PharMolix/UniProtQA huggingface dataset:
Protein: YEBC_SALTI
Sequence: MAGHSKWANTRHRKAAQDAKRGKIFTKIIRELVTAAKLGGGDPDANPRLRAAVDKALANNMTRDTLNRAIARGVGGDEDSNMETIIYEGYGPGGTAIMIECLSDNRNRTVAEVRHAFSKCGGNLGTDGSVAYLFSKKGVISFEKGDEDTIMEAALEAGAEDVVTYDDGAIDVYTAWEEMGKVRDALEAAGLKADSAEVSMIPSTKADMDAETAPKLLRLIDMLEDCDDVQEVYHNGEISDEVAATL
What are the official names of this protein?
Probable transcriptional regulatory protein YebC.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGTL1_BRADU
Sequence: MSVGMAAPHAPYACDPDRSRGRLVAEPPSRTRSPFRRDCDRVIHSTAFRRLKYKTQVFVFHEGDHYRTRLTHSLEVAQIARALARQLGLDEDLTETLALAHDLGHPPFGHAGERALDACLKEFGGFDHNAQALRVVAALEHRYPEFDGLNLTWESLEGIVKHNGPLTDRSGAPVGHYREHGIPVGIADYIKVYDLELWSFASLEAQVAAIADDIAYDAHDIDDGLRAGLFDLDDLKAMPLTAAIIAETSAHYPDLEDVRRGAELVRELISHLIGAVFAEAQKNLAATKPQSAQDVRQQSRALIAFPADVAEEEAAIKRFLYQHMYRHKRVMRVMGEAKQILFDLFAKYLKSPAELPPEWLTGAEADNEGDRARRIGNFIAGMTDRFALTEHQRLFDSTPDLR
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: GCSH5_AQUAE
Sequence: MAEVNGCQLPEDRLYYINPDKNAFIWAKEEDGVFTIGLTSVAAAMAGRLVAYTPKKVGKAVKKDKSVATIESGKWVGPVPSPFDGEIVEVNEALKGNPALVNDDPYGQGWIAKVKPANPEEAKSVLVDANKAAELLQPIVQEKGVKCG
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein 5.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: MYB15_ARATH
Sequence: MGRAPCCEKMGLKRGPWTPEEDQILVSFILNHGHSNWRALPKQAGLLRCGKSCRLRWMNYLKPDIKRGNFTKEEEDAIISLHQILGNRWSAIAAKLPGRTDNEIKNVWHTHLKKRLEDYQPAKPKTSNKKKGTKPKSESVITSSNSTRSESELADSSNPSGESLFSTSPSTSEVSSMTLISHDGYSNEINMDNKPGDISTIDQECVSFETFGADIDESFWKETLYSQDEHNYVSNDLEVAGLVEIQQEFQNLGSANNEMIFDSEMDFWFDVLARTGGEQDLLAGL
What is the function of this protein?
Transcription factor involved in cold-regulation of CBF genes and in the development of freezing tolerance.  May be part of a complex network of transcription factors controlling the expression of CBF genes and other genes in response to cold stress.  Binds to the MYB recognition sequences in the promoters of CBF1, CBF2 and CBF3 genes (PubMed:17015446).  Involved in drought and salt tolerance.  May enhance expression levels of genes involved in abscisic acid (ABA) biosynthesis and signaling, as well as those encoding stress-protective proteins (PubMed:19161942).
What are the official names of this protein?
Transcription factor MYB15, Myb-related protein 15, AtMYB15, Myb-related protein Y19, AtY19.
What are the subcellular locations of this protein?
Nucleus.
Protein: OML6_ORYSJ
Sequence: MSCLSRLNASAAPWEPPVARAMAVEQYCPPPQSLLPPPPLPPVAVPTTCGCAACLQGCFVPVGVQAAFPHAAAGCAPPPPVMPVMIVYRVVQPPPPAAHATRCQITEIEDGGGVETAKAVDGDEPQPFIRTVRSTRRRKAAAIRLPKAFRAALLPPPPPPCALGFTATTTSLMIRNIPNKFLKARLMAILDQHCADENGKCHRRGGGGGRSVVKSEYDFFYVPIDFKTGFNKGYAFVNMTTATAARRLRAFLQDHRWDAAMSGKVCDVVPAAIQGLDAFVAHFSASCFPCRTKEFLPVWFEPPRDGEQQTKAHVVGRLVVRPR
What are the official names of this protein?
