PharMolix/UniProtQA huggingface dataset:
Protein: KGUA_PROMP
Sequence: MKNLKKLIIITGPSGVGKGTVIKELLDRNKDIWLSISATTRNPRVGEKDDLNYYFIGEERFKDMIDKKEFLEWAQFAGNYYGTPLSTVNEKIEKGFIVLLEIEVEGAKQIKEKFPESLSIFLLPPSKEELEKRIRNRGTEKEEAIDRRLSRANYEIASSNQFDFVLTNHDVDETVKEVLKIIKS
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_SHIB3
Sequence: MLNNAMSVVILAAGKGTRMYSDLPKVLHTLAGKAMVQHVIDAANELGAAHVHLVYGHGGDLLKQALKDDNLNWVLQAEQLGTGHAMQQAAPFFADDEDILMLYGDVPLISVETLQRLRDAKPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDATDEQRQIQEINTGILIANGADMKRWLAKLTNNNAQGEYYITDIIALAYQEGREIVAVHPQRLSEVEGVNNRLQLSRLERVYQSEQAEKLLLAGVMLRDPARFYLRGTLTHGRDVEIDTNVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDVNLAAACTIGPFARLRPGAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTTVTRNVGENALAISRVPQTQKEGWRRPVKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PXPA_ECOHS
Sequence: MKIDLNADLGEGCASDAELLTLVSSANIACGFHAGDAQTMQACVREAIKNGVAIGAHPSFPDRENFGRSAMQLPPETVYAQTLYQIGALATIARAQGGVMRHVKPHGMLYNQAAKEAQLADAIARAVYACDPALVLVGLAGSELIRAGKQYGLTTREEVFADRGYQADGSLVPRSQPGALIENEEQALAQTLEMVQHGRVKSITGEWATVTAQTVCLHGDGEHALAFARRLRSTFAEKEIVVAA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: ACPS_MYCPA
Sequence: MGIVGVGIDLVSIPEFAEQVDQPGTVFSETFTPGERRDASDKSSSAARHLAARWAAKEAVIKAWSGSRFAQRPVLREDIHRDIEVVTDMWGRPRVRLSGDIAKHLADVTIHVSLTHEKDTAAAVAILETP
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_VIBVU
Sequence: MAENQYYGTGRRKSSAARVFIKPGSGNIVINKRALEEYFGRPTSCMVVKQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRPALRAAGYVTRDARCVERKKVGLRKARRRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: TVP38_VANPO
Sequence: MADNYEARTSSHYDNNATEFDDYFNEFDTGIGLGPDDEDDFLDIYNLSPRQRVVYQFRRTVNQFLSQYYALEPWQRILLAIGGGLIGILALLMLIFHNKILHKLVEMSNDLKEKWSTPIVLVTLIFFVAFPPMIGFSLLSTTTGLIYGISFKGWVILAIGAVTGSICSFALFKTILHSRAEKLIQMNRRFAAFASILQENNSYWILALLRLCPFPYSLTNGAVGAVYGVSIKNFAIGNIITTPKLLIYLFIGSRIKNMGETESSASKIFDLVSILLTVLALGLTAWVLYFKTQKRYQQLQDQSTINTSNDLDIDQNFEI
What is the function of this protein?
Golgi membrane protein involved in vesicular trafficking and spindle migration.
What are the official names of this protein?
Golgi apparatus membrane protein TVP38.
What is the protein family that this protein belongs to?
