PharMolix/UniProtQA huggingface dataset:
Protein: ITAS_BPT7
Sequence: MSNVAETIRLSDTADQWNRRVHINVRNGKATMVYRWKDSKSSKNHTQRMTLTDEQALRLVNALTKAAVTAIHEAGRVNEAMAILDKIDN
What is the function of this protein?
Plays a role in the inhibition of the host toxin-antitoxin (TA) system.  These modules made by the host and composed of a toxic gene and a neutralizing gene play role in stress response and programmed cell death.  Gp4. 5 interacts with the host protease lon to neutralize the degradation of the antitoxin that would result in the activation of the toxin and the destruction of the bacteria.
What are the official names of this protein?
Inhibitor of toxin/antitoxin system, Gene product 4.5, Gp4.5.
Protein: RDRP_I73A6
Sequence: MDVNPTLLFLKVPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSEKGKWTTNTETGEPQLNPIDGPLPEDNEQSGYAQQDCVLEAMAFLEESHPGIFENSCLETMEVVQQTRVDRLTQGRQTYDWTLNRNQPAATALANTIEVFRSNGLTANESGRLIDFLKDVMESMDKEEMEITTHFQRKRRVRDNMTKKMVTQRTIGKKKQRVNKRSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTELSFTITGDNTKWNENQNPRMFLAMMTYITKNQPEWFRNILSIAPIMFSNKMARLGKGYMFESKRMKLRTQIPAEMLASIDLKYFNESTRKKIEKIRPLLRDGTASLSPGMMMGMFNMLSTVLGVSILNLGQKKYTKTTYWWDGLQSSDDFALIVNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSYINRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMINNDLGPATAQMALQLFIKDYRYTYRCHRGHTQIQTRRSFELKKLWEQTRSKAGLFVSDGGPNLYNIRNLHIPEVCLKWELMDEDYQGRLCNPLNPFVSHKEIESVNNAVVMPAHGPAKSMEYDAVATTHSWIPKRNRSILNTSQRGILEDGQMYQKCCNLFEKFFPSSSYRRPVGISSMVEAMVSRARIDARIDFEAGRIKKEEFSEIMKICSTIEELRRQK
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: APA3_ARATH
Sequence: MGTRFQSFLLVFLLSCLILISTASCERNGDGTIRIGLKKRKLDRSNRLASQLFLKNRGSHWSPKHYFRLNDENADMVPLKNYLDAQYYGDITIGTPPQKFTVIFDTGSSNLWIPSTKCYLSVACYFHSKYKASQSSSYRKNGKPASIRYGTGAISGYFSNDDVKVGDIVVKEQEFIEATSEPGITFLLAKFDGILGLGFKEISVGNSTPVWYNMVEKGLVKEPIFSFWLNRNPKDPEGGEIVFGGVDPKHFKGEHTFVPVTHKGYWQFDMGDLQIAGKPTGYCAKGCSAIADSGTSLLTGPSTVITMINHAIGAQGIVSRECKAVVDQYGKTMLNSLLAQEDPKKVCSQIGVCAYDGTQSVSMGIQSVVDDGTSGLLNQAMCSACEMAAVWMESELTQNQTQERILAYAAELCDHIPTQNQQSAVDCGRVSSMPIVTFSIGGRSFDLTPQDYIFKIGEGVESQCTSGFTAMDIAPPRGPLWILGDIFMGPYHTVFDYGKGRVGFAKAA
What is the function of this protein?
Involved in the processing and degradation of storage proteins.
What are the official names of this protein?
Aspartic proteinase A3.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LIS1_ASPNC
Sequence: MTKILTSSQAEELHKSIIAYLSSINASRSCEVLREELQVDSSFDDALCRKYEGLLEKKWTGIARLQKKILDLESKLAGLQTELDTISPTARSTGKDPINWLPTSSRHTFESHRDAVTCVAFHPVFTSLASGSEDCTIKIWDWELGELERTLKGHMRPVSDLDFGGQKGHTILASCSSDLQIKLWDPNKDYANVRTLSGHDHSVSAVRFLRQTDNILISASRDATIRIWDVSTGYCVKVIDSQGSWINDVSPSFDGKWLVTGGRDQAAMVWEVASAKSVASLIGHENFIECCVFAPPSSYKHLAAIAGLKTAPPASSSSEFIATGARDKTIKLWESRGRLIKTLVGHDNWVRGLLFHPGGKYLISVADDKTIRCWDLSQGGRLVKTINAHGHFVSCIRWGPVPVSDVPVETSESTKSSKSDSVKPGFQCVIATGSADSSVRIFT
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Required for nuclear migration during vegetative growth as well as development.  Required for retrograde early endosome (EE) transport from the hyphal tip.  Required for localization of dynein to the mitotic spindle poles.  Recruits additional proteins to the dynein complex at SPBs.
