PharMolix/UniProtQA huggingface dataset:
Protein: MTCL1_HUMAN
Sequence: METLNGPAGGGAPDAKLQPPGQHHRHHHLHPVAERRRLHRAPSPARPFLKDLHARPAAPGPAVPSSGRAPAPAAPRSPNLAGKAPPSPGSLAAPGRLSRRSGGVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPLSRAGKPPGAEPPSAAAKGRKAKRGSRAPPARTVGPPTPAARIPAVTLAVTSVAGSPARCSRISHTDSSSDLSDCPSEPLSDEQRLLPAASSDAESGTGSSDREPPRGAPTPSPAARGAPPGSPEPPALLAAPLAAGACPGGRSIPSGVSGGFAGPGVAEDVRGRSPPERPVPGTPKEPSLGEQSRLVPAAEEEELLREMEELRSENDYLKDELDELRAEMEEMRDSYLEEDVYQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGELIRSLEQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKTFNQDDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPPSTREAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQEREGPGRDHAPSIPTSPFGDSLESSTELRRHLQFVEEEAELLRRSISEIEDHNRQLTHELSKFKFEPPREPGWLGEGASPGAGGGAPLQEELKSARLQISELSGKVLKLQHENHALLSNIQRCDLAAHLGLRAPSPRDSDAESDAGKKESDGEESRLPQPKREGPVGGESDSEEMFEKTSGFGSGKPSEASEPCPTELLKAREDSEYLVTLKHEAQRLERTVERLITDTDSFLHDAGLRGGAPLPGPGLQGEEEQGEGDQQEPQLLGTINAKMKAFKKELQAFLEQVNRIGDGLSPLPHLTESSSFLSTVTSVSRDSPIGNLGKELGPDLQSRLKEQLEWQLGPARGDERESLRLRAARELHRRADGDTGSHGLGGQTCFSLEMEEEHLYALRWKELEMHSLALQNTLHERTWSDEKNLMQQELRSLKQNIFLFYVKLRWLLKHWRQGKQMEEEGEEFTEGEHPETLSRLGELGVQGGHQADGPDHDSDRGCGFPVGEHSPHSRVQIGDHSLRLQTADRGQPHKQVVENQQLFSAFKALLEDFRAELREDERARLRLQQQYASDKAAWDVEWAVLKCRLEQLEEKTENKLGELGSSAESKGALKKEREVHQKLLADSHSLVMDLRWQIHHSEKNWNREKVELLDRLDRDRQEWERQKKEFLWRIEQLQKENSPRRGGSFLCDQKDGNVRPFPHQGSLRMPRPVAMWPCADADSIPFEDRPLSKLKESDRCSASENLYLDALSLDDEPEEPPAHRPEREFRNRLPEEEENHKGNLQRAVSVSSMSEFQRLMDISPFLPEKGLPSTSSKEDVTPPLSPDDLKYIEEFNKSWDYTPNRGHNGGGPDLWADRTEVGRAGHEDSTEPFPDSSWYLTTSVTMTTDTMTSPEHCQKQPLRSHVLTEQSGLRVLHSPPAVRRVDSITAAGGEGPFPTSRARGSPGDTKGGPPEPMLSRWPCTSPRHSRDYVEGARRPLDSPLCTSLGFASPLHSLEMSKNLSDDMKEVAFSVRNAICSGPGELQVKDMACQTNGSRTMGTQTVQTISVGLQTEALRGSGVTSSPHKCLTPKAGGGATPVSSPSRSLRSRQVAPAIEKVQAKFERTCCSPKYGSPKLQRKPLPKADQPNNRTSPGMAQKGYSESAWARSTTTRESPVHTTINDGLSSLFNIIDHSPVVQDPFQKGLRAGSRSRSAEPRPELGPGQETGTNSRGRSPSPIGVGSEMCREEGGEGTPVKQDLSAPPGYTLTENVARILNKKLLEHALKEERRQAAHGPPGLHSDSHSLGDTAEPGPMENQTVLLTAPWGL
What is the function of this protein?
Microtubule-associated factor involved in the late phase of epithelial polarization and microtubule dynamics regulation.  Plays a role in the development and maintenance of non-centrosomal microtubule bundles at the lateral membrane in polarized epithelial cells.
What are the official names of this protein?
Microtubule cross-linking factor 1, Coiled-coil domain-containing protein 165, PAR-1-interacting protein, SOGA family member 2.
