PharMolix/UniProtQA huggingface dataset:
Protein: SODC_CAMDR
Sequence: MALKAVCVLKGDGQVQGTIHFEQKENGPVMVSGSISGLAEGDHGFHVHQFGDNTQGCTSAGPHFNPLSKKHGGPKDQERHVGDLGNVTAGKDGVAIVSIEDPVISLSGDHSIIGRTMVVHEKPDDLGKGGNEESTKTGNAGSRLACGVIGIAQ
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: P7_ISAV8
Sequence: MREANPKPRELIRHALKKKKRPEVVYAMGVLLTLGGESGLTVEFPVPEGKTVKVKTLNQLVNGMISRATMTLYCVMKDPPSGGMATLMRDHIRNWLKEESGCQDADGGEEKWAMVYGMISPDMAEEKTMLKELKTMLHSRMQMYALGASSKALENLEKAIVAAVHRLPASCSTEKMVLLGYLK
What is the function of this protein?
May play a role in inhibition of the host immune system by counteracting the type I interferon response.
What are the official names of this protein?
Protein P7, P7.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RPOZ_NITMU
Sequence: MARITVDDCLKKIPNRFDMTLVATIRARQLSVGGSPMVEPARDKPTVIALREISQGLVGTDILTTGPI
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: KTNB_ASPNC
Sequence: MTYPEEIDEYSLIQNGLKSLNEAAQRCQQTKHSSQDSSIEGCSARQSARDELVLEALKFLQIAQGPIDAAATCYERTAHLASVRALLEMGVFEALPTGRVSRRTEELARELNVDESLLARLLRNSSLYGPFEETGPGQYRHTPFSEAYLRPEIRGMFRFAMDDHMPAHLKLHEFLQRNGWQEPSSTTDNPYTYAHKTNGKSMFDNLSEKPERMKAFNNGMTVQAMTPLWMIDLFPWRSLAQLKPTAGQVLAVDIGGGKGKAISRIRSFCNGLPGRYILQDQEHVVKSVEGSLDPSIERMAYNFFTEQPIRGAVTYLIRRCLHNWPQDSVVCILQNIAAAMEPGKSRLLIEEIVVPAEKAGVEEGWMDMIMMSLGAKQRTLKEWEMVLGLAGLEVKKVYQIPGNCHGLIEAWLK
What is the function of this protein?
Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of the bicoumarin kotanin (PubMed:22945023, PubMed:26389790).  The non-reducing polyketide synthase ktnS first catalyzes the formation of the pentaketidic 4,7-dihydroxy-5-methylcoumarin from acetyl coenzyme A and 4 malonyl coenzyme A molecules (PubMed:17315249, PubMed:22945023).  Further O-methylation by ktnB leads to the formation of 7-demethylsiderin (PubMed:17315249, PubMed:22945023, PubMed:26389790).  Then, an oxidative phenol coupling catalyzed by the cytochrome P450 monooxygenase ktnC forms the 8,8'-dimer P-orlandin via dimerization the monomeric precursor, 7-demethylsiderin (PubMed:26389790).  P-orlandin is subsequently O-methylated in a stepwise fashion to demethylkotanin and kotanin (PubMed:22945023).
What are the official names of this protein?
O-methyltransferase kntB, Kotanin biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.
Protein: MACB_CHLTE
Sequence: MIEIVNVTKTYRIGESSVKALDGVSLTIGQGEFVAIMGASGSGKSTLMHILGLLDVPDTGQYRLMGKEVSRMSDDELAGIRNNVAGFVFQQFHLLSRMSTIDNVVLPCIYSGQRGDFRKDALKRLEMVGLAQRSDHRPNQMSGGEQQRVAIARALIRDPMLIFADEPTGNLDTKNSHEIMRILTDLHRQGKTIIMVTHETDIAEFADRVITMKDGVVVDDRKKQDARLNPQMPQGGMEAAHSALFQPSRLLGFVVQAFQSIASNKIRTFLSVLGILVGVASVIAMMALGTGAKASMEEQLKSMGSNLLSVRGGSAKIGGASQGFGTVTRFTEKDAAAIQAIPNLIDHVSGDVTGSGQLVYLDKNWSTSVEGVDYDYGEMRAAIPTVGRWFTREEIQERAKVAILGTTVAMQLFGDADPVDKIIKINRINFRVIGVAPAKGFAGPRDQDDVVYIPVSTAMYRVLGKLYLDGIYVEVSSAENIAPATQAIDALIRKRHKLAADDQDSFNIRDMTQFQQMLSATTQTMSMLLGSIAAISLVVGGIGIMNIMLVSVTERTREIGLRKAIGARKGDIMLQFLIESVGMTLSGGIIGIVVGVGVSVMLSAFAGWAVKTSMFSVVLATGFSVLIGLFFGLWPARKAAALKPVEALRYE
What is the function of this protein?
Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYR_BACC1
Sequence: MNSLEQVKGLIKEEIQAAVLKAELATEEQIPNVVLESPKDKTNGDFSTNMAMQLARVAKKAPRMIAEELVANFDKAKASIEKIEIAGPGFINFYMDNSYLTDLIPTIVNAGEAYGETSTGKGEKVQVEFVSANPTGDLHLGHARGAAVGDTLCNLLAKAGYDVSREYYINDAGNQIHNLALSVEARYMQALGLEKEMPEDGYHGADIIAIGKRLAEEFGDRYAKADEKESYEFYREYGLKYELAKLQKDLESFRVKFDVWFSETSLYKNGKIDQALAVLKERDEIFEEDGATWFRSMTYGDDKNRVLIKNDGSYTYLTPDIAYHRDKLERGFDKLINIWGADHHGYIPRMKAAIQALGYDKETLEVEIIQMVQLYQNGEKMKMSKRTGKAVTLRELMEEVGVDAMRYFFAMRSGDSHLDFDMDLAVSKSNENPVYYAQYAHARVCSILRQGEELGLATGGDVNYKLVTSEKEVELLKKLGEFPAVVADAAQKRLPHRITNYAFELAAALHSFYNAEKVLNQDNLELSKARYELMKAVRTTLQNALAIVGVSAPEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_EDWI9
Sequence: MTATAQQLEFLKQNIKTIPDYPKPGILFRDVTSLLEKPDAYALSIELLAARYRAAGITKVVGTEARGFLFGAPVALALGVGFVPVRKPGKLPRATLAESYALEYGTDTLEIHQDAIDANDRVLMVDDLLATGGTIEATTRLIRRLGGVVHDAAFIIDLPALGGEARLEAMNINCYSLVSFDGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAO1B_XENLA
Sequence: MESISQLQPPMGVNFLNIAPTYIPNTKVECHYTTPFGMKRSTRDWIGIFKVDTSSIRDYETFVWAVPPESSGERSVSHCSVQFQAYYLPRPGEQQYHFRYVDQYGSVRGCSDAFVFGEPRPMEELVTLEDEDSCMDMLLVVPKATFLQNQLEMAQQERNDLMRARLALEEEVILKEKRINHLEATLETSEKSCFSLKEQCQDLVMREQLAIEEQSLLSCQEAELRERILQLQGEIKIMNKKMQEKDRELEGTVAIKLSLENKKVVLKQHLAETTVEIKRYQLQVDSLREKLRSTQDMLSASQQKALLMGEELAAISSIRDRTISDLHKSRLETADLAIKVSDLSVKYKEGMGQWWQEKTALNHSMEAKRDQIVNLKAEKLSLENSLQAERSQRQALQCKLNQETDARQVQLSENRRQLSELKSALKVAQMEKQQLREERQGILQYARSLEERLDKLADELWKEDKMLMEEITDLNPPTLPVDHSDSDDESPGDERVSQQLEACSLDEQDLTINLPGFPCELYKVVINQPAPIACQLQPLPEDNSDSW
What is the function of this protein?
May function as a coactivator for aryl hydrocarbon and nuclear receptors.
What are the official names of this protein?
Calcium-binding and coiled-coil domain-containing protein 1-B.
What is the protein family that this protein belongs to?
Belongs to the CALCOCO family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Detected in the cytoplasm at stages I- II. Detected in the nucleus and the cytoplasm, except for the germ plasm, of almost all cells in cleaving embryos (By similarity).
