PharMolix/UniProtQA huggingface dataset:
Protein: MIC27_MOUSE
Sequence: MAAFRMGKLTTIPAGLIYASINVRLAKEEEPKKQLVRPDQLPIYTAPPLHSKYVEEQPGNLQRGFASIRTTTVYYIGWCKSIYLFMKNGVMDTVQFGKDAYVYLKNPPQDFLPKMGVITASGLAGLLSARKGSRFKKIAYPLGLATLGATVCYPAQSVIIAKITGKKAYATSQQIFQAIKSLWTQKSENESLPEPKEESKEGRSDEIHASLPDLKHSVSLPKELASATVIKSESTSGTTQFIPDPKLMDHGQSHPDDKDMYSTRS
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.  Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol.  Plays a crucial role in crista junction formation and mitochondrial function.
What are the official names of this protein?
MICOS complex subunit Mic27, Apolipoprotein O-like, Protein FAM121A.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein. Mitochondrion.
Protein: DTML_BURPS
Sequence: MGNGERPPARRPDSSGSPPPAADAPAASNHPFSSHDTKHMTSRRLASRTAVAASLSALMLAACGGDDSANAPTAGGAAPLTPAVASPAGPTGSTPGSTPGATTAPAPSSTSAGQLSVDKMAFAQTHVVPSGGLSWTLPNASASLRPISRRDALVLVAIGQADAVQPVLEAWKDGAKLGALALSPPSALPPTESGGRAYANDRWSAVVPAAWMVPGVSFSVSASNYTSSVAQAPVFGTDADVQLTILPFYLFGADDTNSPPLSTTQAPDAATQQEIFAKWPTAELKVRTHPAGRFSLATVVVGPRADRTGAAQPAYPVTALDQQKDGYGVMSAMLTLITNMRTANGDGPLNNQYYAPLIALNSNGQFANLGGGLGGVGSGAAVGDHRYTGIFIHEQGHAFGLNHAGDEYAKGAYPYAGGSLSGSVWGYDPNHREFLDVLVPTTASSYAKCASSHQLDAQGRCYKQDPMQGGAGDQSSGYKFATFSDYNTGRMQAWIASRVLADPASSTGYSKWDSAAQARAPYTPTTDNNGLYGVNQNLPVQAGVPVHTIVVSFSKAGSAGASYIYPPFSYTGNLIATFDPTSAADRQAITVDKGTYPWYCKGTGCDYTLRVTYADGSRTYRVLQGGFRAWWTPTVDDANATNPLSGSSFRVWAINVPGDKRIGKIELLDTPMVWNGMPANPTVLLSR
What are the official names of this protein?
Dictomallein.
What is the protein family that this protein belongs to?
Belongs to the dictomallein family.
Protein: SCAR5_DANRE
Sequence: MENRAMYLTTTHEDRENSSFYEESYDGMNLSKLNLCEEVNSTKYRRKTDNRCGQLDSLTSIKYAIVSLYILVLLTIFGLCIAVSKSHASWRREEALLENVTRLGEQSETLQMSLSQIPSQSDLLENIWKLESLFHNHTEQLRLLGLLTQGLERDIKDLQAFAEHTTDSVAQLWDHLSMISHSSQRNSTHLGDELASTAGSIREQDALLKTMVGNVETLQERLEDMGWTLQTLNHSLGGDVSLHQIKIYELQEKIVNVTHDTLGMKITQTHLEDQLRNEIQVLNVVTADLRLKEWEHSMALKNLTIFQGPPGPKGEKGDVGPLGPDGIPGWIGPRGLTGEKGVQGPRGLAGRNGQDGHNGDKGEVGPEGPKGVRGERGPKGEKGERGDKQGEKVEDAVVRLVNGSGPHEGRVEVLHDLRWGTVCDDVWDIKDGDVVCRMLGFRGAKEIHKTGRFGQGTGLIWMDDVACVGTEDSIDLCKFSGWGKTNCGHVEDAGVTCNV
What is the function of this protein?
Ferritin receptor that mediates non-transferrin-dependent delivery of iron.  Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell.  Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways.
