PharMolix/UniProtQA huggingface dataset:
Protein: Y398_GLAP5
Sequence: MENSKKQSFQDMLDYVHLYRLKNKLLRETADNDRKIRDNQKRILLLDNLNQYITDNMSIQDIRVIIGNMRDDYENRVDDYAIRNAELSKERREIRRKMAEHSSKK
What are the official names of this protein?
UPF0265 protein HAPS_0398.
What is the protein family that this protein belongs to?
Belongs to the UPF0265 family.
Protein: APOA1_MUSPA
Sequence: MKAVVLAVALVFLTGSQAWHVWQQDEPQSRWDKVKDFATVYVDAVKDSGRDYVSQFESSSLGKQLNLNLLENWDTLGTTVGQLQERLGPLTRDFWDNLEKETDWLRQEMNKDLEEVKQNVQPYLDEFQKKWNEDVELYRQRVAPLGAELHESARQKLQELQGKLSPVAEEFRDRMRTHVDALRTQLAPHSDKLRESLAQRLAELKSNPTLNEYHTRAKTHLNTFGEKARPALEDLRHTLIPILDTLKTKVKSVIDKARETLTAQ
What is the function of this protein?
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT).  As part of the SPAP complex, activates spermatozoa motility.
What are the official names of this protein?
Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.
Protein: ZBT21_HUMAN
Sequence: MEGLLHYINPAHAISLLSALNEERLKGQLCDVLLIVGDQKFRAHKNVLAASSEYFQSLFTNKENESQTVFQLDFCEPDAFDNVLNYIYSSSLFVEKSSLAAVQELGYSLGISFLTNIVSKTPQAPFPTCPNRKKVFVEDDENSSQKRSVIVCQSRNEAQGKTVSQNQPDVSHTSRPSPSIAVKANTNKPHVPKPIEPLHNLSLTEKSWPKDSSVVYAKSLEHSGSLDDPNRISLVKRNAVLPSKPLQDREAMDDKPGVSGQLPKGKALELALKRPRPPVLSVCSSSETPYLLKETNKGNGQGEDRNLLYYSKLGLVIPSSGSGSGNQSIDRSGPLVKSLLRRSLSMDSQVPVYSPSIDLKSSQGSSSVSSDAPGNVLCALSQKSSLKDCSEKTALDDRPQVLQPHRLRSFSASQSTDREGASPVTEVRIKTEPSSPLSDPSDIIRVTVGDAATTAAASSSSVTRDLSLKTEDDQKDMSRLPAKRRFQADRRLPFKKLKVNEHGSPVSEDNFEEGSSPTLLDADFPDSDLNKDEFGELEGTRPNKKFKCKHCLKIFRSTAGLHRHVNMYHNPEKPYACDICHKRFHTNFKVWTHCQTQHGIVKNPSPASSSHAVLDEKFQRKLIDIVREREIKKALIIKLRRGKPGFQGQSSSQAQQVIKRNLRSRAKGAYICTYCGKAYRFLSQFKQHIKMHPGEKPLGVNKVAKPKEHAPLASPVENKEVYQCRLCNAKLSSLLEQGSHERLCRNAAVCPYCSLRFFSPELKQEHESKCEYKKLTCLECMRTFKSSFSIWRHQVEVHNQNNMAPTENFSLPVLDHNGDVTGSSRPQSQPEPNKVNHIVTTKDDNVFSDSSEQVNFDSEDSSCLPEDLSLSKQLKIQVKEEPVEEAEEEAPEASTAPKEAGPSKEASLWPCEKCGKMFTVHKQLERHQELLCSVKPFICHVCNKAFRTNFRLWSHFQSHMSQASEESAHKESEVCPVPTNSPSPPPLPPPPPLPKIQPLEPDSPTGLSENPTPATEKLFVPQESDTLFYHAPPLSAITFKRQFMCKLCHRTFKTAFSLWSHEQTHN
What is the function of this protein?
Acts as a transcription repressor.
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 21, Zinc finger protein 295.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes with ZBTB14 in nucleus in HEK293 cells.
