PharMolix/UniProtQA huggingface dataset:
Protein: PEX8_YEAST
Sequence: MFDHDVEYLITALSSETRIQYDQRLLDEIAANVVYYVPRVKSPDTLYRLVGALFRSQFIVQLPPLRLLHIVKDVFLWKLEVSEPTLPISKFYLVWNAVFESHRATWNLSQLMVLDGVLVTYPSFKQLNNAYFIDESSNKTALYYRNWKLQLFSPIWAQLWNTAIVRANLSIQHCLLIALALLFNQSNRSALLHGVDVSWNLVTEKLLDLLEEYVHGIVQPMEIFSTDSVLSTNLNHLASCLTSSITRSNEATLVNSVRKLERICRYLSDTVASLKEQQLDFKFQNVFILIILALKELSAMNMTILPNHKDTFYSMICLSLFHVHVLTQKIGTVGFPSYDYVYDNLVTYFIVMDDLSKITTVLELMKRNNTKQDPNKLVFYINFLNKITNYYGCRIRLPFITEFIEPLLHFDVFFSGKTGNTLDIEIKESIHTLTITVLSIDSSYSSQVAQWQVSRILVYLKMSMDQFIAGKLSANQILLIFGHLSTQLPSLHNYNKHLLRDSLHETYIRIVNVKNPEKKNVLIECLIVQIAFINNPHHLIGWLNICLQLINTHNKKLLQQLWEMVSSLESSLAIDWWYTTVLSSQSSKL
What is the function of this protein?
Required for peroxisome assembly.
What are the official names of this protein?
Peroxisomal biogenesis factor 8, Peroxin-8, Peroxisomal protein PAS6.
What are the subcellular locations of this protein?
Peroxisome matrix.
Protein: CREA_ASPFC
Sequence: MPPPASSMGFSDLLNPQNPESTPSTPASKSSAPSTPSTEQSNSNMASSVSLLPPLMKGARPANEEPRQDLPRPYKCPLCDRAFHRLEHQTRHIRTHTGEKPHACQFPGCTKRFSRSDELTRHSRIHNNPNSRRNNKAQHLAAAAAAAAANQDNALASNAASMMPPPSKPITRSAPVSQVGSPDISPPHSFSNYAGHMRSNLGSYARNSDRASSGMDINLLATAASQVERDEHYGFHNGPRGHHIFGSRHHNNNRLPSLSAYAISQNMSRSYSHDEDDMYSHRVKRSRPNSPNSTAPSSPTFSHDSLSPTPDHTPLATPAHSPRLRPLGTSELQLPSIRHLSLHHTPALAPMEPQPEGPNYYSPTQPHVGPSISDIMSKPDGTQRKLPVPQVPKVAVQDLLSPGFTSVSSSASNSVAGGDLADRF
What is the function of this protein?
Transcription regulator component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB.  Represses the transcription of the alcR, alcA and aldA genes by binding to a GC-rich region in their promoter.  Also plays a role in response to carbon starvation and the control of extracellular proteases activity (By similarity).
What are the official names of this protein?
Probable DNA-binding protein creA, Carbon catabolite repressor A.
What is the protein family that this protein belongs to?
Belongs to the creA/MIG C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIR1_CAPAN
Sequence: MGNLFCCVQVDQSTVAIKEQFGKYRDVLEPGCHCVPWFLGSQLAGHLSLRVQQLDVRCETKTKDNVFVNVVASIQYRALADKANEAFYKLSNTKGQIQAYVFDVIRASVPKLNLDDVFEQKNEIAKSVEEELEKAMSAYGYEIVQTLIVDIVPDEHVKRAMNEINAAARLRVAANEKAEAEKILQIKRAEGEAESKYLSGLGIARQRQAIVDGLRDSVLGFSVNVPGTTAKDVMDMVLVTQYFDTMKEIGAASKSSAVFIPHGPGAVKNVAQQIRDGLLQASVGH
What is the function of this protein?
