PharMolix/UniProtQA huggingface dataset:
Protein: ENO_BRUSU
Sequence: MTAIIDIVGREILDSRGNPTVEVDVVLEDGSFGRAAVPSGASTGAHEAVELRDGGSRYLGKGVEKAVEVVNGKIFDAIAGMDAESQLLIDQTLIDLDGSANKGNLGANAILGVSLAVAKAAAQASGLPLYRYVGGTNAHVLPVPMMNIINGGAHADNPIDFQEFMILPVGATSIREAVRYGSEVFHTLKKRLKDAGHNTNVGDEGGFAPNLKNAQAALDFIMESIEKAGFKPGEDIALGLDCAATEFFKDGNYVYEGERKTRDPKAQAKYLAKLASDYPIVTIEDGMAEDDWEGWKYLTDLIGNKCQLVGDDLFVTNSARLRDGIRLGVANSILVKVNQIGSLSETLDAVETAHKAGYTAVMSHRSGETEDSTIADLAVATNCGQIKTGSLARSDRTAKYNQLIRIEEELGKQARYAGRSALKLL
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: I2BPL_HUMAN
Sequence: MSAAQVSSSRRQSCYLCDLPRMPWAMIWDFSEPVCRGCVNYEGADRIEFVIETARQLKRAHGCFQDGRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAAAAAAAAVEQRSRFEYPPPPVSLGSSSHTARLPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASVASRRGTHGGLVTGLPNPGGGGGPQLTVPPNLLPQTLLNGPASAAVLPPPPPHALGSRGPPTPAPPGAPGGPACLGGTPGVSATSSSASSSTSSSVAEVGVGAGGKRPGSVSSTDQERELKEKQRNAEALAELSESLRNRAEEWASKPKMVRDTLLTLAGCTPYEVRFKKDHSLLGRVFAFDAVSKPGMDYELKLFIEYPTGSGNVYSSASGVAKQMYQDCMKDFGRGLSSGFKYLEYEKKHGSGDWRLLGDLLPEAVRFFKEGVPGADMLPQPYLDASCPMLPTALVSLSRAPSAPPGTGALPPAAPSGRGAAASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGPPPPPPPLGPHSNRTTPPESAPQNGPSPMAALMSVADTLGTAHSPKDGSSVHSTTASARRNSSSPVSPASVPGQRRLASRNGDLNLQVAPPPPSAHPGMDQVHPQNIPDSPMANSGPLCCTICHERLEDTHFVQCPSVPSHKFCFPCSRESIKAQGATGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDP
What is the function of this protein?
Probable E3 ubiquitin protein ligase involved in the proteasome-mediated ubiquitin-dependent degradation of target proteins (PubMed:29374064).  Through the degradation of CTNNB1, functions downstream of FOXF2 to negatively regulate the Wnt signaling pathway (PubMed:29374064).  Probably plays a role in the development of the central nervous system and in neuronal maintenance (Probable).  Also acts as a transcriptional regulator of genes controlling female reproductive function.  May play a role in gene transcription by transactivating GNRH1 promoter and repressing PENK promoter (By similarity).
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase IRF2BPL, Enhanced at puberty protein 1, Interferon regulatory factor 2-binding protein-like.
What is the protein family that this protein belongs to?
Belongs to the IRF2BP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IF4A1_PONAB
Sequence: MSASQDSRSRDNGPDGMEPEGVIESNWNEIVDSLDDMNLSESLLRGIYAYGFEKPSAIQQRAILSCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI
What is the function of this protein?
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.  In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
What are the official names of this protein?
Eukaryotic initiation factor 4A-I, eIF-4A-I, eIF4A-I, ATP-dependent RNA helicase eIF4A-1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. eIF4A subfamily.
Protein: RR14_OENGL
Sequence: MARKGLIQREKKREKLEQKYRLIRRSSKKEISTAPSLSEKWKIHGKLQSSPRNSAPTRLHRRCFSTGRPRANYRDFRLSGHILREMVHACLLPGATRSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YPT7_YEAST
Sequence: MSSRKKNILKVIILGDSGVGKTSLMHRYVNDKYSQQYKATIGADFLTKEVTVDGDKVATMQVWDTAGQERFQSLGVAFYRGADCCVLVYDVTNASSFENIKSWRDEFLVHANVNSPETFPFVILGNKIDAEESKKIVSEKSAQELAKSLGDIPLFLTSAKNAINVDTAFEEIARSALQQNQADTEAFEDDYNDAINIRLDGENNSCSC
What is the function of this protein?
