PharMolix/UniProtQA huggingface dataset:
Protein: SYFA_BACAC
Sequence: MEARLKELKQKALELIEEAKELKGLNDVRVAYLGKKGPITEVLRGMGKLSAEERPRMGALVNEVREAIQTRLDDKISNLEKAVIEAKLATETIDVTLPGRPVETGCHHPLTAVVEQIEDVFIGMGYEVAEGTEVEKDYYNFEALNLPKDHPARDMQDTFYITEETLLRTHTSSVQARTMENNKEKGPIKIICPGKVYRRDDDDATHSHQFMQIEGLVIDKNIRMSDLKGTLQVFVKKMFGEDREIRLRPSFFPFTEPSVEMDISCMMCHGKGCGTCKGTGWIEILGAGMVHPNVLEMAGYDSKEYQGFAFGMGAERIAMLKYGVDDIRHFYTNDVRFLQQFKRA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR9_OLTVI
Sequence: MGTGRRKRAVAQVKLVAGEGKLIINGKPGFDYLHNNATAILSIQGPFQLFKLQKKFDTIVKVHGGGLSAQADAIKLGVARALCEINTSHRPVLKSNGYLTRDARIVERKKAGLKKARKAPQFSKR
What are the official names of this protein?
30S ribosomal protein S9, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EXT1_CAEEL
Sequence: MQNVMKFHLVIFMLFGSVRLQNPTIERKQCTMSNCFDFSKCSTSKKVYIHPMEKRFEESPQSVIYSKILKHFLESNHYTNDPNEACIFLLGIDTTDRDVRSQNYVKNVNDYIESLDPSVWNNGRNHLIFNFYHGTFPDYDDHNLNFDTGEAMIARASSSENNFIKVFDVSLPLFHENHPYEIKESKSERNDDRIENQRKYLVSFKGKRYVYGIGSGTRNLVHHLHNGDDIVMVTTCKHNNDWQVYQDDRCQRDNDEYDRWEYDELLANSTFCLVPRGRRLGSFRFLETLRSGCVPVVISDSWILPFSETIDWNSAAIVVAERDALSIPELLMSTSRRRVKELRESARNVYDAYLRSIQVISDHVLRIIFKRIDNKIELEDHQ
What is the function of this protein?
Required for the biosynthesis of heparan sulfate by positively regulating N-acetylglucosamine transferase II (GlcNAcT-II) and glucuronyl transferase II (GlcAT-II) activities of glycosyltransferase rib-2 (PubMed:17237233).  Probably not directly involved in chondroitin sulfate biosynthesis but negatively regulates chondroitin sulfate levels (PubMed:16828468, PubMed:17237233).  Maternally required for normal ventral epidermal enclosure and for embryo elongation during the early stages of embryonic development (PubMed:17237233).  In addition, involved in the elongation of the pharyngeal isthmus and in the organization of the actin cytoskeleton in the pharyngeal muscles during the later stages embryonic development (PubMed:16828468).  In adults, regulates egg-laying and the normal morphogenesis of the vulva (PubMed:17237233).  Also involved in the directed migration of hermaphrodite-specific neurons (PubMed:17237233, PubMed:24052309).
What are the official names of this protein?
Exostosin-1 homolog, Multiple exostoses homolog 1, Related to mammalian RIB protein 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 47 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Golgi apparatus.
Protein: AFTC_MYCTO
Sequence: MYGALVTAADSIRTGLGASLLAGFRPRTGAPSTATILRSALWPAAVLSVLHRSIVLTTNGNITDDFKPVYRAVLNFRRGWDIYNEHFDYVDPHYLYPPGGTLLMAPFGYLPFAPSRYLFISINTAAILVAAYLLLRMFNFTLTSVAAPALILAMFATETVTNTLVFTNINGCILLLEVLFLRWLLDGRASRQWCGGLAIGLTLVLKPLLGPLLLLPLLNRQWRALVAAVVVPVVVNVAALPLVSDPMSFFTRTLPYILGTRDYFNSSILGNGVYFGLPTWLILFLRILFTAITFGALWLLYRYYRTGDPLFWFTTSSGVLLLWSWLVMSLAQGYYSMMLFPFLMTVVLPNSVIRNWPAWLGVYGFMTLDRWLLFNWMRWGRALEYLKITYGWSLLLIVTFTVLYFRYLDAKADNRLDGGIDPAWLTPEREGQR
What is the function of this protein?
Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall.  Catalyzes the addition of an arabinofuranosyl (Araf) residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) on the C-3 of an alpha-(1->5)-linked Araf from the arabinan backbone of AG.
What are the official names of this protein?
Alpha-(1->3)-arabinofuranosyltransferase, Arabinofuranan 3-O-arabinosyltransferase, Arabinofuranosyltransferase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 87 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYRH_DESRM
Sequence: MVTPKFRRVILKLSGEALAGQKGYGIDPEVVYSIASQIKDVLEHRVQLAIVVGGGNIWRGISGSTKGMDRATADYMGMLATVINSLALQDALEKIEVDTRVQTSFEMRAVAETYIRRRAIRHMEKGRVVIFAAGTGNPYFSTDTTAALRAAEVEAEIILMAKQVDGVYDADPLKHPGAKRFDELTYIDVLNRGLQVMDSTAVSLCMDNKIPLLVFDLNTEGNIKRAILGERIGTFVGGDLNG
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H32_MUSPA
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.2.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: 3SX2_OPHHA
Sequence: MKNLLLTFLVVTIVCLDLGYTLICNRVHGLQTCEPAHKFCFSKTVMPFPNHPLTLMGCTYSCPTERNAVCCSTDKCN
What is the function of this protein?
This three-finger toxin binds and inhibits the nicotinic acetylcholine receptor (nAChR).
What are the official names of this protein?
Short neurotoxin OH-32, Three-finger toxin, 3FTx.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GLND_ECOL5
Sequence: MNTLPEQYANTALPTLHGQPQNPCAWPRDELTVGGIKAHIDTFQRWLGDAFDNGISAEQLIEARTEFIDQLLQRLWIEAGFSQIADLALVAVGGYGRGELHPLSDIDLLILSRKKLPDDQAQKVGELLTLLWDVKLEVGHSVRTLEECMLEGLSDLTVATNLIESRLLIGDVALFLELQKHIFSEGFWPSDKFYAAKVEEQNQRHQRYHGTSYNLEPDIKSSPGGLRDIHTLQWVARRHFGATSLDEMVGFGFLTSAERAELNECLHILWRIRFALHLVVSRYDNRLLFDRQLSVAQRLNYSGEGNEPVERMMKDYFRVTRRVSELNQMLLQLFDEAILALPADEKPRPIDDEFQLRGTLIDLRDETLFMRQPEAILRMFYTMVRNSAITGIYSTTLRQLRHARRHLQQPLCNIPEARKLFLSILRHPGAVRRGLLPMHRHSVLGAYMPQWSHIVGQMQFDLFHAYTVDEHTIRVMLKLESFASEETRQRHPLCVDVWPRLPSTELIFIAALFHDIAKGRGGDHSILGAQDVVHFAELHGLNSRETQLVAWLVRQHLLMSVTAQRRDIQDPEVIKQFAEEVQTENRLRYLVCLTVADICATNETLWNSWKQSLLRELYFATEKQLRRGMQNTPDMRERVRHHQLQALALLRMDNIDEEALHQIWSRCRANYFVRHSPNQLAWHARHLLQHDLSKPLVLLSPQATRGGTEIFIWSPDRPYLFAAVCAELDRRNLSVHDAQIFTTRDGMAMDTFIVLEPDGSPLSADRHEVIRFGLEQVLTQSSWQPPQPRRQPAKLRHFTVETEVTFLPTHTDRKSFLELIALDQPGLLARVGKIFADLGISLHGARITTIGERVEDLFIIATADRRALNNELQQEVHQRLTEALNPNDKG
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: THID_SYNE7
Sequence: MAVPIALTIAGSDSGGGAGIQADLRTFAFHQVHGTCAITCVTAQNTLGVTRVDAIAPAGVAAQLDAVLSDLPPQALKTGMLLNAEIMEVVAGTIAPLFIPRIIDPVMVSRTGAVLIDQAAIAVLRDHLLPLATVLTPNRYEAQLLAGMDIQDAADLDRAARIIRDLGPQAVLIKGGAATGDWHGVDWWWDGQQSHILKTEAIATPHTHGSGCTLAAAIAANAALGLEILAAAQAAKHYVTKALRHSLAIGQGQGPLGHFYPLF
What is the function of this protein?
Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.
What are the official names of this protein?
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase, Hydroxymethylpyrimidine kinase, HMP kinase, Hydroxymethylpyrimidine phosphate kinase, HMP-P kinase, HMP-phosphate kinase, HMPP kinase.
What is the protein family that this protein belongs to?
Belongs to the ThiD family.
Protein: ATF3_DROME
Sequence: MFNSNIPASSLLSIDSGGLLMGGHTPKTPEILNSLIAMTNPLENFSYSSAAAAAAAVSVASSSASCSAASTPVVTVRHFNGHPNGQSHSQDSSHSSCSGSPLDSPAGTATTPSVQQTCSRLIKEGLKLSIQSKRKLSTCDSSSGSEQPHSKYSRRSSNHNGHSGSSNNYSGSMSNANDLDDDCEESSDDDSETKSQPKGLTPEDEDRRRRRRERNKIAATKCRMKKRERTQNLIKESEVLDTQNVELKNQVRQLETERQKLVDMLKSHGCQRAGGCQLPSQLLQSPAQKYLSELELETVSIDGPNSGNNNQRLQSIPSMATFKYGSKTAAAMAQQLPNGYCKPSPSAQEFEHAGYQQQQQQQQQQQPQSLNPAGNNVIDQQHANPSPSLLSDYVPNCDGLTGSASNHPSHNNNNNNNNSSGASSNTSNNNSNISSHSSNATSSTTPTATSSAIEFVKNELVDSQSPYTTALSAERFLFEPSDGFPDIKHACVLPSPCGINGLNMASVVNTNGSTGNNNNSHHNNNNNNNNHLMDFHQGLQHGNIGTGVGVGVGVGVGVGVGVGVMTPYDDEQLLLLKNGCFATDLLSQLVEEGGEYVDLDSATAFMNNGSCLA
What is the function of this protein?
Transcription factor which binds to the cAMP response element (CRE) (PubMed:20023169).  Regulates metabolic and innate immune homeostasis, possibly by controlling appropriate expression of genes involved in peritrophic matrix composition and ensuring the normal digestive and immune function of the gut (PubMed:22851689).  Required for the expression of odorant receptors Or43b and Or47b (PubMed:26848073).
What are the official names of this protein?
Activating transcription factor 3.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. ATF subfamily.
Protein: ECEL1_HUMAN
Sequence: MEPPYSLTAHYDEFQEVKYVSRCGAGGARGASLPPGFPLGAARSATGARSGLPRWNRREVCLLSGLVFAAGLCAILAAMLALKYLGPVAAGGGACPEGCPERKAFARAARFLAANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTYGTIAAIGEQNEERLRRLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGGWDLGGAEERPGVAARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDGLTLPERTLYLAQDEDSEKILAAYRVFMERVLSLLGADAVEQKAQEILQVEQQLANITVSEHDDLRRDVSSMYNKVTLGQLQKITPHLRWKWLLDQIFQEDFSEEEEVVLLATDYMQQVSQLIRSTPHRVLHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKPQELARVCLGQANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAETRAAARAKLQYMMVMVGYPDFLLKPDAVDKEYEFEVHEKTYFKNILNSIRFSIQLSVKKIRQEVDKSTWLLPPQALNAYYLPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDDWGGQYDRSGNLLHWWTEASYSRFLRKAECIVRLYDNFTVYNQRVNGKHTLGENIADMGGLKLAYHAYQKWVREHGPEHPLPRLKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVLGSVSQFEEFGRAFHCPKDSPMNPAHKCSVW
What is the function of this protein?
