PharMolix/UniProtQA huggingface dataset:
Protein: MANBB_ASPCL
Sequence: MAALQRFPLSKGWSFKDSEDKSEDAWMPVPVVPSVVQQDLQANNKLKDPYIGFNELETRWVNEKSWTYKTTFQKPAVPAGSAIFLAFDGLDTFATVKLDGNVILESDNMFLAHRLDVTKALEAEGDHSLEIDFDCAFLRAKELRKQDSKHNWASFNGDPSRLSVRKSQYHWGWDWGPVLMTAGIWREVRLEVYTARVADLWTDVQLASDHQNAQITAFAEVESVNSDAHKARFTLSLHGQELGREEVSVSEDGSAKVSFDVKSPSLWWPHGYGDATLYEVSVSLVKDQDEVHQVSKKFGIRTAEVVQQPDKHGKSFFFRVNGVDIFCGGSCWIPADNYLPSVTADRYRKWIELMVHGRQVMIRVWGGGNYEDDSFYDACDELGVLVWQDFMFGCGNYPTWPNLLESIRKESVYNVRRLRHHPSIVVWVGNNEDYQVQESAGLTYDFEDKNPENWLKTDFPARYIYEKILPEVVEEYSPSTFYHPGSPWGDGKTTSDPTVGDMHQWNVWHGTQEKYQIFDTLGGRFNSEFGMEAFPHMSTIDYFVENEADKFPQSHVLDFHNKADGHERRIATYLVENLRTATDLETHVYLTQVVQAETMMFGYRGWRRQWGDERHCGGALLWQLNDCWPTISWAIVDYFLRPKPAFYAVARVLNPIAVGVRREHHDWSVTHAQPPKTSKFELWVASSLQKEVQGTVELRFLSINTGLEVRERIVHENVSIVPNGTTNLIVDGLIDYKVHPEPHVLAVRIWVNGELVARDVDWPQPFKYLDLSNRGLEVKLVSESENEQTLLLSAQKPVKCLVFEEREGVRISDSAIDIVPGDEQRVTIKGMKPGDAPLKYKFLGQ
What is the function of this protein?
Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of beta-mannosidic oligosaccharides of various complexity and length.  Prefers mannobiose over mannotriose and has no activity against polymeric mannan.  Is also severely restricted by galactosyl substitutions at the +1 subsite (By similarity).
What are the official names of this protein?
Beta-mannosidase B, Mannanase B, Mannase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family. Beta-mannosidase B subfamily.
Protein: RISB_METBF
Sequence: MTISLGFVVAEFNRDLTYQMELLGREHAEFLGATVKETILVPGVFDMPLAIKKLCQRDDIDAVVTIGSVIEGDTDHDQVVMQHAARKIMDLSLEFNKPVTLGIPGPGMTRMAAHERVDYAKRAVEAAVKLVRRL
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: QUEF_ACIBS
Sequence: MSVEQSLLGKETQYPTSYQPDVLFPIARAQSREKYAHIQGITQGKDWWHVFEISWLNAHGIPQVAIGRITLPASSPNLIESKSLKLYFNSLNFTQFDSTQSFIETVEKDLSAAAGAKVELTLFQVDDLETSKPQGICIDDLMPERLEQHPDATLLKLDESGEEIEVELYSHLLRSNCPVTSQPDWGTVFIRFKGKKPCYRSLLAYIISYRQHNGFHEQCVEQIFADIWQNLQPEKLMVYATYTRRGGLDINPCRVSDLTWMPKPIRLARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y385_LISMF
Sequence: MGRKWANIKEKKASKDKTNSRIYAKFGIEIYVAAKSGDPDPHANQKLRFVIERAKTYNVPKHIIDRAIEKAKGTGDETYSELRYEGFGPNGSMIIVDALTNNVNRTASDVRAAYSKNGGNMGVSGSVAYMFDNTAIFGVEGKDADELLELLMEVDIDVRDILDEDGQAIIYAEPEDFHKVQEGLKAAGIEEFTVAEIEMIPQNDIQLSGEDLEKFEKLIDALEDLEDVQKVYHNVELED
What are the official names of this protein?