What are the official names of this protein?
Scavenger receptor class A member 5.
What is the protein family that this protein belongs to?
Belongs to the SCARA5 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: MYO1C_RAT
Sequence: MRYRASALGSDGVRVTMESALTARDRVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYTRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNHGERNFHVFYQLLEGGEEEALRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKVVRKALSVIDFTEDEVEDLLSIVASVLHLGNIHFAADEDSNAQVTTENQLKYLTRLLGVEGTTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVRKINRSLASKDAESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTIKHHPHFLTHKLADQKTRKSLDRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSTNPIMAQCFDKSELSDKKRPETVATQFKMSLLQLVEILRSKEPAYIRCIKPNDAKQPGRFDEVLIRHQVKYLGLMENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPVWTGRPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDSLEVRRQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFILRHAPRCPENAFFLDHVRTSFLLNLRRQLPRNVLDTSWPTPPPALREASELLRELCMKNMVWKYCRSISPEWKQQLQQKAVASEIFKGKKDNYPQSVPRLFISTRLGTEEISPRVLQALGSEPIQYAVPVVKYDRKGYKPRSRQLLLTPSAVVIVEDAKVKQRIDYANLTGISVSSLSDSLFVLHVQREDSKQKGDVVLQSDHVIETLTKTALSADRVNNININQGSITFAGGPGRDGIIDFTSGSELLITKAKNGHLAVVAPRLNSR
What is the function of this protein?
Myosins are actin-based motor molecules with ATPase activity.  Unconventional myosins serve in intracellular movements.  Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments.  Involved in glucose transporter recycling in response to insulin by regulating movement of intracellular GLUT4-containing vesicles to the plasma membrane.  Component of the hair cell's (the sensory cells of the inner ear) adaptation-motor complex.  Acts as a mediator of adaptation of mechanoelectrical transduction in stereocilia of vestibular hair cells.  Binds phosphoinositides and links the actin cytoskeleton to cellular membranes (By similarity).
What are the official names of this protein?
Unconventional myosin-Ic, Myosin I beta, MMI-beta, MMIb, Myosin heavy chain myr 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, ruffle. Cell projection, stereocilium membrane. Cytoplasmic vesicle. Note=Colocalizes with CABP1 and CIB1 at cell margin, membrane ruffles and punctate regions on the cell membrane. Colocalizes in adipocytes with GLUT4 at actin-based membranes. Colocalizes with GLUT4 at insulin-induced ruffles at the cell membrane. Localizes transiently at cell membrane to region known to be enriched in PIP2. Activation of phospholipase C results in its redistribution to the cytoplasm (By similarity).
Protein: NADK_PSYA2
Sequence: MPHLHESELFHAIKNPAFRRIGLMGRARTRSVTQSIGQIAQIINDMNLTLIMDVQTANLPTLNLTEIERVKIVKRSLIGEICDLVIVVGGDGSILHAAEALARYRVPVLGVNRGRLGFLADVKPDEAAFKLRQVLMGNYQLDHRFLLTMEIREGRKIIHEDMALNDVVLHAGKSVHMIDFQMKIDGHDVYRQHSDGLIVATPTGSTAYALSGGGPIIHPSMDAICLVPMHPHTLSSRPIVVSGTSEICIRIHEDNRTQPMVSADGKPSTPLDQEQRLYIRKHPDKLTLLHPPGFDFYEACRTKLHWNVHAEEFSLDVDDDIMDDE
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_RHOOB
Sequence: MATYAIVKTGGKQYKVAVGDLVKVEKIEGEPGTAVSLAPVLVVDGSDLTTDADKLAKISVTGEVVEHTKGPKIRIHKFKNKTGYHKRQGHRQKLTVLKVTGIK
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RECR_BPP1
Sequence: MSNLLTVHQNLPALPVDATSDEVRKNLMDMFRDRQAFSEHTWKMLLSVCRSWAAWCKLNNRKWFPAEPEDVRDYLLYLQARGLAVKTIQQHLGQLNMLHRRSGLPRPSDSNAVSLVMRRIRKENVDAGERAKQALAFERTDFDQVRSLMENSDRCQDIRNLAFLGIAYNTLLRIAEIARIRVKDISRTDGGRMLIHIGRTKTLVSTAGVEKALSLGVTKLVERWISVSGVADDPNNYLFCRVRKNGVAAPSATSQLSTRALEGIFEATHRLIYGAKDDSGQRYLAWSGHSARVGAARDMARAGVSIPEIMQAGGWTNVNIVMNYIRNLDSETGAMVRLLEDGD
What is the function of this protein?
