PharMolix/UniProtQA huggingface dataset:
Protein: SSUB3_PARXL
Sequence: MTLDFALSQDAAVPAFTEEPVNPSPLAVSVRGLQRRYGARVVIDALDLDIREGEFVALLGESGCGKTTLLRALAGLDLPDAGQIRAPERPSVVFQEHRLLPWATLWENVALGHETTVGRAGAARALAEVGLSGREDDWPRNLSGGQAQRVALARGLARDPALLLLDEPFAALDALTRIKMHGLVKELVARHHPGVLLVTHDVDEALTLADRILVMRSGRIAASFQPETHTPQALRSILLEELGVQSL
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB 3.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RSMG_VEREI
Sequence: MMTSLGNDVLRARLQSGAEVLAPGLDAAQIDRLMDFLALLQKWNRVYNLTALQDPQEMLTQHLLDSLAALAPLRRQLAHLAHLAHSTGLAGPGQGAGPRRLLDVGSGAGLPGVVFAICCPQLDVHCVDSVGKKAAFIGQVALQLRLRNLHGVHARVETLTTPFEIICCRAFAALPDFVRWTRSALRAPDGVWLALKGKHPGAEIAALPADVQVFHVERLTVPGLAAERCIVWLRPAALA
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_PARMW
Sequence: MPDVPALMLSLSNTLDAQLRAAMQRAFPVADAVLDPQLAPASKPEFGDFQANGALPLAKPLKQAPRQIATAIVEQLQADSGFTDLCLEPQIAGPGFINLTIRPERLAAEVSARLGDERLGVPAVEQAAPVVVDFSSPNIAKEMHVGHLRSTIIGDSLARVLEFRGHTVLRLNHVGDWGTQFGMLITHLKQVAPDALETADAVDLGDLVAFYREAKKRFDDDEAFQSTSREEVVKLQGGDPVSLKAWGLLCDQSRREFQKIYDRLDIRLNERGESFYNPFLPAVIDGLKAAELLVTDDGAQCVFLEGVQGKDGKPLPVIVQKSDGGFNYATTDLAAIRYRFGAAPDGDGARRVVYVTDAGQANHFAGVFQVAERAGWIPDGARLEHVPFGLVQGEDGKKLKTRAGDTVRLRDLLDEAVERAETDLRSRLKEEERSESEEFIQNVAGTVGLAAVKYADLSQNRITNYQFSFDRMLALQGNTAPYLLYAVVRIAGIARKGGDLEVSTGQLQFSEPQEWALVRELLKFDSVIAEVEEELLPNRLCSYLFELSQVFNRFYDQVPVLKADPEALASRLALCRLTADTLRLGLGLLGIATLDRM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_PROMA
Sequence: MAETNHSKRISELRSLLNKANHAYYILDSPLIEDAVFDRLYRELIELEKQYPSLVTPDSPSQRLGNKPATKFESIKHRIPLQSLDNAFNFDELNYWHSRMQKHLKSHSAMVCELKIDGNALALSYVNGVLTRGATRGDGAEGEEITANVKTIVSIPLSLHLQNPPAWVEIRGEAFIPNKVFISLNKERLKEEKQLFANPRNACSGTLRQLDSRIVASRHLDFFAYTIHLPDDWIPGETDPKKPKGQWEALLWLKAAGFRVNPNAKLISQPDQVEKFCIDWEKRRHQLPYTTDGIVIKIDDFKLQKTLGITQKAPRWAIALKYPAEEAPTQLNKLIFQTGRTGTVTPVAEFNPIPLGGTLVSKATLHNANRLSELDIHEGDTIVIRKAGEIIPEVIRVIKELRPNNAKKLVLPEKCPECNSKLLKETGEAATKCLNNDCPAILRGVLRHWVSKGAMNIDGFGTKLVEQLVKRKIIKSIAGIYELKEKNLENLERMGTKSAEKLLIEINNSKKQPWHKQLYGLGILHIGEANAKAIAEVFPSISLLADAAIASPESISNIYGIGSEITESLHKWFNCSINQNLIKELKDLGIALERVNEEGAIDNILMQEKLQFSGKTFVITGTMPSLSRANLEELIEREGGKVNSSVSSKTNYLVAGEKPGNKLKKAKELGIKVINEQELMTLISN
