PharMolix/UniProtQA huggingface dataset:
Protein: PRD16_HUMAN
Sequence: MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDFTPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAAAKETDFGWEQILTDVEVSPQEGCITKISEDLGSEKFCVDANQAGAGSWLKYIRVACSCDDQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELFQSKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQHMVIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQHVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLNHASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTSLLKSPLNHTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMSDGSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAPNSVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSLPYHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKPKDVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGLPQVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMSAIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQQTNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNFIANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQDDTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLRRAAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAYAMMLSLSEDTPLHTPSQGSLDAWLKVTGATSESGAFHPINHL
What is the function of this protein?
Binds DNA and functions as a transcriptional regulator (PubMed:12816872).  Functions as a repressor of TGF-beta signaling (PubMed:14656887).  May regulate granulocyte differentiation (PubMed:12816872).
What are the official names of this protein?
Histone-lysine N-methyltransferase PRDM16, PR domain zinc finger protein 16, PR domain-containing protein 16, Transcription factor MEL1, MDS1/EVI1-like gene 1.
What is the protein family that this protein belongs to?
Belongs to the PRDM16 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: CLC4A_MOUSE
Sequence: MASEITYAEVKFKNESNSLHTYSESPAAPREKPIRDLRKPGSPSLLLTSLMLLLLLLAITFLVAFIIYFQKYSQLLEEKKAAKNIMHNELNCTKSVSPMEDKVWSCCPKDWRLFGSHCYLVPTVSSSASWNKSEENCSRMGAHLVVIQSQEEQDFITGILDTHAAYFIGLWDTGHRQWQWVDQTPYEESITFWHNGEPSSGNEKCATIIYRWKTGWGWNDISCSLKQKSVCQMKKINL
What is the function of this protein?
C-type lectin receptor that binds carbohydrates mannose and fucose but also weakly interacts with N-acetylglucosamine (GlcNAc) in a Ca(2+)-dependent manner.  Involved in regulating immune reactivity.  Once triggered by antigen, it is internalized by clathrin-dependent endocytosis and delivers its antigenic cargo into the antigen presentation pathway resulting in cross-priming of CD8(+) T cells.  This cross-presentation and cross-priming are enhanced by TLR7 and TLR8 agonists with increased expansion of the CD8(+) T cells, high production of IFNG and TNF with reduced levels of IL4, IL5 and IL13.  In plasmacytoid dendritic cells, inhibits TLR9-mediated IFNA and TNF production (By similarity).  May be involved via its ITIM motif (immunoreceptor tyrosine-based inhibitory motifs) in the inhibition of B-cell-receptor-mediated calcium mobilization and protein tyrosine phosphorylation (PubMed:11841542).
What are the official names of this protein?
C-type lectin domain family 4 member A, C-type lectin superfamily member 6, Dendritic cell immunoreceptor.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein; Extracellular side.
Protein: OFOB2_AERPE
Sequence: MARSWLDYKTQAWVQWCPGCGDFGILNSIYRAVSELGIDPENLAVVGGIGCSGRTTYYVKGSNFHALHGRAIPVATGVKLANPHLNVIVAGGDGDLMGIGGGHFVALGRRNLNITVLLFDNAVYGLTKGQAAPTLPAWVKTKALSMPNIHDNINPVLLAFAAGYTFIARGYAYHTQQLKELIKTAVRHRGAALVDILQPCPTYNNIMTNKWYEERIYYVDQEEGYDPIIRTPEEFQKKAPAIAAKLMEFGDRIPLGILYWNQTRESFEERLEKIMPGYMSAPPATRRIELEGKPFLHPFDIFKDRLVTP
What is the function of this protein?
Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as pyruvate, 2-oxobutyrate, glyoxylate and 2-oxoglutarate to form their CoA derivatives.
What are the official names of this protein?
2-oxoacid:ferredoxin oxidoreductase 2, subunit beta, OFOR2.
