PharMolix/UniProtQA huggingface dataset:
Protein: TYSY_GEOSW
Sequence: MRQYLQLLEDILENGVEKDDRTGVGTLSVFGRQLRFNLQEGFPLLTTKKLHIRSIIYELLWFLKGDTNVRYLQENGVTIWDEWADENGDLGPIYGAQWRSWKGADGKTVDQISWVIEEIKRNPNSRRLLVSAWNVAELDKMKLPPCHYAFQFYVADGKLSCMWQQRSVDTFLGLPFNIASYALLTHMIAQQCDLDVGELIFSGGDVHLYKNHLEQAKLQLTREPRPLPKLVIKRKPASIFEYEFEDFEIVDYDPHPHIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECOT1_LEIBR
Sequence: MSCCKMEAPYPHAESDEKRIVFALDPKGDDAERDQYRLQLIPGRVLEMSRNDAANHQTLSGSIEQHTVEGWGAPFFHVKLAKEAAATLMQVHSEDHVEKSRKFVALSNTPLVPYTSRYPVVVYLPKDAELRYSIWCGGEQMQATTE
What are the official names of this protein?
Ecotin-like protein 1, Inhibitor of serine peptidase 1, LbISP1.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I11 (ecotin) family.
Protein: MVP1_ASPOR
Sequence: MSLFGTSPEDSSAGNSAHRSKSSLFADEPSLGTGSNANLGSSSLFADDDDLSSGSPWNSNVNKRTARHKLVKTLLSDSDAPESYIDAYDLVLSAGDRVGAGIGLTSVREILSGSGISASDQEKILNIVVSGDIDSANGLGRGEFNVLLALVGLAQEGEDLTLDAVDDRRKKLPAPKSLYLDALRANQESGTPAPSQERPITPPRPASPQQAPNSAHSRRESMTGLESDPWGSPELHRGHAHAQLESDHPVLNGYGSVRSATNAWSSRVGEDNNPNEISNSNRANSQTDSAPSHGSGFGWGESLGNTPSDGGLGGTARAGLGGFGPPSSVHSDSNPRRRSLGIGRVASPPVEEHVTVTLLPEKEGMFMFQHRNYEVKSARRGSTVVRRYSDFVWLLDCLQKRYPFRQLPLLPPKRLSADSNAFLEKRRRGLVRFTNALVRHPVLSQEQLVIMFLTVPTELSVWRKQATISVQDEFTGRDLPPDLEDSLPSTLPDTFETVRGGVKRSAEIYINLCTLLERLAKRNEGLAADHLRFSLALQSLTEVTRDTYAIDTNDVPLLNEGIRATANHLSVSQSLLEDEARAWEEGVLEDLKRQRDCLVSVREMFDRRDRYARNNIPQLERRIENNERKLQDLRSRPQGTVKPGEIEKVEDAIIKDKESIVQQHARGVFIKECIRDEIVYFQQSQYHISRLHQEWSQERVKYAELQADNWRSLSDQVESMPLSG
What is the function of this protein?
Required for vacuolar protein sorting.
What are the official names of this protein?
