PharMolix/UniProtQA huggingface dataset:
Protein: NRAM5_ARATH
Sequence: MTGSTVSRQENSPKRPNDSNGEFKRLLVPETSQPEEDELHESPPENQILNVEEDRDKTYDSVPPFSWAKLWKFTGPGFLMSIAFLDPGNIEGDLQAGAVAGYSLLWLLLWATLMGLLMQLLSARIGVATGRHLAEICRSEYPSWARILLWFMAEVALIGADIQEVIGSAIALQILTRGFLPIWVGVIITSFDCFLISYLEKCGMRKLEGLFAVLIATMALSFAWMFNETKPSVEELFIGIIIPKLGSKTIREAVGVVGCVITPHNVFLHSALVQSRKTDPKEINRVQEALNYYTIESSAALFVSFMINLFVTAVFAKGFYGTKQADSIGLVNAGYYLQEKYGGGVFPILYIWGIGLLAAGQSSTITGTYAGQFIMEGFLDLQMEQWLSAFITRSFAIVPTMFVAIMFNTSEGSLDVLNEWLNILQSMQIPFAVIPLLTMVSNEHIMGVFKIGPSLEKLAWTVAVFVMMINGYLLLDFFMAEVEGFLVGFLVFGGVVGYISFIIYLVSYRSSQSSSWSSLEMSERVVSTET
What is the function of this protein?
Seems to be involved in iron uptake.
What are the official names of this protein?
Metal transporter Nramp5, AtNramp5.
What is the protein family that this protein belongs to?
Belongs to the NRAMP (TC 2.A.55) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ATP25_TALSN
Sequence: MAAAALIRSTRCNTCRRYLLQSFTRVVGLTAQNSRLPNEPQRRQFFTTPYLNIKSSHRHLSDRDASAASNNEYFITNESANSSQAVPWYLQVEPVIEPTHPAVRQQEIPAVPANAPPITQEILQHLSLEIGLDDMVLLDLRGRDPPPALGGNVIMVIGTARSLKHLNVSADRFCRWLRSTYKLRPYADGLLGRNELKIKLRRKARRARLASSSGTISDTSDDGITTGWICVNVGSVDDPSVVQNMREGGFEGFGKVQGGTRIVVQMFTEDKRADVDLEQLWAPKDNVKAGDSEENHSYSTGGDYQVRSMPPITSENNSNHPISNVPRPLRRVDLSQRRSFSTGAGQHSARTDVDPESGYEVVDAKNESSRQEPPLSAIFSTLKEMSPEETIEQLGSGPEDKNSTEFLRDCYSSVGTSHNGNSALRLMLGAAGVSAQHPGYTKEYLWTLFLEQTASGYRISEPLGFEIASAFLVPRRLDAKEQGRTASEFVDFDIESAMRVMDNLSLNGETIIRKHRVYNMMYEALILGLRNERLDDVRLKALRIRTLMTEIGLDWQSEDTRETMQLRLLLGDVDGFYEIWHAIAFNEGSRTADDYELLFRVHAEAGNPVYARECLGVWISMMGREDPPVLPSASIISAIARCAHVAGHDADTFRLLSASDEWREVERLILSDLRTLEQLT
What is the function of this protein?
Probable mitochondrial mRNA stabilization factor.
What are the official names of this protein?
ATPase synthesis protein 25, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATP25 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RL17_ENDTX
Sequence: MIKTYNGSKLGIASSHRKALLRNLAAALFLYEKITTTLSKAKELVSYSEKLVTKAKKADLSAMRAINGEINSKAAVKKIFDILVPRYKERSGGYTQILKVGTRRGDSADVAIVKLVT
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: YABA_LACPL
Sequence: MDKRDLYDSFGEMEQQMQQMLDKMAKLRADMTTVLEKNAELVIENEHLREHMVEIENELPKKAASTTTLSKSRQNLEKLYDEGFHVCNQFYGKRRDDDESCVFCLEVIYGERERA
What is the function of this protein?
