PharMolix/UniProtQA huggingface dataset:
Protein: CYSD_BRASO
Sequence: MTMDQVPISRSQLPAHLKRLESESIEIIREVAAELKNPVMLYSIGKDSGVMLHIAFKAFFPGRLPFPLLHVDTTWKFRDMIMFRDELAKKLGFDLLVHTNEDGLRAGINPFTSGPSLHTHVMKTEALKQALDLHGFDAAFGGARRDEEKSRAKERIFSFRAEGHVWEPRNQRPELWNLFNTRIRPGESLRVFPLSNWTEFDVWHYISLERIPVVPLYFAKERPVVWRDGTWIMVDDARFPLAPGETPQLRKVRFRTLGCYPLTGAIESAATSVEDILDEMRTTRISERQGRLIDTDEAASMEKKKKEGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: SRBS1_CAEEL
Sequence: MMHHPHPFGSNLANSSEPQQPSGQYLNPAADAYNFDTFEDSDKFSPKGNVAALRNVIHGQLDMKTPTGNSSRYQKPAPPPVDSTPSWAKNVKVYEPNGYVDPHLNKHNMGRVLDGPVNPNKYFQGVPPASYSQVKHNESKPPVPPSTKPPHSAAQALQAQVLQSSKAPSQPQQSQKTSYRIPYDVALDPRHHLGEFDIDDSASIISSCISTFGESSEIAGFSAAAEQRHLYEQYRKKLMEEKNELKEGSETPCVSLSEKVMTSSTENLKNGNNQQNQQPEPQPPSSSIFNSELTPFGHVAPVAKQFEPTNFPPFSPEKESEIKRSIDLESSQLLVKSKSPAPYSTSSTDHYGTIRRKHKPVAIDLSKSSPNLASQSPSNLFFGASFEEKQNRSPMTSTPSYKEQGFKNDSLNDSLNQAFEIASSIETTKNAYEAPPTPKSASHDRSISDTYPVSSSTTSTWPSHTTTPTTTTAAAPIAAVAPQTYTEQQPMSTSMSSSVMSTNMDEPIVVGSHQQIPQQSPDSSPERNEDMSQWYRKMFKQMHRKGEDGSNEGKEQHFINPSNVTDGIGRTTPTASNLGRSRENLSFNQHRPDHPSSYFDSLEHGPNDQYNNQERVKQSNEEELLRLKAEKLAEELRKEKERKHSFIPSSAPSLQNNMDRLNSLLYDFSSDIQEPAHRDYTPQPVMTATAVYKFEPRSARELPLNRGDIIRIIREVDGYWMEGERNGRSGIFPTSYVQINTGNQGDSQKMRAIYPFTARSDTELSLKRGEIITRRRQIDSNWLEGSNQIGIVGIFPASYVEPIEQVEQHIPTIVPNRPKTPKIEDQVYNQVYKPNETVIMQSNQGYYDKAAVVPNNKVRFDLPSGSDSNLQMSLNPHQNQFPPTHTQTSTQQPSNYGMKKIEYEREKVVEEVPPMHMDQYRKLNDEPKNPKKDTNILMNAASLIPKGSEMYRAVYPYQPQKEDELQLYTNDIIFVVEKCDDGWFIGTSLRTGDFGIFPGNYVKRH
What is the function of this protein?
Required for organization of sarcomeres in body wall muscles and for maintaining normal mitochondrial position in myocytes.
What are the official names of this protein?
Sorbin and SH3 domain-containing protein 1 homolog.
What are the subcellular locations of this protein?
Cell junction, adherens junction. Cell membrane. Cell junction, focal adhesion. Note=Localizes to adhesion plaques and dense bodies between myocytes (PubMed:28978740). Co-localizes with deb- 1 and atn-1 at dense bodies (PubMed:28978740). Predominantly localizes to the membrane-proximal region of dense bodies (PubMed:28978740).
Protein: Y305_SYNY3
Sequence: MADYLLNALQWIDGLGTWAAIAFMLLYTVATVVFLPGSILTLGAGVVFGVILGSIYVFIGATLGATAAFLVGRYLARGWVAKKIAGNQKFKAIDEAVGKEGLKIVILTRLSPVFPFNLLNYAYGITNVSLKDYVIGSLGMIPGTIMYVYIGSLAGSLATLGTATNQANPTLQWTIRIVGFIATVAVTIYVTKIARKALNEAILTSEVDE
What are the official names of this protein?
