PharMolix/UniProtQA huggingface dataset:
Protein: SYS_CLOBJ
Sequence: MLDLKRIRNNSNEIKEALNNRGEKFDVTVIDEVLKLDEERRNILVKVEVLKSKRNKVSSEVPKLKKEGKDVSNIVAEMKNLSEEIKGFDVTLAKIDEKIQYIMLRIPNIPNPQVPDGETDEDNIEIRNWLEPTKFDFEPKAHWDIGTNLNILDFERAGKVTGSRFTFYKGLGARLERAVISYFLDTHTEKHDYTEILPPYMVNRTSMIGTGQLPKFEEDAFKISEDDYFLIPTAEVPVTNLYRDEILKGDELPLKHVAYSACFRSEAGSAGRDTRGLVRQHQFNKVELVKFTKPEQSYEELEKLTNDAETVLKELGIPYRVVRICKGDLGFTAALKYDLEVWMPSYNRYVEISSCSNFEDFQARRANIRYKEDAKAKPQYVHTLNGSGVAIGRTVAAILENYQSEDGSVTIPEVLRPYMGGREVIK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GFA_ASPTN
Sequence: MNPILHPLIDNGITPGDPNFAGGNLYCKCPQNKVTVTLKSNVAHNHACGCSKCWKPTGALFSVVGVVPRENLSVTANGDKLHVVDKNAVIQRNACRQCGVHMFGRIETEHPFKGLDFVHVELSDTRGWQEPQFAGFVSSIIEQGFDPSKMETVRSRFKAVGLETYDSLSPPLMDTIAAYTARKNGKLSARL
What is the function of this protein?
Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.
What are the official names of this protein?
Putative glutathione-dependent formaldehyde-activating enzyme, S-(hydroxymethyl)glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the Gfa family.
Protein: YRKA_BACSU
Sequence: MTTINLIIFTLLIVLTAFFVATEFAIVKIRSSKIDQLILEGKKGAISAKKVITHLDEYLSACQLGITVTALGIGWVGESTFEVILHPLFAHFHVSETVSHVLILVIAFVMATFLHVVVGELAPKTLAIQKAETITLLTAKPIIWFYRILFPFIWFLNGSARFIVGLFGLKPASEHELAHSEEELRILLSESYKSGEINQNELKYVNNIFEFDERIAKEIMIPRREIVAISSEDSYETIVKIIKTESYTRYPVLNGDKDSIIGFINAKEFLSAYIDTDQKIKEDFKLENHINPVIHVIESVPIHDVLVKMQKERTHIAILVDEYGGTSGLVTAEDILEEIVGEIRDEFDKDEVPNIRKVNDNHYILDSKVLIEDVNDLLGTTLASDEVDTIGGWFMTQQIDAAVGSVIEADGYIFKVHETVGRHINYLEIVRKKE
What are the official names of this protein?
UPF0053 protein YrkA.
What is the protein family that this protein belongs to?
Belongs to the UPF0053 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DAAF3_HUMAN
Sequence: MTTPAGSGSGFGSVSWWGLSPALDLQAESPPVDPDSQADTVHSNPELDVLLLGSVDGRHLLRTLSRAKFWPRRRFNFFVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLEVWGNALLRPPVAAFVRAQADLLAHLVPEPDRLEEQLPWLSLRALKFRERDALEAVFRFWAGGEKGPQAFPMSRLWDSRLRHYLGSRYDARRGVSDWDLRMKLHDRGAQVIHPQEFRRWRDTGVAFELRDSSAYHVPNRTLASGRLLSYRGERVAARGYWGDIATGPFVAFGIEADDESLLRTSNGQPVKTAGEITQHNVTELLRDVAAWGRARATGGDLEEQQHAEGSPEPGTPAAPTPESFTVHFLPLNSAQTLHHKSCYNGRFQLLYVACGMVHLLIPELGACVAPGGNLIVELARYLVDVRQEQLQGFNTRVRELAQAAGFAPQTGARPSETFARFCKSQESALGNTVPAVEPGTPPLDILAQPLEASNPALEGLTQPLQGGTPHCEPCQLPSESPGSLSEVLAQPQGALAPPNCESDSKTGV
What is the function of this protein?