Involved in initiation control of chromosome replication.
What are the official names of this protein?
Initiation-control protein YabA.
What is the protein family that this protein belongs to?
Belongs to the YabA family.
Protein: AROK_GEOSL
Sequence: MRGTWSMSVPSDGRNVVLTGFMGTGKSTVGKLLARRLGYRFSDLDALIVERAGISINEIFERYGEQRFRELETEAIRSLGGVSGRVVATGGGAVIAPRNRVLLREAGLVVNLTASLEVILSRLKGDRERPLLKSNNTPEALAALMTARENAYADADLRIDTAGKSVEDVVTEIATFVREHQ
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TU179_LOPOL
Sequence: MMAKQVVVLLALLLLLPIVTASMGDASGRTGRIYMYGTSIQDLFRYLQLDYQRNVFLLRFLLGRGGLLLH
What is the function of this protein?
Acts as a neurotoxin by inhibiting an ion channel.
What are the official names of this protein?
Turripeptide OL179.
What are the subcellular locations of this protein?
Secreted.
Protein: GATB_RHIL3
Sequence: MTLVDVRTPDPKRFIPGATGDWEVIVGMEVHAQVLSNSKLFSGASTEFGKPQNSNVSMVDAAMPGMLPVINEECVKQAVRTGLGLKAQINKRSLFDRKNYFYPDLPQGYQISQFKDPIVGEGKIVISLGPDRQGQFEDIEIGIERLHLEQDAGKSMHDQHATMSYVDLNRSGVALMEIVSKPDMRSSDEAKAYMTKLRSIVRYLGTCDGNMDEGSMRADVNVSVRRPGEDFGTRCEIKNVNSIRFIGQAIEYEARRQIGILEDGGKIDQETRLFDPNKGETRSMRSKEDAHDYRYFPDPDLLPLEFDDAFIKALEADLPELPDDKKERFVRELGLSIYDASVLVSEKAIADYFEAVAAGRDGKTAANWVINDLLGALNRTGKDIEQTPVSPAQLGAIIDLIKAGTISGKIAKDLFEIVLAEGGDPAEIVEARGMKQVTDTGAIEKAVDEIIAANPDQVEKVKAKPTMAAWFVGQVMKATGGKANPQAVQALVKAKLGIEE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: COMA2_BACSU
Sequence: MDMKHTLLEALGIEIVENTAERCVAVMPVDHRTVQPFGYLHGGASVALAETAASAGAQNLIDHTTQACVGLEINANHLKSVKEGTVKAIAEPVHIGRTTIVYHIHIYDEQERLICISRCTLAVIKK
What is the function of this protein?
Is not required for competence.
What are the official names of this protein?
Putative esterase ComA2, ComA operon protein 2.
What is the protein family that this protein belongs to?
Belongs to the thioesterase PaaI family.
Protein: THIE_SALAI
Sequence: MSSLGRLHLITDNRPGQDPLAVVRAALSVARAELVVQVRVTDETTDRQAYDLARRVTVLCARYGATCLVNDRLHVALAVGADGGHVGADDLPVGAARAVLGSAAVLGATAREADTAVEAVAAGASYLGVGSVHPTTSKDGLPPPIGAAGLRAVAAAVSVPVIAIGGVTAADVPDLRAAGAYGVAVIAALSHAADPARATAAFVEALTC
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: MSXC_DANRE
Sequence: MAPLSSMMNSLQGPLSQEGKLQERKSDKEDAQSNDKAAVKGCKGKALSLPFSVESLISDRTSSRTLYTSSEAGIISPTSGADERLKLSPMALYADRKIPVESVSNLSDCKRGDMEELSDKGQSGWFQTTSYTSPPRHSSPPPCTLRKHKNNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSNSLNLTETQVKIWFQNRRAKAKRLQEAELEKLKLATKPLLPAFAFPFPLGTHVGSPPLYGPSSSFPRPALPVPGLFGGPVTYGMYYLS
What is the function of this protein?
Involved in the development of the inner ear.
