PharMolix/UniProtQA huggingface dataset:
Protein: CD2H_ASFB7
Sequence: MIIIVIFLMCLKIVLNNIIIWSTLNQTVFLNNIFTINDTYGGLFWNTYYDNNRSNFTYCGIAGNYCSCCGHNISLYNTTNNCSLIIFPNNTEIFNRTYELVYLDKKINYTVKLLKSVDSPTITYNCTNSLITCKNNNGTNVNIYLIINNTIVNDTNGDILNYYWNGNNNFTATCMINNTISSLNETENINCTNPILKYQNYLSTLFYIIIFIVSGLIIGIFISIISVLSIRRKRKKHVEEIESPPPSESNEEDISHDDTTSIHEPSPREPLLPKPYSRYQYNTPIYYMRPSTQPLNPFPLPKPCPPPKPCPPPKPCPPPKPCPPPKPCSPPKPCRPPKPCPPPKPCPPPKPCPPPKPCPPSKPCPSPESYSPPKPLPSIPLLPNIPPLSTQNISLIHVDRII
What is the function of this protein?
May play an immunosuppressive role by inhibiting lymphocyte proliferation and subsequently facilitating viral replication and generalization of infection (By similarity).  Responsible for viral hemadsorption, which may help viral spread (PubMed:8102411, PubMed:8615037).  Increases virus replication in the tick vector at the step of virus uptake or replication in the tick gut (PubMed:19729182).  May play a role in the host Golgi reorganization to yield viral factories (PubMed:25915900).  May play a role in host cell penetration (PubMed:34006158).
What are the official names of this protein?
CD2 homolog, CD2H, 5HL, CD2v, T-lymphocyte CD2 receptor-like protein, CD2-like protein, pEP402R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus CD2 homolog protein family.
What are the subcellular locations of this protein?
Host cell membrane; Single-pass type I membrane protein. Virion membrane. Host Golgi apparatus. Note=Localizes mainly around the perinuclear cytoplasmic viral factories which are probably derived from the host Golgi membrane (PubMed:25915900). Both proteolytic fragments localize to membrane compartements (By similarity). A minor fraction localizes on the host plasma membrane and on the outer viral envelope of budding particles (Probable).
Protein: RK23_MORIN
Sequence: MDGIKYFVVTDKSIRLLLKNQYTSNVESGSTRTEIKHWVELFFGVKVIAMNSHRLPGKGRRMGPIMGHTMHYRRMIITLQPGYYIPPLIKKST
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IHFA_RHILW
Sequence: MTGKTVTRADLAESVFRKVGLSRTESAELVETVIDEVCNAIVRGETVKLSSFATFQVRDKNERIGRNPKTGEEVPISPRRVMTFKASNVLKTRILKAHVARKVKLKPQNPAS
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: ATP23_YEAS8
Sequence: MNSSGDNAGFEWWRRTMQYKTGIGLTPEEKTRYEDDSKARELKKECLKCYEYRDWMLKYSPTVRFMVQAITKLNKGSDSKFDDSKIICDYCPDWKSGGFHPELGILLCQNRLRDKWHLEDTLSHELIHYFDDLKWQIDWLNLKHHACSEIRASSLSGECRFWEEFKRRGFRTGFHVARGHQDCVRRRAIISVSGNPNCQSKEHAAKIVDEVWDSCFADTRPFDEIYR
What is the function of this protein?
Has a dual role in the assembly of mitochondrial ATPase.  Acts as a protease that removes the N-terminal 10 residues of mitochondrial ATPase CF(0) subunit 6 (ATP6) at the intermembrane space side.  Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of ATP6 with the subunit 9 ring (By similarity).
What are the official names of this protein?
Mitochondrial inner membrane protease ATP23.
What is the protein family that this protein belongs to?
Belongs to the peptidase M76 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Associates loosely with the inner membrane.
Protein: HPPK_STRPY
Sequence: MTIVYLSLGTNMGDRAAYLQKALEALADLPQTRLLAQSSIYETTAWGKTGQADFLNMACQLDTQLTAADFLKETQAIEQSLGRVRHEKWGSRTIDIDILLFGEEVYDTKELKVPHPYMTERAFVLIPLLELQPDLKLPPNHKFLRDYLAALDQSDITLFSAQQTEF
What is the function of this protein?
Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.
What are the official names of this protein?
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, PPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK.
What is the protein family that this protein belongs to?
Belongs to the HPPK family.
Protein: RLMH_STRT2
Sequence: MKVKLITVGKLKEKYLKDGIAEYIKRLGRFTKFESIELTDEKTPDNASEAENKAILDKEGQRILAKVGDRDYVIALAIEGKQFPSEQFAKELEQATLRGYSDITFIIGGSLGLSPKVKKRANQLMSFGLLTFPHQLMRLILVEQIYRAFMIQQGSPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK13_TRICV
Sequence: MNETFIPASDYKKKNWCLIDCKDQKLGRIAVVISRLLSGKQKLHYHPAFDVGDYVVVINAQDMIFDSQQPRFSVNVPGRPGRLLKQVINALPSQLLMTAIYGMLPEGSAKKSLPKRLKIYNGPDHPHAAQNPIKLDEFI
What are the official names of this protein?
50S ribosomal protein L13, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EXPL3_DICDI
Sequence: MKFNTIFLVLSIVKFILISAQSCPFSQSIINGASATFYTAIDAGNCGFEKLNGPLGPGNYMIAALGSKLYQNGAQCGQCFKISNSKNASVTVMATDSCHDAGYCQRDNHFDLSPAAFSILGPQSQGVLDGLSYVKVPCEVSGNVKIMMKDGSNDFWTSFFVFNSKVIIKQVSIKLSNSNQFVPLSQTTYNYWPTSITGGQFHVRIESIGGEFIYVTIPKVESRKVYETSGQFSTSCSNLNENNPINYKPQTFNSQQTSNNQNSNTQTPTKQPSPNSQNFIPSYCQQYIQKPNYIFAKESKEMLVLNENENIESNSLKLLPNFLLLILIILLNINF
What is the function of this protein?
May serve to lubricate the movement of the cellulose microfibrils during cell growth and wall extension and/or may serve to maintain the fluid state of the slug cell wall.
What are the official names of this protein?
Expansin-like protein 3, Ddexpl3.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin A subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: IQD18_ARATH
Sequence: MGKKNGSSSWLTAVKRAFRSPTKKDHSNDVEEDEEKKREKRRWFRKPATQESPVKSSGISPPAPQEDSLNVNSKPSPETAPSYATTTPPSNAGKPPSAVVPIATSASKTLAPRRIYYARENYAAVVIQTSFRGYLARRALRALKGLVKLQALVRGHNVRKQAKMTLRCMQALVRVQSRVLDQRKRLSHDGSRKSAFSDSHAVFESRYLQDLSDRQSMSREGSSAAEDWDDRPHTIDAVKVMLQRRRDTALRHDKTNLSQAFSQKMWRTVGNQSTEGHHEVELEEERPKWLDRWMATRPWDKRASSRASVDQRVSVKTVEIDTSQPYSRTGAGSPSRGQRPSSPSRTSHHYQSRNNFSATPSPAKSRPILIRSASPRCQRDPREDRDRAAYSYTSNTPSLRSNYSFTARSGCSISTTMVNNASLLPNYMASTESAKARIRSHSAPRQRPSTPERDRAGLVKKRLSYPVPPPAEYEDNNSLRSPSFKSVAGSHFGGMLEQQSNYSSCCTESNGVEISPASTSDFRNWLR
What is the function of this protein?
May be involved in cooperative interactions with calmodulins or calmodulin-like proteins (By similarity).  Recruits calmodulin proteins to microtubules, thus being a potential scaffold in cellular signaling and trafficking (By similarity).  May associate with nucleic acids and regulate gene expression at the transcriptional or post-transcriptional level (By similarity).
What are the official names of this protein?
Protein IQ-DOMAIN 18, AtIQD18.
What is the protein family that this protein belongs to?
Belongs to the IQD family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nuclear body. Cytoplasm, cytoskeleton. Cell membrane.