Protein: HUTI_METNO
Sequence: MQCDRLWHNARLATLAESRPGLGLVEDGVIAARDGRILHAGPTAEAPSFAARETIDCEGRWITPGLIDCHTHLVFGGDRAQEFEARLAGASYEEIARAGGGIVSTVRATRAASEDDLVAGALRRLDALIAEGVTTVEVKSGYGLSLAAERASLRAARRLGAERDVTVTTTFLGAHALPPEESDRDRFIDRICAEMLPAIAQEGLADAVDAFCEGIAFSPVETARVFEAARDAGLPVKLHADQLSNLGGAALAARFGALSADHLEYTDEAGAAAMAQAGTVAVLLPGAFYFIRETKVPPVDLFRRHGTRIALATDCNPGTSPLTSLLLVLNMGATLFRLTVEECLAGVTREAARALGRLHDLGTLEAGKWCDLAIWDIERPAELVYRMGFNPLHARIRRGR
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCXD_CENLI
Sequence: KEGYLVDYHTGCKYTCAKLGDNDYCVRECRLRYYQSAHGYCYAFACWCTHLYEQAVVWPLPNKRCKGK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing (By similarity).  Inhibits sodium channels Nav1. 4/SCN4A, Nav1. 5/SCN5A and Nav1. 6/SCN8A (PubMed:27871874).  Also has a weak inhibitory effect on Nav1. 2/SCN2A (PubMed:27871874).  Is lethal to mice (PubMed:27871874).
What are the official names of this protein?
Beta-toxin Cl13, CliNaTxBet37.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SCOB_HELPJ
Sequence: MREAIIKRAAKELKEGMYVNLGIGLPTLVANEVSGMNIVFQSENGLLGIGAYPLEGGVDADLINAGKETITVVPGASFFNSADSFAMIRGGHIDLAILGGMEVSQNGDLANWMIPKKLIKGMGGAMDLVHGAKKVIVIMEHCNKYGESKVKKECSLPLTGKGVVHQLITDLAVFEFSNNAMELVELQEGVSLDQVKEKTEAEFEVHL
What are the official names of this protein?
Succinyl-CoA:3-ketoacid coenzyme A transferase subunit B, OXCT B, Succinyl-CoA:3-oxoacid CoA-transferase.
What is the protein family that this protein belongs to?
Belongs to the 3-oxoacid CoA-transferase subunit B family.
Protein: CCMA_RHOPS
Sequence: MWLSGRGLRCVRGGREVFDGLGFEAAGGEALALVGHNGAGKTSLLRLIAGLLAPAAGTITFDGGEPDTPVAEQAHYLGHRDALKPSLSVTENLAFWREFLGGEPTDLPAAIEAVGLAHAAELPAAYLSAGQRRRLSIARLLVVRRPIWLLDEPTSALDVRGQEAFGRLMSDHLAGGGLIIAATHSPLGIAAREMRIGAAA
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TXM46_CONAO
Sequence: CCRLACGLGCHPCC
What are the official names of this protein?
Conotoxin Ar1446, Conotoxin Ar1430.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATG5_DICDI
Sequence: MSSFDEDIKRSIWEGKIPIVFTLSPDDLTSHLSPSPYTLMAPRNSYFPLITSLVKDYFSSSTLVLLDEMWLEYRGIPLKWHLPIGVLYDTIVGNNNCNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIIMEQPYWNIVVHFQSYPDRILLRCPNIESVRTYYKNVLKEANFIKQGDITKINNLNINQSNDLWDGLKSHDYDKFWSVNKKLIPNSNKEYKNIPIRLIINYKPPIQELIPVFDENLVELTLENLFSRIPYESFSNFLNYNNNNNNNNINNNSPPLSPNSNNNNNNNNVDNSIENSLNQTNVESAEPEFSNLLQYIKATNAEYKIQGIQPSLKSSAVWLYEHFGHPDNFLYIVLIDPSQNNNNNNNNSNNY
What is the function of this protein?
Involved in autophagic vesicle formation.  Conjugation with atg12, through a ubiquitin-like conjugating system involving atg7 as an E1-like activating enzyme and atg10 as an E2-like conjugating enzyme, is essential for its function.  The atg12-atg5 conjugate acts as an E3-like enzyme which is required for lipidation of atg8 and its association to the vesicle membranes (By similarity).
