PharMolix/UniProtQA huggingface dataset:
Protein: TBX22_MOUSE
Sequence: MALSSRAHAFSVEALMGRPSKRKAQDPREEMQPELQEEQFVEEGEEILRSPSRDSQQPEKRLKAESSKTVFSCSDESNSQESLQEESVIQVELQGSDLWKRFHDIGTEMIITKAGRRMFPSVRIKVKGMDPVKQYYVILDVVPVDSKRYRYVYHSSQWMVAGNTDHSCITPRFYVHPDSPCSGENWMRQIISFDRVKLTNNEMDDKGHIILQSMHKYNPRVHVVEQDSRIDLSLIESFPTEGVKTFSFKETEFTTVTAYQNQQITKLKIDRNPFAKGFRDPGRNRGVLDGFLETYPWMPSFSMDFKTFVTDTQSGSSGSSPVTSSGGAPSPLNSLLSPSCSPPMVYIPPSSFGMTYPDAYLHSVNIPFCYRICPTNNWRSQPFVLPTPERLPSFIIPQTLPPLMMEVPVVSSRGIINPNSGLHEDCNGQCLQASHSANQMLYGLQNPGNIFHPNAIAQEAISYPFHPPNGCYRYTISMPPRLENVASHLSENGTSQISFTEGSCDHSHWYPAINHYL
What is the function of this protein?
Probable transcriptional regulator involved in developmental processes.  This is major determinant crucial to palatogenesis.
What are the official names of this protein?
T-box transcription factor TBX22, T-box protein 22.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y303_YERPN
Sequence: MFRWGIIFLIIALIEAALGFGGLAGTAAWAAKVVFVVGIILFLISLFTGRKRL
What are the official names of this protein?
UPF0391 membrane protein YPN_0303.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS12A_SCHPO
Sequence: MSEQGDQIEQVDVVEEVEVEAAAPETVSVEDALKEVLKRALVHDGLARGIREASKALDRRQAHLCVLCESCDQEAYVKLVEALCAESETPLIKVADPKVLGEWAGLCVLDRDGNARKVVGCSCVAVTDYGEDSAALQKLLESFSA
What are the official names of this protein?
40S ribosomal protein S12-A.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS12 family.
Protein: Y1101_VIBCM
Sequence: MNIDVVLLLEQNPILLIFVVLAIGLSFGKIRFGSFQLGNSIGVLITSLIMGHLGFSFTPEALTIGFMLFIYCVGIEAGPNFFGIFFRDGKHYLILSLVVLITATWIAYFGGYYLNLDYGLAAGMMAGALTSTPVLVGAQDALNSGLAAVPRHMDLSLILDNVSVGYAMAYLIGLISMIMFAKLLPKLQKQNLSDSAQQIAQERGLGSQRKVYLPIIRAYRVGPELINWIDGRNLRELGIYRQTGCYIERIRRHGILAHPDGDAILQEGDEIALVGFPDSHARLDPSFRNGKEVFDRNLLDLRISEEEIVVKSDSIAGKRLSDLNLSEYGCFLNRVVRAQIEMPMDLDIVLAKGDVLQVSGEKSKVKGLADKIGFISVHSQMADLLAFCSFFILGILFGLVTMTFGQVSFSLGNAVGLLLSGITLGFLRANHPTFGYVPQGALNMVKDLGLAIFMVGIGLNAGSKMFQHLSEVGVQVIGLAFLVSVVPVVFAYLVGAYILKMNRALLFGAIIGARTCAPAMDVVNEYAKSTIPALGYAGTYAIANILMTLTGTIFILLS
What are the official names of this protein?
