PharMolix/UniProtQA huggingface dataset:
Protein: NSD3_MOUSE
Sequence: MDFSFSFMQGIMGNTIQQPPQLIDSANIRQEDAFDNHSDIVEDGGPTPFEATLQQGFQYPPTTEDLPPLTNGYPPSISLYETQTKYPPYNQYPNGSANGFGAVRNFSPTDYYHSEIPNTRPHEILEKPSPPQPPPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNEVQASEHTKSKHESRKEKRKKSNRHESSRSEERRSHKIPKLEPEGQNRPNERVDTAPEKPREEPVLKEAIPVQPILSSVPTTETSTGVKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHSKINTRGAREYHVQFFSNQPERAWVHEKRVREYKGHEQYEELLAEAAKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERVEQYTFIYIDKQPEEASSQAKKNVTSKTEVKKPRRPRSVLNSQPEQTNAGEVASSQSSTDLRRQSQRRHTSLEEEEPPPVKIAWKTAAARKSLPASITMHKGSLDLQKCNMSPVVKIEQVFALQNATGDGKFIDQFVYSTKGIGNKTEISVRGQDRLIISSPSQRSEKPAQSASSPEATSGSAGPVEKKQQRRSIRTRSESEKSAEVVPKKKIKKEQVETAPQASLKTGLQKGASEISDSCKPLKKRSRASTDVETASCTYRDTSDSDSRGLSDGQVGFGKQVDSPSATADADASDAQSVDSSLSRRGVGTSKKDTVCQVCEKAGDCLVACEGECCRHFHVECLGLTAVPEGHFTCEECETGQHPCFSCKVSGKDVKRCSVSVCGKFYHEACVRKFPTAIFESKGFRCPQHCCSSCSMEKDIHKASKGRMMRCLRCPVAYHVGDACVAAGSVSVSSHILICSNHSKRSSQSAAINVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLSESNRAELMKLPMIPSSSASKKRCEKGGRLLCCESCPASFHPECLSIDMPEGCWNCNDCKAGKKLHYKQIVWVKLGNYRQVLWWPAEICSPRSVPLNIQGLKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDKHFAEGQTSINKTFKKALEEAAKRFQELKAQRESKEALEMERTSRKPPPYKHIKANKVIGKVQVQVADLSEIPRCNCKPGDENPCGLESQCLNRMSQYECHPQVCPAGDRCQNQCFTKRLYPDAEVIKTERRGWGLRTKRSIKKGEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTVTKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAGMELTFNYNLDCLGNGRTVCHCGADNCSGFLGVRPKSACTSAVDEKTKNAKLKKRRKVKAEAKPIHEDYCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPPHGKWECPWHRCDECGSVAVSFCEFCPHSFCKAHGKGALVPSALEGRLCCSSHDPASPVSPEYWSKIRCKWESQDSGEEVKE
What is the function of this protein?
Histone methyltransferase.  Preferentially dimethylates 'Lys-4' and 'Lys-27' of histone H3 forming H3K2me2 and H3K27me2.  H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression.
What are the official names of this protein?
Histone-lysine N-methyltransferase NSD3, Nuclear SET domain-containing protein 3, Wolf-Hirschhorn syndrome candidate 1-like protein 1 homolog, WHSC1-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: MTG1_MOUSE
Sequence: MRLWPQAWGAVRGAWRECFPLQGHDVARWFPGHMAKGLKKMQSSLKSVDCVIEVHDARIPFSGRNPLFQELLGLKPHLLVLNKMDLADLTEQQKIVQRLEEKGLSNVLFTNCVKDENIKQIVPKVMELIRCSYRYHRAETPEYCIMVVGVPNVGKSSLINSLRRQHLRTGKAARVGGEPGITRAVTSRIQVCERPLVFLLDTPGVLAPRIESVETGLKLALCGTVLDHLVGEETMADYLLYTLNRHGLFGYVQHYALASACDQIEWVLKNVAIKLRKTRKVKVLTGTGNVNVIQPDYAMAARDFLRTFRSGLLGQVMLDRDIIPAC
What is the function of this protein?
Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity (By similarity).  Displays mitochondrial GTPase activity (By similarity).
What are the official names of this protein?