Catalyzes site-specific recombination between two 34-base-pair LOXP sites.  Its role is to maintain the phage genome as a monomeric unit-copy plasmid in the lysogenic state.
What are the official names of this protein?
Recombinase cre.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: DAPF_SHEFN
Sequence: MIHFTKMHGLGNDFMVVDGVTQNVFFSPEQIRRLADRNFGIGFDQLLLVEPPYDPDLDFHYRIFNADGSEVEQCGNGARCFARFVRNKGLTQKNKIRVSTNSGKITLRIERDGNVTVNMGVPVIEPSQIPFKAKKSEKTYLLQTPMQTYLCGAISMGNPHCVIQVEDVQTVNVDEIGSSLTRHERFPKGVNVGFMQVINPGHIKLRVYERGAAETLACGTGACAAAAVGQLQDKLDKQVRVDLPGGSLIINWEGEGKPLWMTGPAEHVYDGQIQL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IBPA_ESCF3
Sequence: MRNFDLSPLYRSAIGFDRLFNHLENNQSQSNGGYPPYNVELVDENHYRIAIAVAGFAESELEITAQDNLLVVKGAHADEQKERTYLYQGIAERNFERKFQLAENIHVRGANLVNGLLYIDLERVIPEAKKPRRIEIN
What is the function of this protein?
Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpA, 16 kDa heat shock protein A.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y545_METJA
Sequence: MVGKMKKVIIPLLISLFIFLIPNYALNPEIIVTPEKCLVNNSVYVIFQWRAPYNVEDFNVTVLSDAVVFKNSTLYYAGVAEDAKVFHIFEGEAVTPGNHTINVQMSYIIDGTLIKKKFLLNISILTLPENIYVSYNNTYNRDEENTSLLENITKIFENTTNVTTPNSTNAIINETNITQNKTNISKNIDIGNITKANTTSQEKITQKFNNTSTQTIENVQKDKGNNWLMYGILGLIIGIVFGFVVMYIIKI
What are the official names of this protein?
Uncharacterized protein MJ0545.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS21_SHEPC
Sequence: MPIIKVRENEPFDVALRRFKRSCEKAGILADVRAREFYEKPTTARKRAKAAAVKRLAKKLSRENARRVRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: CASA1_MOOTA
Sequence: MYILITYDVSTETEAGKKRLRKVAQVCKDFGQRVQKSVFECSVNEAQFEQLKHRLLQCIDEKSDSLRIYRLREPAKKYIQEYGVNLTIDFDAPLVL
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Functions as a ssRNA-specific endoribonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas2 1.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: NUOH_BURCH
Sequence: MSLFDTINAGGAELLGFAWPTVWAVVRILVVSVVILLCVAYLILWERKLIGWMHVRLGPNRVGPGGLLQPIADVLKLLLKEVIQPSAASRWLYLIAPVMTVVPAFAVWAVIPFQAEAVLANVNAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAAAQMVSYEISMGFALVLVLMTAGSLNLSEIVGSQQHGFFAGHGVNFLSWNWLPLLPAFVVYFISGIAETNRHPFDVVEGESEIVAGHMIDYSGMAFALFFLAEYINMIVISALAATLFLGGWDAPFEFLSFIPGIFWLVLKVFALLSVFIWVRATFPRYRYDQIMRLGWKVFLPVTVVWVIVVGFWMMSPLNIWVK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YCF15_OENPI
Sequence: METPVSSLFWTLAPRNNMLLLKDGRIEILDQNTMYGWYELPKQEFLNSVRTIQIFTTKKYCIPFRIGPERRRKAGMPTGV
What are the official names of this protein?
