PharMolix/UniProtQA huggingface dataset:
Protein: REB1_YEAST
Sequence: MPSGHNDKNANQESVEEAVLKYVGVGLDHQNHDPQLHTKDLENKHSKKQNIVESSSDVDVNNNDDSNRNEDNNDDSENISALNANESSSNVDHANSNEQHNAVMDWYLRQTAHNQQDDEDDENNNNTDNGNDSNNHFSQSDIVVDDDDDKNKKDAGVGVDDDHQSMAMAAVAAAYTLSKNNNNNNSIANDSNSRKRQHDNGNNHENSQKKRKNNNDDDDRQIGNVDPELTTLGDADDNDTNNDVIDRDQLVHKAIIDADSITQHPDFQQYLNTAADTDDNEKLKHIKDHLMRTHGLNHQNKNHNDDTDDLSNSTKQYSELQKDSMLDSSLNKSRNYMEVLPKVISQDTQPHQQKSPSHDNEAGSVDNSEISQLLQSAATKASSLVSLSSSSATPSTSRSNNSKAFDKAEDAALERFINEYEAIERLTRQQVCERIWSSDRPKDNFWNNIYKVLPYRSSSSIYKHMRRKYHIFEQRGKWTAEEEQELAKLCAEKEGQWAEIGKTLGRMPEDCRDRWRNYVKCGTNRASNRWSVEEEELLKKVISDMLEEAQQQQSQLHPNLLEEEQHLLQDDQNDHRNNDEDDDDTASAAAAAAAAIQEQQQLLQQKQQDDDDAIAAAAAAASSSLGDNKDEDKPHDSLGIQLDDNSQNSMVPAPSATSTHSKSLSNTIRRHNNKLRKSLMGNGKLDFKDIINWTIVSERMGGTRSRIQCRYKWNKLVKREAIAKIQTVKDDDMLWIFEKLRDLGITEDSQVDWDELAALKPGMKLNGLELKLCYERMKKKVKGYKQKSINEISKELVDYFSSNISMKTEN
What is the function of this protein?
DNA-binding protein that recognizes sites within both the enhancer and the promoter of rRNA transcription, as well as upstream of many genes transcribed by RNA polymerase II.  It is essential for cell growth.  May stimulate or inhibit transcription.  Specifically recognizes the sequence 5'-CCGGGTA-3' or 5'-CGGGTRR-3' (where R is any purine).  A member of the general regulatory factors (GRFs) which act as genome partitioners.  Acts as a chromatin insulator which are known as STARs (Subtelomeric anti-silencing region).  STARs prevent negative or positive transcription influence by extending across chromatin to a promoter.
What are the official names of this protein?
DNA-binding protein REB1, QBP.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y4IQ_SINFN
Sequence: MKNVHNTIDEARLGIMLNDLRLPTIKTLWPQFAEQADREGWPAARFLSAIAEHELAERAHRRIERHLAEAHLPPGKTLESFAFDAVPMVSKAQVMAIAAGDSWLAKGANILLFGPPGGGKSHLAAAIGLALIENGWRVLFTRTTDLVQKLQVARRELQLESAIAKLDKFDLLILDDLAYVTKDQAETSVLFELISARYERRSIMITANQPFGEWNRVFPDPAMTLAAVDRLVHHATIFEMNVESYRRRSAMEAKRHRGRPAAFATTKSASLIVAERQSEHDETLASDNQHDTFMPTAT
What are the official names of this protein?
Putative insertion sequence ATP-binding protein y4iQ/y4nD/y4sD.
What is the protein family that this protein belongs to?
Belongs to the IS21/IS1162 putative ATP-binding protein family.
Protein: ELOF1_DICDI
Sequence: MGKRKSSKPPPKKVVQKLPKHFDCLFCAHSQSVDCILDRELGKGVAKCRVCNASYETPIHELSDAIDVYSDWIDACESIR
What is the function of this protein?
Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.
What are the official names of this protein?
Transcription elongation factor 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the ELOF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BH074_ARATH
Sequence: MGGESNEGGEMGFKHGDDESGGISRVGITSMPLYAKADPFFSSADWDPVVNAAAAGFSSSHYHPSMAMDNPGMSCFSHYQPGSVSGFAADMPASLLPFGDCGGGQIGHFLGSDKKGERLIRAGESSHEDHHQVSDDAVLGASPVGKRRLPEAESQWNKKAVEEFQEDPQRGNDQSQKKHKNDQSKETVNKESSQSEEAPKENYIHMRARRGQATNSHSLAERVRREKISERMRLLQELVPGCNKITGKAVMLDEIINYVQSLQQQVEFLSMKLATVNPEINIDIDRILAKDLLQSRDRNTPTLGLNPFAGFQGNIPNLSATTNPQYNPLPQTTLESELQNLYQMGFVSNPSTMSSFSPNGRLKPEL
What is the function of this protein?
