PharMolix/UniProtQA huggingface dataset:
Protein: RPOA_MACCJ
Sequence: MIEIEKPRIETVEISEDSKFGKFVVEPLERGYGTTLGNSLRRILLSSLPGAAVKNIEIEGVLHEFSAIENVVEDVTSIIMNIKKLALKIYSDEDKTLEIDVKDEGVVTAKDIMHDSDVEILNPDLKIATVSKGGHLKMRLIANAGRGYTLAEDNNTSDLPIGVIPVDSIYTPVERVNYQVENTRVGQSTNFDKLTLDVWTDGSITPQEAISLGAKIMTEHLNIFVDLTDEAQNAEIMIEKEEDHKEKVLEMSIEELDLSVRSYNCLKRAGINSVQELADKSEADMMKVRNLGRKSLEEVKFKLEDLGLGLRKED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: HUTU_FERNB
Sequence: MPEVIRAPRGTQLTCKSWQTEAAMRMLMNNLDPEVARDPANLIVYGGKGKAARNWDCFYKIVETLKKLENDETLLIQSGKPVAVWKTHEWAPRVLIANSNLVPKWATWEYFNELEVRGLIMYGQMTAGSWIYIGTQGILQGTYETFYAVAKKYFGGTLKGKLVLTAGLGEMGGAQPLAVTMNDGVVIAVEVDKRMIDRRIQTGYLDTWTDNLDEALRLAKEALKEGRPLSIGLLGNAAEVHPELVRRGIIPDVVTDQTAAHDPLNGYVPAGISFEEALKLRKENPEKYLEMVYDSVVKHIEAILEMQRQGAKVFEYGNNIRRLALDHGVKDAFNIPGYVPEYIRDLFSEGKGPFRWVALSGKPEDIYKTDQKVLELFGEDEHLRKWIDMAQKKVKWQGLPARICWLGQGQRAEMGLAMNEMVRKGELEAPIVIGRDHHDTGSVASPYRETEAMKDGSDAIADWPLLNAMLNVASGATWVSIHHGGGVGIGYSIHAGVVIVADGTELTRQKLERVLTNDVGMGVVRHADAGYEIAIQTAKKHGIRMPMMD
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARB_LACP3
Sequence: MPKRQDIHKILVIGSGPIIIGQAAEFDYSGTQACLALREEGYEVVLVNSNPATIMTDTEIADRVYIEPLTVEFVSQILRKELPDAILPTIGGQIGLNLAMKLSNTGILDELGIELLGTKLTAIDQAEDRELFKNLMQKLHEPVPESAIANNIEEAQQFADKIGFPVIIRPAFTMGGTGGGIANNEKELAEIAENGLNLSPVTQVLVERSIAGYKEVEFEVMRDAADSAIVVCNMENFDPVGVHTGDSMVFAPTQTLTDKEVQMLRDAALKIIRALKIEGGCNVQFALDRNSFKYYVIEVNPRVSRSSALASKATGYPIAKMAAKIAVGLHLDEIKNPVTKKTWAEFEPALDYVVTKLPRFPFDKFENGDRTLGTQMKATGEVMAIGRTLEESLLKAVRSLEVGLIHPERPAFAKLSDDELSKQIIQANDERLFYLAEAFRRDYTIEEVAELSKMNPFFLDKIKHIVELERELAAHKADLGLLAEVKRYGFADEEIAKLWGLHADQVRQMRKEQKILPVYKMVDTCAGEFASDTPYYYSTYESSTESVKSDKPSVLVIGSGPIRIGQGVEFDYATVHSVKAIQKAGYEAIIMNSNPETVSTDFSIADKLYFEPLTLEDVLNVIDLEQPEGVIVQFGGQTAINLAEPLANRGIKILGTSVEDLNRAEDRDLFDQVIKSLKLPQPEGGTATDKAGALAVADKIGYPVLVRPSYVLGGRAMEIVHDATELDNYIDRAVSVSHDHPVLIDHYLVGKECEVDCISDGDTVVLPGIMEHIERAGIHSGDSMAVYPPQTFSQDIIDQITDATIKLSRTLNCIGLMNVQFIIHAGKAYVIEVNPRASRTVPFLSKVTNIKLAQVATLAILGLSLKEQGFETGLLPNQSGIHVKSPVFSFSKLNHVDSLLGPEMKSTGEVMGSDTTLAKALYKAFEAAGMHLPQFGRALITVKDADKAEATALAKRFREVGYQLVATSGTAKAFEKTGITVSTIEKLDSGQETILEDIANRKIQLVINTMSADKKVSSDGFRIREAAIEHGVPLMTSLDTAGAILKVLELQAFSISPIKS