Required for the assembly of axonemal inner and outer dynein arms.  Involved in preassembly of dyneins into complexes before their transport into cilia.
What are the official names of this protein?
Dynein axonemal assembly factor 3.
What is the protein family that this protein belongs to?
Belongs to the DNAAF3 family.
What are the subcellular locations of this protein?
Cytoplasm. Dynein axonemal particle.
Protein: NHAA_BART1
Sequence: MSDLSSNRLPNRASRVTNQALSAIERFLHIEALSGIVLLLAAASALIFANSQYAALYESFWHTPLGFNLGHFTLSWDLHFWVNDALMTIFFLVAGMEIRREIHEGALADFKQAILPIVAAIGGVCVPAIIYFIFNFNEGHIHGWAVPTATDIAFALGILALLGKKIPSNLHIILLSLAIIDDIIAVLIIAFFYSTNIDPSGLLIAGGGIALVLFFQWIGLASAWLYILPGAIIWWGLMVTGVHPSLAGVILGMMTPVFPTRTLVAPLTMLSNAMQILQEKNTKTDLHHISTALKKMRKGQRAMIAPVTRIQKALHPWVAYGIMPVFAFANAGVSFANFDLSSGKSFLIVFGVVIGLFVGKPLGIITASYLAVKSGLCRLPPQMTWAGILLIGFLAGIGFTMSIFVSMLAFKDIILLDAAKIGVLCGSGLSALIGLGYGFIYIKRNKDIPHSSE
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ECCB4_MYCTU
Sequence: MPSPATTWLHVSGYRFLLRRIECALLFGDVCAATGALRARTTSLALGCVLAIVAAMGCAFVALLRPQSALGQAPIVMGRESGALYVRVDDVWHPVLNLASARLIAATNANPQPVSESELGHTKRGPLLGIPGAPQLLDQPLAGAESAWAICDSDNGGSTTVVVGPAEDSSAQVLTAEQMILVATESGSPTYLLYGGRRAVVDLADPAVVWALRLQGRVPHVVAQSLLNAVPEAPRITAPRIRGGGRASVGLPGFLVGGVVRITRASGDEYYVVLEDGVQRIGQVAADLLRFGDSQGSVNVPTVAPDVIRVAPIVNTLPVSAFPDRPPTPVDGSPGRAVTTLCVTWTPAQPGAARVAFLAGSGPPVPLGGVPVTLAQADGRGPALDAVYLPPGRSAYVAARSLSGGGTGTRYLVTDTGVRFAIHDDDVAHDLGLPTAAIPAPWPVLATLPSGPELSRANASVARDTVAPGP
What is the function of this protein?
An ATPase (By similarity).
What are the official names of this protein?
ESX-4 secretion system ATPase EccB4, ESX conserved component B4, Type VII secretion system protein EccB4, T7SS protein EccB4.
What is the protein family that this protein belongs to?
