PharMolix/UniProtQA huggingface dataset:
Protein: KAMD_FUSNN
Sequence: MGKLDLDWGLVKEARESAKKIAADAQVFIDAHSTVTVERTICRLLGIDGVDEFGVPLPNVIVDFIKDNGNISLGVAKYIGNAMIETKLQPQEIAEKVAKKELDITKMQWHDDFDIQLALKDITHSTVERIKANRKAREDYLEQFGGDKKGPYIYVIVATGNIYEDVTQAVAAARQGADVVAVIRTTGQSLLDFVPFGATTEGFGGTMATQENFRIMRKALDDVGVELGRYIRLCNYCSGLCMPEIAAMGALERLDMMLNDALYGILFRDINMKRTLVDQFFSRIINGFAGVIINTGEDNYLTTADAIEEAHTVLASQFINEQFALVAGLPEEQMGLGHAFEMEPGTENGFLLELAQAQMAREIFPKAPLKYMPPTKFMTGNIFKGHIQDALFNIVTITTGQKVHLLGMLTEAIHTPFMSDRALSIENARYIFNNLKDFGNDIEFKKGGIMNTRAQEVLKKAAELLKTIETMGIFKTIEKGVFGGVRRPIDGGKGLAGVFEKDNTYFNPFIPLMLGGDR
What is the function of this protein?
Catalyzes the migration of the L-beta-lysine and D-lysine epsilon amino group to the delta carbon to produce 3,5-diaminohexanoate and 2,5-diaminohexanoate, respectively.
What are the official names of this protein?
Lysine 5,6-aminomutase alpha subunit, 5,6-LAM, D-lysine 5,6-aminomutase alpha subunit, L-beta-lysine 5,6-aminomutase alpha subunit.
What is the protein family that this protein belongs to?
Belongs to the KamD family.
Protein: COPE_HUMAN
Sequence: MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAYLAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFLLMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDATLTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQEALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRLVLQYAPSA
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.  In mammals, the coatomer can only be recruited by membranes associated with ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).
What are the official names of this protein?
Coatomer subunit epsilon, Epsilon-coat protein, Epsilon-COP.
What is the protein family that this protein belongs to?
Belongs to the COPE family.
Protein: FGD4_HUMAN
Sequence: MEEIKPASASCVSKEKPSKVSDLISRFEGGSSLSNYSDLKKESAVNLNAPRTPGRHGLTTTPQQKLLSQHLPQRQGNDTDKTQGAQTCVANGVMAAQNQMECEEEKAATLSSDTSIQASEPLLDTHIVNGERDETATAPASPTTDSCDGNASDSSYRTPGIGPVLPLEERGAETETKVQERENGESPLELEQLDQHHEMKETNEQKLHKIANELLLTERAYVNRLDLLDQVFYCKLLEEANRGSFPAEMVNKIFSNISSINAFHSKFLLPELEKRMQEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAMELVKNMTERIPQFKSVVEEIQKQKICGSLTLQHHMLEPVQRIPRYEMLLKDYLRKLPPDSLDWNDAKKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEEDIVNPSNELIKEGQILKLAARNTSAQERYLFLFNNMLLYCVPKFSLVGSKFTVRTRVGIDGMKIVETQNEEYPHTFQVSGKERTLELQASSAQDKEEWIKALQETIDAFHQRHETFRNAIAKDNDIHSEVSTAELGKRAPRWIRDNEVTMCMKCKEPFNALTRRRHHCRACGYVVCWKCSDYKAQLEYDGGKLSKVCKDCYQIISGFTDSEEKKRKGILEIESAEVSGNSVVCSFLQYMEKSKPWQKAWCVIPKQDPLVLYMYGAPQDVRAQATIPLLGYVVDEMPRSADLPHSFKLTQSKSVHSFAADSEELKQKWLKVILLAVTGETPGGPNEHPATLDDHPEPKKKSEC
What is the function of this protein?
Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP.  Plays a role in regulating the actin cytoskeleton and cell shape.  Activates MAPK8 (By similarity).
What are the official names of this protein?
FYVE, RhoGEF and PH domain-containing protein 4, Actin filament-binding protein frabin, FGD1-related F-actin-binding protein, Zinc finger FYVE domain-containing protein 6.
