PharMolix/UniProtQA huggingface dataset:
Protein: LKHA4_ASPCL
Sequence: MATVINPPRDPNTLSNYNNWVSIHITANFDILFDQKKLAGNVVHRFRSTTRGESRDIILDTNHLDIGGVKVNGQPSSWEFLPRLEPYGTPLKIKLDQAVELDETIEVDISVTTTEKCTALQWLTPAQTSNKKHPYMFSQCQAIHARSIFPCQDTPDVKCTLDFNITSPLPVIASGLPVRKQPETSKSEGKSLYQFHQKVPIPSYLFALASGDISEASIGPRSVVATSPDKLRECQWELEADTEKFINAIEKIVYPYVWGEYNVLILPPSFPYGGMENPIFTFATPSIISKDRENIDVIAHELAHSWSGNLVTNASWEHFWLNEGWTTYLERRVSDASVHGEPYRHFSAIIGWKALTDSMDHFGHDHDFTKLITNLKGKDPDDAFSSIPYEKGFNFLYYLETLVGKSKFDDFIPHYFNKFKGKSLDSYEFKATILDFFQADSEAAKALNEVDWDKWFYAPGLPPKPDFDTSLVDVVYDLAKKWLSLPGSSFKPQPNDIRGLSANQIVVFLEQVLVSEHQLTPELSRLMGEVYGLARSNNIEVANLYCQVGMKAGDESVLEPTIELLGKIGRMKFVRPLYRNLQKFNRQRAIETFQEYKDFYHPICRAMVEKDLFGKKEE
What is the function of this protein?
Aminopeptidase that preferentially cleaves di- and tripeptides.  Also has low epoxide hydrolase activity (in vitro).  Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro).
What are the official names of this protein?
Leucine aminopeptidase 2, Epoxide hydrolase, Leukotriene A-4 hydrolase homolog, LTA-4 hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GLSA_MARMS
Sequence: MEDLLHSIEQKVKPLIGLGKVADYIPALANVDPNQFGIAIYSNNGELYHAGQAYTDFSIQSISKVFSLTLAIKHYGEDMWKRVGREPSGNPFNSLVQLEYEAGVPRNPFINAGALVISDMNQSRFASPHYAMREFIRRLADNPHLNSDQIVANSEYEFRARNASMAYLMKAFGNFENDVEDVLHSYFDNCAMRMNCVDLAKSFSFLANKGYSQLSGEQILSARETTQVNGLLATSGLYDEAGNFAYRVGLPGKSGVGGGIIAIVPNRFSVCVWSPELNKSGNSLAGMAALEALSESIGWSVFG
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: WUN_DROME
Sequence: MPAVKIIMSTETSASETTPLRRSENETPDHKELAQSNSNSRQTTVNSNNNNYSNSVQVRLQEQDRDSDSEQQQHTATITMDTNKRILCRVGLDVLILLCAGFPILLFFLLGEPYKRGFFCDDESLKHPFHDSTVRNWMLYFIGAVIPVGVIFIVEVIISQNKAKQDNGNATSRRYVFMNYELPDWMIECYKKIGIYAFGAVLSQLTTDIAKYSIGRLRPHFIAVCQPQMADGSTCDDAINAGKYIQEFTCKGVGSSARMLKEMRLSFPSGHSSFTFFAMVYLALYLQARMTWRGSKLLRHLLQFLFIMVAWYTALSRVSDYKHHWSDVLAGSLIGSISALVVANYVSDLFQKPNTKPYLARTVQDMNASPAQAITITTN
What is the function of this protein?
Responsible for guiding the germ cells early in the process of migration from the lumen of the developing gut towards the overlying mesoderm, where the germ cells enter the gonads.  May be involved in lipid metabolism.
What are the official names of this protein?
Putative phosphatidate phosphatase, Germ cell guidance factor, Phosphatidic acid phosphatase type 2, Protein wunen.
What is the protein family that this protein belongs to?
Belongs to the PA-phosphatase related phosphoesterase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FETP_PSEA6
Sequence: MSRTVFCQHLNKEADGLDFQLYPGELGKKIFDNISKEAWTEWQKKQTMLINEKKLNMMEPTARNFLETQMQAYLFEGKEPDIEGYVPPKS
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: PIP_LACDL
Sequence: MQITEKYLPFGNWQTYCRIVGEATDRAPLLLLHGGPGSSHNYFEVLDQVAEKSGRQVIMYDQLGCGNSSIPDDQAETAYTAQTWVKELENVREQLGLDQIHLLGQSWGGMLALIYLCDYQPKGVKSLILSSTLASAKLWSQELHRLIKYLPKGEQAAIKEAETTGNYDSPAYQAANAHFMDQHAINVTPDLPEPVLRKKKGGNLAYLTGWGPNEYTPIGNLHGYEYTDRLKDLDLPALITSGTDDLCTPLVAKSMYDHLPNARWELFAGCGHMPFVQENAKYQELLSDWLISQD
What is the function of this protein?