Protein MEI2-like 6, OML6, MEI2-like protein 6.
Protein: INVF_SALTY
Sequence: MSFSESRHNENCLIQEGALLFCEQAVVAPVSGDLVFRPLKIEVLSKLLAFIDGAGLVDTTYAESDKWVLLSPEFRAIWQDRKRCEYWFLQQIITPSPAFNKVLALLRKSESYWLVGYLLAQSTSGNTMRMLGEDYGVSYTHFRRLCSRALGGKAKSELRNWRMAQSLLNSVEGHENITQLAVNHGYSSPSHFSSEIKELIGVSPRKLSNIIQLADK
What is the function of this protein?
Transcriptional regulator required for the expression of several genes encoding type III secretion system SPI1 effector proteins.  The interaction with SicA is necessary for the activation of sigDE (sopB pipC), sicAsipBCDA, and sopE.
What are the official names of this protein?
Invasion protein InvF, Transcriptional regulator InvF.
Protein: URM1_COCIM
Sequence: MGSHMTGENGQLALLDITVEFTGGLEMLFSNQRKHKISLPSLDITGAPSNIAYLIKYLCQNLMKDERKELFVLDDSVRPGILVLINDADWELEGEEQYRIQQNDNILFVSTLHGG
What is the function of this protein?
Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4.  The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1.  The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
What are the official names of this protein?
Ubiquitin-related modifier 1.
What is the protein family that this protein belongs to?
Belongs to the URM1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGB_COREF
Sequence: MDIIIRADAQEVGKEAAAIMAPFIKQGRTIGLATGSSPLTTYRELIRMYESGELTFKTIQAFLLDEYVGLARDDKNSYFRTIRDEFTAHVDFVDANVHSPDSTDPDPYHAAALYEQKIIDTGVAIQLLGVGVNGHIGFNEPTSALQGPTKVQALHPQTIKDNARFFNDCIENVPTHAMTQGLGTITRAENIIMVATGEAKADAIHRIVEGPLTALCPGSVLQLHADVTIVVDEAAASKLEHADYYRTMERIRL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: MURA2_GEOKA
Sequence: MDKMKIIGGDRLRGTIKVSGAKNSAVALIPAAILADSPVTIEGLPDISDVHILGSLIEEIGGSFSFDGKEAVIDPTNMVSMPLPNGKVKKLRASYYLMGAMLGRFKRAVVGLPGGCHLGPRPIDQHIKGFEALGATVTNEQGAIYLRAEELRGARIFLDVVSVGATINIMLAAVRAKGRTIIENAAKEPEIIDVATLLSNMGAKIKGAGTDVIRIDGVEKLSGCRHAIIPDRIEAGTYMIAAAATNGEVVVDNVIPQHVESLTAKLREMGVRVETGEDQILVCGTDVLKAVDVKTLVYPGFPTDLQQPFTALLTKANGTSVVTDTIYSARFKHVDELRRMNANVKVEGRSAIVTGPVKLQGAKVKASDLRAGAALVIAGLMAEGVTEITGVEHIDRGYSNLVEKLSDIGATIWREKMTDEEIEQVKNA
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2, Enoylpyruvate transferase 2, UDP-N-acetylglucosamine enolpyruvyl transferase 2, EPT 2.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_DESOH
Sequence: MEPYALTIHEARQLLDKKEISSVELTRSVFDRIERVEPKVGAYITLARESALSAAAAADTRLQSGGIAPLTGIPLAVKDLICTTGLRTTCASRMLETFMPPYDATVIEKLKTQGAVITGKVNMDEFAMGSSTEHSALGSTKNPWNLACIPGGSSGGSAASVAADMCLGSLGSDTGGSIRQPASHCGVVGIKPTYGRVSRYGLVAFASSLDQIGVLAKDVTDSALLLSAISGHDPSDSTSVPREVPDYAASCEKGLSGLTIGVCREYINAEGLDPEVADTVNRSIEHMKAQGAACVEVSLPHAQYAVAAYYVIAPAEASSNLARYDGVKYGFRDPEADSLLEMYARTRSRGFGKEVQRRIIIGTYCLSSGYYDAYYRKASQVRSLIADDFKKAFETCDVIVSPVAPTPAFELGAKTEDPLTMYLSDIFTLSANLAGVPGMSVPGGFSSTGLPIGVQLIAGHFNEPALVRCAWNLEQAVNIANKKPAL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: ILK_CAVPO
Sequence: MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICNKYGEMPMDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNGTLNKHSGIDFKQLNFLAKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECPRLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALDMARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKMQDK
What is the function of this protein?
