PharMolix/UniProtQA huggingface dataset:
Protein: EZRA_STRPD
Sequence: MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDSLITSLEERKQALFALPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTVNSFADIENHIFEAENLNDTFNFIRAKHEINSVESQLNLVEEDIASIREALNILKEQEEKNSARVTHALDLYEKLQASISENEDNFGSTMPEIDKQMKNIETEFSQFVALNSSGDPVEASEVLDRAEEHTIALGQITEQIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELVTLDLDRAREENAHIQERIDSLYEVFEREIAAYKVAAKNSKMLPRYLAHVKRNNEQLKDEIARLSRKYILSETESLTVKAFEKDIKEIEDSTLAVAEQFGLQEKPFSELQVTFERSIKTLTNVESGQMDVFAAVKDIEKIESQARHNLDVYVTQLHMIKRYMEKRHLPGIPQDFLSAFFTTSSQLEALMDELSRGRINIEAVSRLSEVATVAIANLEDLTYQVVQNATLTEQLLQYSNRYRSFEAGVQSSFEHALRLFEVENDYQASFDEISYALETVEPGVTDRFVNSYEKTREHIRF
What is the function of this protein?
Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation.  Inhibits FtsZ ring formation at polar sites.  Interacts either with FtsZ or with one of its binding partners to promote depolymerization.
What are the official names of this protein?
Septation ring formation regulator EzrA.
What is the protein family that this protein belongs to?
Belongs to the EzrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Colocalized with FtsZ to the nascent septal site.
Protein: YQGF_OLEA2
Sequence: MKYLGIDYGTRRTGIAVTDGAGMMAFPRRTIVMSTRDAFFAELLSVVEEERPAGVVVGLPLLAGGEETLITRQVRNFVARLRRRSSLPVYLVAEELSSFEAGEDLREAGLSFREREAVVDQQAAVRILESFLNLPEDRRIPLEG
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1309_MYCBO
Sequence: MKLHRLALTNYRGIAHRDVEFPDHGVVVVCGANEIGKSSMVEALDLLLEYKDRSTKKEVKQVKPTNADVGSEVIAEISSGPYRFVYRKRFHKRCETELTVLAPRREQLTGDEAHERVRTMLAETVDTELWHAQRVLQAASTAAVDLSGCDALSRALDLAAGDDAALSGTESLLIERIEAEYARYFTPTGRPTGEWSAAVSRLAAAEAAVADCAAAVAEVDDGVRRHTELTEQVAELSQQLLAHQLRLEAARVAAEKIAAITDDAREAKLIATAAAATSGASTAAHAGRLGLLTEIDTRTAAVVAAEAKARQAADEQATARAEAEACDAALTEATQVLTAVRLRAESARRTLDQLADCEEADRLAARLARIDDIEGDRDRVCAELSAVTLTEELLSRIERAAAAVDRGGAQLASISAAVEFTAAVDIELGVGDQRVSLSAGQSWSVTATGPTEVKVPGVLTARIVPGATALDFQAKYAAAQQELADALAAGEVADLAAARSADLCRRELLSRRDQLTATLAGLCGDEQVDQLRSRLEQLCAGQPAELDLVSTDTATARAELDAVEAARIAAEKDCETRRQIAAGAARRLAETSTRATVLQNAAAAESAELGAAMTRLACERASVGDDELAAKAEADLRVLQTAEQRVIDLADELAATAPDAVAAELAEAADAVELLRERHDEAIRALHEVGVELSVFGTQGRKGKLDAAETEREHAASHHARVGRRARAARLLRSVMARHRDTTRLRYVEPYRAELHRLGRPVFGPSFEVEVDTDLRIRSRTLDDRTVPYECLSGGAKEQLGILARLAGAALVAKEDAVPVLIDDALGFTDPERLAKMGEVFDTIGADGQVIVLTCSPTRYGGVKGAHRIDLDAIQ
What are the official names of this protein?
Uncharacterized protein Mb1309.
