PharMolix/UniProtQA huggingface dataset:
Protein: CDC16_DICDI
Sequence: MADNLYDSSIIEKQLKEKIENALSIHSYPTAIFFSDKLLNLVTIHSKEYVKILYILCDALYLDRQFQRSSYLIQKYLNAIEEIDKKGEDYQYIDDIHSHHHNQQQNIFYKRIKKEKEDEQYTNTILKLKYLAAKCKIETNEFDQCLQILNKDNDSSENMDDENNNINNNNNKIKKENEINNDNCDDDDDDDDDDDDDDDDEKDSNQLLKFYTNSKSNKSKDISENNSNNENTTKESINKNNTDSSSIDNKNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNFNKETLIIRSSISCLKGKCYESMDNLKKAKFWYIKALLTDYNCFEAFESLTKNHLLTYQEEISLLEKLKFSSDDSWIKEIYSLSLKKYDSPKFTFNYKYLELYDSLNHQNSNNNTFGANNNNNNNNNNNNNNNNNNNNNSNNDISTEDLISVKTLSSSSSSPSKKQENNNLITINEIRKKLIECNDIQTWISEYYFYRHQFQESYSITKRILKQDKYYSNQICLMVNISSMFELQLTNELYFTCHQLVDSFTSSLNNGSHGGSHGGGGGGSHGGSSGNGGAISWYGVACYYHLIQNSDQTQRFFTKSTTLDSRMGASWLGFGHFFASKGEHDQAMAAYRTSSRLLTGCHLPLLCIGMELIRVHNLNLASQYILQAKDICPYDPMIFNELGIIEYKNSQYNEAIKLFETALEICKIKSKASSSSSSSSNYHNLNLSNISFSGVGSSGIGNNNNNNNNRRTTTTTTTTSNNQKKNSSNNKTMIAYLESWEPTIYNLAHCYRKLRKFELALHYYTMSLSLLPNNPSTYSALGFTHHLQGNFDEAIDYYHQSLSIRDDTFTNVLLHKALSLSILQYD
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
What are the official names of this protein?
Anaphase-promoting complex subunit 6, APC6, Cell division cycle protein 16 homolog.
What is the protein family that this protein belongs to?
Belongs to the APC6/CDC16 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FRM4B_MOUSE
Sequence: MASVFMCGVEDLLFSGSRFVWNLTVSTLRRWYTERLRACHQVLRTWCGLRDVYQMTEGRHCQVHLLDDRRLELLVQPKLLSRELLDLVASHFNLKEKEYFGITFIDDTGQENWLQLDHRVLEHDLPKKPGPTLLHFAVRFYIESISFLKDKNTVELFFLNAKACVHKGQIEVDSETIFKLAALVLQESKGDYTSDENARKDLKTLPVFPTKTLQEHPSLAYCEDRVIEHYLKIKGLTRGQAVVQYMKIVEALPTYGVHYYAVKDKQGLPWWLGISYKGIGQYDLQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLFVQTWYANSSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDDIAMDLTETGTQRGSKLVTLEAKSQFIMASNGSLISSGSQDSEGMEEQKREKILELKKKEKLLQEKLLQKVEELKKICLREAELTGRMPKEYPLNIGEKPPQVRRRVGTTFKLDDNLLPTEEDPALQELESNFLIQQKLVEAAKKLASEPDLCKTVKKKRKQDYTDAVKRLQEIENSINEYRIRCGKKPSQKAAVVPPEDIIPSESSSLSDTTTYDDPNDSFTLAGQRPSSVPHSPRILPPKSLGIERIHFRKSSINEQFMDTRHSREMLSTHSSPYKTLERRPQGGRSMPTTPVLTRNAYSSSHLEPDSSSQHCRQRSGSLESQSHLLSEMDSDKPFFTLSKSQRSSSTEILDDGSSYTSQSSSEYYCVTPAASPYYTTQTLDTRARGRRRSKKHSVSTSNSGSMPNLAQKDPLRNGVYSKGQDPPPSGYYIAGYPPYAECDLYYSGGYVYENDTEGQYSVNPSYRSSAHYGYDRQRDYSRSFHEDEVDRVPHNPYATLRLPRKAAVKSEHITKNIHKALVAEHLRGWYQRASGQKDQGHSPQTSFDSDRGSQRCLGFAGLQVPCSPSSRASSYSSVSSTNASGNWRTQLTIGLSEYENPVHSPYTSYYGSIYNPLSSPSRQYAETTPLDGTDGSQLEDNLEGSEQRLFWHEDSKPGTLV
What is the function of this protein?
