PharMolix/UniProtQA huggingface dataset:
Protein: TOLA_ECOLI
Sequence: MSKATEQNDKLKRAIIISAVLHVILFAALIWSSFDENIEASAGGGGGSSIDAVMVDSGAVVEQYKRMQSQESSAKRSDEQRKMKEQQAAEELREKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAAKKAAADAKKKAEAEAAKAAAEAQKKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEKAKAEAEKKAAAEKAAADKKAAAEKAAADKKAAEKAAAEKAAADKKAAAEKAAADKKAAAAKAAAEKAAAAKAAAEADDIFGELSSGKNAPKTGGGAKGNNASPAGSGNTKNNGASGADINNYAGQIKSAIESKFYDASSYAGKTCTLRIKLAPDGMLLDIKPEGGDPALCQAALAAAKLAKIPKPPSQAVYEVFKNAPLDFKP
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity (PubMed:1683466, PubMed:8416897, PubMed:11115123, PubMed:11994151, PubMed:17233825).  The Tol-Pal system is also required for polar localization of chemoreceptors clusters (PubMed:24720726).  The system also appears to be required for the activity of several outer membrane-localized enzymes with cell wall remodeling activity (PubMed:32152098).  Is involved in the uptake of group A colicins (colicins A, E1, E2, E3, and K) and in the uptake of filamentous phage DNA (PubMed:1683466).
What are the official names of this protein?
Tol-Pal system protein TolA.
What is the protein family that this protein belongs to?
Belongs to the TolA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein. Note=Accumulates at cell constriction sites. Recruitment to the division site is dependent on FtsN activity.
Protein: DMAC1_MOUSE
Sequence: MGSSFSGSTEFSAPAPPTVSTAVPANPPAKSAVPASPARDPELKTCWSCRVLSGSTLFGAGTYVYLVARRPLKQGIPPGPGTVLQMVIGISIACWGVVVLVDPKGKSHPVI
What is the function of this protein?
Required for the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).  Involved in the assembly of the distal region of complex I.
What are the official names of this protein?
Distal membrane-arm assembly complex protein 1, Transmembrane protein 261.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SEPR_THESR
Sequence: MKRGGLWLLLGLLVLSACSSNPPAASTQEAPLLGLEAPEAIPGRYIVVYKENADVLPALEALKAALEPGLMQPQGLQAQALRTLGLEGARVDKVYTAALRGVAVEVPDQELARLRQDPRVAYIEADQEVRAFAVQSPATWGLDRIDQRTLPLDGRYTYTATGAGVHAYVVDTGILLSHQEFTGRIGKGYDAITPGGSAQDCNGHGTHVAGTIGGTTYGVAKGVTLHPVRVLDCNGSGSNSSVIAGLDWVTQNHVKPAVINMSLGGGASTALDTAVMNAINAGVTVVVAAGNDNRDACFYSPARVTAAITVGATTSTDYRASFSNYGRCLDLFAPGQSITSAWYTSSTATNTISGTSMATPHVTGAAALYLQWYPTATPSQVASALLYYATPNVVKNAGRYSPNLLLYTPF
What is the function of this protein?
Serine proteinase with preferred activity for amino acids with aromatic side groups at the P1' side of the scissible bond.
What are the official names of this protein?
