PharMolix/UniProtQA huggingface dataset:
Protein: RL5_ACIBT
Sequence: MARLKARYNDELKAKLQEELSIKNVMEIPRITKITLNMGVGAAATDKKLLDGAVADMQLIAGQKPVVTLARKSIAGFKIRDGWPIGCKVTLRGDQMYEFLDRLISIAIPRIRDFRGFSAKSFDGRGNYSMGLKEQIVFPEIDFDKIDRIRGMDITITTTARTDDEGRALMRAFGFPFK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RHAD_YERPY
Sequence: MQAILSSWFIQGMIKATSDMWHKGWDERNGGNISLRLLAEEVEPYRRDFYQQPRKVELTQPAPELANSWFLVTGSGKFFRNVELNPAENLVLLQVSNDGMAYHIHWGLTQGGLPTSELAAHFQSHIVRMQVSGGTNRVIMHCHATNLIALSYVQKLENASFTRLLWEGSTECLVVFPDGIGIVPWMVPGTDGIGTQTAEQMREHSLVLWPFHGIFGSGPTLDDAFGLIDTAEKSAEIMVKVLSMGGKKQTISREQLIALAARFDVTPMAAALDA
What is the function of this protein?
Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
What are the official names of this protein?
Rhamnulose-1-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. RhaD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAD_MANSM
Sequence: MQNIINSWFVQGMIKATYDMWLKGWDERNGGNVSLRLLDDDVVSYKDEFYQNPRHVEITQNITALANQYFIVTGSGKFFRNVIIDPADTLAVIKVDEQGKGYYIMWGLVNGGVPTSELPAHLQSHIVRMKVSGGKDRVIMHCHATNLIALTYVLELDPKVITRELWEMSTECLVVFPDGVGVLPWMTPGKDEIGYATAQEMAQHPLVLWAFHGVFGTGPTLDDAFGLIDTAEKSAEILVKVLSMGGKRQTIQTDEFKLLAERFGVTPMDGVL
What is the function of this protein?
Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
What are the official names of this protein?
Rhamnulose-1-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. RhaD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_RUEPO
Sequence: MKTLVICSGGLDSVSLAHKVAAEHDLIGLISFDYGQRHRKELDFAARAATRLGVPHDLIDMRQIGAHLSGSALTDDVDVPDGHYAEDTMKITVVPNRNAIMLAIAFGIAAAKQADAVATAVHGGDHFIYPDCRPGFTQAFEAMQAQALDGYASVRLYTPFVHEPKSAIVTEGERHNTPFADTWSCYKGGEVHCGRCGTCVERREAFHLAGVADPTPYADPEFWRAAVEGR
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RS9_BURO0
Sequence: MIGNWNYGTGRRKSAVARVFIKAGKGDIIVNGKPIADYFSRETSLMIVRQPLELTNHGQTFDIKVNVNGGGETGQAGAVRHGITRALIDYDATLKPSLSSAGFVTRDAREVERKKVGLRKARRAKQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: KGUA_CHLTE
Sequence: MSAEQVLDQGRLIVFSAPSGTGKSTVAKLVMERLGSLEFSVSATTRQMRAGERDGVDYHFLSREEFEKKIAENGFIEHEFFFGNFYGTLLDKTIDAIKAGHNLLFDLDVKGALNLKRIFGDQALLVFLKPPSMEELARRLQARDSESAEALKSRLERAEMELSHAGEFDFVVVNDDLGRTVDAVATRIAEFLPQP
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_PSEPG
Sequence: MSLTNEQIIEAIGQKTVLEVVELIKAMEETFGVTAAVAAAGPAAAAAVVEEQTEFNVVLVEAGDKKVNVIKAVRELTGLGLKEAKEKVDGAPQVVAEGVSKEAAEDAKKKLEEAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: COF_KLEP3
Sequence: MAKLAAFDMDGTLLMPDHRLGEQTLTALKRLRERNITLTFATGRHVLEMHHVIGEFSLDAFLITGNGTRIHSLEGEELYRQDLAPEAAEAVLHSKWDTQASMHVFNDGGWFTGQARPELLKAHAFSGFHYQLCDPKRMPAHHVTKICFCGDHDDLRRLRIQLNETLGDRAFLCFSAMDCLEVLPVGCNKGAALAVLSQHLGFTLQECMAFGDAMNDREMLGSVGRGFIMGNAMPQLKAELPHLQVIGDCRHQAVSHFLTHWLDNPDLPYSPE
What is the function of this protein?
Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).
What are the official names of this protein?
HMP-PP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family.
Protein: ISDB_STAAC
Sequence: MNKQQKEFKSFYSIRKSSLGVASVAISTLLLLMSNGEAQAAAEETGGTNTEAQPKTEAVASPTTTSEKAPETKPVANAVSVSNKEVEAPTSETKEAKEVKEVKAPKETKEVKPAAKATNNTYPILNQELREAIKNPAIKDKDHSAPNSRPIDFEMKKKDGTQQFYHYASSVKPARVIFTDSKPEIELGLQSGQFWRKFEVYEGDKKLPIKLVSYDTVKDYAYIRFSVSNGTKAVKIVSSTHFNNKEEKYDYTLMEFAQPIYNSADKFKTEEDYKAEKLLAPYKKAKTLERQVYELNKIQDKLPEKLKAEYKKKLEDTKKALDEQVKSAITEFQNVQPTNEKMTDLQDTKYVVYESVENNESMMDTFVKHPIKTGMLNGKKYMVMETTNDDYWKDFMVEGQRVRTISKDAKNNTRTIIFPYVEGKTLYDAIVKVHVKTIDYDGQYHVRIVDKEAFTKANTDKSNKKEQQDNSAKKEATPATPSKPTPSPVEKESQKQDSQKDDNKQLPSVEKENDASSESGKDKTPATKPTKGEVESSSTTPTKVVSTTQNVAKPTTASSKTTKDVVQTSAGSSEAKDSAPLQKANIKNTNDGHTQSQNNKNTQENKAKSLPQTGEESNKDMTLPLMALLALSSIVAFVLPRKRKN
What is the function of this protein?
Cell wall-anchored surface receptor that extracts heme from oxidized metHb to enable growth on hemoglobin as a sole iron source.  Rapidly extracts heme from hemoglobin and transfers it to IsdA or IsdC, which then relays it to the membrane transporter/IsdEF for internalization.  Promotes also resistance to hydrogen peroxide and killing by neutrophils.
What are the official names of this protein?
Iron-regulated surface determinant protein B, Fur-regulated protein B, Staphylococcal iron-regulated protein H, Staphylococcus aureus surface protein J.
What is the protein family that this protein belongs to?
Belongs to the IsdB family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Anchored to the cell wall by sortase A.
Protein: GCS2_HALS3
Sequence: MDVGSPEAFSESGTLGVEEEFFVVDEHGVPTAGSDELVYEGEPPEPIAGRLDHELFKFVVETQTPTLNGVAEAPAAIREVRAALVAYASEHGLRIAGAGLHPGARWREHEHAEKPRYRSQLDRIQYPQHRNTTAGLHIHVGVDDPDKAVWVSNRMRWHMPVLLALSANSPYWNGFDTGLASARAKIFEGLPNTGLPTAFESYAAFQAFERRMVEHGGIEDRGELWYDVRPHSGHGTVEVRAPDAQADPAVVDAFVEYAHALVTEYAQRYDDHPDPFSVTGLRRELLDANKWRAMRDGHDASFVARETQGAVDLGTVVDRECDRLGVSGIRDVYDDVSGAQQQRRILDTHGEKRLYNHLSL
What is the function of this protein?
Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC), the main low-molecular-weight thiol compound instead of glutathione in halophilic archaea.