Member of GRP1 signaling complexes that are acutely recruited to plasma membrane ruffles in response to insulin receptor signaling.  May function as a scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex (PubMed:20080746).  Plays a redundant role with FRMD4A in epithelial polarization (PubMed:20080746).
What are the official names of this protein?
FERM domain-containing protein 4B, GRP1-binding protein GRSP1, Golgi-associated band 4.1-like protein, GOBLIN.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell junction, tight junction. Cell junction, adherens junction. Note=Colocalized with PARD3 at adherens junction and tight junction (PubMed:20080746).
Protein: RL22_YERPB
Sequence: METIAKHRHARSSAQKVRLVADLIRGKKVSQALETLTYTNKKAAGLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: LBD6_MAIZE
Sequence: MASSVPAPSGSVITVASSSSSAAAAAVCGTGSPCAACKFLRRKCQPDCVFAPYFPPDNPQKFVHVHRVFGASNVTKLLNELHPFQREDAVNSLAYEADMRLRDPVYGCVGVISILQHNLRQLQQDLARAKYELSKYQAAAAASASTAPTGPQAMAEFIGNAMPNGAHNFINIGHSAALGSLGGSASVFGQEQFGNAQMLSRSYDGGEPIARLGINGGGYEFGYSTAMGGSGAVSGLGTLGISPFLKSGTAGGDEKPNGGQ
What is the function of this protein?
Promotes the switch from proliferation to differentiation in the embryo sac.  Negative regulator of cell proliferation in the adaxial side of leaves.  Regulates the formation of a symmetric lamina and the establishment of venation.  Interacts directly with RS2 (rough sheath 2) to repress some knox homeobox genes.
What are the official names of this protein?
LOB domain-containing protein 6, Protein ASYMMETRIC LEAVES 2, Protein indeterminate gametophyte 1, ZmIG1.
What is the protein family that this protein belongs to?
Belongs to the LOB domain-containing protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TUBR_PRIM1
Sequence: MSDYFEEVMRKLTIEDVSILGWLFQNEANAVFKAIKKSSIADELEYSTANFRKTLNKLEAIHFIGTVTGGKEHKLYLTEYGQQAVQQAIHHGEENEEVEEI
What is the function of this protein?
A DNA-binding protein that is part of the type III plasmid partition system used to ensure correct segregation of the pBM400 plasmid.  Binds the plasmid origin of replication, probably cooperatively, forming a ring or short helix with external DNA (PubMed:23010931).  Its effect on RNA expression has not been shown (Probable).
What are the official names of this protein?
DNA-binding protein TubR.
