PharMolix/UniProtQA huggingface dataset:
Protein: UVRA_THET8
Sequence: MDRIVIRGAREHNLKNISLELPRGKFIVITGVSGSGKSTLAFDTIYAEGQRRYVESLSSYARQFLGVMDKPEVESIEGLSPAISIDQKTTSHNPRSTVGTVTEIHDYLRLLFARVGQAFCPECGRPIEKQSASEITDRLLKRPPGTRAILMAPLVRGRKGEYRKLFQQLLKEGYARVRVDGVIYLLEEAQGLSLEKYEKHDIDLVIDRVVLKEEERPRIAEAVELALLRGEGLLRVLYPDTGEEELFSEKFACPEHGSVLEELEPRIFSFNSPYGACPACSGLGYRQEFDPELVVNPELSLAEGAILPWSRGRDTGRSYLWDRLRALAEHLGFDLKTPFKDLPEEAKRAVLYGLPEPFEVVFRRGGKETFRVEVRYEGVIPWLEKRYQESDSEGVREALEGFMSLRPCPACGGTRYKREVLSVKVAGRNIAEVSALPVREALAFFQGLEKTLPPFQAQIARPILREIVERLGFLVDVGLDYLTLDRAANTLSGGEAQRIRLATQVGSGLTGVLYVLDEPSIGLHPRDNQRLIRTLKRLRDLGNTLIVVEHDEETMRAADWIVDMGPGAGIHGGEVVAQGTLEDILKSPQSLTGAYLRGEKRIPVPKERRKGNGKWLVLKGARAHNLKNVTLRIPLGRFVAITGPSGSGKSTLVHDVLYAALAQRLMRAKTTPGPYEALEGVEHLDKVIEIDQSPIGRTPRSNPATYTGVFDEIRDLFAKTPEARKRGYGPGRFSFNVKGGRCEACGGDGTVKIEMLFLPDLYVPCEVCKGKRYNKETLEVKLRGKSIADVLDMTVEEALDFFQNVPSIARKLQLMVDVGLGYMKLGQPSPTLSGGEAQRIKLATELGRKATGRTLYILDEPTTGLHFDDVAKLLSVLHRLVDAGNTVVVIEHNLDVVKTADWVIDLGPEGGDRGGEIVAEGTPEEVALTGSPTGAFLARIPEIAARIGVAAD
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE7_HPVME
Sequence: MHGPKPTVQEIVLELCPCNEIEPVDLVCHEQLGDSDDEIDEPDHAVNHHQHQLLARRDEQQRHTIQCTCCKCNNLLQLVVEASRENLRNVELLFMDSLNFVCPWCATETQ
What is the function of this protein?
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  E7 protein has both transforming and trans-activating activities.  Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes.  Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.  Also plays a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha.  Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
What are the official names of this protein?
Protein E7.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E7 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Predominantly found in the host nucleus.
Protein: LSPA_YERP3
Sequence: MNKPICSTGLRWLWLAVVVVILDISSKQWVMAHFALYESVPLIPFFNLTYAQNFGAAFSFLADKSGWQRWFFAGIAIGISVVLMVMMYRSTAKQRLINCAYALIIGGALGNLYDRLVHGAVNDFLDFYINNWHFPTFNLADVAISIGAVLVIFEGFLSPAEKNAVNKNE
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SOP11_ARATH
Sequence: MENNTFSSKSINLLILLLLLCTFLCQTESALPSHQELVITGRRMMSYYKPNTDIGTPSSTSDRGGGGNGRRLMSQMDVGASSSGQGGGRNRH
What is the function of this protein?
Brassicaceae-specific phytocytokine (plant endogenous peptide released into the apoplast) perceived by MIK2 in a BAK1/SERK3 and SERK4 coreceptors-dependent manner, that modulates various physiological and antimicrobial processes including growth prevention and reactive oxygen species (ROS) response regulation.
What are the official names of this protein?
Serine rich endogenous peptide 11, AtSCOOP11, Phytocytokine SCOOP11, Precursor of serine rich endogenous peptide phytocytokine 11.
What is the protein family that this protein belongs to?
Belongs to the serine rich endogenous peptide (SCOOP) phytocytokine family.
