PharMolix/UniProtQA huggingface dataset:
Protein: SBNA_STAAN
Sequence: MIEKSQACHDSLLDSVGQTPMVQLHQLFPKHEVFAKLEYMNPGGSMKDRPAKYIIEHGIKHGLITENTHLIESTSGNLGIALAMIAKIKGLKLTCVVDPKISPTNLKIIKSYGANVEMVEEPDAHGGYLMTRIAKVQELLATIDDAYWINQYANELNWQSHYHGAGTEIVETIKQPIDYFVAPVSTTGSIMGMSRKIKEGHPNAQIVAVDAKGSVIFGDKPINRELPGIGASRVPEILNRSEINQVIHVDDYQSALGCRKLIDYEGIFAGGSTGSIIAAIEQLITSIEEGATIVTILPDRGDRYLDLVYSDTWLEKMKSRQGVKSE
What is the function of this protein?
Catalyzes the synthesis of N-((2S)-2-amino-2-carboxyethyl)-L-glutamate (ACEGA) from O-phospho-L-serine and L-glutamate.  Involved in the biosynthesis of L-2,3-diaminopropionic acid (L-Dap), a precursor of staphyloferrin B and antibiotics.
What are the official names of this protein?
N-(2-amino-2-carboxyethyl)-L-glutamate synthase, ACEGA synthase.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family. SbnA subfamily.
Protein: RNZ_STRS2
Sequence: MQIQFLGTGAGQPSKARNVSSLALKLLDEINQVWLFDCGEGTQNRILETTIRPRKVAKIFITHLHGDHIFGLPGFLSSRSFQSSEEQTDIDIYGPVGIRSFVLASLKVSGTRLPYRIHFHEFDVDTVGQVLETDKFTVFAEKLDHTIPCVGYRVIQKDLEGTLDAEALRAAGVPFGPLFGKIKNGQNVTLEDGTEIIASDYISPPRPGKVVTILGDTRKCHASVRLAVNADVLVHEATYGKGDEKIARKHGHSTNMEAAQVAKDAGVKQLLLNHISPRFLSKDISQLRKDASTIFEQVHIVKDLEEIEL
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: CDC62_HALSA
Sequence: MTPDSSPSSVDDPLFESGHRIFANKDLLKIGHVPEADRIVGRDEEISKLAKRLNGAVHGYSPENVMIYGKTGTGKSLVSKHVCQRAQNAAQDGVEIGTAYIDCAEDNTETQAISSLAAKLNNESSTGISVPHTGLSTSKYYKLLWKTLDAQFDSVIIILDEIDLMNDDSVLMKLSRAEEAGKIDCSVGVIAISNKIQYVDNVNERVKSSFQHKELFFKPYDANQLREIMFNREDFSSSTTTYSISWPGWTASSCSRARFKAATF
What is the function of this protein?
Involved in regulation of DNA replication.
What are the official names of this protein?
ORC1-type DNA replication protein 2.
What is the protein family that this protein belongs to?
Belongs to the CDC6/cdc18 family.
Protein: HIS1_SALRD
Sequence: MLQIALPNKGALADGAVTLADEAGYNCRRRGRELSVRDPDYGVEFVFLRPRDIATYVSKGIIDLGVTGLDLTYDSGADVTHVLDLGFGAARFCYAAPKSSDLTPDAFTADTRIATSYDTLVRRDLEQRGVDARVISLDGAVEISIQLGVADVIADVVQTGRTIDEAGLATIGAPILNTEAVLVAQNGHTMEKDAAQHFAERVKGIIVAREYVVVEYDLPEEHLPEARKITPGIESPTVSPLNKDGWVAVKAMIERESVNAVMDDLTELDARGIIVTDIRTCRM
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMM_ECO55
Sequence: MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIYECYQPDDGDKLIRELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGELRVEVADTNESKELLKFCRKFTVPLRAALRDAGVLANYETPKRPVVHVFFIAPGCCYTGYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINAQIQARQLYHDREEVTVHVRRIWAAVGGRRDER
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSA_FRAP2
Sequence: MKIANFEVGNGKPFFLMSGPCVIESEQMAMDTAGYLAEVTKDLGINFVYKSSFDKANRSSINSFRGLGVDKGLEILAKVKKTYNVPVVTDVHEDTPFAEVAEVVDVMQTPAFLCRQTNFILDVCKQGKPVNIKKGQFLAPWDMQHVVAKAKSTGNEQIMVCERGVSFGYNNLVSDMRSLEIMKSTGCPVVFDATHSVQLPGGQGSSSGGQREFVPVLSKAAMAVGIDGLFMETHPKPAEALSDGPNSFPMYKIKEFLSLLKELDHLVKSQPKIEL
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LASP1_PIG
Sequence: MNPNCARCGKIVYPTEKVNCLDKFWHKACF
What is the function of this protein?
Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities.  Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity).
What are the official names of this protein?
LIM and SH3 domain protein 1, LASP-1, Cysteine-rich peptide ZF-1.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Note=Associated with the F-actin rich cortical cytoskeleton.
Protein: TRHO_ECO7I
Sequence: MPVLHNRISNDALKAKMLAESEPRTTISFYKYFHIADPKATRDALYQLFTALNVFGRVYLAHEGINAQISVPASNVETFRAQLYAFDPALEGLRLNIALDDDGKSFWVLRMKVRDRIVADGIDDPHFDASNVGEYLQAAEVNAMLDDPDALFIDMRNHYEYEVGHFENALEIPADTFREQLPKAVEMMQAHKDKKIVMYCTGGIRCEKASAWMKHNGFNKVWHIEGGIIEYARKAREQGLPVRFIGKNFVFDERMGERISDEIIAHCHQCGAPCDSHTNCKNDGCHLLFIQCPVCAEKYKGCCSEICCEESALPPEEQRRRRAGRENGNKIFNKSRGRLNTTLGIPDPTE
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs, the first step in 5-carboxymethoxyuridine (cmo5U) biosynthesis.  May be part of an alternate pathway, which is able to bypass cmo5U biogenesis in a subset of tRNAs under aerobic conditions.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: ALR_DESRM
Sequence: MKEPIWAEINLEAIRHNIKEIRKMVGPNREIMAVVKANGYGHGAVPVARVALEAGATRLAVARLSEAQELRRAGLKVPILLLGYISPDQIGDALEYNVTLTVFRFDLAKKIAAIAQGRGQRATVHLKVDTGMGRIGFTPDEEGLAEITAVCALNGLDVEGIYTHFATADEQDKSYTRWQFKRFMLVLNRLEEQGITFSLRHCANSAAIMEFPETYLDLVRPGIILYGLYPSEEVDKGKLLLQPAMTLKARITHVKKVNSGTKISYGCTYTVPQETDIASLPLGYADGYPRLLSSKGQVLVKGKRARVVGRVCMDQCMVDVGHIAEVKVHDEVIIFGGAELPVEEVATWLGTINYEVVCWVGSRVPRVYIG
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: OSPD3_SHIFL
Sequence: MPSVNLIPSRKICLQNMINKDNVSVETIQSLLHSKQLPYFSDKRSFLLNLNCQVTDHSGRLIVCRHLASYWIAQFNKSSGHVDYHHFAFPDEIKNYVSVSEEEKAINVPAIIYFVENGSWGDIIFYIFNEMIFHSEKSRALEISTSNHNMALGLKIKETKNGGDFVIQLYDPNHTATHLRAEFNKFNLAKIKKLTVDNFLDEKHQKCYGLISDGMSIFVDRHTPTSMSSIIRWPDNLLHPKVIYHAMRMGLTELIQKVTRVVQLSDLSDNTLELLLAAKNDDGLSGLLLALQNGHSDTILAYGELLETSGLNLDKTVELLTAEGMGGRISGLSQALQNGHAETIKTYGRLLKKRAINIEYNKLKNLLTAYYYDEVHRQIPGLMFALQNGHADAIRAYGELILSPPLLNSEDIVNLLASRRYDNVPGLLLALNNGQADAILAYGDILNEAKLNLDKKAELLEAKDSNGLSGLFVALHNGCVETIIAYGKILHTADLTPHQASKLLAAEGPNGVSGLIIAFQNRNFEAIKTYMGIIKNENITPEEIAEHLDKKNGSDFLEIMKNIKS
What is the function of this protein?
Effector protease that disrupts necroptosis in host cells by mediating proteolytic cleavage of host RIPK1 and RIPK3.
What are the official names of this protein?
Effector protease OspD3.
What is the protein family that this protein belongs to?
Belongs to the Toxin_15 family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the type III secretion system (TTSS).
