PharMolix/UniProtQA huggingface dataset:
Protein: COAX_XYLF2
Sequence: MNDWLFDLGNSRFKCASLREGVIGPVTVLPYLTETMDAFALQELPRGRVAYLASVAAPAITTHVLEVLKIHFEKVQVAATVAACAGVRIAYAHPERFGVDRFLALLGSYGEGNVLVVGVGTALTIDLLAANGCHLGGRISASPTLMRQALHARAEQLPLSGGNYLEFAEDTEDALVSGCNGAAVALIERSLYEAHQRLDQSVRLLLHGGGVASLLPWLGDVVHRPKLVLDGLAIWAAVAANV
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPG_RICRO
Sequence: MPELPEVETLKNSLKDKLIGLIIENVELKRDNLRYKLSPLLATEILNTNILDVRRRAKYLIIDFNNDYSLIVHLGMSGRFTLQSANYKTQKHDHVIFDLSNGEKLIFNDTRRFGMIYSFKTDLLEKEFFNDLGIEPFSDLLTLEYLKDKLQTKKIPIKNLIMDNRVIVGVGNIYASESLHLARIHPDKSGNDLRDDEIENLIKAIRDVLTKAITAGGTTLKDFVNGDNKPGYFTKQLKVYGREGQSCLSCSSTIIKIKHSGRSTFYCKTCQYS
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RS21_LACLS
Sequence: MSKTLVRKNESLDDALRRFKRSVTKAGTLQELRKREHYEKPSVKRKRKSEAARKRKKY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: ABT1_PONAB
Sequence: MEAEESEKAATEQEPLKGTEQTLDAEEEQEESEDAACGSKKRVVPGIVYLGHIPPRFRPLHVRNLLSAYGEVGRVFFQAEDRFVRRKKKAAAAAGGKKRSYSKDYTEGWVEFRDKRIAKRVAASLHNTPMGARRRSPFRYDLWNLKYLHRFTWSHLSEHLAFERQVRRQRLRAEVAQAKRETDFYLQSVERGQRFLAADGDPARPDGSWTFAQRPTEQELRAQKAARPGGRERARLVTAQDKARSNKGLLARIFGAPPPSESMEGPSLVRDS
What is the function of this protein?
Coud be a novel TATA-binding protein (TBP) which can function as a basal transcription activator.  Can act as a regulator of basal transcription for class II genes (By similarity).
What are the official names of this protein?
Activator of basal transcription 1.
What is the protein family that this protein belongs to?
Belongs to the ESF2/ABP1 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus.
Protein: MTEFH_ARATH
Sequence: MFMVRLKFASISHNFSTVAAKHRRVPSKYKSLAIGKAQQAITDYLHTTRSLSYTHAEQIASNASVSIRNLILKLDFSVPTFSKSLRKHLSYHPINEFEFFFESIGIDYSEVSEFLPEKKFFFSEDRTVLDAAFALSGFGFPWNKLGKLYKEERLVFVQRPGEIESRLLKFKDIGFSTVAVIGTCLAIPRTLCGGGELGSEIRCLFVKLKRLFDEFDSHHLFEENVDSWLAVSRKIRIFYDLGCENEEMWELMCRNKSLFLEYSEEALMNKAGYFCRFGVSKEDAALLILRNPAIMNFDLEKPVISVTGMLKHFGLRQDEVDAVAQKYPYVFGRNQLKNLPYVLRAIDLHERIFDILKNGNHHLLASYTLMDPDEDLEREYQEGLEELQNSRTKRHNIQKLDFLHEIGFGENGITMKVLQHVHGTAVELHDRFQILLNSGIIFSKICMLIRSAPKILNQKPHSIQDKLRFLCGEMGDSLDYLEVFPAYLCFDLENRISPRFRFHKWLVEKGFSEKSYSIASIVATSEKAFIARLYGIHPAIPKHWFERFSSRKTRDTVS
What is the function of this protein?
Transcription termination factor involved in the regulation of mitochondrial-encoded gene expression.  Essential for normal plant growth and development.
What are the official names of this protein?
Transcription termination factor MTEF18, mitochondrial, Mitochondrial transcription termination factor 18, Protein SUPPRESSOR OF HOT1-4 1.
