PharMolix/UniProtQA huggingface dataset:
Protein: HSLO_STAAM
Sequence: MTHDYIVKALAFDGEIRAYAALTTETVQEAQTRHYTWPTASAAMGRTMTATAMMGAMLKGDQKLTVTVDGQGPIGRIIADANAKGEVRAYVDHPQTHFPLNEQGKLDVRRAVGTNGSIIVVKDVGMKDYFSGASPIVSGELGEDFTYYYATSEQTPSSVGLGVLVNPDNTIKAAGGFIIQVMPGAKDETISKLEKAISEMTPVSKLIEQGLTPEGLLNEILGEDHVQILEKMPVQFECNCSHEKFLNAIKGLGEAEIQNMIKEDHGAEAVCHFCGNKYKYTEEELNVLLESLA
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSUD_BRADU
Sequence: MSQSKSNILWFLPTHGDGRYLGTATGGREVNFNYLRQIAQAADQLGYFGVLLPTGRSCEDSWIVASSVAPFTERLRYLVAVRPGLQSPSVAARMTATLDRITNGRLLINVVTGGDPVENKGDGIFLGHDERYEVTREFLNVYSDLLGGKAVNVEGKHIRIEDGKLLFPPVQSPRPPLYFGGSSDAGIDVAVDTVDKYLTWGEPPAQVAEKIARVREVANARGRKLSFGIRLHVIVRETNEEAWSAANELIKHVSDDTIARAQRNFARMDSVGQQRMAQLHGGKRDKLEISPNLWAGVGLVRGGAGTALVGDAQTVAARIKEYQDIGIDTFIMSGYPHLEEAYRFAELVFPLLSLDHGSNVTRLHHNSGPFGETVGNDYRPSRLASQS
What is the function of this protein?
Catalyzes the desulfonation of aliphatic sulfonates.
What are the official names of this protein?
Alkanesulfonate monooxygenase, FMNH2-dependent aliphatic sulfonate monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the SsuD family.
Protein: TCOF_HUMAN
Sequence: MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV
What is the function of this protein?
Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification (PubMed:12777385, PubMed:26399832).  Required for neural crest specification: following monoubiquitination by the BCR(KBTBD8) complex, associates with NOLC1 and acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification (PubMed:26399832).
What are the official names of this protein?
Treacle protein, Treacher Collins syndrome protein.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: NU5M_ALBCA
Sequence: MLLGVLCAIMGVIYMVLNMQNSSYLLMFNLFSTQSVNFNLALICDKVSTSFLVVVLLISSCVFLFANEYMSEDHYNIRFGWILISFVASMGILILSGSIFTLLLGWDGLGLTSFALIAYYDNYNASSSAFLTLMTNRLGDVLIIATFSVILVTGLTVHFPPYTLVWLSSILFTIASFTKSAQYPFSAWLPAAMAAPTPVSALVHSSTLVTAGIYLMIRCFMVDGAPAEMYSLMGLVGSITCLLGGSVALFEYDLKKVIALSTLSQLGVMMYSLSLNLPYLALLHLYGHAMFKAMLFLGAGLILMMSYGTQDLRLLGSLLYSSPIVISLLNISMLCLMGFPFVSSFYSKHLILEKMLDMNCNFFTSMMFMLGTLLTGMYSIRLMKFLCWGNNNNKPSYCNMSWQSKMSMFPLAALAVLSGQLMSYLDSSYMTFSWSTNQYNLILWGVLFLSIFFGIVMKFGNFYPTLMSSMMFLGPTSYNLLHYTKSLLIYMKRIDLSISEPNWVMSNLMYSSSWRVMSLFNWLTNYMLVTWFLLVWLMIMSILMW
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HSSR_STAA1
Sequence: MVQCLVVDDDPRILNYIASHLQTEHIDAYTQPSGEAALKLLEKQRVDIAVVDIMMDGMDGFQLCNTLKNDYDIPVIMLTARDALSDKERAFISGTDDYVTKPFEVKELIFRIRAVLRRYNINSNSEMTIGNLTLNQSYLELQVSNKTMTLPNKEFQLLFMLAARPKQIFTREQIIEKIWGYDYEGDERTVDVHIKRLRQRLKKLNATLTIETVRGQGYKVENHV
What is the function of this protein?
