PharMolix/UniProtQA huggingface dataset:
Protein: NUOI_ACIAC
Sequence: MAAVAAATTSFSFKDFFKSFMLVELVKGMALTGRYAFRRKVTVQFPEEKTPLSPRFRGLHALRRYENGEERCIACKLCEAVCPALAITIESDVRADGSRRTTRYDIDLTKCIFCGFCEESCPVDSIVETQILEYHGEKRGDLYFTKDMLLAVGDRYEAEIAAAKAADAKYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PYRC_GEODF
Sequence: MNIFIKGGRVIDPSQNIDETLDLLVVAGRIKELGKGLKAPADAEVIDAAGLLVTPGLIDMHVHLRDPGLEYKEDVITGTMAAAAGGFTSVACMPNTKPVNDNKAITSYIVNKAKAEALVNVFPVGAITQGSKGENLAEMGELKEAGCVAVSDDGRPVVNAELMRRALEYAKGMGVMVIAHSEELALVGEGVMNEGFTATELGLKGIPWAAEDVAVARDVYLAEFTNSPIHIAHISTKGSVRIIRDAKARGVQVTCETAPHYFSLTDDAVRGYETNAKMNPPLREAEDVAAIKTGLADGTIDAIATDHAPHHLDEKDVEFNVALNGIIGLETSLPLSLKLVEEKVLDMKTLVEKMAVRPAQILGLDRGTLKTGAPADVTIIDPKAEWVVEAEKLASKSKNSPFLGRKMTGAAAYTIVDGKVVHKRD
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: PG035_VACCC
Sequence: MRTLLIRYILWRNDNDQTYYNDDFKKLMLLDELVDDGDVCTLIKNMRMTLSDGPLLDRLNQPVNNIEDAKRMIAISAKVARDIGERSEIRWEESFTILFRMIETYFDDLMIDLYGEK
What is the function of this protein?
Bcl-2-like protein which contributes to virulence by preventing host NF-kappa-B activation in response to pro-inflammatory stimuli such as TNF-alpha or IL1B.
What are the official names of this protein?
Protein OPG035, Protein N1.
What is the protein family that this protein belongs to?
Belongs to the poxviridae OPG035 family.
Protein: RUVC_SALPA
Sequence: MSIILGIDPGSRITGYGVIRQVGRQLTYLGSGCIRTKVDDLPSRLKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALKLGQARGVAIVAAVNQELPVFEYAARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHVSQNAMQMSESRLNLARGRLR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: SUFS_ECO27
Sequence: MTFSVDKVRADFPVLSREVNGLPLAYLDSAASAQKPSQVIDAEAEFYRHGYAAVHRGIHTLSAQATEKMENVRKRASLFINARSAEELVFVRGTTEGINLVANSWGNSNVRAGDNIIISQMEHHANIVPWQMLCARVGAELRVIPLNPDGTLQLETLPTLFDEKTRLLAITHVSNVLGTENPLAEMITLAHQHGAKVLVDGAQAVMHHPVDVQALDCDFYVFSGHKLYGPTGIGILYVKEALLQEMPPWEGGGSMIATVSLSEGTTWTKAPWRFEAGTPNTGGIIGLGAALEYVSALGLNNIAEYEQNLMHYALSQLAAVPDLTLYGPPDRLGVIAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAYYNVPAMCRASLAMYNTHEEVDRLVTGLQRIHRLLG
What is the function of this protein?
Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation.  Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine.  Selenocysteine lyase activity is however unsure in vivo.
What are the official names of this protein?
