PharMolix/UniProtQA huggingface dataset:
Protein: QUEA_GEOSL
Sequence: MLVTEFDYHLPPELIAQEPLVQRDATRLMTVERDGGGIGEIPFRGIVDLFRPGDLLVINDTRVIPARLLGRKESGGKTEIFLVRRRPGDHETWHCLIRSSKPPRPGVTVLLPEGVRAVVREPGDGETWLVSFTPGEGFQEWLDRNGAMPLPPYIRREADAADRDRYQTVFARNRGAVAAPTAGLHMTAGLLDEIAGRGVRVAPVTLHVGLGTFMPIRVERLEDHRMHRERYHIPPATADAINGCRREGGRVIALGTTVCRTLEQAAAADGTIAAGEGEADIFIYPGYRFKAVDALITNFHLPKSTLLMLVSAFAGRDLLFRAYGEAVARRFRFFSYGDAMFIF
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_CELJU
Sequence: MSEDFKLDATARNDLGKGASRRLRRLADQVPAIIYGGSKAPVNVSVSHNELLKHLQHEAFFSHVIDLNIDGTSESVILKDVQRHPSKAQVLHLDFLRVDKNTKLHKQVPLHFINEATSVGVKTQGGKVVHNLTQLDVTCLPQDLPEFIEVDLAAIEAGQILHISDLKLPKGVISTDLTKGADHDLAVVTILKAKGGESEEAAE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: UVRB_GLOVI
Sequence: MTDDRFVVSAPYRPTGDQPRAIAQLSAGALGGVTFQTLLGATGTGKTFTIANVIEKVGKPTLVLAHNKTLAAQLCNELREFFPDNAVEYFVSYYDYYQPEAYIPQTDTYIEKSASINDEIDMLRHSATRSLFERRDVIVVASVSCIYGLGMPEEYLRAAIPLKVGSNIDQRELLRQLVTVQYERNDIDLGRGRFRVRGDVVEIGPAYEDRIIRVEFFGDEVEAVRWLDPVTGEVVRSVNSLNIYPAKHFVTPEEQLEQACIAIEQELEARVAELEGENKLLEAQRIKQRTRYDLEMLREVGYCNGVENYSRHLAARRPGEAPSCLIDYFPQDWLLVVDESHVTIPQIRGMYNGDAQRKKVLIDHGFRLPSAADNRPLKAPEFWDKVRQAIFVSATPGDWEVELSGGGRDPETGRMAGEHVAEQIIRPTGVLDPEVFVRPVAGQVDDLLHEIHDRVARRERVLVTTLTKRMAEDLTEYFQERGVKVRYLHSEIQAIERIEILQALRQGDFDVLIGVNLLREGLDLPEVSLVAILDADKEGFLRAERSLIQTIGRAARHVRGQVIMYADRLTASMDKAISETERRRQIQRAYNAAHGLTPQPIVKRLDANSILDYLAVSRRLNQQELEAAAAAPAEVALADIPELVSQLEIQMRDAAKKLEFEKAAEYRDKIHKLRERLLGK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_STAAU
Sequence: MAKRDYYEVLGISKDASKDEIKKAYRKLSKKYHPDINKEEGADEKFKEISEAYEVLSDDNKRATIDQFGHDGPQGFGGQGFNGSDFGGFSGFGGGGFEDIFSSFFGGGSQRDPNAPQKGDDLQYTMTLTFEEAVFGTTKEISIRKDVTCETCHGDGAKPGTSKKTCSYCNGAGHVAVEQNTILGRVRTEQVCPKCNGSGQEFEEACPTCHGKGTENKTVKLEVKVPEGVDNEQQIRLAGEGSPGVNGGPAGDLYVVFRVKPSETFKRDGDDIYYKLNVSFPQAALGDEIKIPTLNNEVMLTIPAGTQTGKQFRLKEKGIKNVHGYGYGDLYVDIKVVTPTKLTDRQKELMKEFAQLNGEEINEQPSNFKDRAKRFFKGE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTAP_XENTR
Sequence: MAGVCAVKVGIIGGSGLDDPDILEGRLEKYVDTPFGKPSDALVLGKIKNVDCVLLASRHGRQHTIAPTNVNYRANIWALKSEGCTHILVTTACGSLREEIQPGDIVIVDQFIDRTTKREQTFYDGGPSCLPGVCHIPMAEPFCAKTREVLIDIAKRLGIKCHSKGAMITIEGPRFSSKAESQMFRLWGADVINMTTVPEVILAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKATSILLTAIPQIAAMDWTELLQSMKSTVQLSVMLPKH
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate.  Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis.  Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.  Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
What are the official names of this protein?
