PharMolix/UniProtQA huggingface dataset:
Protein: KAX55_HOTTA
Sequence: AFCNLRRCELSCRSLGLLGKCIGEECKCVPH
What is the function of this protein?
Blocks small conductance calcium-activated potassium channels.
What are the official names of this protein?
Potassium channel toxin alpha-KTx 5.5, Tamapin-2.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 05 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GMHA_PSEE4
Sequence: MDMQSRIRRLFQASIDTKQQAMDILAPHIEQASLVMVNALLSDGKMLACGNGGSAGDAQHFSSELLNRFERERPSLPAIALTTDSSTLTSIANDYSYNEVFSKQIRALGQPGDVLLAISTSGNSANVIQAIQAAHDREMIVVALTGRDGGGMASLLLPEDVEIRVPSTVTARIQEVHLLAIHCLCDLIDSQLFGSEE
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_CHLAA
Sequence: MEELIAIVGPTAVGKTELAVAWARRINGEIVSADSRQIYRWMDIGTAKPSPEEQAQAPHHLIDIRDPDQPFSLAEFCDLATAAIADIRGRGRIPLLVGGTGQYLAAFLEGWQVPRVAPQPDLRAELELIAAREGPAVLHARLAAVDPVAASRIPPTNVRRVVRALEVYLVSGEPISRLQERKEPPFRPRTIWLHRPRAELYARADARIERMIAAGLVEEVAGLLARGYDWSLPAMSSLGYIQFRPYFTGEADLPTCIERLRFDTHAFIRRQEMWFRRLPNLEIWTPDHPSWREITA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: CEP85_HUMAN
Sequence: MAMQEKYPTEGISHVTSPSSDVIQKGSSLGTEWQTPVISEPFRSRFSRCSSVADSGDTAIGTSCSDIAEDFCSSSGSPPFQPIKSHVTIPTAHVMPSTLGTSPAKPNSTPVGPSSSKLPLSGLAESVGMTRNGDLGAMKHSPGLSRDLMYFSGATGENGIEQSWFPAVGHERQEEARKFDIPSMESTLNQSAMMETLYSDPHHRVRFHNPRTSTSKELYRVLPEAKKAPGSGAVFERNGPHSNSSGVLPLGLQPAPGLSKPLPSQVWQPSPDTWHPREQSCELSTCRQQLELIRLQMEQMQLQNGAICHHPAAFGPSLPILEPAQWISILNSNEHLLKEKELLIDKQRKHISQLEQKVRESELQVHSALLGRPAPFGDVCLLRLQELQRENTFLRAQFAQKTEALSREKIDLEKKLSASEVEVQLIRESLKVALQKHSEEVKKQEERVKGRDKHINNLKKKCQKESEQNREKQQRIETLERYLADLPTLEDHQKQSQQLKDSELKSTELQEKVTELESLLEETQAICREKEIQLESLRQREAEFSSAGHSLQDKQSVEETSGEGPEVEMESWQKRYDSLQKIVEKQQQKMDQLRSQVQSLEQEVAQEEGTSQALREEAQRRDSALQQLRTAVKELSVQNQDLIEKNLTLQEHLRQAQPGSPPSPDTAQLALELHQELASCLQDLQAVCSIVTQRAQGHDPNLSLLLGIHSAQHPETQLDLQKPDVIKRKLEEVQQLRRDIEDLRTTMSDRYAQDMGENCVTQ
What is the function of this protein?
Acts as a negative regulator of NEK2 to maintain the centrosome integrity in interphase.  Suppresses centrosome disjunction by inhibiting NEK2 kinase activity (PubMed:26220856).
What are the official names of this protein?
Centrosomal protein of 85 kDa, Cep85, Coiled-coil domain-containing protein 21.
What is the protein family that this protein belongs to?
Belongs to the CEP85 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Nucleus, nucleolus. Note=Localizes to centrosomes and nucleolus in interphase. Upon entry into mitosis, relocates from nucleolus and accumulates at spindle poles (PubMed:21399614). Associated with the pericentriolar material. Localizes to centrosomes at a low level in G1 phase and a slightly increased level in S phase, with gradually elevated levels during G2 phase. The levels at centrosomes further increase at G2/M, reaching a peak at spindle poles at early mitotic stages and remain high until the end of anaphase (PubMed:26220856).
