PharMolix/UniProtQA huggingface dataset:
Protein: GP146_XENLA
Sequence: MWSCEDLNYTNSGEEQYLCNEFHLFLFIFSVLYLIICFPVGLCYNVQLVLVNLYNKATMTMPDVYFVNMAIAGLIINAVAPVYLFGPAYTKWSLWSFGNEVYITLLILFNVSSLVIMYSTTLLSLDYYIECALPRTYMSSVYNTKHVCGFIWGGAVLTSFSSLLFYICNHVSTKIIECSKMQNREAADAIMVLIGYVVPIIAVIYALVLILQIRKEATPLDQESGRLDPSVHRLLIATVCTQFILWTPYYVTLLVNTFMDARVKSSNTFYIRIFQFTEGLSNFLAFSSSFVLPLIHRHINKNFSGKLQRLLKRLHCGSQGCTHEHTVVQQVMT
What is the function of this protein?
Orphan receptor.
What are the official names of this protein?
Probable G-protein coupled receptor 146.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MUTL_AERHH
Sequence: MPIRILPPILANQIAAGEVVERPSSVVKELVENSLDAGADRVEIDIDKGGAKLIRIRDNGSGVAKDELVLALSRHATSKVATLDDLEGINSLGFRGEALASISSVSRLTFTSRTAEQSEAWQAQAEGREMSVTIKPAAHPVGTTVEVVDLFFNTPARRKFMRSEKTEFAHIDELVRRIALSRFDVTLILRHNGKVVRQYKAANTVAEQERRLAAVCGSPFMHYALAVESEHSDVRLWGWLATPEGARPQNDLQYTYVNGRMMRDKLINHAIRQAYDELLPADRFAAYVLYIELDPRQVDVNVHPAKHEVRFHQARLIHDFIFQALFTALRQQGAASDEPLAETLVELPVSAPIEYPGQAPRAEWYGAEHNYRAPAREVREGSSTGRAGNYQPPEPPSREAMRGMGSLLTTLPAVQGTPLAEAETAPVAAAVPAKAGAWRALTLVEQAYLLLERDNRLALLSLVRAERLLLRHWLLETWGQGLAAQPLLLPVSFKLPKNLVALVEQQDRLLKRMGLELKSGGRDTMILTRVPALLRQTDLVRLLPELLQLIESGSDSDAGQQAEVLCQWLVEQGISREKVYDFATANRLLTELVADFSDQLANVRMVRPLALASVLAEFADGH
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: MSBA_ALBFT
Sequence: MTKPISLSNRALYARLLSYVRPYWKAVFLAVIGMVGTAATEPVFPAIMKYLLDNGFQAKDARMVWLIPMGIVTLFLVRSVIVYCTGYLMTWISSRLVTDLRRTMFAKLLALPTHHYDEHSAGQMISRLVYDVSNVTDAATSALITLVRESLTAIALIGYLLYLDWKLTLITLAIGPVIAFTVKSFSKRMRAASQKSLQAMRFISHTIEETISAQQVVKIFGGQERQQKQFFEATEQFRRAQMREAIPASAMTPITHIAASVAVAIIAFLALSQSTGQAGASAGSFISFITAMLMLISPVKQLATVNPTIQRGLAASESIFELLDAAQEDDRGKRQLLRSKGEICFDNVSLRYLGAERFALNDISFRITAGQTVALVGASGGGKSTISALIPRFYPVTSGRVLVDGIDINDITLASLRQNIALVSQNVILFNDTVGANIAYGSLQTCSRDDVIRAARAANAWDFIEQLPNGLDTPIGENGAKLSGGQRQRLAIARALLKDAPILILDEATSALDTESERQVQAALAVLMKNRTTLVIAHRLSTIEHADCILVLDQGRIVETGTHAELLRAGSYYANLSRLQG
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL4_PARPJ
Sequence: MELKLLNANGQEGAGVSASDVVFGRDYNEALIHQVVVAYQANARSGNRAQKDREQVKHTTKKPWRQKGTGRARAGMSSSPLWRGGGRIFPNSPEENFSHKVNKKMHRAGLCSIFSQLAREGRISVVDELTLEAPKTKLLAEKFKAMGLDSVLVITDTVDENLYLASRNLAHVAVVEPRYADPLSLIYFKKILITKAAVAQIEELLS
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RIC1_ARATH
Sequence: MATTMKGLLKGLRYITQIFDEEKEQEMQIGFPTDVKHVAHIGSDGPTNTTPSWMNDFKTQEHEKGQVVSRGNSNKYNPQGTNQRGAGLKELLPSNTNEKPKQKTRRKPGGAASPNHNGSPPRKSSGNAASSDEPSKHSRHNRSAHGSTDSSNDQEPSVRRRRGGIPAPDTEVPNQIPDGSAPPRKATSRPRKLKGSSAGGEGSIKKSSKGKPENSVDTTCNDII
What is the function of this protein?
