PharMolix/UniProtQA huggingface dataset:
Protein: GPDA_HERAR
Sequence: MNITILGAGAWGTALAMSLADRHSVMLWGRDAAVMQEAEQRRENTVYLPGFRLPDSLSLSSDFSAAIAHVGTDGLLLVATSLAGLRPLAMQLQPYAIPNIVWLCKGFEADTHLLPHQIVREVLGNDIPAGALSGPSFAQEVAQGLPCALAIASDNAALRELVVSAVHGPSMRIYSTDDVIGVEVGGAVKNILAIATGIIDGLKLGMNARAALITRGLVEITRFGVALGGRTETFMGLAGMGDLILTCTGDLSRNRKVGLGLAQGKKLEQIVTELGHVAEGVRCAQAVRSLAAERGIDMPITNAVAAVLFDGDLPREMVGRLLARDARNEMA
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPLA_SALTI
Sequence: MTTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTISTHIVLAALNSLGVMADASGRNDLVVKTPDGDRKVSGSAYRETKDRGFHHGTLLLNADLSRLANYLNPDKKKLAAKGITSVRSRVANLTELLPGITHEQVCQAVTEAFFAHYGERIDAEVISPDKTPDLPNFTETFARQSSWEWNFGQAPAFSHLLDERFTWGGVELHFDVEKGVITRAQAFTDSLNPAPLEALAGRLQGCQYRADKLQETCEALIATFPEQESELRELANWVAGAVR
What is the function of this protein?
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
What are the official names of this protein?
Lipoate-protein ligase A, Lipoate--protein ligase.
What is the protein family that this protein belongs to?
Belongs to the LplA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZAPB_PSYIN
Sequence: MTLDLLEQLESKIQNTVDTIALLQMEVEELKEDKQVLTEKGEQLQAENIRLTEEHQKWQSRLSALVGKIEETES
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid- cell, in a FtsZ-like pattern.
Protein: FTSH3_ORYSJ
Sequence: MSLSSLSRALARSARSSRQRQGSLLGGHGGLRASSPPLPCGELGFLRSYVTSVIGNRAAVASGAGKGGDWRFLLASRQFRRLFSDKSKKNHGKHSEEENKGKGDESDKSDSKKQSSSGDQWNFEESIKQFKDMIAPLFLFGLLLLSASASSSEQEISFQEFKNKLLEPGLVDHIVVSNKSIAKVYVRSSPSIDRIQDSDIHITTSHLPGIESPSSYKYYFNIGSVDSFEEKLQEAQKALEIDPHYYVPITYTTEAKWFEEVMKYVPTVLIIGLIYLLGKRIQNGFTVGGGPGKGGRSIFSIGKVQVTKLDKNSKNKVFFKDVAGCDEAKQEIMEFVHFLKNPKKYEELGAKIPKGALLVGPPGTGKTLLAKATAGESGVPFLSISGSDFMEMFVGVGPSRVRNLFQEARQCSPSIVFIDEIDAIGRARGRGGFSGGHDERESTLNQLLVEMDGFGTTSGVVVLAGTNRPDILDKALLRPGRFDRQISIDKPDIKGRDQIFRIYLKKLKLDKEPSFYSQRLAALTPGFAGADIANVCNEAALIAARSEGTLITMQHFESAIDRVIGGLEKKNKVISKLERRTVAYHESGHAVAGWFLEHAEPLLKVTIVPRGTAALGFAQYVPNDNLLMTKEQLFDMTCMTLGGRAAEEVLIGKISTGAQNDLEKVTKMTYAQVAVYGFSEKVGLLSFPQREDGFEMSKPYSSQTASIIDTEVREWVAKAYEKTVELIKQHKDQVAQIAELLLEKEVLHQDDLVQVLGERPFKTLEPTNYDRFKQGFQDEDSNRNAELSNADGASSLGEAVAS
What is the function of this protein?
Probable ATP-dependent zinc metallopeptidase.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FTSH 3, mitochondrial, OsFTSH3.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: PFDA_METS5
Sequence: MAESNNRMVVSLEDLLAQADALRKEIDALQKLRDEIAESLNAARSAKEAINLIKGQGKDLLLSADRRGFVLLKVTEIPSSKVLVNLGLGYYAEIEPDQASKILDEREEQLNKSLQDITARLNNAVNAYTQIAEILNRAQQQQGE
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit alpha, GimC subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the prefoldin alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NODS_RHITR
Sequence: MKLRFAGTILREMLPDRWHMTAFAPTSNDRSIKVDGLKTHDNYQLLNRELAADDPWRLDGNPFERKRHAQMLLLSLAQGPIANALEVGCAAGAFTEKLAPHCQRLTVIDVVPEAIDRTRRRMNKPAHISWVVSDVQQFSSEELFDLIVVAEVLYYLGDIAEMRMAVGNLLRMLAPGGHLVFGSARDANCQRWGHVTGAETVIAILTEMLVEVERLELQGDSDNEDCLLVRFRNPVSSS
What is the function of this protein?