What is the protein family that this protein belongs to?
Belongs to the SOGA family.
What are the subcellular locations of this protein?
Lateral cell membrane. Apical cell membrane. Cytoplasm, cytoskeleton, spindle pole. Midbody. Cytoplasm, cytoskeleton. Note=Colocalized with microtubules at the base of cilia. Gradually accumulates on the apicobasal microtubule bundles during epithelial cell polarization (By similarity). Colocalized with the apicobasal microtubule bundles running beneath the lateral membrane. Colocalized with microtubule bundles in the spindle pole in mitotic cells and in the midbodies at the end of cytokinesis.
Protein: TATA_XYLFT
Sequence: MGSFSLLHWLVVLVIVLLVFGTKRLANGAKDIGSAIKEFKKSLHEDDKPTDQLGSTSQSTASGPQQDHGKH
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RS8_HELPH
Sequence: MVNDIIADSLTRLRNASMRRLEFTQLYYAKIVVSILEIFKEKGFIKDFNVKDKDKKQSVYVQLAYDEKGHSKISEVKRLSKPGRRVYKQKNELKRFKNGYGVIVVSTSKGVITNEEAYRQNVGGEVLCSIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: DGTL1_SHEWM
Sequence: MIASPWHERRLNEDKKRRNDHRSPFQRDRARILHSAAFRRLQAKTQVLGVGMNDFYRTRLTHSLEVSQIGTGIRAQLKLKQPQHLPLFDSMSLIESLCLAHDIGHPPFGHGGEVALNYMMRNHGGFEGNGQTFRILTGLEPYTECFGMNLCRRTLLGVLKYPGLYSSLHHNSQQAEVNNIRQLKPADWPPVKGVFDDDKAILDWVLAPLIDSDRERFLQTHTAATGKHKRTRYKSLDCSIMELADDIAYAVHDLEDAIVMGIVSSFQWHSDVTETLKNSKDSWIREEFATIGDKLFSHHHHQRKDAIGTLVNGFVTAIDLKEDLAFTEPLLRFNAALDDEFDSALEVLKQFVYKFVIRKPEIQMLEYKGQQTVMELFEAFESDPERLLPTHTQERWRESHNKGLNCHRVIADYISGMTDEFAARLHQQLFSPKLGSMIELSHEL
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: HYPA_TRIEI
Sequence: MHELGITQNIVAIVAENANNRLIKRVTLEIGELSAIMPNAIEFCFDVCTQGTVLEGATLEIIKIPGLGKCRQCATEIPLEQPFGICHVCNSVELDIIQGQELKIKEMEVEELSV
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: NS1_I56A1
Sequence: MDSNTVSSFQVDCFLWHIRKRFADQELGDAPFLDRLRRDQKSLRGRGSTLGLDIETATRAGKQIVERILEEESDEALKMTIASVPASRYLTDMTLEEMSRDWFMLMPKQKMAGSLCIRMDQAIMDKNIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTDEDVKNAIGVIIGGLEWNDNTVRVSETLQRFA
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: Y578_RHOCS
Sequence: MLTSDRLRGMLRRLPGRLPDAVGVVRHAVPRFWNNNGFAIAASLTYTTLLALVPLLTVTFAIFSAFPAYGRLRDTARELIFDSLAPSVSDEVQAYFDQFISNAAALTGFGVIGLSLTSILLFFSVEAALNVIFRATEPRPLVIRLLSFWAVLTIMPLLLGASLSVTSGVVADLQATGRDAVTVLRFMLPGLLEAAAFTLMFLMIPNREVQWFDALVGGIAAALLMEVSKVGFGLYIAAFPTYETIYGALSVIPIFLFWLYTVWSVVLFGAEITATLPEWRAGKITQVGPEGLLSAQRIVVAVAILHELQRAARLGVGIRRGTLSTRVPVGANVIDGMLEQLQAAHWVARTRDGAWVATRNLSDATVDDLRHSLGMAIRGNLRSVGHLSAGWQNRLADLFERAEAADREVLGVCFADLFADPPSGQPSGQVETAVRQRTGLQGRI
What are the official names of this protein?
