PharMolix/UniProtQA huggingface dataset:
Protein: DPP3_DICDI
Sequence: MSVPSSVIENHLVPKEIPVYRLNARESFNLLTEKEQLYAHHISVACWWGSKICLGQTSIESGPIFNLFQNLFSIQNLKSTVVPNIVSEEEYSDLLSYAATFYGNMGNYLSFGDSKFIPRISKEKLQLIINKVNDNKVNEYWGKCSELMYSLDKQVRELGIDGNGISTYYSPNITKVEIEKVQKFMDSKSISPYNTRLFKVSENNYNLLIASASTSTPTVSHQFDGYTINIVYGDWNKNLTKVVDNLKLALPYAANENQTNMLKKYIDSFYSGSIDDHKDSQRWWIKDISPAVETNIGFIESYRDPYGVRGEWEGFVSMVNKEMSLKFGKLTDNATTFLSKLPWDKSFEKEKFNKPDFTSLEVLTFATTGIPAGINLSNYDDIRQTEGFKNVSLGNVIAARKDEYVTFIQESDQKLFNELSTEAFELQVGIHELYGHGSGKLFTTDANGNVNFKVGEVINPLTNKPIDPKTEVYKFGETYDSVFKSLGSPMEECRAECCGIYLSPDEKILELFGFTDPKKAEDVYYVNWLIMARAGVCALEFYSPPSEGAPGKWRQAHMQARYCILTTFLRSGIVTLDKTADDVIVKLDKSKIRGIGVKAVGDFLNRLMVYKATANIDASIKLFDEYTHVNEEFLAIRDIVLAKKKPRKVFVQAHTYLNSNGKVCLQDFDDSTQGMIDSMITRFGKDDSDML
What are the official names of this protein?
Dipeptidyl peptidase 3, Dipeptidyl aminopeptidase III, Dipeptidyl arylamidase III, Dipeptidyl peptidase III, DPP III.
What is the protein family that this protein belongs to?
Belongs to the peptidase M49 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_GEOSE
Sequence: MITKVDRNAVRKKRHARIRKKIFGTTERPRLSVFRSNKHIYAQIIDDTKSATIVSASTLDKEFGLDSTNNIEAAKKVGELVAKRALEKGIKQVVFDRGGYLYHGRVKALADAAREAGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18, BL22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RPOB_ANAMF
Sequence: MSSAGGSSGPGYVLNDFDAVPRLSYAKSIDIRDSLTDLIRIQRDSYDAFIGIDRDGSSGIQSIFEAMFPIRDLLGRAVLEFVGYNIGEPQYDEYECIKRGITFSVPIRITLRFVVWKVQEVSFKEVKYVVDEDTSERSVKYMKEQEVSIGDLPMMTSYGTFIINGIERVIVSQMHRSPGVFFDSDKGKTYSSGKLIYSARVIPYRGSWLDFEFDIKDIIYFRIDKKRKLPVSYLLKALGMSNNDILDAFYDKVIYTRCDKGWRVPFIVDRFKGVRLSYDLMDVDGSVLVKANTRITLRIAKKLYADGLREYMVPFSGITGMFVAADLVDPSSGAVIVSAGETITSEHIVKLELFDISEIAFLNIDFLTVGPYVLNTLFLDKNMTQEDALFEIYRVLRSGESPNLDAVKSFFKGLFFESERYDLSVVGRIKLNSHLGLDVDENTTVLTKEDIVQVVKKLVLLRDGEGVVDDIDHLGNRRVRSVGEFIENQFRIGILRLERMIMDYMSSVNFDNAMPCDFVNPKVLATVLKDFFSSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGQNIGLISSLAIYAKINKYGFIESPYRKVENRVVTDKVEYLLAMQEGDYYIADAGAAIDENNRFVDDMLYCRHGGNFVMVKSEDVDYVDVSPKQIVSVAASLIPFLENNDANRALMGSNMQRQAVPLLKSEAPLVGTGMEFVVAAGSGAVVLAKRDGIVHRVDGSYIVIRAFDANKDECLGVDIYRLRKFQRSNHNTCINQRPVVKLGDYVKANDVIADGSAIDRGELALGKNVLVAFMSWQGYNFEDSIVISSDVVKRDVFTSIHIEEFECVVRDTPLGPEKIMRSVPDVNEESLSHLDDVGIVNIGAEVSASSILVGKVTPRPPVSLPPETKLLVTIFGEKVFDCVDSSLYLPPDVEGTVIDVHVFVRRGVEENDRSLLIKQSEISSFVKERDYEIDVVSEYFHDELRKLLRNAGVKVKGYSDLDSFFAEASDDTLWSTGLADAKVAAKVKDMRERFDSIVGEAHRKFEQKVDKLNYGYDLPQGVLTIVKVFVAVKHNLQPGDKMAGRHGNKGVISRIVPAEDMPHLEDGTPVDIILNSLGVPSRMNIGQILETHLGWAAVNLGKKIGRILDKGGPSMIADLRDFLDKIYDGQKLKSDIASMSSEALLVFANRLRKGVPMAAPVFEGPKDAQISKLLELAEVDPSGQVYLYDGRLGKKFDRKITVGYIYMLKLHHLVDDKIHARSVGPYGLVTQQPLGGKSHFGGQRFGEMECWALQAYGAAYTLQEMLTVKSDDIVGRVKIYESIIKGDSNFECGIPESFNVMVKELRSLCLNVVLKQDKEFTSGEVE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: PDXA_ECO57
Sequence: MVKTQRVVITPGEPAGIGPDLVVQLAQREWPVELVVCADATLLTDRAAMLGLPLTLRPYSPNSPAQPQTTGTLTLLPVALRESVTAGQLAIENGHYVVETLARACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRVALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHMGTEEIDTIIPVLDELRAQGMKLNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGRGEADVGSFITALNLAIKMIVNTQ
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2550_ORYSI
Sequence: MAQNKTIAVALLLATLVAVMGKEPETLEETLRAGCKEECSEQKKKAPIDEKQCEDFCFIKTKSIFEAHKGVKDLKADRFIDFCNNECNAVYKEDPATSKKCAESCEADAKEAEVFLDKVVAYMQTMKQA
What are the official names of this protein?
Uncharacterized protein OsI_009113, Unknown protein AN04 from 2D-PAGE of anther.
Protein: PMPI_CHLMU
Sequence: MRPDHVNLCCLCATILSPTAILFGQDALDKSALITKNPNSIVCTFLEDCTMENFSPALLSHARQDDPLYIIGNTHNWFVSNLHPSTNEERFLKEKGDLSIQDFRFLSFTDCSSSTEDSPSILYHKNGQLFLRNNGNMSFYRNHSEGSGGALSTDALFLQHNYLFTNFEENSSAKNGGAIQAQTLSLSRNVSSLSFSRNRANLNGGAICCQNLICSGNVNPLFFTNNSALNGGAICCINEQNLSEKGCLSLAYNQETLFSGNSAKEKGGAIYTKHMVLRHNGPVSFVNNSAKLGGAIAIQSGGSLSIIAGGGSVLFQNNSCHFSDQGTVRNAIYLEKNALLSSLEARHGDILFFDPIVQEVVSPEFSTTSALTPLRIQTNTNRAVIFSSENLSKEEKTEANLISKIQQPIELQSGCLVLKDRVILSAPSLSQAPQALLVMDVGTSLTTSSDLKLTTLSIPLHSIDTENSVSIQSPTLSIQKIFLSNSEHENFYENVELLSKDQKDIPLLSLPKGLPHPDLPDGNLSSHFGYQGDWNFSWQTSDQRETLVANWTANSYIPHPERQSALVANTLWNTYSDMQAVQSMINTTAQGGAYLFGTWGSAVSNLFYSHGNSGKSTDNWKHRSLGYLFGISTHSLDDHSFCLAAGQLFGKSSDSFVTSADTTSYIAAIQTQIATSLIKISAQACYNESIHELKTKYRSFSKEGFGAWHSVAVSGEIGASIPIVSNGSGLFSSFSIFSKLQGFSGKQDGFEESRGEARAFADSSFTNISLPVGIAFEKKSQKTRNYYHFLGAYIQDLKRCVESGPVTLLKNSVTWDAPMANLDSRAWMFRLTNQRALHRFQTLVNMSYMLRGQSYSYSLDLGTTYRF
What are the official names of this protein?
Probable outer membrane protein PmpI, Polymorphic membrane protein I.
What is the protein family that this protein belongs to?
Belongs to the PMP outer membrane protein family.
What are the subcellular locations of this protein?
Secreted, cell wall. Cell outer membrane; Peripheral membrane protein; Extracellular side.