Putative transport protein VCM66_1101.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NU4C_SPIOL
Sequence: MNSFPWLTTIVVLPIFAGSLIFLFPHRGNKVIRWYTICISMIELLLMTYVFFYHFQPDDPLIQLVEDYKWINFFDFHWRLGIDGLSIGPILLTGFITTLATLAAWPVTRNSQLFHFLMLAMYSAQIGLFSSRDLLLFFIMWELELIPVYLLLSMWGGKKRLYSATKFILYTAGGSIFLLMGVLGVGLYGSNEPTLNLETLVNQSYPVALEIIFYIGFFIAFAVKLPIIPLHTWLPDTHGEAHYSTCMLLAGILLKMGAYGLVRINMELLPHAHSIFSPWLMIIGTMQIIYAASTSPGQRNLKKRIAYSSVSHMGFIIIGISSITDTGLNGAILQIISHGFIGAALFFLAGTSYDRIRLVYLDEMGGIAIPMPKIFTLFSSFSMASLALPGMSGFIAELIVFFGLITSQKYLLIPKLLITFGMAIGMILTPIYLLSMSRQMFYGYKLFNISNSSFFDSGPRELFVSTSIFLPVIGIGVYPDLVLSLSVEKVEAILSNYFYR
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4, chloroplastic, NAD(P)H dehydrogenase, chain 4, NADH-plastoquinone oxidoreductase chain 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: V231_FOWPN
Sequence: MFGNTTISKMLLDYGARIDSRNKEECLPLNHAIATNNKELTSLFLARGADTNIVDKYNRSVLHKAIGNNNITSVKLLLNHGIDYNLRDNHGYTALHYAITLQNREITDMLLSSGADPNIMNNEKHTPLYHALLYRSSNVESLILHGADINIVDDTGKTPLSNTYIDIIDNKNIEVIVSQFTILEYIAPDDIKNQLGYKINTDLINNNKRYSTIKQKCVHEINLLKAIKFHSGYSAEIFLIKSKSNIFHNSQGIQIL
What are the official names of this protein?
Putative ankyrin repeat protein FPV231.
Protein: EFCB3_HUMAN
Sequence: MAVSEIKPKLKLNPLTKVPISHNKRDRDLPGSLQCQLQHKEKKLSASQMAAFQDAYNFFYKDKTGCIDFHGLMCTVAKLGMNLTKHDVYNELKCADIDRDGKVNFSDFIKVLTDKNLFLKAVVPEKETCLDLAGNPGILLFEILSRLLETSALPRKSIIEIVSYFQRKFQHTGPGMLWSPYTMGYGKRTLKPDICTPPSSSMAAFANAARIAIMKEKDLFKFLEELKRCNSGSDSPYSKIPIFPLFPNVDGVVMGKPFKDMQKLEMLRIKEPLHFFEDYFFHKRDWKTQAANIKSMDPASGYSNNIFTIDQMLKKKQTCTVADATAIKQHVKRATDTYNLGIALEHRKEMLNLWQKIRGDLIGMDSRNESFYDTFSTYTWSWNVCQELLSPKDLRLYDAYVNRNSSHNSRSSSSSDTSECYTDSGRKRKRKGLKGFQQ
What are the official names of this protein?
EF-hand calcium-binding domain-containing protein 3.
Protein: ISPD_THET2
Sequence: MEVSVLIPAAGNGLRLGRGPKAFLQVGGRTLLEWTLAAFRDAAEVLVALPPGAEPPKGLGAVFLEGGATRQASVARLLEAASLPLVLVHDVARPFVSRGLVARVLEAAQRSGAAVPVLPVPDTLMAPEGEAYGRVVPREAFRLVQTPQGFFTALLREAHAYARRKGLEASDDAQLVQALGYPVALVEGEATAFKITHPQDLVLAEALARVWSA
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: RK16_TRICV
Sequence: MLSPKRTKYRKYHRGRMRGKATRGNEVTFGDYGLQALEPTWITSRQIEAARRTITRYTKRGAALWIRIFPDKTVTARAAESRMGSGKGAVDYWVAVVKPGTILFEIASVPEEIAATALHLASYKLPIKTKFITRIKI
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ISPH_ECO24
Sequence: MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRYVVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKVHMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEKLSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVLVVGSKNSSNSNRLAELAQRMGKRAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQNVVARLQQLGGGEAIPLEGREENIVFEVPKELRVDIREVD
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: RIMP_METC4
Sequence: MAEPTEKRLVSETGVAARVAQIVEGPIEGLGFRLVRVKISNTNGRTVQIMAERPDGTMGVDECEAVSRAISPILDLEDPVGDAYYLEVSSPGIDRPLVRVSDFERWAGYEAKVELAVPMDGRKRFRGIIGVPSADGTTVPIDLPDVKPGLPSRIDVPLRDLGEAHLVLTDELIRESLRRGSAPPQDGEEGDEEEGAEAEHEAPQVRFIPQPKRPKPKLDKKSDKPVKAKKPKPGGGIVTKAARLKNRDTLH
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_POLAQ
Sequence: MPHSKHPSSHPHIIIYTDGACKGNPGPGGWGAVLRSGSHEKHIHGGEKLTTNNRMEICAVIFALKALKQRSSVELWTDSQYVQKGVTEWLEGWKKRGWKTASKDPVKNADLWQELDTLLPDHDISWHWVRGHNGHPGNELADALANKGVEEFLP
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUI1_ARCFU
Sequence: MSEICPVCGLPKDLCVCEEVAKEQQFIVIKTGKRRYGKEVTIIEGIDKGEINLEELAKYLKSKLACGGTVKNGVIELQGNHVNRVKELLIKKGFNPERIKT
What are the official names of this protein?
