PharMolix/UniProtQA huggingface dataset:
Protein: RBFA_LATSS
Sequence: MKHRVGRVEQEIQREVNDILLKRVRDPRVEGVTITDINLSGDLQHVKVYYSILSNLASDAEKAQKGLDKAKGLIRSELGQRIKLYKIPEITFEQDGSVRYGEHIDELLRKLHQDEAQR
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_XANAC
Sequence: MAKIVVTGGQALHGEVHISGAKNAVLPILCATLLADAPVEISNVPHLHDVITTVKLLSELGAEVTIDEGTLAKGRSMLVDPRSVTHQVAPYELVKTMRASILVLGPLLARYGTAEVSLPGGCAIGSRPVDQHIKGLQALGADISVENGYIKATSNGRLKGARYVFDMVSVTGTENVLMAAVLAEGTTVLENAAMEPEVTDLADCLIALGARIEGAGTPRIVVQGVERLGGGHHAVLPDRIETGTFLVAAAMTGGSVTVRRARPETLDAVLDKLTEAGATITTTADSITLDMQGKRPRAVSLTTAPYPAFPTDMQAQFMALNCVADGVGVINETIFENRFMHVNELLRLGADIQVEGHTAIVRGAERLSGAPVMATDLRASASLILAGLVADGDTTIDRIYHLDRGYENIEEKLGALGATIQRTA
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPIC_SALTY
Sequence: MSEEGFMLAVLKGIPLIQDIRAEGNSRSWIMTIDGHPARGEIFSEAFSISLFLNDLESLPKPCLAYVTLLLAAHPDVHDYAIQLTADGGWLNGYYTTSSSSELIAIEIEKHLALTCILKNVIRNHHKLYSGGV
What is the function of this protein?
Virulence protein that plays a central role in mammalian macrophage infection, by inhibiting phagosome-lysosome fusion and cellular trafficking.  May act by disrupting the function of the mammalian HOOK3 protein, a protein involved in the cellular traffic.
What are the official names of this protein?
Salmonella pathogenicity island 2 protein C, Secretion system apparatus protein B.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Note=Translocated into the cytosol of macrophages via the Salmonella pathogenicity island 2 (SPI- 2) type III secretion system that functions intracellularly to translocate proteins across the phagosomal membrane. Cytoplasmic in infected macrophages.
Protein: ROSA_STRDJ
Sequence: MRPEPTEHPERTAAQRLYQYNVDLKVAFVLYAVAKLHLPDLLADGPRTTADLAAATGSDPSRLRRLLRAAAGADALREVPEDSFELAPMGDLLRSGHPRSMRGMTTFFAEPDVLAAYGDLVESVRTGVPAFQLRHREPLYDFLARPQHKEVRDEFDAAMVEFGQYFADDFLTSFDFGRFTRFADIGGGRGQFLAGVLTAVPSSTGVLVDGPAVAASAHKFLASQNLTERVEVRIGDFFDVLPTGCDAYVLRGVLEDWADADAVRLLVRIRQAMGDAPEARLLILDSVIGETGELGKVLDLDMLVLVEGEHRTRAQWDDLLARAGFDIVGIHPAGDVWAVIECRGTAG
What is the function of this protein?
Catalyzes the S-adenosyl methionine-dependent conversion of 8-amino-8-demethyl-D-riboflavin (AF) into 8-methylamino-8-demethyl-D-riboflavin (MAF) and roseoflavin (RoF), the last two steps in the biosynthesis of the antibiotic roseoflavin.
What are the official names of this protein?
8-amino-8-demethylriboflavin N,N-dimethyltransferase, AF dimethyltransferase, N,N-8-amino-8-demethyl-D-riboflavin dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.
