PharMolix/UniProtQA huggingface dataset:
Protein: UNG_STRA3
Sequence: MKHSSWHDLIKRELPNHYYNKINTFMDAVYESGIVYPPRDKVFNAIQITPLENVKVVIIGQDPYHGPQQAQGLSFSVPDNLPAPPSLQNILKELAEDIGSRSHHDLTSWAQQGVLLLNACLTVPEHQANGHAGLIWEPFTDAVIKVVNQKETPVVFILWGGYARKKKSLIDNPIHHIIESPHPSPLSAYRGFFGSRPFSRTNHFLEEEGINEIDWLN
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCNA_RAT
Sequence: MFEARLIQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVSIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSADVPLVVEYKIADMGHLKYYLAPKIEDEEGS
What is the function of this protein?
Auxiliary protein of DNA polymerase delta and epsilon, is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.  Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities.  Has to be loaded onto DNA in order to be able to stimulate APEX2.  Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways.  Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion (By similarity).
What are the official names of this protein?
Proliferating cell nuclear antigen, PCNA, Cyclin.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
What are the subcellular locations of this protein?
Nucleus. Note=Forms nuclear foci representing sites of ongoing DNA replication and vary in morphology and number during S phase. Together with APEX2, is redistributed in discrete nuclear foci in presence of oxidative DNA damaging agents. Colocalizes with CREBBP, EP300 and POLD1 to sites of DNA damage (By similarity).
Protein: MFS55_MYCTF
Sequence: MRAGRRVAISAGSLAVLLGALDTYVVVTIMRDIMNSVGIPINQLHRITWIVTMYLLGYIAAMPLLGRASDRFGRKLMLQVSLAGFIIGSVVTALAGHFGDFHMLIAGRTIQGVASGALLPITLALGADLWSQRNRAGVLGGIGAAQELGSVLGPLYGIFIVWLLHDWRDVFWINVPLTAIAMVMIHFSLPSHDRSTEPERVDLVGGLLLALALGLAVIGLYNPNPDGKHVLPDYGAPLLVGALVAAVAFFGWERFARTRLIDPAGVHFRPFLSALGASVAAGAALMVTLVDVELFGQGVLQMDQAQAAGMLLWFLIALPIGAVTGGWIATRAGDRAVAFAGLLIAAYGYWLISHWPVDLLADRHNILGLFTVPAMHTDLVVAGLGLGLVIGPLSSATLRVVPSAQHGIASAAVVVARMTGMLIGVAALSAWGLYRFNQILAGLSAAIPPNASLLERAAAIGARYQQAFALMYGEIFTITAIVCVFGAVLGLLISGRKEHADEPEVQEQPTLAPQVEPL
What is the function of this protein?
In association with lipoprotein LprG probably transports triacylglycerides (TAG) across the inner cell membrane into the periplasm; TAG probably regulates lipid metabolism and growth regulation.  May be an efflux transporter and involved in maintaining correct cell wall permeability.  Probably required with LprG for normal surface localization of lipoarabinomannan (LAM).
What are the official names of this protein?
Probable triacylglyceride transporter TBFG_11439, MFS-type drug efflux transporter P55.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL21_PECAS
Sequence: MYAVFQSGGKQHRVSEGQTVRLEKLDIATGEAVEFDLVLMVANGEEIKIGVPYVDGGKIKAEVVAHGRGEKVKIVKFRRRKHYRKQAGHRQWFTDVKITGISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: GUN1_ARATH
Sequence: MALYLSSSRLITFLSFILLLSNGFSSSSSRPSIHHRHHLDNHNYKDALSKSILFFEGQRSGKLPPNQRMTWRSNSGLSDGSALNVDLVGGYYDAGDNMKFGFPMAFTTTMLSWSLIEFGGLMKSELPNAKDAIRWATDFLLKATSHPDTIYVQVGDPNMDHACWERPEDMDTPRSVFKVDKNNPGSDIAGEIAAALAAASIVFRKCDPSYSNHLLQRAITVFTFADKYRGPYSAGLAPEVCPFYCSYSGYQDELLWGAAWLQKATNNPTYLNYIKANGQILGADEFDNMFSWDNKHVGARILLSKEFLIQKVKSLEEYKEHADSFICSVLPGASSSQYTPGGLLFKMGESNMQYVTSTSFLLLTYAKYLTSARTVAYCGGSVVTPARLRSIAKKQVDYLLGGNPLKMSYMVGYGLKYPRRIHHRGSSLPSVAVHPTRIQCHDGFSLFTSQSPNPNDLVGAVVGGPDQNDQFPDERSDYGRSEPATYINAPLVGALAYLARS
What are the official names of this protein?