Protein: AQP_ENTBH
Sequence: MNTSTKLICQKLFAEMLCSCIFGFAVYSAILNTKASNSSISSTTVGLTVCFSSISLIYTFCDHSVAHFNPAITIAAICTGKLDILLGIGYVIAQLIGFILATLLTVVCFPYGYLKTMEFIASARISDDISTVNLFFTEFILSFILVFIAFEVGINAIREPGVTLFVGIKQIDRSKFAPLTIGITLGFLAFLASTTSGGAFNPGIVWGPAIMGGNFDDFVIYIISELSGGLLGAFIQVFLLFK
What is the function of this protein?
Water channel required to facilitate the transport of water across membranes.  Involved in osmotolerance (By similarity).
What are the official names of this protein?
Aquaporin.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MDR1_RAT
Sequence: MEFEEGLNGRADKNFSKMGKKSKKEKEKKPAVGIFGMFRYADWLDKLCMALGTLAAIIHGTLLPLLMLVFGYMTDSFTPSRDPHSDRAITNQSEINSTHTVSDTSLEEDMAMYAYYYTGIGAGVLIVAYIQVSLWCLAAGRQIHKIRQKFFHAIMNQEIGWFDVNDAGELNTRLTDDVSKINDGIGDKLGMFFQSITTFSAGFIIGFISGWKLTLVILAVSPLIGLSSAMWAKVLTSFTNKELQAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKNLEEAKRVGIKKAITANISIGIAYLLVYASYALAFWYGTSLVLSNEYSIGQVLTVFFSILLGTFSIGHLAPNIEAFANARGAAYEIFKIIDNEPSIDSFSTKGHKPDSIMGNLEFKNVYFNYPSRSEVKILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQRLYDPIEGEVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHEELMKEKGIYFKLVMTQTRGNEIEPGNNAYESQSDTGASELTSEESKSPLIRRSIRRSIHRRQDQERRLSSKEDVDEDVPMVSFWQILKLNISEWPYLVVGVLCAVINGCIQPVFAIVFSKIVGVFSRDDDHETKQRNCNLFSLLFLVMGMISFVTYFFQGFTFGKAGEILTKRLRYMVFKSMLRQDISWFDDHKNTTGSLTTRLASDASNVKGAMGSRLAVVTQNVANLGTGIILSLVLVYGWQLTLLLVVIIPLIVLGGIIEMKLLSGQALKDKKELEISGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNALKKAHVFGITFAFTQAMIYFSYAACFRFGAYLVARELMTFENVMLVFSAVVFGAMAAGNTSSFAPDYAKAKVSASHIIGIIEKIPEIDSYSTEGLKPNWLEGNVKFNGVKFNYPTRPNIPVLQGLSFEVKKGQTLRLVGSSGCGKSTVVQLLERFYNPMAGTVFLDGKEIKQLNVQCVRALGIVSQEPILFDCSIAENIAYGDNSRVVSHEEIVRAAREANIHQFIDSLPEKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCVVIAHRLSTIQNADLIVVIQNGQVKEHGTHQQLLAQKGIYFSMVQAGAKRS
What is the function of this protein?
Translocates phospholipids and drugs across the membrane.  Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane.  Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins.  Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
What are the official names of this protein?
ATP-dependent translocase ABCB1, ATP-binding cassette sub-family B member 1, Multidrug resistance protein 1, P-glycoprotein 1, Phospholipid transporter ABCB1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Apical cell membrane.
Protein: IF4B3_ARATH
Sequence: MAAAVSSVWAKPGAWALEAEEHEAELKQQPSPTNQKSSAEDSSDFPSLAAAATTKTKKKKGQTISLAEFATYGTAKAKPAPQTERLTQAELVALPTGPRERSAEELDRSKLGGGFRSYGGGRYGDESSSSRWGSSRVSEDGERRGGGFNRDREPSRDSGPSRADEDDNWAAAKKPISGNGFERRERGSGGGFFESQSQSKADEVDSWVSTKPSEPRRFVSSNGGGGDRFEKRGSFESLSRNRDSQYGGGGGSESDTWGRRREESGAANGSPPPSGGSRPRLVLQPRTLPVAVVEVVKPESPVLVIVEKPKGANPFGNARPREEVLAEKGQDWKEIDEKLEAEKLKDIAAAMEKPNEKSTGKMGFGLGNGRKDEERIERSWRKSTEHSEEDAQEEEPAVEGAKKEETEDKPAVEEAKKEETEGEQAVEEAKKEETGGEPAVEEAKKEETEDKI
What is the function of this protein?
