PharMolix/UniProtQA huggingface dataset:
Protein: UBIC_ECO24
Sequence: MSHPALTQLRALRYFKEIPALDPQLLDWLLLEDSMTKRFEQQGKTVSVTMIREGFVEQNEIPEELPLLPKESRYWLREILLCADGEPWLAGRTVVPVSTLSGPELALQKLGKTPLGRYLFTSSTLTRDFIEIGRDAGLWGRRSRLRLSGKPLLLTELFLPASPLY
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_HELPY
Sequence: MQKSLITTPIYYVNDIPHIGHAYTTLIADTLKKYYTLQGEEVFFLTGTDEHGQKIEQSARLRNQSPKAYADSISTIFKDQWDFFNLDYDGFIRTTDSEHQKCVQNAFEIMFEKGDIYKGAYSGYYCVSCESYCAISKADNTNDKVLCPDCLRETTLLEEESYFFRLSAYEKPLLDFYAKNPEAILPVYRKNEVTSFIEQGLLDLSITRTSFEWGIPLPKKMNDPKHVVYVWLDALLNYASALGYLNDLDNKMAHFECARHIVGKDILRFHAIYWPAFLMSLNLPLFKQLCVHGWWTIEGVKMSKSLGNVLDAQKIAMEYGIEELRYFLLREVPFGQDGDFSKKALIERINANLNNDLGNLLNRLLGMAKKYFNHSLKSTKITAYYSKELEKVHQILDNANSFVPKMQLHKALEELFNVYDFLNKLIAKEEPWVLHKNNESEKLEALLSLIANALLQSSFLLYAFMPKSAVKLANAFNTEITPDNYERFFKAKKLQDMILQDTEPLFSKMEKIEKTEKAGEASPEKNEKEKKDAKEKAPLKQENYIGIEDFKKVEIKVGLIKEAQRIEKSNKLLRLKVDLGEGRLRQIISGIALDYEPESLVGQMVCVVANLKPAKLMGEMSEGMILAVRDSDNLALISPTREKIAGSLIS
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_FUSNN
Sequence: MSRRRAAVKRDVLPDSRYSDKVVTKVINSIMLDGKKSIAEGIFYSAMDLIKEKTGQEGYDIFKQALENIKPQIEVRSRRIGGATYQVPVEVKADRQQTLAIRWLTTYTRARKEYGMIEKLAAELIAAANNEGATIKKKEDTYKMAEANRAFAHYRV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: HEM2_CHLTE
Sequence: MSQLDLLNIVHRPRRLRRTAALRNLVQENTLTVNDLVFPLFVMPGTNAVEEVPSMPGSFRFTIDRAVEECKELYDLGIQAIDLFGIPEKKTEDGSEAYNDNGILQQAIRAIKKAVPELCIMTDVALDPFTPFGHDGLVRDGIILNDETVEVLQKMAVSHAEAGADFVSPSDMMDGRIGAIREALDESDHSDVGILSYAAKYASSFYGPFRDALHSAPQFGDKSTYQMNPANTDEAMKEVELDIIEGADIVMVKPGLAYLDIVWRTKERFDVPVAIYHVSGEYAMVKAAAANGWIDEERVMMESLLCMKRAGADIIFTYYAKEAAKKLR
What is the function of this protein?
Catalyzes an early step in the biosynthesis of tetrapyrroles.  Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).
What are the official names of this protein?
Delta-aminolevulinic acid dehydratase, ALAD, ALADH, Porphobilinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the ALAD family.
