PharMolix/UniProtQA huggingface dataset:
Protein: IF5A2_MOUSE
Sequence: MADEIDFTTGDAGASSTYPMQCSALRKNGFVVLKGRPCKIVEMSTSKTGKHGHAKVHLVGIDIFTGKKYEDICPSTHNMDVPNIKRNDYQLICIQDGYLSLLTETGEVREDLKLPEGELGKEIEGKYNAGEDVQVSVMCAMSEEYAVAIKPCK
What is the function of this protein?
mRNA-binding protein involved in translation elongation.  Has an important function at the level of mRNA turnover, probably acting downstream of decapping.  Critical for the efficient synthesis of peptide bonds between consecutive proline residues.  Can resolve ribosomal stalling caused by consecutive prolines during translation (By similarity).  Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity.  Functions as a regulator of apoptosis.  Mediates effects of polyamines on neuronal process extension and survival.  May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 5A-2, eIF-5A-2, eIF-5A2, Eukaryotic initiation factor 5A isoform 2.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex. Note=Hypusine modification promotes the nuclear export and cytoplasmic localization and there was a dynamic shift in the localization from predominantly cytoplasmic to primarily nuclear under apoptotic inducing conditions.
Protein: ERG27_ASHGO
Sequence: MLICHQCLSSRLTYISNLGLNIAYRLIEQFTDDSKLVIVVTSRTLPRVREVVDLIKTYAEKCGKSGAVDFDYLLVDFTDMVSVLGAAYELEKRYDAIHYFYANAAQGVYSGIDWLGATKAVLRDPLDAVTNPTYKIQRVGVKSRDGLGLVFQANVFGPYYLIRRIIPLLAKGKAKVVWLSSLMSDVKYLSLEDVELLRTDSSYEGSKRLVDLLHLATYKELKSLGIHQYVTHPGIFTSHSFYQYLNFFTYYGMLFLFYLARWLGSPWHNIQGYKGANAPIYVATLANPTFEHQALKYGSATYRDGMEYIAKHEIDPTGMHDAYKYIRDLAEEWDIKLKDQITIGRSLS
What is the function of this protein?
Responsible for the reduction of the keto group on the C-3 of sterols.
What are the official names of this protein?
3-keto-steroid reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.
Protein: GLYCO_ARV
Sequence: MATFKVLVLMILWITSIFNVRCEKFVTIPVNCSGEVDIDKMDVMCPNRYNLLSTNHLMEGEEVETFCRPSLRENDLLDGYLCRKQKWEVTCTETWYFVTDVKYQIIEVIPTENECMEERERKLKGEYIPPYYPPTNCVWNAIDTQERTFITLIEHPVIEDPVTMTLMDSKFTKPCNPKHNEVTICDTYNPLIKWISKETSGLNLHCQIKSWECIPVKLHHSHRNMMEALYLESPDFGIVDASKICNLTFCGYNGILLDNGEWWSIYRSGFTHGFLDNHILKNRRIEECKEKKPGYKLAKLDTTYIDLEFEIELEHEKCLGTLEKLQNGEYVTPLDLSYLSPSNPGKHYAYRLEYINTTEHKCVQLGFTYEGGDCRKMLDERDDHGAYYNWTTIKLQRVIRAVCYYHTFSMNLDESKHKYYDQDNRSIQIDEKFISEVLKSTPLIDRHEKYEGNLSWNGIIIESKNGHEKNVIVPSASQYNHVMINKILKRLDTVMYDSYKFDSESGSISYNKIVPIVREDNLQNAHRVDVIQYIKDKGSYIINGFTGWFSSLGKLMRWTIWGVGLFFSIFTLYKIIMILRKHSNDNVRKEFKETAGKVMIGQPIDTKSMSRTSIKANNKGKFDKVKDLFTPRSKTISHLTTDTLKEHTDGTYEELHFFNV
What is the function of this protein?
Attaches the virus to host cellular receptor, inducing endocytosis of the virion.  In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane (By similarity).
What are the official names of this protein?
Glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the ephemerovirus glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein.
Protein: CLPX_STAAE
Sequence: MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAMTELPTPKEIMDHLNEYVIGQEKAKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENILLRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTNILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNILTQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEETEPELYDAEGNLINNSKTSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: YAEP_ECO8A
Sequence: MEKYCELIRKRYAEIASGDLGYVPDALGCVLKVLNEMAADDALSEAVREKAAYAAANLLVSDYVNE
What are the official names of this protein?
