PharMolix/UniProtQA huggingface dataset:
Protein: CHEB_SHIBS
Sequence: MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDLIKKFNPDVLTLDVEMPRMDGLDFLEKLMRLRPMPVVMVSSLTGKGSEVTLRALELGAIDFVTKPQLGIREGMLAYSEMIAEKVRTAAKASLAAHKPLSAPTTLKAGPLLSSEKLIAIGASTGGTEAIRHVLQPLPLSSPALLITQHMPPGFTRSFADRLNKLCQIGVKEAEDGERVLPGHAYIAPGDRHMELARSGANYQIKIHDGPVGMLAMRQAGAWTLAQNEASCVVFGMPREAINMGGVCEVVDLSQVSQQMLAKISAGQAIRI
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y6695_BRASO
Sequence: MEPSMIVVTTENVTGYRTVRMLGQCFGVVVRSRGIGGNFIASLRSIVGGEIHEYTQMLEEARRHALDRLVHNATSMGANAIVMMRFDSAEIGQTMSEIVAYGTAAVIEPAR
What are the official names of this protein?
UPF0145 protein BRADO6695.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: METN_VIBVU
Sequence: MIEINQVNKVFYQGSKEIHALKDINLHIAEGTIFGVIGSSGAGKSTLIRCVNMLEAPTSGSIVVDGVDLTKLSKKQLSETRRNIGMIFQHFNLLSSRTVFDNVALPLELAGKDKEQIQSKVTELLKLVGLADKHESYPANLSGGQKQRVAIARALASDPKVLLCDEATSALDPATTQSILELLKEINRKLKITILLITHEMDVVKSICHEVAIIGGGELVEKGTVGEIFAHPKTELAHDFIRSTLDLSIPEDYQVRLQPTRVAGSYPLVRLEFTGATVDAPLVSQISRKYNIDISILSSDLDYAGGVKFGMMVAELFGNEEDDNAAIEYLREHNVKVEVLGYVL
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: AOFB_CAVPO
Sequence: MNSKCDVVVVGGGISGLAAAKLLHDSGLNVVVLEARDCVGGRTYTLRNQNVKYVDLGGAYVGPTQNRILRLAKELGLETYRVNDVERQIHHVKGKSYPFRGPFPPAWNPISYLDHNNLWRTMDDMGKEIPSDAPWKAPLAEEWDHMTMKELLNKICWTNCPRQFGTLFVNLCFTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQISERIMNLLGDRVKLQRPVVYIDQTGESVLVETLNHEIYEAKYVISAIPPALGMKIHFKPPLPMMKNQLVSRVPLGSVIKCIVYYKDPFWRKKDFCGTMVIEGEEAPVLYTMDDTKPDGSYAAIIGFIAAHKARKLARLTKEERLKKLCELYAKVLGSKEALKPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRFLRQPVGRIFFAGTETATHWSGYMEGAVEAGERAAREVLNAIGKIPEDEIWQPEPESVDVPAQPITTTFLERHLPSVPGLLRLIRLTTVVSAVALGFLAQKRGLLLRI
What is the function of this protein?
Catalyzes the oxidative deamination of primary and some secondary amines such as neurotransmitters, and exogenous amines including the tertiary amine, neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), with concomitant reduction of oxygen to hydrogen peroxide and participates in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues.  Preferentially degrades benzylamine and phenylethylamine.
What are the official names of this protein?
Amine oxidase [flavin-containing] B, Monoamine oxidase type B, MAO-B.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side.
