PharMolix/UniProtQA huggingface dataset:
Protein: UBIA_PSEFS
Sequence: MYQRLLKSLNHLNPRAWDFVQLTRMDKPIGIYLLLWPTLWALWIAGKGSPSLINIVIFVLGVVLTRAGGCVINDWADRKVDGHVKRTEQRPLVSGKISSKEALVFFAVLMGISFLLVLLTNATTILLSLGGLALAASYPFMKRYTYYPQVVLGAAFSWGMPMAFTAETGDLPATAWLLYIANLLWTVGYDTYYAMTDRDDDLKIGVKSTAILFGDADRVIILTLQGLSLVCLLLAGARFELGGWFHLGLLAAAGCFAWEFWYTRDKDRMKCFKAFLHNHWAGLAIFVGIVADYAFR
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DIAC_HUMAN
Sequence: MSRPQLRRWRLVSSPPSGVPGLALLALLALLALRLAAGTDCPCPEPELCRPIRHHPDFEVFVFDVGQKTWKSYDWSQITTVATFGKYDSELMCYAHSKGARVVLKGDVSLKDIIDPAFRASWIAQKLNLAKTQYMDGINIDIEQEVNCLSPEYDALTALVKETTDSFHREIEGSQVTFDVAWSPKNIDRRCYNYTGIADACDFLFVMSYDEQSQIWSECIAAANAPYNQTLTGYNDYIKMSINPKKLVMGVPWYGYDYTCLNLSEDHVCTIAKVPFRGAPCSDAAGRQVPYKTIMKQINSSISGNLWDKDQRAPYYNYKDPAGHFHQVWYDNPQSISLKATYIQNYRLRGIGMWNANCLDYSGDAVAKQQTEEMWEVLKPKLLQR
What is the function of this protein?
Involved in the degradation of asparagine-linked glycoproteins.  Hydrolyze of N-acetyl-beta-D-glucosamine (1-4)N-acetylglucosamine chitobiose core from the reducing end of the bond, it requires prior cleavage by glycosylasparaginase.
What are the official names of this protein?
Di-N-acetylchitobiase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: SIPB_SALTI
Sequence: MVNDASSISRSGYTQNPRLAEAAFEGVRKNTDFLKAADKAFKDVVATKAGDLKAGTKSGESAINTVGLKPPTDAAREKLSSEGQLTLLLGKLMTLLGDVSLSQLESRLAVWQAMIESQKEMGIQVSKEFQTALGEAQEATDLYEASIKKTDTAKSVYDAAAKKLTQAQNKLQSLDPADPGYAQAEAAVEQAGKEATEAKEALDKATDATVKAGTDAKAKAEKADNILTKFQGTANAASQNQVSQGEQDNLSNVARLTMLMAMFIEIVGKNTEESLQNDLALFNALQEGRQAEMEKKSAEFQEETRKAEETNRIMGCIGKVLGALLTIVSVVAAVFTGGASLALAAVGLAVMVADEIVKAATGVSFIQQALNPIMEHVLKPLMELIGKAITKALEGLGVDKKTAEMAGSIVGAIVAAIAMVAVIVVVAVVGKGAAAKLGNALSKMMGETIKKLVPNVLKQLAQNGSKLFTQGMQRITSGLGNVGSKMGLQTNALSKELVGNTLNKVALGMEVTNTAAQSAGGVAEGVFIKNASEALADFMLARFAMDQIQQWLKQSVEIFGENQKVTAELQKAMSSAVQQNADASRFILRQSRA
What is the function of this protein?
Required for entry into the host cell through presentation or delivery of SipC at the host cell plasma membrane.  Along with SipC, is necessary for the transfer of other effector proteins into the host cell.  Induces macrophage apoptosis either by binding and activating the proapoptotic enzyme caspase-1 (caspase-1 dependent), resulting in the release of interleukin-1 beta active form, or by disrupting mitochondria and inducing autophagy (caspase-1 independent).  The former is dependent of its membrane-fusion activity.  The SipBC complex, in association with its chaperone SicA, is regulated by binding of InvE (By similarity).
