PharMolix/UniProtQA huggingface dataset:
Protein: GYRA_CHLTR
Sequence: MLNKEEIIVPKNLEEEMKESYLRYSMSVIISRALPDARDGLKPSQRRILYAMKQLNLTPGVKHRKCAKICGDTSGDYHPHGESVIYPTLVRMAQDWAMRYPLVDGQGNFGSIDGDPAAAMRYTEARLTHSAIFLLEDLDKDTVDMVPNYDETKYEPVVFPSKFPNLLCNGSSGIAVGMATNIPPHNLGELIEATLLVLANSQTSIEDILEVMPGPDFPTGGIICGTEGIRSTYYTGRGKLRLRARMHVEENSDKQRENIILTEMPYNVNKSRLIEQIAELINEKTLTGISDVRDESDKDGIRVVLELKKGESSEVVINRLYKFTDVQVTFGANMLALDKNLPRTMNIHRMISAWIRHRMDVIQRRTRYELNKAEARAHILEGFLKALSCMDEVVKTIRESSNKEHAKQQLVELFSFSEAQALAILELRLYQLTGLEADKVQKEYSELLEKITYYRKVLAEEELVKDIIREELQELHKVHKTPRRTRIEMDAGDVRDIEDIISDESVIITISGDDYVKRMPVKVFREQKRGGQGVTGFDMKKGSDFLKAVYSASTKDYLLIFTNFGQCYWLKVWRLPEGERRAKGKPIINFLEGIRPGEQVAAVLNVKRFEQGEYLFLATKKGVVKKVSLDAFGSPRKKGIRALEIDDGDELIAARHIANDEEKVMLFTRLGMAVRFPHDKVRPMGRAARGVRGVSLKNEQDFVVSCQVVTEDQSVLVVCDNGFGKRSLVCDFRETNRGSVGVRSIVINQRNGDVLGAISVTDCDSILLMSAQGQAIRINMQDVRVMGRATQGVRLVNLREGDTLVAMEKLSINTESVETEENLAASVQSGQDTIEE
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIC1A_XENLA
Sequence: MAAQCESIGGDMNQSDPGSNSERSADSPVPGSEDDSPHDPEWREERFRVDRKKLETMLQAAAEGKGKSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKENVKEAKERIMSVLDTKSNRVTLKMDVLHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQAEKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGILQPIPDPNSPTIQQISQTYNLTVSFKQRSRVYGATVIVRGSQNNTSAVKEGTAMLLEHLAGSLATAIPVSTQLDIAAQHHLFMMGRNGCNIKHIMQRTGAQIHFPDPNNPLKKSTVYLQGTIDSVCLARQYLMGCLPLVLMFDMKEEIEIEPQCITQLMEQLDVFISIKPKPKQPSKSVIVKSVERNALNMYEARKCLLGLDSSGVTVTNQSTLSCPVPMNCHGLDILAAGLGLSGLGLLGPNTLSVNSTTAQNSLLNALNSSLSPLHSPSSAAPSPTLWAASLANNATGFSAIPHLMIPSAAQATLTNFLLSGVPNYGQNTPSPPPGLTPVDVHMNGIHSECKKVTSALNGHVKPTNMKYGTISSSSLGDKVLNTNLAEASRQSNNHSSAEEVNSKTDPEGCNDAFVEVGMPRSPSHSANTKDLKQMLNSTKAPCPTRQTVKLLHGTKNSHLHGERLLSDSEMSPMEGPVTDKKAPGSERAAERAAAQQNSERARLTSQSEYGTMQAYDYEQKKLLATKAMLKKPVVTEVRTPTNTWSGLGFSKSTPAETIKELRRANHVPYKPTMTTTYENSSLSRSNSREQLGNGSDSENWRERNGIDSSQNDYSSSIGSPKRKQNKSAEHYLSSSNYMDCISSLTGSNGCNLNSSFKGSDLPELFSKLGLGKYTDIFQQQEIDLQTFLTLTDQDLKELGISTFGARRKMLLAISELNKNRRKLFEPTNIRASFLEGGASGRLPRQYHTDIASVSGRW
What is the function of this protein?
