PharMolix/UniProtQA huggingface dataset:
Protein: RICE1_ARATH
Sequence: MASFDGQGFMMVDNSWVQTKAIDVESTTDISPYLSKILEDSVWNGNRSIVFDVYWDVKSVSTKSEWRLCSVKFSTKNFCLFLRLPNPFCDNLKDLYRFFASKFVTFVGVQIQEDLALLKENHGIVIRSSLEIGKLAAKARGTPIVEFLGTRELAHKILWYDMSRLDSIQSKWDEASSNDRLEAAAIEGWLIFNVYDQLQQ
What is the function of this protein?
3'-to-5' exoribonuclease (RNase) specifically targeting single-stranded RNAs (PubMed:28463111).  Triggers miRNA accumulation in RNA-induced silencing complex (RISC), composed of miRNAs and AGO proteins, by degrading uridylated cleavage fragments (PubMed:28463111).  Required during plant growth and development (PubMed:28463111).
What are the official names of this protein?
Protein RISC-INTERACTING CLEARING 3'-5' EXORIBONUCLEASE 1.
What is the protein family that this protein belongs to?
Belongs to the RICE family.
Protein: YBHP_ECOL6
Sequence: MPDQTQQFSFKVLTINIHKGFTAFNRRFILPELRDAVRTVSADIVCLQEVMGAHEVHPLHVENWPDTSHYEFLADTMWSDFAYGRNAVYPEGHHGNAVLSRYPIEHYENRDVSVDGAEKRGVLYCRIVPPMTGKAIHVMCVHLGLREAHRQAQLAMLAEWVNELPDGEPVLVAGDFNDWRQKANHPLKVQAGLDEIFTRAHGRPARTFPVQFPLLRLDRIYVKNASASAPTALPLRTWRHLSDHAPLSAEIHL
What are the official names of this protein?
Uncharacterized protein YbhP.
Protein: FRDD_SHIFL
Sequence: MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPLGLFPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFYGLAAILTVVTLIGVVTI
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Fumarate reductase 13 kDa hydrophobic protein, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CHIP_BETVU
Sequence: MTLLLKNTLYLALIISVISSFPTSLFAQNCGCAPNLCCSNFGFCGTGTPYCGVGNCQSGPCEGGTPTTPTTPTTPTTPGTGGGGSSVSDIVSQAFFDGIIGQAAASCPGKNFYTRAAFLSAVDPKFGNEGSSDDNKREIAAFFAHISHETTNLCHIEERDGDVGDAYCDQDKAAQYPCAAGKKYYGRGPLQLSWNYNYALAGQAIGFDGLGNPEKVATDVNTSFKAAMWFWMTNVHSVMNQGFGATTKAINGALECNGQNQDQANDRIQFYKKYCADFGVAPGDNLTC
What is the function of this protein?
Defense against chitin-containing fungal pathogens.
What are the official names of this protein?
Acidic endochitinase SP2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family. Chitinase class I subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: SAP9_ARATH
Sequence: MGSEQNDSTSFTQSQASEPKLCVKGCGFFGSPSNMDLCSKCYRGICAEEAQTAVAKAAVEKSFKPSPPRSLFIAEPPAVVVEPKPEKAAVVVVSAEPSSSAVPEANEPSRPARTNRCLCCNKKVGIMGFKCKCGSTFCGEHRYPETHDCSFDFKEVGRGEIAKANPVVKADKIQRF
What is the function of this protein?
May be involved in environmental stress response.
What are the official names of this protein?
Zinc finger A20 and AN1 domain-containing stress-associated protein 9, AtSAP9.
