PharMolix/UniProtQA huggingface dataset:
Protein: RD23B_RAT
Sequence: MQVTLKTLQQQTFKIDIDPEETVKALKEKIESEKGKDAFPVAGQKLIYAGKILSDDTALKEYKIDEKNFVVVMVTKPKAVTSAVPATTQQSSSPSTTTVSSSPAAAVAQAPAPTPALAPTSTPASTTPASTTASSEPAPTGATQPEKPAEKPAQTPVLTSPAPADSTPGDSSRSNLFEDATSALVTGQSYENMVTEIMSMGYEREQVIAALRASFNNPDRAVEYLLMGIPGDRESQAVVDPPPQAVSTGTPQSPAVAAAAATTTATTTTTSGGHPLEFLRNQPQFQQMRQIIQQNPSLLPALLQQIGRENPQLLQQISQHQEHFIQMLNEPVQEAGGQGGGGGGGGGGGGGGGGIAEAGSGHMNYIQVTPQEKEAIERLKALGFPEGLVIQAYFACEKNENLAANFLLQQNFDED
What is the function of this protein?
The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, Xpa, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex.  The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs.  The orientation of XPC complex binding appears to be crucial for inducing a productive NER.  XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery.  Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation.  Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair.  In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.  XPC:RAD23B contacts DNA both 5' and 3' of a cisplatin lesion with a preference for the 5' side.  Xpc:Rad22b induces a bend in DNA upon binding.  Xpc:Rad23b stimulates the activity of DNA glycosylases Tdg and Smug1 (By similarity).
What are the official names of this protein?
UV excision repair protein RAD23 homolog B.
What is the protein family that this protein belongs to?
Belongs to the RAD23 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RET4_RAT
Sequence: MEWVWALVLLAALGGGSAERDCRVSSFRVKENFDKARFSGLWYAIAKKDPEGLFLQDNIIAEFSVDEKGHMSATAKGRVRLLSNWEVCADMVGTFTDTEDPAKFKMKYWGVASFLQRGNDDHWIIDTDYDTFALQYSCRLQNLDGTCADSYSFVFSRDPNGLTPETRRLVRQRQEELCLERQYRWIEHNGYCQSRPSRNSL
What is the function of this protein?
Retinol-binding protein that mediates retinol transport in blood plasma.  Delivers retinol from the liver stores to the peripheral tissues (PubMed:4708098).  Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane (By similarity).
What are the official names of this protein?
Retinol-binding protein 4, Plasma retinol-binding protein, PRBP, RBP.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GBF2_ARATH
Sequence: MGSNEEGNPTNNSDKPSQAAAPEQSNVHVYHHDWAAMQAYYGPRVGIPQYYNSNLAPGHAPPPYMWASPSPMMAPYGAPYPPFCPPGGVYAHPGVQMGSQPQGPVSQSASGVTTPLTIDAPANSAGNSDHGFMKKLKEFDGLAMSISNNKVGSAEHSSSEHRSSQSSENDGSSNGSDGNTTGGEQSRRKRRQQRSPSTGERPSSQNSLPLRGENEKPDVTMGTPVMPTAMSFQNSAGMNGVPQPWNEKEVKREKRKQSNRESARRSRLRKQAETEQLSVKVDALVAENMSLRSKLGQLNNESEKLRLENEAILDQLKAQATGKTENLISRVDKNNSVSGSKTVQHQLLNASPITDPVAAS
What is the function of this protein?
Binds to the G-box motif (5'-CCACGTGG-3') of the rbcS-1A gene promoter.  G-box and G-box-like motifs are cis-acting elements defined in promoters of certain plant genes which are regulated by such diverse stimuli as light-induction or hormone control.  GBF2 is found to bind asymmetrically to the G-box.
What are the official names of this protein?
G-box-binding factor 2, bZIP transcription factor 54, AtbZIP54.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
Protein: KAX21_CENNO
Sequence: TIINVKCTSPKQCSKPCKELYGSSAGAKCMNGKCKCYNN
What is the function of this protein?
