PharMolix/UniProtQA huggingface dataset:
Protein: SET1_DICDI
Sequence: MENETIVDNSLNNKSNVNNSNNDINNSKSNNNNTNTNYNNNHNNTTTTTTINKTEEKQNDSPKDSEFEFLDELKGVDDQHHVFSSEDESYTNGNKKRKQTDTPLSPNQDLKKRSITSPTTSPTTSTSTSTSTSTSTSTSTIINNNNNNLKDKTKEEIEFIKHIRSQLVKPKFLKDKPNFPLRSSGGNWIFVGKLPSLQSTTTDNTTLMSPNNATTTNGSSSNISTTTTTTTTTTPTTKILYRVNGFLSDNETIDSIEINFGDPRDRYEIERLHSSRINNPFELPCVSFKNPLFIKSNIAKDIGISNEYGGMNDSFEFSNQPPPPSPPPPPPPTLPPPPPPTLPPQHSLEQQSTKQQIFTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQIPKINQQHYSTQPSVLIDDIYDPSNPTEPISPHQDHYPNFIFSKLQRYEHLPTRNPISQYDYRDRPRDWERDRDRDWERDRDWERDRDRERDRDRDRDWERDRDWERDRDWERDRDRDRDWERDRDRDWERDRDRDWERDRERDRDRYDRQTNFSPAPQSTTTSASTSSTTSSTDKNSNNTTSTSVSATTSTTKRKSKFSEPIEPSPFAIQIPRDNIKINGNLINNSSSSSSSGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNSDVKDIKDKLLKQFKIYDPVNVYMDESYWYIDFRSSESRERAIQVLNGSFIDTWKLNVDNKKTNTINEELQKQKQLENDSNNNKPNNFNLLENERSLKEICKLLVATELLSTSSKDISKNFIEAEILKTIKLLDSQRIDPLTQNSTIINNTTNTTTSNINNTSNNTTVTPIVTPKSIISAPTSRDSPRGGRSSSTTTKKPSKLDLNGSGVPPTLKKLDTIKQQQQPQPPLSPLKRPPKSHFYSDSEDDGNNNNDDDDDDDDDEDDDFDQELSPLHSSRDSKKNIKSIIKKKPIYSDDDDDHYHHHNHHHNHHHHHHHDRSEVELYNESDLQVDVLDSDNENQDESDYHKSSDNFGHVELSDDDNEFDSLDTDQDLYDTEENDNGKKSNKRPRKSKFNGKSKKPTTTTSTTTTATKSKGRSKKTTITTPTHNIPVLDEIQSNLDDEDASYVSMVMAADKDIKLLFSTKSEEGFEDSSQEILSTPTRTKPSRNRKERNLPFLDEEDDESFKQLPQPQQKQEKQEKHEHKLKNKELKQKNNEVIINKTEEHFSENLNGDNNNNNDKSENENENENENKNENENDNNNLNTSIDNINGVERRSITGCARSEGYTRSDIQKLFKRKQVAPTGKRGAASSASSGSNSSSSSTAESFETGGNLSKSARSSRFDNRGFGSDPITLASLKSRRKRIKFERSDIHDWGLFAMETISAKDMVIEYIGEVIRQKVADEREKRYVKKGIGSSYLFRVDDDTIIDATFKGNLARFINHCCDPNCIAKVLTIGNQKKIIIYAKRDINIGEEITYDYKFPIEDVKIPCLCKSPKCRQTLN
What is the function of this protein?
Histone methyltransferase that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3.  May act to regulate chromatin-mediated events.
What are the official names of this protein?
