PharMolix/UniProtQA huggingface dataset:
Protein: DCUP_ECO5E
Sequence: MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAGDFMSLCKNAELACEVTLQPLRRYPLDAAILFSDILTVPDAMGLGLYFEAGEGPRFTSPVTCKADVDKLPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGSSKAFTVIKKMMYADPQALHALLDKLAKSVALYLNAQIKAGAQAVMIFDTWGGVLTGRDYQQFSLYYMHKIVDGLLRENDGRRVPVTLFTKGGGQWLEAMAETGCDALGLDWTTDIADARRRVGNKVALQGNMDPSMLYAPPARIEEEVATILAGFGHGEGHVFNLGHGIHQDVPPEHAGVFVEAVHRLSEQYHR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_ACTSZ
Sequence: MTQQSILFIDRDGTLIDEPKTDFQIDSLEKLKFEPNVIPALLKLKNKYRFVMVSNQDGLGTSSFPQADFDKPHNAMMALFNSQGIEFDDVLICPHKPEDGCDCRKPQTKLLQKYIERELFDPATSFVIGDRATDVQLAENLGIRAIQYHPEKMNWDLIAEKLLGESVTNNGDRTPRYAEVARKTKETDIKVQVWLDETGVNDIKTGVGFFDHMLDQIATHGGFRMNVSCKGDLWIDEHHTVEDTALALGTALKQAIGDKRGIARFGFVLPMDECKAECTMDLSGRPFIKFKADFKRDKVGDFSTELTEHFFQSIAFTMLATLHLAVEGDNEHHKIESLFKVFGRTLRQCIRIEGNELPSSKGVL
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisB.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR12_RANMC
Sequence: MPTIKQLIRNTRQPIKNVTKSPALRGCPQRRGTCTRVYTITPKKPNSALRKVARVRLTSGFEITAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGTLDAVGVKDRQQGRSKYGVKKPK
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HSLO_PROM4
Sequence: MNDTLVRATAANGGIRLVAAITTNALKEAKSRHKLSYLTSALMGRAMSASLLLASSMKVLHGRVTLKIQSDGPIKGLTVDACRDGSVRGFLGNPSLELDLVKSKEGHHCFDFANATGKGYLHVIRDIGEGDPYSSTVELVGGGIGEDIASYLLHSEQTPSAVFVGEKIKHKELVCSGGLIAQILPKASQDRSLAELLEENCNTITSFSERLFEYKDNLSGLLKDLFYNLNPEIVKGPSARQEIKYRCKCSRDRSISALKLLGNSEIKSILNEDKKAEITCEFCKNVYQIEEEELRSLVDI
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_YERPB
Sequence: MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKAGSELGLKAKEIMDAGKLVTDELVIALVKERITQEDCRDGFLLDGFPRTIPQADAMKEAGIKVDYVLEFDVPDELIVERIVGRRVHAASGRVYHVKFNPPKVEDKDDVTGEELTIRKDDQEATVRKRLIEYHQQTAPLVSYYHKEADAGNTQYFKLDGTRNVAEVSAELATILG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LECM2_ERYPO
Sequence: MERFIFAALLVVALSLSGTGADPQCLPGWSSSDGYCYKVFKEYKRWDDAEMFCRQEVEGGHLVSIHSKTEAKFLARLVFRKFILLNVWIGLSSPGKHGIWRWSDGSSFYYTSWAFGEPNNFLWNEYCVGLMSITGHRKWSDQNCRSKRYFICKAQPQSEGSTW
What is the function of this protein?
Mannose-binding lectin which recognizes specific carbohydrate structures and agglutinates a variety of animal cells by binding to cell-surface glycoproteins and glycolipids.  May be a calcium-dependent lectin (By similarity).
What are the official names of this protein?
C-type lectin lectoxin-Lio2, CTL.
What is the protein family that this protein belongs to?
