PharMolix/UniProtQA huggingface dataset:
Protein: RAB31_HUMAN
Sequence: MAIRELKVCLLGDTGVGKSSIVCRFVQDHFDHNISPTIGASFMTKTVPCGNELHKFLIWDTAGQERFHSLAPMYYRGSAAAVIVYDITKQDSFYTLKKWVKELKEHGPENIVMAIAGNKCDLSDIREVPLKDAKEYAESIGAIVVETSAKNAINIEELFQGISRQIPPLDPHENGNNGTIKVEKPTMQASRRCC
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.  Required for the integrity and for normal function of the Golgi apparatus and the trans-Golgi network.  Plays a role in insulin-stimulated translocation of GLUT4 to the cell membrane.  Plays a role in M6PR transport from the trans-Golgi network to endosomes.  Plays a role in the internalization of EGFR from the cell membrane into endosomes.  Plays a role in the maturation of phagosomes that engulf pathogens, such as S. aureus and M. tuberculosis.
What are the official names of this protein?
Ras-related protein Rab-31, Ras-related protein Rab-22B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network. Golgi apparatus, trans-Golgi network membrane; Lipid-anchor; Cytoplasmic side. Early endosome. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Note=Rapidly recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211).
Protein: PSN1_CANLF
Sequence: MTELPAPLSYFQNAQMSEDNHLSNTVRSQNDSREQHSSERRRRGNPEPLSNGRPQGSSHQVVEQDDEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFLFSFIYLGEVFKTYNVAMDYITVALLIWNFGVVGMIAIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEGDPEAQRKVSKNSNYNAQSTESETQDPVTESDDGGFSEEWEAQRDSRLGPHHSTTETRAAVQELSSNILASEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI
What is the function of this protein?
Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein).  Requires the presence of the other members of the gamma-secretase complex for protease activity.  Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels.  Stimulates cell-cell adhesion via its interaction with CDH1; this stabilizes the complexes between CDH1 (E-cadherin) and its interaction partners CTNNB1 (beta-catenin), CTNND1 and JUP (gamma-catenin).  Under conditions of apoptosis or calcium influx, cleaves CDH1.  This promotes the disassembly of the complexes between CDH1 and CTNND1, JUP and CTNNB1, increases the pool of cytoplasmic CTNNB1, and thereby negatively regulates Wnt signaling (By similarity).  Required for normal embryonic brain and skeleton development, and for normal angiogenesis (By similarity).  Mediates the proteolytic cleavage of EphB2/CTF1 into EphB2/CTF2 (By similarity).  The holoprotein functions as a calcium-leak channel that allows the passive movement of calcium from endoplasmic reticulum to cytosol and is therefore involved in calcium homeostasis.  Involved in the regulation of neurite outgrowth (By similarity).  Is a regulator of presynaptic facilitation, spike transmission and synaptic vesicles replenishment in a process that depends on gamma-secretase activity.  It acts through the control of SYT7 presynaptic expression (By similarity).
What are the official names of this protein?
Presenilin-1, PS-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase A22A family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic granule. Cell membrane; Multi-pass membrane protein. Cell projection, growth cone. Early endosome. Early endosome membrane; Multi-pass membrane protein. Cell projection, neuron projection. Cell projection, axon. Synapse. Note=Translocates with bound NOTCH1 from the endoplasmic reticulum and/or Golgi to the cell surface. Colocalizes with CDH1/2 at sites of cell-cell contact. Colocalizes with CTNNB1 in the endoplasmic reticulum and the proximity of the plasma membrane. Also present in azurophil granules of neutrophils. Colocalizes with UBQLN1 in the cell membrane and in cytoplasmic juxtanuclear structures called aggresomes.