What are the official names of this protein?
Homeobox protein MSH-C.
What is the protein family that this protein belongs to?
Belongs to the Msh homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y226_MYCGE
Sequence: MQTNKQPKQQFSEKQFIAFVFNYIAGFGFISVVMTMFDVGPFSYLVLGLTSFAILGVVLSFSRLSVLCGNSAYGGSYLIAKKAVGTNSKTKRFFVFLSGWNVSLTGSFNGVVIPAVLIFSFADIPVVKANNNIIIGLLVGGFLLFGLLTFISLFGLKINKKAIFYFAVIKWIVVIGGFILGIYLIGTTNGKGFVENNLIGTRENIDFFKIIFISLALTIAFAGTEDLASITPDVKSNNLRKCFLIAFGCVVLLYLVGFVIISGLDGIRGYGLALGNKDPKAINNYGSIYRLVGGVPLLVIYGLGLLVNSLASRLSMTITTARKYVALAQDGFLPSFLAKTNKHNEYHHAVLISNLMTLLVMLIMVIIPFLPDHNNNNNSLFNAIEQLVTVTIEMAAAISLIQYFITFIFFFMIFAKKENQKLIPLWEKVSYVISFALVSVLLFVPLFPFNQWTVFNTFKIVVLICFYLLGVGFFGYAEWKNKNKYQLMNNNS
What are the official names of this protein?
Uncharacterized protein MG226.
What is the protein family that this protein belongs to?
To M.genitalium MG225.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HRCA_STAA2
Sequence: MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRNEMKQLEDLNYIEKTHSSSGRSPSQLGFRYYVNRLLEQTSHQKTNKLRRLNQLLVENQYDVSSALTYFADELSNISQYTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVEHVHLASDIPFSNDKLNTISNFVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLINTMNNHISNQSNSIYMGGKVKLIDALNESNVSSIQPILQYIESNRIAELLQDISSPNINVKIGNEIDDSLSDISIVTSQYHFDETLKGQIAVIGPTAMHYQNVIQLLNRIW
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: UPP_RHOCS
Sequence: MRTHPDFPNLFILDHPLIQHKLSHMRDRQRSTMGFRQLLKEIALLMGYEITRDLPLTTEAIETPLCTMDAPVIEGKKLAIVPILRAGLIMAEGLLELVPAAREGHIGLYRDHDTKMPVEYLVKLPDPAGRRFILVDPMLATGNSAVHAVDVLNRNGVLDAQIRFMALVAAPEGVRTFHAAHPTVPVFTAGLDSHLNPNAYIVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: CPVL_RAT
Sequence: MVRAQWKVIILLILLMVIPSDGLFHSIYRSILVAQPFKGNAGQPLFLSPYIRTGKIKEGQRKSMVSPFPGMYDKSYAGYITVNQTYNSNLFFWFFPARTQPADAPVVLWLQGGPGGSSMFGLFVEHGPYIITSNMTVLSRDFPWTFSLSMLYIDNPVGTGFSFTDHIQGYAIDEDDVAQDLYSALVQFFKLFPEYAKNDFYITGESYAGKYVPAIAYYIHSLNPVRRFKIRLKGIALGDAYTDPETIIGGYATFLYEVGLLDEQQRRHFRKQCRKCIKYIKEQEWMKAFEVLDELLDGDLTAGPSFFQNVTGCTNYYNILQCTEPEDQSYFSKFLSLPQVRQAIHVGNRNFSDGAEVEKYLREDTVKSVKPWLAEIMNYYKVLIYNGQLDIIVAAALTERSLMTMDWKGSYAYRRTHKKIWKIFESDDEVAGYVRRVGKFHQVIVRGGGHILPYDQPLRSFDMINRFIYDRGWEPYKL
What is the function of this protein?
May be involved in the digestion of phagocytosed particles in the lysosome, participation in an inflammatory protease cascade, and trimming of peptides for antigen presentation.
What are the official names of this protein?