Protein: RL332_LACLA
Sequence: MLRKAGLACTICGSRNYTLNLSSVAKEKRVEVKKFCRTCGKHTLHKETR
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RLMA2_STRFR
Sequence: MRKNVVRYLRCPHCAAPLRSSDRTLRCENGHTFDVARQGYVNLLRRPTKLAADTTDMVAARAALLDSGHYAPLTERLAGTARRAAGAGAPDCVVDIGGGTGHHLARVLEEFEDAEGLLLDMSKPAVRRAARAHPRASSAVADVWDTLPLRDGAAAMALNVFAPRNPPEIRRILRPGGTLLVVTPQQDHLAELVDALGLLRVRDHKEGRLAEQLAPHFEAVGQERLRTTLRLDHDALGRVVAMGPSSWHQDPDELARRIAELPGIHEVTLSVTFTVCRPLP
What is the function of this protein?
Specifically methylates the guanosine in position 748 of 23S rRNA.  Confers resistance to the macrolide antibiotic tylosine.
What are the official names of this protein?
23S rRNA (guanine(748)-N(1))-methyltransferase, 23S rRNA m1G748 methyltransferase, Tylosin-resistance methyltransferase RlmA(II).
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmA family.
Protein: NRDR_DESAH
Sequence: MKCPYCGQLNNRVVDSRLSRSEFAVRRRRECLDCMRRFTTYEKVEDLPVMVVKKDGRREEFNRDKILSGIKKACEKRAISVDQIEEVVDSVERDFRDANEKEISSTVVGNKVMELLHRLDDVAYVRFASVYREFKDVDDFIEELKSLIPRKILEDKKPDGCSDDG
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: THIG_BACCZ
Sequence: MIMLNIGPFSFHSRLLLGTGKFPDFDVQQKAIDVSEAEVLTFAVRRMDIFDAKQPNLLEKLDVKKYKLLPNTAGAKNAEEAVRIAKLAKASGLCDMIKVEVIGDDRTLLPDPVETLKASEMLLEEGFIVLPYTSDDVVLARKLQELGVHAIMPGASPIGSGLGIVNPLNLSFIIEQATVPVIVDAGIGSPADAAFAMELGADGVLLNTAVSGAKDPIKMAQAMKLSIEAGRLGFEAGRIARKRCATASSPLEGMSVVE
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ST7L_BOVIN
Sequence: MADGDGLGEAAIAAASPASAPGLSPSLGWRERLRAGLAGTGASLWFVAGLGLLYALRVPLRLCENLAAVTVFLNSLTPKFYVALTGTSSLISGLIFIFEWWYFHKHGTSFIEQVSVSHLRPLMGGTESSISEPGSPSNNRESETSRQNLSECKVWRNPLNLFRGAEYRRYTWVTGKEPLTYYDMNLSAQDHQTFFTCDTDFLRPSDTVMQKAWRERNPPARIKAAYQALELNNDCATAYVLLAEEEATTIVDAERLFKQALKAGETIYRRSQQCQHQSPQHEAQLRRDTNVLVYIKRRLAMCARKLGRIREAVKIMRDLMKEFPPLTMLNIHENLLESLLELQAYADVQAVLAKYDDISLPKSAAICYTAALLKTRTVSDKFSPETASRRGLSTAEINAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAIAYAFFHLQHWKRIEGALHLLQCTWEGTFRMIPYPLEKGHLFYPYPSCTETADRELLPSFHHVSVYPKKEIPFFIHFTAGLCSSTAMIAFLTHQFPEIMGVFAKAVSMISRTCIEYL
What are the official names of this protein?
Suppressor of tumorigenicity 7 protein-like.
What is the protein family that this protein belongs to?
Belongs to the ST7 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DUT_RAT
Sequence: MPLLCALLRSRLQPSLLRSLTLTSAQSLSCGGSRGVRTWSARTGPGACADPAVSVSKRARAEDDASLRFVRLSEHATAPTRGSARAAGYDLYSAYDYTIPSMEKALVKTDIQIAVPSGCYGRVAPRSGLAVKHFIDVGAGVIDEDYRGNVGVVLFNFGKEKFEVKKGDRIAQLICERILYPDLEEVQTLDNTERGSGGFGSTGKN
What is the function of this protein?