Belongs to the TVP38/TMEM64 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: NXPE2_HUMAN
Sequence: MVEKILIHRILTLFPNAIARKLLLMLTFILIFWIIYLASKDHTKFSFNLENHIILNQGNIFKKYSHSETPLCPAVSPKETELRIKDIMEKLDQQIPPRPFTHVNTTTSATHSTATILNPQDTYCRGDQLDILLEVRDHLGHRKQYGGDFLRARMYSTALMAGASGKVTDFNNGTYLVSFTLFWEGQVSLSLLLIHPSEGVSALWRARNQGCDRIIFTGLFANRSSNVFTECGLTLNTNAELCQYMDDRDQEAFYCVRPQHMPCEALTHMTTRTRNISYLSKEEWRLFHRSNIGVEMMKNFTPIEVIPCNKSENIKKNCQIGMKTPFPSGYTLKKMWITAFCKQIKFNETKNINDCLERKLIYLMGDSTLHQWIYYLQKAVKTLKYFDHHGAGIFKTHVLLDVERHILIQWKKHGHPFVTKKLFSVKDENYIPREIDQVAGDKNTAIVITLGQHFRPFPINIFIRRAINIQKAIERLFLRSPETKVILKTENTREIEQNAEMFSDFHGYIQNLIIRDIFVDLNVGIIDAWDMTIAYCTNNAHPPDYVIQNQIGMFLNYIC
What are the official names of this protein?
NXPE family member 2, Protein FAM55B.
What is the protein family that this protein belongs to?
Belongs to the NXPE family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CRS5_YEAS8
Sequence: MTVKICDCEGECCKDSCHCGSTCLPSCSGGEKCKCDHSTGSPQCKSCGEKCKCETTCTCEKSKCNCEKC
What is the function of this protein?
Critical role in copper (specific) homeostasis and detoxification.  May protect by directly chelating and sequestering copper ions (By similarity).
What are the official names of this protein?
Metallothionein-like protein CRS5.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 13 family.
Protein: PDE6D_DROGR
Sequence: MGSDDLSTGDKIQKGFQINYMILRDADTGKVIWQENKDFSAPDLEHEARVPVKILDMRAVSREINFSTIEAMENFRLDQKVLFKGRIMEEWFFEMGFVGANTTNTWQSTIEAAPESQMMPAKVLNGNVTIQTSFYDNETLITKSVVRLYYI
What are the official names of this protein?
Probable cGMP 3',5'-cyclic phosphodiesterase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the PDE6D/unc-119 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: LYSM4_ARTBC
Sequence: MGQLKQLAGILALASPAIAAFSVYALHDPDALKASLGVTSECLSALNYTVECDGPSAVRATKNSDNDPWSMDDLTTLCTDGCSKSLSTWFDAVEQKCEGEEVTINGLVVDPKAFPMKYISGYDLACLRDSNDNWCFYEAQDWDSGVFTSWDKKQPDACSGENPPADCDKKGSEEDVDTLYVTNSYDKELYCSECFMLLWRQRIESPVFPQGNLLDHFTKQFSKLEAACSTKLPLTTPAPTVVLGAKDTLPPATGYHTDGSTVFRYSSPPAPTITTEEPIAKRTAAPRAMKTFYTPATPDRTPQLGAMAPCGKYYNVVAGDTCASISSEFEVTMDELLTYNPELHPNCENLWANFAICVAPVSPNPMTVDGSCGENNAGATCDGSPFGSCCNNEGRCVPCGPEATAAPDAPDAQGQTVHDDEPPEEPHIEEPPKDIPAGDDDDRKKAKLPLPSGKYPLPSNSTMISKDGSCNEYISCVGSPFGVCCSTSGWCGYGKPWCGVGNCVSGYCDTEDKASGKPQ
What is the function of this protein?
Might have a role in sequestration of chitin oligosaccharides (breakdown products of fungal cell walls that are released during invasion and act as triggers of host immunity) to dampen host defense.
What are the official names of this protein?
LysM domain-containing protein ARB_03442.
What are the subcellular locations of this protein?
Secreted.