Functions as downstream effector of Rho-related GTP binding proteins of the 'Rho of Plants' (ROPs) family.  Participates in the propagation of ROP GTPase signals in specific cellular responses.  Required for cortical microtubule organization.  Promotes microtubule bundling and formation of well-ordered microtubule arrays in the neck region of pavement cells.  This restricts cell lateral expansion to generate the narrow neck morphology of pavement cells.  Its function is inhibited when it interacts with activated ARAC4/ROP2.  Represses ARAC4/ROP2 activation and antagonizes the RIC4-actin pathway that promotes the assembly of cortical actin microfilaments.  Acts as downstream effector of ARAC3/ROP6 which functions in a signaling pathway that negatively regulates clathrin-mediated endocytosis and internalization of PIN1 and PIN2.  Required for the asymmetric auxin distribution during root gravitropism and vascular patterning.  Positively regulates auxin responses, but negatively regulates ABA responses during lateral root development and primary root elongation.
What are the official names of this protein?
CRIB domain-containing protein RIC1, ROP-interactive CRIB motif-containing protein 1, Target of ROP protein RIC1.
Protein: GATL4_ARATH
Sequence: MASRSLSYTQLLGLLSFILLLVTTTTMAVRVGVILHKPSAPTLPVFREAPAFRNGDQCGTREADQIHIAMTLDTNYLRGTMAAVLSLLQHSTCPENLSFHFLSLPHFENDLFTSIKSTFPYLNFKIYQFDPNLVRSKISKSIRQALDQPLNYARIYLADIIPSSVDRIIYLDSDLVVVDDIEKLWHVEMEGKVVAAPEYCHANFTHYFTRTFWSDPVLVKVLEGKRPCYFNTGVMVVDVNKWRKGMYTQKVEEWMTIQKQKRIYHLGSLPPFLLIFAGDIKAVNHRWNQHGLGGDNFEGRCRTLHPGPISLLHWSGKGKPWLRLDSRKPCIVDHLWAPYDLYRSSRHSLEE
What is the function of this protein?
May be involved in pectin and/or xylans biosynthesis in cell walls.
What are the official names of this protein?
Probable galacturonosyltransferase-like 4, Galactinol synthase 9, AtGolS9, GolS-9.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 8 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: PNCB_CHRSD
Sequence: MLDSLLDNDFYKFTMQSAVIKRFPYARARYAFINRGEHAFPPGFGEQLREAVDAMADLSLSVEEKRFLERTCPYLDPTYLDFLSGFRYDPSEVDIVQQGERFELRIEGLWYRTILWEVPLMALISEIWYRMGDGKRDADAIIDMRTRDKIEHYKRLGLKIAEFGTRRRYSYDVHDRVVASLRHHGGDTFSGSSNVHLAMRHGVKPIGTHAHEWFMFHGARFGFKMANSLALEHWVDVYRGDLGIALTDTFTSATFFDSFDKKFAKLFDGVRHDSGDPLEFAAATIAHYERMGIDPRTKTIIFSDALTPERVERIDAFCRGRITTAFGIGTNFTNDVGVTPMNMVIKMTEARPEGQHWMPVIKLSDVPDKNTGDPDMIELAKRVLALSRRA