Protein: NADD_GEOSL
Sequence: MKTGILGGTFNPVHVAHLRIAEEVRDTFALDRVLFIPAASPPHKAMEGEVPFETRCAMVRLATADNHAFAVSDMEGGRPGKSYSVDTIRALKEEYPGDEFFFIIGSDSFLDIGSWYDYEAIFASCNLVVAARPGAEAADLLAALPVAITAQFCYYPAEKRLAHRSGYSVYWLAGVPLDISSRSIRGLARLGRSIRYLVPEAVERYINEQRIYAHDG
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: KCNN4_MOUSE
Sequence: MGGELVTGLGALRRRKRLLEQEKRVAGWALVLAGTGIGLMVLHAEMLWFLGCKWVLYLLLVKCLITLSTAFLLCLIVVFHAKEVQLFMTDNGLRDWRVALTRRQVAQILLELLVCGVHPVPLRSPHCALAGEATDAQPWPGFLGEGEALLSLAMLLRLYLVPRAVLLRSGVLLNASYRSIGALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLTDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHNFMMDIHYAKEMKESAARLLQEAWMYYKHTRRKDSRAARRHQRKMLAAIHTFRQVRLKHRKLREQVNSMVDISKMHMILCDLQLGLSSSHRALEKRIDGLAGKLDALTELLGTALQQQQLPEPSQEAT
What is the function of this protein?
Forms a voltage-independent potassium channel that is activated by intracellular calcium (PubMed:9705284).  Activation is followed by membrane hyperpolarization which promotes calcium influx.  Required for maximal calcium influx and proliferation during the reactivation of naive T-cells (PubMed:20884616).  Plays a role in the late stages of EGF-induced macropinocytosis (By similarity).
What are the official names of this protein?
Intermediate conductance calcium-activated potassium channel protein 4, SK4, SKCa 4, SKCa4, IK1, KCa3.1, KCa4.
What is the protein family that this protein belongs to?
Belongs to the potassium channel KCNN family. KCa3.1/KCNN4 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KYNU_XANOR
Sequence: MTDLLSRAHADALDAADPLRSLRDAFVFPQHGDRDQTYLVGNSLGLQPRAARAMVDEVLDQWGTLGVEGHFTGPTQWLTYHQLVRDALARVVGAQPGEVVAMNTLSVNLHLMMASFYRPTHERGAILIEAGAFPSDRHAVESQLRLRGLDPATHLIEVEADEPNGTLSMAAIADAIAQHGPRLALVLWPGIQYRTGQAFDLAEIVRLARAQGAAVGCDLAHAVGNIPLTLHDDGVDFAVWCNYKYLNAGPGAVGGCFVHERHANSDLPRIAGWWGHEQQTRFRMDPQFVPSPGAEGWQLSNPPVLALAPLRASLTLFDQAGMAALRAKSERLTGHLEQLIRARVPQVLQIVTPAEPMHRGCQLSLRVAGGRAQGRSLFEHLHAAGVLGDWREPDVIRIAPVPLYNRFSDLHTFVGQVEAWAAA
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase, L-kynurenine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
Protein: NEP_I49A1
Sequence: MDSNTITSFQDILQRMSKMQLESSSVDLNGMITQFERLKIYRDSLGESVMRMGDLHSLQNRNATWREELSQKFEEIRWLIAECRNILTKTENSFEQITFLQALQLLLEVESEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: F149B_HUMAN
Sequence: MISRYTRKAVPQSLELKGITKHALNHHPPPEKLEEISPTSDSHEKDTSSQSKSDITRESSFTSADTGNSLSAFPSYTGAGISTEGSSDFSWGYGELDQNATEKVQTMFTAIDELLYEQKLSVHTKSLQEECQQWTASFPHLRILGRQIITPSEGYRLYPRSPSAVSASYETTLSQERDSTIFGIRGKKLHFSSSYAHKASSIAKSSSFCSMERDEEDSIIVSEGIIEEYLAFDHIDIEEGFHGKKSEAATEKQKLGYPPIAPFYCMKEDVLAYVFDSVWCKVVSCMEQLTRSHWEGFASDDESNVAVTRPDSESSCVLSELHPLVLPRVPQSKVLYITSNPMSLCQASRHQPNVNDLLVHGMPLQPRNLSLMDKLLDLDDKLLMRPGSSTILSTRNWPNRAVEFSTSSLSYTVQSTRRRNPPPRTLHPISTSHSCAETPRSVEEILRGARVPVAPDSLSSPSPTPLSRNNLLPPIGTAEVEHVSTVGPQRQMKPHGDSSRAQSAVVDEPNYQQPQERLLLPDFFPRPNTTQSFLLDTQYRRSCAVEYPHQARPGRGSAGPQLHGSTKSQSGGRPVSRTRQGP
What is the function of this protein?