Protein: CSKP_DROME
Sequence: MTEDEILFDDVYELCEVIGKGPFSIVRRCIHRESNQQFAVKIVDVAKFTASPGLSTADLKREATICHMLKHPHIVELLETYSSEGMLYMVFEFMEGSDLCFEVVRRAVAGFVYSEAVACHYMRQILEALRYCHENDILHRDVRPACALLATVDNSAPVKLGGFGSAIQLPGTRETIETHGRVGCPHYMAPEVVTRRLYGKGCDVWGAGVMLHVLLSGRLPFLGSGVRLQQSVARGRLSFEAPEWKSISANAKDLVMKMLAANPHHRLSITEVLDHPWIRDRDKLQRTHLADTVEELKRYNARRKLKGAVQAIAGGTNMDPLYATDADMPITGATDEWADEEAGIEAVQRILDCLDDIYSLQDAHVDADVLRDMLRDNRLHQFLQLFDRIAATVVTSNGRAPAAEAVGRCRDVLEQLSSTSGGNSLGGKYAKEELMRLLAAPHMQALLHSHDVVARDVYGEEALRVTPPPMVPYLNGDELDNVEGGELQHVTRVRLVQFQKNTDEPMGITLKMTEDGRCIVARIMHGGMIHRQATLHVGDEIREINGQPVQHQSVGQLQRMLREARGSVTFKIVPSYRSAPPPCEIFVRAQFDYNPLDDELIPCAQAGISFQVGDILQIISKDDHHWWQARLDTVGGSAGLIPSPELQEWRIACQTVDKTKQEQVNCSIFGRKKKQCRDKYLAKHNAIFDTLDVVTYEEVVKVPVGDPNFQRKTLVLLGAHGVGRRHIKNTLISKYPDKYAYPIPHTTRPAKPEEENGRSYYFVSHDEMMADIGANEYLEYGTHEDAMYGTKLDTIRRIHTEGKMAILDVEPQALKILRTAEFTPYVVFIAAPSLQNIADYDGSLERLAKESEMLRQLYGHFFDLTIVNNDISETIATLETAIDRVHTTPQWVPVSWLY
What is the function of this protein?
May regulate transmembrane proteins that bind calcium, calmodulin, or nucleotides.  Functionally modulates eag potassium channels; increases eag current and whole-cell conductance.  Also regulates autophosphorylation of CaMKII.
What are the official names of this protein?
Peripheral plasma membrane protein CASK, dCASK, Calcium/calmodulin-dependent protein kinase, CAKI, Camguk.
What is the protein family that this protein belongs to?
Belongs to the MAGUK family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Note=Eag recruits CASK to the plasma membrane.
Protein: YGU4_SCHPO
Sequence: MGILKKTIFIGGIYGLGVYIGAVAWRLRKDVLNYESRQKSDLLIPNSNSISIYNQIADKYSRKITREEIFSGIYFLRYFLLRNAKGDVLEVGSGPGTNFPFYKWKKINTLTLVEPAEKMREIADARAKKKVPPNVLYRQFADLRQLPPNQSYDTIIQTFCICSQEKAVEQLNNYRSLLRSDGRILLIEHGKGKYKFLNRILNAYAESHYESWGCVWNRDIEQLLEDSELTIDSCKRFNFGTTYVIEAH
What is the function of this protein?
Probable methyltransferase.
What are the official names of this protein?
Uncharacterized methyltransferase C3B9.04, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METL family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: TS57_MYCTO
Sequence: MRNVRLFRALLGVDKRTVIEDIEFEEDDAGDGARVIARVRPRSAVLRRCGRCGRKASWYDRGAGLRQWRSLDWGTVEVFLEAEAPRVNCPTHGPTVVAVPWARHHAGHTYAFDDTVAWLAVACSKTAVCELMRIAWRTVGAIVARVWADTEKRIDRFANLRRIGIDEISYKRHHRYLTVVVDHDSGRLVWAAPGHDKATLGLFFDALGAERAAQITHVSADAADWIADVVTERCPDAIQCADPFHVVAWATEALDVERRRAWNDARAIARTEPKWGRGRPGKNAAPRPGRERARRLKGARYALWKNPEDLTERQSAKLAWIAKTDPRLYRAYLLKESLRHVFSVKGEEGKQALDRWISWAQRCRIPVFVELAARIKRHRVAIDAALDHGLSQGLIESTNTKIRLLTRIAFGFRSPQALIALAMLTLAGHRPTLPGRHNHPQISQ
What are the official names of this protein?
Transposase for insertion sequence element IS1557.
What is the protein family that this protein belongs to?
Belongs to the transposase 12 family.
