PharMolix/UniProtQA huggingface dataset:
Protein: KCNG1_HUMAN
Sequence: MTLLPGDNSDYDYSALSCTSDASFHPAFLPQRQAIKGAFYRRAQRLRPQDEPRQGCQPEDRRRRIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMVEREEEDDALDSEGRDSEGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQGHCSQMCHNVFIVESVCVGWFSLEFLLRLIQAPSKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERVMFRRAQFLIKTKSQLSVSQDSDILFGSASSDTRDNN
What is the function of this protein?
Potassium channel subunit that does not form functional channels by itself.  Can form functional heterotetrameric channels with KCNB1; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 (PubMed:19074135).
What are the official names of this protein?
Potassium voltage-gated channel subfamily G member 1, Voltage-gated potassium channel subunit Kv6.1, kH2.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. G (TC 1.A.1.2) subfamily. Kv6.1/KCNG1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Colocalizes with KCNB1 at the plasma membrane (PubMed:19074135).
Protein: RL28_CAMC1
Sequence: MSKRCAITGKGPMVGNNVSHANNKTKRRFLPNLRTIRVTLEDGTTRRIKVAASTLRTMKKQSN
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: DXS_CUPPJ
Sequence: MTYALLKKIDAPADLRKLDRRELRTLADELRAYVLESVSQTGGHLSSNLGTVELTIALHYVFHTPDDRVVWDVGHQSYPHKILTGRRERMNTLRQFGGISGFPRRSESQYDTFGTAHSSTSISAALGMALGARTLGEQRVSIAVIGDGAMTAGMAFEALNNAGVYKDLPLVVVLNDNDMSISPPVGALNKHLARLLSGQFYAATKKGIEKVLSVAPPVLEFAKRFEEHAKGMMVPATLFEEFGFNYIGPIDGHDLDSLVPTLQNIRKRALEGAGPQFLHVVTKKGQGYKLAEADPILYHGPGKFNPAEGIRPAAKPARKTYTQVFGEWLCDMAAADKRLIGITPAMREGSGMVEFEKRFPERYYDVGIAEQHAVTFAGGMACEGLKPIVAIYSTFLQRGYDQLIHDVALQNLPVVFALDRAGLVGADGATHAGAYDIAYLRCIPNMMVMTPSDENECRQLLTTAFHQNCPTAVRYPRGAGQGVATEAVLKDVPVGKGVMRRTGGARSGQRVAFLGFGSMVHPALGAAQALDASVADMRFVKPLDVELVKRLAEEHNYLVTVEEGSVMGGAGSAVLEALAEAGIDIPVLVLGLPDRFIDHGDPALLLSQCGLDAAGIERSVRERFGIGQAPVAVASRVA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: MQO_XYLF2
Sequence: MKKSLKELTGLIVAFALATLLFLYWPLYQRSVPKANNDAPVDVVLIGGGIMSVTLGTYLQELQPDWKIELFERLNGIAQESSDGWNNAGTGHSAFAELNYTPELQDGTIEIKRAIKIAEQFEISREFWSHQVRHGRLPAPTEFINATPHMSFVWGEDRIEYLRKRHNALIKNPLFYGMQFSTDPAIIQKWAPLLMEGRTQDQKVAATYMPLGTDVNFGVITRDLAKHLQDSQNFALHLDHEVTALRQNPDKTWNVTVKDLNNGQERSIKSRFVFIGAGGAALKLLQLSGIPESKDYAGFPVGGQFLSFENTAITKRHNVKAYGMAESGSPPMSVPHLDARKLDGKSIVLFGPFALYSTKFLKNGSWFDLYSSVNHHNAAGMLSVGKNNIDLVKYLMKQATLTDADRHAELLKYFPNAKPTDWTLVTAGQRVQIIKRDPDKGMILQFGTEIVMDKDHTLATLLGASPGASTSPSIMLDLLAKAFPQQMKNGWETQLKKIIPSYGQHINDSPALTNKIRRMTSETLSLPYLEVPDKSATPADPTIAPKNQHSTTYNANSEMQAL
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: RL14_AMOA5
Sequence: MIQQETRLNVADNSGAKQVQCIRVLGGTKKRYASVGDRIVVSVKSASPAGNIKKGAVSKAVVVRTKKEVRRKDGSYIRFDDNAAVLLQNNDELRGTRISGPVARELREKEFMKVVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: SPG1_DICDI
Sequence: MNIKNSLILIISTIFVLSMINGGLTSDPTCVGAPDGQVYLFSSWDFQGERYVYNISQGYLSLPDGFRNNIQSFVSGADVCFVKWYPSEQYQITAGESHRNYAALTNFGQRMDAIIPGNCSNIVCSPK
What are the official names of this protein?
