PharMolix/UniProtQA huggingface dataset:
Protein: AAAD_RAT
Sequence: MGRTIFLLISVVLVAYYIYIPLPDDIEEPWKIILGNTLLKLGGDLASFGELLGLNHFMDTVQLFMRFQVVPPTSDENVTVMETDFNSVPVRIYIPKRKSTTLRRGLFFIHGGGWCLGSAAYFMYDTLSRRTAHRLDAVVVSTDYGLAPKYHFPKQFEDVYHSLRWFLQEDILEKYGVDPRRVGVSGDSAGGNLTAAVTQQILQDPDVKIKLKVQALIYPALQALDMNVPSQQENSQYPLLTRSLLIRFWSEYFTTDRDLEKAMLLNQHVPVEFSHLLQFVNWSSLLPQRYKKGYFYKTPTPGSLELAQKYPGFTDVKACPLLANDSILHHLPMTYIITCQYDVLRDDGLMYVKRLQNTGVHVTHHHIEDGFHGALTLPGLKITYRMQNQYLNWLHKNL
What is the function of this protein?
Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly (By similarity).  Displays serine esterase activity in liver.  Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity.
What are the official names of this protein?
Arylacetamide deacetylase.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Microsome membrane; Single-pass type II membrane protein.
Protein: GLGB_SYNY3
Sequence: MTYTINADQVHQIVHNLHHDPFEVLGCHPLGDHGKVNQWVIRAYLPTAEAVTVLLPTDRREVIMTTVHHPNFFECVLELEEPKNYQLRITENGHERVIYDPYGFKTPKLTDFDLHVFGEGNHHRIYEKLGAHLMTVDGVKGVYFAVWAPNARNVSILGDFNNWDGRLHQMRKRNNMVWELFIPELGVGTSYKYEIKNWEGHIYEKTDPYGFYQEVRPKTASIVADLDGYQWHDEDWLEARRTSDPLSKPVSVYELHLGSWLHTAYDEPVKTLHGEGVPVEVSEWNTGARFLTYYELVDKLIPYVKELGYTHIELLPIAEHPFDGSWGYQVTGYYAPTSRFGSPEDFMYFVDQCHLNGIGVIIDWVPGHFPKDGHGLAFFDGTHLYEHGDPRKGEHKEWGTLIFNYGRNEVRNFLVANALFWFDKYHIDGMRVDAVASMLYLDYCREEGEWVANEYGGRENLEAADFLRQVNSVVYSYFPGILSIAEESTSWPMVSWPTYVGGLGFNLKWNMGWMHDMLDYFSMDPWFRQFHQNSITFSMWYNHSENYMLALSHDEVVHGKSNMLGKMPGDEWQKYANVRALFTYMFTHPGKKTMFMSMEFGQWSEWNVWGDLEWHLLNFPPHQQLKQFFTELNHLYKNEPALYSNDFDESGFQWIDCSDNRHSVVSFIRRAKNSAEFVVTICNFTPQPHSHYRVGVPVPGFYTELFNSDARQYGGSNMGNLGGKWTEEWSFHEQPYSLDLCLPPLSVLVLKLSQNAEENTVPAEEASNIA
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: MIAA_CHLP8
Sequence: MSQKPVLVILGPTASGKTELAFRIARKTGGEIISADSRQIYRSMDIGTAKPPKWMLNEVKHHFIDEKEIGEPFSAGDFAEQAAERIRELRQRGITPIVAGGSTLYLEGLLKGFAELPQSNPEIRARLKHELELHGAEALYRRLEAFDPEQAKTLDPTKTQRLIRSLEIIEISGTTVTALQRKTSGPPPGIEFTVIALDLPREVLYERINRRTSEMMHAGLEAETRHLFDKFRDEWRSKKLNALATVGYRELFEHFEGLYNLETAEALIAQHTRNYAKRQLTFFRNRLDVEWVKGPLDEAGIEALVESLCEKIA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: CYB_GARNE
Sequence: MAPNLRKSHPLLKMINNSLIDLPTPSNISAWWNFGSLLGLCLVTQILTGLLLATHYTADTTLAFSSVTHTCRNVQYGWLIRNLHANGASFFFICIYLHIGRGLYYGSYLYKETWNTGILLLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTIVEWAWGGFSVDNPTLTRFFALHFLLPFMIAGLTLIHLTFLHESGSNNPLGLVSNCDKIPFHPYFSLKDTLGFMFMLFLLTTLALFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLILFLSPLLHKSKQRTMAFRPFSQFLFWLLIANLLILTWVGSQPVEHPFIIIGQLASLTYFTILLILLPITGALENKMLNY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NSP1_ROTH6