Positive regulator of hypersensitive response (HR)-like cell death.  May be involved in potassium ion channel regulation.
What are the official names of this protein?
Hypersensitive-induced reaction 1 protein, CaHIR1, LRR1-interacting protein 3, CaLRRIP3.
Protein: Y484_MYCPN
Sequence: MGFYGNLNHMEKRKSGYVTQKQFNDFKNSNNQRLIKIENTLVSQGEQISQLIKVSILQGEQINKLTETVEKQGEQIQTQGETLKLILETLQVINKRLDRLESK
What are the official names of this protein?
UPF0134 protein MPN_484.
What is the protein family that this protein belongs to?
Belongs to the UPF0134 family.
Protein: RNT_VIBPA
Sequence: MTIENEALTLKKRFRGYFPVVVDVETAGFNAQTDALLEICAVTLRMDEEGVLHPASTIHFHIEPFEGANLEKEALEFNGIRDPFSPLRGAVSEQEALKEIYKLIRKEQKASDCSRAIMVAHNAAFDLSFVNAANERCKLKRVPFHPFATFDTATLSGLAYGQTVLAKACKTAGMEFDNREAHSALYDTQKTAELFCGIVNKWKALGGWPLVNEE
What is the function of this protein?
Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang.  Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A).  Also appears to be involved in tRNA biosynthesis.
What are the official names of this protein?
Ribonuclease T, Exoribonuclease T, RNase T.
What is the protein family that this protein belongs to?
Belongs to the RNase T family.
Protein: PLAK_XENLA
Sequence: MDLGDVVEMPMKVTEWQKTYTYDSGINSGINTSVPSLNGKMVIEDDSLAYPNSYTTVKTTTYTQQQNPDMESHLNMTRAQRVRAAMYPETVEDHSYLFSTQIEGQQTNVQKLAEPSQMLKSAIMHLINYQDDAELATRAIPELTKLLNDEDPMVVNKASMIVNQLSKKEASRKALMQSPQIVAAIVRTMQHTSDMDTARCTTSILHNLSHHREGLLSIFKSGGIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLIILGNGGPQGLVQIMRNYNYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLDNVLKILVNQLSSDDVNVLTCATGTLSNLTCNNGRNKTLVTQSNGVESLIHTILRASDKDDIAEPAVCAMRHLTSRHQDAEVAQNSVRLHYGIPAIVKLLNPPYQWPLVKATIGLIRNLALCPANHAPLYDAGVIPRLVQLLVKSHQDAQRHAASGTQQPYTDGVKMEEIVEGCTGALHILARDPVNRMDIYKLNTIPLFVQLLYSPVENIQRVSSGVLCELAQDKEAADTIDAEGASAPLMELLHSRNEGIATYAAAVLFRISEDKNADYRKRVSVELTNAIFRQDPAAWEAAQSMIPLNDPYSDEMENYRAMYPEDIPLEPMGGDMDVEYAMDGYSDHPGRGHYADNHMMA
What is the function of this protein?
Common junctional plaque protein.  The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue.  The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques.
What are the official names of this protein?
Junction plakoglobin, Desmoplakin III, Desmoplakin-3.
What is the protein family that this protein belongs to?
Belongs to the beta-catenin family.
What are the subcellular locations of this protein?
Cell junction, adherens junction. Cell junction, desmosome. Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Note=Cytoplasmic in a soluble and membrane-associated form.
