PharMolix/UniProtQA huggingface dataset:
Protein: NH2L1_HUMAN
Sequence: MTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANEATKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPVIACSVTIKEGSQLKQQIQSIQQSIERLLV
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).  Involved in pre-mRNA splicing as component of the spliceosome (PubMed:28781166).  Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly (PubMed:10545122, PubMed:17412961).  The protein undergoes a conformational change upon RNA-binding (PubMed:17412961, PubMed:10545122, PubMed:28781166).
What are the official names of this protein?
NHP2-like protein 1, High mobility group-like nuclear protein 2 homolog 1, OTK27, SNU13 homolog, hSNU13, U4/U6.U5 small nuclear ribonucleoprotein SNU13, U4/U6.U5 tri-snRNP 15.5 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=Concentrated in the dense fibrillar component of the nucleolus.
Protein: LEXA_PARDP
Sequence: MLTRKQIQLLEFIQARMARDGVPPSFDEMKLALDLRSKSGIHRLVTALEERGFIRRLPHRARALEIVRLPESLSKGPGFQPRVIEGTMPDRPAPLPRGAMEVSVSAIELPVMGRIAAGVPIEAISEISHHIAVPTTMLSGQDRHYALEVRGDSMIEAGINDGDVVVIREQNAAESGDIVVALVDGYEATLKRYRRKGNMIALEAANPAYETRVLPEDKVRIQGRLVGLIRSY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: CAN15_HUMAN
Sequence: MATVGEWSCVRCTFLNPAGQRQCSICEAPRHKPDLNHILRLSVEEQKWPCARCTFRNFLGKEACEVCGFTPEPAPGAAFLPVLNGVLPKPPAILGEPKGSCQEEAGPVRTAGLVATEPARGQCEDKDEEEKEEQEEEEGAAEPRGGWACPRCTLHNTPVASSCSVCGGPRRLSLPRIPPEALVVPEVVAPAGFHVVPAAPPPGLPGEGAEANPPATSQGPAAEPEPPRVPPFSPFSSTLQNNPVPRSRREVPPQLQPPVPEAAQPSPSAGCRGAPQGSGWAGASRLAELLSGKRLSVLEEEATEGGTSRVEAGSSTSGSDIIDLAGDTVRYTPASPSSPDFTTWSCAKCTLRNPTVAPRCSACGCSKLHGFQEHGEPPTHCPDCGADKPSPCGRSCGRVSSAQKAARVLPERPGQWACPACTLLNALRAKHCAACHTPQLLVAQRRGAAPLRRRESMHVEQRRQTDEGEAKALWENIVAFCRENNVSFVDDSFPPGPESVGFPAGDSVQQRVRQWLRPQEINCSVFRDHRATWSVFHTLRPSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDDMLPCDEAGCLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLALQLSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDSAYESLGLRPRHAYSILDVRDVQGTRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRGELMPHGSSEGVFWMEYGDFVRYFDSVDICKVHSDWQEARVQGCFPSSASAPVGVTALTVLERASLEFALFQEGSRRSDAVDSHLLDLCILVFRATFGSGGHLSLGRLLAHSKRAVKKFVSCDVMLEPGEYAVVCCAFNHWGPPLPGTPAPQASSPSAGVPRASPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLTESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKAYLHVQCDCTDSFNVVSTRGSLRTQDSVPPLHRQVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASKGTHSPPLTPEVAGLHGPRPL
What are the official names of this protein?
Calpain-15, Small optic lobes homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family.
Protein: Y1423_LARHH
Sequence: MPSFDIVSEVNLVEVKNALDQSNKEITNRYDFKGSDARVELADKIMTAYADSDFQLDQVKDVLLGKLAKRDVDVRCLDYAKVEKVSGNKVKQAITVKVGVETDLAKKLVRLIKDSKLKVQASIQGDAVRVSGAKRDVLQETIAMVRKEITDFPLQFNNFRE
What are the official names of this protein?
UPF0234 protein LHK_01423.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: SEC74_SCHPO
Sequence: MDESSRIASSSALHGLDEMVSAHKPSPPLPSRRKGKSALRSALEKKNRKSKSKPKVTITSDTPKVSSQHSPVSSAYTGDSTTDLDSKSGHSSSQKLSNKVSSALKLTIPKRWRSSKSSSSQCSSPFLPTSSSNGHGDDASLNLPDKKSRPSSQSSIFLSNWSTIFSSNASPTDSQLSPTHTSTIAELAASTLSIFPSGSYAGSTFGSPSRSSIDSSTYLPRSKSVNSLSSNFSARTPASNQSSVSEDFGAAPNCDHKHNSVTLSDFALPDIDQHDTVETILEKVEFTIPKQFTPAILSQGTSSLLKLCLRKYLSVVNFKCISLDMALRKFLAVYVLPNETQQIDRVLSTFSDQYFHCNPDLYDSSDECYILTFSLMILHTDFFNIHNRQKMTRAEFISNTNLPTILPEILECFYDNITYTPFVHVEHIGCVVTSPSNEKPSLSQRLGDSQFRLTKRNTFATESDHQALQEQLTGFRINLDSILDLKKIDSVRTSIESPTRTADDLYKEFARAPFLQIVSHRSQPQAFSYHFEPSAESESTNPAIINVKVFKLGILIQNEKVRKDRLLSNREVGVILTSSQLMFFKNVYWISGLLDQLEDFKRSHSFSPCYFSPHLTSLSADYIIPLSDLVAYGDGSRIENELYSFSVKQKNQRTHVFSVTNVDELNDWLVKINFVSTFATAGLAPRERLPCVESSDKSIKASVSVLPDIYEDSDAMSKASKETRSEVLECSKVRVYIVQNRIYKLEEALRQGESKMTVQRRNAANILHLEPIQSRTRIRLARCSNTLKKNMLAQMIEIQKFKISIKFLKEDLEMDSHLQDYLRSVFPSSVMGKENASEDTILESNFRNHSNPSVRRSNLRVGKTVESVQNTKLKSVENDSGKAETETVGKNPEVVRKSPAKLPNIANIMTVNGHRYSVVELPDDFLRE
What is the function of this protein?
Guanine nucleotide exchange factor for Arf GTPases, stimulating the nucleotide exchange from the GDP-bound to the GTP-bound form.  Involved in vesicular transport (By similarity).
What are the official names of this protein?
Arf guanine nucleotide exchange factor sec74.
What are the subcellular locations of this protein?
Cytoplasm. Cell septum. Cell tip.
Protein: SELD_SALTI
Sequence: MSKQAIRLTQYSHGAGCGCKISPKVLETILHSEQAKFVDPNLLVGNETRDDAAVYDLGNGTSIISTTDFFMPIVDNPFDFGRIAATNAISDIFAMGGKPIMAIAILGWPINTLSPDIAREVTEGGRFACRQAGIALAGGHSIDAPEPIFGLAVTGVVPTERVKKNSTAQAGCKLFLTKPLGIGVLTTAEKKSLLKPEHQGLATEVMCRMNVAGAAFANIDGVKAMTDVTGFGLLGHLSEMCQGAGVQAMLCYQDIPKLPGVEEYIALGAVPGGTERNFASYGHLMGDMSREVRSLLCDPQTSGGLLLAVTPDAEDDVKATAAEFGIELTAIGELVEARGGRAMVEIR
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: Y963_MYCTU
Sequence: MLQRELTRLQNGWLSRDGVWHTDTDKLADLRALRDTLAAHPGTSLILLDTASDPRKVLAAVGVGDVDNAERVGVTMGGLNTRVSSSVGDMVKEAGIQRAKAAELRERAGWPNYDAVASIAWLGYDAPDGLKDVMHDWSARDAAGPLNRFDKGLAATTNVSDQHITAFGHSYGSLVTSLALQQGAPVSDVVLYGSPGTELTHASQLGVEPGHAFYMIGVNDHVANTIPEFGAFGSAPQDVPGMTQLSVNTGLAPGPLLGDGQLHERA
What are the official names of this protein?
Uncharacterized protein Rv0963c.
