PharMolix/UniProtQA huggingface dataset:
Protein: MIAB_LEPCP
Sequence: MHTPTLTSTPTTATSVVDDTAPAASGKKVYIRTFGCQMNEYDSDKMSDVMAAAEGYTPTDDPEQADLILFNTCSVREKAQEKVFSDLGRVKHLKARGVLIGVGGCVASQEGAAIIERAPYVDVVFGPQTLHRLPQMLAQRARQGRPQVDISFPEIEKFDHLPPAKVDGAAAFVSIMEGCSKYCSYCVVPYTRGEEFSRPFDEVLTEVAGLADQGVKEVTLLGQNVNAYRGRMGDTSDIADFATLLEYVHEIPGIERIRYTTSHPNEFTPALIEAYARLPKLVNHLHLPVQHGSDRILSGMKRGYTVLEYKSTIRKLRAIRPDISLSTDFIVGFPGETDDDHARTMKLIDDIGFDASFSFIFSPRPGTPAAALHDDTSYEVKLARLQQLQATIEDNVRRISERRVGTVQRVLVEGPSRRDPNELMGRTECNRIVNFDGGPNAARLVGRMIDIRITLAYPHSLRGEPVLRD
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_PSYIN
Sequence: MAITVTAKQVKELRDRTAAGMMDCKKALVEAEGDLELAIENMRKSGAVKAAKKAGRVAAEGVILAKVEGSVALLAEVNCETDFVAMDKSFLAFANKIAEIALANKVASVEALNELAYDGDTVEVARANLVSKIGENISIRRLHIVEGENLGAYVHSGKIGVISVLKGGDADLSKDIAMHVAAAAPQYVKAEDVPADVVAKEKEIQLAIAVESGKPEAIAEKMVAGRMAKFSGEVSLTSQPFIKDPSIKVAKLLKDAGAEVISFIRLEVGEGIDKKVEDFAAEVAATMAASAK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_ECO45
Sequence: MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDGYRAIQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEFTVGQSISVELFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGQMGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSDLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: LMF2_BOVIN
Sequence: MAGSRVPRQLFLQGVAAVFMFAFASLYTQIPGLYGPEGILPARRTLRPQGKGRWQQLWETPTLLWEAPLLGLDTAQGLELLSLLGTVLALGALLTRQLHHPLVYLLLWAAYLSVCQVGQVFLYFQWDSLLLETGFLAMLVAPLGLPPNHKQAPQGRPGGVSPHEGLPFWLVRWLLFRLMFASGVVKLTSRCPAWWGLTALTYHYETQCLPTPAAWFAHHLPVWLHKLSVVATFLIEIAVPPLFFAPVRRLRLAAFYSQVLLQVLIILTGNYNFFNLLTLVLTTALLDDTHLAAKSSTSRRKRMPSSWPKALLAMLTLLLELAVYGLLACGVVHYFGLEVDWEQHVVRSRTMFTFHQLSQWLKTVTLPTMWLGAASLAWELLTALWRWVQVRGSLRKLCAAVQLSVFGTATVALFLISLVPYSYMEPSSHGRLWTGAHRLFSTVEHLQLANSYGLFRRMTGLGGRPEVVLEGSYDGHQWTEIEFMYKPGNLSRPPPIVVPHQPRLDWQMWFAALGPHTHSPWFTSLVLRLLQGKEPVIRLVQNHVPSYPFHQQPPTYVRAQLYKYWFSHPWEQGQWWRRQWVEEFFPSVSLGDPALDMLLRQFGLQDKSPPRAGGSSNTLSQALHWVRKQLSPLEAPALLWGLLGAVGAIKVMQALLGPQSLPRTKEEKHKPAPQEDSVAASKQASPAPNISSGSQTPRRKKSP
What is the function of this protein?
Involved in the maturation of specific proteins in the endoplasmic reticulum.  May be required for maturation and transport of active lipoprotein lipase (LPL) through the secretory pathway (By similarity).
What are the official names of this protein?
Lipase maturation factor 2.
What is the protein family that this protein belongs to?
Belongs to the lipase maturation factor family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL15_HYDVU
Sequence: MGAYKYMQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQIKFARSLQSVAEERAGRHCGGLRVLSSYWVGEDSTYKFFEVVLVDTFHKAIRRNPDTQWITKAVHKHREMRGLTSAGKKSRGLGKGHKFHLTIGGSRRAAWKRRNTLQLHRYR
What are the official names of this protein?
