PharMolix/UniProtQA huggingface dataset:
Protein: ARCA_PSEMY
Sequence: MSKKALGVHSEAGKLHKVMVCSPGLAHLRLTPNNCDELLFDDVIWVSQAKRDHFDFMTKMRERGIEVVEMHNLLEETVRDPQALKWILDRKITPNSVGLGLQGEVRSFIEGLEPRRIAEFLIGGVSGADLAKHKDSEAAKMFNAYLGESSFIFPPLPNTQFTRDTTCWIYGGVTLNPMYWPARRQETLLTSAIYKFHPDFAGEQFEIWYGDPDQDHGAATLEGGDVMPIGNGTVLIGMGERTSHQAIGQVARALFAKGAAQRVVVAGLGKSRAAMHLDTVFSFCDRDLVTIFPEVANSIVPFSLRPDESRPGGIDVRREDKSFLDVVAESLNLPKLRVVETGGDAYEAEREQWDDGNNVVCLEPGVVVGYDRNTYTNTLLRKAGVEVITISASELGRGRGGGHCMTCPIIRDPIDY
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BPHA1_PSES1
Sequence: MGIYSEREVQAVPMTFKRRWTDEAIRALVDQDKGLIDPRIYADQDLYEIELERIFARSWLLLGHEAHIPKTGDYLTTYMGEDPVIMVRQKDGSIKVFLNQCRHRGMRICRSDAGNAKAFTCTYHGWAYDIAGNLVNVPYEKEAFCDKKEGDCGFDKADWGPLQARVETYKGLIFANWDAEAPDLKTYLSDAMPYMDVMLDRTEAGTTVVGGMQKWVIPCNWKFAAEQFCSDMYHAGTMAHLSGVLSSLPPEMDLTQVQMSKNGSQFRAAWGGHGSGWFINDAAILMAVMGPKITQYWTQGPAAEKAAKRLNQMPTQTMFGQHMTVFPTCSFLPGINTIRSWHPRGPNEVECGPSWSSMPMRPEDIKEEFRRQNIRTFNAGGTFEQDDGENWVEIQRGLRGHKAKSAPLCAQMGLNVPNKSNPDFPGKTAYVYAEEAARGMYHHWARMMSEPNWETLKP
What are the official names of this protein?
Biphenyl dioxygenase subunit alpha, Biphenyl 2,3-dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.
Protein: UREE_HELHP
Sequence: MRVEHIIGNIKDIDATHLDIDEVQIAWYDTKKKIARLNSQNGQVIAMKLAQAPKYGLNNGDILFLDEHKIIIISILPTWVLCMKPTHWHTMARLCYEIGNLHIPLFYNKDTMKLQAPFEQPLQRILEKQSIAFEKKWCVLDSKDRINITYPIASEPKLIQSPHFSIKITQKGLN
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1753_LACPL
Sequence: MSRLWLSGYRSYELNVFGDQDDKLKVIKFALTNYLTTQIEDGMDWLITGGQLGIEQWTAEVGLTLKKTYPELKVAMMLPYGEFGGRWNENNQAKLQTLLAQVDFHAPVSKQPYENPQQLKNYQEFMVTHTDAATLVYDPDNPGKPTYDYDLIRNFSDTHPYPLTLIDFDWLQESANEYAEKQNNGFNFE
What are the official names of this protein?