UPF0253 protein YaeP.
What is the protein family that this protein belongs to?
Belongs to the UPF0253 family.
Protein: FLIT_YERPE
Sequence: MERHQHLLSEYQQILTLSEQMLMLATVENWNALVDLEMTYLKAVENTANITISSCTSPVLQELLRQKLRSILENEIEIKRLLQRRLDKLSELVGQSTRQQAVNRTYGQFPDQALLLGETQ
What is the function of this protein?
Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD.  As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons.  As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.
What are the official names of this protein?
Flagellar protein FliT.
What is the protein family that this protein belongs to?
Belongs to the FliT family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: PP244_ARATH
Sequence: MMLVVSENYLLSPSLYLKALKLCSYQNVKKQLLLIHGNSITNGFCSNLQLKDMLIDLYLKQGDVKHARKLFDRISKRDVVSWTAMISRFSRCGYHPDALLLFKEMHREDVKANQFTYGSVLKSCKDLGCLKEGMQIHGSVEKGNCAGNLIVRSALLSLYARCGKMEEARLQFDSMKERDLVSWNAMIDGYTANACADTSFSLFQLMLTEGKKPDCFTFGSLLRASIVVKCLEIVSELHGLAIKLGFGRSSALIRSLVNAYVKCGSLANAWKLHEGTKKRDLLSCTALITGFSQQNNCTSDAFDIFKDMIRMKTKMDEVVVSSMLKICTTIASVTIGRQIHGFALKSSQIRFDVALGNSLIDMYAKSGEIEDAVLAFEEMKEKDVRSWTSLIAGYGRHGNFEKAIDLYNRMEHERIKPNDVTFLSLLSACSHTGQTELGWKIYDTMINKHGIEAREEHLSCIIDMLARSGYLEEAYALIRSKEGIVSLSSSTWGAFLDACRRHGNVQLSKVAATQLLSMEPRKPVNYINLASVYAANGAWDNALNTRKLMKESGSCNKAPGYSLVY
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At3g20730.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-E subfamily.
Protein: DEOB_OCEIH
Sequence: MNNFKRVFLIVMDSVGIGEAPDARDFNDVGANTLGHIAENMNGLNMPTMASLGLSNIRKIEGIEASAQPRAHYTKMQEASNGKDTMTGHWEIMGLHIEKPFRTFPDGFPDELIEELEQKTGRKVIGNKPASGTEILDELGQQHMDTGSLIVYTSADSVLQIAAHEEIIPIDEQYRICEIARELTLDEKYMVGRVIARPFIGEPGAFERTSNRHDYALKPFGRTVMNELKDNNYDVLALGKISDIYDGEGVTESIRTKDNNDGMVQLRKSMDKSFTGLNFLNLVDFDAKYGHRRDPVGYGKALEEFDEQLPEIIEQLHDDDLLIITADHGNDPIHHGTDHTREYVPLVVYHNQIKQAKELPIRKTFADIGATIADNFGIKLPEHGESFLNDIK
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_MYCA1
Sequence: MARADKATAVADIAEQFKEATATLITEYRGLTVANLAELRRSLSGAATYSVAKNTLVKRAASEAGIEGLDELFAGPTAIAFVTGEPVDAAKAIKTFAKEHKALVIKGGYMDGRALSVAEVERIADLESREVLLAKLAGAMKGNLAKAAGLFNAPASQVARLAAALQEKKAAECPAEAPQPAAETPAEAPEAPADAE
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: PSAC_POPTR
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLWHETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: P7_GLRV3
Sequence: MRHLEKPIRVAVHYCVVRSDVCDGWDVFIGVTLIGMFISYYLYALISICRKGEGLTTSNG
What are the official names of this protein?
Protein P7, 7 kDa protein.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: CL067_HUMAN
Sequence: MLPFFSNTTSKSVSVSSFQGSPATPLSFLFFFFLCRAGSSMTGCFTFFLDFIFFFAGVLGPSPMGMYSGASTLTGFFLLRFLGQLSMDLEGLEWLGRASPSWWIFFSSSPSHRVPWGSCASASAPRLPVPHPPSPLSKCPQHPRPRRTKGPGLRKLWGPGPPFFPS
What are the official names of this protein?
