PharMolix/UniProtQA huggingface dataset:
Protein: THI4_YEAST
Sequence: MSATSTATSTSASQLHLNSTPVTHCLSDIVKKEDWSDFKFAPIRESTVSRAMTSRYFKDLDKFAVSDVIIVGAGSSGLSAAYVIAKNRPDLKVCIIESSVAPGGGSWLGGQLFSAMVMRKPAHLFLQELEIPYEDEGDYVVVKHAALFISTVLSKVLQLPNVKLFNATCVEDLVTRPPTEKGEVTVAGVVTNWTLVTQAHGTQCCMDPNVIELAGYKNDGTRDLSQKHGVILSTTGHDGPFGAFCAKRIVDIDQNQKLGGMKGLDMNHAEHDVVIHSGAYAGVDNMYFAGMEVAELDGLNRMGPTFGAMALSGVHAAEQILKHFAA
What is the function of this protein?
Involved in biosynthesis of the thiamine precursor thiazole.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate.  The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate.  The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.  May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
What are the official names of this protein?
Thiamine thiazole synthase, Thiazole biosynthetic enzyme.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Excluded from the vacuole.
Protein: DPOL_WHV5
Sequence: MHPFSRLFRNIQSLGEEEVQELLGPPEDALPLLAGEDLNHRVADALNLHLPTADLQWVHKTNAITGLYSNQAAQFNPNWIQPEFPELHLHNDLIQKLQQYFGPLTINEKRKLQLNFPARFFPKATKYFPLIKGIKNNYPNFALEHFFATANYLWTLWEAGILYLRKNQTTLTFKGKPYSWEHRQLVQHNGQQHKSHLQSRQNSSMVACSGHLLHNHLSSESVSVSTRNLSNNISDKSQKSTRTGLCSYKQIQTDRLEHLARISCGSKIFIGQQGSSPKTLYKSISSNFRNQTWAYNSSRNSGHTTWFSSASNSNKSRSREKAYSSNSTSKRYSPPLNYEKSDFSSPGVRRRITRLDNNGTPTQCLWRSFYNTKPCGSYCIHHIVSSLDDWGPCTVTGDVTIKSPRTPRRITGGVFLVDKNPNNSSESRLVVDFSQFSRGHTRVHWPKFAVPNLQTLANLLSTNLQWLSLDVSAAFYHIPISPAAVPHLLVGSPGLERFYTCLSSSTHNRNNSQLQTMHNLCTRHVYSSLLLLFKTYGRKLHLLAHPFIMGFRKLPMGVGLSPFLLAQFTSALASMVRRNFPHCVVFAYMDDLVLGARTSEHLTAIYSHICSVFLDLGIHLNVNKTKWWGNHLHFMGYVITSSGVLPQDKHVKKISRYLHSVPVNQPLDYKICERLTGILNYVAPFTLCGYAALMPLYHAIASRMAFIFSSLYKSWLLSLYEELWPVVRQRGVVCTVFADATPTGWGIATTCQLLSGTFAFPLPIATAELIAACLARCWTGARLLGTDNSVVLSGKLTSFPWLLACVAHWILRGTSFCYVPSALNPADLPSRGLLPALRPLPRLRLRPQTSRISLWAASPPVSPRRPVRVAWSSPVQTCEPWIPP
What is the function of this protein?
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid.  Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA).  The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
What are the official names of this protein?
Protein P.
What is the protein family that this protein belongs to?
Belongs to the hepadnaviridae P protein family.
Protein: MRG1_CAEEL
Sequence: MSSKKNFEVGENVACIYKGKPYDAKITDIKTNSDGKELYCVHFKGWNNRYDEKIPVGEEKDRIFKGTASEYAEKHNAELPTTALKPKKKSLAAEAPRDDRDDTPGTSKGKKAKSVTIAPVMTADDMKVELPKPLRKILIDDYDLVCRYFINIVPHEYSVDQIIEDYIKTIPVSNEQMRTVDDLLIEYEEADIKITNLALICTARGLVDYFNVTLGSSYQLLYKFERPQYNDLVKKRAMEKGIDITNPTALQDSGFRPSQEYGIVHFLRMLAKLPDYLKLTQWNDHVINRIMIGVHDLIVFLNKNHGKYYRGSSDYQGASNDYYRRSLAADDGVGANQ
What is the function of this protein?
