PharMolix/UniProtQA huggingface dataset:
Protein: ARAA_FLAJ1
Sequence: MIDISQKEVWFVVGSQELYGEETLRKVAEHSQIIAKGLDASSSIPVKVVYKDVVKSPSQILDVCLAANSAKNCIGIIAWMHTFSPAKMWIGGLNILKKPLCHLHTQYNAEIPWGSIDMDFMNLNQSAHGDREFGFIMSRLRKKRKVVVGHWEDQRVQKQLGIWSRVVLGWDELQNLKVARIGDNMREVAVTEGDKVEAQIRFGMSVNGYDSSDVTKHIEKVTDKQLADLLAVYESSYNLTDSLKEGGAQRSSLVEAAKIELGLRAFLEEGGFGAFTDTFENLGVWKQLPGIATQRLMADGYGFGGEGDWKTAAMVRALKVMCIGLEGGTSFMEDYTYNFTPQKSYVLGSHMLEICPSIADGKPSCEVHPLGIGGKEDPARLVFNSPAGDAINVSLVDMGTRFRLIVNEVEAVKPMAELPKLPVARVLWDCKPNLEVAATAWILAGGAHHTVYSQSITTEYMEDFADIAGIELLVIDEKTTVREFKDKINANEAYFHLFQHGL
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: TFPI1_RABIT
Sequence: MKKEHIFWTSICLLLGLVPAPVSSAAEEDEEFTNITDIKPPLQKPTHSFCAMKVDDGPCRAYIKRFFFNILTHQCEEFIYGGCEGNENRFESLEECKEKCARDYPKMTTKLTFQKGKPDFCFLEEDPGICRGYITRYFYNNQSKQCERFKYGGCLGNLNNFESLEECKNTCENPTSDFQVDDHRTQLNTVNNTLINQPTKAPRRWAFHGPSWCLPPADRGLCQANEIRFFYNAIIGKCRPFKYSGCGGNENNFTSKKACITACKKGFIPKSIKGGLIKTKRKKKKQPVKITYVETFVKKT
What is the function of this protein?
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex.  It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.
What are the official names of this protein?
Tissue factor pathway inhibitor, TFPI, Extrinsic pathway inhibitor, EPI, Lipoprotein-associated coagulation inhibitor, LACI.
What are the subcellular locations of this protein?
Secreted.
Protein: CRTC_RHOCB
Sequence: MIAFIGSVFSPWYRWSGRREPQNHCCINMVTTGTDGRFTMTDRGRSALRQSRDSFQVGPSKLTWTGKELVIDVDEWGALPKLGKLKGRVVLTPRAVTGVEVRLTPDAGHTWRPFAPIADVEVDLAPGHKWTGHGYFDANFGTRALEEDFSFWTWGRFPLKDRTVCFYDATRLDRTKVALAVQINPDGSVCEIDSPPPLVKMKRTPWFVRRETRCDAGAHPAGVYSLLEAPFYSRALMRTQIDGEETVGMHEALDLVRFRQPVLKPMLAVRVPRRAGWKHKD
What is the function of this protein?
Involved in the biosynthesis of carotenoids spheroidene and spirilloxanthin.  Catalyzes the hydration of neurosporene to the corresponding hydroxylated carotenoids 1-HO-neurosporene and that of lycopene to 1-HO-lycopene.  It exhibits negligible activity in converting HO-neurosporene, HO-lycopene, or any other derivative such as spheroidene, 1-HO-3,4-didehydrolycopene.
What are the official names of this protein?
Acyclic carotenoid 1,2-hydratase, Hydroxyneurosporene synthase, Lycopene hydratase, Neurosporene hydratase.
What is the protein family that this protein belongs to?
Belongs to the CrtC hydratase family.