Sorting nexin mvp1.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: IF2_ALKOO
Sequence: MSKIRVYQLAKKLGISNKELIDKLKELSIEVNSHMSTVDNENADVLIELFTEQNKEETKPNVDEKPPNQDTLTDNVNESAESIQNVDKKHFKKEINSTKNVTPNGNNKKDKKKKNKKDKRKNYIANNDVSAESKGEQVIQLKNKLTVKELSETLNKSASEIITKLIGLGIMATINQELDYDTASIIAAEFGIEVEPMTDIDAEEDVFDIIIEPDKPEDLKHRSPVVTVMGHVDHGKTSLLDAIRKTKVTNSEAGGITQHIGASEIKVNDKKIVFLDTPGHEAFTSMRARGAKVTDVAILVVAADDGVMPQTIEAISHAKAAEVPIIVAINKMDKPSANPDRVKQELADQGLLIEEWGGDVISVPVSARSGENIDALLEMVLLVSEMSELKANPNRKAIGTVIEAQLDVGKGPVATVLVQNGTLFIGDSVVIGNTYGRIRAMMNDSGKRVKVAGPSTAVEITGLSEVPEAGDQLFAVDDDKAAKAIVEKRINKIKEEQLKAGQKISLDALFSQMEQGQLKDLNLIIKADTQGSVEAVKQSLVKLSNDEVVINPIHGGVGGITESDVMLATASNAIIIGFNVRPTSNAASAAKKENVDIRTYRIIYKAIEDIEAAMKGMLDPEFVEEELGKAEVRATFKVPGAGTIGGCYVIEGKILRNAKIRLVRDNIVIHEGSIDSLKRFKDDAKEVATGYECGIGISQFNDLKEGDIIEAYHMKEIER
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYW_MYCPN
Sequence: MMKRALTGIQASGKQHLGNYLGVMQSLIELQEQCQLFVFVADLHSITVDFQPQALKQNNFDLVRTLLAVGLDPQKACLFLQSDLLEHSMMGYLMMVQSNLGELQRMTQFKAKKAEQTRNPNGTLNIPTGLLTYPALMAGDILLYQPDIVPVGNDQKQHLELTRDLAQRIQKKFKLKLRLPQFVQNKDTNRIMDLFDPTKKMSKSSKNQNGVIYLDDPKEVVVKKIRQATTDSFNKIRFAPKTQPGVTNMLTILKALLKEPVNQSLTNQLGNDLEAYFSTKSYLDLKNALTEATVNLLVNIQRKREQISREQVFNCLQAGKNQAQATARTTLALFYDGFGLGSQNIK
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSUG_RUBXD
Sequence: MRPVQPAPEVAEALEGGRPVVALESTLISHGLPRPDNLRVARALEEAVRREGAVPATVGVVGGVARVGLGPEELELLASGEVPKLSARDLPAAAATGSSGATTVAATAHLAALCGIKLFATGGLGGVHRGARESWDVSADLAALSRAPVAVVCSGVKSILDVPATLEQLETLGVPVVGFRSRSFAGFYLTDSGCALDWSVEDEGEAAALIRALPGLGLGCGVVISNPLPPEEQLDPSLHERALRSGLEELARRGISGKEVTPFLLEHFRERTGGESLRANERLVVRNARLAARIARRLAAGR
What is the function of this protein?
Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil.  Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
What are the official names of this protein?
Pseudouridine-5'-phosphate glycosidase, PsiMP glycosidase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine-5'-phosphate glycosidase family.
Protein: PARB_MYCTO
Sequence: MTQPSRRKGGLGRGLAALIPTGPADGESGPPTLGPRMGSATADVVIGGPVPDTSVMGAIYREIPPSAIEANPRQPRQVFDEEALAELVHSIREFGLLQPIVVRSLAGSQTGVRYQIVMGERRWRAAQEAGLATIPAIVRETGDDNLLRDALLENIHRVQLNPLEEAAAYQQLLDEFGVTHDELAARIGRSRPLITNMIRLLKLPIPVQRRVAAGVLSAGHARALLSLEAGPEAQEELASRIVAEGLSVRATEETVTLANHEANRQAHHSDATTPAPPRRKPIQMPGLQDVAERLSTTFDTRVTVSLGKRKGKIVVEFGSVDDLARIVGLMTTDGRDKGLHRDAL
What is the function of this protein?
Involved in chromosome partition.  Localize to both poles of the predivisional cell following completion of DNA replication.  Binds to the DNA origin of replication (By similarity).
What are the official names of this protein?
Probable chromosome-partitioning protein ParB.
What is the protein family that this protein belongs to?
Belongs to the ParB family.