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: AROL_YERPA
Sequence: MTQTIFMVGARGAGKTTIGKALAQALGYRFVDTDLFMQQTSQMTVAEVVESEGWDGFRLRESMALQAVTAPKTVVATGGGAVLSSENRAFMRDHGRVIYLRASAAVLAKRLAEDPEEAQRPSLTGKPIVEEILDVLASREALYQDVAHHVLDGTQTPSLVVEQILQMLTGEMVK
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase 2, SK 2.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family. AroL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PBIR1_HUMAN
Sequence: MAQEKMELDLELPPGTGGSPAEGGGSGGGGGLRRSNSAPLIHGLSDTSPVFQAEAPSARRNSTTFPSRHGLLLPASPVRMHSSRLHQIKQEEGMDLINRETVHEREVQTAMQISHSWEESFSLSDNDVEKSASPKRIDFIPVSPAPSPTRGIGKQCFSPSLQSFVSSNGLPPSPIPSPTTRFTTRRSQSPINCIRPSVLGPLKRKCEMETEYQPKRFFQGITNMLSSDVAQLSDPGVCVSSDTLDGNSSSAGSSCNSPAKVSTTTDSPVSPAQAASPFIPLDELSSK
What is the function of this protein?
Acts as an inhibitor of serine/threonine-protein phosphatase 2A (PP2A) activity (PubMed:27588481, PubMed:33108758).  Potentiates ubiquitin-mediated proteasomal degradation of serine/threonine-protein phosphatase 2A catalytic subunit alpha (PPP2CA) (PubMed:27588481).  Inhibits PP2A-mediated dephosphorylation of WEE1, promoting ubiquitin-mediated proteolysis of WEE1, thereby releasing G2/M checkpoint (PubMed:33108758).
What are the official names of this protein?
PPP2R1A-PPP2R2A-interacting phosphatase regulator 1, PABIR family member 1.
What is the protein family that this protein belongs to?
Belongs to the FAM122 family.
Protein: YCEH_ECOSE
Sequence: MKYQLTALEARVIGCLLEKQVTTPEQYPLSVNGVVTACNQKTNREPVMNLSESEVQEQLDNLVKRHYLRTVSGFGNRVTKYEQRFCNSEFGDLKLSAAEVALITTLLLRGAQTPGELRSRAARMYEFSDMAEVESTLEQLANREDGPFVVRLAREPGKRESRYMHLFSGEVEDQPAVTDMSNAVDGDLQARVEALEIEVAELKQRLDSLLAHLGD
What are the official names of this protein?
UPF0502 protein YceH.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: LYSY_CENSY
Sequence: MKVGVVGASGYVGGETLRLLVNHPDVEIAAVTSRQHVGEYLHRVQPSLRGFTDLTFSELDYDRLSDSCDLVFTAVPHGTATDIVRALYDRDIKVIDLSADYRLHDPADYTKWYGWEHPHPDYLSKSVFGIPELHREEIRSAKLVSCPGCMAVTSILALAPPVREGLVDTEHIVVDSKIGSSGAGAGAGTAHAMRAGVIRPYKPAKHRHTGEIEQELSGIAGKKIRVSMSPHAVDVVRGILCTNHVFLTREASEKDLWKMYRQAYGEERFVRLIRDKKGLYKFPDPKFLVGSNFCDIGFDLDEDNNRLVAISASDNLMKGAAGSAIQNMNIMAGLDEMSGLRYTPLTPV
What is the function of this protein?