Putative RNA-binding protein.  May be involved in regulating gene expression during embryonic development.  Seems to be involved in endoderm formation.  Ectopic expression results in endoderm formation in the absence of mesoderm induction.
What are the official names of this protein?
Protein bicaudal C homolog 1-A, Bic-C-A.
What is the protein family that this protein belongs to?
Belongs to the BicC family.
Protein: RL30_PSEE4
Sequence: MATVKVTLIKSVSGRIPNHKLCVKGLGLRRIGHTVEVQDTPENRGMINKAYYMLKVEG
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: BIOF_SYNC1
Sequence: MKLDHWQKTLDHLRDEEMLRGLKTVSGAQRDHVLLDGKDVLLLCSNNYLGLADHPALIEATCRATRDCGTGTGASRLVSGSMALHEELESKLAQFKGTQRALLFNAGYAANTGILQGLMGADDVIFSDSLNHASIIDGCRLSRAKTVVYPHRDTHALERLMAKEAPLRKGQWLIVTDGVFSMDGDLAPLPELVALKKRYDCLLMVDDAHGTGVLGDSGKGTGEYLGCLTDIDLHMGTLGKALGGFGAFVAGPDVVVQFLINRARSFIFSTSLPPGVVAAGIAALDIVNGSEGRQRRMNLQKLCTLFTGQLTESLPPEVRGETPIVPILTGDPEPTMRASAWLEAQGIFVQGIRPPTVPQGRCRLRATLMATHQVEDLLRAADLIRKVLSA
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
Putative 8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: BIOD_MYCTA
Sequence: MTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVTQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAASNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y037_MYCBO
Sequence: MADPGPFVADLRAESDDLDALVAHLPADRWADPTPAPGWTIAHQIGHLLWTDRVALTAVTDEAGFAELMTAAAANPAGFVDDAATELAAVSPAELLTDWRVTRGRLHEELLAVPDGRKLAWFGPPMSAASMATARLMETWAHGLDVADALGVIRPATQRLRSIAHLGVRTRDYAFIVNNLTPPAEPFLVELRGPSGDTWSWGPSDAAQRVTGSAEDFCFLVTQRRALSTLDVNAVGEDAQRWLTIAQAFAGPPGRGR
What are the official names of this protein?
Uncharacterized protein Mb0037c.
Protein: PGK_MYCTO
Sequence: MSVANLKDLLAEGVSGRGVLVRSDLNVPLDEDGTITDAGRIIASAPTLKALLDADAKVVVAAHLGRPKDGPDPTLSLAPVAVALGEQLGRHVQLAGDVVGADALARAEGLTGGDILLLENIRFDKRETSKNDDDRRALAKQLVELVGTGGVFVSDGFGVVHRKQASVYDIATLLPHYAGTLVADEMRVLEQLTSSTQRPYAVVLGGSKVSDKLGVIESLATKADSIVIGGGMCFTFLAAQGFSVGTSLLEDDMIEVCRGLLETYHDVLRLPVDLVVTEKFAADSPPQTVDVGAVPNGLMGLDIGPGSIKRFSTLLSNAGTIFWNGPMGVFEFPAYAAGTRGVAEAIVAATGKGAFSVVGGGDSAAAVRAMNIPEGAFSHISTGGGASLEYLEGKTLPGIEVLSREQPTGGVL
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMI_CHLSY
