PharMolix/UniProtQA huggingface dataset:
Protein: SYK_TOLAT
Sequence: MSEQNQTPDAELDVQEFNNEMTQRRAKLAELRTKGNPFPNDFRRDQISNELHAAFDDKSQDELAAEKHYVKIAGRIMTRRIMGKASFATLQDMGGKIQIYVTRDDLPEGFYNEQFKKWDLGDIVGVEGYMFRTNTGELSVHTTSIRLLTKALRPLPEKHKGLTDQEARCRQRYLDLIANEESRRTFQIRNQVMNGIRNFLNSKNFMEVETPMMQVIPGGASARPFVTHHNALDIDMYLRIAPELYLKRLVVGGFERVYEVNRNFRNEGISVRHNPEFTMLEFYMAYADYNDLMDLTEEMLRTLAQNIHGTTKIRYAKDGEEGIEIDFGQPFARMTMVESILKYGNDVKAEELTTLEGAIAVAKRHHVELMKSWELGHVITAIFEETAEHMLHQPTFITEYPAAVSPLARRNDDNPEVTDRFEFFIGGREIANGFSELNDAEDQAERFQAQVAQKEAGDDEAMFYDADFVTALEHGLPPTAGQGIGIDRLVMLFTNSHTIRDVILFPALRPSNK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLAS_SOLTU
Sequence: LDVLLGGDDGSLAFIPGNFSVSAGEKITFKNNAGFPHNVVFDEDEIPAGVDASKISMAEEDLLNAAGETYSVTLSEKGTYTFYCAPHQGAGMVGKVTVN
What is the function of this protein?
Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I.
What are the official names of this protein?
Plastocyanin.
What is the protein family that this protein belongs to?
Belongs to the plastocyanin family.
Protein: HESB_NOSS1
Sequence: MTVTLTEKAEFRLRAFLRGSAKDANETTKGIRVSVKDGGCSGYEYLMDVTSQPQPDDLVTQQGSVLVYVDAKSAPLLEGIVIDFVEGLVESGFKFTNPNATSTCGCGKSFKVGDCSPEGVPCS
What is the function of this protein?
May be required for efficient nitrogen fixation.
What are the official names of this protein?
Protein HesB.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: DPAS_CATRO
Sequence: MAGKSAEEEHPIKAYGWAVKDRTTGILSPFKFSRRATGDDDVRIKILYCGICHTDLASIKNEYEFLSYPLVPGMEIVGIATEVGKDVTKVKVGEKVALSAYLGCCGKCYSCVNELENYCPEVIIGYGTPYHDGTICYGGLSNETVANQSFVLRFPERLSPAGGAPLLSAGITSFSAMRNSGIDKPGLHVGVVGLGGLGHLAVKFAKAFGLKVTVISTTPSKKDDAINGLGADGFLLSRDDEQMKAAIGTLDAIIDTLAVVHPIAPLLDLLRSQGKFLLLGAPSQSLELPPIPLLSGGKSIIGSAAGNVKQTQEMLDFAAEHDITANVEIIPIEYINTAMERLDKGDVRYRFVVDIENTLTPPSEL
What is the function of this protein?
Component of the seco-iridoid and derivatives monoterpenoid indole alkaloids (MIAs, e. g.  vinblastine, catharanthine, tabersonine, vincadifformine, vindoline, vincristine, quinine and strychnine) biosynthesis pathway.  Converts precondylocarpine acetate to dihydroprecondylocarpine acetate.
What are the official names of this protein?