Histone-lysine N-methyltransferase set1, Histone H3 lysine 4 methyltransferase, SET domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RSMJ_YERP3
Sequence: MSHVSICLLSEAGADPGALSILADRWGLVSDDQAVMALVLTAERLELRKRDEPKLGGIYVDFVSGTQAHRRKFGGGRGEAVAKAVGIKKGYLPRVVDATAGLGRDAFVLAALGCQVQMLERNPVVAALLDDGLRRGYLDAEIGPWLRERLTLLHASSLTALVAIEPRPEVVYLDPMYPHRQKSALVKKEMRVFQSLVGADNDADGLLAPARALATKRVVVKRPDYAEPLAGVAAQAAVVTKSHRFDIYPSSVTPPR
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNT_SALTI
Sequence: MSDNAQLSGLCDRFRGFYPVVIDVETAGFNAKTDALLEIAAITLKMDEQGWLMPDMTLHFHVEPFAGANLQPEALAFNGIDPSNPLRGAVSEYEALHAIFKMVRKGIKDSGCSRAIMVAHNATFDHSFMMAAAERASLKRNPFHPFVTFDTAALSGLALGQTVLSKACLAAGMEFDGEKAHSALYDTERTAVLFCEIVNRWKRLGGWPLPLPTDK
What is the function of this protein?
Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang.  Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A).  Also appears to be involved in tRNA biosynthesis.
What are the official names of this protein?
Ribonuclease T, Exoribonuclease T, RNase T.
What is the protein family that this protein belongs to?
Belongs to the RNase T family.
Protein: MUTS_PARDP
Sequence: MSDQPTPMMAQYLAIREANPGALLFYRMGDFYEMFFEDAVAAAAALDIALTKRGTHLGEPIPMCGVPVHAAESYLLTLIRKGFRVAIAEQMEDPAEAKKRGSKSVVARDVVRLVTPGTLTEESLLEARRHNFLASFASVRDESALAWVDISTGAFRVMPCPPARLAPELARHAPRELLAAEGANLDEIAAEAGAALTELPGGSFDSSAATRRLCALFSVETLDGFGQFSRAELAAMGAIADYLELTQKGRMPLIRPPVREALGGAMQIDAATRRNLELTQALSGGREGSLLAAIDRSVTAGGARLLERRISAPSRDLDEIHARQAAVAHLVDEPRLTADLREALSRAPDMDRALSRLALERGGPRDLAAIRAGLTQGAAIAAMLGNDEIAVLAEAAHDLTGHDALIDLLDEALVAEPPLLARDGGFVAPGYDEDLDETRRLRDEGRGVIARMQADYIAETGVQSLKIKHNNVLGYFIETTSTHAERMLAPPLNERFIHRQTTANQIRFTTVELSELETRILNARDRALEIEREIFARLSRAVLDRAGPVGQAARALAEIDLTAAFADLASGEGWVRPEVDASRAFVIEGGRHPVVERALKRKGEAFVANDCALTQGETPAIWLLTGPNMAGKSTFLRQNALIAILAQAGGFVPARRAHIGLVSQLFSRVGAADDLARGRSTFMVEMVETAAILNQADDHALVILDEIGRGTATWDGLSIAWAVMEHLHATNRCRALFATHYHEMTSLSARLPGVENATVAVREWEGEVIFLHEVRKGAADRSYGVQVARLAGLPPSVVDRARDILHQLESGERQGTGKPAALLDDLPLFRAAPAPAPAGKAKPSVVEDRLRSLNPDTISAREALDLVYELRGMLDGEP
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: CYB_CHRSB
Sequence: MTNIRKTHPLIKIINHSFIDLPAPSNISSWWNFGSLLGLCLMIQIMTGLFLAMHYTADTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFIHVGRGMYYGSYTFMETWNIGVLLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVIVHLLFLHETGSNNPTGLNSDADKIPFHPYYTIKDLLGVLMLILFLMMLVLFFPDLLGDPDNYMPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALIMSILILALLPFLHTSKQRSMMFRPITQALYWILVANLLVLTWIGGQPVEHPFIIIGQLASISYFSIILILMPISGIIEDKLLKWSL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SLX1_CAEBR
Sequence: METFILSSDSDDDCPPPPKRRSIEGVPKSFDGDKKMRFSFDVTRDIILEDSEAPCSSNNIFTPSFRRDSNKTLLKTPVSLRRRSRSMNCMTPIVDTINEPPINQVCSAFVQKEIQLDDDDDDEKESSTEHADDDLNLRALLSPEKKKRKEKVDKRRPFGVEEVQNEFYGVYCLISRSERQCYKNRCYIGYTVDPNRRIMQHNGGRFKGGAKKTDSRGPWDMVCVVHGFPNHVAALRFEWAWQNPAVSKSLKEKQLKKERKETPFAYQLRIACELMNSEAFSRFALTFRWLNTKEELPFPISCTPPNHVKLRYGKVKKEMSLVPAKSADYVAMGECRLCGKDIEKLWGLVRCISQSCHSHFHSKCLAEHGLKNKNEYADQIYPLKSNCPICGHFYLWGDVVREQRRIIKVSTKCAEEFRNKVVRKDLPHREISSRLRLKK
What is the function of this protein?
Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA (Potential).  Has a preference for replication forks over 5' flap structures or Holliday junctions and shows much lower activity toward 3' flap structures (By similarity).  Required for proper crossover distribution through inhibition of crossover formation at the central region of chromosomes (By similarity).
What are the official names of this protein?
Structure-specific endonuclease subunit SLX1 homolog, GIY-YIG domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the SLX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DAPB_RIPO1
Sequence: MTTDSLIPVVVNGAAGKMGREVVKAVAQAEDMMLVGAVDYNPNYRGQDVGEVAGCGALEVPIVDDLQSILVLATQEKIQGVMVDFTHPDSVYENVRSAIAYGVRPVVGTTGLTEEQLKDLADFADKASTGCLVIPNFSIGMVLLQQAAVQASQYFDHVEIIELHHNQKADAPSGTAIKTAQMLSGLGKTYNPPMVKETETIAGAKGALVDDNIRIHSVRLPGLIAHQEVIFGAKGEIYTLRHDTSDRSCYMAGVLLSIRKVTQLQSLVYGLEKIL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEXT_TALMI
Sequence: MATMLKLLALTLAISESAIGAVMHPPGNSHPGTHMGTTNNTHCGADFCTWWHDSGEINTQTPVQPGNVRQSHKYSVQVSLAGTNNFHDSFVYESIPRNGNGRIYAPTDPPNSNTLDSSVDDGISIEPSIGLNMAWSQFEYSHDVDVKILATDGSSLGSPSDVVIRPVSISYAISQSDDGGIVIRVPADANGRKFSVEFKTDLYTFLSDGNEYVTSGGSVVGVEPTNALVIFASPFLPSGMIPHMTPDNTQTMTPGPINNGDWGAKSILYFPPGVYWMNQDQSGNSGKLGSNHIRLNSNTYWVYLAPGAYVKGAIEYFTKQNFYATGHGILSGENYVYQANAGDNYIAVKSDSTSLRMWWHNNLGGGQTWYCVGPTINAPPFNTMDFNGNSGISSQISDYKQVGAFFFQTDGPEIYPNSVVHDVFWHVNDDAIKIYYSGASVSRATIWKCHNDPIIQMGWTSRDISGVTIDTLNVIHTRYIKSETVVPSAIIGASPFYASGMSPDSRKSISMTVSNVVCEGLCPSLFRITPLQNYKNFVVKNVAFPDGLQTNSIGTGESIIPAASGLTMGLNISNWTVGGQKVTMENFQANSLGQFNIDGSYWGEWQIS
What are the official names of this protein?
Dextranase, Alpha-1,6-glucan-6-glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 49 family.
What are the subcellular locations of this protein?
Secreted.
