PharMolix/UniProtQA huggingface dataset:
Protein: MURB_ROSDO
Sequence: MSEMPKVRGRLTQARPLSDLTWLRVGGPADWLFQPADVEDLSDFLARLPEEVAVFPMGVGSNLIVRDGGLRCVVIRLGRGFNQIDISGTRVVAGAAALDAHVARKAADAGLDLTFLRTIPGSIGGAVRMNAGCYGSYTADVLVEVQVVSRTGEVTTLAARDLQLGYRHSTLAEGAVLTKAVFEAPRGDPETLHARMTDQLARRDATQPTKERSAGSTFRNPAGFSSTGRSDDVHDLKAWKVIDDAGMRGARRGGAQMSEMHSNFMVNTGRATAADLEGLGEEVRKKVYDSSGITLEWEIMRVGEKLSSD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3NO2_OPHHA
Sequence: LTLVVVTIVCLDLGYTLTCLICPEEYCKRIHTCRDGENVCFKGFYEGKQLGKQFRRGCAATCPEGKPNEIVQCCSTDECNH
What is the function of this protein?
Binds with low affinity to muscular (alpha-1-beta-1-delta-epsilon/CHRNA1-CHRNB1-CHRND-CHRNE) and very low affinity to neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR).
What are the official names of this protein?
Weak neurotoxin OH-72.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Ancestral subfamily. Orphan group II sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: THIE_CROS8
Sequence: MTPLFAPVPHRLGLYPVVDSVEWVTRLLDAGVRTLQLRIKDKTDAEVETDIAAAIALGQRYHARLFINDYWRLAIKHQAYGVHLGQEDLETADPDAIRRAGLRLGVSTHDDMEIDVALAVRPSYIALGHVFPTQTKQMPSAPQGLAQLAAHVKRLGDYPTVAIGGISLERAPAVLETGVGSIAVVSAITQAPDWRGATQRLLELAGVGDE
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: RK27_CHRAL
Sequence: STKNGRDSNSKRLGVKVYGNQPAKAGSIIVRQRGLTFKPGKGVSVGKDYTIFATQNGIVQFESDKKEKIISVY
What are the official names of this protein?
50S ribosomal protein L27, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRNHE_ARATH
Sequence: MDKRWSLQGMTALVTGGASGIGHAIVEELAGLGARIYVCDISETLLNQSLSEWEKKGFQVSGSICDVSSHSERETLMQTVSKMFDGKLNILVNNVGVVNPKPTIEYVAADFSFSISTNLESAYHLSQLSHPLLKASEFGSIIFISSVGGVVSMECGSIYSLTKGALNQLAKTLACEWARDGIRANSVAPNFIYTAMAQPFFKDADYEKSLVSRTPLGRAGEPNEVSSLVAFLCLPAASYITGQTICVDGGLTVNGFSYKPQA
What are the official names of this protein?
Tropinone reductase homolog At2g30670.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. SDR65C subfamily.
Protein: GAL1_CANAX
Sequence: MSVPTFDDLSFYSNDQELTKSRYLKLVEIFQSNFPNASIDFFARSPGRVNLIGDHIDYNFFPVLPMAISADVIVAVNVNDEPEIVITHTDSKNFAKETIPLTNNNDGFEIDSQHHSWANYFKCALIVANNYLTEQNLKGQLKGMKLTFDGNVPTGGGLSSSAAFCVASTLAILHANGVKDITKADLTRITVVCEHYVGVNTGGMDQCASVYGEPDKALLIQFKPKLIGKPFKFPVENLTFVITNSLQVSNKHETAPIHYNLRVVEMAIAADVLVKKLNLGTLVPQDSNIGTSSLRGVMDAVFNTCKWDGNDIDVGIDQLKKMIAIVETELNNNQEGYTVDQCLTVLDLSLDEFKSKYLQAYPVKFDVLKLYQRAKHVYQESLRVLETLKLLSTTQTSSNSKDDDESFLVKFGELMNQSQSDLDKLNESSNDKLNKICSIALQNGSYGSRITGAGWGGSIVHLTTLDKSKQLIQGLIKNYYQLEFPSIKLDELLNDAIIDSKPSMGSCIVTTKFLQ
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
Protein: RLMH_CAMC1
Sequence: MEISVFSIQKSSRDNFENEIQEYIKMSAKFAKINDKIIFNEKIARAQSSGRSDALRAYDEIYEPNLKGFCVMLDENGSQLDSQEFAQILNSNSQINFFIGGAYGLSQNLKDKAQKVVSLSKMTMAHKVAKLVLFEQIFRGLCINANHPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPCKG_METPE
Sequence: MLRLPDEHRALFRNPFGTLYPEFSMVLPHLAGRAIYTVGDVVTANILAAGILPAIAIIDGYTRRLPCPPALLHQARQILVKNPAGAITDELIAAIGDAAANPPALIVVEGEEDLAVLPVILAVPDGGFLLYGQPGEGAVLCTVDQQAKERAREMLALFEQV
What is the function of this protein?
Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
What are the official names of this protein?
GTP-dependent dephospho-CoA kinase, Dephospho-coenzyme A kinase, DPCK.
What is the protein family that this protein belongs to?
Belongs to the GTP-dependent DPCK family.
Protein: BIOH_ECOL5
Sequence: MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSRGFGALSLADMAEVVLRQAPDKAIWLGWSLGGLVASQIALTHPERVLALVTVASSPCFSARDEWPGIKPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARALKKTVLALPMPEVDVLNGGLEILKTVDLRLPLQNVSMPFLRLYGYLDGLVPRKVVPMLDKLWPHSESYIFAKAAHAPFISHPVEFHHLLVALKQRV
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UTP20_SCHPO
Sequence: MKAAAQSNSKNYVFLPFSKRVENLKIDVAHKIPRAADLEDEDVESYFISCLRKWEDLNLSTHYVNFLRSVTPYSQSLPQIVYHQKTIFDLIVQYAREGDSLSLQPILELLTQFARDLALEFASYIDQTLELLCILVQNNELEVVDWSFHAAAYLFKYLRKILAPRLIHTYDILSPLLGKEKQKSHVTRFTAEALSFLCKTVSYENAIEFTGHVLLDLNDHYTPQYHEGVVILFSRIIQGVDTSIHFKGKAFFEILLRSEIYTLPRSKSVIIPVLISTIHHCTSDSFNELEKLIISKITGEPLLYINLFKATLVTRKGSRVSDYPSFFKAYLQIPNLVSWENIESDLSVLIFEISALLFVYPQISDLMPHTVRIISFLQQGPLHLFFSFVDVVKQLNMQRYDSFIKPSLPKFISSLVSDESQKSLAILESVLDNSVPVPVDVASVSLNHFVYCIERLQIVSPSYEDIISLWSSLMIIISSSLGSDEIYKACLLFLRKLEDVSSESVLLGDICGIVLHLLQRKVSRLFLDSSYYKPILDSLLGVFGFLADSKVFLESIRPFFGTSYDFCSSYTSLMDRLINNLSRGLTSLRAASIDLIIALCKSLQKNEVLQSLSLVKKLSELPFDPSTSRDASVLLRNLSAKSSALEKDTRRVVLHALLGLTITRFTPLWPDLSRTAASIVTKEVEDEFLAIIYSWLSLPSPPSGLLGPTDTAVFVKPDLSLEKLPTLEINTFNCPAISYFETSFDECFSKFASSDNYIIGNLLKTNQEDLSNLPTFRSQALRVLNELPEIASRNINVLDNYLFSLQHGFDLNTEWARPDVYLLLGLYSKFTGIKEFVNRDARKEFFLWALTINDPKVQKLVLDIILLYSEEAITTYEENLRNLLDDKKCRDELITFLFVDYADSKIQDIHRPLLMPVVISILYGKMVSKGYGGQKNQAARRSTILSALGNMQVEDLQILVDIMLRPYNGLEVKLNANNNLEIDTGNIPSLTLRRQIGFLTMTEELLLQISSKLSSVAPKILNAVLYNLVVSDDQISSQEAFENFEVKMAYTVRQLSLKVFLLFLKSCSDVDFKPYNVFIYTAFVVPRLDRFADENTQSVSNLMKIFRCWFENEAYLDSVLEFSSHILTALLNTASHTAVKLPVLLYILDTLNLVITHLQSEESESQLREKILANLVMPNITLIFASLSNILKNPQFCNNNRVMDGSVQALSAVSEYMSLDIDSSPLLNLLVSFLRKPNRLVPSNVKSNILVLLCKLLPTNTKWLHASISQTNDFDTIMHLYTSMVDIKARQHLNDLLKIYSTIDDNLIFSSVFVEEINSISKKRLDEPDFERRLSAFTSFNEKHFSLISDLAWLPVLYNFFFYVQDAEELAIRASASLGIKRFIESITMNDASNQFKIDVFVKFIFPFIKNQMKNKNELIRQEFIGLLSYSIKSLTMVDAISDMQPLLYEGDEEANFFNNILHIQLHRRKRAMKRLVNVCAIGVIRSGNISQIFLPLLENFCLGNDTVQTLLDESVITIGEIIKWAHWNQYQAILKRYVSLLKNNAIDQKVVVRLITAVVSALRPLDDAVASYTNSEMNIEQFDGQKKKCVLASSLPSEERFTEVLTNDFFPTLMLYLHIRDESTVTLRVAIALSIVQLVALLPEEEIVLRLTPVLIDTCHILRSRSLESRDATRKALAAISKFLGPKYFSFIISQLQTSLKRGYQLHVLGYTVHYLLLAIEDVYPYGSIDYCMDSLAQIFVDEIFGEVGVEKDSEDYKSNVKEIKGNKSYDSYEIVARISSFDSLSTLLRPVKNVLFETNVPKSLRKVDELCRRLSLGIVANKQSASQSSLIFCYNVYEFVVKEKETVAALKQQENDGYRSAPNFFLENSKKLIRFTFDVLRGVSNKHKELLTARNMAAFVPLIGESLLSSSEEVQISALRFLVLLLPLKIDQVFSGSSVFTSQAVKYIQNSPSTNTELCQASFKFLASILPYENVKIKESTINYLLERVGTDIQEPDRQGVMFSLVRAVIARKIMTPELYKIIDLIRDMMVTNHTKSTRQTCRHLYYSFLLDYPQGKTRLSKQISFILKNLEYEFAPGRESVMELLHLILNNFSDALLKEYHQGIFIALVMVLANDSEPHCREMSAELIKLVYQRADNENFNLIRQLLSHWTSVEKAGKNLVRVSMQLFGLLFETFGFERMEEVHLFTKVFERVLSTTISHPEEATNEWELNYFGLQSWLKLVLADPKKSCEKEFSKIWESMRYLILFKHAWVRLSVSRLFGHFFAIIGDSNFGKLSLGIDGVVFSLDFVTQISNALQAQLRSPVLSEELGMQVAKNLIFLTRWFNSIRSSDDSPFLEIFRRMRKTLKKQTIEEYSINKKYLMQWFASVIHVFSGEELQPVLSEIIAALYRYTELQEAERKSQQELADLVTESLQVLQEKVGATVFARAYQEVRNAAIEVRRERREKRAIEQVVAPEVASRKKIRKNERKRENRKQKTNHHRMVNSIFKNR
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 20, U3 snoRNA-associated protein 20.
What is the protein family that this protein belongs to?
Belongs to the UTP20 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: TO20L_MOUSE
Sequence: MPSVRLGVGLLAGLAAGGAVVLLSYCVYLDWRRHRDPAFRRRLQDKRRAGQPKAQAPARQLWDPVKKEELQEYFFREVQMGKLCLIRGERGMGFEHLTNALLVCEQPKELLMFFKKTLPPEVFQMLLDKIPLICQQLEETCRSTEHLKDDPD
What are the official names of this protein?
TOMM20-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the Tom20 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: KLH20_XENLA
Sequence: MRRCLNTRPGETGMDVTSRCTLGDPNKLPEGVPQPARMPYVSDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFSYTSQITVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLNSVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGYLYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTIAPMGTRRKHLGCAVYQDMIYAVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVFDPDANTWRLYGGMNYRRLGGGVGVIKMTHCESHIW
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in interferon response and anterograde Golgi to endosome transport.  The BCR(KLHL20) E3 ubiquitin ligase complex mediates the ubiquitination of target proteins, leading to their degradation by the proteasome.  It also specifically mediates 'Lys-33'-linked ubiquitination (By similarity).