Sequence: MATFKDACYQYKKLNKLNNAILKLGANDVWRSSTLTKRKGWCLDCCQHTDLTYCQGCLIYHVCEWCSQYSRCFLDDDPHLLRMRTFRNEVTKSDLENLINMYDTLFPINQKIVNKFTNIIKQHKCRNEYLTQWYNHFLMPITLQSLSIELDGDIYYIFGYYDDMHKINQTPFSFANLINKYDVLLLDSINFDRMAFLPLTLQQEYALRYFSKSRFITERRKYIETLHFSDNILNNLHNPNFTLQVIRNCSNMSVEWNKACNLIRNISDYFDILKSSHTESYNISPRCRMFTQYKLKIASKLIKPNYVASNHNSLATEVHNCKWCSINNNSIVWTDFRIKNVYNDVFNFIRALVKSNLYVGHCSSEERIYESIKDILNVCKENEWNMLVTEIFNQLDPIKLNEDSYVLLNYEINWNVMNVLINSIGKIPKILTLNDVISILRIIIYDWFDIRFMRNTPMTTFTVNKLKQLYEKDKTAEYDSGISDVE
What is the function of this protein?
Plays a role in the inhibition of host innate immunity by inducing the degradation of key host factors required to activate interferon production such as IRF3, IRF5 or IRF7.  Associates with components of cullin RING ligases (CRLs) including CUL1 or CUL3, which are essential multisubunit ubiquitination complexes, to modulate their activities.  Recognizes the host NF-kappa-B regulator BTRC through the presence of a DSGXS motif in the C-terminal substrate recognition domain.
What are the official names of this protein?
Non-structural protein 1, NSP1, NCVP2, Non-structural RNA-binding protein 53, NS53.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP1 family.
What are the subcellular locations of this protein?
Host cytoplasm, host cytoskeleton.
Protein: NTPTH_HYPBU
Sequence: MHSYVVVTGRPGVGKTTLFWKVVRKLMDEGVVVKGFYCPEVRGQQGYRIGFKIVLLDGSGEAWLARREGCNGPRVGRYYTCPEAETIASRVLGELGKADLIAIDEIGPMELRLAGVRRTIYRVLDSGKPGLFVVHERLSDPYILARLKPSGVWFHVTIENRDVLPEKVYEAVKQAVARSKGVGELSL
What is the function of this protein?
Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP.  May hydrolyze nucleoside diphosphates with lower efficiency.
What are the official names of this protein?
Nucleoside-triphosphatase THEP1, NTPase THEP1, Nucleoside triphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the THEP1 NTPase family.
Protein: TBC12_XENTR
Sequence: MVGPEDAGQGAVYRCGEERHGLTDAADEEEGEGEAGDRQTDILQLYISRPAIKMTNGDLNYLPQGGAGEGDMPSAGDMHSLSTHKEDIKQPNGGLLVADSTRPQGCACHRQCCSLSEAVPSPGTPPGSSPISSSSSSPVSARTVAGYFVSEEADRFRFLDVSRQSCRNTFEGSRRQSAPDHLADGLSLPAESPGTAEQDGDRPWKVGIAEFFSRNFFSKRTKDPKSSSSVPGWKLFGKVPPRETAQKDSKIIQQDDSSGSLSSVSTPNLLNTGEYEARTGRSCKAPSQSTRKKKFEFEPLSTTALILEDRPSNLPAKSVHETLRHRQEYDEMVAEAKKREVKEAQRRKKLMKERIRQEENIASAMVIWNTEILPNWDVMRSTRRVRDLWWQGLPPSIRGKVWSLAIGNELNITPELYEIFLSRAKERWKSFSETNSENENEDAGASLADREASLELIKLDISRTFPSLYIFQKGGPYHDLLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKPCQLAFFRVDHSMMLKYFAAFEVFFEENLPKLFFHFNAYSLTPDLYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTALGILRLYEDILLQMDFIHIAQFLTKLPEDITSEKLFGCIAAIQMQNSNKKWTQVFTSLMKDYKEGDKMSQASKT
What is the function of this protein?
