PharMolix/UniProtQA huggingface dataset:
Protein: NRDR_HELMI
Sequence: MRCCYCGHGESKVLETRSAEEGRVIRRRRECMECNRRFTTLERIEETPLIVRKKGGSLEAFDRNKLLSGLLKACEKRPIPLDRLEELVTTVERDLRSQYDREVPSREIGEMLMARLRNIDEVAYVRFASVYRQFTDVGRFLEELEGLLKRKT
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: AUXI1_ARATH
Sequence: MDDFTGLLARDFGLKPQGKSAPMASQSNSSAADFNTFASSYSFATAAGKKSDSLPVFDDPGRDGDDLLFKDVFSGPPPPKYGSSSGDSRSPSAPAFDYDAMFKEPKSKSASSMPVYDKPVYDDEDVFESIPELKIPSTSSQSARFENVFSSISSSPTKHRKQNSSPFDDLMGNNLGKKGADSDREEKGSSIFDDLIPGFGRTSSPPSKRTTSETTNQSEKAPYRTAETSSNVEEDPFVVLEESESTPREPSRTDPLDDIGKFNSRKTDHSSVHGGVFVDIDPLDNLGKPGPDMNSKGKSHLRPPGNISGSQSPPVESPGSYHSKKVSFEDFLEPHNMSTPPPTNSNGSFESSDDVWLTVSEIPLFTQPTSAPPPTRPPPPRPTRPIKKKVNEPSIPTSAYHSHVPSSGRASVNSPTASQMDELDDFSIGRNQTAANGYPDPSSGEDSDVFSTAAASAAAMKDAMDKAEAKFRHAKERREKENLKASRSREGDHTENYDSRERELREKQVRLDRERAEREAEMEKAQEREKEEREREQKRIERERERLVARQAVERATREARERAATEAHAKVQRAAVGKATDARERAERAAVQRAHAEARERAAAGARDKAAKAAAEAREKAEKAAAEAKERANAEAREKETRVRAERAAVERAAAEARGRAAAQAKAKQQQENTNDLDSFFSSISRPNSAPRQRTNPLDPFQDSWNKGGSFESSRESLRVPPGQPENLRKTSSVTNIVDDLSSIFGASASQSGGFQDVDGETEERRRARLERHQRTQERAAKALAEKNERDLQVQREQVEKDRIGVTLDVEIKRWGAGKEGNLRALLSTLQYVLWPECGWQPVSLTDLITAASVKKVYRKATLCIHPDKVQQKGANLQQKYIAEKVFDMLKEAWNKFNSEELF
What is the function of this protein?
Promotes uncoating of clathrin-coated vesicles.  May interact directly with clathrin.
What are the official names of this protein?
Auxilin-related protein 1, Auxilin-like protein 1.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network. Endoplasmic reticulum. Cytoplasmic vesicle.
Protein: S29A4_DANRE
Sequence: MGSKGAERRKQATPGQTPEGNVVMSFSFESYQLEEEDCQGKDISDKGVLALSEPAFEEAVPDDRYHGIYFAMLLAGVGFLLPYNSFITDVDYLHHKFEGTSIVFDMGLTYILVALVAVILNNVLVEMLSLHTRITVGYLFALGPLLFVTIFDVWLERFTIKQAYVINLMSMGTVAFGCTVQQSSFYGYMGMLPKRYTQGVMTGESTAGVIISLSRIFTKLLIKDERKNTIIFFVISICMVLVCFILHLLVRRTRFVQYYTSLARRGLSHAKDHSQHASQYQVHHDVITEEGNGAVGCSPAGDGCADFAGGNTYVRFDVPKPKMKRSWPGVKDMILHRYVVARVIWTYMLSIAVTYFITLCLFPGLESEIKNATLGEWLPILIMAIFNISDFVGKILAAVPYEWNGTRLLFFSCVRVVFIPLFIMCVYPAQMPMFSHPAWPCIFSLFMGITNGYFGSVPMIHAAGKVAPEQRELAGNIMTVSYMSGLMLGSVVAYAAYSFTASGSSFHSQTGYNFTQGY
What is the function of this protein?
