PharMolix/UniProtQA huggingface dataset:
Protein: NAA25_DROME
Sequence: MAQQQGMDSALFERRLRPVYDNLEVGNNRKALQESEKLLRKHPNLLCARALKGLSLLRLGRYDESHGCLQTVAEEKPTDDSTLQVLSFCYREMEQLDKIVELYQHAVKQNPGNEELLAHLFISHVRVEDYKAQQAVALQLYKAQPKNAYYFWSVISVVFQGIRGPESALPEKRKIYLGLAQRMVDKHIKEGKMETEQEAFLYLHILKLQNKYQEAWEFLTGELCAKLYPGAPVSMKFELLKELGNWRELNELLQQLLDADRDRWDFYKEYIQSSFELLKLTPQGVENGDKDSLARCQEFLQRIIDSSERKKRGPYLARLELHQRMRAEQLPAEKLIGDFDEMVIEYFRLFGDKSCCTHDIALFLPSISMNQRQALASKLLLESGVTSTSLPKNKEQLQKHLCALQISRMCGSHMDLPADHLLAFYTALKLHYEHGRTTFGKKLLATEMGPSDAYALLAANVMYDLSRRENKSDHLFEALCLLQYVLRNSTSNFHVKLLSLKIYHLFGCQVGAQEMYEYLDIKQIQLDSMGYVHCQLLALGGRFSGNRNVYDATLKFFTNSYKERLEYIALTYRFCTFSKMEEFMNFKERLTNSLQYVACSVEAQICDLVSCYGNITQNLSAYVAMSIEPAEDRIAWHELSDNRDLGAIIRWDPLHEVDAAEERRESFDQEVEVLQVRSLMLRLFASFIDLYHGAGLKDSPAGAETATLELLRESWTGLFQRLRVMNYKPLAQKFLVNLLPTRLHLLLDMPYERFFDDLAQLVLDLQSGSAKLAEQCKRVGDNVIATMELCVQTINESNESNGIDGLWKRRGQQQKVAASLEMLSLYAFLLSVLNDKLQVSSKTKTKKKPVENKVDGPQPISEKERSQMLQELMRQLKHKFEACDTAIRSWKAPVLPRDLSSFMSDMSLKPEVEATLIGDVSATFKDSHELMVTELRNLLKDKIRMVAK
What is the function of this protein?
Non-catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of proteins beginning with Met-Asp or Met-Glu (By similarity).  Has 2 roles in the larval immune response: required both for the phagocytic degradation of internalized bacteria and for the induction of Defensin in the fat body.  Within the phagocytic blood cells, has a role in detection of infection and activation of the humoral immune response.
What are the official names of this protein?
Phagocyte signaling-impaired protein, N-terminal acetyltransferase B complex subunit MDM20 homolog, N-terminal acetyltransferase B complex subunit NAA25 homolog.
What is the protein family that this protein belongs to?
Belongs to the MDM20/NAA25 family.
