PharMolix/UniProtQA huggingface dataset:
Protein: FADA_SALTY
Sequence: MEQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPSLTAATLDDIYWGCVQQTLEQGFNIARNAALLAEIPHSVPAVTVNRLCGSSMQALHDAARMIMTGDAQVCLVGGVEHMGHVPMSHGVDFHPGLSRNVAKAAGMMGLTAEMLSRLHGISREMQDQFAARSHARAWAATQSGAFKTEIIPTGGHDADGVLKQFNYDEVIRPETTVEALSTLRPAFDPVSGTVTAGTSSALSDGAAAMLVMSESRARELGLKPRARIRSMAVVGCDPSIMGYGPVPASKLALKKAGLSASDIDVFEMNEAFAAQILPCIKDLGLMEQIDEKINLNGGAIALGHPLGCSGARISTTLINLMERKDAQFGLATMCIGLGQGIATVFERV
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.  Involved in the aerobic and anaerobic degradation of long-chain fatty acids (By similarity).
What are the official names of this protein?
3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_SOLM1
Sequence: MKILLVAGGWSSERAVSLSGAVQIEKALTSLGHEVVPYDLSHDFPGFVRRAKACDFVFLSLHGAPGEDGLPQALLDAAGVPYQGSGPAGSFLALNKAASKQLFLEACLPTPRWTFVPRDAGTSARPDFPLPWFVKPNLGGSSIHMTLVRRAEELPAALEKVFAHGDDALIEEGLSGPELTCAVLGDEALPPILIRPKAGEFFDYASKYEPDAADEICPAPVEPAVTEELSRLSLAAHRVLGLCGYSRADFILAPEGLRLLEVNTLPGMTPTSLLPRAAATAGLSFADLIARLIELGLAQQAKRP
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLTOP_MOUSE
Sequence: MATNYSANQYEKAYLPTYLQNWSPARPTKEKIAAHEGYTQIIANDRGHLLPSVPRSKASPWGSFMGTWQMPLKIPPAKVTLTARTTTAADNLTKWIHKNPDLLNACNGLRPEISGKPFDPDSQTKQKKSVTKTVQQAPNPTIIPSSPVIQGDNPDEPQSSHPSAGHTPGPQTPVNSPNNPPPSPCKSTK
What is the function of this protein?
Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells.  Regulates basal body docking and cilia formation in multiciliated lung cells.  Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear.
What are the official names of this protein?
Protein Flattop, Cilia- and flagella-associated protein 126.
What is the protein family that this protein belongs to?
Belongs to the Flattop family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium. Apical cell membrane. Note=Localizes to the apical cell membrane, the basal body and the primary cilium in monociliated node cells. Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme (By similarity).
Protein: DAPB_BRADU
Sequence: MSDMRLIVAGAGGRMGRALTRAIAESKGAVLAGALEAPGSEMLGKDAGVLAGLPANGIKLSADLWAMSKEADGILDFTVPAATIANVAIAAERGIVHVIGTTGLSGSDNAVIKSVTNRAVVVQSGNMSLGVNLLAAVVKRVAKALDQSFDIEIVETHHRMKIDAPSGTALMLGQAAAAGRGISLDEHADRGRDGITGARKPGNIGFASLRGGTAAGDHSVSFLGPFERLTLSHQAEDRMLFAHGALKAALWAHGKKPGHYSMADVLGLADI
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2851_MYCTO
Sequence: MTEALRRVWAKDLDARALYELLKLRVEVFVVEQACPYPELDGRDLLAETRHFWLETPDGEVTCTLRLMEEHAGGEKVFRIGRLCTKRDARGQGHSNRLLCAALAEVGDYPCRIDAQAYLTAMYAQHGFVRDGDEFLDDGIPHVPMLRPGSGQVERP
What are the official names of this protein?
UPF0039 protein MT2917.
What is the protein family that this protein belongs to?
Belongs to the UPF0039 (ElaA) family.
