PharMolix/UniProtQA huggingface dataset:
Protein: RLMD_ALISL
Sequence: MAQFFKPKKKASVNTKHLSVDVVRLDHNSAGIAFVDKKPVFIEGALPEEQAIIQFIEQKKQYSRAKLIKLTKKSSKRQAPICQHYDDCGGCNLQHLQHAEQIIAKNDKLQELMKKQGVDACDVAEPILANEHDYRRRARISLIMNKQTNQLDFGFRKKQSKEIVNVRHCPVLVKELDQHLESLYTLLNQLKGKRHLGHVELVQADNGSVLLIRHVAAFNEKDQQALLHYCEERDLILYLMPESDVLNHVYGEEPYYVIDEVKIYFTPKDFIQVNASINDSMVNQALTWLDLNADDCVLDLFCGLGNFSLPLAQKVKTVVGIEGVEEMVKRAQSNAKRNELDNVTFYQANLEEPIDQQVWASTKFTKILLDPARAGAAGVMQTVAKLKPETVVYVSCNPATLARDSQLLIQRGYKLTRLGMLDMFPHTGHLESMALFER
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: RLME_BUCCC
Sequence: MILKKRSKSSKNWLKRNFNDPYIKERNKKKLRSRSWFKLKEIDESEKIFKKGMNVIDLGSNPGGWSEYTLKKIGKSGKIFACDILPMRFLKDIVFFCGDISNSDFLKKIFLFLDKYSWNVVMSDISPNICGYSVIDNSNMFKLSNIVLKISRHVLSNNGYLIIKLFQGYGFNKYMKKIRNIFELVKIYKPNASRVNSREVFIIAYGCKK
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GNT10_ARATH
Sequence: MGHLPQSLYSAAGPKFPYPGSSGLGVDQRKLTWSRFPVFLRCASTESLTSLTQNNAAEIELKYLVSQHGWDVRRLNRDDEDEIRRVSLVQAEAFHIPLALFDDFFFMFFQAEVLSALLYKLKNSPPDRYACLVAEQTSETETLSSSSVVGVVDVTAQTESSVLRYFPGVEEYLYVSGLAVSKSQRRKKMASTLLKACDVLCYLWGFKLLALRAYEDDAAARNLYSNAGYSVVETDPLWTSTWIGRKRRVLMSKRFS
What is the function of this protein?
Protein acetyltransferase with dual specificity triggering both N-alpha-acetylation (NTA), with a preference for leucine, methionine, serine, valine and to a lower extent threonine and alanine as substrates (can also use glycine), and epsilon-lysine acetylation (KA) of several plastid proteins.
What are the official names of this protein?
GCN5-related N-acetyltransferase 10, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. GNAT subfamily.
Protein: PRMA_PSEPW
Sequence: MPWLQVRLAISPEQAETYEDALLEVGAVSVTFMDAEDQPIFEPDLNTTPLWSHTHLLALFEADADPEQVFAHLRLLTGAELPEHQAEVIEDQDWERSWMDNFQPMRFGRRLWIVPSWHEAPEKDAVNLLLDPGLAFGTGTHPTTALCLEWLDGQQLEGTQVLDFGCGSGILAIAALLLGAREAVGTDIDVQAIEASRDNAQRNGVADEKLALYLPEHMPAMQADVLVANILAGPLVSLAPQLSGLVRPGGLLALSGILAEQGEEVAAAYAADFELDPIVVRDGWVRISGRRR
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HXB8B_DANRE
Sequence: MSSYFVNSLFTKFKGGDSLRSNYYDCPSYTPDLGGRPSVLYGHNTGSAFQHAAQFPDFYHHGTSSFPHASYQQTPCAVAYPGDATGNILGQDGLQKQSFFGAPDSDFTQFGDCNLKVSGIRDDLESAEPCTAQLFPWMRPQATGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKEHNKDKFPSSKAEQEEIERERQEGSQVSEKHTSGEEDSEASSNSK
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-B8b, Homeobox protein Hox-A8.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS6_STAAM
Sequence: MIKKRIIPCLDVKDGRVVKGIQFKGLRDIGNPVDLAIYYNEAGADELVFLDISKTEEGHSLMLEVIEQTASRLFIPLTVGGGIQSLDDITQLLNHGADKVSLNSSALKNPQLIKQASDKFGRQCICIAIDSYYDPERKAHYCCTHGGKKMTNIKVYDWVQQVEQLGAGELLVTSMGHDGMKQGFDIEHLAKIKSLVNIPIIASGGGGNAQHFVELFNQTDVSAGLAASILHDRETTVQSIKEVIRQGGIAVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK36_CUSOB
Sequence: MKKRASVRKICDKCRLIRRGGRILVICSNPRHKQGQG
What are the official names of this protein?