Protein: ARI5A_BOVIN
Sequence: MAPPVKGKRKQSEEGEPLDPPVSPQPDGEPRSRSPVRLEEPPEAGREREEEQEEEQAFLVSLYKFMKERHTPIERVPHLGFKQINLWKIYKAVEKLGAYELVTGRRLWKNVYDELGGSPGSTSAATCTRRHYERLVLPYVRHLKGEDDKPLPPSKPRKQYKMAKEPRGDDGATERPKKVKEEKRVDQLMPAKTKTDAPDPARLPSQETPRDGMEQRGPAAGPSLPFLGASGCPEAYKRLLSSFYCRGTHGIMSPLAKKKLLAQVSKAEALQCQEEGCRHGAGGEPQAPPAAPPLESPQSPGGPAEDSRHRLTPLEGRQAPGGGLWGETQAGPRPSAPVVTGCFHAYPSEVLKPISQRPRDLFPSLKDRVLLGPPAKEEGLPAKEPPLVWGGDAGRPSAFHKGSSRKGSLYPKPKACWVSPMTKVPAESPVPLPTFPSSPGLGHKRSLAEDSSVHGSKKLRAVSPFLKEANAQECGTKPRGPDLAVSCLLGPALPEAYRGTLLRCPLNFAGTLGPLKGQATLPFSPLVIPAFPAHLLATTAPSPMTAGLMHLPPASFDSALCHRLCPASSPWHVPPATAYTAPHFSFHLNTKL
What is the function of this protein?
DNA-binding protein that may regulate transcription and act as a repressor by binding to AT-rich stretches in the promoter region of target genes.  May act as repressor and down-regulate enhancer-dependent gene expressison.  May positively regulate chondrocyte-specific transcription such as of COL2A1 in collaboration with SOX9 and positively regulate histone H3 acetylation at chondrocyte-specific genes.  May stimulate early-stage chondrocyte differentiation and inhibit later stage differention.  Can repress ESR1-mediated transcriptional activation; proposed to act as corepressor for selective nuclear hormone receptors.  As RNA-binding protein involved in the regulation of inflammatory response by stabilizing selective inflammation-related mRNAs, such as IL6, STAT3 and TBX21.  Binds to stem loop structures located in the 3'UTRs of IL6, STAT3 and TBX21 mRNAs; at least for STAT3 prevents binding of ZC3H12A to the mRNA stem loop structure thus inhibiting its degradation activity.  Contributes to elevated IL6 levels possibly implicated in autoimmunity processes.  IL6-dependent stabilization of STAT3 mRNA may promote differentiation of naive CD4+ T-cells into T-helper Th17 cells.  In CD4+ T-cells may also inhibit RORC-induced Th17 cell differentiation independently of IL6 signaling.  Stabilization of TBX21 mRNA contributes to elevated interferon-gamma secretion in Th1 cells possibly implicated in the establishment of septic shock.  Stabilizes TNFRSF4/OX40 mRNA by binding to the conserved stem loop structure in its 3'UTR; thereby competing with the mRNA-destabilizing functions of RC3H1 and endoribonuclease ZC3H12A (By similarity).
What are the official names of this protein?
AT-rich interactive domain-containing protein 5A, ARID domain-containing protein 5A.
What are the subcellular locations of this protein?
Nucleus.