TVP38/TMEM64 family membrane protein slr0305.
What is the protein family that this protein belongs to?
Belongs to the TVP38/TMEM64 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YQIG_ECOLI
Sequence: MSGNIGANPVIIIGCASAYAVEFNKDLIEAEDRENVNLSQFETDGQLPVGKYSLSTLINNKRTPIHLDLQWVLIDNQTAVCVTPEQLTLLGFTDEFIEKTQQNLIDGCYPIEKEKQITTYLDKGKMQLSISAPQAWLKYKDANWTPPELWNHGIAGAFLDYNLYASHYAPHQGDNSQNISSYGQAGVNLGAWRLRTDYQYDQSFNNGKSQATNLDFPRIYLFRPIPAMNAKLTIGQYDTESSIFDSFHFSGISLKSDENMLPPDLRGYAPQITGVAQTNAKVTVSQNNRIIYQENVPPGPFAITNLFNTLQGQLDVKVEEEDGRVTQWQVASNSIPYLTRKGQIRYTTAMGKPTSVGGDSLQQPFFWTGEFSWGWLNNVSLYGGSVLTNRDYQSLAAGVGFNLNSLGSLSFDVTRSDAQLHNQDKETGYSYRANYSKRFESTGSQLTFAGYRFSDKNFVTMNEYINDTNHYTNYQNEKESYIVTFNQYLESLRLNTYVSLARNTYWDASSNVNYSLSLSRDFDIGPLKNVSTSLTFSRINWEEDNQDQLYLNISIPWGTSRTLSYGMQRNQDNEISHTASWYDSSDRNNSWSVSASGDNDEFKDMKASLRASYQHNTENGRLYLSGTSQRDSYYSLNASWNGSFTATRHGAAFHDYSGSADSRFMIDADGTEDIPLNNKRAVTNRYGIGVIPSVSSYITTSLSVDTRNLPENVDIENSVITTTLTEGAIGYAKLDTRKGYQIIGVIRLADGSHPPLGISVKDETSHKELGLVADGGFVYLNGIQDDNKLALRWGDKSCFIQPPNSSNLTTGTAILPCISQN
What is the function of this protein?
May be involved in H(2) production during fermentative growth (PubMed:24025676).  Involved in the export and assembly of a fimbrial subunit across the outer membrane (Probable).
What are the official names of this protein?
Putative outer membrane usher protein YqiG.
What is the protein family that this protein belongs to?
Belongs to the fimbrial export usher family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: CM1_MAIZE
Sequence: MAFKLATKAAAASPAAAHRGGLARGPEGTSRVAFGPAPRNKGLRAANNSATPVAKEERVDRSEILTLDSIRQVLIRLEDSIIFGLLERAQFCYNADTYDSNAFHMDGFGGSLVEYMVRETEKLHAQVGRYKSPDEHPFFPEDLPEPRLPPMQYPRVLHPIADSININKEIWKMYFDELLPRLVKKGSDGNAGSSALCDTTCLQALSKRIHYGKFVAEAKFQESPEAYMPAIIAQDRDQLMHLLTYETVERAIEHRVEAKAKIFGQEVNIGVEDNGSPPVYKIVPSLVAELYSYRIMPLTKEVQIAYLLRRLD
What is the function of this protein?
May play a role in chloroplast biogenesis.
What are the official names of this protein?
