PharMolix/UniProtQA huggingface dataset:
Protein: TMCAL_THEM4
Sequence: MKVLGVIVEYNPFHNGHLYHLQQAKKIVSPDYVIAIMSGNFCQRGEPAIINKFARAEIALKNGIDVVFELPTVYALQDAGGFAFGAITLLDKLTVVTDVVFGSESADKNFITTVAKTLLENPDKFDNLLKIELKKGLSFPNARKFALKKFLNENEDFLKMIENSNDILGIEYVKSILKLKSKINYHLIKRIGAKYNDTELESKYSSATAIRNAIVRNNPFETYVPQTSYKVLKREFSYGRGPVSLENMEQFILTFLRLKHRKDFESIYSFTEGLDQRFIKAIKTSKKLSDFLEKVKTKRFTYSRIRRAIFHALFDFKKEYIEFSNKLGTQYARILGFTKKGQKLLSKIKKASKIPIISNPSLHEKVLKKVLTDKDRKWEVNKKLFIWQFEKDIVASNIYTMFYPQKNERKYGLDFRKPIIEGENE
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_CERS4
Sequence: MAHPEQQYLDLLAQTLERGDRRVDRTGVGTLSLFGAMLRFDLSGGQVPILTTKRVYWKTAVKEMLWFLTGGTNIRPLLQENVRIWSDWPLAAYRRESGEEISQAAFEQRVLEDEAFAARWGELGPVYGKQWRRWLGPDGHEHDQIAALIETLRTNPSSRRMLFHAWNVAEVGQMALPPCHMVYQYHVTSDGRLNALLYQRSVDLLLGAPFNFVGAAALQLMIAQQAGLVPGDLVWVGGDTHLYLNHLDQAREQTGRAPRDWPRMRLLRRADSIDDYRIEDFAVEGYDPHPAIAAEVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_BURMA
Sequence: MTATLIDGNALSKTLRAQAAERAAALAARGHRPGLAVILVGDNPASEVYVRNKIKACEDNGFFSLKDRYPATLSEPELLARIDELNRDPKIHGILVQLPLPAHIDSHKVIEAIAPEKDVDGFHVANAGALLTGKPLFRPCTPYGVMKMFEAYKIPLQGANAVVIGRSNIVGKPMALLLLEAGATVTICHSKTCELAAHTRAADIVVAAVGKRNVLTADMVKPGATVIDVGMNRNDEGKLCGDVDFAGVSQVAGHITPVPGGVGPMTITMLLVNTIEAAERAAAAA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: IOLG_SALA4
Sequence: MTLKAGIVGIGMIGSDHLRRLANTVSGVEVVAVCDIVAGRAQAALDKYAIEAKDYNDYHDLINDKDVEVVIITASNEAHADVAVAALNANKYVFCEKPLAVTAADCQRVIEAEQKNGKRMVQIGFMRRYDKGYVQLKNIIDSGEIGQPLMVHGRHYNASTVPEYKTPQAIYETLIHEIDVMHWLLNEDYKTVKVYFPRQSSLVTTLRDPQLVVMETTSGINIVVEVFVNCQYGYDIHCDVTGEKGMAELPTVASAAVRKAAKYSTDILVDWKQRFIDAYDIEFQDFFDRLNAGLPPAGPTSWDGYLAAVTADACVKSQETGNTEIVELPSKPDFYK
What is the function of this protein?
Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).
What are the official names of this protein?
