PharMolix/UniProtQA huggingface dataset:
Protein: CH60_PSELT
Sequence: MPKLLRFDEEARRSLEKGVNKVADAVRITLGPKGRNVVIEKSWGSPTITNDGVSIAKEIELEDKFENLGAQLVKEVASKTNDVAGDGTTTATVLAQSMIREGLKNVAAGSNPILLKRGIDKATEKAAKYIKDKAKKLSGREDIAHVAAISANSSEIGDLIAEAMDKVGEDGVITVEDSKTLETYVEFTEGMQFDRGYISPYFVTDAEKMEVELKEPFILITDKKLSAVKPLIPVLEKVAQTGKPILVIAEDVEGEALTTLVLNKLKGTLSACAVKAPGFGDRRKAMLQDIAILTGGTVISDELGINLEDVAIEDLGRADIVRVKKDDTIIIGGKGNPEEIKKRIAQIKSQIEQTTSEYEKETLQERMAKLAGGVAVIKVGAATETELKEKKHRIEDALSATRAAVEEGIVPGGGVTLIRSRKAVEDVLKELDGDEKVGAMIVYKALEAPIRQIAENAGYDGAVIIEKILASKEESYGFDALKGEYTDMFKAGIIDPAKVTRSALQNAASIAGMLLTTEVLVVEKPEEKKEAAPAMPPEY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGX_SALCH
Sequence: MTQLAIGEATPHGATYDGHGVNFTLFSAHAERVELCVFDSRGNERRYDLPGRRGDVWHGYLAGARPGLRYGYRVHGPWQPAQGHRFNPAKLLLDPYARRVEGELKDHPLLHGGHDEPDYRDNAAVAPKSVVISDHYDWEDDAAPRTPWGKTVIYEAHVKGLTYLHPELPQEIRGTYKALGHPVMVAYFKQLGITALELLPVAQFASEPRLQRMGLTNYWGYNPMAMFALHPAWASSPETALDEFRDAVKALHRAGIEVILDIVLNHSAELDLDGPTFSLRGIDNRSYYWIRDDGDYHNWTGCGNTLNLSHPGVVEYACECLRYWVETCHVDGFRFDLASVMGRTPTFRQDAPLFAAIKACPVLSTVKLIAEPWDIGEGGYQVGNFPPPFAEWNDHFRDAARRFWLPRNLTTGEFACRFAASSDVFKRNGRAPGASVNLLTAHDGFTLRDCVCFNQKHNEANGEENRDGTNSNYSDNHGKEGLGGPLDLMERRRDSIHALLATLLLSQGTPMLLAGDEHGHSQHGNNNAYCQDNALTWLDWQQANRGLTTFTAALIRLRQQIPALTGNSWWEEGDGNVRWLNKNAQPLSADEWQNGPKLMQILLSDRFLIAINATLEVTDIVLPEGEWRAVPPFAGEDNPVITAVWQGPAHGLCVFQRG
What is the function of this protein?
Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.
What are the official names of this protein?
Glycogen debranching enzyme, Limit dextrin alpha-1,6-maltotetraose-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: CHMP5_DICDI
Sequence: MKRFFGVSNNQPAPTLDEATKRIGGRMGQMDEKINGLNQELLAYDKQIKATRPGPAQNAIKQKAIRVLQQKKMYERQRDQMASTSFNMEQTKFATESMRDTITTVSAMKQGAKDMKTQLKHIKIEDVDDMQDEMQDLLDYNNEIQESLGRAYQTPDTLDESELEAELMSMGEELELEASMPSYLMTPSVPTTDPHQSSVDEYGLPIGQEASQQVV
What is the function of this protein?
Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and are delivered to lysosomes enabling degradation of membrane proteins (By similarity).
What are the official names of this protein?
Charged multivesicular body protein 5, Vacuolar protein-sorting-associated protein 60.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein.
Protein: PA2H4_BOTMT
Sequence: SLVELGKMILQETGKNPVTSYGAYGCNCGVLGRGKPKDATDRCCYVHKCCY
What is the function of this protein?