Transcriptional activator involved in cell elongation.  Regulates the expression of a subset of genes involved in cell expansion by binding to the G-box motif.  Binds to chromatin DNA of the FT gene and promotes its expression, and thus triggers flowering in response to blue light (PubMed:24130508).
What are the official names of this protein?
Transcription factor bHLH74, Basic helix-loop-helix protein 74, AtbHLH74, bHLH 74, Protein ACTIVATOR FOR CELL ELONGATION 2, Transcription factor EN 90, bHLH transcription factor bHLH074.
What are the subcellular locations of this protein?
Nucleus.
Protein: MCTS1_HUMAN
Sequence: MFKKFDEKENVSNCIQLKTSVIKGIKNQLIEQFPGIEPWLNQIMPKKDPVKIVRCHEHIEILTVNGELLFFRQREGPFYPTLRLLHKYPFILPHQQVDKGAIKFVLSGANIMCPGLTSPGAKLYPAAVDTIVAIMAEGKQHALCVGVMKMSAEDIEKVNKGIGIENIHYLNDGLWHMKTYK
What is the function of this protein?
Anti-oncogene that plays a role in cell cycle regulation; decreases cell doubling time and anchorage-dependent growth; shortens the duration of G1 transit time and G1/S transition.  When constitutively expressed, increases CDK4 and CDK6 kinases activity and CCND1/cyclin D1 protein level, as well as G1 cyclin/CDK complex formation.  Involved in translation initiation; promotes recruitment of aminoacetyled initiator tRNA to P site of 40S ribosomes.  Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits.  Plays a role as translation enhancer; recruits the density-regulated protein/DENR and binds to the cap complex of the 5'-terminus of mRNAs, subsequently altering the mRNA translation profile; up-regulates protein levels of BCL2L2, TFDP1, MRE11, CCND1 and E2F1, while mRNA levels remains constant.  Hyperactivates DNA damage signaling pathway; increased gamma-irradiation-induced phosphorylation of histone H2AX, and induces damage foci formation.  Increases the overall number of chromosomal abnormalities such as larger chromosomes formation and multiple chromosomal fusions when overexpressed in gamma-irradiated cells.  May play a role in promoting lymphoid tumor development: lymphoid cell lines overexpressing MCTS1 exhibit increased growth rates and display increased protection against apoptosis.  May contribute to the pathogenesis and progression of breast cancer via promotion of angiogenesis through the decline of inhibitory THBS1/thrombospondin-1, and inhibition of apoptosis.  Involved in the process of proteasome degradation to down-regulate Tumor suppressor p53/TP53 in breast cancer cell; Positively regulates phosphorylation of MAPK1 and MAPK3.  Involved in translation initiation; promotes aminoacetyled initiator tRNA to P site of 40S ribosomes.  Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits.
What are the official names of this protein?
Malignant T-cell-amplified sequence 1, MCT-1, Multiple copies T-cell malignancies.
What is the protein family that this protein belongs to?
Belongs to the MCTS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Nuclear relocalization after DNA damage.
Protein: FETAF_PROFL
Sequence: MNSLVALVLLGQIIGSTLSSQVRGDLECDDKEAKNWADDAVRYINEHKLHGHKQALNVIKNICVVPWNGDLVAVFLELNLLETECHVLDPTPVEKCTVRQQHNHAVEMDCDAKIMFNVETFKRDVFVKCHSTPDSVENVRRNCSKCPILLPPNNPHVVDSVEYVLNKHNEKLSGHIYEVLEISRGQHKYEPEAYYLEFVIVEINCTAQEAHDDHHQCHPYTAGEDHIAFCRSTVFRSHASLEKPKDEKFESNCVILDVKDGHAHSHLIQQHIEKNSISPEHNITILNFVHPDDHTSTSHESHEHVAEVPVVFVKKELPTDISDHHTTPVKGCPGKVHHFKLY
What is the function of this protein?