Plastid 50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid.
Protein: EFG_METS4
Sequence: MPRTHAIEDYRNFGIMAHIDAGKTTTTERILYYTGKSHKIGEVHEGAATMDWMEQEQERGITITSAATTCFWRDKRLNIIDTPGHVDFTIEVERSLRVLDGAVCVLDGNQGVEPQTETVWRQADKYDVPRVVFVNKMDKIGADFFKCVADIIDRVAGKPVCLQLPIGSENNFRGVIDLIKMKAIVWSGEALGANFSEEAIPADLAEQAAEYRTKLIEACVEMDDDAMTAYLDGVEPDEDTMRRLVRTAVQRRAFHPVLCGSAFKNKGVQPLLDAVVDYLPSPADRGEIKGIDYKTEEEVVRRPSDAEPFSMLAFKIMDDPHVGTITFCRIYSGKVESGANLLNSTRDKRERVGRMLLMHANNREDIKEAYAGDIVALAGLKDTRTGDTLCDPTKAVILEKMEFPEPVIEIAVEPKSKADQEKLGIALSKLAAEDPSFRVSTDPESGQTILKGMGELHLDIKVDILKRTYKVEANIGQPQVAYREKLTRRTEIDYTHKKQTGGTGQFARVKLVVEPNEPGAGYAFESKIVGGAVPKEYVPGVEKGLNSVLTAGILAGFPVVDIKVELIDGAYHEVDSSALAFEIASRAALREALQKGGSVLLEPVMKVEVVTPEDYTGSVIGDLNSRRGQIQGQDMRGNANVINAMVPLANMFGYVNQLRSFTQGRANFTMQFDHYEEVPRGEAEKVVAKYA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CWC2_CANAL
Sequence: MSRKVSISSLTLSEPMTKPARVQVNPEDIDDLDKTQQVNNHQYNIWYSKSLSDANNKSTTKSKYRVRISTDQGFTKANKNTHICLFFSRGCCYLGSKCQYFHRLPKESDNFKPTQDCFGRDKTANYRDDMDGVGSLNKVNCTLYVGGIHIKPNTEQLLVKNFQEFGTVEKVRVLQGKGCAFVTMKTENQAQFAKEAMQSQSLVEGSNEVLYVRWANEDKNPAAQKQEKKRQQELAYDTVKQLLEQESNKKPRLENGAVNRIETINIDDESEDEGAVEDDEADDDIEETRVNSLSAGVKKNVSTHQANGTPESSSTSDENDHNTILRNSLLKDISRLKKKMVYKREEPYLTNLLVDYSSDEDDD
What is the function of this protein?
Involved in the first step of pre-mRNA splicing.  Required for cell growth and cell cycle control.  Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex.  May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA.  Associates predominantly with U6 snRNAs in assembled active spliceosomes.  Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing factor CWC2.
What is the protein family that this protein belongs to?
