PharMolix/UniProtQA huggingface dataset:
Protein: DRMH3_ARATH
Sequence: MGLLDHLWDDTVAGPRPENGLGKLRKHHTFSFRPSSGNDQSEAGSARSYGEDSLPEEAVKVTRSIMIIKPPGYQGSSAPASPAGSTPPLSPFSPPLSPFSGGKEPFRFRRRSTSDAFEKAAGGSETGPRSSPPTYGM
What are the official names of this protein?
Dormancy-associated protein homolog 3, DRM1 homolog 3.
What is the protein family that this protein belongs to?
Belongs to the DRM1/ARP family.
Protein: FOLD_RHIL3
Sequence: MTTVIDGKNVAASVIQTVKSATAALEKSSGVTTGLAVVIVGDDPASHAYVGSKGRMAKECGFKSVQHTLPADTKQEDLAALVAALNADPSIHGILVQLPLPKPLDSEAIIQSILPEKDVDGLSVVNAGKLATGDLKTGLVSCTPAGAMVFVRRTHGEDLSGLNAVVIGRSNLFGKPMAQLLLNANATVTIAHSRTKNLAEVCRNADILVAAVGRPEMVRADWVKPGATVIDVGINRVAAPETGEGKTRLVGDVAFEEVSAVASTITPVPGGVGPMTIAMLMANTVIAAHRTAGQTPPQF
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: YOHO_SALPK
Sequence: MRVAKIGVIALFLLMAIGGIGGVMLAGYSFILRAG
What are the official names of this protein?
UPF0387 membrane protein YohO.
What is the protein family that this protein belongs to?
Belongs to the UPF0387 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: UBX2B_XENLA
Sequence: MEERENSEEGDDGAGEEEEEDQGSGEDGGEVGAEREQEAELKDSLRPSVLDLQLALARLCEDEYQDQPSKMPVLGLQIKDHQFERSFSGNGKVPSPGKIVNELFKEAKEHGAIPIDDTSKSSGAFYRARTFTGRGYKLGDSSKREFEYMQGEDPFEQGQEIQILLKLWSNGFSLDDGELRSYSDPINAEFLESVKKGEIPVELQRLVHGGQVNLDMEDHQDQEYIKPRLKFKAFSGEGKKLGSVTPEIISTPSSPEEEHKRFLNAEVDLDEHVPTTKIQIRLADGTRLIQRFNLSHRIMDVRQFIIHARSDFAQCDFALLTTFPNVELTDETQTLEEADILNTVILQRLK
What is the function of this protein?
Adapter protein required for Golgi and endoplasmic reticulum biogenesis.  Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis.  Regulates the centrosomal levels of kinase aurka-a/Aurora A during mitotic progression by promoting aurka-a removal from centrosomes in prophase.  Also, regulates spindle orientation during mitosis.
What are the official names of this protein?
UBX domain-containing protein 2B, NSFL1 cofactor p37, p97 cofactor p37.
What is the protein family that this protein belongs to?
Belongs to the NSFL1C family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Endoplasmic reticulum. Golgi apparatus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes to centrosome during mitotic prophase and metaphase.
Protein: RL27_CORGL
Sequence: MAHKKGASSSSNGRDSEAKRLGVKRFGGQQVSAGEILVRQRGTKFHPGENVGRGGDDTLFALKTGAVQFSTKRNRRLVNIVETEAVDA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: GVPA_CERS4
Sequence: MAIEKSVASASIAEVIDRILDKGVVIDAFVRVSLVGIELIAIEVRAVVASIETWLKYAEAVGLTVDPATT
What is the function of this protein?
Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms.  They allow the positioning of the organism at the favorable depth for growth.  GvpA type proteins form the essential core of the structure.
What are the official names of this protein?
Gas vesicle structural protein, GVP.
What is the protein family that this protein belongs to?
Belongs to the gas vesicle protein type A family.
What are the subcellular locations of this protein?
Vacuole, gas vesicle membrane.