Spore germination protein 1, SPG1.
What is the protein family that this protein belongs to?
Belongs to the Dictyostelium gerABC family.
What are the subcellular locations of this protein?
Secreted.
Protein: AMPA_METPP
Sequence: MDFRILATSTSSLSKVSADALLIVVAGDPKQQGLDDPLDRVLSDAIAAGDLAFKAGRTLYLHRPLGVKAARVVFAVAGDAGPKAFKSAVAAGLGLIKPLGVKHLAVAASGAIEDSHAEAAAAAASDATYSYRHTKPSASPAPALQKITLLVDKAEAKAAQTGLSRGAAIALGVALARECANRPGNHCTPSFLAAEARKLAKLPRIKVDVLDRKACEKLGMGSFLAVAQGSDEPPKFIVLRYDGASRSDAPVVLVGKGITFDTGGISIKPAAEMDEMKYDMGGAASVLGSFRAVAELQPQVNVVGLIPSCENMPSGRAIKPGDVVTSMSGQTIEVLNTDAEGRLILCDALTYAERFKPAVVIDIATLTGACVIALGHHRSGLFSADDALADALLDAGSAGLDPAWRMPLDDEYEEALRSNFADMGNVGGRAGGAITAAMFLKKFTAKYRWAHLDIAGTAWKSGAAKGATGRPVPLLTHFVLSRTR
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPR_SIVS4
Sequence: MAERPPEDEAPQREPWDEWVVEVLEELKEEALKHFDPRLLTALGNYIYDRHGDTLEGAGELIRILQRALFIHFRSGCAHSRIGQSRGVL
What is the function of this protein?
Stimulates gene expression driven by the HIV-2 LTR.  Prevents infected cells from undergoing mitosis and proliferating, by inducing arrest or delay in the G2 phase of the cell cycle.  Cell cycle arrest creates a favorable environment for maximizing viral expression and production (By similarity).
What are the official names of this protein?
Protein Vpr, R ORF protein, Viral protein R.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: ATS10_HUMAN
Sequence: MAPACQILRWALALGLGLMFEVTHAFRSQDEFLSSLESYEIAFPTRVDHNGALLAFSPPPPRRQRRGTGATAESRLFYKVASPSTHFLLNLTRSSRLLAGHVSVEYWTREGLAWQRAARPHCLYAGHLQGQASTSHVAISTCGGLHGLIVADEEEYLIEPLHGGPKGSRSPEESGPHVVYKRSSLRHPHLDTACGVRDEKPWKGRPWWLRTLKPPPARPLGNETERGQPGLKRSVSRERYVETLVVADKMMVAYHGRRDVEQYVLAIMNIVAKLFQDSSLGSTVNILVTRLILLTEDQPTLEITHHAGKSLDSFCKWQKSIVNHSGHGNAIPENGVANHDTAVLITRYDICIYKNKPCGTLGLAPVGGMCERERSCSVNEDIGLATAFTIAHEIGHTFGMNHDGVGNSCGARGQDPAKLMAAHITMKTNPFVWSSCSRDYITSFLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRTCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTDDCPPGSQDFREVQCSEFDSIPFRGKFYKWKTYRGGGVKACSLTCLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETIEGVFSPASPGAGYEDVVWIPKGSVHIFIQDLNLSLSHLALKGDQESLLLEGLPGTPQPHRLPLAGTTFQLRQGPDQVQSLEALGPINASLIVMVLARTELPALRYRFNAPIARDSLPPYSWHYAPWTKCSAQCAGGSQVQAVECRNQLDSSAVAPHYCSAHSKLPKRQRACNTEPCPPDWVVGNWSLCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPVLEACHGPTCPPEWAALDWSECTPSCGPGLRHRVVLCKSADHRATLPPAHCSPAAKPPATMRCNLRRCPPARWVAGEWGECSAQCGVGQRQRSVRCTSHTGQASHECTEALRPPTTQQCEAKCDSPTPGDGPEECKDVNKVAYCPLVLKFQFCSRAYFRQMCCKTCHGH
What is the function of this protein?