Protein: MURG_COXB2
Sequence: MNRILIIAGGTGGHIFPALAVARELREQEVDVQWLGVKGGLEEKLVPDSFPLHLIQIKAFRGKRGLQQLLMPLRLVRAVFQAYRIIRQFKPDVILGMGGYVAGPGGLAAWITRTPLIIHEQNSIPGLTNRVLAKMAKFILQGFPDTFPQNRKVITTGNPVRTELVKMPLPQVRLAARRGPLRILVLGGSQGARSINQKMLAALSSYPRSEEIAVWHQTGQRDFEFIQKEYEKIKIEAKVDNFISDMAGAYGWADLVVCRAGALTVCEIASVGVASIFIPYPHAVDNHQFHNARFLEQAGAAIIISEESLTETDLMRWFEQFAQDRDRLLTMAENARKLAKPEAVQRVIAQCKKFYAAR
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MCEL_CWPXG
Sequence: MDANVVSSSTIATYIDALAKNASELEQRSTAYEINNELELVFIKPPLITLTNVVNISTIQESFIRFTVTNKEGVKIRTKIPLSKVHGLDVKNVQLVDAIDNIVWEKKSLVTENRLHKECLLRLSTEERHIFLDYKKYGSSIRLELVNLIQAKTKNFTIDFKLKYFLGSGAQSKSSLLHAINHPKSRPNTSLEIEFTPRDNEKVPYDELIKELTTLSRHIFMASPENVILSPPINAPIKTFMLPKQDIVGLDLENLYAVTKTDGIPITIRVTSKGLYCYFTHLGYIIRYPVKRIIDSEVVVFGEAVKDKNWTVYLIKLIEPVNAINDRLEESKYVESKLVDICDRIVFKSKKYEGPFTTTSEVVDMLSTYLPKQPEGVILFYSKGPKSNIDFKIKKENTIDQTANVVFRYMSSEPIIFGESSIFIEYKKFSNDKGFPKEYGSGKIVLYNGVNYLNNIYCLEYINTHNEVGIKSVVVPIKFIAEFLVNGEILKPRIDKTMKYINSEDYYGNQHNIIVEHLRDQSIKIGDVFNEDKLSDVGHQYANNDKFRLNPEVSYFTNKRTRGPLGILSNYVKTLLISMYCSKTFLDDSNKRKVLAIDFGNGADLEKYFYGEIALLVATDPDADAIARGNERYNKLNSGIKTKYYKFDYIQETIRSDTFVSSVREVFYFGKFNIIDWQFAIHYSFHPRHYATVMNNLSELTASGGKVLITTMDGDKLSKLTDKKTFIIHKNLPSSENYMSVEKIADDRILVYNPSTMSTPMTEYIIKKNDIVRVFNEYGFVLVDNVDFATIIERSKKFINGASTMEDRPSTRNFFELNRGAIKCEGLDVEDLLSYYVVYVFSKR
What is the function of this protein?
The heterodimeric enzyme is also involved in early viral gene transcription termination and intermediate viral gene transcription initiation.  Early gene transcription termination requires the termination factor VTF, the DNA-dependent ATPase NPH-I and the Rap94 subunit of the viral RNA polymerase, as well as the presence of a specific termination motif.  Binds, together with RAP94, to the termination motif 5'-UUUUUNU-3' in the nascent early mRNA (By similarity).
What are the official names of this protein?
mRNA-capping enzyme catalytic subunit, Virus termination factor large subunit, VTF large subunit, mRNA-capping enzyme 97 kDa subunit, mRNA-capping enzyme large subunit.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome.
Protein: LIPA2_PROMM
Sequence: MSSTHRPTQYSSILPAERLPEWLRRPIGSVSQLEQMQQLVKGNHLHTICEEGRCPNRGECYAAGTATFLLGGSICTRSCAFCQVMKGQSPQAIDPLEAERVADAVQQMGLRYVVLTSVARDDLPDHGVSIFTETMAAIRQRNPLIEIEVLTPDFWGGVADLAKALEAQRERLTQLLMAAPVCFNHNLETVERLQSKVRRGATYHHSLSLLAAARELAPNIPTKSGLMLGLGEEQEEVVQTLEDLRSVDCQRVTLGQYLRPSLAHIPVHRYWHPEDFKNLAEVACKLGFAQVRSGPLVRSSYHAGEE
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase 2, Lip-syn 2, LS 2, Lipoate synthase 2, Lipoic acid synthase 2, Sulfur insertion protein LipA 2.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLRF_HIRME
Sequence: FLRF
What are the official names of this protein?