Protein: ARGC_EHRCJ
Sequence: MSYQVSVAVVGATGYVGVELVRLLLAHPMVKIRYLCATQSTGKLLSSSYFHISQNYISISVSSFDDIDLDKLDVVFLCLPHGASSEIVKKIHNVVKVIDLSADFRIKDPDIYKQWYGVHYCPDLIKDFVYGLTEIYYEDIQKSSFIACPGCYPTSVLIPLFPLLRLRLVKSNNIIVDAKSGVSGAGRSVKQDNLFCEVYDAIKSYKVSNHRHIPEIEQELCFAACREDINLQFVPNLIPVKRGMMSNIYLELEVGVSLTDVREALLLFYRDSFFVVVDEEKAITTRSVVGTNYCYLGIFPGRLPNTIVIISVIDNLLKGAAGQAVQNFNVMMSYEEKLALSNIPYF
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF115_ARATH
Sequence: MANSGNYGKRPFRGDESDEKKEADDDENIFPFFSARSQYDMRAMVSALTQVIGNQSSSHDNNQHQPVVYNQQDPNPPAPPTQDQGLLRKRHYRGVRQRPWGKWAAEIRDPQKAARVWLGTFETAEAAALAYDNAALKFKGSKAKLNFPERAQLASNTSTTTGPPNYYSSNNQIYYSNPQTNPQTIPYFNQYYYNQYLHQGGNSNDALSYSLAGGETGGSMYNHQTLSTTNSSSSGGSSRQQDDEQDYARYLRFGDSSPPNSGF
What is the function of this protein?
Acts as a transcriptional activator of the phytosulfokine PSK5 peptide hormone.  Binds to the GCC-box pathogenesis-related promoter element.  Rate-limiting factor of quiescent center cell division active when surrounding stem cells are damaged.  Is a proteolytic target of APC/C-FZR1 complex.
What are the official names of this protein?
Ethylene-responsive transcription factor ERF115.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNMA_STAA3
Sequence: MSNKDIRVVVGMSGGVDSSVTAHVLKEQGYDVIGIFMKNWDDTDENGVCTATEDYNDVIEVCNQIGIPYYAVNFEKEYWDKVFTYFLDEYKKGRTPNPDVMCNKEIKFKAFLDHAMNLGADYVATGHYARIHRHEDGHVEMLRGVDNNKDQTYFLNQLSQQQLSKVMFPIGDIEKSEVRRIAEEQGLVTAKKKDSTGICFIGEKNFKTFLSQYLPAQPGDMITLDGKKMGKHSGLMYYTIGQRHGLGIGGDGDPWFVVGKNLKDNVLYVEQGFHHDALYSDYLIASDYSFVNPEDNDLDQGFECTAKFRYRQKDTKVFVKRENDHALRVTFAEPVRAITPGQAVVFYQGDVCLGGATIDDVFKNEGQLNYVV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CD2H_ASFWA
Sequence: MIIKLIFLICFKIVLSINYWVRYNDTVTLNSNINSETEGIFWNFYNNTFNTIATCGKKNNVCECSNYDKSLYNITNNCSLTIFPNNTKIFNTTYQLVYSRNRINYTINLLLPVTSPIITYNCTQSLITCEKTNGTNIHLFLNLNDTINEYTNKSFLNYYWNSSELNNIFLATCIINNTLNSANTTKVINCTNPLLKSYQNYFLENIHTLFYMIIFIVSGITISIFISIITFLSLRKRKKHVEEIESPPPESNEEEQCQHDDTTSIHEPSPREPLLPKPYSRYQYNTPIYYMRPSTQPLNPFPLPKPCPPPKPCPPPKPCPPPKPCPPPKPCPPPKPCPPPKPCPPPESYSPPKPLPSIPLLPNIPPLSTQNISLIHVDRII
What is the function of this protein?
May play an immunosuppressive role by inhibiting lymphocyte proliferation and subsequently facilitating viral replication and generalization of infection (By similarity).  Responsible for viral hemadsorption, which may help viral spread (By similarity).  Increases virus replication in the tick vector at the step of virus uptake or replication in the tick gut (By similarity).  May play a role in the host Golgi reorganization to yield viral factories (By similarity).  May play a role in host cell penetration (By similarity).
What are the official names of this protein?
CD2 homolog, CD2H, 5HL, CD2v, T-lymphocyte CD2 receptor-like protein, pEP402R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus CD2 homolog protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein. Virion membrane. Host Golgi apparatus. Note=Localizes around the cytoplasmic viral factories which are probably derived from the host Golgi membrane (By similarity). Both proteolytic fragments localize to membrane compartements (By similarity). A minor fraction localizes on the host plasma membrane and on the outer viral envelope of budding particles (By similarity).
