PharMolix/UniProtQA huggingface dataset:
Protein: H2AY_HUMAN
Sequence: MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEILELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGSKGKLEAIITPPPAKKAKSPSQKKPVSKKAGGKKGARKSKKKQGEVSKAASADSTTEGTPADGFTVLSTKSLFLGQKLQVVQADIASIDSDAVVHPTNTDFYIGGEVGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIGIYVQEMAKLDAN
What is the function of this protein?
In contrast to isoform 1, does not bind poly-ADP-ribose (PubMed:15902274).  Represses SOD3 gene expression (PubMed:23022728).
What are the official names of this protein?
Core histone macro-H2A.1, Histone macroH2A1, mH2A1, Histone H2A.y, H2A/y, Medulloblastoma antigen MU-MB-50.205.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
Protein: YIHI_ECOK1
Sequence: MKPSSSNSRSKGHAKARRKTREELDQEARDRKRQKKRRGHAPGSRAAGGNTTSGSKGQNAPKDPRIGSKTPIPLGVAEKVTKQHKPKSEKPMLSLQAELELLETDERLDALLERLEAGETLSAEEQSWVDVKLDRIDELMQKLGLSYDDDEEEEEDEKQEDMMRLLRGN
What is the function of this protein?
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function.  May play a role in ribosome biogenesis.
What are the official names of this protein?
Der GTPase-activating protein YihI.
What is the protein family that this protein belongs to?
Belongs to the YihI family.
Protein: CSN5_ASHGO
Sequence: MDTPSAALHRHTVGQLRKLLLHREGSAGCGRLQPALDGSQPLDSPLSTVPSSRSQVRVQQELWKQDPTYFQKAALSALACMKILRHAFDGGDMEVLGMLLGYVQDEMIVVVDSYRLPVEGTETRVNAQMESYEYTVQYLETAVPEGLAIVGWYHSHPGYGCWLSGIDAETQTLNQNFQDPYLAIVVDPKRSKASGVIDIGAFRTMPETADTRSVSSHSNASRYGHHSARYYELEVSYFEVPQERRWCDSRLSVEPPKPADATERAMLAQLLEAAKACKNVKRLQTVDRALVPESIGPYALREQADQDLQFRRPLRSFSSNSIARRSSTEVALGNANEELDPLPTLADANLRNHDSPSADMAMDNTSISSNEEQPHLTFQESSGVQLNAAETEYFDIKNELLTLKLLEYQKARFYRDAFTL
What is the function of this protein?
Catalytic component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes.  The CSN complex is involved in the regulation of the mating pheromone response.
What are the official names of this protein?
COP9 signalosome complex subunit 5.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family. CSN5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RPOC_FLAPJ
