PharMolix/UniProtQA huggingface dataset:
Protein: SCC3_CAEEL
Sequence: MSETPTDQSPQRMSTRNQARVNYTDMAAGNNSVEKEPVFRSPTASTRGRKKRAANVDVADLSASFGNLNNFSTPPKRGRPRGGGLGSARGGRAPMVRRTTTEESAEVDDRELVAAVKSGKKITEAVDRWIGRYNEKFLVAIAEMHQFFFAICGCKGIVTPQMSATLTYKDIICRMTEDFEEDSADYPLVHGGSLKKVRANLHNFIHTLIIRTKASMLFDSNLMDGFVQLLTGMADSQVRAFRHTATFCAMKITSALVDVTIELTQSKEKTSKQIEAEKAKLKNNSAGNEKYEALVAQRTQTEERAEEIRQIIGYLFRSVFVHRYRDVVPDIRCICIQELGHWMDVYPEHFVEDSYLKYIGWSMFDKVGDVRQRCIRALIPLFEKTLILDKLELFVNKFKDRLVSMLLDKDLETSIETVHLMRVLYTVFPTLLTIKDVVPIYELIYASNRPLAVAAGMFLNTKVFRSAEKPGKAPTAANIPLVKDLTTFFIEGDLHQHATYLVDALFESNPIVKDWATMGELLINDQYQLDSNFETKLIEILTCSVVQSATGEPPVGRHIVKKGAPSAKESRDLVEDRQRLTETLIPLIPRLITKFSSDNEKIINLVNIPLHFQLETYLSARMQTHLMELMEGLDSLIEKHLDEELLKAVAELYYHLTTNSSISALVEGHKMKLLDGVAAFIRKSMQQFDDDQMGEEEEALFVSYIKRMAAFAGFMDLRHWDLWDILLKVVSNYTREDTQRDVRERSMQMLFMQLCFDSMNIKKEGETPKADQVRKLKKRRDQLIRIVTETLNEEACGVEQAYLVICDLMILFGSQLAEESKALEPLIWRPDAMVLGNLKIFLDVNVFDVSNLDDMDQQEKIEVMHKMRQHVAQYAKLIIHGAMPVAEASHLIKRYQSHFQDFGDIFKNLLSKCREISFVETGVMICETLKTLYSQLDEDQGTDPLSESFNSIRDLAKRLGPAFGVDYAKNRFAISSLHKKAIDFAFEEYDKENHQMPKNIFFLEIAIEFSGKLLAQDKMAVVRYLNKIYTNRVGTSTVVWEPYRLYLGSLSDRNDDDNMSVRSGMTVTSNATMRSTASSTRGRGRGRGRSRIADDF
What is the function of this protein?
Component of the cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication (PubMed:12827206).  The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped (By similarity).  At anaphase, the scc-1 subunit of the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate (By similarity).  The cohesin complex may also play a role in spindle pole assembly during mitosis (By similarity).  Plays an essential role in cell division during embryonic development (PubMed:12808038, PubMed:14560015, PubMed:12827206, PubMed:16802858).  Required for the assembly of the synaptonemal complex between homologous chromosomes to promote sister chromatid cohesion during mitosis and meiosis (PubMed:14499625, PubMed:14560015).  Has a role in stabilization of homologous chromosome associations during meiotic synapsis (PubMed:12827206).  Required for chromosome segregation during mitosis and meiosis (PubMed:14499625, PubMed:12808038, PubMed:14560015, PubMed:16802858).  Plays a role in DNA double-strand break (DSB) repair during meiotic recombination and promotes the assembly of the 9-1-1 cell-cycle checkpoint response complex which is required for inducing apoptosis in response to DNA damage, at DNA damage sites (PubMed:21856158).
What are the official names of this protein?
Cohesin subunit scc-3.
What is the protein family that this protein belongs to?
Belongs to the SCC3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Has diffuse nuclear appearance at interphase during mitosis in somatic and germline tissues (PubMed:12827206). Localizes to chromosomes at pachytene during meiosis (PubMed:14499625).