Dehydroprecondylocarpine acetate synthase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: ACKA_CLAMS
Sequence: MPVVLVVNSGSSSFKYQLIEMDTETVLASGLVERIGEEVGSTRHKAGGDSWERELPIADHTAGFQAMLDAFADHGPSLEEGPPVAIGHRVVHGGDVFVEPTVVTEKVKADIDDLSALAPLHNPGALQGIQAAQTAFPDVAHVAVFDTAFHQTLPAEAYTYAIDRELAAAHRIRRYGFHGTSHKYVSEAAARLLGKPLEETRIIVLHLGNGASAAAVQGGRSIDTSMGLTPLEGLVMGTRSGDIDPAILFHLARHTDLGLDDLETLLNRKSGLLGLTGLGDMRDVQRAAADGDEDAQTALGVYRHRIRHYVGAYAAQLGGVDAVVFTAGVGENNPLVRRRSLAGLEFMGIGIDDDRNELISSEARFVSPDGSPVAVLVIPTDEELEIARQSLAATGN
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRIK4_RAT
Sequence: MPRVSAPLVLLPAWLLMVACSPHSLRIAAILDDPMECSRGERLSITLAKNRINRAPERLGKAKVEVDIFELLRDSEYETAETMCQILPKGVVAVLGPSSSPASSSIISNICGEKEVPHFKVAPEEFVRFQLQRFTTLNLHPSNTDISVAVAGILNFFNCTTACLICAKAECLLNLEKLLRQFLISKDTLSVRMLDDTRDPTPLLKEIRDDKTATIIIHANASMSHTILLKAAELGMVSAYYTYIFTNLEFSLQRMDSLVDDRVNILGFSIFNQSHAFFQEFSQSLNQSWQENCDHVPFTGPALSSALLFDAVYAVVTAVQELNRSQEIGVKPLSCGSAQIWQHGTSLMNYLRMVELEGLTGHIEFNSKGQRSNYALKILQFTRNGFRQIGQWHVAEGLSMDSRLYASNISDSLFNTTLVVTTILENPYLMLKGNHQDMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYGVPEANGTWTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRRPGYFSSLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPHPCAQGRCNLLVNQYSLGNSLWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPIESVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVLNSNYAFLLESTMNEYYRQRNCNLTQIGGLLDTKGYGIGMPVGSVFRDEFDLAILQLQENNRLEILKRKWWEGGKCPKEEDHRAKGLGMENIGGIFVVLICGLIVAIFMAMLEFLWTLRHSEASEVSVCQEMMTELRSIILCQDNIHPRRRRSGGLPPQPPVLEERRPRGTATLSNGKLCGAGEPDQLAQRLAQEAALVARGCTHIRVCPECRRFQGLRARPSPARSEESLEWDKTTNSSEPE
What is the function of this protein?
Receptor for glutamate.  L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.  The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists.  This receptor binds kainate > quisqualate > glutamate >> AMPA.
What are the official names of this protein?
Glutamate receptor ionotropic, kainate 4, GluK4, Glutamate receptor KA-1, KA1.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK4 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein.
Protein: DAFT_TRYCR
Sequence: EFGILEDGETIFVYVNGQMLGSSKTMPTGKERLLDISHFYFGGDNGEEKGNRHVKVRNVLLYNRVLSASELQCRLPEEVVQKPQSASPTYLKARI
What is the function of this protein?
Interferes with the efficient assembly of the host C3 convertase.  Could protect parasites from complement-mediated lysis by sera from a number of different species.
What are the official names of this protein?
Trypomastigote decay-accelerating factor, T-DAF.
What is the protein family that this protein belongs to?
Belongs to the receptors of complement activation (RCA) family.
Protein: RPOZ_MYCA1
Sequence: MTNSQSDAALAAVPDRFDPSAGGPGAYDTPLGITNPPIDELLDRVSSKYALVIYAAKRARQINDYYNQLGEGILEYVGPLVEPGLQEKPLSIALREIHGDLLEHTEGE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: AMPA_ECO5E
Sequence: MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_CLOBJ
Sequence: MLKGRNLLDPMDFSLEELEEVFKLADEIIEEPEKFLHVCDGKILATLFYEPSTRTRFSFEAAMLRLGGQVIGFSEPNSSSVAKGESVADTIRTVGCYADIAAMRHPKEGAPAIAAMYSDIPVINAGDGSHQHPTQTLTDLLTIRSLKGDLSNLTIGCCGDLKFGRTVHSLVKALSRYKNNKFVFMSPEELKIPDYIRKEILEKNNIEYKEISKMEDAMAELDILYMTRVQRERFFNEDDYVRLKDSYILDGEKMKYAKKDMMVLHPLPRVNEIAYEIDQDPRGCYFKQAKYGMYVRMALIAKLLGVR
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: VKT6_CRYNI
Sequence: MSSGGLLLLLGLLTLWEVLTPVSSTDRPDFCELPEDSGSCKGNFEAFYYNSDQHQCLEFIYGGCDGNANNFKTIEECKLTCAA
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Kunitz-type serine protease inhibitor nigrescinin-6.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: GADC_ECOLI
Sequence: MATSVQTGKAKQLTLLGFFAITASMVMAVYEYPTFATSGFSLVFFLLLGGILWFIPVGLCAAEMATVDGWEEGGVFAWVSNTLGPRWGFAAISFGYLQIAIGFIPMLYFVLGALSYILKWPALNEDPITKTIAALIILWALALTQFGGTKYTARIAKVGFFAGILLPAFILIALAAIYLHSGAPVAIEMDSKTFFPDFSKVGTLVVFVAFILSYMGVEASATHVNEMSNPGRDYPLAMLLLMVAAICLSSVGGLSIAMVIPGNEINLSAGVMQTFTVLMSHVAPEIEWTVRVISALLLLGVLAEIASWIVGPSRGMYVTAQKNLLPAAFAKMNKNGVPVTLVISQLVITSIALIILTNTGGGNNMSFLIALALTVVIYLCAYFMLFIGYIVLVLKHPDLKRTFNIPGGKGVKLVVAIVGLLTSIMAFIVSFLPPDNIQGDSTDMYVELLVVSFLVVLALPFILYAVHDRKGKANTGVTLEPINSQNAPKGHFFLHPRARSPHYIVMNDKKH
What is the function of this protein?