Involved in the localization of proteins to the cilium and cilium assembly.  Indirectly regulates the signaling functions of the cilium, being required for normal SHH/smoothened signaling and proper development.
What are the official names of this protein?
Primary cilium assembly protein FAM149B1.
What is the protein family that this protein belongs to?
Belongs to the FAM149 family.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: LPXK_BRASO
Sequence: MREPAFWHRPPSWQSHLLSPLSMLYGAVAARRMAQPGIKAGVPVICVGNYHVGGAGKTPTVLALTALLRGQGEQPVVLSRGYGGRLPGPVLVDPAAHGAADVGDEPLMMAAHVPVVVSRARADGVGLAKAHRASVILMDDGFQNPSITKDLALIVVDGGRGLGNARVFPAGPLRTPLPPQLARTDALMIIGRGEAGEAVASRVAAAGKPVFRAQLQPDAGVVASLAGRPLLAFAGIGDPQRFFRSLRASGLEIRAERPFPDHHPFTDGDIKALVDQATREQLALVTTEKDLVRLRGRGWDHPELAPMAFPVTLQFDDETAVRSLVARRLSAARAS
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: UGTP_BACSU
Sequence: MNTNKRVLILTANYGNGHVQVAKTLYEQCVRLGFQHVTVSNLYQESNPIVSEVTQYLYLKSFSIGKQFYRLFYYGVDKIYNKRKFNIYFKMGNKRLGELVDEHQPDIIINTFPMIVVPEYRRRTGRVIPTFNVMTDFCLHKIWVHENVDKYYVATDYVKEKLLEIGTHPSNVKITGIPIRPQFEESMPVGPIYKKYNLSPNKKVLLIMAGAHGVLKNVKELCENLVKDDQVQVVVVCGKNTALKESLSALEAENGDKLKVLGYVERIDELFRITDCMITKPGGITLTEATAIGVPVILYKPVPGQEKENANFFEDRGAAIVVNRHEEILESVTSLLADEDTLHRMKKNIKDLHLANSSEVILEDILKESEMMTAKQKAKVLS
What is the function of this protein?
Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids.  Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl-sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta-triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol).  Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA).  Also seems to be able to form beta-tetraglucosyl-DAG, although this glycolipid has not been found in B. subtilis membrane.  UgtP can only use UDP-glucose as sugar donor.
What are the official names of this protein?
Processive diacylglycerol beta-glucosyltransferase, Beta-diglucosyldiacylglycerol synthase, Beta-DGS, DGlcDAG synthase, Glc2-DAG synthase, Beta-gentiobiosyldiacylglycerol synthase, Beta-monoglucosyldiacylglycerol synthase, Beta-MGS, MGlcDAG synthase, Beta-triglucosyldiacylglycerol synthase, TGlcDAG synthase, Diglucosyl diacylglycerol synthase (1,6-linking), Glucosyl-beta-1,6-glucosyldiacylglycerol synthase, UDP glucosyltransferase, UDP-glucose:1,2-diacylglycerol-3-beta-D-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. UgtP subfamily.
What are the subcellular locations of this protein?
Cell membrane. Note=Localized in both septal membrane.