Protein: CCMB_BRADU
Sequence: MTALSALIRRDIRIALRVGGGALIGVLFFLTVVVLMPFAVGPDLALLSRLGPAILWLGALLASLLTLDRLFMADHEDGSLDLITMSRTPLELACAAKALAHWLAAGLPLIVATPVLGLLLNLDMVATGAVALTLLAGTPALTFTGMIGAALAVTLHRGGLLMAVLVLPLSIPVLIFGVAASQAVIVGPMSFGAPFSILCALSLVSLVIGPFAAAASLRHGLD
What is the function of this protein?
Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.
What are the official names of this protein?
Heme exporter protein B, Cytochrome c-type biogenesis protein CycW.
What is the protein family that this protein belongs to?
Belongs to the CcmB/CycW/HelB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS20_AERHH
Sequence: MANIKSAKKRALQSEKRRQHNASRRSMTRTYLKKVIAAIASGDKAAATAAFAVAQPIMDRMATKGLIHKNKAARHKSRLSAQIKAMA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: AMER3_MOUSE
Sequence: MELRRGKTFIKSSVQISHEKLIDSPAKEDPDKWPLSLGEQQRAYGEKSSQTSPCSQGYGRCPNKEVLSDPEGGPVPLCGTTFKLVRKSKTHDSVPGAVKAAAPTGQMVGSTSFSETPGGQRMIDYRHFVPQMPFVPAVAKSIPRKRISLKRSKKCFRNLFHMRRSKTENLASLSAKGKNLSPSGVPAQQGTAFLSMGEGLGLDSLCQDLSDSEFLHDSPFDLCSALCEDVASLKSFDSLTGCGEIFADGSSVPSVELKDGPESPAHSPQALDCKTPCGPAQGGMEQLMSPAQNEASDFNKFWDSVNRSVQQQQRALMGPWLTSPEGTETDQTRLDTSGLAELPLFPCRGPPSGSKASSIDTGTPKSEQPESVSTSDEGYYDSFSPGLEEEKKEAASPGTPAATFPRDSYSGDALYELFYDPSEAPVGPILDDDCVSESLSGPALGTPLSMCSFRVGAEENLAPAPGPDLLSQGFLQSTWKGKECLLKLCDTELAITMGIVNWLRRTPPATSPTPASTPAPTPALVLREPAAPPDPHRVLRGASVGVKGREDQATTCFPPSRQEPWAHSGTKNLLVRECEVLGEPARGSKTPSKDDSLEEGTQDFSEGQSSSEATMTSISGNNKAVTSATCLSSQKELGTPGNLRYSQGPLRPGHRGSALDPGPMLVGCVTHVAALQIYPDSNSPRQDKGNGLFWKPQAWGPNILQKNPISSKPNEAAGCGLSSSASPQDQKCRDLFLDLNQLKLEPSRLGPQACSSVDSQPQQLCPRAPEQVPHRGSVGS
What is the function of this protein?
Regulator of the canonical Wnt signaling pathway.  Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity).
What are the official names of this protein?
APC membrane recruitment protein 3, Amer3, Protein FAM123C.
What is the protein family that this protein belongs to?
Belongs to the Amer family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Note=Translocates to the cell membrane following binding to PtdIns(4,5)P2.