SAM-utilizing methyltransferase involved in nod factor synthesis.
What are the official names of this protein?
Nodulation protein S.
What is the protein family that this protein belongs to?
Belongs to the NodS family.
Protein: COBT_PROA2
Sequence: MIEQFQQVLASVKSVDMSLTKEVQAHLDDLTKPRGSLGRLEEIAMKYVLATGSLRPELRKKKVFCFAADHGVAVEGVSAFPAEVTPQMVYNMLAGGAAINVLSRHAGADLDVVDMGVHHDFVEHPSLRICKVRHGSSNMAEGPAMTMDETLQAIMTGVSLAHEARKEGYDLLATGEMGIANTTPATALYASMLDLPVEMITGRGTGIDDAVLQHKISVIKRALDVNSASLSTPLEQLAALGGFEIAGICGLILGAASVGMPVVVDGFISSAGAVAALKLSCRVSDYLFFSHLSNEQGHKAIMNRLGARPILDLDLRLGEGTGAALAMQVVEASVKLYNEMATFSSASVSGKSV
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: TUSD_ECOUT
Sequence: MRFAIVVTGPAYGTQQASSAFQFAQALIAEGHELSSVFFYREGVYNANQLTSPASDEFDLVRSWQQLNMQHGVALNICVAAALRRGVVDETEAGRLGLASSNLQTGFTLSGLGALAEASLTCDRVVQF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Accepts sulfur from TusA and transfers it in turn to TusE.
What are the official names of this protein?
Sulfurtransferase TusD, tRNA 2-thiouridine synthesizing protein D.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BLC_ECOLI
Sequence: MRLLPLVAAATAAFLVVACSSPTPPRGVTVVNNFDAKRYLGTWYEIARFDHRFERGLEKVTATYSLRDDGGLNVINKGYNPDRGMWQQSEGKAYFTGAPTRAALKVSFFGPFYGGYNVIALDREYRHALVCGPDRDYLWILSRTPTISDEVKQEMLAVATREGFDVSKFIWVQQPGS
What is the function of this protein?
Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions.  Displays a binding preference for lysophospholipids.
What are the official names of this protein?
Outer membrane lipoprotein Blc.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: M2_I85A3
Sequence: MSLLTEVETPTRNGWECKCSDSSDPLVIAASIIGILHLILWILDRLFFKCIYRRLKYGLKRGPSTEGVPESMREEYRQEQQSAVDVDDGHFANIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: RRF_ALTMD
Sequence: MIDEIELDAQERMEKSLVALKGQFSKIRTGRAHPSLLDGIMVPYYGVDTPLKQVANVVAEDSRTLALTVFDKSAIQAVEKAIMQSDLGLNPMSAGGSIRIPLPPLTEERRKDLIRVVRNEAEGGRVAIRNIRRDANGDVKDLLKEKEISEDESRAAEENIQSITNEFIKKVDSLLADKEKELMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_SALG2
Sequence: MSNRKYFGTDGIRGRVGNAPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLESALEAGLAAAGLSASFTGPMPTPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTKLPDDVEEAIEAEMEKEITCVDSAELGKASRIVDAAGRYIEFCKGTFPNELSLNGLKVVVDCANGATYHIAPNVLRELGATVIAIGCEPNGVNINEEVGATDVRALQARVLAEKADLGIALDGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQLRGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKLQEKGWRIGAENSGHVILLDKTTTGDGIVAGLQVLAAMVRNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLENEAVKAVTADVEATLGNRGRVLLRKSGTEPLIRVMVEGEDEAQVTAFAHRIADAVKAV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: SPRT_YERP3
Sequence: MSTLRIPIALQQAVMQCLRHYLQLANQHLGTAYPEPKINYHQRGTNAGSAYLQSFEIRLNPVLLLENKQPFIDEVVPHELAHLLVYRQFGRVAPHGKEWRWMMEQVLKVPASRTHQFEVASVRSKTFNYQCKCQQHALTIRRHNKVLRGESEYRCRQCGEKLQFITINPD
What are the official names of this protein?