Sequence: MTRPRPVVLIIMDGWGIAPPGPGNAADLADTPHVDAWMANCPFTTLGASGLDVGLPEGQIGNSEVGHLNIGAGFVVYQELTRISKAIADGDFFTNPVLLQAIEHVKQRNSALHLMGLFGPGGVHAHEDHLHALLELAHRHHLQRVYLHLFLDGRDVLPRSALGFLDTLEGVIARLGVGTIATVSGRYYAMDRDKRWERTGRAYAALVDGVGEKAPSARAAIEASYARDVSDEFVLPTVIVTASGEPTATVRDGDAVIFTNFRPDRGRQLTRAFVDPDLNERIRQHYERQKAEGQPLPATIWQRERQLRDLCFVTMTQYEEGLPVLVAFPPRYVTNPLAAVISQAGLRQFHIAETEKYPHVTFFLNGGREEPFPGEDRQLIPSPKVATYDLKPEMSAPEVTEALLAAIDSDQYDFIVVNYANPDMVGHTGSIPAVIKACEAVDAGLARVVPAILERGGVALVIADHGNAEQMIDPETGGPHTAHTTNPAPCFLIGGAGYGKDAIELRHGGRLADVAPTLLELLELEPSPDMTGQSLIVRRA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: H1_DROHY
Sequence: MSDSVVAVSASPVTPQTASAEKKVAAKKPASASASKAKKTTAPPTHPPTQQMVDASIQNLKERGGSSLLAIKKYISATYKCDAQKLAPFIKKYLKNSVANGKLIQTKGKGASGSFKLSASSKKEPKPKVSSVEKKSKKVTSSAAAAKKKTISATKKPKGVADKKLSKAVVTKKSVDKKKAEKAKAKDAKKVGTIKAKPTTAKAKSSAAKPKTPKPKTTSAKPKKVVAAASPKKAAAKKPKAKTASATKK
What is the function of this protein?
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
What are the official names of this protein?
Histone H1.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: GLMM_BURO0
Sequence: MGRRYFGTDGIRGTVGEAPITPDFVLRLGYAAGKVLAGSADVAAGSRPTVLIGKDTRVSGYMLEAALEAGFSAAGVDVMLAGPMPTPGVAYLTRALRLSAGVVISASHNPYHDNGIKFFSADGNKLPDDTEAAIEAWLDKPLECAPSDGLGKARRLDDAAGRYIEFCKSTFPAAFDLRGLKLVIDCAHGAAYQIAPHVFHELGADVIPIGVAPNGFNINDGVGATAPDALVRAVRANHADLGIALDGDADRLQVVDATGRLYNGDELLYVLVKDRIATDGKVDGAVGTLMTNLAVEVALQREGVKFVRAAVGDRYVLEQLREHGWQLGAEGSGHILSLDRHSTGDGIVSALLVLAALKRSGRTLAQVLDGVTLFPQKLINVRMKPGADWKGSASIRAAIDAAEAALAGSGRVLIRASGTEPVLRVMVEAQQAADAVRHAETIADAVRAATT
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: ARSR2_HALSA
Sequence: MVQDATADGVMDASDACCAPPGNVDSDAMATDLQVLSAMGNDTRYELLRRIANADDGVCVCDLEATVGVSQSAVSQALSRLYTAGLVTRRKEGSWRYYEPTETTEVLLETLDDLRGNHE
What is the function of this protein?
Transcriptional repressor for the arsR2M operon.
What are the official names of this protein?
Putative arsenical resistance operon repressor ArsR2.
Protein: Y3905_ARATH
Sequence: MDVKDTGINRSDTPISDQDHDFRQWNHSSLDSNFLSLRSQIFEASYRRTDLIRVNHELFHERDALRRRNSELEAGILEEVMIREEMKRDLEVSKETVSELEGEAKEKTKLLSDIADYVRSMEDRLSKLIRCLNEENVPEEERGRKLETKEYNSKSILELVKEVVTKLETFQESTKKKKMELSRSVEFLEEENRDINVLLRAALFEKQTAEKQLKEMNDQKGLALLQIAGRGLQRIGFGFGLGESVEESSETGNIANEEEENGVVIAIEKTMKKLRQEVSQLKISLEESRLEEVGLRKVTEEQAQKLAENTVYINKLQNQEKFLAQNVEELVKAIREAESEVSRWREACELEVEAGQREVEVRDQLIAVLKSEVEKLRSALARSEGKLKLKEELAKAAMVAEEAAEKSLRLAERRIAQLLSRIEHLYRQLEEAESTERRRGKFRYVWCWPMWRFPTAASTAATATGSSSYTSNRALLRYDA
What are the official names of this protein?
