PharMolix/UniProtQA huggingface dataset:
Protein: TRI8_FUSSP
Sequence: MALNRLVFSLSLWLGFIGAAQAASSEPLPPSKDPWYTAPPGFESAEPGTVLRVRPAPGNLTSITANSSASYNILYRTTDSHFKPTWAVTTLLVPELGPDSLAQQKFQQSALLSFQVPYDSADVDASPSYSMYSASNDSSAPYTAALGSGLFVSVPDYEGPLAAFTAGIISGYATLDSIRAVLSLGLGLNITNSPRAALWGYSGGAFATEWASELAVQYAPDLVAGPVVGAAMGAPLANITTFMHSVNGQATSGLVPNTLLGLTSQYPDVRKYLVSKLNDDSEYNRTGFLAAEGFTVTESGVAFAGIDINKYFQNGTDILNDPKILALVNREGIMGYHGVPKWPLFIYQAIPDEVTPISATDALVEKYCAVGADILYERNTVGSHYEETNNSYKAAVQWLEDVFSSQHDINRAQGCVIQDVTRNTTSGDLVRRKDVQKSVFDLWSAAW
What is the function of this protein?
Trichothecene C-3 esterase; part of the core gene cluster that mediates the biosynthesis of trichothecenes, a very large family of chemically related bicyclic sesquiterpene compounds acting as mycotoxins, including T2-toxin (PubMed:11352533, PubMed:12039755).  The biosynthesis of trichothecenes begins with the cyclization of farnesyl diphosphate to trichodiene and is catalyzed by the trichodiene synthase TRI5 (PubMed:3800398).  Trichodiene undergoes a series of oxygenations catalyzed by the cytochrome P450 monooxygenase TRI4 (PubMed:7651333).  TRI4 controls the addition of four oxygens at C-2, C-3, C-11, and the C-12, C-13-epoxide to form the intermediate isotrichotriol (PubMed:16917519).  Isotrichotriol then undergoes a non-enzymatic isomerization and cyclization to form isotrichodermol (PubMed:2317042).  During this process, the oxygen at the C-2 position becomes the pyran ring oxygen and the hydroxyl group at C-11 is lost (PubMed:2317042).  More complex type A trichothecenes are built by modifying isotrichodermol through a series of paired hydroxylation and acetylation or acylation steps (PubMed:11352533).  Isotrichodermol is converted to isotrichodermin by the acetyltransferase TRI101 (PubMed:10583973).  TRI101 encodes a C-3 transacetylase that acts as a self-protection or resistance factor during biosynthesis and that the presence of a free C-3 hydroxyl group is a key component of Fusarium trichothecene phytotoxicity (PubMed:10583973).  A second hydroxyl group is added to C-15 by the trichothecene C-15 hydroxylase TRI11, producing 15-decalonectrin, which is then acetylated by TRI3, producing calonectrin (PubMed:9435078, PubMed:8593041).  A third hydroxyl group is added at C-4 by the cytochrome P450 monooxygenase TRI13, converting calonectrin to 3,15-diacetoxyspirpenol, which is subsequently acetylated by the acetyltransferase TRI7 (PubMed:12135578, PubMed:11352533).  A fourth hydroxyl group is added to C-8 by the cytochrome P450 monooxygenase TRI1, followed by the addition of an isovaleryl moiety by TRI16 (PubMed:12620849, PubMed:14532047).  Finally, the acetyl group is removed from the C-3 position by the trichothecene C-3 esterase TRI8 to produce T-2 toxin (PubMed:12039755).
What are the official names of this protein?