Inhibits hemorrhagic and proteolytic activities of metalloproteinases (HR1A, HR1B, HR2a, HR2b and H2 proteinase from T. flavodidis and brevilysins H3, H4, H6 and L4 from A. halys brevicaudus).  Has no effect on brevilysins H2.  Has no effect on papain and cathepsin-B.
What are the official names of this protein?
Antihemorrhagic factor HSF, Habu serum factor, Metalloproteinase inhibitor.
What is the protein family that this protein belongs to?
Belongs to the fetuin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FABZ_NITWN
Sequence: MESPVRFEHVDIATILKTLPHRYPFLLIDRVLNIRADHSGIGVKNVTFNEPAFQGHFPERPVYPGVLMIEGMAQTAGVIGIMSVEGTEKPRAVYFLTIDKCKFRKPVMPGDIVEYHMRSIGRRKTMWWFHGDAKVNGTIVAEADVGAMLTD
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP40_EBORE
Sequence: MRRGVLPTAPPAYNDIAYSMSILPTRPSVIVNETKSDVLAVPGADVPSNSMRPVADDNIDHSSHTPSGVASAFILEAKVNVISGTKVLMKQIPIWLPLGVADQKIYSFDSTTAAIMLASYTVTHFGKISNPLVRVNRLGPGIPDHPLRLLRLGNQAFLQEFVLPPVQLPQYFTFDLTALKLITQPLPAATWTDETPAGAVNALRPGLSLHPKLRPILLPGKIGKKGHASDLTSPDKIQTIMNAIPDLKIVPIDPIKNIVGIEVPELLVQRLTGKKPQPKNGQPIIPVLLPKYVGLDPISPGDLTMVITQDCDSCHSPASHPYHMDKQDSYQ
What is the function of this protein?
Plays an essential role virus particle assembly and budding.  Acts by interacting with viral ribonucleocapsid and host members of the ESCRT (endosomal sorting complex required for transport) system such as host VPS4, PDCD6IP/ALIX, NEDD4 or TGS101.  The interaction with host E3 ubiquitin ligase SMURF2 also facilitates virus budding.  May play a role in immune cell dysfunction by being packaged into exosomes that can decrease the viability of recipient cells (via RNAi suppression and exosome-bystander apoptosis).
What are the official names of this protein?
Matrix protein VP40, Ebola VP40, eVP40, Membrane-associated protein VP40.
What is the protein family that this protein belongs to?
Belongs to the filoviridae matrix protein VP40 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein. Host late endosome membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Host endomembrane system; Peripheral membrane protein. Note=In virion, localizes on the intravirional side of the membrane. In the host cell, it is found associated with virus-induced membrane proliferation foci and probably also in multivesicular bodies. These VP40-enriched membrane clusters are then redistributed to the plasma membrane where budding takes place.
Protein: HSP1_HORSE
Sequence: MARYRCCRSQSQSRCRRRRRRRCRRRRRRSVRQRRVCCRRYTVLRCRRRR
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Sperm protamine P1, Cysteine-rich protamine, Protamine ST1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: BAIP3_MOUSE
Sequence: MSTLLDIKSSVLRQVQVCPSFRRKTEQEPEVTNSQEPPTGAWKPGDGVEFFAHMRLILKKGDGRQGLPCPEVLLRSGSPAPAEPVDPNRGLRTLTQEEVEMLYEEALYTVLHRAGTMGPDQVDDEEVLLSYLQQVFGTSSEEHMEAIMRVKKAKAPTYALKVSVMRAKNLLAKDPNGFSDPYCMLGILPASSAPQEPSGQKEQRFGFRKGSKRSSPLPAKCIQVTEVKNSTLNPVWKEHFLFEIDDVNTDQLHLDIWDHDDDVSLAEACRKLNEVIGLKGMTRYFKQIVKSARANGTAGPTEDHTDDFLGCLNIPIREVPVAGADRWFKLEPRSSASRVQGDCHLVLKLITTQRDTVMSQRGRSGFLSYLLLLSRVLRFEHRVEEPNSSSWRGELSGPGTTVLCLHGAQSNLSPLQLAVLHWQVSSRHHQTRTLDYGYLLGLLEDVQAHWEEAASLPQEQEESLADSFSAFSEFGLRLLRQLRDYFPATNSTAVYRLELLLKCLEKLQLFQPAFEICPFETELSMDIAAALKRGNREWYDQLLNTKSPREQPGPQRLAGLVELADIIYEDLQLCYGVYASLFHGILKVDFFTLTFRQLERLVAEEAWVLTEELSPKMNLEVASGLFELYLTLADTQRFWSCIPGRESRSLALAGIHTPFLPAVKLWLQVLRDQAKWRLQGAVDVDTLEPVDAASKHSSSAATASLCLSHIQELWVRLAWPDPSQAQGLGTQLSQDMCEASLFYTELLRKKVDTQPGAAGEAVSEQLCVVLNNVELVRRASGQALRGLAWSEGASGLEGVLPRPLLSCIQALDEDLHREAHTVTAHLTSKMVADIRKYIQHISLSPDSIQNDEAVAPLLKYLDEKLALLNDALVKENLNRVLEALWELLLQAILQALSANRDVSADFYGRFHFTLEALVSFFHAEGQGLPLENLRDGSYKRLQEELRLHKCSTRECIEQFYLDKLKQRSLEQNRFGRLTVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQVKARTLHPVYDELFHFSVPAEACRRRGACVLFTVMDHDWLSTNDFAGEAALGLGGISGIARPHVGGGMRPGQPITLHLRRPRAQVRSALRMLEGRTSREAQEFVKKLKELEKCMEADL
What is the function of this protein?
