PharMolix/UniProtQA huggingface dataset:
Protein: PSBI_NEOYE
Sequence: MFTLKIFVYTTVIFFISLFVFGFLSNDPSRNPNRKDLE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RS3_STRA5
Sequence: MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINKELADASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRGQLNKLTGKQVHINIIEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGADIARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: NUSB_CHRVO
Sequence: MKTARRRAREFAVQGIYEWELNPDRPASLIEKHLRENEYFAKADEALFRSILYGVLKDVELLSAQVGRYYERAEDEVSPVERAVLLMAALELTQSPETPYPVIINEAIEITKTFGGTDGHKFVNGVLDKLAAEVRGDEVLAQKQRRKQD
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: HBB_CANLF
Sequence: VHLTAEEKSLVSGLWGKVNVDEVGGEALGRLLIVYPWTQRFFDSFGDLSTPDAVMSNAKVKAHGKKVLNSFSDGLKNLDNLKGTFAKLSELHCDKLHVDPENFKLLGNVLVCVLAHHFGKEFTPQVQAAYQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: HSLO_PSEU2
Sequence: MHDFPNIDFTQRFIFDESDVRGELVALERSYAEVLAKHPYPEPVAQLLGELMAAAALLVGTLKFDGLLILQARSSGAVPLLMVECSSERELRGIARYDEALVTAGAGLQDLMPDGSLALTIDPNKGKRYQGIVALDGVDLSESLSNYFVMSEQLGTRFWLKADGHRARGLLLQQLPIAQITDPEERDASWEHVITLANTLTAEEMLGLDNQTILHRLYHEDPVRLFDEQPICFRCSCSRERSANALASLGLEDAQQLVIEHNGTIEIDCQFCNQRYLFDATDVAQLFAGGGVDSPSDTRH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPS1_PHYPO
Sequence: MNHPLRIHEIRLPWKHTPMNPHYAFVREQIVALLNELGLCEEEKEKDRRDGVITMGAYIYPDAGPNELLFGTLFVLWLFFFDDIFDESKFLKGESSQAAERTLQMFRTRQPPVNATTGLSMGIVQLEKLLLRIFKMAKDLAHGPYVISRFMETCEFYITEGAIPMDKFRFRKELPKLDEYLAVRTIDGAGEACIVCSEIVAHLALPEHIINEPRIKRMREITGQQIVYSNDIYSYHREKIHNNSVNALNIRCLTKSFNDALTDQINQVNEWVLEFEALKNSLYESTLWENNLDVYITGMENTMMGCKIWSESCTRYDLNALLHITPDKNEFPER
What is the function of this protein?
Terpene synthase that catalyzes the cyclization of farnesyl diphosphate (FPP) into a mixture of sesquiterpenes with gamma-muurolene as the most abundant compound and (-)-beta-caryophyllene, alpha-muurolene, and 4 unidentified sesquiterpenes as minor compoundss (PubMed:31839833).  TPS1 shows also monoterpene synthase activity and can also use geranyl diphosphate (GPP) as a substrate to convert it into a mixture of cyclic and acyclic monoterpenes, including myrcene and linalool (PubMed:31839833).  P. polycephalum has a unique biology and these volatile terpenoids could function in internal communication of P. polycephalum, to mark the territory that have been explored, or they may be involved in chemotaxis (Probable).
What are the official names of this protein?