Protein: SYY_STRPI
Sequence: MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSLHLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQGQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIETGISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVITVPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDEIEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKELKQGLRGVPNYQVQADEHNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYVLSDADKLENELTVIRRGKKKYFVLTY
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_THETH
Sequence: MRVAFFGTPLWAVPVLDALRKRHQVVLVVSQPDKPQGRGLRPAPSPVARYAEAEGLPLLRPARLREEAFLEALRQAAPEVAVVAAYGKLIPKEALDIPPHGFLNLHPSLLPKYRGAAPVQRALLAGERETGVSIMRLDEGLDTGPLYAVWRTPILPDEDAVALGNRLRDKGVELLLEVLERLPELTPRPQEGEVSYAPPLSKEEGRLDFGESAEALYRRHRAVQPWPGSYFFHRGRRVKALRLRPEPGEGEPGVVARVGPEGVAVGTASGLLLLLEVQPEGRRAMPAADWARGYGVAPGTRLGQV
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: YB50_METTW
Sequence: MLRDTLKKAEKARDKKALYGEDIDLERFIKEEAGEHEEVPRAREVPKKVQETLLKVGVDPEERERAGTFIQVDQSGICTTCASESIEIMGMNVALDRYSWLKDYMWKAVAVDTDKYTATTALREAEGEMGGYFIRSMPGSREVFPLQACMFIGDENVMQTAHNIIIAEENSELHIITGCATGQDVSSALHVGVSEFYLKKGAKITFTMVHNWAEQVEVRPRTGIMVGDDATYISNYILTSPVKSIQSYPTAYCTGENSRVVFQSILGGQKDSVLDMGSRVILEGRGSSAEMVSRAVSKDASQIYSRGHLAGRVPEVKGHLECHGLVLSDDSMIYAVPELEGSATELEMSHEAAVGKIAEEEVMYLTSRGLTEDEAASMIVRGFLSMDITGLPPELAAETKRMLDMSLKGM
What are the official names of this protein?
UPF0051 protein MTH1150 homolog, ORF2.
What is the protein family that this protein belongs to?
Belongs to the UPF0051 (ycf24) family.
Protein: SYC_ANASK
Sequence: MSIQVHDTLTAQKRELVPLEPGKLRLYVCGPTVYDYSHLGHARCYVVWDVVVRHLRARGLEVRFVRNFTDVDDKIIQRANERGEDPIALASRFADAFHEDMDALGNLRPDVEPRVSGHIPEIVALIARLVERGFAYAPGNGDVYYAVRKFPEYGRLSKRNLDDLIAGARVEPGEAKRDPLDFALWKAAKPGEPAWESPWGKGRPGWHIECSAMTQKHLGAPIDLHAGGKDLVFPHHTNEIAQSVAATSDGLHAEDFARYWMHNGFVQIDDEKMSKSLGNFFTIRDVLARFDGEALRFFLLGTHYRRDFNFSDQVLAEAERRLSALYETVEKAERLGAGAAPAAEPAFVERARAALDDDFNTPQVLGIVAEAFTEANALADRKGKKSPEEKARLAAFARGARAVGAVLGILDRPPAQALSAIRDRAAARRGIDGGEVERSIAERAAARAAKDFARSDAIRDALLARGVVLMDGPQGTTWKVE
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBN_POPDE
Sequence: METATLVAISISGLLVSFTGYALYTAFGQPSQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: UREG_ALIFM
Sequence: MQDYKQPLRIGVGGPVGSGKTALLEVLCKTLRDTYQIAVVTNDIYTQEDAKILTQAEALAADRIIGVETGGCPHTAIREDASMNLAAVEELAQRHKNLDVVFVESGGDNLSATFSPELADLTIYVIDVAEGEKIPRKGGPGITKSDLLIINKIDLAPYVGASLEVMESDTARMRPTRPYVFANLKEGVGLDKIIEFIVDRGMLDAK
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRAM2_ARATH
Sequence: MENDVKENLEEEEDRLLPPPPPSQSLPSTDSESEAAFETNEKILIVDFESPDDPTTGDTPPPFSWRKLWLFTGPGFLMSIAFLDPGNLEGDLQAGAIAGYSLLWLLMWATAMGLLIQMLSARVGVATGRHLAELCRDEYPTWARYVLWSMAELALIGADIQEVIGSAIAIQILSRGFLPLWAGVVITASDCFLFLFLENYGVRKLEAVFAVLIATMGLSFAWMFGETKPSGKELMIGILLPRLSSKTIRQAVGVVGCVIMPHNVFLHSALVQSRKIDPKRKSRVQEALNYYLIESSVALFISFMINLFVTTVFAKGFYGTEKANNIGLVNAGQYLQEKFGGGLLPILYIWGIGLLAAGQSSTITGTYAGQFIMGGFLNLRLKKWMRAVITRSCAIVPTMIVAIVFNTSEASLDVLNEWLNVLQSVQIPFALLPLLTLVSKEEIMGDFKIGPILQRIAWTVAALVMIINGYLLLDFFVSEVDGFLFGVTVCVWTTAYIAFIVYLISHSNFFPSPWSSSSIELPKRVSVSNS
What is the function of this protein?
