PharMolix/UniProtQA huggingface dataset:
Protein: ASTE_YERPE
Sequence: MLDFLAITLSGKPPQVIQGETVNLKWQWLGEGILTLVPHRSYTQSVVISAGIHGNETAPIEILNQLVTDLLAGQLPLSVRLLVLLGNPPAIRKGKRYLSNDINRMFGGRYQHYTPSDETRRASTLEQRVMAFFQASHTSERLHYDLHTAIRGSYHPRFGLLPYQQTPYSAAMFRWLRDIELDALVMHTSAGGTFAHFSSERCQAASCTLELGKALPFGENQLSQFSAITQGLRSLVSDSALPARKTENMKYYRVVKSLLRQHPDFKLRVAEDTVNFTRFAQGTLLTEQPNDNYRVEHPYEWILFPNPHVALGLRAGMMLVKMCESELPIT
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: PTEA_GEOSE
Sequence: MQTYEQTVFQLILHGGNGRSYAMEAITAAKKGEFAEARRLLEQAGAELQAAHGLQTALLQQEASGGQPVVTLLMVHAQDHLMTAITVKDLAAEFVELYEALKRQTTES
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II CelABD PTS system is involved in cellobiose transport.
What are the official names of this protein?
PTS system cellobiose-specific EIIA component, Cellobiose-specific phosphotransferase enzyme IIA component, EIIA-Cel, EIII-Cel.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAK5_COCIM
Sequence: MAQKRSHNHKDHTAKAIKRRKFNAATAKSSDDAAHDIVSVDQLDWKTVTLPDRLDDAEGFYGLEEIEGVDILRPSGGGEIKFKASKSKIKGILKNSTDKSGQPAEDWEEWSGFGDDSEDGDGTTLEAEKKAENHGKVNDRRTKTNNSNKEKESNKLPKDRGPRIKTDNGIKTGVSFAALQDEVEEDVDVSAWDSLDLSAELQTSLGRLKFSSPTPIQSACIPAVLQGHDVIGKASTGSGKTLAFGIPIVEYFLGKYRGGRAPTASEERESTKEPMALILSPTRELAHQLNKHLTDLVNHAPNTQVRIATVTGGLSIYKQQRLLADADIIIATPGRLWEVVGSMTGFLSKLKKIRFLVIDEADRLLSEGHFKEVEEILNAIDKVEITEEAYGERSEREPEPEPDEEKKAEPRQTLVFSATFHKGLQQKLSGKIRYRNDDLLDKKESMEYLLRKLNFREERPKFIDVNPISQMAQNLKEGLVQCAPMDKDLLLYTLLLYHPKHRTLVFTNSISAVRRLTQLLQNLNLPTFALHSSMAQKARLRSVERFSSLSSDPSSILVATDVAARGLDIKGIDLIVHYHIPRTADTYVHRSGRTARASASGKSILICAPEETTGVARLVAKIHSNKKDSSATESKMEKKVPLQSVDLDRRIIDRLRPRVTLAKKITESILAKEKLSSEDDWLRSAAEDLGVDYDSDEFAEQQSKGKGKGRGRGGGRQAREQKAASLSKAELAGLKAQLRELVSKKVNVGISEKYLTAGRVDVDALLRGEGNDAFLGHVEKLSF
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase MAK5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX24/MAK5 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: GLBP1_GLYDI
Sequence: MHLTADQVAALKASWPEVSAGDGGAQLGLEMFTKYFHENPQMMFIFGYSGRTEALKHSSKLQHHGKVIIDQIGKAVAEMDNAKQMAGTLHALGVRHKGFGDIRAEFFPALGMCLLDAMEEKVPGLNRTLWAAAYREISDACIAGLQS
What are the official names of this protein?
Globin, major polymeric component P1.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: YCP8_SCHPO
Sequence: MSTTNKIYFIAGGNRGIGLSLVKELSNRKGTVVFASARKPGAATKLQEWSKSHSNVHIIKLDVSSLESANEAAQEVTKVVDAVDVLWVNSAVFHSFGPVVNTPDDVWNSHYKTNVLGPIHVYQAFYPLIKKGRSKIIVFTSSLAGSMGAFFPSSQSAYGQSKAALNYTMKEISFELQDEGFIVISIHPGAVRTDSAQEIVNQHAEKKPEILDLFAKQALTPEKSASDMLKVVDNLKPENNGLFYNYDGTIIPF
What are the official names of this protein?