Protein: CETP_CRIGR
Sequence: MLAVTLLSLALLGSTCACSTSTSYEAGIVCRITKAALLVLNQETAKVIQTAFQRASYPDIKGERSMMLLGRVTYGLHNIQISHLSIASSQVELVEAKSVDVSIQNASVIFKGTLNYGYKGAWGLNIEQSVDFEIESAIDLQINTKLTCDSGHVRTDAPDCSISFHKLLLHLQGEREPGWTKQLFTNIISFTLKMVLKGQVCKEINVISNIMADFVQTRAANIISDRDIEVDISLTRSPIITATYLESHHKGHFIYKNISEVLPLPAFSPTLLGDTRMLYFWFSEQVLDSLAKAAFQDGRLQLNLAETELKVVLETWHFNPNQEIIPEVITGFPSPGQVTVHCPRRPTISCQNKGVVVSSPVVMEFLFPHKDGQDSVTHTFEEDIVATIQASYSKKKLFLSLVDFQIKPKTTSNMAESSESIQNFLQLMITTVGIPEIMSRLEVALTTLMNSKGLDLFDIINPEIITRDGFLLLQMDFGFPEHLLVDFLQSLN
What is the function of this protein?
Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles.  Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL (PubMed:24293641).  Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (By similarity).
What are the official names of this protein?
Cholesteryl ester transfer protein, Lipid transfer protein I.
What is the protein family that this protein belongs to?
Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
Protein: KTHY_PROM2
Sequence: MKGKFIVIEGIDGCGKTTQIDELSKWLPSSGLIKKGSKLITTREPGGSHLGKRLRGLILDNNQNNKPSPLAELLLYSADRAEHVYKIISPALNNNDWVISDRFSDSTLAYQGYGRNINLEIIKNIESIVCQGESPDLTFFLEISPEESIFRRKNQIPDRIESEGIEFLEKVNKGFKIIAKEKNWTVISASQNIKTISNQIKETVLNNFSKNT
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: CMR1_PICGU
Sequence: MTLSDFEKQRQENIQRNKELLRQLELDSLNDSISREVPKPKPKAKRRKTENARVKTEPIMPSRRSRRLAGSTMEDSEEDKQMREEMEKAEERKRELEKLKSTRLFGDFKLIDLVVNKQGEFKNQDKILKAKEKDNEIKKEEKEEIKKEEDSTDSIDLSRDNEVLQKLQQLGDRFSAGDFYEMIKDTKSKYDDTVLQEKREEFDRVKLYERFDPLDIKITQQRITSIAFHPAKDDRVVVAGDTTGYVGIWAVDAKGDDETSPHITILKPHGKAVARILTPEQQPSSILTCSYDGSVRRLDLKRLESTEVAYLQDPYESSDYPLGVSDINVADNNLLYMTTLSGNFYRYDMRSPFKQGELLRLHDKKIGSFSINPNAFHQIATASLDRTMKLWDLRNISQKNSYWSEFDDKSPHLYCTYHSRLSVSCVDWNHDNHLVCNGYDDTVNVFDLSGSDKLPLVTEWSKDYETEKKKRTTIEDGVPEKLEALTRIKHNCQTGRWVSILKSKWQLHPADGLQKFVIANMNRAFDIYDQKGRILCHLTDPDRMTAVPAVSMLHPTENWCVGGSASGKVYLFE
What is the function of this protein?
DNA-binding protein that binds to both single- and double-stranded DNA.  Binds preferentially to UV-damaged DNA.  May be involved in DNA-metabolic processes.
What are the official names of this protein?
DNA damage-binding protein CMR1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DDB2/WDR76 family.
Protein: AQP4_DIPME
Sequence: MSDRPAARPWGKCGSLCRREEIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWGGKENPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPPSVVGGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGGLYEYVFCPDVELKRRFKEAFSKAAQQTKGSYMEVEDNRSQVETEDLILKPGLVHVIDIDRGDEKKGKDPSGEIAQTQH
What is the function of this protein?
