PharMolix/UniProtQA huggingface dataset:
Protein: HSDL2_XENTR
Sequence: MLPNTGKLAGCTLFITGASRGIGKAIALKAARDGANVVIAAKTAEAHPKLPGTIYTAASEIEAAGGKALPCIVDVRDENQISAAVEKAVDTFGGIDILVNNASAISLTNTLETPMKKVDLMMGINTRGTYLTSKICIPYLKKSKVAHILNLSPPLNLNPIWFKNHCAYTIAKYGMSMCALGMSEEYKGEIAVNALWPKTAIHTAAMDMLGGSGVDKQCRTPDIMADAAYAILSKPKDFTGNFVIDEELLKHEGIKDLDVYAVSPGHPLLPDFFLDESPEALASAMEEHGATAAFKAGKAQAKSQDSSPLQETFKAIESLVNEEAVKTTQGIYQFVLSGEESGNWFLDLKNGKGGVGSGEPSTKADVVMSMDSGDFIKMFTGKMKPTMAFMSGKLKIKGDMGLALKLEKILGQMNAKL
What is the function of this protein?
Has apparently no steroid dehydrogenase activity.
What are the official names of this protein?
Hydroxysteroid dehydrogenase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: ATPH_OENAR
Sequence: MNPLISAASVIAAGLAVGLASIGPGIGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PFKA_BUCCC
Sequence: MIKKIGILTSGGDSPGMNAIIRSVVCTALNHNIEVKGIYNGFLGLYNNDMKLLKYSHVANLLNQGGTILGSSRFLEFKLEKTRKIAIKNIYKRKIDCLIIIGGDGSYKAANFLTNMGVPCIGIPGTIDNDVSGTDYTVGYFTALETVVDAIDKLRDTSASHHRISIIEIMGRYCGDLTLSAAIAGGCEFIVIPEIIYQKELLLLEIQKSIKKGNKHSIVAITEHICDVNKLAKYIQKKTFKETRATILGHIQRGGKPVAYDRILASRMGIYAIQLLLKGYKGQCIGVINNKIVHHNINYALKNMKKIFKKDLLNSIKKIY
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSXB_SHIB3
Sequence: MNAIWIAVAAVSLLGLAFGAILGYASRRFAVEDDPVVEKIDKILPQSQCAQCGYPGCRPYAEAISCNGEKINRCAPGGEAVMLKIAELLNVEPQPLDGEAQELTPARMVAVIDENNCIGCTKCIQACPVDAIVGATRAMHTVMSDLCTGCNLCVDPCPTHCISLQPVAETPDSWKWDLNTIPVRIIPVEHHA
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rsx electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: COAX_PARXL
Sequence: MTSGAPCLLIDAGNSRIKWALVQAGGSQIASGALTHGGEHQPDWLSLPTPGGAWLSNVAGESVARRIAALLEARWPQLPLTTISACAQQCGVTNSYTAPHMLGSDRWAGLIGAHAAFPGEHLLIATFGTATTLEALRADGCFVGGLIAPGWTLMMRSLGEHTAQLPTLDASAARGLLDGSTRDAARRGPFFATDTPRSLSAGCTLAQAGLVERMWRDLQDEWQVPVRLVVSGGAVDEVASALKVPHTRHDSLVLSGLALIAAGRAAERGA
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG3_KLULA
Sequence: MLRSTLSNWREYLTPISHTSTFETSGQLTPEEFVKAGDYLVHMFPTWKWNGNDFQNVHHKDFLPNDKQFLVTKKVPCKLRANNYLELDDTETKDVGDGWALQEEHSQDSERKSTNNADDSELPEELEELHIVDDGDDEEYDDQLYDNEFADDDIVDIRPSTLRFYDLYITYSTSYRVPKMYLCGYDNDGTPLSPDQMFEDIAADYRSKTATIEPLPFLKGNNISVSIHPCKHANVMKVLMEKVRSSRSRARKVDPQTTDEDWEDLQSDVDDGLRVDQYLVVFLKFITSVTPGIEHDYTMEGW
What is the function of this protein?
