PharMolix/UniProtQA huggingface dataset:
Protein: ACH8_CAEEL
Sequence: MTLKIAFFTLILLVSIERVYSSDEEYRLLKDLREGYDPVERPVADHRKPVNVKLRLILQQLVDVDERNQVITLVVWNQYTWNDYKLRWSPEEYGNITTLQIPHGTLWKPDILLFNSANEHFDASFPVHMVVSSNGDVLFAPPGIVSFSCSLSMTWFPYDQQVCYLKFGSWTYGKKLDLQIDDSDLPDGHKMDLQYYIPNGEFDLLATPAFRKSTTFLDETYVELYFHMHLKRRTMYYGLNWIVPSILISLSNILGFTMPPECGEKITLQITNFLSVMVFLAMVSEVAPPTSESIPIIAAFFSLSIVILGLSICASLIIVNIFFRHPKTHRMGDWTRYVFLEWLPWFLLMSRPEHTFCRPRREEEKNDEEAGGDGTKLLENQQHQPRPRLLVNSQLVMDSTVPYLEEIIGYLKVFKAKLDDDEEEEEEILNWRFMAMVIDRLSLFLFTGLIFGTTALIFAFCPNLFTDSPIVDIE
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (By similarity).  Nicotinic acetylcholine receptor in the MC pharyngeal motor neuron involved in pharyngeal pumping (PubMed:15020415, PubMed:8601480).  Has a role in the determination of life span possibly via calorific restriction which affects growth rate, although this is independent of metabolic activity (PubMed:8462849, PubMed:9789046, PubMed:15141086, PubMed:28853436, PubMed:30965033).  Plays a role in the defense against the accumulation of ingested live pathogenic bacteria in the intestine (PubMed:30965033).
What are the official names of this protein?
Neuronal acetylcholine receptor subunit eat-2, Abnormal pharyngeal pumping eat-2.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=MC motor neuron.
Protein: IL1RA_CANLF
Sequence: METCRCPLSYLISFLLFLSHSETACRPLGKRPCRMQAFRIWDVNQKTFYLRNNQLVAGYLQGSNTKLEEKLDVVPVEPHAVFLGIHGGKLCLACVKSGDETRLQLEAVNITDLSKNKDQDKRFTFILSDSGPTTSFESAACPGWFLCTALEADRPVSLTNRPEEAMMVTKFYFQKE
What is the function of this protein?
Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A.  Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
What are the official names of this protein?
Interleukin-1 receptor antagonist protein, IL-1RN, IL-1ra, IRAP, IL1 inhibitor.
What is the protein family that this protein belongs to?
Belongs to the IL-1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: YOBD_ECO45
Sequence: MTITDLVLILFIAALLAFAIYDQFIMPRRNGPTLLAIPLLRRGRIDSVIFVGLIVILIYNNVTNHGALITTWLLSALALMGFYIFWIRVPKIIFKQKGFFFANVWIEYSRIKAMNLSEDGVLVMQLEQRRLLIRVRNIDDLEKVYKLLVSTQ
What are the official names of this protein?
UPF0266 membrane protein YobD.
What is the protein family that this protein belongs to?