Protein: MCC28_ARATH
Sequence: MKRSRSQNLITEMILLLRVSLHPFVVDGCKWCLTAYPKGYNFIGYLSLYLEVADNGSLPFGWRRHARYTLTLVNQNSKKSFQPNEVQEWFDDSIKWGCPSMFPLNEIHAKDSGFLVNGELKIVAEIDILEVIGDVDVSEGISTVKETIHVNGFQLLPSQAKSVSHIFERHPEIASEIHPKNSSLRTGYMSLLLSLIETLSQSPQELSKDDLCDVYIAIGCMKNAGFKLDWLENKLYEVAQKKEDDEAGETRLREMEEKLKDLKLKCSKMEALVEEEKAKVSAAKAHLSFDDVV
What are the official names of this protein?
MATH domain and coiled-coil domain-containing protein At3g58400, RTM3-like protein At3g58400.
Protein: LEUD_GRAFK
Sequence: MEKFITLKDTVVPLDAENVDTDQIIPARFLKATDKEGFGENLFRDWRFDKNGDPIEDFVLNQDKYSGSILLAGNNFGCGSSREHAAWAIKAYGFKAVVSSYFADIFKGNALNNGLLPVQVCPEFLTKLFVAIEKDQNEKISIDLEAQKIKIESSGESESFDIDSYKKTCLINGYDDIDFLTSKLEAIKKFEQKRRGKENVPQETI
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: YQGF_SALG2
Sequence: MSDTLLAFDFGTKSIGVAIGQRITGTARPLPAIKAQDGTPDWMLIERLLKEWQPDEIIVGLPLNMDGTEQPLTARARKFANRIHGRFGVTVTLHDERLSTVEARSGLFERGGYRALNKGKVDSASAVIILESYFEQGY
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_XANOM
Sequence: MTNLLWQKPGVAVDAKIQSFLAGDDVILDREFFLHDIAASKAHAQGLQHIGILSPQELDGLSEQLDLLAEDFRGGAFVLDEQYEDCHSAIEARLTERLGDAGRKIHTGRSRNDQILVATRLWLKDKLQRVATLSAEIAKVALDRAQAEAELPVPGYTHIQRAVVSSAGMWWAGWAEAFIDNAVRATDTLQLVDSNPLGTAAGYGVNLPLDRAHTTAELGFARLQVSPIYAQLSRGKYELAALEALGSATLDLRRIAWDVSLFTSGEFAFVALPAQYTTGSSIMPNKRNPDVIELMRATHASVAAARTEIEQLLSLPSGYHRDLQSSKGAIVHGFGRGLAALELLPALLANLEWRPDKLRAAIDSGMYATDVAVEAAVAGVPFREAYKAAAEASDTAGQGRTPEGSLAARVSPGAAADLQLDVLLARWETLR
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAGP_PANAM
Sequence: MNRYLLTTLSAPLLALFFSFSLQAAMLSQEIKSGWDTFTGNVQQTWQQPDAIDVYVPAITWHNRWTYDEEHIHRYNERPWGAGGGVSRYDEKGNWHGLYLMAFKDSFNKWEPFGGYGWEATWRPLQDQNFHYGLGYTAGVTARHNWGYYPVPAILPLASIGYGSLNFQMTYIPGTYNNGNVYFAWLRWQF
What is the function of this protein?
Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors.
What are the official names of this protein?
Lipid A acyltransferase PagP, Lipid A acylation protein.
What is the protein family that this protein belongs to?
Belongs to the lipid A palmitoyltransferase family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: ATPG_CLAMS
Sequence: MGAQLRVYTQKIKSAQTTKKITRAMELISASRIQKAQQRMAASAPYSRAVTRAVSAVATFSNVDHILTTEPEKVERAAIVIFASDRGLAGAFSSSVLKESEQLAELLRSQGKEIVYYLVGRKAVGYFKFRKRDSERIWTGSTEKPEFETAKSIGDALVEKFVTPASEGGVDEIHIVFNRFVSIATQKPEVVRLLPLEVVEGVEAPVEGAVLPLYEFEPEVGDVLDALLPVYIESRIFNAMLQSAASEHAARQKAMKSASDNADKLVTTYTRLRNNARQTEITQQISEIVGGADALASSK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LEUD_NEIMA
Sequence: MKAFTKITAIVAPLDRSNVDTDAIIPKQFLKSIKRSGFGPNAFDEWRYLDHGEPGMDNSKRPLNPDFSLNQPRYQGAQILLTRKNFGCGSSREHAPWALDDYGFRAVIAPSFADIFFNNCYKNGLLPIVLTEEQVDRLFKEVEANEGYRLSIDLAEQTLTTPSGETFTFDITEHRKHCLLNGLDEIGLTLQHADEIHAFEEKRRQSQPWLFNG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: CLZ11_COCLU
Sequence: MAGDLWLVGDCTNHGGLSDAIIVSPDYRLLPEATGADIFDDVEAFWNWLHTSLPSLAQSYSWQAQPDLTRILCVGQSGGGSMAVHSALLHPEYSIKVIVSLYAPLYHNVPNLTVPRPRRILGTMPPPPRKAEGLIRSYIKQSKGSVRTGGNPFDMWELLLCLLQQGRLISLMNIKPDSRLDTPFLLRQVGKLPPLWLIHGEDDSVVGPSTICVHRVIF
What is the function of this protein?
