PharMolix/UniProtQA huggingface dataset:
Protein: RPOB_MYCPA
Sequence: MLEGCILADFRQSKTDRPQSSSNGSSSLNGSVPGAPNRVSFAKLREPLEVPGLLDVQIDSFEWLIGAPRWREAAIARGDAEPKGGLEEVLDELSPIEDFSGSMSLSFSDPRFDEVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTEKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTNEQITERFGFSEIMMSTLEKDNTAGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHAGEPITSSTLTEEDVVATIEYLVRLHEGQPTMTVPGGIEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPIETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVTDEIHYLTADEEDRHVVAQANSPIDDKGRFAEARVLVRRKAGEVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEKSGVIEEVSADYITVMADDGTRHTYRMRKFERSNHGTCANQSPIVDAGDRVEAGQVIADGPCTENGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIVRIGAEVRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDDDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVIGKILPQEDMPFLPDGTPVDIILNTHGVPRRMNIGQILETHLGWVAKSGWNIDGNPEWAVNLPEELRHAQPNQIVSTPVFDGAKEEELAGMLSCTLPNRDGEVMVDGDGKAVLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: KAD_CHESB
Sequence: MRLILLGPPGAGKGTQAQILVEKLHIPQLSTGDMLRAAVKAETEIGKKAKAVMDAGELVSDAIVNAIVAERIDQPDCANGFILDGYPRTLAQADAVEAMLGERGLKLDAVIELVVDDKALVGRIMKRAEDAQAAGQPVRRDDNPEVFEERLREYYKKTAPLVGYYYAKGLLKGVDGMASIDEVTRQIEGILAKA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRFC_DICDI
Sequence: MGRNKITIEKISNERNRQATFTKRKNGLIKKAMELSILCDCEIAMIVFSSNNKLFQYSSRDMDKLLIRYTDNTDNTRKNLTNQDYNRVFGNKKSKNDDEDGDDDGDEDLGETPTTPHGNLNAHPIGSMENNNNNNNNNNNNNNNNNNNINNNNNNNNNSHHNNNNGNNNNNNNNNNNNNSNNNSNNNNSNNGNSNNNNNGNNANHNMHHHNGNSANISPMQMSQQANNNNSNNNNNNGNNNSNSNSNNNNNSNGYQQQQQAAQQAVQQAQMAQQMHLQQQQQYQQLQHIQQQQQQQHQQQQQNMGPNGYNHQQQQLQHQSPPPPPQQQQQQMQHSQQQQNMNGIIGHHSPVIVGNGVSLLQPSKWSASPYGEDLAPLTPRSASYKGIYGNQYPPQMQPVVNSNNNSNGNSNSMNNGISSPPINQQNQQNQKPPIMNKPGGGGQPMYYDYNGYPQQQQPPQNYNSNGGYWGQNVSSPPPPQQQQSANPYIQQQQQPQHQSPYYHGNYSPQQQSPVLNSQNGHHSSPMHPHQMHHQQHQHQQHPQMQQQQQQQQQHQQHPQMQQIQQQQHPQMQQHQQHQQQHPQMQQQHMNNHQINHHHLNSSPEINSQKNVHSSPLIMNSNNNNNNNNNNHHGNDNNNNNNNNSNNNNNNNNSNNNNNINNNINSNSNNNSNVNNGNNNNSGKVYNNNNNSNNGNNNNNKPEQTIPVKIEKEHSSSPTIPEQPSINVSTSSNSAHVFNNITSNSNNNNNNNNNNNNNNNNTNNNNNNNNNNNNNNNTNNINSNNNSSNTNVNVINNSSSSSTPPISPANINTQSPAISPALVPVVTSLNPQGEETSKPKFKKSLNLSIVIPEVGNSKYPPPQCKLTPINVEATKQPDIPTLPSPRDFYPEINLHHDNVSLTPNYWGGWHQTPRGSLLLTGNGGSNNSNSSNNNNNNNNNNNNTNNNNISGNGSSSSSSSSTQNPNGFLGCLSPRSFNFLNENNNNNNNNSSSGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNPDESDQSFNRKRKSMEPKN
What is the function of this protein?
