PharMolix/UniProtQA huggingface dataset:
Protein: COXT_SOYBN
Sequence: ILCPLEAFIVQHILTISVMGLLSCFRSTVLRKCSKGSSGMSRFLYTNNFQRNLISSGGNESYYGYFNRRSYTSLYMGTGTVGGITSARIRVPNVGCEGFMCSSHLSITQRNSRLIHSTSKIVPNSEIQNITTEMVKTPEVSRWMDQVIPTIAPCDAAEPWQLGFQDAATPIMQGIIDLHHDIFFFVIQIGVFVSWVLLRALWHFRSKMNPIPQRIVHGTTIEILWTIFPSVILMFIAIPSFALLYSMDDIVVDPAITIKAIGHQWYWTYEYSDYNNSDEQSLAFDSYMIPEDDLELGQLRLLEVDNRVVVPAKTHLRVIITSADVLHSWAVPSLGVKCDAVPGRLNQISTFIQREGVYYGQCSEICGTNHAFMPIVIEAVSTKDYGSWVSSQVN
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, mitochondrial, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CRT_CLODI
Sequence: NSKKVVIAAVNGFALGGCELAMACDIRIASAKAKFGQPEVTLGITPGYGGTQRLTRLVGMAKAKELIFTGQVIKADEAEKIGLVNRVVEPDILIEEVEKLAKIIAKNAQLAVRYSKEAIQLGAQTDINTGIDIESNLFGLCFSTKDQKEGIVSFR
What are the official names of this protein?
Short-chain-enoyl-CoA hydratase, 3-hydroxybutyryl-CoA dehydratase, Crotonase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
Protein: RCOR_DROME
Sequence: MVLAERNTTDVVRNGRRSRGPSPNTHTTGGVTNSASLVGSGNNSGHSGNANANEKTTTAVPGAGTPESSDDDNSTKRNGKSKAKQSEYEEKIRVGRDYQAVCPPLVPEAERRPEQMNERALLVWSPTKEIPDLKLEEYISVAKEKYGYNGEQALGMLFWHKHDLERAVMDLANFTPFPDEWTIEDKVLFEQAFQFHGKSFHRIRQMLPDKSIASLVKYYYSWKKTRHRSSAMDRQEKAIKAVVKDGSENGSEVGSNEESDNDDKIQKNRQVMEQLDKECETINVDDVLSKPAAANTESAQPRISARWLPDEIQVALLAIREYGKNFPTIAKVVATKTEAHVRTFYLNNRRRYNLDQIVKEYEAGKSEESGAEEQTEPAVDAAAAGAATASAPSAADSTSAASATADRKQSTENSNNGVETMQESLPKKEDPKKPELAAAVLKIGVAEAADAVATVASSTASGVIGAATSASKPSTSATITIIDESDTATNSSSDVVTTGLATSTGSSALSSTTSAPASKTQTSSEELSAQKSNPASGIAAIGAATGGGQTANSSGSKRDSSVLPVAEQPPAKKIALSTGGGSSVAEFLAN
What is the function of this protein?
Essential component of a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells.  The BHC complex is recruited by Ttk88 and probably acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.  May serve as a molecular beacon for the recruitment of molecular machinery that imposes silencing across a chromosomal interval.
What are the official names of this protein?
REST corepressor, CoREST.
What is the protein family that this protein belongs to?
Belongs to the CoREST family.