Cysteine desulfurase, Selenocysteine beta-lyase, SCL, Selenocysteine lyase, Selenocysteine reductase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS3_SYNFM
Sequence: MTLDPDFSKNDGLLPVIVQSADDDKVLMLAYMNELAWHRTLETGKAHYWSRSRRKLWQKGEESGNVQTIREILLDCDLDTILLKVVQTGGAACHDGYESCFYRRYADGKLEVVGKRVFDPKEVYKK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_HAEIE
Sequence: MTQTFADQKRKTVETAEFTEDGRYKRKVRSFVLRTGRLSEFQKNMMNDNWGTLGLDYQTEPFDFAKIYGNDNPVVLEIGFGMGKSLVDMAFANPDKNYLGIEVHTPGVGACIAYAVEKGGTNLRVICHDATEILRDSIADGALGGLQLFFPDPWHKAKHHKRRIVQPHFVAQVVQKLAGNGFIHMATDWENYAEQMLEVLSANTDLVNTSKNGDYIPRPDFRPLTKFEARGHRLGHGVWDLYFVKK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: AMOL2_HUMAN
Sequence: MRTLEDSSGTVLHRLIQEQLRYGNLTETRTLLAIQQQALRGGAGTGGTGSPQASLEILAPEDSQVLQQATRQEPQGQEHQGGENHLAENTLYRLCPQPSKGEELPTYEEAKAHSQYYAAQQAGTRPHAGDRDPRGAPGGSRRQDEALRELRHGHVRSLSERLLQLSLERNGARAPSHMSSSHSFPQLARNQQGPPLRGPPAEGPESRGPPPQYPHVVLAHETTTAVTDPRYRARGSPHFQHAEVRILQAQVPPVFLQQQQQYQYLQQSQEHPPPPHPAALGHGPLSSLSPPAVEGPVSAQASSATSGSAHLAQMEAVLRENARLQRDNERLQRELESSAEKAGRIEKLESEIQRLSEAHESLTRASSKREALEKTMRNKMDSEMRRLQDFNRDLRERLESANRRLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQGRAARAEEELRKKQAYVEKVERLQQALGQLQAACEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGSGGSPELSALRLSEQLREKEEQILALEADMTKWEQKYLEERAMRQFAMDAAATAAAQRDTTLIRHSPQPSPSSSFNEGLLTGGHRHQEMESRLKVLHAQILEKDAVIKVLQQRSRRDPGKAIQGSLRPAKSVPSVFAAAAAGTQGWQGLSSSERQTADAPARLTTDRAPTEEPVVTAPPAAHAKHGSRDGSTQTEGPPDSTSTCLPPEPDSLLGCSSSQRAASLDSVATSRVQDLSDMVEILI
What is the function of this protein?
Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites.  Required for proper architecture of actin filaments.  Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus.  Participates in angiogenesis.  May play a role in the polarity, proliferation and migration of endothelial cells.  Selectively promotes FGF-induced MAPK activation through SRC.
What are the official names of this protein?
Angiomotin-like protein 2, Leman coiled-coil protein, LCCP.
What is the protein family that this protein belongs to?
Belongs to the angiomotin family.
What are the subcellular locations of this protein?
Recycling endosome.
Protein: AB46G_ORYSJ