Protein: NADK_BLOFL
Sequence: MTSSIFRTIGIIGHSSYPKAINTYDVLYRWLYNKGIKVMIEQHASHLLRTHKAIIGNLHDIGDYADLAIVIGGDGNMLRAANVLSQYDIKIIGINLGNLGFLTDLNPHSALIELSKILSGHFINEKRFLLDIKIQHYNNVTILGTAINEVILYTNTIKNMIKFELYINNNFTFSSRSDGLIIATPTGSTAYALSAGGPILSPSVEGIVLVPICPHTVSSRPIIIDNKSTISLKFPKITPKLTIRCDNQNPIYIDKEKEIFIQRSNHILDLIHPNNYNYFKNLRIKLGWQKNSI
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHN_PROM1
Sequence: MPLLLSGQKFRTDLESFGCLAILSPLEGGAETRLLRRLRASGYQTQITSARGLGDPVVFLTQLHGIRPPHLGHQNVGRNGALGEVQQVIPQLNELLVEDKPLVLWLLEGQVLSKSELLAISNLCQKEPRIKIVIEMGGARSIKWQPLNEFINKD
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit N, NAD(P)H dehydrogenase I subunit N, NDH-1 subunit N, NDH-N.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhN subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SYH_VIBCM
Sequence: MAKTIQAIRGMNDCLPTQSPLWQKVEGVVKNVISAYGYSEVRMPIVEMTHLFSRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRSGIENGLLYNQEQRLWYMGPMFRHERPQKGRYRQFHQCGVEVFGLDGPDVDAELIMMTARLWRELGIAQHVRLELNSIGSLEARANYRTALIDYLEQYQNVLDEDCKRRMYTNPLRVLDSKNPDVQAILGDAPQLSDYLDAESKQHFAGLCELLDAAGIEYTVNQRLVRGLDYYNRTVFEWITESLGSQGTVCGGGRYDGLVEQLGGKPTPAVGFAMGLERLVLMMETLGNTDVRRSVDVYMVTAGEGTMMAGMKLAEQLREQVPGLRVMTHFGGGNFKKQFKRADKVGAAIALVLGEDEVAAQTVVVKDLAGGEQNTVAQAEVAKLLAHLA
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AEPE_BPA50
Sequence: MALTEAWLIEKANRKLNAGGMYKITSDKTRNVIKKMAKEGIYLCVAQGYRSTAEQNALYAQGRTKPGAIVTNAKGGQSNHNYGVAVDLCLYTNDGKDVIWESTTSRWKKVVAAMKAEGFKWGGDWKSFKDYPHFELCDAVSGEKIPAATQNTNTNSNRYEGKVIDSAPLLPKMDFKSSPFRMYKVGTEFLVYDHNQYWYKTYIDDKLYYMYKSFCDVVAKKDAKGRIKVRIKSAKDLRIPVWNNIKLNSGKIKWYAPNVKLAWYNYRRGYLELWYPNDGWYYTAEYFLK
What is the function of this protein?
Cell wall lytic enzyme.  Hydrolyzes the link between L-alanine and D-glutamate residues in certain bacterial cell-wall glycopeptides.
What are the official names of this protein?