Protein: VATA_SULIY
Sequence: MNNGRIVRINGPLVVADNMKNAQMYEVVEVGEPRLIGEITRIEGDRAFIQVYEDTSGIKPNEPVYRTGAPLSIELGPGLIGKIFDGLQRPLDSIKELTKSPFIARGIKVPSVDRKTKWHFIPKVKKGDKIEGGDIIGIVNETPLVEHRILVPPYVHGTLKEIVAEGDYTVEDPIAVVDMNGDEAPIRLMQRWPVRIPRPFREKLEPTEPLLTGTRVLDTIFPIAKGGTAAIPGPFGSGKTVTLQSLAKWSAAKIVIYVGCGERGNEMTDELRQFPSLKDPWTGRPLLERTILVANTSNMPVAAREASIYVGITMAEYFRDQGYDTLLVADSTSRWAEALRDLGGRMEEMPAEEGFPSYLPSRLAEYYERAGRVKTVGKPERFGSVTVASAVSPPGGDFTEPVTSQTLRFVKVFWPLDVSLAQARHYPAINWLQGFSAYVDLVANWWNTNVDPKWREMRDMMVRTLIREDELRQIVRLVGPESLAEKDKLVLETARLIKEAFLKQNAYDDIDAFSSPQKQARVMRLIYLFNTHASRLVERGIPTKKIVDSMGQLLPEIIRSKAAIKNDELNKYDELERKLINVFENLEKEAGT
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: LHX1_RAT
Sequence: MVHCAGCKRPILDRFLLNVLDRAWHVKCVQCCECKCNLTEKCFSREGKLYCKNDFFRCFGTKCAGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYLSNSSVAKENSLHSATTGSDPSLSPDSQDPSQDDAKDSESANVSDKEGGSNENDDQNLGAKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLVDRLEPGELIPNGPFSFYGDYQSEYYGPGGNYDFFPQGPPSSQAQTPVDLPFVPSSGPSGTPLGGLDHPLPGHHPSSEAQRFTDILAHPPGDSPSPEPSLPGPLHSMSAEVFGPSPPFSSLSVNGGASYGNHLSHPPEMNEAAVW
What is the function of this protein?
Potential transcription factor.  May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity).
What are the official names of this protein?
LIM/homeobox protein Lhx1, LIM homeobox protein 1, Homeobox protein Lim-1, Rlim.
What are the subcellular locations of this protein?
Nucleus.
Protein: FUCM_SHISS
Sequence: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
What is the function of this protein?
Involved in the anomeric conversion of L-fucose.
What are the official names of this protein?
L-fucose mutarotase, Fucose 1-epimerase, Type-2 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. FucU mutarotase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_CROS5
Sequence: MAVPKKKTSNAKRDQRKAHWKRTAALEAQKALSLGKSVLSGRSNSFVYPQDEEEDDEE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: KITH_BACFR
Sequence: MVLFSEDHIQETRRRGRIEVICGSMFSGKTEELIRRMKRAKFARQRVEIFKPAIDTRYSEGDVVSHDSNSISSTPIDSSASILLFTSEIDVVGIDEAQFFDSGLIDVCNQLANNGVRVIIAGLDMDFKGVPFGPMPALCAIADEVSKVHAICVKCGQLASFSHRTVKNDKQVLLGETAQYEPLCRECYQRALQEDREKS
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_BLOFL
Sequence: MQCIKCIEINLLQKKLGYFFHTVDLLLRALTHRSFSNKHNERLEFLGDSILNYSITNILYHRYNHMDEGDMSRIRSSLVCSRTLVELAKEFKLGNCLKLGQGELKNKGYNRESILADTVEAIIGGIFLDSNIKTIEMLIAFWYQFRLNKIDLEDKQKDPKTRLQEYLQHHHLPLPIYCINQVQGQAHDQIFIMNCQVSSLKYSVMGRGSSRRKAEQDAAENALKFLIEINND