Belongs to the RRM CWC2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TTCA2_FRAT1
Sequence: MTKTEKKLRHYITKAIADYKLLDKGDKVMLCLSGGKDSFGLLKVLHGLIEDKTYDIDLHVYTLDQSQPGWDDSQLRKYLDDLGVSYEIETKNTYGVIIDKVPEGKTYCSLCSRLRRGNIYRYAKEHKMDKIILGHHRDDLIQSLLMSILYQGQIKSMPPKFVTQDGENTVIRPMVLVQERDLIEFAKEENFPIIPCNLCGSQENLKRKKVKKLIQDLALENPKVPSNILNSLSNVLPSHLMDKNLLNSLEN
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase 2, Two-thiocytidine biosynthesis protein A 2, tRNA 2-thiocytidine biosynthesis protein TtcA 2.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSRA_SHEWM
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQSEKAGNSSEGGNF
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_YERPG
Sequence: MPIKSSDHSLYALFGGTFDPIHYGHLKPVEALAQQVGLQHIILLPNHVPPHRPQPEANAQQRLKMVELAVAGNPLFSVDSRELLRDSPSFTIETLEALRKERGAEQPLAFIIGQDSLLSLHKWHRWQALLDVCHLLVCARPGYSQSLETPELQQWLESHKVMDPQALSQRPHGAIYLADTPLLDISATDIRRRRHNGESCDDLLPQAVQRYIELQGLYRG
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: NUOC_PARPJ
Sequence: MASKLETLKANLEAAFGGLLLNLSEAIGELTIVVKASDYLNVATRLRDDRSLGFEQCVDLCGVDYQTYAEGAYDGPRFAAVLHLLSVQNNWRLRLRVFAPDDEVPILPSVVEIWNSVNWYEREAFDLYGIVFEGHPDLRRILTDYGFIGHPFRKDFPVSGYVEMRYDPEEKRVVYQPVTIEPREITPRVIREDRYGGLKH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GLCF_ECOLI
Sequence: MQTQLTEEMRQNARALEADSILRACVHCGFCTATCPTYQLLGDELDGPRGRIYLIKQVLEGNEVTLKTQEHLDRCLTCRNCETTCPSGVRYHNLLDIGRDIVEQKVKRPLPERILREGLRQVVPRPAVFRALTQVGLVLRPFLPEQVRAKLPAETVKAKPRPPLRHKRRVLMLEGCAQPTLSPNTNAATARVLDRLGISVMPANEAGCCGAVDYHLNAQEKGLARARNNIDAWWPAIEAGAEAILQTASGCGAFVKEYGQMLKNDALYADKARQVSELAVDLVELLREEPLEKLAIRGDKKLAFHCPCTLQHAQKLNGEVEKVLLRLGFTLTDVPDSHLCCGSAGTYALTHPDLARQLRDNKMNALESGKPEMIVTANIGCQTHLASAGRTSVRHWIEIVEQALEKE
What is the function of this protein?
Component of a complex that catalyzes the oxidation of glycolate to glyoxylate (PubMed:4557653, PubMed:8606183).  Is required for E. coli to grow on glycolate as a sole source of carbon (PubMed:8606183).  Is also able to oxidize D-lactate ((R)-lactate) with a similar rate (PubMed:4557653).  Does not link directly to O(2), and 2,6-dichloroindophenol (DCIP) and phenazine methosulfate (PMS) can act as artificial electron acceptors in vitro, but the physiological molecule that functions as primary electron acceptor during glycolate oxidation is unknown (PubMed:4557653).
What are the official names of this protein?
Glycolate oxidase iron-sulfur subunit, Glycolate dehydrogenase subunit GlcF, Glycolate oxidase subunit GlcF.
What are the subcellular locations of this protein?
Cell inner membrane. Note=Glycolate oxidoreductase activity was shown to be firmly associated with the cytoplasmic membranes (PubMed:2689218). And the GlcF subunit itself could only be detected in the membrane fraction (PubMed:8606183).
Protein: BIOD_BURMA
Sequence: MSAPLSLFVTGTDTEIGKTFVSAALLHGFARAGLRAAAMKPVAAGAYERDGAWRNEDADQLDAAANVALPAAIRTPFLLKAPAAPHIVAAREGVALDIGTIVDAHRRACEMADVIVVEGVGGVRVPLADTRDTADLAVALGLPVVLVVGVRLGCISHALLTAEAIAARGLPLAGWVANRIDPAMPFADDNIDTLRAWLEREHRAPLLGALAHMSPPSPDAASHALDVNLLLNALRAAAPR
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TNDD_ASPFV
Sequence: MSLSGSDSHLAVSPTLAEDMNSSDTSAGLAETPPADEEKRSIVDTGESVVAMNEPHIVDWDGPDDPGNPVNFSRHIKITNVGIVSALTFITPLASSMFAPGVPQLMEEFHSSSRLLAGFVVSVYVLGFAIGPLILAPASELLGRVPIYHICNICFTVFSIACALSTNLGMLIAFRFFQGCFGSAPVTNGGGTIADLIVQEKRGGVIAIYALGPLLGPVIGPVAGGYLAAARGWRWVFWVLAIVGGGCTLASFLFLRETYPMVLLKRKTQRLIQETGNTHLRSKNDNGMSTRQRFVQAIVRPSRILFRSPIVAASSVYVGIVYGYQYLMFSTFTYVFEDQYAFPTSSAGLTFLGTGVGSLLGLFVIGAVSDRILKAKSKPTPEAPSGAMKPEYRLPPLVWGAFFIPAGLFMYGWSAYYRTHWIVPIIGTGLVGIGNIAVFMCITSYLVDAFTIFAASALAANTVVRSILGALLPMAGQSMYDSMGLGWGNSLLGFIAVVCIPIPWAMMRYGERMREAFDGATIFTIFSGSVSVTRSTFT
What is the function of this protein?
