PharMolix/UniProtQA huggingface dataset:
Protein: CDYL_RAT
Sequence: MGLGSSQPSTKEAEPCTLQEKEEHPVDDTRQQNNAVPATVSDPDQVSPAVQDAETQVESIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHDFNRRHNERQKEGTLARANRASPSNARKQISRSTHSALSKTNPKALVVGKDHESKTNQLLATSQKFRKNTAPSLANRKNMDLAKSGIKILVPKSPIKGRTSIDGFHGESPEKLDQGAEDTVTPEVTAEKPTGALLGPGAERARMGSRPRIHSLVPQVSGPVTAAMATTLAVNGKGTSPFMDALTANGTVTIQTSVTGVTAGKRKFIDDRRDQPFDKRLRFSVRQTESAYRYRDIVVRKQDGFTHILLSTKSSENNSLNPEVMKEVQSALSTAAADDSKLVLLSAVGSVFCCGLDFIYFIRRLTDDRKRESTKMAEAIRNFVNTFIQFKKPIIVAVNGPAIGLGASILPLCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLLSGRKLTAQEACGKGLVSQVFWPGTFTQEVMVRIKELASCNPIVLEESKALVRCNMKMELEQANERECDALKKIWGSAQGMDSMLKYLQRKIDEF
What is the function of this protein?
Not able to recognize and bind histone H3K9me3, histone H3K27me2 and histone H3K27me3, due to the presence of a N-terminal extension that inactivates the chromo domain.
What are the official names of this protein?
Chromodomain Y-like protein, CDY-like, Crotonyl-CoA hydratase, Putative tubulin acetyltransferase Cdyl.
What are the subcellular locations of this protein?
[Isoform 2]: Nucleus. Chromosome. Note=Recognizes and binds histone H3 trimethylated at 'Lys-9', dimethylated at 'Lys-27' and trimethylated at 'Lys-27' (H3K9me3, H3K27me2 and H3K27me3, respectively) on chromatin. Multimerization is required for chromatin-binding. Recruited to sites of DNA double strand breaks in a PARP1-dependent fashion (By similarity).
Protein: PHE1_ARATH
Sequence: MRGKMKLSFIENDSVRKTTFTKRKKGMLKKFNELVTLCGVDACAVIRSPYNSIQEPWPSREGVEEVMSKFMEFSVLDRTKKMVDQETFLRQRIAKETERLQKLRDENRNSQIRDLMFGCLKGEVDVSHLHGRDLLDLNVFLNKYLNGVIRRVEILKENGESSSSVPPPIGVAPTVVDASVPIGFDGRMIQDQNQNQQEPVQFQYQALYDFYDQIPKKLHDFNMKMNIDPNQSMNLDLNDGEDEGIPCMDNNNYHPEIDCLATVTTAPTDVCAPNIINDL
What is the function of this protein?
Probable transcription factor involved in the development of gametophytes and seeds.
What are the official names of this protein?