UPF0398 protein lp_1753.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: RPOY_BACC4
Sequence: MIFKVFYQEKLTEVPVRENTKVLYLEATSEKDVRTKLNKFAYNIEFVQSVTGAHLEYEKENADLTLAEIV
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: GIGAN_ORYSJ
Sequence: MSASNEKWIDGLQFSSLFWPPPQDSQQKQAQILAYVEYFGQFTADSEQFPEDIAQLIQSCYPSKEKRLVDEVLATFVLHHPEHGHAVVHPILSRIIDGTLSYDRNGFPFMSFISLFSHTSEKEYSEQWALACGEILRVLTHYNRPIFKVDHQHSEAECSSTSDQASSCESMEKRANGSPRNEPDRKPLRPLSPWITDILLAAPLGIRSDYFRWCGGVMGKYAAGGELKPPTTAYSRGSGKHPQLMPSTPRWAVANGAGVILSVCDEEVARYETANLTAAAVPALLLPPPTTPLDEHLVAGLPPLEPYARLFHRYYAIATPSATQRLLFGLLEAPPSWAPDALDAAVQLVELLRAAEDYDSGMRLPKNWMHLHFLRAIGTAMSMRAGIAADTSAALLFRILSQPTLLFPPLRHAEGVELHHEPLGGYVSSYKRQLEVPASEATIDATAQGIASMLCAHGPDVEWRICTIWEAAYGLLPLSSSAVDLPEIVVAAPLQPPTLSWSLYLPLLKVFEYLPRGSPSEACLMRIFVATVEAILRRTFPSETSEQSRKPRSQSKNLAVAELRTMIHSLFVESCASMDLASRLLFVVLTVCVSHQALPGGSKRPTGSDNHSSEEVTNDSRLTNGRNRCKKRQGPVATFDSYVLAAVCALSCELQLFPFISKNGNHSNLKDSIKIVIPGKTTGISNELHNSISSAILHTRRILGILEALFSLKPSSVGTSWSYSSNEIVAAAMVAAHVSELFRRSRPCLNALSALKQCKWDAEISTRASSLYHLIDLHGKTVTSIVNKAEPLEAHLTLTPVKKDEPPIEEKNINSSDGGALEKKDASRSHRKNGFARPLLKCAEDVILNGDVASTSGKAIASLQVEASDLANFLTMDRNGGYRGSQTLLRSVLSEKQELCFSVVSLLWQKLIASPEMQMSAESTSAHQGWRKVVDALCDIVSASPTKASAAIVLQAEKDLQPWIARDDEQGQKMWRVNQRIVKLIAELMRNHDSPEALVILASASDLLLRATDGMLVDGEACTLPQLELLEVTARAVHLIVEWGDSGVSVADGLSNLLKCRLSTTIRCLSHPSAHVRALSMSVLRDILNSGQINSSKLIQGEHRNGIQSPTYQCLAASIINWQADVERCIEWEAHSRRATGLTLAFLTAAAKELGCPLTC
What is the function of this protein?
Involved in regulation of circadian rhythm, and in the control of the photoperiodic flowering.  Acts as suppressor of flowering under short-day (SD) and long-day (LD) conditions.  Activates Hd1/CONSTANS gene.
What are the official names of this protein?
Protein GIGANTEA.
What is the protein family that this protein belongs to?
Belongs to the GIGANTEA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TIM22_CRYNJ
Sequence: MSIPLPSAMPLLPPIYLPGQEPLPAGTSDWERQEMQTALKYQRYMGMVMESCPLKVTIAGVGGLAIGGFFSLMSATFAYEDPLSRASNKLTTTRAQTMFVFKEMGRNMWSSGRGFAKVGMVYSGVECCIEGYRAKNDIYNGVSAGFLTGAILARNAGPTAMLGGGVAFAAFSGAIDWWLRSAPADEI
What is the function of this protein?
Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel.  Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM22.
What is the protein family that this protein belongs to?
Belongs to the Tim17/Tim22/Tim23 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GLMM_THENN
Sequence: MKVRYFGTDGIRGVFGDTLTDELAFKVGKALGEIVGEGKVLIGKDTRVSGDSLEAALAAGLTSMGVDVLSCGILPTPAVALLTRITRSYGVVISASHNPPEYNGIKVLKNGYKIPDELEEEIERRMEGEFQRRYVVGKIKSFREGKDMYIGAVLEMFKDLDLSGKSVSLDLANGATTTTAKDVFEFLGAEVEVFNSSQDGLLINQGCGATHPKFLAEEMKRGRIGFSFDGDGDRVIAVDEERNVVNGDKIIGILAEGMMEEGRLRESVVVGTIMTNGGLEEYLRKRGIELVRTKVGDKYVLEEMLKSGANLGGERSGHIIILDRSTTGDGLITALELMRVVERLKKNLSDLAKEIPDLPQITRNVRRTEKTSLENGRLRELIERYSAEGYRIVVRPSGTEPVVRITVEGKDRNRVEEIAEELSRILEG