Protein translation factor SUI1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SUI1 family.
Protein: RL9_SHEDO
Sequence: MNVILLDKIANLGSLGDQVSVKAGYARNFLLPFGKAVVANAANVEVFEARRAELEAKLAAELATATARAEKLAALEAVVIASKAGDEGKLFGSIGNRDIADAVTAAGVELAKSEVRLPLGALRTTGNFEVEVQVHTEVKAVVKVTVVAEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: ASSY_BRUA4
Sequence: MSKWKDVKKVVLAYSGGLDTSIILKWLQTELGAEVVTFTADLGQGEELEPARKKAEMLGIKEIFIEDVREEFVRDFVFPMFRANAVYEGVYLLGTSIARPLISKHLIEIARKTGADAIAHGATGKGNDQVRFELSAYALNPDIKIIAPWRDWSFKSRTHLLEFAEQHQIPVAKDKKGEAPFSVDANLLHSSSEGKVLEDPAVEAPEYVHMRTISPETAPDKATIIKIGFEKGDAVSINGERLSPATLLAKLNDYGRDNGIGRLDLVENRFVGMKSRGVYETPGGTILLAAHRAIESITLDRGAAHLKDELMPRYAELIYYGFWFSPEREMLQAAIDHSQRHVEGEVTLKLYKGNVMVIGRESDKSLYSDKLVTFEDDQGAYDQKDAAGFIKLNALRLRTLAARDRK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BH153_ARATH
Sequence: MEFSRDAGMMMENKRNVCSLGESSIKRHKSDLSFSSKERKDKVGERISALQQIVSPYGKTDTASVLLDAMHYIEFLHEQVKVLSAPYLQTVPDATQEELEQYSLRNRGLCLVPMENTVGVAQSNGADIWAPVKTPLSPAFSVTSQSPFR
What are the official names of this protein?
Transcription factor bHLH153, BHLH transcription factor alpha, bHLH alpha, Basic helix-loop-helix protein 153, AtbHLH153, bHLH 153, bHLH transcription factor bHLH153.
What is the protein family that this protein belongs to?
Belongs to the bHLH protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS3_CLOAB
Sequence: MGQKVNPHGLRVGVIKEWNAKWYANSKNFSSYLVQDNKIRKFVKNKLSSAGVSRIEIERAAKRVKLNIHTAKPGMVIGKGGQGIEALKKDLVNFVDKENVLINIVEVKNSDANAQLMAENIAQQLERRISFRRAMKQTIQRAMRTGAKGVKTACAGRLAGAEIARTEQYHEGTIPLQTLRADIDYGFAEADTTYGKIGVKVWVYNGEILPTKKIEKKEEANA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RS4_STRSV
Sequence: MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKLSEYGLQLAEKQKLRFTYGVGEKQFRNLFVQASKIKEGILGFNFMLLLERRLDNVVYRLGLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATLGRPAFVSFDAEKLEGSLTRLPERDEINPEINEALIVEFYNKML
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: PEX2_YEAST
Sequence: MSRVAQLDSIALDKELYGQFWSEFNAAFNTSEHKEEWELALNTVVFMCATRFLPHYGSSCTYGSALSGVVFQCRKRTLYVVTVLAGYVWKKITHIIFNGPHCGNQMMWLKLYKWVNLLYHGCDVTNFLRFLAAEGPNARAFLSPLYRAFNVHSTRLIRDGSAIASEFYSNSVFAGLEYQNRQLLWNALLELFSNTLLTKRGLLTFVKKPPRSRSTTTYKTVCPRCGGFPTNPYQIACCRANYCYVCVVKALEWSMCDACGSSGRLTASPVY
What is the function of this protein?