May act as a GTPase-activating protein for Rab family protein(s).
What are the official names of this protein?
TBC1 domain family member 12.
Protein: HUTH_CALS4
Sequence: MKKVVIDGNNLTIEDVVKVARDKWEVVLSEVAKERIVHSREIVDRYVKEGKVVYGITTGFGKFSDVVISKEDTEALQKNLIMSHSCAVGDPLPEEVVRAIMLLRANALAKGFSGVRLETVETLIEMINKNVVPVIPEKGSLGASGDLAPLAHMVLVMIGRGEAFYAGERVSGEEAMRRAGIPTITLSSKEGLALINGTQVMSALGCLNVYDAKRIIAVADAVASITLEALRGIIDAFDDRVQMVRPHKGQIVSAKNVRKMVEGSELITRQGEIRVQDAYTLRCIPQVHGAVRDAISYIERVLGVEINSATDNPLIFPDDGEVISGGNFHGEPVALAMDFLSIALSEIANISERRIERLVNYQLNDLPPFLTEKGGLNSGMMIAQYTAASLVSENKVLSHPASVDSIPSSANQEDHVSMGTIAARKAREVLKNVTTVLAIELLTASQALEFRKGFKRGKGTDRIYRLVREKVNPLVEDRELYIDINACFDIIRSGRIEEVLKEEGIMLE
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PB2_I73A5
Sequence: MERIKELRNLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPSLRMKWMMAMKYPITADKRITEMVPERNEQGQTLWSKMSDAGSDRVMVSPLAVTWWNRNGPVTSTVHYPKVYKTYFDKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKEELQDCKISPLMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEVKNDDVDQSLIIAARNIVRRAAVSADPLASLLEMCHSTQIGGTRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSIKREEEVLTGNLQTLKIRVHEGYEEFTMVGKRATAILRKATRRLVQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEHIDNVMGMVGVLPDMTPSTEMSMRGIRVSKMGVDEYSSTERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTERLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQNPTMLYNKMEFEPFQSLVPKAIRGQYSGFVRTLFQQMRDVLGTFDTTQIIKLLPFAAAPPKQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKTTKRLTILGKDAGTLIEDPDESTSGVESAVLRGFLILGKEERRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.  In addition, participates in the inhibition of type I interferon induction through interaction with and inhibition of the host mitochondrial antiviral signaling protein MAVS.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host mitochondrion.
Protein: PUR5_STRPF
Sequence: MSEKNAYAKSGVDVEAGYEVVERIKKHVARTERAGVMGVLGGFGGMFDLSKTGVKEPVLVSGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPLYFLDYVATGKNNPVKLEEVVSGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAVGVAEKSQIIDGSKVKEGDILLGLASSGIHSNGYSLVRRVFADYTGKELLPELEGKQLKDVLLEPTRIYVKAALPLIKEELVNGIGHITGGGFIENIPRMFADDLAAEIDEDKVPVLPIFKALEKYGDIKHEEMFEIFNMGVGLMLAVSPENVNRVKELLDEPVYEIGRIIKKADDSVVIK
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GID1B_ARATH
Sequence: MAGGNEVNLNECKRIVPLNTWVLISNFKLAYKVLRRPDGSFNRDLAEFLDRKVPANSFPLDGVFSFDHVDSTTNLLTRIYQPASLLHQTRHGTLELTKPLSTTEIVPVLIFFHGGSFTHSSANSAIYDTFCRRLVTICGVVVVSVDYRRSPEHRYPCAYDDGWNALNWVKSRVWLQSGKDSNVYVYLAGDSSGGNIAHNVAVRATNEGVKVLGNILLHPMFGGQERTQSEKTLDGKYFVTIQDRDWYWRAYLPEGEDRDHPACNPFGPRGQSLKGVNFPKSLVVVAGLDLVQDWQLAYVDGLKKTGLEVNLLYLKQATIGFYFLPNNDHFHCLMEELNKFVHSIEDSQSKSSPVLLTP
What is the function of this protein?
