PharMolix/UniProtQA huggingface dataset:
Protein: RIR2_VZVD
Sequence: MDQKDCSHFFYRPECPDINNLRALSISNRWLESDFIIEDDYQYLDCLTEDELIFYRFIFTFLSAADDLVNVNLGSLTQLFSQKDIHHYYIEQECIEVVHARVYSQIQLMLFRGDESLRVQYVNVTINNPSIQQKVQWLEEKVRDNPSVAEKYILMILIEGIFFVSSFAAIAYLRNNGLFVVTCQFNDLISRDEAIHTSASCCIYNNYVPEKPAITRIHQLFSEAVEIECAFLKSHAPKTRLVNVDAITQYVKFSADRLLSAINVPKLFNTPPPDSDFPLAFMIADKNTNFFERHSTSYAGTVINDL
What is the function of this protein?
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis.  Allows virus growth in non-dividing cells, as well as reactivation from latency in infected hosts.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase small subunit, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: HIP1_MYCBO
Sequence: MGMRLSRRDKIARMLLIWAALAAVALVLVGCIRVVGGRARMAEPKLGQPVEWTPCRSSNPQVKIPGGALCGKLAVPVDYDRPDGDVAALALIRFPATGDKIGSLVINPGGPGESGIEAALGVFQTLPKRVHERFDLVGFDPRGVASSRPAIWCNSDADNDRLRAEPQVDYSREGVAHIENETKQFVGRCVDKMGKNFLAHVGTVNVAKDLDAIRAALGDDKLTYLGYSYGTRIGSAYAEEFPQRVRAMILDGAVDPNADPIEAELRQAKGFQDAFNNYAADCAKNAGCPLGADPAKAVEVYHSLVDPLVDPDNPRISRPARTKDPRGLSYSDAIVGTIMALYSPNLWQHLTDGLSELVDNRGDTLLALADMYMRRDSHGRYNNSGDARVAINCVDQPPVTDRDKVIDEDRRAREIAPFMSYGKFTGDAPLGTCAFWPVPPTSQPHAVSAPGLVPTVVVSTTHDPATPYKAGVDLANQLRGSLLTFDGTQHTVVFQGDSCIDEYVTAYLIGGTTPPSGAKC
What is the function of this protein?
Key immunomodulatory virulence factor, which promotes survival in host macrophages and modulates host immune responses.
What are the official names of this protein?
Serine protease Hip1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S33 family.
What are the subcellular locations of this protein?
Cell envelope. Cell membrane; Lipid-anchor.
Protein: PSIE_PECCP
Sequence: MAGSARSAMAAKALQTILNIGLLVLATILVIFLVKETFHLAKVLLISNEKDSSYQLIEGIVIYFLYFEFIALIVKYFQSGYHFPLRYFIYIGITAIIRLIIVDHKSPSDTLMYSAAILLLVVTLYLANSNRLKRE
What are the official names of this protein?
Protein PsiE homolog.
What is the protein family that this protein belongs to?
Belongs to the PsiE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ILVD_FRAP2
Sequence: MTKVLNKYSRRLTEDKSQGASQAMLYGTGMNDNDMHKPQIGIASVWYEGNTCNMHLNQLAQFVKNSVEKENLKGMRFNTIGVSDGISMGTDGMSYSLQSRDLIADSIETVMSAHWYDGLVSIPGCDKNMPGCMMALGRLNRPGFVIYGGTIQAGVMRGKPIDIVTAFQSYGACLSGQISEQERQETIKKACPGAGACGGMYTANTMACAIEALGMSLPFSSSTPATSVEKVQECDKAGETIKNLLELDIKPRDIMTRKAFENAMVLITVMGGSTNAVLHLLAMASSVDVDLNIDDFQEIANKTPVLADFKPSGKYVMADLHAIGGTPAVMKMLLKAGMLHGDCLTVTGKTLAENLESVADLPEDNTIIHKLDNPIKKTGHLQILKGNVAPEGSVAKITGKEGEVFEGVANVFDSEEEMVAAVEEGKVKKGDVIVIRYEGPKGGPGMPEMLKPTSLIMGAGLGQDVALITDGRFSGGSHGFIVGHIAPEAYEGGMLALLENGDKITIDAINNVINVDLSDQEIAQRKAKWQAPKQKATRGTLKKYIKTVSSASTGCVTDLD
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: HIS7_CAMJR
Sequence: MSQKILFIDRDGTLIEEPKSDFQIDTLEKLRFEKDAIPTLLKLKKFGFKFVMVSNQDGLGTPSFPKENFEIAHEKMLDILKSCGIEFQDIFICPHFENENCVCRKPKTAMLEEYIKHELYDKEQSFVIGDRESDMILASNLGVRGLKYGELSWKEIENEILSSFRSASYQRTTKETDIKVKVCLNGGKVSIKTGIDFFDHMLEQIAVHGGIGLEISCKGDLEIDEHHSVEDVALALGACIKKTLGDKIGIARYGFALPMDECLASCAMDFCNRPHLVYKAKFKKSHLGALSTEMIEHFFYSLSYAMGVSLHLKVKGKNDHHKAEGLFKAFAKALKMAVKIESENLASSKGVI
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisB.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TXG3A_SCOMO
Sequence: MALPSTLSSIVLRWVLFAIFLLLVEAGERQYRTESRDGKCVGEDGQVHAVTEIWYNDNDCSEHTCVNDHTGYYEIIRRCTLIVYPPECRLVNGTGTRYPKCCCGVTCELN
What are the official names of this protein?
