PharMolix/UniProtQA huggingface dataset:
Protein: AROC_STAAS
Sequence: MRYLTSGESHGPQLTVIVEGIPANLEIKVEDINKEMFKRQGGYGRGRRMQIEKDTVEIVSGVRNGYTLGSPITMVVTNDDFTHWRKIMGAAPISEEERENMKRTITKPRPGHADLVGGMKYNHRDLRNVLERSSARETAARVAVGALCKVLLQQLDIDIYSRVVEIGGIKDKDFYDSKTFKANLDRNDVRVIDDSIAQAMRDKIDEAKNDGDSIGGVVQVVVENMPVGVGSYVHYDRKLDGRIAQGVVSINAFKGVSFGEGFKAAEKPGSEIQDEILYNTELGYYRGSNHLGGLEGGMSNGMPIIVNGVMKPIPTLYKPLNSVDINTKEDFKATIERSDSCAVPAASIVCEHVVAFEIAKALLEEFQSNHIEQLKQQIIERRQLNIEF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: PFKA_THEPX
Sequence: MKTIGILTSGGDAPGMNAAIRAVVRTGIYYGLKVKGIMRGYAGLVEDEVIDLNLSSVGDILQKGGTILRTARCEEFKKKEVRKKAYETLQKHGIEGLVVIGGDGSFRGAQLLSEEWNVNTIGIPGTIDNDIPCTDYTIGFDTACNTVIDAINKIRDTATSHERANIIEVMGRNAGYIALYAGLAGGAEMIILPEVEWSIDELCDKITYGIKRGKLHHIIVLAEGVMSAPELAKMIKERLPKLDLRYTILGHIQRGGAPTVMDRVLASQMGARAVELLLENKTKRIISIRNNQIVDDDIDEALSMKKEFNRKLYELSKILSI
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU31_BORBR
Sequence: MSEQNRLLLIGGDGVGAEVVHEAGRIAQWFAARRGLPLSIGQAAFGVEVLNRTGRIMTDDTLAQIRAADAVLFGAIGGPEYDRLPLEQVREEGLLRIRRELGLYANLRPVRYWPALAELCPFVPERVEKVDMMIVRELAGGIYYASPRGIDQTGDGRRVGTNTQRYDDLEIRRIARVAFELARARGGRVCSVDKSNVLESGLLWREEVQACRDAEYPDVELEHILVDNCALQLCLRPARFDVLLADNLFGDILSDAAGAVAGSLGMLPSASFGAEDGGRRRGFYEPVHGSAPDIAGQGIANPLGAILSLALALRWTFRQPAEADLLERAVERALAGGARTLDLLAGAAAPALSTRAMADAVLQALETLAA
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase 1, 3-IPM-DH 1, Beta-IPM dehydrogenase 1, IMDH 1.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_NITWN
Sequence: MNQEVMNLFNPTTPAQVFDQIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMKYKGIICEKCSVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRIGLLLDMTLKDLERILYFEYYVVLEPGLTALKDRQLLSEEEYLRAQDEYGQDSFTAMIGAEAIRELLKGLELERLEAELRAEMQATESDIKHKKLAKRLKIVEAFRFSGNKPEWMILTVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELRAPDIIIRNEKRMLQEAVDALFDNGRRGRVITGANKRPLKSLADMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKKMALELFKPFIYSRLDAKGLSTTVKQAKKLVEKERPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPTLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQLEARVLMMSTNNILHPANGQPIIVPSQDIVLGLYYLSIMREGLPGEGKVFGDMAELEHALHSGVIHLHTSIKYRWDQTDENGEPIKRLIDTTAGRVMLGQVLPKSQKISFDAINKLMTKREISGVIDQVYRHCGQKETVIFCDRIMALGFYNAFKAGISFGKDDMVVPHGKWKIVDTTRALAKDFEQQYNDGLITHGEKYNKVVDAWSKATEEIAKEMMKEISSTKKDAKGIEAQINSIYMMAHSGARGSPAQMRQLAGMRGLMAKPSGEIIETPIISNFKEGLSVLEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDCIITQDDCGTKLGIKMRAIVDAGTVVASLGSRILGRTACEDIRNPASNEVLIERNTLMEESHVDQISKAGIQEVKIRSALTCELINGICGKCYGRDLARGTPVNHGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQINEQSVIESNFDGKITIRNKAIARNGEGHLVAMVRNMVVAVVDADGTERATHRIQYGARMHVDEGDMVKRGQRIAEWDPYTRPVLTELEGTIGFEDLIEGQSISETLDESTGIAKRIVIDWRGTRGGADLRPAIVIKGKDGKVLKLPRGGDARYMLSVDAILSVDVGAKVKPGDILARISTESAKTRDITGGLPRVAELFEARRPKDAAIIAEIAGTIRFGRDYKNKRRISIEPVDQEEETREYLIPKGKHIHLQDGDIVEKGDFIVDGNPAPHDILAIKGIEELAAYLVNEIQEVYRLQGVLINDKHIEVIVRQMLQKVEIIDQGETDMISGEQIDKIEFDRLNLKAQEEGKKIATGTPVLLGITKASLQTRSFFSAASFQETTRVLTEAAVNGKVDPLEGLKENVIVGRLIPAGTGASMAKIREVAVKRDRLILDEREKQAAIVPSAPEAEPLALPPAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: ZFY27_MOUSE