Protein: GATC_BACAN
Sequence: MSRISVENVKHVAHLARLAITDQEAEKFQKQLDAIVTFAEQLNELDTTDVKPTTHVLTMKNVMREDVPEKGLPVEEVLKNAPDHKDNQIRVPAVLE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: DCUP_SODGM
Sequence: MSELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAEAGDFMSLCRNADLACEVTLQPLRRFPLDATILFSDILTVPDAMGLGLWFEQGEGPRFARPIQHRRDVEQLPIPDPEQELGYVMNAVRAIRQRLQGAVPLIGFSGSPWTLATYMVEGGSSKAFTKIKQMLYAEPETLHLLLDKLADSVVLYLNGQIRAGAQAVMLFDTWGGALTGADYREFSMHYMHKIVDGLLREQDGRRVPVTLFTKGGGQWLEAMAATGCDALGLDWSTDIADARRRVGDKVALQGNMDPSVLYGSPARIEREVATILDAFGPGEGHVFNLGHGIHQDVPPAHAGHFVAAVHRLSQSYHR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_XANC8
Sequence: MSINKNIARLRRAKSTRAHIRELGVARLSVLRTGQHLYAQVFTADGSKVIAAANTLQADVKDGLKNGKNSDAAVKVGKLIAERAKAAGIEKVAFDRSGYRYHGRIKALADAAREGGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: PROT2_ORYSJ
Sequence: MNIDMANSDDKALISEDTAHQISADPWYQVGFVLTTGVNSAYVLGYSGSVMVPLGWIGGTCGLILAAAISLYANALLARLHEIGGKRHIRYRDLAGHIYGRKMYSLTWALQYVNLFMINTGFIILAGQALKATYVLFRDDGVLKLPYCIALSGFVCALFAFGIPYLSALRIWLGFSTFFSLIYITIAFVLSLRDGITTPAKDYTIPGSHSARIFTTIGAVANLVFAYNTGMLPEIQATIRPPVVKNMEKALWFQFTVGSLPLYAVTFMGYWAYGSSTSSYLLNSVKGPVWVKAMANLSAFLQTVIALHIFASPMYEFLDTKYGSGHGGPFAIHNVMFRVGVRGGYLTVNTLVAAMLPFLGDFMSLTGALSTFPLTFVLANHMYLMVKRHKLSTLQISWHWLNVAGFSLLSIAAAVAALRLIMVDSRTYHLFADL
What is the function of this protein?
Proline transporter that mediates proline transport across the plasma membrane.
What are the official names of this protein?
Probable proline transporter 2.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. Amino acid/auxin permease (AAAP) (TC 2.A.18.3) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HSCB_RICCK
Sequence: MQNYFQLLGLQQDYNIDLKILEKQYFAMQVKYHPDKAKTLQEKEQNLIIAAELNKAYSTLKDALKRAEYMLLLQNINLNDQKARTLLSSLELSIFWDEMEIIENTTICSDLEKIKAKYELMEKHEIDSLKQAFEEQNLSDATIKTSKLKYIGTLLNKLQKKIKSCK
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: CHFR_PONAB
Sequence: MERPEEGKQSPPPQPWGRLLRLGAEEGEPYVLLRKREWTIGRRRGCDLSFPSNKLVSGDHCRIAVDEKSGQVTLEDTSTSGTVINKLKVVKKQTCPLQTGDVIYLVYRKNEPEHRSGGGGISPKGSGPSVASDEVSSFATALPDRKTASFSSLEPQDQEDLEPMKKKMRGDGDLDLNGQLLVAQPRRNAQTVHEDVRAAAGKPDKMEETLTCIICQDLLHDCVSLQPCMHTFCAACYSGWMERSSLCPTCRCPVERICKNHILNNLVEAYLIQHPDKSRSEEDVQSMDARNKITQDMLQPKVRRSFSDEEGSSEDLLELSDVDSESSDISQPYVVCRQCPEYRRQAAQPPPCPAPEGEPGVPQALVDAPSTSVSLTTVQDYVCPLQGSHALCTCCFQPMPDRRAEREQNPRVAPQQCAVCLQPFCHLYWGCTRTGCFGCLAPFCELNLGDKCLDGVLNNNSYESDILKNYLATRGLTWKNMLTESLVALQRGVFLLSDYRVTGDTILCYCCGLRSFRELTYQYRQNIPASELPVAVTSRPDCYWGRNCRTQVKAHHAMKFNHICEQTRFKN
What is the function of this protein?
E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtubule poisons.  Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus.  Probably involved in signaling the presence of mitotic stress caused by microtubule poisons by mediating the 'Lys-48'-linked ubiquitination of target proteins, leading to their degradation by the proteasome.  Promotes the ubiquitination and subsequent degradation of AURKA and PLK1.  Probably acts as a tumor suppressor, possibly by mediating the polyubiquitination of HDAC1, leading to its degradation.  May also promote the formation of 'Lys-63'-linked polyubiquitin chains and functions with the specific ubiquitin-conjugating UBC13-MMS2 (UBE2N-UBE2V2) heterodimer.  Substrates that are polyubiquitinated at 'Lys-63' are usually not targeted for degradation, but are rather involved in signaling cellular stress.