Protein: MNMA_ECODH
Sequence: MSETAKKVIVGMSGGVDSSVSAWLLQQQGYQVEGLFMKNWEEDDGEEYCTAAADLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLAEYKAGRTPNPDILCNKEIKFKAFLEFAAEDLGADYIATGHYVRRADVDGKSRLLRGLDSNKDQSYFLYTLSHEQIAQSLFPVGELEKPQVRKIAEDLGLVTAKKKDSTGICFIGERKFREFLGRYLPAQPGKIITVDGDEIGEHQGLMYHTLGQRKGLGIGGTKEGTEEPWYVVDKDVENNILVVAQGHEHPRLMSVGLIAQQLHWVDREPFTGTMRCTVKTRYRQTDIPCTVKALDDDRIEVIFDEPVAAVTPGQSAVFYNGEVCLGGGIIEQRLPLPV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis.  Sulfur is provided by IscS, via a sulfur-relay system.  Binds ATP and its substrate tRNAs.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMA_SALAR
Sequence: MTPEHLPTEQYDAQLAEKVARLQSMMAPFSGLVPEVFRSPASHYRMRAEFRLWHDGDDLYHIMFDQQTKSRIRVDSFPAASQLINTLMKAMIAGVRDNHALRHKLFQIDYLTTLSNQAVVSLLYHKKLDEEWREAATALRDALRAQGLNVHLIGRATKTKIELDQDYIDERLPVAGKEMIYRQVENSFTQPNAAMNIQMLEWALEVTKDSKGDLLELYCGNGNFSLALARNFNRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNGVREFNRLQGIDLKRYQCETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCKNLETLSQTHTVSRLALFDQFPYTHHMECGVLLTAK
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: PROB_CLAM3
Sequence: MGTASRAGIASARRIVVKVGSSSISGDNAGQIAPLVDAIASVHARGAEVVLVSSGAIATGMPFLRLDDRPADLATQQAAAAVGQSVLIFRYQESLDRYGIVAGQVLLTAGDLAAPDHRENAQRAMERLLGLRLLPIVNENDTVATHEIRFGDNDRLAALVARLVDADLLLLLSDVDALYTRPPEEPGARRIEHVGFGDELDGVEIGSTGTGVGTGGAVTKVAAARLAAEAGTGVLLTSTAQVHSALAGEHVGTWFAPRG
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CF60_DICDI
Sequence: MIKKSALITLFLVSLILGVSLSQKPFYCQAPEPTPSLNTDGLTLKMVQILTRHGDRTPLYSTLKPTMNTWDCNLGWLMVSSLNNVPGAATDVDRLFRKVYMPNREYFPGNCSDGQLTSLGFQQHLQLGQSLRQLYVDKYELLPSELSVDAASTIWVRSTDVPRTIQSVQGHLTALFPPTTVTSGSGIPIININTMDNYYENMTPNPTLCPELAVLIANTTTTPEWGEFITNTTQLKEDVMETLGISVFPGWSSLMDLFFATQCHDFPLPEGVTQDMVTQVYEAAYWQYQYQLSFPMIARLGMSTFLEEVVDNIRAFVNGTSSVKYIVFSGHDDSVGPFTNLFGLMKEWPPYASHVELELWSDEKDNYFLQFKFNGQSYTLNGCEDVMCPIDSFFETAYSILVPNYADACSNSTMTF
What is the function of this protein?
Cell-counting factor that limits the maximum size of the multicellular structure.  Does not possess acid phosphatase activity.  Cells with decreased levels of this protein form large groups while cells overexpressing this protein form small groups.
What are the official names of this protein?
Counting factor 60.
What is the protein family that this protein belongs to?
