PharMolix/UniProtQA huggingface dataset:
Protein: CYB_DENPO
Sequence: MSNQHILLTSNLLPVGSNISTWWNFGSMLLTCLILQITTGFFLAIHYTANINLAFSSVIHITRDVPHGWIMQNLHAIGASMFFICIYIHIARGLYYGLYLNKEVWLSGTALLILLMATAFFGYVLPWGQMSFWAATVITNLLTAIPYLGSALTTWLWGGFSINDPTLTRFFALHFILPFTIISMSSIHIILLHNEGSNNPLGTNPDIDKIPFHPYHSYKDMLMITIMITFMLLILSFSPDLMNDPENYSKANPLITPQHIKPEWYFLFAYGILRSIPNKLGGTLALFMSIAILMTAPFTHTSYTRSMSFRPLTQTMFWILIATFITITWTATKPVEPPFISISQVTSIIYFSFFIINPLLGWVENKLSTLNN
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RPOA_NATTJ
Sequence: MIEIEKPQIECHEMNEESTYGKFVIEPLERGYGTTLGNSLRRILLSSLPGAAVTSVKIDGVLHEFSSIPGVVEDTTEIVLNLKRLALKIHSDENQVLTLEKEGKGPVTAGDIQAGSDVDVINPELHIATLSEDTRLYMEITAKNGRGYVRAERNKEPEQPIGLIPVDSVFTPVTKANFYVDDTRVGQVTDYDRLTLEVWTDGSLKPDEAVSMSAKIMQEHLDLFINLTEKATDMEVMVEKEEDNKEKIMELSIDELDLSVRSYNCLKRAGINTIGELTQKTPEDMMKVRNLGKKSLEEVKNKLTELGLSLKDSKE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: GCSPB_CHLTE
Sequence: MKEQLIFDLSRSGRKGYSLSPLDIPERPADELLPSKFLRKEPAELPEMAESEVVRHFIRLSNLNYHVDKNMYPLGSCTMKYNPKINDYTCDLPGFASMHPLQPESTSQGALQLMYELAEMLKEIAGMKAVTLQPAAGAHGELTGILLIKKYHEKLGNKRHKLLVVDSAHGTNPASAALGGYECVSVKCDESGCTDMGDLRAKLDGEVAALMLTNPNTVGIFEKQIPEIEKLVHGNGSLLYMDGANMNALLGITRPGDMGFDVMHYNLHKTFSAPHGGGGPGSGPVGVSERLVEFLPVPVIEKFEKDGQTRYRLNSSKPNTIGRMMNFYGNFSVLVRAYTYIRMLGADGLRRVSENAIINANYLLQRLVEHYALPYPRPVMHEFCLSGDRQKKEHGVRTLDIAKRLLDYGYHAPTVYFPLIVSEALMIEPTETEAKETLNAFADAMIAIAEEAKSNPDLIKSAPTTTPVKRLDEAQASRQLNICCQH
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: PURA_BUCAP
Sequence: MNTNIVILGTQWGDEGKGKIVDFLSSNSSYVVRYHGGHNAGHTLVVNGKKIILHLIPSGLLYPNVIGIISNGVVISPFELVKEIRMLEKNNHFINERLFISESAPLILPYHIAIDLAREKQLGINAIGTTGRGIGPAYEDKVARRALRVGDLKNTQKLSTKLKVIVDYYNHQLVSFYKQNPISYKEILKDLLKVKDLIYNMIKDTSAILHKAIEDKKRIIFEGAQGTLLDIDHGTYPYVTSSNSTTGGIITGTGVGPKNLGYILGITKAYTTRVGKGPFPTELFDDIDSYLSKKGQEFGSTTGRKRRTGWLDGVALRYSVKINSLSALCITKLDVLDDLKEIKICTSYKDVNTKKIYKDFPIFNLEDVTPVYEVHPGWMKKTSGIKKIEDLPKAACNYINRIEEIAQVPIDIISTGPDRSDTILLKSLFF
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_BORPA
Sequence: MSTLVESPVPSNDSQAAAPAAYDPTQKQKSQAKTARIPIKVVAAEKLKKPEWIRVRAAAPGSRFYDIKRILREHNLHTVCEEASCPNIGECFGKGTATFMIMGDKCTRRCPFCDVGHGRPDPLDTQEPENLARTIAALKLSYVVITSVDRDDLRDGGAAHFVECIAKVREYSPDTRIEVLVPDFRGRLDRALHILNSGPPDVMNHNLETVPRLYKQARPGSDYAHSLKLLVEFKKLHPEVPTKSGLMLGLGETDEEILQVMRDMREHNVDMLTIGQYLQPSEHHLPVLRYVHPDTFAMFEREAYAMGFTHAAVGAMVRSSYHADQQAHAAGVN
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDHP_BOVIN
Sequence: MAGYLRVVRSLCRASGSGSAWAPAALTAPNLQEQPRRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVVDRAGTFKVVFTPKDGSGPKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQAIFEKHYKTEFDKHKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKSNLDRALGQQ
What is the function of this protein?
