PharMolix/UniProtQA huggingface dataset:
Protein: TRPA_LEGPA
Sequence: MNRIDKTLEKLKANRKKMLSPYITAGDPYPELTVSLMHQLVKSGADVLELGIPFSDPMAEGPVIQRAMERALAHSIHCDDVLNMVRQFRKTDTETPVILMGYLNPIEQYGYDLFAQQAVEAGADGTILVDLPPEEADGVSRVWQKHGLYSIYLCSPTTSAERMNFINQHANGYLYYVSLKGVTGSDALKLPELKAQYLQRKAQSKLPLMVGFGIKTPEMAAQVAEFADGVIVGAALINEIIEAYEAKKDPLQASGALLSSMRQAIDNIGSMV
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RS5_METS4
Sequence: MAREREGRRRDEREERDTEFVDRLVHINRVAKVVKGGRRFGFAALVVVGDQKGRVGFGHGKAREVPEAIRKATEAAKRGLIRVALREGRTLHHDVAGRHGSGKVILRAAPQGTGIIAGGPMRAVFESVGMQDVVAKSLGSSNPYNLIRATFDALKREDSPRAVAARRGLKVSALQARRRDAEPGSADSADAA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: PYRH_FRATF
Sequence: MSNDSSECSQKLPKLKRILLKLSGESLSADQGFGINVESAQPIINQIKTLTNFGVELALVVGGGNILRGGRANFGNKIRRATADSMGMIATMINALALRDMLISEGVDAEVFSAKGVDGLLKVASAHEFNQELAKGRVLIFAGGTGNPFVTTDTTASLRAVEIGADALLKATTVNGVYDKDPNKYSDAKRFDKVTFSEVVSKELNVMDLGAFTQCRDFSIPIYVFDLTQPNALVDAVLDSKYGTWVTLD
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_BRUA1
Sequence: MRILLTNDDGIHAEGLAVLERIARKLSDDVWVVAPETDQSGLAHSLTLLEPLRLRQIDARHFALRGTPTDCVIMGVRHVLPGAPDLVLSGVNSGANMADDVTYSGTVAGAMEGTLLGVRAIALSQEYEYAGDRRIVPWETAEAHAPELIGRLMEAGWPEGVLLNLNFPNCAPEEVKGVRVTAQGKLSHDARLDERRDGRGFPYFWLHFGRGKAPVADDSDIAAIRSGCISMTPLHLDLTAHKVRAELGAALGVEA
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIK_HUMAN
Sequence: MSEVRPLSRDILMETLLYEQLLEPPTMEVLGMTDSEEDLDPMEDFDSLECMEGSDALALRLACIGDEMDVSLRAPRLAQLSEVAMHSLGLAFIYDQTEDIRDVLRSFMDGFTTLKENIMRFWRSPNPGSWVSCEQVLLALLLLLALLLPLLSGGLHLLLK
What is the function of this protein?
Accelerates programmed cell death.  Association to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity.  Does not interact with BAX.
What are the official names of this protein?
Bcl-2-interacting killer, Apoptosis inducer NBK, BIP1, BP4.
What are the subcellular locations of this protein?
Endomembrane system; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. Note=Around the nuclear envelope, and in cytoplasmic membranes.
Protein: ERPA_BURO1
Sequence: MNAVTETAATTTDMPLPFVFTDAAADKVKQLIDEEGNPDLKLRVFVQGGGCSGFQYGFTFDEEVNEDDTVMNKNGVQLLIDSMSYQYLVGAEIDYKDDLNGAQFVIKNPNATTTCGCGSSFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters.
What are the official names of this protein?
Putative iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: RNC_HAEIN
Sequence: MNHLDRLERKIGYRFNDIALLKQALTHRSAATQHNERLEFLGDSILNFTIAEALYHQFPRCNEGELSRMRATLVREPTLAILARQFELGDYMSLGSGELKNGGFRRESILADCVEAIIGAMSLDQGLAVTTQVIRNWYQQLLAEIKPGDNQKDAKTRLQEYLQGKHLPLPTYEVVNIQGEAHCQIFTVKCKVKSAEKIDRTFVAKGSSRRKAEQAAAEQILKELDIK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABPL_PIG
Sequence: MNFSGKYQVQSQENFEAFMKAVGLPDELIQKGKDIKGTSEIVQNGKHFKLTITTGSKVVQNEFTLGEECEMETLTGEKVKTVVQLEGDNKLVTTFKGIKSVTELNGDIITSTMTLGDIVFKRISKRI
What is the function of this protein?
Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes.  Binds cholesterol.  Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm.  May be involved in intracellular lipid transport.
What are the official names of this protein?
Fatty acid-binding protein, liver, Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, L-FABP.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGAL_THEMA
Sequence: MPYEWENPQLVSEGTEKSHASFIPYLDPFSGEWEYPEEFISLNGNWRFLFAKNPFEVPEDFFSEKFDDSNWDEIEVPSNWEMKGYGKPIYTNVVYPFEPNPPFVPKDDNPTGVYRRWIEIPEDWFKKEIFLHFEGVRSFFYLWVNGKKIGFSKDSCTPAEFRLTDVLRPGKNLITVEVLKWSDGSYLEDQDMWWFAGIYRDVYLYALPKFHIRDVFVRTDLDENYRNGKIFLDVEMRNLGEEEEKDLEVTLITPDGDEKTLVKETVKPEDRVLSFAFDVKDPKKWSAETPHLYVLKLKLGEDEKKVNFGFRKIEIKDGTLLFNGKPLYIKGVNRHEFDPDRGHAVTVERMIQDIKLMKQHNINTVRTSHYPNQTKWYDLCDYFGLYVIDEANIESHGIDWDPEVTLANRWEWEKAHFDRIKRMVERDKNHPSIIFWSLGNEAGDGVNFEKAALWIKKRDNTRLIHYEGTTRRGESYYVDVFSLMYPKMDILLEYASKKREKPFIMCEYAHAMGNSVGNLKDYWDVIEKYPYLHGGCIWDWVDQGIRKKDENGREFWAYGGDFGDTPNDGNFCINGVVLPDRTPEPELYEVKKVYQNVKIRQVSKDTYEVENRYLFTNLEMFDGAWKIRKDGEVIEEKTFKIFAEPGEKRLLKIPLPEMDDSEYFLEISFSLSEDTPWAEKGHVVAWEQFLLKAPAFEKKSISDGVSLREDGKHLTVEAKDTVYVFSKLTGLLEQILHRRKKILKSPVVPNFWRVPTDNDIGNRMPQRLAIWKRASKERKLFKMHWKKEENRVSVHSVFQLPGNSWVYTTYTVFGNGDVLVDLSLIPAEDVPEIPRIGFQFTVPEEFGTVEWYGRGPHETYWDRKESGLFARYRKAVGEMMHRYVRPQETGNRSDVRWFALSDGETKLFVSGMPQIDFSVWPFSMEDLERVQHISELPERDFVTVNVDFRQMGLGGDDSWGAMPHLEYRLLPKPYRFSFRMRISEEIPSWRVLAAIPETLHVEMSSEDVIREGDTLRVKFSLLNDTPLSKEKQVVLFVDGNEYSVRRVVIPPFKKEELVFKVEGLKKGEHLIHTNLNTRKTIYVR
What are the official names of this protein?
Beta-galactosidase, Beta-gal, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
Protein: DPB31_ARATH
Sequence: MVSSKKPKEKKARSDVVVNKASGRSKRSSGSRTKKTSNKVNIVKKKPEIYEISESSSSDSVEEAIRGDEAKKSNGVVSKRGNGKSVGIPTKTSKNREEDDGGAEDAKIKFPMNRIRRIMRSDNSAPQIMQDAVFLVNKATEMFIERFSEEAYDSSVKDKKKFIHYKHLSSVVSNDQRYEFLADSVPEKLKAEAALEEWERGMTDAG
What is the function of this protein?
Transcription factor which promotes the expression of heat stress-inducible genes by contributing to the formation of a heat stress-specific transcriptional complex with NF-Y subunits (e. g.  NF-YA2 and NF-YB3) and DREB2A at the promoter of target genes, thus promoting heat tolerance (PubMed:25490919).  Together with the glyceraldehyde-3-phosphate dehydrogenase (GAPC), enhances heat tolerance (PubMed:32651385).
What are the official names of this protein?