May contribute to the degradation of peptide hormones and be involved in the inactivation of neuronal peptides.
What are the official names of this protein?
Endothelin-converting enzyme-like 1, Xce protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase M13 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: PYRH_NITMU
Sequence: MTIPAYKRILLKLSGEALMGDDSYGINRDVIERIVAEIAEVNQLGVEVAVVIGGGNIFRGMTSSAEGMDRATADYMGMLATVMNALALQDAMRRAGLVSRVQSALRIDQVVEPYIRGKAIRYLEEGKIVIFAAGTGNPFFTTDTAAALRGMEMNVDIVLKATKVDGVYTTDPKINPDAERYQRLSFDTAIAENLKVMDATALTLCRDQKLPLKVFSIFKAEALRRVVMGEEEGTLVEV
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GBP2_HUMAN
Sequence: MAPEINLPGPMSLIDNTKGQLVVNPEALKILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKKNGFSLGSTVKSHTKGIWMWCVPHPKKPEHTLVLLDTEGLGDIEKGDNENDSWIFALAILLSSTFVYNSMGTINQQAMDQLHYVTELTDRIKANSSPGNNSVDDSADFVSFFPAFVWTLRDFTLELEVDGEPITADDYLELSLKLRKGTDKKSKSFNDPRLCIRKFFPKRKCFVFDWPAPKKYLAHLEQLKEEELNPDFIEQVAEFCSYILSHSNVKTLSGGIPVNGPRLESLVLTYVNAISSGDLPCMENAVLALAQIENSAAVEKAIAHYEQQMGQKVQLPTETLQELLDLHRDSEREAIEVFMKNSFKDVDQMFQRKLGAQLEARRDDFCKQNSKASSDCCMALLQDIFGPLEEDVKQGTFSKPGGYRLFTQKLQELKNKYYQVPRKGIQAKEVLKKYLESKEDVADALLQTDQSLSEKEKAIEVERIKAESAEAAKKMLEEIQKKNEEMMEQKEKSYQEHVKQLTEKMERDRAQLMAEQEKTLALKLQEQERLLKEGFENESKRLQKDIWDIQMRSKSLEPICNIL
What is the function of this protein?
Interferon (IFN)-inducible GTPase that plays important roles in innate immunity against a diverse range of bacterial, viral and protozoan pathogens (PubMed:31091448).  Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions, but the major reaction product is GDP (PubMed:8706832).  Following infection, recruited to the pathogen-containing vacuoles or vacuole-escaped bacteria and acts as a positive regulator of inflammasome assembly by promoting the release of inflammasome ligands from bacteria (By similarity).  Acts by promoting lysis of pathogen-containing vacuoles, releasing pathogens into the cytosol (By similarity).  Following pathogen release in the cytosol, promotes recruitment of proteins that mediate bacterial cytolysis: this liberates ligands that are detected by inflammasomes, such as lipopolysaccharide (LPS) that activates the non-canonical CASP4/CASP11 inflammasome or double-stranded DNA (dsDNA) that activates the AIM2 inflammasome (By similarity).  Confers protection to the protozoan pathogen Toxoplasma gondii (By similarity).  Independently of its GTPase activity, acts as an inhibitor of various viruses infectivity, such as HIV-1, Zika and influenza A viruses, by inhibiting FURIN-mediated maturation of viral envelope proteins (PubMed:31091448).
