PharMolix/UniProtQA huggingface dataset:
Protein: CART_DROME
Sequence: MSDIEDNDGDEYDELSELRQRHKPESQPSVDEAFDLDDLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLFMADTPDDYWCRIPELLDLPLEQRKSLSIPKELDNDELVYSKCYTYGVNWTQLLESGEEDDLTTMEPNASWPLIKCPQGWEYNTSVVWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLAGSLMTSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTCTFYTSGIMLLSGVTYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREFPEAVHLKLEAQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITLSWFANETVYLGLSYYGPALGTNQYVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVITVMLPDDAVDETLVLYLVSKALLSASFLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLKLPLVIMGFLSMLGGMTGLRLPETLHHRLPQTIEEGEEFGKNWQFKDCCRCAQKPEILSQPASYENLDVLAGSSTNASEVELELRDSRRVREPAPRIDERTPLDTTASGSGRPVHRPSMKRLVRQMSVMDTQRTHDGTMQLTHWI
What is the function of this protein?
Carcinine transporter which is required for recycling of the neurotransmitter histamine in photoreceptor neurons of the compound eye.  Following histamine release from photoreceptors and its uptake by glia where it is converted to carcinine, required for the uptake of carcinine from glia into photoreceptor cells where it can be hydrolyzed by tan to form histamine and beta-alanine.
What are the official names of this protein?
Carcinine transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, axon. Note=Expressed predominantly in photoreceptor axon termini.
Protein: RL24_LIMRJ
Sequence: MFIKTGDKVRVIAGKDKGKEGTIKKVLASQNRVIVEGVNIVKKHQKPSNSNPNGGVIDTEAAINASNVMLIDPSTNEPTRVGYKFVDGKKVRVAKKSGKTLD
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: PSAA_SYNE7
Sequence: MTISPPEREAKVKATVDKNPVPTSFEKWGKPGHFDRTLAKGPKTTTWIWNLHANAHDFDSHTSDLEDISRKIFSAHFGHLAVIFIWLSGAYFHGARFSNFSGWLADPTHVKPSAQVVWPIFGQEILNGDVGGGFHGIQITSGLFQLWRASGYTNEFQLYVTAIGALVMAGLMLFAGWFHYHKAAPKLEWFQNVESMLNHHLAGLLGLGSLSWAGHQIHVSLPVNKLLDAIDAGEPLVLNGKTIASAADIPLPHEFLDVSLISQLFPGFEAGVKAFFTLNWSAYADFLTFKGGLNPVTGGLWLTDTAHHHLAIAVLFIVAGHMYRTNWGIGHSLKEILEAHKGPFTGQGHKGLYEILTTSWHAQLSINLAILGSISIIVAHHMYAMPPYPYLATDYPTMLSLFTHHIWIGGFLIVGAGAHAAIFMVRDYDPAKNVDNLLDRVLRHRDAIISHLNWVCIWLGFHSFGLYIHNDTMRALGRPQDMFSDSAIQLQPIFAQWIQNIHALAPGNTAPNALASVSQVFGGDVVAVGGKVAAAPIVLGTADFMVHHIHAFTIHVTALILLKGVLYARSSRLVPDKANLGFRFPCDGPGRGGTCQVSGWDHVFLGLFWMYNSLSIVIFHYSWKMQSDVWGSVLPDGSVAHIANGNFAQSALTINGWLRDFLWAQASQVITSYGSSTSAYGLLFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPAIQPRALSIIQGRAVGVAHYLLGGIVTTWSFFLARIIAVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: UBA1B_ARATH
Sequence: MAKEGEERKKEKKEKKERKERKRREAEELAVREKKISKKHKSKSKEEEKPEKSKKKSKKYEEVEEEEKSPSPSPSPKKSKESKKKHKRSSDESEEIVDSKPVTVPIVTIESDSDFEFDKEDIKNLLESYSKEELINLIYKTAEKGSKLISAVFESADRDSSQRNIFVRGLGWDTTHENLKAAFEVYGEITECSVVMDKDTGRAKGFGFVLFKTRKGARAALKNPEKRMYNRTVSCLPARPFNSGKPREQQQPVESVKIDLSHTGNQSEMALPGIDLGHGLDKGHQQQQNMSMYAGQNMPFYGHSQPPPGFNPMYGAMMGNPMVAGLQNYRMFGSGMMNQGPMMPPNHMGMVGQYVGDGNVNGVGAGAGAGAGFDGERAWYLR
What is the function of this protein?