Protein: NRDR_HALLT
Sequence: MNCPDCGDEQTRVIDTETSADGTSVRRRRECQRCSFRFTTYERPEWDSLQVKKRNGTIEPFNRTKLRAGIERAVEKRDVSETTVTTLVDDIESALQDRETRLVSSSLIGELVSDRLRDLDKVAYIRFVSVYKAFSEPQEFLRELDAVLNAEIDDFEAPNDSQ
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: GPDA_VESOH
Sequence: MSNNLSIIGAGAWGSALSIALYDNFDTIYLHTHTQADIKKLKSKHSALSIPYPYNVKIAYDLYKLQDSKNIIITTPSYAFSEILEKIKPFINHTHKIAWGTKGFDTTKRCFLYESFKRLFPNRNGCVISGPSFAFEVALNKPTALVVASIDENTRNHFAKLIQTNTLRTYTNADIIGVEVGGSVKNILAIAAGIASGLKYGFNTQAALIARGLSEMSRLGKSLGAKNSTFIGLSGLGDLVLTCSDNLSRNRRFGQELVNNHNIKNALINVGGTVEGLNTLDLILSIANKKQVEMPICEQVYQITQGKITPAEAVNYLMSREQQQNNE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VAPC1_MYCBO
Sequence: MIVDTSAIIAILRDEDDAAAYADALANADVRRLSAASYLECGIVLDSQRDPVISRALDELIEEAEFVVEPVTERQARLARAAYADFGRGSGHPAGLNFGDCLSYALAIDRREPLLWKGNDFGHTGVQRALDRR
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.
What are the official names of this protein?
VapC ribonuclease Mb0625, RNase Mb0625, Toxin Mb0625.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: Y1534_ARATH
Sequence: MSLNRFLFTSFSFFLFFIVHFASSATLPTQEGEAFKVVLTTLKKTNIDLNVDPCEVSSTGNEWSTISRNLKRENLQGSLPKELVGLPLLQEIDLSRNYLNGSIPPEWGVLPLVNIWLLGNRLTGPIPKEFGNITTLTSLVLEANQLSGELPLELGNLPNIQQMILSSNNFNGEIPSTFAKLTTLRDFRVSDNQLSGTIPDFIQKWTKLERLFIQASGLVGPIPIAIASLVELKDLRISDLNGPESPFPQLRNIKKMETLILRNCNLTGDLPDYLGKITSFKFLDLSFNKLSGAIPNTYINLRDGGYIYFTGNMLNGSVPDWMVNKGYKIDLSYNNFSVDPTNAVCKYNNVLSCMRNYQCPKTFNALHINCGGDEMSINGTIYESDKYDRLESWYESRNGWFSNNVGVFVDDKHVPERVTIESNSSELNVVDFGLYTQARISAISLTYYALCLENGNYNVNLHFAEIMFNGNNNYQSLGRRFFDIYIQRKLEVKDFNIAKEAKDVGNVVIKTFPVEIKDGKLEIRLYWAGRGTTVIPKERVYGPLISAISVDSSVNPSPRNGMSTGTLHTLVVILSIFIVFLVFGTLWKKGYLRSKSQMEKDFKSLELMIASFSLRQIKIATNNFDSANRIGEGGFGPVYKGKLFDGTIIAVKQLSTGSKQGNREFLNEIGMISALHHPNLVKLYGCCVEGGQLLLVYEFVENNSLARALFGPQETQLRLDWPTRRKICIGVARGLAYLHEESRLKIVHRDIKATNVLLDKQLNPKISDFGLAKLDEEDSTHISTRIAGTFGYMAPEYAMRGHLTDKADVYSFGIVALEIVHGRSNKIERSKNNTFYLIDWVEVLREKNNLLELVDPRLGSEYNREEAMTMIQIAIMCTSSEPCERPSMSEVVKMLEGKKMVEVEKLEEASVHRETKRLENMNTMKKYYEMIGQEISTSMSMIMSDRSESSADH
What are the official names of this protein?
