PharMolix/UniProtQA huggingface dataset:
Protein: ACPS_NITSB
Sequence: MIGIDIVQIERIEQLIEKYGQKGLERFLLPQEMEVAKKPQTVAGFWAAKEAVAKALKTGIGKELGFHDIFIYKTEKGAPEFKLLNGKEQMFRIQQTALSISHDAGVAVAVAVIIRC
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIHI_ECO81
Sequence: MKPSSSNSRSKGHAKARRKTREELDQEARDRKRQKKRRGHAPGSRAAGGNTTSGSKGQNAPKDPRIGSKTPIPLGVAEKVTKQHKPKSEKPMLSPQAELELLETDERLDALLERLEAGETLSAEEQSWVDVKLDRIDELMQKLGLSYDDDEEEEEDEKQEDMMRLLRGN
What is the function of this protein?
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function.  May play a role in ribosome biogenesis.
What are the official names of this protein?
Der GTPase-activating protein YihI.
What is the protein family that this protein belongs to?
Belongs to the YihI family.
Protein: ISCA_ENT38
Sequence: MSITLSDSAAARVSSFLENRGKGYGLRLGVRTSGCSGMAYVLEFVDEPATDDTVFEDKGVKVVIDGKSLQFLDGTQLDFVKEGLNEGFKFTNPNVKDECGCGESFHV
What is the function of this protein?
Is able to transfer iron-sulfur clusters to apo-ferredoxin.  Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically.  Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.
What are the official names of this protein?
Iron-binding protein IscA, Iron-sulfur cluster assembly protein.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: CLPP3_PROMM
Sequence: MIPIVIEESGRGERAFDIYSRLLRERIIFLGEPVTSDSANRIVAQMLFLEAEDPEKDIYLYINSPGGSVYDGLGIFDTMQHVKPDVQTVCVGLAASMGAFLLCAGAMGKRSSLQHSRIMIHQPLGGARGQASDIRIQADEILFLKDRLNRVLADRTGQPLERIQEDTDRDFFMSPAEAVGYGLVDSVIDKRPVHSVN
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 3, Endopeptidase Clp 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_SHEPW
Sequence: MHANELEILELTQQLNLHNYHYYVDDNPTIPDVEYDRLLKRLIELETQSPEFAKADSPTQRVGGEALAKFEQITHLKPMLSLDNVFDETEFNGFHSRITDKVGTALSYCCEPKLDGLAVSIVYRDGVFERAATRGDGQTGENITENVRTIKSIPLKLRGDNFPPLVEVRGEVIMPHKAFNALNERARAKGEKLFVNPRNAAAGSLRQLDSKITASRALGFYAYALGVVEPESWELADSHYGQLEQLRSWGVPVSQEVKVCDSVTEVMDYYNDIQQRRSSLDFEIDGVVLKVNQIAHQLSLGFVAKAPRWATAFKFPAQEEMTLLEGVDFQVGRTGAVTPVARLKPVFVGGVTVSNATLHNADEIARLGVKVGDTIIIRRAGDVIPQIVAIVADKRPDDAQDIVFPERCPVCDSEVERIEGEAVARCSGGLFCEAQRKEAIKHFASRKALDIDGMGDKVVEQLIDKELVESPADLFKLTASAMTMLERMGMKSATKLVAAIEVAKETTFARFLYALGIREVGEATAANLAAYFKTLDALKGASAEEFIKVDDVGAIVAAHLAHFLAQPHNLEVIDKLIAVGVSWPAIEEVAEEDLSLKGQTWVLTGTLTQLNRNDAKAQLQALGAKVAGSVSKNTDCLVAGAAAGSKLTKAQELGVKVIDEEALIAILS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: KDSB_LEPIC