Belongs to the histidine acid phosphatase family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL2_NITEU
Sequence: MMALRKTKPTSPGRRAVIKSVNSFIYKGKPFAALTEKKKKNAGRNNSGRITVRHIGGGHKQHYRIVDFCRNKDDIPAKVERIEYDPNRSAYIALLCYADGERRYIIAAKDIEVGSYLVSGSSSPIKMGNAMPIRNIPVGSVIHCIELRPGKGAQLARSAGSSAQLMAKEGDYSQIRLRSGEIRKIHISCRATIGEVSNSEHNLQSIGKAGAIRWRGVRPTVRGVAMNPIDHPHGGGEGKTAAGRHPVSPWGTPSKGSRTRKNKRTSNMIVRSRYSKKG
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: CAS2_CAMJE
Sequence: MIEDKFMRVLLMFDVPTKSKKEQKLASKFRNNLIKLGYFMLQFSVYMRICKGLSSAKSSIENVKKILPPYGNVRALIITEKQFDKMELLLGGIVFNEKVNNETNLTLFDIDSHGEFKYKNSNNEEIQINKKQEKYHQQNLFEF
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Functions as a ssRNA-specific endoribonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: DCUP_RICM5
Sequence: MKQIINPLKGNDNKIPIWFMRQAGRYLPEYKKVRETTKNFLDFCYDVNKATEVTLQPIKRYGFDAAIIFSDILVLPHAFGWEVDFKENIGPILKQFKSQEDFKYLQINPNDKLEKVYEIIKKVKKELPSPTSLIGFAGSPWTVMSYMLEGKGKQDFKTSKKFIYENKILAEELLNFITEKTADHLINQAKSGVDVLKLFDSWSGVLAEEEFTEFVIEPTKKIVLKVKEVFPKTPIIAFPKGAGLLYEKFIKEVPIDILAVDQMVPLEKMKEWSDKVIVQGNLDPVVLLTNKEIIKEKTYKILQAMKGKNFIFNLGHGILPETPTENVEFLTEYVRLYEEKNSNSTF
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APN2_YEAST
Sequence: MSSSENTLLDGKSENTIRFLTFNVNGIRTFFHYQPFSQMNQSLRSVFDFFRADIITFQELKTEKLSISKWGRVDGFYSFISIPQTRKGYSGVGCWIRIPEKNHPLYHALQVVKAEEGITGYLTIKNGKHSAISYRNDVNQGIGGYDSLDPDLDEKSALELDSEGRCVMVELACGIVIISVYCPANSNSSEEGEMFRLRFLKVLLRRVRNLDKIGKKIVLMGDVNVCRDLIDSADTLEQFSIPITDPMGGTKLEAQYRDKAIQFIINPDTPHRRIFNQILADSLLPDASKRGILIDTTRLIQTRNRLKMYTVWNMLKNLRPSNYGSRIDFILVSLKLERCIKAADILPDILGSDHCPVYSDLDILDDRIEPGTTQVPIPKFEARYKYNLRNHNVLEMFAKKDTNKESNKQKYCVSKVMNTKKNSNIKNKSLDSFFQKVNGEKDDRIKESSEIPQQAKKRISTPKLNFKDVFGKPPLCRHGEESMLKTSKTSANPGRKFWICKRSRGDSNNTESSCGFFQWV
What is the function of this protein?
DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA.
What are the official names of this protein?
DNA-(apurinic or apyrimidinic site) endonuclease 2, AP endonuclease 2, Apurinic-apyrimidinic endonuclease 2.
What is the protein family that this protein belongs to?
Belongs to the DNA repair enzymes AP/ExoA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASIP_PIG
Sequence: MDVTRLLLATLLVCLCFFTASSHLAPEEKSKDERSLRSNSSMNLLDFPSVSIVALNKKSKKISRKEAEKRSSKKKASMKKVAQPRPPRPAPCVANRDSCKPPALACCDPCAFCQCRFFRSACSCRVLNPTC
What is the function of this protein?
Involved in the regulation of melanogenesis.  The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).
What are the official names of this protein?
Agouti-signaling protein, ASP, Agouti switch protein.
What are the subcellular locations of this protein?
Secreted.
Protein: CLPP_DINSH
Sequence: MHDPVDTYMNLVPMVVEQTSRGERAYDIFSRLLKERIVFVNGPVHDGMSQLVVAQLLHLEAENPSKEISMYINSPGGVVTSGLSIYDTMQYIKPKVSTLVVGQAASMGSLLLTAGEKGMRFSLPNSRIMVHQPSGGYQGQATDIMIHAQETQKLKDRLNQIYVKHTGQPLKKVVDALERDNFMDAEQAKEWGLIDEIVESRANEDTSK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2510_RICB8
Sequence: MLTIISSAKTLNFELIAFKGELTSPAFPKITNQLLAIVKNYSEVQLSKTMDISEKLAHLNKERFQNFEKQDSKAAIFAYAGDVFNNIQSKNLSEDAVNFLQSHLLIISGLYGALKPLDAIKPYRLEMAAKLNEINDLSKFWQDEITNYINHTLEHHKHKYLLNLASQEYSSVLNQDKLKYPIINIHFKENRNGKLATIGINAKKARGNMVNFIANNLIDSPDLLKEFSYLGYKYSSKDSLNNDLVFVK
What are the official names of this protein?
