PharMolix/UniProtQA huggingface dataset:
Protein: PIMA_MYCTU
Sequence: MRIGMICPYSFDVPGGVQSHVLQLAEVMRTRGHLVSVLAPASPHAALPDYFVSGGRAVPIPYNGSVARLRFGPATHRKVKKWLAHGDFDVLHLHEPNAPSLSMLALNIAEGPIVATFHTSTTKSLTLTVFQGILRPMHEKIVGRIAVSDLARRWQMEALGSDAVEIPNGVDVDSFASAARLDGYPRQGKTVLFLGRYDEPRKGMAVLLDALPKVVQRFPDVQLLIVGHGDADQLRGQAGRLAAHLRFLGQVDDAGKASAMRSADVYCAPNTGGESFGIVLVEAMAAGTAVVASDLDAFRRVLRDGEVGHLVPVDPPDLQAAALADGLIAVLENDVLRERYVAAGNAAVRRYDWSVVASQIMRVYETVAGSGAKVQVAS
What is the function of this protein?
Involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM).  Catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1) (PubMed:15939292).  PimA plays an essential role for growth in macrophages and during both the acute and chronic phases of infection (PubMed:25049093).
What are the official names of this protein?
Phosphatidyl-myo-inositol mannosyltransferase, Alpha-mannosyltransferase, GDP-mannose-dependent alpha-(1-2)-phosphatidylinositol mannosyltransferase, Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase, Phosphatidylinositol alpha-mannosyltransferase, PI alpha-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS18_CLOBM
Sequence: MAGREGGRRQRRTKRKVCTFCAEKSEAIDYKDINKLRKFVTERGKILPRRISGNCAKHQRELTRAIKRARNIALLPFTTE
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RL3_AZOSB
Sequence: MSLGLVGRKVGMTRIFADDGRSIPVTVLDVSDNKVTQIKTPEADGYSAVQVAFGKRRASRVVKPIAGHLAKAGVEPSRVLKEFRVEPEGLASLKAGDQVSVEIFSVGQKVDVTGVSIGKGFSGPIKRHNFSSNRASHGNSVSHNSPGSIGMAQDPGRVFPGKRMAGQYGAVQRTTLGLEVVRVDAERQLLLVKGAVPGAKGGDVVVRPAIKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RIMP_AZOSB
Sequence: MQAGVENLVEQVVSGLGYELVDFELSPKGRLLRVFIDIERGVTVDDCATVSNQLTRVFEVENVDYDRLEVSSPGLDRPLKKLADFERFAGQEIQLRLSLPIGNQRNFVGVLQGVRESSVVLLTEKGELLAPFEEIEKARLVPKF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CID2B_BRAFL
Sequence: MEFLSKIVRVHIPDYLNSVPVPDSFGGFLDLTAGQWLHLFAFSGTVAAAVYVSVKPYLDKKDQKDQLVNLRIQKESSKVVNMVDIEDLGNKVCYCRCWRSKKFPLCDGSHAKHNEDTGDNVGPLVLKRKDV
What are the official names of this protein?
CDGSH iron-sulfur domain-containing protein 2 homolog B.
What is the protein family that this protein belongs to?