Sequence: MMKKILGVIPARYASSRFPGKPLAKIGDKTMIEWTYRNASRSSVLSELVVATDDVRIHEVVQKFGGRSVMTSSDHPSGTDRIIEVANQFSEYSIIVNIQGDEPGIEPELIDGVASLKASHPEWAMSTAAVPLLDFSHAIDFNRVKVIIDRNGKAIYFSRSLIPSQFKTTVPLYRHLGIYGYDRDFLLQYNSLPKSNLEESESLEQLRAIEAGYGIGIYLSKEAGLSVDTPADLEIVIEDFKKRKWISE
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AB31G_ARATH
Sequence: MAAASNGSEYFEFDVETGRESFARPSNAETVEQDEEDLRWAAIGRLPSQRQGTHNAILRRSQTQTQTSGYADGNVVQTIDVKKLDRADREMLVRQALATSDQDNFKLLSAIKERLDRVGMEVPKIEVRFENLNIEADVQAGTRALPTLVNVSRDFFERCLSSLRIIKPRKHKLNILKDISGIIKPGRMTLLLGPPGSGKSTLLLALAGKLDKSLKKTGNITYNGENLNKFHVKRTSAYISQTDNHIAELTVRETLDFAARCQGASEGFAGYMKDLTRLEKERGIRPSSEIDAFMKAASVKGEKHSVSTDYVLKVLGLDVCSDTMVGNDMMRGVSGGQRKRVTTGEMTVGPRKTLFMDEISTGLDSSTTFQIVKCIRNFVHLMDATVLMALLQPAPETFDLFDDLILLSEGYMVYQGPREDVIAFFESLGFRLPPRKGVADFLQEVTSKKDQAQYWADPSKPYQFIPVSDIAAAFRNSKYGHAADSKLAAPFDKKSADPSALCRTKFAISGWENLKVCFVRELLLIKRHKFLYTFRTCQVGFVGLVTATVFLKTRLHPTSEQFGNEYLSCLFFGLVHMMFNGFSELPLMISRLPVFYKQRDNSFHPAWSWSIASWLLRVPYSVLEAVVWSGVVYFTVGLAPSAGRFFRYMLLLFSVHQMALGLFRMMASLARDMVIANTFGSAAILIVFLLGGFVIPKADIKPWWVWGFWVSPLSYGQRAIAVNEFTATRWMTPSAISDTTIGLNLLKLRSFPTNDYWYWIGIAVLIGYAILFNNVVTLALAYLNPLRKARAVVLDDPNEETALVADANQVISEKKGMILPFKPLTMTFHNVNYYVDMPKEMRSQGVPETRLQLLSNVSGVFSPGVLTALVGSSGAGKTTLMDVLAGRKTGGYTEGDIRISGHPKEQQTFARISGYVEQNDIHSPQVTVEESLWFSASLRLPKEITKEQKKEFVEQVMRLVELDTLRYALVGLPGTTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSIDIFEAFDELLLMKRGGQVIYGGKLGTHSQVLVDYFQGINGVPPISSGYNPATWMLEVTTPALEEKYNMEFADLYKKSDQFREVEANIKQLSVPPEGSEPISFTSRYSQNQLSQFLLCLWKQNLVYWRSPEYNLVRLVFTTIAAFILGTVFWDIGSKRTSSQDLITVMGALYSACLFLGVSNASSVQPIVSIERTVFYREKAAGMYAPIPYAAAQGLVEIPYILTQTILYGVITYFTIGFERTFSKFVLYLVFMFLTFTYFTFYGMMAVGLTPNQHLAAVISSAFYSLWNLLSGFLVQKPLIPVWWIWFYYICPVAWTLQGVILSQLGDVESMINEPLFHGTVKEFIEYYFGYKPNMIGVSAAVLVGFCALFFSAFALSVKYLNFQRR
What is the function of this protein?
Together with ABCG25, export abscisic acid (ABA) from the endosperm to deliver it to the embryo via ABCG30 and ABCG40-mediated import to suppress radicle extension and subsequent embryonic growth (PubMed:26334616).  Together with ABCG9, involved in pollen coat deposition of steryl glycosides required for pollen fitness (PubMed:24474628).  May be a general defense protein (By similarity).
What are the official names of this protein?