What are the official names of this protein?
Autophagy protein 5.
What is the protein family that this protein belongs to?
Belongs to the ATG5 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: METH_VIBVU
Sequence: MGSQIRAQIEAQLKQRILLIDGGMGTMIQGYKLQEQDYRGERFADWHSDLKGNNDLLVLTQPQLIKEIHHAYLEAGADILETNTFNATTIAMADYDMESLSEEINFAAARLAREAADEWTAQNPAKPRYVAGVLGPTNRTCSISPDVNDPGYRNVSFDELVEAYSESTRALIRGGSDLILIETIFDTLNAKACAFAVDSVFEELGFALPVMISGTITDASGRTLSGQTTEAFYNSLRHVRPISFGLNCALGPDELRPYVEELSRISETFVSTHPNAGLPNAFGEYDLSPEEMAEHVKEWAQSGFLNLIGGCCGTTPEHIRHMAMAVEGVSPRVLPEIPVACRLSGLEPLTIAKDTLFVNVGERTNVTGSARFKRLIKEELYDEALDVAREQVENGAQIIDINMDEGMLDAEACMVRFLNLCASEPEISKVPIMVDSSKWEVIEAGLKCIQGKGIVNSISLKEGKEKFVEQAKLIRRYGAAVIVMAFDEVGQADTRERKLEICTKAYRILVDEVGFPPEDVIFDPNIFAVATGIDEHNNYAVDFIEAVADIKRDLPHAMISGGVSNVSFSFRGNNYVREAIHAVFLYHCFKNGMDMGIVNAGQLEIYDNVPEKLREAVEDVVLNRRDDATERLLEIAEEYRENAVGKQEDASALEWRTWSVEKRLEHALVKGITEFIVEDTEEARLNASKPLEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAHLEPFINASKQAGSSNGKILLATVKGDVHDIGKNIVGVVLQCNNYEIIDLGVMVPCEQILKVAKEQQVDIIGLSGLITPSLDEMVHVAKEMERLGFDLPLLIGGATTSKAHTAVKIEQNYSHPVVYVNNASRAVGVCTSLLSDELRPAFVERLQADYELVRDQHNRKKPRTKPVTLEAARANKVAIDWQSYTPPAPSQPGVHVFDDFDVATLRQYIDWTPFFLTWSLVGKYPTIFEHEEVGEEAKRLFGDANEWLDRIEQEGLLKARGMCGLFPAASVGDDIEVYTDESRTHVAKVLHNLRQQTEKPKGANYCLSDYVAPKESGKKDWIGAFAVTGGVNERELADQFKAQGDDYNAIMIQAVADRLAEAFAEYLHERVRKEIWGYAADENLSNEELIREKYQGIRPAPGYPACPEHTEKGPLWELLNVEETIGMSLTSSYAMWPGASVSGWYFSHPDSRYFAIAQIQQDQVESYAERKGWDLLEAEKWLGPNING
What is the function of this protein?
Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine.  Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity).
What are the official names of this protein?
Methionine synthase, 5-methyltetrahydrofolate--homocysteine methyltransferase, Methionine synthase, vitamin-B12 dependent, MS.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 dependent methionine synthase family.
