PharMolix/UniProtQA huggingface dataset:
Protein: TPIS_CALMQ
Sequence: MKVPVLIINMKAYPELLGGGAVKLAQVAEKVANNLGASIIVAPPHTYLRQVAESVNIPVYAQSADPVDPGARTGHIPLEFIKDAGASGVIINHSEHRLLLNDIAMLVNKAKALNLETVVCSPDPLSSAAAAALAPTAVAMEPPELIGTGKSVSRTKPDVVVETVNAVKRVNGDVKVITGAGIEDYNDVAKAIELGTVGVLVASAIVKAKDWEAKITELAKPLVGK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHM_RIPO1
Sequence: MLLKSTTRHIRLYTAEIKNSELVPSDNVLTLDVDPDNEFNWGEDSLQKVYRKFDELVESYSGQDLTDYNLRRIGSDLEHFIRSLLQKGDISYNLQSRVLNYSMGLPKVESPETEGKYR
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit M, NAD(P)H dehydrogenase I subunit M, NDH-1 subunit M, NDH-M.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhM subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y2215_HALMD
Sequence: MCPRPRRAVLLGLGVAMSAIAGCRETAPSTTQTSDGGPEPTGRSGDTQTDGGGETTRQATVAEGGESATRADETETSELDLREANVVDVTLQSAGGRAVEFSVTLYHDDDGEDGYADWWQVETLAGDRLGRRELLHAHSTAPFTRSETIEVPEGTTCVVVRGHDQTHGYGGQAMVVDTESGATRAVQQGPEPAEFDDGDCP
What are the official names of this protein?
Putative lipoprotein Hmuk_2215.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RPIA_COXB1
Sequence: MSKNELKKAAAMEAIQFVKNVNIVGVGTGSTVNYFIDALAEIKHQIEGAVASSVATENRLKEHRIPVVDLNSVSNVDVYVDGADEFNKHFYLTKGGGGALTREKIIAAAAKRFICIVDESKQVDVLGQFPLPIEVIPMARSFVAREIVKLKGDPVYRQGFTTDNGNVILDIHNLTILNPVELEAILNNIPGVIANGLFAQQPADDLLIGTPAGVQLHHRK
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: AROK_METM6
Sequence: MRCSAVSLGSGTIINAIATGFGSAFGVDLKIKADVELVDNGKKIINGISIDNPTLKPSLVERCVKNVLNYFEVDYSAKISTNGDIPIKSGLSSSSAASNAAVLATIGALGEKVDSDLVLDLAIKSSFEEKLTVTGAYDDATASYFGGITVCNNMERKILKKDEFKEDIKVIVLMPEFEKNVDVNRMKLIKDYVDMAFEKCIAGDYYKALFLNGLLYSSALNFPSNISVDALEAGAITAGLSGTGPSYVALCYSEDEKNVENALKKYGNTVITKPSTNGARILY
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UCSJ_ACRSP
Sequence: MTKKIFATGATGYIGGDAIYALLSASPEYEVSCLVRSGAKATELVARHPSVRIVDGTLDDLELLEEAAANADIVCNFAHATHEPSVSALAKGLARRQRPGHGYLIHTMGSGTMIYDDVIQRRFGEHSDKVFNDVEGLPEVLAVPDFAKARGAENAVRDVGVKNPDRVRTAVVCTGSAYGPGRGLVEYRTSAIHELVRCTLSRGHALQVGAGKSAWRNVYIRDLSDVFVKLITHATNDEQDSDNTDESVWGGSGGYYFVENGEHVWGELARAISDEAVAQGLIQGGDIESIDAAEAASLAPMCNFFWGCNARVEGRRAARGLNWKPVGPPLVKELEVIVQKEAEKLGLS
What is the function of this protein?
