PharMolix/UniProtQA huggingface dataset:
Protein: SYGB_LACCB
Sequence: MTHQYLIEIGLEDMPAHVVTPSLQQFHDKTVAFLKENHLDHGAIDQYATPRRLALLIHDLADKQADVEEDVKGPAKKIAQDADGNWTKAAIGFSRGQGMTPDDIVFKTIKGVDYVYLHKAIKGKTAAAILPGMLDVIKSLTFPTRMKWGAYDFEYIRPIHWLVSLLDDAIVPMKLLDVDAGRTTQGHRFLGRPVTLGNAADYVAALKAQFVIVEPAARKQLISDQIHQIAADHQWQIDLDADLLEEVNNLVEWPTAFAGNFDEKYLKIPEAVLITSMKDNQRYFYARDASGKMVNAFIGVRNGNADHLANVIAGNEKVLTARLEDAAFFYAEDQKRSIADDVDRLKAVSFHDKISSMYDKMARTRVIADLLADRFGLSATDKADLDRAASIYKFDLVTSMVGEFPELQGIMGEHYAQLAGEKPAVAQAIAEHYEPISADGALPESLVGTVLAIADKFDSLMSFFAVDLIPSGSNDPYALRRQAYGIVRMIAKHDWPFAVAELQTTIADALKAAGKTNNLDFAAHQQDLNAFMIDRAKQVLQGQKIRHDIVDAVTVRADADLAGILDAAKILSAHADDTDFKPVMEALGRVLRITKKQQVKVDVDTAKFENPSEGQLYDATVATAKKFDDEPTEADYQALKALADPINAYFDATMVMADDQAIRQNRLAALLQLAALIKQFGDVSQVIVK
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_STRPS
Sequence: MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSEKSTLRALEEIESGNVTIHLDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGEKI
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: PGK_PELPB
Sequence: MQKKSLSDIAIQGKRVLMRVDFNVPLDSNKKITDDKRIIESLPSIKKVLENGGRLILMSHLGRPKGKVNADYSLAPVATRLAELLDCPVTMAKECIGTETMQQVLALQDGEVILLENLRFHPEEEANDPDFARELASLGEVYVNDAFGTAHRAHASTEGITHYVQTAVAGFLIERELLYLGKALQEPERPFVAILGGSKISGKIDVLENLFKKVDTVLIGGAMVFTFFKAQGYEIGNSLVEESKIELALKILDEAKNKGIKLLLPVDVIVAPEISATADCHSEMITAIPEEMIGVDIGPLTAEIYRNEILSARTVLWNGPMGVFEIDNFAAGTMAVAQAMAEATAEGATTIIGGGDSAAAVAKAGLANEMTHISTGGGASLEFLEGKELPGIAALND
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR2_CALFG
Sequence: MTRRYWHINLEEMMEAGVHFGHGTRKWNPRMAPYISAKRKGIHITNLTRTARFLSEACDLVFDAASIGKHFLIVGTKKKAADSVASAAIRARCHYVNKKWLGGMSTNWSTTETRLHKFRDLRAEQKAGKLNRLPKRDAAMLKRQLSHLQTYLGGIKYMTGLPDIVIIIDQQEEYTALRECLTLGIPTICLIDTNCDPDLADISIPANDDAIASIRLILNKLVSAICEGRSSYIRNC
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KHSE_CAUVC
Sequence: MAVYTDITDQELEAFLEGYDLGAPLAFKGIAEGVENSNFLLETEKGRYILTVYERRVKAEDLPYFLNMLTWLADRGYPSARPIPTRSGATLSSLRGKPAAIVEFLPGLSVRKPTAAHCREAGEGLAWLHLAGEGYPGRRANDLGQAAWSPLFSKHRKAAEDLKPGLSATIDNDLAQLSLMWPRNLPTGTIHADYFPDNVFFQSNGKFAAAIDFYFACDDAYAYDVAVTLNAWCFEADGSFNITAAKALLNGYERRRPLSPIEKEALPILARGAAMRFFLTRLADWGSTPAGALVRPKDPLEYERKLAVHREGLVLFA
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: Y4VI_SINFN
Sequence: MDDRQVQPGRVIVVTGAAGGIGRALVDIFAANGDVVVAVDLPDSGVIELGQNLGEPHLGLEVDVSREDDVVALRALLEKRFSRIEVLVNNAGIGPTMAATADTALEDFQRALAINLVGAYSVACETAKLMKPGAAIVNVASLAGLLGNPKRSAYAASKAGLISITKSLACRWASRGIRVTAVAPGHVRTPMVAELERAGKLDVSAIRRRVPLGRIARPDEIARAVRFLASAQASYITGSTLVVDGGWMSVNQPGGAHQAQDRTPGAEFMRPVEDTDARTVIVMGGATGVGAAIARRFAENGDTVVIADGDGEEAVKLAGLLGDKHLSRRVDRTVETEVVSLFEELRERFGHLDVFVNGMNEILVPNTEESPEVLKRILDVNLTGAFTCVREAAISMRSGSVILNLGASLSLSPLAPSHAYGAYNAGIDMLTRCTAAELGPLGIRTATVAPGYIRTCAANRLAAVAGMDSASLRQRIPLGRVGDAEEVAEAAYFLASFDASYINGSILHVDGGLISSREAGWGSEVDGAISAEMRPQRRPAARWRLLSP
What are the official names of this protein?
