PharMolix/UniProtQA huggingface dataset:
Protein: EXSE_PSEAE
Sequence: MKIESISPVQPSQDAGAEAVGHFEGRSVTRAAVRGEDRSSVAGLARWLARNVAGDPRSEQALQRLADGDGTPLEARTVRRR
What is the function of this protein?
Acts as a negative regulator of the type III secretion regulon (T3SS) expression (PubMed:15911752).  In the absence of inducing signals such as low Ca(2+) or host cell contact, the T3SS/injectisome is expressed at a low basal level and exists in a quiescent state due to ExsA sequestration by ExsD.  ExsE binding to ExsC disrupts the complex between ExsC and ExsD, thereby allowing free ExsD to bind ExsA (PubMed:15911752, PubMed:15985546).  Upon inducing signal, ExsE is secreted allowing ExsC to bind ExsD.  In turn, ExsD cannot bind ExsA and prevent ExsA-mediated transcriptional activation of the type III secretion system (PubMed:15911752, PubMed:15985546).
What are the official names of this protein?
Type III secretion regulatory protein ExsE.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Note=Secreted under low-calcium conditions.
Protein: ATP7B_RAT
Sequence: MPEQERKVTAKEASRKILSKLALPTRPWGQSMKQSFAFDNVGYEGGLDSTCFILQLTTGVVSILGMTCHSCVKSIEDRISSLKGIVSIKVSLEQGSATVKYVPSVLNLQQICLQIEDMGFEASAAEGKAASWPSRSSPAQEAVVKLRVEGMTCQSCVSSIEGKIRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHICDMGFEAAIKNRTAPLRLGPIDINKLESTNLKRAAVPPIQNSNHLETPGHQQNHLATLPLRIDGMHCKSCVLNIEGNIGQLPGVQNIHVSLENKTAQVQYDSSCITPLFLQTAIEALPPGYFKVSLPDGLEKESGSSSVPSLGSSQRQQEPGPCRTAVLTITGIPRDSSVQPMEDMLSQMKGVQQIDISLAEGTGAVLYDPSVVSSDELRTAVEDMGFEVSVNPENITTNRVSSGNSVPQAVGDSPGSVQNMASDTRGLLTHQGPGYLSDSPPSPGGTASQKCFVQIKGMTCASCVSNIERSLQRHAGILSVLVALMSGKAEVKYDPEVIQSPRIAQLIEDLGFEAAIMEDNTVSEGDIELIITGMTCASCVHNIESKLTRTNGITYASVALATSKAHVKFDPEIIGPRDIIKVIEEIGFHASLAHRNPNAHHLDHKTEIKQWKKSFLCSLVFGIPVMGLMIYMLIPSSKPHETMVLDHNIIPGLSVLNLIFFILCTFVQFLGGWYFYVQAYKSLRHKSANMDVLIVLATTIAYAYSLVILVVAIAEKAEKSPVTFFDTPPMLFVFIALGRWLEHVAKSKTSEALAKLMSLQATEATVVTLGEDNLILREEQVPMELVQRGDIIKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSIVIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIISTLTLVVWIIIGFVDFGIVQKYFPSPSKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGVLIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRFLLLVDVATLSLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYSTDFQAVPGCGISCKVSNVESILAHRGPTAHPIGVGNPPIGEGTGPQTFSVLIGNREWMRRNGLTISSDISDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKPEAALASITLKSMGVDVALITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADVGIAIGTGTDVAIDAADVVLIRNDLLDVVASIHLSKRTVRRIRVNLVLALIYNMVGIPIAAGVFMPIGIVLQPWMGSAAASSVSVVLSSLQLKCYRKPDLERYEAQAHGRMKPLSASQVSVHVGMDDRRRDSPRATPWDQVSYVSQVSLSSLTSDRLSRHGGMAEDGGDKWSLLLSDRDEEQCI
What is the function of this protein?
Copper ion transmembrane transporter involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile.
What are the official names of this protein?
Copper-transporting ATPase 2, Copper pump 2, Pineal night-specific ATPase, Wilson disease-associated protein homolog.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Late endosome. Note=Predominantly found in the trans-Golgi network (TGN). Not redistributed to the plasma membrane in response to elevated copper levels.