Functions as soluble gibberellin (GA) receptor.  GA is an essential hormone that regulates growth and development in plants.  Binds with high affinity the biologically active gibberellin GA4, but has no affinity for the biologically inactive GAs.  In response to GA, interacts with specific DELLA proteins, known as repressors of GA-induced growth, and targets them for degradation via proteasome.  Seems to be required for GA signaling that controls root growth, seed germination and flower development.  May function as a dominant GA receptor at low GA concentrations in germination.  Partially redundant with GID1A and GID1C.
What are the official names of this protein?
Gibberellin receptor GID1B, AtCXE14, Carboxylesterase 14, GID1-like protein 2, Protein GA INSENSITIVE DWARF 1B, AtGID1B.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
What are the subcellular locations of this protein?
Nucleus.
Protein: T2R62_PANPA
Sequence: MPSLPTLIFIAIFCLESLAAMLQNGFLVTMLGREWVRCRMLSTSDMIVACLAASRFCLHGVAMANNLLASLDFSRAVPYMNIFWDLFNALTLWFTALLAAFYCVKISSFSHPTFAWLKWRISRLVPKLIKGSLIICGLEVISSATGNILFGQRKVSLSSYRNETLVYRVQASFQLYFFLYDGFVWSIPFLLFLVSTVLLIVSLCWQLGQMRDLRPGPCDPSTQAYTMALKSLTFSLIFCTLYFLSLFASALKIINFQNHWHWAWEVLIYANICLHSTVLVLRSPKLKKGLKTWPQLQCPCDAGSQGFGRCWP
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 62, T2R62.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CH15_DROGR
Sequence: MKFLIAFVAIAFFACVSAGGYGNIGLGGYGLGNVGYLQNHGGGYGRRPILISKSSNPSAAAAAAAASSGVNSGLYNQRGVIGYELDGGILGGHGGYGGGLGY
What is the function of this protein?
Chorion membrane (egg shell) protein; plays a role in protecting the egg from the environment.
What are the official names of this protein?
Chorion protein S15.
What is the protein family that this protein belongs to?
Belongs to the chorion protein S15/S18 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NUSB_PSEA6
Sequence: MKPAARRKARELAVQAVYSWQMSKNPLDQIELSIVTSNNMQDVDTEYFLELLRAVVRRTAELDAKIKPYLGRLPEELDPVENAILRLATYELVERIDVPYKVVINEAIELAKSFGAEESHKFVNGVLDKAIKTLRKHELS
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: ST7_DASNO
Sequence: MAEAGTGFLEQLKSCIVWSWTYLWTVWFFFVLFLVYILRVPLKINDNLSTVSMFLNTLTPKFYVALTGTSSLISGLILIFEWWYFRKYGTSFIEQVSVSHLRPLLGGVDNNSSNSSNSSNGDSDSNRQSVSECKVWRNPLNLFRGAEYNRYTWVTGREPLTYYDMNLSAQDHQTFFTCDSDHLRPADAIMQKAWRERNPQARISAAHEALEINEIRSRVEVPLIASSTIWEIKLLPKCATAYILLAEEEATTIAEAEKLFKQALKAGDGCYRRSQQLQHHGSQYEAQHRRDTNVLVYIKRRLAMCARRLGRTREAVKMMRDLMKEFPLLSMFNIHENLLEALLELQAYADVQAVLAKYDDISLPKSATICYTAALLKARAVSDKFSPEAASRRGLSTAEMNAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAIAYAFFHLAHWKRVEGALNLLHCTWEGTFRMIPYPLEKGHLFYPYPICTETADRELLPSFHEVSVYPKKELPFFILFTAGLCSFTAMLALLTHQFPELMGVFAKAMIDIFCSAEFRDWNCKSIFIRVEDELEIPPAPQSQHFQN
What are the official names of this protein?
