PharMolix/UniProtQA huggingface dataset:
Protein: NDHH_THEVB
Sequence: MPKIETRTEPMVINMGPHHPSMHGVLRLMVTLDGEDVIDCEPVIGYLHRGMEKIAENRTNIMFIPYVSRWDYAAGMFNEAVTVNAPEKLAGIPVPKRASYIRVIMLELNRIANHLLWLGPFLADVGAQTPFFYIFREREYIYDLFEAATGMRFINNNYFRIGGVAADLTYGWVTKCRDFCDYFLPKVDEYERLITNNPIFVRRLQGVGKISREEAINWGLSGPMLRASGVKWDLRKVDHYECYDDFDWDVPVATEGDCLARYIVRIQEMRESVKIIRQALDGLPGGPYENLEAKRMLEGAKSEWNGFDYQYIGKKLSPTFKIPKGEHYVRVESGKGELGIYLIGDDNVFPWRWKIRPPDFNNLQVLPQLLKGMKVADIVAILGSIDVIMGSVDR
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase subunit H, NDH-1 subunit H, NDH-H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RISB_METMJ
Sequence: MTVKLGFVVAEFNRDITYMMEIEAREHAGFLDAEVADTIYVPGAYDMPLAIKKLLERGEIDAVVTIGCVIEGATQHDEIVVQHAARKIIDLSLEFGKPVALGISGPGMTRMEATERIDYAKRAVESAVKMVQRLE
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: CYF_PLETE
Sequence: MTTFFISKVNGPVNKSLIWLKIHIYEFFLLKFMLLFPPTVCSTNPDCFKSNRIVNCFLDESPYFFRWVGFSLQKTQVAKIILCLIAVICCELSLTSNQINTSQAYPIFAQQNYENPREATGRIVCANCHLAQKPVELSLPQAVMPDTVFEAVVKIPYDQEIQQVLGNGKKGGLNVGAVLILPEGFSLAPPDRIPEEMKNKVGKLYFQSYNPEKPNILVIGPVPGKTYNEMVFPILSPNPETNKNISYLKYPIYLGGNRGRGQIYPDGSKSNNTVYNASTGGTIVDITPASKKGGYNLTIETANGEQIVDKIPPGPELIVSVGQSIKPDQALTNNPNVGGFGQQDGEIVLQNPVRLQALIVFFIFVILTQLFLVLKKKQFEKVQLAEMNF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SYR_IDILO
Sequence: MKEQLEQLLAEAIGQLKAQGTIPADHSVNIQLDRPRDKSHGDFATNLALMLAKPAKSNPRQLAEAIVAAVPENSLLSKMDIAGPGFINFTISQDQLKDQLTAMLNSDSLNVDVAEESKTIVIDYSSPNLAKEMHVGHLRSAIIGDAVSRVCEFLGHKVIRQNHVGDWGTQFGMLLAYMEALDNQSAEYELSNLETFYKAAKQRFDESEEFADRARQLVVKLQSGDEYCLKLWNQFIDVSLSHCQDVYDRLGVKLTRDDVMAESAYNDKLPGVIEHLREKGLLTEDQGAQCVFLEEYKGKEGEPLPIIVQKKGGGYLYATTDLAAIEYRQKELGGDHLMYFVDARQALHFDQIFTLARKAGFVEGDIQLNHYGFGTVMGKDGKPYKSRDGGVTKLADLLDEAERRALELLQQKTTDLSEEQQKRVAEVVGISSVKYADLSKNRTSDYVFDWNHMLTFEGNTAPYLLYAFTRVNSIFDRLGDTAFDRNADIILSDERELALANQLVRFNEVLHQVQDKAMPHFLCGFLFDLAGRFSSFYEACPILNQEDEALRNSRLKLSMLTANVLKQGLELLGIPTLEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M3K13_PONAB
Sequence: MANFQEHLSCSSSPHLPFSESKTFNGLQDELTAMGNHPSPKLLEDQQEKGMVRAELIESVHSPVTTTVLTSVSEDSRDQFENSVLQLREHDESEMAVSQGNSNTVDAESTSGTEDIKIQFSRSGSGSGGFLEGLFGCLRPVWNIIGKAYATDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRAEEVAIKKVREQNETDIKHLRKLKHPNIIAFKGVCTQAPCYCIIMEYCAHGQLYEVLRAGRKITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKELSDKSTKMSFAGTVAWLAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTLMHLDIASADVLATPQETYFKSQAEWREEVKKHFEKIKSEGTCIHRLDEELIRRRREELRHALDIREHYERKLERANNLYMELSAIMLQLEMREKELVKREQAVEKKYPGTYKRHPVRPIIHPNAMEKLMKRKGVPHKSGMQTKRPDLLRSEGIPTTEVAPTASPLSGSPKMSTSSSKSRYRSKPRHRRGNSRGSHSDFVAILKNQPAQENSPNPTYLHQAQSQYPSLHHRNSLQQQYQQPPPAMSQSHHPRLNMHGQDIATCANNLRYFGPAAALRSPLSNHAQRQLPGSSPDLISTAMAADCWRGSEPDKDQAGPWGCCQADPYDPCLQCRPEQYGSLDIPSAEPVGRSPDLSKSPAHNPLLENAQSSEKMEENEFSSCRSESSLGTSHLVTPPALPRKTRPLQKSGDDSSEEEEGEVDSEVEFPRRQRPHRCISSCQSYSTFSSENFSVSDGEEGNTSDHSNSPDELADKLEDRLAEKLDDLLSQTPEIPIDISSHSDGLSDKECAVRRVKTQMSLGKLCVEERGYENPMQFEESDCDSSDGECSDATVRTNKHYSSATW
