PharMolix/UniProtQA huggingface dataset:
Protein: PYRG_LACDA
Sequence: MTKYIFVTGGVVSSLGKGITASSIGRLLKNRGLKVTMQKFDPYINIDPGTMNPYQHGEVFVTDDGTEADLDLGHYERLVDVRTSKYSNVTTGKIYQEVLQRERRGDYHGGTVQVIPHVTNMIKEKVMRAAQMTDTDVVISEIGGTVGDMESTPFMEAIRQMRREVGSENVMYVHVTFVPYLRAAKELKSKPTQQSVSMLRSIGIQPNMLVLRSEMPVPQEMKDKISTFTDVPVDYIVESLDAPSLFDVPLSYQEQGVDQKVVDFLHIDSPKPVADMDEWRRMDERAKNLKYKTKITLVGKYVELEDAYISVTDALHHAGYLYNSKIEVEKIQAEDITEDNVAELLKDTQGLIVPGGFGTRGLDGMITSIKYAREHDIPFLGICLGMQMASVEFARNVLHLEDANSAEAEPNCKNNIIDLMADQRDQEKIGGTLRLGLYPAMLKAGTKTRECYDGQEVIQERHRHRYEFNNKYREDFEKAGMTFSGISPDNHLVEIVEITDKKFFVAAQYHPEFLSRPNRPEGLFKGFIGAASGLQVDKF
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: SSRP_RHOJR
Sequence: MKEKGRKVIATNRKARHNYTILDVYEAGIALVGTEVKSLREGKASLVDAFATVDDGEVWLRSLHIPEYTQGTWTNHAPRRTRKLLLHKQEIEHLVGKTREGNQTLVPLSMYFSDGKVKVELALAKGKQDYDKRQDLARRTAEREVTRELGRRVKGMR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: APT_STAAW
Sequence: MDLKQYVSEVQDWPKPGVSFKDITTIMDNGEAYGYATDKIVEYAKDRDVDIVVGPEARGFIIGCPVAYSMGIGFAPVRKEGKLPREVIRYEYDLEYGTNVLTMHKDAIKPGQRVLITDDLLATGGTIEAAIKLVEKLGGIVVGIAFIIELKYLNGIEKIKDYDVMSLISYDE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIM12_BOVIN
Sequence: MWPVLWTVVRTYAPYVTFPVAFVVGAVGYHLEWFIRGKEPQPVEEEKSISERREDRKLDELLGKDHTQVVSLKDKLEFAPKAVLNRNRPEKN
What are the official names of this protein?
Small integral membrane protein 12.
What is the protein family that this protein belongs to?
Belongs to the SMIM12 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DTL_XENTR
Sequence: MLFRSVVNKPRLGCRQRGVPFTHPLQSLLQCYQCAKHDEHTSYGELGAAVPPFGCAFSTVPDMSHVLAVANEEGIVRLYDTECRDVQRLVVKEFMAHTNAVFDIAWVPGEHKLVTASGDQTAKLWDVKAGDLIGECKGHQCSLKSVAFSKFEKAVFSTGGRDGNIMVWDTRCNKKDGFYRQVNQITGAHNALDKQTPSKVKKRKPYVRGLAPSVDSQQSVTVVIFQDEHTIISAGAVDGIVKVWDLRKNYSAYRQDPVPAKLFPYPGNSTRKLGYSNLVLDPTGTNLFASCTDDNVYMFNATGLKTEPVSVFGGHQNSTFYIKTSVSPDGQFLLSGSSDHSAYIWQVSDPKVPPVTLTGHCQEVTSVAWCQSDFTKIATCSDDNTVRVWRLKRSSEDSAQSDKTETVGWACQKKCVPPSMAANLCTPGKPSMIPSSSLMSSPTPATCAPSYTGDLPMPSSTPVSALLPIPKLQTPQRLNGEGLGASPKQTSSSKISIKDWITRTPKSSTRADTKTPSPRKAFTPVEQYPSVSSTRVQMPYEKRAKRRLETSSEDVEHVCLDHCNCVMELEPGLKKAKLDLCSFSEKERDGSDDKCLRLSDLSRGFDQEFSPGPSTSFLINGTVNPPLSPLSELKSDLRDKENSSPEKNWLSALGHKFKSDKSSPQNKAASSPSSRNSTSKKHPTRNAPNSPVSVPTTPGSMRKICTYFFKKSE
What is the function of this protein?
Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis.  The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1, CDKN1A/p21(CIP1), KMT5A and SDE2.  CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle regulation of DNA replication.  CDKN1A/p21(CIP1) degradation during S phase or following UV irradiation is essential to control replication licensing.  KMT5A degradation is also important for a proper regulation of mechanisms such as TGF-beta signaling, cell cycle progression, DNA repair and cell migration.  Most substrates require their interaction with PCNA for their polyubiquitination: substrates interact with PCNA via their PIP-box, and those containing the 'K+4' motif in the PIP box, recruit the DCX(DTL) complex, leading to their degradation.  In undamaged proliferating cells, the DCX(DTL) complex also promotes the 'Lys-164' monoubiquitination of PCNA, thereby being involved in PCNA-dependent translesion DNA synthesis (PubMed:16949367).  May play a role in the regulation of the circadian clock (By similarity).
What are the official names of this protein?
Denticleless protein homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat cdt2 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome.
Protein: HSLV_BRUSU
Sequence: MIEHNPTTIYGTTIVTVRKDGKVVIAGDGQVSLGNTVMKGNARKVRRIGKGNVIAGFAGATADAFTLLERLEAKLEQYPDQLMRASVELAKDWRTDRYLRKLEAMMLVADSKVTLALTGTGDVLEPEQGVMAIGSGGNYALAAARALIETDKSAEEIARKAMNIAADICIYTNHNIIVESLDAQ
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAP4_ARATH
Sequence: MDVPRPAFKCFDDDGRLKRSGTVWTASAHIITAVIGSGVLSLAWAIGQLGWIAGPTVMLLFSFVTYYSSTLLSDCYRTGDPVSGKRNYTYMDAVRSILGGFRFKICGLIQYLNLFGITVGYTIAASISMMAIKRSNCFHESGGKNPCHMSSNPYMIMFGVTEILLSQIKDFDQIWWLSIVAAIMSFTYSAIGLALGIIQVAANGVVKGSLTGISIGAVTQTQKIWRTFQALGDIAFAYSYSVVLIEIQDTVRSPPAESKTMKIATRISIAVTTTFYMLCGCMGYAAFGDKAPGNLLTGFGFYNPFWLLDVANAAIVIHLVGAYQVFAQPIFAFIEKQAAARFPDSDLVTKEYEIRIPGFRSPYKVNVFRAVYRSGFVVLTTVISMLMPFFNDVVGILGALGFWPLTVYFPVEMYIRQRKVERWSMKWVCLQMLSCGCLMITLVAGVGSIAGVMLDLKVYKPFKTTY
What is the function of this protein?
Amino acid-proton symporter.  Stereospecific transporter with a broad specificity for neutral amino acids, favoring small amino acids such as alanine, asparagine and glutamine.  Accepts also large aromatic residues such as in phenlalanine or tyrosine.
What are the official names of this protein?
Amino acid permease 4, Amino acid transporter AAP4.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. Amino acid/auxin permease (AAAP) (TC 2.A.18.2) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ALBF_BACSU
Sequence: MEKKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFGSRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMFTSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLISMLSPSSPAAVFPAGRIEDIEALDISDLQKAYKAAYQAHRMTLFLIGGSENTETLLPPHLQLEKRPDYHAERKIIPACPPVLSQKMMLGDEERMEDTWTGLQIGALPGQNDLLSIKLYWDIAARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYVTQKKEQVAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQVFLSLIDAMASSNKAIIHVSQKEAIRQ
What is the function of this protein?
Required for production of the bacteriocin subtilosin.  Could catalyze some step in the processing of presubtilosin.
What are the official names of this protein?
Putative zinc protease AlbF, Antilisterial bacteriocin subtilosin biosynthesis protein AlbF.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family.