Functions as a polyspecific organic cation transporter, efficiently transporting many organic cations such as monoamine neurotransmitters 1-methyl-4-phenylpyridinium and biogenic amines including serotonin, dopamine, norepinephrine and epinephrine.  May play a role in regulating central nervous system homeostasis of monoamine neurotransmitters.  May be involved in luminal transport of organic cations in the kidney and seems to use luminal proton gradient to drive organic cation reabsorption.  Does not seem to transport nucleoside and nucleoside analogs such as uridine, cytidine, thymidine, adenosine, inosine, guanosine, and azidothymidine (By similarity).
What are the official names of this protein?
Equilibrative nucleoside transporter 4, Solute carrier family 29 member 4.
What is the protein family that this protein belongs to?
Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TPO4_YEAST
Sequence: MPSSLTKTESNSDPRTNIQQVPKALDKNVTNSGNLDSTSSSTGSITEDEKRSEPNADSNNMTGGEPIDPRDLDWDGPDDPDNPHNWSSLKKWYTTMTSAFLCLVVTMGSSLYVSSVPELVERYHVSQTLALAGLTFYLLGLSTVIGAPLSEVFGRKPVYLFSLPVSMLFTMGVGLSNGHMRIILPLRFLSGVFASPALSVGSGTILDIFDVDQVSVAMTYFVLSPFLGPVLSPIMAGFATEAKGWRWSEWIQLIAGGLILPFIALMPETHKGIILRKRAKKRNIALKKFSREAQKEFLKTTVTITILRPLKMLVVEPIVFVFSVYVAFIFAILFGFFEAYAVIYRGVYHMSMGISGLPFIGIGVGLWIGAFFYLYIDRKYLFPKPPAGTQPLTEKERTSKRTTPYRGARDAETGELLPVVPEKFLIACKFGSVALPIGLFWQAWTARSDVHWMAPVAAGVPFGFGLILIFFSVLMYFSTCYPPLTVASCLAANNLLRYVMSSVFPLFTIQMYTKMKIKWASTLFALVCVVMIPIPWVFEKWGSKLRHKSQFGYAAMEKEAETEGGIDDVNAVDGELNLTRMTTLRTMETDPSTREKPGERLSLRRTHTQPVPASFDREDGQHAQNRNEPISNSLYSAIKDNEDGYSYTEMATDASARMV
What is the function of this protein?
Cell membrane polyamine/proton antiporter, involved in the detoxification of excess polyamines in the cytoplasm.  Recognizes spermidine, spermine and the antimalarial drug quinidine, but not quinine, chloroquine and mefloquine.
What are the official names of this protein?
Polyamine transporter 4.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. Polyamines/proton antiporter (TC 2.A.1.2.16) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YR854_MIMIV
Sequence: MKEAVKTVKPKVPAKKRIVTGSKTKKKVFVKKKPPAKKPPDKKPLKKTTKKTVKKVINRPKSIHIPNKDLKIFKWIPTPKKEFTEIETNSWYEHRKFENPNKSPIQTYNKIVPVVPPESIKQQNLANKRKKTNRPIVFISSEKIRIYPTKEQQKILQTWFRLFACMYNSSIDYINSKKVVLESGRINVAATRKVCNKISVRKALKTIRDNLIKSTNPSIMTHIMDEAIGLACSNYKTCLTNYIEGQIKKFDIKPWSISKRRKIIVIEPGYFKGNSFCPTVFPKMKSSKPLIMIDKTVTLQYDSDTRKYILFVPRVTPKYSVNKEKNSCGIDPGLRDFLTVYSENETQSICPIEIVVNTTKNEYKKIDKINEIIKTKPNLNSKRKKKLNRGLRKYHRRVTNKMKDMHYKVSHELVNTFDKICIGKLNVKSILSKANTVLKSALKRKLATLSFYRFTQRLTHMGYKYGTEVVNVNEYLTTKTCSNCGKIKDLGASKIYECESCGMYADRDENAAKNILKVGLKPWYKQK
What are the official names of this protein?
TnpB-like protein R854.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transposase 35 family.