Snake venom phospholipase A2 homolog that lacks enzymatic activity (PubMed:31340737).  Shows cytotoxic activity (IC(50)=81. 2 ug/mL) against murine fibroblasts (PubMed:31340737).  Shows high myotoxic activity, neutrophile activation, slight cytotoxicity against tumor cell lines, and slight antiparasitic activity against promastigote forms of Leishmania amazonensis (By similarity).  A model of myotoxic mechanism has been proposed: an apo Lys49-PLA2 is activated by the entrance of a hydrophobic molecule (e. g.  fatty acid) at the hydrophobic channel of the protein leading to a reorientation of a monomer (By similarity).  This reorientation causes a transition between 'inactive' to 'active' states, causing alignment of C-terminal and membrane-docking sites (MDoS) side-by-side and putting the membrane-disruption sites (MDiS) in the same plane, exposed to solvent and in a symmetric position for both monomers (By similarity).  The MDoS region stabilizes the toxin on membrane by the interaction of charged residues with phospholipid head groups (By similarity).  Subsequently, the MDiS region destabilizes the membrane with penetration of hydrophobic residues (By similarity).  This insertion causes a disorganization of the membrane, allowing an uncontrolled influx of ions (i. e.  calcium and sodium), and eventually triggering irreversible intracellular alterations and cell death (By similarity).
What are the official names of this protein?
Basic phospholipase A2 homolog BmatTX-IV, svPLA2 homolog, Lys49 PLA2-like.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. K49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PSD_AROAE
Sequence: MSNNYPHPLLAREGWPFIAIALAVALVINGAAGFGWALPFWLLFIFVVQFFRDPPRPIPQGAKDVLSPADGRIVAIEPVRDPYLDRDSVKISVFMNVFNVHSNRSPVDGEVVARWYNAGRFVNAALDKASVENERNALHLRTRDGHDVTCVQVAGLIARRILCYVEAGASLARGQRYGFIRFGSRVDVYLPAGSRARVTIGDKVSASSTILAELP
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CH601_PARXL
Sequence: MAAKDVVFGDSARAKMVEGVNILANAVKVTLGPKGRNVVLERSFGGPTVTKDGVSVAKEIELKDKLQNMGAQMVKEVASKTSDNAGDGTTTATVLAQSIVREGMKYVASGMNPMDLKRGIDKAVFAAIEELRKISKPCTTNKEIAQVGAISANSDSSIGDRIAEAMDKVGKEGVITVEDGKSLQDELDVVEGMQFDRGYLSPYFINNPDKQVAVLENPFVLLHDKKVSNIRDLLPILEQVAKAGRPLLIIAEDVEGEALATLVVNNIRGILKTVAVKAPGFGDRRKAMLEDIAILTGGQVIAEETGLTLEKATLAELGQAKRIEVAKENTTIIDGAGEAANIEARVKQVRTQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGIVAGGGVALIRARTAIAGLKGANADQDAGIKIVLRAMEEPLRQIVTNGGEEASVVVAAVAAGTGNYGYNAATGEYVDLVDAGVVDPTKVTRTALQNAASVAGLLLTTDAAVCELPKEDAPMAGGMPGGMGGMGMDM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AKB9B_ARATH
Sequence: MENDPFLRQYQPSELKIASEFLTNWLPFLSKDLCKDCNHLLSNRIRSLDPAHCSNNTDKVDGECKTGSCSVVENMGSERASNNVDDNYDEKSENGEDCDNHSLGSWKGSEIVFGSFPEDFSSVLQSRPAVVETASPRMRWADMAQEDEFDEEEEEEEEERDSSRKGFDASSMKTPEKPKLSRDQRENLRLINVKRKKDFICLERVKGKIVNVLDGLELHTGVFSAVEQKRIVDQVYQLQEKGRRGELKKRTFTAPHKWMRGKGRETIQFGCCYNYAPDRAGNPPGILQREEVDPLPHLFKVIIRKLIKWHVLPPTCVPDSCIVNIYDEGDCIPPHIDNHDFLRPFCTISFLSECDILFGSNLKVEGPGDFSGSYSIPLPVGSVLVLNGNGADVAKHCVPAVPTKRISITFRKMDESKRPVWFTPEPDLQGIEPLPLDLNRSGSTSRFSRLNNHNGTNQRGHGRRGGGNGYDSRGYYNPERSSEHNDSGDWPSSQRRGMPRPSRRNYG
What is the function of this protein?
Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:28923956).  Modulates viral infection of the alfalfa mosaic virus (AMV) and the m6A abundance in its genomic RNAs (PubMed:28923956).
What are the official names of this protein?
RNA demethylase ALKBH9B, AtALKBH9B, Alkylated DNA repair protein alkB homolog 9B, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 9B.
What is the protein family that this protein belongs to?
Belongs to the alkB family.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Cytoplasmic granule.
Protein: RS3A_IXOSC
Sequence: MAVGKNKGLSKGGKKGVKKKIVDPFTRKDWYDVKAPTMYTVRNIGKTFVNRTQGTKIASEGLKGRVFEVSQADLTNGEDAYRKFRLIAEEVQGRNVLTNFHGMDLTTDKLRSMVKKWQTLIEATVDVRTTDGYLLRMFCIGFTKKCANQLKKTCYAQHNQVRLIRKKMTEMMVVEVSSSNLKDVVNKLIPGSIGKDIEKSCQHIYPLHDVLIRKVKVLKKPKFELGKLLELHGEGTSKGGAASTAAVAKGEEGVKVDRPEGYEPPVLETV
What are the official names of this protein?
40S ribosomal protein S3a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_GRAFK
Sequence: MEAFVGTGVALITPFKEDLSIDTEALSNLVKYQIENGIEYLVVLGTTAESATLTQDEKELIKKVVKEANAGELPLVLGVGGNNTAGVVEELQIADLDGFDAILSVSPYYNKPTQEGIYRHFEAISKASPLPIILYNVPGRTSSNVLPETINRIARNLKNVIGVKEAAGDIVQAMKMISLVPDDFKVISGDDMITLPMTLAGGKGVISVIGQGLPKEFSNMVRAGLEGKVSEAYQLHYKIAPSIEFIFAEGNPAGIKTLLAKKGIISNTLRLPLVEATETLQSKINSFVDNF
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VASH1_HUMAN
Sequence: MPGGKKVAGGGSSGATPTSAAATAPSGVRRLETSEGTSAQRDEEPEEEGEEDLRDGGVPFFVNRGGLPVDEATWERMWKHVAKIHPDGEKVAQRIRGATDLPKIPIPSVPTFQPSTPVPERLEAVQRYIRELQYNHTGTQFFEIKKSRPLTGLMDLAKEMTKEALPIKCLEAVILGIYLTNSMPTLERFPISFKTYFSGNYFRHIVLGVNFAGRYGALGMSRREDLMYKPPAFRTLSELVLDFEAAYGRCWHVLKKVKLGQSVSHDPHSVEQIEWKHSVLDVERLGRDDFRKELERHARDMRLKIGKGTGPPSPTKDRKKDVSSPQRAQSSPHRRNSRSERRPSGDKKTSEPKAMPDLNGYQIRV
What is the function of this protein?
Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function (PubMed:29146869, PubMed:31270470, PubMed:31235910, PubMed:31171830, PubMed:31235911).  Critical for spindle function and accurate chromosome segregation during mitosis since microtuble detyronisation regulates mitotic spindle length and postioning (PubMed:31171830).  Acts as an angiogenesis inhibitor: inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis (PubMed:15467828, PubMed:16488400, PubMed:16707096, PubMed:19204325).  This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts (PubMed:15467828, PubMed:16488400, PubMed:16707096).
What are the official names of this protein?
Tubulinyl-Tyr carboxypeptidase 1, Tubulin carboxypeptidase 1, Tyrosine carboxypeptidase 1, TTCP 1, Vasohibin-1.
What is the protein family that this protein belongs to?
Belongs to the transglutaminase-like superfamily. Vasohibin family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Note=Mainly localizes in the cytoplasm (PubMed:27879017). Some fraction is secreted via a non-canonical secretion system; interaction with SVBP promotes secretion (PubMed:27879017).