Involved in both the arginine and lysine biosynthetic pathways.
What are the official names of this protein?
Putative [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHSE_STRA5
Sequence: MRIIVPATSANIGPGFDSIGVALSKYLIIEVLEESTEWLVEHNLVNIPKDHTNLLIQTALHVKSDLAPHRLKMFSDIPLARGLGSSSSVIVAGIELANQLGNLALSQKEKLEIATRLEGHPDNVAPAIFGDLVISSIVKNDIKSLEVMFPDSSFIAFIPNYELKTSDSRNVLPQKLSYEDAVASSSVANVMVASLLKGDLVTAGWAIERDLFHERYRQPLVKEFEVIKQISTQNGAYATYLSGAGPTVMVLCSKEKEQAIVTELSKLCLGGQIQVLNIERKGVRVEKR
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_CLOBL
Sequence: MRTAIIAGNWKMNKTVKEAVELVKELKPLVKDAKCDVVVCPTYVCLPAVLEEVKGSNIKVGAQNMHFEESGAYTGEIAPKMLEELGVHYVIIGHSERRQYFNETDETVNKKVKKAFEHNLIPIVCCGESLEEREGNITEKVLEGQIKVGLKELSKEQVEKLVIAYEPIWAIGTGKTATDEQANETIGYIRTVVKDMYGENVADKVRIQYGGSVKPGTIKAQMAKEEIDGALVGGASLKAEDFAAIINY
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PER_DROEQ
Sequence: SSTETPPSYNQLNYNENLLRFFNSKPVTAPVELDPPKVESSYVSSARGEDARSTLSPVQGFEGSGGSGSSGNFTTGSNLHMSSVTNTSNAGTGTSGTGNSGDGGGGGGADGTGSGAAPPVTLTESLLNKHNDEMEKFMLKKHRESRGRSGEKNKKSANEAMKMLEYSGPGPGHGHGIKRGGSHSWEGEANKPKQQLTLNTSGGGGGGGGGGGMPLFLDMTHASSSSQNKGLAGVGVGGAGGVVGGGSGTGLGGNGNVGSGNGNNNQPSTNQYTQSRLPCTQNINLWPPFSVGITTPTSVLSSHTAVPPSSFSPQHSLFPTFYYIPASIAASSPSGTNTNPNRPHKHAHVHNSSEKPSTSQAAAATMPLQYMTGVMYPHPSLFYTHPAAAAATAMV
What is the function of this protein?
Essential for biological clock functions.  Determines the period length of circadian and ultradian rhythms; an increase in PER dosage leads to shortened circadian rhythms and a decrease leads to lengthened circadian rhythms.  Essential for the circadian rhythmicity of locomotor activity, eclosion behavior, and for the rhythmic component of the male courtship song that originates in the thoracic nervous system.  The biological cycle depends on the rhythmic formation and nuclear localization of the TIM-PER complex.  Light induces the degradation of TIM, which promotes elimination of PER.  Nuclear activity of the heterodimer coordinatively regulates PER and TIM transcription through a negative feedback loop.  Behaves as a negative element in circadian transcriptional loop.  Does not appear to bind DNA, suggesting indirect transcriptional inhibition (By similarity).
What are the official names of this protein?
Period circadian protein.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, perinuclear region. Note=Nuclear at specific periods of the day. First accumulates in the perinuclear region about one hour before translocation into the nucleus. Interaction with Tim is required for nuclear localization (By similarity).