Protein: OBG_STRT1
Sequence: MSMFLDTAKISVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGGSVIFKVDEGLRTLMDFRYNRKFKAKNGEKGMTKGMHGRGAEDLIVSIPPGTTVRDAETGKVITDMVEDGQEFVVAHGGRGGRGNIRFATPRNPAPEIAENGEPGEERELQLELKILADVGLVGFPSVGKSTILSVVTAAKPKIGAYHFTTIVPNLGMVRTKSGESFAMADLPGLIEGASQGVGLGTQFLRHIERTRVILHVIDMSASEGRDPYEDYLQINKELETYNLRLMERPQIIVANKMDMPEAEENLKEFKEKLAANYDEFDELPQIFPISSLAHQGLENLLEATAELLDQTDEFLLYNEDDMEQEEVYYGFNEEERPFEISRDDDASWVLSGEKLEKLFVMTNMERDESIMKFARQLRGMGVDEALRERGAKDGDIVRIGNFEFEFVD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YVAE_BACSU
Sequence: MNWVFLCLAILFEVAGTVSMKLSSGFTKLIPSLLLIFFYGGSLFFLTLTLKSIDVSVAYAVWSGMGIVLITVVGFLFFQEHVSVMKVISIGLIIAGVVSLNLIEHVAVSEPVHKSGQYK
What are the official names of this protein?
Uncharacterized membrane protein YvaE.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: XP1_XENLA
Sequence: MNYKVFCLVAIALIVGSIGSANGQAAFTEEQCSVERLARVNCGYSGITPQECTKQGCCFDSTIQDAPWCFYPRATPEY
What is the function of this protein?
May act as a growth factor.
What are the official names of this protein?
Putative gastrointestinal growth factor xP1.
What are the subcellular locations of this protein?
Secreted.
Protein: RNC_ECOUT
Sequence: MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLGDSILSYVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFELGECLRLGPGELKSGGFRRESILADTVEALIGGVFLDSDIQTVEKLILNWYQTRLDEISPGDKQKDPKTRLQEYLQGRHLPLPTYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQALKKLELE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CT204_MOUSE
Sequence: MVRPKLAFYILPLLLAFLGSALGWPGSQSCSVQEVLRHYQAVIFQDLQTAMQWAGLGVQHTQPGSRHHRFIQKNLTGAGGGQGQPGTSCDAQKESSILLSIESLGQTLLGSVAGVPHNALEKAAWTVAVRTEAVMRRHCGTSYRIQQPRKHAVQLRNSRRRLLLRALYAVATCWEKLFALSAMATGEF
What are the official names of this protein?
Uncharacterized protein C20orf204 homolog.
Protein: RL27_BURPS
Sequence: MAHKKAGGSSRNGRDSESKRLGVKVYGGQAINAGGIIVRQRGTRMHAGENVGMGKDHTLFALVDGHVKFTTKGAAKKHTVVVVPAAA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: SO3A1_BOVIN
Sequence: MQAKKPGGSSGGGRSGELQGDEAQRNKKKKKKVSCFSNIKIFLVSECALMLAQGTVGAYLVSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEIRWGAEGRDVCAANGSGGDQGPDPDLICRSRTATNMMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSSVLMFGFPQSLPPHSDPALESEQAMLPEREYERPKPSNGVLRHPLEPDSSASCFQQLRVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPYGNSSTPGSALDPYSSCNKNCECQTDSFTPVCGADGITYLSACFAGCNSTNLTGCACLMTIPPENATVIPGKCPSPGCQEAFLTFLCVMCVCSMIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWSTFCGEQGACALYDNVAYRYLYVSIAIALKSFAFLLYTTTWQCLRKNYKRYIKNHEGGLSTSEFFASTLTLDNLGRDPVPANQTHRTKFIYNLEDHEWCENMESVL
What is the function of this protein?
Mediates the Na(+)-independent transport of organic anions such as prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II, BQ-123 and vasopressin.  Also displays a low transport activity of estrone 3-sulfate.  Shows a pH-sensitive substrate specificity towards T4 and estrone 3-sulfate which may be ascribed to the protonation state of the binding site and leads to a stimulation of substrate transport in an acidic microenvironment.  Hydrogencarbonate/HCO3(-) acts as the probable counteranion that exchanges for organic anions.  May contribute to regulate the transport of organic compounds in testes across the blood-testis-barrier.
What are the official names of this protein?
Solute carrier organic anion transporter family member 3A1, Organic anion-transporting polypeptide D, OATP-D.