What are the official names of this protein?
Nuclear distribution protein nudF, Lissencephaly-1 homolog, LIS-1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the plus ends of microtubules at the hyphal tip and the mitotic spindle poles.
Protein: S2538_ASPOR
Sequence: MSNSAVYAVPQVKKTSATTTSKTTFHFAAGLCSGLSSAILLQPADLLKTRVQQSQNAALLPTIKSIISSPNGIRGLWRGTLPSALRTGFGSALYFTSLNALRQGLAHTGVPVALSSASANGKGVASSSALPKLSNSANLATGAAARVAAGFVMMPVTVLKVRYESSYYAYGSLYSAGRDILRTEGVRGLFAGFGATAARDAPYAGLYVLFYEQLKRRFASLADSGTGDQSLKSSSSSINFVSGALAAGLATAITNPFDAVKTRLQLMPNKYGNMMRAVKLMVHEDGVRSLLGGLGLRITRKALSSALAWTVYEELILRAEKHWATRD
What is the function of this protein?
Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix.  Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix.
What are the official names of this protein?
Mitochondrial glycine transporter, Solute carrier family 25 member 38 homolog.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MSRA_METHJ
Sequence: MGIAFFAGGCFWGIEAGFQKVPGVINTKVGYMGGHTIEPTYQEVCSDTTGHAETIALEYDDTAITYRKLLEIFFSLHNPTEVNRQGPDVGSQYRSVIFYTSPEQKEEAEMFIAEMNQSGRYHAAIATEVVPAETFWPAEEYHQSYFLKIGQRYGRSLF
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: HMMR_RAT
Sequence: MGGGVSYVGWLEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEEDLKEKDREILCLKQSLEEKVSFSKQIEDLTVKCQLLEAERDDLVSKDRERAESLSAEMQVLTEKLLLERQEYEKLQQNELQSQSLLQQEKELSAHLQQQLCSFQEEMTSERNVFKEQLKLALDELDAVQQKEEQSEKLVKQLEEETKSTAEQLRRLDDLLREKEIELEKRTAAHAQATVIAQEKYSDTAQTLRDVTAQLESYKSSTLKEIEDLKLENLTLQEKVAMAEKRVEDVQQQILTAESTNQEYAKVVQDLQNSSTLKEAEIKEITSSYLEKITDLQNQLRQQNEDFRKQLEEEGAKMTEKETAVTELTMEINKWRLLYEELYDKTKPFQQQLDAFEAEKQALLNEHGATQEQLSKIRDSYAQLLGHQNLKQKIKHVVKLKDENSQLKSEVSKLRSQLAKRKQNELRLQGELDKALGIRHFDPPKAFCHESKENVTLKTPLKEGNPNCC
What is the function of this protein?
Receptor for hyaluronic acid (HA) (By similarity).  Involved in cell motility (By similarity).  When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including the PTK2/FAK1 occurs.  May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity (By similarity).  May act as a regulator of adipogenisis (By similarity).
What are the official names of this protein?
Hyaluronan-mediated motility receptor, Intracellular hyaluronic acid-binding protein, Receptor for hyaluronan-mediated motility.
What are the subcellular locations of this protein?
Cell surface. Cytoplasm. Cytoplasm, cytoskeleton, spindle.