Metalloprotease that participate in microfibrils assembly.  Microfibrils are extracellular matrix components occurring independently or along with elastin in the formation of elastic tissues.
What are the official names of this protein?
A disintegrin and metalloproteinase with thrombospondin motifs 10, ADAM-TS 10, ADAM-TS10, ADAMTS-10.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: CBPA_ECOLU
Sequence: MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFSRQFQHGDGQSFNAEDFDDIFSSIFGQHARQSRQRPATRGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTLNVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVSPWEAALGAKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMPPKPDENTAALWQQLADAQSSFDPRKDWGKA
What is the function of this protein?
DNA-binding protein that preferentially recognizes a curved DNA sequence.  It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock.  Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK.  Its activity is inhibited by the binding of CbpM.
What are the official names of this protein?
Curved DNA-binding protein.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: Y217_HAEIN
Sequence: MSNYRRDFTKGGLYFFTIVLQDRTKSYLTDYINEFRSAYKQTCEHYPFETVAICILPDHIHLLMQLPENDDNYAIRIAYLKTQFTRQLPKECRQFNKNRQKYRESGIWQRRFWEHLIRDDKDLANHLDYIYYNPVKHGYVEVVKDWPYSSFHRDVKAEIYPEDWGGNPDLKIKGDI
What is the function of this protein?
Transposase responsible for transposition an insertion sequence (IS) element.  Transposition occurs in 2 main steps, excision from the donor DNA 'top strand' into a single strand circle and its subsequent reinsertion into the DNA target.  This increases the copy number of the IS.
What are the official names of this protein?
Putative REP-associated tyrosine transposase.
What is the protein family that this protein belongs to?
Belongs to the transposase 17 family. RAYT subfamily.
Protein: SYL_METJA
Sequence: MMVMIDFKEIEKKWQKRWEEAKIFEANPDDREKFFITAAFPYLNGVLHAGHLRTFTIPEVVARFQRMKNKNVLWTFGYHVTGTPILGLAELIKNRDEKTIWAYTELHGIPKEELLELTTPEKIVEYFSKKAEEAFKRMGFSLDWRRNFKTDDKVFNKFIEWQFHKLKEKGLIVKGSHPVRYCPRCDNPVEDHDILVGENATLVEYILIKFTTEDGCIMPMATLRPETVFGVTNVWVNPEATYVKAKVYLEKETENGIELIENGIWIMAKECAEKLKHQDRKIEIIEEFKGEQLINKKVKNPVTGKEVPILPAKFVKTNIGTGCVMSVPAHAPYDYIALRDLGLVDEIGLIPLINVPGYGKYPAKEIVEKMGIKSQEEEDKLEEATKKIYKDEFHKGVLNENCLDYEGIPVREIKDKLTKDLIDKGLAEIMYEFSEEKVICRCGTPCIVKMVKGQWFIKYSDEKWKELAHKCIDKMRFIPENLRQVFHEKIDWMKDKACVRRRGLGTKFPFEEGWVIESLSDSTIYPAYYTVAKYINQHNIKPEQLTLELFDYVFLGKGDVDKIAKETGIPKDIIEGMRKEFIYYYPVDWRCSAKDLIPNHLTFYIFNHVAIFPEEFWPRGIVVNGYVTIEGKKLSKSKGPVLPVLEVAEKFGADVGRFYITTCAELPQDADIKFKEMENTKKVLERLYLFAKEIAERRGETGEEFSYIDKWLLSRLYKAVKQYDEYMENFELRKAGILLYQLLDDLKWYRRRGGNNIRVLEEFLEVIIKLMMPFTPHLCEEMWEILGKEGFVSLAKFPEVKEEFINDEIEKGEEYLKAVMEDIKEIINVAKVQPKRIYLYTADDWKYEILKIIKENEGKTIKELMPIIMKNPEFRKYGKEIPKLVNQLIKLNAEIINEVEVLENAKEFLKKEVGVEDIIINGEDKANKKRVAIPFKPAIYLE
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_SHIBS
Sequence: MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVAELVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVSSDDVEMAINHIKSQLRATGEREVPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RL24_MYCGI
Sequence: MKVRKGDTVLVISGKDKGAKGKVLVAYPDRNKVLVEGVNRIKKHTAESRTERGAASGGIVTQEAPISVSNVMLLDSDGKPTRVGYRKDDETGKNVRIAKSNGKDL
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: CWP29_ARATH
Sequence: EDLPEK
What are the official names of this protein?
