PharMolix/UniProtQA huggingface dataset:
Protein: ARSJ_HUMAN
Sequence: MAPRGCAGHPPPPSPQACVCPGKMLAMGALAGFWILCLLTYGYLSWGQALEEEEEGALLAQAGEKLEPSTTSTSQPHLIFILADDQGFRDVGYHGSEIKTPTLDKLAAEGVKLENYYVQPICTPSRSQFITGKYQIHTGLQHSIIRPTQPNCLPLDNATLPQKLKEVGYSTHMVGKWHLGFYRKECMPTRRGFDTFFGSLLGSGDYYTHYKCDSPGMCGYDLYENDNAAWDYDNGIYSTQMYTQRVQQILASHNPTKPIFLYIAYQAVHSPLQAPGRYFEHYRSIININRRRYAAMLSCLDEAINNVTLALKTYGFYNNSIIIYSSDNGGQPTAGGSNWPLRGSKGTYWEGGIRAVGFVHSPLLKNKGTVCKELVHITDWYPTLISLAEGQIDEDIQLDGYDIWETISEGLRSPRVDILHNIDPIYTKAKNGSWAAGYGIWNTAIQSAIRVQHWKLLTGNPGYSDWVPPQSFSNLGPNRWHNERITLSTGKSVWLFNITADPYERVDLSNRYPGIVKKLLRRLSQFNKTAVPVRYPPKDPRSNPRLNGGVWGPWYKEETKKKKPSKNQAEKKQKKSKKKKKKQQKAVSGSTCHSGVTCG
What are the official names of this protein?
Arylsulfatase J, ASJ.
What is the protein family that this protein belongs to?
Belongs to the sulfatase family.
What are the subcellular locations of this protein?
Secreted.
Protein: KGUA_MARMM
Sequence: MSSDGYPAPIFRGRRRGVLLALSSPSGAGKTTLSKRLLSQNPDVVLSVSATTRKPRPGEVDGQDYHFISVDEFKKKIEDDEFFEWAEVFGRYYGTPKTPVMEAVEDGRDVVFDIDWQGAQALAAAAPDDAVRVFILPPSLALLEDRLRKRGQDTTEIIKDRMARAKDEISHWHEYDYVIVNDDFARALEKLNEILHAERLKRLRHPWLEEFVDAIMEQ
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSB1_STRAW
Sequence: MAGETVITVVGNLVDDPELRFTPSGAAVAKFRVASTPRTFDRQTNEWKDGESLFLTCSVWRQAAENVAESLQRGMRVIVQGRLKQRSYEDREGVKRTVYELDVEEVGASLKNATAKVTKTTGRSGQGGQGGYGGGGGGQQGGGWGGGSGGAPQGGGAPADDPWATGTPAGGNQGGGGGGGWGGSSGGSSGGSGGGYSDEPPF
What are the official names of this protein?
Single-stranded DNA-binding protein 1, SSB 1.
Protein: MATK_DANSP
Sequence: MEKFEGYSEKQKSRQQNFVFPLLFQEYIYAFAHDYGLNGCKPVEILGCNTKKFSSLLVKRLIIRMYQQNFWINSVNHPNQDLLLDRSNHFYSEFYSQILSEGFAIVVEIPFSLGELSYSQEKEIPKFQNLQSIHSIFPFLEDKFLHLHSISHIEIPYPIHLEILVQFLEYRIQDVPSLHLLRFFLNYYSNWNSLITSMKSFFLLKKENKRLFQFLYNSYVSEYEFFLLFLHKQSSCLPLTSSGTFLERIIFSRKMEHFGVMYPEFFRKTIWIFMDPLMHYVRYQGKAILASKGTLLLKKKWKSYLVNFSQYFFSFWTQPQRICLNRLTNSCFDFMGYLSSVPINTLLVRNQMLDNSFRISIRMKKFDTIVPATPLIGALSKAQFCTGSGHPISKPVWTDLSDWDILDRFGRICRNLFHYHSGSSKKQTLYRLKYILRLSCARTLARKHKSTVRTFMQRLGSVFLEEFFTEEEQVFSLMFIKTTHFSFHGSHSDRIWYLDIIRINDLVNPLTLN
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GPDA_STRA3
Sequence: MTKQKIAVLGPGSWGTALAQVLNDNGHEVRLWGNVVEQIEEINTSHTNQRYFKDITLDSKIKAYTNLEEAINNVDSILFVVPTKVTRLVAKQVANLLKHKVVIMHASKGLEPGTHERLSTILEEEISEQYRSDIVVVSGPSHAEEAIVRDITLITAASKDIGAAKYVQKLFSNHYFRLYTNTDVVGVETAGALKNIIAVGAGALHGLGYGDNAKAAIITRGLAEITRLGVQLGADPLTFSGLSGVGDLIVTGTSVHSRNWRAGDALGRGEKLEDIEKNMGMVIEGISTTKVAYEIAQNLNVYMPITEAIYKSIYEGANIKDSILDMMSNEFRSENEWH
