PharMolix/UniProtQA huggingface dataset:
Protein: RLME_LEGPH
Sequence: MNRTKSSKRWLQEHFDDVYVKKAQAEGYRSRAVYKLKEIDDKESLIKPGMTVVDLGAAPGGWTQYASEKMRGSGRLVALDILPMDALPNVEFILGDFREDNVLQELINLIPQRTLDLLLSDMAPNMSGSSAIDIPRAMYLVELAFDFAEKMLKPGGNMLVKIFHGSGFDELVKQARASFEKVVIRKPSASRSRSKETYLLAKGYNL
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR7_TYPAN
Sequence: MSRRGTAEEKTAKSDPIYRNRLVNMLVNRIMKHGKKSLAYQIIYRAVKKIQQKTETNPLSVLRQAIRGVTPDIAVKARRVGGSTHQVPIEIGSTQGKALAIRWLLGASRKRPGRNMAFKLSSELVDAAKGSGDAIRKKEETHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RR4_HAPHO
Sequence: MSRYRGPRMKIIRRLGSLPGLTNKVLRSKPGYTDQLISNKKVSQYRIRLEEKQKLRFHYGLTERQLLKYVRIARKAKGSTGNVLLQLLEMRLDNVIFRLGMSSTIPGARQLVNHRHIMINDEMVDTPGYNCKPRDIITLKNISESRSGIPKGIDSSQRSRTPNHLVFDSSRGVGFVNQIIDREWISLKINELLVVEYYSRQA
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CH60_METPB
Sequence: MAAKDVRFSADARDKMLRGVDILADAVKVTLGPKGRNVVIEKSFGAPRITKDGVTVAKEIELADKFENMGAQMVREVASKTNDIAGDGTTTATVLAQAIVREGAKFVAAGINPMDLKRGIDLATQAAVKDITARAKKVASSEEVAQVGTISANGDKEIGEMIAHAMQKVGNEGVITVEEAKTAETELDVVEGMQFDRGYLSPYFVTNAEKMVAELEDPYILIHEKKLSSLQPMLPVLEAVVQTGKPLLIIAEDIEGEALATLVVNKLRGGLKVAAVKAPGFGDRRKAMLEDIAILTKGQTISEDLGIKLENVALPMLGRAKRVRIEKENTTIIDGLGEKADIEARVGQIKAQIEETTSDYDREKLQERLAKLAGGVAVIRVGGATEVEVKEKKDRVDDALNATRAAVEEGIVPGGGTALLRAKKAVAELKSDVPDVQAGIKIVLKALEAPIRQIAQNAGVEGSIVVGKITDNTGSETYGFNAQTEEYVDMIQSGIVDPAKVVRTALQDAASVAGLLVTTEAMVADAPKKDSPAPAMPGGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEN1_ARATH
Sequence: MAGGGKHTPTPKAIIHQKFGAKASYTVEEVHDSSQSGCLGLAIPQKGPCLYRCHLQLPEFSVVSNVFKKKKDSEQSAAELALDKLGIRPQNDDLTVDEARDEIVGRIKYIFSDEFLSAEHPLGAHLRAALRRDGERCGSVPVSVIATVDAKINSRCKIINPSVESDPFLAISYVMKAAAKLADYIVASPHGLRRKNAYPSEIVEALATHVSDSLHSREVAAVYIPCIDEEVVELDTLYISSNRHYLDSIAERLGLKDGNQVMISRMFGKASCGSECRLYSEIPKKYLDNSSDASGTSNEDSSHIVKSRNARASYICGQDIHGDAILASVGYRWKSDDLDYDDVTVNSFYRICCGMSPNGIYKISRQAVIAAQLPFAFTTKSNWRGPLPREILGLFCHQHRLAEPILSSSTAPVKSLSDIFRSHKKLKVSGVDDANENLSRQKEDTPGLGHGFRCEVKIFTKSQDLVLECSPRKFYEKENDAIQNASLKALLWFSKFFADLDVDGEQSCDTDDDQDTKSSSPNVFAAPPILQKEHSSESKNTNVLSAEKRVQSITNGSVVSICYSLSLAVDPEYSSDGESPREDNESNEEMESEYSANCESSVELIESNEEIEFEVGTGSMNPHIESEVTQMTVGEYASFRMTPPDAAEALILAVGSDTVRIRSLLSERPCLNYNILLLGVKGPSEERMEAAFFKPPLSKQRVEYALKHIRESSASTLVDFGCGSGSLLDSLLDYPTSLQTIIGVDISPKGLARAAKMLHVKLNKEACNVKSATLYDGSILEFDSRLHDVDIGTCLEVIEHMEEDQACEFGEKVLSLFHPKLLIVSTPNYEFNTILQRSTPETQEENNSEPQLPKFRNHDHKFEWTREQFNQWASKLGKRHNYSVEFSGVGGSGEVEPGFASQIAIFRREASSVENVAESSMQPYKVIWEWKKEDVEKKKTDL
What is the function of this protein?
