PharMolix/UniProtQA huggingface dataset:
Protein: RL332_MYCPN
Sequence: MRKKIIFVCQDCLSRNYVMSWSKQVLNRLIINKYCKHCNQKTKHLDSF
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: BASP1_BOVIN
Sequence: MGGKLSKKKKGYNVNDEKAKDKDKKAEGAGTEEEGTPKENEAQAAAETPEVKEGKEEKPEKDAQDTTKPEDKEGEKDAEAAKEDAPKAEPEPTEGAEGKPEPPKDAEQEPAAASGPSTGGDAPKASEAEAAEPAAPTKDDKSKEGGDATKTEAPAAPAAQETKSDGAPASDSKPSSTEAAPSSKETPAATEAPSSTPKAQAPAAPADEVKPAETPAANSDQTVAVKE
What are the official names of this protein?
Brain acid soluble protein 1, 22 kDa neuronal tissue-enriched acidic protein, Neuronal axonal membrane protein NAP-22.
What is the protein family that this protein belongs to?
Belongs to the BASP1 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Cell projection, growth cone. Note=Associated with the membranes of growth cones that form the tips of elongating axons.
Protein: DER_TREPS
Sequence: MKGQDVILCDGGRHFSYKVLPRVVIVGRPNVGKSTLFNRLLGRRRSITSNTSGVTRDSIEETVILRGFPLRLVDTSGFTVFSEKKASRQHIDTLVLEQTYKSIQCADKILLVLDGTCESAEDEEVIQYLRPYWGKLIAAVNKTEGGEEVHYNYARYGFSTLICVSAEHGRNIDALERAIIQNLFSVDERRELPKDDVVRLAIVGKPNTGKSTLMNYLMRRTVSLVCDRAGTTRDVVTGHVEFKQYKFIIADTAGIRKRQKVYESIEYYSVIRAISILNAVDIVLYIVDARDGFSEQDKKIVSQISKRNLGVIFLLNKWDLLEGSTSLIAKKKRDVRTAFGKMNFVPVVPVSAKTGHGISDALHCVCKIFAQLNTKVETSALNTALKDWVTSYPPPRKYGHVSLKYLVQVSVRPIEFLLFANRPDRIPENYVRFLQNRIREDLGLDSIPVKLTIRKNCRKR
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: SYE1_BART1
Sequence: MSVITRFAPSPTGFLHIGGARTALFNWLYAKHTGGKMLLRIEDTDRERSTEAAVRAIIDGLHWMGLSYDGSPISQFERAERHRQIAEQLVENGKAYYCYASPEELAEMREKARAEGRPPRYDGRWRNRDHSEAPQGIKPVIRIKAPEDGETIVHDRVQGDVRFPNKDLDDFIILRSDGSPTYMHAVVVDDHDMGVTHIIRGDDHLTNAARQTIIFKAMGWDIPVMAHIPLIHGENGAKLSKRHGALGVDAYRTMGYLPAALRNYLVRLGWSHGDDELMSLQDMISWFDIEDINKGAARFDLKKLDSINGHYMRMSNDQELFDAALDILPETDGGTEIIERLDEQRRVQFLKAIPHLKERSKTLCELIDNASFIFTQRPLQLNEKAQMLLDKNGRTILNDLYLALKACPSWDTKALDETLRSYIQTQNLKFGSIAQPLRAALTGCTTSPGVLDVLILLGRDESLYRINDQLITTVGL
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GNAT3_RAT
Sequence: MGSGISSESKESAKRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGYSKQECMEFKAVVYSNTLQSILAIVKAMTTLGIDYVNPRSREDQQLLLSMANTLEDGDMTPQLAEIIKRLWGDPGIQACFERASEYQLNDSAAYYLNDLDRLTAPGYVPNEQDVLHSRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMHESLHLFNSICNHKYFATTSIVLFLNKKDLFQEKVTKVHLSICFPEYTGPNTFEDAGNYIKNQFLDLNLKKEDKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF
What is the function of this protein?
