PharMolix/UniProtQA huggingface dataset:
Protein: GUAA_ROSDO
Sequence: MSTSDHDRLLIIDFGSQVTQLIARRLRELNVYCEIHPFNLVDDAFLDAFGAKAVIFSGGPSSVFADGAPMPPASVFERGVPILGICYGQQVMMHCLGGKVERGHGTAEFGRAYVTPTAQKLDMLQGWFETDQDREQVWMSHGDHVSQIAPGFEVFGTSPNAPFAITADTTRHFYAVQFHPEVHHTPNGARLYENFVRLAGFKGDWTMGAYREEAIAKIREQVGSGRVICALSGGVDSSVAAVLIHEAIGDQLTCVYVDHGLMRKDESAQVVGMFREHYNLPLIHADESDLFLGKLEGVSDPETKRKIIGGLFIEVFEKYAKEIGGADFLAQGTLYPDVIESVSFSGGPSVTIKSHHNVGGLPERMNMQLVEPLRELFKDEVRALGHELGLPASFIGRHPFPGPGLAIRCPGEITREKLDILREADAVYIDQIRKHGLYDEIWQAFVAILPVRTVGVMGDGRTYDFACALRAVTSVDGMTADYYPFTHEFLGETATRIINEVPGINRVTYDITSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: MSCL_SHEB5
Sequence: MSLIKEFKAFASRGNVIDMAVGIIIGAAFGKIVSSFVADIIMPPIGIILGGVNFSDLSIVLQAAQGDAPSVVIAYGKFIQTIIDFTIIAFAIFMGVKAINRLKRKEEVAPKAPAAPTKDQELLSEIRDLLKAQQEK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YL247_MIMIV
Sequence: MTTYNLSKKSEIWKEIPIEGFEKYMVSNFGNVKNINTDKILSQSNRGGYFSVYLKPKDIDAQQKKIHRLVALTFVKNKDPENKKVVNHINGDKLDNRAENLEWVTASENVQHAVDNNLITMTKRAVIQCNLKTGKKIKEFESVTDASNETGISTGHICDAANGKWKQAGGYAWKYSKKDSAKIDIDMSKFKQLVDFPNYLINNEGQVYSLARKRFMKPIHRGDSGMNISLSEGDKQKTMLVHKLVASYFLKKNNDDHNHVRHKDGNRQNNNVSNLEWCYLGGMDKHKPESHFSHDYYDEKTAIPLTERKKAVKTIKSSGSKTSKSIGSKTNKSAGSKTASKLGSKTAIKSGSKTTSKISTKSGSKTAIKSGSKTASKISTKSGSKTSKTSKSIKYYEV
What are the official names of this protein?
Uncharacterized HNH endonuclease L247.
Protein: RF1_METEP
Sequence: MTPIPSDRLDAILARHDIVTAQLADGSADAGSIVQLSRELSELDGVVAAIHHYRLAEANLAGIRAMIDEPGGDPEMRALAAEEKPEAEEALEQAHRALQLILLPKDAADEKSAILEIRAGTGGDEAALFAGDLFRMYARYAESKGWRVEVISESEGTAGGYREVVAEVKGRSVFSRLKFESGAHRVQRVPDTETQGRIHTSAATVAVLPEAEEVDIVVNEADLKIDTMRAQGAGGQHVNKTESAIRITHIPTGVVVFVQEERSQHKNRARAMSLLRSKLFDAERTAKDSARAADRKAQVGSGDRSERIRTYNFPQGRVTDHRINLTLYKLEEVMAGQALDEVIDALVTEHQAELLAAEGMA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED16_ASPCL
Sequence: MPLIMEDGINVDDLFGEPGSLELGLSPPSNAPIKGLPQRLDEMRLVGCCQKIAWSRLGCVAYITPDGMRVNVRHLQCRPSDGKWVLSEDTPLLPVTEAHGGHPLVHLCWNETGAELAVADSSGRVSIYSISIALNSIAGHRQATSDPDDDGAQIVGMMWLNVNRVVHAFHQAAKVQGRWAYSPFRRRPIGPFHPVNKAGLVCVTRSGTIRLLYQNPDSRWAEISTELKNTGYSDRLLTHAALVSTQGGVLVATHSACQKLCLYRVQIAWNPTQYDPGQQKPPAPWPVPSFRFLHCKVESLCDVIGTNRNPGDNQGLPSFTNSVYGLTRLDIILPALDNPAGSTSTPWIVAVYSSPLHATPDHPQQQSPASVIVRWQLDTGAVTLHPKFDEVGSKKSSAQMKPKLELRRLEDIYSDRYAISIDQIEYGNVLAITYEDGSIVFHDPKTMAVFNGVDDTNTVTSLAQAGFHYPPEASGLHMAFSPNACAAVMLDAEGQTQLRLTEHTYGAEGGLHDENKYSAAIAALTLAFCRGCGSDVNIDDVILILVRQLSSEAQINFINEVYRALSVNCNFTMEQDKLMNHIYIPRCLSLQAALGFKDKYTPRSSPSAIPWAILQLRHASVLYAFFFQYNKGAPTESHDPDVLRMVLGNTKWALEFSFYVSNELFDLADEFESMASDQEAFTQKLKSTTSLPLIILLSSMSRAFLRFICRGLRGIHAGYATAAPLTGDARVYYAEIYQTLENSPVRIDAYEKFLAGVDSAVRHAYHSAGFGDAERPGPEKELLVNARVPPVLVSAVATILRQTVPALKSEIDRITIYMGNYSWLGLAHDRRTEMYRRTRDVDIIKKIPLRSLGPYTEVDAAPSGKTNAQGPPQQPQPQQQRRRRCVRCCEISGDTHPPRSLLSFRMIAKLGLLRSCVCGGMWTLVEPEVSAPAADPPVSQATGRTPALMAIGLAGSS
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 16, Mediator complex subunit 16.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 16 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNMC_CAMC1
Sequence: MKNANLSFKGQIPFNEEFDDIYFNTEKPWLESEFVFTSALDEIWQSKDSFIVAETGFGAGLNFFTLCKKFKNSSKKLHFVSIEKSPIKKEDLLKIYENLGIFKAYVKKLVSLYPPLISGIHRINFAPNITLDLCYGEADQILPELDFAADIWFLDGFAPSKNGSIWSEDVFKQIARLSRVGTIARTYSCAKIVKVGLKNAGFLLSLKEGYARKRQMSSAVLEKKDENLKDAWFARCEPVGSVNGKTALVIGTGVAGLATAGELAKNGFKVVIAEAKSEVATNGSGNHCGALMPLVTKPGVNLGRMHINAFLQAVRFYKANLPKSLIKFNGCIDYAFDDELVKRYSSWQDQSAEDLFKFNESLKPYPGIFIKEAAYARPREICKFLSSNFEILFNHEYESRAHLQNGKISVKFKNKKSLETDILVFCTGSKSSEIFKDYDMQISSVRGQVTHLKPVLKNELPLSAKGYICPAVKGVQVIGATYARNEICDTPKDEDNAKNLSDVSEFFDTTKAAIIGSRVGYRSYSGDRFPIIGALHDEEFYKQNYKGLFWSKNKDNNPKASYEKNVFVNFAHGSRGLGTAILGANLITDLVLARPLCIERSLFFELHPARFLIRKLKKGLK
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORF58_HHV8P
Sequence: MCRLDSERALSLFSYLSGTLAATPFLWCFIFKALYSFTLFTTEITAVFFWSLPVTHLALICMCLCPAAQKQLDRRLEWICASAVFAAVVCAAFSGFTFSRVPFIPGLCVLNCLLLLPYPLATATAVYQAPPIVHRYYELGFCGAFMVYYLLLFKKVFVSGVFWLPFIVFLVGGLLAFRHLEQHVYIRAGMQRRRAIFIMPGKYITYSVFQAWAYCRREVVVFVTLLLATLISTASIGLLTPVLIGLDKYMTLFYVGLLSCVGVSVASRRALFVLLPLAAVLLTLVHILGSGPDMLLVRSCLCCLFLVSMLAAMGVEIQLIRRKLHRALNAPQMVLALCTVGNLCISCLLSVINKVVG
What is the function of this protein?
Participates in rearrangement of cellular actin to increase intercellular contacts and thereby promotes virus cell-to-cell spreadin$g.
What are the official names of this protein?
Protein ORF58.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae BMRF2 family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host cell membrane.
Protein: H2AV_RABIT
Sequence: MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGAIPHIHKSLIGKKGQQKTA
What is the function of this protein?
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.  May be involved in the formation of constitutive heterochromatin.  May be required for chromosome segregation during cell division (By similarity).
