PharMolix/UniProtQA huggingface dataset:
Protein: PFKA_SERP5
Sequence: MIKKIGVLTSGGDSPGMNAAIRGVVRAALSEGLEVFGIYDGYLGLYEDRMEKLDRYSVSDMINRGGTFLGSARFPEFRDDSVRAKAIENLQNRGIDALVVIGGDGSYMGAKRLTEEGFPCIGLPGTIDNDVAGTDYTIGFFTALETVVEAIDRLRDTSSSHQRISIVEVMGRYCGDLTLAAAIAGGCEFIVLPEIEFNREDLVCEIKAGIDKGKKHAIVAITEHICDIDELARHIEQETKRETRATVLGHIQRGGSPVAYDRILASRMGAYAIELLLQGYGGRCVGIQNEKMVHHDIIDAIENMKRPFKGDWLETAKKLY
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_ANAD2
Sequence: MLLAIDVGNTNTTLGVYDGAVLRRHWRVETSHTRTYDEYGILLRQLFASAGLEPARVSAVVIASVVPPLAFTLEQMCVRYFDRKPMFVGPGMKTGMPILYENPREVGADRVVNAVAAYERWRCALVVVDFGTATTFDVISAKGEYLGGAICPGIGISMDALARSASKLPRVEFAKPPSVVGKNTVASIQAGLVYGYVGMVDGICAQIAAELATPPKVVATGGLAPLIAGVSRSITEVDEHLTLEGLRILHERNR
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ROC2_ORYSJ
Sequence: MMIPARHMPSMIGRNGAAYGSSSALSLSQPNLLDNHQFQQAFQHQQQQHHLLDQIPATTAESGDNMIRSRASDPLGGDEFESKSGSENVDGVSVDDQDPNQRPRKKRYHRHTQHQIQEMEAFFKECPHPDDKQRKELSRELGLEPLQVKFWFQNKRTQMKNQHERHENSQLRSDNEKLRAENMRYKEALSSASCPNCGGPAALGEMSFDEHHLRIENARLREEIDRISAIAAKYVGKPMVPFPVLSNPMAAAASRAPLDLPVAPYGVPGDMFGGGGAGELLRGVQSEVDKPMIVELAVAAMEELVRMAQLDEPLWSVAPPLDATAAAMETLSEEEYARMFPRGLGPKQYGLRSEASRDSAVVIMTHANLVEILMDANQYAAVFSNIVSRAITLEVLSTGVAGNYNGALQVMSVEFQVPSPLVPTRESYFVRYCKQNADGTWAVVDVSLDSLRPSPVLKCRRRPSGCLIQEMPNGYSKVTWVEHVEVDDRSVHNIYKLLVNSGLAFGARRWVGTLDRQCERLASVMASNIPTSDIGVITSSEGRKSMLKLAERMVVSFCGGVTASVAHQWTTLSGSGAEDVRVMTRKSVDDPGRPPGIVLNAATSFWLPVPPKRVFDFLRDESSRSEWDILSNGGIVQEMAHIANGRDQGNCVSLLRVNSSNSNQSNMLILQESCTDASGSYVIYAPVDVVAMNVVLNGGDPDYVALLPSGFAILPDGPAHDGGDGDGGVGVGSGGSLLTVAFQILVDSVPTAKLSLGSVATVNSLIACTVERIKAAVSGESNPQ
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Homeobox-leucine zipper protein ROC2, GLABRA 2-like homeobox protein 2, HD-ZIP protein ROC2, Homeodomain transcription factor ROC2, Protein RICE OUTERMOST CELL-SPECIFIC 2.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class IV subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SIS1_YEAST
Sequence: MVKETKLYDLLGVSPSANEQELKKGYRKAALKYHPDKPTGDTEKFKEISEAFEILNDPQKREIYDQYGLEAARSGGPSFGPGGPGGAGGAGGFPGGAGGFSGGHAFSNEDAFNIFSQFFGGSSPFGGADDSGFSFSSYPSGGGAGMGGMPGGMGGMHGGMGGMPGGFRSASSSPTYPEEETVQVNLPVSLEDLFVGKKKSFKIGRKGPHGASEKTQIDIQLKPGWKAGTKITYKNQGDYNPQTGRRKTLQFVIQEKSHPNFKRDGDDLIYTLPLSFKESLLGFSKTIQTIDGRTLPLSRVQPVQPSQTSTYPGQGMPTPKNPSQRGNLIVKYKVDYPISLNDAQKRAIDENF
What is the function of this protein?
