PharMolix/UniProtQA huggingface dataset:
Protein: CAZA2_COLGU
Sequence: MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCEVENAVESWRTSVETALRAYVKEHYPNGVCTVYGKKIDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTITPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA
What is the function of this protein?
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends.  Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
What are the official names of this protein?
F-actin-capping protein subunit alpha-2, CapZ alpha-2.
What is the protein family that this protein belongs to?
Belongs to the F-actin-capping protein alpha subunit family.
Protein: CH60_MYCVA
Sequence: PYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLRNVAAGANPLGLKRGIEKAVEAVTQSLLKSAKEVETKEQISATAAISAGDTQIGELIAEAMDKVGNEGVITVEESNTFGL
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, 65 kDa heat shock protein, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRC2_CAEEL
Sequence: MGSCIGKEDPPPGATSPVHTSSTLGRESLPSHPRIPSIGPIAASSSGNTIDKNQNISQSANFVALFQYDARTDDDLSFKKDDILEILNDTQGDWWFARHKATGRTGYIPSNYVAREKSIESQPWYFGKMRRIDAEKCLLHTLNEHGAFLVRDSESRQHDLSLSVRENDSVKHYRIRQLDHGGYFIARRRPFATLHDLIAHYQREADGLCVNLGAPCAKSEAPQTTTFTYDDQWEVDRRSVRLIRQIGAGQFGEVWEGRWNVNVPVAVKKLKAGTADPTDFLAEAQIMKKLRHPKLLSLYAVCTRDEPILIVTELMQENLLTFLQRRGRQCQMPQLVEISAQVAAGMAYLEEMNFIHRDLAARNILINNSLSVKIADFGLARILMKENEYEARTGARFPIKWTAPEAANYNRFTTKSDVWSFGILLTEIVTFGRLPYPGMTNAEVLQQVDAGYRMPCPAGCPVTLYDIMQQCWRSDPDKRPTFETLQWKLEDLFNLDSSEYKEASINF
What is the function of this protein?
Non-receptor tyrosine-protein kinase which may play a role in larval and pharynx development.  Unlike src-1, does not play a role in embryonic development.
What are the official names of this protein?
Tyrosine protein-kinase src-2, SRC oncogene related protein 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
Protein: RL34_BACAN
Sequence: MKRTYQPNKRKRSKVHGFRSRMSTANGRKVLAARRRKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: YKYL_CAEEL
Sequence: MHTGCCTTKFDTEVLIIGNGPAGIALSSFLSGMHPFYDATHPHENVTVHEKLLANHDFSLIDQDLSWSSNLTELSQSGRPLSVLYDMLVRPGADMGSDAPGCIQWELNRRREIPHMVIGETKIGGSWNEYDAEMLTVSFSDWMDMPGFTMEQWLGGRPLVKRLPSVAIATYLKKYVERLRLRKKFHQYFVVNSIKKIGDVWVTSGKRSTDGRSFVIRSKQVVVACGKTSPRKLQLPNEEHCSSNIVYDVRALKERLDATKKTVIDEDENYDTPSTSTCSPVIVVGDGVSSVDCVRHCLERDIPVVHVIRRTLRELRNVMLSRLSPIHYSEYTDIYRMMIGRSVHKNYQRVLDASITSVSKIHVEITTGSNREIIEMPYSTVAVCIGRESHFSTVFENAHTFLDYQSEQDETLFAVGAYAGDHFVRFLVGGCLRVAQHITGAANNNNVTAKLLPIC
What are the official names of this protein?
Uncharacterized protein F30B5.4.
What is the protein family that this protein belongs to?
Belongs to the OKL38 family.