DNA polymerase II subunit B3-1, Nuclear factor Y, subunit C10, AtNF-YC10.
What is the protein family that this protein belongs to?
Belongs to the NFYC/HAP5 subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SET2_ASPFU
Sequence: MSSHDNADSPSSSVANAVTAMKIEQHDGAADMLLSNGGDAVLKRDSNGLSEHAVTAKDYPGMNDLASSTVKSRTSSLTPIKTENGDSTAKEEKVGGDITVKMEPGQPPKLSRSSSQKVVAQPPQLFLHLPDSTAEAQSTFEVMETCTYANKYMGYTEHAMECDCAEEWEPSLSRNLACGEDSDCINRATKIECVGDCSCGAECQNQRFQRKEYANVAVIKTEKKGFGLRAETDLRPHQFIFEYVGEVINEAQFRRRMRQYDEEGIKHFYFMSLSRGEFVDATKKGNLGRFCNHSCNPNCYVDKWVVGEKLRMGIFAERAIQAGEELVFNYNVDRYGADPQPCYCGEPNCTGFIGGKTQTDRATKLSNATIEALGIEDADSWDTVVAKRPRKKKMGEDDEEYVDSVQPKSLDENGVTKVMAALMQCKEKWIAVKLLRRIERCDDDRVRHRVVKMHGYQILNSQLTLWKDDFNVVLQILNILDGFPRLTRNKIIDSKIESTVQPLTTCGDERVEKKAAALLQHWATLEVGYRIPRMKRDPNAVASVSQFGRREHTTDEQKRSQSRSRSRSPSLDAPRGPANPGRKSNGPRNSQHHGARQFRRQFNPLPPGWFAAESHGRTYYYCARGDVTWTRPIHAAPEAEVPGQQAKNKALQGIIDNILNAKENTPKEKTVTPGTPQASRETASLNEGQERWRSYSEEKQKKLYENTLFPHIKYVVDKFKHKLPKEDLKRYAKDVAKKLVNSDFKNNRVEDPTKISEKQQKKVKAFCKEFFDKAVAKHRAYEQRKAEKQAKGGNSKADDMISGHNTVEDDVKLSDGEAEKVEENDNSMSSDPQGILKRKREDEMDIGEGAAEEAMKRQKSSTPIPPPPPPPPPLGDEEQPTPNGTGEDDFLAENGVSMLHSPGSAPTPPPPPPLSTEHSDNDEMGQSPSMSNHLLEQKSFPAPLGEEYEADSGKLSSNRIGIEGQV
What is the function of this protein?
Histone methyltransferase that trimethylates histone H3 'Lys-36' forming H3K36me3.  Involved in transcription elongation as well as in transcription repression.
What are the official names of this protein?
Histone-lysine N-methyltransferase, H3 lysine-36 specific, SET domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: GATA_BARHE
Sequence: MTDLTTLTIAQARDALKKRELKATELTEAYLKAIELANPILNTYVAITAEQAMKMAAKSDSRLAKGHGGILEGIPLGIKDLFATQDVHTQACSYILDGFKPHYESTVTANLWRDGAVMLGKLNMDEFAMGSSNETSYYGPVISPWRKKDSNEKLVPGGSSGGSAAAVAAGLCVGATATDTGGSIRQPAAFTGTVGIKPTYGRCSRWGTIAFASSLDQAGPIGRNVRDCAILLKSMASFDEKDSTSVNLPVPDYESYIGQSIKGMKIGIPKEYYLEGMSPEIVELWQKGINWLKEAGAEIKNISLPHTKYALPAYYIVAPAEASSNLARYDGVRFGLRIPGKDVIEMYENTRSVGFGNEVKRRILIGTYVLSSGYYDAYYLKAQKVRTLVKRDFDQCFSSGVDAILTPATPTPAFGIADEKIKNDTVAMYLNDIFTVPVNMAGLPGISVPSGLSSNGLPLGLQLIGKPFAEEVIFQIAHIIEQAAGMFSAEKWWT
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: THIT_LACLM
Sequence: MSNSKFNVRLLTEIAFMAALAFIISLIPNTVYGWIIVEIACIPILLLSLRRGLTAGLVGGLIWGILSMITGHAYILSLSQAFLEYLVAPVSLGIAGLFRQKTAPLKLAPVLLGTFVAVLLKYFFHFIAGIIFWSQYAWKGWGAVAYSLAVNGISGILTAIAAFVILIIFVKKFPKLFIHSNY
What is the function of this protein?
