PharMolix/UniProtQA huggingface dataset:
Protein: PANB_STAAE
Sequence: MKTVSQLIDMKQKQTKISMVTAYDFPSAKQVEAAGIDMILVGDSLGMTVLGYESIVQVTLADMIHHGRAVRRGAPNTFVVVDMPIGAVGISMTQDLNHALKLYQETNANAIKAEGAHITPFIEKATAIGIPVVAHLGLTPQSVGVMGYKLQGATKEAAEQLILDAKNVEQAGAVALVLEAIPNDLAEEISKHLTIPVIGIGAGKGTDGQVLVYHDMLNYGVEHKAKFVKQFADFSVGVDGLKQYDQEVKSGAFPSEEYTYKKKIMNEVNNND
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLX4_AJECN
Sequence: MDNTAITSQSSSTPLVCSVTPIIVGSPPSPANVIELSSPSTPPTPLTLLASLSETPSRKTTNPDTNGENTICHGVRQVRRVPRNNPVTGPSKEHKQRTRSPKTTTRREIKIVEGDRLIVGHDKREKKGETTKRMKKRDGVADKKLYARVSKVKSSENLDLDAKIPSSKVCNNTLPLVGDDMDNGSSELKLEQAIKRRHDWTPTREVTTPVVDVAELHSSPCGKAVTRMHGVGTLLSDYGFSGVVETSLGTKSESFRNAPTTKRPMELQKFSTVPAIPTPTESSTTEDVQGSSSKQQRVKAKKPQKGKLTTITSHATAKYCVADQTVDLDYIQNVAPKSPRRKNISNRPSGTKHSNSGRGKSSTLKNDNGRPVFRVVPPLEAFKSFEGQELLFGTSSQLERGYPEYPCDETQDTQNSPSNSAAVSELAVPYRISSEGKDLGSSLFGLSGSKNLWSASARDLTGAVFEGDEIDFQGASMGLSVLATKSRCHPGNRGPPRRNLVDVDNVPDKKLDIDTTEGENGNHSSVADNIVDRENLNPKISANTSETNLECAPQNKPAFSRFTTSELAKKVAAYGFKPIKSRDNMISLLEKCWETQSKTLILESKPNQGTDDARKNGFRKENHSDVRVRPDSATLANRRSPKKQQAKALSKFQEPNNFLPIENSTTTASMLPIISSHTILINDDQLSDSVGETVSFLPSLDHNGNGTTIQENMLEIKSPATPNARRSRQGSSSASFSIEPPSLASQITKAIKSQPRTRAFNGLKQPTWYEKILMYDPIQLEDLAAWLNTDGFGRIGEDREVGPGVVREWCESKGVCCVWKKQVSGRSHYLPMVS
What is the function of this protein?
Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit SLX4.
What is the protein family that this protein belongs to?
Belongs to the SLX4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BETB_BURP0
Sequence: MSVYGLQRLYIAGAHADATSGKTFDTFDPATGELLARVQQASADDVDRAVASAREGQREWAAMTAMQRSRILRRAVELLRERNDALAELEMRDTGKPIAETRAVDIVTGADVIEYYAGLATAIEGLQVPLRPESFVYTRREPLGVCAGIGAWNYPIQIACWKSAPALAAGNAMIFKPSEVTPLSALKLAEIYTEAGVPAGVFNVVQGDGSVGALLSAHPGIAKVSFTGGVETGKKVMSLAGASSLKEVTMELGGKSPLIVFDDADLDRAADIAVTANFFSAGQVCTNGTRVFVQQAVKDAFVERVLARVARIRVGKPSDSDTNFGPLASAAQLDKVLGYIDSGKAEGAKLLAGGARLVNDHFASGQYVAPTVFGDCRDDMRIVREEIFGPVMSILSFETEDEAIARANATDYGLAAGVVTENLSRAHRAIHRLEAGICWINTWGESPAEMPVGGYKQSGVGRENGITTLEHYTRIKSVQVELGRYQPVF
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: NDK_CHLP8
Sequence: MERTLTILKPDCVRKQLIGAVTDKIERAGFRIVAMKKTRLTKETAGAFYAVHKERPFYGELVEFMSSGPCVPMILEKENAVADFRTLIGATDPAEAAEGTVRKLYADSKGENIVHGSDSAENAAIEGAFFFAAEEVVRVD