Protein: HIS6_FLAJ1
Sequence: MLAKRIIPCLDIKNGRTVKGVNFVDLRDAGDPVELAEIYSREGADELVFLDISATEERRKTLVNMVRSVAEKINIPFTVGGGISSVEDVDILLNNGADKVSINSSAVKNPQLINDLAQKFGSQCVVVAIDAKQIDGQWIVHLVGGKVPTELNLFDWAVEVAERGAGEILFTSMDNDGTKNGFANEALAKLSELVNIPIIASGGAGNIQHFVDSFKEGKADAALAASVFHFKEIEIKALKQELRKNGVEVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K1C10_MOUSE
Sequence: MSVLYSSSSKQFSSSRSGGGGGGGSVRVSSTRGSLGGGYSSGGFSGGSFSRGSSGGGCFGGSSGGYGGFGGGGSFGGGYGGSSFGGGYGGSSFGGGYGGSSFGGAGFGGGGSFGGGSFGGGSYGGGFGGGGFGGDGGSLLSGNGRVTMQNLNDRLASYMDKVRALEESNYELEGKIKEWYEKHGNSSQREPRDYSKYYKTIEDLKGQILTLTTDNANVLLQIDNARLAADDFRLKYENEVTLRQSVEADINGLRRVLDELTLSKSDLEMQIESLNEELAYLKKNHEEEMRDLQNVSTGDVNVEMNAAPGVDLTQLLNNMRNQYEQLAEKNRKDAEEWFNQKSKELTTEIDSNIEQMSSHKSEITELRRTVQGLEIELQSQLALKQSLEASLAETEGRYCVQLSQIQSQISALEEQLQQIRAETECQNAEYQQLLDIKTRLENEIQTYRSLLEGEGSSSGGGGGRRGGSGGGSYGGSSGGGSYGGSSGGGGSYGGSSGGGGSYGGGSSGGGSHGGSSGGGYGGGSSSGGAGGHGGSSGGGYGGGSSSGGQGGSGGFKSSGGGDQSSKGPRY
What is the function of this protein?
(Microbial infection) Binds S. pneumoniae PsrP, mediating adherence of the bacteria to lung cell lines.
What are the official names of this protein?
Keratin, type I cytoskeletal 10, 56 kDa cytokeratin, Cytokeratin-10, CK-10, Keratin, type I cytoskeletal 59 kDa, Keratin-10, K10.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Secreted, extracellular space. Cell surface. Cytoplasm.
Protein: GDL43_ARATH
Sequence: MSTSKAITLTLFIATTLLAPCNAAANATTKPLFPAILIFGDSTVDTGNNNYPLPTIFRAEHFPYGMDLPDGKANGRFSNGKLISDIIATKLNIKEFIPPFLQPNLSDQDILTGVCFASAGAGYDDLTSLSTQAIRVSEQPNMFKSYIARLKGIVGDKKAMEIINNAFVVVSAGPNDFILNYYEIPSRRLEYPFISGYQDFILKRLENFVRELYSLGVRNVLVGGLPPMGCLPIHMTAKFRNIFRFCLEHHNKDSVLYNEKLQNLLPQIEASLPGSKFLYADVYNPMMEMIQNPSKYGFKETKRGCCGTGFLETSFMCNVFSPVCQNRSEFLFFDSIHPSEATYNVIGNLLDPLIRGKFQA
What are the official names of this protein?
GDSL esterase/lipase At2g31540, Extracellular lipase At2g31540.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEM3_DICCH
Sequence: MVDTILRIATRQSPLALWQAHFVQQRLEACHPGLRVELVPMVTRGXLLLDTPLAKVGGKGLFVKELELALLENRADIAVHSMKDVPVEF
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: GLGA_LIGS1