Catalyzes the cleavage of 2'-deoxyuridine 5'-triphosphate (dUTP) into 2'-deoxyuridine 5'-monophosphate (dUMP) and inorganic pyrophosphate and through its action efficiently prevents uracil misincorporation into DNA and at the same time provides dUMP, the substrate for de novo thymidylate biosynthesis (By similarity).  Inhibits peroxisome proliferator-activated receptor (PPAR) activity by binding of its N-terminal to PPAR, preventing the latter's dimerization with retinoid X receptor (PubMed:8910358).  Essential for embryonic development (By similarity).
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, PPAR-interacting protein 4, PIP4, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Binding to PPAR induces translocation to the nucleus.
Protein: AKTP1_DROER
Sequence: MTLDLDANKKDDKLLLTTIQQEYKILAEYKMIESEKLSGIYVIPSYANSLQWFGVFFGRQGFYTESVFRFTILLPDRFPDDKSLPTIIFQQDVIHPHVCPYTHGLDVSHAFPEWRCGEDHLWQLLKYLQTIFSDPLDSIRGIELDKLKDSEAAELLMTNKEEYVARVQKNIKESKEHIFDTPPTEDPHYIVFEKFQQDVHGPVLERIKAGRSKQTEPSAQQANGGHATGLSWVKEGEFKPLSIE
What are the official names of this protein?
Protein crossbronx.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. FTS subfamily.
Protein: RL6_DELAS
Sequence: MSRVAKTPVAIPAGVDVSIKDDQINVKGTGGALSQAQNALVKISNNEGKLSFEPVNDSREANAMSGTMRQLVNNMVVGVSKGFEKKLSLVGVGFKASASGSKLNLAIGFSHPVNFEMPAGITVTTPTPTEILVKGADRQAVGQMAAEIRAVRPPEPYKGKGIRYSDEKVVIKETKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: CTR1_ARATH
Sequence: MEMPGRRSNYTLLSQFSDDQVSVSVTGAPPPHYDSLSSENRSNHNSGNTGKAKAERGGFDWDPSGGGGGDHRLNNQPNRVGNNMYASSLGLQRQSSGSSFGESSLSGDYYMPTLSAAANEIESVGFPQDDGFRLGFGGGGGDLRIQMAADSAGGSSSGKSWAQQTEESYQLQLALALRLSSEATCADDPNFLDPVPDESALRTSPSSAETVSHRFWVNGCLSYYDKVPDGFYMMNGLDPYIWTLCIDLHESGRIPSIESLRAVDSGVDSSLEAIIVDRRSDPAFKELHNRVHDISCSCITTKEVVDQLAKLICNRMGGPVIMGEDELVPMWKECIDGLKEIFKVVVPIGSLSVGLCRHRALLFKVLADIIDLPCRIAKGCKYCNRDDAASCLVRFGLDREYLVDLVGKPGHLWEPDSLLNGPSSISISSPLRFPRPKPVEPAVDFRLLAKQYFSDSQSLNLVFDPASDDMGFSMFHRQYDNPGGENDALAENGGGSLPPSANMPPQNMMRASNQIEAAPMNAPPISQPVPNRANRELGLDGDDMDIPWCDLNIKEKIGAGSFGTVHRAEWHGSDVAVKILMEQDFHAERVNEFLREVAIMKRLRHPNIVLFMGAVTQPPNLSIVTEYLSRGSLYRLLHKSGAREQLDERRRLSMAYDVAKGMNYLHNRNPPIVHRDLKSPNLLVDKKYTVKVCDFGLSRLKASTFLSSKSAAGTPEWMAPEVLRDEPSNEKSDVYSFGVILWELATLQQPWGNLNPAQVVAAVGFKCKRLEIPRNLNPQVAAIIEGCWTNEPWKRPSFATIMDLLRPLIKSAVPPPNRSDL
What is the function of this protein?