Uncharacterized short-chain type dehydrogenase/reductase y4vI.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: HAOX_ORYSI
Sequence: MEDNLPVNVREYQELAKKALPKMAYDYINGGAEDEHTLRENIAAYTRIILRPRVLVDVSKIDMSTTLLGYTMRSPIIVAPTGGHKLAHPEGEKATARAAASCNAIMVLSFSSSCKIEDVASSCNAIRFYQLYVYKNRNVSATLVRRAESCGFKALLLTVDTPMLGRREADIRNKMVFPRSGNLEGLMTIDDHDTTNGSQLERFARATLDPSLSWKDIEWLKSITSMPIFLKGIVTAEDARRAVEAGVAGVIVSNHGARQLDYAPATIAALEEVVRAVAGAVPVLVDGGIRRGTDVFKALALGARAVMXXXPVFFGLAARGEAGARHVIEMLNGELEVAMALCGCRSVGEITRSHVMTEGDRIRSLL
What is the function of this protein?
Oxidase that catalyzes the oxidation of a broad range of 2-hydroxyacids to the corresponding 2-oxoacids, with a reduction of O2 to H2O2.  May be involved in a general medium- and long-chain fatty acid catabolic pathway such as alpha-oxidation.
What are the official names of this protein?
Peroxisomal (S)-2-hydroxy-acid oxidase GLO4, Glycolate oxidase 4, GOX 4, OsGLO4, Short chain alpha-hydroxy acid oxidase GLO4.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: MATK_ABIHL
Sequence: MDEFHRYGKEDSSWQQCFLYPLFFQEDLYAIYHDHYLDGSSSSESMEHLSSNDQFSFLTVKRLIGQIRQQNNSIVFFLNCDPNPLVDRNKSFYYESVLEGLTLVLEVPFSIRSKYSVEGMNEWKSFRSIHSIFPFLEDKFPHSNYILDTRIPYSIHPEILVRTFRRWIRDAPSLHPLRSVLYKYRNSPDNFQKSIIIDPRVNTRFLLFLWNHYVYGCESILVPLLKRSFHPRSLSHGSFPDQTHFDRKIKHIIRNYRRNSLKSIWSLKDPRIHYVRYAERSIIAIKGTHLLVKKCRYHLPIFRQFYFHLWSEPYRVCSHQLSKNCSSSLGYFLRVRMKPLLVRTKMLDELFITDLITDEFDPIVPIVPIIGLLAREKLCDISGRPISKLYWTSLTDDDILDRFDRIWKNIFHYYSGSLDRDGLYRIKYILSLSCAKTLACKHKSTIRVVRKELGPELFKKDFSKEREFYFPAFSSKAAARSQRERIWHSDIPQINPLANSWQKIQDLKS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PURA_FUSNN
Sequence: MAGYVVVGTQWGDEGKGKIIDVLSEKADYVVRFQGGNNAGHTVVVDGEKFILQLLPSGVLQAGTCVIGPGVVIDPKVFLDEIDRIEKRGAKTDHVIISDRAHVIMPYHIEMDKIRESVEDRIKIGTTKKGIGPCYADKISRDGIRMSDLLDLKQFEEKLRYNLKEKNEIFTKIYGLEPLDFDTIFEEYKGYAEKIKHRIVDTIPMVNKALDENKLVLFEGAQAMMLDINYGTYPYVTSSSPTLGGVTTGAGISPRKIDKGIGVMKAYTTRVGEGPFVTEIKGEFGDKIRGIGGEYGAVTGRPRRCGWLDLVVGRYATEINGLTDIVMTKIDVLSGLGKLKICTAYEIDGVIHEYVPADTKSLDRAIPIYEELDGWDEDITQIKKYEDLPVNCRKYLERVQEILGCPISVVSVGPDRSQNIHIREI
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APF2_ARATH
Sequence: MVGRRKALLFSLCFFFLSLPSFSSLPSFQTLFPNSHSLPCASPVSFQPDSDSESLLESEFESGSDSESSSSITLNLDHIDALSSNKTPDELFSSRLQRDSRRVKSIATLAAQIPGRNVTHAPRPGGFSSSVVSGLSQGSGEYFTRLGVGTPARYVYMVLDTGSDIVWLQCAPCRRCYSQSDPIFDPRKSKTYATIPCSSPHCRRLDSAGCNTRRKTCLYQVSYGDGSFTVGDFSTETLTFRRNRVKGVALGCGHDNEGLFVGAAGLLGLGKGKLSFPGQTGHRFNQKFSYCLVDRSASSKPSSVVFGNAAVSRIARFTPLLSNPKLDTFYYVGLLGISVGGTRVPGVTASLFKLDQIGNGGVIIDSGTSVTRLIRPAYIAMRDAFRVGAKTLKRAPDFSLFDTCFDLSNMNEVKVPTVVLHFRGADVSLPATNYLIPVDTNGKFCFAFAGTMGGLSIIGNIQQQGFRVVYDLASSRVGFAPGGCA