Methyltransferase that adds a methyl group to the ribose of the last nucleotide of small RNAs (sRNAs).  This protects the 3'-end of sRNAs from uridylation activity and subsequent degradation.  Can methylate 3'-end of microRNAs (miRNAs), small interfering RNAs (siRNas) and trans-acting small interfering RNAs (ta-siRNAs).  Involved in plant development through its role in small RNAs processing.  Required for the specification of reproductive organ identities and the probable repression of A class genes.  May control floral determinacy possibly by regulating the expression of the C class floral homeotic gene AGAMOUS (AG).
What are the official names of this protein?
Small RNA 2'-O-methyltransferase, Protein CORYMBOSA 2, Protein HUA ENHANCER 1, S-adenosylmethionine-dependent RNA methyltransferase HEN1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. HEN1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BNL2B_EBVB9
Sequence: MRPGRPLAGFYATLRRSFRRMSKRSKNKAKKERVPVEDRPPTPMPTSQRLIRRNALGGGVRPDAEDCIQRFHPLEPALGVSTKNFDLLSLRCELGWCG
What are the official names of this protein?
Uncharacterized protein BNLF2b.
What is the protein family that this protein belongs to?
Belongs to the lymphocryptovirus BNLF2b family.
Protein: MURF_STRTO
Sequence: MIPLGLGEIAEIVGGKATGESVTVTAPAVLDSRQAEPGGLFVAFAGEHADGHDYAERAGRAGAVAVLGSRPTSLPTVVVEDVRTALQTLAAHVVARLRDGLTVVGVTGSQGKTGTKDLLAAVLSGAGPTVATTGSLNNELGVPLTMLRAQAATRFLVLEMGARHEGDIAELTGLVAPDIAVVLNVGVAHLGEFGSRAAIARAKGELVQGLVPGGTAVLNADDPRVASMSVLTDGPVLTFGRTDPADVQVLDVVLDRLGRPSCTLRTVDTSARLALPLVGAHQALNASAAAAAALAAGVPLDLATTALTTASLSPWRMELRDLACGATLLNDSYNANPDSTRAALDALSAIEGGRRIAVLGEMLELGDGSEAEHRAVGAYAAARADVVVAVGEAARPLADGAGERAVVLAGNDAAVDWLRDHLAAGDVVLVKASRGARLDEVAAGLA
What is the function of this protein?
Involved in cell wall formation.  Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
What are the official names of this protein?
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase, D-alanyl-D-alanine-adding enzyme, UDP-MurNAc-pentapeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_METM5
Sequence: MVLTNSKQPRKQRKALYNAPLHLRNSVMAAMLSKELKEKFNKNSLPVKKGDTVKVLRGNFKGIEGEVSKVDYAGYKIIVEGVVNKKQDGTETAYPIHPSNVMITKLDESDEKRFKNSSN
What is the function of this protein?
Located at the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: CCNC_XENLA
Sequence: MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLISAATSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDARQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMASILSKMPKPKPPPNSDGEQGTNGSQSSGYSQS
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.  Binds to and activates cyclin-dependent kinase cdk8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex (By similarity).
What are the official names of this protein?
Cyclin-C.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin C subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y738_OCEIH
Sequence: MLENAFIMLAIIFSVNVIYVSLMTVRMILTLKGRTYIAAFVSMFEIVIYVVGLGLVLDNLDQIQNLVAYAIGFGTGLVIGAKIEEKLALGYITVNVVSANPDLKFTQRLREKGYGVTSWSSYGREGDRLSVQILTPRKYELRLYETIQEIDPKAFIISYEPKRIHGGFWVKQVRKGKLMNPKKKKNTNTVESENEQK
What are the official names of this protein?
UPF0316 protein OB0738.
What is the protein family that this protein belongs to?