What are the official names of this protein?
Histone H2A.V, H2A.F/Z.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RL22_BACC0
Sequence: MQAKAVARTVRIAPRKVRLVVDLIRGKQVGEAIAILNHTPKTASPVVEKVLKSAIANAEHNYEMDINSLVVEKVFVDEGPTLKRFRPRAMGRASQINKRTSHITVVVSEKKEG
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RECF_BACSU
Sequence: MYIQNLELTSYRNYDHAELQFENKVNVIIGENAQGKTNLMEAIYVLSMAKSHRTSNDKELIRWDKDYAKIEGRVMKQNGAIPMQLVISKKGKKGKVNHIEQQKLSQYVGALNTIMFAPEDLNLVKGSPQVRRRFLDMEIGQVSPVYLHDLSLYQKILSQRNHFLKQLQTRKQTDRTMLDVLTDQLVEVAAKVVVKRLQFTAQLEKWAQPIHAGISRGLEELTLKYHTALDVSDPLDLSKIGDSYQEAFSKLREKEIERGVTLSGPHRDDVLFYVNGRDVQTYGSQGQQRTTALSLKLAEIDLIHEEIGEYPILLLDDVLSELDDYRQSHLLHTIQGRVQTFVTTTSVDGIDHETLRQAGMFRVQNGALVK
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.  Is recruited to repair centers, foci that are the site of double-strand DNA break(s) after RecN and RecO; recruitment may depend on RecO.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Cytoplasmically located in untreated cells. Recruited to foci following treatment with DNA damaging agents; these foci are presumably the breaks themselves. They are almost always located within nucleoids.
Protein: BSHC_BACAA
Sequence: MEIKEISVPQQGVVADYMNGKKEIQSCFDYMLTEDAFKQRVQDLREREFFRQDLVTHLLEYNTKLQAGEATIQNVKALGDENTYVVIAGQQAGLLTGPLYTIHKIISVLQLAKEKEESLGVKVVPVFWIAGEDHDMDEINHTFVTKNKKIKKTIFHDRNPKKASASESELSLEDCRKWIEEIFKTYPETNFTKDVLQFIDDSLRKSNTYVDFFGHLIMKMFVNSGLILVDSHHPELRKLEVPFFKQIVSKYKEVQEGLHNQQRVIKELGYKPIIETKSNAVHIFMEIDNERVLLEDNQGKFVGKDGTYSFSYKELIEEMERSPERFSNNVVTRPLMQEYVFPTLAFIGGPGELAYWSELQQVFHTIGFRMPPVVPRITITYIERDIATDLHDLQLQESDPFFNNVDKLRENWLSNQIEEPIDERFVEAKKEIIDIHKSLQQFVKKIDPGLSAFAGKNEFKINEQIELLERMLKRNVEKKHEVELNKFRRIQFALRPLGAPQERVWNVCYYLNQFGLDFVDRVMEKPFSWNGKHHVIKL
What is the function of this protein?
Involved in bacillithiol (BSH) biosynthesis.  May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.
What are the official names of this protein?
Putative cysteine ligase BshC.
What is the protein family that this protein belongs to?
Belongs to the BshC family.
Protein: PHEA_MYCS2
Sequence: MPRIAYLGPEGTFTEAALLQMVAKGMVPGPAEDAGGFTPVRTDSTPGALSAVREGRADYACVPIENSIDGTVLPTLDSLAAGSPLQIYAELTLDVAFTIVVRPGHDGPVRTVAAFPVAAAQVRHWLAANLRDAEVVPAHSNAAAAHDVAEGRADAGVSTRLAAERCGLDIMAADVVDEPNARTRFVLVGLPGTPPPATGADRTAVVLRLVNEPGALVSAMTEFSIRDIDLTRIESRPTRTELGTYMFFLDCAGHIDDDPVAEALKALHRRCVDVRYLGSWPTESAAGAPPPRLDEATTWLEGLRAGSGGA
What are the official names of this protein?
Prephenate dehydratase, PDT.
