PharMolix/UniProtQA huggingface dataset:
Protein: ATPI_TETOB
Sequence: MSDFLLNPFSEIAEVSVGQHFYWQLGSYEVHGQVLLVSWFVLAVIFGLSFVGNSNLKSTPDGLQNFTEFVTEFIRDLAKTQIGEEEYLKWVPYLGTVFLFIFVSNWSGALLPWALIELPNGELAAPTNDINTTVALALLTSISYFYAGIRKKGLRYFNRYVQPAAFLLPINVLEDFTKPLSLSFRLFGNILADELVVGVLVSLVPLIIPIPIMLLGCFTSAIQALVFATLAGAYIGEAVEDHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SIGI6_ACET2
Sequence: MDWHFQGTNDDREHTKRIIIEYLNRIKAGDDSAREEFILRFRPFILKLVYKATDRHVEPENSEEYSVALLAFNEAINAYDEEKHSNFLVFSEQVINRRLIDYKRKNHKNKMVYPFSYFENEDIKLERTLSDADGNNAIERLEFTDEIRLFKSELASFDITFKDLLSCTPKHRDSRELLINIAKKIASNDGLYEKLKKTKKLPTLELLKLAKVSRRTIERNKKYIIAVSLILRSNLEIFKEYAAGIQEKEVDLR
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity).  This sigma factor is involved in regulation of cellulosomal genes via an external polysaccharide-sensing mechanism (Probable).  Recognizes the predicted promoters associated with sigI6 itself, xyn11B, xyn10D, xyn10Z, xyn10Y, cel9V, cseP, sigI1, cipA, and rsgI5 (PubMed:26731480).
What are the official names of this protein?
RNA polymerase sigma factor SigI6.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. SigI subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_RHOPA
Sequence: MMSNNMPRHFLDLTELPTSELRNMLSAAVAMKAKRKANADGEKPLAGKTLAMIFDKPSTRTRVSFDVGMRQLGGESIMLTGAEMQLGRGETIADTARVLSRFVDIIMIRILNHEALLELAANATVPVINGLTRKSHPCQVMADVMTFEEHRGPIKGRTIAWTGDDNNVLASFAHAAQRFEFKLNIATPPQLSPSKALRDWIKASGAAITIGTDPEEAVRGADCVVTDTWVSMGDKDGEHRHNLLKPYQVNAKLMSLAHKDAIFMHCLPAHRGEEVTDEVIDGPQSVVFDEAENRLHAQKGILAWCLGAVA
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_PSEP1
Sequence: MSTTPATPKVGFVSLGCPKALVDSERILTQLRMEGYEVVPTYEDADVVVVNTCGFIDSAKAESLEVIGEAIKENGKVIVTGCMGVEEGSIRDVHPSVLSVTGPQQYEQVVNAVHEVVPPRQDHNPLIDLVPPQGVKLTPRHYAYLKISEGCNHSCSFCIIPSMRGKLVSRPVGEVLSEAERLVKAGVKEILVISQDTSAYGVDVKYKTDFWNGRPVKTRMLELCEALSSLGAWVRLHYVYPYPNVDDVIPLMAAGKILPYLDIPFQHASPKVLKSMKRPAFEDRTLARIKNWREQCPELVIRSTFIVGFPGETEEDFQYLLDWLTEAQLDRVGCFQYSPVEGAPANDLGLAEVPDDVKQERWDRFMAHQQAISAARLQLRIGKEIDVLIDEVEEQGSVGRSFFDAPEIDGSVFIDGDHGFKPGDKVRCRVVDADEYDMWAEPI
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_SHESW
Sequence: MLPKVLFLMGPTASGKTALALELAENHNCEIISVDSALIYRGMDIGSAKPSIEELARGPHRLIDIRDPSESYSAADFRADALAEIEQIIRMGKTPLLVGGTMMYFKALLEGLSPLPSADDAIRADIQAEADAKGWETLHDQLRDIDPVSAERIHPNDPQRLSRALEVYRISGKSLTELTQTKSAPLPYDVVQFAIAPRERKVLHDLIAQRFRIMLQQGFIGEVTQLKARGDLHLDLPSMRCVGYRQCWQHLDGEFDYDTMVEKAVAATRQLAKRQLTWLRSWPELNWLESGAEGNLVTLMRHCR