E3 ubiquitin-protein ligase component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling (PubMed:19687296, PubMed:22471590, PubMed:35768507).  The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane (PubMed:35768507).  PEX2 also regulates peroxisome organization by acting as a E3 ubiquitin-protein ligase (PubMed:35768507).  PEX2 ubiquitinates PEX5 during its passage through the retrotranslocation channel: catalyzes monoubiquitination of PEX5 at 'Cys-6', a modification that acts as a signal for PEX5 extraction into the cytosol (PubMed:35768507).
What are the official names of this protein?
Peroxisomal biogenesis factor 2, Peroxin-2.
What is the protein family that this protein belongs to?
Belongs to the pex2/pex10/pex12 family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: SYGA_RHILW
Sequence: MNPKRSFQALILTLHSYWADKGCAVLQPYDMEVGAGTFHPATTLRALGPKPWKAAYVQPSRRPSDGRYGENPNRLQHYYQYQVILKPNPPNLQELYLGSLAAIGLDPLLHDIRFVEDDWESPTLGAWGLGWECWCDGMEVSQFTYFQQVCGIECAPVAGELTYGLERLAMYVQGVDNVYDLNFNGREGDEKISYGDVFLQAEQEYSRHNFEFANTEMLHRHFVDAEKECRALLDAGAPADNANQRLHKCVFPAYDQCIKASHVFNLLDARGVISVTERQSYILRVRTLAKACGEAFLLTDAGGVNLSKEAA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_ALKOO
Sequence: MSKKEKQFVEEITPMEVDFAQWYTDVIKKTDLVDYSPVKGFMVIKPYGYAIWENIQNYMDKRFKETGHKNCYFPLLIPESLLKKEAEHVEGFAPEVAWVTHGGNEELAERLCVRPTSETIICEMYSKWLTSYRDLPFLYNQWCSVVRWEKSTRPFLRTSEFLWQEGHTLHETYEEAQAETLQMLNIYRETAENLLAMPVVIGQKSEKEKFAGAYATYTMEALMHDGKALQAGTSHNLGQHFTTAFDITYSDRNGELKHPYHTSWGVSTRLIGGIIMVHGDNRGLVLPPGIAPTQVVIVPVASHKEGVLDKANELRDRLKDKFRVELDDRDNYSPGWKFNEWEMKGVPIRIEIGPRDIENNQAMLFRRDELEKDAVSLDDLEEAVEKLLEDINNNLLYKAKMMRDEKTYIVKTFDEMKEVMEIKPGFVKAMWCGERACEEHVKAETGVTIRCIPFEQENLGHTCAFCGKEAKHMVYLAKAY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIP8_CANAL
Sequence: MLFLLFLLITPIYAGLIFLTKPSNDPFYNPPKGFEKAAVGDILQSRETPKSITGRFAPLEIQNSWQLLVRSEDSFGNPNAIVTTVIQPFNADPSKVASYQVFEDSAKGDCAPSYALQFGSDLSTLATQAETFLLAPLLEQGYYVVSPDYEGPKSTFTIGKQSGQAVLNSIRAALKSGKITNIKDDAKVVMWGYSGGSLASGWAAALQPSYAPELGGNLLGAALGGFVTNITATAQAADGTVFAGIVANALGGVANEYPEFKSILQSDTDKKSVFDEFDSHCLADGVIDYINTSFLTGDNKIFKTGWDILKSSTIAKIVKDNGLVYQKQLVPKIPIFVYHGSIDQIVPIVNVKKTYQNWCEGGISSLEFAEDGTNGHLTETVVGAPAALTWIIDRFNGKQTVSGCQHDKRLSNFQYPNISSSILKYFKVALDTMMSNGLGSDIQKDKITPDDLRKFLLGGW
What are the official names of this protein?
