PharMolix/UniProtQA huggingface dataset:
Protein: XYLA_ASPNC
Sequence: MYFSSFLALGALVQAAAATYFAPNSTGLRIQHGFETILIQPFGYDGFRVRAWPFRPPSGNEISFIYDPPIEGYEDTAHGMSYDTATTGTEPRTLRNGNIILRTTGWGGTTAGYRLSFYRVNDDGSETLLTNEYAPLKSLNPRYYYWPGPGAEFSAEFSFSATPDEQIYGTGTQQDHMINKKGSVIDMVNFNSYIPTPVFMSNKGYAFIWNMPAEGRMEFGTLRTRFTAASTTLVDYVIVAAQPGDYDTLQQRISALTGRAPAPPDFSLGYIQSKLRYENQTEVELLAQNFHDRNIPVSMIVIDYQSWAHQGDWALDPRLWPNVAQMSARVKNLTGAEMMASLWPSVADDSVNYAALQANGLLSATRDGPGTTDSWNGSYIRNYDSTNPSARKFLWSMLKKNYYDKGIKNFWIDQADGGALGEAYENNGQSTYIESIPFTLPNVNYAAGTQLSVGKLYPWAHQQAIEEGFRNATDTKEGSACDHVSLSRSGYIGSQRFCSMIWSGDTTSVWDTLAVQVASGLSAAATGWGWWTVDAGGFEVDSTVWWSGNIDTPEYRELYVRWLAWTTFLPFMRTHGSRTCYFQDAYTCANEPWSYGASNTPIIVSYIHLRYQLGAYLKSIFNQFHLTGRSIMRPLYMDFEKTDPKISQLVSSNSNYTTQQYMFGPRLLVSPVTLPNVTEWPVYLPQTGQNNTKPWTYWWTNETYAGGQVVKVPAPLQHIPVFHLGSREELLSGNVF
What is the function of this protein?
Catalyzes the liberation of alpha-xylose from the non-reducing terminal glucose of xyloglucan oligosaccharides.
What are the official names of this protein?
Alpha-xylosidase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 31 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNH2_STAAT
Sequence: MTLTIKEVTQLINAVNTIEELENHECFLDERKGVQNAIARRRKALEKEQALKEKYVEMTYFENEILKEHPNAIICGIDEVGRGPLAGPVVACATILNSNHNYLGLDDSKKVPVTKRLELNEALKNEVTAFAYGIATAEEIDEFNIYKATQIAMQRAIDGLSVQPTHLLIDAMTLDNALPQVSLIKGDARSVSIAAASIMAKVFRDDYMTQLSKDYPEYGFEKNAGYGTKQHLLAIDDIGIMKEHRKSFEPIKSLL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG015_MONPV
Sequence: MESVDFMAVDEQFHDDLDLWSLSLVDDYKKHGLGVDCYVLEPVVDRKIFDRFLLEPICDPVDVLYDYFRIHRDNIDQYIVDRLFAYITYKDIISALVSKNYMEDIFSIIIKNCNSVQDLLLYYLSNAYVEIDIVDLMVDHGAVIYKIECLNAYFRGICKKESSVVEFILNCGIPDENDVKLDLYKIIQYTRGFLVDEPTVLEIYKLCIPYIEDINQLDAGGRTLLYRAIYAGYIDLVSWLLENGANVNAVMSNGYTCLDVAVDRGSVIARREAHLKILEILLREPLSIDCIKLAILNNTIENHDVIKLCIKYFMMVDYSLCNVYASSLFDYIIDCKQELEYIRQMKIHNTTMYELIYNRDKNKHASHILHRYSKHPVLTQCITKGFKIYTEVTEQVTKALNRRALIDEIINNVSTDDNLLSKLPLEIRDLIVSQAVI
What is the function of this protein?
May be involved in virus-host protein interaction through the ankyrin repeats.
What are the official names of this protein?
Ankyrin repeat domain-containing protein OPG015.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG015 family.