Protein involved in the remodeling of chromatin thereby regulating various processes including transcription, chromosome synapsis and genome integrity (PubMed:22172672, PubMed:22212480, PubMed:17215300, PubMed:30929290).  Mainly binds genomic loci carrying trimethylated histone H3 'Lys-36' (H3K36me3) or 'Lys-4' (H3K4me3), and acetylated histone H3 'Lys-9' (H3K9ac), 'Lys-27' (H3K27ac) (PubMed:30425042, PubMed:31118512).  During meiosis, required for the presynaptic pairing of homologous chromosomal regions outside of the pairing center and for the progression of chromosome synapsis (PubMed:22172672, PubMed:22212480).  Essential maternal factor required in postembryonic germline development and in maintaining germ cell identity (PubMed:12175490, PubMed:30425042).  Plays an important role in maintaining genomic integrity in primordial germ cells (PGCs) during meiosis by regulating DNA double-strand break (DSB) repair and synapsis (PubMed:22212480, PubMed:30929290).  Also, required for chromatin-based transcriptional silencing in PGCs and for silencing of X-linked genes in the maternal germ line (PubMed:17215300, PubMed:30929290).  By retaining histone acetyltransferase, cbp-1, in euchromatin, promotes the anchoring of heterochromatin at the inner nuclear membrane in intestinal and hypodermal cells (PubMed:31118512).
What are the official names of this protein?
Mortality factor related protein 1.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Concentrated on euchromatic regions marked by H3K36me2/me3 and probably enriched on autosomes.
Protein: POLR_EPMV
Sequence: MAFQSALEALNSTTHRDASTNPILNSVVEPLRDSLSLYPWLLPKEAVPHLLSWGIPNSGLGVTPHPHPIHKTVETFLLFNHWHALARLPSTVMFMKPSKFQKLAALNPKFQELINFRLTAADTTRYPSTSLTFPSNSICFMHDALMYFSPAQIVDLFTQSPALETLYCSLIVPPESHFTDLSLFPEIYTYKISGQTLHYIPENHHSGSYNQPLQAPSWLKISSILSPSLALSVTKLESWGPVHSILIQRGLPPKPSLSARPPVLPNQPPRATTPNSQNQLLHQTSQLFFQLQQPQLSLVSFRIPDCVELPQATFLRQPLRHRLVPTSVYNALFTYTRAVRTLRTSDPAGFVRTQSNKPEHAWVTPNAWDNLQTLSVNAPHRPQVCYHFFSSPVARLKLHFAQHWRAYLLALTPFLTTSPLLLPLFNFNTPFPLPRLLSLFRRSVSSPRLLHSILPSQLRGAAIPNRPLPLWVTKLHHFLDSHSLLPTPPIRPRIELQRLPLMSLIPKPKIVLPLLSLLLSSPTIYIHFFQAQTPQQLHDNYHLHLHPSRFELSWTLQSYHVTQAQSFLPLLLPAPTQAQASNPAPRPPAFHAIPLPPQPSTSSSPPLQEPTLSPHLIHPPLTREPSPLNGCACDSALLPSTAAMTSAEHPTPLNPPTPSPTPDVPPPDSPGNPSLLKQVPPEANLHPIHNPDLPSSTTLPSGALTLVPAKTPSIYANPTPPSSHPFTPLADDPTAVGPCLPFHVLHPADYFPLSAEFLTRTRHVPPSSLSHPKLNCLLTCFSELSGHSESDLWLSLQSILPDSQLQNPEVSTLGLSTDILTALCFIYHSSVTLHAPSGVYHYGIASSSTVYVIHYQPGPPPHFSLSPRLAASAPRCNPTNSRLVRQALRFKLNGEFLPFTQAYAHESSITHAKNLISNMKNGFDGIMSSLTDSSKGPSPREKLTTLDSLIDVAAPREVSLIHIAGFAGCGKTHPIQKLLQTSPFHDFRISCPTNELRSEWKRDMQPTAENVWRFSTWESSLLKHSEILVIDEIYKLPRGYLDLSILADPTLSLVIILGDPLQGEYHSTSPHSSNHFLPSEVHRFKSYIDCYCFWSHRIPKQIASLFGVVCHNTNEGFVRALTSHPPNSKNLTNATNTALSLQQMGHHAITISARRVTFTEAHTILLDRHTNLLSPNNCLVALTRSRTGVYFVGNLHLASNSFGTNYMFSQALCQGTIDLNNVFPHIMPHLPKMYEPIRSRSNRFVSGSLNFRPTTNSRLLSSLTKPTHLPPHIPTNHSLDVLVSNPVLLGETLDPRLEVLHLPPTRLPLHLDLLPTVPSSSSFSSVDHLFPTPISPAICGYTFENLAAFFLPAHDPDLKEVLINDQKSNQFPYLDAPFELSCQPSSLLAPIHKPASDPTLLPGSIKKRLRFRASSSPYSITPSDQLLGQHLFSSLCLAYGRNPNSVLPFQPELFSECICINDYAQLSSKTQATIVANHQRSDPDWRLTAVRIFAKAQHKVNDASIFSGWKACQTLALMHGYIILVLGPVKKYQRIFDSKDRPPHIYYHCGKTPSQLSQWCQTHLSGSSYIANDYTAFDQSQHGEAVVLECLKMRRLSIPDSLIQLHSHLKCSVDTQFGPLTCMRLTGEPGTYDDNSDYNLAVIYSQYSLNGHPILISGDDSVLCGTPPPSPLWPTLKKMLHLRFKIERTSHPLFCGYYVSPHGAARNPYALFAKLMICVDDKSLHDKKLSYLSEFSTGHLAGDLVTSILPSHLLPYQSAVHDFFCRNCTPAEKILLSLDPIPESKILQLILKVRWASQAFFSYLPQKARELLVARSSLPSLYSNPKVSQLESELLPFSQ
What are the official names of this protein?
RNA replicase polyprotein.
What is the protein family that this protein belongs to?
Belongs to the tymovirus NS35 RNA replicase polyprotein family.
Protein: PTH_DESVM
Sequence: MNVAGLIVGLGNPGKEYERTRHNLGFMAVDALMEAAARETGGGCDQLSGGKKKYDLWRCRITPTGDPWLVAKPQTFMNLSGEAVLAIASYYRIKPDAILVVHDELDIPLGRMKFKTGGGNAGHNGLKSITQLLGTPDFHRLRLGIGRSPHGGETTNWVLGRLSGPEQTLLDTLLPAAVQAMTIFASQGAAAATQFANAYKPD
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_WOLSU
Sequence: MVTMKDLLECGVHFGHQTRRWNPKMKKYIFGVRKNIHIIDLQKTLRYFRYTYNVVRDAAAEGKTVMFVGTKKQASETIKQYADTINAPYVNYRWLGGMLTNFSTIKKSIRKLEVIEEMEASGQIELLTKKEKLMLTRKKEKLEKYLGGVRHMKKAPDMLFVVDAAKEKIAVAEARRLGIPVVAPLDTNCDPDVVDFPIPGNDDAIRSIQLFCKEMAEAIQEGRALAGSEEGEATEEVTPASEAEKQEVLAEAMSEEGDALQESEVVEEEEK
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: NNRE_CAEEL
Sequence: MVHIISKKTVSFIGQKLAAQIDEQLFTKYGFKVEQLMELAGLAAAQAIAAHYPKSNVAVLCGPGNNGGDGFVCARHLQQFGFTPSIVYPKESRNELMKSLVVQCETSSIPITATLPTNLQAFPLIVDALFGFSFHPPTREPFTEMLKTVRASGIHVFSIDVPSGWDVELGAPSGNDDDVIHPHSVISLTLPKLCMKNWTGPHFLGGRFVPKSLVDEHELLMPQYPGFEQIVKLED
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
Protein: METE_AERS4
