PharMolix/UniProtQA huggingface dataset:
Protein: LST2_DROAN
Sequence: MNGSGGRQMQCGKKADDKSLLARFFHADRSLTAVASELDSFDGRAEPDRCTRLVSKLRLNQDKVLAITNLIMEELLGEDRDPRAFRAKFPEEVLQENLAGQLWFGAECLAAGSSIMNREAESKEMRPLAQAVTKSLGNVRVLLRDQCLRNNVPNSKTLQLDLNDSTTEQLYESLKIFDRLFAEFELSYVSAMVQVKSRHEYEMQQWIGVLFSETLQRALKIGLLDQDMVDAFDPGLMFSIPRLAIVAGLVVYAKGPLNMDMPGDQLSEMFRPFRTILIKIRDLLRNLNHEELYQLEKVLCTNEDINAKAPLGSSSIEAPSPEHSSHHPTTSSNNNNNNGDTTGTTNTHRTVERLVDQRNNNNNNNTSSAPALDKAANRSPSMLSLSPNSTPTASPAPSPTPSHSIASTSSSATGSTHPPADWSDGDDEDEEDDDDDIEVEEEELDSTDDETDEEQLLKDIVAADCASGYLIPNTNLGNLLQPQEVPLTDNFVASEDDEYGAGEQQRQRHRDGQEDEPSTSAAMLAASRTLQRLRLPSSDAEPLAEQSTIKTPEQEQDQPHQSVYRHRHSHRHHHRHHHHHHQRHHHHQHQQPPQPHPHRTTRSGRKRCSLDSTESEATQPERDREPSQASGDTSAASSLSDDVSLAMRNTTARLKFKSTENLLHRLFVCIAGVADQLQTNFASDLRQILRSVFLMNMSSAQEEIDIPEKTKESELFEFRASENDVIQESAGSNQSIYSAEEVNPELDNVFSAGSGGGSPGNGNQANASAQRHSAGGSIQRNNTVDDGSPTGGGALLATSRSHVMRSRSLGDQESASTSTSSSQLHQEQQQLQIQVQRQRNNSVGSNTPSSASSTSSSSEQNSPVSARSGSRRRLQSNNETQMPSSATVTTTATATLAPPAWIPDGKAPRCMSCQTPFTAFRRRHHCRNCGGVFCGVCSNASAPLPKYGLTKAVRVCRECYVREVRSGMSVQGVPSVQERLTATAS
What is the function of this protein?
Negative regulator of epidermal growth factor receptor (EGFR) signaling.
What are the official names of this protein?
Lateral signaling target protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the lst-2 family.
Protein: DXR_ACIB5
Sequence: MTQSVCILGVTGSIGRSTLKILGQHPDKYSVFAVSAHSRISELVEICKQFRPKVVVVPEQKIAELKTLFAQQNISDIDVLAGQEGLVDIASHTDVDIVMAAIVGAAGLLPTLAAVKAGKRVLLANKEALVMSGEIMMQAARDHQALLLPVDSEHNAIFQSLPHNYLQADRTGQPQLGVSKILLTASGGPFLNHSLEQLVHVTPQQACKHPNWSMGQKISVDSATLMNKGLELIEACHLFSISEHFVTVVVHPQSIIHSMVQYVDGSTLAQMGNPDMCTPIAHALAWPERLQTNVPALDLFEYSQLNFQAPDTQKFPALNLARQAMRAGGLAPTILNAANEIAVEAFLMERIGFTSIPQVVEHTLEKLENAAAESIECILDKDKVARSVAQQYISSIGG
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: URED_STUS1
Sequence: MTVLTHPFTPHWQAELELGYTRIGDATRPVLRRHSGPLRVQKHLYPEGSEVCQHIIVHPPGGIAGGDRLDISVTLGPGAWAQLTSPGAAKWYRAASPAFQDLQLRVEAGATLEWLPQETIVYSAAQAELNTRIELHGDARLFYWDIVALGRPAAGERFDAGHFQARLDIRRDDRLIWHERQRIAGADALLDSPIGLDGRSVFATLIASGELDADLLERCRGLPSRVRGDLTQLPGLIVARCLADEALHTRAWLIDLWRLLRPALLGREAVPPRIWST
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
Protein: SCTG_SALTS
Sequence: MKKFYSCLPVFLLIGCAQVPLPSSVSKPVQQPGAQKEQLANANSIDECQSLPYVPSDLAKNKSLSNHNADNSASKNSAISSSIFCEKYKQTKEQALTFFQEHPQYMRSKEDEEQLMTEFKKVLLEPGSKNLSIYQTLLAAHERLQAL
What is the function of this protein?
