PharMolix/UniProtQA huggingface dataset:
Protein: TSAD_METS4
Sequence: MNVLGIETTCDETAAAIVTAAEDGRAVIRANEVLSQIAEHAAYGGVVPEIAARAHVEVVDRLIARALQEAGLGFDDLDGIAVAAGPGLIGGVLVGLVTAKTLSLVTRKPLLAVNHLEAHALTARMTDGIAFPYLLLLASGGHTQLVAVKGVGEYVRLGTTIDDAIGEAFDKAAKLLGLAYPGGPEVERAAEGGDPERFALPRPMLGRREPNFSLSGLKTALRIEAERIAPLSGQDVADLCASFQAAVVDVVVDRVRVALRAFGDVAGHPTALVAAGGVAANAALRRALSQLAGEAGLPLVAPPLPLCGDNGAMIAWAGLERLRLGLVDDITAPARPRWPFAEPLATAG
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANM6_XENLA
Sequence: MALLKKRKHERSEQDQEYFQCYSDVSIHEEMIADTVRTNGYKQAILHNHCALQGLTVLDVGAGTGILSVFCVQAGATRVYAVEASAVSQLASHVVTLNGMDNKVKVLNSPVESAEIPEQVDAIVSEWMGYALMYESMLPSVIYARDKWLKPGGIILPSAADLFIAPINDRVVESRLDFWNEVKGLYGVDMSCMRPFAHSCIMNKEMAVNLLSPEDVLSFPVRFASLDLNVCTQEEVRNLHGSFQFSCFGSSLLHGFALWFTVTFPGEKTVTLSTSPYGEETHWKQTLLYLDEEIQVEQDTDITGDITLSPSDVNPRHLRALLNYSIGGGLRRTKHFHMGT
What is the function of this protein?
Arginine methyltransferase that can catalyze the formation of both omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA), with a strong preference for the formation of aDMA.  Preferentially methylates arginyl residues present in a glycine and arginine-rich domain and displays preference for monomethylated substrates.  Specifically mediates the asymmetric dimethylation of histone H3 'Arg-2' to form H3R2me2a.  H3R2me2a represents a specific tag for epigenetic transcriptional repression and is mutually exclusive with methylation on histone H3 'Lys-4' (H3K4me2 and H3K4me3).  Acts as a transcriptional repressor of various genes such as HOXA2, THBS1 and TP53.  Repression of TP53 blocks cellular senescence.  Also methylates histone H2A and H4 'Arg-3' (H2AR3me and H4R3me, respectively).  Acts as a regulator of DNA base excision during DNA repair by mediating the methylation of DNA polymerase beta (POLB), leading to the stimulation of its polymerase activity by enhancing DNA binding and processivity.  Methylates HMGA1.  Regulates alternative splicing events.  Acts as a transcriptional coactivator of a number of steroid hormone receptors including ESR1, ESR2, PGR and NR3C1.
What are the official names of this protein?
Protein arginine N-methyltransferase 6, Histone-arginine N-methyltransferase PRMT6.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT6 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: YJGA_ECODH
Sequence: MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGAEIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALDKLKNRHNQQVVLFHKLENLRDRLIDQGDDAIAEVLNLWPDADRQQLRTLIRNAKKEKEGNKPPKSARQIFQYLRELAENEG
What are the official names of this protein?
UPF0307 protein YjgA.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: RS13_YERPP
Sequence: MARIAGINIPDQKHTVIALTAIFGIGKTRSQAICVAAGIAEHVKISELSEEQIEKLRDEVAKYVVEGDLRREVTLSIKRLMDLGTYRGLRHRRGLPVRGQRTKTNARTRKGPRKPIKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: LBD_ORYSJ
Sequence: MTGFGSPCGACKFLRRKCVRGCVFAPYFCHEQGAAHFAAIHKVFGASNVSKLLAHLPLADRPEAAVTISYEAQARLRDPIYGCVAHIFALQQQVMTLQAQLASLKAAAAQGIHHQDVGATTKGGYMSAAATAADDQLGYGGYNQWCGSNGGGAPAASQPGAYSSNGGAGHGHDSITALLAAGSDYMQHSLYHAFEHSEGAGAVDDGHAAAAAFEAAAESSSCGMAASFAADESVWRSSSSGYQDCEDLQSVAYAYLNRS
What is the function of this protein?
