PharMolix/UniProtQA huggingface dataset:
Protein: LIPB_RICRS
Sequence: MIRFITIPDFADYQVILKLMEDYVNKVINDHEPEIIYLVEHSEVYTAGTNYKQEELLNYGDIPVIYTGRGGKFTFHGPGQRVIYPILNLDSPNRYKDLKLYIKMLEEWIINSLNYFGIKAYIIKDKVGIWVKVRKDEFAKIAAIGVRVRKWVTYHGVAINISTDLSKFSGIIPCGLENSLVTSLNQLGIHVEMSEFDKIIQTEFNKIFK
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5947_DICDI
Sequence: MLFKSLQLISLKSSSSNSNTTFGNVLLNGQYQSINNVTFLDHTKALADSAKNKLNAAMHNL
What are the official names of this protein?
Uncharacterized protein DDB_G0284283.
Protein: TMX2_HUMAN
Sequence: MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCDFDWREVEILMFLSAIVMMKNRRSITVEQHIGNIFMFSKVANTILFFRLDIRMGLLYITLCIVFLMTCKPPLYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLPTLILFQGGKEAMRRPQIDKKGRAVSWTFSEENVIREFNLNELYQRAKKLSKAGDNIPEEQPVASTPTTVSDGENKKDK
What is the function of this protein?
Endoplasmic reticulum and mitochondria-associated protein that probably functions as a regulator of cellular redox state and thereby regulates protein post-translational modification, protein folding and mitochondrial activity.  Indirectly regulates neuronal proliferation, migration, and organization in the developing brain.
What are the official names of this protein?
Thioredoxin-related transmembrane protein 2, Cell proliferation-inducing gene 26 protein, Thioredoxin domain-containing protein 14.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Mitochondrion membrane. Note=Localizes to endoplasmic reticulum mitochondria-associated membrane (MAMs) that connect the endoplasmic reticulum and the mitochondria.
Protein: HIS7_METJA
Sequence: MFGGNMRIFEVMRETKETNIYLKINIDGTGKYKIDTGIPFFDHLLASFAKHGCFDLIVKARGDLEIDDHHTVEDVGICLGLALNQIEKRNIFRFGWAIIPMDDARATVAIDLSGRSYCVGNYEPKREFVGDLATENINHFFESVASYGMLNIHYEVIGKNEHHKAEALFKAFGVALDLATKIDERKGVISTKGEVKL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3996_MYCPA
Sequence: MTVPKEAEGLIGSHYRAPDYFEVGREKIREFALAVKDDHPAHFDESESAAAGYPDMVAPLTFLAIAGRRVQLEIFTKFSIPINIARVIHRDQKFKFHRPILAHDRLYFDTYLDSVIESHGTVLAEIRSEVTDADGKPIVTSVVTMLGEAAHQEADAAATAAAVASISAGKLGAI
What are the official names of this protein?
UPF0336 protein MAP_3996c.
What is the protein family that this protein belongs to?
Belongs to the UPF0336 family.
Protein: ACUK_ASPNC
Sequence: MNAEPKEQDSPAPSAERTEASQEISAAGAQADKPKTEANGDGTANGASANGQKPNPKDPSRPRRKKARRACFACQRAHLTCGDERPCQRCIKRGLQDACHDGVRKKAKYLHDAPDGALMPGIGGTFYNNPMRNSLPLSRNGANAVNATGQQSAGANFYPTPQSTTYVYQENTINQGSFPSQSPVSPTFNLKATPTARTNSLSSVNPQPPSTSVSGPPGQGQNPFAGPFFDPSDPALFNFDLSSMNFENRYGALEFGMLGHMATGAGDSPSDSATQRGSMGRSGSAQYASTPITGAPGFGESPGNQQPFMFGDPLLNEWPSGQAPGQPHLPGVYPQSGQGSAIPGHLSKADAPHAFAIESGPASFNSPGATTSPQMTTGLEETPFHSAVASKSNGLAPHGQRPMITTPSLKHQNLQVGVRRRQRNPSAIYDSVKEPYAYTSRFHGLTAFIQRRFPPQKTLQIAKALASIRPSFIATTKTLNRDDLIFMEKCFQRTLWEYEDFINACGTPTIVCRRTGEIAAVGKEFSILTGWKKDVLLGKEPNLNVNTGGSSMPNSGASSRSFTPRSTVDNTPGRPQPVFLAELLDDDSVVQFYEDFARLAFGDSRGSVMTTCKLLKYKTKEDMEGAAAEDSQRWNNHLRKGGIASEAGMNQLGFKDGKVECAYCWTVKRDVFDIPMLIVMNFLPCI
What is the function of this protein?