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LID16_CAEEL
Sequence: MDSPFNFTRRRSHVVANERRDMIQPSSSIPRPITNNIWTLNDYLNFDKSDVHTGPPRSLEIKKLILDTLKEMPELWTQRCSKKPHWELLGFNILQRTGMRIGTCQLMETFRNARKHVNAKIRKCWKEGLSKAETEIKCSNWDLFENFRFFFEFKCRHWQFPDDCDDLVVELDTEEGIISNPSLPPNEVCDQNVEILQSATKESIMPDVPEHYLDFEQHLKAKIQQALNKHPGQEKLLKNAIFTTLNGIENRDHKSLEELFSSLSSNH
What are the official names of this protein?
Uncharacterized lin-8 family protein lido-16.
What is the protein family that this protein belongs to?
Belongs to the lin-8 family.
Protein: RIMP_MYCSS
Sequence: MAPEPKLRPTGLPSQEQVKELLDGEFARAGYEIENVVIDGGARPPRITVVVDGDRPLDLDTVASLSRSASEQLDRVDESGPGVTADAATYVLEVTSPGVDRPLTTEKHYRRARGRKVELTLSDGSQLTGRIGALTADGESVSLVVREGARANFSVRELPLEGIVKAVVQVEFSPPSQRELELTGQPREEAGA
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR11_GNEPA
Sequence: MALTKPKKIPRYRRNKPEIRKVDKGIIHIRASFNNTIITVTNVLGCVISWSSAGACGFKGPKKGSAFAAQKATENVIRMVVINRATVLITGCGKGRDAALRVIHQNYIPIHAVLDVTPTPHNGCRPPVKRRI
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RK6_PORPU
Sequence: MSRIGKKIVLLPTNISTQFDGQTITVNGPKGTLLRTLPEGITLEINDGTILVQTSGNSKRANQLHGLSRTLISNMIEGVSTGFSKKLQIQGVGYRSQIDNNNLILSVGYSHVVTIQPPQNIEIKVENNTSITVLGIDKEVVGQVASSIRSIRPPEPYKGKGIRYQGEVVRTKAGKAGKGK
What is the function of this protein?
Binds 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L6, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CINAL_SYNS3
Sequence: MADRSERSGVEILCVGTELLLGNILNGNARWLSEELATLGLPHFRQTVVGDNRDRLIALVQEIAQRSRVLIVTGGLGPTPDDLTTEAIAAAFSVPLEERVDVWSDIQEKARSRGRTPSPETRRQALLPVGAEVLWNPTGTAPGMIWTPVPGFSVLTFPGVPSEMKAMWKATAVPWFRSSGLSKGVFVSRLLHFWGIGESTLAEQVADLLEGVNPTVAPYAGRGEVKLRITACADVSSKAWVLVDQIEQELRQRTGNLCFGVDEDSLASVVLKRLGQTGQTLSVAESCTGGGLGAELTAVPGASSVMLGGVISYSNAVKRDLLSVPEDLLTQHGAVSAQVAEAMALGVRRLTGSDWALSITGIAGPDGGTPEKPVGLVFVGVAGPDGCSTEMLRLGPTRGREWIRIVSAGEVLNRLRLRLMVND
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: AARD_HUMAN
Sequence: MGPGDFRRCRERISQGLQGLPGRAELWFPPRPACDFFGDGRSTDIQEEALAASPLLEDLRRRLTRAFQWAVQRAISRRVQEAAAAAAAREEQSWTGVEATLARLRAELVEMHFQNHQLARTLLDLNMKVQQLKKEYELEITSDSQSPKDDAANPE
What are the official names of this protein?
Alanine and arginine-rich domain-containing protein.