Chorismate mutase 1, chloroplastic, ZmCM1.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SUCC_PELPD
Sequence: MKIHEYQAKDILAGFGIAIPRGRVAMNASQVERAARELGGHCVIKAQVYAGGRGKGGGIRVAQDPGQAGEIAKELLGTKLVTPQTGPEGLEVRRLLVEEVVDIERELYLSITLDRESSRYCLIASAEGGMDIEEIARTAPDRIRILTIDPFIGLRSYQARRTALGLGLVGPLCEECVELILNLYRCLLERDCSLVEINPLVVTNAGWLVAMDTKMTFDDNALQRHCEYPDLVDYSQLNPLEIAAARFDLSYIKLSGAIGCMVNGAGLAMATLDVLKEAGGEPANFLDVGGGASREKVAEAFRIILQDRDVRGVFVNIFGGIMRCDIIAQGIIDAASGGGCRLPIVVRMDGNRVEEGKQLLRESGLNIRIGENMGDGAQQIVAMLNREVNQPCQS
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: DHX8_DROME
Sequence: MDELQKLEYLSLVSKICTELDNHLGINDKDLAEFIIDLENKNRTYDTFRKALLDNGAEFPDSLVQNLQRIINLMRPSRPGGASQEKTVGDKKEDKKSQLLKMFPGLALPNDTYSKKEESDDDEKVKAKPEKHSETHKKTDMSDVDAAMMELEALAPGEGATLVRPHKEVSSRDRHKRRSRDRDTKRRSRSREDRHSDRRRSRSRDKERRRRSRSRDNRRRSRSREDRDRDRDRRHKSSSSRDHHERRRRSRSRSTERRDRRDRSRDCSEKMPPPSAAMTDDPEAGKIYSGKIANIVPFGCFVQLFGLRKRWEGLVHISQLRAEGRVTDVTEVVTRNQTVKVKVMSITGQKVSLSMKEVDQDSGKDLNPLSHAPEDDESLRDRNPDGPFSSSTSMLNLQGNGMEGDEHESRKRVTRISSPERWEIKQMISSGVLDRSEMPDFDEETGLLPKDEDDEADIEIEIVEEEPPFLSGHGRALHDLSPVRIVKNPDGSLAQAAMMQSALSKERREQKMLQREQEIEAMPTSLNKNWIDPLPEDESRSLAANMRGMAAAPPEVPEWKKHVIGGKKSSFGKKTDLTLVEQRQSLPIYKLRDDLIKAVTDNQILIVIGETGSGKTTQITQYLGECGFTARGKIGCTQPRRVAAMSVAKRVAEEYGCRLGQEVGYTIRFEDCTSPETIIKYMTDGMLLRECLMEAELKSYSVIMLDEAHERTIHTDVLFGLLKTAVQKRPELKLIVTSATLDAVKFSQYFFKAPIFTIPGRTFPVEVLYTKEPETDYLDASLITVMQIHLREPPGDILLFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPAGSRKVVIATNIAETSLTIDGIFYVVDPGFVKQKVYNSKTGMDSLVVTPISQAAAKQRAGRAGRTGPGKTYRLYTERAYRDEMLPTPVPEIQRTNLATTVLQLKTMGINDLLHFDFMDAPPVESLVMALEQLHSLSALDDEGLLTRLGRRMAEFPLEPNLSKMLIMSVALQCSDEILTIVSMLSVQNVFYRPKDKQALADQKKAKFNQAEGDHLTLLAVYNSWKNNKFSNAWCYENFVQIRTLKRSQDVRKQLLGIMDRHKLDVVSAGKNSVRIQKAICSGFFRNAAKKDPQEGYRTLVDSQVVYIHPSSALFNRQPEWVIYHELVQTTKEYMREVTTIDPKWLVEFAPSFFRFSDPTKLSKFKKNQRLEPLYNKYEEPNAWRISRVRRRRN
What is the function of this protein?
Involved in pre-mRNA splicing as component of the spliceosome (PubMed:18981222, PubMed:24244416).  Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome (By similarity).  Before and after egg-chamber formation, required for nurse-cell chromatin dispersal (NCCD) probably by playing a role in spliceosome localization to chromatin/interchromatin spaces (PubMed:24244416).
What are the official names of this protein?
ATP-dependent RNA helicase DHX8, Peanuts.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. DDX8/PRP22 sub-subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CL4A1_GLORO
Sequence: MAKNAMLCLLILRVVLALAFATNKKGDEEPENHSTGIFGKVGRVVTVALAMSSRLGGADATRGGGAVYGRDLKSNQLPNNNWMAPPPPMAIRSAKVYDSKHSPAEYLKKFAQDFRRKTGMHSQRHHEETTLEQEKRVAGAGPDPIHHQDTTLEQEKRAVPAGPDPKHHEETTLEQEKRAVPAGPDPKHHEETTLEQEKRAVPAGPDPKHHEETTLEQEKRAVPAGPDPKHHEETTFEQEKRGAPAGPDPIHH
What is the function of this protein?
Mimics host plant CLE extracellular signal peptides that regulate cell fate.  May play a role in the differentiation or division of feeding cells (syncytia) induced in plant roots during infection.
What are the official names of this protein?
CLAVATA3/ESR (CLE)-related protein 4A-1.
