PharMolix/UniProtQA huggingface dataset:
Protein: TRI26_HUMAN
Sequence: MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPFKKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLLCVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAALKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVISELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRGLREFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCEPGVLGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETDEDEESLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRLSSSGIWANTSPEAELFPALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFTRRLVPFLWLKWPGTRLLLRP
What is the function of this protein?
E3 ubiquitin-protein ligase which regulates the IFN-beta production and antiviral response downstream of various DNA-encoded pattern-recognition receptors (PRRs).  Promotes nuclear IRF3 ubiquitination and proteasomal degradation.  Bridges together TBK1 and NEMO during the innate response to viral infection leading to the activation of TBK1.
What are the official names of this protein?
Tripartite motif-containing protein 26, Acid finger protein, AFP, RING finger protein 95, Zinc finger protein 173.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Viral infection mediates TRIM26 nuclear translocation.
Protein: PSAD_TRICV
Sequence: MTLNLQTPFPTFGGSTGGWLRAAEVEEKYAITWTSKKEQIFEMPTGGAAIMRNGENLLYLARKEQCLALGTQLRTFKINDYKIYRIFPSGEVQYLHPKDGVFPEKVNPGRTSVNSRGFSIGKNPNPASIKFSGITTYES
What is the function of this protein?
PsaD can form complexes with ferredoxin and ferredoxin-oxidoreductase in photosystem I (PS I) reaction center.
What are the official names of this protein?
Photosystem I reaction center subunit II, Photosystem I 16 kDa polypeptide, PSI-D.
What is the protein family that this protein belongs to?
Belongs to the PsaD family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: UREG_PSEFS
Sequence: MNTQPLRVGIGGPVGSGKTALTLALCLALRDRYNLAVVTNDIYTREDADFLVRNQALAPERIIGVETGGCPHTAIREDASINLEAVDQLNRRFPGLDLILVESGGDNLSATFSPELSDLTIYVIDVSAGDKLPRKGGPGICKSDLLVINKIDLAPLVGASLELMNSDTQRMRNGKPFVFSNQKTGVGLEEIVAFIERQGLLTAA
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMOF_PSEME
Sequence: MFNIQSDDLLHHFEADSNDTLLSAALRAELVFPYECNSGGCGACKIELLEGEVSNLWPDAPGLAARELRKNRFLACQCKPLSDLKIKVINRAEGRASHPPKRFSTRVVSKRFLSDEMFELRLEAEQKVVFSPGQYFMVDVPELGTRAYSAANPVDGNTLTLIVKAVPNGKVSCALANETIETLQLDGPYGLSVLKTADETQSVFIAGGSGIAPMVSMVNTLIAQGYEKPITVFYGSRLEAELEAAETLFGWKENLKLINVSSSVVGNSEKKYPTGYVHEIIPEYMEGLLGAEFYLCGPPQMINSVQKLLMIENKVPFEAIHFDRFF
What is the function of this protein?
Reductase component of the toluene-4-monooxygenase multicomponent enzyme system which catalyzes the O2- and NADH-dependent hydroxylation of toluene to form p-cresol (PubMed:15240250, PubMed:17964805).  Ferredoxin reductase catalyzes the transfer of electrons from NADH to ferredoxin (TmoC) (PubMed:17964805).
What are the official names of this protein?
Toluene-4-monooxygenase system, ferredoxin--NAD(+) reductase component, T4MO, Ferredoxin--NAD(+) reductase, Toluene-4-monooxygenase systme, electron transfer component.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin reductase family.