Protein: KUP1_LEGPC
Sequence: MRYSSYEMKKNRFTYGLALGALGVVFGDIGTSPLYALKVTLSGIPINQFNILGVLSLIFWSLIIVVSFKYLMIIFRADNDGEGGILALLALMKHKSTKYQPLFYIVAIFGAGLLLGDGMLTPAISVVSAVEGLGTLSDKLYPYVLPIASVILVLLFSLQAKGTARIGYLFGPLILIWFITIAILGILQIVEHPVVLQAINPYYAIAFLVDEGLRGYFLLGGIFLVVTGGEALFADIGHFGKNPIRFSWFFIALPCLLLNYFGQGANLIVRPEEISNPFFMIAPPWFYLPLIIIATVATVIASQAVISATFSLTKQAVLLGLCPKIPIVQTSMLHSGQIYVPQINFILFIGTMAFCLAFKTSDNLAHAYGIAVNLEMLLVDAMVAYAAVSIWRWSTFNVIFLFGLFLLIDLAFLGANTHKFITGGWVPIVLAFVIAFIMYSWRYGLEYLRDNFYMNKEDISKILKQLQYKSLNQLPGVSAIFITDVYDKSGGSFLHFLKLNRSVPENVLIVNYIVDNIPYVHYSQRYEIVCLDEKVCKLVIHYGFMETINIPRSLEKACNKNILPFKFNVDTATFMVEIPNIMASKEKRSLSFYWQEKLFAFLMRNYSANLNIEFYKLPYNRTIAIGTYCIL
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 1.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NU6M_SYNAN
Sequence: MTYFMLFLGLCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLMSLGMSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPEAWGDWRVVGYGVSFIVVLAAGAVVGGLVGCWDSGVITVDSVGMLSVRLDFSGVAMFYSCGVGMFLVAGWGLLLTLFVVLELVRGLSCGAIRAV
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: CH60_GEOSM
Sequence: MAAKLIKFDQEARNCILKGVNTLADAVKVTLGPKGRNVVIEKSYGAPLITKDGVTVAKEIELEDKFENMGAQLVKEVASKTSDVAGDGTTTATVLAQAIYRQGAKLVAAGHNPMEIKRGLDQAVEALVAELKNISKPIKDHKEIAQVGTISANNDKTIGDIIAEAMEKVGKEGVITVEEAKAMETTLETVEGMQFDRGYLSPYFVTDPERMEAAMDNVAILIHDKKIANMKDLLPVLEQTAKSGRPLLIIAEDIEGEALATLVVNKLRGVLNVCAVKAPGFGDRRKAMLEDIAILTGGKVISEEVGFKLENTTLDMLGQAKKITVDKDNTTIIDGFGAEADIQGRVKMIRAQIDETSSDYDREKLQERLAKLVGGVAVIKVGAATEIEMKEKKARVEDALHATRAAVDEGIVPGGGVAYLRAMKVLENLQLAPEQQFGVNVIKRALEEPIRQISQNAGVDGSIVVDKVKNGKDAFGYNAADDVYVDMIEAGIIDPTKVSRSALQNAASVAGLMMTTEAMIADKPKEEGAMPAMPGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AUXI_BOVIN
Sequence: MDSSGASSPDMEPSYGGGLFDMVKGGAGRLFSNLKDNLKDTLKDTSSRVIQSVTSYTKGDLDFTYVTSRIIVMSFPLDSVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFCNLYSTPGPAVRLLYAKRPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSITVSPVPFFNKQRNGCRPYCDVLIGETKIYTTCADFERMKEYRVQDGKIFIPLSITVQGDVVVSMYHLRSTIGSRLQAKVTNTQIFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQLFQVTLDVELQPHDKVMELTPPWEHYCTKDVNPSILFSSHQEHQDTLVLGGQAPIDIPPDNPRHFGQGGFFSTLCWQDQKSEKSFCEEDHAALVNQESEQSDDELLTLSSPHGNANGDKPHAARKPSKKQQEPAAPAPPEDVDLLGLEGSAVSKNFSSPAAPPSNSELLSDLFGGGGAAGPVQSGQSGVDDVFHPSGPTSTQSTPRRSATSTSASPTLRVGEGATFDPFGAPSKPSGQDLLGSFLNTASASSDPFLQPTRSPSPTVHASSTPAVNIQPDVSGAWDWHTKPGGFGMGSKSAATSPTGSSHGTPTHQNKPQTLDPFADLGTLGGSSFASKPSTPTGLGGGFPPLSSPQKASPQPMGGGWQQGGGYNWQQTQSKPQSSMPHSSPQNRPNYNVSFSSMPGGQNERGKAAANLEGKQKAADFEDLLSGQGFNAHKDKKGPRTIAEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTMHTVLWAGETKWKPVGMADLVTPEQVKKVYRKAVLVVHPDKATGQPYEQYAKMIFMELNDAWSEFENQGQKPLY
What is the function of this protein?