Protein: HTPG_HAES1
Sequence: MSTNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSAPELYEGDGDLKVRISFDAEKGTLTISDNGIGMTREQVIDHLGTIAKSGTKEFLAALGQEQAKDSQLIGQFGVGFYSAFIVADKVTVKTRAAGEPIDKAVLWESAGEGEYSVADIEKKERGTEITLHLREEEKEFANEWRVREIIGKYSDHIGLPVEILAKEYDEEGKETGIKWEKINKAQALWTRSKGEISDEEYKEFYKHLSHDFADPLLWTHNKVEGNQEYTSLLYVPSKAPWDLFNREHKHGLKLYVQRVFIMDDAEQFMPNYLRFMRGLIDSNDLPLNVSREILQDNKVTAALRKALTKRSLQMLEKLAKDDEEKYLQFWKEFGLVLKEGPSEDFANKENIAKLLRFASSKNDSSEQTVSLEDYVARMKEGQKAIYYITADSYIAAKNSPHLELFNKKDIEVLLLSDRIDEWMLSYLTEFDGKQLQPITKADLDLGDLADKEQEEQKEQDKTFSSFIERVKTLLGERVKDVRLTHRLTDTPAVVSTDNDQMTTQMAKLFAAAGQPVPEVKYTFELNPEHHLVKKVADLADEDEFANWIELLLEQAMLAERGSLENPTAFIKRVNSLLS
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAT3_ARATH
Sequence: MVETGHHHQHPPAPAAAGHPPVPSMAMARNMGTTWPPAEQLHHLQYCIHSNPSWHETVVLAFQHYIVMLGTTVLIANTLVSPMGGDPGDKARVIQTILFMSGINTLLQTLIGTRLPTVMGVSFAYVLPVLSIIRDYNNGQFDSEKQRFRHTMRTVQGSLIISSFVNIIIGYGQAWGNLIRIFSPIIVVPVVSVVSLGLFLRGFPLLANCVEIGLPMLILLIITQQYLKHAFSRISMILERYALLVCLAIIWAFAAILTVSGAYNNVSTATKQSCRTDRAFLMSSAPWIRIPYPFQWGTPIFKASHVFGMFGAAIVASAESTGVFFAASRLAGATAPPAHVVSRSIGLQGIGVLLEGIFGSITGNTASVENVGLLGLTRIGSRRVVQVSTFFMIFFSIFGKFGAFFASIPLPIFAGVYCILLGIVVAVGISFIQFTDTNSMRNMYVIGVSLFLSLSIAQYFLANTSRAGYGPVRTAGGWFNDILNTIFASAPLVATILATILDNTLEARHASDDARGIPWWKPFQHRNGDGRNDEFYSMPLRINELMPTRFL
What are the official names of this protein?
Nucleobase-ascorbate transporter 3, AtNAT3.
What is the protein family that this protein belongs to?
Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BLIP_STRCL
Sequence: MRTVGIGAGVRRLGRAVVMAAAVGGLVLGSAGASNAAGVMTGAKFTQIQFGMTRQQVLDIAGAENCETGGSFGDSIHCRGHAAGDYYAYATFGFTSAAADAKVDSKSQEKLLAPSAPTLTLAKFNQVTVGMTRAQVLATVGQGSCTTWSEYYPAYPSTAGVTLSLSCFDVDGYSSTGFYRGSAHLWFTDGVLQGKRQWDLV
What is the function of this protein?
Inhibits a wide variety of beta lactamases.
What are the official names of this protein?
Beta-lactamase inhibitory protein, BLIP.
What are the subcellular locations of this protein?
Secreted.
Protein: Y838_STAAS
Sequence: MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTLLAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNYKDHANELNHEVEKLYVFTKAASSLTGDNATIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENVNIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMQPPKFLQPGDEVKVTIDNIGTLTTYIAK
What are the official names of this protein?
Uncharacterized protein SAS0838.
What is the protein family that this protein belongs to?
Belongs to the FAH family.
Protein: ACOC_CUPNH
Sequence: MATEISPTIIPIVMPKWGLSMKEGTVNAWLVDEGTEITVGLPILDVETDKIANAVEAPDAGTLRRKVAQAGDVLPVKALLGVLAPAEVSDAQIDDYVAAYETPADDAGEEDAAAAYQFADVDGIRVRYARKGGGAETVLFIHGFGGDLDNWLFNLDPLADAYTVVALDLPGHGQSSPRLAGTTLAQMAGFVARFMDETGIEAAHVVGHSMGGGVAAQLAVDAPQRVLSVALVSPVGFGDAVNSGYTEGFVSAQSRRELKPVVELLFADAGLVSRQMLDDLLRYKRLDGVTEALTALGQGLFGGGRQSEQPGQRLANSGKRVLVVWGGQDQIIPAAHAEAAPPGATVKVFADAGHMSQMEKANDFNALLKKHLGG
What is the function of this protein?
