PharMolix/UniProtQA huggingface dataset:
Protein: ATPA_SHIF8
Sequence: MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFKATQSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TSAD_CORGB
Sequence: MIVLGIESSCDETGVGVVKLDGEGNLEILADSVASSMQEHARFGGVVPEIASRAHLESMVPVMREALRQAGVDKPDAVAATVGPGLAGALLVGASAAKAYAAAWGVPFYAVNHLGGHVAVANLEGETLPHAVALLVSGGHTQLLEVDAVGLPMKELGSTLDDAAGEAYDKVSRLLGLGYPGGPIIDKLARRGNPEAIAFPRGLMKKSDSRHDFSFSGLKTSVARYVEAAERNGEVISVEDVCASFQEAVCDVLTFKAVRACRDVGAKVLLLGGGVAANSRLRELAQERCDKAGIELRVPRFNLCTDNGVMIAALAAQRIHEGAQESPISVGTDPSLSVETPQVF
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPB_ECO81
Sequence: MSRKQLALFEPTLVVQALKEAVKKLNPQAQWRNPVMFIVWIGSLLTTCISIAMASGVMPGNALFSAAISGWLWVTVLFANFAEALAEGRSKAQANSLKGVKKTAFARKLREPKYGAAADKVPADQLRKGDIVLVEAGDIIPCDGEVIEGGASVDESAITGESAPVIRESGGDFASVTGGTRILSDWLVIECSVNPGETFLDRMIAMVEGAQRRKTPNEIALTILLIALTIVFLLATATLWPFSAWGGNAVSVTVLVALLVCLIPTTIGGLLSAIGVAGMSRMLGANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASEFIPAQGVEEKALADAAQLASLADETPEGRSIVILAKQRFNLRERDVQSLHATFVPFTAQSRMSGINIDNRMIRKGSVDAIRRHVEANGGHFPADVDQKVDQVARQGATPLVVVEGSRVLGVIALKDIVKGGIKERFAQLRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQAEGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVHIGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNIMRLHSPDSAILSAVIFNALIIVFLIPLALKGVSYKPLTASAMLRRNLWIYGLGGLLVPFIGIKVIDLLLTICGLV
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNAA_LACH4
Sequence: MFDIEKFWQHFNDEMRARFNEVAYNAWFKNTKPIFYNKNTHELKILVQNPVAKGYWEKNLSSQLIQSAYGYAGIEILPVFQINENNDSPERIVTPEPRYAIQLQQEKRAHKQFTKNLKLNEKYTFDNFVQGEGNKLAAGAALAVADSPGSFYNPLFIFGGVGLGKTHLMQAIGHQMLAERPNAKVVYIQSETFVNDFINSIKNKTQDQFREKYRTCDLLLVDDIQFFAKKEGIQEEFFHTFETLYNDQKQIVMTSDRLPTEIPDLSERLVSRFTWGLQVEITPPDLETRIAILRRKAEAEGLVIDDNTLDYIASQVDTNIRELEGALVKVQAYATIERADINVNLAREALVDLKLVQKNRGLQISKIQEVVANYFQTSTAELKGKKRVRQIVVPRQIAMYLSRELTDASLPKIGQEFGGKDHTTVMHAYDKIDKQIKTDTEIKSAVFDLKQMIEH
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VM3E1_ECHOC
Sequence: MQVLLITISLAVLPYLGSSIILESGIVNDYEVVNPQKVTAMLKGAVKQPEQKYEDTMQYEFKVKGEPVVLHLEKNKGLFSEDYSETHYSPDGREITTNPPVEDHCYYHGRIQNDADSSASISACNGLKGHFKLRGEMYFIEPLKIPDSEAHAVYKYENIEEEDEAPKMCGVKHTNRESDKSIKKASQLNLTPEQQRYLNTPKHIKVAIVADYLIFRKYGRNLFTIRAKIYEILNILNEIYKAFNIHVALVFLEIWSNGDKINLFPAANVTLDLFGKWRERDLMNRKNHDNTQLLTGMNFDGPTAGLGYVGTMCHPQFSAAVVQDHNKINFLVALAMAHELGHNLGMTHDEQFCTCGAKSCIMSATLSCEGSYRFSNCSREENRRYLINKMPQCILIKPSRTDIVSPPVCGNSLVEVGEDCDCGSPGYCRNPCCNAATCKLTPGSQCADGECCDQCRFTRAGTECRPARDECDKADLCTGQSAECPADQFQRNGQPCQNNSGYCYNGICPVMRNQCISLFGSRAIVAEDACFQFNSLGIDYGYCRKENGRKIPCAPEDVKCGRLYCFDNLPEHKNPCQIFYTPRDEDKGMVDPGTKCENGKVCINGKCVDVNTAY
What is the function of this protein?