Involved in the synthesis of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells (By similarity).  Pilot protein that is required for the proper localization of the secretin InvG/SctC in the outer membrane (By similarity).  Necessary for efficient adherence and entry of these organisms into cultured epithelial cells (PubMed:8382333).
What are the official names of this protein?
SPI-1 type 3 secretion system pilotin, Invasion lipoprotein invH.
What is the protein family that this protein belongs to?
Belongs to the InvH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: GLMM_LEGPA
Sequence: MSQRKYFGTDGIRGHVGLSNINPEFVLKLGWAVGCVLANGARKKVVIGKDTRVSGYMLESALEAGLSAAGVDVALLGPMPTPGIAYLTQTLRANAGIVISASHNLFEDNGIKFFSADGGKLPDSVELAIEAQLEKQLQTVPSAKLGKATRINDAAGRYIEFCKSTIPSLSRLSNLKIVVDCANGATYHIAPNVFSELGADVVPIGIKPDGFNINQECGSTAPELLREKVIAVGADIGIGLDGDGDRVILVDSLGNLVDGDQIIYIIAKDRHQRGVLHGGVVGTLMSNYGLELAITSLGVPFQRSKVGDRYVLETLREKDWKIGGETSGHIVCLDKTTTGDGIVAALQVLSIMVKQNKALHELTAGIQLLPQTLVNLKTNNAALLASNPDVIQAVKNLEKHLNGEGRVLLRPSGTEPLLRVMVEGANASIVKQQAQMLCDDISQIDKKMTESLPST
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: PETG_HORVU
Sequence: MIEVFLFGIVLGLIPITLAGLFVTAYLQYRRGDQLDL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: TFE_STAMF
Sequence: MYGEKAKKVLLHIIRSGGIVAEETLGKDIGMKSNEARKILQQLADEAILRYKTGRVGDKTLHLWILNIDQIEGILIARLKKTREKLLIRLNYEKNNTFLKCPLCGRRYTFDEAFENDFLCPYDGEQLIEYDNSEEIRILEEKIKEITDELSRIGAA
What is the function of this protein?
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment.  Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal.  It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes.  Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
What are the official names of this protein?
Transcription factor E, TFE, TFIIE subunit alpha homolog, Transcription initiation factor TFIIE.
What is the protein family that this protein belongs to?
Belongs to the TFE family.
Protein: NIFW_AZOCH
Sequence: MTVQPFSPDSDLTLDEAMDELVSAEDFLEFFGVPFDQTVVHVNRLHIMQRYHDYLTKAGDLDEHDDQARYAVVPAAARAYLDFVESDALTEKVFKVFRMHEPQKTFVSIDQLLS
What is the function of this protein?
May protect the nitrogenase Fe-Mo protein from oxidative damage.
What are the official names of this protein?
Nitrogenase-stabilizing/protective protein NifW.
What is the protein family that this protein belongs to?
Belongs to the NifW family.
Protein: CACP_MOUSE
Sequence: MLAFAARTVVKPLGLLKPSSLMKVSGRFKAHQDALPRLPVPPLQQSLDYYLKALQPIVSEEEWAHTKQLVDEFQTSGGVGERLQKGLERRAKKMENWLSEWWLKTAYLQFRQPVVIYSSPGVILPKQDFVDLQGQLRFAAKLIEGVLDFKSMIDNETLPVEFLGGQPLCMNQYYQILSSCRVPGPKQDSVVNFLKSKRPPTHITVVHNYQFFELDVYHSDGTPLTSDQIFVQLEKIWNSSLQSNKEPVGILTSNHRNTWAKAYNNLIKDKVNRESVNSIQKSIFTVCLDKQVPRVSDDVYRNHVAGQMLHGGGSKFNSGNRWFDKTLQFIVAEDGSCGMVYEHAAAEGPPIVALVDHVMEYTKKPELVRSPMVPLPMPKKLRFNITPEIKNDIEKAKQNLSIMIQDLDIMMLTFHHFGKDFPKSEKLSPDAFIQVALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASIDSLAFVKGMGDSTVPEQQKVELLRKAVQAHRAYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFNLSTSQVPAKTDCVMFFGPVVPDGYGICYNPMEAHINFSVSAYNSCAETNAARMAHYLEKALLDMRTLLQNHPRAKL
What is the function of this protein?