Protein: MATK_TOBAC
Sequence: MEEIQRYLQPDRSQQHNFLYPLIFQEYIYALAHDHGLNRNRSILLENPGYNNKLSFLIVKRLITRMYQQNHFLISTNDSNKNSFLGCNKSLYSQMISEGFAFIVEIPFSLRLISSLSSFEGKKIFKSYNLRSIHSTFPFLEDNFSHLNYVLDILIPYPVHLEILVQTLRYWVKDASSLHLLRFFLHEFWNLNSLITSKKPGYSFSKKNQRFFFFLYNSYVYECESTFVFLRNQSSHLRSTSFGALLERIYFYGKIERLVEVFAKDFQVTLWLFKDPFMHYVRYQGKSILASKGTFLLMNKWKFYLVNFWQCHCSLCFHTGRIHINQLSNHSRDFMGYLSSVRLNPSMVRSQMLENSFLINNAIKKFDTLVPIIPLIGSLAKANFCTVLGHPISKPVWSDLSDSDIIDRFGRICRNLFHYYSGSSKKKTLYRIKYILRLSCARTLARKHKSTVRTFLKRSGSELLEEFLTSEEQVLSLTFPRASSSLWGVYRSRIWYLDIFCINDLANYQ
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CK5P1_DROME
Sequence: MKISYRAFVRQVRHASTTASKGATTSVTSSAAGQLKSEPAARATFLERIQRGPGFQDFFAVKPASRLKTDEEEHVDTSVPYLNSIDFNGNGRKVHFEVYGCQMNTNDTEVVFSILKENGYLRCQEPEEADVIMLVTCAVRDGAEQRIRNRLKHLRAMKNKRSTRRHPLQLTLLGCMAERLKEKLLEQEQCVDVIAGPDSYKDLPRLLAISRHYGNSAINVLLSLDETYADVMPVRLNSESPTAFVSIMRGCDNMCTYCIVPFTRGRERSRPLASIVAEVKALAEQGVKEVTLLGQNVNSYRDRTAQEEQDSLKATPVPGFSTVYKPKTGGTPFAALLRSVAQAVPDMRIRFTSPHPKDFSDEVLEVIRDHPNVCKQLHLPAQSGNTQVLERMRRGYSREAYLELVQHIRQFLPNVGLSSDFICGFCGETEEEFQDTVSLIQQVQYNVAYLFAYSMREKTTAHRRYKDDVPINVKNERLQRMVQVFREGATQLHRKMEGQEQLILIEGKSKRSDAHWFGRNDANIKVIVPSIYVPISGDSTARKSFGVGDFLAVRIEESNSQVLKGTPLELSNITDFHSRQLIQ
What is the function of this protein?
Potential regulator of CDK5 activity.
What are the official names of this protein?
CDK5RAP1-like protein.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
Protein: ACDH5_RHOOB
Sequence: MTKALAAIVGSGNIGTDLMYKLLRSEIIEPRWMIGVDPESEGLKRAADRGVIASAEGVDWLLARDERPDIVFEATSAYVHRANAPRYRELGIQAVDLTPAALGPAVVPAVNMGEHRTAPNVNLITCGGQATIPMVHAVSRITDVAYAEIVASVASPSAGPGTRANIDEFTITTSRGIETIGGAKKGKAIIILNPAEPPMFMKDTVFCSIPADADRDAITASIHDVAASVQAYVPGYRLRAEPQFDDPTPISRGLARVGIFLEVEGAGDFLPPYSGNLDIMTAAATKVGESFATQILGASV
What are the official names of this protein?
Acetaldehyde dehydrogenase 5, Acetaldehyde dehydrogenase [acetylating] 5.
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: RS8_GLAP5
Sequence: MSMQDPIADMLTRIRNGQAANKVAISMPSSKLKVAIASVLAEEGYVESFKVVEGSKPELEITLKYFQNKPVVESIQRVSRPGLRIYKRKDELPKVMGGLGIAVVSTSKGVMTDRAARQASLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: VPR_HV1MA
Sequence: MEQAPADQGPQREPHNEWTLELLEELKQEAVRHFPRIWLHSLGQHIYETYGDTWEGVEAIIRSLQQLLFIHFRIGCQHSRIGITRQRRARNGSSRS
What is the function of this protein?
During virus entry, plays a role in the transport of the viral pre-integration (PIC) complex to the host nucleus.  This function is crucial for viral infection of non-dividing macrophages.  May act directly at the nuclear pore complex, by binding nucleoporins phenylalanine-glycine (FG)-repeat regions.
What are the official names of this protein?
Protein Vpr, R ORF protein, Viral protein R.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPR protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host extracellular space. Note=Incorporation into virion is dependent on p6 GAG sequences. Lacks a canonical nuclear localization signal, thus import into nucleus may function independently of the human importin pathway. Detected in high quantity in the serum and cerebrospinal fluid of AIDS patient.