60S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
Protein: Y189_MYCGE
Sequence: MFKNNLRFTSWINQHKFYQLDLSLKTRSIKQIVLTLVFKTLVLGFFGLIVIFPFYLMVVVSFASDERALDTRTPILWPDSWNFDNFSRVLSDGKYLNAIVVNTLVTVLSVLLTLFFTICMGYSFSLRKWKYKKLVWFFFLSVLILPESALLIGQYRIVIVANWNNPNSPLIVLGLIMPFVSSVFSGFMYRTSFEAIPSQLKESALIDGCNGFNYFLKIALPMVKSTSWTVGILTAFSAWNSYLWPLLLLGNRVDLNINLWVLQQGILDANSSDEQIRTLLNLKMSAAILAILPMFIIYFLFHKRIMNAIKNRANTIKG
What is the function of this protein?
Probably part of a binding-protein-dependent transport system.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Probable ABC transporter permease protein MG189.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSMA_MARSD
Sequence: MQTRHRAKKSLGQNFLQDANIARKIVDSLKITENDSIIEIGPGQGALTKFILEAGPESLTLVEKDRDLAPALEAEYPEARVELEDALKFDWAGLDPDRNWKIVGNLPYNVASKIMWDIAAQCNATCVFMVQHEVAQRVTSGPGSKKYGAISVWIQSFCRTDYLFKVPPTVFKPKPKVDSAVIKFFPLPEEEKPSDIEGLAKLVKYCFQYRRKQLGKILKSFISDAVIQWAEKEGVSLTDRPEALSPLQFQSLYKSVKNDFPS
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2H_XENLA
Sequence: TPAQFDEMIKVTTIIYGLANFSDYGCHCGLNNQGMPVDDIDWCCHSQDCCYNKAEMSGCNPVTQTYRFYVEEQKKVECMKASNRCEKMICECDEKAANCFRKELEDYNIYFRNFSSLGACRGPRPFC
What is the function of this protein?
Major protein of the aragonitic otoconia.  It is unlikely that this protein has phospholipase A2 activity.
What are the official names of this protein?
Phospholipase A2 homolog otoconin-22, Oc22.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATP6_ALBFT
Sequence: MRLSPDEIIFWQHGFLKLNATIVFTWGLMLVLAVGSKLITRKLSTGLKRSRWQNLLEIVVTAIEKQIEEVGLRDPKKYLGFLGTLFLFVATASLCTVIPGYEPPTGSLSTTAALAFCVFVAVPFFGIKDQGLGGYLKSYVEPTVIMLPFNIISEISRTLALAVRLFGNMMSGAMIIGILLTITPFIFPIVMTALGLLTGMVQAYIFSILAAVYIAAATRGRKPKPEPGEKH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RIMM_POLSJ
Sequence: MGANSSSPAGLTPSSLPDDAIEVGRILDAWGVKGWVKILPHSTDPEALFSAKSWFLQAPEAKFRPGFNAFSGTVLLSVDEAKTHSDTVVAKFSGQDDRNAAEALRGARIFLPRSSFPVASKDEYYWVDLIGLNVVNREGVPLGQVRDLMTTGPHSVLCVEYTAQQEDGTAVTAERMIPFVSAYIDTVDIAGKCITVDWQPDY
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ2_COREF
Sequence: MNNAEWANKDYYADLGVSKNASAEDIKKAYRKLARENHPDKNPGDKVAEDRFKKAAEAYDVVGDETKRREYDDLKKLLASGGIRGGFGSGGADFPGGFRSTQGFDASDLFGGAGPGGGFSADGGLGDIFGGIFNRGSSPRQSARPTRGADVETDITLEFREAAKGTTIPVELTGEAPCNTCHGSGSASGQPSKCGQCNGSGFTSENKGAFGFSAPCTNCGGTGEVITDPCVDCRGRGTVRRTRSITVRIPAGVEDGQKVRLAGQGEAGPNGKPAGDLFVRVHVKEDPVFEREGNNIHVTVPVSFSELALGGAISVPTLDKPVKLKLAPGTPDGRTLRVRGRGVETRTAKGDLMVTVQVTVPPTLSDEAAEALRTYAEAEKKSGFDPRANWAGNNR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ 2.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCFJ_ECOLI
Sequence: MNKSMLAGIGIGVAAALGVAAVASLNVFERGPQYAQVVSATPIKETVKTPRQECRNVTVTHRRPVQDENRITGSVLGAVAGGVIGHQFGGGRGKDVATVVGALGGGYAGNQIQGSLQESDTYTTTQQRCKTVYDKSEKMLGYDVTYKIGDQQGKIRMDRDPGTQIPLDSNGQLILNNKV
What are the official names of this protein?
