PharMolix/UniProtQA huggingface dataset:
Protein: COPG2_TAKRU
Sequence: MIKKFDKKDEESGSGSNPFQNLEKSAVLQEARIFNETPINPRRCLHILTKIIYLLNQGEHFGTTEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMANISEDVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDTTMLQAIERYMKQAIVDKVPSVSSSALVSSLHMVKMSYDVVKRWVNEAQEAASSDNIMVQYHALGLLYHLRKNDRLAVTKMLNKFTKSGLKSPFAYCMLIRIASKLLDETEAGHDSPLFDFIESCLRNKNEMVVYEAASAIVHMPNCTARELAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQAISALCQKYPRKHSAMMNFLSNMLRDDGGFEYKRAIVDCIISIIEENPESKETGLAHLCEFIEDCEHTVLATKILHLLGKEGPRTPQPSKYIRFIFNRVVLESEAVRAAAVSALAKFGAQNDDLLPSVLVLMQRCMMDSDDEVRDRATFYMNVLQQKQKALNAAYIFNGLSVSIPGLEKSLHQYTLEPSEKPFDMKSVPLATTPITEQKTEIAPAATSKLPEKLAPSRQDIYQEQLAAIPEFQGLGPLFKSSDPVQLTEAETEYVVRCIKHTFARHMVFQFDCTNTLNDQLLQKVLVQMEPSEAYEVIHYIPAPSLPYSQPGSCYSLVRLPDDDPTAVSCTFSCTMKYLVRDCDPNTGEPDDDGYDDEYVLEDLEVTVPDHIQKVLKPNFGAAWEEVGDEFEKEETFALASVRTLDEAVGNIISFLGMQPCERSDKVPENKNSHVLFLAGVFRGGHDVLVRARLALADGVTMQVTVRSSEETVVDVILASVG
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
What are the official names of this protein?
Coatomer subunit gamma-2, Gamma-2-coat protein, Gamma-2-COP.
What is the protein family that this protein belongs to?
Belongs to the COPG family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SURE_RUTMC
Sequence: MKILISNDDGYQAPGIVQLAQSLTQEHEIIVVAPSENKSASSSSLTFDNPLRPIQISNNVYKIDATPSDCVHLALCGFLNEKIDLVVTGINFGANLGDDVIYSGTVAGAIEGRFLGLPSVAISLASWKGQHFETAGIIAKQLINQISHTQLSHDTVLNVNVPDVSLNYIKGFQTTRLGKRHMSEQSVADKDDPTLYWIGENGKEADNGVGTDFHAIANYYVSVTPLQIDLTKYNEIDTVSKWLNQIK
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_STRTD
Sequence: MKKFLIALVKAYQRWISPLFPLSCRFCPTCSVYMIQAIEKHGLKGVLMGIARILRCHPLSETGDDPVPDYFSLKRKKTPLDN
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AAEX_ERWT9
Sequence: MSVLPVVVVFGMSFPPIFIEIIVSLMLFWLIRRAITPTGLYDLVWHPALFNTALYCCLFYVVSRLFV
What are the official names of this protein?
Protein AaeX.
What is the protein family that this protein belongs to?