Protein: QUEA_XANCB
Sequence: MKKSDFHYDLPEELIAQAPLAERAASRLLVVPPTPAAFSDRQVRDLPELLQPGDLLIFNDTRVIPARLFGQKASGGRVEILIERLLGGQQARAQIGASKSPKAGSVIALDAGGQAEVLGRDGEFYLLRFDIPAPLEHWLLDAGRLPLPPYIRREPGLDDRERYQTVFAREVGAVAAPTAGLHFDEALLARLRERGVEFGHVTLHVGAGTFQPVRVDALDKHVMHTEWLNVGAALVEQVRRTRARGGRVIAVGTTVVRSLESAWRKTDDAPHGELQPFAGETQIFILPGYRIRSVDAMVTNFHLPESTLLMMVSAFAGCDRIFAAYAHAIAQRYRFFSYGDAMLLWSREWGIGNGES
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAND_DESHY
Sequence: MFRTMMKSKIHRATVTEANLKYVGSITIDEELLEVADILPNEKVQVVNNNNGARLETYVIPGKRGERTVCLNGAAARLVQVGDEVIIIAYGIFTDEAARTYEPKVIFVDEGNNPVKIAHEEIHGQQS
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELO_BURCH
Sequence: MSFSRSAADAADTLPDLAATLGAPAERAFVTLGDAFHTRLPAAPLAAPYVVGFSDDVAQLLDLPPSIAAQPGFAELFAGNPTRDWPAHAMPYASVYSGHQFGVWAGQLGDGRALTIGELPGTDGRRYELQLKGGGRTPYSRMGDGRAVLRSSIREFLCSEAMHHLGIPTTRALTVIGSDQPVVREEIETAAVVTRVSESFVRFGHFEHFFSNDRPDLLRQLADHVIDRFYPACRDADDPYLALLEAATLRTADLVAQWQAVGFCHGVMNTDNMSILGVTIDYGPFGFVDAFDANHICNHSDTSGRYAYRMQPRIAHWNCYCLAQALLPLIGLQHGIADDDARAERAVDDAQAVLAKFPERFGPALERAMRAKLGLELEREGDAELANKLLETMHASHADFTLTFRRLAQISKHDASRDAPVRDLFIDREAFDAWANLYRARLSEETRDDAARAVAMNRANPKYVLRNHLAEVAIRRAKEKDFSEVERLAQILRRPFDEQPEHEAYAALPPDWAGSLEVSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: PYRF_SCHPO
Sequence: MDARVFQSYSARAEGMKNPIAKELLALMEEKQSNLSVAVDLTKKSEILELVDKIGPYVCVIKTHIDVVEDFDQDMVEKLVALGKKHRFLIFEDRKFADIGNTVKLQYASGVYKIASWAHITNCHTVPGEGIIQGLKEVGLPLGRGLLLLAEMSSKGSLATGSYTEKTLEWFEKHTDFCFGFIAGRRFPNLQSDYITMSPGIGLDVKGDGLGQQYRTPEEVIVNCGSDIIIVGRGVYGAGRNPVVEAKRYREAGWKAYQQRLSQH
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase, Uridine 5'-monophosphate synthase, UMP synthase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family.
Protein: RS2_BACCZ
Sequence: MSVISMKQLLEAGVHFGHQTRRWNPKMKRYIFTERNGIYIIDLQKTVKKVEEAFKVMRDIAAEGGDILFVGTKKQAQEAIKEEATRAGMYFVNQRWLGGTLTNFQTIQKRIKRLKDIERMQEDGTFEVLPKKEVVQLKKELERLEKFLGGIKDMKGLPSALFVVDPRKERIAVAEARKLHIPIIGIVDTNCDPDEIDHVIPANDDAIRAVKLLTSKMADAILEAKQGEETVTA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: THI4_SULIA
Sequence: MEVKIKQVDEVKISRYIIKETMEDWYQFVESDVVIVGAGPSGLSAAYYLAKAGLKTLVFERRLSFGGGIGGGAMLFHKLIIEKPADEILREVNVRLKEVEEGVYVVDSAEFMAKLATAAIDAGAKIIHGVTVDDVIFRENPLRVAGVAVEWTATQMASLHVDPIFISAKAVVDATGHDAEVISVAARKIPELGIVIPGEKSAYSERAEELTVINTGKVAEGLYAAGMAVTEVKGLPRMGPIFGAMVLSGKAVAEEITKDLLKSEIRT
What is the function of this protein?