Belongs to the UPF0316 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BRNQ_HAEIN
Sequence: MFSRKDIIVLGMMIFALFLGAGNIIFPPMEGFSSGQHWTSASLGFVLTGVLMPFITLVVVAILGRGEELTKDLPKWAGTGFLVILYLTIGSTFAMPRITNVAYEMAWLPLGLTENNANVRFVFSLIFNLIAMGFMISPNTIISSVGKFMTPALLVLLIAVAITVFISPLSEIQAPSNAYENSHSLLIGLTSGYQTMDVLAAIAFGGIVARALSAKNVTKTKDIVKYTISAGFVSVILLAGLYFSLFYLGATSAAVAEGATNGGQIFSRYVNVLFGSAGTWIMAGIIVLASLTTLVGVTSASADYFSKFSVRFSYPFWAALFTAMTITVSQYGLTDLLRITIPALLLIYPVAIVLVLLQFLRKKLPSIKFTYNSTLLVTVCFSLCDSLNNVKMLPESINSLLKHFPLSSEGMAWLVPTLVMLVASIFIGKALHKTHS
What is the function of this protein?
Branched chain amino acid transport system, which transports leucine, valine and isoleucine.
What are the official names of this protein?
Branched-chain amino acid permease BrnQ, BCAA permease, Branched-chain amino acid transport system carrier protein, Branched-chain amino acid uptake carrier.
What is the protein family that this protein belongs to?
Belongs to the branched chain amino acid transporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MALNB_MALOL
Sequence: DETXTDEEFN
What is the function of this protein?
Significantly inhibits growth and induces an apoptotic response in HeLa cells through cell-cycle arrest at S-phase.  Exhibits highly cytotoxic activities against cancer cell and non-cancer cell lines producing IC(50) values of 0. 15 nM for human cervical carcinoma cells (HeLa), 7. 71 nM for rat pheochromocytoma-12 cells (PC-12), 11. 20 nM for human breast cancer cells (MCF-7), 15. 80 nM for human leukemia cells (K562), 2. 79 nM for African green monkey kidney cells (Vero) and 3. 92 nM for normal Madin-Darby canine kidney cells (MDCK).
What are the official names of this protein?
Malanin chain B.
Protein: SECA_STRM5
Sequence: MINSLLTRVFGSRNERQLRQLNRIVAKINALEPEIEKLSDEQLQAKTPEFKQRIADGEALDKVLPEAFAVCREAGRRVLGMRHYDVQLIGGMVLHLGKIAEMRTGEGKTLVATLPVYLNALEGKGVHVVTVNDYLARRDAAQMGKLYNWLGLSVGVVYPGMPHSDKREAYASDITYGTNNEFGFDYLRDNMALSKADRYQRGLHYAIVDEVDSILIDEARTPLIISGPADDSPELYIRVNRVVPNLVKQEAEDGEGDFWVDEKGKQVHLSEAGMEHAEQLLVEAGILDGETEGLYAPQNLTVVHHLNAALRAHAIYQRDVDYIVRDGEVVIVDEFTGRTLSGRRWSDGLHQAVEAKEGVPVQRENQTLASITFQNLFRMYKKLSGMTGTADTEAFEFQSIYGLEVVVIPTNRPTIRKDSPDQVFLNRKGKFNAVLADIEECAKRGQPVLVGTTSIETSEMLSEHLAKAGVKHEVLNAKQHDREATIVANAGRPAAVTIATNMAGRGTDIVLGGSLEAEIHELGEDATDAQKAAVKAEWQQRHDAVKAAGGLHIVGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLEDNLMRIFASDWVQKAMRMMGMKEDDVIEDRLVSRQIEKAQRKVEAHNFDIRKNLLDFDDVNNDQRKVIYAQRDELLDAESVKDNVDGIRDDVIFDIVARFVPPNSIDEQWDLRGLEATLESDFGLQMSLTGLVKEHEELDAEAIAAKVQERVNQHFAEKEAGVGEETMRALEKHVMLTVLDQSWKEHLARMDYLRQGIYLRGYAQKQPKQEYKKEAFELFSDMLENVKREVVTLLSRVRIRSDEEVQALEAAERQQVEARLSQSQFQHQDVGSYSADEEAAQVQAAQQGIAQVQRDEPKIGRNDPCPCGSGKKYKHCHGQLS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: RL17_GEOSW
Sequence: MSYRKLGRTSAQRKALLRDLATDLIINERIETTEARAKELRSVVEKMITLGKRGDLHARRQAAAFIRKEVANSETGQDALQKLFSDIAPRYQDRQGGYTRIMKLGPRRGDGAPMVIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: TOLB_VIBVU
