PharMolix/UniProtQA huggingface dataset:
Protein: RL5_CHLTA
Sequence: MSRLKKLYTEEIRKTLQDKFQYENVMQIPVLKKIVISMGLAEAAKDKNLFQAHLEELAVISSQKPLVTRARNSIAGFKLREGQGIGAKVTLRGIRMYDFMDRFCNIVSPRIRDFRGFSCKGDGRGCYSFGLDDQQIFPEVDLDRVKRSQGMNITWVTTAQTDAECLTLLECMGLRFKKAQ
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: PGTA_PIG
Sequence: MHGRLKVKTSEEQAEAKRLEREQKLKLYQTATQTVFQKRQAGELDESVLELTSQILGANPDFATLWNCRREVLQRLEVQKSPEELAALVKAELGFLESCLRVNPKSYGTWHHRCWLLGRLPEPNWARELELCARFLEVDERNFHCWDYRRFVASQAAVPPAEELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQPDSGPQGRLPEDVLLKELELVQNAFFTDPNDQSAWFYHRWLLGRADPQDALRCLHVSRDEACLTVSFSRPLLVGPSTETLLLMVNESPLSVEWRTPDGRNRPSHVWLCDLPAASLNDHLPQHTFRVIWTAGNAQKECVLLKGRQEGWCRDSATDEQLFRCELSVEKSTVLQSELESCKELQELEPENKWCLLTIILLMRALDPLLYEKETLQYFQTLKAVDPMRAAYLDDLRSKFLLENSVLKMEYADVRVLHLGHKDLTVLCHLEQLLLVTHLDLSHNRLRALPPALAALRCLEVLQANDNAIESLDGVTNLPRLQELSLCNNRLQQPAVLQPLASCPRLVLLNLQDNPLCQAVGISEHLAELLPSVSSILT
What is the function of this protein?
Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A.
What are the official names of this protein?
Geranylgeranyl transferase type-2 subunit alpha, Geranylgeranyl transferase type II subunit alpha, Rab geranyl-geranyltransferase subunit alpha, Rab GG transferase alpha, Rab GGTase alpha, Rab geranylgeranyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the protein prenyltransferase subunit alpha family.
Protein: CPSF7_MOUSE
Sequence: MSEGVDLIDIYADEEFNQDSEFNNTDQIDLYDDVLTAASQPSDDRSSSTEPPPPVRQEPAPKPNNKTPAILYTYSGLRSRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRANGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKRECVRVPRGGIPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPPDTYMKASTPYNHHGSRDSGPPPSTVSEAEFEEIMKRNRAISSSAISKAVSGASAGDYSDAIETLLTAIAVIKQSRVANDERCRVLISSLKDCLHGIEAKSYSVGASGSSSRKRHRSRERSPSRSRESSRRHRDLLHNEDRHDDYFQERNREHERHRDRERDRHH
What is the function of this protein?
Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs.  CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals).  Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation.  The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.  CPSF7 activates directly the mRNA 3'-processing machinery.  Binds to pA signals in RNA substrates.
What are the official names of this protein?
Cleavage and polyadenylation specificity factor subunit 7.
What is the protein family that this protein belongs to?
Belongs to the RRM CPSF6/7 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm in a transcription- and XPO1/CRM1-independent manner, most probably in complex with the cleavage factor Im complex (CFIm).
Protein: IOLG_BACVZ
Sequence: MNLRIGVIGTGAIGKEHINRITNKLSGAEITAVTDVNQEAAQQTVQDFNLNASVYPDDDSLLAAENVDAVLVTSWGPAHESSVLKAIQHGKHVFCEKPLATTAEGCMRIVEEEMKTGKRLVQVGFMRRYDSGYVQLKEAIDNRVVGEPLMIHCAHRNPTVASNYSTEMAVVDTLVHEIDVLHWLVNDDYESVQVIYPKKSKNALPHLKDPQMVIIETKGGIVINAEIYVNCKYGYDIQCEIVGEDGIIKLPEPSSISLRKEGKFSTDILMDWQRRFVAAYDVEIQDFIDSIRNKGEVSGPTAWDGYIAAVTTDACVKAQESGQKEPVALQEKPAFYQSFTTVNK
What is the function of this protein?