Probable transcriptional regulatory protein LMOf2365_0385.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family. YeeN subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPPA_BACTN
Sequence: MLGNLDKYQIILASNSPRRKELMSGLGVDYVVRTLPDVDESYPADLAGAEIPEYISREKADAYRSIMQPGELLITADTIVWLDGKVLGKPEGREGAVEMLRSLSGKSHQVFTGVCLTTTEWQKSFTAASDVEFDVLSEEEIRYYVDKYQPMDKAGAYGVQEWIGYIGVKSISGSFYNIMGLPIQKLYGELKKL
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DS13B_MOUSE
Sequence: MDSLQKQELRRPKIHGAVQVSPYQPPTLASLQRLLWVRRTATLTHINEVWPNLFLGDAYAARDKGRLIQLGITHVVNVAAGKFQVDTGAKFYRGTPLEYYGIEADDNPFFDLSVHFLPVARYIRDALNIPRSRVLVHCAMGVSRSATIVLAFLMIFENMTLVDAIQTVQAHRDICPNSGFLRQLQVLDNRLRRETGRL
What is the function of this protein?
Dual specificity phosphatase that dephosphorylates MAPK8/JNK and MAPK14/p38, but not MAPK1/ERK2, in vitro (By similarity).  Exhibits intrinsic phosphatase activity towards both phospho-seryl/threonyl and -tyrosyl residues, with similar specific activities in vitro (PubMed:10585869).
What are the official names of this protein?
Dual specificity protein phosphatase 13 isoform B, DUSP13B, Dual specificity tyrosine phosphatase TS-DSP6, Testis- and skeletal muscle-specific DSP.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Protein: MTGA_PECAS
Sequence: MRWSRGRGGGLLTWLKRLIVRSVLVVIGAWLAGILLFSFLPVPFSAVMVDRQVSAWLKGEFAYVAHSDWVAMDDIAPAMALAVMAAEDQKFPQHWGFDVDAIGQALKHNERNTQRVRGASTLSQQMVKNLFLWDGRSWVRKGLEAGITTGVELVWTKRRIITVYLNIAEFGPGVFGVEAAARRYFNKSASKLTASESALLAAVLPNPIRFRANAPSGYVIQRQQWILRQMRQMGGDAFLRDNNLN
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MDH_DESAP
Sequence: MRRKKISIVGAGNVGATCAHWIAAKELGDIVLLDVAEGVPQGKALDLMEAAPVEGFDCMITGTNDYRDTAGSDVAVITAGVARKPGMSRDDLVSINVKIVRQAAAEIARYSPDALIIVVTNPLDVMCYVAYKASGLPRGKVFGMSGILDGARFRTFVALELGISFEDVTTLVLGGHGDHMVPLVRYTYAGAIPVEKLIPADRLAELVQRTRQGGAEIVELLKTGSAYYAPGAAITQMLEAVLKDKKRILPCAAYLDGEYGHRDICAGVPTIVGAGGIERIIELELTAEEQAAFDRSVSAVRGVLKGLDI
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: QUEF_CAMLR
Sequence: MRYGEKEIKEFDVENMEVWPNDAKNDYVIKITLPEFMCCCPRSGYPDFATIYLEYIPNKLVVELKAIKLYINTFMYRNVSHEASINEIYNTLKEKLDPKWIKVVGDFNPRGNVHTVIECRSDLVVPQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIBA_MOUSE
Sequence: MLSLRVTCLILSVASTVWTTDTEDKGEFLSEGGGVRGPRVVERHQSQCKDSDWPFCSDDDWNHKCPSGCRMKGLIDEANQDFTNRINKLKNSLFDFQRNNKDSNSLTRNIMEYLRGDFANANNFDNTYGQVSEDLRRRIEILRRKVIEKAQQIQALQSNVRAQLIDMKRLEVDIDIKIRSCKGSCSRAVNREINLQDYEGHQKQLQQVIAKELLPTKDRQYLPALKMSPVPDLVPGSFKSQLQEAPPEWKALTEMRQMRMELERPGKDGGSRGDSPGDSRGDSRGDFATRGPGSKAENPTNPGPGGSGYWRPGNSGSGSDGNRNPGTTGSDGTGDWGTGSPRPGSDSGNFRPANPNWGVFSEFGDSSSPATRKEYHTGKAVTSKGDKELLIGKEKVTSSGTSTTHRSCSKTITKTVTGPDGRREVVKEVITSDDGSDCGDATELDISHSFSGSLDELSERHPDLSGFFDNHFGLISPNFKEFGSKTHSDSDILTNIEDPSSHVPEFSSSSKTSTVKKQVTKTYKMADEAGSEAHREGETRNTKRGRARARPTRDCDDVLQTQTSGAQNGIFSIKPPGSSKVFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNDYLHLLTLRGSVLRVELEDWAGKEAYAEYHFRVGSEAEGYALQVSSYRGTAGDALVQGSVEEGTEYTSHSNMQFSTFDRDADQWEENCAEVYGGGWWYNSCQAANLNGIYYPGGTYDPRNNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLVGQ
What is the function of this protein?