Putative uncharacterized protein ycf15, ORF 80.
What is the protein family that this protein belongs to?
Belongs to the ycf15 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ERG_ARATH
Sequence: MKAFRSLRILISISRTTTKTTPRNPHQAQNFLRRFYSAQPNLDEPTSINEDGSSSDSVFDSSQYPIDDSNVDSVKKPKEATWDKGYRERVNKAFFGNLTEKGKVKVAEEESSEDDEDSVDRSRILAKALLEAALESPDEELGEGEVREEDQKSLNVGIIGPPNAGKSSLTNFMVGTKVAAASRKTNTTTHEVLGVLTKGDTQVCFFDTPGLMLKKSGYGYKDIKARVQNAWTSVDLFDVLIVMFDVHRHLMSPDSRVVRLIKYMGEEENPKQKRVLCMNKVDLVEKKKDLLKVAEEFQDLPAYERYFMISGLKGSGVKDLSQYLMDQAVKKPWEEDAFTMSEEVLKNISLEVVRERLLDHVHQEIPYGLEHRLVDWKELRDGSLRIEQHLITPKLSQRKILVGKGGCKIGRIGIEANEELRRIMNRKVHLILQVKLK
What is the function of this protein?
Has a crucial role in plant growth and development, possibly by influencing mitochondrial division.
What are the official names of this protein?
GTP-binding protein ERG.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
Protein: CHEB2_XANC5
Sequence: MVVDDSAVVRQVLVGVLNDAPGIDVIATAADPLLAIEKMRQHWPDVIVLDVEMPRMDGITFLRKIMSERPTPVVICSTLTEKGARVTMDALAAGAVAVVTKPRLGLKQFLTDSADELVATVRSAARANVKRLAARVTAAPLEAEVKHTADIILPAQSGRALAQTTERIVAIGTSTGGTQALEEVLTALPRVCPGIVIVQHMPEKFTAAFAARLNGLCQIAVKEAANNDRVMPGRALIAPGGKHLLLRRSGAQYFVEVLEGPPVNRHRPSVDVLFRSAARAAGSNALGIIMTGMGDDGAAGLLEMRQAGARTVAQDEHTSIVFGMPKEAIKRGGADRILPLGAMAREIVTQLQ
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PMTI_ARATH
Sequence: MAKENSSHSLAEAKRKRLTWILCVSGLCILSYVLGSWQTNTVPTSSSEAYSRMGCDETSTTTRAQTTQTQTNPSSDDTSSSLSSSEPVELDFESHHKLELKITNQTVKYFEPCDMSLSEYTPCEDRERGRRFDRNMMKYRERHCPSKDELLYCLIPPPPNYKIPFKWPQSRDYAWYDNIPHKELSIEKAIQNWIQVEGERFRFPGGGTMFPRGADAYIDDIARLIPLTDGAIRTAIDTGCGVASFGAYLLKRDIVAMSFAPRDTHEAQVQFALERGVPAIIGIMGSRRLPYPARAFDLAHCSRCLIPWFQNDGLYLTEVDRVLRPGGYWILSGPPINWKKYWKGWERSQEDLKQEQDSIEDAARSLCWKKVTEKGDLSIWQKPINHVECNKLKRVHKTPPLCSKSDLPDFAWYKDLESCVTPLPEANSSDEFAGGALEDWPNRAFAVPPRIIGGTIPDINAEKFREDNEVWKERISYYKQIMPELSRGRFRNIMDMNAYLGGFAAAMMKYPSWVMNVVPVDAEKQTLGVIFERGFIGTYQDWCEGFSTYPRTYDLIHAGGLFSIYENRCDVTLILLEMDRILRPEGTVVFRDTVEMLTKIQSITNGMRWKSRILDHERGPFNPEKILLAVKSYWTGPSS
What are the official names of this protein?