Protein: P2C03_ORYSJ
Sequence: MSSPSPSSEAAAAHHHHHQRRQHAGAAGGSGLVPLAALIKEEARAERPMGSGSRICARDEEDGGGGGGAEGGRRWRRPLLRYGCAAQSKKGEDFFLLRTDCARPSTSSSSSSSLASSPPHTFAVFAVLDGHNGNAAAIYTRDNLLNHVLSAMPRGLSREEWLHALPRALVAGFVKTDKEFQHKGQTSGTTATFVIIDGWTITVASVGDSRCILDAQGGAVSLLTVDHRLEENVEERERVTASGGEVGRLSVVGGAEIGPLRCWPGGLCLSRSIGDIDVGEFIVPVPYVKQVKLSNAGGRLIIASDGIWDALSSEAAAKCCRGLPAELAAKQVVKEALRTRGLKDDTTCIVVDMIPPDQTIRHPSPPKKINKLKSLIFRKKTKDHPNKLTKQLSAAGMVEELFEEGSAMLSERLGNDSSGRRTSSSLFTCAICQVDLEPSEGISVHAGSIFSSSSSKPWEGPFLCSDCRDKKDAMEGKRPSGVKVL
What are the official names of this protein?
Probable protein phosphatase 2C 3, OsPP2C03.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: S38A2_XENTR
Sequence: MNNAEVLNVALDEDSSNSNDDLNYSEYQPKNHPIKSHYDMDIENVHFLLEPTMSKKKCETEYLPGTTSFGMSVFNLSNAIVGSGILGLSYAMANTGIALFMILLVFVTVFSLYSIHLLLKTANEGGSLLYEQLGLKAFGIPGKLAASGSVTLQNIGAMSSYLYIVKYELPLVIKALMDIKESNGEWYLNGDYLVIMVSLAIILPLSLLRNLGYLGYTSGFSPLCMVFFLIVVIYKKFEIPCPLEAMNMTSNSSSHDHMAHNETDDEMCKPKYFVFNSQTVYAVPILTFSFVCHPAVLPIYQELKGRSRRRMMNVSNVSFFAMFIMYLLAALFGYLTFYSKVEPELLHTYSKVFGAGVIFVVVRLAVLMAVTLTVPIVIFPIRSSLNELFCSGKDFAWIRHILITFLILAFTNVLVIFVPTIRDIFGFIGASAAAMLVFILPSAFYIRLVKKESMKSVQKIGALLFLIGGIIVMIGSMTLIILDWIHNSTSGGN
What is the function of this protein?
Symporter that cotransports neutral amino acids and sodium ions from the extraccellular to the intracellular side of the cell membrane.  The trasnport is pH-sensitive, Li(+)-intolerant, electrogenic, driven by the Na(+) electrochemical gradient and cotransports of neutral amino acids and sodium ions with a stoichiometry of 1:1.
What are the official names of this protein?
Sodium-coupled neutral amino acid symporter 2, Amino acid transporter A2, Solute carrier family 38 member 2, System A amino acid transporter 2, System A transporter 1, System N amino acid transporter 2.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y5224_ARATH
Sequence: MANLPTVLVTGASGRTGQIVYKKLKEGSDKFVAKGLVRSAQGKEKIGGEADVFIGDITDADSINPAFQGIDALVILTSAVPKMKPGFDPTKGGRPEFIFEDGQYPEQVDWIGQKNQIDAAKVAGVKHIVVVGSMGGTNPDHPLNKLGNGNILVWKRKAEQYLADSGTPYTIIRAGGLLDKEGGVRELLVGKDDELLQTDTKTVPRADVAEVCIQALLFEEAKNKAFDLGSKPEGTSTPTKDFKALFSQVTSRF
What are the official names of this protein?