Forms a water-specific channel.  Plays an important role in brain water homeostasis and in glymphatic solute transport.  Required for a normal rate of water exchange across the blood brain interface.  Required for normal levels of cerebrospinal fluid influx into the brain cortex and parenchyma along paravascular spaces that surround penetrating arteries, and for normal drainage of interstitial fluid along paravenous drainage pathways.  Thereby, it is required for normal clearance of solutes from the brain interstitial fluid, including soluble beta-amyloid peptides derived from APP.  Plays a redundant role in urinary water homeostasis and urinary concentrating ability.
What are the official names of this protein?
Aquaporin-4, AQP-4.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Endosome membrane. Cell membrane, sarcolemma; Multi-pass membrane protein. Cell projection. Note=Activation of the vasopressin receptor AVPR1A triggers AQP4 phosphorylation at Ser-180 and promotes its internalization from the cell membrane (By similarity). Detected on brain astrocyte processes and astrocyte endfeet close to capillaries (By similarity).
Protein: GSA2_STAA9
Sequence: MNFSESERLQQLSNEYILGGVNSPSRSYKAVGGGAPVVMKEGHGAYLYDVDGNKFIDYLQAYGPIIAGHAHPHITKAIQEQAAKGVLFGTPTELEIEFSKKLRDAIPSLEKIRFVNSGTEAVMTTIRVARAYTKRNKIIKFAGSYHGHSDLVLVAAGSGPSQLGSPDSAGVPESVAREVITVPFNDINAYKEAIEFWGDEIAAVLVEPIVGNFGMVMPQPGFLEEVNEISHNNGTLVIYDEVITAFRFHYGAAQDLLGVIPDLTAFGKIVGGGLPIGGYGGRQDIMEQVAPLGPAYQAGTMAGNPLSMKAGIALLEVLEQDGVYEKLDSLGQQLEEGLLKLIEKHNITATINRIYGSLTLYFTDEKVTHYDQVEHSDGEAFGKFFKLMLNQGINLAPSKFEAWFLTTEHTEEDIQQTLKAADYAFSQMK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 2, GSA 2, Glutamate-1-semialdehyde aminotransferase 2, GSA-AT 2.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROL_ECOSE
Sequence: MTQPLFLIGPRGCGKTTVGMALADSLNRRFVDTDQWLQSQLNMTVAEIVEREEWAGFRARETAALEAVTAPSTVIATGGGIILTEFNRHFMQNNGIVVYLCAPVSVLVNRLQAAPEEDLRPTLTGKPLSEEVQEVLEERDALYREVAHIIIDATNEPSQVISEIRSALAQTINC
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase 2, SK 2.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family. AroL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_ARTS2
Sequence: MSLTIPSPASGTSTSATTDTAPAAAPQRTYQVRTFGCQMNVHDSERMAGMLEDAGYVPASGENADVVVFNTCAVRENADNKLYGNLGMLAPVKAANPGMQIAVGGCLAQKDRETILKKAPWVDAVFGTHNVGALPALLDRARHNNEAQLEILESLDVFPSTLPTKRDSVYSGWVSISVGCNNTCTFCIVPALRGKEKDRRPGDILAEIQALVDDGAIEVTLLGQNVNSYGVEFGDRQAFSKLLRACGEIQGLERVRFTSPHPAAFTDDVIDAMAETPNVMPQLHMPLQSGSDKVLKDMKRSYRSTKFLGILDKVRERIPHAAISTDIIVGFPGETEEDFQATLDVVEKSRFATAFTFQYSKRPGTPAADLPDQLPKAVVQERFERLTALQDRIAAEENARQLGRRVEVMVTAQSGRKSEETHRLSGRSQDQRLVHFSVPEGAEKPRPGDLVTVTITEAAAFHLVADPASAADYSLRRSRAGDAWDRSQADSCGAPVAGGGAGSNGGKGGVSLGMPALPVRRS
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ETS6_DROME
Sequence: MAILQNSRQSHKQLPIISQTIRSAWCQQRPINAMHQDVRQKSIGSGNETKLEAKETEVPTNRRRRRRRCSSSSTSDSSASSYSSTDSDSGSSTSSSSIRSQLPALNLPVPLPLATPTPPAVSSPHQAPSPRRNSSDSNRSVSPVEVPVDPHAWTPEDIASWVRWATRKFKLDPEPDIDRFPKDAQELCDLSRADFWVCAGSRRGGMLLAQHFAISLYHATGRETSPMLNDDEPNPYQLLNAASHRLVAQGSGGQIQLWQFLLELLADSSNANAISWEGQSGEFRLIDPDEVARRWGERKAKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGLMAACQAQAQGGDPASSMLGSYNHHAGGAMQLGRHPPPLHHHPQHSHPHHQLGQPHFLHPHHSSPASNSSSLGFPSSSTASSQASPGQAPASSSASTSNFTAPFQGGTAGVDPARTSTSSAGNYDQGPVTPTTNAFN
What are the official names of this protein?