Promotes the eIF4F and eIF4A RNA-dependent ATP-hydrolysis activity with different efficiency depending on mRNAs, thus providing mRNA discrimination during initiation of translation.
What are the official names of this protein?
Eukaryotic translation initiation factor 4B3, AtTif4B3, eIF4B3.
What is the protein family that this protein belongs to?
Belongs to the eIF-4 subunit B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CASP3_RICCO
Sequence: MDSEKTGEAKITIQEPKAADPKGKGIADAPPPPVVVTTAKAIQKLPRGGWKKGVAIFDFVVRLCAIATGLAATGIMGTTEQTLPFFTQFFQFHAEYNDLPTFMFFVFANGIASGYLILSLPFSIVCIVRPLAIVPRLLLIIFDTVVMALTIAAASAAAAIVYLAHNGNSNANWNAICQQFNDFCQQTSTAVVASFITAAMLTFLIVLSAFALKRN
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 3, RcCASP3.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: PPR1B_HUMAN
Sequence: MDPKDRKKIQFSVPAPPSQLDPRQVEMIRRRRPTPAMLFRLSEHSSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQGLEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPSPSEPGT
What is the function of this protein?
Inhibitor of protein-phosphatase 1.
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 1B, DARPP-32, Dopamine- and cAMP-regulated neuronal phosphoprotein.
What is the protein family that this protein belongs to?
Belongs to the protein phosphatase inhibitor 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLX1_NEUCR
Sequence: MSTTTTQIQPKPIPALYTVYILRSQPRHASLYIGSTPHPPRRLSQHNGLAKGGAYRTSKISLRPWNMVCLVSGFPSMIAALKFEWALNNPHKSLHIPAEKRAEAVKGLGRRKTGHLKRPRKSLVGVMEALRMLVGVRSFGRWPLRVHFFEEDVWRVWERGGWKAKSGGGGVGELGDLKVEVVTDFGSPTAPQGAGVIGMGEEAENDPHDDDDGDDAQDENKHGIYALPLDYAPIKDYVAKSQEIWEFERQGSCVVCKEAMVAGRGLYAICPNTSCEAVGHLDCWSRCLLKQETRRMKIDEGDEILPVKGECPKCHGEVLWGDMMKELTLRIRGQAEVEKLLKKKKRRRAAKGKEKGKGKVADEKGNNAEGRNTKGNREVKTTPQRVVEDSEDSEFLDIACLQ
What is the function of this protein?
Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit slx1.
What is the protein family that this protein belongs to?
Belongs to the SLX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1059_STAAT
Sequence: MNLIPRTSIVVYLKHMKHERQIRKYGHIVHSNRDRKFVIMYVNEQDVDQIVHKLMQLKYVRHIDGSPYKYLKKTYEKEKHEIYN
What are the official names of this protein?
UPF0298 protein USA300HOU_1059.
What is the protein family that this protein belongs to?
Belongs to the UPF0298 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARA_METS5
Sequence: MTYCKRGTEGLIYLEDGTLLRGCGFGAKGVRYGEVVFTTAMNGYPESMTDPSYRGQILIITHPLVGNYGVPNPIVRNGILQNFESEQIQIEGLVVTEETDPSKWNSSKSLHQWMAEQGIPGVSSVDTRLLVKKVRTLGSMMGVIASGEHVEDPRKYIEMRYDEIDFTKFTSPKSPIIHQNNSPDIIVLVDCGIKHGILEELYKTGFTIVRVPCKSSADEIMNYSPKGIVFGNGPGNPNILKDLVKNFSAVMEYKLPTLGICLGHQVATLALGGNVRKMKFGHRAINKPVTDISNNKCYISTHNHGYGVYKEDIPPDTQIWFVNPDDGVVEGLIHKRLPLITTQFHPEARPGPNDTTWVFQKFKKMVIKDEGN
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: CO061_HUMAN
Sequence: MEALRRAHEVALRLLLCRPWASRAAARPKPSASEVLTRHLLQRRLPHWTSFCVPYSAVRNDQFGLSHFNWPVQGANYHVLRTGCFPFIKYHCSKAPWQDLARQNRFFTALKVVNLGIPTLLYGLGSWLFARVTETVHTSYGPITVYFLNKEDEGAMY
What are the official names of this protein?
