PharMolix/UniProtQA huggingface dataset:
Protein: APT_ENT38
Sequence: MTATAQQLEYLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALSIELLVERYKNAGITKVVGTEARGFLFGAPVALEMGVGFVPVRKPRKLPRETIAESYELEYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVTDAAFIINLFDLGGEQRLEKQGITSYSLVPFPGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_LYSTE
Sequence: MARGPKKHLKRLNAPKSWMLGKLGGVYAPRPSTGPHKLRECLPLLIFLRNRLKYALTNCEVTKITMQRLIKVDGKVRTDSNYPLGFMDVVTIEKTGEFFRLIYDVKGRFSIHRISNEEAKYKLCKVRRVQTGPKGVPFLVTHDGRTLRYPDPVIKVNDTIQLEIATNKILDSIKFDSGNLCMITGGRNLGRVGTVVSRERHPGSFDICHIKDSQGHTFATRMNNVFIIGKGSKAYVSLPRGKGVKLSIAEERDKRLAAKGAN
What are the official names of this protein?
40S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
Protein: PUR9_ECO24
Sequence: MQQRRPIRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLLAEKGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDAIMEEHQIQPIDMVVVNLYPFAKTVAREGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEMDDNEGSLTLATRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNLNFIKKQDMRYGENSHQQAAFYIEENVKEASVATATQVQGKALSYNNIADTDAALECVKEFAEPACVIVKHANPCGVAISNSILDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAIISRQFVEVIIAPSASEEALKITAAKQNVRVLTCGQWGERVPGLDFKRVNGGLLVQDRDLGMVGAEELRVVTQRQPTEQELRDALFCWKVAKFVKSNAIVYAKNNMTIGIGAGQMSRVYSAKIAGIKAADEGLEVKGSSMASDAFFPFRDGIDAAAAAGVTCVIQPGGSIRDDEVIAAADEHGIAMLFTDMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: TRUB_PYRCJ
Sequence: MKCGSREVFVKLEEGTNPQWGKPPSSRSAEEHIRYSFLILDKPRGPTSHEVAAWVKKILGVERAGHSGTLDPKVSGVLPVAVAEGTKVLMALSRADKVYIAVAKFHGDVDVENLRRVLQELQGEIYQKPPLRSAVKRQLRTRRVYSLELLELDGRYAVLKMHVEAGTYARKLIHDLGEILGVGANMRELRRVAVSCFTEDEAVTLQDLADAYYIWKKYGDDTYLRRVLLPIEEIARPLPKIWVRDSAVDALCNGAPLAAPGVAKFEHPFSRGDLVAYFTLKGELIGIGRALVDSEEVKKMEKGLVARTDRVVMPRGTYPPMWRRGGKSFKSGT
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
Protein: CPCF_PSETP
Sequence: MTDRLSQLIQAVEEADSSKLLLEAVQNLAAARLEGAIPILIEALSYNNPGAAVASVDGLILLGSAAVPPLLELLDMHNYTARAWAIRALAGIGDPRGLVTLLGVATADFAMSVRRAAVKGLGTMKWHWFPDELREIAQEEALDALLFVAQQDEEWVVRYASVVGLQSLAIAIAEAHPTWLAEIQTQFNLMSCNDEVLAIRGRVCVAQQKLQQKIQQLKSDSFHKSIEIKETEEKKSPLTSNDWQDILNQLYEIKRQERINSGSEGDPRRFQQLAAAITETNN
What is the function of this protein?
Required for the chromophorylation of the CpcA gene product.
What are the official names of this protein?
Phycocyanobilin lyase subunit beta, Phycocyanin-1 operon protein CpcF.
What is the protein family that this protein belongs to?
Belongs to the CpcE/RpcE/PecE family.