Protein: XPT_BREBN
Sequence: MKELQERIVQDGKVLSASVLKVDAFLNHQVDPQLTMKIGQRFAELFAGENITKVVTIEASGIHFAMATSFALGVPFIYAKKKKAVTLTEEVYSAPVHSFTRQETYQISVSRQYLSKEDRVLIVDDFLATGAALVGLTNIVKDAGAHLVGVGAVIEKSFQEGRGLLEQAGVRIESLARIESMSPEGIHFIEEEPARV
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTB_BRUME
Sequence: MNLMAERSLENAVGEKMNATASSIKMRGEKVCVFYGEKQALFDVDLDIPEKMVTALIGPSGCGKSTFLRSLNRMNDTIEGCRIAGRITLDNEDIYDPRLDVVELRARVGMVFQKPNPFPKSIYENVAYGPRIHGLARSKAELEEIVVTSLQKASLFEEVKDRLHDAGTGLSGGQQQRLCIARAIAVSPEVILMDEPCSALDPIATAKVEELIDELRQNFTIVIVTHSMQQAARVSQRTAMFHLGNLVEVGDTEMMFTAPTEKRTQDYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PROB_POLSJ
Sequence: MQEKTGSPVLRNARRIVVKVGSSLVTNEGRGLDADAIGLWCEQLAALVKDGREVIMVSSGAIAEGMKRLGWTARPKAIHELQAAAAVGQMGLAQVYESKLRENGIGSAQVLLTHADLADRERYLNARSTLLALLQLGVVPVINENDTVVNDEIKFGDNDTLGALVANLVEADALVILTDQKGLYTADPRKDPAARFVHEAKAGDAALEAMAGGAGSSIGKGGMITKILAAKRAAGSGASTVIAWGREPQALIRLTQGEAIGTLLVAQTQKIQARKQWMADHLQMRGSVAVDAGAVSKVRDEGKSLLPIGMTRVDGDFSRGDVIAIRDAEGAEIARGLANYSSSEARLICRKASSEFERLLGYTGEPEMVHRTNLVLTR
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIA_NEUCR
Sequence: MEAPALEQRQSLHDSSERQQRFTSLILPNGVGCSSREEPQGSGGLLVPHNDNDIDNDLASTRTASPTTTDFSSSSSDDNSTTLETSVNYSHSSNTNTNTSCPPSPITSSSLKPAYPLPPPSTRLTTILPTDLKTPDHLIRDPRLIRLTGSHPFNVEPPLTALFEHGFLTPQNLHYVRNHGPIPSSVATPPATINKEEDDSLLNWEFTVEGLVEHPLKISVRELMDASKWDNVTYPVTLVCAGNRRKEQNVLRKSKGFSWGAGGLSTALWTGVGLSEILARAKPLTKKGGGARYVCFEGADQLPNGTYGTSVKLAWAMDPNKGIMVAHKMNGENLHPDHGRPVRVVVPGQIGGRSVKWLKRIVVTKGPSENWYHVFDNRVLPTTVGPEESGEKTEEMERVWRDERYAIYDLNVNSVICEPGHGEVVSLRGDEGAGTYRLRGYAYAGGGRRVTRLEVTLDQGKSWRLAGIEYPEDRYREAQDGEELFGGRLDVSWRESCFCWCFWDLEIPLSELRKAKDVCIRAMDESLALQPKEMYWSVLGMMNNPWFRVVIHHEGDTLRFEHPTQPMLTSDGWMDRVKKEGGNLANGFWGEKVPGAEENVVKEEPVKEISMVDEKVTRLITLEELRQHDGEEEPWFVVNGQVYNGTPFLEGHPGGAASITGAAGQDVTDEFLAIHSENAKAMMPTYHIGTLTPSAPAALKSSSTSDPALSDPSRPIFLQSKTWNSAILTFKESVSPDTKIFHFALSHPAQSIGLPVGQHLMMRLPDPAKPTESIIRAYTPISDGTLERGTLRVLVKIYYASPTEDIKGGQMTQALDALALGKAVEFKGPVGKFVYQGRGVCSVNGRERKVKRFVMVCGGSGVTPIYQVAEAVAVDDQDGTECLVLDGNRVEGDILMKSELDELVERAKPMGRCRVKYTLSRPGAEWEGLRGRLDKTMLEREVGEGDLRGETMVLLCGPEGMQNMVREVLKGMGWKDEDVLVF
What is the function of this protein?
Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
What are the official names of this protein?
