PharMolix/UniProtQA huggingface dataset:
Protein: YK1D_SCHPO
Sequence: MSSSKIKELREGLMSSSKWSMAPGMMMQQNQPRPATTTPPISRGNEDADEGLNTARSFSSFQDLKGMSGDAKEQESATLVHLTKGRAHPRSRRPPRQISIDSAKKEETKNTGSTKAADTKSSVEATISPLKDTKSPSNASVFPIKPTESKTSTTKDSETAKEEDDASSSTTKAVEATTSKASSAHTDTLATSASNSDRGASTPEMVVKAEKREGSTSPIPYSSLSIAERIKQAQNTPFLESKVLPQNNETSDEENVDVKPAAGTVKNVMQAFLQPATPAKDTASKEPSKSSQQPVRTKPRIAQSPFLAQDAKENGGNVEVSSPLSFSASKSPAAVDSSTKTPTEQVNVVSKQAPTTSSTSVISPDPLQTAAPSANVNEVIASLESKVVTRRTGSGNNYRVGLRNVSGSERTKSLSKESPVEPEKPALPDATSSSTPTTENKESWTNQGIKSSQQRSANASPATSPSNQASIHASFTKESSTHSSPSFTLESLFSGAPRVVELTRFSQPSPACSRALLARWKEEYRTSIH
What are the official names of this protein?
Uncharacterized protein PB1A10.13.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at the cell tip and barrier septum.
Protein: PAPO2_XENLA
Sequence: MLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRAVMVEEFKQGLAITDEILLVKAEWSKLFDAPNFFQKYKHYILLLASAPTEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQSFPSPSENSEKEEFRTMWVIGLVFKKMENSENLSVDLTYDIQSFTDTVYRQAINSKMFETEIKIAAMHVKRKQLHQLLPSHVLPKKKKHSVEGVKLVSLNDSSIDLSVDSDNSMSVPSPTNATRTSPLNSTGLSQGNSPATPVSLSVTNTQATDVMVPQNNSTENSGGSLNESIPETATHPAFSSTPRPLVTRVVSSMPLVNQVQKPVTNTVTKMPSPVAGVKRTSSPTNEESPKKTKTEEDENDSSNSTEVDEQNKLEPEELKEVHSEEKSSSPVPGALPSSQRSSSTDLSDISVLPATPIPVIKNSIKLRLNR
What is the function of this protein?
Polymerase that creates the 3'-poly(A) tail of mRNA's.  May acquire specificity through interaction with a cleavage and polyadenylation factor (CPSF).
What are the official names of this protein?
Poly(A) polymerase alpha-B, PAP-alpha-B, Polynucleotide adenylyltransferase alpha-B.
What is the protein family that this protein belongs to?
Belongs to the poly(A) polymerase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COFH2_METMP
Sequence: MDLMSFKEREISKKDCVELFEDTENFFDILKLADSIRKDIVGDTVTFVKNTNIETTNVCTMGCKFCAFSVSKNSPEAFKLDADEIAKKAVIAKKSGLTEVTIHGGIHPDVDTHFQVETINKVNSATSKLGGIYTHAYSPQEILNGAENAGLSIKEALKMLNEAGLRTIPGTAAEILDDEVRSDICPLKMSTKKWIDIMKTAHKTGIKTTSTIIYGHVEEYKHIVDHLSILKELQEETGGITEFIPMSFLHENTPLYKSGRVTDGASGLYELKLYAIARILFKESIKNIQAPRVKIGTKLSQLILKSGANDLGGTLVEDKVSKAAGSIYEDASVDLMKNAITSIGRIPKERTTLYEIIE
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
What are the official names of this protein?
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase 2, FO synthase subunit 2 2.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofH family.