Protein: NUSB_LEPBL
Sequence: MSARRTSREIAVMALYQLELTGPPLKEVLKFKWYDKKTEPEERDFAVSIVNGVVKNQEQIDTLIKKYSKNWDFSRISIVNKAILRLSVFALLYSWEVPKNVTIDEAVELTKEFESEESARFVNGILDAILKNETKSDG
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: MURI_ERWT9
Sequence: MPMKPLDGETTSTEKLSPVLRPTVLIFDSGVGGLSVYNEIRTLLPDLHYLYAFDNVAFPYGEKSEAFIVERVLDIVTAVTGLYPLALVVIACNSASTVTLPALRARFAFPVVGVVPAIKPAARLTRNGIVGLLATRGTVKRPYTHELVARFAGECKTEMLGSGELVDIAEAKLHGQPVAIEEVRRILQPWLRMAEPPDTVVLGCTHFPLISEELQQVLPQGTRLIDSGAAIARRTVWLLENESPEVLSADDNMALCLEITEQTVQLIPVLQRYGFKTLKKLAL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: NUOI_RICFE
Sequence: MINYLKSFFLYEIVRGMALTLKYFFKPKVTINYPYEKSPVSPRFKGEHALRRYENGEERCIACKLCEAICPAQAIVIEADERDDGSRRTTRYDIDMTKCIYCGLCQEACPVDAIVEGPNFEFASLTHTALIYDKERLLQNGDRWEQALASKLHKDYEYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: COAA_STRGC
Sequence: MTNEFLHFDRISRERWQQLHRKTTPPLTEEELNSIKSFNDEISLQDVMDIYLPLTNLIQIYKRAKEDLAFSKGIFLQKTLKKQPFIIGVSGSVAVGKSTTSRLLQILLSRTFENAKVELVTTDGFLYPNSVLQEHDLLNRKGFPESYNMELLLNFLDHLKNGQNYQVPVYSHEIYDIVPDQTQTIQVADFVIVEGINVFQNPQNERLYITDFFDFSIYVDAEVENIEKWYLDRFGKLLDLARRDSKNYYHRFTKEPVEDIMKMARNIWKSINLVNLKDYIEPTRNRAELILHKAHNHEIDEIYLKK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRISA_PODAS
Sequence: MPIINGQKMACGPCIRGHRSTKCNHYNERVMVPVRKPGRPLSTCPCPPGKPCVCGGVRVAIPKKQKCHCPAGTVDSATSSEFDPSPVDTPISPASRTSSNRVTKSGSGSKSASRRQSLALANLERMDPNSINLIPSPNGNGMIGITAMVSPRDATFGHPMGMVPMGPRESFVPAPPPDFGGPMGYNMPPSMPPHMPPPHYPPHIQIPQHIKTENGGFVPMLNGTFVSPVPIPAFVDGPHPQGMQAFNGPPPPPPSNPVLEPSAMSKPKGGSGGGGCCGGGKKAPQIQAPPPVPAPLPTPPQQQMPNIMPPPQPQNAPSGGGGSCCSSKSSQPPPMPQMSPNAMQAPPQPGFGQGFMPQYQTPIDIKMENMHHHQPFQFPGQTVFTYPAEYGSWQMPINPAIWQQVVSRPPTQQQHETPISATAPNGNNGTVGGNSHECGCGEGCQCVGCLAHPFNSQMLQYVQNAYSPNSSHGNSGSADSSANASPSANPLNLASPVEIPSGPELPPSHQTQPQPPPRPNANESDGSSNAPTPPNEGSPALSNEEELTALDYYFVHLPISALCGGALDMCPCDESCECVGCLVHNTAGFPQGDGGFS
What is the function of this protein?
Copper-sensing transcription factor that regulates copper uptake by transactivation of Ctr3, a high affinity copper permease.  Binds to the palindromic UAS sequence 5'-TGTTGCTCANNNNAGAGCAACT-3'.  Also transactivates Sod2, a mitochondrial manganese superoxide dismutase through the palindromic UAS sequence 5'-GTTTGCTCA-3' with 352 bp separating the two inverted repeats.  Loss of function indirectly leads to rearrangement of mitochondrial DNA associated with senescence in wild-type strains.
What are the official names of this protein?