Belongs to the true venom lectin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DCP2_CAEEL
Sequence: MEISTENWCKKPKNRSIFSKNISFQKQNKSTEEPPSSVQKLLASLQQAQNKSDLSEQPSTSKPKKNEKRKKAVAQAPASAPAPGPEEKKKQPKRASVGARMQQQAENARISQTKRPRQVSTSKGSSRNTTAPEQQNYQQQQQQYKGPRIPTDILDELEFRFISNMVECEINDNIRVCFHLELAHWYYIDHMVEDDKISGCPNVGSRDFNFQMCQHCRVLRKYAHRADEVLAKFREYKSTVPTYGAILVDPEMDHVVLVQSYFAKGKNWGFPKGKINQAEPPRDAAIRETFEETGFDFGIYSEKEKKFQRFINDGMVRLYLVKNVPKDFNFQPQTRKEIRKIEWFKIDDLPTDKTDELPAYLQGNKFYMVMPFVKDIQIYVQKEKEKLRRRKAEAVQSTPSSSIFSQLFPAQPPPPVPEDATPTRPMYKRLTSEELFSAFKNPPAGEVARPTLPDMSPAVNGLDTLAVLGICTPLKPGASLNEFSGAPQNCPMISEEAGSPADPSAEIGFAMPMDLKQPVVTSDHPWQHHKISDSSAPPQTLESHQGWLDTQLVNTIMHSPNHPLPPTSNSPATPTAVLGHLIGKPIQPQAILPQAATPTALGSAEKPKSSRISLSDNSAFKAISSTQKQSIPKATAAPPSTEKTRSASLSGSSQVVGKPARNLFNSVVSPVSSGIQSIQGDGGAWEDVWFREQLAATTTAGTSISSLAASNQELAMINREETPIEDPYFKQQAYQKAQKAQSLIPACSQWTNSIKLDIDYVVGPLSFWMQQFSTKSPVSGTGPQLP
What is the function of this protein?
Decapping metalloenzyme that catalyzes the cleavage of the cap structure on mRNAs (PubMed:16199859).  Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP (PubMed:16199859).  RNA-decapping enzyme although it does not bind the RNA cap (PubMed:16199859).  May contribute to gene regulation in multiple RNA pathways including monomethylguanosine- and trimethylguanosine-capped RNAs (PubMed:16199859).  In oocytes, may play a role in the response to stress induced by heat shock, osmotic stress and anoxia (PubMed:18439994).  Required for the developmental axon guidance and regrowth of PLM touch receptor neurons (PubMed:31983639).  Early in embryogenesis, plays a role in ciliary shape formation in sensory neurons (PubMed:28887031).  Promotes survival at high temperatures (PubMed:25061667).
What are the official names of this protein?
m7GpppN-mRNA hydrolase dcap-2, Nudix hydrolase 5, mRNA-decapping enzyme 2.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. DCP2 subfamily.
What are the subcellular locations of this protein?
Cytoplasmic granule. Cytoplasm, perinuclear region. Note=Localizes to perinuclear puncta in pachytene-stage germ cells (PubMed:18439994). Diffusely localized to cytoplasmic puncta in maturing oocytes (PubMed:18439994).
Protein: NAPA_SALG2
Sequence: MKLSRRSFMKANAVAAAAAAAGLSVPGVARAVVGQQEAIKWDKAPCRFCGTGCGVLVGTQQGRVVACQGDPDAPVNRGLNCIKGYFLPKIMYGKDRLTQPMLRMKDGSYHKDGEFTPVSWEQAFDVMEEKFKTSLKEKGPEAIGMFGSGQWTIWEGYAAAKLFKAGFRSNNIDPNARHCMASAVVGFMRTFGMDEPMGCYDDIEQADAFVLWGSNMAEMHPILWSRITNRRLSDPNVKVAVLSTFQHRSFELADNGIVFTPQSDLVILNYIANYIIQNNAVNQDFFTKHVNLRKGATDIGYGLRPTHPLEKAAKNPGSDASEPMSFDEYKAFVAEYTLDKTAEMSGVPKDQLEQLAQLYADPNKRVISYWTMGFNQHTRGVWANNLVYNLHLLTGKISQPGCGPFSLTGQPSACGTAREVGTFSHRLPADMVVTNEKHRDICEKHWQIPAGTIPAKVGLHAVAQDRALKDGKLNVYWVMCNNNMQAGPNINEDRMPGWRDPRNFIIVSDPYPTVSALSADLILPTAMWVEKEGAYGNAERRTQFWRQQIKAPGEAKSDLWQLVQFSRRFKTEEVWPEALLAQKPELRGKTLYDVLFATPAVSKFPLSELKEDQLNDESRELGFYLQKGLFEEYAWFGRGHGHDLAPFDDYHNARGLRWPVVEGKETQWRYSEGNDPYVEAGEGYKFYGKPDGKAVIFALPFEPAAESPDNEYDLWLSTGRVLEHWHTGSMTRRVPELHHAFPEAVVFIHPLDAKARDLRRGDKVKVSSRRGEVISIVETRGRNRPPQGLVYMPFFDTAQLVNNLTLDATDPLSKETDFKKCAVKLAKV