Belongs to the EccB family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CYB_CTELA
Sequence: MTNTRKSHPLIKIMNHSFIDLPAPSNISAWWNFGSLLGVCLGLQILTGLFLAMHYTADTTTAFSSVTHICRDVNYGWLIRYMHANGASMFFIFLYLHIGRGIYYGSYTFTNTWNIGVLLLLAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGPTLVEWIWGGFSVDKATLTRFFAFHFILPFMITAMVMIHLLFLHETGSNNPSGVNSDSDKIPFHPYYTIKDVLGILFMMITLMSLVMFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILTLFPILHSSKQRSMSFRPLSQCLMWMLVANLLILTWIGGQPVEHPFITIGQLASVTYFFTILILMPSTALMENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YCF3_CYACA
Sequence: MPRSQKNDNFIDKTFSIIADLIVKILPTNKESKEAFYYYKDGMAAQSEGEYAEALACYYQALKIEKDPMDKSFILYNIGLIQASNGQHARALEYYHESLKFNPNLVQALNNIAVIYHYYGNKLFEQSKLQEAKLMFDKASNYWRKAIKLAPYNYIEAQNWLKITGRITEDIML
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: GLT1_ORYSJ
Sequence: MSAAQGMAYKLRTDAAPTGAGRRARRSHSSVAAPYRAARLVQGGVSIEGGLVGGCQLTEERVAARPPRAAARDAEPVRPLSTLPESSIGLYDPSRERDSCGVGFVAELSGDYKRATVNDALEMLERMAHRGACGCEKNTGDGAGILVALPHNFFREVTKDAGFELPQPGEYAVGMVFLPIDEKRRERSKAEFQKVAESLGHVILGWRRVPTDNSDLGESALQTEPVIEQVFLTKSSSSEADFEQQLYILRRLSILSIRAALNLRRGGKRDFYMCSLSSRTIVYKGQLKPCQLKGYYYADLGHENFTSYMALVHSRFSTNTFPSWDRAQPMRVLGHNGEINTLKGNKNWMKAREGLLECEKLGLTKDQFSKILPIVDATSSDSGAFDGVLELLIRGGRSLPEAVMMMIPEAWQNDVNMEPEKKALYEFLSALMEPWDGPALISFTDGRYLGATLDRNGLRPGRFYVTHSGRVVMGSEVGVVDVPSKDVLRKGRLNPGMMLLVDFENHTVVDDEALKAQYSKAHPYGEWLKRQKIYLKDIVESVPETERVAPGISGSLTQKNEKKEHAGVNGIVTPLKAFGYTVEALEMLLLPMAKDGVEALGSMGNDTPLAVMSNREKLTFEYFKQMFAQVTNPPIDPIREKIVTSMECMIGPEGDLLETTEKQCNRLALEGPLVSIDEMEAIKKMNYRGWRSKVLDITYPKKSGRKGLEETLDRICTEARGAIKKGYTVLVLSDRGFSSDRVAVSSLLAVGAVHQHLVANLERTRVGLLVESAEPREVHHFCTLVGFGADAVCPYLAIEAIWCLQNDGKIPPNGDGKPYSKEELVKKYFYASNYGMMKVLAKMGISTLASYKGAQIFEALGLSSEVIRKCFDGTPSRIEGATFEMLARDALRLHELAFPSRAPPPGSADAKALPNPGDYHWRKNGEVHLNDPLAMAKLQEAARVNSRAAYKEYSRRIQELNKTCNLRGMLKFKDTADMISVDEVEPASEIVKRFVTGAMSYGSISLEAHTALAMAMNKLGGKSNTGEGGEQPSRMEPLANGSMNPKRSAIKQVASGRFGVSSYYLTNADELQIKMAQGAKPGEGGELPGHKVIGDIAVTRHSTAGVGLISPPPHHDIYSIEDLAQLIHDLKNSNPRARISVKLVSEAGVGVVASGVVKGHADHVLISGHDGGTGASRWTGIKNAGLPWELGLAETHQTLVANGLRGRAILQTDGQLKTGKDVAVACLLGAEEFGFSTAPLITLGCIMMRKCHTNTCPVGIATQDPVLREKFAGEPEHVINFFFMLAEELREIMSQLGFRTITEMVGRSDMLEVDPEVVKSNEKLENIDLSLILKPAAEIRPGAAQYCVEKQDHGLDMALDNKLIALSKAALEKEVRVFIETPIQNTNRAVGTMLSHEVTKRYHMKGLPAGTIHVKLTGSAGQSLGAFLCPGITLELEGDSNDYVGKGLSGGKIVVYPPRDSTFIPEDNIVIGNVALYGATIGEAYFNGMAAERFCVRNSGAQAVVEGIGDHGCEYMTGGTVVILGKTGRNFAAGMSGGIAYVYDIDGKFSVRCNHELVDLYHVEEEEDITTLKMMIEQHRLNTGSVVARDILSNFDTLLPKFVKVFPRDYKRVLDNMKAEKAAAKLAKEPKISNGVSVTTKKVQPEQSTNRPTRVSNAKKYRGFISYERESISYRDPNERVKDWKEVAIESVPGPLLNTQSARCMDCGTPFCHQESSGAGCPLGNKIPEFNELVHQNRWREALDRLLETNNFPEFTGRVCPAPCEGSCVLGIIENPVSIKSIECAIIDKGFEEGWMVPRPPLQRTGKKVAIIGSGPAGLAAADQLNKMGHFVTVFERADRIGGLMMYGVPNMKTDKIEIVQRRVNLMAEEGITFVVNANVGSDPLYSIERLRSENDAVILACGATKPRDLGIPGRELSGVHFAMEFLHANTKSLLDSNLEDGRYISAKGKKVVVIGGGDTGTDCIGTSIRHGCTSIVNLELLTKPPSKRAADNPWPQWPRIFRVDYGHQEASSKFGNDPRTYEVLTKRFIGDENGNVKALEVVRVKWEKVDGRFQFKEIEGSNETIEADLVLLAMGFLGPEATIAEKLGLEKDNRSNFKAQFGNFATSVDGIFAAGDCRRGQSLVVWAITEGRQAAAAVDKYLSRNEQDAAEDITPSGAGFVQPVAA
What is the function of this protein?
Involved in glutamate biosynthesis and plays a major role in the primary ammonium ions assimilation in seedling roots.  May be involved in the reutilization of glutamine in developing organs.  Plays a role in the development of tillers.
What are the official names of this protein?
Glutamate synthase 1 [NADH], chloroplastic, NADH-dependent glutamate synthase 1, NADH-GOGAT 1.
What is the protein family that this protein belongs to?
Belongs to the glutamate synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: THIO_RICBR
Sequence: MASNVTDKSFEEEVLKSDLPVLVDFWAEWCSPCRMLTPIIEEISKDLESKVKVLKMNIDENPEIPSKYGIRSIPTVMLFKNGEQKDTKVGLHQKNSLIEWINNNI
What is the function of this protein?
Component of the thioredoxin-thioredoxin reductase system.  Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity).
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: CYVB_VIOCT
Sequence: GSIPCAESCVYIPCITGIAGCSCKNKVCYYN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cyclotide vico-B.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: DERL2_DICDI
Sequence: MAQPFEDWYKNLPIVTKIYMTGCVVTSVSVYLGLVGPLRLYLNFPLVFGKYEFWRLFTNFFFYDEIGMNFFFHMYFLVRHSRLLEESSFRGRSADYLFMWIFGSFLLLIMDAFLFYTKIVTKVLFLAPSIAFMVIYVWSRRNPNMHISFLGLFTFSAPYLPWVILIMGYLFNHDLTTDLLGAVAGHAYYFLEDAYPLISNRRLLKTPGFLKNLMDGQEQPIVDAHQQQEVQQAQQQEVQQPVQNFLNEDDLDQQ
What is the function of this protein?
May be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins.  May also be involved in endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the endoplasmic reticulum and reroutes them to the cytosol for proteasomal degradation.
What are the official names of this protein?
Probable derlin-2 homolog.
What is the protein family that this protein belongs to?
Belongs to the derlin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y3123_CHRVO
Sequence: MAGHSKWANIQHRKGRQDAKRGKIFTRLIKEITVAAKMGGGDANMNPRLRLAVDKAKAESMPKDNIENAIKRGTGQLDGVDYVECRYEGYGIAGAAVMVDCLTDNKTRTVADVRHAFSKYGGNMGTDGCVAFQFKHCGYLVFAPGVDEDALMEAALEAGAEDVVSNDDGSIEVITGPYEFSDVKDALEAKGFKSEMGEVTMRAENETELSGDDAVRMQKLLDALEDLDDVQDVYTSAVIGE
What are the official names of this protein?
