PharMolix/UniProtQA huggingface dataset:
Protein: RL13_BRUO2
Sequence: MATFSQKPAEVVKKWVLIDAEGLVVGRLASLVANRLRGKHKATFTPHVDDGDNVIIINADKVVLTGKKYTDKKYYWHTGHPGGIKERTARQILEGRFPERVLEKAIERMIPRGPLGRRQMKNLRVYAGPNHQHEAQQPEVLDVAALNRKNKGNA
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RXLRN_PHYIT
Sequence: MKVSKAIVALAALCMALLAPAAGSKELTNIDGDLNNRHLRQESAELATTPEEIGVKKDSNNPLQRRDQALVSAHRVYDPVSGLACALVGDCMACPTSEKDETFCRETGYRQELDCPRPKDPKDAALLTKPEDEREIRFKACSPADTARPGVEVVKFEVRNVLS
What is the function of this protein?
Effector that enhances P. infestans colonization of Nicotiana benthamiana leaves.
What are the official names of this protein?
RxLR effector protein PITG_13625.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane.
Protein: DIH44_CAMFO
Sequence: MILLGILASTTIIGLTSSAPLSSYERRDVSDNRPKIFLLMDERIPELENEILGNELGSDVTRTKRIGSLSIVNNLDVLRNRVMLELARRKQERDQRQIEENRRFLENIGKRSVPVSDAGKIVRSDKSRNDRNQPLQFNRIEWIEEEDPLFRGSQDDQMTRVQANELRLL
What is the function of this protein?
Regulation of fluid secretion.
What are the official names of this protein?
Diuretic hormone 44, DH(44).
What is the protein family that this protein belongs to?
Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
What are the subcellular locations of this protein?
Secreted.
Protein: FMT_ALBFT
Sequence: MRLIFAGTPEFARVALAQLHAGGHEIALVLTQPDRPAGRGMKLQASAVKQFALDHGLALAQPRSLRLDGKYPEDAAAAREALVAAQADAMVVAAYGLILPQWVLDVPARGCFNIHASLLPRWRGAAPIHRAIEAGDAQTGVTIMQMDAGLDTGAMLQAQAIPIGAGDTTGSLHDRLAELGAQLMLQVLAQAVHGSLQPVAQAAQGVTYAPKIEKHEAAIDWTQPAAVIAQRIRAFNPFPGATAVLNGETLKIWLADVAPGVPPVSKEFGSILAVAPVGIEVVAMKSIVNITQLQRPGGKRLGVAEFLRGFDLQPGMVFERHGS
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: KEX1_PARBA
Sequence: MGFSGSRANTALGAWSKWLTLCLAMTQPFSVTAKSAADYYVHSLPGQPEGPLLKMHAGHIEISPETSGNLFFWHFENRHIADKPRTVVWLNGGPGCSSEDGALMEIGPYRLIDKETLNYTEGSWDEFANLLFVDQPVGTGFSYGSTEHYVHELDEMASQFVTFLEKWFEIFPHYEPDDLYFAGESYAGQYIPYIARAILDRNKKQDVLANNRVWNLKGLLIGNGWISPQHQYPAYLPYVYQEGVVQGGTQEANLIEAKAAKCMKELNVEDTTGTVHIPDCEDILQAILDYTHKGKRCINMYDIRLTDEYSACGMNWPPDLKDVQPYLRRKDVVKALHINEEKQTGWTECAGAVGSSFKARKSKPAVELLPGLLEEGLPILLFSGQKDLICNHIGTEDMIKNMKWSGGTGFELSPGVWAPRQYWTFEGEPAGIYQQARNLTYVLFYNASHMVPFDYPRRTRDMLDKFLGVDITHIGGDPADSRIDGEKGPTTSVGAHPNSTAAAEREKEKLNTAAWKAYYKSGEVALIIVSTAAVVWGIFLWRSRRKHQSSGYRSIYPMLGLNSTGSLGRFSHKHSRGNGDIEAADFDETELDGQPSQAFLSRSSGDGETYAVGEESSDEEDGASDGQQLMFDQSRGEGRS
What is the function of this protein?
Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors.  Promotes cell fusion and is involved in the programmed cell death (By similarity).
What are the official names of this protein?
Pheromone-processing carboxypeptidase KEX1, Carboxypeptidase D.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein.