Transcription factor that regulates cell differentiation during development.  Seems to negatively regulate prestalk gene expression and positively regulate prespore gene expression.
What are the official names of this protein?
Transcription factor mef2A, Myocyte enhancer factor 2A, Serum factor response C.
What are the subcellular locations of this protein?
Nucleus.
Protein: SSB_BUCAI
Sequence: MASRGVNKVILIGHLGQDPEVRYMPNGNAVVNMTLATSENWKDKNTGENKEKTEWHRIVLFGKLAEIAGEYLRKGSQVYIEGSLQTRKWQDQNGLERYTTEIIVNIGGTMQMLGNRNSNLQAMTVNDKNSTGIKIKKTDAVEFDKKIETHESNKDLTHSPSEIDFDDEIPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: BGAL2_KLEP7
Sequence: MTMITDSLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEARTDRPSQESRSLNGEWRFAWFPAPEAVPESWLERDLPDADTVIVPSNWQMHGYDAPIYTNVTYPIAVNPPYVPTENPTGCYSLTFNIDESWLQEGQTRIIFDGVNSAFHLWCNGRWVGYGQDSRLPSEFDLSAFLHAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHKPSTQISDFHVATHFNDDFSRAVLEADVQMYGELRDELRVTVSLWQGETQVASGTAPFGGEIIDERGGYADHVTLRLNVENPKLWSAEIPNLYRAVVELHTADGTLIEAEACDVGFREVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSHYPNHPLWYTLCDHYGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRNHPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVQYEGGGADTFATDIICPMYARVDEDQPFPAVPKWSIKKWLSLPGETRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQGGFVWDWVDQSLIKYDENGNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQQQFFQFSLSGRTIEVTSEYLFRHSDNELLHWMVALDGKPLASGEVPLDVAPQGKQLIELPGLPQPKSAGQLWLTVHVVQPNATTWSAAGHISAWQQWRLAENLSVTLPSAPHAIPQLTTSETDFCIELDNKRWQFNRQSGFLSQMWIGDKKQLLTPLRDQFTRAPLDNDIGVSEATRIDPNAWVERWKAAGHYQAEAALLQCTADTLADAVLITTVHAWQHQGKTLFISRKTYRIDGSGQMAITVDVEVASNTPHPARIGLTCQLAQVAERVNWLGLGPQENYPDRLTAACFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNISRYSQQQLMETSHRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGSYHYQLLWCQK
What are the official names of this protein?
Beta-galactosidase 2, Beta-gal 2, Lactase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
Protein: AKIP1_HUMAN
Sequence: MDNCLAAAALNGVDRRSLQRSARLALEVLERAKRRAVDWHALERPKGCMGVLAREAPHLEKQPAAGPQRVLPGEREERPPTLSASFRTMAEFMDYTSSQCGKYYSSVPEEGGATHVYRYHRGESKLHMCLDIGNGQRKDRKKTSLGPGGSYQISEHAPEASQPAENISKDLYIEVYPGTYSVTVGSNDLTKKTHVVAVDSGQSVDLVFPV
What is the function of this protein?
Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA.  Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade.
What are the official names of this protein?
A-kinase-interacting protein 1, Breast cancer-associated gene 3 protein, PKA-interacting protein, Proline-rich protein BCA3.
What are the subcellular locations of this protein?
Nucleus. Note=Locates to punctate spots.
