PharMolix/UniProtQA huggingface dataset:
Protein: PR39A_ARATH
Sequence: MGDSEAMVSEGYTSAPYGDYNASAATVESTGQETAPIVDASHSVNNDSLVNGTAPVENGSATDNVAVTAPAAEHGDNTGSTLSTEEERLWNIVRANSLEFNAWTALIDETERIAQDNIAKIRKVYDAFLAEFPLCYGYWKKFADHEARVGAMDKVVEVYERAVLGVTYSVDIWLHYCTFAINTYGDPETIRRLFERALVYVGTDFLSSPLWDKYIEYEYMQQDWSRVALIYTRILENPIQNLDRYFSSFKELAETRPLSELRSAEESAAAAVAVAGDASESAASESGEKADEGRSQVDGSTEQSPKLESASSTEPEELKKYVGIREAMYIKSKEFESKIIGYEMAIRRPYFHVRPLNVAELENWHNYLDFIERDGDFNKVVKLYERCVVTCANYPEYWIRYVTNMEASGSADLAENALARATQVFVKKQPEIHLFAARLKEQNGDIAGARAAYQLVHSEISPGLLEAVIKHANMEYRLGNLDDAFSLYEQVIAVEKGKEHSTILPLLYAQYSRFSYLVSRDAEKARRIIVEALDHVQPSKPLMEALIHFEAIQPPPREIDYLEPLVEKVIKPDADAQNIASSTEREELSLIYIEFLGIFGDVKSIKKAEDQHVKLFYPHRSTSELKKRSADDFLASDRTKMAKTYNGTPPAQPVSNAYPNAQAQWSGGYAAQPQTWPPAQAAPAQPQQWNPAYGQQAAYGAYGGYPAGYTAPQAPTPVPQAAAYGAYPAQTYPTQSYAPPVAAAAPAAAPVQQPAAAVAPQAYYNTYY
What is the function of this protein?
Involved in pre-mRNA splicing (PubMed:28971960).  Involved in the determination of flowering time probably via the modulation of flowering associated genes (e. g.  FLC, FT and SOC1) expression (PubMed:17380304).
What are the official names of this protein?
Pre-mRNA-processing factor 39-1, AtPRP39-1, PRP39 homolog A, Pre-mRNA-processing factor 39a.
What is the protein family that this protein belongs to?
Belongs to the PRP39 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YGAM_ECOL6
Sequence: MFNRPNRNDVDDGVQDIQNDVNQLADSLESVLKSWGSDAKGEAEAARSKAQALLKETRARMHGRTRVQQAARDAVGCADSFVRERPWCSVGTAAAVGIFIGALLSMRKS
What are the official names of this protein?
Uncharacterized protein YgaM.
What is the protein family that this protein belongs to?
Belongs to the ElaB/YgaM/YqjD family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: YM247_YEAST
Sequence: MAHKCASAKLLSGIMALLFNGKSLLRPICLHVHNHLVSNSDTNIVWP
What are the official names of this protein?
Uncharacterized protein YMR247W-A.
Protein: NU4M_CROAD
Sequence: PIAGSMVLAAILLKLGGYGIIRMMQILPTTKTDLFLPFIVLALWGAILANLTCLQQTDLKSLIAYSSISHMGLVVAAIIIQTPWGLSGAMALMIAHGFTSSALFCLANTTYERTHTRILILTRGFHNILPMATTWWLVTNLMNIAIPPSMNFTGELLIMSALFNWCPTTIIMLGLSMLITASYSLHMFLSTQMGPTMLNNQTEPMHSREHLLIALHLAPLLMISLKPELVI
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: FINC_BOVIN
Sequence: MLGGPGPGLLLLLAVLSLGTAVPSAGASKSRRQAQQIVQPQSPLTVSQSKPGCYDNGKHYQINQQWERTYLGSALVCTCYGGSRGFNCESKPEPEETCFDKYTGNTYRVGDTYERPKDSMIWDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDQAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSLQTTSAGSGSFTDVRTAIYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPFTYNGKTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCVAYSQLRDQCIVDGITYNVNDTFHKRHEEGHMLNCTCFGQGRGRWKCDPVDQCQDSETRTFYQIGDSWEKYLQGVRYQCYCYGRGIGEWACQPLQTYPDTSGPVQVIITETPSQPNSHPIQWSAPESSHISKYILRWKPKNSPDRWKEATIPGHLNSYTIKGLRPGVVYEGQLISVQHYGQREVTRFDFTTTSTSPAVTSNTVTGETTPLSPVVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYTVNVYEISEEGEQNLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPRAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVFIQQETTGVPRSDKVPPPRDLQFVEVTDVKITIMWTPPESPVTGYRVDVIPVNLPGEHGQRLPVSRNTFAEVTGLSPGVTYHFKVFAVNQGRESKPLTAQQATKLDAPTNLQFINETDTTVIVTWTPPRARIVGYRLTVGLTRGGQPKQYNVGPAASQYPLRNLQPGSEYAVSLVAVKGNQQSPRVTGVFTTLQPLGSIPHYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSESGSIVVSGLTPGVEYVYTISVLRDGQERDAPIVKKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGYSLEEVVHADQSSCTFENLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNVGPDTMRVTWAPPSSIELTNLLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYLVSVSSVYEQHESIPLRGRQKTALDSPSGIDFSDITANSFTVHWIAPRATITGYRIRHHPENMGGRPREDRVPPSRNSITLTNLNPGTEYVVSIVALNSKEESLPLVGQQSTVSDVPRDLEVIAATPTSLLISWDAPAVTVRYYRITYGETGGSSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPVSINYRTEIDKPSQMQVTDVQDNSISVRWLPSSSPVTGYRVTTAPKNGPGPSKTKTVGPDQTEMTIEGLQPTVEYVVSVYAQNQNGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEETAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTTIPAPTNLKFTQVTPTSLTAQWTAPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAIPANGQTPIQRTIRPDVRSYTITGLQPGTDYKIHLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIQVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFITNPGYDTGNGIQLPGTSGQQPSLGQQMIFEEHGFRRTTPPTTATPVRHRPRPYPPNVNEEIQIGHVPRGDVDHHLYPHVVGLNPNASTGQEALSQTTISWTPFQESSEYIISCHPVGIDEEPLQFRVPGTSASATLTGLTRGATYNIIVEAVKDQQRQKVREEVVTVGNSVDQGLSQPTDDSCFDPYTVSHYAIGEEWERLSDSGFKLSCQCLGFGSGHFRCDSSKWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGAEPGNEGSTAHSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE
What is the function of this protein?
Binds fibronectin and induces fibril formation.  This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties.  Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis.  Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.
What are the official names of this protein?
Fibronectin, FN.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: NAC23_ORYSJ
Sequence: MAMTPQLAFSRMPPGFRFQPTDEQLVVDYLQRRTAAQPCVTPDITDIDVYNVDPWQLPAMAMYGSDHDRYFFTMAAREAQARRTTPSGFWKPTGTKKTIFVVAGGHEVPTAVKRRFVFYLGHHQPSGSNNNNKTSWIMHEYRLMNSPRAAVPSSSSVNRLPTDDLTEEMVLCRISNKDLPKPPFIHNSLLQFSSVGLNGDGYNYLILDHLEPPAMEYPNVGIGNVDDAAAGTDDPGDLDEEIDDSMQRNHGG
What is the function of this protein?
Transcription factor involved in the regulation of seed size (By similarity).  Binds to DNA-specific sequences of CLPD1 and OAT promoters in vitro (PubMed:18813954).
What are the official names of this protein?