Belongs to the AaeX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MENG_ROSCS
Sequence: MNTNVLPPPDQKAEYVERMFSRIASGYDTMNGIMTLGLDRGWRTATVALAAPPSCGRALDIGTGTGDFLVELAQWMPDGLAVGVDFTLPMMRAGLPKIAGQRAVFVAGDALALPFDDESFDAITTGFTLRNVTDIAAAFREMWRVARVGGTVACLEVARPRQPLLRFGHWVYFQRIVPLMARALGADPEAYTYLPQSARVFPPPDELAQIMREAGWSDVTYRLVGLGAAAIHTGIKRG
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: DML1_ASHGO
Sequence: MREIVTITASHRANHLITQFFNGQERALHERDEQAGSDPSVFLHGTIDADGRTMSYEPRAVLWDAKGGSGALGRFQYWSQDDYADEEEPPRAAPGIEVVQTAARVRRSAYQRALDAGEAPPALTAAGARYWSDYGRMIYGQDSVQELAHWHHDVAAPSAPDFEALGQRRFDRYENGYEVFTEECARDFFDISLHRQLEQCDTLQGFNLVTETDNGWGGFMAALQEQLREEVPKVCYFGWGLNVDESGPRHPPRAGFQRQSNKLRATLAMLEQSDLYFPIRSEAADSLWEAGGWACHVLDSVNSAMCLEKSRTLRFMNQLADRLHSGDEQRNVVSLMSSGQRSYSYFADAPRHRSSRGDPHTFSRCRLLRGSHSPPETTLSVENLELIRTYAWRPADTIPETARNLHHIDLGVTEKCRDVFKNWYEMVAKQFRYDPDREELKERLGTLGAAYECGWYSDDDSGDDT
What is the function of this protein?
Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.
What are the official names of this protein?
Protein DML1.
What is the protein family that this protein belongs to?
Belongs to the misato family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SOXD_RHIME
Sequence: MASLVPCPNCGRRPKEEFTIKGAALSRPEADADSIDWFDYVYLRENPRGAYEEYWHHTSGCRRWLVVARDTVTHEIAACCDAAGRARSEARK
What is the function of this protein?
Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10-methylenetetrahydrofolate.
What are the official names of this protein?
Sarcosine oxidase subunit delta, Sarcosine oxidase subunit D.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTMRD_HUMAN
Sequence: MARLADYFIVVGYDHEKPGSGEGLGKIIQRFPQKDWDDTPFPQGIELFCQPGGWQLSRERKQPTFFVVVLTDIDSDRHYCSCLTFYEAEINLQGTKKEEIEGEAKVSGLIQPAEVFAPKSLVLVSRLYYPEIFRACLGLIYTVYVDSLNVSLESLIANLCACLVPAAGGSQKLFSLGAGDRQLIQTPLHDSLPITGTSVALLFQQLGIQNVLSLFCAVLTENKVLFHSASFQRLSDACRALESLMFPLKYSYPYIPILPAQLLEVLSSPTPFIIGVHSVFKTDVHELLDVIIADLDGGTIKIPECIHLSSLPEPLLHQTQSALSLILHPDLEVADHAFPPPRTALSHSKMLDKEVRAVFLRLFAQLFQGYRSCLQLIRIHAEPVIHFHKTAFLGQRGLVENDFLTKVLSGMAFAGFVSERGPPYRSCDLFDELVAFEVERIKVEENNPVKMIKHVRELAEQLFKNENPNPHMAFQKVPRPTEGSHLRVHILPFPEINEARVQELIQENVAKNQNAPPATRIEKKCVVPAGPPVVSIMDKVTTVFNSAQRLEVVRNCISFIFENKILETEKTLPAALRALKGKAARQCLTDELGLHVQQNRAILDHQQFDYIIRMMNCTLQDCSSLEEYNIAAALLPLTSAFYRKLAPGVSQFAYTCVQDHPIWTNQQFWETTFYNAVQEQVRSLYLSAKEDNHAPHLKQKDKLPDDHYQEKTAMDLAAEQLRLWPTLSKSTQQELVQHEESTVFSQAIHFANLMVNLLVPLDTSKNKLLRTSAPGDWESGSNSIVTNSIAGSVAESYDTESGFEDSENTDIANSVVRFITRFIDKVCTESGVTQDHIKSLHCMIPGIVAMHIETLEAVHRESRRLPPIQKPKILRPALLPGEEIVCEGLRVLLDPDGREEATGGLLGGPQLLPAEGALFLTTYRILFRGTPHDQLVGEQTVVRSFPIASITKEKKITMQNQLQQNMQEGLQITSASFQLIKVAFDEEVSPEVVEIFKKQLMKFRYPQSIFSTFAFAAGQTTPQIILPKQKEKNTSFRTFSKTIVKGAKRAGKMTIGRQYLLKKKTGTIVEERVNRPGWNEDDDVSVSDESELPTSTTLKASEKSTMEQLVEKACFRDYQRLGLGTISGSSSRSRPEYFRITASNRMYSLCRSYPGLLVVPQAVQDSSLPRVARCYRHNRLPVVCWKNSRSGTLLLRSGGFHGKGVVGLFKSQNSPQAAPTSSLESSSSIEQEKYLQALLNAVSVHQKLRGNSTLTVRPAFALSPGVWASLRSSTRLISSPTSFIDVGARLAGKDHSASFSNSSYLQNQLLKRQAALYIFGEKSQLRNFKVEFALNCEFVPVEFHEIRQVKASFKKLMRACIPSTIPTDSEVTFLKALGDSEWFPQLHRIMQLAVVVSEVLENGSSVLVCLEEGWDITAQVTSLVQLLSDPFYRTLEGFQMLVEKEWLSFGHKFSQRSSLTLNCQGSGFAPVFLQFLDCVHQVHNQYPTEFEFNLYYLKFLAFHYVSNRFKTFLLDSDYERLEHGTLFDDKGEKHAKKGVCIWECIDRMHKRSPIFFNYLYSPLEIEALKPNVNVSSLKKWDYYIEETLSTGPSYDWMMLTPKHFPSEDSDLAGEAGPRSQRRTVWPCYDDVSCTQPDALTSLFSEIEKLEHKLNQAPEKWQQLWERVTVDLKEEPRTDRSQRHLSRSPGIVSTNLPSYQKRSLLHLPDSSMGEEQNSSISPSNGVERRAATLYSQYTSKNDENRSFEGTLYKRGALLKGWKPRWFVLDVTKHQLRYYDSGEDTSCKGHIDLAEVEMVIPAGPSMGAPKHTSDKAFFDLKTSKRVYNFCAQDGQSAQQWMDKIQSCISDA
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) which activates RAB21 and possibly RAB28 (PubMed:20937701, PubMed:25648148).  Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (PubMed:20937701, PubMed:25648148).  In response to starvation-induced autophagy, activates RAB21 which in turn binds to and regulates SNARE protein VAMP8 endolysosomal transport required for SNARE-mediated autophagosome-lysosome fusion (PubMed:25648148).  Acts as an adapter for the phosphatase MTMR2 (By similarity).  Increases MTMR2 catalytic activity towards phosphatidylinositol 3,5-bisphosphate and to a lesser extent towards phosphatidylinositol 3-phosphate (By similarity).
What are the official names of this protein?
Myotubularin-related protein 13, Inactive phosphatidylinositol 3-phosphatase 13, SET-binding factor 2.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
Protein: RSMH_CLOBH
Sequence: MEFKHISVLLEETIDSLNIKEDGVYVDCTLGGGGHSKEILKKLSHKGKLIGIDQDTSAIKAAKERLKDYENVIYVHNNFYNIDSILEELDIDKVDGIIMDLGVSSYQLDEASRGFSYMKDAPLDMRMNREENLSAYGVINNYEEEELFKILKNYGEEKFSRKIARFIVEKRTENPIETTGELVEIIRKAIPAKFQREGHPAKRTFQAIRIEVNKELQILNKAIEDSVNRLNKDGRLSIITFHSLEDRIVKVKFKELEKPCTCPPSFPICVCGKEPQIKIITKKPIEPSKEEKEINSRSRSAKLRVCRKI
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_METEP
Sequence: MAQNGSEGPLLAGVAGRYALALYELAHDQGQVDDVAKNLDAFDALYRESDDLRRLVRSPAYSAAEQTAAVGALLDRAGISGLAANFIKLTADNRRLFALPGMIRAYREKVRESKGIIRAEVRVAEKPSDAVIEDIKASLRDVAKSEIDLDLHIDPSLIGGIVVKMGSRMVDASLRTKLNSIRLAMREAR
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ATPG_ANASK