Guanine nucleotide-binding protein (G protein) alpha subunit playing a prominent role in bitter and sweet taste transduction as well as in umami (monosodium glutamate, monopotassium glutamate, and inosine monophosphate) taste transduction.  Transduction by this alpha subunit involves coupling of specific cell-surface receptors with a cGMP-phosphodiesterase; Activation of phosphodiesterase lowers intracellular levels of cAMP and cGMP which may open a cyclic nucleotide-suppressible cation channel leading to influx of calcium, ultimately leading to release of neurotransmitter.  Indeed, denatonium and strychnine induce transient reduction in cAMP and cGMP in taste tissue, whereas this decrease is inhibited by GNAT3 antibody.  Gustducin heterotrimer transduces response to bitter and sweet compounds via regulation of phosphodiesterase for alpha subunit, as well as via activation of phospholipase C for beta and gamma subunits, with ultimate increase inositol trisphosphate and increase of intracellular Calcium.  GNAT3 can functionally couple to taste receptors to transmit intracellular signal: receptor heterodimer TAS1R2/TAS1R3 senses sweetness and TAS1R1/TAS1R3 transduces umami taste, whereas the T2R family GPCRs act as bitter sensors.  Functions also as lumenal sugar sensors in the gut to control the expression of the Na+-glucose transporter SGLT1 in response to dietaty sugar, as well as the secretion of Glucagon-like peptide-1, GLP-1 and glucose-dependent insulinotropic polypeptide, GIP.  Thus, may modulate the gut capacity to absorb sugars, with implications for the prevention and treatment of malabsorption syndromes and diet-related disorders including diabetes and obesity.
What are the official names of this protein?
Guanine nucleotide-binding protein G(t) subunit alpha-3, Gustducin alpha-3 chain.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(i/o/t/z) subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with microvilli, the presumed sites of sensory transduction in taste cells.
Protein: YL271_MIMIV
Sequence: MDIIHHFHNGQTIFDIMMTRIINNRNFQRMIDLEAPHTKQCYFTILNEQETISNVPVGTGLCVFTYHPQNRISFDELNRIFKYTNDGVYLRQVFLPTHIPRHYKCRINDQQYTNMVILGKRYDLRKSETYIELIQLGLDVISDVNVIYWTSKQNYIDATKYLISIGANIKTAIYSASKFGNLDLIISIIDGKNKDIILTAVKCMIADYHLDLAKEMISIYSELLGTEVVELTTYLESNSKLVKSTKSTKSSGSPKSIKPKKSNQNNNAKINVSQNDNSTICFDKKVQQNEITVDKMSSAKEQALNVYKEIENMENFILNKINITKKKALDKIKEIENIENTVVEKLEDKITKSNVSITNTDTITQAIISENLNSLDLLIRQGYDINKILYLACINNKKNVIDYLIDNKGANYEQVHKQLLDSKHHYKNDSTVKYLAKIIMTKSQFENVTDTDEIQQVSKKHYFKEPIHIPLGLGKDDDLSPIMVACRASKNDDQLDLVKMLVSYGFNINSRDKIGRSALHYAVNGSNRKIIEYLLALGADYSFRDNNGDTPMMLAKKSNNLELLDLFQSVPKDTKTIEPKKVTNTTDKTNLNQDIKTAMSICLSSINDNQFESVQKLIMSGFNVSSKDDTKKTLLHMAVVNNNLRIVELLINSGININSQDNLGKTPLMLACQYSHRDSKLAIVEFLLNNNAKILIKAKNNMTAIDLMSKTYNNNIYNLLCERLSINH
What are the official names of this protein?
Putative ankyrin repeat protein L271.
Protein: YQJD_ECOLI
Sequence: MSKEHTTEHLRAELKSLSDTLEEVLSSSGEKSKEELSKIRSKAEQALKQSRYRLGETGDAIAKQTRVAAARADEYVRENPWTGVGIGAAIGVVLGVLLSRR
What is the function of this protein?
Upon overexpression inhibits growth.
What are the official names of this protein?
Uncharacterized protein YqjD.
What is the protein family that this protein belongs to?
Belongs to the ElaB/YgaM/YqjD family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein. Note=Predominantly localized to 1 cell pole in stationary phase, with a few smaller foci elsewhere in the cell; polar localization depends on the minCDE operon.