Transcription factor which regulates nonfermentable carbon utilization.  Activator of gluconeogenetic genes (By similarity).
What are the official names of this protein?
Transcription activator of gluconeogenesis acuK.
What is the protein family that this protein belongs to?
Belongs to the ERT1/acuK family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PETS_ARATH
Sequence: MATITPSSISNAWLIPGASFTVKKSDCSIKCSFSRKAGKQILSSTQRLVLPLSTSLRLFPTHGRQFVLHPHRRATGTDVVAAVEEQDSTPVVAEDKETVASEKSDAPAPTSQSRGTARPGRKSEMPAVKNEELVPGATFTGKVRAIQPFGAFVDFGAFTDGLVHVSQLSDNFVKDVSSVVTIGQEVKVRLVEADIESKRISLTMRENDDPPKRQSGGSDKPRSGGKRDGSKGGGQRKGEGFNSKFAKGQMLDGVVKNLTRSGAFITIGEGEEGFLPTAEEADDGIGSMMMGGSSLQAGQEVKVRVLRIARGRVTLTMKEEDDGKFDETTTQGVVHTATNPFMLAFRKNEEIAAFLDKREEEAEKPPVETPVEPEAEASVTSAEVEESVCVPAEVTSEEVPSSETPKVVEEEVIATKAEDDSPEKEEQTETLAAAAEAEEVVPPIPETKSEEEIVENSIPPNSATDEVSSPEALASEEVEKEQVVAETPVDEVKTPAPVVTEASSEESGNTATAESIKGISPALVKQLREETGAGMMDCKNALSESEGDMVKAQEYLRKKGLASADKKASRATSEGRIGAYIHDSRIGVLLEVNCETDFVSRGDIFKELVDDLAMQVAACPQVEYLVTEDVSEEIVKKEKEIEMQKEDLLSKPEQIREKIVDGRIKKRLDSLALLEQPYIKDDKVIVKDLVKQRIATIGENIKVKRFVRYTLGEGLEKKSQDFAAEVAAQTAAKPKAKEEPKAEEAKEAVASPPTTVVSAALVKQLREETGAGMMDCKKALAATGGDLEKAQEFLRKKGLSSADKKSSRLASEGRIGSYIHDSRIGVLIEVNCETDFVGRSEKFKELVDDLAMQAVANPQVQYVSIEDIPEEIKQKEKEIEMQREDLLSKPENIREKIVEGRISKRLGEWALLEQPYIKDDSVLVKDLVKQTVATLGENIKVRRFVKFTLGEDN
What is the function of this protein?
Binds to psbD and psbA 5'-untranslated regions (UTRs) in vitro.
What are the official names of this protein?