Protein: ALDH_PAENI
Sequence: MAIATIDPTTGITLKTFDAHTPEEVENRIARAEAAFRSLQNTSFEERARWMHKAADILESEADEVARLIATEMGKTLTTAKYEALKSATGMRHFADHAQRYLSPETPVPASEVNASNLHVQFDPLGVVLAVMPWNYPLWQAVRFAAPALMAGNTGLLKHASNVPQCALYLGDLFARGGFPEGAFQTLLVEGKDVIPLVDDARIRAVTLTGSVAAGSAIAEAAGRNIKRSVLELGGMDVFIVMPSADIEKAAAQAVIARLQNSGQSCIAAKRFYVHEDVYDRFEHLFVTGMAEAVAGDPLDESTSFGPLATERGRQDVHELVRDAREKGAAVQCGGEIPEGEGWYYPATVLTGVTEDMRIYREECFGPVACLYKVSSLQEAIALSNDSDFGLSSSVWTNDETEATEAARSIEAGGVFINGLTASFPAVPFGGLKDSGYGRELSAYGIREFVNIKTVWTS
What is the function of this protein?
Aldehyde dehydrogenase able to oxidize various aldehydes such as formaldehyde, glyceraldehyde, butyraldehyde, glutaraldehyde and benzaldehyde (in vitro).  Is likely involved in the oxidative D-xylose degradation pathway, catalyzing the oxidation step of 2-oxoglutarate semialdehyde to 2-oxoglutarate.  Is able to use both NAD(+) and NADP(+); however, shows a preference for NADP(+).  Does not display succinate semialdehyde dehydrogenase activity.
What are the official names of this protein?
Aldehyde dehydrogenase, NAD/NADP-dependent aldehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: ACPS_BREBN
Sequence: MIIGTGVDIVEIERIATLIKRQERAIKHFLTTDEQQLLHGKSETRQAEMVAGRFAAKEAGAKALGTGIGAVLSFLDMEILPNHLGKPVMTIKNEVYSKLDLDPTRVHIHVSISHSQSHAIAQVIVEER
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAL_FLAPJ
Sequence: MKFFIDTANLAQIKEAQALGVLDGVTTNPSLMAKEGITGKNNILKHYVDICNIVEGDVSAEVNAMDYDGMIREGEELAELHDQIVVKLPMTKEGIMACKYFSDRGIRTNVTLIFSAGQALLAAKAGATYCSPFIGRLDDISTDGLNLIQEIRDIYDNYGFETQILAASVRHTMHVVNCAKIGADVMTGPLSSILGLLKHPLTDIGIAQFIADFEKGNR
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEPF1_PLAF7
Sequence: MNEIKSESLLQTRPFKLGIEDIQNLGSSYFIENNEKLKKYNNEISSLKKELDILNEKMGKCTTTTKIVEPAKTPEFTFWYYELKEMKGFQDLVMYEVKKKKKHFKVLSHSCLKYLSNREKMKIKKQEEEEKRLKLYSKNISSYMDVFWKKIEKLVWEEKKRELQQTLNKKKEMRFKKFVKEAIKKIKDARHNNAHELFENKYVSMSSNNNSEIVNNNASSVDNGDKELKEDDLTDQEEEDYLLDEQMSSTDESENKEEEINMLDDEANLPIEELLKRMYGFKSGEDYINFMENEDDANEENVIETSHNDEKSGDNSIGEDDNNNDEKGGDNNIDEDDNNNDEKSGDNSIGEDDNNNDHKSGDNNIDEDDNNNDHKSEDNSIGEDDNNNDEKGGDNNIDENDNNSDHKSEDNNIDENDNNSDHQSDQEQFNHETKDDIIKNSSYEHIDNKNYYNKTGEDYKSDKENYSPTRFHNKLKKEKYDEYDTKLKIEKREEENKNYEKDEHEYESDNYDKEKINKKKELILLKNDIENDSDETSEHIKRDSRSSCQKQNCEKKRRIIKDEYNLRRTKIAKSKPSSDNNNSENDNNNDNNNDNNNDNNDDNNDDNNDDNNDDNNDDNNDDNNDDNNNEHKNDSDDNDDILTCNMDEKHLTKIPPIIKATLRDYQHAGLHWLLYLYKNNINGILADEMGLGKTLQCISLLSYLAYYFNIWGPHLVIVPTSILINWEIELKRFCPCFKILSYYGNQNERYKKRVGWFNKDSFHICISSYSTVVKDHLVFKRKRWKYIILDEAHNIKNFNTKRWNIILSLKRDNCLLITGTPLQNSLEELWSLLHFLMPNIFTSHLDFKEWFSDPLNLAIEKSKIHHSKELIDRLHTVIRPYILRRLKKNVEKEMPNKYEHIIKCKLTRRQQILYDEFINNKNVQNTLNTGNYIGLMNILIQLRKVCNHCDLFTNKYIQTPYYYMLSIRYFVPRFFILFEKNYYADFYLILFLHNEFTSLGGRDVTKETSPSSKSFDLAHILTKHNTNELYDNNHISELYDNNHISELYDNNHISELYDNNHISELYDNPMSHKNYKHNSNGYTYPNDPINNMNNNPSGFTKTSEQFGQIVSHERDNNYHMMDHNNMNNLLSKEMVNSLRNDDNSNNNFYKYSLTSNNNDSQTSIHDNKQCDYNKLCADTFNNINSIGNEEKRSLNVLNEQNNNNSKDNNNNIDNNNNIDNNNNIDNNNNIDNNNNIDNNNNNIDNNNNIDNHHNNNQHCNYNDNWPSDYPTNIINHRNAFLSILKLLNQSNPLNNDNNNNNNNNNGNNNIYNMNRYNSRNSRNSSLSNIFSSNTSKMNSFQLDFLYTNSFINQDALCKNSFFVNINIEDVHSYIYNSIYKEYIPKNILSFSDEFLTELNNNYDILSLYIDPYNRYKSYNEYLYKMKEEGTLTNQQSLGDINNKHIYHKSTSNENTHMKNRKTFIYKYNNMFKVINNDTQYQNIFTDDTNNSYYNSLEHNLWIKRNQIDERKKEEEEEQNKYYNVCMNNLYILRNERIPIFGKNFLDLIKKEFTKDKNIVYNYTNNVPIDYYSSVKEVWVEDICEKDNKKRKCKREKRWYKKIKKTNNPPEDSEVYRENSSDVEKYNCDVEKDNCDDEEKDNCDDEDMNSNLSSNVYGCIDISSQNFIHSRYHNPMMNMSYIIEFLFPNMEQFLKRHEKMIHNFTLINNPSVICKSHDIRINNNLLNYSNDKMNPIILQIKNATRVYHDAFLKQSIIFPLNKDISLGSGKLCALEKLLSKCKREGNKCLLFTQFIKMLDILEIFLNHLNYSFIRLDGSTKVEQRQKIVTKFNNDKSIFIFISSTRSGSIGINLTAANVVIFYDTDWNPSIDKQAMDRCHRIGQTKDVHVFRFVCEYTVEENIWKKQLQKRKLDNICINMGNFNNSNTHSKITDTDPTHNKDWFTNVDTIKEVFINKKNNDDDDDMYKDRLLHEQVENKDKMNVRFEKTLEHVEDKDDIRALNETKKETQNEISQNMQEFTTRNDFQDSYNLTSYCFNFLNENLTDSLKQQIDEMRMKIEIEMMNTGDENMSLSDLSNKSHNSE
What is the function of this protein?
Catalytic component of a chromatin remodeling complex.
What are the official names of this protein?