Inositol 2-dehydrogenase, Myo-inositol 2-dehydrogenase, MI 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: SYL_GEOSW
Sequence: MSFNHREIEKKWQEYWEKNKTFKTVDDDDKPKFYVLDMFPYPSGAGLHVGHPEGYTATDILARMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTEKNINTFRRQIKSLGFSYDWDREINTTDPNYYKWTQWIFLKLYEKGLAYMDEVPVNWCPALGTVLANEEVIDGKSERGGHPVIRKPMKQWLLRITAYADRLLEDLEELDWPESVKEMQRNWIGRSEGAEIRFEVDGHDETFTVFTTRPDTLFGATYTVLAPEHPLVEKITTPEQKAAVEAYLDAIKSKSDLERTDLAKEKTGVFTGAYAIHPVTGEKLPIWIADYVLMSYGTGAIMAVPAHDERDYEFAKKFNLPIKEVVAGGDIAKEAYTGDGEHINSDFLNGLNKEEAIKKMIEWLEANGKGQKKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTMTPVPEEELPLKLPKTDKIKPTGTGESPLANIEEWVNVVDPKTGKKGRRETNTMPQWAGSCWYYLRYIDPHNDKQLADPEKLKKWLPVDVYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLFNQGMILGENNEKMSKSRGNVVNPDDIIESHGADTLRLYEMFMGPLEASIAWSTKGLDGARRFLDRVWRLFVDENGNLNPKIVDNPETDTLERVYHQTVKKVTEDYEALRFNTAISQLMVFINEAYKAPVLPKEYMEGFVKLLSPVCPHIGEELWEKLGHNNTIAYEPWPTYDESKLVEEEVEIVVQVNGKVRAKLRVPADISKEKLEQLAMEDEKIKEHIAGKTVRKVITVPGKLVNIVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y810_FRATT
Sequence: MNFDMSKLMQQAQKMQEQMKKAQQERENMEVIGESGAGLVTVTMTGKYDVKSVSIDNSLMSEDKEILEDLIAAAVNSAVKKVEENSTASSDIYKMAKDAGIDLPSGINFPFK
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein FTT_0810c.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: DPOL_HBVC8
Sequence: MPLSYQHFRKLLLLDDEAGPLEEELPRLADEGLNHRVAEDLNLGNPNVSIPWTHKVGNFTGLYSSTVPVFNPEWQPPSFPHIHLQEDIINRCQQYVGPLTVNEKRRLKLIMPARFYPNLTKYLPLDKGIKPYYPEHAVNHYFKTRHYLHTLWKAGILYKRETTRSASFCGSPYSWEQELQHQTSTRHGDESFCSQSSGILSRSPVGPCVRSQLKQSRLGLQPQQGSMARGKSGRSGSIRARVHPTTRRSFGVEPSGSGHIDNSASSASSCLHQSAVRKTAYSHLSTSKRQSSSGHAVEFHNIPPSSARSQSEGPIFSCWWLQFRNSKPCSDYCLTHIVNLLEDWGPCTEHGEHNIRIPRTPARVTGGVFLVDKNPHNTTESRLVVDFSQFSRGSTHVSWPKFAVPNLQSLTNLLSSNLSWLSLDVSAAFYHIPLHPAAMPHLLVGSSGLPRYVARLSSTSRNINYQHGTMQDLHDSCSRNLYVSLLLLYKTFGRKLHLYSHPIILGFRKIPMGVGLSPFLLAQFTSAICSVVRRAFPHCLAFSYMDDVVLGAKSVQHLESLFTSITNFLLSLGIHLNPNKTKRWGYSLNFMGYVIGSWGTLPQEHIVLKLKQCFRKLPVNRPIDWKVCQRIVGLLGFAAPFTQCGYPALMPLYACIQSKQAFTFSPTYKAFLCQQYLHLYPVARQRSGLCQVFADATPTGWGLAIGHRRMRGTFVAPLPIHTAELLAACFARSRSGAKLIGTDNSVVLSRKYTSFPWLLGCAANWILRGTSFVYVPSALNPADDPSRGRLGLYRPLLHLPFRPTTGRTSLYAVSPSVPSHLPSRVHFASPLHVAWRPP
What is the function of this protein?
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid.  Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA).  The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
What are the official names of this protein?
Protein P.
What is the protein family that this protein belongs to?
Belongs to the hepadnaviridae P protein family.
Protein: YAEP_SALTY
Sequence: MEKYCELVRKRYAEIASGDLGYVPDALGCVLKVLNEVAADSALSESVREKAAYAAANLLVSDYVNE
What are the official names of this protein?
UPF0253 protein YaeP.
What is the protein family that this protein belongs to?
Belongs to the UPF0253 family.