Acts as component of a complex regulating the turnover of mRNAs in the nucleus.  Binds with high affinity to RNA molecules that contain U-rich sequences in 3'-UTRs.  May function in complex with UBP1 and contribute to the stabilization of mRNAs in the nucleus (By similarity).
What are the official names of this protein?
UBP1-associated proteins 1B.
What are the subcellular locations of this protein?
Nucleus.
Protein: T2P7_PSEAI
Sequence: MALDLVDYEQKARDAVKAFWGNREAARQKQIESGKADQGERAGVTGGKNMDGFLALVLDVIKANGLAHAEIHQNRAMLTLPGYFRPTKLWDLLVIYKGELIAAIELKSHVGPSFSNNFNNRTEEAIGTAHDLWTAYREEAFGKQPRPFVGWLMMVEDAPESRRPVRDSSPHFPVFEEFKGASYLTRYDLLCQRLVQEQLYTTAAVIAAERSAVDTGNFTELSSMTSLKTFVSALAGHIAAEAARLG
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-CTCGAG-3' and cleaves after C-1.
What are the official names of this protein?
Type II restriction enzyme PaeR7I, R.PaeR7I, Endonuclease PaeR7I, Type-2 restriction enzyme PaeR7I.
What is the protein family that this protein belongs to?
Belongs to the XhoI type II restriction endonuclease family.
Protein: FOLD_PARMW
Sequence: MALRLDGKALAATVERRLTSVVDAHSKTVGQPPGLAVLRVGDDPASAVYVANKEKACARVGIASYGAHLAADTPADQVLSTIQSLNADPRVDGILLQLPLPKGLDERPLLEAIDPEKDADGLHTLNLGRLLKGEPGPRSCTPAGVMALLRSNGIDPAGQRAVVIGRSILVGQPMALMLQAANATVTVAHSRTADLAAHTREADIVVVAAGRPGMVGAEHVRPGAAVVDVGIHRKPEGGLCGDVVAEEVEPIAAALSPVPGGVGPMTVTMLLVNTVVAWCRRHGIDHELDDLIG
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: GLPK_CLOBH
Sequence: MEKYIMSLDQGTTSSRCIIFNKKGEIVSVAQKEFTQIYPKAGWVEHDPLEIWGKQAGVAGEALNIARISPEQIAGIGITNQRETTVVWNKRTGMPVYNAIVWQCRRTAGYCDELREKGIDKTIKEKTGLMLDAYFSATKIKWILDNVEGARELAEKGDLLFGNIDTWLIWNMTKGKIHVTDYTNASRTMLFNIHELKWDEELLEILDIPKSMLPEVKPSSCVYGETDEILFGVSIPIAGDAGDQQAALFGQTCFNAGMAKNTYGTGCFLLMNTGEKAVDSKNGLLTTIAVGIDGKVEYALEGSIFIGGAVIQWLRDELRMVKTAQETEKYATEVEDNNGVYLVPAFVGIGAPYWDSYARGTILGLTRGAKKEHIIRAALESMAYQTHDVLKAMEEDSGIELKALKVDGGACQNNFLMQFQSDILGVEVDRPEVVETTALGAAYLAGLAVGYWKDRNEISQNWAISRSFAPAMEDEKKEKLIKGWHKAVTKAMDWEERE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: GCH1_STRP3
Sequence: MKRERLMSINKEKAEAAIYQFLEAIGENPNREGLLDTPKRVAKMYAEMFLGLGKDPKEEFTAVFKEHHEDVVIVKDISFYSVCEHHLVPFYGKAHIAYLPSDGRVTGLSKLARAVEVASKRPQLQERLTSQIADALVEALNPKGTLVMVEAEHMCMTMRGIKKPGSKTITTTARGLYKESRAERQEVISLMTKD
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: MATK_MAIZE