Blocks voltage-gated potassium channels (mKv1. 1/KCNA1 (Kd>25 nM), rKv1. 2/KCNA2 (Kd=2 nM), mKv1. 3/KCNA3 (Kd=1 nM), hKv1. 5/KCNA5 (Kd>25 nM) and mKv3. 1/KCNC1 (Kd>25 nM)) and calcium-activated potassium channels (KCa1. 1/KCNMA1 and KCa3. 1/KCNN4, Kd>25 nM).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 2.1, Noxiustoxin, NTx, Toxin II.11.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 02 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LIPB_MYCTO
Sequence: MTGSIRSKLSAIDVRQLGTVDYRTAWQLQRELADARVAGGADTLLLLEHPAVYTAGRRTETHERPIDGTPVVDTDRGGKITWHGPGQLVGYPIIGLAEPLDVVNYVRRLEESLIQVCADLGLHAGRVDGRSGVWLPGRPARKVAAIGVRVSRATTLHGFALNCDCDLAAFTAIVPCGISDAAVTSLSAELGRTVTVDEVRATVAAAVCAALDGVLPVGDRVPSHAVPSPL
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_STAAB
Sequence: MHYPEPISKLIDSFMKLPGIGPKTAQRLAFHTLDMKEDDVVQFAKALVDVKRELTYCSVCGHITENDPCYICEDKQRDRSVICVVEDDKDVIAMEKMREYKGLYHVLHGSISPMDGIGPEDINIPSLIERLKNDEVSELILAMNPNLEGESTAMYISRLVKPIGIKVTRLAQGLSVGGDLEYADEVTLSKAIAGRTEM
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: YICS_SALTI
Sequence: MKRKTLLLIATLVALPGVTYADSPFSSLQSAHEKNTILKDLRKMCTPKGALTDEAWEKKIMASEGNQQHIREAMIAIERNNQHNYWQALGKVECPEM
What are the official names of this protein?
Uncharacterized protein YicS.
Protein: RECA_MYCFA
Sequence: REKIGVMFGCFSYGTRVQLADGSTEKIGKIVNQKMDVEVMSYDPVTDQIVPRKVVNWFNNGPAEQFLQFTVEKSGGNGRSQFAATPNHLIRTPAGWTEAGDLIAGDRVLAAERHLLSDQQFQVILGSLMGGGNLSPNLHDRNGVRFRMGHGARQADYLEWKTALLGNIGHSVRENDQGARFVDFTPLPELGELRRAVYLGDGKKFLSEDYLKALTPLALAVWYMDDGSFTVRSKGVQQRTQGGSGRIEICVEAMAEGTRERLRDYLRDTHGLDVRLRSAGSGKSMLTFSTEATAKFQELVAPHMAPSMEHKLLPRFRGLGTVEPRFVEPAQRLVPARVLDVQVKPRTRSMNRFDIEVEGNHNYFVDGVMVHNSPETTTGGKALKFYASVRMDVRRIETLKDGSDAVGNRTRVKVVKNKVSPP
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity).
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPC_BUCBP
Sequence: MNSILKEIINDKLMWVKYHKKKQPLFTFQNKIVRSNYNFKNSLKSIHPSYILEIKKASPSLGIINNKLDLKKISLIYKKYASSISILTDEKYFHGNFEFIPIVRKIAHRQPILCKDFFIDPYQIYLARYYQADAILLMLSILNDNQYVFLRNIAEMLNMDVLTEIENKKELTRAINLKSKIIGINNRNLNNLSIDIQKTKVLAPLIPKKIIIISESGIQNYNQIRQLKPFVQGFLIGSNLMRKKNLEEAVCKMILGNNKICGLTQSSDVKIIKEYGIVYGGLIFCKFSPRYINCNNAYSIINNVSLKYIGVFCNENLKRVAYIGTKLSLHAVQLHGNEDQIYINNLKLILPKHIKIWKSIIYLDFLKNQKHLFYNVNKYIIDNKDGGSGKTFNWKYLKNCKLDNVILAGGLDINNCILATDLGCYGYDFNSKLESSPGIKDLKKIVALTYSLRRHTVFNYRNLICLGKK
What is the function of this protein?
Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway.  The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain (By similarity).
What are the official names of this protein?
Tryptophan biosynthesis protein TrpCF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the TrpF family.