Receptor-proximal protein kinase regulating integrin-mediated signal transduction.  May act as a mediator of inside-out integrin signaling.  Focal adhesion protein part of the complex ILK-PINCH.  This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway.  Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells.  Regulates cell motility by forming a complex with PARVB.  Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.
What are the official names of this protein?
Integrin-linked protein kinase, 59 kDa serine/threonine-protein kinase, Beta-integrin-linked kinase, ILK-1, ILK-2, p59ILK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium. Cytoplasm, myofibril, sarcomere.
Protein: RL5_WIGBR
Sequence: MQLYDFYKKNVLIKLKNKFNYKSIMQVPKIEKITLNMGVGKASFDKKLLEHAVNDLTLISGQKPYITKAKKSIANFKIRQGHPIGCKVTLRGKLMWFFFQKLICIAIPRIRDFRGLPVKSFDGFGNYSLGIKEQIIFPEIDYDKIDKIRGLDITITTNAKSDKEGLALLSAFNFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: TREY_MYCTO
Sequence: MAFPVISTYRVQMRGRSNGFGFTFADAENLLDYLDDLGVSHLYLSPILTAVGGSTHGYDVTDPTTVSPELGGSDGLARLSAAARSRGMGLIVDIVPSHVGVGKPEQNAWWWDVLKFGRSSAYAEFFDIDWELGDGRIILPLLGSDSDVANLRVDGDLLRLGDLALPVAPGSGDGTGPAVHDRQHYRLVGWRHGLCGYRRFFSITSLAGLRQEDRAVFDASHAEVARWFTEGLVDGVRVDHLDGLSDPSGYLAQLRELLGPNAWIVVEKILAVDEALEPTLPVDGSTGYDVLREIGGVLVDPQGESPLTALVESAGVDYQEMPAMLADLKVHAAVHTLASELRRLRRCIAAAAGADHPLLPAAVAALLRHIGRYRCDYPGQAAVLPCALAETHSTTPQLAPGLQLIAAAVARGGEPAVRLQQLCGAVSAKAVEDCMFYRDARLVSLNEVGGEPRRFGVGAAEFHHRAATRARLWPRSMTTLSTHDTKRGEDVRARIGVLSQVPWLWAKFIGHAQAIAPAPDAVTGQFLWQNVFGVWPVSGEVSAALRGRLHTYAEKAIREAAWHTSWHNPNRAFEDDVHGWLDLVLDGPLASELTGLVAHLNSHAESDALAAKLLALTVPGVPDVYQGSELWDDSLVDPDNRRPVDYGTRRVALKALQHPKIRVLAAALRLRRTHPESFLGGAYHPVFAAGPAADHVVAFRRGDDILVAVTRWTVRLQQTGWDHTVLPLPDGSWTDALTGFTASGHTPAVELFADLPVVLLVRDNA
What is the function of this protein?
Catalyzes the conversion of maltooligosaccharide into the non-reducing saccharide, maltooligosyl trehalose (alpha-maltooligosyl alpha-D-glucoside) by intramolecular transglycosylation.
What are the official names of this protein?