Protein SprT.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THID_MYCLE
Sequence: MNYLPAPPPGTTPLRVLSIAGSDSGGGAGIQADMRTMTVLGVHACTAVTAVTIQNTLGVEGFHEIPAEIVASQIKAVVTDIGIQSAKTGMLASSSIIAAVAETWLRLELTTPLVVDPVCASMHGDPLLTGEAMDSLRDRLFPLATVVTPNLDEVRLLVGIDVVDTESQRAAAMALHALGPQWALVKGGHLRSSDRSCDLLYGGSSAGVAFHEFDAPRVQTGNDHGGGDTLAAAVSCALAHGYTVPDAVGFGKRWVTECLRDAYPLGRGHGPVSPLFQRT
What is the function of this protein?
Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.
What are the official names of this protein?
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase, Hydroxymethylpyrimidine kinase, HMP kinase, Hydroxymethylpyrimidine phosphate kinase, HMP-P kinase, HMP-phosphate kinase, HMPP kinase.
What is the protein family that this protein belongs to?
Belongs to the ThiD family.
Protein: ALF1_XANCP
Sequence: MSIEQLAETAQAMVAPGKGIIAIDESTSTIAKRFSGVGIENTEENRRAYRELLLTTPKLSDYISGAILFDETIRQKTKDGVPFAKYMADHGIIPGIKVDKGAQPLAGMPGELVTEGLDGLRARLEEYYTLGARFAKWRAVINIGEDIPSGTCIEANAHALARYAALCQEQGLVPMVEPEVIMDGDHDIETCYEVTEATLRSLFGALYEQNVVLEGTILKASMVISGKGCEEQASVEEVAESTVMCLKSTVPAILPGIVFLSGGQTDEQSTAHLNEMHQLGNLPWPLSFSYGRAMQQAALKLWSKDMTGNYAKAQQIIYERAKENGLAALGKWKG
What are the official names of this protein?
Probable fructose-bisphosphate aldolase class 1, Fructose-bisphosphate aldolase class I, FBP aldolase.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
Protein: ACDH2_AZOSB
Sequence: MNKIKCALIGPGNIGTDLLYKLKRSPVLEPVWMVGIDAASEGLARARELGLKTTADGVDGLLPHVKADGVQIAFDATSAYVHAENSRKLNELGVLMIDLTPAAIGPFCVPPVNLKDHVGRGEMNVNMVTCGGQATIPMVAAVSRVQPVKYGEIVATVSSKSAGPGTRKNIDEFTRTTAGAVEKVGGAKVGKAIIILNPAEPPLIMRDTVHCLTETEPDQQKITESIHAMIREVQKYVPGYKLVNGPVFDGNRVSIYLEVEGLGDYLPKYAGNLDIMTAAGARTAEMFAEEILAGRLTLESNRAVLA
What are the official names of this protein?
Acetaldehyde dehydrogenase 2/3, Acetaldehyde dehydrogenase [acetylating] 2/3.
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: RECF_GRAFK
Sequence: MHLKNLSLLNYKNLKTAEFDFDEKINCLVGNNGVGKTNVLDSIYLLSFGKSYFNPITSQNINHDSDFFVVEGEFKKNDKAEKILASAKKGQKKIIKRNNKAYEKVSDHIGFIPTVIISPADRDLIIEGSETRRKFMDGVISQSDQSYLNKLLQYTKLVSQRNSLLKYFAANNTFERDTLEVYNLQMSSLGQDLFEKRKEFLKEFIPIFNKRYADITNNKEIVDINYKSQLFDNSLANLLEENLQKDMALQYTSVGTHKDDLSFEIEGHPIKKFGSQGQQKSFLIALKLAQFDFIKKISKVNPILLLDDIFDKLDENRVAHIVALVATDELGQIFLSDTHAERTEKVVKSSNQSYKIFKL
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CODY_STRZJ
Sequence: MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNACIINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIFPVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLNFQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITRSVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSBP1_PONAB
Sequence: MAETDPKTVQDLTSVVQTLLQQMQDKFQTMSDQIIGRIDDMSSRIDDLEKNIADLMTQAGVEELEGENKIPATQKS
What is the function of this protein?
Negative regulator of the heat shock response.  Negatively affects HSF1 DNA-binding activity.  May have a role in the suppression of the activation of the stress response during the aging process (By similarity).