Protein: LUXS_HELP2
Sequence: MKTPKMNVESFNLDHTKVKAPYVRVADRKKGVNGDVIVKYDVRFKQPNQDHMDMPSLHSLEHLVAEIIRNHANYVVDWSPMGCQTGFYLTVLNHDNYTEVLEVLEKTMQDVLKATEVPASNEKQCGWAANHTLEGAKNLARAFLDKRAEWSEVGV
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: TAD1_BPPSB
Sequence: MRELKHELLPTRHTQVFHEDKDKMEFNAPHHFVVVPAGSPLVDQQIHYGRGGNSKKVTVKDFAGKLATVNFQLGPVTEHGANGVMNEDLIAMVITRLQYFQNSEFNCRENAMAITKLEEALMWLNKRTAEREQRGVEGTHEK
What is the function of this protein?
Blocks activity of the Thoeris antiviral defense system (ThsA and ThsB, AC J8G6Z1, J8G8J6) when expressed in B. subtilis normally susceptible to SBSphiJ group phages.  When added to phage SBSphiJ (which does not naturally encode this gene) confers resistance to Thoeris.  Inhibits Thoeris upstream of ThsA (PubMed:36174646).  Probably acts by binding and sequestering cyclic ADP-D-ribose signal molecules produced upon viral infection (3'cADPR or 2'cADPR); sequestration prevents the signal from activating the ThsA of the Thoeris antiviral defense system (Probable).
What are the official names of this protein?
Thoeris anti-defense 1, Tad1.
What is the protein family that this protein belongs to?
Belongs to the Tad1 family.
Protein: AJAP1_XENTR
Sequence: MWITQLLGIRSGPPLGSHAWILIAIFQLAMDFIICESESPGKAYKHLQRPSLVRRVHKVALWSPTELLKLRNQKQFWNPINNEHPVLPIERKHYKTYHENLFFSRNVPLKYSTMKNSHYSSQQIKHTVKTTNLNRSKRQLQSRSWDNLKRFLDSGSQPTTVSEFILWGPTGDDDVESSTFPGIYETTRTSTVHARTTLLETTTTTTASTTTNVKVTTLQNPGIHNGKKSPGRISTTDPNPGNGKTARPPRIPNDTSGLAVHQIITITVSLIMVIAALITTLVLKNCCAQSGNARRNSHQRKINQQEESCQNLTDFTPASVPSNMDIFTAYNETLHCSHECIRTPVPVYTDEALHQTGAFKTTFNGNRPTSSDRHLIPVAFVSEKWFEISC
What is the function of this protein?
May play a role in cell adhesion and cell migration.
What are the official names of this protein?
Adherens junction-associated protein 1.
What are the subcellular locations of this protein?
Basolateral cell membrane; Single-pass type I membrane protein. Apical cell membrane; Single-pass type I membrane protein. Cell junction, adherens junction. Note=Mainly basolateral.
Protein: NS1_I82A8
Sequence: MDSNTITSFQVDCYLWHIRKLLSMRDMCDAPFDDRLRRDQKALKGRGSTLGLDLRVATMEGKKIVEDILKSETDENLKIAIASSPAPRYITDMSIEEISREWYMLMPRQKITGGLMVKMDQAIMDKRIILKANFSVLFDQLETLVSLRAFTEDGAIVAEISPIPSMPGHSTEDVKNAIGILIGGLEWNDNSIRASENIQRFAWGIRDENGRPPLPPKQKRYMARRVESEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: M3K7_PONAB
Sequence: MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQSESGRLSLGASRGSSVESLPPASEGKRMSADMSEIEARIAATTAYSKPKRGHRKTASFGNILDVPEIVISGNGQPRRRSIQDLTVTGTEPGQVSSRSSSPSVRMITTSGPTSEKPTRSHPWTPDDSTDTNGSDNSIPMAYLTLDHQLQPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEIALLLQRKQELVAELDQDEKDQQNTSRLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQKRQGTS
What is the function of this protein?
