PharMolix/UniProtQA huggingface dataset:
Protein: FBX10_MOUSE
Sequence: METGGLPLELWRMILAYLHLPDLGRCSLVCRAWYELILSLDSTRWRQLCLGCTECRHPNWPNQPDVEPESWREAFKQHYLASKTWTKNALDLESSICFSLFRRKKERRTLSVGPGHEFDSLGSALAMASLYDRIVLFPGVYEEQGEIILKVPVEIVGQGKLGEVALLASIDQHCSTTRVCNLVFMPAWFSPIMYKTTSGHIQFDNCNFENGHIQVHGPGTCQVKFCTFKNTHVFLHNVPLCMLENCEFVGSENNCVTVEGHPSADKNWAYKYLLGLIKSSPIFLPAEDHDFLMSLDLESRDQAWSPRTCDIVIEGSQSPTSPVCSSPKPGSKEAEVGSDGERVAQTPDSSDGGLSPSGEDEDDEQLTYRLSYQVQGPRPVLGGSFLGPPLPGASIQLPSCLVLNSLHQELQKDKEAMALASSVQGCLIRKCLFRDGKGGVFVCSYGRAKMEGNVFRNLTYAVRCIHNSKIVMLRNDIYRCRASGIFLRLEGGGLIAGNNIYHNAEAGVDIRKKSNPLILCNQIHHGLRSGIVVLGNGKGVIRNNQIFSNKEAGIYILYHGNPIVSGNHIFKGRAAGIAVNENGKGLITENVIRENQWGGVDIRRGGVPILRSNLICFGYSDGVVVGDEGKGLIEGNTIYANKGCGVWMMSSSLPHVTSNHVSYNGLYGVAVFSQKDGEFPGGHGAQENFSEDGDAILWEAELEKEDDPLRRPITVALVESNSINHNGASGIFVQSSEALQVVANVIHANGDRGITIVQSSQLTRVANNSISCNRQSGVKVEFQCKVELRGNGIYDNRGHGIITKGDGTAVVENDIIGNRGSGLQLLPRSDTKVLKNRIHSFRAYGIAVRGRVKALVQENIIFQGKTNKTIFQQITNNRECIMQNNKFLVFKKKSDTWRLVNPPARPHLENSLRGSSAAHSGHKVTAMATRITARVEGGYHSNRSIFCTIL
What is the function of this protein?
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.  Mediates the ubiquitination and degradation of BCL2, an antiapoptotic protein, thereby playing a role in apoptosis by controlling the stability of BCL2.  Targets also the receptor for advanced glycation end products RAGE for ubiquitination and subsequent lysosomal degradation.  Directly controls HGAL/GCSAM ubiquitination and degradation and thereby decreases BCR signaling.
What are the official names of this protein?
F-box only protein 10.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPC_SALEP
Sequence: MIGLRPAFSTMLFLLLLTGGVYPLLTTALGQWWFPWQANGSLIHKDNVIRGSALIGQSFTAAGYFHGRPSATADTPYNPLASGGSNLAASNPELDAQIQSRVAALRAANPQASSAVPVELATASASGLDNNLTPGAAAWQIPRVAAARQLPVEQVAQLVAEYTHRPLARFLGQPVVNIVELNLALDALQGHRAK
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: NADK_LACP3
Sequence: MRVTVFHNSIPASITAAQKLTKLLKSGHFELDERHPEVVVTIGGDGTLLSAFHRYADQLNSIRFIGVHTGHLGFYTDWRDFEIEDLVIALKEDSGQSVSYPLLDVQATYADATSAHYLALNESTLKRLNGTMRTEVYIKGDFFESFRGDGLCVSTPTGSTAYSKSNGGAVIHPRLDALQMTEIASINNRVFRTLSSPIITAPDEWVTLEPTGRDDYVMTVDQFVINPPTIKQIRYKIAKERIHFARYRHMHFWDRVEDAFIGAKH
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_STAAU
Sequence: MLNNKRLFTSESVTEGHPDKIADQVSDAILDAILKDDPNARVACETTVTTGMALIAGEISTTTYVDIPKVVRETIKEIGYTRAKYGYDYETMAILTAIDEQSPDIAQGVDKALEYRDKDSEEEIEATGAGDQGLMFGYATNETETYMPLAIYLSHQLAKRLSDVRKDGTLNYLRPDGKVQVTVEYDENDNPVRIDTIVVSTQHAEDVTLEQIQEDIKAHVIYPTVPENLINEQTKFYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGIARHGGGCFSGKDPTKVDRSAAYAARYVAKNIVAAGLADQCEVQLAYAIGVAEPVSIAIDTFGTGKVSEGQLVEAVRKHFDLRPAGIIKMLDLKQPIYKQTAAYGHFGRTDVLFPWEKLDKVEELKDAVK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BTN1_USTMA