Protein: CYB_ALCLI
Sequence: MTNIRKTHPLMEIINNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFLHVGRGLYYGSYAFLETWNVGVILLFATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPTGILSDADKIPFHPYYTIKDILGALLLILALMLLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRWIPNGLGGVLALALSILILVLVPLLHTSKQRSMMFRPISQCMFWILVADLLTLTWIGGQPVEHPYIIIGQLASLMYFLLILVLMPMASTIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GLNA_PINSY
Sequence: MSSVLTDLLNLDLSDVTEKVIAEYIWIGGSGMDMRSKARSLSGPVSSVKELPKWNYDGSSTGQAQGHDSEVILYPQAIFRDPFRRGKHILVICDAYSPNGTAIPSNKRAAAAKIFNEKAVSDEETWYGLEQEYTLLQKDVKWPLGWPIGGYPGPQGPYYCGVGADKAWGRDIVDAHYKACLYSGINISGINGEVMPGQWEFQVGPSVGISAADELWCARFIMERITEKAGVVLSFDPKPIEGDWNGAGCHTNYSTKSMRKEGGFEVIKKAIEKLKLRHKEHISAYGEGNERRLTGRHETADMNTFSWGVANRGASVRVGRDTEKEGKGYFEDRRPASNMDPYIVTSMIAETTILWKP
What are the official names of this protein?
Glutamine synthetase cytosolic isozyme, GS1, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZITB_SALTI
Sequence: MAHSHSHADSHLPKDNNARRLLFAFIVTAGFMLLEVVGGILSGSLALLADAGHMLTDAAALLFALLVVQFSRRPPTVRHTFGWLRLTTLAAFVNAIALVVITLLIVWEAIERFYTPRPVAGNLMMVIAVAGLLANLFAFWILHRGSDEKNLNVRAAALHVMGDLLGSVGAIVAALIIIWTGWTPADPILSILVSVLVLRSAWRLLKDSVNELLEGAPVSLDINALQRHLSREIPEVRNVHHVHVWMVGEKPVMTLHAQVIPPHDHDALLERIQDFLMHEYHIAHATIQMEYQMCHGPDCHLNQTPSGHVHHH
What is the function of this protein?
Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc.  It may contribute to zinc homeostasis at low concentrations of zinc.
What are the official names of this protein?
Zinc transporter ZitB.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CRK39_ARATH
Sequence: MGKYSVLMIFIASSLLIVLQNVEIVNAVGCTGSFFNGNSSYAQNRRDLFSTLPNKVVTNGGFYNSSLGKSPNIVHAVALCGRGYEQQACIRCVDSAIQGILTTTSCLNRVDSFTWDKDEEDNVSCLVSTSNHSTFGNLELRPSVRYQSPNSIEPSKNMTLFEQEWNAMANRTVESATEAETSSVLKYYSAEKAEFTEFPNVYMLMQCTPDITSQDCKTCLGECVTLFKEQVWGRQGGEVYRPSCFFRWDLYAFHGAFDNVTRVPAPPRPQAQGNESSITKKKGRSIGYGGIIAIVVVLTFINILVFIGYIKVYGRRKESYNKINVGSAEYSDSDGQFMLRFDLGMVLAATDEFSSENTLGQGGFGTVYKGTLLNGQEVAVKRLTKGSGQGDIEFKNEVSLLTRLQHRNLVKLLGFCNEGDEQILVYEFVPNSSLDHFIFDDEKRSLLTWEMRYRIIEGIARGLLYLHEDSQLKIIHRDLKASNILLDAEMNPKVADFGTARLFDSDETRAETKRIAGTRGYMAPEYLNHGQISAKSDVYSFGVMLLEMISGERNNSFEGEGLAAFAWKRWVEGKPEIIIDPFLIEKPRNEIIKLIQIGLLCVQENPTKRPTMSSVIIWLGSETNIIPLPKAPAFTGSRSQSEIGAMSMSDDVFTELSCR
What are the official names of this protein?