What is the protein family that this protein belongs to?
Belongs to the organo anion transporter (TC 2.A.60) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PLSY3_DEHMC
Sequence: MLIAKLLLVVIVSYILGSIPFGYLVSHRGSKIDIRSFGSGRTGATNVLRTMGRKAALLVASLDVIKGASAVAFAGLVIGTEALAFGTNGMALLFAQVLAGLAAVAGHIWPVFLKFRGGRGVATFFGGMIALCPVAAIFGGEVLIIGAGLSGFASLGSITGVVGAYALLVPLTLISGFPTEYMIYAVIGSLLITIMHRDNIKRLLAGKERKLNEKAR
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase 3, Acyl-PO4 G3P acyltransferase 3, Acyl-phosphate--glycerol-3-phosphate acyltransferase 3, G3P acyltransferase 3, GPAT 3, Lysophosphatidic acid synthase 3, LPA synthase 3.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OR4K2_HUMAN
Sequence: MDVGNKSTMSEFVLLGLSNSWELQMFFFMVFSLLYVATMVGNSLIVITVIVDPHLHSPMYFLLTNLSIIDMSLASFATPKMITDYLTGHKTISFDGCLTQIFFLHLFTGTEIILLMAMSFDRYIAICKPLHYASVISPQVCVALVVASWIMGVMHSMSQVIFALTLPFCGPYEVDSFFCDLPVVFQLACVDTYVLGLFMISTSGIIALSCFIVLFNSYVIVLVTVKHHSSRGSSKALSTCTAHFIVVFLFFGPCIFIYMWPLSSFLTDKILSVFYTIFTPTLNPIIYTLRNQEVKIAMRKLKNRFLNFNKAMPS
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 4K2, Olfactory receptor OR14-15.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AGRB2_HUMAN
Sequence: MENTGWMGKGHRMTPACPLLLSVILSLRLATAFDPAPSACSALASGVLYGAFSLQDLFPTIASGCSWTLENPDPTKYSLYLRFNRQEQVCAHFAPRLLPLDHYLVNFTCLRPSPEEAVAQAESEVGRPEEEEAEAAAGLELCSGSGPFTFLHFDKNFVQLCLSAEPSEAPRLLAPAALAFRFVEVLLINNNNSSQFTCGVLCRWSEECGRAAGRACGFAQPGCSCPGEAGAGSTTTTSPGPPAAHTLSNALVPGGPAPPAEADLHSGSSNDLFTTEMRYGEEPEEEPKVKTQWPRSADEPGLYMAQTGDPAAEEWSPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNNSATCPVHGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQHGGKACEGPELQTKLCSMAACPVEGQWLEWGPWGPCSTSCANGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPATDSKWGPWNAWSLCSKTCDTGWQRRFRMCQATGTQGYPCEGTGEEVKPCSEKRCPAFHEMCRDEYVMLMTWKKAAAGEIIYNKCPPNASGSASRRCLLSAQGVAYWGLPSFARCISHEYRYLYLSLREHLAKGQRMLAGEGMSQVVRSLQELLARRTYYSGDLLFSVDILRNVTDTFKRATYVPSADDVQRFFQVVSFMVDAENKEKWDDAQQVSPGSVHLLRVVEDFIHLVGDALKAFQSSLIVTDNLVISIQREPVSAVSSDITFPMRGRRGMKDWVRHSEDRLFLPKEVLSLSSPGKPATSGAAGSPGRGRGPGTVPPGPGHSHQRLLPADPDESSYFVIGAVLYRTLGLILPPPRPPLAVTSRVMTVTVRPPTQPPAEPLITVELSYIINGTTDPHCASWDYSRADASSGDWDTENCQTLETQAAHTRCQCQHLSTFAVLAQPPKDLTLELAGSPSVPLVIGCAVSCMALLTLLAIYAAFWRFIKSERSIILLNFCLSILASNILILVGQSRVLSKGVCTMTAAFLHFFFLSSFCWVLTEAWQSYLAVIGRMRTRLVRKRFLCLGWGLPALVVAVSVGFTRTKGYGTSSYCWLSLEGGLLYAFVGPAAVIVLVNMLIGIIVFNKLMARDGISDKSKKQRAGSERCPWASLLLPCSACGAVPSPLLSSASARNAMASLWSSCVVLPLLALTWMSAVLAMTDRRSVLFQALFAVFNSAQGFVITAVHCFLRREVQDVVKCQMGVCRADESEDSPDSCKNGQLQILSDFEKDVDLACQTVLFKEVNTCNPSTITGTLSRLSLDEDEEPKSCLVGPEGSLSFSPLPGNILVPMAASPGLGEPPPPQEANPVYMCGEGGLRQLDLTWLRPTEPGSEGDYMVLPRRTLSLQPGGGGGGGEDAPRARPEGTPRRAAKTVAHTEGYPSFLSVDHSGLGLGPAYGSLQNPYGMTFQPPPPTPSARQVPEPGERSRTMPRTVPGSTMKMGSLERKKLRYSDLDFEKVMHTRKRHSELYHELNQKFHTFDRYRSQSTAKREKRWSVSSGGAAERSVCTDKPSPGERPSLSQHRRHQSWSTFKSMTLGSLPPKPRERLTLHRAAAWEPTEPPDGDFQTEV
What is the function of this protein?
Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions.  Activates NFAT-signaling pathway, a transcription factor, via the G-protein GNAZ (PubMed:20367554, PubMed:28891236).  Involved in angiogenesis inhibition (By similarity).
What are the official names of this protein?
Adhesion G protein-coupled receptor B2, Brain-specific angiogenesis inhibitor 2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNZ_LACLM
Sequence: MEIQFLGTGAGQPSKSRNTQAIALKMLDERNEIWLFDCGEASQHQILNTAIKPRKITKIFITHLHGDHIFGLPGFLSSRSFQSSDEQTDLDLYGPVGIKEFVLAGLRISGSHLGYRINFHEIDSAGKIFEDDSFEVYTDLLDHTIFCLGYRVVEKNRVGELDANALKEAGLPFGPLFGKIKKGEVVDYDGKTFDPKDYIGADKVGKIVTILGDTRKTNTAVRLAWQADLLVHEATYEAAESKMARAHGHSTTKQAADVAKEAGVNRLLLTHISARYVGPLVGQLVREAQDVHANTFVAKDLYEEKIG
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: FMT_ECO45
Sequence: MSESLRIIFAGTPDFAARHLDALLSSGHNIVGVFTQPDRPAGRGKKLMPSPVKVLAEDKGLPVFQPVSLRPQENQQLVADLQADVMVVVAYGLILPKAVLEMPRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLSCPITAEDTSGTLYDKLAELGPQGLITTLKQLADGTAKPEVQDETLVTYAEKLSKEEARIDWSLSAAQLERCIRAFNPWPMSWLEIEGQPVKVWKASVIDTTTKAAPGTILEANKQGIQVATGDGILNLLSMQPAGKKAMSVQDLLNSRREWFVPGNRLA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: Y1533_SACS2
Sequence: MVFYHRQGELPKKRHTVFMKDGKLMREEVFGLNGFNGRYSLLYHLNPPTRIMKLGEWKSNTIGEWKDAEYRHHKLSTSKLRKSSDVFLDRIALIFNDNLIISFSKVDEGDTKLFYRNADFDEIYYVHSGEILFKSVFGEIEVKEGDYLVIPRGTTYTLSFKKNAELFIIEGKQIEVPKDYRNEYGQLVEGSFYYNRDLKLPVLRTYDENGNYKLVIKTVNGFQLVELDTHPFDVVGWDGYLYPFALSVYDLEPITGKLHQPPTAYTTFAADDFVVCTFVPRLFDYHPQSVPISYYHNNIDAEEIIFYSSGQFMSRRGINKGDITLHRGGHIHGPQPSAVEASLNKRGTYNDEVAIMVETQKRVKVSIYAKEIDDPTYPLSWYTS
What are the official names of this protein?