36 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: OL149_MOUSE
Sequence: MKNLSVVTQFILLGIPHTEGVETMLFVLFFSFYIFTLVGNLLILLAIVSSSRLHTPMYFFLCQLSVCDIFFPSVSSPKMLFYLSGNTPAISYAGCVSQLFFYHFLGGTECFLYTVMAYDRFVAICYPLRYSVIMSHRICAFLAMGTAVFGCIHSTFLTTLTFQLPYCGPKDVNYYFCDIPVVMKLACADTSTLEMVGFISVGLMPLSCFFFILTSYSCIVRSILQIRSTEGRHRAFSTCSAHFTAILLFYMPVIFIYLRPTPSPWLDATVQILNNLVTPMLNPLIYSLRNKEVKSSLWTVLHLLCFLPKHL
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 149, Odorant receptor M31, Olfactory receptor 224-8, Olfactory receptor 7G.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MUTS_ECO57
Sequence: MSAIENFDAHTPMMQQYLKLKAQHPEILLFYRMGDFYELFYDDAKRASQLLDISLTKRGASAGEPIPMAGIPYHAVENYLAKLVNQGESVAICEQIGDPATSKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDSKGFGYATLDISSGRFRLSEPADRETMAAELQRTNPAELLYAEDFAEMSLIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLVGFGVENAPRGLCAAGCLLQYAKDTQRTTLPHIRSITMEREQDSIIMDAATRRNLEITQNLAGGAENTLASVLDCTVTPMGSRMLKRWLHMPVRDTRVLLERQQTIGALQDFTAELQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELRAQLETVDSAPVQALREKMGEFAELRDLLERAIIDTPPVLVRDGGVIASGYNEELDEWRALADGATDYLERLEVRERERTGLDTLKVGFNAVHGYYIQISRGQSHLAPINYMRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKQLYEELFDLLLPHLEALQQSASALAELDVLVNLAERAYTLNYTCPTFIDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYMRQTALIALMAYIGSYVPAQKVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATEYSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKMEGVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELESISPNAAATQVDGTQMSLLSVPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RBSD_BACMK
Sequence: MKKHGVLNSEIAAVLASLGHTDTIVIADCGLPIPDGVKRIDLAVEIGKPSFLDVLQVVADDMAIEKVMLAEEVIINNAEVNKEVEMRLIEPAFEYVSHKEFKEHTKRAKAIIRTGEATPYANVILHAGVIF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_PELPD
Sequence: MLVKEFDYHLPEELIARYPAPERDGSRLMLLNRESGTIGHGLFRDIADHLRPGDLLVLNDTRVIPARLFGRKATGGRVEIFLVRRQETQAERWSCLMRSSKGMRPGQLITLAGAMTALVVERLEPEGWLLEFQGAEPFSVWLEREGEMPLPPYLQRPAESGDQLRYQTVFARSAGAVAAPTAGLHFTPELLERLAERGVATACLTLHTGPGTFQPLRVERVQDHRIHSERYHISAETCQAIAETKQRGGRVVAVGTTSARTLEYAADEKGGLCPGSGDADIFIYPGYRFRVVDALVTNFHLPESTLIMLVSAFAGKEYVFHAYHEAARLGYRFYSYGDAMFIE
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPIA_HEMPU
Sequence: MAKPQVFFDLQANGENLGRIVMELRADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPGFMCQGGDFTRHNGTGGKSIYGEKFADENFTLKHTQPGILSMANAGVNTNGSQFFICTAVTSWLDGKHVVFGAVTQGLDIIKKVESYGSDSGKTSKKITIADCGQL
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase, PPIase, Cyclophilin, Cyclosporin A-binding protein, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR6_CAEEL
Sequence: MSSLAEIASRPENLELLAEGKTKQIFDIKGEKDYVLIRSKDSLTAFNAVRKNELEGKSRIASKTTSNVFEYLQLLGLPTHFEKSISETEFVARKCTMIPIEWVARRVATGSFLKRNPGVKEGFRFNDLKLETFFKDDANDDPQWTDEQIVSNGLMIDHLKIGREEISLMKKMTKLVFRALEKGWALSNSALIDMKIEFGVTVEGEILLADVIDNDSWRVWPENDRRLQLDKQVYRDMKEVTEEGLALVLKNYTKVMDITATFSKHQQKCHVLVIMGSGSDGVFARKISDEAKKFGLETTLKVSSAHKTTSDTLEVIADFEESGVPTVVIAVAGRSNGLGPVIAGNSSLPVINCPPPSESTSLDIWSSLRMPNGIGCTTVLDPSEAALAAAKILASHNHIVFGKVLTAQLKNQINIYNANRKLE
What are the official names of this protein?