Oxidase; part of the gene cluster that mediates the biosynthesis of UCS1025A, a member of the pyrrolizidinone family that acts as a strong telomerase inhibitor and displays potent antibacterial and antitumor properties (PubMed:29373009).  These compounds share a hemiaminal-containing pyrrolizidinone core fused with a gamma-lactone, giving a furopyrrolizidine that is connected to a decalin fragment (PubMed:29373009).  The polyketide synthase module (PKS) of the PKS-NRPS ucsA is responsible for the synthesis of the polyketide backbone via the condensation of an acetyl-CoA starter unit with 6 malonyl-CoA units (PubMed:29373009).  The downstream nonribosomal peptide synthetase (NRPS) module then amidates the carboxyl end of the polyketide with a 2S,3S-methylproline derived from L-isoleucine by the 2-oxoglutarate-dependent dioxygenase ucsF which converts L-isoleucine to (4S,5S)-4-methylpyrroline-5-carboxylate that is further converted to 2S,3S-methylproline by the pyrroline-5-carboxylate reductase ucsG (PubMed:29373009).  Reductive release of the completed aminoacyl polyketide from the assembly line can form the 3-pyrrolin-2-one structure via an intramolecular Knoevenagel reaction (PubMed:29373009).  Because ucsA lacks a designated enoylreductase (ER) domain, the required activity is provided the enoyl reductase ucsL (PubMed:29373009).  This keto acyclic precursor is the substrate of the Diels-Alderase ucsH, that catalyzes the Diels-Alder cycloaddition (PubMed:29373009).  Oxidation of the 3S-methyl group to a carboxylate by the cytochrome P450 monooxygenase ucsK allows an oxa-Michael cyclization that might involve the reductase/dehydrogenase ucsI and which furnishes the furopyrrolizidine (PubMed:29373009).  The oxidase ucsJ likely plays a critical role in stereoselective reduction of the C5-C6 double bond to afford the required R-configured carboxylate group (Probable).  Further enolization and oxidation at C5 by an unidentified enzyme affords the last intermediate that can undergo oxa-Michael cyclization to yield UCS1025A (Probable).
What are the official names of this protein?
Oxidase ucsJ, UCS1025A pyrrolizidinone biosynthesis cluster protein J.
What is the protein family that this protein belongs to?
Belongs to the avfA family.
Protein: PAND_POLNA
Sequence: MFRTLLKSKIHRAAVTHCELNYEGSCAIDEDLLDAANLGENEQIHIWNINNGERFITYAIRAERGSRIISVNGSAARRAAVGDLVIIAAFAQVEEKEVAGFSPKLVFVNPDNRIKEERSTIPVQMAD
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APEB_MYCBT
Sequence: MAATAHGLCEFIDASPSPFHVCATVAGRLLGAGYRELREADRWPDKPGRYFTVRAGSLVAWNAEQSGHTQVPFRIVGAHTDSPNLRVKQHPDRLVAGWHVVALQPYGGVWLHSWLDRDLGISGRLSVRDGTGVSHRLVRIDDPILRVPQLAIHLAEDRKSLTLDPQRHINAVWGVGERVESFVGYVAQRAGVAAADVLAADLMTHDLTPSALIGASVNGTASLLSAPRLDNQASCYAGMEALLAVDVDSASSGFVPVLAIFDHEEVGSASGHGAQSDLLSSVLERIVLAAGGTREDFLRRLTTSMLASADMAHATHPNYPDRHEPSHPIEVNAGPVLKVHPNLRYATDGRTAAAFALACQRAGVPMQRYEHRADLPCGSTIGPLAAARTGIPTVDVGAAQLAMHSARELMGAHDVAAYSAALQAFLSAELSEA
What are the official names of this protein?
Probable M18 family aminopeptidase 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M18 family.
Protein: RL10_BURM9
Sequence: MPLNREDKQAVVAEVAAQVAKAQTVVLAEYRGIAVGDLTTLRAKAREQKVYLRVLKNTLARRAVEGTPFAPLAEQMTGPLIYGISEDAIAAAKVVHDFSKSNDKLVIKAGSYDGKVMDKAGVQALASIPSREELLSKLLFVMQAPVSGFARALAALAEKKQAEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: T1R1_MYCPN
Sequence: MFLTGFDAPTLNTLWVDKNLSEHTLIQAFSRTNRCFGETKKFGNIFSFRDIRENFDQALKMYADKRGLKDIKSNMVMREFEEVFEKFKDWTEKIKQKYPNPDEILNLEKEEKWDFSDLFGEFLGDYRTVKSYHEFDKDNPYLPSDEFNKYFAAFSQIQEEIRKEKAEKKALEVQEEDLSNEVRKEPQIFSWEYGEGIQANLDYIFHLIKDLYNCDNEQDRQKVLDKIKTAIRTNPEIQVNEDILNEFIEDLGKSFEKEKLEEVWKTEGKLRECLKDFCKKKEESNKKKIINDFLVKGVFLVEWVADKQLNTAKKKGEYSPSWSDTEKLIWKEKSTNLPTMTEKDEDGNFKWRKLITDISEAFKNHFERFIRFVEIR
What is the function of this protein?