What are the official names of this protein?
Kelch-like protein 20.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Nucleus.
Protein: Y2440_ACIBY
Sequence: MYKDIKVDPAQLEAALDARLKIRAGFDKPTAGMAAGMTQVNMISVPRDWAYDFLLYAHRNPQSCPVLDVLEEGIYATKLAADSDIRTDFPRYRIWKDGEMVDEVTDAREIYNAHPDLVTFLIGCSFSFETALQEAGIEVRHIHDDTNVPMYLSNIKCEPAGRISGNMVVSMRPIPSHQISEAVKITARMPSVHGAPVHIGHPESLGIKDVNKPDFGDASRIEAGEIPVFWACGVTPQAAVMNSKIPFAISHAPGYMFITDIPDRAWMG
What are the official names of this protein?
Putative hydro-lyase ABAYE2440.
What is the protein family that this protein belongs to?
Belongs to the D-glutamate cyclase family.
Protein: CSPL4_HORVV
Sequence: MGSFANGQNGSELGIQTPATGSNAALEPPTTSAAAPRCPRLGMAMVAARAAALVMALLSVSLMVSAKQRGTLAIFGIEIPLYAKWSLSDSLQSLVGISAAAAAYSLAQLLSIAHTALKKAPVVPSRRYAWMLLAGDQVFAYAMLSAGSAAAAVANLNRTGVRHTALPNFCKPLPRFCDLSAASIACAFLGCAFLAASAVIDVIWLSRL
What are the official names of this protein?
CASP-like protein 3A1, HvCASPL3A1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACY2_MOUSE
Sequence: MTSCVAKEPIKKIAIFGGTHGNELTGVFLVTHWLRNGTEVHRAGLDVKPFITNPRAVEKCTRYIDCDLNRVFDLENLSKEMSEDLPYEVRRAQEINHLFGPKNSDDAYDLVFDLHNTTSNMGCTLILEDSRNDFLIQMFHYIKTCMAPLPCSVYLIEHPSLKYATTRSIAKYPVGIEVGPQPHGVLRADILDQMRKMIKHALDFIQHFNEGKEFPPCSIDVYKIMEKVDYPRNESGDMAAVIHPNLQDQDWKPLHPGDPVFVSLDGKVIPLGGDCTVYPVFVNEAAYYEKKEAFAKTTKLTLSAKSIRSTLH
What is the function of this protein?
Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate.  NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter (By similarity).
What are the official names of this protein?
Aspartoacylase, Aminoacylase-2, ACY-2.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Aspartoacylase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HIS3_CORJK
Sequence: MSNTDSKTGPNTDPATCELDPAIAERVRFNADGLVPAIVQDITNGDVLMMAWMNDHALAHTLATKKGTYWSRSRQSYWIKGETSGHTQRVEEVRLDCDGDTVLLKIEQTGAACHTGNRTCFDADRLA
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_GLUDA
Sequence: MMFHVKPQGGNGVPDALRAKLDRFAEILTRWNSRINLVSPRDLAHLWDRHIADCLQLASLIPPGVRLADMGSGGGFPGLIIAMATDADVTLIESDQRKAAFLREAARAVGARVTIIARRIEDADIPPVQVVTARALAALPQLLEWSSHFLAPDGFCLFLKGRNVEDELTAAAADWHMAVSRLPSRTNADGTILRLGDIRRVRHSERAPGR
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TKN1_PHLMA
Sequence: DEPKPDQFVGLM
What is the function of this protein?
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
What are the official names of this protein?
Hylambates kassinin, [Glu2,Pro5]-kassinin.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: C_NIPAV
Sequence: MMASILLTLFRRTKKKYRRHTDDQVFNNPASKIKQKPGKIFCSAPVENLNKLRGECLRMMEMLKEETWRIYPVLLPQMELLERECRTPVTGQKVQMTYNWTQWLQTLYTMIMEENVPDMDLLQALREGGVITHQEQTMGMYVLYLMQRCCPMLPKLQFLKKIGKLI
What is the function of this protein?