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAC_PANGI
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVSLWHETTRSMGLGY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: EMB30_CAEEL
Sequence: MDFSIVKTQILNNRRTFRTPFKVSSMCFSSQNDLIALGSKTGEILLKRTSWKMIWKTNINMIQAVGTECKLDSSVSALHFSPDGRFLAAATSKGIIHLLDVETGKVRFSVKAASEKIAKLHWNCVREKPFISNLGEFTTRIKNVEAIEGAIELAETTPNISQEEIAFVYQRLDEDGSSFKHEDAHKESLERTLISTETFRESLQNTILLATDDMDSKIIVLVAGVFPYMEIDISDTLLQYNQSLLMLYDMHYSSAFGGVSFLATTYGPFLDCKQNELKPPGAEPKKDGQGCHTLLFNVKLNINSSLWDTALRYIRLLFGFNLYSISLETTKRNWEEQIDNLHSLFDTKTKAVKIGNVLLEMLLSGSTDAAGEAFLERGLGTDGLDKIELFATKHMPEVCRIARGQLSTSARNLCFQRCEFSTSLSRYAKFIQLKDDDSFLYDEDPPAYLSESNIWLNTLEEKINILDMKTRHLGIQCLTMMQELGHLVKWISMTKPFAKTMKVNALMKIKRMNIAKILLYIVRNFIPDPEAVKDIENRLFNLKELVSKQKKKDLEDKFDEVEYLYRLERIAEVERKKLIETFHEKFRFADLDDDDLTPLLFQELDHPIDIFTDSMMEQNDSSPFLEEDEGEPEQEEQKPDEEPEPEGEPQPACDLDRVGSFFEKELSQKALEVLPKCDETFDCVLNERGSRMNSIEIQKMGILRVLEDLAATLSSPQKIHCDKAGNQKKLEVSFIYEITSTPTHQGYQDAKISSVTPSYYKRHPFNQLSGMGRSIQVSVLQKNEFSSIVIVPTSDVLPEDENEVNDHVEKLKRCYEFEKIDVTVDKSSAENRPPGETDAMEVDSNELRIDVDLGPVVPEYDTLIELSQVHPLHHGELVLLGKFTSAQEGTGVMSQMMRSISSYPHEIPEDKDVFAKNSSEDGSSEIPIETLIIHPTIQLAAYLHDDGSKITIGDMKPEVPPIADYEEKTVRKTFRDYQRRRERYREDMGVMNMNDVQYDVLVQEAMDSGRDLTDNGESDEDEEDDDI
What is the function of this protein?
Probable component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle (By similarity).  The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins (By similarity).  Developmental role in early embryogenesis and the metaphase to anaphase transition in oocyte and spermatocyte meiosis and mitosis in somatic and germ cells (PubMed:10749938, PubMed:12498686, PubMed:11134076, PubMed:17237515).  Required for embryonic anterior-posterior axis formation (PubMed:11832245).  Negatively regulates ify-1 protein levels during meiosis I (PubMed:12498686).  Plays a role in regulating the abundance of glr-1 receptors in postmitotic neurons, which may in turn control animal locomotion (PubMed:15556870).  Involved in regulating GABA neurotransmitter release at neuromuscular junctions in GABA motor neurons (PubMed:24321454).
What are the official names of this protein?
Abnormal embryogenesis protein 30.
What is the protein family that this protein belongs to?
Belongs to the APC4 family.