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: HSLV_JANSC
Sequence: MAKEEFPGWHGTTIIGVRKGGKVVVAGDGQVSLGPTVIKGSARKVRRLSPGGYDVVCGFAGSTADAFTLLERLEAKLEATPGQLQRASVELAKDWRTDKYLQKLEAMLIVTDGSELYIITGAGDVLEPEHDIAAIGSGGNFALAAARGMMDSDKDAEAVARDAMAIASDICVYTNGNLTVETISA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_CLOB8
Sequence: MKIKAYAKINIALDIVGKREDGYHILKMIMQTIDLYDIIEIEKTESEIRLNCNKHYVPTDERNLAYKAAKIFKETYSISQGVDIKLTKNIPVSAGLAGGSTDAAGVLKLMNKMFNVNASDEELKSIGLRLGADVPYCIKGGTALCEGIGEKITQLKSFKDKIIVLVKPPFGVSTKEVYKCFDLSKVVFHPKIDSLIENMNNDDVYFVANNMKNLLENVTLRKHRVITNIKEEMKSIGSIGTMMSGSGPTVFALFDDMLKAQLCYDEMKKKYKDVFITRTI
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: RL11_PYRAE
Sequence: MSKRVVTVPLQGGKVAVNPQFQDALKQIGLDPNAVVQRVQEELKKVGKYPVQKVEVEVVSPSKYEVKIYLPPIGDLLLKLFGKDTGAHDARNEVIGNLSFAQLVEIALLKKDELKSKTLKSAVKQLLSTCKAMGVTVDGRKAEEVLRDVDGGKYDEIINKFEKQWQQ
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: PCDGD_PANTR
Sequence: MRRAREAEMMKSQVLFPFLLSLFCGAISQQIRYTIPEELANGSRVGNLAKDLGLSVRELPTRKLRVSAEDYFNVSLESGDLLVNGRIDREKICGRKLECALEFETVTENPMNVFHVVVVIQDINDNAPRFVAKGIDLEICESALPGVKFSLDSAQDADVEGNSLKLYTINPNQYFSLSTKESPDGSKYPELLLEKPLDREHQSSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAPVFSQEVYRVSLQENVPWGTSVLRVMATDQDEGINAEITYAFLNSPISTSLFNLNPNTGDITTNGTLDFEETSRYVLSVEAKDGGVHTAHCNVQIEIVDENDNAPEVTFVSFSNQIPEDSDLGTVIALIKVRDKDSGQNGMVTCYIQEEVPFKLESTSKNYYKLVIAGALNREQTADYNVTIIATDKGKPALSSRTSITLHISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNGRVSYSILASDLEPRELLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIFADSLQEVLPDLSDRPEPSDPQTELQFYLVVALALISVLFLLAVILAIALRLRRSSSLDTEGCFQTGLCSKSGPGVPPNHSEGTLPYSYNLCVASHSAKTEFNFLNLTPEMAPPQDLLCDDPSMVVCASNEDHKIAYDPSLSSHQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin gamma-B1, PCDH-gamma-B1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: NANT_SALPK
Sequence: MSTSTQNIPWYRHLNRAQWRAFSAAWLGYLLDGFDFVLIALVLTEVQSEFGLTTVQAASLISAAFISRWFGGLLLGAMGDRYGRRLAMVSSIILFSVGTLACGFAPGYTTMFIARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGFLISGFSVGAVVAAQVYSLVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHAGKAPVRTMVDILYRGEHRIINMLMTFAAAAALWFCFAGNLQNAAIVAGLGLLCAVIFISFMVQSSGKRWPTGVMLMLVVLFAFLYSWPIQALLPTYLKTELAYDPHTVANVLFFSGFGAAVGCCVGGFLGDWLGTRKAYVCSLLASQILIIPVFAIGGTNVWVLGLLLFFQQMLGQGIAGILPKLIGGYFDTDQRAAGLGFTYNVGALGGALAPILGALIAQRLDLGTALASLSFSLTFVVILLIGLDMPSRVQRWLRPEALRTHDAIDDKPFSGAVPLGSGKGAFVKTKS
What is the function of this protein?