Sequence: MQTSDRDLSGPEASPSGMPEVLSECPPAPTKSAAFDLFNLVLSYKRLEIYLEPLKDAGDGVRYLLRWQMPLCSLLTCLGLNILFLTLNEGAWYSMGALMISVPALLGYLQEVCRGQLPESELMRRKYHSIRQEDLQRVRLSRVHLSRPEAVAEVKSFLIQLEAFLARLCYTCESAYRVLHWENPVVSSQFYGALLGMVCMLYLLPLCWVLALLNSTLFLGNGDFFRVVCEYRACLQRRMNPRQEECACESSALQGAGGRGLLDSSPAPTPTEDLTPGSVEEAEEAEPDEEFKDAIEETHLVVLEDEEGTPCPAEDELTLQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCAGCAATFSVLKKRRSCSNCGNSFCSRCCSFKVPRSSMGATAPEAQRETVCVCASCNQTLSK
What is the function of this protein?
Key regulator of RAB11-dependent vesicular trafficking during neurite extension through polarized membrane transport (By similarity).  Promotes axonal elongation and contributes to the establishment of neuronal cell polarity (PubMed:24251978).  Involved in nerve growth factor-induced neurite formation in VAPA-dependent manner.  Contributes to both the formation and stabilization of the tubular ER network.  Involved in ER morphogenesis by regulating the sheet-to-tubule balance and possibly the density of tubule interconnections (By similarity).  Acts as an adapter protein that facilitates the interaction of KIF5A with VAPA, VAPB, SURF4, RAB11A, RAB11B and RTN3 and the ZFYVE27-KIF5A complex contributes to the transport of these proteins in neurons.  Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a KIF5A/B-dependent manner (PubMed:21976701).
What are the official names of this protein?
Protrudin, Zinc finger FYVE domain-containing protein 27.
What are the subcellular locations of this protein?
Recycling endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell projection, growth cone membrane; Multi-pass membrane protein. Note=Localizes at both dendrites and axons (PubMed:17082457). Localizes to endoplasmic reticulum tubular network.
Protein: RS8_YERPN
Sequence: MSMQDPIADMLTRIRNGQAANKVAVTMPSSKLKVAIANVLKEEGFIEDFKIEGDTKPVLELALKYFQGKAVVESIQRISRPGLRIYKKKDELPKVMAGLGIAVISTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RL9_DICNV
Sequence: MEIILLDRVHGLGSLGDKVRVKSGYARNYLIPNGKATEAIPSKIAEFEARRKELEEKQAQRLAASAQRAESLNGKILTVFAKAGDEGKLFGSVGTQQIVAAAEQQGLQLERQEVMMPHGTIRELGEYVVDLKLYGDIEAQVTVRVVVAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: LDH_THECA
Sequence: MKVGIVGSGMVGSATAYALALLGVAREVVLVDLDRKLAQAHAEDILHATPFAHPVWVRAGSYGDLEGARAVVLAAGVAQRPGETRLQLLDRNAQVFAQVVPRVLEAAPEAVLLVATNPVDVMTQVAYRLSALPPGRVVGSGTILDTARFRALLAEHLRVAPQSVHAYVLGEHGDSEVLVWSSAQVGGVPLLEFAEARGRALSPEDRARIDEGVRRAAYRIIEGKGATYYGIGAGLARLVRAILTDEKGVYTVSAFTPEVEGVLEVSLSLPRILGAGGVEGTVYPSLSPEEREALRRSAEILKEAAFALGF
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_METFK
Sequence: MEDIKHYMQQLGSEARTASRAMARADTETKNKALRAIATAIRRERDTLLAANAADLEAARRHGLEPAMLDRLVLSEKGIDTMAEGLEQIAGLPDPIGEMSDFKYRPSGIQIGKMRVPLGVIGIIYEARPNVTVDAAGLCIKSGNAAILRGGSEAIQCNRALAAIVHEGLAAAALPASAVQVVATTDRAAVGELITMKDYVDVIVPRGGKGLIERISNEARIPVIKHLDGNCHVYIDESADLAKALRILENSKTQRLGTCNTAESLLVARSIAQEALPPLTAMLISKGVEIRGCSETRALVPQAKPATEEDYYTEYLAAIISVKVVADVDEAIAHINQYSSQHTEAIVTENYTNARRFLREVDSSSVIVNASTRFADGFEYGLGAEIGISTDKLHARGPVGLEGLTSLKYIVLGDGEVRA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSK_ASPOF
Sequence: MSSKAITLLLIALLFSLSLAQAARPLQPADSTKSVHVIPEKVHDEACEGVGEEECLMRRTLTAHVDYIYTQDHNP
What is the function of this protein?