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAL2_SALCH
Sequence: MNQLDGIKQFTTVVADSGDIESIRHYQPQDATTNPSLLLKAAGLEQYGHLIEDAIAWGKKHGGTQEQQVAAASDKLAVNFGAEILKSIPGRVSTEVDARLSFDKEKSIEKARHLVDLYQQQDVDKSRILIKLAATWEGIRAAEQLEKEGINCNLTLLFSFAQARACAEAGVYLISPFVGRIYDWYQARSPLEPYVVEEDPGVKSVRNIYDYFKQHRYETIVMGASFRRTEQILALTGCDRLTISPNLLKELKEKEEPVIRKLVPSSQMFHRPTPMTEAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase 2.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTB1_PSE14
Sequence: MNNLSLANEKTKIQVRGLEFFYNNQKSLKSIDMTIPEKRITAIIGPSGCGKSTLLRVFNRIYAMYPKQEARGEVLLNGENILAPGYSMNRLRSHVGMVFQKPVPFPMSIFDNISYAIKHHEKLSRREMEDRVEQALRGAALWDEVKDKLKQSATGLSGGQQQRLCIARTIALRPQVLLLDEPTSALDPISTGRIEQLITELKEQFTVIIVTHNMQQAARCSDYTAFMFMGELIEHGDTDTIFTKPSKTQTEDYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 1, ABC phosphate transporter 1, Phosphate-transporting ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DCDA_THEAC
Sequence: MGIYDIFDDESARSISGMSIDEMAKKYGTPVIIYSRARIVSNIRRIREAYENRVRMLYSVKANDNPRIIEIMHQESIGSDSASPMEIMMSIFSGIPPEDILYSPNNASEYDLNFALDRGIAINFNTFTQYRKMREKPERISFRINPGFGMGEFAGTTTGGARTKFGIDPDAAILAYRKAREDGIREFGIHMMIGSNNRDHVKIAEAYSNFFRIADRIGREAGVSFQFADVGGGLGIPYVQGENELDIAALGSAVLKEFDRYHFGDLVLEPGRYLVGDAGIIVGTVNDVHNGFAGTDIGMNLNIRPALYGARHTIIPVGERVEGEKITVTGQICENTDRIGDTAWRLSEGDRIMVLDAGAYVYSMSSRYNGRPRPPEIMIMEDGKDVMIRRREDFSDFIATVV
What is the function of this protein?
Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.
What are the official names of this protein?
Diaminopimelate decarboxylase, DAP decarboxylase, DAPDC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
Protein: RIBX_NOSP7
Sequence: MTIYFYKVWQPYGCFSNFSPHGIHIQDTYWATVEHYYQAQKFVGSKDAAIIPLIHAAATPEEAAALGRCSTRQLRRDWDLVKTQIMREAVLKKFLTHADIREVLLKTGDELLVENSPTDSFWGCGANKAGLNHLGKTLMSVREEIRNLLSLTGIYE
What is the function of this protein?
Catalyzes the hydrolysis of the N-glycosidic bond in the first two intermediates of riboflavin biosynthesis, which are highly reactive metabolites, yielding relatively innocuous products.  Thus, can divert a surplus of harmful intermediates into relatively harmless products and pre-empt the damage these intermediates would otherwise do.  May act on other substrates in vivo.  Has no activity against GTP, nucleoside monophosphates or ADP-ribose.
What are the official names of this protein?
N-glycosidase Npun_R5314, Riboflavin biosynthesis intermediates N-glycosidase.
What is the protein family that this protein belongs to?
Belongs to the YbiA family.