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: CLPP_YERP3
Sequence: MSYSGERDQFAPNMALVPMVVEQTSRGERSYDIFSRLLKERIIFLTGQVEDHMANLITAQMLFLEAENPEKDIFLYINSPGGVITAGMSIYDTMQFIKPDVSTICMGQACSMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGFQGQATDIEIHAKEILKVKSRMNELMAYHTGKSLEEIERDTERDRFLSAEQSVEYGLVDSVFTRRD
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_MYCS5
Sequence: MSNTFSKNNVKKIKQISLSLATNEDVLSWSNGVVSKPETINYKTYKPEKDGLFDEIIFGPVTDFKCPICFTKYKKSDENTICKRTTSCEKIQPKILPKISRRSRMGHIALNNPVVHFWFFKINHSTISKLLGLKVAGSNKPVTKSDLEKIIYYKSHIVLETGGLKSLQKNTIIDINDAADIYAGALEEILEFNKDNKDGYEEILDTLNDLKEYAASKTGQDYGIDFYEYNEIIEEYSQAKIGTGSKAIEYLLKNIDLEKESKEIQDEIDTINDQNKYEISSSEALKRNKLYKRLAIIKSFLKSGQKPENLLIYNLPVIPADLRPLVQLDGGRHSTSDINELYRRIIIRNNRLEKWYESDAPVLIKQNEFRMLQEAVDALIDNSRKKPGPVTSKDGHPFKSISDALVGKKGRFRQNLLGKRVDYSGRSVIVVGPHLKMYQVGIPRDMAAKLFEPWIINRIMKEEEGINSVKAAKKLVDSLNPIIWPYVEQVLENRPVLLNRAPTLHRLSIQAFQPVLIRGKAIKIHPLVTTAFNADFDGDQMAVHVPISKAAVREAQELMLASKNILGPKDGEPIINPSQDIILGLYYLTIEKANQKNEGKFYPSFNEMMLAYENKYINLATRVVLPVSALKKISILQKTDAPYIYSTVGKFILNNAFPRDFDFVFGKRVTEKLTSTNEHGEEVVSLKTKIDTSEHDIKRYVFNYGDNFTAKIKEADVNLPLNKKEIAKIVRNIYEKYVPIVNIEDISQVINKIDKTQLDNLHELCSELKDFNGNKLEDNRIHLELLVRLIKEEFLKIQDQYFAKDEESIFNHKYWELKHYTKLLERVWFRYSNYVSTVLDVIKDLGFKFSTKSGITISMNDIVTSKTTKERIKKAEEETEALKDYFKKGYLTDDERYTLTIKKWSDVKESIEKELKKVVDSNLDNPLFMMLSSGARGTYSNFTQLAGMRGLMNNNTKILKADAENDRVVRSIVEIPVKSSFLDGLTAYEFYSSTHGARKGLTDTALNTAKSGYLTRRLVEVAQGVVIREEDCGSDYGFVVKDIKDTKTNTIIESLQERIEGRFTAVPIYDQNGKLIVKESELITPEIASEIVAKGITKVEIRSVLSCHTRNGLCKKCYGKDLATNRIVNIGEAVGVIAAQSIGEPGTQLTMRTFHTGGVAGGEDITGGFGRLIELIDAYDQPWGTPAEISRHYGKVKKIETQKNKKGKESGQFNISVEYFDEDGNKQTHQYLVKSSQRLRVKQGDEVVAGQKLSEGPIVLNELLESVDTRAVQNYILKEVQKLYRLQGIAIADKYIEIIIRQMLSKISIIDPGDSSFYSGSLVDAFVYQKENGILLSQGKKPAYGVVKIKGAKQTPLLSDSWLAAASYQETAKILVDASIAKRTDNLEGLKENIIIGYKIPAGTNSNFEENGKYNLKEFSSYFPNKYDSTPELKLEEITDENIEEEFDYLKENTISEEEFENLDDDTMYHLETSDEFEDESFGEDDFEYSEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: TAUB_SHIF8
Sequence: MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSIQLAGKRIEGPGAERGVVFQNEGLLPWRNVQDNVAFGLQLAGIEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSDGQRQRVGIARALAANPQLLLLDEPFGAQDAFTRDQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSSGPGRVLERLRLNFARRFVAGESSRSIKSDPQFIAMREYVLSRVFEQREAFS
What is the function of this protein?