Probable ATP-dependent helicase PF08_0048.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLNH_ECOL6
Sequence: MKSVLKVSLAALTLAFAVSSHAADKKLVVATDTAFVPFEFKQGDKYVGFDVDLWAAIAKELKLDYELKPMDFSGIIPALQTKNVDLALAGITITDERKKAIDFSDGYYKSGLLVMVKANNNDVKSVKDLDGKVVAVKSGTGSVDYAKANIKTKDLRQFPNIDNAYMELGTNRADAVLHDTPNILYFIKTAGNGQFKAVGDSLEAQQYGIAFPKGSDELRDKVNGALKTLRENGTYNEIYKKWFGTEPK
What is the function of this protein?
Involved in a glutamine-transport system GlnHPQ.
What are the official names of this protein?
Glutamine-binding periplasmic protein, GlnBP.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 3 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y1164_OENOB
Sequence: MANKDQQDNDKYVTLTDEKGNESLYEILFTFHSDEYKKDYILFTPAGSDRITVEDPDQEVEIQAFSFDPTSGDSETDSDLYPIENDDEWNMVSEVLNTFVEDDSLRTDDKNDED
What are the official names of this protein?
UPF0473 protein OEOE_1164.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: RS12_THEVO
Sequence: MGNGLNAGRKLLENRKKFRWSDRDYKRRVLQLKRKSDPLEGAPQAKGIAIEKVGIEAKQPNSAIRKCVKVQLIKNGRQITAFAVGDGAINYIDEHDEVTVEGIGGRMGRSKGDIPGVRYKVVAVNGISLKELVKGRKEKTVR
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: MDM10_AJEDR
Sequence: MRDFMDYIQLAFYDASKWNRDNSYSQLTTTANALLDFSTPERLKVNLSSLSTPHFATTYTLGTVGLIDGSISYLFTTIPLHDTPSRSTLIPLRKLVPGYRQIYPPSLPPAFPAADGRDGDLAIGGTEGDLKKKATLLHATLHLPPPTTLTGSFLRRLSPTTQLSLAFCSSRAPASKSAPQATTDNALFGFKGLWNFGPDPRKQNQNGGDPAREPCRSLLSLLSAGGEVYYSPVSSVVGLSTGLRFTTLPAATENPHSTFPYTLTLTLTPLTGSMSTTYSLLASPNLAFSSRFGFNVYSWESEMVAGCELWRRSKKLHTLQRNSSPLFAVDDLTWARRKMGLQDAAVSVHPERDGLPGIQRDDHDMHHHPQRPHASDSVIKVRVDQSWNIRALWEGRVKELVVSAGIALGPKSRSSLSYASSLAASGPGAAGGLSSYGWKSVGVSVLYSS
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange.  MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex).  Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins.  Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins.  May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway.  Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 10, Mitochondrial inheritance component MDM10.
What is the protein family that this protein belongs to?
Belongs to the MDM10 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: CRVP1_NAJNA
Sequence: NVDFNSESTRRKKKQKEIVDLHNSLRRRVSPTA
What is the function of this protein?
Blocks contraction of smooth muscle elicited by high potassium-induced depolarization, but does not block caffeine-stimulated contraction.  May target voltage-gated calcium channels on smooth muscle (Cav) (By similarity).
What are the official names of this protein?
Cysteine-rich venom protein, CRVP, Cysteine-rich secretory protein 1, CRISP1, Cysteine-rich secretory protein 2, CRISP2, Najanajin.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: ORF3_HEVBU
Sequence: MGSRPCALGLFCCCSSCFCLCCPRHRPVSRLAAVVGGAAAVPAVVSGVTGLILSPSQSPIFIQPTPSPPMSPLRPGLDLVFANPPDHSAPLGVTRPSAPPLPHVVDLPQLGPRR
What is the function of this protein?
Small multifunctional phosphoprotein involved in virion morphogenesis, egress and counteracting host innate immunity.  Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway.  Acts also as a viroporin and forms ion conductive pores allowing viral particle release.  Impairs the generation of type I interferon by down-regulating host TLR3 and TLR7 as well as their downstream signaling pathways.  Down-regulates the phosphorylation of host IRF3 via the interaction with host SIRP-alpha, thereby inhibiting IFN-I expression.  Interacts with host microtubules.