Protein: TYPH_YERP3
Sequence: MFLAQEIIRKKRDGQPLSEEEIRFFINGIRDNVVSEGQIAALAMTIYFHDMSMPERVALTMAMRDSGTVLNWKSLNLNGPLVDKHSTGGVGDVTSLMLGPMVAACGGYVPMISGRGLGHTGGTLDKLEAIPGFDIFPDDNAFRKIIQNVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYSLSADLAQAIVGVANGAGCKTTALLTDMNQVLASSAGNGVEVREAVRFLTGEYRNPRLLEVTMALCVEMLLSGGLAHDEADARAKLQAVLDNGKAAEVFGRMVAAQKGPVDFVERYDSYLPVATLSKPVFAEQTGIITAMDTRALGMAVVALGGGRRRATDPIDYSVGLTEMARLGTRVDGQQPLAVIHANNEDDWQQAAEAVRAAITLGNNAPEETPVIYRRITE
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: HTPX_SHESA
Sequence: MKRIFLLIATNLAVLLVASIVMSILGVNTSTMGGLLVFAAIFGFGGAFISLAISKWMAKKTMGCEVITTPRDSTERWLLDTVARQAQQAGIKMPEVAIYQSPEMNAFATGPSKDNSLVAVSTGLLYGMSQDEVEGVLAHEVSHVANGDMVTLTLIQGVVNTFVIFAARVVAGIINNFVSSNDEEGEGLGMFAYMAVVFVLDMLFGILASIIVAYFSRIREYRADEGAARLAGKHKMIAALERLRQGPESSAMPAQMSAFGINGKRSMAELMMSHPPLEKRIAALQTR
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MINE_BORBR
Sequence: MSFLSFLLGQKKSSASVAKERLQIILAHERGRGDSPDYLPQLQQELVAVISKYVKIDPEDIKVHLERQDTLEVLEVKIEMPQN
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: RS15_SYNR3
Sequence: MPLNTEKKQELINSHQTHATDTGSVEVQVAMLSERITQLTGHLQSNKHDYSSRQGLMKMLGRRKSLLGYLKSQSSERYDTLIQKLGIRG
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: SC6A6_HUMAN
Sequence: MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLVIVIRLCQTEGPFLVRVKYLLTPREPNRWAVEREGATPYNSRTVMNGALVKPTHIIVETMM
What is the function of this protein?
Sodium-dependent taurine and beta-alanine transporter.  Chloride ions are necessary for optimal uptake.
What are the official names of this protein?
Sodium- and chloride-dependent taurine transporter, Solute carrier family 6 member 6.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.
Protein: RL27_RICAE
Sequence: MATKKAGGGSRNGRDSAGRRLGVKKTDGQYVIPGNIIVRQRGTKIHPGTNVGLGKDHTIFALIEGRVEFLTKRNHKIVNVKGIAST
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: LPXZ_BACTN
Sequence: MLKQKTLKDSFSLSGKGLHTGLDLTVTFNPAPDNHGYKIQRIDLEGQPTIDAVADNVTETTRGTVLSKNGVKVSTVEHGMAALYALGIDNCLIQVNGPEFPILDGSAQYYVQEIERVGTEEQSAVKDFYIIKSKIEFRDESTGSSIIVLPDENFSLNVLVSYDSTIIPNQFATLEDMHNFKDEVAASRTFVFVREIEPLLSAGLIKGGDLDNAIVIYERKMSQESYDKLADVMGVPHMDADQLGYINHKPLVWPNECARHKLLDVIGDLALIGKPIKGRIIATRPGHTINNKFARQMRKEIRLHEIQAPTYDCNREPVMDVNRIRELLPHRYPFQLVDKVIEMGASYIVGIKNITANEPFFQGHFPQEPVMPGVLQIEAMAQVGGLLVLNSVDEPERYSTYFMKIDGVKFRQKVVPGDTLLFRVELLAPIRRGISTMKGYAFVGEKVVCEAEFMAQIVKNK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
Bifunctional enzyme LpxC/FabZ.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the thioester dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HS189_ORYSJ
Sequence: MSMITSMLGRKQNAQQKGGGGGGRTGGGGGGEIEPVSVDIMEPFMDAISLTAFAAAPSAAAAAAGVPSTASMDWKETAAAHVFMADMPGVRREEVRVEVEEEKVLRISGQRARAAEEKGERWHRVERSSERFVRTVRLPPNANTDGVHAALDNGVLTITIPKDNDRKPHARIIPITN
What are the official names of this protein?
