PharMolix/UniProtQA huggingface dataset:
Protein: CH10_CLOK5
Sequence: MKIRPLGDRVVIKKIEAEETTKSGIVLPGSAKEKPQEAEIVAVGPGGVIDGKEIKMEVKVGDRVLFSKYAGNEVKIDGVEYTILRQDDILAIIE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYD_STRA5
Sequence: MKRSMYAGRVRSEHIGTSITLKGWVGRRRDLGGLIFIDLRDREGIMQLVINPEEVSASVMATAESLRSEFVIEVSGVVTAREQANDNLPTGEVELKVQELSILNTSKTTPFEIKDGIEANDDTRMRYRYLDLRRPEMLENFKLRAKVTHSIRNYLDNLEFIDVETPMLTKSTPEGARDYLVPSRVNQGHFYALPQSPQITKQLLMNAGFDRYYQIVKCFRDEDLRGDRQPEFTQVDLETSFLSDQEIQDIVEGMIAKVMKDTKGLEVSLPFPRMAYDDAMNNYGSDKPDTRFDMLLQDLTEIVKEVDFKVFSEASVVKAIVVKDKADKYSRKNIDKLTEIAKQYGAKGLAWLKYADNTISGPVAKFLTAIEGRLTEALQLENNDLILFVADSLEVANETLGALRTRIAKELELIDYSKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPTAETAHELEGDLAKVRAVAYDIVLNGYELGGGSLRINQKDTQERMFKALGFSAESAQEQFGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLVSEQQLEELSLTVESYEN
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNU71_YEAST
Sequence: MRDIVFVSPQLYLSSQEGWKSDSAKSGFIPILKNDLQRFQDSLKHIVDARNSLSETLLNSNDDGSIHNSDQNTGLNKDKEASIADNNSANKCATSSSRYQELKQFLPISLDQQIHTVSLQGVSSSFSRGQIESLLDHCLNLALTETQSNSALKVEAWSSFSSFLDTQDIFIRFSKVDEDEAFVNTLNYCKALFAFIRKLHEDFKIELHLDLNTKEYVEDRTGTIPSVKPEKASEFYSVFKNIEDQTDERNSKKEQLDDSSTQYKVDTNTLSDLPSDALDQLCKDIIEFRTKVVSIEKEKKMKSTYEESRRQRHQMQKVFDQIRKNHSGAKGSANTEEEDTNMEDEDEEDDTEDDLALEKRKEERDLEESNRRYEDMLHQLHSNTEPKIKSIRADIMSAENYEEHLEKNRSLYLKELLHLANDVHYDHHRSFKEQEERRDEEDRAKNGNAKELAPIQLSDGKAISAGKAAAITLPEGTVKSENYNADKNVSESSEHVKIKFDFKKAIDHSVESSSEDEGYRESELPPTKPSERSAAEDRLPFTADELNIRLTNLKESRYVDELVREFLGVYEDELVEYILENIRVNQSKQALLNELRETFDEDGETIADRLWSRKEFRLGT
What is the function of this protein?
Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA.  Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway.
What are the official names of this protein?
U1 small nuclear ribonucleoprotein component SNU71.
What is the protein family that this protein belongs to?
Belongs to the SNU71 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATPA_ACIET
Sequence: MQLNPAEISELIKSRIEGLAASSDIRNQGTVVSVTDGIVRVHGLSDVMQGEMLEFPAAADGQPSFGLALNLERDSVGAVILGEYEHISEGDTVKCTGRILEVPVGPELIGRVVNALGQPIDGKGPINAKMTDVIEKVAPGVIARQSVDQPLQTGLKSIDSMVPIGRGQRELIIGDRQTGKTAVAIDAIINQKGQGVTCIYVAIGQKASSIKNVVRALEQAGAMEYTIVVAASASESAAMQYVSAYSGCTMGEYFRDRGEDALIVYDDLSKQAVAYRQVSLLLRRPPGREAFPGDVFYLHSRLLERAARVNADYVEAFTKGEVKGKTGSLTALPVIETQAGDVSAFVPTNVISITDGQIFLETSLFNAGIRPAINAGISVSRVGGAAQTKLIKGLSGGIRTDLAQYRELAAFAQFASDLDEATRKQLDRGARVTELLKQPQYSPLSTALMGATLFTVNKGFLDDVDVKKVLAFEAGLHQYLKTSHGALLDRLQQNRAFDKEGKDEAELTQAITAFKKSFV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FOLB_STRP8
Sequence: MDKIVLEGCRFYGYHGAFKEEQTLGQIFLVDLELSVDLQAASLSDQLTDTVHYGMVFDSVRQLVEGEKFILIERLAGAICEQLFNEFPPIEAIKVAIKKENPPIAGHYKAVGIELERQR
What is the function of this protein?
Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
What are the official names of this protein?
Dihydroneopterin aldolase, DHNA, 7,8-dihydroneopterin aldolase.
What is the protein family that this protein belongs to?
Belongs to the DHNA family.
Protein: IVD_HUMAN
Sequence: MAEMATATRLLGWRVASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQLRQTMAKFLQEHLAPKAQEIDRSNEFKNLREFWKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMKLKAEKKGNHYILNGNKFWITNGPDADVLIVYAKTDLAAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGLDLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTAKDCAGVILYSAECATQVALDGIQCFGGNGYINDFPMGRFLRDAKLYEIGAGTSEVRRLVIGRAFNADFH
What is the function of this protein?
Catalyzes the conversion of isovaleryl-CoA/3-methylbutanoyl-CoA to 3-methylbut-2-enoyl-CoA as an intermediate step in the leucine (Leu) catabolic pathway (PubMed:7640268).  To a lesser extent, is also able to catalyze the oxidation of other saturated short-chain acyl-CoA thioesters as pentanoyl-CoA, hexenoyl-CoA and butenoyl-CoA (PubMed:7640268).
What are the official names of this protein?
Isovaleryl-CoA dehydrogenase, mitochondrial, IVD, Butyryl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
Protein: HPRL_HALLT
Sequence: MDQLRQSLLDAPIIEKGEYQYFVHPISDGVPMLKPELLREIVIRIIRKAELENVDKIVTPAAMGIHISTALSLMTDIPLVVIRKRQYGLDGEVPLFQETGYSESEMYINDVEEGDRVLVLDDVLSTGGTMKAILDALTDEVGAEVVDVVAVIKKAGENELDDTDYNVKTLINVTVEDGEVVIVDAKGDD
What is the function of this protein?
May catalyze a purine salvage reaction, the substrate is unknown.
What are the official names of this protein?
HGPRTase-like protein.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
Protein: METE1_ARATH
Sequence: MASHIVGYPRMGPKRELKFALESFWDGKSTAEDLQKVSADLRSSIWKQMSAAGTKFIPSNTFAHYDQVLDTTAMLGAVPPRYGYTGGEIGLDVYFSMARGNASVPAMEMTKWFDTNYHYIVPELGPEVNFSYASHKAVNEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVDKSFELLSLLPKILPIYKEVITELKAAGATWIQLDEPVLVMDLEGQKLQAFTGAYAELESTLSGLNVLVETYFADIPAEAYKTLTSLKGVTAFGFDLVRGTKTLDLVKAGFPEGKYLFAGVVDGRNIWANDFAASLSTLQALEGIVGKDKLVVSTSCSLLHTAVDLINETKLDDEIKSWLAFAAQKVVEVNALAKALAGQKDEALFSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSARLDAQQKKLNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKAIKEEIKKVVDLQEELDIDVLVHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAMTVFWSAMAQSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGGIGVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIHSIIDMDADVITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKMLAVLEQNILWVNPDCGLKTRKYTEVKPALKNMVDAAKLIRSQLASAK
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1, Cobalamin-independent methionine synthase 1, AtMS1, Vitamin-B12-independent methionine synthase 1.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: URK_YERP3
Sequence: MTDKAHQCVIIGIAGASASGKSLIASTLYRELREQVGDQHIGVIPEDGYYKDQSHLSMEERVKTNYDHPSAMDHNLLLEHLQALKAGKPVELPLYSYTEHTRKKETVHLEPKKVIILEGILLLTDIRLRQEMNFSIFVDTPLDICLMRRMKRDVNERGRSMDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COABC_VIBCH
Sequence: MQSLAGKKILLGISGGIAAYKCAELTRRLVERGATVQVVMTHAAKEFITPLTMQAVSGRPVSDSLLDPAAEASMGHIELAKWADLVLLAPATADLIARMAAGMGNDLLTTLILATSAPVAIAPAMNQQMYRNIATQENLQTLIRRGYLTWGPAAGEQACGDVGPGRMLEPMELVAHCENFFAPKILVGKRVLITAGPTREALDPVRYITNHSSGKMGFALAKAAAQLGADVTLVSGPVHLPTPVGVNRIDVQSGLEMHSAVMKEATSHQIFIACAAVADYRPQTVAEQKIKKSRDNDTLTIEMVKNPDIVASVAALTENRPFTVGFAAETQDVETYARSKLVRKNLDMICANDVSIAGQGFNSNDNALTLFWKEGQHSLPLTSKDALASAVMHLIHEQM
What is the function of this protein?