Uncharacterized protein At5g02240.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Protein: ALR_CLOP1
Sequence: MDICVRPVWAEIDLDIIANNMKEIRNLVGEKEIIAVVKANAYGHGALDIASTLLENGASRLAVAIITEADELRDAGITAPIMILGYTPINFAENLINNEIEQTVYDVEYAKELSDFALKLGKKAKVHIAIDTGMGRIGFLPNEEGLNKVLEICSLPGVEVIGLFTHFSTSDEKDKTYTYEQFSKLTAFNKALEDNGIHIPLKHASNSGAIMDLPETYLDGVRCGIISYGYYPSEEVKKENLKLKPALTLKTNVAFVKELDEDMYVSYGRTYKTEKKSKIATLPIGYADGYSRLLSGKAKVIIKGQFANVIGRVCMDQCMIDVTHIEDVKIGDEVILLGEENGLKFDANDMAEIMGTINYEILCMISHRVPRIYKKNNEIVKVINYI
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: RPA49_HUMAN
Sequence: MAAEVLPSARWQYCGAPDGSQRAVLVQFSNGKLQSPGNMRFTLYENKDSTNPRKRNQRILAAETDRLSYVGNNFGTGALKCNTLCRHFVGILNKTSGQMEVYDAELFNMQPLFSDVSVESELALESQTKTYREKMDSCIEAFGTTKQKRALNTRRMNRVGNESLNRAVAKAAETIIDTKGVTALVSDAIHNDLQDDSLYLPPCYDDAAKPEDVYKFEDLLSPAEYEALQSPSEAFRNVTSEEILKMIEENSHCTFVIEALKSLPSDVESRDRQARCIWFLDTLIKFRAHRVVKRKSALGPGVPHIINTKLLKHFTCLTYNNGRLRNLISDSMKAKITAYVIILALHIHDFQIDLTVLQRDLKLSEKRMMEIAKAMRLKISKRRVSVAAGSEEDHKLGTLSLPLPPAQTSDRLAKRRKIT
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase I which synthesizes ribosomal RNA precursors (PubMed:24207024).  Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF (PubMed:24207024).
What are the official names of this protein?
DNA-directed RNA polymerase I subunit RPA49, RNA polymerase I subunit A49, DNA-directed RNA polymerase I subunit E, RNA polymerase I-associated factor 1, RNA polymerase I-associated factor 53.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
Protein: SUB7_ARTBC
Sequence: MGFITKAIPLALAAASVINGAEIMETRAGVQTLADKYIVVMNDGMTDKDFDSHRSWVNRTHRRRLIRRGAKAMGGMKHTYRFPTGLKGYSGHFDEQMINEISKRADVKYIERDARVQINAIEQQDNVPSWGLARVGSKEPGGTTYYYDGTAGEGSTAYVIDTGTDIQHEEFEGRATWGANFVDDMDMDCNGHGTHVSGTIGGKTFGVAKKSNVVAVKVLDCNGSGSNSGVIMGMEWATKDAQQKGADKAVANMSLGGAFSQASNDAAAAIAKGGVFLAVAAGNDNVDAADSSPASEPSICTVAASTEQDSKADFSNFGQVVDVYAPGDSITSAKPGGGSQVLSGTSMATPHVAGLGAYLIGLGKGGGPGLCDTIKQTAIDVIQNPGASTTSKLINNGSGIGFLSFPLNIYEEQWSKLFDL
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease 7.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: YN042_YEAST
Sequence: MILALGDFLPKQEDKACERPWVQFPARPVIFFHHQGGIFLFSINQPNLSCFSKLKEVNSLYVRVATYICQKNESRFRTNRLKGDQ
What are the official names of this protein?
Uncharacterized protein YNL042W-B.
Protein: PLSY_BLOPB
Sequence: MIFFSILITIFAYFLGSISSAILICKILRFPDPRNFGSKNPGATNILRIAGLKIAISVILFDILKGAIPMWLGYHLKISPIFLGATAVFSCLGHMYPIFFKFYGGKGVATAFGVLTTIDLHLSIVMISSWTLTVLSFGYSSLGAIVTAFIIPCYAWHFQSQYLLPTIIISSLVVIKHAANIKRLWHHKENRIWRK
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISPH_PSEA8
Sequence: MQIKLANPRGFCAGVDRAIEIVNRALDVFGPPIYVRHEVVHNKFVVDNLRQRGAIFVEELDQVPDNVIVIFSAHGVSQAVRKEAEGRGLKVFDATCPLVTKVHMEVVRYSRDGHECVLIGHEGHPEVEGTMGQYDASNGGAIYLVEDEADVAALEVRKPEALHYVTQTTLSMDDTSKVIDALRAKFPQIQGPRKNDICYATQNRQDAVKELADQCDMVLVVGSPNSSNSNRLRELAERMGTPAYLIDGAEDMQRGWFDGVRRIGITAGASAPEVLVRGVIAQLREWGASEEQELEGREENITFSMPKELRVKAL
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: EFP_BRAHW
Sequence: MLPVNDLRKGDAIILDGETYLVVDAHFHRAQQRKANVKTKLKNMLKGNMIEKTFSSTESVEEADLSYKKAQYLYEEGDSYVFMILDNYEQVHVSADILGDSKYYLLDSCEVDLQYINDEVTAVRFPIHVILEVTYTEPGFKGDTTGSTLKPAKLETGIEVNVPLFINIGDKIKVDTRDDSYVERVNK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCNQ_XENLA
Sequence: MEIGKNNMDTCNMASSDKDVKIHFKVARFIMEAGVKLGMHSVPIATACTIYHKFYKETSLENYDPHLVAMSAIYLAGKVEEQHLRTRDIINVCHRYNNPGSEPLEVDSKFWELRDNIVHCELLMLRMLNFRVSFQHPHKYLLHYLISLKNWMNRHSWERTPIATAAWALLRDSYHGDLCLRYEPQQIAVAVLYFALQCYGVEVPSNSNAETSWWQVFSEDITILTINNIISDLIHIYTMDTEIV
What is the function of this protein?
