PharMolix/UniProtQA huggingface dataset:
Protein: Y2322_MYCBO
Sequence: MVATRGRPCPTNFSRPQRPRVAGNGTKSQRCRGRLTTSMLGVAPEAKGPPVKVHHLNCGTMNAFGIALLCHVLLVETDDGLVLVDTGFGIQDCLDPGRVGLFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAPSLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRHDPDLLIVCAHDPDLYQLARDTA
What are the official names of this protein?
Probable metallo-hydrolase Mb2322c.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
Protein: GLGC_THECA
Sequence: MVKVEVLGMILAGGQGSRLYPLTAKRAKPAVPFGAKYRIIDFVLNNFVNSGIYAIYVLTQYKAQSLTEHIQRYWRFGAFLEDHFILLVPAQMYRYEELGPVWYRGTADAIYQNLHLVHNHAPKAVAVFGGDHIFKMNIRHMVEYHYDTRADITIAAYPVPVAEATRFGVLQVDEEWRITEFQEKPEEPKPIPGRPDMALASMGNYIFRTEALFELLEADARDETSAHDFGKGVIPRAIRVGYRVYAYDFHRNPIPGQEGPNLYWRDVGTLDAYYEASMDLVKVDPVFGLCSPVWPLRTANLFSPPAKFVHETGERVGRALNSLLAGGVIVSGGTVRESVLFRRVRVNSYSLVERSVLFDDVEVGRYCRIRNAIIDKNVKIPPHTEIGYDLELDRARGFTVTPEGVVVVPKGYRF
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: P30_ASFE7
Sequence: MDFILNISMKMEVIFKTDLRSSSQVVFHAGSLYNWFSVEIINSGRIVTTAIKTLLSTVKYDIVKSAHIYAGQGYTEHQAQEEWNMILHVLFEEETESSASSESIHEKNDNETNECTSSFETLFEQEPSSEEPKDSKLYMLAQKTVQHIEQYGKAPDFNKVIRAHNFIQTIHGTPLKEEEKEVVRLMVIKLLKKK
What is the function of this protein?
Modifies the subcellular distribution of heterogeneous nuclear ribonucleoprotein K (HNRNPK) and may contribute to modulate HNRNPK functions related to processing and export of mRNAs during ASFV infection (By similarity).  Necessary for virus internalization (By similarity).
What are the official names of this protein?
Phosphoprotein p30, p32.
What is the protein family that this protein belongs to?
Belongs to the asfivirus phosphoprotein p30 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Virion.
Protein: LPRI_MYCTO
Sequence: MRWIGVLVTALVLSACAANPPANTTSPTAGQSLDCTKPATIVQQLVCHDRQLTSLDHRLSTAYQQALAHRRSAALEAAQSSWTMLRDACAQDTDPRTCVQEAYQTRLVQLAIADPATATPPVLTYRCPTQDGPLTAQFYNQFDPKTAVLNWKGDQVIVFVELSGSGARYGRQGIEYWEHQGEVRLDFHGATFVCRTS
What is the function of this protein?
Strongly binds and inhibits lysozyme, may help bacteria survive in lysozyme-producing host cells such as monocyte-derived macrophages.
What are the official names of this protein?
Lipoprotein LprI, Glycolipoprotein LprI, Lysozyme inhibitor LprI.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the MliC family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Secreted, cell wall. Cell surface.
Protein: HSPB1_CHICK
Sequence: MAERRVPFTFLTSPSWEPFRDWYHGSRLFDQSFGMPHIPEDWYKWPSGSAWPGYFRLLPSESALLPAPGSPYGRALSELSSGISEIRQSADSWKVTLDVNHFAPEELVVKTKDNIVEITGKHEEKQDEHGFISRCFTRKYTLPPGVEATAVRSSLSPDGMLTVEAPLPKPAIQSSEITIPVTVEAKKEEPAKK
What is the function of this protein?
Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state.  Plays a role in stress resistance and actin organization.