MFS-type transporter; part of the gene cluster that mediates the biosynthesis of talaronoid C, a fusicoccane diterpenoid with an unprecedented tricyclic 5/8/6 ring system.
What are the official names of this protein?
MFS-type transporter tndD, Talaronoid C biosynthesis cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
Protein: PAND_CHRVO
Sequence: MQRNMLKSKLHRVTTTHAELHYIGSCAIDENLLEAADILEYEEVQIWNVTNGERFATYAIKAERGSGVISVNGSAARRAAPGDLLIIASFAQYEDAELKGHSPKLVFVDGDNRLTEVKGATPTQPA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBA5_DROPS
Sequence: MTNAIDELQAIIAELKTEVEEQRAVIRQSRDRIEHMSAEVVDSNPYSRLMALQRMNIVKNYERIRDKTVAIVGVGGVGSVTADMLTRCGIGKLILFDYDKVELANMNRLFFTPDQAGLSKVEAAARTLTFINPDVRIETHNYNITTIDNFDNFLSTITGDGTVAGEPVDLVLSCVDNFEARMAINAACNEKCLNWFESGVSENAVSGHIQFLRPGDTACFACAPPLVVAENIDEKTLKREGVCAASLPTTMGITAGFLVQNALKYLLNFGEVSDYLGYNALNDFFPKMTLKPNPQCDDRNCLLRQKEFQARPKPVVVQEEAPTDEPLHASNDWGIELVAEDAPSDAPTDLSQSTDVGQGLRLAYEAPEKSSAEATQAATAPVDDTSLEDLMAQMKSM
What is the function of this protein?
E1-like enzyme which activates UFM1.
What are the official names of this protein?
Ubiquitin-like modifier-activating enzyme 5, Ubiquitin-activating enzyme 5.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.
Protein: RL36_MYCS5
Sequence: MKVRSGVKKICKKCTIIKRKGVNRVICEIPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: DEFL_STAEQ
Sequence: MTVKKLVKSTHPILNKTIQPVSTYDQKLKVLLEDLEDTLYHEEAAAISAPQIGVDQSVALIDMEQEGLLQLINPVVKSQSQETVSDLEGSISLPHIYGEVKRSKMITVQSYDINGNAVELTAYDDIARMILHMIDHLNGIQFTKRAHHILNETEVEAYFDNE
What are the official names of this protein?
Peptide deformylase-like, Polypeptide deformylase-like.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: LMBD1_BOTFB
Sequence: MALIQTAFIWVAYAVAVGIVALIAAIFTYTYQTPRDRSALVSTVTIITLTSLLATVLLLPVDIALVSSTTSKLGAKKDWATPETVHNILLTLKIVYYALYSFDAVLCLLVIPFTYFFYEEYDEIDSEEGTQTFGQRFLSAAKYTLFFVALVVILFLVGFFVPVAKNRGSDMDLDYFKRLLAENHGERALTFALGLLISLGTLLYILYTSVGLALLPISFIKSAPSISAPQLSETTASALEQNRERQRQLEGRNAGRDGGLSAKDQRELEALHREERTLVRRERLAAESRGDGKSFIVRAWTKTCAIFRPLKLIGGILLLILSLIIWVSMLITGIDKAKNSFCKQHCGYILGSINIFQPINWIFVKSSIVFPIDYVLMALLVLFLFSSSVTGIAAIGLRFLWVKLFEIRKGHTSPQALLMATVMLTLIILAINYSIAMLIAPQYAIYGAQTFCANPTKFPGDQPDCSNHPELIKTCSELSSGEGAEKVCTPSVVSTFLNRVTVNFPFFGALAFWAQFVFLAIFLIVFVTALFRTPKLDLSEIDEDAEADEEEGLLASTGRRFGATWQDIRGKTQNTSGGAAGRGIRGDDDHNDD
What is the function of this protein?
