PharMolix/UniProtQA huggingface dataset:
Protein: FEN1_PLAF7
Sequence: MGIKGLTKFIADAAPNAIKEIKIESLMGRIIAIDASMSLYQFIIAIRDSEQYGNLTNESGETTSHISGLMSRSIRLMENGLKPIYVFDGAPPELKGSELEKRGEKRQKAEELLKKAKEEGNLEEIKKQSGRTVRVTRKQNEEAKKLLTLMGIPIIEAPCEAESQCAFLTKYNLAHATATEDADALVFGTKILIRNLNANATSNQNKNKNNSKRGYILTEINLEQVLKGLNLTMDEFIDFCILCGCDYCDTIKGIGSKTAYNLIKEYNCIEKIIENIDQNKYQVPSNFRFQEARKSFINPNVLPKEDIKIDWNEPQIEELKHFLIKDYNFNELRVTNYINRLLKARKVTTQRRLDNFFTACTKKSTKLIVEETKKEQTLPARKGKKRPTAGDKNKQKAVKRKIEQANANGHHKMKEENKSVDNEKNEDGIKSVDNEKNEDGIKSVDDEKNLDDEKNLDDEKNKDDEKNKDDEKNKDDEKNKDDEKNKDDEKKSLDNFSSNLFDSDKESESGNIIKNEKQNMDDEKINDNLPSLFGDHSRIRHTENKDNISDINNNNNNNNSSSNNNNISNNHFNSVSSNSTFNSSTKLKSEDTLKSNSPLKEDSPNSYNNIKNNNHTININSQINNHKEPISNNNLNNINNSTEIKKKNTLFLLPFCPKDVTNVKKKKYTQRC
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: EF1A_PYRAE
Sequence: MPSIILPPKPTALQKPHINLAVVGHVDNGKSTLVGRLLYETGYVDEKALKEIEEMAKKIGKEDFAFAWILDRFKEERERGVTIEATHVGFETNKLFITIIDLPGHRDFVKNMIVGASQADAALFVISARPGEFEAAIGPQGQGREHLFLIRTLGVQQIVVAVNKMDVVNYDQKRYEQVKAEVSKLLKLLGYDPSKIHFIPVSAIKGDNIKTKSSNTPWYTGPTLLEVFDSFQPPQRPVDKPLRMPIQDVFTITGAGTVVVGRVETGVLKVGDRVVIVPPAKVGDVRSIETHHMKLEQAQPGDNIGVNVRGIAKEDVKRGDVLGKPDNVPTVAEEIVARIVVLWHPTAIGPGYAPVMHIHTATVPVQITELVSKLDPRTGQAVEQKPQFIKQGDVAIVKIKPLKPVVAEKFSDFPPLGRFALRDMGRTIAAGQILEVKPAQVQIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha, Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRAC_CLODI
Sequence: MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEENLDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAAIETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPGVGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLAHIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGEKFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFILK
What is the function of this protein?
Catalyzes the reversible interconversion of L- and D-proline.  Plays an important role in the regulation of intra- and extracellular amino acid pools, allowing the bacterium to profit from host precursors and enzymatic pathways.  Strong B-cell mitogen.
What are the official names of this protein?
Proline racemase, CdPRAC.
What is the protein family that this protein belongs to?
Belongs to the proline racemase family.