Protein: YBEY_STRR6
Sequence: MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVTNERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGELFISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAYGLTRQ
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_DINSH
Sequence: MKQQAFDVIVIGGGHAGTEAAAAAARLGVQVALITLERSGIGVMSCNPAIGGLGKGHLVREIDAMDGVMGRVADKAGIQFRLLNRRKGPAVQGPRSQSDRDVYRSEMLAEMESLPNLRILEGEVADLITSGTRIEGVCLADGSEVTARAVVVTTGTFLRGIIHIGNRSFQGGRMGAAPSVRLAERFDSFGLPLGRLKTGTPPRLDKRSIAWDKLEPQPGDEDPTLFSFLSAGPHLRQVHCAVTHTNERTHEIIRKNLSRSAMYGGSIEGVGPRYCPSIEDKVVRFSDKTSHQIFLEPEGLDSTTIYPNGISTSLPEDVQEAYVRSISGLENAKITQPGYAIEYDYVDPRALDAALRVKGFDGLYLAGQINGTTGYEEAAAQGLVAGLNAALEGKGKFLPSRMTSYIGVMIDDLITQGVAEPYRMFTSRAEYRLSLRCDNADQRLTPEGLVLGCVGKERRIKFEKKMGLLDETLKKLKSFEVTPKQANEAGIRVNEDGRRRSGLDLLSLSNVSYESLAATWPELQASTEIAKQAKIEATYANYIERQQRDVMALKKDEEIEFPPRFDFSGLSGLSNELKSKLTAVRPSTLGQAARIEGMTPAALTLLLASLRKAEKRRSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_LACP7
Sequence: MKYITIALAKGRLAKKALEILEQIGITCDEMKDPTSRKLIFTNEELKLRFFLAKANDVPTYVEYGAADIGVVGKDTILEEGRKMYEVLDLNLGKCRMCIAGPASAKELLHHGELIRVATKYPNIAKDYFYNKKHQTVEIIKLNGSIELAPIVGLSEVIVDIVETGSTLKENGLEVLEEICPLSARVVVNQVSMKMEHERITKMINDLREVLTEAQ
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAIC_PROMM
Sequence: MQSSSAGGSSHMQVQKLPTGIEGFDDICHGGLPSGRSTLISGTSGTGKTVFSLHFLHNGITQFDEPGIFVTFEESPSDILRNSASFGWNLQEMVEQDKLFILDASPDPDGQDVAGSFDLSGLIERINYAIVKYKAKRVAIDSMTAVFQQYDAISVVRREIFRLIARLKVIGVTTVMTTERIDEYGPIARYGVEEFVSDNVVILRNVLETEKRRRTVEILKLRGTTHMKGEFPFTMGTHGVSVFPLGAMRLTQRSSNVRISSGVPNLDEMCGGGFFKDSIILVTGATGTGKTLLVSKFIEDAFRNQERAILFAYEESRAQLLRNATSWGIDFEEMERQGLLKIICAYPESTGLEDHLEIIKTAIGQFKPSRMAIDSLSALARGVSLNAFRQFVIGVTGYAKQEEIAGFFTNTAEEFMGSHSITDSHISTITDTILLLQYVEIRGEMARAVNVFKMRGSWHDKRIREYVITDNGPQIKDSFSNFERIFSGAPHRITDDERA
What is the function of this protein?
Central component of the KaiBC oscillator complex, which constitutes the main circadian regulator in cyanobacteria.  Its composition changes during the circadian cycle to control KaiC phosphorylation.  Autophosphorylates and has a weak ATPase activity; ATPase activity defines the circadian period.
What are the official names of this protein?
Circadian clock oscillator protein KaiC.
What is the protein family that this protein belongs to?
Belongs to the KaiC family.
Protein: YCGL_SHIDS
Sequence: MPKLGILKSKSMFCVIYRSSKRDQTYLYVEKKDDFSRVPEELMKGFGQPQLAMILPLDGRKKLVNADIEKVKQALTEQGYYLQLPPSPEDLLKQHLSVMGQKTDDTNK
What are the official names of this protein?
Protein YcgL.
Protein: F16PA_CHRVO
Sequence: MSRITLSRFLIEQQRKAGTLPPELRLLIETVGRACKAISYSVNKGALADVLGEAGTGNIQGEAQKKLDVIANDFLLDANEWGGSLAAMASEEMELPYHIPGEYPKGEYLLMFDPLDGSSNIDVNISVGTIFSILRCPEGVTQPTETDFLQPGTHQVAAGYTVYGPQTMLVLTFGSGVHGFTLDREHGSFVLTHPDMKVPERTAEFAINMSNMRHWEAPVRRYVEEMLAGKTGPRGRDFNMRWVASMVAEVHRIITRGGIFMYPKDARDPSKAGKLRLMYEGNPMAFIIEQAGGAATNGHQRILDIVPTKLHERVAVFLGSKEEVELVTRYHSEQQ
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YD526_YEAST
Sequence: MPCLLPPTQVPEAPSISANNGVLFSSFALLFMFFNSLAISLGSKELYRSSRSCTICSSLIPCRTLIFSLWIDFASDSGASVLVCCFSASLPLVFFFWALFSLSLSFQDDIFLGLYNSGNPVPQLLVLRVPLSLLSTESDVSFSTISPSKSITMVAE
What are the official names of this protein?