Protein: PANB_DESHD
Sequence: MKTTKDFWVMKNEGKKIVMITAYDYPSAKQAEQAGADIILVGDSLGNVVLGYDSTVYVTMEDMIHHGKAAKRGAPNTFIVADMPFMSCHLSIRDTLLNGARLIQETGAQAVKVEGADEMIPHIKALVRAGIPVVSHLGLTPQTAAVLGGFKVQGKDGEAARKMLEDVKECQEAGAFALVLECIPKQLAQEISTTLTIPTIGIGAGVHTDGQVLVYHDILTYGVNRAPKFVKAYANADQLMLKGLQDYADEVRSMNFPDDEHSFTMKEEELKTLYGGRG
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_XANOM
Sequence: MKSIDYVNPVKNQVPKVGFVSLGCPKALVDSERILTQLRVEGYDIVPSYDAADVVVVNTCGFIDSAVTESLDAIGEAMNANGKVIVTGCLGKRPEQIREAYPQVLAVSGPQDYQSVMEAVHAALPPRHDPFVDLVPDYGIKLTPRHYAYLKISEGCNHRCSFCIIPSMRGDLVSRPVDEVLCEAERLVRGGVKELLVVSQDTSAYGVDLKYAERPWRDRMYQTRMKALCEGLSELGVWTRLHYVYPYPHVDDVLPLMAEGKLLPYLDIPFQHASPRILKLMKRPGAVEKTLQRVQRWKAMCPEITVRSTFIVGFPGETDAEFESLLDFLDQAQLDRVGAFAYSPVHGASANALPDPVPEEVKQERLARFMAKQAEISALRLEAKIGSVQQCLVDLIEDDIAVARSRADAPEIDGLVHIQNGGELGLKVGDLVDVEITDSDEHDLFGDALPANVVPQQGRALNLQMV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSH_META1
Sequence: MQDQNNSNTPKKKKLSFWGIIGIVASILVLLVIAYIIYYYVSQTTVLKRDFSFLNRAIQEAAKSATDDIYFKSIVDNPYNNSLVATMQLPENVWAALNGMTSTSTRIRVVTFEVHATTSMKNILYNEIISSIGGATPSFSRGLAMILGYSENGVTKAGEFLSTGAPTESIWSTVLRYGTNIIFLLLFAASFIFMFMSFRSQRGTGGLLDNKSVAQRIYSNKKFSDIAGNEEVKEEVKELVDYLKNPKKYSTAGARIPKGILLGGPPGTGKTLIAKATAGEANVPFFFISASNFVEMFVGLGAKRVRDMFEEARKTAPAIIFIDELDAVGRSRGAGIGGGNDEREQTLNQLLVEMDGIKENSGILIMAATNRSDVLDPALLRPGRFDRTITVGLPDIKEREAILKLHAKGKRIANNVSFMMIARRTPGFSGAQLENVINEASLLSVRENTNVITLPQLDEAIDRVMAGPAKKSRTISEKENAAVAYHEAGHAVVGIKIKGGNKVQKITIIPRGHAGGYNLMMPEEEKYNRSKAELIAIITSFMGGRVAEAIIYGKDNVSTGASDDIAKATRIARKMVTEWGLSELGPIKYEEDTDNPFLGRDYMKNASFSAQVGQEIDQEIRKIILAAEANAHKIISENRELLELIKDALIINETIVAEEIEYIAKNMKLPPAITKTKEDLHEEYSDQDFDNLFNEVSGKKIISEDKYVDDLNKEIKQLEEKIEANKSSSKSTVNEEKSKDEKNN
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: Y1261_STRP1
Sequence: MSDEKYNAKLDQAGGKLKEGFGKISGDKSLETEGKVDKVTGKVKEVIADAKDTVKGLAKGLDNKDK
What are the official names of this protein?