Sequence: MPSLRDIRNRIGSVRSTRQITKAMKMVSAAKLRRAQDAVLKTRPYAVLLDQTLSRLAARAAAEEQVAHPLLAPRAQRTAEVVVVTSDRGLAGGFNSNICRFVQRFLTENADRFERIALSTVGKKGREYFKARRLEIRKDYTGVHANLAYEKAEALAREATERYLAGEVDAVFLAYNEFKSAISQKQVVVQLLPIDTSAAGADATGIDFKYEPSREALLAELLPRHVAMQVWRALLESAASEHGARMSAMESATKNAEEMIASLSLQYNRARQAYVTKELMEIVGGAEALK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y752_MYCBO
Sequence: MTQTGSARFEGDSWDLASSVGLTATMVAAARAVAGRAPGALVNDQFAEPLVRAVGVDFFVRMASGELDPDELAEDEANGLRRFADAMAIRTHYFDNFFLDATRAGIRQAVILASGLDSRAYRLRWPAGTIVFEVDQPQVIDFKTTTLAGLGAAPTTDRRTVAVDLRDDWPTALQKAGFDNAQRTAWIAEGLLGYLSAEAQDRLLDQITAQSVPGSQFATEVLRDINRLNEEELRGRMRRLAERFRRHGLDLDMSGLVYFGDRTDARTYLADHGWRTASASTTDLLAEHGLPPIDGDDAPFGEVIYVSAELKQKHQDTR
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase Mb0752c.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: HCY3_PANJA
Sequence: DAHGSGNAHKQQDINHLLD
What is the function of this protein?
Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods.
What are the official names of this protein?
Hemocyanin subunit III.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family. Hemocyanin subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: E3GL_ADE1P
Sequence: MGPILVLLVLLSLLEPGSANYDPCLDFDPENCTLTFAPDTSRICGVLIKCGWECRSVEITHNNKTWNNTLSTTWEPGVPEWYTVSVRGPDGSIRISNNTFIFSEMCDLAMFMSKQYSLWPPSKDNIVTFSIAYCLCACLLTALLCVCIHLLVTTRIKNANNKEKMP
What is the function of this protein?
Binds and retains class I heavy chains in the endoplasmic reticulum during the early period of virus infection, thereby impairing their transport to the cell surface.  Also delays the expression of class I alleles that it cannot affect by direct retention.  Binds transporters associated with antigen processing (TAP) and acts as a tapasin inhibitor, preventing class I/TAP association.  In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes (By similarity).
What are the official names of this protein?
Early E3 18.5 kDa glycoprotein, E3-19K, E3gp 19 kDa, E19, GP19K.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E19 family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: RS19_STRPJ
Sequence: MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: GLMM_RUTMC
Sequence: MDNYFGTDGMRGKVGVEPITADFFLKLGWAVGSVLAKRAKASVIIGKDTRVSGYLFESALEAGFLSAGVDVGLLGPMPTPAVAYLTQTYNASAGVVISASHNNFQDNGVKFFSAKGLKLSSQYQSEIEKKLAETMISVGADKIGKAYRYEQPLGRYIEFCKSTFDRTQSLLGLNIVIDCANGATYHIAQSVFSELGANINIINNTPDGFNINEHCGATDTKYLQQVVLESKADLGIAFDGDGDRLIMIDENGELVDGDELVFIIAKAWQSQGRLVNNTVVGTKMSNLGMHHALRDLDIKFIEADVGDRFVMEKMQKSGSILGGEGSGHIICLNKTTSGDGIISALQVLEVLVKSQSSLAKLKQSMEKYPQILINVKTQARINLKNYTKLQRTQLAVEQTLGDESRVLIRVSGTEPLIRVMVEAKDKIIAQQGAEKLSNIFK