Protein: CH10_HAHCH
Sequence: MKIRPLHERVVVRRKEEETKTAGGIVLPGNAAEKPSQGEVLAVGEGRILDNGDVRPLAVKVGDKVVFGQYAGSTVKIDGEELLIMSESDIFGVIEG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T11L2_BOVIN
Sequence: MPFNGEKQCVSEDQPSDSDSSRFSESMASLSDYECSRQSFTSDSSSKSSSPASTSPPRVVTFDEVMAAARNLSNMTLAHEIAVNENFQLKQDALPESSLAGRVRHIVHQAFWDVLESELNAEPPEYEHAIKLFEEIREILLSFLTPGGNRLRNQICEVLDTDLIRQQAEHSAVDIQGLANYVISTMGKLCAPVRDDDIRELKATSNIVEVLRQIFHVLDLMKMDMVNFTIRSLRPHLQRQLVDYERTKFQEILEETPSALNQTTEWIKESVHEELLSLSEATLTPGAENNSKPSLSPTLVLNNSYLKLLQWDYQKKELPETLMTDGARLQELTEKLNQLKMIACLALITNNMVGALTEGLPELAVRLKRISAVLLEGMNKETFNLKEVLNSIGIQICVEVNKTLMERGLPTLNAEVQDNLVGQFSSIEEEDNPIWSLIDKRIQLYMKSLLCLPSPPRCMPPVPGGLAVVQQELESLGLQYANIVNLNKQVYGPFYANILRKLLFGEEATGKAEASSSTN
What are the official names of this protein?
T-complex protein 11-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the TCP11 family.
Protein: NHAA_SHEPC
Sequence: MEKAIRNFLSQESAGGILLLVAVVFAMLMANSPLSGLYQGFLGTDVQVRVGALDIHKPLLLWINDGLMALFFLLIGLEVKRELLEGALSSVAQASLPSFAAIGGMLVPAGIYLLFNYGDPVTQAGWAIPAATDIAFALGIMALLGNRVPVALKVFLLALAIIDDLGVIVIIALFYSSDLSTISLAIASVAILGLVGLNRKGITALTPYGILGLILWVAVLKSGVHATLAGVIIAFCIPLRAKDGSSPSEHLEHSLHPWSNFLILPVFAFANAGVALGNMSLDTLLSPVPIGIALGLILGKPIGVMLFSFIAVKLKLARLPDNVGWMQIAPVAAMCGIGFTMSMFIASLAFEQADPMYGDLARLGTLIGSFIAALVGYFWLSKVLPKKGVLL
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISPT_RHOBA
Sequence: MTSVPLLSMNLPRHVAIIMDGNGRWAQARDLPRIEGHRRGVTTVRTVTEMASELKLDALTLYCLSSENWKRPQAELDFLMHLLQQYLVEERRTIRDQNMRLRFIGRRDRLSDEVLKEIAKTQAVSENNTGTELVLAVDYGGRDELTRMTRQLAQQVRDGERSIDEITESLVDESLDTAGLPDVDLMIRTGGDIRISNYLLWQISYAELYFTPKCWPEFERDDFQAALDEFAGRQRRFGGLNVGA
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: RL35_CHLP8
Sequence: MPKMKSHRGACKRFKATGSGKVKRERMNGSHNLEHKNRKRTRRLHQSTLVDSTKEKQIKRMILA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RPOC_CHLSY