Protein: H8I01_CYRHA
Sequence: MVNMKASMFLTFAGLVLLFVVCYASESEEKEFPKEMLSSIFAVDNDFKQEERDCAGYMRECEEKLCCSGYVCSSRWKWCVLPAPWRR
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U3-theraphotoxin-Hhn1q, U3-TRTX-Hhn1q, Hainantoxin-VIII-9, HNTX-VIII-9.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 51 (Hntx-8) subfamily. Hntx-8 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS3_BIFLS
Sequence: MTDTTYDNSTELDPRIAARLKRDVKGLVAAVIQQYDTHEVLMVGYMNDEALRRTLTTGRVTFWSRSRQEYWRKGDTSGHVQYVKGVSLDCDGDALLVEVDQVGAACHTGKRSCFLEGGPLPVVEGHRPAEQQNGLS
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBID_LEPIN
Sequence: MTGKKLKEGFTTGACSAAAAKAATRLLLKGKPILEIETTLPNKRQVLFTVKRCQLEGEIATCSVVKDAGDDPDCTHGAELTARVRLTKENEIKLKGGDGVAVVTKAGLGLEIGQSAINPIPRKNIKEMILEELQGSSFNGAEVEISVPGGQEMAKKTMNERLGLIGGISILGTTGIVKPYSTAAFKASVIQAIQMAKEYGIDTIVLTTGGKSEKFAMDLLPNLNELSFIQVGDFIGTGIKTSVKESIRHTIIVGMIGKLSKMADGVMMTHRGGSSVNTTMLSTIARSIGVPEEIAIEIQNANTARHVLEICKVSGYKIITTKICEIVAEKCSKHAGTNIMISCYMVDFDGKLLGKCENFSPNVGLNL
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: MURI_FUSNN
Sequence: MAEKTQRIGIFDSGLGGTTVLKELINSLPNEDYIYYGDNGNFPYGSGKTKNELQKLTERILDFFVKNNCKLVIVACNTASTAAIDYLREKFSLPIIGIIEAGVKIASKNTKNKNIAVISTKFTAESHGYKNKAKMLDSELNVKEIACIEFAQMIETGWDTFDNRKELLNKYLSEIPKNADTLVLGCTHYPLIREDIEKNIKIKVVDPAVEIVERTIQTLTSLNLLNDKKERGRIIFFVTGETYHFKPTAEKFLGKEIEIYRIPK
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: DSG2_MOUSE
Sequence: MARSPGDRCALLLLVQLLAVVCLDFGNGLHLEVFSPRNEGKPFPKHTHLVRQKRAWITAPVALREGEDLSRKNPIAKIHSDLAEEKGIKITYKYTGKGITEPPFGIFVFDRNTGELNITSILDREETPYFLLTGYALDSRGNNLEKPLELRIKVLDINDNEPVFTQEVFVGSIEELSAAHTLVMKITATDADDPETLNAKVSYRIVSQEPANSHMFYLNKDTGEIYTTSFTLDREEHSSYSLTVEARDGNGQITDKPVQQAQVQIRILDVNDNIPVVENKMYEGTVEENQVNVEVMRIKVTDADEVGSDNWLANFTFASGNEGGYFHIETDTQTNEGIVTLVKEVDYEEMKKLDLSIIVTNKAAFHKSILSKYKATPIPITVKVKNVVEGIHFKSSVVSFRASEAMDRSSLSRSIGNFQVFDEDTGQAAKVTYVKVQDTDNWVSVDSVTSEIKLVKIPDFESRYVQNGTYTAKVVAISKEHPQKTITGTIVITVEDVNDNCPVLVDSVRSVCEDEPYVNVTAEDLDGAQNSAPFSFSIIDQPPGTAQKWKITHQESTSVLLQQSERKRGRSEIPFLISDSQGFSCPERQVLQLTVCECLKGGGCVAAQYDNYVGLGPAAIALMILALLLLLLVPLLLLICHCGGGAKGFTPIPGTIEMLHPWNNEGAPPEDKVVPSLLVADHAESSAVRGGVGGAMLKEGMMKGSSSASVTKGQHELSEVDGRWEEHRSLLTAGATHHVRTAGTIAANEAVRTRATGSSRDMSGARGAVAVNEEFLRSYFTEKAASYNGEDDLHMAKDCLLVYSQEDTASLRGSVGCCSFIEGELDDLFLDDLGLKFKTLAEVCLGRKIDLDVDIEQRQKPVREASVSAASGSHYEQAVTSSESAYSSNTGFPAPKPLHEVHTEKVTQEIVTESSVSSRQSQKVVPPPDPVASGNIIVTETSYAKGSAVPPSTVLLAPRQPQSLIVTERVYAPTSTLVDQHYANEEKVLVTERVIQPNGGIPKPLEVTQHLKDAQYVMVRERESILAPSSGVQPTLAMPSVAAGGQNVTVTERILTPASTLQSSYQIPSETSITARNTVLSSVGSIGPLPNLDLEESDRPNSTITTSSTRVTKHSTMQHSYS
What is the function of this protein?
Component of intercellular desmosome junctions.  Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
What are the official names of this protein?
Desmoglein-2.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.