Acts as a negative regulator in the ethylene response pathway (PubMed:8431946).  Phosphorylates the cytosolic C-terminal domain of EIN2, preventing the signaling in the absence of ethylene (PubMed:23132950).  Interacts with C24:1-ceramide upon hypoxic conditions (e. g.  submergences) to in turn regulate EIN2 endoplasmic reticulum (ER)-to-nucleus translocation and EIN3 stabilization (PubMed:25822663).
What are the official names of this protein?
Serine/threonine-protein kinase CTR1, Protein CONSTITUTIVE TRIPLE RESPONSE1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.
Protein: H2A_ASPNC
Sequence: MTGGKSGGKASGSKNAQSRSSKAGLAFPVGRVHRLLRKGNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGHVTIAQGGVLPNIHQNLLPKKTPKSGKGPGSQEL
What is the function of this protein?
Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: EX7L_COREF
Sequence: MPSAKSTPDTPWPVRDVNNQVKNWIERLGHLWVEGQLAQINVKPNWKLSYLTLRDVEQEVSVQLTCPTEIIRNRPTPLKDGDRVIVYGKPAFYAGRGSFSLWVTDIRPVGIGQLLARIEELRRQLAAEGLFDPARKKRLPFLPKCVGLITGRGSAAERDVLSVARDRWPEVQFKVINTAVQGASAVPEIIAALGELDQDPGVDVIIIARGGGSVEDLLPFSEEALQRAVAAAQTPVVSAIGHEPDTPILDNVADLRAATPTDAAKRVVPDVNEERLLIRQLRDRGAAALRGWVAREQQALASIRTRPVLADPMTPIVRRREEVERAVSLLRRDVNHMLRTEQSLVASLRAQVSALGPSATLARGYSVVQVVPRDGTPPQVVTTIEQTPPGSQLRIRVADGAITAAAMNTQKSD
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_THEYD
Sequence: MPSVNVRDMDSFEAALKMFKKQCEREGILSEIKKREHYEKPSVKRKKKVLAARKKLAKKMKMLSR
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: S2551_RAT
Sequence: MMGSEAHDKRPPMLTSSNQDLSPHLADVGQIKHYFCGCCAAFNNVAITYPVQKILFRQQLYGIKTRDAILQLRKDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSRLLRKHVSNAPEFATRSVAALLAGTTEAILTPLERVQTLLQDHKHHDKFTNTYQAFRALRCHGVAEYYRGLVPILFRNGFSNILFFGLRGPIKEHLPTATTNSEHLVNDFICGGVLGAMLGFLSFPVNVVKARIQSQIGGPFQSLPMVFKTIWIERDRKLINLFRGAHLNYHRSLISWGIINATYEFLLKIV
What is the function of this protein?
Mitochondrial membrane carrier protein that mediates the import of NAD(+) into mitochondria.  Mitochondrial NAD(+) is required for glycolysis and mitochondrial respiration.  Compared to SLC25A52, SLC25A51-mediated transport is essential for the import of NAD(+) in mitochondria.
What are the official names of this protein?
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51, Mitochondrial NAD(+) transporter SLC25A51, Mitochondrial carrier triple repeat protein 1, Solute carrier family 25 member 51.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MFTB_MYCS2
Sequence: MSTQVAEQITFDPDVSWRLHHQVAVRPEPFGALLYHFGTRKLSFLKNRTVVEVVNSLADHPDARSALCAAGVADDQQAPYLHALGVLVQSNMLVPGNPEGSQ
What is the function of this protein?
Peptide chaperone involved in the biosynthesis of the enzyme cofactor mycofactocin (MFT).  Binds MftA and MftC with high affinity, and is essential for MftC activity on MftA, likely via the formation of a ternary complex (PubMed:27158836) (By similarity).  Is required for the in vivo ethanol assimilation in M. smegmatis (PubMed:31113891).
What are the official names of this protein?
