PharMolix/UniProtQA huggingface dataset:
Protein: CELF1_CHICK
Sequence: MNGTLDHPDQPDLDAIKMFVGQVPRSWCEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKILPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMHQAQTMEGCSSPIVVKFADTQKDKEQKRIAQQLQQQMQQISAASVWGNLAGLNTLGPQYLALYLQLLQQTAAASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSGTAALTSSSSPLSVLTSSAGSSPSSSGSSSVNPMASLGALQTLAGATAGLNVSSLAGMAALNGGLGSGGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQSLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY
What is the function of this protein?
RNA-binding protein that may be involved in pre-mRNA alternative splicing, mRNA translation activation and stability.
What are the official names of this protein?
CUGBP Elav-like family member 1, CELF-1, Bruno-like protein 2, CUG triplet repeat RNA-binding protein 1, CUG-BP1, CUG-BP- and ETR-3-like factor 1, RNA-binding protein BRUNOL-2.
What is the protein family that this protein belongs to?
Belongs to the CELF/BRUNOL family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: SYH_ANASK
Sequence: MKINGVKGMNDVLPADVARWHEMESVAREVFALYGYREVRTPAVEHAALFARGVGEATDIVNKEMYVFEDKGEELLALRPEGTAGTVRAFIEHGAFVEGPQKWFYMGPMFRRERPQKGRYRQFHQIGCEAFGVAEPYLDAEQIALLADYFARLGVTAELKLNSVGDAQCRPAYLADLKAYLVANQGALCADCKDRIERNPLRVLDCKVESCQPVLEQAPQLLERLCEPCRTHFDQVKAGLDALGVAYRVEPRLVRGLDYYVRTAYEFTSDALGSQSAVAGGGRYDRLVETLGGPPTPGIGFALGEERLSMILEKVGRAMPERRPAVFFVSADATGALEALRLAAGLRRAGIACELDPRGGKLKAQFKQAERVGARWAVVLGGNEVATGQAKLKDLQTREETPVALSELAARVSG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_PSEPK
Sequence: MAVQQNKKSRSARDMRRSHDALSENALSVEKTTGEVHLRHHVSPEGVYRGRKVVDKGADE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: RNP1_AERPE
Sequence: MKGRRPSHRRQLIPPLLTGLRVKVLAHSDPSLEGLEGWVVVEEARSLRILTLEGRVSTVLKDLAVIEVEAPGGEYIRISGRVLIGNPLDRVKEYRWRVSRRCRSSSRLKT
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 1, RNase P component 1, Rpp29.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEXR_PSEPK
Sequence: MRNLLEQIQGRLDELNKAERKVAEVILLNPQQATRFSIAALAQAAKVSEPTVNRFCRSFGVSGYPELKLQLAQSLASGAAYVSRAVEADDDPAAYTQKIFASAIASLDSACQQLDPQQVSRAVDMMIQARQIHFFGLGASAPVALDAQHKFFRFNLAVSAHADVLMQRMLASVAHTGDLFVIISYTGRTRELVEVARLARENGASVLGLTAAGSPLANACSLSLHIPLPEDTDIYMPMTSRIIQLTVLDVLATGMTLRRGVDFQPHLRKIKESLNASRYPIEDDDLN
What is the function of this protein?
Involved in regulation of glucose metabolism.  Transcriptional repressor of the gap-1 gene and of the edd-glk-gltR-2 and zwf-pgl-eda operons.  Acts by binding directly to an inverted pseudopalindromic sequence in the promoter region.
What are the official names of this protein?
HTH-type transcriptional regulator HexR.
Protein: SPEE_PYRCJ
Sequence: MRKVPGPITLIEPLSGNTSLLIKINAIHSVKKSPYQEIIIADTEDYGRVLILDDYIQSSYVDEQYYHESLVHPAMATHPNPRDVLILGGGEGATLREALKHGTVKRAVMVDIDRDVVELSRAYLPQMHQGAFDDPRAKVVIQDGFVYVEEAIKAGDKYDVIIMDLTDPYSSDIAKQLYTREFFAKIRRILNDDGVVVTQAGNSFYFPAEYDMVLEGVKANFPIVAEYEVWIPSFGYAVNFILGSLRYDPHALTPSEVDERLRARGVKTAFYTGRVHLALMNMPIHRKLR
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMU1_RAT
Sequence: MSIEIESSDVIRLIMQYLKENSLHRALATFTEETTVSLNTVDSIESFVADINSGHWDTVLQAIQSLKLPDKTLIDLYEQVVLELIELRELGAARSLLRQTDPMIMLKQTQPERYIHLENLLARSYFDPREAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQALKWQQHQGLLPPGMTIDLFRGKAAVKDVEEEKFPTQLSRHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHEKDVIGIAHHPHQNLIATYSEDGLLKLWKP
What is the function of this protein?