Required for nuclear migration during mitosis.  It is required for the normal initiation of translation.  Might mediate the dissociation of a specific protein complex of the translation machinery.  Essential for viability.
What are the official names of this protein?
Protein SIS1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localized throughout the cell but is more concentrated at the nucleus.
Protein: FMT_CORA7
Sequence: MRIIFAGTPEPAVVALQKLIESHHEVAAVITRPDARRGRGRSLHPSPVKALAEEHGIEVLTPTTLKQGTEDGDALRARLAEIAPEAIPVVAYGNLITEDLLSLPKHGWVNLHFSLLPTWRGAAPVQAAIAAGDERTGATTFRIDQGLDTGDILATMEETIRPTDTADDLLTRLAYAGGDLLVETMNGLEDGSIIPQPQEGEATYAHKIATEDARIDWTAKVDVIDRHIRAHTPGPGAWTLLGESRLKVGPVSVVEPAELGELSDTTALTSLQPGEVHVAKKEVMVGTGSTPVRLGQIQPPGKKMMNAADWGRGLSSQASQAAEGGQVEVKFS
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: Y2305_RHOCS
Sequence: MKNLGNMMKQAQQMQARMQEMQSKLAEVEVNGVSAGGMVSILLNGKGELKQIKLDKSVVDPEDVEVLEDLIVAAFNDAKNKVEAHMAEETAKLMGGLKLPPGFKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein RC1_2305.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: KDHC_PAENI
Sequence: MMAKAKALIPDNGRAGADEGNRQAWIGQEVLRREDRRLLTGTATFAGDLGVPGQLHMRIVRSTQAHARIVSIDATEAEKTPGVRMVITSEHTRHLGSVLLEELGYHEIYENIEDFSHPVLAVDKVLYVGQPVVAVLAVDPYLAEDAAELVSIEYEPLPVLLDPEEALTGKVELFPGRGNEGARIKKAYGDIDRAFAEAEHVIRHKYVTNRHSGVPMEPRAVVVQPDPARDTLFIWGTVHVHDNRRIIAKMLNLPEVNVRMKHVEIGGSFGVKGGVFPENVVAAWAARTLGVPIKWTEDRVEHMTSTSHAREMVHKLELALDAEGRILGMKDEIFHNHGAYFRQAEPLVSDITAGIVFGPYRVPAYDATLHAVFTNKTPVGAYRAPGRYESTFARERIFDLACAEIGLSKTEFRRRNLLTAEDLPWTPGLDIVHEPYHFDSGDVVKHFNEALEAANFSEWLEESKRLRADGRKVGVGLGVLMDKAGLGLFETGGVEVSRAGRVTVKTGGSSVGQGIETVLAQIVAEELQIAPENIDIVHSDTELIPDGVGSWSSRSTVLAGGAARKAALAVVEKARRLASEMLEADPDDLELTAGSFKVKGTDQQISLYEIAAARDPFTARADNDEPGLAADAVYMNNAMNYPYGVTLVQIELDPDTGGHRILRFSTSTEAGRVINPLTTRGQIIGAAVQGIGGALYEEFLYEEDGQPITTSFMDYLLPSAQEMPNVDCFVTEDAKSPDNPFGAKGLGEIGIIAAGAAIASAIDDAIADGVHTDRLPVTPEQIFSRCQGLNKAER
What is the function of this protein?
Molybdo-flavoprotein enzyme complex involved in nicotine degradation.  The subunit gamma (large subunit) contains the substrate-binding sites, the subunit alpha (medium subunit) binds FAD and the subunit beta (small subunit) has a 2Fe-2S ferredoxin-type domain which binds 2 2Fe-2S clusters.
What are the official names of this protein?
6-hydroxypseudooxynicotine dehydrogenase complex subunit gamma, Ketone dehydrogenase large molybdopterin subunit.
Protein: LAPA_ECOLI
Sequence: MKYLLIFLLVLAIFVISVTLGAQNDQQVTFNYLLAQGEYRISTLLAVLFAAGFAIGWLICGLFWLRVRVSLARAERKIKRLENQLSPATDVAVVPHSSAAKE
What is the function of this protein?
Involved in the assembly of lipopolysaccharide (LPS).
What are the official names of this protein?
Lipopolysaccharide assembly protein A.