Probably a thiamine-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.  The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins.
What are the official names of this protein?
Thiamine transporter ThiT, Thiamine ECF transporter S component ThiT.
What is the protein family that this protein belongs to?
Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Thiamine transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOA_CAMJE
Sequence: MRNITTSAYTPTEFTIENISDTVAKISAWPFEIGYGITLAHPLRRLLYTSTIGYAPTAIHIDGVAHEFDSMRGMLEDVALFIINLKKLRFKIKGDSNKEIVEFSFKGSKEIYGKDLNNDQVEVVNKDAYLATINEDAELKFTLIVEKGIGYVPSEEIKELINDPKFIALDAFFTPVREATYDIEKVLFEDNPDYEKVVLTVTTDGQITPNEAFQNALEAMYKQLSVFDKITNVRSVIKNQATSNELENTKLLQNITDLNLSARSYNCLEKAGVVYIGELALMSVSELAGLKNLGKKSLDEIKNIMESIGFPVGTSKLSDNKEILKNKIAELKAQNEG
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: OBG_DEHMB
Sequence: MFDRVEINIKAGDGGSGKVSFRREKFVPYGGPDGGDGGDGGNVYLEADSGLYSLLNFKHKRVHKASNGEGGMGSRCTGHNGADLVIKVPVGTVATILEENGQKRVLADLAADGDRTLVAHGGQGGLGNTHFVSSTNQAPMLAQKGQPGGEYDLILELKLIADVAIIGYPNVGKSSLLSLLTAAKPKVANYPFTTLSPVMGVIERPEGVFVMAEVPGLIENAHLGKGLGHDFLRHISRTRMVIHLLDGTSENPIDDMIKVNSELYLYDASLSERPQVVAINKIDDELVQLRREELKETFKEAGLEVFFISALTGEGVDVLLAKVAEKLDILKAADISETAPDHEVKIFRPAPKGKMGFRITRLEDGWQVEAPEIERIIEHSDIEDPEVRRQVMVLLKHRSVQQSLIKSGAVIGQKIITGRMEWYL
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CXA1_PIG
Sequence: MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPGCENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDGVNVEMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSVFEVAFLLIQWYIYGFSLSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYAFFKGVKDRVKGKSDPYHATTGPLSPSKDCGSPKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRNYNKQASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDNQNSKKLDAGHELQPLAIVDQRPSSRASSRASSRPRPDDLEI
What is the function of this protein?
Gap junction protein that acts as a regulator of bladder capacity.  A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.  May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph.  Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract.  May play a role in cell growth inhibition through the regulation of NOV expression and localization.  Plays an essential role in gap junction communication in the ventricles (By similarity).
What are the official names of this protein?
Gap junction alpha-1 protein, Connexin-43, Cx43.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Alpha-type (group II) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Endoplasmic reticulum. Note=Localizes at the intercalated disk (ICD) in cardiomyocytes and proper localization at ICD is dependent on TMEM65.
