PharMolix/UniProtQA huggingface dataset:
Protein: Y2124_ARCFU
Sequence: MNYFLIFLTLLVAVIVEKIEELVAIRFFSSYVLDIARMEAEIEEYKELSMLAMLSGDREAYRGFQDMMNEIYGRVFFRKISFFTPLYFLLLSPYIVALQFLGVENSLSIVLPVAVLYFSAKLFYGMVRDFVKSYVDYRKANN
What are the official names of this protein?
Uncharacterized protein AF_2124.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MURA_MANSM
Sequence: MEKFRVYGQSRLTGTVDISGAKNAALPILFASILAEEPVILTNVPDLKDVETTFKILRKLGVNVECAEEPGKVLIDAGNINQFVAPYELVKTMRASIWALAPLLSRFHEGQVSLPGGCTIGARPVDMHISGLEKMGAAIELDEGYVKATVNGRLKGARIYMDKVSVGATLSIIMAATLAEGKTVIENAAREPEVVDTAIFLNAMGAKISGAGTDTISIEGVERLAGCRHRIVPDRIETGTFLVAAAISGGRITCRGTKADTLEAVIEKLREAGMQIDITEDSITLDSLGQRPKAVNIRTMPHPGFPTDMQAQFTLLNVVAEGTSKITETIFENRFMHIPELIRMGAKAEIEGNTAICHGVEHLSGAQVMATDLRASISLVLAGCIASGETIVDRIYHIDRGYERIEEKLRGLGARIERFSD
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_MYCGA
Sequence: MNKVHSEIKTQSFNPFWNAATLKEKSRIDPNLKKALSYLWKFLKICVFLFLTVIGLWGCTQTYSEPWTVSNPRIGVGLEIGYNYGVTGDYRYDLTSSNIGPYFSFANYQLSYGPFLAWFVWPASQIILPILYQTRVPLTQGIDYGLNTILAILILLFIIRLITIGITLNSTLNTERMGEVQGKIAEINAKYKNATDTQSKKMKQIEVMHIYKKHKIKPAALFVQGFVTIPIFLIVYKMVSLTRPIKATILFGIWDLSVTPGTEIISDISRNWVYIFFVLLVVPMQIVSQWLPQFWATRRNRNAKTTSQKGLEQLKKTRRIQWILIFVFALFPVITPSAVGLYWFLNSIFTILQSYITHVFIVKRRQRTKTISRLDQILNRELD
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins (By similarity).
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HTPG_YERPN
Sequence: MNMKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPELFEGDGELRVRLSFDKEKRTLTLSDNGIGMTRDEVIDNLGTIAKSGTKAFLESIGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGAPADTGVFWESAGEGDYTIADITKDERGTEITLHLREGEDEYLDDWRLRSVISKYSDHIALPVEIQVKNEEDGTVTWEKINKAQALWTRGKAEISDDEYKAFYKHIAHDFTDPLSWSHNRVEGKQEYTSLLYIPAQAPWDMWNRDHKHGLKLYVQRVFIMDEAEQFMPNYLRFVRGLIDSNDLPLNVSREILQDSRITQNLRSALTKRVLQMLEKLAKDDAEKYQQFWQQFGMALKEGPAEDGSNKETIAKLLRFASTHTDSSAQTVSLEDYVSRMAEGQEKIYYITADSYAAAKSSPHLELFRKKGIEVLLLSDRIDEWMMSYLTEFEGKAFQSVSKADDSLNKLADEENPEQQEAEKALEPFVERVKTLLGERVKDVRLTHRLTDTPAIVTTDADEMSTQMAKLFAAAGQQAPEVKYIFELNPDHGLVKRAAEVTDDTQFAQWVELLLDQALLAERGTLEDPNQFIRRMNQLLTA
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_RUEST
Sequence: MAQTFLGQKRLRKYYGKIREVLDMPNLIEVQKSSYDLFLRSGDAPQPLDGEGIKGVFQSVFPIKDFNETSVLEFVNYALERPKYDVDECMQRDMTYSAPLKVTLRLIVFDVDEDTGAKSVKDIKEQDVFMGDMPLMTPNGTFIVNGTERVIVSQMHRSPGVFFDHDKGKTHSSGKLLFACRIIPYRGSWLDFEFDAKDIVFARIDRRRKLPVTTLLYALGLDQEGIMDAYYNTVNFKLEKSRGWVTPFFPERVRGTRPTYDLVDAATGEIICEAGKKVTPRAVKKMIDEGNITELLVPFEHIVGKYVAKDIINEENGAIYVEAGDELTLEYDKDGDIIGGSVKELLDAGITDIPVLDIDNVNVGPYMRNTMAQDKNMSRETALMDIYRVMRPGEPPTVEAASALFDTLFFDSERYDLSAVGRVKMNMRLALDAEDTQRTLRKEDIVACIKALVELRDGKGDVDDIDHLGNRRVRSVGELMENQYRVGLLRMERAIKERMSSVEIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRMCPIETPEGPNIGLINSLATFARVNKYGFIETPYRVVKDGQVTDEVHYMSATEEMRHTVAQANANLDEDNRFVNDLVSTRQSGDYTLAPNESVDLIDVSPKQLVSVAASLIPFLENDDANRALMGSNMQRQAVPLLRAEAPLVGTGIEEIVARDSGAAIMAKRAGVIDQIDAQRIVIRATSDLELGDAGVDIYRMRKFQRSNQNTCINQRPLVKVGQTVEKGEVIADGPSTDMGELALGKNVVVAFMPWNGYNYEDSILISERIARDDVFTSIHIEEFEVAARDTKLGPEEITRDIPNVGEEALRNLDEAGIVYIGADVEPGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSLRVKPGDYGTVVEVRVFNRHGVEKDERALQIEREEVERLARDRDDELGILDRNIYARLRDLLLGKTAVKGPKGVRGNTVIDEDLLDNQLTRGQWWMLALEEEQDAQILEALNEQYEAQKRALDARFEDKVEKVRRGDDLPPGVMKMVKVFIAVKRKLQPGDKMAGRHGNKGVISRVVPMEDMPFLADGTPVDFCLNPLGVPSRMNVGQILETHMGWAARGLGLKIDDALQDYRRTGDLTPVRDAMREAYGEDVYEEGISSMDETQLIEAAGNVTRGVPIATPVFDGAKEDDVNDALVRAGFDQSGQSILFDGRTGEQFARPVTVGIKYLLKLHHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYESIVKGEDNFEAGVPESFNVLVKEVRGLGLNMELLDAEVEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: WECH_ECOLI
Sequence: MQPKIYWIDNLRGIACLMVVMIHTTTWYVTNAHSVSPVTWDIANVLNSASRVSVPLFFMISGYLFFGERSAQPRHFLRIGLCLIFYSAIALLYIALFTSINMELALKNLLQKPVFYHLWFFFAIAVIYLVSPLIQVKNVGGKMLLVLMAVIGIIANPNTVPQKIDGFEWLPINLYINGDTFYYILYGMLGRAIGMMDTQHKALSWVSAALFATGVFIISRGTLYELQWRGNFADTWYLYCGPMVFICAIALLTLVKNTLDTRTIRGLGLISRHSLGIYGFHALIIHALRTRGIELKNWPILDIIWIFCATLAASLLLSMLVQRIDRNRLVS
What is the function of this protein?
Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units.  Catalyzes the acetylation of both cyclic ECA (ECA(CYC)) and phosphoglyceride-linked ECA (ECA(PG)).
What are the official names of this protein?
O-acetyltransferase WecH.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CH60_YERPS
Sequence: MAAKDVKFGNDARIKMLRGVNILADAVKVTLGPKGRNVVLDKSFGSPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQSIITEGLKAVAAGMNPMDLKRGIDKAVIAAVEELKKLSVPCSDSKAIAQVGTISANSDSTVGELIAQAMEKVGKEGVITVEEGSGLQDELDVVEGMQFDRGYLSPYFINKPETGSIELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTAGTVISEEIGLELEKTTLEDLGQAKRVVINKDTTIIIDGVGDEAAIQGRVAQIRQQIEDATSDYDKEKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRAAHAIAGLKGDNEDQNVGIKVALRAMESPLRQIVVNAGEEASVIANKVKAGEGSFGYNAYTEEYGDMIAMGILDPTKVTRSALQYAASIAGLMITTECMVTDLPRDDKGADMGAGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EVGA_ECOLI
Sequence: MNAIIIDDHPLAIAAIRNLLIKNDIEILAELTEGGSAVQRVETLKPDIVIIDVDIPGVNGIQVLETLRKRQYSGIIIIVSAKNDHFYGKHCADAGANGFVSKKEGMNNIIAAIEAAKNGYCYFPFSLNRFVGSLTSDQQKLDSLSKQEISVMRYILDGKDNNDIAEKMFISNKTVSTYKSRLMEKLECKSLMDLYTFAQRNKIG
What is the function of this protein?