Lipase 8.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: EIF3M_NEMVE
Sequence: MDTLLPAFIDAEEQEQAQEIRTFLKEQGADLKEESITPLQDELAEILECCQVCFKEDAELESVMNSILSLVLVVPEKRNELIKKCCDKLKANMSEDENSSAAARLRVLSVLFSGLPEKDPMRHEVYCTQLTIAAKASLVDDIPTELELVKGWLGLWDVDADQRRQVFRLLHGALHDEKRSEEASKVMIELLSTYTDENASAAREDAKSCVVSCLTKPNVLIMDNILSLKPVAVLQGDPIYQLLQIFVSGDVQDYKKFYDSNTDFINSIGLSHEMNLKKMRVLTLMSIGKETDEISYEDLATKLGISSDEIEQFLIEAIQTGLVKARLDQVHRKVIISSVAQRTFGINQWQNLHSRLVKWRDNLLSVRGGLQSVVPPITV
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit M, eIF3m.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit M family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGFZ_PHOLL
Sequence: MAYKTPFSSQFPLSSSTLPLTLISLDDWGLVTATGPDTEKYLQGQVTADISALATNQHVLSAHCDAKGKMWSNLRLFHRGESFAYIERRSVLENQLTELKKYAVFSKIALAQDENALLLGVAGKNCRQALSSFFPTLPDADNAVVAHEATTLLHFSLPSERFLLVTNTATAEQLTEKLQAQLNNSEQWLALDIEAGFPIIDAANSTQFIPQATNLQALAGGVCFKKGCYTGQEMVARAKYRGANKRGMYWLAGSASKIPMAGDDLEWQLGDKWRRTGTVLAAVKLNNDNVWIQVVMNNDMESHSVFRVRDDEGHSLTIQPLPYSLNEEK
What is the function of this protein?
Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs.  It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.
What are the official names of this protein?
tRNA-modifying protein YgfZ.
What is the protein family that this protein belongs to?
Belongs to the tRNA-modifying YgfZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGA_MOOTA
Sequence: MNKPLKILLVSPEVAPLAKTGGLADVAGSLPKALAAKGHEVRVAMPRYRQVKEVNYLTDLPVEMDGSLETAVIRQGKLPGEAGIPVYLIDNYKFFYRDGMYGYGDDAARFNFFCKAVLSMLPWLEFQPDIIHCNDWQTGPIPLFLKVKHEDNPFYRETATIYTIHNLQYQGTFPRNILKTMALSEEFFVPERLEFYGQVSYMKAGILYADLVNTVSKKYALEIQTPEYGERLDGLLRKRAADLRGILNGIDYEEFDPATDRRLAVNYDADHLEKKGENKAALQREMELPVRDVPVLGLISRLVSQKGLDLLAAILDPLMQQDLQFVLLGSGEDYYQQLFSRYKVKYRDKMAVKIGFDPVLAQHIYAGCDIFLMPSRFEPCGLGQMISLRYGAVPVVRATGGLEDTIKDLHQYPGVGNGFTFRDYQPQALLDTINRALHVYRHEPGEWRKLMRRGMAADFSWSASAGHYEEMYREALEKRRAAMFKVG
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: TPCA_COCH5
Sequence: MEQLSYQSKLICSDESRHTGCFTTLPIRIHPRDDLADAASRRFVQDWAREMRDGREQSTHFSFSPVGNWSSLIYPEAIPERLGVLAYLSDLGLIHDDGGEGLSIEDAQAEHGELCAALDPSDISSAAPGSRAMKTKKLVSQCMLECISLDRELGLKMLAAFRDVWLAISERNSDKEAQTMEEYLKYRSDNGGMLVFWPMLQFSLGMSISEAEEALVQPIIDAATEGLLLANDYFSWEREYRELQSGQSKRIVSAVDLFIRTKGLSIDDAKEEVKRKIIAAERDFCQRRDDLYTNHPNIPLKLKRWIDCAGLAVSGNHYWCSACPRQNAWKDMSSQSLNGAKRKTSHGATIGMHEAPFKKRKDSSFFGSQPSDDEPSLSEVSSYPFYKPSGLALEAPSKYVSDMPSKGVRSTLIEALNTWLHVPSERLDSIMSVINTLHNASLILDDLEDNSPLRRGYPATHILFGHSQSINTANFMFVRAVQEVAQNLSPNALVALLEELKGLYLGQSWDLYWKHNLACPSEAEYVNMIDHKTGGMFRMLLRIMQAESDVTPQPDFHRLTLLFGRFFQIRDDYMNFQDYTAQKGLCEDLDEGKFSYPVVYCLENHPEYRGYFLSMFRQRPTIATVNACPLSGESKQYLTACLKKSGAFNKTIACLTDMERDLEFEINRLEQQTGETNPMLRLCLAKLSVKGIGRIGEVSPSTSK
What is the function of this protein?
