PharMolix/UniProtQA huggingface dataset:
Protein: YPEL5_BOVIN
Sequence: MGRIFLDHIGGTRLFSCANCDTILTNRSELISTRFTGATGRAFLFNKVVNLQYSEVQDRVMLTGRHMVRDVSCKNCNSKLGWIYEFATEDSQRYKEGRVILERALVRESEGFEEHVPSDNS
What is the function of this protein?
Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1 (By similarity).  Required for normal cell proliferation (By similarity).
What are the official names of this protein?
Protein yippee-like 5.
What is the protein family that this protein belongs to?
Belongs to the yippee family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Midbody. Note=Deteted in nucleus and at the centrosome during interphase. During mitosis, detected on the mitotic spindle, at spindle poles and at the midbody.
Protein: BXA2_CLOBJ
Sequence: MPFVNKQFNYKDPVNGVDIAYIKIPNAGQMQPVKAFKIHNKIWVIPERDTFTNPEEGDLNPPPEAKQVPVSYYDSTYLSTDNEKDNYLKGVTKLFERIYSTDLGRMLLTSIVRGIPFWGGSTIDTELKVIDTNCINVIQPDGSYRSEELNLVIIGPSADIIQFECKSFGHDVLNLTRNGYGSTQYIRFSPDFTFGFEESLEVDTNPLLGAGKFATDPAVTLAHELIHAEHRLYGIAINPNRVFKVNTNAYYEMSGLEVSFEELRTFGGHDAKFIDSLQENEFRLYYYNKFKDVASTLNKAKSIIGTTASLQYMKNVFKEKYLLSEDTSGKFSVDKLKFDKLYKMLTEIYTEDNFVNFFKVINRKTYLNFDKAVFRINIVPDENYTIKDGFNLKGANLSTNFNGQNTEINSRNFTRLKNFTGLFEFYKLLCVRGIIPFKTKSLDEGYNKALNDLCIKVNNWDLFFSPSEDNFTNDLDKVEEITADTNIEAAEENISLDLIQQYYLTFDFDNEPENISIENLSSDIIGQLEPMPNIERFPNGKKYELDKYTMFHYLRAQEFEHGDSRIILTNSAEEALLKPNVAYTFFSSKYVKKINKAVEAFMFLNWAEELVYDFTDETNEVTTMDKIADITIIVPYIGPALNIGNMLSKGEFVEAIIFTGVVAMLEFIPEYALPVFGTFAIVSYIANKVLTVQTINNALSKRNEKWDEVYKYTVTNWLAKVNTQIDLIREKMKKALENQAEATKAIINYQYNQYTEEEKNNINFNIDDLSSKLNESINSAMININKFLDQCSVSYLMNSMIPYAVKRLKDFDASVRDVLLKYIYDNRGTLVLQVDRLKDEVNNTLSADIPFQLSKYVDNKKLLSTFTEYIKNIVNTSILSIVYKKDDLIDLSRYGAKINIGDRVYYDSIDKNQIKLINLESSTIEVILKNAIVYNSMYENFSTSFWIKIPKYFSKINLNNEYTIINCIENNSGWKVSLNYGEIIWTLQDNKQNIQRVVFKYSQMVNISDYINRWIFVTITNNRLTKSKIYINGRLIDQKPISNLGNIHASNKIMFKLDGCRDPRRYIMIKYFNLFDKELNEKEIKDLYDSQSNSGILKDFWGNYLQYDKPYYMLNLFDPNKYVDVNNIGIRGYMYLKGPRGSVVTTNIYLNSTLYEGTKFIIKKYASGNEDNIVRNNDRVYINVVVKNKEYRLATNASQAGVEKILSALEIPDVGNLSQVVVMKSKDDQGIRNKCKMNLQDNNGNDIGFIGFHLYDNIAKLVASNWYNRQVGKASRTFGCSWEFIPVDDGWGESSL
What is the function of this protein?
