PharMolix/UniProtQA huggingface dataset:
Protein: TRMN6_ERWT9
Sequence: MSPYKAILRPNGFTFKQFFIAHDRCAMKVGTDGVLLGAWAPVTSVKRVLDIGSGSGLIALMLAQRTSEPVQIDAVELDEEAATQAQENVAASPWAHRVHVQQADVVEWAQRCEHSYSLIVSNPPYFSPGSQCASPERTTARYTTGLTHEMLLDCAEKLIDEDGFFCVILPASAGSKLLEQALQRGWHLRFRTDIADNDTRPANRVLLALSPQPGERLLDSMTIRGPDRQYSAAHCRLTRDFYLFR
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PC21_PENCR
Sequence: MITVTFFWVGIVLGAIWTFYRVVLYPYRVSPLRTLPQSQRGHWLWNHAFSEFLQPIGQLHAELLLQIPNDGMICLRGLFGAPKILLTSPKSLADVLVHRADDFEKLPGERKILRAVVGDGLVTAEGDVHYQQKRKLLASFTPPKIRALYPVFWKEATALTQQIRRTLTHDGSGIYTGTTDMVYWAPRVSMDMIGAAGFGQSFHSVRDVDSEIIHCYEKAFAIGAGHLLCVFADTLLPRIILQWLPWPRWRQFRQNIDSIQDFCHQWVTDAKATSALGDGIPSNLLANMIHTGEYTFQELIEQVRTFLAAGHENTSSVVMWVMLALASDSELQSRLRQELQASLPEVELDKVDLAILEQLPLLNAVVSETIRLFPPLPIGNRIAIRDTTVMNHPIPKGTPFLIVPRAINRSSELWGPDADRFNADRWINPDTGRFNNHGGASSNYSFLSFFHGPHNCIGQNFARAELRTVVAAVIRSFDMVLDNPAADVSPVGWFTPRPADGVKVKLRSLV
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the indole diterpenes penitrems (PubMed:26213965).  The geranylgeranyl diphosphate (GGPP) synthase penG catalyzes the first step in penitrem biosynthesis via conversion of farnesyl pyrophosphate and isopentyl pyrophosphate into geranylgeranyl pyrophosphate (GGPP) (Probable).  Condensation of indole-3-glycerol phosphate with GGPP by the prenyl transferase penC then forms 3-geranylgeranylindole (3-GGI) (Probable).  Epoxidation by the FAD-dependent monooxygenase penM leads to a epoxidized-GGI that is substrate of the terpene cyclase penB for cyclization to yield paspaline (Probable).  Paspaline is subsequently converted to 13-desoxypaxilline by the cytochrome P450 monooxygenase penP, the latter being then converted to paxilline by the cytochrome P450 monooxygenase penQ (PubMed:26213965).  Paxilline is converted to beta-paxitriol via C-10 ketoreduction by the short-chain dehydrogenase PC-15 which can be monoprenylated at the C-20 by the indole diterpene prenyltransferase penD (Probable).  A two-step elimination (acetylation and elimination) process performed by the O-acetyltransferase PC-16 and the P. simplicissimum ptmI-ortholog not yet identified in P. crustosum, leads to the production of the prenylated form of penijanthine (Probable).  The FAD-linked oxidoreductase ptmO then converts the prenylated form of penijanthine into PC-M5 which is in turn transformed into PC-M4 by the aromatic dimethylallyltransferase PC-22 (Probable).  A series of oxidation steps involving 4 cytochrome P450 monooxygenases (PC-21, PC-05, PC-23, PC-20) and a FAD-dependent monooxygenase (PC-14) are required for the transformation of PC-M4 to penitrems A and E.  Synthesis of these final products is proposed to proceed via penitrems D and C (PC-21, PC-05, PC-14) and penitrems B and F (PC-21, PC-05, PC-14, PC-23) (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase PC-21, Penitrem biosynthesis cluster protein PC-21.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL2_ACIBS
Sequence: MPIQKCKPTSPGRRFVEKVVHDHLHKGAPYAPLVEAKKRTGGRNNNGHITTRHVGGGHKQHYRIVDFKRNKDGVPAVVERIEYDPNRTAHIALLKYADGERRYIIAPKGLRAGDKVQSGNDAPIRPGNCLPLRNMPIGSTLHNVELKIGKGAQLARSAGASVQLLGRDGSYAIIRLRSGEMRKVHVECRAVIGEVSNQENNLRSLGKAGAARWRGVRPTVRGMAMNPIDHPHGGGEGRNKGIQPVSPWGQKAKGYKTRTNKRTTKMIIRDRRVK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: P2XB_DICDI
Sequence: MTIDWDSILSYNTIKVVRIRDRRLGILHLCFLIVIVLYVVVYSAIIKKGYVTTEEPVGSIRTSLLAPDELKSNQAYCKNNTEPYPYEKLDCVYYDEKLALFPIGDDVGFTASTRMRISDQTVNCSLMNPSCKFYTNTSMNVYLADIESFTVLIDHTMYAPSSQIQFNGDDLSGYVLDQNGNEIQLNESVNTIGVQGKPDILQLGKLLEFAGVDLDGPSLVNSSNSIRYDGCVLFVFIEYSNTFSYDLKKIKYVYSIKKVDDTAYDVPEVIILNNENSRLYYKRHAIRLIFIQTGVIGSFNFQSLLLTLVSGLGLLTVSTLIVDQLAIRFLPQRKSYSSLKFQTTESFRMKKKIVNDDGEDKLYHNIEAL
What is the function of this protein?