Protein: DXS_BART1
Sequence: MSQVLTPLLDRVCFPQDLRALPESYLVQLANELRTETIDAVSVTGGHLGAGLGVVELTVALHYIFNTPEDRIIWDVGHQTYPHKILTGRREKIRTLRQEGGLSGFTKRVESVYDPFGAGHSSTSISAGLGMAVASALKEEKKRKVIAVIGDGAMSAGMAYEAMNNAGALNARLIVILNDNDMSIAPPTGSMSAHLARLVSRPSYRHLRERVKMLSEKLPKFFWDKARRSEEFARGLLVGGTLFDELGFYYVGPIDGHNLGHLLPVLKNVREYPHGPVLVHVVTHKGKGYPPAEASSDKYHGVNRFDVTTGKQVKASSNILPYTKVFSKALVEEACHDDKIVGITAAMPTGTGLDSFAEKFPEKMFDVGIAEQHAVTFAAGLACEGYKPFVAIYSTFLQRAYDQIIHDVSIQKLPVRFAIDRAGFVGADGATHAGSFDIVFLATLPEFVVMAPSDELELMHMVRTAAAYDQGPISFRYPRGEGIGIDLPQRGEILEIGKGRVLREGNRIALVCFGTRMSEVLRAADRLGAKGLSTTVADARFAKPLDKDLMRRLAREHEVLVTIEEGAIGGFGAHLLQFLAQEGLLEHGLKVRTLKFPDEYLNHGSPEKVLSTIGLDAMGIVNTVLTVVGREIRME
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: SRB8_YEAST
Sequence: MNNGSGRYLLTPPDDLHPYVPSSKPQEQVYPDFKPWEHTAAEDQILANFVAKGFYHTPMVNFESISARSSVHESLVTQSNILSQQFDKIIKIREDHINKIPSNSTTTLHGPGFQLPNRITLTDHRKETWLHELSSSHTSLVKIGKFIPHGLKRRQVIEQCYLKFIPLKRAIWLIKCCYFIEWKSNHKKKRSNAAGADDAISMHLLKDWTDTFVYILEKLIFDMTNHYNDSQQLRTWKRQISYFLKLLGNCYSLRLINKEIFHHWLVEFINKMENFEFLPLSLHILMIFWNDICQIDTNAPVAATITSSQKEPFFLVTKITDMLLHKYYIVSSSKSMINDENYIINDIKKNNKIKLNILKILSSLILKIFQEQSLEVFIFPTSNWEIYKPLLFEIVSNADTNQNSDMKKKLELISYRNESLKNNSSIRNVIMSASNANDFQLTIVTCKQFPKLSCIQLNCIDTQFTKLLDDNPTEFDWPTYVDQNPLTMHKIIQLILWSIHPSRQFDHYESNQLVAKLLLLRINSTDEDLHEFQIEDAIWSLVFQLAKNFSAQKRVVSYMMPSLYRLLNILITYGIIKVPTYIRKLISSGLLYLQDSNDKFVHVQLLINLKISPLMKSQYNMVLRNVMEYDVKFYEIFNFDQLVEITEQIKMRILSNDITNLQLSKTPLSIKIMVAEWYLSHLCSGILSSVNRTVLLKIFKIFCIDLEVFHHFFKWIEFIVYHQLLSDIESLEALMDILLCYQKLFSQFINDHILFTKTFIFIYKKVLKEKDVPAYNVTSFMPFWKFFMKNFPFVLKVDNDLRIELQSVYNDEKLKTEKLKNDKSEVLKVYSMINNSNQAVGQTWNFPEVFQVNIRFLLHNSEIIDTNTSKQFQKARNNVMLLIATNLKEYNKFMSIFLKRKDFTNKNLIQLISLKLLTFEVTQNVLGLEYIIRLLPINLENNDGSYGLFLKYHKEQFIKSNFEKILLTCYELEKKYHGNECEINYYEILLKILITYGSSPKLLATSTKIIMLLLNDSVENSSNILEDILYYSTCPSETDLNDIPLGSGQPDNDTVVTNDDKSDDDDHTVDEIDHVEYYVMMDFANLWVFQAFTCFCIKKIMENNEPAMAMEDLKNFIFQIIEITNSNDLCSQIFDQLKDMQTIEMITQIVEKDFCTSCLQNNNQKIDDNYIVVVIEIITSLSMRFQRETSGMIVISMENYHLLIKIIRQLSELNEGNLSKREIQIDAVLKIFSFHQDSIFQRIIADLSADKPTSPFIDSICKLFDKISFNLRLKLFLYEILSSLKSFAIYSSTIDAPAFHTSGKVELPKKLLNLPPFQVSSFVKETKLHSGDYGEEEDADQEESFSLNLGIGIVEIAHENEQKWLIYDKKDHKYVCTFSMEPYHFISNYNTKYTDDMATGSNDTTAFNDSCVNLSLFDARFERKNPH
What is the function of this protein?