Protein: COG2_DICDI
Sequence: MAMNLKNSSSGGNLTSSPSYNSFSSLNLSGNSFNNGSGSGSGSGSGSNEYIPLCFSKDVFTSNTFEVDQFISDCRKRVNLESVQKDLREYSKHLDSELIELINKEYQSFFSLSTSLVGFDTILNEFSISQSSIKSEIKSFNNEIVKVRGLVEDKLNEKKSIEQKKKLLQLYISISETLNNMNHLFDQLYQLTHPNDFKKINNNNNNHTNNETNINDGDVLELLIDRISNSFYQIQNQMSSLTNDELKFNIFQSLSLKIMDLSNKIEEKVEPIFKESLKRFINVNNNNKEIVDDNNEKQNKYDERILLVCLKTFQTIDKLNVPYKLFKTLIVKPRLAQIVSLRNLEINKSTTDGLSQIYNSIIEFLKNQCSSFFDISNLINNNLKEKQSNNNNNNNNNNNNNNNNNNNNQINNNSNNNNNNINNNNINNNYNNNIILYNNYNFISQSVLPEIDESLGFFKQIFATGIPDLFYKNYYLTFNFIQSIEVNFLTNKELLTQFRQSSSYSSLWKKWNFAVYFQLCFTNIAQHFEFNYLRIPLFDQLTLPTNNITNNNNNNNENNNEFYLKSTDGLRLSMDKCWSNSNFIFDLSSKFFKLFLQLIARYDTFISDTLIPLELELQQQLQQQQLQQQQQQQQQQQNIGDSVIKITPKSPPSLSNQSPISSSTTLNNKQSSPENFIYIISDIYKIKSKISTNYKELIIKTIGNHQNQHEILNLINDGILESCKTLEQLIPRISIIIENHLISKCLEPIEIISTLRSTYRMTNKPVPTKPSIYVSNLISPLEILINNKASSLHFIPPEIKLNWAISVLTPVTESFKNAATNLIQSVTQSNDIINKMVKKSKPTTTTSGGDMSDMDKISLQLYLDVDKFGLYIQKFGINLLTFEPFLGLKSIVEPFKKLILNQNK
What is the function of this protein?
Required for normal Golgi function.
What are the official names of this protein?
Conserved oligomeric Golgi complex subunit 2, COG complex subunit 2, Component of oligomeric Golgi complex 2.
What is the protein family that this protein belongs to?
Belongs to the COG2 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein.
Protein: TRMA_CAMJD
Sequence: MSLENFGNFLTLDEKHSFIKKYFKEFYTKDFKLFTSKDKHYRTRAELSFYHENDTLFYAMFDPKSKKKYIIEYLDFADEKICAFMPKLLEYLRQDDKLKEKLFGVEFLTTKQELSLTLLYHKNIEDIKSNLENLSNNLHINLIARSKGKKLIFKTENLRQTLNIQGREIFYEFNNDCFIQPNTTINEKMITWVCEILSIQKRMDLLELYCGYGNFTLALAQFFFKVLATEISKSSINFALKNCKLNNTTNIHFARLSSEELSLAIKKEREFFRLKDIRLDDFNFSHVLVDPPRAGLDKSVIDLIKKYENIIYISCNPITLKENLKELSLTHRVENFALFDQFVNTPHLECGVFLSKV
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: ARGE_PHOLL
Sequence: MNIKLPPFIELFRQLIATPSISATDISIDQSNESLINLLASWLKEIGFEIEIQPVPETLGKYNLLATLGRGPGGLLLCGHTDTVPFDEGLWTKDPFTLTERDNKLYGLGTADMKGFFAFIIDALRDIDVSKITRPLYILATADEETTMAGARYFAASTTIRPDFAIIGEPTSLHPICAHKGHLSNAIRIVGQSGHSSDPDRGINAIDLMHESIGHLIELRNTLKEHYNNPAFTIPYPTMNFGYIHGGDAVNRICAHCELHMDIRPLPGLTLQDLNGLLNEALEPMKQRWPGRLTIDELHSPIPGYECPTDHKMVDVIEKLLGRKAETVNYCTEAPFIQKVCPTLVLGPGSIEQAHQPDEFIDMSFIGPTRKIISQLIDHFCLSNN
What is the function of this protein?
Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids.  Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
What are the official names of this protein?
