PharMolix/UniProtQA huggingface dataset:
Protein: ISPE_PEDPA
Sequence: MEITEKAPAKLNLFLDTPFNHPDGLPEWNMIMTSVDLADYVKIESIPGKMGIKVRTNTGFLPNDSRNLAYQAARILQEKYHVRAKVIIEIRKHIPVAAGLGGGSSDAAAVLRGLNKLWNLELSLEVLAKIGLEIDSDVPFCVYSRTAHVLGKGEKVIPLKKLPPMWVVIAKPKLSVSTPYILSKIEHKELQHSNIESILDAIEREDYTDICRYMGNVLEQVTGKEHPEVLKIKNRIKQYGADAAQMSGTGPTVFGVASKSSRAKHIVNSLKGFCHEVYLVRIL
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: RL14_PARUW
Sequence: MIQQESELEVADNSGAKRVKCFKVLGGSKRRYAHVGDIVVASVQDAHPEGSVKKGDVVKVVIIRTKSYIKRKDGTKIRFDTNSCVLIDDKKNPKGTRIFGPVAREVRDRDFLKISSLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RL30_LIGS1
Sequence: MDKLKVTLIRSVIGRPQNQRDIVKGLGLGRVNSSVVVPDNAAMRGAIRKINHLVDVELAK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: HYDMA_HYDVU
Sequence: MRTVVFFILVSIFLVALKPTGTQAQIVDCWETWSRCTKWSQGGTGTLWKSCNDRCKELGRKRGQCEEKPSRCPLSKKAWTCICY
What is the function of this protein?
Cationic antimicrobial peptide potently active against Gram-positive and Gram-negative bacteria including multi-resistant human pathogenic strains.  Is not active against the Gram-positive Coccus species, Gram-negative non-fermentation species and against the fungus C. albicans.  It leads to aggregation of bacteria as an initial step of its bactericidal mechanism.  Aggregated cells are connected via electron-dense contacts and adopt a thorn apple-like morphology.  Hydramycin contains a belt of positively charged residues that separate two hydrophobic areas.  This structure may explain the observed aggregation of bacteria, since each of these areas can immerse into the outer leaflets of the membranes of two individual bacteria.  Is able to permeabilize membranes of viable bacteria at low and neutral pH values, but no pore-forming activity is not detected.
What are the official names of this protein?
Hydramacin-1, Hm-1.
What is the protein family that this protein belongs to?
Belongs to the macin family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: RL3_ALKMQ
Sequence: MKGLMGRKVGMTQIFNEDGIVTPVTVIEVAENVVTQIKSDETDGYNSVQVGYGEKKIKNTIKPLQGHFEKAGTTPKRTMKEFRVDSTEGFTAGQELKADLFQAGDKVDVTGISKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGASAYPGRVFKGKNLPGHMGNVQVTAQNLEIVRVDLEKNLLLIKGAVPGPKKGVLVIQTTVKQGK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: SYA_BACFN
Sequence: MLTAKETRDSFKNFFESKGHQIVPSAPMVIKDDPTLMFTNAGMNQFKDIILGNHPAKYHRVADSQKCLRVSGKHNDLEEVGHDTYHHTMFEMLGNWSFGDYFKKEAISWAWEYLVDVLKLNPEHLYATVFEGSPEEGLERDNEAASYWEQYLPKDHIINGNKHDNFWEMGDTGPCGPCSEIHIDLRPAEERAKISGRDLVNHDHPQVIEIWNLVFMQYNRKADSTLEPLPAKVIDTGMGFERLCMALQGKTSNYDTDVFQPLIKAIAQMAGTEYGKNEQNDIAMRVIADHIRTIAFSITDGQLPSNAKAGYVIRRILRRAVRYGYTFLGQKQAFMYKLLPVLIDSMGDAYPELIAQKELIEKVIKEEEESFLRTLETGIRLLDKTMADTKANGKTEISGKDAFTLYDTFGFPLDLTELILRENGMTVNVEEFDAEMQQQKQRARNAAAIETGDWIILKEGTTEFVGYDYTEYETSILRYRQVKQKNQTLYQIVLDYTPFYAESGGQVGDTGVLVNEFETIEVIDTKKENNLPIHITKKLPEHPEAPMMACVDTDKRAACAANHSATHLLDEALREVLGEHVEQKGSLVTPDSLRFDFSHFQKVTDEELRKVEHLVNAKIRANVPLQEHRNIPIEEAKELGAIALFGEKYGDHVRVIQFGSSIEFCGGTHVAATGNIGMVKIISESSVAAGVRRIEAYTGARVEEMLDTIQDTLSDLKALFNNTPDLGVAIRKYIDENAGLKKQVEDFMKEKEAAVKERLLKNVQEINGIKVIKFCLPMPAEVVKNIAFQLRGEITENLFFVAGTVDANKPMLTVMISDNLVAGGLKAGNLVKEAAKLIQGGGGGQPHFATAGGKNPDGLNAAVEKVLELAGI
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_SYNE7
Sequence: MAPQLRIFVPPHPLIRHWLGIARDRQTPTPLFRTAIAELGRWLAYEAVREWLPTIPAAVQTPLAETPAEFVDFSQPLAIVPILRAGLGLVESVQQVLPTARIFHVGLKRDEVSLEPRCYLNHLPEQLEVNSRVLVLDPMLATGGSLLYTLDLLRDRGVSAEQVRVLSIVAAPPALQKLSQAYPALTIYSAIIDEQLNDKGFIVPGLGDAGDRLFGTP
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: OTCA_PYRFU
Sequence: MVVSLAGRDLLCLQDYTAEEIWTILETAKMFKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYATVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDQAENRLHAQKAVLALVMGGIKF
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis.
What are the official names of this protein?
Ornithine carbamoyltransferase, anabolic, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSP4_ROTHM
Sequence: MDKLADLNYTLSVITSMNDTLHSIIEDPGMAYFTYIASVLTVLFTLHKASIPTMKIALKTSKCSYKVLKYCIVTIINTFLKLAGYKEQVTTKDEIEQQMDRIVKEMRRQLEMIDKLTTREIEQVELLKRIHDNLITRTVDVIDMSKEFNQKNIKTLDEWESGKNPYEPSEVTASM
What is the function of this protein?
The secreted form acts as an enterotoxin that causes phospholipase C-dependent elevation of the intracellular calcium concentration in host intestinal mucosa cells.  Increased concentration of intracellular calcium disrupts the cytoskeleton and the tight junctions, raising the paracellular permeability.  Potentiates chloride ion secretion through a calcium ion-dependent signaling pathway, inducing age-dependent diarrhea.  To perform this enterotoxigenic role in vivo, NSP4 is released from infected enterocytes in a soluble form capable of diffusing within the intestinal lumen and interacting with host plasma membrane receptors on neighboring epithelial cells such as integrins ITGA1/ITGB1 and ITGA2/ITGB1.
What are the official names of this protein?
Non-structural glycoprotein 4, NSP4, NCVP5, NS28.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP4 family.
What are the subcellular locations of this protein?
Host rough endoplasmic reticulum membrane; Single-pass type III membrane protein. Host membrane, host caveola; Single-pass type III membrane protein. Secreted. Note=NSP4 localizes also in vesicular structures which contain autophagosomal markers and associate with viroplasms in virus- infected cells. Additionally, a soluble form of glycosylated NSP4 is secreted despite retention of its transmembrane domain.