Peptide chaperone MftB.
What is the protein family that this protein belongs to?
Belongs to the peptide chaperone MftB family.
Protein: MTNN_SODGM
Sequence: MKIGIIGAMEQEVALLRDRIDHSTLCQQAGCEIYMGQLHGVEVALVKSGIGKVSAALGTTLLLDHFKPELVINTGSAGGLAPSLKVGDIVVSHEVRYHDVDVTAFGYEPGQMAQCPASFNAAPSLVALAEESVDRLGMHAVRGLVVSGDAFINDADGLAHIRQTFPQAIAVEMEATAIAHVCHQFAVPFVVVRAISDVADQASHLSFDEFLTVAAQSSSRLVEEMVQALAGQR
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.  Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: RL30_TREPS
Sequence: MTKRVRITLVRSTIGQREPVRRTVRSLGLRKLHSMVEKDGSPAVLGMVRAVSHLVRVEELG
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: FLBA_CAUVC
Sequence: MSRKSALESSASVLAQADVGASGIHPSVIADAMGDSASAEALERLNRAAQDTKNVDNAKHLARAIQAVQLQDYAKADKLALKLLEKDERLGLAWHILAIAREKTGDFASSLRAYEAALALLPDHGPVAGDLGRLAFRMNMPELAAKFFAHYRLARPDDVEGANNLACALRELNRESEAIEVLKAALGANPEAAVLWNTLGTVLCNIGDAAGSIVFFDESLRLAPDFSKAYHNRAFARLDLGEIEAALADCEAAMRSPGSPEDLAMMQFARATILLALGRVGEGWEAYESRFSPALSDAPRFQIPGVRWSGQDLRGKRLMITTEQGLGDEVMFANMLPDIVEALGPDGFLSLAVERRLAPLFERTFPKVEVTAHRTIAYEGRVFRAAPYIENWDRFDYWAAIGDFLPSLRPTAEAFPKRNAFLQPDPARVAHWKAQLEKLGPGPKVGLLWKSLKLNAERARQFSPFHLWEPVLHTPGVVFVNLQYGDCEEEIAFAKEELGVEIWQPEGIDLKADLDDVAALCAAVDLVIGFSNATINLAGAVGTPIFMLTGASSWTRLGTEYYPWYPSVRCFVTEQYGVWEPTMGRVATALRDFAAS
What are the official names of this protein?
Protein FlbA.
Protein: SYE2_CALS4
Sequence: MKEFRVRFAPSPTGPIHIGNMRTALFNYLFSRSEGATFVLRIEDTDLERSSKGFEELIFKELKWLGIEWDEGPDKPGPYGPYRQSERLEIYHRFAQKLIEEKKAYRCYCTPEELEEDRKKAIERGEIPRYSGRCRYLTKEQEETFIREGRKPVIRFMVPDDEVIEFEDMIKGKITIKSDTLGGDMVIIKSDGMPTYNFAVVIDDALMKITHVIRGEDHIYNTPKQILIYKALGFEIPKFAHVPLILGPDRTKLSKRHGHTYIGQYRELGYLPEAMFNFLSLLSWYPEDNVELMSKEEIIRKFNFKRIHKSNPVFDIEKLNWMNQQYIQKSPVERIVDLAIPHLKKAGYIDEIDELRYNWLKDVISLYKDGLSYVAQIVDMAKTFFVEEVDYTGEMIEFLKSPNSIKVLEAFKGYLKDKSEITEDDVREWMKKAQKELGVKGKEFFMPIRIAVTGEEHGPELVKVLALLGKNRVVKRLDRVLNLIE
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL16_ARATH
Sequence: MHAIFCRRVAVGCSSPQLTKLVTKQASQSRHSLSHLLPFDLSSRFVPPYVVSRSARVHGFFAGKLGNTNLKLKFGNVMESRAGFFSSELPSHGFESGGFTGFQKRGWKSWINGANGVVFGLVIANAAVFTMWRVLGKDNMWMVKNFMLSRYSFMTGRIHTLITSGFSHVGATHIILNMMGLCYFGARIARSFGPRYLLKLYFAGALGGSVFFLSSHALSVISLKGQRVVPKDQLKVPIGKLGANGPVYAITLLDMLLYPKVTTYFGLMLRVPVFAGIYSLGLNIIKMLEGKNNNTLTSLDQLGGVVVAVIAWARIRKGRFCY
What is the function of this protein?