Trichothecene C-3 esterase, Core trichothecene cluster (CTC) protein 8.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
Protein: IF1_SHIF8
Sequence: MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRSR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH1_ALKCK
Sequence: MSIQLPRGTQDILPDDAAIWQYIEQVAKETCETYHYQEIRTPIFEHTEIFSRGVGDTTDIVQKEMYTFSDRGGRSLTLRPEGTAAVVRSYVNHKLYASPAQPTKLYYTGPMFRYERPQAGRMRQFVQFGVEALGSASPQLDAEVLALLIAICKKLGLVNLKLVINSLGDSESRQAHREALIAHFKPSIDEFCSDCQMRLEKNPLRILDCKKDREHPLMATAPSILDYLNEESRAYFQSLKETLDLLNIPYVVDPTLVRGLDYYNHTAFELLSTAPGFGAITTLCGGGRYNGLVQEFGGPETPGIGFAFSIERFILAMKAENVDLPVPQSLDAYVVTLGDEASRLGPQLLQRLRDGGIRADKDYLGKKMKAQLKAADRYQASYTIIIGEDEIAKQQALVKQMATGEQTVVAISDLTSFLQEQIRGGN
What are the official names of this protein?
Histidine--tRNA ligase 1, Histidyl-tRNA synthetase 1, HisRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GREA_BAUCH
Sequence: MNQIPMTLRGAEQLREELNYLKNVRRPEIIRNIAEAREYGDLKENAEYHAAREQQGFCEGRIQEIESKLSHAQIIDVTKLFPSGKVVFGVTVSVQNLNINEEQTYRIVGDDEANFKHNLISISSPIARGLIGKKKGDIVLIKTPRGEVKYQILKIEYL
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: ATPB_LEPVR
Sequence: MRINLNPANAGLDLDVSIGENKNLGRIAQIIGPVLDVAFPPGKMPNIYNALVVKGRDTLGQEINVTCEVQQLLGNNRVRAVAMSATEGLKRGMDVVDMGNPLSVPVGGATLGRIFNVLGEPVDNLGPVDNRTKAPIHKSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEQNLAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGTLQERITSTKKGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQQVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFKLILSGEFDSLPEQAFYLVGNIDEATAKATNLEMESKLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: YPEA_SHIBS
Sequence: MEIRVFRQEDFEEVITLWERCDLLRPWNDPEMDIERKMNHDVSLFLVAEVNGEVVGTVMGGYDGHRGSAYYLGVHPEFRGRGIANALLNRLEKKLIARGCPKIQINVPEDNDMVLGMYERLGYEHADMLSLGKRLIEDEEY
What are the official names of this protein?
Acetyltransferase YpeA.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. YpeA subfamily.
Protein: RLMN_BURL3
Sequence: MTSETTVNLLDFDAEGLVAYCGSLGEKPFRAKQLQRWIHQYNAGDFDGMTDLAKSLREKLKGRASIGMPEIASDHVSTDGTRKWLIDVGNGNAVETVFIPEETRGTLCVSSQAGCAVNCRFCSTGKQGFSRNLSTAEIIGQLRMAEFALRASLGRAPGPNGKAERVVTNVVMMGMGEPLLNYSAVVPAMRLMLDDNAYGLSRRRVTLSTSGVVPMMDRLGAELPVALAVSLHAPNDPLRDELVPLNKKYPLRELMAACQRYLKVAPRDFITFEYCMLDGVNDTEAHARELLAVTRDVPCKFNLIPFNPFPESGLIRSKPEQIKRFAQVLIDAGVVTTVRKTRGDDIDAACGQLAGAVKDRTRLAERTGAAGKIIEVRAI