Belongs to the UPF0266 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: METK_BORBU
Sequence: MNKIIAANQTLTSEAVSEGHPDKIADQISDAILDEILKEDKNAKVACEVIIAQNLVVIAGEINSPVKKNIDIKEVAKNIIKDIGYTNIDYGLDYKTITVIDAIGNQSRDIINAIEKKGSNALGAGDQGIIFGYACDETKNFLPAPYELANSILKKASNLRKSGAIKWLRPDSKSQVTIEYDKNRNPVKIKNIIVSHQHHPNISQKLIQQTIIEEIIKPTVQDKSMLDENTAYCINPSGNFVIGGPTGDTGLTGRKIIADSYGGFARHGGGAYSGKDATKVDRSAAYMARYIAKNMVAAGISKEFELQLAYAIGIENPISIQITGGINDPKYANKILNFIVNNFDLTPNGIIEKLKLKQPIYLKTCTYGHFGKNEFEWEKLDFVKKIQTALKK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTS3B_STRMU
Sequence: MDYSKVASEVITAVGKDNLVAAAHCATRLRLVLKDDSKVDQKALDKNADVKGTFKTDGQYQVIIGPGDVNFVYDEIIKQTGLTEVSTDDLKKIAASGKKFNPIMALIKLLSDIFVPIIPALVAGGLLMALNNFLTSEGLFGTKSLVQQFPIIKGSSDMIQLMSAAPFWFLPILVGISAAKRFGANQFLGASIGMIMVAPGAANIIGLAANAPISKAATIGAYTGFWNIFGLHVTQASYTYQVIPVLVAVWLLSILEKFFHKRLPSAVDFTFTPLLSVIITGFLTFIVIGPVMKEVSDWLTNGIVWLYDTTGFLGMGVFGALYSPVVMTGLHQSFPAIETQLISAFQNGTGHGDFIFVTASMANVAQGAATFAIYFLTKDKKMKGLSSSSGVSALLGITEPALFGVNLKYRFPFFCALIGSASAAAIAGLLQVVAVSLGSAGFLGFLSIKASSIPFYVVCELISFAIAFAVTYGYGKTKAVDVFAAEAAVEEAIEEVQEIPEEAASAANKAQVTDEVLAAPLAGEAVELTSVNDPVFSSEAMGKGIAIKPSGNTVYAPVDGTVQIAFDTGHAYGIKSDNGAEILIHIGIDTVSMEGKGFEQKVQADQKIKKGDVLGTFDSDKIAEAGLDNTTMFIVTNTADYASVETLASSGTVAVGDSLLEVKK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in sucrose transport.
What are the official names of this protein?
PTS system sucrose-specific EIIBCA component, EIIBCA-Scr, EII-Scr.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL4_MORMO
Sequence: MELVMKDAQSLTVSETTFGRDFNEALVHQVVVAYAAGARQGTRAQKTRAEVTGSGKKPWRQKGTGRARSGSIKSPIWRSGGITFAAKPQDHSQKVNKKMYRGALKSILSELVRQDRLIIVEKFAVEAPKTKLLVQKLKDMALEDVMIVTHEVDENLFLAARNLYKVDVRDVTAIDPVSLIAFGKVVMTAEAVKQVEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: LON_SOLUE
Sequence: MLTSKEKSDTKRLPMMPIRDVVIFPYMMTPFVVGRESSVRALEEAMAGDKKIFLATQHDASIDEPKPNEIYSVGTIVNIVQSLKLPDGNIKVLVEGVERAKVVSVADDEGFFRATVRTSGFKVETGPQLDALISRVTTLFEQYVKLSQNLNYETMVAAIRVDEPGKLADTVGANLQLTIEEKQELLEIFDPIDRLTRVAEMLDIEIEKLNVDRTIQGRVKRQMEKAQKEYYLNEKIKAIQKELGRGEKSEIDELKRRIEEAGMTADAQEKAMAELKRLENMPPMSAESTVSRNYLDWLLAVPWKKKSKEIRDLKFAEGVLEADHYGLEKIKERILEFLAVRRLVKNPKGSILCFVGPPGVGKTSLGMSIAKATGRKFVRMSLGGVRDEAEVRGHRRTYIGALPGQIIQMMKKAGTRNPVFMLDEVDKMSMDFRGDPSAALLEVLDPEQNFMFVDHYLDVEYDLSQVFFVATANVMHTIPAALQDRMEVIRLSGYTELEKMEIAKRFLVKKQIEATGLDSKQIDFQDDGINSLIQYYTREAGVRNLEREIGNVCRKVARQVVNAESGKDKKAPAKAVINGDKVPELLGPWKFRDLVVEKKNEIGAATGLAWTEVGGQLLTVECTLMEGKGKLTITGKLGEVMQESAQAAMSYIRSRAMSLGIPRDFYRNLDLHIHIPEGAIPKDGPSAGITLATTICSALTKIPVRGDLAMTGEITLRGKVLPIGGLKEKLMAAHRHGILEAIMPKENEKDLPDIPDAIKKTMKLHFVESMDEVLKIALEREIVALPIPGAELPVEAGKPAEETVAH
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CITD2_SALTI
Sequence: MKIIKDALAGTLESSDVMIRIGPSSEPGIRLELESLVKQQFGAAIEQVVRETLAKLGVERALVSVDDKGALECILRARVQAAALRAAEQTEIQWSAL
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein 2, Citrate lyase gamma chain 2.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEM5A_RAT