U-scoloptoxin(16)-Sm3a, U-SLPTX(16)-Sm3a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-16 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PURP_THEKO
Sequence: MRVATYASHSALQILKGAKDEGFETVAFGPSRVKPLYTKYFPVADHFIEGAYPEEELLEFEAVVVPTGSFVAHLGVELVEKMKVPYYGNKAVLRWESDRSLERKWLEKAKLRLPRIYEDPDDIDGPVIVKPFGAGGGRGYFLASSPEDFWKKAERLGVRSKEDLSRVQIQEYVVGVPVYPHYFYSKLNGELELMSVDRRYESNADAIGRIPAREQIDLGISTDYTVVGNIPIVLRESLLMDVIEAGERVVKAAEELMGGLWGPFCLEGVFTPDMEFVVFEISARIVAGTNPFVHGSPYTWLRYDFPVSTGRRIAMELKQGLEEDRLGELLT
What is the function of this protein?
Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.
What are the official names of this protein?
5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase, 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate--formate ligase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: GLK_ERWT9
Sequence: MTKYALVGDVGGTNARLALCEIDNGAISQAKTFSTADYDSLEAVIRAYLAEKQQDIKHGCIAIACPITDDWVEMTNHDWAFSTSSMKANLAFDSLEIINDFTAVSMAIPMLSEEHLMQFGGTTPAEDKPVAVYGAGTGLGVAHLVHVDKRWVSLPGEGGHVDFAANSEEEDLILEVLREELGHVSAERILSGNGLVNLYRAIVKSDHRQPEDLKPRDVTERALQDTCTDCRRALSMFCVIMGRFGGNLALNLGTFGGVYIAGGIVPRFLEFFKASGFRAAFEDKGRFKDYVAPIPVYLITHDYPGLLGSGAHLRQTLGRVL
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPL_GLOAU
Sequence: MKFFAVFALCVASVSAANLDAIAKPGFPAGRIINGHEAEKGEAPFIVSLKAGKGHFCGGSIIAENWVLTAGHCLIFDEFEIVAGLHSRNDESDVQIRKVTGKHQQIVHEKYGGGVGPNDIGLIYVDKPFNLNALTRDGTAAVAKVNLPTGKYESTGEGKLYGWGLDNSGFSPNILNTLDVNIIGYEECKNALNSDAPLDPVNICSYTAGAIDGACNGDSGGPMVRITPDGTELVGIVSWGYQPCASTTMPSVYTWTSAFDKWIEDSIENYAQLL
What is the function of this protein?
Protein with lectin and protease activity involved in the establishment of trypanosome infections in tsetse flies.  Binds D-glucosamine and agglutinates bloodstream-form trypanosomes and rabbit red blood cells.  Capable of inducing transformation of bloodstream-form trypanosomes into procyclic (midgut) forms in vitro.
What are the official names of this protein?