Releases the N-terminal proline from various substrates.  Cleaves Pro-betaNA (L-prolyl-beta-naphthylamide) effectively.
What are the official names of this protein?
Proline iminopeptidase, PIP, Prolyl aminopeptidase, PAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S33 family.
What are the subcellular locations of this protein?
Cell envelope.
Protein: RS9_MARSD
Sequence: MSKDFNYATGRRKNAVARTRLYEGTGAITVNGKPYEDYFPRKTLQMIVQQPLKLTKTLGKFDIKVNADGGGVAGQAQAVRHGISRALIEIDPELRSILKRAGLLTRDARKKERKKYGQPGARAKFQYSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RNZ_MYCMM
Sequence: MIEITLLGTGSPIPDPDRAGPSTLVRAGGQVFLVDCGRGVLQRAAAVGVGAAGLSAVLLTHLHSDHIAELGDVLITSWVTNFAADPAPLQVIGPPGTAETVDAMLKAFGRDIGYRIAHHADLNAPPPIEVHEYTDGTVWDRDGVAIRVAPTDHRPVAPTIGFRVEFDGASAVLAGDTVPCPSLDELAAGAGALVHTVIRKDIITNFPQQRVKDICDYHSSVQEAAATAARAGVGTLVMTHYVPAIIAGQEDQWRALAATEFGGRIELGNDLHRVEVHAR
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: VE4_HPV33
Sequence: MADPEATKYPLLKLLTYRQTTITDHHKQRPNDDDLQTPQTPPSPLQSCSVQTPPWTIEQHVLQLTAQTSSGLCVVLTLHL
What is the function of this protein?
Contributes to multiple aspects of the viral life cycle including viral genome amplification, suppression of suprabasal cell differentiation and egress of newly formed virions.  Induces host cell cycle arrest at the G2 phase by associating with and preventing the nuclear entry of host CDK1/cyclin B1 complexes.  Inhibits cellular DNA replication by preventing loading of host replication licensing proteins MCM2 and MCM7 onto chromatin.  Within the cytoplasm, associates with host kinase SRPK1, a splicing factor regulator, and inhibits its activity.  Therefore, E4 favors expression of late viral transcripts by inhibiting SRPK1-mediated phosphorylation of host serine-arginine (SR) proteins that have critical roles in mRNA metabolism.  Late in the infectious cycle, E4 also acts to diminish the integrity of the keratinocyte by disrupting the keratin cytoskeleton and inducing apoptosis through alteration of mitochondrial function to facilitate egress of the newly formed virions.
What are the official names of this protein?
Protein E4, E1^E4.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E4 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: TILS_XANCP
Sequence: MDVMQAAGLIPATPPAPVLVAYSGGMDSAVLLHALAATDGYREAGLRAVHVHHGLHADADAWALHCQQQCADLGIALQVVRVQVARDSGSGLEAAARAARHAAFAATLAAGEWLALAHHRDDQAETFLLRALRASGPDGLAAMRPQRPFGPGTLWRPLLGHARADLAAYAQAHAVRWIDDPSNTDPQHERNFLRTQVLPALQQRWPLAADALARSAQLCGDASTLLHDDDVNLLPTVCNSAGALELQPLRSHSPARRARLLRAWVAAAHAPPLPAQGVHALEREIATTQPDRQTCFAWQQTEIRRWRQQLYLLSARATWPAQWQAEWNGDSTLLLPDGAQLQLRGTPGLRFEQPLQVRARQGGERIVLPGRTHSHQLKHLLQQSDLPPWERTRLPLLWAGKTLLAAGDQIVSAKLDQWLRAHAARLQWRSAAPAN
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODL_VACCC
Sequence: MAVCIIDHDNIRGVIYFEPVHGKDKVLGSVIGLKSGTYSLIIHRYGDISQGCDSIGSPEIFIGNIFVNRYGVAYVYLDTDVNIFTIIGKALSISKNDQRLACEVIGISYINEKIIHFLTINENGV
What is the function of this protein?
Superoxide dismutase-like protein with no enzymatic activity.
What are the official names of this protein?