May counteract the cellular interferon antiviral system.
What are the official names of this protein?
Protein C.
Protein: XYNC_ASPCL
Sequence: MVVLSKIFSCALFLSLGSAAAIDIRQTSSINNAFKSHGKKYFGTCGDQNTLSIPQNSAIIKADFGALTPENSMKWDATEPSRGKFNFAGADHLVNYAKQNGKLVRGHTLVWYSQLPAWVKAISDKQTLTSVLKNHITTVMSRYKGQVYAWDVVNEIFEENGSLRNSVFYRVLGEDFVRIAFETARAVDPHAKLYINDYNLDSANYGKTQAMVKHVKKWLAAGIPIDGIGSQSHLSQALSALASTGVSEIAITELDIKGANPSEYVAVTKACLEVKKCIGITVWGVSDKNSWRKDNSPLLFDRNYNPKPAYNAIIAAL
What is the function of this protein?
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Probable endo-1,4-beta-xylanase C, Xylanase C, 1,4-beta-D-xylan xylanohydrolase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 10 (cellulase F) family.
What are the subcellular locations of this protein?
Secreted.
Protein: EFG_STRTD
Sequence: MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWNGHRVNIIDTPGHVDFTIEVQRSLRVLDGAVTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAHPIQLPIGAEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYVDQANEYREKLIEAVAETDEDLMMKYLEGEEITNDELKAAIRRATINVEFFPVLCGSAFKNKGVQLMLDAVIDYLPSPLDIPAIKGINPDTGEEETRPASDEAPFAALAFKIMTDPFVGRLTFIRVYSGILQSGSYVMNTSKGKRERIGRILQMHANSRQEIEQVYAGDIAAAIGLKDTTTGDSLTDEKAKVILESIEVPEPVIQLMVEPKTKADQDKMAIGLQKLAEEDPTFRVETNPETGETVISGMGELHLDVLVDRLKREHKVEANVGAPQVSYRETFRAATQARGFFKRQSGGKGQFGDVWIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLEESMANGVLAGYPMVDIKAKLYDGSYHDVDSSETAFKIAASLALKEAAKTAQPTILEPMMLVTITVPEENLGDVMGHVTARRGRVDGMEAHGNTQIVRAYVPLAEMFGYATTLRSATQGRGTFMMVFDHYEDVPKSVQEEIIKKNSGEA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRD2_MELGA
Sequence: MDPLNLSWYNTGDRNWSEPVNESSADQKPQYNYYAVLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWRFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAAAMPMLYNTRYSSKRRVTVMIACVWVLSFAISSPILFGLNKADERECIIANPAFVVYSSVVSFYVPFIVTLLVYVQIYMVLRRRRKRHTKRSSHGLDSDTHAPLKDKCTHPENVKLGTVIVKSNGSFQVNKRKCEAESHIKMEMEMMSSTSPPERTIVKAAAPSNHQLVVPVASSRSTLDSPGKVEKNGHAKENLHTAKVFEIQSMPNGKTRSTLLKAMNRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNMHCDCNIPPAMYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
What is the function of this protein?
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase (By similarity).  Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5 (By similarity).
What are the official names of this protein?
D(2) dopamine receptor, Dopamine D2 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: Y3450_ACISJ
Sequence: MPLKDLPLDAQPREKLLARGPAALSDAELLAILLRTGLAGKGVLQLAQELLDDPVRDSATGRSAGGGFGGIAGLLHASSQDLQRIKGLGPAKRAELMAVLELARRALAQQLREREVFDSPQAVQHYLQLHLAGRTHEVFAVLFLDSGNRLIAMEELFRGTLTQTSVYPREVVLRALHHHAAAVVLAHNHPSGSVQPSRADEALTQTLKAALALVDVRVLDHVIVAPGAALSMAEQGLV
What are the official names of this protein?