What is the function of this protein?
Aspartyl protease.  Not able to cleave BAG6.
What are the official names of this protein?
Aspartyl protease family protein 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
Protein: CSN4_EMENI
Sequence: MPSQKIISALAEIESSASPQNKLQLYNDLLSETVSASPEPQLADDLIYYLDSVLSEDLSIVAARPILDSFIYTLRKLSSETQIKVAQHAVNLLQSRSASVEEQDAQIREILADAYEAEEEYIAAARALQGIHIDSSQRLVSDSAKVKLWIRIVRLYLEEDDTTSAEAFLNRIKNLPSKIEDHELKLHFRLSQARIQDARRRFLDASQEYFAVSLAAGVDESDRLQALAAAIRCAVLAPAGPQRSRTLATLYKDDRATSVEEFGILEKMFLDRLLTPEEVSAFAQRLAPHQLAQTADGTTVLDKAVVEHNLVAASKLYENIKTDALGAILGLQASGDLTAGEKAEAYAARMVEQGRLSGSIDQIDGIIYFESNTTATGRHIRQWDAGVQGLSEGVERVATNIAEGHLVR
What is the function of this protein?
Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes (By similarity).  The CSN complex seems to link protein degradation to sexual development.  Required for fruit body formation.
What are the official names of this protein?
COP9 signalosome complex subunit 4, Signalosome subunit 4.
What is the protein family that this protein belongs to?
Belongs to the CSN4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PURL_RHOPB
Sequence: MSSKPTPITPELVASHGLKPDEYQRILKLIGREPSLTELGIFSAMWNEHCSYKSSRLHLKGLPTKAPWVLQGPGENAGVIDIGDNEAIVFKMESHNHPSFIEPYQGAATGVGGILRDVFTMGARPIACLNALSFGAPEHPKTRHLVSGVVAGVGGYGNSFGVPTVGGQVRFDTRYDGNILVNAMAVGLADADKIFLAAASGVGMPIVYLGSKTGRDGIHGASMASAVFDDDSAEKRPTVQVGDPFAEKLLLEACLEIMAADCVIAIQDMGAAGLTSSAVEMGAKGNLGVDLDLDKVPTREPGMTAYEMMLSESQERMLMVLKPEKEREAEAIFKKWGLDFAIVGHTTPTLRFVVKHGGEVKADLPIKELGDEAPLYDRPHVETPKLPIIHARDIKPPIGVVEALEKLIGSPELCSRRWVWEQYDHVIGGNTVQRPGGDAAVVRIKDGPKGLALTVDVTPRYCEADPYEGGKQAVAEAYRNITAVGGKPLAITDNLNFGNPERPEIMGQLVGCLKGIAEACVALEAPIVSGNVSLYNETNGRGILPTPSIGGVGLLDDFTKSATLAFKAAGEAILLIGETRGWLGQSVYLRDICGREEGAPPPVNLDAEKRNGTVVRGMIHSGTATAVHDLSDGGLLIALAEMAIAGHIGAALDAGPEAIVPHAWWFGEDQARYLVTVPADELLGVLTKLKAVGVPCLQIGKTAGHTLSIAGERAIDIKALEHAHEAWLPNYMGGKA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M2_I70A0
Sequence: MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRFFEHGLKRGPSTEGVPESMREEYRKEQQSAVDADDSHFVSIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: ATPE_OCEIH
Sequence: MRTLEVSVVTPGGPVLEESFEMVVCKAETGEIGILPGHIPLVSPLQISAVRLKKGNDTKYLAISGGFMEVQPEKVTILAQSAETASDINVQRAKEAKDRAERRLQAKKDNIDKTRAELALKRAINRLDVGK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SYM_SHIF8