What are the official names of this protein?
Heat shock factor-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the HSBP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y3936_METAC
Sequence: MIELGVSLCPFFLAALFEIRGGYLICLWLRNNMRAVFGPLGRLMLAVCGIIPTFQPSHFGRVYAAHGGIFIVFSLIWDLFVDKKIPDRYDHRGNNNVCGCFHYVLRLSLIGRYSVISFCNFQTPRQRISDFFLSRSIKHNFYLFFCNQTLGNYFV
What are the official names of this protein?
UPF0060 membrane protein MA_3936.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CBY3_HUMAN
Sequence: MWASRDHLPEPDLGDAAPPGSPSSFWTSGLPRQERSTSRQRSRGSPSSTCVPYKVHALATFECSATSHASRLWQTLQQFWADHISRPFSPRRPPLRRMPSLSTFYLLDHNTRQAELGLAYGAPCMRLSNQAFVFRGGRWTTESQLARTRSPLLSRTAWGWKAQVQRSKSQVLLEENNYLKLQQELLIDMLTETMARMHLLEKQRNPEVIPTAAARAGQRKMRKRAGASAGVLMIQPCALDSQ
What are the official names of this protein?
Protein chibby homolog 3.
What is the protein family that this protein belongs to?
Belongs to the chibby family.
Protein: RL21_BURCH
Sequence: MYAVIKTGGKQYKVAVGEKLKVEQIPADIDAEITLDQVLAVGEGESIKFGTPLVSGASVKATVVSHGRHAKVTIFKMRRRKHYQKHGGHRQNYTELRIDAINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: CUTA_SALTY
Sequence: MLDVKSQDISIPEAVVVLCTAPDEATAQDLAAKVLAEKLAACATLLPGATSLYYWEGKLEQEYEVQMILKTTVSHQQALIDCLKSHHPYQTPELLVLPVTHGDTDYLSWLNASLR
What is the function of this protein?
Involved in resistance toward heavy metals.
What are the official names of this protein?
Divalent-cation tolerance protein CutA.
What is the protein family that this protein belongs to?
Belongs to the CutA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_BARQU
Sequence: MSKRETTKYKIDRRMGENIWGRPKSPVNRRDYGPGQHGQRRKGKLSDYGVQLRAKQKLKGFYGDISEKQFRKTYEEAARRRGDTGENLIGLLESRLDAVIYRAKFVPTIFASRQFINHGHVNVNGRRTNIQSYRCKPGDVIEVREKSKQLVLVLESVQLAERDVPEYIEADHNQMKATFVRIPAFADVPYAVQMEPNLVVEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: GLK_ECO81
Sequence: MTKYALVGDVGGTNARLALCDIASGEISQAKTYSGLDYPSLEAVIRVYLEEHKVEVKDGCIAIACPITGDWVAMTNHTWAFSIAEMKKNLGFSHLEIINDFTAVSMAIPMLKKEHLIQFGGAEPVEGKPIAVYGAGTGLGVAHLVHVDKRWVSLPGEGGHVDFAPNSEEEGIILEILRAEIGHVSAERVLSGPGLVNLYRAIVKADNRLPENLKPKDITERALADSCTDCRRALSLFCVIMGRFGGNLALNLGTFGGVFIAGGIVPRFLEFFKASGFRAAFEDKGRFKEYVHDIPVYLIVHDNPGLLGSGAHLRQTLGHIL
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUTD_ECO8A
Sequence: MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVCYDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIEHYAVVGHALGALVGMQLALDYPASVTVLISVNGWLRINAHTRRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARVPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPTACSSELHAALPDSQKMVMPYGGHACNVTDPETFNALLLNGLASLLHHREAAL
What is the function of this protein?
Involved in pyrimidine catabolism.  May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.
What are the official names of this protein?
Putative carbamate hydrolase RutD, Aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
Protein: OPSB_CARAU
Sequence: MKQVPEFHEDFYIPIPLDINNLSAYSPFLVPQDHLGNQGIFMAMSVFMFFIFIGGASINILTILCTIQFKKLRSHLNYILVNLSIANLFVAIFGSPLSFYSFFNRYFIFGATACKIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGNFTFKTPHAIAGCILPWISALAASLPPLFGWSRYIPEGLQCSCGPDWYTTNNKYNNESYVMFLFCFCFAVPFGTIVFCYGQLLITLKLAAKAQADSASTQKAEREVTKMVVVMVLGFLVCWAPYASFSLWIVSHRGEEFDLRMATIPSCLSKASTVYNPVIYVLMNKQFRSCMMKMVCGKNIEEDEASTSSQVTQVSSVAPEK
What is the function of this protein?