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway.  Plays an important role in the cascades of cellular responses evoked by changes in the environment.  Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR).  Ceramides are also able to activate MAP3K7/TAK1.  Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K1/MEK1, MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7.  These MAP2Ks in turn activate p38 MAPKs, c-jun N-terminal kinases (JNKs) and I-kappa-B kinase complex (IKK).  Both p38 MAPK and JNK pathways control the transcription factors activator protein-1 (AP-1), while nuclear factor-kappa B is activated by IKK.  MAP3K7 activates also IKBKB and MAPK8/JNK1 in response to TRAF6 signaling and mediates BMP2-induced apoptosis.  In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK1, but not that of NF-kappa-B (By similarity).  Promotes TRIM5 capsid-specific restriction activity (By similarity).  Phosphorylates RIPK1 at 'Ser-321' which positively regulates RIPK1 interaction with RIPK3 to promote necroptosis but negatively regulates RIPK1 kinase activity and its interaction with FADD to mediate apoptosis (By similarity).
What are the official names of this protein?
Mitogen-activated protein kinase kinase kinase 7.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Although the majority of MAP3K7/TAK1 is found in the cytosol, when complexed with TAB1/MAP3K7IP1 and TAB2/MAP3K7IP2, it is also localized at the cell membrane.
Protein: UPPP_MYCMM
Sequence: MSAVAAMSWWQVISLAVVQGLTEFLPVSSSGHLAVVSRVFFSDDAGASFTAVTQLGTEAAVLVYFARDIVRILRAWFDGLVVTSHRNADYRLGWYVIIGTIPICVMGLLFKDEIRSGVRNLWVVATALVVFSGVIALAEYLGRQSRHVEQLTWRDGLVVGVAQTLALVPGVSRSGSTISAGLFLGLDRELAARFGFLLAIPAVFASGLFSLPDAFHPVTEGMSATGPQLLVATLIAFVVGLAAVSWFLRFLLRHSMYWFVGYRVVVGVVVLILLATGTVAAT
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PED1B_RAT
Sequence: MVRLLASEVQQLLHNKFVVVLGDSVHRAVYKDLVLLLQKDCLLTNKQLRTKGELSFEKDQLMMGGELDTLHNRTDYREVREFCSDHHLVRFYFLTRVYSEYMESVLKELQSGNHAPDVIIMNSCLWDVSRYGRNSLSSYRQNLENLFGRMDEVLPKSCLLVWNTAMPLGDKIKAAFLPQKCKGQYPRISVATLKKKVTQANFYSHAEATKHYFDVLDLNFHFRQARKHLQGDGVHWNEHAHRKLSYLLLAHMADAWGVELPHRDPWEPGFEAWESSGQVEERQPQDNIGPQFAQSPPYPFPRPPPLLPSPGLPIRPPPLLGCPLPPPQPMPPLPLYPQVSYFSSDPVFQSDEFYIHSDSPSSNHTGYAFEGDFSFYPQPPMPNFRPPCHQRQAPVVHRGFPRHFPRGPYMPWRERPRRPQKHAPACLESRPQ
What are the official names of this protein?
PC-esterase domain-containing protein 1B, Protein FAM113B.
What is the protein family that this protein belongs to?
Belongs to the PC-esterase family.
Protein: COAE_PSEPG
Sequence: MATAAFTPWILGLTGGIGSGKSAAAERFVELGVHLVDADQAARWVVEPGRPALASIVERFGPGVLQADGQLDRAALRQLIFADPAQRKWLEQLLHPLIGQEIFSYLAKAQSPYAIYVSPLLIESGQYHKTQRVLVIDAPQELQIARTLARDNTSAEQVQAILQAQLAREERLRHADDVLVNDGDLAALHEQIDRLHHFYLTLKGGQP
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTF2_PONAB
Sequence: MRDSTGAGNSLVHKRSPLRRNQKTPTSLTKLSLQDGHKAKKPACKFEEGQDVLARWSDGLFYLGTIKKINILKQSCFIIFEDSSKSWVLWKDIQTGATGSGEMVCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFKAEKEPEGTSHEFKIKGRKASKPISDSREVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEPLLDKESISENPTLDLPCSIGRTEGTAHSSNTSDVDFTGASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAAIPHLRRRRGRLPRRALQTQNSEIVKDDEGKEDYQFDELNTEILNNLADQELQLNHLKNSITSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS
What is the function of this protein?