Endoglucanase 1, Cellulase 2, AtCEL2, Endo-1,4-beta glucanase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 9 (cellulase E) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PULA_STRPN
Sequence: MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISSDESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPGNANASLEKTEEKPAASPADPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDSKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDLFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMTKRLLIDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEVLADENQAGPVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSKPEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSVKEAVRNESVENSSKENIPATPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNKKEN
What is the function of this protein?
Virulence factor (By similarity).  Involved in the degradation of glycogen of the mammalian host cells (PubMed:21565699).  Hydrolyzes the alpha-1,6-branchpoints of glycogen (PubMed:20497336, PubMed:21565699).  Hydrolyzes pullulan.  Does not hydrolyze dextran (PubMed:20497336).  Binds to mouse lung alveolar type II cells that are rich in glycogen stores.  Is an alpha-glucan-specific carbohydrate-binding protein, which binds to amylose (pure alpha-(1,4)-linked glucose), amylopectin (alpha-(1,4)-linked glucose with alpha-(1,6) branch points), pullulan (linear polymer of mixed alpha-(1,4)- and alpha-(1,6)-linked glucose) and glycogen (similar to amylopectin with more frequent alpha-(1,6) branch points) in vitro.  Does not bind to dextran (a linear polymer of alpha-(1,6)-linked glucose) (PubMed:17187076).
What are the official names of this protein?
Pullulanase A, Alpha-dextrin endo-1,6-alpha-glucosidase, Pullulan 6-glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Cell surface. Note=Localizes to cytoplasm in the lung alveolar type II cells of the mouse and human hosts.
Protein: OBG_LACCB
Sequence: MFVDQVQVEVQAGKGGDGMVAFRREKFVPFGGPAGGDGGHGGSIILYVDEGLRTLMDFRYQRHFKASAGGNGQGKQMYGRAAEDRRIAVPAGTTVTDADTGEVLGDLTEPGQTLVVAKGGRGGRGNMHFVSPKNTAPEISENGEPGEHRFIKLELKVLADVGLVGFPSVGKSTLLSVVTQAKPKIAAYQFTTLVPNLGMVQLDDGTDFVMADLPGLIEGASQGVGLGIQFLRHVERTRVLLHLVEMDPDNGREPLDDYDQIRKELGAYDDNILKRPELVVATKMDLPGAAERFADFKAALLARGVAADHIFEISSLTHRGVTPLMHKTAEVLKTAPHFEPEQAAVKTADYKYQPEPALKVTRDSDGTFVLTGDKIERAFKMANLDHEDGAMRFARQLRSMGVDDALRDAGAESGDLVAIDDFTFEFVE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_UREU1
Sequence: MDRIKAKINELKQKLDQWNYEYYVLDDPSVPDHVYDQAMRELIELENAYPQFKTNNSPSVRVGGFVSEKFNKVKHKRPMLSLSNAFDANDLRKFDQDNQNASVDLKGYVVEPKIDGLSISIIYKNAKLHQAITRGDGVNGEDVTSNILTIKDIPHYIDQKYKDYEIEVRGEVYMAFHDFYEMNDNLEESDKKFANPRNAAAGTLRSLDNSIVAERKLSAFMYYLVNAQELGIKTHYESIQFLKDNKFKVSDLIVKVDTIDEVINQIDRYTKVRNDLSYMIDGIVIKINNLEVYDEIGYTSKFPKWAIAYKFPANVVSSQLLEIINDVGRTGKISYVAKIKPILLDGSIVEYATLHNFDFIKEKDIRINDEIKIYKAGDVIPYVDGVDLSKRLANSVPYESITNCPSCQSVLVRENDEVDQRCLNIYGCKKINIEKIVYFVSRNCMNIEGMSDAIINKFYDANLIKNVADLYYLQKHKEFILASDFKIKDKSFSNLINSINNSKTRSLEFLLTAFGIRHVGPNLAKKLAKQFKTMTTLMHANFGELTNVDACGEKAALSLINWFNDDHNVSLVNQLQQVGVNMEYIDDFIYDDNINIIDEYKNKTFVITGSFSISRDEIKTILEKYYHAKVKNSVSKKTDYVLAGIEAGTKLEKAKLLGVKIIENEFWKKDNNF
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RUTD_ECODH
Sequence: MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVCYDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIEHYAVVGHALGALVGMQLALDYPASVTVLISVNGWLRINAHTRRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPTACSSELHAALPDSQKMVMPYGGHACNVTDPETFNALLLNGLASLLHHREAAL
What is the function of this protein?
