PharMolix/UniProtQA huggingface dataset:
Protein: Y1634_ARATH
Sequence: MRSKYFCSLALVLGLFFVSCDGFASNEVQALRRFKEAIYEDPLLVMSNWNDPNSDPCDWTGIYCSPSKDHVIKINISASSIKGFLAPELGQITYLQELILHGNILIGTIPKEIGNLKNLKILDLGNNHLMGPIPAEIGSLSGIMIINLQSNGLTGKLPAELGNLKYLRELHIDRNRLQGSLLVAGASGYQSKVYSSNSSANIAGLCKSLKVADFSYNFFVGNIPKCLENLPRTSFQGNCMQNKDLKHRSSSQCANAQLVKTHGSPSAAPKHQSAQMVAKHHRASKPKWLLALEIVTGSMVGLLLLVALFSAVHRWNNRSTLIIPWKKSSSEKEKFTVYVDSEMLKDVSRLTRQELEVACEDFSNIIGLSADSQIYKGTLKGGSEIAVISLCVKEEDWTGYLELYFQREVADLARLNHENTAKLLGYCKEISPFTRMLVFEYASNGTLYEHLHYGEAALVSWARRMKIVIGIARGLKYLHMELDPPFTISELSSNAIYLTEDFTPKLVDFECWKTILARSEKNLRNISSQGSICVLPNGMESRYLDVSGNIYAFGILLLEIVSGRPPYCKDKGFLIEWAKEFLEAPEAMSGLVDPELKHFNQEDLETVCEVASQCLNRDPTNNNNNHNKPSVQELCETLESRISLSISAELRSSSLAWAELALDS
What are the official names of this protein?
Probable LRR receptor-like serine/threonine-protein kinase At1g63430.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: YIU0_YEAST
Sequence: MTFFLKRKISFFLSGIAQTFLFLPILLNRSVIHVVFLTVVLGHRIPWDSVIRCNNTGTTHSAVSSRTELLLPIGGVINNWKRRAWNGFSIQWIWRYSFVY
What are the official names of this protein?
Uncharacterized protein YIR020C.
Protein: PLSY_STRP1
Sequence: MKLLLFITIAYLLGSIPTGLWIGQYFYHINLREHGSGNTGTTNTFRILGVKAGTATLAIDMFKGTLSILLPIIFGMTSISSIAIGFFAVLGHTFPIFANFKGGKAVATSAGVLLGFAPLYLFFLASIFVLVLYLFSMISLASVVSAIVGVLSVLTFPAIHFLLPNYDYFLTFIVILLAFIIIIRHKDNISRIKHHTENLIPWGLNLSKQVPKK
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IF1_CHLAB
Sequence: MAKKEDTIVLEGRVKELLPGMHFKILLENGMPVTAHLCGKMRMSNIRLLVGDRVTVEMSAYDLTKARVVYRHR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_LEPBJ
Sequence: MKFNFITLFPEKIQSYFSEGLQQKAIESGIFSINTIQLRDFSGNKHNRVDDTIYGGGPGMLLRVEPIHKALLSLGENKGIVILTSPSGIPFHQGIANKLKETGKPLTFISGYYEGVDHRVAEHLVDMEMSLGNYVISAGDLASICIADAVSRLLPGFLGAGESLLDESHNYPDVLEYPQFTKPSEYNGWKVPEVLLSGNHASILAWREQNRKKIDPDQERKL
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_PROM9
Sequence: MTKLSRKLQTQKRHRRLRRSVIGDATRPRLSVFRSNNHIYAQVIDDSAQKTICSASTVDKELREKSDKLPSDCNSSSIVGKLLANRAIKKGIKQVIFDRGGNLYHGRVKALADAAREAGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: GUAAA_METMJ
Sequence: MLPLYVVNNHGQFNHLILRTLRDMDIEATMISNETPPAEVARGCRGIVLGGGPTLERAGVASAYLDLGLPVLGICLGLHIMATARGGAIRRGASGGFGAVEVEIFEQNPLLRGYPDRMQVWASHADEVSVVPEGFVRLAGSSICGVEAMASPDEHLYGIQWHPEVSHTVNGRLLFENFDGICSE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing] subunit A, Glutamine amidotransferase.
