PharMolix/UniProtQA huggingface dataset:
Protein: NAMA_LISMF
Sequence: MSKLFSEYKLKDVTLKNRIVMSPMCMYSVENKDGIATDFHFAHYVSRAAGGTGLVILEATAVQEVGRISEFDLGLWNDEQVPALKKLVDGLHYHGAKAGIQLAHAGRKAVLPGEIVAPSAIAFDEKSDKPVELTKEAIKEVVADFKRAAYRAKEAGFDVIEIHAAHGYLIHQFLSPITNRREDNYGGPAGNRYKILSDIIKAVKEVWDGPIIVRVSATDYAHGGLQLEDHIPFAKWMKADGVELIDVSTGGLVNVAPPVFPGYQVPFADEIRRGAGIATGALGLITRGEQAEEILCNERADLIIVGRELLRNPYFAKDAAKQLGETIEGPKQYSRAWK
What is the function of this protein?
Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones.  It also reduces the nitro group of nitroester and nitroaromatic compounds.  It could have a role in detoxification processes.
What are the official names of this protein?
NADPH dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily.
Protein: KDPA_RIPO1
Sequence: MVQGLIQIAITLLLLLIIVPNLGNYMAKVYLKQKTVLDPILLPLENLIYAISGLRSQREMTGWQYARSVIFSNILMGIFVFSLFSFQAILPFNPTQLAAPSWHLALHTTISFVTNTNQQHYSGETTFSYGSQLFALGFLMFTSAGTGLAVAMAFIRGLIGEPLGNFYVDLTRSITRILLPIALISGLILLSQGVPETLSPPASVTTLQGATQTLARGPVAHFESIKQLGENGGGFFGINSAHPFENPNGFSNLIETLLMLCIPTSLIYTYGVMIGNKKQAWLLFSMIFIIYVFLIAITALGEYQGNPLVNNLLTTQQPNLEGKEIRFGWAQTVLWAISTTGTMCGAVNGMHDSLMPLGGLSTLFNLFLQIIWGGQGTGTAYLFVFLIITVFLTGLMVGRSPEFLGRKIEKREIVFASVILLVHPFAILVPGAITLVFPEILSGISNPGFHGVSQVVYEYASAAANNGSGFEGLGDNTLWWNLSTSVVLLLGRYVPIIALLLLAESMRQKQPVPETTGTLRTDTGLFTAVTAGVILILGALTFLPVLALGPIAEGFKLGW
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MACO1_CAEEL
Sequence: MMQQQKPGKPKKINRIDKIKRLQINRSRRPDINQTVPSPLFYVRIVVTWLGMVSLDAMTGFRFELLWPTWLMIRAAAESIQMRNQHCVTTIANPTAARFSVLFICVTATSDLICYLFIPIRMLIFLATTYVWISLYYHTQGGFLRSLATVYGGERLQSWPIVFITCFIVIFELFLRIRSHPILISFFPNVAEYAGVSPVWPRSLNAFFGAHSIGYPVILITVSMHYYFNEWKLRRKQCDVSNRNEQLFRILVEGLPAEYEGPKDYTSQQCLEDDLYYLDPPVQTLQPMQAIQAASATPPTSSKKNGIHKRNGDVTSSTTTSSRKKKHNGNSGFNSTPPNDKKKGKSIRDVDMDDGDDSDDDYSYRDTSSSTIEDQRRGGGISIIRFIFSSAAWLFSFVFESSTPSENSLSNQQIDDDEDYEDGDGDKKNGRTDSMTSTTKGRANTMPSTTRSQNNNNSQKQQKQSNGKSHHQHSSHQNNHQKSNGNSNGHARGFAAVRDSSHDTNASNETDIRSMSRELESLRSEISSRRSQEEDFKLQVSMHESNETRLSQQLSNMRLKVEQMEIKCSSIERHRESDKHQLEQAERKYADLLGKKAEIEATLSAERKARMEVTSKKYDVAEHQRERERQLESEIDKLRIELKSKDESNMRMESELHGLRNYKEENDIDSLNMELRFVRDKSHQMEESLAGENKLKQSLFKCLGDARDTIKSLERRVQEFQIKNGSSIGGGSSETLMNGRSSTEANNENDTTASDQSSPHQHSAMGSPVPFAKMPLSVNVSNRHGSPFNGKVSPIASIGSVLAAAGGPAPPDYMMAVGANVTATTGPVPQKQPRAGFHGISRYNEFTNIASGGEHRLFDTPASAISASAINGSNPEDDFLMNKGKFGAPSQPAARLA
What is the function of this protein?
