PharMolix/UniProtQA huggingface dataset:
Protein: MDEP_STAAW
Sequence: MIVNYLKHKFYNLLTTMVVLFIFVLSGAIFLTFLGFGLYGLSRILIYFRLGDFTYNRSMYDNLLYYGSYIIFGYFIIFAVEHLMDYFRKMLPENAYFRGATFHLISYTVATTLFYFIIHLNYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK
What is the function of this protein?
Involved in multidrug efflux.
What are the official names of this protein?
Multidrug resistance efflux pump SepA, Antiseptic resistance protein SepA, Staphylococcal efflux pump A.
What is the protein family that this protein belongs to?
Belongs to the multidrug resistance efflux pump SepA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TYW31_PYRHO
Sequence: MRFTENFERAKKEALMSLEIALRKGEVDEDIIPLLKKINSIENYFTTSSCSGRISVMEMPHFGDKVNAKWLGKWHREVSLYEVLEAIKKHRSGQLWFLVRSPILHVGAKTLEDAVKLVNLAVSCGFKYSNIKSISNKKLIVEIRSTERMDVLLGENGEIFVGEEYLNKIVEIANDQMRRFKEKLKRLESKINALNR
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway.  Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.
What are the official names of this protein?
tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase 1, tRNA wyosine derivatives biosynthesis protein Taw3 1.
What is the protein family that this protein belongs to?
Belongs to the TYW3 family.
Protein: DHA_GEOSE
Sequence: MKIGIPKEIKNNENRVAITPAGVMTLVKAGHEVYVETEGGAGSGFSDSEYEKAGAADRCRTWRDAWTAEMVLKVKEPLAREFRYFRPGLILFTYLHLAAAERVTKAVVEQKVVGIAYETVQLANGSLPLLTPMSEVAGRMSVQVGAQFLEKPHGGKGILLGGVPGVRRGKVTIIGGGTAGTNAAKIGVGLGADVTILDINAERLRELDDLFGDHVTTLMSNSYHIAECVRESDLVVGAVLIPGAKAKLVTEEMVRSMTPGSVLVDIAIDQGGIFETTDRVTTHDDPTYVKHGVVHYAVANMPGAVPRTSTFALTNVTIPYALQIANKGYRAGCLDNPALLKGINTLDGHIVYEAVAAAHNMPYTDVHSLLHG
What is the function of this protein?
Catalyzes the reversible reductive amination of pyruvate to L-alanine (Probable).  A key factor in the assimilation of L-alanine as an energy source via the tricarboxylic acid cycle during sporulation (By similarity).
What are the official names of this protein?
Alanine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the AlaDH/PNT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNA_XANOP
Sequence: MNDSAHIDYARYDHIRPLLWTGDALELLDQRKLPFVVEHVRCDTSDAVAEAIHSLAVRGAPAIGIAAGWGVALAARDIAADDGNAALQKLEPALLRLNAARPTAVNLAWALMRMRRVLGAAGADWRAVIAREAQAIADEDLAANRHMGALGAALIAPGSGVLTHCNTGSLATAGFGTALGVIRAGMAQQRIAKVFAGETRPWLQGARLTVWELQQDGIDATLIADSAASHLMKSGLVQWVIVGADRICANGDTANKIGTYQLAIAARHHGVKFMVVAPSSTVDMATASGDQIEIEQRDPGELFGVGGVRTVADGIHAWNPVFDVTPGDLIDAIVTERGVIAQPDQARMQAAFGN
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: END4_BACLD
Sequence: MLKIGSHVSMSGKHMLLAASQEASSYGANTFMIYTGAPQNTRRKKIEDLNIEAGRAHMEENGISDIVVHAPYIINIANTTNPATFELGVEFLRSEIERTSAIGARQIVLHPGAHVGAGAETGIQKIIEGLNEVIDPNQNVQIALETMAGKGSECGRTFEELAQIIDGVTHNEHLSVCFDTCHTHDAGYDVVSDFDGVLNEFDKIVGIDRLKVLHINDSKNVRGARKDRHENIGFGEIGFDALQYIVHHDQLKDIPKILETPYVGEDKKNKKPPYRFEIEMLKNKQFDEELLEKIKQQ
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: RS3_ECOBW
Sequence: MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLTKELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQINIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPEKPAAQPKKQQRKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: YACL_SHISS
Sequence: MDYEFLRDITGVVKVRMSMGHEVVGHWFNEEVKENLALLDEVEQAAHALKGSERSWQRAGHEYTLWMDGEEVMVRANQLEFAGDEMEEGMNYYDEESLSLCGVEDFLQVVAAYRNFVQQK
What are the official names of this protein?