Putative maltooligosyl trehalose synthase, (1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: LEU1_CAUVC
Sequence: MTSVPAGAISKRDNVVVFDTTMRDGEQSPGASMSLEEKLELAKILEEMGVDVIEAGFPIASNGDFEAVRQIAELITESTVCGLARAAAGDIDRCAEAVRRAKRGRIHTFISTSPVHMKYKLQMEPDAVLEAITRSVSHARNLVGDVEWSAEDATRTERDFLKRCVEAAIKAGATTINLPDTVGYSYPSEYGELFRDVITSVPGADKAIFSAHCHNDLGLAVANSIAAIEGGARQVEVAINGIGERAGNAALEEIVMALRVRGDHLPYGTSVDPVHITRASRYVSAITGFPVQFNKAIVGKNAFAHESGIHQDGMLKNAETYEIMKPEDVGQGATNLVMGKHSGRHAFREKLKALGYELGQNALNDAFGRFKELADKKKHVFDDDIVALVDDALARGSEKIRVSRLRVVAGTDGQSAELTLDIDGVASTAEATGDGPVDAVFNAIHKIVPHSAALRLFQVHAVTEGTDAQAQVSVRLEEDGRIATGAAADTDTLTASAKAYVNALNNLFARKEKSRPEAAIASGF
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: CAIB_ECOBW
Sequence: MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIENVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFARRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQPMPAFPYTADYFSGLTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNGGEMCPRMSKGKDPYYAGCGLYKCADGYIVMELVGITQIEECFKDIGLAHLLGTPEIPEGTQLIHRIECPYGPLVEEKLDAWLATHTIAEVKERFAELNIACAKVLTVPELESNPQYVARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDIQELVSKGLAKVED
What is the function of this protein?
Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine.  Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA.
What are the official names of this protein?
L-carnitine CoA-transferase, Crotonobetainyl-CoA:carnitine CoA-transferase.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family. CaiB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPG_WOLSU
Sequence: MAKHTFQTEVNQLLDLMIHSLYSNKEIFLRELISNASDALEKLQYLTLTDENLKNLQYTPRIDIHFDEEKKILTLSDTGIGMNESDLVENLGTIAKSGTKSFVSRLSGDKKKDSALIGQFGVGFYAAFMVADKIVVTTKKAGEESAYAWLSEGKGDYEITPCSKESHGTEIKLFLKEEEKEFASRWRLEEIIKKYSDHIPFPIFLHYTQKKNDQEESKEEQVNKAFALWRISKNELKEEDYKEFYKSLSHDSHDPLAWVHIKVEGSQEYTTLFYLPSKAPFDLYRVDYRSGVKLYVKRVFITDDDKELLPSYLRFVRGIIDSEDLPLNVSREILQQNRILANIKSASTKKILAEIENLAKDEEKYEAFFKEFGRALKEGLYGDFENKEKLLELMRFHSSLSPNKKISLQSYKERMKEGQKAIYYLMGENADLLQNSPLLEKFKKREIEVLFFDEEIDSIVMPMVNQYGDLPLKAINSAEADKDFEEESVSEEEKERFKPLLERFEKALSGEIKSVRLSKRLVDSPACVVADEDDPNFAMIKMMRQMGNALGDFPEPKPILELNPEHPMVGKLLALEDEERASDYAHLLLDQAKLLESGSLKDAVGFAKRLNAMLERAI
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPG1_YEAST
Sequence: MKLDSGIYSEAQRVVRTPKFRYIMLGLVGAAVVPTAYMRRGYTVPAHSLDNINGVDTTKASVMGTEQRAAMTKGKSLQEMMDDDEVTYLMFSSIM
What are the official names of this protein?
Stationary phase gene 1 protein.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: RL34_SALTY
Sequence: MKRTFQPSVLKRNRSHGFRARMATKNGRQVLARRRAKGRARLTVSK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: TAAR5_MOUSE
Sequence: MRAVLLPGSGEQPTAFCYQVNGSCPRTVHPLAIQVVIYLACAVGVLITVLGNLFVVFAVSYFKVLHTPTNFLLLSLALADMLLGLLVLPLSTVRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFTVRTALRYIVAGWGIPAAYTAFFLYTDVVERALSQWLEEMPCVGSCQLLFNKFWGWLNFPAFFVPCLIMISLYLKIFVVATRQAQQIRTLSQSLAGAVKRERKAAKTLGIAVGIYLVCWLPFTVDTLVDSLLNFITPPLVFDIFIWFAYFNSACNPIIYVFSYRWFRKALKLLLSREIFSPRTPTVDLYHD
What is the function of this protein?
Olfactory receptor specific for trimethylamine, a trace amine enriched in the urine of male mice, playing a role in social behavior.  Trimethylamine is present at high concentration in the urine of male mice after puberty and acts as an attractant.  This receptor is probably mediated by the G(s)-class of G-proteins which activate adenylate cyclase.