NAC domain-containing protein 23, ONAC023, OsNAC6, Protein THERMOSENSITIVE MALE STERILITY 5.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: PCKA_CAMJR
Sequence: MKKFDKLGLDNIKEIFHNLSYDELNAHEKANNEGLSTDNDTFCVDTGIFTGRSPKDKYFVKQDPSSKYIAWGKVNQPITKELFDKLLTKAKQELSGKKIYVQDVFCGASLQSRKAVRFVTEIAWQAHFVKNMFIRPSQEELENFKADFIVYNACKCINEDYKQDGLNSEVFVIFNVEENIAVIGGTWYGGEMKKGIFSMMNYWLPLENKLSMHCSANVGEKDDVALFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDEGVFNFEGGCYAKTINLNPEHEPEIYGAIKRNALLENVVLRADKSVDYADASKTENTRVSYPIEHIENHEPSLKAGHPKNIIFLSADAFGILPPVSKLSKEQAMYYFLSGYTAKVAGTERGITEPQATFSACFGEPFMPLHPTVYARLLGEKIEKHEVNVYLVNTGWSGGSYSVGKRMSIKATRACINAILDGSITKCEFENFEVFDLAIPKALEGVESVLLNPINTWLDKNAYIATRDKLAHMFIQNFKRYEDVKEGIEFSKFGPKI
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCAR3_HUMAN
Sequence: MAAGKFASLPRNMPVNHQFPLASSMDLLSSRSPLAEHRPDAYQDVSIHGTLPRKKKGPPPIRSCDDFSHMGTLPHSKSPRQNSPVTQDGIQESPWQDRHGETFTFRDPHLLDPTVEYVKFSKERHIMDRTPEKLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLAQHFKINRTVLRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPISQQSGAIIFQPINRTVPLRCLEEHYGTSPGQAREGSLTKGRPDVAKRLSLTMGGVQAREQNLPRGNLLRNKEKSGSQPACLDHMQDRRALSLKAHQSESYLPIGCKLPPQSSGVDTSPCPNSPVFRTGSEPALSPAVVRRVSSDARAGEALRGSDSQLCPKPPPKPCKVPFLKVPSSPSAWLNSEANYCELNPAFATGCGRGAKLPSCAQGSHTELLTAKQNEAPGPRNSGVNYLILDDDDRERPWEPAAAQMEKGQWDKGEFVTPLLETVSSFRPNEFESKFLPPENKPLETAMLKRAKELFTNNDPKVIAQHVLSMDCRVARILGVSEEMRRNMGVSSGLELITLPHGHQLRLDIIERHNTMAIGIAVDILGCTGTLEDRAATLSKIIQVAVELKDSMGDLYSFSALMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKLLHEGRESTCVPPNNVSVPLLMPLVTLMERQAVTFEGTDMWEKNDQSCEIMLNHLATARFMAEAADSYRMNAERILAGFQPDEEMNEICKTEFQMRLLWGSKGAQVNQTERYEKFNQILTALSRKLEPPPVKQAEL
What is the function of this protein?
Acts as an adapter protein downstream of several growth factor receptors to promote cell proliferation, migration, and redistribution of actin fibers (PubMed:24216110).  Specifically involved in INS/insulin signaling pathway by mediating MAPK1/ERK2-MAPK3/ERK1 activation and DNA synthesis (PubMed:24216110).  Promotes insulin-mediated membrane ruffling (By similarity).  In response to vasoconstrictor peptide EDN1, involved in the activation of RAP1 downstream of PTK2B via interaction with phosphorylated BCAR1 (PubMed:19086031).  Inhibits cell migration and invasion via regulation of TGFB-mediated matrix digestion, actin filament rearrangement, and inhibition of invadopodia activity (By similarity).  May inhibit TGFB-SMAD signaling, via facilitating BCAR1 and SMAD2 and/or SMAD3 interaction (By similarity).  Regulates EGF-induced DNA synthesis (PubMed:18722344).  Required for the maintenance of ocular lens morphology and structural integrity, potentially via regulation of focal adhesion complex signaling (By similarity).  Acts upstream of PTPRA to regulate the localization of BCAR1 and PTPRA to focal adhesions, via regulation of SRC-mediated phosphorylation of PTPRA (By similarity).  Positively regulates integrin-induced tyrosine phosphorylation of BCAR1 (By similarity).  Acts as a guanine nucleotide exchange factor (GEF) for small GTPases RALA, RAP1A and RRAS (By similarity).  However, in a contrasting study, lacks GEF activity towards RAP1 (PubMed:22081014).
What are the official names of this protein?
Breast cancer anti-estrogen resistance protein 3, Novel SH2-containing protein 2, SH2 domain-containing protein 3B.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, focal adhesion. Note=Localization to focal adhesions depends on interaction with PTPRA.
Protein: FALX6_LITFA
Sequence: MASLKKSLFLVLFLGFVSLSICEEEKRENEGNENEEEDENHEEGSEEKRGLLDLAKHVIGIASKLGKRSEEKRYHPFGKRSEEKRYHPFGKRSEEKRYPPIGK
What is the function of this protein?
Fallaxidin-3. 1 shows antibacterial activity against the Gram-positive bacteria E. faecalis (MIC=100 uM) and L. lactis (MIC=100 uM).  No antibacterial activity against the Gram-positive bacteria B. cereus, L. innocua, M. luteus, S. epidermidis, S. uberis and S. aureus, or the Gram-negative bacteria E. cloacae and E. coli.
What are the official names of this protein?