Sequence: MEKFEGYSEKQKSRQHYFVYPLLFQEYIYAFAHDYGLNGSEPVEIFGCNNKKFSSLLVNRLIIRMYQQNFLINSVNYPNQDRLLDHRNYFYSEFYSQILSEGFAIVVEIPLSLGQLSCPEEKEIPNFQNLQSIHSIFPFLEDKFLHLHYLSHIKIPYPIHLEILVQLLEYRSQDVPSLHLLRFFLYYYSNWNSFITSMKSIFLLKKENKRLFRFLYNSYVSEYEFFLLFLHKQSSCLRLTSSGTFLERIIFSGKMEHFGVMYPGFFRKTIWFFMDPLMHYVRYQGKAILASKGTLLLKKKWKSYLVNFSQYFFSFWTQPQRIRLNQLTNSCFDFLGYLSSVPINTLLVRNQMLENSFLIDTRMKKFDTTVLATPLVGSLSKAQFCTGSGHPISKPVWTDLSDWDILDRFGRICRNIFHYYSGSSKKQTLYRLKYILRLSCARTLARKHKSTVRTFMQRLGSVFLEEFFTEEEQVFSLMFTKTIHFSFHGSHSECIWYLDIIRINDLVNPLTLN
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KATG_PARXL
Sequence: MSSEAKCPFNHAAGGGTTNRDWWPKQLRLDLLSQHSGKSNPLDGGFNYAEAFRSLDLAAVKKDLAALMTDSQDWWPADFGHYGPLFIRMAWHSAGTYRIGDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWADLLILTGNVALETMGFKTFGFAGGREDTWEPDLDVYWGNEKTWLGGDVRYGKGAAGDNDDGGVIVADEEKHGEEVSRDNSGRNLENPLGAVQMGLIYVNPEGPDGNPDPLAAAHDIRETFARMAMNDEETVALIAGGHTFGKTHGAGPADNVGPEPEAADLENQGLGWKNSFGTGKGADTITSGLEVTWTTTPTKWGNGFFENLFKYEWELTKSPAGAHQWVARDAGETIPHAHDPSKKLRPTMLTTDLSLRFDPVYEKISRRFLENPDQLADAFARAWFKLTHRDMGPRARYLGPEVPAEELNWQDPIPALDHPLVNEQDIASLKQKILASGLSVSQLVSTAWASASTFRGSDKRGGANGARIRLAPQKDWPVNQPEQLAKVLKVLEGIQSEFNGVQSGGKKISLADLIVLGGAAAIEQAAKSAGQQVSVPFSPGRMDASQEQTDVQSVAALEPLADGFRNYLKGKYRAPAEALLIDKAQLLTLTAPEMTVLLGGLRALNVHAGQDSHGVFTHRPQTLSNDFFRNLLDMGTEWKPLSPARDVFEGRDRKTGELKWTGTRVDLVFGSHAQLRALCEVYASEDAQEKFVRDFVAAWAKVMDLDRFEIA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: RS11_OLEA2
Sequence: MARPKRVGKKKEKKSIPVGVAHIQATFNNTIITFTDTRGNTVSWASAGQSGFKGSRKSTPFAAQIAADQAARRAQENGMRTVGIFVKGPGSGRESAMRAINAAGFKVAFIRDITPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: MAP21_ARTGP
Sequence: MGSKSPDGHRQGPNAESPSSSVAATTNPPKPAAASGLVQGMLDGDDEDEDGDDDGDNQRIGADLKSGVLPNNDGKKRKRKSNKKKKKKTSKGQQTTPPRVSLPSIFHDQRYPEGEIVEYAARNDNLQRTTAEELRHQAAIHNMDDEFLTDYRQAAEVHRQVRQYVQSIAKPGILMSELAEEIETGVRALTGHQGIETGDALKAGLAFPTGLCLNNVAAHWTPNPGAKEVILKHDDVLKIDFGVHVNGRIVDSAFTVASNPVYDNLLTAVKAATNTGLKEAGIDARIDHISGEIQEVMESYEVEINGKAIPVKALRSLTGHNILRYKIHGEKQVPFVKSKTTQRMEEGDVFAIETFGSTGKGYTRDEVGVYGYGLNEHASTAGLHHASAKSLLKTIRENFGTLVFSRRYLEHMGVKNYHLGMRSLISNDIVECYAPLVDVPGSYVAQFEHTVLLRPNCKEIISRGDDY
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase 2-1, MAP 2-1, MetAP 2-1, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHO1_CAEEL
Sequence: MVSAISIVAIFALEGFVTTYSDGTKDLVFVQTLWRHGDRSPTKTFKTDPFQEDAWQFGGGGWGQLSPAGMKQHLNLGKMLRNRYVTNYNFLPNKYNAKQIYVRSTDVNRTIISAMSNLLGQYGQNDNSSTPGLDYPDVDGWPAGYVPIAVHTVDDDTDHLGNMESTCPFKDQVWELAKTSDEVKSFVNSADVQAVLGNLTNYCGQPVDIDNLWIITNALYIEQIYYNATLRTKNNWFTDAFYAKADAINDQVQLFQNGIFKTVPNIVNGHDVGVLTRKVRGGPILNDMVMHINLKLMCQGQTTPNCTWINNLKNYIYSAHDTTIYAFFSALLIEEYAVKPSGGYPLYSAAVLLELYIDSVDKKPYFKMVYHEQDGSGFKDVTMGIQGCPQNSSYCDLDILRNFANTIKPDQPIDQWCLTDLNKSSSFATVSMLFIAAILAINNNFLGLF
What is the function of this protein?