Probable serine carboxypeptidase CPVL.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
Protein: YDJG_BACSU
Sequence: MIISYKCPNCGSDMAFDSETGSLSCSSCGRQDNIESLPKENIAARFSDDEAKEYQCKNCGAVLITEAETTATTCSFCGGAAILADRLSGHLAPAKVIPFTISKQEAEQAFRKWCKKGLLTPRGFMSADRIKSITGMYIPFWMFDLNSEVQVRANCTRVHQYEEGDYICTETEHFEAFRDINLDYLKIPVDASEKMKDELMDKLEPYSYEELKDFQTAYLAGYIAEKYNYTDEELFPRAKEKISSYIDSYIHSTFSGYTSVNVRDKHIHTKNVNSFYVLLPVWMVSYDYERAEHIFAMNGQTGKVVGKPPISRGKVAAWFSGIAGGTFLALKLVSLMMGGGF
What are the official names of this protein?
Uncharacterized protein YdjG.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RLME_PSEPG
Sequence: MVQRSKSSANWLREHFNDPFVKQAQKDGYRSRASYKLLEIQEKDRLIRPGMSVIDLGAAPGGWSQVTSRLIGGQGRLIASDILEMDSIADVTFIQGDFTHDEVLQRILEAVGDSHVDLVISDMAPNMSGTPAVDIPRAMFLCELALDLATRVLKPGGDFLIKIFQGEGFDVYLKDVRSKFDKVQMRKPSSSRDRSREQYLLGRGFKGA
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCMA_ZYMMO
Sequence: MGRKRLSDFGNARLACHDVSCLRGDRLLFTHLSFEVKAGEAVLITGANGIGKSSLLRLLAGFLKPFSGHIEKWGRVAFADEALAMDRHLPLEKALAYWAALDGVLGAEKEAMAVMALDILADSPVRLLSTGQRKRAVLARLLASQAAIWLLDEPANGLDAASVRALIEMIEHHRQKGGIILAVSHQGLDMADYKTLSLENFVANSGQSSGFFDLLDESHFS
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MSRA_LEPBJ
Sequence: MEQATLGGGCFWCLEAVYQMVEGIESVVSGYAAGQTKNPDYRSVCSGTTGHAETVQITFDSKVISYFEILEIFWISHDPTTLNRQGNDVGTQYRSIILYHSPEQKKQAEQSIQKAGEHFSDPIVTQVEILKEFYPAEDYHQNYFRTNPKQAYCHYVIKPKIDKYLKTGFKVKKEGS
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: MZM1_AJECN
Sequence: MAATTAPNPLAAYRFLLRATRIAFQGDFTTLHAARAEARKQFDQHRQQGVDTPMRIQHAMETAEILRTNVVQGVKISGDGEEADRYASILVMRRFRGEYEGEDERREKEREARGGCELRIHEHIERGDNDSIKTAGKNERVKVAVGKACSNTQ
What is the function of this protein?
Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex.  Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.  Modulates the mitochondrial matrix zinc pool (By similarity).
What are the official names of this protein?