Involved in the biosynthesis of the thiazole moiety of thiamine.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
What are the official names of this protein?
Thiamine thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
Protein: HLDD_THIDA
Sequence: MSQYTVVTGAAGFIGANIVKALNERGETNIIAVDNLTKADKFKNLTDCEIADYLDKTEFLSVVEEGVLDGSVAAIFHEGACSDTMETDGRYMMDNNYRYSGALLKFCQDEGAQFLYASSASVYGSGRVFSESRECESPLNVYGYSKFLFDQSVRRLWAERTAQIAGFRYFNVYGPREQHKGRMASVAFHFFNQYRAEGRVKLFEGCDGYPNGEQRRDFVSVEDVVRVNMWFLDHPEVSGIFNVGTGRCQSFNDVAVATVNACRAAEGQDALTLDEMQAQGLIGYVAFPEALKGKYQSYTEADTAALRRAGYDGSFYSVEEGTARYIERLLQS
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: YIDD_LACP7
Sequence: MKRILIAIVKLYRKYISPMKRVPTCRFTPTCSEYALEALQRYGAIRGSYLAVRRILKCHPFHKGGFDPVP
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NDK_ALKCK
Sequence: MERTYVMVKPDGVQRNLIGNIVSRFEQKGYTLAAAKLVTLSKETAETHYSEHRERPFFGELVSFITSGPVFAMVWEGEGVIKAARQLIGATNPSEAAPGTIRGDLAVNVGMNVVHGSDSPESAEREIAIFFKEEELNDYQKDSNKWV
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARC_RHOOB
Sequence: MSSTENPDSVAAARELEALRAEASALRRQLAESPEQLREMESRVDSLSIRNTKLMDTLKEARQQLIALREEVDRLGQPPSGYGVLLGVHDDQTVDVFTSGRKMRLTCSPNVDAETLKLGQTVRLNEALTIVEAGNFERVGEISTLREVLDDGQRALVVGHADEERIVWLAEPLATVFEESERESVAYDAESPTRKLRPGDSLLVDTKAGYAFERIPKAEVEDLVLEEVPDVHYDDIGGLGRQIEQIRDAVELPFLHKDLFHEYELRPPKGVLLYGPPGCGKTLIAKAVANSLAKKIAEARGQDSKEAKSYFLNIKGPELLNKFVGETERHIRLIFQRAREKASEGTPVIVFFDEMDSIFRTRGSGVSSDVETTVVPQLLSEIDGVEGLENVIVIGASNREDMIDPAILRPGRLDVKIKIERPDAESAQDIFSKYLVETLPVHSDDLAEFGGDRTACIRVMIERVVDRMYAESEENRFLEVTYANGDKEVLYFKDFNSGAMIQNIVDRAKKYAIKSVLDTGAPGLRVQHLFDSIVDEFSENEDLPNTTNPDDWARISGKKGERIVYIRTLVTGKNASASRAIDTESNTGQYL
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle.  May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
What are the official names of this protein?
Proteasome-associated ATPase, AAA ATPase forming ring-shaped complexes, ARC, Proteasomal ATPase.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: VM2JR_BOTJA
Sequence: FVANRMAHELGHNLGIDNDRDSCSCGANSCIMSATVSNEPSSRFSDCSLNQYSSDLINYYGCLLNEPLRTDIVSPPFCGNYYPEVGEDCDCGPPANCQNPCCDAATCKLTTGSQCAEGLCCDQCKFIKARQICRKGRGDNPDDRCTGQSGDCPRNS
What is the function of this protein?
Snake venom zinc metalloproteinase that inhibits ADP-induced platelet aggregation (probably by binding integrin alpha-IIb/beta-3 (ITGA2B/ITGB3)) and degrades fibrinogen.
What are the official names of this protein?