Protein: RL1_SALDC
Sequence: MAKLTKRMRVIREKVDATKQYDINEAIALLKELATAKFNESVDVAVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGPNAEAAKAAGAELVGMEDLADQIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPSQAKGVYIKKVSISTTMGAGVAVDQAGLSASAN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RL2_SINMW
Sequence: MALKSFNPTTPSQRQLVIVSRAGLYKGKPVKTLTEGLSSKGGRNNLGRITVRFQGGGHKRTYRLVDFKRRKFDVEGTVERLEYDPNRTAFIALVNYADGEQAYILAPQRLAVGDKVIASEKAVDVKPGNAMPLQFIPVGSIIHNVEMKPGKGGQIARSAGTYAQLVGRDQGMAILRLNSGEQRLVHGSCLASIGAVSNPDHGNINDGKAGRSRWRGKRPHVRGVVMNPVDHPHGGGEGRTSGGRHPVTPWGKPTKGKRTRSNKSTDKFIMRSRHQRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: UBC6_SCHPO
Sequence: MASKGAYKRLMKEYLALQKNPVELVDAKPATENILEWHYIITGPPDTPYEGGQYHGTLIFPPDYPFKPPAIRMITPSGRFQTNTRLCLSFSDFHPKSWNPSWMVSTILVGLVSFMTSDEITTGGIVTSESTRRTYAKDTKRFNIMDNPKFLIMFPELIDKNREDIAKAAAEAALIEPQQIHSTPVSSNECKKNEPFNSKQSWVKSRWSIAVLVFFALALARFFGADS
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.  Functions in degradation of misfolded or regulated proteins localized in the endoplasmic reticulum (ER) lumen or membrane via the ubiquitin-proteasome system.  Cognate E2 conjugating enzyme for the doa10 ubiquitin ligase complex, which is part of the ERAD-C pathway responsible for the rapid degradation of membrane proteins with misfolded cytoplasmic domains.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 6, E2 ubiquitin-conjugating enzyme 6, Ubiquitin carrier protein 6, Ubiquitin-protein ligase 6.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane.
Protein: PG112_VAR67
Sequence: MEMDKRMKSLAMTAFFGELTTLDIMALIMSIFKRHPNNTIFSVDKDGQFMIDFEYDTYKASQYLDLPLTPISGDECKTHASSIAKQLACVDIIKEDISEYIKTTPRLKRFIKKYRNRSDTRISQDTEKLKIALAKGIDYEYIKDAC
What is the function of this protein?
Contributes to the formation of crescents and immature virions (IV).  Interacts with phosphatidylinositol-3-phosphate (PI3P) and phosphatidylinositol-4-phosphate (PI4P) lipids in order to form virion membranes.  Mechanistically, mediates proper formation of OPG125-hexamers, and hence the honey comb lattice and spherical immature virus.
What are the official names of this protein?
Late protein OPG112.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG112 family.
Protein: OR1A1_GORGO
Sequence: MRENNQSSTLEFILLGVTGQQEQEDFFYILFLFIYPITLIGNLLIVLAICSDVHLHNPMYFLLANLSLVDIFFSSVTIPKMLANHLSGSKSISFGGCLTQMYFMIDLGNTDSYTLAAMAYDRAVAISRPLHYTTIMSPRSCIWLIAGSWVIGNANALPHTLLTASLSFCGNQEVANFYCDITPLLKLSCSDIHFHVKMMYLGVGIFSVPLLCIIVSYIRVFSTVFQVPSTKGVLKAFSTCGSHLTVVSLYYGTVMGMYFRPLTNYSLKDAVITVMCTAVTPMLNPFIYSLRNRDMKAALQKLFNKRISS
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 1A1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYB_MOGIN