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: HIS8_ALIFM
Sequence: MEKLARKQVQALTPYLSARRIGGSGDVWLNANESPFDNEYKFNFARLNRYSECQPPELINAYAAYAEVKPEQVLTSRGADEGIELLVRAFCEPNQDAILYCPPTYGMYSISAETIGVETKTVPLTSDWQLDLPAIEASLENVKVVFVCSPNNPTGNIVDRKDILSLLEMTKDRAIVVMDEAYIDFCMEKSTVDLLADYPHLAILRTLSKAFALAGLRCGFTLANEELINVLLKVIAPYPVPVPVAEIATQALSEAGLARMKYQMLDLSANRAYLQAGLMVLPGVTVYEGWGNYLLVKFTNGDAVFKAAWDHGIILRNSPIENCVRISVGNREECEKTLGFIRNQLI
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: DTD_GEOSW
Sequence: MRVVVQRAKHAKVTVNGEVVGSIDHGLVLLVGVTHSDTVEDAAFIADKIAHLRIFEDESGKMNLSVLDVGGEILSVSQFTLYGDCRKGRRPNFMEAAKPDRALPIYEAMNEALRQKGIRVETGKFGAMMEVELINDGPVTLIVESKEKAGNK
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NNR_THEPD
Sequence: MKVARVSEIKLLDREAAEKYGVKEEILMENAGASVARLAVSLIGLPMSAAVVCGPGNNGGDGLVAARHLSSMGADVKVFLVAAPDKLAGIVKENYERVVKAGIAVEVVDEERAEGLSEELSLFDVVVDALFGTGLSRPLEGVYRKVVEAINGSGSLVISVDIPSGVHGDTGQVLGVAVRADYTVTFGLPKLGNLMYPGAELGGELYVHHISYPRALLEDSRLKVETNDPVPLPPRRPDTHKGDYGKALFVAGSRRYMGAPLLCSKSFLKAGGGYSRLATIKSIVPFLGVRAPEVVYEALEETASGTVAYGNLERILELSKSSDIVAVGPGLGLEEETLRLVCDLARSVEKPLIVDGDGLTAVARCGEYISERRAPTVLTPHAGEMSRLTGKSVEEVRASRVDAALELAGKLKAYVVLKGAHTVIATPDGRAYINLSGNPGMATAGSGDVLVGAIAALYGLGLGFEEAVRMGVFVHGLAGDIAAEERGQDGLTSVTLMNYLPKALRALREDFESVLERYTIKVLP
What is the function of this protein?
Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP.  This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity).
What are the official names of this protein?
Bifunctional NAD(P)H-hydrate repair enzyme Nnr, Nicotinamide nucleotide repair protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NnrD/CARKD family.
Protein: ILVC_SALAR
Sequence: MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVINLTPDKQHSDVVRSVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKAIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIAEGSVDNAQLRDVNDAIRSHAIEKVGQKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: RBFA_CORGB
Sequence: MADNARAARMAKRIQTIVASAIERDIKDRRLEFVTITDVTMTGDLHDAKVFYTVRGASIEEEPDLEAAAEALHRARGQLRKIVGQQLGVRFTPTLTYSIDTVPEASAHMEALLDRARKRDEELAKLREGAVPAGDADPYKTSSKSESEE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y230_STAEQ
Sequence: MKVFIILGALNAMMAVGTGAFGAHGLEGKLSDKYMSIWEKATTYQMYHGLGLLVIGLISGTTSINVNWAGWLLFFGIVFFSGSLYFLALTQVRILGAITPIGGVLFIIGWLVLVIATLKFAG
What are the official names of this protein?
UPF0382 membrane protein SERP0230.
What is the protein family that this protein belongs to?