Protein: RNFH_ERWT9
Sequence: MPDIAIEVVYALPEKQYLYNVKVPQGSSVEQAIIASGLLQLRPEIDLQENKVGIFSRPVKLHDEVNGGDRVEIYRPLIADPKDLRRQRAERAAKK
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: O5AK3_HUMAN
Sequence: MGRGNSTEVTEFHLLGFGVQHEFQHVLFIVLLLIYVTSLIGNIGMILLIKTDSRLQTPMYFFPQHLAFVDICYTSAITPKMLQSFTEENNLITFRGCVIQFLVYATFATSDCYLLAIMAMDCYVAICKPLRYPMIMSQTVYIQLVAGSYIIGSINASVHTGFTFSLSFCKSNKINHFFCDGLPILALSCSNIDINIILDVVFVGFDLMFTELVIIFSYIYIMVTILKMSSTAGRKKSFSTCASHLTAVTIFYGTLSYMYLQPQSNNSQENMKVASIFYGTVIPMLNPLIYSLRNKEGK
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Putative olfactory receptor 5AK3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AGP9_ARATH
Sequence: MARSFAIAVICIVLIAGVTGQAPTSPPTATPAPPTPTTPPPAATPPPVSAPPPVTTSPPPVTTAPPPANPPPPVSSPPPASPPPATPPPVASPPPPVASPPPATPPPVATPPPAPLASPPAQVPAPAPTTKPDSPSPSPSSSPPLPSSDAPGPSTDSISPAPSPTDVNDQNGASKMVSSLVFGSVLVWFMI
What is the function of this protein?
Proteoglycan that seems to be implicated in diverse developmental roles such as differentiation, cell-cell recognition, embryogenesis and programmed cell death.
What are the official names of this protein?
Classical arabinogalactan protein 9.
What is the protein family that this protein belongs to?
Belongs to the classical AGP family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: R13P3_HUMAN
Sequence: MLRHKTKRGHASLDCLKVFDGIPPPYDKKKRMVVPAALKVVRLKPTRKFALLGRQAQEVRWKYQAVTATLEEKRKEKAKIHYWKKKQLMRLRKQAEKNVKKN
What are the official names of this protein?
Putative 60S ribosomal protein L13a protein RPL13AP3, 60S ribosomal protein L13a pseudogene 3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: LOLD_KORVE
Sequence: MAKVFRSGSTDLRLFENLSFQVMKGEMVAIVGDSGSGKSSLLHILGALDRPSDGDVYFAELRLAKLSEAAAAEFRNRELGFVWQFHYLLPEFTALENIAMPLLVRGLGRREAETEARHWLNEVGLLDRGHHRPGELSGGEQQRVALARALVTRPKVLMADEPTGDLDNRTAETVFNLIARLHRDYQLTSLIVTHNLAFARRCDRVIRLAAGVVDEVEPQSLPA
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: KHSE_PSEAE
Sequence: MSVFTPLERSTLEAFLAPYDLGRLRDFRGIAEGSENSNFFVSLEHGEFVLTLVERGPVQDLPFFIELLDVLHEDGLPVPYALRTRDGEALRRLEGKPALLQPRLAGRHERQPNAHHCQEVGDLLGHLHAATRGRILERPSDRGLPWMLEQGANLAPRLPEQARALLAPALAEIAALDAERPALPRANLHADLFRDNVLFDGPHLAGLIDFYNACSGWMLYDLAITLNDWCSNTDGSLDPARARALLAAYANRRPFTALEAEHWPSMLRVACVRFWLSRLIAAEAFAGQDVLIHDPAEFEIRLAQRQNVEIHLPFAL
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: RL9_SHIFL
Sequence: MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNIEFFEARRAELEAKLAEVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADAVTAAGVEVAKSEVRLPNGVLRTTGEHEVSFQVHSEVFAKVIVNVVAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: YMGG_ECOLU
Sequence: MKKKILAFGLISALFCSTPAMADMNRTTKGALLGAGVGLLTGNGVNGVLKGAAVGAGVGAVTEKGRDGKNARKGAKVGAAVGAVTGVLTGNGLEGAIKGAVIGGTGGAILGKMK
What are the official names of this protein?
UPF0757 protein YmgG.
What is the protein family that this protein belongs to?
Belongs to the UPF0757 family.