Protein: ADE_ALBFT
Sequence: MTIKPVSQERLPELLRTIPKAELHIHIEGSLEPELMFALAQRNGVSIPYPDVASLRAAYVFDNLQSFLDIYHAGTLVLRTEQDFYDMTHAYLARAAADNVLHAEIFFDPQTHTAHGVSADVVINGLYRACVDARVEFDMNASLILCFLRHLSEQEAFECLEQALPHLDKLVGVGLASSEMGHPPEKFARVFARARELGLRLVAHAGEEGPPAYIWSALDVLKVERIDHGVQAVQDPLLMARLARDRIALTVCPLSNLKLRVFPTLAAHNLGRLLEAGIVATVNSDDPSYFGGYINQNFTQTFAALGLTAQHAYQLAHNSFEASFIDDRLKRQYFDRLAGVFETFE
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
Protein: PSTB2_NOSS1
Sequence: MNQQLVPAIKVKDLSFYYNTSKAIEGISMDIYRNKVTAIIGPSGCGKSTFIKTLNRISELEGPVKVEGVVDFFGQNIYDPRININRLRRQIGMVFQRPNPFPMSIYENVAYGVRISAKLPQADLDEIVESALKGAALWQEVKDKLNKSALGLSGGQQQRLCIARALAIKPKVLLMDEPCSALDPIATMKVEELIHSLRSELTIAIVTHNMQQATRVSDFTAFFSTDESRIGQMVEFGVTTQIFSNPLDSRTRDYVSGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 2, ABC phosphate transporter 2, Phosphate-transporting ATPase 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PTH_RALSO
Sequence: MIKLIVGLGNPGAEYAATRHNAGFWLVDQLARMGHVTLRNETRFHGYAARATLWSHEVWLLQPQTFMNRSGLATVALARFYKILPDEILVVHDELDLLPGAVKLKLGGGSGGHNGLKDIAAHLTTQQFWRLRVGIGHPRNLLPPGTAPSGQHDVANFVLKAPRREEQELIDRAIDRSLDALPDLVAGNAERAMMRLHTTG
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRAAH_PARP8
Sequence: MNFATADLCDAHEDQLTAGTLRVLDPVFSRFGRASRFGGEAVTLKVFEDNTLVRATLEEKGVARVLVVDGGGSLRCALVGGNLGKLGEKNGWAGIVVFGCVRDTLELNECNLGIIALATHPQRSQKRGGGERDVSLRLPGSVVRPGEWIYADSDGVLVSSAPLV
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: YDER_BACSU
Sequence: MANGNKQAGQRISPSLTLLLATACGIIVANLYYAQPLVGLISKAIGLSPSGAGLIVTLTQIGYVAGLLFLVPLGDIIENKKLIVVSLLLSAAALTLTAFVKHGTLFLAAAFFVGLGSIAAQVLVPFASYLASDAARGRVVGNVMSGLLLGIMLSRPISSLVADIWGWNAIFALSAVVSVILAIVLSKVLPARKPTANTNYTALLGSMWKLLRTTPVLRRRAIYHAFVFGAFSLFWTTVPLLLSGPDFHFSQKAIALYALVGIAGAVTAPIGGRLADRGLTRLATGIALGVVVVSLLLPLMIQSSSPVGITVLVAAAILLDMGVSANLVLSQRAIFSLAPEIRSRLNGLFMAIFFLGGAIGSSIGGWAYASGGWSTALWIGIAFPVIALLYFITEK
What are the official names of this protein?
Uncharacterized MFS-type transporter YdeR.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: E310_ADE06
Sequence: MIPRVLILLTLVALFCACSTLAAVAHIEVDCIPPFTVYLLYGFVTLILICSLVTVVIAFIQFIDWICVRIAYLRHHPQYRDRTIADLLRIL
What is the function of this protein?
Down-regulates the EGF receptor.
What are the official names of this protein?
Early E3B 10.4 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E3B family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: NHLC3_HUMAN
Sequence: MARFWVCVAGAGFFLAFLVLHSRFCGSPVLRNFTFAVSWRTEKILYRLDVGWPKHPEYFTGTTFCVAVDSLNGLVYIGQRGDNIPKILVFTEDGYFLRAWNYTVDTPHGIFAASTLYEQSVWITDVGSGFFGHTVKKYSSFGDLVQVLGTPGKKGTSLNPLQFDNPAELYVEDTGDIYIVDGDGGLNNRLIKLSQDFMILWLHGENGTGPAKFNIPHSVTLDSAGRVWVADRGNKRIQVFDKDTGEWLGAWNNCFTEEGPSSVRFTPDGKYLIVAQLNLSRLSVVAAPPVGSIGECSVISTIQLADQVLPHLLEVDRKTGAVYVAEIGAKQVQKYVPLNSYVPSFGS
What are the official names of this protein?
NHL repeat-containing protein 3.
Protein: SIM15_PONAB
Sequence: MFDIKAWAEYVVEWAAKDPYGFLTTVILALTPLFLASAVLSWKLAKMIEAREKEQKKKQKRQENIAKAKRLKKD
What are the official names of this protein?
Small integral membrane protein 15.
What is the protein family that this protein belongs to?