Bifunctional terpene synthase; part of the gene cluster that mediates the biosynthesis of terpestacin (PubMed:29185768).  The bifunctional terpene synthase tpcA converts isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) into the sesterterpene preterpestacin I (PubMed:29185768).  The C-terminal prenyltransferase (PT) domain of tpcA catalyzes formation of GFPP, whereas the N-terminal terpene cyclase (TC) domain catalyzes the cyclization of GFPP into preterpestacin I (PubMed:29185768).  The cytochrome P450 monooxygenase tpcB then hydroxylates preterpestacin I to yield 24-hydroxypreterpstacin I (renamed as preterpestacin II) whereas the cytochrome P450 monooxygenase tpcC further hydroxylates preterpestacin II to yield 16,17-dihydroxypreterpestacin II (renamed as preterpestacin III) (PubMed:29417814).  Finally, the FAD-dependent monooxygenase tpcD converts preterpestacin III into terpestacin (PubMed:29417814).
What are the official names of this protein?
Preterpestacin I synthase tpcA, Aspergilol biosynthesis cluster protein tpcA, Bifunctional terpene synthase tpcA, BFTS tpcA, TS tpcA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the FPP/GGPP synthase family.
Protein: MUTL_ACTPJ
Sequence: MNKPLIHILPPQLANQIAAGEVVERPASVVKELVENSLDAGANQIQIDIEKGGAQLIRIRDNGCGIGKQDLALALARHATSKISSLEDLEMILSLGFRGEALASISSVSRLTLTSRPAGQAEAWQAYAQGREMEVEIQPASHPVGTTIEVANLFFNTPARRKFLRTDKTEFTHIDEVVRRIALAKPNIGFTLTHNGKTVRQYRKVQDNSVEQQQRRVAAICGDDFIQNAIHIDWQHGDLHLHGWIGLPNISRPQNDLCYSYVNGRMMRDKTINHAIRQAYEATDMPEGNYPAFVVFLDIDPSQVDVNVHPAKHEVRFHQGRLVHDFILQGVQTALQGQAEIDLTHQVNEPLPSYQRNTNRMAAGGNSFLASQQAVEFTENFAKPTASHMPNYSPRTSGVSKSAQKWYGELVSQPQNQSDNIQDLIEPKANFAPVIFAQEIDEAEPKPTQVVSAAIGHWQPLAIVQNQALLLKAEQQFYLLSLEKLARLRFQTQLTKGESQALLIPLNLSLDEQQTQRWQTLKTPLAELGFAISEKTWQGQIRLSVTQVPRLLREQNLQQILLSLFASQAVDLTEFFAKFAPIPTAYSLAEAVNWLAETEQTAKSELEKLKVAVDFSAFLARC
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: LEUC_ARTS2
Sequence: MAKTLAEKVWDAHVVRKGDGEGANAQPDLLYIDLHLVHEVTSPQAFEGLRLAGRPLRRPDLTIATEDHNTPTLDIDKPIADLTSRTQIQTLRNNCKEFGVRLHSLGDAEQGIVHVVGPQLGLTQPGMTVVCGDSHTSTHGAFGALAMGIGTSEVEHVMATQTLSLKPFKTMAINVEGTLRPGVSAKDIILAVIAKIGTGGGQGYVLEYRGSAIRALSMEARMTICNMSIEAGARAGLVAPDQTTYDYMYGRPHAPQGAEWDAAVEYWNTLRTDDDATFDVEVDLDADTLEPFVTWGTNPGQGVSLSSRVPSPEDFGDENAKAAAERALQYMGLEAGTPMKEIRVDTVFLGSCTNSRMEDLRAAADIIRGRTKDPNIRMLVVPGSARVRLEAEAEGLDKVFKDFGAEWRFAGCSMCLGMNPDQLEVGERCASTSNRNFEGRQGKGGRTHLVSPVVAAATAVRGTLSSPSDLDPAPESAAVSSSAA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: VBHT_BARSR