Catalyzes the reversible transfer of acyl groups from carnitine to coenzyme A (CoA) and regulates the acyl-CoA/CoA ratio.  Also plays a crucial role in the transport of fatty acids for beta-oxidation.  Responsible for the synthesis of short- and branched-chain acylcarnitines.  Active towards some branched-chain amino acid oxidation pathway (BCAAO) intermediates.  Trans-2-enoyl-CoAs and 2-methylacyl-CoAs are poor substrates.
What are the official names of this protein?
Carnitine O-acetyltransferase, Carnitine acetylase, Carnitine acetyltransferase, CAT, CrAT.
What is the protein family that this protein belongs to?
Belongs to the carnitine/choline acetyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Peroxisome. Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: PROF_VACCC
Sequence: MAEWHKIIEDISKNNKFEDAAIVDYKTTKNVLAAIPNRTFAKINPGEIIPLITNRNILKPLIGQKYCIVYTNSLMDENTYAMELLTGYAPVSPIVIARTHTALIFLMGKPTTSRRDVYRTCRDHATRVRATGN
What is the function of this protein?
Participates in either intracellular transport of viral proteins or intercellular spread of the virus.  Cellular profilins modulate actin filament dynamics (polymerization and depolymerization) via direct binding to actin through an actin-binding domain as well as by modulation of other actin-binding proteins.  In contrast to cellular homologs, the poxvirus profilins seem to bind actin only weakly (By similarity).
What are the official names of this protein?
Profilin.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Localizes to inclusion bodies formed by viral A25/ATI protein in the cytoplasm of the host cell.
Protein: RNH_RIPO1
Sequence: MNDSPKKVLIYTDGACSGNPGSGGYGTVLIYNNHRKELSGGFRLTTNNRMEMMAAIVGLETLTIKCAVTLYTDSRYLVDAITKGWAKKWKANGWKRNAKENAKNPDLWEKLLDLCSQHEVDFVWVKGHAGHQENEYCDRLAVRASQQTNLPSDEVYENKGIET
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSTT_ECOLI
Sequence: MTTQRSPGLFRRLAHGSLVKQILVGLVLGILLAWISKPAAEAVGLLGTLFVGALKAVAPILVLMLVMASIANHQHGQKTNIRPILFLYLLGTFSAALAAVVFSFAFPSTLHLSSSAGDISPPSGIVEVMRGLVMSMVSNPIDALLKGNYIGILVWAIGLGFALRHGNETTKNLVNDMSNAVTFMVKLVIRFAPIGIFGLVSSTLATTGFSTLWGYAQLLVVLVGCMLLVALVVNPLLVWWKIRRNPFPLVLLCLRESGVYAFFTRSSAANIPVNMALCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVNTLGIPVDLPTALLLSVVASLCACGASGVAGGSLLLIPLACNMFGISNDIAMQVVAVGFIIGVLQDSCETALNSSTDVLFTAAACQAEDDRLANSALRN
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARLY_LACP7
Sequence: MKLWGGRFTKETNQLVHNFNASISFDQKFYVQDIRGSIAHVTMLAKQGILNDEEKNKIIDGLNGIRDDIESGSLVIDSTYEDIHSFVEAHLISRIEEIGKKLHTGRSRNDQVALDMKLYTRDEITVLDELLRDLLFELYSLMKEHTETYMPGFTHLQKAQPITLSHHMSAYFEMFRRDRDRLSDIFKRMNTCPLGAGALAGTTYPLDRAYTASLLSFTEPTRNSMDSVSDRDYLIELLSALSTIMMHLSRFSEEIIIWNTNEYRFVEIDDAYSTGSSIMPQKKNPDIAELVRGKTGRVYGALMSLLTTMKGLPLAYNKDMQEDKELTFDAIDTVKGCLSLFTGMIRTMKFNRDTMKASAVLGFTNATDAADYLVNHGVAFRDAHGIIGHLVLTCIEKNCSIEDLSLTELQAISPVFKEDIYDAISLKTCVEKRNTIGGPGVDAMNEVIKECAKYLENNPSIS
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_DINSH
Sequence: MATEEGTGLTFYPMDQFIVSPLFGDGPVHFYTPTNVTLWMALAVAAIALLLVAGTRGRAVVPSRAQSIAELAYGFVYKMVEDVTGKDGIKYFPYIFTLFMFILVANFLGLIPMSFTTTSHIAVTAVLALAVFITVTVIGFVKNGAGFLSLFWVASAPLALRPILAVIEIISYFVRPVSHSIRLAGNMMAGHAVLKVFAGFAQVAAVAPIAIIGVMAIYGLEVLVSAIQAYVFTILTCVYLKDALHPHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y966_RHIEC
Sequence: MSLSTLKNRRERGFFDGQFLIAMPGMEDRNFARTVIYICAHSDAGAMGFVINRPQSLTFTDVLLHLDMIKQEEPIVLPQRARDFPIQTGGPVESGRGFVLHSDDYASDSSIPVSDDICLTATLDIVRAISKGAGPKRATMLLGYSSWAAGQLENEVANNGWLTCPANEELIFDRNLDDKYERALAGMGINAAMLSAEAGHA
What are the official names of this protein?