Involved in pyrimidine catabolism.  May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.
What are the official names of this protein?
Putative carbamate hydrolase RutD, Aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
Protein: Y1201_PASMU
Sequence: MSKKDGYLEFFSYFNISEEKFINFAKESIIFIKQEKAKQEWDILKSKILNEKENVYVRNFGRNGQGGHLYQEVYKQLFLANIIVDPSNNNYPTKLLEKSVGLVKNKNLYNYQVSHIFGLTKNPYAFCAPWNIVFIPKILDPFTGHESKGEITEKITAMYRRLMWDKYEDLISDYNKIMEKYREVIKSEIEKYKALSKRKNDIYSRFIESVNIEFNVIEKI
What are the official names of this protein?
Uncharacterized protein PM1201.
Protein: ACAP1_ARATH
Sequence: MEEDLIKRLEAAVTRLEGISSNGGGVVSLSRGGDFSSAAGIDIASSDPSILAYEDLISQCVGRALTAAEKIGGPVLDVTKIVAEAFASQKELLVRIKQTQKPDLAGLAGFLKPLNDVTMKANAMTEGKRSDFFNHLKAACDSLSALAWIAFTGKDCGMSMPIAHVEESWQMAEFYNNKVLVEYRNKDADHVEWAKALKELYLPGLREYVKSHYPLGPVWNASGKPASAPAKGPPGAPAPPPAPLFSAESSKPSSSSNQKQGMSAVFQQLSSGAVTSGLRKVTDDMKTKNRADRSGAVSAVEKETRTSKPAFSKTGPPKMELQMGRKWAVENQIGKKDLVISECDSKQSVYIYGCKDSVLQIQGKVNNITIDKCTKVGVVFTDVVAAFEIVNCNNVEVQCQGSAPTVSVDNTTGCQLYLNKDSLETAITTAKSSEINVMVPGATPDGDWVEHALPQQYNHVFTEGKFETTPVSHSGA
What is the function of this protein?
Actin monomer binding protein that accelerates the exchange of ADP for ATP.  Regulates the pool of unpolymerized ATP-actin.  Key intermediate between actin-depolymerizing factor (ADF)-mediated disassembly and the profilin-based nucleation and elongation machinery.
What are the official names of this protein?
Cyclase-associated protein 1, AtCAP1, Adenylyl cyclase-associated protein.
What is the protein family that this protein belongs to?
Belongs to the CAP family.
Protein: EPHA5_CHICK
Sequence: MGLRGGGGRAGGPAPGWTCLLLCAALRSLLASPGSEVNLLDSRTVMGDLGWIAYPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGRPASSFELKFTLRDCNSLPGGLGTCKETFNMYYFESDDEDGRNIRENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLTKKGFYLAFQDVGACIALVSVRVYYKKCPSVIRNLARFPDTITGADSSQLLEVSGVCVNHSVTDEAPKMHCSAEGEWLVPIGKCLCKAGYEEKNNTCQVCRPGFFKASPHSPSCSKCPPHSYTLDEASTSCLCEEHYFRRESDPPTMACTRPPSAPRSAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHSGLCEACGSHVRYLPQQTGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDQNPGARQFVSVNVTTNQAAPSPVSSVKKGKITKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETAITADGLKPGSAYVFQIRARTAAGYGGFSRRFEFETSPVLAASSDQSQIPIIVVSVTVGVILLAVVIGFLLSGSCCDHGCGWASSLRAVAYPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLQGKREFPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVMSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKFDEIVSMLDKLIRNPSSLKTLVNASSRVSNLLVEHSPVGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDSVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVNGMVPL
What is the function of this protein?
Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.  The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.  Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5.  Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, entorhino-hippocampal and hippocamposeptal pathways.  Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis (By similarity).
What are the official names of this protein?
Ephrin type-A receptor 5, EPH-like kinase 7, EK7, cEK7.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, axon. Cell projection, dendrite.
Protein: RL27_LACJO
Sequence: MMINNLEALKLFAHHKGGGSTANGRNSAGRRLGAKRADGQKINAGSIIFRQRGTKIHPGKNVGIGGDDTLFALTSGVVKFERLGRDRKQVSVYPVEEAK
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RNR_UREPA
Sequence: MSDFTKQTITEVISKEERPIPAAILAKKVLEKIPTLNKTDVYKLIDLLIQENTIKKLENNRLVIGYLDYEFDHEIKQGIITINSKGDGFIKEDNTEIEYYVNKKYLNGALKKDSVKFVKLKKEPKNNLQDAAVIEIVGHAKDHYVGQFITLPNGGYYIFVDDPLFYLNINLKDTTGLVNGHKILFKIISQTTKDAIAELVHIIGHKNDVGSDVLSIVYDNGIDPTFDPQVVDLASKLEFYVDEHQNKIRRSIIDREIISIDPVGSKDIDDAVYVKKLNDQRYFLGISIADVSFYVQPNTILDADAFKRGTSTYLVDRVIPMLPHNISNNICSLNEGEFRMCITCDMVIDKDGKICWKDVYPAIMKNYRQMSYDEVNDFYEGKSRFESATLTMKEMLLEAKELHHILRNKKIKDGYVDFDIKEPKIILDETGVPIDIKIYERKTAQMMVEDFMIAANEAVTMFAEEHMDKTLKEFNLEMPFIYRVHDKPSIINLQKFEIEAKKLSFNISHDFENIQPNTISNWLKMNDNHVNLPLISKLLLRSMAKASYEIINTGHFGLASDNYTHFTSPIRRYPDLIVHRLLWMFIFDSQSYTDKQRVELVNKLKLITEESNKNEIIAVKTERDVNAAKFAEYMNLHIGKEFIGVVTTVSSFGVFVELENTIEGLIRIKNLKDDFYDFIPENMTLVGQKRKKIITVGNKVRVRVIEANKLTRKIDFELVAQ
What is the function of this protein?
3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
What are the official names of this protein?
Ribonuclease R, RNase R, VacB protein homolog.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase R subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATE_ARCFU
Sequence: MMDYKKLGLKVGIEIHQQLDTKHKLFCLCPTLTREVEESNFEFFRYLRLKRSEIGEEDRAAKEEVERSRRFIYKYYDTTCLVEADEEPPREVNREALLIAIQVAKMLNMEVVDEVHVMRKIVIDGSNTTGFQRTALVAFGGFLEVDGKRVGVATLCLEEEACRKVEDGEGYAVYSLDRLGIPLVEIGTEPDIDSPEMAKKVAARLGMILRSTGKVKRGLGTIRQDVNISIRDGARVEIKGVQELDILDKIVEYEVLRQVNLLKIREELKQRGARVEEKVFDVTDVFSNTKSKIIRNKTVKAILLRGFGGIVGREIQPGRRLGTEFADIAKTYGLGGVFHTDELPAYGISEEEVSRLRDAVGAEDGDAVVMAAGDAVRVERALRRIIERAKHCLVGVPEETRKANEDGTTSYLRPLPGAARMYPETDVPPVVVTEEMLNVEIPELIEERARRYEKLLPKDLAWEIADSPYYRVFEEYSEKLQPTVVARVLYLAPAALRREGVEIERLEERHYRLVLDMVLRGDIAKEGAEEALKLLCQNPEMSAGQLKEKIGAAEDIDGFIAKLIEEKADLIAERGEGAFKPLMGLVMKEFRGKVDGKVVAEKLKKALKSALSQ
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).  The GatDE system is specific for glutamate and does not act on aspartate.