Protein: TETO_CAMJU
Sequence: MKIINLGILAHVDAGKTTLTESLLYTSGAIAELGSVDEGTTRTDTMNLERQRGITIQTAVTSFQWEDVKVNIIDTPGHMDFLAEVYRSLSVLDGAVLLVSAKDGIQAQTRILFHALQIMKIPTIFFINKIDQEGIDLPMVYREMKAKLSSEIIVKQKVGQHPHINVTDNDDMEQWDAVIMGNDELLEKYMSGKPFKMSELEQEENRRFQNGTLFPVYHGSAKNNLGTRQLIEVIASKFYSSTPEGQSELCGQVFKIEYSEKRRRFVYVRIYSGTLHLRDVIRISEKEKIKITEMYVPTNGELYSSDTACSGDIVILPNDVLQLNSILGNEILLPQRKFIENPLPMIQTTIAVKKSEQREILLGALTEISDCDPLLKYYVDTTTHEIILSFLGNVQMEVICAILEEKYHVEAEIKEPTVIYMERPLRKAEYTIHIEVPPNPFWASVGLSIEPLPIGSGVQYESRVSLGYLNQSFQNAVMEGVLYGCEQGLYGWKVTDCKICFEYGLYYSPVSTPADFRLLSPIVLEQALKKAGTELLEPYLHFEIYAPQEYLSRAYHDAPRYCADIVSTQIKNDEVILKGEIPARCIQEYRNDLTYFTNGQGVCLTELKGYQPAIGKFICQPRRPNSRIDKVRHMFHKLA
What is the function of this protein?
Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.
What are the official names of this protein?
Tetracycline resistance protein TetO, Tet(O).
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. TetM/TetO subfamily.
Protein: MTND_SYNP2
Sequence: MTTLYQTESKQTLTDPATIKDFLKSHGIWFEQWETPAQLTQEASQADILAAYADVLDPFMAANGYQSADVVNIHSGIENYQAIREKFLAEHTHSEDEVRFFVAGQGLFWFNLDGTAVFNVCCEAGDLISVPQGTKHWFDAGPVPNVKAIRIFSDTAGWTPHYTGSQVEQQYRAITL
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: TRPA_SYNWW
Sequence: MEIRNRLAQLREKEEMALIAFIMAAVPDEDLCLDCIRALEQGGCDLLELGVPFTDPLADGEVIERFHHWGVRLGLNLKRGLDFAARVRAACQLPLILFSYYNPILQMGLDRFAGDCRSAGVDAVIVPDLPLDELGRLAGQGLELIPMLAPSSTLSRIQMAADLDPAFIYCVSVRGVTGVRSLPEMEIKDYLQKVRRVSTAPLALGFGISQPEQVRAFRGQADGVVIGSALAQIIEEYESRPALLPGMLEKRCQALKLLS
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RBM12_PONAB
Sequence: MAVVIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIVGGELGEAFIVFATDEDARLGMMRTGGTIKGSKVTLLLSSKTEMQNMIELSRRRFETANLDIPPANASRSGPPPSSGMSGRVNLPTTVSNFNNPSPSVVTATTSVHESNKNIQTFSTASVGTAPPNMGASFGSPAFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTPLPPMSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNLNPMFLGPLNPVNPIQMNSQSSVKPLPINPDDLYVSVHGMPFSAMENDVRDFFHGLRVDAVHLLKDHVGRNNGNGLVKFLSPQDTFEALKRNRMLMIQRYVEVSPATERQWVAAGGHITFKQNMGPSGQTHPPPQTLPRSKSPSGQKRSRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKAALCRHKQYMGNRFIQVHPITKKGMLEKIDMIRKRLQNFSYDQREMILNPEGDVNSAKVCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERLHRKKLNGREAFVHVVTLEDMREIEKNPPAQGKKGLKMPVPGNPAVPGMPNAGLPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPGPIHIGGPPGFASSSGKPGPTVIKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAVIDLNDRPIGSRKVNLY
What are the official names of this protein?
RNA-binding protein 12, RNA-binding motif protein 12.
What are the subcellular locations of this protein?
Nucleus.
Protein: PETL_ORYSJ
Sequence: MLTITSYFGFLLAALTLTLALFIGLNKIRLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: COA3_CANDC
Sequence: MGKLVGAPKGHDRYRDPKTHQITPALYRVRAPFFWRNTIALFAVSSIPLAVYLYTFKKMGDDDLGDIPIPPISDEELQKLKLEYENQK
What is the function of this protein?
Required for assembly of cytochrome c oxidase (complex IV).
What are the official names of this protein?