Catalyzes two sequential steps in the biosynthesis of coenzyme A.  In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine.  In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
What are the official names of this protein?
Coenzyme A biosynthesis bifunctional protein CoaBC, DNA/pantothenate metabolism flavoprotein, Phosphopantothenoylcysteine synthetase/decarboxylase, PPCS-PPCDC.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PPC synthetase family.
Protein: JDP2_MOUSE
Sequence: MMPGQIPDPSVTAGSLPGLGPLTGLPSSALTTEELKYADIRNIGAMIAPLHFLEVKLGKRPQPVKSELDEEEERRKRRREKNKVAAARCRNKKKERTEFLQRESERLELMNAELKTQIEELKLERQQLILMLNRHRPTCIVRTDSVRTPESEGNPLLEQLDKK
What is the function of this protein?
Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins.  Involved in a variety of transcriptional responses associated with AP-1, such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris.  Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN.  May control transcription via direct regulation of the modification of histones and the assembly of chromatin (By similarity).
What are the official names of this protein?
Jun dimerization protein 2.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. ATF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: R31B2_ECO57
Sequence: MKPNIHPEYRTVVFHDTSIDEYFRIGSTIKTDRVIELDGVTYPYVTIDVSSKSHPFYTGKLRTVASEGNVARFTQRFGRFVDAKKGG
What are the official names of this protein?
50S ribosomal protein L31 type B 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: RRAB_PANAM
Sequence: MAFEALLEEQREETRLIIEELLEDGSDPDALYTIEHHLSCNNFDSLEKAAVDAFKLGYEVTEPEELELEDGTTVMCVDILSEGALKAELIDAQVEQLVNLVAKYNVDYDGWGTYFEDPNAQDDDEDDGEAIDEDDNGIRH
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity B.
What is the protein family that this protein belongs to?
Belongs to the RraB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JUPIT_DROMO
Sequence: MATYAAFKHVELYNVGKAKKRVLRAPGGVSSDIFGSEQPQTPRNVKNLMASNIFSADTDAAQKNNVRQGAHRFYYIGETPRRGQKPVDSYSRLFGEPARPITPSKNHMKSNIPFGQNPNTAPLISKGNYNGKSGSVSSASSSVSSSTENLKINGGVRSEGNPVTGEGYKAGGTDYIQPAHLNGGSQVINKNRVPPGGYSSGLW
What is the function of this protein?
Binds to all microtubule populations.
What are the official names of this protein?
Microtubule-associated protein Jupiter.
What is the protein family that this protein belongs to?
Belongs to the MAP Jupiter family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle.