What is the protein family that this protein belongs to?
Belongs to the CLV3/ESR signal peptide family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host extracellular space. Secreted, extracellular space, apoplast. Note=Present in secretory granules within the dorsal esophageal gland secretory cell and in the dorsal gland ampulla (collecting reservoir) at the base of the nematode stylet. Secreted into host root cells via the nematode stylet to transform the recipient cells into enlarged multinucleate feeding cells called giant-cells or syncytia. Secreted to the host apoplasm from its cytoplasm via a plant secretory pathway (By similarity).
Protein: HEM1_CALBD
Sequence: MLWVIGINHKVEVDIRQKFSLIKTKLQEKLISLKKLANEVIILSTCNRTEIYFFSEEYVDIEKIFTELDWDKRYMHLFYIYKDKDCIKHLFEVVCGFDSLLIGEDQIVAQVKEAKEISKLVGGKNPVLERLFEVALKCSKEFRTKARLNEHPITIASVVGKVLKESNIRKIAIIGLGNIGILFCNYFKNSDVDKVFLIGRKNEKIDQFVKLNPEKFRYYDKKKTILEAQCLICSTSAPHSVVHKDDIPEGKNLLIFDLAVPRDVDVEVYELPNVKVIDIDQVHKIDTINREFRISKMQENYHIIDKYVDEFIDWLEFRQYRNLIMEMKRHAEQLCKAQVKYIKNVDSRERKEVERLLIRMANLYIDRAIEVLREAHKEGSGEICSNLIKRIFLK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: MOT10_MOUSE
Sequence: MVPSQEEPAAERETNEAQPPGPAPSDDAPLPGPGPSDVSDVAAEKVEVELTRSAGSEPPVPPEGGWGWLVMLAAMWCNGSVFGIQNAYGVLFVSMLDTFKAKDDDNMAFKTAWVGSLSMGMIFFCCPIVSVFTDMFGCRRTAVVGAAVGFIGLMSSSFVSSIEPLYLTYGIIFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLGNLISSVKLFNTLRILCIFMFVLFLAGFTYRPLVPSTKEKESGGSRSSFFSRRKLSPPKKVFNFALFKETTYAVWAAGIPLALFGYFVPYVHLMNHVKERFQDVNNKEVLFMCIGITSGVGRLLFGRIADYLPGVKKVYLQVLSFFFIGLMSMMIPLCSAFGALIAVCLAMGLFDGCFISIMAPIAFELVGPQDASQAIGFLLGFMSIPMTVGPPIAGLLHDKLGTYDVAFYLAGIPPFVGGVVLCLIPWIHSKKQRKISKNAGGEKMEKMLENQSSLLSGSSGIFKKDSASII
What is the function of this protein?
Sodium- and proton-independent thyroid hormones and aromatic acids transporter.  Mediates both uptake and efflux of 3,5,3'-triiodothyronine (T3) and 3,5,3',5'-tetraiodothyronine (T4) with high affinity, suggesting a role in the homeostasis of thyroid hormone levels (By similarity).  Responsible for low affinity bidirectional transport of the aromatic amino acids, such as phenylalanine, tyrosine, tryptophan and L-3,4-dihydroxyphenylalanine (L-dopa) (PubMed:16245314).  Plays an important role in homeostasis of aromatic amino acids (PubMed:23045339).
What are the official names of this protein?
Monocarboxylate transporter 10, MCT 10, Aromatic amino acid transporter 1, Solute carrier family 16 member 10, T-type amino acid transporter 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane. Note=Detected in basolateral membrane of kidney proximal tubule starting at he beginning of the proximal tubule epithelium within the glomerular capsule and extending to the S1 and S2 segments. Localizes also to the basolateral membrane of small intestine enterocytes and to sinusoidal side of perivenous hepatocytes.
Protein: BRPF1_HUMAN
Sequence: MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRKHKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVSEDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVVYRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSSEKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLLENQKHLPVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGPERHGPSSRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSSDSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASDRTSTTPSKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGWLSEDEDSPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGEQSSETSDSD
What is the function of this protein?
Scaffold subunit of various histone acetyltransferase (HAT) complexes, such as the MOZ/MORF and HBO1 complexes, which have a histone H3 acetyltransferase activity (PubMed:16387653, PubMed:24065767, PubMed:27939640).  Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H3 'Lys-14' acetylation (H3K14ac) (PubMed:24065767).  Some HAT complexes preferentially mediate histone H3 'Lys-23' (H3K23ac) acetylation (PubMed:27939640).  Positively regulates the transcription of RUNX1 and RUNX2 (PubMed:18794358).