Protein: HUTI_SHEFN
Sequence: MSWDQVWIDVNVATMDTNIQGAYGVIPQAAIAVKDGKIAWVGPRSELPEFDVLATPVYRGKGGWITPGLIDAHTHLVFAGNRANEFEQRLQGATYAEIARAGGGIISTVNACRDADEAELFELGRQRLNALAREGVTTVEIKSGYGLNTETELKLLRVARELGEHHHIDVSTTFLGAHAIPPEYKDNADAYIDLVVNDMLPAVIAENLADAVDVFCENIAFNLEQTERVLTAAKQAGLQIKLHAEQLTNMGGSALAAKLGAKSVDHIEFLDEAGIKAISESGTCATLLPGAFYFLRETQLPPIDLLRQYKVPMVIASDFNPGSSPICSTLLMLNMACTLFRLTPEEALQGVTINAAKALGIDNNVGSITVGKQADFCLWDITTPAQLAYAYGVNLCKTVVKNGQVVALPN
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_MOOTA
Sequence: MAIKKFKPTSPGRRQMTVSTFAEITATEPYKPLVEPLKKTGGRNNQGRLTVRHRGGGHKRLYRVIDFKRDKDGIPGRVATIEYDPNRSANIALINYADGEKRYILAPENLQVGDQVISGPEADIKVGNALPLSQIPVGTMVHNVELKPGKGGQMARSAGAGAQLMAKEGGYALLRLPSGEVRKVQESCRATVGQVGNLDWENINIGKAGRKRWLGIRPTVRGVVMNPVDHPHGGGEGRAPVGRKHPVTPWGKPAMGAKTRKKRKLSDKLIVKPRNK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RNPC3_MOUSE
Sequence: MAGPEPPMPLSRGGPGSASLSPPRGDRTLLVRHLPAELTAEEKEDLLKYFGAQSVRVLSDKGRLKHTAFATFPNEKAAIKALTRLHQLKLLGHTLVVEFAKEQDRVHSPCSTSNTEKKKRLDDTVENDKEKKEPDILTVENGIAPNHGLTFPLNSCLKYMYPPPSSTILANIVNALASVPKFYVQVLHLMNKMNLPTPFGPITARPPMYEDYMPLHAPLPPTSPQPPEEPPLPDEDEDLSSKESEYESSDEEDRQRMNRLMELANLQPKRPKTEKPRHVRKKRKIKDMLNIPSSASHSLHPVLLPSDVFDQPQSVGNKKIEFNISTNMPAAFNKDLETQPNNEEENSDSPDTGLDSNTGFGKIFPKPNLNITEEITEDSDEIPSQFISRKELEKGRISREEMETLSVFRSYEPGEPNCRIYVKNLARHVQEKDLKFIFGRYVDFSSETQRIMFDIRLMKEGRMKGQAFVGLPNEKAAAKALKEANGYVLFGKPMVVQFARSARPKQDSKEGKRK
What is the function of this protein?
Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns.  U12-type introns comprises less than 1% of all non-coding sequences.  Binds to the 3'-stem-loop of m(7)G-capped U12 snRNA (By similarity).
What are the official names of this protein?
RNA-binding region-containing protein 3, RNA-binding motif protein 40, RNA-binding protein 40.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACPS_ESCF3
Sequence: MAILGLGTDIVEIARIESVIARSGERLARRVLSDNEWEIWKTHHQPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVFNDELGKPRLRLWGEALKLAEKLGVVNMHVTLADERHYACATVIIES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_NAJAN
Sequence: MSNQHTLLMSNLLPVGSNISTWWNFGSMLLTCLMLQITTGFFLAIHYTANINLAFSSVIHITRDVPYGWIMQNLHAISASMFFICIYIHIARGLYYGLYLNKEVWLSGTALLITLMATAFFGYVLPWGQMSFWAATVITNLLTAIPYLGTMLTTWLWGGFSINDPTLTRFFALHFILPFAIMALSSIHIILLHNEGSNNPLGTNSDIDKIPFHPYHSYKDMLMFTSMITLLFITLSFSPDLLNYPENFSKANPLVTPQHIKPEWYFLFAYGILRSIPNKLGGALALLMSVMILTTVPFTHTSYTRSMMFRPLSQILFWTLMATFITITWTASKPVEPPFISISQTTSIFYFSFFITIPLLGWTENKIMMMNN
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ILVC_MYCBO
Sequence: MFYDDDADLSIIQGRKVGVIGYGSQGHAHSLSLRDSGVQVRVGLKQGSRSRPKVEEQGLDVDTPAEVAKWADVVMVLAPDTAQAEIFAGDIEPNLKPGDALFFGHGLNVHFGLIKPPADVAVAMVAPKGPGHLVRRQFVDGKGVPCLVAVEQDPRGDGLALALSYAKAIGGTRAGVIKTTFKDETETDLFGEQTVLCGGTEELVKAGFEVMVEAGYPAELAYFEVLHELKLIVDLMYEGGLARMYYSVSDTAEFGGYLSGPRVIDAGTKERMRDILREIQDGSFVHKLVADVEGGNKQLEELRRQNAEHPIEVVGKKLRDLMSWVDRPITETA
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: YIDD_CHRVO
