PharMolix/UniProtQA huggingface dataset:
Protein: HXB1_CYPCA
Sequence: MDNSSMNSFLEYTICNRGTNAYSPKAGYQHLDQALSGPFHTGHARYSHNADGRLYIGGSNQPAAAQHQHQSGVYAHHQHQTHQSGIGLTYGGTGTTSYGTQACANPDYAQHQYFINPEQDGMYYHSSGFSNSNLGPHYGSMAGAYCGAQGAVPAAPYQHHGCEGQDHQRGYSQGTYADLSRSQGRERDTDQSPPGKTFDWMKVKRNPPKTAKVADYGLGPQNTIRTNFTTKQLTELEKEFHFSKYLTRARRVEIAATLELNETQVKIWFQNRRMKQKKREKEGLAPASSTLSKDLEDHSDHSTSTSPGASPSPDS
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.  Acts on the anterior body structures (By similarity).
What are the official names of this protein?
Homeobox protein Hox-B1.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family. Labial subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TFS2_MIMIV
Sequence: MTTVIEFYISDKEREIVIEQLLEFFPKKKNCKDIEKGIYDFTKQYCKSDNSYLRLAQAIYIDCAKNIMFNLKDENNHTIKKIKKLIDKNKYNAYNLAFLNPEELNKDNWIKIIARKQMTEETLNQMATVEWKPCYACKNTSYHFYQLQTRSADEPMTTFYICKNCMKTYKVNN
What are the official names of this protein?
Transcription factor S-II-related protein.
What is the protein family that this protein belongs to?
Belongs to the TFS-II family.
Protein: KC1_PLAYO
Sequence: MEIRVANKYALGKKLGSGSFGDIYVAKDIVTMEEFAVKLESTRSKHPQLLYESKLYKILGGGIGVPKVYWYGIEGDFTIMVLDLLGPSLEDLFTLCNRKFSLKTVLMTADQMLNRIEYVHSKNFIHRDIKPDNFLIGRGKKVTLIHIIDFGLAKKYRDSRSHTHIPYKEGKNLTGTARYASINTHLGIEQSRRDDIEALGYVLMYFLRGSLPWQGLKAISKKDKYDKIMEKKISTSVEVLCRNTSFEFVTYLNYCRSLRFEDRPDYTYLRRLLKDLFIREGFTYDFLFDWTCVYASEKDKKKMLENKNRFDQIADQEGRVKQN
What is the function of this protein?
Serine/threonine-protein kinase likely to be involved in many cellular processes.
What are the official names of this protein?
Casein kinase I.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
Protein: RL35_VIBPA
Sequence: MPKMKTNKGAAKRFKKTAGGIKYKHATKRHILTKRTTKNKRQLRPNAILPRCEVAAVIRMLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: SRY_PHYMC
Sequence: MFRIVNGEDYSPAVQQRNILDFGKAPSLLWTDNGSSNDRCDTGGNGRESGQDRVKRPMNAFIVWSRDQRRKVALENPQMQNSEISKRLGYDWKMLTEAEKQPFFEEAQRLRAMHRDKYPGYKYHPRRKPKRPQESLPADSSVLCSRTHIEETLYPFTYKDGCAKATRSRMESQLSHSQPTNISSSLLPQEHRSSWTILRHNRVTQATQTCGRPLLL
What is the function of this protein?
Transcriptional regulator that controls a genetic switch in male development.  It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.  Involved in different aspects of gene regulation including promoter activation or repression.  Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.  SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.  Also involved in pre-mRNA splicing (By similarity).  In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
What are the official names of this protein?
Sex-determining region Y protein, Testis-determining factor.
What is the protein family that this protein belongs to?
Belongs to the SRY family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Nucleus.