ABC transporter G family member 31, ABC transporter ABCG.31, AtABCG31, Pleiotropic drug resistance protein 3, AtPDR3.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROA_IDILO
Sequence: MVNSIHLEPRQHCRGTVTLPGSKSIANRALLMAALCQTPVILHNLLVSDDTSRMREALNALGVSFEDDKLITRVNGLGGGWNKPASELYLGNAGTAMRPLIAVLAATLKNEHQAVVLKGDARMHERPVKHLIDAIQPRGAGVNYLGETGFPPLEMTSGLKPGDFEIDGSVSSQFISALLMALPLLPGDSTLTLKGNVVSRPYIELTLQMLSDFGISIKEDSPQCYAIPGGQCYQSPGEYWVEGDASAASYWMAAALLGKGPVEIIGVGKNSIQGDKRFAEVIEAMGASVSYRKNSMTVSGTGSVQGIDQDFNDIPDAAMTVAPLALFANKPTTIRNVANWRVKETDRLHAMATELRKLGATVDEGEDFLRIEPLKHWRHIAIDTYDDHRMAMCFSLVAFSSAGVTINDPGCCAKTYPDYFSEFSRLCHS
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_CERS5
Sequence: MSDLVAKTAIDRRLADIVTPVIEGMGFELVRLRLMSGKTRTLQIMADRPDGGIVVDECADISTAVSAVLDVEDPIEDNYTLEVSSPGIDRPLTRLKDFDAWAGYEARIETAELIDGRRRFKGELAGTEGDEVLITIEDGKEGFVTIGLKFDWLSDAKLILTDELIAEMLRQKKASGNFDESQFDEIQETEGEEADEAETPITRH
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y760_RICPR
Sequence: MHNADCNWKNIMQSFTESPNDFSILHQECSSGLNIPINNIFTDTENNTHLLLDQTVTHNQNGTANILGKIYKVTNGYMFSQGDITSTNGANFLGLNQCTEEAAISVLQNYHSYKETLIPRASFINTLAETLNHLGLYLDNISPMEIGKYILDQFGKTYDEPTTEKSNNDTNCHEYSNSYYYVVALGTLALGSILGYTAKYVWDNYNGKNIKNENIELVRENKQLKFSTLLYENFKNNAFILDEIIKINNLNDIIKLAKSMQEFKSSISSLTNLNNEIIKLNSPSAIALNLASVSKILHEICDNLKGNDSFTTINNFAKLITMIRTENPDSEEYKASIKEILEIFSSHYEEIEELNYATPLLAIEAYSPLEIIE
What are the official names of this protein?
Uncharacterized protein RP760.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GSHB_XANAC
Sequence: MSLDVVVVMDPIASIKIAKDTTFAMLLEAQRRGHRLHYVRPGGLSLREGRAVAQVAPLSVREDKTSWFTLGEFAELAFGPGQVVLMRKDPPVDAEFVYDTQVLSVAQRAGAQIVNDPQGLRDYNEKLAALLFPQCCPPTLVSRDAAALKAFVLEHGQAVLKPLDGMGGRSIFRSGSGDPNLNVILETLTDGNRKLTLAQRFIPDITAGDKRILLVDGLPVDYCLARIPQGDEFRGNLAAGGRGEGRPLSERDRWIAAQVGPEMRRRGMRFVGLDVIGDYLTEVNVTSPTCVRELDAQFGLNIAGLLFDAIEAGAAQ
What are the official names of this protein?
Glutathione synthetase, GSH synthetase, GSH-S, GSHase, Glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic GSH synthase family.
Protein: EI2BE_RAT
Sequence: MAATAAVPSAVGGRANKRGGGSGGGGTQGAEEEPPPPLQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLQKSKWCHPTSLNVVRIITSDLYRSLGDVLRDVDAKALVRSDFLLIYGDVVSNINISKALEEHRLRRKLEKNVSVMTMVFKESSPSHPTRCHEDNVVLAVDSTTNRILHFQKTQGLRHFSFPLGLFQGSLDGVEIRYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVNEEILGNQIHLHVTSREYGARVSNLHMYSAVCADVIRRWVYPLTPEVNFTDSSTQSYTHSRHNIYRGPEVSLGHGSVLEENVLLGAGTVVGSNCSITNSVIGPNCHIGDNVVLDQAYLWQGVRVAAGAQIHQSLLCDRAEVKERVILKPHCVLTSQVVVGPDIILPEGSVISLHPPDAEEDEDDGQFSDDSGADQEKEKVKLKGYNPAEVGPEGQGYLWKAEDVDEKEDEELRQSLWGLMINMEEESETESERSVDPEELDSRAGSPQLDDIRVFQNEVLGTLQRGREENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQQVDGVLDPNRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHETLVPSLAKVLMAFYQLEILAEETILSWFSQRDITDKGQQLRKNQQLQRFIQWLREAEEESSDDD
What is the function of this protein?
Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
What are the official names of this protein?
Translation initiation factor eIF-2B subunit epsilon, eIF-2B GDP-GTP exchange factor subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B gamma/epsilon subunits family.