Involved in glutaminase-dependent acid resistance (PubMed:8682809, PubMed:30498489).  Exchanges extracellular glutamate (Glu) for intracellular gamma-aminobutyric acid (GABA) under acidic conditions (PubMed:22407317, PubMed:23589309).  The protonation states of substrates are crucial for transport.  Selectively transports Glu with no net charge and GABA with a positive charge (PubMed:23589309).  Also efficiently transports glutamine and, to a smaller extent, methionine and leucine (PubMed:22407317).  When the extracellular pH drops below 2. 5, can import L-glutamine and export either glutamate or GABA (PubMed:30498489).  The ability to survive the extremely acidic conditions of the stomach is essential for successful colonization of the host by commensal and pathogenic bacteria (PubMed:8682809, PubMed:30498489).
What are the official names of this protein?
Glutamate/gamma-aminobutyrate antiporter, Glu/GABA antiporter, Extreme acid sensitivity protein.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Glutamate:GABA antiporter (GGA) (TC 2.A.3.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYW_PSEPK
Sequence: MTTRILTGITTTGTPHLGNYAGAIRPAIRASQQPGVDSFYFLADYHALIKCDDPLRIQRSRLEIAATWLAGGLDPDKVTFYRQSDIPEIPELTWLLTCVAAKGLLNRAHAYKASVDKNVENGEDPDAGVTMGLFSYPVLMAADILMFNANKVPVGRDQIQHVEMARDIGQRFNHLFGQGKDFFALPEAVIEESVATLPGLDGRKMSKSYDNTIPLFTSAKDMKDAISRIVTDSRAPGEAKDPDNAHLFTLYQAFSTPEQCAGFREELLQGLGWGDAKQRLFQLLDGQLAEKREYYHQLIARPADLEDILLAGAAKARKIATPFLEQLREAVGLRSFRSSVQATAEVKKKATKSARFVSFRDEDGSFRFRLLAADGEQLLLSRSFADGKSAGAVSKQLQQGGEADVRIEGLSFGLWLNGEQVADGPQFDNAEARDAAIQSLNEALAPQQD
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK1_THAPS
Sequence: MRKLSRRQNENLKKIKNVVHSSLEEAITLLQDTATAKFIESVELHANLNIDTKYADQQLRTTVTLPHGIGKSMRIAVLTNEANFNEANEGGADIVGSQELIDDISQGNLNFDLLVATPDMMPKLAKLGRVLGPKGLMPSPKSGTVSTNLTETLSDFKKGKFEYKADKTGVVHVNFGKANFSKDQLMENLTSLYQSIEQNRPSGVKGKYFKSLFICTSMGPSIQLDLNTFD
What is the function of this protein?
Binds directly to 23S rRNA.  Might be involved in E site tRNA release (Potential).
What are the official names of this protein?