Promotes plant cell differentiation, organogenesis and somatic embryogenesis as well as cell proliferation.
What are the official names of this protein?
Phytosulfokines.
What is the protein family that this protein belongs to?
Belongs to the phytosulfokine family.
What are the subcellular locations of this protein?
Secreted.
Protein: UBCX_PICAN
Sequence: MSSTEKRLLKEYRAVKKELTEKRSPIHDTGIVDLHPLEDGLFRWSAVIRGPDQSPFEDALWKLEIDIPTNYPLDPPKIKFVVFGEEKIRQLQRKTSSGARKVCYKMPHPNVNFKTGEICLDILQQKWSPAWTLQSALVAIVVLLANPEPLSPLNIDMANLLKCDDTTAYKDLVHYYIAKYSAYESNDV
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.  Essential for peroxisome biogenesis.  Required for UBC4-independent ubiquitination of PEX5.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2-21 kDa, E2 ubiquitin-conjugating enzyme PEX4, Peroxin-4, Ubiquitin carrier protein, Ubiquitin-protein ligase.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: ATPE_HALOH
Sequence: MPSTIRLEVVTPEKVVFSEPVNILIAPAIDGEIGILPKHTPLVTGLKTGVMRVKKDGEEVKISISEGFMEVKPDEINVIVRTAELPHEIDVERARDALKRAEKRLNSRNDRIDRARARAAFERAIARLKAAGHY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: BGAL_ECOLC
Sequence: MTMITDSLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEARTDRPSQQLRSLNGEWRFAWFPAPEAVPESWLECDLPEADTVVVPSNWQMHGYDAPIYTNVTYPITVNPPFVPTENPTSCYSLTFNVDESWLQEGQTRIIFDGVNSAFHLWCNGRWVGYGQDSRLPSEFDLSAFLRAGKNRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHKPTTQISDFHVATRFNDDFSRAVLEAEVQMCGELRDYLRVTVSLWQGETQVASGTAPFGGEIIDERGGYADRVTLRLNVENPKLWSAEIPNLYRAVVELHTADGTLIEAEACDVGFREVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSHYPNHPLWYTLCDRYGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRNHPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVQYEGGGADTTATDIICPMYARVDEDQPFPAVPKWSIKKWLSLPGETRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQGGFVWDWVDQSLIKYDENGNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQQQFFQFRLSGQTIEVTSEYLFRHSDNELLHWMVALDGKPLASGEVPLDVAPQGKQLIELPELPQPESAGQLWLTVRVVQPNATAWSEAGHISAWQQWRLAENLSVTLPAASHAIPHLTTSEMDFCIELGNKRWQFNRQSGFLSQMWIGDKKQLLTPLRDQFTRAPLDNDIGVSEATRIDPNAWVERWKAAGHYQAEAALLQCTADTLADAVLITTAHAWQHQGKTLFISRKTYRIDGSGQMAITVDVEVASDTPHPARIGLNCQLAQVAERVNWLGLGPQENYPDRLTAACFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNISRYSQQQLMETSHRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVWCQK
What are the official names of this protein?
