PharMolix/UniProtQA huggingface dataset:
Protein: DNLJ_SHIF8
Sequence: MESIEQQLTELRTTLCHHEYLYHVMDAPEIPDAEYDRLMRELRELETKHPELITPDSPTQRVGAAPLAAFSQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKNNEKVTWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLHGENIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGVLEGGELPDTHLGRLLQFKKWGVPVSDRVTLCESAEEVLAFYHKVEEDRPTLGFDIDGVVIKVNSLEQQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVHVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEDTREVVFPTHCPVCGSDVERVEGEAVARCTGGLICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEKEYVHTPADLFKLTAGKLTGLERMGPKLAQNVVNALEKAKETTFARFLYALGIREVGEATAAGLAAYFGTLEALEAASIEELQKVPDVGIVVASHVHNFFAEESNRNVISELLAEGVHWPAPIVINAEEIDSPFAGKTVVLTGSLSQMSRDDAKARLVELGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVIDEAEMLRLLGS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: NPL4_DICDI
Sequence: MIIAVRSPSGTTKINVSDTAIVKDLYVKLKENNVDIDGKSITKTPRDPPLEVGDKLSSLGIKSGDLLHLVGNNNNNNNDNKASSGSNNNNNNNNISKKEISYDEKLPNGLTPRCKHAVGDKCVFCSDAQGMKRCDHPENATCPNCQNKKFKGKRLKWLCNHPAGGKCSNCLRVGKNVSYKCNHGSTATCVNCMDKDDEDQDDNEEDNKDNKDNSEIKKSGFVPKVAIKNEVKTKCLHGPNQKCINCLPKDDPNSIEVPKRRCKNHGINGSCVECIEWRESLKMRLKSQDNPHAPGALVDFQSANIFQQYIANSKYEQQRIGFLFGNFLSDGSVVVDSIYEPPQECKDKQTPTLLPDPLADKIESMASMLGLTRVGWIFSHPSRKYTMSSTEIIQAASYQNKYGPSFVTLILSVNSDGQSNMEAFQVSDQALKLEKTGEFLPTQPDPTKCKLKSPVFEEGTETINADTHFFIVTVPLKAREDKSIFNISFPVENRIPVNTLSDLASYKLEHKDVSPLKFFSDFHFLIFLLENQFLDFQSDFPIICENIRSRSSENLIGYLEIINYQIGDIIGHDQFN
What is the function of this protein?
May be part of a complex that binds ubiquitinated proteins and that is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome.
What are the official names of this protein?
Nuclear protein localization protein 4 homolog.
What is the protein family that this protein belongs to?
Belongs to the NPL4 family.
Protein: RL36A_SCHPO
Sequence: MAPGLVVGLNKGKVLTKRQLPERPSRRKGQLSKRTSFVRSIVREVAGFAPYERRVMELIRNSQDKRARKLAKKRLGTLKRAKGKIEELTSVIQSSRLAH
What are the official names of this protein?
60S ribosomal protein L36-A.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL36 family.