Sequence: MKLLFAGSECAPFFKTGGLGDVMGALPKTIAKTTDNDVRVVLPFFTGMAEEYKSQLSFVTSFYVKVGWRDQYCGVLKLEMDNVTYYFIDNLYYFDRPGLYGYYDEGERWAFFQQAIIEMLEKIGFIPDILHVNDYHTAFIPFLLKEKYGWINAYQSIKTVLTIHNLQFQGEYGREVLGELFNLDASYYDDGTVRFDTAVNFMKTGILYADKVNTVSPTYASEIQTEAFGQGLDEILRMHNWKLRGILNGIDYERNNPATDKNLVANYSAKKLKGKVKDKLALQKEFGLPQRKDVPVIAMVSRLTAQKGFQLVVSEMQNLVQFDVQVIVLGTGDANFEHDFRYFADTYPDKVGAAITFDVGLAQRIYAGADMFLMPSAFEPCGLSQMISMRYGTLPIVHQIGGLQDSVQPFNPVTGEGTGFGFHDFSGFYMMQEIQEALRLYAESVAWTKVVKQAMSQDFSWETASQEYLNMYNELV
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: TNP7_ECOLX
Sequence: MPRRSILSATERESLLALPDAKDELIRHYTFNETDLSVIRQRRGAANRLGFAVQLCYLRFPGTFLGVDEPPFPPLLRMVAAQLKMPVESWSEYGQREQTRREHLVELQTVFGFKPFTMSHYRQAVHTLTELALQTDKGIVLASALVENLRRQSIILPAMNAIERASAEAITRANRRIYAALTDSLLSPHRQRLDELLKRKDGSKVTWLAWLRQSPAKPNSRHMLEHIERLKSWQALDLPAGIERQVHQNRLLKIAREGGQMTPADLAKFEVQRRYATLVALAIEGMATVTDEIIDLHDRIIGKLFNAAKNKHQQQFQASGKAINDKVRMYGRIGQALIEAKQSGSDPFAAIEAVMPWDTFAASVTEAQTLARPADFDFLHHIGESYATLRRYAPQFLGVLKLRAAPAAKGVLDAIDMLRGMNSDSARKVPADAPTAFIKPRWAKLVLTDDGIDRRYYELCALSELKNALRSGDVWVQGSRQFKDFDEYLVPVEKFATLKLASELPLAVATDCDQYLHDRLELLEAQLATVNRMASANDLPDAIITTASGLKITPLDAAVPDAAQAMIDQTAMLLPHLKITELLMEVDEWTGFTRHFTHLKTSDTAKDKTLLLTTILADAINLGLTKMAESCPGTTYAKLSWLQAWHIRDETYSTALAELVNAQFRQPFAGNWGDGTTSSSDGQNFRTGSKAESTGHINPKYGSSPGRTFYTHISDQYAPFSAKVVNVGIRDSTYVLDGLLYHESDLRIEEHYTDTAGFTDHVFGLMHLLGFRFAPRIRDLGETKLFIPKGDAAYDALKPMISSDRLNIKQIRAHWDEILRLATSIKQGTVTASLMLRKLGSYPRQNGLAVALRELGRIERTLFILDWLQSVELRRRVHAGLNKGEARNALARAVFFYRLGEIRDRSFEQQRYRASGLNLVTAAIVLWNTVYLERATSALRGNGTALDDTLLQYLSPLGWEHINLTGDYLWRSSAKVGAGKFRPLRPLPPA
What is the function of this protein?
Required for transposition of transposon Tn3926.
What are the official names of this protein?
Transposase for transposon Tn3926.
What is the protein family that this protein belongs to?
Belongs to the transposase 7 family.
Protein: RS20_RUBXD
Sequence: MPAPTKRERQNRKRFERNRSVRTRLRNLSKKFYRALDAGDLESARSVRDEAQKAYDKAAGKGIIHRNKASRKLSRFDRALAGRG
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: Y2936_MYCBO
Sequence: MARTQQQRREETVARLLQASIDTIIEVGYARASAAVITKRAGVSVGALFRHFETMGDFMAATAYEVLRRQLETFTKQVAEIPADRPALPAALTILRDITAGSTNAVLYELMVAARTDEKLKETLQNVLGQYSAKIHDAARALPGAESFPEETFPVIVALMTNVFDGAAIVRGVLPQPELEEQRIPMLTALLTAGL
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator Mb2936c.
