PharMolix/UniProtQA huggingface dataset:
Protein: METQ_SALTI
Sequence: MAFKFKTFAAVGALIGSLALAGCGQDEKDPNHIKVGVIVGAEQQVAEVAQKVAKEKYGLDVELVTFNDYVLPNEALSKGDIDANAFQHKPYLDQQIKDRGYKLVSVGKTFVYPIAGYSKKIKSLDELKDGSQVAVPNDPTNLGRSLLLLQKVGLIKLKDGVSLLPTSLDIVENPKNLKIVELEAPQLPRSLDDAQIALAVINTTYASQIGLTPAKDGIFVEDKDSPYVNLIVTREDNKDAENVKKFVQAYQSDEVYEAANKVFNGGAVKGW
What is the function of this protein?
This protein is a component of a D-methionine permease, a binding protein-dependent, ATP-driven transport system.
What are the official names of this protein?
D-methionine-binding lipoprotein MetQ.
What is the protein family that this protein belongs to?
Belongs to the NlpA lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: NU2C_PROM3
Sequence: MPEMGVFLLATQAMAAPGELLNLALNAGAIAPEGAVLVAMLATLLVDLAGEQAAARWVPPICYAGLGTALVLLAQQWNAPLEPSFLGAFLADNLAIAFRAVVALSTLLSLLISWRYAEQSGTPIGEYAAILLAATLGAMLLCGSTDLVSVFVSLETLSVASYLLAGYMKRDARSSEAALKYLLVGSAAAAVFLYGASLLYGLSGTTSLQAIGIALLTSPTPLAALSLVFVLATVAFKIAAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAGFALALRLLVGCFGAFDNQWKLLFTVLAVLSMTLGNVVALAQTSMKRMLAYSSIGQAGFVMIGLVCGTEDGFAAMVLYMAAYLFMNLGAFACIILFSIRTGSDRISDYAGLYQKDPLITLGLSLCLLSLGGIPPMLGFFGKIYLFFAGWADHQYLLVVVGLVTSVVSIYYYISVIKMMVVKEPKEASDVVKSYPSIQWSTIGMPPLRIALVGCVVVTAVGGILSNPLFQWANNAVAGTPLLQEAIALGSQRSIG
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2, NAD(P)H dehydrogenase subunit 2, NADH-plastoquinone oxidoreductase subunit 2, NDH-1, subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: CYSG_XYLFT
Sequence: MTANVLFPLFANLHDRAVLVVGGGKVAERKTEALLKVGALPIIGAPSLTASLQRWAETGRITWRQGTFENSWLQEDIWLVIAATDQPEVNHAAARAAHAQRLFVNVVDDIALSNVQVPAVVERGPLRIAISSGGGAPMVARYLRQQLESLIDDSWGRLTTLFAQRRDTIRARYPNIEARRRFFETQLAGPLQRLLRKQRHAEAEAVLEAALAKTPPTESGSVTLVGAGAGDAGLLTLNALRALNEADIILYDRLVSDTVLQMARRDAEQIEVGKSATGHSVRQEDIHTLMLQHARAGQRVVRLKGGDPFVFGRGGEELEFLRTHGIPYEVIPGITAALACAAYAGIPLTHRDHAQSLCLITAHCQSSLDTLNWAALAQERQTLAFYMGVAGLPTIQQRLCEAGRTETTPFALIENGARAQQRVLTGTLKTLAHTAQTYAVRPPALLILGEVTALAEHLHWFGTTPLSAPCPPRTHPIS
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: RS15_KINRD
Sequence: MPLDAAVKKSIMAEYATSEGDTGSPEVQVAMLTQRIRDLTEHLKTHQHDHHSRRGLLLLVGQRRNLLKYMAKKDINRYRSIIERLGIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: CARA_LEPBL