Component of the SRB8-11 complex.  The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription.  The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator.  It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.  The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II RPB1 at serines 2 and 5.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 12, Mediator complex subunit 12, Suppressor of RNA polymerase B 8.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 12 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RR4_FUNHY
Sequence: MSRYRGPRVRIIRRLGVLPGLTNKTPQLKSSSPNQSAAKKISQYRIRLEEKQKLRFHYGITERQLLNYVRIARKAKGSTGQVLLQLLEMRLDNIVFRLGMAPTIPGARQLVNHRHVLVNDCIVDIPSYRCKPEDSITVKNRQKSQAIITKNIDFSQKAKVPNHLTFDSTQKKGLVNQILDRESIGLKINELLVVEYYSRQA
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL17_CHLAA
Sequence: MRHRHAGKLLGRSYEHRKALYRNLMIALIEHKKIKTTLAKARAVQPEVEALISIAREDTPHARRMALSKLASKEAMRKLFTFAPTTYGGRNGGYTRITKLGPRRGDGAEMALIELI
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: CLPX_ECOHS
Sequence: MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVISHRVETGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDESVIDGQSKPLLIYGKPEAQQASGE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: HIR3A_HIRME
Sequence: VVYTDCTESGQNLCLCEDSNVCGEGNKCILGSNGEKNQCVTGEGTPKPQSHNDGDFEEIPEEYLQ
What is the function of this protein?
Hirudin is a potent thrombin-specific protease inhibitor.  It forms a stable non-covalent complex with alpha-thrombin, thereby abolishing its ability to cleave fibrinogen.
What are the official names of this protein?
Hirudin-3A, Hirudin IIIA.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I14 (hirudin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: TDXH_THEKO
Sequence: MVVIGEKFPEVEVKTTHGVIKLPDYFAEQGKWFVLFSHPADFTPVCTTEFYAMQKRVDQFRELGVEPIGLSVDQVFSHIKWMEWIKENLGEEITFPVIADDRGELADKLGMIPSGATITARAVFIVDDKGIIRAIVYYPAEVGRDWDEILRLVKALKVSDEKGVALPHKWPNNELIGDKAIVPPASTVDEVKQREEAKAKGEIECYDWWFCYKKLE
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Peroxiredoxin, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Prx6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y6968_DICDI
Sequence: MNSEFSVGLSNTISSLFKDDEDYQIVQASELLTYLSNKGFYPPLVIQNIMIDILESERSNDPAVVYNIIKVLNSLKDEGYRIELENWDLIISVFISLNIHLSRPNSSSPPTTTTTTTTTGERAGKKLKTESSPTLSSSSLATSSRGVNTVSDSVAKIPFLSSKVLATYFISIYESMNMVTSSFTDSHPLHRLFKVGNRAHILFSEVMSIIDNCDHDTLREMSKFVTLIYRGGKSWEDSILPSISQGFRNIKRCYRRALFCQLMPFGDEKTKLLKGMLEYFYPTGSGNEFVGFNKRKRGGTKELIEELTPWFKKISTKAIKHCSKTPSSDDQFYDSYNYHDNQNDDNDTNYLNLESPIGEIEVFVIMICQLFQSTIISSTKQYGLKLKNQVQNKQQQQQQKLTSIIKDEDKNEKENKSENEEKEKEKEKEKEKEKEKEKEKEKENEEGEEDNGDQLPYQVPWQTVYEQFKEFSKTILTTCEKICKNRTLIESNLNGVETILKFKSTP
What are the official names of this protein?
Uncharacterized protein DDB_G0286423.
Protein: PRS8_DROME
Sequence: MTVTNRMEIESAYHKGEGFRSYYIQKIEELQLVVAEKHQNLRRLQAQRNELNAKVRMLREELQLLQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDLDKNIDINDVTPNCRVALRNESYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSSRIESGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDPALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK
What is the function of this protein?
The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins.  The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity).
What are the official names of this protein?
