PharMolix/UniProtQA huggingface dataset:
Protein: PGMF_ASPTN
Sequence: MASTVPSTMKAWQFSSAYPTIEANLKLNNNAPLPDGAKNLGPDQVLVKVIAAGLNPVDFKFAEIPWLGRFIVGSPSTPGMDFAGRVVATGPNTKSVAVEDLKPGQLVFGRLDSPCKFGTLAEYTIAPRKGCVAIPPGARVIETACVASVGLTAYQSIVYRLKDHAGKRVFLNGGSGGCGTFGIQIAKQMGCHVTTSCSTPNVDLCRSLGADTVIDYKKTDVIAELKKMQPFDLVVDNVGVPTDLYWAAPSFTNPGAPYVQVGALAVTPGFILGNFFKARWPGWLGGGKRPWEFMHIESNVQDYEQLGRWMQEGKLRAVVDEVFGMQDDGAVKAYQKLRTGRAKGKIIVKIDETWED
What is the function of this protein?
FAD-linked oxidoreductase; part of the gene cluster that mediates the biosynthesis of pleosporalin A, ascomycone A, as well as a third cryptic naphthoquinone derived pigment, all responsible for the coloration of conidia (PubMed:28471414, PubMed:35351612).  The pathway begins with the biosynthesis of the cyclized heptaketide 3-acetonyl-1,6,8-trihydroxy-2-naphthaldehyde by the NR-PKS pgmA.  The C-6 hydroxyl group is further methylated by the O-methyltransferase pgmB to yield fusarubinaldehyde which is in turn oxidized by the cytochrome P450 monooxygenase pgmC at C-9.  The C-1 hydroxyl group is then methylated spontaneously.  Although pgmE, pgmD and pgmH are essential for the production of pleosporalin A, it is not the case for the 2 other final products and it remains difficult to assign a specific function to each enzyme.  PgmF and pgmG seem not to be involved in pigment biosynthesis although they were regulated by the cluster-specific transcription factor pgmR (PubMed:35351612) (Probable).
What are the official names of this protein?
Trans-enoyl reductase pgmF, Pigmented naphthoquinones biosynthesis cluster protein F.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: THAP7_MOUSE
Sequence: MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPTSEYIYFCSKHFEENCFELVGISGYHRLKEGAVPTIFESFSKLRRTAKTKGHGYPPGLPDVSRLRRCRKRCSERQGPTTPFSPPPRADIICFPVEEASAPATLPASPAVRLDPGLNSPFSDLLGPLGAQADEAGCSTQPSPEQHPSPLEPQPASPSAYMLRLPPPAGAYIQNEHSYQVGSALLWKRRAEAALDALDKTQRQLQACKRREQRLRLRLTKLQQERAREKRAQADARQTLKDHVQDFAMQLSSSMA
What is the function of this protein?
Chromatin-associated, histone tail-binding protein that represses transcription via recruitment of HDAC3 and nuclear hormone receptor corepressors.
What are the official names of this protein?
THAP domain-containing protein 7.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RBSA2_RHIME
Sequence: MTSETVLEIRNVSKHFGAVKALTAVDFRLARGEVHALCGENGAGKSTLMNVIAGVLQPSEGEVLIEGAPVKIASPAVAQSLGIALVHQEIALCPDATIAENMFMAATNRRRSALMNYAQLERDAQAVMNRLAPIDVSQKVGDLPISSQQLVEIAKALTLDCRVLIFDEPTAALTETEAQVLFGIIRDLKARGISIIYISHRMAEVFSLCDRVTVFRDGRYVATEMVSDVTPDDVVRLMVGREISQLYPDKQPSSERLGEPILSVRDLGGERFRDVSFELRYGEILGVGGLIGSGRTEIAEGICALRPVTQGEIRLHDKVLRLRRYSDAAKAGVVYLSEDRKGSGVFLDLSIAQNIAALDLKALTSLGLLNSREERALAEDLTRRLGVRMGGVDMPVSSLSGGNQQKVAIAKQLAVDPKVILMDEPTRGIDVGAKSEIHRLLRELARAGIGILVISSELPELIGLCDRVLVVREGRIAGEVSGNEMTEEVIMRLASGIGPATETNLKASGHAA
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TRPD_BUCAI
Sequence: MRNILLKIYDSKFLNQEESYQLFTLISSGKITDIKLASILTAMKIRGESIEEITGAIKAFLDKMKYFPKPDYIFSDIVGTGGDAKNTINISTMSAFVAATCGLKIIKHCNQRISSKSGSSDILEKFNINLNASPEKSRKTLDQLNICFLFAPKYHDGFKYSNNVRTDLKTKTIFNFLGPFLNPATPPLSVIGVYNKNLINIAVNILKNLQYKRAIVLHSDNTDEVTLYGTTYVSELLNKKIISYQLQPESFGLKMHPKKILKINSLEENYHIIKEIMKGKGSKLYEELIAVNVAMLLKVFGYENLKENTKLALNKIRSGDVYKHIRNVANMLKEDNHARHNT
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: APD22_APIME
Sequence: MKNFALAILVVTFVVAVFGNTNLDPPTRPTRLRREAEPEAEPGNNRPVYIPQPRPPHPRLRREAEPEAEPGNNRPVYIPQPRPPHPRLRREAEPEAEPGNNRPVYIPQPRPPHPRLRREAEPEAEPGNNRPVYIPQPRPPHPRI
What is the function of this protein?