Putative uncharacterized protein YDR526C.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CAPPA_ARCFU
Sequence: MVPRVMSTQHPDNARIPFFAASEVLNGEDEVREAYYVFSHFKCDEQMWDFEGKEADAHIVRKLLSSYYDFFSSRPLGKDFRLTMRVPNPEIEKGEAKLLAETLEMIPRSYDYVRSLGIEHPPIFEVILPMTRSAEEVMKVHAFYRDFVAGKGRFELLGEKVSDWLGDFLPEEIKVIPLFEDRDSLMRAAEISERYAEWAELDELRVFLARSDPAMNYGFVAATIYVKKALYDLSQLGISTYPILGVGSCPFRGGFSPKNLSVLDEFPSVYTFTVQSAFKYDYEFGDVRRAIKRAKEAARRKSDYVDEEHLQVAEKLKDGYRRRIAKIAEIVNRISSRIPRRRMRKLHVGLFGYSRGEEIKLPRAITFCASLYSIGLPSEIIGIAEMSDKDYEAVCEVFKNFDGMMESAMSLFNPESLKIVDLSMDFERAKELFGYEPDERHLEKTNEIIKQIDGDIKNLVVEAGILRGFLG
What is the function of this protein?
Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 2 family.
Protein: PDXJ_ACIAD
Sequence: MAALLGVNIDHVATLRQARGTRYPDPVSAALVCEQAGAEGITLHLREDRRHIQDDDVRRMRPLLKTRMNLELAVTDEMIAFAKEIQPQHVCFVPERRQEVTTEGGLDVVGQFEKVKAATQTLAAVGCDVSLFIDADLAQIDAAIACGAPTIELHTGAYADAETEEQQQAELQRIIEGVEYAASKGLVVNAGHGLNLDNITPIAAIPQIHELNIGHSIIADSVFVGLAQAVQHMKAAIQAAR
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENTS_ECOSE
Sequence: MNKQSWLLNLSLLKTHPAFRAVFLARFISIVSLGLLGVAVPVQIQMMTHSTWQVGLSVTLTGGAMFVGLMVGGVLADRYERKKVILLARGTCGIGFIGLCLNALLPEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGRENLMQAGAITMLTVRLGSVISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPPPPQPREHPLKSLLAGFRFLLASPLVGGIALLGGLLTMASAVRVLYPALADNWQMSAAQIGFLYAAIPLGAAIGALTSGKLAHSARPGLLMLLSTLGSFLAIGLFGLMPMWILGVVCLALFGWLSAVSSLLQYTMLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGGLGAMMTPVASASASGFGLLIIGVLLLLVLVELRRFRQTPPQVTASDS
What is the function of this protein?
Component of an export pathway for enterobactin.
What are the official names of this protein?