Protein: PDXT_METS3
Sequence: MITIGILNLQGAVSEHYDITKKAIENMGIEAEAISVRYADEVANCDGVIISGGESTVIGKIIKERGIDKVIKDNRIPVFGTCAGMVLLGKKTDFDQPLLGIMDISVKRNAFGRQVDSFESPISILGEDYLGVFIRAPSLDDYDKTKEDIKVLSKLDDEIIAIQQGHNIAIAFHPELTDDTRIHEYFIEEVLNCVE
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: RNB_ENT38
Sequence: MLQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSYFIPPPQMKKVMHGDRVTAVIHTQKDRETAEPEELIEPFLTRFVGKVHKKDDRLSIVPDHPLLKDAIPCRADRNCEHDFKEGDWAVAQMRRHPLKGDRGFYADLTHFITYSDDHFVPWWVTLARHNLEKEAPNGVATEMLDEGLERRDLTALNFVTIDSASTQDMDDALYVEEGADGKLHLTVAIADPTAWIAEGSKLDDSAKVRAFTNYLPGFNIPMLPRELSDDLCSLRPNQIRPVLACRMTIAADGTIEDDIEFFAATIESKAKLAYDDVSNWLEGAGNWKPESEAIAQQITLLQRVCLSRGEWRKTHALVFKDRPDYRFVLGEKGEVLDIVAEPRRIANRIVEESMIAANICAARVLRDKLGFGIYNVHTGFDPANTEALAALLKTHDVHVDPQEVLTLEGFCKLRRELDAQPSGFLDSRIRRFQSYAEISTEPGPHFGLGLEAYATWTSPIRKYGDMVNHRLLKAIVKGETIARPQDEATVQMAERRRLNRMAERDVGDWLYARFLSDKAGTDTRFAAEIIDISRGGMRVRLVENGAVAFIPAPFLHAVRDELVCSQENGSVQIKGETVYKVTDVIDVNIAEVRMETRSIIARPVV
What is the function of this protein?
Involved in mRNA degradation.  Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
What are the official names of this protein?
Exoribonuclease 2, Exoribonuclease II, RNase II, Ribonuclease II.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_BEUC1
Sequence: MSVSIKPLEDRIVVKTLEAEQTTASGLVIPDTAKEKPQEGEVLAIGPGRVDDNGNRVPVDVAVGDVVIYSKYGGTEVKYAGQEYLILSARDVLAVVQK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS27A_PICTO
Sequence: MEKRELYELKDNKIVRKRRFCPRCGPGVFLAEHEDRFSCGRCGYTEFKRKN
What are the official names of this protein?
30S ribosomal protein S27ae.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS31 family.
Protein: DS13B_HUMAN
Sequence: MDSLQKQDLRRPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRETGRF
What is the function of this protein?
Dual specificity phosphatase that dephosphorylates MAPK8/JNK and MAPK14/p38, but not MAPK1/ERK2, in vitro (PubMed:21360282).  Exhibits intrinsic phosphatase activity towards both phospho-seryl/threonyl and -tyrosyl residues, with similar specific activities in vitro (PubMed:10585869).
What are the official names of this protein?
Dual specificity protein phosphatase 13 isoform B, DUSP13B, Dual specificity phosphatase SKRP4, Testis- and skeletal-muscle-specific DSP.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Protein: AGDC_ASPOR
Sequence: MLGSLLLLAPLAGAAVIGSRADTQQCPGYKASNVQENDRSLTADLTLAGKPCNTYGTDLHNLKLLVEYQTDERLHVKIYDAEERVYQVPEKVTPRVDSGDGSSKDSALKFEYEEEPFSFTVKRDDEVLFDSSAENLIFQSQYLKLRTWLPENPYLYGLGEHTDPLRLSTTNYTRTFWNRDAYGTSANSNLYGTHPVYYDHRGESGTHGVFLLNSNGMDVFIDKTADGKQYLEYNALGGIFDFYFFTGSNPKEASIEYSKIVGLPAMQSYWTFGLHQCRYGYRDVYQVAEVVYNYTKAGIPLETMWTDIDYMDRRRVFSLDPDRFPLEKMRELVGYLHDHDQHYIVMVDPAVSVSDNGAFNRGLEQDVFLKTQNGSLYKGAVWPGVTAYPDWFHPDIQDYWNSEFSTFFNAETGVDIDGLWIDMNEASNFCPDPCTDPERYSSENNLPPAPPPVRSSSPRPLPGFPADFQPSSASRSQKRIVKAKVGLEGRDLLNPPYKIRNEAGSLSNKTINTGIVHAGEGYAEYDTHNLYGTMMSSSSREAMQYRRPEVRPLVITRSTYAGAGRDVGHWLGDNFSKWEHYRISIAEGLAFASMFQVPMVGADVCGFAGNTTEELCARWASLGAFFTFYRNHNEIGNIGQEFYVWPTVAESARKAIDIRYRLLDYIYTSFYKQSQTGEPFLQPVFYLYPEDENTFSIDLQFFYGDAILVSPVPDKGLTSVDAYFPDDIFYDWYTGTPVRGHGANITLSNIDITHIPLHIRGGSIIPIRSSSAMTTTELREKSFQLIIAPGLDGTASGSLYLDDGDSLEQKATLEVEFEYRKGVLHIDGKFELHASLVESVTLLGQGKGGSRARREDGTKKTIQTNLELSKPTEIKLE
What is the function of this protein?