UPF0761 membrane protein RC1_0578.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RLMN_METS4
Sequence: MATASLDTARPERRAGSDPFIEKTPEVRPEAMVATGRPSLVGLTRGALRERLAAIGVPEREQRMRTGQLWHWINVRGAASFEAMTNVGKGLKAQLEEAYTLDRPEVVSEQVSRDGTRKWLLRMPPTGRHDHNRGAEIECVYIPANDRGTLCVSSQVGCTLTCSFCHTGTQRLVRNLSAQEITAQLVVARDRLGDWPGQVPPKGTFVPVDGSRFVSNIVFMGMGEPLYNVDNVVDAVGVMSDNEGLGLSRRRITVSTSGVVPQFERLGIDANAMLAISLHAVRDDLRDELVPLNRKYPIRTLLEACRNYPGVSNARRITFEYVMLKGVNDSDSEARELVRLLKGIPAKINLIPFNPWPGSRYECSDWERIERFSEIVFNAGYASPVRTPRGRDILAACGQLKSETEKLRARARLMLEDGIGAEGVYGAVDDD
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1152_STAAR
Sequence: MSEIKRLEINYKTDELFENFRAFGNKDLYMVNELNGQMIDASSDSPFYGIFVGDQLGARMALLKKGDVEEIYFPDFEDYILLWKLEVLPKYQNRGYASELIDFAKSFNMPIKAIGRNDSKDFFLHHGFTDVEAKNIEGHDVLLWKP
What are the official names of this protein?
Uncharacterized N-acetyltransferase SAR1152.
Protein: Y1529_STAAN
Sequence: MKLSFHGQSTIYLEGNNKKVIVDPFISNNPKCDLNIETVQVDYIVLTHGHFDHFGDVVELAKKTGATVIGSAEMADYLSSYHGVENVHGMNIGGKANFDFGSVKFVQAFHSSSFTHENGIPVYLGMPMGIVFEVEGKTIYHTGDTGLFSDMSLIAKRHPVDVCFVPIGDNFTMGIDDASYAINEFIKPKISVPIHYDTFPLIEQDPQQFKDAVNVGDVQILKPGESVQF
What are the official names of this protein?
UPF0173 metal-dependent hydrolase SA1529.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: KCMF1_MOUSE
Sequence: MSRHEGVSCDACLKGNFRGRRYKCLICYDYDLCASCYESGATTTRHTTDHPMQCILTRVDFDLYYGGEAFSVEQPQSFTCPYCGKMGYTETSLQEHVTSEHAETSTEVICPICAALPGGDPNHVTDDFAAHLTLEHRAPRDLDESSGVRHVRRMFHPGRGLGGPRARRSNMHFTSSSTGGLSSSQSSYSPSSREAMDPIAELLSQLSGVRRSAGGQLNSSGPSASQLQQLQMQLQLERQHAQAARQQLETARNASRRTNTSSVTTTITQATATANTANTENSPQALHNSQFLLTRLNDPKMSEAERQSMESERADRSLFVQELLLSTLVREESSSSDEDDRGEMADFGAMGCVDIMPLDVALENLNLKESNKGNEPPPPPL
What is the function of this protein?
Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination.
What are the official names of this protein?
E3 ubiquitin-protein ligase KCMF1, Differentially expressed in branching tubulogenesis 91, Debt-91, RING-type E3 ubiquitin transferase KCMF1.
What is the protein family that this protein belongs to?
Belongs to the KCMF1 family.
Protein: YBED_ECOUT
Sequence: MKTKLNELLEFPTPFTYKVMGQALPELVDQVVEVVQRHAPGDYTPTVKPSSKGNYHSVSITINATHIEQVETLYEELGKIDIVRMVL
What are the official names of this protein?
UPF0250 protein YbeD.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: Y3517_COLP3
Sequence: MLCAIYKSARKAQTYLFVNKRDDFSSVPEGLMKTFGTPNLVTLINLATKDKLAMADLEKVKKNLIEKGFYLQLPPPQEDLLKEHKAAMAAEKEQGEL
What are the official names of this protein?
YcgL domain-containing protein CPS_3517.
Protein: YTFE_ECO5E
Sequence: MAYRDQPLGELALSIPRASALFRKYDMDYCCGGKQTLARAAARKELDVEVIEAELAKLAEQPIEKDWRSAPLAEIIDHIIVRYHARHREQLPELILQATKVERVHADKPSVPKGLTKYLTMLHEELSSHMMKEEQILFPMIKQGMGSQAMGPISVMESEHDEAGELLEVIKHNTNNVTPPPEACTTWKAMYNGINELIDDLMDHISLENNVLFPRALAGE
What is the function of this protein?
Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions.
What are the official names of this protein?
Iron-sulfur cluster repair protein YtfE.
What is the protein family that this protein belongs to?
Belongs to the RIC family. YtfE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOSM_YEAST
Sequence: MSENNEFQSVTESTTAPTTSNPYGPNPADYLSNVKNFQLIDSTLREGEQFANAFFDTEKKIEIARALDDFGVDYIELTSPVASEQSRKDCEAICKLGLKAKILTHIRCHMDDARVAVETGVDGVDVVIGTSKFLRQYSHGKDMNYIAKSAVEVIEFVKSKGIEIRFSSEDSFRSDLVDLLNIYKTVDKIGVNRVGIADTVGCANPRQVYELIRTLKSVVSCDIECHFHNDTGCAIANAYTALEGGARLIDVSVLGIGERNGITPLGGLMARMIVAAPDYVRSKYKLHKIRDIENLVADAVEVNIPFNNPITGFCAFTHKAGIHAKAILANPSTYEILDPHDFGMKRYIHFANRLTGWNAIKSRVDQLNLNLTDDQIKEVTAKIKKLGDVRPLNIDDVDSIIKDFHAELSTPLLKPVNKGTDDDNIDISNGHVSKKAKVTK
What is the function of this protein?
Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate.  Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway.
What are the official names of this protein?
Homocitrate synthase, mitochondrial, HCS.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SKI8_YEAST
Sequence: MSKVFIATANAGKAHDADIFSVSACNSFTVSCSGDGYLKVWDNKLLDNENPKDKSYSHFVHKSGLHHVDVLQAIERDAFELCLVATTSFSGDLLFYRITREDETKKVIFEKLDLLDSDMKKHSFWALKWGASNDRLLSHRLVATDVKGTTYIWKFHPFADESNSLTLNWSPTLELQGTVESPMTPSQFATSVDISERGLIATGFNNGTVQISELSTLRPLYNFESQHSMINNSNSIRSVKFSPQGSLLAIAHDSNSFGCITLYETEFGERIGSLSVPTHSSQASLGEFAHSSWVMSLSFNDSGETLCSAGWDGKLRFWDVKTKERITTLNMHCDDIEIEEDILAVDEHGDSLAEPGVFDVKFLKKGWRSGMGADLNESLCCVCLDRSIRWFREAGGK
What is the function of this protein?
Involved in double-strand break (DSB) formation during meiotic recombination through stabilization of SPO11 association with meiotic chromosome and helping SPO11 to recruit other DSB proteins like REC102 and REC104 to meiotic chromosomes.  Also a component of the SKI complex involved in 3'-mRNA degradation pathway.  Represses dsRNA virus propagation by specifically blocking translation of viral mRNAs, perhaps recognizing the absence of CAP or poly(A).  Essential for controlling the propagation of M double-stranded RNA (dsRNA) and thus for preventing virus-induced cytopathology.
What are the official names of this protein?
Antiviral protein SKI8, Superkiller protein 8.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome. Note=Relocalizes from the cytoplasm to the nucleus and is recruited to chromosomes by SPO11 during meiotic prophase.
Protein: QCR2_NEUCR
Sequence: MISRSALSRGSQLALRRPAAAKTAQRGFAAAAASPAASYEPTTIAGVKVASRDDSGPTTRLAVVAKAGTRYEPLPGLTVGLEEFAFKNTNKRTALRITRESELLGGQLQAYHTREAVVLQASFLREDLPYFTELLAEVISETKYTTHEFHELVENCIHEKQAKLDSAAIALDAAHNVAFHSGLGSPLYPTVDTPTSSYLNENSVAAFANLAYNKANIAVVADGASQAGLEKWVEPFFKGVPATSSGNLNTAASKYFGGEQRVAKNGKNAIVIAFPGASLGVPHPETSVLVGLLGGVSNIKWSPGFSLLAKATAANPGAEAFAHNYAYSDAGLLAIQITGKGAAVGKVAVEAVKGLKAIAAGGVSKEDLTKAIAKAKFNLLSASEVSGTGLVHAGANLLAGGKPIQVAETLKALEGVTAEKLQAAAKKLLEGKASVSAVGDLHVLPYAEDLGLKV
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
What are the official names of this protein?