Sequence: MDDDVDAGEIYAVDRQREEGSASAAAFSRSPSTGRVDDDDDDLLTYGRSARRMAALPAPAMPEGTELRRPVGGDVVGDDDYLRFLYKFKELFDRVGIKLPTIEVRYKNLNVEAESYVGSRGLPTILNTYANILKGLANTLHMTTRSKQKISVLHNASGIIKPHRMTLLLGSPGSGKTSLLLALAGTLPSTVKVSGMITYNGHTMDKFIPQRSAAYVSQHDLHMAELTVRETINFSAKCQGVGHHYDLFLELLRREEEENITPDPETDIYLKAATTGEEKAEIVTNHILKILRLDICADTIVGDNMLRGISGGQKRCLDAHTAPNVDSAAEMLVTLGRALFMDEISNGLDSSTTFQIVNTIQQTIHVLGGTAVIALLQPAPETYELFDDIILLSDGQVVYSGPRDHVLEFFKSLGFKCLERIGVADFLQEVTSRKDQKQYWIHGDDTYRYIPVTVIAEAFQCFHVGQAIRSELAIPFDNSKSHIAALKTSKHGVNLKKILKANIDREILLLKRKSFLYIFNALQLTLVAIIAMSVFIHTNMHHDSIENGRMYMGVQFFGTLAIMFKGLAEMGAALANLPVFFKQRDLLFYPAWTYSLPSWIIKTPISFLNTIIWVSITYYVIGFDPNIERCFRQFLVLFVMSEAICGLFRFIAALTRHPVVASTVSEFCILIVMVSSGFILSRDEVKKWLIWEYWTSPLMYALNALAVNEFLSPSWNEALPGFREPLGRLVLESRGVFPEAKWYWIGLGALLGYVLLFNILYTICLSILTLLKRNVREMSQETLQIKLENLTGYDQEPSSGGRVTNDKRYTEGGNNDEATSSNANHNSSPARKGSILPFVPVYMTFEDIRYSIDMPKALKVQGMAGSRLELLKDLSGSFRPGVLTALMGISGAGKTTLLDVLAGRKTSGHIHGNITVSGYPKKQETFSRVSGYCEQNDIHSPNLTVYESLMFSAWLRLPAEIDSMARKRFIDEFMELVELFPLKDALVGLLGLSGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRTVRNIVDMGRTVVCTIHQPSIDIFESFDELFLMKRGGEAIYVGPLGQHSCELIKYFESIEGVRKIKHGYNPSTWMLEVTCTLQEQITGVNFTQVYKNSELYRRNKNLIKELSTPHDGSSDLLFPTKYSQTFVIQCLACLWKQRLSYWRNPPYIAVNFFFTVVIALLFGTMFWGVGRKRQSQQALLSAMGSMYSTCFTLGVQNSSSVQPVVNIERTVFYRERASHMYSPLPYALGQVVVELPYIFLQTLIYGVIVYSMMGYEWTCTKFFWYMFFMYFTLSYFTFYGMMAAGLTPNYTMSSIVSTTFYAIWHLFSGFLIPKTRIPIWWRWYYWICPVAWTINGLVTSQFGDVDDKFDNGVRVSDFVESYFGYNLDLLWVAAMAVVSFAILFAILFGFSLKLFNFQKR
What is the function of this protein?
May be a general defense protein.
What are the official names of this protein?
ABC transporter G family member 46, OsABCG46, Pleiotropic drug resistance protein 21, OsPDR21.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL26_BRUPA
Sequence: MKQNQFVSSSARKARKAPFNAPSHIRRKLMSAPSTKDLRNKHGIRSIPIRIDDEVTVTRG
What are the official names of this protein?
60S ribosomal protein L26.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: LEXA_FRACC
Sequence: MTSQGRGTRRGGTRGNVRAFPEGPTDAGLTPRQRRVLEVIRAAVERRGYPPSVREIGEAVGLTSTSSVAHQLKVLEEKGYLRRDPNRPRAMEVLTVEHPRQRADVGAGATTVAGTIPIVGEAAPGTTEGSKSDAAYVPVLGRIAAGGPILAEQAVEDVFPLPREIVGEGTLFLLRVVGDSMINAAICDGDWVVVRQQPVADNGEIVAAMIDGEATVKRLRVRDGKIWLHPENSAFADIPGEDATILGRIVAVLRRV
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: WLIM1_ARATH
Sequence: MAFAGTTQKCMACDKTVYLVDKLTADNRVYHKACFRCHHCKGTLKLSNYNSFEGVLYCRPHFDQNFKRTGSLEKSFEGTPKIGKPDRPLEGERPAGTKVSNMFGGTREKCVGCDKTVYPIEKVSVNGTLYHKSCFKCTHGGCTISPSNYIAHEGKLYCKHHHIQLIKEKGNLSQLEGGGENAAKDKVVAA
What is the function of this protein?
Binds to actin filaments and promotes cross-linking into thick bundles.  Has an actin-stabilizing activity.  The actin regulatory activities are not regulated by pH and [Ca(2+)].
What are the official names of this protein?
LIM domain-containing protein WLIM1, Widely-expressed LIM protein 1, AtWLIM1.