Protein: SYGB_PSET1
Sequence: MSAQNLLVEIGTEELPPKALRKLAEAFAANLTAELETLELAHQGVSWYASPRRLGLRVIALDAKQQDKEVEKRGPAIKAAFDADGNPTKAAMGWARGCGIEVKDAQTLETDKGAWLLHLAKVAGQETKTLMVDVINKALAKLPIPKPMRWGANKTQFIRPVHTVTILLGDELVTGEVLGKQVSNQLQGHRFHHPEKITINHADDIFDVLKSAYVIADYEQRKAQIRAQIEAAAKAINAVVAMDEDLLEEVTSLVEWPVTLTATFEEEFLAVPAEALIYTMKDDQKYFPLLDQNGKLLNKFLFVSNIESKDPSVVISGNEKVVRPRLADAQFFFESDKKKTLESRLESLDSVLFQKQLGTLKDKSARISELAGYIAQQLGADKELAQRAGLLSKTDLMTEMVMEFTDIQGVMGMHYARFDGEAEDVALAQNEQYMPRFAGDSLPTNLISCAVAIADKFDTLVGIFGIGQAPKGDKDPFALRRAAIGALRIMVEKELPLDILDLVAKSQTLFGDKLTNLNVSTDVFEFMLGRFRAWYQDEGIEVDVIQAVLARRPTKPVDFDRRVKAVSHFRTLDAAEALAAANKRVSNILAKNDITSEGNVDESLLTDDAEKVLAAQVAKFATELAPLYASGNYQEALSQLAGIRQSVDSFFDNVMVMADDEAVKQNRLALLSQLSGLFLGIADISVLQK
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2361_CERS5
Sequence: MIVTTTPSVEGHQIATYHGIVTGEAILGANVIRDLFAGITDFIGGRSGAYEKELGRARETALSEMEQAARAKGANAVVGVDLDYEVINNMLMVSASGTAVTIA
What are the official names of this protein?
UPF0145 protein Rsph17025_2361.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: YL345_YEAST
Sequence: MPNVLSDDEELLNGLGSEIMKPSRQGNHMARTVKRWVNKERATTADLKNVNIDGVHGPVNTESYISPGQLYSTDSGNLFHAGRILVVLVGLPATSKTLLSVAITRYTRWLGVRTKSFHFSEYKESAKNIPSDYFCVVPTSKEGVAFVEKLRMQMLNDILAFFNDLSGQLAIYDALNIRKIDRKNLETTFSEIGVKVLFIESIVSDQEIMNRNIALALESNDYKGLSTDEAIDEYMRRLSVNEPYYEMMTHDEELSYIKYINLGKQIIVKDNIHGYLVNKIVFFLMNLRQKKGCVYFARCGTSDKDNYIHDEELNEEGIHYSQVLKDFVLQRIKQKRQAKKNSDSLVEVIDGSHDEDLKTSLIVWTGPRKRTHDTALFFSKEGIKVQQRSELRQLNPGSIADLTDQQIMDKFPSEYKESLKDPYHFRFPRAESYHDLAVRMEPLLLEMEHTSKDILIIAHESTLRVLYGYLMACTCVELPNLNFTRDKLVEISFSPFCNTVELLNIPLTS
What is the function of this protein?
Synthesis and degradation of fructose 2,6-bisphosphate.
What are the official names of this protein?
Putative 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase YLR345W.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phosphoglycerate mutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_HYDCU
Sequence: MAKANSRVKKKAKQVVTDAVAHVHATFNNTIVTITDRQGNALCWATSGGSGFRGSRKSTPFAAQVAAERAGQMATEYGVKNMDVMVKGPGPGRDSAVRGLNSVGFKITSISDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: VSP03_TRIST
Sequence: MVLIRVLANLLILQLSYAQKSSKLVVGGDECNINEHPFLVLVYHDGYQCGGTLINEEWVLTAAHCDGKKMKLRFGLHSKNVPNKDKQTRVPKEKFFCLSSKYFIKWGKDIMLIRLNRPVNNSTHIAPLSLPSSPPSQNTVCNIMGWGTISPTKEIYPDVPHCANISILDHAVCRAFYPGLLEKSKTLCAGILEGGKDICQGDSGGPLICNGQIQGIVSVGGNPCAEPRVPAIYTKVFDHLDWIKSIIAGNTAATCPL
What is the function of this protein?