Sequence: MTRAHTLGFPRIGAKRELKFALESYWRGETTQAELIATGKSLRERHWQAQRTAGVNLLPVGDFAWYDQVLGTSLLVDAVPARHRHGDTDLDTLFRVARGRAPTGPSAAAAEMTKWFNTNYHYLVPEFSRDQRFKLGWSQLFDEVEEAKALGLPVKAVLLGPVSYLWLGKEKESGFSRLELLDRLLIVYQEILAKLAAQGVEWVQIDEPALALDLPDEWRLAYLNAYERLSGPCKLLLTTYFGSVAHQRDIITSLKVDGLHLDLVAAPEQLETLVPHLPAQWVLSAGVINGRNVWRANLAKLAPTLKALKEKLGERLWVASSCSLLHSPVDLTLEHELDPQTRSWFAFALQKCYELGLLSDYLDGGDLDKITAYSQPLVDRESDSRVHKKAVQSRLASLTNSDFDRQSAYPVRAQAQRNDLKLPLLPTTTIGSFPQTSEIRVLRQEWRAGRIDDSAYEAGIQAQIKDAIERQEAIGLDVLVHGEAERNDMVEYFGELLDGFAITRFGWVQSYGSRCVKPPVITTDIDRPTPMTLEWTKFAQSLTDKPVKGMLTGPVTILCWSFPREDVSREQSALQIGLAIRDEVADLEAAGIKIIQIDEPAIREGLPLRKQDHQAYLDWAVRAFRLSASPVVDSTQIHTHMCYSDFNLIIEAVAALDADVITIETSRSQMQLLEAFERFNYPNEIGPGVYDIHSPNVPSQGWIEDLIRKAAKQIPADRLWVNPDCGLKTRGWEETEAALKVMVNATKALRTELA
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: ZN706_MOUSE
Sequence: MARGQQKIQSQQKNAKKQAGQKKKQGHDQKAAAKAALIYTCTVCRTQMPDPKTFKQHFESKHPKTPLPPELADVQA
What is the function of this protein?
Transcription repressor involved in the exit of embryonic stem cells (ESCs) from self-renewal.  Acts by repressing expression of KLF4.
What are the official names of this protein?
Zinc finger protein 706.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS16_VIBPA
Sequence: MVTIRLARHGAKKRPFYQIVVADSRNAATGRFIEKVGFFNPTAKGQEEGLRLDLDRVNHWVGQGASVSDRVAKLVKDAQKAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: Y2324_MYCBO
Sequence: MHAKVGDYLVVKGTTTERHDQHAEIIEVRSADGSPPYVVRWLVNGHETTVYPGSDAVVVTATEHAEAEKRAAARAGHAAT
What are the official names of this protein?
Uncharacterized protein Mb2324.
What is the protein family that this protein belongs to?
To M.leprae U650M.
Protein: CWP09_PHAVU
Sequence: NSKPPEALILVKXSQ
What are the official names of this protein?
45 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: HSPB7_MOUSE
Sequence: MSHRTSSAFRAERSFRSSSSSSSSSSSSASRALPAQDPPMEKALSMFSDDFGSFMLPHSEPLAFPARPGGQGNIKTLGDAYEFTVDMRDFSPEDIIVTTFNNHIEVRAEKLAADGTVMNTFAHKCQLPEDVDPTSVTSALREDGSLTIRARRHPHTEHVQQTFRTEIKI
What are the official names of this protein?
Heat shock protein beta-7, HspB7, Cardiovascular heat shock protein, cvHsp, Heat shock protein 25 kDa 2, Protein p19/6.8.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, Cajal body. Note=Resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Protein: CSP_PLAVS
Sequence: MKNFILLAVSSILLVDLFPTHCGHNVDLSKAINLNGVNFNNVDASSLGAAHVGQSASRGRGLGENPDDEEGDAKKKKDGKKAEPKNPRENKLKQPGDRADGQPAGDRADGQPAGDRADGQPAGDRADGQPAGDRAAGQPAGDRADGQPAGDRADGQPAGDRADGQPAGDRADGQPAGDRAAGQPAGDRAAGQPAGDRADGQPAGDRAAGQPAGDRADGQPAGDRAAGQPAGDRADGQPAGDRAAGQPAGDRAAGQPAGDRAAGQAAGDRAAGQAAGGNAGGQGQNNEGANAPNEKSVKEYLDKVRATVGTEWTPCSVTCGVGVRVRRRVNAANKKPEDLTLNDLETDVCTMDKCAGIFNVVSNSLGLVILLVLALFN
What is the function of this protein?