Cu-Zn superoxide dismutase-like protein OPG175.
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Accumulates predominantly in cytoplasmic viral factories.
Protein: RL2_SYNS9
Sequence: MAIRKFRPYTPGTRTRVVTDFSEVTGRKPEKTLVVSKHRKKGRNNRGVITCRHRGGGHKRLYRLVDFRRNKHGVTAKVAAIHYDPHRNARLALLFYSDGEKRYILAPAGVQVGQTVVSGPEVPIENGNAMPLSSVPLGSSVHCVELYAGRGGQMVRTAGASAQVMAKEGDYVALKLPSTEVRLVRRECYATLGEVGNSEVRNTSLGKAGRRRWLGRRPQVRGSVMNPCDHPHGGGEGRAPIGRSGPVTPWGKPALGLKTRKRNKPSNQYVLRKRRKTSKRSRGGRDS
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: UBC2_EMENI
Sequence: MSTSARRRLMRDFKRMQTDPPAGVSASPVADNVMTWNAVIIGPADTPFEDGTFRLVMHFEEQYPNKPPGVKFISQMFHPNVYGTGELCLDILQNRWSPTYDVAAILTSIQSLLNDPNTSSPANVEASNLYRDNRKEYIKRVRETVEKSWEE
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.  Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1.  H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation.  Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 2, E2 ubiquitin-conjugating enzyme 2, UV sensitivity protein J, Ubiquitin carrier protein ubc2, Ubiquitin-protein ligase ubc2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TAZ_DICDI
Sequence: MDSNNSNNNNKNLKQICDIPKPQFLSKGVFTLVGVLCKFWISMNTVTTSGIDKLVNEIDKTHQLKRPMITIANHSSNLDDPLLWGVLPNRILMDPSKQRWTLGASNILFTNWFYSKFFSLGKCIKIVRGDGIYQDGMNESIDRLSEGQWLHIFPEGRISQQTQLLYFKWGLGRLVGECYRRTGVVPLVVPIYHQGMEKSMPLAKLPIPRVGINLDIKVGDNIYCDQVISKYIDDNKISDLTDYLSQDDKKRKDFYKTITLHIEDEYQKIIPPTNRGRFSHPTIKD
What is the function of this protein?
Acyltransferase required to remodel newly synthesized phospholipid cardiolipin (1',3'-bis-[1,2-diacyl-sn-glycero-3-phospho]-glycerol or CL), a key component of the mitochondrial inner membrane, with tissue specific acyl chains necessary for adequate mitochondrial function (By similarity).  Its role in cellular physiology is to improve mitochondrial performance (By similarity).  CL is critical for the coassembly of lipids and proteins in mitochondrial membranes, for instance, remodeling of the acyl groups of CL in the mitochondrial inner membrane affects the assembly and stability of respiratory chain complex IV and its supercomplex forms (By similarity).  Catalyzes the transacylacion between phospholipids and lysophospholipids, with the highest rate being between phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) and CL.  Catalyzes both 1-acyl-sn-glycero-3-phosphocholine (lysophosphatidylcholine or LPC) reacylation and PC-CL transacylation, that means, it exchanges acyl groups between CL and PC by a combination of forward and reverse transacylations.  Also catalyzes transacylations between other phospholipids such as phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine or PE) and CL, between PC and PE, and between PC and phosphatidate (1,2-diacyl-sn-glycero-3-phosphate or PA), although at lower rate.  Not regiospecific, it transfers acyl groups into any of the sn-1 and sn-2 positions of the monolysocardiolipin (MLCL), which is an important prerequisite for uniformity and symmetry in CL acyl distribution.  Cannot transacylate dilysocardiolipin (DLCL), thus, the role of MLCL is limited to that of an acyl acceptor.  CoA-independent, it can reshuffle molecular species within a single phospholipid class.  Redistributes fatty acids between MLCL, CL, and other lipids, which prolongs the half-life of CL.  Its action is completely reversible, which allows for cyclic changes, such as fission and fusion or bending and flattening of the membrane.  Hence, by contributing to the flexibility of the lipid composition, it plays an important role in the dynamics of mitochondria membranes (By similarity).
What are the official names of this protein?