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.  Fibrin has a major function in hemostasis as one of the primary components of blood clots (PubMed:7649481).  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization (PubMed:11389004).  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood (PubMed:7649481).  However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo (PubMed:10930441).  Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway (PubMed:19332769).  Maternal fibrinogen is essential for successful pregnancy (PubMed:7649481).  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage (PubMed:12629066).  May also facilitate the immune response via both innate and T-cell mediated pathways (PubMed:23487423).
What are the official names of this protein?
Fibrinogen alpha chain.
What are the subcellular locations of this protein?
Secreted.
Protein: PUM10_ARATH
Sequence: MEIFNFGQASDHRRLPDFGSGGFLQSLDTNPFLKNQYYNNSVEALELCKKLNKMGISCDMSIWTKPEEPFRVDPGDFGAKTLHESFGFDQNLTGASQIHDGFRNFSSVRVQNNNFHGVSPSPGLLGLQDSFNPNGFEEMMAFKDHKDFLLDHINEPIKRSPFLRGNDAFKGSLMFEGIRVSQILAAMEGSGASYPDEPKINGGLPLDLVSMVEIYGSVNLMARDQIGCRALQKLVEEGTVLDSKVIFLEIIDHVVELSMDPLGNYIVQKLLVVSDEEQRTMIVSVLTSKPRELIKICLNTNGTRVIQKMIKTVKTKQQIALVKSALEPGFLVLVNDSNGYHVLQSCLEFLVPNDNKFVVEAATEYCAQLATHQYGCYVLQCSLINTVGLQHERLVAEISRDSLRLSQDPFGNYVVQCLIDQQVSSVNLLLPFRTHCIELATQKFSSHVIEKCLRKYPESRAEIVRELLSYPNFEQLLQDPYANYVIQTALSVTKGAVRARLVEKVKRFGKLQSNPYCKKIFSKTILKK
What is the function of this protein?
Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.
What are the official names of this protein?
Putative pumilio homolog 10, APUM-10, AtPUM10.
Protein: ATG26_ASHGO
Sequence: MLKGQKEGEAEPVPEGDKSGAGSSPSGVRKGLRVPLGLVSHSFSSLAKHKEAERRLTDEEESLSSPQDREDDAASPNIMAKSIAGLLTTASMYVGIGDIHRAEQLATGQPETDAGADETEDEMDEAGDETGDDADAPATGTDGEEESRPVSAQESRRSTLFELSIEPHPESHTAQASRTKNRRSRMTSKLRSKFNLDDDEELVREYPCWLLRDVLIQGHIYLTSRNLLFFAFLYKSNGSARLTGNLSICNNGLSISGISGKPTRYWTVLKDHTLSLYSSSTDLYFPVLTIDLRYVTKVQHCKNNGKDTRQFHITTESKTYTFYSDNEHSARSWSSALKKQVFATQNSDNDSMSVRIPLSNIIDVEEQAIVEQGLTLRVRVMESSDSFALDDYFFMFFNNAGSQLKELIQIQVANLEMLGAANVDYARHPLPPDTEASLPAVASDAAPQDAAIASEAAADAAAADTASHSPSTNAEPRARGRSTERAMAASAYLFGRLTSPRRDDAKQLSPSKVKLRFRSVADTLKLTTPRQPGSDAPQEPEPETTILESRPRLNYWSPRPFTTMRSMWNAQPVHYAAKGMSLFADDDELMIGDEAELLAADKRFKAHFSLTDDESLVASYYTYLNRSMPLYGKIYLGKTIMCFRSLLPGSKTKMILPLHDVENCYKEQGFRFGYFGLVVVIYGHEELFFEFASQKSRDDAEYVILKIIDSLKPVDGVMADDMSAGAYSLKAAQGRDATTDAKVKLFEQRISSVGYDIPIMVEDNPFYKTTITPKKFYTFGMLTIGSRGDVQPYIALGKGLLQEGHRVVVISHAEFGDWVRSHGLQFRAIAGDPAELMALMVQHGSMNVGLIREAASTFRNWIRDLLETAWEACQGIDVLIESPSAMAGIHIAEALQIPYFRAFTMPWTKTRSYPHAFIVPDQKRGGNYNYFTHVLFENIFWKGINSQVNRWRVEKLGLKKTNLEFMQQGKVPFLYNMSPTVFPPSVDFAEWIKVTGYWFLNESSNYVPPQALLEFMAKARRLDKKLVYIGFGSIVVKDPVKMTMAVVEAVVKADVYCILNKGWSARLGGQSQKSIEVQLPNCVYDAGNVPHDWLFPRVDAAVHHGGSGTTGATMRAGVPTVIKPFFGDQYFYANRIEDIGAGIALRKLNACTLSRALKEVTTNTRIIAKAKKIGQDISKEDGVATAIAFIYSEMAYAKSLIKAKRQEDKKAAKEAKQIQNEDSWLLL
What is the function of this protein?