Extracellular serine proteinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMFO_BACLD
Sequence: MNQTVNVIGAGLAGSEAAWQLAKRGINVRLYEMRPVKQTPAHHTDKFAELVCSNSLRANSLTNAVGVLKEEMRVLDSAIIAAADECSVPAGGALAVDRHEFAANVTEKVKNHPNVTVLHEEVTEIPEGPTIIATGPLTSEALSAKLRELTGEDYLYFYDAAAPIVEKDSLDMDKVYLKSRYDKGEAAYLNCPMTEEEFDRFYDALVSAETVPLKEFEKEIFFEGCMPIEVMAKRGKKTMLFGPMKPVGLEDPKTGKRPYAVVQLRQDDAAGTLYNIVGFQTHLKWGDQKEVLRLIPGLEQAEIVRYGVMHRNTFINSPSLLKATYQFKKRDDLFFAGQMTGVEGYVESAASGLVAGINAARLIQGKEPVTFSNETAIGSMAHYITETNKKNFQPMNANFGLFKELGVKIKNKQERNEQYASRALETIRNISKTL
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQEM_BACSU
Sequence: MIYQGFASVYDELMSHAPYDQWTKWIEASLPEKGRILDLACGTGEISIRLAEKGFEVTGIDLSEEMLSFAQQKVSSSQPILFLQQDMREITGFDGQFDAVVICCDSLNYLKTKNDVIETFKSVFRVLKPEGILLFDVHSSFKIAEVFPDSTFADQDEDISYIWQSFAGSDELSVIHDMSFFVWNGEAYDRFDETHEQRTFPVEEYEEMLKNCGFQLHRVTADFTDTEPSAQSERLFFKAQKSKTIVS
What is the function of this protein?
May be a S-adenosyl-L-methionine (SAM)-dependent methyltransferase.
What are the official names of this protein?
Putative methyltransferase YqeM.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: DAPA_SALPK
Sequence: MFTGSIVALVTPMDEKGNVSRSCLKKLIDYHVANGTSAIVSVGTTGESATLSHDEHGDVVMMTLELADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLTVTPYYNRPTQEGLFQHFKAIAEHTDLPQILYNVPSRTGCDMLPETVGRLAEIKNIIAIKEATGNLTRVHQIKELVSDDFILLSGDDASALDFMQLGGHGVISVTANVAAREMADMCKLAAEGQFAEARAINQRLMPLHNKLFVEPNPIPVKWACKALGLVATDTLRLPMTPITDHGRDIVKAALQHAGLL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFH_COXB1
Sequence: MISIIIAYSTPEKQVEIPLTVEESCTLVVAVKRSGILQQFPEINLSQAIVGIHNKRTALDAGLRDGDRIEIYRPLTMDPKQARLLRAKRGKIRRMVRGEAG
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: AROB_VIBPA
Sequence: MERITVNLAERSYPISIGAGLFEDPAYLSQVLSNKNTNQKVVVISNVTVAPLYADKILHQLKQLGCDASLLELPDGEQYKNLDVFNQVMNFLLEGSYARDVVIIALGGGVIGDLVGFASACYQRGVDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPKAVIIDTNCLSTLPEREFAAGIAEVIKYGIIYDGAFFDWLEENLDRLYTLDEDALTYAIARCCQIKAEVVAQDEKESGIRALLNLGHTFGHAIEAELGYGNWLHGEAVSSGTVMAAKTSLLRGLISEEQFERIVALLRRAKLPVHTPDSMSFDDFIKHMMRDKKVLSGQLRLVLPTGIGSAEVIADTSQEVIQQAIDFGRNI
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOA_ACIAD
Sequence: MSAITPYDWAIIAFVIGVTFLCVFMLTVPLLLGGKSWGRAKQEQFESGVVSAGGARIRLSAKFYLVAIFFVVFDLEALYLYAWATSVREVGWMGFTTMVIFVVDLLIALIYVFATGALTWSPSDRRKAAGIKPKIGSPNMNIAEITRFNSIEELVIDPTGHIPAQSSGRMKSKTSTAPSSKQE
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RAPA_PSEU2