Protein: MZM1_CANGA
Sequence: MIPEALRKQALIAYKHGLRATRVAFDGDNRVLLAARAEMRKGMENPDSSKTTQEQIQHLEEVATFLKRNLVQGQKIEGEEKYHLKIHKDIELGDNESIKQPTKFKARPFKKCSDN
What is the function of this protein?
Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex.  Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.  Modulates the mitochondrial matrix zinc pool (By similarity).
What are the official names of this protein?
Mitochondrial zinc maintenance protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. MZM1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PUR5_HAHCH
Sequence: MTASNDKPSLSYRDAGVDIDAGNALVQRIKGAAQATRRPEVMAGLGGFGALFELPKGYQEPVLVSGTDGVGTKLRLAMQMNKHDTIGIDLVAMCVNDLIVQGAEPLFFLDYYATGKLSVDVAATVVTGIGEGCSQAGCSLVGGETAEMPGMYEGDDYDLAGFCVGIVEKSKIIDGSLVKPGDVLIGLASSGVHSNGYSLVRKIVEVSGADLNQPFGDATLGEALLAPTRIYVKPLLELIRQTPVHALSHITGGGLLENLPRVLPAHAKAVVDVNAFEMPELFNWLQKNGNVAWNEMFRTFNCGIGMVVCVPADSADKALELLSAAGETVFRIGSIETHTEEEPVVELKGLVD
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_THEVB
Sequence: MGQKIHPIGFRLGITQDHRSRWYADSDRYPELLQEDHRIRTFINQQLANAGIAEVRIERKADQVELQIRTARPGVVVGKGGQGIEELRKQLRQMLPANRTIKVNVVEVNRVDAEASLLAEYITQQLERRVAFRRAVRQAIQRAQRAGIEGIKVQVAGRLNGAEIARTEWTREGRVPLHTLRADIDYAYRTARTIYGILGVKVWIFKGEVLPGQTEAVPREATRRSPQRRLPQFENRSN
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RL11_RUBXD
Sequence: MGRGRGKRVVRKLKLQIPGGQANPAPPVGPALGQAQVNIGEFVRQFNDATRDRMGQLIPVEITVYEDRSFTFVTKTPPAAFLLKQAAGVEKGSGEPNRSAAGRVSRAQVEEIARTKMPDLNAADVEAAVKIIEGTARSMGIKVEQ
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: MUT7_AEDAE
Sequence: MSKSNNVAPPCRQDQLGFVPAGYDSDNNSEDEMLMVMPNASTSSGESGRCFDDERIKIVPHIGWRAGIGDRDFDIELDENIANWFEGFRDSFKTFKKGPLISQRLQMFYMNTRNPYEWSLKLFANCPDHNSPKSNSLAYTVLEEMRNFKKHYNLGTDQLVDDNLRMVAFNFVAKQGHCLLFRMVVDIFEFLQCRDLFIPKVREMIARKQYKEAGQIAIDLELFEEFDEHDFVMPLFMQDKISIAEDYLNKAERLQGPVVQLLDSFFDKRQSVESHCSRYITEHEVTDVYYSKLHQKPLSKLVQRLAKNYNIPRQFTPNVNKMKNFGALQFLVHKRYYEKSLNKDSWDEMVRDTVSETDRELQLELVCLCSNFNDQPEAAKWAFHYQLKRSDLPLLVQDYILEQEGNKQAPRTDFDDEQWDAPDSEPAHTLRLDESHVHLVDSKDKFYAMLSDLCRQSMIAFDSEWKPTFGGANEVSLIQLATWDDVYMIDVMVSQLEPLDWAALAKNVFNRDDVLKLSFAPSTDISMFQKALPSFNVMYSSQSTSAILDLQLLWRHVERFDSFRFPYHEESVNQNLANLVRLCLGKKLDKSNQFSNWAQRPLRKEQLRYAALDAFCLLEIYDAIEKQLTHIQLDPNEILNALLNDVRPPSDSGTRRAGRQDGSSGSRRNHRDKYNKRHAYAEDSNSGNSSRAHQNRTKSKGAGLREQQTFEGPNTKSVL
What is the function of this protein?