S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP, MTAPase.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PNP_STAAE
Sequence: MSQEKKVFKTEWAGRSLTIETGQLAKQANGAVLVRYGDTVVLSTATASKEPRDGDFFPLTVNYEEKMYAAGKIPGGFKKREGRPGDDATLTARLIDRPIRPLFPKGYKHDVQIMNMVLSADPDCSPQMAAMIGSSMALSVSDIPFQGPIAGVNVGYIDGKYIINPTVEEKEVSRLDLEVAGHKDAVNMVEAGASEITEQEMLEAIFFGHEEIQRLVDFQQQIVDHIQPVKQEFIPAERDEALVERVKSLTEEKGLKETVLTFDKQQRDENLDNLKEEIVNEFIDEEDPENELLIKEVYAILNELVKEEVRRLIADEKIRPDGRKPDEIRPLDSEVGILPRTHGSGLFTRGQTQALSVLTLGALGDYQLIDGLGPEEEKRFMHHYNFPNFSVGETGPVRAPGRREIGHGALGERALKYIIPDTADFPYTIRIVSEVLESNGSSSQASICGSTLALMDAGVPIKAPVAGIAMGLVTREDSYTILTDIQGMEDALGDMDFKVAGTKEGITAIQMDIKIDGLTREIIEEALEQARRGRLEIMNHMLQTIDQPRTELSAYAPKVVTMTIKPDKIRDVIGPGGKKINEIIDETGVKLDIEQDGTIFIGAVDQAMINRAREIIEEITREAEVGQTYQATVKRIEKYGAFVGLFPGKDALLHISQISKNRIEKVEDVLKIGDTIEVKITEIDKQGRVNASHRALEE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_BUCCC
Sequence: MINVLQEKTYIKMNKCVLNFKNDLNKIRANRATPELLDNIFIDYYGTHTALSKLSNIIIENNSTLKISLFDISIKNSVEKSIINSNLGLNPISSDSNIRIKIPALTEQRRKDIVKIIKNDAENTRISIRNIRREANIQIKTLLKEKEINQDIEKQVKLEIQRYTNLFIKKINDILSIKEKELLTI
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_ECOBW
Sequence: MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDVFNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIAIPPSLLNMYKELENTIPGFTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVVFLLWGSHAQKKGAIIDKQRHHVLKAPHPSPLSAHRGFFGCNHFVLANQWLEQRGETPIDWMPVLPAESE
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUDT7_HUMAN
Sequence: MSRLGLPEEPVRNSLLDDAKARLRKYDIGGKYSHLPYNKYSVLLPLVAKEGKLHLLFTVRSEKLRRAPGEVCFPGGKRDPTDMDDAATALREAQEEVGLRPHQVEVVCCLVPCLIDTDTLITPFVGLIDHNFQAQPNPAEVKDVFLVPLAYFLHPQVHDQHYVTRLGHRFINHIFEYTNPEDGVTYQIKGMTANLAVLVAFIILEKKPTFEVQFNLNDVLASSEELFLKVHKKATSRL
What is the function of this protein?
Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate (By similarity).  Cleaves CoA, CoA esters and oxidized CoA with similar efficiencies (By similarity).  Preferentially hydrolyzes medium-chain acyl-CoAs and bile acid-CoAs (By similarity).  Has no activity toward NDP-sugars, CDP-alcohols, (deoxy)nucleoside 5'-triphosphates, nucleoside 5'-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or thymidine-5'-monophospho-p-nitrophenyl ester (By similarity).  May be required to eliminate oxidized CoA from peroxisomes, or regulate CoA and acyl-CoA levels in this organelle in response to metabolic demand (By similarity).  Does not play a role in U8 snoRNA decapping activity (By similarity).  Binds U8 snoRNA (By similarity).  Exhibits decapping activity towards dpCoA-capped RNAs in vitro (By similarity).
What are the official names of this protein?
Peroxisomal coenzyme A diphosphatase NUDT7, Nucleoside diphosphate-linked moiety X motif 7, Nudix motif 7.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.
What are the subcellular locations of this protein?
Peroxisome.
