PharMolix/UniProtQA huggingface dataset:
Protein: SGF11_YEAS7
Sequence: MTEETITIDSISNGILNNLLTTLIQDIVARETTQQQLLKTRYPDLRSYYFDPNGSLDINGLQKQQESSQYIHCENCGRDVSANRLAAHLQRCLSRGARR
What is the function of this protein?
Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA.  At the promoters, SAGA is required for recruitment of the basal transcription machinery.  It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination.  SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac).  SAGA interacts with DNA via upstream activating sequences (UASs).  Involved in transcriptional regulation of a subset of SAGA-regulated genes.  Within the SAGA complex, participates in a subcomplex, that specifically deubiquitinates histones H2B.
What are the official names of this protein?
SAGA-associated factor 11.
What is the protein family that this protein belongs to?
Belongs to the SGF11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TACT_RAT
Sequence: MGRKWTYCVVYAIIQIQFFRGAWEELFNAGDNNVYALPGSDVNLTCQTMEKDLMVQMQWSKVTDEIDMIVVYHPQYGFHYMQGVACESRVAAVETLKDATKWTLNLRNISSSLSGKYECSFTMYPTGTKTIVYNLIVEPYTQDEHNRTIEIETNRTLEIPCFQNTSSEISPRFTFSWLVEKDGVEDVLFTYDYHVSNSTAFKGRVGLGADYGLRLSPVQIQDDGRTFSCFLRISPLKVWKTSTTVKVFAKPEILMTVENTTMDVLGERVFTCLLKNVFPKASITWLIDGRLFQGNEEGIYITNEEKNSSSGFWELKSVLTRMHNRTSQSNNMTVWCMALSPGPGNKMWNTSSQPITFSLDSGTAPTKRLPNVTGSTLGAQTFPDAEVSPTRYLATSSMTIVDENVLTPDPTPQTSNSSMTTKDVNYSQPSSGTDAKNSSRAASSSDGGSRPFPSTSPPKWLSLPHTSTGPQEPDSAVSWIPTDAYTSGSSDASLTSHDVIIRTTKEFPDVLTTANGTTKIKHGHVTGITVNKPRDGMSWPVAVATLLFFCILLFGLGVRKWCQYQKEIMERPPPFKPPPPPIKYMCIQEPTGRGMPCHEMEVL
What is the function of this protein?
May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response.  Promotes NK cell-target adhesion by interacting with PVR present on target cells.  May function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation (By similarity).
What are the official names of this protein?
T-cell surface protein tactile, Cell surface antigen CD96, T cell-activated increased late expression protein.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SSRP_ALKOO
Sequence: MASKGTKLIATNKKARHDYFIEETFETGIVLVGTEVKSIRQGKLNIKDGYARVENSEVFLYNVHISPYEQGNIFNKDPLRVRKLLLHKSEIRKLIGYVQQKGYTLIPLSFYLKDGLIKVELGIGVGKKIYDKRQDIAKKDAARRIDKELRQREKQ
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: YABP_BACSU
Sequence: MNSYYDQKGSSSVPEQHDVTMKGRKHLDISGVKHVESFDNEEFLLETVMGMLSVRGQNLQMKNLDVEKGIVSIKGRVFDLVYLDEQQGDKAKGFFSKLFK
What is the function of this protein?
Required for sporulation.
What are the official names of this protein?
Spore protein YabP.
What are the subcellular locations of this protein?
Forespore outer membrane. Note=Forms a ring around the forespore.