Belongs to the SMIM15 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MOAA_SYNWW
Sequence: MLDKHERNINYMRISLTDRCNLRCRYCMPETGVDNLTHYSILSLEEMARLVRIASELGIQKIRLTGGEPLVRRNVPQLISYIAQIPRIDDIALTTNGTLFAALAEELKTAGLNRINFSLDSLVPEKFKYITRRGDLSKVKEAIFKALELDMHPVKINMVVIRGFNDDEIIDFVELARKYPLHVRFIEFMPVGDLLFWKKDRMMPAQDIKAYIEESYVLTPQKNILGNGPARYYSLEGGEGSLGFISPMSNHFCGECNRIRLTAEGGLRGCLYDKREVNLKTALKNGSSDEEIKELFIWAIKAKPARHHMNNGWGEENKRKMYQIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: ACEK_ECO27
Sequence: MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAAFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDLPLRLRWQNKSRDIHYIVRHLTETLGTDNLAESHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDRFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMALLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPLPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSVRFV
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S10A4_CANLF
Sequence: MTFPLEKALDVMVSTFHKYSGKEGDKFKLNRSELKELLMRELPSFLGKRTDEAAFQKLMSNLDSNRDNEVDFQEYCVFLSCVAMMCNEFFEGFPDKQPRKK
What is the function of this protein?
Calcium-binding protein that plays a role in various cellular processes including motility, angiogenesis, cell differentiation, apoptosis, and autophagy.  Increases cell motility and invasiveness by interacting with non-muscle myosin heavy chain (NMMHC) IIA/MYH9 (By similarity).  Mechanistically, promotes filament depolymerization and increases the amount of soluble myosin-IIA, resulting in the formation of stable protrusions facilitating chemotaxis (By similarity).  Modulates also the pro-apoptotic function of TP53 by binding to its C-terminal transactivation domain within the nucleus and reducing its protein levels (By similarity).  Within the extracellular space, stimulates cytokine production including granulocyte colony-stimulating factor and CCL24 from T-lymphocytes (By similarity).  In addition, stimulates T-lymphocyte chemotaxis by acting as a chemoattractant complex with PGLYRP1 that promotes lymphocyte migration via CCR5 and CXCR3 receptors (By similarity).
What are the official names of this protein?
Protein S100-A4, Metastasin, S100 calcium-binding protein A4.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.
What are the subcellular locations of this protein?
Secreted. Nucleus. Cytoplasm.
Protein: GNRHR_TRIVU
Sequence: MANRAYLEQKQTQCSIINSSFSMTHRDLPTLTLSGKIRVMVTFFLFLVSTAFNASFLMKLQRQTQKKEEVKKLTRMKVLLKHLTLANLLETVIVMPLDGIWNVTVQWYAGEFLCKALSYLKLFSMYAPAFMMVVISLDRFLAITRPLAVKSNTKVGQSLIAVAWFLSIVLAGPQLYIFRMIYVEDISGQTGNFSQCVTHCSFPEWWQEAFYNLLTFSCLFIGPLLIMLVCNAKIIFTLTQVLHQDPHELQLNRSKNNIPRARLRTLKMTVAFATLFTICWTPYYVLGIWYWFDPEMLNRVSDPVNHFFFLFGLLNPCFDPLIYGYFSL
What is the function of this protein?
Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH).  This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).
What are the official names of this protein?
Gonadotropin-releasing hormone receptor, GnRH receptor, GnRH-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y016_HIS1I
Sequence: MNVEIGQSDSGKDYVLTGKDNKILSYQTPDLQYTTLGKFIIYRLLHDRDVKILITGKGKTTGTGKTTLAIVLAKWINEVRNEIFNLNEQWHAKDYSFMDVWEYLEKYREAKPGDPLITDELEYMADKRRHMTNENVKFSQAWSILRYKNAVTLGTAPGLSDLEKRVIETADIWINVVHVGKANTYYLTFDDFEWEPIYRRLRQGQFKESICWDELNDENYQWLKQEKENLGVPGLDDNGQENQLEQSDLNKREREVKNSTVKEMLKLLYENSLHDSITQSDIADVCGVSQQQVSNLKRELEKDNEIPT
What are the official names of this protein?