Preprofallaxidin-6.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MURI_MYCPA
Sequence: MSSALAPVGIFDSGVGGLTVARAIIDQLPDEHIIYVGDTGHGPYGPLSIPEVRAHALAIGDDLVGRGVKALVIACNTASAACLRDARERYEVPVVEVILPAVRRAVATTRNGRIGVIGTQATINSHAYQDAFAAARDTEITAVACPRFVDFVERGVTSGRQVLGLAEGYLEPLQRAQVDTLVLGCTHYPLLSGLIQLAMGDNVTLVSSAEETAKEVLRVLAERDLLHPHPDDPRAAGPSRVFEATGDPEAFTRLAARFLGPAVSGVRPVHHVRID
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: SYP_METCA
Sequence: MRTSQFPLNTLKEIPSDAEIVSHQLMLRAGLIRKLAAGLYTWLPLGLKVLRRVERVVREEMDRAGALEVLMPVVQPAELWQESGRWEQYGPELARLHDRHDRAFCLGPTHEEIITDLARNELKSYRQLPVNFYQIQTKFRDEIRPRFGVMRAREFVMKDAYSFHLDQESLAQTYDAMYVAYSNIFSRLGLRFRPVLADTGAIGGSHSHEFHVLADSGEDAIAFSTVSDYAANVEQAEALAPTAPRPAPTAALLKVETPGKKSIAEVSEFLGVPPHQILKTVAVMQTIVDDDGLDRDMFVTVLLRGDHELNEVKLGKVLGRFRFASEDEIERHMGCRPGYIGPLNLPAGTAVGPVYADRAVAVMSDFVCGANEAGYHFSGVNWERDLPLPQDEYLCDLRNVVEGDPSPDGLGTLRIARGIEVGHIFQLGTKYSAALNATVLNEEGRSQVMLMGCYGIGVSRVVAAAIEQNHDERGIVWPEALAPFQVALCPINMQTSARVRTTAERLYAELSAAGFEVLYDDRKVRPGVMFADMELIGIPHRIVISERGLDSGALEYKGRRDADNQSIGIDGVIEFLRERSESR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KU_METSB
Sequence: MAPRSFWKGYLKLSLVTCPVVMAPAKSEKEKLRFHTLNRATGNRVQSRYIDSVSGKPVDSADQVKGFPRDDQSYVMLEDEELDSVALESARTIDIELFAPADSIDWIWYDAPHYLTPGDEVGEEAFAVIREAMKATKMVGISRLVLYRRERAVLLEPRGKGIILWTLRYGDEVRDPKLYFDAIKDQKPVPELLSLVNRLIEERVKPWSPEMASDPVQDRLRDIIEAKKTPPAKKTKAEEKTGKGSAESNVIDIMDALRKSLGPAAKKPKGR
What is the function of this protein?
With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity.  Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA.  Recruits and stimulates the ligase activity of LigD.
What are the official names of this protein?
Non-homologous end joining protein Ku.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic Ku family.
Protein: PHRK_BACSU
Sequence: MKKLVLCVSILAVILSGVALTQLSTDSPSNIQVAERPVGG
What is the function of this protein?
Signaling molecule involved in the regulation of genetic competence development (PubMed:16816200).  Secreted during production, but the mature peptide acts intracellularly, indicating that it needs to be imported into the cell to function (By similarity).  Stimulates expression of the genes controlled by ComA, a transcriptional factor that regulates the development of genetic competence (PubMed:16816200).  Acts by inhibiting RapK, which regulates the activity of ComA (PubMed:16816200).
What are the official names of this protein?
RapK inhibitor.
What is the protein family that this protein belongs to?
Belongs to the Phr family.
Protein: PDAD_METBU
Sequence: MIPKKAFVVKGTGVHKDKLASFELALRDAGIEKFNLVTVSSILPPNCSIVSRKEGLEELAPGQIVYCVMAKNQTNEPERMIAAAIGNAVPVDSNDYGYISEHHSFGEDERTAGIYAEDLAATMLATTLGIEFDADSAWGERERVYKASGHIFDTVHYCRCVKGDENGLWTTVVVSMVFVL
What are the official names of this protein?
Pyruvoyl-dependent arginine decarboxylase, PvlArgDC.
What is the protein family that this protein belongs to?
Belongs to the PdaD family.