What are the official names of this protein?
Trace amine-associated receptor 5, TaR-5, Trace amine receptor 5, mTaar5, Trimethylamine receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2132_ARCFU
Sequence: MNKGKFALLFTFAACFAVIVFFWLLAVPPENFTADRIVMVLLISPIFAILLAFNLSRFLKQHGYSLRQVHVALEQNIADFIYEFQRLVFIHLMPIAFLGALIFYYGEFTPAIAEFLSLFALIFALSPLLFLGISFFVAMLQVYERVRKKSLLRANFFNFWIWIHLFVILLIIISKVLVQPSELPFQKAYFKALNDGVFNLLIIATMNAIFGVTGRMVAREKFPILLHLSIPLVNSFVAVKILMA
What are the official names of this protein?
Uncharacterized protein AF_2132.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LCL2_PARBP
Sequence: MEIKMFHILIGALLGLLFLATGTRAQFQFFEQMFGGGGHQQQQDHREQNVASDSSWYQRNYDNAHCSDYLCPGTLACVSVPHHCPCQHPDVEDKFELGDGSAICISKGGFKANEAARKVELARKGLL
What is the function of this protein?
Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.
What are the official names of this protein?
Long chronological lifespan protein 2.
What is the protein family that this protein belongs to?
Belongs to the LCL2 family.
Protein: RS21_ECOLI
Sequence: MPVIKVRENEPFDVALRRFKRSCEKAGVLAEVRRREFYEKPTTERKRAKASAVKRHAKKLARENARRTRLY
What are the official names of this protein?
30S ribosomal protein S21, Small ribosomal subunit protein bS21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: VCX1_HUMAN
Sequence: MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEELPSV
What is the function of this protein?
May mediate a process in spermatogenesis or may play a role in sex ratio distortion.
What are the official names of this protein?
Variable charge X-linked protein 1, Variable charge protein on X with ten repeats, VCX-10r, Variably charged protein X-B1, VCX-B1.
What is the protein family that this protein belongs to?
Belongs to the VCX/VCY family.
Protein: RL5_AQUAE
Sequence: MSATETKYVPRLYKKYKEEVVPILQKKFNYKSPMQIPRLQKIVVNMGVGEAVQDIRQLERAVEDLRAITGQQPVITRARKSEAGFKLRKGMPIGCKVTLRKERMWDFLDKLISVALPRVKDFKGLSPRSFDGRGNYAFGIAEQIVFPEIDYDKVDRIRGMDIIINTTAETDEEAFWLLSLLGLPIRSM
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: TRI1_PSEP8
Sequence: MDESNLLQGISMIDLRSPDAILSDYAKRYAHLLPELSPQLQQRMAYMPEPDAPRLPLTKPAWLSDRSCTLTPGQAIDRAQGALLGLAIGDAVGTTLEFRRRDQGQVSDMVGGGPFRLAPGEWTDDTSMALCLADTYASQGKFDFATFADAMVRWYRQGENSANGRCFDIGNVTRRALEGWEAQGLAWMGNLEASTAGNGSLIRLAPTAIFRRHSLSATWWESVTQSSVTHRAIEVSECCKLFGAQLHLALNGADKEEALSPKVRPLQPRALIINAGEYKHKTREQIRSSGYVVDTLEAALWAVWNTDNFRDAILLAANLADDADSVAATAGQIAGALYGVSGMPPEWVAKVAWSRHICELASRLFELAPQGDEMDELLSGSE
What is the function of this protein?
Orphan immunity component of an interbacterial competition system (also called effector-immunity systems); this bacteria does not encode an identifiable cognate effector protein.  Expression of this protein in E. coli partially protects the cells against competition by wild-type S. proteamaculans (PubMed:30343895).  Probably acts as an arginine mono-ADP-ribosylhydrolase, mediating the removal of mono-ADP-ribose attached to arginine residues on proteins.  Probably de-ADP-ribosylates FtsZ and possibly other proteins (Probable).
What are the official names of this protein?
ADP-ribosylarginine hydrolase Tri1, Immunity protein Tri1.
What is the protein family that this protein belongs to?