What are the official names of this protein?
Heat shock protein beta-1, HspB1, 25 kDa IAP, Actin polymerization inhibitor, Heat shock 25 kDa protein, HSP 25, Heat shock 27 kDa protein, HSP 27.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle.
Protein: RL6_METAC
Sequence: MVKEIARTIEIPEGVSVSLAQDVFTATGPKGTVERKLWYPGIMIDVKDGEVVVDAEYARKEQKAMVGTFASHIRNLVKGVNEGFECKMSIVYAHFPMQVKVDGKTLIIGNFLGEKKPRFAKIIGETKVKVSGNDVTITGINKEDVGQTAANIEQKTKIKRFDPRIFQDGIYIVQKA
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RL31_NITSB
Sequence: MRKDIHPEYVECEVTCACGNHFVVMSNKPQLKIDICNKCHPFFTGSEKIVDTTGRVDKFKKKYNLK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: SNAB_HUMAN
Sequence: MDNAGKEREAVQLMAEAEKRVKASHSFLRGLFGGNTRIEEACEMYTRAANMFKMAKNWSAAGNAFCQAAKLHMQLQSKHDSATSFVDAGNAYKKADPQEAINCLNAAIDIYTDMGRFTIAAKHHITIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAAYAAQLEQYQKAIEIYEQVGANTMDNPLLKYSAKDYFFKAALCHFIVDELNAKLALEKYEEMFPAFTDSRECKLLKKLLEAHEEQNSEAYTEAVKEFDSISRLDQWLTTMLLRIKKSIQGDGEGDGDLK
What is the function of this protein?
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.
What are the official names of this protein?
Beta-soluble NSF attachment protein, SNAP-beta, N-ethylmaleimide-sensitive factor attachment protein beta.
What is the protein family that this protein belongs to?
Belongs to the SNAP family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: RL31_IGNH4
Sequence: MPKEKDGVIYTINLRRLYWGRRSNRAKRAVRMVREFVARHFGVEPEDVKIDNTVNNYLWSGSITKPPARVQVYVTVKTESGEEGERKVAYVTLANVKDVED
What are the official names of this protein?
50S ribosomal protein L31e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: CDA1_ARATH
Sequence: MDKPSFVIQSKEAESAAKQLGVSVIQLLPSLVKPAQSYARTPISKFNVAVVGLGSSGRIFLGVNVEFPNLPLHHSIHAEQFLVTNLTLNGERHLNFFAVSAAPCGHCRQFLQEIRDAPEIKILITDPNNSADSDSAADSDGFLRLGSFLPHRFGPDDLLGKDHPLLLESHDNHLKISDLDSICNGNTDSSADLKQTALAAANRSYAPYSLCPSGVSLVDCDGKVYRGWYMESAAYNPSMGPVQAALVDYVANGGGGGYERIVGAVLVEKEDAVVRQEHTARLLLETISPKCEFKVFHCYEA
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.  Functions as a conventional cytidine deaminase.  Has no affinity for RNA and is not involved in RNA-editing by C-to-U deamination.
What are the official names of this protein?
Cytidine deaminase 1, At-CDA1.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: Y5346_VIBC1
Sequence: MSSVFEIVNQARRKNKLKRELLDNEKKVRDNRKRVDLLENLLDYIKPEMTHDEIVAIIKNMKADYEDRVDDHIIKSAEISKARRDISRRIRELTEEDKQTSGKK
What are the official names of this protein?
UPF0265 protein VIBHAR_05346.
What is the protein family that this protein belongs to?
Belongs to the UPF0265 family.
Protein: RL6_STRE4
Sequence: MSRIGNKVIIIPAGVEIINNDNVVTVKGPKGELTREFNKNIEIKVEGNEMTLVRPDDSKEMKTIHGTTRANLNNMVVGVSEGFKKELEMKGVGYRAQLQGSKLVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGKGIRYVGEYVRLKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: HTF_LOBDE
Sequence: QVNFSPGWGT
What is the function of this protein?