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCX10_CENEX
Sequence: KDGYLVEVTGCKKSCYKLGENKFCNRECKMKHRGGSYGYCYFFGCYCEGLAESTPTWPLPNKSCGKK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Neurotoxin Cex10.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPA_FRAT1
Sequence: MQLSPSEISGLIKQRIEKFDNSVELKSEGTIVSVADGIVTIYGLNDVAAGEMIKLPGDVYGLALNLNTDSVGAVVLGDYEHIKEGDKAYCTGRILEVPVGEALLGRVVDALGNPIDGKGEVATDLTSPIEKIAPGVIWRKSVDQALQTGIKSIDSMVPIGRGQRELIIGDRQIGKTAIAVDTIINQKGTGVKCIYVAIGQKASTIANIVRQLEEHGAMEHAIIVAATASDSAALQYIAPYAGCSMGEYFRDRGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNEEYVEKFTNGEVKGKTGSLTALPIIETQAGDISAFVPTNVISITDGQIFLETDLFNSGLRPAINPGNSVSRVGGAAQTKIIKKLGGGIRLALAQYRELEAFSQFASDLDEATRAQLNRGQRVTELLKQKQFSTLSVALMALSLYAADNGYLDNLEVSEVIPFESALHALAETKYSDVIAEINETGKYDADIADKLKIIVEDCKANQAW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SEC9_ASHGO
Sequence: MGFKKFFGIRPPEEDTPERNRDLLTEEGIATKNPNSFRKEKFAAYGKFAAANAQDHVYAPAGYEQYARPGAGADKDELESLNRAATDAGDIGNTSRVGQPQQRDPYAVNDNYNPYANGTARDPYATAQPYARQAPVRQAGPRHAAGTPYGSAAVPQGGPGNPYGGSTAGAGTGRNPYQKNMNATVYPPAAGKTANPYASMAQDPYGKGEQRGIAGGPVAMPVPMQPRPQAAAETPRPQAAAEKRAPAVDVDDLNAVIEPTNEDDDLNNSIHEGNEGLNGQGQAPRRGFQTFEELQREQEMKQQMEEDEEVDEIKQQIRFTKQSSVASTRNTLKMAQDAELAGMNSLGMLGHQSEKLNNVERNLNLMKVQNRVAEDKVAELKRLNRNILAVHVGNPFTSKRKVREAEERIKNQRMQDKMQQEETTTQLMSSTNRIENALNDERHSVRERYQRDQALERAKKYQFENDEEDDEMEFEIDRNLDKIGQVSGRLKKLAIAAGQEIDSQQSRIKRIEEDADDMDIRIHLNTSRLTNIR
What are the official names of this protein?
Protein transport protein SEC9.
What is the protein family that this protein belongs to?
Belongs to the SNAP-25 family.
Protein: CISY_ECOL6
Sequence: MADTKAKLTLNGDTAVELDVLKGTLGQDVIDIRTLGSKGVFTFDPGFTSTASCESKITFIDGDEGILLHRGFPIDQLATDSNYLEVCYILLNGEKPTQEQYDEFKTTVTRHTMIHEQITRLFHAFRRDSHPMAVMCGITGALAAFYHDSLDVNNPRHREIAAFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAGNFLNMMFSTPCEPYEVNPILERAMDRILILHADHEQNASTSTVRTAGSSGANPFACIAAGIASLWGPAHGGANEAALKMLEEISSVKHIPEFVRRAKDKNDSFRLMGFGHRVYKNYDPRATVMRETCHEVLKELGTKDDLLEVAMELENIALNDPYFIEKKLYPNVDFYSGIILKAMGIPSSMFTVIFAMARTVGWIAHWSEMHSDGMKIARPRQLYTGYEKRDFKSDIKR
What are the official names of this protein?