Part of the ABC transporter complex TauABC involved in taurine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Taurine import ATP-binding protein TauB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: AMPA_SACD2
Sequence: MEFIAKKADIATLSTQCVVVFCKDGKLMASASHLDTEQHGLLTHQLSIKAISPTAGSHLWLTLAPTKSAKHSKALLVQLGESKKKSADITIEDIRKISQKLASTLNSAKLKDAAVFFDSALPASGDCTLEKLAHTLALEIERASYRFSLKAGTKNTPATLKKVVFVATNSAETKTLRNGANTGSAMGKGINAARELGNLPGNICTPNYLAEQAKQLAAGCKKLTSKALGEKQMERLGMGAFLSVSKGSDQEGKLILLEYKGAAANKAPHVLVGKGVTFDTGGISLKPGANMDEMKFDMCGAASVLGTFKALVELDAKVNVVGIIAAAENMPSGGASKPGDVVTSMSGQTIEILNTDAEGRLVLCDALTYAERYKPKSVVDIATLTGACVVALGNHAAGLYSNTQSVADALLKAGEETHDRAWQMPLWDDYQRQLDSNFADMGNIGGMPGGSITAACFLSRYTKKYPWAHLDIAGVAWHSGAKKGATGRPVSLLVNYLLNN
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRA_AZOC5
Sequence: MFWSKKPLDLPTPETALKGRPDAIPTARLHHVNQNPLKGPYPDGFRTAIFALGCFWGAERAFWRTPGVWVTAVGYLAGLTPNPTYEEVCSGRTGHTEGVLVVYDPAVISYADLVKLFFESHDPTQGMRQGNDVGTQYRSGIYTSDPQEKAVAEAVKASYEAALKAKGFGPITTEIIDGGPFYFAEDYHQQYLSKNPGGYCGLGGTGVSCPIGVGVAAQ
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: GREA_BRUA2
Sequence: MEKFPMTPRGFEKLKEELRWRQQSERPRIIEAIAEARAHGDLSENAEYHAAKEAQSLNEGRINELEDLVARAEVIDVSKLTGDRIKFGATVTMIDEDTEEEKIYQIVGDQEADVKEGRISISSPIARALIGKGEGDTIEVNAPGGSRSYEIIALKFV
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: STAU2_XENTR
Sequence: MTNPKEKTPMCLVNELARFNRIQPQYKLLDERGPAHSKLFTVQLTLGEQTWQAESTSIKKAQHAAASLALSETTLPKPAARQTKNHMNNNPEAAELHGNTFTSSRHSAKGSITPTVELNGLAMRRGEPAIYRSLDPKPLPNQRANYNYRGMYHQRYLCPMLKTFYVQLTVGNSEFYGEGKTRQAARHNAALKALHALRNEPIPERSSLNGEANRGPEEDKDANKSEISLVFEISLKRNLSLSFEVIKESGPPHMKSFVTRVTVGEFTAEGEGNSKKLAKRRAAAAVLQELRKLPPLPVIEKPRIYIKRRPKNIIKASPEYGQGMNPISRLAQIQQAKKEKEPEYVLLSERGIQRRREFVMQVKVGEETATGTGPNKKTAKRNAAEAMLLQLGYKASSPVVEKTGKRGENPDWDEQNSGIADQTSTPKGILHLSPDVYQEMEASRNKTVPAPAISYLSSKEMNQASSSFFSTSVSQSCTAAIARELLTNGTSPTAEAIGFTGKNLMCHSSTVQPSKQLEYLAGIQGLQVNYSDRQSGNDFLTCLTLSPVQMTFHGIGSSLEASHDQAALSALKQFSEQGLDSVDGSLMAENGPFEQAKLRGEKADNKQANSGTIAQDCKDSKAVV
What is the function of this protein?
RNA-binding protein required for the microtubule-dependent transport of RNAs within polarized cell types.
What are the official names of this protein?
Double-stranded RNA-binding protein Staufen homolog 2.