Dihydrolipoamide acetyltransferase involved in acetoin catabolism.
What are the official names of this protein?
Dihydrolipoyllysine-residue acetyltransferase component of acetoin cleaving system, Acetoin dehydrogenase E2 component, Dihydrolipoamide acetyltransferase component of acetoin cleaving system, Fast-migrating protein, FMP.
Protein: WHIA_LEUCK
Sequence: MSYAADVKKELTGLRVHDGNAKAELSALMRMNGVSTLGIDQTVSVKTENAAIARRIYTLLKQNYTQIEVEVTVAEHNYMSQHKSYGVLLKNKVSDVLTDLGVDPFGLHPDIPDRILNQVDKRRSFLRGAFLAAGSVNSPEKANYHLEIFTTHEELAETLRLMMAEFGLPAKIIDRSGGYVIYIKRAEKIVDFLSTIGATQTMLRFEDIRMMRDMRNSVNRMTNAELANIQKTADAANKQVQQILFIANEIGDLDLLPKKLRDIAKARLEHPDDSLAELGDRLEISKSGANHRMRKLKALEDMINAGVTYDLNKL
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: RL3_CLONN
Sequence: MKKAIIGRKIGMTQIFDENGKVIPVTVVEAGPCAVLQKKTEEKDGYNAIQVGFEDIREKLANKPKKGHFAKAGVSLKRIVREFRLENIDEYEVGTEIKADVFAAGDKVDVTGVSKGKGFQGTIKRWNFHRGPMAHGSKYHRAVGSMGAASDPSRTFKNKKMPGHMGNKKSTILNIEVVKVMADKNVLLIKGGIPGPNKGYVVIKDTVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: BIOY_PYRHO
Sequence: MKAKEVSLVALFVALTSVGAQISVSIGPVPLTLQVFFVILAGLVLGPKLGFLSILIYDILGALGIPVFAGFSGGIAHILGPTGGYIIAFPIATFIAGLGRGKVRYLTSLMGLLVIYLIGWMWLARFVGFNKAFILGVLPFIVPDIVKAATAVIIAERLQGNT
What is the function of this protein?
Probable biotin transporter.
What are the official names of this protein?
Probable biotin transporter BioY.
What is the protein family that this protein belongs to?
Belongs to the BioY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LIPA_PLAYO
Sequence: MNFLVLFFSYSIFVLPYSILVYGISKDRKCCEYGNSVDSSKILYIAGSVRKRRKTFEKKINVSNFEREGNANGYKHIDNKGIYATKQNLEFDEARNKEANENNKNDATTVNRKIIIESENKNNHNNQEQNIKDCYTNENAQNDEKNKKVKIPKVGNAMPEKKPDWFHVPAPNGEKYKKLKSDLGKLKLHTVCEEAQCPNIGECWNIGTATIMLLGDTCTRGCKFCSIKTSSKPPPPDINEPFNTAKAICEWDINYIVITSVDRDDLPDGGADHFAKTVELIKFSKPSILIECLVSDFQGNIDSIKRLALSGLDVYAHNIETVKRLQKYVRDKRANYEQSLYVLKKAKEINPNLYTKTSIMLGLGETQDEVLQTMKDARSNDIDVITFGQYLRPTKNHLNVVEYISPQMFNYYKDVGLKMGFKYIASGPLVRSSYMAGEYFMKNMVEKGRNQKNQQIKPVELKLVTELDKLTECIQKEIKHREISVFIQVHAFLVNVFVLVRA
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, apicoplast, Lipoate synthase, LS, Lip-syn, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Plastid, apicoplast.
