PharMolix/UniProtQA huggingface dataset:
Protein: SRF1_ARATH
Sequence: MRSMRSGRDNNICFLGFLSFALISLPSLSLALTNPDDVAAINSLFLALESPLLPGWVASGGDPCGESWQGVLCNASQVETIILISANLGGELGVGLNMFTSLKAMDFSNNHIGGSIPSTLPVSLQNLFLSGNNFTGTIPESLSSLKSLSVMSLNNNLLSGKIPDVFQDLGLMINIDLSSNNLSGPLPPSMQNLSTLTSLLLQNNHLSGELDVLQDLPLKDLNVENNLFNGPIPEKLLSIPNFIKGGNLFNVTIAPSPSPETPPSPTSPKRPFFGPPSPNASAGHGQAHVRSPPSDHHPSRPTPQGKEDSFTSKRIIWISILGAFSFVVLALVCLLCGRKCLRKREDSEQLSKPHLTSEYGRAREGSRSNASMLPPSNTFNKDKEARPKERVGGASKLHGGAERSVGSESKQESHEIDMNGNAMDLMHPSSIPPIKRVIAKATEPAEASLKRTTSKSHGPLTAVKHFTVASLQQHTNSFSHENLIGTGMLGSVYRAELPGGKLFAVRKLDKKSPNHEEEGKFLELVNNIDRIRHANIVQLVGFCSEHSQRLLIHEYCRNGTLHDLLHIDDRLKIELSWNVRVRIALEAAKALEYLHEICDPPSIHRNFKSANILLDDDIRVHVSDCGLAPLISSGAVSQLSGQLLAAYGYGAPEFEYGIYTMKCDVYSFGVVMLELLTGRKSYDKKRDRGEQFLVRWAIPQLHDIDALAKMVDPSLKGDYPAKSLSHFADVISRCVQSEPEYRPLMSEVVQDLSDMIQREHRRNDSNGDNQYTGRR
What is the function of this protein?
Not essential for epidermal patterning and not redundant with STRUBBELIG.
What are the official names of this protein?
Protein STRUBBELIG-RECEPTOR FAMILY 1, Leucine-rich repeat receptor kinase-like protein SRF1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y2239_STRSV
Sequence: MTHDHNHDHEHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYVLLIPANAEEDENGEVEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFMEE
What are the official names of this protein?
UPF0473 protein SSA_2239.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: RSMC_MARMS
Sequence: MNLNSTSQLLVRNEEGLVGKILFANPEDTYPLDLSRKADVYAWCQSKTYYDALLRVGFADEKLFLSEQWALEHGSDFDHIVIYQPKAKELLDYLLASVLPLLKEGGQIWLVGDNKSGVKSSMKRLEAGLDEVGKRDGAKHCLLYTGYKRRPTKPFVFEDWITTWKQEVAGQTLTLCSLPGVFGHGKLDKGTDILLNQLNQHRFMSDVASARILDFGCGDGIIALWLHNKTGARITALDDSVMALKATELTFAANQVSDAVTLIASNGLDEVKGRFNYVVTNPPFHSGVNTDYSIAESFFMMVKQHLTLNGELFVVANDFLRYPPILDAALGSHTRLYRDRGFAIYHGRQPKKK
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_RHOPB
Sequence: MRHGKVHRKLNRTAEHRKAMFANMCASLIKHEQIVTTLPKAKELRPIVEKLVTLGKKGGLALRRQAISEMKDQDQVRKLFDVLAKRYADRQGGYTRIIKAGFRYGDNAPMAVIEFVDRDENAKGLDSGQAEEKAA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RPPH_SALDC