P2X receptors are ATP-gated ion channels that play a role in intracellular calcium signaling.  Not required for the purinergic response to extracellular nucleotides.  Not essential for osmoregulation.  Inward currents are evoked by intracellular ATP and ATP analogs.  Insensitive to the P2 receptor antagonists PPADS and suramin, and also copper ions.  Inhibited by sodium ions.  Permeable to chloride ions.
What are the official names of this protein?
P2X receptor B, P2XB.
What is the protein family that this protein belongs to?
Belongs to the P2X receptor family.
Protein: SEPF_STAA1
Sequence: MSHLALKDLFSGFFVIDDEEEVEVPDKQQQVNEAPAKEQSQQTTKQNAIKSVPQKSASRYTTTSEERNNRMSNYSKNNSRNVVTMNNATPNNASQESSKMCLFEPRVFSDTQDIADELKNRRATLVNLQRIDKVSAKRIIDFLSGTVYAIGGDIQRVGTDIFLCTPDNVEVAGSITDHIENMEHSFD
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: RTCB_ARCFU
Sequence: MNMEGILKKITDYKWELPKSYKPGMRVPAYFYISRKLMQILEKDAVEQAANVATMPGIQVASLVMPDVHVGYGFPIGGVAGFDVNEGVVSPGGVGFDINCGVRLLRSNLNVEDVKPLIKKLIDELFVAVPSGVGSEGRLRVSDRELDEIFVEGARWAVENGYGYERDLKHCEEEGALEGARPEVVSKKARDRGRPQLGTLGSGNHFLEVQYVDKVFDEKVAAKFGIEEGMVTVMIHCGSRGLGHQVCTDFLEVLDRAVKKYGIKLPDRQLACAPINSKEGQDYFAGMAASANYAWCNRQIIAHWVRETFQKVMGMSEDDLGMELVYDVAHNIAKFEEHRVDGKKMKLCVHRKGATRAFGPGLKEVPEDYRDVGQPVLIPGSMGTPSYILVGTEKAMEETFGSTCHGSGRVMSRAAAKRKLRGNVVKQNLERKGIYVRATHGALLAEEAPEAYKLSDDVVDVVHRAGISKLVARLRPLGVAKG
What is the function of this protein?
Essential for tRNA splicing and maturation.  Acts by directly joining spliced tRNA halves to mature-sized tRNAs.  Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends.
What are the official names of this protein?
tRNA-splicing ligase RtcB, 3'-phosphate/5'-hydroxy nucleic acid ligase.
What is the protein family that this protein belongs to?
Belongs to the RtcB family.
Protein: RL24_CORGL
Sequence: MKVHKGDMVLVISGPDKGAKGQVIAAFPKTEKVLVEGVNRIKKHVANSAPERGAESGGIVTQEAPIHVSNVMVIDSDGNPTRVGYRFDENGKKVRVSRRNGKDI
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: GUN_SALTI
Sequence: MMTMLRGWITMIVMLTAINAQAACSWPAWEQFKKDYISQQGRVIDPGDARKITTSEGQSYAMFFALAANDRPAFAQLFNWTQNNLAQGSLREHLPAWLWGQKDPDTWSVLDSNSASDGDIWMAWSLLEAGRLWKETRYTEVGTALLKRIAREEVVNVPGLGSMLLPGKIGFAEANSWRFNPSYLPPQLAQYFSRFGAPWSTLRETNLRLLLETSPKGFSPDWVRYESKQGWQLKAEKTLISSYDAIRVYLWTGMMHDGDPQKARLLARFKPMATLTMKNGVPPEKVDVVSGNAQGTGPVGFSAALLPFLQNRGAQAVQRQRVADHFPGSDAYYNYVLTLFGQGWDQHRFRFTVKGELLPDWGQECVSSR
What is the function of this protein?