Protein: SUB2_DEIRA
Sequence: MPGALPMKKISLAVLSLTTLLAACGQPQTSPQSPAASAPSVAVPRTHALDIDPAQVVTTKNGDMYVRNQLVVNLRGHSADALADQLGGRVLDQLPELDVALIELPQGKDARSVGVALMREGQVLYAAAQTVQRQIEPVRTAQDQLGAQAVNQVFDTLPQYALDSNHLHAKAAWDAGFTGKGVKVGVIDDPSDVSHPDLRPNWAGKAYDPATNTTYTTVQGWIDAIDGFDGKVDNKVDPGIEHGTAVASTIAAAKNGQGIVGVAPDSKFYTAAIFQPGFIGDYLVARSVIWTVNQGAQVINNSWGGTGYSPLLKQAFDYALERDITVVVSAGNSYREEWRNPAQLPGVIASAALDINNDKAGFSTYGRHVSVAAPGVDVMLASPLFINADGTRKTGGYTKDGGSGYQLISGTSFSGPYTSGVAAVILGAKPDLDPHQVRRLMEETADGSVGSNKAGFDRETGYGLIRMDKLADRLKGSNMPQKGGAGRVKVEIQTPGGYVPGILADVILEGDGADGAVYAVQTDSDGYANFVSIAPGTYTLRVATPDLTLTGGQSDERDTYVGKLTVTSGSVLSTVAPQRVVLVKGAVDLNPVDPYEPNDTMAEAKPISYGKMTELAYIFGKPRDVDFFSFTGKAGDNIQADVHARTAIGGSLDSFLVLRDASGKNLAYNDDANGQDSVITFKLPADGTYFLEVSSCNILCKSNGDDASKGQDDDSPFNKYVLELQLLK
What are the official names of this protein?
Probable subtilase-type serine protease DR_A0283.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: YCS3_SCHPO
Sequence: MKFSTVGFLFSTILFKSAFAGWMDTHMKDEHHIDKYTDESFFRLHDLGKKGYWSDQDILSLYGLFENDEVPFVKKNEVLVDVLKKCDPSGNRRITLDEFLAFRKNGGELTDFGFPGHHGDEEEEFEMHHVEKYHPAGLDEPDENWNHPEDIEHFQKHDEIFHGDKKPEERRKHFVKYNNIPDKYRRVSI
What are the official names of this protein?
Uncharacterized calcium-binding protein C613.03.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Golgi apparatus lumen.
Protein: AGUA_SHEB2
Sequence: MTNANVDATPLTTKPSQDGFYMPAEWAAQQAVWMIWPYRPDNWRSAGAYAQATFAKVADAIGAATPVYMGVPKAFLAEAKTVMPSHVTLVEMDSNDCWARDTGPTVVVNDNGECRGVDWGFNAWGGHNGGLYFPWDKDEQVAQQMLKQHGFARYSAPLILEGGSIHVDGEGTCMTSAECLLNANRNPDLTKEQIEDLLRDYLNVKQFIWLQDGVYMDETDGHIDNMCCFARPGEVILHWTDDETDPQYSRSKAAFDVLQNTVDAQGRKLKIHLLPQPGPLYCTEEESKGVTEGTGVPRTAGERLAGSYVNFLITNNRIVFPLLDPATDDIAAQKLQEIFPEYEIVGVPAREILLGGGNIHCITQQIPSGK
What are the official names of this protein?
Putative agmatine deiminase, Agmatine iminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the agmatine deiminase family.