Sequence: MIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGESAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLLQLMSADAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMALQDNPPKLQSAPAYRRKRG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: DER_CAMJJ
Sequence: MQSIILIGKPNVGKSSLFNRMARQRIAITSDISGTTRDTNKTQIHIHSKKAMLIDSGGLDESDELFKNVKKNTLKVAKESDIILYLVDGKLAPDDEDRQFFYSLKKLGKPIALVVNKVDNKKDEERAWEFANFGVKEIFNLSVTHNVGLDELYEWLEKFLHEEFLIPDEEENLEDFLEHYEEGKEFQFKEVDQNHIRVGIVGRVNVGKSSLLNALVKQERSVVSSIAGTTIDPVNESVVHKDKVIEFVDTAGIRKRGKIQGLERFALNRTEKILSHSQIALLVLDAHEGFNELDERIAGLVAKHYLGVIIVLNKWDKSEMDFDKTVKELRLDRFKFLAYAPVISVSALSGKRVHVLLDKILQIFENFTQKIQTSKLNTLIENATRAHPLPHDYGKLVKIYYAVQYDLAPPKIALIMNRPKALHFSYKRYLQNQIRKEFNFEGVPLVIASRKKGSKENDES
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: IL22B_MOUSE
Sequence: MAVLQKSMSFSLMGTLAASCLLLIALWAQEANALPINTRCKLEVSNFQQPYIVNRTFMLAKEVSLADNNTDVWLIGEKLFRGVSAKDQCYLMKQVLNFTLEDVLLPQSDRFQPYMQEVVPFLTKLSNQLSSCHISGDDQNIQKNVRRLKETVKKLGESGEIKAIGELDLLFMSLRNACV
What is the function of this protein?
Cytokine that contributes to the inflammatory response in vivo.
What are the official names of this protein?
Interleukin-22b, IL-22b, IL-10-related T-cell-derived-inducible factor beta, IL-TIF beta, IL-TIFb.
What is the protein family that this protein belongs to?
Belongs to the IL-10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURB_MYCLB
Sequence: MKRSAVGSFFAGAHVAEAVSLAPLTTLRVGPVAQRVITCASTEQVVDVIRQLDAPAGGRGAGPLLIFAGGSNLVIADTLADLTAVRLANAGITIDGNLVRAEAGAVWDDVVVRAIEHGLGGLECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLERSSGSVRWVSACELRFGYRTSVFKQADPSGSQPPAVVLEVEFKLDASGQSAPLHYGELVATLDATSGQRANPHAVREAVLALRVRKGMVLDAADHDTWSVGSFFTNPVVAPDVYRQLAKMVDGPVPHYPAQDGVKLAAGWLVERAGFGKGYPDGAAPCRLSTKHVLALTNRGAATAEDVVTLARTVRNGVLEVFGITLEPEPALVGCVL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSB2_ORYSJ
Sequence: MECVIGVVGRDFAVVAADTSAVQSILVHKTDEDKVMVLDSHKLMGASGEPGDRVQFTEFIQKNLHLYQFRNNIPLSTAATANFTRGELATALRKNPYYVNVLLAGYDSDVGASLYYIDYIATFHKIEKGAFGYGSYFCLSLMDKLYRPDMSVEEAVDLVDKCIKEIRLRLVVAPQNFIIKIVDKEGAREYARRAYTDSPPEAATSEAATVAA
What is the function of this protein?
Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity (By similarity).
What are the official names of this protein?