Terpene synthase 1, TPS1, Terpene cyclase TPS1.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: CINA_CLOPE
Sequence: MKAEIMAIGTEILLGDIVNTNAQFLAKELANLGIGVYHQSVVGDNSERILEAFDNAFKNCDTIITTGGLGPTKDDLSKELAAKYFNMEMCLREELLCDLEDYFKKNNLEMTENNKKQCYFPKEAIILPNPNGTAPGAILEGENNKRIILLPGPPREMEPMFTNHVVPYLSKFTDSVLVSKILRVFGIGESKMEDLVCDLLDNENPTVAPYAKNIDVILRITAKGKDKEEAEKLIAPMEKEIRKRLGDNIYGEGEVTLEEVVGKLLVDKKMTVSTAESCTGGMVASTLINYPGISEVFMEGAVTYSNEAKMKRLGVKKETLEDFGAVSEECAREMAKGIAKNAGTRIGISTTGIAGPGGGTEEKPVGLVYAGLCIDGITKVKKFNFKADRQKVRTRTMMNVLDWLRRELEKID
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: PPAT_MOUSE
Sequence: MAEPGSQGHTVGPLLLLLLLLLPRALPEGPLLFVALVFRHGDRAPLASYPTDPHKEAASTLWPRGLGQLTKEGIRQQLELGRFLRRRYKAFLSPEYKREEVYIRSTDFDRTLESAQANLAGLFPEAAPGSPETDWKPIPVHTVPVSEDKLLRFPMRSCPRYHELLRESTEAADYQEALEGWTDFLTRLGNFTGLSLVGEPLRRAWKVLDTLICQRAHGLDLPSWASPDVLRTLSQISALDIRAHVGPPRAAEKAQLTGGILLDAILSNFSRTQRLGLPLKMVMYSAHDSTLLALQGALGLYDGNTPPYAACMAFEFRGSSREPEEEDGENVTVSLIYRNDTSRPPLPLRVPGCPAPCPLGRFQQLTAPARPPAHGAPCHGSYEPASPPATVPLLAGAVAVLAVLSLGLGLLAWRPRCLRALGGTV
What is the function of this protein?
May dephosphorylate receptor tyrosine-protein kinase ERBB4 and inhibits its ligand-induced proteolytic cleavage.  May play a role in odontogenesis.
What are the official names of this protein?
Testicular acid phosphatase, Acid phosphatase 4.
What is the protein family that this protein belongs to?
Belongs to the histidine acid phosphatase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: KCAB2_HUMAN
Sequence: MYPESTTGSPARLSLRQTGSPGMIYSTRYGSPKRQLQFYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKGYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNADQLMENIGAIQVLPKLSSSIIHEIDSILGNKPYSKKDYRS
What is the function of this protein?
Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits (PubMed:7649300, PubMed:11825900).  Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability (By similarity).  Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity (By similarity).  Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore (PubMed:7649300, PubMed:11825900).  Promotes KCNA4 channel closure (PubMed:7649300, PubMed:11825900).  Modulates the functional properties of KCNA5 (By similarity).  Enhances KCNB2 channel activity (By similarity).  Binds NADPH and has NADPH-dependent aldoketoreductase activity (By similarity).  Has broad substrate specificity and can catalyze the reduction of methylglyoxal, 9,10-phenanthrenequinone, prostaglandin J2, 4-nitrobenzaldehyde, 4-nitroacetophenone and 4-oxo-trans-2-nonenal (in vitro) (By similarity).
What are the official names of this protein?
Voltage-gated potassium channel subunit beta-2, K(+) channel subunit beta-2, Kv-beta-2, hKvbeta2.
What is the protein family that this protein belongs to?
Belongs to the shaker potassium channel beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, axon. Synapse, synaptosome. Cytoplasm, cytoskeleton. Note=Recruited to the cytoplasmic side of the cell membrane via its interaction with pore-forming potassium channel alpha subunits. Associates with microtubules when unphosphorylated.
Protein: MALT_VIBC1
Sequence: MWIPSKLTRPGRLHNAIVRPRVLDLLQQAPYYKLVLFRSPAGYGKTTMAAQWLSDKPNVGWYSIDDSDNDGFRFVNYLLQALNKATNYNCSNAQKLAEKRQFSSLRSLFSEVFAEMADFQHECYVVLDDYHLITNDEIHESMRFFLKHMPDNLTVVVTSRAAPPLGTANLRVRDLMIEIGNEMLAFDTEETTRFFNQRIADGIDEDMANNLRTYVEGWPSALQLIALQAQHQNRTLAQTVESVSQFNHAHLWDYLVEEVFDLLDQETRHFLMQVSVLDHFNDELVFALTQREDALGMIESLNRFGLFIYPLEGEQNWFRFHNLFGEFLSHERLARIPQQEKDLHRNAAVAWLKQKAPHQAIHHAQKSNDTDLIVEILNEFGWKMFNQGELTTLESAINQLDKDLLFSHPKLSMLRAWLAQSQHRYNQVGKLLAEAEEEHKKRNIEIDSGYQGQANALLAQVAINSNQPEHALELAELALSQLDPTVYRSRIVATSVVGEVNHVLGKLDRALPMMQQTEKLARQYQVYHQALWAILQQSEIMIAQGYVQAAFELQDSGFRLIEEQQLQHVPLHEFLLRIRAQVLWCWNRLDEAEECAYKGLQILENHSPSKHLHSYSMLARIAIGRGELDKAGKFIEHIQHLMKQSTYHVDWTANASLSLILFWQARGNTEAIQEWLNTAVRPESACNHFQQLQWRNIARAHINLGQYDEAREALDFLQSEAHRTNLVTDTNRNLVVEAILAARQKDEEQAKTLLKEALVMTNQTGMVGNFLTDGATIGGLLEKLSLRHELGDLERHRAQQLMKDISSNQRSRSIHFDEDFIEKLVNHPNVPELVRTSPLTQREWQVLGLIYSGFSNEQIAQELDVAGTTIKTHIRNLYQKLNIANRKEAIVTAENLLQLMGY
What is the function of this protein?
Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides.  Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
What are the official names of this protein?
HTH-type transcriptional regulator MalT, ATP-dependent transcriptional activator MalT.
What is the protein family that this protein belongs to?
Belongs to the MalT family.
Protein: CC124_MOUSE
Sequence: MPKKFQGENSKSAAARARRAEAKAAADAKKQKELEDAYWKDEDKHVMRKEQRKEEKEKRRLEQLERKKETQRLLEEEDSRLKGGKAPRVAPAKVTRAQIEDSLRREQRAEPVEKAKSHLELPLEENLNRRLQEEGSVEARTVEDAIAVLSVAEEADRHPERRMRAAFTAFEEVQLPRLKQENPNMRLSQLKQLLKKEWLRSPDNPMNQRALPFNAPK
What is the function of this protein?
Required for proper progression of late cytokinetic stages.
What are the official names of this protein?
Coiled-coil domain-containing protein 124.
What is the protein family that this protein belongs to?
Belongs to the CCDC124 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=Colocalizes with gamma-tubulin at interphase, prophase, metaphase, and anaphase. Relocates from centrosome to midbody at telophase (By similarity).
Protein: SYT_LISMF
Sequence: MKITFPDGAVKEFEPGVSTADIAASISPGLKKKALAGKLNGELLDLVTPIHEDGAIEIVTPDHEDALGILRHSTAHLMAQALKRLYPDVKFGVGPAIESGFYYDIDTEAVISDESLVEIEKEMQKIVRENVPIEREVVSREEAIKRFKAIGDQYKLELIEAIPEDETVTIYTQGEFFDLCRGVHVPSTGKIQVFKLLSVAGAYWRGDSNNKMLQRIYGTAFFDKNGLKEFIQMQKEAKERDHRKLGKELDLFANSIEVGQGLPLWLPKGATIRRVIERYIVDKEERLGYNHVYTPIMANVELYKTSGHWDHYHEDMFPTMKMDNEELVLRPMNCPHHMMIYKNDIHSYRELPIRIAELGMMHRYEMSGALSGLQRVRGMTLNDAHVFVRPDQIKDEFKRVVELILEVYKDFDIKDYSFRLSYRDPKNTEKYFDDDAMWEKAQAMLKSAMDEMEMDYFEAEGEAAFYGPKLDVQVKTAIGKEETLSTVQLDFLLPERFDLTYIGEDGEKHRPVVIHRGVVSTMERFVAYLIEEYKGAFPTWLAPVQMELIPVNADAHLDYAKGVQDKLQRAGLRAEVDDRNEKLGYKIREAQTKKIPYALVLGDQEVEAGSVNVRRYGSKDSETMDLDAFIAQVVAEVSKY
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUN_PAEPO
Sequence: MKKKGLKKTFFVIASLVMGFTLYGYTPVSADAASVKGYYHTQGNKIVDESGKEAAFNGLNWFGLETPNYTLHGLWSRSMDDMLDQVKKEGYNLIRLPYSNQLFDSSSRPDSIDYHKNPDLVGLNPIQIMDKLIEKAGQRGIQIILDRHRPGSGGQSELWYTSQYPESRWISDWKMLADRYKNNPTVIGADLHNEPHGQASWGTGNASTDWRLAAQRAGNAILSVNPNWLILVEGVDHNVQGNNSQYWWGGNLTGVANYPVVLDVPNRVVYSPHDYGPGVSSQPWFNDPAFPSNLPAIWDQTWGYISKQNIAPVLVGEFGGRNVDLSCPEGKWQNALVHYIGANNLYFTYWSLNPNSGDTGGLLLDDWTTWNRPKQDMLGRIMKPVVSVAQQAEAAAE
What are the official names of this protein?