What are the official names of this protein?
Guanylate-binding protein 2, GTP-binding protein 2, GBP-2, HuGBP-2, Guanine nucleotide-binding protein 2, Interferon-induced guanylate-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. GB1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus membrane. Membrane; Lipid- anchor. Cytoplasmic vesicle. Note=GBP2-GBP5 dimers localize to the Golgi apparatus.
Protein: PDXJ_PSEPK
Sequence: MTHSNRMLLGVNIDHVATLRQARGTRYPDPVKAALDAEEAGADGITVHLREDRRHIQERDVVLLKDVLQTRMNFEMGVTEEMMAFAEKIRPAHICLVPETRQELTTEGGLDVAGQEARIKAAVERLARTGAEVSLFIDADERQIEASRRVGAPAIELHTGRYADAETPTEVAEELKRIVEGVAFGVGHGLIVNAGHGLHYHNVEAVAAIKGINELNIGHALVAHALFVGFKAAVAEMKALIVAASR
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_STRPM
Sequence: MSKKRLHEIAKEIGKSSKEVVEHAKYLGLDVKSHASSVEEADAKKIISSFSKASKPDVTASQTVKPKEVAQPSVTVVKETGSEHVEKTQVSKPKSRNFKAEREARAKEQAARKQANGSSHRSQERRGGYRQPNNHQTNEQGDKRITHRSQGDTNDKRIERKASNVSPRHDNHQLVGDRNRSFAKENHKNGRFTNQKKQGRQEPQSKSPKIDFKARAAALKAEQNAEYSRQSETRFRAQQEAKRLAELARQEAKEAALKAQAEEMSHREAALKSIEEAETKLKSSNISAKSTADNRRKKQARPEKNRELTHHSQEGQKKNKKSWNSQNQVRNQKNSNWNKNKKTKKGKNVKNTNTAPKPVTERKFHELPKEFEYTEGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDDADIERFFEDENYLNPENIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKITFLDTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAINKIDKPGANPERVIAELAEYGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEELKADPTVRAIGTVIEARLDKGKGAIATLLVQQGTLHVQDPIVVGNTFGRVRAMVNDLGRRVKSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERSKRALLKQRQNTQRVSLDNLFDTLKAGEIKTVNVIIKADVQGSVEALAASLVKIEVEGVRVNVVHSAVGAINESDVTLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDPVYQEKILGEAIIRETFKVSKVGTIGGFMVINGKVTRDSSVRVIRDSVVIFDGKLASLKHYKDDVKEVGNAQEGGLMIENFNDLKVDDTIEAYIMEEIVRK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLDE_GRABC
Sequence: MDFSSTRVLCIGDVMLDRFMHGSVERISPEAPVPVLRITSTHSMLGGAGNVAHNIADLGGTAILVGLIGHDDTAIALRTHLERVPGIVNALVESPHRPTICKTRFLAAQQQVVRTDDESHLPTQPAEEMLLQTMVATHITECGAVILSDYGKGVLSPAVIKHVIGLARQAGIPVFVDPKRLDFSVYAGATCITPNVKELSAAAHQRADDEASVIAAARIVMQQAEGASILATRSEKGMMLIEAPAEGRDDIAIHTVPARAREVFDVSGAGDTVIATLALAHASGLTLESAMRISNAAAGVVVSKAGTATLNVDELRAELDESAISNGSTGSARSLGEARSLVKKWKQLGLTVGFTNGCFDILHAGHVSLLNEARTRCDRLIVAVNTDASVSRLKGPTRPINGFEDRCTVLAGLRSVDCVVGFQEDTPLSVISVLLPDRLFKGADYREEDVVGGDVVRAAGGKVELIDLVPGRSTTGIVKKISTLT
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: Y135_HELPY
Sequence: MRISLLAVILALLFVACHETKKQILQNEADSTPSEKTIWQPEQK
What are the official names of this protein?
