PharMolix/UniProtQA huggingface dataset:
Protein: CYB_SETPI
Sequence: MALNLRKNHQILKIINDALIDLPTPSNISTWWNFGSLLGICLITQIVTGLLLAMHYTADTNLAFSSVAHMCRDVQFGWLIRNLHANGASFFFICIYLHIGRGLYYGSYLNKETWNIGVILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFVIVGLTLVHLTFLHETGSNNPLGIPSDCDKIPFHPYYTIKDILGFVLMLSLLVSLALFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASILVLFLTPLLHTSKLRSMTFRPLSQILFWTLVANVLILTWVGSQPVEHPFIIIGQLASFSYFTIILILFPLAAALENKLLKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: UFD1_MOUSE
Sequence: MFSFNMFDHPIPRVFQNRFSTQYRCFSVSMLAGPNDRSDVEKGGKIIMPPSALDQLSRLNITYPMLFKLTNKNSDRMTHCGVLEFVADEGICYLPHWMMQNLLLEEGGLVQVESVNLQVATYSKFQPQSPDFLDITNPKAVLENALRNFACLTTGDVIAINYNEKIYELRVMETKPDKAVSIIECDMNVDFDAPLGYKEPERPVQHEESIEGEADHSGYAGEVGFRAFSGSGNRLDGKKKGVEPSPSPIKPGDIKRGIPNYEFKLGKITFIRNSRPLVKKVEEDEAGGRFIAFSGEGQSLRKKGRKP
What is the function of this protein?
Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins.  The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome.  The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope.  It may be involved in the development of some ectoderm-derived structures (By similarity).  Acts as a negative regulator of type I interferon production via the complex formed with VCP and NPLOC4, which binds to RIGI and recruits RNF125 to promote ubiquitination and degradation of RIGI (By similarity).
What are the official names of this protein?
Ubiquitin recognition factor in ER-associated degradation protein 1, Ubiquitin fusion degradation protein 1 homolog, UB fusion protein 1.
What is the protein family that this protein belongs to?
Belongs to the UFD1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.
Protein: PTTG_MOUSE
Sequence: MAPANLGLTPHWVMLLGAVLLLLLSGASAQEPPRVGCSEYTNRSCEECLRNVSCLWCNENKACMDYPVRKILPPASLCKLSSARWGVCWVNFEALIITMSVLGGSVLLGITVCCCYCCRRKKSRKPDKSDERAMREQEERRVRQEERRAEMKSRHDEIRKKYGLFKEQNPYEKF
What is the function of this protein?
May facilitate PTTG1 nuclear translocation.
What are the official names of this protein?
Pituitary tumor-transforming gene 1 protein-interacting protein, Pituitary tumor-transforming gene protein-binding factor, PBF, PTTG-binding factor.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cytoplasm. Nucleus. Note=May be cytoplasmic and nuclear.
Protein: PANB1_PSEE4
Sequence: MSTLHHRLTITDLAALKGRQKIAALTAYSTPIARLIDPLVDFILVGDSTAMVAYGRPSTLAMRLDETISHTRAVVDCTRHACVIADMPFGSYQASPEQAFRNCAQVLSETGCDAVKLESNRALAPTVAFLVERGIPVMAHVGLMPQFVHVMGGYKAQGLTEASAETIVEDARANLAAGAFSLLLEGVAEPLARRISQQSQQPCIGIGASPACDGQILVTEDLLGLGGPQQPRFVKQYADLTAVIGEACARYASEVRQGEFPELAHCYGS
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase 1, Ketopantoate hydroxymethyltransferase 1, KPHMT 1.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABI_STAA8
Sequence: MLNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISASPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK
What is the function of this protein?