18.9 kDa heat shock protein, OsHsp18.9.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCAL1_BOVIN
Sequence: MEKACKEPEEQPQSPPKADEERPSVEPSPEKSSPEEQSSEEVSSEEEFFPDELLPELLPEMLESEERPPQERLSRKDLFEARPPMEQPPCGVGKHKLEEGSFKERLARSRPQFRGDIHGRNLSNEEMIKVAEEMEEMKRVRNKLMVMHWKARRNRPYPI
What is the function of this protein?
May be involved in transcriptional regulation.  Modulates various viral and cellular promoters in a promoter context-dependent manner.  Does not bind DNA directly (By similarity).
What are the official names of this protein?
Transcription elongation factor A protein-like 1, TCEA-like protein 1, Transcription elongation factor S-II protein-like 1.
What is the protein family that this protein belongs to?
Belongs to the TFS-II family. TFA subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: FRDD_KLEP3
Sequence: MINPNPKRSDEPVFWGLFGAGGMWGAIVAPVMVLLVGILLPLGLAPADAFSYERVLAFAQSFIGRAFIFLMIVLPLWCGLHRIHHAMHDLKIHVPNGKWVFYGLAAILSVITLVGVLFI
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Fumarate reductase 13 kDa hydrophobic protein, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RRP42_PYRHO
Sequence: MSDNEIVAGIMRDHIINLLKEGKRIDDRGFEDYRPIEIEVGIIEKAEGSALVKLGSTQVLVGIKTTLGEPFPDTPNMGVMTTNVELVPLASPTFEPGPPDERAIELARVTDRGIRESRALNLEKMVIVPGKIVRVVFIDVHVLDHDGNLMDAIGIASIAALLNAKVPKVEYNEETGEVEILEEKEPLPVERIPIPVTFAKIGNILVVDPSLEEELVMDGRLTVTTDETGHISAVQKGEGGAFKLEEVMYAVETAFKKAEEIRKIVLEAIKKSGE
What is the function of this protein?
Non-catalytic component of the exosome, which is a complex involved in RNA degradation.  Contributes to the structuring of the Rrp41 active site.
What are the official names of this protein?
Exosome complex component Rrp42.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family. Rrp42 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU1_SHESA
Sequence: MSNRVIIFDTTLRDGEQALAASLSVKEKLQIAMALERLGVDVMEVGFPVSSPGDFESVQTIARTIKNSRVCALSRALEKDIDAAAQALSVAEQFRIHTFISTSTIHVESKLKRSFEQVLEMAVGAVKYARRFTDDVEFSCEDAGRTPIDNLCRMVEAAIHAGARTINIPDTVGYTVPSEFGGIIQTLFNRVPNIDQAIISVHCHDDLGMSVANSITAVQHGARQIECTMNGIGERAGNCSLEEIAMILATRKNLLGVETGINAKEIHRTSNLVSQLCNMPIQSNKAIVGANAFTHSSGIHQDGMLKAQNTYEIMTPESIGLNRNNLNMTSRSGRHVIKHRMEEMGYSEQDFNLDALYEQFLHLADKKGQVFDYDLEALAFMEAQAAEDNFYQLQQLVVQSDSTEGVATATVRIDVGGEIKTEAATGNGPVDAAYNAIARATDRRIDIISYKLGAKGEGQNALGQVDITAVYHEQNFHGVGLATDVVEASARALVHVMNLTCRADKVADYKQNMHKNRELGGV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: PYRE_BACAC
Sequence: MKKEIASHLLEIGAVFLQPNDPFTWSSGMKSPIYCDNRLTLSYPKVRQTIAAGLEELIKEHFPTVEVIAGTATAGIAHAAWVSDRMDLPMCYVRSKAKGHGKGNQIEGKAEKGQKVVVVEDLISTGGSAITCVEALREAGCEVLGIVSIFTYELEAGKEKLEAANVASYSLSDYSALTEVAAEKGIIGQAETKKLQEWRKNPADEAWITA
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: FLOA_STAA2
Sequence: MFSLSFIVIAVIIIVALLILFSFVPIGLWISALAAGVHVGIGTLVGMRLRRVSPRKVIAPLIKAHKAGLALTTNQLESHYLAGGNVDRVVDANIAAQRADIDLPFERAAAIDLAGRDVLEAVQMSVNPKVIETPFIAGVAMNGIEVKAKARITVRANIARLVGGAGEETIIARVGEGIVSTIGSSKHHTEVLENPDNISKTVLSKGLDSGTAFEILSIDIADVDISKNIGADLQTEQALADKNIAQAKAEERRAMAVATEQEMKARVQEMHAKVVEAESEVPLAMAEALRSGNISVKDYYNLKNIEADTGMRNAINKRTDQSDDESPEH
What is the function of this protein?
Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts.  FMMs are highly dynamic and increase in number as cells age.  Flotillins are thought to be important factors in membrane fluidity.
What are the official names of this protein?
Flotillin-like protein FloA.
What is the protein family that this protein belongs to?
Belongs to the flotillin-like FloA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein.
Protein: FTE46_BOTJA
Sequence: MNSLVALVLLGQIIGSTLSSQVRGDLECDEKDAKEWTDTGVRYINEHKLHGYKYALNVIKNIVVVPWDGDWVAVFLKLNLLETECHVLDPTPVKNCTVRPQHNHAVEMDCDVKIMFNVDTFKEDVFAKCHSTPDSVENVRRNCPKCPILLPSNNPQVVDSVEYVLNKHNEKLSDHVYEVLEISRGQHKYEPEAYYVEFAIVEVNCTAQELHDDHHHCHPNTAGEDHIGFCRATVFRSHASLEKPKDEQFESDCVILHVKEGHAHSHLIQQHVEKDSISPEHNNTALNFVHPHNDTSTSHESHEHLAEVPVAFVKKELPKDISDRHTTPVKGCPGKVHHFEL
What is the function of this protein?
Potent inhibitor of hemorrhagic activity but also proteolytic activities of atrolysin C and jararhagin.  Inhibition occurs by formation of a non-covalent complex between BJ46a and the proteinases at their metalloproteinase domains.
What are the official names of this protein?
Antihemorrhagic factor BJ46a, Metalloproteinase inhibitor.
What is the protein family that this protein belongs to?
Belongs to the fetuin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CBF1_KLULA
Sequence: MSGKRSYQDDQLDVEEANKRHQMVDTLLRGSEDKDGDNDNSVYDDLLQDPEEVEKENKENRDGDKVGDDEHDVVKGESEGQAAEQSSADQNDENINVDVDPSVTAVARAAQHASQRREAGDEDEDEDEEEEEDEDDHVDIDDVDKDPDAVIDEDDDEEDEDQAQRRRGKKNIEGTGESNDSERATKIGESGSSNETAGADGSGDREDGSQPDGTEHDDEENGGAGAGGAAPRRGRKPGTETGSTAWKQQRKESHKEVERRRRQNINTAIEKLSDLLPVKETSKAAILSRAAEYIQKMKETETANIEKWTLQKLLGEQQVSSLTSANDKLEQELSKAYKNLEELKKKLKEAGIEDPTEEE
What is the function of this protein?
Required for chromosome stability and methionine prototrophy.  It is involved in chromosomal segregation.  Binds to a highly conserved DNA sequence (5'-RTCACRTG-3'), called CDEI, found in centromeres and in several promoters (By similarity).
What are the official names of this protein?
Centromere-binding protein 1, CBP-1, Centromere promoter factor 1, Centromere-binding factor 1.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere.
Protein: THYN1_DANRE
Sequence: MPPRKTRSSAKSNKHSDADAHLNEGSDDVAQRKTGKRKRSAAVKGDVENKNDDDACKPSYSRWLMKSEPESRIENGVDVKFGIEDLKALPNQTGCWDGVRNYQARNFMREMKVGQQAFFYHSNCKEPGIAGLMKIVKEAYVDHTQFDKKDVHYDPSSKADNPKWHMVDVQFERMVKRFIPLAELKKYHLEHRVKGGPLKDMALFTRARLSVQPLTAEEFEFVLSLENEDPI
What is the function of this protein?
Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.
What are the official names of this protein?
