PharMolix/UniProtQA huggingface dataset:
Protein: TRMD_PERMH
Sequence: MKFFVLTIFPQFFEGFINTGIVSRAVKKGIVDIKSVDLRDFTEDKHRTVDDVVYGGGPGMLLKPEPIFKAYDSITEKGHKPYVLITEPWGRKFDQKFAEELSKKEEIMIICGRYEGVDERVKSIVDEEVSIGDFILSGGEPAALVIMDAVIRLIPGVVGDSESLNADSFSNDGLLGYPNYTRPAEYRGMKVPEVLRSGNHKLIKLWRRWKQIEKTAVRKPELLKKADLSDSDKKIIDAIKKGLSFEDFLKKYKV
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SP77B_DROME
Sequence: MGKIADCLMLWIPLLLGAIFLCSADPQNNQAPLQLSVGNPLTAFTAPTAFQSGVSHIQSMRSNFDTDVLVSISQGVQDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRINVEDEKLRGAYKVWSSFLNITTSTIEVATLQAIYTGKGYPIKNNYRDAIQNYNVQPMEVDFYSPDSVIQINEDTNRTTRGLIPYTILPQDVYGAKMFLLSSLYFKGQWKFPFNKTLTREEPFFSESGEVIGKIPMMVQEANFAYVSNVEGLDGYVLELPYGTQDRLAMIVVLPKRGFKLNDVANNLKALGLRPILQRLAAFRNRASEDNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTANLDRMSSGLFAKLVVHSTKIIVDEQGTTAGAVTEAALANKATPPKFLLNRPFQYMIVEKATGLLLFAGQVRNPKAA
What is the function of this protein?
Serine protease inhibitor which plays an essential role in regulating the tracheal melanization immune response to bacterial and fungal infection (PubMed:18854145, PubMed:22227521).  Acts by negatively regulating a protease cascade involving Mp1 and Sp7, that functions in the activation of the Hayan-phenoloxidase (PPO1) cascade (PubMed:18854145).
What are the official names of this protein?
Serine protease inhibitor 77Ba, Serpin 77Ba.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted, extracellular space. Note=Detected in the extracellular space at the apical surface of tracheal cells.
Protein: PYRH_THEM4
Sequence: MYKRVLLKLSGEVLSGEGEKGFNHENIIYLVDELKKILEYGTNVGIVIGAGNLFRGREMQELSPTIADQIGMLGTVINALYLKDIFEKNNLRTVVVSQVSSLPSIRPIHYDDINLYFDAGYLVIFAGGTSNPFFTTDTAAALRAVEMKADILIKGTKVDGIYDKDPKKFTDARKFDTLTYDEAIDKGLKIMDTEAFSICKRYDMKILVMDFFKESNLLSAVREENVGTLVVPK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_PSYWF
Sequence: MKRTFQPSVIKRKRTHGFRARMATKKGRQVLARRRAKGRHRLTV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: TNFC_PIG
Sequence: AWITGQGLGWEAKKEEAFLRSGTQFSGAEGLALPQDGLYYLYCHVGYRGRAPPPGGDPLDRSVTLLSRLYRAGGAYGPGTPELLLEGAETVTPVLDPSRRHEYGPLWYTSVGFGGLVQLRRGERVYVNISHPDMVDYRRGKTFFGAVMVG
What is the function of this protein?
Cytokine that binds to LTBR/TNFRSF3.  May play a specific role in immune response regulation.  Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface.
What are the official names of this protein?
Lymphotoxin-beta, LT-beta, Tumor necrosis factor C, TNF-C, Tumor necrosis factor ligand superfamily member 3.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: RS11_STRPD
Sequence: MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSSAGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAGLEVTAIRDVTPVPHNGARPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: CT204_HUMAN
Sequence: MVPPKPALWALLLALLGTAPSRAYSPACSVPDVLRHYRAIIFEDLQAAVKWGGAGAEKTRPGSRHFHFIQKNLTRPGSSGRRGRPRASCGAQKEHSILLSISSLGRTLRGAVAGGRRGALERAAWTVAVRTEAVMRRHCRTLRQRSRRPKMRPARRRGGRRQLLLRALDAVATCWEKLFALRAPASRDS
What are the official names of this protein?
Uncharacterized protein C20orf204.