Protein: ALS3_CANAX
Sequence: MLQQYTLLLIYLSVATAKTITGVFNSFNSLTWSNAATYNYKGPGTPTWNAVLGWSLDGTSASPGDTFTLNMPCVFKFTTSQTSVDLTAHGVKYATCQFQAGEEFMTFSTLTCTVSNTLTPSIKALGTVTLPLAFNVGGTGSSVDLEDSKCFTAGTNTVTFNDGGKKISINVDFERSNVDPKGYLTDSRVIPSLNKVSTLFVAPQCANGYTSGTMGFANTYGDVQIDCSNIHVGITKGLNDWNYPVSSESFSYTKTCSSNGIFITYKNVPAGYRPFVDAYISATDVNSYTLSYANEYTCAGGYWQRAPFTLRWTGYRNSDAGSNGIVIVATTRTVTDSTTAVTTLPFDPNRDKTKTIEILKPIPTTTITTSYVGVTTSYSTKTAPIGETATVIVDIPYHTTTTVTSKWTGTITSTTTHTNPTDSIDTVIVQVPSPNPTVTTTEYWSQSFATTTTITGPPGNTDTVLIREPPNHTVTTTEYWSESYTTTSTFTAPPGGTDSVIIKEPPNPTVTTTEYWSESYTTTSTFTAPPGGTDSVIIKEPPNHTVTTTEYWSQSYTTTTTVTAPPGGTDTVLVREPPNHTVTTTEYWSQSYTTTTTVIAPPGGTDSVIIREPPNPTVTTTEYWSQSYATTTTITAPPGETDTVLIREPPNHTVTTTEYWSQSYATTTTITAPPGETDTVLIREPPNHTVTTTEYWSQSFATTTTVTAPPGGTDTVIIREPPNHTVTTTEYWSQSYATTTTITAPPGETDTVLIREPPNHTVTTTEYWSQSYATTTTIIAPPGETDTVLIREPPNPTVTTTEYWSQSYTTATTVTAPPGGTDTVIIYDTMSSSEISSFSRPHYTNHTTLWSTTWVIETKTITETSCEGDKGCSWVSVSTRIVTIPNNIETPMVTNTVDSTTTESTSQSPSGIFSESGVSVETESSTVTTAQTNPSVPTTESEVVFTTKGNNENGPYESPSTNVKSSMDENSEFTTSTAASTSTDIENETIATTGSVEASSPIISSSADETTTVTTTAESTSVIEQPTNNNGGGKAPSATSSPSTTTTANNDSVITGTTSTNQSQSQSQYNSDTQQTTLSQQMTSSLVSLHMLTTFDGSGSVIQHSTWLCGLITLLSLFI
What is the function of this protein?
Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation.  Plays an important role in the biofilm formation and pathogenesis of C. albicans infections.  Necessary for C. albicans to bind to N-cadherin on endothelial cells and E-cadherin on oral epithelial cells and subsequent endocytosis by these cells.  During disseminated infection, mediates initial trafficking to the brain and renal cortex and contributes to fungal persistence in the kidneys.
What are the official names of this protein?
Agglutinin-like protein 3, 3D9 antigen, Adhesin 3.
What is the protein family that this protein belongs to?
Belongs to the ALS family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Secreted, cell wall. Note=Covers the surface of the germ tube.
Protein: SURE_RHOPB
Sequence: MRILCTNDDGIHAPGLKIVEQIARQLSDDVWVVAPELDQSGVSHSLSLNDPLRLREIGPRHFAVRGTPTDCVIMGARHILGDKGPDLVLSGVNKGRNVAEDVVYSGTIAGALEGSILGFPSFALSQEFSMDNKGTPLWETALAHGPAILRKIIDQGVPKNTVININFPACAPGDVVGVRVTRQGKRNQGFLRVDERRDGRGNPYFWIGFERIAVVDTPAEGTDLAALAAGYVSVTPLRLDRTDDVFSQVLNTTLG
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPOL_VACCW
Sequence: MDVRCINWFESHGENRFLYLKSRCRNGETVFIRFPHYFYYVVTDEIYQSLSPPPFNARPLGKMRTIDIDETISYNLDIKDRKCSVADMWLIEEPKKRSIQNATMDEFLNISWFYISNGISPDGCYSLDEQYLTKINNGCYHCDDPRNCFAKKIPRFDIPRSYLFLDIECHFDKKFPSVFINPISHTSYCYIDLSGKRLLFTLINEEMLTEQEIQEAVDRGCLRIQSLMEMDYERELVLCSEIVLLRIAKQLLELTFDYVVTFNGHNFDLRYITNRLELLTGEKIIFRSPDKKEAVYLCIYERNQSSHKGVGGMANTTFHVNNNNGTIFFDLYSFIQKSEKLDSYKLDSISKNAFSCMGKVLNRGVREMTFIGDDTTDAKGKAAAFAKVLTTGNYVTVDEDIICKVIRKDIWENGFKVVLLCPTLPNDTYKLSFGKDDVDLAQMYKDYNLNIALDMARYCIHDACLCQYLWEYYGVETKTDAGASTYVLPQSMVFEYRASTVIKGPLLKLLLETKTILVRSETKQKFPYEGGKVFAPKQKMFSNNVLIFDYNSLYPNVCIFGNLSPETLVGVVVSTNRLEEEINNQLLLQKYPPPRYITVHCEPRLPNLISEIAIFDRSIEGTIPRLLRTFLAERARYKKMLKQATSSTEKAIYDSMQYTYKIVANSVYGLMGFRNSALYSYASAKSCTSIGRRMILYLESVLNGAELSNGMLRFANPLSNPFYMDDRDINPIVKTSLPIDYRFRFRSVYGDTDSVFTEIDSQDVDKSIEIAKELERLINNRVLFNNFKIEFEAVYKNLIMQSKKKYTTMKYSASSNSKSVPERINKGTSETRRDVSKFHKNMIKTYKTRLSEMLSEGRMNSNQVCIDILRSLETDLRSEFDSRSSPLELFMLSRMHHSNYKSADNPNMYLVTEYNKNNPETIELGERYYFAYICPANVPWTKKLVNIKTYETIIDRSFKLGSDQRIFYEVYFKRLTSEIVNLLDNKVLCISFFERMFGSKPTFYEA
What is the function of this protein?