Probable lysosomal cobalamin transporter.  Required to export cobalamin from lysosomes allowing its conversion to cofactors (By similarity).
What are the official names of this protein?
Probable lysosomal cobalamin transporter.
What is the protein family that this protein belongs to?
Belongs to the LIMR family. LMBRD1 subfamily.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.
Protein: ASSY_PSEU2
Sequence: MADVNKVVLAYSGGLDTSVILKWLQDTYNCEVVTFTADLGQGEEVEPARAKAQAMGVKEIYIDDLREEFVRDFVFPMFRANTVYEGEYLLGTSIARPLIAKRLIEIANETGADAISHGATGKGNDQVRFELGAYALKPGVKVIAPWREWDLLSREKLMDYAEKHNIPIERHGKKKSPYSMDANLLHISYEGGVLEDTWTEHEEDMWRWTKSPEDAPNVATYLELTYRNGDIVALDGVEMTPATVLATLNRIGGENGIGRLDIVENRYVGMKSRGCYETPGGTIMLRAHRAIESITLDREVAHLKDELMAKYASLIYTGYWWSPERLMLQQMIDASQVHVNGVVRLKLYKGNVIVTGRKSDDSLFDANIATFEDDAGAYDQADAAGFIKLNALRMRIAANKGRKLF
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IQGA1_MOUSE
Sequence: MSAAEEVDGLGVVRPHYGSVLDNERLTAEEMDERRRQNVAYEYLCHLEEAKRWMEACLGEDLPPTTELEEGLRNGVYLAKLGNFFSPKVVSLKKIYDREQTRYKATGLHFRHTDNVIQWLNAMDEIGLPKIFYPETTDIYDRKNMPRCIYCIHALSLYLFKLGLAPQIQDLYGKVDFTEEEINNMKIELEKYGIQMPAFSKIGGILANELSVDEAALHAAVIAINEAIDRRVAADTFTALKNPNAMLVNLEEGLAPTYQDVLYQAKQDKMTNAKNRTENSDRERDVYEELLTQAEIQGNVNKVNTSSALANISLALEQGCAVTLLKALQSLALGLRGLQTQNSDWYMKQLQSDLQQKRQSGQTDPLQKEEVQAGVDAANSAAQQYQRRLAAVAAINAAIQKGIAEKTVLELMNPEAQLPQVYPFAADLYQKELATLQQQSPEHSLTHPELTVAVEMLSSVALINRALESGDMTTVWKQLSSSVTGLTNIEEENCQRYLDELMKLKAQAHAENNAFITWNDIQACVDHVNLVVHEEHERILAIGLINEALDEGDAQKTLQALQIPAAKLEGVLAEVAQHYQDTLIRAKREKAQETQDESAVLWLDEIQGGIWQSNKDTQEAQRFALGISAINEAVDSGDVGRTLSALRSPDVGLYGVIPECGETYQSDLAEAKKKRLAAGDNNSKWVKHWVKGGYHYYHNLETQAGGWAEPPDFVQNSVQLSREEIQSSISGVTAAYNREQLWLANEGLITKLQACCRGYLVRQEFRSRMNFLKKQIPAITCIQSQWRGYKQKKAYQDRLAYLHSHKDEVVKIQSLARMHQARKRYRDRLQYFRDHINDIIKIQAFIRANKARDDYKTLINAEDPPMIVVRKFVHLLDQSDQDFQEELDLMKMREEVITLIRSNQQLENDLNLMDIKIGLLVKNKITLQDVVSHSKKLTKKNKEQLSDMMMINKQKGGLKALSKEKREKLEAYQHLFYLLQTNPTYLAKLIFQMPQNKSTKFMDSVIFTLYNYASNQREEYLLLRLFQTALQEEIKSKVDQIQEIVTGNPTVIKMVVSFNRGARGQNALRQILAPVVKEIMDDKSLNIKTDPVDIYKSWVNQMESQTGEASKLPYDVTPEQALSHEEVKTRLDNSIRNMRAVTDKFLSAIVSSVDKIPYGMRFIAKVLKDSLHEKFPDAGEDELLKIIGNLLYYRYMNPAIVAPDAFDIIDLSAGGQLTTDQRRNLGSIAKMLQHAASNKMFLGDNAHLSIINEYLSQSYQKFRRFFQVACDVPELQDKFNVDEYSDLVTLTKPVIYISIGEIINTHTLLLDHQDAIAPEHNDPIHELLDDLGEVPTIESLIGESCGNSNDPNKEALAKTEVSLTLTNKFDVPGDENAEMDARTILLNTKRLIVDVIRFQPGETLTEILETPATNEQEAEHQRAMQRRAIRDAKTPDKMKKSKPMKEDNNLSLQEKKEKIQTGLKKLTELGTVDPKNRYQELINDIAKDIRNQRRYRQRRKAELVKLQQTYSALNSKATFYGEQVDYYKSYIKTCLDNLASKGKVSKKPREMKGKKSKKISLKYTAARLHEKGVLLEIEDLQANQFKNVIFEIGPTEEVGDFEVKAKFMGVQMETFMLHYQDLLQLQYEGVAVMKLFDRAKVNVNLLIFLLNKKFYGK
What is the function of this protein?