UPF0301 protein RHE_CH00966.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: CALCB_HORSE
Sequence: MGFGKPSSFLAFSILVLCQAGSLQAQPLRSSLESLPDPAALSEKEGRLLLAALVKAYVQRKTNELEQEQEQEMEGSSLTAQKRSCNTATCVTHRLAGLLSRSGGVVKSNFVPTDVGSEAFGRRRRDLQA
What is the function of this protein?
CGRP induces vasodilation.  It dilates a variety of vessels including the coronary, cerebral and systemic vasculature.  Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role (By similarity).
What are the official names of this protein?
Calcitonin gene-related peptide 2, Beta-type CGRP, Calcitonin gene-related peptide II, CGRP-II.
What is the protein family that this protein belongs to?
Belongs to the calcitonin family.
What are the subcellular locations of this protein?
Secreted.
Protein: UBP1_HUMAN
Sequence: MPGVIPSESNGLSRGSPSKKNRLSLKFFQKKETKRALDFTDSQENEEKASEYRASEIDQVVPAAQSSPINCEKRENLLPFVGLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKGNCKEDSLASYELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLLKKEEVKNVAELPTKVEEIPHPKEEMNGINSIEMDSMRHSEDFKEKLPKGNGKRKSDTEFGNMKKKVKLSKEHQSLEENQRQTRSKRKATSDTLESPPKIIPKYISENESPRPSQKKSRVKINWLKSATKQPSILSKFCSLGKITTNQGVKGQSKENECDPEEDLGKCESDNTTNGCGLESPGNTVTPVNVNEVKPINKGEEQIGFELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKTEMKTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGLEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTNDSYGLFAVVMHSGITISSGHYTASVKVTDLNSLELDKGNFVVDQMCEIGKPEPLNEEEARGVVENYNDEEVSIRVGGNTQPSKVLNKKNVEAIGLLGGQKSKADYELYNKASNPDKVASTAFAENRNSETSDTTGTHESDRNKESSDQTGINISGFENKISYVVQSLKEYEGKWLLFDDSEVKVTEEKDFLNSLSPSTSPTSTPYLLFYKKL
What is the function of this protein?
Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2 (PubMed:15694335).  Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA (PubMed:16531995, PubMed:20147293).  Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity (PubMed:18082604, PubMed:26388029).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 1, Deubiquitinating enzyme 1, hUBP, Ubiquitin thioesterase 1, Ubiquitin-specific-processing protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL18_BRUA4
Sequence: MASPKETLQRRAARVRRQVKAVANGRPRLSVHRSSKNIYVQVIDDVRGVTIAAASTLDGDLKGKLKTGADSAAAAAVGKLVAERAVKAGVSEVVFDRGAFIYHGRVKALAEAAREGGLSF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: HTPX_RHIME