UPF0337 protein SPy_1261/M5005_Spy0972.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: PSD_RUMCH
Sequence: MIQIYNRKTKQYDIEQVAGGRLLNTLYTTGRGRLGLKLLVKRKIYSSLTGFFCDSKISRKTIKGFAEKFSIDTNECESKVEEFKSFNEFFARKLKPSARVFDTSEEKLLSPGDGRLQAWENIDTEKLLQIKGMTYSLSELLQDEKLAREYSGGTYLILRLCPVDYHRFHFFDSGKCMETRKIKGEYYSVNPVALSKIPELFCRNKREYSIFKTDNFGDVLFIEVGATSVGSIIQTYIPGERISKGAEKGFFKFGGSTILLIFKKNMVKIDDDIIMQTKEGFETKVLAGEAIGNCIDKRTK
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: BBS7_HUMAN
Sequence: MDLILNRMDYLQVGVTSQKTMKLIPASRHRATQKVVIGDHDGVVMCFGMKKGEAAAVFKTLPGPKIARLELGGVINTPQEKIFIAAASEIRGFTKRGKQFLSFETNLTESIKAMHISGSDLFLSASYIYNHYCDCKDQHYYLSGDKINDVICLPVERLSRITPVLACQDRVLRVLQGSDVMYAVEVPGPPTVLALHNGNGGDSGEDLLFGTSDGKLALIQITTSKPVRKWEIQNEKKRGGILCIDSFDIVGDGVKDLLVGRDDGMVEVYSFDNANEPVLRFDQMLSESVTSIQGGCVGKDSYDEIVVSTYSGWVTGLTTEPIHKESGPGEELKINQEMQNKISSLRNELEHLQYKVLQERENYQQSSQSSKAKSAVPSFGINDKFTLNKDDASYSLILEVQTAIDNVLIQSDVPIDLLDVDKNSAVVSFSSCDSESNDNFLLATYRCQADTTRLELKIRSIEGQYGTLQAYVTPRIQPKTCQVRQYHIKPLSLHQRTHFIDHDRPMNTLTLTGQFSFAEVHSWVVFCLPEVPEKPPAGECVTFYFQNTFLDTQLESTYRKGEGVFKSDNISTISILKDVLSKEATKRKINLNISYEINEVSVKHTLKLIHPKLEYQLLLAKKVQLIDALKELQIHEGNTNFLIPEYHCILEEADHLQEEYKKQPAHLERLYGMITDLFIDKFKFKGTNVKTKVPLLLEILDSYDQNALISFFDAA
What is the function of this protein?
The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia.  The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.  This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome.  Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane.  Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane.  The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation.  Required for proper BBSome complex assembly and its ciliary localization.
What are the official names of this protein?
Bardet-Biedl syndrome 7 protein, BBS2-like protein 1.
What are the subcellular locations of this protein?
Cell projection, cilium membrane. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton, cilium basal body.
Protein: DLO1_ARATH
Sequence: MATSAISKLLVSDFASSVHIPSNYVRPISDRPNLSEVESSGDSIPLIDLRDLHGPNRAVIVQQLASACSTYGFFQIKNHGVPDTTVNKMQTVAREFFHQPESERVKHYSADPTKTTRLSTSFNVGADKVLNWRDFLRLHCFPIEDFIEEWPSSPISFREVTAEYATSVRALVLRLLEAISESLGLESDHISNILGKHAQHMAFNYYPPCPEPELTYGLPGHKDPTVITVLLQDQVSGLQVFKDDKWVAVSPIPNTFIVNIGDQMQVISNDKYKSVLHRAVVNTENERLSIPTFYFPSTDAVIGPAHELVNEQDSLAIYRTYPFVEYWDKFWNRSLATASCLDAFKAPTT
What is the function of this protein?
(Microbial infection) Confers susceptibility to the downy mildew pathogen Hyaloperonospora arabidopsidis.
What are the official names of this protein?