Probable transcriptional regulatory protein CV_3123.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCX1_CHLRE
Sequence: MICFKQQKITSLFVSLILLLTTILICWFCVLSPKVNGTNSPIEVNVYNPIPLAVMRGGIPLPGMPPVPTATPSLPRSGFTSSAKKIKESRKQKSTALQAVKDQYILRVARL
What are the official names of this protein?
Uncharacterized 12.2 kDa protein in 16S rRNA region.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SSTT_SHESM
Sequence: MKQESSFLAKLANGSLVLQILVGIIAGVSLASFSHEAAKQVAFLGSLFVGALKAIAPILVFILVASSIANQKKNTQTNMRPIVVLYLFGTFAAALTAVLLSMMFPTNLVLVAGVEGTSPPQGIGEVLNTLLFKLVDNPVNALMTGNYIGILAWGVGLGLALHHASDSTKQVFADVSHGISQMVRFIIRLAPIGIFGLVAATFAETGFAAIAGYAKLLAVLLGAMAIIALIVNPLIVYVKIKRNPYPLVIRCLRESGVTAFFTRSSAANIPVNMALCEKLKLHEDTYSVSIPLGATINMGGAAITITVLTLAAAHTLGIQVDLLTALLLSVVAAISACGASGVAGGSLLLIPLACSLFGISNDVAMQVVAVGFIIGVIQDAAETALNSSTDVIFTAAACEAAENKAKLG
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISCR_PECAS
Sequence: MRLTSKGRYAVTAMLDVALHSQEGPVPLADISERQGISLSYLEQLFSRLRKNGLVASVRGPGGGYLLGKNANEIAVGMVISAVDESVDATRCQGRESCQGGDRCLTHTLWRDLSDRITDFLNNITLDELVNNKEVLNVADRQDTDTRRTANGRIQETINVNLRA
What is the function of this protein?
Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
What are the official names of this protein?
HTH-type transcriptional regulator IscR.
Protein: ENOXE_FRAAN
Sequence: MAAAPSESIPSVNKAWVYSEYGKTSDVLKFDPSVAVPEVKEDQVLIKVVAASLNPVDFKRALGYFKDTDSPLPTVPGYDVAGVVVKVGSQVTKFKVGDEVYGDLNEAALVNPTRFGSLAEYTAADERVLAHKPKDLSFIEAASLPLAIETAYEGLERAELSAGKSILVLGGAGGVGTHIIQLAKHVFGASKVAATASTKKLDFLRTLGVDLAIDYTKENIEDLPEKFDVVYDAVGETDKAVKAVKEGGKVVTIVGPATPPAIHFVLTSKGSVLEKLKPYLESGKVKPVLDPTSPYPFTKLVEAFGYLESSRATGKVVVYPIP
What is the function of this protein?
Enone oxidoreductase involved in the biosynthesis of 4-hydroxy-2,5-dimethyl-3(2H)-furanone (HDMF or furaneol), the key flavor compound in strawberries.  Can use both NADH and NADPH as the electron donor.
What are the official names of this protein?
2-methylene-furan-3-one reductase, Enone oxidoreductase, FaEO, Quinone oxidoreductase, FaQR.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
Protein: FRS1L_MOUSE
Sequence: MAGQPLRRPAWVPLLLRLLLAGIAACDASPADDSAGPGGRGPRGRARGDAGADEAVPRHDSSYGTFASEFYDLRYLSEEGYPFPTAPPVDPFAKIKVEDCGRTKGCFRYGKPGCNAETCDYFLSYRMIGADVEFELSADTDGWVAVGFSSDKKMGGDDVMACVHDDNGRVRIQHFYNVGQWAKEVQRNPARDEEGVFENNRVTCRFKRPVNVPRDETIVDLHLSWYYLFAWGPAIQGAITRHDIDSPPASERVVSIYKYEDIFMPSAAYQTFSSPFCLLLIVALTFYLLMGTP
What is the function of this protein?
