PharMolix/UniProtQA huggingface dataset:
Protein: VL1_HPV22
Sequence: MTLWLPTSGKIYLPPTPPVARVQNTDEYVERTDIYYHAISDRLLTVGHPYFDVRSSDGAKIEVPKVSGNQFRAFRVTFPDPNKFALGDMTIHDPERYRLVWACKGLEIGRGQPLGVGTTGHPLFNKLHDTENPTERQEGTSDDRRNVSFDPKQVQMFIIGCIPCLGEYWDKAPVCEDAGSQVGLCPPLELKNGVIEDGDMFDIGFGNINNKTLSFNRSDVSLDIVNEICKYPDFLTMSNDVYGDSCFFCARREQCYARHNFVRGGLVGDAIPDDAVQQDHKYYLPAASQTALENSTYFPTVSGSLVTSDAQLFNRPFWLKRAQGHNNGILWNNQMFVTVADNTRNTNFSISVASDGTTVNYDAKKIREFMRHVEEYQLSFILQLCRIPLEAEVLTQINAMNHGILENWQLGFVPTPDNSVHDTYRYLQSKATKCPDAVPDTQKEDPFGQYTFWNVDMSEKLSLDLDQYPLGRKFLFQSGLQRARASARVSVKRSATRKTSKTVKRRKLTS
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: ACCA_SYNY3
Sequence: MSKSERRVFLLDFEKPLYELEEKINQIRELAEEKNVDVSEQLSQLESRAEQLRQEIFSNLNPSQRLQLARHPRRPSTLDYIQAIADDWFEMHGDRGGYDDPALVGGVARLGTRPVVIMGHQKGRDTKDNVARNFGMAAPNGYRKALRLMEHADRFGMPIITFIDTPGAWAGIDAEKLGQGEAIAVNLREMFRLDVPILCTVIGEGGSGGALGIGVGDRVLMLENAVYTVATPEACAAILWKDAKKSDKAAIALKITADDLAKLQIIDGIIPEPKGAAHANPLGAAAKLKEALLFHLNTLAQLTPQERKQLRYDKFRHLGQFLETAV
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU3_CLAM3
Sequence: MPRTISLAVVPGDGIGPEVVHEALRVLREAVPADVSLDTTQYPFGAGHFLETGEILTDSDLAALAQHDAILLGAVGGDPRDARLAGGIIERGLLLKLRFAFDHYINLRPTTLLPGVTSPLASPGEVDFVVVREGTEGPYAGNGGVLRRGTEHEIATEVSVNTAHGVERTVRFAFDLASKRERKRVTLVHKTNVLTFAGSLWQRTVDRVAAEHPDVAVDYLHVDATMIFLVTDPSRFDVIVSDNLFGDIITDLAAAISGGIGLAASGNVNPTGAFPSMFEPVHGSAPDIAGQQKADPTAAILSVSLLLDHLGLPEAAARVTAAVSADLAARAAGDPAPRSTAEVGDAVIRALSTNH
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO3_THEKO
Sequence: MVEFKILEKRPDSIKFIVSGVDVPFANALRRTILSEVPTFAVDEVEFLENDSALFDEIIAHRLAMIPLTTPHERFSLDALELDDYTVTLSLEAEGPGMVYSGDLKSSDGDVKPANPNIPIVKLAEGQRLTFNAYARLGRGKDHAKWQPGFVYYKYLTKIHVSKDVPDWEELKELAERRGLPVEESDEEIVITTIKAFYLPRKFEEHMGKGIREEIVPGSFVFTVETNGELPVEEIVSIALKILMRKSDRFINELHKLAD
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo3, DNA-directed RNA polymerase subunit D.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFSA_SALTY
Sequence: MLFSPPLQRATLIQRYKRFLADVITPDGTTLTLHCPNTGAMTGCATPGDTVWYSTSENTKRKYPHTWELTETQSGAFICVNTLRANQLTKEAIQENRLPALAGYNILKSEVKYGAERSRIDFMLQADFRPDCYIEVKSVTLAEKENGYFPDAITERGQKHLRELMGVAAAGHRAVVVFAVLHSAITRFSPARHIDIKYAQLLSEAQNKGVEVLAYKAELSAQKMELNEPVPITL
What is the function of this protein?