Protein: UREG_KLEAE
Sequence: MNSYKHPLRVGVGGPVGSGKTALLEALCKAMRDTWQLAVVTNDIYTKEDQRILTEAGALAPERIVGVETGGCPHTAIREDASMNLAAVEALSEKFGNLDLIFVESGGDNLSATFSPELADLTIYVIDVAEGEKIPRKGGPGITKSDFLVINKTDLAPYVGASLEVMASDTQRMRGDRPWTFTNLKQGDGLSTIIAFLEDKGMLGK
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMCAL_LISIN
Sequence: MKATGIVVEYNPFHNGHQLHLNKARELTKSDVVIAVMSGSFVQRGEPAIIPKWERTKMALAAGVDMVIELPVSFATQHATIFAEESIRLLDALHIDTLFFGSEHGVSEDFSTAAKTVVENEAAFNETIQLALGDKKTSYARAYTDAFTHLFGKELLDVTKPNNILGFHYALAIQKQNPSIALQTMPREHSGYHDAEASHDYIASATAIRKLLLAGNLEEASRYLPDSSIEVLNNYRGPFLSFEDYWPLLKFRLIQASSDELEGIRGVSEGIQNRMQLAAKKAHSFSDFIEIMKTKRYSNARLQRTALQILLNAQNTPPAEPYIRVLGMSKTGQKYLSLHKKNISLPIVTTVSKAEPSLLKEDLRATDIYTLINGLEDYQAGDFHTPPILTL
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_TROWT
Sequence: MTRVILVQDVNGLGSVGDVVEVKAGYSRNYLVPKGMAVRWTEGAQKHIGDISAARRAREAAALQEARDIANTLAKEAVTRELRLAANAGEDGRLFGSVTAANIAKVLSSASGHKIDRGKIEIDSPIKTLGEHTVKVKLHPNVKVDINVVVYAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: YBJC_ECOLI
Sequence: MRAIGKLPKGVLILEFIGMMLLAVALLSVSDSLSLPEPFSRPEVQILMIFLGVLLMLPAAVVVILQVAKRLAPQLMNRPPQYSRSEREKDNDANH
What are the official names of this protein?
Uncharacterized protein YbjC.
Protein: EIF3H_DICDI
Sequence: MDIDEQIIQDYSNSKLDVVQIDGLVVLKIIKQCKEYLPELVPGQLLGLDIGTSLEVSNCFPFPPRDQEDENSESIADYQLEMMRFLREVNIDSNTVGWYTPTYLNSFFNESVIETQYNYQATINQKCVVIVYDPIKTSQGTLSLKCYRLTQSFMELFKDQSFSRERLDQANLSFNDIFEQIPIKIHNSQLINALLYEFDGASNNLTNSFDRLNISNNIYLEKVVEGMTDCLESLNQELNKVYINQRNIQTQKTNYIQQKFLEGQKVDEDELASMIKPLNPPSKLTSLLLTNQINNYTDQIHSFSGNSLTKLSLLKDLQK
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit H, eIF3h, Eukaryotic translation initiation factor 3 subunit 3, eIF-3-gamma.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_METEP
Sequence: MARRPGSSSRGPARSDRLPAEAVTSARKPHAAAPTPPASPDPGLVLLGEFGRPHGLHGEVRLKSHTSEPLAIAGYGPLHASDGRTLELANVRPAAGSSPDLLIVRVKGVDDRTGAEALNRVTLAIARERLGKVEDEDEFFLTDLIGLTVEDGAGTVIGTIVAVPNFGGGDLLEIRPAAGGPTALLPFTKAFVPSLDIAGGKVVADPPDDLFAPPGPKPADDPG
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADE_ECO57
Sequence: MTLQQQIIKALGAKPQINAEEEIRRSVDFLKSYLQTYPFIKSLVLGISGGQDSTLAGKLCQMAINELRQETGNESLQFIAVRLPYGVQADEQDCQDAIAFIQPDRVLTVNIKGAVLASEQALREACIELSDFVRGNEKARERMKAQYSIAGMTSGVVVGTDHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLAALGCPEHLYKKAPTADLEDDRPSLPDEVALGVTYDNIDDYLEGKNVPQQVARTIENWYLKTEHKRRPPITVFDDFWKK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: Y1072_EDWI9
Sequence: MPSFDIVSEVDLQEVRNAVENATRELASRWDFRNVEASVELNEKNETIKLTTISDFQVKQLVDILREKLVKRGIEAGALEIPEECEHSGKLYSVEAKLQKGIDSVMAKKLVKLIKDSKLKVQTQIQGEQLRVTGKSRDDLQGAMALVRGADLGQPFQFNNFRD
What are the official names of this protein?