Probable carboxylesterase; part of the gene cluster that mediates the biosynthesis of squalestatin S1 (SQS1, also known as zaragozic acid A), a heavily oxidized fungal polyketide that offers potent cholesterol lowering activity by targeting squalene synthase (SS) (PubMed:28605916).  SQS1 is composed of a 2,8-dioxobicyclic[3. 2. 1]octane-3,4,5-tricarboxyclic acid core that is connected to two lipophilic polyketide arms (PubMed:28605916).  These initial steps feature the priming of an unusual benzoic acid starter unit onto the highly reducing polyketide synthase clz14, followed by oxaloacetate extension and product release to generate a tricarboxylic acid containing product (PubMed:28605916).  The phenylalanine ammonia lyase (PAL) clz10 and the acyl-CoA ligase clz12 are involved in transforming phenylalanine into benzoyl-CoA (PubMed:28605916).  The citrate synthase-like protein clz17 is involved in connecting the C-alpha-carbons of the hexaketide chain and oxaloacetate to afford the tricarboxylic acid unit (PubMed:28605916).  The potential hydrolytic enzymes, clz11 and clz13, are in close proximity to pks2 and may participate in product release (PubMed:28605916).  On the other side, the tetraketide arm is synthesized by a the squalestatin tetraketide synthase clz2 and enzymatically esterified to the core in the last biosynthetic step, by the acetyltransferase clz6 (By similarity).  The biosynthesis of the tetraketide must involve 3 rounds of chain extension (By similarity).  After the first and second rounds methyl-transfer occurs, and in all rounds of extension the ketoreductase and dehydratase are active (By similarity).  The enoyl reductase and C-MeT of clz2 are not active in the final round of extension (By similarity).  The acetyltransferase clz6 appears to have a broad substrate selectivity for its acyl CoA substrate, allowing the in vitro synthesis of novel squalestatins (By similarity).  The biosynthesis of SQS1 requires several oxidative steps likely performed by oxidoreductases clz3, clz15 and clz16 (Probable).  Finally, in support of the identification of the cluster as being responsible for SQS1 production, the cluster contains a gene encoding a putative squalene synthase (SS) clz20, suggesting a likely mechanism for self-resistance (Probable).
What are the official names of this protein?