Binds to DNA non-specifically.  Could be a regulatory factor involved in maltose metabolism.
What are the official names of this protein?
Sugar fermentation stimulation protein A.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: RNH2_SYNAS
Sequence: MIGMDHFEREAYEDGYRVIAGVDEAGRGPLAGPVVAAAVILPHGYSHPEITDSKKLSAGKREKLYEVIKRDALAIGVGVVESPVIDQVNILRATLRAMAEAVDDLSIRPDFLLVDGLHRIFLNISQKTIVKGDTLSVSIASASIIAKVSRDRIMEIYHRQFPQYNFLKNKGYGTREHREAIQNFGFCKIHRRSFKVKSTKPQSLQTVNLFDF
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPL2_ARATH
Sequence: MNRLGHKSVVYHGDLRLGELDVNHVSSSHEFRFPNDEIRIHHLSPAGERCPPLAILQTIASFAVRCKLESSAPVKSQELMHLHAVCFHELKTAVVMLGDEEIHLVAMPSKEKKFPCFWCFSVPSGLYDSCLRMLNTRCLSIVFDLDETLIVANTMKSFEDRIEALKSWISREMDPVRINGMSAELKRYMDDRMLLKQYIDNDYAFDNGVLLKAQPEEVRPTSDGQEKVCRPVIRLPEKNTVLTRIKPEIRDTSVLVKLRPAWEELRSYLTAKTRKRFEVYVCTMAERDYALEMWRLLDPEAHLISLKELRDRIVCVKPDAKKSLLSVFNGGICHPKMAMVIDDRMKVWEDKDQPRVHVVSAYLPYYAPQAETALVVPHLCVARNVACNVRGYFFKEFDESLMSSISLVYYEDDVENLPPSPDVSNYVVIEDPGFASNGNINAPPINEGMCGGEVERRLNQAAAADHSTLPATSNAEQKPETPKPQIAVIPNNASTATAAALLPSHKPSLLGAPRRDGFTFSDGGRPLMMRPGVDIRNQNFNQPPILAKIPMQPPSSSMHSPGGWLVDDENRPSFPGRPSGLYPSQFPHGTPGSAPVGPFAHPSHLRSEEVAMDDDLKRQNPSRQTTEGGISQNHLVSNGREHHTDGGKSNGGQSHLFVSALQEIGRRCGSKVEFRTVISTNKELQFSVEVLFTGEKIGIGMAKTKKDAHQQAAENALRSLAEKYVAHVAPLARETEKGPENDNGFLWESSEDVSNKGLEEEAPKENISEL
What is the function of this protein?
Processively dephosphorylates 'Ser-5' but not 'Ser-2' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1).  This promotes the activity of RNA polymerase II.  Together with CPL1, required for male gametes fertility.  Multifunctional regulator that modulates plant growth, stress, and phytohormones responses.  Positive transcription regulator of genes involved in high salinity resistance and auxin mediated signaling pathway.
What are the official names of this protein?
RNA polymerase II C-terminal domain phosphatase-like 2, FCP-like 2, Carboxyl-terminal phosphatase-like 2, AtCPL2, CTD phosphatase-like 2.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: Y752_METJA
Sequence: MMEVIKAIEFKYYSDVVELIYDFKEMVNFCIDKAMELGITSYAKLRKAIYNEWKEKWYPKYHTHYCHSACRVATSI
What are the official names of this protein?
Uncharacterized protein MJ0752.
What is the protein family that this protein belongs to?
To M.jannaschii MJ0857 N-terminal region.