E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8.  The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8 from ATG3 to phosphatidylethanolamine (PE).  This step is required for the membrane association of ATG8.  The formation of the ATG8-phosphatidylethanolamine conjugate is essential for autophagy and for the cytoplasm to vacuole transport (Cvt).  The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy (By similarity).
What are the official names of this protein?
Autophagy-related protein 3, Autophagy-related E2-like conjugation enzyme ATG3.
What is the protein family that this protein belongs to?
Belongs to the ATG3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPZ6C_ORYSJ
Sequence: MESCARRCAVSGLTALSMRLTKQLSAAAASKAGAAGNLVFSPLSIYSVLSVVTAGARGRTLTELLGALGAESREKLAANAGEMARALPAPGGGAAQPGGGPRVAHACGVWHERTRTVRPAFRDAAAASFNAAALAVDFLNNPEEARKEINSWVAAATENLIDTILPPGSVSTDTGLVVTSAIYFNGQWWTPFCKEITEKRAFHRLDGGDVEADFMRSGEDQYIAVHDGFKVLKMPYAACVSARTTTTPRYSMYVFLPDERDGLWSLEDRMAAGGEGFLREHTPERRVEVGEFRIPRFKLSFDDSVVGALQRLGVRDVFKPFVADLADVLEAENSGDDPPLFVSDVKHKAVIEVNEEGTEAAAATAVCLTFASAAPSSRRPARVDFVADHPFAFLVLEESSGAVLFAGHVVDPTDE
What is the function of this protein?
Probable serine protease inhibitor.
What are the official names of this protein?
Putative serpin-Z6C, OrysaZ6c.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
Protein: BIOB_ALISL
Sequence: MEVRHNWTVVEVKALMDKPFMDLVFEAQLVHRQYQEANYVQVSTLLSIKTGACPEDCKYCPQSAHYRTDVDRERLMEVESVLDAAKKAKDSGSTRFCMGAAWKNPKERDMPYLLDMIKGVKDIGLETCMTLGMITSDQAGELSGAGLDYYNHNLDTSPEFYGNIITTRTYQDRLDTLSHVRDAGMKICSGGIIGMGESVNDRAGLFVELANLPQHPESVPVNMLVKVKGTPLEDAEDVDPFDFIRLIAVARIMMPESAVRLSAGRESMNEQMQALCFMAGTNSVFYGCKLLTTPNPDEDSDMQLFKKLGVNSHQVAQKPDEVQEHELLDRVAERVASRPDKNDLFYEASV
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: RL13_CLOP1
Sequence: MKSYIAKAQEVERKWYVVDAAGKPLGRVASQVASILRGKNKPTFTPNVDCGDFVIVINAEKVVLTGKKLDQKMLRKHSLYAGGLKETPYREVLEKKPEFAFEEAVRRMLPTGVLGRKMLKKLNVYRGAEHDHAAQKPEVLELRY
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: DNAJ_ACIAC
Sequence: MSKRDFYEVLGVPKNASDEEIKKAYRKLAMKHHPDRNQGDAAKPAEEKFKEAKEAYEMLSDPQKRAAYDQFGHAGVDPNMRGPGGAGAEGFGGFAEAFGDIFGDMFGGRRGAGGGRQVYRGNDLSYAMDITLEEAAKGKEAQIRIPSWENCETCHGSGAKPGTSAKTCTTCSGTGTVQMRQGFFSVQQTCPHCRGTGKIIPEPCVTCHGQGKVKKQKTLEVKIPAGIDDGMRIRSVGNGEPGTNGGPPGDLYIEIRLKKHEIFERDGDDLHCQVPVSFITAALGGEIEVPTLQGKAAIDIPEGTQAGKQFRLRGKGIKGVRASYPGDLYCHIVVETPVKLTEHQRKLLRELDDSLKKGGGKHSPSGESWTDRLKNLFT
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOD2A_XENLA
Sequence: MASLGVILFFVIASLIHGKPIHSERKAAKIPLEGSNLGYKKPNNIYGSRLSQGMRYPPSMMQLYQTLILGNDTDLSILEYPVLQESDAVLSLIAKSCVVVGNRWTLSFDMSSISSSNELKLAELRIRLPSFERSQDVTVEIYHTKEGQENLFMGSFKTNPSVAMGSSWKIFNLTRMLQYYLHQGEPFTNVEYIEVKNMHERAKPHVIKRGVRAEVEEGLQRNKDNTPASSFPTERVVLVVFTRDKPTASHFGSPSLIHTVESSKYVMSENTVRVTDTRRPRRNQKTKNTIVMNTIPSRSVGKTLCRRVDMIVDFEKIEWGDRIVYPKRFNAYRCEGACPIPLNETFKPTNHAYIKSLVKLYDQEKVECSSCVPVKMSPLSMLLYEDGEVVLKHHEDMIVDECGCN
What is the function of this protein?