Involved in pre-mRNA splicing as a component of the spliceosome (By similarity).  Regulates alternative splicing of the HSPG2 pre-mRNA (By similarity).  Required for normal accumulation of IK (By similarity).  Required for normal mitotic spindle assembly and normal progress through mitosis (By similarity).
What are the official names of this protein?
WD40 repeat-containing protein SMU1, Brain-enriched WD repeat-containing protein, Smu-1 suppressor of mec-8 and unc-52 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SMU1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus speckle. Note=Colocalizes with SRSF1 in nuclear speckles.
Protein: PGKB_TRYBB
Sequence: MSLKERKSINECDLKGKKVLIRVDFNVPLDDGNITNDYRIRSALPAVQKVLTEGGSCVLMSHLGRPKGVSMAEGKELGSAGGIPGFEQKATLKPVAKALSELLSRPVTFAPDCLNAADVVSKMSPGDVVLLENVRFYKEEGSKKSTEEREAMAKILSSYGDVYISDAFGTAHRDSATMTGIPKILGNGAAGYLMEKEISYFAKVLGNPPRPLVAIVGGAKVSDKIQLLDNMLQRIDYLLIGGAMAYTFLKAQGYSIGISMCEESKLEFARSLLKKAEDRKVQIILPIDHVCHTEFKAVDSPLITEDQNIPEGHMALDIGPKTIEKYVQTIGKCKSAIWNGPMGVFEMVPYSKGTFAIAKAMGRGTHEHGLMSIIGGGDSASAAELSGEAKRMSHVSTGGGASLELLEGKTLPGVTVLDDKE
What are the official names of this protein?
Phosphoglycerate kinase, cytosolic, PGK B allele 2, Phosphoglycerate kinase B.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_LEPBP
Sequence: MSKKVKVAVTGAAGQIGYALLFRIASGQMFGPDTAVELQLLELEQAIPAAKGVIMELDDCAFPLLEKVSVSSNIDEAFRDINWALLVGSVPRKAGMERGDLLKINGGIFTTQGKAIEKNAASDVRVLVVGNPCNTNALIAMNNAKGVPSDRWFAMTGLDENRAKTQLAQKAGVLVKDVSNVAIWGNHSATQYPDFFNAKVNGKPATDVISDHDWLKGDFISTVQKRGAAIIAARGASSAASAANAVVDTVHNIVTPTKPGDWFSAACHSNGEYGVDKGLIFGYPLKSDGKKVEIVTGLEINAFGKEKFDITHNELKEERNEVKDMLG
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: GATB_SULTO
Sequence: MVKIGLEVHVHLTSLKTKLFCSCPSDYTGKDPNTNVCPICLGLPGAIPVLNENAVKAAIMVALAINAEIANSLIMVRKHYFYPDMAKNYQISQYDGPGSIAISKGGYLKLREGKTVRIRRINIEEDPAKIIYPTGSMLTSKYTLLDYNRSGMGLLEIVTEPDMTEPKEAREFLEKLRSILEHLGVCNCDLEGAMRADANVSVEGGERVEIKNIGSPREVEEALKYEIARQKAAIAQGLPVKRETRHWDSERKVTVPTRTKETEEDYRYFPDPDLPPYPITQDLIEEIRKTLPELPDLRIKRLVTQYGISDYDATVLVMDKALADLFEETAKHYSNYKKLVNLLINDYLRWLNDKNLRPSQSKAGSQHLVELLKLLDDGVITIKIAKEILPEIVLEGKMPSSIIKERGLVAIKDEDYLINVIKEVINEEPDAAEKAKNDPKVINYLVGKVMKKTGKRADPQLTNELIKKILGIK
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: CAPP_GLOVI