Belongs to the CISD protein family. CISD2 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: SHC1_SCHJY
Sequence: MKTDGNTTLDTTISMEELERTVKSAYEALAKDQQDDGHWIYELEADVTIPAQFILLEHTLDKIDEELEQKIANYLRRCQSREHWGWPVYYGGEFNISASVQAYFALKMTGEDINAPHMVRAREAILAHGGPEYANVFTRIQLSLFGEASWLATPFMPVEIMLLPRWMYFSIWNMSYWSRTTVAPLLIVADLKPKAINPRNVHIPELFPTPPDKVKTWIHGPFRSKWGHVFKFIDTAIRPFTRFVPSFLHKKAYKAALDFIEPRLNGVDGLGAIYPPMSYSAVMYRALGIPDDDPRAATNWEALKGLLVIKEREAYCQACVSPVWDTALSGHALMEASFGPDGINADRTEKLIDRAAHWLRAHQVLNVVGDWAINNPNLQPGGWAFQYGNDYYPDVDDTAVAAMLLHRQNLPENEEALDRARKWIIGMQSSNGGWGAFDIDNDKQILNDIPFADHGALLDPPTADVSARCISLLAELGHPEDRPVIERGIKYLRKEQEEDGSWFGRWGTNYIYGAWSVLCAFNASGVPHDDPSVLKCVNFLKSVQREDGGWGESCETYEGSAHGVYTESLPSQTAWAVLGLMASGRRTDPAVKRGIVWLIQHQQDNGEWAEEPFNAVGFPRMFYLHYLGYKQFFPLLALARYRHMEKSGTNNVSFAF
What is the function of this protein?
Squalene cyclase that catalyzes the oxygen-independent cyclization of squalene into hopanoids, a class of cyclic triterpenoids including hop-22(29)-ene, hop-17(21)-ene, hop-21(22)-ene, and hopan-22-ol.
What are the official names of this protein?
Squalene-hopene cyclase, SHC.
What is the protein family that this protein belongs to?
Belongs to the terpene cyclase/mutase family.
Protein: PXPA_STAAM
Sequence: MRVDLNCDLGEAFGNYSFGGDHQIIPLITSANVACGFHAGDENVMNETVKLAKAHNVAVGAHPGLPDLKGFGRRNIDISNDEIYNLMIYQLGALQGFCRIHQLKINHVKPHGALYQMGAKDREIANVIAQAVYDFDPSLVLVGLANSYLISEAKNVGLITASEVFADRRYEDDGQLVSRKESDAVITDTDEALKQVLKMVKENKVISKNNKEVTLQADTICVHGDGEHALLFVSKIREILMKEGIDIQSL
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: HIS7_CALS4
Sequence: MRKAEVKRKTAETDIYVELNIDGKGSYDIKTGIGFFDHMLSLFAKHGLFDLKVIAKGDLEVDTHHTVEDVGIVLGTAFLKASGDKKSIKRFSTFYVPMDEALVRVSLDISGRPYLYYDLPLKAERVGNFETETVEEFFRAFAYNFGITLHVELLHGVNTHHIIEASFKALGKALDEALKLDERIDGIPSTKGIL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNE_ERWT9
Sequence: MNILLIILASLFSCAGQLCQKQATTVSGGRRPLLLWLGGSVLLLGMAMLVWLRVLQTVPVGVAYPMLSLNFIFVTLAARWLWRETLSLRHALGVILIVAGVAIMGSYT
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE, L-Ara4N-phosphoundecaprenol flippase subunit ArnE, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnE.
What is the protein family that this protein belongs to?
Belongs to the ArnE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYP_NATPD
Sequence: MTDQELGITESKEHNPGEWYAEVVQKAGLADYAPMGGFIVTRPRGYALWERLQDHLDGWFKETGVQNTYFPMFIPESYLEREKDIVDGFDPEVAWVTHGGHDELEERLAVRPTSESIITPFIAEWVRSYRDLPLRVNQWCSVVRWEATETKPFFRTKEFLWQEGHTAHATEESAWDETMTRLEQYERLYEEVMAIPGMTGRKPEHDKFPGADTTTTIEALMPDGKSVQAGTSHYLGTSFAEAFDIEYTDEDETKQTAHTTSWGLSWRALGALIMTHSDDQGLVIPPALAPTQVVVVPIWQADTEEAVKEYAADLAAELDEQFRVELDDRDERNPGFKFNEHELQGVPLRIEIGPNEVEDEAATLVHRPDGESDVAERESITDAVDEALETVYAKLYASAEATLEENIRKAHGRGEILGTLGQHGGYVKTGWCGDEACEAEIKDEIAAEIVMLPLDEDEPPVYDTCGVCGDEATETAYFAKSY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HDA_SALA4
Sequence: MSSWVEVSLNTPAQLSLPLYLPDDETFASFWPGDNASLLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVPEVLDGMEHLSLVCIDNIECVAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDHASITAQRKLTIPFVKEILKL
What is the function of this protein?
Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN).  Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity).
What are the official names of this protein?
DnaA regulatory inactivator Hda.
What is the protein family that this protein belongs to?
Belongs to the DnaA family. HdA subfamily.
Protein: SFSA_SYNS9
Sequence: MPLLEFEPLQEGVLIKRYKRFLADIELSNGEVVTAHCANTGPMTGVLIPGQRVRLRHAPSPKRKLAWTWEQAEVPGADGQPCWAGINTALPNRLIRATIEAGCLSEQLGAISNIRAEVAYGTNRRSRIDLLLTPGESNPDQRLIYLEVKNTTWTDGTTALFPDTVTERGQKHLIELMGVLPEARAVLVPCLSRPDVMDFAPGDEADPRYGSLFRDALEAGVEVLPCCFRYQSNEISWQGLRPLKKFQNL
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: FOLD_BRUME
Sequence: MAQLIDGKKLAEDVVSTVKTETEKLVAATGVVPGIAVVIVGEDPASQVYVASKSRKAKECGFHSVQHDLPETASEQELLNLIEGLNNDPAIHGILVQLPLPGHIDSGRVIQTIAPEKDVDGFHFINVGKLGTGEVETAFVPCTPAGAMIMIERVHGRDLSGLNAVVIGRSNIVGKPMFNLLLAANATVTVAHSRTKDLPAIARNADILVAAVGRPQMVKGDWVKPGATVIDVGINRIPAPERGEGKTRLVGDVDFAEAEKVAGAITPVPGGVGPMTIAMLMANTLTAACRSAGMKKPVF
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: MIAA_CHLT2
Sequence: MSSSSSSGAATGFAVCSDPQKSFSKMFKRTVILLAGPTGSGKTAVSLKLAPLVDGEIISVDSMQVYQGMDIGTAKVSLADRKEVPHHLIDVCHVQESFNAVDFYYHAVQACQDILSRNKVPILVGGTGFYFHTFLSGPPSGPSPDFVLREQLTLEAQERGISALYQELELLDPVYAATITKHDKNKIIRALEIIRKTGSKVSSYAWQSTVNESKEYHCRGWLLSPDPELLRHNILERCDQMLEEGLLDEVQALLAAGIKGNSSASRAIGYREWIEFLDLGSPPDLFEITKQKFITNTWRYTKKQRTWFKRYSLFRELRPMGMTLDDMAKKIAQDYFLCG
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: YTES_BACSU
Sequence: MTKRIRTALCVIVSVLFLASCSSRPDGMHVILFSDMQAGVQEKIKKAAEQNAGKVDIFPAFQEKLLTEITAHEGDVFIVPEDMFQAYDDPENFQPLNGLPPEKTSPYTTVNKKTGEKTIYAVQIEKGKKQLNGYSFQLNRDMAAFIPVYAEKTEEALQLISQLTEAR
What is the function of this protein?
May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls.
What are the official names of this protein?
Putative lipoprotein YteS.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: PTFAH_VIBCH
Sequence: MLELTTQDIQLQQHFANKQAAIQGLAHALTAKGLVAEGYAQGMLNREAQHSTYLGNGIAIPHGTTDTRELVKQTGVTAMHFPQGLDWGDGNLVYVAIGIAAKSDEHLGILKQLTRVLSADGVEQALQQAKTAQQIIAIIKGEAQLTADFDASLIQLQFPASDMVQMSAVAGGLLKNTGCAENEFVADLVTKAPTHLGRGLWLVASDRAVKRTGMSIVTTANHCEYEQQAVKALIAFSVCNDVHQPLLNTITQCVFEQKQDQLLQADVQQLLNLFSGNAEQTIAQRTIAVGTITEETIAAETVAEPDSARAHTATFRIKNSHGLHARPGAMLVAEAKKFESNIRVSNLDGDGQVVNAKSLMKVIALGVKHNHQLQFTAEGPDAEAALQALGVAINAGLGEG
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II FruAB PTS system is involved in fructose transport.