Lectizyme, Proteolytic lectin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: GREA_STAA9
Sequence: MENQKQYPMTQEGFEKLERELEELKTVKRPEVVEKIKVARSFGDLSENSEYDAAKDEQGFIEQDIQRIEHMLRNALIIEDTGDNNVVKIGKTVTFVELPGDEEESYQIVGSAESDAFNGKISNESPMAKALIGKGLDDEVRVPLPNGGEMNVKIVNIQ
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: ASNS_HUMAN
Sequence: MCGIWALFGSDDCLSVQCLSAMKIAHRGPDAFRFENVNGYTNCCFGFHRLAVVDPLFGMQPIRVKKYPYLWLCYNGEIYNHKKMQQHFEFEYQTKVDGEIILHLYDKGGIEQTICMLDGVFAFVLLDTANKKVFLGRDTYGVRPLFKAMTEDGFLAVCSEAKGLVTLKHSATPFLKVEPFLPGHYEVLDLKPNGKVASVEMVKYHHCRDVPLHALYDNVEKLFPGFEIETVKNNLRILFNNAVKKRLMTDRRIGCLLSGGLDSSLVAATLLKQLKEAQVQYPLQTFAIGMEDSPDLLAARKVADHIGSEHYEVLFNSEEGIQALDEVIFSLETYDITTVRASVGMYLISKYIRKNTDSVVIFSGEGSDELTQGYIYFHKAPSPEKAEEESERLLRELYLFDVLRADRTTAAHGLELRVPFLDHRFSSYYLSLPPEMRIPKNGIEKHLLRETFEDSNLIPKEILWRPKEAFSDGITSVKNSWFKILQEYVEHQVDDAMMANAAQKFPFNTPKTKEGYYYRQVFERHYPGRADWLSHYWMPKWINATDPSARTLTHYKSAVKA
What are the official names of this protein?
Asparagine synthetase [glutamine-hydrolyzing], Cell cycle control protein TS11, Glutamine-dependent asparagine synthetase.
Protein: SBCD_STAAS
Sequence: MKIIHTADWHLGKILNGKQLLEDQAYILDMFVEKMKEEEPDIIVIAGDLYDTTYPSKDAIMLLEQAIGKLNLELRIPIIIISGNHDGKERLNYGASWFEHNQLFIRTDFTSINSPIEINGVNFYTLPYATVSEMKHYFEDDTIETHQQGITRCIETIAPEIDEDAVNILISHLTVQGGKTSDSERPLTIGTVESVQKGVFDIFDYVMLGHLHHPFSIEDDKIKYSGSLLQYSFSEAGQAKGYRRVTINDGIINDVFIPLKPLRQLEIISGEYNDVINEKVHVKNKDNYLHFKLKNMSHITDPMMSLKQIYPNTLALTNETFNYNEENNAIEISEKDDMSIIEMFYKHITDKELSDIQSKKIKNILENELRKED
What is the function of this protein?
SbcCD cleaves DNA hairpin structures.  These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions.  The complex acts as a 3'->5' double strand exonuclease that can open hairpins.  It also has a 5' single-strand endonuclease activity (By similarity).
What are the official names of this protein?
Nuclease SbcCD subunit D.
What is the protein family that this protein belongs to?
Belongs to the SbcD family.
Protein: MSUD_PSEAE
Sequence: MNVFWFLPTHGDGHFLGTSQGARPVSLPYLKQVAQAADSLGYHGVLIPTGRSCEDSWVVASALAPLTERLRFLVAIRPGIVSPTVSARMAATLDRLSGGRLLINVVTGGDPDENRGDGIHLGHAERYEVTDEFLRVWRRVLQGEAVDFHGKHIHVENAKALYPPLQRPYPPLYFGGSSEAAHELAGEQVDVYLTWGEPLPAVAAKIADVRQRAARHGRTVKFGIRLHVIVRETAEEAWRAADRLIEHISDETIAAAQQSFARFDSEGQRRMAALHGGRRDRLEIQPNLWAGVGLVRGGAGTALVGDPRQVAERIGEYAELGIDSFIFSGYPHLEEAYRFAELVFPLLPEPYASLAGRGLTNLTGPFGEMIANDVLPARAGA
What is the function of this protein?
Catalyzes the desulfonation of aliphatic sulfonates.  Shows highest activity with methanesulfonate.
What are the official names of this protein?
Methanesulfonate monooxygenase, FMNH2-dependent methanesulfonate monooxygenase, Methanesulfonate sulfonatase.
What is the protein family that this protein belongs to?
Belongs to the SsuD family.