Member of the two-component regulatory system HssS/HssR involved in intracellular heme homeostasis and tempering of staphylococcal virulence.  Phosphorylated HssR binds to a direct repeat sequence within hrtAB promoter and activates the expression of hrtAB, an efflux pump, in response to extracellular heme, hemin, hemoglobin or blood (By similarity).
What are the official names of this protein?
Heme response regulator HssR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFBV_ECO8A
Sequence: MSTPDNRSVNFFSLFRRGQHYSKTWPLEKRLAPVFVENRVIKMTRYAIRFMPPIAVFTLCWQIALGGQLGPAVATALFALSLPMQGLWWLGKRSVTPLPPAILNWFYEVRGKLQESGQVLAPVEGKPDYQALADTLKRAFKQLDKTFLDDL
What are the official names of this protein?
UPF0208 membrane protein YfbV.
What is the protein family that this protein belongs to?
Belongs to the UPF0208 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SC61A_DISMA
Sequence: MGIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMIITIGQAIVYVMTGMYGDPSEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRGTEFEGAIIALFHLLATRTDKVRALREAFYRQNLPNILNLIATVFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLGTWSDATSGGPARAYPVAGLCYYLSPPESFGSVLDDPVHAAIYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEMGSMGALLF
What is the function of this protein?
Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER).  Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides.  May cooperate with auxiliary protein SEC62, SEC63 and HSPA5/BiP to enable post-translational transport of small presecretory proteins.  The SEC61 channel is also involved in ER membrane insertion of transmembrane proteins: it mediates membrane insertion of the first few transmembrane segments of proteins, while insertion of subsequent transmembrane regions of multi-pass membrane proteins is mediated by the multi-pass translocon (MPT) complex.
What are the official names of this protein?
Protein transport protein Sec61 subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localizes exclusively in granular structures in the endoplasmic reticulum (ER).
Protein: RS7_NEIMA
Sequence: MPRRREVPKRDVLPDPKFGSVELTKFMNVLMIDGKKSVAERIVYGALEQIEKKTGKVAIEVFNEAIANAKPIVEVKSRRVGGANYQVPVEVRPSRRLALAMRWVRDAARKRGEKSMDLRLAGELIDASEGRGGALKKREEVHRMAEANKAFSHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: NRDR_HAEDU
Sequence: MRCPFCTAEETKVIDSRLAADGYQIRRRRECIGCKERFTTFESAELALPYIIKNNGNREPFDLNKLEVSLNRALEKRPVHADDVDNVISKIIFQLKALGEREVPSKSVGHLAMDGLKQLDKVAYIRFASVYLSFDDIEEFTKEIEKLRE
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: O27A_CONPE
Sequence: MEKLTILLLVAAVLMSTQAQNQEQRQQAKINFLSKRKPSAERWRRDCTSWFGRCTVNSECCSNSCDQTYCELYAFPSFGA
What is the function of this protein?
Gamma-conotoxins may act on voltage-gated non-specific cation pacemaker channels (HCN).  Triggers depolarization and firing of action potential bursts in the caudodorsal neurons of lymnaea.  This effect is due to activation or enhancement of a slow inward cation current that may underlie endogenous bursting activity of these neurons.
What are the official names of this protein?