In the vertebrate host, binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes and is required for sporozoite invasion of the host hepatocytes.
What are the official names of this protein?
Circumsporozoite protein, CS.
What is the protein family that this protein belongs to?
Belongs to the plasmodium circumsporozoite protein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Cytoplasm. Note=Localizes to the cytoplasm and the cell membrane in oocysts at day 6 post infection and then gradually distributes over the entire cell surface of the sporoblast and the budding sporozoites.
Protein: RS17_MYCGE
Sequence: MKRNQRKQLIGTVVSTKNAKTATVKVTSRFKHPLYHKSVIRHKKYHVHNFGELVANDGDRVQIIETRPLSALKRWRIVKIIERAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: Y1737_BURA4
Sequence: MLKGNLAGLMKQAQQMQENMKKMQEQLAQIEVEGQSGAGLVKVTMTCRNEVRRVAIDPSLLADDKDMLEDLVAAAFNDAVRKAEATSQEKMSGMTSGLPLPPGFKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein BamMC406_1737.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ATPE_PIPCE
Sequence: MTLNLCVLTPNRIIWDSEVKEIILPTNSGQIGVLPNHAPIATAVDIGILRIRLDDQWVTMALMGGFARIGNNEITILVNDAERGSDIDLQEAQGTLEIAEANLNKAEGKRQVIEANLALRRARTRVEAVNTIS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: IF1C_NANDO
Sequence: MKEQKWIHEGLITESLPNGMFRVRLDNEDLILGYVSGRIRRSFIRILPGDRVKIEVSRYDSTRGRIIYRLRNKDSND
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: VPC19_MYCTO
Sequence: MKLIDTTIAVDHLRGEPAAAVLLAELINNGEEIAASELVRFELLAGVRESELAALEAFFSAVVWTLVTEDIARIGGRLARRYRSSHRGIDDVDYLIAATAIVVDADLLTTNVRHFPMFPDLQPPY
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.  Its toxic effect is neutralized by coexpression with cognate antitoxin VapB19 (By similarity).
What are the official names of this protein?
Ribonuclease VapC19, RNase VapC19, Toxin VapC19.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: MCSB_GEOKA
Sequence: MSFEKFFNTAVSAWMSQEGPDSDIVLSSRIRLARNIVDFRFPTLFSSEEAMQIVALFERTFAHRSYGGAGRFELLKMSELQPIEKRVLVEKHLISPHLAEDSPFGACLLSENEEISIMINEEDHIRIQCLFPGLQLAEALEAASELDDWIEGYVNYAFDERLGYLTSCPTNVGTGLRASVMMHLPALVLTQQINRIIPAINQLGLVVRGTYGEGSEALGNIFQISNQITLGKSEEDIVADLHTIVQQLIAQERAARQALVKTLGIQLEDKVFRSYGILANCRVIESKEAAQCLSDVRLGIDLGYIKNISRNILNELMILTQPGFLQQYAGGALRPEERDVRRAALIRERLKMEERRKMEGDER
What is the function of this protein?
Catalyzes the specific phosphorylation of arginine residues in a large number of proteins.  Is part of the bacterial stress response system.  Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity.
What are the official names of this protein?
Protein-arginine kinase.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: RL29_FRAT1
Sequence: MKRKDTLKDYRGKSIDQLQEAKIELLQQLFSLRMQKGTGQLKKNHLFKSAKRDIARINTIISEKNK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RGPS2_HUMAN
Sequence: MDLMNGQASSVNIAATASEKSSSSESLSDKGSELKKSFDAVVFDVLKVTPEEYAGQITLMDVPVFKAIQPDELSSCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKTTFEKLEYVMSKEDNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILENEQRSNLMNNILRIISDLQQSCEYDIPMLPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEPGTSTPRSAASREDLVGPEVGASPQSGRKSVAAEGALLPQTPPSPRNLIPHGHRKCHSLGYNFIHKMNTAEFKSATFPNAGPRHLLDDSVMEPHAPSRGQAESSTLSSGISIGSSDGSELSEETSWPAFERNRLYHSLGPVTRVARNGYRSHMKASSSAESEDLAVHLYPGAVTIQGVLRRKTLLKEGKKPTVASWTKYWAALCGTQLFYYAAKSLKATERKHFKSTSNKNVSVIGWMVMMADDPEHPDLFLLTDSEKGNSYKFQAGNRMNAMLWFKHLSAACQSNKQQVPTNLMTFE
What is the function of this protein?