Cytochrome c oxidase assembly factor 3, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COA3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RAH1A_ARATH
Sequence: MGDLGKGYKLVFLGDQGVGKTSIITCFMYGKFDTSYQATIGIDFLSKTTRYEDRTFRLQLWDTAGQERFKSLVPSYIRDSSVAVIVYDVASKQSFINTSKWIEEVRAERGSYVIIVLVGNKTDLVNKRQVSIEEGENKAREFGALFMETSAKAGFNIKPLFCKITSALQGNEAVSWTKQEDLVDVNLKPLMFSSQANHQQESNCSC
What is the function of this protein?
Protein transport.  Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER) (By similarity).
What are the official names of this protein?
Ras-related protein RABH1a, AtRABH1a.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Lipid- anchor.
Protein: GSG1L_HUMAN
Sequence: MKTSRRGRALLAVALNLLALLFATTAFLTTHWCQGTQRVPKPGCGQGGRANCPNSGANATANGTAAPAAAAAAATASGNGPPGGALYSWETGDDRFLFRNFHTGIWYSCEEELSGLGEKCRSFIDLAPASEKGVLWLSVVSEVLYILLLVVGFSLMCLELFHSSNVIDGLKLNAFAAVFTVLSGLLGMVAHMMYTQVFQVTVSLGPEDWRPHSWDYGWSFCLAWGSFTCCMAASVTTLNSYTKTVIEFRHKRKVFEQGYREEPTFIDPEAIKYFRERMEKRDGSEEDFHLDCRHERYPARHQPHMADSWPRSSAQEAPELNRQCWVLGHWV
What is the function of this protein?
As a component of the inner core of AMPAR complex, modifies AMPA receptor (AMPAR) gating.
What are the official names of this protein?
Germ cell-specific gene 1-like protein, GSG1-like protein.
What is the protein family that this protein belongs to?
Belongs to the GSG1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Synapse.
Protein: PA2B_PROMB
Sequence: NLLQFNKMIKIMTKKNAIPFYSS
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that displays presynaptic neurotoxicity.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 mangshantoxin, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AROD_STRPG
Sequence: MRIVAPVMPRHFDEAQAIDISKYEDVNLIEWRADFLPKDEIVAVAPAIFEKFAGKEIIFTLRTVQEGGNITLSSQEYVDIIKEINAIYNPDYIDFEYFTHKSVFQEMLDFPNLILSYHNFEETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNYTRGFKTLNPEQEFATISMGKLGRLSRFAGDVIGSSWTYVSLDHVSGPGQVTLNDMKRIIEVLEMDISN
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: TEBA_STYMT
Sequence: MSSAKRSTSRVSKKKAAPAKDGAPKKREQSTRYKYVELNKASLTSAEAQHFYGVVIDATFPYKTNQERYICSLKVVDPSLYLKSQKGTGDASDYATLVLYAKRFEDLPIIHRIGDIIRVHRATLRLYNGQRQFNANVFYNSSWALFSTDKKSALQEIGGQEPASDLTPFAFSGKNYTFEKSEAALLQNIRKWAVQYFQQYNVISSDMFTPLNKAQAQKGDFDVVAKILQVFELDEYTNELKLKDQSGQVFYTLALKLKFPHLRAGEVVRIRSATYDETSTQKKVLLLSHYSNIVTFVSASKLAKEVKAKVTDDKSVEKAALKQDVSLSAVVLTEVDKKHAGLPTHSLQDLFHNADTDKEISSKDTFRTQFYITRVEPVDVKEWVKSYDRKTKKPSSHKGAGAKGGENIFQVQFLVKDASTQLNNNTYRVLLYTQDGLGANFFNVKPDNLYKNNDARKKLEEYNELLTKFNSYVDAVVERRNGFYFIKDTRIIF
What is the function of this protein?
May function as protective capping of the single-stranded telomeric overhang.  May also participate in telomere length regulation during DNA replication.
What are the official names of this protein?