Enterobactin exporter EntS.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. EntS (TC 2.A.1.38) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL4_PROMP
Sequence: MTTLETLKWDGKKAGKVSIDLKVAKETSSADLIHRAVLRQLANKRQGTASTLTRSEVRGGGRKPYKQKGTGRARQGSIRTPLRPGGGVIFGPKPRSYNLDMNRKERRLALRTALMSRISDFKTVEDFGSTLDQPKTSEIINGLSRLGIEKTEKVLVILDNPSDVIKKSINNLEKVKLIAADQLNVFDILNANKLVIGQSAINKIQEVYAS
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RR18_ZYGCR
Sequence: MKTFINKKVSLNKRITFRRRRRKPVQPGERIDYKNLRLLCRFVSKQAKILSRRVSRLTSKQQRTVARYIKSARVLAFMPFVNNET
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EFP_STRE4
Sequence: MIEASKLRAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDVRTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDETAYFMNTETYDQYEIPVANVEQELLYILENSDVKIQFYGTEVIGVQVPTTVELTVTETQPSIKGATVTGSGKPATLETGLVVNVPDFIEVGQKLIINTAEGTYVSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_ACIC1
Sequence: MMRHLLSAGDLTRDDALLILDTAAELARLADRPIKKLPTLRGRTIVNLFYEDSTRTRTSFEAAAKRLSADVINFSAKGSSVSKGESLKDTALTLEAMGTDAVVIRHWASGAPHRLAGWVRGSVINAGDGTHEHPTQALLDAYTIRRHLGGVDGRRVAIVGDILHSRVARSNVTLLHTLGAEVTLVAPPTLLPVGVESWPCAVSYELDGVLPKCDAVMLLRVQRERMQAAFFPTSREYSRRYGLDAARLALLPEHAIVLHPGPMNRGVEIAAEVADSPRSVVVEQVANGVVVRMAVLYLLLGGGEPALAGRAAEPAAAAIGGGW
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RPOC_BRUO2
Sequence: MNQEVMNLFNPQAPAQTFDSIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMKYKGIICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRIGTLLDMTLKDIERVLYFENYIVTEPGLTSLKEHQLLSEEEYMIAVDEFGEDQFTALIGAEAIYELLASMELEKIAADLRVDLAETTSDLKQKKLMKRLKIVENFLESGNRPEWMIMKIVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPGIIIRNEKRMLQEAVDALFDNGRRGRVITGANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAKKLVEKERPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPTLIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQLEARVLMMSTNNILHPANGAPIIVPSQDMVLGLYYLSIVAEKEPGEGMIFADMGELQHALENKVVTLHTKIKGRFKTVDAEGNPVSKIYDTTPGRMIMGELLPKNVNVPFDICNQEMTKKNISKMIDHVYRHCGQKETVIFCDRIMQLGFAHACRAGISFGKDDMVIPESKAKIVAETEALTTEYEQQYNDGLITQGEKYNKVVDAWGKATDKITEEMMARLKAVEFDPVTGRQKQMNSVYMMSHSGARGSVNQMRQLGGMRGLMAKPSGEIIETPIISNFKEGLTVNEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDAIISEVDCGAEIGLTMQPIVDAGQIVASIGQRVLGRTALDPILHPVTGEVIVEAGRMIEEKDVEIIEKAGIQSIRIRSALTCETRNGVCAKCYGRDLARGTPVNQGEAVGVIAAQSIGEPGTQLTMRTFHLGGTAQVVDSSYLEASYEGTVKLRNRNVVRNSDGNLVVMGRNMAVLILDATGKERAVHRVTYGSRLFVDEGDTVKRGQRIAEWDPYTRPIMTEVEGYVEFEDLVDGLSVSETADESTGITKRVVIDWRSTPRGSDLKPAMVIKDKAGKILKLSKGGDARFLLSVESILSVEPGAHVKAGDVIARLPMESAKTKDITGGLPRVAELFEARRPKDHAIIAEIDGTVRFGRDYKNKRRIIIEPNDDTIEPVEYLIPKGKPFHLQDGDVIEKGEYILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVLINDKHIEVIVRQMLQKVEITESGDTGYIPGDHVDRIELEEINERLIEEGKKPGSGNPVLLGITKASLQTPSFISAASFQETTRVLTEAAVAGKMDTLQGLKENVIVGRLIPAGTGGMTNQIRRIATARDELIIDERRKTSGSAEANAMLVDMTNNAAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RFC5_YEAST
Sequence: MSLWVDKYRPKSLNALSHNEELTNFLKSLSDQPRDLPHLLLYGPNGTGKKTRCMALLESIFGPGVYRLKIDVRQFVTASNRKLELNVVSSPYHLEITPSDMGNNDRIVIQELLKEVAQMEQVDFQDSKDGLAHRYKCVIINEANSLTKDAQAALRRTMEKYSKNIRLIMVCDSMSPIIAPIKSRCLLIRCPAPSDSEISTILSDVVTNERIQLETKDILKRIAQASNGNLRVSLLMLESMALNNELALKSSSPIIKPDWIIVIHKLTRKIVKERSVNSLIECRAVLYDLLAHCIPANIILKELTFSLLDVETLNTTNKSSIIEYSSVFDERLSLGNKAIFHLEGFIAKVMCCLD
What is the function of this protein?