Hydrolyzes carboxymethylcellulose.
What are the official names of this protein?
Endoglucanase, Carboxymethylcellulase, CMCase, Cellulase, Endo-1,4-beta-glucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 8 (cellulase D) family.
What are the subcellular locations of this protein?
Secreted.
Protein: EFTU_SALTO
Sequence: MAKAKFERTKPHVNIGTIGHIDHGKTTLTAAITKVLHDQYPDLNPYMPFDEIDKAPEEKARGITISIAHVEYQTEARHYAHVDCPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTREHVLLARQVGVPYIVVALNKSDMVDDEELLELVELEVRELLSSQEYPGDDLPVVRVSALKALEGDPEWAGKLMELMTAVDTSIPQPEREIEKPFLMPIEDVFTITGRGTVVTGRAERGVLKPNEEVELVGIREKSTKTTCTGIEMFRKLLDEARAGENVGLLLRGVKREDVERGMVVIKPGTATPHTEFEATVYILSKEEGGRHTPFFQNYRPQFYFRTTDVTGVVTLPEGTEMVMPGDNTTMTVKLIQPIAMEDNLKFAIREGGRTVGAGRVTKIIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_BRUSI
Sequence: MTDLRHYDVIVSPVITEKSTMVSEHNQVVFNVARKATKPEIKAAVEALFGVKVTAVNTAVRKGKVKRFCGLVGRQSDVKKAIVTLAEGQSIDVSTGL
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: Y606_STRA5
Sequence: MSQEKLKSKVEQASGSLKEGAGKLTGDKELEAKGFVEKTIAKGKELADDAKDAVEEAVDVVKEKLK
What are the official names of this protein?
UPF0337 protein SAG0606.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: NU4LC_CHLAT
Sequence: MILDSLLILAASVFCIGIYGLITSRNVVRILMSLELLLNAVNINFVAFSNFIDSIEIKGQVISIFIMTIAAAEAAVGLALILAIYRNRDTVDIESFNLLKR
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CA1_CONQU
Sequence: MGMRMMFTMFLLVVLATTVVSINLDHAFDGRNAAANNKATDLMARTVRRFCSDPPCRISNPESCGWEP
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.
What are the official names of this protein?
Putative alpha-conotoxin Qc alphaL-1, QcaL-1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NADA_BURP0
Sequence: MQSAIKSVEYDRPLAAGAACGVGEAWAKVPDALAPDERDALKARIKALLVREKAVLVAHYYVDADLQALADETGGCVADSLEMARFGRDHDAHTLVVAGVRFMGETAKILSPGKRVLMPDLDATCSLDLGCLVDEFSQFCDAHPERTVVVYANTSAAVKARADWMVTSSIGLEIVADLHARGEKIIWAPDRHLGGYIQKKTGADMLMWQGSCLVHDEFKGIELDLLRREYPDAKILVHPESPEGVVALADVVGSTTQLIDAAVKLDAQRFIVATDLGILHKMRLAAPGKTFIEAPTAGNSATCKSCAHCPWMAMNALSNLADVLERGHNEIFVEAAIAQRARMPIDRMLDFAARHKQRVQASGDLQRDQALFANVGAA
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_LACLC
Sequence: MATKKKTNFDDITKKYGAERDKALADALALIEKDFGKGSLMRLGEAANQKVSVVSSGSLALDIALGAGGYPKGRIVEIYGPESSGKTTVALHAVAAVQKEGGIAAFIDAENALDPEYAKALGVNIDELLLSQPDYGEQGLQIAEKLITSGAVDLVVIDSVAALVPKAEIDGEIGDSSVGLQARMMSQAMRKLAGHINKTKTTAIFINQLREKVGVMFGSPETTPGGRALKFYASVRLDVRGSTKIEEGSGDNKTQIGKITKIKVVKNKVAPPFKVALVDIMFGEGISSTGELLNIAVEEGIIKKSGAWFAYNDEKIGQGAEKAKNYLKEHQDVFDEIDHKVRAAHGLLDDSEVAETEEETTASKTKAKAKKEEKXVETEEIELELQD
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAH1_YEAST
Sequence: MSQFEKQKEQGNSLFKQGLYREAVHCYDQLITAQPQNPVGYSNKAMALIKLGEYTQAIQMCQQGLRYTSTAEHVAIRSKLQYRLELAQGAVGSVQIPVVEVDELPEGYDRS
What are the official names of this protein?