Involved in the oxidation of myo-inositol (MI) and D-chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively.
What are the official names of this protein?
Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase, Myo-inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase, MI 2-dehydrogenase/DCI 3-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: GBP3_HUMAN
Sequence: MAPEIHMTGPMCLIENTNGELVANPEALKILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKNKGFSLGSTVKSHTKGIWMWCVPHPKKPEHTLVLLDTEGLGDVKKGDNQNDSWIFTLAVLLSSTLVYNSMGTINQQAMDQLYYVTELTHRIRSKSSPDENENEDSADFVSFFPDFVWTLRDFSLDLEADGQPLTPDEYLEYSLKLTQGTSQKDKNFNLPRLCIRKFFPKKKCFVFDLPIHRRKLAQLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIKVNGPRLESLVLTYINAISRGDLPCMENAVLALAQIENSAAVQKAIAHYDQQMGQKVQLPAETLQELLDLHRVSEREATEVYMKNSFKDVDHLFQKKLAAQLDKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYCLFIQKLQDLEKKYYEEPRKGIQAEEILQTYLKSKESVTDAILQTDQILTEKEKEIEVECVKAESAQASAKMVEEMQIKYQQMMEEKEKSYQEHVKQLTEKMERERAQLLEEQEKTLTSKLQEQARVLKERCQGESTQLQNEIQKLQKTLKKKTKRYMSHKLKI
What is the function of this protein?
Shows the most prominent antiviral activity in epithelial cells.
What are the official names of this protein?
Guanylate-binding protein 3, GTP-binding protein 3, GBP-3, Guanine nucleotide-binding protein 3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. GB1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus membrane. Note=Heterodimers with GBP1, GBP2 and GBP5 localize in the compartment of the prenylated GBPs: with GBP1 in a vesicle-like compartment, with GBP2, around the nucleus and with GBP-5, at the Golgi apparatus.
Protein: P17_HASV
Sequence: MSEHTIAHSITLPPGYTLALIPPEPEAGWEMLEWRHSDLTTVAEPVTFGSAPTPSPSMVEETNGVGPEGKFLPLTISPLLHKTSRKALTPTPSLSPLTSLACPNSGIGPRERSTSTPIPSAGTSSTLTQRVLQSLRAPSASTRRSLTASSSSPSTQR
What are the official names of this protein?
Protein p17.
Protein: RL10_ALKEH
Sequence: MGLSLEQKKAMVQEVAAVAKEAHSAVGAEYRGLTAGQMDALRQQARENGVYLRVVKNRLAKRAVEGTEFECMQSELTGPLLLAFSLEDPGAAARVIKAYSKEHEALQTRLVAVGGQVYPASELERLASLPTREEALAMLLATMKAPVQKLATTLNEVPGKLVRTVAAVKDAKQAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: CLM7_MOUSE
Sequence: MWLSPALLLLSFPGCLSIQGPALVRGPEQGSVTVQCRYSSRWQTNKKWWCRGASWSTCRVLIRSTGSEKETKSGRLSIRDNQKNHSFQVTMEMLRQNDTDTYWCGIEKFGTDRGTRVKVNVYSVGKDTMSTSNQLPWPTVDGSTDMVSSDLQKRTYYMLLVFVKVPALLILVGAVLWLKRSTQKVPEEQWRHTLCSDLDSELLAKDISP
What is the function of this protein?
Acts as an activating immune receptor in mast cells through its interaction with ITAM-bearing adapter TYROBP.
What are the official names of this protein?
CMRF35-like molecule 7, CLM-7, CD300 antigen-like family member B, Immune receptor expressed on myeloid cells 3, IREM-3, Leukocyte mono-Ig-like receptor 5.
What is the protein family that this protein belongs to?