Mitochondrial ribosome-associated GTPase 1, GTP-binding protein 7, Mitochondrial GTPase 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: FTSL_BACSU
Sequence: MSNLAYQPEKQQRHAISPEKKVIVKKRASITLGEKVLLVLFAAAVLSVSLLIVSKAYAAYQTNIEVQKLEEQISSENKQIGDLEKSVADLSKPQRIMDIAKKNGLNLKDKKVKNIQE
What is the function of this protein?
Essential cell division protein that may play a structural role.  Probably involved in the regulation of the timing of cell division.  Also required for sporulation.
What are the official names of this protein?
Cell division protein FtsL.
What is the protein family that this protein belongs to?
Belongs to the FtsL family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Localizes to the division septum where it forms a ring structure. Remains localized at mid-cell during the whole septation process. Localization requires FtsZ, DivIB, DivIC and PBP-2B.
Protein: QUEA_BORPA
Sequence: MPTPLTLADFDYHLPPELIAQSPAAERGGSRLLHLDAASRLHDRRFPDLAGLLRPHDLLVFNDTRVIKARLTGQKATGGKVEVLVERITAPDRALAHVRASKSPGPGMRLRLAEAFEAEVLGREGELFDLRFPAPVLDLLDAHGATPLPPYITHAADATDERRYQTVYAREPGAVAAPTAGLHFDQPMLEQLAAQGVQRAFVTLHVGAGTFQPVRVQNLAEHIMHAEWYTVPEATVAAIARARAHGGRIVAVGTTSVRALESAAAQAQDGPLAAAQGDTRLFITPGYRYRIVDALLTNFHLPQSTLLMLVSALAGVAPIRRAYAHAVAERYRFFSYGDAMFIETPAP
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU2C1_PELHO
Sequence: MLDSTRIFMKAFHLLLFDGSLIFPECILIFGLILLLMIDSTSDQKDIPWFYFISSTSLVMSITALLFRWREEPMISFSGNFQTNHFNEIFQFLILLCSTLSIPLSVEYIECTEMAITEFLLFILTATLGGMFLCGANDFITIFVAPECFSLCSYLLSGYTKKDVRSNEATMKYLLMGGASSSILVHAFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNGGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLSFLVSIGLLTSVLSIYYYLKIIKLLMTGRNQEITPHVRNYKRSPLRSKNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: AROE_XYLFM
Sequence: MPVSRFAVFGHPIAHSLSPRIHTEFGRQMGVALDYLAFDVAPDAFRVSLEHFVAEGGYGANVTLPLKEAAFEVCTTLSARARRAGAVNTLSRVDGVWHGENTDGIGLVRNLTERHGLDLRGRRALLLGAGGAARGVAPALLDAGITEMVIVNRSPERADMLCDALGEPGRVSARYWGDLGDLGNFELIVNATSIGNTSDMRTFSLPRSLLDSMTVAVDLNYGSAAVPFLAWAHAVETRYAIDGLGMLVEQAAESFSLWHGRRPDTDPVYTVLHSEYGVPGRS
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: RNT_CITK8
Sequence: MSDNAQLSGLCDRFRGFYPVVIDVETAGFNAKTDALLEVAAITLKMDEQGWLMPDTTLHFHVEPFEGANLQPEALAFNGIDPSNPLRGAVSEYDALHAIFKMVRKGIKDSGCNRAIMVAHNATFDHSFMMAAAERASLKRNPFHPFVTFDTAALSGLALGQTVLSKACLAAGMEFDGTQAHSALYDTERTAVLFCEIVNRWKRLGGWPLPVPEEA
What is the function of this protein?
Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang.  Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A).  Also appears to be involved in tRNA biosynthesis.
What are the official names of this protein?
Ribonuclease T, Exoribonuclease T, RNase T.
What is the protein family that this protein belongs to?
Belongs to the RNase T family.
Protein: CBPM_ECOL5
Sequence: MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPSEIQETTWVFDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDIAHLKQENRLLRQRLSRFVAHP
What is the function of this protein?
Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA.  Together with CbpA, modulates the activity of the DnaK chaperone system.  Does not inhibit the co-chaperone activity of DnaJ.
What are the official names of this protein?
Chaperone modulatory protein CbpM.
What is the protein family that this protein belongs to?
Belongs to the CbpM family.