Mitochondrial zinc maintenance protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. MZM1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: GP_HANTB
Sequence: MWSLLLLAALVGQGFALKNVFDMRIQCPHSVNFGETSVSGYTELPPLSLQEAEQLVPESSCNMDNHQSLSTINKLTKVIWRKKANQESANQNSFEVVESEVSFKGLCMLKHRMVEESYRNRRSVIYYDLAGNSTFCKPTVYMIVPIHACNMMKSCLIGLGPYRIQVVYERTYCTTGILTEGKCFVPDKAVVSALKRGMYAIASIETICFFIHQKWNKYKIVTAITSAMGSKCNNTDTKVQGYYICIIGGNSAPVYAPAGEDFRAMEVFSGIITSPHGEDHDLPGEEIATYHISGQIEAKIPHTVSSKNLRLAAFAGIPSYSSTSILAASEDGRFIFSPGLFPNLNQSVCDNNALPLIWRGLIDLTGYYEAVHPCNVFCVLSGPGASCEAFSEGGIFNITSPMCLVSKQNRFRAAEQQISFVCQRVDMDIIVYCNGQKKTILTKTLVIGQCIYTITSLFSLLPGVAHSIAIELCVPGFHGWATAALLITFCFGWVLIPACTLAILLVLKFFANILHTSNQENRFKAILRKIKEEFEKRKGSMVCEICKYECETLKELKAHNLSCVQGECPYCFTHCEPTETAIQAHYKVCQATHRFREDLKKTVTPQNIGPGCYRTLNLFRYKSRCYILTMWTLLLIIESILWAASAAEIPLVPLWTDNAHGVGSVPMHTDLELDFSLPSSSKYTYKRHLTNPVNDQQSVSLHIEIESQGIGADVHHLGHWYDARLNLKTSFHCYGACTKYQYPWHTAKCHFEKDYEYENSWACNPPDCPGVGTGCTACGLYLDQLKPVGTAFKIISVRYSRKVCVQFGEEHLCKTIDMNDCFVTRHAKICIIGTVSKFSQGDTLLFLGPMEGGGIIFKHWCTSTCHFGDPRDVMGPKDKPFICPEFPGQFRKKCNFATTPVCEYDGNIISGYKKVLATIDSFQSFNTSNIHFTDERIEWRDPDGMLRDHINIVISKDIDFENLAENPCKVGLQAANIEGAWGSGVGFTLTCQVSLTECPTFLTSIKACDMAICYGAESVTLSRGQNTVKITGKGGHSGSSFKCCHGKECSSTGLQASAPHLDKVNGISELENEKVYDDGAPECGVTCWFKKSGEWVMGIINGNWVVLIVLCVLLLFSLILLSILCPVRKHKKS
What is the function of this protein?
Forms homotetramers with glycoprotein N at the surface of the virion (By similarity).  Attaches the virion to host cell receptors including integrin ITGAV/ITGB3 (By similarity).  This attachment induces virion internalization predominantly through clathrin-dependent endocytosis (By similarity).  May also bind to host C1QBP for virus entry into the host cell (By similarity).  Class II fusion protein that promotes fusion of viral membrane with host endosomal membrane after endocytosis of the virion (By similarity).
What are the official names of this protein?
Envelopment polyprotein, M polyprotein.
What is the protein family that this protein belongs to?
Belongs to the hantavirus envelope glycoprotein family.
What are the subcellular locations of this protein?
[Glycoprotein N]: Virion membrane; Multi-pass membrane protein. Host cell surface. Host Golgi apparatus membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein. Host mitochondrion. Note=Interaction between glycoprotein N and glycoprotein C is essential for proper targeting of glycoprotein N to the host Golgi complex, where virion budding occurs. SUBCELLULAR LOCATION: [Glycoprotein C]: Virion membrane; Single-pass type I membrane protein. Host cell surface. Host Golgi apparatus membrane; Single-pass type I membrane protein. Host endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Budding probably takes place at the host Golgi (Probable). Glycoprotein C cytoplasmic tail is important for efficient Golgi localization (By similarity).