Nitrate reductase [NADPH], NR.
What is the protein family that this protein belongs to?
Belongs to the nitrate reductase family.
Protein: HDAC8_DANRE
Sequence: MSEKSDSNDDKSRTRSVVYVYSPEYIQTCDSLSKVPNRASMVHSLIEAYGLLKYMRVVKPHVASIEEMAVFHTDSYLQHLHKISQDGDNDDPQSADFGLGYDCPVVEGIFDYAAAVGGATLTAAQNLLDGKCDVAINWAGGWHHAKKDEASGSCYVNDAVLGILKLREKYDRVLYVDVDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVTDTGLGKGRWYAVNVPFEDGVRDDRYCQTFTSVMQEVKALFNPEAVVMQLGADTMAGDPMCSFNMTPVGVAKCLTYILGWELPTLLLGGGGYNLANTARCWTYLTGTVLGQTLSSEIPDHEFFTEYGPDYSLEISPSCRPDRNESQHLERVISTIKGNLKNVV
What is the function of this protein?
Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.  Histone deacetylases act via the formation of large multiprotein complexes.  Also involved in the deacetylation of non-histone proteins.  In addition to protein deacetylase activity, also has protein-lysine deacylase activity: acts as a protein decrotonylase by mediating decrotonylation ((2E)-butenoyl) of histones.
What are the official names of this protein?
Histone deacetylase 8, HD8, Protein deacetylase HDAC8, Protein decrotonylase HDAC8.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family. HD type 1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Cytoplasm. Note=Excluded from the nucleoli. Found in the cytoplasm of cells showing smooth muscle differentiation.
Protein: RS10_ACIC1
Sequence: MAGQKIRIRLKAYDHEVIDSSARKIVETVTRTGARVAGPVPLPTEKNVYCVIRSPHKDKDSREHFEMRTHKRLIDIIDPTPRTVDSLMRLDLPAGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RNH_TREPS
Sequence: MNAHAALTLYTDGACLGNPGPGGWAFALVPSDVPFLETGQXAPEAAAFTRSGSAYPSTNNRMELCAVINALQEAHGRAAEAVVVVTDSQYVRKGITQWIHTWKHNGWKTAAKQPVKNKDLWEALSALADALSVEWRWVKGHAGDPYNELCDRLATDAARRAAQSTADCP
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BLVRB_HUMAN
Sequence: MAVKKIAIFGATGQTGLTTLAQAVQAGYEVTVLVRDSSRLPSEGPRPAHVVVGDVLQAADVDKTVAGQDAVIVLLGTRNDLSPTTVMSEGARNIVAAMKAHGVDKVVACTSAFLLWDPTKVPPRLQAVTDDHIRMHKVLRESGLKYVAVMPPHIGDQPLTGAYTVTLDGRGPSRVISKHDLGHFMLRCLTTDEYDGHSTYPSHQYQ
What is the function of this protein?
Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone).  Contributes to heme catabolism and metabolizes linear tetrapyrroles.  Can also reduce the complexed Fe(3+) iron to Fe(2+) in the presence of FMN and NADPH.  In the liver, converts biliverdin to bilirubin.
What are the official names of this protein?
Flavin reductase (NADPH), FR, Biliverdin reductase B, BVR-B, Biliverdin-IX beta-reductase, Green heme-binding protein, GHBP, NADPH-dependent diaphorase, NADPH-flavin reductase, FLR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KERA_CHICK
Sequence: MMTLKVCPSLLLLFLVHSVWTRTVRQVYNELDPEHWSHYTFECPQECFCPPSFPNALYCDNKGLKEIPAIPARIWYLYLQNNLIETISEKPFVNATHLRWINLNKNKITNNGIESGVLSKLKRLLYLFLEDNELEEVPAPLPVGLEQLRLARNKISRIPEGVFSNLENLTMLDLHQNNLLDSALQSDTFQGLNSLMQLNIAKNSLKKMPLSIPANTLQLFLDNNSIEVIPENYFSAIPKVTFLRLNYNKLSDDGIPPNGFNVSSILDLQLSHNQLTKIPPINAHLEHLHLDHNRIKSVNGTQICPVSIAVAEDYGLYGNIPRLRYLRLDGNEIQPPIPLDIMICFQLLQAVVI
What is the function of this protein?