Protein: MUTS_BRUME
Sequence: MEAKVEEKEPEPVENAGPDAPVRLTPMMEQYIEIKAANVDSLLFYRMGDFYELFFDDAVAASAALGITLTKRGKHLGEDIPMCGVPVHAADDYLQKLIAKGYRVAVCEQVEDPAEAKKRGSKSVVKRDVIRLVTPGTLTEEKLLDPAQANFLMAMGRTRGDGALALAWIDISTGTFRVAETTPDRLFADIMRVDPRELVVADSAFHDEELRPVFDLIGKAVTPQPATLFDSAAAQTRIQHYFNVATLDGFGQFSRPELSAISGAIAYIEKTQISERPPLMRPEREHEGGTLFIDPATRASLELARTMSGNRDGSLLKAIDRTVTGGGARLLAERLTAPLTSPKEIALRLDSVSWCLSEQTLCEALRLELKGVPDMPRALSRLAVGRGGPRDLGALACGFEAAGGIASLLDGALLPDELAAAREAIEKMPAGFAAHLDRALADELPLLKRDGGFVREGYNSELDEMRALRDQSRRVIAGLQADYIEETGIKSLKIKHNNVLGYFIEVTANNSGAMTDTDEAKSRFIHRQTMANAMRFTTTELAELESKIANAADRALSIELAIFEELTAEAVAHADSIRAAASALSVFDVSTALAVLAEEQGYCRPHVDDSLSFNIVAGRHPVVEQALRRQAANPFVANDCDLSPQRDGGDGAIWLLTGPNMGGKSTFLRQNALIAILAQMGSFVPAGSAHIGVVDRLFSRVGASDDLARGRSTFMVEMVETAAILNQAGEHSLVILDEIGRGTATFDGLSIAWAAVEYLHEKNRCRALFATHFHEMTALSEKLERLSNVTMRVKEWDNDVIFLHEVAKGAADRSYGVQVARLAGLPEAVVNRARDVLHQLEAGETSGKADRLIDDLPLFSVMLQQEKPKPQIQAKDSELANAVAAISPDELTPREALDLIYKLKELAGKA
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: SURE_PSESM
Sequence: MRILISNDDGVNSPGLAALYAALADYTECVVIAPDQDKSGASSSLTLDRPLHPQTLANGFISLNGTPTDCVHLGIHGLLEREPEMVVSGINLGANLGDDVLYSGTVAAALEGRFLQRPSFAFSFLSRQPDNLATAAHYARLLVEAHEQFDLPPRTVLNVNIPNLPLEHIRGIQLTRLGHRARAAAPVKVVDPRGRAGYWIAAAGDVEDGGAGTDFHAVVQGYVSITPLQLDRTYQDGFSSLNNWLEGRR
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RB11E_LOTJA
Sequence: MAGYKADDEYDYLFKLVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATKSLNIDGKVIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDVTRSTTFETAGRWLKELRDHTDPNIVVMLIGNKSDLRHLVTVSTEDGKAFAEKESLYFMETSALEATNVENAFSEVLTQIYRIVSKRAVEAGDRPSTSVVPSQGQTINVNEDSSVLNRYRCCSN
What are the official names of this protein?
Ras-related protein Rab11E.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: DAPB_CORDI
Sequence: MAIKVGVLGAQGRVGQAIVAGVTAAYDLELVAEVDRGDSLDVLVQSGAEVIVDFTTPDSVMDNLEFCISHGIHCVVGTTGFTPERLEIVKKWAEEKGNTGVLIAPNFAISAVLTMAFARQAARFFDSAEVVECHHPNKLDAPSGTAIHTAEGIAQARREAGMPTQPDATEQSLDGARGADVGGVKVHAVRMTGMVAHEEVIFGGPGQSLTIRQDSYDRTSFVPGVLVGVRNVAQHLGLTVGLEHYLDI
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19B_DROME
Sequence: MPGVTVKEIDQHVLTKNMAAFLKKSGKIFVPEQAVYMKTGKFKETAPTDDDWFYTRCASIMRHLYLRSPAGVGAFTKVYSGRKRNGVRPSKHCRSSDGCIRKALQALEAANMVERHPDGGRKLTPQGQRNLDRIANKIVAKQRERSAPVSMIITT
What are the official names of this protein?
40S ribosomal protein S19b.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS19 family.