Acts as positive regulator of adventitious (crown) root formation by promoting its initiation (PubMed:15829602, PubMed:15960615).  Acts as positive regulator of lateral root formation.  Regulated by the auxin response factor and transcriptional activator ARF23/ARF1 (PubMed:15829602).  Involved in auxin-mediated cell dedifferentiation, and may promote the initial cell division in the pericycle cells adjacent to the peripheral vascular cylinder at the base of the stem (PubMed:15960615).  May act upstream of the gene regulatory network controlling adventitious root (crown) development (PubMed:21806801).
What are the official names of this protein?
LOB domain-containing protein CRL1, Protein ADVENTITIOUS ROOTLESS 1, OsARL1, Protein CROWN ROOTLESS 1.
What is the protein family that this protein belongs to?
Belongs to the LOB domain-containing protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DHRS7_DICDI
Sequence: MFFYKIIYFIGFPYIVLRLIVSIILPIASLYFIYCNFIAPKLREKPESSYKNKVVIITGASSGIGAELAKKYARLGCKVTIVARRLDQLEKVKSSFLKDYSRVNDDDILVIKGDLTLIDDCKNMVEKVIEKWSKIDICVWNAGSGSLIEFSKLQGDISIYRDNMELNYFSLVNCTHLVYKYLEQSHGSIIVISSLAGKFGTALRTSYSSSKHAVMGFFNSLRNETKNIQITIVCPGFILTEFHDNLKTLDGKQVERNKGNFMTASQCANEIILAERQGIRELIQTAKGRVGNYLQAIFPELIEFLTHKFASSSVKK
What is the function of this protein?
Putative oxidoreductase.
What are the official names of this protein?
Dehydrogenase/reductase SDR family protein 7-like.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass type II membrane protein.
Protein: DIG2_YEAST
Sequence: MNKEEQEDPQQEQISTVQENDPRNLQQLGMLLVSPGLDEDRLSEKMISKIKKSRDIEKNQKLLISRLSQKEEDHSGKPPTITTSPAEKTVPFKSLNHSLKRKRVPPALNFSDIQASSHLHGSKSAPPNITRFPQHKNSLRVRYMGRMAPTNQDYHPSVANSYMTATYPYPYTGLPPVPCYPYSSTPTQTHAYEGYYSPMYPGPLYNNGIIPADYHAKRKKLAGRSPHLEDLTSRKRTFVSKHHNGDPIISKTDEDIECSVTKNSLSEGASLNDDADDDNDKERIIIGEISLYDDVFKFEVRDDKNDYMKACETIWTEWHNLKK
What is the function of this protein?
DIG2 and DIG1 are negative regulators of the filamentation and pheromone induced mating program.  DIG1 and DIG2 inhibit the transcriptional activity of STE12 by direct protein-protein interaction.  DIG2 binds to the DNA binding domain (DBD) of STE12 and thus inhibits transcription when overexpressed.
What are the official names of this protein?
Down-regulator of invasive growth 2, Regulator of STE12 protein 2, Regulator of sterile twelve 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: TX20A_AGEAP
Sequence: EACAGAYKSCDKVKCCHDRRCRCNIAMDNCVCKLFYCELFGTCDRLKP
What is the function of this protein?
The toxin blocks voltage-gated calcium channels in rat cerebellar granule cells (IC(50)=200 nM).
What are the official names of this protein?
Omega-agatoxin-Aa5a, Omega-AGTX-Aa5a, Peptide J2.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 02 (plectoxin) family.
Protein: FIM11_SALTM
Sequence: MRHKLMTSTIASLMFVAAAAVAADPTPVSVVGGTIHFEGKLVNAACAVSTKSADQTVTLGQYRTASFTAIGNTTAQVPFSIVLNDCDPKVAATAAVAFSGQADNTTPNLLAVSSADNSTTATGVGIEILDNTSSPLKPDGATFSAKQSLVEGTNTLRFTARYKATAAATTPGQANADATFIMKYE
What are the official names of this protein?