Uncharacterized protein C15orf61.
What are the subcellular locations of this protein?
Secreted.
Protein: RS16_RHOCS
Sequence: MSVKIRLSRGGAKKRPFYSIVVANSRAPRDGDFIEKVGTYNPMVPHDHPERVVLQEDRIKEWLAKGAQPTDRVARFLGKANLIPMPALRETPKKSAPKAKAQERAKAAG
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: Y1708_CORGB
Sequence: MAGHSKWATTKHKKAANDAKRGKEFAKLIKNIEVAARTGGGDPSANPTLDDMIKKAKKASVPNDNIERARKRGSGEEAGGADWMNIMYEGYGPNGVAMLIECLTDNRNRAATEVRTAMTKNGGNLGESGSVSYMFTRTGVVTVQKGELSEDDVLMAVLEAGAEEVNDNGDLFEITCAPTDIQAVRDALVEAGIEVEDSESDFRASVEVPLDADGARKIFKLVDALEDSDDVQNVYTNIDLSDEVLAELESD
What are the official names of this protein?
Probable transcriptional regulatory protein cgR_1708.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSPLR_ORYSJ
Sequence: MRELAGSPGTWSGLSLRVGQLVFAAASVCATASALGFAAYTAFCYLIASMGLQALWSLGLACLDCYALKFKKDLHSAVLLSLFVVGDWVTAILSFAASCSAAGVVVLFDRDIYACRNPQLPCGRFELAIACAFLSWAFSATSALVMFWLLASL
What are the official names of this protein?
CASP-like protein 5B1, OsCASPL5B1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DSBC_BORPA
Sequence: MSGPPFSGAGMNFRITVWCAAAAVWSSGALAQDGAGQAAPGTPDKVYSTTGTAPAKPGDKVYSTRSAQAPDPQADAVKERFAQRFEGFDVTAVRRTPYGLFEVQIGTDLLYTDEKVTWVMEGPLIDALTRRDVTRERQEKLSSVPFDELPLDLAVKQVKGDGSRVMAVFEDPNCGYCKQLHRTLEDMDNITVYTFLYPILSPDSTTKVRDIWCASDPAKVWKDWMVRGQRPPTAECDAPVEQWLALGRQLMVRGTPAIFFKSGGRVSGALPRDELEARL
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by transferring its disulfide bond to other proteins and is reduced in the process (By similarity).
What are the official names of this protein?
Probable thiol:disulfide interchange protein DsbC.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbC subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y1627_ARCFU
Sequence: MRTRIKEFRAKFNMTQEELAKRVGVRRETIVFLEKGKYNPSLKLAYKIARVFNAKIEDIFIFDEEELWEKR
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator AF_1627.
Protein: GLMM_ALKEH
Sequence: MKKEYFGTDGIRGTVGEPPITPDFMLHLGWAAGRVLARAGQSSVLVGKDTRISGYMLESALESGFAAAGVNVKLLGPMPTPAIAYLTRTLRAAAGVVISASHNPHEDNGIKFFSDDGEKLDDATELAIEAELRQPLKPAPSARLGKASRINDAPGRYIEFCKRSFPYELSLRGLRLVVDCANGATYHVAPAVFHELGAEVIPLADDPDGLNINADCGSLHPKGLQAAVREHDADAGIAFDGDGDRVIMVDHRGEVVDGDGLLYIIARQRMANGGLAGPVVGTVMSNLGLEQGIGRLGLPFLRAKVGDRYVMEMLRREGGILGGESSGHLICLDRTTTGDGIVSALQVLEAMAAQERTLAELADGMDRLPQIMVNVPISRGVPVQDHATVTDAVRDAETRLAGRGRVLLRPSGTEPVLRVMVEGPDQAEVSATAEAIAGAVREAHATLTAPR
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: VPH2_YEAST
Sequence: MFEIKLNDRITEFLRKFKNSAKSNEGIDEDIDLFLKRHAIPMQSLLFYVKEYRKDSDLQCSIKELLKPLEFEFKPKAVRGLHYSEDFKKKLEFLKYQEQELEYQSMVKRSKSVFSLQEDDELTPSQINKQIKEQVTTVFNVLVSVISVVVAIWYWTGSSTNFPVHVRLLLCLFFGILVLVADVVVYNSYLKKLEEAKVKEKTKVEKKKVLSKITL
What is the function of this protein?