Protein: MNMC_BURP1
Sequence: MTDRIVPATLVFREDGTVVSPLYGDIYHSAAGALAQADHVFIRGNGLPERWRHERAFTIIETGFGTGCNFLATWAAWRADPSHCERLHFVSVEKHPFAREDLRRAAAHIVAYTTITTITPIAPLVDELANAWPALTPGVHRLEFDDGRVTLTLVFGDALDVLPNLALRAHAFYLDGFAPSKNADLWSPAIFKSLAKLADERATFATYTSSGAVKRALDEAGFAYRKVDGFAGKRAMLVGEFAPRWRVRRHEPPRAFSTDRRDAIVIGAGLAGCAVVERLAARGWHVTLIERRERIASEASGNPAGVFHPMIARDDNLAARLSRAGFLHALHRWRALERAGHAFSRSTHGLVQLATSDDEFERMRESIDALGVPAELASALSRDDARALLRTDVAHGGWLFAQGGSISPAALAAAQCAAAGDRLSRIVGVEIARLERGGDGRWRALDASGATIAQASVVVVANAADAARIAGLRHAPTQRVRGQLTLLPPGSAPAVPLPVIGDGYVVPLANGVTLTGATYEPDDTDATPREAGHRENLERLERLLPAFSANALDAGALAGRVGFRCVASDRLPLVGELGDEAAAAREAAALTGARLRDVPRATGLYGAFGYGSRGLVWATLGAELIAAQIDGEPWPLERELAEAIDPARFLVRALRHGRVA
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRYP_CRYPA
Sequence: MQFSIIAISFLASLAMASPAKRGGGGGGSGSGSGSGSGSGSGGGSTTYTACSSTLYSEAQCCATDVLGVADLDCETVPETPTSASSFESICATSGRDAKCCTIPLLGQALLCQDPVGL
What is the function of this protein?
Contributes to surface hydrophobicity, which is important for processes such as association of hyphae in reproductive structures, dispersal of aerial spores and adhesion of pathogens to host structures.  Produced abundantly, except in the ds-RNA virus-infected strains, where the expression is much reduced.
What are the official names of this protein?
Cryparin.
What is the protein family that this protein belongs to?
Belongs to the cerato-ulmin hydrophobin family.
What are the subcellular locations of this protein?
Secreted, cell wall. Secreted. Note=Cell wall of aerial hyphae and sporulation structures. Abundantly secreted.
Protein: AROC_STAA3
Sequence: MRYLTSGESHGPQLTVIVEGVPANIEIKVEDINKEMFKRQGGYGRGRRMQIEKDTVEIVSGVRNGYTLGSPITMVVTNDDFTHWRKIMGAAPISEEERENMKRTITKPRPGHADLVGGMKYNHRDLRNVLERSSARETAARVAVGALCKVLLQQLDIDIYSRVVEIGGIKDKDFYDSETFKANLDRNDVRVIDDSIAQAMRDKIDEAKNEGDSIGGVVQVVVENMPVGVGSYVHYDRKLDGKIAQGVVSINAFKGVSFGEGFKAAEKPGSEIQDEILYNSEIGYYRGSNHLGGLEGGMSNGMPIIVNGVMKPIPTLYKPLNSVDINTKEDFKATIERSDSCAVPAASIVCEHVVAFEIAKALLEEFQSNHIEQLKQQIIERRQLNIEF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: JOS1_PONAB
Sequence: MSCVPWKGDKAKSESLELPQAAPPQIYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIFQRLSPNTMVTPHKKSMLGNGNYDVNVIMAALQTKGYEAVWWDKRRDVGVIALTNVMGFIMNLPSSLCWGPLKLPLKRQHWICVREVGGAYYNLDSKLKMPEWIGGESELRKFLKHHLRGKNCELLLVVPEEVEAHQSWRTDV
What is the function of this protein?
Deubiquitinates monoubiquitinated probes (in vitro).  When ubiquitinated, cleaves 'Lys-63'-linked and 'Lys-48'-linked poly-ubiquitin chains (in vitro), hence may act as a deubiquitinating enzyme.  May increase macropinocytosis and suppress clathrin- and caveolae-mediated endocytosis.  May enhance membrane dynamics and cell motility independently of its catalytic activity (By similarity).
What are the official names of this protein?
Josephin-1, Josephin domain-containing protein 1.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm. Note=Ubiquitination increases localization the plasma membrane. In the cytosol, the unubiquitinated form may be associated with the cytoskeleton via ACTB-binding.
Protein: AMIS_MYCSM
Sequence: MGGVGLFYVGAVLIIDGLMLLGRISPRGATPLNFFVGGLQVVTPTVLILQSGGDAAVIFAASGLYLFGFTYLWVAINNVTDWDGEGLGWFSLFVAIAALGYSWHAFTAEADPAFGVIWLLWAVLWFMLFLLLGLGHDALGPAVGFVAVAEGVITAAVPAFLIVSGNWETGPLPAAVIAVIGFAAVVLAYPIGRRLAAPSVTNPPPAALAATTR
What is the function of this protein?