Polyprotein of EF-Ts, chloroplastic, 150 kDa pro-protein, Protein EMBRYO DEFECTIVE 2726.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DSN1_MOUSE
Sequence: MTSVTRSEDQEPTMSETQDRPLQPSLKPLEALPQSSAYQEMMTQGVSEEKNHLGSNPGEGESCGADHQEGSQLRSFHLSPQEQSIRPQDRRQSWRRASMKEVNRRKSLAPFHPGITELCRSISVKLAQSQRLGALLLSSFQFSVEKLEPFLKNTKDFSLECFRAKASSLSEELKHFTDRLGNDGTLQKCFVEDSKEKAADFSLEASVAEVKEYITKFSLERQAWDRLLLQYQNEVPPEEMPRGSTETRITEVKVDPAAYLRSSQKEVLSTKPDYQRIVQDQNQVFAYVELVMDELQGSVKQLQALMDESTQYLQKVSVQLKKRSMDQLDSSPARKLLKLPLQSSPSTQ
What is the function of this protein?
Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis.
What are the official names of this protein?
Kinetochore-associated protein DSN1 homolog.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with the kinetochore.
Protein: UVSE_DEIRA
Sequence: MTSACEAVPQLGLVCLTVGPEVRFRTVTLSRYRALSPAEREAKLLDLYSSNIKTLRGAADYCAAHDIRLYRLSSSLFPMLDLAGDDTGAAVLTHLAPQLLEAGHAFTDAGVRLLMHPEQFIVLNSDRPEVRESSVRAMSAHARVMDGLGLARTPWNLLLLHGGKGGRGAELAALIPDLPDPVRLRLGLENDERAYSPAELLPICEATGTPLVFDAHHHVVHDKLPDQEDPSVREWVLRARATWQPPEWQVVHLSNGIEGPQDRRHSHLIADFPSAYADVPWIEVEAKGKEEAIAALRLMAPFKKD
What is the function of this protein?
Component in a DNA repair pathway.  Removal of UV LIGHT damaged nucleotides.  Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion.
What are the official names of this protein?
UV DNA damage endonuclease, UV-endonuclease, UVED, Endonuclease beta.
What is the protein family that this protein belongs to?
Belongs to the uve1/UvsE family.
Protein: TAM_MYCMM
Sequence: MWDPDVYLAFADHRGRPFYDLVSRIGAKRARRVVDLGCGPGNLTRYLARRWPEAIIEAWDSSPQMVAAARERGIDATTGDLRTWKPKPDTDVVISSAALHWVPEHADLMVQWATELPHGSWIAVQVPGNFETPSHAVVRALARREPYAKLMRDIPFRVGAVVGSPASYAGLLMDAGCKVDAWETTYLHQLTGKNPVLEWITGTALVPVRERLDDVSWEQFRQELIPLLDDAYPPRSDGTTMFPFRRLFIVAEVGGARRSADVS
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURI_SHEWM
Sequence: MSGPILVFDSGVGGLSILDEIRRVLPDQNYCYLFDNARLPYGELEEQELIDGCEALITATVAQLGASLVVIACNTASTLVLPVLREALTIPVVGVVPAIKPAALYSQAKHIGLLATPGTIKRSYTHSLIQEFAANCQVELYGSSELVLLAERKASGKQILQGEIAQLLSPIKVSGIDTLVLGCTHFPILKDEIQQYLGDGVLLLDSGKAVAARVSTLIKEESTLNKRQRKGHSKEMIALYTSEVGEGLKKLLAEFGFSTYSKAQTG
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: PLSY_LEGPC
Sequence: MALFIFLILVGYLMGSINSAIIVCRTFGLPDPREEGSKNPGATNVLRLGGKQYGIMVMVFDALKGILPVILAKLLSAEPVTVAFTALAAVVGHMYPVFFHFRGGKGVATTIGALLAFHFVIGVMVAATWLLVANFWRYSSLASIASISLAPFYSLILVGNLNIFPPLFMITILVLYKHRDNFNRLIDGKEPKIKFKHSVIEEIMEASPATSAEQEFPGKEVIDTNIDETEKTEQAEAVKKPKVKKATTKAKKTTSKEETTKKPKSTKPKTKTVKEKE