Plays a role in intermediary metabolism and energy production.  It may tightly associate or interact with the pyruvate dehydrogenase complex.
What are the official names of this protein?
Isocitrate dehydrogenase [NADP], mitochondrial, IDH, ICD-M, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TTCA_BRUA2
Sequence: MNAFDADITEHADSSGCHPLFRDVPATVEFNKLRKRLLRLTRQAIEDFAMVKPGDRWMVCLSGGKDSYGLLALLLDLKWRGLLPVELLAVNLDQGQPNFPKHILPDFLTRYGIEHRIEYQDTYSIVTDKLPETSTYCSLCSRLRRGNLYRIAREEGCSAIVLGHHREDILETFFMNLFHGGRLAAMPPKLLNDEGDLMVFRPLAYAAEDDLEKFANAMQFPIIPCDLCGSQDGLQRNAMKAMLIDIEKRMPGRKDTMIRALTNVRPSHLLDRKLFDFAGLMANGEKGSDDALW
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDHY_ECOLI
Sequence: MNPVDRPLLDIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQEDIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTNFNDGSVGTFFSRIKIHRNYFFGDNGVGSGGGLYGDLNYTADTCRQCKEPQCMNVCPIGAITWQQKEGCITVDHKRCIGCSACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV
What are the official names of this protein?
Uncharacterized ferredoxin-like protein YdhY.
Protein: YQGF_BACVZ
Sequence: MRILGLDLGTKTLGVALSDEMGWTAQGIETIKINEAEGDYGLDRLSELMKDYNVEKIVLGFPKNMNGTIGPRGEASQTFAKLLETAYNVPVVLWDERLTTMAAEKMLIAADVSRQKRKKVIDKMAAVMILQGYLDSLN
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_RHORT
Sequence: MMAAPRRPFFRRRKTCPFSGAGAPKIDYKDIKLLLRFVSERGKIVPSRITAVSAKKQRELARAIKRARFLSLLPYVLK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: VTF3S_VARV
Sequence: MFEPVPDLNLEASVELGEVNIDQTTPMIKENIGFISRSRRLFAHRSKDDERKLALRFFLQRLYFLDHREIHYLFRCVDAVKDVTITKKNNIIVAPYIALLTIASKGCKLTETMIEAFFPELYNEHSKKFKFNSQVSIIQEKLGYQSGNYHVYDFEPYYSTVALAIRDEHSSGIFNIRQESYLVSSLSEITYRFYLINLKSDLVQWSASTGAVINQMVNTVLITVYEKLQLVIENDSQFICSLAVESELPIKLLKDRNELFTKFINELKKTSSFKISKRDKDTLLKYFT
What is the function of this protein?
Acts with RNA polymerase to initiate transcription from intermediate gene promoters.
What are the official names of this protein?
Intermediate transcription factor 3 small subunit, VITF-3 32 kDa subunit, VITF-3 small subunit.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG134 family.
Protein: RT15_MOUSE
Sequence: MLRAAWRALSSVRAQAVTRAPVPALRGGSSASLLSARCGLQPPSLLRAARAYAAVQKPVQPKQDDEPPSSAFIKEYKDIIPNIEKVDDVVKRILSLEMASRKEKLKIKQEQLMNKIVENPEDSRTLEAQIIALTVRIRNYEEHMQKHRKDKAHKRHLLMSIDRRKKLLKILRQTNYDVFEKTCKELGVEYTLPPLHFQKVHRRFLAKKALCIRVYQEVQKLKKQKRALKAAAAAAKKEKNEGVPENPSNAVPEKTQVN
What are the official names of this protein?