Acid phosphatase required for normal growth and development.  Specifically required for normal gut differentiation.
What are the official names of this protein?
Intestinal acid phosphatase.
What is the protein family that this protein belongs to?
Belongs to the histidine acid phosphatase family.
What are the subcellular locations of this protein?
Membrane; Single- pass membrane protein. Membrane; Lipid-anchor, GPI-anchor.
Protein: FMO1_CANLF
Sequence: MAKRVAIVGAGVSGLASIKCCLEEGLEPTCFERSDDLGGLWRFTEHVEEGRASLYKSVVSNSCKEMSCYSDFPFPEDYPNYVPNSQFLEYLKMYANRFSLLKCIRFKTKVCKVTKCPDFTVTGQWEVVTQHEGKQESAIFDAVMVCTGFLTNPHLPLDCFPGINTFKGQYFHSRQYKHPDIFKDKRVLVIGMGNSGTDIAVETSRLAKKVFLSTTGGAWVMSRVFDSGYPWDMVFMTRFQNMFRNSLPTPIVTWLMARKMNSWFNHANYGLVPEDRTQLREPVLNDELPGCIITGKVLIKPSIKEVKENSVVFNNTPKEEPIDIIVFATGYTFAFPFLDETVVKVENGQASLYKYIFPVHLPKPTLAVIGLIKPLGSMIPTGETQARWAVRVLKGINKLPPQSAMTEEVNARKENKPSGFGLCYCKALQSDYITYIDELLTNINAKPNLFSLLLTDPRLALTIFFGPCTPYQFRLTGPGKWKGARNAILTQWDRTFKVTKTRIVQESPTPFASLLKLLSLLALLMAIFLIFL
What is the function of this protein?
Broad spectrum monooxygenase that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including xenobiotics (By similarity).  Catalyzes the S-oxygenation of hypotaurine to produce taurine, an organic osmolyte involved in cell volume regulation as well as a variety of cytoprotective and developmental processes (By similarity).  In vitro, catalyzes the N-oxygenation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine or L-carnitine (By similarity).
What are the official names of this protein?
Flavin-containing monooxygenase 1, Dimethylaniline monooxygenase [N-oxide-forming] 1, Dimethylaniline oxidase 1, Hepatic flavin-containing monooxygenase 1, FMO 1, Trimethylamine monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the FMO family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: SPF27_DICDI
Sequence: MNIIIEGAENIDSLPYVDDSVNENEQELINKLISDEMSTFTPPDYLAQLPSFIDIDYNNFQFLENDFKRMEKEEKMKEFDIGRYKVEPTTTMIKQQLNEKQWNDSLNNARSQLEHQDIRKINLELLQRYGGNSWKLYLSDLEILQKTLKKQLDQKKQQIEEINIQRKLSQEQTFEKIQQHDKKFLELVYKNTEIESACKSIELEIEQLKLKQQLQQQQENGDLNNK
What is the function of this protein?
Required for pre-mRNA splicing as component of the activated spliceosome.
What are the official names of this protein?
Pre-mRNA-splicing factor spf27.
What is the protein family that this protein belongs to?
Belongs to the SPF27 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: C102A_SSV1
Sequence: MNLIDIILFYGFQFNDYWTTVLGLRVGAEEKNPIAGLFISSPYRLALFKFGLITIGMFILIYVVRFKTWTEIVLTVTDVVECLVTLNNTLTIRRYKRRGVRG
What are the official names of this protein?
Uncharacterized protein C-102a.
Protein: PIN4_MOUSE
Sequence: MPPKGKSGSGKGGKGGAASGSDSADKKSQGPKGGGNAVKVRHILCEKHGKIMEAMEKLKSGMRFSEVATQYSEDKARQGGDLGWMTRGSMVGPFQEAAFALPVSGMDKPVFTDPPVKTKFGYHIIMVEGRK
What is the function of this protein?