Responsible for host epithelial cell transcytosis, host nerve cell targeting and translocation of light chain (LC) into host cytosol.  Composed of 3 subdomains; the translocation domain (TD), and N-terminus and C-terminus of the receptor-binding domain (RBD).  The RBD is responsible for the adherence of the toxin to the cell surface.  It simultaneously recognizes 2 coreceptors; polysialated gangliosides and the receptor protein SV2 in close proximity on host synaptic vesicles (PubMed:28252640, PubMed:29649119).  The N-terminus of the TD wraps an extended belt around the perimeter of the LC, protecting Zn(2+) in the active site; it may also prevent premature LC dissociation from the translocation channel and to protect toxin prior to translocation (By similarity).  The TD inserts into synaptic vesicle membrane to allow translocation into the host cytosol (By similarity).
What are the official names of this protein?
Botulinum neurotoxin type A2, BoNT/A, BoNTA2, Bontoxilysin-A, BOTOX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M27 family.
What are the subcellular locations of this protein?
[Botulinum neurotoxin A2 light chain]: Secreted. Host cytoplasm, host cytosol. SUBCELLULAR LOCATION: [Botulinum neurotoxin A2 heavy chain]: Secreted. Host synapse, host presynaptic cell membrane. Host cytoplasmic vesicle, host secretory vesicle, host synaptic vesicle membrane; Multi-pass membrane protein.
Protein: GLMS_OCEIH
Sequence: MCGIVGYIGQNDTKEILLTGLEKLEYRGYDSAGIATLNDNGVHVTKVKGRIATLREDVDTTIDSTMGIGHTRWATHGVPSVMNAHPHQSTSERFTIVHNGVIENYNDIKNEYLADVSFISETDTEVIVQLIEKLHEKYQDTKKAFSEAMSLLKGSYAIGLIDAEDSETLYVSKNKSPLLVGLGDGFNLVASDAMATLRETDQYLEIFDKEIVLVSRNYVEVQTLDGQVVERKPFTAEIDASDTEKGTYPHFMLKEIDEQPIVMRKIIQEYQNDNGQLKLDQDIRTAMKDADRIYIIAAGTSYHAGLVGKEFIEKLANIPVEVHVASEFSYNMPLLSEKPLFVFISQSGETADSRAVLVKIKELGHPALTLTNVPGSTLSREANYTMHLHAGPEIAVASTKAYTAQIAVLAILAVDTARVKGLELDFEPLQELAIVANAMEVLTDQKEELEQLARDYFGTTRNAFFIGRSTDYHVAQEAALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVIALTTQENVNYSIRGNVQEVVARGANAMVVSMKGLEQDEDAFVIPHVHELLTPLASVIPMQLLAYYAALHRDCDVDKPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGUA_SALTI
Sequence: MAQGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRAPRPGEVHGEHYFFVNHDEFKTMIGREAFLEHAEVFGNYYGTSRETIEQVLATGVDVFLDIDWQGAQQIREKMPQARSIFILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEMSHYAEYDYLIVNDDFDTALSDLKTIIRAERLRMSRQKQRHDALISKLLAD
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDPAS_THEAC
Sequence: MQSIILFIPALIANSGAVITGGHFIIDRGKKFIDGRRILGNGKTLSGYAGGIAIGTVTGFIIYLISTLFNYALGTYGTLAEAIIIPFIMATGSLTGDIAGSFVKRRIGIDRGGKGGLLDQWPFALMAFLFLYIFERPFFMYHYFYVTMIVILVIVPPIHRAVNIIGYKMHKKDVPW
What is the function of this protein?