Protein: MSCL_LEGPA
Sequence: MSLLKEFKEFAMRGNVIDLAVAVVMGVAFNKIVTALVDGIIMPCVGLLLGGINIAGLSFTVGDAQIKWGSFLQNVIDFIIVAFAIFVLIKLINLLQRKKENEPEPVTPEIQLLTEIRDLLARNSSKI
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNAK2_PHOPR
Sequence: MSKIIGIDLGTTNSCIALLDGDKPRVIENAEGERTTASVIAYTQDGEILVGQPAKRQAVTNPKNTLFAIKRLLGRRFEDEEVQRDIEIMPFNIVKADNGDAWVEAKGKKMAAPQVSAEVLKKMKKTAEDYLGEEVTGAVITVPAYFNDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGLDKQGGERTIAVYDLGGGTFDISIIEIDEVDGEKTFEVLSTNGDTHLGGEDFDNRMINYLVGEFKKEQGIDLKSDPLAMQRVKEAAEKAKIELSSAQQTDVNLPYVTADAAGPKHMNVKVTRAKLESLVEDLVQRTLEPLKIALTDANLSITDITDVILVGGQTRMPMVQAKVTEFFGKEPRKDVNPDEAVAVGAAIQAGVLAGEVKDVLLLDVTPLSLGIETMGGVMTKLIEKNTTIPTKANQVFSTAEDNQSAVTIHVLQGERKQSSYNKSLGQFNLEGIQAGSRGTAQIDVTFDLDADGILHVSATDKATNKEQKITIQASGGLSNDDIEKMVQEAEANKEADKMFEELVTARNQADQLVHSTRKQVEELGDALPADEKAKIDTAIADVETALKGEDKAAIDNATQALMTASQALVQMAQQQAQAQHAQSSQQTNDTTGQSSTDDDVFEAEFEEVKDK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK 2, HSP70 2, Heat shock 70 kDa protein 2, Heat shock protein 70 2.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: UREA_SOYBN
Sequence: MKLSPREIEKLDLHNAGYLAQKRLARGLRLNYVETVALIATQILEFVRDGEKTVAQLMCIGRELLGRKQVLPAVPHLVESVQVEATFRDGTKLVTIHDLFACENGNLELALFGSFLPVPSLDKFTENEEDHRTPGEIICRSENLILNPRRNAIILRVVNKGDRPIQVGSHYHFIEVNPYLTFDRRKAYGMRLNIAAGNATRFEPGECKSVVLVSIGGNKVIRGGNNIADGPVNDSNCRAAMKAVVTRGFGHVEEENAREGVTGEDYSLTTVISREEYAHKYGPTTGDKIRLGDTDLFAEIEKDFAVYGDECVFGGGKVIRDGMGQSSGHPPEGSLDTVITNAVIIDYTGIIKADIGIKDGLIISTGKAGNPDIMNDVFPNMIIGANTEVIAGEGLIVTAGAIDCHVHFICPQLVYDAVTSGITTLVGGGTGPADGTRATTCTPAPNQMKLMLQSTDDMPLNFGFTGKGNSAKPDELHEIIRAGAMGLKLHEDWGTTPAAIDSCLTVADQYDIQVNIHTDTLNESGFVEHTIAAFKGRTIHTYHSEGAGGGHAPDIIKVCGEKNVLPSSTNPTRPYTHNTIDEHLDMLMVCHHLNKNIPEDVAFAESRIRAETIAAEDILHDKGAISIISSDSQAMGRIGEVISRTWQTADKMKSQRGPLQPGEDNDNFRIKRYVAKYTINPAIANGLSQYVGSVEAGKLADLVLWKPSFFGAKPEMVIKGGEVAYANMGDPNASIPTPEPVIMRPMFGAFGKAGSSHSIAFVSKAALDEGVKASYGLNKRVEAVKNVRKLTKRDMKLNDTLPQITVDPETYTVTADGEVLTCTAAKTVPLSRNYFLF
What is the function of this protein?
Catalyzes the conversion of urea to ammonia and carbon dioxide, thus allowing organisms to use exogenous and internally generated urea as a nitrogen source (Probable).  May be involved in plant defense to pathogenic fungi (PubMed:22382992).
What are the official names of this protein?
Urease, Ubiquitous urease, Urea amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
Protein: LV1B1_LYCMC
Sequence: MKILAVVLISVIVLNTANGENYYPQKYTNDYYGCQKQTDAFCDKVCKLHLADSGFCDQSWGLAKACKCVNVSYDNSFFFNALESQCPLLNKSAA
What is the function of this protein?
The monomer edited version, similar to alpha-toxins, may modulate voltage-gated sodium channels (Nav) and may block voltage-gated potassium channels (Kv).
What are the official names of this protein?
Lipolysis-activating peptide 1-beta chain, LVP1-beta, Neurotoxin LmNaTx19.
What is the protein family that this protein belongs to?