Functions in endosome to Golgi retrograde transport.  In response to calcium influx, may interact with SNARE fusion receptors and membrane phospholipids to mediate endosome fusion with the trans-Golgi network.  By promoting the recycling of secretory vesicle transmembrane proteins, it indirectly controls dense-core secretory vesicle biogenesis, maturation and their ability to mediate the constitutive and regulated secretion of neurotransmitters and hormones.  May regulate behavior and food intake by controlling calcium-stimulated exocytosis of neurotransmitters including NPY and serotonin and hormones like insulin (By similarity).  Proposed to play a role in hypothalamic neuronal firing by modulating gamma-aminobutyric acid (GABA)ergic inhibitory neurotransmission (Probable).
What are the official names of this protein?
BAI1-associated protein 3, BAP3, Brain-specific angiogenesis inhibitor I-associated protein 3, Baiap3.
What is the protein family that this protein belongs to?
Belongs to the unc-13 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Recycling endosome membrane; Peripheral membrane protein. Late endosome membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Note=Rapidly recruited to the plasma membrane and to Golgi structures in response to increased intracellular calcium concentration.
Protein: YEIE_ECOL6
Sequence: MHITLRQLEVFAEVLKSGSTTQASVMLALSQSAVSAALTDLEGQLGVQLFDRVGKRLVVNEHGRLLYPRALALLEQAVEIEQLFREDNGAIRIYASSTIGNYILPAVIARYRHDYPQLPIELSVGNSQDVMQAVLDFRVDIGFIEGPCHSTEIISEPWLEDELVVFAAPTSPLARGPVTLEQLAAAPWILRERGSGTREIVDYLLLSHLPKFEMAMELGNSEAIKHAVRHGLGISCLSRRVIEDQLQAGTLSEVAVPLPRLMRTLWRIHHRQKHLSNALRRFLDYCDPANVPR
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YeiE.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: TRUA_NEIG2
Sequence: MDTAQKQRWAITLSYDGSRFYGWQKQAGGVPTVQAALETALARIAGESVATTVAGRTDTGVHAAAQVVHFDITAARPQQAWVRGVNAHLPEGIAVLHARQVAPGFHARFDAYGRHYRYLLESAPVRSPLLKNRAGWTHLKLDIEPMRRAAALLIGEQDFSSFRAAGCQAKSPVKTIYRTDLTQSAGLIRLDLHGNAFLHHMVRNIMGALVYVGSGRLSVEGFAALIQERSRLKAPPTFMPDGLYLTGVDYPGAYGIVRPQIPEWL
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RS3_RICRO
Sequence: MGQKVCAHGFRVGPTLIKGWDSILYAEKHYKTLFIQDLKIRDLINKGFNQAQISRVLIERPSNKSIIININAKKPNIIIGRNGSEIDKLKKAIEKMTSLKEVYINIHEVRKFNIDAAIVAQTIALQLEKRVSFRKAMKTAIQASFKQGGQGIRVSCSGRLGGAEIARTEWYIEGRMPLHTLRADIDYSTAEAITTYGVIGVKVWIYKGEYTENKRYN
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: GLMS_BACSU