Beta-galactosidase, Beta-gal, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
Protein: NOVJ_STRNV
Sequence: MTSPADATTEVAVSQESVAMVTGAGRGIGAATAERLAAEGMAVIVVDRTEQDTRATVAAIRTAGGRARGIGCDVAVAQAVTAAVATAVEEFGRIDVLVNCAGINRDRLLLTMGDQEWDTVLDVNLGGTMRCSFAVGRHMRRQGHGRIINFSSVAARGNAGQTNYATAKGAIAGFTRTLAAELGPHGVTVNAIAPGFVATPMVDELAERLGGDRDSVMSEAAKSSAVGRIGTPEEIAATVVFVARPESGYLTGETVHVDGGRP
What is the function of this protein?
Catalytic subunit of the NovJ(2)K(2) heterotetramer that catalyzes the NADPH-dependent reduction of the tyrosyl moiety of L-beta-OH-Tyr-S-NovH intermediate to yield the tethered beta-ketotyrosyl-S-NovH in the novobiocin biosynthesis pathway.  Novobiocin is an aminocoumarin family antibiotic that targets bacterial DNA gyrases.
What are the official names of this protein?
Short-chain reductase protein NovJ, Novobiocin biosynthesis protein J.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: LIP_BURPL
Sequence: MVRSMRSRVAARAVAWALAVMPLAGAAGLTMAASPAAVAADTYAATRYPVILVHGLAGTDKFANVVDYWYGIQSDLQSHGAKVYVANLSGFQSDDGPNGRGEQLLAYVKQVLAATGATKVNLIGHSQGGLTSRYVAAVAPQLVASVTTIGTPHRGSEFADFVQDVLKTDPTGLSSTVIAAFVNVFGTLVSSSHNTDQDALAALRTLTTAQTATYNRNFPSAGLGAPGSCQTGAATETVGGSQHLLYSWGGTAIQPTSTVLGVTGATDTSTGTLDVANVTDPSTLALLATGAVMINRASGQNDGLVSRCSSLFGQVISTSYHWNHLDEINQLLGVRGANAEDPVAVIRTHVNRLKLQGV
What is the function of this protein?
Catalyzes the hydrolysis of triacylglycerol.
What are the official names of this protein?
Triacylglycerol lipase, Extracellular lipase, Triacylglycerol ester hydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Pseudomonas lipase family.
What are the subcellular locations of this protein?
Secreted. Note=Correct periplasmic folding, necessary for secretion, requires the lipase-specific foldase LifO (also called lipB). Secretion probably occurs via a type II secretion system.
Protein: TRPC_SYNSC
Sequence: MEIRRRPPNPKVRVAHLEYAVPHDDEEPRHILEKIVWEKDREIDAARDKVPLDNLKQQIAKLPPTKDFLGALQAAATKPAVIAEVKKASPSKGVIREDFDPVAIAKAYASGGASCLSVLTDKTFFQGGFDVLVEVRQAVDLPLLCKEFVLSPYQLFQARAAGADAVLLIAAILSDQDLRYLNKAAAALGLTVLVEVHDATEMDRVLSIGGFPLIGINNRDLTSFETDLATTERLLVDFNDRLKQQGVLLVSESGLFSRADLDRVQAAGAGAVLVGEALMRQQDVEAGLVQLIQAG
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: PYRC_NOVAD
Sequence: MTETLTIRRPDDWHVHLRDRDVLRGVVPYTARQFARAIVMPNLSPPMTDVAGVAAYRDRILAALPQGSAFTPLMTLYLTDSTDIEEVARGFAEGVFVAAKLYPAHATTGSAHGVTDIRNIYPVLEKMQEIGMPLLIHGEVTDSHVDIFDREAVFIERTLTRLVADMPALRIVFEHITTEEAAQFVEGAGDSIAATITPQHLHINRNAMLVGGIRPHAFCLPVAKREKHRLALRKLATSGFSRVFLGTDTAPHAKHLKEAACGCAGIFNAPFALESYVTVFDEEGALDRFEAFASLNGPAFYRMPVNEDRIVLERAPIEVPEVIDCNGTAIVPFHAGETLGWRIAAA
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: DDL_MOOTA
Sequence: MKIAVLMGGPSSEREISLKSGSAVAAALSGLGHQVITIDLNREVVARLKNFAPDVVFNALHGKPGEDGSVQGLLEVLGLPYTGSRVLASAITMDKIMTKRVLLQAGIPTPKFLAWTGAEYATGKKEIKAAILKELGLPVVIKAPTQGSTIGTFIVREEGELEPAIAGALKYDLSFMAEAYLAGPEITAAVLGNRKPQVLPLIEIVSHTGFYDYQAKYTPGLSDHIIPPRLPDDVLAAATSLAGRTYALLGCRGFARVDFIVAGGREPQVIEVNSVPGMTATSLVPDAARAAGLDFPDLVQKIVDLALEP
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAJI_ECOLI
Sequence: MNTNVFRLLLLGSLFSLSACVQQSEVRQMKHSVSTLNQEMTQLNQETVKITQQNRLNAKSSSGVYLLPGAKTPARLESQIGTLRMSLVNITPDADGTTLTLRIQGESNDPLPAFSGTVEYGQIQGTIDNFQEINVQNQLINAPASVLAPSDVDIPLQLKGISVDQLGFVRIHDIQPVMQ
What are the official names of this protein?