Seems to be involved in iron uptake.
What are the official names of this protein?
Metal transporter Nramp2, AtNramp2.
What is the protein family that this protein belongs to?
Belongs to the NRAMP (TC 2.A.55) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DEF_STRPG
Sequence: MSAQDKLIKPSHLITMDDIIREGNPTLRAVAKEVSLPLCDEDILLGEKMMQFLKHSQDPVMAEKLGLRAGVGLAAPQIDVSKRIIAVLVPNLPDKEGNPPKEAYSWQEVLYNPKIVSHSVQDAALSDGEGCLSVDRVVEGYVVRHARVTVDYYDKEGQQHRIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFETKEELLILD
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: YEAL_ECO8A
Sequence: MFDVTLLILLGLAALGFISHNTTVAVSILVLIIVRVTPLSTFFPWIEKQGLSIGIIILTIGVMAPIASGTLPPSTLIHSFLNWKSLVAIAVGVIVSWLGGRGVTLMGSQPQLVAGLLVGTVLGVALFRGVPVGPLIAAGLVSLIVGKQ
What are the official names of this protein?
UPF0756 membrane protein YeaL.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: WASC3_DROME
Sequence: MDATAAITGNVDKTQIPPLNQKRILAFVNHFLVSTCTFLNEFALGCETKFVEMERQLQKTEAALIILEAKLASIPTEHHVATEATEAPAISNQQRNEEASMVDTTEPPTTENPTEPELPPESVGVRACEDQRYRKFFKMVQVGVPAPAVKQKMQSEGLEPRILDTPDLILADGQRE
What is the function of this protein?
Acts at least in part as component of the WASH complex which may regulate wash nucleation-promoting factor (NPF) activity and is required for its membrane targeting during endosomal sorting (By similarity).  During embryogenesis, not involved in the wash-dependent developmental migration of hemocytes anteriorly from the tail (PubMed:25739458).
What are the official names of this protein?
WASH complex subunit 3, Coiled-coil domain-containing protein 53 homolog.
What is the protein family that this protein belongs to?
Belongs to the CCDC53 family.
What are the subcellular locations of this protein?
Early endosome.
Protein: Z_GTOVV
Sequence: MGNSKSKSNPSSSSESQKGAPTVTEFRRTAIHSLYGRYNCKCCWFADKNLIKCSDHYLCLRCLNVMLKNSDLCNICWEQLPTCITVPEEPSAPPE
What is the function of this protein?
Plays a crucial role in virion assembly and budding.  Expressed late in the virus life cycle, it acts as an inhibitor of viral transcription and RNA synthesis by interacting with the viral polymerase L.  Presumably recruits the NP encapsidated genome to cellular membranes at budding sites via direct interaction with NP.  Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway.  The budding of the virus progeny occurs after association of protein Z with the viral glycoprotein complex SSP-GP1-GP2 at the cell periphery, step that requires myristoylation of protein Z.  Also selectively represses protein production by associating with host eIF4E.
What are the official names of this protein?
