PharMolix/UniProtQA huggingface dataset:
Protein: DNLJ_AZOVD
Sequence: MTDAQTAAERIARLRSEIDEHNYRYYVLDAPSVPDAEYDRLFNELKALEAEHPELVTPESPTQRVGGEALAAFGQVRHELPMLSLGNAFAEEDLLDFDRNVCKGLDRGIEVVEYSCEPKLDGLAVSLLYEDGQLVRGATRGDGSTGEDITANVRTVRNIPLRLHGQGWPAVLEVRGEIYMPRAGFEALNARAIENGGKTFANPRNAAAGSLRQLDPKITAGRPLEFCGYGIGRFEGAEVPQTHTSLLETLRRWGLPISRELQLARSVQDCLAYYRAIGERRQGLAYDIDGVVFKVNRLDWQRELGFRARTPHWAIAYKFPAQEELTELLGVEFQVGRTGAITPVARLKPVQVAGVTVSNASLHNMDEVARLGVMIGDTVIVRRAGDVIPQIMQVVGERRPADARPVEVPRQCPVCGSAVERTQLVKRGKGRASLSEGAIYRCVGRLACQAQLKQAIVHFVSRRAMDIDGLGERIVEQLVDTGLVKSPADLYILTFEQLVVLDGFAEVSSNNLLAAIAASRRPSLARFIYALGIPDVGEETAKRLARALGSLTRIEKALPEVLIWLPDVGLEVAHEIHSFFRDEHNLTVIGQLLARGVELQEEGELHAEFAACASLGELLDKLDIPGIAATGAKKLAEAAGSLEAVIGLSQDWLTLNTTKGLSEKARQALREFFAVPANVEHARAIEGQLREFGMHWESERRCAEGLPLAGQTWVLTGTLESMSREQGKARLESLGAKVAGSVSAKTACVVAGPGAGSKLAKAGELGVKVLDEEAFLALLRQLES
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: NAGZ_ECO7I
Sequence: MGPVMLDVEGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRELVRQIRAASRNHLVVAVDQEGGRVQRFREGFTRLPAAQSFAALLGMEEGGKLAQEAGWLMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPEKALAIASRFIDGMHEAGMKTTGKHFPGHGAVTADSHKETPCDPRPQAEIRAKDMSVFSSLIRENKLDAIMPAHVIYSDVDPRPASGSPYWLKTVLRQELGFDGVIFSDDLSMEGAAIMGSYAERGQASLDAGCDMILVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRQELMDSARWKAISARLNQLHERWQEEKAGH
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STRAB_MOUSE
Sequence: MSLLDCFCASRTRVESLRPEKQSETSIHQYLVDESAISRPPPSARASEVICSTDVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVTVKITNLESCTEERLKALQRAVILSHFFQHPNITTYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPDGMSETLIRNILFGAVQGLNYLHQNGCIHRSFKASHILISGDGLVTLSGLSHLHSLLKHGQRHRAVFDFPQFSTSVQPWLSPELLRQDLHGYNVKSDIYSVGITACELASGQVPFQDMHRTQMLLQKLKGPPYSPLDVSIFPQSDSRMRNSQSGVDSGIGESVLVSTGTHTVNSDRLHTPSTKTFSPAFFSLVQLCLQQDPEKRPSASSLLSHVFFKQMKEESQDSILPLLPPAYNRPSASLQPVSPWSELEFQFPDDKDPVWEF
What is the function of this protein?
Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1.  Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation (By similarity).
What are the official names of this protein?
STE20-related kinase adapter protein beta, STRAD beta, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein homolog, ILP-interacting protein homolog, Polyploidy-associated protein kinase, Pseudokinase ALS2CR2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: MSHR_PANON
Sequence: MSVQGPQRRLLGSLNSTSPAAPRLGLAANQTGPRCLEVSVPDGLFLSLGLVSVVENVLVVAAIAKNRNLHSPMYYFICCLAVSDLLVSVSSVLETAVMLLLEAGTLAGRAAVVQQLDDVIDVLVCGAMVSSLCFLGAIAVDRYISIFYALRYHSIVTLPRAWRAISAIWVASVLSSTLFIAYYDHTAVLLCLVSFFVAMLVLMAVLYVHMLARACQHARGIARLHKRQRPVHQGLGLKGAATLTILLGIFFLCWGPFFLHLSLMVLCPRHPICGCVFKNFNLFLTLIICNSIVDPLIYAFRSQELRKTLQEVLLCSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH (By similarity).  The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity).  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes (By similarity).