What are the official names of this protein?
Multiphosphoryl transfer protein, MTP.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU6C_HELAN
Sequence: MDLPGLIHDFLLVFLGLGLILGGLGVVLLANPIYSAFSLGLVFVCISLFYILSNSHFVAAAQLLIYVGAINVLIIFAVMFINGSEYSKDFHLWTVGDGVTSVVCTSLFVSLITTIPDTSWYGIIWTTKANQIIEQDLISNSQQIGIHLSTDFFIPFEFISIILLVALIGAIAVARQ
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: 3S11_HOPST
Sequence: MKTLLLTLVVVTIVCLDLGYTMTCCNQQSSQPKTTKTCAESSCYKKTWRDHRGTITERGCGCPSVKPGIQLECCKTNECNN
What is the function of this protein?
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
What are the official names of this protein?
Short neurotoxin 1, SNTX-1.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS18_HELHP
Sequence: MEKKKYSKRYCRYTEAKLEYIDYKDVEMLKHSLSERYKIMPRRLTGNTKRWQERVEVAIKRARHMALIPYIVDRKKVVENPFKI
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RL4_MYCGA
Sequence: MSKIKLFDLSGKVQEEIELNQKLLVSEVHKQAIFDAILAENLSQIQGTHSTLKKGEVSGGGKKPYQQKHTGRARQGSIRNPHYVGGGIAFGPKPNRNYKIKVNKKVSSLAFKSAITSKVNNNEFLGLVDSIKQDKPSTKAIAKLLKELKVNKKVLIVAFEKNENLEKSSANLPNVSYKLWNQVSVKDLIDANCVLAQKSAINNWVERLN
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: ATG15_PENRW
Sequence: MPRKRSRFELSIHSLLLSVAVLSGAAYASGYYPPSQQVPIIPPQVPLKGAEATPDIHEFSLRHIFHRGTYEQPDFHARLDVKPDTRLRTVSEDGHEEEYIASESSLLASSSPLTIQRLADRRLPVIQGHLAAARSSGFAAALSPQEWALDTLPGPNITDKPTVLTFAQMTANDYIEEPGTGQWHTINGKFNYSGSFGWQKDGLRGHIYSDKTNGTVVISLKGTSPALFDGAGTTTNDKVNDNLYFSCCCGQGGSYLWRQSCDCQSATFTANLTCIIESMTDEDRYYRAAIDLYSNVTEIYPDANIWMTGHSLGGAMTSLVGLTFGLPVVTFEAVPEALPAARLGLPSPPGYDPRFPQSRQYTGAYHFGHTADPVFMGTCNGINSICTWGGYAMESVCHTGQVCTYDTVADKGWRVGLGTHKIENVISDVLMTYDSVPSCVAEEECFDCELWKFFRSNGSEITTTTTTTTTTTSPTRTSTCKTPGWWGCLDESTTATTTTTTTTTSTATTTTCMTPGWFGCNDPTTTTATPAPTVTTTLPTVTSTTTSCHDPGWFGCRDETSTVATTTANPASPTSTACHSPGIFWGCWDEPTSTTAVTSLPAFTSAPISTTCHSPGIFWGCWDEPTSTTAVTSLPAITSTPISTTCHIPGIFWGCWDEPTNTPAVTSAPTPTS
What is the function of this protein?
Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies.  Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles.  The intravacuolar membrane disintegration by atg15 is critical to life span extension (By similarity).