Protein: ATPF_GOSBA
Sequence: MKNVTDSFVSLGHWPSAGSFGVNTDILATNPINLSVVLGVLIFFGKGVLSDLLDNRKERILNTIRNSEELRGGAIERLEKARARLRKVEMEADQFRVNGYSEIEREKLNLINSTYKILEQLENYKNETIYFEQQRAINQVRQRVFQQALQGALGTLNSSLNNELHLRTISANIGLFGVMKEITD
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL24_BUCA5
Sequence: MALKLRRNDSVVILTGKDKGKTGIIKNILSLNQVIVKGLNLIKKHQKPVPSQNKSGGIIEKEAPIHISNIAILNPESNKADRIGFRFEEGRKVRFFKSTGKTIQ
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RR3_MORIN
Sequence: MGQKINPLGFRLGATQGHHSLWFAQPKNYSEDLQEDQKIRDCIKNYIKKNMKIFSSVEGIACIEIQKRIDLIQVIIYMGFPKLLIEHQKIEELQMNIQKELNSVNRKLNMAITRIANPYGHPNILAEFIAGQLKNRVSFRKAMKKAIELTEQAGTKGIQIQIAGRIDGKEIARVEWIREGRVPLQTIKAKIDYCSYTVRTIYGALGIKIWIFVDE
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ENO1_METCA
Sequence: MKARIESVQAMPIYDSRGVPTVRVRLTLTDGTAATASIPSGASTGENEAVELRDGDPKAHGGKGVLKAVSNVNDVIAPAVMGLEPWRQAEIDRLMIELDGTANKERLGANAILGVSEAVAAAAAKSAGLPLYAYLGGAGQARLPIPMINILNGGKHADSSLDFQEFMIMPVGAPSFAEAMRYATETFQALKSILKAKGHATSVGDEGGFAPQLQSNDEACDLIVEAITKAGYEPGEDIAIALDPAASSFHENGVYRLTRSGQGDKTSSEMTDLYRRWIDKYPIVSIEDGLAENDWDGFREHTAVLGEKIQIVGDDLLVTNTRFIQRAIEEKSCNAVLIKLNQIGTVTETVEAIHLCRKAGWGFVISHRSGETEDTFMADFAVAMGGGQIKTGSVCRSERMAKYNRLLEIESDLGKAARFGR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase 1, 2-phospho-D-glycerate hydro-lyase 1, 2-phosphoglycerate dehydratase 1.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: HAND1_SHEEP
Sequence: MNLVGSYAHHHHHHHHHHHPHPAHPMLHEPFLFGPASRCHQERPYFQSWLLSPADAAPDFPAGGPPPTTAVRAAAASYGPDARPGQSPGRLEALGGRLGRRKGSGPKKERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDAQAGDPEAFKAELKKADGGRESKRKRELQQHEGFPPALGPGEKRD
What is the function of this protein?
Transcription factor that plays an essential role in both trophoblast giant cell differentiation and in cardiac morphogenesis (By similarity).  Binds the DNA sequence 5'-NRTCTG-3' (non-canonical E-box) (By similarity).  Acts as a transcriptional repressor of SOX15 (By similarity).  In the adult, could be required for ongoing expression of cardiac-specific genes (By similarity).
What are the official names of this protein?
Heart- and neural crest derivatives-expressed protein 1, Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1, eHAND.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, nucleolus. Note=Interaction with MDFIC sequesters it into the nucleolus, preventing the transcription factor activity. Phosphorylation by PLK4 disrupts the interaction with MDFIC and releases it from the nucleolus, leading to transcription factor activity (By similarity).
Protein: GNOM_ARATH