Probable sterol 3-beta-glucosyltransferase that is not involved in cytoplasm to vacuole transport (Cvt), pexophagy or nonselective autophagy (By similarity).
What are the official names of this protein?
Sterol 3-beta-glucosyltransferase, Autophagy-related protein 26.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: LAN1A_RUMFL
Sequence: MNKNPIYRSEEEAKDIACGNVAAELDENSQALDAINGAGWKQTIVCTIAQGTVGCLVSYGLGNGGYCCTYTVECSKTCNK
What is the function of this protein?
Lanthionine-containing peptide antibiotic (lantibiotic) only active on Gram-positive bacteria in synergy with Flvbeta peptides, which are encoded by the same operon than Flvalpha. a (PubMed:27028884).  Shows antibacterial activity in synergy with Flvbeta. b, Flvbeta. c, Flvbeta. e and Flvbeta. g (PubMed:27028884).  Does not show antibacterial activity when tested with Flvbeta. a, Flvbeta. d, Flvbeta. f and Flvbeta. h (PubMed:27028884).  The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores (By similarity).
What are the official names of this protein?
Lantibiotic Flvalpha.a.
What are the subcellular locations of this protein?
Secreted.
Protein: DCN1_CAEEL
Sequence: MNRLKSDQKTKLRQFVQWTQVTEAVSLNFLAKANWNIEYAMTLYFDNPNLFAGSTPQPSVDRSNIERLFNQYVDPKDKVGEKRMGPHGINRLLTDLGYEATDRRVLVLAWKFTAQTQCEFSLDEWVKGMTALQADTVQNLRQRIDSINSGLESDKAKFHELYLFAFNYAKSAACRNLDLETAICCWDVLFGQRSTIMTQWIDFLWAQENAAASRLAQNVGASNAKQFKSVWISRDTWNLFWDFILLSKPDLSDYDDEGAWPVLIDQFVDYCRENLNYPKPGNASNDQQMETPSYY
What is the function of this protein?
Required for neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes.  Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.  Does not act by preventing deneddylation, but rather facilitates neddylation, possibly by acting with rbx-1 to recruit the Nedd8-charged E2 enzyme to the cullin component of SCF-type complexes.
What are the official names of this protein?
Defective in cullin neddylation protein 1.