Taffazin, Taz, 1-acylglycerophosphocholine O-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the taffazin family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Intermembrane side. Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: NHAA_HAEIN
Sequence: MNFLLCIFKGVYVIKLIQRFFKLESAGGILLLFSAVVAMLLANSPLSNQYNDFLNLPVSLQIGSFSINKTLIHWINDGFMAVFFVLVGMEVKKELFEGALSTYQQAIFPAIAAIGGMVIPAVVYWFIAKQDPSLANGWAIPMATDIAFALGIMALLSKQVPLPLKIFLLALAIIDDLGAIVVIALFFSHGLSVQALIFSAVAIIVLILLNRFRVSALCAYMVVGAILWASVLKSGVHATLAGVIIGFSIPLKGKKGERPLDDFEHILASWSSFVILPLFAFANAGVSFAGIDVNMISSPLLLAIASGLIIGKPVGIFGFSYISVKLGLAKLPDGINFKQIFAVAVLCGIGFTMSMFLASLAFDANAGESVNTLSRLGILLGSTVSAILGYLFLKQTTKLN
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y990_SHESA
Sequence: MLNTKFDELMEFPCAFPFKVVGDAHEALTDRVVAVVQRHAPGDYSPTVKASSKGSYYSVTIRVTVTSKDHIETLYTELAGIEGVRRVL
What are the official names of this protein?
UPF0250 protein Shewana3_0990.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: Y1130_PARD8
Sequence: MDTIIKTQIIDLIHREVIPAIGCTEPIAVALAAAKAAEVLGRKPEKIEVYLSANILKNAMGVGIPGTGMVGLPIAIALGSIIGKSAYGLEVLKDLTSEGLKEGKEMVCKKCIGIDLKENVDKLYIEIISSAGNDRSRVIICHEHTHIIYVEKNGEVLTDLRTANASGEEVCENKDLRLSFSMVYEFAMEMPLDEIRFILETAELNKKAAQASMKGNYGHTVSKTVSGAFGRKFMGDSAYTHMLIMTSAACDARMDGAMIPVMSNSGSGNQGIAATLPVLSFAEDIQCSEEQLIRALMLSHLMVIYIKQSLGRLSALCGCVVAATGASCAITYLMGGNKARISYAIKNMIGNITGMICDGAKPSCAMKVSSGVSTAMLSALMAMEDKVVTSVEGIIDEDVDKSIANLTAIGSKGMEATDRLVLDIMTGKSC
What are the official names of this protein?
UPF0597 protein BDI_1130.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: M1_I49A1
Sequence: MSLLTEVETYVLSIVPSGPLKAEIARRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLYRKLKREITFHGAKEVALSYSTGALASCMGLIYNRMGTVTTEVAFGLVCATCEQIADSQHRSHRQMVTTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMRTIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: HIS7_BURP6
Sequence: MRVAQVVRNTSETQISVKIDLDGTGRQKLATGVPFLDHMLDQIARHGLVDLDIEAHGDTHIDDHHTVEDVGITLGQAVAKAVGDRKGIRRYGHSYVPLDEALSRVVIDFSGRPGLEFHVPFTRARIGTFDVDLSIEFFRGFVNHAGVTLHIDNLRGVNAHHQLETVFKAFGRALRMAVELDERAAGQIPSTKGSL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCPP_YERPP
Sequence: MYHVIAATTNPAKINAITLAFDDVYGPGQYRIEGVNVDSGVPLQPIGSTETRIGARQRVKNARQVRPEADFWVGIEAGIEDNMTFAWMVVEHLQARGESRSASLMLPDIILQGIRQGRELGDEMAVLSGISNVKQQGGAIGIFTQGKLTRTSVYHQALLLALVPFHNEIYQRPSPSKPAI
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: Y1351_SYNJB
Sequence: MLLTTTDVLQGREVERYLGIVTAEVVYGTNVLRDFLATLRNIIGGRTRTYEEVFENAQKKVLEELEQRAKRLGANGILGVSIHTNMSTTMILVTAAGTAVKLR
What are the official names of this protein?