Sequence: MAQQYQPGQRWISDSEAELGLGTVLAQDGRLLTVLYPATGETRQYALRNAPLTRVRFSPGDVITHFENWKMTVREVDDVDGLLVYHGLNAQNELVTLPETQLSNFIQFRLATDRLFAGQIDQLSWFSLRYNTLEHTSRQLQSSLWGLGGVRAQPIAHQLHIAREVADRIAPRVLLADEVGLGKTIEAGLVIHRQLLSGRASRVLILVPENLQHQWLVEMRRRFNLQVALFDAERFMESDAGNPFEDTQLALVALEWLVEDEKAQDALFAAGWDLMVVDEAHHLVWHEDKASREYSLVEQLAEVIAGVLLLTATPEQLGQDSHFARLRLLDPNRFHDLKAFRAESENYRPVAQAVQELLDKGKLSAAAQETIHGFLGAEGDSLLAAVNTGDEEAKSRLIRELLDRHGTGRVLFRNTRAAVQGFPERKLHQYPLPCPVEYLELPVGEHADLYPEVSFQSHSDVSEEERWWRFDPRVDWLIDTLKMLKRVKVLVICAHAETAMDLEDALRVRSGIPATVFHEGMNILERDRAAAYFADEEFGAQVLICSEIGSEGRNFQFSHHLVLFDLPSHPDLLEQRIGRLDRIGQKHTIELHVPFLETSPQARLFQWYHEALNAFLNTCPTGNALQHQFGPRLLPLLESGDDDKWQTLINEARSERERLESELHTGRDRLLELNSGGAGEGEALVEAILDQDDQFSLPIYMETLFDAFGIDSEDHSENALILKPSEKMLDASFPLGDDEGVTITYDRNQALSREDMQFITWEHPMVQGGMDLVLSGSMGNTAVALIKNKALKPGTVLLELIYVSEVVAPRSLQLGRYLPPAALRCLLDPNGNDLASRVSFNTLNDQLESVPRASANKFIQAQRDQLTPRINAGEEKIMPKHAERVAEAQRRLAADTEEELARLTALQAVNPTVRDSELVALRTQREQGLAMLEKAALRLEAIRVLVAG
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: PSBN_CUNLA
Sequence: METATLVAISISCLLVSFTGYALYTAFGQPSEQLRDPFEEHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ARAA_ECO24
Sequence: MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVNALNTEAKLPCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQFHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERIGSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDVNALVDEYESCYTMTPATQIHGEKRQNVLEAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAVEEKPILDVQHLGIGGKDDPARLIFNTQTGPAIVASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHHTVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: KYNU2_PHANO
Sequence: MDASAAISQLRQGQKPEWPQNANTSDFAKTLDNSSEFPKTLRHEYVVPTKAQLKRKTLNDDAQTAAKASSSDDEGIYFCGNSLGLQPKAVGEYLNAYLKTWGSIAVGSHFTPMADSPLTPFQDMAAECARRMSDIVGASPSEIVAMNTLTINLHLMMAAFYKPTEKKHKIMCEWRPFPSDWYAIESQIEWHGLDPKKSMLLVKPDDGYLMTTESILKLIDQEADELALIMLPGIQYYSGQLLDIPTITTHARKHGITIGWDLAHAAGNVELKLHDWDVDFACWCTYKYMNAGAGAIAGAFVHSKHGDNGSNVGLKGWYGHDKSSRFLMDNKFVPTPGAQGFQCSNPSAVDLTCLAGSLSVFQKTSVADLRSRSLLLTAYAEHLLTQIASRNIKDGNFPFQIISPLDPRFRGAQLSVLLQEDVMEEVFAGLEENGVICDKRKPGIIRVAPVPMYNTFEDVYKFMHILEGALQPKAEQKTQAHGEAVEARL
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase 2, Biosynthesis of nicotinic acid protein 5-2, L-kynurenine hydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF3_STAES
Sequence: MNLKEEIESRKTFAIISHPDAGKTTLTEKLLYFSGAIREAGTVKGKKTGKFATSDWMKVEQERGISVTSSVMQFDYDDYKINILDTPGHEDFSEDTYRTLMAVDSAVMVIDCAKGIEPQTLKLFKVCKMRGIPIFTFINKLDRVGKEPFELLDEIEETLNIDTYPMNWPVGMGQNFFGIIDRHSKTIEPFRDEENLLHLNEDYELKEEHAIKNDSAFEQAIEEMMLVDEAGEAFDNEALLNGELTPVFFGSALANFGVQNFLNAYVDHAPMPNARQTKEEVDVSPFDTDFSGFIFKIQANMDPKHRDRIAFMRVVSGAFERGMDVTLQRTNKKQKITRSTSFMADDKETVNHAVAGDIIGLYDTGNYQIGDTLVGGKQKYSFQELPQFTPEIFMKVSAKNVMKQKHFHKGIEQLVQEGAIQYYKTLHTNQIILGAVGQLQFEVFEHRMNNEYNVDVVMEPVGRKIARWIENEEDIKDNMNTSRSILVKDRYDNYVFLFENEFATRWFEEKFSDIKLYSLL