Sequence: MTNIRKTHPLMKIINNSFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMFMETWNIGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAGVHLLFLHETGSNNPSGLSSDTDKIPFHPYYTIKDILGALILILVLSSLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILALIPFLHTSKQRSMMFRPISQCLFWLLVADLLILTWIGGQPVEHPFIIIGQLASILYFSLILIMMPLASLMENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DADA2_RHILO
Sequence: MKITVLGAGVVGTAAAYYLAADGHEVTVIERHAAPARGTSQSNAGLVSPGDATAWASPAALKTFLRGLYNHDLGIKVRLRFDPYFLAWSLRFLRQCTVARLRANSQVKLRLALYSRDCINAISADTGIHYDERKKGILYFFRSQHSLNTGTDNYRYLAEHGLPIEIVGRDRLVELEPGLAGVKEKIAGGVYSPIDQTGDSRLFVDNLAAYASEKLGVKFLFGTTVEGLDIQGDRVRAVMTSAGPVTGDAVVISMGPESGLLGRRYGIDLPVYPVKGYTATIPLEDESKGPTIGGADEDQLMAYSRLGNRLRLASTAEFTGFDRTHKPSDFTTMFRTARDLFPGAFDEKKAELWAGLRPMMPGSVPVIGQARYKNLYLDTGHGHVGWTMACGSGKFLADLVAGRKPEIDPQGLVYGG
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: SYP_SHEON
Sequence: MRVSKYLLSTQKETPANAEVISHQLMLRAGMIRRNASGLYSYLPSGLRVLRKVEAIVREEMNKAGAIEILMPMVQPADLWVETGRWDKFGPELLRFKDRHNRDFVLGPTHEEVITDLIRKEVSSYKQLPLNLYQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHLDMDTLNETYEAMYQAYSNILSRMGLAFRPVLADTGSIGGSMSHEFHVLAQSGEDLIAYSTGSDYAANIEKAESPMPTETRGAATKELRLVDTPNAKTIAELVEQFGLDITKTVKTLIVKGATEEAPLVALIVRGDHELNEIKADKLDLVASPLEFAPEALIRDAIGAGPGSLGPVGLNMPIIIDHSVSVMSDFAAGANVDDKHYFGINWERDLPLAQAADIRNVVEGEPTPDGLGTYAMARGIEVGHIFQLGTNYSKSMNATVLDENGKSQVLLMGCYGVGVSRIVAAAIEQNFDDRGIVWPEAIAPFSVGILPMNMHKSHRVTDIAEQLYKDLSAAGIDVLLDDRKERPGVMFADMELIGIPHTVVIGDRNIDAGVFEYKNRRTGEKQDVPFDQIVDFLKNLQA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_DESHY
Sequence: MKVRPSVKKICEKCKVIKRHGKVMVICENPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: ISPH_THISH
Sequence: MQVILANPRGFCAGVDRAIDIVERALTLFGKPIYVRHEVVHNKFVVEDLRNKGAVFVEELDEVPDGATVIFSAHGVARSVVQEAERRGLRVFDATCPLVTKVHMEVDRHARRGEEVILIGHAGHPEVDGTLGQYDRSHGGEMYLVETVEDAERIQIRNPDALAYVTQTTLSVDDTLDIIETLKNRFPNIQGQKRDDICYATQNRQDAVKQLASECDLFLVVGSPNSSNSNRLREIAEKLGVEAYLVDNAGQIEDRWLEGKTRVGVTAGASAPELLVQEVVEHLRANGMNTVTEHGGTRENIVFSLPKALR
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: Y1909_NEIMA
Sequence: MNNSVITVIGKDRVGIVYDVSKILAENRINILNISQQLMDDFFTMIILVDTSKCSKSRQEVLDLFAEESKKLALDIRMQNEEIFQAMHRI
What are the official names of this protein?
UPF0237 protein NMA1909.
What is the protein family that this protein belongs to?
Belongs to the UPF0237 family.
Protein: MENE_STAA9
Sequence: MDFWLYKQAQQNGHHIAITDGQESYTYQNLYCEASLLAKRLKAYQQSRVGLYIDNSIQSIILIHACWLANIEIAMINTRLTPNEMTNQMRSIDVQLIFCTLPLELRGFQIVSLDDIEFAGRDITTNGLLDNTMGIQYDTSNETVVPKESPSNILNTSFNLDDIASIMFTSGTTGPQKAVPQTFRNHYASAIGCKESLGFDRDTNWLSVLPIYHISGLSVLLRAVIEGFTVRIVDKFNAEQILTMIKNERITHISLVPQTLNWLMQQGLHEPYNLQKILLGGAKLSATMIETALQYNLPIYNSFGMTETCSQFLTATPEMLHARPDTVGMPSANVDVKIKNPNKEGHGELMIKGANVMNGYLYPTDLTGTFENGYFNTGDIAEIDHEGYVMIYDRRKDLIISGGENIYPYQIETVAKQFPGISDAVCVGHPDDTWGQVPKLYFVSESDISKAQLIAYLSKHLAKYKVPKHFEKVDTLPYTSTGKLQRNKLYRG
What is the function of this protein?
Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).
What are the official names of this protein?
2-succinylbenzoate--CoA ligase, o-succinylbenzoyl-CoA synthetase, OSB-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
Protein: HIS4_ECO81
Sequence: MIIPALDLIDGTVVRLHQGDYGKQRDYGNDPLPRLQDYAAQGAEVLHLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQVGGGVRSEEDVAALLEAGVARVVVGSTAVKSPEMVKGWFERFGTDALVLALDVRIDEQGNKQVAVSGWQENSGVSLEQLVETYLPVGLKHVLCTDISRDGTLAGSNVSLYEEVCARYPQVAFQSSGGIGDIDDVAALRGTGVRGVIVGRALLEGKFTVKEAIACWQNA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAR1_ASPFN
Sequence: MSAILSADDLNDFISPGVACIKPVETLPKNESSNSQNPYEVTTEDKVQPENLPPAQISLTDCLACSGCVTSAEAVLISLQSHAEVLNTLDAYPELPLTQNHNGPYTGSSDALDGESRIFVASVSPQVRASLAATYGISEKEATYMIDQFLSGPHGLRAGGKHGSGFSWVVDTNVMRDAILVLTADEVSETLKEPSARAISKDTLPKRPVLSSACPGWICYAEKTHPFVLPHLSRLKSPQALTGTFLKTVLSKALGVPPSRVWHLAIMPCFDKKLEASREELTDVSWSPLDGGVPLTESNKPVRDVDCVITTRELLTLASSRGISLPTLPLKSLAPSYTPHFPDETLNAFLFRKQNGSEQSMEAGTSGGYLHHVLKTFQAKNPGSEIVTQRGRNADVVEYSLMSPGGEPLMKAARYYGFRNIQNLVRKLKPARVSRLPGARVPAASAGGNRRQPISRNSASAGSGTDYAYVEVMACPGGCTNGGGQIRIEDAREASTSTQSVTAVENPSKPTPHEQRAWLARVDEAYFSAESDAEAKWTVRHSPSPSLRGRLGSMKLSSIGLT
What is the function of this protein?
Component of the cytosolic Fe/S protein assembly machinery.  Required for maturation of extramitochondrial Fe/S proteins.  May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity).
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor nar1, Nuclear architecture-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the NARF family.
Protein: NADK_VARPS
Sequence: MTSRFRHVALIGKYQASGARAQADARDGVMEDIGAFLESQGCEVFVEKSAAEEADADASVGGRYQPLTVEEIGQRCDLGLVVGGDGTMLGIGRQLACYGIPLIGINRGRLGFITDIPLDNYQATLIPMLAGEYEEDHRSLMHAQVMRDGASVFDALAMNDVVVNRGATSGMVELRVSVGRHFVANQRADGLIIASPTGSTAYALSAGGPLLHPAVPGWVLVPIAPHTLSNRPVLLPDADEIVIELVAGRDASANFDMQSLASLAIGDRVVVRRSDFRVRFLHPRGWSYFDTLRKKLHWNEGGS
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_ECO45
Sequence: MKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLDDAVELAPGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVWNRGQDNFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RHMA_SALDC
Sequence: MNALLSNPFKEGLRKGDTQIGLWLSSTTSYMAEIAATSGYDWLLIDGEHAPNTVQDLYHQLQAIAPYASQPVIRPIEGSKALIKQVLDIGAQTLLIPMVDTAEQARQVVSATRYPPLGQRGVGASVARAARWGRIDNYMAQANESLCLLVQVESKVALENLDAILEVEGIDGVFIGPADLSASLGYPDNAGHPEVQRIIEACIYRIRAAGKAAGFLAVDPTMAQKCLAWGANFVAVGVDTMLYTEALDSRLAMFKSVQSVSTAKRSY
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of 2-keto-3-deoxy-L-rhamnonate (KDR) to pyruvate and lactaldehyde.