Sequence: MMENRNNNNNRDKNPVKRFNKISIGLASPESILAESRGEVLKPETINYRTHKPERDGLFCERIFGPVKDFECACGKYKRIRYKGIVCDRCGVEVTEKKVRRDRVGHINLVVPIAHIWYFRSLPNKIGYILGLPSKKLDMIIYYERYVVIQAGIAQNAEGESIKRLDFLTEEEYLNILDTLPADNQYLDDFDPNKFVAKMGAECIMDLLARINLDELSYDLRHKANNETSKQRKTEALKRLQVVESFRESNKNRENRPEWMIMKVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVIIRNNRLKRLMEIKAPEVILRNEKRMLQESVDSLFDNTRKASAVKTESNRPLKSLSDSLKGKQGRFRQNLLGKRVDYSARSVIVVGPELRLFECGIPKDMAAELYKPFVIRKLIERGIVKTVKSAKKIIDKKEPVVWDILENVIKGHPILLNRAPTLHRLGIQAFQPKLIEGKAIQLHPLVCTAFNADFDGDQMAVHLPLGPEAILEAQLLMLASHNILNPANGAPVTVPSQDMVLGLYYMTKERLTTEGHIILGQDLVFYSAEETNIALNEGRVELNARVKIRAKDFNEEGELVYKIIQTTAGRVLFNEVVPEAAGYINDVLTKKNLRDIIGKILAVTDVPTTAAFLDNIKDMGYKFAFKGGLSFSLGDIRIPEQKTQLIADARAQVEGISGNYNMGLITNNERYNQVIDIWTSANAQLTELAMKNIREDQQGFNSVYMMLDSGARGSKEQIRQLTGMRGLMAKPKKSTAGGGEIIENPILSNFKEGLSILEYFISTHGARKGLADTALKTADAGYLTRRLHDVSQDVIVNIEDCGTLRGVEVSALKKNEEIVESLGERILGRVVLQDVVNPLTNDILVHAGEQITEAIMKVIENSPVEKVEVRSPLVCEATKGICAKCYGRNLATGKMTQRGEAVGVIAAQSIGEPGTQLTLRTFHVGGVAGGISEESNILAKFAGRLEIEDLKTVKGEDGEGNLVDIVISRSTEMKLIDQKTGILLATNNIPYGSSIYVNDAQVVEKGDVICKWDPYNGVIVSEFTGKIAYEDLEQGQSFMVEIDEQTGFQEKVISEGRNKKLIPTLLVYGKNDELIRSYNLPVGAHLMVNDGEKIKAGKILVKIPRRSSKTGDITGGLPRITELLEARNPSNPAVVSEIDGVVSFGKIKRGNREIVIESKFGEIKKYLVKLSSQILVQENDFVRAGVPLSDGAITPDDILRIQGPAAVQQYLVNEIQEVYRLQGVKINDKHFEVVIRQMMRKVRVQDPGDTLFLEDQLIHTKDFIVENDKLYGMKVVEDSGDSSNLKAGQIITPRELRDENSLLKRTDKNLVIARDVITATATPVLQGITRASLQTKSFISAASFQETTKVLNEAAVAGKIDYLEGLKENVIVGHRIPAGTGMREYDHTIVGSKEEYNDLMVAKEEFNY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: SILIC_PETFI
Sequence: MAIVYGAILFQIILIACAEFPPEWHAWKATHSISYESEHEERRRHVVWQQNQEYIDQHNKYKEQFGYTLEMNKFGDMSNAEFAELMMCVQDYNHHGNLTESLLADNKFKGRVREYQAPATVSLPETVDWRTGGAVTHVKDQLRCGCSYAFAAVGALEGAAALARGRTASLSEQNVLDCSVPYGNHGCSCEDVNNAFMYVIDNGGLDTTSSYPYVSRQYYCKFKSSGVGATATGIVTISSGDESSLESALATAGPVAVYIDASHSSFQFYKYGVLNVPNCSRSKLSHAMILIGYGTTSSKKYWLLKNSWGPNWGISGYIKMSRGMSNQCGIATYASFPTL
What is the function of this protein?
Polymerizes silica around the axial filament during spicule formation.
What are the official names of this protein?