Rhomboid-type serine protease that catalyzes intramembrane proteolysis.  May cleave the plastid translocon component Tic40.
What are the official names of this protein?
Rhomboid-like protein 16, chloroplastic, AtRBL16.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: RS15_CUPPJ
Sequence: MAVADINKSEVIKQFARGTNDTGSPEVQVALLTTRINELTPHFKANMKDHHSRRGLLRMVSRRRRLLDYLKSNDADRYRALIEKLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: LKHA4_SCLS1
Sequence: MPRDPNTLSNYNNWRTKHTIADLAIDFKKQRVHGTVTLQLESITDKESEEIILDTSFVDVQKIAVDGSKTEEWVLKERNEPYGSPLSVKIPGGAAKGTIIALDITISTTDKCTALQWLTPAQTSNKKFPYMFSQCQAIHNRSIFPCQDTPDVKSTYDFRIRSPLPVLASGLPRGAASFVHGENGESGTLLYSFYQEIPMPSYLFALSSGDIATASIGSRSLVSTGPEELLGAKWELERDTEKFIETIEKIVYPYEWTQYNVLVLPPSFPYGGMENPVFTFATPTIISGDRENVDVIAHELAHSWSGNLVSNASWEHFWLNEGWTVYLERRIIAAVHGEAYRDFSSIIGWKALEDSVKLFGEDHEFTKLVVDLKGKDPDDAFSSVPYEKGFHFLYYLERLVGKPTWDKFIPHYFTTWKKKSLDSYEFKATLLDFFASDEAASKALESVDWDSWFYKPGLPPKPEFDTSLVDKCYALAKKWESKDFVPSPSDIEGWSANQVVVFLQQVQLFTTPLTPSQSQAMGKAYSLVDTQNVELSSRYFGVGLAAKDESVYLPTAELLGKVGRMKFVRTLYRKLLVVDRKLAEETFEKNKDFYHPICREQVEKDLKE
What is the function of this protein?
Aminopeptidase that preferentially cleaves di- and tripeptides.  Also has low epoxide hydrolase activity (in vitro).  Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro).
What are the official names of this protein?
Leucine aminopeptidase 2, Epoxide hydrolase, Leukotriene A-4 hydrolase homolog, LTA-4 hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PLA1_CAEEL
Sequence: MSGSEEEHLVSLTFRKNEEDMDEDEGKVKQKEKPKEKQMEFVNQNFVESTEDESEVSTPTAVGLPIGTSTPDGDETPTQPDPNGKYTMAQTKDADLSRPSGLPSNGNPGSSTTVPPASKSGPVAPPRPSGTPVAPQRNRRRKVTELKCSEVRWFFQEPKGTLWNPFNGRDSIMLEIKYRKEKGIELDEAMQEIYDESLTHYKMEMKDEPEIENGNIGMEQEKPMVVVMNGQYKVNKDNSKIDPIYWKDDSKEIRRGSWFSPDYQPLEMPLSDQIEKNHLQCFRNQMIPEGTTVFSKSETSNKPVLAELHVDGYDIRWSSVIDISLHQKGNAILRYLWAKSTPLRRGYEKEADWNDAAAEISHLILVVHGIGQKGYENLIAQNANQVRDGVVSAMEKVYPEEKSRPMFLPVEWRSALKLDNGLTDNITIPKMSSMRASLNSTAMDVMYYQSPLFRTEIVRGVVSQLNRTYKLFKANNPQFNGHVSVFGHSLGSVICYDVLTQYSPLMLFDKYVTKSIDEYLKRDDTNASEEARKALEAMKLAREQLRDNLEGGIHKLLVTKEEQLEFKVKYLFAVGSPLGVFLTMRGGESTDLLSKATNVERVFNIFHPYDPVAYRLEPFFAPEYRHIRPIKLFSNTDLRARASYENLPLDVYKHYLKKLKNLNKAKKNKDDKTADARSGGDDENEDEDECDSDEDARSGCSSPRSMTPPPFETAAANAAAAAKETKAVKKGWFSFGTSSNPKKTQSTASLGSVNATSTENIEFAKEAAEELPLAEKILGSGVRVPHRIDFQLQPALTEKSYWSVLKSHFAYWTNADLALFLANVLYCKPLKPEEAKPTWA
What is the function of this protein?