Protein: CDKB_CONVX
Sequence: MPKLAVVLLVLLILPLSYFDAAGGQAVQGDWRGNRLARDLQRGGRDDESECIINTRDSPWGRCCRTRMCGSMCCPRNGCTCVYHWRRGHGCSCPG
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.  This toxin specifically blocks mammalian neuronal nAChR of the alpha-7/CHRNA7 (IC(50)=0. 4 nM), alpha-3-beta-2/CHRNA3-CHRNB2 (IC(50)=8. 4 nM) and alpha-4-beta-2/CHRNA4-CHRNB2 (IC(50)=228 nM) subtypes.  VxXXB inhibits alpha-7/CHRNA7, alpha-3-beta-2/CHRNA3-CHRNB2 and alpha-4-beta-2/CHRNA4-CHRNB2 nAChR subtypes more efficiently than VxXXA and VxXXC.
What are the official names of this protein?
Alpha-conotoxin VxXXB, Vx20.2, VxXIIB.
What is the protein family that this protein belongs to?
Belongs to the conotoxin D superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DLDH_BUCBP
Sequence: MISKKVDTQVVIIGSGPSGYSAAFRCSDLGLNVVLIEQYYSLGGVCLNVGCIPSKYLLHIAKVIKDVKKLSRIGISFEKLDINLKEIQCNQKKIIESFSSGISNLARKRNVRIIFGYAKFLDANSIFVQGEHDSYVVSFNKIVIATGSLSKKLSYIPYDDIRIWNSSFAVSIPSIPKKLLIIGGGIIGLEMATIYSALGSNVDIIDNSHDILPHLDRDVIDIFKRSVNHDYNIFFNSNVIKIVQEKNGLLVHIAENDNKNKRFELYDIILVAIGRVPNTDMLDISKVGLKTDNNGFIKVNEQFCTNIPNIYAIGDVIGQPMLAHKGTHEGHIVAEVISGKKHYFNPFVIPCVSYTEPEIAWVGITENEARKNNINYEVSSVLWNTLGRAVSSQCSEGVTKLIFDKKTNKIIGGCIVGSNAGELLGEISLAIEMGCDAEDLALTIHAHPTLYESINLSAQIFQGTITDLINKKIKK
What is the function of this protein?
Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes.
What are the official names of this protein?
Dihydrolipoyl dehydrogenase, Dihydrolipoamide dehydrogenase, E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTSRB_HUMAN
Sequence: MESPLIYVSVLLLNIFEFSSGIVYNKDDTEKRFACSNKGFPQENEIIKLYLFLENLKIQCFFQTENEIASKAMLSVFTSGGLAPSLGIMNSTYNGIFHFNLTLFSDRILWLVDIPRENITQSTDIAAVEEWLVRITLHHGLNIYATEGTLLDVIREPILQWTPGDVIPESEISKLYPHVVDLKVTKCPCANDVALLGFIVDTIVDGVYIGITFGGFWHDYDTTWFNMTQTIYSQLQEEYEDLSLVDMVLTNHFLVILTSLGLFVSEDLRYPSRHSLSFSRADFCGFERVDYVKGKLWYNERCFANREHFEVDYVTVTFERNRTLSESSSCFYSQEPFLEWVPCLPHIFKGIKIFPTVLTFLVDQERGTGVYLFYNKVRKTAIASVSTLRNNEPNSQSKFPIFRFPSSFSSPVGMVFHPRSHFLYAYGNQIWLSVDGGNTFQLIANFHDDIIKKTFHSFYTSAITFVSQRGKVYSTKAGMGRYSAVGSVTERIFTLYYDHLGFLHKLTLGRFEASGPPTAFGNSRNLFGQPPDMGFETALAPQHTSLDEIIFFAYVPENEPQETIYSKKFGNIHYGKVIHSGKTGRAYIRKVLQHTTPKGFLSSVIAEMKEPFGLEEVNESSCLSSSLLINKAGNVYKLTLDSQVVQALFEDTDIEKTVVLPGYSSFLITSILDNKNALAIATMPESAPNNMTFLKSTWFLYNFGQRNGRTWKIYSKPCNYWFQHDDSPSLNIVKYIDLGNSYVLKAKVIRNAKGFRMLEIPLLTVFVGNPNLLEVTAEVTFDDTDSYVITISAASKVLHQGSTSLAFIMWSASTECFVTTMVPTLKSSCSYLRSMHHIPSKFIPFEDWISGVHKDSQGFNLIKTLPINYRPPSNMGIAIPLTDNFYHADPSKPIPRNMFHMSKKTGKFKQCANVSTREECNCTKDQKFSHAVAFSDCREKVPRFKFPITQYPVSLEIINEDGRVPLQSPYLVTVTEVNMRHNWKLKHTVPENIKRMKQLVEPILGAAVYNPSGLNLSIKGSELFHFRVTVISGVTFCNLIEEFQIYVDEAPLPFPGHTLIAVATAVVLGGLIFIAFMFQLQGIHPWRTFQRWIRRNQEKFSSISLSELIHRSKSEE
What is the function of this protein?
Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation.  Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization.
What are the official names of this protein?
Cation channel sperm-associated auxiliary subunit beta, CatSper-beta.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum membrane; Single-pass membrane protein. Note=Predominantly located in the principal piece of the sperm tail.
Protein: TXSS1_PSETR
Sequence: LFGGLLDKLKEKIKKYCNKENLDKACSKL
What is the function of this protein?
This heterodimer may have anti-inflammatory properties, since the myrmexin complex (composed of 6 SS-LS heterodimers) inhibits carrageenin-induced edema in a dose-dependent manner (after subcutaneous injection into rats).
What are the official names of this protein?
U1-pseudomyrmecitoxin-Pt1 subunit SS1, U1-PSDTX-Pt1 subunit SS1, Myrmexin I subunit SS1/Myrmexin II subunit SS1, U1-pseudomyrmecitoxin-Pt1a subunit SS1/U1-pseudomyrmecitoxin-Pt1b subunit SS1, U1-PSDTX-Pt1a subunit SS1/U1-PSDTX-Pt1b subunit SS1.
What is the protein family that this protein belongs to?
Belongs to the myrmexin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PLSY_DECAR
Sequence: MQIAIALVAAYLLGSVPFAMISSKLFGLADPRTYGSGNPGATNVLRSGNKKAALVTLIGDALKGWAAVFIAQRMGFSDNVIGLVALAVFLGHLYPIFLKFKGGKGVATAAGVLIALDPMLGLAVAGTWLFMAYAFRYSSLAAVVAAAMAPVISVLMHGGNGQTVVVGILGMALIGKHWQNIQRLMAGQESKIGSKKKA
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LGT2_STRCO
Sequence: MDLAYLPSPSTGVLHLGPIPLRAYAFCIILGVFAAVWLGNRRWVARGGKQGVIADVTLWAVPFGLVGGRLYHVFTSPDAYFGERGEPVRALYVWEGGLGIWGAIALGAVGAWIGCRRHRIPLPAFADAVAPGIVLAQAIGRWGNWFNQELYGRPTTLPWGLEIDRAHRPAGTLDIATYHPTFLYESLWNIGVAALILWAAKRFPLGHGRTFALYVAAYTVGRFGTEYLRIDEAHTFLGLRLNNWTSVLVFLGAVACLVVSAHRHPGIENVARLQGAGADGRTDDPRPADASVGLASGPPGNSTPRRATESWNVRNRS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase 2.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RIR1_BPT4
Sequence: MQLINVIKSSGVSQSFDPQKIIKVLSWAAEGTSVDPYELYENIKSYLRDGMTTDDIQTIVIKAAANSISVEEPDYQYVAARCLMFALRKHVYGQYEPRSFIDHISYCVNAGKYDPELLSKYSAEEITFLESKIKHERDMEFTYSGAMQLKEKYLVKDKTTGQIYETPQFAFMTIGMALHQDEPVDRLKHVIRFYEAVSTRQISLPTPIMAGCRTPTRQFSSCVVIEAGDSLKSINKASASIVEYISKRAGIGINVGMIRAEGSKIGMGEVRHTGVIPFWKHFQTAVKSCSQGGIRGGAATAYYPIWHLEVENLLVLKNNKGVEENRIRHMDYGVQLNDLMMERFGKNDYITLFSPHEMGGELYYSYFKDQDRFRELYEAAEKDPNIRKKRIKARELFELLMTERSGTARIYVQFIDNTNNYTPFIREKAPIRQSNLCCEIAIPTNDVNSPDAEIGLCTLSAFVLDNFDWQDQDKINELAEVQVRALDNLLDYQGYPVPEAEKAKKRRNLGVGVTNYAAWLASNFASYEDANDLTHELFERLQYGLIKASIKLAKEKGPSEYYSDTRWSRGELPIDWYNKKIDQIAAPKYVCDWSALREDLKLFGIRNSTLSALMPCESSSQVSNSTNGYEPPRGPVSVKESKEGSFNQVVPNIEHNIDLYDYTWKLAKKGNKPYLTQVAIMLKWVCQSASANTYYDPQIFPKGKVPMSIMIDDMLYGWYYGIKNFYYHNTRDGSGTDDYEIETPKADDCAACKL
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase subunit alpha, Protein B1, Ribonucleotide reductase.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase large chain family.