Suppressor of tumorigenicity 7 protein.
What is the protein family that this protein belongs to?
Belongs to the ST7 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS17_BORPD
Sequence: MSETQNTQTKRQRTLVGKVVSNKMDKTVVVLVERRVKHPIYGKIVMRSAKYKAHDESNQYNEGDTVEIAEGRPISRSKSWNVVRLVEAVRII
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: DNBI_BHV2B
Sequence: MENKQKTATTVKVSPGPLGYVYARRLPPEGLTELALLSARSADSDTAVLPLIAGLTVESGFDVNVAVVVGSRTTGVGGTGVSLKLMPSHYAPSAYVFHGGRHLAPSSAAPNLSLLCDRARVQFGFSSFKPKPCEAEGETTGEALCEHLGLNPNESLLYMVIAEGFKEAVYISNTILHMGGVGTVTIAGEEVRRIPIYPLQMFMPDYCRAVADPFNDRHRAIGEYFAYPLPFFNAKLASLLFGAAVGPAAVALRARNVDAVARAAAHLAFDENHEGAALPADITFTAFDPTGSKAGHRNPRECGGGFEQRLASVMAGDAALALESIMSMAVFEEPPTDIGTWPMLTCQESTAARAASIGAYLGRAAGLVGAMVFSSNSALHLTEVDDAGPADPKDPTKPSFYRFFLVPGTYVAANPQLDRDGRVVAGHEGRPIVPIVGGNHEFTCEHLATLCGFSPELLAKMLYYLERCDGGVILGRPEMDTFKYVSDSAHTDVPCCLCSLDNRHSCAHTTLLRLRARHPKFTSTTRGAIGIFGVMNSAYSDCDVLGNYASFSAIKRMDVQETARAIMQETYRSAVERVMAELENLNYIDAAVPTSPAKLESIITGREALQTVVSNVKQVVDGEVAQLMRALVEGRGFRFREALGEANHAMSLTLDPHASVPCPLLQMLGRRSNLAVYQDLALSQCHGVFEGQAVEGRNFRSQFQPVLRRRVLDMFNNGFLSARTLTVALTDGACISAPGLVSGQHAAAESGFEGDVARVNLGFPKEIRVKSRVLFAGAGPAASEAARARIAGLQSAYQKSDKRVDILLGPLGFMLKQFHATLFPNGKPPGSDNPNPQWFWTALQRNQLPARLLSREDISLIAFVKRFSVEYGAGNFVNLPPNNISELAMYYMANQILKYCDHSTYFINTLTALIAGSRRPPNAQAAAAWAPRGGTELEAQARSVVANPGDHPGAWTTMFASCNLLRPVMATRPMVVLGLSISKYYGMAGNDRVFQAGNLANLLGGKNACPLLIFDRTRKFVIACPRAGFVCAAVSAGSGAHESSLCEQLRAIIAEGGATVASDVFAAAAKSLGARVQQLQIEDWLALLEDEYLSEEMMELAGRALERGGGEWSLDAALDVAREAEAMVTRHVDAEETFDFGAFAEDGPADAGLAVHLQSRRRPLACSDLFGDAPAEKRNDLTLDML
What is the function of this protein?
Plays several crucial roles in viral infection.  Participates in the opening of the viral DNA origin to initiate replication by interacting with the origin-binding protein.  May disrupt loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation.  Promotes viral DNA recombination by performing strand-transfer, characterized by the ability to transfer a DNA strand from a linear duplex to a complementary single-stranded DNA circle.  Can also catalyze the renaturation of complementary single strands.  Additionally, reorganizes the host cell nucleus, leading to the formation of prereplicative sites and replication compartments.  This process is driven by the protein which can form double-helical filaments in the absence of DNA.