Cytochrome b-c1 complex subunit 2, mitochondrial, Complex III subunit II, Core protein II, Ubiquinol-cytochrome c oxidoreductase complex core protein 2, Ubiquinol-cytochrome c reductase complex 45 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family. UQCRC2/QCR2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: GLPK_DESHD
Sequence: MKKYVLALDQGTTSCRAILFDRESQIVGVAQKEFTQIYPQPGWVEHDPEEVWSTQYGVIAELLARYQVTSEEIAGIGITNQRETTVVWDKHTGKSVTNAIVWQCRRTAPLCDELKMKGLEPLFKEKTGLVLDAYFSGTKIRWILDRVPGAQEKAEKGELLFGTMDTWLVWNLTKGRIHVTDYSNASRTLLYNIKTLAWDPDLLQVLNIPLAMLPEVKPSSTIYGETAAEGLFGHPIPIAGIAGDQQAALFGQACFAPGMAKNTYGTGCFMLLNTGEELYESRHGLISTIAWGLDEKVIYALEGSVFMAGAVMQWLRDELKLIETAGDSEYFAGKVADNGGVYLVPAFTGLGAPYWDMDARGAIVGLTRGSNKNHIIRAALESMAYQTRDILEAMEADSQLPLQLLKVDGGAVVNNLLMQFQADILGVEVERPHCIETTALGAAYLAGLAIGFWSSKEELRDKAKMERSFKPQMAEERKEKYYQGWHKAVRQIME
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: HIS5_AROAE
Sequence: MSDVAIIDYGMGNLRSVAKAIEHVAPGKRVAVTSDPAVVAAAARVVFPGQGAMPDCMRELDLRGLREVVKTAAASKPFLGICIGQQMLFEHSEEGNVPGLGILPGGVVRFPDAKMVAADGSRLKVPHMGWNEVCQRKPHPMWEGIPDNERFYFVHSYFVAPADAALVAAESDYGTRFTSAVARANIFAVQFHPEKSAQAGLKMLANFISWAP
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_MYXXD
Sequence: MRAVVQRVLEASVTVEGQRVSDIGPGLLVLLGVGKGDTEADVAWMVEKLATLRIFEDAAGKMNLSLEETSRQLIVVSQFTLYGDARKGRRPSFIDAMEPVSAKALYERTCELLRQRGLSVGTGIFAADMKVALVNDGPVTLLLESPGPAAPKG
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: B561A_ARATH
Sequence: MCDQRPNLLGSLVLLGFFIFFVNGEECSNSSSLIGHESEFKMLQHQLRGVFTVVDDCSFRVSRFDMLSGSEVHWWGAMSSDFDNMTNDGFVISDQKLNQTFKNSSFIVRLLGNVTWDKLGVVSVWDLPTASDFGHVLLSNATESDTSKAESPPSESNDVAPGKSNNSEPFKAPTMFDNCKKLSDKYRLRWSLNAEKGYVDIGLEATTGLLNYMAFGWAKPNSTSNLMLNADVVVTGIREDGFPFADDFYITESSVCSVKEGTATGVCPDTVYEEADSVGSSVNNTKLVYGHRIDGVSFVRYRRPLNDSDNKFDFPVNSTESLTVIWALGVIKPPDVINPYYLPVNHGGVESENFGHFSLNLSDHVDECLGPLDADNKYDQDVIIADAHAPLVVTAGPSVHYPNPPNPSKVLYINKKEAPVLKVERGVPVKFSIEAGHDVSFYITSDFLGGNASLRNRTETIYAGGQETHGVLSSPSELVWAPNRNTPDQLYYHSIFQEKMGWKVQVVDGGLSDMYNNSVNLDDQQVKFFWTIVGDSISIAARGEKKSGYLAIGFGSEMTNSYAYIGWFDRNGTGHVNTYWIDGESASAVHPTTENMTYVRCKSEEGIITLEFTRPLKPSCSHRDRPECKNMIDPTTPLKVIWAMGAKWTDGQLTERNMHSVTSQRPVRVMLTRGSAEADQDLRPVLGVHGFMMFLAWGILLPGGILSARYLKHIKGDGWFKIHMYLQCSGLAIVFLGLLFAVAELNGFSFSSTHVKFGFTAIVLACAQPVNAWLRPAKPAQGELISSKRLIWEYSHSIVGQSAVVVGVVALFTGMKHLGERNGTENVDGLNLALGLWVFLCVVTVAYLEYRERGRRRARNLSRGNWVLGNVEEDDSIDLIDSRGGFRDKDDEDRNGGRMEIQLEPLK
What is the function of this protein?