Ypt/Rab-type GTPases are key regulators of membrane trafficking and intracellular vesicular transport.  They act as molecular switches that convert between GTP-bound and GDP-bound states, and regulate virtually all steps of membrane traffic from the formation of the transport vesicle at the donor membrane to its fusion at the target membrane.  In the GDP-bound state, Ypt proteins are predominantly cytosolic, solubilized through the interaction with a GDP dissociation inhibitor (GDI).  In the GTP-bound state, the proteins are membrane bound and interact with specific effector proteins that select cargo, promote vesicle movement, or verify the correct site of fusion (Probable).  YPT7 is involved in regulation of vesicular protein transport in exo- and endocytosis (PubMed:8308065).  Involved in homotypic vacuole fusion, the last step in the vacuole inheritance process, by interacting in its GTP-bound state on the donor membrane with the large multiprotein tethering complex termed HOPS on the acceptor membrane (PubMed:7489715, PubMed:11118206, PubMed:10725336, PubMed:10944212, PubMed:11210571, PubMed:19386605).  Involved in the regulation of transport steps from late endosomes to the vacuole, mediated by interaction in its GTP-bound state on the donor membrane with the large multiprotein tethering complex termed class C-Vps complex on the acceptor membrane (PubMed:8308065, PubMed:11062257, PubMed:21062894).  Involved in retromer assembly and cargo export, recognizing the cargo selection complex (CSC).  GTP-bound YPT7 recruits CSC to vacuolar membranes via retromer subunit VPS35 (PubMed:22593205).  Interacts with the HOPS complex subunit VPS39 independent of the HOPS complex at mitochondria-vacuole contact sites (vCLAMPs), providing a physical and metabolic interconnection between the endocytic pathway and mitochondria (PubMed:25026035).
What are the official names of this protein?
Ypt/Rab-type GTPase YPT7, Vacuolar morphology protein 4.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Late endosome. Vacuole membrane. Note=Localizes to sites of contact between the vacuole and mitochondria (vCLAMPs).
Protein: K2C7_HUMAN
Sequence: MSIHFSSPVFTSRSAAFSGRGAQVRLSSARPGGLGSSSLYGLGASRPRVAVRSAYGGPVGAGIREVTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKSAKSSRLPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSGGGIGLTLGGTMGSNALSFSSSAGPGLLKAYSIRTASASRRSARD
What is the function of this protein?
Blocks interferon-dependent interphase and stimulates DNA synthesis in cells.  Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
What are the official names of this protein?
Keratin, type II cytoskeletal 7, Cytokeratin-7, CK-7, Keratin-7, K7, Sarcolectin, Type-II keratin Kb7.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1257_METJA
Sequence: MKPVALVTTKPGFEPQLREELNKLPIKKKILWTPFRGILKVLSQNPYEFLNIIKENKNNLKFSLRIIPLEIGCQTDINEIKKAISFLINKKKEKLKNKSFVVRCNRRGNHEFTSEELERIIGEYVLENFKDLNLRVNLKDWDFKINIEILQDESYISIFQDEFNELVIEENIKNLKNLKRYIERPLNRSERKMQELMEKFPFIFENINCVVDIGSSPGGWAKMLSKKAKKVYAIDTGELKIKANNIIHIKKRAENVDFEKDINEEIDLITNDTNLYPDESLFLTLKFAKHLKTNGYIIHTLKARNLKTKKEDLEKVLKILSYYRNIKIFKIINLRANTKNELTLILKKV
What are the official names of this protein?
Uncharacterized protein MJ1257.