L-alanyl-D-glutamate peptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M15C family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS2_XYLFT
Sequence: MCNEPATSDVALPDLDWAKGDGLLPVIVQDADTLRVLMLGYMNSQALEVTQRSRLVTFYSRSKQRLWTKGERSGHVLHLVAIDADCDADTLLVQARPRGPTCHLGRTSCFPAAPGQFLGALDALVAERERERPQDSYTTALFEQGVRRIAQKVGEEGVETALAGVVQADDALLDESADLLYHLIVLLRARGLSLADAVTVLEARHR
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisIE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_RICPR
Sequence: MKKILGIESSCDDTAISIITERRKILSNIIISQNTEHAVFGGVVPEIAARSHLSNLDQALKNVLKKSNTELTEISAIAATSGPGLIGGVIVGSMFARSLSSALKKPFIAINHLEGHALTARLTDNISYPYLLLLASGGHCQFVAVLGLGKYKILGTTIDDAVGETFDKVAKMLNLSFPGGPEIEKRAKLGNPHKYKFPKPIINSGNCNMSFSGLKTAVRTLIMNLKEVNDSVINDIAASFQFTIGAILSSKMQDAIRLYKQILNDYYEDINHPTKLNLKSFRKDEFNWKPLECITRPKYRIHIQNSYRSNLLNDTIVIAGGVAANKYLQEILSDCTRPYGYRLIAPPMHLCTDNAAMIAYAGLERYNNKLFSPLDFCPKAKWSLEDI
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX1_HAEIN
Sequence: MVKDFSFFIYDYESFGVNPATDRPAQFAGIRTDADFNIIGEPIMFYCKQTNDYLPAPEAVMVTGITPQECNEKGLSEPEFAANILAEFSQPNTCVMGYNNIRYDDEMTRYTFYRNFIEPYEYSWKNGNSRWDLLDLVRACYALRPEGINWAYDDDGMPSFRLEKLTKANSIEHENAHDAMADVYATIAMAKLIKEKQPKLFQYFFENRGKKEIEKLVDTGAMTPLVHVSGMLGNYRGNCTWVAPLAWHPTNQNALIVCDLTGDIDNLLAKSADELRADLYTKKLELEERGVSSVPLKLVHINKCPILAPAKTLLPETANRLGIDRQLCLDNLAKLRASFDIREKVADIFNEERQFASNDNVETELYNGFFSNADKNNMAILRSLPAEKLSEHGLAFEDKRILELLFHYRARHFYKTLTRAEQIKWKKYRQNKLEKSAVEFEASLQRLVEXHSDNSEKLSLLQQVYEYGIKLLG
What is the function of this protein?
Degrades single-stranded DNA (ssDNA) in a highly processive manner.  Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties following the cleavage of DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease or AP lyase.
What are the official names of this protein?
Exodeoxyribonuclease I, ExoI, Exonuclease I, DNA deoxyribophosphodiesterase, dRPase.
Protein: SIPC_SALT1
Sequence: MLISNVGINPAAYLNNHSVENSSQTASQSVSAKDILNSIGISSSKVSDLGLSPTLSAPAPGVLTQTPGTITSFLKASIQNTDMNQDLNALANNVTTKANEVVQTQLREQQAEVGKFFDISGMSSSAVALLAAANTLMLTLNQADSKLSGKLSLVSFDAAKTTASSMMREGMNALSGSISQSALQLGITGVGAKLEYKGLQNERGALKHNAAKIDKLTTESHSIKNVLNGQNSVKLGAEGVDSLKSLNMKKTGTDATKNLNDATLKSNAGTSATESLGIKDSNKQISPEHQAILSKRLESVESDIRLEQNTMDMTRIDARKMQMTGDLIMKNSVTVGGIAGASGQYAATQERSEQQISQVNNRVASTASDEARESSRKSTSLIQEMLKTMESINQSKASALAAIAGNIRA
What is the function of this protein?
Actin-binding protein that interferes with host cell actin cytoskeleton.  Nucleates actin polymerization and condensates actin filaments into cables (bundling).  SipA potenciates SipC activity and both are required for an efficient bacterial internalization by the host cell (By similarity).
What are the official names of this protein?
Cell invasion protein SipC, Effector protein SipC.
What is the protein family that this protein belongs to?
Belongs to the invasin protein C family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the type III secretion system 1 (SPI-1 TTSS) and inserted into the host cell plasma membrane.