Plays a role in the regulation of neuronal activity.  In AWA and AWC neurons, plays a role in regulating olfactory adaptation by controlling the forgetting sensory responses to odorants such as diacetyl and isoamyl alcohol (PubMed:28924007).  May play a role in regulating daf-7 expression in ASI neurons in response to bacterial small RNAs (PubMed:32908307).  In ASI neurons, promotes dauer formation in response to pheromones such as the ascarosides ascr#2 and ascr#3 (PubMed:26976437).
What are the official names of this protein?
Macoilin.
What are the subcellular locations of this protein?
Rough endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein. Note=Restricted to neuronal cell bodies, absent from dendrites and axons (PubMed:21437263).
Protein: SYA_PROM3
Sequence: MAVARSLRSGESGPRTGSEIRTAFLTFFAERAHQVIPSASLVPEDPTVLLTIAGMLPFKPVFMGQAERPAPRATSSQKCIRTNDIENVGRTARHHTFFEMLGNFSFGDYFKQQAIEWAWELSTEVFGLNPKNLVVSVFREDDEAEAIWRDVVGVNPKRIIRMDEADNFWASGPTGPCGPCSEIYYDFKPDLGNDDIDLEDDGRFVEFYNLVFMQYNRDGEGNLTPLANRNIDTGMGLERMAQILQGVPNNYETDIIYPLIETAAGLAGLDYQKLDDKGKTSFKVIGDHCRAITHLICDGVTASNLGRGYIMRRLLRRVVRHGRLVGIEKPFLQAMGEAAIALMVEAYPQLEERRKLILAELNREEARFLETLERGEKVLADVLVANPQMISGGQAFELYDTYGFPLELTQEIAEEHGLTVDLQGFEQAMDQQRQRAKAAAVSIDLTLQGAIEQMAAELEATRFKGYQVLEQPCCVLALVVNGESAERASAGDNVQIVLDTTPFYGESGGQVGDHGVLSGEGSGGNGVIVAVDDVSRHRNVFVHFGRIERGTLALGDLVNAQVDRACRRRAQANHTATHLLQAALKQVVDSGIGQAGSLVDFDRLRFDFHCSRAVTAKELEQIEALINGWIMESHDLIVEEMSIQEAKAAGAVAMFGEKYADVVRVVDVPGVSMELCGGTHVANTAEIGLFKIVAESSVAAGIRRIEAVAGPAVLAYLNERDVVVKELGDRFKAQPSEIIERVISLQEELKSSQKALTAARAELAVAKSAALATQAVAVGEYQLLVARLDGVEGAGLQNAAQGLLDQLGDATAVVLGGLPDPSDEGKVILVAAFGKQVIAQGQQAGKFIGSIAKRCGGGGGGRPNLAQAGGRDGAALDGALEAAKVELKQSLG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRI15_PANTR
Sequence: MPATPSLKVVHELPACTLCAGPLEDAVTVPCGHTFCRLCLPALSQMGAQSSGKILLCPLCQEEEQAETPMAPVPLGPLGETYCEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVGFLDEAIQPYRDRLRSRLEALSMERDEIEDVKCREDQKLQVLLTQIESKKHQVETAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQQPASELLQDVRVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSENLAHHLEIDSGVITLDPQTASRSLVLSEDRKSVRYTRQKKNLPDSPLRFDGLPAVLGFPGFSSGRHRWQVDVQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQCWASTSPGTDLPLSEIPRGVRVALDYEAGQVTLHNAQTQEPIFTFTASFSGKVFPFFAVWKKGSYLTLKG
What is the function of this protein?