Endoglucanase, Cellulase, Endo-1,4-beta-glucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
Protein: SYFA_PSEPK
Sequence: MENLDALVSQALEAVERAEDINALEQIRVNYLGKKGELTQVMKTLGNLPAEERPKVGALINDAKERVTVVLNARKAAFEEAELSARLAAECIDVTLPGRGQATGGLHPITRTLERIEQFFTHIGYGIAEGPEVEDDYHNFEALNIPGHHPARAMHDTFYFNANMLLRTHTSPVQVRTMESTQPPIRIVCPGRVYRCDSDITHSPMFHQVEGLLIDRDINFADLKGTIEEFLRVFFEKELAVRFRPSFFPFTEPSAEVDIQCVMCSGNGCRVCKQTGWLEVMGCGMVHPNVLRMSGIDPEEFQGFAFGMGAERLAMLRYGVNDLRLFFDNDLRFLAQFR
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDIB_ECOUT
Sequence: MDVTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPFTYMAFEVDNDSFPAAIEGLKALKMRGTGVSMPNKQLACEYVDELTPAAKLVGAINTIVNDDGYLRGYNTDGTGHIRAIKESGFDIKGKTMVLLGAGGASTAIGAQGAIEGLKEIKLFNRRDEFFDKALAFAQRVNENTDCVVTVTDLADQQAFAEALASADILTNGTKVGMKPLENESLVNDISLLHPGLLVTECVYNPHMTKLLQQAQQAGCKTIDGYGMLLWQGAEQFTLWTGKDFPLEYVKQVMGFGA
What is the function of this protein?
The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate.  Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively.  It can use both NAD or NADP for catalysis, however it has higher catalytic efficiency with NAD.
What are the official names of this protein?
Quinate/shikimate dehydrogenase, NAD-dependent shikimate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: SNX32_MOUSE
Sequence: MEEQHQEAGNESKPSSTSVDLQGDSPLQVEISDAVSERDKVKFTVQTKSGLPHFAQSEFSVVRQHEEFIWLHDTYVENEEYAGLIIPPAPPRPDFEASREKLQKLGEGNSSITREEFSKMKQELEAEYLAIFKKTVAMHEVFLQRLAAHPTLRRDHNFSVFLEYSQDLSVREKNRKEVLGGLLRSIVRSADEVLITGISGLKEVDDFFEHERTFLVEYHTRIRDTCQRADRVMHSHKCLADNYIPISAALSSLGTQEVNQLKRSFLKLAELFERLRKLEGRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALADYENANKALDKARTRNREVRPAESRQQLCCQRFERLSDSAKQELMDFKSRRVSSFRKNLIELAELELKHAKASTLLLQNTLVALKGEP
What is the function of this protein?
May be involved in several stages of intracellular trafficking.
What are the official names of this protein?
Sorting nexin-32, Sorting nexin-6B.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
Protein: NUOI_PROMH
Sequence: MTLKELVTGFGTQVRSIWMIGLHAFAKRETQMYPEEPVNVAPRYRGRIVLTRDPDGEERCVACNLCAAVCPVGCISLQKAEHEDGRWYPEFFRINFSRCIFCGLCEEACPTTALQLTPDFEMGEFKRQDLVYEKDDLLISGPGKYPEYNFYRKTGMAINGKDKGEADDEAKPIDVKSLLP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FUCM_SALCH
Sequence: MLKTISPLISPTLLKVLAEMGHGDEIIFSDAHFPAHSLGPQVIRADGLSVSDLLRAIIPLFELDSYAPPLVMMAAVEGDTLDPSVEARYRDALSLEAPCPDIVRIDRYAFYERAQKAFAIVITGECAKYGNILLKKGVTP
What is the function of this protein?
Involved in the anomeric conversion of L-fucose.
What are the official names of this protein?
L-fucose mutarotase, Fucose 1-epimerase, Type-2 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. FucU mutarotase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL37A_PYRIL
Sequence: MPFSHTKIVGPAGRYGARYGMGLRRKITAIEIKQRGKHRCPSCRSLVRLKRLAFGIWQCPKCGFTFAGGAWVPQTVMGKTLTPEELKEVEIQKARWRETGK
What are the official names of this protein?
50S ribosomal protein L37Ae, Ribosomal protein L43e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL43 family.