May be an activating cyclin for the cyclin-associated kinase CDK10.
What are the official names of this protein?
Cyclin-Q, Cyclin-related protein FAM58A.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin-like FAM58 subfamily.
Protein: RFC1_DROME
Sequence: MQRGIDSFFKRLPAKAKSAEAENGETPSKAPKRRKAVIISSDEDEVVSPPETKKRKASKTASSEDDVVAATPEPIAKKARNGQKPALSKLKRHVDPTELFGGETKRVIVPKPKTKAVLEFENEDIDRSLMEVDLDESIKEAAPEKKVHSITRSSPSPKRAKNSSPEPPKPKSTKSKATTPRVKKEKPAADLESSVLTDEERHERKRASAVLYQKYKNRSSCLNPGSKEIPKGSPDCLSGLTFVVTGVLESMEREEAESVIKEYGGKVMTVVGKKLKYLVVGEEAGPKKLAVAEELNIPILSEDGLFDLIREKSGIAKQVKEEKKSPKKEHSSEEKGKKEVKTSRRSSDKKEKEATKLKYGEKHDIAKHKVKEEHTSPKETKDKLNDVPAVTLKVKKEPSSQKEHPPSPRTADLKTLDVVGMAWVDKHKPTSIKEIVGQAGAASNVTKLMNWLSKWYVNHDGNKKPQRPNPWAKNDDGSFYKAALLSGPPGIGKTTTATLVVKELGFDAVEFNASDTRSKRLLKDEVSTLLSNKSLSGYFTGQGQAVSRKHVLIMDEVDGMAGNEDRGGMQELIALIKDSSIPIICMCNDRNHPKIRSLVNYCYDLRFQRPRLEQIKGKIMSICFKEKVKISPAKVEEIIAATNNDIRQSINHIALLSAKEDASQKSGQQVATKDLKLGPWEVVRKVFTADEHKHMSFADKSDLFFHDYSLAPLFVQQNYLQVLPQGNKKDVLAKVAATADALSLGDLVEKRIRANSAWSLLPTQAFFSSVLPGEHMCGHFTGQINFPGWLGKNSKSGKRARLAQELHDHTRVCTSGSRLSVRLDYAPFLLDNIVRPLAKDGQEGVPAALDVMKDYHLLREDLDSLVELTSWPGKKSPLDAVDGRVKAALTRSYNKEVMAYSYSAQAGIKKKKSEAAGADDDYLDEGPGEEDGAGGHLSSEEDEDKDNLELDSLIKAKKRTTTSKASGGSKKATSSTASKSKAKAKK
What is the function of this protein?
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1.  This subunit binds to the primer-template junction (By similarity).
What are the official names of this protein?