Belongs to the CD300 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PPDPF_SALSA
Sequence: MASIPSTGSLIATHDYYRRRIGSTSSNSSCGSSEYAGEVIPHPPGLQRQDSGHWWSSFFFPNKQNQPGGMIGSEQKSGTYTVTNGQVACIAREMVLKKQLSRQLSESSDSGKVEQGSPPPS
What is the function of this protein?
Probable regulator of exocrine pancreas development.
What are the official names of this protein?
Pancreatic progenitor cell differentiation and proliferation factor, Exocrine differentiation and proliferation factor.
What is the protein family that this protein belongs to?
Belongs to the PPDPF family.
Protein: BGLA_ASPCL
Sequence: MRFSWLEVAVTAASLANANVCIPLFPWYVSSPPFYPSPWANGQGEWAEAHQRAVEIVSQMTLTEKVNLTTGTGWMMEECVGQTGSVPRLGINWGLCGQDSPLGIRFSDLNSAFPAGINVAATWDKTLAYLRGKAMGEEFNDKGIDIQLGPAAGPLGKYPDGGRIWEGFSPDPALTGVLFAETIKGIQDAGVIATAKHYILNEQEQFRQVAEAQGYGYNITETLSSNVDDKTMHELYLWPFADAVRAGVGAIMCSYNQINNSYGCQNSQTLNKLLKAELGFQGFVMSDWSAHHSGVGAALAGLDMSMPGDISFDDGLSFWGANMTVGVLNGTIPAWRVDDMAVRIMTAYYKVGRDRLRVPPNFSSWTRDEYGYEHAAVSEGAWKKVNDFVNVQRDHAQLIREVGSASTVLLKNVGALPLTGKERKVGIFGEDAGSNPWGPNGCENRGCDNGTLAMAWGSGTAEFPYLVTPEQAIQSEVIKNGGNVFPVTHNGALTQMANIASQSSVSLVFVNADAGEGFISVDGNIGDRKNLTLWKNGEEVIKTVASHSNNTVVVIHSVGPILVDEWHDNPNITAILWAGLPGQESGNSIADVLYGRVNPSAKTPFTWGKTRESYGAPLVTKPNNGNGAPQDDFSEGVFIDYRYFDKRNETPVYEFGFGLSYTSFGYSHLRVQPLNGSTYVPATGTTGPAPAYGSIGSAADYLFPEGLKRITKFIYPWLNSTDLKASSADPNYGWEDSEYIPEAATDGSPQPILKAGGAPGGNPTLYHDLVKVSATITNTGNVAGYEVPQLYVSLGGPNEPRVVLRKFDRIHLAPGEQKVWTTTLTRRDLANWDVEAQDWVITKYPKRVYVGSSSRKLPLRAPLPRVQ
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
What are the official names of this protein?
Probable beta-glucosidase A, Beta-D-glucoside glucohydrolase A, Cellobiase A, Gentiobiase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: OPN5_HUMAN
Sequence: MALNHTALPQDERLPHYLRDGDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKHAYICLAAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIYQVIDYKFACCQTGGLKATKKKSLEGFRLHTVTTVRKSSAVLEIHEEWE
What is the function of this protein?
G-protein coupled receptor which selectively activates G(i) type G proteins via ultraviolet A (UVA) light-mediated activation in the retina (By similarity).  Preferentially binds the chromophore 11-cis retinal and is a bistable protein that displays emission peaks at 380 nm (UVA light) and 470 nm (blue light) (PubMed:22043319).  Required for the light-response in the inner plexiform layer, and contributes to the regulation of the light-response in the nerve fiber layer, via phosphorylated DAT/SLC6A3 dopamine uptake (By similarity).  Involved in local corneal and retinal circadian rhythm photoentrainment via modulation of the UVA light-induced phase-shift of the retina clock (By similarity).  Acts as a circadian photoreceptor in the outer ear, via modulation of circadian clock-gene expression in response to violet light during the light-to-dark transition phase and night phase of the circadian cycle (By similarity).  Required in the retina to negatively regulate hyaloid vessel regression during postnatal development via light-dependent OPN5-SLC32A1-DRD2-VEGFR2 signaling (By similarity).  Involved in the light-dependent regulation of retina and vitreous compartment dopamine levels (By similarity).