Protein: Y640_SYNY3
Sequence: MAFLQTWLADYQIPLTLAVIVFALVMFVLEWLPIDTTAILVAVILMVLGLVTPTEGIAGFSNSATVTIMAMFILSYGITRTGIIQIIRDSLIKFGGDSLRRQLLLMGFIVGPSSAFLNNTAIVAIFLPIIEEWARQRQISVSKLLIPLSYATILGGMITLLGTSTNILASGLAEKLTGQGFSIFQFTPLGLLTFSVGLIYIVLAAPILLPARRNISDGNVAAEYQIKDYVSEIIIPPRSSLIGQTLRQSEIQRKFDIDVLEIIHNDTHFPQPLADRVLTMGDILLVRAGREDLLRIKDERGIEILADVQFVSAETNNAGPLESSEEKVAEVLILSNSRLIGSTLKDLRFRQRYNATVIAIRRGEELIRQRLGKVRLKFGDLLLLQGPRESFLGLQTTRELLVLEEKPLDNLRLDKAKTAIAIVALVIVIAGLDILPISVTSWAGVMAMVISGCLKPGEIYGAIRWDVIFLLAGLIPLGTAMENSGTTAWFASFLADAGGHLSGYALLLLFYLATALLTEILSNNATVVLMLPIAFQVAQSLGLNPLAFMFVVTFAASNSFMSPIGYQTNTMVYGPGGYRFTDFARIGAPLTVILTLATPLLVMLIYGVQPTN
What are the official names of this protein?
Uncharacterized transporter sll0640.
What is the protein family that this protein belongs to?
Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YA78_SCHPO
Sequence: MTSHQTGKIEVHWNDPSSGIFLSQTQRTSSTSSLKKSASSRRLVYGDDMLAPKPLAGQVLSKSPLPPFSPSKIMNRSISVPPTNISVPQISSNPLNLMKKSSDNDIFTTFNDTTNDCMNEASCEDVRHSLLQIIESKSNLSDSVHKMLGERVKTNLLLQGQLENMEGFWLQKLSQTCRLALTGNISEAKAFIVEIMCAGVVTNCVRWCPVLKTLIENLAI
What are the official names of this protein?
Uncharacterized protein C24H6.08.
Protein: FMT_GEOKA
Sequence: MTNIVFMGTPDFAVPILRQLLDDGYHVAAVVTQPDKPKGRKREPVPPPVKVEAERRGIPVLQPTKIREPEQYEQVLAFAPDLIVTAAFGQILPKALLDAPKYGCINVHASLLPELRGGAPIHYAIWQGKTKTGVTIMYMVERLDAGDMLAQVEVPIAETDTVGTLHDKLSAAGAKLLSETLPLLLEGNIAPVPQDEEKATYAPNIRREQERIDWTQPGEAIYNHIRAFHPWPVTYTTQDGHIWKVWWGEKVPAPRSAPPGTILALEENGIVVATGNETAIRITELQPAGKKRMAVGEFLRGAGSRLAVGMKLGEDHERT
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: OL472_MOUSE
Sequence: MEAENHTTVAELIILGLTEDPKLCIVFFVIFLGVYIITLVGNISIITLIRISSQLHTPMYLFLSHLAFVDIVFSTSVSVIMLMELLGHGLVLSVATCAAQLCMTVSFGSAECFLLAAMAYDRYVAICSPLLYSTLMSSRVCFLLLGISYVGGFVNGWTFTGCVLSLSFCGPTQINHFFCDFSPLLKVSCSDVSIIGIIPSISSGSIIVVTVFVIAVSYIYILITILKMRSTEGRHKAFSTCTSHLTAVTLFYGTITVIYVMPKSSYSTEQNKVISLFYTVVIPMLNPLIYSLRNRDVKDALRKAIVRVYS
What is the function of this protein?
Potential odorant receptor.
What are the official names of this protein?
Olfactory receptor 472, Olfactory receptor 204-5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MSCL_ECOSM
Sequence: MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLLTEIRDLLKEQNNRS
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL18_XANOP
Sequence: MSINKNIARLRRAKSTRSHIRDLGVARLSVLRTGQHLYAQVFTADGSKVIAAANTLQADVKDGLKNGKNSDAAVKVGKLIAERAKAAGIEKVAFDRSGYRYHGRIKALADAAREGGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: IF2G_METM7
Sequence: MAASNQSEVNIGMVGHVDHGKTSLTRKLTGVWTDTHSEELKRGISIRLGYADCEIKKCETCDEPECYTVDKKCDACGGKVSTLRKISFVDAPGHETLMATMLSGASLMDGAILVIAASEECPQPQTKEHLMALDALGVEHILIVQNKIDLVSEEAAIENYNQIKEFTKGTVAENAPIIPVSAHHGANLDVLLKAIQEFIPTPERDETLTPKLYVARSFDVNKPGSEIKDLKGGVIGGSIIQGALKVGDDLEIRPGIKVTEGNKTHWVPIVTKIISLGVGGKKLKSAAPGGLIGVGTELDPNLTKSDALSGSLAGLPGTLPETLEKMVIKPQLLERVVGSQDELIIEPLKTNEVLMLNVGTSTTVGVTVSARADKAEIKLKLPVCADKGDRVAISRKIGSRWRLIGYGIIL
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit gamma, aIF2-gamma, eIF-2-gamma.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
Protein: RL18E_METAC
Sequence: MGKKSLVKLTRKTNPRIVSLILTLKERANGDSAPIWKDIAKRLEAPSRNYAAVNISKINRHTAEDDVLLIPGKVLGAGLLDHPVTIAALTFSDSAFEKITEAGGKCLSLEEIMEANPKGSGIRIFR
What are the official names of this protein?