What are the official names of this protein?
Cell invasion protein SipB, Effector protein SipB.
What is the protein family that this protein belongs to?
Belongs to the invasin protein B family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane; Multi-pass membrane protein. Note=Secreted via the type III secretion system 1 (SPI-1 TTSS) and inserted into the host cell plasma membrane.
Protein: BRD4A_XENLA
Sequence: MSSETGLGTRLRATSGMGDGIEGAQMLGQHQPALPQPQATVMNNPDPPEITRPNQPKRQTNQLQYLLKAVLKTLWKHQFAWPFQLPVDVVKLNLPDYHKIIKTPMDMGTIKKRLENHYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKISEMPQEETELTVVQSKGRGRGRKEQDASITPMRTRVLSGSLEDKSTVKPPVTPVSKPSTPTPPTVTRAPTPPQTRPQQGRPPAIAQAPIRFSPTISQDVVVPTTVAPTLVPPPLSNHPAVIHTAAQPAKTKKGVKRKADTTTPTTHDPLHESSPLPSDPKPPRAVPRKENGRQIRPTKKTEVPDSQLPAPPVLHPQPAPNAERDTKTSEQLRYCASIIREMFSKKHQAYAWPFYKPVDVEALGLHDYCEIIKHPMDLGTIKVKMENRDYKEAQEFASDVRLMFSNCYKYNPPDHEVVIMARKLQDVFEMRFAKMPDEPEEAPAPVPSLAPGPPAPSIKGPPPTSSDSSSDSTSDSESSSDSEEERAQRLAELQEQLKAVHEQLAALSQPQPNKPKKKEREKRKEKHKRKEEVEEPRKGRIREPPAKKPKKSVQGSGGTPSIKKEAPPPAPRPARPAPPSAPCESSEEETQRCRPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKSQDKIEAPTSGTVKVKGYSSSESESSSESSTSDSEESDSETAPNQKKKGHSGRESRKHHHPMQQPLAAQLPVMKPPSPTIAPSYPLPSSLDSSHISLHHPLHPANVFDAVMQLPPDLPPHLTGQTEHCSPPHLNQHALTSPPALHNAMPQQPSRPSNRAAALPTKPAMPPSASPPPPAPQPPQQPHVHHHHHHHAQPPHVLLEDDEPPSPLTGLPPYLQPLQKSQQPPTQSPIHSLLTSVKVQSQTPMAAPPQSMRHLQPLVYPPPPSTATTAPPPASSHIHQLQSSPVVPQQLPAGQAPPPPQQQQQHPALQGTLVSSHQQHVQHQHAKQQQVIQHHHHHPSPRQQKQETYPGGHLRDAPSPLLLHSPPVPPYPGLTHPPSPQSVQPKKQEIRGASVLQPQPVVMKEDKRHSPSIRPEGFSPGMRPEPQKVPEVLKGPSHIQPRPDLKKMDGGRPIRLPDQSLPPQGMPEKEKQKQEPKTPVAPKKDIKIKNMGSWAGLMQKPPVTPTSAGKSTSDSFELFRRQAREKEERERALKLQAEQAERVRREQDRMSRTREDDEVQDQARKAHEEARRRQEQQQQQQHVQSNLPTAPSPAQSSQPMMDQREMARKREQERRRRQAMAPSIDMNFQSELMEIFEQNLFS
What is the function of this protein?
Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation.  Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for postmitotic G1 gene transcription by preserving acetylated chromatin status and maintaining high-order chromatin structure.  During interphase, plays a key role in regulating the transcription of signal-inducible genes by associating with the P-TEFb complex and recruiting it to promoters (By similarity).
What are the official names of this protein?
Bromodomain-containing protein 4A.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associates with acetylated chromatin.