Proteasome subunit beta type-2, 20S proteasome alpha subunit D, 20S proteasome subunit beta-4.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: COQ7_BURM1
Sequence: MVLDELISEFDRGLRSLTGISRMSRPVPAPAEAPAAELTPAERTHAAGLMRVNHVGEVCAQALYQAQKLTARSSAAKAMFEEAAREEEDHLAWTAHRLKELDSRPSVLNPLWYAGALAIGVAAGTLGDKVSLGFMAETERQVESHLDGHLSDLPAGDTASRAIVEQMRADEAKHGKAATDAGGIELPLPARMLMRAASKIMTRTAYYL
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GATA_CANLF
Sequence: MLGRTLREVSAALKQGQITPTELCQKCLSLIKKTKFLNAYITVSEEVALKQAEESEKRYKKGHSLGDLDGIPIAVKDNFSTSGIETTCASNMLKGYVPPYNATVVQKLLDQGAVLMGKTNLDEFAMGSGSTDGVFGPVKNPWSYSKQYKEKTKHKAHGENEDSNWLITGGSSGGSAAAVATFTCFAALGSDTGGSTRNPAAHCGVVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDAAIVLGMLAGHDPKDSTTVQDPVKPFTLPSLTDVSKLCIGIPKEYLTPELSSEVQSLWSKAANLFESEGAKVIEVSLPHTSYSIVCYHVLCTSEVASNMARFDGLEYGHRCDIDVSTEAMYAATRREGFNDVVRGRILSGNFFLLKENYENYFIKAQKVRRLIANDFVNVFNSGVDVLLTPTTLREAVPYQEFIKEDNRTRSAQDDIFTQAVNMAGLPAVSPVALSNQGLPVGLQFIGRAFHDQQLLTVAKWFEKQVQFPVTQLQELMDDCSSVFEIEKLASVSLKQ
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial, Glu-AdT subunit A, Glutaminyl-tRNA synthase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: EFS_HUMAN
Sequence: MAIATSTQLARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQACTGDPELPERGMPAPQEALSPGEPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMSSTQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAPLRAQVRAAGTALGQALRATVLAVKGAALGYPSSPAIQEMVQCVTELAGQALQFTTLLTSLAP
What is the function of this protein?
Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion.  May serve as an activator of SRC and a downstream effector.  Interacts with the SH3 domain of FYN and with CRK, SRC, and YES (By similarity).
What are the official names of this protein?
Embryonal Fyn-associated substrate, hEFS, Cas scaffolding protein family member 3.
What is the protein family that this protein belongs to?
Belongs to the CAS family.
Protein: SPC25_DEBHA
Sequence: MSTANKSPIDEFESLQSLMNDFSAKFDTALTQKRSAIINDKQLHYVKVNELKNQETQLQSDIEGLKQKEIKVKDTIKRTMEDLQMQQLKVDELARKQDSLLDEKDELQTEIDNLSSQVQTTTDSLEKSSNNLAEQLRKDYPELLKYEQHLGLKIEVIGQDSLKFVFSNIDPNDLDKEVWCELLVGGELFKVGDSFPPLAPDIITLLENEFNHHREFVKFLKTVRALLMDLI
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
What are the official names of this protein?
Probable kinetochore protein SPC25.
What is the protein family that this protein belongs to?
Belongs to the SPC25 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Protein: MFNG_MOUSE
Sequence: MHCRLFRGMAGALFTLLCVGLLSLRYHSSLSQRMIQGALRLNQRNPGPLELQLGDIFIAVKTTWAFHRSRLDLLLDTWVSRIRQQTFIFTDSPDERLQERLGPHLVVTNCSAEHSHPALSCKMAAEFDAFLVSGLRWFCHVDDDNYVNPKALLQLLKTFPQDRDVYVGKPSLNRPIHASELQSKNRTKLVRFWFATGGAGFCINRQLALKMVPWASGSHFVDTSALIRLPDDCTVGYIIECKLGGRLQPSPLFHSHLETLQLLGAAQLPEQVTLSYGVFEGKLNVIKLPGPFSHEEDPSRFRSLHCLLYPDTPWCPLLAAP
What is the function of this protein?
Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules.  Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1.
What are the official names of this protein?
Beta-1,3-N-acetylglucosaminyltransferase manic fringe, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: TEBP_RABIT
Sequence: MQPASAKWYDRRDYVFIEFCVEDSKDVNVNFEKSKLTFSCLGGSDNFKHLNEIDLFHCIDPNDSKHKRTDRSILCCLRKGESGQSWPRLTKERAKLNWLSVDFNNWKDWEDDSDEDMSNFDRFSEMMNNMGGDEDVDLPEVDGADDDSQDSDDEKMPDLE
What is the function of this protein?
Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2).  Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes.  Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.
What are the official names of this protein?
