PharMolix/UniProtQA huggingface dataset:
Protein: LCA5L_MOUSE
Sequence: MRLWTMSLADTTEAHTNEHFPSLALGSNKKSTEGKRSPGAGGQSQNSQASNGSVDYSRSQCSCTSLTSHYDYSEDFLSDCSETAVRRLQSEKPLAKAKEKRKYNAGKLPQPRGQKDIPAEKKQFWNASLISSQIQTIAKRRDTMTHRILSARLHKIKELKNELADVHRKLEASAIENQFLKQLQLRHLKAIGKYVNSQNNLPQITAKHQNEVKNLRQLLRKSQEKERAVSRKLRETDGELLRTKDVLQALQRLSEDKNLAEREELTDRLTDLTAKMEANDKKIQNLEKQLRLNNRSYSRQLAKENRKTLAAQTATKTLQAEVRQLQQKLKEKDRELEIKNIYTNRILKNLNDKEDYPKVSSTKSVQADRKSLPSVNMRHQETQKSDVPFWITKGKRGKGNIAHKEKSTETNHDIPYYVCKLPKQEESKRKYEANLTVLKSMPSPPASWGLVATEQICAFHLECHSCTHTADLSKEVEHRKPQTSLETPRRPKENKEDQEKRAIPAEAEPTAKESEAHKDAEDKALTRAAGNAGDAGDAGDAGNDREVVGEHKVVGAQEVVGAQELPGADEADEVHGAGEAPRDVEPGRGRRKTPRKHYSFTEATENLHHGLPTSCRQVSGSPHCRCRHDMGKHRSEQELRLEPAGYEPSFGKGAGARARARARATAFRDRKSSLMEELFGAGFAGRAGSSDSEAVSKSPQTGPQASAGNAFGDSRATVAGSIQASPTEANRKTVV
What are the official names of this protein?
Lebercilin-like protein, Leber congenital amaurosis 5-like protein.
What is the protein family that this protein belongs to?
Belongs to the LCA5 family.
Protein: LPXD_NOSS1
Sequence: MKFSDIISKLEVTNHSLTQNPNNDPEITGMAAIDEATSANLSYIEGAKFASFIAQTNASALILPQNEAMQAQAQARGIVWMTTPEPRLLFAKAIALFYQPYTPTPEIHPTAVIHPTAKIGNDVYIGPHVVIQPGVEIGNGVIIHPNVVIYPYVKIGDRSILHANCTIEERSQIGADCIIHSGAVIGGEGFGFVPTRTGWYKMEQSGYVVLEDRVDIGCNTTIDRPSVGETRVGYDTKIDNLVQIAHGCQIGAGCAIAAQTGMAGGVKLGKRVILAGQVGIANQAKMGDGSTASAQTGILHDVKPGEVVSGTPAIPHKIYLKIGAIYSRLPEMYQAFRQLQRQSDKESKR
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: RS18_STRP4
Sequence: MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKILPRRVTGTSAKNQRKVTXAIKRARVMALMPFVNED
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: SCO2A_MOUSE
Sequence: MAALRLLAWALPRGVSALRPPPALPHRLIRRYVSDRSGSVHFYTDPVKAVEGVKDGSTVMLGGFGLCGIPENLIGALKTKGVKDLKIVSSNVGVDDFGLGILLASKQVRRVVCSYLGENALCEKLYLAGELELEMTPQGTLAERIRAGGTGVPAFYTPTGYGTLVQEGGSPIRYAPDGHLITLSEPREVREFQGRFYLLEHAIRADFALIKGWKADRSGNVIFRGSARNFNVPMCKAADISVVEVEEIVDVGTFAPEDIHVPNIYVDRVIKGPKFEKRIERLTTRDSKPAPGSKDNDPSRTRIIKRAALEFQDGMYANLGIGIPVLASNYISPKMTVYLHSENGILGLGPFPLKNEVDADVINAGKQTVTVVPGGCFFASDDSFAMIRGGHLQLTMLGAMQVSQYGDLANWMVPGKKVKGMGGAMDLVSSKKTRVVVTMEHCTKTKQPKILKKCTMPLTGKRCVDLIITEKAVFEVNHSKGLTLVELWEGSSVDDIKATTACSFAVSPNLKPMQQIKLDA
What is the function of this protein?