Sequence: MKGACILAWLFSSLGVWRLARPETQDPAKCQRAEHPVVSYKEIGPWLREFRAENAVDFSRLTFDPGQKELVVGARNYLFRLQLEDLSLIQAVQWECDEATKKACYSKGKSKEECQNYIRVLLVGGDRLFTCGTNAFTPVCTIRSLSNLTEIHDQISGMARCPYSPQHNSTALLTASGELYAATAMDFPGRDPAIYRSLGTLPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEHDCGKTVFSRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPELDLIYGIFTTNVNSIAASAVCVFNLSAISQAFNGPFKYQENSRSAWLPYPNPNPNFQCGTMDQGLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGRDTLVHIIYLATDYGTIKKVRAPLSQSSGSCLLEEIELFPERKSEPIRSLKILHSQSVLFVGLQEHVVKIPLKRCHFHQTRGACIGAQDPYCGWDAVMKKCTSLEESLSMTQWDQSVPTCPTRNLTVDGSFGPWSPWTPCTHTDGTAVGSCLCRSRSCDSPAPQCGGWQCEGPRMEITNCSRNGGWTPWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHVFWTGWGPWERCTAQCGGGIQARRRTCENGPDCAGCNVEYQPCNTNACPELKKTTPWTPWTPVNISDNGGHYEQRFRYTCKARLPDPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSAHTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEFQECNILPCPVDGVWSCWSSWSKCSATCGGGHYMRTRSCTNPAPAYGGDICLGLHTEEALCNTQTCPENWSEWSEWSVCDASGTQVRTRQCILLFPVGSQCSGNTTESRPCVFDSNFIPEVSVARSSSVEEKRCGEFNMFHMMAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVSPAALNSSITNHINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYFTDLNNYDEY
What is the function of this protein?
Bifunctional axonal guidance cue regulated by sulfated proteoglycans; attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs).  Ligand for receptor PLXNB3.  In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1.  May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis.
What are the official names of this protein?
Semaphorin-5A, Semaphorin-F, Sema F.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SECF_ECOLI
Sequence: MAQEYTVEQLNHGRKVYDFMRWDYWAFGISGLLLIAAIVIMGVRGFNWGLDFTGGTVIEITLEKPAEIDVMRDALQKAGFEEPMLQNFGSSHDIMVRMPPAEGETGGQVLGSQVLKVINESTNQNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVYVGFRFEWRLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVSDRIRENFRKIRRGTPYEIFNVSLTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLTMLIGVSIGTASSIYVASALALKLGMKREHMLQQKVEKEGADQPSILP
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.  The large periplasmic domain is thought to have a base and head domain joined by a hinge; movement of the hinge may be coupled to both proton transport and protein export, with the head domain capturing substrate, and a conformational change preventing backward movement and driving forward movement.  Expression of V. alginolyticus SecD and SecF in E. coli confers Na(+)-dependent protein export, strongly suggesting SecDF functions via cation-coupled protein translocation.
What are the official names of this protein?
Protein translocase subunit SecF, Sec translocon accessory complex subunit SecF.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL17_DEHMC
Sequence: MRHKVSGRRFDRPTGQRMSLYRNLVTDLLNYEEITISEPRAKEIRSMAEKMITLGKKGTLASRRRALAFVYMPGIVEKVFEDLSKRYAERPGGYTRMTKLGPRQGDGAEMVKLELIK
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: ENTB_ECOLI
Sequence: MAIPKLQAYALPESHDIPQNKVDWAFEPQRAALLIHDMQDYFVSFWGENCPMMEQVIANIAALRDYCKQHNIPVYYTAQPKEQSDEDRALLNDMWGPGLTRSPEQQKVVDRLTPDADDTVLVKWRYSAFHRSPLEQMLKESGRNQLIITGVYAHIGCMTTATDAFMRDIKPFMVADALADFSRDEHLMSLKYVAGRSGRVVMTEELLPAPIPASKAALREVILPLLDESDEPFDDDNLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAWWKLLSREVK
What is the function of this protein?
Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine.  The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms.  EntB is a bifunctional protein that serves as an isochorismate lyase and an aryl carrier protein (ArCP).  Catalyzes the conversion of isochorismate to 2,3-dihydro-2,3-dihydroxybenzoate (2,3-diDHB), the precursor of 2,3-dihydroxybenzoate (DHB).  In the enterobactin assembly, EntB functions as an aryl carrier protein phosphopantetheinylated near the C terminus by EntD to yield holo-EntB, which is then acylated by EntE with 2,3-dihydroxybenzoyl-AMP to form DHB-holo-EntB.  Then this product will serve in the formation of the amide bond between 2,3-dihydroxybenzoate (DHB) and L-serine.
What are the official names of this protein?
Enterobactin synthase component B, Enterobactin biosynthesis bifunctional protein EntB, Enterochelin synthase B.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the isochorismatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACKA2_ALIF1
Sequence: MNNEYVLVINSGSSSLKFAVIDSVSGDAVLSGLGECFGLEDARMSWKYQGQKTEIAIEGNENHHKIAIGKLVGLTEELGFTDGIVAIGHRIVHGGEKFTKTVRINEEVTKEIESLSDLAPLHNPAGAIGIRAAVEAFPSLPQFAVFDTAFHQTMPKRAYTGAIAKELYTDFGVRRYGFHGTSHYFVSREAAKMINKPIEESNFISVHLGNGASVCAIKDGNSVDTSMGFTPLSGLMMGTRCGDLDPGIIEYLLKKGWSQEQVFNSLNKESGFLGVSGLTSDARGILEAMEEGHEGATLAFQVFTYRVAKYVASYLAALDSLDGIIFTGGIGENSLPIRREILSNLKILGFVEDVAGNEGARFGADGIIAKSEMLNAVAMVIPTNEEFVIAQQSVELL
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase 2, Acetokinase 2.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTNS_DROME
Sequence: MDFSTHRLTTLLLLLLATVALGNAQSSQLTVDSHDITVLLNSNETFLVFANGLLDSDVEVALGTDSEDHLLLDPATFVYPAGSTRNQSVVITGLKAGNVKVVADSDDANKEIVKDVFVRVTVAKSRALIYTSIIFGWVYFVAWSVSFYPQIWSNYRRKSVEGLNFDFLALNIVGFTLYSMFNCGLYFIEDLQNEYEVRYPLGVNPVMLNDVVFSLHAMFATCITILQCFFYQRAQQRVSFIAYGILAIFAVVVVVSAGLAGGSVIHWLDFLYYCSYVKLTITIIKYVPQALMNYRRKSTSGWSIGNILLDFTGGTLSMLQMILNAHNYDDWVSIFGDPTKFGLGLFSVLFDVFFMLQHYVFYRHSRESSSSDLTTVTDVQNRTNESPPPSEVTTEKY
What is the function of this protein?
Cystine/H(+) symporter that mediates export of cystine, the oxidized dimer of cysteine, from lysosomes.
What are the official names of this protein?
Cystinosin homolog.
What is the protein family that this protein belongs to?
Belongs to the cystinosin family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.
Protein: Y1242_METJA
Sequence: MEGGAMMLLEVKNVTKKFGDKVVLKNISFTLEEGESLGILGKSGAGKSVLLHMLRGMDGYEPTEGQIIYHVSYCEKCGYVDVPSKAGTPCKKCGNELKKIEVDFWNDKKYTYNLKRKIAIMLQRTFALYGEKTVLENILEALHQAGYEGKEAIDMALKLIKMVKLEHRITHIARDLSGGEKQRVVLARQIAKEPFIFLADEPTGTLDPQTAKLVHSALKELVIKNKISLILTSHWPEVIAELTEKAIWLDKGEIIMEGTSEEVVNKFMETVKEFKKPETEVEIKEDIIKLENVSKHYCSVERGVIKAVDNVTLNIREREIFGLVGTSGAGKTTLAKIIAGVLPPSKGKYWFRVGDEWVDMTKPGPMGRGRAKRYIGILFQEYALYPHRTILENLTEAIGLELPDEFARMKAVYTLVSVGFSEEEAEEILDKYPHELSVGERHRCALAQVLIKEPRVVILDEPTGTMDPITRNTVAESIHKSRIELEQTYIIVSHDMDFVLNVCDRAGLMRNGKLIKVGKPEEIVALLTEEEKQEMFGQK
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein MJ1242.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: BRK4_PHAJA
Sequence: RPPGFTPF
What is the function of this protein?