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).  It has a preference for a long chain (C12) substrate compared to the shorter (C4) acyl group.  Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI, ENR, NADPH-dependent enoyl-ACP reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Protein: CEP68_PONAB
Sequence: MALGEEKAEAEASEDTKAQSYGRGSCGERELDTPGPMSGEQPPRLEAEGGLTSPVWGAEGIPAPTCWIGTDPGGPSRAHQPQASDASREPVAERSEPALSGLPPATMGSGDLLLSRESQVEKTKLSASEELPQTPSLPRTTTICSGHDADTEDDPSLADLPQAPSSGLSCLSQWKSMPSPGSAAPQPSSCSVSASSTGSSLQGHQERTEPRGGSLAKVSSSLELVVPQEPSSVVGLGPRPQWSPQPVFSGGDASGLGRRRLSFQAEYWACVLPDSLPPSPDRHSPLWNPNKEYEDLLDYTYPLRPGPQLPKHLDSRVPADPVLQDSGVDLDSFSVSPASTLKSPTNVFPNCPPAEATALPLSGPREPSLKQWPSGVPQKQGGMGLASWSQLTSTPRAPGSRDARWECREPALRGAKDWLPIGKPLDMGSPQLRTRDRGWPSPRPEREKRTSQSARRPTCTESRWKSEEEVESDDEYLALPARLTQVSSLVSYIGSISTLVTLPAGDIKGQSPLEVSDTDGPASLPSSSSQSQLPPGAALRGSGDPEGQNPCFLRSFVRAQDSAGEGSLGSSQALGVSSGLLKTRPSLPARLDRWPFSDPDAEGQLPRKGGEQGKESLVQCVKTFCCQLEELICWLYNVADVTDHGTAARSNLTSLKSSLQLYRQFKKDIDEHQSLTESVLQKGEILLQCLLENTPVLEDVLGRIAKQSGELESHADRLYDSILASLDMLAGCTLIPDKKPMAAMERPREGV
What is the function of this protein?
Involved in maintenance of centrosome cohesion, probably as part of a linker structure which prevents centrosome splitting.  Required for localization of CDK5RAP2 to the centrosome during interphase.  Contributes to CROCC/rootletin filament formation.
What are the official names of this protein?
Centrosomal protein of 68 kDa, Cep68.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes to thin fibers protruding away from the proximal ends of the two centrioles. Dissociates from interphase centrosomes at the onset of mitosis.
Protein: DCD_THESM
Sequence: MILPDHKIRKEILIEPFNEKSLQPAGYDLRVGKEAMVNGKFINVEEEGKLVIPPKGHALILTLERVKLPDDVMGDMRLRSTFAREGLLGSFAWVDPGWDGNLTLAFFNSSEEEVILHYEERFVQIAFHRLEEPSKNPYRGIYQGSQHLKLSKRKIR
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: ENO_CHLTR
Sequence: MFDVVISDIEAREILDSRGYPTLCVKVITNTGTFGEACVPSGASTGIKEALELRDKDPKRYQGKGVLQAISNVEKVLMPALQGFSVFDQITADAIMIDADGTPNKEKLGANAILGVSLALAKAAANTLQRPLYRYLGGSFSHVLPCPMMNLINGGMHATNGLQFQEFMIRPISAPSLTEAVRMGAEVFNALKKILQNRQLATGVGDEGGFAPNLASNAEALDLLLTAIETAGFTPREDISLALDCAASSFYNTQDKTYDGKSYADQVGILAELCEHYPIDSIEDGLAEEDFEGWKLLSETLGDRVQLVGDDLFVTNSALIAEGIAQGLANAVLIKPNQIGTLTETAEAIRLATIQGYATILSHRSGETEDTTIADLAVAFNTGQIKTGSLSRSERIAKYNRLMAIEEEMGPEALFQDSNPFSKA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: LIMS1_HUMAN
Sequence: MANALASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEKFPLELKKRLKKLAETLGRK
What is the function of this protein?
Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors.  Involved in the regulation of cell survival, cell proliferation and cell differentiation.
What are the official names of this protein?
LIM and senescent cell antigen-like-containing domain protein 1, Particularly interesting new Cys-His protein 1, PINCH-1, Renal carcinoma antigen NY-REN-48.
What are the subcellular locations of this protein?
Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TERD_SERMA
Sequence: MSVSLSKGGNVSLSKAAPSMKNVLVGLGWDARSTDGQDFDLDASAFLLASNGKVRGDSDFIFYNNLTSSDGSVTHTGDNRTGEGDGDDESLKIKLDAVPSEVDKIIFVVTIHDAQARRQSFGQVSGAFIRLVNDDNQTEVARYDLTEDASTETAMLFGELYRHNGEWKFRAVGQGYAGGLASVCAQYGINAS
What is the function of this protein?
Not known; seems to contribute to the tellurium resistance (Ter) mechanism.  Also involved in phage inhibition (Phi) and colicin resistance (PacB).
What are the official names of this protein?
Tellurium resistance protein TerD.
What is the protein family that this protein belongs to?
Belongs to the CAPAB/TerDEXZ family.