Protein: PYRG_RHOJR
Sequence: MPQSRTHSRTATKHIFVSGGVASSLGKGLTASSLGQLLTARGMRVTMQKLDPYLNVDPGTMNPFQHGEVFVTDDGAETDLDVGHYERFLDRDLSGQANVTTGQVYSTVIAKERRGEYLGDTVQVIPHITDEIKSRILAMSGPDLQGHQPDVVITEIGGTVGDIESQPFLEAARQVRHDVGRDNVFFLHVSLVPYLAPSGELKTKPTQHSVAALRNIGIQPDALILRCDREVPPALKNKIALMCDVDVDGCISTPDAPSIYDIPKVLHSEGLDAYVVRQLGLPFRDVDWTVWGNLLERVHQPRETVRIALVGKYVDLPDAYLSVTEALRAGGFANRSKVEISWVPSDACETEAGAQAALGDVDGVLIPGGFGIRGIEGKLGAIRYARHRKIPLLGLCLGLQCVVIEAARSVGLDDANSAEFEPETTHPVISTMADQEDVIAGEADLGGTMRLGAYPAVLTKGSVVARAYGSEEVSERHRHRYEVNNAYRDRIAKSGLRFSGTSPDGHLVEFVEYPADQHPFFVATQAHPELKSRPTRPHPLFAAFVDAALKHKLEERLPVDVHGEERAAVATDDELADSADRDEVASVDSAG
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: Y2020_NEIMB
Sequence: MQHDVYDYTAHTVSKNTVLQKTYRLLGFSFIPASAGAALAANAGFNFYAAFGSRWIGFAVVLAFFYGMIHFIEKNRYSNTGVTLLMVFTFGMGVLIGPVLQYALHIADGAKIVGIAAAMTAAVFLTMSALARRTRLDMNALGRFLTVGAVILMVAVVANLFLGIPALALTISAGFVLFSSLMIMWQVRTVIDGGEDSHISAALTLFISLYNIFSSLLNILLSLNGED
What are the official names of this protein?
Uncharacterized protein NMB2020.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIP1_ECTSH
Sequence: AERLDENSPEALALNYKHDGASVDHPSHAAGQKCINCLLYTDPSATEWGGCAVFPNKLVNANGWCTAYVARG
What is the function of this protein?
Specific class of high-redox-potential 4Fe-4S ferredoxins.  Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.
What are the official names of this protein?
High-potential iron-sulfur protein isozyme 1, HiPIP 1.
What is the protein family that this protein belongs to?
Belongs to the high-potential iron-sulfur protein (HiPIP) family.
Protein: TVA1_RABIT
Sequence: MFSASCSVTVVVLLITVRRTNGASVTQTEGPVILSEGSSLTLNCNYQTSYSGFLFWYVQYLHEGPQLLLQSTTENQRMEHQGFHATFVKKDSSFHLHKSSLQLSDSAVYYCALRRGASNKLTLGTGTLLKVELN
What are the official names of this protein?
T-cell receptor alpha chain V region RL-5.
Protein: SLFN5_HUMAN
Sequence: MSLRIDVDTNFPECVVDAGKVTLGTQQRQEMDPRLREKQNEIILRAVCALLNSGGGIIKAEIENKGYNYERHGVGLDVPPIFRSHLDKMQKENHFLIFVKSWNTEAGVPLATLCSNLYHRERTSTDVMDSQEALAFLKCRTQTPTNINVSNSLGPQAAQGSVQYEGNINVSAAALFDRKRLQYLEKLNLPESTHVEFVMFSTDVSHCVKDRLPKCVSAFANTEGGYVFFGVHDETCQVIGCEKEKIDLTSLRASIDGCIKKLPVHHFCTQRPEIKYVLNFLEVHDKGALRGYVCAIKVEKFCCAVFAKVPSSWQVKDNRVRQLPTREWTAWMMEADPDLSRCPEMVLQLSLSSATPRSKPVCIHKNSECLKEQQKRYFPVFSDRVVYTPESLYKELFSQHKGLRDLINTEMRPFSQGILIFSQSWAVDLGLQEKQGVICDALLISQNNTPILYTIFSKWDAGCKGYSMIVAYSLKQKLVNKGGYTGRLCITPLVCVLNSDRKAQSVYSSYLQIYPESYNFMTPQHMEALLQSLVIVLLGFKSFLSEELGSEVLNLLTNKQYELLSKNLRKTRELFVHGLPGSGKTILALRIMEKIRNVFHCEPANILYICENQPLKKLVSFSKKNICQPVTRKTFMKNNFEHIQHIIIDDAQNFRTEDGDWYGKAKFITQTARDGPGVLWIFLDYFQTYHLSCSGLPPPSDQYPREEINRVVRNAGPIANYLQQVMQEARQNPPPNLPPGSLVMLYEPKWAQGVPGNLEIIEDLNLEEILIYVANKCRFLLRNGYSPKDIAVLFTKASEVEKYKDRLLTAMRKRKLSQLHEESDLLLQIGDASDVLTDHIVLDSVCRFSGLERNIVFGINPGVAPPAGAYNLLLCLASRAKRHLYILKASV
What is the function of this protein?