Protein: DEXH4_ARATH
Sequence: MAPTKKPQKNKQSKNEIASSLIPNSGHKKPSKAPKLLISPENEDRLRRLLLNFRRTPSPVTATLSVTQKRKKLNNLYENLSCEGFLDNQIELVLSSLRDGATLETALDWLCLNLPSHELPVNFSNGASRFPSTGRSVAVISKSKKDWNVSAESSVQEVKEVPESEVLVRVKSKRDEEEEDSLSSCQPSQADWIHQYMKRLEEEELESSDDERDKVSGPRSFEVIAKEYCVERYNAIKAKRKGDKSGQSQAGLAICKLKEEMNALGPSEAILESEFQRDRQDCEGAREKEVASSVLDDVHESVNADAFFFQLFDDLTLDTNPVGSCKSEEQESVVSNDSLDDLDLGDLFDEDVPPYVPSPHELLELQKKEIMRELCNEKHLTKLNGIWKKGEAQKIPKALLHQLCQRSGWIAPKFNKVTGEGRNFSYTTSVMRKSSGFGKSRQAGGLVTIQLPHQVEDFESIQDAQNRVAAFALHKLFSDLPVHFAITEPYASLVLIWKQEESLGITSREEQRREKFVESLLEADNFSLTTTSRGIHSALPMVDSCVKENDDLDVVKSNHRARRNSSMAAECSSLKQKQENKKKMQKYKDMLKTRAALPISEVKKDILQKLKEKDVLVVCGETGSGKTTQVPQFILDDMIDSGHGGYCNIICTQPRAITVAQRVADERCEPPPGFDNSVVAYQVRHQNARSDKTRLLFCTTGILLRKLVGDTTLKDVTHIIVDEVHERSLMGDFLLIILKSLIEKQSWDNALPKLKVILMSATVDAHQFSRYFGQCPIITAQGRTHPVTTYFLEDIYERTKYLLASDSPAALSSDTSITDKLGSVNVPRGKKNLMLAGWGDSYLVSEDSLNTSYDSIKYIASAVVDYDLLEELICHIDDTCEEGAILVFLPGMSEINMLLNRLAASYRFRGASGDWLLPLHSSIASTEQKKVFLRPPKGIRKVIIATNIAETSITIEDVVYVIDSGKHKENRYNPHKKLSSMVEDWVSKANARQRMGRAGRVKPGHCFSLYTRHRFEKLMRPYQVPEMLRVPLVELCLHIKLLGLGQIKPFLSKALEPPSESAINSAILLLHKVGALEGDEELTPLGHHLAKLPVDLLIGKMLLYGGIFGCLSPILSIAAFLSCCKSPFVYAKDEQNVDRVKLALLSDKLESSSNLNNNDRQSDHLLMVVAYEKWVRILHEQGFKAAESFCESKFLNSSVMRMMRERRVEFGMLLADIGLINLPKGKGRRKENFDVWFSDKTQPFNMYSQEPEVVKAILCAGLCPNIAEGLVNRLTKPAEETQRYAVWHDGKREVHIHRNSINKNCKAFQYPFIVFLEKLETKKVVYLQDTTVVSPFSILLFGGSINVHHQSGSVTIDGWLKLTAPAQTAVLFKELRLTLHSILKDLIRKPEKSGIVHNEVVKSMVHLLIEEGKPQHT
What are the official names of this protein?