Uncharacterized protein At3g49055.
Protein: CBPYA_TRIEQ
Sequence: MKFLTTGLLATAALAAAQEQQVLQAEDGMGQAPQRGSSIFDETLQKFQSSLEDGISHFWSEMKTNFKDYLPLISLPKKHTRRPDSEWDHVVRGADIESVWVQGADGEKRREIDGKLHNYDLRVKAVDPSKLGVDAGVKQYSGYLDDNDADKHLFYWFFESRNDPKNDPVVLWLNGGPGCSSLTGLFLELGPATIDKNLKVVSNPYSWNSNASVIFLDQPVNVGFSYSGSSVSDTVAAGKDVYALLTLFFKQFPEYATQDFHISGESYAGHYIPVFAAEILSHKNTNINLKSALIGNGLTDPLTQYPQYRPMACGEGGYPAVLDQGTCRSMDNSLERCLSLIETCYSSESAWVCVPAAMYCNSAILAPYQQTGMNPYDVRNKCEDMASLCYPQLNVITEWLNQKSVMQALGVEVESYESCNSGINRDFLFHGDWMKPYHRLVPSVLEKIPVLIYAGDADFICNWLGNQAWTDALEWPGHKKFAEAKLEDLKIVDNKNKGKKIGQVKSSGNFTFMRIFGAGHMVPLNQPEASLEFLNRWLRGEWH
What is the function of this protein?
Vacuolar carboxypeptidase involved in degradation of small peptides.  Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (By similarity).
What are the official names of this protein?
Carboxypeptidase Y homolog A.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: PSTB_MYCSS
Sequence: MAKRLDLKDLNIYYGSFHAVADVGLAVLPRSVTAFIGPSGCGKSTVLRTLNRMHEVIPGARVEGSVLLDGEDIYGPGIDPVSVRKTIGMVFQRPNPFPTMSIRDNVVAGLKLQGVRNRKTLDEVAEQSLKGANLWKEVKDRLDQPGGGLSGGQQQRLCIARAIAVQPDVLLMDEPCSALDPISTLAIEDLIDELKQDYTIVIVTHNMQQAARVSDQTAFFNLEATGKPGRLVEVDDTEKIFSNPTQKATEDYISGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: H32_TETTR
Sequence: MARTKQTARKSTGAKAPRKQLASKAARKSAPATGGIKKPHR
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.2.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: BACA1_BACC1
Sequence: MSNWYSKTKDQTLIDLETNEQHGLTEEIASERLKQYGSNELATKQKRTLWQRIFAQINDVLVYVLIIAALISAFVGEWADASIIALVVVLNAVIGVVQESKAEQALEALKKMATPKAIVKRDGELKEIPSEHVVPGDIVMLDAGRYIPCDLRLIETANLKVEESALTGESVPVDKDAIYHPSMQSDEQVPLGDQKNMAFMSTLVTYGRGVGVAVETGMNSQIGKIATLLHEADDDMTPLQKSLAQVGKYLGFVAVAICIVMFLIGFLQRRDTLEMFMTAISLAVAAIPEGLPAIVSIVLAIGVQRMIKQNVIIRKLPAVEALGSVTIICSDKTGTLTQNKMTVTHFYSDNTYDQLENLNVNNDVQRLLLENMVLCNDASYNNESQTGDPTEIALLVAGSTFNMQKDYLEKIHERINELPFDSDRKMMSTVHTYDESYYSMTKGAIDKLLPRCTHILKNGKIEVLTEADKNQILEAARAMSREALRVLSFAFKQYNSSNVDIDHLEENLIFIGLVGMIDPPRTEVKDSITECKKAGIRTVMITGDHKDTAFAIAKELGIAEDICEIMIGTELDNISDTELASKIDHLHVFARVSPEHKVKIVKALRAKGNIVSMTGDGVNDAPSLKQADVGVAMGITGTDVAKGAADVVLTDDNFSSIVKAVEEGRNIYRNIKKSILFLLSCNFGEIITLFLAILLGWATPLRPIHILWVNLITDTLPALSLGVDPEDPDVMKEKPRHAKESLFSGSVPFLIFNGVVIGLLTLIAFIAGAKFYTGDTNLFPLFPERIDEDALLHAQTMAFVVLSFSQLVHSFNLRSRTKSIFSIGIFTNKYLVFSLLIGVLMQVCIISIPPLANIFGVHALTLRDWGFVLLLSIIPLVVNEIIKLAKKN
What is the function of this protein?
Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
What are the official names of this protein?
Calcium-transporting ATPase 1, BACCA1.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYRH_STRMU
Sequence: MVKPKYSRVLIKLSGEALAGEKGVGIDIPTVQTIAQEIKEVHDSGIEIALVIGGGNLWRGEPASKAGMDRVQADYTGMLGTVMNALVMADALQHAGVDTRVQTAIAMQQVAEPYIRGRALRHLQKGRIVIFAAGVGSPYFSTDTTSALRAAEIEADAILMAKNGVDGVYNDDPRKNADAIKFNELTHMEVLKRGLKIMDSTASSLSMDNDIDLVVFNLNESGNIKRVIFGEQIGTTVTSRISDSE
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRP7_YEAST
Sequence: MGIEDISAMKNGFIVVPFKLPDHKALPKSQEASLHFMFAKRHQSSNSNESDCLFLVNLPLLSNIEHMKKFVGQLCGKYDTVSHVEELLYNDEFGLHEVDLSALTSDLMSSTDVNEKRYTPRNTALLKFVDAASINNCWNALKKYSNLHAKHPNELFEWTYTTPSFTTFVNFYKPLDIDYLKEDIHTHMAIFEQREAQAQEDVQSSIVDEDGFTLVVGKNTKSLNSIRKKILNKNPLSKHENKAKPISNIDKKAKKDFYRFQVRERKKQEINQLLSKFKEDQERIKVMKAKRKFNPYT
What is the function of this protein?
Plays an important role in the synthesis of 18S rRNA but is not required for the 5. 8S and 25S pathway.  Is necessary for the cleavage at site A2.  Is required for efficient association of RPS27 with the pre-ribosomal particle.
What are the official names of this protein?
Ribosomal RNA-processing protein 7.
What is the protein family that this protein belongs to?
Belongs to the RRP7 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ILVC_BRUO2
Sequence: MRVYYDRDADVNLIKSKKVVIVGYGSQGRAHALNLKDSGAANVRVALREGSATVQKAQADGFEVMNVADAAKWADLMMMATPDELQADIYRDHIHNNLRDGAAIAFAHGLNVHFGLIEPKKTVDVVMIAPKGPGHTVRGEYQKGGGVPCLIAIHQDASGNAHDLALSYASGVGGGRSGVIETTFKEECETDLFGEQAVLCGGVVELIRTGFEVLVEAGYAPEMAYFECLNEMKLIVDLIYEGGIANMNYSISNTAEWGEYVTGPRIITAETKAEMKRVLKDIQTGKFTSDWMQEWKAGAARFKGIRRLNDAHQIEEVGGKLRAMMPWIEKNKLVDKARN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: PMIR1_ARATH
Sequence: MSKVNSEESSSSQKLLKEVEKISEALYVNKNPRGSVAGSNKTPTKPLSRSNLAEPKEKKSFWNWPLRAINHVRNRRFNCCFSAQVHSIEGLPPIFQDLSLTVHWKRRDESLSTRPAKVSNGRAEFKDKLTHTCSVYGSRSGPHHSAKYEAKHFLLYVSLVGSPEIDLGKHRMDLTKLLPLTLEELQDEKSSGKWSTTFQLSGKANGATLSMSFGYTVVGDTRNPASSGSTQNFRSSSNVKQTSNNTGLTRAISAKSSLGNGKSASRRYDHSIVNRESHPLSQNMEEIKDLHEILPAVQSDLGSSVNTLYQKFDEEKVDPANESQFEFDVVTKHIEPVESISHEKEDANALQSELVTGNETVVPFEEIKKAGEVPTAGSDEVGAENFPLEEPLVNGNETDVPFELLKKAGEVPTAGRDEVGTEILPPEEPLVNGNETDVPFEELMITGEASIARSEEAVEIVTEELAPEEGNKISPKNEESVVPKDAEEVMNGEKDLKEMIMKDLESALKSVEMLEATASEDEEDRKKHGDKDKYFITPMKETVPSCSRDVAESVACEFLDMLGIEHSPFGLSSESEPESPRERLLREFEMETLAAGSLFDFSIEGDDPQLECDENFPNEYESDFEEGFDLASLVHDIEEEYQLEAQARVSHPRAKMLEGLETESLMREWGMNENTFQNSPPHNGRDAFHPADFPVKEPFDLPPLGDGLGPVVQTKNGGFLRSMNPLLFRNSKAGGSLIMQVSTPVVVPAEMGSGIMEILQKLATAGIEKLSMQANKVMPLDDITGKTMEEVLWETSPTIDIGDRDHVSERESGDASGFVRGGERRTSFAAKPKKFGSSSGNNNFDSEYVSLEDLAPLAMDQIEALSLEGLRIQSGMSDEDAPSDITAQSIGDISAFQGKSGCVGLEGAAGLQLLDIKDDGDDDDDGLMGLSLTLDEWMKLDSGDIGDEDEINERTSKILAAHHANPLNFIRKGSKGEKRKGKKGRKCGLLGNTFTVALMVQLRDPLRNYEPVGAPMLSLIQVERLFVPPKPKIYSTVSELKKTDEEEEADASDAKKEEKPMEEQGIPQYKITEVHLTGMKSETDKKPWGITTQQQQVQSGSRWLMANGMGKGNNKLPLMKPKLGSAKPGDKLWSVSGSGSKWKELGKMGKSNTHIRNPNVIMPK
What is the function of this protein?
Together with PMI1, necessary for chloroplast and nuclear photorelocation movements via the regulation of chloroplast-actin (cp-actin) filaments in pavement cells.
What are the official names of this protein?
Protein PLASTID MOVEMENT IMPAIRED 1-RELATED 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_LIMRJ
Sequence: MSYRKLGRTSSQRKALLRDLTTDLIVNGRITTTEARAKEVRKTADKMITLAKHGDLASRRKAAAFVRNVVADVKEDGDDIRVQSALQNLFEELAPKYADRNGGYTRILKTMPRRGDGAPMVILELVD
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: YQGF_BURCM
Sequence: MSGASARDATLLGFDYGEKRIGVAIGNALTRSARALVVIPNLNREHRFKAVGDLLAEWRPDALVVGLPMHPDGTPHEMTQQAKRFGNQLNGRFGLPVTWVDERYSSVEAEAGLRERNVRGRARAEMLDAEAARVILQQYLDQLSDHEHH
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COT1_HUMAN
Sequence: MAMVVSSWRDPQDDVAGGNPGGPNPAAQAARGGGGGAGEQQQQAGSGAPHTPQTPGQPGAPATPGTAGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTNGDPLNGHCYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSIQCS
What is the function of this protein?
Coup (chicken ovalbumin upstream promoter) transcription factor binds to the ovalbumin promoter and, in conjunction with another protein (S300-II) stimulates initiation of transcription.  Binds to both direct repeats and palindromes of the 5'-AGGTCA-3' motif.  Represses transcriptional activity of LHCG.
What are the official names of this protein?
COUP transcription factor 1, COUP-TF1, COUP transcription factor I, COUP-TF I, Nuclear receptor subfamily 2 group F member 1, V-erbA-related protein 3, EAR-3.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1794_HAEDU
Sequence: MFGNLQGKFIIATPEMDDEYFDRTVIYICEHNDNGTIGVIINTPTDLSVLELLTRMDFQMAKPRIYTQDQMVLNGGPVNQDRGFIVHSKTDHEFTHSYKVTDDITLTTSGDVLDSFGTQTAPEKFIVCLGCSTWKPHQLEQEIAQNYWLLSEANNQTLFETSYLDRWVEANEMLGISGILAPAGRA
What are the official names of this protein?