Acetylornithine deacetylase, AO, Acetylornithinase, N-acetylornithinase, NAO.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. ArgE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_RICBR
Sequence: MTNLDRHLSKFAYREEFAGNTEVLATAAYKEDCADASTGLTPKLPLEVEFGKMSKRPDWIKVKAPNSSEYYNTKDLIKNLKLNTVCEEAACPNIGECWSKKHATVMILGSVCTRACRFCNVKTGRPDLLDPHEPQRLAEAVQKLGLKHVVITSVDRDDLEDGGATHFAECISEIRKSSPNTTIEILTPDFLRKDGAAEIIANAKPDVFNHNVETVPSLYNTIRPGARYYNSLSLLHNIKKLSPEVFTKSGMMVGLGEEISEVVQVMDDLREAKVDFLTIGQYLQPTKNHAEVAKYVTPEEFKYLERVARTKGFLMVSASPLTRSSYHADEDFEKLKENYRHRHCEERRSIDVAIS
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAL2_ORYSJ
Sequence: MECENGRVSANGMSGLCVAAPRADPLNWGKATEEMTGSHLDEVKRMVAEYRQPLVKIEGASLRIAQVAAVAAAGEARVELDESARERVKASSDWVMNSMMNGTDSYGVTTGFGATSHRRTKEGGALQRELIRFLNAGAFGTGTDGHVLPAEATRAAMLVRINTLLQGYSGIRFEILEAIAKLLNANVTPCLPLRGTITASGDLVPLSYIAGLVTGRENAVAVAPDGSKVNAAEAFKIAGIQGGFFELQPKEGLAMVNGTAVGSGLASTVLFEANILAILAEVLSAVFCEVMNGKPEYTDHLTHKLKHHPGQIEAAAIMEHILEGSSYMKHAKKLGELDPLMKPKQDRYALRTSPQWLGPQIEVIRAATKSIEREINSVNDNPLIDVSRGKALHGGNFQGTPIGVSMDNTRLAIAAIGKLMFAQFSELVNDFYNNGLPSNLSGGRNPSLDYGFKGAEIAMASYCSELQFLGNPVTNHVQSAEQHNQDVNSLGLISSRKTDEAIDILKLMSSTFLIALCQAVDLRHIEENVKSAVKSCVMTVAKKTLSTNSTGDLHVARFCEKDLLKEIDREAVFAYADDPCSHNYPLMKKLRNVLVERALANGAAEFNADTSVFAKVAQFEEELRATLPGAIEAARAAVENGTAAIPSRITECRSYPLYRFVREELGTKYLTGEKTRSPGEELNKVLVAINEGKHIDPLLECLKEWNGEPLPIC
What is the function of this protein?
This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton.
What are the official names of this protein?
Phenylalanine ammonia-lyase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF2_CAMHC
Sequence: MDNYEYSELLKELKNKISNVEAIIKPKILMTRLAEIEKTEQDPALWVDAKKAAQIGREKTKISNILAKFKKAQNELNDAKEFYELAVSENDGETINELFRESAKLSENIANLELSMMLSGENDDKNAIINIHPGAGGTEGEDWAGMLYRMYVRFCERVGYKIEILDFQEGDEAGIKDVNFIVKGENAYGYLKVESGIHRLVRISPFDSAGRRHTSFASVVVSPELDDDIQINIDEKDLRIDYYRSSGAGGQHVNKTESAVRITHIPTNIVVQCQNDRDQHKNKASAMKVLKSRLYELEKLKKQEESNKTPKSDIAWGYQIRNYVLFPYQQVKDLRSNIAYSQAEAILDGDIKKILEDVLINNQS
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHSE_PYRCJ