RING finger protein Z, Protein Z, Zinc-binding protein.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae Z protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm, host perinuclear region. Host cell membrane; Lipid-anchor; Cytoplasmic side. Note=Mainly perinuclear. During budding, associates at the inner side of the plasma membrane of infected cells.
Protein: RPOB_HYDCU
Sequence: MTYSLTEKKRIRKDFATRSSILEVPYLLSLQKESFKEFLQKDKKPLERDPIGLHSAFSSVFPIHGVAGTADLEYVSYTMGQPEFDVKECKQRGVTYSSPLRVKMRLVLFDKDAPAGKRPVKDVKEQEVYLGDVPLMTENGTFVINGTERVIVTQLHRSPGVIFDSDKGKSHSSGKVLFNARIIPYRGSWLDFEFDHNDCVFVRIDRRRKLPVSIIFRAMGYSSEEILDTFFDHTHISYKKGAFVMQLVPSQLKGQTAAFDIADGDKVIIKAGKKITARNIKQLQEAKVDSVVVPEEYLLGKVLSSGITNEETGELVARSNEVIASDLIETMKSIKDLSFRILFIDDLENGSYISDTLNLDTTTSQLEAQIEIYRMMRPGEPPTKESSEALFNSLFFDEARYDLSSVGRMKLNRRLGRKDNEGSLVLENQDVVDVVKELLNIRNGLSTIDDIDTLGNRRIRAVGEMAENAFRVGLVRVERAVKERLNQAETDGLLPQDLINAKPVSAAIKEFFGSSQLSQFMDQVNPLSEVTHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINTLAIYAKTNKYGFLETPYRKVIDGQVTEEVEYVSAIDEAQFVIAQASAAMDSDNKLLDELVTARHKNETILASSQDIDYMDVSPKQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLRADKPLVGTGIEKTVAIDSGVTVIALRGGEIVSSDSARIVVRANQEEIAEGETGVDIYNLIKYQRSNQNTCINQKPIVKAGDVVSRGDVLADGPSTDLGELAIGQNMRIAFMPWNGYNFEDSILVSERVVQEDRYTTIHIEELTCLARDTKLGPEEVTSDIPNVGEAALSRLDESGIVYVGAEVKQGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVSKGVEGTVIDVQVFTREGVKKDARALAIQEDELQKVRKDIDEQYKILEEDTIDRIQPMLIGQKLVDGTEITADFLASQDSSKWFGLNVADDALSSHLESLEKQLVAKKEELNGVFEEKKKKLTQGDDLQPGVSKMVKVYVAVKRRIQPGDKMAGRHGNKGVISRICPVEDMPYDETGRPVDICLNPLGVPSRMNVGQILETHLGLAAEGLGAKINAMLEQQADIKELKSFLHKIYNETQGQKVDFDSLTDAEIIELAGNLRKGVPMASPVFDGASEDEIKALLRLADLPESGQMKLYDGISGEEFDRPVTVGYMYYLKLNHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAFTLQEMLTVKSDDLNGRTRMYKNIVDGNEYMEPGIPESFSVLRKEIRALGIDIELEQE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: SSPH2_CLOBL
Sequence: MKSERAKQIIDSKKYIPVYYKNTPVHIEKVDNKENIAHIKSLNTDKEIVVNVKTLSECNKLNN
What are the official names of this protein?
Small, acid-soluble spore protein H 2, SASP H 2.
What is the protein family that this protein belongs to?
Belongs to the SspH family.
What are the subcellular locations of this protein?
Spore core.