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RLMM_SHESH
Sequence: MINLFLFCRAGYEKECAAEIQHRAAELDIGGFVKTNKNDAYVIFQCFQAGDAAVLAQKIKLDSLIFARQMFAAKALLKNLPENDRITPIMEALSDVRNAGELRVETPDTDAAKERTTFCRKFTVPLRQKLKNSGNLLKKESSSRPIIHVCFVASGTAYVGFSFSNNSSPYPMGIPRLKMASDAPSRSTLKLDEAFIHFIPEEEKELRLSSGMNAVDLGACPGGWTYQLVRRGMFVAAIDNGAMDEGLMETGQVKHYQADGFRFEPPRKNIYWLVCDMIEKPSRVAELIEAWAINGWFKEAMFNLKLPMKSRYQDVTTILETMATVLKENEIKNFSIKCKHLYHDRDEVTVYLSLNPTQVS
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_KORVE
Sequence: MARYKDAVCRLCRREGTKLFLKGPKCFTDKCAIEKRNFAPGQHGKDRKAKIVGYGLQLREKQKTKRMYFAQENQFRNYFEKAAKGQGVTGEMLLQQLERRLDNVVYRLGFASARRQARQLVRHGHIAVNGKKVNIPSYQVSVKDEIAVREGSKEMTLLGQIKELTSHTTVPGWLIVDRDNWKGSVSSLPRRDEIQMPVNEQLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: NDVA_AGRFC
Sequence: MTLFQVYTRALRYLTVHKWRVAVVVIANVILAAITIAEPVLFGRIIDAISSGTNVTPILILWAGFGVFNTVAYVAVAREADRLAHGRRATLLTEAFGRIISMPLSWHHLRGTSNALHTLLRASETLFGLWLEFMRTHLATFVALVLLIPTAMAMDLRLSFVLIGLGIVYWFIGKWVMGRTKDGQASVEEHYHSVFAHVSDSISNVSVLHSYNRIEAETKALKSFTEKLLSAQYPVLDWWAFASALNRTASTVSMMIILVIGTVLVKNGELRVGDVIAFIGFANLLIGRLDQMRQFVTQIFEARAKLEDFFVLEDAVKEREEPGDARELSNVSGTVEFRNINFGFANTKQGVHDVSFTAKAGETVAIVGPTGAGKTTLINLLQRVYDPDSGQILIDGTDISTVTKNSLRNSIATVFQDAGLLNRSIRENIRLGRETATDAEVVEAAAAAAATDFIDSRINGYLTQVGERGNRLSGGERQRIAIARAILKNAPILVLDEATSALDVETEARVKAAVDALRKNRTTFIIAHRLSTVRDADLVLFLDQGRIIEKGTFDELTQRGGRFTSLLRTSGLLTEDEGQQPRPKAIAS
What is the function of this protein?
Involved in beta-(1-->2)glucan export which is required for crown gall tumor formation.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity).
What are the official names of this protein?
Beta-(1-->2)glucan export ATP-binding/permease protein NdvA, Attachment protein.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Beta-(1-->2)glucan exporter (TC 3.A.1.108.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL3_YERPY
Sequence: MIGLVGKKVGMTRIFTEDGVSIPVTVIEIEANRVTQVKSLENDGYRAVQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLPEGQEFTAGQEISVEIFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGHMGDERVTVQSLDVVRVDAERNLLLVKGAVPGATGGNLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: SOMA_CHEMY
Sequence: AFPAMPLSSLFANAVLRAQHLHLLAADTYKEFERTYIPEEQRHSNKISQSASCYSETIPAPTGKDDAEQKSDMELLRFSLILIQSWLNPVQFLSRVFTNSLVFGTSDRVYEKLRDLEEGIQALMRELEDGSLRGFQVLRPTYDKFDINLRNEDALLKNYGLLSCFKKDLHKVETYLKLMKCRRFGESNCTI
What is the function of this protein?
Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes.  Implicated as an osmoregulatory substance important for seawater adaptation.
What are the official names of this protein?