Protein: HEMH_RICCK
Sequence: MKKRIAIVLFNLGGPNSLELVKPFLFNLFYDKAIINLPNPLRYIIAKIISIIRERKSQKIYSLIGGKSSLLQETQEQRLLLTKKLKQLIKEDFAVFINMRYSAPFVKETINQIKKYNPSEIILLPLYPQFSSTTTGSSVKNFLQNLDIPIKTLDIPIKTVCCYPLEEDFIKAHVSLIKEKLYDKNFCILFSAHGLPEKIIKAGDPYSFQIKETVKAIVKELNIKDLDYKITYQSRVGPIEWLKPNTEDEIELAGKLKKDVIIVPISFVSEHVETLVELDIEYKLIADKYEIQYTRIPTLGTNKIFINSLTNILLRFINKVDTNLVTSSSSTRICPNEFTKCLCKLKN
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM235_MOUSE
Sequence: MALLATLLLSAALGALLSFALLAAAVASDYWYILEVADAGGLGGVQLFSHSGLWRTCEGQNSCVPLIDPFASAGLEVSPSVQHLLSLHRTVMVVLPLSLVLIVCGWVCGLLSSLSQSVPLLLATGCYFLLGGALTLAGLSIYISYSHLAFVEAARTYGVTHVQNVHISFGWSLALAWASCASEVLSGALLLAAARLLSLSQRPGVPHSVIL
What are the official names of this protein?
Transmembrane protein 235, Claudin-27.
What is the protein family that this protein belongs to?
Belongs to the PMP-22/EMP/MP20 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Endoplasmic reticulum.
Protein: KCY_PSEFS
Sequence: MNIKAPVITIDGPSGSGKGTIAGILAKRLGWCLLDSGALYRLLAFAARNHGVDLTNEESLKLLAAHLDVQFVGATEGHPQRIILEGDDVTDDLRNEQVGSWASQVAALPAVRDALLQRQRAFQEPPGLVADGRDMGTVVFPEAPLKIFLTASAEERARRRYLQLKGKVDGVSLSSLLDEIRARDERDTQRAVAPLKPAADAIQLDSTELSIEQVLERIMSEIAIRDIAG
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_DEHMB
Sequence: MIIAVDVDGGDYAPKEIIKGALKAAQEYKIGLILLGKKEVIHVHAGHYLKKLPIEIVHCPQTVTFNEHAVEAIKGKPQSAIVIGTSLVKQGKADAFISAGNTGAVLAAAFFILGKIDGVERPALGAIITTRPHIPSLLIDAGANAECRPNHLDEFAHLGNIYAKQVLGLENPRIGLLNNGEEEAKGTKLTLETHQLLKKSKLNFIGNIEGHDISLNKADVIVTDGFTGNIVLKTLEGLGDALLKVRKVGHAIDSAAHLRGRALLADVGLGSMVKGMDFEECGGACLLGVKGTIIVAHGRSHARAIKNAIGLAKRTAEKGVDKLIAEDIKSRTKAGTEGDPKNVNTPV
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: F174B_BOVIN
Sequence: MRAALPPARLLPLLLLLALLGAPAARASRAQSAAPPQPGAERQPRPPPGPGPGNATGTGSGEAAGGGGSSNSSGDALVTRISSLLRDLHTLKAAVIVACAFTAFLIACLLLRVFRSGKRLKKTRKYDIITTPAERVEMAPLNEEDDEDEDSTVFDIKYR
What is the function of this protein?
Essential for Golgi structural integrity.
What are the official names of this protein?
Membrane protein FAM174B.
What is the protein family that this protein belongs to?
Belongs to the FAM174 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Golgi apparatus.