Protein: FABZ_SYNJA
Sequence: MSSDVSPPPLLSAEAAAQLATAPPVFTTDQILEILPHRYPFLLVDRVVEYQPGQRAVGLKNVTFNEPFFQGHFPNRPIMPGVLIVEAMAQLGGIVLTKLPDVAGRLALFAGIDGVRFRRPVLPGDQLLLSANLLTIRQKRIGKMFCRAQVGGQLVTEGELMFSLVD
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFBE_METBF
Sequence: MDLYRKKFAVLDLTHGGIPIAKSLAAAGNEVSGIDVYRTVKPETLLELEEKYGIHCSKTPLPASGFDLIVAPVHLDPAYPMLLEARAQKKKVLSHHEIVGEILKGDSRLSSIKTVEVTGVKAKTSTASLLADMLSRQFEVVLHTSRGLECWKAGASSLIYKGLSITPGSILVAVEKTFEAGFRPDFFIFEISIGGTGTADLGILTTLSPDYGIANNTALASEAKLQLIKHAKSGSTLLINAGAEKALKAAKKDQVKVLTFRDPFNDQLSATSVQIADFVLETVPETSALSVPSELVMPSGLQKPAGLSGSSEPDSLSGSSTSAGLSDSSMPAGSTEFQASPTPSGSDIRFMRRGKKILSASLRPGYNVSAYRTAFVAASAAAIELGTKPEAIISAIEGFRGLSGRMQEKEMNGVSLIDNSNSGMDILSAEKALDYALLKRKDEKKEGIILVLGEESSQVCEGLPPELVQGFIEKFGAKCKQVILVGERMKAVNGKNISYARDLTEGLSKASEFAGGDDIILSSVKCFR
What is the function of this protein?
Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation.  Catalyzes the activation the g-propionate side chain of 15,17(3)-seco-F430-17(3)-acid (seco-F430) for intramolecular C-C bond formation to yield the carbocyclic F ring of coenzyme F430.
What are the official names of this protein?
Coenzyme F(430) synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
Protein: ARRD_RAT
Sequence: LKHEDTNLSVSLTDSSVVSLYSGTVLFKSMHTLPTNARCPNLSVISATSGMSQCELSQSSMPWWCRSLVFS
What are the official names of this protein?
Arrestin-D.
What is the protein family that this protein belongs to?
Belongs to the arrestin family.
Protein: MOAC_SHEB5
Sequence: MSNVFTHINADGNAHMVDVTEKAVTEREARAEAFIEMASTTLEMIMSGSHHKGDVFATARIAGIQAAKKTSDLIPLCHPLMLTKVEVDLEAQPEHNRVRITSLCKLSGKTGVEMEALTAASVAALTIYDMCKAVQKDMVISQVRLLEKRGGKSGHFKV
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: PA2_NOTSC
Sequence: NLIQLSNMIKCAIPGSQPLF
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that exhibits weak enzymatic activity.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Phospholipase A2 II-5b, svPLA2, Notechis II-5b non-toxic venom protein, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CSRA_DICNV
Sequence: MLILTRRVGETIIIDDQIKVTVLAVKGNQVRLGVQAPDEIAIHREEIYHRLMNGVGDDAEMEKK
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHNC_STAAC
Sequence: MSQIEFKNVSKVYPNGHVGLKNINLNIEKGEFAVIVGLSGAGKSTLLRSVNRLHDITSGEIFIQGKSITKAHGKALLEMRRNIGMIFQHFNLVKRSSVLRNVLSGRVGYHPTWKMVLGLFPKEDKIKAMDALERVNILDKYNQRSDELSGGQQQRISIARALCQESEIILADEPVASLDPLTTKQVMDDLRKINQELGITILINLHFVDLAKEYGTRIIGLRDGEVVYDGPASEATDDVFSEIYGRTIKEDEKLGVN