Snake venom serine protease that may act in the hemostasis system of the prey.
What are the official names of this protein?
Snake venom serine protease KN3, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GRS11_ORYSJ
Sequence: MAAVREVGSKAELEAAAGGARAAAVHFWAAWCEASKQMDEVFAHLAVDFSHAVFLRVEAEEQPEISEAYGVTAVPYFVFLKEGKTVDTLEGANPASLANKVAKLAGPASVAESAVPASLGVAAGPAVLEKVQEMAQQNGASATSSAEDALNKRLEQLVNSHPVFLFMKGTPEQPRCGFSRKVVDVLKQEGVEFGSFDILTDNDVREGMKKFSNWPTFPQLYCKGELLGGCDIVIAMHESGELKDVFKEHNIPLQPQGSKNEEAVKAKPDTEKSGAVSEPALLTAAQKERLESLVNFSTVMAFIKGTPEEPKCGFSGKLVHILKQEKIPFSSFDILTDDEVRQGLKLLSNWPSYPQLYINGELVGGSDIVMEMHKSGELKKVLSEKGIVAKESLEDRLKALISSAPVMLFMKGTPDAPRCGFSSKVVNALKQAGVSFGAFDILSDEEVRQGLKTYSNWPTFPQLYYKSELIGGCDIVLELEKSGELKSTLSE
What is the function of this protein?
May only reduce GSH-thiol disulfides, but not protein disulfides.
What are the official names of this protein?
Monothiol glutaredoxin-S11.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. CGFS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_CAMLR
Sequence: MSSYIPYVVEKTSRGERSYDIYSRLLKDRIIMLSGEINDDLAASIVAQLLFLEAEDPQKDIYLYINSPGGVVTSGFSIYDTMNYIKADVSTICIGQAASMGAFLLSCGAPGKRFALPNSRIMIHQPLGGARGQATDIEIQAKEILRLKAILNDILAKNTKQKLSKIEKDTDRDFFMSAIEAKEYGLIDKVLEKSFK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FNDC8_HUMAN
Sequence: MASEALHQVGDGEEAVLKKENFNMMNALDQLPKPFSNPKSMNRTVTTKGLPLASKGNLVNFLEDDTINLLKPLPVEDSDCSSDETSISAFSSTLLNPIKLAVTQPNSSFFAGMLEGELNKLSFSPMAKNAENEDLALGPCPCPSKSQMATRGLLDLDNPELETETSSTHSESSVVVDLPDTPFIFEHTVNNSTAVISWTYALGKQPVSFYQLLLQEVAKTQENELPEAKNRPWIFNKILGTTVKLMELKPNTCYCLSVRAANTAGVGKWCKPYKFATLATDFSSFPENYPIQITVRRKEPRQKIVSIGPEEMRRLEDLEYLFPC
What are the official names of this protein?
Fibronectin type III domain-containing protein 8.
Protein: GRXS3_ORYSJ
Sequence: MQGARSAAAMAAAAADEEREVRRAVEEKPVVVVGRRGCCMAHVARRLLLGQGANPAVLEVGDDADPAALVDAALQARRRKDGGDKAAAGDGGGGAAVAFPAVFIGGRLVGGLDRLMAMHMAGELVPVLKQAGALWL
What is the function of this protein?
May only reduce GSH-thiol disulfides, but not protein disulfides.
What are the official names of this protein?
Monothiol glutaredoxin-S3.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. CC-type subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MPG1_CRYNJ
Sequence: MKALILVGGFGTRLRPLTLSWPKPLVEFCNKAMILHQIEALVKAGVKDIVLAVNYRPEVMVSVLKKTEEEFGINIHFSVETEPLGTAGPLALAREILGKDDSPFFVLNSDVTCVYPFEAFRDFHIAHKCEGSIMVTKVAEPSAYGVVVTKPNSTVIDRFVEKPVEFVGNRINAGIYIFNPSVLDRIELRPTSIEKEIFPAIAADQQLHSFDLQGFWMDVGQPKDFLAGTCLYLSHLTSQHSPLLTDPSQNKWVYGGNVMVDPSAEIDPTAVIGPNVVIGPDAKIGPGVRLQRCVIMSNATVRDHSWIANSIVGWNSTVGRWTRVENITVLGDDVTIKDELYVNGASVLPHKSISTSITEPRIVM
What is the function of this protein?