Produces in vitro relaxation of rat arterial smooth muscle and constriction of intestinal smooth muscle (By similarity).  May target bradykinin receptors (BDKRB).
What are the official names of this protein?
Des-Arg9-[Thr6]-bradykinin, Des-Arg-[Thr6]-bradykinin.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-related peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: FABH_STAAT
Sequence: MNVGIKGFGAYAPEKIIDNAYFEQFLDTSDEWISKMTGIKERHWADDDQDTSDLAYEASLKAIADAGIQPEDIDMIIVATATGDMPFPTVANMLQERLGTGKVASMDQLAACSGFMYSMITAKQYVQSGDYHNILVVGADKLSKITDLTDRSTAVLFGDGAGAVIIGEVSDGRGIISYEMGSDGTGGKHLYLDKDTGKLKMNGREVFKFAVRIMGDASTRVVEKANLTSDDIDLFIPHQANIRIMESARERLGISKDKMSVSVNKYGNTSAASIPLSIDQELKNGKIKDDDTIVLVGFGGGLTWGAMTIKWGK
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPS_BURTA
Sequence: MAIIPDKQDSTVLERKEQKLKPPSMYKVVLLNDDFTPMEFVVMIVQEYFKKDRETATQIMLKVHREGRGVCGVYTRDIASTKVEQVVTHARQAGHPLQCVMEEA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: NOC_BACC1
Sequence: MKNTFSRLFGFGDKESEFELQDESHEEIDKKVYEEIQEIPIVNITPNRYQPRTVFDDARIEELALTIRTHGLIQPIVVRQYEDDKYEIIAGERRFRAATKLGWEKVPAIIKNLNDTETASVALIENLQREELTAIEEAVAYQKLIELHNLTQEALAQRLGKGQSTIANKLRLLKLPEEIKNALLEKSITERHARALIPLKNEELQLKVLQEIVEKQLNVKQTEERIAKLLEEAKPKRKAKQKAVSRDTRIAMNTIRQSLQMVADSGLNVNSEEEEFDEYYQITIQIPKKK
What is the function of this protein?
Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle.  It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage.
What are the official names of this protein?
Nucleoid occlusion protein, Noc.
What is the protein family that this protein belongs to?
Belongs to the ParB family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: SYN_BACCZ
Sequence: MENTLVKSLYRDTDKYAGQTVQVSGWIRNLRDSKAFGFIELNDGSFFKSVQIVFDTELDNFKEIAKLPLSSSVKVEGKVIATPGAKQPFEIKAEKIDIEGLSDSDYPLQKKRHTFEYLRTIAHLRPRTNAFSATFRVRSIAAFAIHQFFQERGFVHVHTPIITGSDTEGAGEMFRVTTQDLNNVPKGEDGQVDESKDFFGKETNLTVSGQLNAEAYALAFRDVYTFGPTFRAENSNTTRHAAEFWMVEPEIAFAELGDVMNLTEDMLKYAMKYVLEHAPEEMEFFNSFVDKTVLERMNNVINSDFGRITYTEAIKVLQESGADFKYPVEWGIDLQTEHERYLSEEIFKRPVFVTDYPKDIKAFYMRLNDDGKTVAATDLLVPGIGELIGGSQREERMDVLVDRIKELGMNEEDYWWYLELRKYGGTKHAGFGLGFERFLMYITGMANIRDVIPFPRTPGSSEF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_VIBAL
Sequence: SFKSDEAKQELADLNADLMVFVAYGMLLPQAVLDTPKLGCINVHGSILPRWRCAAPIQRSIWAGDAETGVTIMQMDIGLDTGDMLKIATLPIETTDTSASMYEKLAELGPEALIDCLADIAAGKAVPVKQDDELANYAKKLSKEEARINWNDDAAHIERCVRAFNPWPMSHFEAAENSIKVWKAVWQSKPVTTSGTIVQADKTGIYVVTGNGVLVLEQLQVPGKKAMSVQDILNSRAAWFEVGTLLV
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: Y2183_ARCFU
Sequence: MTLLSINYEKFKYIEVPELLSKLGVVFMRGYVVGLVLALMLVTAPAMAEDFSMNGTEFAAAFIKNTVSNLDLGAKFLHLLYEVNDTDTNSNLFQNLWGLVYGGVLVAGWNNQVTAEVLETLADSDNLTSQRTNISESIRMMATNTSVVFGDTEGSQGLAALMKYQVKALQNTSITTTNSTGVEVPLVEAYAEALANTITDNVKFMMELFKAIPNALT
What are the official names of this protein?