Catalyzes the proton-dependent transport of sialic acid.
What are the official names of this protein?
Sialic acid transporter NanT, Sialic acid permease, Sialic acid/H(+) symporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RECO_THEVB
Sequence: MGRTYRTIGINLKAMPLGESDRLLSVFSRDRGLLKLVAPHSRGSRSRLGGRVDLFVVNDLFISPGRNLDRILQAETVATYQGLHHQLTTLTAAQYLGEVVLYQIHPQQPQPELFDWFCATLDQLQGASSRAALAILVRGLCGILRLGGIAPEWYQCHESGCKIAVPTADTDWRLGFSFAGGGVFRIRADHPVGNESVAGAGGDRQLTASEVRLGQWLAMPTTQFLARDEFLTQAEAYPLSVWLSLERVLRQYLQFHLEQPLRVPPLLDSCFSPVAVSQP
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: YQGF_STAAN
Sequence: MLQHKILGLDVGSRTVGIAISDIMGWTAQGLDTLRINEENNELGIDQLVDIIKKHNVGTVVIGLPKNMNNSIGFRGEASLTYKEKLLEAYPSIEIVMWDERLSTMAAERSLLEADVSRQKRKQVIDKMAAVFILQGYLDSLH
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FATB_GOSHI
Sequence: MVATAVTSAFFPVTSSPDSSDSKNKKLGSIKSKPSVSSGSLQVKANAQAPPKINGTVASTTPVEGSKNDDGASSPPPRTFINQLPDWSMLLAAITTIFLAAEKQWMMLDWKPRRPDMVIDPFGIGKIVQDGLVFSQNFSIRSYEIGADQTASIETLMNHLQETAINHCRSAGLLGEGFGATPEMCKKNLIWVVTRMQVVVDRYPTWGDVVQVDTWVSASGKNGMRRDWLVSNSETGEILTRATSVWVMMNKLTRRLSKIPEEVRGEIEPFFMNSDPVLAEDSQKLVKLDDSTAEHVCKGLTPKWSDLDVNQHVNNVKYIGWILESAPLPILESHELSALTLEYRRECGRDSVLQSLTTVSDSNTENAVNVGEFNCQHLLRLDDGAEIVRGRTRWRPKHAKSSANMDQITAKRA
What is the function of this protein?
Plays an essential role in chain termination during de novo fatty acid synthesis.  High thioesterase activity for palmitoyl-ACP versus other acyl-ACPs.
What are the official names of this protein?
Palmitoyl-acyl carrier protein thioesterase, chloroplastic, 16:0-acyl-carrier protein thioesterase, 16:0-ACP thioesterase, Acyl-[acyl-carrier-protein] hydrolase, PATE.
What is the protein family that this protein belongs to?
Belongs to the acyl-ACP thioesterase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FOSB_STAAT
Sequence: MLKSINHICFSVRNLNDSIHFYRDILLGKLLLTGKKTAYFELAGLWIALNEEKDIPRNEIHFSYTHIAFTIDDSEFKYWHQRLKDNNVNILEGRVRDIRDRQSIYFTDPDGHKLELHTGTLENRLNYYKEAKPHMTFYK
What is the function of this protein?
Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin.  L-cysteine is probably the physiological thiol donor.
What are the official names of this protein?
Metallothiol transferase FosB, Fosfomycin resistance protein.
What is the protein family that this protein belongs to?