Sequence: MCGIVGYIGQLDAKEILLKGLEKLEYRGYDSAGIAVANEQGIHVFKEKGRIADLREVVDANVEAKAGIGHTRWATHGEPSYLNAHPHQSALGRFTLVHNGVIENYVQLKQEYLQDVELKSDTDTEVVVQVIEQFVNGGLETEEAFRKTLTLLKGSYAIALFDNDNRETIFVAKNKSPLLVGLGDTFNVVASDAMAMLQVTNEYVELMDKEMVIVTDDQVVIKNLDGDVITRASYIAELDASDIEKGTYPHYMLKETDEQPVVMRKIIQTYQDENGKLSVPGDIAAAVAEADRIYIIGCGTSYHAGLVGKQYIEMWANVPVEVHVASEFSYNMPLLSKKPLFIFLSQSGETADSRAVLVQVKALGHKALTITNVPGSTLSREADYTLLLHAGPEIAVASTKAYTAQIAVLAVLASVAADKNGINIGFDLVKELGIAANAMEALCDQKDEMEMIAREYLTVSRNAFFIGRGLDYFVCVEGALKLKEISYIQAEGFAGGELKHGTIALIEQGTPVFALATQEHVNLSIRGNVKEVAARGANTCIISLKGLDDADDRFVLPEVNPALAPLVSVVPLQLIAYYAALHRGCDVDKPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSUG_STAAW
Sequence: MANLQKYIEYSREVQQALENNQPIVALESTIISHGMPYPQNVEMATTVEQIIRNNGAIPATIAIIDGKIKIGLESEDLEILATSKDVAKVSRRDLAEVVAMKCVGATTVATTMICAAMAGIQFFVTGGIGGVHKGAEHTMDISADLEELSKTNVTVICAGAKSILDLPKTMEYLETKGVPVIGYQTNELPAFFTRESGVKLTSSVETPERLADIHLTKQQLNLEGGIVVANPIPYEHALSKAYIEAIINEAVVEAENQGIKGKDATPFLLGKIVEKTNGKSLAANIKLVENNAALGAKIAVAVNKLL
What is the function of this protein?
Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil.  Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
What are the official names of this protein?
Pseudouridine-5'-phosphate glycosidase, PsiMP glycosidase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine-5'-phosphate glycosidase family.
Protein: KHSE_SERP5
Sequence: MVKVYAPASIGNVSVGFDVLGAAVSPIDGTLLGDCVSVEAAETFSLQNAGRFVSKLPDDPKENIVYQCWERFCQEIGQQIPVAMRLEKNMPIGSGLGSSACSVVAGLMAMNEFCNRPLDKMTLLGLMGELEGRISGSVHYDNVAPCYLGGLQLMLEEEGFISQEVPCFKDWLWVMAYPGIKVSTAEARAILPAQYRRQDCISHGRYLAGFIHACHTQQPRLAAKLMQDVIAEPYRTRLLPGFADARKAAQDIGALACGISGSGPTLFAVCDDGATAQRMADWLTNHYLQNDEGFVHICRLDTAGARLLG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_TRYBB
Sequence: MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPEFVDIIKATQ
What are the official names of this protein?
Triosephosphate isomerase, glycosomal, TIM, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Glycosome.
Protein: AZO1_STAEQ
Sequence: MKGLIIIGSAQVGSHTNALSKYLKGQLGEHDVEVEIFDLAEKPIHQLDFAGTTQAVDEIKNNVKSLQSKAMEADFLILGTPNYHGSFSGILKNALDHLNMDHFKMKPVGLICNSGGIVSSEPLSHLRVIVRSLLGIAVPTQIATHDSDYAKLEDGTLYLEDNEFQLRAKLFVDQIVSFVTNSPYEHLK
What is the function of this protein?
Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines.  Requires NADPH, but not NADH, as an electron donor for its activity (By similarity).
What are the official names of this protein?
FMN-dependent NADPH-azoreductase, NADPH-dependent flavo-azoreductase, NADPH-flavin azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 2 family.
Protein: PAT_SALTI
Sequence: MNRLPSSASALACSAHALNLIEKRTLNHEEMKALNREVIDYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAGSLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRRPFMPLLPGFRHVPFGNIDAMSMAFSEGKKTGDEIAAVILEPIQGEGGVILPPQGYLTEVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQAEQKGDTLLDGFRQLAREYPNLVHEARGKGMLMAIEFVDNETGYRFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIELCEQVLKSARNALAAMQVSVEEV
What is the function of this protein?
Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline.  This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4-aminobutanal.  Also functions as a cadaverine transaminase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Putrescine aminotransferase, PAT, PATase, Cadaverine transaminase, Diamine transaminase, Putrescine transaminase, Putrescine--2-oxoglutaric acid transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Putrescine aminotransferase subfamily.
Protein: LEU3_NEIG1
Sequence: MTKHIAILRGDGIGPEIVAETVRVLDKFIAQGLDADYEYAPLGGEAYDEYGHPYPEFTQNLCRKADAVLLGAVGSPQYDNLDRPLRPERGLLAIRKDLNLFANLRPAVLYPELANASTLKPEIVAGLDILIVRELTGDIYFGEPRGIRVLENGEHEGYNTMKYSESEIRRIAHVAFQSAQKRSKKVCSVGKANVLETTELWREIFEEIGKQYPDVELSHMYVDNAAMQLVRAPKQFDVIATGNIFGDILSDEASMLTGSIGMLPSASLDENGKGLYEPSHGSAPDIAGQNKANPLATILSLAMLLRYSLNDEARAQQVENSVQKVLQQGLRTGDIYEEGTKLVSCSEMGDAVLAAL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_METNO
Sequence: MIIGIGSDLCDIRRITRSLERFGDRFTHRVFTEGERARSDRRAARAPSYARRFAAKEACAKALGTGMAQGVFWRDMEVVNLPSGRPTLRLTGGAAAQLAAITPAGHRALVHVTLTDDPPLAQAFVVIEALPE
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTB2_STRMU
Sequence: MTEYNWNERHIITFPEEILALSTKDLHVYYGEKEAIKGIDMQFKKKKITALIGPSGCGKSTFLRSLNRMNDTIDIAKVTGQILFEGIDVNAANINVYEMRKHIGMVFQRPNPFAKSIYKNITFAYERAGVKDKQFLDDIVETSLKQAALWEQVKDDLHKSAFTLSGGQQQRLCIARAIAVKPDILLMDEPASALDPIATMQLEETMSELKENYTIIIVTHNMQQAARASDYTAFFYLGDLIEYDKTNNIFQNAKLQSTSDYVSGHFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 2, ABC phosphate transporter 2, Phosphate-transporting ATPase 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TRHO_CORGL
Sequence: MATSKILLYYAFTPLSDPKAVQLWQRELCESLNLRGRILISTHGINGTVGGDIDDCKAYIKKTREYPGFNRMQFKWSEGGAEDFPKLSVKVRDEIVAFGAPDELKVDENGVVGGGVHLKPQQVNELVEARGDEVVFFDGRNAMEAQIGKFKDAVVPDVETTHDFIAEIESGKYDDLKDKPVVTYCTGGIRCEILSSLMINRGFKEVYQIDGGIVRYGEQFGNKGLWEGSLYVFDKRMHMEFGEDYKEVGHCIHCDTPTNKFEHCLNEDDCRELVLMCPDCFANVETRHCKRERCAAIAADFAEQGIDPLVTS
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: MENF_BACSU
Sequence: MVTTVQRTFRKEVLHALHKAKEVNHAVLISYSRQIESLDPLSFFNYGAKKYTGNRFFWSDPESELTIVGLGKEAVFQTNQKNSERYREVFEQWERFKKTAFHIYEEEKLQHSAVGPVLFGGFSFDPCEERGSQWDHFSEGDFFVPALMLTMTAEGPFLTVNRWVSGGEDAEAVLEGLKAFAAEFMVPDFKQEDQAVIAAAEELDKDDWLKAIETATSQIKEKQYDKVVLARELLLTFDGPIQIEPVLKTLLDDQQTSYVFAIEQEGKTFVGASPERLIKRDGGTVMSSCLAGSIKRGVNEEDDRRIGLELLNDEKNLLEHDIVVGMIHNAFVSSCSEVEKPDGPVLYKTKSVQHLFTPIVGQLRESASIFDLIEKLHPTPALGGSPQEKAVDVIREIEPMSRGWYAAPIGWIDSQDNGEFAVAIRSGLIEGSTARLFAGCGIVEDSEPISEYEETQIKLKPMISALGGERR
What is the function of this protein?
Catalyzes the conversion of chorismate to isochorismate.
What are the official names of this protein?
Isochorismate synthase MenF, Isochorismate mutase.
What is the protein family that this protein belongs to?
Belongs to the isochorismate synthase family.
Protein: RL362_SACEN
Sequence: MKVQPSVKRICDKCQVIRRHGRVLVICDNQRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.