What is the protein family that this protein belongs to?
Belongs to the LapA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Copurifies with LptE/LptD, LptBFGC, LptA, DnaK/DnaJ and LPS.
Protein: SMG_SHIB3
Sequence: MFDVLMYLFETYIHTEAELRVDQDKLEQDLTDAGFDREDIYNALLWLEKLADYQEGLTEPMQLASDPLSMRIYTPEECERLDASCRGFLLFLEQIQVLNLEIREMVIERVLALDTAEFDLEDLKWVILMVLFNIPGCENAYQQMEELLFEVNEGMLH
What are the official names of this protein?
Protein Smg.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: SYP_NEOSM
Sequence: MKNKTRVSEYYLPLMKNVSGEVKLRSHKYSLRAGLVKQCGAGLYSWLPLGLKVLRNIESVIRQELDSMGMHEMLMPCIQLAKLWEESGRYSDYGKELLKFKDRHDNELLFGPTNEEVITAIVRDDLASYKQLPKILYHIQWKFRDEIRPRFGLMRAREFLMKDAYSFDVDQQSARISYNKVYQSYLRIFKRLGLNPIPCRANAGVIGGSLNHEFHITTTEGGEGKIFYPEEMGELVDEFCKIDPSNEHAVSVMTEKLQELFCFTEECNSSGIGNDNRICTAQGIEVGHIFLFGEKYSAPMQARFSGRDGKKKNFYMGSYGIGISRLLAAIIEVHSDDKGIIWPESIAPFKIGLINLHGESCGFAEEIFSKLDSVIYDDTADSQGVKFARMDLIGVPFQIIVGKNGPIHGTIELKYRLDSKRESRSLNELVSLFSHT
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_XANCP
Sequence: MSDLISALLLGILEGLTEFLPISSTGHLLIAEQWLGRRSDFFNIVIQAGAILAICLALRQKLWTLATGLGERANRDYVLKIGVAFLVTAVVGLIVRKAGWQLPETIQPVAWALLIGGVWMLVAEHFAGKLPERDVVTWKVAIAVGLAQVVAGVFPGTSRSASAIFLAMLLGLSKRSAAADFVFMVGIPTMFAASGYALLEMYKEGGFGSENWTDVSVAFIAATLTGFVVVKWLLGYIKKHRFTVFAVYRILLGAALLLWLPAA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL6_GEOMG
Sequence: MSRIGKRPIEIPSGVKVSYVTPILKVEGPKGSLLREIMSDIALEIEEKSVSVNRADDAIKSRSAHGLTRTLINNMVVGVTKGFEKILEINGVGYRAEAKGDVLSLSLGYSHPINFPLPKGITVEVDKMTKVFVRGIDKELVGQTAAKIRSFRGPEPYKGKGIKYADERILRKAGKTGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: TUSC_SALTY
Sequence: MKRIAFVFSTAPHGSASGREGLDALLATSALTEALGVFFISDGVFQLLPGQKPDAVLARDYIATFKLFDLYDIDQCWICAASLRERGLENINFVVDATPLEPVALRRELGNYDVILRF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusC, tRNA 2-thiouridine synthesizing protein C.
What is the protein family that this protein belongs to?
Belongs to the DsrF/TusC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JTX21_CARRA
Sequence: MILKHLPWLFIVLAITSAKHGKRSDVNSLLTKVETALKEASGSNEAALEALEGLKGEIQTKPDRVGQATKILGSVGSALGKLNSGDATKIISGCLDIVAGIATTFGGPVGMGIGAVASFVSSILSLFTGSSAKNSVAAVIDRALSKHRDEAIQRHAAGAKRDFAESSAFIQVMKQQSNLTDSDLSIIAANVPVYKFSNFIGQLESRISQGAATTSLSDAKRAVDFILLYCQLVVMRETLLVDLAILYRKGNAEHVASAVENANRVNKELAADTLDFLHKLIPEQALIGAVYHPISASETSKAILNYTKYFGVPDVPRPIGNRRYKFTNSYWNTYSICSEAYMGNYMFRGCSNVRNPNIRVSKMSDGFYTMENSDRRKLYITKHDQGWGWGTLDEDPGDQGHMRFIPLRHGKYMVSSKRWPNWFMYMESSASGYIRSWENNPGPQGHWSIT
What is the function of this protein?