Protein: NUCL_XENLA
Sequence: MVKLAKGAKTQAKPKKAAPPPPKDMEDSEEEEDMEEDDSSDEEVEVPVKKTPAKKTATPAKATPGKAATPGKKGATPAKNGKQAKKQESEEEEDDSDEEAEDQKPIKNKPVAKKAVAKKEESEEDDDDEDESEEEKAVAKKPTPAKKPAGKKQESEEEDDEESEDEPMEVAPALKGKKTAQAAEEDDEEEDDDDEEDDDDEEEQQGSAKRKKEMPKTIPEAKKTKTDTASEGLSIFIGNLNSTKEFDELKDALREFFSKKNLTIQDIRIGNSKKFGYVDFSSEEEVEKALKLTGKKILGTEVKIEKAMAFDKNKTAENKKERDSRTLFVKNIPYSTTVEELQEIFENAKDIRIPTGKDGSNKGIAYVEFSNEDEANKALEEKQGAEIEGRSIFVDFTGEKSQNSGNKKGPEGDSKVLVVNNLSYSATEDSLREVFEKATSIRIPQNQGRAKGFAFIEFSSAEDAKDAMDSCNNTEIEGRSIRLEFSQGGGPQGGGRGGSAQSKTLFVRGLSEDTTEETLKEAFDGSVNARIVTDRDTGASKGFGFVDFSTAEDAKAAKEAMEDGEIDGNKVTLDFAKPKGDSQRGGRGGFGRGGGFRGGRGGRGGGGGRGFGGRGGGRGRGGFGGRGGGGFRGGQGGGFRGGQGKKMRFDD
What is the function of this protein?
Nucleolin is the major nucleolar protein of growing eukaryotic cells.  It is found associated with intranucleolar chromatin and pre-ribosomal particles.  It induces chromatin decondensation by binding to histone H1.  It is thought to play a role in pre-rRNA transcription and ribosome assembly.
What are the official names of this protein?
Nucleolin, Protein C23.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CYB_DIPIS
Sequence: MTIMRKTHPLMKMVNHAFIDLPAPSNISGWWNFGSLLGLCLIIQIASGLFLAMHYTPDTTTAFSSVTHICRDVNYGWLIRYMHANGASLFFICLYLHIGRGMYYGSYSYMETWNIGIILLFLTMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLNRFFAFHFILPFIIAAMAMVHLLFLHETGSNNPLGIPSDCDKIPFHPYYTTKDFLGIVLLLAFFFTLVLFFPDLLGDPDNYSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVIALVLSILVLALLPHIQTAKQRSLMFRPISQFLFWLLVSDVFVLTWIGGQPVEPPFIIIGQIASLLYFTIILAFMPIAGLIENKMLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TAL_METPP
Sequence: MSSQLEQLKAYTTVVADTGDFKQIAAFAPRDATTNPSLILKAVSQPAYAPLLAQTAAAHRGQPLDAIVDRVLVRFGCEILNVVPGRVSTEVDARLSFDAAATVARAQRIMALYESEGIARERVLIKIAATWEGIQAAKALEHHGIHCNLTLLFAFCQAVACGESGVRLISPFVGRIHDWHKKAAGARWDEAANAGANDPGVKSVAQIWRYFRKFGIETEVMGASFRNTGQILALAGCDLLTISPELLAQLQASEATVMRALDVDAALHCDAKALSFNEASFRYALNEDAMATEKLAEGIRAFAVDAAQLDRLIQAL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTGA_XYLFM
Sequence: MYQWIQRDSDVHQRWIWCRRLLIVSLVSALMSVLQVIVFRFVDPPLSMTMVGRYLEAWSDRQWNFRLHYVWCDLEQIAPSVPISLVAAEDQRFPFHHGFDFDAIKNALGRHSRGGHLRGASTISQQVAKNLFLWSGRSFVRKGLEGWYTFWIELFWPKRRILEIYANIAEFGDGVYGVQAAARRYLGKGAADLDESDAAQLAAVLPSPRHYNIQHPGPYIRWRSSWIQRQAKQLGGSAYLDMH
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: OSTCN_CAMBA
Sequence: YLDHGLGAPAPYVDPLEPKREVCELNPDCDELADQMGFQEAYRRFYGTT
What is the function of this protein?
Constitutes 1-2% of the total bone protein.  It binds strongly to apatite and calcium (By similarity).
What are the official names of this protein?
Osteocalcin, Bone Gla protein, BGP, Gamma-carboxyglutamic acid-containing protein.