Uncharacterized protein YcfJ.
What is the protein family that this protein belongs to?
To Rickettsia 17 kDa surface antigen.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: U512E_DICDI
Sequence: MAIFKSISSISNSTSAMGSSNSTSNRNGFTSNDNSIAYFDGGCGGSGLGGWGGLSGWGGDGGFNGGCSGGSNTNIINLDIDIGRRRHRRCC
What are the official names of this protein?
UPF0512 protein E.
What is the protein family that this protein belongs to?
Belongs to the UPF0512 family.
Protein: SEPS_METM6
Sequence: MFKREEIIEMANKDFEKAWIETKDLIKAKKVNESYPRIKPVFGKTHPVNDTIENLRQAYLRMGFEEYINPVIVDERDIYKQFGPEAMAVLDRCFYLAGLPRPDVGLSDEKISQIEKLGIKVSEHKESLQKILHGYKKGTLDGDDLVLEISNALEISSEMGLKILEEVFPEFKDLTAVSSKLTLRSHMTSGWFLTVSDLMNKKPLPFKLFSIDRCFRREQKEDKSHLMTYHSASCAIAGESVDINDGKAIAEGLLSQFGFTNFKFIPDEKKSKYYTPETQTEVYAYHPKLKEWLEVATFGVYSPVALSKYGIDVPVMNLGLGVERLAMISGNFADVREMVYPQFYEHRLDDRDVASMVKLDKVPVMDEIYDLTKELIDLCVKNKDLKSPCELKLEKTFAFGKTKKNVKISIFEKEEGKNLLGPSILNEIYMYDGNVIGIPESFDGVKEEFKDFLEKGKTEGVSTGIRYIDALCFKITSKLEESFVSNTSEFKVKVPIVRSLSDINLKIDDIALKQIMSKNKVIDVRGPVFLNVEVKIE
What is the function of this protein?
Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys).
What are the official names of this protein?
O-phosphoserine--tRNA(Cys) ligase, O-phosphoserine--tRNA ligase, Non-canonical O-phosphoseryl-tRNA(Cys) synthetase, O-phosphoseryl-tRNA(Cys) synthetase, SepRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. O-phosphoseryl-tRNA(Cys) synthetase subfamily.
Protein: ODPB_CYAM1
Sequence: MLHKLFMYEALREAIDEEMARDKRVFVLGEDVGHYGGSYKVTKQLHTKYGDLRVLDTPIAENSFTGMAIGAAMTGLKPVVEGMNLSFLLLAFNQISNNAGMLHYTSGGNWSIPLVIRGPGGIGKQLSAEHSQRIEAYFQAVPGLKIVACSTPYNAKGLLKAAIRDNNPVLFLEHVLLYNLKQEIPKQEYVLPLDKAQVVREGSDVTIITYSRMLHHVMQAVKQLVAQGMNPEVIDLISLKPIDLETLVTSVSKTHKAIIVEECMQTGGIAAEVMAQIYSHAFDELDAPIRRLSSKDVPTPYNGYLEQACLVQPTQIVEAVKTLMST
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit beta.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PNCB_CITK8
Sequence: MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVHVAAEFRCRGDDLLGIYADAIREQVNAMQHLQLQEDEFQWLSGLPFFKADYLNWLRDFRYNPEQVCVTNDNGKLNIRLTGPWREVIMWEVPLLAVISELVHRYRSPEMGVAQALDALESKLVDFSALTADLNMSRFHLMDFGTRRRFSREVQQAIVKRLQQEPWFVGTSNYDLARRLSLTPMGTQAHEWFQAHQQISPDLATSQRAALAAWLNEYPNQLGIALTDCITMDAFLRDFGTEFATRYQGLRHDSGDPVEWGEKAIAHYQKLGIDPLSKTLVFSDNLDLKKAVDLYRHFSSRVQLSFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPHIKKAS
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: BZP61_ARATH
Sequence: MAQLPPKIPTMTTPNWPDFSSQKLPSIAATAAAAATAGPQQQNPSWMDEFLDFSATRRGTHRRSISDSIAFLEPPSSGVGNHHFDRFDDEQFMSMFNDDVHNNNHNHHHHHSINGNVGPTRSSSNTSTPSDHNSLSDDDNNKEAPPSDHDHHMDNNVANQNNAAGNNYNESDEVQSQCKTEPQDGPSANQNSGGSSGNRIHDPKRVKRILANRQSAQRSRVRKLQYISELERSVTSLQTEVSVLSPRVAFLDHQRLLLNVDNSAIKQRIAALAQDKIFKDAHQEALKREIERLRQVYHQQSLKKMENNVSDQSPADIKPSVEKEQLLNV
What is the function of this protein?