Protein: CING_XENTR
Sequence: MERDLYGDMADQPIPVGQGVQIRFINDLKENGKPRGKRSKQDSYGVAVRVQGIDGQPFVVLNSGDKAKSSYDYDRHYSERSSTLDTAYSQSSRESAWSRGSQKKTDNGEYPSLGYRSATSQQSTSASNKTNKNGLSTSSFSNQSSEDIDTKPLSSVDSLITKFDVKGQVRGRTARRSQALKDERKRSQSLDGRKNYQDTADSREISLQQQNEVPARRETVSSANRSFARQSLEREDINKTRLTKEWLDQGGEEPVIVKQQRSVQSEFQLKSTPDLLRDQQADGSDPTREMIFSILRDGSTENENNLRKKTSILLEKFPSLQAQPGEDTRSLGSQKKELERKVAELQRQLDDEMKQRMKLESSQGRPKAGMQRLEIQLEESKEECSRLKDLYDKKKNELNAVSQELMEVRMGKEQVETKLRAMEDKLMDSKEELSHLRAKGGTSPDKLALMKELEEVQDELDEVLQIRQKQEELLRQKDRELTALKGALKDEVANHDKDLDRVREQYQNDVQQLRKNMENVSQDQLSLETERQKINQVVRNLQRELEESSDEINQWKEMFQKNKEELRSTKQELLQMKMEKEESEDELKETKDRFSLLQSELEQAKKGSVDPGELASVRKELQRVQDQLKQLSVDKQKVEENLHQRERELSALKGALKEEVAGRGRETERLREQLQSEVVQFKKDNENLGRESQRIQDQLKQVLLEKQRHEEAVHQRERELSALKGALKDEVSGRDREAERLRAQFEQDAMQTKRSYEELVKINKRLESEKVDLERVRQVIENNLQESREENDDLRRKILGLEAQLKETNTFCDDLQRAESRLKDKITKLETERKRMEDTLGEAADQEQELAFVKRDLGNKLEEAQRSLKRLSLEYEELQECYQEEMKQKDHLKKTKNELEEQKRLLDKSMDKLTRELDNMSNESRGSLQVLQSQLEEFREKSRREIGEAQKQAKEKTAEAERHQFNSSRMQEEVQKLKLALQELQVEKETVELDKQMVTQRLQNLEQDTESKKRVQDDRSRQVKVLEDKLKRMEAELDEEKNTVELLSDRINRSREQMEQQRAELMQERARGQDLECDKISLERQNKDLKGRLANMEGQQKPSVNVSHLEAKLQDIQERLQSEEREKATLLSTNRKLERKLKELNIQLEDERLHVNDQKDQLNLRVKALKRQVDEAEEEIERLEGLRKKAVREMEEQQELNEQLQTRLKTMEKESKRKPIRPAHNDDDDLSSDGEYGGSYDPSSITSLLTESNLQTSSC
What is the function of this protein?
Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier, possibly by linking ZO proteins to the actomyosin cytoskeleton.
What are the official names of this protein?
Cingulin.
What is the protein family that this protein belongs to?
Belongs to the cingulin family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Note=Localizes to the apical junction complex composed of tight and adherens junctions.
Protein: CHLL_MESVI
Sequence: MKIAVYGKGGIGKSTTSCNISIALARRGKKVLQIGCDPKHDSTFTLTGFLIPTIIDTLQSKDYHYEDVWPEDVIYKGYGGVDCVEAGGPPAGAGCGGYVVGETVKLLKELNAFYEYDVILFDVLGDVVCGGFAAPLNYADYCIIITDNGFDALFAANRIAASVREKARTHPLRLAGLVGNRTSKRDLIDKYVEACPMPVLEVLPLIEDIRVSRVKGKTLFEMVETEKSLNYVCEFYLNIADQLLARPEGVVPNEVPDRELFSLLSDFYLNPVNTSNESTNSSIEANQEVESSFLII
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RNT_ACTP2
Sequence: MTEQVTDYNFLKNRFRGYLPVIIDVETAGLNAQTDALLELAAITVKMDENGYLVPDQKCHFHIQPFEGANINPDSLKFNGIDIDNPLRGAVPENIAIPEMFKMVRRAMKEQGCQRAVIVAHNATFDQAFVQAAVKRINAKRDPFHPFAMFDTATLAGFMYGQTVLVKACQMAKIPFDGKQAHSALYDTEKTTELFCAMVNRLKDLGGFPLVSDSESNV
What is the function of this protein?
Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang.  Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A).  Also appears to be involved in tRNA biosynthesis.
What are the official names of this protein?
Ribonuclease T, Exoribonuclease T, RNase T.
What is the protein family that this protein belongs to?