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SYT_BURVG
Sequence: MVSIRLPDGSVRQYEHPVTVAEVAASIGPGLAKAALGGKLDGELVDTSTVIDRDASLAIVTDKDADGLDIIRHSTAHLLAYAVKELYPEAQVTIGPVIDNGFYYDFAYNRPFTPEDLEKIEKRMQELAKKDEPVTRRVVSRDEAAGYFRSIGEKYKAEIIESIPQSDEIKLYSHGGFTDLCRGPHVPSTGKLKVFKLMKVAGAYWRGDSKNEQLQRIYGTAWTKKEDQDQYLHMLEEAEKRDHRKLGKQLDLFHMQEESPGMVFWHPKGWALWQQVEQYMRRRVNDAGYLEIKTPMIMDRSLWEASGHWQNYRENMFTTESEKRDYAIKPMNCPGHVQVFKHGLRSYRDLPLRYAEFGSCHRNEASGALHGLMRVRGFVQDDAHIFCTEDQFIAESIAFNTLAMSVYKDFGFEHIDIKLSLRPEQRAGTDETWDRAEQGLRDALTACGLTWQELPGEGAFYGPKIEYHIKDALGRSWQCGTLQLDMVLPERLGAEYVAEDNSRRRPVMLHRAIVGSMERFLGILIEHHAGAMPVWLAPFQAIVLNIAESQAEYAQSLAQTLQKQGVRVAADLRNEKISYKIREHTLEKVPYLLVVGDKERDAQTVAVRARGGVDLGVMPVEAFVERLQEDLRSFK
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CE85L_HUMAN
Sequence: MWGRFLAPEASGRDSPGGARSFPAGPDYSSAWLPANESLWQATTVPSNHRNNHIRRHSIASDSGDTGIGTSCSDSVEDHSTSSGTLSFKPSQSLITLPTAHVMPSNSSASISKLRESLTPDGSKWSTSLMQTLGNHSRGEQDSSLDMKDFRPLRKWSSLSKLTAPDNCGQGGTVCREESRNGLEKIGKAKALTSQLRTIGPSCLHDSMEMLRLEDKEINKKRSSTLDCKYKFESCSKEDFRASSSTLRRQPVDMTYSALPESKPIMTSSEAFEPPKYLMLGQQAVGGVPIQPSVRTQMWLTEQLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKWESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQTVLSKRPLFDLTVIDQLFKEMSCCLFDLKALCSILNQRAQGKEPNLSLLLGIRSMNCSAEETENDHSTETLTKKLSDVCQLRRDIDELRTTISDRYAQDMGDNCITQ
What is the function of this protein?
Plays an essential role in neuronal cell migration.
What are the official names of this protein?
Centrosomal protein of 85 kDa-like, Serologically defined breast cancer antigen NY-BR-15.
What is the protein family that this protein belongs to?
Belongs to the CEP85 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localized specifically to the pericentriolar region.
Protein: DNAJ_STAA2
Sequence: MAKRDYYEVLGISKDASKDEIKKAYRKLSKKYHPDINKEEGADEKFKEISEAYEVLSDDNKRASYDQFGHDGPQGFGGQGFNGSDFGGFSGFGGGGFEDIFSSFFGGGRQRDPNAPQKGDDLQYTMTLTFEEAVFGTTKEISIRKDVTCETCHGDGAKPGTSKKTCSYCNGAGHVAVEQNTILGRVRTEQVCPKCNGSGQEFEEACPTCHGKGTENKTVKLEVKVPEGVDNEQQIRLAGEGSPGVNGGPAGDLYVVFRVKPSETFKRDGDDIYYKLNVSFPQAALGDEIKIPTLNNEVMLTIPAGTQTGKQFRLKEKGIKNVHGYGYGDLYVDIKVVTPTKLTDRQKELMKEFAQLNGEEINEQPSNFKDRAKRFFKGE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBL5_DICDI
Sequence: MIEVVCNDRLGNKVRVKVNSDDTIGDLKKVLSAQIGIKAEKIRLQKSYSIFKDHEIHDGDGLELYYN
What are the official names of this protein?