Catalyzes DNA synthesis.  Acquires processivity by associating with a heterodimeric processivity factor comprised of the viral OPG148/A20 and OPG116/D4 proteins, thereby forming the DNA polymerase holoenzyme.  Displays 3'- to 5' exonuclease activity.  Might participate in viral DNA recombination.  Does not perform OPG116/D4synthesis across an abasic site.
What are the official names of this protein?
DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
Protein: ATPG_RICCN
Sequence: MSNLKQLRTRIKSVKSTQKITKAMQLVSASKMAKIKSQIANSNFYIEAVSKMMSAILSIDMYELSIEEQKFFNTVPNKANLLIVMTSQRGLCGTFNYSIIKQVKNDIKELENKGEQIKLIIIGKKGYEALKRQYVNYIDSYFELPKIHDENLMLQVKQKIMSAVENLEVSNCVIYFNKFKNAMTQIMTRQQILPVAKYQDDSMIDNPIVNLVGFGYKERGVKPINNRRATSDIVGESKSIDYNYEYEGESLISNLINLYVNSQINYALLQSRASEEGARMTAMENATNNANDLISKLVLKLNRSRQAIITTELIEIIAGSEVV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ETF2_MYXVL
Sequence: MRYVVNPQLVLYVEKGQKIKRALYLTPYGTLDDKSPIYYFLSTHLKITDPEVHKRHILLTLKISQLKGYLCDLLRIRNDVIIYSHKNNLEYSYVDNTIFNPFAHTQKKTLIKSDGFLYNIYPDACDFLVIWVADAEDTSIAEFGSYEDVDVNILKFETRLLEVFDDLDLDMTIESKFNNIFRTNLKFTGLRKLIKKINEFNGSRYKSLLYKSDEYFINLTGNKFILTDERLNLTVWDSDGVVTFSSDGDTIMINNVKLFTSLLTDIDLQMERIKGDVTYKIFLSTPITSRIKLNIETSFIFVETATNNILLSADKRISIILAKNHISIKVKNYIPNIEKYFTFLVIAINSMFNNIQQASDFTKVETVYWSRICQNTKNKHRKPVIVSSLDEDMEKVSDNFYKSSTKEVFINSSGIMFSCLDPLNKYNYVGFLSIFYRLQKMCIPCCFLKNQSHTETFSSCVYQKEIASDVINPYILNFGKVVTKSKISFLPIIFDSFFNEGVKIIFEQDNKRLKETIGYHVIKSCDEDIKRLRTISDIIAFVNEDKNILIAEDIIYFPMNYVDIGTRVYILIQEIVHEIVVVKKHMSKDAIEVFPPNYKLVKNLFPRQTKFITIRSDSGMELTTDGFLVDGKEFNVDLSSNYVAFTKNITTPYTLSKYFSPLFKYAITESKNRFMKTWLINTMLRLGIDLDLDTNILPKLEKYYPNHGKSV
What is the function of this protein?
Acts with RNA polymerase to initiate transcription from early gene promoters.  Is recruited by the RPO-associated protein of 94 kDa (RAP94) to form the early transcription complex, which also contains the core RNA polymerase.  ETF heterodimer binds to early gene promoters (By similarity).
What are the official names of this protein?
Early transcription factor 82 kDa subunit, ETF large subunit.
What is the protein family that this protein belongs to?
Belongs to the poxviridae VETF large subunit family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).