What is the protein family that this protein belongs to?
Belongs to the mTERF family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LYSC_CALJA
Sequence: MKVLIILGLVLLSVMVQGKVFERCELARTLKRFGLDGYRGISLANWMCLAKWESDYNTRATNYNPGDQSTDYGIFQINSHYWCNNGRTPGAVNACHISCNALLQDDITEAVACAKRVVRDPQGIRAWVAWKAHCQNRDVSQYVQGCGV
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
What are the official names of this protein?
Lysozyme C, 1,4-beta-N-acetylmuramidase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
Protein: YCEI_SHIBS
Sequence: MKKSLLGLTFASLMFSAGSAVAADYKIDKEGQHAFVNFRIQHLGYSWLYGTFKDFDGTFTFDEKNPAADKVNVTINTTSVDTNHAERDKHLRSADFLNTAKYPQATFTSTSVKKDGDELDITGDLTLNGVTKPVTLEAKLIGQGDDPWGGKRAGFEAEGKIKLKDFNIKTDLGPASQEVDLIISVEGVQQK
What are the official names of this protein?
Protein YceI.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family. Type 1 subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: METK_BURMS
Sequence: MANDYLFTSESVSEGHPDKVADQISDAILDAILAQDKYSRVAAETLCNTGLVVLAGEITTTANIDYIQIARDTIKRIGYDNTDYGIDYRGCAVLVAYDKQSPDIAQGVDRAHDNNLDQGAGDQGLMFGYACDETPELMPLPIHLSHRLVERQANLRRDGRLPWLRPDAKSQVTVRYVDGKPHSIDTVVLSTQHAPEIDLPALREAVIEEVIKPTLPADLIKGDIKFLVNPTGRFVIGGPQGDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLASRALIQVSYAIGVAEPTSVMVNTFGTGRVSDETITKLVREHFDLRPKGIIQMLDLLRPIYEKTAAYGHFGREEPEFSWEAADKALALAEAAGVEPAVQVA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PXPA_STAAT
Sequence: MRVDLNCDLGEAFGNYSFGGDHQIIPLITSANVACGFHAGDENVMNETVKLAKAHNVAVGAHPGLPDLKGFGRRNIDISNDEIYNLMIYQLGALQGFCRIHQVKINHVKPHGALYQMGAKDREIANVIAQAVYDFDPSLVLVGLANSYLISEAKNVGLITASEVFADRRYEDDGQLVSRKESDAVITDTDEALKQVLKMVKENKVISKNNKEVTLQADTICVHGDGEHALLFVSKIREILMKEGIDIQSL
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: YO075_YEAST
Sequence: MSQQENGDVATELIENRLSFSRIPRISLHVRDLSIVASKTNTTLVNTFSMDLPSGSVMAVMGGSGSGKTTLLNVLASKISGGLTHNGSIRYVLEDTGSEPNETEPKRAHLDGQDHPIQKHVIMAYLPQQDVLSPRLTCRETLKFAADLKLNSSERTKKLMVEQLIEELGLKDCADTLVGDNSHRGLSGGEKRRLSIGTQMISNPSIMFLDEPTTGLDAYSAFLVIKTLKKLAKEDGRTFIMSIHQPRSDILFLLDQVCILSKGNVVYCDKMDNTIPYFESIGYHVPQLVNPADYFIDLSSVDSRSDKEEAATQSRLNSLIDHWHDYERTHLQLQAESYISNATEIQIQNMTTRLPFWKQVTVLTRRNFKLNFSDYVTLISTFAEPLIIGTVCGWIYYKPDKSSIGGLRTTTACLYASTILQCYLYLLFDTYRLCEQDIALYDRERAEGSVTPLAFIVARKISLFLSDDFAMTMIFVSITYFMFGLEADARKFFYQFAVVFLCQLSCSGLSMLSVAVSRDFSKASLVGNMTFTVLSMGCGFFVNAKVMPVYVRWIKYIAFTWYSFGTLMSSTFTNSYCTTDNLDECLGNQILEVYGFPRNWITVPAVVLLCWSVGYFVVGAIILYLHKIDITLQNEVKSKQKKIKKKSPTGMKPEIQLLDDVYHQKDLEAEKGKNIHITIKLEDIDLRVIFSAPFSNWKEGNFHHETKEILQSVNAIFKPGMINAIMGPSGSGKSSLLNLISGRLKSSVFAKFDTSGSIMFNDIQVSELMFKNVCSYVSQDDDHLLAALTVKETLKYAAALRLHHLTEAERMERTDNLIRSLGLKHCENNIIGNEFVKGISGGEKRRVTMGVQLLNDPPILLLDEPTSGLDSFTSATILEILEKLCREQGKTIIITIHQPRSELFKRFGNVLLLAKSGRTAFNGSPDEMIAYFTELGYNCPSFTNVADFFLDLISVNTQNEQNEISSRARVEKILSAWKANMDNESLSPTPISEKQQYSQESFFTEYSEFVRKPANLVLAYIVNVKRQFTTTRRSFDSLMARIAQIPGLGVIFALFFAPVKHNYTSISNRLGLAQESTALYFVGMLGNLACYPTERDYFYEEYNDNVYGIAPFFLAYMTLELPLSALASVLYAVFTVLACGLPRTAGNFFATVYCSFIVTCCGEALGIMTNTFFERPGFVVNCISIILSIGTQMSGLMSLGMSRVLKGFNYLNPVGYTSMIIINFAFPGNLKLTCEDGGKNSDGTCEFANGHDVLVSYGLVRNTQKYLGIIVCVAIIYRLIAFFILKAKLEWIKW
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein/permease YOL075C.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYD_SHEWM
Sequence: MRSQYCGDVNKSHVGQEVTLVGWVNRSRDLGGVVFLDLRDREGIVQVVYDPDLPEVFDVASTLRSEFCVQVTGLVRARPDSQVNQDMRTGGIEILGKGLTILNSSAPLPINMDKNQHNTEEQRLKYRYLDLRRPEMADRIVFRSKVTSAVRRFLDDSGFLDIETPILTKATPEGARDYLVPSRTYKGQFFALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDIETSFMSSEQVMAKTEEMVRGLFNDLLNVDLGEFPKMTFAEAMRRFGSDKPDLRNPLELIDIADIVKEVEFAVFNGPANDPEGRVAVLSIPGGAKLSRKQLDEYAKYVTIYGAKGLAWMKVNDLDQGMEGIQSPVLKFLSEDVVKALLDRTGAQTGDLILFGADKANIVAEAMGALRLKAGEDFDLLQGEWKPLWVVDFPMFERTSDGGLHAMHHPFTAPTGISPEQLEADPTAAISDAYDMVLNGCELGGGSVRIHNSEMQSAVFRILGIEEEEANEKFGFLLEALRYGTPPHAGLAFGLDRIIMLMTGASSIRDVMAFPKTTTAACPLTNAPGFANPAQLIELGIEVIENQESKEEQA
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_ECOLC
Sequence: MHDANIRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSLLGSDAGELAGAGKTGVTVQSSLDAVKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIGTTGFDEAGKQAIRDAAADIAIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHHRHKVDAPSGTALAMGEAIAHALDKDLKDCAVYSREGHTGERVPGTIGFATVRAGDIVGEHTAMFADIGERLEITHKASSRMTFANGAVRSALWLSGKESGLFDMRDVLDLNNL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_SHIF8
Sequence: MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFEPRQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAWKNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLGQALMTPDTDEYYNAAAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: Y511_METAC
Sequence: MSKINKEIAIFIVFLILVALWGLFVKVPVEETKTPDPESQVSGMTIQFKDGISESEVRTILQNCNMTRNYRMTYDNSSEDYYIMADKDNWSDIRRELVDEMKETNKKNWTVSTPAHVIRKEDYYVLPISGQAIKDEKFLAILDKYDIGVEKFLWCDISFLYSDGPLTYWIPKEDAIRIKNELEQNDNIFSVQFDYLFPPFDPTT
What are the official names of this protein?
UPF0228 protein MA_0511.
What is the protein family that this protein belongs to?
Belongs to the UPF0228 family.