Uncharacterized protein ORF16.
Protein: NUBP1_DANRE
Sequence: MADVPNDAPEHCPGTSSDQAGKSSACQGCPNQSICASGATKAPDPAIEEIKQKMTSVKHKILVLSGKGGVGKSTFSAHLSHALASDSSKEVALLDVDICGPSIPKIMGLEGEQVHQSGSGWSPVYVEDNLAVMSIGFLLSSPDDAVIWRGPKKNGMIKQFLRDVDWGEVDYLIVDTPPGTSDEHLSIVQYLSGAGIDGAVIITTPQEVSLQDVRKEIRFCKKVNLPILGVIENMSGFVCPKCKNTSQIFPPTTGGAQRMCEELNLPLLGRIPLDPRIGKSCDEGKSFLTEVPDSPAAAAYQSIVQKIRDYCASHSASDDSC
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The nubp1-nubp2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor nubp1, Nucleotide-binding protein 1, NBP 1.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRB_ACIBC
Sequence: MGKVNKTDREWQRELSPEEYRITRQKGTEPAFTGQYWNTKQHGTYVCRCCGAELFSSDAKYDSGCGWPSFFRPLNGSVIDEHEDLTHGMVRTEIVCHDCEAHLGHVFEDGPQPTGLRYCVNSASLQLKTQEKNDEETYP
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: OADB_KLEPN
Sequence: MESLNALIQGLGLMHLGAGQAIMLLVSLLLLWLAIAKKFEPLLLLPIGFGGLLSNIPEAGLALTALESLLAHRDPAQLAVIAAKLHCAPDVHAIKAALALALPSVQGQMESLAVDMGYSAGVLAIFYKVAIGSGIAPLVIFMGVGAMTDFGPLLANPRTLLLGAAAQFGIFATVLGALTLNYFGIISFTLPQAAAIGIIGGADGPTAIYLSGKLAPELLGAIAVAAYSYMALVPLIQPPIMKALTTDKERKIRMVQLRTVSKREKILFPAVLLLLVALLLPDAAPLLGMFCFGNLMRESGVVERLSDTVQNALINIVTIFLGLSVGAKLVADKFLQPQTLGILVLGVIAFCVGTAAGVLMAKLMNVFSRHKINPLIGSAGVSAVPMAARVSNKVGLEADGQNFLLMHAMGPNVAGVIGSAIAAGVMLKYVLAM
What is the function of this protein?
Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
What are the official names of this protein?
Oxaloacetate decarboxylase beta chain.
What is the protein family that this protein belongs to?
Belongs to the GcdB/MmdB/OadB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: P_MOUSE
Sequence: MRLENKDIRLASAVLEVELHQTSALSVPTCPDPGRLLTVKPATSNYKLGQADPCIPYAGEAAGKSVCVPEHTEFGSFLVKGSSSLKDLSFKEDTPLLWNSSQKKRSQLMPVHHPEFIATEGSWENGLTAWEQKCMLGKEVADLSALASSEKRDLAGSVHLRAQVSKLGCCVRWIKITGLFVFVVLCSILFSLYPDQGKFWQLLAVSPLENYSVNLSGHADSMILQLDLAGALMAGGPSGSGKEEHVVVVVTQTDAAGNRRRRPQQLTYNWTVLLNPRSEHVVVSRTFEIVSREAVSISIQASLQQTRLVPLLLAHQFLGASVEAQVASAVAILAGVYTLIIFEIVHRTLAAMLGALAALAALAVVGDRPSLTHVVEWIDFETLALLFGMMILVAVFSETGFFDYCAVKAYQLSRGRVWAMIFMLCLMAAILSAFLDNVTTMLLFTPVTIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVIIVSNQELRKMGLDFAGFTAHMFLGICLVLLVSFPLLRLLYWNKKLYNKEPSEIVELKHEIHVWRLTAQRISPASREETAVRGLLLEKVLALEHLLAQRLHTFHRQISQEDKNWETNIQELQRKHRISDRSLLVKCLTVLGFVISMFFLNSFVPGIHLDLGWIAILGAIWLLILADIHDFEIILHRVEWATLLFFAALFVLMEALTHLHLVEYVGEQTALLIKMVPEDQRFAAAIVLIVWVSALASSLIDNIPFTATMIPVLLNLSQDPEISLPALPLMYALALGACLGGNGTLIGASTNVVCAGIAEKHGYGFSFMEFFRLGFPVMLMSCTIGMCYLLIAHIVVGWN
What is the function of this protein?