Protein: RL3_HALMA
Sequence: MPQPSRPRKGSLGFGPRKRSTSETPRFNSWPSDDGQPGVQGFAGYKAGMTHVVLVNDEPNSPREGMEETVPVTVIETPPMRAVALRAYEDTPYGQRPLTEVWTDEFHSELDRTLDVPEDHDPDAAEEQIRDAHEAGDLGDLRLITHTVPDAVPSVPKKKPDVMETRVGGGSVSDRLDHALDIVEDGGEHAMNDIFRAGEYADVAGVTKGKGTQGPVKRWGVQKRKGKHARQGWRRRIGNLGPWNPSRVRSTVPQQGQTGYHQRTELNKRLIDIGEGDEPTVDGGFVNYGEVDGPYTLVKGSVPGPDKRLVRFRPAVRPNDQPRLDPEVRYVSNESNQG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3, Hl1, Hmal3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: ACCD_BART1
Sequence: MNWITNYVRPKINSILGRREIPENLWIKDPTSGEMIFHKDLEANQFVAPNSGYHMRISAKNRLVHFFDDGVYTALENPKVVTDPLKFRDEKRYIDRLKDYRSKLGVDDNILSARGTIEGLPIIATVQDFAFMGGSLGMASGEAIVKAFDTAIAEKCPLVLFAASGGARMQEGTLSLMQMPRTTVAIEMLKEAKLPYIVVLTNPTTGGVTASYAMLGDIHIAEPGAMIGFAGPRVIQQTIRETLPEGFQSSEYLLEHGMIDMVVSRLEMKTTIARLLRLMMKRPAVVTPSPPSPTDSQTSLSKTKAA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CM3A_CONPB
Sequence: HECCKKGFCDPGCDCCDQ
What are the official names of this protein?
Conotoxin pc3a.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DP2L_METM6
Sequence: MLHVSASKGMAEYFKNILDNVTELYTLADDCRKSGYDVTDHVEIPLAKDMADRVEGIVGPKNVAERIRELVSDLGKEPAALEIAKEIVEGKFGEFGREVGAEQAVRTALAVITEGIVAAPLEGIAHVKIKKNNDGSEYLAIYFAGPIRSAGGTAQALAVLVGDYVRKNMGLDKFKPTEDEVERYGEEVDLYQSEVTTFQYQPKAEEIRVAVRNISVEITGEATDDVEVSGHRDLPRVETNQIRGGALLALVEGVLLKAPKILRHVDKLGIEGWDWLKELKSKKEEVIEEIEEEKDDFNYEEEEDLSQYEDYEVEAVTKFIGEVIAGRPVFSHPSKKGGFRLRYGRSRNTGFATDGFHPAIMYLVDDFMAVGTQLKTERPGKATCVVPVDSIEGPIVKLNDKSVLKIDTVEKAKQYRDDVEEILFLGDILVNYGDFLENNHTILPSSWCVEWYEKILKSENLEYTKEFIENPDQKEAVTYAKLTKTPLHPKYTYFWHDISKDNINVLRNWLIGGKYNENNDSWELTYNLEDSEIATSKRYLELIGCPHTVTAETVEIFEYYPLLYSLGYDFDKKQDIVEDIGEKLQNTKNNMHFINTIAPFEIRRNAYIYVGARMGRPEKAASRKMKPPVNGLFPIGNAGALVRLINKAVEEGKTDEIEISNVKCSCGNVSLYRTCPFCGSSVEPSGPSRIKLPIKEYWYKALENLKINKAGDVKCIKGMTSKDKIIEPLEKAILRAKNDIFVFKDGTTRFDCTDVPVTHFRPVEIHVGIEKLKFLGYLKDIHGNPLENENQVLELKVQDVIVPESCMDYFFNVSKFIDDLLEKYYKKDRFYNVNKREELVGHLIIGMAPHTSAGMVGRIIGYSYANVGYAHPYFHASKRRNCDGDEDAFFLLLDAFMNFSKRFLPDKRGGQMDAPLVLTTILDPKEVDGEVHNMDSMWEYPLEFYEKSLEGIAPKEIKKIMQTVEDRLDKDSQYEGIGYTHETLKIDEGPLVCAYKTLGSMMEKTSAQLAVAKKIRATDERDVAEKVIQSHFVPDLIGNLRAFSRQGVRCKCGAKYRRMPLKGVCRKCGSRLILTVSKGAVEKYMDVSQTMAEKYNASDYIKQRLEIIRSGIDSLFVNDKRKQVKIEDFFK
What is the function of this protein?