Required for vacuolar ATPase assembly.
What are the official names of this protein?
Vacuolar ATPase assembly integral membrane protein VPH2, Protein VMA12.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CYB_HETSI
Sequence: MSNQHTLLMFNLLPVGLNISTWWNFGSMLLTCTALQTTTGFFLAIHYTANINLAFTSIVHITRDVPYGWIMQNIHATGASMFFICIYIHIARGLYYGSYLNKEVWVSGTTLLVTLMATAFFGYVLPWGQMSFWAATVITNLLTAVPYLGSTLTTWLWGGFSINDPTLTRFFALHFILPFIIISTSLIHVMLLHNEGSSNPLGTNSDIDKIPFHPYHTYKDTLMLTTLLTLLFITTSFFPNIFNDPENFSKANPLITPQHIKPEWYFLFAYGILRSIPNKLGGTMALVMSIIILLTAPFTHTSHVRSMTFRPMAQVLFWTFIATFMLITWAATKPVEPPFTTIGLSTSILYFSFFIINPLLGWSENKIMNTHN
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RUVC_AGRRK
Sequence: MQNTIRIIGIDPGLRRTGWGVIDTLGNSLRFVASGTVTSDGDMDLASRLCQLHDGLADIVHGYKPDEAAVEQTFVNKDAVATLKLGQARGIAMLVPARAGLPVAEYAPNAVKKAVIGVGHGEKQQIHMMLKILMPKAEFKGNDAADALAIAICHAHNRGANRLRQAALAG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: RL9_SHIDS
Sequence: MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNIEFFEARRAELEAKLAEVLAAANARAEKIDALETVTIASKAGDEGKLFGSIGTRDIADAVTAAGVEVAKSEVRLPNGVLRTTGEHEVSFQVHSEVFAKVIVNVVAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: PURNU_STAES
Sequence: MKERFIKKTHYLDYQFDEPTDIKLGFTTRENGLSPYPNHSFNMARYISDSAHHITHHQDILANLIGYPRDEWVFPIQTHDSRIVEVTSEHKGTNIDELTDDLHGIDGMYTFDSHILLTMCYADCVPVYFYSEPHGYIGLAHAGWRGTYGQIVKEMLKKVDFDYEDLKIVIGPATSNSYEINDDIKNKFEELTIDSTLYIETRGKNQHGIDLKKANALLLEEAGVPSKNIYVTEYATSENLDLFFSYRVEKGQTGRMLAFIGRK
What is the function of this protein?
Purine nucleoside enzyme that catalyzes the phosphorolysis of adenosine and inosine nucleosides, yielding D-ribose 1-phosphate and the respective free bases, adenine and hypoxanthine.  Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate.  Also has adenosine deaminase activity.
What are the official names of this protein?
Purine nucleoside phosphorylase SE_0862, Adenosine deaminase SE_0862, S-methyl-5'-thioadenosine phosphorylase SE_0862.
What is the protein family that this protein belongs to?
Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.
Protein: NORM_CAUVC
Sequence: MTVVTTMPRDAAGTALLPERPRGPIMTDLIELLRLAGPVVLSRLGIMVMGLTDAIVVGHFSAQQLGYHAMAWAPSSVFVTATVGLLVGVQVMTARAMGAGNPHETGAVLRRGLVYAGWLGFGSMALLALFGPMFLQAMGLKDGLAEGATLPLIVFSLSLPVYAISVVLTFWLEGLSRPGPGAAMMWLANVVNLGANLLLVPGVLGPPALGAVGGAWATFIARTALALALAIFVIRMKEARELGVFDKPARDRPAEIEQRRIGYGAGASNFFEVSAFAGMNLICGWISAVAVAAYTVVLNVSAIIFMVPLGVASATAVMVGRAYGARDPAGMTRAGWIAFAVIGVIGVLFGLLLYPTKHWVALAYTTDPAALALILPALVLACLFFAPDAVQVVAAQALRARGEVWVPTITHLISYALVMGPLAWWLAIPKGMGLNGVLVSIIVTSFLAAGFLLMRFRMLDWRDRKAAQEAA
What is the function of this protein?