Protein: P4H2_ARATH
Sequence: MSMSRLGLLLFVAILLVLLQSSTCLISSPSSIINPSKVKQVSSKPRAFVYEGFLTDLECDHLISLAKENLQRSAVADNDNGESQVSDVRTSSGTFISKGKDPIVSGIEDKLSTWTFLPKENGEDLQVLRYEHGQKYDAHFDYFHDKVNIARGGHRIATVLLYLSNVTKGGETVFPDAQEFSRRSLSENKDDLSDCAKKGIAVKPKKGNALLFFNLQQDAIPDPFSLHGGCPVIEGEKWSATKWIHVDSFDKILTHDGNCTDVNESCERWAVLGECGKNPEYMVGTPEIPGNCRRSCKAC
What is the function of this protein?
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in proline-rich peptide sequences of plant glycoproteins and other proteins.  Hydroxyprolines are important constituent of many plant cell wall glycoproteins such as extensins, hydroxyproline-rich glycoproteins, lectins and arabinogalactan proteins.  Possesses high affinity for leucine-rich repeat and proline-rich extensins of root cell walls that are essential for root hair development.  Hydroxyprolines define the subsequent O-glycosylation sites by arabinosyltransferases which elongate the O-arabinosides on extensins.  Has low affinity for the substrates tested in vitro.
What are the official names of this protein?
Prolyl 4-hydroxylase 2, AtP4H-2, AtP4H2.
What is the protein family that this protein belongs to?
Belongs to the P4HA family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Note=Predominantly localized in the endoplasmic reticulum.
Protein: DNAE2_BORPA
Sequence: MSAILPGYAELHCQSNFSFLQGASHPEELVTRAGELGYAALALTDECSLAGVVRAHVEAREQKLPLIIGSSFTLQAGADAPPLDLTLLAQNREGYGNLAELITLGRGRAAKGQYLLTPADIEAPAGDNAHLRGMPDCLAILAPPPGLAAERLAEQARWLAAQCPGRAWIGLTLLHHCRDDLHRAAVEHAAHASGLPIVALGQAQMHRRSRKPLHDTLAAIRTGRSVGQCGYDLAANAERHLRSRLRLASLYPAQALAQTLAIARRCTFSLDELQYEYPDEIVPAGHTPASYLRQQTYLGARQRFPEGMTPAVAAQVEKELALINELRYEAYFLTVYDIVGYARSQGILCQGRGSAANSAVCYCLGITAVDPARGNTLFERFISKERNEPPDIDVDFEHQRREEVIQYIYEKYGRQRAALTAVVISYRPRSVLRDTGRALGVDNGIIDAVARAHQWWDGKKEMLRSLAACGLDPASRVARQWAELAETLMGFPRHLSQHPGGFVISRGKLSRLVPIENAAMPGRSVVQWDKDDLDALRLLKVDVLALGMLSVLRRALALAGQRRGRPLALHEIPPDDDATYDMICAADTIGVFQIESRAQMSMLPRLRPRQYYDLVVQVAIVRPGPIQGGMVPPYLRRRQGREDITYPGPAVRKALARTLGVPIFQEQVMQIAVDAAGFTPGEADALRRSMAAWRRKGGVDKFRAQLVGGLLARNYTADFAQALFRQIEGFGEYGFPESHAASFALLAYASSWLKCHEPEAFLAALLNSQPMGFYAPAQLVQDARRHGVRVLPADVLYSGWEASLQDAPGAARPAVRLGLNLVKGLREDSARAIEQARVRRPFADTADMARRAGLPRQALDALAAADALRTLAGHRRLASWQAAASAQSRDLLREAVIVETETPALPAPSEGQTVAADYRSVGLTLGRHPLALLRPQLAARNFQTAAVLNTYPNRRLARACGIVTVRQRPQTAKGTIFVTLEDETGPINAVVRPELIERQRRELLDATLLGIYGTWQSVDGVRHLVAQRLVDLSSLLGQLSQDGLAAASRNFH
What is the function of this protein?
DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS).  It is not the major replicative DNA polymerase.
What are the official names of this protein?