Fimbrial subunit type 1.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: DIRC2_XENLA
Sequence: MGLEWSSPGERQPLLFPGGPRSPRVFGRRWLVLLLFSVLAFLQGLVWNSWGPIQISARTAYKFSGLDIALLVLWGPIGFLPCFLFMWLMDNRGLRITVLLTALLMVLGAGLRCVPVEDLAIRRILIHGGQLLNGFAGPTVMNAAPFLSTTWFAPDERATATAIASMLNYLGGACAFLVGPLVVPAPNSTSGLLLYSGSTDAIKDRIEAVMYAEFGIIFVVFAAILAYFPARPPVPPSVAAASRRLSYRTSIFRLLSNLRFLLIVLAYAIPLGFYSGWIGVLDLILTPVHVTQVDAGWVGFWSIVGGCVVGIAVGRFADSIRGVLKPILLLLFSGATLSATWFTLTFLSNVTHLPLTTATLYTSCILIGVFLNGTVPIFFELFVETVYPIPEGIACGVVTFLSNIFMGVLLVFLTMYQMELSWLNWCLTGSCFLSLFFIACFRESYDRLYLDVFVSV
What is the function of this protein?
Electrogenic metabolite transporter.
What are the official names of this protein?
Solute carrier family 49 member 4 homolog, Disrupted in renal carcinoma protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.
Protein: PGS2_PIG
Sequence: MKATIVFLLLAQVSWAGPFQQKGLFDFMLEDEASGIGPEDRFPEVPELEPLGPMCPFRCQCHLRVVQCSDLGLDKVPKDLPPDTALLDLQNNKITEIKDGDFKNLKNLHTLILINNKISKISPGAFAPLVKLERLYLSKNQLKELPEKMPKTLQELRVHENEITKVRKAVFNGLNQMIVVELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITTIPQGLPPSLTELHLDGNKISKVDAASLKGLNNLAKLGLGFNSISTVDNGSLANTPHLRELHLNNNKLNKVPGGLAEHKYIQVVYLHNNNISAVGSNDFCPPGYNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK
What is the function of this protein?
May affect the rate of fibrils formation.
What are the official names of this protein?
Decorin, Bone proteoglycan II, PG-S2.
What is the protein family that this protein belongs to?
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RGPS2_MACFA
Sequence: MDLMNGQASNVNIAATASEKSSSSESLSDKGSELKKSFDAVVFDVLKVTPEEYAGQITLMDVPVFKAIQPDELSSCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKTTFEKLEYVMSKEDNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILENEQRSNLMNNILRIISDLQQSCEYDIPMLPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEPGTSTPRSAASREDLVGPEVGASPQSGRKSVAAEGALLPQTPPSPRNLIPHGHRKCHSLGYNFIHKMNTAEFKSATFPNAGPRHLLDDSVMEPHAPSRGQAESSTLSSGISIGSSDGSELSEETSWPAFESSAESEDLAVHLYPGAVTIQGVLRRKTLLKEGKKPTVASWTKYWAALCGTQLFYYAAKSLKATERKHFKSTSNKNVSVVGWMVMMADDPEHPDLFLLTDSEKGNSYKFQAGNRMNAMLWFKHLSAACQSNKQQVPTNLMTFE
What is the function of this protein?
Guanine nucleotide exchange factor for the small GTPase RALA.  May be involved in cytoskeletal organization.  May also be involved in the stimulation of transcription in a Ras-independent fashion.
What are the official names of this protein?
Ras-specific guanine nucleotide-releasing factor RalGPS2, Ral GEF with PH domain and SH3-binding motif 2, RalA exchange factor RalGPS2.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Associates with membranes through the PH domain.