Zinc metalloproteinase-disintegrin jararin, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIb sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KDPC_PSEP1
Sequence: MTAYLRPALSLALLMTLVTGALYPLAVTGIAQVAFPNQANGSLVRDAQGQVRGSALIAQDFQGDGWFHSRPSAGAYATVASGASNLSPSNPALAERVKGDAATLYQAQQGPVPQALLTTSGSGLDPHLPPEALAYQIPRVAAARQLPVERLQALLEQATLHPLIGPPVVNVLALNQALEKLAIVR
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PSBA_SOLNI
Sequence: MTAILERRESESLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYRFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAAIEAPSTNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: Y3795_TRIEI
Sequence: MIITTTDVIQGSEVEEYLGIVTAEVVYGSNALRDFFAGIRDIIGGRTGSYEELFKQGQEEAIAELEKRARRMGANAVVGIEIDTGTINVDEKGALLLITAIGTAVKLA
What are the official names of this protein?
UPF0145 protein Tery_3795.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: RUVC_SERP5
Sequence: MTIILGIDPGSRVTGYGLIRQQGRQLTYVASGCIRTVVDDMPTRLKLIYAGVSEIITQFKPDFFAIEQVFMAKNPDSALKLGQARGVAIVAAVNQDLEVFEYAARQVKQTVVGTGAAEKAQVQHMVRSLLKLSANPQADAADALAIAITHCHLSQNVLRMSEGRLNLARGRLK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: TRM10_DEBHA
Sequence: MENQDTEQSQKRSGSEVEKDDFKRQKVVVPEGMTKREYKRQLKQQRWEETKDEYKQKKREKKKAARERRKERIKEAEANGETNEELYNYHQMKRAKVAPQEQIDTDVKIIMDCEFDSLMNDKEIVSLSNQITRSYSAKKHSTYDVQLDITSFNKNLKKRFEKAIPQYDKWTNVTFVENDKLEDILPMDDKQALSKYVYLTADTDEVIDTLEPHHTYIIGGIVDKNRYKNLCLNKAQSLGLKIGRLPIDKFIKMNGRQVLATSHVFELCCKWFENDKDWGKAFNEVLPPRKVKGKLTHGSDPEKSIEPSEVSEQPVSSEQSEQPVLSEQPVSSEQPVLSEQPVLSESSDEPSDEPSKGADH
What is the function of this protein?
S-adenosyl-L-methionine-dependent guanine N(1)-methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in cytoplasmic tRNA.
What are the official names of this protein?
tRNA (guanine(9)-N1)-methyltransferase, tRNA methyltransferase 10, tRNA(m1G9)-methyltransferase, tRNA(m1G9)MTase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. TRM10 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: IGHM_MESAU
Sequence: SPSSPTVFPLVSCESPLSDENLVAMGCLARDFLPSSISFSWNYQNKSEVNQGVRTFPTLRMGEKYAATSQVFLPPKSVLEGSDEYLVCKVHHGNTNKDLRVPIPVVTEMNPNVSVFVPSRDAFSGPAPRKSRLFCEASNFSPKQITVSWLRDGKPVKSGFTTEPVTPEDRGSGPRTYKVISTLTITESDWLNLSVYTCRVDHRGLTFWKNVSSTCAASPSTDIQAFPIPPSFVGIFLNKSATLTCLVTNLATYDTLNISWSSRSGEPLETKTKLTESHPNGTFSAIGEANVCVEDWDSGKEFVCTVTHRDLPSPQKKFISKPREMNKTPPAVYQQPLAREQLILRESATVTCLVKGFSPADIFVQWLQRGQPLSQDKYVTSAPMREPQAPHLYFTHSVLTVTEEEWNSGETYTCVVGHEALPHMVTERTVDRSTGKPTLYNVSLIMSDAGGTCY
What are the official names of this protein?
Ig mu chain C region.