Protein: RL7_THENN
Sequence: MTIDEIVEAIEKLTVSELAELVKKLEDKFGVTAAAPVAVAAAPVAGAAGAAQEEKTEFDVILKSFGQNKVQVIKVVREITGLGLKEAKDLVEKAGTPDAVIKSGVSKEEAEEIKKKLEEAGAEVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: PGPS1_BOVIN
Sequence: MAAAAAAAAGPVFWRRLLGLLPGRPGLAALLGRLSDRLGRNPDRRRRRSPWLLLAPLLSPAVPVVTSPPCCLCAEGVHRFQWIRNLVPEFGVSSSHVRVLSSPAEFFELMKGQIKVAKRRVVMASLYLGIGPLEQELVDCLESTLEKSLQAKFPSGLRVSILLDFTRGSRGRKNSRTMLLPLLQRFPEQVRVSLFHTPNLRGLLRLLIPERFNETIGLQHIKVYLFDNNVILSGANLSDSYFTNRQDRYVFLQDCPEIADFFTELVDAVGDVSLQLQGDDTVQMVEGMVHPYKGDRAAYCRAANKRVMDVINSARMRQQMLHAQTFHSDPLLTQEDAAAAGDRRPAPDTWIYPLIQMKPFEIQIDEIVTETLLTEAERGAKVYLTTGYFNLTQAYMDLVLGTRAEYQILLASPEVNGFFGAKGVAGAIPAAYVHIERQFYSEVCSLGQQERVQLQEYWRRDWTFHAKGLWLYLAGSSLPCLTLIGSPNFGYRSVHRDLEAQIAIVTESRALQQQLHQEQEQLYRRAGVVSSATFEQPSRQVKLWVKMVTPLIKNFF
What is the function of this protein?
Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
What are the official names of this protein?
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial, Phosphatidylglycerophosphate synthase 1, PGP synthase 1.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y392_STAAB
Sequence: MGYLKKVGMCISLLIVIIFVTSCGGGNKITGDSKETQIKKSFAKTLDMYPIKNLDDLYDKEGYRDGEFKKGDKGTWGISSAMVKQPKGKIMRSRGMYLFLNRNTRTAKGYFIVDVTSNDTLKKTEDKEKRYPVKMVNNKIIPIGPINDEGIKKEIENFKFFSQYGDFKGLKNYQNGDYSYNSEAPTYSAKFQLSNDDYNVKQLRKMYDIQTKKAPKLLLKCTGDLKGSSIGHKDIEFTFVENQEENVFFTDSLEFTPSEDY
What are the official names of this protein?
Uncharacterized lipoprotein SAB0392.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: GLPK_BACMK
Sequence: MKKYILSLDQGTTSSRAILFNKEGKIVHSAQKEFTQHFPKPGWVEHNAQEIWGSILAVIATCLSEADVKPEQIAGIGITNQRETAVVWDKTTGKPIYNAIVWQSRQTVEICDELKEKGYSEMVREKTGLLIDAYFSGTKVKWILDNVEGAREKAENGELLFGTIDTWLVWKLSGGKAHITDYSNASRTLMFNIHDLQWDDELLDMLTVPKSMLPEVRQSSEIYGETIDYHFFGQNVPIAGVAGDQQAALFGQACFGEGMAKNTYGTGCFMLMNTGEKAVASEHGLLTTIAWGLDGKVNYALEGSIFVAGSAIQWLRDGLRMFKDASESEVYASRVESTEGVYIVPAFVGLGTPYWDSEVRGAMFGVTRGTTKEHFIRATLESLAYQTKDVLCAMEADSGIELNTLRVDGGAVKNNFLMKFQSDILDVPVERPVINETTALGAAYLAGLAVGYWKNQDEIKAQWHMDKRFEPTMEAETSEELYAGWKKAIEATKAFK
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: BET1L_PONAB
Sequence: MADWARAQSPGAVEEILDRENKRMADNLASKVTRLKSLALDIDKDAEDQNRYLDGMDSDFTSMTGLLTGSVKRFSTMARSGRDNRKLLCGMAVGLIVAFFILSYFLSRART
What is the function of this protein?
Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex.  Required for the integrity of the Golgi complex (By similarity).
What are the official names of this protein?
BET1-like protein.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type IV membrane protein. Golgi apparatus, trans- Golgi network membrane. Note=Present throughout the Golgi apparatus, with increasing concentration from cis-Golgi to the trans- Golgi face of the stacks.