Probable LRR receptor-like serine/threonine-protein kinase At1g53420.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: DPRE2_MYCS2
Sequence: MVFDAVGNPQTILLLGGTSEIGLAICERYLRNASARIVLAVMPGDPGRDAAVEQMRKAGASAVDVVDFDALDTESHPAVIDQAFAGGDVDVAIVAFGLLGDAEELWQNQRKAVQIAGVNYTAAVSVGVLLGEKMRAQGSGQIIAMSSAAGERVRRSNFVYGSTKAGLDGFYLGLGEALREFGVRVLVIRPGQVRTRMSAHVKEAPLTVDKEYVAELAVTASAKGKELVWAPGAFRYVMMVLRHIPRPIFRKLPI
What is the function of this protein?
Component of the DprE1-DprE2 complex that catalyzes the 2-step epimerization of decaprenyl-phospho-ribose (DPR) to decaprenyl-phospho-arabinose (DPA), a key precursor that serves as the arabinose donor required for the synthesis of cell-wall arabinans.  DprE1 catalyzes the first step of epimerization, namely FAD-dependent oxidation of the C2' hydroxyl of DPR to yield the keto intermediate decaprenyl-phospho-2'-keto-D-arabinose (DPX) (PubMed:22188377).  The intermediate DPX is then transferred to DprE2 subunit of the epimerase complex, most probably through a 'substrate channel' at the interface of DprE1-DprE2 complex (By similarity).  DprE2 then catalyzes the second step of epimerization, the NAD(+)-dependent reduction of DPX that leads to the formation of DPA (PubMed:22188377).
What are the official names of this protein?
Decaprenylphosphoryl-2-keto-beta-D-erythro-pentose reductase, Decaprenyl-phospho-2'-keto-D-arabinose reductase, Decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose 2-reductase, Decaprenylphosphoryl-beta-D-ribofuranose 2'-epimerase subunit DprE2, Decaprenyl-phosphoribose 2'-epimerase subunit 2, NAD-dependent decaprenylphosphoryl-D-2'-keto erythropentose reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Periplasm.
Protein: LRC73_RAT
Sequence: MLPSSIQISGEPLSGAEVRDICRGLRDNAVRLLSLRGCRLCDRDFGRICRALAGATSLAQLNLNLGVVSSPSRIKQLAEALRTNRSIQSLFLHGSPLTDAGLALLNPALALHPALVALDLGDCMLGDEAINLICGLLPPDGAKSGLKELTLSANPGITPKGWSRLAIAVAHSSQVRVLNLDYNPLGDHVAGMLAVAVASSRTLEVLDLEGTGLTNQSAQTLLDMVENYPTALRSLVLAENSISPELQQQICDLLSEGEEEEEMAGGAADTQEWGRGREPAAHQRGGSSWKCPSDPNSQMVLMTSGLGDSLLAETEM
What are the official names of this protein?
Leucine-rich repeat-containing protein 73, NOD3-like protein.
Protein: RNH_IDILO
Sequence: MSNSKTVHLYTDGSCLGNPGPGGYGAVLEYGKHHKELSQGYRLTTNNRMEMLATIAGLRELKRSCHVILTTDSQYVKQGVEQWMHRWKQNGWRTSARKAVKNKDLWQQLDEEVNRHKVEWKWIKGHSGHKQNERCDELARDAATREPMLEDEGFGGE
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M1IP1_MOUSE
Sequence: MMQICDTYNQKHSLFNAMNRFIGAVNNMDQTVMVPSLLRDVPLSEPEIDEVSVEVGGSGGCLEERTTPAPSPGSANESFFAPSRDMYSHYVLLKSIRNDIEWGVLHQPSSPPAGSEESTWKPKDILVGLSHLESADAGEEDLEQQFHYHLRGLHTVLSKLTRKANILTNRYKQEIGFSNWGH
What is the function of this protein?
Plays a role in the regulation of lipogenesis in liver.  Up-regulates ACACA enzyme activity.  Required for efficient lipid biosynthesis, including triacylglycerol, diacylglycerol and phospholipid.  Involved in stabilization of microtubules.
What are the official names of this protein?
Mid1-interacting protein 1, Gastrulation-specific G12-like protein, Mid1-interacting G12-like protein, Protein STRAIT11499 homolog, Spot 14-related protein, S14R, Spot 14-R.