MADS-box transcription factor PHERES 1, Agamous-like MADS-box protein AGL37.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASNA_STRPZ
Sequence: MKKSFIHQQEEISFVKNTFTQYLIAKLDVVEVQGPILSRVGDGMQDNLSGTENPVSVNVLKIPNATFEVVHSLAKWKRHTLARFGFNEGEGLVVNMKALRPDEDSLDQTHSVYVDQWDWEKVIPDGKRNLAYLKEAVETIYKVIRLTELAVEARYDIEAVLPKKITFIHTEELVAKYPDLTPKERENAITKEFGAVFLIGIGGVLPDGKPHDGRAPDYDDWTTETENGYHGLNGDILVWNGQLGSAFELSSMGIRVDEEALKRQVEMTGDQDRLAFDWHKSLLNGLFPLTIGGGIGQSRMVMFLLRKQHIGEVQTSVWPQEVRDSYDNIL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_RHIE6
Sequence: MMENNRNYFIAIALSVLIVLGWQFLYMNPRIEAQRKAQEAQKAQQQTEQVQQPAAGGATPAPASGTAPSGQAVATATLEQALAKTPRVAIDTPALSGSINLAGARLDDLKLKGYHETVDDSSPIITLFSPAETKDGYFTELGYIGSDATGSVPGASTLWTAPEGAKLTEKTPVTLSYTNDKGLTFTRTISVDERYMFTIADKVANTGQAPVSLSSYGRVTRYNKPTTPSAYVLHEGFIGVIGDDGLIESKYTAVEKEAVMPAKSTGGWLGITDKYWAATIVPPQASAYEARFSHFSDGQPRYQADYKDDAFTVAPGQSVELKNLVFAGAKEVPVIDGYEASYSIPRFDRLIDWGWFYFITKPMFKLMDFFFRFFGNFGVAILCTTIVVKALFFPLASKQYASMANMKRMQPKMEELKAKFGDDRMGLQQATMQLYKEEKINPIAGCWPVALQIPIFFSLYKVIYITIEMRHAPFFGWIQDLSAPDPTTIVNLFGLLPFTAPTFLHLGVWPLIMGVTMFLQMRMNPTPPDPTQAMIFNWMPLVFMFMLASFPAGLVIYWAWNNTLSVIQQSVIMKRHGVKIELFDNLKGLFRRKTAPSK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RECA_BORPA
Sequence: MDDKTSKAAAAEKAKALAAALSQIEKQFGKGSIMRYGDNEVEHDIQVVSTGSLGLDIALGVGGLPRGRVIEVYGPESSGKTTLTLQVIAEMQKLGGTCAFVDAEHALDVQYASKLGVNLTDLLISQPDTGEQALEITDALVRSGSVDLIVIDSVAALVPKAEIEGEMGDSLPGLQARLMSQALRKLTATIKRTNCMVIFINQIRMKIGVMFGNPETTTGGNALKFYSSVRLDIRRIGAIKKGDEVVGNETRVKVVKNKVAPPFKQAEFDIMYGSGISREGEIIDLGVQANVVDKSGAWYSYSGNRIGQGKDNVREYLKEHKEMAIEIENKVRENQGIVSRAATFPASEAEDGE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CIPK9_ORYSJ
Sequence: MAEAEAEAAGAGAGAGPARRTTRVGRYELGKTIGEGSFAKVKVARDTRTGDTLAIKVLDRNHVLRHKMVEQIKREISTMKLIKHPNVVQLHEVMASKSKIYMVLEYVDGGELFDKIVNSGRLGEDEARRYFHQLINAVDYCHSRGVYHRDLKPENLLLDSHGALKVSDFGLSAFAPQTKEDGLLHTACGTPNYVAPEVLADKGYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLICKAKVSCPHWFSSGAKKFIKRILDPNPCTRITIAQILEDDWFKKDYKPPLFEQGEDVSLDDVDAAFDCSEENLVAEKREKPESMNAFALISRSQGFNLGNLFEKEMMGMVKRETSFTSQCTPQEIMSKIEEACGPLGFNVRKQNYKMKLKGDKTGRKGYLSVATEVFEVAPSLHMVELRKTGGDTLEFHNFYNNFSSELKDIVWKSESDAKAAKKR
What is the function of this protein?
CIPK serine-threonine protein kinases interact with CBL proteins.  Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity).
What are the official names of this protein?
CBL-interacting protein kinase 9, OsCIPK09.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Protein: CLUA1_MOUSE
Sequence: MSFRDLRNFTEMMRALGYPRHISMENFRTPNFGLVSEVLLWLVKRYEPQTDIPSDIETEQDRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSNVGEEDISKFKFDLGSKIADLKAARQLASEITAKGASLYDLLGKEVELRELRTEAIARPLEINETEKVMRIAIKDLLAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQSVRPAFMDEYEKVEEDLQKQYDVYLEKFRNLAYLEQQLEDHHRMEQERFEEAENTLRLMQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEDRRMSKPRTAMEVLMQGRPSKRIVGAMQGGDSDEDEDSEDSEIDMEDDEEDDDDLEDESIALSPAKPSRRIRKPEPLDESDNDF
What is the function of this protein?
Required for cilia biogenesis.  Appears to function within the multiple intraflagellar transport complex B (IFT-B).  Key regulator of hedgehog signaling.