Protein: LAD_TALEM
Sequence: MAAGISLTKPNIGVYTNPNHDLWVADAKPTLEEVKSGSDLKPGQVTVEIRSTGICGSDVHFWHAGCIGPMIVTGDHILGHESAGVVIAVAPDVKTLKPGDRVAIEPNIICNKCEPCLTGRYNGCEAVEFLSTPPVDGLLRRYVNHPAIWCHKIGDMSFEDGALLEPLSVALAGMDRAGVRLGDPVLVAGAGPIGLVTLLCVRAAGATPIVITDIDEGRLRFAKELVPEVRTYRVQTGLSAEENAAGILDALNDGNGSAPDAIRPRVAMECTGVESSVASAIWSVKFGGKVFVIGVGKNEMKVPFMRLSTWEIDLQYQYRYCNTWPKAIRLVKNGVINLKKLVTHRFPLEDAVKAFETAANPKTGAIKVQIMSSEEDIKAASGVNGASN
What is the function of this protein?
Catalyzes the NAD-dependent oxidation of L-arabinitol to L-xylulose in the fungal L-arabinose catabolic pathway.  L-arabinose catabolism is important for using plant material as a carbon source.  NADP cannot act as a cosubstrate.
What are the official names of this protein?
L-arabinitol 4-dehydrogenase, LAD.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: RNC_BACSU
Sequence: MSKHSHYKDKKKFYKKVEQFKEFQERISVHFQNEKLLYQAFTHSSYVNEHRKKPYEDNERLEFLGDAVLELTISRFLFAKYPAMSEGDLTKLRAAIVCEPSLVSLAHELSFGDLVLLGKGEEMTGGRKRPALLADVFEAFIGALYLDQGLEPVESFLKVYVFPKINDGAFSHVMDFKSQLQEYVQRDGKGSLEYKISNEKGPAHNREFEAIVSLKGEPLGVGNGRSKKEAEQHAAQEALAKLQKHHTKQ
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of ribosomal RNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Also processes pre-scRNA (the precursor of the signal recognition particle RNA).  Probably also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (PubMed:22229825, PubMed:26940229, PubMed:11123676, PubMed:17576666, PubMed:18363798, PubMed:22412379).  Probably processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism (Probable).  Involved in degradation of type I toxin-antitoxin system duplex RNAs (PubMed:22229825, PubMed:26940229).
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EG1_ORYSI
Sequence: MTLPRQCAAACRTGGGGGGVVRCRAVAAAGGAVAVRDAVVAPVARRGAARKTAETVAGMWREVQGCGDWEGMLEPAPHPVLRGEVARYGELVGACYKAFDLDPASRRYLNCKYGRERMLEEVGMGGAGYEVTRYIYAAADVSVPTMEPSTSGRGRWIGYVAVSTDEMSRRLGRRDVLVSFRGTVTPAEWMANLMSSLEAARLDPCDPRPDVKVESGFLSLYTSADKTCRFGGAGSCREQLLREVSRLVAAYSGGGEDVSVTLAGHSMGSALALLSAYDLAELGLNRAAPVTVFSFGGPRVGNAAFKARCDELGVKALRVTNVHDPITKLPGVFLNEATAGVLRPWRHSCYTHVGVELPLDFFKVGDLASVHDLATYISLLRGADKKQPAAAAADAGGVLAKVMDFVGRRRGGGALPWHDAAMIQMGGLVQTLGLI
What is the function of this protein?
Phospholipase that releases free fatty acids from phospholipids.  Catalyzes the initial step of jasmonate (JA) biosynthesis.  Required for the biosynthesis of endogenous JA in seedling, inflorescence and spikelets.  Not essential for JA biosynthesis after wounding.  Mediates spikelet development and specification of empty-glume identity.  Functions in a high temperature-dependent manner to maintain floral developmental robustness under heat stress conditions.  Functions by safeguarding the expression of several floral identity genes, such as MADS1, MADS6 and G1.
What are the official names of this protein?
Phospholipase A1 EG1, chloroplastic/mitochondrial, Protein EXTRA GLUME 1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
Protein: HSPB7_RAT
Sequence: SSSSSSASRALPAQDPPMEKALSMFSEDFGSFMLPHSEPLTFPARPGGQGNIKTLGDAYEFTVDMRDFSPEDIIVTTSNNHIEVRAEKKP
What are the official names of this protein?
Heat shock protein beta-7, HspB7, Cardiovascular heat shock protein, cvHsp.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, Cajal body. Note=Resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Protein: HNS_SALTY
Sequence: MSEALKILNNIRTLRAQARECTLETLEEMLEKLEVVVNERREEESAAAAEVEERTRKLQQYREMLIADGIDPNELLNSMAAAKSGTKAKRAARPAKYSYVDENGETKTWTGQGRTPAVIKKAMEEQGKQLEDFLIKE
What is the function of this protein?