Protein: Y4937_BACCR
Sequence: MIKPLIEFCVGNLASGSQAALEKLEKDPNLDVMEYGCLGYCGICFEGPFALVNGEVVQGATVEELVNNVYEYLDENPMF
What are the official names of this protein?
UPF0349 protein BC_4937.
What is the protein family that this protein belongs to?
Belongs to the UPF0349 family.
Protein: HUTU_SHEB9
Sequence: MDKRHDPSRRIIAPHGTQLSCKSWLTEAPMRMLMNNLHPDVAERPEDLVVYGGIGRAARDWDCYDKIIEVLQRLEDDETLLVQSGKPVGVFRTHADAPRVLIANSNLVPHWANWEHFNELDKLGLAMYGQMTAGSWIYIGTQGIVQGTYETFVSVAKQHFDGISKGKWILTGGLGGMGGAQTLAGTMAGFSVLACEVDETRIDFRLRTRYVDKKATSLDEALAMIEEANQAGKPVSVGLLANAADVFAELVKRGVTPDVVTDQTSAHDPLNGYLPQGWTMAEAAAMRKTDEAAVIKAAKASMAVQVQAMLDLQTAGAATLDYGNNIRQMAFEMGVENAFDFPGFVPAYIRPLFCEGIGPFRWVALSGDPEDIYKTDAKVKELIPDNPHLHNWLDMARERIAFQGLPARICWVGLKDRARLALAFNEMVKNGELSAPVVIGRDHLDSGSVASPNRETESMLDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHSGVVIVCDGTDAAAKRVGRVLWNDPATGVMRHADAGYEIAKNCAKEQGLDLPMQD
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURE_STRPG
Sequence: MITIEQLLDILKKDHNFREVLDADGYHYHYQGLSFERLSYDSRQVDGKTLFFAKGATFKADYLKEAITNGLQLYISEVDYELGIPVVLVTDIKKAMSLIAMAFYGNPQEKLKLLAFTGTKGKTTAAYFAYHMLKESYKPAMFSTMNTTLDGKTFFKSQLTTPESLDLFAMMAECVTNGMTHLIMEVSSQAYLVDRVYGLTFDVGVFLNISPDHIGPIEHPTFEDYFYHKRLLMENSRAVVINSGMDHFSFLADQVADQEHMFYGPLSDNQITTSQAFSFEAKGQLAGHYDIQLIGHFNQENAMAAGLACLRLGASLADIQKGIAKTRVPGRMEVLTMTNHAKVFVDYAHNGDSLEKLLSVVEEHQTGKLMLILGAPGNKGESRRADFGRVIHQHPNLTVILTADDPNFEDPEDISQEIASHIARPVEIISDREQAIQKAMSLCQGAKDAVIIAGKGADAYQIVKGQQVAYAGDLAIAKHYL
What is the function of this protein?
Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase, L-lysine-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:L-Lys ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2342_BACCN
Sequence: MLSHELIERINFLARKAKNEGLTEEEQRERQSLREQYLKGFRQNMLNELKGIKIVNEEGKDITPAKLKALKKKNNVKLN
What are the official names of this protein?
UPF0291 protein Bcer98_2342.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPAR6_RAT
Sequence: MVSANGSHCPYDDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICALKVRNETTTYMINLAMSDLLFVFTLPFRIFYFATRNWPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCIAVWFTVMGGSAPAVFFQSTHSQGNNTSEACFENFPAATWKTYLSRIVIFIEIVGFFIPLILNVTCSSMVLRTLNKPVTLSRSKMNKTKVLKMIFVHLVIFCFCFVPYNINLILYSLVRTQTFVNCSVGAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQNSIKMKSWSVRRSDSRFSEVQGTENFIQHNLQTLKNKIFDNESAI
What is the function of this protein?
Binds to oleoyl-L-alpha-lysophosphatidic acid (LPA).  Intracellular cAMP is involved in the receptor activation.  Important for the maintenance of hair growth and texture (By similarity).
What are the official names of this protein?