UPF0234 protein NT01EI_1072.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: RUVA_MICLC
Sequence: MIASLSGTVEHVALDRAVIAVGGLGVQFSATPQTLSTLHEGRPGAVQTHLVVKEDALTLYGFADRDEREVFEVLITANGVGPRLALAILSVHHPETVRRAVTEEDEKTLTRVPGIGPKMARKIIVELSGRLAPTGEPVPGAEAEASDEPAVETVWHADVVQAMAGLGWSEKEALKAVEATVAARPELDEGRDVAALLRATLRDVGMAGAVRGGR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: TPIS_GLOC7
Sequence: MRKIIIAGNWKMYKTQAEALEFVQVFKSKIEDTDESREIVLCAPFTDLGAMSKNLHGSRIKLGAQNVHWEEAGAYTGEISGAMLTEIGVSYVIVGHSERRQYFGDTDETVNLRVLAAQKYGLIPILCVGESKSQRDAGETEKIIINQLKRDLVDVDQNKLVIAYEPIWAIGTGDTCESSEANRVIGIIREQLTNKNVSIQYGGSVKPGNIDEIMKQSEIDGALVGGASLNPADFAQIVNYK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURQ_SALPA
Sequence: MNLGTLVSETRNPQTMDLDALPTPELVKRFNEQDTLVAEAVKATLPDVARAVDAAAAALKSGGRIIYMGAGTSGRLGVLDASECPPTFGVPHGLVVGLIAGGPGALLKAVEGAEDSQQAGEDDLVALNLQEQDLVVGLAASGRTPYVIGGLRYARQSGCTTVAVSCNPDSPIAREANIAISPVVGPEALTGSTRLKSGTAQKMVLNMISTGAMVKFGKVYQNLMVDMKATNVKLVDRACRMVVEATGIGREEAEALLKQTDFEVKPAILMALTGLDAAAAREKLAAHQGFLRAALEH
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: RSMA_STRT2
Sequence: MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEINKNVNVIEIGPGIGALTEFLAENASEVMAFEIDERLVPILEDTLRDHDNVKVINEDVLKADLQTRVKEFENPDLPIKVVANLPYYITTPILMHLIESKIPFSEFVVMMQKEVADRISAEPNTKAYGSLSIAVQYYMTTKMAFAVPRTVFVPAPNVDSAILKMTRRKQPLVEVKDEDFFFRVSKASFLHRRKTLWNNLTSHFGKSEEVKNKLDQALENAAIKPSIRGEALSISDFARLSDALREAGL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OR1L6_HUMAN
Sequence: MSYFYRLKLMKEAVLVKLPFTSLPLLLQTLSRKSRDMEIKNYSSSTSGFILLGLSSNPQLQKPLFAIFLIMYLLAAVGNVLIIPAIYSDPRLHTPMYFFLSNLSFMDICFTTVIVPKMLVNFLSETKVISYVGCLAQMYFFMAFGNTDSYLLASMAIDRLVAICNPLHYDVVMKPRHCLLMLLGSCSISHLHSLFRVLLMSRLSFCASHIIKHFFCDTQPVLKLSCSDTSSSQMVVMTETLAVIVTPFLCIIFSYLRIMVTVLRIPSAAGKWKAFSTCGSHLTAVALFYGSIIYVYFRPLSMYSVVRDRVATVMYTVVTPMLNPFIYSLRNKDMKRGLKKLQDRIYR
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 1L6, Olfactory receptor 1L7, Olfactory receptor OR9-30.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TILS_STRT2
Sequence: MTEKLLQMMQEKGYFNQHKKVLVAVSGGADSMSLLHFLYNHQKDLDIQLGIAHVNHKQRQESEYEENYLRHWAKEHKVPFHYSAFSGKFSENAARTFRYDFFKRIMKEADYSALVTAHHADDQAETIFMRLLRGSRLRHLSGICDVRSFGTGQIIRPFLHIPKDQLPVTFHFEDRSNSSLAYLRNRIRLTYLPTLSQENPKFKEHLCLLADEIALMDKALEELTKDITITDLSVFQQQTDAVQHLLIQSYLESFPDLQLSKGQFNQLMSFLRKKTSGKMPLKNGYVLVKTQTDFLITKEEPISLSSPSLLEFGKSIVFEEYLLTFSEPHVVSNVDTINIWSDAPIVIRHRHEGDRIDLGTHHKKIRRLFIDNKISEKDRQKAIIGEQDGQIIFLYVAGRLYLKKRPKNAILYGTVVIYKKF
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_BACCN
Sequence: MIEIEKPKIETVELNEDAKYGKFVIEPLERGYGTTLGNSLRRILLSSLPGAAVTAIQIDGVLHEFSTVEGVVEDVTTIILNLKKLALKIYSDEEKTLEIDVQGEGIVTAADITHDSDVEILNPDLYIATLAKDAHFRVRLTAKRGRGYTPADANKSEDQPIGVIPIDSIYTPVSRVTYQVEKTRVGQVANYDKLTLDVWTDGSIGPKEAISLGAKILTEHLNIFVGLTDEAQNAEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVQELANKTEEDMMKVRNLGRKSLEEVKHKLEELGLGLRKDD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: MCAL_CERS4
Sequence: MSFRLQPAPPARPNRCQLFGPGSRPALFEKMAASAADVINLDLEDSVAPDDKAQARANIIEAINGLDWGRKYLSVRINGLDTPFWYRDVVDLLEQAGDRLDQIMIPKVGCAADVYAVDALVTAIERAKGRTKPLSFEVIIESAAGIAHVEEIAASSPRLQAMSLGAADFAASMGMQTTGIGGTQENYYMLHDGQKHWSDPWHWAQAAIVAACRTHGILPVDGPFGDFSDDEGFRAQARRSATLGMVGKWAIHPKQVALANEVFTPSETAVTEAREILAAMDAAKARGEGATVYKGRLVDIASIKQAEVIVRQAEMISA
What is the function of this protein?