Somatotropin, Growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RH13_ORYSJ
Sequence: MAAAPPPPPPPQLQSSDPSTPPQETSQVRKGKKSRGAKKPRRAAAAAAASTSSAGTMVEDPFLVLAGGKEGGFLELEEIDEADFGIFGGAVEDLGEIDRKAGKDQKKKKRKKRKRGDDDYALPGDGDLVVECEEEGEKGEKRVKKKRRSRKKRKVKEMEEKMESKEDVSDDNVEDMQDGNDMEQDNNDGLILGEDEVYAWRELRLHPLLITAVRRLGFKEPTPIQKACFPAAAHQGKDVIGAAETGSGKTLAFGLPILQRLLEEQEKAMRLSREDESTQDENSRESPLRALILTPTRELAKQVCDHLKEAAKFLRIQVVPIVGGLSMEKQERLLKRKPEIVVGTPGRLWELMSTGNQHLIKLHSLSFFVLDEADRMIERGHFHELQSIIEMLPVTNGSDEQTVGTTPSCETVPILQIKKRQTFVFSATLALSANFRKKLKRGLVTAKASASTDLSSIEALSKQARMKPNAEIVDLTKASILPEKLEESFIECSDDDKDAYLYYILSVHGQGRTIIFCTSIAALRHLSSILRVLGINVLTNHAQMQQRARMKAVDRFRESENSILVATDGFARGMDFDDVRTVIHYQLPHSTDVYIHRSGRTARKSMAGCSIALISPADKAKFYSLCKSLSKENLQQFPVDHAYMPAVMNRLTLARQIDKITRKNSQENANKSWLQRNAESMGLLLETSDSEEERVQGHKQRKATSANLQKLQQDLSELLQRPLQPKTFSRRYLAGAGVSPLLQKQLEELSKRNVKGSASVNANKGSRFVVIGQDQIEPLQALQNSGQEVCVSIDKQREKRRLAENWRRKKQKEKKSTREQKRKEKRIAKERD
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 13.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX24/MAK5 subfamily.
Protein: SYK_HELPY
Sequence: MFSNQYIQQRIHKANSLREEGKNPYQNGLKRSLTNAAFLEKYAYVKGLEEPKDKEKCESIVGRVKLLRLMGKACFIKVEDESTILQVYVSQNELNDEFKSLKKHLEVGDIVLVKGFPFATKTGELSIHALEFHILSKTIVPLPEKFHGLSDIELRYRQRYLDLIVNPSVKDVFKKRSLIVSSVRKFFEMEGFLEVETPMMHPIPGGANARPFITYHNALEVERYLRIAPELYLKRLIVGGFEAVFEINRNFRNEGMDHSHNPEFTMIEFYWAYHTYEDLIELSKRLFDYLLKTLNLDSKIIYNDMEVDFNQTSVISYLDALETIGGISKDILEKEDRLLAYLLEQGIKVEPNLTYGKLLAEAFDHFVEHQLINPTFVTQYPIEISPLARRNDSNPNIADRFELFIAGKEIANGFSELNDPLDQLERFKNQVAEKEKGDEEAQYMDEDYVWALAHGMPPTAGQGIGIDRLVMLLTGAKSIKDVILFPAMRPVKNDFNVESEE
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_SHEPA
Sequence: MNLADKVLVVNDNLPIRTDKPVHSGKVRSVYWLTEEDSARLIKDKGYDVPADAPLAIMVISDRISAFDCVWQGENGLNGVPGKGTALNAISNHWFKLFKDKGLADSHILDIPHPLVWIVQKARPVMIEAIARQYITGSMWRSYTKGEREFCGITIPEGLEKDQKLPELLITPSTKGVLTGLEGVPEADDVNVSRSDIERHVKGFNFSNESDIDLYEKLLKEGFDVISDALAEHDQIFVDTKFEFGYVNDAAGNEKLIYMDEVGTPDSSRIWDGSSHRDGKIIEQSKEGFRQWLLNHFPDPDILLNKNRMVERFALASDNKLPESVMMDISNTYVGIAEKIIGKKLHISDNPKQEIIDILRDEYQLIV
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: MPP10_MOUSE
Sequence: MAPRVFRRQTLERCLREIRKATNRPECFLTIQNGLASNFTSLTKVLYDFNKVLENGRISGSPLQKLEINSFDDEQIWQQLELQNEPVLQYFQNAVSETVEDEDISLLPECEDEECEEDASEVEADNQENLETDLDEEQLSDEGGDVPKGRDRAKSSRKSDPRKSPVFSDEDSDLDFDIGKLEQQTKMQIKPPGKPREKSVVDDKFFKLSEMESFLEKVEKEEEKRPDGEEEDEEDIDLFEDIDSDESEGGLFGRQKIKSNKSSRNLKYKDFFDPVESDEDITGVDEELGPDEEKEEEEGFAEEADESISDTDEDNDLEEDENSDQHKGSLKRVTFALPDDEAEDTSPLAVKQESDEVKSSFEKRQEKMNEKIASLEKELLDKKPWQLQGEVTAQKRPENSLLEETLHFDHAVRMAPVITEETTLHLEDIIKQRIRDQAWDDVERKEKPKEDAYEYKKRLTLDHEKSKLSLAEIYEQEYLKLNQQKTEEEDNPEHVEIQKMMDSLFLKLDALSNFHFIPKPPVPEIKVVSNLPAITMEEVAPVSVSDAALLAPEEIKEKNKAGDLKTAAEKTATDKKRERRKKKYQKRLKIKEKEKRKKLLEKNNPDQSKSSRAAASEKLKQLTKTGKVSLLKDERKDKPLKSSQAFFSKLQDQVKMQINDAKQPEKIKKKKQDISVHKLKL
What is the function of this protein?
Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP).  Required for the early cleavages during pre-18S ribosomal RNA processing.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
U3 small nucleolar ribonucleoprotein protein MPP10, M phase phosphoprotein 10.
What is the protein family that this protein belongs to?
Belongs to the MPP10 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Chromosome. Note=Fibrillar region of the nucleolus. After dissolution of the nucleolus in early M phase becomes associated with chromosomes through metaphase and anaphase. In telophase localized to small cellular prenucleolar bodies that not always contain fibrillarin. The reassociation with nucleolus is preceeded by the arrival of fibrillarin.
Protein: UGDH1_ORYSJ
Sequence: MVKICCLGAGYVGGPTMAVIALKCPDVEVVVVDISAARIDAWNSDALPIYEPGLDDVVRRCRGRNLFFSSDVERHVGEADIVFVSVNTPTKARGLGAGKAADLTYWESAARMIAAVATSDKVVVEKSTVPVKTAEAIEKILDHNGRDGVGFQILSNPEFLAEGTAIRDLLAPDRVLIGGRETAAGRAAVQALKDVYTRWVPEERILTTNLWSAELSKLAANAFLAQRISSVNAMSALCEATGADVAEVAYAVGKDSRIGAKFLNASVGFGGSCFQKDILNLVYICECNGLPEVANYWKQVIKINDYQKSRFVNRVVSSMFNTVAGKKIAVLGFAFKKDTGDTRETPAIDVCKGLIGDKAKVSIYDPQVTEDQVQRDLAMSKFDWDHPVHLQPMSPTAIKQVSVAWDAYEAARAAHGVCILTEWDEFRSLDYARIYGGMQKPAFVFDGRNVVDAEKLREIGFIVYSIGKPLDAWLKDMPAVA
What is the function of this protein?
Involved in the biosynthesis of UDP-glucuronic acid (UDP-GlcA), providing nucleotide sugars for cell-wall polymers.
What are the official names of this protein?
UDP-glucose 6-dehydrogenase 1, UDP-Glc dehydrogenase 1, UDP-GlcDH 1, UDPGDH 1, Os-UGD1.
What is the protein family that this protein belongs to?
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
Protein: NUOH_PARXL
Sequence: MSLFDTINSGGTQLLGVAWPTVWALVRILVVAVVILLCVAYLILWERKLIGWMHVRLGPNRVGPAGLLQPIADVLKLLLKEVIQPAQASRWIYMVAPIMVVVPAFAVWAVIPFQAGAVLGDINAGLLYAMAVSSIGVYGVILAGWASNSKYAFLGAMRAAAQMVSYEISMGFALVVVLMTAGTLNLSGIVGSQEHGFFASHGLNFLSWNWLPLLPMFVVYFISGIAETNRHPFDVVEGESEIVAGHMIDYSGMAFALFFLAEYINMIVISALAATLFLGGWSAPFGFLSFIPGIVWLVAKVFFLLSVFIWARATFPRYRYDQIMRLGWKIFIPVCVVWLVVVGFWIMSPLNIWK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PTN6_MOUSE
Sequence: MVRWFHRDLSGPDAETLLKGRGVPGSFLARPSRKNQGDFSLSVRVDDQVTHIRIQNSGDFYDLYGGEKFATLTELVEYYTQQQGILQDRDGTIIHLKYPLNCSDPTSERWYHGHISGGQAESLLQAKGEPWTFLVRESLSQPGDFVLSVLNDQPKAGPGSPLRVTHIKVMCEGGRYTVGGSETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKSKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYVKNQLLGPDENSKTYIASQGCLDATVNDFWQMAWQENTRVIVMTTREVEKGRNKCVPYWPEVGTQRVYGLYSVTNSREHDTAEYKLRTLQISPLDNGDLVREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMESISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEIIQSQKGQESEYGNITYPPAVRSAHAKASRTSSKHKEEVYENVHSKSKKEEKVKKQRSADKEKNKGSLKRK
What is the function of this protein?
Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR.  Enhances the inhibition of mast cell activation mediated by the Lilrb4a receptor (PubMed:10026201).  The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates.  Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation.  Plays a key role in hematopoiesis.
What are the official names of this protein?
Tyrosine-protein phosphatase non-receptor type 6, 70Z-SHP, Hematopoietic cell protein-tyrosine phosphatase, PTPTY-42, Protein-tyrosine phosphatase 1C, PTP-1C, SH-PTP1, SHP-1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=In neurons, translocates into the nucleus after treatment with angiotensin II. Shuttles between the cytoplasm and nucleus via its association with PDPK1 (By similarity).
Protein: MON1_NEUCR
Sequence: MDRDTEAGSNDGTNDNNDTTIPPHTPESNIEAVDHVPPVPRRPSPKLSDDGASGALHVAAASRPTTQVSTIDISTLSFPDGSRGTFSTSATSATSATSATRSVASPQSSASGYTSPRTDLVETVSVASYPATLRPPGDLADLVTGEFNRRSRAWSMLRTQSSSVQPFEASRTGACDSLTGFEKEFDNIPELGEKGITDEQRLSLWKSKMKHYMILSSAGKPIWSRHGDTSLINSYMGVVQTIISFYEGAKDPLLGFTAGNARFVISTQGPLYFVAISRLGESDAQLRSQLDALYMQILSTLTLPTLKNIFVHRPSTDLRKPLEGTESLLSSLADSFTKGSPSALLGALECLRLRKSHRATINNAFLKCRSDKLLYGLIVAGGKLVSVIRPRKHSLHPSDLQLIFNMLFESGGIRAGGGENWVPLCLPAFNNRGYLYMYVSFFDSVETAEENNSNNTNNPEQPPQPPPPKPVTSPDEEIAIILISADKESFFELKSMRDKLALQLAKNGSLALIQSAARQGRPRIETILNTKPLSKEAGQGQGQGQLSHFLYKSRANVQFCQSSLSPAFETSSPPLPSSSPSENGSSQKTTEKLVSRRRLMTLYHHLHASIHAKHSHLKVLHLVSEDAASLAWITPVFEFYCVAGPNMSSGIMTQCANKVVQWAKREEERLFIIGGGVF
What is the function of this protein?
Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.
What are the official names of this protein?
Vacuolar fusion protein mon1, Autophagy-related protein 13.
What is the protein family that this protein belongs to?
Belongs to the MON1/SAND family.
What are the subcellular locations of this protein?
Endosome, multivesicular body membrane; Peripheral membrane protein. Prevacuolar compartment membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Protein: BKRB2_PIG
Sequence: MLNLTSQVPEPALNGTLPQSSSCFHSDWWNWLNTIQAPFLWVLFLLAALENIFVLSVFCLHKNSCTVAEIYLGNLAMADLILALGLPFWAITIANHFDWLFGEVLCRVVNTMIYMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCTLLLSSPMLAFRTMHEYAAEGHNVTACIIKYPSRSWMVFTNILLNSVGFLLPLSIITYCTVQILQVLRNNEMQKFKEIQTERKATVLVLAVLLLFVVCWLPFQISTFLDTLLRLGVLSGCWDEHAVDVITQISSYVAYSNSGLNPLVYVIVGKRFRKKSREVYRVLCQKGGCMGEPVQMENSMGTLRTSISVERQIHKLQDWAGKKQ
What is the function of this protein?
Receptor for bradykinin.  It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).
What are the official names of this protein?