Thymocyte nuclear protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: EMRB_ECO57
Sequence: MQQQKPLEGAQLVIMTIALSLATFMQVLDSTIANVAIPTIAGNLGSSLSQGTWVITSFGVANAISIPLTGWLAKRVGEVKLFLWSTIAFAIASWACGVSSSLNMLIFFRVIQGIVAGPLIPLSQSLLLNNYPPAKRSIALALWSMTVIVAPICGPILGGYISDNYHWGWIFFINVPIGVAVVLMTLQTLRGRETRTERRRIDAVGLALLVIGIGSLQIMLDRGKELDWFSSQEIIILTVVAVVAICFLIVWELTDDNPIVDLSLFKSRNFTIGCLCISLAYMLYFGAIVLLPQLLQEVYGYTATWAGLASAPVGIIPVILSPIIGRFAHKLDMRRLVTFSFIMYAVCFYWRAYTFEPGMDFGASAWPQFIQGFAVACFFMPLTTITLSGLPPERLAAASSLSNFTRTLAGSIGTSITTTMWTNRESMHHAQLTESVNPFNPNAQAMYSQLEGLGMTQQQASGWIAQQITNQGLIISANEIFWMSAGIFLVLLGLVWFAKPPFGAGGGGGGAH
What is the function of this protein?
Part of the tripartite efflux system EmrAB-TolC, which confers resistance to antibiotics.
What are the official names of this protein?
Multidrug export protein EmrB.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. EmrB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YHAK_ECO57
Sequence: MITTRTARQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLNQEVLAPGAAFQPRTYPKVDILNVILDGEAEYRDSEGNHVQASAGEALLLSTQPGVSYSEHNLSKDKPLTRMQLWLDACPQRENPLIQKLALNMGKQHLIASPEGAMGSLQLRQQVWLHHIVLDKGESANFQLHGPRTYLQSIHGKFHALTHHEEKAALTCGDGAFIRDEANITLVADSPLRALLIDLPV
What is the function of this protein?
Does not have quercetin 2,3-dioxygenase activity.
What are the official names of this protein?
Pirin-like protein YhaK.
What is the protein family that this protein belongs to?
Belongs to the pirin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADHE_BILW3
Sequence: MDVRQQDVERIVVEVLKKMMSDQPTAAATTVVAASGCDCGDFGLFDRLEDAVQAAEAAQKKISTVAMRDKIIAAIRKAGLENAKAFAEIAHNETGMGRVSDKIAKNILVCERTPGTECLSPMAISGDMGLTLIENAPWGVIASVTPSTNPTATVINNAISMIAGGNSVIFAPHPNAKRASQTAIQVLNKAIIEATGVANLLVAVKEPTIEVAQELFSHPRIKLLVVTGGEAVVAQARKVATMRLIAAGAGNPPVVVDETANIARAARSIYDGASFDNNIICADEKEIIAVDSIADQLKAEMKAIGAVEISLEQADAVARVVLRNYPQVEGGKAPNPNPKWVGRDAALIAKAAGIDVPDSCRLLIVDVKRDINHVFARVEQLMPVIPLLRAANVDEAIEWALILERGLSHTAGMHSRNIDNMDKMARAMNTSLFVKNGPHLAALGAGGEGWTTMTISTPTGEGVTCARSFVRLRRCCVVDNFRIV
What is the function of this protein?
Involved in an anaerobic respiration pathway that converts the sulfonate taurine (2-aminoethanesulfonate) to ammonia, acetate and sulfide.  Catalyzes the oxidation of acetaldehyde to acetyl-CoA in the presence of CoASH and NAD(+).  Highly prefers NAD(+) over NADP(+).
What are the official names of this protein?