Key enzyme for ketone body catabolism.  Transfers the CoA moiety from succinate to acetoacetate.  Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate (By similarity).  Probably play and important roles in the energy metabolism of spermatozoa.
What are the official names of this protein?
Succinyl-CoA:3-ketoacid coenzyme A transferase 2A, mitochondrial, 3-oxoacid CoA-transferase 2A, Testis-specific succinyl-CoA:3-oxoacid CoA-transferase 1, SCOT-t1.
What is the protein family that this protein belongs to?
Belongs to the 3-oxoacid CoA-transferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CHED_CAUSK
Sequence: MMGQAHAEDSGPAIKVHVTQGESHVSADPQVVMTTVLGSCIAACLRDPTTGIGGMNHFLLPDSGDRKDGGDAVRYGAYAMELLINGLLKKGARRDRLEAKIFGGGKLFDGLSDVGASNAAFAERFLRDEGIPIVSSSTGGLSARRVEFWPASGRVRQRLVAVDNAPAEVRRPTPAVAPTANSGDLELF
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: MUTX_STRR6
Sequence: MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAVREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGMLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE
What is the function of this protein?
Involved in the DNA repair system to avoid A. T to G. C transversions.  Degrades 8-oxo-dGTP to the monophosphate, but is also active on all of the nucleoside triphosphates (By similarity).
What are the official names of this protein?
8-oxo-dGTP diphosphatase, 8-oxo-dGTPase, 7,8-dihydro-8-oxoguanine-triphosphatase, Mutator protein MutT, dGTP pyrophosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: IFEA_ASCSU
Sequence: MSDLNDRLASYIEKVRFLEAQNRKLAADLDLLRGRWGKDTLSVRAMYEGELQEARKLVNDTNRQREELEKEIRKLLDELSEYRRKYEDALRGHQIDRDRIDELLNQLSGLEAEINLLRRRIANIIEEIARIKKENLQFANELTKARSDLDQETLNRIDFQNQVQTLLEEIDFMRRVHDQEIAELQAMASRDTTPENREYFKNELASAIRDIRAEYDQICNVNRMDMESWYKLKVQEIQTQSTRQNLEQNYAKKRLRVQLTDLRGKLADLEGRNSLLKQTQELNYQLEDDQRSYEAALNDRDAQIRKMDEECQALMMLLDTKQTLDAEIAIYRKMLEGEENRAGLRQLVEQVVKTHGLTQVDETESLRVLKGETASRTSFQRSAKGNVSIQETAPDGRYVVLENTHRSKEEAIGEWKLKRKIDGKREIVYTLPRDFILRPGKSVKIWARGQGGIHSPPEQLVFDLEDTFGSGSNVQTILFNREGEERATHIQRSSHTI
What are the official names of this protein?
Intermediate filament protein A, IF-A.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP5E_PICAN
Sequence: SSWQKAGISFNKYLAIAARTVQRSLKNDLKVAAEKRYISDAKVQKLEKGNVVSTTDLASNKSA
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:25759169).  F-type ATP synthases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk (PubMed:27791192).  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity).  Part of the complex F(1) domain and the central stalk which is part of the complex rotary element (By similarity).  Rotation of the central stalk against the surrounding alpha/ATP1(3)beta/ATP2(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta/ATP2 subunits (By similarity).
What are the official names of this protein?
ATP synthase subunit epsilon, mitochondrial, ATPase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ATPase epsilon family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Note=The F-type ATP synthase complex is anchored in the mitochondrial inner membrane via the F(0) domain with the F(1) domain and the peripheral stalk extending into the mitochondrial matrix.