Silicatein.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
Protein: SYH_MYCCT
Sequence: MLQKPRGTQDFFLDETKLWIKVETKLREILNKFNYSEIRTPMFESKELFIRSIGSTSDIVSKEMYEFVDKKNRSLVLKPEGTASVVRAVVENKLYAEDYLPFKTYYISPMFRYERPQNGRYRQFHQLGIEVYGSDSIQQDYEVLNIANNIINDFKLNKNIKIYTNYLITGKNREQYILELKKYLTDFKLCNDCNIRIEKNPLRVLDCKIDDKQFNNVPSMKDFLTDEEQKRYQQTLDLFKEMNISTIHDDKLVRGLDYYTGFIFEIKYEAKNIEQTIIAGGRYNNLVYEIGNINLPACGFGMGLERFINIIKEQNNKLNKNDQSIDLYTICLDQSAIKLNQQILELSRSIGLISDSNYYNMSLKSALKKSDKLNPKYLIILGEKEATSNQFIIKNKINKTEIKTTLTNFVNDLK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBRL1_ARATH
Sequence: MRPPVTGGRGGGGFRGGRDGGGRGFGGGRSFGGGRSGDRGRSGPRGRGRGAPRGRGGPPRGGMKGGSKVIVEPHRHAGVFIAKGKEDALVTKNLVPGEAVYNEKRISVQNEDGTKVEYRVWNPFRSKLAAAILGGVDNIWIKPGAKVLYLGAASGTTVSHVSDLVGPEGCVYAVEFSHRSGRDLVNMAKKRTNVIPIIEDARHPAKYRMLVGMVDVIFSDVAQPDQARILALNASFFLKTGGHFVISIKANCIDSTVAAEAVFQSEVKKLQQEQFKPAEQVTLEPFERDHACVVGGYRMPKKQKTPAS
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins (Probable).  Involved in pre-rRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA (Probable).  Site specificity is provided by a guide RNA that base pairs with the substrate (Probable).  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA (Probable).  Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (By similarity).  Binds monophosphate phosphoinositides in vitro (PubMed:29163603).
What are the official names of this protein?
rRNA 2'-O-methyltransferase fibrillarin 1, AtFbr1, AtFib1, Fibrillarin-like protein 1, Histone-glutamine methyltransferase, SKP1-interacting partner 7.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Localizes to the fibrillar region of the nucleolus.
Protein: KPCL_MOUSE
Sequence: MSSGTMKFNGYLRVRIGEAVGLQPTRWSLRHSLFKKGHQLLDPYLTVSVDQVRVGQTSTKQKTNKPTYNEEFCANVTDGGHLELAVFHETPLGYDHFVANCTLQFQELLRTAGTSDTFEGWVDLEPEGKVFVVITLTGSFTEATLQRDRIFKHFTRKRQRAMRRRVHQVNGHKFMATYLRQPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHHLIVTACTCQNNINKVDAKIAEQRFGINIPHKFNVHNYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNCGVNAVELAKTLAGMGLQPGNISPTSKLISRSTLRRQGKEGSKEGNGIGVNSSSRFGIDNFEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQDDDVECTMTEKRILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHEKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTKNPTMRLGSLTQGGEHEILRHPFFKEIDWAQLNHRQLEPPFRPRIKSREDVSNFDPDFIKEEPVLTPIDEGHLPMINQDEFRNFSYVSPELQL
What is the function of this protein?
Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells.  In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentiation.  Associates with the cyclin CCNE1-CDK2-CDKN1B complex and inhibits CDK2 kinase activity, leading to RB1 dephosphorylation and thereby G1 arrest in keratinocytes.  In association with RALA activates actin depolymerization, which is necessary for keratinocyte differentiation.  In the pre-B cell receptor signaling, functions downstream of BLNK by up-regulating IRF4, which in turn activates L chain gene rearrangement.  Regulates epithelial tight junctions (TJs) by phosphorylating occludin (OCLN) on threonine residues, which is necessary for the assembly and maintenance of TJs.  In association with PLD2 and via TLR4 signaling, is involved in lipopolysaccharide (LPS)-induced RGS2 down-regulation and foam cell formation.  Upon PMA stimulation, mediates glioblastoma cell proliferation by activating the mTOR pathway, the PI3K/AKT pathway and the ERK1-dependent phosphorylation of ELK1.  Involved in the protection of glioblastoma cells from irradiation-induced apoptosis by preventing caspase-9 activation.  In camptothecin-treated MCF-7 cells, regulates NF-kappa-B upstream signaling by activating IKBKB, and confers protection against DNA damage-induced apoptosis.  Promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria.  Phosphorylates ATF2 which promotes its nuclear retention and transcriptional activity and negatively regulates its mitochondrial localization.
What are the official names of this protein?