Sequence: MRAPSTSANLGAGFDVVAVAHDAYFAEAYVAVEQGCGVAVKFKGYDPGENNTVSLAFRHLFNMLGICRQVEVVVDNRIPLARGLGSSGASAVAALAAFIREAGLKAEPKLVVEAAGLGEVAAAGSPHFDNVAGAALGGAVVVVSTSPLEVVKFSPKLLFVVGVPDVPPIPEKTRLMRSVLPREVPFKTYVAQLARVSALVAGFATSNPRLVALGMSDDVVEPARAPYVHGYARARRYALEAGALGFAISGAGPSVVALVDDKHSDAVRAALARAYAEEGLRAEVKVAQVAEGALGV
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_MYCPU
Sequence: MAKLDFDRSKEHVNIGTIGHVDHGKTTLTAAIATVLSKKGLAEAKDYASIDAAPEEKARGITINTAHIEYETEKRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSATDGPMPQTREHILLSKQVGVPKMVVFLNKVDMLEGEDEMIELVELEIRSLLSEYGFDGDKTPIIKGSALKALEGNPQYEKNIEELMDAVDNYIETPVKELDKPFLLAVEDVFTITGRGTVATGKVERGQLNINSEVEIVGFTEKPKKTTVTGIEMFRKNLKEAQAGDNAGLLLRGVDRNDVERGQVLAKPGSIVPHSKFEAAIYALKKEEGGRHTPFFSNYKPQFYFRTTDVTGGVVFPAGREMVMPGDNVDLVVELISPIAVEEGTKFSIREGGRTVGAGSVTKILK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSPAL_TRIAB
Sequence: VVGGDECNINE
What is the function of this protein?
Thrombin-like snake venom serine protease.  Releases both fibrinopeptides A and B after 90 min incubation, but only fibrinopeptides A after 10 min incubation.  Clots fibrinogen with different clotting time depending on the species: bovine > dog = human > goat.  Fails to clot both rabbit and cat fibrinogens.
What are the official names of this protein?
Thrombin-like enzyme albolabrase, SVTLE albolabrase, Fibrinogen-clotting enzyme, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AGAL_RHIME
Sequence: MASFKIAIIGAGSIGFTKKLFTDILSVPELRDVEFALTDLSEHNLAMIKSILDRIVEANELPTRVTATTDRRKALEGARYIISCVRVGGLEAYADDIRIPLKYGVDQCVGDTICAGGILYGQRNIPVILDFCKDIREVAEPGAKFLNYANPMAMNTWAAIEYGKVDTVGLCHGVQHGAEQIAEILGARDGELDYICSGINHQTWFVDVRLNGRKVGKDELVAAFEAHPVFSKQEKLRIDVLKRFGVYSTESNGHLSEYLPWYRKRPDEISRWIDMSDWIHGETGGYLRYSTETRNWFETEYPRFLEEAGRPLETIRRSNEHASRILEALETGRVYRGHFNVKNNGVITNLPADAIIESPGFVDRFGINMVAGITLPEACAATCISSVNVQRMSVHAAITGDIDLLKLAVLHDPLVGAICTPEEVWQMVDEMVVAQAKWLPQYAHAIDAAKERLARATVATREWKGAARREVRSIEEIRAEKEAAKLRAAG
What are the official names of this protein?
Alpha-galactosidase, Melibiase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 4 family.