What are the official names of this protein?
Major DNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae major DNA-binding protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=In the absence of DNA replication, found in the nuclear framework- associated structures (prereplicative sites). As viral DNA replication proceeds, it migrates to globular intranuclear structures (replication compartments).
Protein: RL19A_SCHPO
Sequence: MANLRTQKRLAASVLKCGKRKVWMDPNEISEISNANSRQNVRKLIKDGLVIRKPNLMHSRFRIRKTHAAKRLGRHTGYGKRKGTAEARMPSAVVWMRRQRVLRRLLRKYRESGKIDKHLYHTLYLEAKGNTFKHKRALIEHIQRAKAEANRTKLIQEQQDARRARAKAARQRRAKAVEEKREQLYTAAEKIEE
What are the official names of this protein?
60S ribosomal protein L19-A, YL15.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL19 family.
Protein: CIPK5_ORYSJ
Sequence: MEKKASILMNRYELGRMLGQGTFAKVYHARNLASNQSVAIKVIDKEKVLRVGMIDQIKREISIMRLVRHPNIVQLHEVMASKSKIYFAMEYVRGGELFSRVARGRLKEDAARKYFQQLIGAVDFCHSRGVYHRDLKPENLLVDENGNLKVSDFGLSAFKECQKQDGLLHTTCGTPAYVAPEIINKRGYDGAKADIWSCGVILFVLLAGYLPFHDSNLMEMYRKISKGDVKFPQWFTTDVRRLLSRLLDPNPNIRITVEKLVEHPWFKKGYKPAVMLSQPNESNNLKDVHTAFSADHKDNEGKAKEPASSLKPVSLNAFDIISLSKGFDLSGLFENDKEQKADSRFMTQKPASAIVSKLEQIAETESFKVKKQDGLVKLQGSKEGRKGQLAIDAEIFEVTPSFFVVEVKKSAGDTLEYEKFCNKGLRPSLRDICWDGQSEHPSLAQSSTLTQSSKSISRHAI
What is the function of this protein?
CIPK serine-threonine protein kinases interact with CBL proteins.  Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity).
What are the official names of this protein?
CBL-interacting protein kinase 5, OsCIPK05.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Protein: YCF53_PORPU
Sequence: MKNQIQVQLSKLKETSNSENAIKKQLEIIETIEYNDYLQLKKLAEIFHYRITKPEYISNCVDGLIYEKLLNSQNSEIIKFTSKLCPKGIVPLKSNKQMDYQDLQILLVQNNLIAADKLTQQKLIKLAGVDEKSRNWLYFTDIKKIPVEDLQTIDQLWNAHSKGKFGFFVQRQIWLALEKNWEQFWYKIGWEINRVPCRYPEEFHWNSTGPKGHLPLCNQLRGVQVLSALFSHKAWDNY
What are the official names of this protein?
Uncharacterized protein ycf53, ORF238.
What is the protein family that this protein belongs to?