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP.  This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
CDP-archaeol synthase, CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-archaeol synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RBFA_ACIBY
Sequence: MAGGQRLKRMADSVQRELSELIRQELKDPRLGGLVTISGVKVSPDLGYADVYVTVMGRELSDDQNEVAHRETLDILNKASGFLRQELSRRIKTRITPRLRFHYDKTNAYGNYMFGLIEKAVQDLPKRESDDEE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_CHLMU
Sequence: MENRTEMSQLRASKKDSKISHVLLMAIKLYLESGQPVGSKLLKETYCSDLSSATIRNYFAQLETDGFLRKNHISGGRIPTDLAFRYYADHCSPVLEQEEISIIQQKLKELPEYSKNIVKDLQKASEILSEILQLPVCFSSPRFESDSVTNIQLVSIDDLRVVFVLSTEFGQLFTDVLWLPEQLPENSLKRIESFLQNYLRKHPSSVPLSQKEEDLGMTLYNEVVVRYLTRYCHFSEEDLYQTGLSRLLKYEVFKDPETLAQGLSFFENRKHMCQLLNSHLHKKAPTTFIGRELSDIVGNADPSCAVITVPYYMDRTPLGAFGVLGPMNLPYQQVFGTLSLFTERLKTILTQSFYKFKLSFRRPCPTDPRCSQKPAELTRRSSIKLLPAKELT
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: YQGF_CLOBK
Sequence: MRILGLDIGDRTIGIAISDPLGFTAQGITTIRRKSEAYDLEEIKKICDKYEVDTIVSGLPKNMNGTLGPQSEKVLEFCDLIKEHLNIEIKMWDERLTTVAATRAMLEADLSRSKRKKIVDKVAATYILQGYLDSLSK
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUTA_CAUVC
Sequence: MQVGVFIPIGNNGWLISETSPQYMPSFELNKEITQKAEKYGFDFALSMIKLRGFGGKTEFWEHNLESFTLMAGLAAVTSKIKIFATVATLTIPPAIVARMASTIDSIAPGRFGVNLVTGWQKAEYSQMGLWPGEAHYTDRYNYLAEYTTVLKDLLETGVSDFKGKYFTMDDCRVSPHPKETKLICAGSSDEGLAFTAQYADYSFALGKGTNTPTAFASVNRRLEAAAAKTGRDVQSFILFMVIADETDEKAMAKWQKYRDGADQEALAWLTQQAAPNAKAGATTNTQQLAAPESAVNLNMGTLVGSYESIARMMDEIAQVPGTAGVLLTFDDFVQGVEDFGTKIQPLMKSRKGG
What is the function of this protein?
Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide.  The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN.  Requires the flavin reductase RutF to regenerate FMN in vivo.
What are the official names of this protein?
Pyrimidine monooxygenase RutA.
What is the protein family that this protein belongs to?
Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
Protein: ERD2_PLAFA
Sequence: MNIFRLIGDILHLVSMYILIMKLKKSKNCIGISCRMQELYLIVFLCRYIDLFFVFVSFYNTVMKITFILTIAYTIYLIRLKLPISQTYNRKVDNFKSEKYLIPPCLVLSLLTCKTYNLYNILWSFSIWLESVAILPQLVLLEKQREVENITSHYVITMGLYRAFYILNWIYRYFFDDKPYINVVGWIGGLIQTLLYIDFFYYFALAKWYGKKLVLPFNGEV
What is the function of this protein?
Required for the retention of luminal endoplasmic reticulum proteins.  Determines the specificity of the luminal ER protein retention system.  Also required for normal vesicular traffic through the Golgi (By similarity).
What are the official names of this protein?
ER lumen protein-retaining receptor.
What is the protein family that this protein belongs to?
Belongs to the ERD2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SYY_YERE8
Sequence: MTSSNLIKQLQERGLVAQVTDEDALAERLAQGPISLYCGFDPTADSLHLGHLVPLLCLKRFQLAGHRPVALVGGATGMIGDPSFKASERKLNTEDTVNEWVEKIRRQVSPFLDFDCGDNSAIAANNYDWFGGMNVLTFLRDIGKHFSVNQMINKEAVKQRLNRDDSGISFTEFSYNLLQAYDFACLNKAHGVALQIGGSDQWGNITSGIDLTRRLHQQQVYGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFTFMNLEEINALEEEDKNSGKAPRAQYVLAENVTGMVHGEEGLAAAKRITASLFSGDLNDMTEADFAQLAQDGMPTIELTRDADLQQALVNAELVPSRGQARTMISSNAVAINGEKQSDPEYAFTDADRLFGRYTLLRRGKKHYCLISWL
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M1111_BOMMX
Sequence: MNFKYIVAVSFLIASAYARSEENDEQSLSQRDVLEEESLREIRGIGTKIIGGLKTAVKGALKELASTYVNGKRTAEDHEVMKRLEAVMRDLDSLDYPEEASERETRGFNQEEIANLFTKKEKRILGPVLGLVGSALGGLIKKIG
What is the function of this protein?
