEALKITAAKQNVRVLTCGQWGERVPGLDFKRVNGGLLVQDRDLGMVGAEELRVVTQRQPTEQELRDALFCWKVAKFVKSNAIVYAKNNMTIGIGAGQMSRVYSAKIAGIKAADEGLEVKGSSMASDAFFPFRDGIDAAAAAGVTCVIQPGGSIRDDEVIAAADEHGIAMLFTDMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: SET1_NEUCR
Sequence: MSRSSGASFAQFFPAAPRAARDRATERERARMRAQASPPTQPLDTNGHRTPLSSFTSNRSDDGASPGRSHITSLNHSSSAGADATRPPLEDTESLPGDTLNTVGSASSHTSTSSSIFSSSTRQPAMASASVRNSHTHNSTTPLTTAGSPSSLYLSTSLHAKPHSVSPHHADKQNGLTPTLNGSATDSLVPLPDGTERVPPRDPSRSVLCTICTYDPLLDKKLSSSEKKKAKPIYKDYGLNDEDDAPPSDPRLAHGGKLSYINVNFHLPKAQLIDAPSNLKPYPYDPKTSCGPGPPVQILVRGFNPLIAFTKVTTIFASFGDIAESSNKMHPETGSYLGFATIRYKDSKPTSSRPVPVPAHQAARRAVRGMHGRRIEANQVRVEFDPEGRKSKALMEAVLKKSRETSQTPNAAYKIPTGPKPRAGEVIPGPPPTAPKGPAAHRALGGSEAGWTSTKPRHPNIIETEPIVNHIKSEPYIFVAHEYVPVMPTTVAHMKKRLKQYGFDDIRADRTGYYIIFRDSHYGRDEASKCYNSANDTAFFTYSMVMDLHLFGTVGKSSRSSEDHRRHSYGSEKRPPPEHRQRDDQDRRRRDEEADIEEEKKQRAKNLDPVKEAAEVIRREMTEHLLKTIRTKITLPAVFDYLNPVNHAAKRRKLNIDDSHSGTIPSIVFDDSEGRSSPVGTPNSRADPIERRTARADVSTLRVRKLKSRGVNARKHGFNDPFARARPTQRVDLRSLHHRLNSDSDDDSDDGVDNRYSMIRDTEEPESRPRSRVSSEEDRNKEETGSWVAGEDDSMTEASFALNDTSALLKKRKLDLPAETAVKRQKKAEELFEATIARIETELPSQEQAVESVTPTGVEAPLNGLPDADVKAEPAEDKETEDSRLPTPIPDNTKPKKKAKAKKKSKKQIFEEREALKKQQQETFEREALRAAGIEDIEGTPDAEAKSQVGEPEPVPEPELETKGEALEAPETESKPDLDPELYPSEVVDALVLPKDFNLDIGTLKLVPFHGEDGPDAQRLQRKFGTAKLDCDAELWLWRRNRIRQLNSEDGSVDKPVGIGGYYVPNPTGCARTEGVKKILNSEKSKYLPHHIKVKKAREEREKNAKNGNTNSVAAAAEAARLAADSLVAKGNSRANRVNNRRYVAEINDQRKNFGQDSDVLRFNQLKKRKKPVKFARSAIHNWGLYAMENINKDDMIIEYVGEEVRQQIAELREARYLKSGIGSSYLFRIDDNTVIDATKKGGIARFINHSCMPNCTAKIIKVEGSKRIVIYALRDIAQNEELTYDYKFEREIGSTDRIPCLCGTAACKGFLN
What is the function of this protein?
Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.
What are the official names of this protein?