Prostaglandin E synthase 3, Cytosolic prostaglandin E2 synthase, cPGES.
What is the protein family that this protein belongs to?
Belongs to the p23/wos2 family.
Protein: CLS_ARATH
Sequence: MAIYRSLRKLVEINHRKTRPFFTAATASGGTVSLTPPQFSPLFPHFSHRLSPLSKWFVPLNGPLFLSSPPWKLLQSATPLHWRGNGSVLKKVEALNLRLDRIRSRTRFPRQLGLQSVVPNILTVDRNDSKEEDGGKLVKSFVNVPNMISMARLVSGPVLWWMISNEMYSSAFLGLAVSGASDWLDGYVARRMKINSVVGSYLDPLADKVLIGCVAVAMVQKDLLHPGLVGIVLLRDVALVGGAVYLRALNLDWKWKTWSDFFNLDGSSPQKVEPLFISKVNTVFQLTLVAGAILQPEFGNPDTQTWITYLSWLVASTTMASTAAYGVQYWKKRPISMIKRS
What is the function of this protein?
Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG).  Cannot catalyze the phosphatidyl group transfer from one PG molecule to another to form CL.  Possesses high activity with PG species carrying dioleoyl groups and low activity with species carrying one or two palmitoyl groups.  CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions.  In mitochondrial fission, CL stabilizes the protein complex of the major mitochondrial fission factors, DRP3A and DRP3B.
What are the official names of this protein?
Cardiolipin synthase (CMP-forming), mitochondrial, CLS, Phosphatidylglycerophosphate synthase 3, PGP synthase 3.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y4JG_SINFN
Sequence: MSALEDVRTVALPRDCVSTVQAHLRSVGQQGHEGMALWVGVQQDQHFVIAETVIPAQRHIRTSDGVCVMVPAEELHRLNVWLYKRGLTLLAQIHSHPGRAYHSTTDDAYAVATTIGCLSLVVPNFAREPFDFAHVAAYRLDAKANWNEVPSAVLTRMITITS
What are the official names of this protein?
Probable metalloprotease y4jG.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67B family.
Protein: RL29_SALCH
Sequence: MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQSHLLKQVRRDVARVKTLLTEKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RNPH_BORPA
Sequence: MSTSAADTLSRPSVRPAGRAVDALRPFSLERGFTRYAEGSVLVRAGNTHVLCTASVLEKVPPFLKGRGEGWVTAEYGMLPRATHTRGDREAARGKQSGRTQEIQRLIGRSLRAVFDLRLLGERTLHLDCDVLQADGGTRCASITGAWVAAADAVALLMQRGDLAHNPIRDAVAAVSVGLVDGRAVLDLDYQEDSACAADVNVVMTGSGAFVEVQGTGEGATFTRGELDTMLGLAEGGIAQLVRAQREALQ
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: NIFH1_METTM
Sequence: MVRKIAIYGKGGIGKSTTQQNTAAAMSYFHGKNVMIHGCDPKADSTRLILGGKMQTTMMDTLRELGEGACTPDKVIETGFGGIRCVESGGPEPGVGCAGRGVITAITLMERHGVYENDLDFVFFDVLGDVVCGGFAMPVRDGKAEEIYIVASGEMMALYAANNICRGMVKYARQSGVRLGGIICNSRNVDGERELLEEFCERIGTQMIHFVPRDNIVQKAEFNKKSVIEFDPECNQSQEYRELARKIIENTDFVIPEPMTMDEMEDLVVKYGVLD
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
What are the official names of this protein?