Belongs to the fosfomycin resistance protein family. FosB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU3C_CITSI
Sequence: MFLLYKYDIFWAFLIISSVIPILAFLISAVLAPINKGPEKLSSYESGIEPMGDAWLQFRIRYYMFALVFVVFDVETVFLYPWAMSFDVLGVPVFIEAFIFMLILIVGLVYAWRKGALEWS
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PYRR_STRSV
Sequence: MKTKEVVDDITMNRAITRITYEIIERNKDLNQVVLAGIKTRGVHLAHRIQKRLAQLENIDIPVAEVDTKPFRDDIKVEEDTTVIPVDITDRQVILIDDVLYTGRTIRAAIDNLVSHGRPSRVGLAVLVDRGHRELPIRADYVGKNIPTSQTEEIIVEMTETDGQDRVLIMGE
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: RSMH_LACE2
Sequence: MGFIMEFKHKSVLLEETIDNLNIKPDGIYVDGTLGGAGHSYQIAKRLTGGGRLIGIDQDADAIAAATERLKEFEERVTIVRNNYCNMDKVLDELGIDKVDGILLDIGVSSYQLDTASRGFTYNVDTALDMRMDQRQEMTAKDLVNTYSEMELFRIIRDYGEDRFAKNIAKHIVAARKEKPIETTFELNEIIKASIPAKVRATGGHPSKRTYQAIRIELNRELDVLENSIDMMIDRLNPQGRLCIITFHSLEDRIVKARFRNNENPCTCPPDFPVCVCGKKSKGKVITRKPIVPGDEELNENQRSKSSKLRVFERI
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_KLEP7
Sequence: MQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLISPHVNKDARDQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: CCD39_MOUSE
Sequence: MCSEFLSELHWEDGFAIPVANQENKILEDQLAKLREEKSNLQDQLHDYEERINSMTSHLKNVNQEFLFTQSLYKARESEIESEEHFKAIAERELGRVKNETQLLEKEMAIIRERKSQMENNIFKTTQKLDDLKCQMNWDQQALEAWLEESAHKDSDSLTLQKYSQQDDNKIRALTLQLEKLTMEYNEKRKLLDSELTETLSAQLELDKAAQDFRKIHLERQELIQQWENTIEQMQRRDQEIDNCALALSRIKQEAREKEGVVKEKIKFLENEVENNIEYERKISVAERKVSKCRMDYQRHEGNRSQLKDELDTLKTTLNRTSSDLQALRKNISKVKKDIFDETLRLQKLKHHNEVVKHKLKMITEKTLSIEEKATNMEDMLKEEEKGLKEVEVQLGIVKDVLFKKVQELQNEIAKEKALVSEIEGTRSSLKHLNKQLHKLDFETLKQQEIMYSQDFYIQQVERRMSRLKGEINSEEKQALEAKILELKKTMDEKKSTLSLLESQIKKLHNDLYFIKKSNGKNNDEKESLMNKISELNLFIDRSEKELSKAKAVKEDMMIEDNLLKLQVKRARELLYSKAEEVLSLEKRKQQLGKDMEERAEEIKVHKAMLTSQIRCVEQQRKTMSSEFHERLSKIDKLKNRYEILTVVMLPPEGEEEKTQSYYVIKAAQEKEELQREGDSLDAKINKAEKEIYALQNTLQVLNSCNSNYKQSFKKVTPSSDEYALKIQLEEQKRTADERYRCKQRQIRELQEDIQSMENTFEVIGHLANNAKEKLTEKQTLAFQLRKETEEQKPKLQRITKQCGRLRREIRILKQTDNETLEEQDIQLREIIQFHKDIDQMLVNAMENAEIHAIFKTYFEQNGLELPTARGPSSRSSSQSSSLSSFRSLEDVTLQSPPTAKVIQLRFPEPPPATNDSSRSASSGSNSNIPKEKKLSK
What is the function of this protein?
Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella.  Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella.  Not required for outer dynein arm complexes assembly.
What are the official names of this protein?
Coiled-coil domain-containing protein 39.
What is the protein family that this protein belongs to?
Belongs to the CCDC39 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Note=CCDC40 is required for localization to axonemes.