Protein: RUBR2_CLOPE
Sequence: MKKFICDVCGYIYDPAVGDPDNGVEPGTEFKDIPDDWVCPLCGVDKSQFSETE
What is the function of this protein?
Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide.  Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.
What are the official names of this protein?
Rubredoxin-2, Rd 2.
What is the protein family that this protein belongs to?
Belongs to the rubredoxin family.
Protein: GNAO_RAT
Sequence: MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGVEYGDKERKADSKMVCDVVSRMEDTEPFSAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYPGSNTYEDAAAYIQTQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.  The G(o) protein function is not clear.  Stimulated by RGS14 (By similarity).
What are the official names of this protein?
Guanine nucleotide-binding protein G(o) subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(i/o/t/z) subfamily.
What are the subcellular locations of this protein?
Cell membrane. Membrane; Lipid-anchor.
Protein: SURE_VIBPA
Sequence: MELDSLNTKPLRILISNDDGVHAQGIHALADELRSIAEVIIVAPDRNRSGASNSLTLEQPLRVSEIAPNTYSVQGTPTDCVHFALNELMKDDLPDLVLSGINHGANLGDDVLYSGTVAAAMEGHFLGVQAIAFSLVGKRHFESAAKIARQLVEQHLAAPIPTNRLLNVNVPDLPLESLGEIEVTRLGARHHAENMIKQKDPRGHDIYWLGPPGKEQDAGEGTDFYAIEHGRVSITPLQVDLTAHESLRAMDSWLKEEK
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX16_MOUSE
Sequence: MIAPAVLRALRKNKTLRYGVPMLLLVVGGSFGLREFSQIRYDAVTIKIDPELEKKLKVNKITLESEYEKIKDSTFENWKNIRGPRPWEDPQLLQGRNPETLKPKTT
What is the function of this protein?
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase.  Promotes the insertion of copper into the active site of cytochrome c oxidase subunit II (MT-CO2/COX2).  Interacts specifically with newly synthesized MT-CO2/COX and its copper center-forming metallochaperones SCO1, SCO2 and COA6.  Probably facilitates MT-CO2/COX2 association with the MITRAC assembly intermediate containing MT-CO1/COX1, thereby participating in merging the MT-CO1/COX1 and MT-CO2/COX2 assembly lines.
What are the official names of this protein?
Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COX16 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RL21A_CANAL
Sequence: MGKSRGYRSGTRYAFQRDFKKHGAIPLSTYLKVYKVGDIVDIKANGSIQKGMPHKYYHGKTGIVYNVTKSSVGVIINKVVGNRYIEKRVNLRVEHVKHSACRQEFLNRVKSNAAKKREAKANGETVYLKRQAAKPRGSRIISTEGNIPQTLAPVAYETFI
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L21-A.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
Protein: CRCB_VIBVY
Sequence: MSQFAILGFIALGGAFGACSRYLVSELCVVLLGRGFPYGTLTVNVVGSFIMGLLIAAFESELLATEPWRQIIGLGFLGALTTFSTFSMDNVLLMQQGAFFKMGLNVVLNVTLSITAAWVGFQLLKS
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DEGPL_HALED
Sequence: MTRMTRHLALWMLLSLAILASQSAMAQKLPDFTSLVEEAAPAVVNISTSRTVETRNMPFGQFGGQELPEIFKHFFGERFGDQMPMPPGAQGHSEERRSLGSGFIISEDGYIMTNAHVVEGADEILVSLNDGRELKAELVGADTKTDVAVLKVDADNLPTLTLGDSEDLKVGQWVAAIGSPFGLDHSVTSGIISAINRTLPRDVYVPFIQTDVAINPGNSGGPLFNLDGEVIGINSQIFTRSGGYMGLSFAIPIDVAMDVADQLRNDGSVSRGWLGVMIQPVSRELADSFGMDKPQGALIADLDPDGPAARDGLKAGDVVLEVDGQTVDSSSALPRLIGRVSPGNDVELKVLRNGEHRNVTVTVGDWPDSQKGAGGSAGDTAPARLGLAVRPLEEGQHDQAIDNGVRVVEVDPTGVAAKAGIRAGDILVSIGEHAVESPEQLSELIGELPEDRAVPVRLYRSGHSYYVALRLAQK
What is the function of this protein?
Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions.
What are the official names of this protein?
Probable periplasmic serine endoprotease DegP-like, Protease Do.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RS27A_AERPE
Sequence: MAEKKELKTYVHKLYEVDYEKGVIKLKNRRCPRCGSIMAHHMKPVERWHCGKCGYTEFVTKKK
What are the official names of this protein?
30S ribosomal protein S27ae.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS31 family.
Protein: FBL9_ARATH
Sequence: MSSSSSSPFPQAMKNGEYRNWAELPPELTSSILLRLGAIEILQNAQRVCKSWRRVCQDPSMWRKIDIRIKENLVNSVELFYVIEPLCCRAVDLSQGGLLEINIDYLVNTSFLNYIADRSSNLRRLGVVDCAPVLSRGVVEAAMKLPLLEELDITYKSSIREQELKVVGQSCPNLRTLKLNCTGDVKCCDKVALAIAETMPGLRHLQLFRNGLSETGLNAILEGCPHLKNLGLHQCLNINIVGDIVK
What are the official names of this protein?
Putative F-box/LRR-repeat protein 9.
Protein: GCSH_SHEB2
Sequence: MSNIPTELKYASSHEWIRKEEDGSYTVGITEHAQELLGDMVFVELPEVGDTVTAGEDCAVAESVKAASDIYAPISGEVIAVNEALEDSPELVNSSAYGEGWFFRVMPSDESEVDALLDAEGYQAVIDED
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: NHR18_CAEEL
Sequence: MPAPLFLSGSCEVCGDKTSGRHFGVMSCRACAAFFRRAATWNLEKRICPNGTCHTSVNGKFNCKQCRLKKCLDVGMDTRRFQTDRDLISCSAISQSLATFLGRPEFILCCEPDRASVLKTTIDVTRLVNIARDMLQKPTNHVLPSNSLEQLATTLDNMRCVESNKEVKFIEKYGKVETLKSWEQGFLRVVEWFSNFSEFRELNERLKLEIVKSCWFSWTRLDKLSETANKQINKMLGKSQLMVGNGACMNMNNFEIDLSWCTNYSLEQLKYFFQTPNGKKNFQQSIQDMIDLNPSSIEVSYMLLHLSLEHAGKRLHGDALDATENLVQVQANNLHKYYVEKLKLANYSSRLTQLMRITRTLEADIRIRIEKKQIADVFNIMKIDFSHPEMFEAT
What is the function of this protein?
Orphan nuclear receptor.
What are the official names of this protein?
Nuclear hormone receptor family member nhr-18.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MSCL_PEDPA
Sequence: MLKEFKEFVSRGNVLDLAVGVIIGGAFTSIVKSLVNYLINPLIGLFIGGIDFSDWVLKVAGATFKFGSFINAVINFLIIAFVVFILVKLVNKFLPKKEEQEDDEAEAIENSEIYLKEIRDALVNNPELLSNLKNKEDSTK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y904_TREPA
Sequence: MNKNTQDKGTPAALQVFLLPQYNRYSAEMTRHVPLLCNLFSMSRYVLRHLTAQIILERMSAACVCLRRRRQSEFTDPTEKIGE
What are the official names of this protein?
Uncharacterized protein TP_0904.