Involved as a ribosomal RNA processing factor in ribosome biogenesis.  Binds to tightly bent AT-rich stretches of double-stranded DNA (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4, Parvulin-14, Par14, Peptidyl-prolyl cis-trans isomerase Pin4, PPIase Pin4, Rotamase Pin4.
What is the protein family that this protein belongs to?
Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Note=Colocalizes in the nucleolus during interphase and on the spindle apparatus during mitosis with NPM1.
Protein: PUR9_CLOK1
Sequence: MINRALISVYNKEGLLELAQFLKNKGVELISTGGTYKYLEQNDIQVTEVSKITGFDEILDGRVKTLHPVIHSGILAKRDNKEHMDTIAKKDILPIDMVVVNLYPFFDKVDDNITFEEKVEFIDIGGPTMIRAAAKNFKDVIVVTDVGDYSKLIEEIDSKGDVPYDFRKKLAGKVFNLMSAYDGAISNFLLEEDYPEYLSLSYKKMDNLRYGENPHQSAAYYTATAGTAPMKDFTQLNGKQLSYNNIKDMDIAWKVVNEFEEICCVAVKHNTPCGVALGKDLYEAYVKTYECDPTSIFGGIIAVNRKLDVKTAEEISKIFVEIVIAPDFDEEALKVLMEKKNLRIIKCSVKPTNSMEIAKVDGGILVQSADDKLVENMEVVTDKKPSKEEINNLIFGMKVCKYVKSNAIVVVKDFMAKGIGGGQVNRIWPTCHALDRAGDGVVLASDAFFPFNDVVCEAAKYGIKAIIQPGGSVRDKDSIEECNKNGISMVFTGVRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: ASL6_SARSH
Sequence: MTVKILVSGAGVAGTALVNFLCRSKHEYDITVVERAPALRAAGSQLDLKSFGAPLMRKLGLIEKVREKSIHETAFTFVDSKGREWARFPVNEAGKGYEGITSEFEIMRADLVAVLYEASKEVSANPFMKGPQKLRYVFGKHGVHFTQGNSKVNVVFSDGSSDDYDLVVGADGQYSMTRRLLWEPEKGSGDTTLKYTGVTAGFFQMPKSEDEADSTLFKNCLQAGPRGLCLRCAHKDFTQAMLGIPTTDEHKQVFKKPLEQQKQMWEESVGSFKWQGQRVLAELRKSDDFYMTPVAQVKVDRWSKGRVVLVGDAGYCPSVMTGRGTTVSLVGAYVLAGELAKHGDNIDAALESYEKVLRPFITTAQEIPSMGMGMFQSKFGVGVFYVLLAIISKLKIDRLLQALMKEEKETWELPEYPELEFEA
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of xenovulene A, an unusual meroterpenoid that has potent inhibitory effects on the human gamma-aminobutyrate A (GABAA) benzodiazepine receptor (PubMed:29773797).  The first step of xenovulene A biosynthesis is the biosynthesis of 3-methylorcinaldehyde performed by the non-reducing polyketide synthase aspks1 (PubMed:17912413, PubMed:29773797, PubMed:20552126).  The salicylate hydroxylase asL1 then catalyzes the oxidative dearomatization of 3-methylorcinaldehyde to yield a dearomatized hydroxycyclohexadione (PubMed:29773797).  The 2-oxoglutarate-dependent dioxygenase asL3 further catalyzes the oxidative ring expansion to provide the first tropolone metabolite (PubMed:29773797).  The cytochrome P450 monooxygenase asR2 allows the synthesis of tropolone hemiacetal (PubMed:29773797).  In parallel, a previously unrecognised class of terpene cyclase, asR6, produces alpha-humulene from farnesylpyrophosphate (FPP) (PubMed:29773797).  The putative Diels-Alderase asR5 probably catalyzes the formation of the tropolone-humulene skeleton by linking humulene and the polyketide moiety (PubMed:29773797).  Oxidative-ring contractions catalyzed by asL4 and asL6 then processively remove carbon atoms from the polyketide to yield xenovulene A (PubMed:29773797).
What are the official names of this protein?
FAD-dependent monooxygenase asL6, Xenovulene A biosynthesis cluster protein L6.
What is the protein family that this protein belongs to?