This metalloproteinase hydrolyzes azocasein, and oxidized insulin B-chain.  Also hydrolyzes the alpha-chain (FGA) and more slowly the beta-chain of fibrinogen (FGB), without affecting the gamma-chain.  Does not cleave fibrin.  Inhibits endothelial cell adhesion to extracellular matrix proteins such as fibrinogen, fibronectin, vitronectin, collagen I, and collagen IV.  Induces apoptosis in vascular endothelial cells (By similarity).
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like Eoc1, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIc sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DAPB_HALHL
Sequence: MSLGIGIIGAGGRMGRMLIEVVHRQPGVHVAAATDRTGGEAVGRDAGELAGQGSLGVPIGDDIPAAVAASDAVIDFSLPEATETVAAACAEAGRPLVLGTTGLGETQREAVHRLAEQVAVMHAANYSTGVTLLTALVEQAARAIGVYSDIEIIEAHHRHKVDAPSGTALRLGEAVADALGRDLSQCAVYGREGHTGERDPQTIGFETIRAGDIVGDHTVLFGGDGERVELTHKASSRTTFASGAVRAAAWVVEQPPGLYDMRDMIGV
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_SHEB2
Sequence: MTSIEPTHTGKKVIVGMSGGVDSSVSAYLLMQQGYQVEGLFMKNWEEDDNNEYCAAAEDLKDAQAVCDKLGIKLHTVNFAAEYWDNVFEYFLAEYKAGRTPNPDIMCNKEIKFKAFLEFADEILDADYIAMGHYVRRRDNSDGSTQMLRGVDGNKDQSYFLYTLSHEQVARSLFPVGELEKHEVREIAKEMGLITHDKKDSTGICFIGERKFTEFLGTYLPAQPGNIETPEGEVIGTHQGLMYHTLGQRKGLGIGGMKNSNDDPWYVVDKDLERNVLIVGQGGHHPRLMSTGMTVNQLHWVDRTGPVDGCHIAVKTRYRQQDVPCTLTYTDEHTLGVVFDEPVAAVTPGQSAVFYDGEVCLGGGIIDQLIRG
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD2_COCIM
Sequence: MAPTKDETVDSLKSIIRDLEARVVQLEQKLVHGEGSSKVNSLADGMRMVLMGPPGAGKGTQAPKIKEKYCICHLATGDMLRSQVQKQTELGKQAKKIMDQGGLVSDDIMVNMIKHELETNQECRNGFILDGFPRTVKQAEKLDEMLNARHQKLQHAVELRIDDELLVSRITGRLIHPASGRSYHKIFNPPKVPMTDDITGEPLIQRSDDNVEALKKRLVTYHSQTAPVVGYYKSTGIWKGIDASQEPGQVWKSLLQVFEKK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.  Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
What are the official names of this protein?
Adenylate kinase, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate kinase cytosolic and mitochondrial, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Mitochondrion intermembrane space. Note=Predominantly mitochondrial.