Protein: P3C2G_HUMAN
Sequence: MAYSWQTDPNPNESHEKQYEHQEFLFVNQPHSSSQVSLGFDQIVDEISGKIPHYESEIDENTFFVPTAPKWDSTGHSLNEAHQISLNEFTSKSRELSWHQVSKAPAIGFSPSVLPKPQNTNKECSWGSPIGKHHGADDSRFSILAPSFTSLDKINLEKELENENHNYHIGFESSIPPTNSSFSSDFMPKEENKRSGHVNIVEPSLMLLKGSLQPGMWESTWQKNIESIGCSIQLVEVPQSSNTSLASFCNKVKKIRERYHAADVNFNSGKIWSTTTAFPYQLFSKTKFNIHIFIDNSTQPLHFMPCANYLVKDLIAEILHFCTNDQLLPKDHILSVCGSEEFLQNDHCLGSHKMFQKDKSVIQLHLQKSREAPGKLSRKHEEDHSQFYLNQLLEFMHIWKVSRQCLLTLIRKYDFHLKYLLKTQENVYNIIEEVKKICSVLGCVETKQITDAVNELSLILQRKGENFYQSSETSAKGLIEKVTTELSTSIYQLINVYCNSFYADFQPVNVPRCTSYLNPGLPSHLSFTVYAAHNIPETWVHRINFPLEIKSLPRESMLTVKLFGIACATNNANLLAWTCLPLFPKEKSILGSMLFSMTLQSEPPVEMITPGVWDVSQPSPVTLQIDFPATGWEYMKPDSEENRSNLEEPLKECIKHIARLSQKQTPLLLSEEKKRYLWFYRFYCNNENCSLPLVLGSAPGWDERTVSEMHTILRRWTFSQPLEALGLLTSSFPDQEIRKVAVQQLDNLLNDELLEYLPQLVQAVKFEWNLESPLVQLLLHRSLQSIQVAHRLYWLLKNAENEAYFKSWYQKLLAALQFCAGKALNDEFSKEQKLIKILGDIGERVKSASDHQRQEVLKKEIGRLEEFFQDVNTCHLPLNPALCIKGIDHDACSYFTSNALPLKITFINANPMGKNISIIFKAGDDLRQDMLVLQLIQVMDNIWLQEGLDMQMIIYRCLSTGKDQGLVQMVPDAVTLAKIHRHSGLIGPLKENTIKKWFSQHNHLKADYEKALRNFFYSCAGWCVVTFILGVCDRHNDNIMLTKSGHMFHIDFGKFLGHAQTFGGIKRDRAPFIFTSEMEYFITEGGKNPQHFQDFVELCCRAYNIIRKHSQLLLNLLEMMLYAGLPELSGIQDLKYVYNNLRPQDTDLEATSHFTKKIKESLECFPVKLNNLIHTLAQMSAISPAKSTSQTFPQESCLLSTTRSIERATILGFSKKSSNLYLIQVTHSNNETSLTEKSFEQFSKLHSQLQKQFASLTLPEFPHWWHLPFTNSDHRRFRDLNHYMEQILNVSHEVTNSDCVLSFFLSEAVQQTVEESSPVYLGEKFPDKKPKVQLVISYEDVKLTILVKHMKNIHLPDGSAPSAHVEFYLLPYPSEVRRRKTKSVPKCTDPTYNEIVVYDEVTELQGHVLMLIVKSKTVFVGAINIRLCSVPLDKEKWYPLGNSII
What is the function of this protein?
Generates phosphatidylinositol 3-phosphate (PtdIns3P) and phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) that act as second messengers (By similarity).  May play a role in SDF1A-stimulated chemotaxis (By similarity).
What are the official names of this protein?
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma, PI3K-C2-gamma, PtdIns-3-kinase C2 subunit gamma, Phosphoinositide 3-kinase-C2-gamma.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: PLCG1_RAT
Sequence: MAGVGTPCANGCGPSAPSEAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIEGSIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAATPLQIERWLRKQFYSVDRNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDFEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLETNTLRTGERPELCQVSLSEFQQFLLEYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDELVTFLFSKENSVWNSQLDAVCPETMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQHFRKVLGDTLLTKPVDIAADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSVMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEASGSTELHSSEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQDGGWWRGDYGGKKQLWFPSNYVEEMINPAILEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSISMPSVAQWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMAGGHCGYVLQPSTMRDEAFDPFDKSSLRGLEPCVICIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIKIDIFPAKENGDLSPFSGTSLRERASDASSQLFHVRAREGSFEARYQQPFEDFRISQEHLADHFDSRERRAPRRTRVNGDNRL
What is the function of this protein?
Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) (PubMed:7531435).  Plays an important role in the regulation of intracellular signaling cascades.  Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, EGFR, FGFR1, FGFR2, FGFR3 and FGFR4 (PubMed:7531435).  Plays a role in actin reorganization and cell migration (By similarity).
What are the official names of this protein?
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, Phosphoinositide phospholipase C-gamma-1, Phospholipase C-gamma-1, PLC-gamma-1.
What are the subcellular locations of this protein?
Cell projection, lamellipodium. Cell projection, ruffle. Note=Rapidly redistributed to ruffles and lamellipodia structures in response to epidermal growth factor (EGF) treatment.