UPF0758 protein Ajs_3450.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: SECA_GEOUR
Sequence: MFGALIKKIVGSKNERELRRLWPIVEQINHLEAEISSLSDDQLRNKTTEFKERYARGETLDSLLPEAFAVCREAGKRVLGMRHFDVQLIGGMVLHQGKIAEMKTGEGKTLVATLPSYLNALTGRGVHVITVNDYLARRDSEWMGRIHSFLGLSVGVIIHGLDDDERREAYNADITYGTNNEFGFDYLRDNMKFSLDDYVQRDFHYSIVDEVDSILIDEARTPLIISGPTEDSTDKYYIIDRIIPLLKKGEVLEEEANTLSGKRKRYTGDFTVDEKSKSATLTEEGVLKVEKLLKVDNLYDPRNMETLHHVNQALRAHALFKLDVDYVVKEGEVLIVDEFTGRLMPGRRWSDGLHQAIEAKEGVKIENENQTLATITFQNYFRMYEKLSGMTGTADTEAEEFHKIYKLDVVVIPTNRVLLRPDFPDVIYKTEGEKFNAVIEEIRELHAKGQPVLVGTISIEKSEVLSELLKRQGIPHNVLNAKQHEREAEIVAQGGRKGMITIATNMAGRGTDILLGGNADAMAKQWRRGNPEASDGEYERVLAQFKEQCANEHDEVVKLGGLHILGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLQDDLLRIFGSERVAKIMDMLKIEEGEAITHGLITKAIENAQRKVEAHNFEIRKHLIEYDDVMNKQREVIYAQRREILAGEGIRESFLDMVDETVADLAAGYAIDKVPAQEWDWQGMGDSIYKIFGFQVDIPAETMERLNPFNLRELLQEKVRELYTAKVAEFGDELMDHLIKVIMLQSIDTQWKDHLLSIDHLKEGIGLRGYGQKDPKQEYKKEAYQLFMDMMLRTREEVVEKIFWVQIAREEDVEKMEEQQKRQRLVFNLGDEPEAQQPVTSKKVGRNEPCPCGSGKKYKQCCGK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: ATPB_SYNFM
Sequence: MNLGKIVQVIGNVVDVEFGEGKLPPLLTALFVSNPGLNDQEDNLVLEVAQHLGDNVVRTIGMDLTDGLVRGMPVKDTGNPIMMPVGAAVLGRVINVVGRTVDGLGPVNTDTYMPIHRTAPAFTEQDTSVKVLETGVKVIDLLVPFPRGGKMGMFGGAGVGKTVVMMEMIHNIAMQHGGISVFAGVGERTREGNDLYHEMKDSGVLPRAGLVYGQMTEPPGARARVALSALTVAEYFRDVEGQDVLLFVDNIFRFTQAGAEVSALLGRMPSAVGYQPTLGTDLGELQERITSTTKGSITSVQCVYVPADDLTDPAPATTFAHLDGTVVLSRQIAELGIYPAVDPLDSTSRILDPNVLGEDHYYTAREVQQILQKYKDLQDIIAILGMDELSDEDKLTVARARKIQRFLSQPFHVAETFTGVAGKYVKVEDTVRGFKEICEGKHDDIPEQAFFMAGGIEEVLEKAKQMSAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SPSS_METMA
Sequence: MTLDDSSLQKFGFIKRETLGSINIDPLQTGGLLTGAAKQALVEWGDGYSVCDFCGGVLDLVKKPPIHDFVHKALPEFLGCDEARVTNGARESKFAVMHSMGKPGDWVVLDGLAHYSSYVAAERAGLNIEVVPHAGSPEYHLDPGRYGKAIEEVTKENGKPPVLALVTYPDGSYGNIPDAAKIASVCHEYDVPLLLNGAYSVGRMPVSAKEIGADFIVGSGHKSMAASGPVGVLGVSEEYAPVVFRKSVHNKVKEIELLGCTARGATVMTLMASFPEVVKRTRNWDQEVENARWFSSRLEGMGFIQRGQKPHSHDLMFFEAPGFYEISQKVKNGRYFLYRELKERNIHGIKSGLTKYFKLSTFGLGKEKLGTVADAFEDILKKYENI
What is the function of this protein?
Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)).
What are the official names of this protein?
O-phospho-L-seryl-tRNA:Cys-tRNA synthase, Sep-tRNA:Cys-tRNA synthase, SepCysS.
What is the protein family that this protein belongs to?