Putative cysteine-rich receptor-like protein kinase 39, Cysteine-rich RLK39.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CRK subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: HIS6_EDWI9
Sequence: MLAKRIIPCLDVRDGQVVKGVQFRHHEIIGDIVPLARRYADEGADELVFYDITASADGRVVDKSWVARVAAAIDIPFCVAGGIRSVKEAGLLLSYGADKISINSPALAEPTLITRLADRFGVQCVVVGIDTWHDAASDSDRVYQFTGDEARTRATAWQTADWVQEVQRRGAGEIVLNMMNQDGVRSGYDLRQLEQIRAVCRVPLIASGGAGAPEHFLAAFSQADVDGALAASVFHKQIIQIGELKRYLALNGVEIRLC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTHS_ACICJ
Sequence: MASDLDIARASRLRPIGEIAAAAGIPAEALIPYGRYKGKVDGGFIRSLEDRPDGALVLVVGISPTPAGEGKTTTSIGLGDALRAAGAKAMIALREPSLGPCFGQKGGATGGGRAQVAPMEEINLHFTGDFHAITSANNLLAAMLDNHVYWGNELGIDPRRIAFRRAIDMNDRALRQTVLGLGDGANGAAREQKFDITVASEVMAIFCLARDLDDLQRRLARIVVAERRDGSPVTPADLKAVGAMAALLRDALQPNLVQTLEGTPALVHGGPFANIAHGCNSVIATRTALKLADIVVTEAGFGADLGGEKFLDIKCRQAGLAPSCAVVVATIRALKMHAGVAKADLGAENPGAVARGAANLRRHVAAMRAFGLPVIVAINGFVTDTGAEREALRAALDEDGGARICFCTHWADGSAGATDLAQAVIETIAAKSARFAPLYPDDMKLPHKLRTIAQRIYGADDIELSPLAAKRLARFEAQGYDHLPVCVAKTQYSFTADPARRGAPTGFTVPIRDARLSAGAGFVVALAGDVMTMPGLPRIPAAEAIGLDPDGAIHGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: GLYA_LEPIN
Sequence: MQFLPKADPEIFAALKKEDERQENNLEMIASENFVSRAVLEAYTSTLTNKYAEGYPGKRYYNGCHNADVVETLAIERAKKLFGSQYANVQPHSGAQANMAVFLACLEPGDSFLGMNLAHGGHLTHGSPVNVSGKIYKPIPYGVDSKTETINYDEVAKLAREHKPKLIVAGASAYARTIDFSKFAEIAKEVGAKLMADIAHISGLVATGYHPSPIGMFDFVTTTTHKTLRGPRGGLILSTLENEKVLNSRVFPGIQGGPLMHVIAAKAVAFQEALQPDYKKYIETVLANAKTLAEVFVKRGYRVVSGGTDNHLVLLDVSVKGLTGAQAADGLDEVGVTVNKNAIPFDKNPPAVASGIRLGTPALTTRGLKPADMETVGNLICDFLDHPNDDKNRTKVKGGIQEMTQKFPMNQFRLD
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_PARUW
Sequence: MIMGQYLFWLANAHEPIENRIPELPNFISVLYHRFQHTTWAQFLHRWENIIFAILVASLISLVAYLGARKKEIIPSKFQNLLEIAVEKFSHLILEVLGPEGKAYIPFLGTLFIYIFTMNIFGMVPLMKAPSSSLNITAALAICVFCLVQFLNIRNMGIFGFLYHLAGSPKSMLEWLLAPLMFSLEIISQLSRPLTLALRLFGNVLGEDILIGTFALMGVVMISSVETFVGIPLQLPFMFLGLLTSFMQALVFTLLSTVYILLSMHKEGEKN
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRB_GLUDA
Sequence: MTDGPRAAAPRFFPQHARHLLGLQGMHPTRIEPFLDLAESYALMSRSRKTPRDRLLGRTVINLFFEDSTRTRTSFELAAKRLGADVINMTVASSSVNKGETLLDTAATLNAMRTDLLVVRHSQSGAPALLARKVEASVVNAGDGTHEHPTQALLDALTIRRHFGTLHGLTVAICGDVSHSRVARSNIHLLTAMGARVRVVGPPTLIPGAIGALGVDVHYTMEDGLRDVDVVMMLRMQRERMSGGQVPSAREYFRFYGLDRKRLAVARPGALVMHPGPMNRGVEIDSRVADSDQSVIREQVEMGVAVRMAVLDLLSRAGDQS
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.