Sequence: MLEINDFNAIRISLASPEDIRSWSHGEVTKPETINYRTLKPERDGLFCERIFGPTKDWECFCGKYKRVRYKGVVCDKCGVEVTRSKVRRERMGHINLASPVSHIWFVKGTPSRLGLLLDISPRNLERVLYFASYIIVEVKEDMLQVAREMIQEEYAARRQKIQKQAEEKRIELSTQLTQDLGGMETAQRSTQRQIEEEYRRLRDEIASEAEQLRERLEELSGTLADEDILFRGVTVVEEGEPINENTLDQLDELVEQELEVLEERRRRDLADAELLTDAERERKAYEATQEQERLQERLQRELDHLMREEKEKLEQLDTLKVGRIITETEYRQLRDIAPGVFRADMGAGAVRELIEKTVNLDKLAEELQAEIQSSQGQRRKKATKRLRVVEAFRKSGNRPEWMILTVLPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLIELNAPEIIVRNEKRMLQEAVDALIDNGRRGRAVSGKGKHRLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPNLQLHQCGLPKKMALELFKPFVMRRLVERGVAHNIKNAKRAVERVRPEVWDALEEVIKDYLVLLNRAPSLHRLSIQAFEAKLIEGSAIQLHPLVCAAFNADFDGDQMAVHVPLSRKAQEEARTRMLSKYNLLSPAHGEPIITPSQDIVLGCYYLTMVRDGAKGSGKRFSSIDEAMLAYEKHLLDIQAPIWIRMTGTLSGKSDRPVRELPLAADGTPRMLIETTIGRILLNNELQPPLRFRNRLIDKKGLKEIIADCYQYYTNLRNLSEDQLNEVRASHGNKHVQELARIYGSEMTAQQADRIKALGFRYATLGGMTIGIEDIEVPAKKYDIVREAEQLVADVEKQFRRGLITEEERYQEVVRIWQEATKQTIQAVKENLNPFGPVAMMSTSGARGNINQISQMAGMRGLMSDPTGRIIELPIKANFREGLSVLDYFVSTHGGRKGLADTALRTADAGYLTRRLVDVAQDVIITIEDCGTEEGLWLHGADDDELMEKLQVRMLGRILAAPIYHKETGELIADRNTEIDEELATAILASGQESVFVRSPLSCQAEHGLCRLCYGRNLATGKLVEIGEAVGIIAAQSIGEPGTQLTLRTFHTGGVASADDITQGLPRVQEIFEARVPKGKALLAEIDGVVQIVRDEEGVRTIRIVSTDVYTDEYPLGRGFSPTINHESEVYEGQVIAEGPGGAQIVTRLTGKAFIQGDRIIVSQEDHQERELVVPHNARIRVENGERVMAGQQLTDGSANPQELLELQGREAVQRYLVNEAQKVYRSQGVNINDKHIEVIVRQMLRRVRIEDPGDTGLLPGELIDSAEFRRLNNDIVSQGGDPATAATMLLGITKASLNTDSFLAAASFQETTRVLTDAAIQGKVDYLRGLKENVVIGKLIPAGTGIEKRIERPHEDLIGEMARMLEESQQAEEAPAETRRATPLPTPNGNKAPESDNDALLRARLEELLSGDGDNDQSDAEEEDNDLPAF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RL20_HALH5
Sequence: MPRVKGGYVARRRRKKVLKLAKGYFGSKHTLFKSAQGQVMKSLQYAYRDRRQKKRDFRKLWITRINAAARLNGLSYSRLMHGLKLAGINVNRKMLADLAINDEKAFAQLAEKAKASLNN
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: P2RY8_HUMAN
Sequence: MQVPNSTGPDNATLQMLRNPAIAVALPVVYSLVAAVSIPGNLFSLWVLCRRMGPRSPSVIFMINLSVTDLMLASVLPFQIYYHCNRHHWVFGVLLCNVVTVAFYANMYSSILTMTCISVERFLGVLYPLSSKRWRRRRYAVAACAGTWLLLLTALSPLARTDLTYPVHALGIITCFDVLKWTMLPSVAMWAVFLFTIFILLFLIPFVITVACYTATILKLLRTEEAHGREQRRRAVGLAAVVLLAFVTCFAPNNFVLLAHIVSRLFYGKSYYHVYKLTLCLSCLNNCLDPFVYYFASREFQLRLREYLGCRRVPRDTLDTRRESLFSARTTSVRSEAGAHPEGMEGATRPGLQRQESVF
What is the function of this protein?
Probable receptor for purines coupled to G-proteins.
What are the official names of this protein?