Binds tightly to dsDNA (PubMed:10844682).  Acts as a global transcriptional regulator through its ability to bind to AT-rich DNA sequences (PubMed:1423593, PubMed:16933988, PubMed:21673140).  Binds in the minor groove of AT-rich DNA (PubMed:21673140).  Was found to bind 746 genes, about half of which show no change in expression in disruption experiments suggesting these sites are important for nucleoid structure (PubMed:16933988).  On a global level genes bound by H-NS are expressed at a lower than average level; H-NS is excluded from binding to highly transcribed genes and does not co-localize with RNA polymerase in DNA-binding studies during exponential growth in rich medium (PubMed:16933988).  The best correlation for H-NS binding is AT-content rather than predicted DNA curvature (PubMed:16933988).  Has a strong preference for DNA that has been recently acquired by horizontal gene transfer, binding strongly to Salmonella pathogenicity islands 1 and 2 (SPI1 and SPI2); this offers the selective advantage of silencing foreign DNA while keeping it in the genome in case of need (PubMed:16933988).  DNA-binding influences plasmid DNA topology (PubMed:1423593).  For the proU locus (the proV-proW-proX operon) inhibits transcription at low osmolarity by binding to AT-rich, curved, DNA downstream of the transcription start site of proV; repression is greater when more than 1 curved DNA sequence is present (PubMed:1423593).  It plays a role in the thermal control of pili production (By similarity).  It is subject to transcriptional auto-repression (By similarity).  It binds preferentially to the upstream region of its own gene recognizing two segments of DNA on both sides of a bend centered around -150 (By similarity).
What are the official names of this protein?
DNA-binding protein H-NS, Histone-like protein HLP-II, Protein B1, Protein H1.
What is the protein family that this protein belongs to?
Belongs to the histone-like protein H-NS family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: Y179_UREPA
Sequence: MLIKPAKRSEKIYTIIAIKDSVVTLKNDYQDEKNIQIYEFDLQNIIPEVGKFINLIKYDQQGCSVFEEYDKNI
What are the official names of this protein?
Uncharacterized protein UU179.
Protein: Y1122_BACCZ
Sequence: MKLGIVIFPSKMIQDKANGLRKRYDPHYALVPPHITLKTPFETQDEQLESIVNELHTIASKTNPFTLHVGKVGSFAPVNNVIYFKVEKTPELTFLNEEMHSGFFTQEREYAFVPHLTIGQGLSDAEHADVLGRLRMKDFYYEQPIDRFHLLYQLENGTWTVHETFRLGKGNN
What are the official names of this protein?
Putative phosphoesterase BCE33L1122.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. YjcG family.
Protein: NTPP_CAUVC
Sequence: MSLTPVTLASQSSARQMILKNAGVAFEAVSPGVDEDAAKAGLLAEDVTPRDIADALAEMKAVKVSTKRPGLVIGADQTLDLKGRLIDKAGSLDEARARLLELRGTTHKLHSAVVVARDGRPIWRIVESAKLSVRPFSDAWLDRYIERRGEALLWSVGCYELESEGVQLFDKIEGDYFTILGLPLVGLLDFLRLHGALTV
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_BACC0
Sequence: MKKRALVSVSDKTGVVEFVKGLLEQGIEVISTGGTKKLLEENGLQVIGISEVTGFPEIMDGRVKTLHPNIHGGLLAVRDNETHVAQMNELGMEPIDFVVVNLYPFKETIAKPDVTFADAIENIDIGGPTMIRSAAKNHKFVSVIVDPVDYDVVLAELKENGEVAEETKRKLAAKVFRHTAAYDALISNYLTEQMGEESPETLTVTFEKKQDLRYGENPHQKATFYKAPFAATSSVAYAEQLHGKELSYNNINDADAALSIVKEFTEPAVVAVKHMNPCGVGVGTDIHEAYTRAYEADPVSIFGGIIAANREIDKATAEKLHEIFLEIIIAPSFSKEALEVLQSKKNLRLLTVNIEKATSASKKLTSVQGGLLVQEEDTLSLDESTISIPTKREPSEQEWKDLKLAWKVVKHVKSNAIVLAKDDMTIGVGAGQMNRVGSAKIAITQAGEKAQGSALASDAFFPMPDTVEEAAKAGITAIIQPGGSIRDEDSIKVADTYGIAMVFTGVRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: KU_KORVE
Sequence: MAASVWSGYLTFGLISMPVRLFSGARGSRISFNQLHREDHARVKQQLVCSADGKVLERDEIVKGYEYRKGEYVIIDPEELKKIEPKTAKSMEILEFVKAEEVDPVYFETSYYLQPDEGGEKPYALLVQALKESDYMGIAKVTMHNREYTVFLRPHTSGIMLHTMYYEDEVRKMEAPKITSEVKPAEVKIAHQLIEALAGKFEPEKFHDVYEANVKKLIEAHLEGQDVEAVAKPAKPAKVVDLMDALKQSLAAMKDQKKGSRLAEVDKESTVQMTPKKPAVKERRGRKRVA
What is the function of this protein?