Protein: RL35_SALAI
Sequence: MPKMKSHTGMGKRVRVTGKGKIVKQQAGLRHNLEKKPSTRTRRLTGLVEVAKPDVKRIKKLLGR
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: NAC60_ARATH
Sequence: MAAAPPIEPAVTTTFPGFKFSPTDIELISYYLKRKMDGLERSVEIIPEVEIYNFEPWDLPDKSIVKSDSEWFFFCARGKKYPHGSQNRRATKIGYWKATGKERNVKSGSEVIGTKRTLVFHIGRAPKGGRTEWLMHEYCMIGVSLDALVICRLRRNTEFQGSTIQKPPQPSLPLDKHVNLRNEAISESIYGWETMVDFYLSSESGQELLSEIAESSQSSQNPQVPSEEDFYADILRDEIVKLDDPAVSGNTLINVPRLQTESNTTRVLPLPDMVDKQMQSLLQKLPLQNDTGEENNISMSNCFIGIYSIKSINRARWDVVVWLLVMIAVLVFYLV
What is the function of this protein?
Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP) (By similarity).  Transcription factor involved in modulation of abscisic acid (ABA) signaling.  Attenuates ABA sensitivity and glucose-induced ABA accumulation.  Reduces the expression of ABI4 gene.
What are the official names of this protein?
NAC domain-containing protein 60, ANAC060, Protein NTM1-like 5.
What are the subcellular locations of this protein?
Membrane; Single- pass membrane protein. Nucleus. Note=Localized primarily in plasma membrane or endoplasmic reticulum membrane as dormant form and, upon specific stress or signal, is processed into a transcriptionally active and nuclear form after a proteolytic cleavage through regulated intramembrane proteolysis (RIP).
Protein: Y1651_CORGL
Sequence: MKLFSRTSLVALGTAAAITLSGVTAPAFADEDSNAAVSALKTAEDNTPEAPGASTPLKLEQPGTITGVPGKAITPVTVKVVAGEAESFTSDNLPSGLLIDNTGKITGTPKKEFTGSAKIIAKNEAGVEAEVYVNFDFNEEPSSEEPSSGSSDTDNIENWIKIITAVIGALTTILTFSTKLDSFLK
What are the official names of this protein?
Uncharacterized protein Cgl1651/cg1859.
What are the subcellular locations of this protein?
Secreted.
Protein: PHK_GLOVI
Sequence: MVVAKIEKTGTLSTEQLQKMHAYWRAANYLSVGQIYLMDNPLLREPLKLEHVKPRLLGHWGTTPGLNFIYVHLNRVIQDEDLDMIYIAGPGHGGPGLVANTYLEGTYSEYYPNISEDAEGMKRLFKQFSFPGGIPSHVAPETPGSIHEGGELGYAVSHAYGAVFDNPDLIVACVVGDGEAETGPLATSWHSNKFLNPVRDGAVLPILHLNGYKIANPTVLARISHEELEKLFEGYGYKPYFVEGSEYEPTHQLMAATLDTCIAEIKAIQHEARTGGATARPRWPMIVLRTPKGWTGPKEVDGKKTEDFWRSHQVPFSEMAGKPEHVQLLETWMRSYQPEELFDENGTFLGELKALAPKGHRRMGDNPHANGGILLKDLKMPDFRSYAVDVAKPGTTFAEATKVMGIFLRDVMKANLDQRNFRIVGPDETASNRWGPLFEITNRTWMDAIHPYDDHLSQDGRVMEILSEHTCQGWLEGYLLTGRHGFFSCYEAFIHLVDSMFNQHAKWLKTTRHIPWRRPIASLNYLLTSHVWRQDHNGFSHQDPGFIDHVVNKRAEVIRVYLPPDANTLLSVTDHCLRSRHYVNVVVAGKQPALQYLDMDAAIKHCTKGIGIWDWASNDQGVEPDVVMACCGDIPTLETLAAVDILRQNFPDLKIRVINVVNLMKLQPESEHPHGLSDKDFDSIFTPDKPVVFAFHGYPWLIHRLTYRRNNHNNIHVRGYKEEGTTTTPFDMVVMNDLDRFNLADDVIDRVPRLRYTAAHVKQMLHDKLIEHKQYIHEHGDDMPEIRDWCWPY
What are the official names of this protein?
Probable phosphoketolase.
What is the protein family that this protein belongs to?
Belongs to the XFP family.