Belongs to the long (3 C-C) scorpion toxin superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CYA1_DROME
Sequence: MDHAVKATRGRPLNTLRFENDELECLYQRYTLKLQRFSVLGVVALVFVLCGVMAALSLTFNNAATFHNIFNAIVCGLFAVVLVLLQCSVIKDHHLPTLCYGILLFTASICVVSMPTLGSVFPVDTKEVMAEGVWQIVFVVFLAYAMMPLQIWEAVAFGIALPSVHISLTVYKIFTDALRYLEYNQLIANIVIFIGVNVAGLVVNIMMERAQRRTFLDTRNCIASRLEIQDENEKLERLLLSVLPQHVAMQMKNDILSPVAGQFHRIYIQKHENVSILFADIVGFTVLSSQCSAQELVRLLNELFGRFDQLAHDNHCLRIKILGDCYYCVSGLPEPRKDHAKCAVEMGLDMIDAIATVVEATDVILNMRVGIHTGRVLCGVLGLRKWQFDVWSNDVTLANHMESGGEPGRVHVTRATLDSLSGEYEVEAGHGDERSSYLRDHGVDTFFIVPPPHRRKPLMLNTLGVRSAIGSRRKLSFRNVSNVVMQLLHTIKFSEPVPFSNIATGSFPSAASALGGGVSVGGGGGGGGGGVARGSTCEANSGNVQVSEKGSRKVIRLQKILHATPPPHGMGYGSVVGSGGGVDSGISGGGGCVSGGIAGGGGVQVTVGTNPNSTASTISRIHRHNHKNNKSQSKVADKFKRPFRKRHSVAAHHQPTNRVNRFLSQAINARSVDCDKSEHVDRLTLRFRQSDMEREYHKDFDLGFTTAMGCSLLLLILGAALQVTALPRTLILLLLFLFAFIWVSAILMLLLAVRLKWIIWDISESFSLRMAITIFTVILIYSVGQVNVFTCVSDHPCSGNGTTSFQNDSHRKCSLPQYVSLSAAFAFLSVSVFLRLPIIFKSLLVLGMGTIYGLFIELSHQNIFECYDNRVNASIPLHLISLARIAIFMIAILVHGRLVEGTARLDFLWQLQASQEKKEMDVLQESNKRILHNLLPAHVAAHFLDAQFRNNMELYHQSYAKVGVIFASVPNFNEFYTEMDGSDQGLECLRLLNEIIADFDELLKEDRFRGIDKIKTVGSTYMAVVGLIPEYKIQPNDPNSVRRHMTALIEYVKAMRHSLQEINSHSYNNFMLRVGINIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPGYSQVTQEVVDSLVGSHFEFRCRGTIKVKGKGDMVTYFLCDSGNKSLNGEVRNAMSLPQSLHAPDYYMKVSQFPENRVNTDTYSKKENGHLYAGNGVEEQQLLLQHQHKQHDPLPLPAPPPPVHHHLHQQQQQRLNSKLQKQPIFMANGGLPNIRENGNGHNGEHQQQQQQQQQHQQQQQQQQQHGGFMVATTTPPAAVAVPLQPQHHQLQFQHPHQHPLPSAVSVPVQHQILLHHQLQLQHQPVPSVMLREFNIIENPTSGGRHQQMEQLPPHHGSLDLSGMGMGVGAGVLGSDCFMMPRRDRERTYVPPLNQHGHHPPHHLHSNLNLNQSQHPPSFTSLGYGQCRESEPLLHASSVAPVAKIMPMQHAPKYEPPRYTSPHTMLSQQHQQQQQQQHQHQQPQSQSAQDQQTHPAQDPHPLQRQYAMYSQQPQLPPKPVLRTYMKPLPKLPTDLEESRDMSSTDDLSSRPHSPSMSSSDESYSKTTEGEGEGDEDSPRMVNGGHLHHRNGYHLPAGGLVNPLQWLYPCDIQVDPTSPVVDMAHLHDFELSSTTESQGHHTNSNTTSNTQHKGDSCNSFDFQKAAVGTAAGAAIATKSPFERELQRLLNESSRARCLATATTTAGAISTTDQTASNGSRELSYSLSNGKLSSANGHGVGGSGSGSGSGSGSGSAVGNGSGGSGSSNGNLSGGSGSNSNSGNNNSSHHKTEQQQNMDHEHLAGGKLLGSNSFMIAKHPVGLEAIKEITRNKNPSESSQMQTSDTESCEILHENRNQMHVLAMLEMHTAKELNGSHAHHGQHHQQPQRTHRQRPRSKELQYSHESLDGLDGAVQSQSQQRHQRYHHHHHHQQRQQQQQRYNHVQEQEERDDTEDNLADEEFEDDEVGRDVRQKRLQKSELNHKRSEVATEAGNHHDDEVEEEDDDDDEEEDHRNGGREAAPLTNGSMRGLEANVINDELKYGATHLNHQSMDSNPLESQSEWSDDDCREEATGGAESTGYITDEPGLENISLLNEAGLTDAEGALSDVNSLYNAPDVDDTSVSSRASSRLLSLDSLSGLYDCDLDSKHELAIVNASHKISSKFGQPLSPAQQQHQQQQQQQQQQQQQHHQQQLQQNPQHTQAQSHLAPVQFQSAEELRE
What is the function of this protein?