Plays an important role in generating and maintaining a transparent matrix within the corneal stroma.
What are the official names of this protein?
Keratocan, KTN, Keratan sulfate proteoglycan keratocan.
What is the protein family that this protein belongs to?
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RS16_SHEB9
Sequence: MVTIRLARGGAKKRPFYNIVVADSRNARDGRFIERVGFFNPLARGQEETLRLDLARVEHWVSNGAAATERVAKLIKDARKATA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: GUF1_LEIBR
Sequence: MKRHGVCNTSGVALTRYSERLRFRTTHYGNGNMATSHQSCCGRRLDFYTGPGKGWCFTSLLPVLRRYCSASSSSTTAVAPVQAHGEDLYVSHYAIPEDAHRLVGTPQLLPRSPAEEVAFKKSLIKSFPQACIRNVSVVAHVDHGKTTLADAMLRFSNLLPADGATGTFTDRLQVEKERGITIKAQTCSVLLTLRETGTQYLVNLIDTPGHVDFQYEVSRSLRASEGAALLVDVRQGVEAQTMAQFYAALEQNLTILPVLTKMDSVMNDAEVEKTLLQLEDSTGLLSREAVLTSAKSKQGIEQLFQHIIDKVPPPRGRAGFSDMKQLPIMHADSAERKQMEKELVPLRALLFDCWTAESSGMTDGAASAPASAATSFSSVSSGTVTASGGQPVAREGIYGLIRVMDGTVTPGTMVTFCHSGKKHEVREVGIIHPTLHPTAALTAGMVGFVFFPGLTKRDVFIGDTLCTLPTRKHTVRVGVSNIPAAELGTEPTATAELASSDSFAVEPIPGFKTVHPVVFAGFYPDEGVYITQLRDAVDLLCVNDPSVTMEQLQCPTLGPGLQLGFLGFLHMQVFKERLLMEFGQTVLVTPPQVQYMYVEQHCDPGDPAQRKPVSVSNWRWPHEGVGAYLEPFVTATVLTPTQYFSEINSAALSSFRGEMQEMRVIDDARTLVRYRMPLADLARGFFSTVKSSSHGYATLEYDDLTYMAADLVKMDIVINKARISALSTICLRHEANTHARRIICSLKENLLRSSVDLPLQALVGSKIITRETVKAYRKDVTAKIHAGDISRKQKKWNDQKKGKERMARRSVGTVTLDQSVLAAAMGATTAR
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1 homolog, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1 homolog, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: GLMM_RHOP2
Sequence: MSRRYFGTDGIRGRANGLITPELALKVGQAAGLVFQRGDHRHRVVIGKDTRLSGYMIENAMVAGFTSVGMDVLLVGPMPTPAVAMLTKSMRADLGVMISASHNMFEDNGIKLFGPLGFKLSDDVEKQIEQLLDEPMDKKLSESASLGRARRIDGVHDRYIEFAKRTLPRDLSLDGLRVVVDCANGAAYKVVPEALWELGADVISIGVEPDGFNINKECGSTSPEALCRKVREMRADIGIALDGDADRVIMVDERGHVIDGDQLLAVIAQSWKEDGRLARPGIVATVMSNLGLERFLASEGIELVRTSVGDRYVLEAMLRDGYNVGGEASGHIILSDYATTGDGFVAALQILAVVQKLGRPVSEVCHRFDPLPQILKNVRYRAGRPLDDAGVQSAISDAEKRLNGHGRLLIRPSGTEPVIRVMGEGEDRIMVEEVVDTIVDALGNASAAAA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: LSM6_DEBHA
Sequence: MSSIKKESSSGSENTGPSVFLSEIIGSSVTVRLHNGVEYLGNLQSIDGYMNIVLDETKEFVGGDQARNYGDVFIRGNNVLYISEA
What is the function of this protein?
Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates.  Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway.  Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs.  LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6. U5 tri-snRNP, and free U6 snRNP).  It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes.  LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA (By similarity).
What are the official names of this protein?
U6 snRNA-associated Sm-like protein LSm6.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: THYX_AQUAE
Sequence: MMKIYLMGSDQRIVRCARVSFAKDSYVDEKRDKRLIRYLFKHRHASPFEHNIIAFEWKKEKWIELLSKLENPTVQVYYSNGFVFLNLRNAINVWELLPDAVKERIKEAFPTTYGVIQRRGEIEDEELYSLPYTKDKAYVKEKIETSSGWIGLVDKLELETDMDFYTFVVECPLFVARQWMRHRFGSYNEVSKRYVGKEFLEFYLPKYIRKQAEKNKQASVDEPISESEVFIKKIENLISKSVKLYEEIIEKGGAKELARGVLPQFMKTRFYWTVPRISLDNFITLRTHEGAQKEIREFAEAIKEMVGYRGTDKKNVI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase ThyX, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.
Protein: ENV_WDSV
Sequence: MDTPGSLQVIAIISLLLVGGASQPATFLEKALPTDGPSLETIEHKTEMVNTTRSEEQSPVRPSKTRQQLIDETPEICANAWVIRLITEFPTELGNMSQKQKTIAIQVHNTTMTMEETVFSLVSHVNKKNYEIHNVSGICTKYQLVPGNFTCSTRKCISQTKEKRIISTTVKDTYEVYLPFAWSQKPTGGDKYPEPQIGYNTGTGRLNQWNKDEFVIKQCRKKRGKRQITVPNSTLSPTGTTDFTKFTPNPISPNSTALNELEQKTTPIGTEQPFNNEKWQNLIFGNIVTKMDPQCEAELFQQFNISDKTVQVEFKVTSLPGQNISCQAIYNTEHGINIENKNCVISLIKENRKIKAHAYITRTGSYEWYAQQVTSKGIIQEVRNLVTIVECECPIVKPLPQGGIIPLTMPMRVLTNPSPILIHSALKFDLSKFGLSPCSFSPMEWQTYITKPLKRAMHGFEVHQRKKRDLGIGLHSTLNSWWNGANSLGLTVESADRQKYDQKILKVLQNLAVQQRTDVKNQQTLGKALETPIYTITLQLADSLTAAILKHEQQQNVGITCKDIAILTVTQIATYLRDIQHEHLPVWFIEQITNQILLPVGQVIMPEITAPPILNPLIGWNQSVLVIGLTHQLTITTVQQPLYKAANMGNFQDWTPFPPFILANKTHGFSIDCPIMRNSFLCHTLPTPVKLSEWERSTSTIYQTSPQVWITPEGKACLNHRNITVQDRTCLINKPGCFIPKHPWSAGKQTIVPTQYIQQNFVPDTIDTEDNQTRVLQKEMIEAISKAKRDYGVLKQGQIALIRHHEAITTILGQEATYSIKETQALISSIEQEAWYNNLFSWYDGSVWSQLQLIIVVITCTIPLLWVLNTCLFFKLRRAIRRERDNNIVVEYQAQTRGRRTHMTEPITKKQRAKLLRHAKTNRRLPRSLRATPAVSAFEMVTFDPQEETVEINRIDPSHENNDHGGPMNMAPIISADSYALPTPYITIMLDRELLNQGMRKVITLLNDPAREVFNKAYNLVTTNHFTLAYGCDESAGWVNQHAEYMGKPVIVTLAGLVITPVGLAWIPLPQQEPLEKLFMVPNSMPHVTVAMADYHETKEMGKIVKDINNEELLLVKPQLFKWGPEGFFVACPLVIRGVVTGHSLLHIACPATAVQAEGT
What is the function of this protein?
(TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm (By similarity).