Member of the two-component regulatory system EvgS/EvgA.  Regulates the expression of emrKY operon and yfdX.  Seems also to control expression of at least one other multidrug efflux operon.
What are the official names of this protein?
DNA-binding transcriptional activator EvgA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COQ4_PHANO
Sequence: MAKRVCVGDLRKLAGSVSTPSRCILPPHARCFSVLNRPPPNYEGHIPLTVIERLGLAVGSGLGSFLDPRRADLIASFGEATAQPHFIYKLRDRMLLNPTGRRILRDRPRLTSTSLDIPRLRQLPPNTLGYVYALWLDREGVSPDTRATVQYIDDEECAYVMQRYRECHDFYHALVGLPVFREGEVALKAFEFANTGLPMTGLAVFSAFTLKKAEWRRFWDIYGPWATRNGAQSDDVINIYWEEELETDIDQLRTRLGIEKPPDLREMRKAEREAQKKDKEAKETMTRAAV
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ4, mitochondrial, Coenzyme Q biosynthesis protein 4.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: Y2219_SULIL
Sequence: MKRLPAVAGSFYESDPKKLKMQIEWSFRHNIGPRDIPKQTYEKKKRDNLFFVVPHAGYIYSGPVAAHSYYYLVSEGRPDVVIILGPNHTGLGSYVSAWPKGEWETPLGSVKIDEEILMQLVKESEVIDLDEKSHLYEHSIEVQLPFLQYFFDDDFKIVPIVIMMQTLEIAEFLADAIYNVMQKNPDKDIVVLASSDMNHYDPHEITVKKDVEAIEKIQQLDYKGLYEVVEGKDVTLCGYGPIMVNLILAKKFGKKAYILKHATSGDTSGPKDSVVGYLAARFGS
What are the official names of this protein?
MEMO1 family protein LS215_2219.
What is the protein family that this protein belongs to?
Belongs to the MEMO1 family.
Protein: RHAS_ECO5E
Sequence: MTVLHSVDFFPSGNASVAIEPRLPQADFPEHHHDFHEIVIVEHGTGIHVFNGQPYTITGGTVCFVRDHDRHLYEHTDNLCLTNVLYRSPDRFQFLAGLNQLLPQELDGQYPSHWRVNHSVLQQVRQLVAQMEQQEGENDLPSTASREILFMQLLLLLRKSSLQENLENSASRLNLLLAWLEDHFADEVNWDAVADQFSLSLRTLHRQLKQQTGLTPQRYLNRLRLMKARHLLRHSEASVTDIAYHCGFSDSNHFSTLFRREFNWSPRDIRQGRDGFLQ
What is the function of this protein?
Activates expression of the rhaBAD and rhaT operons.
What are the official names of this protein?
HTH-type transcriptional activator RhaS, L-rhamnose operon regulatory protein RhaS.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_BORDL
Sequence: MKRTYQPSRVKRNRKFGFRARMKTKSGRLILARRRAKGRSKLTVSDEKKKY
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: PANB_BRUSI
Sequence: MSAPVTRKRLTPKVIQAMKGECPIVSLTAYTTPVARLLDPHCDLLLVGDSLGMVLYGMESTLAVTLDMMIMHGQAVMRGTSHACVIVDMPFGSYQESKEQAFRNAARVMQETGCDGVKLEGGEEMAETVAFLVRRGIPVFGHVGLMPQQVNTVGGFRSLGRGDDEVGKIRRDAQAIAQAGAFAVVIEGTVEPLAREITALIDIPTVGIGASSACDGQVLVSDDMLGLFQDFTPRFVKRFAHLAPQVSQAAEAYAEEVRARRFPGPEHVFGAKPGA
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_VIBCM
Sequence: MATGKIVQIIGAVVDVEFPQSEVPSVYDALNVVDSKERLVLEVQQQLGGGVIRAIVMGSSDGLRRGMTVQNTGAPISVPVGTKTLGRIMNVLGDAIDERGDIGAEEVYSIHRPAPSYEEQSSATELLETGVKVIDLICPFAKGGKIGLFGGAGVGKTVNMMELINNIALQHSGLSVFAGVGERTREGNDFYHEMQEAGVVNVEQPELSKVAMVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKKGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLNRNIAAMGLYPAIDPLDSTSRQLDPLVVGQEHYDVARGVQATLQRYKELKDIIAILGMDELSEADKQVVARARKIERFLTQPYHVAEVFTGDPGVYVPLKETLRGFKGLLAGDYDDIPEQAFMYCGTIDDAIENAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: VATL2_CAEEL
Sequence: MSYDLETAERAAYAPFFGYMGAASAQIFTVLGAAYGTAKSAVGICSMGVMRPELIMKSVIPVIMAGIIGIYGLVVAMVLKGKVTSASAGYDLNKGFAHLAAGLTCGLCGLGAGYAIGIVGDAGVRGTAQQPRLFVGMILILIFSEVLGLYGMIVALILGTS
What is the function of this protein?
Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  Involved in necrotic cell death (PubMed:22157748).  Required along with other vacuolar ATPase components for the removal of protein aggregates which form in immature oocytes in the distal gonad (PubMed:29168500).  This removal occurs as the oocytes mature and move to the proximal gonad, is triggered by the introduction of sperm through mating and occurs before fertilization (PubMed:29168500).  The introduction of sperm triggers V-ATPase accumulation in proximal oocytes and induces lysosomal acidification which leads to engulfing of protein aggregates by lysosomes and subsequent clearance of the aggregates (PubMed:29168500).  Lysosomal acidification also leads to changes in mitochondrial morphology and function (PubMed:29168500).  Mitochondria in distal immature oocytes are fragmented, produce high levels of reactive oxygen species (ROS) and have high membrane potential, indicative of metabolic inactivity (PubMed:29168500).  In contrast, mitochondria in proximal mature oocytes are tubular with lower ROS levels and membrane potential, indicative of an active metabolic state required for aggregate mobilization before clearance (PubMed:29168500).
What are the official names of this protein?
V-type proton ATPase 16 kDa proteolipid subunit c 2, V-ATPase 16 kDa proteolipid subunit c 2, Vacuolar proton pump 16 kDa proteolipid subunit c 2.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase proteolipid subunit family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PROTO_POLPI
Sequence: ILGTILGLLKSL
What is the function of this protein?
Potent antimicrobial peptide that is active against both Gram-positive and Gram-negative bacteria (B. subtilis (MIC=15 ug/ml or 4-16 uM), S. epidermidis (MIC=8-16 uM), S. aureus (MIC=15 ug/ml or 4 uM), E. coli (MIC=8-64 uM) and P. aeruginosa (MIC=64-128 uM)) (PubMed:16129513, PubMed:22450985, PubMed:23836163, PubMed:30534613).  Also shows cytotoxicity towards HEK293 cells (32 uM) (PubMed:30534613).  Adopts an amphipathic alpha helical conformation, that may allow to partition into the target membrane (PubMed:21745529, PubMed:23836163).  Acts by disrupting bacterial membrane (PubMed:21745529, PubMed:22450985).  Also acts in inflammation since it is chemotactic for polymorphonucleated leukocytes (PMNL) (PubMed:16129513).  Shows potent antitumor activity against prostate (PC-3) and bladder (Biu-87) cancer cell lines (PubMed:21745529).  Causes a reduced hemolysis to mammalian erythrocytes (HC(50)=50 uM) and has no mast cell degranulation activity at physiological concentrations (PubMed:16129513, PubMed:30534613).  In addition, when tested in vitro on the parasite Trypanosoma cruzi (responsible of the Chagas disease), is able to reduce the number of the three forms (epimastigote, trypomastigote and amastigote), probably acting through the apoptotic cell death pathway (PubMed:32360153).
What are the official names of this protein?
Polybia-CP, Pol-CP-NH2, Polybia chemotactic peptide.
What is the protein family that this protein belongs to?