Sequence: MVTIEALPLRPIEGEQQALHVGAHSSASDPRRTMVTNTSESPLASRQATLTTSTRQKHTSYRLNTAFFLFGLLNNSLYVVILTAALELLPQGVPTGLVSFANIFPALIAKAIWPYFLRGQVRYSKRVWSCAALSFIGMLLVSFFPALAMRLVGISLASFSSGLGELTFLQLSTRYAPKSSETRSGLTAAQAAGAGLETSFAGDAVGWFASGTGAAGLIGAAAWWVVRPLGVQTGMAILSVLPAFMIMAYAIILPSVQELLEGKDGKGGAMYAPLSTEDDAVERSSSDDQPTTANDDRQDSTIHIGPGSEQDVKVRLSFQEKMALLKPMLQPYIIPLVIVYAMEYTINQGIAPTLIYPLPTRSSHPLLSHIIRKLTDYYPLYQLVYQTFVFLSRSSISIFKLPAIPRHLLWLPAVLQTGLLAVLLTESLYAWFRESIASPLVIVLICVEGLAGGSAYVSVFYSIGVDEQGRGIALPSTGEEVDDEGQEEDSAYTMAKKAQEHEFRIGCVGFGDSLGILAASLISMPLQVSLCDAQVRSGRDLCKQT
What is the function of this protein?
Involved in vacuolar transport and vacuole pH homeostasis.  Also required for cytokinesis (By similarity).
What are the official names of this protein?
Protein BTN1.
What is the protein family that this protein belongs to?
Belongs to the battenin family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: GST28_SCHBO
Sequence: MTGDHIKVIYFNGRGRAESIRMTLVAAGVNYEDERISFQDWPKIKPTIPGGRLPAVKITDNHGHVKWMVESLAIARYMAKKHHMMGGTEEEYYNVEKLIGQAEDLEHEYYKTLMKPEEEKQKIIKEILNGKVPVLLDIICESLKASTGKLAVGDKVTLADLVLIAVIDHVTDLDKEFLTGKYPEIHKHRENLLASSPRLAKYLSDRAATPF
What is the function of this protein?
GST isoenzymes appear to play a central role in the parasite detoxification system.  Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut.
What are the official names of this protein?
Glutathione S-transferase class-mu 28 kDa isozyme, GST 28, Sb28GST.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Mu family.
Protein: YCDX_ESCF3
Sequence: MYPVDLHMHTVASTHAYSTLSDYIAQAKRKGIKLFSITDHGPDMADAPHHWHFINMRIWPRIVDGVGILRGIEANIKNTEGEIDCFGQMYDSLDLIIAGFHEPVFAPHDKATNTQAMIATIASGNVHIISHPGNPKYPIDIMAVAEAAAKHQVALEINNSSFIHSRKGSEDNCRAVAAAVRDAGGWIALGSDSHTAYTLGEFDEALKIIEAVDFPEDRILNVSPARMLGFLESRGMTPIAEFAEL
What are the official names of this protein?
Probable phosphatase YcdX.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: S19A1_MOUSE
Sequence: MVPTGQVAEKQAYEEPRQDHELKSWRCLVFYLCFFGFMAQLRPGESFITPFLLERKFTKEQVTNEIIPMLPYSHLAVLVPVFLLTDYLRYKPVLVLQCLSFVCVWLLLLLGTSVVHMQLMEVFYSVTMAARIAYSSYIFSLVHPSRYQRMASYSRAAVLLGVFISSVLGQALVTVGHISTYTLNCVSLGFILFSLVLSLFLKRPKRSLFFNRSTLARGALPCELDQMHPGPDRPETRKLDRMLGTCRDSFLVRMLSELVENARQPQLRLWCLWWVFNSSGYYLITYYVHVLWRSTDSSLSYNGAVDAASTLLSAITSFSAGFLSIRWTLWSKLVIAGVIAIQASLVFCMFQIRDIWVCYVTFVLFRGAYQFLVPIATFQIASSLSKELCALVFGINTFLATALKTCITLVVSDKRGLGLQVRDQFRIYFIYFLMLSITCFAWAGLDGLRYCQRGRHQPLAQAQELRSPLETSVQAISLQDGDLRGPQPSAPQLLSEDGMEDDRGDLRVEAKA
What is the function of this protein?