Protein: GLYA_CLOAB
Sequence: MDFENIKVSDSEVYSIIEEENARQENNIELIASENFTSKAVMEAMGSYLTNKYAEGYPGKRYYGGCYVVDKVEELARERAKKLFKAEHANVQPHSGSQANMAVYFAVLKPGDTIMGMNLTDGGHLTHGSPVNFSGKLFNIIAYGVSDETEQIDYEAFRKKALECKPKMIVSGASAYSRIIDFKKIREICDEVGAYMMVDMAHIAGLVAAGLHPSPIPYADFVTTTTHKTLRGPRGGAIFCKEKYAKDIDKSVFPGMQGGPLMHIIAGKAVCFGEALKDDFKDYAQQIVNNAKVFADELTKYGFRIVSGGTDNHLLLVDLTNKNITGKDAEHLLDSVGITANKNTIPFEKKSPFITSGIRMGTPSVTTRGFKEEEMKKVAYFINYVIEHRDEDLSEIRKQVSELCSGFPIYK
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_DESAP
Sequence: MLIRKAEVRRQTRETEIRVQLQVDGTGEYALDTGVPFLEHMLALTAKFSGFDLQIRARGDLDVDDHHTVEDVGICLGEALVKALGDKAGIGRFGHAIVPMDDALALVAVDLSGRGYLAFDVPMPSPQVGRFDTELVEEFLRALAYNGRFNLHVRLLAGANTHHIIEAVFKGLGVALGSAARINAQRGVPSTKGVIN
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD1_BRAHW
Sequence: MKESDKLQILKPTASAIFDIARELGMIKEIYNELSECSKLFQDIDIKKYFFDKSISKKDKKELIDKRLKPILSKETYAFVSILTEHDSIDVLPDIVALYKEIADDYSNIVRVRIITASTIDDKTVEDIIQTVKCFSSNEISYETIVDENIIGGIIVYIGSVVYDYSIKKQIDLLQSKFTYGN
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta 1, ATP synthase F(1) sector subunit delta 1, F-type ATPase subunit delta 1, F-ATPase subunit delta 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: 3NBB_BOIIR
Sequence: MKTLLLAVAVVAFVCLGSADQLGLGRQQIDWGKGQAKGPPYTLCFECNRETCSNCFKDNRCPPYHRTCYTLYRPDGNGEMKWAVKGCAKTCPTAQPGESVQCCNTPKCNDY
What is the function of this protein?
This bird and reptile-specific postsynaptic neurotoxin inhibits the chick muscle alpha-1-beta-1-gamma-delta (CHRNA1-CHRNB1-CHRNG-CHRND) nicotinic acetylcholine receptor (nAChR) 100-fold more compared with the mouse receptor.  In vivo, produces rapid flaccid paralysis, dyspnea and increased respiratory rate in geckos.  At sublethal doses geckos were immobilized for up to three days and then recovered.  Chicks injected with lethal doses showed rapid onset of inactivity, dyspnea and neck droop, and no extended paralysis with survival was seen.
What are the official names of this protein?
Irditoxin subunit B, IrTxB.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Ancestral subfamily. Boigatoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL11_CHLSY
Sequence: MAKKLVAVVKLQLPAGKATPAPPVGPALGQYGINIMAFVKEYNEKSASQAGSIVPVEISVYSDRSFVARLLTPPAADLLRKAAGIQKGASTPKRTTVGTITRAQLRQIAQQKLPDMNANDIEAAERIIAGTARSMGIKIVE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: KYNU_SCHJA
Sequence: MKILQYKSIENVQYSKNILYFCGHSMGLQPKSTKIYINKILNQWKNLGVLSYHYGELPASYCDEQLSIDCAQWIVNAKFNEVSITCNLTVNMHVLIAKFYRPTNEKYCILIENDIFPSDYYVLESHIQWHGYNTNDCFIKLKPRLHEYCLRNDDILPEIIKNQHRIALIWLPGIQYITGQLFNMKLITEWGHQYAKCPVGWDLAHAVGNIPLYLHDWNIDMAVWCSYKYLNGSPGAIGGLFIHEKHHHEEGSYGPKFIEFTNNNNITIFNNINGPQLTGWWSHRSETRFNMTGNMELAKGANAYRLSNPPLLLAAALTVSVNIIKSCGGMINLREKSIKLTDYLEYLITNSSLALKHDHYCLVTPSNSNERGAQLTISVTHMNIQVVYENLLKLGVICDYRLPNFLRITPIPLYNSFEDVYLLAKCLHQVLNDTLN