FLRFamide.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PLSB_VIBVU
Sequence: MSSGQSFSHSLLKLPLSALVKGTAIPSNPIDDHHIDINKPIVYALPFRSAVDLLTLQKHALELGLPDPLSPLEIHGKSLKRYVFIASRPTLVQSDNDVPSDSIALFSDLLALHAEDSELDVQVIPATVLWGRKPGKEGNNKPYLQAMNGLQKAKAVITAGRDCLVRFSPVVSLRYMAQSHGTDSSIAHKLARVARIHFSRQKLAASGPDLPSRQVLFARLMKSPAIEQAIEEEAKNKNISMEKARKEAQDIMDEIAADFSYSLVKQGDRLLGWLWNKLYQGLNINNAATVRRLAQDGHEIVYVPCHRSHMDYLLLSYVLYHEGMVPPHIAAGINLNFFPAGPIFRRGGAFFIRRSFKGNRLYSTIFREYLAELFAKGYSVEYFSEGGRSRTGRLLPAKTGMLAMTIQAMLRGLNRPVTLVPVYIGYEHVMEVATYAKELRGKRKEKENAGLVLRTLRKLRNFGLGYVNFGEPIPLNQYLNEHAPEWTKDIDPMGASRPQWINPVVNQLANKMMTHINDAAAANALTLCATALLASRQRALSKDSLIHQIECYLQLLKNVPYSKTYTVPSESAEALVEHAISLDKFVIETDTMGDIISLDRNQSILMTYYRNNIIHLFALPSLIAQMIIRQENLTVSQIQQQVAEIYPFLKAELFLSHKEEELDELVVKVLNELVSQDLISLKEDKVAKNQANTLTLVLLGRTISETLQRYSIAFNLLVSNPELAKADLEQKSQDIAQRLTRLHGINAPEYFDKGVFASLFSTLKQQGYLDSDGNCDGEKTAQFATLLYALLYPEVKLTIEESVFQLKSA
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y2669_MYCTU
Sequence: MTDADELAAVAARTFPLACPPAVAPEHIASFVDANLSSARFAEYLTDPRRAILTARHDGRIVGYAMLIRGDDRDVELSKLYLLPGYHGTGAAAALMHKVLATAADWGALRVWLGVNQKNQRAQRFYAKTGFKINGTRTFRLGAHHENDYVMVRELV
What are the official names of this protein?
Uncharacterized N-acetyltransferase Rv2669.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
Protein: ORR13_ORYSJ
Sequence: MSSPHVLVVDDTHVDRHVISMALMRHNVRVTAVESVMQALVFLDSEHDVNMIVSDYCMPEMTGYDLLMEVKKSPRLVHLPVIIASSDNIPERIRKCFDGGAKDYILKPVKIADVPRILNYI
What is the function of this protein?
Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system.  Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes.  Type-A response regulators seem to act as negative regulators of the cytokinin signaling.
What are the official names of this protein?
Two-component response regulator ORR13, OsRR13, OsRRA12.
What is the protein family that this protein belongs to?
Belongs to the ARR family. Type-A subfamily.
Protein: RL17_BRASB
Sequence: MRHGKVHRKLNRTAEHRKAMFANMCAALIKHEQIVTTLPKAKELRPIVEKLVTLGKKGGLALRRQAIAEMRDVDQVKKLFDVLAPRYKDRNGGYTRIIKAGFRYGDNAAMAVIEFVDRDVDAKGQDSGPVQETSEAA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: GATD_THEPD
Sequence: MSQGYSEKVKELLDSVGAAFFDRVKIKLADGLVLEGLLMPRPAFGDPDVVVLKLDNGYNIGISLQRIVSVELLEKFSPREAPTPGEEEGSQEDFGQPEPRVFFVGTGGTIASRVDYVTGAVYPYFTAEELYSMIPELKRLARISSETLFSIFSEDMTPSHWQQLASKIGEIFRRESDVKGVVVAHGTDTLHYSAAAMAFAVQEAPGPIVFVGAQRSSDRPSSDAALNVIGATVVAVHAPFAESVIAMHGSVNDDTILVHRGVRARKMHTSRRDAFMSINSKPIAEVDPLRGSLKLSTSTYKGRGDDVVVQASFSDKVALVKFYPGMSPDIFDFYLEKGFKGLVIEGTGLGHVSTALIDSVRRLVREGVFVAMASQCIFGRVNMNVYRTGVELIKAGVVPAGDMIPETAYVKLSWILGQTEDPEEIQRLFTANLAFEISERSEFDHYPGARW
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).  The GatDE system is specific for glutamate and does not act on aspartate.
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit D, Glu-ADT subunit D.
What is the protein family that this protein belongs to?
Belongs to the asparaginase 1 family. GatD subfamily.
Protein: PGMI_AQUAE
Sequence: MEEVYKVVEGFYNQFEWEDIAKDLTPYKGIVFCGMGGSGIIGSFASKWLEHRSFNKPTFVVKDYTLPPFVDRDYLVFCISYSGNTEETLSNFEEAIGRGIKPLCITSNGKLMERAKEEGCEIYEVPKGFQPRYSLGFMLSKVLNLLGVDKDELEDAKENLKENLESLKQKGKEIANRIYGYIPVVYSTPLTAHIAERWKGQINENSKSPAYFTILPEMHHNEVMGWSNPELRNKFVYLLMFDEKDHHRVKLRVDITKKILEDFGVVPIMLKGEGNSYLARSLYLVHLADWVSVFLAELYGYDPVPVKTIERIKEELKKHA
What is the function of this protein?
Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a similar catalytic efficiency.
What are the official names of this protein?
Bifunctional phosphoglucose/phosphomannose isomerase, Glucose-6-phosphate isomerase, GPI, Mannose-6-phosphate isomerase, Phosphoglucose isomerase, PGI, Phosphomannose isomerase, PMI.
What is the protein family that this protein belongs to?
Belongs to the PGI/PMI family.
Protein: RUVA_NEIM0
Sequence: MISRLTGKLVEKNPPQIVIDVNGVGYEADVSMQTFYNLPPVGESVQLFTQLIIREDAHLLFGFATAEERKTFRQLIKVGGIGAKTALGILSAMTADELAQAVAEEDVKRLSSAPGIGKKTAERMVLELRGKLVAHTVTDGLFAAAPAADETEDIVSTLLALGYSEREAKAAVKGVPEGTDVGEGVRLALKNLLK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: TIG_FRATW
Sequence: MQVTVEKKEGIHCSLLIEVPANEIDSVVSKEINRTAKTIKMDGFRPGKVPAGMVKKKYGEQIRMEVISDLIPQKYSKAIQDEKLAVAGIEVELKENKEGQPLKFVANLELFPEFEVTGFEKIEVQKPVVELTDKEVKQMIENLRKQFATFSEVDKVVEKDDKVTIDFVGKKDGEAFEGGTANDIDVIIGSGQMIPGFEDGIIGMKKGEQKTITVTFPQDYQNKDLAEAETTFDITVKKIQQAELPEVNDEFVKKFGVKGGVDTFENEIKENMQRELKFILQRKVKDQVFKGLREIAEFETPKSLIKREIDAAKQNLLKQMGGAKGFDVNQLPDNLFEANAKQKVETSLILDSIMNSQEFKAEEAEVESLLDELVQAYEEPEKTKEQIKKNDKEIANLKALVIENKLTDWVLEQAKVTEKTEDFFEVIKENMQAQQAGF
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: Y904_LACJO
Sequence: MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKSGGPDPSGNPTLRMVMDKARAANMPKTNIERAIKKAEGNSDEHYDEITYEGYAPGGVAVLVEALTDNKNRTASDVRVAFTRNGGSLGATGSVAYMFDRKGYLVIDRSTTDADEDQVLLDVMDAGGDDLETSDDAFEIYTDPKQFTAVRDALEKAGYKLANAELTMIPQNTTPVPADKKEQFAHLIDALEDNDDVSNVYTAAADDDE
What are the official names of this protein?
Probable transcriptional regulatory protein LJ_0904.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SKI8_CHICK
Sequence: MTTQYGILFKQEQAHDDAIWSVAWGKNKKNGSETVISGSLDDLVKVWKWNDEKLDLQWTLEGHQLGVVSVDISHTGSIAASSSLDAHIRLWDLETGKQIKSIDAGPVDAWSLAFSPDSQFLATGSHVGKVNIFGVETGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHGSWVLNVAFCPDDTHFVSSSSDKSVKVWDAGTRTCVHTFFDHQDQVWGVKYNGSGSKIVSVGDDQEIHIYDCPV
What are the official names of this protein?
SKI8 subunit of superkiller complex protein, WD repeat-containing protein 61.
Protein: MRAY_SYNS3
Sequence: MKERDVNDAQETPPPLEGKVSAGVLAVVVYAAAFASDRWIPNSLLSLPLLIATLIAAIVTWWGVPKLRGLKLGQVIREEGPQAHLTKSGTPTMGGLLVVPVGVIVGGLISWSGQAAEQLLAVAFITLAYMVVGGIDDWRSLTKHTNTGLTPRGKLLLQALAAVIFLIWAGMRGWISGDVALPFDINLPLNWLIWPLAVFVFLAESNATNLTDGLDGLAAGCGALVFTGMALQLTLRGNSGDPSLAGFCMAMAGCWIGFLVHNRNPAKVFMGDTGSLAMGGALTAVALLTNSLWPLLIMGGIFLAESLSVIIQVWVFKATKGADGIGRRVFRMSPLHHHFELGGTPEQLVVPGFWLATVFLVLIGIFFKPN
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YM009_YEAST
Sequence: MRMEAQVVAVSPHGVVLPLGVAKVMEVHPLGAVLAAVPQLGAAKVLVLLLLGVVLQPGVTNQVGAVHPLGRRVVNLMVPCLLGVVPVIGQPTAGLPPGEEITIIKVQEMAELLHGVTKTMEIGLLGTTKEISQTMVVTVHGEVINHQKENQYHPRRNQ
What are the official names of this protein?