UPF0246 protein A1I_02510.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: RM28_XENLA
Sequence: MPLHKYPPALWDVLKLKDGIYARLPEHYRRSLLEKHKPYPVHWKPHGLKYRLNPKSGQRERVQDVPILPYFPPQANKGLWGGEGWVTGYHYANNDKLSARVKKVWKPQLFKRELYSEILDKKFSITVTMRTLDLIDAAYGFDFYILKTPKEDLNSKVGMDFKRAMLMRLASKDSNLYPNDPSKRDQIYNKYKEFVIPMEEAEWVGLSLEEAVEKQRLLEKKDPTPLFKVYVEELVKQIETQTLAEPAIIGKKP
What are the official names of this protein?
39S ribosomal protein L28, mitochondrial, L28mt, MRP-L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CYB_PELGE
Sequence: MAPNIRKSHPLLKMINNSLIDLPSPSNISAWWNFGSLLGICLTTQILTGLLLAMHYTADTTLAFSSVAHTCRNVQYGWLIRNLHANGASFFFICIYLHIGRGFYYGSYLHKETWNTGVILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFMIAGLTTIHLTFLHESGSNNPLGITSNCDKIPFHPYFTLKDILGFTLMLLPLTTLALFSPNLLGDPENFTPANPLITPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLILFLIPFLHKAKQRTMTFRPISQLLFWILVTNLLILTWVGSQPVEHPFIIIGQLASITYFTILLVLFPITEALENKMLNY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LGT_BACVZ
Sequence: MNEAGTPINPIAFQLGPLSVHWYGIIIGAGALLGLWMAMRESEKRGLKKDIFIDLVLFAIPIAIICARAYYVLFEWSYYSEHPGEIIKIWKGGIAIHGGLIGAIATGIVFSKVRGISFWKLADIAAPSILLGQAIGRWGNFINQEAHGEAVSRSFLESLHLPDFIINQMYIDGQYYHPTFLYESLWSFAGVVILLLLRRVNLRRGNLFLTYVIWYSIGRYFIEGMRTDSLMLTSQLRIAQVISIVLIVLAIILMIFRRMKGYADKRYADTD
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RN2B_LITPA
Sequence: GFFSTVKNLATNVAGTVIDTLKCKVTGGCRS
What is the function of this protein?
Antimicrobial activity against Gram-negative bacterium E. coli.
What are the official names of this protein?
Ranatuerin-2PL, Palustrin-2b.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Ranatuerin subfamily.
Protein: SYDND_METCA
Sequence: MRSHRCGEVNESLLGQEVGLCGWVHRRRDHGGVIFVDLRDREGLVQVVFDPDHPEPFSLAETVRSEYVIRVVGQVRARPEGTENPNLKSGRVEVLATSLEILNRSETPPFPIESDIEVNEEMRLRYRYIDLRRPVMQQRMRLRRDITRFLRNFLDHHGFYEIETPFLTKATPEGARDYLVPSRTHPHSFFALPQSPQLYKQLLMISGMDRYYQVVRCFRDEDLRADRQPEFTQLDIETSFMNEDQIMTLMEAMIRDLFRETLNEELPDPFPRMTYAEAMRRYASDKPDLRIPLELVDIADLMAGVEFKVFAGPAADPEGRVVALKLPGGGDLSRKDIDDLTRFVGIYGAKGLAYVKVNDLGAGLEGLQSPILKFMPESTIRGILERTEAQTGDLIFFGADKARIVNESMGALRVKLGQDRGLVEKGWRPLWVTDFPMFEWDEKSGRWVALHHPFTAPKCSEEQLRQNPGRALSRAYDMVLNGTEIGGGSVRIHRTEMQQTVFDLLGIGEEEAQQKFGFLLNALRYGCPPHGGLAFGLDRLVMLMSGASSIREVMAFPKTQSAWCPLIDAPAQVNDAQLHELGIRLRKNPAVEGGTVPST
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTNK_BURM1
Sequence: MTASASRPLLGCIADDFTGATDLANMLVKSGMRTVQTIGVPAESASIDADAIVVALKSRTIPAADAVAQSLAAYEWLRAQGCRQFFFKYCSTFDSTDAGNIGPVADALLDAAGGGFTIACPAFPENGRTIYRGHLFVGDVLLNESGMENHPLTPMKDANLVRVLQRQTSSKVGLIRYDTIARGAADVRACIAQLRADGVRIAIADALSDRDLYVLGEACAALPLVTGGSGIALGLPENFRRAAELAARDNAASLPRIDGTATVLAGSASKATNAQVAAWRATRPSFRIDPLAAARGEPVVDQALAFARSHLPEPVLIYATATPDEVKAVQQALGVEAAGELVERTLAAIAHGLRALGVRKFVVAGGETSGAVVQALGVKSLQIGAQIDPGVPATATIDTEPLGLALKSGNFGAVDFFDKALRALDGAA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of 3-oxo-tetronate to 3-oxo-tetronate 4-phosphate.