Sequence: MNLMRTAMLLAFMTVLFMAVGYVIGGRGGMMIALVIAAGMNFFSYWNSDRMVLRMYRAQEVDEHSAPEYYGIVRDLAKNAGLPMPRVYVIDSPQPNAFATGRNPENAAVAASTGLLHSLSYEEVAGVMAHELAHIQYRDTLTMTLTATLAGAISMLGNFAFFFGGNRENNNPLGFIGVLIAMIVAPLAAMLVQMAISRTREYSADRRGAEICGNPLWLSSALRKIAGAAQVIHNNDAERNPATAHMFIINPLSGERMDNLFSTHPNTENRVAALERMARETSTGSTAPVRPDNAGRKSRSVPRTGWGRGGSEPPKGPWS
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MUTS2_HELPY
Sequence: MSDAPKRSLNPTLMMNNNNTPPKPLEESLDLKEFIALFKTFFAKERDTIALENDLKQTFTYLNEVDAIGLPTPKSVKESDLIIIKLTKLGTLHLDEIFEIVKRLHYIVVLQNAFKTFTHLKFHERLNAIVLPPFFNDLIALFDDEGKIKQGANATLDALNESLNRLKKESVKIIHHYARSKELAPYLVDTQSHLKHGYECLLLKSGFSGAIKGVVLERSANGYFYLLPESAQKIAQKIAQIGNEIDCCIVEMCQTLSHSLQKHLLFLKFLFKEFDFLDSLQARLNFAKAYNLEFVMPSFTQKKMILENFSHPILKEPKPLNLKFEKSMLAVTGVNAGGKTMLLKSLLSAAFLSKHLIPMKINAHHSIIPYFKEIHAIINDPQNSANNISTFAGRMKQFSALLSKENMLLGVDEIELGTDADEASSLYKTLLEKLLKQNNQIIITTHHKRLSVLMAENKEVELLAALYDEEKERPTYTFLKGVIGKSYAFETALRYGVPHFLIEKAKTFYGEDKEKLNVLIENSSALERELKQKNEHLENALKEQEYLKNAWLLEMEKQKEIFHNKKLELEKSYQQALNILKSEVASKDTSSMHKEIHKASEILSKHKTNQEIPQIITNFQANEKARYKNESVLIVQILDKGYYWIETELGMRLKAHGSLLKKIQKPPKNKFKPPKTTIPKPKEASLRLDLRGQRSEEALDLLDAFLNDALLGGFEEVLICHGKGSGILEKFVKEFLKNHPKVVSFSDAPINLGGSGVKIVKL
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity (Probable).  Also involved in repairing oxidative DNA damage.  Has ATPase activity.  Binds DNA.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: ACP_SYNR3
Sequence: MSQEILEKVRSIVAEQLSVDAAEVKPESNFQNDLGADSLDTVELVMALEEAFDIEIPDEAAEGIATVGDAVSYIQEKKG
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_HAMD5
Sequence: MISKIETETQSRMEKCTESFESQIKKIRTGRASPSILDSIQVEYYGASTPLRQLANIVAEDSSHLAVTVFDRNLTPYIEKAIQNSPLGLNPSSAANLIRVPLPPLTEDRRKELIKVIRSEAEAARVAVRNIRASVNKKSKETLKKKEISEDEDRQIQDNVQKLTDRYIKKIDEFLTKKEKEVMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_RALPJ
Sequence: MNKIRKGDRVIVRTGKDKGKQGTVLAVLAEHVTVEGVNVAKKHVRPNPMLGTTGGVVDKIMPIHISNVALVDANGKPSRVGIKVEGGVKTRVLKTTGAAVGA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: EPMA_HAEIE
Sequence: MTALNHWQPSADIKNLLKRAKIIAEIRQFFTERGLLEVETPVLSEFGVTDLHLSTFSTEFLAPFGEQSKTLWLSTSPEYHMKRLLAAGSGPIFQISKVFRNEEAGNRHNPEFTMLEWYRPHFHMHRLINEVDDLLQQILDCPPAESLSYQFVFQEYVGLDPLSAERSELIEAARKHNFMAEDNEDRDTLLQFLFSEVVEPQIGKERPIAVYHFPSTQAALAQVSPEDQRVAERFEFYYKGLELANGFHELADAQEQRHRFELDNQQRQKCELPTREIDERFLAALEAGMPDASGVALGIDRLMMIALDCEKINDVISFAMDNA
What is the function of this protein?
With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P).  Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.
What are the official names of this protein?
