PharMolix/UniProtQA huggingface dataset:
Protein: SYDND_BRUA2
Sequence: MHRYRSHTCAALRKTDVGSNVRLSGWVHRVRDHGGILFIDLRDHYGITQIVADPDSPAFKVAETVRGEWVIRVDGEVKARADDAVNTNLPTGEVEIFATEIEVLSPAKELPLPVFGEPDYPEDIRLKYRFLDLRRETLHKNIMSRTKIIAAMRRRMTEIGFNEFSTPILTASSPEGARDFLVPSRIHPGKFYALPQAPQQYKQLLMVAGFDRYFQIAPCFRDEDPRADRLPGEFYQLDLEMSFVTQEEVWETMEPVMRGIFEEFAEGKPVTKVFRRIAYDDAIRTYGSDKPDLRNPIEMQAVTDHFAGSGFKVFANMIANDAKVEVWAIPAKTGGSRAFCDRMNSWAQSEGQPGLGYIFWRKEGDKLEGAGPIAKNIGEERTEAIRKQMGLEDGDACFFVAGLPSKFYKFAGDARTRAGEELNLVDRDRFELAWIIDFPFYEWDEDNKKIDFAHNPFSLPQGGMDALENMDPLEIKAYQYDLVCNGFEIASGSIRNQLPEVMVKAFEKVGLSQQDVEERFGGLYRAFQYGAPPHGGMAAGIDRVIMLLVGAKNLREISLFPMNQQALDLLMGAPSEVSPAQLRDLHVRLAPVQKS
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_ECO7I
Sequence: MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYLYDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAQLVTELVPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTLGQPNSPGVPADFAKHTLTCTYNDLASVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPEFLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVVPDLTCLGKIIGGGMPVGAFGGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGVHETLDELTTRLAEGLREAAEEAGIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHMMLDEGVYLAPSAFEAGFMSVAHSMEDINNTIDAARRVFAKL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YTSF_SPICI
Sequence: MENTEKGTIIAISMAAFLFVVVSLSIIGYLISFTKREFKPRFINKKILIILFTVLGINLPIVILGFLFQFVINLSSTAPLIIMIVLAFGLTVGVGIYIFLFLQLIAVGIDEKEIAFLGERILIRKITRVERNDKTNQLVIYYIEGSRSKKKCRFSLASQAGQFMFNNVNLLNQEIMPFVDGQAEPELKVSEQENSEAPVSEPKEDEKTKKD
What are the official names of this protein?
Uncharacterized 23.8 kDa protein in tsf 3'region, Protein X.
Protein: LIUE_PSEAE
Sequence: MNLPKKVRLVEVGPRDGLQNEKQPIEVADKIRLVDDLSAAGLDYIEVGSFVSPKWVPQMAGSAEVFAGIRQRPGVTYAALAPNLKGFEAALESGVKEVAVFAAASEAFSQRNINCSIKDSLERFVPVLEAARQHQVRVRGYISCVLGCPYDGDVDPRQVAWVARELQQMGCYEVSLGDTIGVGTAGATRRLIEAVASEVPRERLAGHFHDTYGQALANIYASLLEGIAVFDSSVAGLGGCPYAKGATGNVASEDVLYLLNGLEIHTGVDMHALVDAGQRICAVLGKSNGSRAAKALLAKA
What is the function of this protein?
Involved in the L-leucine, isovalerate and acyclic monoterpene catabolism.  Catalyzes the cleavage of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to yield acetyl-CoA and acetoacetate.  It can also catalyze the cleavage of 3-hydroxy-3-isohexenylglutaryl-CoA (HIHG_CoA) to yield 7-methyl-3-oxooct-6-enoyl-CoA and acetate.
What are the official names of this protein?
3-hydroxy-3-isohexenylglutaryl-CoA/hydroxy-methylglutaryl-CoA lyase, HIHG-CoA lyase, HMG-CoA lyase, (S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase, 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA acetate-lyase.
What is the protein family that this protein belongs to?
Belongs to the HMG-CoA lyase family.