Sequence: MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGHEVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEENRQLSELIYSRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCEVCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANKMQEWFESGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDSVSFDEYWKKDSTAELYHFIGKDIVYFHSLFWPAMLEGSNFRKPTNLFVHGYVTVNGAKMSKSRGTFIKASTWLNHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFDGVLASELADPELYKTFTDAAEVIGEAWESREFGKAVREIMALADLANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTYLKPVLPKLTERAEAFLNTELTWDGIQQPLLGHKVNPFKALYNRIDMKQVEALVEASKEEVKATTAPVTGPLADDPIQETITFDDFAKVDLRVALIENAEFVEGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQALIGRHTIMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDAGAKPGHQVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPEV_SYNPY
Sequence: MSDSNQIKNSSQTQQVNTLSEEEALVLSAHLKEQRSSGIPLDSDQKSIDKMIAGLGDPRGLLRLRFADSLGSVGQAAVPALCNAMLSSDQVTVRRAAAKTLTLIEDPNSLPDLVSAFLNDQDSVVQGSAMGAMAAIGEEAVTPILNLLSHPETTEMQIGLANWALAFIGDRGSKTLRNALSSGNSTIRKAAIAALTSRIDTLNADENKDLLSNASNDDDSEIRAEVATLLGAMEDTDWAKLLLISNLDDPDSWVRKNSVLSLMKLNAKEALPKLEELELQEKDRIVVNVLKLAIQKLRQTD
What is the function of this protein?
An enzyme involved in the biosynthesis of bilin.
What are the official names of this protein?
Bilin biosynthesis protein MpeV.
What is the protein family that this protein belongs to?
Belongs to the CpcE/RpcE/PecE family.
Protein: CYC13_CATRO
Sequence: MANFISFFILFSALFFLFKRLFFPNRKQKLPPGPPSLPIVGHLHHIKTSLYQALARLSNEYGPVIFLRFGCRSFVAVSSPSAIEECFTKNDIIFANRPKSMATDRLTFNYIGFAWAPYGQFWRIVRRFTVVEFFSTNCLGKSRPIREEEIQSILRSIFKITKMKSEKIDLKHWVSVFTFNVLMRTMADKWAVDEEDSGVEKGKEIMKELREIFFTNVAMNVCDFFPIFRWFGYKGIEQRMINLHNRRNEFLQGLVDKVRINKKSGFVRNKESHRSLIEAFLSHQDQDPEFFTDDLIKSVLLIMFVAGTETSAVIIEWAMSLLLSNPDVLNKLRIEIDKQIGNKRLINESDIPKLPYLRCIINETMRLFPPVPLLLPHCSSEDCKIAGYDIPKGTVLFVNAWATHRDPKLWDEPEKFIPERFENMEVEKEGYKFIPFGIGRRACPGTSMGIRTVSLALGAFIQCFDWKKVEEYELNTSYDYRITLQKANQLEASCSPRQDFFPILSQL
What are the official names of this protein?
Cytochrome P450 81C13, CrCYP81C13.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: PIP14_ARATH
Sequence: MEGKEEDVRVGANKFPERQPIGTSAQSTDKDYKEPPPAPLFEPGELSSWSFYRAGIAEFIATFLFLYITVLTVMGVKRAPNMCASVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSLTRAVFYMIMQCLGAICGAGVVKGFQPTPYQTLGGGANTVAHGYTKGSGLGAEIIGTFVLVYTVFSATDAKRSARDSHVPILAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNKDHSWDDHWIFWVGPFIGAALAALYHQIVIRAIPFKSKS
What is the function of this protein?