Protein: RISB_CROS8
Sequence: MNIIEATVAAPDARVAIAIARFNNFINDSLLEGAIDALKRIGQVKDENITVVWVPGAYELPLAAQALAKTAKYDAVIALGTVIRGGTAHFEYVAGGASNGLAHVAQHSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIQA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: ACP_STAEQ
Sequence: MENFDKVKDIIVDRLGVDADKVTEDASFKDDLGADSLDIAELVMELEDEFGTEIPDEEAEKINTVGDAVKYINSLEK
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4E_THEVO
Sequence: MINKTKRLMVPRTVKIPRKTYFWGPTPLPGRHKADHSVTLLTIIRDYLRLSDKEREATRILANGLVKVDGKVVKERKFGVGFMDVIEISGESYRVVYNNQGALVLVSESKDRANMKPLQVKNKVIAPGNKIQLGFHDGRVMVTEDRSISVGDVVIASLPDMKITEIIKMQPGNKAFITGGSHVGETGTISKIEIKESSSANLVHFDEGFTTVKDHVFVIGSPRFTFTMPSGEVYP
What are the official names of this protein?
30S ribosomal protein S4e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
Protein: ATPD_CHRSD
Sequence: MAETSTVARPYAKAAFEYARDHKALEAWSGQLASAKQVAADADFDAKVVSNPKLSHDQKTALLLEVCGELDESLCNFIRTVGSRGRLAALPAIAEQFEVLRAEEEKRVDVTIVSAFDLDAAQQDKLATALKKRLNREISITTRVDRALMGGVILRAGDTVIDGSVRGRLTRLRDALSA
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: C71DA_SOYBN
Sequence: MVMELHNHTPFSIYFITSILFIFFVFFKLVQRSDSKTSSTCKLPPGPRTLPLIGNIHQIVGSLPVHYYLKNLADKYGPLMHLKLGEVSNIIVTSPEMAQEIMKTHDLNFSDRPDFVLSRIVSYNGSGIVFSQHGDYWRQLRKICTVELLTAKRVQSFRSIREEEVAELVKKIAATASEEGGSIFNLTQSIYSMTFGIAARAAFGKKSRYQQVFISNMHKQLMLLGGFSVADLYPSSRVFQMMGATGKLEKVHRVTDRVLQDIIDEHKNRNRSSEEREAVEDLVDVLLKFQKESEFRLTDDNIKAVIQDIFIGGGETSSSVVEWGMSELIRNPRVMEEAQAEVRRVYDSKGYVDETELHQLIYLKSIIKETMRLHPPVPLLVPRVSRERCQINGYEIPSKTRIIINAWAIGRNPKYWGETESFKPERFLNSSIDFRGTDFEFIPFGAGRRICPGITFAIPNIELPLAQLLYHFDWKLPNKMKNEELDMTESNGITLRRQNDLCLIPITRLP
What are the official names of this protein?
Cytochrome P450 71D10.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: CYOA_HAEIN
Sequence: MLDVVDLSRLQFALTALYHFIFVPLTLGLSFILVIMETIYVATGKEVYKDMTKFWGKLFGINFALGVTTGIIMEFQFGTNWSYYSHYVGDIFGAPLAIEALLAFFLESTFVGLFFFGWDRLSKGKHLLATYCVAFGSNLSAMWILVANGWMQAPTGSEFNFETVRMEMTNFLDLWLNPVAQSKFLHTLSAGYVTGAFFVLAISSYFLLKGRDFEFAKRSFSVAATFGFIASISVLILGDESGYDIGKAQPVKLAAMEAEFETHPAPAPFLPVAIPNTAEMKNDFAIEIPYLGGVIATRSIDKEIIGLKDLQALNETRVRSGIRAYELFTQLRAEKKANGQVNEETKAQFNEVKKDLGFGLLLKRYTNNVVDATEEQIKQAARDTIPNVGPNFWAFRAMIAAGGLIALLTFGAFVQNLRNKVTQIPLLLKVLLWGLPLPWIAIECGWFLAEYGRQPWATYEILPVGVSASNLSTGDLWFSIGLICALYLAFIIVEMYLMFKYARLGPSALKTGKYYFEQSAK
What is the function of this protein?
Probable cytochrome oxidase subunit.
What are the official names of this protein?
Probable cytochrome oxidase subunit 1, Cytochrome oxidase subunit I.