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-glutamylcysteine synthetase, GCS, Gamma-GCS.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: BIOB_KLEP3
Sequence: MAHRARWTMSQVTELFNKPLIDLLFEAQQIHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSARYKTGLETERLMEVEQVLESARQAKNAGSTRFCMGAAWKNPNDRDMPYLEQMVKGVKALGLESCMTLGTLTDSQAQRLAGAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLDKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAIARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGINPQQTAVLEGDNEQQQRLEQALLTPDTEEYYNAAAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: YRF16_YEAST
Sequence: MEIENEQICTCIAQILHLLNSLIITFLDDDKTETGQSFVYIDGFLVKKHNNQHTIVNFETYKNKMKVSDRRKFEKANFDEFESALNNKNDLVHCPSITLFESIPTEVRSFYEDEKSGLIKVVKFRTGAMDRKRSFEKIVVSVMVGKNVQKFLTFVEDEPDFQGGPIPSKYLIPKKINLMVYTLFQVHTLKFNRKDYDTLSLFYLNRGYYNELSFRVLERCYEIASARPNDSSTMRTFTDFVSGTPIVRGLQKSTIRKYGYNLAPYMFLLLHVDELSIFSAYQASLPGEKKVDTERLKRDLCPRKPTEIKYFSQICNDMMNKKDRLGDILHIILRACALNFGAGPRGGAGDEEDRSITNEEPIIPSVDEHGLKVCKLRSPNTPRRLRKTLDAVKALLVSSCACTARDLDIFDDNNGVAMWKWIKILYHEVAQETALKDSYRITLVPSSDGVSVCGKLFNREYVRGFYFACKAQFDNLWEELNDCFYMPTVVDIASLILRNREVLFREPKRGIDEYLENDSFLQMIPVKYREIVLPKLRRDTNKMTAALKNKVTVAIDELTVPLMWMIHFAVGYPYRYPELQLLAFAGPQRNVYVDDTTRRIQLYTDYNKNGSSEPRLKTLDGLTSDYVFYFVTVLRQMQICALGNSYDAFNHDPWMDVVGFEDPDQVTNRDISRIVLYSYMFLNTAKGCLVEYATFRQYMRELPKNAPQKLNFREMRQGLIALGRHCVGSRFETDLYESATSELMANHSVQTGRNIYGVDSFSLTSVSGTTATLLQERASERWIQWLGLESDYHCSFSSTRNAEDVVAGEAASSDHHQKISRVTRKRPREPKSTNDILVAGQKLFGSSFEFRDLHQLRLCHEIYMADTPSVAVQAPPGYGKTELFHLPLIALASKGDVKYVSFLFVPYTVLLANCMIRLSRCGCLNVAPVRNFIEEGCDGVTDLYVGIYDDLASTNFTDRIAAWENIVECTFRTNNVKLGYLIVDEFHNFETEVYRQSQFGGITNLDFDAFEKAIFLSGTAPEAVADAALQRIGLTGLAKKSMDINELKRSEDLSRGLSSYPTRMFNLIKEKSEVPLGHVHKIWKKVESQPEEALKLLLALFEIEPESKAIVVASTTNEVEELACSWRKYFRVVWIHGKLGAAEKVSRTKEFVTDGSMRVLIGTKLVTEGIDIKQLMMVIMLDNRLNIIELIQGVGRLRDGGLCYLLSRKNSWAARNRKGELPPIKEGCITEQVREFYGLESKKGKKGQHVGCCGSRTDLSADTVELIERMDRLAEKQATASMSIVALPSSFQESNSSDRCRKYCSSDEDSDTCIHGSANASTNATTNSSTNATTTASTNVRTSATTTASINVRTSATTTESTNSSTNATTTASTNVRTSATTTASINVRTSATTTESTNSNTSATTTESTDSNTSATTTESTDSNTSATTTASTNSSTNATTTASTNSSTNATTTESTNASAKEDANKDGNAEDNRFHPVTDINKESYKRKGSQMVLLERKKLKAQFPNTSENMNVLQFLGFRSDEIKHLFLYGIDVYFCPEGVFTQYGLCKGCQKMFELCVCWAGQKVSYRRMAWEALAVERMLRNDEEYKEYLEDIEPYHGDPVGYLKFFSVKRGEIYSQIQRNYAWYLAITRRRETISVLDSTRGKQGSQVFRMSGRQIKELYYKVWSNLRESKTEVLQYFLNWDEKKCREEWEAKDDTVFVEALEKVGVFQRLRSMTSAGLQGPQYVKLQFSRHHRQLRSRYELSLGMHLRDQLALGVTPSKVPHWTAFLSMLIGLFCNKTFRQKLEYLLEQISEVWLLPHWLDLANVEVLAADNTRVPLYMLMVAVHKELDSDDVPDGRFDILLCRDSSREVGE
What is the function of this protein?