What is the protein family that this protein belongs to?
Belongs to the SPOT14 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Note=Associated with microtubules (PubMed:15070402).
Protein: FATC_VIBA7
Sequence: MTSLNLNFRVSVVLVILLSIAFIFINSGFDLEYIIPRRLIKLSAIIIGGSCVAISAVIFQALARNRILTPSIMGYESIYLVWQALLLLFVGTSGSAVLGVVGNFVVSAVLILLYSFVIQFWVLKRFQHDMHQVLLIGFVLTMVLTTVAQFIQIRISPGEFSIFQGLSYTSFERAKPSTLLFAGTVLSILALFANKWVSELDVIGLGRDQAMSLGLNDAHYIPKYFSVIAILVAISTSLIGPTAFMGVFIANIAYSITGSPQYRHTLPVACTIAIVMFLTAQLMVEHFFNYKTTVSILVNVLCGGYFLIITMRARSQL
What is the function of this protein?
Involved in the uptake of iron in complex with the siderophore anguibactin.  Responsible for the translocation of ferric-anguibactin across the cytoplasmic membrane.
What are the official names of this protein?
Ferric-anguibactin transport system permease protein FatC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DXR_NITHX
Sequence: MGAVPLKNNKPVEAGVRTVTVLGATGSIGDSTMDLLRGAPGRYRVEALTANSNVEALVKLAREFAARFVAVADPARFGELKDALAGSGIECGVGESAIIEAASRPADWLMAAVSGAAGLKPALAAVDRGTTIALANKECLVCAGDFFMQRAAKAGACILPADSEHNALFQALSSGNRDELTRVIITASGGPFRTWAAADIEKATLAQALKHPNWSMGRKITIDSASMMNKGLEVIEAACLFTLTPDEIDVLVHPQSIVHGMVEFSDRSVVAQLGTPDMRTPIAHCLGWPERIVGPAAKLDLASIGQLTFEAPDFTRFPALRLAYDALRTGNGATTVYNAANEIAVAAFIGEKIRFGAIARLVEATMNGWVRAGNLAPLASADDAIAIDHNARNMAASLLPQIAAKAT
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: RUTD_METC4
Sequence: MAAPVHHEVHGPAGGRTVLLSPGLGGSAHYFAPQVPVLAERFRVVTYDHRGTGRSPSPLEPGHDIAAMARDVLALLDHLGIGTADIVGHALGGLIALQLALTHPERVGRIVVINGWAAMDPATRRCFAARKALLRHAGPEAFVRAQAIFLYPAPWLSENAARVAADEAQALAHFPGTRTALARITALETFDATAALGRIPHETLLMAARDDVLVPFTASDVLAAGLPNARLDLAPEGGHAHSVTRPEAFNRTLLDFLASP
What is the function of this protein?
Involved in pyrimidine catabolism.  May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.
What are the official names of this protein?
Putative carbamate hydrolase RutD, Aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
Protein: SEC6_SCHPO
Sequence: MTAAASDDAVYNKVADILRQCEDFHRLSTHIERFEREQASLNMHVKTELEKHVEAVELGKLALHDAQTKRVKLLQELHNMLTLCESAREMVDEFPLISRMSRIYKNCYATKQMISQLNNLVKETDVIEDMLREDLELDSDMPNLLRAHYKLSKLREFREEALYQASLEGQSDLPITLENSFSNLNTLSDNFDRLVLNFCRNIFQLVKSGHIKTIVQIFKIVEAEESSDEVLKSIRDAKSSLPDSQDGPFLSLQGMTRQLRNFRLRVLEEFQGAAAENFQRAWVSYLEDGSGELNLDFIFEDLKVAFYVLPDLTPPSYNIAKTFASIYQECLVGLVTKAVSLDTPAAVYLYLINFHREYRKFFEENAPFSVDEVEPGLEDGKDGILVREYTRLFTQKIREWSDKLFQSSVDTFMKRESEPELDSDGNYGLQGTIIFFQMITQQINIISHTNNSDVVGIVLSSIMYIMQSMQDQWKSVMRSELSQQLSGNPESVPPGLMEYLLAVANDNLKCAGFMDNTLLNTFELITSEREEDLREAFGKTVDGYILISDIGVSQIVAIISNDVKPALTSLFQPNWYQSSNMKLIVDTFRDYIVDCIEHMVPGLFDVFLLEASNALTISYLRSIFNKNACFDGDNAIQQIRSDIALAIRVFGEYMAAEHLRSTFEPIEKLLLGMLDADVETVSEYFHLLKEAYWDAPLSLVEAVLQNRTDLEKSIIKKMIDIVRHENDSLQIDTSQQPTVFSQVTSLSGSSIL
What is the function of this protein?