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit E, Glu-ADT subunit E.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatE subfamily.
Protein: MDFI2_HUMAN
Sequence: MSETELEKIKVRTAEHLENDKNNISWLKEDTQLTNAKHADEKPINAIVINSVSDFNITDGPAKENPNEKKLSESSTSLSSLEECQTTFSYLQTDTSVHHRDTDEECASLILACLFCQFWDCLLMLPGTCETVCTKMCCPSRRYHHTSDENHSRNDCSCNCDMDCSLFESCHETSECLELAMEISEICYR
What are the official names of this protein?
MyoD family inhibitor domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the MDFI family.
Protein: ALF_YEAST
Sequence: MGVEQILKRKTGVIVGEDVHNLFTYAKEHKFAIPAINVTSSSTAVAALEAARDSKSPIILQTSNGGAAYFAGKGISNEGQNASIKGAIAAAHYIRSIAPAYGIPVVLHSDHCAKKLLPWFDGMLEADEAYFKEHGEPLFSSHMLDLSEETDEENISTCVKYFKRMAAMDQWLEMEIGITGGEEDGVNNENADKEDLYTKPEQVYNVYKALHPISPNFSIAAAFGNCHGLYAGDIALRPEILAEHQKYTREQVGCKEEKPLFLVFHGGSGSTVQEFHTGIDNGVVKVNLDTDCQYAYLTGIRDYVLNKKDYIMSPVGNPEGPEKPNKKFFDPRVWVREGEKTMGAKITKSLETFRTTNTL
What is the function of this protein?
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
What are the official names of this protein?
Fructose-bisphosphate aldolase, FBP aldolase, FBPA, Fructose-1,6-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family.
Protein: GATB_ASPFU
Sequence: MLQQWLRQSPRAARVLRGSCCRGPQSGSLRHSPLPTAPHRCIRSLQTSATESKERIPLRKQLKQDAKALKAQKRQKRASEEASRTKWELTVGIEIHAQLNTETKLFSRASTSNTDTPNSNVALFDLAFPGSQPEFQATALLPALRAAIALNCDIQPVSRFDRKHYFYQDQPAGYQITQYYEPFAKNGYVDLFPHDGIAPEDGDHVRIGIKQIQLEQDTAKSQEYPPSTQLLDFNRVSHPLIEIITMPQIHNPATAAACVRKIQAVLQSCSAVTTGMELGGLRADVNVSIRRRDEAPGTHQYGGIGGLGQRTEIKNLSSFKAVEDAVIAEKNRQIAVLESGGVIEGETRGWTIGSTETRKLRGKEGEVDYRYMPDPDLPPLIIGHDLISNLRDSLPTPPDQLIEMLAGTEYGLSIEDAKPLIELDDGARLEYYQDVVDILRDLQQDKDAKSRGGLARMAGNWVLHELGGLCTKADLAWDAQRVPAETLAQIIDQLQRKRITGATAKQVLAMVFDGDRRPVPQLLEEENLLLRPLSRDEYLALAEAAIGQNPQMVEQIRAKNQLGKLGWFVGQMMRMGEKGRVEAQKADEILRELILGKSDQP
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial, Glu-AdT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SEC11_PICGU
Sequence: MNLRQQLTQFLTMAFVFSSSFMAWKTLSVVTNSHSPVVVVLSGSMEPAFQRGDILFLWNRQRQNKVGDVVVYEIKGKDIPIVHRVLREHHNSEKQYLLTKGDNNLVDDLGLYAKKQGYLNQATDLVGTVKAYLPKVGYVTILISENMYARYALLGIMCISSLLTGE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: MOAC_XANCP
Sequence: MPAKTTSARLTHLDDAGLPTMVDVSDKQVTARSATAESRVHFPAAVAAQLRANGLRSAKGGIVETAVIAGTMAVKRTHELIPFCHPLPIDGCRFEIDWAGAQVLQIVCTVRCVHRTGVEMEALTGASVAALTVYDMCKALSHTMRIGPTKLLSKRGGKRDIGAAR
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: DFRA_CALCH
Sequence: MKEDSPPTVCVTGAAGFIGSWLVMRLLERGYIVRATVRNPGDMKKVKHLLELPKAETNLTLWKADLTQEGSFDEAIEGCHGVFHVATPMDFESKDPENEIIKPTIEGILSIIRSCAKAKTVKKLVYTSSAGTVNVQETQLPVYDESHWSDLDFIYSKKMTAWMYFVSKTLAEKAAMEAAKENNIDFVSIIPPLVVGPFINPTFPPSLITALSLINGAESHYSIIKQGQYVHLDDLCECHIFLYENPEAKGRYICSKQDATIHQLARMIKQKWPEYHVPTQFAGIDEELPTVSFSSKKLIDMGFKFKYDLEDMFKGAIDSCKEKGFLPYSTNEVKKGLFESSINGNVHGQKGNQKIGDEGVKLVN
What is the function of this protein?
