PharMolix/UniProtQA huggingface dataset:
Protein: CHP1_RAT
Sequence: MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFSEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLDKDDKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVLEKVDVEQKMSIRFLH
What is the function of this protein?
Calcium-binding protein involved in different processes such as regulation of vesicular trafficking, plasma membrane Na(+)/H(+) exchanger and gene transcription.  Involved in the constitutive exocytic membrane traffic.  Mediates the association between microtubules and membrane-bound organelles of the endoplasmic reticulum and Golgi apparatus and is also required for the targeting and fusion of transcytotic vesicles (TCV) with the plasma membrane.  Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity.  Affects the pH sensitivity of SLC9A1/NHE1 by increasing its sensitivity at acidic pH.  Required for the stabilization and localization of SLC9A1/NHE1 at the plasma membrane.  Inhibits serum- and GTPase-stimulated Na(+)/H(+) exchange.  Plays a role as an inhibitor of ribosomal RNA transcription by repressing the nucleolar UBF1 transcriptional activity.  May sequester UBF1 in the nucleoplasm and limit its translocation to the nucleolus.  Associates to the ribosomal gene promoter.  Acts as a negative regulator of the calcineurin/NFAT signaling pathway.  Inhibits NFAT nuclear translocation and transcriptional activity by suppressing the calcium-dependent calcineurin phosphatase activity.  Also negatively regulates the kinase activity of the apoptosis-induced kinase STK17B.  Inhibits both STK17B auto- and substrate-phosphorylations in a calcium-dependent manner.
What are the official names of this protein?
Calcineurin B homologous protein 1, Calcineurin B-like protein, Calcium-binding protein CHP, Calcium-binding protein p22, EF-hand calcium-binding domain-containing protein p22.
What is the protein family that this protein belongs to?
Belongs to the calcineurin regulatory subunit family. CHP subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Endomembrane system. Endoplasmic reticulum-Golgi intermediate compartment. Endoplasmic reticulum. Cell membrane. Membrane; Lipid-anchor. Note=Localizes in cytoplasmic compartments in dividing cells. Localizes in the nucleus in quiescent cells. Exported from the nucleus to the cytoplasm through a nuclear export signal (NES) and CRM1-dependent pathway. May shuttle between nucleus and cytoplasm. Localizes with the microtubule- organizing center (MTOC) and extends toward the periphery along microtubules. Associates with membranes of the early secretory pathway in a GAPDH-independent, N-myristoylation- and calcium-dependent manner. Colocalizes with the mitotic spindle microtubules. Colocalizes with GAPDH along microtubules. Colocalizes with SLC9A1 at the reticulum endoplasmic and plasma membrane. Colocalizes with STK17B at the plasma membrane.
Protein: RL13_METAC
Sequence: MLKMTVIDAKGLILGRLASSVAKQLLSGDEKVYIINAEQAIISGSRAATLREYRETRERGATEFGPYFPKRPDRILKRTIRGMLPYKRARGRDAMSRLKVYVGVPYELKGAETVTIPDADMRLLSSSRYVELGEVSQKMGSKF
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: TRXH5_ORYSJ
Sequence: MGCCGSSTVDAEEHLDYSGGNVTLVTDQKNWDNTMEEVAEHGKTVVLKFSAIWCTPCRNAAPLFAELSLKYPDIVFVSVDVDEMPELVTQYDVRATPTFIFMKNNEEIDKLVGGNHEDLQEKFEQLNRPKLYDDV
What is the function of this protein?
Probable thiol-disulfide oxidoreductase that may be involved in the redox regulation of a number of cytosolic enzymes.
What are the official names of this protein?
Thioredoxin H5, OsTrxh5, OsTrx20.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. Plant H-type subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRTO_STAA3
Sequence: MKTMKKYIKTAFFCSMYWLIVQLNIANLGTRIPDKYFRQKYIIFKSFNFEKHGKFWNKWFYVRKWKHKILDGHQLNQNIYDQRHLMTINTDEIEKMIIETKRAELIHWISILPVIIFNKGPRLVKYINIFYAMIANVPIIIVQRYNRPRLTQLLRILKRRGERHD
What is the function of this protein?