UPF0231 protein YacL.
What is the protein family that this protein belongs to?
Belongs to the UPF0231 family.
Protein: MENG_MYCSS
Sequence: MSRATLDKNPHEVASMFDAVARRYDLTNTVLSLGQDRFWRRETCAALGIGPGDRVLDLAAGTAVSTVELAASGAWCVAADFSVGMLSAGRQRDVPKVAGDATRLPFADESFDAVTISFGLRNVVDHVAGLEEMARVTRPGGRLVVCEFSTPTNRAFATLYKEYLMKALPRMARAVASNPDAYVYLAESIRAWPDQAGLARRIEAAGWSQVRWRNLTGGIVALHAAVKPPR
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: THTPA_RAT
Sequence: MAQGLIEVERKFTPGPDTEERLQKLGATLEHRVTFRDTYYDTSELSLMLSDHWLRQREGSGWEFKCPGVTGVSGPHNEYVEVTSESAIVTQLFELLGSGEQETAGVAAVLGRLKLQEVASFITTRSSWKLALSGAHEEESLLTVDLDSTDFGYAVGEVEAVVHEKAEVPAALEKIISVSSMLGVPAQEKAPAKLLVYLQRFRPQDYQRLLEADSSGEATGDSVP
What is the function of this protein?
Hydrolase highly specific for thiamine triphosphate (ThTP).
What are the official names of this protein?
Thiamine-triphosphatase, ThTPase.
What is the protein family that this protein belongs to?
Belongs to the ThTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_THAPS
Sequence: MLKNPFIKDSGLNQYQPLINQINALETNLKTLTDTELRNKTFELKKRYQEEQDLNALTAEAFAITREASFRTLGLRHFDVQLIGGLVLNSGKISEMRTGEGKTLVATLPAYLNALTDKGVHIVTVNDYLASRDQISMGQIYRFLGLDTGLIQEDMAFLERQQNYKAEITYVTNNEVAFDYLRDNMASNLSQVVLPPFNYCIVDEVDSIFIDEAQVPLIISQAVETCIDKYIVAAEVAEYLEVNVHFKVDEKNRNIILTEQGTAQIEKILQVEDLYNPNDPWIPYILSAIKATALFFRNVHYIVQNNQIIIVDEFTGRIMPDRRWNEGLHQAVEAKEGVPIRQNTETAASITYQNFFLLYPKLSGMTGTAKTSEVEFEKIYNLPVEEIPTARPNLRKDLPDFVYKDSLTKWTAIARECKSIANTKQPILIGTTTVENSEMLADLLQEYQLSYRLLNAKPENVKRESEIVAQAGEIGSITIATNMAGRGTDIILGGNTTFKVRKQLYNILVSYKSKTNLTKLNTIFPLAIDIKFTSQKFLSVLNSLLNDPKFLSLSSTGILKFLNEIDQIRIPKITYQCSIKFLLNELSKFEKKNQTIDNKIVKNLGGLYIIGTERNNSRRIDNQLRGRCGRQGDPGTSRFFLSLEDSLFRNFGSSKLQNFMQNQLLDDLPLESNLLTKSLDAAQKRVEERDYDGRKYLFDYDDILNKQRNIVYYERRKLLESQSLRETILAYGEQVIKDIITLLKDPKFPKTNSMIEELFKTRLVSLNSDLNSLDSFELKTYLFQEFWLSYETKVLEFEICQTGLIRSFERTIILYYTDIAWKEHLQKIALLRDAVGWRSYGQRNPLFEFKEEAYNLFQNRNITIRHLLIRDFLHSFIL
What is the function of this protein?
Has a central role in coupling the hydrolysis of ATP to the transfer of proteins across the thylakoid membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma. Plastid, chloroplast thylakoid membrane; Peripheral membrane protein. Note=A minor fraction is associated with the chloroplast thylakoid membrane.
Protein: RS3A_STAMF
Sequence: MPARRKYAVRDKWKLKKWYEVIAPPVFGNIVIGTTPADDPLKLIGRVMETTLYDITGDITQVHVRLYFQIIDVKENKAITRFKGHELSRDYIKSLIRRKSSKIQGIFNVVTKDGYHLRLTIIALTSYRCKTSQKRAIRKIMEEYVKERVPQLTLDELIHEMVFGKMSAVIAERARKIYPIRKVEVYKSKLLMIPTPEGPKPAVVISPLQLGR
What are the official names of this protein?