Protein: CHLB_ANGEV
Sequence: MKLAYWMYAGPAHIGTLRVASSFKNVHAIMHAPLGDDYFNVMRSMLERERDFTPVTASIVDRHVLARGSQEKVIDNITRKDKEQRPDLIVLTPTCTSSILQEDLQNFVARASISSDSDVILADVNHYRVNELQAADRTLEQIVRYFLNKARRQGVLTRSLTDTPSANIIGIFTLGFHNQHDCRELKRLLQDLGIKVNQVIPEGGSVEHLQDLPKAWFNIVPYREVGLMTAKYLEREFGMPYLSTTPMGIVDTAEFIRQMEKYVNSFLSKEKVNYESYINYQTQFVSQAAWFSRSIDCQNLTGKKVVVFGDATHAASITKILVREMGIHVGCAGTYCKHDAEWFNEQVQGFCDEALITEDHTEVADTIARIEPSAIFGTQMERHIGKRLEIPCGVISSPVHIQNFPLGYRPFLGYEGTNQIADSVYNSFTLGMEDHLLDIFGGHDTKEVITKSLSTETDLTWNPESQRELNKIPGFVRGKIKRNTEKFARQEGITTITVDVMYAAKEALST
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PDXJ_CHLT3
Sequence: MRLAVNIDHIATLRNARQETQPDPVTAARLAELSGASGIVCHLREDRRHIKDRDLELLRATVQTKLDLEMAMTKEMKAIAIKTKPDLVTLVPEKRQELTTEGGLDVITRKDDLIPYIDELQQHGIPTSLFIEPTPEAITVATEVGAAFVELHTGKYSLLKSPKEIEAELLRLQDAASLAKKFGLRVVAGHGLNYENTAEIKRIKEIEEVSIGHALIARATLMGMSEAVKEMIRLLQ
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_DEHM1
Sequence: MRILVSNDDGIYSSGLWALVKRLKEVGEVVVVAPDREQSATGTQVTLRQPLRVQKTHPLIPGIEAYSVEGSPCDCVIMGLAKLITEPVDLVVSGINHGLNLGDDVLISGTVGAALQGYLRNIPSIAISIPVTAEEPENLDSAACITAEIARRIQSGHISKNSFLNINTPDLPLCRINELRVTPLAHKTHIETVEEGHDGRKRYFWLRRRQLSPADNNETDIWAVENGLISISALHERLFQQPPFMLEDTETAGILASARALQDII
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_GEOSL
Sequence: MTRKAVVLYSGGLDSTTCLAIARAEGFEPHAMSFSYGQRHSVELELAKRNARPAGAVEHMVVEFDLRKVGGSALTADIAVPKEGVGDDIPVTYVPARNTIFLSFALGWAEVLGAFDIFIGVNALDYSGYPDCRPEYISAFETMANLATRVGVEGTGRFRIHAPLMRLTKAEIIRKGLALGVDYGLTHSCYDPSPAGVACGLCDSCRLRLKGFAEVGVADPVPYVTGGQGLGGGKETP
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RN181_DROME
Sequence: MSDYFEELGHEPTGPLGANDLARNLKRLQVLAIMNGIDMEIEVPEASKRAILELPVHEIVKSDEGGDLECSVCKEPAEEGQKYRILPCKHEFHEECILLWLKKTNSCPLCRYELETDDPVYEELRRFRQDEANRRERENTLLDSMFG
What is the function of this protein?
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF181 homolog, RING finger protein 181 homolog, RING-type E3 ubiquitin transferase RNF181 homolog.
What is the protein family that this protein belongs to?
Belongs to the RNF181 family.
Protein: M2_I78AF
Sequence: MSLLTEVETHTRSGWECRCNDSSDPLVIAASIIGILHLILWIFDRLFFKCIYRRLKYGLKRGPSTEGVPESMREEYQQEKQSAVDVDDGHFVNIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: PSBJ_PEA
Sequence: MANTTGRIPLWIIGTVAGIVVIGLIGLFFYGSYSGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RNP1_METST
Sequence: MITPQNVFRHEFIGLNVEVINSKHEKFIGIKGIIIDETRNTIRVDTGKNEKLIPKSDVVFLFTLPQGEKVSIDGKVITARPEDRIKKKFTKIR
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 1, RNase P component 1, Rpp29.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMK_PSEPF
Sequence: MKIAVLSRNPRLYSTRRLVEAGTERGHEMVVIDTLRAYMNIASHKPQIHYRGKPLEGFDAVIPRIGASVTFYGCAVLRQFEMMGVFPLNESVAIARSRDKLRSLQLLSRRGIGLPVTGFAHSPDDIPDLIDMVNGAPLVIKVLEGTQGIGVVLCETATAAESVIEAFMGLKQNIMVQEYIKEAGGADIRCFVVGDKVIAAMKRQAKPGEFRSNLHRGGSASLIKITPEERMTALRAAKVMGLAVAGVDILRSNHGPLVMEVNSSPGLEGIETTTGKNVAGIIIEHLEKNGGPNMTRTKGKG
What are the official names of this protein?