Putative uncharacterized protein YML009W-B.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PSD_PSEPG
Sequence: MKSRLFIISQYLLPHHLLSRLAGCVAECRARWFKNAFTAWFAKRYQVNMSEALVEDLSAYEHFNAFFTRALKPGARPLDETPGAILCPADGAVSQLGPIEHGRIFQAKGHGFSAQELLGGDPAMAAPFMGGEFATIYLSPKDYHRVHMPLAGTLREMVYVPGRLFSVNQTTAENVPELFARNERVVCLFDTERGPMAVVLVGAMIVASIETVWAGLVTPPKRELKTFRYDEASRAPIHLEKGAELGRFKLGSTAIVLFGPEQVRWAESLGAGSAVRMGQLLAEPVQA
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: VP7_ROTRH
Sequence: MYGIEYTTVLTFLISLILLNYILKSLTRMMDFIIYRFLFIVVILSPLLKAQNYGINLPITGSMDTAYANSTQEETFLTSTLCLYYPTEAATEINDNSWKDTLSQLFLTKGWPTGSVYFKEYTDIASFSVDPQLYCDYNVVLMKYDATLQLDMSELADLILNEWLCNPMDITLYYYQQTDEANKWISMGSSCTIKVCPLNTQTLGIGCLTTDTATFEEVATAEKLVITDVVDGVNHKLDVTTATCTIRNCKKLGPRENVAVIQVGGSDVLDITADPTTAPQTERMMRINWKKWWQVFYTVVDYVNQIIQAMSKRSRSLNSAAFYYRI
What is the function of this protein?
Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved.  Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors.  Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion (PubMed:25211455, PubMed:21849465).  This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7 (PubMed:25211455, PubMed:21849465, PubMed:21157433).
What are the official names of this protein?
Outer capsid glycoprotein VP7.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP7 family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum lumen. Note=The outer layer contains 780 copies of VP7, grouped as 260 trimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles.
Protein: Y3410_MYCTU
Sequence: MVEIGMGRTARRTYELSEISIVPSRRTRSSKDVSTAWQLDAYRFEIPVVAHPTDALVSPEFAIELGRLGGLGVLNGEGLIGRHLDVEAKIAQLLEAAAADPEPSTAIRLLQELHAAPLNPDLLGAAVARIREAGVTTAVRVSPQNAQWLTPVLVAAGIDLLVIQGTIVSAERVASDGEPLNLKTFISELDIPVVAGGVLDHRTALHLMRTGAAGVIVGYGSTQGVTTTDEVLGISVPMATAIADAAAARRDYLDETGGRYVHVLADGDIHTSGELAKAIACGADAVVLGTPLAESAEALGEGWFWPAAAAHPSLPRGALLQIAVGERPPLARVLGGPSDDPFGGLNLVGGLRRSMAKAGYCDLKEFQKVGLTVGG
What is the function of this protein?
Has no inosine-5'-monophosphate dehydrogenase activity.
What are the official names of this protein?
Uncharacterized oxidoreductase Rv3410c.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.