Protein: GLPK_BORPA
Sequence: MTANEFILALDQGTTSSRAIVFDRAGTVRGMGQREFRQHYPRPGWVEHDAGEIWQSQLEVAREALRNAGASAADLAALGITNQRETTLIWERATGRPLARAIVWQDRRTAAMCEKLLHDGHGRMLQERTGLVVDAYFSGTKLAWLLDHVPGARKMAERGELAFGTVDTWLVWQLTGGAVHSTDPSNASRTMLFDLHAQDWSDDILALLNIPRGILPRIAPSSARIGETLPEWLGGSIPIAGVAGDQQAATFGQACFTPGMAKNTYGTGCFMLMNVGDAPVASRHNLLSTVGWSLPAGNATHATYMVEGGVFMAGAAVQWLRDGLGIIQRSADIEALAASVADTDDVFMVPAFAGLGAPHWDPYARGTLVGMTRGTTRAHIARATLESIALQSAELLSCMNADSGIPLSELRVDGGAARNDLLMQMQADLLGVPVVRPRVPESTALGAAGLAGLAVGFWSSLDEFGAQWQAERTFEPAWPADVREARMQRWRQAVELSKGWSRPAAGHA
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: CHEV_BACSU
Sequence: MSLQQYEILLDSGTNELEIVKFGVGENAFGINVMKVREIIQPVEVTSVPHSHQHVEGMIKLRGEILPVISLFSFFGVEPEGSKDEKYIVTEFNKRKIVFHVGSVSQIHRVSWEAIEKPTSLNQGMERHLTGIIKLEDLMIFLPDYEKIIYDIESDSGVDTYNMHTEGFDERRTDKKLIIVEDSPLLMRLLQDELKEAGYNNIASFENGKEAYEYIMNLAENETDLSKQIDMIITDIEMPKMDGHRLTKLLKENPKSSDVPVMIFSSLITDDLRHRGEVVGADEQISKPEISDLIKKVDTYVIE
What is the function of this protein?
Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors.  Chemotaxis involves both a phosphorylation-dependent excitation and a methylation-dependent adaptation.  CheV and CheW are involved in the coupling of the methyl-accepting chemoreceptors to the central two-component kinase CheA; they are both necessary for efficient chemotaxis.  Moreover, CheA-dependent phosphorylation of CheV is required for adaptation to attractants during B. subtilis chemotaxis.
What are the official names of this protein?
Chemotaxis protein CheV.
Protein: NU4C_ATRBE
Sequence: MNYFPWLTIIVVFPIFAGSLIFFLPHKGNRVIRWYTICICILELLLTTYAFCYHFQLDDPLIQLVEDYKWIDFFDFHWRLGIDGLSIGPILLTGFITTLATLAAWPITRDSRLFHFIMLAMYSGQIGSFSSRDLLLFFIMWELELIPVYLLLAMWGGKKRLYSATKFILYTAGGSVFLLMGVLGVALYGSNEPTLNFETLVNQSYPVVLEIIFYIGFFIAFAVKLPIIPLHTWLPDTHGEAHYSTCMLLAGILLKMGAYGLIRINMELLPHAHSIFSPWLMIIGTIQIIYAASTSLGQRNLKKRIAYSSVSHMGFIIIGISSLTDTGLNGALLQIISHGFIGAALFFLAGTTYDRIRLVYLDEMGGIAIPMPKMFTMFSSFSMASLALPGMSGFVAELIVFFGIITGQKYVLIPKILITFVMAIGMILTPIYSLSMSRQMFYGYKLFNAPKDSFFDSGPRELFLSISIFLPVIGIGIYPDFVLSLAVDKVEVILSNFFYR
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4, chloroplastic, NAD(P)H dehydrogenase, chain 4, NADH-plastoquinone oxidoreductase chain 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: J_BPPHM
Sequence: MKRKPMSRKASQKTFKKNTGVQRMNHLNPRAMRGGIRL
What is the function of this protein?
Mediates ssDNA packaging into virion, it locates to the internal surface of the capsid, thereby displacing the internal scaffolding protein VP3 during virion formation.  Additionally, protein VP8 plays a role in viral attachment to the host cell (By similarity).
What are the official names of this protein?
DNA binding protein VP8.
What is the protein family that this protein belongs to?