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: YIOE_SCHPO
Sequence: MNLLSHQLRDRFPIKAIISKADEVIFANYKHTNDFFKITATTYALINSVIVSNNCCNRRFHSTWQKKKHDDLTATVPVIDFRKNQKLTSIVVNAIQAIYWYARRSNCLTGINEAEYIWKSLIPESIFYHFVSLQSFIRKYLTDVFYCSAQKVILLSTDDSVVSSEKLYIRIASILSNANDKVSFKESSINTNTVFKDVYVEVSSHNDEFLLKNSSKCWAFTSLLVDPLHFMFSQIVFEDLSGKKIMKFEDTAVSTASNHSKQFTKGNLLAIKYIGGLYNAVYLMGLKKNLLAFVENEKDDLFVAKIFLLAYSSSKNRKKIVPVDVWDAMIDSLYETINVEETKKETYKFTRSIKTVIPNKLISNESISILSIPESEKTIYQNFDLYVSKFNVARKELSEKELFNNSFSSSFNTLLASLLVKPTLCLISYLMIAKKMVVLQEANRLFLKSFAHPFHLERYHLHAVAAMGGLYQIMSSTHLKNLFFCSRKGIALTKLHSQQYNESTLFQYLSEFVHQRQKSLTPKQRIAIQELILKFMQRNFENSLYHQSFSSHWFISRLLINPIRMLCWHITDVGKTLDLGEAEKLLKYNHKQCPYIIYPSSLKAVQKLGGLQCIIRNDNLSHIFNCSRKYIRVQRYSDDDLSESSLLPRLVNLLLFFENSMGEVAWNKLSQTLMDMFEKETKSNSLSDY
What are the official names of this protein?
Uncharacterized protein SPAP27G11.14c.
Protein: PSBF_THAPS
Sequence: MTKNINQPVAYPIFTFRWLAVHGLAIPTVFFLGGITAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CVFB_STAAB
Sequence: MALDKDIVGSIEFLEVVGLQGSTYLLKGPNGENVKLNQSEMNDDDELEVGEEYSFFIYPNRSGELFATQNMPDITKDKYDFAKVLKTDRDGARIDVGLPREVLVPWEDLPKVKSLWPQPGDHLLVTLRIDRENHMYGRLASESVVENMFTPVHDDNLKNEVIEAKPYRVLRIGSFLLSESGYKIFVHESERKAEPRLGESVQVRIIGHNDKGELNGSFLPLAHERLDDDGQVIFDLLVEYDGELPFWDKSSPEAIKEVFNMSKGSFKRAIGHLYKQKIINIETGKITLTKKGWSRIDSKE
What is the function of this protein?
Contributes to the expression of virulence factors and to pathogenicity.  Involved in the production of hemolysin, DNase, protease and protein A (By similarity).
What are the official names of this protein?
Conserved virulence factor B.
What is the protein family that this protein belongs to?
Belongs to the CvfB family.