Protein: CH602_NITHX
Sequence: MSAKDVKFGVDARDKMLRGVDILANAVKVTLGPKGRNVVLEKSFGAPRITKDGVTVAKEIELEDKFENMGAQMVREVASKSADAAGDGTTTATVLAQAIVREGAKSVAAGMNPMDLKRGIDLAVEAVVADLVRNSKKVTSNDEIAQVGTISANGDSEIGKFLANAMKRVGNEGVITVEEAKSLETELDVVEGMQFDRGYISPYFVTNADKMRVEMDDAYILINEKKLSSLNELLPLLEAVVQTGKPLVIVAEDVEGEALATLVVNRLRGGLKVAAVKAPGFGDRRKAMLQDIAILTGGQAISEDLGIKLENVTLAMLGKAKKVMIDKENTTIVNGAGKKADIEARVAQIKAQIEETTSDYDREKLQERLAKLAGGVAVIRVGGATEVEVKERKDRVDDAMHATRAAVEEGIVPGGGVALLRASEQLKRIKTANDDQKTGVEIVRKALSAPARQIAINAGEDGSVIVGKILEKEQYSYGFDSQSGEYGNLISKGIIDPTKVVRAAIQNAASVAALLITTEAMVAELPKKNAGGPAMPAGGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOC3L_CRIGR
Sequence: MKARRNKKQVPSFRKLIKTSKVKLEYKLKNKQFKQQSTIKKYRKEQRKLRQAVKDAVSKKPFPLEDPKSKRPVKGMEREEEDEEDQALPLDMMDDDDLQLMKDLGQKASFLTRDLSSSEPVHIKKRKHESVIDKYEKMPRTLQTAPEKELIHLLPIKDKSGIIPQTREKPVTDIQQEEEDEEELEVEEEVVENPIQELTIEEHLIVRKKKLQEKKIQIATLASSILSDPESNIKKLKELRSMLMEQDPDVAVTVRKLVIISLMELFKDITPSYKIRPLTEAEKSTKIRKETQKLREFEEGLVSQYKFYLENLEQIVKDWKQRKLKKSNVVSLKAYKGLAEVAVKSLCELLVALPHFNFHNNIIVLIVPLMNDGSKLVSEMCCEAVKKLFKQDKLGQASLGVIKVISGFVKGRNYEVRPEMLKTFLCLRIKEVEVKKDTEDINKPKKFMTFKEKRKTLSRMQRKWKKAEEKLERELREAEASESTERKLKLHTETLNIVFVTYFRILKKAQRSPLLPAVLEGLAKFAHLINVEFFDDLLVVLHTLIESGDLSYQESLHCVQTAFHILSGQGDVLNIDPMKFYTHLYKTLFKLHAGATNDGIEIVLHCLDVMLSKRRKQVSHQRALAFIKRLCTLALQVLPNSSIGLLATTRILMHTFPRTDLLLDNESQGSGVFLPELEEPEYCNAQNTALWELHALRRHYHPVVQRFAVHLLAGAPSEGSEALKPELSRRSAVELFEAYSMAAMTFNPPVEPSNSKKKDKLLQGDSFLNEDLNQLIKRYCNEVTTEIPLDFTKCLKTSVQ
What are the official names of this protein?
Nucleolar complex protein 3 homolog, NOC3 protein homolog, NOC3-like protein, Nucleolar complex-associated protein 3-like protein.
What is the protein family that this protein belongs to?
Belongs to the CBF/MAK21 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: Y553_TREPA
Sequence: MEKQSPAQTISLFVLLALMFVLVCMLFVPYLTVLLWSSILAILLSPCYRALCARIDMHAFTRTRHLVSHMNGEDGCTAAITRATRFQKKMLAAVFSLVITLLVTTVFFFIAISLFGQGKLLFDKLSLFFREYDLFEGAKQRSFTALIFKLSRGTVDISTLNVEEHLLRFFGKHVESVFVYTQIFVKNIARAALSTLFFSFTLYFFFLDGEHLSCLLIAALPLRKRASAQLLEKCKEATRHLFKGLFSIAFYQTCVAFVFYGIFRVEGPMALAMLTFFASFLPLVGCACVWLPVGISIGFTSGWMRGTLFLFVAGSSITIIDSFLRPLLLQNKMRIHPLLIFFSMLGGVQTFGFNGMVLGPILVILLFTVIDLTHDGESHYTSIFHDPPAAGVHAQSIHRQGKK
What are the official names of this protein?
Putative transport protein TP_0553.
What is the protein family that this protein belongs to?
Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: P73_HUMAN
Sequence: MAQSTATSPDGGTTFEHLWSSLEPDSTYFDLPQSSRGNNEVVGGTDSSMDVFHLEGMTTSVMAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGPVLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSSHSAQSMVSGSHCTPPPPYHADPSLVSFLTGLGCPNCIEYFTSQGLQSIYHLQNLTIEDLGALKIPEQYRMTIWRGLQDLKQGHDYSTAQQLLRSSNAATISIGGSGELQRQRVMEAVHFRVRHTITIPNRGGPGGGPDEWADFGFDLPDCKARKQPIKEEFTEAEIH
What is the function of this protein?