Belongs to the microviridae J protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: NUSB_BURP6
Sequence: MKKSARRQSRELATQGLYQWLLSNAAPGEIDAQLRGALGYDKADKTLLDTILHGVIREHATLAEAISPSLDRPIDQLSPVERAVLLIATYELTHQIETPYRVIINEAVELAKTFGGSDGYKYVNGVLDKLAVKLRPAETQARRGA
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: RL2_SODGM
Sequence: MAIVKCKPTSPGRRHVVKVVNPELHKGKPYAPLLETLSKSGGRNNNGRITTRHIGGGHKQHYRLIDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGEQIQSGVDAAIKAGNALPMRNIPVGSTVHNVEMKPGKGGQLARSAGAYVQIVARDGAYVTLRLRSGEMRKIQSECRATLGEVGNAEHMLRVLGKAGASRWRGIRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGIQTKGKKTRSNKRTDKFIVRRRSK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: Y1504_ARCFU
Sequence: MLYMDDECQKLLAEKEAIIRELQEKVKELEAKLKSYEIREVYKGIIPDDVLEEFVKLPPEQMIIEIGRYLREKGSTGQVEAKKTVNDVRQEIASVEEEVSKAEKEIEKTISTITGAAKTKVGVDLTFTQKYDYEGSDVAFLAEDIMNAIGVKEGEYVSVKKNGTVNLRVLPYSKEGFIVVPTWVREKLGVKVNDFVEVVRR
What are the official names of this protein?
Uncharacterized protein AF_1504.
Protein: RF1_YERPN
Sequence: MKSSIVAKLEALQERHEEVLAYLGDASVIADQDRFRALSREYAQLTDVTRCFKEWRSAQDDIEAAEMMLDDLEMREMAQEELKIAKARSEELEQQLQVLLLPKDPDDERDCFLEIRAGTGGDEAAIFAGDMFRMYSRYAETRRWKVEIMSASEGEHGGYKEIIAKISGDGVFGQLKFESGGHRVQRVPETESQGRIHTSACTVAVMPAIPEAELPEINAGDLRIDTFRSSGAGGQHVNTTDSAIRITHIPTGIVVECQDERSQHKNKAKAMSVLGARIRAAEMQKRQLAEASERRNLLGTGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEVMEGKLDMLIQPIVQEYQADQLSALSEQD
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNS3_PYRPY
Sequence: MVHVVMMVFLLIVLILCSSTVGYDYFQFTQQYQLAVCNSNRTLCKDPPDKLFTVHGLWPSNMVGPDPSKCPIKNIRKREKLLEHQLEIIWPNVFDRTKNNLFWDKEWMKHGSCGYPTIDNENHYFETVIKMYISKKQNVSRILSKAKIEPDGKKRALLDIENAIRNGADNKKPKLKCQKKGTTTELVEITLCSDKSGEHFIDCPHPFEPISPHYCPTNNIKY
What is the function of this protein?
Self-incompatibility (SI) is the inherited ability of a flowering plant to prevent self-fertilization by discriminating between self and non-self pollen during pollination.  In many species, self-incompatibility is controlled by the single, multiallelic locus S.
What are the official names of this protein?
Ribonuclease S-3, S3-RNase.
What is the protein family that this protein belongs to?
Belongs to the RNase T2 family.