Possible transporter that might be responsible for the adsorption of amidase substrates or release of their hydrolysis products.
What are the official names of this protein?
Putative amidate substrates transporter protein.
What is the protein family that this protein belongs to?
Belongs to the AmiS/UreI family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RUVC_AFIC5
Sequence: MISRTIRILGIDPGLRRTGWGVIDVEGNRLIFVACGTVESRESLPLSERLLAIHEGLVRVVSEHRPLEAAVEQTFVNKDGAGTLKLGQARGVAMLVPAMSGISVAEYAPNLVKKTVVGAGHADKNQIQVMLKILLPKAAPPTPDAADALAIAITHAHHRQSAMLLRKVAAL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: DEOB_RHILO
Sequence: MARAFLFVLDSFGIGGAADAERYGDAGANTLAHIAEACAEGRADRERLRQGPLFVPHMASLGLGKAAETATGLGFAHFGTDLIANAFHGAAQEVSSGKDTPSGHWEIAGLPVRFDWGYFPDTVPAFPADLTAAMIREGEVPGILGNCHAPGTEIIERFGEEHIRTGKPICYTSVDSVLQIAAHEVHFGLDRLYEFCQVVRRLVDPLRIGRVIARPFVGETAATFQRTYNRHDYAVPPPEPTLLDRLTARGSRVIAVGKIGDIFAHRGISEVRKAAGNMAMFDKALGAMDDAGDGDLVFANFVDFDTEFGHRRDVAGYAAALEAFDRRLPEAFARLRQGDLLILTADHGNDPTWRGTDHTRERIPVIGMGPGLAGGDIGLRTTFADIGETVAEHLGLAPGRHGTSFHAMIGGHA
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADA_RAT
Sequence: MAQTPAFNKPKVELHVHLDGAIKPETILYYGKKRGIDLPADTVEGLRNIIGMDKPLSLPDFLAKFDYYMPAIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVDPIPWNQAEGDLTPDEVVDLVNQGLQEGEQAFGIKVRSILCCMRHQPSWSPEVLELCKKYHQKTVVAMDLAGDETIEGSSLFPGHVEAYEGAVKDGIHRTVHAGEVGSAEVVREAVDILKTERVGHGYHTIEDEALYNRLLKENMHFEVCPWSSYLTGAWNPKTTHAVVRFKDDQANYSLNSDDPLIFKSTVDTDYQMVKKDMGFTEEEFKRLNINAAKSSFLPEDEKKELLERLYKEYQ
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine (PubMed:19900420).  Plays an important role in purine metabolism and in adenosine homeostasis.  Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events.  Acts as a positive regulator of T-cell coactivation, by binding DPP4.  Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion.  Enhances dendritic cell immunogenicity by affecting dendritic cell costimulatory molecule expression and cytokines and chemokines secretion.  Enhances CD4+ T-cell differentiation and proliferation.  Acts as a positive modulator of adenosine receptors ADORA1 and ADORA2A, by enhancing their ligand affinity via conformational change.  Stimulates plasminogen activation.  Plays a role in male fertility.  Plays a protective role in early postimplantation embryonic development.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Extracellular side. Cell junction. Cytoplasmic vesicle lumen. Cytoplasm. Lysosome. Note=Colocalized with DPP4 at the cell surface.
Protein: DNLI_MONPV
Sequence: MTSLREFRKLCCDIYHASGYKEKSKLIRDFITDRDDTDTYLIIKLLLPGLDDRMYNMNDKQIIKLYSIIFKQSQEDMLQDLGYGYIGDTIRTFFKENTEIRPRDKSILTLEEVDSFLTTLSSVTKESHQIKLLTDIASVCTCNDLKCVVMLIDKDLKIKAGPRYVLNAISPHAYDVFRKSNNLKEIIENAAKQNLDSISISVMTPINPMLAESCDSVNKAFKKFPSGMFAEVKYDGERVQVHKKNNEFAFFSRNMKPVLSHKVDYLKEYIPKAFKKATSIVLDSEIVLVDEHNVPLPFGSLGIHKKKEYKNSNMCLFVFDCLYFDGFDMTDIPLYERRSFLKDVMVEIPNRIVFSELTNISNESQLTDVLDDALTRKLEGLVLKDINGVYEPGKRRWLKIKRDYLNEGSMADSADLVVLGAYYGKGGKGGIMAVFLMGCYDDESGKWKTVTKCSGHDDNTLRVLQDQLTMVKINKDPKKIPEWLVVNKIYIPDFVVDDPKQSQIWEISGAEFTSSKSHTANGISIRFPRFTRIREDKTWKESTHLNDLVNLTKSLNSYI
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.  Recruits cellular topoisomerase II to sites of viral replication and assembly.