Protein: FYN_HUMAN
Sequence: MGCVQCKDKEATKLTEERDGSLNQSSGYRYGTDPTPQHYPSFGVTSIPNYNNFHAAGGQGLTVFGGVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATEPQYQPGENL
What is the function of this protein?
Non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated signaling, cytoskeletal remodeling, cell motility, immune response and axon guidance.  Inactive FYN is phosphorylated on its C-terminal tail within the catalytic domain.  Following activation by PKA, the protein subsequently associates with PTK2/FAK1, allowing PTK2/FAK1 phosphorylation, activation and targeting to focal adhesions.  Involved in the regulation of cell adhesion and motility through phosphorylation of CTNNB1 (beta-catenin) and CTNND1 (delta-catenin).  Regulates cytoskeletal remodeling by phosphorylating several proteins including the actin regulator WAS and the microtubule-associated proteins MAP2 and MAPT.  Promotes cell survival by phosphorylating AGAP2/PIKE-A and preventing its apoptotic cleavage.  Participates in signal transduction pathways that regulate the integrity of the glomerular slit diaphragm (an essential part of the glomerular filter of the kidney) by phosphorylating several slit diaphragm components including NPHS1, KIRREL1 and TRPC6.  Plays a role in neural processes by phosphorylating DPYSL2, a multifunctional adapter protein within the central nervous system, ARHGAP32, a regulator for Rho family GTPases implicated in various neural functions, and SNCA, a small pre-synaptic protein.  Participates in the downstream signaling pathways that lead to T-cell differentiation and proliferation following T-cell receptor (TCR) stimulation.  Phosphorylates PTK2B/PYK2 in response to T-cell receptor activation.  Also participates in negative feedback regulation of TCR signaling through phosphorylation of PAG1, thereby promoting interaction between PAG1 and CSK and recruitment of CSK to lipid rafts.  CSK maintains LCK and FYN in an inactive form.  Promotes CD28-induced phosphorylation of VAV1.  In mast cells, phosphorylates CLNK after activation of immunoglobulin epsilon receptor signaling (By similarity).
What are the official names of this protein?
Tyrosine-protein kinase Fyn, Proto-oncogene Syn, Proto-oncogene c-Fyn, Src-like kinase, SLK, p59-Fyn.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane. Note=Present and active in lipid rafts. Palmitoylation is crucial for proper trafficking.
Protein: 3MGH_RHIEC
Sequence: MTDGGMTKDAIGAGALAGEGLRAFFERDAITVARDLLGCHLTVDGAGGRITETEAYFPDDEASHSFRGPTKRNGAMFGRPGNVYIYRIYGMYWCLNFVCHPGSAVLIRALEPETGIAAMMERRGTDMLTALCSGPGKLCQALGIDIEINDRLLDLPPYALTPSTPVPIVAGKRIGITRNAEAPWRFGIQGSRYLSKPFR
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: LUXS_STRP8
Sequence: MTKEVIVESFELDHTIVKAPYVRLISEEFGPKGDRITNFDVRLVQPNQNSIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKVIKSSLEEIATGITWEDVPGTTLESCGNYKDHSLFAAKEWAQLIIDQGISDDPFSRHVI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD) (By similarity).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: RLMH_SHEB8
Sequence: MKLQLIAVGTRMPDWVTRGFEEYQRRFPRDMALELIEIPAGKRGKNADIVRILQKEGEQMLAAIPKGNHIVSLDLPGKNWTTPELATALTKWQLDGRDVSLLIGGPEGLAPACKEAANQSWCLSALTLPHPLVRVVVAESLYRAWSVNTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUD_SHIB3
Sequence: MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAHEVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGALRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQHRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: HEM2_PONAB
Sequence: MQPQSVLHSGYFHPLLRAWQTATTTLNASNLIYPIFVTDVPDDIQPIASLPGVARYGVNRLEEMLRPLVEEGLRCVLIFGVPSRVPKDERGSAADSEESPAIEAIHLLRKTFPNLLVACDVCLCPYTSHGHCGLLSENGAFQAEESRQRLAEVALAYAKAGCQVVAPSDMMDGRVEAIKETLMAHGLGSRVSVMSYSAKFASCFYGPFRDAAKSSPAFGDRRCYQLPPGARGLALRAVDRDVREGADMLMVKPGMPYLDIVREVKDKHPDLPLAVYHVSGEFAMLWHGAQAGAFDLKAAVLEAMTAFRRAGADIIITHYTPQLLQWLKEE
What is the function of this protein?