DExH-box ATP-dependent RNA helicase DExH4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the DExH box helicase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TECTA_CHICK
Sequence: MNTRSLLSAWAALLVVTVRHRAHAMASLYPFWPNDTKTPKVDDGSSSEIKLSVPFIFFRSPYRTVYVNNNGVISFNSLVSQFTPEAFPLADGRAFVAPFCGDVANGIRGEIYYRESTNPELLGESSKDIRKYFKDMASFSASWVFIVTWEEVQFYGGSSTTPVNTFQAVLITDGVSSFAIFNYQEISWTTGTASGGDPLTGLGGVMAQAGFNGGNISNFFSIPGSRTPDIVNIEQTTNVNIPGRWAFKIDGREIDPANLSLRGQFLHQGEIFWENSNCSTKCRCLDFNNEIFCQEMLAPFETVEPKIKFFQCVPVETACVVFGDPHYHTFDGFLFHFQGSCSYLLARQCWPGSQLPYFNVEAKNERGGSSVSWAEDIFVEVYRHKIVLPKGGFGKAKVDDLVVSLGAIKVYQSGLSTALETDFGLLVTYDGQHYASVSVPGTYINGTCGLCGNYNKDPEDDALRSDGRLASSVPELGESWRVPHPERKCSPGCVENCSVCDASRILYSPICGFSQECGAWSVLVATAFVHSCVYDLCSARRTHRLCQAIQVTLRCCQGLGIRWENGVPDGMRGGLAVPGHSHYSGCASGCPATCSDLTAPLRCTAPCPEGCECDDGHVLSARPLHSLCRSGCVVDGRSRCREVFWATADCTAECQCEDGGEAKCFNTSCPEGEVCTIEDGYRGCYPKREGLCSVGQNQVLRTFDGVTFPYPLEHSYTLLKTCMEKPDFIEVDISQKKPDTLPMAGRVVRIQVVGQEVKVGGASLSEVKVNGYDVDLPYFHPSGHLEIYRTDNGTVTESEGLLSIGYYDSGLLEIRLSTAYFNCTGGLCGFFNGNDSDEFCTPKAKCTDNLELFLESWTTFDEICNGECGDLLKACNNDSELLKTYRSRSNCAIINDPTNSSFLECHNVSIVSAYYRTCLFRLCQSGGNQSELCSAVARYASACKNSEVDVGQWRSHSFCPLACPENSHFEECMSCVETCETLATGCCMDTCTEGCQCDEGFALRSPCVPRGECGCNFEGHELATNQTFWMDISCHLLCYCNGSDNSVYCENVLQDDEYYCHVRTDASCIVSGYGHYLTFDGFSFDFQSSCALVLCTTIHGACERSDTFPTFTVTVTAKNEDRDTSLACVVKQVEVEVFNYYIVIHRAYKYTVMINNERLYLPLKLGQGKVNIFAFGFHIVVETDFGLKVVYDWKTFLSVTIPRSFQNLTYGLCGRYNGNPDDDLVAAGGTPRFGVTDFVQSWAKRDTFCRVGSGDRCPACGKVEGFWKPQQLCSLIPSQSGVFAKCHSKINPSYFYKNCLFDTVVDGGAMARRVADWLQNYASTCQTQGIAIIGWRNFTSCSVSCPPNSHYESCVSLCQPRCAAIRLKSDCGHYCVEGCQCDPGYVLNGKSCILPQNCGCYSDGKYYEPKQLFWNGDCTRRCARFRRNLIQCDPRHCKSDEECASRNGVRGCFSTRSSFCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQRLADFSFQLIINFDKWSSPNLTIISVYIYINEEQILISDRSTVKVNGSLVSIPFVTGLSTKIYSQEGFLVIDSGPDIHIRYNGFNVIKITIGDRLQNKVCGLCGNFNGDPADDYATLRGKPVVSSVVLAQSWKTNGMQKSCNELQYSQYAASCDNVQIQKLQSDSYCLKLTDMKGFFQPCYGLLDPLPFYESCFLDGCYNRKQVQLCGSLAAYGEACRTFGILGTEWIEKENCSGVVEDPCAGADCPNRTCELDDGGELCGCIEPPPYGNTTHDIIDAEVTCKAAQMEVSISKCKLFQLGFEREGVRVNDRHCPGIEGEDFISFQINNTKGNCGNLVQSNSTHIVYKNTVWIESANNTGNIITRDRTINVEVFCAYELDIKISLDSVVRPMLSVINLTVPTQEGSFTTKMALYKNSSYKHPYRQGEVVLTTRDVLYVGVFVVGADSNHLILMLNKCYATPSRDSNDKLRYFIIEGGCQNLKDNTIGIEENGVSLTCRFHVTVFKFIGDYDEVHLHCAVSLCDSEKYSCKINCPQHRRSASAFAQEAHEQILSVGPIRRKRSDWCEDNGGCEQICTSQADGPLCSCVTGTLQGDGKSCMASSSSADIRAQASLLVAAQLWLWAALHDPTS
What is the function of this protein?
One of the major non-collagenous components of the tectorial membrane.  The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells.  Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals.
What are the official names of this protein?
Alpha-tectorin.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor; Extracellular side. Secreted, extracellular space, extracellular matrix. Note=Found in the non- collagenous matrix of the tectorial membrane.