What are the official names of this protein?
Opsin-5, G-protein coupled receptor 136, G-protein coupled receptor PGR12, Neuropsin, Transmembrane protein 13.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HUTI_ROSDO
Sequence: MLFTNARIVTLRDDQDYGLIEEGAIATDGDQIAWVGPSADVPDAYRSETTHDLGGRLVTPALIDCHTHVVFGGNRATEFELRLNGASYEEVARAGGGIVSTVTATRGASEAALLADALTRVDALIAEGVTLIEVKSGYGLDRDTELKMLRVARQIASARPVDVRTSFLGAHAVPPEFKGNPDAYIDDICIPTLHAAHAEGLVDAVDGFCEGIAFDTAQISRVFDVAGELGLPIKLHAEQLSNIGGTQLAARYGALSADHVEYATDADAQALAKSGTVAVVLPGAFYTLRETQVPPIASFRKHAVRMALATDCNPGSSPLTSPLLAMNMACTLFRMTPLEALLGMTAHAAAALGEQDRGRIMAGARADLCVWNAQHPSELAYRIGFNPLHQRIFKGAI
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_COXBU
Sequence: MPRSTNKGPFVDHHLMKKVDQAQKEGSKRPIKTWSRRSMVVPEMVGLTIAIHNGRQHVPVYISENMVGHKLGEFAITRTFRAHSGDRKAKKEGEK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: TRPF_NITSB
Sequence: MRVKICGITNLEDALVAIEAGADALGFVFYEKSPRYIHPQEAKIISKKLPPFVERVGLFVHEEPVKIDEICSYCNMSLAQIHFDVEESFFEKLQTKALPVVRAKCAEDILQFSDRYRLVDAYVPEFGGAGRRVALEWFENIDCSKIVLAGGLSPKNVSEVKRYGFYGVDVSSGVEARKGKKDPQKVREFIQKAKFE
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: TAZF_ASPTN
Sequence: MPSNESTCLGSDRNMQTAWKLNASTPGFTPKKLRVVCIGAGLSGLTLAYKLKHERPMDFVDLRIYEKNHEVGGTWLDNVYPGVGCDIPSPSYVFPFEPNPDWSKFYVGGAEIQQYILRTTAKYGLKERIVFNTRLLKAEWNEDSAKWKLQLEQDGRVFDDETDVLINGTGCLSQWKWPDIEGLDCFKGKLLHSARWDPEYNWEGKRIAVIGNGSSALQLVPSLQPKAAKLVNYIRHPTWVSVNFCPDLTRDGMGSNFEFTEEEKQQFRDDPEMFFQYRKKVEHGVNTVLQMMISGSGEHKFLHETVEGLMRQRLADRPDLIDKMIPNYEIGCRRLSPGDGYLEALQAANARPSFANINRITPTGFETDEGEEEFDLIACATGFNTSYIPPFKMTGRGGRRLDVEWKDKPAAYFATCAAGFPNYFIFAGPNAPIGHGSVNRMIWFQADYMLNWVEKIATEDIRSVAVKDSAVRDFNEFAKENLKRFVWSKGCHAWYSKKTDGEDNIVTAMYPGSLLHFKVYLDKIRGEHFDIQYNTSNMFGFLGNGELALEREKDGDMAFYM
What is the function of this protein?