Ubiquitin-like protein 5.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRDA_LACAC
Sequence: MINTHITLPGLDLKNPVMPASGTFGFGDVPAAKKFDLNDLGAMVIKTTTPKATSGNPQPQIAVLDDGVLNSVGLTNPGVDQVISEKLVPLRKQYPNLPIMASVGGDSESDYVEVAKKLSDSDLVNALEINVSCPNVAQGGMSFGVHPDVVEELTKKIKDVVDVPIYVKLTPNVTDIVAIAQAAEKGGADGISMINTVLGMDIDVQTRRPVLGHNVGGLSGEAVKPIAIRMISQVYQNVTLPIIGMGGISSAEDVIKFMLAGASAVAVGTAHFNDSIASKHIADSLPAELEKLGIDDINDLVGQVKFN
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase A (fumarate), DHOD A, DHODase A, DHOdehase A.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_MICLC
Sequence: MKERIILAYSGGLDTSVAIGWIAEATGAEVVAVAVDVGQGGESLETIRQRALDCGAVEAYVADARDEFAEQYCMPTLKANALYMDAYPLVSAISRPVISRHLVAAARQFGASTVAHGCTGKGNDQVRFEVSIQTLGPDLKCIAPVRDLALTREKAIEYAERNDLPIVTTKKNPFSIDQNVWGRAVETGFLEDIWNGPTKDVYDYTDDPAFPPAPDVVTIAFERGVPTALDGRALSPLEIIEELNRRAGAQGVGRIDIVEDRLVGIKSREIYEAPGAMALIAAHRELENVTLEREQARFKKHVDQRWTELVYDGQWYSPLKRNLDTFIDATQEHVNGEIRLELHGGRATVQGRRSETGLYDFNLATYDEGDSFDQSSARGFIDIFGLSAKTASEREQRLRGSADLQDVARLSND
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_BURMA
Sequence: MTTGFLQKIFGSRNQRLVKQYQKTVAAINALETQIETLTDDQLRGKTGEFRQRIAAGESLDKLLPEAFAVCREASRRVLKMRHFDVQMIGGMVLHYGKIAEMRTGEGKTLVATLAAYLNALAGRGVHVVTVNDYLAQRDAEWMGRLYNFLGLSVGINLSGMEHDQKQAAYAADITYGTNNEFGFDYLRDNMVYETDSRVQRPLNFAVVDEVDSILIDEARTPLIISGQAEDHTELYVRMNALPPLLERQIGEEKADGTGVEKPGDYTLDEKGRQVFLTESGHEKAERMLAEWGLIGDGESLYAPQNITLMHHVYAALRAHTLFHRDQHYVVQNDEVIIVDEFTGRLMPGRRWSDGLHQAVEAKEHVKIQSENQTLASITFQNYFRMYAKLSGMTGTADTEAYEFNEIYGLETVVIPTNRPPKRIDKQDQIYKTAKERYDAVIRDIRECHERGQPVLVGTTSIENSELLSHLLKQAGLPHEVLNAKQHAREAAIVAEAGRPKRITIATNMAGRGTDIVLGGNVEKQAAFIEADESIPADEKARRIQQLHDEWETLHEQVKTAGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSLEDPLLRIFAGDRVRAIMDRLKMPEGEAIEAGIVTRSIESAQRKVEARNFDIRKQLLEYDDVSNDQRKVIYQQRNELLEAHDIAETIGAMRHGVISEVVRQFVPAGSIEEQWDLPELEETLRNDWQLDLAIQEMVNESSSINADEILDAVTTAADEHYEAKVALVGRESFSAFERSIMLQTLDRLWREHLAALDHLRQGIHLRGYAQKNPKQEYKREAFELFAAMLDAVKQEVTRIVMNVQIQSPEQLEEAAEQIEEQGGQLGNVEFQHADFAAAAAAATAGGAVVADATAEMVGHAMSHSGPAGEVPRVGRNDPCPCGSGKKYKHCHGKLN
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: OAT_BACAA
Sequence: MIQTKDIIELTDTYGANNYHPLPIVISKAEGVWVEDPEGNRYMDLLSAYSAVNQGHRHPKIINALIDQANRVTLTSRAFHSDQLGPWYEKVAKLTNKEMVLPMNTGAEAVETAIKTARRWAYDVKKVEANRAEIIVCEDNFHGRTMGAVSMSSNEEYKRGFGPMLPGIIVIPYGDLEALKAAITPNTAAFILEPIQGEAGINIPPAGFLKEALEVCKKENVLFVADEIQTGLGRTGKVFACDWDNVTPDMYILGKALGGGVFPISCAAANRDILGVFEPGSHGSTFGGNPLACAVSIAALEVLEEEKLTERSLQLGEKLVGQLKEIDNPMITEVRGKGLFIGIELNEPARPYCEQLKAAGLLCKETHENVIRIAPPLVISEEDLEWAFQKIKAVLS
What is the function of this protein?
Catalyzes the interconversion of ornithine to glutamate semialdehyde.
What are the official names of this protein?
Ornithine aminotransferase, OAT, Ornithine--oxo-acid aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.