Protein: PSD_ACIBT
Sequence: MSFTSRLKKELFIKAQNLVPQHQLSRVVGKVAASENPILKAAVIHAFKTKYGIDLSIAEQGNALKYKSFNDFFTRALKDGVRLVDENPDSIVSPADGAISQIGKITAGEVFQAKGQSFSVEKLIGDPQLAQPFQEGEFATVYLSPRDYHRVHMPFSGTLTETLYVPGELFSVNQVTAENVPGLFARNERMVCLFDTELGRMAVVLVGAMIVAGIETVATGKVKPSGRIELQHHELKLEKGAELGRFYLGSTAIILFEKDKIEWEKRYKAESVVVMGERMGHTL
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RPOA_LIMRJ
Sequence: MIEFEKPNIHKVEETDNYGKFVVEPLERGYGTTLGNSLRRVLIASLPGAAITSMQIDGVLHEFSTVEGVTEDVTQIILNLKKVSLKLDSEDQKNLELDVKGPAEVTASDIQGDNEVTILNPDLHIATVADGAELHIKLTADKGRGYLSANDNKARMDDLAIGVLPIDSIYTPIERVNYTVENARVGQRNDYDKLTLDVWTDGSLTPTEAVSLGAKILTEHLAMFVDLTETAQNAQVMVEKEETHKEKMLEMTIEELDLSVRSYNCLKRAGINTVKELTDRTVSDMMKVRNLGQKSLEEIKLKLNDLGVSFRQDD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: GLPG_YERPE
Sequence: MTRVIVISNLRLAQAFVDYMATHHVALEIRPDAQGVEIWLADDEQLSAVQHELEQFLLDPLNPRYQAASWQAGNVNSNLPYQRFSYLQTLRSQAGPLTLSVMVLCIAIYILMLITGDMAVMSWLAWPYNSSQYLQIWRWVSHAFLHFSLLHILFNLMWWWYLGGQMEKRLGTSKLLVLTIVSAVFSGWGQSLFSGANFGGLSGVVYALMGYVWLTGERAPERGISLPRGLMAFSVLWLIAGYFDILGLSIANAAHVSGLIIGLLMAFWDTRNSARTVQ
What is the function of this protein?
Rhomboid-type serine protease that catalyzes intramembrane proteolysis.
What are the official names of this protein?
Rhomboid protease GlpG, Intramembrane serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RBL_PELRO
Sequence: GVGFKAGVKDYRLTYYTPEYKTKDTDILAAFRMTPQPGVPAEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYDIEPVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALXXEDLRIPPAYSKTFMGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFVAEALFKSQAETGEVKGHYLNATAGTCEEMMKRAIFARELGAPIVMHDYLTGGFTANTSLAFYCRDNGLLLHIHRAMHAVIDRQKDHGMHFRVLAKGLRMSGGDHIHAGTVVGKLEGEREVTLGFVDLLRDDFIQKDRSRGIYFTQDWVSMPGVFPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREASK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SAL_PIG
Sequence: MKLLLLLCLGLTLASSHKEAGQDVVTSNFDASKIAGEWYSILLASDAKENIEENGSMRVFVEHIRVLDNSSLAFKFQRKVNGECTDFYAVCDKVGDGVYTVAYYGENKFRLLEVNYSDYVILHLVNVNGDKTFQLMEFYGRKPDVEPKLKDKFVEICQQYGIIKENIIDLTKIDRCFQLRGSGGVQESSAE
What is the function of this protein?
Binds pheromones, the pheromones are released from the saliva of males and affect the sexual behavior of females.
What are the official names of this protein?
Salivary lipocalin, SAL.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: BIOB_CHLL2
Sequence: MTSSVIHQAVIDAYRVLDTGEPLDRETALRLAALPGDAVLDLASLAHKVRLRYAGEAASLHACSIMNAKSGECGENCRFCAQSRHNSASIDVYDLAGEDAVLRQAEEAVDSGIPHFGIVTSGYGYLKITPEFNRILGMIDMLHRELPGLNVCASLGVLGEETSAALAAHGIAHYNINIQVAPSRYSDLIADTHTVVERIATVRLLRKHRIPVCCGGILGVGESMTERLEMIFALSELDVSVIPLNVLVPIDGTPLEGHRTADIADIVKTFAICRLVHPRTIIKFAAGRETVMKDFQGLLMLSGANGFLTGGYLTTRGREIDADRELGRQLESFTEG
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: ODPA_STAAS
Sequence: MAPKLQAQFDAVKVLNDTQSKFEMVQILDENGNVVNEDLVPDLTDEQLVELMERMVWTRILDQRSISLNRQGRLGFYAPTAGQEASQLASQYALEKEDYILPGYRDVPQIIWHGLPLTEAFLFSRGHFKGNQFPEGVNALSPQIIIGAQYIQAAGVAFALKKRGKNAVAITYTGDGGSSQGDFYEGINFAAAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDALAVYQATKEARDRAVAGEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWEKKDPLVRFRKFLENKGLWNEDKENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYEDMPQNLAEQYEIYKEKESK
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit alpha.