Uncharacterized protein HP_0135.
Protein: MACIR_HUMAN
Sequence: MEVDINGESRSTLTTLPFPGAEANSPGKAEAEKPRCSSTPCSPMRRTVSGYQILHMDSNYLVGFTTGEELLKLAQKCTGGEESKAEAMPSLRSKQLDAGLARSSRLYKTRSRYYQPYEIPAVNGRRRRRMPSSGDKCTKSLPYEPYKALHGPLPLCLLKGKRAHSKSLDYLNLDKMIKEPADTEVLQYQLQHLTLRGDRVFARNNT
What is the function of this protein?
Regulates the macrophage function, by enhancing the resolution of inflammation and wound repair functions mediated by M2 macrophages (PubMed:30659109).  The regulation of macrophage function is, due at least in part, to its ability to inhibit glycolysis (PubMed:30659109).  May also play a role in trafficking of proteins via its interaction with UNC119 and UNC119B cargo adapters: may help the release of UNC119 and UNC119B cargo or the recycling of UNC119 and UNC119B (PubMed:22085962).  May play a role in ciliary membrane localization via its interaction with UNC119B and protein transport into photoreceptor cells (PubMed:22085962).
What are the official names of this protein?
Macrophage immunometabolism regulator.
What is the protein family that this protein belongs to?
Belongs to the UNC119-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, cilium. Note=Localizes to the transition zone and proximal cilium in addition to being found throughout the cytoplasm.
Protein: SERC_SHEFN
Sequence: MSAIYNFCAGPAMLPQAVMQKAQQELVDWNGLGVSVMEISHRSKEFIALTDQAEVTLRKLMSIPANYHVLFMHGGGRAQFSNVVNNFLGDNGQALYLVSGQWSSAAVTEAKKLVSEHNIDSINIVEQINGLYQVKLPDLTAIDKDYRYVHYCSNETVDGIEIFEELDSPWPIVADLSSTIMSHEIDVSKYGLIYAGAQKNIGPSGLSIVIVRDDMLKLPSLPQSSVMDYRVAVEHGSMFNTPPTFAWYLASEVFAWLAAKGGVSAMAEVNQQKAALLYDCIDSNPFYKNGVAPHNRSRMNVTFQLVNDALDSEFLAQAEQAGLVALKGHRIVGGMRASIYNAMPLAGVQALVDFMNNFAVKHS
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TP1_PELRI
Sequence: FLSGLVGALAKMF
What are the official names of this protein?
Temporin-1R.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Temporin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NEF_HV1B9
Sequence: MGGKWSKRRAEGWQTIRERMRRAEPAEPAADGVGAVSRDLARHGAITSSNTNNADIAWLEAQEEGEVGFPVRPQVPLRPMTYKAAVDLSHFLKEKGGLEGLVHSQKRQDILDLWVYHTQGFFPDWQNYTPGPGIRYPLTFGWCYKLVPVEPDEGENNREDNSLLHPANQHGVEDSERQVLVWRFDSRLAFHHVARELHPEYFKN
What is the function of this protein?
Extracellular Nef protein targets CD4(+) T-lymphocytes for apoptosis by interacting with CXCR4 surface receptors.
What are the official names of this protein?
Protein Nef, 3'ORF, Negative factor, F-protein.
What is the protein family that this protein belongs to?
Belongs to the lentivirus primate group Nef protein family.
What are the subcellular locations of this protein?
Host cell membrane; Lipid-anchor; Cytoplasmic side. Virion. Secreted. Host Golgi apparatus membrane. Note=TGN localization requires PACS1. Associates with the inner plasma membrane through its N-terminal domain. Nef stimulates its own export via the release of exosomes. Incorporated in virions at a rate of about 10 molecules per virion, where it is cleaved.