What are the official names of this protein?
2-keto-3-deoxy-L-rhamnonate aldolase, KDR aldolase, 2-dehydro-3-deoxyrhamnonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family. KDR aldolase subfamily.
Protein: TRMB_PEDPA
Sequence: MRVRNKPWAPELIEAHPEKIVEKGQAFKGQWNQRFEKEQPIFIEVGTGKGQFIINMAKKYPQYNFIGIEIQKTVIAIALKNALEEEIPNLQFLYADGAELTDYFEDGEVSKVFLNFSDPWPKTRHEKRRLTFKTFLKVYEQILVKNGEVEFKTDNQGLFEYSLYSLNNYGMTFEGVWLDLHNSEENEDNVETEYEHKFSAKGQPIYKLKAHF
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: FIS1_GIBZE
Sequence: MVTELPYALDAETPLNPSELNVLKAQYDREGEMVGVQTKFNYAWGLVKSNQRNDQQLGVRLLSDIFRVSPERRRECLYYLALGNYKLGNYGEARRYNDLLLDKEPANLQASNLRSLIDDKVAREGLMGVAILSGVGVAAGVVGAFLLRNARKR
What is the function of this protein?
Has a role in mitochondrial fission.  Has a role in outer membrane fission but not matrix separation (By similarity).
What are the official names of this protein?
Mitochondrial fission 1 protein.
What is the protein family that this protein belongs to?
Belongs to the FIS1 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: TX85E_ETHRU
Sequence: MKTNCEFPLLCLLIVLVANVEGEVEDNELKMVKRLWRNWEDPEQRQLLDQEAEQEKQREKRLWRNWEDLELRQLLNEFAENQREKRLWRNWERRQVANEDDGEKPKELWRNWEDLKRRQVVDLNDEQKTTG
What are the official names of this protein?
U-scoloptoxin-Er5e, U-SLPTX-Er5e, U-scoloptoxin-Er5-like, U-SLPTX-Er5-like, U-scoloptoxin-Er5.1c, U-SLPTX-Er5.1c.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-08 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CCG4_MOUSE
Sequence: MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGDLTHSGLWRVCCIEGIYRGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNHYNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKREFLKASSSSPYARMPSYRYRRRRSRSSSRSTEASPSRDASPVGLKITGAIPMGELSMYTLSREPLKVTTAASYSPDQDAGFLQMHDFFQQDLKEGFHVSMLNRRTTPV
What is the function of this protein?
Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity).  Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4.  Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization (PubMed:17880894).
What are the official names of this protein?
Voltage-dependent calcium channel gamma-4 subunit, Neuronal voltage-gated calcium channel gamma-4 subunit, Transmembrane AMPAR regulatory protein gamma-4, TARP gamma-4.
What is the protein family that this protein belongs to?
Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ORF2_TTVVG
Sequence: MFIGRHYRKKRALSLLAVRTTQKARKLLIVMWTPPRNDQQYLNWQWYSSVLSSHAAMCGCPDAVAHFNHLASVLRAPQNPPPPGPQRNLPLRRLPALPAAPEAPGDRAPWPMAGGAEGEEGGAGGDADHGGAAGGPEDADLLDAVAAAET
What are the official names of this protein?
Uncharacterized ORF2 protein.
Protein: RS16_BORT9
Sequence: MSVRIRLKRMGAKKRPYYRIVVMDSASPRDGRAIEELGYYHPVEKQNQVKINENKFRDWIGKGAIPSDTVKKILNKNNFKVES
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: CLAVD_STYCL
Sequence: MKTTILILLILGLGINAKSLEERKSEEEKAFKLLGRIIHHVGNFVYGFSHVFGDDQQDNGKFYGHYAEDNGKHWYDTGDQ
What is the function of this protein?
Has antimicrobial activity against E. coli, L. monocytogenes and C. albicans.
What are the official names of this protein?
Clavanin-D.
What are the subcellular locations of this protein?
Secreted.