Catalyzes DNA unwinding and is involved in telomerase-independent telomere maintenance.
What are the official names of this protein?
Y' element ATP-dependent helicase protein 1 copy 6.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Yeast subtelomeric Y' repeat subfamily.
Protein: XYLA_THETC
Sequence: MSKYFEKVSKIKYEGPKSNNPYAFKFYNPEEVIDGKTMEEHLRFSIAYWHTFTADGTDQFGKATMQRPWNHLTDPMDIAKARVEAAFEFFDKINAPFFCFHDRDIAPEGDTLRETNKNLDIIVAMIKDYLKTSKTKVLWGTANLFSNPRFVHGASTSCNADVFAYSAAQVKKALEITKELGGQNYVFWGGREGYETLLNTDMELELDNFARFLHMAVDYAKEIGFEGQFLIEPKPKEPTKHQYDFDVANVLAFLRKYDLDKYFKVNIEANHATLAAHDFQHELRYARINGVLGSIDANTGDMLLGWDTDQFPTDIRMTTLAMYEVIKMGGFDKGGLNFDAKVRRASFEPEDLFLGHIAGMDAFAKGFKVAYKLVKDGVFDKFIEERYASYKDGIGADIVSGKADFKSLEKYALEHSEIVNKSGRQEMLESILNQYLFTE
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_BIFLO
Sequence: MIGMLTGRVESVETDTALIDVGGVGYEVRMSATDLSRLHAGQDTRVFTYMNLSQDAITLHGFLDRDAKKTFLQLIKVSGIGPKVAQSLLSTLTPSQLAHAIADNDATALAKAPGLGKKGAQKIILELKGSIDLSQIEGASAQAATSKSPVDTGTEQVVEGLISLGWRQQDAQQAVAEACAENDIPTPLATDDVPRVLRLALALMDRGR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: URED_ALCBS
Sequence: MSVEKPVAAGRQNSKATGRHKGWQAKLHMQLECAITGRGMKTVMAELHHYGPLRVQRPFYPEQDTAHIYLLHPPGGVVGGDGLDISITASSQAHGLLTTPGATKFYRSAGQTAHVSQTLTVQAGGTLEWFPQENIFFPGARVQMDTRIDLHGDAHFMGWEISCLGRPVNSEVFHEGKIDARFRISRDRKPLLIERLKVDQPSHLNAASGLRNFPMQAIFVATGSNEELLEQARECIEKQATDMPCGLTLIDDILVMRVLGTRCEKIQALMLPVWQLLRQATLNKPAVIPRIWNT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COOF_RHORU
Sequence: MPPIKENVIIYANPDHCLSCHSCELACAVAHSGGHDMIEAIAANLPLHARNKVVSVDGTAMPMQCRQCEDAPCTFACPTGACRQADGQVQIVEQHCIGCKLCVMVCPFGAITVRSETVVEQGACTNRGVAKKCDLCVDWRASTGKTAPACVEACPTKAIRMVDLDAYRIALREARAREIAKSHRHMRVQF
What is the function of this protein?
The carbon monoxide dehydrogenase (CODH) oxidizes carbon monoxide coupled, via CooF, to the reduction of a hydrogen cation by a hydrogenase (probably CooH).  CooF is required in stoichiometric amounts in vitro for anchoring CODH to the membrane as well as for conveying the electrons to the hydrogenase.
What are the official names of this protein?