28S ribosomal protein S15, mitochondrial, MRP-S15, S15mt.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NCPP_YERPY
Sequence: MYHVIAATTNPAKINAITLAFDDVYGPGQYRIEGVNVDSGVPLQPIGSTETRIGARQRVKNARQVRPEADFWVGIEAGIEDNMTFAWMVIEHLQARGESRSASLMLPDIILQGIRQGRELGDEMAVLSGISNVKQQGGAIGIFTQGKLTRTSVYHQALLLALVPFHNEIYQRPSPSKPAI
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: APOA1_OCTDE
Sequence: MKAVVLAVAVLFLTGSQARHFWQRDDPQTSWDRVRDFATVYVDAVKESGRDYVAQLEASLGKHLNLKLLDNWDTLSTTFSKLRSELGPVTQEFWDNLEKDTEWLRQEMNKDLVEVKEKVQPYLKNFQEKVQLELEHYRKKVEPLGTDLRDGARQKLQELQEKLTPLGEDLRDRARQHVDELRAQLGPYSDQMRQRLTQRLEALKDSASLAEYQAKAQEHLKTFSEKAKPALEDLRLGLLPVLESLKASFLSSIDEVSKKLSAQ
What is the function of this protein?
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT).  As part of the SPAP complex, activates spermatozoa motility.
What are the official names of this protein?
Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.
Protein: BRCC3_CAMFO
Sequence: MDDSSLQKVELQTDVYMVCLQHALSTENFEVMGLLIGNFACGIAKISAVIILRRLDKKKDRVEISSEQLLKAAAEAERLTVELNRPMRVLGWYHSHPHITVCPSHVDVRTQATYQTMDHSFVGLIFSVFSEGKESKEHEIFLNCFQSDNGEATEIPLEIVHTPDISDRCLRTMTDLSKILVQEEEDMAEACKDHPDVLASIHNNAVRTRALIHITDIITKPLVQTFEKRIALNKLRATHLQRQLQELQKMCNG
What is the function of this protein?
Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains, leaving the last ubiquitin chain attached to its substrates.  Catalytic subunit of the BRISC complex; does not have activity by itself, but needs to be associated into a heterotetramer with ABRAXAS2 for minimal in vitro activity (PubMed:26344097).  Plays a role in regulating the onset of apoptosis via its role in modulating 'Lys-63'-linked ubiquitination of target proteins (By similarity).  Required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating spindle assembly factors (By similarity).
What are the official names of this protein?
Lys-63-specific deubiquitinase BRCC36.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family. BRCC36 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton. Note=A minor proportion is detected in the nucleus. Translocates into the nucleus in response to DNA damage. Directly binds to microtubules and is detected at the minus end of K- fibers.
Protein: TEX30_BOVIN
Sequence: MSHTEVKLKVPFGNKLLDAVCLVPNKSLTYGVILTHGASGDMNLPHLTSLASHLASHGFFCLRFTCKGLNIVHRIKAYKSVLNYLKTSEYKLAGVFLGGRSMGSRAAASVLCHIEPDDADDFVRGLICISYPLHHPKQQHKLRDEDLFRIKDPVLFVSGSADEMCEKNLLEKVAQKMQAPHKIHWIEKANHSMAVKGRSTNDVFKEINTQILFWIQEITETDKK
What are the official names of this protein?
Testis-expressed protein 30.
Protein: NORW_SALEP
Sequence: MSRGIIIIGSGFAARQLVKNIRKQDAHVPLTLIAADSMDEYNKPDLSHVISQSQRADDLTRQLAGEFAEQFNLRLFPHTWVADIDADAHVVKSQDKQWQYDKLVLATGAAAFVPPIAGRELMLTLNSQQEYRACETQLRDAQRVLIVGGGLIGSELAMDFCRAGKTVTLMDNAASLLASLMPPEVSSRLQHHLTDMGVHLLLKSQLQKLEKTEAGIRATLVSQHSIEVDAVIAATGLRPETALARRAGVAVNRGVCVDSYLQTSHPDIYAIGDCAEINGQVLPFLQPIQLSAMYLAKNLLGGNAPLKLPAMLVKVKTPELPLHLAGETQRSDLSWQITAESDGMIAKGMSGEGQLRAFVVSEDRMKEAFALLKTLSV
What is the function of this protein?
One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase.  Reduces the rubredoxin moiety of NO reductase.
What are the official names of this protein?
