PharMolix/UniProtQA huggingface dataset:
Protein: OTC_CAMC5
Sequence: MRHFLTLDDFSKDEILQMINLAGKIKKEAKVREFKPYLKDQTLAMIFEKSSTRTRVSFEVGMYQLGGHALFLSANDLQIGRGEPIKDTARVISSMCDMAMLRVNRHETLEEFAKFSQNPVINGLSDKFHPVQLMADYLTMRERGSGEKIAYIGDGNNMAHSWLMLASKLGLELRIATPKGYEPDAKILEKAQQNAKISGAKIYLSNEPKEAVSGADVVTTDTWVSMGQEAQKEKRLREFAGFCVDENLMSLAAKNAIFLHCLPAYRGYEVSEAVFEAHADEIFAEAQNRLHAQKGVMVWLNDKR
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_BURMA
Sequence: MKLHIVAVGHKMPGWIASGFDEYAKRMPPELRIELREVKPELRSGSRTADSVMAAEQQRIEAALPKNARVVALDERGRDWTTMQLAQALPAWQQDGRDVAFVIGGADGLAPALKSRAELLLRVSSLTLPHGMVRVLLAEQLYRAWSITQNHPYHRA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRC_ECO81
Sequence: MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: RECO_CUPPJ
Sequence: MPDFARGPAKARRADPVVDEAAELLDSRALPGMADAAGRAMMDRAMRIVPARSETRVSEQPGFVLHAWPYRETSLILDVFTRDHGRLSMVAKGAKRPHSALRPVLQHFHPISLSWSGRGEVKTLTRAEWVGGMPPLAGDALLSAFYLNELLMRFCPREDGHPALFRHYMATLTRLAHGEAAGLVLRSFERVLLQETGFAVAFDQCLSTGERVQPHLDYVYQPERGVRRAQPSDPSSWPVVSGQTLLDMSQDDYGRAQTALQSRALMRFLLHYYLQGAPLKTRQILIDLHYL
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: SYI_PASMU
Sequence: MTVDYKNTLNLPETGFPMRGDLAKREPNMLKSWYEKDLYQKIRQASKGKKSFILHDGPPYANGTIHIGHAVNKILKDIIVKSKTALGYDSPYIPGWDCHGLPIELKVEGLVGKPNQNISAAQFREACRQYAAEQVEGQKKDFIRLGVLGDWDNPYLTMNYHTEANIIRAFGKAVENGHLYKGSKPVHWCLDCASSLAEAEVEYEDKVSPSIYVRFSAVDSDAVLAKFNATDKGTGNISAVIWTTTPWTIPSNRAIAIHENLDYQLVQFNDERVILAKDLVEEVAKAAGVEQVVILGESKGKDLEWLRFQHPFYDFSVPFILGDHVTTDGGTGLVHTAPDHGHDDYIIAQKNGIEMAGLIGNDGLFKADVPFFAGKGVFESNDLVVAKLQEVGAMLKFSKIKHSYPHCWRHKTPIIFRATPQWFIGMEKQGLRQQALSEIKKVRWIPDWGQARIEKMVENRPDWCISRQRTWGVPVALFIHKETEELHPRTVELVEEVAKRVEQKGIQAWWDLDTAELLGADADNYIKVPDTLDVWFDSGSTYYSVVKDRPEFNGQEADMYLEGSDQHRGWFMSSLMLSTATDNKAPYKQVLTHGFTVDGQGRKMSKSIGNIVTPQEVMDKFGGDILRLWVASTDYTGEISVSDEILKRAADAYRRIRNTARFLLANLNGFDPKRDLVKPEEMMVLDRWAVDCAYQAQNEIKDAYDNYQFHAVIQRLMKFCSIEMGSFYLDIIKDRQYTTKADSLARRSCQTALWHIAEALVRWIAPVLSFTADEIWQYIPGERGEFVFTEEFYNGLFALDANEQMNDAYWQQVITLRNEVNRVLEQARNDKIIGAALEAELTIYANDTYAPLLAKLQNELRFVLLTSKAEVKPLADADVAEGEVKGFAVKVVRSANHKCPRCWHYSDSKDAESLCSRCDENVNGQGEVRQFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_FRATN