Recruits HSPA8/HSC70 to clathrin-coated vesicles and promotes uncoating of clathrin-coated vesicles (PubMed:15502813).  Plays a role in clathrin-mediated endocytosis in neurons (By similarity).
What are the official names of this protein?
Putative tyrosine-protein phosphatase auxilin, DnaJ homolog subfamily C member 6.
Protein: RL19_BRADU
Sequence: MNLIKQLEQEQFDKLSAGKDIPEFGPGDTVIVNVKVVEGDRTRVQAYEGVCIGRSGGGLNESFTVRKISYGEGVERVFPVMSPMIDSIKVVRRGKVRRAKLYYLRNLRGKSARIVEKQDRQAAVGE
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RUVB_BACCR
Sequence: MSIIVERLLSRESAYGDAVEDFPLRPQTLRQYIGQNKAKHNLEVFIEAAKMREETLDHVLLYGPPGLGKTTLANIIANEMGVNVKTTSGPAIGRPGDLAAVLTALQPGDVLFIDEIHRLHRSIEEVLYPAMEDFCLDIVIGKGPSARSVRLDLPPFTLVGATTRAGALSAPLRDRFGVLSRVEYYTVDQLSAIVERTAEVFEVEIDSLAALEIARRARGTPRIANRLLRRVRDFAQVRGNGTVTMEITQMALELLQVDKLGLDHIDHKLLLGIIEKFRGGPVGLETVSAPIGEESHTIEDVYEPYLLQIGFLQRTPRGRIVTPLAYEHFGMEIPKV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: SVOPL_MOUSE
Sequence: MAAKQTEPVTIISLRKLSQAAPEPQQKETKTFTVEDAVETIGFGRFHIALFLIMGSTGVVEAMEIMLIAVVSPVIRCEWQLENWQVAFVTTMVFFGYMVSSILFGLLADRYGRWKILLLSFLWGAYFSLLTSFSPSYIWFVFLRTMVGCGVSGHAQGLIIKTEFLPTKYRGYMLPLSQVFWLAGSLLIISMASVVIPTIGWRWLIRIASIPGIILIMAFKFIPESARFNVSTGNTQAALNTLESIAKMNRSVMPEGQLVEPILEKRGRFADLLDSKYLRTTLQIWIIWLGISFAYYGVILASAELLERDLVCGSKSESEPEVVETTGDSGEGLSPCYCHIFAPSDYRTMIISTLGEIALNPLNILGINFLGRRLSLSITMGCTALFFLLLNICTSSAGLIGFLFMLRALVAANFNTIYIYTAEVYPTPMRAIGMGTSGSLCRIGAMVAPFISQVLMSASFLGALCLFSSVCVVCAISAFTLPIETKGRALQQIK
What are the official names of this protein?