This is a membrane-bound, calmodulin-sensitive adenylyl cyclase.  Inactivation of this cyclase leads to a learning and memory defect.
What are the official names of this protein?
Ca(2+)/calmodulin-responsive adenylate cyclase, ATP pyrophosphate-lyase, Protein rutabaga.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GCST_PROMH
Sequence: MAKQTPLYDEHVACGARMVDFHGWMMPLHYGSQIDEHHNVRQDAGMFDVSHMTIVDLHGPQVKDFLRYLLANDVAKLTEKGKALYTGMLNASGGVIDDLIVYYFDETFYRLVVNSATREKDLAWITEHAKDYVVDIQVRDDLALIAVQGPHAQEKVQRLLSESHRQIVAAMKPFYGVQLDDLFVATTGYTGEAGYEIAMPKEQAVDYWKKLLAVGVKPAGLGARDTLRLEAGMDLYGQEMDETINPLEANMGWTIAWLPEDRQFIGREALEKLRATGTDKLVGLVMREKGVLRAGSAVHFTDDLGELREGVITSGTFSPTLGFSIALARVPAGIKDSAIVLLRNREIPVEVVKPGFVRSGKALV
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: RS18_CAMLR
Sequence: MAEKRKYSRKYCKYTEAKVDFIDYKDTALLKHALSERFKIMPRRLTGTSKKHQEMVEIAIKRARHVALIPYIVDRKEVVTNPFEGL
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: SYFA_BLOPB
Sequence: MSLDPVKKLVILAKSNIMQSNNMDALEAIRIKFLGKKGYLNQHIKNLNDTSLDIKPKLGAAINQAKEDIYTLLIERKNILQSKNIKNTLITDTLDVTLPGRLSDIGTHHPITSTIKRMKIFFNTLGFSVIHGPEIEDDYFNFDALNIPKYHPSRDEHDTFWFDEKRLLRTHTSGVQIRAMINKTPPIRIISFGRVYRKDYDQHHTPMFHQMEGLIVDSNVNFSYLKKILYDFLYNFFETDIILRFRPSYFPFTEPSAEIDVMKKQETGNWLELLGCGMVHPKILHHVDIDTEKFSGFAFGIGIERLTMLQYNIDDIRVFFKNDLQFLDQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDIA2_HUMAN
Sequence: MSRQLLPVLLLLLLRASCPWGQEQGARSPSEEPPEEEIPKEDGILVLSRHTLGLALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAEGIAEWLRRRVGPSAMRLEDEAAAQALIGGRDLVVIGFFQDLQDEDVATFLALAQDALDMTFGLTDRPRLFQQFGLTKDTVVLFKKFDEGRADFPVDEELGLDLGDLSRFLVTHSMRLVTEFNSQTSAKIFAARILNHLLLFVNQTLAAHRELLAGFGEAAPRFRGQVLFVVVDVAADNEHVLQYFGLKAEAAPTLRLVNLETTKKYAPVDGGPVTAASITAFCHAVLNGQVKPYLLSQEIPPDWDQRPVKTLVGKNFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAELDATANELDAFAVHGFPTLKYFPAGPGRKVIEYKSTRDLETFSKFLDNGGVLPTEEPPEEPAAPFPEPPANSTMGSKEEL
What is the function of this protein?
Acts as an intracellular estrogen-binding protein.  May be involved in modulating cellular levels and biological functions of estrogens in the pancreas.  May act as a chaperone that inhibits aggregation of misfolded proteins.
What are the official names of this protein?
Protein disulfide-isomerase A2, Pancreas-specific protein disulfide isomerase, PDIp.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.