Sequence: MFSFEKNSLKNTDKEIFDAIELEVKRQHEHVELIASENYASPAVMEAQGSQLTNKYAEGYHGKRYYGGCEFVDIAEKLAIERAQQLFGVDYANVQPHSGSQANAAVYNAVLKPGDTVLGMDLGAGGHLTHGSKVNFSGKIYNSIQYGLDENGDIDYEQVAQLAKEHKPKMIIAGFSAFSGIINWQKFREIADSVDAVLMADIAHVAGLVAAGVYPNPFPYVDVATTTTHKTLRGPRGGLILCNNNPELAKKFQSAIFPGIQGGPLMHVIAAKAVAFKEALEPSFVDYQKQVLKNAKAMEKVLKQRGINIISGGTSNHLLLLDITNTGFSGKEAEAALGRANITVNKNSIPNDPRSPFVTSGLRIGSPAITTRGFKEKECELVANLLADVVFNCGDEKVENETAAKILDLCDKFPVYK
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_TROWT
Sequence: MQLSGYPMRQASCDMKEGGLRNKVAVIGSGSWGTAIANLLCKAGNETILWGRDENVIDEINNARVNSKYLPGVELFLRATCDLDYAVADASHVYIALPSFALSKVLPKLSLDKFSIVISLIKCLEPDTGRRMSEVISEALDLGHNRLAVISGPNLALEVANDEPSVSVVASANIATANIVAGTLKCPGFYCIPSSDIKGVEICAASKNLVALISGIARGMDLGDNTRAALITLGFRELLRLVLENGGTEETVFGVAGLGDVVATCNSHLSRNNKAGVLLAKGAPLDEVKQTAEGVVAISGVLALAERSGVYMPIAQALSQVISGKRTAHSLLDICFSLA
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRS1_NEOFI
Sequence: MAPNATTKKRAAAKDDDFVLTLSDDENDVLENGVEEDTLSSSKKRKRDAAEAPKGKNKKQKQLKKSKKGESAAGAVSDDQSGEEDEAEAMDAGEDDGALDSEFEFDVGGNANTGVIEGFDGWEARNGAGPADAPKNGDKKAVDIDDIISRRKAKKEAELKKKQQKEKKRREEEGEEESEDEDADSDGGMSVDFQDDELLAADGFGMGADGADESGDDVENDSNDSDDADEKGSEDEESDDDAAASDNDSVATPVHHPDDEAASDEESEAESEVDAEEAEKRKAFFAPEEKSTAASTSNRSFQDFNLSRPILRGLASVNFTTPTPIQQKTIPVALLGKDIVGSAVTGSGKTAAFVVPILERLLFRPRKVPTSRVAILMPTRELAVQCYNVATKLATHTDITFCQLVGGFSLREQENILKKRPDVIIATPGRFIDHMRNSPSFTVDTLEILVLDEADRMLEDGFADELNEILTTIPQSRQTMLFSATMTDSVDKLIRVGLNRPVRLMVDSKKNTSMNLTQEFVRLRPGREDKRLGYLLYLCNEIYTGRVIVFFRQKREAHRVRIVFGLLGLKAAELHGSMSQEQRIKSVENFREGKVAFLLATDLASRGLDIKGVETVINYEAPQSHEIYLHRVGRTARAGRSGRACTIAAEPDRKIVKSAVKAGKAQGAKIVSRVVDPAVADEWAAKAKGLEDEIEEVLQEEKLEKQMAQAEMQVTKGENMIKHEAEIMSRPKRTWFETERDKRAARKLGATELNGPSKKDKVKLSNKDKKRLDDARQRHEGNIGWKKGKADREAPKQGKNKGSKNKSDKKNNIKMKGKK
What is the function of this protein?