Telomere-binding protein subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the telombin family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: FLD1_CAEEL
Sequence: MRQLAELLTDLLGPVPTMFLWVIVSFAFFRALQFIVRWYLFGKWTWPNFNFFDIRNRIRRRRRGGQEAENTENPPENEAEAGEQVEQEPEPDSRDLSAIPPNKKWRISNECVSLFHSVISGLWAAYALLYYKQLVQDLVNYRCDVAINLVLMSAGYLFHDLVDLLVNEQSARIIELLFHHVVVLSAFAVTMFFNRFLGVVVFGLLMELNSIFLHSRSLLNLYGVDKKSPSFRIIALLNMVTLFAFRLCVSAYLVYFVVVSIPDLEWYVSIINGLVIASLASTNTVLTYRLLAADGLLGSRRTRRTPAATAETQVGDVESGPLRTQVEDEDHHTIGVQTIHGTTEDATQTV
What is the function of this protein?
Regulates the composition and fluidity of the plasma membrane (PubMed:30509349).  Inhibits the incorporation of membrane-fluidizing phospholipids containing omega-3 long-chain polyunsaturated fatty acids (LCPUFA) and thereby promotes membrane rigidity (PubMed:30509349).  Does not appear to have any effect on LCPUFA synthesis (PubMed:30509349).
What are the official names of this protein?
TLC domain-containing protein fld-1, Membrane fluidity homeostasis protein 1.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARGE_YERPS
Sequence: MKMKLPPFIELYRALIATPSISAADSALDQSNEALINLLAGWFADLGFRVEIQPVPDTRHKFNLLASIGENENGEGHGGLLLAGHTDTVPYDEGRWTRDPFTLTEHDHKLYGLGTADMKGFFAFILDAVRDIDASKLTKPLYILATADEETTMAGARYFAANTQLRPDFAIIGEPTSLQPVRAHKGHISNAIRITGQSGHSSDPARGVNAIDLMHESITQLMALRTTLQERYHNPAFTIPYPTMNFGHINGGDAANRICACCELHMDIRPLPGLTLSDLNELMTEALEPVSQRWPGRLSIDELHPPIPGYECPTDHHMVGVIEKLLGERTAVVNYCTEAPFIQQVCPTLVLGPGSINQAHQPDEFIDMAFIEPTRELIGQLVDHFCQQK
What is the function of this protein?
Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids.  Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
What are the official names of this protein?
Acetylornithine deacetylase, AO, Acetylornithinase, N-acetylornithinase, NAO.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. ArgE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CINAL_TRIEI
Sequence: MIAEIICVGTELLLGDILNSNAQFLAKQLANLGIAHYYQTVVGDNPDRIKQVLAIATDRSQILIFTGGLGPTPDDLTVATIADFFETPLIERPEIIEDITKKFARRGRIMTASNRKQALIPQGANILPNPIGTAPGIIWQPVQNITIMTFPGVPTEMKSMWQETAIPYMQSQGWCEQTIYSRTLKFWGITESSLAEKVAPFLEKENPTVAPYANYGEVKLRISARATSLELANKLIIPVEEEIKDIAGIDFYGINDESLASVVGKLLLESGETLAVAESCTGGSLGSMLTSIPGSSEYFYGGVISYENQVKITLLDVNLEDLMAEGSVSHVVAKQMASGVVKKLGTNWGISITGIAGPGGGSDTKPVGLVYIGIARYDDIVESFEYRFSNLRDRNWIRRVSVSTALDLLRRKLYLSKQRPQHHQA
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: RK32_SACOF
Sequence: MAVPKKRTSMSKKRIRKNLWKKKTYFSIVQSYSLAKSRSFSSGNEHPKPKGFSGQQANK
What are the official names of this protein?