Protein: UBIB_BURP0
Sequence: MRIFRFVKIVFTVIRFGLDEVMLSRIENPRVKLLLRITTIGRRFADPPAVRLRRALESLGPIFVKFGQVLSTRRDLLPVDFANELAKLQDQVPPFDSAVAIAIVEKSLGARIDVLFDEFERVPVASASIAQVHFAKLKQGEHKGKAVAVKVLRPNMLPVIDSDLALMRDIATWAERLWADGRRLKPREVVAEFDKYLHDELDLMREAANGSQLRRNFAGLDLLLVPEMFWDYSTPAVLVMERMTGVPISQVDTLRAAGVDIPKLAREGVEIFFTQVFRDGFFHADMHPGNIQVSLDPKHFGRYIALDFGIVGALSDFDKNYLAQNFLAFFKRDYHRVATLHLESGWVPPDTRVEELESAIRAVCEPYFDRALKDISLGQVLMRLFSTSRRFNVEIQPQLVLLQKTMLNVEGLGRSLDPELDLWKTAKPYLERWMTEQIGLRGWYERFKVEAPQWSKTLPQLPRLVHQALISHHEAPRAISDDLIRQILVEQRRTNRLLQALLVFGLAVGAGAVIARVLIVLAYGG
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RL3_RHORT
Sequence: MRSGLIAQKVGMTRLFTDEGTHVPVTVLKVEACQVVAVRTSETDGYTAVQLGAGVAKVKRTSKAMRGHFAAAKVEPKKKVVEFRVSEDCLLEPGAELSAAHFVAGQKVDIAGTTIGKGFAGAMKRHNFRGLEATHGVSVSHRSHGSTGQCQDPGRVFKGKKMAGHMGDTRITQQSLTVVATDADRGLILVKGSVPGADGAWLEVRDAVKKKLPEGVPLPAGLKAAVEAAVDGEKE
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RL18_GRABC
Sequence: MPSIDLQERRKQRLRFQLRAKANGRPRLSVFRSGRHIYAQVIDDAAGRTLAAASSLEKPLREQLRTGADREAASAVGKLIAERAQAAGVSAVVFDRGSYLYHGRVKALAEAAREGGLAF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: PSD_ECO57
Sequence: MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKYYKVDMKEAQKPDTASYRTFNEFFVRPLRDEVRPIDTDPNVLVMPADGVISQLGKIEEDKILQAKGHNYSLEALLAGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYVPGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTITPPREGIIKRWTWPAGENDGSVALLKGQEMGRFKLGSTVINLFAPGKVNLVEQLESLSVTKIGQPLAVSTETFVTPDAEPAPLPAEEIEAEHDASPLVDDKKDQV
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MOAC_BURL3
Sequence: MSGLTHFDASGHAHMVDVGGKQETQRIAIARGTIRMLPATFALIRDGKAKKGDVLGVARIAAIQGAKRTADLIPLCHPLALTRVAVDFELDDALPGVHCVVQVETFGRTGVEMEALTAVQVGLLTVYDMCKAVDRGMVITDVSVREKRGGKSGDWKAEDTAG
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: CYB_OTOMR
Sequence: MTNIRKSHPLIKIVNDALIDLPAPSNISSWWNFGSLLGVCLAVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWLLRYLHANGASMFFICLYLHVGRGLYYGSYTYTETWNVGIILLFAVMATAFKGYVLPWGQKSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFLLPFIIAAMVMVHLLFLHETGSNNPTGIPSYFDMIPFHPYYTIKDILGFFLMLMALLMLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILMIVPILHTSKQRSMTFRPLSQCLFWLLVADLLTLTWIGGQPVEHPYIIIGQLASILYFSIILLLMPLTSLMENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SPHX_SYNE7
Sequence: MTTLKPALRRAAVLLPIAAVASSLFPIQEASAQRALVTADGSSTVFPISEAVAEEFQKRNKNINVTVGVSGTGGGFKRFCNGEIDIANASRPIKKEEVEACRKKGIRYIELPVAFDALTVVVNKSNPVNSITTAELAKIFGRDAEKKTTNWRQVKSSFPNLPLRVYAPGTDSGTYDYFNEAILNKKGTRGDLTASEDDNILVQGVSRDRGGIGFFGFSYYEENKGKLKALAVVNSNGKAVMPSVQNVLNGTYDPLARPVFIYVSEQAAKKANVRSFVNFYLQNAGKLSREVGFVPLPAKAYTAATQRFRSNKTGTVFAGKSLVGGSIEDLLKAEGIN
What is the function of this protein?
May be involved in the system for phosphate transport across the cytoplasmic membrane.
What are the official names of this protein?
Protein SphX.
What is the protein family that this protein belongs to?
Belongs to the PstS family.
What are the subcellular locations of this protein?
Cell inner membrane. Note=Found in the cytoplasmic membrane in a form that is closely associated with the cell wall.