Putative dioxygenase SSO1533.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: SSRP_CORDI
Sequence: MAKKKKAKNSNPVIASNRKARHDYKILDTFECGIVLLGTEIKSIREGKVSLTDSFATIDEGEAWIRNLNIPIYSRGSWTNHSPMRTRKLLLHRREIDSLMGKVRDGNKTLVPLSLYFKEGRLKVELGLAQGKQDYDKRQDIKRRTEEREVVRDLGRRVKGIHA
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: LTX2C_LACTA
Sequence: MKVLVITALCFILLQNVLGEDTYEDLQNYIENLINENQDEARECVPLENDCTKLKYSNPCCKDEKKKYQYKCSCIVDKTEQCTCQRKETVEKMMKGMKYIKNLGKKIG
What is the function of this protein?
Insect toxin.
What are the official names of this protein?
Latartoxin-2c, LtTx-2c.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 11 (latartoxin) subfamily.
Protein: CYSI_THIRO
Sequence: MSAPIHENERIKARSNCLRGTLRESLADTLTGAISPEDTQISKFHGFYQQDHRDRRQARPEQYLEPYFGFMLRAPLPGGVCTPAQWLAIDGMGRELGGGSLRLTTRQSFQYHGILKRDIASVIRGINAVMIDSIGGCGDVNRNVLCNPNPVESALHREVYDWAKRISEHLLPRTRAYHEIWLDGEQVGGGEDVEPIYGRTYLPRKFKTAVGVPPHNDVDVYANDLGFAAVADGSRLIGFNVSAGGTGRNTGIPATFPRLADVLGFVEPERTLAVAEAVVTTQRHFGDRLDRTQARLKYTIERMGLDAFRDEVERRAGIRFAPARPIGFTDQGDRTAWVRGQDGRWHLTLYIESGRLIDGPGQSSMQGLREIARIHQGDFRITPNQNLIVARVPEPGKSEIEALARKYGLLDKGIALRLNGMSCVALPTCPLAMAEAERYYPDFLAQVERLTRKHGLAEQEIVTRMTGCPNGCARPYLAELALVGKGPGRYNLMLGGNGRRYRLNRLYRENLDEAAILAEIDTLLGRYAACRQPGERFGDYLIRDGIVRPVVNPAEDFHE
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: RS16_MICAN
Sequence: MIKLRLKRFGKKREASYRIVAAVSTSRRDGRPLEELGFYNPRTDEVRLDEEGIIRRLQQGAQPTDTVRSILTKQKIFEKINA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: KDSB_ECO27
Sequence: MSFVVIIPARYASTRLPGKPLVDINGKPMIVHVLERARESGAERIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCAFSDDTVIVNVQGDEPMIPATIIRQVADNLAQRQVGMATLAVPIHNAEEAFNPNAVKVVLDAEGYALYFSRATIPWDRDRFVKDLETVGDNFLRHLGIYGYRAGFIRRYVTWQPSPLEHIEMLEQLRVLWYGEKIHVAVAQEVPGTGVDTPEDLKRVRAEMR
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPLA_HUMAN
Sequence: MEKVQYLTRSAIRRASTIEMPQQARQKLQNLFINFCLILICLLLICIIVMLL
What is the function of this protein?
Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+) (PubMed:28890335).  Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2.  Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle.  The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.  ATP2A2 inhibition is alleviated by PLN phosphorylation.  Controls intracellular Ca(2+) levels in elongated spermatids.  May play a role in germ cell differentiation (By similarity).
What are the official names of this protein?
Cardiac phospholamban, PLB.
What is the protein family that this protein belongs to?
Belongs to the phospholamban family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Sarcoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. Membrane; Single-pass membrane protein. Note=Colocalizes with HAX1 at the endoplasmic reticulum (PubMed:17241641). Colocalizes with DMPK a the sarcoplasmic reticulum (PubMed:15598648).
Protein: PSAC_NICTO
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLWHETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.