What are the official names of this protein?
DNA ligase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: LEPA_KORVE
Sequence: MDRSFIRNFAIIAHIDHGKSTLSDRLLELTGSLTAREMQAQVLDAMDLERERGITIKAHSVRMMYKAHDDVVYQLNLIDTPGHVDFSYEVSRSLASCEGALLVVDASQGVEAQTLANAYLAINNGLEIIPVINKIDLPSADVERAKEMIEGAVGLDASHALPISAKTGMGVEDILESIVHLVPPPKGNPDHPLQALIFDSWFDSYRGVVILARIKEGTVRKGDKIMLWSNKHQFLVEEMGVLTPKPVAIEQLEAGEVGFIVANIKTVADVGIGDTITHVERPCLEALPGFEELKPMVFAGIYTVDAHEHTLLREALEKLRLNDSSFFFEPESSVALGFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPGVRYKITLTDNSVIEVDNPSKWPDSTLIEKIEEPIITAMILTNEEYVGGILKLVEEKRGRQKNFEYVTGSRVMLTYELPLNEIVLDFYDRLKSVSRGYASLDYHLAGAWESPMVKLDIMVAGESVDALSTIVHKDFAYDRGRALVSKMRELIPRQMFEVPIQAAIGAKIIARETVAAMRKNVLAKCYGGDISRKRKLLEKQKEGKKRMKRIGKVDIPQEAFLAVLKVGENS
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ILVD_BUCSC
Sequence: MPKYRSSTTTQGRNMAGARALWKATGMTDSDFNKPIIAVVNSFTEFVPGHIHLKELGTLVSSIIKLEGGVAKEFNTIAIDDGIAMGHSGMLYSLPSRELIADSIEYMINAHCADAMICISNCDKITPGMLMAALRLNIPCVFVSGGPMESGRIVVDGKEIKINLVDAIVYGANPNYSDALASRIENCACPTCGSCSGLFTANSMNCLTEALGLSLPGNGTLLATHIDRKKLFIDSGKLIVKITKEYYEDNNTSFLPRSIASRESFLNAMSLDISTGGSTNTILHLLAMAQEGQVDFKMSDIDLLSRKIPNLCKIAPNSDVYHMEDFHRAGGVIGLLAELNRVSLLNNNVKNILGLSLDVVLNKYDILKTKNQDVIEMFHAGPLGNKTSIPFTQSYRWKSLDKDRKKGCIRSYENAFSYDGGLAILYGNIAKNGCVVKTAGVKKGNLIFEGFAIVFESQEEALKAILENKVKKGHVVVIRYEGPKGGPGMQEMLYPTTYLKSMNLDEHCALITDGRFSGGTSGLSIGHISPEAANKGNIALIRNNDVININIPNRTINLDITNDEFLNRMHNEIQRGKSSYTPQFRKRFVSSALKMYALFATSADKGAVRKIQY
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: THII_PSEAE
Sequence: MKLIVKTFQEITIKSRPVRKRFIRQLAKNIRAVLRDLDPELKVEGEWDNLEVETAVVDAKARREMIERLTCTPGIGHFLEVHEYPLGDFDDILAKCKAHFGDQLAGKTFAVRCKRAGKHAFTSMEVERYVGSGLRRECGAAGIDLKQPEVEVRMEIRLDRLFVIHRQHPGLGGYPLGALEQVLVLMSGGFDSTVAAYQMMRRGMISHFVFFNLGGRAHELGVMEVAHYLWEKYGRSQRVLFVSVPFEEVVGEILTKVDDSYMGVTLKRMMLRAASRVAERLELDALVTGEAISQVSSQTLPNLSVIDRVTDTLVLRPLIVSHKQDIIDTARQIGTAEFARHMPEYCGVISVNPTTQAKPYRVEHEESKFDMAVLERALERATQRTVDRVIDELGQDLQVEEVGEVLPGQIVIDIRHPDAQEDEPLALEGVEVQALPFYAINSRFKELDANRQYLLYCDKGVMSRLHAHHLLNEGHTNVRVYRPA
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTFX2_ECOLI