DNA-binding protein D-ETS-6.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NU1M_VARBA
Sequence: MSPSLVTLNSLMYIIPILIAVAFLTLTERKILGYMQHRKGPNITGPHGLLQPIADGLKLFIKEPVRPLNASPTLLILSPLLAITAAMLIWAPIPMPYSLANLNLGLLSILAISGMAVNSILWAGWASNSKYALIGSLRAVAQTISYEVTLGIILLSTLVLTGGFTIQLLTITQKYTWLLTTSWPLTMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAGGPFALFFLAEYANIITMNLLTCILFINPGPSQYPELFLANLIAKTTILCLSFLWIRASYPRFRYDQLMHLLWKQFLPMTMALCLLHASLSISISGLPPHP
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y3660_MYCTU
Sequence: MLTDPGLRDELDRVAAAVGVRVVHLGGRHPVSRKTWSAAAAVVLDHAAADRCGRLALPRRTHVSVLTGTEAATATWAAAITVGAQHVLRMPEQEGELVRELAEAAESARDDGICGAVVAVIGGRGGAGASLFAVALAQAAADALLVDLDPWAGGIDLLVGGETAPGLRWPDLALQGGRLNWSAVRAALPRPRGISVLSGTRRGYELDAGPVDAVIDAGRRGGVTVVCDLPRRLTDATQAALDAADLVVLVSPCDVRACAAAATMAPVLTAINPNLGLVVRGPSPGGLRAAEVADVAGVPLLASMRAQPRLAEQLEHGGLRLRRRSVLASAARRVLGVLPRAGSGRHGRAA
What is the function of this protein?
May play a role in septum formation.
What are the official names of this protein?
Uncharacterized protein Rv3660c.
Protein: ANEC_ASPA1
Sequence: MTPDLVARFWLVELHVRLPAWLRGITSASASVAVKRPGSSKKPLEPAPQPAPYKPTHYRHIIYAYDVMEEKCEIPVLEHDPFDFLDPQKTLVPPENTILIDPVAVGLPWFSTMKGTPQCIHWREAEAAGLELIEQVMAARGAGAVIPEKLKTSDQRRKMMELVETAVTICIYLYAVSDAARIRVLTKSIVFLFLHDDVMESKANAEGNSILEGWDTDTFKANELEGESRNDIFLDFCREAIALDPVLGLELMQDTVRWARYSRVNSTKADKTHATWQDFRDFRELDIAYDFMITAVRFGAAILYDPAERPVFEWIEKLYIRHCLYINDLYSYEKEFREHQQEGAPLHNSVHMIEQVLSVPPGSAKAILRSVLWDCERQVREEYVRLMQLPELTHTQKVYLQRLIESFAGNYMYSMSTYRYARLSGKLIGPPPEDCLLKNYVQ
What is the function of this protein?