Sequence: MKAFLVLDNGMILEGESFGYESESVGEIVFNTSMAGYQEILTDPSYCNQIITLTYPMIGNYGIHPDNMESSKIQASGLIVREYVDLPSNFMSQKTLSKFLKEYQIPAIQGIDTRKLTRYIRTNGSPNGGIFVAREYSPEFLEKVKSFPGITGTDLAKVVTTSTKYIFGTHTGKKYKLAVYDYGVKTNILRLLDAAGFAVTVYPALTPAEEIMKEGTDAFFLSNGPGDPAPLDYAIDATRKIMEKGYPLFGICLGHQIIGLSLGKKTEKMKFGHRGGNQPVKNLSTGQVEITSQNHGFAVIDDGKSSEPVSFLNLNDNTVEGILKSGYPLLTVQYHPESAPGPNDSRYLFQKFYDLVETTKRGK
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: PYRD_RHOPT
Sequence: MIRAFDAVSLPLLRWLDPEDAHRLAIQGLKLWPPVKPRPDDSKLAVRAFGLNFSNPVGIAAGFDKNAEAPDALLRLGFGFVEVGTVTPKPQAGNPRPRLFRLERDEAVINRMGFNNEGAEAVLRRLAARAQYGGIVGVNVGANKDSDDRVADYVKLIETFAPLASYFTVNVSSPNTPGLRNLQQAAALDDLLARVIDARERVRAAAGDTPVLLKIAPDLSLGELDDVVHIARSRRVDGMIVANTTLSRSPTLRERTKMNEQGGLSGRPLFRLSTRMVAETFVRAEGAFPLIGVGGIDSGGAALTKIRAGATLVQLYSALVYKGLGLVESIKADLASTLLRTGRDSLAEIVGADAPMITAEEWPV
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MDH_COXB1
Sequence: MAKHVKVAVTGAAGQIGYALLFRLASGQAFGLDTTVDLHLLEIEPALPALKGVVMELEDCAFPLLRNMVVTSDPRVAFNDVNWALLVGAAPRKAGMERKDLLEKNGSIFAGQGKAINENAASDVRIFVVGNPCNTNCLIAMNNAPDIPKDRFYAMTRLDQNRAIGQLALKAGVDVPSVKNMIIWGNHSSTQYPDFYHATIDGKPATEVIRDKNWLLNDFIPVIQQRGAAVIKARGASSAASAANAALDSVWSLINTTPADDNYSVALCAQGQYGVDEGLIFSFPCRTENGVVSVIEEIEHNEFGQQKLKETLDELREERDAVEALGLI
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: COBIJ_MYCBO
Sequence: MSARGTLWGVGLGPGDPELVTVKAARVIGEADVVAYHSAPHGHSIARGIAEPYLRPGQLEEHLVYPVTTEATNHPGGYAGALEDFYADATERIATHLDAGRNVALLAEGDPLFYSSYMHLHTRLTRRFNAVIVPGVTSVSAASAAVATPLVAGDQVLSVLPGTLPVGELTRRLADADAAVVVKLGRSYHNVREALSASGLLGDAFYVERASTAGQRVLPAADVDETSVPYFSLAMLPGGRRRALLTGTVAVVGLGPGDSDWMTPQSRRELAAATDLIGYRGYLDRVEVRDGQRRHPSDNTDEPARARLACSLADQGRAVAVVSSGDPGVFAMATAVLEEAEQWPGVRVRVIPAMTAAQAVASRVGAPLGHDYAVISLSDRLKPWDVIAARLTAAAAADLVLAIYNPASVTRTWQVGAMRELLLAHRDPGIPVVIGRNVSGPVSGPNEDVRVVKLADLNPAEIDMRCLLIVGSSQTRWYSVDSQDRVFTPRRYPEAGRATATKSSRHSD
What is the function of this protein?
Methylates precorrin-2 at the C-20 position to produce precorrin-3A.
What are the official names of this protein?
Cobalamin biosynthesis protein CobIJ.
What is the protein family that this protein belongs to?
Belongs to the precorrin methyltransferase family.
Protein: DINB_BACSU
Sequence: MSDFAFKLYEYNVWANQQIFNRLKELPKEIYHQEIQSVFPSISHVLSHVYLSDLGWIEVFSGKTLSDALALAEQLKEQTEAKEIEEMEDLFLRLSERYILFLQQKEQLNKPLQIQNPSSGIMKTTVSELLPHVVNHGTYHRGNITAMLRQAGYASAPTDYGLYLFMTKTEKA
What are the official names of this protein?
Protein DinB.
What is the protein family that this protein belongs to?
Belongs to the DinB family.