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FABPM_LOCMI
Sequence: MVKEFAGIKYKLDSQTNFEEYMKAIGVGAIERKAGLALSPVIELEVLDGDKFKLTSKTAIKNTEFTFKLGEEFDEDTLDGRKVKSIITQDGPNKLVHEQKGDHPTIIIREFSKEQCVITIKLGDLVATRIYKAQ
What is the function of this protein?
Binds fatty acids in a 1:1 molar ratio.
What are the official names of this protein?
Fatty acid-binding protein, muscle, M-FABP.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_BURCH
Sequence: MITVNVDLGDRAYPIHIGAGLIGRTELFAPHIKGSSVTIVTNTTVDPLYGDALRAALAPLGKRVSTVVLPDGEAYKNWETLNLIFDGLLTDHADRKTTLVALGGGVVGDMTGFAAACYMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQPQAVIADIGALTTLPDRELAAGVAEVIKTGAIADAGFFDWIEANVEALNRREPAALAHAVKRSCEIKASVVAADEREGGLRAILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAGDLSVRLGLLDEASRQRLDAVIAAAHLPTRGPALGDARYMDLMRVDKKAEAGAIKFILLKRFGDTLITQAPDEAVFATLAQTTR
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_NITEC
Sequence: MDKVIYPGTFDPITHGHEDLVYRASRLFGKVIVAVAVSSGKAPFFSLEERVKMARNVLTGYSNVEVTGFSGLLMEFARQQDAHIIIRGLRAVSDFEYEFQLAGMNRGLYPDVETIFLTPSEQYMFISATIVREIARLGGDVSKFVHPLVIERLRQKKIEMNNGE
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_NEIMB
Sequence: MKPVFLDFEQPIAELTNKIDELRFVQDESAVDISDEIHRLQKKSNDLTKSIFSKLTPAQISQVSRHPQRPYTLDYIEALFTDFEELHGDRHFADDYAIVGGLARFNGQSVMVVGHQKGRDTKEKIRRNFGMPRPEGYRKALRLMKTAEKFGLPVMTFIDTPGAYPGIGAEERGQSEAIGKNLYELTRLRVPVLCTVIGEGGSGGALAVALGDYVNMLQYSTYSVISPEGCASILWKTAEKAADAAQALGITADRLQKLDLVDTVIKEPLGGAHRDFGQTMKNVKAVLEKQLHEAQSIPLADLLSRRFDRIMAYGKFSEQ
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_CORDI
Sequence: MNDALADSGLVIVDKPQGMTSHDVVSKIRRTFSTKKVGHAGTLDPMATGVLVLGLERGTKFLAHMVASTKSYTATIRLGAATTTDDREGETITSASPDQLAGITETKISDAVKQFRGSIMQRPAAVSAIKIDGKRAHQRVREGEKVEIPARPVTISRYDILEIRRDAAFIDIDVEVDCSSGTYIRSLARDLGEELGVGGHLTALRRTQVGPFTLDNAVTLEKLEENPHVSLTLDQALAASYPVLSVSEKEASDLAMGKWLTPRGLKGIHAAVDPHGRAIALVKEQGKRLATIFVARPSTL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: BETA_RHIME
Sequence: MQADFVIIGSGSAGSALAYRLSEDGRNSVIVLEFGGSDVGPFIQMPAALAWPMSMNRYNWGYLSEPEPNLNNRRITAPRGKVIGGSSSINGMVYVRGHSEDFNRWEELGAQGWAYADVLPYYKRMEHSHGGEEGWRGTDGPLHVQRGPVKNPLFHAFIEAGKEAGFEVTEDYNGSKQEGFGLMEQTTWRGRRWSAASAYLRPALKRPNVELIRCFARKIVIENGRATGVEIERGGRIEVVKANREVIVSASSFNSPKLLMLSGIGPAAHLKEMGIDVKVDRPGVGQNLQDHMEFYFQQVSTKPVSLYSWLPWFWQGVAGAQWLFFKRGLGISNQFESCAFLRSAPGVKQPDIQYHFLPVAISYDGKAAAKSHGFQVHVGYNLSKSRGNVSLRSSDPKADPVIRFNYMSHPEDWEKFRHCVRLTREIFGQKAFDLYRGPEIQPGEKVQTDEEIDGFLREHLESAYHPCGTCKMGAKDDPMAVVDPETRVIGVDGLRVADSSIFPHITYGNLNAPSIMTGEKSADHILGRQPLARSNQEPWINPRWAVSDR
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: OBP70_ANOGA
Sequence: MRRQYSMWASTVAVIACGSALMLLHPVGADAPKKRCLTKPNVSKKVDMVIHQCQEEIKSSLIEDALKIFTAEHGQWHDRRKRDEGGLDFSHPTIVSHEDKWIAGCLMQCVYRKNNAIDKNGWPTLDGLVSLYTDGVNEQGYFMATLRGVDRCLKGTSKKYQIKRNDAAENFEQCEVAFDVFDCISDMITDYCSGQMEDDH
What is the function of this protein?
Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid.
What are the official names of this protein?
General odorant-binding protein 70.
What is the protein family that this protein belongs to?
Belongs to the PBP/GOBP family.
What are the subcellular locations of this protein?
Secreted.
Protein: SRP19_HALLT
Sequence: MVENVVYPAYFDADRSRSEGRRVPMDLAIEEPTVDEIAKAVQQVGYDAVIEREKTYSREFKPRGAVVVRGTEDTAKNDLVQAIAAYLGVIRE
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
What are the official names of this protein?
Signal recognition particle 19 kDa protein, SRP19.
What is the protein family that this protein belongs to?
Belongs to the SRP19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODPB_RICTY
Sequence: MQITVREALRDAMQEEMLRDDKVFVIGEEVAEYQGAYKVTQGLLEQFGSKRVIDTPITEYGFAGLAVGAAFAGLRPIVEFMTFNFAMQAFDHIVNSAAKTHYMSGGQVKCPIVFRGPNGAASRVAAQHSQNYTACYSHIPGLKVVAPYSAEDHKGLMLTAIRDDNPVIFLENEILYGHSFDVPDIIEPIPFSKAKILKEGSNVTIVTFSIQVKLALDVVNILQNDNIDCELIDLRTIKPLDTNMIIESVKKTNRLVIVEEGWFFAGVGASIASIVMKEAFDYLDAPIEIVSGKDVPLPYAVNLEKLAMPSANDLIEAVKKVCYYTI
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit beta.
Protein: UPPP_VARPS
Sequence: MDIVLLVKAAVMGIVEGLTEFLPISSTGHLILAGSLLGFDDDKAKVFDIAIQTGAIFAVILVYWQKIHSTVVALPRQAKARRLALNVVIGFLPAVVLGLLFGKMIKAHLFIPVVVASTFIIGGFIILWAEKRPPGSVRIEHVDDMTMWDALKVGLVQCFAMIPGTSRSGSTIIGGMLLGLSRQAATDFSFFLAIPTLIGAGAYSLYKERALLSVADIPLFSVGLVFSFISAWLCVRWLLKYISTHDFIPFAWYRIAFGIVVLATAWTGTVVWAE
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GSA_CORGB
Sequence: MTHMTSSNTARSAEWFEKAQKLTPGGVNSPVRAFGSVGGQARFIEKAHGSTLIDVDGNEYVDLVCSWGPMLMGHAHPAVVEAVQKAVVDGLSFGAPTIGEVELAQDIVKRTSVEEVRLVNSGTEATMSAVRLARGYTQRSKILKFEGCYHGHVDALLASAGSGVATFALPDSPGITGAQTSDTIVVPYNDIEAVRNAFAEYPGEIACIIAEAAGGNMGTVAPKDNFNDKLLAIAHADGALLILDEVMTGFRTSYRGWFGIDKVAADLVTFGKVVSGGLPAAAFGGKAEIMNMLAPQGPVYQAGTLSGNPVAVAAGRASLKLADESLYTTINANADRLHGLISDALTHEGVAHHIQRASNMLSIRFAEGEGHNFSDMKAADTFRFAPFFHTLLDNGVYAPPSVFETWFVSSALTDDDFSKIEQALKPAARAAAEAKAS
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSE_BACLD
Sequence: MFFKMLKEDVDVVFDQDPAARSYIEVILTYSGLHAIWAHRIAHALYKRKRFFIARAISQIARFFTGIEIHPGAKIGRRFFIDHGMGVVIGETCEIGNNVTVFQGVTLGGTGKEKGKRHPTIEDDALISTGAKVLGSITVGRGAKIGAGSVVLHDVPECSTVVGIPGRVVVQNGKKIRRDLNHQDLPDPVADRFRELENEIRQLKQELRRKEREDEL
What is the function of this protein?