Protein: AROB_ENTFA
Sequence: MKLTVTLPTHSYDLTIETGALDKIGTWVRSLWQPQRVAIITDETVNKLYGAAVEKELQAAGFETSLIAVAAGEQSKSLEIAQLLYDFLAEQQLTRSDGLIALGGGVVGDLAGFVASTYMRGIHFLQVPTTLLAQVDSSIGGKTAVNTKKAKNLVGTFAQPDGVLIDPNTLKTLEPRRVREGIAEIVKSAAIADVELWHRLSSLENEQDLVAHAEEIITACCKIKRDVVEEDELDLGLRLILNFGHTIGHALENTAGYGVIAHGEGVSLGMIQITQVAEQQGLSPLGTTQELVTMLEKFHLPVTTDRWSEERLYQAITHDKKTRGGQIKIIVLEKIGQAKIVSLPTEEIRAFLNREGGI
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGT_ALKCK
Sequence: MEEQIEPIDRVFVQLGPIAIYWYAVLILLGVAVGYFMARRESVKRGLPQETFADLLVWALPISILSARAYYVIFRWEQFADNPISVFYLREGGIAIHGALIGAVVTAIVFAKKRGLSFWKLADVAAPSILIGQAIGRWGNFVNQEVYGAEVTREFLEGMFLPDWIINQMYINGTYYQPTFLYESLWNVLGVVVLLLLRKANLRQGELFLSYVIWYSVGRFVIEGMRLDYLLIGDSLRTAQLLSIILVVAAIALWVYRRLWVKPPRYLNPDAATKQRK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NADE_SHEPC
Sequence: MKAQILREMKVLKAIEPEFEVQRRVAFIKTKLKEARSKALVLGISGGVDSSTAGRLCQLAVDSLNSEQANSDYQFIAVRLPYHIQKDEHEAQLACQFIQPSKLVTVNVHQGVDAVHGATLAAFVEAGLTLPDAAKVDFVKGNVKARMRMIAQYELAGLVGGLVVGTDHSAENITGFYTKWGDGACDLAPLFGLNKRQVRQLAAYLGAPESLVYKAPTADLEDNQPLLEDEVALGLTYAQIDDFLEGKEVDKSVETKLINIYKATQHKRQPIATIYD
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: CY113_POSPM
Sequence: MFLQIAACFTVIGLLYGLVSNLQQNRRLAASLPPGPPGHWLFGNVPPKNFPFIRFAELTEIYGPVFTLRFGRRIVCVVGRHQAAVDILVKHSAETTDRPRAIAASEMLSQGFRILMTPAGERLKKYRRAFHTCLQPSAAATYKPIQYNHAKNYILDCLHDGKCHLEHGRRYAASVVMYIGYGKTTPTSYSDPEVQEVNKCLGRLSEVIKPGAYLVDTYPILKHIPGYASHLWRYGREELALYTRQANAVRKQLEKDEAQPSFAAYLIENQERLGLSNDELAYLSGAIFGAGSDTTAAAIAVMTMAAACYPETQARVQAQLDEVVGSDRAPTFEDEEMLPEVTAFVLEVYRWRPVSAGGVPHRSTKDIVWNGYVIPKGTEIIGNLWAIGRDPELFPDAEEFRPQRWLNENGRIRDDLKYPVFGFGRRVCVGQHVADQSLFINTALALWAFKISQDPAKPIDVLAFTDTANIRPLPFTLRFEPRVKDIEAVLEAHLD
What is the function of this protein?
Cytochrome P450 monooxygenase that is able to use 4-ethoxybenzoic acid as a substrate for oxidation.
What are the official names of this protein?
Cytochrome P450 monooxygenase 113.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ATPA2_DINSH
Sequence: MGIQAAEISAILKEQIKNFGQEAEVAEVGRVLSVGDGIARVHGLDNVQAGEMVEFPGGIRGMALNLEIDNVGVVIFGSDRDIKEGDIVKRTKSIVDVPVGDALLGRVVDGLGNPLDGKGPIETTERSIADVKAPGIIPRKSVHEPMATGLKSVDAMIPIGRGQRELIIGDRQTGKTAVALDTILNQKAYNDAAGDDESKKLYCVYVAVGQKRSTVAQLVKKLEETGAIEYSIVVAATASDPAPMQFLAPYAATSMAEFFRDNGRHALIIYDDLSKQAVSYRQMSLLLRRPPGREAYPGDVFYLHSRLLERSAKLGDDHGNGSLTALPIIETQGGDVSAFIPTNVISITDGQIFLETELFYQGIRPAVNTGLSVSRVGSSAQTNAMKSVAGPVKLELAQYREMAAFAQFGSDLDAATQQLLNRGARLTELMKQPQYSPLTNAEIVCVIFAGTKGYLDKIPVGDVGRYEKGLLAHLRGKHKGLLDYITKEDPKIKGEAEDKIRAALDEFAATFA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha 2, ATP synthase F1 sector subunit alpha 2, F-ATPase subunit alpha 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y436_CERS1
Sequence: MGLSLAAYAGAALAEIAGCFAVWAWWRLGASALWLVPGALSLGAFAWLLALTPVEAAGRSYAVYGGVYVAASLLWLWAVEGVRPDRWDMGGAALVLAGAAVILWAPRG
What are the official names of this protein?