Protein: FOLD_AMOA5
Sequence: MAVILDGKQVAHFLRQSLAEQVQTLAKEGKPIPHLAIVLVGDDPASHTYVYNKVKACQEVGFQTTFIQEASHVQESTLLYLIHKLNEDTSIHGIIIQLPLPKHINAIKIIQAITPSKDVDGLHTFNYGRMACNLPTHIPATPLGILLLLEHYQIETAGKHCVIIGRGPTVGAPLSILMSRNAYPGNATVTLCHSYTQQLTNFTRQADILVVAVGKPGLITADMIKPSTTVIDVGITRIPDTTKKRGYRLKGDVAFEEVATLCNAITPVPGGVGPMTIAALLTNTLRAATNQVYNTPTS
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: PSBC_CUSEX
Sequence: MKTLYSLRRFYHVETLFNGTLALAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVIDTFPYFVSGVLHLISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGIGAFLLVLKALYFGGVYDTWAPGGGDVRKIANLTLSPSLIFGYLLKSPFGGEGWIVSVDDLEDIIGGHVWLGSICILGGIWHILTKPFAWARRAFVWSGEAYLSYSLGALSIFGFTACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLNRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLATSHFVLGFFFFIGHLWHAGRARAAAAGFEKGIDRDFEPVLSMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid membrane; Multi-pass membrane protein.
Protein: PDI22_ARATH
Sequence: MERKMYKSTVFPICCLLFALFDRGNALYGSSSPVLQLTPSNFKSKVLNSNGVVLVEFFAPWCGHCQSLTPTWEKVASTLKGIATVAAIDADAHKSVSQDYGVRGFPTIKVFVPGKPPIDYQGARDAKSISQFAIKQIKALLKDRLDGKTSGTKNGGGSSEKKKSEPSASVELNSSNFDELVTESKELWIVEFFAPWCGHCKKLAPEWKKAANNLKGKVKLGHVNCDAEQSIKSRFKVQGFPTILVFGSDKSSPVPYEGARSASAIESFALEQLESNAGPAEVTELTGPDVMEDKCGSAAICFVSFLPDILDSKAEGRNKYLEMLLSVADKFKKDPYGFVWVAAGKQPDLEKRVGVGGYGYPAMVALNAKKGAYAPLKSGFEVKHLKDFVKEAAKGGKGNLPIDGTMEIVKTEAWDGKDGEVVDADEFSLEDLMGNDDEASTESKDDL
What is the function of this protein?
Acts as a protein-folding catalyst that interacts with nascent polypeptides to catalyze the formation, isomerization, and reduction or oxidation of disulfide bonds.
What are the official names of this protein?
Protein disulfide-isomerase like 2-2, AtPDIL2-2, Protein disulfide-isomerase 10, PDI10, Protein disulfide-isomerase like 5-1, AtPDIL5-1.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: PURA_DESPS
Sequence: MSSVVVVGAQWGDEGKGKIVDLLTKYSDYIVRFQGGNNAGHTLVVDGKKFVFHIIPSGILYEEKTCMIGNGVILDPGVLLEEMASLKERGLEVKPNRLMISDNAHLIMPYHSQLDQAKESALSASNKIGTTGRGIGPCYMDKVGRVGIKAGDLLDEDLFREKLRCAIEEKNFILTKKFGAPAVDFDSVYRQFMDFAEQLSPYFGNVSVTLDEARRADKNILFEGAQGTQLDIDHGTYPFVTSSNTVAGNACAGSGFGPSHIDAVVGIVKAYTTRVGSGPFPTELFDEKGEELQNKGSEFGATTGRRRRCGWFDGVVANDAVRLNGLTGWALTKLDVLSGQKSIKMASSYDLNGKKLHAMPNNIKDAEALKPVYEEVPGWADEVDGICNYDDLPTEAKDYVRRIEDFTGVPANIVSVGPDRAQTMMLSNPFETKKCCK
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLD7A_PONAB