ATP-binding RNA helicase involved in ribosome assembly.
What are the official names of this protein?
ATP-dependent RNA helicase drs1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX27/DRS1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ACHG_TETCF
Sequence: MVLTLLLIICLALEVRSENEEGRLIEKLLGDYDKRIIPAKTLDHIIDVTLKLTLTNLISLNEKEEALTTNVWIEIQWNDYRLSWNTSEYEGIDLVRIPSELLWLPDVVLENNVDGQFEVAYYANVLVYNDGSMYWLPPAIYRSTCPIAVTYFPFDWQNCSLVFRSQTYNAHEVNLQLSAEEGEAVEWIHIDPEDFTENGEWTIRHRPAKKNYNWQLTKDDTDFQEIIFFLIIQRKPLFYIINIIAPCVLISSLVVLVYFLPAQAGGQKCTLSISVLLAQTIFLFLIAQKVPETSLNVPLIGKYLIFVMFVSMLIVMNCVIVLNVSLRTPNTHSLSEKIKHLFLGFLPKYLGMQLEPSEETPEKPQPRRRSSFGIMIKAEEYILKKPRSELMFEEQKDRHGLKRVNKMTSDIDIGTTVDLYKDLANFAPEIKSCVEACNFIAKSTKEQNDSGSENENWVLIGKVIDKACFWIALLLFSIGTLAIFLTGHFNQVPEFPFPGDPRKYVP
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Acetylcholine receptor subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Gamma/CHRNG sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: PYL3_ARATH
Sequence: MNLAPIHDPSSSSTTTTSSSTPYGLTKDEFSTLDSIIRTHHTFPRSPNTCTSLIAHRVDAPAHAIWRFVRDFANPNKYKHFIKSCTIRVNGNGIKEIKVGTIREVSVVSGLPASTSVEILEVLDEEKRILSFRVLGGEHRLNNYRSVTSVNEFVVLEKDKKKRVYSVVLESYIVDIPQGNTEEDTRMFVDTVVKSNLQNLAVISTASPT
What is the function of this protein?
Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition.  Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA (PubMed:22579247, PubMed:23844015, PubMed:21658606).  Can be activated by both (-)-ABA and (+)-ABA (PubMed:23844015).
What are the official names of this protein?
Abscisic acid receptor PYL3, PYR1-like protein 3, Regulatory components of ABA receptor 13.
What is the protein family that this protein belongs to?
Belongs to the PYR/PYL/RCAR abscisic acid intracellular receptor family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane. Note=Localizes at the plasma membrane in the presence of a CAR protein.
Protein: GHSR_RAT
Sequence: MWNATPSEEPEPNVTLDLDWDASPGNDSLPDELLPLFPAPLLAGVTATCVALFVVGISGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVILVIWAVAFCSAGPIFVLVGVEHENGTDPRDTNECRATEFAVRSGLLTVMVWVSSVFFFLPVFCLTVLYSLIGRKLWRRRGDAAVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFKLLGFESFSQRKLSTLKDESSRAWTKSSINT
What is the function of this protein?
Receptor for ghrelin, coupled to G-alpha-11 proteins.  Stimulates growth hormone secretion.  Binds also other growth hormone releasing peptides (GHRP) (e. g.  Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e. g.  L-692,429, MK-0677, adenosine) (By similarity).
What are the official names of this protein?