30S ribosomal protein S3Ae, Ribosomal protein S1e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
Protein: CLPE_LACLM
Sequence: MLCQNCNINEATIHLYTSVNGQKKQIDLCQNCYQIMKSGGQEALFGAGNASNGNSDEPFNPFNDIFSALQGQDFNGAASNQTPPTQTGGRGPRGPQNPRAKQPKGMLEEFGINITESARRGEIDPVIGRDEEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEGLAQKIVDGDVPQKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRKRNDVIMFIDEIHEIVGAGSAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVDETITILRGIQARYEDYHHVKYTDEAIEAAAHLSNRYIQDRFLPDKAIDLLDESGSKKNLTLKFVDPEDINRRIADAESKKNEATKAEDFEKAAHFRDQISKLRELQKQEVTDEDMPVITEKDIEQIVEQKTQIPVGDLKEKEQTQLINLADDLKAHVIGQDEAVDKISKAIRRSRVGLGKPNRPIGSFLFVGPTGVGKTELAKQLAKELFGSSESMIRFDMSEYMEKHSVAKLIGAPPGYVGYEEAGQLTERVRRNPYSLILLDEIEKAHPDVMHMFLQILEDGRLTDAQGRTVSFKDSLIIMTSNAGTGKVEASVGFGAAREGRTKSVLGQLGDFFSPEFMNRFDGIIEFSALSKENLLKIVDLMLDEVNEQIGRNDIHLSVTQAAKEKLVDLGYNPAMGARPLRRIIQENIEDSIADFYIEHPEYKQLVADLIDDKIVISNQTQETAETTDEEVPAE
What is the function of this protein?
Along with ClpP could be necessary for degrading proteins generated by certain types of stress.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpE.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family. ClpE subfamily.
Protein: MSHA_STRCO
Sequence: MSQYVSRLGRRSPAASPRLRLNRKPRRVAMLSVHTSPLHQPGTGDAGGMNVYIVELAQRLAAINIEVEIFTRATTAALPPAVELAPGVLVRHVDAGPYEGLAKEELPAQLCAFTHGVMQAWAGHRPGHYDLVHSHYWLSGHVGWLAAQRWGAPLVHAMHTMAKVKNANLADGDTPEPAARVIGETQIVAASDRLIANTAEEADELVRHYAADPDKVAVVHPGVNLERFRPFPKGRVPGPGQHGNARAAARARLGLPQDALIPLFAGRIQPLKAPDILLRAVAVLLDERPELRSRIVVPVVGGPSGSGLAKPEGLQKLAARLGIADVVRFRPPVGQEQLADWFRAASVLVMPSYSESFGLVAIEAQAAGTPVLAAAVGGLPVAVRDGHTGRLVHGHDPAAYARVLRDFADNPDLTPRMGDAAARHAQSFGWDSAAATTADVYTAAIQSYRRRVRSHHG
What is the function of this protein?
Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
What are the official names of this protein?
D-inositol 3-phosphate glycosyltransferase, N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase, GlcNAc-Ins-P N-acetylglucosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. MshA subfamily.
Protein: PR1_MEDSA
Sequence: MGVFNFEDETTSIVAPARLYKALVTDSDNLIPKVIDAIQSIEIVEGNGGAGTIKKLTFVEGGETKYDLHKVDLVDDVNFAYNYSIVGGGGLPDTVEKISFESKLSAGPDGGSTAKLTVKYFTKGDAAPSEEEIKGGKARGDGLFKALEGYVLANPDY
What are the official names of this protein?
Class-10 pathogenesis-related protein 1, MSPR10-1.
What is the protein family that this protein belongs to?
Belongs to the BetVI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPG_PSEPG
Sequence: MPELPEVETTRRGIAPHLEGQRVSRVVVRDRRLRWPIPEDLDVRLSGQRIVSVERRAKYLLINAEVGTLISHLGMSGNLRLVELGLPAAKHEHVDIELESGLMLRYTDPRRFGAMLWSLDPLNHELLLRLGPEPLTDLFDGERLFQLSRGRSMAVKPFIMDNAVVVGVGNIYATEALFAAGIDPRREAGGISRARYLKLAIEIKRVLAAAIEQGGTTLRDFIGGDGQPGYFQQELFVYGRGGQPCKVCGTALREVKLGQRASVYCPRCQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: Y322_HAEDU
Sequence: MITRIDVTNRFSEVAIYNGIAYFAGQVPTDESKDAYQQTQQVLSEIDKYLAKSNTDKSRILMATVYLANMADYTEMNRAWDEWVAPNNAPPRAAIEARLANPNWKVEIVITAAINHQ
What are the official names of this protein?