May act as a catecholamine-responsive trans-membrane electron transporter.
What are the official names of this protein?
Cytochrome b561, DM13 and DOMON domain-containing protein At5g54830, Protein b561A.tha1.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RPOZ_STRTD
Sequence: MMLKPSIDKLLDKVPSRYSLVILQAKRAHELAAGAEPTQEFSSVKYTLQALEEIESGNVIIHPNPEAKRKLARLKVIQARLAAEEEERKIKEQIAKEKEEGDKI
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: SYFA_XANOP
Sequence: MSEIQSLTERALADVAAAQTPDQLEALRVALLGKSGSITAQLKQLGTLPADQRKAAGEAINLSRDALTAALAERKNTLETAALDARLAGERIDVTLPGRRSERGGLHPVTRTLERIVEIFARLGYELSDGPEIEDDWHNFEALNFPPHHPARAMHDTFYFGDGRLLRTHTSGVQVRYMDAHKPPLHMIAAGKVYRSDSDQTHSPMFHQLEGLLVDEHSTFADLKGTLSEFVRAFFERDFEMRFRPSYFPFVEPGAEVDIAWQQPDGSTRWLEVLGCGMVHPNVLRNVGIDPERYTGFAFGLGVERFAMLRYGVNDLRAFFENDVRFLRQFA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_TREPA
Sequence: MEHTDVVIAPVLTEKSNALRQQGKYVFRVAARATKIQIKQAVTQLFGVTVRRCTVMNVFGKKRRVRHRTGRTSGWKKAIVHVAAGQSIGVLERA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: HTPX_MYCLB
Sequence: MTWHPQANRLKTFVLLVGMSTLIVVVGAIFGRTALFFATLVAVGINVYTYYNSDKLALRAMHAQPVSEVQAPVMYRIVRELATGAHQPMPRLYISDTNAPNAFATGRNPRNAAVCCTTGILEILNERELRAVLGHELSHVYNRDILISCVAGALAGVITALANMAMWAGTFGTTRDEENPFALLLVSLLGPIAATVVRLAVSRSREYQADESGAMLTGDPLALASALRKISSGVQAAPLPPEPQLASQAHLMIANPFRVGDRIGSLFSTHPPIEDRIRRLETMVAGR
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSMA_THEFY
Sequence: MTESDSADARLLTPADVRRLAAQLGIRPTKTLGQNFVIDPGTVRRIVRAAQVSPDDVVVEVGPGLGSLTLALLPHVRHVTAVEIDPRLAEALPGTVADHAPAYAHRLRVVTADALRITELPDPQPTALVANLPYNVAVPVVLHLLNLLPSLEHGLVMVQAEVAERLAARPGDRAYGAPSAKIAWYADVRRAGAIGRTVFWPVPNVDSGLVALRRRPAPPTKASREDVFAVVDAAFAQRRKTLRAALSSWAGSAAAAEAALRSAGVDPRSRGETLGIADFARIAEHRP
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_LIGS1
Sequence: MKYFGTDGVRGIANETLSPELAFKLGRCGGYVLTQHASNKPARVLVARDTRISGQMLEQALIAGLLSVGIEVFSLGVMTTPGVAYLVRLQDADAGIMISASHNPVQDNGIKFFGSDGYKLSDEKEEEIEALLESDEDTLPRPSAEGLGTLSDYREGALKYTQFLEQTIPDDLEGMHIAVDGANGSTSALVSRLFADLGADFDTMATNPDGLNINKGVGSTHPEALAKFVVEKGAQVGVAFDGDGDRCIAVDENGEIVDGDKIMFICGKYLSERGRLKKDTIVTTVMSNIGLYKAMKENNLNSVQTKVGDRYVVEAMRKDGYNVGGEQSGHVVFLDFNTTGDGMLTALQLLNVIKQTGKKLSELAAEVKTYPQELVNIKVTDKKAALDNEKIKEAIAKVEEKMAGDGRVLVRPSGTEDLLRVMAEAKTQELVHDYVMEIADVVEAEMGVNE
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.