P2Y purinoceptor 8, P2Y8.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RECF_ECO45
Sequence: MSLTRLLIRDFRNIETADLALSPGFNFLVGANGSGKTSVLEAIYTLGHGRAFRSLQIGRVIRHEQEAFVLHGRLQGEERETAIGLTKDKQGDSKVRIDGTDGHKVAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEPGFFTAWSNLKRLLKQRNAALRQVTRYEQLRPWDKELIPLAEQISTWRAEYSAGIAADMADTCKQFLPEFSLTFSFQRGWEKETEYAEVLERNFERDRQLTYTAHGPHKADLRIRADGAPVEDTLSRGQLKLLMCALRLAQGEFLTRESGRRCLYLIDDFASELDDERRGLLASRLKATQSQVFVSAISAEHVIDMSDENSKMFTVEKGKITD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECT2_ARATH
Sequence: MATVAPPADQATDLLQKLSLDSPAKASEIPEPNKKTAVYQYGGVDVHGQVPSYDRSLTPMLPSDAADPSVCYVPNPYNPYQYYNVYGSGQEWTDYPAYTNPEGVDMNSGIYGENGTVVYPQGYGYAAYPYSPATSPAPQLGGEGQLYGAQQYQYPNYFPNSGPYASSVATPTQPDLSANKPAGVKTLPADSNNVASAAGITKGSNGSAPVKPTNQATLNTSSNLYGMGAPGGGLAAGYQDPRYAYEGYYAPVPWHDGSKYSDVQRPVSGSGVASSYSKSSTVPSSRNQNYRSNSHYTSVHQPSSVTGYGTAQGYYNRMYQNKLYGQYGSTGRSALGYGSSGYDSRTNGRGWAATDNKYRSWGRGNSYYYGNENNVDGLNELNRGPRAKGTKNQKGNLDDSLEVKEQTGESNVTEVGEADNTCVVPDREQYNKEDFPVDYANAMFFIIKSYSEDDVHKSIKYNVWASTPNGNKKLAAAYQEAQQKAGGCPIFLFFSVNASGQFVGLAEMTGPVDFNTNVEYWQQDKWTGSFPLKWHIVKDVPNSLLKHITLENNENKPVTNSRDTQEVKLEQGLKIVKIFKEHSSKTCILDDFSFYEVRQKTILEKKAKQTQKQVSEEKVTDEKKESATAESASKESPAAVQTSSDVKVAENGSVAKPVTGDVVANGC
What is the function of this protein?
Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability (Probable) (PubMed:29716990, PubMed:29618631).  M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing (Probable) (PubMed:29716990, PubMed:29618631).  Binds preferentially in the 3'UTRs of target genes (PubMed:29716990).  May play dual roles in regulating 3'UTR processing in the nucleus and facilitating mRNA stability in the cytoplasm (PubMed:29716990).  Required for the correct timing of leaf formation and normal leaf morphology (PubMed:29643069).  Functions redundantly with ECT3 (PubMed:29643069).  Required for proper trichome branching and morphology (PubMed:29643069, PubMed:29716990, PubMed:29618631).  Controls trichome morphology by binding transcripts related to trichome morphogenesis and affecting their stability (PubMed:29716990, PubMed:29618631).
What are the official names of this protein?
YTH domain-containing protein ECT2, Protein EVOLUTIONARILY CONSERVED C-TERMINAL REGION 2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes to cytoplasmic foci upon drought stress (PubMed:29643069). Relocates to cytoplasmic stress granules upon heat stress (PubMed:29618631).