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: ETK_ECOLI
Sequence: MTTKNMNTPPGSTQENEIDLLRLVGELWDHRKFIISVTALFTLIAVAYSLLSTPIYQADTLVQVEQKQGNAILSGLSDMIPNSSPESAPEIQLLQSRMILGKTIAELNLRDIVEQKYFPIVGRGWARLTKEKPGELAISWMHIPQLNGQDQQLTLTVGENGHYTLEGEEFTVNGMVGQRLEKDGVALTIADIKAKPGTQFVLSQRTELEAINALQETFTVSERSKESGMLELTMTGDDPQLITRILNSIANNYLQQNIARQAAQDSQSLEFLQRQLPEVRSELDQAEEKLNVYRQQRDSVDLNLEAKAVLEQIVNVDNQLNELTFREAEISQLYKKDHPTYRALLEKRQTLEQERKRLNKRVSAMPSTQQEVLRLSRDVEAGRAVYLQLLNRQQELSISKSSAIGNVRIIDPAVTQPQPVKPKKALNVVLGFILGLFISVGAVLARAMLRRGVEAPEQLEEHGISVYATIPMSEWLDKRTRLRKKNLFSNQQRHRTKNIPFLAVDNPADSAVEAVRALRTSLHFAMMETENNILMITGATPDSGKTFVSSTLAAVIAQSDQKVLFIDADLRRGYSHNLFTVSNEHGLSEYLAGKDELNKVIQHFGKGGFDVITRGQVPPNPSELLMRDRMRQLLEWANDHYDLVIVDTPPMLAVSDAAVVGRSVGTSLLVARFGLNTAKEVSLSMQRLEQAGVNIKGAILNGVIKRASTAYSYGYNYYGYSYSEKE
What are the official names of this protein?
Tyrosine-protein kinase etk.
What is the protein family that this protein belongs to?
Belongs to the etk/wzc family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=When the protein is overexpressed.
Protein: RBLL1_RHOPA
Sequence: MDMSERIIVTYQVAAAPAEIAARAEALAIEQSVECPLAAVTEQQIRDEIVGRVEAIAPIGETRFSVRVSLASATAPAEPGQLLNMLFGNSSIQPDVTLADVELPPAYPAAFGGPKLGISGLRAKLGAPRRALTGSALKPQGLAPEALAGLAHRLALGGVDLIKDDHGIADQAFSPFAARVPAVARAMREACAVRGAAMLYAPHVSGSLDDMRRQLDIVRREGLSVVMLMPMIVGLANFHLIAKEAEGLIVLAHPSLAGAQRIAPDLLLGKLFRLLGADATIFPHYGGRFAYTPETCRALADAARRDWHDLKPCLPVPAGGIAIDRIKELLAFYGTDVMLLIGGSLLAAGEQLTEHAARFTAEVASHGQ
What is the function of this protein?
Unknown.  Probably does not have RuBisCO activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase-like protein 1, RuBisCO-like protein.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type IV subfamily.
Protein: PP1R7_BOVIN
Sequence: MAAERGAGQQQSQEMMEVDRRVESEESGDEEGKKQNSGMVADLSAHSLKDGEERGDEDPEEGQELPVDMETISLDRDAEDVDLNHYRIGKIEGFEVLKKVKTLCLRQNLIKCIENLEGLQSLRELDLYDNQIRRIENLDALTELEVLDISFNLLRNIEGIDKLTRLKKLFLVNNKINKIENISSLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDNNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLDCWSDLDELKGARSLETVYLERNPLQRDPQYRRKIMLALPSVRQIDATFVRF
What is the function of this protein?
Regulatory subunit of protein phosphatase 1.  Inactivates the PPP1CC isoform 2 during epididymal sperm maturation.
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 7, Protein phosphatase 1 regulatory subunit 22.
What is the protein family that this protein belongs to?