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase, L-kynurenine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_HELPJ
Sequence: MRALETIATLREYRKSLKESVGFVPTMGALHRGHQSLIERSLKENSHTIVSVFVNPTQFGANEDFSAYPRPLEKDLALCEKSGVNAVFAPKIGEMYPYEAKQRLKLYAPAFLSHSLEGAVRKGHFDGVVQVVLRLFHLTNPTRAYFGKKDAQQLLIIQHLVQDLLLDIEIAPCEIVRDSDNLALSSRNVCLNATERKQALAIPKALEKIQQAIDRGEKACEKLKKLGLEILKNLEVDYLECCNHKLEPLKTIEPANTLVLVAARVGKTRLLDNLWV
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHSS2_MOUSE
Sequence: MRASLLLSVLRPAGPVAVGISLGFTLSLLSVTWVEEPCGPGPPQPGDSELPPRGNTNAARRPNSVQPGSERERPGAGAGTGESWEPRVLPYHPAQPGQATKKAVRTRYISTELGIRQKLLVAVLTSQATLPTLGVAVNRTLGHRLEHVVFLTGARGRRTPSGMAVVALGEERPIGHLHLALRHLLEQHGDDFDWFFLVPDATYTEAHGLDRLAGHLSLASATHLYLGRPQDFIGGDTTPGRYCHGGFGVLLSRTLLQQLRPHLESCRNDIVSARPDEWLGRCILDATGVGCTGDHEGMHYNYLELSPGEPVQEGDPRFRSALTAHPVRDPVHMYQLHKAFARAELDRTYQEIQELQWEIQNTSRLAADGERASAWPVGIPAPSRPASRFEVLRWDYFTEQYAFSCADGSPRCPLRGADQADVADVLGTALEELNRRYQPALQLQKQQLVNGYRRFDPARGMEYTLDLQLEALTPQGGRWPLTRRVQLLRPLSRVEILPVPYVTEASRLTVLLPLAAAERDLASGFLEAFATAALEPGDAAALTLLLLYEPRQAQRAAHSDVFAPVKAHVAELERRFPGARVPWLSVQTAAPSPLRLMDLLSKKHPLDTLFLLAGPDTVLTPDFLNRCRMHAISGWQAFFPMHFQAFHPAVAPPQGPGPPELGRDTGHFDRQAASEACFYNSDYVAARGRLVAASEQEEELLESLDVYELFLRFSNLHVLRAVEPALLQRYRAQPCSARLSEDLYHRCRQSVLEGLGSRTQLAMLLFEQEQGNST
What is the function of this protein?
May facilitate PRKN transport into the mitochondria.  In collaboration with PRKN, may enhance cell viability and protect cells from oxidative stress.
What are the official names of this protein?
Chondroitin sulfate synthase 2, Chondroitin glucuronyltransferase 2, Chondroitin-polymerizing factor, ChPF, Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II, N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II, N-acetylgalactosaminyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
What are the subcellular locations of this protein?
[Isoform 1]: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Cytoplasm, cytosol. SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm, cytosol. Mitochondrion. SUBCELLULAR LOCATION: [Isoform 2]: Mitochondrion matrix.
Protein: RL22_TREPA
Sequence: MTERVTYRAKTKFLVASPTKVRPVANVVKCKPYVRAMALLGHLPHKGARLISKVMKSAASNAIDRDKRLDEERLFVRDIQIDEGPRLKRLWCRGRGRGDVQLKRMCHITVVVEESVRTKDGSKG
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: SPTC3_HUMAN
Sequence: MANPGGGAVCNGKLHNHKKQSNGSQSRNCTKNGIVKEAQQNGKPHFYDKLIVESFEEAPLHVMVFTYMGYGIGTLFGYLRDFLRNWGIEKCNAAVERKEQKDFVPLYQDFENFYTRNLYMRIRDNWNRPICSAPGPLFDLMERVSDDYNWTFRFTGRVIKDVINMGSYNFLGLAAKYDESMRTIKDVLEVYGTGVASTRHEMGTLDKHKELEDLVAKFLNVEAAMVFGMGFATNSMNIPALVGKGCLILSDELNHTSLVLGARLSGATIRIFKHNNTQSLEKLLRDAVIYGQPRTRRAWKKILILVEGVYSMEGSIVHLPQIIALKKKYKAYLYIDEAHSIGAVGPTGRGVTEFFGLDPHEVDVLMGTFTKSFGASGGYIAGRKDLVDYLRVHSHSAVYASSMSPPIAEQIIRSLKLIMGLDGTTQGLQRVQQLAKNTRYFRQRLQEMGFIIYGNENASVVPLLLYMPGKVAAFARHMLEKKIGVVVVGFPATPLAEARARFCVSAAHTREMLDTVLEALDEMGDLLQLKYSRHKKSARPELYDETSFELED
What is the function of this protein?