What are the official names of this protein?
3-oxo-tetronate kinase, 3-dehydrotetronate 4-kinase.
What is the protein family that this protein belongs to?
Belongs to the four-carbon acid sugar kinase family.
Protein: RL19_ANASK
Sequence: MLRKAIADIEAKYLRTDLPEMRAGDSVRVHTKIKEGDKERIQVFEGVVIAYRKGAPGSSMFTVRKVSYGVGVERMFPVHSPRIDKIEVVGHGGVRRSRLYFLRGLQGKAARLHQEEGPGAADAAHAAPTPA
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: ITB4_HUMAN
Sequence: MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFELEVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDGTHVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLLLLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLRSGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTRECAQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLKLTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQLLVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGGKSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFHVQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTGCGWKFEPLLGEELDLRRVTWRLPPELIPRLSASSGRSSDAEAPHGPPDDGGAGGKGGSLPRSATPGPPGEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQSEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEFVSRTLTTSGTLSTHMDQQFFQT
What is the function of this protein?
Integrin alpha-6/beta-4 is a receptor for laminin.  Plays a critical structural role in the hemidesmosome of epithelial cells.  Is required for the regulation of keratinocyte polarity and motility.  ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778).  ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760).  ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling (PubMed:28873464).
What are the official names of this protein?
Integrin beta-4, GP150.
What is the protein family that this protein belongs to?
Belongs to the integrin beta chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell membrane; Lipid-anchor. Cell junction, hemidesmosome. Note=Colocalizes with DST at the leading edge of migrating keratinocytes.
Protein: RS19_PROA2
Sequence: MPRSLKKGPFIEGKLEKRILDMNSREEKKVVKTWARSSMISPDFVGHTVAVHNGKTHVPVYISENMVGHKLGEFAPTRTYRGHAGGKAEKGGSAPKRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: V238_FOWPN
Sequence: MESTSIILRYYVAVYPPPFFKYTLSRFIKLKNAFKLLIIKLKKQIMIYREVLNTYIIQWIV
What are the official names of this protein?
Uncharacterized protein FPV238, ORF f.
Protein: RPIA_FRAT1
Sequence: MFFNKKNNQDELKKLAATEAAKSITTEITLGVGTGSTVGFLIEELVNYRDKIKTVVSSSEDSTRKLKALGFDVVDLNYAGEIDLYIDGADECNNHKELIKGGGAALTREKICVAAAKKFICIIDESKKVNTLGNFPLPIEVIPMARSYIARQIVKLGGQPVYREQTITDNGNVILDVYNLKIDNPLKLETELNQITGVVTNGIFALKPADTVIMATKDSNIVVL
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: PYRF_XYLFT
Sequence: MMNHTPLLLGIRERLIFALDVPSRTQALEWIDQLGDAISFYKIGMELLASGEYFQVLDDLASRGKRVFVDLKFFDIPATVAGVIRRLSQWPISYCTIHGWHAPMMQAATEANTSNMHLLAVTVLTSMTREDLAKMGINREPVDVVVERALAAHMAGMSGVIASGQEAAAIRHAIGSGFSIVCPGIRTNHVPHNDQQRTIGIKAAFANGADAIVVGRPIRMAQDPQAAAEAMQTEIMTALTEPST
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.