Belongs to the SDS22 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DEOB_LEGPC
Sequence: MTGRVCVLVMDSFGIGASLDAARYGDVGANTLVHIYEACKRGECDIDGVRKGSLMLPNLASKGLYHAAMASSGLPFIDLSALAIPSGYYGYAVEQSLGKDTPSGHWEMAGVPVTFEWGYFPDKPYCFPEELISEFIKQCNLPGVLGEKHASGTIIIDELGEEHIRTGKPIVYTSADSVFQIAAHEEAFGLQRLYDICKIARNLVDKYQIGRVIARPFAGKPGSFKRTGNRKDYATPPPEKTLLDFLKEDGREVIAIGKIADIYAHQGVTQEIKADGNMALFDATLSAMKTAPQGSLVFTNFVDFDSSYGHRRDVAGYAHALEQFDARLPELEVLLQPNDMVFIAADHGCDPTFPGSDHTREHIPVLMFGPQVNSKFIGRRDCFADIGQSIAEHLQLSSPLAHGVSFL
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCS1_TRIV2
Sequence: MTTDNSAPTASPWWSLPGKFLRREFLPVLTDLRLAIALLLIIALFSISGTVIEQGQSPAFYQANYPEHPALFGFLTWKVIQVVGLDHVYRTWWFLSLLVLFGTSLTACTFTRQLPALKTAQRWKYYEEPRQFQKLALSAELDAGSVNSLSQILQNRRYKIFQEKDDILYARKGIVGRIGPIIVHIGIVTILLGSIWGAMTGFIAQEMVPSGETFQVKNIIDAGPLAAGQFPQDWSVRVNRFWIDYTPKGGIDQFYSDMSVLDNQGKEVDHKKIFVNQPLRYHGVTFYQTDWGISGVRVRLNKSPIFQLPMALLNTNGQGRIWGTWIPTKPDLSEGVSLLAKDLQGMVLIYDAQGKLVDTVRAGMSTQVNGVTLKVLDVVGSTGLQIKADPGIPIVYTGFGILMLGVVMSYFSHSQIWALQKGDRLYVGGKTNRAQVAFEQEVLEILERLSSQSATASNQQS
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsB.
What is the protein family that this protein belongs to?
Belongs to the Ccs1/CcsB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: PRMA_GEOTN
Sequence: MKWSEISIHTTHEAVEAISNILHEAGAGGVVIEDPYDLVKDRDDWYGEIVELNPDDYPEEGVVIKAYLPVNSFLGETVEQIKQAINNLWLYDIDLGKNKITLSEVNEEEWATAWKKHYHPVKVSEKFTIVPTWETYEPASNDELIIEMDPGMAFGTGTHPTTVMCLQALEKYVHPGDNVIDVGTGSGILSIAAAMLGAHSVRALDLDPVAIDSARLNVKLNKVQHVVTVAQNNLLDHIDEQADVIVANILAEIILRFTADAYRLLKPGGRFITSGIIQAKKQDVKDGLLAAGFFIEEVNVMEDWVAFVAIKP
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DJLA_SHIFL
Sequence: MQYWGKIIGVAVALLMGGGFWGVVLGLLIGHMFDKARSRKMAWFANQRERQALFFATTFEVMGHLTKSKGRVTEADIHIASQLMDRMNLHGASRTAAQNAFRVGKSDNYPLREKMRQFRSVCFGRFDLIRMFLEIQIQAAFADGSLHPNERAVLYVIAEELGISRAQFDQFLRMMQGGAQFGGGYQQQSGGGNWQQAQRGPTLEDACNVLGVKPTDDATTIKRAYRKLMSEHHPDKLVAKGLPPEMMEMAKQKAQEIQQAYELIKQQKGFK
What is the function of this protein?
Regulatory DnaK co-chaperone.  Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway.  The colanic acid capsule may help the bacterium survive conditions outside the host.
What are the official names of this protein?
Co-chaperone protein DjlA.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type III membrane protein.
Protein: RL15_SINMW
Sequence: MKLNEIKDNEGATKNRKRLGRGIGSGSGKTAGRGVKGQKARSGVSINGFEGGQMPIYRRLPKRGFNNIFASEFVVVSLGRIQAAVDAKKLDASKTVDAAALKAAGVIRRVKDGVRVLADGELKAKVSLEVAGASKPAIEKIEKAGGSIKLLSAAAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RL23_HALWD
Sequence: MSSLIEYPLVTEKAMDEMDFDNKLQFIVDTDATKDEIENEIESRYEITIIDTKTQITPRAKKKATVRLSDDDDAQDIASRIGVF
What is the function of this protein?