With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity.  Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA.  Recruits and stimulates the ligase activity of LigD.
What are the official names of this protein?
Non-homologous end joining protein Ku.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic Ku family.
Protein: KEFF_SALTY
Sequence: MILIIYAHPYPHHSHANKRMLEQAGTLENVEIRSLYHLYPDFNIDVAAEQEALSRASLIVWQHPMQWYSVPPLLKLWMDKVLTHGWAYGHGGTALHGKHLLWAVTTGGGENHFAIGSHPGFDVLSQPLQATALYCGLKWLSPFAMHCTFICDDDTLQAQARQYKQRLLAWQEVNHG
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefC.  Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefF, Quinone oxidoreductase KefF.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PCR3_ARATH
Sequence: MASQHLQANPHAEGEWSTGFCDCFSDCQNCCITWLCPCITFGQVADIVDRGNTSCGTAGALYVLLAAITGCGCLYSCIYRGKIRAQYNIRGDGCTDCLKHFCCELCALTQEYRELKHRGFDMSLGWAGNVEKQQNQGGVAMGAPAFQGGMSR
What is the function of this protein?
May be involved in heavy metals transport.
What are the official names of this protein?
Protein PLANT CADMIUM RESISTANCE 3, AtPCR3.
What is the protein family that this protein belongs to?
Belongs to the cornifelin family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FEMX_STAAB
Sequence: MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEIQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSYERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
What is the function of this protein?
Catalyzes the incorporation of the first glycine of the pentaglycine interpeptide bridge, which is characteristic of the S. aureus peptidoglycan.  This glycine is added to the epsilon-amino group of the L-lysine of the membrane-bound lipid II intermediate (GlcNAc-(beta-1,4)-N-acetylmuramic acid(-L-Ala-D-iGln-L-Lys-D-Ala-D-Ala)-pyrophosphoryl-undecaprenol), using glycyl-tRNA(Gly) as donor, in a ribosome-independent mechanism (By similarity).
What are the official names of this protein?
Lipid II:glycine glycyltransferase, Factor essential for expression of methicillin resistance X.
What is the protein family that this protein belongs to?