Uncharacterized oxidoreductase C663.08c.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TNR17_MOUSE
Sequence: MAQQCFHSEYFDSLLHACKPCHLRCSNPPATCQPYCDPSVTSSVKGTYTVLWIFLGLTLVLSLALFTISFLLRKMNPEALKDEPQSPGQLDGSAQLDKADTELTRIRAGDDRIFPRSLEYTVEECTCEDCVKSKPKGDSDHFFPLPAMEEGATILVTTKTGDYGKSSVPTALQSVMGMEKPTHTR
What is the function of this protein?
Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL.  Promotes B-cell survival and plays a role in the regulation of humoral immunity.  Activates NF-kappa-B and JNK (By similarity).
What are the official names of this protein?
Tumor necrosis factor receptor superfamily member 17, B-cell maturation protein.
What are the subcellular locations of this protein?
Membrane; Single-pass type III membrane protein.
Protein: PICAL_HUMAN
Sequence: MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDMSTFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRTPTHEMFVGFTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVSGAQIQFM
What is the function of this protein?
Cytoplasmic adapter protein that plays a critical role in clathrin-mediated endocytosis which is important in processes such as internalization of cell receptors, synaptic transmission or removal of apoptotic cells.  Recruits AP-2 and attaches clathrin triskelions to the cytoplasmic side of plasma membrane leading to clathrin-coated vesicles (CCVs) assembly (PubMed:10436022, PubMed:16262731, PubMed:27574975).  Furthermore, regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature (PubMed:25898166).  In addition to binding to clathrin, mediates the endocytosis of small R-SNARES (Soluble NSF Attachment Protein REceptors) between plasma membranes and endosomes including VAMP2, VAMP3, VAMP4, VAMP7 or VAMP8 (PubMed:22118466, PubMed:21808019, PubMed:23741335).  In turn, PICALM-dependent SNARE endocytosis is required for the formation and maturation of autophagic precursors (PubMed:25241929).  Modulates thereby autophagy and the turnover of autophagy substrates such as MAPT/TAU or amyloid precursor protein cleaved C-terminal fragment (APP-CTF) (PubMed:25241929, PubMed:24067654).
What are the official names of this protein?
Phosphatidylinositol-binding clathrin assembly protein, Clathrin assembly lymphoid myeloid leukemia protein.
What is the protein family that this protein belongs to?
Belongs to the PICALM/SNAP91 family.
What are the subcellular locations of this protein?
Cell membrane. Membrane, clathrin-coated pit. Golgi apparatus. Cytoplasmic vesicle, clathrin- coated vesicle. Nucleus. Note=Colocalized with clathrin in the Golgi area (PubMed:10436022). Interaction with PIMREG may target PICALM to the nucleus in some cells (PubMed:16491119).
Protein: TXND6_HUMAN
Sequence: MGSRKKEIALQVNISTQELWEEMLSSKGLTVVDVYQGWCGPCKPVVSLFQKMRIEVGLDLLHFALAEADRLDVLEKYRGKCEPTFLFYAGGELVAVVRGANAPLLQKTILDQLEAEKKVLAEGRERKVIKDEALSDEDECVSHGKNNGEDEDMVSSERTCTLAIIKPDAVAHGKTDEIIMKIQEAGFEILTNEERTMTEAEVRLFYQHKAGEEAFEKLVHHMCSGPSHLLILTRTEGFEDVVTTWRTVMGPRDPNVARREQPESLRAQYGTEMPFNAVHGSRDREDADRELALLFPSLKFSDKDTEAPQGGEAEATAGPTEALCFPEDVD
What is the function of this protein?
May be a regulator of microtubule physiology.
What are the official names of this protein?
Thioredoxin domain-containing protein 6, Thioredoxin-like protein 2, Txl-2.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Dynein axonemal particle. Note=Associated with microtubules. Detected in cilia of lung epithelium, and associated with the spermatid tail and manchette.