Involved in cell wall synthesis where it is required for glycosylation.  Involved in cell cycle progression through cell-size checkpoint (By similarity).
What are the official names of this protein?
Mannose-1-phosphate guanyltransferase, GDP-mannose pyrophosphorylase, GTP-mannose-1-phosphate guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_ECOHS
Sequence: MKNDVISPEFDENGRPLRRIRSFVRRQGRLTKGQEHALENYWPVMGVEFSEDMLDFPALFGREAPVTLEIGFGMGASLVAMAKDRPEQDFLGIEVHSPGVGACLASAHEEGLSNLRVMCHDAVEVLHKMIPDNSLRMVQLFFPDPWHKARHNKRRIVQVPFAELVKSKLQLGGVFHMATDWEPYAEHMLEVMSSIDGYKNLSESNDYVPRPASRPVTKFEQRGHRLGHGVWDLMFERVK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: TRMD_DEHMB
Sequence: MKIDVLTLFPEMFQSPFEESIFKRATDNNLVRLEIHNFRDFAHDKHHAVDDSPYGGGAGMLLKPEPLFEAVEDVLREDPTPAPVILLSPQGRSFNQEVARELAKHERLIIICGHYEGFDERVREHLSTDEISIGDFVLTGGELAAMVVIDAVSRLIPGVLGSGESSQDDSHSNGLLEHPHYTRPPVFRGWGIPDVLLSGNHAQINRWRRKESLRRTLKRRPDMFEKIPLSKADRKLVDEILAEENTQG
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_ELUMP
Sequence: MTIIIAGPTAGGKTDLALNLAKLIGGEVVSVDSRQVYKYLTVGTAKPEGEYKNGVYNVDGVNYHLVDFLDLDKTYNTGSFTADASNTAYNINKKGKTAIFAGGTGMYMQSYFGGMDVLPKADQALRAQLADIADKEGKQSLHKMLSEADPESAALIPSGNLHRVMRALEIFKLTGKKASELRTNGFADISQNNFMVYIEWDKEELNKRIEIRTQGMFGGMLKETQDMLAKGYTRNSPGLRSLGYAEVIDFIEGKKTKPEALERIVILTRQYAKRQRTWFARYKNMYKADGSALNAEQILAEYAAWKK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: MATK_GLETR
Sequence: MKEFQVYLELDRSLQHDFLYPLIFREYIYALAYDHGLNSSILVENLGYDNKSSLLIVKRLITRMYQQNHLILSANDSNKNQFWGYNKNLYSQIISEGFAVSVEIPFSLQLISSLEEAEIVKSYNLRSIHSIFPFFEEKFPYLNYVSDVRIPYPIHLEILVQTLRYWVKDASSFHLLRLFLYEYCNWNSLITPKKWISTFSKSNPRLFLFLYNFYVCEYESILIFLRNKSSYLRLTSSGVLFERIYFYAKIEHRVEVFDKDFPSTLWFFKDPFIHYVRYQGKSILSSRNTPFFMNKWKYYLIHLWQCHFYVWSQPGKIHINQLSEHSFYFLGYFSNVRLNPSVVRSQMLENSFIIENVMKKLDTTIPIIPLIRSLAKAKFCNVLGHPISKPVWADSSDFDIIDRFLRICRNLSHYYNGSSNKKSLYRIKYILRLSCIKTLARKHKSTVRVFLKRLGSKFLEEFFTEEEEILSLILPRASFTLQRLYRGRIWYLDIFYFHH
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SOAT1_MACFA
Sequence: MVGEEKMSLRNRLSKSRENPEEDEDQRKPAKESLEAPSNGRIDIKQLIAKKIKLTAEAEELKPFFMKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILEGEKNNHRAKDLRAPPEQGKIFIARRSLLDELLEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFSLLSYAFGKFPTVVWTWWIMFLSTFSVPYFLFQRWATGYSKSSHPLINSLFHGFLFMVFQIGILGFGPTYVVLAYTLPPASRFIIIFEQIRFVMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRNPTVRWGYVAMQFAQVFGCFFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLILFLTFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYAYKDFLWFFSKRFKSAAMLAAFAVSAVVHEYALAVCLSFFYPVLFVLFMFFGMAFNFIVNDSRKKPIWNVMMWTSLFLGNGVLLCFYSQEWYARQHCPLKNPTFLDYVRPRSWTCRYVF
What is the function of this protein?
Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol.  Plays a role in lipoprotein assembly and dietary cholesterol absorption.  Utilizes oleoyl-CoA ((9Z)-octadecenoyl-CoA) preferentially as susbstrate: shows a higher activity towards an acyl-CoA substrate with a double bond at the delta-9 position (9Z) than towards saturated acyl-CoA or an unsaturated acyl-CoA with a double bond at the delta-7 (7Z) or delta-11 (11Z) positions.
What are the official names of this protein?
Sterol O-acyltransferase 1, Acyl-coenzyme A:cholesterol acyltransferase 1, ACAT-1, Cholesterol acyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TGT_SHIB3
Sequence: MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPEEVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIRKITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAKRSRERFDSLGNKNALFGIIQGSVYEDLRDISVKGLVDIGFDGYAVGGLAVGEPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRKAIEEGKLESFVTDFYQRQGREVPPLNVD
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: OPF13_ARATH
Sequence: MGKKKMKLSSLFKGGAGGLLAVPLCYNAKTLSFRVGDDMIKTVNSVFFDHHHNNNNGGDLLEAETPESWFTNSSETASHSTESDQDLDAESLEMVVRGVVRSERLFFDPGVTSSILEEIEEKSKSDLKSKETVAVGEDRSTPIEEISVAVAMESEDPYGDFRRSMEEMVTSHGELAKDWESLESMLAWYLRMNGRKSHGVIVSAFVDLLSGLSDSGAGITSASVSDSARYSTAVSSLPSSPVYSLSQGQTEIQEEERRSC
What is the function of this protein?
Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors.
What are the official names of this protein?
Transcription repressor OFP13, Ovate family protein 13, AtOFP13.
What are the subcellular locations of this protein?
Nucleus.
Protein: MGSA_YERP3
Sequence: MELTTRTIAARKHIALVSHDHCKKSLLAWVMENRDLLAQHELYATGTTGNLVQKATGIDVHCLLSGPMGGDQEVGALISEKKIDILIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNRSTADFLIGSTLFSSEVTIAIPDYDRYMQQRLDLK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: CLCA_KLEP3
Sequence: MKAETPSFEAHQFVRVRRGDAVRRLIQRDKTPLAVLLMAAVVGTLAGLVGVAFEKSVNWVQNQRIGALAQVADHWYLVWPLAFILSALLAMVGYFLVRRFAPEAGGSGIPEIEGALEELRPVRWWRVLPVKFIGGMGTLGAGMVLGREGPMVQLGGNIGRMVLDIFRMRSPEARHTLLATGAASGLSAAFNAPLAGILFIIEEMRPQFRYNLISIKAVFTGVIMSSIVFRIFNGEAAIIEVGKLSNAPVNTLWLYLVLGMLFGCFGPLFNFLVLRTQDIFQRIHGGNIKTWVLMGGVIGGICGLLGLMQPSAVGGGFNLIPIAAAGNFSVGLLLFIFIARVVTTLICFSSGAPGGIFAPMLALGTLLGTAFGMAAIPLFPAYHLDAGTFAIAGMGALLAASVRAPLTGIVLVLEMTDNYQLILPMIITCLGATLLAQFLGGKPLYSTILQRTLAKQEAEQAAKAQQAPRENT
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges two chloride ions for 1 proton.  Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
H(+)/Cl(-) exchange transporter ClcA.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MIAA_STRPS
Sequence: MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLDIGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEGIHNRGKLAIIAGGTGLYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVDQAGLEIPQFNRRRAMRALEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHSPNVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIGESGVQDRILSQIEEFLDD
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.