Transcriptional activator.
What are the official names of this protein?
Basic leucine zipper 61, AtbZIP61, bZIP protein 61.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPD_ROSS1
Sequence: MSASEAQVIARALFDSLTGTALQALRAAASVNGELTPERVLAALPEDAPREIRNLVMALGREGNLDRLPAVVTAFEQMTRRGGARPLTGEVISAVELNPQQRERITAQLTARYGPDLELRFSVDESLIGGLIIRIGDQVLDTSLRTRMAAIQRNMMTS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: KHSE_JANMA
Sequence: MAVFTPVTLDDLSQWITQFDLGKALAIKGIPSGIENTNFFITTEFGEYVLTIFENLSFEQLPFYLNLMRHLAERGVLVPAPIATHQGNLINALHGKPAAIVSKLEGSSQMEPQAVHCAAVGAMLARMHIAAENFPIRQPNLRGLAWRNETAPIVMPYLSDSNKQLLAEEMAFQNAFAESDTYHQLQNGPIHADLFRNNVMFSGDHLTGFFDFYFAGCDTWLFDVAVTVNDWCIDVETGVLDQERVRAMLDAYHHVRPFTAAEQAAWQTMLRAGALRFWLSRLYDFHLPRDAEMLTPHDPGHFERILRLRIEQATPPLFTSAG
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: Y613_MYCPN
Sequence: MVFSFQDDTALTVALNSIKLVKNPEELIPGLIPTNPKTGIFYIAAEITNSNNFFKWGTDSNREIIKGQMYFLKKETKIPTIRTYLFQMRTHKIALNANDVWFQANNDKVKVIVDGIELDQFDPKLPNVAFFNDYQVDLVSTLTLADKQLLIRRLNLALVGMNLMVDEQATNIETFPKQIRLTTKSIDQSFDFDVEFNPKASELNVIVKVDEQPLFKLDYELVIKNSNTLQLVNRNKHLGMYIWSVADQRYQAKLLDTLQLFLQSKQMYLKEKIPLKLQDNTATFKIAKQAQPNNGENKNTNFIGYLVIAASSLFLVVVAFSFYFYKRKKNLKSHKQKAVVKTDK
What are the official names of this protein?
Uncharacterized protein MG415 homolog.
What is the protein family that this protein belongs to?
Belongs to the MG414/MG415 family.
Protein: TATB_MAIZE
Sequence: MTPTANLLLPAPPFVPISDVRRLQLPPRVRHQPRPCWKGVEWGSIQTRMVSSFVAVGSRTRRRNVICASLFGVGAPEALVIGVVALLVFGPKGLAEVARNLGKTLRAFQPTIRELQDVSREFRSTLEREIGIDEVSQSTNYRPTTMNNNQQPAADPNVKPEPAPYTSEELMKVTEEQIAASAAAAWNPQQPATSQQQEEAPTTPRSEDAPTSGGSDGPAAPARAVSDSDPNQVNKSQKAEGER
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across the thylakoid membrane.  Involved in delta pH-dependent protein transport required for chloroplast development, especially thylakoid membrane formation.  TATC and TATB mediate precursor recognition, whereas TATA facilitates translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TATB, chloroplastic, Protein HIGH CHLOROPHYLL FLUORESCENCE 106, Protein TWIN-ARGININE TRANSLOCATION B.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein. Note=The C-terminus is located in the stroma.