Protein: CCA_BACVZ
Sequence: MEQEFVKALPILHHLMKAGHQAYFVGGAVRDSYMKRKIGDVDIATSASPNEVERLFKRTVDVGKEHGTVIVLWEDETYEVTTFRAESEYKDYRRPEAVRFITSLSEDLKRRDLTINAMAMSAEGELLDYFGGAHDIGQKLIRTVGNPEDRFREDALRMMRAVRFMSQLGFLLEKETREAVIKDRELLAHVSVERKTVEFEKLLQGASSQEAIQTMVQTGLIQELPGLSGYEQQMLEASGFPFSSLDAREERWAALLLFLGLCPKSAEAFLKQWKLPGKVIKKAMQIISVYPAQLEAEAMYRAGEALFSAVKIGMLKKHKTIDEQKLKEVQSLYEQLPIKSLRDLDISGADLMELRNRRAGKWVAEELRRIEEAVLAGKLPNRKHDIKEWLASWDQH
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
Protein: EFTS_AERHH
Sequence: MANISAALVKELRERTAAGMMDCKKALEEAAGDIELAIENMRKSGQAKAAKKAGRIAAEGVIFARTEGNVAVMIELNCETDFVSKDAGFLAMGQKIVEIAATQKIADVDALKAADFGNGESVELTITNLIAKIGENMNLRRVMLVEGDNLGTYVHGSRIGVITKLAGGSDELAKDLAMHVAANSPQFVKPEDVSAEVVAKEREIQIDIAINSGKPKEIAEKMVEGRMKKFTGEVSLTGQPFVKDPSMTVAELLKKEGADVVSFTRFEVGEGIEKQETDFAAEVAAQIAAAQKA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_STRP8
Sequence: MTEISILNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKITAQELREINPIGIVLSGGPNSVYADNAFGIDPEIFELGIPILGICYGMQLITHKLGGKVVPAGQAGNREYGQSTLHLRETSKLFSGTPQEQLVLMSHGDAVTEIPEGFHLVGDSNDCPYAAIENTEKNLYGIQFHPEVRHSVYGNDILKNFAISICGARGDWSMDNFIDMEIAKIRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKDEGDQVMGMLGGKFGLNIIRVDASKRFLDLLADVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGIALGMPEEIVWRQPFPGPGLAIRVMGAITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWDVLKKISTRIVNEVDHVNRIVYDITSKPPATVEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: FTSH1_SYMTH
Sequence: MRWWAGAALLLAALLFGRPAAAMEAQPVAYSEFIQDVQARRVAYARITGQRLEAAYRDGTVRVVTLPPGEARLPLVLMQYGARVEFVRPADPIAFRTLLRFIPPLLILGAILWFTRRTAGGSGGLLTMEQSPARLYRVGEASVTLQDVAGLDEVKAELQEVIDFLREPERYRAMGARIPRGILLSGPPGTGKTLLARALAGEAGVPFFSASGSDFVELFAGTGAARVRALFDRARKAAPCIVFIDEIDALARRRGVGAGGGTEEREQTINQLLVEMDGFDSGEGVIVVAATNRPDVLDPAVLRPGRFDRHLTVDPPDRKGREQILAVHAREKRLSQAVALAEVARLTPGFTGADLANLLNEAALLAVRAGEREIGWPQVAMALERVTSGGPPRRVRAAAADRVRAAYHEAGHALAGLALRGSDRLVRVTILPHGRGLGHTLFRDQDEERYLHTRRDAFDRLTELLAGRAAEALVLGEVSAGAADDLERATGLAREMVTRWGMDADIGPLRLEHAVEGEESLRRADGAMRALVAAAERAARALLEARRSGLERLAAALLERERLEGPEVEALLELTPGEKPYIIVANSRGDEGNQ
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH 1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: FOCB_ECOLI
Sequence: MRNKLSFDLQLSARKAAIAERIAAHKIARSKVSVFLMAMSAGVFMAIGFTFYLSVIADAPSSQALTHLVGGLCFTLGFILLAVCGTSLFTSSVMTVMAKSRGVISWRTWLINALLVACGNLAGIACFSLLIWFSGLVMSENAMWGVAVLHCAEGKMHHTFTESVSLGIMCNLMVCLALWMSYCGRSLCDKIVAMILPITLFVASGFEHCIANLFVIPFAIAIRHFAPPPFWQLAHSSADNFPALTVSHFITANLLPVMLGNIIGGAVLVSMCYRAIYLRQEP
What is the function of this protein?
Involved in the bidirectional transport of formate during mixed-acid fermentation.
What are the official names of this protein?