Probable carboxylesterase clz11, Squalestatin S1 biosynthesis cluster protein clz11, Zaragozic acid A biosynthesis cluster protein 11.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
Protein: ENO_PSEAB
Sequence: MAKIVDIKGREVLDSRGNPTVEADVILDNGIVGSACAPSGASTGSREALELRDGDKSRYLGKGVLKAVANINGPIRDLLLGKDAADQKALDHAMIELDGTENKAKLGANAILAVSLAAAKAAAQAKGVPLYAHIADLNGTPGQYSMPVPMMNIINGGEHADNNVDIQEFMVQPVGAKNFAEALRMGAEIFHHLKAVLKARGLNTAVGDEGGFAPNLSSNEDALAAIAEAVEKAGYKLGDDVTLALDCASSEFFKDGKYDLEGEGKVFDAAGFADYLAGLTQRYPIISIEDGMDESDWAGWKGLTDKIGAKVQLVGDDLFVTNTKILKEGIEKGIGNSILIKFNQIGSLTETLEAIQMAKAAGYTAVISHRSGETEDSTIADLAVGTAAGQIKTGSLCRSDRVSKYNQLLRIEEQLGAKAPYRGRAEFRG
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: HXC8_HUMAN
Sequence: MSSYFVNPLFSKYKAGESLEPAYYDCRFPQSVGRSHALVYGPGGSAPGFQHASHHVQDFFHHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSANTNSSEGQGHLNQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGARDEEKVEEEGNEEEEKEEEEKEENKD
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-C8, Homeobox protein Hox-3A.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASTD_ALIFM
Sequence: MTHWIAGDWVSGEGEMIQSLSPYNSEVVWKGESATEAQVESAVNAARNAFIEWKKLPFENRQAIVERFAELVKDNADSIAEVIAKETGKPFWETKTEAGAMVGKIAISIRAYHERTPYKEREAAGNKIVLRHRPLGVMAVFGPYNFPGHLPNGHIVPALLAGNTVVLKPSEQTPWTSEVIMKLWQKAGLPKGVINLVQGARSTGEALANAKGIDGLLFTGSANTGHILHRQFAGDTGKMLALEMGGNNPMVISKAFGDLDATVYTIVQSAFISAGQRCTCARRLYVPEGEKGDALLARLVDVTKNIHVDQPFSETTPFMGSQISIAAAEFILNAQKKLQALGGELLLEARSLGHAFVSPGIIDATNVAELPDEEYFGPLLQVIRYTTLAQAVELANDTRYGLSAGLVSTDDSEWDYFVEHIRAGIVNRNRQLTGASGDAPFGGPGASGNLKPSAYYAADYCAYPMASMEGDACEIPEQLSPGLTL
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: RS19_PELPD
Sequence: MARSIKKGPFIDEHLAKKVLAEGPNSKKIIKTWSRRSTITPDFIGLSFAVHNGRKFVPVYVTENMVGHKLGEFSPTRTFHGHAADRKSKAKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: FPG_SHIF8
Sequence: MPELPEVETSRRGIEPHLVGATILHAVVRNGRLRWPVSEEIYRLSDQPVLSVQRRAKYLLLELPEGWIIIHLGMSGSLRILPEELPPEKHDHVDLVMSNGKVLRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDDFNGEYLHQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVLLRSIEQGGTTLKDFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRQCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: SYGB_RICCK
Sequence: MSELLLELFSEEIPAFMQKNAEKGYLNVFTKIFEENKIFAKVKVFVGPRRITLHATHLPKVTLPKDTAIKGPSLNASEAAINGFCKAHNVSKLELFTKLINNQLYYFFIKKTEEREIKEILPEIIIEAINKYSWTKSMFWGDYNIKWVRPLRNILCIFDGEILPMQFGHLTANNITYGHRLTDNKKIEVENFEDYKNKLSENHVILERTKREEIIKAGLLELANSHDLTIKEDNRLIEEVSGLTEFPVVLLGRIPLKFLELPKEVLISSMRRHQKYFCLFDKAGNFAPYFLFVSNGRFVNAELVIKGNEKVLAARLADALYFYKQDIAKTLESNLSKLLAVTFHVKLGNLREKVDRITNICNYIAPNNKDLIMAAKLCKSDLVSEMVGEFPDLQGIMGYYYAKHDGLDEEVATAIKDHYKPQGLSDNVPNGNAALLATADKIDSLVGLMIAGEAPTGSGDPYALRRQALGIIRIIIENKLELNLNDLINFSINLYKDSSDKNKDLIISFLKERIKFYFKNNYDISLINAVLDLSAEDLVSVSLKLNTLQKFLAEDAGKQLLNAYKRASNIIGDQKITGLVDGNLFTTQSEKELFAVMQKILPQIIDSITDKDYERVLNLLSSLLAPITSFFGNVLVNDPDPKIVQNRLSLLQNTCELFHKIAKFNRL
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOD_MYCBP
Sequence: MTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVTQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGVTLRDVAVDVAAVALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAASNRSALARIATVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS3_MYCLE