Protein: UVRB_CARHZ
Sequence: MERFLLKANYTPKGDQPKAIKELTEGIEKGLKMQTLLGVTGSGKTFTMANVIANVNKPTLVIAPNKTLAAQLCAEFREFFPENAVEYFVSYYDYYQPEAYLPATDTYIEKDSAINDEIDKLRHSATAALFERRDVIIVASVSCIYGLGDPQEYRELLLSVRKGQIYEREAILRKLVDIQYERNEYDLTRGKFRVRGDVIEVFPASYTDRAVRIELFGDEVDRILEFDTLTGEIIGELKHVAIFPASHFATSKEKLERAIKSIEEELEERLRYFEERGKLLEAQRLKQRTLYDIEMLREVGYTKGIENYSRHLTGRKPGEPPYTLIDYFPKDFLMIIDESHITIPQIRGMYEGDRSRKEALVEYGFRLPSAFDNRPLKFHEFEARINQVVFVSATPGPYELKHSQKIVEQIIRPTGLVDPEVEVRPTRGQVDDLYGEIKERVARNERVLVTTLTKKMAEDLTEYFREMGVKVRYLHSDIDTLERVEILRDLRLGVFDVLVGINLLREGLDLPEVSLVAILDADKEGYLRSERSLIQTIGRAARNVNGKVIMYADTVTASMQKAIDETNRRRKLQMEYNRKHGITPQTVQKAVRDVIEATRAVTAELPEVKRDFIQKMSAKEFKQYVEKLTREMKEAAKALEFEKAAMLRDLIIELRAQKAVKK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_SYNY3
Sequence: MAAANSWWEIRILCHPSLEETAFWRLEKFGCLGTSTEKKAHSLLVRGYLPQEKAEILDLAALALWCEQDALLFQVPKPRFHWQLIDEEDWSISWKEHWQPTPVGDRFIIYPAWIDPPENSDRLILRLDPGVAFGTGTHATTQLCLESLEMRVEPDKHQVLADLGCGSGILGIGAVLLGAAKVYGVDNDPLTVESARHNRHLNQIHPDNLVINEGSVPELEQLIAEPVDGIICNILAEVIVDLLPQFTPLVKPHGWAILSGIMVEQSQAIADALEQNGWTVVAIWKRQEWCCFQARREEGD
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGK_VIBVU
Sequence: MYYGFDVGGTKIEFGAFNEKLERVATERVPTPTDDYPLLLETIAGLVAKYDQEFACEGKIGLGLPGMEDADDATVLTVNVPAAKGKPLRADLEAKIGRSVKIENDANCFALSEAWDEELQDAPSVMGLILGTGFGGGLIYEGKVFSGRNNVAGELGHMRLPLDAWFHLGDNAPLLGCGCGKKGCLDSYLSGRGFELLYAHYYGEEKKAIDIIKANAAGDEKAAEHVERFMELLAICFGNIFTANDPHVVALGGGLSNFELIYEEMPKRVPKYLLSVAKCPKIIKAKHGDSGGVRGAAFLNIKG
What is the function of this protein?
Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
What are the official names of this protein?
N-acetyl-D-glucosamine kinase, GlcNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NagK subfamily.
Protein: CY1_BLAVI
Sequence: MTIKLRFVASLALVFGLAAASVPAQASGGDTPHLQSWSFAGPFGQYDKAQLRRGFQVFQNVCVSCHTLENGGFRNLPSRAAPNWPLDEVRQLAASWPVQVKDINDKGDPMQRAPKLPDRIPSQYANEAAARIIHNGAVPPDLSVIAKARTFQRGFPWWVTDIFTQYNENGVDYIVALLNGYEDPPERFKVPDGSFYNKYFPGHIIGMTPPIADGLVTYGDGTPETQLQYSKDVAAFLMWAAEPTLDVRKRIGWWVLGFLVIFTGLLVATKIVVWRPVKKGLA
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.  c1 functions as an electron donor to cytochrome c.
What are the official names of this protein?
Cytochrome c1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: FIBA_AMMLE
Sequence: ADDSDPVGGEFLAEGGGVR
What is the function of this protein?
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.  Fibrin has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen alpha chain.
What are the subcellular locations of this protein?
Secreted.