Probable methyltransferase PMT18.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: NTF3_CYLRU
Sequence: IQSTSMDQGBLSEDSMNSFIRTLIQAGIWKNKVPKQTARTKDGTQTAVKKTKAEPDVVANKDRLGFQPIVSVDAELLRQQRRFSSPRVLLSENTPLEPPPLYLTEEPMGLNRTSRRKRFAEGKSHRGEYSVCDSESRWVTDKSSAVDIRGHQVTVLGEIRMGPS
What is the function of this protein?
Seems to promote the survival of visceral and proprioceptive sensory neurons.
What are the official names of this protein?
Neurotrophin-3, NT-3.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: NBLIK_MYCLE
Sequence: MTSDEVRDGAGSPADSSKGNKCTAAGMFQAAKRSTVSAARNIPAFDDLPVPSDTANLREGANLNSTLLALLPLVGVWRGEGEGRGPNGDYHFGQQIVVSHDGGNYLNWEARSWRLNDAGEYQETSLRETGFWRFVSDPYDPTESQAIELLLAHSAGYVELFYGRPRNASSWELVTDALACSKSGVLVGGAKRLYGIVEGGDLAYVEERVDADGGLVPNLSARLYRFAG
What are the official names of this protein?
Ferric nitrobindin-like protein.
What is the protein family that this protein belongs to?
Belongs to the nitrobindin family.
Protein: MTAD_BACC7
Sequence: MKTTYVNATIVTMNEQNEVIENGYIIVENDQIIDVKSGEFANDFEVDEVIDMKGKWVLPGLVNTHTHVVMSLLRGIGDDMLLQPWLETRIWPLESQFTPELAVASTELGLLEMVKSGTTSFSDMFNPIGVDQDAIMETVSRSGMRAAVSRTLFSFGTKEDEKKAIEEAEKYVKRYYNESGMLTTMVAPHSPYTCSTELLEECARIAVENQTMVHIHLSETEREVRDIEAKYGKRPVEYAASCGLFKRPTVIAHGVVLNDNERAFLAEHDVRVAHNPNSNLKLGSGIANVKAMLEAGIKVGIATDSVASNNNLDMFEEMRIATLLQKGIHQDATALPVETALTLATKGAAEVIGMKQTGSLEIGKCADFITIDPSNKPHLQPADEVLSHLVYAASGKDISDVIINGKRVVWNGECKTLDEERIIFEASRYKRGLQR
What is the function of this protein?
Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively.  Is also able to deaminate adenosine.
What are the official names of this protein?
5-methylthioadenosine/S-adenosylhomocysteine deaminase, MTA/SAH deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
Protein: GLPG_SHIBS
Sequence: MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESQAERVRAELARFLENPADPRYLAASWQAGHTGSGLHYRRYPFFAALRERAGPVTWVVMIACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALIWIIAGWFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK
What is the function of this protein?
Rhomboid-type serine protease that catalyzes intramembrane proteolysis.
What are the official names of this protein?
