PharMolix/UniProtQA huggingface dataset:
Protein: HAS1_SCHPO
Sequence: MAKSELKRKKHQSGNEEVKEKRQKPLKNDKKIAEELPQDEDDYEQEEENEDADQNTSVESESEELDNENEDERVQKSVNLNASSTSDIEKFSDLQLSENIQKAIKEMGFETMTEIQKRSIPPLLAGRDVLGAAKTGSGKTLAFLIPTIEMLYALKFKPRNGTGVIIISPTRELALQIFGVAKELLKYHHQTFGIVIGGANRRAEADKLVKGVNLLVATPGRLLDHLQNTKGFVFRNLRSLVIDEADRILEIGFEDEMRQIMKILPSENRQTLLFSATQTTKVEDLARISLKPGPLYVNVDSGKPTSTVEGLEQGYVVVDSDKRFLLLFSFLKRNLKKKVIVFMSSCASVKYMAELLNYIDLPVLDLHGKQKQQRRTNTFFEFCNAEKGILLCTNVAARGLDIPAVDWIVQYDPPDDPRDYIHRVGRTARGTKGTGKSLMFLAPSELGFLRYLKTAKVSLNEFEFPANKVANVQSQLEKLVSKNYYLQQSAKDGYRSYLQAYASYSLKSIFDINKLDLAKVAKSFGFAHPPNVNITIGASGRTDKKERRAGYNKKNHVDVYSKQRSSAISQDKERGWSR
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent RNA helicase has1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: GCSP_PROM1
Sequence: MSKAELKDFTFKSRHIGPTNEDEALMLQHLGYENSEEFISSVIPNEIFDSENNVVSIPDGCDQNKALKEINIISKKNVEHRSLIGLGYHSTVIPPVIQRNVLENPNWYTAYTPYQAEISQGRLEALFNFQTLISELTGLPISNASLLDEATAAAEAISLSLAVRKNKNANKFLVDQEILPQTFDVLKTRCEPLGISLEMFENNNFEIDKNIFGILIQLPGKNGRIWDPTKIINDAHKCNAIVTIAIDPLAQVLIKPMGEFGADIVVGSAQRFGVPIACGGPHAAFFATKEIYKRQIPGRIVGQSVDVEGNQALRLALQTREQHIRRDKATSNICTAQVLLAVLSSFYAVHHGPKGLKQIAENVVKYRSNFESILMNLEYPIEKYSAFDSVDVYCSEASEVIQLASEEGYNFRVLPIGSDFENAKGFGVTFDELTCDEEIYTLHQILAQVKGKKAHDLSNFLNENASLVDIPLREKSWLEQSVFNQYQSETDLMRYIHSLVSKDFSLVQGMIPLGSCTMKLNSAAELLPIEWREFSSIHPFAPHAQLAGFHEIINDLENWLSALTGFQGVSLQPNAGSQGEFAGLLVIRSWHQSLGEGHRNICLIPTSAHGTNPASAVMSGFKVVSVKCDEYGNVDLEDLKNKSKIHSKNLAALMVTYPSTHGVFEPNIREMCQVIHQEGGQVYLDGANLNAQVGICRPGSYGIDVCHLNLHKTFSIPHGGGGPGVGPIAVADHLVPYLPGHSIIKCGGEKAISAVSAAPFGSAGILPISWMYIRMMGSDGLRKASSIAILSANYLAKRLDPYYPVLFKDPNGLVAHECILDLRPLKSQLGIEVEDVAKRLMDYGFHAPTISWPVAGTLMVEPTESESLPELDRFCDAMIGIREEIEQIKLGKIDPINNPLKQSPHTLKRVTSDDWDRPYSRKEAAYPLPDQEKYKFWPSVSRINNAYGDRNLICSCPSVQDLEDINSV
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: CLN8_CANLF
Sequence: MTPMSDGGTSESIFDLDYTSWKIRSTLAVAGFVFYLGVFVVCHQLSSSLNATYRSLVAREKVFWNLAATRAVFGVQSTAAGLWALLVDPVLHADKARGQQNWCWFHIATATGFFFFENVAVHLSNVLFRTFDLFLAIHHLFAFLGFLGSVVNLGAGHYLAMSTLLLEASTPFTCISWMLLKAGWSESLFWKLNQWLMIHMFHCRMVLTYHMWWVCFWHWDGLVSSLYLPHLALFLVGLGLLTLVINPYWTHKKTQQLLNPVDWNFAQPAPRSSRPAGANGQVPQKKGQ
What is the function of this protein?