May have a role in hematopoietic cell differentiation.
What are the official names of this protein?
Schlafen family member 5.
What is the protein family that this protein belongs to?
Belongs to the Schlafen family. Subgroup III subfamily.
Protein: PCYOX_ARATH
Sequence: MKDFPIAISLLFALLSPVLLPCSGDSTGGVEDDSPATVCIVGSGIGGSSVAHFLRNYSVSTGLNQAKILMFERHEIVGGRMRTVTVAGDTFEAGGSILHPKNYHVKDFVERFNLTVRLPTPIEESSAIGIWDGKRFVVKTFGSGTKFPFLDTIVSWVNDLYLFLRYGLSLLRMSSFIENTVDNFLKYYESLESRPIFDNVEGMLKWSGLYNLTKLTLQEKLSEAQLSPLLVNELVTVITRINYGQSVLISGLAGAVSLAGSGGGLWSVEGGNWQMAAKLINHSDVTLHLNEKIESISYLENHYELKSTKGNSYKCDVTVVATPLDEVDIQFSPTISIPKRELQHTHTTFVRGLLNPGYFGMKSLSDVPALVGTLEDPLIPFSCISILRKYSKTDMTYKIFTRQPASDSLLDELFSRRTETVRIDWGAYPKYHAPEVFAPFILDDHHLYYVNAFENAASTMETSAVAGENIARLIISRFMTKESLSSSDKRSCSSGLHSDS
What is the function of this protein?
Involved in the degradation of prenylcysteine.  Cleaves specifically the thioether bond of S-farnesyl-L-cysteine and has no activity with S-geranylgeranyl-L-cysteine.  Recognizes also N-acetyl-farnesylcysteine and may have a role in deprenylation of farnesylated proteins.
What are the official names of this protein?
Farnesylcysteine lyase.
What is the protein family that this protein belongs to?
Belongs to the prenylcysteine oxidase family.
What are the subcellular locations of this protein?
Lysosome.
Protein: DNLJ_SYNC1
Sequence: MDKAQRIRRYQQLCDELHRHSRLYYTYDRPEITDAEYDRLFRELLELEKAYPELVTAASPSLRVGASPLSQFTPVPHSRPMLSLENALTEDELYDFDARIRKLLASDAPVRYVCELKMDGVAVELVYRDGILSVGSTRGDGTTGEGITENLRTIPSIPLVLSGEAPALLEVRGEVYIDLDDFQKLNHEREEEGLQVFANPRNAAAGSLRQLDSAVTAKRPLKIFCYGIGQLSGEHPASHHSLLKCMHRWGLRVNLEHSRTLEGIEQVTDYFRQLQQRRDELPYEIDGMVVKVDDLALQRELGEKTRTPRWAIACKFPPRQAVTVVEDIVLQVGRTGAITPVAQLKPVEVSGVTVSRASLHNWDEIARLDVLIGDTVVVERAGDVIPDVVKVLTEHRNGQERSVPLPQSCPACGGPVVKLEGEVVPRCQEMSCPARLRESIKHFVARRAMDIDGLGERTIEQLLKRELIKSVADLYHLTKEDLLLCERLADKSAEKLLTAIAASKTRPLGRFLFALGIRHVGEHLASLLARQFGSLDALSHATREELLAIHEIGPQVADSVTDFFAKSRNREILAALQRAGVAPQAEEKRSGGPLTGKSFVFTGSLTRFSRKQAQEMVERLGGRASGSVSKKTDCVVAGEAAGSKLEKARQLNIQILSEEEFLQMIDTLEEA
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: Y840_JANMA
Sequence: MPSFDTVSEANMVEVKNAVDQAGKEISTRFDFKGSDARVEQKDRDLTAYADSEFQLNQVLDVLTGKLVKRNVDVRFLDRGKIEKIGGDKVKQVIKIKNGIETEAAKKIVRIIKDSKMKVQASIQGDAVRVTGAKRDDLQAAMAMLRKEVADLPLEFNNFRD
What are the official names of this protein?