What are the official names of this protein?
Clusterin-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the CLUAP1 family.
What are the subcellular locations of this protein?
Cell projection, cilium. Nucleus.
Protein: HCAF_ECO24
Sequence: MSAQVSLELHHRISQFLFHEASLLDDWKFRDWLAQLDEEIRYTMRTTVNAQTRDRRKGVQPPTTWIFNDTKDQLERRIARLETGMAWAEEPPSRTRHLISNCQISETDIPNVFAVRVNYLLYRAQKERDETFYVGTRFDKVRRLEDDNWRLLERDIVLDQAVITSHNLSVLF
What is the function of this protein?
Part of the multicomponent 3-phenylpropionate dioxygenase.  Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively.
What are the official names of this protein?
3-phenylpropionate/cinnamic acid dioxygenase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.
Protein: RNH2_PSYIN
Sequence: MSKLKIDFPAVVYPDFTLIAGVDEVGRGPLVGDVVTACVILDANNPISGLADSKKLSEKKLALLFDEIQEKALFVAVGRASPVEIDALNILHATMLAMQRAVDNLSISPEFVFIDGNRCPQLSMPCESVVKGDARVAEISAASIIAKVTRDREMCELDKQYPHYGFAKHKGYPTKAHFAAIEKHGVTPEYRKSFKPVKKVLGLL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM6_RICTY
Sequence: MNTENKEITSNWFTNLRDLLCKEFEKIEEKYAQIKGLKPAKFVRTSWKRNGGGCGIMSLMKGEVFEKVGVNISTVFGEFSQEFRSEILGAELDGKFFATGISVVAHLKSPLIPAMHFNTRYIETSKNWFGGGSDLTPFYPEENETAKFHTAFKEACDKYDSSYYPKFKRQCDEYFYLRHRKEPRGVGGIFYDYLNSGNFEQDFAFTRDIGKALLSVYPEIVRSKLFLPWTDEQKEYQLIKRGRYVEFNLLYDRGTKFGLMTDGNIEAILMSLPPVVKFN
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_SALHS
Sequence: MAKLTKRMRVIREKVDATKQYDINEAIALLKELATAKFNESVDVAVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGPNAEAAKAAGAELVGMEDLADQIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPSQAKGVYIKKVSISTTMGAGVAVDQAGLSASAN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: LEUD_GRABC
Sequence: MDKFTVLTAIAAPLPVANVDTDKIIPARFLKTIKRTGLGTHLFDAMRYIDGQENPDFVLNREPYRQAQILVTHENFGCGSSREHAPWALLDFGIRCVIAPDFADIFYNNSFKNGILPIRLPRDICDRLMDDAGNGANSRLTVDLERQVVVRPNGEEIPFEIDPFRRHLLLNGLDDIGQTLQRREAIDRFEENRTVTQPWFPRITLPAN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: CH10_PARMW
Sequence: MAAVSLSVSTVKPLGDRVFIKVSESEEKTAGGILLPDTAKEKPQVGEVVQVGPGKRNDDGSRQAPEVGVGDKVLYSKYAGTDIKLGGDEFVLLTEKDILAIVN
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PT3_HUMAN
Sequence: MRSSLAPGVWFFRAFSRDSWFRGLILLLTFLIYACYHMSRKPISIVKSRLHQNCSEQIKPINDTHSLNDTMWCSWAPFDKDNYKELLGGVDNAFLIAYAIGMFISGVFGERLPLRYYLSAGMLLSGLFTSLFGLGYFWNIHELWYFVVIQVCNGLVQTTGWPSVVTCVGNWFGKGKRGFIMGIWNSHTSVGNILGSLIAGIWVNGQWGLSFIVPGIITAVMGVITFLFLIEHPEDVDCAPPQHHGEPAENQDNPEDPGNSPCSIRESGLETVAKCSKGPCEEPAAISFFGALRIPGVVEFSLCLLFAKLVSYTFLYWLPLYIANVAHFSAKEAGDLSTLFDVGGIIGGIVAGLVSDYTNGRATTCCVMLILAAPMMFLYNYIGQDGIASSIVMLIICGGLVNGPYALITTAVSADLGTHKSLKGNAKALSTVTAIIDGTGSIGAALGPLLAGLISPTGWNNVFYMLISADVLACLLLCRLVYKEILAWKVSLSRGSGYKEI
What is the function of this protein?