Protein: ADH6_HUMAN
Sequence: MSTTGQVIRCKAAILWKPGAPFSIEEVEVAPPKAKEVRIKVVATGLCGTEMKVLGSKHLDLLYPTILGHEGAGIVESIGEGVSTVKPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQSKTQLMSDGTSRFTCKGKSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFSTGFGAAINTAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGATECLNPQDLKKPIQEVLFDMTDAGIDFCFEAIGNLDVLAAALASCNESYGVCVVVGVLPASVQLKISGQLFFSGRSLKGSVFGGWKSRQHIPKLVADYMAEKLNLDPLITHTLNLDKINEAVELMKTGKW
What are the official names of this protein?
Alcohol dehydrogenase 6.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Class-V subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGB_JANMA
Sequence: MSTKNLLLELFVEELPPKALKKIGEAFAQTLQASLQTQGLLSADSVLTAFASPRRLGVHLTKVLEQADDKTVMQKLMPAAVGIGADGKATPALLKKLAALGADESAVAGLKRESDGKAEVLFFNSVVTGVMLTDGLQKALEETLGKLPIPKVMAYQLADGWETVNFVRPAHGLVALYGADVLNISVLGLHAGNTTHGHRFEAGIDPVYIRDADSYAKQIATEGAVIASFAERRAEIVRQLASAAAEAGSNLTPIEDEALLDEVTGLVERPNVLIGQFEEAFLEVPQECLILTMKANQKYFPLLDSKGGLSNKFLIVSNIRPADASTVIGGNERVVRPRLADAKFFFDQDRKKTLMSRVAGLDKVVYHNKLGTQGERIARVRAIAQAIAGKLGVDAQQADTAAQLAKADLLTDMVGEFPELQGIMGRYYALHDGLPAAVADAIEDHYKPRFAGDELPRNPVGMVVALADKLETLVGLFSIGQVPTGDKDPFALRRHALGIIRMLIEGKLDIGINDLITAAEKPFNGLSAEHRSALLNFIFDRLANALREQGYSAQEIDAVLALQPQRLADVAERLAAVRAFAALPEAASLAAANKRVGNILKKVEGTVAAQVDTALLKEPAEIALNQTLTTVKPQAEAAFARGDYTASLQALAALRNPVDAFFDGVMVNAEDIALRNNRQGLLATLHQAMNQVADISKLAA
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4741_PSEAB
Sequence: MAAKVEPFWKRKTLAQLDQDEWESLCDGCGLCCLQKLEDEDDGSVYYTRIACKLLDLQSCRCTNYAERIRFVPDCIQLTPAQADEFQWLPPTCGYRLVAEGKDLPLWHHLVCGDPERVHKERISQSGRMLSETQVAEDDWEDYLIFRAG
What are the official names of this protein?
UPF0260 protein PA14_47410.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: CYSD_XANOP
Sequence: MTLPPLSHLDRLEAESIHILREVAAEFRAPVMLYSVGKDSSVLLHLLLKAFAPSRPPIPLLHIDTRWKFREMIAFRDRRAAETGVDLRVHINPDGVAQDVSPISHGAAVHTDIMKTQGLKQALEQGGFDAAIGGARRDEEKSRAKERVFSFRNARHRWDPKNQRPELWNLYNARTKPGESVRVFPLSNWTELDVWLYIYREKIPVVPLYFAAPRPVVARDGAWIMVDDARLPLHPGETPQLRSVRFRTLGCYPLTGAIESSADTLEAVIAEMLVSTSSERQGRMIDHAPGASMEQKKVEGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: Y040_AERPE
Sequence: MSREVVVKVKVPSHYVGDIEREVKLAYAVDLFLRGIVSVERAAELAGMSLYDFLVELRRRRIQAYPYSDEELREELGIE
What are the official names of this protein?
UPF0175 protein APE_0890a.1.
What is the protein family that this protein belongs to?
Belongs to the UPF0175 family.