Sequence: MKKRLLMGLLVLLSSVTNVANAALELIITDGIDSARPIAIVPFKWQGTKALPVDISSVVASDLQRSGKFSPVPTSKMPQTPYNESEINFDAWTNLGVDTLLTGSVTQNEKGEYVINYQLVDVVRGQLTSGQSRALEDGQLVLSKDHVLFNKVATITAPRMREYAHRISDLIYEQLTGERGAFLTRIAYVVVNDKDKFPYQLRVADYDGFNERLVLRSKQPLMSPAWSPDGRRLAYVSFQNGQAEIFVLNIYTGEHEKLTSFPRHNGAPRFSPDGKKLAIVLSKTGSLQIYTLDLQTRQLTQITRDRSNNTEPFWHPDGKSLIFTSDRGGKPQIYRVNLSDGSTSRLTWQGSQNLGGQITPDGRFLIMVNRSDSGFNLAKQDLETGAVQVLTKTLLDESPSIAPNGGMVIYSSIYDKKNVLSMVSIDGRFKARLPATNGRVRAPAWSPFL
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: KDPC_STAAT
Sequence: MNTIRNSICLTIITMVLCGFLFPLAITLIGQIFFYQQANGSLITYDNRIVGSKLIGQHWTETRYFHGRPSAVDYNMNPEKLYKNGVSSGGSNESNGNTELIARMKHHVKFGNSNVTIDAATSSGSGLDPHITVENALKQAPRIADARHVSTSRVADLIQHRKQRGVLTNDYVNVLELNIALDKMKD
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ALMA1_DURXX
Sequence: MPLILGGLAGAAAGYGAAAWLERRKPPPGKDPNIKHASLGVVRLDWHYHPLPGDVGSPDSFEYPVYYRAVPGLTFEICQSGKMSPEIQQNFKDAIEFLDKERGVSVITSDCGFFMWFQKEARLYTSKPVVMSSLALLPSLHAAIGTDGKIAIFSANSTSLGPMHDTVAKECGVDWDEACYVLVGCQDVEGFEAVASGEPLDLEKVTPGIVRKAKQVIAEHPDIHAILMECTQLPPFSDDVRAATGLPVYDAIVSADFFIRGFVDNPRFGLNDWHRPWDGHQEKYKLGDNVQDKEKLLHYKP
What is the function of this protein?
Mediates cleavage of dimethylsulfonioproprionate (DMSP) into dimethyl sulfide (DMS) and acrylate.  DMS is the principal form by which sulfur is transported from oceans to the atmosphere and is a key component of the ocean sulfur cycle.
What are the official names of this protein?
Dimethylsulfonioproprionate lyase, DMSP lyase, Symbiodinium-A1.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family. ALMA1 subfamily.
Protein: CNGA2_RABIT
Sequence: MTEKSNGVKSSPANNHNNHVPATIKANGKDESRTRSRPQSAADDDTSSELQRLAEMDAPQQRRGGFRRIVRLVGVIRQWANRNFREEEARPDSFLERFRGPELQTVTTQQGDGKGDKDGDGKGTKKKFELFVLDPAGDWYYRWLFVIAMPVLYNWCLLVARACFSDLQRGYFLVWLVLDYFSDVVYIADLFIRLRTGFLEQGLLVKDPKKLRDNYIHTLQFKLDVASIIPTDLIYFAVGIHNPELRFNRLLHFARMFEFFDRTETRTSYPNIFRISNLVLYILVIIHWNACIYYAISKSIGFGVDTWVYPNITDPEYGYLAREYIYCLYWSTLTLTTIGETPPPVKDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKIDAVKHYMQFRKVSKEMEAKVIKWFDYLWTNKKTVDEREVLKNLPAKLRAEIAINVHLSTLKKVRIFQDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGVTQYALLSAGSCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKDDLMEAVTEYPDAKKVLEERGREILMKEGLLDENEVAASMEVDVQEKLKQLETNMETLYTRFGRLLAEYTGAQQKLKQRITVLEVKMKQNTEDDYLSDGMNSPEPAAAEQP
What is the function of this protein?
Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger.  The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.
What are the official names of this protein?
Cyclic nucleotide-gated olfactory channel, Aorta CNG channel, RACNG, Cyclic nucleotide-gated cation channel 2, Cyclic nucleotide-gated channel alpha-2, CNG channel alpha-2, CNG-2, CNG2.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA2 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YAE1_DEBHA
Sequence: MSSKCNGDCSCTSKVDSGVADKTEMTKNESNDIDDIWGDDDIEELDNSTADIKRMHSKQGYLDGITSAKESSLQDGFDDSFPKGAELGIIVGNILGSLISYDDQELFDQAKSELNISQVLHKRYFDEDLELRSTNDHEVIAKWQNVVQNLENK
What is the function of this protein?