Protein: TOP1_STAAB
Sequence: MADNLVIVESPAKAKTIEKYLGKKYKVIASMGHVRDLPRSQMGVDTEDNYEPKYITIRGKGPVVKELKKHAKKAKNVFLASDPDREGEAIAWHLSKILELEDSKENRVVFNEITKDAVKESFKNPREIEMNLVDAQQARRILDRLVGYNISPVLWKKVKKGLSAGRVQSVALRLVIDRENEIRNFKPEEYWIIEGEFRYKKSKFNAKFLHYKNKPFKLKTKKDIEKITAALDGDQFEITNVTKKEKTRNPANPFTTSTLQQEAARKLNFKARKTMMVAQQLYEGIDLKKQGTIGLITYMRTDSTRISDTAKAEAKQYITDKYGESYTSKRKASGKQGDQDAHEAIRPSSTMRTPDDMKSFLTKDQYRLYKLIWERFVASQMAPAILDTVSLDITQGDIKFRANGQTIKFKGFMTLYVETKDDIDSEKENKLPKLEQGDKVTATQIEPAQHYTQPPPRYTEARLVKTLEELKIGRPSTYAPTIDTIQKRNYVKLESKRFVPTELGEIVHEQVKEYFPEIIDVEFTVNMETLLDKIAEGDITWRKVIDGFFSSFKQDVERAEEEMEKIEIKDEPAGEDCEVCGSPMVIKMGRYGKFMACSNFPDCRNTKAIVKSIGVKCPKCNDGDVVERKSKKNRVFYGCSKYPECDFISWDKPIGRDCPKCNQYLVENKKGKTTQVICSNCDYKEAAQK
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I, Omega-protein, Relaxing enzyme, Swivelase, Untwisting enzyme.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: HEM2_PROFF
Sequence: MADISIDPIVQRPRRLRRTPAIRRMVAETRLDPADLVLPMFAVEGLTEPREIATMPGVWQHTKESLQKAVHDAADAGVGAVMLFGTPLERDPIGSQAWNPHGILANAVRWAVEAEPELPVIADVCLDEFTDHGHCGVLAPDGTVDNDATLPLYAKMSVVLADAGAAMLGPSGMMDGQIAVIRKALDDAGHTDTVLMAYSAKYASGFFGPFREAVDSQLKGDRRAYQQDPANAIESLREIELDLEQGADFVMVKPAMAYLDVLAAARAISNVPVAAYVVSGEYSMIEFAAKAGALDRKRCIMEALTSVKRAGASTIVTYWATEVAIWLNEVRS
What is the function of this protein?
Catalyzes an early step in the biosynthesis of tetrapyrroles.  Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).
What are the official names of this protein?
Delta-aminolevulinic acid dehydratase, ALAD, ALADH, Porphobilinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the ALAD family.
Protein: GSA_CALS8
Sequence: MRFDKSKEIFDNTKRYIPGGVNSPVRAFKNLSITPPVISKGKGCRIFDIDGNEYIDFVLSWGAMILGHCDPDVVNSIKEVVEDQIAFGAPTEIEYKMAKLVCETAQVDMVRFVNSGTEATMTAIRLAKGYTGKKKIVKFAGCYHGHHDIFLKEAGSAVAELRLKGIDEDIVQNTIVVEYNNLDSIEKAFKENKDEISAVIIEPVAGNMGVVPAKKEFLQALREICDLHGSLLIFDEVITGFRLSLKGARALYNVEPDLVTFGKIIGGGLPCGAVGGKKEIMQCLAPQGNVFQAGTMSGNPIVMSAGYATIKKLKENPDIYTYLELLAQKLEGNLAKVFSSSNLTFCINRVGSMLTVFFGVEKVENFEMAKKSNLSMFKKFAEYMITNGIYIPSSQFEAMFLSSAHTESDIERFAEVAEGFAKFVKKP
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_SALSV
Sequence: MTTLLNPYFGEFGGMYVPQILMPALNQLEEAFVSAQKDPEFQAQFADLLKNYAGRPTALTKCQNITAGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHALAHALKMMREQPEKEQLLVVNLSGRGDKDIFTVHDILKARGEI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: RU17_DICDI
Sequence: MAFLPPNLKIMFNPRHPPPFLPPPPPSNLPPYTGLRDYLSIFTDPSNEEPFKKEHIENLEEKREKKRKLKISENDERISKSLKAWDPYSNSETTGDPYKTIFVSRISYKTTQQKLEFEFGQFGPIKSLFLVKDSNNPEKHTGYAFIEFERERDMKAAYKQADGMKIDDRRIVVDIERGRVIKNWKPRKFGGGLGNTRAGGVDVNQTFSGREMSESREKEKEREKEKEKEKERMEKMKKRDGGLSSNGNRSNGISSGSGGSGGDRGDRGDRDRGDRGDRSDRSDRDRERGRGDRDHRGSGGERERERDQRDRGGDRGGDRGDRSDRGRSDRGDRGDRSDRGRDDRERGRDDRGDRGRDDRRGGSDRDRDRGSRDDRGDRDDRSDRGRDDRRGGSDRDHRIDERRRDQRDYGSISDAHFDHFQYQPQQHHHHQQNHQSHHNQPHPERVNRDYSMISNENGF
What is the function of this protein?