Protein: MLTF_PSEE4
Sequence: MFAHTAFRQRCARWLFATGLFLMLGACVEKPSTLERVKEDGVLRVITRNSPATYFQDRNGETGFEYELVKRFADDLGVKLQIETADNLDELFDQLGKPSGPVLAAAGLVSSERRGAQARFSHPYLEVTPQVIYRNGRSRPTNAKGLVGKKIMVLKGSSHADQLAELKKQNPGLEYEESDAVEVVDLLRMVDEGQIDLTLVDSNELAMNQVYFPNVRVAFDLGDTRDQRWAVAAGDDNSLLNEINEFLDKSQKNGTLQRLKDRYYGHVDVLGYVGAYTFAQHLQQRLPKYEKHFKATSKVEQVDWRLLAAIGYQESMWQPEVTSKTGVRGLMMLTQRTAQAMGVSNRLDPKQSIQGGAKYFMVVKDQLDDSIKEPDRTWFALAAYNVGSGHLEDARTLAKREGLNPNKWLDVKKMLPRLSQKQWYSKTKYGYARGGEPVHFVANIRRYYDILTWVTQPQLEGQVAEGNLHVPGVNKDKPAEQSPQM
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: FHL3_MOUSE
Sequence: MSEAFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNECYCTAFSSQCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQPWHRECLVCTGCKTPLAGQQFTSRDDDPYCVACFGELFAPKCSSCKRPITGGSGGGEGAGLGGGKYVSFEDRHWHHSCFSCARCSTSLVGQGFVPDGDQVLCQGCSQAGP
What is the function of this protein?
Recruited by SOX15 to FOXK1 promoters where it acts as a transcriptional coactivator of FOXK1.
What are the official names of this protein?
Four and a half LIM domains protein 3, FHL-3, Skeletal muscle LIM-protein 2, SLIM-2.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: GPMI_CAMJJ
Sequence: MKQKCVLIITDGIGYNKNSKFNAFEAAKKPSYEKLFKEVPNSLLKTSGLAVGLPEGQMGNSEVGHMCIGSGRIIYQNLVRINKAIENKELEKNENLQKLLAKCKRVHIIGLYSDGGVHSMDTHFKAMLEICAKNGNEVFAHAITDGRDVNPKSGLNFIKDLKEFCENLGVHFATLCGRFYAMDRDKRWDRVKECYECLLGKAYKVPNLLEYLQKSYDENVTDEFIKAVQNENYKGMREEDGIIFINFRNDRMKQLVEVLNSKDFKEFEREKIFENLLTMSVYDDKFKLPVLFEKEKIENTLAQVISKAGLSQLHTAETEKYAHVTFFFNGGKEELLENETRVLIPSPKVKTYDEKPQMSAFEVCDAVKKGIEKGEDFIVVNFANGDMVGHTGDFNAAIKAVEAVDTCLGEIVECAKKHDYAFIITSDHGNCEAMQDEKGNLLTNHTTFDVFVFVQAKGVSKIKDNMGLSNIAASVLKILDLEIPKEMNEALF
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: DPOL1_METTH
Sequence: MEDYRMVLLDIDYVTVDEVPVIRLFGKDKSGGNEPIIAHDRSFRPYIYAIPTDLDECLRELEELELEKLEVKEMRDLGRPTEVIRIEFRHPQDVPKIRDRIRDLESVRDIREHDIPFYRRYLIDKSIVPMEELEFQGVEVDSAPSVTTDVRTVEVTGRVQSTGSGAHGLDILSFDIEVRNPHGMPDPEKDEIVMIGVAGNMGYESVISTAGDHLDFVEVVEDERELLERFAEIVIDKKPDILVGYNSDNFDFPYITRRAAILGAELDLGWDGSKIRTMRRGFANATAIKGTVHVDLYPVMRRYMNLDRYTLERVYQELFGEEKIDLPGDRLWEYWDRDELRDELFRYSLDDVVATHRIAEKILPLNLELTRLVGQPLFDISRMATGQQAEWFLVRKAYQYGELVPNKPSQSDFSSRRGRRAVGGYVKEPEKGLHENIVQFDFRSLYPSIIISKNISPDTLTDDEESECYVAPEYGYRFRKSPRGFVPSVIGEILSERVRIKEEMKGSDDPMERKILNVQQEALKRLANTMYGVYGYSRFRWYSMECAEAITAWGRDYIKKTIKTAEEFGFHTVYADTDGFYATYRG
What is the function of this protein?
In addition to polymerase activity, this DNA polymerase exhibits 3'-5' exonuclease activity.
What are the official names of this protein?
DNA polymerase PolB subunit 1.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.