Nitric oxide reductase FlRd-NAD(+) reductase, Flavorubredoxin reductase, FlRd-reductase, FlavoRb reductase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_ACIBT
Sequence: MSYFGTDGIRGKFGQMPITPEFALKLGFAAGKVLKRTSPKNKPLVVLGKDTRLSGYILESALQAGLNAAGVYVHLLGPLPTPAIAHLTRALHAHAGIVISASHNPYFDNGIKFFSSEGKKLPDSLQEEINKELEKDLFIEDTANLGKSVRVTDANGRYIEFCKSTFPYHFDLNNLKIVVDCAHGAAYSVGPSVFRELGAKVVALYNEPDGLNINENCGSTHPESLQKAVVEHGADLGIAFDGDADRVVMVDKFGNLIDGDHILYILATQAKNKPAGVVGTVMSNMALEVALEKANVGFVRAKVGDRYVLQALEENGWVTGGEPSGHILTLDKSTTGDAIIAALQVLTVMVEQNKALHELVHDFKLYPQVLVNVRLEQMLDPYSIPALVAEFNKAEEQLKGRGRILIRKSGTEPVIRVMVEGDNEQEVKTLAEHLANAVRSQAQVA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: OPGG_PSESY
Sequence: KLGVAPLTSMFLFGANQPSRVPNYRRELHDSSGLSIQAANGEWLWRPLNNPKHLSISSFSVENPRGFGLLQRGRDFSQYEDLDDRYDKRPSAWIEPKGDWGKGTVELVEIPTADETNDNIVAYWKPETLAEPGQEMAFDYRLHWTMQENSIHSPDLGWVKQTQRSIGDVRQSNLIRQPDGSLAFLVDFVGPVLAALPEDKTIRSQVTTDDNVELVENNLRYNPVTKGYRLTLRVKVKDSSKPTEMRAYLLREIPAEPGKEPALLVADKAEEKKAAAKEAAKPAVSKESANDQVEIAKADAPKPEAAKPETAKSEAGKADAAKGKGEVAKADAGKADASKAEAAKDKDGKEIQQPETEAAPTHPEPAKTLQVMTETWSYQLPSDE
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein G.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: FXD5C_XENLA
Sequence: MNLSQDSSAHHQSQDYAGVSDDEDEIDILGEDDPCSPRSHIYQQPTDSDMGDRGVLSPSKLSCNESASHSSGERERGTSKHSLDTTTNGKVKRALVKPPYSYIALITIAIMQSPHKKLTLSGICDFISSKFPYYKDKFPAWQNSIRHNLSLNDCFIKIPREPGNPGKGNYWTLDPASKDMFDNGSFLRRRKRFKRQHQELFKDGLVMYNPLHYCTPNSALQAQQIPMTCLAIPENFAMPNHLVPYPDINITVPCPDQGVHRVLTAQDVDNHPSNSHSKCSFSIENIMGETKEPEKHLTSFNQNWNYNHLLQSSRLCLLPSGSHLANAHHSAQCNLIKFPGCY
What is the function of this protein?
Transcriptional repressor.
What are the official names of this protein?
Forkhead box protein D5-C, FoxD5-C, FoxD5c, Fork head domain-related protein 12'', xFD-12'', XlFoxD5c.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEUD_MICLC
Sequence: MEKFTTHTGVGVPLRASNVDTDQIIPAVYLKRISRTGFEDALFAGWRQDPDFILNTEPFSGGTVLVAGSDFGTGSSREHAVWALKDYGFRAVISPRFADIFRGNSAKQGLVAAQVEQEDVERIWKELENRPGTTVTVDLVTRTVECGDVTAPFQIDDDTRRRLLEGLDDIAVTLGHQAEIDAYEADRPAYKPTTLPARTAG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: HUNB_EUSPL
Sequence: HLRNHFGSKPFKCDKCSYSCVNKSMLNSHLKSHSNVYQFRCSDCAYATKYCHSLKL
What is the function of this protein?
Gap class segmentation protein that controls development of head structures.
What are the official names of this protein?
Protein hunchback.
What is the protein family that this protein belongs to?