Catalyzes an early step in the biosynthesis of tetrapyrroles.  Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).
What are the official names of this protein?
Delta-aminolevulinic acid dehydratase, ALADH, Porphobilinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the ALAD family.
Protein: LEPA_HELPY
Sequence: MKTKAPMKNIRNFSIIAHIDHGKSTLADCLISECNAISNREMKSQVMDTMDIEKERGITIKAQSVRLNYTFKGEDYVLNLIDTPGHVDFSYEVSRSLCSCEGALLVVDATQGVEAQTIANTYIALDNHLEILPVINKIDLPNANVLEVKQDIEDTIGIDCSNTNEVSAKARLGIKDLLEKIITTIPAPSGDFNAPLKALIYDSWFDNYLGALALVRIMDGSINTEQEILVMGTGKKHGVLGLYYPNPLKKIPTKSLECGEIGIVSLGLKSVTDIAVGDTLTDAKNPTSKPIEGFMPAKPFVFAGLYPIETDRFEDLREALLKLQLNDCALNFEPESSVALGFGFRVGFLGLLHMEVIKERLEREFGLNLIATAPTVVYEVHLTDNSIKYVQNPSELPPENCIACIKEPFVRATIITPSEFLGNLMQLLNNKRGIQEKMEYLNQSRVMLTYSLPSNEIVMDFYDKLKSCTKGYASFDYEPIENREANLVKLDVRVAGDVVDALSIIIDKNKAYEKGRALVETMKELIPRQLFEVAIQASVGNKIIARETIKSVGKNVTAKCYGGDITRKRKLLEKQKEGKKRMKAIGKVELPQEAFLAILKID
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CSPL2_SORBI
Sequence: MGSIGNGRSDSVVGIQMPPAGSKMVLEPEALQVTTSPVPRWPRLGVVMVATRAVAMVMALLSMSLMVSSKQRGILTIFGIEIPLDANWSFSYSLQFLVAMSTASAAYSLAQLLLIAHKAVKKSPIVPSRRHAWLLFAGDQVFSLAMMSAGSAAAAVANLNRTGIRHTALPNFCKPLPRFCDLSAVSIACAFLSCVFLAASAVIDVIWLSSP
What are the official names of this protein?
CASP-like protein 3A1, SbCASPL3A1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL32_MORMI
Sequence: MAVQKSKVTRSRRGQRRSHDALTAAATTVDVTSGETHLRHNVTADGYYKGVKVINK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: YMN4_PODAN
Sequence: MSGLLYALLIIPMIGIFFILSFDSYNFNITSNNSNSGSFSEAGAGKNSGGELLKVLVINNELNFYKKIAFITTIMNLIVSLIIYILFDFSTNQFQFVQDALELSVYNIYLGVDGLSIYFVLLTTIIMPIALISNWNSITHNIKAYLIIILLLETLLLAVFLVLDVLLFYIFFESILPPLFILIGLFGSSNKVRASFYIFLYTFNLKCKRAKYRGSPKALVTKVQHESVELAWLMTQGMVKSLVDIWVIAVLSHPCLRTESKQEGVKEQRVDGSSSSRNLEFVRCTLVAGKPVLGRKIHHCPCGPASSKLMKVQGYYNITTQAATYTHPLSTLDPWFITGFVDAEGCFMIGLTKSELYRSGYQVTAIFKISLRRTRKDYTLLCQIRDYFGIGIITKHGETTLQYMVRSIKDLNVILSHFDAYPLFSQKRSDYILFKQAIVLIKNKEHLTK
What are the official names of this protein?
Uncharacterized 50.9 kDa protein in ND4 intron 1.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: APC13_XENTR
Sequence: MDSEVLRDGRILDLIDDAWREDKLPYEDVTIPLNELPEPEQDNGGATESVKEQEMKWADLALQYLHENISSSGS
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.  The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity).