The N-terminal section of a putative type I restriction enzyme that if reconstituted might recognize 5'-GAN(7)TAY-3' and cleave a random distance away (Probable).  Subunit R is required for both nuclease and ATPase activities, but not for modification (PubMed:12654995).
What are the official names of this protein?
Putative type I restriction enzyme MpnIIP endonuclease subunit N-terminal part, R protein N-terminal part, Putative type I restriction enzyme MpnORFDP endonuclease subunit part 1, MpnORFDAP.
Protein: YBEY_THEAB
Sequence: MVTTNKQIEEGYLKYMDEILKTEIGKDVNVNLVFIDKGEIERLNNQYRNINAPTDVLTFVYGDDDLYAEIFVCEDVIKENAEKFYNTFEKELLTVLIHAALHVAGYDHEYDTTNAKEMFQKQEEYLKKYDVDNN
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG037_VACCW
Sequence: MIFVIESKLLQIYRNRNRNINFYTTMDNIMSAEYYLSLYAKYNSKNLDVFRNMLQAIEPSGNNYHILHAYCGIKGLDERFVEELLHRGYSPNETDDDGNYPLHIASKINNNRIVAMLLTHGADPNACDKHNKTPLYYLSGTDDEVIERINLLVQYGAKINNSVDEEGCGPLLACTDPSERVFKKIMSIGFEARIVDKFGKNHIHRHLMSDNPKASTISWMMKLGISPSKPDHDGNTPLHIVCSKTVKNVDIIDLLLPSTDVNKQNKFGDSPLTLLIKTLSPAHLINKLLSTSNVITDQTVNICIFYDRDDVLEIINDKGKQYDSTDFKMAVEVGSIRCVKYLLDNDIICEDAMYYAVLSEYETMVDYLLFNHFSVDFVVNGHTCMSECVRLNNPVILSKLMLHNPTSETMYLTMKAIEKDRLDKSIIIPFIAYFVLMHPDFCKNRRYFTSYKRFVTDYVHEGVSYEVFDDYF
What is the function of this protein?
Inhibits host apoptosis.  Acts by associating with host apoptosome.
What are the official names of this protein?
Inhibitor of Apoptosis OPG037, Ankyrin repeat protein M1.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG037 protein family.
Protein: MSHC_MYCTA
Sequence: MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYVTFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRVLPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDRDTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSRIGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLVLVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDVVARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL
What is the function of this protein?
Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
What are the official names of this protein?
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, L-Cys:GlcN-Ins ligase, Mycothiol ligase, MSH ligase.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
Protein: DTD_ESCF3
Sequence: MIALIQRVTRASVTVEGEVTGEIGAGLLVLLGVEKDDDEQKANRLCERVLGYRIFSDAEGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSKGASPDRAEALYDYFVERCRQQEMNTQTGRFAADMQVSLVNDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBJ_RHDSA
Sequence: MASTGRIPLWLIATVGGTAALTVVGLFFYGSYSGVGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PSBH_PINTH
Sequence: MATQTIDDTSKTTPKETLVGTTLKPLNSEYGKVAPGWGTTPLMGFAMALFAVFLSIILEIYNSSVLLDGIPVSWG
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H, Photosystem II 10 kDa phosphoprotein.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: WDR51_CAEEL
Sequence: MDTSENAASAAEQQPTQQIDQLTVPNAPDGGSSAPAPSTSPNSISPSNPTGTPAPGASAQTPNPNAAGASASGSANYKLMCTLEGHTKSISSAKFSPCGKYLGTSSADKTVKIWNMDHMICERTLTGHKLGVNDIAWSSDSRCVVSASDDKTLKIFEIVTSRMTKTLKGHNNYVFCCNFNPQSSLVVSGSFDESVRIWDVKTGMCIKTLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIWDTANGQCIKTLVDDENPPVAFVKFSPNGKYILASNLDSTLKLWDFSKGKTLKQYTGHENSKYCIFANFSVTGGKWIISGSEDCKIYIWNLQTREIVQCLEGHTQPVLASDCHPVQNIIASGALEPDNKIHIWRSDV
What is the function of this protein?