Gamma-conotoxin PnVIIA, PnMEKL-011.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O2 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YBEY_CORDI
Sequence: MSIEVVNESGFDGVNEEALIDVATFVLGEMDVHPDAEATISVVDVATMSDLHVRWMDLEGPTDVMSFPMDELTPGMGRPDAQPFGPAMLGDIILCPEFAAKQAAKAGHDMGHELALLTTHGCLHLLGYDHIEPEDEQEMFALQNELLQDWYTYCARRGVEFQPKPSNAGAFPSAADRAELDKLVPGGGIPAIGEPQ
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_XANAC
Sequence: MPNRPNVRGVYLITPDEPNTQRLLLRTAPLLGSITWLQYRNKQADAALRLRQAGALREACAAHGVPLIINDDAQLAAQVGAQGVHLGEDDGDVAAARALLGEQAIIGVSCYDDIERGRAAAASGASYVAFGAFFPTTTKQTTRRATPALLQQAAELDVPRVAIGGIAPAQVPALVTAGADLIAVVSGVYAAPDPVAAVQGYRAGFAAQRGKL
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: NDUB2_PANTR
Sequence: MSDLTRLASFARVGGRLFRSGRARTAGDGGVRHAGGGVHIEPRYRQFPQLTRSQVFQSEFFSGLMWFWILWRFWHDSEEVLGHFPYPDPSQWTDEELGIPPDDED
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial, Complex I-AGGG, CI-AGGG, NADH-ubiquinone oxidoreductase AGGG subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB2 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: BIOF_BACCQ
Sequence: MNQTWRTHLQSKLQQLHEREQYRNLHVTEQAEETWLIRDEKRMLNLASNNYLGLAGDERLKEAAIACTRKYGTGATASRLVVGNYSLYEEVERSICDWKGTEKALVVNSGYTANIGVISSLVSRHDIVFSDKLNHASIVDGIILSGAEHKRYGHNDLDHLEKLLKTASPEKRKLIVTDTVFSMDGDTAYLRELVELKEKYGAILIVDEAHASGIYGIGGAGLSHIEDLAQKIDIHMGTFSKALGCYGAYLTGDAIYIEYLHNMMRSFIFTTALPPGTLGAVQKAIEIVQEDHKRRENLIANGEYFRSKLRDAGFNIGNSSTHIVPIVVGSNENALRFSKRLQEAGIAAIAIRPPTVPINSSRIRFAVTSQHTIADLKWAIDRIIHIAKEEELFV
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
Putative 8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: SCD2_SCHPO
Sequence: MLKIKRTWKTHSRILDKDPFSIEPPRKVIRALYDYTARKATEVSFAKGDFFHVIGRENDKAWYEVCNPAAGTRGFVPVSHFEEIGKTVKSERDSDGSGQISFTDLTTNSSTTRSSISELHSGSQPLFGIVQFDFAAERPDELEAKAGEAIIIIARSNHEWLVAKPIGRLGGPGLIPLSFIQLRDLKTGAVIKDVSEAVLRISCIPRVEDWKRAAADYKKSSIPLGKFSDGETQTMPSLSPSTENLQINNDVTYQAATDNSSTFPGSVANELTPLQTLESRTASIASKNKKDMSSEPTVVAAMVENYMIRDDQYWYLVRAVMSDGKHRNLCRYYEDFFNFQTKFLELFPNEAGRGDERRVIPYMPGPVDDVNELISSQRAMDLDVYLKEMCRLPARLLENELVKLFFLPLDGDVESPHPTSTMPEALPREPLSFSLPEKAPEKATNISIPESAPTTAGSTCKVKVRLGDETFALRVPSDISFEDFCERLTNKLGECEHLSYRDTNANKVLPLNNVDDLRKACSQESGVLLFAERRRF
What is the function of this protein?
Required for mating and morphogenesis.  Interacts directly with scd1 and with cdc42.  May bridge and facilitate scd1 and cdc42 interactions.
What are the official names of this protein?
Protein scd2/ral3.
Protein: RRF2M_DANRE
Sequence: MLLSLTFPVLRGCTGHLVNRSLQAPRWRVTWKRSYSLLQDEVKSLRTVVNPDISKIRNIGIMAHIDAGKTTTTERMLYYSGYTRALGDVDDGDTVTDYMAQERERGITIQSAAVTFDWKDYRINLIDTPGHVDFTLEVERALRVLDGAVAVFDASAGVEAQTMTVWRQAEKHQIPCVCFLNKMDKPAASLRYSLDSIKAKLKANPVLLQIPIGSGKSFTGLVDLITRQKMMWQGNALTNDGRSFEINSLQPSDDPNVLLAVSEARAALIEQVADLDDDFAELLLGEYGENFDAVPAVKLQEAVRRVTLARKGVPVLCGSSLKNKGVQPLLDAITAYLPAPNERNHDLVRWYKNDLCALAFKVVHDKQRGPLVFVRIYSGSMKAQSSVHNINRNETEKMSRLLLPFADQQIEIPSLSAGNIALTVGLKQTVTGDTIVSSKASAAAAIRRAQAEAESRSNSHSAALAGVEVPEPVFFCSIEPPTMAKQADLEHALNCLQREDPSLKVRIDPDSGQTVLCGMGELHIEIIHDRIKREYKIETHLGPLQVAYRETILQSATAKDLLDRILGEKRHVVSVELTVHPLKENSSASCDITFEEDVKAMLPADVREAVENGVQSAYLQGPVLGFPVQGVQTVIQNVRLESGTSAAMVSACVSRCMLKALKQAGGQVLEPVMALEVTVGEEHLSSVLADLSQRRGTICDIQSRQDNKILLADVPLAEMMGYSTVLRTLTSGNATFSLELSSYEPMNSQDQNILLNKMAGLT
What is the function of this protein?
Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.  Acts in collaboration with mrrf.  GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit.  Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
What are the official names of this protein?
Ribosome-releasing factor 2, mitochondrial, RRF2mt, Elongation factor G 2, mitochondrial, EF-G2mt, mEF-G 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: OTCC_OENOE
Sequence: MEQKLGNLVKKNVVNSVFQGRSLLAEKDFTPMELEYLIDFALHLKALKKLGISHRYLEGKNIALLFEKTSTRTRSAFTTASIDLGAHPEFLGSNDIQLGKKESVEDTARVLGSMFDGIEFRGFKQSVVDDLARYSGVPVWNGLTDEWHPTQMLADFMTIKENFGHIKNINLSYMGDGRNNTANSLLITGSMLGANIRIVSPKELQPSEKTTELAKKFAEKSGSRFLITDNIDEGVSKTNVLYTDVWVSMGESDWEDRVKLLKPYQVNMETIRKTSTPDDQLIFMHCLPAFHDINTDYGHEIFEKYGIKEMEVTDEVFRSIYARQFEEAENRMHSIKAIMAATLGNLFIPHV
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, catabolic, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_ONYPE
Sequence: MFAIIKTGGKQFRVFEGQEIYVEKLNVEPETTYQFQEVLAVGGSNPVLGTPFVKDAKVTAQVIKHDRAKKIIVFKYKKRKKYRCKQGHRQSYTKLLITKITV
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: COHA1_CANLF
Sequence: MDVTKKNKRDGSEVTERIITETVSTRLTSLPPKGGTSNGYAKTGSLSGGSRLEKHSLTHGSSGYINSSGSTRGNASTSSYRRAHSPASTLPNSPGSTFERKIHITRHGTYEGSSSGNSSPEYPRKEFASSSTRGRSQTRESEIRVRLQSASPSTRWTELDDVKRLLKGSRSASVSPTRNSSNTLPIPKKGTVETKMVTASSQSVSGTYDATILDANLPSHMWSSTLPAGSSMGTYHNNVTTQSSSLLNTNAYSAGSVFGVPNNMTSGSSTLHPGVSTCSSVFGMQNNLAPSSSTLSHSTATASTAYGMKKNLPQSPAVVSTGVSTSAACTTNVQNEDLLHKDCKFLILEKDNTPAKKEMELLIMTKDSGKVFTASPASIAATSFSDDTLKKEKQAAYTADTCLVSDANGDVKTVSTKGKAASAEMHNYNHRGGGSGGGGGGGGGGGGGPWGAAPAWCPCGSCCSWWKWLLGLLLTWLLLLGLLFGLIALAEEVRALKARVAELEQSRSNVLLFKEEMQRANKDWLQGEAPSVEAGGKLGLDGHQQEELWLFVRNRLMAEQENGNLRGSPGPKGDMGSQGPKGDRGLPGTPGIPGVLGHPGPQGPKGQKGSVGEPGMEGPMGQRGREGPMGPRGEPGPPGFGEKGDRGAAGEPGVQGPPGVPGSVGPKGSGGSPGPRGPPGPMGPQGLRGEVGLPGIKGDKGPLGSPGPKGDQGEKGPRGLTGEPGLRGLPGAVGEPGAKGAVGPAGPDGHQGPRGEQGLTGMPGTRGPPGPSGDPGKPGFTGPQGPQGLPGTPGRPGAKGEPGAPGRIMTSEGSSTITVPGPPGPPGAMGPPGPPGAPGPRGERGLAGESFMGSSSSISELLSTRSFKEPMQTCHRASFLEARVAKTTPALSGRHCVLDTCRKGVDLRGPPGPPGPPGPPDLPFRVRQDPEAPQVKAELPGKRYESIGTQSLGLALGKSLPATSPQHRVLETYFSGPPGPPGPPGPKGDQGSSSLGLNLQGPPGPRGPKGDKGGSSSSTMFMPGPPGPPGPPGPPGSISSSGREIQQYISEYLQSDSIRSYLSGVQGPPGPPGPPGPVTTIAGETFDYSELASRVSSYLQTSGYSIGSSVSISTEDIVAALQREYLRRAGGWEPWGLGLPLPELLRASEEALVLVPSGQGRPGCGRAVAREPCGLGGPTPALPVLAGDDVRQYLRQYVIGDWSLQSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLQGSEYRGIIGPPGPPGPPGIPGNAWSSISVEDLSSYLHTAGVSSIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLVSMDGSYSRDSRSSSHSASVSRGSSYSSSMGIGGASGGSLGEAGAFGLDMGLGRGYGGAAEGGMYGGEGGPLGAGFAGGLDYNELAVRVSESLQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTEDLMDFFRSKSTSVIVFLTPCCPVRGALQDHQVGLGHPALEGTREKKETKVTKSMRGGEREASPSSHELPLEEQPLASVLAMAYGVHVKISPKGGSWRLTSY
What is the function of this protein?