Protein: YAY8_SCHPO
Sequence: MDPVPSTQTQKWPGKHADLDPEPSLLRYCDGRVHVGSGKLAEKKTLLTGGDSGIGKAAAVMFAREGSDLVISCLPEERDDAEVTRDLIEREGRNCWIWEGKLDKSDNCRDLVDFALKKLGWIDVLVNNIAYQQVAQSIEDIDDEQWDLTFKTNIFSFFWVTKAAISHMKSGSSIVNCSSINAYVGRPDLLDYTSTKGAITAFTRGLSNQYAQHGIRVNAVAPGPIYTPLVSSTFPKEKIELSDQVPLGRMGQPVEVASCYLFLACSDGGYMTGQTLHPNGGTVINN
What are the official names of this protein?
Uncharacterized oxidoreductase C4H3.08.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: LG3BP_HUMAN
Sequence: MTPPRLFWVWLLVAGTQGVNDGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGSGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTNETRSTHTLDLSRELSEALGQIFDSQRGCDLSISVNVQGEDALGFCGHTVILTANLEAQALWKEPGSNVTMSVDAECVPMVRDLLRYFYSRRIDITLSSVKCFHKLASAYGARQLQGYCASLFAILLPQDPSFQMPLDLYAYAVATGDALLEKLCLQFLAWNFEALTQAEAWPSVPTDLLQLLLPRSDLAVPSELALLKAVDTWSWGERASHEEVEGLVEKIRFPMMLPEELFELQFNLSLYWSHEALFQKKTLQALEFHTVPFQLLARYKGLNLTEDTYKPRIYTSPTWSAFVTDSSWSARKSQLVYQSRRGPLVKYSSDYFQAPSDYRYYPYQSFQTPQHPSFLFQDKRVSWSLVYLPTIQSCWNYGFSCSSDELPVLGLTKSGGSDRTIAYENKALMLCEGLFVADVTDFEGWKAAIPSALDTNSSKSTSSFPCPAGHFNGFRTVIRPFYLTNSSGVD
What is the function of this protein?
Promotes integrin-mediated cell adhesion.  May stimulate host defense against viruses and tumor cells.
What are the official names of this protein?
Galectin-3-binding protein, Basement membrane autoantigen p105, Lectin galactoside-binding soluble 3-binding protein, Mac-2-binding protein, MAC2BP, Mac-2 BP, Tumor-associated antigen 90K.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space, extracellular matrix.
Protein: DSTOR_CERSP
Sequence: MTKLSGQELHAELSRRAFLSYTAAVGALGLCGTSLLAQGARAEGLANGEVMSGCHWGVFKARVENGRAVAFEPWDKDPAPSHQLPGVLDSIYSPTRIKYPMVRREFLEKGVNADRSTRGNGDFVRVTWDEALDLVARELKRVQESYGPTGTFGGSYGWKSPGRLHNCQVLMRRALNLAGGFVNSSGDYSTAAAQIIMPHVMGTLEVYEQQTAWPVVVENTDLMVFWAADPMKTNEIGWVIPDHGAYAGMKALKEKGTRVICINPVRTETADYFGADVVSPRPQTDVALMLGMAHTLYSEDLHDKDFLENCTTGFDLFAAYLTGESDGTPKTAEWAAEICGLPAEQIRELARSFVAGRTMLAAGWSIQRMHHGEQAHWMLVTLASMIGQIGLPGGGFGLSYHYSNGGSPTSDGPALGGISDGGKAVEGAAWLSESGATSIPCARVVDMLLNPGGEFQFNGATATYPDVKLAYWAGGNPFAHHQDRNRMLKAWEKLETFIVQDFQWTATARHADIVLPATTSYERNDIESVGDYSNRAILAMKKVVDPLYEARSDYDIFAALAERLGKGAEFTEGRDEMGWISSFYEAAVKQAEFKNVAMPSFEDFWSEGIVEFPITEGANFVRYADFREDPLFNPLGTPSGLIEIYSKNIEKMGYDDCPAHPTWMEPAERLGGAGAKYPLHVVASHPKSRLHSQLNGTSLRDLYAVAGHEPCLINPADAAARGIADGDVLRVFNDRGQILVGAKVSDAVMPGAIQIYEGGWYDPLDPSEEGTLDKYGDVNVLSLDVGTSKLAQGNCGQTILADVEKYAGAPVTVTVFDTPKGA
What is the function of this protein?