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Multi-pass membrane protein. Host cell membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. Both proteins are thought to be concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag (By similarity).
Protein: PALD_CHICK
Sequence: MGTTASTAQQTVSASAFESVHGIGTMEDQRSLSIHSFQTLGLHNSKAKSIITNKVAPVVITYNCREEFQIHDDLLKANYTVGRISDATLEHYLVQGKYFMVRDVYSKLDVLNTTASCGAPNFRQAKGGYAVFGMGQPSLGGFKLVLQKLQREGHKECVFFCVREEPVLFLRVESDFVPYTPRGKENLHENLHSLRRGLRVEDLELTIRKEIHDFAQLSEGVYYVYNDIERFRDEPHTVRVQGEEDIHVTEEVYRRPIFLLPTYRYHRLPLPVDGAPLEEQFDAFICFLRESSGLLLRDPSRPPPALLFSCQTGVGRTNLAMALGTLILHHHRGAAPKPDPPHPAKMPPRARFRVIQSFIEMVPKGQQMVEEVDSVIASCSEMHDMKEAIYESKKKLEGIGEDYQIQGNSTKEYFLQRTLQSLERYFYLIAFNYYLHEQYPLGFALSFSRWMCRHPELYRLQAIMNSSELTITGDLITKGTRVLVVDERFCPDVLSTVKEMSVANFRRVPKMPIYGTAQPSSKALGSVLRYLTDAKRKHSRILWVSLREEVVLEGNEQIYTLREPGSLDQLIPVPVSTPEQLEKLESTLKGDLLKSQKWLEVYLEAEKQMKMFKSCLTTQEIFNQHKSTCQGLTYRRIPIPDFCAPKEQDFDRLLEAMKSALAEDSQTAFVFNCASGRGRTTTAMVIAVLTLWHFNGIPEMSEEEIVSVPDAKYTKGEFEVVMKVVQLLPDGHRMKKEVDMALDTVSETMTPMHYHLREIIICTYRQGRSGKDEQERRLLRLRSLQYLERYIYLILFNSYLHLEKKDSWQRPFSLWMREVAAVAGVYEVLDGLGFPELEQLEDEEPLRKLRGRWRAQSGAGWPSRGDLV
What are the official names of this protein?
Paladin.
What is the protein family that this protein belongs to?
Belongs to the paladin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: CLPX_ECO24
Sequence: MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVISHRVETGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDESVIDGQSKPLLIYGKPEAQQASGE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: RL17_DEIGD
Sequence: MRHGKAGRKLNRNSSARVALARAQATALLREGRIQTTLTKAKELRPYVEKLITTAKGGDLHARRLIARDIHDKDVVRKVMNEVAPRYAERQGGYTRILRVGTRRGDGVTMALIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: YVBD_VACCC
Sequence: MNSIPVPTLTETSRSFIIIPLSVSITHCLTRDSFGIVRTISSNGITAHLVNSLYILCNMALLLPYTINLLL
What are the official names of this protein?
Uncharacterized 7.8 kDa protein.
Protein: GLGC_BACSU
Sequence: MKKQCVAMLLAGGKGSRLSGLTKNMAKPAVSFGGKYRIIDFTLSNCSNSGIDTVGILTQYQPLELNSYIGIGSAWDLDRYNGGVTVLPPYAESSEVKWYKGTASSIYENLNYLNQYDPEYVLILSGDHIYKMDYGKMLDYHIEKKADVTISVIEVGWEEASRFGIMKANPDGTITHFDEKPKFPKSNLASMGIYIFNWPLLKQYLEMDDQNPYSSHDFGKDIIPLLLEEKKKLSAYPFKGYWKDVGTVQSLWEANMDLLKEDSELKLFERKWKIYSVNPNQPPQFISSDAQVQDSLVNEGCVVYGNVSHSVLFQGVTVGKHTTVTSSVIMPDVTIGEHVVIENAIVPNGMVLPDGAVIRSEKDIEEVLLVSEEFVEKELI
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.