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS16_RHIME
Sequence: MALKIRLARGGSKKRPYYQIVVADARSPRDGRFLEKLGSWNPMLAKDDEKRIELNAERVQHWIAQGAQPTDRVMRFLDQAGLAKRPARNNPTKAQPGKKAQERAAEAKQKAEEAAAAASEAAAE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: Y325_HAEIN
Sequence: MLSNPVVISIIVLLALSLLRINVIIALVIAALTAGFIGDLGLTKTIETFTGGLGGGAEVAMNYAILGAFAIAISKSGITDLIAYKIITKMNKTPTAGNLTWFKYFIFAVLALFAISSQNLLPVHIAFIPIVVPPLLSIFNRLKIDRRAVACVLTFGLTATYILLPVGFGKIFIESILVKNINQAGATLGLQTNVAQVSLAMLLPVIGMILGLLTAIFITYRKPREYNINVEEATTKDIEAHIANIKPKQIVASLIAIVATFATQLVTSSTIIGGLIGLIIFVLCGIFKLKESNDIFQQGLRLMAMIGFVMIAASGFANVINATTGVTDLVQSLSSGVVQSKGIAALLMLVVGLLITMGIGSSFSTVPIITSIYVPLCLSFGFSPLATISIVGVAAALGDAGSPASDSTLGPTSGLNMDGKHDHIWDSVVPTFIHYNIPLLVFGWIAAMYL
What are the official names of this protein?
Uncharacterized membrane protein HI_0325.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEU1_STRCO
Sequence: MANRQQPSPMPTAKYRGYDQVDIADRTWPNQRITTAPRWLSTDLRDGNQALIDPMSPVRKRAMFDLLVKMGYKEIEVGFPASGQTDFDFVRSIIEEPGAIPDDVTISVLTQAREDLIERTVESLKGARRATVHLYNATAPVFRRVVFRGSRDDIKQIAVDGTRLVMEYAEKLLGPETEFGYQYSPEIFTDTELDFALEVCEAVMDTYQPGPGREIILNLPATVERSTPSTHADRFEWMGRNLSRREHVCLSVHPHNDRGTAVAAAELALMAGADRIEGCLFGQGERTGNVDLVTLGMNLFSQGVDPQIDFSDIDEIRRTWEYCNQMEVHPRHPYVGDLVYTSFSGSHQDAIKKGFDAMEADAAARGVTVDDIEWAVPYLPIDPKDVGRSYEAVIRVNSQSGKGGIAYVLKNDHSLDLPRRMQIEFSKLIQAKTDAEGGEITPTAIWDVFQDEYLPNPDNPWGRIQVANGQTTTDRDGVDTLTVDATVDGAETTLVGSGNGPISAFFHALQGVGIDVRLLDYQEHTMSEGASAQAASYIECAIGDKVLWGIGIDANTTRASLKAVVSAVNRATR
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
Protein: RSMH_LISMF
Sequence: MFKHETVLLHETVDMLEVKPDGIYVDATLGGAGHSEYLLNKLNEKGHLFAFDQDQTAIDNAKIKLADYSDKVTFIKANFRDMKEALNERGIEAVDGILYDLGVSSPQLDERERGFSYHQDAALDMRMDQEQELTAKIVVNEWSYQDLIRIFFQYGEEKFSKQIAREIERRREVKPIETTGELVDIIKTAIPAPARRKGGHPGKRTFQAIRIAVNDELGAVEDSLEKALTLLKPGGRISVITFHSLEDRITKQLFQEATKGPDLPPGLPVIPDEYKPDFKLATRKPIVPSEEELEQNNRARSAKLRVIEKIIK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYS_OSTED
Sequence: MSAVLVLALVLLSLTCVTDAISDACLTCICKQESYGCTQIGCRMDGRSLSCGYFQIKKSYWIDCGRLGSSWEACADDYNCAVRCVRAYMKKYIGKSGCTANCKNYARLHNGGPKGCTKPSTLTYWNAVKNQGCSINS
What is the function of this protein?
Has bacteriolytic activity (By similarity).  May play a role in digestion and in the host defense mechanisms against invading microbes (PubMed:16996284).