Protein: YQEC_BACSU
Sequence: MKIGLIGLGKMGINIGKQFIDRNHQVVGYDVNQAAVDELKAYGAEGTTNLKEFISLLHPPRILWVMVPHGIVDAVLRDVSPLLSKGDMIIEAGNSHYKESIRRYNQMKEAGIHYLDAGTSGGMEGARHGACFMVGGDHEAWEIVEPLFRDTAVENGYLYAGEAGSGHFLKMIHNGIEYGMMAAIGEGFEVLENSQFDFDYEKVARVWNHGSVIRSWLMGLTERAFAKDAKLDQIKGIMHSSGEGKWTVETALDLQTATPVIAMSLMMRYRSLTDDTFTGKVVAALRNEFGGHATEKK
What is the function of this protein?
May act as NAD-dependent 6-P-gluconate dehydrogenase.
What are the official names of this protein?
Putative 6-phosphogluconate dehydrogenase YqeC.
What is the protein family that this protein belongs to?
Belongs to the 6-phosphogluconate dehydrogenase family.
Protein: H2AXA_ARATH
Sequence: MSTGAGSGTTKGGRGKPKATKSVSRSSKAGLQFPVGRIARFLKSGKYAERVGAGAPVYLSAVLEYLAAEVLELAGNAARDNKKTRIVPRHIQLAVRNDEELSKLLGSVTIANGGVLPNIHQTLLPSKVGKNKGDIGSASQEF
What is the function of this protein?
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.  Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation (By similarity).
What are the official names of this protein?
Probable histone H2AXa, HTA5.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: YQGF_ACAM1
Sequence: MQRISALGLDLGHRRIGVAGCDGTGLIATGLTTIRRTSFTKDMEILRQIVVDRQVKTLVVGLPYTMKGEVGTQAQKTQKLAKRIAKALDLPLDFIDERLTSHEAESMMREQRINPAEQKGMIDRKAAALILQRWLDQKPWLSST
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_SALA4
Sequence: MDKKSARIRRATRARRKLKELGATRLVVHRTPRHIYAQVIAPNGSEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGRVQALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: MURB_STRU0
Sequence: MIEELAGIDIRINEPLKKYTYTKVGGPADYLVFPRNRLELTRVVKYANNHSIPWIVLGNASNLIVRDGGIRGFVIMFNKLNTVTVDGYTIEAEAGANLIETTKVAKFHSLTGFEFACGIPGSVGGAIFMNAGAYGGEIANIFLSAKVLTPEGDIKTMTAREMAFGYRHSAIQKSGDIVISAKFALKPGDFEQISQEMNRLNYLRQLKQPLEYPSCGSVFKRPEGHFAGQLIMEAKLKGYRIGGVEVSEKHAGFMINVDHGTAKDYEHLIAHVIETVEHNSGIRLEREVRIIGEQESLNQKEKS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDPX_SYNY3
Sequence: MSFDTPLKPYLAIPIQDCGEPLAPINLEGVKSLKPHPYAQVGADYQGRSPYVLRTGVLKRLDQARLTLADIEPSWEILVFDAYRPIAVQQFMVDHTFAEIVARDGLQGQVLTPEQKENIYHQVYQIWAVPNNNPLTPPPHSTGAALDITLLDDLGQPVDMGGEIDELSARSLPNYYQTVEPNSDRQRKEFEQYQRRRELLNTIMESAGFLRHPGEWWHFSQGDQLWAWQYNQRHPDHQKIAYYGRVE
What is the function of this protein?
Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.  May have a role in cell-wall turnover.
What are the official names of this protein?