Protein: PYRG_CHLP8
Sequence: MARPKNVKHIFVTGGVISSLGKGILSASLGMLLKSRGLRVAIQKYDPYINVDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFLDEPTSQASNLTMGRVYKSVIDKERRGEYLGGTVQVVPHVIDEIKEKMNDLAKNGSLDVLITEIGGTIGDIESLPFLEAMRQLKLELGDRNVLNIHLTFVPYIKAASELKTKPTQHSVKMLLETGIQPDILVCRSEKPLSREIKNKVGHFCNVHEQDVIGLNDCETIYAVPLMLLREQLDLRVMKKLGLKKFREPNLEHWKRFCEKVTNPKDGEITIGVCGKYTEYPDAYKSIIEAFIHAGASNDVKVSVKMLRAEDAEDSSFNMNKAFEGVSGLLVAPGFGDRGIEGKVQFVQYARENNIPFFGICLGMQCASIEFARNVCDLPDANSTEFNKRARFPVIDLMEQQKKVKEKGGTMRLGSYPCILKEGSKVHEVYGKFLINERHRHRYEFNNQFRKLFEEKGMIFSGTSPNGELVEIIELKEHRWFVAVQFHPELKSRVQKVHPLFDGFVQAAKEFAMGKRQLTLEDELPRLSSEEMEGAG
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: NU4M_PANPA
Sequence: MLKLIIPTIMLLPLTWFSKKRMIWINTTTHSLIISTIPLLFFNQINNNLFSCSLSFSSDPLTTPLLMLTAWLLPLTIMASQRHLSNEPPSRKKLYLSMLISLQISLIMTFSATELIMFYIFFETTLIPTLAIITRWGNQPERLNAGTYFLFYTLVGSLPLLIALIYTHNTLGSLNILLLTLTAQELSNTWANNLMWLAYTMAFMVKMPLYGLHLWLPKAHVEAPIAGSMVLAAVLLKLGGYGMMRLTLILNPLTKHMAYPFLMLSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVVTAILIQTPWSFTGAVILMIAHGLTSSLLFCLANSNYERTHSRIMILSQGLQTLLPLMAFWWLLASLANLALPPTINLLGELSVLVTSFSWSNTTLLLTGFNMLITALYSLYMFTTTQWGSLTHHINNMKPSFTRENTLMFMHLSPILLLSLNPDIITGFTS
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DDX47_HUMAN
Sequence: MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEKKKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR
What is the function of this protein?
Required for efficient ribosome biogenesis (By similarity).  May have a role in mRNA splicing (PubMed:16963496).  Involved in apoptosis (PubMed:15977068).
What are the official names of this protein?
Probable ATP-dependent RNA helicase DDX47, DEAD box protein 47.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Localizes in the nucleolar- organizing region during ribosome biogenesis.
Protein: HIS2_SHISS
Sequence: MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDKTIESGKVTFFSRTKQRLWTKGETSGNFLNVVNIAPDCDNDTLLVLANPIGPTCHKGTSSCFGDTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALAATVHDRFELTNEASDLMYHLLVLLQDQDLDLTTVIENLRKRHQ
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisIE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AQP2_MOUSE
Sequence: MWELRSIAFSRAVLAEFLATLLFVFFGLGSALQWASSPPSVLQIAVAFGLGIGTLVQALGHVSGAHINPAVTVACLVGCHVSFLRAAFYVAAQLLGAVAGAAILHEITPVEIRGDLAVNALHNNATAGQAVTVELFLTMQLVLCIFASTDERRSDNLGSPALSIGFSVTLGHLLGIYFTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAVIGSLLYNYLLFPSTKSLQERLAVLKGLEPDTDWEEREVRRRQSVELHSPQSLPRGSKA
What is the function of this protein?
Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient (PubMed:10191086).  Plays an essential role in renal water homeostasis (PubMed:16641094).
What are the official names of this protein?
Aquaporin-2, AQP-2, ADH water channel, Aquaporin-CD, AQP-CD, Collecting duct water channel protein, WCH-CD, Water channel protein for renal collecting duct.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Note=Shuttles from vesicles to the apical membrane. Vasopressin-regulated phosphorylation is required for translocation to the apical cell membrane (PubMed:16735444). PLEKHA8/FAPP2 is required to transport AQP2 from the TGN to sites where AQP2 is phosphorylated.