Protein: DEOD_SHIBS
Sequence: MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVLPHVKLRDVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGIDARVGNLFSADLFYSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAERQTTFNDMIKIALESVLLGDKE
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: NU4LM_VAMPU
Sequence: MSLTYMNMFMAFTISLLGLLMYRSHMMSSLLCLEGMMLSLFVMMTMVILNTHLTLASMIPIILLVFAACEAALGLSLLVMVSTTYGMDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL20_RICB8
Sequence: MTRAKSGKISKNRHKKILKLAKGYRGRASTCFRVAIEKVEKGLQYAYRDRRNRKRDFRGLWIQRINAAVREHGLVYSQFMGALKKAEIDIDRKVLAELAVNNNEEFASIVEQAKAHI
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: G6PC2_MOUSE
Sequence: MDFLHRSGVLIIHHLQEDYRTYYGFLNFMSNVGDPRNIFSIYFPLWFQLNQNVGTKMIWVAVIGDWFNLIFKWILFGHRPYWWIQETEIYPNHSSPCLEQFPTTCETGPGSPSGHAMGSSCVWYVMVTAALSYTISRMEESSVTLHRLTWSFLWSVFWLIQISVCISRVFIATHFPHQVILGVIGGMLVAEAFEHTPGVHMASLSVYLKTNVFLFLFALGFYLLLRLFGIDLLWSVPIAKKWCANPDWIHIDSTPFAGLVRNLGVLFGLGFAINSEMFLRSCQGENGTKPSFRLLCALTSLTTMQLYRFIKIPTHAEPLFYLLSFCKSASIPLMVVALIPYCVHMLMRPGDKKTK
What is the function of this protein?
May hydrolyze glucose-6-phosphate to glucose in the endoplasmic reticulum.  May be responsible for glucose production through glycogenolysis and gluconeogenesis (By similarity).
What are the official names of this protein?
Glucose-6-phosphatase 2, G-6-Pase 2, G6Pase 2, Islet-specific glucose-6-phosphatase catalytic subunit-related protein.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphatase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PSF2_EMENI
Sequence: MAFPLPRGITPPEISFLAEMELVTIVPRQRLEGLELLGGPVAPLIPPRRTNVPLWLALLLKRQRRANILPPPWLHPESLSLILDIETRDQAYQHAFSPPPPLPGQPSLRERSYKKSTARPRFTPEGTKYYATPPFLPQNVAQDQAFDAFESEPPTLPFHWLEVGTMLLDAAADDLVDPDQTRRLLKELREVRSAKIRSGVEVLDDAAGPGGGVALTGVGAMEIGEGRGFISGVVDGLRRIGASKEQARREQLADATNREYDDMQDYNDEMEF
What is the function of this protein?
The GINS complex plays an essential role in the initiation of DNA replication.  Has a role in chromosome segregation (By similarity).
What are the official names of this protein?
DNA replication complex GINS protein psf2.
What is the protein family that this protein belongs to?
Belongs to the GINS2/PSF2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUOI_NOCSJ
Sequence: MAGSPEPKSMREQFWDPIAGFGVTFRTMFKKVVTEQYPFDKYPTAPRFHGRHQLNRWPDGLEKCVGCELCAWACPADAIYVEGASNSDDPDGGERFSPGERYGRVYQINYLRCILCGLCIEACPTRALTMTNEYELADDNRADLIYEKSDLLAPLLPGMEQPPHPMRLGDDEGAYYRGEFAAPAPTAPGSSTEAGA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL22_SHEON
Sequence: MEVLAKHRFARTSAQKARLVADQIRGLPVAKALEILTFSPKKAAVLVKKVLDSAIANAEHNEGADIDELKVGAVFVDEGPTMKRIMPRAKGRADRIMKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: SL7_DABSI
Sequence: MGRFISISFGLLVVFLSLSGTGAKQDCLSDWSFYEGYCYKVFNEKKTWEDAEKFCNEQVNGGYLVSFRSSEEMDFVIRMTFPIFRFDFFWIGLRDFWRDCYWRWSDGVNLDYKAWSREPNCFVSKTTDNQWLRWNCNDPRYFVCKSRVSC
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec 7, C-type lectin-like 7.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: COA6_SCHPO
Sequence: MAGNGALRRSAREKCWEARDAYFGCLDRHSILDGLKDDTKAAQACSAEKTAFETDCVKSWVNYFLKFRVQQHQQQEAIKKLEAQGAKKLN
What is the function of this protein?
Involved in cytochrome c oxidase complex assembly and is required for efficient formation of respiratory supercomplexes comprised of complexes III and IV.
What are the official names of this protein?
Cytochrome c oxidase subunit 6B-like protein new16.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 6B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion intermembrane space.