Iron-sulfur protein.
Protein: MEND_ENTFA
Sequence: MNHQETMTDYLMAFIEGLKNSGVEQAVISPGSRSTPLALLLHRETAIQTFVDVDERSAAFFALGLSKASQKPVVLLCTSGTAAANYYPAICEANISHVPLVVLTTDRPHELRQVGAPQAMDQLQMYQNHVKLFVEMALPEATEEMLNYAYWQGAKGAAFAQQTPAAPVHLNFPLREPLLPDLERKTKSSQQTALFAGQSILSTEQVQQLADQWYQKNGVLVVGGSHTEEEATLFIQLAEALQWPLLADPLANIVTHGQNSEVVIAHSDLFLNVATLPQEPEVVVRFGSLPISKNIMLWLKRLATTETAFYFVDENGQWQEQLKKSQTVIQAKETTFVEQLLTVVKPTEATWLAQWLLLEKTVSEVLLETLNATELNETTASLAVHQTMKENGQLFVSNSMAIRYLDRFMDSRPYRMFGNRGINGIDGIVSTALGMSAIAPTQQNVLLIGDLALYHDMNGLFLAKRYQLPLTIVLLNNNGGGIFSFLSQRTLREDDFEPLFGTPLDLDFSLVAELYGASYQEVKTIAELKQILQAAAEEPQFQVIEVKGNRQENVHLYESILAEIGRRVERQGISWNG
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: RL20_HAHCH
Sequence: MPRVKRGVTARRRHKKVLNQAKGYYGARSRVFRVAKQAVIKAGQYAYRDRRQRKRQFRALWIARINAGARDNGLSYSRLIAGLKRANVEIDRKVLADLAMNEKAAFAAVVQKAKEALA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: BRWD3_HUMAN
Sequence: MAAAPTQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFEDLVAANAHIPPDYLLKICERIGPLLDKEIPQSVPGVQTLLGVGRQSLLRDAKDCKSTLWNGSAFAALHRGRPPELPVNYVKPPNVVNITSARQLTGCSRFGHIFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQEWKSIVLDMATKMTGNNLPSGEDKITKLKVTMVAWDRYDTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFGCSKYYEKIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENCKDEQLIPQLGYVANGDGEVVEQVIGQQTNDQDESILDGIIRELQREQDLRLINEGDVPHLPVNRAYSVNGALRSPNMDISSSPNIRLRRHSSQIEGVRQMHNNAPRSQMATERDLMAWSRRVVVNELNNGVSRVQEECRTAKGDIEISLYTVEKKKKPSYTTQRNDYEPSCGRSLRRTQRKRQHTYQTRSNIEHNSQASCQNSGVQEDSDSSSEEDETVGTSDASVEDPVVEWQSESSSSDSSSEYSDWTADAGINLQPPKRQTRQTTRKICSSSDEENLKSLEERQKKPKQTRKKKGGLVSIAGEPNEEWFAPQWILDTIPRRSPFVPQMGDELIYFRQGHEAYVRAVRKSKIYSVNLQKQPWNKMDLREQEFVKIVGIKYEVGPPTLCCLKLAFLDPISGKMTGESFSIKYHDMPDVIDFLVLHQFYNEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQPEYPDSSFQCYSVHWDNNEREKMSPWDMEPIPEGTAFPDEVGAGVPVSQEELTALLYKPQEGEWGAHSRDEECERVIQGINHLLSLDFASPFAVPVDLSAYPLYCTVVAYPTDLNTIRRRLENRFYRRISALMWEVRYIEHNARTFNEPDSPIVKAAKIVTDVLLRFIGDQSCTDILDTYNKIKAEERNSTDAEEDTEIVDLDSDGPGTSSGRKVKCRGRRQSLKCNPDAWKKQCKELLSLIYEREDSEPFRQPADLLSYPGHQEQEGESSESVVPERQQDSSLSEDYQDVIDTPVDFSTVKETLEAGNYGSPLEFYKDVRQIFNNSKAYTSNKKSRIYSMMLRLSALFESHIKNIISEYKSAIQSQKRRRPRYRKRLRSSSSSLSSSGAPSPKGKQKQMKLQPKNDQNTSVSHARTSSPFSSPVSDAAEGLSLYLLDDEPDGPFSSSSFGGYSRSGNSHDPGKAKSFRNRVLPVKQDHSLDGPLTNGDGREPRTGIKRKLLSASEEDENMGGEDKEKKETKEKSHLSTSESGELGSSLSSESTCGSDSDSESTSRTDQDYVDGDHDYSKFIQTRPKRKLRKQHGNGKRNWKTRGTGGRGRWGRWGRWSRGGRGRGGRGRGSRGRGGGGTRGRGRGRGGRGASRGATRAKRARIADDEFDTMFSGRFSRLPRIKTRNQGRRTVLYNDDSDNDNFVSTEDPLNLGTSRSGRVRKMTEKARVSHLMGWNY
What is the function of this protein?