50S ribosomal protein L1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CH10_RUEST
Sequence: MALKPLHDRVLVRRTESEEKTAGGLIIPDSAKEKPSEGVVVACGEGARKDSGELIAMAVKEGDNILFGKWSGTEVTVDGEELLMMKESDIMGVIV
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NART_STAAW
Sequence: MYKTKGGFQLTLQTLSLVVGFMAWSIIAPLMPFIKQDVNVTEGQISIILAIPVILGSVLRVPFGYLTNIVGAKWVFFTSFIVLLFPIFFLSQAQTPGMLMASGFFLGVGGAIFSVGVTSVPKYFPKEKVGLANGIYGMGNIGTAVSSFLAPPIAGIIGWQTTVRSYLIIIALFALIMFIFGDTQERKIKVPLMAQMKTLSKNYKLYYLSYWYFITFGAFVAFGIFLPNYLVNHFGIDKVDAGIRSGVFIALATFLRPIGGILGDKFNAVKVLMIDFVVMIIGAIILGISDHIALFTVGCLTISICAGIGNGLIFKLVPSYFLNEAGSANGIVSMMGGLGGFFPPLVITYVANLTGSSHLAFIFLAVFGCIALFTMRHLYQKEYGSLKNG
What is the function of this protein?
Probably required for nitrate uptake under anoxic conditions.  Also possibly involved in excretion of nitrite produced by the dissimilatory reduction of nitrate (By similarity).
What are the official names of this protein?
Probable nitrate transporter NarT.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PLSY_RALPJ
Sequence: MSPVVATVIFALAAYLIGSISFAVVVSRAMGLADPRTYGSGNPGATNVLRSGNKKAAILTLLGDAAKGGLAVWLAQWLAPRFGVDETGIALVVIAVFLGHLFPVFHRFEGGKGVATAAGILLALNVWLGLATLATWLIIAVFFRYSSLAALVSAVFAPFFYVLMNGFDWIAGAVALMAVLLIARHRANIAKLLAGKESRIGEKKKAA
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CA185_BOVIN
Sequence: MASPNGFFNHLTYFLAAGAVTLGIGFFALASALWFLICKRREIFQDSKFKAVDEKCRQRPSKAKIKSHPQCVFISRNFHTGRFQSQEEQRKKETACIKANNGYSKDDFCLATKKVICDPSESSSATNPSSVTLSLSTLPSDFYYSQSVEIADDWYSDDSQMKKSPSMPFLGEPLMEKVFSYLTTIPLEQCTENVLNMTLRDDQKDDNLKEIFTQRNTEVEIQNLQHNTE
What are the official names of this protein?
Uncharacterized protein C1orf185 homolog.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: KEFF_KLEAE
Sequence: MILIIYAHPYPQHSHANKRMLEQAGTLEGVEIRSLYQLYPDFNIDVAAEQAALARADLVIWQHPMQWYSVPPLLKLWMDKVLSHGWAYGHNGIALRGKSLMWAVTTGGGESHFDIGSFPGFPVLAQPLQATALYCGMKWLPPFAMHCTFICDDETLQAQARRYRQRLIDWQEAHQNG
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefC.  Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefF, Quinone oxidoreductase KefF.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SECA_GEOMG