Involved in the ethylmalonyl-CoA pathway for acetate assimilation.  Catalyzes the reversible condensation of glyoxylate and acetyl-CoA to L-malyl-CoA and the reversible condensation of glyoxylate and propionyl-CoA to yield beta-methylmalyl-CoA.  It is also able to catalyze the cleavage of (S)-citramalyl-CoA to yield acetyl-CoA and pyruvate, although this reaction is not involved in the ethylmalonyl-CoA pathway.
What are the official names of this protein?
L-malyl-CoA/beta-methylmalyl-CoA lyase, (3S)-malyl-CoA/beta-methylmalyl-CoA lyase, (S)-citramalyl-CoA lyase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family.
Protein: G3PC_CRAPL
Sequence: MAKVKIGINGFGRIGRLVARVALVRDDVELVAVNDPFITVDYMAYMFKYDTVHGQYKHHELKVKDEKTLLFGDKPVAVFGLRNPEEIPWAETGAEYVVESTGVFTEKEKAAAHLKGGAKKVIISAPSKDAPMFVVGVNEKTYTPDIDVVSNASCTTNCLAPLAKVIHDRFGIVEGLMTTVHSITATQKTVDGPSSKDWRGGRAASFNIIPSSTGAAKAVGKVLPDLNGKLTGMAFRVPTVDVSVVDLTVTLAKEASYDEIKAAIKEESEGKLKGILGYTEEDVVSSDFVGDSRSSIFDAKAGIALSKKFVKIVAWYDNEWGYSSRVVDLIRHMAAAK
What is the function of this protein?
Key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate.  Essential for the maintenance of cellular ATP levels and carbohydrate metabolism (By similarity).
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, cytosolic.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HAM2_CAEEL
Sequence: MPYRAELKRPDLKGSFPCSICQKVFCHSSSLSRHRMQAHFKSYTCTTCNNEIPSNDTLRSHMYRVHNITRMFMCRCCNWAFPDKTSLHIHMQSMLKNGTPGEAAVLAKSSDVVDSTSESGSPRQSPPFSPDLLMQKRMLQVAANNNNIGSIFPTLLKSPDSKSMFPLDLSNMGPSQFLSAWLANNPINTAALNLAAQQTPSKDSIQSSNISDYDDLEVQTTEEDIKFEVESSDVSPRSVIVKTEPTFKRELEHDADIDVEGDDGEPPLKMTIDDKNIHISHDQPSPTVSDSHISGGSSSHSGESLKCFDCQVARGKLVAVEDKCRAYEKTIRELQVQVDFLRKIQPNPMPPVMLPPPMMPMPSPGPNNLFQNPAMRMLLNNLIHMNRPSVVP
What is the function of this protein?
Probable transcription factor that acts downstream of egl-15, to promote migration of the HSN motor neurons from the tail to the gonad primordium during HSN cell differentiation (PubMed:10049362).
What are the official names of this protein?
Zinc finger protein ham-2, HSN abnormal migration protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: MTPN_BOVIN
Sequence: MCDKEFMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAFEATDNQAIKALLQ
What is the function of this protein?
Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity.  Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation.  Promotes cardiac muscle hypertrophy.  Plays a role in the regulation of the growth of actin filaments.  Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer (By similarity).
What are the official names of this protein?
Myotrophin.
What is the protein family that this protein belongs to?
Belongs to the myotrophin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, perinuclear region.