Plays a role in the regulation of cell morphology and cytoskeletal organization.  Required in the control of cell shape.
What are the official names of this protein?
Bromodomain and WD repeat-containing protein 3.
Protein: VE1_BPV3
Sequence: MDPNLKGITGQSFLDDQAECSESDNSEQGCEESLSDLSDLIDNAECEQGNSAELFAQQEAFAFQEHIRTTKRKLKLSFRNPLQCITSQSNRSPGRAAPKRRVLDDSGYNEDILAEVAQVDENGGSEGYGSLASQSLSGQSQKNGKNRVNNGNKENIDCTRLLAASSHRAVQLAIFKEKFGISLNSLTRIFKNDKTCCSNWVGVVFGAREELLAASQTILQRVCDSIMLLTHTCKLGFMGLYLLEFKNAKSRDTVRHLFQQILQVENNDMLLEPPKIKSLPAATFWWKLRHSSAAFLFGNLPDWIARQTSITHQIQEDQPFDLSAMVQWAYDHNFVDEAQIAYYYARLASEDSNAAAFLRCNNQVKHVKECAQMTRYYKTAEMREMSMSKWIKKCLNEIEGTGDWKQIINFIKYQNINFLSFLACFRDLLHSVPKRNCLVIVGPPNTGKSMFVMSLMRTLKGRVLSFVNSKSHFWLQPLNAAKIAILDDATRPTWSYIDTYLRNGLDGTPVSLDMKHRAPMQICFPPLIITTNVDVAKDPTFVYLHSRLMSFEFANAFPLDENGKPALILNELSWKSFFERLWNQLDLTEPEDEDDGDPPSPFRCSARAAARDL
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RSSA_AEDAE
Sequence: MSGNLDILALKDDDVTKMLAATTHVGSTSVNFQMESYVYKRRPDGVHIINLGRTWEKLLLAARCIASIEYPGEVFAISSRPYGQRAVLKFAHYTEATPTAGRFTPGAFTNQIQPAFREPRLLIVTDPLTDHQPVTEASYVNIPVIAFCNTDSPLKFVDIAIPCNNKSPHSIGLMWWLLAREVLRLRGKITHDKWDIKPDLFFYRDPEEAEKEQAALEAAPAAKDLYPEEPIVVDETNWAGEDAALPAVAAAPAAVAAAPAALPQLVQADDWNEDETQTAGSWGGGGGF
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein SA.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_BIFLO
Sequence: MAKYTNDELLEAFGEMTLVELSEFVKAFEEKFDVEAAAPVAAVAAVAGAAAPAEEEKDEFDVILSAVGDKKIQVIKAVRAITNLGLAEAKALVDGAPKAVLEKAKKEDAEKAKAQLEEAGASVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: ARCA_DINSH
Sequence: MTAHKLGVHSETGTLRQVIICRPGLAHRRLTPENCEELLFDDVFWVKQAKQDHEAFGAAMTQEGVEVLETGALLGETLEIPEARKWVLDHRISANDVGVGMRKDLRDWMDELPGTELATWLIGGLTVGDVPFEATSMFGAYLGRHGFILPPLPNFLFTRDNSSWVYGGVTLNPMYWQARRPETLLTAAIYRYHPKFAGKVHEIWADPLKNHGLATLEGGDVMPVGNGLVLVGMGERTSPQGVGLMAQALFGEGRATRVIACQMPKSRAAMHLDTVFTFCGDNIVTSFKEVADEMTCYDLHPGEGDKPLDMRHDTRPMFEVVAEAMGFKKLNVVPTGGSDPFEQSREQWNDGNNVLALRPGVVMGYDRNDDTNAALRAEGIKVIELPGAELGRGRGGSRCMSCPTIRDAV
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_DROME
Sequence: MSDHFNFNEAFNSQTMRGRANVAKATWASLGLVYVLVKMHRRNTKRRETKLYCKGCQQAMLHG
What are the official names of this protein?