Antiporter that mediates the import of reduced folates (PubMed:8276792, PubMed:8664315, PubMed:9111015, PubMed:9748272).  Mechanistically, acts as a secondary active transporter, which exports intracellular organic anions down their concentration gradients to facilitate the uptake of its substrates (By similarity).  Has high affinity for N5-methyltetrahydrofolate, the predominant circulating form of folate (PubMed:8276792, PubMed:9111015).  Also able to mediate the import of antifolate drug methotrexate (PubMed:8276792, PubMed:8664315, PubMed:9748272).  5-amino-4-imidazolecarboxamide riboside (AICAR), when phosphorylated to AICAR monophosphate, can serve as an organic anion for antiporter activity (By similarity).
What are the official names of this protein?
Reduced folate transporter, Intestinal folate carrier 1, IFC-1, Plasma membrane folate antiporter SLC19A1, Reduced folate carrier 1, RFC-1, RFC1, Solute carrier family 19 member 1.
What is the protein family that this protein belongs to?
Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.
Protein: ANMK_ECO81
Sequence: MKSGRFIGVMSGTSLDGVDVVLATIDEHRVAQLASLSWPIPVSLKQAVLDICQGQQLTLSQFGQLDTQLGRLFADAVNALLKEQNLQARDIVAIGCHGQTVWHEPTGVAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHPTERRMVLNIGGIANLSLLIPGQPVGGYDTGPGNMLMDAWIWRQAGKPYDKDAEWARAGKVILPLLQNMLCDPYFSQPAPKSTGREYFNYGWLERHLRHFPGVDPRDVQATLAELTAVTISEQVLLSGGCERLMVCGGGSRNPLLMARLAALLPGTEVTTTDAVGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGASQETVLGAIFPANP
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: RL2_ASHGO
Sequence: MGRVIRNQRKGAGSIFTSHTRLRQGAAKLRTLDYAERHGYIRGVVKQIVHDAGRGAPLAKVVFRDPYKYKLREETFIANEGVHTGQFIYAGKNASLNVGNILPLGSVPEGTIVSNVEERPGDRGALARTSGNYVIVIGHNPDENKTRIRLPSGAKKIVSSDARGVIGVIAGGGRVDKPLLKAGRAFHKYKVKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVSGQKAGLIAARRTGLLRGSQKTQD
What are the official names of this protein?
60S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: Y1261_METTH
Sequence: MKHKGAILIVIGVVALAAMILIIGPGEIEDALRKADPVYVLMAVVLEFIILALFTLRWSITTRAVSIDVGKRHLFPMLLVGMAINNLTPSARGGGEPVRAYMLGKYSRASMESAFATVIADRGLDTFPFIFLAVLTIIGIVLYFDLSRWILAALIASVVIIVVAFFLALYVSVDRDAGERITGWILGVVKRFYRKNHERLERRVRSALHEFQSTMRMMLKEKNVLVYGIPISFLIWILEIIRVYLIFTAFGTDISLLVIAEVFILATLIGMIPLLPGGLGAVDGIMIVFYSYAGVSPSVSAAATVVERLISFWMISAMGVAAIPYFGSSVSEKLMDKL
What are the official names of this protein?
UPF0104 membrane protein MTH_1261.
What is the protein family that this protein belongs to?
Belongs to the UPF0104 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TMEDA_GIBZE
Sequence: MAPQKSLLQYICSFLLLVSSVSALKFDLIAGSKERCVRNFVGKDTLVVVTATVDGYKGDGMVVNLYIRDAVGNEYGRPRDVVGESRTVFTSHADAAFDVCFENVPSGSQRLNSPTRHIELDIDIGADAKDWSAIQATEKLKPVEAELRRVEEITSELVTEMEYLRAREQKLRDTNESTNNRVKWFGIATTWLLVGLWAWQIMYLRAYFRSKHLI
What is the function of this protein?
Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles.  Required for efficient transport of a subset of secretory proteins to the Golgi.  Facilitates retrograde transport from the Golgi to the endoplasmic reticulum (By similarity).
What are the official names of this protein?
Endoplasmic reticulum vesicle protein 25.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=Recycles between endoplasmic reticulum and Golgi.
Protein: AATPC_ARATH
Sequence: MSSSSESHLATAKTALTAVASVAAAAILARSVVQDYMPNEVHEYISHGFRRFFSYFSYQMTAVIEEFGGFEHNQVFEAAEAYLSTKISNSTRRIKVNKLEKQSNYSVTVERDEEVVDIFDGVKLSWILVCRHVDKKDFRNPRDLNSTLKSEVRSYELSFRKKFKNMVLESYLPFVVEQAASIKQKFKTLKIFTVDSYSVEWTSVTLDHPSTFRTLALDPEVKKNLVEDLDRFVQRKGFYGRVGKAWKRGYLLYGPPGTGKSSLIAAIANHLNFDIYDLDLTSLNNNAELRRLLMSTANRSILVVEDIDCSIELKDRSTDQENNDPLHKTVTLSGLLNFVDGLWSSCGNERIIVFTTNYREKLDPALLRPGRMDMHIHMSYCTPAAFKVLASNYLEIQDHILFEQIEEFIREIEVTPAEVAEQLMRSDSVDKVLQGLVEFLKAKKQIDNSKA
What are the official names of this protein?
AAA-ATPase At3g50940.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. BCS1 subfamily.
Protein: PYRB_PHOLL
Sequence: MANPLYRKHIISINDLSREDLELVLQTAATLKARPQPELLKPKVIASCFFEASTRTRLSFETAIHRLGASVVGFSDSSNTSLGKKGETLADTISVISQYVDAIVIRHPQEGAPRLASEFSGDTPIINAGDGANQHPTQTLLDLFTIQETQQRLDSLNIAMVGDLKYGRTVHSLSQALAKFNGNHFYFIAPEALAMPNHILHMLNEKGATYSQHANIEEVLPELDILYMTRVQKERLDPSEYANVKAQFVLRASDLIGAKENLKVLHPLPRIDEITADVDKTPYAYYFQQAENGIYARQALLSLVLNE
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: SEC11_ARTOC
Sequence: MFAELAPYLSNPRQTLAQILNFALVLSTAFMGWKALSVYTNSPSPIVVVLSGSMEPAFQRGDLLFLWNNSPRAEVGEIVVYNVQGKDIPIVHRVIKAFGAGDGGNKSQRRLEREADKPSGPGLSSPLSHQILTKGDNNIADDTELYAQGQDYLDRKLDIVGSVRGYIPAVGYVTIMLAENPWMKTVLLGIMGVMVMLQRE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: NO40_SESRO
Sequence: MKLCWQKSIHGS
What is the function of this protein?
Modulates the action of auxin, and may function as plant growth regulator that alters phytohormone responses.
What are the official names of this protein?
Early nodulin-40.
Protein: PRRX2_HUMAN
Sequence: MDSAAAAFALDKPALGPGPPPPPPALGPGDCAQARKNFSVSHLLDLEEVAAAGRLAARPGARAEAREGAAREPSGGSSGSEAAPQDGECPSPGRGSAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLASRSASLLKSYSQEAAIEQPVAPRPTALSPDYLSWTASSPYSTVPPYSPGSSGPATPGVNMANSIASLRLKAKEFSLHHSQVPTVN
What is the function of this protein?
May play a role in the scarless healing of cutaneous wounds during the first two trimesters of development.
What are the official names of this protein?
Paired mesoderm homeobox protein 2, Paired-related homeobox protein 2, PRX-2.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS6_YARLI
Sequence: MKLNIAYPAQGTQKCIDIEDEHRVRGFYEKRMGQEVEADFLGDEFKGYVLKITGGNDKQGFPMKQGVMHPTRVRLLLSKDSSCYRSRRAGERKRKSVRGCIVSSDLSVLSVVIVKQGDADIEGLTTETVPRRLGPKRANNIRKLFALSKEDDVRQYVIRREVTTKSGKTYTKAPKIQRLITPRRLAHKAQLREKKVKAIQASKDAAAEYAQLLAKRVAEKKSEKAEEKKRRASSLRTQSVQA
What are the official names of this protein?