Belongs to the SepCysS family.
Protein: XDH_DROME
Sequence: MSNSVLVFFVNGKKVTEVSPDPECTLLTFLREKLRLCGTKLGCAEGGCGACTVMVSRLDRRANKIRHLAVNACLTPVCSMHGCAVTTVEGIGSTKTRLHPVQERLAKAHGSQCGFCTPGIVMSMYALLRNAEQPSMRDLEVAFQGNLCRCTGYRPILEGYKTFTKEFACGMGEKCCKVSGKGCGTDAETDDKLFERSEFQPLDPSQEPIFPPELQLSDAFDSQSLIFSSDRVTWYRPTNLEELLQLKAKHPAAKLVVGNTEVGVEVKFKHFLYPHLINPTQVKELLEIKENQDGIYFGAAVSLMEIDALLRQRIEQLPESETRLFQCTVDMLHYFAGKQIRNVACLGGNIMTGSPISDMNPVLSAAGAQLEVASFVDGKLQKRSVHMGTGFFTGYRRNVIEAHEVLLGIHFRKTTPDQYIVAFKQARRRDDDIAIVNAAINVRFEEKSNIVAEISMAFGGMAPTTVLAPRTSQLMVGQEWSHQLVERVAESLCTELPLAASAPGGMIAYRRALVVSLFFKAYLAISLKLSKSGITSSDALPSEERSGAETFHTPVLKSAQLFERVCSDQPICDPIGRPKVHAAALKQATGEAIYTDDIPRMDGEVYLAFVLSTKPRAKITKLDASEALALDGVHQFFCYKDLTEHENEVGPVFHDEHVFAAGEVHCYGQIVGAIAADNKALAQRAARLVKVEYEELSPVIVTIEQAIEHKSYFPDYPRFVTKGNVEEALAQADHTFEGTCRMGGQEHFYLETHAALAVPRDSDELELFCSTQHPSEVQKLVAHVTALPAHRVVCRAKRLGGGFGGKESRGISVALPVALAAYRMGRPVRCMLDRDEDMLITGTRHPFLFKYKVGFTKEGLITACDIECYNNAGWSMDLSFSVLERAMFHFENCYRIPNVRVGGWVCKTNLPSNTAFRGFGGPQGMYAGEHIIRDVARIVGRDVVDVMRLNFYKTGDYTHYHQQLEHFPIERCLEDCLKQSRYDEKRQEIARFNRENRWRKRGMAVVPTKYGIAFGVMHLNQAGSLINIYGDGSVLLSHGGVEIGQGLNTKMIQCAARALGIPSELIHISETATDKVPNTSPTAASVGSDLNGMAVLDACEKLNKRLAPIKEALPGGTWKEWINKAYFDRVSLSATGFYAMPGIGYHPETNPNARTYSYYTNGVGVTVVEIDCLTGDHQVLSTDIVMDIGSSLNPAIDIGQIEGAFMQGYGLFTLEELMYSPQGMLYSRGPGMYKLPGFADIPGEFNVSLLTGAPNPRAVYSSKAVGEPPLFIGSSAFFAIKEAIAAAREDQGLSGDFPLEAPSTSARIRIACQDKFTELLEIPEPGSFTPWNIVP
What is the function of this protein?
Key enzyme in purine degradation.  Catalyzes the oxidation of hypoxanthine to xanthine.  Catalyzes the oxidation of xanthine to uric acid (By similarity).
What are the official names of this protein?
Xanthine dehydrogenase, XD, Protein rosy locus.
What is the protein family that this protein belongs to?
Belongs to the xanthine dehydrogenase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: DEOD_MYCPN
Sequence: MTPHINAKKDDIAKVVLMPGDPLRAKWIAEQFMEKPRLVNEVRGMLAFTGQYKGKTITIMGHGMGIPSIGIYSYELMKFYEVNTIIRIGSCGALQGSLNLQDLIIAAKAWSESIYANDMGVEVPADKILMASPQLVELAKKTANQLQLAFHEGLVFCEDAFHQIRKDVLKLAQEKHALAVEMEAHALYANAMLLNKQALTMLTVSDSLVTHAALPAEQRQATFKNMAILSLEMASQLV
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.