Belongs to the hunchback C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRPF_BACC3
Sequence: MKVKICGITDMETAKRACEYGADALGFVFAESKRKITPGLAKEIIQELPANVLKIGVFVNESVEVIQKITENCGLTHVQLHGGEDNHQIRRLNIPSIKSLGVTSESDMKNAQGYETDYILFDSPKEKFHGGNGKTFPWELLAHMPKELREKTILAGGLNTLNIEEAIRTVRPYMVDVSSGVETEGKKDVEKIKQFIIKAKECSK
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: SECA_ALBFT
Sequence: MATNILTKIFGSRNDRQLKQYRKSVVRINAMEAELEKLSDEALRGKTQEFKDRIAKGESLDALLPEAFAVVREGSKRVMKMRHFDVQLLGGMSLHNGKISEMGTGEGKTLTATMPVYLNALTGKGVHVVTVNDYLANRDAQWMGKLYNFLGLSVGINLPNMAREEKQAAYRADITYGTNNEYGFDYLRDNMVYEGADRVQRGLNYAIVDEVDSILIDEARTPLIISGQAEDQTDLYIAINKVVPLLQRQEGEEDIRTGEGVTKPGDFTVDEKSHQVFLTEQGHESAERILSELGLIPEGATLYDPANITLMHHLYAALRANHLYHRDQHYVVQNGEIVIVDEFTGRLMSGRRWSEGLHQAVEAKEGVAIQPENQTMASITFQNYFRLYGKLAGMTGTADTEAYEFQEIYGLETLVMPPNRPSRRDDQLDRVYKTTREKYEAAIKDIRECYERGQPVLVGTTSIENSEIIAALLDKEKLPHQVLNAKQHAREAEIIAQAGRSKVITIATNMAGRGTDIVLGGNVSKELEAVEADETLTAEQKQQQIDAIQAQWVQEHEKVKALGGLRIIATERHESRRIDNQLRGRSGRQGDPGSSRFYLSLDDSLMRIFAGDRVKAIMDRLKMPDGEAIEAGIVTRSIESAQRKVESRNFDMRKQLLEYDDVANDQRKVIYQQRNEILDAGDLSAQIASLRAGCFDDLVRQYVPVESVEEQWDIATLEKVLADDWQLNLALQQQVSAASAITDHDLLTSVQQEADRVFAAKVEQVGGENFTQFERMVLLQSIDTHWREHLSSLDYLRQGIHLRGYAQKQPKQEYKREAFELFSQLLDAVKNDVTKVLMTVKVQSSEQLEQAAEDMESRGESIANVTYMAPTETGEVETITDDETFRKKSTIPGGNVPRVGRNELCPCGSGKKYKHCHGKLA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: COX1_ORTGR
Sequence: MFVNRWLFSTNHKDIGTLYMIFGAWAGMVGTGLSILIRAELGQPGSLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAITQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMLWALGFIFLFTIGGLTGIVLSNSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFTGYTLNETWAKIHFTIMFVGVNMTFFPQHFLGLAGMPRRYSDYPDAYTTWNTISSMGSFISLTAVILMIFMIWEALASKRLVKSVPLTSTNLEWIYGCPPPFHTFEEPVFIKST
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: EF1A1_MOUSE
Sequence: MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKKIGYNPDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGSASGTTLLEALDCILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPVLDCHTAHIACKFAELKEKIDRRSGKKLEDGPKFLKSGDAAIVDMVPGKPMCVESFSDYPPLGRFAVRDMRQTVAVGVIKAVDKKAAGAGKVTKSAQKAQKAK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.  Plays a role in the positive regulation of IFNG transcription in T-helper 1 cells as part of an IFNG promoter-binding complex with TXK and PARP1.
What are the official names of this protein?
Elongation factor 1-alpha 1, EF-1-alpha-1, Elongation factor Tu, EF-Tu, Eukaryotic elongation factor 1 A-1, eEF1A-1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, nucleolus. Cell membrane. Note=Colocalizes with DLC1 at actin- rich regions in the cell periphery. Translocates together with ZPR1 from the cytoplasm to the nucleus and nucleolus after treatment with mitogens. Localization at the cell membrane depends on EEF1A1 phosphorylation status and the presence of PPP1R16B.
Protein: SELA_MANSM
Sequence: MTALFQQLPSVDKILKTPQGEQLVTEFGHSAVVNCCRHLLAQAREKIKIEKKLPHFFTDFNHTIAEVNRYLANQQQVKIKSVHNLTGTVLHTNLGRALWAQSAQQAALTAMRQNVALEYDLEAGKRSHRDNYVSELLHELTGAQAACVVNNNAAAVLLMLATFAQGKEVIISRGELIEIGGAFRIPDIMAQAGCKLVEVGTTNRTHLNDYRRAINENTALLMKVHSSNYQICGFTCEVSEQELVELGKEFNIPVVTDLGSGALTDLSRYDLPKEPTVQEKLVQGADLISFSGDKLLGGPQAGIIVGKKELIQQLQSHPLKRVLRCDKVILAAMEATLRLYLQPEKLTEKLTSLRLLTQPLEQLRQQAEQLKAKLENLLKDDFLLQIESSLAQIGSGSQPMAKIPSIAVTIAEKNSEKLTALLARFKKLSTPIIARVENDKIRLDLRSVTAIETLLITLEELNQDQ
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.