UPF0060 membrane protein Rsph17029_0436.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPA_ANASK
Sequence: MEIRADEISRIIREQIKDYGKKVEVAETGSILSQADGVARIYGLAGAAAGELLEFPGGVRGLVLNLEEDNVGAAIMGPYEHIREGDPVKRTGLIAEVPVGEELLGRVVDGLGNPIDGRGPLNAKHHRKIEIKAPGIVKRKSVHEPMQTGLKAIDALVPIGRGQRELILGDRQTGKTAVAIDTILNNKGNNLYCFYVAIGQKQSTVARVVDTLKKYGAMEYTTVISASASDPAPMQYLAPYTGVTMAEYFRDSGRHALIIYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDKEGAGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLESNLFYQGVRPAINVGISVSRVGGSAQIKAMKQVAGSLKLDLAQYRELAAFAQFGSDLDKATQETLARGERLVELLKQGQYAPLPVEKQVIQIYAGTQKDTDGQNWIRAVPTEQVVRYMRELIEFLDARHPGIAKAIAEKKALDDGIRKDLDAALREFAGIFKIEG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYK_BUCBP
Sequence: MLINEEKERREKLNYIKKHGYNFPNDFKPKNNFSDLTQRYKDYTRDQLFSLKICVSVAGRMTNKRIMGKSSFFILKDFEGEIQLYIQENLFALNFYKQFVKKWDLGDILGAKGKLFKTRTGELSIHCTEIKLLTKALKPLPSKFHGLSDQETRYRQRYLDLISNRTLCSIFKIRSLIFINIRKYMLKKKFLEVETPMMQNIPGGASARPFITHHNTLEIDLYLRISPELYLKRLIVGGFNKIFEINKSFRNEGISTRHNPEFTMMEVYMAYSNYHDMMNFTEKLLMFLVKEIVGNSQVKHGTNIIDFKKKFFRCTLKEAILKYNPSIRLSDLNDEVKMNKIVKKLGINVKKKLNAGQLILEIFNKTVEKKLIQPTFILDYPVEVSPLSRRSDVNKNVVDRFELFISGYEIGNGFSELNDADDQKKRFLMQCKLSHNINNLNKISSFDKHILYDSDYITALEYGLPPTSGLGIGIDRLTMLLTNQKSIRDVIFFPILKPSV
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WAC2C_HUMAN
Sequence: MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHEIKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQDSSGLAPFKTKEPSTRIGKIQANLAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKSSSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ
What is the function of this protein?
(Microbial infection) Plays a role in fluid-phase endocytosis, a process exploited by vaccinia intracellular mature virus (IMV) to enter cells.  As a result, may facilitate the penetration of IMV into cells.
What are the official names of this protein?
WASH complex subunit 2C, Vaccinia virus penetration factor, VPEF.
What is the protein family that this protein belongs to?
Belongs to the FAM21 family.
What are the subcellular locations of this protein?
Early endosome membrane. Cell membrane. Note=Partially colocalizes with RAB11A, a recycling endosome marker. Associates with lipid raft microdomains on the plasma membrane.