Protein: THIG_OLEA2
Sequence: MEHTTTHNNDPLVLGGRALESRLFIGTGKYGSDSLIPRVAEASGAQVITVALRRVDMQAAAGNVMQHIPQHMQLLPNTSGARTAEEAVRIARLARAAGCGDWIKIEVISDSRYLLPDGYETAKATEILARDGFVVLPYMNPDLYVARDLVSAGAAAVMPLGAPIGTNRGLRTQEMIGILIEEIELPVIVDAGIGRPSQACEAMEMGAAACLVNTAIASAGDPVLMASAFGAAVRAGRRAWLAGTGAVLEGQAQASSPLLGFLDS
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_BURM9
Sequence: MARIAGVNIPNHQHTEIGLTAIFGIGRTRARSICVASGVAFSKKVKDLTDADLEKLREEVGKFVVEGDLRREVTMNIKRLMDLGCYRGVRHRKGLPLRGQRTRTNARTRKGPRRAAQALKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: SYS_CHLTB
Sequence: MLDIRLIRKEPKECESRLQKKDPAISLERLLDLDKTVRQLKADSEALLAKRKVLSGQIHKAKVANENADALIQEVNTIADQLVAFETTLQEQEALLEDLMARLPNYPDEDVPVSPDKTGNQMIKSHGEVPTFPFPPKHHMQLNEALQILDFKLPAKTTGSGWPAYCNEGVLLEWALLTYLLNKQQAHGFQLWLPPLLVKRDILFGSGQIPKFDGQYYRVEDGDRSLFLIPTAEVVLNGFHSQEILNEQDLPLCYAAFTPCFRREAGAGGAHERGLVRVHQFHKVEMFAFTTPEQEEVVYQKMLHVVEEILSELQLPYQLSLLSTGDMSFTAKKTIDAEVWLPGQKAFYEVSSISKCGDFQARRSETRYRDAQGKLHFVNTLNGSGLATPRLLVAILENYQQADGSVVIPSVLRPYMNNQEILLPKTVR
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_YERPY
Sequence: MKQGIHPKYEQVTASCSCGNVIKINSTVGHDLNLDVCGECHPFYTGKQRDVASGGRVDRFNKRFSVPGAKK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RL19_ALISL
Sequence: MSNIIKAIEDAQLKQDLPKFSPGDTVIVQVKVKEGERERLQAFEGVVIAIRNRGLHSAFTVRKISNGEGVERTFQTHSPIVNSIEVKRRGAVRRAKLYYLRERSGKSARIKEKLAKK
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: TPR_PORGI
Sequence: MEKKLVPQSISKERLQKLEAQATLTPQQEEAKARKIEREKARLKELNIPTESKESKDCSPAGMINPYALTEVILERPLDWSNPRTTDIVERVLGSSMQDLSKGDSVLRAGRDQNAEVKIVDSVLTKTQRGQDGLERILESFNDYDMPPEEKEEAAPKAKKAAQKLDIDDLREQALSSTTITKEISKIILPTKNLRDDNNTVHQYREVGFQSNGAHNLWDTVVQGIAGDCYMLAALSAIAWVWPALLNMDVDIMSNQDEWRLYRYFIGRSKQTYARPSGSGTSTNEILQEGYYKVPIFARSRYWFNGEYWPALFEQAYANWKFPNDSKYNAILQIGGGWPEEALCELSGDSWFTSSGKLMLSSFTDLSLLNFMKSMCYSWKTIKPMVIVTPCWEPLPPMMPGIAAYHAYTVLGYTVSNGAYYLIIRNPWGVTEPTGDGVLSKRDWVIHFDNMKWFNLSKDDGIFALRLDKVRENFWYIAYMY
What is the function of this protein?
Thiol protease.  Probably an important virulence factor.
What are the official names of this protein?
Thiol protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family.
Protein: Y4481_MYCA9
Sequence: MPDITDLFAQRATLRRSTSLLTAFRFEQSAPERFYGTLAQDTVHLITDLWQQAEGVALRGRTVLDVGGGPGYFASAFADAGARYIGVEPDPREMHAAPQGHRGIQDPRTTYLRASGMALPLADNSVDICLSSNVAEHVPQPWRLGEEMLRVTRPGGLAILSYTVWLGPFGGHEMGLTHYFGGARAARWYTRKHGHPPKNNYGSSLFPVSVRDGLRWARDTGTLTAAFPRYHPKWAWWITKIPALREVLVSNLVLVLRPR
What are the official names of this protein?
Uncharacterized methyltransferase MAB_4481.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: RUVB_BACSU
Sequence: MDERLVSSEADNHESVIEQSLRPQNLAQYIGQHKVKENLRVFIDAAKMRQETLDHVLLYGPPGLGKTTLASIVANEMGVELRTTSGPAIERPGDLAAILTALEPGDVLFIDEIHRLHRSIEEVLYPAMEDFCLDIVIGKGPSARSVRLDLPPFTLVGATTRVGLLTAPLRDRFGVMSRLEYYTQEELADIVTRTADVFEVEIDKPSALEIARRSRGTPRVANRLLRRVRDFAQVLGDSRITEDISQNALERLQVDRLGLDHIDHKLLMGMIEKFNGGPVGLDTISATIGEESHTIEDVYEPYLLQIGFIQRTPRGRIVTPAVYHHFQMEAPRYD
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RL17_STRPJ
Sequence: MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTVEKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAERNGGYTRILKTEPRRGDAAPMAIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.