Apidaecins have bactericidal activity; predominantly against Gram-negative bacteria (PubMed:2676519, PubMed:7929322).  They seem to interfere with cell propagation (PubMed:2676519).
What are the official names of this protein?
Apidaecins type 22.
What is the protein family that this protein belongs to?
Belongs to the apidaecin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS13_PROM0
Sequence: MARIAGIDIPREKRVEIALTYVYGIGLTRSKLILANTGVNPDTRVKDLSDSDVQKLRGATEEFTLEGDLRRKEGMALKRLQDIGCVRGRRHRMSLPVRGQRTRTNARTRRGSRKTVAGRKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: UVRC_FRAT1
Sequence: MIVDNSKDFDLKSFLANLTTHSGVYRMLDKHGEIIYVGKAKNLKNRVNSYFSKGAKDSKTLMMVEQIARIEITITPSDYEAYLLENNLIKQHRPKYNILFKDDKSYPYLVISRDKFPRVSFYRSKSAYKKGQCFGPYVSISSVKNTLNTIQKIFPIRQCENSYYKSRVRPCLQYQIKCCLAPCVGLVSQQQYDEQLAILKKFLAGKFSSVLEEISAKMYQASEDMEYEKAQVYRDQLVVLRKLQQQQIVDIQEDKTFDVIGIYMQDSYASIALLQIQNGDVVADRHWSIDAKGQDKTSIMHAFLSHFYLGDEIRNIWPKNIILSKVEFADITDLMNSISQKIGQAINWIIAPAADNLKWLKLAEVNARQKLNIYTSSKSQYQKRLESLKEFLELEKDIKRIECFDISHFQGEATIASCVVYTDDGEDRKSHRRYNIKDIKSGDDYAAIHQAVSRRVSSGLEADNLPDVMIIDGGKGQIHQAEAVFREYGIQDKVQLVSLGKGIERISGKEKIYKGFDDTEYTLDEHNPGFLLLRQVRDSAHDHAIKGQRKKVSANRQSSIIEEIEGVGPKRRKALMMYFGGWQELSRASVDEIAKVKGISKKLAQEIWECFH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_OSTLU
Sequence: MGFLFTSESVNEGHPDKLADQISDGILDACLAQDPDSKVACETATKTNMVMVFGEITTKAKVDYEAVVRQVCRDVGFISDETGLDGNKCRVLVELHDQSPDIGQGVHGMGTKSDEDIGAGDQGHMFGYATDETPELMPLTHVLATKLGHRLTVVRKDGTCPWVLPDGKTQVTIEYENEGGAMVPKRVHTILISTQHIEGVTNEKIAEDLMNEVIKKVVPEKYLDADTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYISRQAAKSVVAAGLARRCLFQISYAIGVAEPLSVHVDTYGTGKIPDSEILAKVKAAFDFRPGMMGKALDLKRGGNKRYQTTAAYGHFGRDEDLDIFTWEKVVPL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, Methionine adenosyltransferase, MAT.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISU3_ARATH
Sequence: MLRQTTKRAFLGLASQNPTPFPVVSRLYHPNVIDHYDNPRNVGSFDKNDPNVGTGLVGAPQCGDVMKLQVKFDGSGQIIDAKFKTFGCGSAIAASSVATEWVKGKSVEEVLTIKNSQIAKHLSLPPVKLHCSMLAEDAIKAAIKNYKEKQDKANGETVETIDSTYLHGIGS
What is the function of this protein?
Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins (PubMed:17417719).  First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISCU (ISU1, ISU2 or ISU3).  In a second step, the cluster is released from ISCU, transferred to a glutaredoxin, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins.  Cluster assembly on ISCU depends on the function of the cysteine desulfurase complex NFS1-ISD11, which serves as the sulfur donor for cluster synthesis, the iron-binding protein frataxin as the putative iron donor, and the electron transfer chain comprised of ferredoxin reductase and ferredoxin, which receive their electrons from NADH (By similarity).
What are the official names of this protein?
Iron-sulfur cluster assembly protein 3, AtISU3, Protein ISCU-LIKE 3, NifU-like N-terminal domain-containing protein ISU3, NifU-like protein ISU3.
What is the protein family that this protein belongs to?
Belongs to the NifU family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CYB_NOTCC
Sequence: MTNLRKTHPLMKIINNSFIDLPTPSNISSWWNFGSLLGICLIIQILTGLFLAMHYTSDTLTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYLFMETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGSDLVQWIWGGFSVDKATLTRFFAFHFILPFIIAALAGVHLLFLHETGSNNPSGISSDADKIPFHPYYTIKDILGILLLILTLASLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILILSPLLHTAKQRSMMFRPFSQCLFWILVADLLTLTWIGGQPVEHPFIIIGQVASILYFSLILIIMPITSLLENKMLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GSH1_SALG2
Sequence: MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTDFAEALLEFITPVDGDIQHMLTFMRDLHRYTARKLGDERMWPLSMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGVTEGEAAKEKISAGYFRLIRNYYRFGWVIPYLFGASPAICSSFLQGKPTTLPFEKTDCGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLHEYVAGLKRAIKTPSEEYARIGVEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCVLADAPEMSSDELLCTRTNWSRVILEGRKPGLTLGIGCETAQFPLPKVGKDLFRDLKRVAQTLDSIHGGEEYQKVCDELVACFDNPELTFSARILRSMIDEGIGGTGKAFGEAYRNLLREEPLEILQEEEFIAERDASVRRQQEIEAADTEPFAAWLAKHA
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: LSS_HUMAN
Sequence: MTEGTCLRRRGGPYKTEPATDLGRWRLNCERGRQTWTYLQDERAGREQTGLEAYALGLDTKNYFKDLPKAHTAFEGALNGMTFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARIPLPAGYREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNILHKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPMSYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALLNLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQEHVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRLSQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEKCPHVTEHIPRERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQALKYFHKRFPEHRAAEIRETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTWFGLEAFACMGQTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYLQSAQSQIHNTCWAMMGLMAVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRFSQLYPERALAGHP
What is the function of this protein?
Key enzyme in the cholesterol biosynthesis pathway.  Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus (PubMed:14766201, PubMed:7639730, PubMed:26200341).  Through the production of lanosterol may regulate lens protein aggregation and increase transparency (PubMed:26200341).
What are the official names of this protein?
Lanosterol synthase, 2,3-epoxysqualene--lanosterol cyclase, Oxidosqualene--lanosterol cyclase, OSC, hOSC.
What is the protein family that this protein belongs to?
Belongs to the terpene cyclase/mutase family.
Protein: HCAF_SHIBS
Sequence: MSAQVSLELHLRISQFLFHEASLLDDWKFRDWLAQLDEEIRYTMRTTVNAQTRDRRKGVQPPTTWIFNDTKDQLERRIARLETGMAWAEEPPSRTRHLISNCQISETDIPNVFAVRVNYLLYQAQKERDETFYVGTRFDKVRRLEDDNWRLLERDIVLDQAVITSHNLSVLF
What is the function of this protein?
Part of the multicomponent 3-phenylpropionate dioxygenase.  Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively.
What are the official names of this protein?
3-phenylpropionate/cinnamic acid dioxygenase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.