Protein: RL33_BLOFL
Sequence: MAKETREIIYLFSSTGNGHFYTTTKNKRSHPEKIKLKKFDPIIKKHITYTEKK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RL23_CAMJD
Sequence: MADITDIKTILYTEKSLNLQEQGVVVIQTSPKMTKTGLKAVLKEYFGVTPKSINSLRMDGKVKRFRGRLGQRNDYKKFYVKLPEGVSLENAEA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RS8_POLAQ
Sequence: MSISDPIADMLTRIRNAQAVQKPVVLMPSSKVKVAIAKVLQDEGYIESFEIKGEAAKPVLHIDLKYYAGRPVIERIDRVSTPSLRIYKGRHDIPEVMNGLGIAIISTPQGVMTDRKARATGVGGEVICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RL21_DESVM
Sequence: MYAIIETGGKQFRVEEGAKIFVEKLVAEAGSEIVIDKVLMLGGGAFSVGAPYVEGAKVTAEVVEHGRGEKLIVFKKWRRNDSRKKQGHRQDFTALKIKAIQA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: GLNB2_METBA
Sequence: MKEVTAVVRPNKMSVTKDALDKIGYRRMTAIPVLGKGKQRGISGELNFYIQPKLLAKRYSTGMKYIPKRLLSIVVNDEDVDQVIKTIIGVNQTAQIGDGKIFVESIDEVIRIRTGEKGELALK
What is the function of this protein?
Could be involved in the regulation of nitrogen fixation.
What are the official names of this protein?
Nitrogen fixation nifHD1 region GlnB-like protein 2, ORF-123.
What is the protein family that this protein belongs to?
Belongs to the P(II) protein family.
Protein: PGK_ACAM1
Sequence: MSKKTIANLTSADLSGKRVLVRADFNVPLDGDGKITDDTRIRAALPTIQDLTSKGAKVILASHFGRPKGQVNESMRLTPVAARLSELLGQAVTKCDDCIGDEVAAKVGALQNGQVALLENVRFHSGEEANDPEFARQLASVADLYVNDAFGTAHRAHASTEGVTHHLSPSVAGYLIEKELKYLQAAIEGPQRPLAAIVGGSKVSSKIGVIETLLDKVDKLLIGGGMIFTFYKARGLAVGKSLVEEDKLDLARTLEAKAKEKGVALLLPSDVVVADNFAADANAQTVSINNIPDGWMGLDIGPNSVKEFQAALSDCKTVIWNGPMGVFEFDKFAAGTDAVAHSLAAITETGADTIIGGGDSVAAVEKVGVAEKMSHISTGGGASLELLEGKVLPGIAALDEA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_FRACC
Sequence: MARLSGVDLPREKRVEIALTYIFGIGRSRSRDTLAATAVNPDTRVRDLSEEEIVRLRDWIDANYRVEGDLNREIKQDIRRKMEIGCYQGLRHRRNLPVHGQRTHTNARTRKGPRRAIAGKKKAGKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RL36_PELUB
Sequence: MKIKSSLKSLKKRDLNSKLVRRRGRVYIINKTNPKFKARQK
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: Y2370_ARCFU
Sequence: MEIVSDKKISEKGIASAAELLYKGAKMLAHSCPECKMPLFEKDGKIFCPSCGREVVIEEDSAAKAESEEKPPESTKPAVKADYDEAVEKIEMAISKVCDMMVESRSVEEVRVLSDSLEKLVDALKKLRE
What are the official names of this protein?
UPF0148 protein AF_2370.
What is the protein family that this protein belongs to?
Belongs to the UPF0148 family.
Protein: OPPF_LACLS
Sequence: MSEILNLKDLKVYYPIRSGFFNRVTDNVLAVDGVDLTIHEGETVGLVGESGSGKSTIGKTIVGLEQMTSGQLIYKGQDVSKKKIRNQLKYNKDVQMIFQDAFSSLNPRKTIYDIIAEPIRNFEKIDANTENKRIHELLDIVGLPKQALEQYPFQFSGGQQQRIGIARAVATNPKLIVADEPVSALDLSVQAQVLNFMKLIQKDLGIAFLFISHDLGVVRHMTDNIAVMHNGRIVEKGTRRDIFDEPQHIYTKRLLSAIPSIDVTRRAENRKNRLKVEQDFEDKKANFYDKDGHALPLKKLSESHWAALPKGGENVESNY
What is the function of this protein?