Mediates the splicing of pre-mRNA by binding to the stem loop I region of U1-snRNA.
What are the official names of this protein?
U1 small nuclear ribonucleoprotein 70 kDa, U1 snRNP 70 kDa, U1-70K, snRNP70.
What are the subcellular locations of this protein?
Nucleus.
Protein: JZT27_CHIGU
Sequence: MRVLFIIAVLALISVGCYASEMKDRSSRNEVLSAIFAIEEPQERDCLGLFWICNYMDDKCCPGYKCERSSPWCKIDIWG
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U24-theraphotoxin-Cg1a, U24-TRTX-Cg1a, Jingzhaotoxin-27, JZTX-27, Peptide F2-36.12.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 35 (Jztx-27) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TSAD_NOSS1
Sequence: MTTVLAIETSCDETAVAIVNNRQVLSSIIASQISVHQQYGGVVPEVASRAHLETINGAIAQAMDQAQLGWDKIDAIAATCAPGLVGALLVGLTAAKTLAILHNKPFLGVHHLEGHIYATYLSEPTLDPPFLSLLVSGGHTSLIYVKECGRYESLGETRDDAAGEAFDKVARLLKLGYPGGPVIDKLAQTGNPQAFALPEGKVSLPGGGYHPYDGSFSGLKTAVLRLVQQLEKDGDSLPLEDIAASFQATVAKALTKRAIACALDYGLDTIAVGGGVAANSGLRQHLQAATAANNLRVLFPPLKFCTDNAAMIACAAVDHLSRGHTSPITLGVESRLSLSQVMKLYQ
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROQ_THEMA
Sequence: MKVLVVNGPNLNMLGKRDKNIYGNFSHEDLVKMIEDWGRKNGVEVEVFQSNHEGKILDRLHRLDFDGLVINPGAFTHYSYAIRDALEIVKVPKVEVHISNIHRREEFRRRSVTAEVCDGQISGLGVYGYLLALEYIKKKLEELT
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: GALE1_PEA
Sequence: MVASSQKILVTGSAGFIGTHTVVQLLNNGFNVSIIDNFDNSVMEAVERVREVVGSNLSQNLEFTLGDLRNKDDLEKLFSKSKFDAVIHFAGLKAVGESVENPRRYFDNNLVGTINLYEVMAKHNCKKMVFSSSATVYGQPEKIPCVEDFKLQAMNPYGRTKLFLEEIARDIQKAEPEWRIVLLRYFNPVGAHESGKLGEDPRGIPNNLMPYIQQVAVGRLPELNVYGHDYPTRDGSAIRDYIHVMDLADGHIAALRKLFTSENIGCTAYNLGTGRGSSVLEMVAAFEKASGKKIALKLCPRRPGDATEVYASTAKAEKELGWKAKYGVEEMCRDQWNWAKNNPWGYSGKP
What are the official names of this protein?