Protein: YGXA_BACSU
Sequence: MENLLRPIYQERASHPNTLAVIMIERRNKTSSLTDNFDAALLVIVKDADEPVFIKHYEFDHQTASLHVVTDSQIQEWILLGTNRRIIDWIVNGRVLFDRNEYVVELIDRLNTFPFAERKLKIGLEYGKLIRRYVEGKAFFEANQFLDAYNAVVHALHHLARIEVIDRGFHPETTVWSQVRQMEPQVYKLYSELIESHESLEKRLELLFLANDFLIHSKAEIGSAHLFEVMKEKDIWQFGELLQHHDLKHFTQDLGVMLDYLTEKGLINVCQIETKGQAVYHRGYSFKKGVDSDS
What are the official names of this protein?
Uncharacterized protein YgxA.
Protein: YQGH_BACSU
Sequence: MINNRENMSVSERLISSRQNRQLDEVRGRMIVTACALIMIAASVAITIFLGVKGLQSFLVNGVSPIEFLTSLNWNPTDSDPKYGVLPFIFGSFAVTILSALIAAPLGIAGAIFMTEIAPNWGKKVLQPVIELLVGIPSVVYGFIGLTVLVPFIAQFKSSGTGHSLLAGTIVLSVMILPTITSISADAMASLPKSLREGSYALGATRWQTIRKVLVPAAFPTLMTAVVLGMARAFGEALAVQMVIGNTRVLPESPFDTAGTLTTIITLNMGHTTYGSVENNTLWSMGLVLLVMSFLFILLIRYLSSRRKV
What is the function of this protein?
Part of the binding-protein-dependent transport system YqgGHIJK.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Probable ABC transporter permease protein YqgH.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CFM9_MARBU
Sequence: MRVLKFLSLMAMLGCTIGQSGSATPGSLHLLGGPTTTDWYPECALRCWENTKYVTKCSEDQQCLCSDVNYQNSVFQCIYSQCDTVHFGSALHHAIAQCLGTDNEVFFAIPPIPDRDALRRREDEYAAGAKLFGSGSAAGYPTESAAFPVQSANYPTDSVGGPYSPSPTASVPFPYFSLTSVTSPAAKSATTTEATRNTVPASTTAPSPSPQLYTGNASTSRATVSLTVVLTVAAVYLVL
What is the function of this protein?
Appears to function during host infection, and may play a role in suppressing the host immune response.
What are the official names of this protein?
Secreted effector CFEM9, MbCFEM9.
What is the protein family that this protein belongs to?
Belongs to the RBT5 family.
Protein: RS20_BACAN
Sequence: MANIKSAIKRAKLSEERRAHNASIKSDMRSAVKTVEALVTNNDLENAKEAFKTASKKLDKAARKGLIHQNAAARQKSRLAKQVNA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RS12_ALISL
Sequence: MATINQLVRQPRAKQVVKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGALDCAGVNDRKKGRSKYGVKRPKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: PRDM4_HUMAN
Sequence: MHHRMNEMNLSPVGMEQLTSSSVSNALPVSGSHLGLAASPTHSAIPAPGLPVAIPNLGPSLSSLPSALSLMLPMGIGDRGVMCGLPERNYTLPPPPYPHLESSYFRTILPGILSYLADRPPPQYIHPNSINVDGNTALSITNNPSALDPYQSNGNVGLEPGIVSIDSRSVNTHGAQSLHPSDGHEVALDTAITMENVSRVTSPISTDGMAEELTMDGVAGEHSQIPNGSRSHEPLSVDSVSNNLAADAVGHGGVIPMHGNGLELPVVMETDHIASRVNGMSDSALSDSIHTVAMSTNSVSVALSTSHNLASLESVSLHEVGLSLEPVAVSSITQEVAMGTGHVDVSSDSLSFVSPSLQMEDSNSNKENMATLFTIWCTLCDRAYPSDCPEHGPVTFVPDTPIESRARLSLPKQLVLRQSIVGAEVGVWTGETIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLEFCIITTDENECNWMMFVRKARNREEQNLVAYPHDGKIFFCTSQDIPPENELLFYYSRDYAQQIGVPEHPDVHLCNCGKECNSYTEFKAHLTSHIHNHLPTQGHSGSHGPSHSKERKWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDKSFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCDKLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAPEEEEEDDSEEEDLADSVGTEDCRINSAVYSADESLSAHK
What is the function of this protein?
May function as a transcription factor involved in cell differentiation.
What are the official names of this protein?