Belongs to the MCD family. Protonectin subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: RIMM_ALKCK
Sequence: MTNWYNVGRLVNTHGVRGEVRVLSNTDFPEERYANGSVLKVAKSPQAEGTLVTVRSHRTHKNFDLLTFEGYNSINEVECFKGSYLYVSEDQLSELDEHEYYYHEIIGCTVVDEEGTKLGKIKDIIETGANDVWVVDRQQRKDLLLPYIEEVVKEVDVENKRIRVHIMEGLDDE
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPPH_GLAP5
Sequence: MIDFDGYRPNVGIVICNKQGQVLWAKRFGQNSWQFPQGGINEGENIEQAMYRELYEEVGLAKKDVRLLWASKYWLRYKLPKRLVRNEQTQPVCIGQKQRWFLLQLVADEGAINLKTSKTPEFDGWRWVSFWYPVRQVVSFKRDVYRKVMKEFAQVLMGEQKKVESEKNRDNKEFTHERKEFRTQPKRELRKPYRVFKGKK
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: EFM4_YEAST
Sequence: MKRSEKKSMSSALKNGIMERTQPEKVVQMQGTADLSTSKLGTKKYWDELYALELENFRRNPQDTGDCWFSDSDAEQKMIDFLVDNIGAYRISENASVVDLGTGNGHMLFELHQTEFQGKLVGIDYSEESVKLASNIAEATGVDNFISFQQADIFSGDWKPGKYDIVLDKGTLDAISLSGMKINGKLDVVDVYAGVVERILKKDGIFLITSCNFTQDELVKIIETDNLKMWKTIKYPVFQFGGVQGATICSVAFVKQN
What is the function of this protein?
S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that mono- and dimethylates elongation factor 1-alpha (TEF1 and TEF2) at 'Lys-316'.  May play a role in intracellular transport.
What are the official names of this protein?
Protein-lysine N-methyltransferase EFM4, Elongation factor methyltransferase 4, Secretion and early endocytosis protein 1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_ANADE
Sequence: MDANLRRKLDELPAEPGCYLMKDRAGEVVYVGKASSLRSRVRSYFDAGRGDQRAFVALLDGLLGDLEVIVTRSEKEAVLLENELIKKHRPRFNVRLRDDKDFIVLKLDERHPYPRLEVRRAREKRQPGARYFGPYSSASSIRETLRMVNRHFQLRTCSDHVFDHRKRPCILYQIHRCPAPCVYEVPAEEYRQSVEDAVEFLEGREGELVERLRGRMAGAAEGLRFEEAARLRDQLQAVERSLEKQRVLMSDRGDRDVIGLYREGPDLVVQVLSMRAGKLQDAQAHPFREQEFPAEEILSSFLSLYYEHTDAPDEILVPLEPVQAEALADVLSERRGRRVRLLTPQRGAKADLLDVARRNAEQGFRAWHEHDERREQALASLAKALHLARPPRWMECYDISTFQGALAVGSGVSMKDGEPDKANYRRYKVKAVAGQDDFAMLHEVVTRRLRRALGEGQLPDLIVIDGGKGQLNAALAAAKDLGVPTRPSPGNPDAPFVELVGLAKSRLVDGPALGTARVVARRGRRAEARLADAAEAAEKGFVSELARSPERVFLPGRKDPVVLRQNSAELFLLARLRDEAHRFAITFHRKLRRERNFQSVLEEIPGIGEGRKRALLRHFGALRRVREATPEEIAQVEGFGPRQAAAVHAFFHRPDAPPAAADEPSGAPEGTPAGGPAEAIPDAAIAATEAEIDAALADEDASPEPAA
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAS_ABIBA
Sequence: MALPVYSLKSHIPITTIASAKMNYTPNKGMITANGRSRRIRLSPNKIVACAGEADRTFPSQSLEKTALFPDQFSEKNGTPSNFTPPNREFPPSFWNNDIINSITASHKVQTGDRKRIQTLISEIKNVFNSMGDGETSPSAYDTAWVARIPAVDGSEQPQFPQTLEWILQNQLKDGSWGEEFYFLAYDRLLATLACIITLTIWRTGNVQLHKGIEFFRKQVVRMDDEADNHRPSGFEIVFPAMLNEAKSLGLDLPYELPFIEQMVKKREAKLKMITTNVLYTIQTTLLYSLEGLHEIVDFDKIIKLQSKDGSFLGSPASTAAVFMQTGNTKCLEFLEFVLRKFRNHVPSDYPLDLFERLWVVDTVERLGIDRHFKKEIKDALDYVYSCWDERGIGWAKDSPIADIDDTAMGLRILRLHGYNVSPDVLKTFKDENGEFFCFMGQTQRGVTDMLNVYRCSQVAFPGETIMEEAKLCTERYLRNALENADAFDKWAIKKNIRGEVEYALKYPWHRSMPRLEVRSYIGNYGPNDVWLGKSLYMMPYISNEKYLELAKLDFNSVQSLHQEEIRELVRWCKSSGFTELKFTRDRVVETYFAVASSMFEPEFSTCRAVYTKISVLLVILDDLYDGYGSPDEIKLFSEAVKRWDLSLLEQMPDHMKICFLGLYNTVNEVAEEGRKTQGHDVLGYIRNLWEIQLAAFTREAEWSQGKYVPSFDEYIENAQVSIGVATILLITILFTEEDDILSHIDYGSKFLRLASLTARLANDIKTYQEERAHGEVVSAIQCYMKDRPEITEEEALKYVYGRMVNDLAELNSEYLKSNEMPQNCKRLVFDTARVAQLFTMEGDGLTYSDTMEIKEHIKKCLFEPAT
What is the function of this protein?