Sequence: MNWDTPIDLAAAGSPSALSHQSLRDNIELVEQLLRQVAAQEGGGDLVELLDRLWASHQDRTGEGLALIRELSLEKSVLAIRAFSIYFQLINIVEQHHERKRLRLQASFSADTAQPGSFCWLFDEMKSLGVSTPEIERVLQQLDVRLVFTAHPTEIVRRTIRTKHRRIVHLLDDLDNALSEWQQQQVHTTMLEEIRIWWRTDELHQVRPTVLDEVAHTVHYFEEVLFEAMPRVRSELVRCLDMFHPSLTRSLGTFCRFGSWVGSDRDGNPSVNALVTWKTACHQRSRVLAKYIKSVERLRDLLSLAEGNPPQDLLLALEQDQRDLGEVYERYSVVYLQEPYRLKLSYILERLEHTRERNAWLEVHGPQRLSQPDEPGWLHYYRHAHELLAELHLLRQCLRTTGIGCRPLETLIDQVEVFGFHLAGLDVRQDSTRHEDTLTEVSAKLRLTATPYAELDEQARLEWLVRELQTLRPLIPAELPFSARTEETIQTFRMIRRLQKEFGSEICHTYIISMSKQASDLLEVLLLAEEAGLFDPATGTGTLMVVPLFETVEDLRNAPHVLEQLFSLPLYRCYLTCHQNLQEVMLGYSDSNKDSGFLSSSWEIFLAQQHIQQVARRHGVQLRIFHGRGGTVGRGGGPSYQAILAQPDGTVSGRIKITEQGEVLASKYSLFELAAFNIETVTAAVIQASVLPTSPPGSRNWELRLQELSDVARRTYRQLVYEQEGFIDFFCHVTPIDEISQLQISSRPSRREGRRDLASLRAIPWVFSWTQSRFLLQAWYGLGTALDGFIRCNRERNLAELRSMYRQWPFFRTLISKVEMTLAKVDLQVAANYVQELLPKEHEHTGECIFALIAAELERTRECVLAITEHRQLLEDNPPLQRSIALRNATIAPLGYLQATLLKYLRYENRQPRSYSRNELLRGALLTINGIAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: TIM21_GIBZE
Sequence: MNPTTNLLVTRSTAFRGVPTTLRPFLASRYYATQQGLGATPRGPKRRAVTPFNDNGHVPWKQLSVAEKAARATQQSFNFGMILVGLMLTGGVGYFLWTDVFSPDSKISNFNRAVDKIRSDPRIIDVMGDSKKIAAHGDETFNKWRRARPVASSETTDARGDQHIMMHFYVEGPKNNGVARLHMIKYRGHSDFEYKYLFVDVKDHERIYLEHEDSSSKNGKKFSLFGVKW
What is the function of this protein?
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.  Required to keep the TOM and the TIM23 complexes in close contact.  At some point, it is released from the TOM23 complex to allow protein translocation into the mitochondrial matrix (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM21.
What is the protein family that this protein belongs to?
Belongs to the TIM21 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: FTSH_ECOLI
Sequence: MAKNLILWLVIAVVLMSVFQSFGPSESNGRKVDYSTFLQEVNNDQVREARINGREINVTKKDSNRYTTYIPVQDPKLLDNLLTKNVKVVGEPPEEPSLLASIFISWFPMLLLIGVWIFFMRQMQGGGGKGAMSFGKSKARMLTEDQIKTTFADVAGCDEAKEEVAELVEYLREPSRFQKLGGKIPKGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISGSDFVEMFVGVGASRVRDMFEQAKKAAPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLNQMLVEMDGFEGNEGIIVIAATNRPDVLDPALLRPGRFDRQVVVGLPDVRGREQILKVHMRRVPLAPDIDAAIIARGTPGFSGADLANLVNEAALFAARGNKRVVSMVEFEKAKDKIMMGAERRSMVMTEAQKESTAYHEAGHAIIGRLVPEHDPVHKVTIIPRGRALGVTFFLPEGDAISASRQKLESQISTLYGGRLAEEIIYGPEHVSTGASNDIKVATNLARNMVTQWGFSEKLGPLLYAEEEGEVFLGRSVAKAKHMSDETARIIDQEVKALIERNYNRARQLLTDNMDILHAMKDALMKYETIDAPQIDDLMARRDVRPPAGWEEPGASNNSGDNGSPKAPRPVDEPRTPNPGNTMSEQLGDK
What is the function of this protein?