Multidrug efflux pump.
What are the official names of this protein?
Probable multidrug resistance protein NorM, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: END4_ENTFA
Sequence: MLLGSHVSMSGKKMLLGSAEEAASYGSTTFMIYTGAPQNTRRKPIEEMNIEAGQAFMKEHNLSNIVVHAPYIINLGNTIKTENFGFAVDFLRQEIERAQALGATQITLHPGAHVGAGPEAGIKQIVKGLNEVLWKEQIPQIALETMAGKGTEIGRTFDELAAIIDGVTLNDKLSVTLDTCHINDAGYNVKDDFDGVLVEFDKIIGLDRLKVIHVNDSKNPMGSHKDRHANIGFGTIGFEALNGVVHHEKLTALPKILETPYVGEDKKNKKAPYGFEIAMLKNQTFDPELLEKIQGQN
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: TRPD_BACAH
Sequence: MNNYLRKLVEGQHLTEEEMYKAGLLLLNENILESEIAAFLVLLKAKGETAEEIYGLVRALREKALPFSNHIQGAMDNCGTGGDGAQTFNISTTSAFVLAGAGVKVAKHGNRAVSSKTGSADLLEELGVNISSTPNEIDYLLEHVGIAFLFAPAMHPALKRIMKIRKELNVPTIFNLIGPLTNPVNLETQFVGIYKRDMLLPVAQVLQKLGRKQALVVNGSGFLDEASLQGENHVVILKDNEIVETSIEPEKYGFSIVKNEEIRGGNSKENAKITLGVLSGEKSVYRDTVLFNAGLALFANGKAKTIEEGITLAAHSIDSGKALAKLNLLIAASNEKLERVN
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: YXNA_BACSU
Sequence: MTIDHSVTNTEQLEQQNPAIKTKLKLKKLKDQVIVITGASSGIGLVTARMAAEKGAKVVAAARNEEALKELTDELKEKGHDAIWVKADVGKEEDVNRIAETAISTFGRFDTWVNNAAVSTFGHAMDVTVEDMKRMFDTNFWGPVYGTRAAVKHYTGRGVPGALINVGSLFGDRGTVIQSTYASAKFALHGWTESIRMELEKEQAPVSVTLIHPGRIDTPYNEHAHSYLDKQPAHYRSMIYPPEAVAEAILFAAEHPKRDMYIGSQAKAIAMLGALFPRLTDRLMEKIMYHSQHAERPSNPREESALYDAGCGMHDRGTNKGWMRSRSYYTKATKRPIVSAAVVAGLVAWAAAKRCR
What are the official names of this protein?
Uncharacterized oxidoreductase YxnA.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: COAE_STAAW
Sequence: MPKVIGLTGGIASGKSTVSELLSVFGFKVVDADKAAREAVKKGSKGLAQVREVFGDEAIDENGEMNRRYMGDLVFNHPEKRLELNAIIHPIVRDIMEEEKQEYLKQGYNVIMDIPLLFENELENTVDEVWVVYTSESIQMDRLMQRNNLSLEDAKARVYSQISIDKKSRMADHVIDNLGDKLELKQNLERLLEEEGYIEKPNYGEED
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRIH_TRENE
Sequence: MESQVRQNFHKDCEAAINRQINLELYASYSYLSMAYYFDRDDVALPGFAHFFKHQSEEEREHAEKLMKQQNQRGGRIFLQDVKKPDRDEWGSGLDALECALQLEKNVNQSLLDLHKVCSEHNDPHMCDFLETHYLDEQVKSIKELGDWVTNLRRLGAPQNGMAEYLFDKHTLGK
What is the function of this protein?
Stores iron in a soluble, non-toxic, readily available form.  Important for iron homeostasis.  Has ferroxidase activity.  Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.  Also plays a role in delivery of iron to cells.  Mediates iron uptake in capsule cells of the developing kidney (By similarity).
What are the official names of this protein?
Ferritin, heavy subunit, Ferritin H.
What is the protein family that this protein belongs to?
Belongs to the ferritin family.