Catalyzes the reduction of dimethyl sulfoxide (DMSO) and trimethylamine N-oxide (TMAO) to dimethyl sulfide (DMS) and trimethylamine, respectively.  The terminal DMSO reductase can also use various sulfoxides and N-oxide compounds as terminal electron acceptor in addition to DMSO and TMAO.
What are the official names of this protein?
Dimethyl sulfoxide/trimethylamine N-oxide reductase, DMSO reductase, DMSOR, Me2SO reductase, TMAOR.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: B2I_SICPA
Sequence: WIMGHMVNAIEQVDEFLNLGANAIEFDIDFDENGIAKYTHHGIPCDCGRLCTKSAVFTEYLDNVRQVTSPGDPKFRKELVLLALDLKLQRISSEKAYVAGVDVATKLLDHYWKRGWNGGRAYILLNIPLVEDYEFIKGFKDTLRKEGHEQYNAKVGINFTGNEDLDEIRKVLEKLGEDEHIWQADGITSCFPRGTDRLEKALEKRDTPGYKYISKVYAWTLVRSSIMRRSLRLNVDGVMSNYPDRVVGVLKEKEFADKFRLATYADNPWEKFTSI
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin SpaSicTox-betaIIA2, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRH_STAAR
Sequence: MAQISKYKRVVLKLSGEALAGEKGFGINPVIIKSVAEQVAEVAKMDCEIAVIVGGGNIWRGKTGSDLGMDRGTADYMGMLATVMNALALQDSLEQLDCDTRVLTSIEMKQVAEPYIRRRAIRHLEKKRVVIFAAGIGNPYFSTDTTAALRAAEVEADVILMGKNNVDGVYSADPKVNKDAVKYEHLTHIQMLQEGLQVMDSTASSFCMDNNIPLTVFSIMEEGNIKRAVMGEKIGTLITK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAAA_BOVIN
Sequence: MSFVPVAEDSDFPIHNLPYGVFSTRGNPRPRIGVAIGDQILDLSVIKHLFTGPILSGHQDVFNKPTLNSFMGLGQAAWKEARAFLQNLLSASQARLRDDVELRQRAFTSQASATMYLPATIGDYTDFYSSRHHATNVGVMFRGKENALMPNWLHLPVGYHGRASSVVVSGTPIRRPLGQMRPDDSKPPVYGACKLLDFELEMAFFVGPGNKLGEPIPISKAHEHIFGMVLMNDWSARDIQKWEYVPLGPFLGKSFGTTISPWVVPMDALMPFAVSNPEQDPKPLPYLCHDQPYTFDINLSVALKGEGMSQAATICRSNFKYMYWTMLQQLTHHSVNGCNLQPGDLLASGTISGPEPESFGCMLELSWKGTRAVELGNGQTRKFLLDGDEVIMTGHCQGDGYRIGFGQCAGKVLPALSFA
What are the official names of this protein?
Fumarylacetoacetase, FAA, Beta-diketonase, Fumarylacetoacetate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the FAH family.
Protein: RP3A_RAT
Sequence: MTDTVVNRWMYPGDGPLQSNDKEQLQAGWSVHPGAQTDRQRKQEELTDEEKEIINRVIARAEKMETMEQERIGRLVDRLETMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKKNVCTKCGVETSNNRPHPVWLCKICLEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQPAGEPATQEQPTPESRHPARAPARGDMEDRRAPGQKPGPDLTSAPGRGSHGPPTRRASEARMSTTTRDSEGWDHGHGGGAGDTSRSPGGEQGLRRANSVQASRPAPASMPSPAPPQPVQPGPPGGSRAAPGPGRFPEQSTEAPPSDPGYPGAVAPAREERTGPTGGFQAAPHTAGPYSQAAPARQPPPAEEEEEEANSYDSDQATTLGALEFSLLYDQDNSNLQCTIIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLQYHGITEEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKANQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERIGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNENHVSSD
What is the function of this protein?