Protein DMR6-LIKE OXYGENASE 1, 2-oxoglutarate (2OG)-Fe(II) oxygenase-like protein DLO1, Protein SENESCENCE-ASSOCIATED GENE 108, Salicylate 3-hydroxylase DLO1, S3H DLO1, SA 3-hydroxylase DLO1, Salicylic acid 3-hydroxylase DLO1.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: CH60_BACSU
Sequence: MAKEIKFSEEARRAMLRGVDALADAVKVTLGPKGRNVVLEKKFGSPLITNDGVTIAKEIELEDAFENMGAKLVAEVASKTNDVAGDGTTTATVLAQAMIREGLKNVTAGANPVGVRKGMEQAVAVAIENLKEISKPIEGKESIAQVAAISAADEEVGSLIAEAMERVGNDGVITIEESKGFTTELEVVEGMQFDRGYASPYMVTDSDKMEAVLDNPYILITDKKITNIQEILPVLEQVVQQGKPLLLIAEDVEGEALATLVVNKLRGTFNAVAVKAPGFGDRRKAMLEDIAVLTGGEVITEDLGLDLKSTQIAQLGRASKVVVTKENTTIVEGAGETDKISARVTQIRAQVEETTSEFDREKLQERLAKLAGGVAVIKVGAATETELKERKLRIEDALNSTRAAVEEGIVSGGGTALVNVYNKVAAVEAEGDAQTGINIVLRALEEPIRQIAHNAGLEGSVIVERLKNEEIGVGFNAATGEWVNMIEKGIVDPTKVTRSALQNAASVAAMFLTTEAVVADKPEENGGGAGMPDMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDCS_STAAM
Sequence: MAYFNQHQSMISKRYLTFFSKSKKKKPFSAGQLIGLILGPLLFLLTLLFFHPQDLPWKGVYVLAITLWIATWWITEAIPIAATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFILAIAMERWNLHTRVALTIINLIGASTSKILLGFMVATGFLSMFVSNTAAVMIMIPIGLAIIKEAHDLQEANTNQTSIQKFEKSLVLAIGYAGTIGGLGTLIGTPPLIILKGQYMQHFGHEISFAKWMIVGIPTVIVLLGITWLYLRYVAFRHDLKYLPGGQTLIKQKLDELGKMKYEEKVVQTIFVLASLLWITREFLLKKWEVTSSVADGTIAIFISILLFIIPAKNTEKHRRIIDWEVAKELPWGVLILFGGGLALAKGISESGLAKWLGEQLKSLNGVSPILIVIVITIFVLFLTEVTSNTATATMILPILATLSVAVGVHPLLLMAPAAMAANCAYMLPVGTPPNAIIFGSGKISIKQMASVGFWVNLISAIIIILVVYYVMPIVLGIDINQPLPLK
What is the function of this protein?
Mediates the transport of the dicarboxylates fumarate, malate, and succinate across the cytoplasmic membrane via a Na(+)-electrochemical gradient.  Transports 2 Na(+) for each dicarboxylate.
What are the official names of this protein?
Sodium-dependent dicarboxylate transporter SdcS, Na(+)/dicarboxylate symporter.
What is the protein family that this protein belongs to?
Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CERT_MOUSE
Sequence: MSDNQSWNSSGSEEDPETESGPPVERCGVLSKWTNYIHGWQDRWVVLKNNTLSYYKSEDETEYGCRGSICLSKAVITPHDFDECRFDISVNDSVWYLRAQDPEHRQQWVDAIEQHKTESGYGSESSLRRHGSMVSLVSGASGYSATSTSSFKKGHSLREKLAEMETFRDILCRQVDTLQKYFDVCADAVSKDELQRDKVVEDDEDDFPTTRSDGDFLHNTNGNKEKLFPHVTPKGINGIDFKGEAITFKATTAGILATLSHCIELMVKREESWQKRHDREVEKRRRVEEAYKNVMEELKKKPRFGGPDYEEGPNSLINEEEFFDAVEAALDRQDKIEEQSQSEKVRLHWPTSLPSGDTFSSVGTHRFVQKPYSRSSSMSSIDLVSASDDVHRFSSQVEEMVQNHMNYSLQDVGGDANWQLVVEEGEMKVYRREVEENGIVLDPLKATHAVKGVTGHEVCNYFWNVDVRNDWETTIENFHVVETLADNAIIVYQTHKRVWPASQRDVLYLSAIRKIPALTENDPETWIVCNFSVDHDSAPLNNRCVRAKINIAMICQTLVSPPEGDQEISRDNILCKITYVANVNPGGWAPASVLRAVAKREYPKFLKRFTSYVQEKTAGKPILF
What is the function of this protein?
Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.
What are the official names of this protein?
Ceramide transfer protein, CERT, Collagen type IV alpha-3-binding protein, Goodpasture antigen-binding protein, GPBP, START domain-containing protein 11, StARD11, StAR-related lipid transfer protein 11.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus. Endoplasmic reticulum. Note=Preferentially localized to the Golgi apparatus.
Protein: URE2_MICLC
Sequence: MKPGEYVLADAPVVCNRGREAVELSVTNRGDRPVQVGSHFHFAEANRALDFDRQAALGCRLDIPAGTAVRLEPGDETTVKLIPLGGDRVVYGFRDMVDGSLDPHEAAGLHAAPAAPAIPARHESAAGDAPSPLKERAGFDNETR
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPSD_MOUSE
Sequence: MNGTEGPNFYVPFSNVTGVVRSPFEQPQYYLAEPWQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVVFTWIMALACAAPPLVGWSRYIPEGMQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIFFLICWLPYASVAFYIFTHQGSNFGPIFMTLPAFFAKSSSIYNPVIYIMLNKQFRNCMLTTLCCGKNPLGDDDASATASKTETSQVAPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  Required for photoreceptor cell viability after birth (PubMed:9020854).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (PubMed:27353443).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: IOLE_HALH5
Sequence: MADQKILWGIAPIGWRNDDIPEIGAGNTLSHLLSDIVVARFQGTEVGGFFPDAKTLNKELELRNLKIAGQWFSSYLIRDPFESVSKEFHAHCAYLEEVGASVAVVSEQTYSIQQSEQNIFTEKPMFTDSEWLTLCEGLNELGKIAQQYGLTLVYHHHMGTGVQTLAEVDRLMENTDPTLVSLLYDTGHIYVSDNDYMLLLTKHLDRIKHVHFKDVRSDILAKCQEQGQSFLQSFLAGMFTVPGDGCIDFTKVYDVLLTHDYRGWIVVEAEQDPAKAHPLEYALKARQYIDEKLLTTDEMKERI
What is the function of this protein?
Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).
What are the official names of this protein?
Inosose dehydratase, 2-keto-myo-inositol dehydratase, 2KMI dehydratase.
What is the protein family that this protein belongs to?
Belongs to the IolE/MocC family.
Protein: RSMJ_PSEPG
Sequence: MEEQGTGIRVEALSAEFAAQAAAWAERLELPLHDEAADFAVQVGADGLQIQQLGPQAPGPVRVDFVEGQAAHRRQFGGGNGQMIAKAVGIAQGVRPQVLDATAGLGKDAFVLASLGCQMTLIERQPLIAALLEDGLARARADEEVGAIVGRMRLLTGNAIERMRAWEGEPPQVIYLDPMFPHRDKSALVKKEMRVFRPLVGDDLDAPALLEAALALASHRVVVKRPRKAPIIDGPKPSHSLEGKSSRYDIYPKKALKA
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_RICCN
Sequence: MTIQYTFSMIKPDAIKRNKIGQVNTYLENAGLKIVAQKMKFLTKYEAACFYDEHRARPFFNSLVEYITSGAVVLQVLKGEDAITLNRTVMGATNPAEAEAGTIRKDLGESIEANSIHGSDSENSAKREIEFFFNKSEIIE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.