Sequence: DWHLDMQLTGKVVLSAAALLLVTVAYRLYKSRPAPAQRWGGNAQAEAKEEAQGSGQPAVQEASPGVLLTGPRRRRSSKGAEAPQGCSCENPRGPYVLVTGATSTDRKSQRKGSGEERGGQSSDSEQVPPCCRGQETRTAVSGNPDPPHLPRLGSEPNSSPAGLIAAADGSCAGGELSPPQDSKPPEHPGLGQLEPPHCHHPAPLQGSSDMNQSWVFTRVIGVNREEAGALEAASDVGLTLHQQEGAPNASYTFSSIARVRMEENFIQKVEGVEPRLKGKVYDYYVESTSQAIFQGRLAPRTAALTEVPSPRPPPRSLGTGAASGGQAGDTKGAAERAASPQPGPSPSTRGFSRKESLLQIAENPELQLQPDGFWLPAPPCPDPGALPGSGRSSQEPHVQLVAGTNFFHIPLTSASAPQVHLDLGNCYEVLTLAKRQNLEALKEAAYKVMSENYLQVLRSPDIYGCLSGAERELILQRRLQGRQYLVVADVSPKEDSGGLCCYDDELDVWRPLARLPPEAVSRGCAICSLFNYLFVVSGCQGPGHQPSSRVFCYNPLTGIWSEVCPLNQARPHCRLVALDGHLYAIGGECLNSVERYDPRLDRWDFAPPLPNDTFALAHTATACAKEIFVTGGSLRFLLFRFSAQEQRWWAGPAGGSKDRTAEMVAVNGFLYRFDLNRSLGIAVYRCSASTRLWYECATYRTPYPDAFQCAVVDNLIYCVGRRSTLCFLADSVSPRFVPKELRSFPAPQGTLLPTVLTLPTPDLPQTRV
What are the official names of this protein?
Kelch domain-containing protein 7A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: QUEA_CALS4
Sequence: MKRSEFYFDLPEELIAQEPLEDRASSRLMILDRRTGEIKHDIFKNITKYLKEGDCLVLNDTKVIPARLIGQREDSGGKVELLLLRRTSMNEWEVLVKPGKRAKVGKRVVFGNGELVAEIIDTTEAGGRIARFYYDGVFEEVLDRLGEMPVPPYIKKKLKDKNRYQTVYAKYEGSAAAPTAGLHFTEELLDEIRNMGVKTVFITLHVGLGTFRPVKEEIIENHKMHEEFYIVTEEAAKAINEARKNGGRIIAVGTTSTRTLETVADESGYIHPKSGWTDIFIYPGYKFKAIDGMITNFHLPESTLIMMVSAFAGKENIMRAYKVAIENKYRFFSFGDAMLII
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SBI_STAA9
Sequence: MKNKYISKLLVGAATITLATMISNGEAKASENTQQTSTKHQTTQNNYVTDQQKAFYQVLHLKGITEEQRNQYIKTLREHPERAQEVFSESLKDSKNPDRRVAQQNAFYNVLKNDNLTEQEKNNYIAQIKENPDRSQQVWVESVQSSKAKERQNIENADKAIKDFQDNKAPHDKSAAYEANSKLPKDLRDKNNRFVEKVSIEKAIVRHDERVKSANDAISKLNEKDSIENRRLAQREVNKAPMDVKEHLQKQLDALVAQKDAEKKVAPKVEAPQIQSPQIEKPKAESPKVEVPQIQSPKVEVPQSKLLGYYQSLKDSFNYGYKYLTDTYKSYKEKYDTAKYYYNTYYKYKGAIDQTVLTVLGSGSKSYIQPLKVDDKNGYLAKSYAQVRNYVTESINTGKVLYTFYQNPTLVKTAIKAQETASSIKNTLSNLLSFWK
What is the function of this protein?
Plays a role in the inhibition of both the innate and adaptive immune responses.  Possesses two N-terminal domains that bind the Fc region of IgG and two domains that form a tripartite complex with complement factors C3b and CFH.  By recruiting CFH and C3b, the secreted form acts as a potent complement inhibitor of the alternative pathway-mediated lysis.
What are the official names of this protein?
Immunoglobulin-binding protein Sbi.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin-binding protein Sbi family.
What are the subcellular locations of this protein?
Secreted. Cell membrane. Note=Occurs both extracellularly and associated with the cytoplasmic membrane where only the domains I and II are exposed to the extracellular media. Membrane association occurs via binding to lipoteichoic acid.