Catalyzes the acetylation of serine by acetyl-CoA to produce O-acetylserine (OAS).
What are the official names of this protein?
Serine acetyltransferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POL2_BAYMJ
Sequence: MSASSSRQLFDCGSLDWPNKSLFGDPTTRDVMHEHISSTWNAVIRRHMLAPNADAETILGRDGLPSAQFDAYGAMLPSFIQALNAPTTRLRITHRCPTAESILCADASHAPWLYMANNVCAYEATHLKPVQTFIAFDFAHGYCYLSLFIPLSFRITFENARSFSRFLEQLPDILGAYPTLAAIYKTMLFAIRLFPEVLQAPIPIIAKRPGVLQFHVSDARGLPPSWFPMKCGSVRSFVALITNNLNSDLLDGIVGSNGDGEHYTNWNSGHDHWIVNRFITVRDLHSSLKSALDVDLDTEGGRNAVLDLLLDLGVTNLVRREKRFPAHFQGAESVYLLLSCERVGNELVAVQDALQEPLANHSGLDLRALIINLGGLPSRHSDICYTRNIFENDNHLVWNFEFYRIASITRNAQIDRDMLSSSMANLFSNFVSESSNGQYRVKEPRPIAQYRVEHDEPVASGAPSAWWQVLIGITTAILGAIIFFLWRCFLRAKRVKFQAKDSFPWFTTSGDDDSPPPPGDSPSHPPGRSPDRVLPRTVVRDLSFNDDDDLHSVDLDEAGSRFGEVVSLIARGNLRELAGAIPESLSNLTLLQTSASGSGFYTMVALYLATLGDAITAFHEHNDASPTTTQSLRTVELQLEARGLRFNEAGTPANLIQRGVNSSVGRALVRLTQSALLATGEKFRTRMATTLERIAAERLNTLTAYDQRVIEMTTELLAAIKTALEVERSELTPHLANAEALLQVYNNLFSTDYASASLLALRREMILRSAEGRVGEQPTSASDAANEELVQRSMTKLDKEIELFQAQIDSQRRAVTITEASNLRENILQPINTVANIAMAGAFLRGGARHRMPGMPDVAAPMPNPFRAFSGRGHSLTTTRSGGLFRRPRV
What are the official names of this protein?
Genome polyprotein 2.
What is the protein family that this protein belongs to?
Belongs to the bymoviruses polyprotein 2 family.
Protein: Y653_ATV
Sequence: MQPWEYVYDLLMPAGTPIGEKQFTKYIYLTLAVPATKEFEEKISKGDTKDLELPVYPVAFNTKPAEFKGDRIATKKDLLTRSGLYDDDYDFEAPIKDLEFKSALVPGYFPLAVLKLYFEGDIDAHPEDYGLKPIDGHKWYSSVNGSYKVTNGLLFNVDETKNSDHYSVLFLDENPKEFNTLNGYGVVRFYMDLKNAPPEVYTKAKEECISAGGLYYYDAREETAYCRLPLNKEANIKASEFIHQLYEMIKSKITSEDFLKNEMVYQLPGPKVIPVKPVIGKTFEEMVKTADKYLLLGETAKEETKQETKQETGKEEEEKKETKQESQEQLFNPFAIVDEMLAEGQPAEAKQENSPQQQNPPAEAKQRQQQEENNAEAPQQRQQEENTPLKMNILTEEESNKSEEGQQPLENNIQTFGFKGDIADFFASLVKDKYIFLPILSRRSPSEYKNAKKQRTFKGEAVEEHTEIPRENMKYAEFRKKYSEIVNKYAVPFMHDGIWAILPGKEQELYKELDKLVQEAQKLGISPEEIEFMVTVLLVPKDAVVREINRQIKEIRTDIDEVKQELQNPDLKKTKIASLKKQLEQKQLRLNLLKDLYSTVTKEEIDKLAGKVKDTLYTLNQIAKYAGQQEETDETTEEEEEEEEEGNDTVKLS
What are the official names of this protein?