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRB_RALSO
Sequence: MTIEKTDAEWRDQLSDIEYRVTREAATERPFTGRYWDHWARGIYHCVCCGTPLFESSTKFDAGCGWPSYFAPINGEVIAEKTDHSHGMVRIEVQCKQCGAHLGHVFEDGPAPTGLRYCINSAALKFGD
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: TSAD_CALS8
Sequence: MLVLGIETSCDETAAAIVKDGREVLSNIVYSQIEIHNQFGGVVPEIASRKHVEKISYVADMALKEADIDIDKIDAVAATYGPGLVGSLLVGLSFAKALSYARKIPFIAINHIEGHIYANFITYPKLKPPLIVLVVSGGHTNLIILEDFDRYEVVGKTRDDAAGEAFDKIARYLGLGYPGGPAIDKVARHGDEEKYKYPLADVEGYNFSFSGLKSAVINHVHTLNQRRENFKVEDVAASFQKAVVDTLVEKTIKLSLESNIKRVAIAGGVAANSKLREELSKRCSEHQIEFYVPDFKYCTDNAAMIASAGYFKLIKGQTSSYSTNAVPYISLVSKKE
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDII4_ECO5C
Sequence: MAFNKDQDYWANIFVTPDFLSVETYSGLGMTGRDPLFSPRLLQPDVDDKSLGEEILQALSDSRTLDVLEERVAFFDLEKSKEQYAAWIATLMEKYGYRTKRALFKNMKKVGIHLVNDVITIRPSFHEKLEAWSGNRINESDYVVLPADSSPTEIGSGLRLALSRCKG
What is the function of this protein?
Expression of this locus confers protection against other bacteria carrying the locus.
What are the official names of this protein?
Immunity protein CdiI-o11, CdiI-o11-EC869.
Protein: EFTU_CHAGL
Sequence: MNIFRDKKTHINIATIGHFNHGKTTLSAAIAMTLANKKYRLDKKSIKVTLEEKNQGIGIYTHHFQYETTLRHYSHTDCPGHTDYINNMIAGISQVDSTILVVSAVDGSMSQTKEHLLIAKLLGISSFIVFINKEDQLDDDKFVYLVQKEISQFLMSHGFQTNKIPIVSGSALLALETLIQQPNVLRGENYWVDKIYTLIELLDSYIPKPKRKKDKHFLMWIDSVKFLPNIGPIAMGRIEQGTIKVGEFIDIVGFRETRTAKIISLEFFNQSCMQVLAGDDIGVSIEGTKNHNDIKKGMIISTPGTIKSWLEFEAQVYILKREEGGRTSPFFKGYCPQFFFKTTCVTGRIEAIEYTTGSKTWMIMPGDKLKIQVNLVYPIGIKKRMRFLIREGGVLVGVGIISNLIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, chloroplastic, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UBCB_DICDI
Sequence: MAAHKRLQKEITDMLKTPPSWCSAHLVDDNLQKWKATVQGPEGSPFEKGVFSMDIDIPADYPFKPPTLKFTTKIYHPNIKTSDGAICAEVFSTWSPQLKILDVLTTIRSILTDPNPDNPLETEIAQQFKTDRNAFNKTAKEWTKKYAK
What is the function of this protein?
Involved in protein ubiquitination and degradation during development.  Mediates protein ubiquitination at the mound and finger stage required for subsequent development and may be an essential component of the developmental transition between the induction of postaggregative gene expression and subsequent cell-type differentiation and morphogenesis.  ubcB and ubpB differentially control ubiquitination/deubiquitination and degradation of mkkA protein in a cell-type-specific and temporally regulated manner.
What are the official names of this protein?