Protein: ARFB_ARATH
Sequence: MASSEVSMKGNRGGDNFSSSGFSDPKETRNVSVAGEGQKSNSTRSAAAERALDPEAALYRELWHACAGPLVTVPRQDDRVFYFPQGHIEQVEASTNQAAEQQMPLYDLPSKLLCRVINVDLKAEADTDEVYAQITLLPEANQDENAIEKEAPLPPPPRFQVHSFCKTLTASDTSTHGGFSVLRRHADECLPPLDMSRQPPTQELVAKDLHANEWRFRHIFRGQPRRHLLQSGWSVFVSSKRLVAGDAFIFLRGENGELRVGVRRAMRQQGNVPSSVISSHSMHLGVLATAWHAISTGTMFTVYYKPRTSPSEFIVPFDQYMESVKNNYSIGMRFKMRFEGEEAPEQRFTGTIVGIEESDPTRWPKSKWRSLKVRWDETSSIPRPDRVSPWKVEPALAPPALSPVPMPRPKRPRSNIAPSSPDSSMLTREGTTKANMDPLPASGLSRVLQGQEYSTLRTKHTESVECDAPENSVVWQSSADDDKVDVVSGSRRYGSENWMSSARHEPTYTDLLSGFGTNIDPSHGQRIPFYDHSSSPSMPAKRILSDSEGKFDYLANQWQMIHSGLSLKLHESPKVPAATDASLQGRCNVKYSEYPVLNGLSTENAGGNWPIRPRALNYYEEVVNAQAQAQAREQVTKQPFTIQEETAKSREGNCRLFGIPLTNNMNGTDSTMSQRNNLNDAAGLTQIASPKVQDLSDQSKGSKSTNDHREQGRPFQTNNPHPKDAQTKTNSSRSCTKVHKQGIALGRSVDLSKFQNYEELVAELDRLFEFNGELMAPKKDWLIVYTDEENDMMLVGDDPWQEFCCMVRKIFIYTKEEVRKMNPGTLSCRSEEEAVVGEGSDAKDAKSASNPSLSSAGNS
What is the function of this protein?
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).  Could act as transcriptional activator or repressor.  Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression.  Promotes flowering, stamen development, floral organ abscission and fruit dehiscence.  Functions independently of ethylene and cytokinin response pathways.  May act as a repressor of cell division and organ growth.
What are the official names of this protein?
Auxin response factor 2, ARF1-binding protein, ARF1-BP, Protein MEGAINTEGUMENTA.
What is the protein family that this protein belongs to?
Belongs to the ARF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CHEB2_ANADE
Sequence: MSLAGGDRPIRVLVADDSELFRELLARVVAAEPGFEVAAVAADGDAAAAMARALRPDVVTMDLHMPDADGYSGIARIMAETPTPILVLTANPTEAAGFRALSLGALDILEKPSATADLGEYGRLIRSRLRLLAGVKVIRHLRGLRERRDAAPARAARVEVVVIGASLGGPRALAAVLRGLPPDFPAPIAVVQHIADGFTAGLAGWLAQESRLDVREARHGDPLRAGRVLIAPSGRHLVLGEGVARLSDAPPVDTFRPSVTPLFTSAARQYGRRCCGVLLTGMGRDGAEGLRVIKDAGGPTLAQDEATSAVFGMARAAVELGAVDRVLPVDEIPRALRELTR
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_SHEB2
Sequence: MQNQRIRIRLKGFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERYTILISPHVNKDARDQYELRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: ICP27_GAHVM
Sequence: MSVDAFSRESDDMMSLLDYDFIEGSSSDENAEVTEMETSAKTANNKNEVLFAPPCTQELLTERPSPDSKNSQGDDDSNSIYGNVIRDAQHSASRYATRCLDNAIPRKRLRLANLTVDSACISQTKRPHGTGNRKQYHRRNFPMSPTSQEKIHLRLHNRLGSRSEKQQRSLNYDRRLQEGHHRRRFYSERRIYDQNHSHHRTHDIRVPLEKYRVSRQHDLPVHEELNEILQREKHRLASISNECDFRVSSKNRWAAVLTFSSNAESTLCGPQITWEYLLHAGPELRNTFEIRPRISLQASAAREAVLRGESFIAALGSAEETLSWLKLHAVLKLRLVNHDPIFKTAGAVLDNLRLKLAPIMMCKYGTEKRSMGDMLRRSAPEDINDSLTLCLILLSRIRRVMHRTSGSKYSYMIDPRGCMIDYVPGECMTNILRYVDAHTRRCSDPACNLYISCTLMPIYIHGRYFYCNTLFGM
What is the function of this protein?