What are the official names of this protein?
Anaphase-promoting complex subunit 13, APC13, Cyclosome subunit 13.
What is the protein family that this protein belongs to?
Belongs to the APC13 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PTH_VIBCH
Sequence: MSQPIKLLVGLANPGPEYAKTRHNAGAWVVEELARIHNVTLKNEPKFFGLTGRLLINSQELRVLIPTTFMNLSGKAIAALANFYQIKPEEIMVAHDELDLPPGVAKFKQGGGHGGHNGLKDTISKLGNNKEFYRLRLGIGHPGHKDKVAGYVLGKAPAKEQECLDAAVDESVRCLEILMKDGLTKAQNRLHTFKAE
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_XANC8
Sequence: MSIVTKALNLVPMVVEQTSRGERAYDIYSRLLKERLIFLVGPIDDHMANVIVAQLLFLEADNPEKDISIYINSPGGVVTAGMAIYDTMQYIKPDVSTICVGQAASMGALLLASGAAGKRYALPNSRVMIHQPLGGFQGQATDIDIHAREILTLRSRLNEILAKHTGQSLETIARDTERDNFKSAVDAQAYGLVDHVLERRPEESIQPS
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_BACC4
Sequence: MHILVVSVNYRTAPVEFREKLTFQAAELERAMTTLQNQKSVLENVIVSTCNRTEIYAVVDQLHTGRYYIKKFLADWFQLEIEEVAPYLTIFEQDGAIDHLFRVTCGLDSMVVGETQILGQIKDSFLEAQQVKATGTIFNELFKQVITLAKRAHSETTIGESAMSVSYAAVELGKKIFGELTDCHVLILGAGKMGELALQNLYGSGARKVTVMNRTLSKAEVMAEKYMGHAKSLSELQCALLEADILISSTGASEYVITKEMMTKVEKMRSGRPLFMVDIAVPRDIDPAIDELEGSFLYDIDDLQGVVEANRAERLKEAEKIQFMIEEEIVLFKTWLSTLGVVPLISALRDKALAIQSETMVSLERKIPNLSDREKKVISKHTKSIINQLLKDPILVAKEIAAEEGASEKLALFAKIFDLETEEVESRAEEVEHKRVWTPSVPSL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: PTH_STAMF
Sequence: MLRNTEYKQVIIVRTDIKMSKGKLAVQVAHAAVSAAFEAYKKKREWFLEWWATGQKKIVVKGGSERDLLKYAEMAKKKDLPVAIIRDAGLTELPPNTLTAVGIGPGPSRKIDEITGDLKLL
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLRD1_HUMAN
Sequence: MAVFKTTLWRLISGTLGIICLSLMSTLGILLKNSFTKLSIEPAFTPGPNIELQKDSDCCSCQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDELDFMSSSQQFYWIGLSYSEEHTAWLWENGSALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYICKQQLI
What is the function of this protein?
(Microbial infection) Upon SARS-CoV-2 infection, may contribute to functional exhaustion of cytotoxic NK cells and CD8-positive T cells (PubMed:32859121).  On NK cells, may recognize HLA-E in complex with SARS-CoV-2 S/Spike protein S1-derived peptide (LQPRTFLL) expressed on the surface of lung epithelial cells, inducing NK cell exhaustion and dampening antiviral immune surveillance (PubMed:32859121).
What are the official names of this protein?
Natural killer cells antigen CD94, KP43, Killer cell lectin-like receptor subfamily D member 1, NK cell receptor.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: Y1110_STAAS
Sequence: MSEIKRLEINYKTDELFENFRAFGNKDLYMVNELNGQMIDASSDSPFYGIFVGDQLGARMALLKKGDVEEIYFPDFEDYILLWKLEVLPKYQNRGYASELIDFAKSFNMPIKAIGRNDSKDFFLHHGFTDVEAKNIEGHDVLLWKP
What are the official names of this protein?
Uncharacterized N-acetyltransferase SAS1110.
Protein: LAT1L_HUMAN
Sequence: MAGAGPKRRALAAPVAEEKEEAREKMMAAKRADGAAPAGEGEGVTLQGNITLLKGVAVIVVAIMSSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLDVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACHSVQLIVHQPTQVI
What are the official names of this protein?