Protein: RBL_EPASP
Sequence: VGFKAGVKDYKLTYYTPNYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVPGDENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPAAYAKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMMKRAVFARELGVPIVMHDYLTGGFTANTSLAEYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHAGTVVGKLEGEREITLGFVDLLRDDYIEKDRGRGIYFSQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREAGQWSNELSAACAIWKEIKFEFPAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CSPA_STAHJ
Sequence: MKQGTVKWFNAEKGFGFIEVEGENDVFVHFSAINQDGYKSLEEGQSVEFEVVEGDRGPQAANVVKL
What is the function of this protein?
Involved in cold stress response.
What are the official names of this protein?
Cold shock protein CspA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROQ1_PSEAE
Sequence: MATLLVLHGPNLNLLGTREPGTYGSTTLGQINQDLERRAREAGHHLLHLQSNAEYELIDRIHAARDEGVDFIIINPAAFTHTSVALRDALLAVSIPFIEVHLSNVHKREPFRHHSYFSDVAVGVICGLGATGYRLALESALEQLQRP
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase 1, 3-dehydroquinase 1, Type II DHQase 1.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: MOLC_HAEIN
Sequence: MNKALSVENLGFYYQAENFLFQQLNFDLNKGDILAVLGQNGCGKSTLLDLLLGIHRPIQGKIEVYQSIGFVPQFFSSPFAYSVLDIVLMGRSTHINTFAKPKSHDYQVAMQALDYLNLTHLAKREFTSLSGGQRQLILIARAIASECKLILLDEPTSALDLANQDIVLSLLIDLAQSQNMTVVFTTHQPNQVVAIANKTLLLNKQNFKFGETRNILTSENLTALFHLPMFEQQAQYKESFFTHFVPLYKTLLK
What is the function of this protein?
Part of the ABC transporter complex MolBCA involved in molybdate import (PubMed:22078568, PubMed:24722984).  Responsible for energy coupling to the transport system (PubMed:24722984).  Functions as a low-affinity molybdate transporter (PubMed:24722984).
What are the official names of this protein?
Molybdate import ATP-binding protein MolC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DPOL_HHV2H
Sequence: MFCAAGGPASPGGKPAARAASGFFAPHNPRGATQTAPPPCRRQNFYNPHLAQTGTQPKALGPAQRHTYYSECDEFRFIAPRSLDEDAPAEQRTGVHDGRLRRAPKVYCGGDERDVLRVGPEGFWPRRLRLWGGADHAPEGFDPTVTVFHVYDILEHVEHAYSMRAAQLHERFMDAITPAGTVITLLGLTPEGHRVAVHVYGTRQYFYMNKAEVDRHLQCRAPRDLCERLAAALRESPGASFRGISADHFEAEVVERADVYYYETRPTLYYRVFVRSGRALAYLCDNFCPAIRKYEGGVDATTRFILDNPGFVTFGWYRLKPGRGNAPAQPRPPTAFGTSSDVEFNCTADNLAVEGAMCDLPAYKLMCFDIECKAGGEDELAFPVAERPEDLVIQISCLLYDLSTTALEHILLFSLGSCDLPESHLSDLASRGLPAPVVLEFDSEFEMLLAFMTFVKQYGPEFVTGYNIINFDWPFVLTKLTEIYKVPLDGYGRMNGRGVFRVWDIGQSHFQKRSKIKVNGMVNIDMYGIITDKVKLSSYKLNAVAEAVLKDKKKDLSYRDIPAYYASGPAQRGVIGEYCVQDSLLVGQLFFKFLPHLELSAVARLAGINITRTIYDGQQIRVFTCLLRLAGQKGFILPDTQGRFRGLDKEAPKRPAVPRGEGERPGDGNGDEDKDDDEDGDEDGDEREEVARETGGRHVGYQGARVLDPTSGFHVDPVVVFDFASLYPSIIQAHNLCFSTLSLRPEAVAHLEADRDYLEIEVGGRRLFFVKAHVRESLLSILLRDWLAMRKQIRSRIPQSTPEEAVLLDKQQAAIKVVCNSVYGFTGVQHGLLPCLHVAATVTTIGREMLLATRAYVHARWAEFDQLLADFPEAAGMRAPGPYSMRIIYGDTDSIFVLCRGLTAAGLVAMGDKMASHISRALFLPPIKLECEKTFTKLLLIAKKKYIGVICGGKMLIKGVDLVRKNNCAFINRTSRALVDLLFYDDTVSGAAAALAERPAEEWLARPLPEGLQAFGAVLVDAHRRITDPERDIQDFVLTAELSRHPRAYTNKRLAHLTVYYKLMARRAQVPSIKDRIPYVIVAQTREVEETVARLAALRELDAAAPGDEPAPPAALPSPAKRPRETPSHADPPGGASKPRKLLVSELAEDPGYAIARGVPLNTDYYFSHLLGAACVTFKALFGNNAKITESLLKRFIPETWHPPDDVAARLRAAGFGPAGAGATAEETRRMLHRAFDTLA
What is the function of this protein?