Protein: MSCL_PSEA7
Sequence: MGLLSEFKAFAVKGNVVDMAVGIIIGAAFGKIVSSFVGDVIMPPIGLLIGGVDFSDLAITLKAAEGDVPAVVLAYGKFIQTILDFVIVAFAIFMGVKAINRLKREEAVAPSEPPVPSAEETLLTEIRDLLKAQQNKP
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FABG4_MYCTU
Sequence: MAPKRSSDLFSQVVNSGPGSFLARQLGVPQPETLRRYRAGEPPLTGSLLIGGAGRVVEPLRAALEKDYDLVGNNLGGRWADSFGGLVFDATGITEPAGLKGLHEFFTPVLRNLGRCGRVVVVGGTPEAAASTNERIAQRALEGFTRSLGKELRRGATTALVYLSPDAKPAATGLESTMRFLLSAKSAYVDGQVFSVGADDSTPPADWEKPLDGKVAIVTGAARGIGATIAEVFARDGAHVVAIDVESAAENLAETASKVGGTALWLDVTADDAVDKISEHLRDHHGGKADILVNNAGITRDKLLANMDDARWDAVLAVNLLAPLRLTEGLVGNGSIGEGGRVIGLSSIAGIAGNRGQTNYATTKAGMIGITQALAPGLAAKGITINAVAPGFIETQMTAAIPLATREVGRRLNSLLQGGQPVDVAEAIAYFASPASNAVTGNVIRVCGQAMIGA
What is the function of this protein?
Catalyzes the NADH-dependent reduction of beta-ketoacyl derivatives (PubMed:19685079, PubMed:21081168, PubMed:23163771).  Can accept the beta-oxo fatty acyl group covalently linked with CoA or ACP for catalysis (PubMed:23163771).  Highly specific for NADH (PubMed:19685079, PubMed:21081168).  Could be involved in fatty acid biosynthesis (Probable).
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] reductase [NADH], Beta-ketoacyl CoA reductase, FASII-like 3-oxoacyl-thioester reductase, HMwFabG.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: MUKB_ACTP2
Sequence: MTDTNELFEDQTTALQNSAPIAPLANPQHTVSRGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTMAGFVTALIPDLTLLNFRNTTEAGSTSSSRDKGLYGKLKAGVCYAVLESLNSRGQRVITGVRLQQVAGRDKKVDIRSFSLQNVPMSDSIISILTEQVGEKARVLPLADLKDKFDGSEVLFKQYHSITDYHSFMFDLGVIPKRLRSSADRSKFYKLIEASLYGGISSVITKSLRDYLLPENTGVRQAFQDMESALRENRMTLEAIKVTQSDRDMFKRLITESTNYVSADYMRNANERRGNVQIALEQRRAWYESKSKLELEQQRLIEFSREVADISENESSLEAEYNSANDHLNLVMNALRHQEKIERYQNEVAELNEKLEEQQIALEEVSEQVETAQARADDADDQVEELRSQMADYQQALDAQQTRALQYQQAIAALEKAKQLCGLPHLDLHNVEDYHAEFAAQADDLTDQVFELEQRLSVSDMAKTQFEKAYELVCKISGEIDRSEAWNEARSLLTAFTDQKMQATQAVALRQKLADLEQRLHQQQNAERLLAEFNQKAQTQFETAEELEGYFEQQQARLEDVEAELAEFVEVRSTQRQQREQLNQQYNQLAKTAPAWHTAQSALARLEEQCGEKFEASQSVMQFMQNMLTKEREATLARDELARREAALDAQITRLSQPDGSDDVRLNQLAERFGGVLLSELYDDVSIDDAPYFSALYGEARHAIVVRDLESVKAQLEKLDDCPTDLYLIEGDPSAFDDAVFTAEELAEGVVVKVSDRQWRYSKFPEVPLFGRAAREKHLETLKAERDEVSEQHAERAFDVQKCQRLHQHLSQFVGTHLSLAFQPNPEEQMQEIAAERTEIERELNQAAGNEQQLRSQLDSAKAKLQMLNKILPLVSLLEDETLADRAEECRAQLDEAEEDEQFVRQFGNYLTQLEPIAASLKSDPAKFEQLEQDYRQAKAEQKQVQQKVFALSDVIQRRVHFSYEEAIGSEGSALTEQLRTRLENAQREREQARDQLRQAQAQFTQYNQVLTGLRSSCDAKTQMLQELIREIDDLGVRGDIGAEERARSRRDELQQRLSQQRSRKGYLDKQLGTIEAEIDNLTRTLRKAERDYHTQRELVVQAKVSWCLVLKLSRNSDVEKRLNRRELAYQSAEELRSISDKALGALRTAVADNEYLRDSLRASEDSRKPENKVAFFIAVYQHLRERIRQDIIKTDDPIDAIEQMEIELSRLTNELTSREKKLAISAESVANILRKTIQREQNRILQLNQGLQNIAFGQVKGVRLVVNIRDTHAILLNALSNGREEHKDLFDSQKLSFSEALAMLYKRVNPHIEMGQRTPQTIGEELLDYRNYLDLEVETFRGADGWMRAESSALSTGEAIGTGMSILLMVVQSWEEESRRMRAKDILPSRLLFLDEAARLDATSINTLFELCERLDMQLLIAAPENISPERGTTYKLVRKITNNQEYVHVVGLKGFGQQ
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: FKGP_ARATH
Sequence: MSKQRKKADLATVLRKSWYHLRLSVRHPTRVPTWDAIVLTAASPEQAELYDWQLRRAKRMGRIASSTVTLAVPDPDGKRIGSGAATLNAIYALARHYEKLGFDLGPEMEVANGACKWVRFISAKHVLMLHAGGDSKRVPWANPMGKVFLPLPYLAADDPDGPVPLLFDHILAIASCARQAFQDQGGLFIMTGDVLPCFDAFKMTLPEDAASIVTVPITLDIASNHGVIVTSKSESLAESYTVSLVNDLLQKPTVEDLVKKDAILHDGRTLLDTGIISARGRAWSDLVALGCSCQPMILELIGSKKEMSLYEDLVAAWVPSRHDWLRTRPLGELLVNSLGRQKMYSYCTYDLQFLHFGTSSEVLDHLSGDASGIVGRRHLCSIPATTVSDIAASSVILSSEIAPGVSIGEDSLIYDSTVSGAVQIGSQSIVVGIHIPSEDLGTPESFRFMLPDRHCLWEVPLVGHKGRVIVYCGLHDNPKNSIHKDGTFCGKPLEKVLFDLGIEESDLWSSYVAQDRCLWNAKLFPILTYSEMLKLASWLMGLDDSRNKEKIKLWRSSQRVSLEELHGSINFPEMCNGSSNHQADLAGGIAKACMNYGMLGRNLSQLCHEILQKESLGLEICKNFLDQCPKFQEQNSKILPKSRAYQVEVDLLRACGDEAKAIELEHKVWGAVAEETASAVRYGFREHLLESSGKSHSENHISHPDRVFQPRRTKVELPVRVDFVGGWSDTPPWSLERAGYVLNMAITLEGSLPIGTIIETTNQMGISIQDDAGNELHIEDPISIKTPFEVNDPFRLVKSALLVTGIVQENFVDSTGLAIKTWANVPRGSGLGTSSILAAAVVKGLLQISNGDESNENIARLVLVLEQLMGTGGGWQDQIGGLYPGIKFTSSFPGIPMRLQVVPLLASPQLISELEQRLLVVFTGQVRLAHQVLHKVVTRYLQRDNLLISSIKRLTELAKSGREALMNCEVDEVGDIMSEAWRLHQELDPYCSNEFVDKLFEFSQPYSSGFKLVGAGGGGFSLILAKDAEKAKELRQRLEEHAEFDVKVYNWSICI
What is the function of this protein?
Bifunctional enzyme involved in the salvage pathway which converts free L-fucose to GDP-L-fucose.  The sugar-1-kinase activity has a strict substrate specificity for L-fucose and ATP.  The pyrophosphorylase activity has a strict substrate specificity for L-fucose 1-phosphate and GTP.
What are the official names of this protein?
Bifunctional fucokinase/fucose pyrophosphorylase, AtFKGP.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family.