Polycomb group (PcG) protein that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex, thus enhancing PRC2 H3K27me3 methylation activity (By similarity).  Regulates the transcriptional networks during embryonic stem cell self-renewal and differentiation.  Promotes recruitment of the PRC2 complex to the inactive X chromosome in differentiating XX ES cells and PRC2 recruitment to target genes in undifferentiated ES cells.  Required to repress Hox genes by enhancing H3K27me3 methylation of the PRC2 complex.  In some conditions may act as an inhibitor of PRC2 activity: able to activate the CDKN2A gene and promote cellular senescence by suppressing the catalytic activity of the PRC2 complex locally.  Binds to the metal-regulating-element (MRE) of MT1A gene promoter (By similarity).
What are the official names of this protein?
Metal-response element-binding transcription factor 2, Metal regulatory transcription factor 2.
What is the protein family that this protein belongs to?
Belongs to the Polycomblike family.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to chromatin as part of the PRC2 complex.
Protein: Y3064_BACCZ
Sequence: MLQALLIFVLQIIYVPILTIRTILLVKNQTRSAAAVGLLEGAIYIVSLGIVFQDLSNWMNIVAYVIGFSAGLLLGGYIENKLAIGYITYQVSLLDRCNELVDELRHSGFGVTVFEGEGINSIRYRLDIVAKRSREKELLEIINEIAPKAFMSSYEIRSFKGGYLTKAMKKRALMKKKDHHVS
What are the official names of this protein?
UPF0316 protein BCE33L3064.
What is the protein family that this protein belongs to?
Belongs to the UPF0316 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL17_BORAP
Sequence: MKAKLGFNRLSRKSSHRRALLKNMVISFLKHEKISSTKAKLFEVKRFSERLITKAKVDTVHNRRELSKFIHDKYILNKLFTKISPVFRQRSGGYTRMIKLGKRYGDAAEMAILELVEKPLKAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: ULAF_ECOLC
Sequence: MQKLKQQVFEANMELPRYGLATFTWGNVSAIDRERGLVVIKPSGVAYETMKAADMVVVDMSGKVVEGEYRPSSDTATHLELYRRYPSLGGIVHTHSTHATAWAQAGLAIPALGTTHADYFFGDIPCTRGLSEEEVQGEYELNTGKVIIETLGNAEPLHTPGIVVYQHGPFAWGKDAHDAVHNAVVMEEVAKMAWIARSINPQLNHIDSFLMNKHFMRKHGPNAYYGQK
What is the function of this protein?
Catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate.  Is involved in the anaerobic L-ascorbate utilization.
What are the official names of this protein?
L-ribulose-5-phosphate 4-epimerase UlaF, L-ascorbate utilization protein F, Phosphoribulose isomerase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. AraD/FucA subfamily.