What is the protein family that this protein belongs to?
Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LPOA_ECOLI
Sequence: MVPSTFSRLKAARCLPVVLAALIFAGCGTHTPDQSTAYMQGTAQADSAFYLQQMQQSSDDTRINWQLLAIRALVKEGKTGQAVELFNQLPQELNDAQRREKTLLAVEIKLAQKDFAGAQNLLAKITPADLEQNQQARYWQAKIDASQGRPSIDLLRALIAQEPLLGAKEKQQNIDATWQALSSMTQEQANTLVINADENILQGWLDLQRVWFDNRNDPDMMKAGIADWQKRYPNNPGAKMLPTQLVNVKAFKPASTNKIALLLPLNGQAAVFGRTIQQGFEAAKNIGTQPVAAQVAAAPAADVAEQPQPQTVDGVASPAQASVSDLTGEQPAAQPVPVSAPATSTAAVSAPANPSAELKIYDTSSQPLSQILSQVQQDGASIVVGPLLKNNVEELLKSNTPLNVLALNQPENIENRVNICYFALSPEDEARDAARHIRDQGKQAPLVLIPRSSLGDRVANAFAQEWQKLGGGTVLQQKFGSTSELRAGVNGGSGIALTGSPITLRATTDSGMTTNNPTLQTTPTDDQFTNNGGRVDAVYIVATPGEIAFIKPMIAMRNGSQSGATLYASSRSAQGTAGPDFRLEMEGLQYSEIPMLAGGNLPLMQQALSAVNNDYSLARMYAMGVDAWSLANHFSQMRQVQGFEINGNTGSLTANPDCVINRNLSWLQYQQGQVVPVS
What is the function of this protein?
Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).  Stimulates transpeptidase activity of PBP1a in vitro.
What are the official names of this protein?
Penicillin-binding protein activator LpoA, PBP activator LpoA, Lipoprotein activator of PBP from the outer membrane A.
What is the protein family that this protein belongs to?
Belongs to the LpoA family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side. Note=Localizes at the sidewall of elongating cells.
Protein: ENO_TUBBO
Sequence: MITKIHARSVYDSRGNPTVEVDLTTTDTGLHRAIVPSGASTGQHEAIELRDKDKTKWAGKGVLKAVENVNTIIAPALIKEKFDVKDQATIDKFLIDLDGTPNKAKLGANAILGVSLAVAKAGAAAKKVPLYAHVADLAGTKKPFVLPVPFMNVINGGSHAGGRLAFQEFMIVPSEAPSFTEAMRQGAEVYQILKTLTKKKYGQSAGNVGDEGGWPDIQTVEEALDLITDAIDKAGYTGQIKIAMDVASSEFYKEDAKKYDLDFKNPDSDSSKWLTYQELADLYKSLAQRYPIVSIEDPFAEDDWEAWAHFYKTSDFQIVGDDLTVTNPIRIKRAIDEKSCNALLLKVNQIATLTESIQAAKDSYSAGWGVMVSHRSGETEDVTIADIVVGLRAGQIKTGAPARSERLAKLNQILRIEEELGEQAIYAGTSSEPPHLYIFI
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROB_HELHP
Sequence: MQKPRIVLKIGSSNLCNGKIIDKTQIKALAQIISELKMRFDVILVSSGAVASGHTTLHIDRNTLQNKQALASIGQPLLMESYREALKDYAIPTAQLLLVWRDFDSRKNTTFAKDTIDTLLAHNALPIINENDTIATDEMVFGDNDRLGAYVTYYFGAKLLIILSDIDGYFDKNPHQYDDAQILPIVHSIPSQALEQTHSPHGDFATGGIVTKLIAADFLLQRKCMMFLSHGRKLDVLRDFLLHNKQSSGTLFCPADSQGIKTLI