Multifunctional regulator of the expression of viral genes that mediates nuclear export of viral intronless mRNAs.  This immediate early (EI) protein promotes the nuclear export of viral intronless mRNAs by interacting with mRNAs and host NXF1/TAP (By similarity).
What are the official names of this protein?
mRNA export factor ICP27 homolog, Transcriptional regulator IE63 homolog.
What is the protein family that this protein belongs to?
Belongs to the HHV-1 ICP27 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Shuttles between the nucleus and the cytoplasm.
Protein: GSHB_PROMA
Sequence: MKQLFILDPIELINPAKDSSAALMQAAHRASLDIWVCTPADLQAKGAKARVVAKTIVPEPWKSLGEAQNLSLNEFHCIWMRKDPPVDEAFLYATHLLEVAERAGVLVLNKPASLRAWNEKLGALRFSKLMAPTLVASRVNELKEFAKEQGEVVLKPLGGKGGQGVIRVADAALGLDALLELVTSQEQMPVMMQKFLPKVIEGDKRILLVNGEPLGAINRLPKCGDFRSNLALGGQAEATNLSKREKEICEELGPSLKSEGLFFVGIDVIGGMLSEINVTSPTGVREVEKLMNIPLADQVIERLLANFS
What are the official names of this protein?
Glutathione synthetase, GSH synthetase, GSH-S, GSHase, Glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic GSH synthase family.
Protein: NADE_CHLP8
Sequence: MEPQDLHLDYGLVESILIPFIRNEIRKFGFRSVVLGLSGGIDSAVVCELAARSLGADNVLALLMPYKTSSRESLEHAQLMVDRLGIRAETMPVTGVVDAFFETRPDASRLRRGNVMARSRMLCLYDVSARDGCLVLGTSNKTELMLGYGTMFGDMASAVNPIGDLYKTQLWGLARHLGVPSELIDKQPSADLWEGQSDEADLGFSYEEVDQLLYMMLEERMERDAILAEGIAPAFYDRVRQMVVRNQYKRMMPVIAKLSSRTPGIDFRYARDWQEMK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: FRDC_SALEP
Sequence: MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELIFGLFALKHGAESWMGFVGFLQNPVVVILNLITLAAALLHTKTWFELAPKAANIIVKDEKMGPEPIIKGLWVVTAVVTVVILYVALFW
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Fumarate reductase 15 kDa hydrophobic protein, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MDH_MORMI
Sequence: MKVAVLGAAGGIGQALALLLKTQLPAGSDLSLYDIAPVTPGVAVDLSHIPTDVTIAGFAGMDPTDALVGADVVLISAGVARKPGMDRSDLFNINAGIIKNLAGKCAEVCPNACIGIITNPVNTTVPIAAEVLKQAGVYDKRKLFGITTLDVIRSETFVSELKGISLADVEVPVIGGHSGVTILPLLSQVKGVEFTAEEIATLTPRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVRALQGEEGIVECTYVDGGSEHATFFAQPVLLGKNGVEEVLAYGELSEFETNARDAMLEELKANITLGEEFVAG
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: EIF3F_ANOGA