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
What are the official names of this protein?
Exocyst complex component sec6.
What is the protein family that this protein belongs to?
Belongs to the SEC6 family.
What are the subcellular locations of this protein?
Nucleus. Cell septum. Cell tip. Cytoplasm, cytoskeleton, spindle pole.
Protein: VES_SHIDS
Sequence: MEYFDMRKMSVNLWRNAAGETREICTFPPAKRDFYWRASIVSIAANGEFSLFPGMERIVTLLEGGEMFLESTDRFNHTLVMLPISRTCVFQ
What are the official names of this protein?
Putative protein Ves.
What is the protein family that this protein belongs to?
Belongs to the Ves family.
Protein: YRU4_CAEEL
Sequence: MEHPKRPTPKNEALHIDASGRGESSFSVHRSHSGGHEPFAPSPGSSIGASVSMFSSRNSEAEVGDAEDLDGVRTIMMNIGVPDLLADREIQMRYPEFYQFLLAEQPTWFEPAPSNGTVYRVHHTTPLPDNHKKLRKELPFEMLDLMYRFFRQKHVNSQRKRENKELLEANKQLRIAAVQMFTKAEQEEEYISNSLLKKIQQLNQDKDYLVKKYQKDEESLTKSLMANVAKIPDVHGDEAAAEKLMADKQAEIERLRTYCSRAEKSYQEELMRLRAEKVDHESALEQEQELLINTLGKRMSQMNEEKRKLQQALEMAYLNGFVDFDDTVEVALHASASQKYNGNSPNVSANSPVVNTNSPAVSTSSPLVRNTDQQSTSSYRQQLNETAHLHIENKKLVGMCNQERRRSQATEAEVKKLNQRMSKMEAVLEAIRIEAVRTDGPLAWRLAALSHDNSIDEPPHRMLAERRAHGSSPPTVVVQPSTSRAGSNSTANINNDTHPHAQVAPILATVHPTQRATPARNERPDSHY
What are the official names of this protein?
Uncharacterized protein T09B9.4.
Protein: CC137_HUMAN
Sequence: MAGAGRGAAVSRVQAGPGSPRRARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGEVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQAYRALKQRQQQLHGERPHLTSRKKPEPQL
What are the official names of this protein?
Coiled-coil domain-containing protein 137.
What are the subcellular locations of this protein?
Chromosome.
Protein: RS13_MYCGE
Sequence: MARILGIDIPNQKRIEIALTYIFGIGLSSAKTILKKAKINPDKRVKDLSEEELVAIRNAASGYKIEGDLRREIALNIKHLTEIGSWKGIRHRKNLPVRGQRTRTNARTRKGPRKTVANKKIESK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: YJHD_ECOLI
Sequence: MNCETKQRTQFECIYFSQYWAKGDFIAKRAPIGQWEPYSEESLLGIIVTSVCRIKVAMLKPEPPRDPHIPLMGDFN
What are the official names of this protein?
Putative uncharacterized protein YjhD.
Protein: ESXA_STAAM
Sequence: MAMIKMSPEEIRAKSQSYGQGSDQIRQILSDLTRAQGEIAANWEGQAFSRFEEQFQQLSPKVEKFAQLLEEIKQQLNSTADAVQEQDQQLSNNFGLQ
What is the function of this protein?
Virulence factor that is important for the establishment of infection in the host.  EsxA is required for EsxB synthesis as well as secretion (By similarity).  Modulates host cell apoptotic pathways and mediates together with EsxB the release of S. aureus from the host cell.  By acting on apoptosis, plays a role in the modulation of dendritic cell-mediated immunity (By similarity).