Protein: NAV1_HUMAN
Sequence: MLGSSVKSVQPEVELSSGGGDEGADEPRGAGRKAAAADGRGMLPKRAKAPGGGGGMAKASAAELKVFKSGSVDSRVPGGPPASNLRKQKSLTNLSFLTDSEKKLQLYEPEWSDDMAKAPKGLGKVGSKGREAPLMSKTLSKSEHSLFQAKGSPAGGAKTPLAPLAPNLGKPSRIPRGPYAEVKPLSKAPEAAVSEDGKSDDELLSSKAKAQKSSGPVPSAKGQEERAFLKVDPELVVTVLGDLEQLLFSQMLDPESQRKRTVQNVLDLRQNLEETMSSLRGSQVTHSSLEMTCYDSDDANPRSVSSLSNRSSPLSWRYGQSSPRLQAGDAPSVGGSCRSEGTPAWYMHGERAHYSHTMPMRSPSKLSHISRLELVESLDSDEVDLKSGYMSDSDLMGKTMTEDDDITTGWDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTDSEKRSLAESGLSWFSESEEKAPKKLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKKPISLGHPGSLKKGKTPPVAVTSPITHTAQSALKVAGKPEGKATDKGKLAVKNTGLQRSSSDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVPDLHATSSASGGPLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSSTPVPTPPAPPAAPTEEETEELTWSGSPRAGQLDSNQRDRNTLPKKGLRYQLQSQEETKERRHSHTIGGLPESDDQSELPSPPALPMSLSAKGQLTNIVSPTAATTPRITRSNSIPTHEAAFELYSGSQMGSTLSLAERPKGMIRSGSFRDPTDDVHGSVLSLASSASSTYSSAEERMQSEQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVIQGALNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKKSWVYELRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPSIKSSTSSSVGTDVTEGPAHPAPHTRLFHANEEEEPEKKEVSELRSELWEKEMKLTDIRLEALNSAHQLDQLRETMHNMQLEVDLLKAENDRLKVAPGPSSGSTPGQVPGSSALSSPRRSLGLALTHSFGPSLADTDLSPMDGISTCGPKEEVTLRVVVRMPPQHIIKGDLKQQEFFLGCSKVSGKVDWKMLDEAVFQVFKDYISKMDPASTLGLSTESIHGYSISHVKRVLDAEPPEMPPCRRGVNNISVSLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLVLSGPSGTGKTYLTNRLAEYLVERSGREVTEGIVSTFNMHQQSCKDLQLYLSNLANQIDRETGIGDVPLVILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLHLSFRMLTFSNNVEPANGFLVRYLRRKLVESDSDINANKEELLRVLDWVPKLWYHLHTFLEKHSTSDFLIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGIKVHGQKAAWEDPVEWVRDTLPWPSAQQDQSKLYHLPPPTVGPHSIASPPEDRTVKDSTPSSLDSDPLMAMLLKLQEAANYIESPDRETILDPNLQATL
What is the function of this protein?
May be involved in neuronal migration.
What are the official names of this protein?
Neuron navigator 1, Pore membrane and/or filament-interacting-like protein 3, Steerin-1, Unc-53 homolog 1, unc53H1.
What is the protein family that this protein belongs to?
Belongs to the Nav/unc-53 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Associates with a subset of microtubule plus ends. Enriched in neuronal growth cones (By similarity).
Protein: AP2A_RAT
Sequence: MLWKLTDNIKYEDCEDRHDGTSNGTARLPQLGTVGQSPYTSAPPLSHTPNADFQPPYFPPPYQPIYPQSQDPYSHVNDPYSLNPLHAQPQPQHPGWPGQRQSQESGLLHTHRGLPHQLSGLDPRRDYRRHEDLLHGPHGLGSGLGDLPIHSLPHAIEDVPHVEDPGINIPDQTVIKKGPVSLSKSNSNAVSAIPINKDNLFGGVVNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSSPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAVAEFLNRQHSDPNEQVARKNMLLATKQICKEFTDLLAQDRSPLGNSRPNPILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYLTEALKAMDKMYLSNNPNSHTDNSAKSSDKEEKHRK
What is the function of this protein?
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes.  AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development.  They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and c-Myc.  AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle.  Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation.  Associates with chromatin to the PITX2 P1 promoter region (By similarity).
What are the official names of this protein?
Transcription factor AP-2-alpha, AP2-alpha, AP-2 transcription factor, Activating enhancer-binding protein 2-alpha, Activator protein 2, AP-2.
What is the protein family that this protein belongs to?