40S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS6 family.
Protein: RECF_CHLT3
Sequence: MKLFKLSIHGFRSHQDAVFLPHDGINLIYGKNGTGKTNLLEAIHYTCLTKSFLSTSDSDALHFQAGHFELEAVLQSDSENESKVRVYYSPAEGKHVFINKTPLESFSKIVGEFPCVALSPYDIALTQGSPQERRRFLDASISQTNKAYLADLLSYRRVLAQRNKLLADMKHRTFSSPELDVWTASLSALAASIIFRRIHFVRDFAQYLENAYADFQSIDETPGLTYKTELSLNENSFSEAELAKQISEKFEEMKFDELRRGLTLFGPHRDDLAFSINNLSLRKYASQGQHKTFVICLKLAQYFYICELLSEKPIFLLDDVFSELDSQRAEELVRILSSKRSGQSFITTTERKDFAEVKQHTIGGIISG
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AQP3_MILTA
Sequence: MAISWRTWLKKTIHCDNSYVRTGLAEFLGTFLLVLLLNGMIITAHMSVRNADGTMAHPLNTAHLAFGGGLAVMVAVLVSGGISGAHLNPAVTTTMLVMGRLSPLKSLVYIFMQYMGAFFAASILYAVYFESILAYDYGERQVLGANGTAGWFATYPQEHISLVTQIFDAILGTGLLVMGIFAIIDPNNMAVPKGQIPLYVGFLISSLIFSFSYNAGAALNPARDLAPRLFLWVIGYGAEAFTARGHLWWLVPVIGPHVGGLLGGVTYQMFIGAHYQSDRKLKPATIMDEDDDTNATYNTITTTTHQKVYNGRRNFDESVPLKTVHA
What is the function of this protein?
Aquaglyceroporin that may modulate the water content and osmolytes during anhydrobiosis (PubMed:23761966).
What are the official names of this protein?
Aquaporin-3, AQP-3.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPA_BACMK
Sequence: MSIRAEEISALIKQQIENYQSEIEVSDVGTVIQVGDGIARAHGLDNVMAGELVEFSNGVMGLAQNLEENNVGIIILGPYTEIREGDEVRRTGRIMQVPVGKELIGRVVNPLGQPVDGLGPINTTNTRPIESPAPGVMDRKSVHEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTAVALDTIINQKDEDMICIYVAIGQKESTVRNVVETLRKHGALDYTIVVTASASQPAPLLYLAPYAGVTMGEEFMYNGKHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDARGGGSLTALPFIETQAGDVSAYIPTNVISITDGQIFLQSDLFFSGVRPAIDAGTSVSRVGGSAQIKAMSKVSGTLRLDLASYRELEAFAQFGSDLDKATQAKLNRGARTVEVLKQGLHKPLRVEKQVIILYALTRGFLDDIPVVDITRFEEEFHAWLDSNATDLLSEIRTTKKLADDDKFAAAINGFKKVFVASE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS15_YERPB
Sequence: MSLSVEAKAKIVADFGRGTNDTGSSEVQVALLTAQINHLQGHFSEHKKDHHSRRGLLRMVSTRRKLLDYLKRQDVARYASLIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: HEM3_BURCM
Sequence: MNSETISAQAPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRTLSKVGGKGLFVKELENALADGRADLAVHSLKDVPMALPDGFALTAIMEREDPRDAFVSNDYASLDALPAGAVVGTSSLRREAMLRARYPHLDVLPLRGNLDTRLAKLDRGDYAAIILAAAGLKRLGLEARIRTLIDVEDSPPAAGQGALGIEIATHRTDVAAWLAPLHDPRTALAVEAERMVSRALGGSCEVPLAAHAVWRAGELYLTGRVSTTDGQRVLTAEECGAVMTVADALALGRAVSDELEAQGALDIVNALLAASQAGKGDA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: NU5C_CICIN