Protein: RLMH_SALPB
Sequence: MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRGKNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLANELERWKQDGRDVSLLIGGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_HAHCH
Sequence: MENLEGIVDRAKDAVAKAESEQSLEQLRVDYLGKKGRITQLLKELGRLDAAERPAAGAKINEAKLLVQDLINEAKSELSSKNEAAKLAAESIDVTLPGRKESLGTLHPVTRTMLRIEDFFARSGYTVEEGPEIQDDYHNFEALNIPSHHPARAMHDTFYFDPKTLLRTHTSPVQIRVMESSKPPFRMICPGRVYRCDSDMTHTPMFHQVEGLMVDKHVSFADLKSTIVEFLREFFEKDLEVRFRPSYFPFTEPSAEVDIEWGRNEDGSIKWLEVMGCGMVHPKVFEAAGVDSETYSGFAFGMGVERLAMLRYGVNDLRMFFENDMRFLDQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7S_HELMI
Sequence: MAKGKANLNLTYEAAIGRLEEVVRSLETGEASLDESLKLFQEGIGLVRHCHSQLDAYEAKVQRLIETPDGAAVVEERRTEEGE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_ECO55
Sequence: MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYAEEGADELVFYDITASSDGRVVDKSWVSRVAEVIDIPFCVAGGIKSLEDAAKILSFGADKISINSPALADPTLITRLADRFGVQCIVVGIDTWYDGETGKYHVNQYTGDESRTRVTQWETLDWVQEVQKRGAGEIVLNMMNQDGVRNGYDLEQLKKVREVCHVPLIASGGAGTMEHFLEAFRDADVDGALAASVFHKQIINIGELKAYLATQGVEIRIC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_CALBD
Sequence: MIEKLQVIEEKYLELEKKISDPEIISQPQEWQKLMKEHSNLQPIVEKFREYKRILDTIKEAEELLDTDLDEDFEKLVKEELNRAKEQKEIVETQLKILLLPKDPNDEKNVIMEIRAGAGGEEAALFAAELFRMYSRYAERKNWKVEVMSTSESDLDGFKEVIFMISGKGAYSRLKYESGVHRVQRVPVTESGGRIHTSTATVAVLPEVEDVEVEIREEDLEIDTFRAGGAGGQHVNKTESAVRIVHKPTGIVVTCQDERSQHANRDRAMKILRARLYDYYQSIQQKEIESQRRSQVGTGDRSERIRTYNFPQGRVTDHRIGLTLYKLEQILDGELDEIIDALITHFQTERLKEIG
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_ECO7I
Sequence: MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTSRLLWWPLLRGVILPLRSPRVAKLYASVWMEGGSPLMVYSRQQQQALAQRLPETPVALGMSYGSPSLESAVDELLAEHVDHIVVLPLYPQFSCSTVGAVWDELARILARKRSIPGISFIRDYADNHDYINALANSVRASFAKHGEPDLLLLSYHGIPQRYADEGDDYPQRCRTTTRELASALGMAPEKVMMTFQSRFGREPWLMPYTDETLKMLGEKGVGHIQVMCPGFAADCLETLEEIAEQNREVFLGAGGKKYEYIPALNATPEHIEMMANLVAAYR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_BACP2
Sequence: MDTIAAISTPMGEGAIAIIRLSGPEAVQIADRMYKGPKEKKLVSVDSHTIHYGHIVDARTDQVIEEVMVSVLRAPKTFTREDVIEINCHGGIVTVNKVLQLALREGARLAEPGEFTKRAFLNGRIDLSQAEAVMDLIRAKTDRAMNVAITQMEGRLSGLVQRLRGEILETLAHIEVNIDYPEYDDVEEMTHRVLVEKATSVKKEIESLLSTSHQGKILREGLSTVIIGRPNVGKSSLLNSLVQETKAIVTDIPGTTRDVIEEYVNVRGVPLRLVDTAGIRETEDIVERIGVERSRQVLKEADLILLVLNYSEELSEEDIKLFEAVSGMDIIVIVNKTDLEPKLDVEKVKQLAKDRPVVTTSLLQEKGIDELEMAIQSLFFTGSIESGDLTYVSNTRHIALLQAAKQSIEDALEGIEMDVPIDIVQIDLTRCWEQLGEIIGDAVHESLIDQLFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS2_BUCBP
Sequence: MLKKINFIDINWNKVDNMLPVVIQHNLSGKVLMHGYMNQEALKRTQNEGIVTFYSRTKQRLWTKGETSKNFLYVTDIRLDCDQDALLIFVRPVGKTCHLNHVSCFQVPSENLFFLHDLDCMLKFKKHYGLENSYTFNLHKNGVNRIAQKVAEEAIETAISAVSKNKVELINESSDLVYHLLVLLHSYDLDLYDVIKNLKMRSNKQV
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisIE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KI2S4_HUMAN
Sequence: MSLMVIIMACVGFFLLQGAWPQEGVHRKPSFLALPGHLVKSEETVILQCWSDVMFEHFLLHREGKFNNTLHLIGEHHDGVSKANFSIGPMMPVLAGTYRCYGSVPHSPYQLSAPSDPLDMVIIGLYEKPSLSAQPGPTVQAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAVRSINGTFQADFPLGPATHGGTYRCFGSFRDAPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHVLIGTSVVKIPFTILLFFLLHRWCSDKKNAAVMDQEPAGNRTVNSEDSDEQDHQEVSYA
What is the function of this protein?