Sequence: MGRLKLHSGIKAIEEEPEDFECTDSSNTTTLACMIDTEIAAVLAVMRRNVRWGGRYMSGDDQLEHSLIQSLKALRKQVFSWNQPWHTISPMLYLQPFLDVIRSDETGAPITSIALSSVYKILNLNVIDQNTANIEDAMHLVVDSVTSCRFEVTDPASEEVVLMKILQVLLACMKNKASVMLSNQHVCTVVNTCFRVVHQAGMKGELLQRVARHTMHELVRCIFSHLPDVERTETTLVNRAGSIKQEKAGVDSDYAIVSKPVEDGNANSEYDVENSMATFATGAQSLMDDGPVGPGSRKPASPYDLHIMTEPYGVPSMVEIFHFLCSLLNVVEHVGMGSRSNTIAFDEDVPLFALNLINSAIELGGSSIRHHPRLLSLIQDELFRNLMQFGLSMSPLILSMVCSIVLNLYQHLRTELKLQLEAFFSCVILRLAQGKYGPSYQQQEVAMEALVNFCRQKSFMVEMYANLDCDITCSNVFEELSNLLSKSTFPVNCPLSAMHILALDGLIAVIQGMAERISNGLTGLDLGPVHLDEYTPFWMVKCDNYSDPNHWVSFVRRRKYIKRRLMIGADHFNRDPKKGLEFLQGTHLLPDKLDPQSVACFFRYTAGLDKNLVGDFLGNHDEFCVQVLNEFAGTFDFQYMNLDTALRLFLETFRLPGESQKIQRVLEAFSERYYMQSPEILANKDAALVLSYSIIMLNTDQHNVQVKKKMTEEDFIRNNRHINGGNDLPREFLSELFHSICNNEIRTTPEQGAGFPEMTPSRWIDLMHKSKKTAPYILADSRAYLDHDMFAIMSGPTIAAISVVFDHAEHEDVYQTCIDGFLAIAKISACHHLEDVLDDLVVSLCKFTTLLNPSSVDEPVLAFGDDAKARMATITIFTIANKYGDYIRTGWRNILDCILRLHKLGLLPARVASDAADESEHSSEQGQGKPLANSLSSAHLQSMGTPRRSSGLMGRFSQLLSLDTEEPRSQPTEQQLAAHQRTLQTIQKCHIDSIFTESKFLQAESLLQLARALIWAAGRPQKGTSSPEDEDTAVFCLELLIAITLNNRDRIVLLWQGVYEHIATIAQSTVMPCNLVDKAIFGLLRICQRLLPYKESLADELLRSLQLVLKLDARVADAYCEQIAIEVSRLVKANANHIRSQAGWRTITSLLSITARHPEASESGFDAVSFVMSEGTHLYPANYVLCVDAARQFAESRVGQSERSIRALDLMGDSLEFLAKWALSAKENMGEEDFGKMSQDIGEMWLRLVQGLRKVCLDQREDVRNHALQSLQKCLGGVDGINLAHSMWSQCFDKVIFTVLDDLLEIAAGSQKDYRNMEGTLLLAIKLLSKVFLQQLQELSQLSTFCKLWLGVLTRMEKYMKVKVRGKKSDKLQESVPELLKNILLVMKTKGVLLQRSALGGDSLWELTWLHVNNIAPSMRLELFPDQESSQLGDDETVSNGLSSPENTTGS
What is the function of this protein?
Activates the ARF proteins by exchanging bound GDP for free GTP.  Plays a role in vesicular protein sorting.  Acts as the major regulator of endosomal vesicle trafficking but is also involved in the endocytosis process.  Could function redundantly with GNL1 in the retrograde Golgi to endoplasmic reticulum trafficking.  Regulates vesicle trafficking required for the coordinated polar localization of auxin efflux carriers which in turn determines the direction of auxin flow.  Mediates the sorting of PIN1 from endosomal compartments to the basal plasma membrane and the polarization of PIN3 to the bottom side of hypocotyl endodermal cells.  Involved in the specification of apical-basal pattern formation in the early embryo and during root formation.  Required for correct cell wall organization leading to normal cell adhesion during seedling development.  Also plays an essential role in hydrotropism of seedling roots.
What are the official names of this protein?
ARF guanine-nucleotide exchange factor GNOM, Pattern formation protein EMB30, Protein EMBRYO DEFECTIVE 30, Protein MIZU-KUSSEI2, Protein VASCULAR NETWORK 7.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Soluble and partially membrane-bound.