Protein: RRF_GEOUR
Sequence: MTKDVINNMSTHMDKTIDALRKEYQRVRTGRASTGLLDEIKVDFYGTPSPINQVATLAVPEPRTITLQPWDAKMIPVIEKAIMNANLGLTPANDGKVIRLNIPPLTEERRKDIVKQLKKLAEDAKVAVRNIRRDAIDELKKQEKDKKISEDDLKRAEKEVQDVTNSHVAKIDEVFVHKEKEVMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_ECOL5
Sequence: MDYTLTRIDPNGENDRYPLQKQEIVTDPLEQEVNKNVFMGKLNDMVNWGRKNSIWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADLMVVAGTCFTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFIPVDVYIPGCPPRPEAYMQALMLLQESIGKERRPLSWVVGDQGVYRANMQSERERKRGERIAVTNLRTPDEI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YTJA_ECOL5
Sequence: MFRWGIIFLVIALIAAALGFGGLAGTAAGAAKIVFVVGIILFLVSLFMGRKRP
What are the official names of this protein?
UPF0391 membrane protein YtjA.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HUTI_BURCJ
Sequence: MKPTVWHHLRLCPHGHPDETIDDAAIAVDETGTIAWLGALSALPHGYAHWRREDLHGAWVTPGLVDCHTHLVYGGTRADEFAQRLAGVSYEEIARQGGGIVSTVRATRAADETTLFVQAAARLQPLLAEGVTAIEIKSGYGLDLASERKMLRVARQLGERFPVTVHTTFLGAHALPPEYAGRADAYIDEVCDRMLPTLADEGLVDAVDVFCERIGFSLAQTERVFEAATRRGLPVKLHAEQLSNAGGTALAARYRALSADHLEFLDEAGIEAMKAAGTVAVLLPGAYYFIRETQLPPIELLRKHGVPIALATDHNPGTSPLESLLLTLNMGCTLFRMTVPEVLQGVTRHAAAALGRADRHGALEVGRQADFAVWSVGSLAELAYWIGRPLCEQVVRGGTTVFRRMNG
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_PSYIN
Sequence: MKKLAILGATGSIGDSTLSVCRSNPELYQITLLAASSSVDKMLALCREFTPLYVSMSSEISAKKLRGLLKRNNLSCHVLDDEQRLLELLASDHVDSVMAAIVGAAGLKTTLAAVDAGKEVFLANKEALVMSGALFIDAVKKSGAKLWPVDSEHNAIYQALSPKLQNTIGACDLSGEGVSKILLTGSGGPFLEKPLAEFAAITPAQAVKHPNWSMGKKISIDSATMMNKGLEYIEARWLFNANKEQLQIIIHPQSVIHSMVQYKDGSVIAQMGNPNMRIPIAYVLGGEQRIESGTDFLDFFAAPDFSFTAPDFDRYPCLKLAIDACFEGQQSTTILNAANEIAVEAFLNQTIKFTQISQLVERVLNQHESAAIESVEHLLEIDTEARLSASEIIKRDYLC
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: KCY_HALLT
Sequence: MLITVSGPPGSGKSTNAAGLADRLGLDHVSGGDIFREMAAERDMTPVEFNEFAEEDPQIDRDLDRRLHEIATTRDDLVLESRLAGWLSADHADFRFWFDAPVSTRAERIAEREEKPVDRAKAETERREASEKKRYREYYDIDIGDLSIYDAAYNTARWGPERFIDVLVATIDAYDPATDEGKAPIEGVSYDF
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_AROAE
Sequence: MGMSEIAKAAQKDKAIGGADRDSHTPMMQQYLRIKAQHPDTLLFYRMGDFYELFFDDAEKAARLLDITLTTRGQSAGTPIRMAGVPFHAVEQYLARLVKLGESVVIAEQVGEPGATKGPMERAVSRIVTPGTLTDAALLDDRIDSLLLAATLHRGVLGLAWLNLANGDLRVMECPAEQLQAQFERLRPAEVLVPDGLALPLVESLSPVLRRLADWQFDAGNGERLLTAHFGTRDLAGFDAEGLPVALAAAAALFEYARSTQRQSLEHVTGLRVEREAEYLRLDAATRRNLELTETLRGEASPTLFSLLDSCITSMGSRWLRHALHHPLRDRGVAAQRHGAVGELAGSDAGAPADIGDARMLGAVRAALRGVADVDRITARIALRSARPRDLAALSDSLARLPQLHAALGTPQAPLLCDLLAAIAVPDNALDLLVRAVAAEPAAAVRDGGVIAPGFDAELDELRGIQSNCGEFLLALEVRERERSGIATLKVEFNKVHGFYIEVSHANTGKVPDDYRRRQTLKNAERYITPELKAFEDKALSAQERALAREKLLYEALLEALAAHIPALQRIARALACLDGLGAFAEAAVRHSYVCPQFSAQPGVDIIGGRHPVVERQVEDFISNNCRLAPTRRMLLITGPNMGGKSTFMRQVALIALLAHVGAFVPARSARLGPLDAIFTRIGASDDLASGRSTFMVEMTEASAILHGATEQSLVLMDEIGRGTSTFDGLALAFAIARHLLEKNRCLTLFATHYFELTRLNGDYPECANVHLDAVEHAHRIVFLHAVEDGPASQSYGIEVAALAGIPGSVVREAKRRLRALENREVGNGPQADLFAALPDREPATPSHPALTALAELDPDTLSPREALERLYALKRMTA
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RNZ_METVS
Sequence: MKLTFLGTGAAVPTKYRSHPSVALKFDGEIFLFDCGENTQRQIIFTDVSPMKINNIFISHLHGDHILGIPGLLQSIAFQGRKKPLNIYGPPETKEMIKNMLKIGYHSIDYPINIHEASIESPEMIIASSNNSNGNNYEVYTFPVKHSVPSISYLFKQIKKPQMDIKKAETLGIEIGPDLKKLKDGFSIQLKNGKVITPKDVTIPPKKGYCIGYSGDTIPIDEFGKFLKYHGCNVLIHEATFDSSMQKNAVDTMHSTILDALDILEKSGARTLIATHISARYDDIMSFERDIVKFKEKNPEIEILIAEDFLEYVLK
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: TAOK3_HUMAN
Sequence: MRKGVLKDPEIADLFYKDDPEELFIGLHEIGHGSFGAVYFATNAHTSEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQLKHPNTIEYKGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALHGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFVRRDRPLRVLIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLNREMDSLGSNHSIPSMSVSTGSQSSSVNSMQEVMDESSSELVMMHDDESTINSSSSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYKRMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQYKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQNIREELNKKRTQKEMEHAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYKALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHERELQKLEQRVSLRRAHLEQKIEEELAALQKERSERIKNLLERQEREIETFDMESLRMGFGNLVTLDFPKEDYR
What is the function of this protein?
Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade.  Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade.  In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases.  Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF).
What are the official names of this protein?
Serine/threonine-protein kinase TAO3, Cutaneous T-cell lymphoma-associated antigen HD-CL-09, CTCL-associated antigen HD-CL-09, Dendritic cell-derived protein kinase, JNK/SAPK-inhibitory kinase, Jun kinase-inhibitory kinase, Kinase from chicken homolog A, hKFC-A, Thousand and one amino acid protein 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Also localized to the peripheral cell membrane.