Sequence: MFGSIIKKIVGSKNERELKRLWPIVEKINGLEPQMAALTDDQLRNKTSEFKERCAKGESLDSLLPEAFAVCREAGKRVHNMRHFDVQLIGGMVLHSGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDSDWMGRIYNFLGLSVGVIVHGLDDEERREAYAADITYGTNNEFGFDYLRDNMKFSLDDYVQRPFYFSIVDEVDSILIDEARTPLIISGPTEDSTDKYYIIDRVIPHLKKGEMKEVEANTLSGKKKEYTGDFTVDEKARSATLTEEGVLKVEKLLKIDNLYDPRHMEFLHHVNQALRAHALFRRDVDYVVKEGEVIIVDEFTGRLMPGRRWSDGLHQAIEAKEGVEIENENQTLATITFQNYFRMYEKLSGMTGTADTEAEEFHKIYKLDVTVIPTNRPLLRPDFPDVIYKTEREKFAAVIEEIKDCHQKGQPVLVGTISIEKSEILSELLKKQGIPHNVLNAKQHEREAEIVAQAGRKGMLTIATNMAGRGTDIVLGGNPDSLAKQWRRENPDAADEEYAAILAKYKAECAAEHDEVVKLGGLHILGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLEDDLLRIFGSERVSKIMDFLKIEEGEAITHGMITKAIENAQKKVEAHNFEIRKHLIEYDDVMNKQREVIYTQRREILAGEDIRGNFTQMLDDTIEDIAAAFAIDKVHASEWDWQAIVEAVYKTFGFQIDIPAETMDRLAPESFRKLLKESVHEAYEGKLASFGDELMDHLIKVIMLQAIDSQWKDHLLSIDHLKEGIGLRGYGQKDPKQEYKKEAYRLFMDMMARIAEETVEKIFWVQIAREEDVERMEEEQQQQAQKKIVFNLGEEPATAPQPARSKKSASRNDPCPCGSGKKYKKCCGK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: SYA_METTH
Sequence: MITMSHQLEKLGYRKYECRSCGNTFWSMKERATCGDAPCDEYGFIGNPATDRSYDLYEIQDKFMEFFAERGHEPIRRYPVLAKRWRDDVFLVGASIYNFQPWVTSGLVKPPANPLVVAQPSIRLNDVDNVGRTGRHLTCFTMGGHHAFNSEDNTVYWEEETIKYCHDFLTHIGIDPSEITFIESWWQGGGNEGPCYEVCVRGVELATLVFIQYRTLPDGGREEIPLKIVDTGYGLERFAWISQGTPTAYDACLGPVIEKLVELTGVKIDEEILAENAQVAGMMDIETYADLRELRKRVADKLGISVEELERAAAPMESVYAIADHTRCLAFMLADGVIPSNVKEGYLARLIIRRTLRLMKDLGMKESLKDIMNIQVEFLEGHYPEIRSHHEHILNIIDLEEHRYARTVKRGRRIVEKTIKYLKRDGKAEMPLEILIKLYDSHGIPPETIGEIAEESGFQVKIPDNFYTLVAERNETETEMPEEDVHLDYPATELLFYDEPDDLEFQAEVIGIHENGLILDRTLFYPEGGGQPSDTGYITAEGCRLRIKHAEKIGAVVVHRTDDEICIEPGTTIRGFIDSDRRLQLTRNHTATHLIVSAARKVLGDHIWQAGAQKGVKSSRLDLSHYRRITLEELQEIERLANEYVMMNVPLKVRWMDRDLAERKYGFILYQGGVVPGSRIRVVEIPGVDVQACAGTHVHRTGDIGLIRINRTERIQDGVERIEFSAGSAAIEIMQKTGDILRESSDIFKVTPSQLPGTCERFFTEWKALRNEVSRLKEKVASLKILEMKDRAERINDLTVIIDTVDADMDEMKNMALELSATVDAVVLANPEGKIVGAASEDAVKAGLRINEVISQAAAVLGGGGGGRPHLAQGAGPATDKVDEALEEARAALSTVRN
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFEU_YERPA
Sequence: MFVPFLIMFREGLEAALIVSLIASYLKRTQRGQWMGAVWVGVVVAAVLCLAIGIFINETTGEFPQKQQELFEGIIAVVAVCILTYMVFWMRKVSKSVKVHLEGAIDNALNSGRGQGWALVAMVFFAVAREGLESVFFLLAAFQQDVGIGAPIGAILGLVCAILVGMAIYWGGVKLHLAKFFKWTSLFILFVAAGLAAGAIRAFHEAGLWNHFQDIAFDLTDVLSTHSLLGTFLEGMFGYQEAPTVSEVSVYFIYLIPALILFFLPPRSTAGSAIAAARKINP
What is the function of this protein?
Uptake of Fe(2+) ions across the membrane.
What are the official names of this protein?
Ferrous iron permease EfeU, Fe(2+) ion permease EfeU, Ferrous iron uptake protein.
What is the protein family that this protein belongs to?
Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRMB_BACCQ
Sequence: MRLRHKPYAMDRINEYSHIVIGNPEERAGNWKEVFGNEQPIHIEVGTGRGRFMYDMAKANPHINYIGIEKFTSVVVDALDKLIEEELPNLKLINKDAEDLTVFFAKGEIDRVYLNFSDPWPKKRHTKRRLTYKTFLRNYEEVLVEGGEIHFKTDNQGLFEYSLMSMAEYGMLLTYLSLDLHNSDFEGNIMTEYEEKFSSKGHRIYRVEAKYRTEPMQ
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: PUS10_THEAC
Sequence: MFQISELANYRLCKRCSGRIFAYHYHGISNLERGEYLQFAIGCETGNPDFSFVDSKNCDICHGIFDRFDDIYDLVAKKVGDAQYSTFLVGSVFPQDTIRMEEDIQKKFGSSGESIKKEFNREFGKYFSARTGKEYSQDNPDLTILVNAEYLFVDVKIRSIYIYGKYRKFRRDMPQTRWIHRPNGDTVESVIGSVFTRYAGGTNYYLHGSGREDVDVRMLGNGREFVLEVENPRYREFELDPVVKEINTSGKGVEIFDVKFSSHDAVSEVKLEKHRKVYDALVVSDRPIDESRLLEACINLTGKNIYQRTPLRVAQRRSDLVRTRRIDQVDLVGVSANEAEILISAEAGTYIKELVNGDGGRTRPSLSEMYGSPLNVKELDVIKICRGED
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase Pus10, tRNA pseudouridine 54/55 synthase, Psi54/55 synthase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase Pus10 family.
Protein: PLIA8_BOTMO
Sequence: MRLILLSSLLLLGIFLANGDEVDPDGKVLNSLIYGVMHLQREFANLKGAFLTVHRARSFGSGSERLYVTNKEIKNFEALRQICEQAEGHIPSPQLENQNKAFANVLERHGKEAYLVVGDSANFTNWAAGEPNKAAGTCVKADTHGSWHSASCDDNLLVVCEFYFIL
What is the function of this protein?
This phospholipase A2 inhibitor binds directly phospholipase A2 in the presence or absence of calcium.
What are the official names of this protein?
Phospholipase A2 inhibitor clone 08, alpha-PLI.
What is the protein family that this protein belongs to?
Belongs to the alpha-type phospholipase A2 inhibitor family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in plasma.
Protein: RECR_ECO27
Sequence: MQTSPLLTQLMEALRCLPGVGPKSAQRMAFTLLQRDRSGGMRLAQALTRAMSEIGHCADCRTFTEQEVCNICSNPRRQENGQICVVESPADIYAIEQTGQFSGRYFVLMGHLSPLDGIGPDDIGLDRLEQRLAEEKITEVILATNPTVEGEATANYIAELCAQYDVEASRIAHGVPVGGELEMVDGTTLSHSLAGRHKIRF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: HRCA_RHOPB
Sequence: MAHHDPIGLIAPNAGLAQLNERSREIFRQIVESYLATGEPVGSRNISRLITVPLSPASVRNVMSDLEQLGLIYAPHTSAGRLPTELGLRFFVDALMQVGDLTEPERQSIQAQLASVGRAQSVEAALGEALTRLSGLTRAAAVVLTAKSNARLKHIEFVRLEPERALVVLVSEDGQVENRVLTLAAGVPSSALIEASNFLNARIRGRTLAEARLELETALSQDRAELDQLTQKVISAGIASWSGGANDDRQLIVRGHANLLEDLHALDDLERVRLLFDDLETKRGVIDLLGRAESAEGVRIFIGSENKLFSLSGSSTIIAPYSDGAGHIVGVLGVIGPTRLNYARVIPMVDYAARVVSQMLGG
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: ENO_HERAR
Sequence: MSAIVDIIGREIIDSRGNPTVECDVLLESGVMGRASVPSGASTGSREAIELRDGDKNRYFGKGVLKACENINTEISEAIMGLDANEQAFLDRTLIDLDGTDNKARLGANATLAVSMAVAKAAAEESGLPLYRYFGGSGAMQMPVPMMNVINGGAHANNNLDLQEFMIIPVGAPSFREAIRYGAEVFHTLKKIINDKGLPTSVGDEGGFAPSVENHEAAIKMILQAIEQAGYEPGTQIALGLDCAASEFYKDGKYHLAGEGMSLSSADFTNLLGTWCDKYPIISIEDGMAENDWDGWATLTNALGKKVQLVGDDLFVTNTKILREGIQKNVANSILIKINQIGTLTETFAAIEMAKRAGYTAVISHRSGETEDSTIADIAVGTNSLQIKTGSMSRSDRMAKYNQLLRIEEDLGDIASYPGRNAFYNLK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.