What are the official names of this protein?
E3 ubiquitin-protein ligase CHFR, Checkpoint with forkhead and RING finger domains protein, RING-type E3 ubiquitin transferase CHFR.
What is the protein family that this protein belongs to?
Belongs to the CHFR family.
What are the subcellular locations of this protein?
Nucleus, PML body.
Protein: Y2210_EXIS2
Sequence: MEAYLFLIGLVLIGVIAQNKSLIIAAAFLLIIKAIGLDGRLFPSLQAKGITWGVTLITAAILVPIATGDIGFRELLNSVRGHIGIISFLAGIFVAIIAAHGVGLMKEDPLVTTALLAGTILAVGLFRGVPVGPLIGAGIAALVIGMWDIIVKAISG
What are the official names of this protein?
UPF0756 membrane protein Exig_2210.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PETD_PHYPA
Sequence: MGVTKKPDLSDPVLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACTVGLAVLEPSMIGEPANPFATPLEILPEWYFFPVFQILRTVPNKLLGVLLMAAVPAGLLTVPFLENVNKFQNPFRRPVATTVFLIGTVVSIWLGIGAALPIDISLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: AB12B_ARATH
Sequence: MNRDGAGEGDSVSHEHSTSKTDEKAKTVPLYKLFAFADSFDVFLMICGSLGAIGNGVCLPLMTLLFGDLIDSFGKNQNNKDIVDVVSKVCLKFVYLGLGRLGAAFLQVACWMITGERQAAKIRSNYLKTILRQDIGFFDVETNTGEVVGRMSGDTVHIQDAMGEKVGKFIQLVSTFVGGFALAFAKGWLLTLVMLTSIPFLAMAGAAMALLVTRASSRGQAAYAKAATVVEQTIGSIRTVASFTGEKQAINSYKKYITSAYKSSIQQGFSTGLGLGVMIYVFFSSYALAIWFGGKMILEKGYTGGSVINVIIIVVAGSMSLGQTSPCVTAFAAGQAAAYKMFETIKRKPLIDAYDVNGKVLGDIRGDIELKDVHFSYPARPDEEIFDGFSLFIPSGATAALVGESGSGKSTVINLIERFYDPKAGEVLIDGINLKEFQLKWIRSKIGLVCQEPVLFSSSIMENIAYGKENATLQEIKVATELANAAKFINNLPQGLDTKVGEHGTQLSGGQKQRIAIARAILKDPRVLLLDEATSALDTESERVVQEALDRVMVNRTTVVVAHRLSTVRNADMIAVIHSGKMVEKGSHSELLKDSVGAYSQLIRCQEINKGHDAKPSDMASGSSFRNSNLNISREGSVISGGTSSFGNSSRHHSLNVLGLFAGLDLGSGSQRVGQEETGTTSQEPLRKVSLTRIAALNKPEIPVLLLGTVVAAINGAIFPLFGILISRVIEAFFKPADQLKKDSRFWAIIFVALGVTSLIVSPSQMYLFAVAGGKLIRRIQSMCFEKAVHMEVSWFDEPENSSGTMGARLSTDAALIRALVGDALSLAVQNAASAASGLIIAFTASWELALIILVMLPLIGINGFLQVKFMKGFSADAKSKYEEASQVANDAVGSIRTVASFCAEEKVMQMYNKQCEGPIKDGVKQGFISGLGFGFSFFILFCVYATSFYAAARLVEDGKTTFIDVFQVFFALTMAAIGISQSSTFAPDSSKAKVAAASIFAIIDRKSKIDSSDETGTVLENVKGDIELRHLSFTYPARPGIQIFRDLCLTIRAGKTVALVGESGSGKSTVISLLQRFYDPDSGQITLDGVELKKLQLKWLRQQMGLVGQEPVLFNDTIRANIAYGKGSEEAATESEIIAAAELANAHKFISSIQQGYDTVVGEKGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERLVQDALDRVIVNRTTVVVAHRLSTIKNADVIAIVKNGVIAENGTHETLIKIDGGVYASLVQLHMTASN
What are the official names of this protein?