50S ribosomal protein L18e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL18 family.
Protein: MGRB_ECOLU
Sequence: MKKFRWVVLVVVVLACLLLWAQVFNMMCDQDVQFFSGICAINQFIPW
What is the function of this protein?
PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing.  MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway.  Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP.
What are the official names of this protein?
PhoP/PhoQ regulator MgrB.
What is the protein family that this protein belongs to?
Belongs to the MgrB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: GCSH_SHEB8
Sequence: MSNIPTELKYASSHEWIRKEEDGSYTVGITEHAQELLGDMVFVELPEVGDTVTAGEDCAVAESVKAASDIYAPISGEVIAVNEALEDSPELVNSSAYGEGWFFRVMPSDESEVDALLDAEGYQAVIDED
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: HIS5_DEIRA
Sequence: MSTTPVRAAPEVLLLDYGAGNVRSAARALERAGMTVRVTDNAADVPHAPALVVPGQGHFRQVMEAFEHGGFHGPVLDAARAGVPLLGICVGMQLLFDGSEEAPGVPGLGLIAGQVRKFAPAPERKVPQMGWNALEARGDSPLLRGLGPDAYAYFVHSYYVPVDVPVTDGAVTDYGVPFWSALSRGNLHAAQFHPEKSGAVGLALLANFRRELAPA
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPR21_HUMAN
Sequence: MNSTLDGNQSSHPFCLLAFGYLETVNFCLLEVLIIVFLTVLIISGNIIVIFVFHCAPLLNHHTTSYFIQTMAYADLFVGVSCVVPSLSLLHHPLPVEESLTCQIFGFVVSVLKSVSMASLACISIDRYIAITKPLTYNTLVTPWRLRLCIFLIWLYSTLVFLPSFFHWGKPGYHGDVFQWCAESWHTDSYFTLFIVMMLYAPAALIVCFTYFNIFRICQQHTKDISERQARFSSQSGETGEVQACPDKRYAMVLFRITSVFYILWLPYIIYFLLESSTGHSNRFASFLTTWLAISNSFCNCVIYSLSNSVFQRGLKRLSGAMCTSCASQTTANDPYTVRSKGPLNGCHI
What is the function of this protein?
Orphan receptor.
What are the official names of this protein?
Probable G-protein coupled receptor 21.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2880_SHEB2
Sequence: MQYQVDTHTHTVASSHAYSTIHDYIAVAKQKGIRLFANTDHGPAMADAPHFWHFVNLRVLPRMVDGVGILRGIEANIKNIDGEIDFFGDYLKQLDIVLAGFHEPVYPPSDKATHTEAMINAIKSGKVDIITHPGNPAYPIDIEAVARAAAEYGVALEINNSSFEVSRKGSEANCTAIAKAAKEFGTILVMGSDSHVAFSLGGFARAQAIIDEVAYPPSRLLNRSPSALLAFLAARGHETVADLIPLFSDDEPCC
What are the official names of this protein?
Probable phosphatase Sbal223_2880.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: CAD13_PONAB
Sequence: MQPRTPLVLCVLLSQVLLLTSAEDLDCIPGFQQKVFHINQPAEFIEDQSILNLTFSDCKGNDKLRYEVSSPYFKVNSDGGLVALRNITAVGKTLFVHARTPHAEDMAELVIVGGKDIQGSLQDIFKFARTSPVPRQKRSIVVSPILIPENQRQPFPRDVGKVVDSDRPERSKFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGAVGVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLGYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVNEGPVFYPDPMMVTRQENISVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLSVVILGASDKDLHPNTDPFKFEIHKQAVPDKVWKISKINNTHALVSLLQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSCRNSKVDSNAVGALRFSLPSLLLLSLFSLACL
What is the function of this protein?
Cadherins are calcium-dependent cell adhesion proteins.  They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.  May act as a negative regulator of neural cell growth (By similarity).