Protein: KDPA_ECOSM
Sequence: MAAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTTGVERVLFSALGVSDREMNWKQYLSAILGLNMLGLAVLFFMLLGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFAFIRAFTRQSMSTLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFLPYQAVNTVEGAKQLLPMGPVASQEAIKMLGTNGGGFFNANSSHPFENPTTLTNFVQMLAIFLIPTALCFAFGEVAGDRRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGADSSINMEGKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGRTPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKSQPASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NQRE_HAEI8
Sequence: MEHYISLFVKAVFIENMALSFFLGMCTFLAVSKKVSTAFGLGIAVTFVLGIAVPVNQLIYANVLKENALIEGVDLSFLNFITFIGVIAGLVQILEMVLDKFMPSLYNALGIFLPLIAVNCAIFGGVSFMVQRDYNFPESIVYGFGSGLGWMLAIVALAGLTEKMKYADIPAGLKGLGITFISVGLMALGFMSFSGIQL
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit E, Na(+)-NQR subunit E, Na(+)-translocating NQR subunit E, NQR complex subunit E, NQR-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LPXK_ALISL
Sequence: MIEKIWFDNHILGKLMWPLLWPLSCLFKYVANKKKLDYFTGKKTAYKSSVPVVVVGNITAGGNGKTPVVVWLVEQLQLQGMKVGVASRGYGGKAPHYPYLLSNTTTPDISGDEPVLIKQRTKAHVAVAPVRSEAVKMLEEQGVDIVITDDGLQHYALQRDVEFIVIDGKRRFGNQAFIPLGPLREGLDRLASVDFLICNGEQPKTNEIAMTLEPSKAVNLVTGEKKSVSNLGELVAFAGIGHPPRFFDTLASLNADVVHTQGFVDHKAFEPEEIKNLMQYGEQLIMTEKDAVKCQSFAESSWWYLPVDASFPEEKAQQILNKIIEVKEQYGLSSS
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: LEPA_PSEPG
Sequence: MSHIRNFSIIAHIDHGKSTLADRFIQMCGGLSAREMEAQVLDSMDLERERGITIKAHSVTLHYKAQDGKTYQLNFIDTPGHVDFTYEVSRSLAACEGALLVVDAGQGVEAQSVANCYTAIEQGLEVMPVLNKMDLPQADPDRVKDEIEKIIGIDATDAVACSAKSGMGVDEVLERLVHTIPAPEGEIDAPLQALIIDSWFDNYLGVVSLVRVRHGRVKKGDKILVKSTGKVHLVDSVGVFTPKHTQTADLKAGEVGFIIASIKDIHGAPVGDTLTLSSTPEVEVLAGFKKIQPQVYAGLFPVSSDDFEDFRDALQKLTLNDSSLQYMPESSDALGFGFRCGFLGMLHMEIIQERLEREYDLDLITTAPSVIYELELKTGETIVVDNPSKLPDVSSVTDFREPIVTATILVPQEHLGNVITLCIEKRGVQRDMQFLGSQVQVRYDMPMNEVVLDFFDRLKSTSRGYASLDYHFDRYQSANLVKLDVLINGDKVDALALIVHRDNAAYKGRALTEKMKELIPRQMFDVAIQAAIGGQIIARTTVKALRKNVLAKCYGGDVSRKKKLLEKQKAGKKRMKQVGNVEIPQEAFLAVLRLDS
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: EST2A_MOUSE
Sequence: MPLARLPGWLCVVACGLLLLLQHVHGQDSASPIRNTHRGQVRGSFVHVKDTKSGVHAFLGIPFAKPPVGLLRFAPPEDPEPWSGVRDGTSQPAMCLQPDIMNLEDAKEMNLILPPISMSEDCLYLNIYTPTHAQEGSNLPVMVWIHGGGLVVGSASMNDVSKLAATEEIVIVAIQYRLGVLGFFSTGDQHARGNWGYLDQVAALRWVQKNIAYFGGNRDRVTIFGVSAGGTSVSSHILSPMSKGLFHGAIMQSGVALLPDLISDTSEVVYKTVANLSGCEATDSEALIHCLRAKSKQEILAINQVFKMIPAVVDGEFLPKHPQELLTSMDFHPVPSIIGVNTDECGWGVPMFMGLDHIIKNITRETLPAVLKNTAARMMLPPECSHLLVEEYMGDTEDPETLQAQFREMLGDFMFVIPALQVAHFQRSQAPVYFYEFQHLSSFIKHVRPSHVKADHGDDVAFVFGSYLWDMNLDLTEEEELLKRMMMKYWANFARNGNPNSEGLPSWPVLDHDEQYLQLDTQPAVGRALKARRLQFWTKTLPQKIQELKGSQDKHAEL
What is the function of this protein?
Carboxylesterases that catalyzes the hydrolysis of pyrethroids pesticides.  Hydrolyzes permethrin faster than cypermethrin.  Hydrolyzes retinyl esters (By similarity).
What are the official names of this protein?
Pyrethroid hydrolase Ces2a, Carboxylic ester hydrolase 2A, carboxylesterase 2A.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Microsome.
Protein: ISCA_YERP3
Sequence: MSISISDSAAQRVSAFLNHRGKGLGLRLGVRTSGCSGMAYVLEFVDEINDDDIVFEDKGVKVIIDGKSMVYLDGTELDFVKEGLNEGFKFNNPNVSNECGCGESFNV
What is the function of this protein?