Terpene cyclase; part of the gene cluster that mediates the biosynthesis of aculenes, a unique type of norsesquiterpenes that contain a nordaucane skeleton linked to an L-proline moiety and are of mixed biosynthetic origin (PubMed:31618514).  The pathway begins with the synthesis of dauca-4,7-diene by the terpene cyclase aneC using farnesyl pyrophosphate (FPP) as substrate (PubMed:31618514).  The cytochrome P450 monooxygenase aneF then performs the initial oxidation at C-12 of dauca-4,7-diene to yield asperaculane D (PubMed:31618514).  Asperaculane D is substrate of the cytochrome P450 monooxygenase aneD for C-10 hydroxylation to yield asperaculane E (PubMed:31618514).  The cytochrome P450 monooxygenase aneG then converts asperaculane E into aculene D via C-2 oxidation (PubMed:31618514).  The monomodular nonribosomal peptide synthtase aneB adenylates L-proline and the thiohydrolase aneE transfers this activated L-proline derivative to aculenes D and C to produce respectively aculenes B and A (PubMed:31618514).  The dioxygenase aneA converts aculene D into aculene C, and aculene B into aculene A by introducing the 5,6-alkene moiety (PubMed:31618514).  Asperculanes A, B, C and F, as well as 14-prolyl asperculane C, might be shunt products of the pathway (PubMed:31618514).
What are the official names of this protein?
Terpene cyclase aneC, Aculenes biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: YO10_ADEG1
Sequence: MIDKRNKKAVTHISTCLCHSSIPIYGDSPFLNTHRAAMDPRPLVLLLLLASHISTFRQMYFEGETIHFPMGIYGNETTLYMNDIILEGTRANTTTRTISLTTTKKNAGTNLYTVISETGHNATYLITVQPLGQSIHHAYTWAGNTFTLQGQVFEHGNYTRWVRLENAEPKLIISWALSNRTINKGPAYTANMDFDPGNNTLTLHPVLITDAGIFQCVIDQQTNLTLTINFTVSENPPIVAHLDIHKTISRTIAICSCLLIAVIAVLCCLRQLNVNGRGNSEMI
What are the official names of this protein?
Putative Ig-like domain-containing protein ORF10.
Protein: EFG_CLOB8
Sequence: MARKYPLDKFRNFGIMAHIDAGKTTTTERILFYTGVSHKIGEVHDGEATMDWMVQEQERGITITSAATSCFWKEHELNIIDTPGHVDFTVEVERSLRVLDGAVTVLDAKSGVEPQTETVWRQADKYGVPRMIYVNKMDATGADFFRCIQTVKDRLKANAVPIQIPVGSEQGFKGMVDLIKNVAFIFYDDLGKDMREEAIPAEYADQAEEYRAAMIEAIAETDEELMEKYLEGEELTIEELKAALRKATIANEIYPCICGSSYKNKGVQEMIDGVVDYLPSPLDVPAIKGTTLDGEEDHRNSSDSEPLSALAFKIATDPFVGKLAFTRIYSGVMQSGSYVLNSTKGKKERIGRLVKMHSNSRSEVESLEAGEIGAVIGLKNTTTGDTLCAENSPIILEAMEFPEPVIRVAIEPKTKDAQEKMGMALAKLAEEDPTFKTWTDTETGQTIIAGMGELHLEIIVDRLQREFKVECNVGAPQVAYKETIRSAVKAEAKYAKQSGGKGQYGHAVIEMEPTEGEYVFENAVVGGAIPKEYIPAIDAGIQEASKNGIIAGYNVINFKVKLVHGSYHEVDSSEMAFKIAGSMAFKNAMSKASPVLLEPMMKVEVTVPEEYMGDVIGDINSRRGIMEGMEALNGAQVIRAFVPLSEMFGYATTLRSRTQGRGVYSMVFDHYDEVPKNIQEQIAGSRAK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_BURL3
Sequence: MPHSSSGAPLDPVAFIHSQIRTVPDWPQPGVMFRDITTLLQSPKALRILVDLFVERYVDAKLDYVAGLDARGFIIAPIVAYELSVGFVPIRKVGKLPYKTRSESYDLEYGSATVEIHEDACRPGDRVIIMDDLIATGGTMMAGRNLLQRLGAEVVEGAAIIDLPDLGGSALLRNAGLPVYTVTEFAGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBC35_ARATH
Sequence: MANSNLPRRIIKETQRLLSEPAPGISASPSEDNMRYFNVMILGPTQSPYEGGVFKLELFLPEEYPMAAPKVRFLTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLSENIAKHWKSNEAEAVDTAKEWTRLYASGA
What is the function of this protein?
Catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'.  This type of poly-ubiquitination does not lead to protein degradation by the proteasome.  Mediates transcriptional activation of target genes.  Required for postreplication repair of UV-damaged DNA and for adapting root developmental programs to suboptimal availability of iron.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 35, E2 ubiquitin-conjugating enzyme 35, Ubiquitin carrier protein 35.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: TBB6_BOVIN
Sequence: MREIVHIQAGQCGNQIGTKFWEVISDEHGIDPAGGYVGDSALQLERINVYYNESSSQKYVPRAALVDLEPGTMDSVRSGPFGQLFRPDNFIFGQTGAGNNWAKGHYTEGAELVDSVLDVVRKECEHCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGPMSMKEVDEQMLAIQNKNSSYFVEWIPNNVKVAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFSAMFRRKAFLHWFTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEGEEAFEDDEEEVNE
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:6504138, PubMed:2207090, PubMed:7704569).  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (PubMed:6504138, PubMed:2207090, PubMed:7704569).
What are the official names of this protein?
Tubulin beta-6 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: SLAPM_BREBN
Sequence: MKKVVNSVLASALALTVAPMAFAAEEAATTTAPKMDADMEKTVKRLEALGLVAGYGNGEYGVDKTITRAEFATLVVRARGLEQGAKLAQFSNTYTDVKSTDWFAGFVNVASGEEIVKGFPDKSFKPQNQVTYAEAVTMIVRALGYEPSVKGVWPNSMISKASELNIARSITTPNNAATRGDIFKMLDNALRVDLMEQVEFGTDIRHEITKETLLTKYLKVTVRDMEWAQEAGNDSEDLPLVTNVPAIGLGKIKANEVTLNGKDAGIGNTTYKVADGINANDFDGQHVQVWIKDDKEDVIVWMEGSTDQEVIMDRVGEFTLKGKTFEDPKDLSNSDLADLKLELDASEKSYRFNKNTKVTYNFTRFNDPVDGLKEIIKDNADGGFTFGAKVVLDNNNEIAYIHVIDDQSMNKEDEGVKYGSEVISKIDTDKKKITNRDNDKFNDLDGKEEGKDFLVFLNGKPAKFSDLKEGMVYSVYYADGDEDKLLVFATDTVVEGKVDKVVSRNNNDYRLTIGDKTYRVYEGATFSDDGNKDVQDIDKDHWDLVDSLDDETVKLYLDASGRVRHIETKDAIDDRKQKAIVTRSATFNTSKDTWDFRVLTQKGKEITVSLEAKNIYDFDGKNFSRDNKNQDDLEDILVPSKDKDTLLLEVTLDADGKPGKVEFLKPVKVEQESGKAWDDLADEDDDMVGDYEVTDKTAVFNMTGKLEESSKRKELKNAKTAKFKDVADENDLSVIYTVNDKDEVEAIFVVEGDGLTGDAHYGQVIDFGRKGGKDTIRVWEKDGDKVVEKEYKLDGDQDDLKDEDIRRNDFIAFTVDSNDEVVVDDVVEVVNKNAKGMLAEVTDEKGMKDANIDKMVVGLVSDVSKDTITYKDADDNKKKASIKSATVYFDLYDDFGEADGVNEGDYVVMIDSGDISGTKYDYVLIVSDAKTVRKDKLEDDAEAFLKQEPSEKPDPDTKWDALPSKVEGKFTSAGPVKLYRATVELNSKVKAEDVDAIEFYFNGKKVEPSLLNFKDGVITIGYNTEDKVTSSKIKVTNKNGKDSDEATVTFVEA
What is the function of this protein?
The middle wall protein binds to peptidoglycan and to the outer cell wall protein.
What are the official names of this protein?
Middle cell wall protein, MWP.
What are the subcellular locations of this protein?
Secreted, cell wall, S-layer. Note=This bacterium is covered by a S-layer with hexagonal symmetry.