Protein: DNLJ_MYCTO
Sequence: MSSPDADQTAPEVLRQWQALAEEVREHQFRYYVRDAPIISDAEFDELLRRLEALEEQHPELRTPDSPTQLVGGAGFATDFEPVDHLERMLSLDNAFTADELAAWAGRIHAEVGDAAHYLCELKIDGVALSLVYREGRLTRASTRGDGRTGEDVTLNARTIADVPERLTPGDDYPVPEVLEVRGEVFFRLDDFQALNASLVEEGKAPFANPRNSAAGSLRQKDPAVTARRRLRMICHGLGHVEGFRPATLHQAYLALRAWGLPVSEHTTLATDLAGVRERIDYWGEHRHEVDHEIDGVVVKVDEVALQRRLGSTSRAPRWAIAYKYPPEEAQTKLLDIRVNVGRTGRITPFAFMTPVKVAGSTVGQATLHNASEIKRKGVLIGDTVVIRKAGDVIPEVLGPVVELRDGSEREFIMPTTCPECGSPLAPEKEGDADIRCPNARGCPGQLRERVFHVASRNGLDIEVLGYEAGVALLQAKVIADEGELFALTERDLLRTDLFRTKAGELSANGKRLLVNLDKAKAAPLWRVLVALSIRHVGPTAARALATEFGSLDAIAAASTDQLAAVEGVGPTIAAAVTEWFAVDWHREIVDKWRAAGVRMVDERDESVPRTLAGLTIVVTGSLTGFSRDDAKEAIVARGGKAAGSVSKKTNYVVAGDSPGSKYDKAVELGVPILDEDGFRRLLADGPASRT
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase A, LigA, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: EFTS_STRZT
Sequence: MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREKGMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAEGKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNGGRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNESRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRFMLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEAEVAATMAAALNN
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F16PA_BRUMB
Sequence: MTLVGNFSPLVLVGDSDRVEAETVGAYLDGWAGHDKVRLATANAIKAILSGAGRLVGRIARGYLPGDPGKLVGVNSDQDQQKSIDVGSHNLFVELLIAAGVASILSEEADLPVAGKADGLVAVAIDPLDGSGNVGLGAPLGTIFSIFPADVEEPFLQPGNRQIAAGYVSYGNSVDLGFSVGEGVIFATLDPVSGQFHITRRNVKLPERTSDLAFNASVQRHLSAGMQAYVNDAFLGKDGPRGRNFNMRWLGAAVGDMHRIMQRGGLFFYVNDSRPGYEKGRLRLVYEANPIAFLAREAGGKATDGSRPILDIVPQTYHERSALVFGVAEEVDILGEYFVK
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED22_XENLA
Sequence: MSQQRILPQSKETLLQSYNKRLKDDIKSIMDNFTEIIKTAKIEEEHQVSRSTQGEQDNYEMHVRSANIVRAGESLMKLVSDLKQFLILNDFPSVNESINQRNQQLRTLREECDKKLIALRDDIAIDLYELEEEYYSSSYSVCDPSDLPLCEVYWNRESTASSPEDLSVPLAPIMAEASTVTSQIHTPPHLNGHGAGMTEHT
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 22, Mediator complex subunit 22, Surfeit locus protein 5.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 22 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CUTS_STRCO
Sequence: MATTPAPPGAPPKPTWDPRSATPLPWLRPTIRIRLTLLYGGMFLIAGILLLSIIYLLAAQAVRTGNEPLYKIVDFTDLKVSSSTCPVVDNGGLSLSDFNAAISDCMDHQRKVALDNLLSRSLLALLGLAVIAFAFGYAMAGRVLSPLGRITRTARAVAGSDLSRRIELDGPDDELKELADTFDDMLERLQRAFTAQQRFVGNASHELRTPLAINRTLLEVHLSDPGAPVELQQLGKTLLATNERSELLVEGLLLLARSDNQIVERKPVDLAEVAGQAIDQVHAEAESKGVEVRGTREAAVVQGNGVLLERIALNLVQNAVRYNVAGQGWVEVATAVENGQAVLVVTNTGPVVPAYEVDNLFEPFRRLRTERTGSDKGVGLGLSIARSVARAHGGHISAQPREGGGLVMRVTLPV
What is the function of this protein?
Member of the two-component regulatory system CutS/CutR, involved in the regulation of copper metabolism.