What are the official names of this protein?
Lysozyme, 1,4-beta-N-acetylmuramidase, Invertebrate-type lysozyme.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family. Type-I lysozyme subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ARGR_DESHY
Sequence: MKTRRQMKIQEIINNQVIHTQEELAELLRKAGFDVTQATVSRDIKEMGLIKVPTSEDDYRYAVPGTAQPLSTPDRLKRRLRETVVTVNDSENLVVLRTIPGNAQALASLIDHSNWEEVIGTVAGDDTILLVVKPAGAVPSVRERIAKLMQ
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_BACAC
Sequence: MSNGIVAKRYAVALFKIAKEKHVLEMFEEELRLVQNVYEKNGELHSFLTQPNISKEQKKTFLANVFGSVSESILNTLYILIDNKRIDILSDIANEYVVLANEERNVADATVYSTRLLSEEEKLNIAEAFAKRTGKDAIRVKNVVDEDLLGGIKVRIGNRIYDGSLQGKLARIQRELMKNR
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NIFH1_METTL
Sequence: MSFDEIAPDAKKVAIYGKGGIGKSTTTQNTAAALAYFFDKKVMIHGCDPKADSTRMILHGKPQDTVMDVLREEGEEAVTLEKVRKIGFKDILCVESGGPEPGVGCAGRGVITAVDMMRELEGYPDDLDNLFFDVLGDVVCGGFAMPLRDGLAQEIYIVTSGEMMALYAANNIAKGILKYAEQSGVRLGGIICNARNVDGEKELMDEFCDKLGTKLIHYVPRDNIVQKAEFNKMTVIEFDPECNQAKEYRTLAKNIDENDELVKPTPMTMDELEELVVKYGLIDL
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
What are the official names of this protein?
Nitrogenase iron protein 1, Nitrogenase Fe protein 1, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: ACEA_TALMA
Sequence: MASTNFDLEDQKYLEDVNAVKQWWTDSRWRYTKRPFTAEQIVAKRGTLKIEYPSNTQAKKLWKILEERFNDKTVSYTYGCLEPTMLTQMIKYLDTIYVSGWQSSSTASSTDEPSPDLADYPMNTVPNKVNQLFMAQLFHDRKQREERITTPREKRSSVQNYDYLRPIIADADTGHGGLTAVMKLTKLFVERGAAGIHIEDQAPGTKKCGHMAGKVLVPISEHINRLVAIRAQADIMGTDLLAIARTDSEAATLITSTIDYRDHAYLLGSTNPSLQPLNDLMVAAEQSGKSGEQLQAIEDSWIAQAGIKKFDDAVIDTINQGSFANKKELINRYLTAAKGKSNSEARAIAKGITGMDIYWNWDAPRTRGGFYRYQGGTQCAVNRAVAYAPFADLIWMESKLPDYKQAKEFADGVHAVWPEQKLAYNLSPSFNWKAAMSKEEQLTYIKRLGKLGYCWQFITLAGLHSTALISDQFASAYAKQGMRAYGELIQEPEMERKVDIVTHQKWSGANLIDHSLAMVTGGISSTAAMGKGVTEDQFKS
What is the function of this protein?
Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle.  Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available.  Acts also on 2-methylisocitrate.
What are the official names of this protein?
Isocitrate lyase, ICL, Isocitrase, Isocitratase, Methylisocitrate lyase, MICA, Threo-D(S)-isocitrate glyoxylate-lyase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
What are the subcellular locations of this protein?
Glyoxysome.
Protein: DLL4_XENLA
Sequence: MTGVFDSLAADMHSNHMPSSSYHSLHKSQESPTLPVSTATDSSYYTNQQQQQHCGAVSPYGQLGSYQFHGAAINGISYSTKSYDLSYTGSYSSYGPYGTSPSPPHNDQEKEDCEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGVTQTQVKIWFQNRRSKFKKMWKSGEIPSDQLPVGSESSPCSSPSASTATWDFGPHQRLQGATNGSALQSSNSASSPSPFLSNYSWYQTSNSAPHLQSNPLLQQHHLHHHPPAPISAGTIF
What is the function of this protein?