Sequence: MTLDPDIAVRLKRNAEGLFTAVVQERSSGDVLMVAWMDDQALARTLETREANYYSRSRAEQWIKGSTSGNTQHVHSVRLDCDGDTVLLTVDQVGGACHTGAHSCFDSAMLLAPQD
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_CLAM3
Sequence: MLIAQRPTLTEESISEFRSRFVIEPLEPGFGYTLGNSLRRTLLSSIPGAAVTSIRIDGVLHEFSTVPGVKEDVTEIILNIKGLVVSSEHDEPITAYLRKQGAGQVTAADISAPAGVEIHNPELVIATLNEKAKFELELTIERGRGYVSATQNRSEFSEAGQIPVDSIYSPVLKVTYRVEATRAGERTDFDRLVVDVETKSAITPRDAIASAGRTLTELFGLARELNSAAEGIEIGPAPVDAVLSSELSMPIEDLDLSVRSYNCLKREGINNVSELVALSETQLMNIRNFGQKSVDEVKDKLVELGLSLKDAVPGFDGAHYYSYDEDETTTN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: DAAF1_BOVIN
Sequence: MHPEASEPVVDGVAEQECAQEPGVEESAGDHGNAGEGGRKEEMNDPKETCVGPLNTSCLSEQKQSGDSWSDGRLAHQRADKEDRGARMTKKFLQKLCKQHKLYITPALNDTLYLHYKGFDRIENLEEYTGLRCLWLECNGIQKIENLEAQTELRCLFLQVNLLHKIENLEPLQKLDALNISNNYIKTIENLSCLPVLNTLQMAHNHLETVEDIQHLRECARLCVLDLSHNKLSDPEILRVLESMPDLRVLNLMGNPVIKNIPNYRRILTVRLKHLTYLDDRPVFPKDRACAEAWARGGYAAEKEERQQREMRERKKITDSIEALAALRRQAEERKWQRASQEQGEEPTPAGAGDVDAEVEGEEEPQEKDTRQKIEQFVKESFEAKDELFPEKPEEPSLLEELPLDVGEPKGVLPSEVLPASPRAAWAELAPQTVATESASGTEPDGAENLEATRLETKEQLFIDDLPNLEDVNAGESLGDRDREQCFPKITAISSLSDASEPDMDDISLLALENTSSDTLSSIFAVPKDTSWRVETETPFTDILKVAPERDPETQRKASEVPRPLIQELGDDEEPSGPPPLPPVCEGEAVPAPCTEDSDGDLLPAPAPGNGPEKDEVQSEVEPEERLGSEAGENREDIEFGLD
What is the function of this protein?
Cilium-specific protein required for the stability of the ciliary architecture.  Plays a role in cytoplasmic preassembly of dynein arms (By similarity).  Involved in regulation of microtubule-based cilia and actin-based brush border microvilli (By similarity).
What are the official names of this protein?
Dynein axonemal assembly factor 1, Leucine-rich repeat-containing protein 50.
What is the protein family that this protein belongs to?
Belongs to the DNAAF1 family.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: DRE2_UNCRE
Sequence: MERMLFLSPPSLAAHPEKLSTILSAHAQYSTELQMLDRLAAGLVSLPESTYDIVMFLIDADCLKTGSTPRMSRGVIESIVRALRPGGKLKSEHGLFASPDYPDRTELVLAGLVFDDNGDLVKPNFGAQDTVPLKLGKKKKATPAASSGDGAEANGVTVNMPIATDSKRNGQGAAVQGLGFVDFSDDLDLPPEDDDELIDEEALMDEEDMGRPIVQPPECRPKAGKRRRACKDCTCGLAERLHEEDTAKRANADAALETLKLGSNDLAEVDFTVQGKMGSCGNCALGDAFRCDGCPYIGLPPFKPGEEVRLLSNDVQL
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35.  Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18.  TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
What are the official names of this protein?
Fe-S cluster assembly protein DRE2, Anamorsin homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: U2A2A_ARATH
Sequence: MSEFEDHEGNGTVADAIYDEENGGRDGEIEDQLDSKPKRESRDHERETSRSKDREREKGRDKDRERDSEVSRRSRDRDGEKSKERSRDKDRDHRERHHRSSRHRDHSRERGERRERGGRDDDDYRRSRDRDHDRRRDDRGGRRSRRSRSRSKDRSERRTRSRSPSKSKQRVSGFDMAPPASAMLAAGAAVTGQVPPAPPTLPGAGMFPNMFPLPTGQSFGGLSMMPIQAMTQQATRHARRVYVGGLSPTANEQSVATFFSQVMAAVGGNTAGPGDAVVNVYINHEKKFAFVEMRSVEEASNAMSLDGIIFEGAPVKVRRPSDYNPSLAATLGPSQPSPHLNLAAVGLTPGASGGLEGPDRIFVGGLPYYFTESQVRELLESFGGLKGFDLVKDRETGNSKGYAFCVYQDLSVTDIACAALNGIKMGDKTLTVRRANQGTMLQKPEQENVLLHAQQQIAFQRVMLQPGAVATTVVCLTQVVTEDELRDDEEYGDIMEDMRQEGGKFGALTNVVIPRPSPNGEPVAGLGKVFLKYADTDGSTRARFGMNGRKFGGNEVVAVYYPEDKFEQGDYGA
What is the function of this protein?