Ubiquitin conjugating enzyme E2 B, E2 ubiquitin-conjugating enzyme B, UBC1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: ILVD2_BORPE
Sequence: MSDNNRSRHITEGVARAPNRAMYYALGYTEADFQNPMIGVANGHSTITPCNSGLQRLADAAIEAIRVSRANPQVFGTPTISDGMSMGTEGMKYSLVSREVIADCIETAAQGQWMDGVVVIGGCDKNMPGGMMALARMNVPGIYVYGGTIKPGHYKGKDLTIVSVFEAVGEYTMGRMDETDFKAIEQCAIPGSGSYGGMYTANTMSSAFEAMGMSLPYSSTMANEDQEKVASAAESARVLVEAVRRQLRPRDIITLASIENAVAVIMATGGSTNAVLHFLAIAHAAEVPWNIDDFERIRKRVPVICDLKPSGRYVATDLHRAGGIPQVMKILLNAGLLHGDCITITGKTVAETLANVPDAPPPGQDVIMPIERALYPQGHLAILKGNLSPEGCVAKITGLKNPVITGPARVFDSEDDAMAAIMDRRIRDGDVVVIRYEGPKGGPGMREMLAPTSALVGQGLGETVGLITDGRFSGGTWGMVVGHVAPEEFVGGPIALIREGDSVTIDAHQLLLLLLNISDEEMAARRKAWAQPKPRYVRGVLAKFGKLACTASRGAVTDAFEE
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase 2, DAD 2.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: METN1_BACHK
Sequence: MISFNNVSKVYESGGQSVHAVEDVTLSVEKGEIFGIIGFSGAGKSTLLRLVNMLERPTAGTISIDDKDITSLSTKELRKLRQRIGMIFQSFNLFNSRTVFGNIAYPLKLAKVPKNEIKERVNELLKFVGLEDKANNYPEQLSGGQKQRVGIARALATSPDILICDEATSALDPETTTEILNLLKKVNREYNLTILLITHEMHVVKEICHRVAVMEKGKVIEEGKLFDVFTQPKTKTTQNFVRSVINDHLPESVLAKIQNGGQIYRLTFTGEETGQPVLSYIAKNYNVDVNVLYGNIIELQNVLFGNLLVELQGEQREIQKALQHLRLQVQLKEVEAHAS
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RLMH_KORVE
Sequence: MKLRVVWIGKTKESAIQTLTGEYLKRLSRYVATEGLEIGSEEALLKLKDRPGRTAPVLVLMDERGKQVGSEELANFLGYHRDQGVQDLIFAIGPSDGWQKETLKSATQVLSMGKMTLPHELARVVLLEQLYRGYTILTGHPYHGGH
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y6545_BACAN
Sequence: MNTKGIIAKLTAGALIANLLICPANTLAEKKTFTDVPNWAQQSVNYLMKKALDGKPDGTFSPSEKIDRGSAAKLMAMVLGLQINKQAKPSFQDAKNHWASPYIAAVEKAGVIYGDGSGNFNPSKDIDRASMASMLVEAYKLNNRIIGDLPTQFEDLKGHWGAKLANALVALGISKGTGDGWKPNGIVTRAEAVQFIAQTDMKKADTSKRMYMNRHFITYHQPSLSSGVTSNQHAPQIIVVKEQRADGWIKIVTNIGDKWTPLYEKRETIHSTFTTYPEASHSSKVLGTHSPQTVTVIEEKGSWIRIRTNAGFQWLDKNQLTLPKKQNNFLEGKTIIIDPGHGGIDGGHKGIYMNESPVVYDTAVRVQKLFAQKTPFTALLTRDAYSRPGKNATDSLGKRVEFAKKNKGDIFVSIHANGFNGNAHGTETFYYKAPTQKSNPYVNDSRILAEKIQKRLITALQTRDRGVKIGNLYVLRENTMPSVLTELGFVDNKADGKKLDSPEWRQRAAEAIYAGILDYYEWKGHNMSAYY
What are the official names of this protein?
Uncharacterized cell wall amidase pXO2-42/BXB0045/GBAA_pXO2_0045.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the N-acetylmuramoyl-L-alanine amidase 3 family.