Acetaldehyde dehydrogenase (acetylating), CoA-acylating acetaldehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: SYI1_BURMA
Sequence: MSNKKADSKPQAKYPVNLLDTPFPMRGDLPKREPQWVEDWEARGVYEKIRAASQGRPKFILHDGPPYANGDIHLGHAVNKILKDMVVKSRNMAGFDAPYVPGWDCHGMPIEIQIEKRFGKSLPAAEVMAKARAYATEQIEKQKVGFKRLGVLGEWGNPYKTMNFQNEAEEIRALGKIIEKGYVYRGLKPVNWCFDCGSALAEAEVEYKDRTDPTIDVLFAFAEPEKTAHAFGLAELPRAEGGIVIWTTTPWTIPANQALNLHPEIVYALVDTERGLLVMAEERVEACMKDFGLTGRVIARTPGEKLANLRFHHPLAAAHPGYKRTSPVYLGDYVTTDTGTGVVHSSPAYGVEDFTSCKAHGMTDSDIINPVMGDGRYIESLPLFGGLTIWDANPKIVDALKAAGSLLRNERYAHSYMHCWRHKTPIIYRATSQWFAGMDTQPAGGGKTLRETALDAVDATAFYPSWGKQRLHAMIANRPDWTLSRQRQWGVPMAFFVHKETGELHPRTLELLEEVAKRVERQGIEAWQTLDARELIGDDANLYEKNRDTLDVWFDSGTTHWHVLRGSHKDQLQFPADLYLEGSDQHRGWFHSSLLTASMLDGRAPYKGLLTHGFTVDGEGRKMSKSLGNGIDPHEVANRLGAEIIRLWIASTDYSGELAISEEILKRVTEGYRRIRNTLRFLLANLSDFDYAKDALPAGQWLEIDRYAVAFAAQLQAELLAHYEKYEFHPVVAKLQTFCSEDLGGFYLDVLKDRLYTSAPASPARRSAQTALYHVTQGLLRVLAPFLSFTAEEAWRVFQPQSDTIFTETYYAYPEIAGAEALIAKWTLLRDVRGDVTKALEEARTANRIGSSLQAQVEVRASGARYDALASLGDDLKFVLITSAATVVKVDAQGDESVDVAASTYPKCERCWHYREDVGAHADHPTLCGRCFSNLFENGETRSAA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase 1, Isoleucyl-tRNA synthetase 1, IleRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBID_ECOLC
Sequence: MKYNDLRDFLTLLEQQGELKRITLPVDPHLEITEIADRTLRAGGPALLFENPKGYSMPVLCNLFGTPKRVAMGMGQEDVSALREVGKLLAFLKEPEPPKGFRDLFDKLPQFKQVLNMPTKRLRGAPCQQKIVSGDDVDLNRIPIMTCWPEDAAPLITWGLTVTRGPHKERQNLGIYRQQLIGKNKLIMRWLSHRGGALDYQEWCAAHPGERFPVSVALGADPATILGAVTPVPDTLSEYAFAGLLRGTKTEVVKCISNDLEVPASAEIVLEGYIEQGETAPEGPYGDHTGYYNEVDSFPVFTVTHITQREDAIYHSTYTGRPPDEPAVLGVALNEVFVPILQKQFPEIVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGVWSFLRQFMYTKFVIVCDDDVNARDWNDVIWAITTRMDPARDTVLVENTPIDYLDFASPVSGLGSKMGLDATNKWPGETQREWGRPIKKDPDVVAHIDAIWDELAIFNNGKSA
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MTM2_METJA
Sequence: MNLDAWLDIQPAKKLYTIKEASRILTKKFGKEIKEHNISYLVQYGRVNKYKIKNRVYVDIDEVENYYKKLFFEKRKEWEEKLGFKLDWDLAFDLLSEKERTKHVHGIHPYKGKFIPQLVEYFLKRHFNVGDIIIDPFMGSGTTLVQCMEMGINSIGIDISPFNCLIAEVKLQKYDIQKLKKILLDMLNKTKEFSKNLGDDEFVKEMDKLIEKYNKKYFTLEYKRKLSKKEIDEDSYSEKIMEMFYLEYKKLKEKYCKNDDEFDDIFKDKPFLYKWYSPRIRAELNFYLNLIKDCRDETIKKVAMIILSRTARSVRGTTHFDLATLKEPVFDPYYCYKHKKICRPVQTILRHLEEYTNDVISRIEEFSKIRKDAYYLIINGDSRTVDIEEELKKHPNFYELYKNKKIDGIFTSPPYLGQIDYHEQHAYAYELFDIPRLDELEIGPKFKGSSKKAQKEYIEGISDVLINMKRFLNEDAKIFIVVNDKKNLYKEIFEKSGLILVREFKRPVLNRTERDRNPYYESIFELKMEE
What is the function of this protein?
An alpha subtype methylase that recognizes the double-stranded sequence 5'-GGNCC-3', methylates C-5 on both strands, and protects the DNA from cleavage by the MjaII endonuclease.
What are the official names of this protein?
Type II methyltransferase M.MjaII, M.MjaII, N-4 cytosine-specific methyltransferase MjaII.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.