Involved in the Notch signaling pathway as Notch ligand.  Activates NOTCH1 and NOTCH4.  Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting.  Essential for retinal progenitor proliferation is required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types.  During spinal cord neurogenesis, inhibits V2a interneuron fate (By similarity).
What are the official names of this protein?
Homeobox protein DLL-4, XDLL-4.
What is the protein family that this protein belongs to?
Belongs to the distal-less homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CESA5_ORYSI
Sequence: MEASAGLVAGSHNRNELVVIRRDGEPGPKPVKHTNGQVCQICGDDVGLTPDGEPFVACNECAFPVCRDCYEYERREGTQNCPQCKTRFKRLKGCARVPGDEEEEDVDDLENEFNWRDKTDSQYVAESMLHGHMSYGRGGDLDGVPQHFQPIPNVPLLTNGEMADDIPPEQHALVPSFMGGGGKRIHPLPYADPNLPVQPRSMDPSKDLAAYGYGSVAWKERMESWKQKQERLHQMRNDGGGKDWDGDGDDADLPLMDEARQPLSRKIPISSSLVNPYRMIIIIRLVVLGFFFHYRVMHPVPDAFALWLISVICEIWFAMSWILDQFPKWFPIERETYLDRLTLRFDKEGQQSQLAPVDFFVSTVDPMKEPPLVTANTVLSILAVDYPVDKVSCYVSDDGAAMLTFEALSETSEFAKKWVPFCKRYSLEPRAPEWYFQQKIDYLKDKVAPNFVRERRAMKREYEEFKVRINALVAKAQKVPEEGWTMQDGTPWPGNNVRDHPGMIQVFLGQSGGHDVEGNELPRLVYVSREKRPGYNHHKKAGAMNALVRVSAVLTNAPYMLNLDCDHYINNSKAIKEAMCFMMDPLVGKKVCYVQFPQRFDGIDRHDRYANRNVVFFDINMKGLDGIQGPIYVGTGCVFRRQALYGYDAPKSKKPPSRTCNCWPKWCICCCCFGNRTNKKKTAKPKTEKKKRLFFKRAENQSPAYALGEIDEGAPGAENEKAGIVNQQKLEKKFGQSSVFVASTLLENGGTLKSASPASLLKEAIHVISCGYEDKTDWGKEIGWIYGSVTEDILTGFKMHCHGWRSIYCIPKRAAFKGSAPLNLSDRLHQVLRWALGSIEIFFSNHCPLWYGYGGGLKCLERFSYINSIVYPWTSIPLLAYCTLPAICLLTGKFITPELTNIASLWFMSLFICIFATGILEMRWSGVGIDDWWRNEQFWVIGGVSSHLFAVFQGLLKVIAGIDTSFTVTSKGGDDEEFSELYTFKWTTLLIPPTTLLLLNFIGVVAGVSNAINNGYESWGPLFGKLFFAFWVIVHLYPFLKGLVGRQNRTPTIVIVWSILLASIFSLLWVRIDPFLAKNDGPLLEECGLDCN
What is the function of this protein?
Probable catalytic subunit of cellulose synthase terminal complexes ('rosettes'), required for beta-1,4-glucan microfibril crystallization, a major mechanism of the cell wall formation.
What are the official names of this protein?
Probable cellulose synthase A catalytic subunit 5 [UDP-forming], OsCesA5.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. Plant cellulose synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACYP2_XENTR
Sequence: MANLAKATGKLKSVDYEVFGRVQGVCFRMYTEDEARKLGVVGWVKNTRQGTVTGQVQGPEDKVNSMKAWLSRVGSPSSRIDRIDFNDEKEITKLQYNGFSTRY
What are the official names of this protein?