What are the official names of this protein?
Sensor protein CutS.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RIR2_MONPV
Sequence: MEPILAPNPNRFVIFPIQYHDIWNMYKKAEASFWTVEEVDISKDINDWNKLTPDEKYFIKHVLAFFAASDGIVNENLAERFCTEVQITEARCFYGFQMAIENIHSEMYSLLIDTYVKDSNEKNYLFNAIETMPCVKKKADWAQKWIHDSAGYGERLIAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLLHPPSEETVRFIITNAVSIEQEFLTVALPVKLIGMNCEMMKTYIEFVADRLISELGFKKIYNVTNPFDFMENISLEGKTNFFEKRVGEYQKMGVMSQEDNHFSLDVDF
What is the function of this protein?
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis.  Allows virus growth in non-dividing cells.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase small chain, Ribonucleotide reductase small subunit, Ribonucleotide reductase subunit 2, RNR2.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
Protein: ACB1_BPSP8
Sequence: MTLNEVSEGLYVAAKFSELTLDALENLQRSLKVPNPVPREKFHSTICYSRVNIPYVVASGSFEVANSGHLEVWKTDDGSTLVLVLDSDYLSCRHMYARALGATHDFPDYTPHITLSYNVGPLTYKGEVQIPVVLDREYKEPLKLNWSADLK
What is the function of this protein?
Counteracts the host CBASS antiviral defense system.  Phosphodiesterase that enables metal-independent hydrolysis of the host cyclic di- and trinucleotide CBASS signals such as 3'3'-cGAMP, 3'3'cUA, and 3'3'3'-cAAA (PubMed:35395152).  Does not cleave cGG or cA4 (By similarity).  Besides evasion of the CBASS system, might also enable evasion of the type III CRISPR systems that use cA3 signals (By similarity).
What are the official names of this protein?
Anti-CBASS protein Acb1, Acb1, Gene product 57B, gp57B.
What is the protein family that this protein belongs to?
Belongs to the anti-CBASS protein Acb1 family.
Protein: B1_HHV6Z
Sequence: MQKNMKTKKTKKRGRKEGNTPETERRMEPARSRTSAIPSGLRRRSGPSTPLRPGPEVRHAPTWRTASATTADSHRISPPYTPSSRGRHIHTRGARTRTRETSAAEINGVYARAVTRKTKRSETIDRLLLSVLPGHGPHASLRSHLRARSALRPPPDPPR
What are the official names of this protein?
Protein B1.
Protein: CINAL_ECOLC
Sequence: MLKVEMLSTGDEVLHGQIVDTNAAWLADFFFHQGLPLSRRNTVGDNLDDLVTILRERSQHADVLIVNGGLGPTSDDLSALAAATAKGEGLVLHEAWLKEMERYFHERGRVMAPSNRKQAELPASAEFINNPVGTACGFAVQLNRCLMFFTPGVPSEFKVMVEHEILPRLRERFSLPQPPVCLRLTTFGRSESDLAQSLDTLQLPPGVTMGYRSSMPIIELKLTGPASEQQAMEKLWLDVKRVAGQSVIFEGTEGLPAQISRELQNRQFSLTLSEQFTGGLLALQLSRAGAPLLACEVVPSQEETLAQTAHWITERRANHFAGLALAVSGFENEHLNFALATPDGTFALRVRFSTTRYSLAIRQEVCAMMALNMLRRWLNGQDIASEHGWIEVVESMTLSV
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: PURQ_CHLTE
Sequence: MADVTVGIVVFPGSNCDHDTEYAVASFPGVKPVMLWHNDHDLKGCDAVILPGGFSYGDYLRCGAIARFSPIMREVIDFAGKGRPVLGICNGFQVLVECGLLEGALIRNAGRRFVSRQTTISVANNATIFTDRYQKGEVLRVPVAHGEGNYYASPETIESLESNGQVVFRYTDAWGNATAEANFNGSMNNIAGIVNKQGNVLGLMPHPERASEKLLGSEDGRRLFESLFAHLAGA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISY1_NEUCR
Sequence: MARNSEKAQSMLFRFREAQAADLGIIDAGRTRRPRSITEQDSIPACEKWRGQVLKEISRKVSRIQDPALSDYQIRDLNDEINKLMREKHMWEVQIRNLGGPNYMRSGGKVYDEAGREIPGGGRGYKYFGRARELPGVKELFEAAARAKQDDEKPLETRDDLRKQVDAAYYGYAPDEEDEKLLAYEAARERQAFENLAKAAAGLEPPPGWEPLPEWELPTMDEVAQELIDRRRRRLLDQL
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor isy1, mRNA-splicing protein 7.