Error-prone DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDK8_DICDI
Sequence: MNTHNQSSNQNGGGSGGGGGGGGSSTFSPIVLTSTYRLDVQEKYTFSYEIGSGTYGMVYKADDKKRPNNKVAVKKFRSTKEGEGLSLTAYREIGLLKELSNENIVKLLDVCLNPKDKLLYLIFDYAEFDLFGIIKYHRENGSHFSDATIKSLIWQVLNGIHYLHSNWVIHRDLKPSNILVMGEGKECGTVKIGDFGLARIFQSPLKPLNENGVVVTIWYRSPELLLGSKHYTRAVDIWAIGCIFAELITTKPLFPGKEKDPKIPSLFQDDQVEKIIRVLGKPTLDMWPDIKHLPEWKRLSSMEAFPNSLAKCVGIDENSQAYDLLSKMILYDPSKRITASEALDHPYFKELPLPLPNAFSKPIPYPPRLPINKKKREFDD
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.  Phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex (By similarity).  Involved in cell aggregation, but not growth.  Required for starvation-induced expression of genes essential for early development of acaA and/or other genes.
What are the official names of this protein?
Probable cyclin-dependent kinase 8, Ddcdk8.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: O16B_CONPE
Sequence: MKLTCMMIVAVLFLTAWTVVTAEPHSSNVLENLYLKAHHEMENPEASKLNTRDDDCEPPGNFCGMIKIGPPCCSGWCFFACA
What is the function of this protein?
Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).  Acts on high voltage-activated (HVA) calcium currents in molluscan neurons.
What are the official names of this protein?
Omega-conotoxin PnVIB.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS7_HERA2
Sequence: MPRRRKIAKRIVPGDPIHNSIHVQMLINKVMMHGKKSVAENIVYRALDVAAQRLNREPVDLFEQVLRNSSPTIEVRPKRVGGSTYQVPVEVKSDRRIALAIRWLLTAARGRSGKPMHERLALELVDAFNNTGATVKRREEVHRMAEANRAFSHYARF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RS15_BAUCH
Sequence: MSLSFNTKAKIIADFGRNNYDSGSTAVQIALLTAQINHLQDHFAVHKKDHHSRRGLLRIVSQRRKLLVYFKNKDLASYTDLIERLNLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: Y454_HAEIN
Sequence: MFIVDSHCHLDALDYENLHKNISDVVEKAHARDVKHLLAIGVTLSRFEQAYDSLREFNNVSLACGVHPLDFEEEPYDAERLLRLAQDPKVIAIGEIGLDYYYSADNKAAQQAVFGSQIDIANQLDKPVIIHTRSAGDDTIAMLRQHRAEKCGGVIHCFTETMEFXKKALDLGFYISCSGIVTFKNAEAIREVIRYVPMERLLVETDSPYLAPVPYRGKENQPAYTREVCEYVATLKGVSAEAFAQITTQNFERLFKIRVE
What are the official names of this protein?
Uncharacterized metal-dependent hydrolase HI_0454.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.
Protein: RS20_MYCTU
Sequence: MANIKSQQKRNRTNERARLRNKAVKSSLRTAVRAFREAAHAGDKAKAAELLASTNRKLDKAASKGVIHKNQAANKKSALAQALNKL
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: LGT_ECO24
Sequence: MTSSYLHFPEFDPVIFSIGPVALHWYGLMYLVGFIFAMWLATRRANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPQFMADPLYLFRVWDGGMSFHGGLIGVIVVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPNFPFAMLFPGSRTEDILLLQTNPQWQSIFDTYGVLPRHPSQLYELLLEGVVLFIILNLYIRKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIVAGVIMMVWAYRRSPQQHVS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS3_STRS2
Sequence: MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRNFIKKELADASTSTIEIERAVNKVIVSIHTAKPGMVIGKAGSNVDALRAQLNKLTGKQVHINIIEIKQPDLDAHLVGESIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGADIARAEGYSEGTVPLHTLRADIDYAWEEALTTYGKLGVKVWIYRGEVLPARKNTKGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: NA13_ANTXA
Sequence: GAACFCDSDGPSVSGNTLSGILWLAGCPSGWHNCKAHGPNIGWCCKK
What is the function of this protein?
Binds specifically to voltage-gated sodium channels (Nav), thereby delaying their inactivation during signal transduction.  Thus it strongly stimulates mammalian cardiac muscle contraction.
What are the official names of this protein?