Protein: DPOL_THEFM
Sequence: MILDTDYITEDGRPVIRVFKKENGEFKIEYDRDFEPYIYALLKDDSAIEDVKKITASRHGTTVRVVRAGKVKKKFLGRPIEVWKLYFTHPQDVPAIRDKIREHPAVVDIYEYDIPFAKRYLIDKGLIPMEGDEELKMLAFDIETLYHEGEEFAEGPILMISYADEEGARVITWKKIDLPYVDVVSTEKEMIKRFLKVVKEKDPDVLITYNGDNFDFAYLKKRSEKLGVKFILGRDGSEPKIQRMGDRFAVEVKGRIHFDLYPVIRHTINLPTYTLEAVYEAIFGQPKEKVYAEEIAQAWETGEGLERVARYSMEDAKVTYELGREFFPMEAQLSRLVGQSFWDVSRSSTGNLVEWYLLRKAYERNELAPNKPSGRELERRRGGYAGGYVKEPERGLWENIAYLDFRCHPADTKVIVKGKGVVNISEVREGDYVLGIDGWQKVQRVWEYDYEGELVNINGLKCTPNHKLPVVRRTERQTAIRDSLAKSFLTKKVKGKLITTPLFEKIGKIEREDVPEEEILKGELAGIILAEGTLLRKDVEYFDSSRGKKRVSHQYRVEITVGAQEEDFQRRIVYIFERLFGVTPSVYRKKNTNAITFKVAKKEVYLRVREIMDGIENLHAPSVLRGFFEGDGSVNKVRKTVVVNQGTNNEWKIEVVSKLLNKLGIPHRRYTYDYTEREKTMTTHILEIAGRDGLILFQTIVGFISTEKNMALEEAIRNREVNRLENNAFYTLADFTAKTEYYKGKVYDLTLEGTPYYFANGILTHNSLYPSIIISHNVSPDTLNREGCGEYDEAPQVGHRFCKDFPGFIPSLLGDLLDERQKVKKHMKATVDPIEKKLLDYRQRAIKILANSFYGYYGYAKARWYCKECAESVTAWGRQYIETTMREIEEKFGFKVLYADSVTGDTEVTIRRNGRIEFVPIEKLFERVDHRVGEKEYCVLGGVEALTLDNRGRLVWKKVPYVMRHKTDKRIYRVWFTNSWYLDVTEDHSLIGYLNTSKVKPGKPLKERLVEVKPEELGGKVKSLITPNRPIARTIKANPIAVKLWELIGLLVGDGNWGGQSNWAKYYVGLSCGLDKAEIERKVLNPLREASVISNYYDKSKKGDVSILSKWLAGFMVKYFKDENGNKAIPSFMFNLPREYIEAFLRGLFSADGTVSLRRGIPEIRLTSVNRELSDAVRKLLWLVGVSNSLFTETKPNRYLEKESGTHSIHVRIKNKHRFADRIGFLIDRKSTKLSENLGGHTNKKRAYKYDFDLVYPRKIEEITYDGYVYDIEVEGTHRFFANGILVHNTDGFFATIPGADAETVKKKAREFLNYINPKLPGLLELEYEGFYRRGFFVTKKKYAVIDEEGKITTRGLEIVRRDWSEVAKETQARVLEAILRHGDVEEAVRIVKEVTEKLSKYEVPPEKLVIHEQITRELKDYKATGPHVAIAKRLAARGIKVRPGTVISYIVLKGSGRIGDRTIPFDEFDPTKHRYDAEYYIENQVLPAVERILKAFGYKKEDLRYQKTRQVGLGAWLKMGKK
What is the function of this protein?
PI-TfuII is a highly active homing endonuclease using Mg(2+) as cofactor.  Its minimal recognition and cleavage site is 21 bp (5'-ACGCGGATACAGACGGCTTTT-3') cutting after -7 on both linear or circular DNA substrates.  Yields 5'-phosphate and 3'-OH ends.  Its endonuclease activity is strongly inhibited by the 3' digestion product, which remains bound to the enzyme after the cleavage reaction.
What are the official names of this protein?
DNA polymerase, Pol Tfu.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
Protein: FEN11_SORBI
Sequence: MGIKGLTKLLADNAPKAMKEQKFESYFGRKIAIDASMSIYQFLIVVGRTGMETLTNEAGEVTSHLQGMFNRTIRLLEAGIKPVYVFDGKPPDMKKEELAKRFSKREDATNDLKEAVEAGDKDAVEKLSKRTVKVTAQHNDDCKRLLRLMGVPVVEAPSEAEAECAALCKNDKVFAVASEDMDSLTFGAPRFLRHLMDPSSKKIPVMEFDVAKVLEELELTMDQFIDLCILCGCDYCDSIKGIGGQTALKLIRQHGSIESILENLNKDRYQIPEDWPYQEARRLFKEPNVTLDVPELKWTPPDEEGLISFLVKDNGFNEDRVTKAIEKIKSAKNKSSQGRLESFFKPVATTSAPLKRKETSDKTSKAAAANKKTKAGGKKK
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1-A, FEN-1-A, Flap structure-specific endonuclease 1-A.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: RL39_PYRCJ
Sequence: MARNKPLGKKLRLAAALNSNRNPPLWVIAKTKRRVTRSPARRHWRRQKLKA
What are the official names of this protein?