Protein kinase C eta type, PKC-L, nPKC-eta.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associates with cell membrane during keratinocytes differentiation.
Protein: SYL1_SACS2
Sequence: MYSDFFNSIAFKWQAEWEKSKVFETNMDYSKPKFFITVPFPYTNSPMHVGHGRTYITADIYARYLRMKGYNVLFPFAFQFTGTPVLAIADSIRRGEVDVIEFFKNVYEVPQDKIKELEDPYKLAEYFKEEMKNTAKSIGMSIDWRRTFTTTDPRFEKFIHWQLGKLKELGYLVTEDDVVGYCPNDGFPVGMHDTRGDIEPEITTMNVIMFEGSDSYNFMVATSRPELIFGVVALMVNHDANYVVVEYEGKNFIISEKAYKKLSFQKNMKLVKTITTSDIVKLYAINPITGRKLEIIKNKYVDPSLGTGVVMSYPAHDPFHYLAMTETNKEFEVIPVVETEELDEIPGESAVLQTKNPYALKDFMESIYKTEYYKGYMKDIILSLVPDFLKQYVKENIVGKQVQEARKNTIELLKSLNIYDTIYEISNGPIYCRCGSEIVPKRIKDQWFIAYDNPKWKASALKAINNIELIPNPTKTELEKIVFNARKEPIGRSRGIGVKLPWDESQIVESLSDSTLYTLLYTVIYKMPINIEKEIFDFIFLGKGDAKELERKYGTDLIQLREEFLYWYPVDQRHTGRDLIQNHIPFYIYNHLAIFGEKYLPKRIVINGFVRVGGRKMSKSLRNIYTLSKAIKEFGVDPVRIALTSTSDLLQDLDFNENLVNPIAEQLKKIYDLIDRLLSINTEIKELRTADEWISSKVRDIIEKVNNNITSFKYRDAVNLLLYEIYEILRDYFDLVEIPNQEVIRKILSIWIRALAPFVPHIAEELWHKISSTFVSLEKYPEPNELNLYPDAILEISYINKIIENVRELEDIVHKKAEKVIIYINESEKVKELMKNAIKAVNEEIPLREFTANTEDKIAEKVYVVVSKLDKAIRDYLLNNEIDEEQIIVKNMNFLLRRLGVSEIVIYNAEDPTVPDVKGKKSQALPLSPAIVVE
What are the official names of this protein?
Leucine--tRNA ligase 1, Leucyl-tRNA synthetase 1, LeuRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y899_CYAP4
Sequence: MTQGQGFGFGLGKMKELAAAIQKAQQVQEGAKKLQEDLEKMEIEGVAAGGLVKVIMSGNQEPRRVEISPDLMSEGAEVVADLVTAAMKDAYLKSTTTMRERMEELTGGLSLPGM
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Cyan7425_0899.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: FWDC_METMP
Sequence: MNELILNLKGDVSVPVEMDKILPEKIQEMSLEEISGIELIQGNKTAKVSEIFDVELKESDVAKVTINNCCKKVKRIGEKMTSGEIVVNGDAGMYIGVEMKGGKITVNGDAESWVGQNLKGGEIIINGNAENYVGSAYRGDWRGMSGGKITITGNAGSELGEYLKGGTIVIKGNTKIMPGIHQNGGMIIIEGDIEGRAGGEMMKGAIVVYGKILEPLPSFKFEGIVEDPLVKLSKKDAGTQLKGTFIKFSGDYVNTKPKGQLYAAIENNKNLI
What is the function of this protein?
Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR).  This enzyme is oxygen-labile.
What are the official names of this protein?
Tungsten-containing formylmethanofuran dehydrogenase 2 subunit C, Tungsten-containing formylmethanofuran dehydrogenase II subunit C.
What is the protein family that this protein belongs to?
Belongs to the FwdC/FmdC family.