Protein: ANFB_PIG
Sequence: MGPRMALPRVLLLLFLHLLLLGCRSHPLGGAGLASELPGIQELLDRLRDRVSELQAERTDLEPLRQDRGLTEAWEAREAAPTGVLGPRSSIFQVLRGIRSPKTMRDSGCFGRRLDRIGSLSGLGCNVLRRY
What is the function of this protein?
May affect cardio-renal homeostasis.  Able to promote the production of cGMP although its potency is very low compared to brain natriuretic peptide 32.
What are the official names of this protein?
Natriuretic peptides B, Brain natriuretic factor prohormone, preproBNP, proBNP, Gamma-brain natriuretic peptide, Iso-ANP.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted. Note=Detected in blood. SUBCELLULAR LOCATION: [Brain natriuretic peptide 32]: Secreted. Note=Detected in blood.
Protein: PVK2_HOPGR
Sequence: GASGLIAFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: THIE_HAEIG
Sequence: MKNIQKILPLYFVAGTQDCRHLGENLSENLLFVLKQALEGGITCFQFRDKGKFSLEHTPSAQKALAINCRDLCREYGVPFIVDDNVDLALAIEADGIHVGQSDMPVQEIRAKTDKPLIIGWSVNRLDEAKIGENLAEIDYFGIGPIFPTQSKENPKPTLGMAFIQTLRNAGITKPLVAIGGVKLAHVKTLREFGADGVAVITAITHADNVQAATKALREASDEYAK
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: Y1376_HAEIN
Sequence: MHNLIFAILCSVAVSVLLKIARKKNIIIEQAIAFNYITAITFSYFLLKPDFKGLEFTDYIAQSENSPIFLALGLLLPSVFIIMSKAVEFAGIVRSDAAQRLSLFLPILAAFLIFHETLSQSKIIGVVLAFIGLFCLLTKPTQGQSAVNFKGVLGLIGVWFGYGIIDILFKQVAKSGGAFPATLFISFSLAACVMFIYLFLKRVQWTSSSVIGGIVLGVLNFFNILFYIKAHQSFAGNPTLVFAGMNIGVICLGTITGALVFKERISKLNWLGIIFSLSAIFCLYYLDKIIA
What are the official names of this protein?
Uncharacterized protein HI_1376.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y489_YERPY
Sequence: MNKQPEDWLDDVPENKNDDDDEIIWVSKSEIKRDAEALKDLGTELVDLGKNALERIPLDEDLLAAIELAQKIKKEGRRRQIQLIGKMLRARDVEPIQTALDKLKNRHNQQVSLFHKLETLRDRLIAEGDDAIPTVLELYPDADRQQLRSLVRNAQKEQAANKPPKSFRQIFSYLRELAEKQQ
What are the official names of this protein?
UPF0307 protein YPK_0489.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: GLSA_BORA1
Sequence: MKIDVSRLSAAVNDAHARHAQAPGGANASYIPYLAKVPSHLAGVAAVTVDGDQVVAGDADYAFAIESISKVCSLVQALEDHGPDAVREKIGADPTGLPFNSVMALALHDGKPLSPLVNAGAIATVSFLKAANAEERWKKILAMQSALAGADIALSDEVNQSEQTTNFHNRAIAWLLYSASTMYSDPMEACEVYTRQCSTLFTARHLATMAATLAAKGRNPLTGKQVLKPEHVPSVLAEMMMEGLYERSGDWAYMVGLPGKSGVGGGIMAVVPGVMGLAAFSPPLDPAGNSVRGQLMVADVARTLGLNLFDRA
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: FABV1_VIBCH
Sequence: MIIKPKIRGFICTTTHPVGCEANVKEQIAYTKAQGPIKNAPKRVLVVGSSSGYGLSSRIAAAFGGGAATIGVFFEKPGTDKKPGTAGFYNAAAFDKLAHEAGLYAKSLNGDAFSNEAKQKAIELIKQDLGQIDLVVYSLASPVRKMPDTGELVRSALKPIGETYTSTAVDTNKDVIIEASVEPATEQEIADTVTVMGGQDWELWIQALEEAGVLAEGCKTVAYSYIGTELTWPIYWDGALGRAKMDLDRAATALNEKLAAKGGTANVAVLKSVVTQASSAIPVMPLYIAMVFKKMREQGVHEGCMEQIYRMFSQRLYKEDGSAPEVDDHNRLRLDDWELRDDIQQHCRDLWPQITTENLRELTDYDMYKEEFIKLFGFGIEGIDYDADVNPEVEFDVIDIE
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the NADH-dependent reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).  It can use both crotonyl-CoA and crotonyl-ACP.