Binds to 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: ARGE_EDWI9
Sequence: MNTQLPSFIALYRALIATPSISANDGALDQSNERLITLLAGWLSDLGLRVEMQPVPNTRNKFNLLANYGEGAGGLMLAGHTDTVPFDEGRWTRDPFTLSEQDNRLYGLGTADMKGLFAFIIDTLRDIELHKLNKPLYILATADEETSMAGARYFAASTALRPDCCIIGEPTSLKPIRAHKGHLSEAIRITGQSGHSSDPARGVNAIEIMHNAIGHLLTLRNTLQQRYHNPAFNIPYPTMNLGHIHGGDAANRICACCELHLDMRPLPGMTLNDLNELLNQALTPIAAQWSGRLRIEHLHPPIPGYECPRHAPLVQAIEQLLGERAEAVNYCTEAPFLQEVCPTLVLGPGSIEQAHQPDEYLSTDFIVPTRTLLTQLIHHFCQR
What is the function of this protein?
Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids.  Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
What are the official names of this protein?
Acetylornithine deacetylase, AO, Acetylornithinase, N-acetylornithinase, NAO.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. ArgE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S39A6_PONAB
Sequence: MARKLSVILILTFALSVTNPLHELKAAAFPQTTEKISPNWESGINVDLAITTRQYHLQQLFYRYGENNSLSVEGFRKLLQNIGIDKIKRIHIHHDHEHHSDHEHHSDHEHHSDHEHHSHRNHAASGKNKRKALCPDHDSDSSGKDPRNSQGKGAHRSEHASGRRNVKDSVSASEVTSTVYNTVSEGTHFLETIETPRPGKLFPKDVSSSTPPSVTEKSRGSRLAGRKTNESVSEPRKGFMYSRNTNENPQECFNASKLLTSHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQIAWVGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLTLIKQFKDKKKKNQKKPENDDDVEIKKQLSKYESQLSTNEEKVDTDDRTEGYLRADSQEPSHFDSQQPAILEEEEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDDLIHHHHDYHHILHHHHHQNHHPHSHSQRYSREELKDAGIATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVPEMLHNDASDHGCSRWGYFFLQNAGMLLGFGIMLLISIFEHKIVFRINF
What is the function of this protein?
May act as a zinc-influx transporter.
What are the official names of this protein?
Zinc transporter ZIP6, Solute carrier family 39 member 6, Zrt- and Irt-like protein 6, ZIP-6.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MAS11_AGRRH
Sequence: MPLPRAYLGTAQPPASVKEFYFVRHGATDLNEKEMHLQGEKHWGVQGAGTNIGLNGTGKRQAVLAGNVLRKLPIGSVVCSPLLRAIQTALIANIGFLCFDIDEDLKERDFGKHEGGYGPLKMFEDNYPDCEDTEMFSLRVAKALTHAKNENTLFVSHGGVLRVIAALLGVDLTKEHTNNGRVLHFRRGFSHWTVEIHQSPVILVSGSNRGVGKAIAEDLIAHGYRLSLGARKVKDLEVAFGPQDEWLHYARFDAEDHGTMAAWVTAAVEKFGRIDGLVNNAGYGEPVNLDKHVDYQRFHLQWYINCVAPLRMTELCLPHLYETGSGRIVNINSMSGQRVLNPLVGYNMTKHALGGLTKTTQHVGWDRRCAAIDICLGFVATDMSAWTDLIASKDMIQPEDIAKLVREAIERPNRAYVPRSEVMCIKEATR
What is the function of this protein?
Reduces deoxy-fructosyl-glutamine to mannopine.
What are the official names of this protein?
Agropine synthesis reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: MACB1_YERPA
Sequence: MAALLELEGIRRSYQSGEEIVDVLQDVSLTINAGELVAIIGASGSGKSTLMNILGCLDKPSAGIYRVAGQNVDELDDDALAALRREHFGFIFQRYHLLPHLSAAHNVEVPAVYAGLGKHERRERANMLLTRLGLGDRVSYQPNQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSSVEVMAILKQLQQQGHTVIIVTHDPTVAAQAERVIEIKDGRIMADSGSKNEPVVAAAELMSLTPAAPSWQQLVGRFREALLMAWRAMSANKMRTALTMLGIIIGIASVVSILVVGDAAKQLVLADIRAIGTNTIDIYPGKDFGDDDPSTRQALVHDDMAALKAQSYVSAVSPSIGGSMRLRFGNIDVAASVLGVSDEYFRVFGMAMEQGAPITREQVERQAQTVVIDLNTQRRLFPHMKDVVGQVILVGNMPATVVGVVAEKKSMFGSNKALRVWVPYSTMANRLMGRSYFDSITIRIKEGYSSKEAEQQLVRLLTLRHGKKDIFTYNMDSLLQTAEKTTQTMQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARSSDVMQQFLIEAVLVCLIGGALGISLSFAIGLIVEMFLPNWRIAFPPMALFSAFLCSTVIGVVFGYLPARSAARLNPIDALARE
What is the function of this protein?