Protein: HSLU_VIBVY
Sequence: MSEMTPREIVHELNRHIIGQDNAKRSVAIALRNRWRRMQLEESLRVEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVESIIRDLTDVAVKLTHQQAMEKVKFRAEELAEERILDALLPPPRDAWGQNEQSEDTSNTRQIFRKKLREGKLDDKEIEINVAAPQMGVEIMAPPGMEEMTNQLQGMFQSLAGNTSKKRKLKIKDAFKALIEEEAAKLVNQDELKEQAIYSVENNGIVFIDEIDKICKRGESSGPDVSREGVQRDLLPLIEGSTVSTKHGMVKTDHILFIASGAFQVAKPSDLIPELQGRLPIRVELEALSSHDFKRILTEPRASLTEQYVALMKTEDVDIEFTEDGITQIAEAAWTVNETTENIGARRLHTVMERLMDEISFDATEKSGTKFVIDAAYVQQRLGEFVEDEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1050_STACT
Sequence: MNQHFHRGILFYHQAAGQGNLYKSLGQVTESLTQMCDDLTLKLSEEGGDIAKFCDDLTQNQNGVSYDVFFVLGGDGTVNELVNGVARNNLEIPIGIIPGGTFNDFTKTLNLSPRTAAAANELLNSKIKSFDVLKVNDTYALNFAGIGMMVQNSENVDANKKRILGKFSYVFTTLKVIANPKIYQYTIKANNEEYSGETSMILIANGNYVGGSKIPLEDLSPSDGEMNIFVFKNHNMSLIKDFFQVKDSLRWNDITENIRLITTDEMKLETRPSTKIDIDGEIMFDTPVDIKLLKDKVKLLYIDVNE
What is the function of this protein?
May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG).
What are the official names of this protein?
Putative lipid kinase Sca_1050.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family.
Protein: RECA_PSYA2
Sequence: MDDNKAKALKAALAQIEKQFGKNTIMHLGDDSAALDVDVVSTGSLGLDIALGIGGLPKGRIVEIYGPESSGKTTMTLQAIAECQKQGGVCAFIDAEHALDPVYARKLGVNTDDLLLSQPDNGEQALEITDMLVRSGAIDMIVIDSVAALTPRAEIEGEMGDSHMGLQARLMSQALRKITGNAKRSNCMVLFINQIRMKIGVMFGSPETTTGGNALKFYASVRMDIRRIGAVKNGDEIIGNQTRVKVIKNKMAPPFRQAEFEITYGEGTNHLAEVIDLGVEIGAVGKAGSWYSYGDEKIGQGKANSVLFLKENPAIAEEIEAKIRAEKLGVKDDSKAAVVAETNEELASEPVQ
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_HELP2
Sequence: MVVAKKSLGQHFLTDESFLDRIVNALPPLNPLKLIEIGVGLGDLTLKLLDRYPLKTYEIDSNLCEKMRSKLKAQKKPFKLELVEKDALFLKEEEPYFLISNLPYYIATRLVLNALKDPKCRGLLVMTQKEVALKFCTKDSQNALSVLVHTIGNATLLFDVPPSAFSPPPKVFSSVFEVIKEPLKEKALASLTQVPFFEEALQKGFETLEDFLKACFSSPRKTLSNNLKKSVSYREKLDKVLDFLALESQPTSVRASEVKDYLKLLEYLLKG
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRKF_CYPDO
Sequence: SIVLRGKAPFR
What is the function of this protein?
Inhibits angiotensin-converting enzyme (ACE) with a Ki of 1. 2 uM, targets B1 bradykinin receptors (BDKRB1), and potentiates the smooth muscle contraction elicited by bradykinin.  In vivo, induces hyperalgesic effects in living rats after intraplantar injection.
What are the official names of this protein?