Sequence: MSRILILLIRFYQLAISPWLAPRCRFQPTCSGYAIEAVSKHGALKGGCLAARRICRCHPWGGSGYDPVP
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ATPG_SHEFN
Sequence: MASAKEIKTKIASVKNTQKITSAMEMVAASKMRRAQERMAASRPYAENMRKVIGHVAQGTLEYKHPYLEVRDAKRVGYIVVATDRGLCGGLNVNLFKKVVSDVKKWKEQGADVEFCPIGARSVQFFKSFGGEVSAHASGLGDAPKLADLIGTVRVMLKAYNEGKLDRLYIVFNKFVNTMTQTPVIEQLLPLPKSDEEVASYPWDYIYEPDPKEVLDLLLTRYVESQVYQGVVENIASEQAARMVAMKAATDNAGEMIDDLQLVYNKARQAAITQELSEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DTD_AROAE
Sequence: MLALVQRVCEARVVVEGEVVGRIGRGLLVFLCAERGDTEAEGERLLVKLLKLRIFADAQGRMNRSVQDVGGGLLIVSQFTLAADASGGNRPSFSGAAAPADGLRLYEVFVRGARALHPEVESGQFGADMQVHLVNDGPVTVPLRIVPTALPV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMP2_SCOMU
Sequence: GILKKFMLHRGTKVYKMRTLSKRSH
What is the function of this protein?
Antimicrobial peptide against both Gram-positive, -negative and yeast.  Also induces histamine release by mast cells and shows moderate hemolytic activities against both human and rabbit red cells.
What are the official names of this protein?
Antimicrobial peptide scolopin-2.
What are the subcellular locations of this protein?
Secreted.
Protein: CRNF_LYMST
Sequence: MLLKLIVALSLTLTLASATSDPKGWFCSFECNDWNQLEMACQKEKDCFEKTNNQFTNETVACMQPCWDLGIPCRTQCYKVYDQCTSDCPYTVPNPYECFTTCFKEAFAEVKPQIPKANLDE
What is the function of this protein?
Interacts with the p75 low-affinity neurotrophin receptor.  Evokes neurite outgrowth and modulated calcium currents in pedal motor neurons.  May be involved in target-derived trophic support for motor neurons.
What are the official names of this protein?
Cysteine-rich neurotrophic factor, CRNF.
What are the subcellular locations of this protein?
Secreted.
Protein: ACSA_XANOM
Sequence: MADVYPVDPAFAADARVTREQYAALYRESIEHPEQFWGKAAQRLEWFKQPTQVKDVSYALDDFHIRWFGDGELNASVNCLDRQLATRGDKTALLFEPDSPDAASYPVTYRQLYERVCKLGNALRNLGVKKGDRVTIYLPMIVDAAVAMLACARIGAVHSVVFGGFAANSIADRVIDCQSKLIITADEGLRGGKKIPLKANVDAALKIPGTNTIETVLVVRHTGGAVEMQAPRDRWFHDVVDGQPAECEPERMNAEDPLFILYTSGSTGKPKGVLHTTAGYLLFASYTHEVVFDLREDDIYWCTADVGWVTGHSYIVYGPLANGATAVMFEGVPNYPNVSRFWEVIDKHQVTIFYTAPTAIRALMRDGAEPVKKTSRKSLRLLGSVGEPINPEAWRWYYDVVGDSRCPIVDTWWQTETGGILISPLAGAVDLKPGSATLPFFGVQPALVDAEGKILEGATEGNLVLLDSWPGQMRSVYGDHQRFIDTYFRTYPGSYFTGDGCRRDADGYYWITGRVDDVINVSGHRIGTAEVESALVSHPKVAEAAVVGFPHDVKGQGIYAYVTLIAGETPSDELHKELVSWVRKEIGPIASPDHLQWAPGLPKTRSGKIMRRILRKIAENAPDQLGDTSTLADPSVVDSLVNERLTR
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: TYPH_MYCTU
Sequence: MTDFAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVESLPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGTAMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVRPLIVDRIV
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: BTUR_ECOLI
Sequence: MSDERYQQRQQRVKEKVDARVAQAQDERGIIIVFTGNGKGKTTAAFGTATRAVGHGKKVGVVQFIKGTWPNGERNLLEPHGVEFQVMATGFTWDTQNRESDTAACREVWQHAKRMLADSSLDMVLLDELTYMVAYDYLPLEEVVQALNERPHQQTVIITGRGCHRDILELADTVSELRPVKHAFDAGVKAQIGIDY
What is the function of this protein?
Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids.  Participates in the adenosylation of a variety of incomplete and complete corrinoids (By similarity).
What are the official names of this protein?
Corrinoid adenosyltransferase, Cob(II)alamin adenosyltransferase, Cob(II)yrinic acid a,c-diamide adenosyltransferase, Cobinamide/cobalamin adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Cob(I)alamin adenosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDE6_DROME
Sequence: MTDVSSPAGGAASPVEMSTTSSSSAATTSASSSKPLTNGANKTAISTAAGGVTPGAVPGPGSGAIPASSSSGNQVKLEHHHRQSNNNRPAVTNRSSETKLMTPTGSSSSPSQSPSQTQASIQTQTSQQDRLAKASTTASQQDVDEVARLFEEKPEAFEKWLTERAPPEALSRLQEFIENRKPHKRPSVTSDLFQQWMAASPTVQQKSPRSLSNSSASSLPECRRHLMDLDEGELFMELIRDVANELDIDVLCHKILVNVGLLTHADRGSLFLAKGTPTNKYLVAKLFDVTQKTALKDAVTRASAEEIIIPFGIGIAGMVAQTKQMINIKEAYKDARFNCEIDLKTGYKTNAILCMPICNYEGDIIGVAQIINKTNGCMEFDEHDVEIFRRYLTFCGIGIQNAQLFEMSVQEYRRNQILLNLARSIFEEQNNLECLVTKIMTEARELLKCERCSVFLVDLDCCEASHLEKIIEKPNQPATRAIKSADSFEEKKMRNRFTVLFELGGEYQAANVSRPSVSELSSSTLAQIAQFVATTGQTVNICDVIEWVRDHNQIRAEDEIDSTQAILCMPIMNAQKKVIGVAQLINKANGVPFTDSDASIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASQDQTEKLTQDVIAEAESYNLYSFTFTDFELVDDDTCRAVLRMFMQCNLVSQFQIPYDVLCRWVLSVRKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMTDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYTTSTMEHHHFDQCVMILNSEGNNIFQALSPEDYRSVMKTVESAILSTDLAMYFKKRNAFLELVENGEFDWQGEEKKDLLCGMMMTACDVSAIAKPWEVQHKVAKLVADEFFDQGDLEKLQLNTQPVAMMDRERKDELPKMQVGFIDVICLPLYRVLCDTFPWITPLYEGTLENRRNWQDLAEKVEMGLTWIDHDTIDKPVEEFAACADEEIKDIEFTVTTLNCNQQSQHGSEDSHTPEHQRSGSRLSMKKTGALGKAVRSKLSKTLYNSMDGSKPKTSLKLLESHVSEDMDDKSPTSPSQPQASGSMGRMSASSSTSSAGGQMVDKSKKRSKLCALL
What is the function of this protein?
Hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes (PubMed:15673286).  Has cAMP phosphodiesterase activity in vitro but not in vivo (PubMed:15673286).  Has a role regulating cGMP transport in Malpighian tubule principal cells (PubMed:16232123).
What are the official names of this protein?
cGMP-specific 3',5'-cyclic phosphodiesterase, DmPDE5/6, DmPDE6.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Note=Expressed on the apical side of the Malpighian tubule principal cell polarized membrane. Loss of prenylation causes protein location to the cytoplasm.