What is the function of this protein?
Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7.  Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol.  This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B (By similarity).
What are the official names of this protein?
Mitogen-activated protein kinase kinase kinase 13.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: P2C67_ORYSJ
Sequence: MAHQKREATSDNGGGDEEWASKRPKVVGAAAEKEHILTSDASHETNGDEAQGGDASRKENTVSTNPCVSDEKAATNSNVSSGHGVILTSVEADAAEDKGCRHTMEDAWVLLPDASMESPGNLRCAHFAIYDGHGGRLAAEYAQKHLHQNVIAAGLPRELMDVKAAKKAIIEGFRRTDECLLQESTKGNWQDGATAVCVWVLGQTVVVANAGDAKAVLARSTSADGEGAVDDAKSQLKAIVLTREHKAIFPQERARIQKAGGSVGPNGRLQGRIEVSRALGDRQFKKVGLIATPDVHSFEVTRKDHFIILGCDGLWGVFGPGDAVEFVQNQLKETSSATLAVRRLVKEAVRERRCKDNCTAVLIVFKH
What are the official names of this protein?
Probable protein phosphatase 2C 67, OsPP2C67.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: RPOA_POLAQ
Sequence: MQTNLLKPKIISVEALTANQAKVVMEPFERGYGHTLGNALRRVLLSSMVGYAPTEVAIAGVVHEYSTLDGVQEDVVNLLLNLKGIVFKLQSRDEVTINLRKEGPGVVTAKDIDLPHDVEIMNPDHVIAHLSAGGKLDMQIKVEKGRGYVPGNVRQYNDETTKIIGRIVLDASFSPVSRVSYAVESARVEQRTDLDRLVMTIETNGVLSPEEAIRQAASILVDQLVVFAALESSEVSGDLAPSRSSMVDPMLMRPVDDLELTVRSANCLKAENIYYIGDLIQRTENELLKTPNLGRKSLNEIKDVLAARGLSLGMKLESWPPANLEK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: KDPA_STAA8
Sequence: MEIILFLTMMVMITYVFSGYLYRVALVQSSRVDLIFTRFENMCFKIIGTDLEHMSAKTYVKHFLAFNGFMGFITFVLLIVQQWLFLNPNHNLNQSIDLAFNTAISFLTNSNLQHYNGESDVTYLTQMIVMTYLMFTSSASGYAVCIAMLRRLTGLTNIIGNFYQDIVRFIVRVLLPLSCLISILLMTQGVPQTLHANLMIRTLSGHIQHIAFGPIASLESIKHLGTNGGGFLAGNSATPFENPNIWSNFIEMGSMMLLPMSMLFLFGRMLSRHGKRVHRHALILFVAMFFIFIAILTLTMWSEYRGNPILANLGIYGPNMEGKEVRFGAGLSALFTVITTAFTTGSVNNMHDSLTPIGGLGPMVLMMLNVVFGGEGVGLMNLLIFVLLTVFICSLMVGKTPEYLNMPIGAREMKCIVLVFLIHPILILVFSALAFMIPGASESITNPSFHGISQVMYEMTSAAANNGSGFEGLKDDTTFWNISTGIIMLLSRYIPIILQLMIASSLVNKKSYHQDKYTIAIDKPYFGVSLIVFIVLLSGLTFIPVLLLGPIGEFLTLK
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HSP76_HUMAN
Sequence: MQAPRELAVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHNTVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEEISSMVLSKMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVNHFMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNATIPTKQTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQICRPIFSRLYGGPGVPGGSSCGTQARQGDPSTGPIIEEVD
What is the function of this protein?
Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes.  Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation.  This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones.  The affinity for polypeptides is regulated by its nucleotide bound state.  In the ATP-bound form, it has a low affinity for substrate proteins.  However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins.  It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release (PubMed:26865365).
What are the official names of this protein?
Heat shock 70 kDa protein 6, Heat shock 70 kDa protein B'.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: HIS8_BRUME
Sequence: MQKPTRPQPKAGVLDIAAYVPGKEHVEGVAKVYKLSSNETPLGPSPHAREAYRHAGEKLELYPDGQALALRQAIAETQGLNISNILCGNGSDELLGLLCQTYLAPGDETIITEHGFAVYKIQTLAAGATPVTVKEKNERIDVDAILAGVTARTKIVFIANPANPTGTYLPFEEVRRLHAGLPQHVLLVLDAAYAEYVRRNDYEAGLELVSSNENVVMMRTFSKIHGLPGLRIGWIYAPLHIIDAMNRIRGPFNMNSAAIAAGAAAIRDRAHVEKSVAYNEKWLAWLTEEFTRLGLRVTPSVTNFLLIHFPDDAAHSADKADEWLSRRGYILRRVGGYGFPNALRMTVGPEEANRGVVAALTEFLK
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: Y1312_MYCBO
Sequence: MSPLLEVTDLAVTFRTDGDPVTAVRGISYRVEPGEVVAMVGESGSGKSAAAMAVVGLLPEYAQVRGSVRLQGTELLGLADNAMSRFRGKAIGTVFQDPMSALTPVYTVGDQIAEAIEVHQPRVGKKAARRRAVELLDLVGISQPQRRSRAFPHELSGGERQRVVIAIAIANDPDLLICDEPTTALDVTVQAQILDVLKAARDVTGAGVLIITHDLGVVAEFADRALVMYAGRVVESAGVNDLYRDRRMPYTVGLLGSVPRLDAAQGTRLVPIPGAPPSLAGLAPGCPFAPRCPLVIDECLTAEPELLDVATDHRAACIRTELVTGRSAADIYRVKTEARPAALGDASVVVRVRHLVKTYRLAKGVVLRRAIGEVRAVDGISLELRQGRTLGIVGESGSGKSTTLHEILELAAPQSGSIEVLGTDVATLGTAERRSLRRDIQVVFQDPVASLDPRLPVFDLIAEPLQANGFGKNETHARVAELLDIVGLRHGDASRYPAEFSGGQKQRIGIARALALQPKILALDEPVSALDVSIQAGIINLLLDLQEQFGLSYLFVSHDLSVVKHLAHQVAVMLAGTVVEQGDSEEVFGNPKHEYTRRLLGAVPQPDPARRG
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein Mb1312c.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: GCSPA_LEGPL
Sequence: MPYIPHTPNDTKEMLAAIGAQDIQDLFDEIPASLQYAGFQNIPAGINEMEMLKEAQNQAQKNRNGICFIGAGCYEHHIPAAVWDIASRGEFLTAYTPYQAEASQGTLQLLYEYQTMICELTGMEVSNASMYDGATALAEAVLMAVRLNKHSKTNRVLIAGTVHPFYRETIETIVRNQHIEVITLPFDEQQGITDLGSLNQYTGEDITALVIAQPNFFGCLEQVDKMTSWAHHNKTISVACINPTSLALLKPPGSWGEHGVDIVCGEGQPLGSPMASGGPYFGFLSTRMAHVRQMPGRIIGRTVDKDGKTGFSLTLQAREQHIRRAKATSNICTNQGLLVTAATIYMSLLGPEGLSQVATQCHQNTHELITALTQIEGVEQAFKASFFHEALIKLNQPVQSVLQQLADAGIAGGYAPEQHYPQLANTLLVCATEVRTAEDIAKYAKTLKAIMSKRGA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: RL28_SALTI
Sequence: MSRVCQVTGKRPVTGNNRSHALNATKRRFLPNLHSHRFWVESEKRFVTLRVSAKGMRIIDKKGIETVLSELRARGEKY
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: HAKAI_MOUSE