Protein: ASTD_ESCF3
Sequence: MTLWINGDWVTGQGALRVKCNPVSGELLWQGNDADAAQVGQACRAARAAFPRWARLSFGDRQVRVERFAGLLESNKVELTAIIARETGKPRWEAATEVTAMINKIAISIKAYHVRTGEQRSEMPDGAASLRHRPHGVLAVFGPYNFPGHLPNGHIVPALLAGNTVIFKPSELTPWSGEAVMRLWQQAGLPSGVLNLVQGGRETGQALSALEDLDGLLFTGSANTGYQLHRQLSGQPEKILALEMGGNNPLIIDDVADIDAAVHLTIQSAFVTAGQRCTCARRLLLKSGAQGDAFLARLVAVSQRLTPGNWDDEPQPFIGGLISEQAAHQVVTAWQELEAMGGRTQLAPRLLRAGTSLLTPGIVEMTGVAGVPDEEVFGPLLRVWRYDTFDEAIRMANNTRFGLSCGLVSSRRDKFEQLLLEARAGIVNWNKPLTGAASTAPFGGVGASGNHRPSAWYAADYCAWPMASLESDSLTLPTTLNPGLDFSEEVER
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: RL4_ECO55
Sequence: MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTRAQKTRAEVTGSGKKPWRQKGTGRARSGSIKSPIWRSGGVTFAARPQDHSQKVNKKMYRGALKSILSELVRQDRLIVVEKFSVEAPKTKLLAQKLKDMALEDVLIITGELDENLFLAARNLHKVDVRDATGIDPVSLIAFDKVVMTADAVKQVEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: BPT_RUEST
Sequence: MRHTLPIAPQFYVTAPQPCPYLEGRMERKLFTSLQGDGVEQLNNSLSQQGFRRSQNVLYRPSCSDCSACMSARISVADFKPTRSQRKTLNRNRHLDRRATSPWATEDQYALFRDYLDQRHADGGMADMDVFEYAAMVEETPIRTRVVEYTDLDTNALTAVSLTDVLEDGLSMVYSFYAPNLPQNSLGTFMVLDHIEIAREAGLPYVYLGYWVPGSQKMGYKAKFSGLEVYFGGEWTPLKDPESFTAEDHPLSTAPVAEQVANIQLPQGTSPKKR
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPG3_DICDI
Sequence: MNIRNSLILIISSIFVLSFINGGLTSDPTCVGAPDGQVYLFSSWDFQGERYVYNISQGYLSLPDGFRNNVQSFISGADVCFVKWYPSEQYQITAGESHRNYAALTNFGQRMDAIIPGNCSNIVCSSK
What are the official names of this protein?
Spore germination protein 3, SPG3.
What is the protein family that this protein belongs to?
Belongs to the Dictyostelium gerABC family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRG_METTP
Sequence: MRYIVVTGGVMSGLGKGITAASIGRLLMNKGYRVTAIKIDPYINIDAGLMSPFQHGEVYVLKDGGEVDLDLGNYERFLDIELTRDHNITTGKVYSTVIEKERRGEYLGKTVQIIPHITDEIKRRIRQVSRTGGSEICLIEVGGTVGDIESMPFLEAMRQLKYEESGNIFFVHVTLAPMTSDGEQKTKPTQHSVKEMRELGLQPDMIVVRCKKPLLPETKAKIAHFCDVPIEAVISGHDSDDIYRVPLQLEAEGLTKYIMKAMRLFPLEERRDWYDLVQRMDSIREKVSMALVGKYTSGSQCTDPMKDAYLSIREALKHAGIEAGVMPEISWIDAEDLERIQPEKVLRDFDGILVPGGFGARGTEGKMNAIRYAREKGIPYLGICFGMQLAVIEFARNVCGLEGASSTEFGETPHPVIALLPEQEKVRQMGATMRLGNYPAHLIEGTLAHRIYGTTEIVERHRHRYEVNPAYIEVLEKNGLLFSGRNGDLMEIMEIPGHPFFFACQFHPEMRSRPGRPSPPFLAFVEAMKAQRLRRTGSTYTLELTA
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: ILVC_BRUMB
Sequence: MRVYYDRDADVNLIKSKKVVIVGYGSQGRAHALNLKDSGAANVRVALREGSATVQKAQADGFEVMNVADAAKWADLMMMATPDELQADIYRDHIHNNLRDGAAIAFAHGLNVHCGLIEPKKTVDVMMIAPKGPGHTVRGEYQKGGGVPCLIAIHQDASGNAHDLALSYASGVGGGRSGVIETTFKEECETDLFGEQAVLCGGVVELIRTGFEVLVEAGYAPEMAYFECLNEMKLIVDLIYEGGIANMNYSISNTAEWGEYVTGPRIITAETKAEMKRVLKDIQTGKFTSDWMQEWKAGAARFKGIRRLNDAHQIEEVGGKLRAMMPWIEKNKLVDKARN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.