Protein: PCRA_LEUCI
Sequence: MSVETLTNGMNNKQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAHLVQDLNVFPWRILAITFTNKAAREMRERIAALLSEDVARDIWVSTFHALAVRILRRDGEAIGLAKNFTIIDTSAQRTLMKRVINDLNLDTNQYDPRTILGMISNAKNDMLQPRDYAKAADNAFQETVAEVYTAYQAELKRSQSVDFDDLIMLTIDLFQSAPDVLARYQQQFEYLHVDEYQDTNDAQYTIVNLLAQRSKNLAVVGDADQSIYGWRGANMNNILNFEKDYPNAHTVMLEQNYRSTQNILDAANAVINHNNERVPKKLWTENGKGDQITYYRAQTEHDEANFILSNIQQLRETKHMAYSDFAVLYRTNAQSRNIEESLVKANMPYSMVGGHKFYERKEILDIMAYMSLITNPDDNAAFERVVNEPKRGLGATSLTRLRELANRLNVSYMKAIGSIELAPSITTKAASKFLTFAEMMHNLRQQSEFLNVTELTELVMTQSGYRQMLAEKNDPDSQARLENLEEFLSVTKEFDDKYQPEDPESIDPVTDFLGTTALMSDLDDFEEGDGAVTLMTLHAAKGLEFPVVFLIGLKEGIFPLSRAMMDEDLLEEERRLAYVGITRAMKKLFLTNAFSRLLYGRTQANEPSRFIAEISPELLETAYSGLSRDKTQKKTLPFDRKMQRATATTYQATPVTKITNGVTGGDQTSWSTGDKVSHKKWGVGTVISVSGRADDQELKVAFPSEGVKQLLAAFAPIQKVD
What is the function of this protein?
Essential helicase.
What are the official names of this protein?
ATP-dependent DNA helicase PcrA, DNA 3'-5' helicase PcrA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. UvrD subfamily.
Protein: RUVA_MYCS2
Sequence: MIASVRGEVIDIALDHAVIEAAGVGYKVMATPSTLATLRRGTEARLITAMIVREDSMTLYGFVDGDARDLFLTLLGVSGVGPKIALATLAVYDPQALRQALADGDVTALTRVPGIGKRGAERMVLELRDKIGPVSAGGGAAVGGHAIRGPVVEALVGLGFAAKQAEEATDKVLANDPEATTSSALRAALSMLGKK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RL20_STAAE
Sequence: MPRVKGGTVTRARRKKTIKLAKGYFGSKHTLYKVAKQQVMKSGQYAFRDRRQRKRDFRKLWITRINAAARQHEMSYSRLMNGLKKAGIDINRKMLSEIAISDEKAFAQLVTKAKDALK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: MYH8_HUMAN
Sequence: MSASSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKEGGKVTVKTEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKDESGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLFSTYASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE
What is the function of this protein?
Muscle contraction.
What are the official names of this protein?
Myosin-8, Myosin heavy chain 8, Myosin heavy chain, skeletal muscle, perinatal, MyHC-perinatal.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
Protein: VF717_ASFM2
Sequence: MTKLAQWMFEQYVKDLNLKNRGSPSFRKWLTLQPSLLRYSGVMRANAFDILKYGYPMQQSGYTVATLEIHFKNIRSSFANIYWNRDSEEPEYVCCCATYQSHDGEYRYRFVWYQPFIEAYNAIETALDSLETIILNLIAARDLDFVVHIFPYNKGHEDYLASTQLILKIFIATLLMDILRIKDNTLDVHLNSDYIIVMERLWPHIKDAIEQFFEAHKDLLGYLIAFRNGGNFAGSLRPSCGQKIVPLTIREALQINDINLAVWREVFIMQECSDLVINGIAPCFPIFNTWTYLQGINQIFFENTSLQEKFKKDFIARELSKEIIKGQKILNDIEFKKLSLHQIQYMESFLLMSDVAIMITTEYVGYTLQSLPGIISRSSYLSPIVKNILMDEDSFMSLLFDLCYGAYVLHKKENVIHADLHLNNMTYYHFNPTSFTDRNKPGKYTLKVNNPVIAFITGPKVETETYVFKHIDGFGCIIDFSRAIMGPNHAIKLERQYGLAFVNTFYRNQSEHILKVLRYYFPEMLTNRENEIQGVILSNFNFFFNSITAIDFYAIARNLRSMLSLDYLHTSEVKRNVEISQTFLDTCQFLEEKAVEFLFKNLHTVLSGKPVEKTAGDVLLPIVFKKFLYPNIPKNILRSFTVIDVYNYNNIKRYSGKAIQTFPPWAQTKEILTHAEGRTFEDIFPRGELVFKKAYAENNYLDKILQRIREQLANENL
What are the official names of this protein?