Catalyzes the acylation of glycosyl-4,4'-diaponeurosporenoate, i. e.  the esterification of glucose at the C6'' position with the carboxyl group of the C(15) fatty acid 12-methyltetradecanoic acid, to yield staphyloxanthin.  This is the last step in the biosynthesis of this orange pigment, present in most staphylococci strains (By similarity).
What are the official names of this protein?
Glycosyl-4,4'-diaponeurosporenoate acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase CrtO family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: HEMO_BOVIN
Sequence: MARALRVPVALWLLGLCWSLAKAHPLARAPELGHGVEGGNVAKPDPEVTERCSDGWGFDATTLDEHGNMLFLKGEFVWKGHAWARQLISERWKDAPSPVDAAFRYDRNSVLLIKGDKFWVYPPEKGEEYPKLLQEKFPGIPFPLDAAVECHRGECSHEGVFFFQGNHTWFWDFSTKTIKKRSWPAVGNCSSAIRWLNRYYCFRGNKFLRFDPVTGEVNSTYPRDVRDYFMSCPNRGHAHRNATQHMDKRCSPHLVLSALLSDNHSATYAFSENHYWRLDSSRDGWHSWRIEHLWPQGPSTVDAAFLWDKKLYLIQGTQVYIFLTRAGYTLVKDYPKQLEKEFGSPDGVCLHSVDAAFTCPGSSQLYIMAGQKLWRLDLNLGAQATWTELPWLHTKVDGALCTEKSLGPHSCSANGLGLYLVQGPNLYCYKDVEELSKTKDLPQAQRMNSLLGCAPHQHS
What is the function of this protein?
Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
What are the official names of this protein?
Hemopexin.
What is the protein family that this protein belongs to?
Belongs to the hemopexin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YDET_ECO57
Sequence: MSGYTVKPPTGDSNEQTQFIDYFNLFYSKRGQEQISISQQLGNYGATFFSASRQSYWNTSRSDQQISFGLNVPFGDITTSLNYSYSNNIWQNDRDHLLAFTLNVPFSHWMRTDSQSAFRNSNASYSMSNDLKGGMTNLSGVYGTLLPDNNLNYSVQVGNTHGGNTSSGTSGYSTLNYRGAYGNTNVGYSRSGDSSQIYYGMSGGIIAHADGITFGQPLGDTMVLVKAPGADNVKIENQTGIHTDWRGYAILPFATEYRENRVALNANSLADNVELDETVVTVIPTHGAIARATFNAQIGGKVLMTLKYGNKSVPFGAIVTHGENKNGSIVAENGQVYLTGLPQSGKLQVSWGNDKNSNCIVDYKLPEVSPGTLLNQQTAICR
What are the official names of this protein?
Fimbrial usher domain-containing protein YdeT.
Protein: PG036_VACCW
Sequence: MTSSAMDNNEPKVLEMVYDATILPEGSSMDPNIMDCINRHINMCIQRTYSSSIIAILDRFLMMNKDELNNTQCHIIKEFMTYEQMAIDHYGGYVNAILYQIRKRPNQHHTIDLFKRIKRTRYDTFKVDPVEFVKKVIGFVSILNKYKPVYSYVLYENVLYDEFKCFINYVETKYF
What is the function of this protein?
Plays a role in the inhibition of host innate immune response.  Within the host nucleus, inhibits activation of interferon-beta promoter by inhibiting IRF3 activation.
What are the official names of this protein?
Protein OPG036, Protein N2.
What is the protein family that this protein belongs to?
Belongs to the poxviridae OPG036 family.