B2 bradykinin receptor, B2R, BK-2 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Bradykinin receptor subfamily. BDKRB2 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MENG_BACC1
Sequence: MQQSKEERVHDVFEKISDKYDVMNSVISFQRHKAWRKETMRIMDVKPGSKALDVCCGTADWTIALAEAVGEQGKVVGLDFSENMLSVGKQKVEALQLKQVELLHGNAMELPFEDNTFDYVTIGFGLRNVPDYMHVLKEMTRVVKPGGKVICLETSQPTMIGFRQGYILYFKYIMPLFGKLFAKSYKEYSWLQESASTFPGMKELANMFEKAGLERVQVKPFTFGVAAMHLGMKPESK
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: WHIA_BACC4
Sequence: MSFASETKKELTNLEMKECCEKAELSALLRMNGSLSFSNRRLSIDIQTENAAIARRIYTLLKKGYDVTVELLVRKKMRLKKNNVYIVRLVEKSREILADLHIVRDDFSFIRNISQELIEKKCCKRSYLRGAFLAGGSVNNPETSSYHLEIFSLYKEHNDAICELMNGFDLNSKTLERRKGYITYLKEAEKITEFLNIIGAHNALLRFEDIRIVRDMRNSVNRLVNCETANLNKTIGAALRQIENIRYIDETVGLDILPDKLQEIAQLRRDYQDVTLKELGEMVSGGKISKSGINHRLRKIDEIAEKLRAGETLVKK
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: MTD1_DESNO
Sequence: MNIIDLFAGCGGFSHGFKMAGYNSILAIEKDLWASQTYSFNNPNVSVITEDITTLDPGDLKISVSDVDGIIGGPPCQGFSLSGNRDQKDPRNSLFVDFVRFVKFFSPKFFVMENVLGILSMKTKSRQYVKDIIAEEFSNVGYKVCVIILNACDYGVPQSRQRVFFIGLKSDRPLNQQILTPPSKVIESEYTSLEEAISDLPVIEAGEGGEVQDYPVAPRNKYQENMRKGSTCVYNHVAMRHTQRLVDRFAAIKFGQSVKHVSEEHSQRKRGDANSISGKVFSQNNMRPYPYKPCPTVAASFQSNFIHPFYNRNFTAREGARIQSFPDTYIFQGKRTTMSWEKHLSQYQQIGNAVPPLLAQALAERISWYFENINLINDSNVSIKRMVQRSFMSQLNLENNVNVRQDDNYDKVHSF
What is the function of this protein?
A methylase that recognizes the double-stranded sequence 5'-CTNAG-3', methylates C-1 on both strands, and protects the DNA from cleavage by the DdeI endonuclease.
What are the official names of this protein?
Type II methyltransferase M.DdeI, M.DdeI, Cytosine-specific methyltransferase DdeI, Modification methylase DdeI.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Protein: COX18_HUMAN
Sequence: MLCRLGGRWLRPLPALQLWARDLPLAPVPTSGAKRPTLPVWAVAPVSAVHANGWYEALAASSPVRVAEEVLLGVHAATGLPWWGSILLSTVALRGAVTLPLAAYQHYILAKVENLQPEIKTIARHLNQEVAVRANQLGWSKRDARLTYLKNMRRLISELYVRDNCHPFKATVLVWIQLPMWIFMSFALRNLSTGAAHSEGFSVQEQLATGGILWFPDLTAPDSTWILPISVGVINLLIVEICALQKIGMSRFQTYITYFVRAMSVLMIPIAATVPSSIVLYWLCSSFVGLSQNLLLRSPGFRQLCRIPSTKSDSETPYKDIFAAFNTKFISRK
What is the function of this protein?
Mitochondrial membrane insertase required for the translocation of the C-terminus of cytochrome c oxidase subunit II (MT-CO2/COX2) across the mitochondrial inner membrane.  Plays a role in MT-CO2/COX2 maturation following the COX20-mediated stabilization of newly synthesized MT-CO2/COX2 protein and before the action of the metallochaperones SCO1/2.  Essential for the assembly and stability of the mitochondrial respiratory chain complex IV (also known as cytochrome c oxidase).
What are the official names of this protein?
Cytochrome c oxidase assembly protein COX18, mitochondrial, COX18Hs, Cytochrome c oxidase assembly protein 18.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family.