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN112_MOUSE
Sequence: MTKLQEMVTFRDVAVVFSEEELGLLDAAQWKLYREVMLENFRMLLSVAHQPFKPGLIAQLENGEQLWMVEAEAHAGGLSGRRNGHAVENAEDVEVNSLCPEDLSFCQTWPWGACTLPSGQEFIKRCQGSNGESQSQEASPRLVWAGMPMQISEDGNYGLPPAHEDSASMKNQEFPPPRSQQSQGEPYLGRPCVTCQWKGQQTSIRNHFCRYGSVCWSPYHSDNEELYSKGKSYGFHDDRGKTVKVLLLNQDFIELGPEPCPRTKNREAWGHDNDHSSHTHQQCHSRGKPCTRSLSGEGCGDRSALHGHPGLEAGDEGADGSPPLQSSPRVCMEQVPRECSGNVHYGSPLNTCGCAHPGNTSQTCSIPKQAVGSPVHCNSTFRAHPREEPNNYEENRNVFNQSSCLQVSRKIGAEEKLCQGVECRKNFTHCSSLNIPHRVPVEETLCNPDCGNHFSLPPHFQDFPGVRAREQPHNRLCRTGFSQTLCLQGHQKLHIREKPSHREGGSGCNWSSTPKDPQKQKLHKCNACGKGFSHRSVLDIHHRIHTGEKPYKCEECGKGFSRSAYLQGHQRVHTGEKPYKCEECGKGFSRSSHLQGHQRVHTGEKPYKCEECGKGFSWSFNLQIHQRVHTGEKPYKCGECGKGFSKASTLLAHERVHTGEKPYQCHECGKNFSQKSYLQSHQSVHSGERPHICEVCGKGFSQRAYLQGHLRVHTRVKPYKCEVCGKGFSQGSRLEAHQRVHTGRKPFKCETCTKGFSESSRLQAHQRIHEEGRPYKCDQCGKGFSGYSSLQAHHRVHTGEKPYKCEVCGKGFSQRSNLQAHQRVHTGEKPYTCDACGKGFRWSSGLLIHQRAHSSDTFYRSGECGSSYPPENLCRNEGL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 112, Zfp-112.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS1_BUCAI
Sequence: MNESFAQLFEESLKEIKTRPGSIIRGTIVSIEKDMVLVDAGLKSESAIPVEQFQNSQGLLDIQVGDQIDVALDAIEDGFGETLLSREKAKRHEAWLILEKAHEKSETVIGIINGKVKGGFTVELNDIRAFLPGSLVDVRPVRDTIHLEGKELEFKVIKLDQKRNNVVVSRRAVIESENSAERDQLLENLQEGMHVKGIVKNLTDYGAFVDLGGVDGLLHITDMAWKRVKHPSEIVNVGDEINIKILKFDRERTRVSLGLKQLGEDPWIAISKRYPEETKLSGRVTNLTDYGCFVEIEEGVEGLVHVSEMDWTNKNIHPSKVVTVNDVVEVMVLDIDEERRRISLGLKQCKINPWKEFSETHKKGVHVLGKIKSITDFGIFIGLNGGIDGLVHLSDISWTIPGEEAVVKYKKNDEISAVVLQVDAERERISLGIKQLEEDPFNTYIANHKKGAIITGIIKSLDKKNIIVKLPENLEGVIKLTEITRVYSETMINKLKIEDKILVKLSSFDRKNRIIYLTIHMIDEDEKKDLTAPSNNKTNDDSFSNVMTEAFKAAKNTE
What is the function of this protein?
Binds mRNA; thus facilitating recognition of the initiation point.  It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity).
What are the official names of this protein?
30S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS1 family.