Sequence: MDHTDNELQGTNSSGSLGGLDVRRRIPIKLISKQASKVKPAPRTQRTVSRMPAKAPQGDEEGFDYNEEQRYDCKGGELFGNQRRFPGHLFWDFKINILGEKDDTPVHFCDKCGLPIKVYGRMIPCKHVFCYDCAILHEKKGDKMCPGCSDPVQRIEQCTRGSLFMCSIVQGCKRTYLSQRDLQAHINHRHMRAGKPVTRASLENVHPPIAPPPTDIPDRFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSSSGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRMQGPPSQTPLPGPHHPDQTRYRPYYQ
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination of several tyrosine-phosphorylated Src substrates, including CDH1, CTTN and DOK1 (PubMed:11836526, PubMed:22252131).  Targets CDH1 for endocytosis and degradation (PubMed:11836526).  Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing (PubMed:29535189, PubMed:29547716).  Its function in the WMM complex is unknown (PubMed:29535189, PubMed:29547716).
What are the official names of this protein?
E3 ubiquitin-protein ligase Hakai, Casitas B-lineage lymphoma-transforming sequence-like protein 1, c-Cbl-like protein 1, E-cadherin binding protein E7, RING-type E3 ubiquitin transferase Hakai.
What is the protein family that this protein belongs to?
Belongs to the Hakai family.
What are the subcellular locations of this protein?
Nucleus speckle. Nucleus, nucleoplasm. Cytoplasm. Note=Mainly nuclear with some fraction located in the cytoplasm (PubMed:29547716). ZC3H13 is required to anchor component of the MACOM subcomplex, such as VIRMA, in the nucleus (PubMed:29547716).
Protein: RLMN2_OPITP
Sequence: MRFLTGNVVVRARGADFFVAIDARSAGGADAWLALTNGAPLLRRFTLSPSAPTNLYDFTRAELRLWLSRRELNPVHAARIWSYLYLDLVEGFGAMTELPARVRARLEAEMCVGNLKIARETDSRDGFTRKYLLELADGAAIETVLMRFAGRATACVSSQVGCAMGCVFCATGQMGYTRHLTAGEIVAQAVHVARALRTAAFEKCHVMRDPSPGREAGEKSRDEADRHRAPPTPRLRNLVLMGMGEPLHNYEAVMRAVDILRDDGGLALGAERITLSTVGVVPGILRLAAEKRPVHLAVSLHAADQEERAALVPVAKKWPLDELMAACRTYSETTGRRVFYEWTLIEGRNDTAAHARAVGRLLRGLPAQVNLIPLNPTAGYDGTPGRTEAARRFQEILSREFALPSTVRQRRGIDIAAGCGQLAVAEQS
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN 2, 23S rRNA (adenine(2503)-C(2))-methyltransferase 2, 23S rRNA m2A2503 methyltransferase 2, Ribosomal RNA large subunit methyltransferase N 2, tRNA (adenine(37)-C(2))-methyltransferase 2, tRNA m2A37 methyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSH_SYNP2
Sequence: MGGMMPDLDLATVNEKLSEANAVEVVQWASQTFPEGLIMSTSFGIQSAVMLHLVTQVIPDIPVVWIDTGYLPEATYRFAEELGDRLNLNLKVYQSPLSPARMEALYGKLWEQDNIEAFNRYDYIRKVEPMQRALKELNAKAWLAGLRKGQTDHRKTLGYVAKQGKQYKIHPILTWTSKDVYEYLMAHDLPYHPYFDKGYVTVGDWHSSRPLMAGDESERDTRFRGLKQECGLHLPSTSEEAQSLDSSGL
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB_PARD8
Sequence: MIKVFLLIIGGAIGSALRFGVSTWMQRSMLYSFPFGILSVNVIGSFLIGFCWSIAEAYNFSINTRAFLFTGLFGGFTTFSSFALDTMVLMRTGEYKMALLNVLASNILGLIAVFLGIILGKNIITMIK