What is the protein family that this protein belongs to?
Belongs to the ISY1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: 3SL2_DENAN
Sequence: RICYSHKASLPRATKTCVENSCYKMFIRTSPDYISDRGCGCPTAMWPYQTACCKGDRCNK
What is the function of this protein?
This specific blocker of the L-type calcium channel (Cav1/CACNA1) is a smooth muscle relaxant and an inhibitor of cardiac contractions.
What are the official names of this protein?
Toxin C10S2C2.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. L-type calcium blocker sub-subfamily.
Protein: UBP12_DANRE
Sequence: MEILMTVSKFASFCTMGANASALEKEIGSEQFPVNEHYFGLVNFGNTCYCNSVLQALYFCRPFREKILAYRSQPRRKENLLTCLADLFHSIANQKRKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADLLQEERKQDKQNGKLANGTLDSQNNNSTPPSTTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMRVKKLPMILALHLKRFKYMEQLQRYTKLSYRVVFPLELRLFNTSGDATNPERLYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSEISKNSESGYILFYQSRD
What is the function of this protein?
Deubiquitinating enzyme.  Has almost no deubiquitinating activity by itself and requires the interaction with wdr48 to have a high activity.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 12A, Deubiquitinating enzyme 12A, Ubiquitin thioesterase 12A, Ubiquitin-specific-processing protease 12A.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP12/USP46 subfamily.
Protein: NANT1_ECOL6
Sequence: MSTTTQNIPWYRHLNRAQWRAFSAAWLGYLLDGFDFVLIALVLTEVQGEFGLTTVQAASLISAAFISRWFGGLMLGAMGDRYGRRLAMVTSIVLFSAGTLACGFAPGYITMFIARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGFLISGFSVGAVVAAQVYSLVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHGGKAPVRTMVDILYRGEHRIANIVMTLAAATALWFCFAGNLQNAAIVAVLGLLCAAIFISFMVQSTGKRWPTGVMLMVVVLFAFLYSWPIQALLPTYLKTDLAYDPHTVANVLFFSGFGAAVGCCVGGFLGEWLGTRKAYVCSLLASQLLIIPVFAIGGANVWVLGLLLFFQQMLGQGISGILPKLIGGYFDTDQRAAGLGFTYNVGALGGALAPILGALIAQRLDLGTALGSLSFSLTFVVILLIGLDMPSRVQRWLRPEALRTHDAIDGKPFSGAVPFGSAKNDLVKTKS
What is the function of this protein?
Catalyzes the proton-dependent transport of sialic acid.
What are the official names of this protein?
Sialic acid transporter NanT 1, Sialic acid permease 1, Sialic acid/H(+) symporter 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GALE_DROME
Sequence: MAPPTVLVTGGAGYIGSHTVLEMLNAGYNVICVDNLCNAYSSGAKLPEALSRVQEITGKKVNFYRVDITDREQVRSVFQEHKIDMVAHFAALKAVGESCRIPLQYYHNNMTGTNVLLEAMADNNVFKFVYSSSATVYGEPKFLPVTEEHPTGNCTSPYGKTKYFTEEILKDLCKSDKRWAVVSLRYFNPVGAHISGRIGEDPNGEPNNLMPYIAQVAVGRRPSLSVYGSDFPTHDGTGVRDYIHIVDLAEGHVKALDKLRNIAETGFFAYNLGTGVGYSVLDMVKAFEKASGKKVNYTLVDRRSGDVATCYADATLADKKLGWKAERGIDKMCEDTWRWQSQNPNGYANK
What is the function of this protein?
Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine (PubMed:20519568, PubMed:22654673).  The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate.  It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited (PubMed:22654673).  Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.
What are the official names of this protein?