Replicates viral genomic DNA.  The replication complex is composed of six viral proteins: the DNA polymerase, processivity factor, primase, primase-associated factor, helicase, and ssDNA-binding protein.  Additionally, the polymerase contains an intrinsic ribonuclease H (RNase H) activity that specifically degrades RNA/DNA heteroduplexes or duplex DNA substrates in the 5' to 3' direction.  Therefore, it can catalyze the excision of the RNA primers that initiate the synthesis of Okazaki fragments at a replication fork during viral DNA replication (By similarity).
What are the official names of this protein?
DNA polymerase catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Host nucleus. Note=the protein is present at discrete sites in nuclei, called replication compartments where viral DNA replication occurs.
Protein: MYS9_DROME
Sequence: MLEDTQLVWVRDAAEGYIQGRITEIGAKEFEVTPTDRKYPKRTCHFDDIHSSCDGPQDHDDNCELMLLNEATFLDNLKTRYYKDKIYTYVANILIAVNPYREIKELYAPDTIKKYNGRSLGELPPHVFAIADKAIRDMRVYKLSQSIIVSGESGAGKTESTKYLLKYLCYSHDSAGPIETKILDANPVLEAFGNAKTTRNNNSSRFGKFIEVHYDAKCQVVGGYISHYLLEKSRICTQSAEERNYHVFYMLLAGAPQQLRDKLSLGKPDDYRYLSGCTQYFANAKTEQLIPGSQKSKNHQQKGPLKDPIIDDYQHFHNLDKALGRLGLSDTEKLGIYSLVAAVLHLGNIAFEEIPDDVRGGCQVSEASEQSLTITSGLLGVDQTELRTALVSRVMQSKGGGFKGTVIMVPLKIYEASNARDALAKAIYSRLFDRIVGLINQSIPFQASNFYIGVLDIAGFEYFTVNSFEQFCINYCNEKLQKFFNDNILKNEQELYKREGLNVPEITFTDNQDIIELIEAKSNGIFTLLDEESKLPKPSYSHFTAEVHKSWANHYRLGLPRSSRLKAHRTLRDEEGFLVRHFAGAVCYNTEQFIEKNNDALHASLEGLVQECDNPLLQTLFPSGSSTSVRGKLNFISVGSKFKTQLGELMEKLEQNGTNFIRCIKPNSKMIDRQFEGSLALAQLKCSGTISVLELMEHGYPSRVLFADLYSMYKSVLPPELVSLPARTFCEAMFQSLNLSAKDFKFGITKVFFRPGKFVEFDRIMRSDPENMLAIVAKVKKWLIRSRWVKSALGALCVIKLRNRIIYRNKCVLIAQRIARGFLARKQHRPRYQGIGKINKIRTNTLKTIEIASGLKMGREEIISGVNDIYRQIDDAIKKIKMNPRITQREMDSMYTVVMANMNKLTVDLNTKLKEQQQAEEQERLRKIQEALEAERAAKEAEEQRQREEIENKRLKAEMETRRKAAEAQRLRQEEEDRRAALALQEQLEKEAKDDAKYRQQLEQERRDHELALRLANESNGQVEDSPPVIRNGVNDASPMGPNKLIRSENVRAQQQALGKQKYDLSKWKYSELRDAINTSCDIELLEACRQEFHRRLKVYHAWKAKNRKRTTMDENERAPRSVMEAAFKQPPLVQPIQEIVTAQHRYFRIPFMRANAPDNTKRGLWYAHFDGQWIARQMELHADKPPILLVAGTDDMQMCELSLEETGLTRKRGAEILEHEFNREWERNGGKAYKNLGAAKPNGPAAAMQKQQ
What is the function of this protein?