Possesses 3'-5' exoribonuclease activity.  Required for 3'-end trimming of AGO1-bound miRNAs (By similarity).
What are the official names of this protein?
Exonuclease mut-7 homolog, Exonuclease 3'-5' domain-containing protein 3 homolog.
What is the protein family that this protein belongs to?
Belongs to the mut-7 family.
Protein: BIOF_SODGM
Sequence: MADGWMARIDDALAQRRREQTYRERWALSGGNDRLIRDGDRQYLNFSSNDYLGLARHPEVIAAWQQGAAQAGVGAGGSGHVTGYGLHHQRLEQRLADWLGFPRALLFTSGFAANQALVGALTASGDHILADRLSHASLLEAAMHSPATLRRFAHNDADALQRLLRRDCAGNRLVITEGVFSMDGDRAPLPALAEITRAAGCWLMVDDAHGIGVVGEEGRGCAWAPAGRPDLLVVTFGKAVGVSGAAVLCATPVAEYLLQFARHLIYSTAPPPAQIAAIDAALTVVRRGDALRQRLWDNIVRFRRGAAALGFALAPSDTAIQPLVIGDNLRTLQLAQRLRERGVWLTAIRPPTVPPGSARLRITLTSAHLADDIDTLLEALSDAQLQNA
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: SECY_TRICV
Sequence: MKQTDDKDSLLNRLLLSLGILLFIRMGTFLPVPGIDHGHLEFYIERHFRLRTLVSTFAGDNTVVVGLFTLNIFPYINASIIMQLLVSLLPGLSKLQKEGGAEARRSINSLTRLLTLGWSLIQSTSVAFYLKRALFEWNLVLAFEIVIWLTTGAMIVLWLSEIITEYGLGNGPSLLIYTNIVSSLPGFVKQVITESSGKVPIGSWLLSGFVLFVALYGIVLLQEGMRKVYLISSKQLNQTSLPFSGSSNLESGYYIPLRFNQAGVMPIILTTAVLVIPTFIYNLGLLRILTPLITLPVFVKSYKIIYWVSYFVLILLFSLFYSTIVVNPKDLSDELQKMAVSIPGIRPGVETTFYLKQVMKRVTLLGAIMLALLATLPNIIQAILSLSGFTNLGTTSLLILVGVILDLTREMRSIILSNIYYDMFD
What is the function of this protein?
The central subunit of the protein translocation channel SecYE.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: YQGF_RALSO
Sequence: MPEPARPAPAPVPVHGTLLAFDYGEKRIGVALGNSITRSARALEVIPNRSVEYRFTQITRLVNAWQPVGFVVGMPVHPEGEDQPMIKLAKRFGNQLHGRYGLPVTWVDERYSSIAAQDAGATDDVLDAEAARIILQQFFDESHA
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAX1_ARATH
Sequence: MAGIVTEPWSVAENGNPSITAKGSSRELRLGRTAHNMSSSSLRKKSDLRVIQKVPYKGLKDFLSNLQEVILGTKLAILFPAIPAAIICTYCGVSQPWIFGLSLLGLTPLAERVSFLTEQLAFYTGPTLGGLLNATCGNATELIIAILALTNNKVAVVKYSLLGSILSNLLLVLGTSLFCGGIANIRREQRFDRKQADVNFFLLLLGFLCHLLPLLVGYLKNGEASAAVLSDMQLSISRGFSIVMLISYIAYLVFQLWTHRQLFDAQEQEDEYDDDVEQETAVISFWSGFAWLVGMTLVIALLSEYVVATIEEASDKWNLSVSFISIILLPIVGNAAEHAGAVIFAFKNKLDISLGVALGSATQIGLFVVPLTIIVAWILGINMDLNFGPLETGCLAVSIIITAFTLQDGSSHYMKGLVLLLCYFIIAICFFVDKLPQKQNAIHLGHQAMNNVVTATGGGVFSS
What is the function of this protein?