Serine palmitoyltransferase (SPT).  The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core.  The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference.  SPT complexes containing SPTLC3 generate shorter chain sphingoid bases compared to complexes containing SPTLC2.  The SPTLC1-SPTLC3-SPTSSA isozyme uses C12-CoA, C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA.  On the other hand, the SPTLC1-SPTLC3-SPTSSB has the ability to use a broader range of acyl-CoAs without apparent preference.
What are the official names of this protein?
Serine palmitoyltransferase 3, Long chain base biosynthesis protein 2b, LCB2b, Long chain base biosynthesis protein 3, LCB 3, Serine-palmitoyl-CoA transferase 3, SPT 3.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: MON2_XENLA
Sequence: MSSTSTTSSPEAIKKLLDNMQSDLRGLSMECKKKFPPVKEAAESGIVKVKNIAARSPDVLTALKENSSEVVQPFLMGCGTKEQKITQLCLAAIQRLMSHEVVSEGAAGNIINMLWQLMENGLEELKLLQTVLVLLTTNTVVHDESLSKAIVLCFRLHFTKDNITNNTAAATVRQVVTVVFERMVTEDERHKDAVEQPIPVTGNSNRRSVSTLKPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSNSNSSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDADKPQWLRAVAVESIHRLCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLIPSAGPASATTNPPGGSSSITPASNPTTSGMATATSNTTVLPAFEYRGTWIPILTISIQGSAKATYLEMLDKVEPPTIPEGYALSVAFHCLLDLVRGITTMIEGEIGQAETDSHISAEETPSHAPTINPQELPAVSDPADKGCRSVWEEMINACWCGLLAALSLLLDASTDETATENILKAEMTMASLCGKLGLVTPRDAFITAICKGSLPPHYALTVLNTSSAAICNKSYSIQGQNVQMISPSSDSHQQVVAVGQPLAVQPQGTVMLTAKNIQCMRTLLNLAHCHGGFLGTSWQLVLATLQHLVWILGLKPSSGGALKPGRAVEGPSTVLTTAVMTDLPIISNILSRLFESSQYLDDVSLHHLINALCSLSLEAMDMAYGNNKEPSLFAVAKLLETGLVNMHRIEILWRPLTGHLIEVCQHPNARMREWGAEALTSLIKAGLDFKHEPQLSENQRLQLLLLNPLKELSNIIHHDIRLKQLECVLQILQSQGDSLGPGWPLVLGVIGAIRNDQGESLIRNAFQCLQLVVTDFLPTMPSTCLQIVVEVAGSFGLQNQELNISLTSIGLLWNISDYFYQRGETIEKELNLEEDLLQKQAKEKGIILNRPFHPAPPFDCLWLCLYAKLGELCVDIRPAVRKSAGQTLFSTIGAHGTLLQHATWHTVIWKVLFQLLNQVRESSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQPLGEFTKAWDVLLDHIQSAALSKSNEVSLAALKSFQEILQIVSPTRDNDKPESLPGISAPVPVLIGPVNASGPGRPLVRSDSTGERLSRYSIPEQPIAVDEIEDSALWWAAWNTWYRIGTESTKPPISCDKLTFIPSQPFLTALIQIFPALYQHIKTAFSMDDLQKLGVILHGAVSVPISSDASPFILPSYTEAVLTSLQESVLTALDVLQKEICVGPENMQIMYPAIFDELSAFVQFSCKPPQYGKLETKHIANAKYNQIQLFAPAEWVALNYVPFAEKSLEVMVDLYQKTACHKAVVNEKVLQNVIKTLRVPLSLKYACPSESTWKLAVSSLLKVLSVGLPVARQHVSSGKFDSMWPELASTFEDFLFTKSTPPDNLSIEEFQRNEGIDVEVVQLISMEILPYANFIPKDFVGKIMTMLNKGSIHSQSSSFTEAEIDIRMREEFSKVCFETLLQFSFSNKVTTPQEGYISRMALSVLLKRSQDVLHRYIEDEKLSGKCPLPRQRVTEIIFVLKAVSTLIDSLKKTHPENVDANTWAQVISLYPTLVECITCSSSEVCTALKEALVPFKDFMHPPAAAKVQNGES
What is the function of this protein?