Guanine nucleotide exchange factor for the small GTPase RALA.  May be involved in cytoskeletal organization.  May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity).
What are the official names of this protein?
Ras-specific guanine nucleotide-releasing factor RalGPS2, Ral GEF with PH domain and SH3-binding motif 2, RalA exchange factor RalGPS2.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Associates with membranes through the PH domain.
Protein: SYAM_CAEEL
Sequence: MGIGSKILENNIQKSISLGFYHSHSELRKSFYEFFKSKNHEILRSSSVIPDENDGTLLFTNAGMNQFKPLILSSTESRRVANIQKCIRAGGKHNDLDDVGKDLHHQTFFEMMGNWSFNDAFSKEEACRYAWEYLVEILGINADRLYVSYFGGIEKLGLPEDRECREIWKRIGVSSNRILPFVAENFWEMGAAGPCGPCTEIHYDRIGGRDASRLVNIDDSVVEIWNIVFMSSVRDSCGQIRHLGKNHIDTGMGFERLLSVVQNKTSNFDTDVFTPILEKTSELAKKQYTGSLDSRQDATFRLVADHIRAATVAISDGAVPDGTGCGFIVRKMMRRAFLQGISKLGIERYAMSELVPVVASTMKEVYPEIHDTSTHIRKIFNDEEAQFWKTVDKAKKMFDSVAAESKSPIISGRKAFNLFETHGLPLAVTVELARNIGREVDETEFERCRLEAQKVSQKASQFKLPISADDFPSHSDKEKYSYVFRNGKYEFPQVKTRILQVYKDQQKAESLEANDRGFLVLEECQFYGEQGGQTSDTGHLLIDGREVFEVENAKKIAGGAVTVLFGRALLPIRRDLRVEQKLDETRREGVMRAHSATHLLNWALQKLGVGSGQKGSSVDCDRFRFDYSTGDEDLSKEQRTELLIKCEMKMREFIQNGGFTEIIETSLEEAKKIENLQSDVKEDRIGGASVRVVALGSGADVPVECCSGTHIHDVRVIDDVAIMSDKSMGQRLRRIIVLTGKEAAACRNYTKSIYEDLRSTDPKERSKTGKNIDWKRVPIADQARISILLKQKK
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, mitochondrial, AlaRS B, Alanyl-tRNA synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CYSH_PSEAE
Sequence: MLPFATIPATERNSAAQHQDPSPMSQPFDLPALASSLADKSPQDILKAAFEHFGDELWISFSGAEDVVLVDMAWKLNRNVKVFSLDTGRLHPETYRFIDQVREHYGIAIDVLSPDPRLLEPLVKEKGLFSFYRDGHGECCGIRKIEPLKRKLAGVRAWATGQRRDQSPGTRSQVAVLEIDGAFSTPEKPLYKFNPLSSMTSEEVWGYIRMLELPYNSLHERGYISIGCEPCTRPVLPNQHEREGRWWWEEATHKECGLHAGNLISKA
What is the function of this protein?
Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
What are the official names of this protein?