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction.  Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase II large subunit, Pol II, Exodeoxyribonuclease large subunit.
What is the protein family that this protein belongs to?
Belongs to the archaeal DNA polymerase II family.
Protein: DPS_YERPN
Sequence: MSTAKLVKTKPSELLYTRNDVEEHVKVATIKRLNQMVIQFIDLSLITKQAHWNMRGANFVAVHEMLDGFRTALTDHLDTFAERAVQLGGVALGTAQVINDKTPLKSYPTNIHSVQEHLKALAERYAIVANDIRKAITEVEDENSADMFTAASRDLDKFLWFIESNIE
What is the function of this protein?
During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages.  It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction.  One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
What are the official names of this protein?
DNA protection during starvation protein.
What is the protein family that this protein belongs to?
Belongs to the Dps family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_NITHX
Sequence: MSRKYFGTDGIRGRANGLITPELAMKVGQAAGLVFQRGEYRHRVVIGKDTRLSGYMIEYALVAGFTSVGMDVLLLGPMPTPAVAMLTKSMRADLGVMISASHNLFEDNGIKMFGPRGFKLSDAVEKQIEQLLDENLDKKLAQSTGLGRARRIDGVHDRYIEFAKRTLPRELSLDGLRVVVDCANGAAYRVVPEALWELGADVVPISVEPDGFNINKECGSTAPEALCRKVREMRADIGIALDGDADRVIIVDERGHVVDGDQLLAVIAESWKEDGRLTKPGIVATVMSNLGLERFLEGQELSLVRTPVGDRYVLEQMLKQGYNLGGEQSGHIILSDYATTGDGFVSALQVLAVVQKLGRPVSEVCHKFEPLPQILKNYRYRSGKPLDRAEVKSAITAGEKRLNGHGRLLVRSSGTEPVIRVMGEGDDRILVEDVVDTIVSALGGPAAA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RS15_DEHM1
Sequence: MDKQEKSLIINEFKKSENDTGSTEVQVALLTARIHQLTTHMIANKHDFHTKRSLLTLVGRRRRLLSYMRNNNGAGYQELIANLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: PURL_NITSB
Sequence: MENIEEILKAHKLTMEDYEHIKKILGREPNLVEIGIFSAMWSEHCSYKSSKKYLKGFPTEAPWVIQGPGENAGVIDIGDGMAAVFKMESHNHPSFIEPYQGAATGVGGILRDVFTMGARPVANLNALRFGDVKREDEVGAHQRYLVRGVVAGIGGYGNCVGVPTIGGEVSFDECYNGNILVNAFSLGICKKDEIFYGRAEGVGNPVIYVGSKTGRDGLGGAVMSSDSFTEETKKLRPTVQVGDPFTEKLLLEACLELFKTDYVVGIQDMGAAGLTSSSFEMAGRAGSGMKMYLDKVPMREEGMTPYELMLSESQERMLICAKKGTEEKVLEIFRKWDLDAEIIGEVTDTGVMELYWHGEKVAEVPVAPVSEEAPELDRPTKRPEYLAYIKETSIDTVPHVEDQEAFEKLLGSLEVVNKAWVYEQYDSMVQTNTVKHPGTLDASVIRVKENGKAIAMSSKCNPRYCYIDPKGGAAAAVMAAGRNVAMSGARPLAITDCLNYGNPENPEVMWQFAQGTEGIKEACRALNTPVVSGNVSLYNETNGVSVYPTPTIAMVGLNDDANKVVPSYFQETNDVVYIIGDTEKEFGGSLYLKELFGKVAGELPKIDYEKELRLWNFVIEANNRGLLKAAKDVGVGGIAIALAKMAALGNKGFLGNFCFEDSREIFSETFSRALVEIDPKNMHALEELANEIGIHATPLGTVGGNRFQLCDIDMEMEKLKDIYFNTFKREIERDL
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_SHEPW
Sequence: MLERAPVVTVDGPSGAGKGTISQLLAEKLGYKLLDSGAIYRVLALAAIHHNVELDNEESLTLLAAHLDVQFITGNESKGIKVVLEGEDVSTTIRSQECSNAASKVAAFPRVREALLRRQRAFAEAPGLIADGRDMGTVVFPATPAKLFLTASAEERAQRRYNQLQDNGFDVKIDQLLSEIKERDDRDMNRSVAPLVPAEDALVIDTTNISIEDVLAMALTHIHKSFQVPA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.