Structural protein ORF653.
What are the subcellular locations of this protein?
Virion.
Protein: LGT_BAUCH
Sequence: MINQYLFFPNINPVLLSFGPVSIHWYGIMYLVGFWFAIWMAMRYANKPDNDWNKREIEYLLHMCFIGLLIGGRIGYVLFYNLHFFLEKPLCLFKVWDGGMSFHGGLIGVIVMIFLFSCHTQRHFFQIADVIVPLVPFGLGLGRLGNFINGELWGRVTTNTYWAMLFPGSRDADKALMLTNPQFRILFEQYGMLPRHPSQLYEMILEGIVLFCIIKIFSYKQRPMGSISGIFLICYGIFRLIVEFVRQPDAQLGLFHDMISMGQILSIPMIIAGVIILSWAYYRLT
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NU4LM_ASPNG
Sequence: MNFSIFLFLIGILGFVLNRKNIILMLISIEIMLLSITFLILISSLSFDDILGQTFAVYIITVAGAESAIGLGILVAYYRLRGSISIQYR
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: MATK_KECCO
Sequence: MEEIQRYLQLKRSQQHNFLYPLIFQEYIYAFAHDRIFSRSFLSENTGYENKSSLLIVKRLITRMYQQNPFIIFPNDSTQNQFLGHNKNFYSQLISEGFAFIVEIPFFLRLISSLEGKKKKIVKSQNLRSIHSIFPFLEDSFSHLNFVLDILIPQPVHAEILVQTLRYWVKDASSLHLIRFLLNEYCNWNSLIFPKKASSSFSNSKRNQRNQRLFLFLYNSHVCEYESIFFFLRNQSSHLRSTYSRVLLERIYFYGKIEHLVNVVVKVKDFQANLWLVKEPCMHYVRYQRKSLLASKGTSLFMNKWKCFLVTFWQWHFALWFHPRRIYINQLSKNLLEFLGYLSSVQMNPSVVRSQILENSFLINNAIKKFDTLVPIIPLIASLANTKFCNVLGHPISKPVWADLSDSHIIDRFGRICSNLSHYHSGSSKKKSLYRIKYILRLSCARTLARKHKSTVRAFLKRLGSELLEEFLMSEEDVLFLTFPKASSTLRGVYKSRIWYLDILCISDLVNYK
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: COMD7_HUMAN
Sequence: MGRLHCTEDPVPEAVGGDMQQLNQLGAQQFSALTEVLFHFLTEPKEVERFLAQLSEFATTNQISLGSLRSIVKSLLLVPNGALKKSLTAKQVQADFITLGLSEEKATYFSEKWKQNAPTLARWAIGQTLMINQLIDMEWKFGVTSGSSELEKVGSIFLQLKLVVKKGNQTENVYIELTLPQFYSFLHEMERVRTSMECFC
What is the function of this protein?
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237).  Associates with the NF-kappa-B complex and suppresses its transcriptional activity (PubMed:15799966).
What are the official names of this protein?
COMM domain-containing protein 7.
Protein: GBRL2_BOVIN
Sequence: MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVEKVSGSQIVDIDKRKYLVPSDITVAQFMWIIRKRIQLPSEKAIFLFVDKTVPQSSLTMGQLYEKEKDEDGFLYVAYSGENTFGF
What is the function of this protein?
Ubiquitin-like modifier involved in intra-Golgi traffic (PubMed:10747018).  Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation (PubMed:10747018).  It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (PubMed:10747018).  Involved in autophagy (By similarity).  Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production (By similarity).  Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity).
What are the official names of this protein?
Gamma-aminobutyric acid receptor-associated protein-like 2, GABA(A) receptor-associated protein-like 2, Ganglioside expression factor 2, GEF-2, General protein transport factor p16, Golgi-associated ATPase enhancer of 16 kDa, GATE-16, MAP1 light chain 3-related protein.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome. Endoplasmic reticulum membrane. Golgi apparatus.