Protein: Y381_RICFE
Sequence: MLYQNITNNSCINQALELYHKYCYDKTTYPDQIHTITKALQLDSSSFTAVLLHENIQHLNLEDYNHFNNNIIYLVDVINKLSTIHYKPYAEQYIHFHELLLTINPKLQETAILTSLVPLLHKVSIFNLEYNNTNAQHISEIITNCYIPYLLSYTAHNDLAYLLQDLCFKIQYPEERNRILHYMYWLYPDIDNIIHNIEQQFGNIFRKLNIKASLSYRIKSPYSIWIKTLVKDIHITALNDILAFRAIVPNKKACYDVSKLIHLHYNTITSQFVDYIRYPKNNGYQSIHLVISGGNKGNIELQIRSTTMHRQTQYGSAHHTYKVNKYYVSRTNNNVSVVLFNITLSYSNRILSVYVSIVTITSTINNNLYTDYNTIPSFTQYTQHSTNFVDNDITTCTLSRTTTPEYITYYNNNLSLLIKDTNTIPYNFFLNINLNLSNTVEYKLVPLAVVQIPASNLLFEHNSVFINITYKPILAECAFPATITYTKRHEDSNIRSIFKLFEHNSVFINITYKPILAECAFPATITYTKRHEDSNIRSIFKPPSPTYNTLLATINDKVVLEQYGQKEFLSTTINTNITQMLPIITLLVDPSELNKRINDISDSNKDQLLRLGLQLGCVESVPLLITHGANPNATNCHGVISLHCAAKNGNLDLAKLLAKNGADVNAKTDNGETVLHYAVKSGNLHLVKWLIENQANIHAKTDNGETVLHYAVSFNNSDLVYLLIAYGADVNAKTDNGLTALHYAVYDGNLDLVSLLISHGADVNAKTNSGETILYSAVDYGSPDLVYLLIAYGADVNAKTDNGETVLHYAVESGNLDLVSLLIHNGANVNNAKTILHFAAKSGNLNLVNWLIKNKADIHAKTNSGETILHFAAESGNLNLVNWLIKNKADIHAKTNSGETILHFAAKSGNLNLVNWLIKNKADIHAKTNSGETILHFAAKSGNLNLVNWLIKNKADIHAKTNSGETILHFAAESGNLNLVSLLIHNGTDINTKTDDGLTALHYAVESGNLNLVSLLIHKGIDVNAKTNSGETILHFAVDLGSLDLVSLLMVRGADVNAKTDDGLTALHYAVESDNLALVSLLMVYGADVNAKNNSGETPLHYAVIFNSLDLVSLLIHNGADINTKNNSGETVLNSIMEFNNCNILKSFILGGADINLETMLPDDQTDSIINLCGDLRIS
What are the official names of this protein?
Putative ankyrin repeat protein RF_0381.
Protein: TOTZ_DROYA
Sequence: MYFAIRLSFVLAVLFCLTGNGNARMLGADFNRLQQLQRRSHQSNDANTQLKIAYEVIGIYDKYKGQKGSDLLREAQLNSEVNDFKRKNVVVDGVPAQGGGIKDAVKKIADEVPDDVKKNAKDIAVKIAKSVTKSIFKYFLN
What is the function of this protein?
A humoral factor that may play a role in stress tolerance.
What are the official names of this protein?
Protein Turandot Z.
What is the protein family that this protein belongs to?
Belongs to the Turandot family.
What are the subcellular locations of this protein?
Secreted.
Protein: YIDD_CORGL
Sequence: MCAPTSDDPFDIPEPKSIPAKTAASAVRFYQKYLSGLKMGSTCRFDPVCSTYALKAVSVHGAFKGTILSAARLSKCGPWHPGGFDPVPNHGFWSTETVT
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RLMKL_PSEE4
Sequence: MSDRFELYLTCPKGLEGLLAEEANQLGLTEVREHTSAIRGSADMETAYRLCLWSRLANRVLLVLKRFSMKNADDLYDGVHAVDWAEHLEADGTLAVEFSGHGSGIDNTHFGALKVKDAIVDKLRSREGLRPSVDKLDPDLRVHLRLDRGEAILSLDLSGHSLHQRGYRLQQGAAPLKENLAAAVLIRAGWPRIAAEGGALADPMCGVGTFLVEAAMIAADIAPNLKRERWGFSAWLGHVPALWRKLHDEAQARAQAGLAKPPLWIRGYEADPRLIQPGRNNVERAGLGDWVKIYQGEVASFEPRPDQNQKGLVISNPPYGERLGDEASLLYLYQNLGERLRQACMGWEAAVFTGAPELGKRMGIRSHKQYAFWNGALPCKLLLFKVQPDQFVTGERRQAAVEEGEPRRQAPVASEPARLSEGAQMFANRLQKNFKQLGKWARREQVDCYRVYDADMPEYALAVDLYQDWVHVQEYAAPRSVDPDKAQVRLLDALAAIPQALGIDPQRVVLKRRERQSGTRQYERQATEGRFQEVTEGGVKLLVNLTDYLDTGLFLDHRPMRMRIQREAVGKRFLNLFCYTATATVHAAKGGARSTTSVDLSKTYLDWARRNLSLNGFSERNRLEQSDVMAWLQNNQESFDLIFIDPPTFSNSKRMEGVFDVQRDHVELLDLAMARLAPGGVLYFSNNFRKFQLDEHLSTRYAVEEISAQTLDPDFARNNRIHRAWQLRLR
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CONB1_LUPAL
Sequence: MGKMRVRFPTLVLVLGIVFLMAVSIGIAYGEKDVLKSHERPEEREQEEWQPRRQRPQSRREEREQEQEQGSPSYPRRQSGYERRQYHERSEQREEREQEQQQGSPSYSRRQRNPYHFNSQRFQTLYKNRNGKIRVLERFDQRTNRLENLQNYRIVEFQSKPNTLILPKHSDADYVLVVLNGRATITIVNPDRRQAYNLEYGDALRIPAGSTSYILNPDDNQKLRVVKLAIPINNPGYFYDFYPSSTKDQQSYFSGFSRNTLEATFNTRYEEIQRILLGNEDEQEYEEQRRGQEQSHQDEGVIVRVSREQIQELTKYAQSSSGKDKPSQSGPFNLRSNEPIYSNKYGNFYEITPDRNPQVQDLDISLTFTEINEGALLLPHYNSKAIFIVVVGEGNGKYELVGIRDQQRQQDEQEEEPEEVRRYSARLSEGDIFVIPAGYPISVNASSNLRLLGFGINAYENQRNFLAGSEDNVIRQLDREVKELTFPGSAEDIERLIKNQQQSYFANALPQQQQQSEKEGRRGRRGPISSI
What is the function of this protein?
Has a lectin-like activity.
What are the official names of this protein?
Conglutin beta 1, Protein Lup-1.
What is the protein family that this protein belongs to?
Belongs to the 7S seed storage protein family.
Protein: ARLY_RHIEC
Sequence: MAENNTDTKSSNQMWGGRFASGPDAIMEEINASIGFDKKLFAQDIRGSIAHATMLAHQGIISSDDKDKIVHGLNTILSEIESGNFEFSRQLEDIHMNVEARLATLIGPAAGRLHTARSRNDQVALDFRLWVKEELQKTEQMLTGLIAAFLDRAEEHAESVMPGFTHLQTAQPVTFGHHCMAYVEMFGRDRSRVRHAIEHLDESPIGAAALAGTGYPIDRHMTAKALGFREPTRNSIDTVSDRDFAIEFLAIAAIAGMHLSRLAEEIVIWSTPQFGFVRLSDAFSTGSSIMPQKKNPDAAELVRAKTGRINGSLIALLTIMKGLPLAYSKDMQEDKEQVFDAAESLELAIAAMTGMVRDMTVNTARMKAAAGSGFSTATDLADWLVREAGLPFRDAHHVTGRAVALAESKGCDLAELPLSDLQAIHSAITDKVYDVLTVEASVASRKSFGGTAPSEVRKQIAFWRARN
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C11B3_RAT
Sequence: MALRVTADVWLARPWQCLHRTRALGTTATLAPKTLKPFEAIPQYSRNKWLKMIQILREQGQENLHLEMHQAFQELGPIFRHSAGGAQIVSVMLPEDAEKLHQVESILPRRMHLEPWVAHRELRGLRRGVFLLNGAEWRFNRLKLNPNVLSPKAVQNFVPMVDEVARDFLEALKKKVRQNARGSLTMDVQQSLFNYTIEASNFALFGERLGLLGHDLNPGSLKFIHALHSMFKSTTQLLFLPRSLTRWTSTQVWKEHFDAWDVISEYANRCIWKVHQELRLGSSQTYSGIVAALITQGALPLDAIKANSMKLTAGSVDTTAIPLVMTLFELARNPDVQQALRQETLAAEASIAANPQKAMSDLPLLRAALKETLRLYPVGGFLERILNSDLVLQNYHVPAGTLVLLYLYSMGRNPAVFPRPERYMPQRWLERKRSFQHLAFGFGVRQCLGRRLAEVEMLLLLHHMLKTFQVETLRQEDVQMAYRFVLMPSSSPVLTFRPIS
What is the function of this protein?