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CUTC_RHILO
Sequence: MDWIDPLTTETRLPLIEICVEGIDGLLAAQAAGADRVELCASLVEGGITPSLGTVRAALDQATVPFHVMVRPRGGDFLYSETEYRSMLADVAALRDLGVPGVVFGCLNADGTIDEKRMGELTEAAGPLNVTCHRAFDMTRDPAEALEALIRCKVGRVLTSGQRDSAIEGLPLLADLVRQAGDRIIILGCGGLDLANIAEVRRKTGLAEMHFAALKDVPSTMRYRNPKVGMGGSDLDREYRNTLTDTPLVAATIAAAKA
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EASC_ARTOC
Sequence: MAPNAADKCPVMNNAAEKCPVMHSNGVSSIQSHGPRDIYTLEALSHFNREKIPERAVHAKGTGAYGEFEVTADISDICNVDMLLGVGKKTQCVTRFSTTGLERGSSDGVRDLKGMAVKFFTEQGDWDWVSLNFPFFFIRDPAKFPDMIHSQRRDPQTNLLNPSMTWDFVTKNPEALHMTLLQHSDFGTMFTWRTLSSYAGHAFKWVMPDGSFKYVHFFLASDRGPNFTDGSTAKIDPNDPDFATKDLFEAIERGDYPTWTANVQVIDPKDAPKLGFNILDITKHWNLGTYPKGLDTIPSRPFGKLTLNRNVKDYFTEVEKLAFSPSNLVPGVEPSEDPILQARMFAYPDAQRYRLGIDHLKAPIRRKETSCKHDLGPEFDQWLSQVTSESWSHPHEDDYKFAREYYEVLPEFRSQEFQDRMVENLYKSVAQGPEDLRKRVYETFELVSTELARRVREGAEVIVADMAQPDSPERAQPGQQRL
What is the function of this protein?
Catalase; part of the gene cluster that mediates the biosynthesis of fungal ergot alkaloid (PubMed:22403186).  DmaW catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4-dimethylallyl-L-tryptophan (PubMed:22403186).  The second step is catalyzed by the methyltransferase easF that methylates 4-dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methionine, resulting in the formation of 4-dimethylallyl-L-abrine (PubMed:22403186).  The catalase easC and the FAD-dependent oxidoreductase easE then transform 4-dimethylallyl-L-abrine to chanoclavine-I which is further oxidized by easD in the presence of NAD(+), resulting in the formation of chanoclavine-I aldehyde (PubMed:22403186).  Chanoclavine-I aldehyde is the precursor of ergoamides and ergopeptines in Clavicipitaceae, and clavine-type alcaloids such as fumiclavine in Trichocomaceae (PubMed:22403186).  However, the metabolites downstream of chanoclavine-I aldehyde in Arthrodermataceae have not been identified yet (PubMed:22403186).
What are the official names of this protein?
Catalase easC, Ergot alkaloid synthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
Protein: C3AR_MOUSE
Sequence: MESFDADTNSTDLHSRPLFQPQDIASMVILGLTCLLGLLGNGLVLWVAGVKMKTTVNTVWFLHLTLADFLCCLSLPFSLAHLILQGHWPYGLFLCKLIPSIIILNMFASVFLLTAISLDRCLIVHKPIWCQNHRNVRTAFAICGCVWVVAFVMCVPVFVYRDLFIMDNRSICRYNFDSSRSYDYWDYVYKLSLPESNSTDNSTAQLTGHMNDRSAPSSVQARDYFWTVTTALQSQPFLTSPEDSFSLDSANQQPHYGGKPPNVLTAAVPSGFPVEDRKSNTLNADAFLSAHTELFPTASSGHLYPYDFQGDYVDQFTYDNHVPTPLMAITITRLVVGFLVPFFIMVICYSLIVFRMRKTNFTKSRNKTFRVAVAVVTVFFICWTPYHLVGVLLLITDPESSLGEAVMSWDHMSIALASANSCFNPFLYALLGKDFRKKARQSIKGILEAAFSEELTHSTNCTQDKASSKRNNMSTDV
What is the function of this protein?