50S ribosomal protein L39e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL39 family.
Protein: Y444_KLEP7
Sequence: MFGGKGGLGNLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKVTINGAHNCRRVEIDPSLLEDDKEMLEDLVAAAFNDAARRIEETQKEKMASVSAGMQLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein KPN78578_04440.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: FAXC_XENTR
Sequence: MHWGVGLVSSRSCVVDLSRNQTLSLCWCWGSEENYSFYGDIVAFPLQDYGGVMSGLGSDSWWKKTLYLTGGALLAAAAYLLHELLAIRKEQEVNSKDAIILHQFSRPNNGVPSLSPFCLKIETYLRMADLPYQNYFDGKLSPQGKMPWIEYNHTRVSGTEFIIDFLEEKLGVNLNKHLNPHQRAVSRAVTKMVEEHFYWTLAYCQWVENLDETQKMLNITGPLSDLLKWILCHLTKGIVKREMYGQGIGRFSEEEIYRLMEKDMRSLAGLLGDKKYLMGPKFSTLDATVFGHIANALWGTQGTYKEEGIAGELINLAMYCERIRRKFWPEWHDDNDNTTYESDDSGEDSRTHTPFQDFSYYSRTGTFEDDGMDNSISQTPDTDFTGHSLFDSDVDMDEFTDHDQCK
What is the function of this protein?
May play a role in axonal development.
What are the official names of this protein?
Failed axon connections homolog.
What is the protein family that this protein belongs to?
Belongs to the FAX family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GCST_SHEB9
Sequence: MANKTILFNKHLESNAKMVDFHGWDMPLNYGSQIEEHNAVRQDAGMFDVSHMTVVDVIGNDACAFLRKLLANDVAKLKVPGKALYGGMLDENAGVIDDLITYYLTDTNYRVVVNSATREKDLAWIAKQSQGFDVTVTERPELAMIAVQGPNAKAKAAAVLSAEQNAAIEGMKPFFGKQAGSLFIATTGYTGEAGYEIIVPEDEAQAMWQALLDQGVKPCGLGARDTLRLEAGMNLYGLDMDETINPLAANMGWTIAWEPSDRDFIGRKALETLRDAGTDKLVGLVMEEKGVLRHDMPVFFTDSAGVEHQGVITSGTFSPTLGYSIAMARVPNSIGDTAEVEMRKKRVAVRVVAPNFVRNGKQAF
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: AHPD_COXB2
Sequence: MLQTYKDQLPDYAKDLKLNLTQVLSESPSSELSNQQITGVALAVAYATRNRQLIELIFQKAEAELDESTLQAIKAAASIMAMNNIYYRFVHLVKDSEYQRLPANLRMNIIANPGIDKKDFELYSLAVSAINGCGLCIDAHANTLIKAGFSKHSIQHVIRIAAVLNGLAQVSIIENKT
What is the function of this protein?
Antioxidant protein with alkyl hydroperoxidase activity.  Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
What are the official names of this protein?
Alkyl hydroperoxide reductase AhpD, Alkylhydroperoxidase AhpD.
What is the protein family that this protein belongs to?
Belongs to the AhpD family.
Protein: PTYBC_ECO57
Sequence: MAKEISSELLNTILTRVGGPGNIASCGNCMTRLRLGVHDSSLVDPDIKTLEGVKGVILTSDQVQVVFGPGKAHRAAKAMSELLGEAPVQDAAEIAAQNKRQLKAKQTSGVQQFLAKFATIFTPLIPGFIAAGLLLGIATLIATVMHVPADAQGTLPDALNFMKVFSKGLFTFLVILVGYNAAQAFGGTGVNGAIIAALFLLGYNPAATTGYYAGFHDFFGLPIDPRGNIIGVLIAAWACARIEGMVRRFMPDDLDMLLTSLITLLITATLAYLIIMPLGGWLFEGMSWLFMHLNSNPLGCAVLAGLFLIAVVFGVHQGFIPVYLALMDSQGFNSLFPILSMAGAGQVGAALALYWRAQPHSALRSQVRGAIIPGLLGVGEPLIYGVTLPRMKPFITACLGGAAGGLFIGLIAWWGLPMGLNSAFGPSGLVALPLMTSAQGILPAMAVYAGGILVAWVCGFIFTTLFGCRNVNLD
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in N-acetylmuramic acid (MurNAc) transport, yielding cytoplasmic MurNAc-6-P.  Is also able to take up anhydro-N-acetylmuramic acid (anhMurNAc), but cannot phosphorylate the carbon 6, probably because of the 1,6-anhydro ring.