Protein: PTH_LAWIP
Sequence: MSIKGIIAGLGNPGGQYEKTRHNIGFMVINKLITITSASKLSGKKFYCELWKTTTIIDNYLLAKPQTYMNLSGEAIHPLVEWYNITKDNLLVIHDELDLPIGKMKLQQGGGTAGHNGLKSIIHNLGTKDFYRLRIGIGRSPLPSENTVNWVLGHLSMKELTTLNNLFPTIFDALSFFIKDEKETAIRMINSFTLSETVNLS
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNTP_PSESM
Sequence: MNPISLLFLALAMSTDAFAAALGKGASLHKPRFIEALRTGLIFGAIETITPVIGWGIGQVAARFAESWDHWIAFTLLLVLGLHMIYNGLKHDHEEEQEKPGSHSFWILAVTAFATSIDALAVGVGLAFVDVNIMVAALAIGLATTVMVTIGVMLGRVLGTMVGKRAEIVGGIVLIVVGTTILYEHLTAAA
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KHSE_RHOPT
Sequence: MAVYTDVAADELADFLSRYDIGDLLSYKGIAEGVENSNFLLHTSRGYFILTLYEKRVARDDLPFFLSLMTHLADSGINCPQPVADREGRTLATLAGRPAAIISFLDGVWPRKPSVVHCAGVGQALAKMHLAGRDFAMKRANALSVAGWRPLFAAAEARADEVQPGLRDFLAAELSYLESGVWPSDLPQGLIHADLFPDNVFFIGDDVSGIIDFTFACNDLLAYDVAICLNAWCFEADHAFNVTKARALLSAYTRERPLDAAEQAALPLLARGAALRFLLTRLVDWLNVPEGALVKPKDPMEYVRKLRFQQNVAGIRDYGVEIAGAVA
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: ATG12_AJECN
Sequence: MASTPPLSASPNSSKPTSPRASNRGLGLTSRQGSRSSRPSNDNGSRGVATTPIPDEDHSADLPLTMSASIVLTGLPKDAHQALADVEAIDSGKVTVRFQPLPSAPILRNRVFKISASQKFETVVKFLRKKLDCKDTDSVFCYVNSVFAPGLDEGVGGLWRCFKTDDQLIVAYSMTPAFG
What is the function of this protein?
Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.  Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function.  The ATG12-ATG5 conjugate functions as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes (By similarity).
What are the official names of this protein?
Ubiquitin-like protein ATG12, Autophagy-related protein 12.
What is the protein family that this protein belongs to?
Belongs to the ATG12 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: FB219_ARATH
Sequence: MDAPNPKRPCLVPLGTSSIENPCSLPIAPDFNQSNIDLTISSFLSLSDLPLFSLPLSIGCSFDRVLDNVIPSIAGTSRDEFDQDRFLDRTLQLASLLYKSTKRCIRKRATLQNSTSWPLLPELTIKVFSMLDTKSLMQASACCTMFNKCAMDRVCYSHIDLTTAAEDVDNGVVCVMIHRAGKELRSLKLGSISSSAEPTTSLLTRSCLTPLTFNHGFTGGHLRSLHLYHLRMIDCGSLSPVLSACLNLTDLKIVGLDNPLEQLGLLTRNCRLIEHLFIEIYGAAGLITDSSLLEFAANCPNLSSISLLGFLLNDAILQKLIKGFRRLKHINLSSSPEISGCFFRGLELCGKDSPLETLILRDCYILKESEVLLFLNSLLAGDFKYIRLIDVSNVDGLVCDGGNRTFEPRFPIEELKKQRSNVTFVAIFESQSSLSSSRFPLEELNKERPGLTFVAEFRSPSPSESDVRSPSPSSSSDSSSSSDSSSSSSSGESSDESGTEEEEDED
What are the official names of this protein?
F-box protein At4g02760.