Putative 60S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: KV5AI_MOUSE
Sequence: DVQMIQSPSSLSASLGDIVTMTCQASQGTNINLNWFQQKPGKAPKLLIYGASILEAGVPSRFSGRRYGTDFTLTISSLEDEDMATYFCLQHSYLPYTFGGGTKLEKKR
What are the official names of this protein?
Ig kappa chain V-V region EPC 109.
Protein: PSD_SALAR
Sequence: MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKYYKVDMTETQKPDTASYRTFNDFFVRPLRDDVRPLNTDPNILVMPADGVISQLGRIEEDKILQAKGHNYSLEALLAGNYLMADKFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYVPGELFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTITPPREGIIKRWTWPAGENEDSVALLKGQEMGRFKLGSTVINLFAPGKVDLIESLANLSVTKIGQPLATSTEAFVAPEVEPVPLPEEEIKAEHDASPLVDDKKDET
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GLGA_THISH
Sequence: MRILFASSEVHPLIKTGGLADVSASLPQALKRLRQDVRVVMPAYGSVLDKAGDLEQVTTLQLPGFPGDTVTLLSGTLPGSRVPLWLVDAPRLFRRAGDPYRAPDGHDWQDNYLRFGLFARLIEHLALDRAGLDWRPDVVHCNDWQAGLAPLMLSMHESRPATVFTIHNLAYQGLFPRHAFDALNLPPQLWHYQGLEFHGKLSFIKGGIGFADHITTVSPSYAREILTPQQGFGLDGLLNHRAGVLTGILNGVDYREWDPGKDRHLVARYSADDLSGKARCKAALQHHFKLPCHSGIPLLGHVGRMVAQKGVDLLLKAAEPLLAAGEAQLVVVGSGDATLEQTARSLAERYPEHMGLHIGYSEPLAHQLEAGADIFVMPSRFEPCGLNQMYSLRYGTVPVVRNTGGLADTVVDADPAHLAARDATGIQFDEATPQALADALARALALYHDPACWKRLMQAGMAQDFSWGRSAEAYLDLYKDLVS
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: CADC_STAAU
Sequence: MKKKDTCEIFCYDEEKVNRIQGDLQTVDISGVSQILKAIADENRAKITYALCQDEELCVCDIANILGVTIANASHHLRTLYKQGVVNFRKEGKLALYSLGDEHIRQIMMIALAHKKEVKVNV
What is the function of this protein?
Metal-binding repressor for the cad operon.  Involved in resistance to heavy metals, such as cadmium, bismuth, zinc or lead.  Binds 2 metal ions per subunit.  Metal binding to the N-terminal regulatory site causes the repressor to dissociate from the DNA.
What are the official names of this protein?
Cadmium resistance transcriptional regulatory protein CadC, Cadmium efflux system accessory protein.
Protein: GCH1_ECO57
Sequence: MPSLSKEAALVHEALVARGLETPLRPPVHEMDNETRKSLIAGHMTEIMQLLNLDLADDSLMETPHRIAKMYVDEIFSGLDYANFPKITLIENKMKVDEMVTVRDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQILIALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRHEFLRAVRHHN
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.