Fulvonin, Bradykinin-related peptide.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-related peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: RASA1_BOVIN
Sequence: MMAAEAGGEEGGPVTAGAAGGGAAAASGAYPAVCRVKIPAALPVAAAAPFPGLAEAGVAATLGGGAALGSGFLGAGSVAGTPGGVGLSAGGAAAGVAGVAAAAAGAGGEMAFAKGTTSLPTETFGAGGGFPPLPPPPPQLPTLGAGLGTVDEGDSLDGPEYEEEEVAIPLTAPPTNQWYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQTNVVNHFRIIAMCGDYYIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVAPPEPVEDRRRVRAILPYTKVPDTDEISFLKGDMFIVHNELEDGWMWVTNLRTDEQGLIVEDLVEEVGREEDPHEGKIWFHGKISKQEAYNLLMTVGQACSFLVRPSDNTPGDYSLYFRTSENIQRFKICPTPNNQFMMGGRYYNSIGDIIDHYRKEQIVEGYYLKEPVPMQDQEQVLNDAVDGKEIYNTIRRKTKDAFYKNIVKKGYLLKKGKGKRWKNLYFILEGSDAQLIYFESEKRATKPKGLIDLSVCSVYVVHDSLFGRPNCFQIVVQHFSEEHYIFYFAGETPEQAEDWMKGLQAFCNLRKSSPGTSNKRLRQVSSLILHIEEAHKLPVKHFTNPYCNIYLNSVQVAKTHAREGQNPVWSEEFVFDDLPPDINRFEITLSNKTKKSKDPDILFMRCQLSRLQKGHATDEWFLLSSHIPLKGIEPGSLRVRARYSMEKIMPEEEYSEFKELILQKELHVVYALSHVCGQDRTLLASILLKIFLHEKLESLLLCTLNDREISMEDEATTLFRATTLASTLMEQSMKATATQFVHHALKDSILRIMESKQSCELSPSKLEKNEDVNTNLAHLLNILSELVEKIFMASEILPPTLRYIYGCLQKSVQHKWPTNTTMRTRVVSGFVFLRLICPAILNPRMFNIISDSPSPIAARTLTLVAKSVQNLANLVEFGAKEPYMEGVNPFIKSNKHRMIMFLDELGNVPELPDTTEHSRTDLCRDLAALHEICVAHSDELRTLSNERGAQQHVLKKLLAITELLQQKQNQYTKTNDVR
What is the function of this protein?
Inhibitory regulator of the Ras-cyclic AMP pathway.  Stimulates the GTPase of normal but not oncogenic Ras p21.
What are the official names of this protein?
Ras GTPase-activating protein 1, GAP, GTPase-activating protein, RasGAP, Ras p21 protein activator, p120GAP.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRRA_MYCTU
Sequence: MDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ
What is the function of this protein?
Member of the two-component regulatory system PrrB/PrrA that is involved specifically in early intracellular multiplication of Mycobacterium and is essential for its viability (PubMed:11953357, PubMed:22081401).  Upon phosphorylation by PrrB, functions as a transcription regulator by direct binding to promoter regions of target genes to positively regulate their expression.  Autoregulates its own expression (PubMed:14702417, PubMed:29101285).
What are the official names of this protein?
Transcriptional regulatory protein PrrA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRS2C_ORYSI
Sequence: MDHDPKERLLLPPRAAAAAAANGPHRRAAPAAGGGGGGVAIDVHGLKRRGGGRRSWVRVDAATGASEAVEVAKPALMRRLDLPARDLRLLDPLFVYPSAILGRERAVVCNLERIRCIITADEALILRDPDVAGGGAETEEAVRRYVAELQRRLVDRADDLPFEFIALEVALEAACSFLDAQAVELEADAYPLLDELTTKISTLNLERVRRLKSKLVALTRRVQKVRDEIEQLMDDDGDMAEMYLTEKKRRMEASLLEEQAFQGMGNSGFGSSFSAPVSPVSSPPASRRLEKELSFARSRHDSFKSADSSQYSIEELEMLLEAYFVVIDYTLSKLTSLKEYIDDTEDFINIQLDNVRNQLIQFELLLTTATFVVAIFGVVSGVFGMNFEVDLFNVPHAFEWTLVITGVCGLVIFCCFIWYFKKRRFFPL
What is the function of this protein?
Magnesium transporter that may mediate the influx of magnesium.
What are the official names of this protein?