Protein: EX7S_GLUDA
Sequence: MTEDLSQLSFEDALAQLEEIVRQLEGGQLRLQDAIASYERGAALRRYCDTKLNEADARVQAIIQRADGALETKSMD
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDM5B_CHICK
Sequence: MAEFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPPFACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKFWELQGCTLKIPHVERKILDLFQLNRLVAEEGGFDVVCKERKWTKIATRMGFAPGKAVGSHIRAHYERILYPYNLFQSGASLLCLQKPDLTSDTKDKEYKPHDIPQRQSVQPSESCPPARRAKRLRAEATNIKTESDSPEVRTHNLRRRMGCAPPKCENEKETYSAVKLAEKREHAGEQERDKAKARSKKPTSAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPQCLAQECNKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSGFPVRDGKFKVRPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGAPGYAAEQLEDVMKKLAPELFESQPDLLHQLVTIMNPNTLMAHGVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGRQCIEHYRLLSRYCVFSHDEMICKMASKADILDVVVASTVQKDMAIMIDDEKMLREKVQKLGVTDSERVAFELFPDDERQCYKCKTTCFMSAVYCPCKPGLLVCLYHVEDLCSCPTYQYKLGYRYTLEELYPMMNALKMRAESYNEWASNVNEALEAKISNKRSLISFKALIEESELKKFPDNDLLRHLRLVTQDADKCASVAQQLLNGKRQTRYRSGGGKCPNQLTVNELRLFVRQLYALPCVLSQTPLLKDLLDRVEAFQQQSQKLLSEEMPSAAELQELLDVSFDFDVDLPQLAELRVRLEQARWLEDVQMASAEQNSLTLDDMRRLIDSGVGLAPYPAVEKAMAKLQELLTVSEHWDDKARNLIKARPRQSLSSLVVAVKEIEEIPAYLPSGAALKDAVQKAQDWLQEVEALQVGGRVPVLDTLVELVTRGRSIPVHLDYLPRLESLVAEVQAWKECAANTFLCENSPYSLLEVLCPRCDIGTLGLKRKQKKLKEPMPSGKKRSTKLESLSDLERALSESKDTASAMATLGEARLKEMEALRSLRAANEGKVLCSEEDAELKVCVCQKEPAAPMIQCELCRGFFHTGCVSVPHALQGPRVWLCPQCRRSEKPPLEKILPLLASLQRIRVRLPEGDALRYMIERTVNWQHRAQQMLYSGNLKLLQDKVGSGLLYNRWQSTAGPLPETNKVSQTIGAMSFSMPHDWDNRTIYLHSPFSTGQQCIPLHVVSTELDELMMEAQLLQVSLPEIQELYQILFTKQSPSLQAEQKPSVGPSNEKSECCRGKKDGMSYMERKLKRRFERESFCDEKRARVRKMRTPKKKKLKLSHTKDVSSSSRMERERERLLEAQRSSESHLVPSDTSFSEQEDSEDEDAICPAVTCLQPEGEEVDWVQCDGSCNQWFHQVCVGISPEMAEKEDYICASCAGKGSPYRK
What is the function of this protein?
Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code.  Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'.  Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'.  Acts as a transcriptional corepressor.  May repress the CLOCK-BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2.
What are the official names of this protein?
Lysine-specific demethylase 5B, Histone demethylase JARID1B, Jumonji/ARID domain-containing protein 1B, [histone H3]-trimethyl-L-lysine(4) demethylase 5B.
What is the protein family that this protein belongs to?
Belongs to the JARID1 histone demethylase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ILVY_HAEIN
Sequence: MEFTDLQIFIHLSDTKNFTKTATQNHMSPSTLSRQIQRLEDELGKTLFIRDNRQVKLTEYGEKFLQFAKTEWQNWQQFKQQLKDESDELCGEIKLFCSVTASYSHLPHVLKEFRQRYPKVEIQLTTGDPALALELIQAQQVDLALAGKPNNLPSSVVFHKIDDISLSLIAPRVACLATQLLQEKPIDWQQMPFIFPVEGHARQRIEQWLREKQIKHPKIYATVAGHEGIVPMVGLGFGLAMLPDAVIDSSPMNNQISRLNLDKPIEPFELGICTQKRNLEQPLVRAFWAMLE
What is the function of this protein?
This protein activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate.  IlvY is also a negative regulator of its own expression (By similarity).
What are the official names of this protein?
HTH-type transcriptional activator IlvY.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y307_RHOPA
Sequence: MSMAGAERPVSSAAGLPVRWALAVVLGLLAIQATVLFAMGRVPICTCGTVKLWHGVVMSSENSQHLTDWYTFSHIIHGFLFYAGTWLLLRRWPWTARLIVAVLIEGAWELTENSSFIIERYRAGTISLDYYGDSIVNSVADTLAMISGFLLARWLPVTATVAIAVLFEVLVGLHIRDNLTLNVIMLIHPFDAIRQWQAGPPII
What are the official names of this protein?
UPF0314 protein RPA0307.
What is the protein family that this protein belongs to?