Hydrolyzes the ester bond at the sn-1 position of glycerophospholipids and produces 2-acyl lysophospholipids, being phosphatidylinositol (PI) its major substrate.  PI is a versatile lipid that not only serves as a structural component of cellular membranes, but also plays important roles in signal transduction through distinct phosphorylated derivatives of the inositol head group (PubMed:20668164).  Catalyzes the hydrolysis of phosphatidylcholine at sn-2 position in vitro (PubMed:23007400).  Regulates asymmetric division, an important property of stem cells in C. elegans, by controlling the subcellular localizations of beta-catenin (PubMed:18497747, PubMed:20668164).
What are the official names of this protein?
Intracellular phospholipase A1, IPLA-1, PLA(1).
What is the protein family that this protein belongs to?
Belongs to the PA-PLA1 family.
Protein: KAD_MYCLB
Sequence: MRVVLLGPPGAGKGTQAQRLAEKLGIPQISTGELFRRNIEKDTKLGHEAKKYLDAGDLVPADLTNQLVDDRLNKSDTVDGFILDGYPRSLEQAKALHEMLERRGTDIDAVLEFRVSQAVVLERLKGRGRADDTDDVVINRMNIYRDETASLLEYYSSELKTIDAIGTMDEVFARALHALGK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BLT4_HORVU
Sequence: MARTAATKLALVPLVAAMLLVAADAHHLRPGELCLGPLRRLRKRQRHQPSAGCCSGVKRLAGLARSTADKQATCRCLKSVPARTTPAGPQASPPGAASASPTRSAPVSTALRSTDRTRAPHISSDRRLVG
What is the function of this protein?
Possible dehydrative stress responsive protein.  Not shown to have lipid transfer activity.
What are the official names of this protein?
Protein BLT4.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: EXGA_ASPFU
Sequence: MIFKFSQKALVALYLVVGLAEAVPSKSRVVSRASTFDYNGIVRGVNIGGWLVLEPWITPSIFDNAGDAAVDEWTLTATLGQDQAKAVLSQHWSTFITQDDFQQIAQAGMNHVRIPIGYWAVSSLPDEPYVDGQLEYLDNAISWAREAGLKVVIDLHGAPGSQNGFDNSGRKGPIAWQQGDTVSQTVDAFRALAERYLPQSDVVTAIEALNEPNIPGGVSEAGLRDYYNQIADVVRQIDPGTSVFLSDGFLSTESWNGFKTGEDVVMDTHHYEMFDNYLISLDIDGHVKSACDFGKQIEGSDKPVVVGEWSGAVTDCTKHLNGKGVSTRYQGEYANNVKYGDCANTTQGSVADLSDQERTDTRRFIEAQLDAYEGKNGWLFWTWKTEGAPGWDMQDLLANGVFPSPLTDRQFPNQCA
What is the function of this protein?
Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall.  It could also function biosynthetically as a transglycosylase (By similarity).
What are the official names of this protein?
Probable glucan 1,3-beta-glucosidase A, Exo-1,3-beta-glucanase 1, Exo-1,3-beta-glucanase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.