Uncharacterized protein C717R, pC717R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus C717R family.
What are the subcellular locations of this protein?
Virion.
Protein: OTX2_MOUSE
Sequence: MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKSSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQRSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL
What is the function of this protein?
Transcription factor probably involved in the development of the brain and the sense organs.  Can bind to the bicoid/BCD target sequence (BTS): 5'-TCTAATCCC-3'.
What are the official names of this protein?
Homeobox protein OTX2, Orthodenticle homolog 2.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family. Bicoid subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: K1B_ACTEQ
Sequence: GCKDNFSANTCKHVKANNNCGSQKYATNCAKTCGKC
What is the function of this protein?
Inhibits voltage-dependent potassium channels (Kv1/KCNA).  Inhibits the binding of 125I-alpha-dendrotoxin to rat synaptosomal membranes (IC(50)=22 nM).
What are the official names of this protein?
Kappa-actitoxin-Aeq4a, Kappa-AITX-Aeq4a, Potassium channel toxin Aek.
What is the protein family that this protein belongs to?
Belongs to the sea anemone type 1 potassium channel toxin family. Type 1b subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: LLDD_SHIDS
Sequence: MIISAASDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSEVALRQRILKNMSDLSLETTLFNEKLSMPVALAPVGLCGMYARRGEVQAAKAADAHGIPFTLSTVSVCPIEEVAPAIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMRRYLQAVTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLGNNFDPSISWKDLEWIRDFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAFLYALATAGQAGVANLLNLIEKEMKVAMTLTGAKSINEITQDSLVQGLGKELPAALAPMAKGNAA
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CYSJ_SHESR
Sequence: MLLKELSSLASPLSQPQVEKLKQLTAELNAVQLAWVSGYLAATANAPGNLAQLAPVSDAQAAQTVTILYGSQTGNGRGIAKALAEKAKAQGYSVNLASMGEYNVRQLKQETLLLLVVSTHGEGEAPDDAIELHKFLASKRAPQLSNLHYSVLALGDSSYEFFCQTGKDFDARLSALGAKALLPLVECDVDYEAAAGQWHADVLTAVKPLIQTTANVVALNDTSSALAASESEFTKQNPYSAEVLVSQKITGRGSDRDVRHVEIDLGESGLCYEVGDALGVWFSNNETLVDEILAGLGLAADTKVTVGNESISLKQALLEKKELTQLYPGLVKAWAELSASPELLALSGDKEQVRQFILHHQFADLVANYQLKADANLDANKLVELLRPLTPRLYSIASSQSEVDTEVHLTVALVEDEHQGQARFGGASHFLASAEEGAEVKVYVEPNKHFRLPEDPQTPVIMIGPGTGVAPFRAFMQERVAQGAEGDSWLFFGNPHFEQDFLYQTEWQQYLKNGDLTRIDVAFSRDQAHKIYVQHRIKEQGQTLWQWLQNGAHLYICGDAERMAKDVHQALLAIAVEFGGLSSEAAEEYFETLRSHKRYQKDVY
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.  The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
What are the official names of this protein?
Sulfite reductase [NADPH] flavoprotein alpha-component, SiR-FP.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.