Adenosine 5'-phosphosulfate reductase, APS reductase, 5'-adenylylsulfate reductase, Thioredoxin-dependent 5'-adenylylsulfate reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDRP_RBDVR
Sequence: MECLDFSKLWFSTAAGLQQRCYYDCVAWECLGDDDLQIFISGLNRLIESVAVSCTGDEDLDFVVDSCNEFVTGRDLKSFFAADLPVREVSSVGCISHFIPGSVSGLNVSDLLDNQLYGCSVFSSDFESKLRDIRDAALSDAASGVSQLVSCHFEKDVRHLLAENANSVKIPVPQKLSDDDMRILRDHFPRYELKFTQNVDGPHNMAAAHRLLETHDLLSNFPADAPILDIGGNWFSHFRYGRSNVHSCCPMLDLRDNERHTHRLTMTESLMSSLRHRYAGTIDLDPDAHLSRKVSDSMKEFYKRWAVHPKDLIRLYAGIRDGNSSLYCHHKFGVSWNDVLWESERNNCLTVPEPECPFKAKYAIMVHSGYDLPLKELIGGMVQHGVVELHGTMIADPAMLVATSGYIPALRCNWEKSKGQIWFSFRDDSTMGYRHDWEVYSKYLTSTVVSCGKHFYVMERDKYRHGVLFYSIIKCSGSLRKGDHTFFHNAWFHEMYDKYIMKVPLVKVKDLTGDEGSVECSWREVVMSRKLVDRVIEVCLRGVKPINFGNCDDAVHMDNLRIIQNHLLSHSQTLVLNGSTIIREEAIPFKDFSPVSVTIYFEILLTRYKESLSLAWFHAGLGPDFKLGSWVSSLKRVFYRILGFPANLLKYVLNALFRCRDKVSDMEFVKPAVEKLTVLENTYIGKSLMGDCPTLKEYDDSAFFNILENVGNELFNNSSTDSGKPETPEVTMTGNPNAVIAEAISYCRAEVDRIGKKCERILHAYQATGNCGGYLNDTDNVGVFDKMTSWVQKPKEFDHEFGWDGSSFIKLSWFGKIPDFVGRYLVVTDGTRVTTNLKFSRQYATIPATVTPTIKLVDGVTGCGKTTEIVRRYRPGILILSVCKANVDEIRRKLAAVDSKFIRTVDSYLLSPSVTGSCDELFIDEYGLSHPGILLLAIHISGIRKVTLFGDSEQIPFCNRLADFPLKYNSVEDVGLNFDREIRSTTYRCPQDITLSLQKMYKTKPIKTVSTVESSITIKPIKSEFEIPLPNAFDGPVLYICMTKHDESLLKLRWAKENISSEVRTVHAAQGLSYKNVVYFRLTRTDNDLYTKRKLPYHLVAISRHTDKIVYCTTKPEDSSDFSLSALKNTIKTSRDLTQEASGSESSYAVVFESNSEVTATKPEVCENVRKAAEMNFPVSSDALYQKEVPIYGAIPDPKGKASYNPGSVIRAIEELTPGNTSIDTDALDELVEVGPMSLQVGSIRWDVSKISPRLFTNNKFAVPHLPTGALLRRNTSSRQVGLAIEKRNANVMNSQKYFDLENLANKAVERFFDFFIDMEKFSKLPTGVLGSSAEQIQTYQNKTGNKVTDPVCVALSPIQKYKHMIKRDVKFNLTDGAQSEYTKAATITYHQPEITQVATAIFGQFKTRLLACRNKFLNIPLEHDNDLSGYLTKYHLGSENNTFTEIDFSKFDKSQGEIHQLIQDLILIKFGCDPEFVALWSTAHRSSSIFDQNVGIGFKTDFQRRTGDAFTFLGNSLVTAAMLAFVISDPDREKIRYMLVGGDDSLICSYGPIQVPLEPLGDIFNMSCKLVQPACPYFASRYLIRRGDEILCVPDPYKLLVKLGRKDVPDNQASLCEIRTGLADSAKYIFDDIVKQKLAILVQVRYNKAAPSLYDALCTVHWALSSNTNFSKFYTVTNTSNEVRRNRRGVKIT
What is the function of this protein?
RNA-dependent RNA polymerase replicates the viral genome.
What are the official names of this protein?
Methyltransferase/helicase/RNA-directed RNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the ssRNA positive-strand viruses RNA-directed RNA polymerase family.
Protein: PFDB_CALMQ
Sequence: MATEIPPAVRNDLDRLRQLEDQLQAVLLRKQQYEGELRNVDKALNELNKLPQDSKVYKVVGTFLLSTTRDEAIQDLNQRKELLDLHLQSLVKQENMLRKQISELENKVKQVLAAGQGGQVQ
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit beta, GimC subunit beta.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
What are the subcellular locations of this protein?
Cytoplasm.