Protein: GLYA_CHLL2
Sequence: MDTDILRMQDKEVFEAIAGETLRQTETLELIASENFTSRAVMQACGSLMTNKYAEGYPGKRYYGGCEFVDIAENLARDRAKKLFGCQYVNVQPHSGSSANMAVLFSVLKPGDRIMGLDLSHGGHLTHGSPVNFSGQLFDAHSYGVDRETGCIDMNRVEELALEVRPKLIICGASAYSQGFDFKAFREIADKVGALLMADIAHPAGLIAAGLLSDPMPHCHFVTTTTHKTLRGPRGGMIMMGSDFENPLGITIKTKTGSRVKMMSEVMDAEVMPGIQGGPLMHIIAGKAVAFGEALQPAFREYAVQVRKNAAAMAESFAGLGYNIVSGGTKNHLMLLDLRNKEVNGKVAENLLHEAGITVNKNMVPFDDKSPFVTSGIRIGTAAMTTRGMTENDSRTVAGLIDQVISSANSAGVEEICRTVRHDIRELCLAYPLEGYGVNP
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_CAMHC
Sequence: MKKNVKKVVLAYSGGLDTSVILKWLEDNYKCEVVTFTADIGQNEDLKPIKEKALKLGIKKENIFIKDLREEFVRDYVFPMFRANAVYEGEYLLGTSIARPLISKYLVEIAKKTNADAIAHGATGKGNDQVRFELGAYALNPNIKVIAPWREWDLNSREKLLAYAEKNGIDIAKKKGKSPYSMDANLLHISYEGLVLEDPNHAPEADMWRWTTDPKLAPNESEIIEIEYKNGNPIALNGKNLKPHEMLNELNNLGAKHGIGRLDIVENRFVGMKSRGCYETPGGTIMLKAHRAIESITIDKGAAHLKDELMPKYAELIYNGFWFSPERSMLQALIDKSQEYVNGKVKLELYKGNVIVIGRESKSDTLFNVNFSTFEEDSVYNQKDAEGFIKLNALRFIIAGKNGRKI
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLD_RICTY
Sequence: MNNTVLILKKISKHYKQGNTIVKVLDDLNLTANEGELIAIIGSSGSGKSTLLHIAGLLDKPTNGQVIIPNSKYKKYHLIRLYYLGFIYQQHHLLKDFTALENVIIPRLIRGLDQKEAIRDATKILDDLGLEKKLYNMPGELSGGEQQRVAIARSLINKPRIILADEPTGNLDPKSTNEVFNLFLKVAQKQNTTVIMVTHNHELAHKMDKLYNLKNGLLNIA
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CED11_CAEEL
Sequence: MDETDPVPDMSLLPDTVPVVVSGDGSAAGIQLCPALILGSPQALPGAIKHIYSRLAAAASEVDQGVPDLIISLISHGNSLSTKYMSSVENGLKSFLIGCGTWLISSGEVNDPMSRVASGALKNVLPQLEHQAEVLHILVNSDDMIASDTTNSKSVVDTSLNTLLLICRKEPNDSYETVASSIAKLRAATAVKLAHPPPALLIGVPSEPMSPSTYGNSAAILLSPSNDKRPFPVAIFAGASKESLIELLFFVEHGIPVIILQDSCELCAILHSSHLLLETSNFDNDKFISWLRSQLYPLGLADCYTLITKLLVSSNSGDVQLIEFIDSSQLSELSSVVVDRCLECYATTGEERQVLLLAAKLNSPSVLSSMDVAAQLDEELLTMILCECITKDDQLHFLSSVLQLSPPIRVTSNMLIRMMHHADEHFFTTIVLCQCMGYSYIPSEIDPRFANDIQKLVKKLSFGVDNLFDPNVFCNDSSHRDKHESIRILAIWSLLLHRPGIVKCLAAFADEPVAFSMVLSRIARSLGHESHDWHFYEKSLNTLSDSLSGSATTLFDTVFSTSPAKAYQLLCQPMEYFYGFNMTQLAFHCNAREIIAHECCQRWVHRKLYGNLQAKNFPIFLPKWAKICISAVLIIPVKFWMLVRPRERTKQDTVSPTVALLDVGKFPQKQRAISTYSVISSRSEALTALTAPLSTAFGFNSALNGAESATPQSMVFPLNIEEIDKDPRPFGKKNRIRRAHAPTLSTFYSTPIVKYWLSLLFRIVFICCLAYSVVLPGCGSNLWDTGMWVWSFFWWIENCFVLTARARKIPLSLMPWRVFDVFAFFVFLILLLVMKVFPVTPVLEVLGIDSIYSAKVVSAFFVLYVSYSTLFTYIPLSDIFGPMIVRVKLMLLRDFTNFLFMIALVMLSSAVAIQAVVFPDRPVTMEVFRKTLSWIWLSLFTTDLSNLSESETCRKSFLGAPKRYCSSVGQYANPSCPSQSLPAYLIVIEYFVILKLLLWPILFAFFSKTAKNVDDEADKIWRFQLYSLAEDFRLRPPLPPPLTIFCLICSACCRFSNSFSGFFSDFDHPDFEARDKCRTTWKFGSIYRNPSVPFKRNEFVNSFWRKLSMEQWKNTQQKAKISANKSELQELHNIHNHIRMMTLRDSYENSGTRKASELQFFEKYPESNILKISVNMVSKPWTVLVPRYNPPFYCKPAEDFPSDVQKYVDIATEQNVGELKRIWRSRQANDVTSSNDKCWKLSAAGFPLNPNGRTGMAGRGNHPRFGANRRCYYVVLSGGVEAKCQVLVDSQKNIPNEWHLENSSKDEHLTSILKMIGISDSDAHMFSMRRLDSSIITADKRIPSNDTSPAHLASEVAENENDTDNAWTEHDVWAISLRERRIITTIIGYSWLPTSAIRGTVLPWQADLVFRAKTIYGL
What is the function of this protein?