PR domain zinc finger protein 4, PR domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: GCSP_BRUMB
Sequence: MTEFLPFVARHIGPRHEDERAMLAALGLPSMETLITQAVPASIRLNRALNLPAALSEADALAELGTIMGRNVVKKSFIGAGYHGVHTPPVIQRNLFENPAWYTAYTPYQSEISQGRLELLFHFQTLVAELTGLPVACASLLDEATAVAEAIGVACRHHRDKRSRILLAGELHPQTVDVVNTRAEPLGWEIATGSDVDDNTAAIVVPWPDTRGVYGDFAKVIADAKAKGALVIAVADPLALTIMEAPARWGADMAVGSMQRYGVPMGFGGPHAAYLAVSEALTRIIPGRIVGQSVDAHGRAAYRLALQTREQHIRRDKATSNICTAQALLANMAAAFAIWHGPAGLQAIATRVAALAARFAAALKAAGVEIAGESLFDTVTAKVPGKAAAIAAEADKGGRLIRIIDADTVGVTFDETSTEEDLTALASLFGAKPVGGDTVLVPGKERGEGFLTQEVFHSHRSETEMMRFLRRLADKDLALDRAMIPLGSCTMKLNAAAEMMPVSWNTVANLHPFAPAEQVQGYAKMTSDLEAWLCEITGFAGVSLQPNAGSQGEYAGLMAIRHYHQARGQGHRNICLIPSSAHGTNPASASMAGMSVVVVNCRPDGDIDIDDLKAKAEKHRDNLAAFMITYPSTYGVFEEGIKAFCEIVHDNGGQVYFDGANLNALVGLARPADIGADVCHMNLHKTFCIPHGGGGPGVGPIGVAKHLVPYLPGHVEAGSEHAVAAAQFGSASILVITWMYIRMMGGAGLKKATEAAILNANYIAHRLKGVYPILYTGAHDRVAHECIVDTRVLKDSAGITVEDVAKRLIDYGFHAPTMSWPVAGTLMIEPTESEPKLEIDRLCDAMIAIAGEAKKVADGVWPADDNPLANAPHTASDTLATEWKHPYTREEAVFPGGAFDPTAKYWPPVSRVDNVGGDRNLICSCPPVAAYG
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: RS15_MYCGA
Sequence: MALSKDKKTEIIKKFQKNDADVGSVFVQVAVLTEEIKLLTEHLLKNKKDFISKRGLYTKVSKRKNLLNYLKQNDLNAYRNLISELELRHS
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: THIC_CLOBJ
Sequence: MNYTTQMDAAKKGIVTKEMEIVAKKENMNVKDLMELVSKGKVAIPANKNHKSLDPEGIGQGLRTKINVNLGISKDCYNIDMELEKVQKAIDMKAEAIMDLSCFGKTEEFRKRLIDMSPAIIGTVPIYDAVGFYDKELKDITSEEFLKVAEKHAENGADFLTIHVGMNRKTAATFKKNPRTMNIVSRGGSLLYAWMELNNKENPFYEGFDKLLDICEKYDVTLSLGDACRPGCIEDSTDASQIEELIALGELTKRAWERNVQVIIEGPGHMTLDEIEINMKIEKKLCHGAPFYVLGPIVTDIAPGYDHITSAIGGAIAATHGADFLCYVTPAEHLRLPNLDDMKEGIIASKIAAHAADLAKGVKGARDWDNAMAKARRDLDWERMFELSIDEEKARRYREESKAKSKDSCTMCGKMCAVRNMNRVTEGKDLNMLRDDD
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: RRF_MICAN
Sequence: MKLAEVQDQMQKTVESTQRAFNTIRTGRANASLLDRIVVEYYGMETPLKSLATISTPDATTIAIQPFDRTSMGAIEKAISLSDVGLTPSNDGQTIRLNIPPLTSDRRKELVKLAAKLAEEGKVAIRNIRRDAIDAIRKREKGHEISEDESRDLQDQVQKSTDKFIAKIEDLLTTKEKDIMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_MYCSJ
Sequence: MATTIEVKTPAGTTDGSVELPAELFDVEANIALMHQVVTAQLAAKRQGTHSTKTRGEVSGGGKKPYRQKGTGRARQGSTRAPQFTGGGTVHGPQPRDYSQRTPKKMIAAALRGALSDRARNGRIHAVTELVEGQTPSTKSAKAFLSTLTERKQVLVVIGRADETSERSVRNLPGVHIISPDQLNTYDVLKADDVVFSVEALNAYINAQTARTEKEGASA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: PR6A1_MOUSE
Sequence: MLSLSQPCFSGTLLMLLASNFLLWKNVAPVPMYASLDEYGEMSIYDLLDHVTILSHNVSELTAEMHRIFMEDVRYKPGRWFSDRYLTACHTSTLTISVSKEGARQMPGVFLVKEMISMLTAWRYPLYHIITELSYMEQAPDEIISRARNIEEKIIVLIEALRGILSKIQPGPPENERYPVWNELASLQSPDEDLRHLTLFNLFQCLVKDSRKIDSSIRLLKCKLLYNRDC
What are the official names of this protein?