Magnesium transporter MRS2-C.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35.5) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y1318_METJA
Sequence: MKTWRENMKKILTLLLITFLLNSAFAVIIKAPAVSLTDRGYVGVPINIQINVTKGDGHVFMDTMPLTELDMQGSARIAAKVAGEVTGKDMSKYNVYITVRSDVPVVGGPSAGGTMTIGIICELMNWSLNKHVMMTGTINPDGSIGPVGGILEKIEAAKKANCTIMLIPKGQRYVEVEGNKVDAVEFGKKLGIKVIEVGSIYEAIPYFTNKKIIMKEYPENPLIEEKYKDIMKELSENVLKTANEKYENLSKELSNSYVGYEYQKALLNELTTSKSLLEKANDEYLKNKYYSATCSAFNALIKLETIEHTLKYLTGEEDVKTFLTEVQNKISHDKEIVYSKNVTTNNFEEILAGRIRIAEAEKLLDNAWKSYYLGNYDEAIKYGSFAKLRGDSAIWWVSLKENDNNGKIINEAKLKSLAQQYLDNAETILTYVETLFPNLPTDDLENDLESAKEAYKDGDYLLTIAESIDTCVKAEIPLVIFGDIEYSKKYARNKINLAENLGITPISALGYYEYANSLNDTISKIMYYKYSSYYAQMDIDVIKELNKSISENISSEINIVTNENVNIEETTTKENNVGIMISAIIGGLIGFAGGYLARRVSA
What are the official names of this protein?
Uncharacterized protein MJ1318.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS6_METPB
Sequence: MLKTRIIPCLDVKDGRVVKGVQFLELRDAGDPVESAKAYDAAGADELCFLDITASHEDRGTLLDVVSRTAEACFMPLTVGGGVRTVSDVRTLLLAGADKVGINTAAVKNPDFVAEAAEKFGDQCIVVAIDAKRVSGPHEAARWEIFTHGGRNPTGLDAVEFARKVSERGAGELLVTSMDKDGTRSGYDLALTRAIADAVKVPVIASGGVGGLDDLVAGVRDGGASAVLAASIFHFGQHTVAEAKSHMAAAGLAMRLDP
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GREA_STRSY
Sequence: MAEKTYPMTLEEKEKLEKELEELKLVRRPEIVERIKIARSYGDLSENSEYEAAKDEQAFVEGQISTIETKIRYAEIVNSDAVAADEVAIGKTVTVQEVGETEEEVYHIVGAAGADVFANKISNESPIGHALIGKKTGDVATIETPAGSYDVKILKVEKTK
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: PPNP_CLOD6
Sequence: MSEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEYTFSTREEEIMEMLAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSYIAD
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: ATPA_PELPB
Sequence: MSTTVRPDEVSSILRKQLAGFESEAEVYDVGTVLQVGDGIARVYGLSKVAAGELLEFPNNVMGMALNLEEDNVGAVLFGESNLVKEGDTVKRTSILASIPVGEAMLGRVINPLGEPIDGKGTIDTQIRLPLERRAPGVIYRKSVHEPLQTGLKAIDSMIPIGRGQRELIIGDRQTGKTAVAIDTIINQKGKGVFCIYVAIGLKGSTVAQVVNTLEKYDAMEYTTVISATASDPAPLQFIAPFAGATLGEYFRDTGRHALVVYDDLSKQAVAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAAKITDDIEVARKMNDLPDALKSLVKGGGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLESNLFNSGQRPAINVGISVSRVGGSAQIKAMKKVAGTLRLDLAQFRELEAFSKFGSDLDKTTKAQLDRGARLVEILKQGQYIPMPVEKQVAIIFLGTQGLLDTVDLRFIRKFEEEFLSLLEIKHNDLLAKIASSGALEADTAAKLKDIAVKFVTVFKEKNKA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SRR1L_SCHPO
Sequence: MDFIVVKRSRKKKNGRGKFPKVSNTITQGDTDLWSQDTLQRKLDNSREKLEYSEFLKSVQSQLSEFKDPIHKCIILGLGRIHTLTASLQLSLFFEIMKIFNLQPRFCSFYDPAFLKDDVEFLENKGFCVLPDPPTPSCLKYTLLYMPHCPTSLYETWLAAYVNDDPRHFIMCGNNLQLYVDNKPSKEIVSTYPNVYKMCTKNYYTRLLFPEFPNVYAFNDLSFHFHDAQSFVEKKQPSKFVDASSVAEHPS
What are the official names of this protein?
SRR1-like protein.
What is the protein family that this protein belongs to?
Belongs to the SRR1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.