Protein: RLMN_NITSB
Sequence: MKNILDLTKEELQQEVTPKFRANQIYQWIYQKGAKDFESMSNLPKSMREELKEKFTITPPKILNVEVSKDGSKKYLLGLQDGHTVESVLLPMKKEERDEKGNILKEARYTVCVSSQVGCKVGCEFCLTAKGGFVRNLTPGEIVEQVLTIREDNNIPANRRVNIVYMGMGEPLDNLENVAKAVKIFSDEHGMSISPRRQTISTSGLAPKIKKLGEMNLGVLLAISLHAVDDELRQKLMPINKAYNIESVIQAVKEFPIDQRKRVMFEYLMIKNLNDDLKAAKKLVKLLHGIKAKVNLIYFNPYPGSPFQRPEPKDVEAFQKYLLDHGVLCTIRESKGLDISAACGQLKEKSHGCTL
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_SERP5
Sequence: MNSTDKLDSHTPMMQQYLRLKAQHPEILLFYRMGDFYELFYDDAKRASQLLDISLTKRGASAGEPIPMAGVPHHAVENYLAKLVQLGESVALCEQIGDPATSKGPVERKVVRIVTPGTITDEALLQERQDNLLAAIWQDARGFGYATLDISSGRFRVAEPADIETMAAELQRTNPAELLYPETFEQMSLIEQRHGLRRRPLWEFEPETARQQLNLQFGTRDLTGFGVEQAHQALRAAGCLLQYVKDTQRTSLPHIRGITMERQQDGIIMDAATRRNLELTQNLSGGSENTLAAILDRSVTAMGSRMLKRWLHMPTRDIKVLNNRQQAIGSLQDLYSDLQPSLRQVGDLERILARLALRSARPRDLARMRHAFQQLPDIHALLKGVETPYVQQLLSQVGQFDELQDLLERAVVEAPPVLVRDGGVIAPGYNSELDEWRALADGATDYLDRLEIREREKLGLDTLKVGFNGVHGYYIQVSRGQSHLVPIHYVRRQTLKNAERYIIPELKEYEDKVLTSKGKALAIEKGLYEELFDLLLPHLGDLQQSAAALAELDVLANLAERAETLNYACPTISEQPGVRITEGRHPVVEQVLSEPFISNPLSLSPQRRMLIITGPNMGGKSTYMRQTALIVLMAHIGSYVPASKAVIGPVDRIFTRVGAADDLASGRSTFMVEMTETANILHNATENSLVLMDEIGRGTSTYDGLSLAWACAENLASRIKAMTLFATHYFELTTLPEKMEGVVNVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPREVIKRARQKLRELEAISSHTATGTVDATQMTLLNEETSPAVEALEALDPDSLSPRQALEWIYRLKNMV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: 2SS_SOYBN
Sequence: MTKFTILLISLLFCIAHTCSASKWQHQQDSCRKQLQGVNLTPCEKHIMEKIQGRGDDDDDDDDDNHILRTMRGRINYIRRNEGKDEDEEEEGHMQKCCTEMSELRSPKCQCKALQKIMENQSEELEEKQKKKMEKELINLATMCRFGPMIQCDLSSDD
What is the function of this protein?
Binds to mammalian chromatin, preventing the normal formation of the kinetochore complex in the centromere and leading to the disruption of mitosis (PubMed:10331812).
What are the official names of this protein?
2S seed storage albumin protein, 2S albumin, GM2S-1, Napin-type 2S albumin 3.
What is the protein family that this protein belongs to?
Belongs to the 2S seed storage albumins family.
Protein: FXD3A_XENLA
Sequence: MTLSGSGSASDMSGQTVLSADDADIDVVGEGDEALDKDSECESTAGHTDEVGELGGKEIPRSPSGSGTEAEGKGESQQQQQEGIQNKPKNSLVKPPYSYIALITMSILQSPQKKLTLSGICEFISNRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKRQQQDSLREQTALMMQSFGAYSLASPYGRHYGLHPAAYTHPAALQYPYIPPVGHMLPPAVPLLPSSELTRKAFSSQLSPSLQLQLSSLSSTAASIIKSEPSSRPSFSIENIIGVSAASSAAPHTFLRPPVTVQSALMSHQPLALSRSTAAIGPILSVPTNLISGQFLPTAAAAVAKWPAQ
What is the function of this protein?
Transcriptional repressor that is an essential upstream regulator of neural crest determination and mesoderm induction.  Functions by recruiting the transcriptional corepressor tle4.  Also acts in a negative auto-regulator loop by inhibiting the transcription of its own gene.
What are the official names of this protein?