Belongs to the ycf53 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MTNC_HAHCH
Sequence: MAEFNGIRAIVTDIEGTTSSISFVHEVLFPYAAKHMDAFIRENFSAPAVAEQLDEVARLGGVDRKSPDALIKQLLDWIAEDKKITPLKALQGMIWRSGYDEGAYKGHVYPEVAERLRHWRELGIRLFVYSSGSVAAQKQIFGFSEAGDLTPLFSGYFDTRVGGKRDADSYRAIVREVSEPASSVLFLSDVPAELSAAAEAELQVCQLVRGAGIERQETYPAVASFADLLIKPA
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: RAD50_NANEQ
Sequence: MVIVKKVILNNVKTHSKREFDFEKGINLILGPNGSGKTTLVESIFLALFGGDFARVIDYFKKGEKTMAITLILEDKGKTYRIRRKWVLENNAKLVESSLELIDTIPKKLASDHNKLLQQIKHLFGLDKKIIPLIYYKQNEITKIIEMDPRKRKEWFDEILGIKDLEEFSEKLKMAIKLIKTGKISRIEDRIKLLKAELNKKSLLENKLKNYKEKLVLLSNELENLEKEYKILENQYKEYLELKAKLKSIEGQINNINVKEIESKINNIREELNNIEELTDYEKDILSKKHEIIRCNEIKNRLKELEKEIKDYDKIKKEFLEIESKYKQYEEKRLEYEKAKMLEKEKEKAKREYSYLLKEKESLEKEIAELQNKINQIKELEKMEQELLEIQERIGVIKAKLKLLENIKDRCPLCGAKLSSDTIEHLQKEREKLQKEYYYLKEKYNQLLIKIRALEKYKGLEKVLEAKTKHLETIENRLKEIKPIIELEIPKIELDESIPYKYKQLLNKVSYLEAKIKEYERYKNIECPYDIAIEELKRIEDKYNKYIKKPALERELNLLLKELERYNSLLKEKEEILSKLNPEIETKYKELTKKKENLLSEISKVKGIIKEIESQIKEIEKHESTIKQLEEKKRKWEKLVEKLNRIVKALGRDGIPKALREGAINYINDMANIYLREFTDKYKLKVNNDLSIYAIPIDNPHYEIEAKNLSGGEKVVFSLSIALAIISWLSLQNMFMVLDEPTANLDNERTLALRKTFDKLEKMVEQAIIVTHNELLDTGENHVVRL
What is the function of this protein?
Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair.  The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA.  Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
What are the official names of this protein?
DNA double-strand break repair Rad50 ATPase.
What is the protein family that this protein belongs to?
Belongs to the SMC family. RAD50 subfamily.
Protein: CC187_MOUSE
Sequence: MTTPLMGVMPTSLRATLQNCSRGNQQEGLFSPKAMGRMAGQKDSTKPRDEVFHPHAAKDSLLATTLRWPVLSQQLSPPQTVPYVAWSGNIKDPSPYMKGCSLPMWSPCLDTKDVDSSVSSGRMSGSSGGHESCTLSHGPWKERPPLILGPQRQPRKSDPRLEQLRDKIRAQAQWQASCASLGTSAPSSASCLYKTSTMLWRKTPKVTNALPVPAFPGSGVLRTAEHRGKDRASLSLRRELSKVPQHHTSVPRTNFKKVKNASCKREISKSSILRRTAKGRGSDRKAAAVKASPAHTWLCKPMSAHSDQQVSKHTPSLAFQDQSATIHGAMETLQDLRQQIQAGLELTRSPRVDRKLSLSKPKPQNLVGKRDRGLQSTQDMQGSSKTAWTVTEGKNSSLHRAGNLHSQQHRKKALAEHESCPRRTWTGQGQDSSFPRPGSTPEKPRFFSQRPWSALARQTYPQRTWDAQGQDISVQKSGSSLKKPSPFSQRPWSALAGRAYSACEDREVFEPSPWNSLSRPHSALQDPWSNSFVQRSSPSSKGKSAVPPPSKVKPAWPEPSQDLLQSKPAKEQDTPCPRPRGSLGQQHSSESLRDFMRQKAQARRQQALEQKALAAHTLELRNQRLQEVYRKQREAVLGKDIPVVSQRRPGIVTFVPMQSGGMEAPGSLGSPREQTWSKVTSGMVLGDQEAPDSFCLCLNKPWNRIETQDTGRPLEGYKQARLQALETMAEALRQRVDILTTKLDKPTSPDTSGDLASDVLPLCPSTAPATPTLVPPSYLRTLMSKGGRESPRDLVDSQAEPLLLSTCFQDGEMLPWSPSWELPNPNLGTHIESQPQGPVSSTPASVSQVIPHTQSCPAGSSSHGALSKEAIQGLEKKLQREMATLQALGACMKSSLGMPDAPDPTRGSLWQEEMPEVKKEGLVTPWTTRSCGKGEPADRPWAGWSGGQGGLPWASSTA
What are the official names of this protein?
Coiled-coil domain-containing protein 187.