Plays an essential role in docking and fusion steps of regulated exocytosis (PubMed:8617225, PubMed:16203731).  At the presynaptic level, RPH3A is recruited by RAB3A to the synaptic vesicle membrane in a GTP-dependent manner where it modulates synaptic vesicle trafficking and calcium-triggered neurotransmitter release (PubMed:8617225).  In the post-synaptic compartment, forms a ternary complex with GRIN2A and DLG4 and regulates NMDA receptor stability (PubMed:26679993).  Also plays a role in the exocytosis of arginine vasopressin hormone (PubMed:29367474).
What are the official names of this protein?
Rabphilin-3A, Exophilin-1.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cell projection, dendritic spine. Postsynaptic cell membrane. Membrane; Peripheral membrane protein.
Protein: LGI2_PANTR
Sequence: MALRRGGCGALGLLLLLLGAACLIPRSAQVRRLARCPATCSCTKESIICVGSSWVPRIVPGDISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGNKFECDCKAKWLYLWLKMTNSTVSDVLCIGPPEYQEKKLNDVTSFDYECTTTDFVVHQTLPYQSVSVDTFNSKNDVYVAIAQPSMENCMVLEWDHIEMNFRSYDNITGQSIVGCKAILIDDQVFVVVAQLFGGSHIYKYDESWTKFVKFQDIEVSRISKPNDIELFQIDDETFFVIADSSKAGLSTVYKWNSKGFYSYQSLHEWFRDTDAEFVDIDGKSHLILSSRSQVPIILQWNKSSKKFVPHGDIPNMEDVLAVKSFRMQNTLYLSLTRFIGDSRVMRWNSKQFVEIQALPSRGAMTLQPFSFKDNHYLALGSDYTFSQIYQWDKEKQLFKKFKEIYVQAPRSFTAVSTDRRDFFFASSFKGKTKIFEHIIVDLSL
What is the function of this protein?
Required for the development of soma-targeting inhibitory GABAergic synapses made by parvalbumin-positive basket cells.
What are the official names of this protein?
Leucine-rich repeat LGI family member 2, Leucine-rich glioma-inactivated protein 2.
What are the subcellular locations of this protein?
Secreted.
Protein: SYR_GLOC7
Sequence: MISLIEQLKTRFIQALKTAFDQDFSDLEGLVVPATNPKFGDYQSNVALSLAKPLKQPPRTIAEQIIKALDISDLCEPPQIAGAGFINLTLKANFLENLLAKIQKDSRLGVEKASPSARVIVDFSSPNIAKEMHVGHLRSTILGDCIARVLEFRGHDVLRLNHVGDWGTQFGMLIAYLREVYPEALTTADALNLGDLVAFYKKAKVRFDEDETFKETARKEVVKLQAGAKDTRHAWQLLCDQSRREFQVIYNILDVNLTERGESFYNPLLPEIVGQLDEEGLLTEDQGAKCVFLEGFTNKEGNPLPLIVQKSDEGYNYATTDLAALKYRIKEDKAERIIYVTDAGQANHFAQVFQVAKKAGIIPENIEVVHVAFGVVKGEDGKKLKTRSGDTIKLKDLIDEAVAYARRDLEKRLAEDDRKESKDFINHVSQVVGISAIKYADLSQNRISDYVFSYDKMLALQGNTAPYMLYAYARIQSISREGNIDFEKLDEKAKVILSEETELALGKYLLQFTEVIEDVEINLLPNRLCEYLYELSKKFNKFYENCPVLKSEDPIKTSRLILCDLTARTLKLGLSLLGIAVVERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFUS_PYRWO
Sequence: MRLMIREFFQKYFIDPIKYNTGYNPVNTLVYAIILGIATLLVYKVLKRLKIEINNAFFRALIPYMIFGAFTRALTDAGVFRELISLFPWDILPGLCNSIFCPFSLT
What are the official names of this protein?