May be required for traffic between late Golgi and early endosomes.
What are the official names of this protein?
Protein MON2 homolog.
What is the protein family that this protein belongs to?
Belongs to the MON2 family.
Protein: YBC7_SCHPO
Sequence: MFSLLRKAIDVNRSRITLHGIKVHSINTFRLIPYSLSLTKQIRFYASEGTDAGEMEKGLSVVNANHENRPFRDLEGYHFNTFTFLKTLMDKGYTEKEAEGLLEVTNMFVTDMLRHSHLNYLSEADFENCSYLFRTALSELRSEKINMRKDQISSLRSGLFSNQREVESLEQLVHEQLNKLNTESKMEFENRKNDTKNEVQQLSARIVELHNLLAVSLGKLRAENERQKWDQIRKAAGVVMAFTGFLVLVIPFGLGVRSRKKEKQDELDNLGSFNLDNKRDDYTDTNLSHM
What are the official names of this protein?
Uncharacterized protein C27B12.07.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: DER22_ARATH
Sequence: MAQAVEEWYKQMPIITRSYLTAAVITTVGCSLDIISPYNLYLNPTLVVKQYQYWRLVTNFLYFRKMDLDFMFHMFFLARYCKLLEENSFRGKTADFLYMLLFGASVLTGIVLIGGMIPYLSASFAKIIFLSNSLTFMMVYVWSKQNPYIHMSFLGLFTFTAAYLPWVLLGFSILVGASAWVDLLGMIAGHAYYFLAEVYPRMTNRRPLKTPSFLKALFADEPVVVARPEDVRFAAAPFDEIHQD
What is the function of this protein?
May be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins.
What are the official names of this protein?
Derlin-2.2, AtDerlin2-2.
What is the protein family that this protein belongs to?
Belongs to the derlin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: FSIP1_DANRE
Sequence: MEVYSGQMGENPHSRGLEMDAEGSRDKSISSPREIGDQVSVDCMDIIKGRLDEISRPASSSSLSENRRKSAEGHRSLEVLSPDLNHTLFQRSIHEMTDQTTETSSDHEDSEEENEDPEMRKAIRKMKKLDRILAHKVSAEREVKQKGRELHQRLWQELQAESLHISSTEAENTRRFLSLTPSDCLECDEEDVFVPVFETEVVDLKTEVNSRPEPEECVEAAGHAEVGQEVTEDRRHTGASHSKSRHDFVKKNIELAGASGSSVFLTQQEKERIEDLLKDLEEELLEEPQLVLSSLSAGQGFSPEPSERHTLFNIDSRLQLLLPMQDFLSVRSSSSQGSLEESTGDQGLWTMRQRRDEERRLREIQEQLQILEET
What are the official names of this protein?
Fibrous sheath-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the FSIP1 family.
Protein: BMRF2_EBVB9
Sequence: MFSCKQHLSLGACVFCLGLLASTPFIWCFVFANLLSLEIFSPWQTHVYRLGFPTACLMAVLWTLVPAKHAVRAVTPAIMLNIASALIFFSLRVYSTSTWVSAPCLFLANLPLLCLWPRLAIEIVYICPAIHQRFFELGLLLACTIFALSVVSRALEVSAVFMSPFFIFLALGSGSLAGARRNQIYTSGLERRRSIFCARGDHSVASLKETLHKCPWDLLAISALTVLVVCVMIVLHVHAEVFFGLSRYLPLFLCGAMASGGLYLGHSSIIACVMATLCTLTSVVVYFLHETLGPLGKTVLFISIFVYYFSGVAALSAAMRYKLKKFVNGPLVHLRVVYMCCFVFTFCEYLLVTFIKS
What is the function of this protein?