Protein: EPL1_KLULA
Sequence: MPAPAVDSSRFRHRKISVKQRLRIYKSHEIKDLEQEDVSAISSQHQQRELMEIETGVEKNEEKEEHLYKILQSNQLRENKKDLFIPTPDASKTWDEFDRFYQGEFKCPTSYIQFSAQLEDCCGTLYNMDEEDEIFLADLNKSLADSVEPLTEDEFELIMANFESSIKDRQPFLSMDPESILSFADLKPTMLKNDVGDSGVKKELAKEIGMPEDEPFLTMFDNKRPLGKREKNMETLIELFGEKIHDHWKQRKISRHGCDIFPQLKSERNNDKDDNDPYVCFRRRELRQPRKTRRIDVQNSQKLRLLCQQLEYTKDLALTVAKRERAVLEVLENEKFVFQARAQLKTMKRKLGIDADNEDLYSAKKQKLVSSVRTIKQQQQLLLQKQLQIQQQQQQQLQQQQAAITSDSSVKRAKSSKSSKLHKEDSGLYADEKGSEPKKKGPKTGSNKNKEQSLSSAQEIGAQSPVANVSNVQQQQKQASSQVYVKLPNSKIPDIVLEDVGKLLHSKEKSTRKFVEDRMRKRKQEDGDIFFNLTDDPYNPVFNLSIPDNVSPQDAPFSSVAGSKFEVKTSYYSPNLQNYITGTANDIKVFNKEGEAVENNEYKKLEFFNPFDNEIHTHSREFPIAFRRRRGRFNMEYIDQRKTDHNINDMLLQFIDLDGIQKQELDNDVINVYDSKLDDLSRSYYHWKYDSNYNIYGSKFSDEPAKLNQISNDTQVVRFGTMLGSKAYEQLRDATIKYRQEQINKRKKLNSLQQQQMLQKGQQPINNAPHSQSSSPPSHQDTRKNPGSTPNQSSPPKKHVTPNAAA
What is the function of this protein?
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair.  Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M (By similarity).
What are the official names of this protein?
Enhancer of polycomb-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the enhancer of polycomb family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SFGH2_ECOL6
Sequence: MEMLEEHRCFEGWQQRWRHDSSTLNCPMTFSIFLPPPRDHTPPPVLYWLSGLTCNDENFTTKAGAQRVAAELGIVLVMPDTSPRGEQVANDDGYDLGQGAGFYLNATQPPWATHYRMYDYLRDELPALVQSQFNVSDRCAISGHSMGGHGALIMALKNPGKYTSVSAFAPIVNPCSVPWGIKAFSTYLGEDKNAWLEWDSCALMYASNAQDAIPTLIDQGDNDQFLADQLQPAVLAEAARQKAWPMTLRIQPGYDHSYYFIASFIEDHLRFHAQYLLK
What is the function of this protein?
Serine hydrolase involved in the detoxification of formaldehyde.  Hydrolyzes S-formylglutathione to glutathione and formate (By similarity).
What are the official names of this protein?
S-formylglutathione hydrolase YeiG, FGH.
What is the protein family that this protein belongs to?
Belongs to the esterase D family.