Vacuolar cation/proton exchanger (CAX).  Translocates Ca(2+) and other metal ions into vacuoles using the proton gradient formed by H(+)-ATPase and H(+)-pyrophosphatase.  Involved in ion homeostasis in association with CAX3.  May play a role in cold-acclimation response.
What are the official names of this protein?
Vacuolar cation/proton exchanger 1, Ca(2+)/H(+) antiporter CAX1, Ca(2+)/H(+) exchanger 1, Protein CATION EXCHANGER 1, Protein RARE COLD INDUCIBLE 4.
What is the protein family that this protein belongs to?
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. Cation/proton exchanger (CAX) subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast.
Protein: THIC_BORA1
Sequence: MNANPKFLAATAEVDAAAVAPLPKSRKIYETGSRPDIRVPFREIEQQDTPTMFGGERNPPLTVYDTSGPYTDPQAHIDIRRGLPELRRAWIEERGDVELLAGPTSDYGRARLQDPQLTAMRFDLRRPPRRAKDGANVTQMHYARRGIVTPEMEYVAIRESLRREHYIESLRASGPEGEKMARRLLRQHPGQSFGAAIPAAITPEFVRDEIARGRAIIPANINHPEVEPMIIGRNFLVKINANIGNSAVSSGIGEEVEKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVDGKAEALTWEIFRDTLIEQAEQGVDYFTIHAGVRLPFIPMTADRMTGIVSRGGSIMAKWCLAHHKESFLYERFEEICEIMKAYDVSFSLGDGLRPGSGYDANDEAQFAELKTLGELTQVAWKHDVQVMIEGPGHVPMQMIKENMELQLEHCHEAPFYTLGPLTTDIAPGYDHITSGIGAALIGWYGTAMLCYVTPKEHLGLPNKKDVKDGIITYKIAAHAADLAKGHPGAAVRDNALSKARFEFRWDDQFNLGLDPDTAKEFHDETLPKDSMKVAHFCSMCGPHFCSMKITQDVREYAASQGVSAQQALTQGMQEKAIEFVKKGAEVYHRS
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: HYTL_TITSE
Sequence: MKMMIAIVFVSILLLMFSLSSTAMGMETEQQNMEERADVDFTGIADSIIKKIKETNAKPPARFDPATFGENED
What is the function of this protein?
May potentiate the hypotensive effect of bradykinin.
What are the official names of this protein?
Hypotensin-like peptide.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPG_ECOL6
Sequence: MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRPYAETMRKVIGHLAHGNLEYKHPYLEDRDVKRVGYLVVSTDRGLCGGLNINLFKKLLAEMKTWTDKGVQCDLAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAYDEGRLDKLYIVSNKFINTMSQVPTISQLLPLPASDDDDLKHKSWDYLYEPDPKALLDTLLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQELTEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity).
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: COXX_STRCO
Sequence: MTAVESRPAGVIGTSQSPSHRPFGARVKAFVALTKPRIIELLLITTVPVMFLAEQGVPNLKLVLLTCVGGYLSAGGANALNMYIDRDIDALMDRTSQRPLVTGMVSPVECLVFGITLAIVSTLLFGFTVNWLSAWLSLGALLFYVVVYTMILKRRTSQNIVWGGIAGCLPVLIGWSAVTNSMSWAPVILFGVMFFWTPPHYWPLSMKVKEDYARVGVPMLPVIASNKVVARQIVIYSWVMVVVSLLLQPLGYTGWFYTAVALAAGGMWLWEAHGLQNRAKAEVTGGKLKEMRLFHWSITYVSVLFLAIAVDPFLR
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YWS6_CAEEL
Sequence: MLRVVLFAAILVFSIANSEIIDKSLEQSGPIQDSSNFALAVNGEELPTDIALEGQSEVMIRAKRYYGCGCGCGCATVAAVSPVPCGGCCGCGYGK
What are the official names of this protein?