Putative transmembrane protein encoded by LINC00477.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BGLK_EMENI
Sequence: MGEISPRGGDFDIDYILENASSLEKISLLAGHDFWHTAPLPRFNVPSVRVSDGPNGVRGTKFFDGVRAACLPCGTGLAATWDQSLLFDAGVLIGQECLAKGAHCWLGPTVCIQRSPLGGRGFESFAEDPYATGKLAAAYIRGAQSTGVISTIKHFAANDQEHERISVNAVMSERALREVHLLPFQIAIADAAPGAVMTCYNKINGQHVSESKEMLDGLLRKEWGWKGLIMSDWFGTYSTAEALNAGLDLEMPGPTRLRGPLLELAISSRKVSRSTLDERARTVLEFVKRANKAEVSTVESTRDFPEDRRLNRKLAADSIVLLKNESGLLPLNLKALKSAALIGPNMKTAAFCGGGSASLQPYYSISPYQGIMNQLPPGVEIIYETGASSYVFIPELEASEVRTPEGQPGLRMRFYREPPSVKERRVVEETILQESSWQLMGFSNPQLDRLFYADIEAELIAPATGPFEFGLAVYGSGSLFIDDQLIIDNTTVQRGGNFFFGKGTREEKATVDLVKGQLYKIRVEFASGPSSKLMKPGVVNFGGGAGRLGMVQAIDPELAIARAVEAAKRADVTILGVGLTRDHESEGFDRSHMDLPPAVASLVTAVLDVAPDAILMTQSGTPFNMLPWADNVKTHLHAWFGGNELGNGIADVLFGVVNPSGKLPLSFPRRIEDTPTYLNFGSERGQVTYGEGIYVGYRYYEKVLRDVLYPFGHGLSYTSFAYSDFAVDTASATLNVRNSGDVAGAEVVQLYIAADATTSSIARPVKELKGFAKVTLQPGETCSVSIPFDRFTTAFWDQEAHVWTCEKGQYRVMVGSSSQNILLEGVLEIKETTTWSGL
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
What are the official names of this protein?
Probable beta-glucosidase K, Beta-D-glucoside glucohydrolase K, Cellobiase K, Gentiobiase K.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RLMH_SHIBS
Sequence: MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRGKNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLAAELERWKLDGRDVSLLIGGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_BORA1
Sequence: MAIDNRLLPNTLAAQAAALPSAWSQALAAPGVAQALDHIINHVEARLAAGATVYPATPLRALSSLAPSEVRVVILGQDPYHGPGQAQGLAFSVPDDCKCPPSLRNIFKEIGRDYALDGKPGHDLTPWVKQGVLLLNTALTVEDGQPASHAKRGWETVTDALFTQVAQDPTPKVFLLWGAHAQAKAALLPPGHAHLVLSANHPSPLSATRAPTPFIGCGHFRLTNEWLEKQGQTLIDWTATFKKIPAQAEFRL
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_BRADU
Sequence: MSDIGERVKKIVVEHLGVEPEKVVDAASFIDDLGADSLDTVELVMAFEEEFGCEIPDDAAETILTVGDATKFLEKNAKS
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YP02_SCHPO
Sequence: MNQDDFRKLLATPKAETSQLKNFSSNKSQRLVFGRKHKTAKLEAPRALIKRKQLSHSTSSDITRHSNAKNSGKDTQFYEEPSSKQDIELHKLHEKLRNGQITTKEYSEKSKELGGDLNTTHLVRGLDRKLLEKVRSNELALDDSLLSSSEKEVDEEADKLLEKVAEESSHPESVSILEEKKKIPLYPNGQPKYRKILENGKKVKYLLDENGEILKRLVKKEKKLKNDNERLENEHRTEKLNVNANSLGKSFVKHDIPLPPVDLKLDIFEEVGEYDPFHENDKEPAELKAKDAFQLKGHHELDAPYHKKVFDTNQYSDLKPTNFMSQIHRLAKVQERKEEEERKKGKDGQIVDAGFGLVLSKDDTADIHELGESDDDDNVKRRKTKG
What is the function of this protein?
Required for meiotic chromosome segregation.
What are the official names of this protein?
Meiotic chromosome segregation protein C1539.02.
What are the subcellular locations of this protein?
Nucleus.