Citrate synthase.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
Protein: RS17_CUPMC
Sequence: MTEAAKTETSLRRTLVGRVVSDKMDKTVTVLIENRVKHPLYGKYVLRSKKYHAHDEANQYKEGDKVEIQETRPLSRTKSWVVSRLVEAARVI
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: LGT_CHLTE
Sequence: MIDFTTWWQHLPSQMNPVIFSIDGIAIRWYGTMYIVAFAIVYLLSKYRISNEKLPFDKTFPGDALTWAMGGVLIGGRIGYILFYGFDWFLQDPVGTLIPIKFGNGSCAFSGINGMSFHGGLIGVAIALWLFTRTHKVDFLKTVDLFIPALPLGYTFGRLGNFINGELYGRVTTSAIGMYFPAAPTVALRHPSQLYEAFFEGIVLFIILWTIRKKAPWPGYLSGLYLIGYGTVRFFIEFFREPDAQLGFVFLNFSMGQVLCFLMIAAGIGILVWSKQRAENADVMMGGKR
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNLJ_BUCBP
Sequence: MKDIKNYILKLQDEIRYHAYLYHTLNSPKISDEKYDFLVIELQRLEKKCKYSVRFKDSPTQSVGSENLPEFKKFSHITPMLSLNNVFIKNDFLKFYKKIVNNITVEKIFFCSELKFDGVAINLIYINGLLFRAVTRGNGYEGEDVTSNVNMISSVPKKLIGIDIPETLEVRGEIFMLKSDFKKLNVRLTKFKKKLFSNSRNAASGSLRHKNAKVTELRSLTFYCYGCGYCSYENFTDSHFLRLKKLKSWGFPISDYNFLHSSYDEILRFYNFIQNERYFLNFNIDGIVIKVDSICLQKSLSTTSKAPRWAVAYKFSDKIKITTIMNILYQVGRTGVITPVAQVTPIYISGVLIKKVSLHNFNEIRRLNLNIGDSVFIKRSGDVIPHIIEVASKCKLQRNEDISIPKFCPECGSKLKVDSFSNIKIRCMAGLKCLSQFKKLLHYFCSKKGLNILGLGPKIIDKLVDLGYVSDLSDIFDLNVSLLTKVENIGIIKSQNIIRSINNSKNVSFSKFLCSLGIFEVGSIVARSISNYFFTLDKFMNSSKEEFLLINGIGVNIADNLYNFINDEFNKNIIFKLSKKLNISSDINAIIDNNNTLFRKKIVFSGSFSNFSRSKIIELSKKLGIIVVSSVSKSVDYIIIGKKPGRKLIKAKKFSIPGIYEKEFLNIINVYL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: PESC_LEIMA
Sequence: MVHKKQAWAKRVKKERFKKKFLTRMQATRLLQMESVQFRRLCILKGIYPRALNRSKQKQSGNEKQYYLAREIKWLVRDQIAEKMMAYRAWEKKVKRAEAMGRSEDLKVLQTSRVKPRHSLVATIKERYPYFIDAIRDVDDAMSMIHLYAFLSPEIKSDTTIEIHHSLTSGLSERAKEVCERWDRYVARARVLTKGFISIKGYYYEAIVKGERVRWLCPHEYAHRFPPGIQQYVMLSFLEFYLEMMKFVLFKLESDLARDEADRLAAEDEEGVTRANAEDFANGAALAVLDVGANQAQAKAVKEAESKRSLMEEELHKVRELFRGLTFFISREVPAKHFALVINACGGRVATDYVPSNITHVVVDRPALPPGMKKHDQLEYVQPQYIFDCLNARLVLPVTGYRIGEELPPHVSPFSVSITNSAEDNAAVVQVKKDHPRIVGYVPARVHEIRKLINPSYSAVDPEGKVAHLEDEYSDEESHVAVPEMDMEDDVSLSGDELAEARRKPAWQEEEVTEEVQRPKLSAFKVKKQREMNLMNAPTNEVVARRRQALRKAQEKSRQTETSEARLQRKMSEVKRQEAATRKMQLQVARKKAARFYKMVSGVVQGTAKKVATLEAKAKHIAEGKLRKTEDGKGLVNKRLEARRQRAEAKGKKLKERKAGNPYKKLPKWVQ
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Pescadillo homolog.
What is the protein family that this protein belongs to?