Plays a crucial role in regulating the dynamics and assembly of the actin cytoskeleton.  Binds to activated CDC42 but does not stimulate its GTPase activity (PubMed:16968698).  It associates with calmodulin.  Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane.  May promote neurite outgrowth.  May play a possible role in cell cycle regulation by contributing to cell cycle progression after DNA replication arrest.
What are the official names of this protein?
Ras GTPase-activating-like protein IQGAP1.
What are the subcellular locations of this protein?
Cell membrane. Nucleus. Cytoplasm. Note=Subcellular distribution is regulated by the cell cycle, nuclear levels increase at G1/S phase (PubMed:20883816).
Protein: CPFC_ALKCK
Sequence: MEKKKIGLLVMAYGTPRKKEEIEPYYTHIRHGRKPSEEALADLQERYEAIGGTSPLARITDEQANGLAAVLNEQQEDIVFVPYLGLKHIDPFIEDAVQKMKNDGIETAVSIVLAPHFSTFSVQSYNKRAQEEADRIGGPTIYTIESWYKEPGFLQFWKEQIENEMKKADSIDDLCVIFSAHSLPEKIIQANDPYPEQLRETADLLADMANVPNYEIGWQSEGNTPEPWLGPDVQDLTRELYAKKGYKTFMYCPVGFVAEHLEVLYDNDYECKLVTDELGVRYLRPPMPNADTRFLKALADVVTKRLAAVVTK
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_GLUDA
Sequence: MATKLDYYAVLEVTRDANGDELKKAYRRLAMQYHPDRNPGDASAEARFKEINEAYDILKDEQKRAAYDRFGHAAFEGGGPGAGGFDFGGGLGDIFEQMFGDMMGGRRGGRRSGSDIQIQVSISFTEAFTGVKKPITVPTRVTCESCEGTGSADRDQGAETCPTCHGAGKVRAQQGFFLVERACPTCHGAGKVVRNPCAACHGAGTVERERTLEVAIPAGVEDGTRIRLSGEGEAGGKGAAPGDLYIHVAVEPHPIFQRDGANIYCRVPLRMSLAALGTEIEVPVVDGSRTKVKVPAGTQTGENFRLRGKGFSVLRSSARGDMYIQVSVETPRHLTKRQRELLEEFEAEAGDHERANPESTGFFSKVRDFFEGKL
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1266_METJA
Sequence: MPYYWGAILIGGVFLAGCTQNQETTTTQSGSKENVIKVGLLVDLSGGLATYGNNEKHICEIAEEKINKYFEEKGMPYKVKLYVEDTRADPNICLQKVQALHAQGITFFLGPMASGEVKNIKGFINSNKIVIISPSSTAPPQMLGFRTPEEKKYVFRFVPTDNFQGNAIGDVAKQLGLKNVIVIYRKDAWGDGLERATVEKLKANGINIIDEIPYDPNIGDWSPIIQTTTNKIAGKGNDTGVIFIGYEEVATLLSQIDDNSPLLKHVWIGCDGTANSKKVLEEAKNKAVKVKLYSTMFQSETDEAEKIKEEFKKRGYGEPDQYALNVYDAFWVGAISYAEMLNKTGGKYDADLLSKLIKENTVKYSEGQFGVKSVTGYIKLNEWNDRASGNYGIFAVTEDGWKLVGVWDSTTGKINWK
What are the official names of this protein?
Uncharacterized protein MJ1266.