Protein: LFTR_CHLTE
Sequence: MIKVEDILRAYRHGFFPMADSREGTVSWCQPYQRAVVPLDSFRPSRSLRRVIGKKRFTIKINSVFEQVIRACSQPRSTGQETWLSEEIIKVFLKLHRLGVAHSVESWQDGELAGGLYGLSMGGAFFGESMFFFRSDASKVAFAWLVGYLKRKGYLLLDAQIMNPHLESLGAIEIPHEEYMVQLERALGKKISFV
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_ROYRE
Sequence: MRTNPTTSSPVVSTLEEKNLGRIAQIIGPVLDVVFPPGKMPNIYNALVVKGRDTVGQQINVTCEVQQLLGNNRVRAVAMSATDGLMRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEKNIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRVLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQRVKQTSQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGNIDEATAKAMNLEVESKLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: PER1_VOLCA
Sequence: MMRKALLALCVATAFAVAQAQNVAYPNFPYCQCIKSPSPYSLEPVVKSNRTGQYCFTLRVTKPSPSATGYCATKADIKKIEINVNQVCDVFGNVVNATLNGVPTKVGPAFDTPPDGPNTSRILRFTQLNLGLDSDGAMLCITLGQNDKGKGCTTLEDLCAPPAGAPKGTCSLALFDSKPDCCPISRVSPPAPPPPPPPPPPEPVAVPITPPCKTCVYATITALPPLLFPFQLTPSICQSVADKIAGDLEMIVTSYSIGYSGATITCSGNVIKVCASFSLPPGAPYTGLQADISNALTFWLSLLAPSTGCPAYFANHQVTVTVGGDGDPNSVTCLEGTATTTCKPGNPDFPKCECETKPAATRFAALPTLTQEPGRPSNRTNSTLYCFTLQVVAPLNPNGLCGNTTTLLKAELWGNDIPTQRRKILALAFKAAGASSPLRYLSPSWGSAGEQTLKVSGLNWDASQADGAKICMELSNDTNLKTFCNTGQDTCWINLFSPDKQCCPLFAASLTP
What is the function of this protein?
May be involved in conversion of asexual males and females to the sexual pathway.
What are the official names of this protein?
Perphorin-1, Perphorin I.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: HEMA_I89A2
Sequence: MKTIIALSYILCLVFAQKLPGNDNSTATLCLGHHAVPNGTLVKTITNDQIEVTNATELVQSSSTGRICDSPHRILDGKNCTLIDALLGDPHCDGFQNKEWDLFVERSKAYSNCYPYDVPDYASLRSLVASSGTLEFINEDFNWTGVAQSGESYACKRGSVKSFFSRLNWLHESEYKYPALNVTMPNNGKFDKLYIWGVHHPSTDREQTNLYVRASGRVTVSTKRSQQTVIPNIGSRPWVRGLSSRISIYWTIVKPGDILLINSTGNLIAPRGYFKIRTGKSSIMRSDAPIGTCSSECITPNGSIPNDKPFQNVNRITYGACPRYVKQNTLKLATGMRNVPEKQTRGIFGAIAGFIENGWEGMVNGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRLIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTRKQLRENAEDMGNGCFKIYHKCDNACIGSIRNGTYDHDVYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLLCVVLLGFIMWACQKGNIRCNICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: RCH1_CANAL
Sequence: MSLETFRESKAYKWTSKVISFLIGQWFFIFLGVFIALAHSYPEFAKQGGTIRAEYSIGYGAVAVIFLISGLSMSTKQLLVNVANWRAHFTVLSMSFLVTSAIIYGIASGIKASHNGQIDDWLLIGLIVTHACPTTVSSNVVMTKQAHGNDILTLCEVFIGNVLGAFITPALLQMYMRGTWEIGNPSHQTQGDSTVQELYAHTMKQLGLSVFVPLFVGQVVQNIFPKQTKWCLTTFKLNKVGSFMLLLIMFQSFSTAFAQHAFTSVSHASIIFLVFFNIGIYLFFTVLTFFYSRPFWILRVFKEEPNESSSKLYRYSYAFFRPFYYNRKDTVAVMLCGPAKTAALGVSLVSSQYGSHNPKLGIILVPLVLYQAEQVMTANVLVSFMRKWIHAEDKVPEDEETSVGSDNDPKK
What is the function of this protein?