What is the protein family that this protein belongs to?
Belongs to the osteocalcin/matrix Gla protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: RR7_SACOF
Sequence: MSRRGTAEKRTAKSDPIFRNRLVNMVVNRIMKDGKKSLAYQILYRAVKKIQQKTETNPLLVLRQAIRRVTPNIGVKTRRNKKGSTRKVPIEIGSKQGRALAIRWLLEASQKRPGRNMAFKLSSELVDAAKGSGGAIRKKEATHRMAEANRALAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PRO_HTL1C
Sequence: MGQIFSRSASPIPRPPRGLAAHHWLNFLQAAYRLEPGPSSYDFHQLKKFLKIALETPVWICPINYSLLASLLPKGYPGRVNEILHILIQTQAQIPSRPAPPPPSSSTHDPPDSDPQIPPPYVEPTAPQVLPVMHPHGAPPNHRPWQMKDLQAIKQEVSQAAPGSPQFMQTIRLAVQQFDPTAKDLQDLLQYLCSSLVASLHHQQLDSLISEAETRGITGYNPLAGPLRVQANNPQQQGLRREYQQLWLAAFAALPGSAKDPSWASILQGLEEPYHAFVERLNIALDNGLPEGTPKDPILRSLAYSNANKECQKLLQARGHTNSPLGDMLRACQAWTPKDKTKVLVVQPKKPPPNQPCFRCGKAGHWSRDCTQPRPPPGPCPLCQDPTHWKRDCPRLKPTIPEPEPEEDALLLDLPADIPHPKNLHRGGGLTSPPTLQQVLPNQDPTSILPVIPLDPARRPVIKAQIDTQTSHPKTIEALLDTGADMTVLPIALFSSNTPLKNTSVLGAGGQTQDHFKLTSLPVLIRLPFRTTPIVLTSCLVDTKNNWAIIGRDALQQCQGVLYLPEAKRPPVILPIQAPAVLGLEHLPRPPEISQFPLNQNASRPCNTWSGRPWRQAISNPTPGQEITQYSQLKKPMEPGDSSTTCGPLTL
What is the function of this protein?
The aspartyl protease mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane.  Cleavages take place as an ordered, step-wise cascade to yield mature proteins.  This process is called maturation.  Displays maximal activity during the budding process just prior to particle release from the cell (Potential).  Cleaves the translation initiation factor eIF4G leading to the inhibition of host cap-dependent translation (By similarity).
What are the official names of this protein?
Gag-Pro polyprotein, Pr76Gag-Pro.
What are the subcellular locations of this protein?
[Matrix protein p19]: Virion. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p15-pro]: Virion.
Protein: CS12F_SYNPJ
Sequence: MGESVKAIKLKILDMFLDPECTKQDDNWRKDLSTMSRFCAEAGNMCLRDLYNYFSMPKEDRISSKDLYNAMYHKTKLLHPELPGKVANQIVNHAKDVWKRNAKLIYRNQISMPTYKITTAPIRLQNNIYKLIKNKNKYIIDVQLYSKEYSKDSGKGTHRYFLVAVRDSSTRMIFDRIMSKDHIDSSKSYTQGQLQIKKDHQGKWYCIIPYTFPTHETVLDPDKVMGVDLGVAKAVYWAFNSSYKRGCIDGGEIEHFRKMIRARRVSIQNQIKHSGDARKGHGRKRALKPIETLSEKEKNFRDTINHRYANRIVEAAIKQGCGTIQIENLEGIADTTGSKFLKNWPYYDLQTKIVNKAKEHGITVVAINPQYTSQRCSMCGYIEKTNRSSQAVFECKQCGYGSRTICINCRHVQVSGDVCEECGGIVKKENVNADYNAAKNISTPYIDQIIMEKCLELGIPYRSITCKECGHIQASGNTCEVCGSTNILKPKKIRKAK
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids (Probable).  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA), which requires a trans-encoded small RNA (tracrRNA), but not this protein (By similarity).  Recognizes a short motif in the CRISPR repeat sequences (the 5' PAM or protospacer adjacent motif, TTC in this organism) to help distinguish self versus nonself, as targets within the CRISPR locus do not have PAMs.  Has dsDNA endonuclease activity upon expression in E. coli of this protein, a mini CRISPR array and the probable tracrRNA.  Plasmid cleavage is centered around positions 24 base pairs 3' of PAM.  The mini system protects E. coli against transformation by foreign plasmids (PubMed:32246713).