UPF0234 protein mma_0840.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: RAC8_ARATH
Sequence: MASSASKFIKCVTVGDGAVGKTCMLICYTSNKFPTDYIPTVFDNFSVNVVVEGITVNLGLWDTAGQEDYNRLRPLSYRGADVFVLAFSLISRASYENVFKKWIPELQHFAPGVPIVLVGTKMDLREDRHYLSDHPGLSPVTTSQGEELRKHIGATYYIECSSKTQQNVKAVFDAAIKVVIKPAVKQKEKKKKQKPRSGCLSNILCGKN
What is the function of this protein?
Acts as a negative regulator of abscisic acid (ABA) responses.
What are the official names of this protein?
Rac-like GTP-binding protein ARAC8, GTPase protein ROP10.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor.
Protein: FRSA_ECOK1
Sequence: MTQANLSETLFKPRFKHPETSTLVRRFSHGAQPPVQSALDGKTIPHWYRMINRLMWIWRGIDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWATQAMVWQQKACAEEDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEAAQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYFAPRGIAMLTIDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGANVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEALRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFNPVYRNFDKGLQEITDWIEKRLC
What is the function of this protein?
Catalyzes the hydrolysis of esters.
What are the official names of this protein?
Esterase FrsA.
What is the protein family that this protein belongs to?
Belongs to the FrsA family.
Protein: PGRP1_HOLDI
Sequence: MKLATITFFLLTEIFFYISYAEATRSGPDLCPTIISKRDWGGNAALRVGYTSKPLERVVIHHTVTPECANEARCSSRMVSMQNYHMDELGYDDISYNFVIGGDGRVYEGVGWHKKGSHSPGWDSQSIGIAFIGDFTNKLPSREMLDAAKDLIVCAIELGELTRGYKLLGARNVKATKSPGDKLYREIQNWEGFTRRP
What is the function of this protein?
Peptidoglycan-recognition protein probably involved in innate immunity by binding to peptidoglycans (PGN) of bacteria and activating the prophenoloxidase (proPO) cascade immune response.  Binds to 1,3-beta-D-glucan and PGN.
What are the official names of this protein?
Peptidoglycan-recognition protein 1, Hd-PGRP-1.
What is the protein family that this protein belongs to?
Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SUFS_YERPB
Sequence: MNFPIERVRADFPLLSRQVNGQPLVYLDSAASAQKPQAVIDKELHFYRDGYAAVHRGIHSLSAEATQQMEAVRTQVADFIHAASAEEIIFVRGTTEAINLVANSYGRHFLAAGDSIIITEMEHHANIVPWQMLAQDLGVEIRVWPLTATGELKITALAALIDDTTRLLAVTQVSNVLGTVNPIKDIVAQAKAAGLVVLVDGAQAVMHQPVDVQALGCDFYVFSGHKLYGPSGIGILYGKSALLQQMPPWEGGGAMIKTVSLTQGTTFADAPWRFEAGSPNTAGIMGLGAAIDYVTELGLLPIQQYEQSLMHYALAQLSQIKSLTLYGPTERAGVIAFNLGQHHAYDVGSFLDQYGIAIRTGHHCAMPLMAFYQVPSMCRASLALYNTREDVDRLVAGLQRIEKLLG
What is the function of this protein?
Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation.  Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine.  Selenocysteine lyase activity is however unsure in vivo.
What are the official names of this protein?
Cysteine desulfurase, Selenocysteine beta-lyase, SCL, Selenocysteine lyase, Selenocysteine reductase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KP4T_UMV4
Sequence: MQIINVVYSFLFAAAMLPVVHSLGINCRGSSQCGLSGGNLMVRIRDQACGNQGQTWCPGERRAKVCGTGNSISAYVQSTNNCISGTEACRHLTNLVNHGCRVCGSDPLYAGNDVSRGQLTVNYVNSC
What is the function of this protein?