What are the official names of this protein?
Cadherin-13.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: URK_STACT
Sequence: MNATTIIGIAGGSGSGKTSVTNEILHNLEGHSVALIAQDYYYKDQSHLTFEERLKTNYDHPFAFDNDLLIQNLMDLRNGIPVEVPTYDYVNHTRSAETIAFQPKDVIIVEGIFALENKTLRDLMDVKIYVDTDADLRILRRLMRDTKERGRSMESVIEQYLNVVRPMHNQFIEPTKRYADIIIPEGGSNKVAIDIMTTKIQSLINNQQ
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_XYLFT
Sequence: MNDSSLSPEVTADLEYGLDILELDRAYVVPLLAYLTLLIRWNRTYNLTAIRDPREMVVRHLLDSLAIQRYVTVGRLADLGSGPGLPGIPLAISCPSLQVTLVESNGKKARFLREVVRQLGLSNVGVSEVRAEALDEALMYEHLTARALDTLNGIVTVGGHLLKSEGTLLAMKGAYPHEEIAMLPPHWVVEAVHRLQVPKLTGERHLVIVRKR
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_PYRHO
Sequence: MSKMTRHDAQLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKNVLGALERAMQHLKLYKQTPENGLALFVGNVSEIEGNTDIRLWAIIPPEPLNVRLYRCDQTFVTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIELLDELTSNVPGKTRAGGQSARRYERIREQETHEFMKRIGEHANRAFLPLLEKGELKGIIIGGPGPTKEEFVEGEYLHHELKKKILGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLATYGEREVRRALEIGAVDVLLISEGYNKVRVRVKCNHCGWEELKTMSEEEYEVYRKKITKCPKCGSQNLTIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI
What is the function of this protein?
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
What are the official names of this protein?
Peptide chain release factor subunit 1, Translation termination factor aRF1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_RHOBA
Sequence: MICLTPMVSLPLVTTTDSESTGPRKNHLLNWSLDQLKDWLQEQGQKPFRAKQIRRWLFSGRATSFEEMTDLPAKLRAQLEEHFAIFNATEAVVSKSKDGTEKILVRLADGGEVECVLLRDGPRRSICVSSQVGCAMGCVFCASGLDGVDRNLTGGEILEQMLRLQQRLPADERLSHIVMMGMGEPLANLPGVLSALDVARSEDGLGISPRRITISTVGLPPAIDKLAAAGIPYNLAVSLHAPNDELRSELVPVNRKIGIEPVLQAADRYFHASGRRLTFEYVLLGGINDGDEHARQLSQILRGRSVMMNVIPYNPVAGLPYRTPSGAAIARFRAILESAGVNVNFRQRKGDEINAACGQLRRNRGEVKATK
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIAD1_BOVIN
Sequence: MANLTGTIKGLYPETLSPEQLEKLRGFKIQTRITNEKYLRTHKEVELLISGFFREMFLKRPDNIPEFAADYFTDPRLPNKIHMQLIKEKKAA
What are the official names of this protein?
RIIa domain-containing protein 1.
Protein: RSMG_NOCSJ
Sequence: MTDDVSRETPSVPDVARRVFASDRLSLAERFVELLAGDGVVRGLIGPRETPRLWDRHLLNCALLAQQVPLEATVADLGSGAGLPGVVLAIARPDLRVTLVEPLLRRTTFLEEVVAELGLDRVEVLRARAEALHGDRRFAVVTSRALAPLDRLLGWSMPLVEPTGALLAMKGSAVAEEITAAGPELARWGCATPEVLSLGADLGLAPTVAVRVVWADPGRVSWPIAAPRKRGGQQRRAGHARGTSNRRRGT
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 518 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAR2_PROCL
Sequence: DRNFLRF
What is the function of this protein?
Increases the rate and amplitude of spontaneous contractions of semi-isolated hearts.  Increases the amplitude of excitatory postsynaptic potentials in abdominal extensor muscle.
What are the official names of this protein?
Cardio-excitatory FMRFamide homolog DF2.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: TSAC_WIGBR
Sequence: MLYFTIKNMKFRNLMKIINALREEEVVAYPTESMFGLGCDPDSISAVNKLIYLKKRKINKGFIIVAANISQLNNYIDCTSLSKNNLNKIFCTWPGFITWLMPPKKDIPCWLIGNNSLIAVRVSNFFPIKKICNIFGKPIISTSANLSGEIPAKNIKEIKHKLGSKIIILDHPIGKYSNPSEIRNGINYKIIRKG
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.