What are the official names of this protein?
CRISPR-associated endodeoxyribonuclease Cas12f1, SpCas12f1, CRISPR-associated endonuclease C2c10.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endonuclease Cas12f family.
Protein: BFRB_NEIMA
Sequence: MKGDRLVIRELNKNLGLLLVTINQYFLHARILKNWGFEELGEHFFKQSIVEMKAADDLIERILFLEGLPNLQELGKLLIGESTEEIIACDLTKEQEKHEALLAAIATAEAQQDYVSRDLLEKQKDTNEEHIDWLETQQELIGKIGLPNYLQTAAQED
What is the function of this protein?
Iron-storage protein.
What are the official names of this protein?
Putative bacterioferritin B, BFR B.
What is the protein family that this protein belongs to?
Belongs to the bacterioferritin family.
Protein: MARE1_BOVIN
Sequence: MAVNVYSTSVTSDNLSRHDMLAWINESLQLNLTKIEQLCSGAAYCQFMDMLFPGSIALKKVKFQAKLEHEYIQNFKILQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYDGKEYDPVAARQGQETAMAPSLVAPALNKPKKPLSSSSAAPQRPITTHRTTATPKAGPGVVRKNPGVGNGDDEAAELMQQVNVLKLTVEDLEKERDFYFGKLRNIELICQENEGENNPVLQRIVDILYATDEGFVIPDEGGPQEEQEEY
What is the function of this protein?
Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton.  Promotes cytoplasmic microtubule nucleation and elongation.  Involved in mitotic spindle positioning by stabilizing microtubules and promoting dynamic connection between astral microtubules and the cortex during mitotic chromosome segregation.  Also acts as a regulator of minus-end microtubule organization: interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement.  Promotes elongation of CAMSAP2-decorated microtubule stretches on the minus-end of microtubules.  Acts as a regulator of autophagosome transport via interaction with CAMSAP2 (By similarity).  May play a role in cell migration (By similarity).
What are the official names of this protein?
Microtubule-associated protein RP/EB family member 1, APC-binding protein EB1, End-binding protein 1, EB1.
What is the protein family that this protein belongs to?
Belongs to the MAPRE family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Golgi apparatus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Associated with the microtubule growing distal tips. Recruitment to the Golgi apparatus requires the presence of PDE4DIP isoform 13/MMG8/SMYLE.
Protein: CTU2_BOVIN
Sequence: MCEMSEEYRESAPKGPPPPRLGTGDQKCVKCKEGLPVVVIRAGDAFCRDCFKALYVHKFRAMLGKSRLIFPGEKVLLAWSGGPSSSSMVWQVLEGLSRDSAKRLRFVPGVVYIDEGAACGQSPEDRARTLAEVKLALQTTGFPWHAVALEEVFSLPPSALRCSAQEAAGTEGAYKAAVDSFLQQQHALGTNGVERQSQHCAQDPQSPTGPPTTAQTQALSRLFDSVKTLTAKEELLQTLRTHLILHVARNHGYSKVMTGDSCTRLAIKLMTSLALGRGAFLAWDTGFSDERHGDVVVVRPMREHTLKEVAFYNRLFAVPSICTPALDTKAPEKASIHRLMEAFILRLQAQFPSTVSTVYRTSEKLVKAPRAGCAAGPRCLLCMCTLDVDTADSATAFGAQTSHLPQMQTPVTQARAAAGPCCCAGMGGAPGCCKREDPRAQVMEQLCYGCRVNMKDLPSLELLPPYILSEAQLRSQRATAEQEIREYLLGDSEDEAGTGES
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 2.
What is the protein family that this protein belongs to?