Formate channel FocB, Formate transporter FocB.
What is the protein family that this protein belongs to?
Belongs to the FNT transporter (TC 2.A.44) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YEJL_ECO27
Sequence: MPQISRYSDEQVEQLLAELLNILEKHKAPTDLSLMVLGNMVTNLINTSIAPAQRQAIANSFARALQSSINEDKAH
What are the official names of this protein?
UPF0352 protein YejL.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: LEUD_PELUB
Sequence: MQKFNSLTSIPAYLPIVNIDTDMIIPKQFLKTIKRTGLGKNLFFEMRYDDNGNEIKDFILNQKPHNQSKILIAGKNFGCGSSREHAPWALLDFGITCVISSSYADIFYSNCFKNGILPITLPEEKIKELSEYSKRKEEISIDLNEEKIIFGNSEIKFDIDPFKKKCLLEGLDDIALSLAKKEKIITFEENLKNNKPWIFNDKN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: PEX5_KLULA
Sequence: MSADCSVGSNPLAQLNKHAQQNPALRQVGYQNPASNVAQNFKTHVNEVSNANRFQMDQFMNRSPGFSDGQLGMAPVPSAILSHGPRFGLKKQDSGSSNMSAGDTAQHSRSWGNEFNSRSPQQGLASRVNNVERISNTNSMSSYRPGMSRIGRPMMHTGISSLHNYSHMSQQTPQMSSDDGVLADKQWNEQFEALEKAVAENLTMEDNKEETKEEIVVEDGYQADFQEVWDKLQAETADNNLETSDSQWEKDYARYMTGKATHIPPYRFDNDNQYMHNPNAYEIGCILMENGAKLSEAALAFEAAVQEDPAHVDAWLKLGLVQTQNEKEMNGISALEQCLSLDPTNQQALMTISISYINEGYDLTAFSMLNRWLDSKYPELTRSPTIDEANIDRFNLSKQVITKYLQVANALPQVDPEVQLGLGTLFYANEEFGKTIDCFRTALEVNPNDELMWNRLGASLANSNRSEEAIQAYHKALALKPSFVRARYNLAISSMNIGCYKEAAESLLSALSMHEVENVPITGSVVQSNNILETLKRSFVAMDRRDLLEKVMPGMDLQQFRNEFNF
What is the function of this protein?
Receptor that mediates peroxisomal import of proteins containing a C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type).  Binds to cargo proteins containing a PTS1 peroxisomal targeting signal in the cytosol, and translocates them into the peroxisome matrix by passing through the PEX13-PEX14 docking complex along with cargo proteins.  PEX5 receptor is then retrotranslocated into the cytosol, leading to release of bound cargo in the peroxisome matrix, and reset for a subsequent peroxisome import cycle.
What are the official names of this protein?
Peroxisomal targeting signal receptor, PTS1 receptor, PTS1R, Peroxin-5.
What is the protein family that this protein belongs to?
Belongs to the peroxisomal targeting signal receptor family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome membrane; Peripheral membrane protein. Note=Its distribution appears to be dynamic. It is probably a cycling receptor found mainly in the cytoplasm and as well associated to the peroxisomal membrane (By similarity).