Belongs to the ADP-ribosylglycohydrolase family.
Protein: GRHL2_MOUSE
Sequence: MSQESDNNKRLVALVPMPSDPPFNTRRAYTSEDEAWKSYLENPLTAATKAMMSINGDEDSAAALGLLYDYYKVPRDKRLLSVSKASDSQEDQDKRNCLGTSEAQINLSGGENRVQVLKTVPVNLCLSQDHMENSKREQYSVSITESSAVIPVSGITVVKAEDFTPVFMAPPVHYPRADSEEQRVVIFEQTQYDLPSIASHSSYLKDDQRSTPDSTYSESFKDGASEKFRSTSVGADEYTYDQTGSGTFQYTLEATKSLRQKQGEGPMTYLNKGQFYAITLSETGDNKCFRHPISKVRSVVMVVFSEDKNRDEQLKYWKYWHSRQHTAKQRVLDIADYKESFNTIGNIEEIAYNAVSFTWDVNEEAKIFITVNCLSTDFSSQKGVKGLPLMIQIDTYSYNNRSNKPIHRAYCQIKVFCDKGAERKIRDEERKQNRKKGKGQASQAQCNNSSDGKMAAIPLQKKSDITYFKTMPDLHSQPVLFIPDVHFANLQRTGQVYYNTDDEREGSSVLVKRMFRPMEEEFGPTPSKQIKEENVKRVLLYVRKENDDVFDALMLKSPTVKGLMEALSEKYGLPVEKITKLYKKSKKGILVNMDDNIIEHYSNEDTFILNMESMVEGFKITLMEI
What is the function of this protein?
Transcription factor playing an important role in primary neurulation and in epithelial development.  Binds directly to the consensus DNA sequence 5'-AACCGGTT-3' acting as an activator and repressor on distinct target genes (PubMed:22696678).  During embryogenesis, plays unique and cooperative roles with GRHL3 in establishing distinct zones of primary neurulation.  Essential for closure 3 (rostral end of the forebrain), functions cooperatively with GRHL3 in closure 2 (forebrain/midbrain boundary) and posterior neuropore closure (PubMed:20654612).  Regulates epithelial morphogenesis acting as a target gene-associated transcriptional activator of apical junctional complex components.  Up-regulates of CLDN3 and CLDN4, as well as of RAB25, which increases the CLDN4 protein and its localization at tight junctions (PubMed:22696678).  Comprises an essential component of the transcriptional machinery that establishes appropriate expression levels of CLDN4 and CDH1 in different types of epithelia (PubMed:20978075).  Exhibits functional redundancy with GRHL3 in epidermal morphogenetic events such as eyelid fusion and epidermal wound repair (PubMed:21081122).  In lung, forms a regulatory loop with NKX2-1 that coordinates lung epithelial cell morphogenesis and differentiation (PubMed:22955271).  In keratinocytes, plays a role in telomerase activation during cellular proliferation, regulates TERT expression by binding to TERT promoter region and inhibiting DNA methylation at the 5'-CpG island, possibly by interfering with DNMT1 enzyme activity.  In addition, impairs keratinocyte differentiation and epidermal function by inhibiting the expression of genes clustered at the epidermal differentiation complex (EDC) as well as GRHL1 and GRHL3 through epigenetic mechanisms (By similarity).
What are the official names of this protein?
Grainyhead-like protein 2 homolog, Brother of mammalian grainyhead, Transcription factor CP2-like 3.
What is the protein family that this protein belongs to?
Belongs to the grh/CP2 family. Grainyhead subfamily.
What are the subcellular locations of this protein?
Nucleus. Membrane. Note=detected at cell-cell contact areas.
Protein: MTNN_YERPP
Sequence: MKVGIIGAMEEEVTLLRDRIENRQTLARAGCEIYTGQLNGIDVALLKSGIGKVAAAMGTTLLLEHCQPDLVINTGSAGGLDSSLKVGDIVVSNEVRYHDADVTAFGYEPGQMAGCPAAFVADEDLIALAENCIQQLKLNAVRGLICSGDAFINGAEPLARIRAAFPTVAAVEMEAAAIGHVCYLFNTPFVVVRAISDVADQASHLSFEEFLVVAAKQSTLMIKAMLTTLAQRG
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.  Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.