Protein: AMY_STRTL
Sequence: MASRTLSGALALAAAATAVLAAPATVAHRSPPGTKDVTAVLFEWDYVSVAKECTSTLGPAGYGYVQVSPPAEHIQGSQWWTSYQPVSYKIAGRLGDRAAFRSMVNTCHAAGVKVVVDTVINHMSAGSGTGTGGSSYTKYDYPGLYSAPDFDDCTAEITDYQDRWNVQHCELVGLADLDTGEEYVRQTIAGYMNDLLSLGVDGFRIDAATHIPAEDLANIKSRLSNPNAYWKQEVIYGAGEPPKPGEYTGTGDVQEFRYAYDLKRVFTQEHLAYLKNYGEDWGYLSSTTAGVFVDNHDTERNGSTLNYKNDATYTLANVFMLAWPYGAPDINSGYEWSDPDARPPDGGHVDACWQNGWKCQHKWPEIASMVAFRNATRGEPVTDWWDDGADAIAFGRGSKGFVAINHESATVQRTYQTSLPAGTYCDVQSNTTVTVDSAGRFTAALGPDTALALHNGRTSC
What are the official names of this protein?
Alpha-amylase, 1,4-alpha-D-glucan glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: ACPS_LACJO
Sequence: MIRGVGIDSVEVERMKKIVEKGDKFAKRVLTPKEFEQYQQLKGKRKVEYLGGRFSLKESFSKAMGTGLGKYVGFQDIETLWDDLGHPVMTSTKFSGNIFPSITHDDHEIITVVVLEELN
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RB11A_LOTJA
Sequence: MASGGGYGDANAKIDYVFKVVLIGDSAVGKSQILARFARNEFSLDSKSTIGVEFQTRTLVIDHKTVKAQIWDTAGQERYRAVTSAYYRGAVGAMLVYDITKRQTFDHIPRWLEELRNHADKNIVIILIGNKCDLVNQRDVPTEDAKEFAEKEGLFFLETSALEATNVESAFTTVLTEIYNIVNKKSLAADESQGNGNSASLSGQKIIIPGPAQEIPAKRNMCCQAS
What are the official names of this protein?
Ras-related protein Rab11A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: SYI_VIBCM
Sequence: MSEYKDTLNLPETGFPMRGDLAKREPEMLQRWYQEDLYGAIRQAKKGKKSFVLHDGPPYANGDIHIGHALNKILKDVIIKSKTLSGFDAPYIPGWDCHGLPIELMVEKKVGKPGQKVTAAEFREKCREYAAGQVEGQKESFKRLGILGEWDKPYRTMDFVTEANIIRALGKIADNGHLLKGFKPVHWCTDCGSALAEAEVEYKNKVSPSIDVRFKAADEAAVLAKFGLAAGHEGKGDVSIVIWTTTPWTLPANRAVCLRADLEYVLIQVEGEQPERIIVASELAKSVMDRAGIEHFHNLGFATGADLELVQFQHPFYSFTVPAILGDHVTTDSGTGVVHTAPGHGQEDFAVGQQYGLEVANPVGSNGVYLPDTELFAGQHVFKANDSVLEVLKEKGALLHHHAYEHSYPHCWRHKTPIIFRATPQWFVSMEQAGLREQALTAIKGVHWMPDWGQSRIEGMVAGRPEWCISRQRTWGVPIALFVHKETAELHPNSADLIEKVAQLVEQKGIQAWWDLDTAELLGAEDAANYEKVLDTLDVWFDSGVTHSAVVDARQEFNGAEADMYLEGSDQHRGWFQSSLISSVAMKGKAPYKEVLTHGFVVDGQGRKMSKSIGNVVAPQDVTNKLGADILRLWVASTDYTGEVAVSDEILKRSADAYRRIRNTARFFLANLNGFNPTTDIIPVEDMVALDRWAVGRALAAQQEIIQAYQDYNLHAVVQRLMNFCSIEMGSFYLDVIKDRQYTAKRGGHAQRSCQTALFFIVEALVRWMAPIMSFTADEIWNAMPAQQADGSARDKFVFTTEWFDGLFGLAEGEELNNAFWNDIQKVRGSVNKLLENARNEKLIGGSLQAELVLFADDSLASKLAKLGDELRFVLLTSKAVVKPLAEKSEAAQATDIDGLFVQVNKTEAEKCDRCWHHTPDVGTIAGHTTICGRCVSNVEGEGEVRKFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSMA4_STAA1
Sequence: MAIVGTIIKIIKAIIDIFAK
What is the function of this protein?
Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection.
What are the official names of this protein?
Phenol-soluble modulin alpha 4 peptide.
What is the protein family that this protein belongs to?
Belongs to the phenol-soluble modulin alpha peptides family.
Protein: RS3A_SCHJA
Sequence: MAVGGQKKVTKGGKKGGKKKTADPFSKKEWYDIKAPAMFPKRTCARTLVTRTQGTRIASEALKGRVVTLSLGDLSEKNEEVFRKFKLQIEDVQGRHCLTNFHGLELTRDKLCSVVVKWRSTIEAHVDVKTTDGYLLRFFIITFTPSVPRSERLHSYAQTTRIKRIRARLVEIIQQEVSTCDLKEVVNKLIPDSIAQDARKAASWIYPLGETFIRKVKVLKRPKADLARLMELHGESKSTAPGETVSRPDHYEPPKVDSV
What are the official names of this protein?
40S ribosomal protein S3a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAA_MARSD
Sequence: MVLTDKIGRTVNYLRLSVTDRCNLRCMYCVTKDFKHIPHPDILRYEEMLRLVDLAASMNISKLRLTGGEPFARKGFMDFISQVMDSHPEIDLRITTNGTLIEPLVPELKKIGVSRLNISLDTLDRETFKEVTGRDHLTDVLATISACLSAGIRVKVNAVAMKGINDRELNSFIDFARENPIDMRFIEFMPMGDDTKSDSRFWSADDILEQGREYVNLIPVKRTAENRGPARMYSIEGGKGRLGLISPVSSHFCATCNRLRITSDGQLRTCLFSDKTYGLRDILRNPELGDDALRKVIAEATVDKPLGYHLLEQRSGCEGVCETQMSSIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: KCNA3_MOUSE
Sequence: MTVVPGDHLLEPEAAGGGGGDPPQGGCGSGGGGGGCDRYEPLPPALPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASPSQDVFEAANNSTSGAPSGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPSSGFNSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHSAFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
What is the function of this protein?
Mediates the voltage-dependent potassium ion permeability of excitable membranes.  Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
What are the official names of this protein?
Potassium voltage-gated channel subfamily A member 3, MK3, Voltage-gated potassium channel subunit Kv1.3.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.3/KCNA3 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PUR9_STAAN
Sequence: MKKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADYHEVLTRLRNDSLDESYRQSLMIKVFEHTAEYDEAIVRFFKGDKETLRYGENPQQSAYFVRTSNAKHTIAGAKQLHGKQLSYNNIKDADATLALVKKFDTPAAVAVKHMNPCGVGIGDTIEQAFQHAYEADSQSIFGGIVALNRAVTPELAEQLHSIFLEVIIAPKFTDEALDILKQKKNVRLLEIDMTIDSNEEEFVSVSGGYLVQDKDNYVVPKEEMKVVTEVAPTDEQWEAMLLGWKVVPSVKSNAIILSNNKQTVGIGAGQMNRVGAAKIALERAIEINDHVALVSDGFFPMGDTVELAAQHGIKAIIQPGGSIKDQDSIDMANKHGIAMVVTGTRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: LMNA_RAT
Sequence: METPSQRRPTRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLLAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTLKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQSQGGGSVTKKRKLESSESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLMTYRFPPKFTLKAGQVVTIWASGAGATHSPPTDLVWKAQNTWGCGTSLRTALINATGEEVAMRKLVRSLTMVEDNDDEEEDGDELLHHHRGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKAASGSGAQVGGSISSGSSASSVTVTRSFRSVGGSGGGSFGDNLVTRSYLLGNSSPRTQSSQNCSIM
What is the function of this protein?
Prelamin-A/C can accelerate smooth muscle cell senescence.  It acts to disrupt mitosis and induce DNA damage in vascular smooth muscle cells (VSMCs), leading to mitotic failure, genomic instability, and premature senescence.