ABC transporter B family member 12, ABC transporter ABCB.12, AtABCB12, Multidrug resistance protein 16, P-glycoprotein 12.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LCDC_ANAPI
Sequence: MYTLGIDVGSASSKAVILKDGKDIVAAEVVQVGTGSSGPQRALDKAFEVSGLKKEDISYTVATGYGRFNFSDADKQISEISCHAKGIYFLVPTARTIIDIGGQDAKAIRLDDKGGIKQFFMNDKCAAGTGRFLEVMARVLETTLDEMAELDEQATDTAPISSTCTVFAESEVISQLSNGVSRNNIIKGVHLSVASRACGLAYRGGLEKDVVMTGGVAKNAGVVRAVAGVLKTDVIVAPNPQTTGALGAALYAYEAAQKK
What is the function of this protein?
Required for the activation of lactoyl-CoA dehydratase.  This protein is extremely sensitive towards oxygen.
What are the official names of this protein?
Activator of lactoyl-CoA dehydratase, Lactoyl-CoA dehydratase component E I.
Protein: NPY_CHICK
Sequence: MQGTMRLWVSVLTFALSLLICLGTLAEAYPSKPDSPGEDAPAEDMARYYSALRHYINLITRQRYGKRSSPETLISDLLLRESTENIPRSRFEDPSMW
What is the function of this protein?
NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.
What are the official names of this protein?
Pro-neuropeptide Y.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle.
Protein: SAES_STAAN
Sequence: MVLSIRSQIIIGVVSSILLTSTILAIAYILMWFNGHMTLTLTLTTIITSCLTLLICSIFINPLIQKIKQFNIKTKQFANGNYASNDKTFNSPKEIYELNQSFNKMASEITQQMNQIKSEQQEKTELIQNLAHDLKTPLASIISYSEGLRDGIITKDHEIKESYDILIKQANRLSTLFDDMTHIITLNTGKTYPPELIQLDQLLVSILQPYEQRIKHENRTLEVNFCSEIDAFYQYRTPLERILTNLLDNALKFSNVGSRIDINISENKDQDTIDIAISDEGIGIIPELQERIFERTFRVENSRNTKTGGSGLGLYIANELAQQNNAKISVSSDIDVGTTMTVTLHKLDITS
What is the function of this protein?
Member of the two-component regulatory system SaeR/SaeS involved in the regulation of staphylococcal virulence factors in a strain-dependent fashion.  Probably functions as a membrane-associated protein kinase that upon sensing the appropriate signal, autophosphorylates and in turn activates the cytosolic response regulator SaeR (By similarity).
What are the official names of this protein?
Histidine protein kinase SaeS, Sensor protein SaeS, Staphylococcus exoprotein expression protein S.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL29_BUCCC
Sequence: MNIIEKNNIDKNHLKKNLLDLLKEQFNIRLQLSSGKLKKTHLVKKNKKDIARIKTVLNKRINHTL
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: CATA1_HORVU
Sequence: MDPYKHRPTSGANSAYWTTNSGAPVWNNNNALTVGHRGPILLEDYHLIEKLAQFDRERIPERVVHARGASAKGFFEVTHDVSQLTCADFLRAPGVQTPVIVRFSTVVHERGSPETLRDPRGFAVKFYTREGNFDLVGNNMPVFFIRDGMKFPDMVHAFKPSPKTNMQENWRVVDFFSHHPESLHMFTFLFDDVGIPLNYRHMDGFGVNTYTLISRDGKAHLVKFHWKPTCGVKCLLDDEAVTVGGTCHTHATKDLTDSIAAGNYPEWKLFIQTIDADHEDRFDFDPLDVTKTWPEDIIPLQPVGRMVLNKNIDNFFAENEQLAFCPAVTVPGIHYSDDKLLQTRIFSYADTQRHRLGPNYLMLPVNAPKCAHHNNHHDGLMNFIHRDEEVNYFPSRFDPTRHAEKYPMPPRVLSGCREKCIIDKENNFKQAGERYRSFDPARQDRFLQRWVDALTDARVTHEIQSIWVSYWSQCDASLGQKLASRLKIKPNM
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase isozyme 1.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome. Glyoxysome.