E3 ubiquitin ligase that plays a role in several processes including innate antiviral immnity, cell migration and chemotaxis.  Acts as a 'Lys-63'-specific ubiquitin ligase for MAPK1/ERK2 and MAPK3/ERK1, promoting their activation by facilitating their interaction with MAP2K1 and MAP2K2.  Plays also a role in cell migration and chemotaxis by acting as a stable focal adhesion component upon recruitment by multi-adapter protein paxillin/PXN.  Functions in the RIGI-mediated interferon induction pathway upstream or at the level of MAVS.  Inhibits NF-kappa-B activation by turnover of 'Lys-63'-linked ubiquitination of MAP3K7/TAK1.  Mechanistically, prevents TRIM8 cytoplasmic translocation and thus inhibits TRIM8-mediated 'Lys-63'-linked polyubiquitination of MAP3K7/TAK1 in the cytoplasm.  Plays also an important regulatory effect on the activation of hepatic stellate cells (HSCs).
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM15, Zinc finger protein B7.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
Protein: GALP_MOUSE
Sequence: MACSVHLVLFLTILLSLAETPESAPAHRGRGGWTLNSAGYLLGPVLPVSSKADQGRKRDSALEILDLWKIIDGLPYSHSPRMTKRTMGETFVKANTGDMHILDKNVPKEEATLDSES
What is the function of this protein?
Exhibits antimicrobial activity against Gram-negative bacterias, inducing bacterial membrane blebbing (By similarity).  Exhibits potent and dose-dependent vasoconstrictor and anti-edema activity in the cutaneous microvasculature, a physiologic effects which does not appear to be mediated via GALR1 or GALR2.
What are the official names of this protein?
Galanin-like peptide.
What is the protein family that this protein belongs to?
Belongs to the galanin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y988_MYCBO
Sequence: MLQRELTRLQNGWLSRDGVWHTDTDKLADLRALRDTLAAHPGTSLILLDTASDPRKVLAAVGVGDVDNAERVGVTMGGLNTRVSSSVGDMVKEAGIQRAKAAELRERAGWPNYDAVASIAWLGYDAPDGLKDVMHDWSARDAAGPLNRFDKGLAATTNVSDQHITAFGHSYGSLVTSLALQQGAPVSDVVLYGSPGTELTHASQLGVEPGHAFYMIGVNDHVANTIPEFGAFGSAPQDVPGMTQLSVNTGLAPGPLLGDGQLHERA
What are the official names of this protein?
Uncharacterized protein Mb0988c.
Protein: TGB3_CYMV
Sequence: MHLAIVGALTLVLTLFVLHYTTKDDRCYILINGHSAFTNCPASPDLAKVISQLKPHNHG
What is the function of this protein?
Plays a role in viral cell-to-cell propagation, by facilitating genome transport to neighboring plant cells through plasmosdesmata.  May induce the formation of granular vesicles derived from the Endoplasmic reticulum, which align on actin filaments (By similarity).
What are the official names of this protein?
Movement protein TGBp3, 7 kDa protein, Triple gene block 3 protein, TGBp3.
What is the protein family that this protein belongs to?
Belongs to the Tymovirales TGBp3 protein family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane.