Belongs to the pescadillo family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: RLUD_BUCAP
Sequence: MEKKELSACVPFMGFSGKRLDQILSKLFMQYSRSCLKKWIIMNNVYINGKIENQPDKKILGGEKITIYSTDEKLPINLPQNIALNTIYEDSNILIINKPPGLVVHPGAGNQDGTILNALLYRYTNISSIPRCGIIHRLDKDTSGLMVIAKTIFSYNKLVTLLKKRKIIRKYQGIIKGNMISGGIVNYPIMRHPFKRICMTTDSLGKKSITHYKIINRFKFHTHVSFRLETGRTHQIRVHMLHIGYPLLGDPLYGGIDYGCNYFQENRNIYRKFNLFRQALHADYIEFIHPFTQKVMSWSASLPQDMKDILLYLKK
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase D, 23S rRNA pseudouridine(1911/1915/1917) synthase, rRNA pseudouridylate synthase D, rRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: ATPD_BREBN
Sequence: MSSAVGKRYARALFEVASERSKIDQVEADLGAIVEAVEGNEDLKKIMLHPHIAADAKATLADELFKSHVGEEAFNFLNVLIENGREVDLVDIYRSFVQLANEARGFADAIVTSAKPLSTEEQNELAEKFGQTLNKKLRMTAVVDPAILGGVIIKIGDRLYDGSLKTKLETFAQKA
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL7_SHESW
Sequence: MSITKDQILEAFAAMSVMEVVELIEAMEEKFGVSAAAAVVSGGGEAAAAVEEQTEFNVILTAHGDNKVAVIKAIRGATGLGLKEAKAMSEAAPVAVKEGVSKEEAEALKKELVEAGASVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RSMG_LEIXX
Sequence: MTDSVELEPAAAAQLFGDRLPIARTFTANLASQGEERGLIGPLELPRLWSRHILNSAIVAPLLRPGVVGDVGSGAGLPGLVLAIARPDVSFVLIEPMDRRVIWLNEQVAELGLLNVDIVRARAEDAKLAKPLDQVTARAVSAFRKLLPLTAPLLRDGGELVLMKGAAAQAEIDGAAKEISKFKVRGAEVIVLGEGVLDEVTRVIRATVR
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 518 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_SALDC
Sequence: MSCPVIELTQQLIRRPSLSPDDAGCQALMIERLRKIGFTIEHMDFGDTQNFWAWRGRGETLAFAGHTDVVPAGDVDRWINPPFEPTIRDGMLFGRGAADMKGSLAAMVVAAERFVAQHPHHRGRLAFLITSDEEASAKNGTVKVVEALMARNERLDYCLVGEPSSTEIVGDVVKNGRRGSLTCNLTIHGVQGHVAYPHLADNPVHRAAPFLNELVAIEWDRGNDFFPATSMQVANIQAGTGSNNVIPGELFVQFNFRFSTELTDEMIKERVHALLEKHQLRYTVDWWLSGQPFLTARGKLVDAVVNAIEHYNEIKPQLLTTGGTSDGRFIARMGAQVVELGPVNATIHKINECVNAADLQLLARMYQRIMEQLVA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: CLPX_LEPBL
Sequence: MAKKTPGTNGKQKLFCSFCGKEQDAVKRLVAGPGVYICDECISLCNEIIAEDHEHSHEKSEVFSEIPNPVDIKSILDQYVIGQDHAKKALSVAVYNHYKRVNLKEKKSDVEIEKSNILLIGPTGSGKTLLAQTLARIIKVPFAIVDATALTEAGYVGEDVENIILKLIQNAENDIKKAEIGIIYIDEVDKIARKSDSASITRDVSGEGVQQALLKIIEGTIANVPPQGGRKHPHQEYLQVDTKNILFILGGAFVDLPNIIKSRTGVKTIGFGSEEQRIQAENKDTLMEQVIPEDLIKFGLIPEFIGRLPIVATLQELNVDMLKQIFREPKNSVLKQYTRLLELENVKLTFHEDAIDKIAELAIKRESGARGLRAIVENIMLDLMFDIPSRKDIEEVIITAEVITDRVTPTLILKKESKIA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: NDUS3_BETVU
Sequence: MDNQFIFKYSWETLPKKWVKKIEKSEHGNRFDTNTDYLFQLLCFLKLHTYTRFQVLIDICGVDYPSRKRRFEVVYNLLSTRYNSRIRLQTCADEVTRISLVVSLFPSAGWWEREVWDMFGVSFINHPDLRRILTDYGFEGHPLRKDFPLSGYVEVRYDDPEKRVVSEPIEMTQEFRYFDFASPWEQRNGNEG
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, NADH dehydrogenase subunit 9.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: VTA1_SCHPO
Sequence: MIQIDTIPKELQSIQPFVRRFNELEAHNPVIAYWSLYWAAQMALSSSHGVSNECKDFLLSLIEHLEDLRKNLGENENVSDETSAKAYVESFSLEVLVQAERNSKNGKPDVQAYLAARDFLELSRIWGPPTEQITKSIKFCKLRALQVANPQRKAKTPSNHATEELQQSSTNSTTLPTQEAAVETNASASHETSFALPTTSPAASLSISPTKSAAVSSEPNVEADVKSLSSTPAAPQLNSPSHSYEPTTFPSTTSITENLPTIDPTRSTRSSSHIQSLSPESKQTSDGHRPPSPTSITTTSTSIDPSVAFSSKSTLATTRTNAPLSRPSQPTKASPLNKFSALEAIQSARSHARYAYSALDYEDTTTAIHHLKSALKLLEEEEQGNHTAD
What is the function of this protein?