Uncharacterized lipoprotein YajI.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: PSD10_RAT
Sequence: MEGCVSNLMVCNLAYNGKLDELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNEKDDAGWSPLHIAASAGRDEIVKALLIKGAQVNAVNQNGCTALHYAASKNRHEIAVMLLEGGANPDAKNHYDATAMHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHLACDEERVEEAKLLVTQGASIYIENKEEKTPLQVAKGGLGLILKRIAESEEASM
What is the function of this protein?
Acts as an oncoprotein by being involved in negative regulation of tumor suppressors RB1 and p53/TP53.  Overexpression is leading to phosphorylation of RB1 and proteasomal degradation of RB1.  Regulates CDK4-mediated phosphorylation of RB1 by competing with CDKN2A for binding with CDK4.  Facilitates binding of MDM2 to p53/TP53 and the mono- and polyubiquitination of p53/TP53 by MDM2 suggesting a function in targeting the TP53:MDM2 complex to the 26S proteasome.  Involved in p53-independent apoptosis.  Involved in regulation of NF-kappa-B by retaining it in the cytoplasm.  Binds to the NF-kappa-B component RELA and accelerates its XPO1/CRM1-mediated nuclear export (By similarity).
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 10, 26S proteasome regulatory subunit p28, Gankyrin.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HLDE_CAUVC
Sequence: MDDALAHLPRAFAGKTVLVLGDVMLDRFIYGAVDRISPEAPVPVIAVEKETAMLGGAGNVARNVAALGAKAVLIGLVGRDDAGAALRGMIDAEAGLEAELVVDPARRTTEKVRYISGSHQMLRVDREDRSPGDGAALLAAFETRLASADVVVLSDYAKGVLTPAVVRGAIDAAKAAGKPVIVDPKSRDFARYDGATLIKPNRKEAAEATGIVETSDAASEDAGAAILAMAPGLQAALITRGGAGMTLAVRNQPPIHLPATAIEVFDVSGAGDTVAATLALAVAAGASLAQAAQLANLAGGLVVAKLGTDVVTAAELTACASSAQGEPGEIKIADREQAQRIVEGWRARGLKVGFTNGCFDLLHPGHVSLLSQAKAACDRLIVGLNTDASVSKLKGPTRPVQKEQGRATVLASLSSVDLVVLFDEDTPLELIKAFRPDVLVKGADYTVETVVGSDVVLGYGGKVVLAELKQGQSTTNLIARMNS
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: RL16_FRAT1
Sequence: MLQPKRTKFRKQQKLRNRGLAHRGNKVSFGEFGLQATSRGRITARQIEAGRRAISRHIKRGGKIWIRIFPDKPITQKPLEVRMGKGKGSVEYWVAQIQPGRVLYEITGVKEELAREAFARAAAKMPVQTTFVEKQVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: KTHY_THESQ
Sequence: MFITFEGIDGSGKSTQIQLLAQYLEKRGKKVILKREPGGTETGEKIRKILLEEEVTPKAELFLFLASRNLLVTEIKQYLSEGYAVLLDRYTDSSVAYQGFGRNLGKEIVEELNDLATDGLIPDLTFYIDVDVETALKRKGELNRFEKREFLEHVREGYLVLAREHPERIVVLDGKRSIEEIHRDVVREVERRWKLDV
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: NUOCD_BACFR