Bifunctional enzyme involved in flavonoid metabolism.
What are the official names of this protein?
Dihydroflavonol 4-reductase, DFR, Dihydrokaempferol 4-reductase, Flavanone 4-reductase, FNR.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.
Protein: AGO1B_ORYSJ
Sequence: MALQLENGRPHHHQVPIMVKKKRTGSGSTGESSGEAPGAPGHGSSQRAERGPQQHGGGRGWVPQHGGRGGGQYQGRGGHYQGRGGQGSHHPGGGPPEYQGRGGPGSHHPGGGPPDYQGRGGSGSHHPGGGPPEYQPRDYQGRGGPRPRGGMPQPYYGGPRGSGGRSVPSGSSRTVPELHQAPHVQYQAPMVSPTPSGAGSSSQPAAEVSSGQVQQQFQQLATRDQSSTSQAIQIAPPSSKSVRFPLRPGKGTYGDRCIVKANHFFAELPDKDLHQYDVSITPEVTSRGVNRAVMFELVTLYRYSHLGGRLPAYDGRKSLYTAGPLPFASRTFEITLQDEEDSLGGGQGTQRRERLFRVVIKFAARADLHHLAMFLAGRQADAPQEALQVLDIVLRELPTTRYSPVGRSFYSPNLGRRQQLGEGLESWRGFYQSIRPTQMGLSLNIDMSSTAFIEPLPVIDFVAQLLNRDISVRPLSDSDRVKIKKALRGVKVEVTHRGNMRRKYRISGLTSQATRELSFPVDDRGTVKTVVQYFLETYGFSIQHTTLPCLQVGNQQRPNYLPMEVCKIVEGQRYSKRLNEKQITALLKVTCQRPQERELDILRTVSHNAYHEDQYAQEFGIKIDERLASVEARVLPPPRLKYHDSGREKDVLPRVGQWNMMNKKMVNGGRVNNWACINFSRNVQDSAARGFCHELAIMCQISGMDFALEPVLPPLTARPEHVERALKARYQDAMNMLRPQGRELDLLIVILPDNNGSLYGDLKRICETDLGLVSQCCLTKHVFKMSKQYLANVALKINVKVGGRNTVLVDALTRRIPLVSDRPTIIFGADVTHPHPGEDSSPSIAAVVASQDWPEVTKYAGLVSAQAHRQELIQDLFKVWQDPHRGTVTGGMIKELLISFKRATGQKPQRIIFYRDGVSEGQFYQVLLYELDAIRKACASLEPNYQPPVTFVVVQKRHHTRLFANNHNDQRTVDRSGNILPGTVVDSKICHPTEFDFYLCSHAGIQGTSRPAHYHVLWDENKFTADELQTLTNNLCYTYARCTRSVSIVPPAYYAHLAAFRARFYMEPETSDSGSMASGAATSRGLPPGVRSARVAGNVAVRPLPALKENVKRVMFYC
What is the function of this protein?
Probably involved in the RNA silencing pathway.  May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity).
What are the official names of this protein?
Protein argonaute 1B, OsAGO1b.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Ago subfamily.
Protein: RL14_STAEQ
Sequence: MIQQETRLKVADNSGAREVLTIKVLGGSGRKTANIGDIIVCTVKNATPGGVVKKGDVVKAVVVRTKSGVRREDGSYIKFDENACVIIRDDKGPRGTRIFGPVARELREGNFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.