Contributes to histone modification (PubMed:16710447, PubMed:17967446, PubMed:20188723, PubMed:20555324, PubMed:21455483, PubMed:22012258).  May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4' (PubMed:21455483).  Required for di- and trimethylation, particularly for the trimethylation at 'Lys-4' of histone H3 (PubMed:20555324, PubMed:21455483, PubMed:24682813, PubMed:21527717).  Not required for demethylation of histone H3 'Lys-27' (PubMed:21455483).  H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, germline establishment, maintenance and function (PubMed:21455483).  Implicated in the epigenetic inheritance of lifespan over several generations (PubMed:22012258).  Acts in the germline to limit the longevity of the soma, probably by regulating a lipid metabolism pathway that signals from the germline to the intestine, thereby preventing accumulation of mono-unsaturated fatty acids (PubMed:17967446, PubMed:20555324, PubMed:28379943).  Required for RNA interference with probable antagonistic role against hpl-2 function (PubMed:17967446).  Plays a role in vulval cell fate specification by acting in the synthetic multivulva pathway independent of set-2 (PubMed:17967446).  Sex determining protein required in the germline to promote the spermatogenesis to oogenesis switch during the late larval stages of development (PubMed:24682813).  Acts with the sex determining factor tra-1, and redundantly with wdr-5. 2, to regulate fog-3 expression, which in turn determines germ cell fate (PubMed:24682813).  Cooperates with jmjd-3. 1, egl-27 and unc-3 to ensure robust transdifferentiation of the Y rectal cell to the PDA motor neuron during larval development (PubMed:25124442).
What are the official names of this protein?
WD repeat-containing protein wdr-5.1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR5/wds family.
What are the subcellular locations of this protein?
Nucleus. Note=Localized on chromatin in the nucleus.
Protein: KDPB_ECOL5
Sequence: MSRKQLALFEPTLVVQALKEAVKKLNPQAQWRNPVMFIVWIGSLLTTCISIAMASGVMPGNALFSAAISGWLWVTVLFANFAEALAEGRSKAQANSLKGVKKTAFARKLREPKYGAAADKVPADQLRKGDIVLVEAGDIIPCDGEVIEGGASVDESAITGESAPVIRESGGDFASVTGGTRILSDWLVIECSVNPGETFLDRMIAMVEGAQRRKTPNEIALTILLIALTIVFLLATATLWPFSAWGGNAVSVTVLVALLVCLIPTTIGGLLSAIGVAGMSRMLGANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASEFIPAQGVEEKALADAAQLASLADETPEGRSIVILAKQRFNLRERDVQSLHATFVPFTAQSRMSGINIDNRMIRKGSVDAIRRHVEANGGHFPADVDQKVDQVARQGATPLVVVEGSRVLGVIALKDIVKGGIKERFAQLRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQAEGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVHIGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNIMRLHSPDSAILSAVIFNALIIVFLIPLALKGVSYKPLTASAMLRRNLWIYGLGGLLVPFIGIKVIDLLLTVCGLV
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ENO_LEPIC
Sequence: MSHHSQIQKIQAREIMDSRGNPTVEVDVILLDGSFGRAAVPSGASTGEYEAVELRDGDKHRYLGKGVLKAVEHVNLKIQEVLKGENAIDQNRIDQLMLDADGTKNKGKLGANAILGTSLAVAKAAAAHSKLPLYRYIGGNFARELPVPMMNIINGGAHADNNVDFQEFMILPVGAKSFREALRMGAEIFHSLKSVLKGKKLNTAVGDEGGFAPDLTSNVEAIEVILQAIEKAGYKPEKDVLLGLDAASSEFYDKSKKKYVLGAENNKEFSSAELVDYYANLVSKYPIITIEDGLDENDWDGWKLLSEKLGKKIQLVGDDLFVTNIEKLSKGISSGVGNSILIKVNQIGSLSETLSSIEMAKKAKYTNVVSHRSGETEDVTISHIAVATNAGQIKTGSLSRTDRIAKYNELLRIEEELGKSAVYKGRETFYNL
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: YIDD_STRPC
Sequence: MMKKLLIVSVKAYQKYISPLSPPSCRYKPTCSAYMLTAIEKHGTKGILMGIARILRCHPFVAGGVDPVPEDFSLMRNKNTSKNAEKA
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RBL_PROMA
Sequence: MSKKYDAGVKEYRDTYWTPDYVPLDTDLLACFKCTGQEGVPREEVAAAVAAESSTGTWSTVWSELLTDLEFYKGRCYRIEDVPGDKESFYAFIAYPLDLFEEGSITNVLTSLVGNVFGFKALRHLRLEDIRFPMAFIKTCGGPPQGIVVERDRLNKYGRPLLGCTIKPKLGLSGKNYGRVVYECLRGGLDLTKDDENINSQPFQRWRDRFEFVAEAVKLAQQETGEVKGHYLNCTATTPEEMYERAEFAKELDMPIIMHDYITGGFTANTGLANWCRKNGMLLHIHRAMHAVIDRHPKHGIHFRVLAKCLRLSGGDQLHTGTVVGKLEGDRQTTLGYIDNLRESFVPEDRTRGNFFDQDWGSMPGVFAVASGGIHVWHMPALLAIFGDDSCLQFGGGTHGHPWGSAAGAAANRVALEACVKARNAGREIEKESRDILMEAAKHSPELAIALETWKEIKFEFDTVDKLDVQ
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Carboxysome.