What are the official names of this protein?
Peregrin, Bromodomain and PHD finger-containing protein 1, Protein Br140.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Cytoplasm. Note=Localization to the nucleus depends on KAT6A, ING5 and MEAF6 (PubMed:18794358, PubMed:27939640). Localizes to transcription start sites (PubMed:24065767).
Protein: RK14_MAIZE
Sequence: MIQPQTLLNVADNSGARKLMCIRVIGAAGNQRYARIGDVIIAVIKDAVPQMPLERSEVIRAVIVRTRKEFKGDDGIIIRYDDNAAVIIDQKGNPKGTRVFGAVAEELRELNLTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y2812_YERP3
Sequence: MNRKKIIVAAVIVALLATLAYGWHYYRQQNDASLTLYGNVDIRTVNLGFRVAGRLASLAVDEGDDIHPGQTLGKLDDGPYLNALKQAQANVQSAQAQLALLKAGYREEEIAQVRSEVAQRQAAFDYADNFLKRQQGLWASKAVSANELENARTARNQAQANLQAAKDKLAQFLSGNRPQEIAQAEANLAQTEAELAQAQLNLQDTILLAPSAGTVLTRAVEPGTILSASNTVFTVSLTDPVWVRAYVSERHLGQAIPGSEVEVFTDGRPDKPYHGKIGFVSPTAEFTPKTVETPDLRTDLVYRLRIIITDADESLRQGMPVTVRFPQR
What are the official names of this protein?
UPF0194 membrane protein YpsIP31758_2812.
What is the protein family that this protein belongs to?
Belongs to the UPF0194 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CCA_LACLA
Sequence: MKLEKLPEEFVQAKPVLEKIIEHGFEAYFVGGSVRDILLGREIHDVDIATSAYPEEIKDIFPYTIDVGIEHGTVLVLAGKSEAEHYEITTFRTESKYTDYRRPDHVDFVRDLREDLKRRDFTINAFACDVNGQIIDLFDGLTDLKERRLTAVGSALERFNEDALRIMRAMRFAATLDFQIENKTFLAMCESAHLLEKISVERIFIEFDKLLLGQDWRNGLTLLLKSGAYKYLPDLQDSALKKVLTDLSVDFHFQNSEQAWAALLTRFSNVDVKTFLRKWKVSNEFAKFVADLVSAYELDSWDLMSLYHFGLEKVLLVDELKVAYGLKINREQAVTINNQLQIHDKSEIVIAGKDLMEEFSLEPGPELGKILKIIEEKIVKNELKNEQAAIFAEVKKML
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
Protein: METK_DECAR
Sequence: MSDYLFTSESVGEGHPDKVADQISDAILDAILAQDKHSRVAAETLCNTGLVVLAGEITTNANVDYIQVARDTIKRIGYDNTEYGIDYKGCAVLVAYDKQSPDIAQGVNAAYDDNLGQGAGDQGLMFGYACDETPSLMPLPIYLSHRMVERQAMLRKDGRLPWARPDAKSQVTIRYVDGKPHSIDTVVLSTQHSPDISLEDLREATIEQIIKPVLPKELIKGDIKYLVNPTGRFVVGGPQGDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYATRYVAKNIVAAGLASRCLVQVSYAIGVAEPTSIMVETYGTGKVSNETLTALVRKHFDLRPKGIVNMLDLLRPIYQKTAAYGHFGRDEPEFTWEATDRANLLKSDAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO11_THEON
Sequence: MRIEVIKREENVLEFYLEGEDHTFANLLNEVLHENEHVTFAGYTIEHPVLMARKPKFRVVTDGKITPEQVLEEAAQKIFDRARAVLEAWKEVLGE
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit L.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPX1_HELAN
Sequence: MATQSKKTLYDFTVKDAKGNDVDLSVYKGKVVLIVNVASKCGLTNNSYDELNQIYLKYKEKGFEILAFPCNQFGQQEPGTNEEIVDFVCTKFKSEFPIFDKIDVNGENAAPVYEFLKTGFYGILGGDIQWNFSKFLVDKNGQPVDCYYPTTSPLTVERDIQKLLGLL
What is the function of this protein?