Protein: NHR79_CAEEL
Sequence: MVRGKCMVCDSPNATNYHFGAQSCKACAAFFRRSIAMDQCYECLGDGVHSCKIDHTLRLNCRHCRLKKCQKAGMMRDLVQAKREIKSDKGKNSRNSSQSEDFFSPPPEQPGPSNYFDQFPWQASENEMDPYPSSPKIRKMSENLMGIDELQQFIQIPAGVDDFPDIFTDSDEIRSRMTSISEASAYVTGMEEEERLFGLAGLYTEQVINLNMRRRITYTDRLLGSVFDAPCVCPYDKADLKLFDHRTYRQKNRNDYTMILDYINRFPEFESLSKSEKTVLFRTAAAVDVLLDQSYYSQVIFPTEDVLVTANGEYLPMNPMPKVENQRDSGNFHSDEDYDRFKMLTSMKVRQWLHVCEPMKKLDMSLAEFSLFKALTIWHYNYYKLQCTGKQICSRQRDDIFRTLLLICDDEGHDSALIRASEIVLAVGIAMAEVHEMVTSYIEITVYDVLDDPILKDMLKFQY
What is the function of this protein?
Orphan nuclear receptor.
What are the official names of this protein?
Nuclear hormone receptor family member nhr-79.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RR16_CUCSA
Sequence: MVKLRLKRCGRKQRAAVYRIIAIDVRSRREGRDLRKVGFYDPIKNQTYLNVPAILYFLEKGAQPTGTVHDILKKAGVFTELHLNQ
What are the official names of this protein?
30S ribosomal protein S16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DEAD_BUCAI
Sequence: MTHIESTFSFLGLNPFIIQSLNEMGYVKPSPIQASCIPLLLEGRDVLGMAQTGSGKTAAFSLPLLHNLNINLKAPQILVLAPTRELAVQVAEAFSDFSKYMIGIHVLPLYGGQRYELQLRALRQGPQIVVGTPGRLLDHLKRGTLNLSNLHGLVLDEADEMLRMGFIEDVETIMAQIPKEHQTALFSATMPEAIRRISKRFMRNPKEIKIQSNITTRPDIKQSYWMVYGRKTDALIRFLEAEDFSATIIFVRTKNATLEVSEALERNGYNSAALNGDMNQALREQTLERLKNGRLDILIATDVAARGLDVDRISFVINYDIPMDSESYVHRIGRTGRAGRAGRALLFVENRERRLLRNIERTMKQSIPEVQLPKVELLCQRRLEQFAKKVQQQLESRDLDEYSALLDKLYSTDDLDIKTLAAALLKMAQGERPLIIKPDVIKRQSRDLLFQDDRRREDNRNSRTRRDRRDINKDAELYRIEVGRNDGVEVRHIVGAIANEGNINSRNIGNIKLFSSYSTIELPKGMSKDLLQTFNRTRILNKPINMKLLRDSRHYENKTTHRSIFNKDKNSNRRVSDGSFNKSNSPKKTEFKSSFFRRRNV
What is the function of this protein?
DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
What are the official names of this protein?
ATP-dependent RNA helicase DeaD, Cold-shock DEAD box protein A.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECB_ROSDO
Sequence: MAEEEEAKTEANGQQQAPQMRVLGQFIRDMSFENIMAQKGAPSDAQPDVQVQVNLDAKKRTADNQYESAIKLNVTSKVKDGDATLFVLELDYVGIFHVDNVPDEQLHPFLLIECPRMIFPFLRRIVSDITRDGGFPPLNLENIDFLSLYRNELARRQSSEAPKMDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_LEGPH
Sequence: MSRSSDLFHKAQTIIPGGVNSPVRAFKGVGGEPVFFKSGKGAYLTDVDDKQYIDYVGSWGPLILGHCHPKVIEAVDNVLHRGMSFGAPTELEIQLAEKIASLMPSIEKIRMVNSGTEATMTAIRLARGFTNKNKFIKFNGCYHGHSDSLLVKAGSGLLTLGIPSTPGIPQSITEHTLTADFNNLEQVAQLFEKYPNDIATVILEPIPGNMGFILPKIEFLKGLRELCDQYNALLIFDEVMTGFRVGLHGAQGLFGIKPDITTLGKIIGGGMPVGALGGKREIMSFLAPEGPVYQAGTLSGNPLAMAAGLATLKEIEKINFFEDLSNTTNKLTEALADAAENANIPFFAASLGGMFGFCFTDKNSVENYLDVASSDEVLFKKFFHAMLAQGVYFAPSMYEAGFVSSMHGDLEIQKTYDAAELVLNQLKSA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QPT2B_TOBAC
Sequence: MFRAIPFTATVHPYAITAPRLVVKMSAIATKNTRVESLEVKPPAHPTYDLKEVMKLALSEDAGNLGDVTCKATIPLDMESDAHFLAKEDGIIAGIALAEMIFAEVDPSLKVEWYVNDGDKVHKGLKFGKVQGNAYNIVIAERVVLNFMQRMSGIATLTKEMADAAHPAYILETRKTAPGLRLVDKWAVLIGGGKNHRMGLFDMVMIKDNHISAAGGVGKALKSVDQYLEQNKLQIGVEVETRTIEEVREVLDYASQTKTSLTRIMLDNMVVPLSNGDIDVSMLKEAVELINGRFDTEASGNVTLETVHKIGQTGVTYISSGALTHSVKALDISLKIDTELALEVGRRTKRA
What is the function of this protein?