Hypertrehalosaemic factors are neuropeptides that elevate the level of trehalose in the hemolymph (trehalose is the major carbohydrate in the hemolymph of insects).
What are the official names of this protein?
Hypertrehalosaemic factor, Adipokinetic hormone 1, LobDe-AKH-1, Hypertrehalosaemic neuropeptide.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: HBB2_XENLA
Sequence: MVHWTAEEKAAITSVWQKVNVEHDGHDALGRLLIVYPWTQRYFSNFGNLSNSAAVAGNAKVQAHGKKVLSAVGNAISHIDSVKSSLQQLSKIHATELFVDPENFKRFGGVLVIVLGAKLGTAFTPKVQAAWEKFIAVLVDGLSQGYN
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta-2, Beta-2-globin, B2G, Hemoglobin beta-2 chain, Hemoglobin beta-minor chain, Larval beta-II-globin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: Y1653_THESQ
Sequence: MKVTFLGHAVVLIEGKKNIIIDPFISGNPVCPVKLEDLPKIDYILVTHGHGDHLGDAVEIAKKNDATVISNYEICHYLGKKGVKTHAMHIGGSYLFDFGRVKMTPAVHGSGILDGDSMIYGGNPSGFLITIEGKKIYHAGDTGLTREMELLAEENVDVAFLPIGGNFVMDVEDAVRAAVMIKPKKVVPMHYGTWELIFADVELFKKKVEEKGVECVILEPGESLEL
What are the official names of this protein?
UPF0173 metal-dependent hydrolase TRQ2_1653.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: Y220_MYCGE
Sequence: MYKLEKAQAKQVVGGLSFWTFSAGLIMIVNALTGVAHAVNDIFQSTTANANGSDDDNENKNNSYRSKSNYFNTARFKLGLTPGSSSYSFPVFS
What are the official names of this protein?
Uncharacterized protein MG220.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: Y3395_MYCTO
Sequence: MTAAFASDQRLENGAEQLESLRRQMALLSEKVSGGPSRSGDLVPAGPVSLPPGTVGVLSGARSLLLSMVASVTAAGGNAAIVGQPDIGLLAAVEMGADLSRLAVIPDPGTDPVEVAAVLIDGMDLVVLGLGGRRVTRARARAVVARARQKGCTLLVTDGDWQGVSTRLAARVCGYEITPALRGVPTPGLGRISGVRLQINGRGR
What are the official names of this protein?
Uncharacterized protein MT3502.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CSF1_MOUSE
Sequence: MTARGAAGRCPSSTWLGSRLLLVCLLMSRSIAKEVSEHCSHMIGNGHLKVLQQLIDSQMETSCQIAFEFVDQEQLDDPVCYLKKAFFLVQDIIDETMRFKDNTPNANATERLQELSNNLNSCFTKDYEEQNKACVRTFHETPLQLLEKIKNFFNETKNLLEKDWNIFTKNCNNSFAKCSSRDVVTKPDCNCLYPKATPSSDPASASPHQPPAPSMAPLAGLAWDDSQRTEGSSLLPSELPLRIEDPGSAKQRPPRSTCQTLESTEQPNHGDRLTEDSQPHPSAGGPVPGVEDILESSLGTNWVLEEASGEASEGFLTQEAKFSPSTPVGGSIQAETDRPRALSASPFPKSTEDQKPVDITDRPLTEVNPMRPIGQTQNNTPEKTDGTSTLREDHQEPGSPHIATPNPQRVSNSATPVAQLLLPKSHSWGIVLPLGELEGKRSTRDRRSPAELEGGSASEGAARPVARFNSIPLTDTGHVEQHEGSSDPQIPESVFHLLVPGIILVLLTVGGLLFYKWKWRSHRDPQTLDSSVGRPEDSSLTQDEDRQVELPV
What is the function of this protein?
Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes.  Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes.  Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development.  Required for normal male and female fertility.  Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration.  Plays a role in lipoprotein clearance.
What are the official names of this protein?
Macrophage colony-stimulating factor 1, CSF-1, MCSF, Proteoglycan macrophage colony-stimulating factor, PG-M-CSF.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Processed macrophage colony-stimulating factor 1]: Secreted, extracellular space.
Protein: CQ078_MOUSE
Sequence: MDTILVFSLMIASYDSNKNDLRKSSCQVEQWPSFFSEDVRSNKDLVVRVPLEIHTDTKGTPFIQNQPIATLRCLGSGRRVTVHLVYSERRPKVKYIMKNLPVITDLPRNSTASPRCHLRATSQFQNGSLLTAFLPGISQCTVYSAKDRSASSEMVPITTSSTTPRSKGDEATSTGAFPNPLTQGIDMSLKRRQKWSLVVKALIAVTLLLGGAAIIVFVIFEVPCPSQCLRVRQLCQCQWLWRRKRKEEDQKPGTTESQLDSQPEKVKHNVPNSSDSKKTTDIAIIYQTYF
What are the official names of this protein?
Uncharacterized protein C17orf78 homolog.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CAD16_RABIT
Sequence: MVPAWLWLLCFSVPQALVEVSPTTLHVEVPENYGGNFPLYLTKLPWPHKEAGGRVVLSGDSGVAAEGPFSVEAESGFLLVTRALDREEQAEYQIQVTLEAEDGHVLWGPQSVTVHVKDENDQVPQFSQALYSARLSQGTRPGVPFLFLEASDGDEPGTANSDLRFHILSQTPAQPSPDVFRLEPRLGALALSPEGSAGFDHALEGPYQLLVQVKDMGDQASGHQATATVEISIVESTWTPLEPVHLAENLKVPYPHHLAQVHWSGGDVHYRLESQPPGPFDVDTEGKLYVTGELDREAQEQYVLQVQAQNSRGEDYAEPLELHVVVTDENDHAPVCPPRGPPVSVPELSPPGTAVTTLSAEDADAPGSPNSHVVYRLLSPEPQEGPEGGAFQLDPTSGSVSLGAAPLEAGQNMLLQVLAVDLAGAEAGLSSTCEVAVTVTDVNDHAPEFTSSQVGPVSLPEDTEPGTLVATLTATDADLEPAFRLMDFTIEAGDGEGTFGLDWEPDSGHVQLYLLKNLSYEAAPSHTVVVVVRNVVETVGPGPGPGATATVTVLVEKVMPPPRLEQKSYEADIPVNAPAGSFLLTIQPAEPWNGALRFSLVNDSEGWFCIQKVSGEVHTARPLQGARPGDSYTVLVEAQDADAPRLSTSAALVIHFLRAPPAPALPLAPMPSRHLCTPRQDHGVLIPAPSEDPDMATGHGPYSFALGPNPTVQRDWRLQPLNDSHAFLTLALHWVEPREHIVPVVVSQDARVWQLPVRVVVCRCNTEGECMRKVGRMKGMPTKLSAVGILVGTLAAIGFFLILIFTHLALARKKDLDAPADNVPLKAAA
What is the function of this protein?
Cadherins are calcium-dependent cell adhesion proteins.  They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
What are the official names of this protein?
Cadherin-16, Kidney-specific cadherin, Ksp-cadherin.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: IFNG_MACMU
Sequence: MKYTSYILAFQLCIVLGSLGCYCQDPYVKEAENLKKYFNAGDPDVADNGTLFLDILRNWKEESDRKIMQSQIVSFYFKLFKNFKDDQRIQKSVETIKEDINVKFFNSNKKKRDDFEKLTNYSVTDSNVQRKAVHELIQVMAELSPAAKIGKRKRSQMFRGRRASQ
What is the function of this protein?
Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation.  Primarily signals through the JAK-STAT pathway after interaction with its receptor IFNGR1 to affect gene regulation.  Upon IFNG binding, IFNGR1 intracellular domain opens out to allow association of downstream signaling components JAK2, JAK1 and STAT1, leading to STAT1 activation, nuclear translocation and transcription of IFNG-regulated genes.  Many of the induced genes are transcription factors such as IRF1 that are able to further drive regulation of a next wave of transcription.  Plays a role in class I antigen presentation pathway by inducing a replacement of catalytic proteasome subunits with immunoproteasome subunits.  In turn, increases the quantity, quality, and repertoire of peptides for class I MHC loading.  Increases the efficiency of peptide generation also by inducing the expression of activator PA28 that associates with the proteasome and alters its proteolytic cleavage preference.  Up-regulates as well MHC II complexes on the cell surface by promoting expression of several key molecules such as cathepsins B/CTSB, H/CTSH, and L/CTSL (By similarity).  Participates in the regulation of hematopoietic stem cells during development and under homeostatic conditions by affecting their development, quiescence, and differentiation (By similarity).
What are the official names of this protein?
Interferon gamma, IFN-gamma.
What is the protein family that this protein belongs to?
Belongs to the type II (or gamma) interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: YQGF_METCA
Sequence: MAEVPADSRGATYLGFDFGERNIGVAVGQSVTGTAAPLRTLRAQPSARLWAAISELIDQWLPAGLVVGLSHQQDGSENPITAPTLRFCRQLEGRYRLPVYTVDETLTTAESRTHFYQRRRRKSVEFEQVKDEMAAQLILQTWFSIDKASPR
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2GD_HUMAN
Sequence: MELALLCGLVVMAGVIPIQGGILNLNKMVKQVTGKMPILSYWPYGCHCGLGGRGQPKDATDWCCQTHDCCYDHLKTQGCSIYKDYYRYNFSQGNIHCSDKGSWCEQQLCACDKEVAFCLKRNLDTYQKRLRFYWRPHCRGQTPGC
What is the function of this protein?
Secretory calcium-dependent phospholipase A2 that primarily targets extracellular lipids, exerting anti-inflammatory and immunosuppressive functions (PubMed:10455175, PubMed:10681567).  Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity) with preference for phosphatidylethanolamines and phosphatidylglycerols over phosphatidylcholines (PubMed:10455175).  In draining lymph nodes, selectively hydrolyzes diacyl and alkenyl forms of phosphatidylethanolamines, releasing omega-3 polyunsaturated fatty acids (PUFAs) such as eicosapentaenoate and docosahexaenoate that are precursors of the anti-inflammatory lipid mediators, resolvins (By similarity).  During the resolution phase of acute inflammation drives docosahexaenoate-derived resolvin D1 synthesis, which suppresses dendritic cell activation and T-helper 1 immune response (By similarity).  May act in an autocrine and paracrine manner (By similarity).  Via a mechanism independent of its catalytic activity, promotes differentiation of regulatory T cells (Tregs) and participates in the maintenance of immune tolerance (By similarity).  May contribute to lipid remodeling of cellular membranes and generation of lipid mediators involved in pathogen clearance.  Displays bactericidal activity against Gram-positive bacteria by directly hydrolyzing phospholipids of the bacterial membrane (By similarity).
What are the official names of this protein?
Group IID secretory phospholipase A2, GIID sPLA2, sPLA2-IID, PLA2IID, Phosphatidylcholine 2-acylhydrolase 2D, Secretory-type PLA, stroma-associated homolog.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: IHFA_RHOCA
Sequence: MSEKTLTRMDLSEAVFREVGLSRNESAQLVETVLQHMSDALVRGETVKISSFGTFSVRDKTSRMGRNPKTGEEVPISPRRVLSFRPSHLMKDRVAERNAK
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.  Involved in hydrogenase gene expression.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: AT1A1_PONAB
Sequence: MAFKVGRDKYEPAAVSEQGDKKGKKGKKDRDMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEAGTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPRHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISTAYGQIGMIQALGGFFTYFVILAENGFLPLHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY
What is the function of this protein?