Protein: PPK1_SYNY3
Sequence: MIQAMPSAPTVDFKDPAYYFNRELSWLAFNQRVLHEGLDDRTPLLERLKFLAIFCSNLDEFFMVRVAGLKQQVEANVTKLTADGRTPSQQLKEISKSLRPLVYQQNQVFEYVLKEKLADEGIFLNDYVDLSQEERQYLHQFYDDHIFPVLTPLAVDPSHPFPYISNLSLNLGVVVRDPDTDEELFARVKVPPTLPRFVALPEDVCQPDPNKPWLWTGVPLEQVIAHNLASLFPGMIIQECHLFRVTRNADIAVEEDEADDLLLAIEEELRKRRVGKSAVRLEINASTPKNIRDRLMTDLGLEEIDVYDIDGLLGLKDLFFFLSLPAPHLKDEPWASVIPPRLKHVYEFVDGDEDGRVQQEGIDIFTLIRQGDILVHHPYQSFTASVQQFITQAAYDPHVLTIKMTLYRTSGDSPIVNALIAAAENGKQVAVLVELKARFDEENNINWARKLEQYGVHVVYGLVGLKTHTKTVLVVRQEGPDIRRYVHIGTGNYNPKTAKLYTDLGLITCRPELGNDLTNLFNFLTGYSRQKDYQKLLVAPVNMRERMVAMIEREADHCLNGGTGRIVAKMNSLVDTQIIRALYAASQAGVQIDLIVRGICCLRPGVENVSENIRVISVIGRLLEHSRIFYFHNGGEEEIYIGSADWMSRNLTRRVEAVVPVEQPDLKQELQSILGILLADNRQAWELQPDGTYVQRRPASPEQSQSSQAIFTAQAIAETTEDPELRSV
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
What are the official names of this protein?
Polyphosphate kinase, ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 1 (PPK1) family.
Protein: INS1B_CONTU
Sequence: MTTSFYFLLMALGLLLYVCQSSFGNQHTRNSDTPKYRCGSDIPNSYMDLCFRKRNDAGKKRGQASPLWQRGGSLSMLKARAKRNEAFHLQRAHRGVVEHCCYRPCSNAEFKKFCG
What is the function of this protein?
This venom insulin, from a fish-hunting cone snail, facilitates prey capture by rapidly inducing hypoglycemic shock (By similarity).  It is one of the smallest known insulin found in nature and lacks the C-terminal segment of the B chain that, in human insulin, mediates engagement of the insulin receptor (INSR) and assembly of the hormone's hexameric storage form (By similarity).  Despite lacking this segment, it both binds and activates human insulin receptor (long isoform (HIR-B) of INSR) with a high potency (EC(50)=12. 0 nM) (PubMed:30747102).  In vivo, intraperitoneal injection of this peptide into zebrafish lowers blood glucose with a lower potency than human insulin (By similarity).  In addition, when applied to water, this peptide reduces overall locomotor activity of zebrafish larvae, observed as a significant decrease in the percentage of time spent swimming and movement frequency (By similarity).  When tested on a mouse model of diabetes, this insulin also lowers blood glucose with a 10-fold lower potency than human insulin (By similarity).
What are the official names of this protein?
Con-Ins T1B, Con-Ins T2, Insulin 2.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PANC_TRIL1
Sequence: MKLIHDVQEMQQTVLGLKRQGKRIAFVPTMGFLHEGHASLMREGRTRGDVLVLSIFVNPTQFGINEDLASYPRNLEGDCALAESCGVDLVFAPTAAGMYPPGFQTTVALGPLTKPLCGASRPGHFDGVAVVVTKLFGIVQPDCALFGKKDFQQLAIIRQMTLDLNLPVEIIGMPIVREPDGLAMSSRNSYLSVEQRQQALCLHRAILKVRELFKGGETSVDRLLGEARMIITAVPEASVDYLELRDSTTLEPVATAAADSLFALAVKIGSTRLIDNTVLGDTP
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATC_CARHZ
Sequence: MEDKPMTLFEHLEALRKVIIISVIAIVIGSIIAYNYVDYFLNILLQPVTALKMKLVFINVTEAFMTKLKIAIILGIILASPIILWQIWSFVAPGLKPAERKFILRMIPVIIILFVAGIVFAFFTVFQIATRFLLQFGGDIMSPMITIGKYISFALNFLIPFGLVFELPVVVYILAKLNIISHEFLVKNRKYALLVVFILAAALTPGPDVISQLLMAAPLLILYEVSIFIAKFIKPKEFSGERK
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.