Protein GRISEA, MAC1 homolog.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYR_CHLL2
Sequence: MQEFLLPVIKSALQSAAIETDKPVQIEKPTDKKNGDFSTNIALLLSKECRRNPRELAAELIGQMIFPDGTVERIEIAGPGFINFYLTPLFIMQSVEHILLEGKGYGSSCAGKGKTAIVEYVSANPTGPLTIGRGRGGVLGDCIANLLATQGYGLTREYYFNDAGRQMQILGESVRYRYMERCGRDIVFPESHYQGEYIREIAEILFLEHESSLIDSDNLSIFKDTAEAIIFSSIKKTLARIDIRHDSFFNEHTLYIAEGNGKSANDRVLELLESKGFIDRYDGATWFLTTKLGQEKDKVLVKSSGEPSYRLPDIAYHLDKYRRKFDLIVNVFGADHIDEYPDVLEALRILGHDTSKMRVAINQFVTTTVDGETVKMSTRKGNADLLDELIDDVGADATRLFFIMRSKDSHLNFDIELAKKQSKDNPVFYLQYAHARICSLLRIAAEEAGFKPDGSGAHLLQKLTLEPEIQLGFTLLDYPEVIRTAIRLLEPQKMVEYLHSVAEQYHKFYQECPILKADPDIRTARLFLSLATRQVLRNGFTILGISAPESM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_CELJU
Sequence: MGKIIGIDLGTTNSCVSILEGGAPKVIENAEGDRTTPSIIAFTNDGEILVGQSAKRQAVTNPHNTLFAVKRLIGRKFKDDVVQKDISMVPYKIVAADNGDAWVEVKGEKKAPPQISAEVLKKMKKTAEDYLGEKVTEAVITVPAYFNDSQRQATKDAGKIAGLDVKRIINEPTAAALAYGLDKGKGDHTIAVYDLGGGTFDISIIEIADVDGEHQFEVLSTNGDTFLGGEDFDMRLIEFLADSFKKDTGIDLHNDPLALQRLKEAAEKAKIELSSSQQTEVNLPYITADATGPKHLVVKLTRAKLESLVEDLVNKSLEPVKQAIKDSGKSISDIDDVILVGGQTRMPLVQKAVADYFGKEPRKDVNPDEAVAIGAAIQGAVLAGDVKDVLLLDVTPLTLGIETMGGVATPLIEKNTTIPTKKSQVFSTADDNQTAVTIHVVQGERKQASQNKSLGRFDLADIPPAPRGMPQIEVTFDIDANGILNVSAKDKATGKEQSIVIKASSGLSDDEIQKMVKDAEANAEADRKFAELVGARNTLEGLIHATQKTVKEAGDKATADEKAAIDAAVKEAEEAVKGDDLARIEAATTKLTEASSSLAQKLYAEQQAAGAGAQQADGTGKAADDGVVDAEFEEVKEDNK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: ADAT1_DICDI
Sequence: MSWKLDKQFSDKICNFSHDFFNKKLIKKGKPISGEWTVLATLVLVVENTSSYEIKQVLSLGTGNRCLGKSSLSNQGDVLNDSHAEIICKRSFQKFCYNEILNLLQSKYYNSILFNIEYHDSNNNNKDNDNNGSLPTISIKKGHSLHFYVNQTPCGDCSIFPFKKETQPENFIEKEKLEKDGKDKIENHEKKEQKDIIKQVDKDKDEENYEDEESKRKLKKVKDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNNNNQYDDIQRTGAKTVFGEPEDKKLIGVDYHQIGVLRVKPGRGDPTVSMSCSDKIARWNVLGIQGSLLSHFIKEQIFLSSITIGDLFNHSSIYRGLIGRLLPNPTTTTTETSSSSSSSSSSSNTIPNFKLNSDLEIFSTNIQFQFSKLLLESDQQNNNKSTSSGLAISFCYPNQHEVTIAINGKKMGTNQKNFNAISQRSSICKFNLFKLFHQLVLIIKNKNSNEENEKNNQIVLIDSLFNYYECKHLSKKYYQEYEKLKEFKFKNWLTNSSDLENFVLDN
What is the function of this protein?
Specifically deaminates adenosine-37 to inosine in tRNA-Ala.
What are the official names of this protein?
tRNA-specific adenosine deaminase 1, tRNA-specific adenosine-37 deaminase.
What is the protein family that this protein belongs to?
Belongs to the ADAT1 family.