Sequence: MSTINLPLNLTVRVHPVVLFQIVDAYERRNADSERVIGTLLGSVDKGVVEVTNCFCLPHKEHTDQVEAELGYASDLYELNQRVNASENIVGWWATGQEVTNHSSVIHEYYARECTNPVHLTLDTSLTGARMGIKAYVCVSLGVPGGKSGCMFTPINVEVTSYEPEIVGLQLCMKTIGVQSNPSRPRTVSPMLDLAQVTDASDKLLALLSDVLAYVEDVLSEKQQPENTVGRALLDLIHSVPNMTGDQFAQMFNSNVKDLLMVVTLSQLIKTQLQLNEKLTSLTSFLN
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit F, eIF3f, Eukaryotic translation initiation factor 3 subunit 5.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit F family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_CORK4
Sequence: MIQQESRLRVADNTGAREILCIRVLGGSTRRFAGIGDVIVATVKEATPGGNVKAGDIVKAVIVRAKKETRRPDGSYIRFDENAAVLIRNDNEPRGTRIFGPVARELRDKKFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: SELA_DESBA
Sequence: MSSLFRHIPSVDRFLQDLEQDRALADLPRQMLKDLVAEFLDLCREEIRAGVVTDESALAFTTLAARAGAYVRTRSRPHFRRVVNATGVVIHTNLGRSILAEEAVLAVAEGCRHYSNLEMDLDTGQRGSRYSHVEKLLCRLTGAEAGLVVNNNAAAVLLVLDTLAKGREVVVSRGQLVEIGGSFRIPEVMKKSGAVLREVGATNRTHLRDYAEAIGPDTAMLMKVHTSNYRIIGFHKEVDLPDLVALGRERGLSTFEDLGSGNLFDFSPYGFMPEPTVQQVLRSGVDVVTFSGDKLLGGPQAGVIVGRREFIERIKKNQLNRALRIDKMTLAALEATLRLYLDPEQARRTVPTLAMITAAPKELHARAGRLRRRLSRDLAGLASVAVKPGFSRVGGGSFPEQDLSTTLVSVAPTGMDVDSLRQGLLAEDIPVVGRVEDGAFCLDPRTLMDAEFALVAGAMKAVLAR
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHOP1_DANRE
Sequence: MRDSVFNCCVSPPHPPGAAAAERRSRSPAPQNHSRFLMFFDFDETLVDECSDDSMVSAAPGGVLPGWLKDTYRPGRYNEYMQRVLAYLSEQGVTPAAIRATVEKLPPCPGIPALMHFLLSQPSRDFEVVCVSDANTVFIETWLQHMGFQPLFLRIFTNPAHFDDNGVLQLRPFHSHECLRCPANMCKAVVVRQYVAQRIRERGGRPYQKVLYMGDGANDFCPSLTLSPGDVAFPRRDFPMHKLIQEMGEAKPGEFKASVVPWKSGEDVVNTLRKILERT
What is the function of this protein?
Phosphatase that has a high activity toward phosphoethanolamine (PEA) and phosphocholine (PCho).  Involved in the generation of inorganic phosphate for bone mineralization.
What are the official names of this protein?
Probable phosphatase phospho1.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.
What are the subcellular locations of this protein?
Extracellular vesicle. Note=Localizes to special class of extracellular vesicles, named matrix vesicles (MVs), which are released by osteogenic cells.
Protein: RL36_DEIRA
Sequence: MKVRSSVKKMCDNCKVVRRHGRVLVICSNVKHKQRQG
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: CLPB_LISMF