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
What are the official names of this protein?
Probable aquaporin PIP1-4, Plasma membrane intrinsic protein 1-4, AtPIP1;4, Transmembrane protein C, TMP-C.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. PIP (TC 1.A.8.11) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UPPP_LACDB
Sequence: MLDIFKAIILGIIEGVTEFLPISSTGHLYLADYIIKLDQPTSFINMFMVVIQLGAILSVIVIYFNKLNPFAPSKSKREKGQTWQIWFKVIAAVLPSIIIGLPLNDWLEENMTSWQVISATLIIYGILFIVLENYYAKRQPSLTDLNKMSNKTALLIGCFQVLSMIPGTSRSGATILGAMLIGSSRYVATEFSFFLAIPTMFGASLLKLVKFFKAGHVFVGNQLAILLVGMVVSFIVAYLSIKFLLKYVQTHDFKPFGWYRIVLGIIVTICGLVFA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CHI5_PHAVU
Sequence: MKKNRMMIMICSVGVVWMLLVGGSYGEQCGRQAGGALCPGGNCCSQFGWCGSTTDYCGKDCQSQCGGPSPAPTDLSALISRSTFDQVLKHRNDGACPAKGFYTYDAFIAAAKAYPSFGNTGDTATRKREIAAFLGQTSHETTGGWATAPDGPYAWGYCFVRERNPSAYCSATPQFPCAPGQQYYGRGPIQISWNYNYGQCGRAIGVDLLNKPDLVATDSVISFKSALWFWMTAQSPKPSSHDVITSRWTPSSADVAARRLPGYGTVTNIINGGLECGRGQDSRVQDRIGFFKRYCDLLGVGYGNNLDCYSQTPFGNSLFLSDLVTSQ
What is the function of this protein?
Defense against chitin-containing fungal pathogens.
What are the official names of this protein?
Endochitinase CH5B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family. Chitinase class I subfamily.
What are the subcellular locations of this protein?
Vacuole. Note=Vacuolar and protoplast.
Protein: HTPX_YERPN
Sequence: MMRIALFLLTNLAVMLVFGLVLSLTGIQSSSVQGLMIMAGLFGFGGAFVSLLMSKWMALRSVGGEVIERPRNETEYWLLETVRRQSQQVGIAMPQVAIYQAPDINAFATGARRDASLVAVSTGLLQNMSRDEAEAVIAHEISHVANGDMVTMTLIQGVVNTFVIFISRLIAQIAAGFLSGDRDGESNSPGNPMVYFAVSMVLELVFGILASIITMWFSRHREFHADAGSAKLVGREKMIAALQRLKTSYEPQEAGSMMAFCINGKSKTFSELFMSHPPLDKRIEALRSGQYLK
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NA13_ANTMC
Sequence: MNRLIILVVAAVFLGMASAEEDVLKRGFPCRCDSDGPSVHGNPLSGTIWVTSCATGWHKCNSENELFHECCKQG
What is the function of this protein?
Inhibits voltage-gated sodium channels (Nav).
What are the official names of this protein?
Delta-actitoxin-Amc3a, Delta-AITX-Amc3a, Peptide toxin Am III, Peptide toxin Am-3.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type I subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: O16O3_CONST
Sequence: MKLTCMVIVAVLLLTACQLITADDSRGTQKHRTLRSKTKLSMSTRCKAAGKPCSRIAYNCCTGSCRSGKCG
What is the function of this protein?
Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).  This peptide selectively targets Cav2. 2/CACNA1B (IC(50)=160 nM) voltage-gated calcium channels (PubMed:26344359).  When tested in mammals, this toxin displays an analgesic potency similar to MVIIA in a range of acute and chronic pain models in rodents, but has less adverse effects (tremor, diminution of spontaneous locomotor activity and bad coordinated locomotion) compared with identical dosages of MVIIA injected intrathecally.
What are the official names of this protein?
Omega-conotoxin SO-3, SO3.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LECG_PSEAU
Sequence: MGRFLLVTLSLLVMAFFLNGANSCCCPQDWLPRNGFCYKVFNDLKTWDDAEMYCRKFKPGCHLASLHSNADAVEFSEYITDYLTGQGHVWIGLRDTKKKYIWEWTDRSRTDFLPWRKDQPDHFNNEEFCVEIVNFTGYLQWNDDSCTALRPFLCQCKY
What is the function of this protein?