Protein: EPS8_RAT
Sequence: MNGHMSNHSSGYGIYPSQMNGYGSSPPYSQMDREHCSRTSAKALYEQRKNYARDSVSSVSDVSQYRVEHLTTFVLDRKDAMITVDDGIRKLKLLDAKGKVWTQDMILQVDDRAVSLIDLESKNELENFPLNTIQHCQAVAHTCSYDSILALVCKEPTQNKPDLHLFQCDEVKANLISEDIESAISDSKGGKQKRRPEALRMIAKADPGIPPPPRAPAPVPPGTVTQVDVRSRVAAWSAWAADQGDFEKPRQYHEQEETPEMMAARIDRDVQILNHILDDIEFFITKLQKAAEAFSELSKRKKSKKSKRKGPGEGVLTLRAKPPPPDEFVDCFQKFKHGFNLLAKLKSHIQNPSASDLVHFLFTPLNMVVQATGGPELASSVLSPLLTKDTVDFLNYTVKAEERQLWMSLGETWMKVRAEWPKEQFIPPYVPRFRNGWEPPMLNFMGAPTEQDMYQLAESVANAAEQQRKQDSKRQSTEHSSMSDYPPADGYTFSNSMYHRGPHVDQGEAALALKSTPNRHVDRNYDPVKTQPKKYAKSKYDFVARNSSELSVMKDDVLEILDDRKQWWKVRNASGDSGFVPNNILDIMRTPESGVGRTDPPYTHTIQKQRTEYGPRSADTPSAPSPPPTPAPVPVPLPPSAPAPVPVPKVPANVTRQNSSSSESGGSIARDSQRYKQLPVDRRKSQMEEVQDELFQRLTIGRSAAQRKFHVPRQNVPVINITYDSSPEEVKTWLQSKGFNPVTVSSLGVLNGAQLFSLNKDELRSVCPEGARVFSQITVQKAALEDSSGSSELQEIMRRRQEKISAAASDSGVESFDEGSSH
What is the function of this protein?
Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture.  Depending on its association with other signal transducers, can regulate different processes.  Together with SOS1 and ABI1, forms a trimeric complex that participates in transduction of signals from Ras to Rac by activating the Rac-specific guanine nucleotide exchange factor (GEF) activity.  Acts as a direct regulator of actin dynamics by binding actin filaments and has both barbed-end actin filament capping and actin bundling activities depending on the context.  Displays barbed-end actin capping activity when associated with ABI1, thereby regulating actin-based motility process: capping activity is auto-inhibited and inhibition is relieved upon ABI1 interaction.  Also shows actin bundling activity when associated with BAIAP2, enhancing BAIAP2-dependent membrane extensions and promoting filopodial protrusions.  Involved in the regulation of processes such as axonal filopodia growth, stereocilia length, dendritic cell migration and cancer cell migration and invasion.  Acts as a regulator of axonal filopodia formation in neurons: in the absence of neurotrophic factors, negatively regulates axonal filopodia formation via actin-capping activity.  In contrast, it is phosphorylated in the presence of BDNF leading to inhibition of its actin-capping activity and stimulation of filopodia formation.  Component of a complex with WHRN and MYO15A that localizes at stereocilia tips and is required for elongation of the stereocilia actin core.  Indirectly involved in cell cycle progression; its degradation following ubiquitination being required during G2 phase to promote cell shape changes (By similarity).
What are the official names of this protein?
Epidermal growth factor receptor kinase substrate 8.
What is the protein family that this protein belongs to?
Belongs to the EPS8 family.
What are the subcellular locations of this protein?
Synapse, synaptosome. Cytoplasm, cell cortex. Cell projection, ruffle membrane. Cell projection, stereocilium. Cell projection, growth cone. Note=Localizes at the tips of the stereocilia of the inner and outer hair cells (By similarity).Localizes to the midzone of dividing cells.
Protein: YCX2_TRICV
Sequence: MEKIKKSYLLVAKLKFKYFCLKPYSLNSTTKFILKIIKNKSMLIFN
What are the official names of this protein?
Uncharacterized 5.5 kDa protein in ccsA-rps6 intergenic region, ORF46.
What are the subcellular locations of this protein?
Plastid, chloroplast.