Protein: RR4_PLETE
Sequence: MSRYRGARLRIVRQFDLKQTLRGLTRKRTDNRCMPGQHRKKRNDSTKKTKNSKKVAQYQIRLQEKQKLRFNYGITESQLINYVRQARKTKGSTGETLLQLLEMRLDNIVFRLGMAPTIPAARQLVNHGHIVVNNKKVDISSYQCQSQDVISVTKNKTIRTLISNFINSKTPKNLLRNPQIPSHLIFNKSTLLGTIKSVVPRRWIGLKIKELLIVEFYSRKA
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TYSY_ALBFT
Sequence: MSSHPIRSQYEDFLRHVSTHGVFKADRTGTGTTSVFGYQMRFDLNEGFPLVTTKKVFLKAIVLELLWFLRGDSNVKWLQERGCTIWDEWARPDGDLGPVYGVQWRSWPTPDGGHIDQIAEAIKTLKTNPDSRRIIVSAWNVAELDKMALMPCHAFFQFYVAPAQTPGGKGKLSCQLYQRSADIFLGVPFNIASYALLTHMVAQQCDLDVGDFIWTGGDCHVYSNHAEQVALQLSRTPFAYPTLSIKRKPASIFDYAYEDFEVLGYECHPAIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRHO_RHILO
Sequence: MTPSAPSQPVRVAALYRFARLDAFEALRAPLAAFCCGRGIKGTLLLAHEGINGTVAGSEEAIAELIDHIEAIDGLAGLEVKFSSATDMPFHRMKVRLKREIVTMGVEDIDPATSAGTYVAPADWNALISEPGTIVIDTRNTYEVSIGTFKGAVDPATASFREFPAWVEAHRAELEGRKVAMFCTGGIRCEKATAYVKSLGFEDVFHLKGGILKYLEEVPAEQSLWQGECFVFDERVSVSHGLAEGDAELCRACRHPLTASELTSPRYAAGVSCPHCFDARTDEDRQRYAERQRQVELAQARGKRPHIGS
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: IGSF2_HUMAN
Sequence: MAGISYVASFFLLLTKLSIGQREVTVQKGPLFRAEGYPVSIGCNVTGHQGPSEQHFQWSVYLPTNPTQEVQIISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPDTLSATMSSQTLGKEEGEPLALTCEASKATAQHTHLSVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRLSIERLQSSDQGQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNITADSLFAEGKPLELVCLVVSSGRDPQLQGIWFFNGTEIAHIDAGGVLGLKNDYKERASQGELQVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSHVHLRKPAARSVVMSTKNKQQVVWEGETLAFLCKAGGAESPLSVSWWHIPRDQTQPEFVAGMGQDGIVQLGASYGVPSYHGNTRLEKMDWATFQLEITFTAITDSGTYECRVSEKSRNQARDLSWTQKISVTVKSLESSLQVSLMSRQPQVMLTNTFDLSCVVRAGYSDLKVPLTVTWQFQPASSHIFHQLIRITHNGTIEWGNFLSRFQKKTKVSQSLFRSQLLVHDATEEETGVYQCEVEVYDRNSLYNNRPPRASAISHPLRIAVTLPESKLKVNSRSQVQELSINSNTDIECSILSRSNGNLQLAIIWYFSPVSTNASWLKILEMDQTNVIKTGDEFHTPQRKQKFHTEKVSQDLFQLHILNVEDSDRGKYHCAVEEWLLSTNGTWHKLGEKKSGLTELKLKPTGSKVRVSKVYWTENVTEHREVAIRCSLESVGSSATLYSVMWYWNRENSGSKLLVHLQHDGLLEYGEEGLRRHLHCYRSSSTDFVLKLHQVEMEDAGMYWCRVAEWQLHGHPSKWINQASDESQRMVLTVLPSEPTLPSRICSSAPLLYFLFICPFVLLLLLLISLLCLYWKARKLSTLRSNTRKEKALWVDLKEAGGVTTNRREDEEEDEGN
What is the function of this protein?