Putative transporter SVOPL, SVOP-like protein.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL1_CERSK
Sequence: MAKVGKRTRSAREAFVGKDLISVEDAVALIKQAASAKFDETLEVAMNLGVDPRHADQMVRGVVTLPNGTGKTVRVAVFARGAKADEAKAAGADIVGAEDLMETIQSGKIEFDRCIATPDMMPLVGRLGKILGPRNLMPNPKVGTVTMDVKSAVEAAKGGEVQFKVEKAGVIHAGVGKMSFEADKLAQNVRAFVDAVNRAKPAGAKGTYLKKVSLSSTMGPGVSVDLTSATSH
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: SEPH_EMENI
Sequence: MVSRSNEGPEAPHPASRTPGAPAKGRLTRLGSSPSKRDDKAKDDRMGKTSAKDVAELKDYQLGDCLGRGAFGSVYRALNWNTGETVAVKQIKLADLPKSELRVIMLEIDLLKNLDHPNIVKYQGFVKSAETLNIILEYCENGSLHSIAKNFGRFPETLVGVYMSQVLHGLLYLHDQGVIHRDIKGANILTTKEGLVKLADFGVASRTTGLSESSVVGTPYWMAPEVIELSGATTASDIWSLGCTVIELLEGKPPYYNLQPMPALFRIVNDDHPPLPQGASPAVKDFLMQCFQKDPNLRVSARKLLKHPWIVNARRSDSVVPKKSTEYEEAVKSVQEWNEALRSPESNALRRGTRNENQNPPSLRLDTRHTPTKVTLPSPVSRIVADKFSSPSSGEEDNWDDDFATAISPSALQLPHLRPHDNFGGMLSSEKLKAFASLDGTVLKSDESFEESDDPFKGSLLAGEHDPLKTIRPPPSQQANSGTSQSQNGPYGAHMRRGPPLNTAITPVYGGQMLQNSSSPIRQQRPPLFYKENSVEDYSDLISANEDVLDRKISAFQESDEHKDLADTGRSREVIRYQSSYEQEDTPRIGRQISVKRYRGTVEIQQFAENEHDEDFSDILGVDGVTLDKAESDDGSNKSTLMLNTKLSNNSWLGDLDDEDDPFALLEEGLDETDLEANIARDKHARLRSQVEGLVGSLKTSQDEEVLGDISEQLLAVFCDFPETKNIIISAHGMLPILEILDLCRRRDITLCLLKIVNAIIYDDYEIQENLCFVGGIPIINEFAAKKYPREIRLEAAAFVQQMYQTSTLTLQMFVSAGGLNVLVEFLEDDYEDERDLVLVGVNGIWSVFELQGSTPKNDFCRILSRSSVLDPLSLVLSRVLDEEGELAEVVEGRIANIFFIFSQAENHVKEMVSERTVLHRVLKELKRMTPAHQITMLKFIKNLSMLSTTLDSLQNSNAIDVLTDLLRSTIKRPHFREVSNQILNTIYNMCRLNKSRQEDAALNGIVPLLQKIVKTERPLKEFALPILCDMAHSGKVGRRELWRNKGLAFYISLLSDPYWQVTALDAIFIWLQEETAKVEEHLLENRYDQPSFTDAIVRCLTLSKANAFENILEPLQKLLRLSPPIASTLARPDLFSRLGQKLHHSKAAVRLNLLRIISSICDSSEQQGGLLASYGLLDSIRELEHDPAILVRDMAGKLIQSSERNDSYGLCKLKPNVRRGSTSATSPGLLANQSAPVTPQLSRQNQSKGYYDSRETQRRPRSAISGSALALRPGSRDGPTPGIVGGANGSAGASRNRIARGVSNRLSHIELLPNDDDRIPSSITRRSSVLPRRRRLTQFEAERGS
What is the function of this protein?
Required for early events during cytokinesis including localization of cytoskeletal components to the cytokinetic ring.
What are the official names of this protein?
Cytokinesis protein sepH, Serine/threonine-protein kinase sepH.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC7 subfamily.
Protein: TIP32_MAIZE
Sequence: MSTATGVRAGRRFTVGRSEDATHPDTIRAAISEFIATAIFVFAAEGSVLSLGKMYHDHSTISTAGGLVAVALAHALGLAVAVAVAVNVSGGHVNPAVTFGALVGGRVSLVRAVLYWAAQLLGAVAATLLLRLATGGARPPGFALASGVGDGHAVLLEAVMTFGFVYAYYATVVDPKRGHLGTIAPLAVGFLLGANVLAGGPFDGAGMNPARVFGPALVGWRWRHHWVYWLGPFLGAGLAGLVYEYLLIPPADAVPHTHQPLAPEDY
What is the function of this protein?
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
What are the official names of this protein?
Aquaporin TIP3-2, Tonoplast intrinsic protein 3-2, ZmTIP3-2, ZmTIP3;2.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. TIP (TC 1.A.8.10) subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast.