Sequence: MALIVEFICELPNGVHARPASHVETLCNTFSSQIEWHNLRTDRKGNAKSALALIGTDTLAGDNCQLLISGADEQEAHQRLSQWLRDEFPHCDAPLAEVKSDELEPLPVSLTNLNPQIIRARTVCSGSAGGILTPISSLDLNALGNLPAAKGVDAEQSALENGLTLVLKNIEFRLLDSDGATSAILEAHRSLAGDTSLREHLLAGVSAGLSCAEAIVASANHFCEEFSRSSSSYLQERALDVRDVCFQLLQQIYGEQRFPAPGKLTQPAICMADELTPSQFLELDKNHLKGLLLKSGGTTSHTVILARSFNIPTLVGVDIDALTPWQQQTIYIDGNAGAIVVEPGEAVARYYQQEARVQDALREQQRVWLTQQARTADGIRIEIAANIAHSVEAQAAFGNGAEGVGLFRTEMLYMDRTSAPGESELYNIFCQALESANGRSIIVRTMDIGGDKPVDYLNIPAEANPFLGYRAVRIYEEYASLFTTQLRSILRASAHGSLKIMIPMISSMEEILWVKEKLAEAKQQLRNEHIPFDEKIQLGIMLEVPSVMFIIDQCCEEIDFFSIGSNDLTQYLLAVDRDNAKVTRHYNSLNPAFLRALDYAVQAVHRQGKWIGLCGELGAKGSVLPLLVGLGLDELSMSAPSIPAAKARMAQLDSRECRKLLNQAMACRTSLEVEHLLAQFRMTQQDAPLVTAECITLESDWRSKEEVLKGMTDNLLLAGRCRYPRKLEADLWAREAVFSTGLGFSFAIPHSKSEHIEQSTISVARLQAPVRWGDDEAQFIIMLTLNKHAAGDQHMRIFSRLARRIMHEEFRNALVNAASADAIASLLQHELEL
What is the function of this protein?
Multifunctional protein that includes general (non sugar-specific) and sugar-specific components of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS).  This major carbohydrate active transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II FrwABC PTS system is involved in fructose transport.
What are the official names of this protein?
Multiphosphoryl transfer protein 2, MTP 2, Triphosphoryl transfer protein 2, TTP 2.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BLAT_ECOLX
Sequence: MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
What is the function of this protein?
TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins.  TEM-3 and TEM-4 are capable of hydrolyzing cefotaxime and ceftazidime.  TEM-5 is capable of hydrolyzing ceftazidime.  TEM-6 is capable of hydrolyzing ceftazidime and aztreonam.  TEM-8/CAZ-2, TEM-16/CAZ-7 and TEM-24/CAZ-6 are markedly active against ceftazidime.  IRT-4 shows resistance to beta-lactamase inhibitors.
What are the official names of this protein?
Beta-lactamase TEM, IRT-4, Penicillinase, TEM-1, TEM-16/CAZ-7, TEM-2, TEM-24/CAZ-6, TEM-3, TEM-4, TEM-5, TEM-6, TEM-8/CAZ-2.
What is the protein family that this protein belongs to?
Belongs to the class-A beta-lactamase family.
Protein: RL362_YERPE
Sequence: MQVLSSLRSAKNRHPDCKIVRRRGRVYVICKSNPRFKAVQGGTHKKR
What are the official names of this protein?
50S ribosomal protein L36 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: CRGN_RAT
Sequence: MAQRSGKITLYEGKHFTGRKLEVFGDCDNFQDRGFMNRVNSIRVESGAWVCFDHPDFRGQQFILEHGDYPEFFRWNGHNDHMGSCRPVGMHGEHFRIDIFEGCNFTGQCLEFVEDCPFLQSRGWAKSCVNAIKVYGDGAWVLYEEPNYRGRMYVVERGDFRSFSDWEAHSARVQSLRRVLNFF
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.  Also plays an important role for integrity and function of auditory nuclei.
What are the official names of this protein?