RutC family protein HD_0322.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: MET3_ASPTE
Sequence: MANSPHGGVLKDLLAGDAPRHDELAAEAETLPAIVLSERQLCDLELIMNGGFSPLEGFMTQKDFDGVCENCRLADGHLFSMPITLDASQQVISDSNLKPGSRVTLRDFRDDRNLAILTIEEKEAKLVFGGDPEHPAIKYFNTKVEDFYIGGKIEAVNKLNHYDYVALRYSPAELRVHFDKLGWTRVVAFQTRNPMHRAHRELTVRAARARQANVLIHPVVGLTKPGDIDHFTRVRAYQALLPRYPNGMAVLGLLPLAMRMGGPREAIWHAIIRKNHGATHFIVGRDHAGPGKNSKGEEFYGPYDAQHAVEKYREELGIEVVEFQQVTYLPDTDEYKPKDEVPAGIKTLDISGTELRNRLRTGAHIPEWFSYPEVVKILLRESSPPRATQGFTIFLTGYMNSGKDAIARALQVTLNQQGGRSVTLLLGDTVRHELSSELGFSAEDRHTNVQRIAFVAGELTRAGAAVIAAPIAPYERSRKAAREAVSGLGGSFFLVHVNTPLEYCEKTDKRGIYAKARRGEIKGFTGVDDPYEAPENADLVVDVSKQSVRSIVHEIILMLESEGYFDRL
What is the function of this protein?
Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP.  Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the APS kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_METNO
Sequence: MSQSDADALPNVHVRAEVLVQALPHMQRYDEEIVVIKYGGHAMGDRAAAEDFAEDIVLLEQSGLKPVIVHGGGPQIGRMLDRLGIKSEFREGLRVTDEATVEVVEMVLAGSINKQIVGWISAEGGKAIGLCGKDGNMVQARRATRTVVDPDSNIERHVDLGLVGEPERVNRAVLDAVLKAELIPVLAPVAVGSDGQTYNVNADTFAGAIAGALRAKRLLLLTDVPGVLDKDKKLIPELSIEDCRRLIADGTITGGMIPKIETCIYAIEQGVEAVVILDGKVPHAVLLELFTDYGAGTLIRRSGA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_METFK
Sequence: MTVINMTDLDLAGKRVFIRADLNVPVSDGKVTSDARITASIPTIRHALDAKARVMVTSHLGRPEEGVYSEENSLQPVADVLADKLGQPVRLIKDWVDGGFEVAEGEVVLLENCRFNKGEKKNAEETARKYAALCDVFVMDAFGTAHRAEASTYGVAQYAPVAAAGLLLVGELDALGKALCEPARPMVAIVGGSKVSTKLTVLESLAEKVDQLVVGGGIANTFLKAAGKPIGRSLSEDDLVPTAQCLMEKMAKRGAAVPIAVDVVCGKQFDANEPAVLKSAEDVADDDMIFDIGPESAKQLAEIILNAGTVVWNGPVGVFEFDQFGEGTKTIADAIAKTKAFTLAGGGDTIAAIQKYDIYDKVSYISTAGGAFLEFLEGKKLPAVEILEQRAKG
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 1A01_PANTR
Sequence: MAVMPPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDEETRSAKAHSQTDRVDLGTLRGYYNQSEDGSHTIQIMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHAAEQRRAYLEGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASSDSAQGSDVSLTACKV
What is the function of this protein?
Involved in the presentation of foreign antigens to the immune system.
What are the official names of this protein?
Patr class I histocompatibility antigen, A-2 alpha chain, ChLa class I histocompatibility antigen, A-2 alpha chain.
What is the protein family that this protein belongs to?