Important modulator of glutamate signaling pathway.
What are the official names of this protein?
DOMON domain-containing protein FRRS1L, Ferric-chelate reductase 1-like protein.
What are the subcellular locations of this protein?
Cell membrane. Synapse.
Protein: COXX_BURL3
Sequence: MQSTLSQSPGSRFSQYMALTKPRVTQLAVFCAVIGMFLATPGMVPWHVLIGGTVGIWLLAGAAFAINCLVEQKIDAMMRRTAWRPSARGEITTPQILIFSAVLGSVGAWTLYTFTNPLTMWLTIATFVGYAVIYTLLLKPMTPQNIVIGGASGAMPPALGWAAVTGAVPGDAWILVLIIFVWTPPHFWVLALYRRKDYENAGLPMLPVTHGEKFTRLHILLYTVILFAVTLMPFISGMSGAVYLTSAVLLGAVFLAYAWKIHRDYSDELARKAFRYSIVYLSLLFAALLVDHYARPLLGV
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NIT1_MOUSE
Sequence: MLGFITRPPHQLLCTGYRLLRTPVLCTQPRPRTMSSSTSWELPLVAVCQVTSTPNKQENFKTCAELVQEAARLGACLAFLPEAFDFIARNPAETLLLSEPLNGDLLGQYSQLARECGIWLSLGGFHERGQDWEQNQKIYNCHVLLNSKGSVVASYRKTHLCDVEIPGQGPMRESNYTKPGGTLEPPVKTPAGKVGLAICYDMRFPELSLKLAQAGAEILTYPSAFGSVTGPAHWEVLLRARAIESQCYVIAAAQCGRHHETRASYGHSMVVDPWGTVVARCSEGPGLCLARIDLHFLQQMRQHLPVFQHRRPDLYGSLGHPLS
What is the function of this protein?
Catalyzes the hydrolysis of the amide bond in N-(4-oxoglutarate)-L-cysteinylglycine (deaminated glutathione), a metabolite repair reaction to dispose of the harmful deaminated glutathione.  Possesses amidase activity toward deaminated ophthalmate in vitro (PubMed:28373563).  Plays a role in cell growth and apoptosis: loss of expression promotes cell growth, resistance to DNA damage stress and increased incidence to NMBA-induced tumors.  Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT.  It is also a negative regulator of primary T-cells.
What are the official names of this protein?
Deaminated glutathione amidase, dGSH amidase, Nitrilase homolog 1.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.
What are the subcellular locations of this protein?
[Isoform 1]: Mitochondrion. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
Protein: LACG_STAHJ
Sequence: MKKLPEDFIFGGATAAYQAEGATQTDGKGRVAWDTYLEENYWYTAEPASDFYNKYPIDLELSEKFGVNGIRISIAWSRIFPKGYGEVNPKGVEYYHNLFKECHRRHVEPFVTLHHFDTPETLHSDGDFLNRKTIEYFVEYAKFCFEEFEEVNYWTTFNEIGPIGDGQYLVGKFPPGIKYDFAKVFQSHHNMMVAHAKAVKLFKDNGYSGEVGVVHALPTKYPYDPTNPEDVRAAELEDIIHNKFILDATYLGKYSRETMEGVQHILSVNGGKLDIPEEDYKVLEAAKDLNDFLGINYYMSDWMRGYDGESEITHNATGDKGGSKYQLKGVGQREFDVDVPRTDWDWMIYPKGLYDQIMRVVKDYPNYHKIYITENGLGYKDQFDEERKTVDDDARIDYVKKHLEVISDAIRDGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERYPKKSAYWYKELAESKEIK
What are the official names of this protein?