D-alanyl-D-alanine dipeptidase, D-Ala-D-Ala dipeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M15D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACUK_PARBD
Sequence: MTSSARNGSPSPSPALPSTTTPAEQESRNTMTTANNPGDWDSSESRPQPLSNGKGVGNGMVANGHQRPSTSSTAASANNASAKDPLRPRRKKAKRACFACQRAHLTCGDERPCQRCIKRGLQDTCHDGVRKKAKYLHDAPNEALIPGIRGNLYSQAQAARNKINTNSQQRNGTNSNSDNNSTNTNSNNKPSHQDVSTNFFSTPSTNNYNTVYTQAKSRQSQHMPSRVMQDATMNPSAFQAQPPASPTFDLSSNPQNHTLSPSMAQNSGTTPSSSASQNPDPYGPTFFDPSHPALFNFDIASMNFGNRYGALEFGMLGHLATGAGDTPPSDSATRRGSIGRSSGTFTVQNFGEGSSNQSPFLFGGDPVLNDWNPAGQGQTNSRNIYNQNSVSGQMADHPHAFAIESAPMNFASPSSTESPQMTTVTQFDDPSVNFSSRTTLMPPTNTQHQQQPQPPRISTPSLKNMQVGVKRRYRSPSSIYESVKEPYSYTSGFHSLTAFIQRRFSPQKTLQIAKALASIRPSFIATTKTLNQDDLIFMEKCFQRTLWEYEDFIDACGTPTIVCRRTGEIAAVGKEFSILTGWKKEVLLGKEPNLNVNTGGSSSSGVSSRGSSTYNSRNSATMTVMDNQSLPTGRTQPVFLAELLDDDSVIEFYEDFAKLAFGDSRGSVMTTCKLLKYKTKEDGVGLFRNSNGEVSAAGGGGTAADDTDANDGAGAGAGDGTTSAVNGVSNGSGNNATNVNANGNVNVIPNDLSGASSMKLSPKQAWGKSRIAGEAGMNQLGFRDGKVECSYCWTVKRDVFDIPMLIVMNFLPCI
What is the function of this protein?
Transcription factor which regulates nonfermentable carbon utilization.  Activator of gluconeogenetic genes (By similarity).
What are the official names of this protein?
Transcription activator of gluconeogenesis PADG_03802.
What is the protein family that this protein belongs to?
Belongs to the ERT1/acuK family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROK_DECAR
Sequence: MSTQDSAKITTVEHRRNIYLVGLMGAGKTTVGRQLARRLSRPFFDTDHEIVERTGVPIPTIFEIEGEEGFRRREAQTIYDLTAENNIVLATGGGVVINPENRRRLHDTGWVVYLNVSPVLLYERTRHDRNRPLLRVEDPLAKLEELHSIRDPLYREVAHIVVDGSHLVASGIVQYLLREFNRL
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRM7_RAT
Sequence: MVQLGKLLRVLTLMKFPCCVLEVLLCVLAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAKGPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSLTFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLCIAQSVRIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAKRADQVGHFLWVGSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRRNVWFAEYWEENFNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAHALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRHVNFNGSAGTPVMFNKNGDAPGRYDIFQYQTTNTTNPGYRLIGQWTDELQLNIEDMQWGKGVREIPSSVCTLPCKPGQRKKTQKGTPCCWTCEPCDGYQYQFDEMTCQHCPYDQRPNENRTGCQNIPIIKLEWHSPWAVIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIWFGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSSRLSHKPSDRPNGEAKTELCENVDPNSPAAKKKYVSYNNLVI
What is the function of this protein?
G-protein coupled receptor activated by glutamate that regulates axon outgrowth through the MAPK-cAMP-PKA signaling pathway during neuronal development (By similarity).  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase that it inhibits.
What are the official names of this protein?
Metabotropic glutamate receptor 7, mGluR7.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FAD2_SIGCA
Sequence: MGGGGQLGESGENGCKSAAGVYTWEEVQHHSNRNDQWLVIDRKVYNVTQWAKRHPGGFRVLNHYAGEDATEAFTAFHPDIKFVQKYMKPLLVGELAATEPSQDQDKNAALIQDFHTLRQQAESEGLFQARPLFFLLHLGHILLLEALALLMVWHWGTGWLQTLLCAVMLATAQSQAGWLQHDFGHLSVFKKSRWNHLVHKFVIGHLKGASANWWNHRHFQHHAKPNIFKKDPDINMVDLFVLGETQPVEYGIKKIKNMPYNHQHKYFFLVAPPLLIPVFYNYNIMMTMITRRDYVDLSWAMTFYIRYMLCYVPVYGLFGSLALMMFARFLESHWFVWVTQMSHLPMDIDNDKRRDWLSMQLQATCNIEKSFFNDWFSGHLNFQIEHHLFPRMPRHNYHLVAPQVQTLCEKHGIPYEVKTLWKGMVDVVRALKKSGDLWLDAYLHK
What is the function of this protein?
Fatty acid desaturase with bifunctional delta-4 and delta-5 activities.  Component of a lipid metabolic pathway that catalyzes the biosynthesis of polyunsaturated fatty acids (PUFA) with preference toward n-3 substrates and Delta(4)function.