Prolactin-6A1, Placental prolactin-like protein B, PLP-B, PRL-like protein B.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CH602_RHOBA
Sequence: MAKQLLFEDHARARMLAGVEKLAKAVATTMGPTGRNVIIDKSFGGPTVTKDGVTVAKEIELEDRFENMGAKLVIEVAQKTSDLAGDGTTTATVLARAIFKEGLRNIVAGSNPTAIRRGIEKAVEAACDQLVEMGRPVSGKQEVAHVGAISANNDNVIGELLADALERVGKDGVITVEEGKSRNTEVEYVDGMQFDKGYVSPYFITDSSTMEASLEDALVLLYEKKVSNIRDLVPLLEKTAQTGQPLLIIAEDVDAEALTLLVVNKLRGTLNVCAVKAPGFGDRRKAMLGDIATLTGGTLISEDLGMQLENVTLEHLGRAKKVTVDKSNTTIVEGAGKREDIDKRVAQIRAQIEQTDSDYDKEKFQERLAKLAGGVAVISVGAETEAEMKQTKARLEDALHATRAAVEEGILPGGGVALVHCREAVEAAKKKAKGDEKIGVDIVLGALDAPMRQIADNGGIDGSVVVDEVLQKNDPKIGFNAHTGEYTDMVKAGVIDPVKVVRTALTNAASIAGLLLTTEALVTNFEQEDKDKRPVEGMVS
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUS3_MOUSE
Sequence: MAENTDRNQIEKLLNRVKELEQEVERLKKKKEQANNIKDSSIRENSLGSGKAKRAFDFSAHGRRHVALKIAYLGWGYQGFASQENTSNTIEEKLFEALTKTRLVESRQTSNYHRCGRTDKGVSAFGQVISLDLRSQFPTSRDSEDSNLKHEADDLAKEIRYTHILNRVLPADIRVLAWAPVEPSFSARFSCLERTYRYFFPRADLDIATMNYAAQKYVGTHDFRNLCKMDVANGVINFQRTILCAQVQLVAQSPGEERRQEPFQLCQFEVIGQAFLYHQVRCMMAILFLIGQGMEKPEIIDELLNIQKNPQKPQYSMAVEFPLVLYDCKFENTKWIYDHEVQEFNVTHLQQLWANHAVKTHMLYSMLQGLDSVMVTCAAGTKMDEATEWRNIQPPVIKHTSAFVEGVKMRTYKPLMDRPKCQGLESRIRHFVSRGRIEHPHLLHKEEIKARRDCADKEENTVVENPSKRVCIIDAEINSIA
What is the function of this protein?
Formation of pseudouridine at position 39 in the anticodon stem and loop of transfer RNAs.  Also acts on position 38, but much less efficiently.
What are the official names of this protein?
tRNA pseudouridine(38/39) synthase, tRNA pseudouridine synthase 3, tRNA pseudouridylate synthase 3, tRNA-uridine isomerase 3.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DAPD_BURCM
Sequence: MSQQLQQIIDTAWENRAELSPKAAPADVREAVAHALEQLDKGALRVAEKIDGNWTVHQWLKKAVLLSFRLEDNAPMPAGGYSQFYDKVPSKFANYTAEDFAAGGFRVVPPAIARRGSFIAKNVVLMPSYTNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPVIIEDNCFIGARSEVVEGVIVEENSVISMGVYLGQSTKIYDRETGEVSYGRIPAGSVVVAGNLPSKDGSHSLYCAVIVKKVDAKTRAKVGLNELLRGD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDH_HELPJ
Sequence: MKKAGFLFLAAMAIIVVSLNAKDPNVLRKIVFEKCLPNYEKNQNPSPCIEVKPDAGYVVLKDINGPLQYLLMPTTHISGIENPLLLDPSTPNFFYLSWQARDFMSKKYGKPIPDYAISLTINSKKGRSQNHFHIHISCISLDVRKQLDNNLKNINSRWSPLSGGLNGHKYLARRVTESELAQKSPFVMLAKEVPNAHKRMGDYGLAVVQQSDNSFVLLATQFNPLTLNRASAEEIQDHECAILR
What are the official names of this protein?