Uncharacterized protein AF_2183.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GLYA1_PSEPF
Sequence: MSLQNFDPAIARLIDRERNRQETHLELIASENYVSEEVLQAQGSLLTNKYAEGYPGRRYYGGCKVVDEIENLAIERARKLFGCEYVNVQPHSGSQANQAVFLAVLEPGDRILGMSLAHGGHLTHGASVNFSGKFFQAFTYGLEKDSETLDYDQMEDLAREHRPKMIIAGASAYSRVIDFPRFRKICDEIGAYLMVDMAHYAGLIAAGVYPSPVGIADFITSTTHKTLRGPRGGLILAKAEYAAVLDKTIFPVYQGGPLMHVIAAKAVAFNEALGDEFKHYQQRVINNARTMADVLTRRGLRVVSGGTDCHMFLLDLRAMNITGKDAEALLESAHITLNKNAIPDDPQKPAITSGIRIGTPALTTRGFGEAECAEVANLIADLLEQPDNTARVENIRRRVMHLCECFPVYLLT
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase 1, SHMT 1, Serine methylase 1.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INS_CAMDR
Sequence: FANQHLCGSHLVEALYLVCGERGFFYTPKAGIVEQCCASVCSLYQLENYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
What are the official names of this protein?
Insulin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: AMPP1_ARCFU
Sequence: MIFKAVRVPFKSGRFAVILNEEDASELGVREGDRVRVRYGKAGVVATVQITREIVEKGFVGLTDLASMELGISDGAEVDVFPSPKPKSVELIKKKTRGEKLSQDEIRRIVEDITNNALSEVELTAFVISSMLRGMDFDEIEWLTRSMIETGERIEFDRGTVVDKHSIGGVPGNKISLLIVPTVAAAGLLIPKTASRAITSASGTADTMEVLANVNLSVDEIKEITERVGGVIAWGGATNIAPADDKIIRVEHPLSIDPRPQLLASVMAKKGSVGAKHVVIDIPVGEGAKIEKVEVGRSLANDFIELGRRLGLNVMAAITYGGQPVGRAIGPALEAREALKTMEDRRGPSSLVEKSLGIAGILFEMTGIATNGYQHARKIFESGKTLEKFREIVAAQGGDESVKAEDVAVGDKTYTLTSQVEGAVVSVNNKSIVKIARTAGAPKDKGAGVYVHKKRGEVVKVGDPLLTIYAEKEWKLDNAIEVANTERPIVVSGMVLEVYGRRGV
What is the function of this protein?
Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P).  Exhibits phosphorylase activity toward CMP and UMP in addition to AMP.  Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO.
What are the official names of this protein?
AMP phosphorylase 1, AMPpase 1, Nucleoside monophosphate phosphorylase 1, NMP phosphorylase 1.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
Protein: INX8_CAEEL
Sequence: MFSVPFLTSLTSHLGITAIDDASDTLSCLITAFLFITAAILTSAKTYVGSAMECWLPQTYSGDWGEFAENYCFLKDTYFYPRQQSMTDIPMYHKERHRLTYYQWSSMYLAVAGIAFMIPKFLWRLSQSTTDMPVVYFCDTANEIKNETEDKRSAKIKEMARFMRTKITSVHTPSLFSFIRMYMVYSVIKILYLVNAIAQFVIIAIFLGQKRNLFWGWTLFMNLLNGITWETTGLFPRVTFCDFQVREMAGNNRDETVECVIGINEFNEKIFLFFWFWLVFLVFSTLIAHFYNAAQIVKPYFIHSLLFAIRDHDIVDQKELFREFGEKYLTMDGKLILSFVKSQSDLVASEVAVEMYSDFLEARDRANIAEDKYNNILKNGKQ
What is the function of this protein?
Structural component of the gap junctions.
What are the official names of this protein?
Innexin-8, Protein opu-8.
What is the protein family that this protein belongs to?
Belongs to the pannexin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.