Protein: ISPT_CHLMU
Sequence: MSLALEQANPIQENFLREPPLPKHIAIIMDGNRRWQKKHEQFCKSNAISGHRRGADSIPQIVDTAALLGVEALTLFAFSTENFSRSKTEVAELFSLFNSQLHSKLSFLHDREIRLRCIGDLSKLPQELQNNIAKAVSATTHYSHMELIFAINYGSKNELVRAFKELHQDLTNKKISINEISEELISSYLDTSGLPDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTAHDLLEAIKTYQQRSRRGGK
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: QUEA_SERP5
Sequence: MRVADFSFELPESLIAHYPQPERSGCRLLQLDGPSGELKHGVFTDLLDNLEAGDLLVFNNTRVIPARMFGRKVSGGKIEVLVERVLDDHRVLAHVRASKAPKPGTDLLLGDDESIAATMVARHDTLFELRFNDERDVFTILNAVGHMPLPPYIDRPDEDADRELYQTVYSEKPGAVAAPTAGLHFDEPLLAALREKGIEMAFVTLHVGAGTFQPVRVETIEEHVMHAEYAEVPQEVVDAVLACKARGKRVVAVGTTSVRSLESAANASKEALIAPFFDDTSIFIFPGYHYQVVDALVTNFHLPESTLIMLVSAFAGYKNTMHAYQQAVAEQYRFFSYGDAMFISRNPQAEQESVGA
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_HELPH
Sequence: MEKIRLKLKAYDHRVLDRSVVAIVEAVKRSGSEIRGPIPLPTKNKRYTVLRSPHVNKDSREQFEIRVYSRLIDIISATPETVDSLMKLDLAPEVDVEVTSMETK
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: SECA1_MAGMM
Sequence: MFSAIARKLFGSRNDRYLRSLQPLVDRINGLEAEYEALSDSELTAMTYAFKARLEKGETLDDLLPEAFAVVREGSKRVLGMRHYDVQLIGGIVLHQGKISEMKTGEGKTLVATLSLYLNALSGKGAHLVTVNDYLARRDAEWMGKLYQFLGLSVGVIIHGIEDQQRKAAYNADITYGTNNEFGFDYLRDNMKFSLEEMVQRPLNYAIVDEVDSILVDEARTPLIISGPTEDSTDKYYKVDRLIPQLEKERHYTLDEKQRSVTFTEEGNEQIEQLMRQAGLLRDGDLYDLHNIEMVHHVNQALKAHAMFEVDRDYIVKDGQVVIIDEFTGRMMPGRRYSDGLHQALEAKEQVVIQNESQTLASITFQNLFRLYNKLAGMTGTADTEAAEFQSIYNLEVVIIPTNRDMVRIDRDDMVFRTLEEKLKAVAEDIKVSYEKGQPVLVGTVSIEKSEMVSHFLKKLKIPHEILNAKHHEREAEIVAQAGRPRAVTIATNMAGRGTDIQLGGNLEMRLKKEIDPEASPAERTQQEIQIRTEYEQDKALVLASGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSGFYLSLQDDLMRIFGSERMDGMLKKLGLQDGEAIVHPWINKAVESAQKKVEGRNFDIRKNLLKFDDVMNEQRKVIYDQRKELMENEDIRDFIDEIREEVVHALVDSHLGEDVYPEEWDAKGFREAMLNQFNLDLNVESWKHEEGVTHLVAKERAMAAVKAYSEAREARLGPPLMRYLEKSIMLQVLDTLWKEHLLNMDHLKEGIHLRGYAQKDPLNEYKREAFQLFSMLLQRIREEAIEFLGKVEVQQPEEVAAYEAELAEARNQQMSLNHPESGSWGGEGEGPSSEGAPHLPFKRDGEKVGRNQACPCGSGKKYKQCCGKLS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: RLMM_SHESR
Sequence: MKNLFLFCRAGYEKECAAEIQQRAAELNVGGFVKANNNDAYVVYQCFEEDGGDILVKQLPLDSLIFARQMFAASELLADLPESDRVSPIVAALSDVSKAGELRVETPDTNEAKELSAFCRKFTVPLRQHLKKSGSLLAQENPKRPIIHVCFIGPGRAYVGYSFSNNSSPYFMGIPRLKMAADAPSRSSLKLDEAFAQFVPKEEQEERVRSGMNAVDLGACPGGWTYQLVRRGMMVSAVDNGPMNEKLMETGQVKHFREDGFRFEPQRKNIYWLVCDMVEKPARVAELIEAWAINGWFKEAIFNLKLPMKSRYKEVMAILNTMQEILKENGINEFQLQCKHLYHDRDEVTVHLWIRPSQAWN
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_BORA1