Protein: Y4036_STRCO
Sequence: MIRHLVLFKLNDGVGRDEPRVLAGVEAFRALGGQIEDLRFWECAWNISDRPIAYDFAINSAVDDADALKRYLEHPAHQAGVALWREFATWVIADYEF
What are the official names of this protein?
Uncharacterized protein SCO4036.
Protein: NSE2_RAT
Sequence: MPGRSSTNSGSTRYISFSGVESALSSLKTFQSCISSGMDTVSSVALDLVETQTEVSSEYSMDKAMVEFAKMDRELNHYVKAVQSTINHVKEERPEKVPDLKLLVEKKFLALQDKNSDADFKENEKFVQFKQQLRELKKQYGIHADRENDGIEGMDEDMIVTQSQTNFICPITQLEMKKPVKNKMCGHTYEEEAIVRMIESKHKRKKKACCPKIGCSHTDMRMSDLIPDEALRRAIESHNKKKKRHSE
What is the function of this protein?
E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand break repair by homologous recombination.  Is not be required for the stability of the complex.  The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks.  Acts as an E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TSNAX, the shelterin complex subunits TERF1, TERF2, TINF2 and TERF2IP, RAD51AP1, and maybe the cohesin components RAD21 and STAG2.  Required for recruitment of telomeres to PML nuclear bodies.  Required for sister chromatid cohesion during prometaphase and mitotic progression.
What are the official names of this protein?
E3 SUMO-protein ligase NSE2, E3 SUMO-protein transferase NSE2, MMS21 homolog, Non-structural maintenance of chromosomes element 2 homolog, Non-SMC element 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the NSE2 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere. Nucleus, PML body. Note=Localizes to PML nuclear bodies in ALT cell lines.
Protein: YBEY_CARHZ
Sequence: MTEITNLQDKVDVDETLLNIITQAVSLTLNEEGRAGVVSIALVDNNYIQSLNREYRQKDVPTDVLSFPLADDKDDEVLGDVVISLEKAAEQAKEYGHSFFREVAFLTVHGVLHLLGHDHYEEEETRIMREKEEKILSALGLER
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMIF_BACAC
Sequence: MGSSGSMVKPISGFLTALIQYPVPVVESRADIDKQIKQIIKTIHSTKAGYPGLELIVFPEYSTQGLNTKKWTTEEFLCTVPGPETDLFAEACKESEVYGVFSIMERNPDGGEPYNTAIIIDPQGEMILKYRKLNPWVPVEPWKAGDLGLPVCDGPGGSKLAVCICHDGMFPEVAREAAYKGANVLIRISGYSTQVSEQWMLTNRSNAWQNLMYTLSVNLAGYDGVFYYFGEGQVCNFDGTTLVQGHRNPWEIVTAEVYPELADQARLGWGLENNIYNLGSRGYVATPGGVKENPYTFVKDLAEGKYKVPWEDEIKVKDGTIYGYPVKKTIHS
What is the function of this protein?
Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide.
What are the official names of this protein?