Protein: Y114_METTH
Sequence: MAFHVMIIPSMNCPSDCSYCWGVDRDSRVMDMETVREMVSWLMEFRNEPATFTFHGGEPLLAGYEFYRDTLKLISERLSFLKPAFAIQTNLWLMTDEMAELFAEYSIPIGSSLDGPREINDYQRGDGYFDRTMQGYEIARKHGLRVSFISTFTSYSIRRREEIFNFFLENGMNLKLHPALPSLKSSDPEEWAITAEEYGDLLLYLLDSYLEHFGEIEIQNIDHFAKSAFLRRGLYVHMLIVWATPSQLTPTVIYTHAIASLV
What are the official names of this protein?
Uncharacterized protein MTH_114.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.
Protein: CLP1_DROWI
Sequence: MSEDNSQGRDYTLESDSELRFEIEQKDVKVLVTLVNGFAELFGTELVKKKKYEFGMGAKVAIFTYQGCVLHVQGKMDVCYVSKETPMVQYVNCHAALEQFRQEAEEKDACGPVAMVVGPMDVGKSTLCRILLNYAVRVGRRPLYADIDVGQGAIAIPGNVATILIERPASIEEGFPKTAPLVYHFGHKSPSGNSVLYNAVVSKMAEVTLNSLSGNKRTQSSGIIVNTCGWVKGSGYAHLLHAARAYGAKAIFVLDQERLYNELLRDVPPNVHVVLLPKSGGVVERSKELRHESRDQRIKEYFYGNIRAPFYPFSFEVKFQDLRLYKIGAPPLPDSCMPIGMKAEDNKTKVVAVTPTQSLLHHILALSFAENTDDDVIGTNVAGFCCVTNVDMDRQAVMLLSPQPRPLPPNALLLWSELQFMDNHA
What is the function of this protein?
Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
What are the official names of this protein?
Protein CLP1 homolog.
What is the protein family that this protein belongs to?
Belongs to the Clp1 family. Clp1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: I1B2_CONMA
Sequence: TCSNKGQQCGDDSDCCWHLCCVNNKCAHLILLCNL
What are the official names of this protein?
Conotoxin M11.2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KTNA1_ARATH
Sequence: MVGSSNSLAGLQDHLKLAREYALEGSYDTSVIFFDGAIAQINKHLNTLDDPLARTKWMNVKKAIMEETEVVKQLDAERRAFKEAPTGRRAASPPINTKSSFVFQPLDEYPTSSGGGPMDDPDVWRPPTRDVTSRRPARAGQTGTRKSPQDGAWARGPTTRTGPASRGGRGGATSKSTAGARSSTAGKKGAASKSNKAESMNGDAEDGKSKRGLYEGPDEDLAAMLERDVLDSTPGVRWDDVAGLSEAKRLLEEAVVLPLWMPEYFQGIRRPWKGVLMFGPPGTGKTLLAKAVATECGTTFFNVSSATLASKWRGESERMVRCLFDLARAYAPSTIFIDEIDSLCNSRGGSGEHESSRRVKSELLVQVDGVSNTATNEDGSRKIVMVLAATNFPWDIDEALRRRLEKRIYIPLPDFESRKALININLRTVEVASDVNIEDVARRTEGYSGDDLTNVCRDASMNGMRRKIAGKTRDEIKNMSKDDISNDPVAMCDFEEAIRKVQPSVSSSDIEKHEKWLSEFGSA
What is the function of this protein?
Severs microtubules in vitro in an ATP-dependent manner.  Required for oligomerization of functional KTN80-KTN1 complexes that catalyze microtubule severing (PubMed:28978669).  This activity may promote rapid reorganization of cellular microtubule arrays.  May be required for reorientation of cortical microtubule arrays during cellular elongation.  Failure to correctly orient these arrays drastically compromises fiber length, cell wall thickness and mechanical strength.  May also be required for the spatial organization of developmental cues within the root.
What are the official names of this protein?