Protein: PLSX_BART1
Sequence: MIRISVDVMGGDYDPEVAIAGAAIVQKYLSNIYFLFYGIEEVVKPVLKKYPCLDSISRFFPTESYTRMDEKPSQALRNGRGKSSMWYAIEAVKNGEADACVSAGNTGALMAMSYFCLKMLAEAERPGIAGIWPTLRSESIVLDIGATIGASASQLVDLAVMGAGMFRALYHTEKPSVGLLNVGVEEAKGLYEIKKAGMILREVQLEGLEYKGFVEGNDIGKGTVDVVVTEGFSGNIALKTAEGTARQIAEILNSAMRSSFLTSLGYFLSRRAFRTLKNKMDPDRVNGGVLLGLNGVVIKSHGSANANGFASAIRVGYEMVNNGLLKKITADLRRFHENKETLFDQEDEAAMSGESL
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: FAR9_HEMMO
Sequence: GRGGASNYVRL
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-9, FMRFa-9.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ACKA_SALTY
Sequence: MSSKLVLVLNCGSSSLKFAIIDAVNGDEYLSGLAECFHLPEARIKWKMDGSKQEAALGAGAAHSEALNFIVNTILAQKPELSAQLTAIGHRIVHGGEKYTSSVVIDESVIQGIKDSASFAPLHNPAHLIGIAEALKSFPQLKDKNVAVFDTAFHQTMPEESYLYALPYSLYKEHGVRRYGAHGTSHFYVTQEAAKMLNKPVEELNIITCHLGNGGSVSAIRNGKCVDTSMGLTPLEGLVMGTRSGDIDPAIIFHLHDTLGMSVDQINKMLTKESGLLGLTEVTSDCRYVEDNYATKEDAKRAMDVYCHRLAKYIGSYTALMDGRLDAVVFTGGIGENAAMVRELSLGKLGVLGFEVDHERNLAARFGKSGFINKEGTRPAVVIPTNEELVIAQDASRLTA
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.  Has broad substrate specificity and can also utilize GTP, UTP and CTP.  Can also phosphorylate propionate, but has very low activity with formate and is inactive with butyrate.
What are the official names of this protein?
Acetate kinase AckA, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSA_METM7
Sequence: MQQMVPASGYDRAITIFSPEGRLYQVEYAREAVRRGTTAVGIKCKDGVVLAVDRRITSKLIDVSSIEKIFQIDDHIVAATSGLVADARVLIDRARLEAQMNRISYGEAITVEALAKKICDIKQAYTQHGGARPFGLALLITGIDRHSARLFETDPSGALIEYKATAIGSGRPIAMEVLESKYDENMTVNEGMELALYALSKTTEELKPENIDMAIVKDSGKLVEKISVDEIEKIVKAVYKKVEAEEAEAEKNKGEEDIE
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PsmA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y946_ARCFU
Sequence: MKRVGLIGVIMAALLVISATPVMAGVSVKVSVNTTYPGELTVENFNLTPTYGRVPLTINITDVYLKNTNLTTPLSGTVYLYVNGQIKNNYYCSVTQTNNTTSWMSCGIEYTITDTSQTNISVGNKTDYLQNVTLTLWTTQLPESYVPQIPTLDLKDDGPISVDVLKIPSLKLSDDQVNVGETVTIEANWNYYAKEDGTRRIAVVSWADYRNIRSGATIDVATLLDKSKMTISLPEDGGSNSWDFTPTEPGYYVVVAFVDDTNFSDVLVFRATPTAAEKPTVSISVSKSVVALGDYIKVGASMSTDQAVKPIAVFITGANQTEVLCSYPEPGASTVGAWTVKEACGDDEWWIQIKDRPEGVYVAKIDVGEGELRAEATAVFQVVKPKILSLDVPSQHVKGQDLVITGTTNLAKSGTEDDSGSNAAENKAYLVIKDLSGKEVFNDTLSNQVYDSTGGKVKSNAVSLIDSDGSFKFKIDYFGKYFATETGFYIAEVKIQSDSLGEYTDTETATFEVVKPELKLIADKTTVTRGDTVTFTIDTNLKINSEVKFKIDDLAFCSGDPDCDVKEKTYYVDALGDVVIKLDVNTEAPLTDYKFTAEIPGLGISTDIRVSVVKQTLDISVDRTTVPRGGDIRVTGSSTADGVYIYASDSGVFTVGDTPVPDVDLKTKGSKINTTDVPYMEPDDNDNIDFQISVNVTGVETGTYYLYFYAPANISVVDKASDPQKIIAVTVTDPQIVEVTAPSKVPYQSKFEVSVLTDPGDRDNVEVRLVLSGPNVRDTTVADWASVDTNNYFNKTVDLRDIAKNKLNLDALEPGLYVLTAELRFKQSLGGEKVDSEDKLIEILGLTFEVDVNTPVVIGDEIVVNITTDRLEAGYDKIFVTLVGTNYKVTQVATLNSEGKATVTFETYGMSAGTYKVYVRDTMDTCSETDQYTWVDEHYMLDPASELAPMYKADDDVLVIKTIELLETAPTTTTVVTTTTAVTTTTVATTTTAVETTTTEAVTTTTEAQQGGGVPGFEAVFAIAGLLAVAYLLRRK
What are the official names of this protein?