Probable multifunctional protein ADE2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the AIR carboxylase family. Class II subfamily.
Protein: FABA_SHELP
Sequence: MNKANSFSKEELVTCGHGNLFGANSPRLPIDNMLMIDRITKINDDGGEFGKGEIVAELDIDPSLWFFGCHFETDPVMPGCLGLDAMWQLVGFFLGWEGAEGKGRALGVGEVKFTGQVLPDAKKVTYKLTIKRKVYRKLVMGIADAVMEVDGREIYSATDLKVGIFTDTSSF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BTNL8_HUMAN
Sequence: MALMLSLVLSLLKLGSGQWQVFGPDKPVQALVGEDAAFSCFLSPKTNAEAMEVRFFRGQFSSVVHLYRDGKDQPFMQMPQYQGRTKLVKDSIAEGRISLRLENITVLDAGLYGCRISSQSYYQKAIWELQVSALGSVPLISITGYVDRDIQLLCQSSGWFPRPTAKWKGPQGQDLSTDSRTNRDMHGLFDVEISLTVQENAGSISCSMRHAHLSREVESRVQIGDTFFEPISWHLATKVLGILCCGLFFGIVGLKIFFSKFQWKIQAELDWRRKHGQAELRDARKHAVEVTLDPETAHPKLCVSDLKTVTHRKAPQEVPHSEKRFTRKSVVASQSFQAGKHYWEVDGGHNKRWRVGVCRDDVDRRKEYVTLSPDHGYWVLRLNGEHLYFTLNPRFISVFPRTPPTKIGVFLDYECGTISFFNINDQSLIYTLTCRFEGLLRPYIEYPSYNEQNGTPIVICPVTQESEKEASWQRASAIPETSNSESSSQATTPFLPRGEM
What is the function of this protein?
May stimulate primary immune response.  Acts on T-cell stimulated sub-optimally through the TCR/CD3 complex stimulating their proliferation and cytokine production.
What are the official names of this protein?
Butyrophilin-like protein 8.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. BTN/MOG family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CYSD_HAHCH
Sequence: MTDYNLTHLKQLEAESIHIIREVAAEFERPVMLYSIGKDSSVMLHLARKAFFPGKPPFPLMHVDTTWKFQDMITFRDQQAAKFGLDLIVHINEDGVRQGIGPFTHGSAKHTDVMKTESLKQALNKYKFDAAFGGARRDEEKSRAKERVYSFRDSNHRWDPKNQRPELWNLYNGKINKGESIRVFPLSNWTELDIWQYIYLENIELVPLYFSAKRPVVERDGTMIMVDDDRMPLKPGETPMMKDVRFRTLGCYPLTGAIESTATTLPEIIQEMLLTTSSERQGRVIDHDQAGSMEQKKREGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: PLSX_CHLFF
Sequence: MNVQIGIDLMGGDHSPLVIWEVLIDVLNSTASNSHFSFTAFASHEVQEQILSSCTYKECPKIIASDSFVTMDDSPLSAIRKKSSSMALGLDYLKEDKIDAFISTGNTAALITLSRTKIPVFPTVRRPALLVRVPTMRGCAVILDVGANVSVNPEEMLGFARMGLAYRQCIGEKEHPTIGLLNIGSEERKGTEAHRQTFRILRETFQDSFLGNIESGDVFSGSVDIVVADGFTGNIFLKTAEGVFDFLRHILGDKLESDVKRQLDYTIYPGSMVCGLSKLVIKCHGKACGRSLFNGISGSIDLARARVCQRILSSLS
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: SYH_SYNY3