Belongs to the AP-2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARAG_YERPS
Sequence: MSAPHSALQAELDAAQSPYLAFRGIGKSFPGVLALDDISFTCQAGQIHALMGENGAGKSTLLKILSGNYTPTQGEIHIKGKAVNFTNTTDALDAGVAIIYQELHLVPEMTVAENIYLGQLPTKMGMVDRKLLRYESRIQLSHLGLDIDPDTPLKYLSIGQWQMVEIAKALARNAKIIAFDEPTSSLSAREIEQLFRVIRELRAEGRVILYVSHRMEEIFALSDAITVFKDGRYVRTFDDMTQVNNASLVQAMVGRNLGDIYGYQPREIGSERLTLQAVKAIGVASPISLTVHQGEIVGLFGLVGAGRSELLKGLFGDTKLTSGKLLLDGQPLTIRSPIDAISAGIMLCPEDRKADGIIPVHSVQDNINISARRKTLTAGCLINNRWEADNALLRIQSLNIKTPGPQQLIMNLSGGNQQKAILGRWLSEDMKVILLDEPTRGIDVGAKHEIYNVIYQLAKQGIAVLFASSDLPEVLGLADRIVVMREGAISGELDHEYATEEQALSLAMLRTPNIATNTASAVA
What is the function of this protein?
Part of the ABC transporter complex AraFGH involved in arabinose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Arabinose import ATP-binding protein AraG.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RF3_ALISL
Sequence: MSFLQEVGKRRTFAIISHPDAGKTTITEKVLLFGNAIQKAGTVKGRGSNQHAKSDWMEMEKERGISVTTSVMQFPFNGCLVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDAAKGVEDRTRKLMEVTRLRDTPIVTFMNKMDREVRDPMEVLDEVESELGMACAPISWPIGCGKEFKGVYHIHRDETILYQSGHGHEIQEVRTIKGLDNPELDVAIGNELALSVREELELVIGAAHEFDLELFLKGELTPVYFGTALGNFGVDHMLEGLTEWAPAPQTREATERPVEATEEKFSGFVFKIQANMDPKHRDRIAFMRIVSGTYTQGMKMNHVRTGKNISISDAVTFMAGDRARAEVAYAGDIIGLHNHGTIQIGDTFTQGENLKFSGIPNFAPELFRRIRLRDPLKQKQLLKGLVQLSEEGAVQVFRPLQNNDLIVGAVGVLQFDVVVSRLKSEYNVEAIYEGISVATARWVECSDGKMQDEFQRKNQTNLALDGGNNLTYIAPTMVNLNLAIERFPDVQFRATREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SL1_CRODU
Sequence: MGRFIFVSFGLLVVFLSLSGTGADFDCPSGWSAYDQYCYRVIKQLKTWEDAEWFCTKQAKGAHLVSVESAGEADFVAQLVAENIKQNKYYVWIGLRIQNKGQQCSTKWSDGSSVNYENLLKSYSKKCFGLKKETEFLQWYNTDCEEKNLFVCKFPPQR
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec crotocetin-1, CRC1.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: CRH12_CANAL
Sequence: MYKQILTFLILFLRYILSEFPDDPYEDDDTSDDNNSDYEGQKCNPYRDKACLVNDEALGKKIFESFAEGTKYFTITSSTRGVRFGSEGLALTIQDEFDNPALVSSFYIMYGKVEAEIKGAAGKGIISSFYLQSDDLDEIDVVEIFGSDPYEFQTNFFIKGNTTTYDRGRYHEMHPSPLSEFHKYGIEWSPDLITWYLDDKPVRMLGRRNKHGLPCSPMFLKFSLWSVEDDDEGTIAWAGGAASFSEGPFTMHIKNLKVQDYSKALTYSYGNLRDGNWLDLRADGGYLYEGHKYCLPPKMLDKLKPTPKQETDDDQVLTSSKSQRVATTISEDKNTVSYYPPSATNSHTTWDRLSEWETEQDETGTDDTENSDNEEEESITAIPISKSRKGSTRRLDISTQLPPLSQNESKIAEIKNITTTKHIHNTTTSLQISKIKSKKVGVTTTIYSSSTPQSTSKSRMPYNIFFNYPGKENSRFKSGVSSILATSFSSVVIAEILVIVVLLL
What is the function of this protein?
Extracellular glycosidase which plays an important role in fungal pathogenesis.  Involved in cell wall assembly and regeneration, filamentation, and adherence to host cells.
What are the official names of this protein?
Extracellular glycosidase CRH12, Congo red hypersensitive protein 12.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family. CRH1 subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Note=Covalently-linked GPI-modified cell wall protein (GPI-CWP).