Plays a role as inhibitor of T-cells proliferation induced by CD3.  Inhibits expression of IL2RA on activated T-cells and secretion of IL2.  Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation.  Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium.  Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus.  Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells.  May be a marker of CD4(+) CD56(+) leukemic tumor cells.
What are the official names of this protein?
Immunoglobulin superfamily member 2, IgSF2, Cell surface glycoprotein V7, Glu-Trp-Ile EWI motif-containing protein 101, EWI-101.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SYC_SALPK
Sequence: MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHQDFDALNILRPDSEPRATHHIQEIIELTRTLIEKGHAYVADNGDVMFDVPTDPTYGQLSRQDLEQLQAGARVDVVDVKRNPMDFVLWKMSKEGEPSWPSPWGEGRPGWHIECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQSTCAHDGEYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARASLERLYTALRGTDKSAAPAGGEAFEARFVEAMNDDFNTPEAYSVLFDMAREVNRLKGEDMTAANAMASHLRKISGVLGLLEQEPDVFLQSGAQADDGEVAEIEALIQQRLDARKAKDWAAADAARDRLTEMGIILEDGPQGTTWRRK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT2_YEAST
Sequence: MSISESYAKEIKTAFRQFTDFPIEGEQFEDFLPIIGNPTLFQKLVHTFKTHLEEKFGKEKIDFIAGIEARGLLFGPSLALALGVGFVPIRRVGKLPGECASITFTKLDHEEIFEMQVEAIPFDSNVVVVDDVLATGGTAYAAGDLIRQVGAHILEYDFVLVLDSLHGEEKLSAPIFSILHS
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.  May lack catalytic activity.
What are the official names of this protein?
Adenine phosphoribosyltransferase 2, APRT 2.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FWDB_METJA
Sequence: MVKVVRNVVCPFCGTLCDDLEILVEDNHIVGTRHACRIGNAKFMHFEGAVRYTEPLMRENKKDDFKKVDYETAIEETARLLTEATLPLIYGWSATECHAHMYGVELAELVGAVIDNTASVUHGPSLLAVQDVGYPVCTLGEVKNRADVIIFWGSNPMHAHPRHMSRYSVFARGFFRERGREDRTLIVVDPRETDTAKLADIHLQVEPHKDYELVSAMRAVLKGFELQVDKVAGVPADLIYEAVEVCKNAQFGELFFAMGVTMTRGKHRNIDNAIQLVIDLNAYTKFGLMPMRGHYNVNGFNQVLTWVTGYPFGVDFSRGYPRYNPGETTANDLLQRGETDMMLNIASDPGAHFPQKAVQHMAKIPLVCIDPHETPTTQLANIIIPPAIAGVEVEGTAYRMDGVPIQLRKVIDPPEGVLPDREILKILIKKVKEML
What is the function of this protein?
Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR).  This enzyme is oxygen-labile.
What are the official names of this protein?
Tungsten-containing formylmethanofuran dehydrogenase 2 subunit B, Tungsten-containing formylmethanofuran dehydrogenase II subunit B.
What is the protein family that this protein belongs to?
Belongs to the FwdB family.
Protein: NOP10_DESA1
Sequence: MNWLLRKCSKCGRYTLSRDRCPYCGGELIVPHPPRFSPIDKYVEYRLEEKLSKGIIKLDEKPPYKP
What is the function of this protein?
Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
What are the official names of this protein?
Ribosome biogenesis protein Nop10.
What is the protein family that this protein belongs to?
Belongs to the NOP10 family.
Protein: PG078_VACCP
Sequence: MDKLYAAIFGVFMGSPEDDLTDFIEIVKSVLSDEKTVTSTNNTGCWGWYWLIIIFFIVLILLLLIYLYLKVVW
What is the function of this protein?
Late protein which probably plays a role in virus entry into the host cell.
What are the official names of this protein?
Protein OPG078, Protein I2.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG078 family.