Protein: RL33_BRUO2
Sequence: MAKATTIKIKLLSTADTGFFYVTKKNSRTMTEKMTKTKYDPIARKHVEFKETKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RS20_PARMW
Sequence: MANNQAAKKRIEIAERNRLRNRTYKSALRTLMKRCFVACEAYSKEPGDAAKATVSASMNAAFSKIDKAVKVGVLHRNNGAHQKSRLSATVRQVLEPSS
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RL11_AERHH
Sequence: MAKKVTAYIKLQVKAGSANPSPPVGPALGQHGVNIMEFCKAFNARTEKLEKGSPTPVVITVYSDRSFTFETKTPPAAFLLKKAAGIQSGSAKPNKDKVGKVTVAQLQEIAKTKEPDMTGADLDAKVRCIAGSARSMGLVVED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: Y1082_METJA
Sequence: MKEFIINRLKKFTIEDLMRCILGLQEIEIRVYFDLLENGEGSVLEIAERVNRDRTTVQKALRSLMNCGLVDRRKVTEKVGYKYIYNAVDLDRVSDIIEELLDDWYQNVKKWLTYFRENRK
What are the official names of this protein?
Uncharacterized protein MJ1082.
What is the protein family that this protein belongs to?
To M.jannaschii MJ1503.
Protein: LEXA_HERA2
Sequence: MSGLSQRQQRIYDYIKQFIRTNGYAPAIRDIQRELSISSTSVVAYNLRALESKGHIRREGNISRAIELINAEQPLPTVLGGQRVPVLGVIAAGQPIPVPNDSANSDDSVLVPEEIVGNDKLGDVYALRVKGYSMVDALIADGDIVLLRYQATAENGEMVAARIRDENEVTLKRIYWEGDRVRLQPANVTMEAMYYPSTNVEVQGRVVGVIRNLG
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: EFTS_RHOP2
Sequence: MATITAAMVKELRETTGVGMMDCKQALAENDGNMEAAVDWLRKKGLSKAAKKAGRVAAEGLIGALTDGTKGVVIEVNSETDFVARNEQFQGLVKMIAQVALKVGADVDKINAAPVGSSTVAGAISDAIATIGENMTLRRAAALEVSQGVVASYVHGAVIEGAGKMGVIVALESTGKTDELAALGRQLAMHVAAANPQALDPAGLDPDVVRREREVMADKYRQQGKPENMIEKIVENGLKTYYKEVCLLEQAYIHDEKGKAVGQAVKEAEGKVGAPIKIIGFVRYALGEGIEKQTSDFAAEVAAVSGQK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA1_FRAT1
Sequence: MSNNNSKLEFVPNIQLKEDLGAFSYKVQLSPVEKGMAHILGNSIRRVLLSSLSGASIIKVNIANVLHEYSTLEDVKEDVVEIVSNLKKVAIKLDTGIDRLDLELSVNKSGVVSAGDFKTTQGVEIINKDQPIATLTNQRAFSLTATVSVGRNVGILSAIPTELERVGDIAVDADFNPIKRVAFEVFDNGDSETLEVFVKTNGTIEPLAAVTKALEYFCEQISVFVSLRVPSNGKTGDVLIDSNIDPILLKPIDDLELTVRSSNCLRAENIKYLGDLVQYSESQLMKIPNLGKKSLNEIKQILIDNNLSLGVQIDNFRELVEGK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha 1, RNAP subunit alpha 1, RNA polymerase subunit alpha 1, Transcriptase subunit alpha 1.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RSMH_CAMJ8
Sequence: MEIPHIPVLLNEVQEIFKNLKTGYFLDCTLGFGGHSEALLKNHPDLKFIACDQDQQALEFSKKRLKDFHNRITFIQSNFSEVLEKISYKEELRGILADIGVSSFQLDNNERGFSVNSDFLDMRMNQNSKISAYEIINTYTKEQLTSIFKDYGELHDAHFIAEKICLERSKNPIKSAKELYQIIGKGKQNHRKISKATLAFQAIRIEVNQELKVLKDFLGHLENLKPKNCILAIISFHSLEDRIVKNFFKKWSKNCICDEKIMRCECGNNHSLGQIITKKAISASKEELLKNSRSSCAKMRAFYFNNLDNK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMSA_ARATH