Involved in the biosynthesis of pyridine alkaloid natural products, leading mainly to the production of anabasine, anatabine, nicotine and nornicotine, effective deterrents against herbivores with antiparasitic and pesticide properties (neurotoxins); nornicotine serves as the precursor in the synthesis of the carcinogen compound N'-nitrosonornicotine (NNN) (Probable) (PubMed:31276744).  Involved in the catabolism of quinolinic acid (QA) (Probable).
What are the official names of this protein?
Quinolinate phosphoribosyltransferase [decarboxylating] 2b, mitochondrial, NtQPT2b, QPRtase 2b.
What is the protein family that this protein belongs to?
Belongs to the NadC/ModD family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FOLB_STAAU
Sequence: MQDTIFLKGMRFYGYHGALSAENEIGQIFKVDVTLKVDLSEAGRTDNVIDTVHYGEVFEEVKSIMEGKAVNLLEHLAERIANRINSQYNRVMETKVRITKENPPIPGHYDGVGIEIVRENK
What is the function of this protein?
Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.  Can also catalyze the epimerization of carbon 2' of dihydroneopterin to dihydromonapterin.
What are the official names of this protein?
Dihydroneopterin aldolase, DHNA, 7,8-dihydroneopterin 2'-epimerase, 7,8-dihydroneopterin aldolase, 7,8-dihydroneopterin epimerase, Dihydroneopterin epimerase.
What is the protein family that this protein belongs to?
Belongs to the DHNA family.
Protein: 5HT2B_DROME
Sequence: MLKTVTTAMAAGDDDVPASILEIELPAILLNESLFIELNGNLTQLVDTTSNLSQIVWNRSINGNGNSNTFDLVDDEQERAAVEFWLLVKMIAMAVVLGLMILVTIIGNVFVIAAIILERNLQNVANYLVASLAVADLFVACLVMPLGAVYEISNGWILGPELCDIWTSCDVLCCTASILHLVAIAADRYWTVTNIDYNNLRTPRRVFLMIFCVWFAALIVSLAPQFGWKDPDYMKRIEEQHCMVSQDVGYQIFATCCTFYVPLLVILFLYWKIYIIARKRIQRRAQKSFNVTLTETDCDSAVRELKKERSKRRAERKRLEAGERTPVDGDGTGGQLQRRTRKRMRICFGRNTNTANVVAGSEGAVARSMAAIAVDFASLAITREETEFSTSNYDNKSHAGTELTTVSSDADDYRTSNANEIITLSQQVAHATQHHLIASHLNAITPLAQSIAMGGVGCLTTTTPSEKALSGAGTVAGAVAGGSGSGSGEEGAGTEGKNAGVGLGGVLASIANPHQKLAKRRQLLEAKRERKAAQTLAIITGAFVICWLPFFVMALTMSLCKECEIHTAVASLFLWLGYFNSTLNPVIYTIFNPEFRRAFKRILFGRKAAARARSAKI
What is the function of this protein?
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen.  The activity of this receptor is mediated by G proteins which inhibit adenylate cyclase.
What are the official names of this protein?
5-hydroxytryptamine receptor 2B, 5-HT receptor 2B, 5-hydroxytryptamine receptor 1B, 5-HT receptor 1B, Serotonin receptor 1B, Serotonin receptor 2B.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PCAB_ACIAD
Sequence: MSQLYASLFYQRDVTEIFSDRALVSYMVEAEVALAQAQAQVGVIPQSAATVIERAAKTAIDKIDFDALATATGLAGNIAIPFVKQLTAIVKDADEDAARYVHWGATSQDILDTACILQCRDALAIVQNQVQQCYETALSQAQTYRHQVMMGRTWLQQALPITLGHKLARWASAFKRDLDRINAIKARVLVAQLGGAVGSLASLQDQGSIVVEAYAKQLKLGQTACTWHGERDRIVEIASVLGIITGNVGKMARDWSLMMQTEIAEVFEPTAKGRGGSSTMPHKRNPVAAASVLAAANRVPALMSSIYQSMVQEHERSLGAWHAEWLSLPEIFQLTAGALERTLDVLKGMEVNAENMHQNIECTHGLIMAEAVMMALAPHMGRLNAHHVVEAACKTAVAEQKHLKDIISQVDEVKQYFNPSQLDEIFKPESYLGNIQDQIDAVLQEAKGEAK
What is the function of this protein?