Contributes to a melanosome-specific anion (chloride) current that modulates melanosomal pH for optimal tyrosinase activity required for melanogenesis and the melanosome maturation.  One of the components of the mammalian pigmentary system (By similarity).  May serve as a key control point at which color variation is determined.  Major determinant of eye color (Probable).  Seems to regulate the post-translational processing of tyrosinase, which catalyzes the limiting reaction in melanin synthesis (PubMed:12058062).
What are the official names of this protein?
P protein, Melanocyte-specific transporter protein, Pink-eyed dilution protein.
What is the protein family that this protein belongs to?
Belongs to the CitM (TC 2.A.11) transporter family.
What are the subcellular locations of this protein?
Melanosome membrane; Multi-pass membrane protein.
Protein: LDH1_ENTFA
Sequence: MTAAAGNKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIIDINVPKTEGDALDLSHALAFTSPKKIYAATYDDCHDADLVVLTAGAPQKPGETRLDLVHKNLKINKEIVTTIVDSGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFRQAIAELVDVDARNVHAYILGEHGDTEFPVWSHANVAGLQIYEWVKNNPDVDEEAMVNLFFNVRDAAYTIIEKKGATFYGIAVALARITKAILNDENSVLPLSVYLEGEYGQNDIYIGAPAIINRQGVKQVIEIPLTDAEQEKMEASASALKEVIETAFAKFEAEEAK
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase 1, L-LDH 1.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTE_ESCF3
Sequence: MDNFLALTLTGKKPVITEREINGVRWRWLGDGVLELTPLTPPQGALVISAGIHGNETAPVEMLDALLGAISHGEIPLRWRLLVIFGNPPALKQGKRYCHSDMNRMFGGRWQLFAESGETCRARELEQCLEDFFDQGKESVRWHLDLHTAIRGSLHPQFGVLPQRDIPWDEKFLTWLGTAGLEALVFHQAPGGTFTHFSARHFGALACTLELGKALPFGQNDLRQFAVTASAIAARVSGESVGVVRTPPIRYRVVSQITRHSPSFEMHMASDTLNFMPFKKGTLLAQDGEERFTVTHDVEYVLFPNPLVALGLRAGLMLEKIS
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: RL20_TROWT
Sequence: MVRVARSVNARKKRRSILAAAKGYRGQRSRLYRKAKEQVLRSLVYAYRDRRKRKSNFRKLWIIRINAAARMEGVTYNRFLQGLKLANIELDRRSLAHLAVHNPDTFSALVGVAKDSLKNAPDPVAAARLRGTSSRT
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: PCP_ALIFM
Sequence: MKKILITGFEPFGNDKINPALEAVKLIAGRKLNGGEIVICQVPVVRYKSIETVKQAIEEQQPYAVITVGQASGRAAITPERIAINVDDFRIPDNEGIQVIDEPVVAGGPDAYFTTLPIKAMVSEIQAQGIPATVSNTAGTFVCNHLFYGIQHYLKDTNVRHGFVHIPLLPEQSVDGSQPTMKLEQIAEGLAIAAQAIIDNDSDIQQGAGTIC
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_MARN8
Sequence: MARVKRGVVARRRHKKILNQAKGYYGARSRVYRVAKQAVIKAGQYAYRDRRNRKRAFRALWIARINAGARANGLSYSRLIAGLKKANVEIDRKVLADLAMNEQQAFAAVVEKAKASL
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RRF_STAA1
Sequence: MSDIINETKSRMQKSIESLSRELANISAGRANSNLLNGVTVDYYGAPTPVQQLASINVPEARLLVISPYDKTSVADIEKAIIAANLGVNPTSDGEVIRIAVPALTEERRKERVKDVKKIGEEAKVSVRNIRRDMNDQLKKDEKNGDITEDELRSGTEDVQKATDNSIKEIDQMIADKEKDIMSV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAFA2_MOUSE
Sequence: MGAGQSVCFPPISGPHHIGCTDVMEGHSLEGSLFRLFYPCQASEKCEQPLWIPRYEYSMGLADYLQYNKRWVGLLFNVGIGSCRLPVSWNGPFKAKESGYPLIILSHGLGGFRASYSAFCMELASRGFVVAAVEHRDQSAAATYFCKPTSQESSPAESLEEEWLPFRRIKEGEKEFHVRNPQVHQRVKECVRVLRILQDASAGKTVVNVFPGGLDLMTLKGSIDRNRVAVMGHSFGGATAVLALTQEVQFRCAIALDAWMFPLERDFYPKARGPVFFINVEKFQTVESVNLMKKICAQHEQSRIVTVLGAVHRSQTDFAFVTGNLIAKFFSSNSRGTLDPYESQEVMVRAILAFLQKHLDLKEDYDQWSSFIEGVGPSLIQGAPHYLSSL
What is the function of this protein?