Sequence: MGAIQAIRGTRDILPPETNYWQWVEAIAKSILDRALYQEIRTPIFEQTSLFERGIGEATDVVGKEMYSFTDRGDRPITLRPEGTAGVVRAYIEQNLQAAGGVQRLWYTGPMFRYERPQAGRQRQFHQLGVEVLGSADPRADVEVIALGTDILKALGLSNLSLALNSVGNGGDRQRYREALIAYLTPFKAELDPDSQDRLERNPLRILDSKAKRTQEIVQDAPSILDHLGVDSQRHFDQVQQLLTNLGIAYQLTPTLVRGLDYYTHTAFEIQSSDLGAQATVCGGGRYDGLVAELGGPVTPAVGWAMGLERLIILLQQMATPPAPSPDLYLISKGEKAEPQALILAQKLRNQGLAVALDLSASAFGKQFKRADKSGAIACLVLGDGEIATGTVQLKWLADKAQETLQLQDLMGNITELKQRLAGHREKYPHLTSNFSVTCHDPMDNLV
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_MANSM
Sequence: MKLVEVKHPLVKHKLGLMRAADVSTKHFRELATEVGSLLTYEATADLETEIVTIEGWCGPVEVQRIKGKKVTVVPILRAGLGMMDGVLEHIPSARISVVGMYRDEETLEPVPYFQKLASDIEERLAIVVDPMLATGGSMIATIDLLKQKGCKHIKVLVLVAAPEGIKALESAHPDIELYTASIDDHLNQDGYIIPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: TDH_KLEP3
Sequence: MKALSKLKAEEGIWMTDVPEPEVGHNDLLIKIRKTAICGTDVHIYNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVRGFKIGDRVSGEGHITCGHCRNCRAGRTHLCRNTIGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLASIFDPFGNAVHTALSFDLVGEDVLVSGAGPIGVMAAAVAKHVGARNVVITDVNEYRLELARKMGVTRAVNVAKENLNDVMAELGMTEGFDVGLEMSGAPPAFRSMLDTMNHGGRIAMLGIPPSDMSIDWTKVIFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFGIDDFQKGFDAMRSGQSGKVVLSWE
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_RICFE
Sequence: MKLSDFDFDLPTELIAQYPASERDNSDLLIATTPPIKTKFYNIIDYLKEGDLLVFNNSKVIKAKLNLERNITINLNQKLSDDSWSAFAKPARKLNIGDEFYSDNHKVIITEKFAMGEIKVKFELDNISVFEFLDKYGEMPLPVYIRRSKRHGEEEESSDEAISSQNPEIATESKRTPSNDDKLDSLRYQTIYSQIEGSVAAPTAGLHFTKEILDKLKAKGVQIAFVTLHVGAGTFLPVKTENIHEHKIHTEYCSITPETAEIINKAKQERRRIIAVGTTTLRTLESSCNNGVVKAGSFETDIFITPGFKFQTTDMLLTNFHFPKSTLFMLICAFAGFKEMHELYKYAIKEKMRFFSYGDATVLYRKV
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRL_BACSX
Sequence: MSNYPKYRVAAVQASPVLLDLDATIDKTCRLVDEAAANGAKVIAFPEAFIPGYPWWIWLGNADYGMKYYIQLYKNSVEIPSLAVQKLSSAGTNKVYFCVSVTEKDGGSLYLTQLWFDPNGDLIGKHRKLKATNAEKTIWGDGDGSMMPVFETEFGNLGGLQCWEHFLPLNVAAMASMNEQVHVASWPIGMPQEGHLFGPEQCVTATKYYAISNQVFCLLSSQIWTEEQRDKICETEEQRNFMKVGHGFSKIIAPNGMEIGNKLAHDEEGITYADIDLEQIIPGKFLIDSAGHYSTPGFLSLSFDRTEKKPIKHIGESAQETVTYEEIQYGNKANVKVHS
What are the official names of this protein?
Nitrilase.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.