Sequence: MRKYEGSNDPYTDPETGVMYNLLGIKDQARLERVESAFAYIRSFELGRTSISGKFDLDHMKKIHKKLFGDVYEWAGKTRLVDIVKDNSKFAHYTQIESYAPQITQQLAREQHLRGLDANEFSQRAGYYMGELNALHPFREGNGRTLREFIWQLAREAGYHIDWDRVERQEMTRASIESYYGNSDLMSALIRRNLTEFTVNRRVDVSQGINERVLSHIDIDKEWPQKGFNIAIQTTQQAPYLSSYTDTSNLEEKAQNALRNEQSYVDTFKELNDHLKTIYKDPQAAALKIEQTILAGKGDKLPDILAKAPNKVGELRGSDRLIDKLKSAGKERKAALYNVPLAISTIRRLQSFYKNSYEKHMDKLTREREQLKVEVPSLSQEAVAYMKNVEVGRNNYSKIPENINKEFVQLESALNRRFGKDVIYKRNFNLSKEIASKQTYDKKLVNELQTAIKFLQQRHIQKQNNLAITRTPSKGITR
What is the function of this protein?
Toxic component of type II toxin-antitoxin (TA) system VbhT-VbhA.  Adenylyltransferase involved in virulence by mediating the addition of adenosine 5'-monophosphate (AMP) to specific residue of host GTPases.  The resulting AMPylation affects GTPases, impairing actin assembly in infected cells.
What are the official names of this protein?
Protein adenylyltransferase VbhT, AMPylator VbhT, Toxin VbhT.
Protein: Y4390_BURTA
Sequence: MNSTPDAFQRPAIRALTPLEARVLGVLIEKQHTVPDTYPLSLNALTAGCNQKTARSPVMNVSEAEVLTSIDGLKRLSLASEGSSSRVPRFEHNMNRVLGIPSQAAALLTMLLLRGPQTAAELRLNTARLHGFADISSVEAFLDELAARAPALVVKLPRAPGERESRWMHLLCGDVALDEALAHGVQEDAVPPSEFEALKAEQKALTAELARLRAFVEYMANELGIDADKFTRES
What are the official names of this protein?
UPF0502 protein BTH_II0990.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: GUAA_PSEFS
Sequence: MALDIHAHRILILDFGSQYTQLIARRVREIGVYCELHPFDMDDEAIREFAPKGVILAGGPESVHEANSPRCPQAVFDLGVPVFGICYGMQTMAEQLGGKVEGSELREFGYARVDVVGKSRLLDGIEDHIDADGLFGLDVWMSHGDKVTKMPEDFHILASTPSCPIAGMFSDERRYYGVQFHPEVTHTKQGGRILSRFILDICECEALWTPSKIAEDAIAQVRAQVGTDNVLLGLSGGVDSSVVAALLHKAIGDQLTCVFVDNGLLRLHEGEQVMAMFAENMGVKVIRANAEDQFLNNLAGESDPEKKRKIIGRTFIDVFDAQSNKLDNIKYLAQGTIYPDVIESAGAKSGKAHVIKSHHNVGGLPEEMNLKLVEPLRELFKDEVRRLGLELGLPYDMVYRHPFPGPGLGVRILGEVKKEYADLLRRADHIFIEELRKADWYHKVSQAFVVFQPVKSVGVVGDGRRYAWVVALRAVETIDFMTARWAHLPYELLETVSGRIINEIEGISRVTYDVSSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.