Protein: SYH_THEAB
Sequence: MYKRIKGTEDIFGDDIKYWYYIENVVKETVRLYGYSEIRTPIFEATELFIRSVGEETDIVQKEMYTFEDKGQRSITLRPEGTAPTIRAFIENSMMATGLPKRLFYIGPMFRYERPQKGRQRQFHQFGVELIGSPSPLADAEAIIVADRVLKNLGLLNYTIKINSIGCDKCRANYKNALKEYYSDKLDYVCDDCKRRYNTNVLRLLDCKVDVEYIKDAPKITDYLCDDCKHHYEETKRLLDNLKIKYVEDPLLVRGLDYYNGVVFEIHHGDLGAQSAVGGGGRYDKLIKELGGSQTPSLGFAMGIERLIIALKNEKIPVEEIKNNEIFVAHLGEQARIEALKIAEDLRDNGISVVFSTMERGLSAQLKHAARLKCKLCVIVGENELERNIVILRNMETGEQIEIERDYVVGTAKEWIEG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDI_MYCTU
Sequence: MDIAGRSLVYFSSVSENTHRFVQKLGIPATRIPLHGRIEVDEPYVLILPTYGGGRANPGLDAGGYVPKQVIAFLNNDHNRAQLRGVIAAGNTNFGAEFCYAGDVVSRKCSVPYLYRFELMGTEDDVAAVRTGLAEFWKEQTCHQPSLQSL
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: Y069_ARCFU
Sequence: MSEFKLGDIFGCEAVKNFGAALRKALRIGDDYASLVELEYVETKEQFEEVIKKFLRRYETIARRGYKGKELSRLSEKDLEELMSLVDKYDVKPIRAALISYALVKSEREDEATLKSEEVV
What are the official names of this protein?
Uncharacterized protein AF_0069.
Protein: AROE_STRP1
Sequence: MSERLSGHTLLVSLLATPIRHSLSPKMHNEAYAKLGLDYAYLAFEVGTEQLADAVQGIRALGIRGSNVSMPNKEAILPLLDDLSPAAELVGAVNTVVNKDGKGHLVGHITDGIGALRALADEGVSVKNKIITLAGVGGAGKAIAVQLAFDGAKEVRLFNRQATRLSSVQKLVTKLNQLTRTKVTLQDLEDQTAFKEAIRESHLFIDATSVGMKPLENLSLITDPELIRPDLVVFDIVYSPAETKLLAFARQHGAQKVINGLGMVLYQGAEAFKLITGQDMPVDAIKPLLGDE
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: RL3_CARRU
Sequence: MIFINKGTKHFFYKKKLYIFNVIKFSKFNKFYLNFIINKILLICYSKGKGFQGVVKRWNFKTKDKSHGNSLSYRTLGSTGQCQDPGRVFKKKKMPGRMGNKKFSLFVNIFFRKKNYFFLKKILPGVKNDILLGKIL
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: ACKA_DESPS
Sequence: MKILIINSGSSSIKFQLIDMSDESVLASGLVERIGETDTTEKNINCTFHPGTDKKHKIEICQTVADHRQGMLAAIELLGDKEQAVMSDLSEIDAVGHRIVHGGETMYQPVVVDEKVIAEITAAIPLAPLHNPGHLDGIKVAQELFTEVPHVTVFDTAFFQTIPPHAHIYALPYELYTKHRIRRYGAHGTSHKFVTNECAKLLEKPVEECNLITVHLGNGSSMSAVEGGKAIDTSMGVTPLEGLVMGTRSGDIDPAIMAFLNRNLGMSIEEIDHMLNKESGLKGICGMNDMRDIHAAADAGNELAELAVGIQTYRIRKYIGSYMAALGQVDAIVFTAGIGENDDIVRAKSLEKLENLGVILDKKLNAQRSKEPFCISTPESKIQVWVIPTNEELAIARETKAVVNA
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPRX_RAT
Sequence: MESLFPAPYWEVLYGSHFQGNLSLLNETVPHHLLLNASHSAFLPLGLKVTIVGLYLAVCIGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPAPQDYWGPVFAICIFLFSFIIPVLIISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLVQGLGVQPGSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASSLHREMQVSDRVRSIAKDVGLGCKTSETVPRPA
What is the function of this protein?
G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors.  Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity.  Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases.  Plays a role in modulating nociception and the perception of pain.  Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
What are the official names of this protein?
Nociceptin receptor, Kappa-type 3 opioid receptor, KOR-3, Orphanin FQ receptor, ROR-C, XOR1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle. Note=Ligand binding leads to receptor internalization into cytoplasmic vesicles, decreasing the amount of available receptor at the cell surface (By similarity). Internalization requires phosphorylation at Ser-360. Can recycle to the cell membrane.