Lysophosphatidic acid receptor 6, LPA receptor 6, LPA-6, Oleoyl-L-alpha-lysophosphatidic acid receptor, P2Y purinoceptor 5, P2Y5, Purinergic receptor 5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DXS_XANAC
Sequence: MIDTTRYPRLSRIQTPDDLRRFDEAELTAIAEELRSYLIESVGKSGGHFAAGLGVIELTVALHYLYQTPVDQLVWDVGHQTYPHKILTGRRDQIHTVKQKDGVAPFPKREESIYDTFGVGHSSTSISAALGMAIAAQRNGDDRKVVAVIGDGAMTAGMVYEALNHAGGMDPEPNLLVILNDNRMSISEAVGGLTKMLGRASGSRTLNAIREGGKKILGDKKNNPTARFVRRWEEHWKGMFVPSTLFEEMGFHYTGPIDGHDLPSLVGALKTLQTLKGPQLLHVITTKGKGYELAEGDQIGYHAVGPFDPSKGLVAKTGAKKPTYTDVFSDWVCDMAAAEPKLLVITPAMREGSGLVRFSKQYPQRYFDVAIAEQHAVTLAAGMATQGAKPVVAIYSTFLQRGYDQLVHDVAVQQLDVLFAIDRGGVVGPDGATHAGNLDLSFLRCVPHMVVMAPADEAECRQMLSTGVQYQGPAAVRYPRGTGPGAALDASLATLPIGKAQLRHSGTRIALLGFGATVDAAEAVGRELGLTVVNMRFVKPLDKALLLELAKTHDGFVTIEDNVVAGGAGSGVSELLNAEAITMPLLHLGLPDSFQHHASREDLLAEAGIDQAGIRAALLKRWPQLMISLPPALNAATG
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: SFSA_SULIA
Sequence: MKERDSRNQIGDLPFRVKEGFSVYEFIEQLYEANVVERINRFLVKVTFNGKEFLAHLHDPGRLKDLIYPGNLVLIRETKGYKTKFSITAAYSNSRFVVLDSRLHNIIASKFLPEAYEKEIKVGNSRIDFKYDNTYLEVKGCTLVENEIAYFPDAPTERGRRHLKELRELMKKGFNAILLILVMRDDAKCFLPNEKTDPKFSIEFWNSIKEGLNVNIKTFKLVGNKIIYVRDIPLCKTNLT
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: LEG6_CHICK
Sequence: MEQGLVVTQLDVQPGECVKVKGKILSDAKGFSVNVGKDSSTLMLHFNPRFDCHGDVNTVVCNSKEDGTWGEEDRKADFPFQQGDKVEICISFDAAEVKVKVPEVEFEFPNRLGMEKIQYLAVEGDFKVKAIKFS
What is the function of this protein?
This protein binds beta-galactoside.  Its physiological function is not yet known.  It may be involved in the regulation of differentiation.
What are the official names of this protein?
16 kDa beta-galactoside-binding lectin, C-16, Galectin CG-16.
Protein: SMUF1_HUMAN
Sequence: MSNPGTRRNGSSIKIRLTVLCAKNLAKKDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDPKWNQHYDLYVGKTDSITISVWNHKKIHKKQGAGFLGCVRLLSNAISRLKDTGYQRLDLCKLNPSDTDAVRGQIVVSLQTRDRIGTGGSVVDCRGLLENEGTVYEDSGPGRPLSCFMEEPAPYTDSTGAAAGGGNCRFVESPSQDQRLQAQRLRNPDVRGSLQTPQNRPHGHQSPELPEGYEQRTTVQGQVYFLHTQTGVSTWHDPRIPSPSGTIPGGDAAFLYEFLLQGHTSEPRDLNSVNCDELGPLPPGWEVRSTVSGRIYFVDHNNRTTQFTDPRLHHIMNHQCQLKEPSQPLPLPSEGSLEDEELPAQRYERDLVQKLKVLRHELSLQQPQAGHCRIEVSREEIFEESYRQIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNIYMLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITPVLDHTFCVEHNAFGRILQHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKELELIIGGLDKIDLNDWKSNTRLKHCVADSNIVRWFWQAVETFDEERRARLLQFVTGSTRVPLQGFKALQGSTGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEETCGFAVE
What is the function of this protein?
E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway.  Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway.  Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA.  Promotes ubiquitination and subsequent proteasomal degradation of MAVS (PubMed:23087404).  Acts as an antagonist of TGF-beta signaling by ubiquitinating TGFBR1 and targeting it for degradation (PubMed:21791611).  Plays a role in dendrite formation by melanocytes (PubMed:23999003).
What are the official names of this protein?
E3 ubiquitin-protein ligase SMURF1, hSMURF1, HECT-type E3 ubiquitin transferase SMURF1, SMAD ubiquitination regulatory factor 1, SMAD-specific E3 ubiquitin-protein ligase 1.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side.