26S proteasome regulatory subunit 8.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GSA2_EXIS2
Sequence: MSLTNQNSKSKAAFERALPLMPGGVNSPVRAYKSVGMTPIFAERAQGSRLYDIDGKEYIDYVLSWGPMILGHADPIVTAAIQEQATRGWSYGTPTEIESAMAEVVISRVPSVEVVRMVNSGTEATMAALRLARGYTGKTKILKFEGCYHGHGDSLLIKAGSGVATLGLPDSPGVPAQIASMTLTVPYNDMDAVRIAFEKHGDDIAGVIVEPAAGNMGFVPPQPGFLEGLREITEQHGTLLIFDEVMTGFRVGFNCAQGHFGVTPDITCLGKVIGGGMPVGAYGGRRDIMEQIAPQGPIYQAGTLSGNPLAMAAGLATLTQLKPEHYEEFDRKANRLSEGYLAAAAKYNIPLTTNRAGAMFGVFFTDQPVTNFEQAKSSNLDMFRSYYQKMAARGVFLPPSQFEGLFLSTVHTDDDIEQTLAAVELTFKELQLEFNR
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 2, GSA 2, Glutamate-1-semialdehyde aminotransferase 2, GSA-AT 2.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_BORBR
Sequence: MRRVLYFTNTRPDAYATMSDPIRLIVGLGNPGPDYETTRHNAGFWLADHLADDLRTAFALEKGFFGMLAKARHAGENVVLLKPITYMNRSGQSVGAVARFYKLAPEQVLVLHDELDLLPGQVKIKQGGGHAGHNGLKDIQAALGSPNFWRLRIGIGHPRSLGLAQQVADFVLHPPRREEQQQIDTVIDRCRAVVPAMLAGDFALATRELHGANGA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTU_ACICJ
Sequence: MNRRLDNARTIRAPHGSDLSARSWLTEAPLRMLMNNLDPDVAERPEELVVYGGIGRAARDWESFDRILGALRDLGPEETLLVQSGKPVGVFRTHADAPRVLIANSNLVPNWANWQHFHELDRKGLMMYGQMTAGSWIYIGSQGIVQGTYETFVEAGRQHYGGDLAGRWILTGGLGGMGGAQPLAATMAGASMIAVECTPSRIEMRLRTRYLDRRADTLDEALAMLEAAKRDGKPVSIGLLGNAAEVFPELVRRGIRPDIVTDQTSAHDPVNGYLPAGWTLEHWAAMRERDPEAVALAAKRSMAGQVRAMLDFWRMGIPVLDYGNNIRAMAQEMGVADAFDFPGFVPAYIRPLFCRGIGPFRWAALSGDPEDIYRTDAKVKELIPDDPHLHHWLDMAREWIAFQGLPARICWVGLGQRHRLGLAFNEMVARGELSAPVVIGRDHLDSGSVASPNRETEAMRDGSDAVSDWPLLNALLNCASGATWVSLHHGGGVGMGYSQHAGMVIVADGTEAAAKRLERVLWNDPATGVMRHADAGYDIAIDCARENGLNLPGITG
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_CORGB
Sequence: MSAHCQVTGRKPSFGKSVSHSHRRTSRRWNPNVQRRKFYVPSEGRTITLTVSTKGLKVIDRDGIEAVVAQIRARGEKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: ACE_RABIT
Sequence: MGAAPGRRGPRLLRPPPPLLLLLLLLRPPPAALTLDPGLLPGDFAADEAGARLFASSYNSSAEQVLFRSTAASWAHDTNITAENARRQEEEALLSQEFAEAWGKKAKELYDPVWQNFTDPELRRIIGAVRTLGPANLPLAKRQQYNSLLSNMSQIYSTGKVCFPNKTASCWSLDPDLNNILASSRSYAMLLFAWEGWHNAVGIPLKPLYQEFTALSNEAYRQDGFSDTGAYWRSWYDSPTFEEDLERIYHQLEPLYLNLHAYVRRVLHRRYGDRYINLRGPIPAHLLGNMWAQSWESIYDMVVPFPDKPNLDVTSTMVQKGWNATHMFRVAEEFFTSLGLLPMPPEFWAESMLEKPEDGREVVCHASAWDFYNRKDFRIKQCTQVTMDQLSTVHHEMGHVQYYLQYKDQPVSLRRANPGFHEAIGDVLALSVSTPAHLHKIGLLDHVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPSSRYNFDWWYLRTKYQGICPPVVRNETHFDAGAKFHIPSVTPYIRYFVSFVLQFQFHQALCMEAGHQGPLHQCDIYQSTRAGAKLRAVLQAGCSRPWQEVLKDMVASDALDAQPLLDYFQPVTQWLQEQNERNGEVLGWPEYQWRPPLPNNYPEGIDLVTDEAEASRFVEEYDRSFQAVWNEYAEANWNYNTNITTEASKILLQKNMQIANHTLTYGNWARRFDVSNFQNATSKRIIKKVQDLQRAVLPVKELEEYNQILLDMETIYSVANVCRVDGSCLQLEPDLTNLMATSRKYDELLWVWTSWRDKVGRAILPYFPKYVEFTNKAARLNGYVDAGDSWRSMYETPTLEQDLERLFQELQPLYLNLHAYVGRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVAPFPSASTMDATEAMIKQGWTPRRMFEEADKFFISLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNMEDLVVVHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSINLLSSEGGGYEHDINFLMKMALDKIAFIPFSYLVDEWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPAPRSQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCKAAGHTGPLHTCDIYQSKEAGKRLADAMKLGYSKPWPEAMKVITGQPNMSASAMMNYFKPLMDWLLTENGRHGEKLGWPQYTWTPNSARSEGSLPDSGRVNFLGMNLDAQQARVGQWVLLFLGVALLLASLGLTQRLFSIRYQSLRQPHHGPQFGSEVELRHS
What is the function of this protein?