Protein: NIBA2_MOUSE
Sequence: MGDVLSTHLDDARRQHIAEKTEKILTEFLRFYEDQYGVSLFNSMRHEIEGTGPPQAQLLWRKVPLDERIIFSGNLFQYQEDNKKWRNRFSLVPHNYGLVLYENKVAYERQIPPRAVINSAGYKVLTSVDQYLELVGNSLPGTTSKSGSTPILKCPTQFPLILWHPYARHYYFCMMTEAEQDKWQAVLQDCVRHCNNGIPENSKVEGPAFTDAIRMYRQSKEQYGTWEMLCGNEVQILSNLVMEELGPALKAELGPRLKGKPQERQRQWIQISDAVYRLVFEQAKVHFEDVLCKLQRARPAMEAVIRTDMDQIITSKEHLASKIRAFILPKAEVCVRNHVQPYIPSILEALMVPTSQGFTEVRDVFFKEVTDMNLNVINEGGIDKLGEYMEKLSQLAYHPLKMQSCYEKMEPLRLDGLQQRFDVSSTSVFKQRAQIHMREQMDNAVYTFETLLHQELGKGPTKEELCKSIQRILERVLKKYDYDSSSVRKRFFREALLQITIPFLLKKLAPTCKSELPRFQELIFEDFARFILVENTYEEVVLQTVMKDILQAVKEAAVQRKHNLYRDSMVLHNSDPNLHLLAEGTPIDWGEQYGDSGDSGGGDSGGSPCPSEAATLTEKRRRAKQVMSVVQDEESGLPFEAGVEPPSPASPDSVTELRGLLAQDLQAESSPPASPLLNGAPVQESSQPVAVPEASPPASPLRHLPPGKAVDLEPPKPSDQETGEQVSSPGSRPPIHTTTEDSAGVQTEF
What is the function of this protein?
May play a role in apoptosis suppression.
What are the official names of this protein?
Protein Niban 2, Meg-3, Niban-like protein 1, Protein FAM129B.
What is the protein family that this protein belongs to?
Belongs to the Niban family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell junction, adherens junction. Membrane; Lipid-anchor. Note=In exponentially growing cells, exclusively cytoplasmic. Cell membrane localization is observed when cells reach confluency and during telophase (By similarity). Phosphorylation may play a role in relocalization to the membrane (By similarity).
Protein: NOC_BACAN
Sequence: MKNTFSRLFGFGDKESEFELQDESHEEIDKKVYEEIQEIPIVNITPNRYQPRTVFDDARIEELALTIRTHGLIQPIVVRQYEDDKYEIIAGERRFRAATKLGWEKVPAIIKNLNDTETASVALIENLQREELTAIEEAVAYQKLIELHNLTQEALAQRLGKGQSTIANKLRLLKLPEEIKSALLEKSITERHARALIPLKNEELQLKVLQEIVEKQLNVKQTEERITKLLEEAKPKRKAKQKAVSRDTRIAMNTIRQSLQMVADSGLNVNSEEEEFDEYYQITIQIPKKK
What is the function of this protein?
Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle.  It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage.
What are the official names of this protein?
Nucleoid occlusion protein, Noc.
What is the protein family that this protein belongs to?
Belongs to the ParB family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: TOP1_BACAN
Sequence: MKSPRFRHSQKYIGSKPYYGYYENDHYIVSWCRGHLLELKNPEEMDPKYKLFQLEHLPLIFQPSYKVIQENAEQLQILVKLLQRPDVDHAVNICDADREGELIYREVYEYAGVNKKQSRVYKSSFEAAELEAALNRLESASKYDGLAYSAKARQYLDYLLGMNITRGCTTKLAQNKFLLSSGRVQMCLLHEIRQRELAIENYREQSYYHLQLITDLGLKPVMKTEDQVLNPSPLKSLGENLKDQYLTVEDFKEGTRKQNPKLLYNLTDLYKDAHAQLQINAETAKKHIQNLYEEGFITYPRSSSRHLPTEQVDRVKGVMQALAKSRYSLLVQSVDIDAIDIKHKTFDDDLVSSHFAIIPTTKQYQEEGRPEIEKQLYSLVVKRFVGNFMRPAVYLVRDVSLIDAMGNTYQIKESVLREKGFLEVFQEEVKEESVETFKVPILQKGQELQIYDFELQESKTKKPALHTESSILTFMETAGRKIDDEHLKELMKGKRIGTVATEAAFIPVLHEKNFIDIEKGKIITTPIGRAFIEQFPVQQIKDPLYTAEMEGMIHRIEKNEMSYENFIAQTNAFVQKITQEIIRIPDTVSYNLIETWKKQIEVCQCPCGNGIILDRGKFFGCSNHPNCNKGLPKRVKEKTIPTAQVKKLFEENKTDIIKGFKSNGKEFSAYLAFVNGEVSFNLPSVEELSLGQCPKCQKGKILNRKTFFGCSEYQNGCDFMLPAKIKGKKLSDSQIKKLVNNHVTDFINGFSGEKGEFTAAIRLKTDLSICFEFPTTDDRTVGKCPLCQSRVIIGKTNYLCEQYKRGCDFIVSGMILEKRITASQIKKLLEKNMTDTVKGFVSKKTGKSFDAKLTYDSTQKRVTFIYEKKK
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity).