Elongation factor P--(R)-beta-lysine ligase, EF-P--(R)-beta-lysine ligase, EF-P post-translational modification enzyme A, EF-P-lysine lysyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
Protein: PANB_PYRCJ
Sequence: MEKRKVTIRHFLEAKGSRKLAMVTAYDYPTARLVDEAGVDGILVGDSLGMVVLGYENTLRVTLRDMVAHVAAVARARPRALVVADMPFMTYETGPRDALRAAAKLVRAGAEAVKPEGGVEIVDVVEKLTKTGVPVMGHIGLNPQRVLTLGGFRMVGKDEEARRKVLEDAKALQEAGAFALVVEFVPASLAKEVTEAVKIPTICIGAGPHCDGQILVLHDIIGLSEKPPSFAKRYADVASIIREAVAKYVAEVREGKFPTPEHYRP
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_DICTD
Sequence: MFIDRAKIYVKAGDGGNGCIAFRREKFVPKGGPAGGDGGKGGDVIIEADENLDTLLDFHYKRHYYAERGEHGKGKNQKGKDGKDLVIKVPVGTLIFDVETGELLADLVSHGQRVVVAKGGKGGRGNAHFATSTRQTPYFAEKGEKGEERWLYLELKLLADVGLLGLPNAGKSTLLSRISNATPEIAPYPFTTKTPNLGVVEREDITFTVADIPGLIEGAHENKGMGDEFLRHIERTSVLVFVLDAADMVNPPQRAYEILKKELYLYSPKLLEKPRIIAINKIDLPEAQERIPEIEEWLKNEGVPYVFISAKEGINIDKLLELMEKYVKEKKESIPVVEIEKEIEELKQENKKQEIPEIIKEGDLWILKDKKTESLANKLDLYNPQAFSYFLNYAKRRGIIKLINRAKIKDDEEIKIGNYVFKYNSKNNSLELIE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPAST_DROYA
Sequence: MVRTKNQSSSSSASSSSTKSPIKSSSATGSSGGGVGGRQSTHRSSSASNVAAVVAGGSSAAGGGSSSNRRSPGSSPDGDDDTTTTDDLTPTTCSPRSGHHHTYGGYSSSVHKQNLYVVSFPIIFLFNVLRSLIYQLFCIFRYLYGASTKVIYRPHRRDCNIEIVVQNSSKEQQQSLNHPSELNRDSDGQEQQLSNQPQRFRPIQPLEMAANRPGGGYSPGPGDPLLAKQKHHHRRAFEYISKALKIDEENEGHKELAIELYRKGIKELEDGIAVDCWSGRGDVWDRAQRLHDKMQTNLSMARDRLHFLALREQDLQMQRLSLKEKQNEQAPSKPQRTREPMLAGMTNEPMKLRVRSSGYGPKATTGAQPTASGRKLTIGSKRPVNLAVANKSQTLPRNLGSKTSVGAVQRQPAKTAATPPAVRRQFSSGRNTPPQRSRTPINNNGPSGSGASTPVVSVKGVEQKLVQLILDEIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELFTGLRAPAKGLLLFGPPGNGKTLLARAVATECSATFLNISAASLTSKYVGDGEKLVRALFAVARHMQPSIIFIDEVDSLLSERSSSEHEASRRLKTEFLVEFDGLPGNPDGDRIVVLAATNRPQELDEAALRRFTKRVYVSLPDEQTRELLLNRLLQKQGSPLDTEALRRLAKITDGYSGSDLTALAKDAALEPIRELNVEQVKCLDISAMRAITEQDFHSSLKRIRRSVAPQSLNSYEKWSQDYGDITI
What is the function of this protein?
ATP-dependent microtubule severing protein.  Stimulates microtubule minus-end depolymerization and poleward microtubule flux in the mitotic spindle.  Regulates microtubule stability in the neuromuscular junction synapse.  Involved in lipid metabolism by regulating the size and distribution of lipid droplets.  Involved in axon regeneration by regulating microtubule severing.
What are the official names of this protein?
Spastin.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. Spastin subfamily.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton. Chromosome. Lipid droplet. Note=Forms an intramembrane hairpin-like structure in the membrane. Colocalizes with cellular microtubule arrays. Localizes to chromosomes from prometaphase/metaphase to anaphase, and this requires microtubules. Localizes to discrete punctate cytoplasmic foci which may correspond to secretory vesicles.
Protein: MAG_DERFA
Sequence: FVMKREPLRFRDITVEGNENAYIKNGKLHLSLMDPSTLSLVTKADGKIDMTVDLISPVTKRASLKIDSKKYNLFHEGELSASIVNPRLSWHQYTKRDSREYKSDVELSLRSSDIALKITMPDYNSKIHYSRQGDQINMDIDGTLIEGHAQGTIREGKIHIKGRQTDFEIESNYRYEDGKLIIEPVKSENGKLEGVLSRKVPSHLTLETPRVKMNMKYDRYAPVKVFKLDYDGIHFEKHTDIEYEPGVRYKIIGNGKLKDDGRHYSIDVQGIPRKAFNLDADLMDFKLKVSKPEDSNKAQFSYTFNEYTETEEYEFDPHRAYYVNWLSSIRKYIQNFIVEDN
What are the official names of this protein?
Allergen Mag.