Maximin-H11 shows antimicrobial activity against bacteria and against the fungus C. albicans.  Shows strong hemolytic activity (By similarity).
What are the official names of this protein?
Maximins 11/H11.
What is the protein family that this protein belongs to?
Belongs to the bombinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL21_LACH4
Sequence: MYAIIKTGGKQYKVAEGDSVFVEKLDAEEGSSVTFDEVILVANGDDVKVGTPLVDGAKVTAKVEKQGKEKKVVTFKYKPKKHSHSKYGHRQPYTKVTVEKIEA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: CRFR1_CHICK
Sequence: MVPGPRPALLLLLFLLQAFLLWDSPVAASIQEQYCESLLPTTNHTGPQCNASVDLIGTCWPRSAVGQLVARPCPEYFYGVRYNTTNNGYRECLANGSWAARVNYSQCQEILSEEKRSKLHYHIAVIINYLGHCVSLGTLLVAFVLFMRLRSIRCLRNIIHWNLITAFILRNATWFVVQLTMNPEVHESNVVWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDKLRKWMFICIGWCIPFPIIVAWAIGKLYYDNEKCWFGKRAGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLSLLGITYMLFFVNPGEDEISRIVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAVRKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSSAV
What is the function of this protein?
G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin).  Has high affinity for CRH and UCN.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase.  Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.
What are the official names of this protein?
Corticotropin-releasing factor receptor 1, CRF-R-1, CRF-R1, CRFR-1, Corticotropin-releasing hormone receptor 1, CRH-R-1, CRH-R1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
Protein: ATP8_MAMPR
Sequence: MERMDIIIWLLAVVIVLTTLMIFLHLKTLKIIRLLFPVSKELSKKSCVFPWKKKWTKNYPPSSMYP
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: SEPF_LISW6
Sequence: MGLSNKFKSFFFLDEEEEYYEEEVAREPEPMQKKTKKEKPSKNRFYAVEEEDAKVVSMQGAQYSSRMVLAEPRVYAEAQELADYLKDYKTVVVNLQRISHDQATRIVDFLSGTVYALGGDIQRVGNNIFLCTPDNVEVNGSISEMLDEQNFM
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: SYL_CLOPE
Sequence: MGNYSTAIDKKWQDKWAESGLYKFDPNKEGEKLYVLEMFSYPSGSQLHAGHWFNYGPVDSWARFKRMQGYNVFQPMGFDAFGLPAENFAIKTGIHPQDSTIKNIAKMEEQLKAMGAMFNWENEVVTCSPEYYKWTQWLFLKLYEKGLAYRKKAPVNWCPSCQTVLANEQVVDGACERCSTEVTKKDLTQWFFKITDYADELLDKLDGLDWPEKTVSMQKHWIGRSTGSQVNFKVKDSDLNFDVFTTRVDTLCGVSYVVLAPENPLVDEIVSAEQKEAVENYKEEAKKQSDIERQSISREKTGVFTGAYAIHPLTGKEVPIWVGDYVLATYGTGAVMAVPAHDERDFAFAEKFNLPINRVIEAKDGSETNLPFCEHGILVNSGEFDGLTTDEAKEKIVEKLSSMGLGEKKVNFRLRDWLVSRQRYWGAPIPVVYCEECGIVPVPESQLPVELPYDVEFAPDGKSPLAKSEAFVNTTCPHCGKPAKRETDTLDTFVCSSWYYLRYPDNKNTEAPFNPELINKMLPVDKYVGGPEHACMHLLYARFITKALRDMGYLNFDEPFTSLTHQGLILGPDGLKMSKSKGNTISPDDYIKEYGADVFRMYLMFGFAYTEGGAWSDDGIKSVNRFVERIERIIDTAREAISKGENNKTTMDKAEKELNYWRHNTIKSVTDDTDKLQFNTAIARMMEFINALSKYTQEKEMNLDFLKDVVSDYLRLLAPFAPHFSEEQWNLLGNSYSIFNEAWPKFDPKALVKDEVEIAIQVNGKIKNKIMVSSDLDEEGIKAAALADEKIIASTEGKTVVKVIVIKGRLVNIVVK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPIL2_EMENI
Sequence: MGKGTDKLYITHSEWASEDAYSASAGAGVGKARRGVGEASFKRLPFRFCSLSLQPFEHPVCTQSGTIFDLTSILPWIKKHGTNPVDGTPLKGSDLIKLTIAKNDAGEYIDPVTYKVLTDNTHVVALRNTGNVFAWDTIERLNIKGKMWRDLVSDEEFTRKDIITLQDPQNIESRDLSRFNHIKEGESGLSDEQLREREDPSRNVNVNALGSSAKILKAREAVAKARQERAQKAGNAASTPVAKTDAPVKSAQKTASYQSGKPVPYNAARYTTGLAAASFTSTGMTPHTSAELALLSDEDYMLKRGRVKQKGYARISTTSGDINLELHTEYAPKAVWNFIKLAKKGYYKDVTFHRNIKGFMIQGGDPTGTGRGGESIWGKYFNDEFEGPLKHDSRGTLSMANKGKNTNSSQFFIAYRALPHLNLKHTIFGHVIDDPTPSSPTLNKLETHPVNPTTNRPTPDIRIVDVTIFVDPFEEFLKQKKQSEQSAENEANRTAENDEEGSRRAEDDQITWTGKRVRGPGASKEESSTTVGKYLKAALSERAAHDEDEIVEFVDEEPTSEPAKKKFKGIGGFGDFSSWD
What is the function of this protein?
May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins.  May also function as a chaperone, playing a role in intracellular transport of proteins.  May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on proteins.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase-like 2, PPIase, Cyclophilin-60, Cyclophilin-like protein Cyp-60, RING-type E3 ubiquitin transferase isomerase-like 2, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SLAP_NIACI
Sequence: MKSLLRKWNGMMIIALVISLLTPAWGKASAQSLGQESGGVQPQSAGVTDDVYVLSRDGTFRLPVGHINVNVDAPPQKTNYVALFTSGAQVTNSQETDKVFVKKTNTAIAVDKHDQVIRVIGPTAVPPTGSTWEENQNLPIPEGGYVLLANDSSWGTSVTRKPLFEHYKTGDTVSLHKGGQVVHAGDFLNPDPGLNLVTASGTTVTSPDFTVSGQVVRYGSGQGISLTVNGTEAALKADGAFQSAVRLTAGTNAISVKLLKDGREIVSSTVTVTYNDAQQPADLIEVEAAPIDITISIEGPAHAIGYVDQDIAGIDDTVALFTNDWGPQITVPQFNVAVQVDAGSKVTKVVNPSIDGKTPAWTGPTDLEIPSGGYVLVAQDTSYAGKNIKKYLATYFKVGDAIKLRKNGFAVPVKDLMGTGGPIARVTLDNYAMYTETKPSTELSGTITNMDDPSKIALTVNGTPLPFGPDGKFKTSYTLAEGINYLDLVVTKEGKEQDSKDLVVYSRPGFSTGKKVILWVDQAANARKFQTGDNVANFLRTAKENGVTSVVFDVKGVEGYVSYKKSTLTGRPYVSAIKAPEKAGSNPDLDLLQEFIRYSRELGLDIHVSFNIFAEGSIASNEFALLDSHLDWEERVYNAADNGQIKRLRESAKQGAVAFVNPSNDEVRDFQLKTIEEVLQNYDVDGVVLDRARYDNESADFSDLTKAKFESFLGARGKQLQNWPDDVFTYAGNVRKDGPLIRDWWEFRSKTIKSFTSEVRQLTDRVKAEKGKKIEVSAYVGSWFESYYLNGVHWGSTEFRYDERLRMKDKSVYTPGYYESGYVKNLDFIMIGAYQTTAPEIEHYITLGNIVTNGEVPLYAGIALTNVQEPALQRDVFQAGLVNTHGLMLFDASQVNWPVAGAALRNLVYVRDYQLGISLPDSPDSFLEGSYYNTNLIENNIGVLTDTFGYSTGNSRFGVEAVVDSSGKVTSVPNKTQAMTWNWGKPDETNSVIPKGGFVVSTLDASGIRTKRQLVANAYETGDSVRAAALSGFLAYEGLRTSADSVTFRGKVDVLGPGKASVTVNGQEAALREDGTFQADTVIRPGANPVVIIVRVDGFKTNEKTVTIIGDEAAVKALKLDRGTYSMNKGESLRLAVTAEYSSSSTDVTGQAAYASLDPAVVSVDATGRITALREGSGTVQATYEGHTATARVSVTSGSTGGGSDTGSGTGSGSGGGSAGGGGTAPSGPERTSVTETKDSDGRNLTLVSADAGVMEAEIAALQGKAAPVLSYEIPGEEPAGIVSLPGTALAKRFAGSPGAILSVSSHLGAIELPAGLLEADLPAVGSFDLLVQIGRTAADETADLRPGGERRHAGTRHAGCFPCFAENRRRNKRNRRLRKLRPKNRKLAGSGRPLTAPRRWSWTRPPECSASCPPASNRPGARRRPLSATEAGGPTRWSPPRSASPTLHPTGRARMSSCWPRSIVDGMGAGGFSPDEALTRAQFAALLTRALALDPAPAAADFTDIPGDAWYAGAVARRSGPARGRFRNRGVPTRRGADTRTDERDAHARREAGRYPDGGELRCRCAGALRGPGRNLRLGGRCRFAGGGSRPAGRTRGRTLRARPARLPVRKARPC
What is the function of this protein?
The S-layer is a paracrystalline mono-layered assembly of proteins which coats the surface of bacteria.  May play a role in the export of butirosin from the organism.
What are the official names of this protein?
S-layer-related protein.
What are the subcellular locations of this protein?
Secreted, cell wall, S-layer. Note=This bacterium is covered by a S-layer with hexagonal symmetry.
Protein: DAPA_ESCF3
Sequence: MFTGSIVALVTPMDDKGNVCRSSLKKLIDYHVASGTSAIVSVGTTGESATLSHDEHGDVVMMTLELADGRIPVIAGTGANATAEAISLTQRFNDSGVVGCLTVTPYYNRPTQEGLYQHFKAIAEHTDLPQILYNVPSRTGCDMLPETVGRLAKVKNIVAIKEATGNLSRVHQIKELVSDDFLLLSGDDATGLDFMQLGGHGVISVTANVAARDMAEMCRLAAEGQFAEARVINQRLMPLHNKLFVEPNPIPVKWACKELGLVATDTLRLPMTPITDNGKEIVRAALKHAGLL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_MAGSA
Sequence: MASDAKFRRVLLKISGEGLMGTREYGLDPETVDRIAREVKSVRDLGVEVCVVIGGGNIFRGVSGASSGMERAAADNMGMLATVINALSVQNALEKVGVETRVQSAIVMPTVCEAFIRRRAIRHLEKGRVVIFAAGTGNPFFTTDTAAALRAVEMGCDALLKATQVDGVYSADPKKVKDAVRYDRLTFNEVLARDLAVMDTSAIALCRENKVPIVVFDLHRPGAFAETVSGRGLFTIIAND
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMPS2_MYCTU
Sequence: MISVSGAVKRMWLLLAIVVVAVVGGLGIYRLHSIFGVHEQPTVMVKPDFDVPLFNPKRVTYEVFGPAKTAKIAYLDPDARVHRLDSVSLPWSVTVETTLPAVSVNLMAQSNADVISCRIIVNGAVKDERSETSPRALTSCQVSSG
What are the official names of this protein?