UDP-glucose 4-epimerase, Galactowaldenase, UDP-N-acetylgalactosamine 4-epimerase, UDP-GalNAc 4-epimerase, UDP-N-acetylglucosamine 4-epimerase, UDP-GlcNAc 4-epimerase, UDP-galactose 4-epimerase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Protein: PCFS5_ARATH
Sequence: MASNGSFSAQRNANAGTTMKRRNDNRGYGGGIGCYQEERNRYAPPQKRFRSQLQQQFRSGHNPLYHYGSNTNNNVSRVSSQSYNNYGVDVIASNSSFALPNNDSNTNNYQKPFVVYGNPNPQIVPLPLPYRKLDPLDSLPQWVPNSTPNYPVRSSNFVPNTPDFTNVQNPMNHSNMVSVVSQSMHQPIVLSKELTDLLSLLNNEKEKKTSEASNNDSLPVGLSFDNPSSLNVRHESVIKSLYSDMPRQCTSCGVRFKCQEEHSKHMDWHVRKNRSVKTTTRLGQQPKKSRGWLASASLWLCAPTGGGTVEVASFGGGEMQKKNEKDQVQKQHMVPADEDQKNCALCVEPFEEFFSHEADDWMYKDAVYLTKNGRIVHVKCMPEPRPAKDLREPSRVMSVTVPSVAKAILC
What are the official names of this protein?
Polyadenylation and cleavage factor homolog 5.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACP_EXISA
Sequence: MTKEQILVDVQEAVAEKLGKDVSEITAEKSFKDDLGADSLEVMEMVMDLEDKFDITIEDEDAEKLATVGDVVAYIETKL
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECTC_TERTT
Sequence: MIVRNLTEARDSNRRIVSPDGNWESTRMLLKDDKMGFSFHITTIYKGADFRMHYQNHLESVYCVRGRGEVETLADGKKYPIEPGTLYILDKHDEHMLRAFEEMEMACVFNPPLNGTEVHNAEGAYELNAEAL
What is the function of this protein?
Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.
What are the official names of this protein?
L-ectoine synthase, N-acetyldiaminobutyrate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the ectoine synthase family.
Protein: LOLD_AROAE
Sequence: MSEATNEPVLACEGLSKTFREGADALQVLDGVTLAVARGERIAIVGASGSGKSTLLHLLGGLDVPSAGAVRLHGRDFSRMSDAERGRVRNEALGFVYQFHHLLPEFSALENVAMPLYIRRMEREAANERAVAMLKEVGLGHRLDHAPGELSGGERQRAAIARALVTQPACVLADEPTGNLDRRTAQSVFDLMLSLNERLATSFIIVTHDEQLAGRAQRTLRLDDGRLA
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UREG_ACIBC
Sequence: MTERSPLRVGIGGPVGSGKTALTLNLCRALRDKYNMAVVTNDIYTKEDSNFLTRNEAMSPDRIVGVETGGCPHTAIREDASINLAAIDDLCEKFDGLELIIIESGGDNLAATFSPELSDLTLYVIDVAGGEKIPRKGGPGITKSDLLIINKTDLAPMVGANLDVMDQDAKRMRGEKPFLFSNMKTQDGLEEIIQFIEKQGLFKA
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7L_EDWI9
Sequence: MTQPVTPTIFTVSRLNQTVRQLLELEMGQIWLSAEISNLSQPASGHWYFTLKDDKAQVRCAMFRNSNRRVTFRPQNGQQVLVRASITLYESRGDYQLIAESMQPAGDGLLQQQFEALKQRLQAEGLFDVGHKQPLPSPARCVGVITSTSGAALHDVLHVLRRRDPALPVVIYPSAVQGGEAPGQLVRAIALANLRAECDVLIVGRGGGSLEDLWSFNDERVARAIFASHIPIVSAVGHETDVSIADFVADLRAPTPSAAAEVVSRNRDELLRRLLSQRQRLDMALDYTLARRRQRLQQLRHRLEQQHPQLRLARQQARLLSLHRRLEEAIDTQLRLAERRWRLGGERLQQRSPAHALRQQQYHLQQLSHRLESQLQRSVAARRERFGALCSRLEGMSPLATLARGFSVTQRDDGQLLRHREQVAPGDTLRTRLEDGWVESQVTATRPLTARRPRGTKGSA
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.