Part of the tripartite efflux system MacAB-TolC.  MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ADD_SHEPA
Sequence: MNYLQLPKIDLHCHLDGSVRPQTVIDLAKLQDVTIPSFNVDDIKALMVAPASCPNLDEYLTRFALPVSVMQTEAALERISFELFEDAAKENVKYLEVRFGPQLHQKMSLNFEQIIGSVVKGMRRAEAQYDIKGNYILSIIKVLPKDDINDVIDAGAKFLNNGVVAFDLAASEEPGFCHEYIPYAKYALEKGYRITIHAGEQGVGQNVYDAISLLGAERIGHGIHINSHQQAYELVKTEAVALETCPSSNVQTKAVESIESHPFGDFYRDGLLVTINTDNRTVSDTTMTKELQLAAEKFNLTEADYFAIYKMSVDNAFTSDEVKLSLLKFID
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: RS5_STAAS
Sequence: MARREEETKEFEERVVTINRVAKVVKGGRRFRFTALVVVGDKNGRVGFGTGKAQEVPEAIKKAVEAAKKDLVVVPRVEGTTPHTITGRYGSGSVFMKPAAPGTGVIAGGPVRAVLELAGITDILSKSLGSNTPINMVRATIDGLQNLKNAEDVAKLRGKTVEELYN
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: PTH_HUMAN
Sequence: MRPGGFLGAGQRLSRAMSRCVLEPRPPGKRWMVAGLGNPGLPGTRHSVGMAVLGQLARRLGVAESWTRDRHCAADLALAPLGDAQLVLLRPRRLMNANGRSVARAAELFGLTAEEVYLVHDELDKPLGRLALKLGGSARGHNGVRSCISCLNSNAMPRLRVGIGRPAHPEAVQAHVLGCFSPAEQELLPLLLDRATDLILDHIRERSQGPSLGP
What are the official names of this protein?
Probable peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
Protein: PROA_BACSU
Sequence: MSEVSVKAKLAKEAAAEMIMKTTAEKDEALSLIANGLRKELDFLLAENAKDIVNGKENGLTPDIIDRLSLDEKRIRDIADAVELLIDLADPIGDSLETIEKENGLFIEKIRVPLGVVGMIYEARPNVTVDAATLCLKTGNAVVLRGSSSAIHSNKALVSVIYRALEQSALPIHAVQLIEDTSRETAKELFTLNDGLDVLIPRGGKKLIDLVVRESTVPVLETGAGNCHIFIDETAKPQMAEKVVVNAKTQRPSVCNAIESLLIHKAWARQHGKELLDQLENAGVEIRGDELVCELHPSSKQASKEDWETEFLAPVLSVKTVENVQEAVKHIQQYGTNHSEAILTENDKNAVYFQTAVDAAAVYHNASTRFTDGFEFGYGAEIGISTQKLHARGPMGLPALTSTKYIIKGTGQIRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMA_I75A2
Sequence: QDLPGNDNSTATLCLGHHAVPNGTIVKTITDDQIEVTNATELVQSSSTGKICNNPHKILDGRDCTLIDALLGDPHCDVFQDETWDLFVERGNAFSSCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSSACKRGPASGFFSRLNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGVHHPSTNQEQTNLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRGQSGRISIYWTIVKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCVSECITPNGSIPNDKPFQNVNKITYGACPKYVKQNSLKLATGMRNVPEKQTRGLFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIKKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNADVLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEDMGNGCFKIYHKCDNACIESIRNGTYDHDIYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLLCVVLLGFIMWACQRGNIRCNICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: HBB_TUPGL
Sequence: VHLSGEEKAAVTGLWGKVDLEKVGGQSLGSLLIVYPWTQRFFDSFGDLSSPSAVMSNPKVKAHGKKVLTSFSDGLNHLDNLKGTFAKLSELHCDKLHVDPENFRLLGNVLVRVLACNFGPEFTPQVQAAFQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.