Receptor on natural killer (NK) cells for HLA-C alleles.  Does not inhibit the activity of NK cells.
What are the official names of this protein?
Killer cell immunoglobulin-like receptor 2DS4, CD158 antigen-like family member I, Natural killer-associated transcript 8, NKAT-8, P58 natural killer cell receptor clones CL-39/CL-17, p58 NK receptor CL-39/CL-17.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PK3C3_MOUSE
Sequence: MGEAEKFHYIYSCDLDINVQLKIGSLEGKREQKSYKAVLEDPMLKFSGLYQETCSDLYVTCQVFAEGKPLALPVRTSYKAFSTRWNWNEWLKLPVKYPDLPRNAQVALTIWDVYGPGSAVPVGGTTVSLFGKYGMFRQGMHDLKVWPNVEADGSEPTRTPGRTSSTLSEDQMSRLAKLTKAHRQGHMVKVDWLDRLTFREIEMINESEKRSSNFMYLMVEFRCVKCDDKEYGIVYYEKDGDESSPILTSFELVKVPDPQMSMENLVESKHHKLARSLRSGPSDHDLKPNATTRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYLLQLVQALKYENFDDIKNGLEPTKKDSQTSASESLSNSGVSSGDIDSSQIITNPLPPVASPPPASKAKEVSDGENLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEMYLNVMRRFSQALLKGDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNEKMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDGGKYPVIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLDTEGSIQNFFRKYAPSETGPYGISAEVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHALFAAVVEQIHKFAQYWRK
What is the function of this protein?
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis.  As part of PI3KC3-C1, promotes endoplasmic reticulum membrane curvature formation prior to vesicle budding.  Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2.  Involved in the transport of lysosomal enzyme precursors to lysosomes.  Required for transport from early to late endosomes (By similarity).
What are the official names of this protein?
Phosphatidylinositol 3-kinase catalytic subunit type 3, PI3-kinase type 3, PI3K type 3, PtdIns-3-kinase type 3, Phosphoinositide-3-kinase class 3.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family.
What are the subcellular locations of this protein?
Midbody. Late endosome. Cytoplasmic vesicle, autophagosome. Note=As component of the PI3K complex I localized to pre-autophagosome structures. As component of the PI3K complex II localized predominantly to endosomes (By similarity). Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme (PubMed:24089209).
Protein: GLGB2_CLOPE
Sequence: MGGKEMRNCKELKHEKNGNVTEKVGKNKGKSKKVSKDESLLSFDLFLEGKEHSAYKFMGAHFITENRKRGVRFTTWAPRASKIYVIGDFNNWELKEEYSMKKINERGIWSLFLPKLEEGIKYKFAVVNECGNNTVYKADPYAFKSELRPNTASVLTKIKSFRWGDKRWLNKREKEGLDNKPMNIYELHLGSWKRKDGEFMTYEEISEVLVEYIKEMGYTHVEFMPINEHPLDASWGYQGVGYYSVTSRYGDLNGLKTLINKLHKNNIGVLLDWVPSHFCKDEHGLFMFDGSPTYEYEAWWKANNEGWGTCNFDLGRPEVKSFLFSNAMYWINEFHVDGLRVDAVSNMLYLDYGREYGEWEPNIYGGNGNLEAIAFLKELNTIIKKEGKGAITVAEESTSWEGITKPVEEDGLGFDYKWNMGWMNDTLSYIELDPIYRKYHHNKMNFSMMYNYSEKFILPISHDEVVHGKKSLINKMWGDDWKKYAGLRVYASFMMGHPGKKLMFMGCEFGQFVEWREWEELQWNVIEEFDIHRKTKEYFKALNKFYLENSSLWSLDYEEEGFKWIDADNSEESVLSFIRIGKNKKEKLIFICNFTPEVYYDFKVGVPELGEYVEAFNSDALEFGGAGNIVGDSILKATEESFKDFDYSISVKVPPLGTLVLKVK
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB 2, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase 2, Alpha-(1->4)-glucan branching enzyme 2, Glycogen branching enzyme 2, BE 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: RBFA_PSEPW
Sequence: MAKEYSRTQRIGDQMQRELAELIRREVKDPRVGLVTITAVDVSRDLGHAKVFITVMGEETPDAVQQSLKALNSAASFLRLHLGRSMQLRSVPQLHFHFDESVSRGVHLSALIERAVAEDRLHKDTDEQDTKE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.