Could play a role in cell proliferation during neuronal differentiation and in protection against cell death.
What are the official names of this protein?
Protein CLN8.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Endoplasmic reticulum.
Protein: TET5C_DANRE
Sequence: MASASTSSSNESESQSVLTWEQVSRLNDVLTEAVPVHGRGNFPTLEVRLKDIVQMVRNRLELRGIMVKDVRLNGSTASHVLVQDIGWSYKDLDVIFRVDLPREEEFQLIKDVVLSTLLDFLPEGVNKEKITPMTLKEAYVQKLVKVYTDQDRWSLISLSNNNGRNVELKFVDSIRRQFEFSVDSFQIILDSVLSYYDLSENPMSQHFHPTVVGESMYGDFVEALGHLTNKTIATKRPEEIRGGGLLKYCNLLVREFKPTDPDEFKALERYMCSRFFIDFPDIVEQQRKLEAYLQSHFIGEERNKYNYLMILRRVVNESTVCLMGHERRQTLNLISLTAFRVLAEQNAIPDVSSVTCYYQPAPYVKDLNFNNYYVASCNQSIPTWLPCN
What is the function of this protein?
Catalyzes the transfer of one adenosine molecule from an ATP to an mRNA poly(A) tail bearing a 3'-OH terminal group and enhances mRNA stability and gene expression.
What are the official names of this protein?
Terminal nucleotidyltransferase 5C.
What is the protein family that this protein belongs to?
Belongs to the TENT family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: TBA2_PATVU
Sequence: MRECISVHIGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTVGKEIIDLVLDRIRKLADQCTGLQGFLIFHSFGGGTGSGFSSLLMERLSVDYGKKSKLEFAIYPAPQISTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKCDPRHGKYMSCCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEGEGEEEGGEEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha-2/alpha-4 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: EFG_BIFA0
Sequence: MALDVLTNLNQVRNIGIMAHIDAGKTTTTERILFYTGKNYKIGETHEGASTMDFMAQEKERGITIQSAATTCFWNRQTHDPDEKFQINIIDTPGHVDFTAEVERSLRVLDGAVAVFDGKEGVEPQSETVWRQADKYGVPRICFINKMDKLGADFYYSVSTIKEKLGATPLVVQLPIGAENDFSGVVDLIRMKAYVWNDIKDDQGAHYDTVEIPDDLKERAEQYRSELLDQVAETDEELLEKYLENGDLSEQEIRGAIRQLTIAREAYPVLCGSAFKDKGVQPMLDAVVDYLPSPEDVPSIVGFDPSDESVEIDRKPTMDDPFSALVFKISTHPFYGKLVFVRVYSGSVKPGDNVLDSTKGKKERVGKIFQMHADKENPVDAAEAGNIYTFVGLKNVTTGDTLCDEKHPISLESMTFPDPVIEVAVEPKTKADQEKMSLALAKLSDEDPTFQVKTDEESGQTLISGMGELQLDIIVDRMRREFKVECNVGKPQVAYRETIRKAVMNQEYTHKKQTGGSGQFAKVLMNFEPLDTENGEVYEFVNEVTGGHITKEFIPSIDAGVQEAMESGILAGFPVVGVKATVTDGQVHDVDSSEMAFKIAGSMCFKEAAPKAKPVILEPIMAVEVRTPEEYMGDVMGDLNSRRGSIQSMNDATGVKVIDAKVPLSEMFGYIGDLRSKTQGRAMFTMQMDSYAEVPKAVADEIIKAQRGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHO_PROM1
Sequence: MSEQTGKVDDSQSPPKVQKKLRKGDLVKVDREKYSNSLESKASDTNLPEYIFQGPGEVLLIKGDYCQVRWRRPVPDVWMNSDHIVSY
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit O, NAD(P)H dehydrogenase I subunit O, NDH-1 subunit O, NDH-O.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhO subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TRI5_TRIHA
Sequence: MVELNDVPGEEEFPRATYLETMVRLLDTVSYNDENFTDEERVECLKYAYGKAAEHFAQPHVQETLKVPPKRMAAALKTIVGMCVYSWCRVSKEVMADLSIHYTYTLLLDDSREEPAGTMATWYEDLLNARPQAHGWWRLVNDFIPNVLRHYGGYCQMNMVRSTIDFFQGCWIEQHNFKGFRGSSDYPGFLRRINGLGHCVGSSIWPIELVDEEEHFLEITTAIAQMENWMVWTNDLFSFYKEYFAERDQTSLVNNYVECEGITLDQALDKLCKDTIRSSEEIIQVFHDKDPKMYEILTRFIQGYITWHLCDDRYRLVEVYEAAGDDPVAQKFKKYAESARRVGAIDPARYCVPSVTELCEREMAKQSAGRSWDFGLGKIANKISSVAQ
What is the function of this protein?