Sequence: MVRVKQKNLESYRSNGTYPPTWRNPTTSFAPDQHRVSIHSSLKSKTKRRRLYKEADDNTKLRSSSSTTTTTTTMLLRISGNNLRPLRPQFLALRSSWLSTSPEQSTQPQMPPRVPNLIGGSFVESQSSSFIDVINPATQEVVSKVPLTTNEEFKAAVSAAKQAFPLWRNTPITTRQRVMLKFQELIRKNMDKLAMNITTEQGKTLKDSHGDIFRGLEVVEHACGMATLQMGEYLPNVSNGVDTYSIREPLGVCAGICPFNFPAMIPLWMFPVAVTCGNTFILKPSEKDPGASVILAELAMEAGLPDGVLNIVHGTNDTVNAICDDEDIRAVSFVGSNTAGMHIYARAAAKGKRIQSNMGAKNHGLVLPDANIDATLNALLAAGFGAAGQRCMALSTVVFVGDAKSWEDKLVERAKALKVTCGSEPDADLGPVISKQAKERICRLIQSGVDDGAKLLLDGRDIVVPGYEKGNFIGPTILSGVTPDMECYKEEIFGPVLVCMQANSFDEAISIINKNKYGNGAAIFTSSGAAARKFQMDIEAGQIGINVPIPVPLPFFSFTGNKASFAGDLNFYGKAGVDFFTQIKTVTQQWKDIPTSVSLAMPTSQKQ
What are the official names of this protein?
Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial, MM-ALDH, MMSDH, Malonate-semialdehyde dehydrogenase [acylating], Aldehyde dehydrogenase family 6 member B2.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS19_STAS1
Sequence: MARSIKKGPFADDHLKKKVEAQSGSEKKQVIKTWSRRSTIFPDFIGHTFAVYDGRKHVPVFVTEDMVGHKLGEFAPTRTFKGHAADDKKTRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: KHSE_ARATH
Sequence: MASLCFQSPSKPISYFQPKSNPSPPLFAKVSVFRCRASVQTLVAVEPEPVFVSVKTFAPATVANLGPGFDFLGCAVDGLGDHVTLRVDPSVRAGEVSISEITGTTTKLSTNPLRNCAGIAAIATMKMLGIRSVGLSLDLHKGLPLGSGLGSSAASAAAAAVAVNEIFGRKLGSDQLVLAGLESEAKVSGYHADNIAPAIMGGFVLIRNYEPLDLKPLRFPSDKDLFFVLVSPDFEAPTKKMRAALPTEIPMVHHVWNSSQAAALVAAVLEGDAVMLGKALSSDKIVEPTRAPLIPGMEAVKKAALEAGAFGCTISGAGPTAVAVIDSEEKGQVIGEKMVEAFWKVGHLKSVASVKKLDNVGARLVNSVSR
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate (PubMed:15703056).  Is specific for L-homoserine and cannot use other substrates such D-serine, L-serine, D-threonine and L-threonine, galactose or D-homoserine in vitro.  Required for susceptibility to the downy mildew pathogen Hyaloperonospora parasitica.
What are the official names of this protein?
Homoserine kinase, Protein DOWNY MILDEW RESISTANT 1.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: RR15_TRACE
Sequence: MVKNSFISIISQEENKENRGSVEFQIVSFTNKIDRLTSHLQLHKKDYLSERGLLKILGKRHRLLAYLSKKTRVDYKEFKELIDQLDKTKTRVDYKEFKELIDQLEKKTR
What are the official names of this protein?
30S ribosomal protein S15, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.