Formamidase, Formamide amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
Protein: DP2L_PYRAB
Sequence: MELPKEMEEYFEMLQREIDKAYEIAKKARAQGKDPSLDVEIPQATDMAGRVESLVGPPGVAKRIRELVKEYGKEIAALKIVDEIIEGKFGDLGSREKYAEQAVRTALAILTEGIVSAPIEGIANVKIKRNTWADNSEYLALYYAGPIRSSGGTAQALSVLVGDYVRRKLGLDRFKPSEKHIERMVEEVDLYHRAVTRLQYHPSPEEVRLAMRNIPIEITGEATDDVEVSHRDVPGVETNQLRGGAILVLAEGVLQKAKKLVKYIDKMGIEGWEWLKEFVEAKEKGEPKEEGKEESLAESTLEETKVEVDMGFYYSLYQKFKEEIAPSDKYAKEVIGGRPLFSDPSKPGGFRLRYGRSRASGFATWGINPATMILVDEFLAIGTQLKTERPGKGAVVTPVTTIEGPIVKLKDGSVLRVDDYNLALKVREDVEEILYLGDAVIAFGDFVENNQTLLPANYCEEWWILEFVKALKEIYEVHLEPFTENEEESIEEASDYLEIDPEFLKEMLRDPLRVKPPVELAIHFSEVLGIPLHPYYTLYWNSVEPKDVEKLWRLLKNYAEIEWSNFRGIKFAKKIVISQEKLGDSKRTLELLGLPHTVRDGNVIVDYPWAAALLTPLGNLNWEFMAKPLYATIDIINENNEIKLRDRGISWIGARMGRPEKAKERKMKPPVQVLFPIGLAGGSSRDIKKAAEEGKVAEVEIAFFKCPKCGHVGPEHLCPNCGTRKELLWVCPRCNAEYPESQAEGYNYTCPKCNVKLRPYAKRKIRPSELLNRAMENVKVYGVDKLKGVMGMTSGWKMPEPLEKGLLRAKNDVYVFKDGTIRFDATDAPITHFRPREIGVSVEKLRELGYTHDFEGKPLVSEDQIVELKPQDIILSKEAGRYLLKVAKFVDDLLEKFYGLPRFYNAEKMEDLIGHLVIGLAPHTSAGIVGRIIGFVDALVGYAHPYFHAAKRRNCFPGDTRILVQIDGVPQKITLRELYELFEDERYENMVYVRKKPKREIKVYSIDLETGKVVLTDIEDVIKAPATDHLIRFELEDGRSFETTVDHPVLVYENGRFIEKRAFEVKEGDKVLVSELELVEQSSSSQDNPKNENLGSPEHDQLLEIKNIKYVRANDDFVFSLNAKKYHNVIINENIVTHQCDGDEDAVMLLLDALLNFSRYYLPEKRGGKMDAPLVITTRLDPREVDSEVHNMDIVRYYPLEFYEATYELKSPKELVGVIERVEDRLGKPEMYYGLKFTHDTDDIALGPKMSLYKQLGDMEEKVRRQLEVAKRIRAVDEHGVAEKILNSHLIPDLRGNLRSFTRQEFRCVKCNTKFRRPPLNGKCPVCGGKIVLTVSKGAIEKYLGTAKMLVTEYNVKNYTRQRICLTERDIDSLFENVFPETQLTLIVNPNDICQRLVMARTGEVNKSGLLENLSNGSKKTEKAEKAEKPRKKSDEKPKKKRVISLEEFFSRKSK
What is the function of this protein?
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction.  Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase II large subunit, Pol II, Exodeoxyribonuclease large subunit.
What is the protein family that this protein belongs to?
Belongs to the archaeal DNA polymerase II family.
Protein: RL31_ALCBS
Sequence: MKAEIHPDYQTATYTCSCGNVIETRSTKGGDMALDVCSACHPFYTGKQKQADSGGQIDKFKQRFGMMRSKKD
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: TGT_NITSB
Sequence: MDFFIDATDNNARACTIKTSHSTIKTPVFMPVGTAASVKSLDTVDLRDILQTQIILANTYHLYLRPGDNVVKKLGGLHGFTGYNRSFLTDSGGFQAFSLSDISKANERGIEFQSHIDGSKHFFTPQKVLDIQYNLGSDIMMILDDLVALPATKERLALSVDRTTRWAQESIKYHKKMQAQGIGTNQNIFAIIQGGTDYEFRKKSAMELTALDFDGFAIGGLSVGEENSVMYNTVEFTTPFMPKNKPRYLMGVGTPEDLVECIDRGVDMFDCVMPTRNARNGTIFTSFGRLNIKAAKYKLDQNPIDEACSCYTCQNYTRAYLNHLYRAKELTYYRLASIHNLHYYLTLMKEAREAIEKGEYKAFKKAFYARRQS
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.