TS is a member of the terpene cyclase group of enzymes.  It catalyzes the isomerization and cyclization of farnesyl pyro-phosphate to form trichodiene, the first cyclic intermediate in the biosynthetic pathway for trichothecenes.  It serves to branch trichothecene biosynthesis from the isoprenoid pathway.
What are the official names of this protein?
Trichodiene synthase, Sesquiterpene cyclase, TS.
What is the protein family that this protein belongs to?
Belongs to the trichodiene synthase family.
Protein: PUR9_SYNSC
Sequence: MAPVALLSVSDKSGLVPLAEALHRTHGYQLLSSGGTAKVLEQAGLPVTRVSDHTGAPEILGGRVKTLHPRVHGGILAKRGDASHQADLEQQNIAPIDMVVVNLYPFRETIARPDVTWDQAIENIDIGGPAMVRAAAKNHADVAVLTSPDQYDRLLTAMAESGGSVPSALRRQLALEAFNHTASYDTAIGRWMAEQATAKGCPWLEAVPLRQTLRYGENPHQKARWFSHPKQGWGGAIQLQGKELSTNNLLDLEAALATVREFGYGADGSAPASQPAAVVVKHTNPCGVAVGASMPAALTRALDADRVSAFGGIIAMNDVVEATAARELTSLFLECVVAPGFTPEAREVLAAKANLRLLELAPQAIDVAGPDHVRSILGGLLVQDLDDQAITPTDWTVASQRPPTPQEKLDLEFAWRLVRHVRSNAIVVAKDGQSLGVGAGQMNRVGSARIALEAAGEKAQGAVLASDGFFPFDDTVRLAASQGITAVIHPGGSMRDGDSIKACDELGLAMQLTGRRHFLH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: RIP9_SAPOF
Sequence: VTSITLDLVNPTAGQYSSFVDKIRNNVKDPNLKYGGTDIAVIGPPSKDKFLRINFQSSRGTVSLGLKRDNLYVVAYLAMDNTNVNRAYYFRSEITSAELTALFPEATAANHKALEYTEDYHSIEKNAQITEGDKSRKELGLGINLLSSTMDTVNKKVRVVKNEARFLLIAIQMTAEAVRFRYIQNLVTKNFPNKFNSENKVIKFEVNWKKISTAIHGDAKNGVFNKDYDFGFGKVRLVKDLQMGLLMHLGKPK
What is the function of this protein?
Ribosome-inactivating protein of type 1, inhibits protein synthesis in animal cells.
What are the official names of this protein?
Ribosome-inactivating protein saporin-9, SAP-9, SO-9, rRNA N-glycosidase.
What is the protein family that this protein belongs to?
Belongs to the ribosome-inactivating protein family. Type 1 RIP subfamily.
Protein: RS2_ALIF1
Sequence: MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEQTVPMFNEALAELAKIGSKKGKVLFVGTKRAASEAVKEAAINSDQFYVNNRWLGGMLTNYKTVRQSIKRLKDFEVQSQDGTFEKLTKKEALMRTRDMEKLEKSLGGIKNMNGLPDALFVIDADHEHIAIKEANNLGIPVFAVVDTNSNPDGVDYIIPGNDDAIRAIQLYLNAAADAVKSGRNQDVAAVAEKDGFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: FOLD_ALIF1
Sequence: MTAQIIDGKLISQTVRSEVGARVKARVEAGLRAPGLAVVLVGQDPASQVYVGSKRRACEEVGFVSKSYDLPTTTSESELLNLIDELNQDPEIDGILVQLPLPAGMDSTKILEHIDPEKDVDGFHPYNVGRLSQRIPKLRSCTPKGIITLLDRYNIQVRGMHAVVVGASNIVGRPMTLELLLAGCTTTTCHRFTKDLESHIRQADLVVVAVGKPNFIPGEWIKEGAVVVDVGINRLDSGKLIGDVEYDVAKTKASYITPVPGGVGPMTVATLIENTLLACEQYHSK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: KHPA_STRPN
Sequence: MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDVGRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK
What is the function of this protein?