Growth hormone secretagogue receptor type 1, GHS-R, GH-releasing peptide receptor, GHRP, Ghrelin receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KSB_CUCMA
Sequence: MYLSRPTGVARFAASSSSSSSASLFPGVDVDTTTKTGALHFEETKERIKKLFDKVELSVSAYDTAWVAMVPSPNSLNQPLFPECINWVLDSQHADGSWGLLHNDQLLMKANLLSTLACVLTLKRWNIGHDHMSKALDFIKSNIASATDENQRSPVGFDIIFPGMIEYAKDLNLNLPLAPTNVDALVRKKELELRSCRSNSEGGKAYLAYVSEGIGKLQDWDMVMQYQRKNGSLFNSPSTTAAAFMHRNDDGCFDYLRSLLQKFDGSVPTIYPLDIYARLHMVDSLQKFGIARHFKEEIRSVLDETYRCWMQGEENIFLDASTCAMAFRMLRVEGYDVSSDQLTQFSEDIFPNCLGGYLKDFGASLELYKASQIITHPDESVLENINSWTSRFLKHGLSSDSVWSDRTDSVVKQEAVNALEFPYNATLERLISKRAMESYSGDIVRISKSPYACLNFGHQDFLELAVEDFNTLQRIHLKELEELQRWVVENKLDELKFFRLHLGYCYFAAAATLTDPELHDARIAWAQNGVLTTVVDDFYDGGGSEEELDNLIELVEKWDPDGEVGYCSKDVEIVFLALHSTVCEIGRRALVWQGRSVMRNVIDGWLALLKVMRKEAEWSTNKVVPSMGEYMEQAHVSFALGPIILPMLFFVGPKLSEEMIGSCEYQKLYKLMSTAGRLKNDIRSYDRECKEGKLNILSLWMIDGGGNVTKEEAIEAIKGDFERAIRELLGLVLQENTTIPRACKDLFWKLMSIVNLFYMEDDGYTSNRLMNTVKAMFEQPMDLDALLNK
What is the function of this protein?
Catalyzes the conversion of ent-copalyl diphosphate to the gibberellin precursor ent-kaur-16-ene.
What are the official names of this protein?
Ent-kaur-16-ene synthase, chloroplastic, Ent-kaurene synthase, Ent-kaurene synthase B, KSB.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GLOD5_MOUSE
Sequence: MCDPTSESQLWRSSSQIPSPCLICRLDHIVMTVKNIEDTTMFYSKILGMEVTTFKGNRKALCFGDQKFNLHEVGKEFDPKAAHPVPGSLDVCLITEAPLEEVIERLKAFDVPIEEGPVFRTGAKGPILSIYFRDPDRNLLEVSSYVTS
What are the official names of this protein?
Glyoxalase domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the glyoxalase I family.
Protein: GRPE_PARTM
Sequence: MEKERDVAQEQATYEQESPNAERQEELKENEHQEKNAPEEQEKVREENGRQDAQKDEIGDPEKAKEEQNEELAAANAKIAELEAKIKEMENRYLRLYADFENFRRRTRREMEAAEKYRAQSLVSDLLPVLDNFERALKIKAEDEQAKSILQGMEMVYRSVLDALKKEGVEAIEAVGKPFDPHLHQAVMQVEDSNYEPNTVVEELQKGYKLKDRVIRPAMVKVSQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KRA71_MOUSE
Sequence: MTRYFCCGNYFPGYPCYGTNFHGTYRATPLNCVVPLGSPLNHGCGTMYSSRNFCYGGISNFSNPGCCYGSSLYRPWGSGSGFGYSTY
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 7-1, High glycine-tyrosine keratin-associated protein 7.1.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 7 family.
Protein: KDPB_LEPIC
Sequence: MNRESKVFIESPILKEAILNTFKKLHPFLQAKNPVMFIVFLGALFTTWIFFKDLYYGVYSSFNLQISLWLWFTVLFANFAEAIAEGRGKARTDSLKKTRSNIIAKKLVGNKIENVPGTLLKIGDIVICEAGDLISGDGEILEGIASVDESAITGESAPVVRESGGDRSAVTGGTKVLSDRIKISITAEQGRTFLDQMIALVEGAKRQKTPNEIALTMLLSGLSFIFLIAVMSLPLFAEFVAKEGGQSANLSIPILISLLVCLIPTTIAGLLSAIGISGMERLIRFNVISKSGRAIEAAGDIDILLLDKTGTITLGNREARDFYPAKGVDEKYLADVAQLSSLADETPEGRSIVILAKDKFGIRERNLSEMEGEFIPFSASTKMSGVNLKKEGKVVRKIRKGAGDSIRNYLHTLGQKISAELEETIQTISQRGSTPILITEEDRLLGVIELKDIVKGGLKERFASLRKMGIRTVMITGDNPLTAAAIAAEAGVDDFLAEATPETKLKKIREQQAKGYLVAMIGDGTNDAPALAQSDVGVAMNTGTQTAREAGNMIDLDSNPSKLIEIVEIGKQLLMTRGALTTFSIANDVAKYFAILPALFGSFYAVSEVGPLSALNLMKLGSQKSAVLSAVIFNALVIPALIPLALRGIVYKPLGADRILKRNLLIFGLGGMVIPFLGIKCIDLMLGFLGII
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYY_LEVBR
Sequence: MNIIDELTWRGAINQQTDAEGLKKLTSEKKISLYCGVDPTGDSMHIGHLIPFMMMKRFELAGHHPYILIGGATGSIGDPSGRKTERQLQTMDKVQHNVKALSRQMQRLFGGDSNVTMVNNYDWLSKISLLDFLRDYGKLVNINTMLAKDIVASRLDTGISFTEFTYQILQSVDFLTLHNDHNIQLQIGGADQWGNITAGIDLIHKIKGADEAVYGLTIPLMLKADGTKFGKTAGGAIWLDADKTSPYEFYQFWLNQDDRDVIRYLKFFTFLGQDEINQLAAAVEDEPEKRLAQRRLAEEVTRFVHGEEALESAQHISEILFSGDIQRLTLTEVQEAFEKVPNVSINSEPTNIVELLTETAIEPSRRQAREDITNGAITINGERCTDTDAQLNPKTNFSGKFMVIRRGKKNYFLAKVKD
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URK_STRP2
Sequence: MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYKDQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQEPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQYLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECB_BUCBP
Sequence: MITTIPKSINVTTIPLSGKILIEASAGTGKTFSLTILYIRLLLGITNHVKYKKGLLIKEILVVTFTEHTRAELEIRIKTYIKIFKTACIKKYSNNYVLSKLLSKITDFPKTIDILSKAENSIHELSIYTIHGFCYKILKLNKFNSELMLQNKILKHTYPLYLKISIKFWKYYFAFLSLDITSILLEYFNNPKTLLKEILPLLNKTQLISKLTKTKRKNIVQEYYILIKKIKLFKQKWANYSHLIHSEIIKTNVNKRIYTKSNLKRWINNITAWATQKQTKNFFIPSELKYFRYSFIIKKTTSEKILDDKFFKFIDTFLDSKFSLKEIFIIDASLEIKAMFMQEKIKNRYFEYDDLITFCWNMVNKNNFNISQTILKKYPVALIDEFQDTNNKQYNIFKKIYKKENLLILISDPKQAIYSFSGADITSYLQAKSNIKNQYFLDTNWRSSPKIINSINLLFSRLKNPFLTKNITFYPVKSSRINKTTKFEVNGKNQPALRFLLNKNKNISINEYKEWISITTAKYISYWISSGIKGNATITISNKVRTVNFSDIAIIVRNNLEAKTIQLELTKLNIQSLYLTSKNNIFQSKEILEILWILQAILNPNIERLLKRAMSTNIMSKNTKEIISIPNNHSYWIKLSQEFNQYLIFWNNYGILYVIQQLIINYNISNNNNLLHNFSPNIKNILYIGELLEEKSITIKNKFLLINWLKKNITQDFYLTKPKYIKPNYEKNNYIKIVSIHKSKGLEYPITIIPFATITFNKTVSTVEKICFNLNNTKIKKQKTLKIEKHKFSEDIRLLYVALTRSIIHCSIGISLAQTITQKKKIQKEKSKFKINVLRYIIQSGKNHISTKKLYTELSILKKNKNIEIISEIPNIIKKNFQIPTLNTNSQSLMHYQVSRKFNYNYNFTSYSQLKKNIKPSTMYSTLNTKKLFELNVKKKHCFENKILTPHTFPSGKIYGTLLHKILKNISFHKSINSNWLLKKLSEYNLDKRWCLILKNWMYSILYKNLDKNYNLRLSKLDSKNYIKELKFLLPIKKKLTALKLNNIFQTHQCSSLENKLCFHPIQGILSGSIDLVFLWKTKYFLVDYKSNWIGNSNQSYSQQNIKKIIKKHHYNFQLQLYSLVLHRYLKQHIKNYSFYNHFGGTYILFIRSINEIPSQNGIFYSIPNIEIIKKLEQIF
What is the function of this protein?