Protein: NM111_COCIM
Sequence: MELNGSPQKPKRKHSGDPHSLPSAKHLRPDSAAPSSPRISGDQTSGDLAVYGYRNVDSADAAAMQMKLPAVQTDSAEWQETIETVVKSVVSIHFCQTASFDTDLSMSSQATGFVVDAKRGYILTNRHVVCAGPFWGYCIFDNHEECDVTPIYRDPVHDFGILKFDPKAIKYMPLTELKLQPESARVGVEIRVVGNDAGEKLSILSGVISRLDRNAPEYGEGYSDFNTNYIQAAAAASGGSSGSPVVNIDGHVIALQAGGRADGAATDYFLPLDRPLRALQCIQKGELVSRGTIQTQWIIKPFDECRRLGLSPEWEAEVRRVAPKETGMLVAEIVLPEGPGDGKLQEGDVLIKANGELLTQFVRLDDILDSSVGGDVHLLVQRGGEDLEVTCKVQDLHAITPSRYVTVAGATFHDLSYQQARLYAIACKGVYVCEAAGSFKLESTFSGWIIDSVDKRPTRNLDEFIEVLKTIPDRARIVLSYRHIRDLHTRGTSIVHIDRHWHPHMRLAQRNDQTGLWDFTDLADPIPAEPPVPRKADFIQLDGVSHPAAADIVRSFVRVSCTMPVKLDGFPQARKTGFGLVVDAEKGLVVISRAIVPFDLCDINITVADSIIVSAKVVFLHPLQNYTIIQYDPSLVQAPVKTARLSPEYIKQGAETLFVGFNQNFRIVVAKTAVTDITTVAIPPNAAAPRYRAINLDAITVDTGLSSQCTSGVLLGEDGVIQALWLNYLGERTQSSHKDVEYHLGLATPSLIPVISQIQSGVIPRLRILDMETYVIQMSQARVMGVSEEWIEKVAKANAARHELFMVRKVDCASPLSADVRPLEEGDIILTLNDKLITRVSEFDMMYDQETLDALIVRNGEEMKIKIKTVPTEDLETDRALIFCGAVLQKPHHAVRQQISKLHSEVYVSARSRGSPAYQYGLSPTNFITAVNGVKTPDLDSFIREVSNIPNNTYFRLRAVTFDNVPWVVTMKKNDHYFPMSEYIKEPSAPLGWRTVNYDRGKERRGTGDIANLNADAMDEGRDEGVSDVEPDIE
What is the function of this protein?
Nuclear serine protease which mediates apoptosis.
What are the official names of this protein?
Pro-apoptotic serine protease NMA111.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MET23_DICDI
Sequence: MKSFIFRQNPRKQQQEQNNLVDYSDSDDDEECNDDIFVNNEIIINVSEKSSKDYGLFIWDGSLVLSWYLFTLTKNNPQFWNGKNVLELNAGVALPSILLSKLGVNKIIITDRIDGFIEIQNNIIDNLNLNGFNINNNNNINDNKIFIEPLSWGNFEKFSNQLTSSSIDYLITSDCFYDNTKNYDDIFATWYYFLLKNDKLVILLTYQVRCNEKTIFNYLKKWKLKSEILSIKDISIPNYNIDSEIILIKITKNQ
What is the function of this protein?
Probable methyltransferase.
What are the official names of this protein?
Methyltransferase-like protein 23.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL23 family.
Protein: LYSM2_BOVIN
Sequence: MADSSPAPSLRAGGPREPRPSAPSPPPPHSRLGSEAEEAELSLSLARTKTRSYGSTASVRAPLGAGVIERHVEHRVRAGDTLQGIALKYGVSMEQIKRANKLFTNDCIFLKKTLNIPVISEKPLLFNGLNSVDSPENETVDSFSHEEELVAAGEDVSPLSPQELDVQPMQPEEVSARDFLQRLDLQIKLSTQAAKKLKGESRDEEGLYTASLYHS
What are the official names of this protein?
LysM and putative peptidoglycan-binding domain-containing protein 2.