Protein: MURC_PARP8
Sequence: MKHIVKHIHFVGIGGAGMSGIAEVLVNLGYQVSGSDLSRNAVTERLAALGARIAIGHDAANIEGANAVVVSTAVRSDNPEVLAARHRRIPIVPRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAEADESDASFLNLFPVIEVITNIDADHMDTYGHDFARLKQAFIEFTHRLPFYGIAVLCVDDPNVKEILPFVSKPIIRYGFAPDAQVRAVNVEAREGKMHFTAMREDAPPIDIVLNLPGLHNVQNALAAIAIATELEVKDADIQRALADFNGVGRRFQRYGEVTVTSGGAYTLVDDYGHHPVEMAATIAAARGAFPDKRLVLAFQPHRFTRTRDCFEDFVKVLSTVDALVLTEVYSAGEAPIVAADGRSLTRAIRVAGKVEPVFVDTVDEVPDALGAIVRDGDVVITMGAGSIGSVPGRLAGNEGVK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_SHEB5
Sequence: MNVVQGNIEAKNAKVAIVISRFNSFLVESLLEGALDTLKRFGQVSDDNITVVRVPGAVELPLAARRVAASGKFDGIIALGAVIRGGTPHFDFVAGECNKGLAQVALEFDLPVAFGVLTTDTIEQAIERSGTKAGNKGGEAALSLLEMVNVLQELEQQLL
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: NHAA_BARBK
Sequence: MLDLSSNRLPNRASLITNRAFSAIERFLHIEAMSGVVLLLAAATALILANSQYTSLYEAFWHTPLGFNFGHFNLSWDLHFWVNDVLMTIFFLVAGMEIRREIHEGALASVKQAILPIVAAIGGVCIPAIIYLSFNFNGGHIYGWAVPTATDIAFALGILALLGKAIPSNLHIILLSLAIIDDIMAVLIIAFFYSTNLDPSGLAIAAAGIALVFFFQWISFASAWLYVLPGAIIWWGLMVTGIHPSLAGVILGMMTPVFPTRNLVSPLTTLSNAIQTLQEKNTNTDLHHISTTLKKMRKGQRDIVAPVIRIQKELHPWVAYGVMPIFAFANAGVSFANFDLASQKSFLIVLGIIIGLCIGKPLGILAASYLAVKSGLCRLPPHVTWTGILLIGFLAGIGFTMSIFVSMLAFQDIAQLNSAKIGVLCGSGLSALAGLGYGLIYIKNNKKTHNKP
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEPA_STRS7
Sequence: MNSQELKKRQENIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYKAKNGQTYIFHLIDTPGHVDFTYEVSRSLAACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVIGLDASEAVLASAKSGIGIEDILEQIVEKVPAPSGDVDQPLQALIFDSVYDAYRGVILQVRVVNGMVKPGDTIQMMSNGKTFDVTEVGIFTPKAIGRNFLATGDVGYIAASIKTVADTRVGDTVTLATNPAAEPLHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGDMLEVSNPSEFPDPTKVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYHIPLAEIVFDFFDKLKSSTRGYASFDYEIAEYRRSQLVKMDILLNGDKVDALSFIVHRAFAYERGKLIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDESKK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CBID_CLOBB
Sequence: MFEMYIESGMNKLRCGYTTGSCATGAAKAATMLLFDLINSEEELNEIEIDTPKGIKVEMPIDHVVVGKNFVQCTILKFSGDDKDITMGLEIQATVEKISKEEAEELSKKLISNESKIIVLDGGIGVGRVTKDGLFVAKGEPAINPVPRQMIIKEIESILPKDKYVKVIISVPQGTEIGKKTFNPRLGIEGGISILGTSGIVYPMSEDALKASIKLEIKQKSLKNKNLILTFGNLGENYCKSLGYIEEEIIICSNFIGFALECCVSCKVKSILIVGHIGKMSKIAYGCFNTHSRVCGVRLEVLALELTLLGYDVSLVNKVLNEKTCEGAVKLLGSGYENLYKNIGKKILNSMKTYVYDELKIDAVMYYGASNPILLWSSCLE
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: DBP5_YEAST
Sequence: MSDTKRDPADLLASLKIDNEKEDTSEVSTKETVKSQPEKTADSIKPAEKLVPKVEEKKTKQEDSNLISSEYEVKVKLADIQADPNSPLYSAKSFDELGLAPELLKGIYAMKFQKPSKIQERALPLLLHNPPRNMIAQSQSGTGKTAAFSLTMLTRVNPEDASPQAICLAPSRELARQTLEVVQEMGKFTKITSQLIVPDSFEKNKQINAQVIVGTPGTVLDLMRRKLMQLQKIKIFVLDEADNMLDQQGLGDQCIRVKRFLPKDTQLVLFSATFADAVRQYAKKIVPNANTLELQTNEVNVDAIKQLYMDCKNEADKFDVLTELYGLMTIGSSIIFVATKKTANVLYGKLKSEGHEVSILHGDLQTQERDRLIDDFREGRSKVLITTNVLARGIDIPTVSMVVNYDLPTLANGQADPATYIHRIGRTGRFGRKGVAISFVHDKNSFNILSAIQKYFGDIEMTRVPTDDWDEVEKIVKKVLKD
What is the function of this protein?
ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus.  May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex.  Contributes to the blocking of bulk poly(A)+ mRNA export in ethanol-stressed cells.  May also be involved in early transcription.