Part of the binding-protein-dependent transport system for oligopeptides.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Oligopeptide transport ATP-binding protein OppF.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: C515B_DICDI
Sequence: MATLLLVIIFMITFIIYKNFDSKRKNKYPPGPINLPFIGGLYKLKPGKQHLSLNELYQKYGKVFSMKFGSYDTVILNEPDVIVEAFHLNSTSFMDRILLPSFEVVGKNQNIGFTQTEYWKKIRGILNISLTKSKTRLLEGLFNQEYFRFDQFIKKQLKSKSDTMFIRPYLKRLSFNIIYSYLFSETIPYEDELIPSDILDFIHASEELLVVLSRMPSDYIKVLRPFESHKKLKEICDRMSKFIKPRVDKKVELLDQDNPKCFIDYLILQIRSDPSQTIKIDAIQYIVLDLLVGGTDSTSSALEWMILFLSNHESIQEKLYNEICKNTNTNTTATTTENDNESYFPKLIEKNNYPLFNACVKETLRRSPPVPLGLPHLCSEDTEIGGYLIPKGTQIISNIYSASNCDKVFTDPLEFNPLRFIENSPPQTVTFSTGPRVCPGKNLSEDELFSFGTKLFKTFKFSRPNKNQLYDEVAILGITLEPKPFITKVSLRS
What are the official names of this protein?
Probable cytochrome P450 515B1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PPP5_RAT
Sequence: MAMAEGERTECAEPPRDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQKAFERAIAGDEHRRSVVDSLDIESMTIEDEYSGPKLEDGKVTITFMKDLMQWYKDQKKLHRKCAYQILVQVKEVLCKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSVSKRGVSCQFGPDVTKAFLEENQLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM
What is the function of this protein?
Serine/threonine-protein phosphatase that dephosphorylates a myriad of proteins involved in different signaling pathways including the kinases CSNK1E, ASK1/MAP3K5, PRKDC and RAF1, the nuclear receptors NR3C1, PPARG, ESR1 and ESR2, SMAD proteins and TAU/MAPT (PubMed:11523989, PubMed:12176367, PubMed:15546861, PubMed:16892053, PubMed:16549782).  Implicated in wide ranging cellular processes, including apoptosis, differentiation, DNA damage response, cell survival, regulation of ion channels or circadian rhythms, in response to steroid and thyroid hormones, calcium, fatty acids, TGF-beta as well as oxidative and genotoxic stresses (By similarity).  Participates in the control of DNA damage response mechanisms such as checkpoint activation and DNA damage repair through, for instance, the regulation ATM/ATR-signaling and dephosphorylation of PRKDC and TP53BP1 (By similarity).  Inhibits ASK1/MAP3K5-mediated apoptosis induced by oxidative stress (By similarity).  Plays a positive role in adipogenesis, mainly through the dephosphorylation and activation of PPARG transactivation function.  Also dephosphorylates and inhibits the anti-adipogenic effect of NR3C1 (By similarity).  Regulates the circadian rhythms, through the dephosphorylation and activation of CSNK1E (By similarity).  May modulate TGF-beta signaling pathway by the regulation of SMAD3 phosphorylation and protein expression levels (By similarity).  Dephosphorylates and may play a role in the regulation of TAU/MAPT (PubMed:15546861).  Through their dephosphorylation, may play a role in the regulation of ions channels such as KCNH2 (PubMed:16549782).  Dephosphorylate FNIP1, disrupting interaction with HSP90AA1/Hsp90 (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 5, PP5, Protein phosphatase T, PPT.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell membrane. Note=Predominantly nuclear. But also present in the cytoplasm. Translocates from the cytoplasm to the plasma membrane in a RAC1-dependent manner.