Belongs to the FemABX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURI_STAAC
Sequence: MNKPIGVIDSGVGGLTVAKEIMRQLPNETIYYLGDIGRCPYGPRPGEQVKQYTVEIARKLMEFDIKMLVIACNTATAVALEYLQKTLSIPVIGVIEPGARTAIMTTRNQNVLVLGTEGTIKSEAYRTHIKRINPHVEVHGVACPGFVPLVEQMRYSDPTITSIVIHQTLKRWRNSESDTVILGCTHYPLLYKPIYDYFGGKKTVISSGLETAREVSALLTFSNEHASYTEHPDHRFFATGDPTHITNIIKEWLNLSVNVERISVND
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: TRPF_CAMJE
Sequence: MLKLKICGIKDEKNAKDLAFLNIDFFGLIFAKSPRRVSLEQARNLSAIFHEKDKKVVGVFVDENLEQILRCIKEAKLDGIQIYRTITKEEFEILKVQNVFVWQVISVENSLDLKSEIFANLVLFDAKGILKGGNGISFDWTLLGSYTKDFILAGGIGLDNVHKAVKTGAKILDLNSKLEDEKGLKDINKIKQILKELKK
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: DXO_RAT
Sequence: MEPRGTKRKAEKTEVAKTWNKLPRSLPSLRTQPSLYSGPFPFYRRPSELGCFSLDAQRQYHGDARALRYYSPPPINGPGPDFDLRDGYPDRYQPRDEEVRERLDHLLRWVLEHRNQLEGGPGWLAGATVTWRGHLTKLLTTPYERQEGWQLAASRFQGTLYLSEVETPAARAQRLARPPLLRELMYMGYKFEQYMCADKPGGSPDPSGEVNTNVAFCSVLRSRLGNHPLLFSGEVDCLNPQAPCTQPPSCYVELKTSKEMHSPGQWRSFYRHKLLKWWAQSFLPGVPYVVAGFRNPEGFVCSLKTFPTMEMFENVRNDQEGWNPSVCMNFCAAFLSFAQSTVVQDDPRLVHLFSWEPGGPVTVSVHRDAPYAFLPSWYVEAMTQDLPSLSKTPSPKD
What is the function of this protein?
Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.  The NAD-cap is present at the 5'-end of some RNAs and snoRNAs.  In contrast to the canonical 5'-end N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay (By similarity).  Preferentially acts on NAD-capped transcripts in response to environmental stress (By similarity).  Also acts as a non-canonical decapping enzyme that removes the entire cap structure of m7G capped or incompletely capped RNAs and mediates their subsequent degradation.  Specifically degrades pre-mRNAs with a defective 5'-end m7G cap and is part of a pre-mRNA capping quality control.  Has decapping activity toward incomplete 5'-end m7G cap mRNAs such as unmethylated 5'-end-capped RNA (cap0), while it has no activity toward 2'-O-ribose methylated m7G cap (cap1).  In contrast to canonical decapping enzymes DCP2 and NUDT16, which cleave the cap within the triphosphate linkage, the decapping activity releases the entire cap structure GpppN and a 5'-end monophosphate RNA.  Also has 5'-3' exoribonuclease activities: The 5'-end monophosphate RNA is then degraded by the 5'-3' exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs.  Also possesses RNA 5'-pyrophosphohydrolase activity by hydrolyzing the 5'-end triphosphate to release pyrophosphates (By similarity).  Exhibits decapping activity towards FAD-capped RNAs (By similarity).  Exhibits decapping activity towards dpCoA-capped RNAs in vitro (By similarity).
What are the official names of this protein?
Decapping and exoribonuclease protein, DXO, 5'-3' exoribonuclease DXO, Dom-3 homolog Z, NAD-capped RNA hydrolase DXO, DeNADding enzyme DXO.
What is the protein family that this protein belongs to?
Belongs to the DXO/Dom3Z family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRUA_LACLA
Sequence: MTRYKATIAYDGTDFAGFQSQTNQRTVQKEIEKILTKLNSFEPVILQGSGRTDSGVHAFGQVIHFDLKGKVRDLERLRFGLDTQTPADIAVKKVELVPDDWHARYQKHEKTYEYYLENSITRSPFQRHSKAYFRYPLNFERMQEAMSKLVGEHDFTGFTASGSSVDDKVRTIYQAEIIRLDEENFKFIFRGNGFLYKQVRNMVGTVIKIGNDRMPVSQIDKILTSKNRDFAGPTAAPEGLYLKEVKYAENTDI
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RS19_NEIG1
Sequence: MARSLKKGPYVDLHLLKKVDAVRASNDKRPIKTWSRRSTILPDFIGLTIAVHNGRTHVPVFISDNMVGHKLGEFSLTRTFKGHLADKKAKKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: KGUA_PSYCK
Sequence: MTGSLFIITAASGTGKTSLVKQLLATTNDLTVSVSHTTREPRPGEIDGHHYHFTDVNKFVTAISESQFLEHAEVFGNYYGTSEQSVRAQLDAGVDVILEIDWQGALQVKKIFTDAIMIFILPPSIATLRQRLSTRGQDSMEVIEQRLAGAVNEMAQYVNFDYVIINDSFEVALTELKAIIVADRQTLKRQQQRYQRTITNLLSNTVDE
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.