FAD-binding monooxygenase; part of the gene cluster that mediates the biosynthesis of azaterrilone A and other azaphilones, a class of fungal metabolites characterized by a highly oxygenated pyrano-quinone bicyclic core and exhibiting a broad range of bioactivities (PubMed:35398258).  The first step of the pathway begins with the non-reducing polyketide synthase tazA that assembles one acetyl-CoA starter unit, five malonyl-CoA units, and catalyzes a series of Claisen condensations, methylation, PT-mediated cyclization, and finally releases the first hexaketide precursor through the R-domain.  The tazA product then undergoes reduction on its terminal ketone and the following pyran-ring formation by yet undetermined enzyme(s).  Dehydration and enoyl reduction, possibly involving the trans-enoyl reductase tazE leads to the next intermediate.  TazD is predicted as an acetyltransferase and might catalyze the acetylation steps leading to the synthesis of azaterrilone A.  Azaterrilone A is not the final product of the taz pathway and both the highly reducing polyketide synthase tazB and the dual enzyme tazHJ catalyze late steps of the pathway, leading to the production of the 2 final stereoisomers that contain additional polyketide modification whose structures have still to be determined (Probable).
What are the official names of this protein?
FAD-binding monooxygenase tazF, Azaphilone biosynthesis cluster protein F.
What is the protein family that this protein belongs to?
Belongs to the FAD-binding monooxygenase family.
Protein: IF1_SPHAL
Sequence: MAKEELLEMRGQVVELLPNAMFRVKLENDHEILGHTAGKMRKNRIRVLVGDEVLVELTPYDLTKGRITYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGC_MYCTU
Sequence: MQNRQVANATKVAVAGASGYAGGEILRLLLGHPAYADGRLRIGALTAATSAGSTLGEHHPHLTPLAHRVVEPTEAAVLGGHDAVFLALPHGHSAVLAQQLSPETLIIDCGADFRLTDAAVWERFYGSSHAGSWPYGLPELPGARDQLRGTRRIAVPGCYPTAALLALFPALAADLIEPAVTVVAVSGTSGAGRAATTDLLGAEVIGSARAYNIAGVHRHTPEIAQGLRAVTDRDVSVSFTPVLIPASRGILATCTARTRSPLSQLRAAYEKAYHAEPFIYLMPEGQLPRTGAVIGSNAAHIAVAVDEDAQTFVAIAAIDNLVKGTAGAAVQSMNLALGWPETDGLSVVGVAP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCS2_ARATH
Sequence: MNENHIQSDHMNNTIHVTNKKLPNFLLSVRLKYVKLGYHYLISNAVYILILPVGLLAATSSSFSLTDLTLLYNHLLKFHFLSSTLFAALLIFLTTLYFTTRPRRIFLLDFACYKPDSSLICTRETFMDRSQRVGIFTEDNLAFQQKILERSGLGQKTYFPEALLRVPPNPCMSEARKEAETVMFGAIDAVLEKTGVNPKDIGILVVNCSLFNPTPSLSAMIVNKYKLRGNVLSYNLGGMGCSAGLISIDLAKQLLQVQPNSYALVVSTENITLNWYLGNDRSMLLSNCIFRMGGAAVLLSNRSSDRCRSKYQLIHTVRTHKGSDDNAFNCVYQREDNDDNKQIGVSLSKNLMAIAGEALKTNITTLGPLVLPMSEQLLFFATLVARKVFNVKKIKPYIPDFKLAFEHFCIHAGGRAVLDEIEKNLDLSEWHMEPSRMTLNRFGNTSSSSLWYELAYSEAKGRIKRGDRTWQIAFGSGFKCNSAVWRALRTIDPSKEKKKKTNPWIDEIHEFPVPVPRTSPVTSSSESR
What is the function of this protein?
Mediates the synthesis of VLCFAs from 22 to 26 carbons in length (e. g.  C22, C24, C26) (PubMed:15277688).  Involved in the elongation of C20 fatty acid suberin precursors (PubMed:18786002).  Functionally redundant with KCS20 in the two-carbon elongation of C22 fatty acids that is required for cuticular wax and root suberin biosynthesis (PubMed:19619160).
What are the official names of this protein?