Probable alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: GUAA_PSESM
Sequence: MALDIHAHRILILDFGSQYTQLIARRVREIGVYCELHPFDMDDEAIREFAPKGVILAGGPESVHEANSPRCPQAVFDLGVPVFGICYGMQTMAEQLGGKVAGSELREFGYARVDVVGKSRLLDGIEDHIDADGLFGLDVWMSHGDKVTKLPEDFHILASTPSCPIAGMADDARGYYGVQFHPEVTHTKQGGRILSRFILDICGCEALWTPSKIAEDAIAQVRAQVGTDSVLLGLSGGVDSSVVAALLHKAIGDQLTCVFVDNGLLRLHEGEQVMAMFAENMGVKVIRANAEEQFLNNLEGESDPEKKRKIIGRTFIDVFDAESCKLDNIKYLAQGTIYPDVIESAGAKSGKAHVIKSHHNVGGLPEEMNLKLVEPLRELFKDEVRRLGLELGLPYDMVYRHPFPGPGLGVRILGEVKKEYADILRRADHIFIEELRKADWYHKVSQAFVVFQPVKSVGVVGDGRRYAWVVALRAVETIDFMTARWAHLPYELLETVSGRIINEIEGISRVTYDVSSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: AMT3_DICDI
Sequence: MEQFSTSSSESSDSSSEYSLEFYMDTSWVLDAANLVFFMQAGFGMLEAGMVRAKNTKSILLKNLINTAICAISYYCVGHSFAYGKVNPNSFVGFGNFFLMDYTHYAYWMIQWAYAATATTIATGAMAERLQLHCYILFTLVQTILIYPFVAHWIWSQNGWLFDLGIVDFAGGAVIHIVAGITGACGSFLLGPRIGRFNQESGKPKNLPGHSVVLMSLGAMILWYSWYGYTAGASLGMTRSRVLPASRVSVVVTLSGATGLITVLGIGKIFNGHYDLVKGINGLIAGLVSSTSSCAYIEPWAAIIIGFIGGIVYWFSSWALLNWLRLDDPVDSTAIHLFGGCWSLISVAFFATHGRVRNPDIILPGGIFYGGGISLLWVQLVGMVLAILWAGFLSGIFFFTMDYFGKLRVDVDTELAGLDNSNHGGSAYIFD
What is the function of this protein?
Ammonium transporter that mediates the import of ammonium in prespore cells.  Controls ammonium homeostasis during growth and development.  Ammonium has been shown to function as a morphogen at multiple steps during the development.  May function as an ammonia sensor that relays information concerning ammonia concentrations to the signaling pathway involved in the slug versus culmination choice and regulates prestalk gene expression.
What are the official names of this protein?
Ammonium transporter 3.
What is the protein family that this protein belongs to?
Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, phagosome membrane; Multi-pass membrane protein.
Protein: CPN1A_SALSA
Sequence: MADLGVKAGDKVLLVWSQPSSPTTLKKLAESLGAMVGTDGRVSLENMERLIMSSHAASSYDWVLSSLLSDSFSVHTSETLAEMARVIKPDGKLVLEEPVTGTDDQKVRTAEKLISALKLSGLVSVTEVSKEPLTPEAVSALKTFTGFQGNTLSRVRMSASKPNFEVGSSSQLKFSFGKKTSKPVDKPALDPNAAKAWTLSANDMDDDDVDLVDSDALLDADDFKKPDAASLKAPSCGDGTTKKKKACKNCSCGLAEELEQESKGAKTISQPKSACGSCYLGDAFRCASCPYIGMPAFKPGEKIVLANTGLNDT
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2.  Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1.  NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.  Has anti-apoptotic effects in the cell.  Involved in negative control of cell death upon cytokine withdrawal.  Promotes development of hematopoietic cells.
What are the official names of this protein?
Anamorsin-A, Cytokine-induced apoptosis inhibitor 1-A, Fe-S cluster assembly protein DRE2 homolog A.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion intermembrane space.
Protein: NUJM_NEUCR
Sequence: MAPQGDDTVFQPKDAIKSGVSGALFSGGAGLLMASLRTSMKKNNVGSMHVFTHGGGTIISFTLAGGIYRFAQQASANLREKEDGWNHAIGAFLGGSVMGLRSLRFPVILGFGAMAGSVVGAFAFSGGLTGWGRDPNVDEFERKEAMRLNRRRPVEETLAEVGEGRGIYPPGYQERRRQRLLEKYGVEVKPVSADPNVASA
What is the function of this protein?
Transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase 21.3 kDa subunit.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: IDI2_LISW6
Sequence: MQKNDDLLRERRKDEHVALGVKQNEQLAPSSLDDIQLIGTSIPRYNVKDIDLTTTIFGVNVSLPFYINAMTGGSRHTKKINADLAEIAREVAIPMAVGSQSAALKNSSLMDTYQIVREVNPSGIIMANVSPEVAVQDGLRAIEMLEANALQIHINPAQELVMQEGDRSFSHWLARIEEYVKRSPVPIIVKEVGFGMTRETVKTLREVGVETVDLAGKGGTNFAQIENDRRRDQAYDFLLDWGISTGQSLIDMQHIDAPKIAYLASGGIRNPLDIVKSLALGADSVGMAGQIIYSLKKDGVSNTIEKLELWKEQLRGLFVLADAKNIAELKETSLIVNGKLAEWGNVRGIDLVQLANRK
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARND_ECO81
Sequence: MTKVGLRIDVDTFRGTREGVPRLLEILSKHNIQASIFFSVGPDNMGRHLWRLVKPQFLWKMLRSNAASLYGWDILLAGTAWPGKEIGHANADIIREAAKHHEVGLHAWDHHAWQAHSGNWDRQTMIDDIARGLRTLEEIIGQPVTCSAAAGWRADQQVIEAKEAFHLRYNSDCRGAMPFRPLLESGTPGTAQIPVTLPTWDEVIGRDVKAEDFNGWLLNRIQRDKGTPVYTIHAEVEGCAYQHNFVDLLKRAAQEGVTFCPLSELLSGTLPLGQVVRGNIAGREGWLGCQQMAGSH
What is the function of this protein?
Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
Protein: GUN_MAREN
Sequence: MPRMLAASAAIIATTLAPLSAQAAGCEMTLHGINLSGAEFGQPGDPYGQGYIYPSESTIKAFADDGFNAVRLPFLWERLQPTLNGTLDATELSRIKDTVETLRDNGMVVILDVHNYARYHGEMIGTPNVPVAAFADFWKRLSAVFANDDDVIFGLMNEPHDISAPAWLAAANAAIDAIRTIGAGNLVLVPGTAWTGAHSWSQTFYGPSNASVMAQVVDSSNNFAYEVHQYTDDDFSGKNADCSKIDDAVSALNDFTSWLNANDVQGFLGEFGTTEQIQCLRGLKQMVDVVQQNPRAWLGWAYWAGGDWWPKDSPMIIHSNPRDGGTQQLRTLQPVLGSNTTRASCNTKS
What is the function of this protein?
Shows highest activity on carboxymethyl cellulose (CMC).  Shows weak activity on xylan, and no activity against avicel, laminarin and chitin.
What are the official names of this protein?
Endoglucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
Protein: PNP_VEREI
Sequence: MGIFNKVTKTFQWGDQTVVMETGEIARQASGAVLVSIDDTVVLATVVASRSIKPGQDFFPLTVDYIEKTYAAGKIPGSFFKREAKPSEHETLTSRLIDRPLRPLFPQGFFNEVHLVIHTLSLNPEVDADIAALIASSAALALSGIPFNGPIGAARVGYIQGEYRLNPGPTARKSSQLDLVVAGTEAAVLMVESEAQQLSEEIMLGAVVFGHQQGKVAIDAIHELVHAAGKPVWQWEAPARDEALIARVAALADDKLRAAYQIRNKQARTEACRAAYAAVLAQLQADGVECDTVKAEGLLFDIEAGIVRSQILAGEPRIDGRDTRTVRPIEIRAGVLPRAHGSALFTRGETQALAVATLGTERDAQRIDALAGEYDDRFMLHYNMPPFATGEVGRMGSTKRREIGHGRLAKRALVAVLPTKEEFPYTMRVVSEITESNGSSSMASVCGGCLSLMDAGVPMKAHVAGIAMGLIKDGNRFAVLTDILGDEDHLGDMDFKVAGTTAGITALQMDIKIQGITREIMQVALAQAKEARMHILGKMQQAIGQAKTEVSNFAPKLYTMKINAEKIRDVIGKGGAVIRALTEETGCQINIEEDGTITIAATDAAKADIAKRRIEQITAEIEIGKIYEGPVTKLLDFGALINLLPGKDGLLHISQIAHERVERVSDYLSEGQIVRVKVMEADERGRVKLSMKVLAERPAPGSDRFGTGSERPAPGSDRPALAEREPRREMRDHGHPPSEQQQQQSPPADTGSGQRVG
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.