50S ribosomal protein L32, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NAGB_PECCP
Sequence: MRLIPLTTAADVGKWAARHIVEKINAFKPSAERPFILGLPTGSSPLEAYKSLVAMHQAGLVSFKHVVTFNMDEYVGLPTDHPESYHTFMHQNFFNHIDIPRENINLLNGNAEDTTAECRRYEEKIKSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIKTLTEETRIANSRFFGGDVSLVPKFALTVGVGTLLDAEEVMILVTGRNKALALQAAVEGNVNHMWTISCLQLHAKAIMVCDEPSTMELKVKTVKYFRELETESMKNL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: ARMX6_MOUSE
Sequence: MGRAREMGWMAAGLMIGAGACYCMYKLTMGRSEGNELEDEEEDEWEDGQDLDEEEADNWFDFTAMARPWSEDGDWDEPGAPGGTEDRRSGGGKANRAHPIKQRPFPYEHKNIWGEQSFKSFTCILDLNKCVSTQRKKRFTKNINAGFSLSPNISKHLASLSVVGNRSPTPHPTVREKALFVPENPNSSLENQGQIKMSIDEVCRETLLCCCKSFLQQAGLSLLISMTVINNMLAKSVSDLKFPLLSKGSGCAEVRGLEELMSLSEKPVLVGEALAAQMLSSFMCLFTRSGSREMLVEAISP
What is the function of this protein?
May regulate the dynamics and distribution of mitochondria in neural cells.
What are the official names of this protein?
Protein ARMCX6.
What is the protein family that this protein belongs to?
Belongs to the eutherian X-chromosome-specific Armcx family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion outer membrane; Single- pass membrane protein.
Protein: RS7_STRA1
Sequence: MSRKNQAPKREVLPDPLYNSKIVTRLINRVMLDGKRGTAATIVYDAFEAIKEATGTDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLRWLVNASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RS9_METS4
Sequence: MATLQSLADLGQANKAALGTAENEAPVHVQKLDAHGRAYATGKRKDAVARVWIKPGSGVITVNDRPVETYFARPVLRMILQQPLQVANRADQYDIVVTVTGGGLSGQAGAVRHGLAKALTHYEPELRSPLKREGFLTRDPRVVERKKYGRKKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: HPTR_STAAS
Sequence: MFKVVICDDERIIREGLKQIIPWGDYHFNTIYTAKDGVEALSLIQQHQPELVITDIRMPRKNGVDLLNDIAHLDCNVIILSSYDDFEYMKAGIQHHVLDYLLKPVDHAQLEVILGRLVRTLLEQQSQNGRSLASCHDAFQPLLKVEYDDYYVNQIVDQIKQSYQTKVTVSDLIQHIDVSESYAMRTFKDHVGITIVDYLNRYRILQSLQLLDRHYKHYEIADKVGFSEYKMFSYHFKKYLQMSPSDYCKQAK
What is the function of this protein?
Member of the two-component regulatory system HptS/HptR that regulates genes involved in hexose phosphate transport system in response to changes in extracellular phosphate sources.  Activates uhpT expression to facilitate glucose-6-phosphate/G6P utilization by directly binding to its promoter.  Antagonizes CcpA-dependent transcription of a subset of CcpA-regulated genes involved in antibiotic susceptibility.
What are the official names of this protein?