Cooperation and regulatory loops of multiple nodals are essential for mesendoderm patterning in early embryos.  Essential for mesoderm formation and axial patterning during embryonic development.  Activates the activin-like signaling pathway to induce dorsal and ventral mesoderm in animal cap ectoderm.  In addition, also dorsalizes ventral marginal zone (VMZ) tissues during gastrulation.  Induces muscle actin.  Appears to act as both a short-range and long-range morphogen.  The unprocessed protein inhibits bmp- and wnt-signaling.
What are the official names of this protein?
Nodal homolog 2-A, Nodal-related protein 2-A, Xnr-2-A, Xnr2-A, nr-2.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
Protein: MRDA_SALTS
Sequence: MTFKDFDAEEKLFLRRVIVAFGVVVVCFGILIFNLYNLQIRQHHYYTTRSNENDIKMLPVAPTRGIIYDRNGIPLVRNVTWYDIAVTPYKIADMDALLKQLTPIVDLSPDDISDFRRALKSSSRYRPVVLKNALTDVEIARFAVNQFHFNGVTINSYQDRQYPYGAELAHVLGYVSKINDNDLKALDKKGLAENYAADHNIGKQGIERYYENDLHGKTGYQEVEVDNHGRIVRLLKDVPPIAGKNIHLTLDLHLQEYIESLLAGQRAAVLVEDPHDGSVLAMVSMPSYDPNPFVKGISYQDYGKLLHDKNLPLINRVTQGLYPPASTVKPYMAMSALLCGIITPQTTFFGAPTWTLPGTQRHYRDWKKTGHGMLDVTKAIEESADTFFYQVAYMMGIDRIDTMLSQFGYGKPTGIDLNEEYDGLLPSRAWKQRVHKKAWYQGDTISVGIGQGYWIATPIQMVKAMVALINNGKVIAPHLLLNEESGKTVVPYRPSGTPAQIADPASPYWGLVRQAMYGMANAPNGTGYKFFHTAPYGIAAKSGTSQVFSLKENQTYNAKMIPIRLRDHVFYTAFAPYKNPKVAIALILENGGSDGVTAAPIMRKILDHLFDPQADTTQPDQAP
What is the function of this protein?
Catalyzes cross-linking of the peptidoglycan cell wall.
What are the official names of this protein?
Peptidoglycan D,D-transpeptidase MrdA, Penicillin-binding protein 2, PBP-2.
What is the protein family that this protein belongs to?
Belongs to the transpeptidase family. MrdA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ACV1C_HUMAN
Sequence: MTRALCSALRQALLLLAAAAELSPGLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVIKSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHLPTASPNAPKLGPMELAIIITVPVCLLSIAAMLTVWACQGRQCSYRKKKRPNVEEPLSECNLVNAGKTLKDLIYDVTASGSGSGLPLLVQRTIARTIVLQEIVGKGRFGEVWHGRWCGEDVAVKIFSSRDERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVKEDCKA
What is the function of this protein?
Serine/threonine protein kinase which forms a receptor complex on ligand binding.  The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases.  Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3.  Receptor for activin AB, activin B and NODAL.  Plays a role in cell differentiation, growth arrest and apoptosis.
What are the official names of this protein?
Activin receptor type-1C, Activin receptor type IC, ACTR-IC, Activin receptor-like kinase 7, ALK-7.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein.