Protein: UBIA_YERPA
Sequence: MKGSTVHTKWQAYCRLMRIDKPIGSLLLLWPTLWALWLAGRGIPEAKILVVFVLGVFFMRAAGCVVNDYADRHIDGFVKRTASRPLPSGTISEKESKILFVVLILLSFGLVLTLNSMTIWLSLAALALAWIYPFMKRVTHLPQVVLGAAFGWSIPMGFAAVSESLPLVCWLLLLANICWTVAYDTQYAMVDRDDDLRIGVKSTAILFGQHDKLIIGLLQLATLLLMVAIGWLMNLGGAFYWSILLAGALFTHQQKMIAQREREPCFRAFLNNNYVGLVLFLGILISYW
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CTBL1_HUMAN
Sequence: MDVGELLSYQPNRGTKRPRDDEEEEQKMRRKQTGTRERGRYREEEMTVVEEADDDKKRLLQIIDRDGEEEEEEEEPLDESSVKKMILTFEKRSYKNQELRIKFPDNPEKFMESELDLNDIIQEMHVVATMPDLYHLLVELNAVQSLLGLLGHDNTDVSIAVVDLLQELTDIDTLHESEEGAEVLIDALVDGQVVALLVQNLERLDESVKEEADGVHNTLAIVENMAEFRPEMCTEGAQQGLLQWLLKRLKAKMPFDANKLYCSEVLAILLQDNDENRELLGELDGIDVLLQQLSVFKRHNPSTAEEQEMMENLFDSLCSCLMLSSNRERFLKGEGLQLMNLMLREKKISRSSALKVLDHAMIGPEGTDNCHKFVDILGLRTIFPLFMKSPRKIKKVGTTEKEHEEHVCSILASLLRNLRGQQRTRLLNKFTENDSEKVDRLMELHFKYLGAMQVADKKIEGEKHDMVRRGEIIDNDTEEEFYLRRLDAGLFVLQHICYIMAEICNANVPQIRQRVHQILNMRGSSIKIVRHIIKEYAENIGDGRSPEFRENEQKRILGLLENF
What is the function of this protein?
Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing.  Participates in AID/AICDA-mediated somatic hypermutation (SHM) and class-switch recombination (CSR), 2 processes resulting in the production of high-affinity, mutated isotype-switched antibodies (PubMed:32484799).
What are the official names of this protein?
Beta-catenin-like protein 1, Nuclear-associated protein, NAP, Testis development protein NYD-SP19.
What are the subcellular locations of this protein?
[Isoform 1]: Nucleus. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
Protein: GLMU_DECAR
Sequence: MNIVILAAGQGKRMHSNLPKVLHPIAGKPLAQHVIDTARQLSPEKLIVVYGHGGEVVRSTLAAPDLSWAEQAQQLGTGHAVAQALSELGSAAQTLVLYGDVPLTTVATLKRLLQAGKDALSVLTVDLANPSGYGRIVRDGAGNMISIVEEKDASAEQKAIREVNTGIMAVPTARLADWLGKLKNDNAQGEYYLTDIIALAVAEGMPVRTAQPEGEWEVLGVNSKVQLAELERQHQLNLAGELLVAGVRLADPARIDIRGELTHGRDVAIDVGCVFEGKVELADAVEVGPYCVLKNVKVGAGTRIAAFCHFEDAVIGPDGVLGPYARLRPGTELGPEVHIGNFVEVKKSIIGAQSKANHLAYIGDAEIGQRVNVGAGTITCNYDGANKFKTVIEDDVFIGSDTQLVAPVTVGRGATLGAGTTLTKDAPPDALTFSRPRQMTLPGWERPKKVKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDI11_ORYSJ
Sequence: MAISKAWISLLLALAVVLSAPAARAEEAAAAEEGGDAAAEAVLTLDADGFDEAVAKHPFMVVEFYAPWCGHCKKLAPEYEKAAQELSKHDPPIVLAKVDANDEKNKPLATKYEIQGFPTLKIFRNQGKNIQEYKGPREAEGIVEYLKKQVGPASKEIKSPEDATNLIDDKKIYIVGIFSELSGTEYTNFIEVAEKLRSDYDFGHTLHANHLPRGDAAVERPLVRLFKPFDELVVDSKDFDVTALEKFIDASSTPKVVTFDKNPDNHPYLLKFFQSSAAKAMLFLNFSTGPFESFKSVYYGAAEEFKDKEIKFLIGDIEASQGAFQYFGLREDQVPLIIIQDGESKKFLKAHVEPDQIVSWLKEYFDGKLSPFRKSEPIPEVNDEPVKVVVADNVHDFVFKSGKNVLVEFYAPWCGHCKKLAPILDEAATTLKSDKDVVIAKMDATANDVPSEFDVQGYPTLYFVTPSGKMVPYESGRTADEIVDFIKKNKETAGQAKEKAESAPAEPLKDEL
What is the function of this protein?
Probable protein disulfide isomerase that plays an essential role in the segregation of proglutelin and prolamin polypeptides within the ER lumen of endosperm.  Required to retain proglutelin in the cisternal ER lumen until ER export and, thereby, indirectly prevents heterotypic interactions with prolamin polypeptides.
What are the official names of this protein?
Protein disulfide isomerase-like 1-1, OsPDIL1-1, Endosperm storage protein 2, Protein ESP2.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Note=Distributed asymmetrically within the cortical endoplasmic reticulum (ER) and largely restricted to the cisternal ER.