Inorganic phosphate and glucose-6-phosphate antiporter.  May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction.  Independent of a lumenal glucose-6-phosphatase.  May not play a role in homeostatic regulation of blood glucose levels.
What are the official names of this protein?
Glucose-6-phosphate exchanger SLC37A2, Solute carrier family 37 member 2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SP15_STRGR
Sequence: MSREQRGPNEKLGTVLALAGISNAGLARRVNDLGAQRGLTLRYDKTSVARWVAKGMVPQGAAPHLIAAAIGAKLGRPVPLHEIGLADADPAPEVGLAFPRDVGEAVRSATELYRLDLAGRRGGGGIWQSLAGSFSVSAYATPASRWLITPADPSVARDPTAAQAAILGARGGGSGSPGGAGARGPGAAPDARGAHLLHPGGATPGAAGSVPLQPGPEAVADASPLRVGHSDVSKLREAAQDARRWDSKYGGGDWRSSMVPECLRVDAAPLLLGSYTDEVGRALFGASAELTRLAGWMAFDTGQQEAAQRYYIQALRLARAAADVPLGGYVLASMSLQATYRGFADEGVDLAQAAVERNRGLATARTMSFFRLVEARAHAKAGDAPAAGAALKGAESWLERSRAGDSDPPWLGFYGYDRFAADAAECYRDLKAPRQVRRFTEQALSRPTEEFVRSHGLRLVVSAVAELESGNLDAACAAGTRAVEVAGRISSARTTEYVRDLLHRLEPYGDEPRVAELRERARPLLVTPG
What is the function of this protein?
Might be a catalyst/regulator pair of proteins involved in the temporal controlled sporulation process.  The decrease in level of the smaller protein early in sporulation may relieve negative regulation of the activity of the larger protein.
What are the official names of this protein?
55.5 kDa and 49.5 kDa sporulation proteins, ORF1590 and ORF1422.
Protein: HISZ_BACC0
Sequence: MTKWKRANPNGTRDYLFEECTLIEEVEQKLRRTFLERGYEEIRTPTIEFYDVFAFQSRPIDEEKMYKFFDEKGRIIVLRPDMTIPLARVVGTQRCDTPLKVTYSGNVFRANESLAGKYNEIVQSGIEVIGIDNVRAEIECVISVIQSLQKLKVQSFTIEIGQVQLYKCIVKKLSIHEEEEKVLRTYIESKNYASLSNFIRDKKLDRCDETVKLLEKLPRLFGNLEVIEEAEKLASSNEMKMAITRVKEIYEAIEKLGYGSYISIDLGMIQHLDYYTGVIFKGYIYEIGEEIVSGGRYDELIGNFGEMLPAVGLAVQVNQIVKALQEQQEPYERKRIDIMIHYELNRLAEAERLRNLFQKDGKKVALSLFSNLNDTFQFARKNQIVTVVEAKSESLVEYVWKEKWVVQKEGETSCVTFKLR
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15E_METM5
Sequence: MSMYNYVKEAWKVPANSYVKELQWARMQDWRKEPSVIRIERPTRIDRARNLGYKAKQGIVVVRVSVRRGGLRKPRPKHSKKPATMGINKITMAKSIQRIAEERAAKKYPNMEVLNSYWVGQDGKQKWYEVILVDPCQPSIKNDKSYNWLCKGTHKGRVTRGLTSAGKKGRGLMYKGKGAEKARPSVRANGKKTK
What are the official names of this protein?