Protein: GLSA_BACC3
Sequence: MQCIETNNLQQLLEQVKPYTKKGKLATYIPELGNANPDDLGIAIFHKETEYIHAGNSQTLFTLQSISKVITLALALLDRGQEYVFSKVGMEPTGDPFNSIIKLETTSPSKPLNPMINAGALAITSMLAGKDNEEKMERILHFVREITDNPTINYSSKVANSELETAYLNRSLCYYMKQNGIIDCDIEELMDLYTRQCAVEVNCIDLARIGLIFAMDGYDPYKKKQIIPKHITKICKTFMVTCGMYNESGEFAIRVGIPAKSGVAGGIFGCVKGEMGIGIFGPALDANGNSIAGFKILELLSAQEGWSIF
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: UNG_LACJO
Sequence: MKKLIGNDWDEVLAPAFESEKYQELRDFLKEEYQTKQIFPDMYHIFTAFKLTSFADTKVVILGQDPYHNPGQATGMSFSVNPGVPLPPSLKNIYKELYDDVGAVPVNHGYLKKWADQGVLLLNAVLTVPYGNANGHRGKGWELITDTAIKALSDRGKVVFILWGKFAQNKIPLIDEGKNVIIKSPHPSPFSADRGFFGSRPFSRCNDALIKFGESPIDWQLPQEVNPADMA
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_STRP8
Sequence: MEEAKIPMLKLGPITFNLTLLAVCIVTIAVIFAFVFWASRQMKLKPEGKQTALEYLISFVDGIGEEHLDHNLQKSYSLLLFTIFLFVAVANNLGLFTKLETVNGYNLWTSPTANLAFDLALSLFITLMVHIEGVRRRGLVAHLKRLATPWPMTPMNLLEEFTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRVYWWPIAFLVNMAWTAFSVFISCIQAFVFTKLTATYLGKKVNESEE
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y3177_GLOVI
Sequence: MFTIELILRGNPVALAVQRKDQTAAGDLYAKIRDAMNASPPRVIELTCDKVPEKHLAVMSSDVVAVQLTAAKSGSGAPMGMRAGFFAGESEDE
What are the official names of this protein?
UPF0367 protein gsr3177.
What is the protein family that this protein belongs to?
Belongs to the UPF0367 family.
Protein: HPAHR_ACIBA
Sequence: MNQLNTAIVEKEVIDPMAFRRALGNFATGVTIMTAQTSSGERVGVTANSFNSVSLDPALVLWSIDKKSSSYRIFEEATHFGVNILSAAQIELSNRFARRSEDKFANIEFDLGVGNIPLFKNCSAAFECERYNIVEGGDHWIIIGRVVKFHDHGRSPLLYHQGAYSAVLPHPSLNMKSETAEGVFPGRLYDNMYYLLTQAVRAYQNDYQPKQLASGFRTSEARLLLVLESKTASSKCDLQREVAMPIREIEEATKILSEKGLLIDNGQHYELTEQGNACAHMLYKIAESHQEEVFAKYTVDERKLFKNMLKDLIGI
What is the function of this protein?
Reductase component of a two-component system that supplies reduced FMN (FMNH2) to the oxygenase component to catalyze the hydroxylation of 4-hydroxyphenylacetic acid, leading to the production of 3,4-dihydroxyphenylacetate (3,4-DHPA).  Catalyzes the reduction of free flavins (FMN, FAD and riboflavin) by NADH.  Subsequently, the reduced flavins diffuse to the oxygenase component C2.
What are the official names of this protein?
p-hydroxyphenylacetate 3-hydroxylase, reductase component, 4-HPA 3-monooxygenase small component, Flavin:NAD(+) oxidoreductase, p-hydroxyphenylacetate 3-hydroxylase C1 component.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family.
Protein: T6F_TERSU
Sequence: MATSGRLLCFCLVLGLVFESLGYSEARPPRDRKRTVTAKRYDPLAQRVDCGGSPCAFGCCENDVCRELDCEYAPPFGF
What are the official names of this protein?
Teretoxin Tsu6.15.
What is the protein family that this protein belongs to?