Protein: MUTS_HAEIE
Sequence: MISEENFQQHTPMMQQYLKLKAENPDTLLFYRMGDFYELFYDDAKKAAALLDISLTKRGQSAGQPIPMAGMPYHAVEGYLAKLVQLGESVAICEQIGDPATSKGPVERQIVRIVTPGTVSDEALLPERQDNLIAAVYQEKEKFGLATLDMTSGRFQLCEPADKETLRAELQRIVPVELLYCEEFNEMAAIEHCKGLRRRPIWEFELSTAITLLNRQFGTKDLRAFGVEKSPLGLSAAGCLLQYAKETQRTALPHIQSISLIQNQDCIQLDAATRRNLELTQNLSGGTENTLASVLDKCVTPMGSRLLKRWIHQPIRDVEKLKQRQQAIAEILNFDLVDELQPYLQLVGDMERILARVALRSARPRDLTRLRTALEQIPALRTIVQQKTPPFLTALFSQIADFSEQCDLLQRALIETPPLLIRDGGVIAEGYNTELDEWRMLSDGATQYLENLEKRERESTGIDTLKIGFNAVHGYYIQISQGQAHKAPIHYVRRQTLKNAERYIIPELKEYEDKVLKSKGAALALEKQLYDELFDLLLPHLGALQLASLALSELDVLVNLAERADTLNYVMPTFCDEVSVKIENGRHPVVEQVLKDPFIANPVELNHNRHLLIITGPNMGGKSTYMRQTALITLLAYIGSFVPADSARIGPIDRIFTRIGASDDLASGRSTFMVEMTEMANILHQATEQSLVLIDEIGRGTSTYDGLSLAWACAEWLAKKIRSLTLFATHYFELTALPEQLEGIVNIHLDALEHNNSIAFMHAVQDGAASKSYGLAVAALAGVPQSVIKLAKQKLTQLEKNSSHSADQQIQALREANHNQGELLFEQETDALREAIEKLDPDDLSPKQALAYLYQLKKMVG
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: APOE_TURTR
Sequence: MKVLWVALVITLLAGCQAEVEPEPEPEVQLGREWPRWQGSQPWEQALGRFWDYLRWVQTLSDQVQEELLSTQVIQELTVLMDETMKEVKAYREELEGQLGPIAQETQARVSKELQAAQARLASDMEDVRSRVAQYRSEVQALMGQTTDELRGRLASHLRKLRKRLLRDAEDLQKRLVVYRAGALEGSERSVSAIRERLGPLVEQGRVRAATVGTLASQTLRERAEAWHQKLRGRMEEMGTQARDHLEEMREQLEEVRAKVEEQGSQMRLQAEAFQARLKSWFEPLVEDMQRQWAGLVEKVQLAMATGPTSAPIENN
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: Y8866_DICDI
Sequence: MSPQQIQTAGINLSPQHNNTNNNNSNNNNNNNTNNNSNNTNNNNTNNNNNNNNNSNNNNINNNNNNNNTNTNANTNINNNNNNNNNNNNNNNNNNNINNNNNNINNNNINNNGNNVNLVNIGVPQLQQHLQGILSKQQLVNQQNSSIQQQIQQLANSIMITKQQIGQGQPNAQQQQQQLQQQQQLQNFQQLQQNLHNQGASLQSQAQQIQQMLNNNGNNLNNSNNNNNNNNSNSSSNNNNNNSSSNNSSSNNNSNNNNINNNNNNGNNNNNMGNNNNNMGNNNMGNNNMGNNNMNNNNMNNNNINNNNSNNNNNNNMNNNNNSNNNSNNMNNNNNNSNSNNNNNNNNNNNNNNNNMNNNNMNNNNNNNNNNMNNNNNNNNNNNNNNNNNNNMNNNNNMNMNNNMNNNNMNNNNNNNMNNNNMNNNNMNNNNMNNNNVNNNNMINNGQQPNQQQIQTGQSTNQQLHQQLQLLQQQQRASQQGFTPQQLQQLVNQPLTPFSNQIQNPFQQLPIQQPIQQLGNSGQFSNNNQNNMSNNGNNNNNNNSNNNINNNNNNNNNSNNNSNNNSNNNSNNNSNNNGNNNGNNNGNNNGNNNGNGNNNGNNNNNNNNNNNNNNNNYNPLNNNNIIGQNGMIINNSQILGSQNGVNNNNVQQFGNPQFFPYTQQPNQLPPNQQQNQSPQPSNMVSVSTTNINTNTSSPLSTDPSDEPSSKRVKKSSSKPSKSKGKK
What are the official names of this protein?
Putative uncharacterized protein DDB_G0286901.
Protein: LACA_STAAW
Sequence: MAIIIGSDEAGKRLKEVIKSYLLDNKYDVVDVTEGQEVDFVDATLAVAKDVQSQEGNLGIVIDAFGAGSFMVATKIKGMIAAEVSDERSGYMTRGHNNSRMITMGSEIVGDTLAKNVVKGFVEGKYDGGRHQIRVDMLNKMC
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacA.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.