Nitrogenase iron protein 1, Nitrogenase Fe protein 1, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: FCRLA_RAT
Sequence: MKLSCMLIEWALYVCPAVLLATQMSLAASLETLKCEGPVSTEHSSCLAATEEDEGDDDMARSGEADFRFKGYTFSKPFHLIVSYDWLILQGPATSIFEGDTLVLHCRAWQDWPLTQVIFYREGSALGPPGSKSEFSIAVARKSDSGHYHCSGIFRSPGPGSQETASPVAITVQELFAAPVLKALPSSGPQEGGSVTLSCETKLSLQRSASRLLFSFYKDGRSLSSRGISSEFRIPEASEEHSGSYWCEAATEDRQISKQSPELEIRVQALQKPATPETPPPAKAPGPLPLLPTPSDEQPVFSFSDPYLTYRINRLLRQMQDVRILLGHLVMELRNLSAHRKPATTKS
What is the function of this protein?
May be implicated in B-cell differentiation and lymphomagenesis.
What are the official names of this protein?
Fc receptor-like A, Fc receptor-like and mucin-like protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Note=Seems not to be secreted.
Protein: KA292_LYCMC
Sequence: MKSVCGVLIILVVLTTMLSISTFSTVGAEADCPISEAIKCVEKCKEKVEVCEPGVCKCSG
What is the function of this protein?
Weakly inhibits the Kv1. 3/KCNA3 channel (1 uM of thetoxin inhibits currents by 13. 2%) and Kv7. 1/KCNQ1 channel (10 uM of the toxin inhibits currents by 27. 7%).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 29.2, Neurotoxin KTx3, Toxin LmKTx71.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 29 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EASK_ASPFU
Sequence: MLLLTFTLPVVTLLLAHIIRSWFRLRHIPGPFWAKITDLWREHHYIKGDYGDRPMAPYFAIPSLLGMESAMDQIQQELEDQICRRVTIDVVLWMRLFSLESLHWIAFSNKLGYLSEGKDTDGILSILQSKFIGLAGQLCGWIHRTTLRFHFPKSCTGTAVAPSQRKASHRDLLAHFMDASQKNPETLEERGVLGATISTIFAGTDTTGTSLTFFMYYLIKHPAALARLQEELDSAVRSGNLSYPPKWVEVSTLKYLQAVFKETLRLHSTARMSLYRVVGPEGLDLCGERLPSGTNLGCFGYTAHRNEPIYGRDAALFRPERWIEASNDTLLSMERASL
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of fumiclavanine C, a fungal ergot alkaloid (PubMed:15933009, PubMed:22453123).  DmaW catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4-dimethylallyl-L-tryptophan (PubMed:15870460).  The second step is catalyzed by the methyltransferase easF that methylates 4-dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methionine, resulting in the formation of 4-dimethylallyl-L-abrine (By similarity).  The catalase easC and the FAD-dependent oxidoreductase easE then transform 4-dimethylallyl-L-abrine to chanoclavine-I which is further oxidized by EasD in the presence of NAD(+), resulting in the formation of chanoclavine-I aldehyde (PubMed:20039019, PubMed:20526482, PubMed:21409592).  EasA reduces chanoclavine-I aldehyde to dihydrochanoclavine-I aldehyde that spontaneously dehydrates to form 6,8-dimethyl-6,7-didehydroergoline (PubMed:20526482).  EasG then catalyzes the reduction of 6,8-dimethyl-6,7-didehydroergoline to form festuclavine (PubMed:20526482).  Hydrolysis of festuclavine by easM then leads to the formation of fumigaclavine B which is in turn acetylated by easN to fumigaclavine A (PubMed:26972831).  Finally, easL catalyzes the conversion of fumigaclavine A into fumigaclavine C by attaching a dimethylallyl moiety to C-2 of the indole nucleus (PubMed:19672909).  The role of the cytochrome P450 monooxygenase easK within the cluster has not been identified yet (PubMed:26972831).
What are the official names of this protein?