Uncharacterized protein AF_0946.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RETM_DROPS
Sequence: MVQKFQSPVRVYKYPFELVMKAYERRFPKCPQMPIVLDCDVIKIESLENGAKTNTTRRCKLAVDAPYIFKKLIGVDFVYFLQHNYLDMSNRTLSIEAVNESFSSRIEIFERCRYYAHPDNAEWTCFDQTATLDIKNFFGFEHSMEKMGMKQYTQTTLKGKEIIEYFINQLEQEGVTHVDRWVPPLDAAKSPTPEQKQHHDILLDGDFIARNLGQLSPMQESKLLELRKMLDGVDDLERVPSYQTILRFLSARDWHVSQAFAMLCDSLQWRKEHRMDSLLEEYTEPAVVVEHFPGGWHHHDKDGRPIYILRLGHMDVKGLLKSLGMEGLLRLALHICEEGIQKINESAERLDKPVLNWSLLVDLEGLSMRHLWRPGIKALLYIIETVERNYPETMGRVLVVRAPRVFPIAWTIVSAFIDEHTRSKFLFYGPDCEHMKDGLAQYIDEEIVPDFLGGPCKTMIHEGGLVPKTLYKANSLEDHDDDVTIVSPGAGAATATASAEASLAPVALAPMKRLSANHQHDHQNLYKSVDLKPGFSHELLIRNEDPKSVLTWDFDVMRNDLHFTLYRVTQELPEKNDDAVSYFDLQDFVEGTNYFREEPTLICRHKESVQGSHVMHHNDSYLMHWFSPSGAQLNLFYEVLSSVNYKGSMTSLQSAFSSNSSAASSVQSR
What are the official names of this protein?
Protein real-time.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: KCY_BRUA2
Sequence: MKSFVVAPFIVAIDGPAASGKGTLARRIATHYGMPHLDTGLTYRAVAKALLDKGLPLDDEALATDAALSLDLLAMDKAVLSAHAIGEAASKVAVMPAVRRALVEAQRHFANALPSSVLDGRDIGTVVCPDAAIKLFVTASPEVRARRRFDEVLARGDTADFAEILADLKKRDERDMNRTDSPLRPAEDAHLLDASEMSIEAAFLAAKKLIDHALAQHRG
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMC_ACTSZ
Sequence: MNCPHYQTQTCISCRWLETPYADQLTQKQTHLQQQISILDQSRLEWIPPFQSAQSGFRNKAKMVVNGTVERPILGIINERNQPADLTDCPLYPARFAEIFSVLKDFIGRAGLVPYNIAKQKGELKYILLTESRANQTLMLRFVLRSETKLPLMRRELAGLSTKIPDLAVVTANIQPQHAAILEGQKEIFLTEQQVLEERFNGIPLFIRPQGFFQTNPAVAEGLYGTAQNWVKNLPVQRLWDLFCGVGGFGLHCAAALQANTPDVALTGIEISPSAIYSAALSAEKCGLKNVSFQSLDAANFALNQDDKPDLVIVNPPRRGIGKPLAEFLNNLRPQFLLYSSCNAVTMGSDLQSLTHYQMRKIRLFDMFPHTAHYEVLTLLTLK
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC, 23S rRNA(m5U747)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
Protein: RL16_SYNJA
Sequence: MLSPKRTKYRKQQRGRMKGKATRGNRINFGEYGLVALEPAWITARQIEASRRAMARYVRRGGQIWIRIFPDKPVTQRPAETRMGSGKGNPEYWVCVVKPGRILFEMGGVPEATAREAMRLAAQKLPIKVKFVTKANFEEPEPVQKAAPETTEVAASAI
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.