Myosin is a protein that binds to actin and has ATPase activity that is activated by actin.  Together CLIP-190 and jar may coordinate the interaction between the actin and microtubule cytoskeleton.  May link endocytic vesicles to microtubules and may be involved in transport in the early embryo and in the dynamic process of dorsal closure.  It is believed that its function changes during the life cycle.
What are the official names of this protein?
Myosin heavy chain 95F, 95F MHC, Protein jaguar.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Microtubule-associated.
Protein: IPYR_HELPJ
Sequence: MNLDQLEVSHDADSLCVVIEISKHSNIKYELDKESGALMVDRVLYGAQNYPANYGFVPNTLGSDGDPVDALVLSDVAFQAGSVVKARLVGVLNMEDESGMDEKLLALPIDKIDPTHSYVKDIDDLSKHTLDKIKHFFETYKDLEPNKWVKVKGFENKESAIKVLEKAIKAYQG
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRPR1_METMA
Sequence: MMDPQIERKLIEIMRVIHESDKPIGARAIADELNNRGYDIGERAVRYHLRILDERGFTRKHGYAGRTLTDLGENEMNDALIGDRFGFVISRIEEMAFRTTYNPETDKGDVVVNISYFDKDDFETVIELISYTAHAGYMISPRVRIFEEDSLEMSLPPGKIGIATVCSVTFDGLLLKAGIPVEPAYGGILQIENKKPARFLDLISYSGTSIDPIKIFMNRTPTSVLEVLEKGEGKILANMRQINSSAYEMTGKILKKAEKVGLAGCITLGEIDEYLLGAPVETGKFGAAVVGGINGICALEETGIEIETNPISTMLDYQTMKEI
What is the function of this protein?
Plays a major role in nitrogen regulation.  Under nitrogen sufficiency, binds to the nifH and the glnk1 promoters, leading to repression of the transcription of the genes.
What are the official names of this protein?
Global nitrogen regulator NrpRI, Nitrogen regulatory protein R I.
What is the protein family that this protein belongs to?
Belongs to the NrpR family.
Protein: TTCA_COLP3
Sequence: MTEAQLTLPTTKLSPTQKTQFIKLEKKLRRNVGQAIAQYNMIEDGDKVMVCLSGGKDSYAMLSILMLLKESAPIHFDIIAVNLDQKQPGFPEHILPEYLDKLGIEYHIVEEDTYGIVKEKVPEGKTTCSLCSRLRRAVLYKAAKKIGATKIALGHHRDDMIETLMLNMFYGGKMKAMPAKLVSDNGEHVVIRPLAFCKESELIQYSELKHFPIIPCNLCGSQPNMQRQNIKRMLNDWHDQFPGRIESMFTAMQNVVPSHLCDSNLFDFKSINSTSGIINGGDTAFDEVAIEAPQDLSMKNQPNADQLLNVVEVK
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_STAAE
Sequence: MARSIKKGPFVDEHLMKKVEAQEGSEKKQVIKTWSRRSTIFPNFIGHTFAVYDGRKHVPVYVTEDMVGHKLGEFAPTRTFKGHVADDKKTRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: CYSG_PSYA2
Sequence: MNTFPLFFKLEDRKVLIVGGGDVALRKADLLSRAGACITVLAPSINHEIQALLSSSKHELIYEHYNKTYMTNSRVIIAATDDERLNHQIHADATALNIPVNVVDTPHLCDFIFPAIVDRNPIVIGISSNGKAPVLARLLRARLETLIPQGYGKLAKLAGEFRGDVKAKIPTLTGRRQFWERAFEGKVSQLMFAGNENEALAQLQADLDNTAASITAKDATDDNGLSTASTSAPAIANEFTAARNTMGEVYIVGAGPGDPELLTFKALRLMQQADIVYYDALVSPQVLDLCRRDADKVFVGKKRRNHAVAQLGINELLVNSAKEGRRVVRLKGGDPFIFGRGGEEIESLRAHNIPYQVVPGITAANAAASYAGIPLTHRDHSQSVRFVTGFLKAGAPNNNFKNFLDTDETVVFYMGLHSLPRLTEGLIDAGRSAETPIAIVSNASMPNQQVLTGTLASIVELQEKNQLPTPALLIMGDVVSLHHDLAWYNLHNQQHNQNTSETDNNWLRGGTATTPKSNAQFNAHQQAHALSMITNLATEDGDLEQLIIG
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: HEM1_DESVM