UPF0301 protein HD_1794.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: RL31B_BACTN
Sequence: MKKGLHPESYRPVVFKDMSNGDMFLSKSTVATKETIEFEGETYPLLKIEISNTSHPFYTGKSTLVDTAGRVDKFMSRYGDRKKK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: RL22_PSEPF
Sequence: MEVAAKLSGARISAQKARLVADQIRGKKVGEALNLLAFSSKKAAEIMKKVLESAVANAEHNEGADVDDLKVSTVFVNEGRSLKRIMPRAKGRADRIVKRSCHITVKVADK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: KDSB_FRAP2
Sequence: MVNIHVVIPARLKSTRLPGKMLADIAGKPMIQRVYEQVAKSKFKSIIIATDSQEIKEVAENFGAKVILTRDDHESGTDRIAEAVTKLGFADEDIVVNVQGDEPLIPVENIEQAAQLLIEKPEAVVSTLCERITEAEDIYNPNNVKVVFDKNNYALYFSRASIPFERGFSENHQVSISEFFRHIGIYTYRVGFLKHYAELAISPIEKYEALEQLRVLYNGYKIAIEQSAKPTPAGVDTLQDLEKVRKLFDV
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASIP_SEMEN
Sequence: MDVTRLLLATLLVFLCFFTVYSHLPPEEKLRDDRSLRSNSSVNLLDFPSVSIVALNKKSKQISRKEAEKKRSSKKEASMKKVAQPRTPLSAPCVATRYSCKPPAPACCDPCASCQCRFFRSACSCRVLRLNC
What is the function of this protein?
Involved in the regulation of melanogenesis.  The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).
What are the official names of this protein?
Agouti-signaling protein, ASP, Agouti switch protein.
What are the subcellular locations of this protein?
Secreted.
Protein: HSL16_DICDI
Sequence: MTLLASISSIGNVKSISKSNNFSSLSNSSLQSSNSIQCGGCGGGSPLIGTVGNLVGGVLVGTGIIVGTVVGTVNGVVGGLLSGPNCGCH
What are the official names of this protein?
HssA/B-like protein 16.
What is the protein family that this protein belongs to?
Belongs to the hssA/B family.
Protein: RIMP_LEVBA
Sequence: MSTVVETVTALAQPIVAQHQFELVDVEFVKEGKSWYLRLYIDKPGGINIEECALVSDEVSEKMDALDPDPIPQAYFLEVSSPGAERPLKKPADFEKAVGDYIHVSLYQKIGNSKVYEGTLLSLTADSLDLEVNLKGRIKTLTIPRDAVAQARLAIKF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ICA1L_HUMAN
Sequence: MDSFGQPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQETCTELLKIIEKYQLRLNVISEEENELGLFLKFQAERDATQAGKMMDATGKALCSSAKQRLALCTPLSRLKQEVATFSQRAVSDTLMTINRMEQARTEYRGALLWMKDVSQELDPDTLKQMEKFRKVQMQVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHSLTTYQRTLLGFWKKTARMMSQIHEACIGFHPYDFVALKQLQDTPSKISEDNKDEQIGGFLTEQLNKLVLSDEEASFESEQANKDHNEKHSQMREFGAPQFSNSENVAKDLPVDSLEGEDFEKEFSFLNNLLSSGSSSTSEFTQECQTAFGSPSASLTSQEPSMGSEPLAHSSRFLPSQLFDLGFHVAGAFNNWVSQEESELCLSHTDNQPVPSQSPKKLTRSPNNGNQDMSAWFNLFADLDPLSNPDAIGHSDDELLNA
What are the official names of this protein?
Islet cell autoantigen 1-like protein, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 14 protein, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 15 protein.