This protein is lethal to sensitive cells of the same or related species.  It specifically inhibits voltage-gated calcium channels.  It inhibits cell growth and division by blocking calcium import.
What are the official names of this protein?
KP4 killer toxin, Fungal toxin KP4, Killer protein 4.
What are the subcellular locations of this protein?
Secreted.
Protein: VATE_HALVD
Sequence: MSLDNVVEDIRDEARARAEDIRQDGQEQADEIVAEAEADAEELLESRKADVEQQLEREREQALSSAKLEAKQARLSARRDVLQRVREQVERELAELEGDRREELTRSLLDAAAVEFEDADEVSVYGRADDEELLSSILEDYDGYEFAGERDCLGGVVVEGSNSRVRVNNTFDSVLDTVWEDNLKEVSARLFDDQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: COX2_DROAT
Sequence: MSTWANLGLQDSASPLMEQLIFFHDHALLILVMITVLVGYLMFMLFFNSYVNRFLLHGQLIEMIWTILPAIILLFIAMPSLRLLYLLDEINEPSITLKSIGHQWYWSYEYSDFNNVEFDSYMIPTNELANDGFRLLDVDNRIVLPMNSQIRILVTAADVIHSWTVPALGVKVDGTPGRLNQTNFFINRPGLFYGQCSEICGANHSFMPIVIESVPVNYFIKWISNSVNS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y3844_POLSJ
Sequence: MTIRTLTPIEARVLGTLMEKARTVPDSYPLSLNALVSGCNQKTSRDPLMEVNDDEARAAIDSLKAQSLVFEGSSSRVPRFEHNFQRAAGVNEPQAMVMGLLMLRGPQTAAELRTNGERWYRFADSAAVEAVLLELQQRGEDGGQATVQKLPRAAGAREQRWVHLLCGEPDIQALMASAPTTAEAEGLLARVTALENTLARLKADNAQLRSHVLNISEQLGIALPETLDDAHDHSPN
What are the official names of this protein?
UPF0502 protein Bpro_3844.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: PSBL_PROMM
Sequence: MEQNPNPNNLPAELNRTSLYLGLLLVFVTAVLFTSYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: SODC_POLSN
Sequence: MVKAVCVLRGDSKITGIVNFEQESDSSPTTISWEISNHDADAKRGFHITPFGDNTNGCTSAGPHFNPHGKTHGNVTDENRHVGDMGNIETDCDGNSKGSIKDKLIKLIGPHSVIGRTVVIHAGTDDLGKGGNDESLKTGNAGPRPACGVIGVAN
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAS2_YEAST
Sequence: MPLNKSNIREYKLVVVGGGGVGKSALTIQLTQSHFVDEYDPTIEDSYRKQVVIDDEVSILDILDTAGQEEYSAMREQYMRNGEGFLLVYSITSKSSLDELMTYYQQILRVKDTDYVPIVVVGNKSDLENEKQVSYQDGLNMAKQMNAPFLETSAKQAINVEEAFYTLARLVRDEGGKYNKTLTENDNSKQTSQDTKGSGANSVPRNSGGHRKMSNAANGKNVNSSTTVVNARNASIESKTGLAGNQATNGKTQTDRTNIDNSTGQAGQANAQSANTVNNRVNNNSKAGQVSNAKQARKQQAAPGGNTSEASKSGSGGCCIIS
What is the function of this protein?
The S. cerevisiae Ras proteins modulate the activity of the adenylate cyclase catalytic subunit and therefore affect the biosynthesis of cyclic-AMP.
What are the official names of this protein?
Ras-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: Y415_METJA
Sequence: MKRLKLLGGVMLFAIVSLMVCGCMVVFPKKYPDVLYKEYDVIKIENRTINGVKTAIVYQVKTEIGARSSPYSLDADSKKDIGAITYYVFKNTDVDEVQIICYYAGGGGLQPYYKFKIKRRDAELSGLLNVSEKELPSATLYYIDKLISLGDLWINDRLPVNG
What are the official names of this protein?
Uncharacterized protein MJ0415.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.