Sequence: MDLQKFTQQVQQTIADAQNLAIASEHQEIDVAHVFKVLLTESDFAKRVYDVAEVDIDALQKTVEDALTKIPVVSGSGVNYGQAMSQALFQLMRDAEKEQKQLDDDFVSTEHLILAVMDQKSNPITMNLKKQHKSKKQIQEAILKIRGGKKVTSQNAEENYEALTKYGRDLVAEVRSGKLDPVIGRDAEIRNVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVRKDVPEGLKDKTIISLDIGSLIAGAKYRGEFEERLKAVLQEVKQSDGQILLFIDEIHTIVGAGKTDGAMDAGNMLKPMLARGELHCIGATTLDEYRQYIEKDAALERRFQKVLVPEPTVEDTVSILRGLKERFEIHHGVNIHDNALVAAASLSNRYITDRFLPDKAIDLVDEACATIRVEIDSMPSELDEVTRKVMQLEIEEAALKEEKDPASERRLEILQRELADYKEEANQMKSKWESEKNEISKIREVREQIDHLRHELEEAENNYDLNKAAELRHGKIPAVEKELLELEAENREKTAQEDRILQEEVTENEIAEIVGRWTGIPVTKLVEGEREKLLKLADELHQKVIGQDDAVQLVSDAVLRARAGIKDPKRPIGSFIFLGPTGVGKTELAKALAFNMFDSEDHMIRIDMSEYMEKHSVSRLVGAPPGYVGYEEGGQLTEAVRRNPYSIVLLDEIEKAHPDVFNILLQVLDDGRITDSQGRLIDFKNTVIIMTSNIGSNLLLERTEEGEISPELESDVMQILQSEFKPEFLNRVDDIILFKPLTLADIKGIVEKLVEELQIRLADQEITITISDNAKAFIAEEAYDPVYGARPLKRYIVRHVETPLAREIVSGKIMPHSSVEIDLADKEFTFKVTE
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FADB_ACIAD
Sequence: MIHAGNAITVQMLSDGIAEFRFDLQGESVNKFNRATIEDFQAAIEAVKNHPEVKGLIVTSAKSTFIVGADITEFGQNFAQGEKAIVEWALPVHDIFNSFEDLDIPKVAAINGMALGGGFEMCLVCDYRVMSDQAQVGLPEIKLGIFPGFGGTVRLSRLIGIDNAVEWIAMAAPKKPAAALKDGAVDAVVSADKLQEAAIDLVKQALAGRVDWKAKRQEKLNPVKLNPLEQMMAFNTAKGAVLAKANPAQYPAPKLMLDSLQAGASLGRDEALKVETEGFAKAAITPQAEALIGLFLNDQIIKKTSKKHEKGAHPVNQAAVLGAGIMGGGIAYQAASKGTPIIMKDIGNPQLALGMQEANGLLTKQVERKKLTPAKMGETLARIRPTLSYDEFKEVDIVIEAVTENPKIKEAVLADTEAKVRDNTIIASNTSTISITRLAKALKRPENFVGMHFFNPVHMMPLVEVIRGEQTSEEAVATTVVLAQKMGKTPIVVNDCPGFLVNRVLFPYFGAFDLLLKDGADFQQIDKVMEKFGWPMGPAYLMDVVGIDTGVHGAEVMAEGFPDRMKPDYKGSIQTMYEAKRLGQKNDVGFYKYELDKKGKKAKTVDSTAYEVIAPVVTSEKREFDAQEIIDRMMLALCNETVRCLEDNIVATPAEADMAMIMGIGFPPFRGGPCRYIDQTGVAEYVALCNKYAHLGKAYEAPQLLRDMAENNKKFYG
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: TSAD_MYCS2
Sequence: MIILAIESSCDETGVGIADLRDDGTVTLLADEVASSVDEHARFGGVVPEIASRAHLEALGPTMRRALDAAGIERPDVVAATIGPGLAGALLVGVAAAKAYAAGWGVPFYGVNHLGGHLAADVYDHGPLPESVGLLVSGGHTHLLHVRSLGEPIIELGSTVDDAAGEAYDKVARLLGLGYPGGRVLDELARTGDRDAIVFPRGMTGPRDDPYTFSFSGLKTAVARYVEAHPEASHADVAAGFQESVADVLTAKAVRAATDLGVSTLLIAGGVAANSRLRELAEERCAAAGLTLRVPRPRLCTDNGAMIASFAAHLIAAGAQPSPLDAASDPGLPVVKGQVA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_CLOBB
Sequence: MKNILDYTLEELTLWMKENNESSFRAKQIMSWIYKDVRNFSDMRNMPKSLIAKLEENFEIALPEIEEIYKSELDGTEKFLFKFSDGNLIESVLMRYKHGNSICISTQVGCRMGCKFCASTIDGRIRNLTTGEILAQILVVQNHIGERISNVVLMGSGEPLDNYENVMKFLDIVSAEYGLNIGQRHITLSTCGIVPKIYELADKELSITLAISLHAFSDEKRKEIMPIANKYSIDEILNACKYFVNKTKRRITFEYSLVKDVNDSKEDARALGKLLKGMLCHVNLIPVNEIKERTFKRSSKETIQDFANILSNLGIEVTVRREMGSDINAACGQLRRSYIKTQETRGE
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.