3-ketoacyl-CoA synthase 2, KCS-2, Docosanoic acid synthase, Very long-chain fatty acid condensing enzyme 2, VLCFA condensing enzyme 2.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: RS12_HELP2
Sequence: MPTINQLIRKERKKVVKKTKSPALVECPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTSKFEVISYIPGEGHNLQEHSIVLVRGGRVKDLPGVKYHIVRGALDTAGVNKRTVSRSKYGTKKAKATDKKATDNKKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RPOA_STRPM
Sequence: MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLSSLPGAAVTSIKIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELEVEGPAEVTAGDILTDSDIELVNPDHYLFTIAEGHSLRATMTVAKKRGYVPAEGNKKDDAPVGTLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEHLNLFTDLTEVAKATEVMKETEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLTEKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: SYR_CHLL3
Sequence: MQSFLVAEIQNALRSASVTTGQSIIIEKPTSPKFGDYATNIAFLAAKELKRNPRQLAEELTGHFRFPEGTVTKTEVAGPGFINFFMEPAFIMQSAERVFREGAEYGKGREGQGKTAIVEYVSANPTGPLTIGRGRGGVLGDCIANLAEAQGYHVNREYYFNDAGRQMQILGESVRYRYMELCGRTIDFPDTHYKGGYIGEIAEKIHSEHGEDLLHVESIEPFRSEAESIIFSSIQKTLGRLGIVHDSFFNEHTLYTADLNGISPNQNVIDRLREKGFIGEYDGATWFLTTKLGQEKDKVLIKSSGEPSYRLPDIAYHVTKYARGFDMIINVFGADHIDEYPDVLEALKILGHDTAHVRIAINQFVTTTVNGETVKMSTRKGNADLLDDLIDDVGPDATRLFFIMRSKDSHLNFDVELAKKQSKDNPVFYLQYAHARICSLLRLAWSEIGFDAAKRPEPGVLMRLTTPEELQLAFGILDFGEASRSAFRMLEPQKMVDYMHSIAELFHRFYQECPILKAEPEIAEARLFLAVAVRQVLQNGFRILGISAPESM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_NITWN
Sequence: MRTASIKRKTKETDIEVAVNLDGSGVSEVATGIGFFDHMLDLLARHSRIDITVRADGDLHVDHHHTTEDVGIALGQAVKQALGSMVGISRYASVYMPMDETLSRVVIDISGRPVLVFKVGFPRDKIGEFDTELVREWFNAFAVNAGVTLHVETLYGENSHHIAESCFKGLARALRAAVAIDPRAANEVPSTKGQLGG
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DLAG_AMYME
Sequence: MKVSIEINGTTVSXEVXDRTL
What is the function of this protein?
Active with aldehydes and formate esters as substrates.
What are the official names of this protein?
DYE-linked aldehyde dehydrogenase, gamma chain, DL-ALDH.
Protein: AKH_MELML
Sequence: QLNYSPDW
What is the function of this protein?
This hormone, released from cells in the corpora cardiaca, causes release of diglycerides from the fat body and stimulation of muscles to use these diglycerides as an energy source during energy-demanding processes.
What are the official names of this protein?
Adipokinetic hormone, AKH.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEUD_ECO45
Sequence: MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLFNDWRFLDEKGQQPNPDFVLNFPQYQGASILLARENFGCGSSREHAPWALTDYGFKVVIAPSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKAGEKTYRFTIDAFRRHCMMNGLDSIGLTLQHDDAIASYEEKQPAFMR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: APT_PSELT
Sequence: MDLRKFIRDIPDFPFEGIIFRDVTPLLKNPQAFQAAIDKMAETVSDIDFDLIVAPEARGFIFGSALAYKLHKGFIPVRKPGKLPYETTSIEYDLEYGTAKLQIHSDAIDKGEKILLVDDVLATGGTANAIAQLVKKLGGEVAGTCFLVELTYLNPRERLRDYLIRTVISY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAEX_EDWTE
Sequence: MGTLPVMVLFGLSFPPAFFALLAALPLFWLLRRLLQPSGLYDMIWHPALFNCALYGCLFYLVSWLFI
What are the official names of this protein?
Protein AaeX.
What is the protein family that this protein belongs to?
Belongs to the AaeX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.