Uncharacterized 12.3 kDa protein in fus 3'region.
Protein: Y2617_HAHCH
Sequence: MTPDRRLISIFRSSKKEEMYVYVDKKQGVGALPEALLQLFGKPQHVFDLLLTKEKPLARADAAEVMSAIDEKGFYLQMPPVQDDYMMDVVRAREQTPAVGRKDLDD
What are the official names of this protein?
YcgL domain-containing protein HCH_02617.
Protein: U79_HHV6H
Sequence: MYAEERGYGSFDNVIQAYEQIISQSLHLKRFEFDNGCFIEFLADSGTCETFSKGWISMIYWTSETDSMGSLTVDIGMDEGKCRTYRARGLLLCSKSITSISQNTEGRERILTVSHENGKLQITFVTIAKVSSEPELRNLGDLKFMEKFEKECRALDRKKHDDEHRKRSGKQKEKRKVEDIDKKKEDEKLKQEEKKRNDEDKRPDKKDEFDEPPKEKRQKSHHETKRNLEEQSHEDGIAPTSTTFVNGAVEGALSPCVSIDNHEDQQHDELDKRVYAQGTNREGLSNEDNYGNFQLNKSLEQLRARLVASSGEVVERSLSKLKERLDYVKDNLIKNVLECADVTVPSKCLSKTKHIEQKKQIVFSDCVRSVPVCEIKPFIDMRVFETETTQNARRVRQRTRTTVGSTDGAIGQQRVISGQNRGRARGRGRGRVPRRRNSNLNNLRTQNSAIVIDDSSETENFENAGSFNEDLLATTILETL
What is the function of this protein?
May be involved in DNA replication.
What are the official names of this protein?
Protein U79/U80.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae U79/UL112 family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: KTHY_ALBFT
Sequence: MTTEGIFISFEGIDGAGKSTHIDALAQAFRAQGRAVTLTREPGGTPLAEKLRVLVLNDAMDAMTEALLVFAARRDHLQQLIEPALARGDVVLCDRFTDATFAYQGAGRGFDLKILSFLERTVQSIQGLEPDFIRNPDLTVWFDLAAAIAAQRLAGARSPDKFEAQPVEFFRRVSDGYLNRMTACPSRFARIEANQTREAVWQDVLHAVQARGWLT
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: HSLO_STRT1
Sequence: MDKLIKTISESGSFRAYALDSTETVRTAQEKHNTLSSSTVALGRTLIANQILAANQKGDSKITVKVIGNGSFGHIISVADTKGHVKGYIQNPGVDIKKTATGEVLVGPFMGQGQFVSIIDYGTGNPYTSSTPLISGEIGEDFAYYLTESEQTPSAVGLNVLLDKEDKVKVAGGFMLQVLPGASEEEIARYEKRIQEMPAISTLLESDDHIEALLNAIYGDEPFKRLSEEELSFECDCSRERFENALLTLGKDELQAIKDEDHGAEIVCQFCQTKYEFSEADLEELIND
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_NITSB
Sequence: MALDSAKKQEIISKFAEHEGDTGSPAVQIALLSERISYLTEHLKEHKKDHSSRLGLLKLVGQRKRLLNYLKRKDYEKYTQVIKELGIRG
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: M8H7_BOMMX
Sequence: MKFKYIVAVSFLIASAYARSEENDEQSLSQRDVLEEESLREIRGIGTKILGGLKTAVKGALKELASTYVNGKRTAEDHEVMKRLEAVMRDLDSLDYPEEASERETRGFNQEEIANLFTKKEKRILGPVIKTIGGVIGGLLKNLG
What is the function of this protein?
Maximin-H7 shows antimicrobial activity against bacteria and against the fungus C. albicans.  Shows strong hemolytic activity (By similarity).
What are the official names of this protein?
Maximins 8/H7.
What is the protein family that this protein belongs to?
Belongs to the bombinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: BRK3_PITNO
Sequence: KPLWRL
What is the function of this protein?