Katanin p60 ATPase-containing subunit A1, Katanin p60 subunit A1, CAD ATPase, Katanin-1, AtKTN1, Katanin-like microtubule-severing protein, AtKSS, Protein BOTERO 1, Protein ECTOPIC ROOT HAIR 3, Protein FAT ROOT, Protein FRAGILE FIBER 2, AtAAA1, p60 katanin, Atp60.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
Protein: MNTP_ECOBW
Sequence: MNITATVLLAFGMSMDAFAASIGKGATLHKPKFSEALRTGLIFGAVETLTPLIGWGMGMLASRFVLEWNHWIAFVLLIFLGGRMIIEGFRGADDEDEEPRRRHGFWLLVTTAIATSLDAMAVGVGLAFLQVNIIATALAIGCATLIMSTLGMMVGRFIGSIIGKKAEILGGLVLIGIGVQILWTHFHG
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Probable manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AMPA_ALBFT
Sequence: MNFELETLDLNGAAKEKCDALIVLLATSFKPGKDNLSILVAQALKAGDLESQSGKALVLYRPTGLACARAVLANVGEGSANEVSKAVKAAVLAVKAGNVKKLVICFAALPQEAPLRAAVTAAAEASYVFTTTKSKPEGRVIQRVVVAVSNSSGFKPVFDRAVAAVTGIEFAKEWANRPANHATPALLAGAARSLAKLANIKCEVLGPKQVERLGMGAFMAVAQGSEEPLRFIVLRYDGAQKSAAPTVLLGKGITFDSGGISIKPAADMDEMKFDMSGAASVLGVFLALAQLKPAINVIGLIPSCENLLDGRSVKPGDVVTSMSGQTIEILNTDAEGRLVLCDALTYAERFKPRAVVDIATLTGACVIALGGVRSGLFSADDQLAAALVSAGESSLDLCWRLPLDDDYAEGLKTSFADVANVAGRAGGAITAAKFLQRFAGKFPWAHLDIAGTAWKSGTAKGATGRPVALLLEYLLTSAK
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LLOS_MENAQ
Sequence: MCTIISVNHHHVAILSKPKVKLFHTKNKRSASINLPWSLSPSSSAASRPISCSISSKLYTISSAQEETRRSGNYHPSVWDFDFIQSLDTDHYKEEKQLEREEELIMEVKKLLGAKMEATKQLELIDDLQNLGLSYFFRDEIKNILNSIYKIFQNNNSTKVGDLHFTSLGFRLLRQHGFNVSQGVFDCFKNEHGSDFEKTLIGEDTKGVLQLYEASFLLREGEDTLEVARKFSTEFLEEKLKAGIDGDNLSSSIGHSLEIPLHWRIQRLEERWFLDAYSRRKDMNPIIFELAKLDFNIIQATQQEELKDLSRWWNDSSLPQKLPFVRDRLVESYYWALGLFEAHKFGYERKTAAKIITLITALDDVYDIYGTLDELQLFTHVIRRWDTESATQLPYYLQLFYFVLYNFVSEVAYHILKEEGFISIPFLHRAWVDLVEGYLQEAKWYYTKYTPTMEEYLNYASITIGAPAVISQIYFMLAKSKEKPVIESFYEYDEIIRLSGMLVRLPDDLGTLPFEMKRGDVAKSIQIYMKEQNATREEAEEHVRFMIREAWKEMNTTMAANSDLRGDVVMAAANLGRDAQFMYLDGDGNHSQLQHRIANLLFKPYV
What is the function of this protein?
Monoterpene synthase that catalyzes the formation of (3R)-linalool from geranyl diphosphate, but not from farnesyl diphosphate or geranylgeranyl diphosphate.
What are the official names of this protein?