Involved in the biosynthesis of cis-abienol, a labdane diterpene that can be used as synthesis precursor of ambergris substitution fragance products.  Bifunctional class I/II enzyme in which both the bicyclization and water capture occur in the class II active site, resulting in an intermediary labda-13-en-8-ol diphosphate, which undergoes cleavage of the diphosphate group and final deprotonation at the class I active site.  No activity with copalyl diphosphate as substrate.
What are the official names of this protein?
Bifunctional cis-abienol synthase, chloroplastic, Diterpene synthase TPS4, AbdiTPS4.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsd subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YBY5_SCHPO
Sequence: MKTTMLMLVLLVCSYIHYVCAQIRFVTPATTDSMDFTAISFSWEESNTGIPLEDITNTVFYICSGSMDAPQPCAVLYTSPSPSSISQAGPFAISQVFGPAGRLYFLWAQSTYAGGIVNDYTDFFTVNGLTGTFDNYEIYASLMALGVYPYVPTLTGFSTFLGVWPTGTMRDWYLSQTTGVLRTGPIQNRPDSTFTAATTDIQPLWETSSYSVFTTFAGPPIATSTVFASPTYMYTLYANYASTASKPTIIATPTAGLRRRDSWAQAAPKRGMRLGEHKRGLLYS
What are the official names of this protein?
Uncharacterized protein C11C11.05.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CA105_RAT
Sequence: MEKRELKTFVPKFDKIPWLSEASVVNKPLILSIPRRYRSSIVLTSYKKDMYLPHLLEDSDFISKARKNEHENLLPRNKQLCSTCRGYQEMKTLQPKIFKIPDHREPSPQNSVNHGEVSLHSQEQQLHACNDIPTESIRYRLPILGPRTAVFHRLLSDAYKTPQDTQYCAFPKKKGMSKTVKQITTPHAALYPCRSYSAI
What are the official names of this protein?
Uncharacterized protein C1orf105 homolog.
Protein: ALR_NITSB
Sequence: MAYVKLSEKALKHNLETVSKKAGGSDKIAAVLKDNAYGHGIEGFAKKISRLGIKKAVVRTYEEALKIADFFPYILILSDTPRHDSFHYAINDLDTLQVLEPGTKVHLKIDTGMHRNGIALEEIEKAFELLQKNRAHLTGVFTHFRSADELSSELFWQNEQWQTVKQHVIELIKKYNLQKPLFHAANSAALFRLGCEDDFARIGIALYGYTELDDLYEPPALEPVASLWAQKIASRELKKGSRVGYGGVFEAREDMIISTYDAGYADGIFRFQKEIEDGKILGRVSMDSILLEGEKKEICIFSDAKKMARKLGTISYELLVKMPAHLSRTWID
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: RPOA_BLOFL
Sequence: MQSFEKEFLKPRSINIEKISEIHSKITLEPLERGFGHTLGNALRRILLSSMPGCAITEVEIEGVLHEYGTKEGVREDVLEILLNLKTLAINMYVKDSIVLTLKKTGIGPVIASDIEYDSSIISIVNPNHIICCITDQDTSIIMRIKVQRGRGYVPAFSRFSSDDQHDLPIGRLLLDACYSPVERISYTVEAARVEKRTDLDKLIIDMETNGTIDPEEAIRRAATILSDQLSSFIDLKDVHQPEVKEEKPEFDPSLLNLVDDLELTVRSANCLKAESIHYIGDLVQKTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLDNWPPKHLSEQ
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.