Protein: KEFB_YERPP
Sequence: MEGTGLLTAVLVFLFAAVVAVPIAQRLGIGAVLGYLIAGIAIGPWGLGFIRDVDEILHFSELGVVFLMFIIGLELNPAKLWQLRRSIFGVGAGQVVITAAVLGALLYFTQFAWQAAVIGGVGLAMSSTAMALQLMREKGMNRNEGGQLGFSVLLFQDMAVIPALALIPILAGNEGGANDWVKIGLKIAAFAGMLIGGRYLLRPLFRYIVASGVREVFTAAALLVVLGSALFMDALGLSMALGTFIAGILLAESEFQHELEIAIEPFKGLLLGLFFISVGMALDLGVLFTHLLDVLLGVLALVFIKSAILYGLARVFGLRRSVRLQFAGVLSQGGEFAFVLFSAAFSQRVLNAEQLALLLVVVTLSMMTTPLLMQVIDRILVRRYNAQEESDEKPFVEDNDPQVIIVGFGRFGQVIGRLLMANKMRITVLERDVSAVSMMRKYGYKVYYGDATELELLRAAGAEKAKAIVITCNEPEDTMALVHLCQQHFPNLHILARARGRVEAHELLQNGVKDFTRETFSSALELGRKTLLELGMHPHQAYRAQQHFRRLDMRMLRELMPQHHGDVAQISRIKEARRELEDIFQREMLHESRQLDGWDEYE
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefB, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL3_DESVV
Sequence: MAEKMGILGRKIGVTRIFASDGSAVAVTVIKAGPCPVTQVKTVATDGYDAIQIAFDEAKEKHLNKPEIGHLAKAGKGLFRTLREIRLEAPAAYEVGSELDVTLFATGDRVKVSGTSIGKGYQGVMRRWNFAGSKDTHGCEKVHRSGGSIGNNTFPGHVFKGKKMAGHWGNESVTVLNLEVVDVRPEDNVILVKGSVPGPKNGLVMVRKQ
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: ATPE_CAMJR
Sequence: MNDLINFEIVTPLGVIYQGEVKSVTLPGSEGEFGVLKGHAALVSSLKSGVIDIEKADLNHELIAIDAGHAKVDEDKICVLAKGAVWVCGSDESEIEKNLAQAKDLIKSMSSDNAALAATFSKLDNARMH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RPOB_PROM2
Sequence: MSSSALQVAKTATYLPDLVEVQRASFKWFLEQGLIEELQNFSPISDYTGKLELHFIGEEYRLKRPRHDVEEAKRRDATFASQMYVTCRLINKETGEIKEQEVFIGELPLMTERGTFIINGAERVIVNQIVRSPGVYFKDELDKNGRRTYNASVIPNRGAWLKFETDKNNLLYVRVDKTRKINAHVLMRAMGLSDNDVVDKLRHPEFYQSSIESANDEGINSEDQALLELYKKLRPGEPPSVSGGQQLLHSRFFDPKRYDLGRVGRYKINKKLRLTVPDDVRTLTHEDVLSTIDYLINLELDIGGASLDDIDHLGNRRVRSVGELLQNQVRVGLNRLERIIKERMTVGETDSLTPAQLVNPKPLVAAIKEFFGSSQLSQFMDQTNPLAELTHKRRISALGPGGLTRERAGFAVRDIHPSHYGRLCPIETPEGPNAGLINSLATHARVNEYGFIETPFWEVNNGKVDKEGNPVYLSADLEDECRVAPGDVATDKEGNIIANLIPVRYRQDFEKVPPHQVDYVQLSPVQVISVATSLIPFLEHDDANRALMGSNMQRQAVPLLRPERPLVGTGLESQVARDSGMVPITKVNGIVSYVDANEIVVKDDHGNEHFHYLQKYQRSNQDTCLNQRPIVKIGDRVISGQVLADGSACEGGEIALGQNVLIAYMPWEGYNYEDAILVSERMVTDDLYTSVHIEKYEIEARQTKLGPEEITREIPNISEESLNNLDEMGIIRIGAFVESGDILVGKVTPKGESDQPPEEKLLRAIFGEKARDVRDNSLRVPKTEKGRVLDVRIYTREQGDELPPGANMVVRVYVAQRRKIQVGDKMAGRHGNKGIISRILPREDMPYLPDGTPVDIVLNPLGVPSRMNVGQVFELLMGWAASNLNCRVKVVPFDEMYGAEKSHQTVQAFLEEASKQPGKAWVYNPDDPGKLLLKDGRTGEPFDQPVAVGYSHFLKLVHLVDDKIHARSTGPYSLVTQQPLGGKAQQGGQRLGEMEVWALEAYGAAYTLQELLTVKSDDMQGRNEALNAIVKGKPIPRPGTPESFKVLMRELQSLGLDIGVYTDEGKEVDLMQDINPRRNTPSRPTYESLGTSEYEED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: RNH_COXBU
Sequence: MAKQEQNIVYLYCDGACRGNPGPGGWGVLLRYNQHERQLHGGVANTTNNQMELTAAIEGLKSLKKPCQVVVTTDSQYLRRGITEWLPVWKRRGWRTSNKKPVKNQPLWETLEREVERHTIVWHWVKGHSGHAENEIADELANRGIDEVLKRGVQ
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_STAA8
Sequence: MTLAQVEYRGTGRRKNSVARVRLVPGEGNITVNNRDVREYLPFESLILDLNQPFDVTETKGNYDVLVNVHGGGFTGQAQAIRHGIARALLEADPEYRGSLKRAGLLTRDPRMKERKKPGLKAARRSPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.