Protein: MED11_BOVIN
Sequence: MATYSLANERLRALEDIEREIGAILQNAGTVILELSKEKTNERLLDRQAAAFTASVQHVEAELSAQIRYLTQVATGQPHEGSSYSSRKDCQMALKRLDYARLKLSEVARTCEQMLEN
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 11, Mediator complex subunit 11.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PCDP1_CHLRE
Sequence: MALASNPRRRLHEVRVQKYVVIAVTWRGAQPMSQRARPSRVVRAAAWGMFARCHPGAAAGWHRCTDLVTRSSARPAYTVASQSFSQGLVEDAPLQNPNTLTYNRVYSKVGNTRILQAEPAVLNFGGYELGKVYSQVLRIRNVRASGTRFHIIPPSTPFFKATCPAKKGLLAPGMTEEVAVEFCPTQYRYYYDCVRVHCEEENLLIPLHAYPVANEALFPTRVDFGRVALGQEVVRSHTLECKVPVDFEYEIVEVKPNPAFRVEPARGVVPGRGRVTVDMWFCPLALTTEEAVIETEVAGVYVPDTMLLSAAEVGLRTKDVRGAIEARKAAAAEQQAALEKGALFRLQLALAEEAARKVALGTAPHSGQQLLTAEQPELEAGGAVHQPSAPVGSSSSGGGGGSDPAFKPEHKRTRVLDKFMRAVWRVVTHQRLQRRLERIKEVLAHLGYDKQRLAEEAANPVLLVSESDRPGTAPTKYLRPEMVRVRPLPLYRDVLFQVHHATDLSHYTDFDELAPFTSKVRERLVPSGLVPPLSDYPTMPDACKNMPYITLEIGNRYGDDRVYGAPDPSYSPYGSLDVDYAVQPRQYDVYDSARHEAVASGGVRSLRGGPGLSDSWLVRQICPAVPTDEQLAKCGGTGIVNTIPN
What is the function of this protein?
May play a role in cilium morphogenesis.
What are the official names of this protein?
Cilia- and flagella-associated protein 221 homolog, Flagella-associated protein 221, Primary ciliary dyskinesia protein 1.
What is the protein family that this protein belongs to?
Belongs to the PCDP1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm.
Protein: K1328_MOUSE
Sequence: MAGAAGPFLPGSAFWSRDFSDEDQSVAYVPGISTEGNTRSRVKLINPKVDVKVKASRVTDASVSMESLKGAGDSVAEQNFCKRGMKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKTEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTLSLSELGAARAQEQQITKKKNTPQCSLMDLDGSFLSVARPQNYGQTKARPKSANQVSESFTELRNNSLRPITLHHPKEDLERMSTKTRTCTYESLGRRLINAAPIEKSLPVELKIKEYPNLPPTPSSQYCGHKCSESGAYVHENYHPTNMAPQCCKTHPESCSHCRIPWASQMHDRVILQPRETDIEKQLSEDRRQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNWLRTQAMFKSRELVADKEFPKPDLDMNGSVSGPSLWKPKCDGWMRGTSTSFKKCPDSPNSGQNQREKKTVEFQSRVENGIQWTCQQNDICRPQRETVTGVRKDASTSPMSTRSPKEPLTPASLSSQHKTSRYETSLLDLVQSLSPNSAPKSQPHPSRAAGTWSTLRPTPQKSIWKKVGTRRSPEDLEENQILEDIFFI
What is the function of this protein?
Competes with SMC1 for binding to SMC3.  May affect the availability of SMC3 to engage in the formation of multimeric protein complexes.
What are the official names of this protein?
Protein hinderin.
Protein: KTHY_ROSCS
Sequence: MSLFVTFEGPEGSGKSTQARLLYESLYARRYPVILTREPGGTRIGDLIRRIVLDLQHTEMAPTTETLLFSAARAQLVSEVIRPYLEQGGIVLCDRYADSTYAYQGYGLGRDLAELRTITAAATGGLRPDITFYLDISAEDGLERKRRKHPGARLMGQRGVDQEWNRLDARELEYHQRVEAGYRALIAQDPERWRVLDARQSIEALAEQIAAIVEPYLASIPQLEAVPYS
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: NQOR_ECOHS
Sequence: MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.