Replication factor C subunit 1, Activator 1 140 kDa subunit, Activator 1 subunit 1, Germline transcription factor 1, Replication factor C large subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 large subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COBQ_THEYD
Sequence: MAKLLMIQGTSSNCGKSLIVTALCRITKNRGIKVAPFKAQNMSLQSFITEDGGEIGLAQAIQAEAAGVVPNVHMNPVLLKPSGQQGIQIVVHGKLYKTLNSIDFYSEKKKLWENVTDSLNYLLKEHDFLIIEGAGSPAEINLLEKDIVNMAVAEYLKAPVILVGDIDRGGVFASLYGTVKLLEKYDSLFKGFIINKFRGHVDILSPGIKKLEELINKPCLGVVPYLDETGISDEDGVSMRLINFFAQKVNAPVKIVVLRLRYISNFNDFEPLRFEPDTELMYSLKKEDLLSADIIIIPGSKKTFEDLKLLRELKIDQTLRELAKNGVEIIGICGGFQMLGEKLIDPYMVESSLREFDGIGLLPVETLFYPEKITTQVEGCLCSEPSIKITGYEIHKGITYGHLGLFKITRTSMNQTLFDGIVCGNVWGTYIHGIFESDSLRRWLINRHRVKKGLNPIDYSFSWKKLKESFIDTLANTIEKNLDINRVWEIAGL
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: SURE_BRUA4
Sequence: MRILLTNDDGIHAEGLAVLERIARKLSDDVWVVAPETDQSGLAHSLTLSEPLRLRQIDDRHFALRGTPTDCVIMGVRHVLPGAPDLILSGVNSGANIADDVTYSGTVAGAMEGTLLGVRSIALSQEYEYEGDRRIVPWETAETHAPDLIKKLMEAGWPEGVLLNLNFPNCGADEVKGTRVTAQGKLSHDARLDERRDGRGFPYFWLHFGRGKAPVADDSDIAAIRSDCISVTPLHLDLTAHKVRAELSAALGVVELGG
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_RHOPB
Sequence: MTASLKAIDGAADPGAELAAMMTALGAQARAAARVLAIAPTAQKNEALAAMERAIRAHTPAILQANAEDVAEARAGGATDAFIDRLTLTEARVAVMADGIGVIHDIADPVGQVTERWQRPNGMTIERVRVPLGVIAVIFESRPNVAADAGVLALKSGNAVILRGGSDSFRSCRAIHDCLVEGLREAGLPEAAITRVPVRDRAAVGLLLGGLDGNVDVIVPRGGKSLVARVEAEARVPVFAHLEGINHVYVDRAADLDMAKSIVLNAKMRRPGVCGAAETLLIDRAAASNLAPLVTTLLEAGCEVRGDDAVQRVDPRVKPVAEEDWDTEYEAAIMSVKLVDGVDAALAHIAQHGSHHTEAIVTADQSVASKFLNEVDAAIVLHNASTQFADGGEFGFGAEIGIATGKFHARGPVGAEQLTSFKYRVHGTGQIRP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1062_PYRAB
Sequence: MDLGSKPLIGVVHLLPLPGSPGYRGSIEEILDRAISDAAKYQEAGFDAIILENYGDFPYSKTISKETLASFAVIAKEVGREISIPIGINVLRNDCVASYSIAYSVRADFIRVNVLTGVAFTDQGIIEGCARELAELRARLPSRIKVLADVHVKHATHFSSFEVALLDTVERGGADAVIITGSRTGSEVDIQELMLAKKISPVPVIVGSGLNPRNIRLFWRYADGFIVGTWVKEGGKTLNEVSLERATRIAKVVKSLRGE
What are the official names of this protein?
Uncharacterized protein PYRAB10620.
What is the protein family that this protein belongs to?
Belongs to the BtpA family.
Protein: SOSB2_RAT
Sequence: MHGVNDPPLFIKDIKAGLKNLNVVFIVLEIGRVTKTKDGHEVRSCKVADRTGSITISVWDEIGGLIQTGDIIRLTRGYASMWKGCLTLYTGRGGELQKIGEFCMVYSEVPNFSEPNPDYRGQQNRVVQNEQKDKMNTSIFGTVGNGVQTGPESRGYPLQYGRSNGPGPISPQLPGEPSNQTVRTTISNARDPRRAFKR
What is the function of this protein?
Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint.  In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines.  The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability.  Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways (By similarity).
What are the official names of this protein?
SOSS complex subunit B2, Nucleic acid-binding protein 1, Oligonucleotide/oligosaccharide-binding fold-containing protein 2A, Sensor of single-strand DNA complex subunit B2, Sensor of ssDNA subunit B2, SOSS-B2, Single-stranded DNA-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the SOSS-B family. SOSS-B2 subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to nuclear foci following DNA damage.