Belongs to the MHC class I family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: TCYP_BACLD
Sequence: MTLFVVINIIVMLGLMALLYMMQKKHVSFSKRVFTALGIGIVFGFALHFIYGSSSETITQTSDWFNIAGGGYVKLLQMIVMPLVFISILGAFTKLKLTHNIGKISGLIIGLLIATTAVAAAVGIASALAFDLQAVHVDQGQAETMRGAELEQKSQDMEAKTLPQQIVELLPGNPFLDFTGARPTSTIAVVIFAAFLGIAYLGVNRKQPEQAELFKKMVDAVYAIIMRVVTLILRLTPYGVLAIMTKTIATSDLDSIAKLGKFVIASYAALIVMFIIHLLLITFSGLNPVTYLKKAFPVLVFAFTSRSSAGALPLNIKTQRSLGVPEGIANFAGSFGLSIGQNGCAGIYPAMLAIMIAPTVGQNPLDPSFLFTVIAVVAISSFGVAGVGGGATFAALLVLSALNMPVALAGLLISVEPLIDMGRTALNVSGSMTSGLVTSKVTNELEKDTYQDRTNIIEAEV
What is the function of this protein?
Mediates uptake of L-cystine, the oxidized form of L-cysteine.
What are the official names of this protein?
L-cystine uptake protein TcyP, Transporter of cystine TcyP.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MTA1_ACEPA
Sequence: MNKDEVVVSLFAGAGGFSSGFSQAGLKPLFGAEINADACQTYQENVGSPCHQLDLSTVDPSHIEMLTGGKRPFVVIGGPPCQGFSTAGPRNFADPRNLLIFNYLNIVERLSPRWLIFENVEGLLTSGGGRDLARLVREFVDMGYSVRLQKVNLAAYGVPQTRKRVLIIGNRLGIDFQFPEELYSFDSGKAKKASGKPLAPSLAEAVAGLGPAASDKDALVPYASSEPVNAFDARMRAGNRVEVVTHHVRVEAAERMQVELLKPGQTMKDLPPELWHESYRRRANRRVSDGTPTEKRGGAPSGIKRLHGNLQSLTITGPAAREFIHPTEHRPLTIRECARIQTFPDKYRWVGNNASVIQQIGNAVPPLAAERLAKHLRDIDGSFGADTRPAGAMSAKLLGFVLTEALGMSPALKSTEALLAEMHQGGFVF
What is the function of this protein?
A beta methylase that recognizes the double-stranded sequence 5'-GTGCAC-3', probably methylates C-4 on both strands, and protects the DNA from cleavage by the ApaLI endonuclease.
What are the official names of this protein?
Type II methyltransferase M.ApaLI, M.ApaLI, Cytosine-specific methyltransferase ApaLI, Modification methylase ApaLI.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Protein: DAPA_LEGPC
Sequence: MFSGSIVALVTPMRNDSVDVHHLRELVEFHIAKGTHALVAAGTTGEAGTLSHSEKLLVIKTVIEQAKERVPVIAGTAMNATKDCIELTQQAMEYGAHAAFIMTPAYIKPTQEGLYLHYSHIAQSVAIPIILYNVPGRTACDMLPETVARLAKISNIIGIKEATGQMTRLQQILRLCEGSIDVYSGDDLTAAQWLLSGAKGVISVTANVAAKLMAKMCDLAMDDDQAGCLRIQEQLMPLHELLFVESNPIPVKWAMKKMGLIGGELRLPMTELSEKHHQALEKVLKNLELI
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRC_STRPQ
Sequence: MILIKNGRVMDPKSQRDQVADVLIDGKQIVKIASAIECQEAQVIDASGLIVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDVETLQEVLASAAKEKIHIYTNASVTQAFNGKDVTDFKALLEAGAVSFSDDGIPLESSKVLKEAFDLANANQTFISLHEEDPQLNGVLGFNEGIAEEHFHFCGATGVAEYSMIARDVMIAYDRQAHVHIQHLSKAESVQVVAFAQQLGAKVTAEVSPQHFSTTEDLLLTAGTSAKMNPPLRTQRDRLAVIEGLKSGVITVIATDHAPHHKDEKAVDDMTKAPSGMTGLETSLSLGLTHLVEPGHLTLMSLLEKMTLNPALLYGFDAGYLAENGPADLVIFADKQERLITENFASKASNSPFIGNKLKGVVKYTIADGEVVYPN
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: GLYCO_COCAV
Sequence: MNFLLLTFIVLPLCSHAKFSIVFPQSQKGNWKNVPSSYHYCPSSSDQNWHNDLLGITMKVKMPKTHKAIQADGWMCHAAKWITTCDFRWYGPKYITHSIHSIQPTSEQCKESIKQTKQGTWMSPGFPPQNCGYATVTDSVAVVVQATPHHVLVDEYTGEWIDSQFPNGKCETEECETVHNSTVWYSDYKVTGLCDATLVDTEITFFSEDGKKESIGKPNTGYRSNYFAYEKGDKVCKMNYCKHAGVRLPSGVWFEFVDQDVYAAAKLPECPVGATISAPTQTSVDVSLILDVERILDYSLCQETWSKIRSKQPVSPVDLSYLAPKNPGTGPAFTIINGTLKYFETRYIRIDIDNPIISKMVGKISGSQTERELWTEWFPYEGVEIGPNGILKTPTGYKFPLFMIGHGMLDSDLHKTSQAEVFEHPHLAEAPKQLPEEETLFFGDTGISKNPVELIEGWFSSWKSTVVTFFFAIGVFILLYVVARIVIAVRYRYQGSNNKRIYNDIEMSRFRK
What is the function of this protein?