Glucosidase involved in the degradation of cellulosic biomass.  Has both alpha- and beta-glucosidase activity (By similarity).
What are the official names of this protein?
Probable alpha/beta-glucosidase agdC.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 31 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HUT1_KLULA
Sequence: MGRHILKHVFAVGGIYCSFLTWGLLQEPLNTRVWPNSGCTFQVPYIVALVQATIAMICGLIYIKWQKPVLSLSKFWTSHTRDMAIISLSQAISAPLAAYSLSYVDFLTYMLAKSCKLLPVLMVHLIVYRTPIPRSKKLVVLLVTVGITIFTLDGHKPSMTENDVSESSSSSSLIGFVLLGSSLFLDGLTNAKQDKLFQKATYKITGAHLMFALNFFLIVWNVIYMVLVDRQQLAKGLKMLHADPEISRYLLAYACCGAIGQCFIFYTLEQYGSLVLVMVTVTRKMFSMILSIIVYGHQVTLWQWVGIVIVFTGVVCESMGKKNKAKEGNIINEEKVKQS
What is the function of this protein?
May be involved in specific transport of UDP-Gal from the cytosol to the Golgi lumen.  Involved in the maintenance of optimal conditions for the folding of secretory pathway proteins in the endoplasmic reticulum (By similarity).
What are the official names of this protein?
UDP-galactose transporter homolog 1.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MDTB_ECOLI
Sequence: MQVLPPSSTGGPSRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCARMLSQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQINLKPLDERDDRVQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPQLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIAKIEQRFAPLSINHLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALLIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPREAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALWTKSRFARHEEEA
What is the function of this protein?
The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate.  MdtABC requires TolC for its function.
What are the official names of this protein?
Multidrug resistance protein MdtB, Multidrug transporter MdtB.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OCD_BRUME
Sequence: MMTQPNLNIVPFVSVDHMMKLVLRVGVETFLKELAGYVEEDFRRWQNFDKTPRVASHSKEGVIELMPTSDGTLYGFKYVNGHPKNTRDGLQTVTAFGVLADVGSGYPMLLTEMTILTALRTAATSAVAAKHLAPKNARTMAIIGNSAQSEFQALAFKAILGVDKLRLYDLDPQATAKCIRNLQGAGFNIVACKSVEEAVEGADIITTVTADKANATILTDNMVGAGVHINAVGGDCPGKTELHGDILRRSDIFVEYPPQTRIEGEIQQLPEDYPVNELWEVITGRIAGRKDARQITLFDSVGFATEDFSALRYVRDKLKDTGLYEQLDLLADPDEPRDLYGMLLRHEKLLQSESTKPAA
What is the function of this protein?
Catalyzes the conversion of L-ornithine into L-proline with release of ammonia.
What are the official names of this protein?
Ornithine cyclodeaminase, OCD.
What is the protein family that this protein belongs to?
Belongs to the ornithine cyclodeaminase/mu-crystallin family.