Plays a major role in programmed cell death.
What are the official names of this protein?
Protein ced-11, Cell death protein 11.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HPNE_ZYMMO
Sequence: MSVTHIIGAGLAGLSAAVAITHAGGRVKIYEASAMAGGRARSYHDKKLGIEIDNGNHMLLSGNHSAKTYLKRIGAEHRFKSPKEAAFSFCDLSDKERFTIKLSNGPLPWWVLCAKSRVPHSKAKDYLALLSLLLADHNTKIGDLVPDNTALWRKLLDPFFVSVLNTPAREGAACLAAAVIRETLMKGGKACIPRIAYPNLASSFIDPALDYLKARGVEVDFRNRLRQIHFSGQDVASLEFAHQDVKLGKGDKVIIALPAWVVQSLIPDIETPDKYQAIINAHFLMKPTAAMPHIMGVVGGTADWIFTFENRISVTISAANHLLALEKEELVKRIWDDIQTVYAFKQDMPEWQVVTEKRATFEATVEQNNRRPPAVTAWNNLFLAGNWVRTGLPATIESAIRSGQTAADLALSHS
What is the function of this protein?
Involved in the biosynthesis of the hopanoid precursor squalene (SQ) from farnesyl diphosphate (FPP).  Catalyzes the third (last) step, the reduction of hydroxysqualene (HSQ) to SQ.
What are the official names of this protein?
Hydroxysqualene dehydroxylase, SQase.
What is the protein family that this protein belongs to?
Belongs to the HpnE family.
Protein: RS11_PSEA7
Sequence: MAKPAARPRKKVKKTVVDGIAHIHASFNNTIVTITDRQGNALSWATSGGSGFRGSRKSTPFAAQVAAERAGQAALEYGLKNLDVNVKGPGPGRESAVRALNACGYKIASITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: UPPP_YERP3
Sequence: MTDMYSLFVAFILGVVEGLTEFLPVSSTGHMIIVGELLGFTGDKAKTFEVIIQLGSILAVVVVFWRRLFGLIGIHFGAVPHEGKTNGHLTLGHILLAMIPAVILGLAFHDVIKALFDPKSVMYALVAGGVLLLAAEWLKPKNPKAVGLDDITYRQAFAIGCFQCLALWPGFSRSGATISGGMLVGVNRYAASEFSFILAVPMMIGASGLDLYKSLHFLTLGDLPMFAVGFITAFIVALIAIKTFLSLIKRISFVPFAIYRFIVAAVVYWVFM
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PAHO_EQUPR
Sequence: APMEPVYPGDNATPEQMAQYAAELRRYINMLTRPRY
What is the function of this protein?
Hormone secreted by pancreatic cells that acts as a regulator of pancreatic and gastrointestinal functions probably by signaling through the G protein-coupled receptor NPY4R2.
What are the official names of this protein?
Pancreatic polypeptide, PP.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.