Probably plays a role in PG homeostasis and regulating peripheral PG synthesis.
What are the official names of this protein?
RNA-binding protein KhpA, KH-domain protein A.
What is the protein family that this protein belongs to?
Belongs to the KhpA RNA-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_PYRAR
Sequence: MVKLRIRSSQWYDGVDNAPHRPYLRAVGLTEADFAKPLVGVLVSWSELGPCNFHNLELVRYVKEGVKEAGGVGLAAPTIVVNDGINMGTPGMRYSLISRDLIADTIEAQFNSHGVDAWVGIGGCDKTQPGIMMAMVRLDLPAVYLYGGSAEAGWLGERELTIEDAFESVGAYLAGKITLDELKRVEELSFPTYGTCQGMFTANTMATLGEALGLSLLGSASPPATSARRRKYAVESGRAVLKAAELGVTPRKVVTYDALYNAAVTLFATAGSTNAILHLLAIAHEANVKFTLDDFDEISRRVPVIAALRPAGPYAMQDLDRIGGVPRVLKKLYKAGLLRPEALTVEGEPIGKLLERWEPPAVPEAGILYDVEKPYKPYSGIRILRGNLAPSGAVMKIGAADKLRFEGRAKVYDSEAEAFKAVAAGEIKPGDVVIIRYEGPKGAPGMPEMLKVTAAIVGAGLGDAVALVTDGRFSGATRGIMVGHVAPEAAVGGPIALVQNGDRVIIDGEAGLIKLEVSEEELEKRRKAWAPPPPKYKGGLLAKYAALVQQADKGAVTSPSAWGT
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: ZP3R_MOUSE
Sequence: MITWSFIDLWRTSHSTLFQMTLATVLMAPVLGDCGPPPLLPFASPTNQLYESTTFPSGTVLKYTCHHGFKRVNSSHLSCDENGSWVYSTFCARKRCKNPGELVNGKVEIPSDLLVGSIIEFSCSKGYLLIGSATSRCEVQGKGVDWSDSLPECVIATCEPPPPISNGKHSGRDDDLYTFGSVVIYNCDPTFTLLGNASIVCTVVNRTVGVWRPHPPACQKIVCHRPQIPKGYLAPGFRQFYAYRDALEIRCKKGFILRGSSVIHCEANGEWFPSIPTCEPNGCTNIPDISYASWEGYKFPLRNFEVFEIGAKLKYQCKPGYRASLNDPQTVTCQENLTWSSTNGCERICCPTPDMEKIKIVSERRDFTGTCIYAYGDYVFYICNEGSYPMSTDGRSSCQADGKWDPAIPSCQADSGLQNRLALFTFPNISETNVTNKTYLFGHEENSTEHAMKGVCLKPMVINGNLSVERVIYAELENITIQCDPGYTIVGSPNIICSNRTWYPEVPSCQMEVLEDCRIVSRGAQLLHCLSSPEDVHRALKVYKLFLEIERLEHQKEKWIQLHRKPQSMKINRSFRLCN
What is the function of this protein?
Binds to ZP3 glycoprotein in egg zona pellucida.  Probably involved in interactions between sperm acrosome and egg zona pellucida during and immediately following the acrosome reaction.
What are the official names of this protein?
Zona pellucida sperm-binding protein 3 receptor, Sperm fertilization protein 56, sp56.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome lumen. Note=Sperm acrosomal matrix.
Protein: RL16_LEGPC
Sequence: MLQPKRTKYRKQMKGRNRGLALRGSKISFGEFGLKAVERGRLTARQIEAARRAMTRHIKRGGKIWIRVFPDKPITQKPLEVRQGKGKGSVEYWVAQIQPGKVLFEMEGVSKELAMEAFDLAKAKLPFKVMFEERTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: EI2BA_RAT
Sequence: MEDGELIKYFKSQMKGDPNMASAVAAIQTLLEFLKRDKGETIQGLRAHLTKAIETLCAVDSSVAVSSGGELFLRFISLTSLEYSDYSKCKKIMIERGELFLSRISLSRTKIASLCHAFIKDGARILTHAYSRVVLRVLEEAVAAKKRFSVYITESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKVDLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKSVQAGQDLKEEHPWVDYTSPSLITLLFTDLGVLTPSAVSDELIKLYL
What is the function of this protein?
Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
What are the official names of this protein?
Translation initiation factor eIF-2B subunit alpha, eIF-2B GDP-GTP exchange factor subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family.
Protein: STEEP_PONAB
Sequence: MPKVVSRSVVCSDTRDREEYDDGEKPLHVYYCLCGQMVLVLDCQLEKLPMRPRDRSRVIDAAKHAHKFCNTEDEETMYLRRPEGIERQYGKKCAKCGLPLFYQSQPKNAPVTFIVDGAVVKFGQGFGKTNIYTQKQEPPKKVMMTKRTKDMGKFSSVTVSTIDEEEEEIEAREVADSYAQNAKVIEKQLERKGMSKRRLQELAELEAKKAKMKGTLIDNQFK
What is the function of this protein?
Stimulates membrane curvature formation and subsequent endoplasmic reticulum exit site (ERES) establishment by recruiting PI3K complex I, leading to COPII vesicle-mediated transport (By similarity).  Promotes endoplasmic reticulum (ER) exit of cGAMP-activated STING1 oligomers (By similarity).
What are the official names of this protein?
STING ER exit protein, STEEP.
What is the protein family that this protein belongs to?
Belongs to the STEEP1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Detected in the nucleus and cell soma of various neuronal types.
Protein: UREF_MICAN
Sequence: MLDQKELLCLLQLASPILPVGAYSYSEGLETLVEKGIISNSASLNDWLERSLCQGSIRLETAVLLRVYRCFCQEDFTKLNYWDNWLSATRETAELRQQSWQMGRSLLNLLRELAPARDNLPEQANYATAFAIGASHWQIGEELAVLGYLHSWASNLINAGLRLIPLGQTLGQSLLIGLQPSLLTATADIISLADENLSSWSWGLSFASMNHETQYSRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COCO_LIMPO
Sequence: IVGGFTIGIDTVPY
What is the function of this protein?
Protease that shows preferential cleavage after Arg and Lys residues.
What are the official names of this protein?
Cocoonase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: TRUA_SHESH
Sequence: MRVALGIEYDGRQYFGWQRQAEVDSVQAQLERALSKVANEPIRVHCAGRTDAGVHATGQVVHFETNAIRKDSAWTLGVNVNLPDDIAVRWVKIVDDEFHARFSATARRYRYMIYNYDFRPGILRSGVSHYRGNIDADIMHQAAQQFVGEHDFTSFRALHCQSKTPFRSVHEVNVTRQGMYICVDIKANAFLHHMVRNIVGTLLEIGLGNQRPEWIPQLLDLKDRSQAAPTAKPNGLYMVDVTYPERYELPKLALGPLFMLD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: ERA_STREM
Sequence: MFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIMGIYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDDMIIERLKAARIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEIVPISALQGNNVETLVQLLKDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVDSMKRDEVTDKVHIRVTIMVERDSQKGIIIGKQGAMLKKIGKLARRDIELMLGDKVYLETWVKVKKNWRDKKLDLADFGYNKKEY
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: SECA_PSELT
Sequence: MKIPFFDRNKMLLKKYSKIVEKIKRREERFSKMSNQELINVALEFRKISDPQNHIEDIFAMVRVAAKRTLGMYPFDVQLIGALVLNDGKIAEMKTGEGKTLVATMPLFFNALFGKGVHLVTVNDYLARRDALWMGPLYLFLGMRVGVINQLGKSYEVVWKNQELYEKAISDNLSIWPEDYKNEFLKESAKDRKAVEAFEVELIEITRKEAYVCDITYGTNNEFGFDYLRDNLVFQFDDKVQRGHFYAIVDEVDSILIDEARTPLIISGPSREGASVYRRFASIAKKMSKDIDFTVDEKSRTIILTDKGIEKSEKLLQVDNLYDPSNVSSVYHLLNALKALHLFKKDVDYVVMNQEVVIVDEFTGRLLPGRRYSGGLHQAIEAKEGVPVKEESVTYATITFQNYFKMYEKLAGMTGTAKTEEEEFKQLYDLEVVVIPTHKPMIRKDHDDLIYRTQAEKYTAVVNDVVERYKKGQPVLIGTTSIEKSELLSTMLKKAGIPHQVLNAKYHEKEAEIIAQAGQKGAVTIATNMAGRGTDIKLGEGVADLGGLCIIGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLEDDLLRIFGADQLEKVMNVLKIKPGEPIEHPLLTKLVETVQKRVEGINFSIRKHLMEMDTVLDVQRNSIYSYRDWILSGKVSQYIDEAIEDFVERRIEEFCDGSEWNLEGLKNSLSVLPKDVVSIDSQKFDSEGQMKDFLIRSIKDAYERKRQEIGDEYDQFLKFLILRIIDDNWRQYLEEVDHVKEAVNLRVYGQRDPMIEFKKETFALFDEMIARINEIVVSWMLRVVKVDSKKAEQEAKSGLSNLQLVHEEFNIVNRSERRKLHKNEKIKKRFKVKR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: RNP1_META3
Sequence: MITPYNILRHELIGLDVEITQSTNKSLVGLKGKIVYETRNTINIERFDNSKEVMIPKDIAVFKFKLNEEYIEVIGELLMGRPEDRLKRKIKNIYPY
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 1, RNase P component 1, Rpp29.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VANG2_RAT
Sequence: MDTESQYSGYSYKSGHSRSSRKHRDRRDRHRSKSRDGSRGDKSVTIQAPGEPLLDNESTRGDERDDNWGETTTVVTGTSEHSISHDDLTRIAKDMEDSVPLDCSRHLGVAAGAILALLSFLTPLAFLLLPPLLWREELEPCGTACEGLFISVAFKLLILLLGSWALFFRRPKASLPRVFVLRALLMVLVFLLVISYWLFYGVRILDARERSYQGVVQFAVSLVDALLFVHYLAVVLLELRQLQPQFTLKVVRSTDGASRFYNVGHLSIQRVAVWILEKYYHDFPVYNPALLNLPKSVLAKKVSGFKVYSLGEENSTNNSTGQSRAVIAAAARRRDNSHNEYYYEEAEHERRVRKRRARLVVAVEEAFTHIKRLQEEEQKNPREVMDPREAAQAIFASMARAMQKYLRTTKQQPYHTMESILQHLEFCITHDMTPKAFLERYLAAGPTIQYHKERWLAKQWTLVSEEPVTNGLKDGIVFLLKRQDFSLVVSTKKVPFFKLSEEFVDPKSHKFVMRLQSETSV
What is the function of this protein?
Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate.  Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea.  Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process.  Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity).
What are the official names of this protein?
Vang-like protein 2, Van Gogh-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the Vang family.
Protein: METK_PSE14
Sequence: MSEYSLFTSESVSEGHPDKIADQISDAVLDAIIAEDKYARVACETLVKTGVAIIAGEVSTSAWVDLEDIVRNVILDIGYNSSDVGFDGATCGVMNIIGKQSVDIAQGVDRSKPEDQGAGDQGLMFGYASNETDVLMPAPITFSHQLVQRQAEARKSGLLPWLRPDAKSQVTCRYENGKVVGVDAIVLSTQHNPDVSYKDLREGVMELIVKHVIPAHLLHKDTQFHINPTGNFIIGGPVGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLAERCEIQVSYAIGVAQPMSISLNTFGTGKLSDDKIIKLVRDNFDLRPYAITTMLDLLHPMYQATAAYGHFGRTPVEMTIGDDTFTAFTWEKTDRADALRAAAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYPH_LEGPA
Sequence: MHHSFLSANGGIVVSKQTSHGLRLKHLGIKTYHEAIIYMREDCHVCHSEGFEVQTRIQVTLGQRSIIATLNVVTSELLQPGEAGLSDYAWESLHAKEGDEIQVSHPKPLESLSYVHTKIYGKELSYEQMKVIIDDVLSGRLSDVQISAFLAASSAGRLTRTEIMKLTKAMIDSGDRLSWSSPLVVDKHCVGGLPGNRTTLIVVPIVAAFGLMIPKTSSRAITSPAGTADTMETLAPVHLSPQKMRQVVEQENGCIVWGGAVSLSPADDVLIRVERAIDLDSEGQLVASILSKKIATGATHAVIDIPVGPTAKVRNQSMALLLKQLLEEVGNELGLVVRTLLTDGSQPVGHGIGPSLEARDVMAVLQGLPDAPNDLRERALTLAGAALECSSKVPPGLGKSIATQLLDSGQAFKKFQAICEAQGGMRELTKARFTYPVVAAKAGKVSLIDNRKLAKIAKLAGAPKSKSAGIDLHSHVGESVEKGEPLFTIHSESSGELHYACDLLRDKQDIIILGENS
What are the official names of this protein?
Putative thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.