What are the official names of this protein?
ATP-dependent RNA helicase DBP5, DEAD box protein 5, Helicase CA5/6, Ribonucleic acid-trafficking protein 8.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Nuclear pore complex cytoplasmic fibrils. Accumulates in the nucleus rapidly and reversibly in response to ethanol stress.
Protein: PROB_LIGS1
Sequence: MENRNLQDAKRIVVKVGTSSLIRANGKINLQAIDELCYTLSGLVNEDKEVVLVSSGAVGVGLANMGLVQRPKQIPEQQALAAIGQSQLMTIYQQRFAMYSQKTSQILLTHDVLTYPESRENVLNTFNELLKWKVIPVVNENDTVAVDEMDHQTSFGDNDWLSAVVASGIDADLLIVLSDIDGLFNKNPKKYADANLISEVTEINEKITGAAGGTGSRFGTGGMATKIKAMDRMINEGRKAVLANGKRPSIIFEILNGKQIGTLFHKK
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_MYCA9
Sequence: MTDPLSRAGLVIVDKPAGMTSHDVVSRCRRIFSTRKVGHAGTLDPMATGVLVIGIERATKIMGLLTLTTKSYAATIRFGQSTSTDDAEGEVLQTISASHLTEVDIEAAVAGLRGDIAQVPSSVSAIKVDGQRAYKLAREGQSVELAARPVRISRFDVLAVRGSGEDLIDVDVEIDCSSGTYIRALARDAGAALGVGGHLTALRRTRVGDFGLDRARTLEELADGATLTLDLDSACRQGFPRRDLDAAEVDAVRNGRPLAPAGIEGTYAAVDADDRVIALLADKGSRTTSVVVLRPANL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: SYP_PSYCK
Sequence: MKASQFLFATLKETPSDADIASSQLMVRAGLIRKIASGLYIWLPMGLRVLQKVERIVREEMQNIGAQEVLMPMTQPAELWQLTGRFNDYGPELLRFKDRHDRDFVLGPTHEEVITNLAQGELRSYKQLPITFFQIQNKFRDEIRPRFGVMRAREFTMKDAYSFHVDQASLAKTYDEMYDAYTRIFTRLGLDFRAVQADTGSIGGFASHEFHVLADSGEDDIAFSDSSEYAANVELAESVSMAERQPATMARENIDTVNMPTCEAVAEHLNVPLATTVKTLIVQGHTPEGEPQLIAVVLRGDHTLNTIKAEKIEEANVPLMMATEEELKAAGLHKGYIGVELNMPVFVDRAAAALSDFVSGANEINKHTTGMNWERDAHITRIVDIRNVHEGDPSPDGKGTLQIKRGIEVGHIFQLGDKYSQAMNCTVSGEDGKPVTLMMGCYGIGVSRIIAAAIEQNNDENGIMWPSTPDISDSLAPFEVAIVPMKSKEDTVMETATALYEELKALGINVLLDDRNERPGVKFADLELIGIPHRIVVSDRNLAEDKYEYVNRRDSEKQLLSRDEVIAKVSGK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3SOF7_NAJAT
Sequence: MKTLLLTLVVVTIVCLDLGYTLKCHNTQLPFIYNTCPEGKNLCFKATLKFPLKFPVKRGCAATCPRSSSLVKVVCCKTDKCN
What are the official names of this protein?
Cytotoxin 7, Cardiotoxin-7, CTX7, Ctx-7, Cardiotoxin-like basic protein 2, CLBP2.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Orphan group XV sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GGACT_BOVIN
Sequence: MPGPECKWSTTETGAPCGTDDSSGRLAPVFVYGTLKTGQPNHRVLLDGAHGRAAFRGRAHTLEPYPLVIAGEHNIPRLLNLPGRGHRVFGEVYEVDERMLRFLDEFESCPDMYQRTRLHVALEGVRGPLECFVYTTATYPPEWVHLPYLDDYDSQGKHGLRYNPRENR
What is the function of this protein?
Contributes to degradation of proteins cross-linked by transglutaminases by degrading the cross-link between a lysine and a glutamic acid residue.  Catalyzes the formation of 5-oxo-L-proline from L-gamma-glutamyl-L-epsilon-lysine.  Inactive with L-gamma-glutamyl-alpha-amino acid substrates such as L-gamma-glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine.
What are the official names of this protein?
Gamma-glutamylaminecyclotransferase, GGACT, AIG2-like domain-containing protein 1, Gamma-glutamylamine cyclotransferase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamylcyclotransferase family.