Cytochrome P450 monooxygenase easK, Ergot alkaloid synthesis protein K.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: PKND_PARUW
Sequence: MPHSFPDYSFTCPFCKNNCKLSFAQCPAFCPFCGKSQKNESTGLPIQSDFYQIIKSIGKGGMGEVFLAYDPCYERQIAIKKIRSDLLEHPQIKKRFLKEAHMTSQLTHPAIIPIYTIRSDADTAYYTMPFVEGDTLKQIIRKTKLQEKNGETLDYLGGSILALMRVFITICQAVAYAHSKGVLHRDLKPENIIIGKYGEVLILDWGLAKFIDQSPEEELLASFPESLTKQKDITKIGKVVGTVAYMAPERALGQPATIQTDIYSLGVILYQLLTLKSPFKRGTLDEFRKNMSREEWQDPVTAAPYREVPRMLASFTEKCLSLDLQNRYQSVEELIRDIENYLEGRSEWFCIANLNTKEKNDWEFQENVLIAEHVAITRMTDDAEWVSLMISKQSFTGNTKIEADVCLGEQGHGIGFLLSVPEASAREHLIEGYCLWLGSDFSKTTKLLRSNVEVVHAPDIFLKRQQTYHVRIEKVDKSIHVYINDNLQFSYIAHIPLIGTHVGLLSRDADFEISPLEIYVGNLNINVNCLAVPDAFLAHRDYNQALSEYRRIAYSFPDRTEGREALFRAGLTFLEQAKTAENKMPLLEEALNEFEKLHGTPSAPLEYLGKALAYESINDSEEEIKCYELAYRRYPNHPILPMLQEQIISRLHEVSRMQRITTYRFTLLTVRHLPLNKIDTHTKRLFNSLQKHWEVLPFIEYKSPSPLTTLSTRFATPLAFWLAKPFILGEILDDLIQSPPFPIEEVNNALLCLVELGSWEYAQEKLNTIQTYLNLPQNPKWLDLKAFIACHYQTLEDVYKDFFFQIPSTNADHLHAVLYFMDQCLDQLNTSLIYTLARQFEHAELSFEDRLRLNCRRVWAYLLDKNWQDAGNLLYTYSVETLNKDSSLLHFLYGCWLQVTEGAEIANVHFAGVNPVMFPRTWTLGARFLTNNLSKDSYEKAFMWEKRQLCKQLILYYHCVGNETKRIHFQKLYQEQFIHAEL
What is the function of this protein?
Together with the serine/threonine kinase Pkn1, may play a role in the specific interactions with host proteins during intracellular growth.
What are the official names of this protein?
Serine/threonine-protein kinase PknD.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: LPXA_XANC8
Sequence: MRDQAPLIHPTAVIDPAARLASDVRVGAFSLIGADVEIGAGTEVGPHCSIHGPTRIGSNNRFIGHAAIGGEPQDKKYAGERTELVIGNGNVIREFVTINRGTGGGGGITVVGDDNWMLAYTHVAHDCHVGNHCVFSNNTTLAGHVTVGDYVIISGFAGAHQFCRIGAHAFLGMGALTNGDVPPFTMVGSDSLGRPRGINSEGLKRRGFDAERISAIKRAYRTLYVAGLPLAEAKLQLAEQARDSDDVRGLLEFIEAAERPLLR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REX_BACVZ
Sequence: MNKDQSKIPQATAKRLPLYYRFLKNLHASGKQRVSSAELSDAVKVDSATIRRDFSYFGALGKKGYGYNVDYLLSFFRKTLDQDETTNVILIGVGNLGTAFLHYNFTKNNNTKISMAFDVNQSKIGTEVGGVPVFDLNDLELHIKDEPVAILTVPAVAAQSITDRLVSLGIKGILNFTPARLNVPDHIRIHHIDLAVELQSLVYFLKHYSVLEEIE
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_VIBCM
Sequence: MNAKFIVIEGLEGAGKSTAIQVVVETLQQNGIDHITRTREPGGTLLAEKLRALVKEEHPGEELQDITELLLVYAARVQLVENVIKPALARGEWVVGDRHDMSSQAYQGGGRQIAPSTMQSLKQTALGDFKPDLTLYLDIDPKLGLERARGRGELDRIEKMDISFFERARERYLELANSDDSVVMIDAAQSIEQVTADIRRALQDWLSQVNRV
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.