Protein: MUTA_PIG
Sequence: MLRAKTRLFLLSPHRLKQLKKSSGSRLVWQRLLHQQQPLHPEWAALAKKQLKGKNPEELIWHTPEGISIKPLYSSRDTKDFPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDIIKAGQQGLSVAFDLATHRGYDSDNPRVHGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLATFIVSGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFQYTAKHMPKFNSISISGYHMQEAGADAILELAYTIADGLEYCRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFRRKNSKSLLLRAHCQTSGWSLTEQDPYNNIIRTTVEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMESLTNDVYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEESVEVLAIDNTSVRNKQIEKLKKVNPAGIKLWLERCLTALTACAASGDGNILALAVEATRARCTVGEITDAMKKVFGEHKANDRMVSGAYRQEFGESKEISFAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLAAGHKTLVPELIKELSTLGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAAVQVLNDIEKCLEKKQQSM
What is the function of this protein?
Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle.
What are the official names of this protein?
Methylmalonyl-CoA mutase, mitochondrial, MCM, Methylmalonyl-CoA isomerase.
What is the protein family that this protein belongs to?
Belongs to the methylmalonyl-CoA mutase family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Mitochondrion. Cytoplasm.
Protein: PDXS_STAA9
Sequence: MSKIIGSDRVKRGMAEMQKGGVIMDVVNAEQARIAEEAGAVAVMALERVPSDIRAAGGVARMANPKIVEEVMNAVSIPVMAKARIGHITEARVLEAMGVDYIDESEVLTPADEEYHLRKDQFTVPFVCGCRNLGEAARRIGEGAAMLRTKGEPGTGNIVEAVRHMRQVNSEVSRLTVMNDDEIMTFAKDIGAPYEILKQIKDNGRLPVVNFAAGGVATPQDAALMMELGADGVFVGSGIFKSEDPEKFAKAIVQATTHYQDYELIGRLASELGTAMKGLDINQLSLEERMQERGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: SYC_SHEON
Sequence: MLKIYNSITRQKQEFKPINPGKVGMYVCGVTVYDLCHIGHGRTFVSFDMIVRYLRYAGYEVNFQRNITDIDDKIIKRANENQEDCNTLTDRLIGEMHKDFDALNMKRPDFEPRATLHIAEIIDMVERLLARGHAYVAADGDVLFSVASFPEYGRLSGQNLEQLQAGARVEVDDNKQNPMDFVLWKMSKPGEPTWESPWGPGRPGWHIECSAMNSKHLGLHFDIHGGGSDLQFPHHENEIAQSCCAHDTPYVNYWMHTGMVMIDREKMSKSLGNFFTIRDVLSHYDAETVRYFLLSGHYRSQINYSEENLKQARAALERLYTAIKDVDLTVAAAPAEEFVAKFKAAMDDDFNTPEAYSVLFDMVREINRLKLTDMAEASALAVSMKQLADVLGLLHQSPDAFFKGEGSDDEVAEIEALIVERNRARTEKDWPAADVARNRLNELGVVLEDGPSGTTWRKK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPPY_SALTY
Sequence: MVQCVRHSVLPRLKKDAGLPFFFPLKTNTKPLN
What are the official names of this protein?
pyr operon leader peptide, pyrBI operon attenuator.
Protein: ECHB_MACFA
Sequence: MTTILTCPFKKLPTTSKWALRFAIRPLSCSSQLRAAPAVQTKTKKTLAKPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDIPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRLNFLAPELPAVAEFSTSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSDVVPFRVPGKDTVTKDNGIRPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVEAYPK
What is the function of this protein?
Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway.  The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA.  Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long-chain fatty acids.  Mitochondrial trifunctional enzyme is a heterotetrameric complex composed of two proteins, the trifunctional enzyme subunit alpha/HADHA carries the 2,3-enoyl-CoA hydratase and the 3-hydroxyacyl-CoA dehydrogenase activities, while the trifunctional enzyme subunit beta/HADHB described here bears the 3-ketoacyl-CoA thiolase activity.
What are the official names of this protein?
Trifunctional enzyme subunit beta, mitochondrial, TP-beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane. Mitochondrion outer membrane. Endoplasmic reticulum. Note=Protein stability and association with membranes require HADHA.