Acylphosphatase-2, Acylphosphate phosphohydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: TTGA_PSEPT
Sequence: MQFKPAVTALVSAVALATLLSGCKKEEAAPAAQAPQVGVVTIQPQAFTLTSELPGRTSAYRVAEVRPQVNGIILKRLFKEGSEVKEGQQLYQIDPAVYEATLANAKANLLATRSLAERYKQLIDEQAVSKQEYDDANAKRLQAEASLKSAQIDLRYTKVLAPISGRIGRSSFTEGALVSNGQTDAMATIQQLDPIYVDVTQSTAELLKLRRDLESGQLQKAGNNAASVQLVLEDGSLFKQEGRLEFSEVAVDETTGSVTLRALFPNPDHTLLPGMFVHARLKAGVNANAILAPQQGVTRDLKGAPTALVVNQENKVELRQLKASRTLGSDWLIEEGLNPGDRLITEGLQYVRPGVEVKVSDATNVKKPAGPDQANAAKADAKAE
What is the function of this protein?
The periplasmic linker protein component of a constitutive organic solvent efflux system.  Involved in export of toluene, styrene, m-xylene, propylbenzene and ethylbenzene.  Also exports AMP and the antibiotics carbenicillin, nalidixic acid, chloramphenicol and tetracycline.
What are the official names of this protein?
Toluene efflux pump periplasmic linker protein TtgA.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor.
Protein: ATPE_SULDN
Sequence: MSKLKLEILTPNGVIYNGEALSVTLPGEEGEFGVLAEHSSLITLLEAGVIDIEKEDKSVESVLINWGVVEVDEKKVIVLVEGAVAIRGDSESAVAKALNDAKELIESIKDNNPAIATVTARLESAAQNLL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ATP23_ASPFU
Sequence: MSDSQPCSTPSTRGKSDSGYIPGDDTWTQWRNIFAILTGQMTDEGKEQFRIARDIRNEAADCKRCEDQRDYLLQYSPIIRFLSDNIRQLRGDLSSHNIYCRRCTSRKAGGFDPEYGILLCANEMKDQGHLEDTMAHEMVHAYDHLRFKVDWTDNLRHAACTEIRASSLSGECRWAREFFRRGQWKFTQQHQECVRRRAILSVRARPGCKDEAHAEKVVNEVWDSCFRDTRPFDEIYR
What is the function of this protein?
Has a dual role in the assembly of mitochondrial ATPase.  Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side.  Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring (By similarity).
What are the official names of this protein?
Mitochondrial inner membrane protease atp23.
What is the protein family that this protein belongs to?
Belongs to the peptidase M76 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Associates loosely with the inner membrane.
Protein: MRAY_BORHD
Sequence: MFDLLGLRLLHYITFRTAYATIFAFLLALIFGPFIILRLKKLKLDQILREDGPKRHLSEKMGIPTMGGILIFFCVLVSLFFWINLWNVYFLIVLFVMISFACLGFMDDLLKIKRKNADGLNPRFKIYGQILFSCISVTMLYYFGGEHISIIYFPFFKSLKLDLGVLYIPFGMFILISASNSFNLTDGLDGLAIGLSIVVTGALVIIAYLTSRVDFATYLNIPNIKGSEELVIFLGALLGGSFGFLWFNAYPAKIMMGDTGSLSIGAVLGMTALILKSEILFAILAGVFVLETLSVIIQVAVYKKTKKRVFKMAPLHHHFEELGWSETQVVIRFWIIGLIFAIIALSTLKIR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GCSH_SYNP2
Sequence: MELEYPDDLRYLDSHEYIRLDGEIATIGLSAHAIDELGDIVFLELPEEGDAIVVGETFGSIESVKAVEDLYAPISGTVIDRNEALIQSPEMVSEDPYEEGWFIKVRVDNLDDEMLAETMTAEEYRLQVAGEE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.