Component of ATP-dependent clamp loader (RFC and RFC-like) complexes for DNA clamps, such as the POL30/PCNA homotrimer and the checkpoint clamp DDC1:MEC3:RAD17 complex.  During a clamp loading circle, the RFC:clamp complex binds to DNA and the recognition of the double-stranded/single-stranded junction stimulates ATP hydrolysis by RFC.  The complex presumably provides bipartite ATP sites in which one subunit supplies a catalytic site for hydrolysis of ATP bound to the neighboring subunit.  Dissociation of RFC from the clamp leaves the clamp encircling DNA.  Component of the replication factor C (RFC or activator 1) complex which loads POL30/PCNA and acts during elongation of primed DNA templates by DNA polymerase delta and epsilon.  RFC has an essential but redundant activity in sister chromatid cohesion establishment.  Component of the RFC-like complex CTF18-RFC which is required for efficient establishment of chromosome cohesion during S-phase and may load or unload POL30/PCNA.  Component of the RFC-like RAD24-RFC complex which loads the checkpoint clamp DDC1:MEC3:RAD17 complex and is involved in DNA repair pathways.  Component of the RFC-like ELG1-RFC complex which appears to have a role in DNA replication, replication fork re-start, recombination and repair.
What are the official names of this protein?
Replication factor C subunit 5, Replication factor C5, Activator 1 40 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSAC_CUCSA
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWGGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLWHETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PS 1 subunit 11, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: ABCG2_MACMU
Sequence: MSSSNVEVFIPMSQENTNGFPTTTSNDRKAFTEGAVLSFHNICYRVKVKSGFLPGRKPVEKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGALRPTNFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLPTTMTNHEKNERINRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIINGDSTAVALNREEDFKATEIIEPSKRDKPLVEKLAEIYVDSSFYKETKAELHQLSGGEKKKITVFKEISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVILGLVIGAIYFGLNNDSTGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFFGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPTADAFFIMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATVNNTCNYATCTGEEYLAKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKYS
What is the function of this protein?
Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes a wide variety of physiological compounds, dietary toxins and xenobiotics from cells.  Involved in porphyrin homeostasis, mediating the export of protoporphyrin IX (PPIX) from both mitochondria to cytosol and cytosol to extracellular space, it also functions in the cellular export of heme.  Also mediates the efflux of sphingosine-1-P from cells.  Acts as a urate exporter functioning in both renal and extrarenal urate excretion (By similarity).  In kidney, it also functions as a physiological exporter of the uremic toxin indoxyl sulfate (By similarity).  Also involved in the excretion of steroids like estrone 3-sulfate/E1S, 3beta-sulfooxy-androst-5-en-17-one/DHEAS, and other sulfate conjugates (By similarity).  Mediates the secretion of the riboflavin and biotin vitamins into milk.  Extrudes pheophorbide a, a phototoxic porphyrin catabolite of chlorophyll, reducing its bioavailability (By similarity).  Plays an important role in the exclusion of xenobiotics from the brain.  It confers to cells a resistance to multiple drugs and other xenobiotics including mitoxantrone, pheophorbide, camptothecin, methotrexate, azidothymidine, and the anthracyclines daunorubicin and doxorubicin, through the control of their efflux (By similarity).  In placenta, it limits the penetration of drugs from the maternal plasma into the fetus.  May play a role in early stem cell self-renewal by blocking differentiation (PubMed:15516692).
What are the official names of this protein?
Broad substrate specificity ATP-binding cassette transporter ABCG2, ATP-binding cassette sub-family G member 2, Urate exporter.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Mitochondrion membrane; Multi-pass membrane protein. Note=Enriched in membrane lipid rafts.