Belongs to the aromatic-ring hydroxylase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: HHEX_XENLA
Sequence: MQYQHPSSSALGLSVPLFAPTPLQHPTPFYIDDILGRNSASNGTPALPTPTLPSPNSSFTSLVATYRTPIYEPTPIHPAFTHPGAALAASYGASTYASPLYPFSRPVSDYTHALIRHDSLGKPLLWSPFIQRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQENPQGNKKDETESLENICEESQERCLSAEQKSRESSLDDPTSSPTSQGNLDSEVSDDSDQEVDIEGDKGYYNCAH
What is the function of this protein?
Recognizes the DNA sequence 5'-ATTAA-3'.  Transcriptional repressor.  Regulates the differentiation of both endothelial and blood cells (By similarity).  Probably plays a role in the proliferation of vascular endothelial cells during blood vessel development.  Establishes anterior identity at two levels; acts early to enhance canonical wnt-signaling by repressing expression of tle4, and acts later to inhibit nodal-signaling by directly targeting nodal/nr1 and nodal2/nr2.  May play a role in liver development.  Induces heart development.
What are the official names of this protein?
Hematopoietically-expressed homeobox protein hhex, Homeobox protein hex, XHex, Hhex-A protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARR2_ARATH
Sequence: MVNPGHGRGPDSGTAAGGSNSDPFPANLRVLVVDDDPTCLMILERMLMTCLYRVTKCNRAESALSLLRKNKNGFDIVISDVHMPDMDGFKLLEHVGLEMDLPVIMMSADDSKSVVLKGVTHGAVDYLIKPVRIEALKNIWQHVVRKKRNEWNVSEHSGGSIEDTGGDRDRQQQHREDADNNSSSVNEGNGRSSRKRKEEEVDDQGDDKEDSSSLKKPRVVWSVELHQQFVAAVNQLGVDKAVPKKILEMMNVPGLTRENVASHLQKYRIYLRRLGGVSQHQGNMNHSFMTGQDQSFGPLSSLNGFDLQSLAVTGQLPPQSLAQLQAAGLGRPTLAKPGMSVSPLVDQRSIFNFENPKIRFGDGHGQTMNNGNLLHGVPTGSHMRLRPGQNVQSSGMMLPVADQLPRGGPSMLPSLGQQPILSSSVSRRSDLTGALAVRNSIPETNSRVLPTTHSVFNNFPADLPRSSFPLASAPGISVPVSVSYQEEVNSSDAKGGSSAATAGFGNPSYDIFNDFPQHQQHNKNISNKLNDWDLRNMGLVFSSNQDAATATATAAFSTSEAYSSSSTQRKRRETDATVVGEHGQNLQSPSRNLYHLNHVFMDGGSVRVKSERVAETVTCPPANTLFHEQYNQEDLMSAFLKQEGIPSVDNEFEFDGYSIDNIQV
What is the function of this protein?
Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'.  Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system.  Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes.  Could directly activate some type-A response regulators in response to cytokinins.  Involved in the expression of nuclear genes for components of mitochondrial complex I.  Promotes cytokinin-mediated leaf longevity.  Involved in the ethylene signaling pathway in an ETR1-dependent manner and in the cytokinin signaling pathway.
What are the official names of this protein?
Two-component response regulator ARR2, Receiver-like protein 5.
What is the protein family that this protein belongs to?
Belongs to the ARR family. Type-B subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RBL_NYMOD
Sequence: SVGFKAGVKDYRLTYYTPEYETLATDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTSEEMIKRAVCARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQRNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGERDVTLGFVDLLRDDFIEKDRSRGIYFTQDWVSMPGVLPVASGGIHVWHMPALTEIFGDDSVLQFG
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site (By similarity).
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SUCC_BACCZ
Sequence: MNIHEYQGKAVLRSYGVSVPNGKVAFTVEEAVEAAKELGTDVCVVKAQIHAGGRGKAGGVKVAKNLDEVRTYAESILGTTLVTHQTGPEGKEVKRLLIEEGCDIKKEYYVGLVLDRATSQVVLMASEEGGTEIEEVAEKTPEKIFKEYIDPAVGLQGFQARRIAFNINIPKELVGQAVKFMMGLYRAFIEKDCSIAEINPLVTTGDGKVMALDAKLNFDSNALYRHKDILELRDLDEEDAKEIEASKYDLNYIPLDGNIGCMVNGAGLAMATMDIIKHYHGDPANFLDVGGGATAEKVTEAFKIILSDKNVKGIFVNIFGGIMKCDVIAEGVIEATKQVGLELPLVVRLEGTNVELGKKILNESGLNIVAAESMADGAQKIVSLVG
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.