Protein: LIPB_BRUAB
Sequence: MPTGKLRQKPPYAAIMTNSPVTPSTETQQPKRDALYARFLPQEADAPPVEWLIAEGLTDYEEALAFMEARVQATREGTASELVWLVEHPPLYTAGTSANAEDLLTPDRFPVFNTGRGGEYTYHGPGQRVAYVMLDLKRRREDVRAFVASLEQWIIETLAAFNIKGERREDRVGVWVVRPEKPRLADGSMCEDKIAAIGIRLRRWVSFHGIAINVEPDLSHYGGIVPCGISEHGVTSLVDLGLPVTMGDVDVALGKAFESVFGPRQTK
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS7_FIPV
Sequence: MLVFVHAVLVTALILLLIGRIQLLERLLLSHLLNLTTVSNVLGVPDSSLRVNCLQLLKPDCLDFNILHKVLAETRLLVVVLRVIFLVLLGFSCYTLLGALF
What is the function of this protein?
May function in the formation of membrane-bound replication complexes or in the assembly of the virus.
What are the official names of this protein?
Non-structural protein 7a, ns7a, 11 kDa protein, Accessory protein 7a.
What is the protein family that this protein belongs to?
Belongs to the coronaviruses ns7/ns7a protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: KIF3B_HUMAN
Sequence: MSKLKSSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIPNSFDHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIENFIPLEEKSKIMNRAFFDEEEDHWKLHPITRLENQQMMKRPVSAVGYKRPLSQHARMSMMIRPEARYRAENIVLLELDMPSRTTRDYEGPAIAPKVQAALDAALQDEDEIQVDASSFESTANKKSKARPKSGRKSGSSSSSSGTPASQLYPQSRGLVPK
What is the function of this protein?
Microtubule-based molecular motor that transport intracellular cargos, such as vesicles, organelles and protein complexes.  Uses ATP hydrolysis to generate force to bind and move along the microtubule (By similarity).  Plays a role in cilia formation (PubMed:32386558).  Involved in photoreceptor integrity and opsin trafficking in rod photoreceptors (PubMed:32386558).  Transports vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit GRIN2A into neuronal dendrites (By similarity).
What are the official names of this protein?
Kinesin-like protein KIF3B, HH0048, Microtubule plus end-directed kinesin motor 3B.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin II subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, cilium. Cell projection, dendritic spine.
Protein: RK20_ORYSI
Sequence: MTRVPRGYIARRRRAKMRSFASNFRGAHLRLNRMITQQVRRAFVSSHRDRVRQKRDFRRLWISRINAATRIHKVFDNYSKLIHNLYKKELILNRKILAQVAVLNPNNLYTISNKIKIIN
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit (By similarity).
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CINA_STRTD
Sequence: MKAELIAVGTEILTGQITNTNAQFLSEKLAELGIDVYFHTAVGDNENRLLSVLDQSSKRSDLVILCGGLGPTEDDLTKQTLAKFLGKELIFDEEASKKLDSFFATRPKHTRTPNNERQAQIVEGAVPLQNLTGLAVGGIITVEGVTYVVLPGPPSELKPMVNQELIPALTENHTTLYSRVLRFFGVGESQLVTIIKDLIVNQTDPTIAPYAKVGEVTLRLSTKASSQEEADRKLDVLEEQIRSTKTLDGKSLSDLIYGYGESNSLAYEVFYLLKKYGKTITAAESLTAGLFQASVADFPGASQVFKGGFVTYSMEEKAKMLGIPLSKLEEHGVVSHFTAEKMAEGARVKTDSDYGIALTGVAGPDALEGHQAGTVFIGIADRNQVRSIKVVIGGRSRSDVRYISTLYAFNLVRQALLQEDNSI
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: NTPPA_MOOTA
Sequence: MSKLVLASASPRRRELLARLGLPFTIQPSRIDESVYRHLPPAARVEALALAKARAVAAGLTDALVLGADTLVVCEGRVLGKPDSPAAAARMLAFLSGRTHTVYTGVAVVQAPRGPEGVTHARTAVTFRHLTPDQIEAYVATGEPLDKAGAYGIQGRGALLVAGIEGDYFNVVGLPLVQVEELLAIFGVDVWGRV
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.