Necessary for the splicing of pre-mRNA.
What are the official names of this protein?
Splicing factor U2af large subunit A, U2 auxiliary factor 65 kDa subunit A, U2 small nuclear ribonucleoprotein auxiliary factor large subunit A, U2 snRNP auxiliary factor large subunit A.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DTD_ALKMQ
Sequence: MRAVVQRIKEGKVTVEGEITGECNFGLLVYLGVGREDTVEDAKYLAEKIVNLRIFEDQEEKLNLSVKDVGGSLLVISQFTLFGDCRKGRRPSFSEAAKPDEADYLYQEFVRCCNDVGMTVGTGVFQAHMMVHAINDGPVTMLIDSKKTF
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS2_THEMA
Sequence: MMTLYPVVVQERTTGEVLMLAYANEEALELTKKTGYAHFFSRERQKIWKKGETSGNTMRVVEIRRDCDDDAYLYIVDFPEDKVACHTGNRSCFFKVEHRFEETGSPTFWLELYRLVRKRKEEMPEGSYTVKLFKEGKGKIAKKFGEEAVEVITGYLQNDRENLVWEIADMMYHLTVLMADAGVTVQDVMRELEKRRK
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisIE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAX2_ARATH
Sequence: MASTTLSDLPDVILSTISSLVSDSRARNSLSLVSHKFLALERSTRSHLTIRGNARDLSLVPDCFRSISHLDLSFLSPWGHTLLASLPIDHQNLLALRLKFCFPFVESLNVYTRSPSSLELLLPQWPRIRHIKLLRWHQRASQIPTGGDFVPIFEHCGGFLESLDLSNFYHWTEDLPPVLLRYADVAARLTRLDLLTASFTEGYKSSEIVSITKSCPNLKTFRVACTFDPRYFEFVGDETLSAVATSSPKLTLLHMVDTASLANPRAIPGTEAGDSAVTAGTLIEVFSGLPNLEELVLDVGKDVKHSGVALEALNSKCKKLRVLKLGQFQGVCSATEWRRLDGVALCGGLQSLSIKNSGDLTDMGLVAIGRGCCKLTTFEIQGCENVTVDGLRTMVSLRSKTLTDVRISCCKNLDTAASLKAIEPICDRIKRLHIDCVWSGSEDEEVEGRVETSEADHEEEDDGYERSQKRCKYSFEEEHCSTSDVNGFCSEDRVWEKLEYLSLWINVGEFLTPLPMTGLDDCPNLEEIRIKIEGDCRGKRRPAEPEFGLSCLALYPKLSKMQLDCGDTIGFALTAPPMQMDLSLWERFFLTGIGSLSLSELDYWPPQDRDVNQRSLSLPGAGLLQECLTLRKLFIHGTAHEHFMNFLLRIPNLRDVQLRADYYPAPENDMSTEMRVGSCSRFEDQLNSRNIID
What is the function of this protein?
Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.  Promotes the senescence.  Is necessary for responses to strigolactones and karrikins.  Contributes to the selective repression of axillary shoots and moderates the branching by regulating negatively the auxin transport in primary stems, in an AXR1-independent manner (PubMed:11487692, PubMed:11874909, PubMed:15737939, PubMed:16546078, PubMed:22357928, PubMed:9351240).  Required for the progression of leaf senescence mediated by methyl jasmonate (PubMed:26507893).  Required at each node to suppress axillary bud growth (PubMed:17346265).
What are the official names of this protein?
F-box protein MAX2, F-box/LRR-repeat protein 7, Protein KARRIKIN INSENSITIVE 1, Protein MORE AXILLARY BRANCHING 2, Protein ORESARA 9.