Visual pigments are the light-absorbing molecules that mediate vision.  They consist of an apoprotein, opsin, covalently linked to cis-retinal.
What are the official names of this protein?
Blue-sensitive opsin, Blue cone photoreceptor pigment.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: METN_SHIDS
Sequence: MIKLSNITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGKSTLIRCVNLLERPTEGSVLVDGQELTTLSESELTKARRQIGMIFQHFNLLSSRTVFGNVALPLELDNTPKDEIKRRVTELLSMVGLGDKHDSYPSNLSGGQKQRVAIARALASNPKVLLCDEATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVISNGELIEQDTVSEVFSHPKTPLAQKFIQSTLHLDIPEDYQERLQAEPFTDCVPMLRLEFTGQSVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHHVKVEVLGYV
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CLINK_MDV1
Sequence: MGLKYFAHLPLELREKIVRDHLQEERKKEFLEKAIEDSCRRHEALLIEDPSPAELNSLSKFLTALSDYVGNQFNTRCLIRWKKDVPSKVKFGFMDEQHHKLYGSMDMDDLSCGELFIPDEEDDLTYEDGVIVRCSQLDQLFKSLGIEIVYIVVSKHCIWAPLSKEIVIK
What is the function of this protein?
Interacts with and disrupts the function of host retinoblastoma-related proteins RBR, which are key regulators of the cell cycle.  Induces transcriptional activation of E2F-regulated S-phase and G2/M-phase-specific genes.  Inactivation of the ability of RBR to arrest the cell cycle leads to the stimulation of viral DNA replication (By similarity).
What are the official names of this protein?
Cell cycle link protein, Clink.
What is the protein family that this protein belongs to?
Belongs to the nanovirus Clink protein family.
Protein: RS15_LEPIN
Sequence: MIATEQKKQIISNFARKAGDTGSTEVQIALIDARIKELNEHFKTHKKDFHSKTGLLRLVGKRKKLLDYLKRTELERYKKLIETLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: OAZ1_HUMAN
Sequence: MVKSSLQRILNSHCFAREKEGDKPSATIHASRTMPLLSLHSRGGSSSESSRVSLHCCSNPGPGPRWCSDAPHPPLKIPGGRGNSQRDHNLSANLFYSDDRLNVTEELTSNDKTRILNVQSRLTDAKRINWRTVLSGGSLYIEIPGGALPEGSKDSFAVLLEFAEEQLRADHVFICFHKNREDRAALLRTFSFLGFEIVRPGHPLVPKRPDACFMAYTFERESSGEEEE
What is the function of this protein?
Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels.  Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome (PubMed:17900240, PubMed:26305948, PubMed:26443277).  Triggers ODC degradation by inducing the exposure of a cryptic proteasome-interacting surface of ODC (PubMed:26305948).  Stabilizes AZIN2 by interfering with its ubiquitination (PubMed:17900240).  Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter.  SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.  Involved in the translocation of AZIN2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol (PubMed:12097147).
What are the official names of this protein?
Ornithine decarboxylase antizyme 1, AZ1, ODC-Az.
What is the protein family that this protein belongs to?
Belongs to the ODC antizyme family.
Protein: CCMA_YERPE
Sequence: MLEAKNLTCIRDDRCLFQQLSFCIAPGEIVQIEGPNGAGKTSLLRILAGLAEADEGQVNWRDKNIRRDRAKYHQDLLFLGHQPGIKSVLTPFENLLFYQSVFQKVDSAAIWQALAQVGLVGYEDLPVSQLSAGQQRRVALARLWLSPAPLWILDEPLTAIDKQGVSTLLALFVQHAAKGGMVLLTTHQDLGAVSHNVRKICLANTQEKSCLSACCAVN
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NSRR_SALEP
Sequence: MQLTSFTDYGLRALIYMASLPDGRMTSISEVTEVYGVSRNHMVKIINQLSRAGFVTAVRGKNGGIRLGKPANTICIGDVVRELEPLSLVNCSSEFCHITPACRLKQALSKAVQSFLKELDNYTLADLVEENQPLYKLLLVE
What is the function of this protein?
Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress.  May require iron for activity.
What are the official names of this protein?
HTH-type transcriptional repressor NsrR.