What are the official names of this protein?
PTS system N-acetylmuramic acid-specific EIIBC component, EIIBC-MurNAc.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NADE_CHLTE
Sequence: MKPQNLHFDYGLVEAILVPFIRNEIRKFGFGSVVLGLSGGIDSAVVCELAVRALGVENVLALMMPYKTSSQESLDHAELMVDRLGIRYEIMPVTEVVDAFFATRPDASRLRRGNVMARSRMLCLYDVSARDGCLVLGTSNKTELMLGYGTMFGDMASAVNPIGDLYKTQIFGLARHLGIPAPLIDKPPSADLWEGQSDEADLGFSYEEVDQLLYMMLEERMDRDAILAEGIDSAFYQRVRSMVVRNQYKRMMPVIAKLSSRTPGIDFRYARDWQEVR
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: DEF1_BACCR
Sequence: MAVLEIIKHPNEVLETPCERVINFDKKLVKLLKDMHETMLIADGVGLAAPQVGVSLQVAVVDVDDDTGKIELINPSILEKRGEQVGPEGCLSFPGLYGEVERADYIKVRAQNRRGKVFLLEAEGFLARAIQHEIDHLHGVLFTSKVTRYYEENELE
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase 1, PDF 1, Polypeptide deformylase 1.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: US22_HCMVA
Sequence: MSLLTKAAAEAWGTYLRQRDERCEDAIRCDYGVFQFRNTVFQKTLSMLQGLYLRQYDPPALRTYVQRHQGTTVALRNPANWFLVMREQAAIPQIYARSLAADYLCCDDTLEAVGVLAVRPPDSDLTRNTKQAQELPCVLMLSHYGTVYVYDWETDGLYEVASDIKAFSKNGLLWCEYVYRHPQTPFATTEPRYHVQKFLCTDPTDAAAVAKTAREMSGLNLVIRTPGRTEVEPLLMLGSIEGLRACRPFDHMPAADFRDLLNFIRQRLCCEWYVVGLVGYYLAYGPFVPSGLVLLDKFGVVYLHKIEDSDLYRIADNFHMFLKCGLLKLRGLCRFDRGLRGECRLEELPVCHHTLKRDVLRWHGALGTITRSQLESALDWFLRPTRGTDKVPNNSSAWGRTDLLPTGALQDNQNWAFPSHSVETLPALQGGLWEDNDETTQTVDGQRCFRMPKFFPPPMCRVPYNECGVELPGGDSSDEDESGRPRRIANRIGDTPETPCNSENEDDTTVEGTSGGPEAMDSQAPYPSEDSPTTEKEAWLQRGRRAKAMHARGHTLKQVPIPEPDQMGDDGPDPGP
What are the official names of this protein?
Early nuclear protein HWLF1, Tegument protein US22.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US22 family.
What are the subcellular locations of this protein?
Virion tegument.