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH] 1, ENR 1, Trans-2-enoyl-CoA reductase [NADH], TER.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: RUGC_GLARU
Sequence: GILDSFKQFAKGVGKDLIKGAAQGVLSTMSCKLAKTC
What is the function of this protein?
Has antibacterial activity against Gram-positive bacteria.
What are the official names of this protein?
Rugosin-C.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NRDR_RENSM
Sequence: MYCPFCRHPDSRVVDSRVSDDGSSIRRRRQCPQCERRFTTVETTSLTVIKRSGIGEPFSRGKVINGVRKACQGRPVSEDDLAVLAQEVEENIRASGAAEIEAHEVGLAILGPLQKLDKIAYLRFASVYQAFESLDDFEHAIEILRHEADLDGSAESAKKQVRP
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RIBL_METLZ
Sequence: MKKIVATGTFDILHPGHIYYLEESKKLGDELWVIVAREKNVVHKPRPIVSEDQRLKMIQSLKCVDHAVLGDQTDMYKPIREIDPAVITIGFNQKWSEEKLRADLAERNICADVVRISEYTGMPFTSSTKIIDEAVRRRTK
What is the function of this protein?
Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
What are the official names of this protein?
FAD synthase, FMN adenylyltransferase, Flavin adenine dinucleotide synthase.
What is the protein family that this protein belongs to?
Belongs to the archaeal FAD synthase family.
Protein: Y988_STRMU
Sequence: MIGSVLYLVNSQMDTLSIITWLLVILPFPILGTLFLIYTKQDWGYRELKSLIKKSTQAIKPYFQYDQRILYKLKESHARTYNLAQYLHRSGGFPVYKNTKVTYFPNGQSKFEEMKKQLLKAEKFIFLEYFIIAEGLMWGEILSILEQKVQEGVEVRVMYDGMLELSTLSFDYAKRLEKIGIKAKVFSPITPFVSTYYNYRDHRKILVIDNKVAFNGGINLADEYINQIERFGYWKDTAVMLEGEGVASFTLMFLQMWSTTNKDYEFAPYLTQNFHEIVANGYVIPYSDSPLDHEKVGENVYIDILNQARDYVYIMTPYLILDSEMEHALQFAAERGVDVKIIMPGIPDKKVPFALAKRYFPALLDAGVKIYEFTPGFVHAKVFIADDIKAVVGTINLDYRSLYHHFECATYMYQTDCLVDIKADFKETLKQSRRVTRSTLQKEKISTKLIGLVVKLVAPLL
What are the official names of this protein?
Uncharacterized protein SMU_988.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ORFD_PSHV1
Sequence: MSSAMGAVRPRRRQRRGIATTQLAAGRERRDEDDDAVKLRGEMVYVSSGTIAYSAWMFETIFGAGGSGAYSVAERPVMLTRVGEGLESCSCSYMGLTLYPVKTEQAGRMKRLAYRETLEPCVDCDAPGEQMAGGAVADEAYEDEDGADVCTIGVLENGTEAWPYHEVFFFPIVPTLDRWWPCVPSPALFLAIAKLATARLVARRRENGEPNGTTPSVHPLFYSTRVEAPPGSKELFLSTRELLGPLYDPLFDATEEDAGLLGIGTVVNANDFQAGVGLAFRPYDERSREEKQAVAAELRTLICGILDEDIGPGPCYVIVDRGPVRRRTSFYAAAGFKYTSVFEPAGSGKTKCHSVRLLNSALKPLL
What are the official names of this protein?
Uncharacterized protein ORFD.