Putative L-type amino acid transporter 1-like protein IMAA, hLAT1 3-transmembrane protein IMAA, hLAT1 3TM IMAA, hLAT1 3-transmembrane protein MMAA, hLAT1 3TM MMAA.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CYAA_LACKL
Sequence: MSSPTDAERVNMRREKHPQIEETFEEHVHNAMPKFKKHYALGITTHTNDEDDDPRDHRQRGIHNPNFIHSPNDPRPPLSQPIKPRFSVHGTASNASVFSHGDIAPVRKTSRAGSLFKRLAGKKSTTSLLGTEHQQRQQQQSSNSLVPAAGLRRKMSTFIHGGSGSQSNESRGTRSSIFFPSTSNSRRGSATSTMTSGSRSSHPPDTPPITSQQQEQQYDQQRQQRPETREQEQKPPTLSDMPIVSRSPSFFMLDTDLNNLSDITNIISATPKNTESDEVRSTGANKTLKYPKPPLSSHKSTSASDLSHHKAQWTAPESWDIEEDANKLLATKRKAKHHHHYHHPQHPRPPHRKHYSNFSKPIEDKAVVEKEQEPPEKCPQPISTDSNDAQGLEIAKPIDESSGIQHSASTQSVSSFSSGATGASGATGKQIGGDQETESTISTVGEDEEVTNLRSIDSEQTDDTSFSKFDEEYDKAEYQLEKYYNDFSDVDLNRRYAIRIFNIDDTFTTLSCTPNTTLQDMMPQLKRKFNVGQGSYQVSLKVGKLSKILRPTAKPILIQRRLLLLNGYLKSDPLHIMGIEDLSFIFSFVFHPVATSHLNYEQEQRLSRGDFVHVDLRNMDLTTPPIILYQHTSDIESLDVSNNANIFLPLDFIESAIKLSSLRMVNIRASKFPANVTDAYKLVSLDLERNFIKKVPDSIFKLNNLTIVNLQCNNLERLPPGFSKLKNLQLLDISSNKFVNYPEVINSCTNLLQIDLSYNKIHSLPVSINQLVKLAKMNLFNNRLTSVGDLSQMKNLRTLNLRCNRVTSIECHAPNLQNLFLTDNRISTFDDDLTRLRTLELQQNPITSMVCGGNYMANMTSLSLNKAKLSSFSAELLSKLPRLEKLELNENNLTQLPPEINKLTRLIYLSVARNKLESIPDEISDLRSLKSLDLHSNNLRMLMNNLEDLELTSLNVSSNLLTGFHGSPAKFFASPSPKLAKSLLFLSVADNNLTDSIWPLVNTFQNLKTLNLSYNNFVEISDLKLQNLTELYLSGNNFTSLPGEAVQHLRSLKVLMLNGNKLLSLPAELSQLSRLSVLDVGSNQLKYNISNYHYDWNWRNNKDLKYLNFSGNKRFEIKSALDPEGKNDLSDLGILKQLRVLGLMDVTLKTSKVPDESVSIRLRTTASMINGMRYGVADTLGQSDSVCSRDVTFERFRGREDECLICLYDGKNENASSGHKISKIIRDIYDKILIRLLEKYGEESDGIKRALRYSFLQLNKEINGMLVSVEDGNTDSGLTSADLLSGSSATVVYLKGKKIYTANIGDTMAVLSKNNGDFVTLTKLHVPAEREEYERIRTSGGYVNNQKLDGVSEVSRAVGFFDLLPHIHASPDISETVLSYSDEMLIIATHKLWEYLDYETVCDISRENKSQPMSAAEKMKDYAISYGCSDNITILCVSLDKSVNQQSQFTLNREDLISRKNTFEDTVLRRLQPEIAPPTGNVAIVFTDIKNSTFLWELFPDAMRAAIKTHNDIMRRQLRIYGGYEVKTEGDAFMVAFPTPTSALVWCLSVQLKLLEAEWPEEITSIQDGCLITDNSGTKVYLGLSVRMGVHWGCPVPEIDLVTQRMDYLGPVVNKAARVSGVADGGQITLSSDFCSEFKKIMKFHKRVVENQEPLKEVYGEDFIGEVLEREIHMLENVGWVFKDLGEQKLKGLETKEFITIAYPKTLASRHDLATKNQNSSVLNDDLLFQLRTISNKLENILSSINGGLIESETPGNSSIYMTFDKNTKDAVITKSTESDWISFLDHLVTRVESTVAILQLRQKLQGGLELYTSSDSTMHKSVFELLDEILKIQTDQKQ
What is the function of this protein?
Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP.
What are the official names of this protein?
Adenylate cyclase, ATP pyrophosphate-lyase, Adenylyl cyclase.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-3 family.
Protein: TAL_YERPB
Sequence: MTDKLTSLRQITTVVADTGDIAAMKLYQPQDATTNPSIILNAAQIPEYRKLIDEAIAWAREQSSDHAQQIIDATDKLAVNIGLEILKLIPGRISTEVDARLSYDTVASVTKAKRLIKLYNEAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFSFAQARACAEAGVFLISPFVGRILDWYKANGDQKEFAPSEDPGVVSVTEIYQYYKKHGYKTVVMGASFRNLGEIIELAGCDRLTIAPSLLKELAESEGPVERKLAYTGEIQAKPAPLTEAEFYWQHNQDPMAVDKLADGIRKFAIDQGKLEKMISDLL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DMAS1_MAIZE
Sequence: MSATGRAPCGLPRIGLGTAVQGPRPDPVRAAVLRAIQLGYRHFDTAAHYATEAPIGEAAAEAVRTGLVASREDLFVTSKVWCADAHRDRVLPALRRTLSNLQMEYVDLYMVHWPVTMKAGRFTAPFTPEDFEPFDMRAVWEAMEECHRLGLAKAIGVCNFSCKKLETLLSFATIPPVVNQVEINPVWQQRKLREFCRAKGIQLCAYSPLGAKGTHWGSDSVMDSGVLHEIAKSKGKTVAQVCLRWVYEQGDCLIVKSFDEGRMKENLDIVDWELSEEERQRISKIPQRKINQGRRYVSEHGPYKSFEELWDGEI
What is the function of this protein?
Catalyzes the reduction of a 3''-keto intermediate during the biosynthesis of 2'-deoxymugineic acid (DMA) from L-Met.  Involved in the formation of phytosiderophores (MAs) belonging to the mugineic acid family and required to acquire iron.
What are the official names of this protein?
Deoxymugineic acid synthase 1, ZmDMAS1.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: PA2HB_CALRH
Sequence: MRTLWIMAVLLLGVEGSLIELGKMIFQETGKNPVKNYGLYGCNCGVGNRGKPVDATDRCCFVHKCCYKKVTGCDPKKDRYSYSWENKAIVCGEKNPPCLKQVCECDKAVAICLRENLGTYDKKHRVTVKFLCKAPESC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that lacks enzymatic activity.  Displays myotoxic activities (By similarity).  A model of myotoxic mechanism has been proposed: an apo Lys49-PLA2 is activated by the entrance of a hydrophobic molecule (e. g.  fatty acid) at the hydrophobic channel of the protein leading to a reorientation of a monomer (By similarity).  This reorientation causes a transition between 'inactive' to 'active' states, causing alignment of C-terminal and membrane-docking sites (MDoS) side-by-side and putting the membrane-disruption sites (MDiS) in the same plane, exposed to solvent and in a symmetric position for both monomers (By similarity).  The MDoS region stabilizes the toxin on membrane by the interaction of charged residues with phospholipid head groups (By similarity).  Subsequently, the MDiS region destabilizes the membrane with penetration of hydrophobic residues (By similarity).  This insertion causes a disorganization of the membrane, allowing an uncontrolled influx of ions (i. e.  calcium and sodium), and eventually triggering irreversible intracellular alterations and cell death (By similarity).
What are the official names of this protein?
Basic phospholipase A2 homolog G6K49, svPLA2 homolog, CRV/TMV/DAV-K49.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. K49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.