Facilitates virus attachment to oral epithelial cells by binding to host beta1 integrin family.  Participates in rearrangement of cellular actin to increase intercellular contacts by binding BDLF2 and thereby promote virus cell-to-cell spreading.
What are the official names of this protein?
Protein BMRF2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae BMRF2 family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host cell membrane; Multi-pass membrane protein. Note=In EBV-infected polarized oral epithelial cells, is transported to the basolateral membranes and colocalizes with beta1 integrin.
Protein: PHLA_MYCTO
Sequence: MSASPLLGMSRREFLTKLTGAGAAAFLMDWAAPVIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYFGTLSSTNGFNAASPAFQQMGWNPMTQALDPAGVTIPFRLDTTRGPFLDGECVNDPEHQWVGMHLAWNGGANDNWLPAQATTRAGPYVPLTMGYYTRQDIPIHYLLADTFTICDGYHCSLLTGTLPNRLYWLSANIDPAGTDGGPQLVEPGFLPLQQFSWRIMPENLEDAGVSWKVYQNKGLGRFINTPISNNGLVQAFRQAADPRSNLARYGIAPTYPGDFAADVRANRLPKVSWLVPNILQSEHPALPVALGAVSMVTALRILLSNPAVWEKTALIVSYDENGGFFDHVTPPTAPPGTPGEFVTVPNIDAVPGSGGIRGPLGLGFRVPCIVISPYSRGPLMVSDTFDHTSQLKLIRARFGVPVPNMTAWRDGVVGDMTSAFNFATPPNSTRPNLSHPLLGALPKLPQCIPNVVLGTTDGALPSIPYRVPYPQVMPTQETTPVRGTPSGLCS
What is the function of this protein?
Involved in virulence (PubMed:12100560).  Induces cytotoxic effects on mouse macrophage cell lines, via direct or indirect enzymatic hydrolysis of cell membrane phospholipids (By similarity).  Hydrolyzes phosphatidylcholine (PubMed:12100560).
What are the official names of this protein?
Phospholipase C A, PLC-A, MTP40 antigen.
What is the protein family that this protein belongs to?
Belongs to the bacterial phospholipase C family.
What are the subcellular locations of this protein?
Secreted, cell wall. Note=Remains associated with the cell.
Protein: PYRE_ECOBW
Sequence: MKPYQRQFIEFALSKQVLKFGEFTLKSGRKSPYFFNAGLFNTGRDLALLGRFYAEALVDSGIEFDLLFGPAYKGIPIATTTAVALAEHHDLDLPYCFNRKEAKDHGEGGNLVGSALQGRVMLVDDVITAGTAIRESMEIIQANGATLAGVLISLDRQERGRGEISAIQEVERDYNCKVISIITLKDLIAYLEEKPEMAEHLAAVKAYREEFGV
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: OBG_SALRD
Sequence: MKFLDQVDLRVSSGDGGKGVVAWRREKYVPKGGPSGGDGGDGGSVYVEADENLYTLMDLSHNTQVFAEDGEPGGRREQTGASGEDKVIRVPPGTVVKTQTGEVLGEVVEPGQRICVAEGGQGGRGNAFFKSSTNQAPRESQPGEPGEERDLTFELKLMADVGLVGFPNAGKSTLVSSVSAAEPEVADYPFTTLTPQLGMVYVSEYETFVMADIPGIIEDAHEGKGLGLQFLRHIERTSVLLFVIPITSQDLGEEYEALLHELESHEASLLDKPRVVALSKIDILAPDERALLPDVVADEFPDDVPLLPISAVADVGLDQLKYTLFDTVHSTQSADAIDA
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIQ_LUPPO
Sequence: MQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGF
What is the function of this protein?
Ubiquitin exists either covalently attached to another protein, or free (unanchored).  When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains).  Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degradation via the proteasome.  Linear polymer chains formed via attachment by the initiator Met lead to cell signaling.  Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed.  When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).
What are the official names of this protein?
Ubiquitin.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.