TPR repeat-containing protein associated with Hsp90.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SCD2_RAT
Sequence: MPAHILQEISGSYSATTTITAPPSGGQQNGGEKFEKNPHHWGADVRPEIKDDLYDPSYQDEEGPPPKLEYVWRNIVLMALLHIGALYGITLVPSCKVYTCLFAYLYYVISALGITAGAHRLWSHRTYKARLPLRLFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGLLLMCFILPTLVPWYCWGETFVNSLCVSTFLRYAVVLNATWLVNSAAHLYGYRPYDKNISSRENILVSMGAVGEGFHNYHHAFPYDYSASEYRWHINFTTFFIDCMALLGLAYDRKRVSKAAVLARIKRTGEESCKSG
What is the function of this protein?
Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.  Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (PubMed:20228221).  Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids (PubMed:20228221).  Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides, especially during embryonic development and in neonates.  Important for normal permeability barrier function of the skin in neonates.
What are the official names of this protein?
Stearoyl-CoA desaturase 2, Acyl-CoA desaturase 2, Delta(9)-desaturase 2, Delta-9 desaturase 2, Fatty acid desaturase 2.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane.
Protein: LGT_STAAT
Sequence: MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGSVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MALA_STRP1
Sequence: MPDKKQFPISYISHCLSPRAMFASRAQFTWWQNLLIIVFLNALIMIPVTLHYANMTTYPLERIVTKSLSPITDKTYQALTQGKIEKDTFQGQSLIRRDGELVLAVLPTKVDLEQLASESTRQIIVTKKEWRFVTPDGKELRAHVRGQQQSLADLTTVKAVKDFVNQQWYDSNKASVLGFLLLTFVLMVCVGTLIVIGLGAFFLTLTKRSRLFMIRNFSEGLGLMVNCLAWPSLLAIALSFFIQDPVLIMNCQVFGTLLMLTWVFYKTQFRD
What is the function of this protein?
Has a role in maltotetraose utilization.
What are the official names of this protein?
Maltodextrose utilization protein MalA.
Protein: HSP1_PLATE
Sequence: MARCRRHIRSRSRSRNQCQRRRRRSHYNRRRTYRRSRRHSRRRRVRRRGCSCRRCSRRRRRRC
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: NORM_SYNP6
Sequence: MNLRTIRAELQQFLQLAIPLAAAQVAQAAVGFVDTVMMGRLGPEPLAAGGLASALFQFILATASGVVMAVSPLVAEAQGAGKDYKIAAIARQGLWLSVLLGLPVMLIISQLARLMPVLGQSATTIALARDYWMAVLWGIIPGLGFAMLRGYVAALEQARIILPLVLFGTLVNGLGNYLLGYGQLGFPRLELTGLGLSSALGLWVMFLGLLAYTAWQPKLRRYPFWQDWRRLQPSICRQILQLGWAIAVTVAVEFGLFTIITILMGAIGVEALAAHQTVSQTIILIFMVPLGCSFAVTVRVGWWLGRQDGLGARRAGLVGVGAIALWMLLLAIPLALFPRAIVGIYVDLNNPVNAGLLNLALPMLRVASLALVLDGVQRVAMGALHGLQDTRIPLLLSLLAFWMVGVGSSAMLGFQLGWGSTGLWIGQSLGVAIAGGLFLQRFLKLTQNRTFKQRLQPQPLATHP
What is the function of this protein?
Multidrug efflux pump.
What are the official names of this protein?
Probable multidrug resistance protein NorM, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RRF_RICCN
Sequence: MDKEHLKKNLQEKMEKALKVLDHELKGLRTGRASVNLLDSVTVEAYGSKMPLSQVASLSTPDARTINVQVWDKSMVSSVEKGITIANLGLTPATDGQLIRLPIPALTEERRTALVKLAHKYGEDTKISLRNIRRDGNEALKKLEKDNVIAKDEHHSLSEQVQKLTDDYSSKVDSVIKQKEQEIMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DX39A_MOUSE
Sequence: MAEQDVENELLDYDEDEEPQAPQESTPAPPKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQIEPVNGQVSVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEDVLKKNCPHVVVGTPGRILALVRSRSLNLRNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQCMMFSATLSKEIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSEKNRKLFDLLDVLEFNQVVIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAVTFVSDENDAKILNDVQDRFEVNVAELPEEIDISTYIEQSR
What is the function of this protein?
Involved in pre-mRNA splicing.  Required for the export of mRNA out of the nucleus (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DDX39A, DEAD box protein 39.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DECD subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Can translocate to the cytoplasm in the presence of MX1.