Histone-lysine N-methyltransferase, H3 lysine-4 specific, COMPASS component set-1, SET domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: LAMC2_HORSE
Sequence: MPALWLRCGLCLALLLPAARASSGSQVCDCNGKSRQCIFDQELHKQTGNGFRCLNCNDNTDGIHCERCKAGFYRQRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGDRCDRCLPGFHTLTDAGCAQDQRLLDSKCDCDPAGISGPCDSGRCVCKPAVTGERCDRCRPGYYHLDGGNPQGCTQCFCYGHSASCHSSGDYSVHKIISAFHQDVDGWKAVQRNGSPAKLQWSQRHRDIFSSARRSDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPLMPLSKTLPCGITKTYTFRLNEHPSSNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTGYIDNVTLISARPVSGAPAPWVEQCVCPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDIPECADCPIGFYNDPQDPRSCKPCPCRNGFSCSVMPETEEVVCNNCPQGVTGARCELCADGYFGDPFGERGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGVHCDQCKAGYYGDPLAPNPADKCRACNCNPVGSEPVECRSDGSCVCKPGFGGLSCEHAALTSCPACYNQVKVQMDQFMQQLQILEALISKAQGGAVPNAELEGRMQQAEQALRDILREAQISQDAVRSFNLRVAKARTQENSYRDRLDDLKMTVERVRALGSQYQNQVQDTRRLITQMRLSLEESEASLQNTNIPPSEHYVGPNGFKSLAQEATRLADSHVQSASNMEQLAKETQEYSKELMSLVREALQEGGGSGSLDGAVVQRLVGKLQKTKSLAQELSREATQTDMEADRSYQHSLHLLNSVSQIQGVNDQSLQVEAKRLRQKADSLSNRVTKHMDEFKHVQSNLGNWEEETRQLLQNGKNGRQTSDQLLSRANLAKSRAQEALSMGNATFYEVENILKNLREFDLQVGDKRAEAEEAMKRLSYISQKVAGASDKTKQAEAALGSAAADAQRAKNAAREALEISGKIEQEIGGLNLEANVTADGALAMEKGLATLKSEMREVEGELSRKEQEFDMDMDAVQMVIAEAQRVENRAKNAGVTIQDTLNTLDGILHLIDQPGSVDEERLILLEQKLFRAKTQINSQLRPLMSELEERAHRQKGHLRFLETSIDGILADVKNLENIRDNLPPGCYNTQALEQQ
What is the function of this protein?
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.  Ladsin exerts cell-scattering activity toward a wide variety of cells, including epithelial, endothelial, and fibroblastic cells.
What are the official names of this protein?
Laminin subunit gamma-2, Epiligrin subunit gamma, Kalinin subunit gamma, Laminin-5 subunit gamma, Nicein subunit gamma.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component.
Protein: RS12_PECAS
Sequence: MATINQLVRKPRSLKAAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCSGVKDRKQSRSKYGVKKPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: DCOR_YEAST
Sequence: MSSTQVGNALSSSTTTLVDLSNSTVTQKKQYYKDGETLHNLLLELKNNQDLELLPHEQAHPKIFQALKARIGRINNETCDPGEENSFFICDLGEVKRLFNNWVKELPRIKPFYAVKCNPDTKVLSLLAELGVNFDCASKVEIDRVLSMNISPDRIVYANPCKVASFIRYAASKNVMKSTFDNVEELHKIKKFHPESQLLLRIATDDSTAQCRLSTKYGCEMENVDVLLKAIKELGLNLAGVSFHVGSGASDFTSLYKAVRDARTVFDKAANEYGLPPLKILDVGGGFQFESFKESTAVLRLALEEFFPVGCGVDIIAEPGRYFVATAFTLASHVIAKRKLSENEAMIYTNDGVYGNMNCILFDHQEPHPRTLYHNLEFHYDDFESTTAVLDSINKTRSEYPYKVSIWGPTCDGLDCIAKEYYMKHDVIVGDWFYFPALGAYTSSAATQFNGFEQTADIVYIDSELD
What is the function of this protein?
Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine.  Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.
What are the official names of this protein?
Ornithine decarboxylase, ODC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHSE_DESHY
Sequence: MVRVRIPATSANLGPGFDCLGMALSLYNVVQIEAADSFQIALKGDYTAGIPGDETNLVWQSMCNLWEAIGFEIPTVSLELENNIPPTRGMGSSSAAIVGGLVAANEYAGGVLSKQQILQIANRIEGHPDNVAPALLGGVTLAVTAEASVIARTVHSQPQFMALAIVPDFYLSTEKSRNVLPASISRADAVYNLSRTALLVEALIHENHELLKEGMQDRLHQNQRAGLVPGLGETLQVALDSGAYGSALSGSGPTILALVSSHRAEQVSQAMVDSLAAHGLTAKAYLLSVDSEGAAVI
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CREG1_HUMAN
Sequence: MAGLSRGSARALLAALLASTLLALLVSPARGRGGRDHGDWDEASRLPPLPPREDAARVARFVTHVSDWGALATISTLEAVRGRPFADVLSLSDGPPGAGSGVPYFYLSPLQLSVSNLQENPYATLTMTLAQTNFCKKHGFDPQSPLCVHIMLSGTVTKVNETEMDIAKHSLFIRHPEMKTWPSSHNWFFAKLNITNIWVLDYFGGPKIVTPEEYYNVTVQ
What is the function of this protein?
May contribute to the transcriptional control of cell growth and differentiation.  Antagonizes transcriptional activation and cellular transformation by the adenovirus E1A protein.  The transcriptional control activity of cell growth requires interaction with IGF2R.
What are the official names of this protein?
Protein CREG1, Cellular repressor of E1A-stimulated genes 1.
What is the protein family that this protein belongs to?
Belongs to the CREG family.
What are the subcellular locations of this protein?
Secreted.