Belongs to the RNase T family.
Protein: SBDS_XENLA
Sequence: MSIFTPTNQIRLTNVAVVRMKKGGKRFEIACYKNKVMSWRSGAEKDLDEVLQTHSVFMNVSKGQGAKKEDLLKAFGTEDQTEICKQILSKGELQVSEKERSTQLEQMFRDIATIVADKCVNPETKRPYTVNLIERAMKDIHYSVKATKSTKQQALDVIKQLKETMQIERAHMRLRFIVPAKDGKKLKEKLKPLIKHIESENFDQELEIVCLIDPGCFREIDELIRCETKGKGTLEVLSLKDVEEGDEKFE
What is the function of this protein?
Required for the assembly of mature ribosomes and ribosome biogenesis.  Together with EFL1, triggers the GTP-dependent release of eif6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating eif6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export.  Required for normal levels of protein synthesis.  May play a role in cellular stress resistance.  May play a role in cellular response to DNA damage.  May play a role in cell proliferation (By similarity).
What are the official names of this protein?
Ribosome maturation protein SBDS, Shwachman-Bodian-Diamond syndrome protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SDO1/SBDS family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, spindle. Note=Primarily detected in the cytoplasm, and at low levels in nucleus and nucleolus. Detected at the mitotic spindle. Colocalizes with the microtubule organizing center during interphase (By similarity).
Protein: NU5M_EMEND
Sequence: MYLTLIILPLLGSIVSGFFGRKVGVTGAHLITCVSVVTTTILAILAFLEVGFNNIPVTINIARWLDVESLYVLWIFRFDSLTVSMFITVLIVSSLVHIYSISYMSHDPHNQRFFSYLSLFTFMMIILVTGNNYLIMFVGWEVVGVCSYLLVNFWFTRIAANQSSLSALLTNRVGDTLLTVGMFAILWSFGNIDYSTVFALAPYYNENIITLIGICLLIGATAKSSQVGLHIWLPQAMEGPTPVSALIHAATMVTAGVYLLMRSSPLIEYSSTVLVLCLWLGAITTVFSSLIGLFQQILKKLFAYSTMQLGMMVIAVGLSSYNLALFHLVNHAFYKALLFLGAGSVIHAVADNQDFRKYGGLREFLPLTYYVMLIASLSLVAVPFMTGFYSKDYILESAYGQYYLSSTIVYFVATIGAMFTTLYSAKVLYLTFLTNPNGPLVNYKHAHEGDLFMTTPLIILAIIYIHSGYITKDIFIGLGTGFSLINSYYSPSHEIMLDTEFAVPTLFKLLPFILSISLSVISVLLSEFLPKLLINFKFSRLGYNIFSFFNQRFYIELFYNKYIVEGVLKLGGQTSKSLDKGSVELLGPYGLEKALLSLSNSIGKLSTSVVTTYALYILIGLIFYISLLYFSYNDNNLFILVIFTLFVLLNNNIINKF
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CLS_LISMC
Sequence: MGLLAYLLVILLILNVFFAAVTVFLERRDTSATWAWLLVLTFVPIFGFIIYLIFGRKLSGKKIFDWKGQEKIGIQESTANQIEMIRQKEFPFSDPNVKKHRDLIYLLLVNDGAILTQDNEVELFVDGHEKFDALIADIEKAKDHIHLIYYIFHSDELGNRLMRVLERKAAEGLNVKIIYDAMGSRTTKKSFFRTFQKNGGLVRPFFPSKLPLINFRLNYRNHRKLAIIDGDVGYIGGFNIGDEYLGASKKFGYWRDTHLRVHGKAVYAMQTRFIMDWNSASSTHKIDYKARYFPTFHGKGHTSMQIVSSGPDSEWQQIKNGYIKMINAAKKTIYLQSPYFIPDASLLEAIKIAALSGVDVRVMIPNKPDHAFVYRATTNYAGELMETGAKIFIYDNGFIHAKTLVVDGEIASVGTANMDFRSFRLNFEVNAFIYEKQMVQKLEDAFLEDILKSYQLTPELYAKRSLWIKFKEAVSRLLSPIL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS16_CLOAB
Sequence: MVKIRLKRMGAKKAPFYRIVVADSRSPRDGKFIEELGYYNPTTEPVTFKVDADKVNAWMKNGAQPSETVKKLLDKSGVTTK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: PPE63_MYCTU
Sequence: MADFLTLSPEVNSARMYAGGGPGSLSAAAAAWDELAAELWLAAASFESVCSGLADRWWQGPSSRMMAAQAARHTGWLAAAATQAEGAASQAQTMALAYEAAFAATVHPALVAANRALVAWLAGSNVFGQNTPAIAAAEAIYEQMWAQDVVAMLNYHAVASAVGARLRPWQQLLHELPRRLGGEHSDSTNTELANPSSTTTRITVPGASPVHAATLLPFIGRLLAARYAELNTAIGTNWFPGTTPEVVSYPATIGVLSGSLGAVDANQSIAIGQQMLHNEILAATASGQPVTVAGLSMGSMVIDRELAYLAIDPNAPPSSALTFVELAGPERGLAQTYLPVGTTIPIAGYTVGNAPESQYNTSVVYSQYDIWADPPDRPWNLLAGANALMGAAYFHDLTAYAAPQQGIEIAAVTSSLGGTTTTYMIPSPTLPLLLPLKQIGVPDWIVGGLNNVLKPLVDAGYSQYAPTAGPYFSHGNLVW
What are the official names of this protein?