(Microbial infection) Probably transports the toxic C-terminal region of CdiA from E. coli strain 536, E. cloacae strain ATCC 13047 and of Y. pestis strain A across the inner membrane to the cytoplasm, where CdiA has a toxic effect.  Toxin transport is strain-specific, mutations in this gene do not confer resistance to several other tested CdiA toxins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH, Cell division protease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y700_NEIMA
Sequence: MTFLQRLQGLADNKICAFAWFVVRRFDEERVPQAAASMTFTTLLALVPVLTVMVAVASIFPVFDRWSDSFVSFVNQTIVPQGADMVFDYINAFREQANRLTAIGSVMLVVTSLMLIRTIDNTFNRIWRVNSQRPWMMQFLVYWALLTFGPLSLGVGISFMVGSVQDAALASGAPQWSGALRTAATLTFMTLLLWGLYRFVPNRFVPARQAFVGALATAFCLETARSLFTWYMGNFDGYRSIYGAFAAVPFFLLWLNLLWTLVLGGAVLTSSLSYWQGEAFRRGFDSRGRFDDVLKILLLLDAAQKEGKALPVQEFRRHINMGYDELGELLEKLARHGYIYSGRQGWVLKTGADSIELNELFKLFVYRPLPVERDHVNQAVDAVMMPCLQTLNMTLAEFDAQAKKQQQS
What are the official names of this protein?
UPF0761 membrane protein NMA0700.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GUAA_LACGA
Sequence: MAKTNLNDFDKIIVLDFGSQYNQLITRRIRDFGIYSELLPHDLSIEKIKKMAPKGIIFSGGPNSVYDEGALKVDPEIFKLGIPILGICYGMQLMSYDLGGKVEKADNSEYGRADIEVTDPNAVLFEGLPKEQYVWMSHGDLVTKAPEGFKVTAKSKNCPISAIANDEKKFYGIQFHAEVRNSEYGLDILKNFAFNVCDAKANWTMDDFIEMQVDEIREKVGDKKVILGLSGGVDSSVTATLLHKAIGDQLTAIFVDHGMLRKDEGDQVMQALNKDLGVNIIRVNAQKRFLDKLKGVTDPEQKRKIIGKEFIEVFNEEAKKLKDVDFLAQGTLYTDVIESGTNTAQTIKSHHNVGGLPEDMHFELIEPLRKLFKDEVRELGEKLGIPHDLVWRQPFPGPGLAIRVLGEVTEDKLKIVRESDAILRDEIKKAGLQEDIWQYFTVLPGIRSVGVMGDGRTYDYTIGIRAVTSIDGMTADFAKLPWDVLSKISTRIVDECDHINRVVYDITSKPPSTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: COAD_GEOTN
Sequence: MASIAVCPGSFDPVTYGHLDIIKRGAKVFDQVYVAVLNNSSKKPLFTVEERMELLREVTRTLDNVHVESFHGLLVDYARSKKANAILRGLRAVSDFEYEMQITSMNRVLDENIETFFMMTNSQYAFLSSSIVKEVAKYNGDISELVPPVVEAALKRKFASAVAD
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_CUTAK
Sequence: MSNIIDEIDKASMRDDIPEFRPGDSVKVHVKVVEGSRTRVQVFSGIVISRTGGGVQESFTVRKLSFGTGVERTFPLHSPIIDKIEVDRHGAVRRAKLYYLRGRRGKAAKIKERGSAR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: MNMG_ACTP2
Sequence: MIYHEIYDVIVVGGGHAGTEAALAPARMGLKTLLLTHNVDTLGQMSCNPAIGGIGKGHLVKEIDAMGGLMAIAIDQAGIQFRTLNSSKGPAVRATRAQADRVLYRQAVRTALENQPNLDIFQQEVVDILVENNRAVGAVTKMGLTFKARSVVLTAGTFLAGKIHIGLDNYAGGRAGDPAATMLADRLRDLNLRVDRLKTGTPPRLDARTINFDVLAKQHGDAELPVMSFMGSVDLHPRQIPCHITHTNEQTHDLIRNSLDRSPMYTGIIEGIGPRYCPSIEDKVMRFSDRNSHQIYLEPEGLSTIEVYPNGISTSLPFDVQMGIVNSMKGLEKTRIIKPGYAIEYDYFDPRDLKPTLETKAIEGLFFAGQINGTTGYEEAAAQGLLAGINAALQVQGKEAWFPTRDLAYTGVLVDDLCTLGTKEPYRVFTSRAEYRLLLREDNADIRLTPIAHELGLIDDARWARFNQKMENIERERERLKQIWIHPQSEHLAVVNELVNSPLTREASGEDLLRRPEVTYDKLTQVAAFAPALDDKQAAEQVEISIKYQGYIEHQQNEIERHKRHENTLIPAEFDYDKVESLSNEVRAKLMQHRPVSIGQASRISGITPAAISILLVNLKKQGMLKRGEL
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_SHEFN
Sequence: MYAVFQSGGKQHRVAEGHTVRLEKLEVATGETVEFDQVLLIADGETVHVGAPLVAGGKVVAEVVGHGRGEKVTIIKFRRRKHHDKKMGHRQWFTEVKITAISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RENI1_MOUSE
Sequence: MDRRRMPLWALLLLWSPCTFSLPTRTATFERIPLKKMPSVREILEERGVDMTRLSAEWGVFTKRPSLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR
What is the function of this protein?
Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
What are the official names of this protein?
Renin-1, Angiotensinogenase, Kidney renin.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted. Membrane. Note=Associated to membranes via binding to ATP6AP2.
Protein: WDR33_HUMAN
Sequence: MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDFAQQQAMQQLTFDGKRMRKAVNRKTIDYNPSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMNAVTTKFVRTSTNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWHVGVEKEVGGMEMAHEGMIWSLAWHPLGHILCSGSNDHTSKFWTRNRPGDKMRDRYNLNLLPGMSEDGVEYDDLEPNSLAVIPGMGIPEQLKLAMEQEQMGKDESNEIEMTIPGLDWGMEEVMQKDQKKVPQKKVPYAKPIPAQFQQAWMQNKVPIPAPNEVLNDRKEDIKLEEKKKTQAEIEQEMATLQYTNPQLLEQLKIERLAQKQVEQIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPPRRGASRGGGRGR
What is the function of this protein?
Essential for both cleavage and polyadenylation of pre-mRNA 3' ends.
What are the official names of this protein?
pre-mRNA 3' end processing protein WDR33, WD repeat-containing protein 33, WD repeat-containing protein of 146 kDa.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR33 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: A3AEM_PHYIN
Sequence: MRLAIMLSATAVAINFATSSAIDQTKVLVYGTPAHYIHDSAGRRLLRKNEENEETSEERAPNFNLANLNEEMFNVAALTERADAKKLAKQLMGNDKLADAAYMWWQHNRVTLDQIDTFLKLASRKTQGAKYNQIYNSYMMHLGLTGY
What is the function of this protein?
Multifunctional effector that can suppress host BAK1/SERK3-mediated immunity through at least two different pathways (PubMed:19794118, PubMed:20457921, PubMed:21348873, PubMed:26348328).  Manipulates plant immunity by targeting and stabilizing host E3 ligase CMPG1.  Preventing the normal 26S proteasome-dependent degradation of potato CMPG1, and thus potentially of its protein substrates in the host cell, further abolishes host cell death during the biotrophic phase of infection (PubMed:19794118, PubMed:20457921, PubMed:21348873).  Associates with and affects also the function of the dynamin-related protein 2 (DRP2), a plant GTPase involved in immune receptor-mediated endocytosis (PubMed:26348328).  The Avr3a(EM) form evades recognition by R3a, thus does not trigger R3a-mediated hypersensitivity and does not suppress INF1-induced cell death (PubMed:15894622, PubMed:16965554, PubMed:19245321).
What are the official names of this protein?
RxLR effector protein Avr3a, Avirulence protein 3a.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm.
Protein: PYRF_THEVB
Sequence: MFNSQAAVASKIIVALDVPNLEVAIATIHRLPQVQFWKVGLELFCASGPMILDVLKDQGKRIFLDLKLHDIPNTVAAAARAIAPYGVDFVTIHTATGLTGLKTAQAALGESATQLIGVTLLTSIGADTLQQELQIPLDPATYVECMANLAHQAGLAGIVCSPQEAARVKQRWGENFLRICPGIRPLGSATGDQARSLTPNAAFAAGASYLVIGRPILQAADPAAAFDDLCSSLV
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: NS3B_SARS
Sequence: MMPTTLFAGTHITMTTVYHITVSQIQLSLLKVTAFQHQNSKKTTKLVVILRIGTQVLKTMSLYMAISPKFTTSLSLHKLLQTLVLKMLHSSSLTSLLKTHRMCKYTQSTALQELLIQQWIQFMMSRRRLLACLCKHKKVSTNLCTHSFRKKQVR
What is the function of this protein?
Induces host cell G0/G1 arrest and apoptosis.
What are the official names of this protein?