Probable transport accessory protein MmpS2.
What is the protein family that this protein belongs to?
Belongs to the MmpS family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: YGIQ_SALTI
Sequence: MSAISLIQPDRDLFSWPQYWAACFGPAPFLPMSREEMDQLGWDSCDIILVTGDAYVDHPSFGMAICGRMLEAQGFRVGIIAQPDWNSKDDFMRLGKPNLFFGVTAGNMDSMINRYTADRKLRHDDAYTPDNVAGKRPDRATLVYTQRCKEAWKDVPVILGGIEASLRRTAHYDYWSDTVRRSVLVDSKADMLMFGNGERPLVEVAHRLAMGETIDQIRDVRNTAIMVKEALPGWSGVDSTRLDTPGKIDPIPHPYGEDLPCADNKPVAPKKQEAKAITVQPPRPKPWEKTYILLPSFEKVKGDKVLYAHASRILHHETNPGCARALMQKHGDRYVWINPPAIPLSTEEMDSVFALPYQRVPHPAYGNARIPAYEMIRFSINIMRGCFGGCSFCSITEHEGRIIQSRSEDSIINEIEAIRDTVPGFTGVISDLGGPTANMYMLRCKSPRAEQTCRRLSCVYPDICPHMDTDHTPTINLYRRARELKGIKKILIASGVRYDIAVEDPRYIKELASHHVGGYLKIAPEHTEEGPLSKMMKPGMGSYDRFKELFDLYSKQAGKEQYLIPYFISAHPGTRDEDMVNLALWLKRHRFRLDQVQNFYPSPLANSTTMYYTGKNPLGKIGYKSEDVVVPKGDRQRRLHKALLRYHDPANWPLIRQALEAMGKKHLIGGRRECLVPAPTIEEMREARRQNRNTRPALTKHTPVEHQRQGLAANKKRGKGAGR
What are the official names of this protein?
UPF0313 protein YgiQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0313 family.
Protein: RGMG_RHIL3
Sequence: MAVSPTTMAAVRASGAVPNAEYLLSAEGVRKEFPGVVALDDVQFRLKRASVHALMGENGAGKSTLMKILAGIYTPDKGDIRLKGIEIQLKSPLDALENGIAMIHQELNLMPFMTVAENIWIRREPKNRLGFIDHGVMHRMTEELFTRLNIAIDPDIEVRFLSVANRQMVEIAKAVSYNSDVLIMDEPTSALTEREVEHLFRIIRDLKAQGIGIVYITHKMNELFEIADEFSVFRDGRYIGTHASTDVTRDDIIRMMVGREITQMFPKEEVPIGEVMLSVKDLCLNGVFKNVSFEVRAGEILGVAGLVGSGRSNVAETLFGVTPASSGSIELYGKPVAISSPTEAIRNRMAFLTEDRKDTGCLLILDILENMQIAVLQDRYVKGGFVQQGAVEATCEDMAKKLRVKTPNLYERVENLSGGNQQKVLIGRWLLTNPRILILDEPTRGIDVGAKAEIHRLVTEMARDGVAVVMISSEMPEVLGMSDRIMVMHEGRVTGFLNRDEATQIKVMELAAQ
What is the function of this protein?
Part of an ABC transporter complex involved in carbohydrate import.  Could be involved in ribose, galactose and/or methyl galactoside import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Putative ribose/galactose/methyl galactoside import ATP-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Carbohydrate importer 2 (CUT2) (TC 3.A.1.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.