Protein: SSTT_YERP3
Sequence: MEKTQSVFIRFIVNGSLVKQILIGLVAGIVLALVSTPAAIAVGLLGSLFVGALKAVAPVLVLMLVIASIANHKKGQKTSIRPILFLYVLGAFSAALVAVVVSFIYPSTLILVAESADITPPSGIVEVLHGLLNSIIANPIHALLNANYIGILAWAVGLGIALRHAADTTKALINDMSDAVTLVVRVVIRFAPLGIFGLVASTIAATGFGALQLYVQLLVVLIGCMLLVALVVNPLIVYWKIRRNPYPLVFACLRESGVTAFFTRSSAANIPVNMEMCKKMNLNEDTYSISIPLGATINMAGAAITITVLTLAAVHTLGITVDLPTALLLSVVAAVCACGASGVAGGSLLLIPLACSMFGIPNDVAMQVVGVGFIIGVLQDSAETALNSSTDVLFTAAVCQAEDAKLANPDALAAGKSV
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TAM_RHIEC
Sequence: MAWSASQYAKFEDERTRPARDLLAQVPLQHLRRAIDLGCGPGNSTELIIERYGADGVSGLDSDANMLEAARKRLPGTAFVEADLGSWQPTEPADLLFANAVFQWLPDHLDIFERLMDGLSEGGVLAVQMPDNLGEPSHLAMEETAHGGPWKAAFEEKGVRRQPLAPPSSYYSRLIAKAARVDIWHTIYNHPMADAAAIVEWVKGTGLMPYLARAGEKHREAFLADYLERIEKTYPKMSDGRVLLRFPRIFIVAVKG
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REP_TMOV
Sequence: MPPPKKFRVQSKNYFLTYPQCSLSKEEALSQLQNLNTPVNKKFIKICRELHENGEPHLHVLVQFEGKYQCTNNRFFDLVSPTRSAHFHPNIQGAKSSSDVKSYIDKDGDTIEWGDFQIDGRSARGGQQSANDSYAKALNAGSVQSALAVLREEQPKDFVLQNHNIRSNLERIFAKAPEPWVPPFQVSSFTNVPDEMQEWADNYFGTGDAAPPDRPVSIIVEGDSRTGKTMWARALGPHNYLSGHLDFNGRVFSNDVQYNVIDDIAPHYLKLKHWKELLGAQKDWQSNCKYGKPVQIKGGIPAIVLCNPGEGASYKEFLDKAENTGLKNWTIKNAIFITLTAPLYQESTQASQETGNQKAQG
What is the function of this protein?
Essential for the replication of viral ssDNA.  The closed circular ssDNA genome is first converted to a superhelical dsDNA.  Rep binds a specific region at the genome origin of replication.  It introduces an endonucleolytic nick within the conserved sequence 5'-TAATATTAC-3' in the intergenic region of the genome present in all geminiviruses, thereby initiating the rolling circle replication (RCR).  Following cleavage, binds covalently to the 5'-phosphate of DNA as a tyrosyl ester.  The cleavage gives rise to a free 3'-OH that serves as a primer for the cellular DNA polymerase.  The polymerase synthesizes the (+) strand DNA by rolling circle mechanism.  After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication.  Displays origin-specific DNA cleavage, nucleotidyl transferase, ATPase and helicase activities (By similarity).
What are the official names of this protein?
Replication-associated protein, Rep, Protein AC1, Protein AL1.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae Rep protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RRAAH_BACAN
Sequence: MWKTTDLCDEFENELQICRQPFRSFGKKEQFHGKIATVKVKDDNVLVKEGLQTLPEGTVLVVDGGASTNCALLGDNLAAIAEERKLAGIIVNGYVRDSSELKNINIGILALGTMPNRSVKEGKGERNISLQFGQVEWKPDEYVYVDEDGVIISDKSLHR
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: RSGA_STRCO
Sequence: MTSTSSHSNHSALSSYGWDDSWADAFAPYAAEGLLPGRVVRVDRGQCDVVTADGVLRADTAFVTPHDPLRVVCTGDWVAVEPGGNPRYVRTYLPRRTAFVRSTSSKRSEGQILAANVDHAVVAVSLAVELDLARIERFLALAWESGAQPLVVLTKADLVPDPVTLAYLVQDVETAAPGVPVLPVSAEQGEGLDVLAAVVSGGTAVLLGQSGAGKSTLANALLGEAAMDVQAIRDVDGKGRHTTTTRNLLALPGGGVLIDTPGLRGVGLFDAGNGVDQVFAEIAELAEECRFHDCAHESEPGCAVLAAIDSGALPERRLESYRKLMRENQRIVAKTDARARAEIRKEYKRRGAIGKAAMEAKRGGLR