Protein: SYI_MARMS
Sequence: MSDYKPTLNLPDTDFPMRGDLAKREPAMLKRWQDMDLYQKVRDVTKGRKSFILHDGPPYANGSIHIGHAVNKILKDIIVKSKTVSGFDAPYIPGWDCHGLPIEHKVEQLIGKAGTKVSYKEFRAKCREYAYTQIEEQKKDFIRLGVMGDWENPYLTMNFQTEANIVRALGKIAENGHLVKGFKPVYWSVVGGSALAEAEVEYQDKTSLSLDVRYAPQDEAALLAKFSAVEGEGKVSVVIWTTTPWTLPASQAVSIHPEFNYALVEVDMGLGKERLILAEDMVASVMSRYGVTDFRIVGRTVGAELAGTVLNHPFLQRDIPVILGEHVTTEAGTGCVHTAPDHGVDDFNVGRENGIGTINLVQDNGVYSDAAGEFAGLHVYKVDDAVLEALNRNNALVFESKIFHSYPHCWRTKTPLIFRATPQWFISMTKEGLLDSAKHAVEGVKWVPSWGQNRMEGMLNNSPDWCVSRQRTWGVPIALFINKETQELHPETPRLIEEVAKRIEVEGIDAWFEMEAEELLGADAEKYSKVTDTLDVWFDSGVTHYSVIDQRDELSFPADLYLEGSDQHRGWFQSSLKTSIAIRGVPPYKQVLTHGFTVDGDGRKMSKSLGNVLSPQKVMDTLGADIIRLWVAATDYTTEMTVSDEILKRVADSYRRIRNTARFMMANLNGFNPATDMVPAKDMIALDRWIVDRAALLQKELNTAYNEYQFHTVNQKIQNFCSVDLGGFYLDVIKDRQYTTQKDSLARRSAQTALYHVIEAFSRWIAPILSFTADEIWQTLPGERGESVFLETWYEGLEELTGDEAMGREFWKQVLEAKVATNKVLEAARSEGKMKASLSADITLYCDDALQTTLNRLGEELRFVLIASDVKVLPLSQAGEDAVATDLDGLKVHVELSKYTKCVRCWHHREEVGKRDAHPELCDRCISNLPDGEGEQRLYA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TEKT1_MOUSE
Sequence: MAKLLQSPPRFLPEEWYIANKSQYHRAEAQRSQSERLVAESQRLVEEIEKTTRKSQSDVNKKLEQRLEEVRFWKKELDDKLEQLVNQTDDLLTYKTRLERSLESYKEPLHITEKCLEYREKRVGIDLVHDVVEQELQKEADIIHGVMNLLIRTLEESTEQIRLNRSAKYNLEKDLRDKFTAITIDDVCFSLNNNSPNINFSEKVVRIEPNSVSLEDWLDFSNANVEKADKQLNNSTALKTLVDQILSQTANDLRRQCEVVDEAFINGLKETKDARNKLADHLAKVMEEIASQEKNIMALENAITQQEGPAKVAHTRLETRTHRPNVELCRDIAQYRLIKEIQEINHNVARLKETLAQAQTQLKALYRRQLALQEEIQVKENTIYIDQVLCMEMRKSIPPRDGDDHGAWEGGIRAEAIC
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme.  Forms filamentous polymers in the walls of ciliary and flagellar microtubules.
What are the official names of this protein?
Tektin-1.
What is the protein family that this protein belongs to?
Belongs to the tektin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme.
Protein: CCME_PSEFS
Sequence: MNPLRRKRLLIILAILVGVGIAVGLALSALQQNINLFYTPTQIANGEAPIDTRIRAGGMVEKGSLKRSGDSLDVTFVVTDFNKAVTITYRGILPDLFREGQGIVALGKLNADGVVVADEVLAKHDEKYMPPEVTKALKDSGQSAPTPAKEG
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: ATPE_SHESM
Sequence: MAAMTVQLDIVSAESSIFSGRVASLQVTGSEGELGIMHGHAPLLSYIKPGMARIVKQDGSEEVFYLSGGLLEVQPSSVSVLADVVMRAKDIDEQAALEAKRRAEAHMATAGADFNYDAAMVELAKAMAQLRVVETIKKNIAR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GGT2_HUMAN
Sequence: MKKKLVVLGLLAVVLVLVIVGLCLWLPSASKEPDNHVYTRAAMAADAKQCLEIGRDTLRDGGSAVDAAIAALLCVGLMNAHSMGIGVGLFLTIYNSTTGKAEVINAREVAPRLAFASMFNSSEQSQKGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAVLENKRTVIEQQPVLWYVFCRDRKVLREGERLTLPRLADTYEMLAIEGAQAFYNGSLMAQIVKDIQAAGGIVTAEDLNNYRAELIEHPLNISLGDAVLYMPSARLSGPVLALILNILKGYNFSRESVETPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLRSQISDHTTHPISYYKPEFYTPDDGGTAHLSVVAEDGSAVSATSTINLYFGSKVCSPVSGILFNNEWTTSALPAFTNEFGAPPSPANFIQPGKQPLLSMCLTIMVGQDGQVRMVVGAAGGTQITTDTALAIIYNLWFGYDVKRAVEEPRLHNKLLPNVTTVERNIDQAVTAALETRHHHTQIASTFIAVVQAIVRTAGGWAAALDSRKGGEPAGY
What is the function of this protein?