Protein: Y13P2_PLAF7
Sequence: MEDKEVVNSENKVEVIKEEENIKKEDDVTKKVSENTEDNDISLANNVSLGKHLLIGSSLKKGISVSVRGRTMNLGMNAKQAGSAWKKKETENVEEEGEEKEKKIDDESFPDLLESTEKMKSELSKEKDKKKKQLKDGKKVEDNVNVFNSGFDRGGKTTDGNSTEFNDKKKYNMYDGNKKNDNAFNKKWYNNQQNDMNNNNQNNQNNMNNNNNNNNGHIFDTNESEEVTGYILPGFKGKHMVGFTCFLKRGTQNPVPPPPAPPLTNNQGENNIPTDNRNNENKKLMNTNIKMNQQVDNNNNNNNNNNNLGSAMNTPMNNMNKGGPRNNVNNSEHMREHSNHTVNRFAPMGQYANSKNNNMNNVHNVNNVNNVNNVNNVNNVNNMNNMNNMNNMNNNMNNMNNNMNNNMNNMNNMNSMNSMNNMNNMNSMNNMNNMNNMNNNNNNKFNENNILYKGTNYNRNVKNLGQNNNEGNTNMKHGHNNNRGQGNNNNNNNNNNFNRRNDKNDNRNFRRKDIDLEINWRNTANPTQEENNNNMNHNNNYNNNNNNNNNNNNNNNNNNNTNHGKNFRNFNNLNNMKNNNSSNNKMMGMNHMQQKGMNSSTGGHKYSFNKNDDQKNNNKMYKNNMGNANNNNNNNAVNTNFNNNNNNGNFHMNNNKSINSMDVKKTRMKDIRNLNDPPKVNNNEA
What are the official names of this protein?
Uncharacterized protein MAL13P1.336.
Protein: TDC_CATRO
Sequence: MGSIDSTNVAMSNSPVGEFKPLEAEEFRKQAHRMVDFIADYYKNVETYPVLSEVEPGYLRKRIPETAPYLPEPLDDIMKDIQKDIIPGMTNWMSPNFYAFFPATVSSAAFLGEMLSTALNSVGFTWVSSPAATELEMIVMDWLAQILKLPKSFMFSGTGGGVIQNTTSESILCTIIAARERALEKLGPDSIGKLVCYGSDQTHTMFPKTCKLAGIYPNNIRLIPTTVETDFGISPQVLRKMVEDDVAAGYVPLFLCATLGTTSTTATDPVDSLSEIANEFGIWIHVDAAYAGSACICPEFRHYLDGIERVDSLSLSPHKWLLAYLDCTCLWVKQPHLLLRALTTNPEYLKNKQSDLDKVVDFKNWQIATGRKFRSLKLWLILRSYGVVNLQSHIRSDVAMGKMFEEWVRSDSRFEIVVPRNFSLVCFRLKPDVSSLHVEEVNKKLLDMLNSTGRVYMTHTIVGGIYMLRLAVGSSLTEEHHVRRVWDLIQKLTDDLLKEA
What is the function of this protein?
Catalyzes the decarboxylation of L-tryptophan to tryptamine and L-5-hydroxytryptophan to serotonin, respectively.
What are the official names of this protein?
Aromatic-L-amino-acid decarboxylase, AADC, DOPA decarboxylase, Tryptophan decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: TRM11_SCHPO
Sequence: MSVYLLHLASTHAHFHLPELETLAKIENVEFWLIPKSEYLNVAFKSDKSRNQALFSHAIKEFQDSISPNDATTQNPFMLAVVNSNEDARRWIRRSIFCKGIYEIYCIGDSFTRLHEKMKELNPAPWDSFKHNSSYKFTFETFGTRRTMKEQLSIISDFEYMQLQGPVSMHNPQHVFTVLENRRNNVEGPKVYFGHWCGSGSRDAIDTFDLKQRSYIGITSFDAELSLVTAQMAMAAPGKLIYDPFVGTGSFLYTCSFFGAHTLGSDIDGRQMRGKNGRSIKSNFRQYKLSPFFLDTFTGDVTNCPLRKNLLLDAIVCDPPYGVRAGAKKIAKCSQRPPKESSSTGNHYPKLEQYQISDMVYDIICFASDRLVDGGRLVLWLPTITEEYGIDDIPSHPYLSLIYNSIQPFTHWSRRLLTFQRLPRAHDSKSLNLLPKINNKTPSHHNFREKYFSSAGRASASTKFSPVLE
What is the function of this protein?
Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.
What are the official names of this protein?
tRNA (guanine(10)-N2)-methyltransferase, tRNA guanosine-2'-O-methyltransferase TRM11, tRNA methylase 11.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM11 methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: T106A_BOVIN
Sequence: MGETFSQLASQKDENKLILPPNPAFGSKAASYSSMGNSRPFFSCVPCERAAGAGFVTCPTCQGSGEIPRELEKQLVALIPYGDQRLKPRHTKLSVFLAVSICLVTSSLIIFFLFPRTIAVQPVGLNSSTVATDEANVYLNITSILNISNNNYCPITVTQLTIEVLHLSLVVGQVSHSLLLHIGPLASEQMFYAVTNRINDENTYKICTWLEIKVHHVLLYIQGTLTYSYLSRSEQLVFQSYEYVDCRGNTSVPHLLVSHPP
What is the function of this protein?
Activates macrophages and polarizes them into M1-like macrophages through the activation of the MAPK and NF-kappaB signaling pathway.  Upon activation, up-regulates the expression of CD80, CD86, CD69 and MHC II on macrophages, and induces the release of pro-inflammatory cytokines such as TNF, IL1B, IL6, CCL2 and nitric oxide (By similarity).  May play a role in inhibition of proliferation and migration (By similarity).
What are the official names of this protein?
Transmembrane protein 106A.
What is the protein family that this protein belongs to?
Belongs to the TMEM106 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ACKA_PARUW
Sequence: MPKVLVMNAGSSSHKLSLFSDKIENAGSALWKAHIEWGKKNPSYTLKNGSQESNPIYLQTTSVKQGIQEVIEKLWIGDFAVIKEVHEIEWIGHRVVHGGSLFHQPVLINASVKKDISNLSSLAPLHNPINLEGIELLEKIFPSIPHFAVFDTAFHRTMREEIKTYPIPYEWKEKGIERYGFHGISHSYCAKQIKKWIKPQETPFKLINCHLGNGASLCAIRDGFSIDTTMGFTPMEGLMMGTRSGSIDPGILIYCLRNKNLSLEELDHLLNFESGLKGIGGTSDMREIHAFKNKQSQLALDMYIYRLKTGIGAMTASLGGIDALCFTGGIGENDSYLRKKTCEELAYLGIQLDLQKNQGGNQDKEISLHDSPVKVFVIHTQEEWMIAKSCLEYLT
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETD_SACOF
Sequence: MGVTKKPDLNDPVLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACNVGLAVLEPSMIGEPADPFATPLEILPEWYFFPVFQILRTVPNKLLGVLLMVSVPTGLLTVPFLENVNKFQNPFRRPVATTVFLIGTAVALWLGIGATLPIDKSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SYE_PROM2
Sequence: MEKRLRLAPSPTGLFHIGTARTALFNWLYAQKIGGKFLLRIEDTDFVRSKSEYTKNILEGLKWLGLKWDDEILKQSDRISIHKSYIKKLLECGAAYRCFTTENEISELREEQKNKGLPPKHDNRHRSLSKEEIDSFISQGKTSVIRFKIDEKIEIKWVDLIRGEIKWQGKDLGGDLVLSRRAKGYEIGDPLYNLAVVVDDNFMNITHVVRGEDHISNTAKQILIYEALNFKLPTFSHTPLILNNEGKKLSKRDCVTSIDEFRDMGYLPEALSNYMAFLGWSPKSTDREILSLNEISEIFDLSDINKAGAKFSWEKLNWINSQYIKNMESIKLSEIIRKYWDDNGWVAPSQEWAHKLAILIRDSMILLKDAIDQSKPFFLIPKIKKEGQDFLENNDSKASLRLILNYLIEQNAIKLNKEKAKEIINEISKMHNVKKGILMKSLRVAFFGSLSGPDLIQSWELFSESKTDISRIERCFKSI