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane.  This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit alpha-1, Na(+)/K(+) ATPase alpha-1 subunit, Sodium pump subunit alpha-1.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein. Cell membrane, sarcolemma; Multi-pass membrane protein. Cell projection, axon. Melanosome.
Protein: GAG_HV1MP
Sequence: MGARASVLSGGKLDAWEKIRLKPGGKKRYRLKHLVWASRELERFALNPSLLETTEGCKKIIGQLQSSLQTGSEELKSLYNAVVVLYYVHQRIDVRDTKEALDKLQEEQDKSQQKEQQKAADKEVSQNYPIVQNIQGQMVHQALSPRTLNAWVKVIEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKDTINEEAAEWDRLHPVHAGPIPPGQMREPRGSDIAGTTSTLQEQITWMTGNPPVPVGEIYKRWIILGLNKIVRMYSPVSILDIKQGPKEPFRDYVDRFFKTLRAEQATQEVKNWMTETLLVQNSNPDCKTILKALGPGATLEEMMTACQGVGGPGHKARILAEAMSKATSTAIMMQKSNFKGQKRIVKCFNCGKEGHIARNCRAPRKKGCWKCGKEGHQMKDCTERQANFLGKIWPSNRGRPGNFLQNRPEPTAPPAENFGFGEGITPSPKQEQKGEEQAPPLVSLKSLFGSDP
What is the function of this protein?
Plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1.
What are the official names of this protein?
Gag polyprotein, Pr55Gag.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group gag polyprotein family.
What are the subcellular locations of this protein?
[Gag polyprotein]: Host cell membrane; Lipid-anchor. Host endosome, host multivesicular body. Note=These locations are probably linked to virus assembly sites. The main location is the cell membrane, but under some circumstances, late endosomal compartments can serve as productive sites for virion assembly. SUBCELLULAR LOCATION: [Matrix protein p17]: Virion membrane; Lipid-anchor. Host nucleus. Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p7]: Virion.
Protein: LIFO_ACIVR
Sequence: MSGKFINHKTIVFGVITSVLLLLLLIYYVFKPEAQTQNQNINTQTIQPENTVLESATANNKQGKLPTLAASLQGTEIDCPIQVDANGKLILTVGIRSCFDYFFSSLGEKTEAELVADIRQYLLATLPESASNYAIYLLDQYVAYMHALQNLKPNAGFKSNNVDALQKVVDQMAKVQQQFFNAAEINALFGNERNLNQFNLEQMRIHANKNLTTQEKATELAKLIDELPPALADGVRVSMQFAELQQLTKEIQAKGGSAQDLRSMRESLLGPEAADRLEKVDQEEAVWQTQVNQYLSARDQILKSDANDASKQQSIAELRNSSFGTKEDLLRAQSYEVMHDQKSKGS
What is the function of this protein?
May be involved in the folding of the extracellular lipase during its passage through the periplasm.
What are the official names of this protein?
Lipase chaperone, Lipase activator protein, Lipase foldase, Lipase helper protein, Lipase modulator.
What is the protein family that this protein belongs to?
Belongs to the lipase chaperone family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Periplasmic side.
Protein: COBS_NOSS1
Sequence: MVKLLLLNLLASIIFYTNIPLPYINGLDFQRVARLVPTVGLIIGGILGLFDGGMNYLGMPVLTRSALVVVLWIFITGGLHLDGAMDTADGLAVGDPERRLEVMADSATGAFGAMSAIAILLLKTSALTEIGEYRWLVLMAACGWGRWGQQVAIACYPYLKATGKGAFHKQAIRSYKDLLPGLCLMFAISGLFWLVNNHHLLISVVVLIAGSAIATLTAAWFNHKLGGHTGDTYGAVVEWTEALFLCVLTILT
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.