Galactose-binding lectin that binds to and agglutinates erythrocytes in a calcium-dependent manner.
What are the official names of this protein?
C-type lectin galactose-binding isoform, CTL, Venom C-type lectin galactose binding isoform.
What is the protein family that this protein belongs to?
Belongs to the true venom lectin family.
What are the subcellular locations of this protein?
Secreted.
Protein: METK_CUTAK
Sequence: MPTRLFTSESVTEGHPDKIADAISDAVLDAMLTEDSHSHAAVETVVTTGQVMVCGEVTTEAYVDIADIARSRILDIGYDSSSKGFDGASCGVSVAIDAQSPDIAQGVTAAYETRHGSTDLIDSQGAGDQGLMFGYACTETPSLMPLPIDMAHALSLQLTKVRKEGALDYLCPDGKTQVTIRYNEDDKPVAVDTVIVSSQHRAGIDLDATMTPDLRRLVIDPVLERYDLDHKDMRVLVNPTGKFVIGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSGAYAMRWVAKNVVAAGLADRCECQVAYAIGAARPVGFRIDTFGTNHVPETVIERAVGEVFDLRPGAIIADLDLLRPIYSQLVAGGHFGRELPGVTWELTDRAEALAATARL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_PYRAB
Sequence: MKVKVFDLNGQPVDEIELPKVFFTPFRPDLIRRAVIASWTHRIQPQGRDPMAGKRRVTENIGKGHGMARVERLKTPPRYAAFVPFARGGRRTHPPKVEKIIWEGINKKERRLAIMSAIAATANYDIVKARGHIIDNVPQLPLIVVDDLQKVSKTRETREIFKKLGIWDDIERAKEKTGIRAGKGKMRGRRYKKAKGPLIVVGKNEGIVFGARNHPGVDVVVVDNLGVEHLAPGTHPGRLTVWTVSAIERLKEIYG
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: KIN29_CAEEL
Sequence: MAAPRRRMGLEKIGLYDVGRAIGKGNFATVRIARHKIAKTKVAIKSIDVSALDRENLIKLEREVKIVKVIDHPHIVKSYEIMRVDNMLYIVSEYCSSGELYETLIEKGRVAENVARKWFSETASAVAYLHSQGIVHRDLKAENILLGKNSNIKIIDFGFSNFQTGDQLLNTWCGSPPYAAPELLLGNSYDGMKADIWSMGVLLYILVAGGFPFPSDSVNKLKRSVLSGLVKIPYWVSVECADFIRKMLVLNPGKRYTIQNVLQHRWMHIRDDVQKNQAAQLLEAIPSSSIEIRQQSTKLNPTIMMFMQQHGKWSEEQIIDAVLGRDFESPIFATYELLADKVKKGTLEGTGEEFPRRGSRGSILSGKANVDEQPLTPTISAHQLAQLNLSSPDCDSDDSSNSDLCDDSPMSSMGPMNHERQFGTPHGLDIIGNRFENRRHTLCASEQLLSPNMMGQFPPPNLLLNNFSMNPPLGFPPMPEGQAAEFPLPSLHPAFATIPIADLSKMLPVPKSERRASAGETLLPTNFDLTQHLANLPAPPISFPTVEEEGKSYLSKYGGKRNTVHCLGNQLGGGIQNPIPRYQRTPYTKAPPAERRSSWASPSLSAQQQNHLEKLFKQALQTNNDMTRLHKEFKGLSHGCAQSQITNEGSSLACPQISITDEYNRQHNIAPSASSFDPVSIFQKNAQEVVFGQRPATAIGFSSTSFSGMSTPEQTTRSIDDRVRSIVCTLPFTEVIDELKASLNILKIPFSESHEMVYEPQVTEMRRLSLPSGVEIGVAVLPPEHKAHVEFAIINNDSPTSEYLCDQLICRLRMIDPSWSSE
What is the function of this protein?
Regulates chemoreceptor expression by phosphorylating the hda-4 class II histone deacetylase (HDAC) and inhibiting the gene repression functions of hda-4 and the mef-2 transcription factor, enabling the correct sensing and transduction of food signals.  Role in determining body size, the dauer decision and serotonin-mediated egg laying.  May modulate the Sma/Mab pathway and regulates development in the later larval stages.
What are the official names of this protein?
Serine/threonine-protein kinase kin-29.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Nuclear in larval stage. Predominantly cytoplasmic in the adult but translocates into the nucleus following heat shock.