What are the official names of this protein?
Prelamin-A/C.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Nucleus. Nucleus envelope. Nucleus lamina. Nucleus, nucleoplasm. Nucleus matrix. Note=Farnesylation of prelamin-A/C facilitates nuclear envelope targeting and subsequent cleavage by ZMPSTE24/FACE1 to remove the farnesyl group produces mature lamin-A/C, which can then be inserted into the nuclear lamina. EMD is required for proper localization of non-farnesylated prelamin-A/C (By similarity). Phosphorylation status of S-22 determines its localization between double-strand break (DSB) sites and the nuclear matrix (By similarity).
Protein: NDUAA_GORGO
Sequence: MALRLLKLGATSASARVVAAGAQRVRGIHSSGQCKLPYGMWHFLLGDKASKRLTERSRVITVDGNICTGKGKLAKEIAEKLGFKHFPEAGIHYPDSTTGDGKPLAADYNGNCSLEKFYDDPRSNDGNSYRLQSWLYSSRLLQYSDALEHLLTTGQGVVLERSIFSDFVFLDAMYNQGFIRKQCVDHYNEVKSVTICDYLPPHLVIYIDVPVPEVQRRIQKKGDPHEMKITSAYLQDIENAYKKTFLPEMSEKCEVLQYSAREAQDSKKVVEDIEYLKFDKGPWLKQDNRTLYHLRLLVQDKFEVLNYTSIPIFLPEVTIGAHQTDRVLHQFRELPGRKYSPGYNTEVGDKWIWLK
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial, Complex I-42kD, CI-42kD, NADH-ubiquinone oxidoreductase 42 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA10 subunit family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: P3URF_MOUSE
Sequence: MGPSQLVRAPRPPGLTSPYRRPGMGGPRRRCPSMFKCSRRTYRQKPRGPTATNPASEATNISDTDTTTSVLILSPRVLRFLCQPGGFLVL
What are the official names of this protein?
PIK3R3 upstream open reading frame protein.
Protein: RPOC1_PARMW
Sequence: MTNSNLRTENHFDYVKITLASPERVMEWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGFIKLAAPVSHVWYLKGIPSYVAILLDMPLRDVEQIVYFNCYVVLDPGDHKELKYKQLLTEDEWLEIEDEIYAEESEIENEPVVGIGAEALKQLLEDLNLEEVAEQLREEINGSKGQKRAKLIKRLRVIDNFVATSARPEWMVLDVIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDNGRRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQNIVNNIKAAKKLIQRADDEVMQVLQEVIDGHPIMLNRAPTLHRLGIQAFEPKLVDGRAIQLHPLVCPAFNADFDGDQMAVHVPLAIEAQTEARMLMLASNNILSPATGEPIVTPSQDMVLGSYYLTALQPGAEQPEFGDRSRTYSSLEDVIHAFEDTRIGLHDWVWVRFNGEVEDNDELDEPIKSETLSDGTRIEQWTYRRDRFDEDGALISRYILTTTGRVVMNHTIIGAVAAA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit gamma, RNAP subunit gamma, RNA polymerase subunit gamma, Transcriptase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
Protein: TRMB_SYNSC
Sequence: MRQHVNPLSSFFQLPLELPPPEQLFRVPDQPIHLDIGCARGRCLLGLAERDPHWNHLGVEIRRPLVTSADRDALASEHGNVRILFCNANISLEGWMKALKQDQLQRVSIQFPDPWFKRRHRKRRVLQPALLLAIATALQPGRELFLQSDVLNVIEPMVALTELSACFDRPVEDQRHWRASNPLSVPTERERYVLKQNLPVYRVLYRRNQNPLPSVSDLEQRWQEIDNPAEALTT
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: YGHE_ECOLI
Sequence: MIHQQHMRNIAQWLQENGITRATVAPDWMSIPCGFMACDAQRVICRIDECRGWSAGLALAPVMFRAQLNEQDLPLSLTVVGIAPEKLSAWAGADAERLTVTALPAITTYGEPEGNLLTGPWQPRVSYRKQWARWRVMILPILLILVALAVERGVTLWSVSEQVAQSRTQAEEQFLTLFPEQKRIVNLRSQVTMALKKYRPQADDTRLLAELSAIASTLKSASLSDIEMRGFTFDQKRQILHLQLRAANFASFDKLRSVLATDYVVQQDALQKEGDAVSGGVTLRRK
What is the function of this protein?
Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of folded proteins across the outer membrane.
What are the official names of this protein?
Putative type II secretion system L-type protein YghE, Putative general secretion pathway L-type protein YghE.
What is the protein family that this protein belongs to?
Belongs to the GSP L family.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: AROQ_RUEPO
Sequence: MTSILVLHGPNLNLLGTRQPEVYGTTTLEMVNSACIAHGQSRGLSVACLQSNHEGALVDAIHAAKGVHRGIVLNAGAYTHTSIALRDAISSVELPVVEVHLSNIHAREAFRHVSHIAPVALGQICGFGAQGYLLALDALAAHLSPEGAR
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: XERC_ECO57
Sequence: MTDLHTDVERYLRYLSVERQLSPITLLNYQRQLEAIINFASENGLQNWQQCDAAMVRNFAVRSRRKGLGAASLALRLSALRSFFDWLVSQNELKANPAKGVSAPKTPRHLPKNIDVDDINRLLDIDINDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHLDLESGEVWVMGKGSKERRLPIGRNALSWIEHWLDLRDLFGSEDDALFLSKLGKRISARNVQKRFAEWGIKQGLNNHVHPHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates.  The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.  In the complex XerC specifically exchanges the top DNA strands.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDI2_YEAST
Sequence: MSQYGFVRVPREVEKAIPVVNAPRPRAVVPPPNSETARLVREYAAKELTAPVLNHSLRVFQYSVAIIRDQFPAWDLDQEVLYVTCLLHDIATTDKNMRATKMSFEYYGGILSRELVFNATGGNQDYADAVTEAIIRHQDLTGTGYITTLGLILQIATTLDNVGSNTDLIHIDTVSAINEQFPRLHWLSCFATVVDTENSRKPWGHTSSLGDDFSKKVICNTFGYN
What is the function of this protein?
Cyanamide hydratase involved in the detoxification and/or utilization of cyanamide, a toxic nitrile compound distributed widely in the environment.
What are the official names of this protein?
Cyanamide hydratase DDI2, CAH, DNA damage-inducible protein 2.
What is the protein family that this protein belongs to?
Belongs to the cyanamide dehydrase family.
Protein: PSB8_BOVIN
Sequence: MALLDVCGAPGGQRGDWAVPLAGSRQRSDPGHYGFSLRSPELALPRGMQPTEFFRSLGGNGESKVQIEMAHGTTTLAFKFQHGVIVAVDSRASAGNYIATLKVNKVIEINPYLLGTMSGCAADCLYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVDENGTRLSGNMFSTGSGNSHAYGVMDSGYRPDLSIEEAYDLGRRAIVHATHRDSYSGGVVNMYHMKEDGWVKVESTDVSDLMHQYREASQ
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.  This subunit is involved in antigen processing to generate class I binding peptides (By similarity).  May participate in the generation of spliced peptides resulting from the ligation of two separate proteasomal cleavage products that are not contiguous in the parental protein (By similarity).  Required for adipocyte differentiation (By similarity).
What are the official names of this protein?
Proteasome subunit beta type-8, Proteasome subunit beta-5i.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LIPH_RAT
Sequence: MLRLCFLLSFMCLVKSDTDETCPSFTRLSFHSAVVGTGLSVRLMLYTQRDQTCAQVINSTALGSLNVTKKTTFIIHGFRPTGSPPVWMEELVQSLISVQEMNVVVVDWNRGATTVIYPHASSKTRKVALILKEFIDQMLAKGASLDNIYMIGVSLGAHIAGFVGEMYSGKLGRITGLDPAGPLFNGRPPEDRLDPSDAQFVDVIHSDTDALGYREALGHIDFYPNGGLDQPGCPKTIFGGIKYFKCDHQMSVFLYLASLQNNCSITAYPCDSYRDYRNGKCVSCGAGHIVSCPSLGYYADNWREYLWDRDPPMTKAFFDTAETKPYCIYHYFVDIISWNKSVRRGFITIKLRGEDGNITESKIDHEPSAFQKYHQVSLLARFNRDLDKVAEISLLFSTKSVVGPKYKLRVLRMKLRSLAHPDRPHLCRYDLVLMENVETFFQPILCSKQQM
What is the function of this protein?
Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid (By similarity).  Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG) (By similarity).
What are the official names of this protein?
Lipase member H.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted. Cell membrane; Peripheral membrane protein.
Protein: AGRE4_HUMAN
Sequence: MGSRFLLVLLSGASCPPCPKYASCHNSTHCTCEDGFRARSGRTYFHDSSEKCEDINECETGLAKCKYKAYCRNKVGGYICSCLVKYTLFNFLAGIIDYDHPDCYENNSQGTTQSNVDIWVSGVKPGFGKQLPGDKRTKHICVYWEGSEGGWSTEGCSHVHSNGSYTKCKCFHLSSFAVLVALAPKEDPVLTVITQVGLTISLLCLFLAILTFLLCRPIQNTSTSLHLELSLCLFLAHLLFLTGINRTEPEVLCSIIAGLLHFLYLACFTWMLLEGLHLFLTVRNLKVANYTSTGRFKKRFMYPVGYGIPAVIIAVSAIVGPQNYGTFTCWLKLDKGFIWSFMGPVAVIILINLVFYFQVLWILRSKLSSLNKEVSTIQDTRVMTFKAISQLFILGCSWGLGFFMVEEVGKTIGSIIAYSFTIINTLQGVLLFVVHCLLNRQVRLIILSVISLVPKSN
What is the function of this protein?
May mediate the cellular interaction between myeloid cells and B-cells.
What are the official names of this protein?
Putative adhesion G protein-coupled receptor E4P, EGF-like module receptor 4, EGF-like module-containing mucin-like hormone receptor-like 4, G-protein coupled receptor 127, G-protein coupled receptor PGR16.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Protein: DCAM2_BRAJU
Sequence: MSVSAIGFEGYEKRLEVSFFEPSLFVDTHGKGLRALPKSQIDEILAPAECTIVSSLSNDELDSYVLSESSLFIFPYKIIIKTCGTTKLLPSIEPLLRLAGELSLEVKSVRYTRGSFLCPGGQPFPHRNFSEEVSVLDGHFAKMGLSSVAYLMGDDDETKKWHVYSASAPARNGNGNNNNNVYTLEMCMTGLDKEKASVFYKNESSSAGSMTDNSGIRKILPQSQICDFEFEPCGYSMNSVEGDAISTIHVTPEDGFSYASFEAVGYDFTTMDLSHLVSKVLTCFEPKQFSVAVHSSVAQKSYDSGLSVDLEDYGCRETTIELLGEERGTVMYQSFEKLGRYCGSPRSTLKCEWSSSSSCTSEDEKEEGI
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme 2, AdoMetDC 2, SAMDC 2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic AdoMetDC family.
Protein: RM25_YEAST
Sequence: MSYKQYFDSLPLKLKSFFQRYPPSIKYSPVSTSTKAINANPFLPNKHPVTQRFHDPKYSLRRMSDVYKLALRYGVEEFLPPIENTKKLFFEEKYNKKTLMKGVLLPKGHKHELKLNEKLKKREEALKKVDELIASKKGSKYAKRVEKMKKNQSIGWF
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
What are the official names of this protein?
54S ribosomal protein L25, mitochondrial, Mitochondrial large ribosomal subunit protein mL59, YmL25.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL59 family.
Protein: NS12_CVHN2
Sequence: MEVWRPSYKYSLITREFGVTDLEDLCFKYNYCQPCVGYCIVPLNVWCRKFGKFASYFVLRSHDTSHKNNFGVITSFTSYGNTVSEAVSKLVESASDFIAWRAEALNKYG
What are the official names of this protein?
Non-structural protein 4, ns4, Accessory protein 4, Non-structural protein of 12.5 kDa, ns12.5, Orf4 protein.
What is the protein family that this protein belongs to?
Belongs to the coronaviruses ns12.7 protein family.