Catalyzes an anti cycloisomerization.
What are the official names of this protein?
3-carboxy-cis,cis-muconate cycloisomerase, 3-carboxymuconate lactonizing enzyme, CMLE.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family.
Protein: TRA3_RHIME
Sequence: MAIEKELLDQLLAGRDPSEVFGKDGLLDDLKKALSERILNAELDDHLDVERLEGGPANRRNGSSKKTVLTGTSKMTLTIPRDRAGTFDPKLIARYQRRFPDFDDKIISMYARGMTVREIQGHLEELYGIDVSPDLISAVTDTVLEAVGEWQNRPLELCYPLVFFDAIRVKIRDEGFVRNKAVYVALAVLADGSKEILGLWIEQTEGAKFWLRVMNELKNRGCQDILIAVVDGLKGFPEAITAVFPQTIVQTCIVHLIRHSLEFVSYKDRRTVVPALRAIYRARDAEAGLKALEAFEEGYWGQKYPAIAQSWRRNWEHVVPFFAFPEGVRRIIYTTNAIEALNSKLRRAVRSRGHFPGDEAAMKLLYLVLNNAAEQWKRAPREWVEAKTQFAVIFGERFFN
What is the function of this protein?
Required for the transposition of the insertion element.
What are the official names of this protein?
Transposase for insertion sequence element ISRM3.
What is the protein family that this protein belongs to?
Belongs to the transposase mutator family.
Protein: PRGC1_PIG
Sequence: MAWDMCNQDSVWTDIECAALVGEDQPLCPDLPELDLSELDVNDLDTDSFLGGLKWCSDQSEIISNQYNNEPSNIFEKIDEENEANLLAVLTETLDSLPVDEDGLPSFDALTDGDVTTENEASPSSMPDGTPPPQEAEEPSLLKKLLLAPANTQLSYNECSGLSTQNHANHNHRIRTNPAVVKTENSWSNKAKSICQQQKPQRRPCSELLKYLTTNDDPPHTKPTETRNSSRDKCTSKKKAHTQSQSQHLQAKPTSLSLPLTPESPNDPKGSPFENKTIERTLSVELSGTAGLTPPTTPPHKANQDNPFRASPKLKPPCKTVVPPPSKKTRYSESSGTHGNNSTKKGPEQSELYAQLSKTSALGGGHEERKARRPSLRLFGDHDYCQSINSKAEILINISQELHDSRQLDSKDAASDWQRQMCSSTDSDQCYLTETSEASRQVSPGSARKQLQDQEIRAELNKHFGHPSQAVFDDEADKTSELRDSDFSNEQFSKLPMFINSGLAMDGLFDDSEDESDKLNSPWDGTQSYSLFDVSPSCSSFNSPCRDSVSPPKSLFSQRPQRMRSRSRSFSQHRSCSRSPYSRSRSRSPGSRSSSRSCYYSESGHCRHRTHRNSPLCARSRSRSPYSRRPRYDSYEEYQHERLKREEYRREYEKRESERAKQRERQRQKAIEERRVIYVGKIRPDTTRTELRDRFEVFGEIEECTVNLRDDGDSYGFITYRYTCDAFAALENGYTLRRSNETDFELYFCGRKQFFKSNYADLDSNSDDFDPASTKSKYDSLDFDSLLKEAQRSLRR
What is the function of this protein?
Transcriptional coactivator for steroid receptors and nuclear receptors.  Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter.  Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis.  Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism.  Acts as a key regulator of gluconeogenesis: stimulates hepatic gluconeogenesis by increasing the expression of gluconeogenic enzymes, and acting together with FOXO1 to promote the fasting gluconeogenic program (By similarity).  Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.  Also involved in the integration of the circadian rhythms and energy metabolism.  Required for oscillatory expression of clock genes, such as BMAL1 and NR1D1, through the coactivation of RORA and RORC, and metabolic genes, such as PDK4 and PEPCK (By similarity).
What are the official names of this protein?
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, PGC-1-alpha, PPAR-gamma coactivator 1-alpha, PPARGC-1-alpha.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body.