The complex LTO1:YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery.  May be required for biogenesis of the large ribosomal subunit and initiation of translation.
What are the official names of this protein?
Protein YAE1.
What is the protein family that this protein belongs to?
Belongs to the YAE1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: VSPR1_BITRH
Sequence: VIGGAECDINEHPSLALIYSTSMRFHCAGTLLNQEWVSFTMWDKDIMLIRTLCAGVLEGGKDTCLAHPCAQPLLPAFYTKVFDYIPWIK
What is the function of this protein?
Snake venom serine protease that cleaves fibrinogen alpha and beta chains (FGA and FGB), but not gamma chains.  Exhibits fibrinolytic and kininogenolytic.  Preferentially cleaves after Arg and Lys residues.
What are the official names of this protein?
Snake venom serine protease rhinocerase, SVSP rhinocerase, Rhinocerase 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RNPH_MYCBT
Sequence: MSKREDGRLDHELRPVIITRGFTENPAGSVLIEFGHTKVLCTASVTEGVPRWRKATGLGWLTAEYAMLPSATHSRSDRESVRGRLSGRTQEISRLIGRSLRACIDLAALGENTIAIDCDVLQADGGTRTAAITGAYVALADAVTYLSAAGKLSDPRPLSCAIAAVSVGVVDGRIRVDLPYEEDSRAEVDMNVVATDTGTLVEIQGTGEGATFARSTLDKLLDMALGACDTLFAAQRDALALPYPGVLPQGPPPPKAFGT
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: ATG10_ASHGO
Sequence: MLSAEDFSDQVLRLLPLLRRWRRCEHALWDPRARRLQLSVATARNSARFDVRVDLHPLYAVPQLLLRYWEPDPAVSEYEVWKLHFVDPYQLPLWQPGRFSIALDQVPATSGSAYETWYVVNSCDTDANVGPETDNYMLRWFSLYGQLLDENLGFTLAAALVAPCTDQKKA
What is the function of this protein?
E2-like enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy and nucleophagy.  Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5.  ATG12 conjugation to ATG5 is required for proper localization of ATG8 to the preautophagosomal structure (PAS).  Likely serves as an ATG5-recognition molecule (By similarity).
What are the official names of this protein?
Ubiquitin-like-conjugating enzyme ATG10, Autophagy-related protein 10.
What is the protein family that this protein belongs to?
Belongs to the ATG10 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: LOXA_SOLLC
Sequence: MLGQLVGGLIGGHHDSKKVKGTVVMMKKNALDFTDLAGSLTDKIFEALGQKVSFQLISSVQSDPANGLQGKHSNPAYLENFLLTLTPLAAGETAFGVTFDWNEEFGVPGAFVIKNMHINEFFLKSLTLEDVPNHGKVHFVCNSWVYPSFRYKSDRIFFANQPYLPSETPELLRKYRENELVTLRGDGTGKREAWDRIYDYDVYNDLGNPDQGKENVRTTLGGSADYPYPRRGRTGRPPTRTDPKSESRIPLILSLDIYVPRDERFGHLKMSDFLTYALKSIVQFILPELHALFDGTPNEFDSFEDVLRLYEGGIKLPQGPLFKALTDAIPLEMIRELLRTDGEGILRFPTPLVIKDSKTAWRTDEEFAREMLAGVNPVIISRLEEFPPKSKLDPELYGNQNSTITAEHIEGKLDGLTIDEAINSNKLFILNHHDVLIPYLRRINTTTTKTYASRTLLFLQDNGSLKPLAIELSLPHPDGDQFGVTSKVYTPSDQGVEGSIWQLAKAYVAVNDSGVHQLISHWLNTHAVIEPFVIATNRQLSVLHPIHKLLYPHFRDTMNINALARQILINAGGVLESTVFPSKFAMEMSAVVYKDWVFPDQALPADLVKRGVAVEDSSSPHGVRLLIDDYPYAVDGLEIWSAIKSWVTDYCSFYYGSNEEILKDNELQAWWKEVREVGHGDKKNEPWWAEMETPQELIDSCTTIIWIASALHAAVNFGQYPYAGYLPNRPTVSRKFMPEPGTPEYEELKKNPDKAFLKTITAQLQTLLGVSLIEILSRHTTDEIYLGQRESPEWTKDKEPLAAFERFGNKLTDIEKQIMQRNGNNILTNRTGPVNAPYTLLFPTSEGGLTGKGIPNSVSI
What is the function of this protein?
Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.  It catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure.
What are the official names of this protein?
Linoleate 9S-lipoxygenase A, Lipoxygenase A.
What is the protein family that this protein belongs to?
Belongs to the lipoxygenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MANBB_ASPFN
Sequence: MAAFSQYPLSTGWSFKDSDDQSPEAWMPVPVVPSVAHQDLQANQKLKNPYIGFNELDARWVNDKSWTYRTVFQKPAVAAGSSIILAFDGLDTFATVKLDGSVILQSDNMFLAHRVDVTKALEAEGDHVLEIDFDCAMRRARELREKDTKHNWASFNGDPARMAVRKAQYHWGWDWGPLLSTAGIWREVRLEVYSAKISDLWTEVELASDHQTARVSAFTEVDAADSVDSYKASFLLSLHGKEVAREVATLKDKVAKVTFDVTQPSLWWPNGYGDPALYEISVSLEKEDCEIHSVSKKIGIRTAELIQQPDRHGKSFFFRINGVDVFCGGSCWIPADNLLPSITAERYRKWIELMVAGRQVMIRVWGGGCYEDDSFYQACDELGVLVWQDFMFGCGNYPTWPELLESIEKEANYNVRRLRHHPSIVVYVGNNEDYQVQESAGLVYDYEDKNPENWLKTDFPARYIYEKLLPSVVEKLSPKTVYHPGSPWGDGKITSDPTVGDMHQWNVWHGTQEKYQIFDTLGGRFNSEFGMEAFPHMSTIEYFVENEADKYPQSHVLDFHNKADGHERRIATYLVENLRTATDLETYVYLTQVVQAETMMFGYRGWRRQWGDERHCGGALLWQLNDCWPTISWAIVDYFLRPKPAFYAVARVLKPIAVGVRREHHDWSVTHAQPPKTSKYELWIASSLQKETVGTIELRFLSVNTGLDVRAPILRDNVKIVPNGTTNILEGVINHKAQPEPHVLAARLWVDGEVTARDVDWPQPFKYLDLSDRGLEVNKVSESGNEQKLLITAKKPVKCLVFEERDGIRVSDSAMDIVPGDGQTVTVTGLKAGDAPLKYKYLGQ
What is the function of this protein?
Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of beta-mannosidic oligosaccharides of various complexity and length.  Prefers mannobiose over mannotriose and has no activity against polymeric mannan.  Is also severely restricted by galactosyl substitutions at the +1 subsite (By similarity).
What are the official names of this protein?
Beta-mannosidase B, Mannanase B, Mannase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family. Beta-mannosidase B subfamily.
Protein: BETA_PHOPR
Sequence: MNTTYDYIIVGAGSAGCVLADRLSASGEHYILLLEAGGSDRSIFIQMPTALSYPMNSEKYAWQFETQPEAGLDSRSLHCPRGRVLGGSSSINGMVYVRGHACDYDEWVEQGAEGWSYQECLPYFRRAESWIHGEDTYRGGDGPVGTCNGNDMELNPLYQAFIDAGQQAGYPKTDDYNGYQQEGFGPMHMTVDKGIRASTSNAYLRRAMKRSNLTVRKGVVTRKVLIKNKQAIGVEIEVGGKVQSVYANTEVLLSAGSVGSPQLLQLSGIGPKAVLEQAGIAVKHDLPGVGENLQDHLEVYFQYACHQPITLNSKLGLISKGLIGTRWILQKDGLGATNHFESCAFIRSRAGLKWPNIQYHFLPAAMRYDGQAAFDGHGFQVHVGPNKPQSRGRIWITSADPHQKPNIEFNYISTEQDKQDWRDCIRLTREILAQPAMDDYRGEEIQPGADITSDEAMDAWVRQNVESAYHPSCTCKMGSDNDPMTVLNKDCQVRGIDSLRVIDSSVFPTIPNGNLNAPTIMVAEKAADAILGNTPLSPSNAPTWIAPQWETEQRNGAAQRPMFHQQRK
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: RL17_DESAP
Sequence: MGYRRLGLRSDHRRAMLRNMVTSLIKEERITTTETRAKEVRSIAEKMVTLAKRGDLAARRQVSEYLFDEEAAKKLFNTVAARYKDRPGGYTRIVKVGFRRGDAAPMVILELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.