Solute carrier protein that negatively regulates the cytosolic homeostasis in response to high levels of extracellular calcium.
What are the official names of this protein?
Solute carrier RCH1, Regulator of calcium homeostasis 1.
What is the protein family that this protein belongs to?
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Bud neck. Note=Distributes as multiple foci in the plasma membrane prior to cell division, moves toward and concentrates at the bud neck as the bud grows in size, and disperses again along the plasma membrane immediately prior to cytokinesis.
Protein: CTRC_NEIMA
Sequence: MKELHKTSFLESLLIQKRVIGALLMREIITRYGRNNIGFLWLFVEPLLLTLVMVLMWKFFRMHNVSALNIVAFTLTGYPMMMMWRNASNHAIGSISANTSLLYHRNVRVLDTIFARMLLEIAGATIAQVVIMFALVIIGWIDVPADIFYMLLAWLLMAMFAVGLGLVICSVAFHFEPFGKVWSTISFVMMPLSGVFFFVHNLPQQLQHYVLMIPMVHGTEMFRAGYFGDSVTTYENPWYILLCNLVLLLLGLAVVARFSKGVEPQ
What is the function of this protein?
May form an ATP-driven capsule polysaccharide export apparatus, in association with the CtrB and CtrD proteins.
What are the official names of this protein?
Capsule polysaccharide export inner-membrane protein CtrC.
What is the protein family that this protein belongs to?
Belongs to the ABC-2 integral membrane protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PROA_PSEFS
Sequence: MTESVLDYMTRLGRAARQASRLIARASTAQKNRALLAAADALDASRSELTAANEQDLANGRANGLEPALLDRLALTPARIDDMIEGLRQVAKLPDPIGEIRDMRYLPSGIQVGKMRVPLGVIGIIYESRPNVTIDAASLCLKSGNATILRGGSEAINSNRAIAACIQQGLAVAELPAEVVQVVETTDRAAVGALITMPEFVDVIVPRGGKSLIERVSRDAKVPVIKHLDGVCHVFIDIAADIDKAIRIADNAKTHRYAPCNTMETLLVHVGIADRVLPPLAAIYRDKGVELRGCERTRALLGADVIEATELDWYTEYTAPILSIKIVDDLDEAIEHINTYGSKHTDAIVSEHFSDARRFLNEVDSASVMINASTRFADGFEYGLGAEIGISTDKLHARGPVGLEGLTSEKYVVFGDGHVRT
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FXL22_HUMAN
Sequence: MWPLLTMHITQLNRECLLHLFSFLDKDSRKSLARTCSQLHDVFEDPALWSLLHFRSLTELQKDNFLLGPALRSLSICWHSSRVQVCSIEDWLKSAFQRSICSRHESLVNDFLLRVCDRLSAVRSPRRREAPAPSSGTPIAVGPKSPRWGGPDHSEFADLRSGVTGARAAARRGLGSLRAERPSETPPAPGVSWGPPPPGAPVVISVKQEEGKQGRTGRRSHRAAPPCGFARTRVCPPTFPGADAFPQ
What is the function of this protein?
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.  Promotes ubiquitination of sarcomeric proteins alpha-actinin-2 (ACTN2) and filamin-C (FLNC).
What are the official names of this protein?
F-box and leucine-rich protein 22.