Catalyzes the hydrolyze of the acetyl group at the sn-2 position of platelet-activating factor (PAF) and its analogs, leading to their inactivation (By similarity).  Hydrolyzes propionyl and butyroyl moieties approximately half as effectively as PAF (By similarity).  Also catalyzes transacetylation of the acetyl group from platelet-activating factor (PAF) to lysoplasmalogen and to sphingosine, producing plasmalogen analogs of PAF and N-acetylsphingosine (C2-ceramide) respectively.  Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position (By similarity).
What are the official names of this protein?
Platelet-activating factor acetylhydrolase 2, cytoplasmic, PAF:lysophospholipid transacetylase, PAF:sphingosine transacetylase, Platelet-activating factor acetyltransferase PAFAH2, Serine-dependent phospholipase A2, SD-PLA2.
What is the protein family that this protein belongs to?
Belongs to the serine esterase family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Lipid-anchor. Endoplasmic reticulum membrane; Lipid-anchor. Note=In resting cells, localizes to intracellular membranes and cytoplasm. Translocates from the cytoplasm to intracellular membranes upon oxidative stress.
Protein: VM23B_ECHCA
Sequence: NSVHPCCDPVKCEPREGEHCISGPCCRNCKFLNAGTICKRAMLDGLNDYCTGISTDCPRNRYKGKED
What is the function of this protein?
Inhibits adhesion of cells expressing alpha-4/beta-1 (ITGA4/ITGB1) and alpha-4/beta-7 (ITGA4/ITGB7) integrins to the natural ligands vascular cell adhesion molecule 1 (VCAM-1) and mucosal addressin cell adhesion molecule 1 (MADCAM-1).  It is also a weaker inhibitor of alpha-5/beta-1 (ITGA5/ITGB1) and alpha-2b/beta-3 (ITGA2B/ITGB3) integrins.  The inhibitory activity of EC3 towards alpha-4 integrins is associated with the MLD sequence of EC3B subunit.  The ability of EC3 to inhibit ITGA5/ITGB1 resides in both subunits A and B.
What are the official names of this protein?
Disintegrin EC3B.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIe sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOH_METPP
Sequence: MIESFNQFGSSLLGGFWPVVWNLIKIVALIAPLMGCVAYLTLWERKAIGWTQIRPGPNRVGPWGLLTPIADAVKLIFKEIILPTAANKGLFLLGPVMTIMPALAAWVVVPFGPEVALANINAGLLFLMAITSMEVYGVIIAGWASNSKYAFLGALRASAQMVSYEIAMGFALVVVLMVSGTLNMTEIVLGQDRGRFADMGLNFLSWNWLPLFPIFIVYFISGLAETNRHPFDVVEGESEIVAGHMIEYSGMAFAMFFLAEYANMILISALAVTMFLGGWLPPIDSVVFNWIPGWIWLGLKTFVVVTMFLWVRSTFPRFRYDQIMRLGWKIFIPITLIWLVVVGLWIQSPWNIWK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.