Lacks catalytic activity due to its inability to undergo the autocatalytic cleavage needed to produce a mature, enzymatically active heterodimer.
What are the official names of this protein?
Inactive glutathione hydrolase 2, Gamma-glutamyltransferase 2 pseudogene, Inactive gamma-glutamyltranspeptidase 2, GGT 2.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Endoplasmic reticulum. Note=Co-localizes with calnexin in the endoplasmic reticulum.
Protein: A3LT2_MOUSE
Sequence: MALGTELGVSWPGSHGSCREQEGQRQRGPGKPTWGLSRAKKRLLWRFFLSAFGFLGLYHYRFIIIRLIEGSIPMGTCPTAIMPLPRDNFTGVLHHWARPEVLTCTSWGAPIIWDGTFDPHVAQQEARRRNLTIGLTVFAVGRYLEKYLEHFLVSAEQHFMVGQNVVYYVFTDRPEAVPYVALGQGRLLRAKPVQRERRWQDVSMARMPTLHEALGGQLGQEADFVFCLDVDQYFTGNFGPEVLADLVAQLHAWHYRWPRWLLPYERDKRSAAALSLSEGDFYYHAAVFGGSVAALLKLTAHCATGQQLDHKRGIEALWHDESHLNKFFWLNKPTKLLSPEFCWAEEIIWRREIHHPRLLWAPKEYTLVRN
What is the function of this protein?
Synthesizes the galactose-alpha(1,3)-galactose group on the glycosphingolipid isoglobotrihexosylceramide or isogloboside 3 (iGb3) by catalyzing the transfer of galactose from UDP-Galactose to its acceptor molecule Gal-beta-1,4-Glc-ceramide.  Can also catalyze the addition of galactose to iGb3 itself to form polygalactose structures.  Synthesis of iGb3 is the initial step in the formation of the isoglobo-series glycolipid pathway and is the precursor to isogloboside 4 (iGb4) and isoForssman glycolipids.  Can glycosylate only lipids and not proteins and is solely responsible for initiating the synthesis of isoglobo-series glycosphingolipids.
What are the official names of this protein?
Alpha-1,3-galactosyltransferase 2, Isoglobotriaosylceramide synthase, iGb3 synthase, iGb3S.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 6 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Also found in numerous large vesicles throughout the cytoplasm of the soma.
Protein: GREA_RHILV
Sequence: MVEKVPMTPGGFVKLQEELRWRQQEERPRIIEAIAEARAHGDLSENAEYHAAKEAQSHNEGRISELEDLTARAEVIDLTKMSGDKIKFGAKVKLIDEDTEEEKTYQIVGDQEADVKAGRISISSPIARALIGKEVGDSIEVNAPGGSKAYEILQVSWG
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: LAMB2_KLEP7
Sequence: MMITLRKLPLAVAVAAGVMSAQALAVDFHGYARSGIGWTGSGGEQQCFKATGAQSKYRLGNECETYAELKLGQELWKEGDKSFYFDTNVAYSVNQEDDWESTSPAFREANIQGKNLIDWLPGSTLWAGKRFYQRHDVHMIDFYYWDISGPGAGLENVDLGFGKLSLAATRNSESGGSYTFSSDDTKKYAAKTANDVFDIRLAGLETNPGGVLELGVDYGRANPQDDYRLEDGASKDGWMWTGEHTQSIWGGFNKFVVQYATDAMTSWNSGHSQGTSIDNNGSMIRVLDHGAMDFNDDWGLMYVAMYQDVDLDSKNGSTWYTVGVRPMYKWTPIMSTQLEIGYDNVKSQRTSENNNQYKITLAQQWQAGNSVWSRPAIRIFATYAKWDENWGYSNTSGLQTKDSSGSGAFTSSRGDDSEVTFGAQMEVWW
What is the function of this protein?