Rhomboid protease GlpG, Intramembrane serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TBB7_MAIZE
Sequence: MREILHIQGGQCGNQIGAKFWEVICDEHGIDHTGKYAGDSDLQLERINVYYNEASGGRFVPRAVLMDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVLDVVRKEAENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLATPTFGDLNHLISATMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQQYRALTVPELTQQMWDSKNMMCAADPRHGRYLTASAMFRGKMSTKEVDEQMLNVQNKNSSYFVEWIPNNVKSSVCDIPPIGLKMSSTFVGNSTSIQEMFRRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVAEYQQYQDATAEDEEYEEEEEEEEET
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-7 chain, Beta-7-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: HSLU_ALTMD
Sequence: MSEMTPREIVHELDRHIIGQQDAKRAVSIALRNRWRRMQLEPELRQEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVETIIRDLADIAVKMTKENEMKKVKFRAEEAAEERILDVLLPPPEDAWGNKEDVEDRGTRQAFRKKLRQGDLDDKEIEIDVALPQVGVEIMAPPGMEEMTNQLQGMFQNLSGSQKKKKKLKIKEALKLLIEEEAARLVNQEDLKEKAIESVEQHGIVFVDEIDKICKREGNNSGDVSREGVQRDLLPLVEGSTVSTKHGMVKTDHILFIASGAFQMSKPSDLIPELQGRLPIRVELSALKVGDFKRILTEPNASLTQQYIALMKTEGVDIRFDDSGIQRIAEAAWQVNERTENIGARRLHTVLERLMEDISFDASEKSGESFVIDADYVNNHLETLVDNEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDX1_XENLA
Sequence: MAAFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQIVYETLKDQQEGKKGKASVKTGSTVLNKWQMNPYDRGSAFAIGSDGLCCQSREIKEWHGCRSTRGVNKGKYYYEVSCHDQGLCRVGWSTLSASLDLGTDKFGFGFGGTGKKSHNKQFDNYGEEFTMHDTIGCYLDIDNSIVKFSKNGKDLGLAFQIPSHMKNQAFFTSCVLKNAELKFNFGEEDFKFPPKDGFVALSKAPDGHVVKSQNTGSAQVSQTKSLPNAPKALIIEPSRELAEQTLNNVKQFKKYVDNPKLRELLIIGGVAAKEQLTILENGVDIVVGTPGRIDDLISTGKLSLSQVRFLVLDEADGLLSQGYSDFINRIYGQIPQITSDGKRLQVIVCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPETVHHVVVPVNPKKDKQWEKLAKNHIRTDGVHDKDNTRPGGNSAEVWSEAIKVLKGEYIVRAIKEHKMDQAIIFCRTKLDCDNMEQYFIQQGGGPDKKGHQFSCVCLHSDRKPPERKHNLERFKKCEVRFLICTDVAARGIDIRGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVASEKEKVWYHVCSSRGKGCYNTRLKEDGGCTIWYNEMQLLSEIEEHLTCTISQVEPDIKVPLDDFDGKVVYGQRRATGGGLYKGHVDILAPTVQELASLEKEAQTSFLHLGYLSNQLFRSF
What is the function of this protein?
Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes.  Possesses 5' single-stranded RNA overhang nuclease activity.  Acts as a positive regulator of transcription.  May be involved in 3'-end cleavage and polyadenylation of pre-mRNAs.  Binds DNA and RNA.  Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit rtcb (By similarity).  Binds (via helicase ATP-binding domain) on both short and long poly(I:C) dsRNA (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DDX1, DEAD box protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasmic granule. Cytoplasm, cytosol. Mitochondrion.
Protein: ABHDA_BOVIN
Sequence: MAGVGLAAVPAWVPCRRWGLAAVTFGFHHGLSTLLARKTERAPQWLRACRHKTSISFLSRPDLPNLAYKRLKGKSPGIIFIPGYISNMNGTKALAIEEFCKSLGHAYIRFDYSGVGNSDGNLEECTVGKWRKDVLSIIDDLAEGPQILVGSSLGGWLMFHAAIARPQKVVALVGVATAVDGLVTQFNQLPIETKKEIEMKGVWPMPSKYSEEGVYRIQYSVIKEAEHHCLLHSPIPVKCPVRLLHGMKDDIVPWHTSVQVADRVVSTDVDVILRKNSDHRMKEKADIQLLVYTIDDLIDKLSTIVH
What is the function of this protein?
Acts as an acyl-protein thioesterase that hydrolyzes fatty acids from acylated residues in proteins.  Regulates the mitochondrial S-depalmitoylation of the nucleophilic active site residue of peroxiredoxin-5/PRDX5, a key antioxidant protein, therefore modulating mitochondrial antioxidant ability.  Also catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, an active metabolite of the immunosuppressant drug mycophenolate.
What are the official names of this protein?
Palmitoyl-protein thioesterase ABHD10, mitochondrial, Acyl-protein thioesterase ABHD10, Alpha/beta hydrolase domain-containing protein 10, Abhydrolase domain-containing protein 10, Mycophenolic acid acyl-glucuronide esterase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PPK5_DERAT
Sequence: GGGGSGETSGMWFGPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-5, DerAt-Capa-PK, FXPRL-amide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.