A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair.  Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity.  Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction.  Cuts ssDNA a few nucleotides 3' to the Chi site.  The properties and activities of the enzyme are changed at Chi.  The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair.  Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination.  In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
What are the official names of this protein?
RecBCD enzyme subunit RecB, Exonuclease V subunit RecB, ExoV subunit RecB, Helicase/nuclease RecBCD subunit RecB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. UvrD subfamily.
Protein: DPO4_VIBPA
Sequence: MSERIRKIIHVDMDCFYAAVEMRDNPNYRDIALAVGGHEKQRGVISTCNYEARKFGVRSAMPTARALQLCPHLLVVPGRMHIYKQVSLQIRAIFERYTSLIEPLSLDEAYLDVTDATACRGSATLIAESIRNDIRNELGLTASAGIAPIKFLAKVASDMNKPNGQFVIPPEKVQEVVDKLPLEKIPGVGKVSLEKLHQAGFYLCEDIKNSDYRELLRQFGRQGASLWKRSHGIDDREVVVERERKSVGVERTFSQNISTYDECWQVIEEKLYPELEKRLERASPDKSIIKQGIKVKFADFQLTTIEHIHPQLELEDFKLLLKDILKRQNGREIRLLGLSVMLKPEEQARQLSFF
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO2_MACFA
Sequence: MVLGRGLLGRRSLAALGAACARRGLGPALLGVLHHTDLRKNLTVDEGTMKVEVLPALTDNYMYLVIDDETKEAAIVDPVQPQKVLDAARKHGVKLTTVLTTHHHWDHAGGNEKLVKLQSGLKVYGGDDRIGALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFVSRPGGSEPPAVFTGDTLFVAGCGKFYEGTADEMCKALLEVLGRLPPDTRVYCGHEYTINNLKFARHVEPGNAAIQEKLAWAKEKYSIGEPTVPSTLAEEFTYNPFMRVREKTVQQHARETDPVTTMRAVRKEKDEFKMPRD
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, mitochondrial, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
What are the subcellular locations of this protein?
[Isoform 1]: Mitochondrion matrix. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
Protein: CA162_MOUSE
Sequence: MGSTSSTPKSTICTFSTTAPVTSSTPYFFNPKKEHIILAFFAGVLLTLLIVALIFLIVKSCRKCHSSAQTQDPPSEPPTKLSSLSKESLTYASMTFKPPEENSNDLTRNHSSGLEPTIYSQIKVTDSDLPLP
What are the official names of this protein?
Transmembrane protein C1orf162 homolog.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RISB_SHEB8
Sequence: MNVVQGNIEAKNAKVAIVISRFNSFLVESLLEGALDTLKRFGQVSDDNITVVRVPGAVELPLAARRVAASGKFDGIIALGAVIRGGTPHFDFVAGECNKGLAQVALEFDLPVAFGVLTTDTIEQAIERSGTKAGNKGGEAALSLLEMVNVLQELEQQLL
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.