What are the official names of this protein?
Protein ORF3, pORF3.
What is the protein family that this protein belongs to?
Belongs to the hepevirus ORF3 protein family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane. Host cytoplasm. Note=The N-terminal region seems to associate with the cytoskeleton probably via one of its hydrophobic regions.
Protein: PTFA_BACSU
Sequence: MISVIISGHGDFPIALKESSGMIFGEENNLIAVPFFKGEGIQTLQEKYHQALKDIPEEHEVLFLVDIFGGTPYNAAASFIAEDQRMDMAAGVNLPILLEVLSLREHLALKDLLNNLKAMSQQSFQVCSEHLEKVKTANQDTREDEL
What is the function of this protein?
LevD and LevE act as negative regulators of the levanase operon.  They may be involved in a PTS-mediated phosphorylation of a regulator.
What are the official names of this protein?
PTS system fructose-specific EIIA component, EIIA-Fru, Fructose-specific phosphotransferase enzyme IIA component, lev-PTS, p16.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_VIBC3
Sequence: MSNEEIKNKDEQLQQDAVETEAEVVGTDADIDWNQAADEIDEKEAKIAQLEAALLVSEERVKEQQDSVLRARAEVENMRRRSEQEVDKARKFALSRFAEELLPVIDNLERAIQAADGEVEAIKPLLEGVELTHKTFVDTIAKFGLKEINPHGEVFNPEFHQAMSIQESAEHEPNTVMFVMQKGYELNGRVLRPAMVMVSK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHED_STRM5
Sequence: MNASLRTDDVMRYQDARFKTIAAKLLPTQYLVVDDTTALTTTLGSCVAACLRDPVLKIGGMNHFLLPEGNAGDGAPARYGSYAMELLINDMLKRGAHRKRIEAKVFGGANVLKGFTSNPVGTRNAEFVRQYLQAEHIPIIAEDLCGIHPRKIWFFADTGRVVVQRLPHAHEAEVAATESAVRARLSKAPVTGGVELFE
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: RIBA_SHESR
Sequence: MSIKYVATSKLPTPWGVFAMHGFEDTETGKEHVALTFGTLNSDAPVLGRIHSECLTGDALFSLRCDCGFQLQTAMQNIAETGSGFILYLRQEGRGIGLLNKIRAYELQDKGANTVEANEQLGFPADMRKYDMIQPMLEQIGVKHVRLMTNNPRKVKAMKEIGIEVVERVPLQVGKNRYNEAYLKTKSTELGHMMSEYHFTDEE
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: DCA15_XENLA
Sequence: MAPSSKSERNSGAGSAGGGPGGTGGKRAVGRRREHVLKQLERVKISGQLSPRLFRKLPPRVCVSLKNIVDEDFLYAGHIFLGFSKCGRYVLSYTSSSGDDDFSFYIYHLYWWEFNVHSKLKLVRQVRLFQDEEIYSDLYLTVCEWPSDASKVIVFGFNTRSANGMLMNMMMMSDENHRDIYISTVAVPPRGRCAACQDASRAHPGDPSAQCLRHGFMLHTKYQVVYPFPTFQPAFQLKKDQVVLLNTSYSLVACAVSVHSAGDSSFCQILYDHTALPPAPPSSPGPWSPEAAPAFPSLGVEVVPAQPSGAPEPSPAIAKAKEFVADIFRRAKEAKGSPLEETRLPSSLGPSSSRCRPSLEPQAPSGEVVPRDSPPAAETTAPEPGYINYTKLHYVLQSGEGTEPEDEFEDDKISLPFVVTDLRGRNLRPMRERTDMQGQYLTVEQLTLDFEYVINEVIRHDATWGHQFCSFSDYDIVILEVCPETNQVLINIGLLLLAFPAPTEEGQLRPKTYHTSLKVAWDLNTGIFETVSVGDLTEVKGQTSGSVWSSYRKSCVDMVMKWLVPESSGRYVNRMTNEALHKGCSLKVLADSERYTWIVL
What is the function of this protein?