ORF3b protein, Accessory protein 3b, Non-structural protein 3b, ns3b, Protein X2.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host mitochondrion.
Protein: YFH7_ASHGO
Sequence: MDYEDLKKRVWDLLAQNIESNYRVAVVVVGHPGSGKSTMAQRLKRDLNQEFQSHLKARRGGLRISAGIAAESLDETVPVASGALVEEARRGFFAHVEDPGFKPHKFYDGDGTAVIFGRGGLPNSVRIASEALDPASSVNIAEVVPMDGFHLSRAHLDHFADAAAAHKRRGAPWTFDSNNYLQLCKLLAATCKWKPAKRPKGETLMETICDTFAQCPVISYPGFDHAAKDPVRDQHVLTGFTRVLIFDGLYLLYDQENWAHIYHSLASTGAVLVVNVTASEETRETRVATRHFAAGLVGSIEEGVRKFRENDLLNAKLIEEHTLGGVPTLILSND
What is the function of this protein?
ATP-dependent kinase that could be involved in endoplasmic reticulum membrane assembly.
What are the official names of this protein?
ATP-dependent kinase YFH7.
What is the protein family that this protein belongs to?
Belongs to the YFH7 family.
Protein: DENN_SCHPO
Sequence: MESIADHFFLAGLSNGFVSVSNSQFRADRLDEDAISVSSSIIQNNTRKSPLKRVSITSESSFYKENTFAHHNTTGSNSVGPKKPFLDYHHSTSNTPTKKKKDSFDHASVTSLHRRSLSSNTSTPRKYHSRKPYSEPSVIDKEHLQNRVSIGTTHTQNDLYQSYVAYPDALPLFAATHPFERRYPPSLLHQFPSSKDIKNETPTIDRCDFPNYVPMFAFPNDITIKESDVRPVSTYHSFALTSDNNSHLYGICVVVWVAMPQSMQNDLEKECEVWRANNTTVEDREVAEKLLSSLETERSKLSSLLLKMQEKELEGSDSIDPILLEKIDVCEENIILYTELLRPMRYKLPRFVHGLTNNRTLWIPNAYGLLSKHSHLQSFCRDWLRIVCSSIQAEDLDFIPSSDLNSLKSLNLQSFVKNICCDVPLPPKGLLQLQVNVGPLNLYAFRSPVNEIPGWNDVDLYPLFRALSIPNILVLFEAALMEAKVIFLSENLGMLGYASQALLHLLYPLTWQGLYIPVLPRRLISCFEAPCSYIIGTLSYFFHMDDVPLDNIPLVVCDLDKNSVSTFGKIVRLSRSLRSKLQAHLKLAAPLHDKFYVPHSPPKYTMETYPNNVLSLSTVTCFPLREKFSIPALLSFRSSNFSKRPYVLSPILNGFLKLQDNPSSIYFAKQTDSRQSSASKLLYARLQAPEHARNFSSPPFTRPASPSSSKFRFSSSSFQSTIRRNSLTSPYSVPELRSSESNQNKAGSINTGSAVNLVSSKPGEQKVHIMYKEGHKLRRIYKMFPADSAGSICAVSGYALGDVHVQCDNCGLRVNLDFIKHISMPCVPACFNSQQILVTFLKFFIKILGSYRNYLRKPHMSRENFGISKGSGGLIGSFDFNKFTRQASKVHGSWISSLCSSQAFAEFIGDRCELDLNDPRVALFDQLLLCERNHGKPRLFGKATPFLRDKSLEIQRIEVAPIPASLKNDNALH
What are the official names of this protein?
DENN domain-containing protein C297.05.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PTH1R_HUMAN
Sequence: MGTARIAPGLALLLCCPVLSSAYALVDADDVMTKEEQIFLLHRAQAQCEKRLKEVLQRPASIMESDKGWTSASTSGKPRKDKASGKLYPESEEDKEAPTGSRYRGRPCLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLALDFKRKARSGSSSYSYGPMVSHTSVTNVGPRVGLGLPLSPRLLPTATTNGHPQLPGHAKPGTPALETLETTPPAMAAPKDDGFLNGSCSGLDEEASGPERPPALLQEEWETVM
What is the function of this protein?
Receptor for parathyroid hormone and for parathyroid hormone-related peptide.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
Parathyroid hormone/parathyroid hormone-related peptide receptor, PTH/PTHrP type I receptor, PTH/PTHr receptor, Parathyroid hormone 1 receptor, PTH1 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.