Uncharacterized PPE family protein PPE63.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
Protein: ARI2_DROME
Sequence: MDSDIEMDMESDNDGEYDDDYDYYNTGEDCDVERLDPKRADPEYFEYECLTVEDIEKLLNERVEKLNTILQITPSLAKVLLLEHQWNNVAVVEKYRQDANALLVTARIKPPSVAVTDTASTSAAAASAQLLRLGSSGYKTTASATPQYRSQMCPVCASSQLGDKFYSLACGHSFCKDCWTIYFETQIFQGISTQIGCMAQMCNVRVPEDLVLTLVTRPVMRDKYQQFAFKDYVKSHPELRFCPGPNCQIIVQSSEISAKRAICKACHTGFCFRCGMDYHAPTDCQVIKKWLTKCADDSETANYISAHTKDCPKCHICIEKNGGCNHMQCFNCKHDFCWMCLGDWKTHGSEYYECSRYKDNPNIANESVHVQAREALKKYLHYYERWENHSKSLKLEQQTIDRLRQRINSKVMNGSGTWIDWQYLFNAAALLAKCRYTLQYTYPYAYYMEAGSRKNLFEYQQAQLEAEIENLSWKIERAETTDLGDLENQMDIAEKRRTTLLKDFFPVDA
What is the function of this protein?
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
What are the official names of this protein?
Potential E3 ubiquitin-protein ligase ariadne-2, Protein ariadne-2, RING-type E3 ubiquitin transferase ariadne-2.
What is the protein family that this protein belongs to?
Belongs to the RBR family. Ariadne subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PGK_LEPIN
Sequence: MELPRLENVDLSGKRVFLRVDFNVPVENGKVTDKTRIEKTLPTIELLIKKGARIIIASHLGRPKGQVNPEFSLAPVVETFQSLVKSKVYFSKTVIGEDAIKLSKELKNGEILVIENVRFHKEEEENDPGFSKKLSALADIYVNDAFGAAHRAHSSTEGIARLLPAYAGLLMHKEILELSALLHKPARPFVAIIGGSKVSTKIKVLTNLFDKVNHLLIGGGMAYTFLKSRAIPIGNSLVEKEFEVQAFQLIEKAGVAGIDLQLPVDHIIGDQFNEKAKTKSVDKMGILDGWMGMDIGSKTVSNYEKIIKNAGTIFWNGPMGVFEMDKFASGTMAIAKAVAKSKAKTVVGGGDSIAAINKAGVADKITHISTGGGASLEFMEGRKLPGVEALKKKTSE
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYH13_HUMAN
Sequence: MSSDAEMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFVADNKEMYVKGMIQTRENDKVIVKTLDDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPELIDLLLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKLLSFLFSNYAGAETGDSGGSKKGGKKKGSSFQTVSAVFRENLNKLMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQKMEE
What is the function of this protein?
Fast twitching myosin mediating the high-velocity and low-tension contractions of specific striated muscles.
What are the official names of this protein?
Myosin-13, Myosin heavy chain 13, Myosin heavy chain, skeletal muscle, extraocular, MyHC-EO, Myosin heavy chain, skeletal muscle, laryngeal, MyHC-IIL, Superfast myosin.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.