What are the official names of this protein?
Putative lipase atg15, Autophagy-related protein 15.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Endosome, multivesicular body membrane; Single-pass type II membrane protein. Prevacuolar compartment membrane; Single-pass type II membrane protein. Note=From ER, targeted to vacuolar lumen at the MVB vesicles via the Golgi and the prevacuolar compartment (PVC).
Protein: GLMU_CAUVC
Sequence: MTESVSKPVRPRAAVILAAGQGTRMKSPTPKVLHRLAGRTLLDHAIDAAEGLGCERIIVVVGAHSPQVGESARKRLGPDATVIQDPPLGTGHAVLAAKDALADFHGDVVVTYADCPLTTAPVIAPLFDLITHVAHVAVLGFEAQNPTGYGRLILAPGHVLLRIVEEKEADLATKQVKHCNSGVLAADRAVLFDLLANVRNDNAKGEYYLTDVVGLAHERHLSTRTAFAPEASVQGVNAQAELAAAEAVWQQNRRKALMVDGVTMPAPDTVHLAWDTQIAGGAVVEQFVVFGPGVSVASGAVIKAFSHLEGAVVGEGALIGPYARLRPGAEIGPDAHIGNFVEVKKVKVGAGAKANHLSYLGDGSVGEKANIGAGTIFCNYDGFEKFETHVGKGAFIGSNSALVAPVRVGDGAMTGSGSVITKDVEDGALALSRADQTSKAGWATKFRAIKQAQKDKKKDKKA
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAC_PSEE4
Sequence: MLTHLDSQGRANMVDVTEKAVTAREAIAEARVRMLPDTLRMIVDGQHPKGDVFAVARIAGIQAAKKTSDLIPLCHPLMLTGVKVELAAEGEDVVHIVARCKLAGQTGVEMEALTAASVTALTIYDMCKAVDKGMVIEQVRLLEKTGGKSGHYKVEA
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: COAD_THISH
Sequence: MQVIAVYPGTFDPITNGHTDIVRRATRLFDRVVVAVAASPAKQPFFNLDERVGLARDALSGLGNVEVTGFSGLLAKFMREQQAQVILRGLRAVSDFEHEFQLAGMNRHLAPELETLFLTPAEEFAYVSSSLVREIAALGGDVSHFVSGPVVAALKARMG
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_RABIT
Sequence: MAYPFQLGFQDASSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAIILILIALPSLRILYMMDEINNPSLTVKTMGHQWYWSYEYTDYEDLNFDSYMIPTSDLNPGDLRLLEVDNRVVLPMELPIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATLISTRPGLFYGQCSEICGSNHSFMPIVLEMVPLKHFENWSLSMI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SDRE_STAAE
Sequence: MINRDNKKAITKKGMISNRLNKFSIRKYTVGTASILVGTTLIFGLGNQEAKAAENTSTENAKQDDATTSDNKEVVSETENNSTTENNSTNPIKKETNTDSQPEAKKESTSSSTQKQQNNVTATTETKPQNIEKENVKPSTDKTATEDTSVILEEKKAPNNTNNDVTTKPSTSEPSTSEIQTKPTTPQESTNIENSQPQPTPSKVDNQVTDATNPKEPVNVSKEELKNNPEKLKELVRNDSNTDHSTKPVATAPTSVAPKRVNAKMRFAVAQPAAVASNNVNDLIKVTKQTIKVGDGKDNVAAAHDGKDIEYDTEFTIDNKVKKGDTMTINYDKNVIPSDLTDKNDPIDITDPSGEVIAKGTFDKATKQITYTFTDYVDKYEDIKSRLTLYSYIDKKTVPNETSLNLTFATAGKETSQNVTVDYQDPMVHGDSNIQSIFTKLDEDKQTIEQQIYVNPLKKSATNTKVDIAGSQVDDYGNIKLGNGSTIIDQNTEIKVYKVNSDQQLPQSNRIYDFSQYEDVTSQFDNKKSFSNNVATLDFGDINSAYIIKVVSKYTPTSDGELDIAQGTSMRTTDKYGYYNYAGYSNFIVTSNDTGGGDGTVKPEEKLYKIGDYVWEDVDKDGVQGTDSKEKPMANVLVTLTYPDGTTKSVRTDANGHYEFGGLKDGETYTVKFETPTGYLPTKVNGTTDGEKDSNGSSVTVKINGKDDMSLDTGFYKEPKYNLGDYVWEDTNKDGIQDANEPGIKDVKVTLKDSTGKVIGTTTTDASGKYKFTDLDNGNYTVEFETPAGYTPTVKNTTADDKDSNGLTTTGVIKDADNMTLDRGFYKTPKYSLGDYVWYDSNKDGKQDSTEKGIKDVTVTLQNEKGEVIGTTKTDENGKYRFDNLDSGKYKVIFEKPAGLTQTVTNTTEDDKDADGGEVDVTITDHDDFTLDNGYFEEDTSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDAGKHTPVKPMSTTKDHHNKAKALPETGSENNGSNNATLFGGLFAALGSLLLFGRRKKQNK
What is the function of this protein?
Cell surface-associated calcium-binding protein which plays an important role in adhesion and pathogenesis.  Contributes to the resistance to killing by innate immune components in blood and thus attenuates bacterial clearance by interacting with host complement factor H/CFAH and modulating its activity (PubMed:22675461).  Inhibits also bacterial opsonization and killing by interacting with host complement regulator C4BPA and thus inhibiting classical complement pathway activation (PubMed:24600566).
What are the official names of this protein?
Serine-aspartate repeat-containing protein E.
What is the protein family that this protein belongs to?
Belongs to the serine-aspartate repeat-containing protein (SDr) family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Anchored to the cell wall by sortase A.
Protein: MTNA_LACBS
Sequence: MALISIRTSDDKIEIINQLLLPHVTEFVQIDTIEQAHDAIKTMKIRGAPAIASLAALSFSQYLSRALQASPLPEYFASPEALKNNLEPVLAYLFTARPTAVNLGAATRRLTTTLNQSIAQGKTTRSIAQDLIDEGKAIADEDVGRNKAMSKWGGDWLFDRVKAGGGSAEKGLNVLTVCNTGSLATSGYGTALGLITYLHETGKLEKAYYTQTAPYHQGSRLTALELKTLNIPSVMICDTMVGSLFQHFNIHAVVVGADRIAKNGDTANKIGTYNAAVIAARHNIPFIVVAPISTVDLAVESGLDIPIEQRPPIEACLVRGILYPNDGNSKQAQVMITPSGLDGIYNPSFDVTPAGLITAIVTEKGVAVKGEGENIFDLTPVV
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: BLUR_ECOLI
Sequence: MAYYSIGDVAERCGINPVTLRAWQRRYGLLKPQRSEGGHRLFDEEDIQRIEEIKRWISNGVPVGKVKALLETTSQDTEDDWSRLQEEMMSILRMANPAKLRARIISLGREYPVDQLINHVYLPVRQRLVLDHNTSRIMSSMFDGALIEYAATSLFEMRRKPGKEAILMAWNVEERARLWLEAWRLSLSGWHISVLADPIESPRPELFPTQTLIVWTGMAPTRRQNELLQHWGEQGYKVIFHAP
What is the function of this protein?
Controls the expression of several small proteins that may play a role in biofilm maturation.  Binds to and represses the operator of the ycgZ-ymgA-ariR-ymgC operon and also regulates ynaK.  Binding is antagonized by BluF upon blue light (470 nm) irradiation.  Blue light may increase the affinity of BluF for BluR, allowing it to be released from its operator.
What are the official names of this protein?
HTH-type transcriptional repressor BluR.