Converts 11-deoxycorticosterone into corticosterone, 18-hydroxycorticosterone, and aldosterone.  Can also catalyze the conversion of 11-deoxycortisol to cortisol, 18-hydroxycortisol and cortisone.
What are the official names of this protein?
Cytochrome P450 11B3, mitochondrial, Aldosterone synthase, CYPXIB3, Cytochrome P450-Aldo-2, Steroid 11-beta-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Mitochondrion membrane.
Protein: HIS4_CAMJ8
Sequence: MTQIIPALDLIDGEVVRLVKGDYEQKKVYKYNPLEKFKEYEKAGAKELHLVDLTGAKDPSKRQLALIEKLAKEVNVNLQVGGGIRSKEEVKALLDCGVKRVVIGSMAIKDATLCLEILKEFGSEAIVLALDTILKEDYVVAVNAWQEASDKKLMEVLDFYSNKGLKHILCTDISKDGTMQGVNVRLYKLIHEIFPNICIQASGGVASLKDLENLKGICSGVIVGKALLDGVFSVEEGIRCLQNA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GBRD_MOUSE
Sequence: MDVLGWLLLPLLLLCTQPHHGARAMNDIGDYVGSNLEISWLPNLDGLMEGYARNFRPGIGGAPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYNHTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVACDMDLAKYPLDEQECMLDLESYGYSSEDIVYYWSENQEQIHGLDRLQLAQFTITSYRFTTELMNFKSAGQFPRLSLHFQLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLTMTTLMVSARSSLPRASAIKALDVYFWICYVFVFAALVEYAFAHFNADYRKKRKAKVKVTKPRAEMDVRNAIVLFSLSAAGVSQELAISRRQGRVPGNLMGSYRSVEVEAKKEGGSRPGGPGGIRSRLKPIDADTIDIYARAVFPAAFAAVNIIYWAAYTM
What is the function of this protein?
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit delta, GABA(A) receptor subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRD sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: IXTPA_CORJK
Sequence: MRVLVASRNKKKLAELNRMLEAANVTGIELVGLGDLPEYPETPETGATFVDNARIKTNDGVRHTGLPTIADDSGLAVDALNGMPGVLSARWSGGHGDDKANNDLLLAQMGDVPDERRGAHFVSSCVLQLPAQVAAERGMETEYAVEGRWYGRVLRAEQGEGGFGYDPLFAPDELPEGQEEQLAGKSAGELTAEQKDAVSHRGKALRQLVEILAQLAD
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: ATPD_BACMK
Sequence: MSNGIVAKRYAVALFKIAKEKHVLEMFEEELRLVQNVFTKNGELHSFLTQPNISKEQKKTFLANVFASVSESILNTLYILIDNKRIDILPEIANEYVVLANEERNVADATVYSIRLLSEEEKLNIAEAFAKKTGKDAIRVKNVVDEDLLGGIKVRIGNRIYDGSLQGKLARIQRELMKNR
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YIDD_STRZP
Sequence: MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFKGVLMGLSRILRCHPWSKTGKDPVPDRFSLKRNQEGE
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KR271_HUMAN
Sequence: MPHSHCHSLRSFHNAPPLSAITHGTNPITFEDRLCLPSSFHSRTCFLDNFQETCNETTSCQMTNCEQDLFTDDSCVQSNCFPGVVQTTYSNSRPCERTACQSESSSAGLACVSQPCQSESTQQMGFVAQSCQPASLKGNSCPPKTSKSKNFETLERASSQCQCQSQNPESSSCRPLVNVAPEPQLLESSPGVEPTCCVTGGSQLPSK
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 27-1.
What is the protein family that this protein belongs to?
Belongs to the PMG family.