6-phospho-beta-galactosidase, Beta-D-phosphogalactoside galactohydrolase, PGALase, P-beta-Gal, PBG.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: SLEA_PROMU
Sequence: MGRFTFVSFGLLVVFLSLSGTGADFDCIPGWSAYDRYCYQAFSEPKNWEDAESFCEEGVKTSHLVSIESSGEGDFVAQLVAEKIKTSFQYVWIGLRIQNKEQQCRSEWSDASSVNYENLFKQSSKKCYALKKGTELRTWFNVYCGRENPFVCKYTPEC
What is the function of this protein?
Potent platelet activator that acts via GPIb (GP1BA/GP1BB) (PubMed:15175804).  After activation by the toxin, the receptor is redistributed on platelet surface thanks to cytoskeletal translocation.  The indirect activation of integrin alpha-IIb/beta-3 (ITGA2B/ITGB3) also induced by the toxin is downstream the cytoskeletal translocation of GPIb (PubMed:16102113).
What are the official names of this protein?
Snaclec mucetin subunit alpha, Trimeresurus mucrosquamatus venom activator subunit alpha, TMVA subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: MRAY_HYPNA
Sequence: MLYELLAADSGLFNLLNYITFRTGAAVVTAFLVTVLFGDMLINFLRARQGKGQPIRDLSLEMQLSKQGTPTMGGFLIWLGLIVGVALWGNLQNPYVWVTLFVTFSYAILGFLDDYAKVTKQSTDGVSAGARLIAGFGIAALACAIIMGLHGAHTPAGHAEWGPFNPLAEWIAGFAPQTSVEPADPNFSGGVAVPFVNNYFLPLGGFFILFGMIVIVGAANAVNFTDGLDGLAIVPMTFAAAAYAMIAYLTGNFVFASYLGIQFAPGAGELAVLLGALIGSGMGFLWYNAYPAKVFMGDTGSLGLGGMLGVVAVATKHEFALVVIGGLFVIEAVSVLTQIGWFKITKRLTGEGKRIFLMAPLHHHFQKKNWPETRVVVRFWILSVLFALAGLATLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TREA_XANC8
Sequence: MPHAPARSGDAMSAAAPPCCTSLLGLSLSMFVAPCALAATPLEGAVVSAPAPTPPTPDLAYPELFQAVQRGELFDDQKHFVDFLPLRDPALINADYLAQHEHAGFDLRKFVDANFEESPPVQTDAIRQDTALREHIDALWPKLVRSQTNVPAHSSLLALPHPYVVPGGRFREVYYWDSYFTMLGLVKSGETTLSRQMLDNFAYLIDTYGHIPNGNRTYYLSRSQPPLFSYMVELQAGVEGEAVYQRYLPQLQKEYAYWMQGGDDLQPGQAARHVVRLADGSVLNRYWDERDTPRPEAWLHDTRTAAEAHDRPAADVYRDLRAGAESGWDYTSRWLADGKTLSTIRTTAIVPIDLNSLLYHLERTLAQACAHTGTACSQDYAALAQQRKQAIDAHLWNAAGYYADYDWQTRTLSNQVTAAALYPLFAGLASDDHAKRTATSVRARLLRPGGLATTALKTGQQWDEPNGWAPLQWVAVDGLRRYGEDGLARTIGERFLTQVQALFAREHKLVEKYGLDADAAGGGGGEYALQDGFGWTNGVTLMLLNLYPSQGATQAPAKTKRKPEPAAP
What is the function of this protein?
Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.
What are the official names of this protein?
Periplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CHM2B_HUMAN
Sequence: MASLFKKKTVDDVIKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEACKVLAKQLVHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTMQNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEISGKMAKAPSAARSLPSASTSKATISDEEIERQLKALGVD
What is the function of this protein?
Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids.  The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes.  ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released.  The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses).  ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4.
What are the official names of this protein?
Charged multivesicular body protein 2b, CHMP2.5, Chromatin-modifying protein 2b, CHMP2b, Vacuolar protein sorting-associated protein 2-2, Vps2-2, hVps2-2.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Late endosome membrane; Peripheral membrane protein.