UDP-glucose 4-epimerase, Galactowaldenase, UDP-galactose 4-epimerase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Protein: CKX3_ORYSJ
Sequence: MEVAMVCTRVNLLILILSLCSPYKFIQSPMDFGPLNLLPTTTTASSDFGRILFHSPSAVLKPQAPRDISLLLSFLSASPLGKVTVAARGAGHSIHGQAQALDGIVVEMSSLPSEIEFYRRGEGDVSYADVGGGIMWIELLEQSLKLGLAPRSWTDYLYLTIGGTLSNAGISGQTFKHGPQISNVLQLEVVTGRGEIVTCSPTKDAELFNAVLGGLGQFGIITRARILLQEAPQKVKWVRAFYDDFATFTKDQELLVSMPVLVDYVEGFIVLNEQSLHSSSIAFPTNVDFNPDFGTKNNPKIYYCIEFAVHDYQNKNINVEQVVEVISRQMSHIASHLYSVEVSYFDFLNRVRMEEMSLRNSGLWEVHHPWLNMFVPSAGISDFRDLLMDSISPDNFEGLILIYPLLRHKWDTNTSVVLPDSGSTDQVMYAVGILRSANPDDGCSHHCLQELLLRHRRLAGAAASGLGAKQYLAHHPTPAGWRRHFGRRWERFADRKARFDPRCILGPGQGIFPRDSSSSNGAFASYS
What is the function of this protein?
Catalyzes the oxidation of cytokinins, a family of N(6)-substituted adenine derivatives, where the substituent is an isopentenyl group (Probable).  Cytokinins are plant hormones essential for plant growth, development, and stress responses (Probable).  Exhibits specific activities toward trans-zeatin (tZ) and isopentenyladenine (iP) (PubMed:36031806).  Plays a role in lamina joint inclination (PubMed:36031806).  Regulates cell proliferation and vascular bundle number on the abaxial side of lamina joint (PubMed:36031806).
What are the official names of this protein?
Cytokinin dehydrogenase 3, Cytokinin oxidase 3, OsCKX3.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: CCPG1_HUMAN
Sequence: MSENSSDSDSSCGWTVISHEGSDIEMLNSVTPTDSCEPAPECSSLEQEELQALQIEQGESSQNGTVLMEETAYPALEETSSTIEAEEQKIPEDSIYIGTASDDSDIVTLEPPKLEEIGNQEVVIVEEAQSSEDFNMGSSSSSQYTFCQPETVFSSQPSDDESSSDETSNQPSPAFRRRRARKKTVSASESEDRLVAEQETEPSKELSKRQFSSGLNKCVILALVIAISMGFGHFYGTIQIQKRQQLVRKIHEDELNDMKDYLSQCQQEQESFIDYKSLKENLARCWTLTEAEKMSFETQKTNLATENQYLRVSLEKEEKALSSLQEELNKLREQIRILEDKGTSTELVKENQKLKQHLEEEKQKKHSFLSQRETLLTEAKMLKRELERERLVTTALRGELQQLSGSQLHGKSDSPNVYTEKKEIAILRERLTELERKLTFEQQRSDLWERLYVEAKDQNGKQGTDGKKKGGRGSHRAKNKSKETFLGSVKETFDAMKNSTKEFVRHHKEKIKQAKEAVKENLKKFSDSVKSTFRHFKDTTKNIFDEKGNKRFGATKEAAEKPRTVFSDYLHPQYKAPTENHHNRGPTMQNDGRKEKPVHFKEFRKNTNSKKCSPGHDCRENSHSFRKACSGVFDCAQQESMSLFNTVVNPIRMDEFRQIIQRYMLKELDTFCHWNELDQFINKFFLNGVFIHDQKLFTDFVNDVKDYLRNMKEYEVDNDGVFEKLDEYIYRHFFGHTFSPPYGPRSVYIKPCHYSSL
What is the function of this protein?
Acts as an assembly platform for Rho protein signaling complexes.  Limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability and its transforming activity.  Does not inhibit activity of MCF2L toward CDC42, or activity of MCF2 toward either RHOA or CDC42 (By similarity).  May be involved in cell cycle regulation.
What are the official names of this protein?
Cell cycle progression protein 1, Cell cycle progression restoration protein 8.
What is the protein family that this protein belongs to?
Belongs to the CCPG1 family.
What are the subcellular locations of this protein?
Cytoplasmic granule membrane; Single-pass type II membrane protein.