What are the official names of this protein?
Type VII secretion system extracellular protein A, Ess extracellular protein A.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. sagExaA-like subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the ESAT-6 secretion system (Ess) / type VII secretion system (T7SS).
Protein: LPXD2_KORVE
Sequence: MSATLQKLAELTGSSLIGDSTLTICSVANLNHATPRDLVFCEDEKYLGDAFASPAAAIVVGEFAASAHDAPKPLLISTQPRLAFAKAAKVLRSHKKRSGGIVHPTAVVPPTVVFGAEVVVGAYVVLGEHVHIGDRVCIGAGVCIGSDVKIGTDCEIHSRVTIYHGTHIGNHVIIHAGAVLGSDGFGYVRDKLTGRYHQMPQIGHLIVGDHVDIGANVTIDRGGLEDTVIGAGTKLDNLVHIGHNVRIGENVVIAAQTGISGSCTIGAGSIIGGQVGMGDHATLEEGTILGGQSGILSEKIFREKGPCFGTPAKPLKQYLREQAALSRLSRRSE
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: BSHC_BACCN
Sequence: MEIKEISVPLQGVVGDYIKSDNKIQTCFDYALTEAGFKQRLYDLRNRKFFRQELVEHLLEYNKQLQAGQSTIQNIEALADENTYVVIGGQQAGLLTGPLYTVHKVISIVQLAKEKEASLGTRVVPVFWIAGEDHDVDEINHTFVTKNKKIKKMIFHDRHSKKTSASESEISIEDCSKWIEEIFKTYPETNFTKDVLQFIQEALEESSTYVDFFARLITKLFADTGLILVDSHHPNLRKLEVSFFKRIISQYKEVQEALHNQQQIVKEYGYKPIIETKQNAIHVFMQIDEERVLLEEENGKFVGKSGIYSFSYEELIEEMEQSPERFSNNVVTRPLMQEYLFPTVAFIGGPGEIAYWSELQQVFHVFDFQMPPVVPRLTISYMERDIITDLYDLNLQEEDPFVKDLDKLREKWLSNQVEEPVEEKFQEAKKNMMDIHSSLQQFVNRIDPGLKEFAGKNERKIQEQIELLERMLKQNLERRHEVELNKFRRLQYALRPLGAPQERVWNVCYYLNQYGLDFVERVTKQSYSWNGTHHVIKL
What is the function of this protein?
Involved in bacillithiol (BSH) biosynthesis.  May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.
What are the official names of this protein?
Putative cysteine ligase BshC.
What is the protein family that this protein belongs to?
Belongs to the BshC family.
Protein: Y9358_DICDI
Sequence: MNDNNDNNNNNKNIDNVDDDNDDNDKGKYKGNEFSILEKSLNKLLNNVETFKNYNNQMIESNNKTVDFVHSRFNK
What are the official names of this protein?
Uncharacterized protein DDB_G0267542.
Protein: MURG_METS4
Sequence: MTVAQPLVLLAAGGTGGHLFPAEALALRLRDRGIRVVLASDGRVEALSGGFPASEIVSIPSATPSGRSPLARGAAFLTLGRGFAAAIRAVRRLNPAVVVGFGGYPTVPPLLAAQMLRVPTLLHEQNAVMGRANGFLARGASVIATGFSEVRGVPARAGARRVHTGNPVRPAVLAAADTPYPALSPDGPLNLLAFGGSQGARVMSEVVPEAVARLPAPLRARLHVVQQARAEDLARAEAIYGRAGLASASVAPFFKDLPARMAAAHLVVARSGASTVAELAVIGRPAILVPLPGSLDQDQAANAAVLGAAGAAFPRPQTDFIPERLAADLEALFGAPERLAAAAAAARRTGIPDAAERLAALVVETAIAASTR
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GCH1_BACC7
Sequence: MAKVNLEQIEHAVRLILEAIGDDPNREGVLDTPKRVAKMYAEVFSGMHEDPKEHLHKVFGEDHEELVLVKDIPFYSMCEHHLVPFYGVAHVAYIPQGGKVTGLSKLARTVDTIARRPQLQERITSTVANSIMEVLEPHGVMVVVEAEHMCMTMRGVKKPGAKTVTTAVRGVLENDAAARSEILSFIKTK
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: DUSP_MYXVL
Sequence: MDKKSLYENVLLKSTGALPKARVPTKMMRVTDYVYLGNYNDAKAAPTSGIGFKYILNLTTEKYTIKNSSITIIHMPLVDDEYTDLTKYFDYATTFLSNCEDKHYPVLVHCMAGVNRSGAIIMAYLMSRKSKDIPAFMYFLYIYHSIREQRGAFLENPSFRRQIIEKYIINEHKLKLFG
What is the function of this protein?