Attaches the virus to host cellular receptor, inducing endocytosis of the virion.  In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane (By similarity).
What are the official names of this protein?
Glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the vesiculovirus glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein.
Protein: GRPE_MYCTU
Sequence: MTDGNQKPDGNSGEQVTVTDKRRIDPETGEVRHVPPGDMPGGTAAADAAHTEDKVAELTADLQRVQADFANYRKRALRDQQAAADRAKASVVSQLLGVLDDLERARKHGDLESGPLKSVADKLDSALTGLGLVAFGAEGEDFDPVLHEAVQHEGDGGQGSKPVIGTVMRQGYQLGEQVLRHALVGVVDTVVVDAAELESVDDGTAVADTAENDQADQGNSADTSGEQAESEPSGS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU1_ECO45
Sequence: MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQTIARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIERAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAINAGATTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAVHAGARQVEGAMNGIGERAGNCSLEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQICNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMDEMGYKESEYNLDNLYDAFLKLADKKGQVFDYDLEALAFIGKQQEEPEHFRLDYFSVQSGSNDIATAAVKLACGEEVKAEAANGNGPVDAVYQAINRITDYNVELVKYSLTAKGHGKDALGQVDIVANYNGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQHNENNKETV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: SYFB_SCHPO
Sequence: MPTISCDKEELYKALGREYTTQEFDELCFQFGIELDEDTTNDPERSPSERPSLKIDIPANRYDMLCLEGIAQALNVFNRRMATPQYKLLPSTTSLTISPETSEIRPYAAAAILRGVKLDPIRYQSFIALQDKLHANLCRNRTLVAIGTHDFSVMEGPFTYEALKPEEINFVPLNQTQEINGSNLLEFYKDSKHLSRYLHIIANSPRYPVILDAKRRVCSLPPIINSEFSKISVDTRDIFIDVTATDKTKLEIVVNMMTTMFSCYCEEPFTIEPVNIISEHNGCTRVTPNLNPTCFKADIDYLNEACGLSLPEDEICHLLTRMMLTAKPNPNDSKTLLVYVPPLRADILHQCDIMEDLGIAYGYDNLKHTYPAHSVTFGKPFEVNRLADIIRNEVAYAGWSEVMPFILCSHDENYAWLRKTDDSKAVQLANPKTLEFQVVRSSLLPGILKTVRENKNHALPIKIFEVSDVAFCDYSRERMTRNERHLCAIFAGLNSGFEQIHGLLDRVMLMLNTKRIMNPKDSDAVGYWIEAEDDSTFFPGRCAAVYYRKDFGTAGIRVGVFGVLHPLVLEKFELTSAASAVEIDLTLWV
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LPXB_WIGBR
Sequence: MKNILIGIVAGEASGDFLGAELIKSLNIIHSNIKFVGIAGPLMLKEKNVESWFSIEELSIMGIFEIINRIPKILNIRNKIFNRLSFLKPDLFIGIDSPEFNIHLEFKLKKNGIKIIHYVSPSIWAWRKSRIFKIKESVDKVLALLPFEKKIYDDFNIPCKFVGHPLADKIPLYPDKYSIRSNLEIDKNSVCLALLPGSRLTEINLLSKKFLYAAKIIKKNIFNLKILVPMVNSLLKKRFEEIKREVAPDLPITIFDNFSYEVMACSDFSIVTSGTATLECMLSKCPMVVGYCMKKINFFLLKKIIKINYISLPNLIAGKKIVPEKIQNECNPEVLAKEILIIFNDKKKYKKTKKIFYKLHKKIRCNSSYNAACSASCLINKLTIK
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.