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a.  This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
What are the official names of this protein?
C3a anaphylatoxin chemotactic receptor, C3AR, C3a-R, Complement component 3a receptor 1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL20_ACIBY
Sequence: MARVKRGVVAHRRHKKILARAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQKKRQFRALWIARINAGARQNGLSYSRMIDGLKKAQVIIDRRVLADIAMHDAVAFAALAEKAKGALAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: PP133_ARATH
Sequence: MKPQMFFRSVIQFYSKPSWMQRSYSSGNAEFNISGEVISILAKKKPIEPALEPLVPFLSKNIITSVIKDEVNRQLGFRFFIWASRRERLRSRESFGLVIDMLSEDNGCDLYWQTLEELKSGGVSVDSYCFCVLISAYAKMGMAEKAVESFGRMKEFDCRPDVFTYNVILRVMMREEVFFMLAFAVYNEMLKCNCSPNLYTFGILMDGLYKKGRTSDAQKMFDDMTGRGISPNRVTYTILISGLCQRGSADDARKLFYEMQTSGNYPDSVAHNALLDGFCKLGRMVEAFELLRLFEKDGFVLGLRGYSSLIDGLFRARRYTQAFELYANMLKKNIKPDIILYTILIQGLSKAGKIEDALKLLSSMPSKGISPDTYCYNAVIKALCGRGLLEEGRSLQLEMSETESFPDACTHTILICSMCRNGLVREAEEIFTEIEKSGCSPSVATFNALIDGLCKSGELKEARLLLHKMEVGRPASLFLRLSHSGNRSFDTMVESGSILKAYRDLAHFADTGSSPDIVSYNVLINGFCRAGDIDGALKLLNVLQLKGLSPDSVTYNTLINGLHRVGREEEAFKLFYAKDDFRHSPAVYRSLMTWSCRKRKVLVAFNLWMKYLKKISCLDDETANEIEQCFKEGETERALRRLIELDTRKDELTLGPYTIWLIGLCQSGRFHEALMVFSVLREKKILVTPPSCVKLIHGLCKREQLDAAIEVFLYTLDNNFKLMPRVCNYLLSSLLESTEKMEIVSQLTNRMERAGYNVDSMLRFEILKYHRHRKQVLIDL
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g79540.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
Protein: MATK_LILHE
Sequence: MEELQEYFKKDRSPQQHFLYPLLLQEYIYTLAHDDSLNGSIFYEPIEFIGYDNKFSLVLVKRLIIRMYQQNFLIYLVNDSNQNRFGGHSNYFYSHFFYSQMVSKGFSVIVEIPFSLRLVSSSEEKEIPKSQNLGSIHSIFPFLEDKLSHLNNVSDILIPHPIHFEILVQILQCWIQDVPSLHLLRFFLHKYQNLNKTIQSNKTIYVFSKENKRLFWFLHNSYVSECEFLLVFFHKQSCYLRSTSSGAFLERSHFYGKMEHIIIVCCNNFQKTLWPVKDPLIHYVRYQGKAILASRGTHLLMKKWRYYFVNFWQYYFHFWSQPYRMHINSLLNYSFYFMGYLLGVLINPYAVKNQMLENSFLIDTVINKFDTIIPIIPLIGSLSKAKFCTFSGHPISKPIWADLLDFDIIDRFGRICRNLSHYHSGSSKKQSLYRIKYILRLSCARTLARKHKSTVRALLQRLGSGLLEEFFTEEEQVLSFFFPKTTLFTLHGSHRERIWSLDIIRINDLVNN
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NEU1_PAPHA
Sequence: PLGGKRAAPDLDVRKCLPCGPGGKGRCFGPNICCAEELGCFVGTAEALRCQEENYLPSPCQSGQKACGSGGRCAVFGLCCSPDGC
What is the function of this protein?
Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland.  Acts by binding to oxytocin receptor (OXTR) (By similarity).
What are the official names of this protein?
Oxytocin-neurophysin 1, OT-NPI.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.