Protein: HSFX4_HUMAN
Sequence: MASQNTEQEYEAKLAPSVGGEPTSGGPSGSSPDPNPDSSEVLDRHEDQAMSQDPGSQDNSPPEDRNQRVVNVEDNHNLFRLSFPRKLWTIVEEDTFKSVSWNDDGDAVIIDKDLFQREVLQRKGAERIFKTDNLTSFIRQLNLYGFCKTRPSNSPGNKKMMIYCNSNFQRDKPRLLENIQRKDALRNTAQQATRVPTPKRKNLVATRRSLRIYHINARKEAIKMCQQGAPSVQGPSGTQSFRRSGMWSKKSATRHPLGNGPPQEPNGPSWEGTSGNVTFTSSATTWMEGTGILSSLVYSDNGSVMSLYNICYYALLASLSVMSPNEPSDDEEE
What are the official names of this protein?
Heat shock transcription factor, X-linked member 4.
What is the protein family that this protein belongs to?
Belongs to the HSF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BARS1_ARATH
Sequence: MWRLRIGAKAKDNTHLFTTNNYVGRQIWEFDANAGSPEELAEVEEARRNFSNNRSRFKASADLLWRMQFLREKKFEQKIPRVIVEDAEKITYEDAKTALRRGLLYFTALQADDGHWPAENAGSIFFNAPFVICLYITGHLEKIFTHEHRVELLRYMYNHQNEDGGWGLHVESPSNMFCSVINYICLRILGVEAGHDDKGSACARARKWILDHGGATYSPLIGKAWLSVLGVYDWSGCKPIPPEFWFLPSFFPVNGGTLWIYLRDIFMGLSYLYGKNFVATSTPLILQLREEIYPEPYTNISWRQARNRCAKEDLYYPQSFLQDLFWKGVHVFSENILNRWPFNNLIRQRALRTTMELVHYHDEATRYITGGSVPKVIAVFHMLACWVEDPESDYFKKHLARVPDFIWIGEDGLKIQSFGSQVWDTALSLHVFIDGFDDDVDEEIRSTLLKGYDYLEKSQVTENPPGDYMKMFRHMAKGGWTFSDQDQGWPVSDCTAESLECCLFFESMSSEFIGKKMDVEKLYDAVDFLLYLQSDNGGITAWQPADGKLVEFIEDAVVEHEYVECTGSAIVALAQFNKQFPGYKKEEVERFITKGVKYIEDLQMVDGSWYGNWGVCFIYGTFFAVRGLVAAGKCYNNCEAIRRAVRFILDTQNTEGGWGESYLSCPRKKYIPLIGNKTNVVNTGQALMVLIMGNQMKRDPLPVHRAAKVLINSQMDNGDFPQQEIMGVFKMNVMLHFPTYRNMFTLWALTHYTKALRGL
What is the function of this protein?
Converts oxidosqualene to baruol (90%) and 22 minor products.
What are the official names of this protein?
Baruol synthase, AtBARS1, Pentacyclic triterpene synthase 2, AtPEN2.
What is the protein family that this protein belongs to?
Belongs to the terpene cyclase/mutase family.
Protein: FOXG1_CHICK
Sequence: MLDMGDRKEVKMLPKSSFSINSLVPEAVQSDNHSGHSHHNSHHPHHHHHHHHHHPPPPQQPQRAAAAEEEDEEKAPLLLPPPAAGALEAAKAEALAGKGEAGAAAAELEEKEKAAEEKKGAAEGGKDGESGKEGEKKNGKYEKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYRENKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSSDDVFIGGTTGKLRRRSTTSRAKLAFKRGARLTSTGLTFMDRAGSLYWPMSPFLSLHHPRASSTLSYNGTASAYPSHPMPYSSVLTQNSLGNNHSFSTSNGLSVDRLVNGEIPYATHHLTAAALAASVPCGLSVPCSGTYSLNPCSVNLLAGQTSYFFPHVPHPSMTSQSSTSMTARAASSSTSPQAPSTLPCESLRPSLPSFTTGLSGGLSDYFTHQNQGSSSNPLIH
What is the function of this protein?