Is able to transfer iron-sulfur clusters to apo-ferredoxin.  Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically.  Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.
What are the official names of this protein?
Iron-binding protein IscA, Iron-sulfur cluster assembly protein.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: LEUC_GEOSL
Sequence: MGKTIAEKIFASHLVDEPFAGTKVLRLDVVMCHEITTPIAIADLMARGKDRVFDPTKIKAVIDHVTPSKDSKTATQAKMLRDWARRHGIVDFFDVGANGVCHALFPEKGFIRPGYTVIMGDSHTCTHGAFGAFAAGIGTTDLEVGILKGVCAFREPKTIRINLNGSLPEGVYAKDVILHVIGRIGVNGATDRVMEFRGSVVDTMTMESRMTLCNMAIEAGGTSGICMPDMVTVDYLWPFLKDEYQSREAALAAFSLWRSDEDAVYEQVLDFDVSSLEPIVTFGYKPDQVKPVSEIAGTPVDQVYLGSCTNGRLEDLRIAARILKGKKIAPTVRGILSPATPKIYQDAMREGLIDIFMEAGFCVTNPTCGACLGMSNGVLAEGEVCASTTNRNFMGRMGKGGMVHLMSPATSAATAIEGKIADPRKYL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: BAMA_NEORI
Sequence: MVWLLFLSSFCFADEVVEIRISGNKRVSETTVRGLLHVEVGQDVASDELNAVFKRLTASRLFSSVELDLTAGILEVKLQENPILRNVVVKGNKLLSRAAIDKILVYKKDAIFDVHEFENSITALKSYYRDSVVEKTAISYRIVPIDENNVDVEVTVKEAKPTVIRAIEFEGNTTYSDRVLKHVIRSREKSILRLFGTAHYYSREKLEFDKDLLADFYQGKGYFDYALEGLEERENEDGVVLVFKLKEGARYSFGRVSVVSEKGEIEISDLKEKVRIREGAVFNIGAVRENALTLLSVLNERGHMFVNVVPEYHPDANGRVDLTYHVVSTKKYRIRKINISGNTRTKDTVIRREMLLSENDLYQPSKVADSRRRILNLGFFDEVYIEEHKIDGQNLILEVRVKERPTGTLNLSGGYGSDVGFFGNFSFVENNLFGTSDRLVVELQKASLGSNYSMEFQRKRIFDTFITAGASVFYKNRNEKANGLYKFSSVGGDGSVSYSLRDDLRLHLGYSLSFDKIFDVEGDAPESVKSSAGTKILSAVSYSLFLNKLDNYFVPRYGYGVRFGNKFAGIGGDVKFLRSDFKAGGFVSVFDQSAVLSLIVRAGNIFGYSGQGVDVANRFFLNEMRGFDNLGIGPRDVETDDALGGNFFILGTAEVQVPMRLPVELDLKAAFFYEVGTLTGVDVTTEKVYDSHALRSSVGAGLVWNSPFGVLRVDVAKALVEGKGDKVKTVKFGIVSPF
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
What are the official names of this protein?
Outer membrane protein assembly factor BamA.
What is the protein family that this protein belongs to?
Belongs to the BamA family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: CTU1_LODEL
Sequence: MVESSNTKKVKVSSLCELCHGRKAVMKRPKNLRKLCKECFFHVFETEVHNTIVENKLFANVENSEFPERRAVAIGASGGKDSTVLASVMKTLNERYNYGLKLVLLCIDEGIKGYRDHSLETVKMNQKEYDMPLEILSYKDLYDWTMDEVVSCAGIRSSCTYCGVLRRQALDKGAEKLGINHIVTGHNADDMAETVLLNLLRGDINRIENSTKIITDSENSVIQRSKPFAYMSQKEIVLYAHYKNLTYFSTECTYSEEAFRGECRSLFHSLSAVLPSVHTNTIYSGQQFKRKAKAMKRQNNKNNKNNKNNMADEHEVLPNGTVAIKESKRCKKCGSLASNDLCQACFLLAGLEVSRAKVSIDSEGDGAAKLSKTLEGLTF
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation.  It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  May also be involved in protein urmylation.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 1, Cytoplasmic tRNA adenylyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.