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_PSECP
Sequence: MAAAATGGRATSQPKKTTKGLTPRQKKILETIQRSVNVNGYPPSMREIGDTVGLASLSSVTHQLSQLEKLGYLRRDPKRPRAMEVLMPLTLDGGATGRTARQAAEPAAAAAPGITASVTELPTALDTAMVPLVGRIAAGGPILADQVVEDVMPLPRQLVGQGELFMLKVAGDSMVDAAICDGDWVVVRRQADAANGDIVAALLDDEATVKTFRQRDGHTWLLPQNTQYEPILGDHATIMGKVVSVLRSL
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RL6_XYLFT
Sequence: MSRVAKKPISIPKGVEVSVQSDMLTVKGVKGVLTFPKSDNVNVVMDGDILTLSANDHSHVSLAGTVRAILSNMIKGVSIGFERKLELVGVGYRASMQGKDLNLSLGFSHPLLFVPPEGINLLTPSQTEVVVQGIDKQRVGEVAAKIRNFRPPEPYKGKGLKYATEAIMRKEAKKA
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: VAP_CAMVD
Sequence: MANLNQIQKEVSEILSDQKSMKADIKAILELLGSQNPIKESLETVAAKIVNDLTKLINDCPCNKEILEALGNQPKEQLIGQPKEKGKGLNLGKYSYPNYGVGNEELGSSGNPKALTWPFKAPAGWPNQY
What is the function of this protein?
Plays a role in virus cell-to-cell and plant-to-plant transmission.  Interacts with virion icosahedral capsid and movement protein, thereby facilitating virion cell-to-cell transmission through plasmodesmata opened by viral movement protein.  Also interacts with aphid transmission factor, attaching the virion to aphid stylet when the animal feeds on an virus infected plant.  Aphid saliva may later detach the virion, inducing release of infectious particles when the animal feeds on a new plant (By similarity).
What are the official names of this protein?
Virion-associated protein, Vap, Protein 3, P3.
What is the protein family that this protein belongs to?
Belongs to the caulimovirus ORF III family.
What are the subcellular locations of this protein?
Virion. Host cell junction, host plasmodesma.
Protein: HEMH_BURL3
Sequence: MRFDLEPPSSTAAAHRIGVLLINLGTPDAPTPRAVRRYLAEFLSDPRVVEIPQAVWQVLLRTLILPLRGRASAKKYAAVWMPEGSPLRVYTERQTDSVRHLLTSNGYHVMVDYAMRYGSPNISHALAQFKRAGVERVLLMPMYPQYSASTTATAFDAAFDALARMRNQPEVRTVRHYADHPAYIHALAEQVRQYWAQHGRPDFAAGDKLVLSFHGVPKRTLDLGDPYHDQCQQTGALLTAALGLSTTECRVTFQSRFGKAEWLQPYTAPTLREFGEAGVRRADVFCPGFTADCLETIEEIGMEVRDEFLAGGGKAFHRIPCLNGAPAWIGALGEIVAENLQGWPVRAAQPETVS
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBBA_STAAN
Sequence: MQFDNIDSALMALKNGETIIVVDDENRENEGDLVAVTEWMNDNTINFMAKEARGLICAPVSKDIAQRLDLVQMVDDNSDIFGTQFTVSIDHVDTTTGISAYERTLTAKKLIDPSSEAKDFNRPGHLFPLVAQDKGVLARNGHTEAAVDLAKLTGAKPAGVICEIMNDDGTMAKGQDLQNFKEKHQLKMITIDDLIEYRKKLEPEIEFKAKVKMPTDFGTFDMYGFKATYTDEEIVVLTKGAIRQHENVRLHSACLTGDIFHSQRCDCGAQLESSMKYINEHGGMIIYLPQEGRGIGLLNKLRAYELIEQGYDTVTANLALGFDEDLRDYHIAAQILKYFNIEHINLLSNNPSKFEGLKQYGIDIAERIEVIVPETVHNHDYMVTKKIKMGHLI
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.