Participates in the apoptotic response to DNA damage.  Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms.  May be a tumor suppressor protein.  Is an activator of FOXJ1 expression (By similarity).  It is an essential factor for the positive regulation of lung ciliated cell differentiation (PubMed:34077761).
What are the official names of this protein?
Tumor protein p73, p53-like transcription factor, p53-related protein.
What is the protein family that this protein belongs to?
Belongs to the p53 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Accumulates in the nucleus in response to DNA damage.
Protein: CYSC1_ARATH
Sequence: MASVSRRLLRRETIPCFSHTVRKLFSTVGSPSFAQRLRDLPKDFPSTNAKRDASLLIGKTPLVFLNKVTEGCEAYVAAKQEHFQPTCSIKDRPAIAMIADAEKKKLIIPGKTTLIEPTSGNMGISLAFMAAMKGYRIIMTMPSYTSLERRVTMRSFGAELVLTDPAKGMGGTVKKAYDLLDSTPDAFMCQQFANPANTQIHFDTTGPEIWEDTLGNVDIFVMGIGSGGTVSGVGRYLKSKNPNVKIYGVEPAESNILNGGKPGPHAITGNGVGFKPEILDMDVMESVLEVSSEDAIKMARELALKEGLMVGISSGANTVAAIRLAKMPENKGKLIVTIHASFGERYLSSVLFDELRKEAEEMKPVSVD
What is the function of this protein?
Acts as a major beta-cyanoalanine synthase.  The cyanoalanine synthesis reaction is more efficient than the cysteine synthase activity.  Probably unable to interact with SAT and to form the decameric Cys synthase complex (CSC) and is therefore not an enzymatically true OASTL protein.  Probably involved in the detoxification of cyanide that arises from ethylene biosynthesis.  Maintains a low level of cyanide for proper root hair development.
What are the official names of this protein?
Bifunctional L-3-cyanoalanine synthase/cysteine synthase C1, mitochondrial, Beta-substituted Ala synthase 3;1, ARAth-Bsas3;1, Cysteine synthase C1, AtCYSC1, O-acetylserine (thiol)-lyase 5.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
Protein: MUTH_HAEIN
Sequence: MIPQTLEQLLSQAQSIAGLTFGELADELHIPVPIDLKRDKGWVGMLLERALGATAGSKAEQDFSHLGVELKTLPINAEGYPLETTFVSLAPLVQNSGVKWENSHVRHKLSCVLWMPIEGSRHIPLRERHIGAPIFWKPTAEQERQLKQDWEELMDLIVLGKLDQITARIGEVMQLRPKGANSRAVTKGIGKNGEIIDTLPLGFYLRKEFTAQILNAFLETKSL
What is the function of this protein?
Sequence-specific endonuclease that cleaves unmethylated GATC sequences.  It is involved in DNA mismatch repair.
What are the official names of this protein?
DNA mismatch repair protein MutH, Methyl-directed mismatch repair protein.
What is the protein family that this protein belongs to?
Belongs to the MutH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANOI_ACINO
Sequence: MNIIAGFQNNFSEGLYSKFKSYRYKVFVEHLGWELNCPHNEELDQFDKVDTAYVVAQDRDSNIIGCARLLPTTQPYLLGEIFPQLLNGIPLPCSPEIWELSRFSAVDFSNPPTTASQAVSSPVSIAILQEAINFARAQGAKQLITTSPLGVERLLRAAGFRAHRAGPPMTIDGYSMFACLIDV
What is the function of this protein?
Involved in the synthesis of the acyl-homoserine lactone (AHL) signal N-(3-hydroxydodecanoyl)-L-HSL (3-hydroxy-C(12)-HSL or OH-dDHL).  Probably part of a quorum-sensing system with AnoR.
What are the official names of this protein?
Acyl-homoserine-lactone synthase, Autoinducer synthesis protein AnoI.
What is the protein family that this protein belongs to?
Belongs to the autoinducer synthase family.