What are the official names of this protein?
Sec-independent protein translocase protein TatC.
What is the protein family that this protein belongs to?
Belongs to the TatC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DAPAT_METST
Sequence: MAVKVNEYYSLIQNNYLFVEIARRVDEYQKENPDANLIKMGIGDVTRPLAKSVVEAFKRAVDELGDADTFRGYGPEQGYDFLIEDVIENDYKPLGVELKNSEVFISDGAKCDTGNFQELFSKDNIIAVTDPVYPVYVDSNVMAGRSGKMGEDGFYENIVYLPATSENDFVPSLPSEKVDIIYLCYPNNPTGTTLTKEQLKEWVDYAHENDALILFDAAYESFIKTPGIPHSIFEIEGAKDVAVEFRSYSKVAGFTGTRCAYCVVPEEVYVKDANGNKVQLNPLWNRRQSTKFNGVSYPVQRAAQAIYTPEGKKEIQENLDYYVKNAQVIRESLEKMGLKVYGGVDSPYIWFKTPNDIDSWSFFDILLKEAHVVSTPGAGFGPSGEGYLRLTAFNTYENTVEAMDRISKLEF
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: DAPA_METM6
Sequence: MQGVYPAIVTPFKDGKVDYDGLRTNIDYLIENGVSGVIPVGTTGESPTLTPLEHEKVIEKVVEFVDGRVEVIAGTGSNSTSEALEFSQYAEDVGVDGVLLITPYYNKPSQEGLKRHFGEIANSINVPIVLYNVPSRTALNIEPETIKYLFEEYSNITAIKEANPNLSQVSEVLDSCNIDVLSGNDELTLPIISLGGKGVVSVVANIAPKEFVQMVDFANAGKFDKAKEIHYKLFPLMKLMFIETNPIPIKTAMNMLGMPSGELRLPLCEMAESNKLKLQNALNNLGLLK
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MECA_OCEIH
Sequence: MRIERVSTDQFKIFLTFDDLIERGFTREDLWHDASNVRSLFSDMMYEASSELGIELEGMLLVQVHLMQAQGMHIFVTQQYEDNSEDEDYIEMKVTLDESKELIFSFMDFEDIISVTSYLDPMGLENIRLYYMEDRYYMILDHIELSRVDKEDIIGVMSEYANPSIVTSHRIEEYGKLIMEENTVQQIKRFFY
What is the function of this protein?
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.  Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease.  When overexpressed, inhibits sporulation.  Also involved in Spx degradation by ClpC.
What are the official names of this protein?
Adapter protein MecA.
What is the protein family that this protein belongs to?
Belongs to the MecA family.
Protein: LGB2_PHAVU
Sequence: MGAFTEKQEALVNSSWEAFKGNIPQYSVVFYTSILEKAPAAKNLFSFLANGVDPTNPKLTAHAESLFGLVRDSAAQLRANGAVVADAALGSIHSQKALNDSQFLVVKEALLKTLKEAVGDKWTDELSTALELAYDEFAAGIKKAYA
What is the function of this protein?
Provides oxygen to the bacteroids.  This role is essential for symbiotic nitrogen fixation.
What are the official names of this protein?
Leghemoglobin.
What is the protein family that this protein belongs to?
Belongs to the plant globin family.
Protein: SCX6_CENLI
Sequence: MNSLLMIIGCLVLIGTVWTKEGYLVNMKTGCKYGCYELGDNGYCDRKCKAESGNYGYCYTVGCWCEGLPNSKPTWPLPGKSCSGK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Toxin Cll6.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.