Protein: PDXT_THEM4
Sequence: MKIGVSGIQGDFREHKVMLERLGVEVLVVRKPEELDEVEGLVIPGGESTTMIRIMKMVNLYEKLKEKILSGFPVFGTCAGMILLSKEVVNFKQDSLGVIDIKVERNAYGRQVDSFETDVEIKGFDKSYRAIFIRAPKVVDYGNDVEVLSIYEDAPILLRQKKVLVASFHPELTEDTRVHEYFLSMVK
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: PEPT_STAES
Sequence: MKKQIIERLTRYVKIDTQSNPDSKTTPSTNKQWDLLNLLEEELQSLGLKTDMDEHGYLFATLESNINYNVPTVGFLAHVDTSPDFNASHVNPQIIEAYNGQPIKLGESQRILDPDVFPELNKVVGHTLMVTDGTSLLGADDKAGVVEIMEGIKYLIDHPDIKHGTIRVGFTPDEEIGRGPHQFDVSRFNADFAYTMDGSQLGELQFESFNAAEVTVTCHGVNVHPGSAKNAMVNAISLGQQFNSLLPSHEVPERTEGYEGFYHLMNFTGNVEKATLQYIIRDHDKEQFELRKKRMMEIRDDINVHYNHFPIKVDVHDQYFNMAEKIEPLKHIIDIPKRVFEALDIVPNTEPIRGGTDGSQLSFMGLPTPNIFTGCGNFHGPFEYASIDVMEKAVHVVVGIAQEVANSHQSYK
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ST1E3_RAT
Sequence: METSMPEYYDVFGDFHGFLMDKRFTKYWEDVETFLARPDDLLIVTYPKSGSTWISEIVDMIYKEGDVEKCKEDALFNRIPDLECRNEDLINGIKQLKEKESPRIVKTHLPAKLLPASFWEKNCKIIYLCRNAKDVVVSYYYFFLIMKSYPNPKSFSEFVEKFMEGQVPYGSWYDHVKSWWEKSKNSRVLFMFYEDMKEDIRREVVKLIEFLERDPSAELVDRIIQHTSFQEMKNNPCTNYSMLPETMIDLKVSPFMRKGIVGDWKNHFPEALRERFEEHYQQQMKDCPVKFRAEL
What is the function of this protein?
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone (PubMed:7857871).  May play a role in the regulation of estrogen receptor activity by metabolizing free estradiol (By similarity).
What are the official names of this protein?
Estrogen sulfotransferase, isoform 3, EST-3, Estrone sulfotransferase, Sulfotransferase, estrogen-preferring.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_CALS8
Sequence: MRKLFTSESVTEGHPDKICDQISDAVLDAILEKDPYARVACEVAVTTGLVLVMGEITTKCYVDIPKIARDTIREIGYTRAKYGFDADTCAVITSIDEQSPDIAMGVDKALEAKLGEMTDDEIEAIGAGDQGMMFGFACDETPVLMPMPIYLAHKLARRLAYVRKGGILPYLRPDGKTQVTVEYEDDRPIRVDTIVVSTQHSPEVTHAQIEADVIEHVIKPIIPEGMLDKNTKIYINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSATYAARYVAKNIVAAGLAKKCEVQLSYAIGVARPLSIRVDTFGTGKIDDEKIAEIVKRVFDLRPAAIIRDLDLRRPIYKKVAAYGHFGREDLDLPWERTDKVDIILKEAQNI
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y276_HAEIN
Sequence: MISLKNFGLLFWKRFSENKLNQVAGALTYSTMLAMVPLVMVIFSIFSAFPVFNEVTGELKEMIFTNFAPSASDMVGEYIDQFVSNSKKMSAVGIVSLIAVALMLINNIDRTLNSIWHNSQSRSPLSSFAIYWMILTLGPLIIGVSIGISSYIKIMFEQSEHLSLGLKLLSFVPFLFTWFIFTLIYTVVPNKKVKIKHSAYGAFLAAIFFTLGKQAFTWYIVTFPSYQLIYGAMATLPIMLLWIQISWLVVLVGAQLASTLDEIGEQIEQ
What are the official names of this protein?
UPF0761 membrane protein HI_0276.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.