Belongs to the teretoxin M (TM) superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PUR5_GEOKA
Sequence: MAKAYKQAGVDIEAGYQAVALMKEHVQKTMRPEVLGGIGGFGGLFDLSALGYRQPVLISGTDGVGTKLKLAFLLDRHDTIGIDCVAMCVNDIIVQGAEPLFFLDYIACGKAVPEKIAAIVKGVADGCVEAGCALIGGETAEMPGMYDEDEYDLAGFAVGVAEKERLITGETIQAGDALVGLPSSGLHSNGYSLVRRIVFEQAKLSLDEIYEPLDVPLGEELLKPTRIYAKLLRSVRERFTIKGMAHITGGGLIENIPRMLPPGIGARIQLGSWPILPIFDFLREKGSLEEEEMFSVFNMGIGLVLAVSPETAAPLVEWLSERGEPAYIIGEVAKGAGVSFAGGGRA
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANM9_MOUSE
Sequence: MPNSRPRPRRGAGGGAGAAGRDRLVARSLQSAEHCLGDQDFGTAYAHYLLVLSLAPELKDDVKETFQYTLFKWAEELHALSRIQDLLGCYEQALELFPDDEVICNSMGEHLFRMGFRDEAAGYFHKAVKLNPDFNDAKENFYRVANWLVERWHFIMLNDTRRNMVYNAAIQKAVCLGSRTVLDIGTGTGILSMFAKKAGAQSVYACELSKTMYELACDVVAANKMENGIKLLHMKSLDIEIPKHIPERLSLVVTETVDAGVFGEGIVESLIHAWEHLLLQPKTKEENGNCGKYGKVIPAGAVIFGMAVECAEIRRHHRVGAKDIAGIHLPTNVKFQSPAYTSVDTEETVEPYTTEKMSGIPGGYLPLTECFQIMKVDFNNLQELKSLATKKPHSLNVPAIKEGVLDAIMVWFVLQLDDEYSLSTSPSEETCWEQAVYPVQALEDYCIQPGDRVTMEASCHDCYLRIQGISILHLEHEMEVMKGFTKSKDLLSLGNEAELCSALANLQTSRPEALEQTCMLEPTEIALLNNIPYHEGFKTAMRKVLSSLAPELLWQPMDTHCQYMEMNSGSGQSDAAPSTADPFYVLDVSEGFSLLPILAGTLGHVKPYSSVEKDQHCIALDLIAEANHFPKETLEFWLRHIEDEAAVLQRPKSDKLWSIIILDVIEPSGLIQQELMEKAAISRCLLQSGGKIFPQYVLMFGMLVESQTLVEESAVQGTEHTLGLNIAPFINQFQVPIRVCLDLSSLPCVPLSQPVELLRLDLMTPYLNTSNKEVKVRVCRSGRVTAVPFWFHLCLDDEVRLDTSGEASHWKQAAVVLDNPIQVQAGEELVLSVEHHKSNVSIAVKP
What is the function of this protein?
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).  Specifically mediates the symmetrical dimethylation of SF3B2.  Involved in the regulation of alternative splicing of pre-mRNA.
What are the official names of this protein?
Protein arginine N-methyltransferase 9, Protein arginine N-methyltransferase 10.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_ALKCK
Sequence: MAYAKLGRTSSQRKALLRDLVTDLIINERIETTEAKAKELRPIVEKMITLGKRGDLHARRQAAAFVRNEIADVESGQDAIQKLFADIAPRFAERQGGYTRILKVGPRRGDGAPMAIIEFV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: Y2934_MYCBO
Sequence: MCAVLDRSMLSVAEISDRLEIQQLLVDYSSAIDQRRFDDLDRVFTPDAYIDYRALGGIDGRYPKIKQWLSQVLGNFPVYAHMLGNFSVRVDGDTASSRVICFNPMVFAGDRQQVLFCGLWYDDDFVRTPDGWRIIRRVETKCFQKMM
What are the official names of this protein?
Uncharacterized protein Mb2934c.
Protein: TOIPB_XENLA
Sequence: MATSISTQRGQVFIGELPQDFLRISPTQQQQQIQLDAQAAQQLQYSGVMATMGRLSITVVQAKLAKNYGMTRMDPYCRIRLGYAVYETPTAHNGAKNPRWNKVIQCTIPPGVDSFYIEIFDERAFSMDDRIAWTHITIPETLKEGKHVDEWFSLSGKQGDDKEGMINLVMSYTSVPAMMPAQPVVLMPTVYQQGVGYVPIADPIYNPGMPMAAPPPAVNPQHETREEDIQSIKDMFPTMDPEVIRSVLEAQGGNRDAAVNSLLQMVEDS
What is the function of this protein?