Protein: EFG1_COLP3
Sequence: MADLSKYRNIGIFAHVDAGKTTTTERILKLTGQIHKTGEVHDGESTTDFMEQEAERGITIQSAAVSCFWNDHRFNVIDTPGHVDFTVEVYRSLKVLDGGVGVFCGSGGVEPQSETNWRYANDSKVARIIMVNKLDRLGADFYRVCKQVKDVLGANPLIMTLPIGTEDEFVGVVDLLSEKAYIWDDTGLPENYEVTDIPADMVEQAAEYRVKLIETALEVDEDMLMEFLEGEMVPTIEQIKACIRTGTRDMTFFPTYGASAFKNKGIQLILDAVVDYLPSPTDVNPQPLTDEEGTPNGEFAIVSADETFKALAFKITDDRFGTLTFVRIYSGTLKKGDTILNAATGKTERVGRMCEMQADDRNELTSAQAGDIIAIVGMKSNVQTGHTLCDPKHPIVLEAMVFPKPVISISVTPKDKGSTEKMGLAIGKMVAEDPTFKVETDIDSGETILSGMGELHLDIKVDILKRTYGVELEVGKPQVAYRETITTAIEDSYTHKKQSGGSGQFGKIDYRIKPGEPGSGFVFSSVVVGGNVPKEFFPAIEKGFKGMMDTGVLAGFPVLDVEIELYDGGFHAVDSSAVAFELAARGAFRQSIPKAGAQLIEPIMKVDVFTPDDHVGDVIGDLNRRRGMIGGQEAGVSGVRIKADVPLSEMFGYIGTLRTMTSGRGQFSMEFSHYMPCPNNVAEIVIAEVKAAKIAKDAARK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 1, EF-G 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLP1_MORAL
Sequence: MIVPIFFLFSLLFSSSHGAIQDFCVADYSAPQGPAGYSCKNPAKVTVDNFVYSGLGITGNTTNLIKAAVTTAFDNQFPGVNGLGISLARPDLAPGGVIPFHTHPGASEIIIVIEGSLCAAFVSSDNKVYLKSLKKGDTMIFPSGLLHFQLNAGKNNALFFVAFNSPNPGLQLVDYALFGNDLATELVAAASFLDPAEIKRLKAVLGGSG
What is the function of this protein?
Has antibacterial activity against B. subtilis (MIC=5 ug), B. cereus (MIC=50 ug), A. hydrophila (MIC=2. 5 ug), S. marcescens(MIC=10 ug), S. enterica (MIC=10 ug), P. entomophila (MIC=2. 5 ug) and P. rhodesiae (MIC=10 ug).  Has antifungal activity against F. solani KACC 40384 and F. oxysporum KACC 40032.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Germin-like protein, Ma-Glp.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: XYNA_ASPFN
Sequence: MVSFSSILLACSAAIGALATPIEPLADHPNEAFNETAFNDLVGRSTPSSTGYNNGYYYSFWTDGGGDVTYTNGNGGSYSVQWSNVGNFVGGKGWNPGSSRAITYSGSFNPSGNGYLAVYGWTTDPLIEYYIVESYGTYNPGSGGTYKGQVTSDGGTYNIYTSVRTNAPSIIGTATFTQFWSVRTSKRVGGTVTTGNHFNAWAKYGLTLGTHNYQIVATEGYQSSGSSAITVY
What is the function of this protein?
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Probable endo-1,4-beta-xylanase A, Xylanase A, 1,4-beta-D-xylan xylanohydrolase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 11 (cellulase G) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNPA_RHOBA
Sequence: MSRTGGKRPLEFPKSSRVVRSSEFTKALRRGGVAANDCLVVFALPHDVPDADGEPSPDESKTVKCRLGVTIPKKTGNAVVRNRWKRLIREAFRLNQTQLPSGFDYVVRPKKDVTADWKMIEKGFVKLVGRAVRRSQSSADRSSTRS
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: KTHY_ALIF1
Sequence: MSKFIVIEGLEGAGKSTAIKNVLATLAKHGITSPVTTREPGGTPLAEKMRELVKQGHPDEPLTDMAELLLLYAARAQLVGNVIKPALARGEWVVGDRHDLSSQAYQGGGRGFDRELMMTMRNTVLGDFKPDLTIYMDIDPKLGLQRASARGELDRIEQMKLDFFERSRERYLEFANSDESIITIDAGQDLETVTNSIITALEAWLVKNGN
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: ATP8_CAVPO
Sequence: MPQLDTSTWFTVILSMIISLFMLLQLKISSHSFYLDPKTMSLKTTKHNLPWENKWTKTYLPLSLHLH
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: RRG9_COCP7
Sequence: MFGITSRPYHRWSSFAQALRILQSGTTLALELDHSSLFFSKRNITSCCHHTKPASHTPTSSNSIWTPSPLAESRLRSGYSLKPAHTNRVVTRRYASTTPKDSQPDPQAKTVSKRPAKKMEQWRLQKEALKKKFQEGWAPPKRLSPDAIEGVRELHQQNPQKFSTAVLAEHFKMSPEAIRRILKSKWRPSEKEMEKRRERWERRETRIWDHMSELGLRPLRKRPSSPASDKSSDAETRNRQPLHSIASTLLIQRDISPMWVLLLR
What is the function of this protein?
Required for respiratory activity and maintenance and expression of the mitochondrial genome.
What are the official names of this protein?
Required for respiratory growth protein 9, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RRG9 family.
What are the subcellular locations of this protein?
Mitochondrion.