Delta-actitoxin-Axm1d, Delta-AITX-Axm1d, PCR2-1, Toxin PCR3.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type I subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: RSBZ3_ORYSJ
Sequence: MKKCPSELNFEAFFHGERGEDDADAAADQKPGGGPHPPPFAMFSAADLSSFGFADSVTSTITGVIPNHIWPQSQSLNARHPAVYTIESQSSICAAASPTSATTLNMKESQTLGGTSGSDSDSESLLDIEGGPCEQSTNPLDVKRMRRMVSNRESARRSRKRKQAHLADLETQVDQLRGENASLFKQLTDANQQFTTAVTDNRILKSDVEALRVKVKMAEDMVARGALSCGLGHLGGLSPALNPRQGACRVPDVLTGLDYAGDDPFTGLSPPEQVQMPGGGEVGDAWGWDNHSNGAMSK
What is the function of this protein?
Transcriptional activator that possesses broad binding specificity for DNA promoter elements with the core sequence 5'-ACGT-3'.  May be involved in the regulation of genes expressed during seed development (PubMed:7919992).  Binds to the DNA specific sequence 5'-TGAGTCA-3' found in seed storage protein gene promoters (PubMed:11133985).
What are the official names of this protein?
bZIP transcription factor RISBZ3, Rice seed bZIP3, bZIP transcription factor 20, OsbZIP20.
What are the subcellular locations of this protein?
Nucleus.
Protein: COBQ_BACFN
Sequence: MNKNLHPLMLAGTGSDVGKSIIAAAFCRIFLQDGYHPAPFKAQNMALNSYATPEGLEIGRAQAVQAEAAGVPCHTDMNPLLLKPSSDHTSQVVLNGRPIGNRNAYEYFRREGREELRKEVHAAFDRLAARYNPVVMEGAGSISEINLRDSDLVNLPMAMHAGADVILVADIDRGGVFASVYGSVMLLRPEERKHIKGILINKFRGDIRLFESGVKMLEDLCGVPVVGVVPYYKDIYIEEEDSVMLQTKNIRAGQGKVNVAVVLLRHLSNFTDFNVLERDPRVHLFYTNNTDELMKADIILLPGSKSTLSDLYELRRNGVAQAIVRAHREGATVMGICGGYQLMGREVCDPDHVEGEIERLPGLGLLPVSTRMQGEKVTRQVRFRFLEDSAVCEGYEIHMGTTTPLADVPVSPLNHLADGREDGYFVDRTCMGTYVHGILDNPSVIDYLLEPFADKLKETAFDYKAFKEEQYDKLAAHVRKHVDLPLIYQILTDND
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: RL32_STRMK
Sequence: MAVQKSRVTPSRRGQRRSHDALSAKQLSTDPTTGEVHLRHHITADGFYRGKKVIQTKTSAVEED
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: UL133_HCMVM
Sequence: MGCDVHDPSWQCQWGVPTIIVAWITCAALGIWCLAGSSADVSSGPGIAAVVGCSVFMIFLCAYLIRYREFFKDSVIDLLTCRWVRYCSCSCKCSCKCISGPCSRCCSACYKETMIYDMVQYGHRRRPGHGDDPDRVICEIVESPPVSAPTVFVPPPSEESHQPVIPPQPPTPTSEPKPKKGRAKDKPKGRPKNKPPCEPTVSSQPPSQPTAMPGGPPDASPPAMPQMPPGVAEAVQAAVQAAMAAALQQQQQHQTGT
What are the official names of this protein?
Protein UL133.
What are the subcellular locations of this protein?
Host Golgi apparatus membrane; Multi-pass membrane protein.
Protein: RL14_DICT6
Sequence: MIMPQTRLVVADNTGAKEIMCFRILGKKRVAQVGDIIVASVKEAVPRSNIKKGDVVYAVVIRTKRTIKRKDGSCVRFDDNAAVIIDKEGNPKGTRVFGPVARELRDKNFMKIISLATEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: MKAR_ASPNC
Sequence: MDFLTKHLDCLSNWQLNLQPGWQTVGASALLAAGSLFVVSRALVFVRVLLSLFVLPGKPLRSFGPKGSWAVVTGASDGLGKEFALQLARADFNILLVSRTASKLDTLSNEITTKFPSVQTKTLAMDFARNQDSDYEKLKELVDELDVSVLVNNVGKSHSIPTPFALTPEDEMTDIVTINCLGTLRATQLVVPGMMQRKRGLVLTMGSFGGLLPTPLLATYSGSKAFLQQWSTSLGSELEPYGITVELVQAYLITSAMSKIRRTSATIPDPRSFVKSVLTKIGRNGGSPTYAYSSSPYWSHGLMAWFLTCVTGTMGKIVVSQNKGMHESIRKRALRKAEREKGKKST
What is the function of this protein?
Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate.  Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation.  VLCFAs serve as precursors for ceramide and sphingolipids.
What are the official names of this protein?
Very-long-chain 3-oxoacyl-CoA reductase, 3-ketoacyl-CoA reductase, 3-ketoreductase, KAR, Microsomal beta-keto-reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: NU1M_DROPE
Sequence: MFYMEFILSLIGSLLLIICVLVSVAFLTLLERKVLGYIQIRKGPNKVGLMGIPQPFCDAIKLFTKEQTYPLLSNYLSYYISPIFSLFLSLFVWMCMPFFVKLYSFNLGGLFFLCCTSLGVYTVMIAGWSSNSNYALLGGLRAVAQTISYEVSLALILLSFVFLIGSYNMMYFFYYQIYIWFLIILFPMALVWLTISLAETNRTPFDFAEGESELVSGFNVEYSSGGFALIFMAEYASILFMSMLFCVIFLGCDVFNLLFYVKLTFISFVFIWARGTLPRFRYDKLMYLAWKCFLSFSLNYLLFFIGFKILLFSFL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HIS1_CAMJD
Sequence: MQENTRLRIAIQKSGRLSKESMKLLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELKRQSLGENPNYKLLKKLDFGFCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCMLTGSIEVAPRANLADAICDLVSSGATLQANNLKEIKVIYESRACLIQKENALIKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLAHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_BIFA0
Sequence: MPTFTREEIVHLGDLARIALTDEEITRMQSELNVIADAIDSVQEVATADVEPTANPVPLEAYLRPDVPATPLTQAEALSGAPVAEDGMFVAPRILGEE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: MIC13_DROME
Sequence: MVLGFLVRGGLVAATVYYTQKVGIWGDSDQTDKLYNDIKSELRPHVQKLEKQLPFEVPQLPKTGEMRFLAKHYYNEGVKNTFRFIHMLPCYAGRGLKKVKDTFQDFAQSPAIAGGAESSPPK
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
What are the official names of this protein?
MICOS complex subunit MIC13 homolog QIL1.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic13 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein. Note=Enriched at crista junctions.
Protein: FOLD_CROS8
Sequence: MAAKIIDGKTIAQQVRLEVAEKVKARVAAGKRAPGLAVVLVGANPASQIYVGSKRKACEEVGFVSRSYDLPETTSEAELLALIDELNADAAIDGILVQLPLPAGIDNVKVLERIAPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTYGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRQHVENADLLIVAVGKPGFIPGEWIKEGAIVIDVGINRLENGKVVGDVVFEEAAKRASYITPVPGGVGPMTVATLIQNTLQACVEYHDGEEA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: FLZ6_ARATH
Sequence: MLLGKRQRPPINRTTSLSEIKFDLNLPSESEPSNQQKPTVASPYGSNGQAVTAAVDQNRGFLDQRLLSMVTPRGNLRRHSGDFSDAGHFLRSCALCERLLVPGRDIYMYRGDKAFCSSECRQEQMAQDERKEKGKSAAPAKEPAVTAPARAKPGKGRAAAAV
What is the function of this protein?
May act as an adapter to facilitate the interaction of SnRK1 complex with effector proteins, conferring tissue- and stimulus-type specific differences in the SnRK1 regulation pathway (PubMed:24600465).  Negatively regulates KIN10 leading to a repression of the SnRK1 signaling pathway (PubMed:29406622).
What are the official names of this protein?
FCS-Like Zinc finger 6.
What is the protein family that this protein belongs to?
Belongs to the FLZ family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Endoplasmic reticulum. Note=Shuttles from the cytoplasm to the nucleus when associated with KIN10 (PubMed:24600465). Co-localized with ER marker when associated with KIN11 (PubMed:29406622).
Protein: ATPD_DINSH
Sequence: MSDSASISSGIADRYATAIFELAKEENNIGALEAGADLLDAALKESAEFRDLISSPVYSRDEQAGAIGAIAKKLELAPMLSNALALMASKRRLFVLPQLVASLRALIAEEKGEMTADVISAQPLSKANLDELTKVLSASADKTVKVNATVDNSLIGGLVVKMGSKMIDTSIRAKLNALQNTMKEVG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.