Has a role in the formation of the multivesicular body (MVB).  Required for the sorting of lipids to form intralumenal vesicles and for fluid-phase transport to the vacuole.  Required for sorting several plasma membrane proteins into the MVB (By similarity).
What are the official names of this protein?
Vacuolar protein sorting-associated protein vts1, VPS20-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the VTA1 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein.
Protein: KASA_MYCTU
Sequence: MSQPSTANGGFPSVVVTAVTATTSISPDIESTWKGLLAGESGIHALEDEFVTKWDLAVKIGGHLKDPVDSHMGRLDMRRMSYVQRMGKLLGGQLWESAGSPEVDPDRFAVVVGTGLGGAERIVESYDLMNAGGPRKVSPLAVQMIMPNGAAAVIGLQLGARAGVMTPVSACSSGSEAIAHAWRQIVMGDADVAVCGGVEGPIEALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFVFGEAGALMLIETEEHAKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLELAGLSPADIDHVNAHGTATPIGDAAEANAIRVAGCDQAAVYAPKSALGHSIGAVGALESVLTVLTLRDGVIPPTLNYETPDPEIDLDVVAGEPRYGDYRYAVNNSFGFGGHNVALAFGRY
What is the function of this protein?
Part of the mycobacterial fatty acid elongation system FAS-II, which is involved in mycolic acid biosynthesis.  Catalyzes the elongation of long chain acyl-ACP substrates by the addition of two carbons from malonyl-ACP to an acyl acceptor (PubMed:11600501, PubMed:12023885, PubMed:12464486, PubMed:16873379, PubMed:22017312, PubMed:24108128).  Involved in the initial extension of the mycolate chain and forms monounsaturated fatty acids that averaged 40 carbons in length (PubMed:12464486).
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] synthase 1, Beta-ketoacyl-ACP synthase 1, KAS 1, Beta-ketoacyl-acyl carrier protein synthase KasA, Meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase I.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2894_PSYIN
Sequence: MKLIVISGRSGSGKTIALHVLEDLGYNCIDGVPFQLLAQLIDTVDPKNNKVAISLDIRNLPTDASQIQTLLSSLQQKVEVEIIYLDAISAELIRRYSETRRLHPLSKNKLSLSQALELENELLEPIHKRAALSIDTTTLSIHNLNERLKIHLQGSTKSNLLIIFQSFGFKNIHPDDADYIFDVRFLPNPHWEPTLQKYTGKDQPVKAFLNGHLVVKQTINQIENLFHSWLPYLEENNRNYVTIAIGCTGGKHRSVYVAEQLAAQFKQKYQVQIEHKGLKDQL
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Ping_2894.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: RL2_SHEPC
Sequence: MAVIKCKPTSPGRRHVVKVVNTDLHKGKPFAGLLAKKSKSGGRNNTGRITVRHVGGGHKQHYRLIDFKRDKDGIPAKIERLEYDPNRTANIALVLYADGERRYILAAKGMQAGDKIQSGVEAEIKTGNAMPLRNIPVGSVVHAVEMKPGKGAQIARSAGAYVQVVARDGAYATLRLRSGEMRKVPVDCRATFGEVGNAEHMLRQLGKAGAKRWRGIRPTVRGVAMNPVDHPHGGGEGRTSGGRHPVTPWGVPTKGYKTRSNKRTDKYIVRRRNK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.