Involved in the transport of maltose and maltodextrins.
What are the official names of this protein?
Maltoporin 2, Maltose-inducible porin 2.
What is the protein family that this protein belongs to?
Belongs to the porin LamB (TC 1.B.3) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: COQ5_HUMAN
Sequence: MAAPGSCALWSYCGRGWSRAMRGCQLLGLRSSWPGDLLSARLLSQEKRAAETHFGFETVSEEEKGGKVYQVFESVAKKYDVMNDMMSLGIHRVWKDLLLWKMHPLPGTQLLDVAGGTGDIAFRFLNYVQSQHQRKQKRQLRAQQNLSWEEIAKEYQNEEDSLGGSRVVVCDINKEMLKVGKQKALAQGYRAGLAWVLGDAEELPFDDDKFDIYTIAFGIRNVTHIDQALQEAHRVLKPGGRFLCLEFSQVNNPLISRLYDLYSFQVIPVLGEVIAGDWKSYQYLVESIRRFPSQEEFKDMIEDAGFHKVTYESLTSGIVAIHSGFKL
What is the function of this protein?
Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial, Ubiquinone biosynthesis methyltransferase COQ5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: HEMA_CVBLY
Sequence: MFLLPRFVLVSCIIGSLGFDNPPTNVVSHLNGDWFLFGDSRSDCNHVVNTNPRNYSYMDLNPALCDSGKISSKAGNSIFRSFHFTDFYNYTGEGQQIIFYEGVNFTPYHAFKCTTSGSNDIWMQNKGLFYTQVYKNMAVYRSLTFVNVPYVYNGSAQSTALCKSGSLVLNNPAYIAREANFGDYYYKVEADFYLSGCDEYIVPLCIFNGKFLSNTKYYDDSQYYFNKDTGVIYGLNSTETITTGFDFNCHYLVLPSGNYLAISNELLLTVPTKAICLNKRKDFTPVQVVDSRWNNARQSDNMTAVACQPPYCYFRNSTTNYVGVYDINHGDAGFTSILSGLLYDSPCFSQQGVFRYDNVSSVWPLYPYGRCPTAADINNPDVPICVYDPLPLILLGILLGVAVIIIVVLLLYFMVDNGTRLHDA
What is the function of this protein?
Structural protein that makes short spikes at the surface of the virus.  Contains receptor binding and receptor-destroying activities.  Mediates de-O-acetylation of N-acetyl-4-O-acetylneuraminic acid, which is probably the receptor determinant recognized by the virus on the surface of erythrocytes and susceptible cells.  This receptor-destroying activity is important for virus release as it probably helps preventing self-aggregation and ensures the efficient spread of the progeny virus from cell to cell.  May serve as a secondary viral attachment protein for initiating infection, the spike protein being the major one.  May become a target for both the humoral and the cellular branches of the immune system.
What are the official names of this protein?
Hemagglutinin-esterase, HE protein, E3 glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the influenza type C/coronaviruses hemagglutinin-esterase family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Note=In infected cells becomes incorporated into the envelope of virions during virus assembly at the endoplasmic reticulum and cis Golgi. However, some may escape incorporation into virions and subsequently migrate to the cell surface.