Protein: URE1_BLOFL
Sequence: MNMLNKKIYAEMYGPTVGDSVRLADTDLWVKIEKDFTIYGEEVKFGGGKVIRDGMGQGQMNNKECVDLVLTNAIIIDYWGVIKADIGINNGRIVGIGKSGNPDIQPGVTIYIGPGTEVISAEGKIVTAGGIDVHVHFICPQQIEEALSSGMTTLIGGGTGPTTGSNATTCTPGVWFISRMLQAADALPINIGFTGKGSSALPESLIEQIHAGAIGLKVHEDWGATPATIDCCLNVADNFDVQVSIHTDTLNESGFLETTISAIKNRTIHAYHVEGAGGGHSPDIIRICELNNVLPSSTNPTLPYTINTVDEHLDMMMVCHNLNCNLPEDIAFAESRIRRETIAAEDILHDLGALSMISSDSQAMGRIGETILRTWQTAHKMKLQRGSLLGDDQYNDNTRIKRYIAKYTINPAITHGIAHEVGSVEIGKLADLVLWSPVFFGVKPELIVKGGMIVSSVMGDPNASIPTPQPVYYRLMFGSYDLAKCATRMTFISQSSYDVGVVENLRLNSLIGISKRCRNIKKDHMINNNLKPVMEVDPQTYEVRANGELLVCEPVSVVPMSQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRDC_ECO5E
Sequence: MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELIFGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDEKMGPEPIIKSLWAVTVVATIVILFVALYW
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Fumarate reductase 15 kDa hydrophobic protein, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UVRC_RHIL3
Sequence: MNGRKLPDGGVLYDDTDESEDDIEVEGDASVAAPLAATVDWNAGSLNETGLLGAELIGEFVKRLPNSPGVYRMFNAEGDVLYVGKARSLKKRVNNYAVGRVHSNRIAQMVRQTANMEFVTTRTETEALLLEANLIKRLRPRFNVLLRDDKSFPYILITGDHRAPAIFKHRGARARKGDYFGPFASAGAVGRTINSLQRAFLIRTCTDSVFETRTRPCLLYQIKRCSGPCTHEVSDGGYGELVQEAKDFLSGKSQKVKSHMAEAMNQAAEDLDFERAAIYRDRLAALSHVQSHQGINPAGVEEADVFAIHHEGGISCIQVFFFRTGQNWGNRAYFPKADPQLSSAEVLNSFLAQFYDDKPVPKQIMLSQTVEELELLAAALSEKAGHKVSMLVPQRGEKRDLVDHVVGNAREAHGRKLAETASQSRLLEGFKETFGLAYAPQRIEIYDNSHIMGTNAVGGMVVAGPEGFVKNQYRKFNIKSTDITPGDDFGMMKEVMTRRFSRLIKEEGIPDRTAQVATPDAADMPFPTWPDVILIDGGQGQMTAVRAILAELGITDSVTAIGIAKGVDRDAGRERFFPPGRESFTLPPRDPVLYFIQRMRDEAHRFAIGSHRARRKKEMIKNPLDEIGGIGPSRKRALLQHFGTAKAVSRAALSDLMAVEGISEAVARQVYNHFHDDAAK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_VIBCM
Sequence: MSKIVKVLGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVLKALAAVNGPIADALVGKDAKDQATIDQIMIDLDGTENKSNFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGVFSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLKEAVRMGAEVFHNLAKVLKSKGYNTAVGDEGGFAPNLKSNAEALEVIAEAVAAAGYKLGTDITLAMDCAASEFYDAEKKEYNLKGEGRIFTSNGFSDFLEELTEKFPIVSIEDGLDESDWEGFAYQTEKLGKKIQIVGDDLFVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGSRAPFNGLKEVKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RNPH_RHOP2
Sequence: MRPSRRAPDELRAVSLERGVVKYAEGSCLVKFGDTHVLVTATLEERLPPWLKGQGRGWVTAEYGMLPRATLERTRREAAAGKQNGRTVEIQRLIGRSLRTIVDLQALGERQITVDCDVLQADGGTRTASITGAWVALADCLAWMKTRNMLKGQVMRDNVAAISCGIYNGTPVLDLDYAEDSEAETDANFVMTGDGRIVEVQGTAEKTPFSQDEFLALMALAQKGVARLVDLQKMAVA
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: SCRK1_ARATH
Sequence: MASNGDKGLIVSFGEMLIDFVPTESGVSLAEAPGFLKAPGGAPANVAIAVSRLGGRSAFVGKLGDDEFGHMLAGILRKNGVDDQGINFDTGARTALAFVTLRADGDREFMFYRNPSADMLLRPDELNLDLIRSAKVFHYGSISLIVEPCRSAHLKAMEVAKEAGALLSYDPNLREPLWPSKEEAKTQIMSIWDKAEIIKVSDVELEFLTGSNKIDDETALTLWHPNLKLLLVTLGEKGCRYYTKTFKGAVDPFHVNAVDTTGAGDSFVGALLNQIVDDRSVLEDEERLRKVLRFANACGAITTTKKGAIPALPSDAEVRSFLEKK
What is the function of this protein?