Protein: Y020_PROM4
Sequence: MAAFGLPNFGQLTEAFKKAQQIQQDAQKLQEELDAMELEGKNQDGRVSICLSGNQLPLRIEIDPSILLEGKEKAEIAILEALKDAHELSTSTMKERMQELTGGLNLNLPGIDDGD
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein P9211_00201.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: TULP2_CULQU
Sequence: MEAYIRQKRATPGMVQASDLQLVRPMSAVNRNGREVHAYDGPMQFMMSPSNPDQIISSGSPTTVTATGTTTGSVTTTPTSPYSDATLEKLTPSSQDSEDEESTPVDILPSSNSFDRHSDGHLTHSAPISPALNNNVSRDSQQDSGSSGNLKSMEHSSPQASGHNDAEGDVAGPIEQWVTQPAAQGVLYKCRITRDRKGMDRGLFPIYYLHLERDYGKRLFCLAGRKRKKSKTSNYIISCDPTDLSRQADGFVGKLRSNVFGTTFFVYDNGKKDDPVSPRLDLAVVIYDTNILGFKGPRNMTVLLPGMTEDDQRVKINSSDSHGQGLLDSWKSKHMDNVVELHNKTPIWNDETQSYVLNFHGRVTQASVKNFQLVHDSDPDYIVMQFGRTSDDIFTMDFRYPLCAFQAFAIALSSFDGKLACE
What are the official names of this protein?
Protein king tubby 2.
What is the protein family that this protein belongs to?
Belongs to the TUB family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FUCI_ECOHS
Sequence: MKKISLPKIGIRPVIDGRRMGVRESLEEQTMNMAKATAALLTEKLRHACGAAVECVISDTCIAGMAEAAACEEKFSSQNVGLTITVTPCWCYGSETIDMDPTRPKAIWGFNGTERPGAVYLAAALAAHSQKGIPAFSIYGHDVQDADDTSIPADVEEKLLRFARAGLAVASMKGKSYLSLGGVSMGIAGSIVDHNFFESWLGMKVQAVDMTELRRRIDQQIYDEAELEMALAWADKNFRYGEDENNKQYQRNAEQSRAVLRESLLMAMCIRDMMQGNSKLADIGRVEESLGYNAIAAGFQGQRHWTDQYPNGDTAEAILNSSFDWNGVREPFVVATENDSLNGVAMLMGHQLTGTAQVFADVRTYWSPEAIERVTGHKLDGLAEHGIIHLINSGSAALDGSCKQRDSEGNPTMKPHWEISQQEADACLAATEWCPAIHEYFRGGGYSSRFLTEGGVPFTMTRVNIIKGLGPVLQIAEGWSVELPKDVHDILNKRTNSTWPTTWFAPRLTGKGPFTDVYSVMANWGANHGVLTIGHVGADFITLASMLRIPVCMHNVEETKVYRPSAWAAHGMDIEGQDYRACQNYGPLYKR
What is the function of this protein?
Converts the aldose L-fucose into the corresponding ketose L-fuculose.
What are the official names of this protein?
L-fucose isomerase, 6-deoxy-L-galactose isomerase, FucIase.
What is the protein family that this protein belongs to?
Belongs to the L-fucose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HWP2_CANAL
Sequence: MRFATTQLATLACFILTAEATFPLRGLFNDAPVDVDLGVYHEESGNNKEQKVDGFNMSPNIKKRTNENNAANVVSTNGGLFITSTKELKTTVVVTSCFNNVCSETSITTPKTAVTATTSKHSTSKPTYTTTSKHSTSHSSTPASTSKHSTSTSTHPATSEHSTSKSTHATSSKHSTSKSSVSVTTSKHSTHDTTSKSFVTPPASSTTSEHTKHKSHKPSKTVVTLTSCSNNACSQSEITTGAIVVTDKETVYTTYCPLTDTETETESTTATTSKHSTHTTTSKHSSVESTSVTSSSKHSVSKSTDVTTSKHSSSESSHATTMKHSTSKHSTHATTSKHSTTESTSGITSKHSTHATSSKYSTVESSSSFASTSESSVPVSSSKSTTFESSISTTTSKHLTLKSSTPASTLEYSTSIPPAPATTSNSLSTKSTTLTTISRSSTSGSSVPNTTRESSTSTTTPNSSSSESKVSSAIPKYSSSEVSSSATTLKSYSTTHSIPTTLVYSSSTSLGFSVTEFRNLTTTSKSSLSTSTTELLTSGTTVRSSTSESSVTSATSIYTSSESTTSSESTTSIETPKSIASKSSSSVTLPKSSTFAWSTSTTTPESSPITLKLSTSKPPKPSATMESSASTTKNSSIQSTSEATTSGSSGVESSVLTATTKSSVPVTTSEWSSVVTTPKSSAPNTTLEHSTSASETSSGSVYTTFDQSTTVITVTSCSDNLCSKTEVTTGVTVITSDTTSYTTYCPLTGTTTVSSALESLVTANKSTSYVGATPIVSSVVSTTPIISSASTTPIISSASTTSVISSASTTSVISNAISNPVSTDVKPTTSSQGTKSTPVDTDSKSTSETTVMVYTTKSVTPTTVESISVAVSSAAQSSIAAISSYEGTGNNMKLSFGVVIAGVAAFAI
What is the function of this protein?