The 120 kDa linear IgA disease antigen homolog is an anchoring filament component involved in dermal-epidermal cohesion.
What are the official names of this protein?
Collagen alpha-1(XVII) chain, 180 kDa bullous pemphigoid antigen 2, Bullous pemphigoid antigen 2.
What are the subcellular locations of this protein?
Cell junction, hemidesmosome. Membrane; Single- pass type II membrane protein. Note=Localized along the plasma membrane of the hemidesmosome. SUBCELLULAR LOCATION: [120 kDa linear IgA disease antigen homolog]: Secreted, extracellular space, extracellular matrix, basement membrane.
Protein: LEUD_BUCPS
Sequence: MTLLNQYTGIVIPINISNIDTDVIIPKQFLKKINKKGFGKYLFYNWRFNDNEGKNINKNFILNDLRYKKSSILLTRDNFGCGSSREHAVWALMDYGFKVIIASSFGDIFYNNCLNNHLIPIILSENKINTLFDITSNYIDVSFTIDLKNNTILAKNYAYYFKIDALHKFCIMHQLDQIDLTMKNEKKITKYEKKIFDFFIKK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: NUOB_EDWI9
Sequence: MDYTLTRIDPDGDNDRYPLQKQEVVSDPLEQHVHRSVYMGKLDHALHDMVNWGRKNSLWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADFMVVAGTCFTKMAPVIQRLYEQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFIPVDVYIPGCPPRPEAYMQALMLLQESIGQERRPLSWVVGDQGVYRANMQSERERKRAERIAVTNLRTPDEI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: QCR7_FASHE
Sequence: MATLRASVERVASAYRMRLKQMTDLQQKVKAFQFSNSYYNQLGLLYHDVIPHSPLIAEAVRRLPREETEARDFRIARAFQLSASKTVLPKEQWTAIEDDIPYLDPYIEVAKKEWKEKAEWDHFVNPETYP
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
What are the official names of this protein?
Cytochrome b-c1 complex subunit 7, Complex III subunit 7, Complex III subunit VII, Ubiquinol-cytochrome c reductase complex 14 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the UQCRB/QCR7 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: ISPE_STAEQ
Sequence: MIYETAPAKINFTLDTLFKRDDGYHEIEMVMTTVDLNDRLSFEKRTDNKIVVDIEHNYVPNDNKNLAYKAADLMFERFNINEGVTISIDKDIPVSAGLAGGSADAAATMRGLNRLFGLGQSLDALAALGIQIGTDIPFCIYNQTAVCTGRGEQVTFLKRPPSAWVVLAKPNIGISSPDVFKALDLTEEHIVHNEKCKQALENNDYHLLCNSLSNRLEPVSMAMHPDIKKIKDNMLQCGADGALMSGSGPTVYGLAQKERQAKNIYNAVNGCCNEVYLVRLLG
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: HISM_ECO57
Sequence: MIEILHEYWKPLLWTDGYRFTGVAITLWLLILSVVIGGVLALFLAIGRVSSNKYIQFPIWLFTYIFRGTPLYVQLLVFYSGMYTLEIVKGTEFLNAFFRSGLNCTVLALTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGFSTFKMYRCIILPSALRIALPAYSNEVILMLHSTALAFTATVPDLLKIARDINAATYQPFTAFGIAAVLYLIISYVLISLFRRAEKRWLQHVKPSSTH
What is the function of this protein?
Part of the histidine permease ABC transporter.  Also part of a lysine/arginine/ornithine transporter.  Probably responsible for the translocation of the substrate across the membrane.  Required to relay the ATPase-inducing signal from the solute-binding protein to HisP (By similarity).
What are the official names of this protein?
Histidine transport system permease protein HisM.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.