Sequence: MEQTYQYAWIIPFLPLPVPMLIGLGLLLFPTATKSLRRMWAFQSVFLLSIVMILSMNLSIQQINSSSVYQYVWSWIINNDFSLEFGYLIDPLTSIMSILITTVGIMVLIYSDNYMSHDHGYLRFFAYMSFFSTSMLGLVTSSNLIQIYIFWELVGVCSYLLIGFWFTRPVAAKACQKAFVTNRVGDFGLLLGILGFYWITGSFEFSDLFQIFNNLISNNEVNFLFVTLCAILLFAGAIAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLMPLFIVIPHIMNFISLIGIITVFLGATLALAQKDIKRGLAYSTMSQLGYMMLALGMGSYRSALFHLITHAYSKALLFLGSGSVIHSMETLVGYCPKKSQNMVLMGGLTKHVPITKNSFLLGTLSLCGIPPLACFWSKDEILNDSWLYSPIFGIIAWSTAGLTAFYMCRIYLLTFEGHLNVHFQNYSGKSNTPFYSISLWGKEGSKISNKNFRLLTLLKMNKNARPSFFSNRVYKIDENVRNRIQPFLSIPHFGNTKTYSYPYESDNTMLFPILVLILFTLFVGFLGIPFTQDVDILSKWLTPSINLLHKNSNNLIDWYEFSKDAFFSVSIASFGIFIAFFLYKPVYSTFQNLDFLNAFVKMGPNRIFYDKIKNAIYDWSYNRGYIDAFYGRFLTAGMRKLADFAHFFDRRIIDAIPNGVGLMSFFLAEVIKSVGGGRISSYLFFYFSYVAIFLLIYYFFNL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: YOBH_BACSU
Sequence: MAKAIQSSMWREFGLMCTVGIGDNMLLSKLALDLESKKTKSGIARWRYEDVPNRLWKVRPLSKMWGIGGRMERNLNRMGISTVGQLAKFPLELLEKKFGIMGNQLYYHAHGIDLSEIGAPLMQGQISFGKSQILFRDYTKREEIKAVLLEICEEVARRARTYNKVGRTISLGIGYSKDELGGGFHRSKTIDFPTNITMDIYKCCLMFFNKFYSGKKQ
What are the official names of this protein?
DNA repair protein homolog YobH.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
Protein: CT144_HUMAN
Sequence: MGNYSSHKRTKAPKQARKERPADMDKAWWKSFLNHLTRKKPATRIVLILPLDKRQPLANAGQRIDYASGAGLGSPAAPRLRGAGEGSEREPRMPVLLLLRRQEARRPEEGGARAALSWPRLLSRFRSPGKAPREAGPAEEQPRKRCRCPRPQL
What are the official names of this protein?
Uncharacterized protein C20orf144, Bcl-2-like protein from testis, Bclt.
Protein: GLNB_HAEIN
Sequence: MKKIEAMIKPFKLDDVRESLSDIGISGMTITEVRGFGRQKGHTELYRGAEYMVDFLPKVKLEVVVPDELVDQCIEAIIETAQTGKIGDGKIFVYHVERAIRIRTGEENEDAI
What is the function of this protein?
P-II indirectly controls the transcription of the glutamine synthetase gene (GlnA).  P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of GlnA.  When P-II is uridylylated to P-II-UMP, these events are reversed.  When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylation of glutamine synthetase by GlnE, so activating the enzyme (By similarity).
What are the official names of this protein?
Nitrogen regulatory protein P-II.
What is the protein family that this protein belongs to?
Belongs to the P(II) protein family.
Protein: RS13_ACIBY
Sequence: MARIAGVNIPDNKHAVISLTYIFGIGRHTAKNILAAVGITETTKIRELDDAQLDAIRAEVAKVPTEGDLRREISMNIKRLMDLGCYRGLRHRRSLPVRGQRTKTNARTRKGPRKPIKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: ATPD_THENN
Sequence: MKLSAVAGRYARAFLNIAIENEKEDEYLRFLDFVCNVYESNKDLFDNPVVKPEKKVTLIKSVLEEFGEEMDEFQERFLMLLFERKRQKLLRNIHELFEYEKILSEQKVPADLRIAHVPKEEELTLLRKFIRKYALKDPVFKTTVDESLIAGAVVEFEGFRLDTTVQGRLKRLSQETLKRGEMS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.