Protein: CPFC_MYCA9
Sequence: MLFDAVLLLSFGGPEGPQEVRPFLENVTRGRGIPPERLDEVAEHYFHFGGVSPINGINRALVDQISRQLESAGHPLPVFFGNRNWHPMVEDTVAEMRDKGIRRAAVFTTSAWGGYSGCKQYVEDIARARAAVGDGAPELVKLRQYFDHPSLVQLYAEAVSAAMSSLRGEARLVFTAHSIPLAADRRHGPELYSRQVHYLAQLVAAATGHQDYDVVWQSRSGPPQVPWLEPDIVDHLAALKDRGIRSVAVAPIGFVSDHLEVVWDLDNEAREYAQEHDIELVRAATPGADERFARLAVDLITEVVEGRPALRASGVNPVPGYGFSVNGALCSPLCCGVQED
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STX3B_SCOAN
Sequence: EQLIRKDVXHXEXFAXXS
What are the official names of this protein?
Scolopendra 5920.47 Da toxin.
What is the protein family that this protein belongs to?
Belongs to the scolopendra toxin 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: YRA2_YEASB
Sequence: MDKAFDEIIGNSHTDSSSNHKVTRYRRRDLRNELGPRLGFAPSDAASRSKDRLYREREEPPLPKRIRISKIPLDVSDYTLDDMIKEFGSPIFSKIFDNKEDRTCIYEFEDPEVLEKIVERYNGHELHNAKIEVEIYQPQRKHSRMNAHNRRKQTAQEHGRGRPGSHYRQKPNRVSKKNKGREKNNTPTSVEALDAELDAYMKG
What is the function of this protein?
Involved in export of poly(A) mRNAs from the nucleus.  Recruited to the coding sequences as well as poly-A sites of active genes (By similarity).
What are the official names of this protein?
RNA annealing protein YRA2.
What is the protein family that this protein belongs to?
Belongs to the YRA1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURI_ALISL
Sequence: MPKNILIFDSGIGGLSVFKDIRYQIPLAKYIYAFDNAGFPYGELTEDILIERTSYIIQKLCHRHKIDIVVIACNTASTVVLPTLRTLLSIPVVGVVPAIKPAALVSQKIGLLATPATIKRSYTFDLIKSFASISDVKLLGSTRLVEMAEEKMVGIPVNLIELDEILKSWKGQVDCIVLGCTHFPFLRKEIKEILGRNVLLIDSGEAIARRVKQLLGSVDANKGDHLFGEVYCSASTKNEEALNKTFKELDFNPLQTLGYPKSLDR
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: NDHL_SYNY3
Sequence: MEDLLGLLLSETGLLAIIYLGLSLAYLLVFPALLYWYLQKRWYVASSVERLVMYFLVFLFFPGLLVLSPVLNLRPRRQAA
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit L, Inorganic carbon transport protein, NAD(P)H dehydrogenase I subunit L, NDH-1 subunit L, NDH-L.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhL subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: MATK_PINAT
Sequence: MDEFHRCGKEDSFWQQCFLYPLFFQEDLYAISHDHYLDVSSSSRPMEHLSSNDQLSFLTVKRLIGQIRQQNHSIVLFVNCDPNPLADRKKSFYSESVLEALTLVLEVPFSIWSKYSVEGMNESKSFRSIHSIFPFLEDKFPHSNSILDARIPYSIHPEILVRTFRRWIRDAPSLHPLRSVLYEYRNSPDNLQRSIIVVPRVNTRFFLFLWNYYVCECESILFSRLKRSSHSRSLSHGSFPQRTHFHRKIKHIIIFSRRNSLKSIWSLKDPKIHYVRYGERPIIAIKGAHLLVKKCRYYLLIFRQFYFHLWSEPYRVCSHQLSKNCSSSLGYFLRVRMNPILVRTKMLDELFIADLITDEIDPIVPIVPIIGLLATEKFCDISGRPISKLSWTSLTDDDILDRFDQIWRNLFHYYSGSFDRDGLYRIKYILSLSCAKTLACKHKSTIRVVRKELGPELFKKSFSKEREFYSLRFSSKAAARSQRERIWHSDIPQINPLANSWQKIQDLKIENLFDQ
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.