Sequence: MSGNTLGSLFRVTNFGESHGPAIGCVVDGCPPGLPLDAADIQRELDRRRPGTSRHVTQRQEADQVEILSGVYEGVTTGTPIGLLIRNIDARSKDYSNIADTFRPGHADYSYWKKFGQRDPRGGGRSSARLTAPTVAAGAIAKKWLAQQHGTIVRGYMSQLGPIEIPFVSWDEVPNNPFYAPNAAIVPELEAYMDALRRDGDSIGARIEVVAEHLPAGWGEPIYDRLDADIAHAMMGLNAVKGVSIGAGFGSITQRGSEHGDEITPDGFLSNHAGGVLGGISTGQPVTVSLAIKPTSSIRVERRSVNRAGEPVNVQTLGRHDPCVGIRATPIAEALLALVLIDHALRHRGQCG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: HRI1_YEAS7
Sequence: MPALLKRLLFQVGPHPNERTFTLSSVSTDGHYISLRPFVKPSGDELSFPFEWAFAGTNETVKVNDQGNGVVTQDFNFWLDTNVYLNVPNTHRGEVNTTWKNWDSGCVEETGAVYPFGADKESVSFRELWQPVDPSREDLVIVSPNNEKFSSNARSIVLKVTDEAYDGLVIVIGRWIQGFLSQKNNNTIEGLNFIRLLEKDSGKSEFLLSYGKEVNKIPQSYENLKKGSTVTSNGLNWEVIEYHA
What are the official names of this protein?
Protein HRI1, HRR25-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the HRI1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS5_LACLS
Sequence: MAENRRNDREQSEFEERVVSINRVTKVVKGGRRLRFAALVVVGDRNGRVGFGTGKAQEVPEAIRKAIEAAKKNLITVPMVGATLPHEALGVFGGGKILLKPAVEGAGVAAGGAVRAVLELAGVADVTSKSLGSNTPINVVRATVDGLTQLKRAEEVAALRGKSVSDFA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: PGSA_MYCTO
Sequence: MSRSTRYSVAVSAQPETGQIAGRARIANLANILTLLRLVMVPVFLLALFYGGGHHSAARVVAWAIFATACITDRFDGLLARNYGMATEFGAFVDPIADKTLIGSALIGLSMLGDLPWWVTVLILTRELGVTVLRLAVIRRGVIPASWGGKLKTFVQAVAIGLFVLPLSGPLHVAAVVVMAAAILLTVITGVDYVARALRDIGGIRQTAS
What is the function of this protein?
Probably catalyzes the synthesis of phosphatidylglycerophosphate by transferring a phosphatidyl group from CDP-diacylglycerol to glycerol 3-phosphate.
What are the official names of this protein?
Probable phosphatidylglycerophosphate synthase, PGP synthase, PGPS, CDP-diacylglycerol--glycerol-3-phosphate phosphatidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EMTA_CROS8
Sequence: MKLRWLMWLVVFLAGCSSTPDYKNPPWNPEVPVKRAMQWMPITEKAGNAWGVSPRLVTAIIAVESGGNPTLVSKSNAVGLMQIKASTAGREVYRYMGWSGQPSSSELKNPERNISIGTAYLSILEHGVLKGIEAPETMQYALVVSYVNGAGALLRTFSSDRKAAIEKINDLSPDEFVEHVAKNHPAPQAPRYIWKVQQAMNAM
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.  Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain.
What are the official names of this protein?
Endo-type membrane-bound lytic murein transglycosylase A, Peptidoglycan lytic endotransglycosylase.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RS17_XANOP
Sequence: MSDNNEKQTLRTVEGRVVSNKMDKTVTVLVERQVKHALYGKYIKRSTKLHAHDADNACNEGDVVRVTEIAPMSKTKNWRVVEIVTRSAE
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.