Belongs to the CTU2/NCS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FK127_ARATH
Sequence: MKKNKVPTELIFSLPNDLLVNILARVSRLDYPILSLVSKRFSSVLTLPELYQTRSLVGLTENCLYVCLLSSRADRIPSWFKLCRRPILASDTRKSSGYVLATIPIPHSPPLHRSSLVAVGSNIYNIGGSISQSQSSSVSILDCWSHTWLEGPSMQVEREYPSASLLDGKIYVTGGCRLTFHGCGDQTDNVVVDGKLHSCGGYKGVAYNPNDGRWDSLGSEMNLGLKWSSSCVIENVIYYYYHNENIKWYDTKVRSWRTLNGLKTLPRFARYANVRLADYGGKMALFWDKFTGCGNQNRMIWCAIIALERRNNEEIWGNVEWSDAVLPHQVPMAYVCEYVVAVNV
What are the official names of this protein?
Putative F-box/kelch-repeat protein At1g19930.
Protein: RLMG_SALEP
Sequence: MSHVDDGFRSLTLKRFPQTDDVNPLLAWEAADEYLLQQLDETEIRGPVLILNDTFGALSCALAEHSPYSIGDSYLSELGTRENLRHNGIAESSVTFLDSTADYPQAPGVVLIKVPKTLALLEQQLRALRKVVTAQTRIIAGAKARDIHTSTLELFEKVLGPTTTTLAWKKARLINCTFSHPQLADAPQTLSWKLEDTGWTIHNHANVFSRTGLDIGARFFMQHLPENLDGEIVDLGCGNGVIGLSLLAKNPQANVVFVDESPMAVDSSRLNVETNLPEAFERCEFMINNALSGVEPFRFNAVFCNPPFHQKHALTDNIAWEMFHHARRCLKINGELYIVANRHLDYFHKLKKIFGNCATIATNNKFVILKAVKQGHRR
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_NATTJ
Sequence: MPQQKLHVKSGDTVVVISGKDKGKRGKVLRTFPSEQKVLVEGVNMINKHTRATQENPQGGIVEQEGPVYADKVMVYCSKCQKPVRTGAKIDDKGNKSRICKKCGVEL
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: EX7S_AZOSB
Sequence: MPKPASSPTSFEAAVAELETIVQQMESGQLSLEDALARYQRGVGLLKFCQETLSGAEQRIRQLEGGELVELRIDTNADGSQECA
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIC_YERPS
Sequence: MSNNTTSLPAENSSHPRKGTPIRKKQREEAQQFINTLQGVTFPNSQRIYLQGSRPDIQVPMREIQLSPTQIGGSKNEPRYEDNEAIPVYDTSGPYGDPQAKLDVHNGLPKLRAAWVADRQDTEALASVSSGFTQQRLADEGLDHLRFEHLPRPRKAATGQCVTQLHYARQGKITPEMEFIALRENMGRERIRGEVLLQQHPGQAFGAHLPENITAEFVRQEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGVAENLTWEMFRDTLLEQAEQGVDYFTLHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICQICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPATARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQEQAAAQAQAATPTTAAQPIDITQPINMLQSGMEKMSAEFRSRGSELYHRPANLSAEANNEPT
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: DNAJ_ENTFA
Sequence: MATKRDYYEVLGLAKGASDDEIKKAYRKLSKKYHPDINKEADAEEKFKEVSEAYEVLSDPQKKAAYDQYGHAGTDPNYGGGAGGFGGFGGGGFSSSGFGGFEDIFDSFFGGGGGRSVDPNAPRQGADLQYTIQLKFEEAIFGVEKEIKYNREDTCATCGGNGAKPGTHPETCHKCHGSGTINVERQTPLGRMMSRQTCDVCHGTGKEIKEPCPTCHGTGHEKKAHTVKVNVPAGVEDGQQMRLANQGEAGTNGGPYGDLYVVFRVEDSDIFDRDGAEIYYDLPVSFVQAALGDEVTVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPRLRGGGNGDQHVKVKLITPKNLNEEQKDALRAFAKAGGQNVTEQQEEGFFDKMKDAFGGKKKK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.