Uncharacterized protein B0310.6.
Protein: NLE1_PONAB
Sequence: MAAAVADEAVARDVQRLLVQFQDEGGQLLGSPFDVPVDITPDRLQLVCNALLAQEDPLPLAFFVHDAEIISSLGKTLESQAVETEKVLDIIYQPQAIFRVRAVTRCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLMRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWRR
What is the function of this protein?
Plays a role in regulating Notch activity.  Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity.  Required during embryogenesis for inner mass cell survival (By similarity).
What are the official names of this protein?
Notchless protein homolog 1.
What is the protein family that this protein belongs to?
Belongs to the NLE1/RSA4 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RM10_MOUSE
Sequence: MAAAVAGILRGGLPPRAAWLPTLQTVRHGSKAVTRHWRVMHFQRQKLMAITEYIPPKPAINPRCLPPPPKPPKEESGLVRLLRQDIVAVFRDNRMIAVCQNVALSAEDKLLLRHQLRKHKIFIKVFPSQVLKPFLENSKYRNLLPLFVGHNLLLVSEEPKVKEMVRVLKSVPFLPLLGGCVDDTILSRQGLVDYAKLPSLDQLQGQLVGGLTHLMAQTRYLLQHQPVQLTSLLDQYVKEQNEGDCATSANEKLHPPDPAPDA
What are the official names of this protein?
39S ribosomal protein L10, mitochondrial, L10mt, MRP-L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PAU6_YEAST
Sequence: MVKLTSIAAGVAAIAATASATTTLAQSDERVNLVELGVYVSDIRAHLAQYYMFQAAHPTETYPVEVAEAVFNYGDFTTMLTGIAPDQVTRMITGVPWYSTRLKPAISKALSKDGIYTIAN
What are the official names of this protein?
Seripauperin-6.
What is the protein family that this protein belongs to?
Belongs to the SRP1/TIP1 family. Seripauperin subfamily.
Protein: SHE2_YEAST
Sequence: MSKDKDIKVTPGTCELVEQILALLSRYLSSYIHVLNKFISHLRRVATLRFERTTLIKFVKKLRFYNDCVLSYNASEFINEGKNELDPEADSFDKVILPIASMFVKCVETFDLLNYYLTQSLQKEILSKTLNEDLTLTAESILAIDDTYNHFVKFSQWMIESLRIGSNLLDLEVVQFAIKCADEDGTNIGETDNIFLQEILPVNSEEEFQTLSAAWHSILDGKLSALDEEFDVVATKWHDKFGKLKN
What is the function of this protein?
RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease.  Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell.  Recruits the MYO4-SHE3 complex to the ASH1 mRNA.  Recruits also LOC1 and PUF6 to ASH1 mRNA, which are required for translational repression of this mRNA.
What are the official names of this protein?
SWI5-dependent HO expression protein 2.
What is the protein family that this protein belongs to?
Belongs to the SHE2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and cytoplasm and is exported in an mRNA-dependent manner (PubMed:12499354, PubMed:14561888) (PubMed:18566598). The presence in the nucleus is essential for PUF6 and LOC1 to bind the ASH1 mRNA.
Protein: Y619_RALPJ
Sequence: MASPDALINLTNQFLIAMPGMADSTFSGTVVYMCEHNERGALGLVINRPIDIDLATLFDKIDLKLEIHPLAEQSVYYGGPVQTERGFVLHDATGAYSSSLAVPGGLEMTTSKDVLEAVAQGGGPHRFILTLGYAGWSAGQLEDEISRNGWLTVQADPEIIFNVPPEERFAAALNLLGINPAMLSGEAGHA
What are the official names of this protein?
UPF0301 protein Rpic_0619.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.