Has potent hemolytic activity (PubMed:10964707).  Is lethal to mice and crayfish (PubMed:10964707).  Causes cutaneous inflammation in humans (PubMed:10964707).  May act as a pore-forming toxin, disrupting normal transmembrane ion concentration gradients in susceptible cells (Probable).
What are the official names of this protein?
Toxin CrTX-A, CRT-1, CrTX-B, Toxin 1, Toxin-A, Toxin-B.
What is the protein family that this protein belongs to?
Belongs to the jellyfish toxin family. Type II subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst. Target cell membrane. Note=Forms a membrane channel in the prey.
Protein: SYQ_XANCP
Sequence: MSEIPATDATAPAEKKDFIRQIVREDLASGKHTAIRTRFPPEPNGYLHIGHAKAICLDFGLAAEFGGLCNLRLDDTNPAKEDPEFVVAIQDDVRWLGFEWAQLRHASDYFEVYYLAAEKLIRDGHAFVCDLSAEQVRQYRGTLTEPGRNSPFRERSVDENLDLFRRMRAGEFPDGARTLRAKIDMASGNINLRDPALYRIKHVEHQNTGNAWPIYPMYDFAHSLGDAVEGITHSLCTLEFEDHRPLYDWCVDKVDLSGHPELLAPLLGKGYPKEAAKPRQIEFSRLNINYTVMSKRKLTALVEEQLVDGWDDPRMYTLQGLRRRGYTPAAMRLFVDRVGISKQNSVIDFSVLEGCLREDLDAAAARRMAVIDPLKLVLTNLPEGHTETLQFSNHPKDESFGTREVPFARELWIEREDFAEVPPKGWKRLVPGGEIRLRGAGIARVDEVIKDAAGEIVELRGWLDPESRPGMIGSNRKVKGTIHWVSAVHAVEAEIRLYDRLFSVEKPDDESEGKTYRDYLNPESKRSVRGYVEPSAAQAAPEQAFQFERTGYFVADRRDHSAATPAFNRSVTLRDTWAK
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_PSYCK
Sequence: MSKLRKGDTVIVIAGKDKGKQGTVQAVKNDRIKVEGINIVTKHQKPNQATGVEGGILKQEAFLHISNVAILNAQTQKADRITYQFGEDGKKQRLYRSNGEVVATA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: PSBN_OLIPU
Sequence: METATLVAIFISGLLVSFTGYALYTAFGQPSQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MTND_TUBMM
Sequence: MKVYEYDNSTEDQREDHDSGAVVSEAALNEIGVLAYHFDSVDDVNALAAERGYKNRDEVTISPSALGDIYEDKVKAFFHEHLHEDEEIRYILDGEGFFDVRSKDDSWVRIRLSKGDLIILPAGIYHRFTTDKNNYIKAMRLFQEDPKWTPLNRDPLVDENAYRKAYINSLPLA
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RUVB_PSEA8
Sequence: MIEPDRLISAVSGRERDEQLDRAIRPLKLADYIGQPSVREQMELFIHAARGRQEALDHTLIFGPPGLGKTTLANIIAQEMGVSIKSTSGPVLERPGDLAALLTNLEAGDVLFVDEIHRLSPIVEEVLYPAMEDFQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGMLTNPLRDRFGIVQRLEFYNVEDLATIVSRSAGILGLEIEPQGAAEIAKRARGTPRIANRLLRRVRDFAEVRGQGDITRVIADKALNLLDVDERGFDHLDRRLLLTMIDKFDGGPVGIDNLAAALSEERHTIEDVLEPYLIQQGYIMRTPRGRVVTRHAYLHFGLNIPKRLGPGVTTDLFTSEDGN
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RK36_NICTO
Sequence: MKIRASIRKICEKCRLIRRRGRIIVICSNPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: C562_ECOL6
Sequence: MRKSLLAILAVSSLVFSSASFAADLEDNMETLNDNLKVVEKADNAVQVKDALTKMRAAALDAQKATPPKLEGKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYHQKYR
What is the function of this protein?
Electron-transport protein of unknown function.
What are the official names of this protein?
Soluble cytochrome b562, Cytochrome b-562.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b562 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: STP2_MACMU
Sequence: MDTKTHSLPITHTQLHSNSRPQSRTCSQCTCTHHRQTFSQSCRQSQRGSRSRSSSQSPATHQNPTGAHSSSGLQSQSPNASPPPKRHKKTMNSHHSPTRPTILHSSCPKNRKNLEGKLNKKKMAKRIQQVYKTKKRS
What is the function of this protein?
Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals.  In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.
What are the official names of this protein?
Nuclear transition protein 2, TP-2, TP2.
What is the protein family that this protein belongs to?
Belongs to the nuclear transition protein 2 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Chromosome. Note=Loaded onto the nucleosomes of condensing spermatids (By similarity). Nuclear import is mediated by IPO4. Nucleolar localization requires the protein to be phosphorylated (By similarity).
Protein: SCXY_CENNO
Sequence: MNSLLIITACLVLIGTVWAKDGYLVDVKGCKKNCYKLGENDYCNRECKMKHRGGSYGYCYGFGCYCEGLSDSTPTWPLPNKRCGGK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Toxin CngtIV.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: UN93A_HUMAN
Sequence: MDRSLRNVLVVSFGFLLLFTAYGGLQSLQSSLYSEEGLGVTALSTLYGGMLLSSMFLPPLLIERLGCKGTIILSMCGYVAFSVGNFFASWYTLIPTSILLGLGAAPLWSAQCTYLTITGNTHAEKAGKRGKDMVNQYFGIFFLIFQSSGVWGNLISSLVFGQTPSQETLPEEQLTSCGASDCLMATTTTNSTQRPSQQLVYTLLGIYTGSGVLAVLMIAAFLQPIRDVQRESEGEKKSVPFWSTLLSTFKLYRDKRLCLLILLPLYSGLQQGFLSSEYTRSYVTCTLGIQFVGYVMICFSATDALCSVLYGKVSQYTGRAVLYVLGAVTHVSCMIALLLWRPRADHLAVFFVFSGLWGVADAVWQTQNNALYGVLFEKSKEAAFANYRLWEALGFVIAFGYSMFLCVHVKLYILLGVLSLTMVAYGLVECVESKNPIRPHAPGQVNQAEDEEIQTKM
What are the official names of this protein?
Protein unc-93 homolog A, HmUnc-93A, Unc-93A.
What is the protein family that this protein belongs to?
Belongs to the unc-93 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FLIW_GEOTN
Sequence: MKIATKYHGDIEIHEKDIVRFEQGIPGFLEEKQFVLLPLEDTPFIILQSVNTPALGFVLIEPFSYFPTYEIDLDDNTLEQLQITGEQDVALYVILTVADPFDDTTANLQAPIVINVHKRLGKQVILTNTNYKTKHRLFPEKVAK
What is the function of this protein?
Allosterically inhibits CsrA binding to mRNA in a non-competitive fashion by preventing CsrA binding to the 5'-UTR (PubMed:27551070).
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHD3_CAEEL
Sequence: MSDDQHESIDGDETMEEDSMLAEGHEDGEEDVGEDEEEVETEESQGVPTTSEKKKPPPKKKKGGKKSSKKKNNCDYPDPYKSTSAEISAAIGLTDVDVDYEQEEFQSITNLKNFSSLVKPYILKVNPGTNVTKMYPLFQVKYKEFQDHMTAHGKSIQKQQRAKFVPVPVPVTPQEKIIPQKTRSSARRKRRDGSDGEGGGHDSDQEFEALIKQHEKQQDEAEKGKEEARINRAAAKVDKRKAALESARASKRARKEQGVVEENHQENCEVCNQDGELMLCDTCTRAYHVACIDENMEQPPEGDWSCPHCEEHGPDVLIVEEEPAKANMDYCRICKETSNILLCDTCPSSYHAYCIDPPLTEIPEGEWSCPRCIIPEPAQRIEKILSWRWKEISYPEPLECKEGEEASKDDVFLKPPRKMEPRREREFFVKWKYLAYWQCEWLSETLMDVYFTALVRMYWRKVDSENPPIFEESTLSRHHSDHDPYKLRERFYQYGVKPEWMQIHRIINHLSYAKSQQDYLVKWKELSYEHATWERDDTDIANYEDAIIKYWHHRERMLNDEVPRNVQKMIAKQREAKGLGPKEDEVTSRRKKREKIDILKKYEVQPDFISETGGNLHPYQLEGINWLRHCWSNGTDAILADEMGLGKTVQSLTFLYTLMKEGHTKGPFLIAAPLSTIINWEREAELWCPDFYVVTYVGDRESRMVIREHEFSFVDGAVRGGPKVSKIKTLENLKFHVLLTSYECINMDKAILSSIDWAALVVDEAHRLKNNQSTFFKNLREYNIQYRVLLTGTPLQNNLEELFHLLNFLAPDRFNQLESFTAEFSEISKEDQIEKLHNLLGPHMLRRLKADVLTGMPSKQELIVRVELSAMQKKYYKNILTRNFDALNVKNGGTQMSLINIIMELKKCCNHPYLFMKACLEAPKLKNGMYEGSALIKNAGKFVLLQKMLRKLKDGGHRVLIFSQMTMMLDILEDFCDVEGYKYERIDGSITGQQRQDAIDRYNAPGAKQFVFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRLGQKHKVMIYRFVTKGSVEERITSVAKKKMLLTHLVVRAGLGAKDGKSMSKTELDDVLRWGTEELFKEEEAPVEGADGEGTSSKKPNEQEIVWDDAAVDFLLDRNKEEEGQDGEKKEHWTNEYLSSFKVATYNTKEADDADDDEDETEVIKEGTEEQDPNYWEKLLKHHYEQDQETELQKLGKGKRVRRQVNYASENMGQDWSAQNNQQQEEDDGSEYGSDNGELLQTDEDYEERRRRREERSEKLPPLLAKVNGQIEVLGFNPRQRKAFYNAVMRWGMPPQDLTQSSWQVRDLRNKSEKVFKAYSSLFMRHLCEPVVDNSDSFMDGVPREGLNRQAVLSRIGLMSILRKKVQEFEKFNGEWSMPETREKMLATAAQASVSNLPGMIKIKEEPIDIDETPMDVDQSNITKTEELASEVKVEEEPKAPRLPYKFNICDGGYTELHSLWINEEKVARNGKEYEIWHRRHDFWLLAAVAVYGYGRYQINFQDIMNDPKFSIVNEPFKQTGADPATNFADVKNKFLARRFKLLEQSLVIEEQLRRAAHINKQQSPDQVGQLAQHFSELEHTADAHVNIARESNNGNRNANAILHKCLAQLDDLLSDLKTDVARLPATISQVRPVTERLQMSERQILSRLVVAKDPDAAPSKPALPPSGPFITPLFNQNFTTIQPKFPSLFDCNLSPDDEPIDIEGSISAAVAEASRASSIAATKDEPMDTSDKDIPSTSAAAGSSYPRY
What is the function of this protein?
Chromatin-remodeling protein that has a role in notch signaling-dependent vulval cell fate determination.  May also have a role in pharyngeal precursor cell specification.
What are the official names of this protein?
Chromodomain-helicase-DNA-binding protein 3 homolog, CHD-3.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IBP4_PIG
Sequence: MLPLCLVAALLLSASGPRPSLGDEAIHCPPCSEEKLARCRPPVGCEELVREPGCGCCATCALGKGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGLCMELAEIEAIQESLQPSDKDEGDHPNNSFSPCSPQDRRCLQKHLAKIRDRSTSGGKMKVIGAPREEARPVPQGSCQSELHRALERLAASQRRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGGLEPKGELDCHQLADSFRE
What is the function of this protein?
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture.  They alter the interaction of IGFs with their cell surface receptors.
What are the official names of this protein?
Insulin-like growth factor-binding protein 4, IBP-4, IGF-binding protein 4, IGFBP-4.
What are the subcellular locations of this protein?
Secreted.
Protein: SYS_BUCAP
Sequence: MLNPYLLRNQIDAISKKLLKKKFKLDISLISSLEKKRKKLQIKTDNLQYKHNTLSALFKKEKKIQELDENLKRTLTKSSKNLSELKIELNLLQEKIHNFSLSIPNIPSDDVPEGNSSENNKIVKYWGKKREYSFAVRDHVEIGNKLNQLDWKSSAKISGARFIVMKGNIALLHRALSQFMLDLHTIKHGYTETYVPYLVNHDSLYGTGQLPKFTDDLFHINSIDKKKYVLIPTAEVPLTNLFSNQILNETELPIMLTAHTPCFRSEASSYGRDSKGLIRLHQFDKVELVQIIQPELSMNALELLTHHAEKVLQLLELPYRKVLLCGGEMGFSATKTYDLEVWFPSQKKYREISSCSNMSDFQARRMKTRYKKKKEKSNSFVHTLNGSGLAIGRTLAAILENYQDSDGRVTIPKILQKKYMQGIEYIN
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.