Protein: FPG_RHIME
Sequence: MPELPEVETVKRGLAPTMEGALLVRAELRRPDLRFPFPENFANAVAGRRIIALSRRAKYLMIELEGGDVIIAHLGMSGSFRIEKGPIEAGADPATPGAFHHPRGKDEKHDHVVFHLDGGSGPARVIYNDPRRFGFMDLARRSALADHVFLRGLGEEPTGNALDAAYLATRFAGKIQPLKAALLDQRTIAGLGNIYVCEALWRSGLSPKRSAGTLVDKRGRPKQALIALTERIRAVIADAIAAGGSSLKDHIQADGSLGYFQHSFSVYDREGEACRTPGCHGTVARIVQAGRSTFYCPHCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: TPIS_ACET2
Sequence: MSRKVIAAGNWKMNKTPKEAVEFVQALKGRVADADTEVVVGVPFVCLPGVVEAAKGSNIKVAAQNMHWEEKGAFTGEVSGPMLAELGVDYVIIGHSERRQYFGETDETVNKKVHAAFKYGLKPIICVGESLTQREQGVTAELVRYQVKIALLGLSAEQVKEAVIAYEPIWAIGTGKTATNEQAEEVCGIIRECIKELYGQDVAEAIRIQYGGSVNAANAAELFNMPNIDGGLVGGASLKLDDFEKIAKYNK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MY117_ARATH
Sequence: MFITEKQVWMDEIVARRASSSWDFPFNDINIHQHHHRHCNTSHEFEILKSPLGDVAVHEEESNNNNPNFSNSESGKKETTDSGQSWSSSSSKPSVLGRGHWRPAEDVKLKELVSIYGPQNWNLIAEKLQGRSGKSCRLRWFNQLDPRINRRAFTEEEEERLMQAHRLYGNKWAMIARLFPGRTDNSVKNHWHVVMARKYREHSSAYRRRKLMSNNPLKPHLTNNHHPNPNPNYHSFISTNHYFAQPFPEFNLTHHLVNNAPITSDHNQLVLPFHCFQGYENNEPPMVVSMFGNQMMVGDNVGATSDALCNIPHIDPSNQEKPEPNDAMHWIGMDAVDEEVFEKAKQQPHFFDFLGLGTA
What is the function of this protein?
Probable transcription factor that involved in boundary specification, meristem initiation and maintenance, and organ patterning (PubMed:19542355, PubMed:21533201).  Functions in both lateral organ separation and axillary meristem formation, in part through genetic interaction with the NAC domain genes CUC2 and CUC3 and the homeobox gene STM (PubMed:19542355).  May be recruited by a variety of developmental programs for the development of floral organs and the initiation of ovule outgrowth (PubMed:21533201).
What are the official names of this protein?
Transcription factor MYB117, MYB-domain transcription factor LOF1, Myb-related protein 117, AtMYB117, Protein CONSTRICTED FRUIT, Protein LATERAL ORGAN FUSION 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL36_CHICK
Sequence: MAIRYPMAVGLNKGYKVTKNVSKPRHCRRRGRLTKHTKFVRDMIREVCGFAPYERRAMELLKVSKDKRALKFIKKRVGTHIRAKRKREELSNVLAAMRKAAAKKD
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL36 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Note=Detected on cytosolic polysomes.
Protein: GPMA_CUPTR
Sequence: MYKLVLIRHGESTWNLENRFTGWVDVDLTETGAAQARQAGKLLKEAGMGFDVAYTSVLKRAIRTLWHVQDEMDLMWIPVRNEWRLNERHYGALAGLNKSETAAKFGDEQVLVWRRSYDTPPPALEPTDPRASYDDPRYANVPRNEIPLTECLKDTVARVMPLWNESIAPDIQSGKRVVIAAHGNSIRALVKYLDQISDDDIVGLNIPNGTPLVYELDADLRPLRHYYLGDQEAIAASLAAVASQGKAR
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: RPO10_SULIL
Sequence: MMIPIRCFTCGSLIADKWQPFITRVNAGENPGKVLDDLGVKRYCCRRMLLSHIDIISEVIHYTRPI
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo10, DNA-directed RNA polymerase subunit N.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.