Forkhead box protein D3-A, FoxD3-A, FoxD3a, Fork head domain-related protein 6, FKH-6, Forkhead protein 6, xFD-6, xFKH6.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y059_NPVOP
Sequence: MYHLPDTLYEQEKMPRRAKRLFVDTFSQHHKLNAGDEEAAMQKARQALEERYVRVNDLQWIPRRAAYEIIRDDMSSDSDGPAASPPGDHARPNRDKRRVSYSSSDSSARSSDDQLISARGSDDQLISTRSSDDHLVGAGKARRPARKKKRIGKVVASQKFVGGGAQYSTDDDEDDY
What are the official names of this protein?
Uncharacterized 19.9 kDa protein.
Protein: NDPA_SALDC
Sequence: MSLDINQIALHQLIKRDEQNLELVLRDSLLEPTTTVVEMVAELHRVYSAKNKAYGLFNEESELAQALRLQRQGEEDFLAFSRAATGRLRDELAKYPFADGGIVLFCHYRYLAVEYLLVTVLNNLSSMRVNENLDINPTHYLDINHADIVARIDLTEWETNPQSTRYLTFLKGRVGRKVADFFMDFLGASEGLNAKAQNRGLLQAVDDFTAEAQLDKAERQNVRQQVYSYCNEQLQAGEEIELESLSKELSGVSEVSFSEFTAEKGYELEESFPADRSTLRQLTKYAGSGGGLTINFDAMLLGERIFWDPATDTLTIKGTPPNLRDQLQRRTSGGK
What are the official names of this protein?
Nucleoid-associated protein YejK.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: GATA_LEPBL
Sequence: MNEILRKSYAELKSSLSLGKISATELATACIERIKEVDGSVKAFLSLDEKRILDAASESDARRKSGNPLSEFDGMPIAIKDNICIRDSITSCASKILENYKSPFHATVIEKLIAKGFVLIPRANMDEFAMGSSTENSAFQTTRNPFDLERIPGGSSGGSAAAVAASMVPLALGSDTGGSVRQPASLCGLYGLKPTYGTVSRYGLVAYASSLDQIGPFSKELQGCIDLYSVISGKDERDSTSLNHPGFSAPWTPDFKGLKIGTIKMTSEIQPEVVKAYEKVLNQLKEKGATLVELDFSKFDFAIPIYYIIATAECSSNLSRFDGIRFGSRKDKTGKLEDLFVDSRTTGFGSEVKRRILLGTFSLSAGYYDAYYGTAQKARVLIRKEYDSFFSKVDFILQPTSPTTAFKVGEKTKDPIQMYKADIWTTSVNLAGIPAISVPMGTDEKGLPIGLQITAPHFQEGKLFGAAQAIGALEDLNIKFPENIG
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: PA2A1_NAJAT
Sequence: MTPAHLLILAAVCVSPLGASSNRPMPLNLYQFKNMIQCTVPSRSWWDFADYGCYCGRGGSGTPVDDLDRCCQVHDNCYNEAEKISGCWPYFKTYSYECSQGTLTCKGGNNACAAAVCDCDRLAAICFAGAPYNNNNYNIDLKARCQ
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that has high affinity for muscarinic acetylcholine receptors mAChRs (CHRM) and has the ability to activate them.  In guinea-pig ileum, produces an onset and dose-dependent contraction.  Has also weak anticoagulant activity.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 1, svPLA2, Muscarinic protein, MP, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GLYA_SHESA
Sequence: MLKKDMNIADYDPELFNAIQNETLRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGGCEYVDVVETLAIERAKQLFGATYANVQPHSGSQANSAVYMALLKPGDTVLGMNLAHGGHLTHGSPVNFSGRLYNIIPYGIDESGKIDYDEMERLAVEHKPKMMIGGFSAYSGIVDWARMREIADKIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTSTTHKTLAGPRGGIILSAADDEELYKKLNSAVFPGGQGGPLMHVIAGKAVAFKEALEPEFKAYQQQVVKNAKAMVEVFLERGYKIVSGGTDNHLMLVDLIGRDLTGKEADAALGSANITVNKNSVPNDPRSPFVTSGVRIGTPAITRRGFKEAEAKELTGWICDILDDAHNPAVIERVKGQVLALCARFPVYG
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.