Protein: RS4_IDILO
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDSKCKIETAPGQHGARRGRLSDYGVQLREKQKVRRMYGVLEKQFRNYYKEAARLKGNTGENLLQLLEQRLDNVVYRMGFASTRAEARQLVSHKAVVVNGQVVNIPSFKVRPEDVVSVREKAKKQARIGAALELAEQREKPVWIEVDNNKLEGAFKRLPERSDLSAEINEQLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: CYB_CEPNE
Sequence: MAPSLKKIVLWSFLALPSPVNISIWWNIGSLLGLLLAMQIMTGIFLSLHYTPMMVSTFSSMVHIMRDVPGGWLVRASHANGASMFFMLMYAHIGRGVYYQSYILQPRTWLVGGNDFLLSMATAFLGYVLPWGQMSYWGATVITNLLSAVPYLGDSLVTWVWGCFSVNQATLNRFYSFHFLLPFVILVFVLVHLLLLHDKGSSNPLGNMSHVSKVSFHPYFTWKILWVFVLLCFLLYVLLCYITLMYLRTPKTFIEANPMVTPTHIQPEWYFLFAYAILRAIPSKIGGVVALAMSVLYLYTFPLALYSSAAATAYNFIGQLLFWGYVSLFFLLTWLGACPVEEPYISLALPLTVMFFVVPGLYMISSSYIIRSFQFLLSLK
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL1_HALH5
Sequence: MAKRGKKYLEAVKLIDRDQAYQVEEALELVKKASVAKFDETVEVAVRLGVDPKKADQQIRGAVVLPNGTGKTQRVLVFAKGEKAKEAEAAGADYVGDEDCINKISQGWFDFDVIVATPDMMAQVGKLGRVLGPKGLMPNPKTGTVTFEVEKAVNDIKAGKVEYRVDKAGNIHVPIGKVSFDTAKLAENFETIIDTLVKAKPAAAKGTYLKNIAVSSTMGPGVKVSTASFGK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: P5F11_XENTR
Sequence: MYSQQPFPPFAFNAGLIQDPANCHFGGYTGLGHPQPFSFAFSTLKSENGDSGVQGMGDCSAPVMPWNSMASFDHHGQVETNQQGNPIRAPSPTPTLSDSRIKVKEEVAHETDSGEESPEPKYPSPPNPSLYYPNTWTGSPFWQVNPTAGNNSNSTNPMPSQTLVKNGSLPGNTTYPTPANQSPNTPVDCVVSSMESSRCSSANSSNGAINERATTIPNGGMVDGGQSSDNEEEVPSESEMEQFAKDLKHKRVSMGYTQADVGYALGVLYGKMFSQTTICRFESLQLSFKNMCQLKPFLERWLVEAENNDNLQELINREQVIAQTRKRKRRTNIENIVKGTLESYFMKCSKPGAQEMVQIAKELNMDKDVVRVWFCNRRQKGKRQGMPTVDENDGEGYDVGQTMASPPVGHYSLPQVVTSQGYMAAPLGSTPPLYASAFHKNELFPQPLPHAMPMGGHIG
What is the function of this protein?
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3').  Activates transcription when directly bound to the octamer DNA sequence, but can form repression complexes with other proteins at the promoter site to inhibit transcription.  Binds to the promoter of the vent2-B gene to activate transcription when in the presence of other BMP signaling factors also bound to the promoter.  Inhibits the competence of ectodermal cells to respond to BMP during embryogenesis thereby inhibiting epidermal differentiation and promoting neural induction.  Antagonizes the activity of nodal/activin signaling by forming a transcriptional repression complex on the gsc and mix2 gene promoters to inhibit their transcription, and thus maintain the undifferentiated state of embryonic cells to prevent them from differentiating prematurely.  Acts maternally to inhibit vegt and beta-catenin-activated gene transcription by forming a transcriptional repression complex on the nodal/nr1 and siamois promoters to inhibit their transcription (By similarity).
What are the official names of this protein?
POU domain, class 5, transcription factor 1.1, POU class V protein oct-25.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-5 subfamily.
What are the subcellular locations of this protein?
Nucleus.