Transcriptional regulatory protein HptR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_FRAP2
Sequence: MRIILLGAPGAGKGTQAKIIEDKYNIAHISTGDMIRETIKSDSEIGKELKKVLDAGQLVSDEFIIKIVKDRISKDDCKNGFLLDGVPRTIIQAEELDKLGVNIDYIVEVDVKDNLLIERITGRRVHPASGRTYHTKFNPPKVEGKDDITGEDLITRTDDNEDTVRERLSVYHAQTSKLIDFYRNFSSTNTKTPKYIKIDGDQAVDKVSQDIFNQLK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYV_STAAM
Sequence: MEMKPKYDPREVEAGRYEEWVKNGYFKPSEDKSKETYTIVIPPPNVTGKLHLGHAWDTTLQDIITRMKRMQGYDTLYLPGMDHAGIATQAKVEAKLNEQGITRYDLGREKFLEQAWDWKEEYASFIRAQWAKLGLGLDYSRERFTLDEGLSKAVKKVFVDLYNKGIIYRGERIINWDPKARTALSDIEVIHEDVQGAFYHFKYPYADGEGFIEIATTRPETMLGDTAIVVNPNDERYKDVIGKTVILPIVGRELPILADEYVDIDFGSGAMKVTPAHDPNDFEIGQRHQLENIIVMDENGKMNDKAGKYEGMDRFDCRKQLVKDLKEQDLVIKIEDHFHSVGHSERSGAVVEPYLSTQWFVRMEDLAKRSLDNQKTDDRIDFYPQRFEHTFNQWMENIRDWTISRQLWWGHQIPAWYHKETGEIYVGEEAPTDIENWQQDEDVLDTWFSSALWPFSTLGWPDLESEDFKRYYPTNALVTGYDIIFFWVARMIFQGLEFTDRRPFNDVLLHGLVRAEDGRKMSKSLGNGVDPMDVIDEYGADSLRYFLATGSSPGHDLRYSTEKVESVWNFINKIWNGARFSLMNIGEDFKVEDIDLSGNLSLADKWILTRLNETIATVTDLSDKYEFGEVGRALYNFIWDDFCDWYIEMSKIPMNSNDEEQKQVTRSVLSYTLDNIMRMLHPFMPFVTEKIWQSLPHEGDTIVKASWPEVRESLIFEESKQTMQQLVEIIKSVRQSRVEVNTPLSKEIPILIQAKDKEIETTLSQNKDYLIKFCNPSTLNISTDVEIPEKAMTSVVIAGKVVLPLEGLIDMDKEISRLEKELAKLQSELDRVDKKLSNENFVSKAPEKVINEEKRKKQDYQEKYDGVKARIEQLKA
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNAJ_BACSU
Sequence: MLSENVKKISMVEKVGYASGDFACNLIYATVSTYLLFFYTDVFGLSAAAAGTMFLVVRIIDALADPFIGTIVDRTNSRFGRFRPYLLFGAFPFVILAILCFTTPDFSDMGKLIYAYITYVGLSLTYTTINVPYGALTSAMTRNNQEVVSITSVRMLFANLGGLVVAFFVPLLAAYLSDTSGNESLGWQLTMGILGMIGGCLLIFCFKSTKERVTLQKSEEKIKFTDIFEQFRVNRPLVVLSIFFIIIFGVNSISNSVGIYYVTYNLEREDLVKWYGLIGSLPALVILPFIPRLHQFLGKKKLLNYALLLNIIGLLALLFVPPSNVYLILVCRLIAAAGSLTAGGYMWALIPETIEYGEYRTGKRMGGLIYAIIGFFFKFGMALGGVVPGLVLDKFGYVANQAQTPAALMGILITTTIIPVFLLVLALIDINFYNLDEKKYKNMVRELENRDKVYLDHIDDFKA
What are the official names of this protein?
Uncharacterized symporter YnaJ.
What is the protein family that this protein belongs to?
Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL19_LACLM
Sequence: MNLIESINAAQLRTDIPDFRPGDTVRVHAKVVEGTRERIQIFEGVVIARKNSGINETYTVRKISNGVGVERIFPVHTPRVEKIEVIRHGKVRRAKLYYLRALTGKKARIAERRR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: PTH_HAES1
Sequence: MSEIKLIVGLGNPGDKYADTRHNAGEWLIERLARRFNFNLSVESKFSGKTARAVISGQEMRFLVPTTFMNLSGKAVSALANFYRIPPEQILVLHDELDFSPGIAKIKQGGGHGGHNGLKDIIAQLANNKNFYRLRIGIGHPGDKNLVASYVLNKPSPTDRQLIDRSLEEATDCIEILMKEGITKATNRLNAFKA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_PASMU
Sequence: MGQKVHPHGIRLGIVKPWSSTWFANTQDFADNLDGDFKVRKFLNKELANASVSRITIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRNAVAAIAGVPAQINIAEVKKPELDAKLVADSIASQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARSEWYREGRVPLHTLRADIDYNTAEAHTTYGVIGIKVWIFKGEILGGMAAIAQPEQQPADKPKKAPRGKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.