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNCB_SHIBS
Sequence: MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVHVAAEFRCRGDDLLGIYADAIREQIQAMQHLRLQDDEYQWLSALPFFKADYLNWLREFRFNPEQVTVSNDNGKLDIRLSGPWREVILWEVPLLAVISEMVHRYRSPQADVAQALDTLESKLVDFSALTAGLDMSRFHLMDFGTRRRFSREVQETIVKRLQQESWFVGTSNYDLARRLSLTPMGTQAHEWFQAHQQISPDLANSQRAALAAWLEEYPDQLGIALTDCITMDAFLRDFGVEFASRYQGLRHDSGDPVEWGEKAIAHYEKLGIDPQSKTLVFSDNLDLRKAVELYRHFSSRVQLSFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPHIKKAS
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: BEXD_HAEIF
Sequence: MRNYPLKAVCAVLMLGLSACSSLPTSGPTDSAVLEINQGADASELAAKVNVIELNESLVQQIYAAQQSQRFSGFADVRGNGGYAGAVNVGDVLEISIWEAPPAVLFGTTFSSEGQGSGHVTQLPSQIVNKNGTVTVPFVGNISVAGKTPEAIQAQIVASLSRKANQPQAVVKIANNNSSDVTVIRQGSAVRMPLTANDERVLDAVAAIGGSTGNIEDVTVQLTRGNQVKTLAFETLIADPKQNIVLRAGDVVSLLNTPYKFTGLGAVGNNQQLRFSSSGITLAEAIGKMGGLIDTRSDPRGVFVFRYMPFAQLDSKAQQEWAAKGYGNGMEVPTVYHANLLQPETMFLLQRFPIQDKDIVYVSNAPLSEFQKFLRIIFSITSPVTSTTNTIRSY
What is the function of this protein?
May form an ATP-driven capsule polysaccharide export apparatus, in association with the BexA, BexB and BexC proteins.  May function as a membrane anchor for capsular polysaccharides.  Possible porin properties.
What are the official names of this protein?
Capsule polysaccharide export protein BexD.
What is the protein family that this protein belongs to?
Belongs to the BexD/CtrA/VexA family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: LSPA_CHLPM
Sequence: MRWFFFLLLSVIGLDRFTKQLAIIFLRDTGESITIIPGLFSLTYAENRGIAFGMEFLPPGVLLILTTIIVSGVIIYALYQGNRQPLFLGSFGLIAGGGIGNLIDRFTTGRVVDFLYFDLYRGELFGQWIALWPIFNIADSAITIGACMLIIFYGRIFPDSTASGGNNVC
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SURE_DEHMC
Sequence: MRILVSNDDGIYSPGLWALVKRLKEVGEVIVVAPDREQSATGTQVTLRQPLRVQKTHPLIPGIEAYAVEGSPCDCVILGLAKLITEPVDLVVSGINHGLNLGDDVLISGTVGAALQGYLRNIPSIAISIPVTMEEPENLDSAACITAEVARRIQNGDITKNSFLNINIPDLPLSQIEELRVTPLAHKTHIETVEEGHDGRKRYFWLRRRQLSSADNKKTDIWAIENGYITISALHERLFQQPVFTLKDAETAGILAAARSCQDKI
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCL5_MACMU
Sequence: MKVSAARLAVILVATALCAPASASPHASDTTPCCFAYIARPLPRAHIKEYFYTSGKCSNPAVVFVTRKNRQVCANPEKKWVREYINSLEMS
What is the function of this protein?
Chemoattractant for blood monocytes, memory T-helper cells and eosinophils.  Causes the release of histamine from basophils and activates eosinophils.  May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5.  May also be an agonist of the G protein-coupled receptor GPR75.  Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases.  By activating GPR75 may also play a role in insulin secretion by islet cells.
What are the official names of this protein?
C-C motif chemokine 5, Small-inducible cytokine A5, T-cell-specific protein RANTES.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.