Protein: RTC4_YEAS8
Sequence: MVGPGLGINRVRRKGVYSTKKGSGDNLLLMKRQGKHDIHDRESDDLSGHDAFSPSKKRGKIDSITEDEIEVKKLSTVATFDKLSRSFPNSEVQAAKNAALRGKEKEEEKVVSIPLIQNLKNEDIESIKCRNNNLLDGKKLLLEAELSAVEDNQIFSSSFPEDKKLSLQSCLSSKEQIIKKLQVREEYMSKFKLPPMLFSDELLTEVEPFMPIVMDILEGKISSAYYFEAKNAFKNSQKAYLSVDEFRKLNLNKFTAGFYGLKRQLRVGEEIAKRYKRALTHNQPATLKWWGITDFCNYVLAPETLTSFCIYQLNLSNKSCSSKTPNKHPKQQLNEKEYYYDPELRMLAYDLLEDTVEYGIIVADSDPIEQWEAAIEEDRLRELKLDVHNYSSRRWRLDTHD
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 4.
What is the protein family that this protein belongs to?
Belongs to the RTC4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YPB3_LACLL
Sequence: MEVYNLRNTKEKILTATEQLIYKKGYTGTSINDILDETATGKGQFYYYFDSKKEACLAVIDNHVKIWQKHLLNGILSRDESPLANLKEMLDWIYSDHAQKKIYYGCPVGNLVIELSALDEDFRKPLEQLFSDLQKKIAENLSALTGLLVKQNLPAAHAIIAQIQGSLLLLKVTQDLNVLESNFDLLKTSFEKVGEK
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator in lacX 3'region, ORF3.
Protein: YADA_YERPS
Sequence: MTKDFKISVSAALISALFSSPYAFAEEPEDGNDGIPRLSAVQISPNVDPKLGVGLYPAKPILRQENPKLPPRGPQGPEKKRARLAEAIQPQVLGGLDARAKGIHSIAIGATAEAAKPAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGASSTAQKDGVAIGARASASDTGVAVGFNSKVDAQNSVAIGHSSHVAADHGYSIAIGDLSKTDRENSVSIGHESLNRQLTHLAAGTKDNDAVNVAQLKKEMAETLENARKETLAQSNDVLDAAKKHSNSVARTTLETAEEHANKKSAEALVSAKVYADSNSSHTLKTANSYTDVTVSSSTKKAISESNQYTDHKFSQLDNRLDKLDKRVDKGLASSAALNSLFQPYGVGKVNFTAGVGGYRSSQALAIGSGYRVNESVALKAGVAYAGSSNVMYNASFNIEW
What is the function of this protein?
Collagen-binding outer membrane protein forming a fibrillar matrix on the bacterial cell surface.  Promotes attachment to eukaryotic cells and after invasion, is the major adhesin in infected tissue.  Constitutes an alternative uptake pathway under conditions in which invasin synthesis is repressed.
What are the official names of this protein?
Adhesin YadA, Type 5 secretion system autotransporter YadA.
What is the protein family that this protein belongs to?
Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
What are the subcellular locations of this protein?
Cell surface. Cell outer membrane. Note=The C-terminal translocator domain is localized in the outer membrane and the passenger domain is at the cell surface.
Protein: SAR1_HYPJE
Sequence: MWIVNWFYDVLSSLGLLNKHAKLLFLGLDNAGKTTLLHMLKNDRVAILQPTLHPTSEELAIGNVRFNTFDLGGHQQARRIWRDYFPDVNGVVFLVDAKDHERFPEAKAELDALLSMEELSKVPFVILGNKIDHPDAVSEDELRHQLGLYQTTGKGRVQLEGIRPIELFMCSVVMRQGYGDGIRWLSNYV
What is the function of this protein?
Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.  Sar1 controls the coat assembly in a stepwise manner.  Activated sar1-GTP binds to membranes first and recruits the sec23/24 complex.  These sec23/24-SAR1 prebudding intermediates are then collected by the sec13/31 complex as subunits polymerize to form coated transport vesicles.  Conversion to sar1-GDP triggers coat release and recycles COPII subunits (By similarity).
What are the official names of this protein?
Small COPII coat GTPase sar1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. SAR1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: UREF_RUEST
Sequence: MTSEATLKLMQWLSPAYPVGAFAYSHGLEGAVSEGHVRDGDTLSDWLSDLLTHGGARSDALLLACAYRTETAESLAEIDDTARAFCPSAERLQETDLQGAAFCRTTAAIWDTALPSLTYPVAVGHAARLNDVALDLTLNMYLHAFLSNLVAAGQRLLSLGQTEAQQRLNACGPQLRRTVDAALSGTIDDLFGASFAADIASMRHETQYSRIFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.