Sequence: MEEIKYIEPAALHDEMLRLRNEKQMDFLESLTGMDWGVADEGDAPNVTRGLGVVYHLESTVTGERIAIKTSTNNRETPEIPSVSDIWKAADFNEREVFDYYGIVFIGHPDMRRLYLRNDWVGHPMRKDNNPEKDNPLRMDNEETYDTTREIELNPDGTYQTQENVIFDDREYVVNIGPQHPATHGVMRFRVSLEGETIKKLDANCGYIHRGIEKMNESLTYPQTLALTDRLDYLGAHQNRHALCMCIEKAMGIEVSERVKYIRTIMDELQRIDSHLLFYSCLAMDLGALTAFFYGFRDREMILDMFEETCGGRLIMNYNTIGGVQADLHPNFIPRVKKFIPYLRGIIHEYHDVFTGNVIARQRLKGVGVLSREDAISFGCTGGTGRASGWACDVRKRMPYGVYDKVDFKEIVYTEGDSFARYMVRMDEIMESLNIIEQLIDNIPEGPIQEKMKPIIRVPEGSYYTAVEGSRGEFGVFLESHGDKTPYRLHYRSTGLPLVSAVDTICRGAKIADLIAIGGTLDYVVPDIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y9392_DICDI
Sequence: MSQIFKERNHFYIRICEGYVLPLLLILHDHQYFNNIQFLELITVLQGIIRNHFKNGMGLRSTYIAPESASTSKPIYLSDIGFTIRFAPTYPRYSIMVKNIKPQENRNEPIKIKRKETIYIDNKVKDSINNSNNNNNKKDKKDKNKQNEEDHLIIDDVIDEEIQEKEDNESDSDKKKLITKITTTTTTTIPTSSPTNIIDDNVEVIETRFDKEEKEREKEKEKEKEKEEKEEDIDILNDRAIALAATQEYEDDDVIFIKDDNDNDKNQNQNQNQNNNNNNNNNNNNNNNNNNNNEGEEEDEELPYQGGMYKGLYVTGHTMIVETQIKVAGATTLISQFHVANEDKDADDSDDFDEFNLPDTESQLSKSKQKSPNVKKTTTTTTTSTSTSSRKQSKSKLKPKSKSTMATNNGGISLYFKK
What are the official names of this protein?
Putative uncharacterized protein DDB_G0288959.
Protein: IF2_ALISL
Sequence: MTKLTVKALSEDIGTPVDRLLQQFSDAGINKKDGDSVSEGEKQSLLIHLKKEHGSADESASPTRLTLQRKTRSTLSVAGSGGKSKDVQVEVRKKRTYVKASTLEEEKKTEQMKVEAGDKAKRDAEEAAVRELEQKAKREAEEKAKREAEAEVKVKRDAEQTAKRTKTEKAKKEMTTKNDQAKTEADELKLRQETEATRKAEAEAAKLVEDARKLAEENEGRWKEEEQKKTAAEKTADYHVTTSTHAREAEDAADRKDEQQPRRRKKKAKAAPVERGGRNQRGGRNRKPQVNKPTSMQHGFDKSATVAKQDVAIGETIIVSELANKMSVKATEVIKVMMKMGAMATINQVIDQETAALVAEEMGHKVVLRKENELEEAVLSDRDNSATVEGRAPVVTIMGHVDHGKTSTLDYIRRAHVADAEAGGITQHIGAYHVETDNGMITFLDTPGHAAFTAMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAGVPLIVAVNKIDKEGANPDNVKNELAQYDIIPEEWGGENMFVHISAKQGTNIEGLLEAILLQSEVLELTAVKEGMASGVVVESRLDKGRGPVATVLVQSGTLHKGDIVLCGQEYGRVRAMRDENGKDIDSAGPSIPVEILGLSGVPASGDEATVVRDERKAREVANYRQGKFRDVKLARQQKAKLENMFANMEAGEVAECNVVLKADVQGSVEAIADSLRKLSTDEVKVNIVGSGVGGITETDATLAAASNAILLGFNVRADTSARRTIENENLDLRYYSIIYQLIDEVKQAMGGMLAPEFRQEIIGLAQVREVFKSPKIGAVAGCMVTEGTIKRNNPIRVLRDNIVIYEGELESLRRFKDDMPEVKNGYECGIGVKNYNDVRVGDQIEVFEIVEIQRTLD
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLGC_STAAW
Sequence: MLKNKILATTLSVSLLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQNIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKTNDKYVSLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSFNYSKSISYTQQNYVSEVEQQNSKSVLWGVKANSFATESGQKSAFDSDLFVGYKPHSKDPRDYFVPDSELPPLVQSGFNPSFIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHNAFVNRNYTVKYEVNWKTHEIKVKGQN
What is the function of this protein?
Toxin that seems to act by forming pores in the membrane of the cell.  Has a hemolytic and a leucotoxic activity (By similarity).
What are the official names of this protein?
Gamma-hemolysin component C.
What is the protein family that this protein belongs to?
Belongs to the aerolysin family.