Vasodilator.  May target bradykinin receptors (BDKRB).
What are the official names of this protein?
Bradykinin-related peptide Pnor-3.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-related peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: DTFA_DICDI
Sequence: MKDIEASKKPHTTTVAPPQINFIKNNENIFQPKPISNVTTTTVQPPQIVSPPSPPSPPQTTTIAPPTILPTTKTTTTTTTTTTTTTTVQPPQIVSPPIINNLIIQNNLNTPSLSSTPSPLPNNNNSNENDNDINNLKISKEEYQTQIEIQQQIQRQQILERQQLLQRRNQEQLDLLERHNDYQELINTHQNFVPPNNRFSQQIHVSQLKKQSSQSQLQQQLSSQSLQQIQQKSKQPPPQQQQQQQPPPPPIPLLPQIHQQLKPKQQQEQQQQQEQQQQQTENERINELRRLKRKKEYHNDEYKDDEIYLDNILKGIDIRKLEKLTAVELRKIGKTLGVPMGNNTKGETFQRIKSFIENHKKKKQKYREYQSEKNQQQKSNSKKLVNNSTIYDLPIKDIEHLEQLFWRIFRNIVLFRKIIGNLSRGGFFDQQQQQQQQQQSTMTTTSSSSSPMTSSDDKFFYCYNYIFSKTFKYDQIIHVSWIVDSNYFGLLKYKVSRGDLLVFCNHNTINDGDVNDDEDQNTKYEFCKMFKKIFNSIRSIQDKSFYRDLFTNYSEFIFDRINKRYPIDIYLVGSLAIECNCLVATKLLISEFQFRPVMNHSLQLAIKSGSYKMVKLIVTTIHRQMSLNPNNKPFDIEMFSKINNPSIKIINLLIQLRLFTYSNIINLVIADAKLINDNNENDILQFNKNLKNQIFNYSNLLNSFTFNNNINNNNNNNINNNNNNNNNNNNNNNNNNNNNNSNLSNNTIEYSKIKTKTVFNQFTIKQLINSCKLIVTFDLKNQYQQQYYKRHYEDSDNEEEEEITQASFTINTMAEIEFIETQITKEEKHCFVKKVIQKQLLKDGEKEDYDGIKRLAELYVSLNPHLKVYCNFMYKIIYGNENCYDQDLDDEDLFDYRVTRVFDSNCFKQSLKYGSPGYWIEYKEVEMKYAFLSNKYRNEITPNLLFKYVSPNNLNKQLKFIKKIYNSSIENGNSNGNGNGNGGTVIGGILDRLLLFYLIIENNNLELLSIVIKEFPLISNFCYIAKSNSEIYNLKIPRFIRSIEMLEFCFSNFRDHFYLPQSNSLTADFYGFQNVELLRKYDQLMVLDDMDKGIIVSNKKVRASFDDFHFIFEWGSSLKNYNNYLKMLAYIVEDPYGLYTIVTNEILLLSAILSPTTSSGEPLLNLNIERQLIFQEIISSFSTILEGTELKYYPEQMFQESTHLKRFFDWIFENRSEDLLIGGRCVITQSVQSHMLYRAGRLDIVLRKGYYYDDTNEGSKKIMPVGLALVLDDIGKYGDVVALEKYIRSCIPLMKQQSELLTLLDKDERESRACFSQCQRHFSSLLSKASIYGRINIFQHIFYNHQFIFDKKSLLFARKGFLSKISFKKLILECHYHKQHHILDFIQNVIGLDITPKQIKSN
What is the function of this protein?
Required for correct organization of the actin cytoskeleton and cytokinesis.  Also required for apical sorting of prestalk cells, a prerequisite for formation of the tip at the mound stage and subsequent formation of the fruiting body.  May be required for cell adhesion.
What are the official names of this protein?
Defective in tip formation protein A, Cell surface protein dtfA.
What are the subcellular locations of this protein?
Cell surface. Note=Forms a discrete lattice like arrangement at the cell surface.