Serine/Tyrosine phosphatase which down-regulates cellular antiviral response by dephosphorylating activated STAT1 and blocking interferon (IFN)-stimulated innate immune responses.
What are the official names of this protein?
Probable dual specificity protein phosphatase H1 homolog.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Approximately 200 molecules of H1 are packaged within the virion and are essential for the viability of the virus.
Protein: MURG_STRPG
Sequence: MPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEHTEIEKSGLDVTFHAIATGKLRRYFSWQNLADVFKVALGLLQSLFIVAKLRPQALFSKGGFVSVPPVVAAKLLGKPVFIHESDRSMGLANKIAYKFATTVYTTFEQEDQLSKVKHLGAVTKVFKDANQIPESTQLEAVKEYFSRDLKTLLFIGGSAGAHVFNQFISDHPELKQRYNIINITGDPHLNELSSHLYRVDYVTDLYQPLMAMADLVVTRGGSNTLFELLAMAKLHLIVPLGKEASRGDQLENATYFEKRGYAKQLQEPDLTLHNFDQAMADLFEHQADYEATMLATKEIQSPDFFYDLLRADISSAIKEK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TRMD_AYWBP
Sequence: MIIEIITIFPSFFKSFCETSIIKRALEQKKVQIKIHDLRIYSSNKHNQVDDSVYGGGVGMLLSFPPFFDCLQKIKTPQSKVILLSPQGQIFNQIHATNFAQKETHLIILCGNYEGVDARILQYIDAEISIGDYVLTGGEIAATVLVDAITRLIPGVIKEQSYLEDSHQQGLLKYPQYTRPQNYFNHVVPTILLSGNHAKIRSWRQKESLKKTLQKRPDLLENKKLTLEQTKLLKEIKQELQK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPGG_PSESM
Sequence: MIVSPCDAPKTPVKRLRSALLASSALVCLFSAGQLWAFSLDDVAAKAKEMAGQKFEAPRSNLPNELRDMKFADYQKIRFRDDKAEWAGDKTPFKVSFYHQGMHFDTPVKINEVTATSVDEIKYDASRFDFGGLNIDPKTSEKLGYAGFRVLYPINKDDKQDEIMTMLGASYFRVIGKGQVYGLSARGMAIDTASPSGEEFPRFKEFWIEKPGPDDNHLVIFALLDSPRATGAYQLTLRPGTNTLVDVKSRMFLRDKVNKLGVAPLTSMFLFGANQPSRVPNYRRELHDSSGLSIQAANGEWLWRPLNNPKHLSISSFSVENPRGFGLLQRGRDFSQYEDLDDRYDKRPSAWIEPKGDWGKGTVELVEIPTADETNDNIVAFWKPETLKAPGEEMAFDYRLHWTMQENSIHSPDLGWVKQTQRSIGDVRQSNLIRQPDGSLAFLVDFVGPVLAALPEDKTIRSQVTTDDNVELVENNLRYNPVTKGYRLTLRVKVKDAGKATEMRAYLLREIPAEPGKEPALLVADKADEKKAAAKEAAAKEAAKPAVAKESANDQVEIAKADAPKPEAAKPEAGKADASKADAAKGDVAKADAAKADDVAKGKDGKDIQQPATEAAPTHPEPAKTLQVMTETWSYQLPSDE
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein G.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.