Protein: RS5_ZYMMO
Sequence: MANESEIQKTENAEVANAANGTNPNNERRGRGGRGRGGRGRDGRGRRDDRRNEEAGEELIEKLVHINRVSKTVKGGKRFGFAALVVVGDGKGRVGFGHGKAREVPEAISKATAAAKKTMIRVPLREGRTLHHDGRGRFGAGLVYLRSAPSGTGIIAGGPMRAIFESLGVADVVTKSVGTSNPYNMIRATFEALNDQKSPKAVAQRRGKRIADLFGRGGASAAKAEAEAAAVVE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: PSD_ECO24
Sequence: MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKYYKVDMKEAQKPDTASYRTFNEFFVRPLRDEVRPIDTDPNVLVMPADGVISQLGKIEEDKILQAKGHNYSLEALLAGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYVPGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTITPPREGIIKRWTWPAGENDGSVALLKGQEMGRFKLGSTVINLFAPGKVNLVEQLESLSVTKIGQPLAVSTETFVTPDAEPAPLPAEEIEAEHDASPLVDDKKDQV
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CS047_RAT
Sequence: MGFRIRESLLLNLRKVPGSRVKARETMVSVTMATSEWIQFFKEAGIPPGPAVNYAVMFVDNRIQKSMLLDLNKEIMNELGVTVVGDIIAILKHAKVVHRQDMCKAATASVPCTPSPLQGELRRGASSAASRMIANSLNHDSPPHTPARRSDNSTSKISVTVSNKVAVKNAKAAALAHREEESLVVPTKRRRVTAEMEGKYIIHMPKGTTPRTRKILEQQQAAKGLHRTSVFDRLGAETKADTTTGTKPTGVFSRLGATPEMDEELAWDSDNDSSSSSVLQYAGVLKKLGRGPTKASPQPALTVKAKATSSATTLASTPKLRRLALPSRPGPEKKPESLPKVSILKRLGKAAVVSEAQDSQVTSTKSPTVRCIVPDPPAPLASQRPPRRRWRRTCKDC
What are the official names of this protein?
Uncharacterized protein C19orf47 homolog.
Protein: TGT_ECOL5
Sequence: MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPEEVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIRKITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAKRSRERFDSLGNKNALFGIIQGSVYEDLRDISVKGLVDIGFDGYAVGGLAVGEPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRKAIEEGKLESFVTDFYQRQGREVPPLNVD
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: IPKG_MOUSE
Sequence: MMEVESSYSDFISCDRTGRRNAVPDIQGDSEAVSVRKLAGDMGELALEGAEGQAEGSTPDKEASSQPESSDANTSS
What is the function of this protein?
Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.
What are the official names of this protein?
cAMP-dependent protein kinase inhibitor gamma, PKI-gamma.
What is the protein family that this protein belongs to?
Belongs to the PKI family.
Protein: TRHO_PSEA7
Sequence: MTSIVVAALYKFVTLDDYVALREPLLQTLLDNGVKGTLLLAEEGINGTVSGSREGIDALFAWLRSDPRLADIEHKESYCDEQPFYRTKVKLKKEIVTLGVPGVDPNKRVGQYVEAKDWNALISDPEVLLIDTRNDYEVAIGTFEGAVDPKTRSFREFPEYIKAHYDPARHKKVAMFCTGGIRCEKASSYMLGAGFEEVFHLRGGILKYLEEVPQEQSLWRGDCFVFDNRVTVRHDLSEGEYDQCHACRNPVSVEDRQSEHYVPGISCPHCWDSLSEKTRAGARERQKQIELARQRNQPHPLGRDPRQSTLEN
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: YNAJ_ECOL6
Sequence: MIMAKLKSAKGKKFLFGLLAVFIIAASVVTRATIGGVIEQYNIPLSEWTTSMYVIQSSMIFVYSLVFTVLLAIPLGIYFLGGEEQ
What are the official names of this protein?
Uncharacterized protein YnaJ.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RLMH_BACC1
Sequence: MNISIISIGKLKEKYLKQGIAEYLKRLSAYAKVEVIELPDEKAPENLSEAEMLIVKEKEGIRILDKISDDTHVIALAIEGKQKSSEEFAVSLDRLATYGKSKVAFVIGGSLGLSSEVIKRSNESLSFSKMTLPHQLMRLVLLEQVYRAFRINRGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.