Isoform produced by alternative promoter usage that is specifically expressed in spermatocytes and adult testis, and which is required for male fertility (By similarity).  In contrast to somatic isoforms, only contains one catalytic domain (By similarity).  Acts as a dipeptidyl carboxypeptidase that removes dipeptides from the C-terminus of substrates (PubMed:7902354).  The identity of substrates that are needed for male fertility is unknown (By similarity).  May also have a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity).  The GPIase activity was reported to be essential for the egg-binding ability of the sperm (By similarity).  This activity is however unclear and has been challenged by other groups, suggesting that it may be indirect (PubMed:16270062).
What are the official names of this protein?
Angiotensin-converting enzyme, ACE, Dipeptidyl carboxypeptidase I, Kininase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase M2 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cytoplasm. Note=Detected in both cell membrane and cytoplasm in neurons. SUBCELLULAR LOCATION: [Angiotensin-converting enzyme, soluble form]: Secreted. SUBCELLULAR LOCATION: [Isoform Testis-specific]: Cell membrane; Single-pass type I membrane protein. Secreted. Note=The testis-specific isoform can be cleaved before the transmembrane region, releasing a soluble form.
Protein: OAZ_SCHJP
Sequence: MAFRNPIYQLSNTEDLNLDIINAPSLENSRRSSATLAVCTTEDSKFLYGTTPSGGAEWCSEGINSVRPSKRLLRRRRHVPRWISDSFRTCLPKSSGNLKEQALQPSLDRNPCRNGQADEALRNKRIGIAEPSNYWHGIIEETYDEHHQRQRNLHLIPENWQDVNLKNGLVAIIDLATDHLQCSKLIIYVDKHLPNLPYLVKSFHWVGFEPIAHPNCVDHAVFGMDL
What is the function of this protein?
Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis in response to increased intracellular polyamine levels.  Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome.
What are the official names of this protein?
Ornithine decarboxylase antizyme, ODC-Az.
What is the protein family that this protein belongs to?
Belongs to the ODC antizyme family.
Protein: YE95_SCHPO
Sequence: MSWRPTHSVRNAPYSMRDNYAQGVDVYYKKVGGTYRNLHFRGLRLLLLQCLSHFWDHDEKFKSHGLHVIDLACGSGEVSETVIEWEHLGRELGIHGGAFKVRKEISIRSIPPELPPFELIATDPFTLEAYTNRIGKPCLTLNFQDIADEKLPPSSAEDGIYDLVICSFALHLLTEPSKLFSTCYALSVQCRWLLVLGPHKKPELKPEWGWDAWNIDTWCPLGYGISHDYVLERVHARFFKSRNLIDG
What are the official names of this protein?
Uncharacterized protein C17A5.05c.
Protein: TRMA_ACIBS
Sequence: MTSSYRQQLQAKIDRITTQFSEFTPPTLEVFESPEQHFRMRAEFRIWHTENDMFYAMFERNDDGKQKTVVRIDEFPIADKSINDLMPLLLAELKANSLLSQRLFEVDFLATLSGEMLVTLIYHRKLNQEWEQAAKALAEKLNIKIMGRSRGQKIVIGDDFVVEEFELLNRSFKYKQIESSFTQPNAQVCKKMLQWACDAAEGSKKHLLELYCGNGNFTLPLSLKFERVLATELAKSSVYAAQWNIEQNQIDNIQVARLSAEEFTQAYQGEREFRRLQEADIDIQSYDFGTVFVDPPRAGIDDETLKLLQGFERIIYISCNPDTLYENLKTLTQTHRVTKFALFDQFPYTHHVESGVLLEKI
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.