UPF0145 protein CYB_1351.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: TRMN6_SHELP
Sequence: MPFTFKQFHVDDSHCGMPVSTDGVLLGAWAPLTQAKTILDIGAGSGLLSLMAAQRSEAVIQALEIDPLAAQDCQHNIDQSPWSDRITLIQADLLQWYPLAQTQAQTQFDHILCNPPYFDNGPQSQCSKRAQARHTDSLAFDQLLSAIKQLLAPTGKASLILPNASLGRFLPLLAEFKLKLSARVDITTAPNKAPQRHLLCLSHAVSSAESSEAIEAEHLSIRDASGAYSQAMVALTQAFYLKL
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURL_LEPIC
Sequence: MEKDVVSLEDALEHGLTKEEFQKIQEILGRIPNSTELGIFSAMWSEHCSYKNSILKLKTLPTTSDKLLAKAGEENAGAMDIGDGLAVVFKIESHNHPTAVEPYQGAATGVGGIMRDIFTMGARPIVSLNSLRFGNPDEPKNKYLLSRAVKGIGDYGNSLGIAVSGGELFIDECFSKNPLVNAMTVGVVRHDQMASATTGGQVGNSVYIVGATTGRDGIHGASFASKDLSKESESKRSAVQVGDPFMEKLLMEASLEAIQKGLLVGIQDMGAAGISCATSEMSAKGKTGMKIDLDLVPFRETGMNAYEAMLSESQERMLVVPKKGKESELVSIFEKWNLNAVKIGEVTADGMIEIYMGGKLKAKIPAESLVLGGGAPRYERETKRPSYLDAVKTWKPDEIPDVTKGANSKEILLKILSSWNVCSRKPITEQYDSEVGLVKLIGPGLDGGLSAIPGTNKALATATDCNSRYTYLDPYKGAEFAVCEAARNVYVTGATPYGVTNNLNFANPYIPENYYIFSECIRGMGDACRFLGLPVTGGNVSFYNESPEGPIFPTPTIGMVGILENKEKLIFNFPKEIGVELAVLGNFRPSLGGSEYLKKIHGQINGSIPELDIKEELELCKLILSLNESRILKSAKDLSLGGIAVALSKTVLFSGLGIESDLTSLRRNRLDLTLFGESSTAVLVGFDSLSKEDIRKQTEAYGLKFYPIGKTNSSGILEIKDAEIKISFQELSGPYEKGLEAVFAL
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MLTF_SHEHH
Sequence: MKKLLLILCCITLLAACQKVVVEQEEPVFIPEPTELVVGTLYGPQIYFTSGQGDSGYDYEMAERFAKYLNLKLKMRAFANISELYAAMRSGEIDIIAAGLGDTPARREQFRVGPPLYRVDQVLVYRQGTPVPKNINSLNGEITVITDSSFVDTLTDLQKSNPDLVWNQEKDKDAEELLTMIAAGDIPYTIADSTSLDINRRFMPELREGLVLKKKQPVVWLLPANNSDKLMSQLLAFWHIEKRSGTLAHLNEKYFAHVKRFDYVDTRAFIRAIDNKLPKYQSTFEKYAGDIDWRKLAATAYQESHWNPNARSPTGVRGLMMLTLPTAKQVGIKNRLDPYQSIQGGAKYLNSMLERLPESIPDSQRMWFALASYNIGLGHVEDARKLAQTQGLNPSAWRDVKSVLPLLQKRKYYKKTRYGYARGNEAVHYVDSIRRYYDTLVWIDNQNMLLELKKENIQMAENLEQKTEAAQPQQP
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: GATC_STAHJ
Sequence: MTKVTREEVEHIAHLARLQISEEETEEMANTLESILDFAKQNDTADTEGIEPTYHVLDLQNVLRDDEAIEGIPQELALKNAKETENGQFKVPAIMNEEEA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: QUEA_PSEPW
Sequence: MRVADFSFELPDSLIARHPLAERHGSRLLVLDGPSGALAHKQFTDLLDYLRPGDLMVFNNTRVIPARLFGQKASGGKLEVLVERVLDSHRVLAHVRASKAPKEGAVILIDGGGEAEMVARHDTLFELRFTEEVLPLLERVGHMPLPPYIDRPDDGADRERYQTVYAERAGAVAAPTAGLHFDQALLDKIAAKGVERAFVTLHVGAGTFQPVRVDKIEDHHMHKEWLEVSQDVVDAIEACRARGGRVVAVGTTSVRSLESAARDGVLKAFSGDTDIFIYPGRPFHVVDALVTNFHLPESTLLMLVSAFAGYPETMAAYAAAVEQGYRFFSYGDAMFITRNPAPRGPEDQA
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR4_NEPOL
Sequence: MSRYRGPRLKIVRRLGELPGLTRKMAKRKSPPGQHGAASKKPSQYRIRLEEKQKLRYNYGVTEKQLLRYMQRARRAKGSSGENLLQLLEMRLDTTIFRLGMAPTMLSARQLITHGHILVSEQRVNIPSYQCSPKEKISIRSNSRSRKLIEGYMSTMGSIVTPPHLELKKEKLEGNIQEIIDRQWVGLPINELLVVEYYSPKV
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRP1_PYRAP
Sequence: GPSGFLGMR
What are the official names of this protein?
Tachykinin-related peptide 1, TKRP-1.
What are the subcellular locations of this protein?
Secreted.