Gamma-crystallin N, Gamma-N-crystallin.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: UTP25_MOUSE
Sequence: MGKRRNRGRSQMLSTMTKKQKKHLRDFGEEHPFYDRVSKKEAKPQICQLPESSDSSHSESESESEQEHVSGYHRLLATLKNVSEEEEEEEEEEEEEEEEEEEEEEEEEDDSAVGDAEMNEEAGSEDGSVGEAAVSEAAEEAAETQEHMSLADNSKEKDGEEPPGVSQKSSEEFTDVKHESLFSLETNFLEEDSGGSCSQRPSQDPFQQHVNKELKEKEIQAAASSPPATQQLKWPVLGHLVFSSKFQKTETFKPPKDIDLKLLHLQKPLESTWAKTNSQFLSGPQKSNSSFTPLQKELFLIMNSYRDLFYPERTALKNGEEVRHVYCLHAINHVLKANAQVLANNSRRRSQKLGVGEDDDFRDQGLTRPKVLIVVPFREAALRVVQLFISLLEGDSKKKIIVSNKKRFQGEYGSDPEERPPNLKRPEDYEAVFVGNIDDHFRIGVAILQRSIRLYAPFYSSDILIASPLGLRTIIGGEGEKKRDFDFLSSVELLIIDQADIYLMQNWEHVLHLMNHMNLLPLDSHGVDFSRVRMWSLNNWSKYYRQTLLFGALQDAQINSVFNKHCINAQGQVAVRNVPMTGSISHVLVQLPHVFQRMEAQDLSSVIDARFHFFINKILPQYRDAVMSHTLIYVPSYFDFVRLRNYFKKEELNFTHICEYTQKSGISRARHFFLQGEKQFLLLTERFHFYKRYTIKGIRNLIFYELPTYPHFYSEVCNMLRATSRGEEATWTCTVLYSKYDAQRLAAVVGVERAAQMLQSPKNVHLFVTGEK
What is the function of this protein?
Component of the ribosomal small subunit processome for the biogenesis of ribosomes, functions in pre-ribosomal RNA (pre-rRNA) processing (By similarity).  Essential for embryonic development in part through the regulation of p53 pathway.  Controls the expansion growth of digestive organs and liver (PubMed:29262616, PubMed:32303961).  Also involved in the sympathetic neuronal development (By similarity).  Mediates, with CAPN3, the proteasome-independent degradation of p53/TP53 (By similarity).
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 25 homolog, Digestive organ expansion factor homolog, UTP25 small subunit processor component.
What is the protein family that this protein belongs to?
Belongs to the UTP25 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CSOCA_PROMM
Sequence: MAYRNRNLASQTQRPLAPTAPRRRPVVTPQISDRSRLRGFANVGSGPCHPLTDRAANQHLQTYEANVKGSFELIVPFLKRISALQHDQDFVSKCQSLARSELGFDLPSHLLEQAWVRALDMRALFAWCVFQSHQHVSDHFFQEDPLQGGEGSIQAKHFQSFLVDCGFHLLDVSPCADGRLAHTIAYALRIPFSSVRRRSHAGALFDVEKTVNRWIKTEHRRYREGVPNSADSPTRYLKVVTYHFSSLDPSHQGCAAHGSDDALAASAGQQRLLDFRESVENSFCCGASVDLLLIGLDTDTDAIRVHVPAADGSIVLDEWLSAEDLYHETLSLTSDEAMQHIAERVEAIAPKKPDEGMVAFIVKLIANNFSQIDYVKQSHAGPYPDAGHAERFIGVGIGFKEVHLRNLTYFAHLDTVEVGAPDLDVGVKIFKGLNVSRDLPIPVVVRFDYSGQVPGARDRAVTDCYRVNQAIAERYSELFDQGLLHTFLTIRDRDKKDTSEVVGSSLEPVHQEAH
What is the function of this protein?
Reversible hydration of carbon dioxide (PubMed:14729686).  Essential for photosynthetic carbon dioxide fixation, supplies CO(2) to RuBisCO (ribulose bisphosphate carboxylase, cbbL-cbbS) in the carboxysome (Probable).
What are the official names of this protein?
Carboxysome shell carbonic anhydrase, CsoSCA, Carbonic anhydrase, CA, Carboxysome shell protein CsoS3.
What is the protein family that this protein belongs to?
Belongs to the beta-class carbonic anhydrase family. CsoSCA subfamily.
What are the subcellular locations of this protein?
Carboxysome. Note=This cyanobacterium makes alpha-type carboxysomes.
Protein: RPOZ_AZOC5
Sequence: MARVTVEDCIDKVDNRFELVLLAGHRARMISSGSPITVDRDNDKNPVVALREIADETVSPEDLKEDLIHSLQKYTEVDEPEPESVPLIASSEGGVDDADIVLDRMTEEELLAGLQGLVPPEQTDDDEG
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.