Sequence: MDQEIYLIGLNHRTASVEVRERFALTDCTVLEQGVVPTGDDISEVVILSTCNRVEIMAVGNGPGVPARVLDCWAAARGQKRSDLEPFVYVHKGIDAVRHLFSVASSLDSMVVGEPQILGQLKDAYRKAVGRNATRVVLNRLLHKAFSVAKRVRTETGVASSAVSISYAAVELAKRIFGEMSQYKAMLIGAGEMAELAATHLLNSGIREIMVANRTFERGLQLARQFKGEAVLFQDLSVRLAEADIIISSTGAHEPIIRARDIKDVLKRRKNRPMFFIDIAVPRDIDPDVNNLDNVYLYDIDDLKEVVEENMAQRRDEAAKARSIVEEEAGNFAKWLKSLDLQPTIVDLLRRSERIAQDELARTLKRLGPVDDATREALQAMLCAIVKKVNHEPITFLKRRFDEEEAGTRYIDITRRMFNLDCDDVPDDAHSDRKHTQQRDDA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: PRMA_STRPJ
Sequence: METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSLDYVGNVDRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTALAEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMSLFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPGMENIHVAAGDLLKGVEIEADVIVANILADILIHLIDDAYRLVKDEGYLIMSGIIKDKWDMVRESAESAGFFLETHMIQGEWNACVFKKTKDISGVIGG
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAP1_COCPS
Sequence: MKSLSLLALAAIAPPAAVAAVVDHQVPFENRPVQGLPEKFLIQLGPEQTRWVTEDEKWALKMEGVNFFDITAEPDRGFSVKSHERIQVSFPSEVKHQTELAPLLEQLSKDNMRQNLVHFTSFHTRYYKSETGVQSATWLFEQVEEAIQDSGAAQHAVKVERFEHSWGQFSIIATIPGRTNKTVVIGAHQDSINLFLPSILPAPGADDDGSGTVTILEAFRVLLQSEAVQQGNAANTIEFHWYSAEEAGLLGSQAIFSDYSKTGRDIKAMLQQDMTGYVEGTTKAGEVESVGVITDFVDPGLTEFIKRVITGYCTIPFVLTQCGYACSDHASASRYGYPSAFVIESEFKRSNQRIHTTGDTVDLLSFDHMLQHARMTLAFAYELAFAEL
What is the function of this protein?
Extracellular aminopeptidase that allows assimilation of proteinaceous substrates.
What are the official names of this protein?
Leucine aminopeptidase 1, Leucyl aminopeptidase 1, LAP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28E subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DOHH_NEOFI
Sequence: MSPSATDTTEGVDPTILTLRKVLTSESEPLARRFRALFSLKHLACLQPPTEKTLPAIQAIAAAFTSPSALLKHELAYCLGQTRNPESVPFLQQVAKDTEQDTMCRHEAAEALGALGYEDSLEILKALRDNQNESDVIRETCDIAVDRILWENSEARKAEKLKTSDFTSIDPAPPLPMTASEPSIPEIEKTLLDTSLPLFLRYRAMFALRDLASPPDLPTATRAVEALAKGLKDPSALFRHEIAFVFGQLCHPASIPSLTEALSNQSEAGMVRHEAAEALGSLGDCEGVEETLRKFLNDPEQVVRDSVIVALDMAEYEKNGEVEYALVPDAGVAAA
What is the function of this protein?
Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
What are the official names of this protein?
Deoxyhypusine hydroxylase, DOHH, Deoxyhypusine dioxygenase, Deoxyhypusine monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine hydroxylase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: H1S_STRPU
Sequence: PASPQKRAASPRRSPKKSPRKSPKKSPRKRSASP
What is the function of this protein?
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
What are the official names of this protein?
Histone H1, sperm.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RL27_RICM5
Sequence: MATKKAGGSSRNGRDSAGRRLGVKKADGQYVIPGNIIVRQRGTKIHPGTNVGLGKDHTIFALIEGRVEFLTKRNHKIVNVKEIASTY
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.