Substrate-recognition component of the DCX(DCAF15) complex, a cullin-4-RING E3 ubiquitin-protein ligase complex that mediates ubiquitination and degradation of target proteins.  The DCX(DCAF15) complex acts as a regulator of the natural killer (NK) cells effector functions.
What are the official names of this protein?
DDB1- and CUL4-associated factor 15.
Protein: YORC_BACSU
Sequence: MSNIISKEQDEAIKYFRNKLNLSDKDLYIPLINFELLRDKNEQYANILYELYKNDPYLFIRALKEGYVVNQPIAFDEAIVRFFNGEELAIVHKTTGRRYNVNVKMKQLPDGFSLQTMDMWLWSELV
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YorC.
Protein: HFQ_NEIMB
Sequence: MTAKGQMLQDPFLNALRKEHVPVSIYLVNGIKLQGQVESFDQYVVLLRNTSVTQMVYKHAISTIVPARSVNLQHENRPQAAPTSTLVQVETVQQPAE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: CYB6_CYAM1
Sequence: MSKVYDWFQERLSIQDIADDITSKYVPPHVNIFYCLGGMTLTCFLVQVATGFAMTFYYRPTVAEAFSSVEYMMTQVNFGWLIRSLHRWSASMMVLMMILHIFRVYLTGGFKKPRELTWITGVILGVLTVSFGVTGYSLPWDQVGYWACKIVTGVPEAIPVVGSSLVELLRGDVSVGQATLTRFYSLHTLVLPVLSLVFMLAHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ORRM1_MAIZE
Sequence: MDTALPSVLIGGGLSVSVSISTATKAGSQSISSHLSTSSLRLTARHRNRRRLPLLASSSESPPAQLAAASTESQSRSSRWVVVMDTPPAAAGGSGVSRAEAVDYYAATLAQVVGSEKEAQMRICEASWDGTYEFRCEIDEDASKELAKMPGVLSVQLDMGNKSEKDNHSLSLSTANLVSISDGASTSSSGKNEFWLVRMEKPGVEVVTKAQMVDHYTQILMKVLGNEQDAQVSIYHVSWDRDYGFCCHIDEECAKELADVPGVLSVQPDTNFGSDNKNYKGDDGVKSSEGTGAVDIKTKRLFVTGLSFYTSEKTLRAAFEPFGELVEVKIIMDRISKRSKGYAFVEYTTEEAGGAALKAMNGQIINGWMIVVDVAKTRSRDRLSGGSNQAFRPHYQAR
What is the function of this protein?
Involved in C-to-U editing of chloroplastic RNA.  Functions as major chloroplastic editing factor.  Controls a majority of the chloroplastic editing sites.
What are the official names of this protein?
Organelle RRM domain-containing protein 1, chloroplastic, ZmORRM1.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HIS7_SALPA
Sequence: MSQKYLFIDRDGTLISEPPSDFQVDRFDKLAFEPEVIPVLLKLQKAGFKLVMITNQDGLGTQSFPQADFDGPHNLMMQIFTSQGVCFDEVLICPHLPADDCDCRKPKVKLVERYLAEQAMDSANSYVIGDRATDIQLADNMGITGLRYHRETLNWTMIGEQLTKRDRYAHVVRNTKETQIDVSVWLDREGNSKINTGVGFFDHMLDQIATHGGFRMEITVKGDLYIDDHHTVEDTGLALGEALKLALGDKRGICRFGFVLPMDECLARCALDISGRPHLEYKAEFTYQRVGDLSTEMIEHFFRSLSYTMGVTLHLKTKGKNDHHRVESLFKAFGRTLRQAIRVEGDTLPSSKGVL
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisB.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.