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I, Omega-protein, Relaxing enzyme, Swivelase, Untwisting enzyme.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: PLSY_BURVG
Sequence: MQILLAALVAYLIGSVSFAVIVSAAMGLADPRSYGSKNPGATNVLRSGNKKAAILTLVGDAFKGWLAVWLARHFGMPDVAVAWVAIAVFVGHLYPVFFRFQGGKGVATAAGVLLAVHPVLGLATALTWLIVAFFFRYSSLAALVAAVFAPVFDVFLFGTRNNPIAWAVLAMSVLLVWRHRGNIAKLLAGQESRIGDKKKAAADGGAQGGGKV
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GPDA_ORITI
Sequence: MKIAIIGAGAWGTAIAMLLARNNYRVTLYTRHSAHTQEINQLHTNKKYLPNIILPNIIKATSSFSDIVDHEIIIIVTPSDQVRATIKNLKQHGISNNAIIGIASKGLDHNQSKLLSDVVKDYLANNPLFIIAGPNLANEVAQGLPCALTIAAIQKEVRFNISTLFHSPNVITSTTEDIITIQVASAFKNIIAIIAGIIIAKQYGQNCKASIITQGIKEIVAFARAAGSTNPDISEFAVIGDLILTSYAITSRNTKFGYDLGQYEYYTDLSNNTNPNLIEGIKAAKILYPLTVKLNLNCHIIYCAYSILHNGGKISSAIECMLKKINHETK
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGS_MAIZE
Sequence: VTDSVIGEGCVIKNCKIHHSVVGLRSCISEGAIIEDTLLMGADYYAETEADKKLLAENGGIPIGIGKNSHIRKAIIDKNARIGDNVKILNADNVQEAARETDGYFIKGGIVTVIKDALLPSGTVI
What is the function of this protein?
This protein plays a role in synthesis of starch.  It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase small subunit, ADP-glucose pyrophosphorylase, ADP-glucose synthase, AGPase B, Alpha-D-glucose-1-phosphate adenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid, amyloplast. Note=Found in the chloroplast in leaf. Found in the plastid in the developing endosperm.
Protein: CLCC1_DANRE
Sequence: MKLSSSSSFGLCILVVFFCFVVIESAKIRIDGYNDEAWIDPYDMLNYDPTTKRMRKSTESESYQNVPTKRREFNSESCDVPKCPDEHECIKKLHILQKEFDEQKSKSTATLSKPVCLPVFKRFLSKLLKETSKLGLPDDGITAMHYDAEVKLSKQSLAEIQKLLNDEDGWTTGAMDEALSQILVQFKLHDYEAWKWRFEDTFHVDVDTVLKVSLIVLIIVAIICTQLWSVVSWFVQFRRMFAVSFFISLIWNWFHLYMLAFAEHKKNIVQVESFNAKCTGLKQLNWQDSLSEWYRRTWTLQDDPCKKYYEVLVVNPILLVPPTKAITITITNFITDPLKHIGEGISEFLRALLKDLPVTLQIPVLIIIILAILIFVYGSAQAAIHQVARFPRLGWRQEQPPPAVGQRQNPQLRAHEEPWEGGDARQPLPMRQDNRGNHVGNRGDQGFRDANAPENREEDRSMDIRQEFSTKRTPVETLQATGNTFPDDETDSQQRTQELDSGANVEEEVKVEEKEKKESFSVDNKEQKETKSPDRSEPITSEPPSSIDVKTVGADQGNEHLMCTKRKWAAQNGFKLQVILCEINSEASADLPEEEECFSFKHPVQETQS
What is the function of this protein?
Seems to act as a chloride ion channel (By similarity).  Plays a role in retina development (PubMed:30157172).
What are the official names of this protein?
Chloride channel CLIC-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the chloride channel MCLC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein. Note=Within the endoplasmic reticulum (ER), localizes to the mitochondria-associated ER membrane, a zone of contact between the ER and mitochondrial membranes.
Protein: ATPD_PSEA7
Sequence: MAELTTLARPYAKAAFEYAQAHQQLADWSAALGVLAAVSQDDTVRQLLKEPQLTSSAKAQSLIDVCGDKLNAPAQNFVRTVAENKRLELLPTIAEMYEQLKAEQEKSVEVEVTSAFTLSKEQQDKLAKALSARLSREVRLHASEDASLIGGVIIRAGDLVIDGSVRGKLAKLAEALKS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.