May determine the nasotemporal axis of the retina, and consequently specify the topographical projection of the retinal ganglion-cell axons to the tectum by controlling expression of their target genes.
What are the official names of this protein?
Forkhead box protein G1, FoxG1, Brain factor 1, BF-1, BF1, cBF-1, CEQ 3-1, Forkhead-related protein FKHL1, N-62-5, Proto-oncogene C-QIN.
What are the subcellular locations of this protein?
Nucleus.
Protein: SOX18_XENTR
Sequence: MHRPEPSYCREEPTPCQGVNSTWVPPADTVPETSPTPSSPPAPDSPTPSPQPGYGYSPCEEKPGDPRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGQSWKNLSSAEKRPFVEEAERLRVQHLQDHPNYKYRPRRKKQAKKLKRVDPSPLLRNEGYRGQAMANLSHFRDLHPLGGSGDLESYGLPTPEMSPLDVVEPSEPAFFPPHMREEADPGPFRTYQHGVDFGQEKTLREISLPYSSSPSHMGGFLRTPTASAFYYNPHGGSPACTPLGQLSPPPEAPALEAMDHLGPAELWGDFDRNEFDQYLNMSRTQGPGYPFPMSKLGAPRTIPCEESSLISALSDASTAMYYTPCITG
What is the function of this protein?
Transcription factor.  Binds to the consensus DNA sequence 5'-AACAAT-3'.  Also binds 5'-CACAAT-3' and 5'-AATAAT-3' but with a lower affinity.  Acts partially redundantly with sox7 during cardiogenesis, acting indirectly through nodal-signaling to induce mesodermal, organizer and endodermal tissues, which then interact to initiate cardiogenesis.  Also acts as an antagonist of beta-catenin signaling (By similarity).
What are the official names of this protein?
Transcription factor Sox-18, SRY (sex determining region Y)-box 18.
What are the subcellular locations of this protein?
Nucleus.
Protein: DPOLA_SCHPO
Sequence: MRKRNAGIKPSQRFAELRALRQAGKTRASTYESKENEELYDNVSEEEYRKIVRQRLDEDDFVVDDNGAGYVDNGYDEWDQSHYSDEDDENEKGSSGRKRKKSKNVLAEPNQQIGAFFKANAIQPASRIANRKNNEKEDEFMAEILGSIDQDIPERLSTKKGNRSHTTSNAKRRSQKAASSISTTNVVSSDPKKYIPETVPSTPQPASSLPIPSSPPAALETEENVDSQPMELDEPELPVGSDAPIIDVEESIAMKPLMSHDQVDDTASLSKATISQQPLSPMTPLSSELDVSAFSEINSKIKNVDVPASSYSSPISKVSPSDVTEEDGSLFFFWMDYTEMYGSLCLFGKVYDKATKQYVSCFLKVDGIMRSLYFLPRPSSSSVSEDSIAAQTKDVYDEVANLLSKRGVKEWKSRVSKYKYAFELEDVPRTADYLEVIYSYSYPALPTDLTGSSFSHVFGTNTALFEQFVLSRRVMGPCWLKIQQPNFDAVKNASWCRVEIGCSSPQNISVSFEKNEITSKTPPMTVMSLAFRTLINKEQNKQEVVMISARIFENVDIEKGLPANDMPSYSFSLIRPLKQIFPNGFEKLARQHKSSIFCERSEVSLLNNFLNKVRTYDPDVYFGHDFEMCYSVLLSRLKERKIHNWSSIGRLRRSEWPRSFNRSSQQFVEKQIIAGRLMCDLSNDFGRSMIKAQSWSLSEIVLKELDIKRQDINQEKALQSWTDTAHGLLDYLVHCEIDTFFIAAVAFKIQMLQLSKNLTNIAGNSWARTLTGTRAERNEYILLHEFKKNGYIVPDKQQSIRRHAEAFGAEDGLQEESLGKKKDKYKGGLVFEPQKGLYETCILVMDFNSLYPSIIQEYNICFTTVDRSPSNSDSDDQIPDTPSASANQGIFPRLIANLVERRRQIKGLLKDNSATPTQRLQWDIQQQALKLTANSMYGCLGYTKSRFYARPLAVLITYKGREALMNTKELADQMGLQVIYGDTDSVMLNTNVTDKNHALRIGNEFKEKVNERYSKLEIDIDNVYQRMLLHAKKKYAALQLDSQGKPNLDVKGLDMKRREFCTLAKEASKFCLDQILSGELTETVIENIHSYLMDFSEKMRNGKFPANKFIIFNRLGKNPEDYPNGKTMPFVQVALKKKARGENVRVGDVIPFIIAGSDADGHPADRAYSPQEIMNTNSTLVIDYNYYLSHQILPPIERVIAPIEGTNRARLAECLGLDARKYYSHETSESSAFQRYESTLTDDQCFINVSPLLLKCPSCNATSFSLRSVKSLKETLYANTVECDCGYEYSDFTIILQFSSQLRDFINLYYEGILVCDDSSCGNRTRQMSVYGKRCCNKSCRGSVHFEYNDEQLYNQIKFLLKAVQTTTGATRNGIIRCNAINKNISRIMNKNAREFVDMGLIFSS
What is the function of this protein?
Catalytic subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis (PubMed:15314153, PubMed:15643072).  During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit pol1, an accessory subunit spb70/pol12 and two primase subunits, the catalytic subunit spp1/pri1 and the regulatory subunit spp2/pri2) is recruited to DNA at the replicative forks.  The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands (By similarity).
What are the official names of this protein?
DNA polymerase alpha catalytic subunit, DNA polymerase I.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PUR5_DESPS
Sequence: MSTTSEAVQSKYSEAGVDIDKGNAFVEGIKDIVASTHKNGVIDNIGGFSAHIAIDVTKYPKPVIVNSTDGVGTKLAIAHMCNKHDTIGIDLVAMCVNDLIVGGATPLSFLDYFAVGKLDIEVATEVVKGIAEGCKQAGCSLVGGETAEMPGLYQGSDYDLAGFVTGIVDRDSIIDGSDVRSGNKIIGLASSGVHSNGYSLVRKICFDDNDYSVEDHIEELGSTLGEELLKPTRIYVQQVLNVIKNYPIHGMVHNTGGGFIDNIPRILPKGYKATLQAGSWDVPAIFTFLEEKGKVPREEMYRTFNMGVGLLVIVAEDKAEDILHHFEALGEKASIIGEIQKQTDENDERVTILPEG
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBS_METJA
Sequence: MGITMFKEFKALLSFFTRIPIYVEDFDFENIANYFYLIILIGYVFGIFSLILGYIFSFLLPNFLSAVLILFFIEYLNGFHHIDGLIDFGDGWMAVGDKRKKLMAMKDRYIGCGGVVFAIFFNLMAVISLSYILDINILYLLVGEVCAKLGMLSCSTFGNPLIEGTGRYFVKKADEKFLTIGIILSLPLLLIFSGIERKIVIIAIITTIITGLCMAKIAKRHFGGVNGDVLGASNEITRVVVLLSIIASIKVFSIYLLG
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL16_PELPB
Sequence: MLMPKRVKYRKTQRGRMKGNSGRGTDVSFGSFGLKAIEPAWITSRQIEAARVAMTRFMKRDGKIWIRIFPDKPVTKKPAETRMGSGKGSPEFWVAVVKPGRIMFEADGVPKEVATEAFRLAAKKLPIKTRFIVRPDYED
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.