R-linalool synthase, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsb subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MIAB_FLAJ1
Sequence: MEKIIEESKQGESLVLENKPENTKKLFIESYGCAMNFSDSEVVASILSDGGYNTTSVLEEADLVLVNTCSIRDKAEQTIRKRLEKYNAVKRTNPKMKVGVLGCMAERLKSQFLEEEKIVDLVVGPDAYKDLPNLLAEVEEGRDAINVILSKEETYGDISPVRLMSNGITALVSITRGCDNMCTFCVVPFTRGRERSREPQSIMAEIQDLWSKGFKEITLLGQNVDSYLWYGGGLKKDFVNASEMQKATAVDFDQLLEMVAVGFPKMRIRFSTSNPQDMHESILHVMAKYPNICKHIHLPVQSGSNRILKEMNRLHSREEYMALIDKIRAIVPDASISQDMIAGFPTETEQDHQDTMSLMEYVKYNFGYMYSYSERPGTLAGRKMKDDVEEETKARRLQEIVDLQQKHAWFRSEEFVGKTVEVLVEKVSKKSKDEFSGRNSQSITVVFPKENYKIGDFVNVKITSCTSGTLKGEAVGLSSMN
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALEUL_ARATH
Sequence: MSVKLNLSSSILLILFAAAASKEIGFDESNPIKMVSDNLHELEDTVVQILGQSRHVLSFSRFTHRYGKKYQSVEEMKLRFSVFKENLDLIRSTNKKGLSYKLSLNQFADLTWQEFQRYKLGAAQNCSATLKGSHKITEATVPDTKDWREDGIVSPVKEQGHCGSCWTFSTTGALEAAYHQAFGKGISLSEQQLVDCAGTFNNFGCHGGLPSQAFEYIKYNGGLDTEEAYPYTGKDGGCKFSAKNIGVQVRDSVNITLGAEDELKHAVGLVRPVSVAFEVVHEFRFYKKGVFTSNTCGNTPMDVNHAVLAVGYGVEDDVPYWLIKNSWGGEWGDNGYFKMEMGKNMCGVATCSSYPVVA
What is the function of this protein?
May play a role in proteolysis leading to mobilization of nitrogen during senescence and starvation.
What are the official names of this protein?
Thiol protease aleurain-like.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: GDIB_HUMAN
Sequence: MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPGSPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVTEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQDVIDFTGHALALYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNGKVIGVKSEGEIARCKQLICDPSYVKDRVEKVGQVIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPEKEIRPALELLEPIEQKFVSISDLLVPKDLGTESQIFISRTYDATTHFETTCDDIKNIYKRMTGSEFDFEEMKRKKNDIYGED
What is the function of this protein?
GDP-dissociation inhibitor preventing the GDP to GTP exchange of most Rab proteins.  By keeping these small GTPases in their inactive GDP-bound form regulates intracellular membrane trafficking (PubMed:25860027).  Negatively regulates protein transport to the cilium and ciliogenesis through the inhibition of RAB8A (PubMed:25860027).
What are the official names of this protein?
Rab GDP dissociation inhibitor beta, Rab GDI beta, Guanosine diphosphate dissociation inhibitor 2, GDI-2.
What is the protein family that this protein belongs to?
Belongs to the Rab GDI family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: DAPA_PROM2
Sequence: MISETNFTNPLFGRILTAMVTPFNENGDVDYELAIKLSNYLFENGSDGIVLCGTTGESPTLSWSEQHDLFTAVKGSLDSSCKVIVGTGSNSTIEAIEATRKAYESGADGALVVVPYYNKPPQEGLYTHFSSIANSAKDLPLMLYNIPGRTGCNLLPDTVKKLMDFSNILSIKAASGRIEEVTELRAACGPELFIYSGDDSLLLPMMSVGAVGVVSVASHLVGTQLREMIFFFLDGEVSKALEIHEKLQPLFKGLFETTNPIPVKAALELLGWKVGSPRNPLTPLNKEQKENLSKIIKNLSL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROK_STRPC
Sequence: MTKVLLGFMGVGKTTVSKHLSMHCKDMDAIIEAKIGMSIAAFFEQHGEIAFRTIESQVLKDLLFANDNSVIVTGGGVVVLQENRQLLRKNHQHNILLVASFETLYQRLKHDKKSQRPLFLKYSKEAFYEFYQQRMVFYEGLSDLVIRVDHRTPEEVANIIEGY
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIG_PECAS
Sequence: MNVENQTPNVDHQEIAKFEAIASRWWDLEGEFKPLHRINPLRLGYISQRAEGLFGKKVLDVGCGGGILAESMAREGADVTGLDMGAEPLQVARLHALESGVTVDYVQETVEAHADAHSGLYDVVTCMEMLEHVPDPQSVVQACAKLVKPGGHVFFSTINRNAKAWMMAVIGAEYILKMVPRGTHDIKKFIRPAELMRWVDDTPLRERHITGLHYNLLTDRFKLGPNVDVNYMLHTSHDKQC
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: RS16_ANOFW
Sequence: MAVKIRLKRMGAKKSPFYRIVVADSRSPRDGRFIETIGTYNPLTEPAEIKINEELALKWLQNGAKPSDTVRNLLSKQGILEKFHNLKYGK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.