May constitute a glutathione peroxidase-like protective system against oxidative stresses.
What are the official names of this protein?
Glutathione peroxidase 1.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
Protein: IHFB_SHESR
Sequence: MTKSELIEKLATRQSQLSAKEVEGAIKEMLEQMATTLESGDRIEIRGFGSFSLHYRAPRTGRNPKTGSSVELEGKYVPHFKPGKELRERVDAVNV
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: ACPS_STRP8
Sequence: MIVGHGIDLQEISAIEKVYQRNPRFAQKILTEQELAIFESFPYKRRLSYLAGRWSGKEAFAKAIGTGIGRLTFQDIEILNDVRGCPILTKSPFKGNSFISISHSGNYVQASVILEDKK
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_SALTY
Sequence: MALLDFFLSRKKSTANIAKERLQIIVAERRRSDAEPHYLPQLRKDILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEESK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: E4PD_ECOL5
Sequence: MTVRVAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGMAHLLKYDTSHGRFAWEVRQERDQLFVGDDAIRVLHERSLQSLPWRELGVDVVLDCTGVYGSREHGEAHIAAGAKKVLFSHPGSNDLDATVVYGVNQDQLRAEHRIVSNASCTTNCIIPVIKLLDDAYGIESGTVTTIHSAMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLAAGITRFFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKANEVNLLLQKAAQGAFHGIVDYTELPLVSVDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMATVAFR
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLND_AZOBR
Sequence: MLSTRAASADASDAKDAGTANIPNKRAILSRRKLAEDLETLVAEHGTGDKLRPALIARLRGALNDGRAEVRARFEAKGSGEDCVRQNCYLADGVVRSLADLTVTHIFPTPNPTSGEVFDIVATGGYGRGELAPFSDIDLLFLLPYKRTPRVEQVVEYMLYILWDLGLKVGHAVRSVDDCIRQSKADVTIRTAILESRYLWGPRKLFHRLRRRFDREVVAGTGPEFVEAKLAERDNRHLKLGDSAYVLEPNLKDGKGGLRDLQTLFWIAKYLYRVEDVDDLVGKKVLLPEEAHGFAKAQNFLWTARCHLHYLTGRMEDRMTFDVQTSIGNRMGYTDHAGTKGVERFMKHYFLVAKDVGDLTRIFCAALEAESKRPPKFNILRLAALARRKDVDGFVVDGERLNVRSDRQFKDEPLDMIRLFHTAQQNDIDIHPNALRAITRSLSVVGPKLRADPEANRLFLEILTGRKDPEITLRRMNEAGVLARFIPDFGRVVAQMQYDMYHVYTVDEHTLFALGILHKIEMGELTDELPLSSEVIHKVVSRRALYVAVLLHDIAKGRGGDHSILGARVAEKLCPRLGLTAEETETVAWLVRWHLAMSYTAFKRDLEDDKTVRDFVSLVQSPERLRLLLVLTVADIRAVGPQRWNNWKATLLRELYNRSEEVMSGGLSVEGRGRRIQAAQAALRDELSDFDAADFERHLALGYPAYWLAFDAETLGRQARLVRGRLRDERPLTVNTRIDRGRAITEVTIFATDHHGLFSRLAGALAAAGADIVDARIFTMTNGMALDVFTVQDAAGGGAFESGDKLAKLSVMIEKVLSGQLKPLHDLTKRKAPHASRTRVFHVPPRVLIDNNASTTHTVIEVNGRDRPGLLYDLTRALTNLTLQISSAKISTYGEKAIDVFYVKDVFGLKVTHENKLAQIRERLLHALADPSA
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins GlnB and GlnZ, in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: DNAA_YERPE
Sequence: MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPNRFVLDWVRDKYLNNINGLLNDFCGTEVPLLRFEVGSKPAARAHNNPVTASVSAPVAPVTRSAPMRPSWDNSPAQPELSYRSNVNPKHTFDNFVEGKSNQLARAAARQVADNPGGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKANAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFIAKRLRSNVRELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVADLLSKRRSRSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREESHDIKEDFSNLIRTLSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGT8_YEAST
Sequence: MKSQKIHNQKDREKVEIYFYLKILINISTIHVITDYYFYLCQRWLARGCCEVTSKRF
What are the official names of this protein?
Putative uncharacterized protein YGL188C.