GPI-anchored cell wall protein required for mating efficiency, biofilm formation, adhesion, filamentous growth, and oxidative stress tolerance.  Involved in normal disseminated infection in a mouse systemic candidiasis model.
What are the official names of this protein?
Hyphal wall protein 2, GPI-anchored protein 8.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Note=localizes to the cell wall of hyphae.
Protein: TCPN_VIBCH
Sequence: MIGKKSFQTNVYRMSKFDTYIFNNLYINDYKMFWIDSGIAKLIDKNCLVSYEINSSSIILLKKNSIQRFSLTSLSDENINVSVITISDSFIRSLKSYILGDLMIRNLYSENKDLLLWNCEHNDIAVLSEVVNGFREINYSDEFLKVFFSGFFSKVEKKYNSIFITDDLDAMEKISCLVKSDITRNWRWADICGELRTNRMILKKELESRGVKFRELINSIRISYSISLMKTGEFKIKQIAYQSGFASVSYFSTVFKSTMNVAPSEYLFMLTGVAEK
What is the function of this protein?
Probable regulatory protein for the tcp operon.
What are the official names of this protein?
TCP pilus virulence regulatory protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SGT2_SCHPO
Sequence: MSSNKVTAAIIDYLKQAITTGSISEEEKESLEVAAQCIQDSFKIKPEEIKPKSGDRLVAAFEEYEKLHPVEEDSTAHVNKEEAEKLKLEGNNAIAAKDYQKALDLYTKAIEIDPTSPVYYSNRAAAYNQLGQFENAVEDALTCLSLDPHHARAFGRLGRAKLSLGDAAAAADAYKKGLDFDPNNEVLKRGLEAANKQLNQPSDSSATSGADQARTSAGAAPDLGSIFGGGMPDLGSLMNNPAVMNMARNLMQSGALNNIMNDPNIANMARNFQSGGGMPDLSSLANNPQLQNLARNFMNNNNNGNTDNNNQGNPPPQ
What is the function of this protein?
Co-chaperone that binds to the molecular chaperone Hsp70 and regulates Hsp70 ATPase activity.
What are the official names of this protein?
Small glutamine-rich tetratricopeptide repeat-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the SGT family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RAD9A_MACFA
Sequence: MLGKAVHSLSRIGDELYLEPLEDGLSLRTVNSSRSAYACFLFAPLFFQQYQAATPGQDLLRCKILMKSFLSVFRSLAMLEKTVEKCCISLNGRSSRLVVQLHCKFGVRKTHNLSFQDCESLQAVFDPASCPHMLRAPARVLGEAVLPFPPALAEVTLGIGRGRRVILRSYHEEEADSTAKAMVTEMCLGEEDFQQLQAQEGVAITFCLKEFRGLLSFAESANLNLSIHFDAPGRPAIFTIKDSLLDGHFVLATLSDTDSHSQDLGSPERHQPVPQLQAHSIPHPDDFANDDIDSYMIAMETTIGNEGSRVLPSISLSPGPQHPESPGLHSEEDEAEPSTVPGTPPPKKFRSLFFGSILAPARSPQGPSPVLAEDSEGEG
What is the function of this protein?
Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair.  The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex.  Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER).  The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths; and DNA ligase I (LIG1) on long-patch base excision repair substrates.  The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase.  RAD9A possesses 3'->5' double stranded DNA exonuclease activity (By similarity).
What are the official names of this protein?
Cell cycle checkpoint control protein RAD9A, DNA repair exonuclease rad9 homolog A.
What is the protein family that this protein belongs to?
Belongs to the rad9 family.
What are the subcellular locations of this protein?
Nucleus.