Protein: RL13_DEHM1
Sequence: MNTYTVKASDIKRDWHVIDASGRVLGEVAAEAAKYLMGKHKPMFCRNLDCGDYVVIINAKKVTVTGNKLDQKIYYRHSGFPGGFRQEKLGDLLKTKPLFVIEHAVKGMIPRNTLGAQILAKLKVYEGEEHPHASQTGEVSKES
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: CCSA_BUXMI
Sequence: MIFLTLEHILTHISFSIVSIVITIHLITLLVDEIVGLYDSLEKGMISTFLCITGLLVTRWIYSGHLPLSNLYESLIFLSWSFSIIHMIPYFKNHKNHLSLVTAPSAIFTQGFATSGLLTEMHQSAILVPALQSQWLMMHVSMMVLSYGALLCGSLLSVALLVITFRKNIDIFGKRNHLLIGSFSFGEIQYTNERSNVLRNVSFLSLRNYRRYQLIRQLDNWSYRVISLGFIFLTIGILSGAVWANEAWGSYWNWDPKETWAFITWTIFAIYLHTRTNKNFQGADSAIVASIGFIIIWICYFGVNLLGIGLHSYGSFILTSN
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RS15_GEOUR
Sequence: MLATDKKQEIISTYKLHDSDTGSPEVQIAILTERITYLTEHFKTHKKDHHSRRGLLKIVGQRRGLLDYLKKKDVERYRSIIEKLGIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RECC_MYCTU
Sequence: MALHLHRAERTDLLADGLGALLADPQPDPFAQELVLVAARGVERWLSQRLSLVLGCGPGRADGVCAGIAFRNPQSLIAEITGTLDDDPWSPEALAWPLLAVIDASLDEPWCRTLASHLGHFATTDAEAELRRGRRYSVARRLAGLFASYARQRPGLLAAWLDGDLGELPGDLAWQPPLWRALVTTVGADPPHVRHDKTIARLRDGPADLPARLSLFGHTRLACTDVQLLDALAVHHDLHLWLPHPSDELWRALAGFQGADGLLPRRQDTSRRAAQHPLLETLGRDVRELQRALPAARATDEFLGATTKPDTLLGWLQADIAGNAPRPAGRSLSDADRSVQVHACHGPARQIDVLREVLLGLLEDDPTLQPRDIVVMCPDIDTYAPLIVAGFGLGEVAGDCHPAHRLRVRLADRALTQTNPLLSVAAELLTIAETRATASQLLNLAQAAPVRAKFGFADDDLDTITTWVRESNIRWGFDPTHRRRYGLDTVVHNTWRFGLDRILTGVAMSEDSQAWLDTALPLDDVGSNRVELAGRLAEFVERLHHVVGGLSGARPLVAWLDALATGIDLLTACNDGWQRAQVQREFADVLARAGSRAAPLLRLPDVRALLDAQLAGRPTRANFRTGTLTVCTMVPMRSVPHRVVCLVGLDDGVFPRLSHPDGDDVLAREPMTGERDIRSEDRQLLLDAIGAATQTLVITYTGADERTGQPRPPAVPLAELLDALDQTTSAPVRERILVTHPLQPFDRKNVTPGALLGAKPFTFDPAALAAAQAAAGKRCPPTAFISGRLPAPPAADVTLADLLDFFKDPVKGFFRALDYTLPWDVDTVEDSIPVQVDALAEWTVGERMLRDMLRGLHPDDAAHSEWRRGTLPPGRLGVRRAKEIRNRARDLAAAALAHRDGHGQAHDVDVDLGDGRRLSGTVTPVFGGRTVSVTYSKLAPKHVLPAWIGLVTLAAQEPGREWSALCIGRSKTRNHIARRLFVPPPDPVAVLRELVLLYDAGRREPLPLPLKTSCAWAQARRDGQDPYPPARECWQTNRFRPGDDDAPAHVRAWGPRAPFEVLLGKPRAGEEVAGEETRLGALAARLWLPLLAAEGSV
What is the function of this protein?
A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair.  Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity.  Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction.  Cuts ssDNA a few nucleotides 3' to the Chi site.  The properties and activities of the enzyme are changed at Chi.  The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair.  Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination.  In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
What are the official names of this protein?
RecBCD enzyme subunit RecC, Exonuclease V subunit RecC, ExoV subunit RecC, Helicase/nuclease RecBCD subunit RecC.
What is the protein family that this protein belongs to?
Belongs to the RecC family.
Protein: Y415_PASMU
Sequence: MRYNSFLSVLALFNVLLWFTFILAISMTFSAINLLMSKKFTMKNVQPTRLDWFFVLLPYVIGLFFAIFDSATIGQVFFWGA
What are the official names of this protein?
Uncharacterized protein PM0415.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.