Belongs to the UPF0314 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROB_PSEPK
Sequence: MQTLKVDLGERSYPIYIGEGLLDQPELLAPHIAGRQVAIVSNETVAPLYLERLSKALGAYSVLPVVLPDGEAHKNWETLQLIFDGLLTARHDRRTTVVALGGGVIGDMAGFAAACYQRGVDFIQVPTTLLSQVDSSVGGKTGINHPLGKNMVGAFYQPKAVLIDTTSLKTLPARELSAGLAEVIKYGLICDKPFLAWLEDNMQALRALDSAALTEAIRRSCAAKAAVVGADERESGLRATLNLGHTFGHAIETHMGYGVWLHGEAVAAGTVMALEMSMRLGWIDQAERDRGIRLLQDAGLPVVPPQEMTPAHFMEHMAVDKKVLDGRLRLVLLRQMGEAVVTDDYSKEILQATLSADYRAIVAQL
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUON_HYDCU
Sequence: MNFVIPSFIPAIPEIVLLTLTSLLLIADTIWSKRSEFATYYATQLILLVVGYLVLTSFSTSQVLTFDGSFVRDAFGDILKLVIVVVSMGIFLFSKEYLLQNKFYRGEYFTLGLFGVLGMFVMVSAYNLITMYLGLEIMSLALYAMVAMRKDNQHALEAAMKYFVLGALATGMLLYGFSMIYGATGSIQFDEMAQIIASGNVDNVVLSFGVVFIVIGLAFKLGAVPFHMWVPDVYHGAPTAVTLYIGTAPKIAAFAMLYRILVEGLPGLVEDWQSLIVMISVLSLIVGAVITLVQENLKRLLAYSGIGHIGFILLGIIAANPDGYSAAMFYTIVYSITALAGFGMIVALARTNNEFDLVADFKGMNKRNPWLALMMLFIMFSMAGIPPFVGFYAKVVVIEEVVQAGFTWLAVLAVVMAVISAFYYLRVVKVMYFDEPEDNTKIEPVSSQLNWAVSFVSIALLLLGLMPSSLITLCYNSL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YYBM_BACSU
Sequence: MESHIYRIIKNKLTIIIFTIIILIPCVDISLLLMTNTEYHPAYAFFLSGTSVGHASQMILLWFLPLYFLLLCADDSIQDYKTGYHYILISKVGRKKYCLEKIFTSFIISFLTMFLSLILNFLLVQVFFFKGTFKNDLDQIKFPDNSLYTFSMAHPYIAIVLFSIICCIMSGFVGALGSSLSLLFRDKKYAYPASFFIWFVLILKNKSLMFLFQPFTEYGYNVLLPILCLSIFIFLIIISSIVLYEAKYNEN
What are the official names of this protein?
Uncharacterized protein YybM.
Protein: SPRTL_STRPN
Sequence: MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLDFNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLPNSNSKPIKLYRCQSCQQRYQRKRRIDTQRYRCGLCRGKLLLVNQPED
What are the official names of this protein?
Protein SprT-like.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_UREU1
Sequence: MKSLLGTKVGMTQVFTETGKAVAATVIYVEPNKVLAVKTNEKDGYNAIQIGYETVKEKALNKPLLGQFKKANSDPKRHIKEFRDVVAEVGAELTVSEFEPGQLVNAQAYTKGHGFTGSIKRHNFSMGPMGHGAGYPHRYVGSIAKGRGGSQAQRVFKGTKLPGHYGHELVTTKNLLVLDVKANENLILIKGAIPGPKGSIVLLKSAKKVGHIVSDPQVVNYLANKASSSEANK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: HIS2_BACAN
Sequence: MENTFKLLFETIEERKRNPLPESYTNYLFSKGEDKILKKIGEECTEVIIASKNNDKEELVKEMVDVLYHCFVLLAEKNIPLEDIMEEVTERNGKLSRVGDRREIDTL
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BPT_BORPD
Sequence: MSQLKELPFATLQFYSTAPYPCSYLPGQQARSQVAAPGHLINAGAYSQLVEQGFRRSGLFTYRPHCDNCRACVPVRVDTARFAPNRSQRRAWRGHQGLRAFVAELAWSPEHYDLYTRYQQGRHPGGGMDDDSRTQYAQFLLTSRVNTRLVEFRDAEGTLAMVSIIDVLDDGLSSVYTFYDPAARGSLGTYNVLWQIEQCRTLDLPWLYLGYWIRDSRKMAYKSGFKPLQLYLDGAWQAPPPGTL
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.