What are the subcellular locations of this protein?
Secreted, cell wall, S-layer.
Protein: RL2_STRZP
Sequence: MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRNNNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKAYIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGASAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRPTVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNEK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: SCRR_SALTM
Sequence: MKTKRVTIKDIAEQAGVSKATASLVLNGRGKELRVAQETRERVLSIARKHHYQPSIHARSLRNNRSHTIGLVVPEITNHGFAVFAHELEMLCREAGVQLLISCTDENPGQESVVVNNMIARQVDGMIVASCMHNDADYLKLSQQLPVVLFDRCPNESALPLVMTDSITPTAELISRIAPQHSDEFWFLGGQARLSPSRDRLTGFTQGLAQAGIALRPEWVINGNYHPSSGYEMFAALCARLGRPPKALFTAACGLLEGVLRYMSQHHLLDSDIHLTSFDDHYLYDSLSLRIDTVQQDNRQLAWHCYDLISQLIEGDTPETLQRYLPATLQFRHQ
What is the function of this protein?
Repressor for the scr operon.  Binds D-fructose as an inducer.
What are the official names of this protein?
Sucrose operon repressor, Scr operon regulatory protein.
Protein: 3MGH_LACDA
Sequence: MDYRNFFTGRPTSEICRDLIGRPFYYQAGGEKIGGYIVESEAYLGIYDRAAHSYGGRRSHANEGLWRAGGTIYIYSQRQYVFFDIACQEEGNPQGVLIRAIEPVWGLDQMLKNRGGKDGVLLTNGPAKLMQAMGIKSRNWDLAPLADSPFVIDLTEKKPAKEIVASPRIGIVQADPAWAQAPLRYYVAGNPYVSGMKKRDWADDHGWL
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: GLUB5_ORYSJ
Sequence: MATIAFSRLSIYFCVLLLCHGSMAQLFGPNVNPWHNPRQGGFRECRFDRLQAFEPLRRVRSEAGVTEYFDEKNEQFQCTGTFVIRRVIEPQGLLVPRYSNTPGMVYIIQGRGSMGLTFPGCPATYQQQFQQFLPEGQSQSQKFRDEHQKIHQFRQGDIVALPAGVAHWFYNEGDAPVVALYVFDLNNNANQLEPRQKEFLLAGNNNREQQMYGRSIEQHSGQNIFSGFNNELLSEALGVNALVAKRLQGQNDQRGEIIRVKNGLKLLRPAFAQQQEQAQQQEQAQAQYQVQYSEEQQPSTRCNGLDENFCTIKARLNIENPSHADTYNPRAGRITRLNSQKFPILNLVQLSATRVNLYQNAILSPFWNVNAHSLVYIVQGHARVQVVSNLGKTVFNGVLRPGQLLIIPQHYVVLKKAEHEGCQYISFKTNANSMVSHLAGKNSIFRAMPVDVIANAYRISREQARSLKNNRGEELGAFTPRYQQQTYLGFSNESENEASE
What is the function of this protein?
Seed storage protein.
What are the official names of this protein?
Glutelin type-B 5.
What is the protein family that this protein belongs to?
Belongs to the 11S seed storage protein (globulins) family.
Protein: TNFA_SHEEP
Sequence: MSTKSMIRDVELAEEVLSNKAGGPQGSRSCWCLSLFSFLLVAGATTLFCLLHFGVIGPQREEQSPAGPSFNRPLVQTLRSSSQASNNKPVAHVVANISAPGQLRWGDSYANALMANGVELKDNQLVVPTDGLYLIYSQVLFRGHGCPSTPLFLTHTISRIAVSYQTKVNILSAIKSPCHRETLEGAEAKPWYEPIYQGGVFQLEKGDRLSAEINLPEYLDYAESGQVYFGIIAL
What is the function of this protein?
The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
What are the official names of this protein?
Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Tumor necrosis factor, membrane form]: Membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Tumor necrosis factor, soluble form]: Secreted. SUBCELLULAR LOCATION: [C-domain 1]: Secreted. SUBCELLULAR LOCATION: [C-domain 2]: Secreted.