Protein: RSE1_ASHGO
Sequence: MNEKEELHLYHVSLQKQRNYVHSCIGHFVDYRHHHIRAQGGSVEGGKKGSKWRKQLQICMATQTQVELYDVEEGRLRRLFTRTVFGTITGLSSVVADGRSVLIVVGDSGKMSVLRFKYEGGRVRLEALFNEPLSRSGVRRLSPQAHVSVDPQGRCVLLSAMERNKVCYLMDVKQGELQVSSPLEANRPNYVTMQTAACDVAFDNPIFASLEIDLADGAKYLFFYMLDLGLNHMAKVADFELGDGSANFIMSVPDLEQYGINTKAGGPDDGDPDAIVPFVLMGFDNYVSLKDLRGRYDINVQIPTRKLSQKTIITAGTVQKLKRDFFMLLQSNHGDLYKVKILPDEKTASPVVTISYFDTIPQAQNLHIFKHGYMFANSEYGNSYLYQFENLDDEEESMLTSVMPGRRLIIEPRTVLKNLLVADKLALVNPILSSQLTERVPLTIATSTLGDVRLFTAGVNFMDIISSPLPAAPLDIWTVATNGSRFHKLLFIALQESTMILKIAAGTVEELELPHNPFVIAQDKTVLIAHMGGQSIIQVTENKMVHIIENRDESYESKLEWFPPAGICILKASSNSTQLILALSNNEVVYFEIGSNESLNELQDRIEVEERITALAIGNGNRSDYMIIASVDSTVKVYSLKVQDQANFLEVVSMQVLVSPASSLQLASSGGSLCLHIGLDSGVYVRSKLDRNTGELFDVRTKYLGTKPVEISLLLDMNPYINEEVDDEGEEEEEQDDEESLGGPHSRLVPCVVLHSGKTWISYELDSSLFIRPLLNDQSLKRVAQFTSNEIQRNGCCSISSAGFLVIGRIGTFRNNDCWFQESSLALPDSEDSVNGNELENDEKDPDALLEEKQKVNSSIGKLIIPDPDDIKLFYYCEYNEVENSCRVSLFKQGISYKHENSTEAFQLIPDCRPSTATIARFGLDMKHLVISTVNGVLKTFVIRITKAANNRRFELLALHDTVAGSTIHAMCPFHDKLLVPLANAVVLYGLGKKQLLKKSISYLPTSITKIVALDQWNGTRVAVGDIHESVTLLHFDERKNQFIPVADDVTKRHVTVVKFVDECTVIGGDRFGNIWLLRLPLEYDRLIKEGVDSYLLTLNTGIPSNIRECVFKWQLLNHFYINDIPMSFHLIASPQMADRASILYAGLQGTIGYLIPLITRREIEFFDLLEQAMRDADHLFYLDQENRLNDTSELNDGADEEGSVIDRRFPSVQKKRKIPEGAYSLVGRDAMMYRSYYNPVRHVTDGDLCEQFLELYPSEKNFLAARVDNRSVQEIERRINDMRTNCM
What is the function of this protein?
Involved in pre-mRNA splicing and cell cycle control.
What are the official names of this protein?
Pre-mRNA-splicing factor RSE1.
What is the protein family that this protein belongs to?
Belongs to the RSE1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPI_GALSU
Sequence: MLISSVKVGEHFYFTLGVFKLHAQVFIVSFFVILILILFSVLGTNKMSQTPRGLQNFLEYVLEFIQDITKSQIGEPHYRDWVPFIGTLFLFIFVSNWSGALIPWKMIILPEGELSAPTNDINTTAALALLTSLAYFYAGISKKGLRYFSRYIKPTPILLPINILEDFTKPLSLSFRLFGNILADELVVSVLTLLVPLIVPLPVMMLGLFASSIQALIFATLAAAYIGEAIEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PSD_CLOBL
Sequence: MIKYYNRKNKDYDIEKVAGEKYLNWTYSSPIGMNLLEVFIKKKIFSKIYGFYCDRRLSQKKINKFINDFQIDMSLSENQLSNFKCFNDFFTRKLKKEARPIKTDKNLLISPGDGKLLAYENLNLNSVTEVKGINYSFYELINNDSLAKEYNNGTCLVLRLCPTDYHRFHFIDNGICENTIKLNGFYYSVNPIALSKIPSVFCKNKREYSIFHSENFGDIIFMEVGATCVGSIIQTYKPNTKVLKGDEKGYFKFGGSTVILFFKKNTIKIDDDILSQSKLGYETSVIMGEPIGNKK
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.