Protein: UPP_BACAC
Sequence: MGKLYVFDHPLIQHKITYIRDKNTGTKDFRELVDEVASLMAFEITRDLPLKDIEIETPVSKATTKVIAGKKLGLIPILRAGLGMVDGILKLIPAAKVGHVGLYRDPKTLQPVEYYVKLPTDVEERDFIVLDPMLATGGSAAEAINSLKKRGAKQIKLMCIVAAPEGVKVVQEEHPDVDIYVAALDEKLNDHGYVVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: MDCG_PSEPG
Sequence: MNAPRPHDLLWGMPVSALPADAPQWALDVLAGAQPVVVRRAICDHGWVAVGLRGQGRTQRFAALMRLVDIQRQQGPEALRGPGQSPWPALQALASVAPVLNASGLAWGPTGGAGYQIATGIEVLHTGSDLDLLLHTPQPLARAQARELLDILDCAPCRIDVQLETPAGAVALREWAGFARRVLLKSDHGPRLVGDPWAAQERAA
What is the function of this protein?
Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme-A to the apo-[acyl-carrier-protein] of the malonate decarboxylase to yield holo-[acyl-carrier-protein].
What are the official names of this protein?
Phosphoribosyl-dephospho-CoA transferase, Malonate decarboxylase holo-[acyl-carrier-protein] synthase, Holo-ACP synthase.
What is the protein family that this protein belongs to?
Belongs to the MdcG family.
Protein: FIS_PSYIN
Sequence: MFEQKISSEALTTTTSIPATGQITQRPLRDSVRQAVSGYVAQLNGQDPTELYELVLSEVEAPLLDIIMQYTRGNQTRAATMLGINRGTLRKKLKKYGMG
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: RLME_HALLT
Sequence: MSGKDEYYNKSKQQGYRARSAYKLKQIDEEANLFERGDTVVDLGAAPGGWLQVAAEEVGESGTVVGVDLQRIDDLDDHDVETIRGDMTEERTRHYLREAIGERGADVVISDMAPNMTGEYALDHARSVHLARQAFDVAEELLAPGGDFVVKVFQGEDLDAFREDVRAEFEYLRTVSPPASRDSSSEVYLVAKGLNTAPVAAGDRIEVTVEERGDEGDGIAYVEGYSIFVSDADVGETVTVEVVDAKPRFGFATRVDVGTPDSDESDEGE
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1390_LYSSC
Sequence: MDTKSQTSFQEKALELLIADADKIARLIRVQMDHLTMPQCPLYEEVLDTQMFGLSREIDFAVKLGLIEREKGKEILDSLEKELSVLHDAYTDK
What are the official names of this protein?
UPF0358 protein Bsph_1390.
What is the protein family that this protein belongs to?
Belongs to the UPF0358 family.
Protein: HEM6_PSEAE
Sequence: MTDRIAAVKTYLLDLQDRICAALEAEDGKARFAEDAWERPAGGGGRTRVIGDGALIEKGGVNFSHVFGDSLPPSASAHRPELAGRGFQALGVSLVIHPENPHVPTSHANVRFFCAEKEGEEPVWWFGGGFDLTPYYAHEEDCVHWHRVARDACAPFGADVYPRYKEWCDRYFHLKHRNEPRGIGGLFFDDLNQWDFDTCFAFIRAIGDAYIDAYLPIVQRRKHTPFDERQREFQAYRRGRYVEFNLVFDRGTLFGLQSGGRTESILMSLPPQVRWGYDWKPEPGSEEARLTEYFLADRDWLAGQP
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.