What are the official names of this protein?
Acyl-CoA Delta-4 desaturase, Delta(4)/Delta(5) fatty acid desaturase, D4D/D5D fatty acid desaturase, Delta-4/Delta-5 fatty acid desaturase, FAD2, Delta-4 desaturase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RT106_PICGU
Sequence: MQWLHTLPPPLQDEVAALISAVPQAAPTLDKLFEYASNSPQKQKIPDPPRKKRQQTSAPPQLPPPLTQADIIFHLSNISCQSPFRKRLGFAFHLALGPQGPVPALSLVNNQLQPEFSLMNLGQDIVFCSLLPILGNSTVSSKKDTVLLLVWLAHGDPIVCQLNFDAVKKQLVAEGKVPASAESELDSESEEDDAEGIRPINEALVDFLVRQFQLCGIRLLNYLPFSTGSKNKLTLNKDTALALSTNGTSVNDVVIVQAYRGSKDGALVLLGGTQDQPGTIIFGFRKPILLFRANSVKRISYSNITRLTFNVSVTVHNDTRPDGEETIEFSMLDQAYFQILDDFVKRQGINDDSFNEALREKQKADPNVKAETDAEDAEAPDSDDEEEDGTYQAGVESDSDNEKKEEDGEENSEDEDSEDGEESEDSEDGELSEDGESDDLSLS
What is the function of this protein?
Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing.  Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA.  Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter (By similarity).
What are the official names of this protein?
Histone chaperone RTT106.
What is the protein family that this protein belongs to?
Belongs to the RTT106 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ILVC_CHLTE
Sequence: MNIYYEQDADLAVLQNKNIAILGYGSQGHAHALNLKDSGMNVCVGLKTDSASCAKAREAGLKVDTVAEAVKWADIVMILLPDQTQKSVYDNEIAPNLKSGATLAFGHGFNIHYKQIVPPADVNVIMIAPKSPGHLVRRTYTEGNGVPCLIAVHQDATGDAKAIALAWAKGIGGTKAGVIETSFKDETETDLFGEQAVLCGGSAELIKAGFETLTEAGYPAELAYFECMHELKLIVDLYYEGGLSRMNYSVSDTAEYGGMTRGPRVVTSAAKAEMKKILEEIQDGRFAKEFIDECNSGYKKMNELRESNRNHPIEVVGAKLRGMMSWLKKK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: RR2_POPTR
Sequence: MIRRYWNINLKEMLETGVHFGHATRKWNPKMAPYISAKRKGIHITNLTRTARFLSEACDLVFDAASRRKQFLIVGTKNKAADPVARAAIRARCHYVNKKWLGGLLTNWSTTEMRLQKFRDLRMEQKTGGIHRLPKGDAARLKRQLFHLQTYLGGIKYMTGLPDIVIIVDQQEEYMALQECITLGIPTICLIDTNCDPDLTDISIPANDDAIASIRLILNKLVFAICEGRSSYIRNP
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NPY2R_CAVPO
Sequence: MGPIGTEADENQTVEEIKVEPYGPGHTTPRGELAPDPEPELIDSTKLTEVRVVLILAYCSIILLGVVGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTVTLTVIALDRHRCIVYHLDSKISKQNSFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISVSYVRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVFVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCQQRLDAIQSEVCVTGKAKTNVEVEKNHGAADSAEATNV
What is the function of this protein?
Receptor for neuropeptide Y and peptide YY.
What are the official names of this protein?
Neuropeptide Y receptor type 2, NPY2-R, NPY-Y2 receptor, Y2 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HSLO_STAA1
Sequence: MTHDYIVKALAFDGEIRAYAALTTETVQEAQTRHYTWPTASAAMGRTMTATAMMGAMLKGDQKLTVTVDGQGPIGRIIADANAKGEVRAYVDHPQTHFPLNEQGKLDVRRAVGTNGSIIVVKDVGMKDYFSGASPIVSGELGEDFTYYYATSEQTPSSVGLGVLVNPDNTIKAAGGFIIQVMPGAKDETISKLEKAISEMTPVSKLIEQGLTPEGLLNEILGEDHVQILEKMPVQFECNCSHEKFLNAIKGLGEAEIQNMIKEDHGAEAVCHFCGNKYKYTEEELNVLLESLA
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.