Belongs to the UPF0382 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS6_RHOCB
Sequence: MLKTRIIPCLDVADGRVVKGVNFVNLIDAGDPVEAAKAYDAAGADELCFLDIHATHENRGTMFDLVTRTAEQCFMPLTVGGGVRTQEDVRALLLAGADKVSFNSAAVANPDVVAEAADRFGSQCIVVAIDAKTVEPGRWEIFTHGGRKSTGIDAVEFARHVEAKGAGEILLTSMDRDGTKAGFNLPLTRAIADAVKIPVIASGGVGTLDHLVEGVTEGHASAVLAASIFHFGTYTIGEAKAHMAAAGIPMRLA
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_SINMW
Sequence: MSRRHRAEKREINPDPKFGDLVVTKFMNAIMLHGKKSVAESIVYGAFDAVQSKLKQEPVTVFHSALDNIAPHVEVRSRRVGGATYQVPVDVRPERRQALAIRWLIAAARKRNETTMVDRLCGELMDAANNRGSAVKKREDTHKMADANRAFSHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: CT13_CONTE
Sequence: MRCLPVFVILLLLIASVPSDAVQLKTKDDMPLPSFNGNARRTPRMLSNKRICCYPNVWCCD
What are the official names of this protein?
Conotoxin 3.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
Protein: AMPC_PSEAE
Sequence: MRDTRFPCLCGIAASTLLFATTPAIAGEAPADRLKALVDAAVQPVMKANDIPGLAVAISLKGEPHYFSYGLASKEDGRRVTPETLFEIGSVSKTFTATLAGYALTQDKMRLDDRASQHWPALQGSRFDGISLLDLATYTAGGLPLQFPDSVQKDQAQIRDYYRQWQPTYAPGSQRLYSNPSIGLFGYLAARSLGQPFERLMEQQVFPALGLEQTHLDVPEAALAQYAQGYGKDDRPLRVGPGPLDAEGYGVKTSAADLLRFVDANLHPERLDRPWAQALDATHRGYYKVGDMTQGLGWEAYDWPISLKRLQAGNSTPMALQPHRIARLPAPQALEGQRLLNKTGSTNGFGAYVAFVPGRDLGLVILANRNYPNAERVKIAYAILSGLEQQGKVPLKR
What are the official names of this protein?
Beta-lactamase, Cephalosporinase.
What is the protein family that this protein belongs to?
Belongs to the class-C beta-lactamase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CNBD2_MOUSE
Sequence: MNRSANPEAASSTSHVKFDLGKSVDISSTDTKDGGTARSPLEPADKSDTTESKSESGSDSRSEEDKESPASIKEIKAETPQPKDRPGVQIKLSWSQKIKSWTAKKKRKLYQLVIDIIMMNRVCKMFRQGLRGFREYQIIEPVHKKHPDFSFWDKKKQGRISFVTEDFAAQEGHFPPRAISITQKKPSWRTHQEIQDLCNILQALDCYRSYTESLQLLLAKVIRFERFGRRRVIVKKGQMGNSFYFIYLGTVAITEDEDGSSAFLDPHPTLLHRGGSFGEMGLLSTTVRSATVVCMEETEFLVVDREDFVANKLGDEVQKETQYRYNFFRNLDIFQSWSEEKLWKLVALGRIERFSYGQMVSKDFMNSAFITFICQGNCEILRLVALGDCSAYYKWVWQQLELLDHKPLRIHDNEISPKERFKELQIKSYPLQDFTYLKLLRLQKAREQQGIDFHGKINKVENTLPKLLGPKIKSRFGHLVKCSMVNTKFGELPKEAIVGVYMKIHKTEEGEIVGLHQAFVPEIQRDCRPFILLSLGSELIQVRKEKFYDMVDEETRAKIIKMDVDYPSDEDLCQSFLKENDYIVFRKDLLRLLVEPLNKSPFIPVQTKKKEIYNHKSLFLDLCSLEKKVKQHYPIFLAPQKYLPPLRVVQAISAPRHKIQELLPQYKNAGVLI
What is the function of this protein?
Essential for male fertility.  Plays an important role in spermatogenesis and regulates sperm motility by controlling the development of the flagellar bending of sperm (PubMed:24339785).
What are the official names of this protein?
Cyclic nucleotide-binding domain-containing protein 2, Cyclic nucleotide receptor involved in sperm function.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.