CDP-diacylglycerol pyrophosphatase, CDP-diacylglycerol phosphatidylhydrolase, CDP-diglyceride hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Cdh family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RL30_SODGM
Sequence: MAQTIKITQTRSSIGRLPKHKATLVGLGLRRIGHTVEREDTPAVRGMVNLVSYMVKVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: HIS1_ECO24
Sequence: MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFGGCRLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMEESKQQLIDKLLTRIQGVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQQRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_HAES1
Sequence: MPAQIISGTELSKNIKFNVAEKIQHYLQQGKRAPGLAVILVGADPASQVYVGSKRRSCEELGIYSKSYDLPAETTEQELLTLIEQLNQDPQIDGILVQLPLPKKINSTKVIEHISPTKDIDGFHPYNVGRLCQRIPTLRACTPLGIMKLLETTGVDLYGQHAVIVGASNIVGRPMALELLLAGCTVTVTHRFTKDLKSHVHQADILVVAVGKPHIIPGEWIKEGAIVIDVGINRVDGKLVGDVQYDEASKKASFITPVPGGVGPMTVAMLMFNTLLAYESHS
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: EFG_WIGBR
Sequence: MPRLTPIVNYRNIGISAHIDAGKTTTTERILFYTGVNHKLGEVHHGSATMDWMAQEQERGITITSAATTCFWSGMSNQFSSHRINIIDTPGHVDFTIEVERSMRILDGAIMVYCAVGGVQPQSETVWRQANKYNVPRIAFINKMDRTGANYFNVINQIKDKLYANPIPIQLPIGKENNFVGIIDLIKMKSIYWSEIDQGITFEYKEIPKDLMVLSNSYRNILLETSAEASEKLTEKYLYKNLTEQDIIEGLRIRSLKNEIIPVTCGSAFKNKGIQSMLDTVINYLPSPKDIKYSKKNKFLSKNYKKSILPKDNEPFSALAFKIANDPFVGNLTFFRVYSGKIRSGNTVLNSAKDKQERFGRIVQMHANKREEIKEVRSGDIAAAIGLKDVTTGDTLCDPLHPIILEKMEFPEPVISVAVEPKTKSDQEKMSSALNRLAKEDPSFRVSSDEESGQTIISGMGELHLEILIDRMYREFNVRSNVGKPQVSYRETIKSCVEEEGKFIRQSGGRGQFGHVWLRIEPNKSNIAKNKNNYTFINKIVGGAIPKEFIPAIDKGIQEQLSNGVLAGYPIVDVCVTVFDGSYHEVDSSEIAFKIAASIAFKSAFMKASPILLEPIMKVEVETPNEYMGDVIGDLNRRRGIIDGMQDINMGKIIISKIPLSEMFGYATDLRSQTQGRASYSMEFLRYNELPNNITESIINSNQLK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_HALSA
Sequence: MSSQQIRLATRGSDLALRQAGEVVDTLEDRRHDVELVEVETEGDRVTDALISDLGKTGAFVRALDQEVMEGTVDAAVHSMKDVPTEVPEDLVVAAVPHRENPADVLVTPDGTDLEDLPAGSVVGTASLRRGAQVQAHRPGLDVEPIRGNVGTRVEKLLAPALHREHERRTEAEKEAQSRDAREQRRGDYTADIEAGVENLDTEDGEEGAADDGDDTASSSEFEQSVTEWFDSLTPLQQSAMERDPDTEYDALVMARVGLERTGLLHHVGIEELSTGTHVPATGQGALCVTARRDSDVVDTLRDALEHVRTRVEVTAERVVLEELGGGCIAPIGVHALVQGDTIRTAVQVFSQDGSEQVGETRELDAEQYATDARELAADLRDRGAADLIEDARTEA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Probable porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.