Protein: CML5_ORYSJ
Sequence: MAEVEVRVRQEQVAEFRETFAFFDKDGDGCITLEELDTVVRSLGQTPTREELAEMIRDVDVDGNGTIEFAEFLALMARKASRGGENGGGGDDSGDAADEELREAFKVFDKDQDGLISAAELRHVMISLGEKLTDEEVEQMIREADLDGDGQVNFDEFVRMMMLSDQ
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Calmodulin-like protein 5, Calmodulin-2, OsCAM-2.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: TRMD_BUCAI
Sequence: MKKKYNETIICFNIITIFPEMFYAITNYGIIGQAIKKKIININFFNPRNFSKNKYKSVDDRPYGGGPGMLMSFEPLYLAIQQAKSTSKNVTVIYLSPQGKELKQNHIEELLVKKKKIVFICGRYEGIDQRIIDNQVDEEWSIGSYILTGGELAAMVMIDAISRLIPGVIKTKKSIEEDSFTNDLLDYPNYTRPKIIKNMSVPQVLLSGNHNEIRLWRLKQSLGTTWIKRPDLIKKKY
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_GRAFK
Sequence: MSVRKLKPITPGQRFRVVNGYDAITTDKPEKSLLAPIKKSGGRNSQGKMTMRYKGGGHKKRYRVIDFKRDKQGIPATVASIEYDPNRTAFIALLNYQDGEKRYIIAQNGLQVDQNVVSSNEAATPEIGNAMPLANIPLGTVISCIELRPGQGAVMARSAGAFAQLLAREGKYATIKLPSGEIRRVLALCMATIGAVSNSDHQLMIGGKAGRSRWLGIRPRTRPVAMNPVDHPMGGGEGRASGGHPRSRKGLPAKGFKTRSRTKASNKYIVERRKTRKKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RL17_FERNB
Sequence: MRHRMKRNKLNRYGSHRRSLMRNLAKEIIEHGTIMTTTVKAKVGKEYIEKLITKAVKAYKIKDENKEESIALRRQLFAELGDRKLVNKLVDEIAPKYTGRNGGYTRVIKVGQRRGDGAEVSVLQIVE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RSXE_ECO55
Sequence: MSEIKDVIVQGLWKNNSALVQLLGLCPLLAVTSTATNALGLGLATTLVLTLTNLTISTLRHWTPAEIRIPIYVMIIASVVSAVQMLINAYAFGLYQSLGIFIPLIVTNCIVVGRAEAFAAKKGPALSALDGFSIGMGATCAMFVLGSLREIIGNGTLFDGADALLGSWAKVLRVEIFHTDSPFLLAMLPPGAFIGLGLMLAGKYLIDERMKKRRTEAAAERALPNGETGNV
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit E, Rsx electron transport complex subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NXB4_CERLA
Sequence: ASATWGAAYPACENNCRKKYDLCIRCQGKWAGKRGKCAAHCIIQKNNCKGKCKKE
What is the function of this protein?
This toxin increases the excitability of nerves by delaying the inactivation of the voltage-gated sodium channel (Nav).  Only acts on some crustacean.  Is more abundant, but 15-fold less toxic than neurotoxin B-II.
What are the official names of this protein?
Neurotoxin B-IV.
What is the protein family that this protein belongs to?
Belongs to the worm B-toxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GANA_ASPAC
Sequence: MFASLLLAALPLLTHAALTYRGADISSLLLLEDEGYSYKNLNGQTQALETILADAGINSIRQRVWVNPSDGSYDLDYNLELAKRVKAAGMSLYLDLHLSDTWADPSDQTTPSGWSTTDLGTLKWQLYNYTLEVCNTFAENDIDIEIISIGNEIRAGLLWPLGETSSYSNIGALLHSGAWGVKDSNLATTPKIMIHLDDGWSWDQQNYFYETVLATGELLSTDFDYFGVSYYPFYSASATLASLKTSLANLQSTYDKPVVVVETNWPVSCPNPAYAFPSDLSSIPFSVAGQQEFLEKLAAVVEATTDGLGVYYWEPAWIGNAGLGSSCADNLMVDYTTDEVYESIETLGEL
What are the official names of this protein?
Arabinogalactan endo-beta-1,4-galactanase, Endo-1,4-beta-galactanase, Galactanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 53 family.
Protein: CWC2_USTMA
Sequence: MSETQAQGVQSPGQVASTSYQPRPARKQVTQAKFDAIREAFSARPDSAGTFNIWYENFAGVDREENEAQKAKRETRCDIARDSGYTRADITLKTQAARIQQGAPVAPDEAVYCCIHFARGCCPHGAECNFLHRLPRPNDYPSQGRDCFGREKLGNYKDDMSGTGSLSKVNRTLYVGRIHEEHGVSSPSAPANSAWRDGGKTLKGGRSIHDVRNKNGPRPRQDPKSYRPQHNSVRPETDNATERVVRRHFSEWGEIDRLRVLTGRSCAFVTFKYEANAQFAKEAMLNQSLDHNEIINVRWASDDPNPAAQKRNQEQMRRAGERAIMAGMSEQAIQAQQALRALEGLEHQRGEDADSKRRRISHQSYDEDMRRLEEENERGWVEFAQERQAAVAAAPTSQAPSAASSASKNNITGSLLNSETMSHLASLQNLDQKQGGASDTYPPPVSSNGLGSLAGYGSDSEDDDS
What is the function of this protein?
Involved in the first step of pre-mRNA splicing.  Required for cell growth and cell cycle control.  Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex.  May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA.  Associates predominantly with U6 snRNAs in assembled active spliceosomes.  Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing factor CWC2.
What is the protein family that this protein belongs to?
Belongs to the RRM CWC2 family.
What are the subcellular locations of this protein?
Nucleus.