May play an important role in maintaining the flux of carbon towards starch formation.
What are the official names of this protein?
Probable fructokinase-1.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: IL13_HUMAN
Sequence: MHPLLNPLLLALGLMALLLTTVIALTCLGGFASPGPVPPSTALRELIEELVNITQNQKAPLCNGSMVWSINLTAGMYCAALESLINVSGCSAIEKTQRMLSGFCPHKVSAGQFSSLHVRDTKIEVAQFVKDLLLHLKKLFREGRFN
What is the function of this protein?
Cytokine that plays important roles in allergic inflammation and immune response to parasite infection (PubMed:8096327, PubMed:8097324).  Synergizes with IL2 in regulating interferon-gamma synthesis (PubMed:8096327).  Stimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells (PubMed:7903680, PubMed:8759755).  Plays an important role in controlling IL33 activity by modulating the production of transmembrane and soluble forms of interleukin-1 receptor-like 1/IL1RL1 (By similarity).  Displays the capacity to antagonize Th1-driven proinflammatory immune response and downregulates synthesis of many proinflammatory cytokines including IL1, IL6, IL10, IL12 and TNF-alpha through a mechanism that partially involves suppression of NF-kappa-B (By similarity).  Functions also on nonhematopoietic cells, including endothelial cells where it induces vascular cell adhesion protein 1/VCAM1, which is important in the recruitment of eosinophils (PubMed:8639787).  Exerts its biological effects through its receptors which comprises the IL4R chain and the IL13RA1 chain, to activate JAK1 and TYK2, leading to the activation of STAT6 (PubMed:9013879).  Aside from IL13RA1, another receptor IL13RA2 acts as a high affinity decoy for IL13 and mediates internalization and depletion of extracellular IL13 (PubMed:21622864).
What are the official names of this protein?
Interleukin-13, IL-13.
What is the protein family that this protein belongs to?
Belongs to the IL-4/IL-13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLMM_MYXXD
Sequence: MPPKEAQASQKLFGTDGVRGKANVYPMTAEVAMQLGRALAFLIRNGPHRHRVIVGKDTRLSGYMLEQALASGLTSMGVDVELVGPLPTPGISNITTSMRADAGAVISASHNPYEDNGIKFFWRDGFKLPDETEGKIEELVSSGSIDSIRPTATKIGRAFRMEDARGRYIVFLKATFPRELTLEGMTIVVDCANGAAYKTAPAVLEELGAKVIALGVSPDGKNINHKCGALYPENLAKTVVKHGAHLGIALDGDADRLIVVDEKGKVVDGDAIMAICTGELVARKQLKKKMLVSTVMSNIGLERAVARWGVKVARTRVGDRYVVDEMRRNGYNLGGEQSGHLIFLDHTTTGDGTLAALQLLAVMCRAGKPLSELASIFEPVPQTLVNVVVKQKKELGELPTVMKVIKSVEQRLGNTGRVLVRFSGTEPKARVLIEGEDAARNQAYAKEIADALSKALSV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: PSBD_LIRTU
Sequence: MTIALGRFTKEENDLFDIMDDWLRRDRFVFVGWSGLLLFPCAYFALGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGLWTFVALHGAFGLIGFMLRQFELARSVQLRPYNAIAFSAPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSAIGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: Y05F_BPT4
Sequence: MKTVTINKGMYFGKEISGTFELLGEWFPDNAPVDAQGDGKVFVEIDGKRRGVWVYKSDISYDGVKVEEVKESYEDMKTRINKRFNVMGMMTNGIINGNIRSLIISGAAGIGKTYSLDKALNKANDIGYIEYKSINGKISGIGLYEQLWNNREENSVLLIDDVDVFSDMDILNLLKAALDTGETRKVCWSTASSYLEEKGIERELEFKGTIVFITNVDIDRELDRGTKLAPHLQALVSRSVYLDLGVHTNEEIMVRVEDVILSTDMMQKRGLSDEETYKALSWMKVNVNRLRNVSLRTALYLADFIMTDKNGWEEIATGYSSEINS
What are the official names of this protein?
Uncharacterized 36.7 kDa protein in nrdC-mobD intergenic region.