Component of the signaling pathway of IL-1 and Toll-like receptors.  Inhibits cell activation by microbial products.  Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates.  The TOLLIP-dependent selective autophagy pathway plays an important role in clearance.
What are the official names of this protein?
Toll-interacting protein B.
What is the protein family that this protein belongs to?
Belongs to the tollip family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_BRADU
Sequence: MDAAVQVQRKKASNGAQVRNHWNVEEAKALYDLPFADLMLQAQRAHRKNFDPNHVETASLLSIKTGGCPEDCGYCSQSAHYATGLKATRLMRCADVVATAQRAKDAGATRFCMAAAWRTPKDRDLDSVCDMVNAVKGLGMETCVTLGTLTPKHAARLAEAGLDFYNHNVDTSPEFYSKIITTRSLQDRIDTLAHVRDAGIKICCGGIIGMGERVEDRLGMLVLLANLPNYPESVPINLWNKIEGVPVEDTAEPPDPIALVRLLATARVMMPRSVVRLSAGRQYMTDELQALCFLAGANSIFVGDVLLTTNNPKVDRDADLLARLGITSGLA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: HMOB_BACSU
Sequence: MKVYITYGTADFLKTIVQKHPSENILLMQGQENAILIHETNGDTVFQAPHAYEVIDQVGEIKHPGFAVLNNIAVTQEGRPLFENRFKNRAGKVENEPGFEAIRVLRPLDSDTYVILTLWETESAFQDWQQSGSYKEAHKKRDTSAGIDTTSIFSRPSYVTTYFAVE
What is the function of this protein?
Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.
What are the official names of this protein?
Heme-degrading monooxygenase HmoB, Heme oxygenase.
What is the protein family that this protein belongs to?
Belongs to the antibiotic biosynthesis monooxygenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLAV_SYNE7
Sequence: MAKIGLFYGTQTGVTQTIAESIQQEFGGESIVDLNDIANADASDLNAYDYLIIGCPTWNVGELQSDWEGIYDDLDSVNFQGKKVAYFGAGDQVGYSDNFQDAMGILEEKISSLGSQTVGYWPIEGYDFNESKAVRNNQFVGLAIDEDNQPDLTKNRIKTWVSQLKSEFGL
What is the function of this protein?
Low-potential electron donor to a number of redox enzymes.
What are the official names of this protein?
Flavodoxin.
What is the protein family that this protein belongs to?
Belongs to the flavodoxin family.
Protein: Y388_MYCLE
Sequence: MVEIGMGRVARRTYELREISIVPSRRTRSSKDVSTAWQLDAYRFEIPVVAHPTDALVSPEFAIELGRLGGLGVLNGEGLIGRHADVGAKVAQLIEAAEKEPEPATAVCLLQELHAAPLNPDLLGSAVARIREAGVTTAVRVSPQNAQVLTPVLLAAGIDLLVVQGSIVSAECVASGGEPLNLKTFISELDVPVVAGGVLDHRTALHLMRTGAAGVIVGYGSTRGATTSDEVLGISVPMATAIADAAAARREYLDETGGRYVHVLADGDIYTSGELAKAIACGADAVVLGTPLAQSAEALGGGWFWPAAAAHPSLPRGALLQTAVGERPSLQQVLNGPSDNPFGTLNLVGGLRRSMAKAGYCDLKEFQKVGLIVSI
What are the official names of this protein?
Uncharacterized oxidoreductase ML0388.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.
Protein: NTF2_CANAX
Sequence: MSVDFNAVATEFCNFYYNQFDSDRSQLGNLYRNESMLTFETSQLQGARDIVEKLASLPFQKVAHRISTLDAQPASANGDILVMVTGELLIDEEQNAQRYSQVFHLIPDNGSYYVFNDIFRLNYS
What is the function of this protein?
Facilitates protein transport into the nucleus.  Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import (By similarity).
What are the official names of this protein?
Nuclear transport factor 2, NTF-2.
What are the subcellular locations of this protein?
Cytoplasm.