50S ribosomal protein L15e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
Protein: LOLB_SALEP
Sequence: MTLPDFRLIRLLPLASLVLTACTLPGHKGPGKSPDSPQWRQHQQEVRHLNQYQTRGAFAYISDDQKVYARFFWQQTGQDRYRLLLTNPLGSTELELNAQPGNVQLVDNKGQRYTADDAEEMIGKLTGMPIPLNSLRQWILGLPGDATDYKLDDQYRLSEVNYRQDGKNWKVVYGGYDSKTQPAMPANMELSDGSQRIKLKMDNWIVK
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RL331_LACLM
Sequence: MRVNITLEHKESGERLYLTQKNKRNTPDKLELKKYSKKLRKHVIFKEVK
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: USP7_PINMG
Sequence: MKYVALAFVLSLVILQISAQVGAAYIPGMGSIGSVGRAGAAAGASAGIGNQGRGAGLLRFFTLILENLMKNNQQAQPKQDNFGAQLQNLLKKKMILEMIN
What are the official names of this protein?
Uncharacterized shell protein 7, Nacre uncharacterized shell protein 3, NUSP3.
Protein: NIMI3_ARATH
Sequence: MDRDRKRVKMEKEDDEEEKMEKLYTVLKNAREMRKYVNSSMEKKRQEEEERARVRRFPSFQPEDFIFMNKAEANNIEKAANESSSASNEYDGSKEKQEGSETNVCLDLNLSL
What are the official names of this protein?
Protein NIM1-INTERACTING 3, Protein NIMIN-3.
What is the protein family that this protein belongs to?
Belongs to the NPR1-interactor family.
Protein: SECA_ACIF5
Sequence: MFGTIIRHVVGSRNDRLIKKARAIVAQVNALEDRFKAMDDATLAAQTAIFRERLARGEPLDALLPEAFAVVREVSRRVMGMRQYDVQIIGGFMLHEGKIAEMRTGEGKTLVATLPAYLNALQGKGVHVVTVNDYLASRDAEWVGKIHRFLGLSVGTIISDLSSEERRAAYAADITYGTNNEFGFDYLRDNMAFSPADRVQRGLHYAIIDEVDSILIDEARTPLIISGPTEENTDLYYRVDKLVGSFVVDEDYTVDEKARQVMLTEEGIEKAERLMAESGLLVDGDLYDLANVTLVHHLNQALRAHVIYRRETDYIVRDGEVCIVDEFTGRMMSGRRWSDGLHQAVEAKEGVAVQNENQTLASITFQNYFRMYEKLSGMTGTADTEAFELNQIYGLEVVIIPTHRPVCRTDFADLIYRTSQEKWKAIVEDIRGCQQRGQPVLVGTTSIEHNEFLSHLLKQARISHEVLNAKQHQREAEIIAQAGTPGAVTIATNMAGRGTDIVLGGNVGHQVDMVLANPDLEEEEKTRRIESLKSGWQGLHDAAIAAGGLHIIGTERHESRRIDNQLRGRSGRQGDPGTTRFYLSLDDPLMRIFGSDRLSGLMQKLGMKEGEAIEHPWVTKSIENAQRKVESRNFDIRKQLLEYDDVANEQRRIIYQQRNAFMDADDVSAEIRALRDDVLDAVLAATAPEGVMEERWDLPGLEAALDRIFGLQVPVGQWLEQDKGLTHAALRERIMEMVLSAYAAKESLMGSEMTRHFEKSILLQVLDSQWKDHLASMDHLREGIHLRGYAQKNPKQEYKRESLIMFNAMLDQLREEVVSTLSRLHVSPAPAEPLDWDAIARAAQPRHLQFSHPDFAAAAAPLVEDAGLALTGLGVIGEQEAGHSPAISDDKVGRNQPCPCGSGKKYKHCHGRLQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: RS5_METTP
Sequence: MIKGYEEEEWIPKTRLGRLVYEGQVTTFEEAVRSGLPIKEHQIIDLLLPGLEDEVLDITMVQRMTDSGRRVKFRTTVIVGNRDGYIGIGHGKDVQVGGAIKKGIENAKLNVVRINRGCGSWECGCGQAHTVPYKVSGSSGSVRIYLMPAPRGLGLAAGDVAKKVMEMAGIKDVWTRTEGSTRTTLNFAKATYNALLNTITVRS
What is the function of this protein?
With S4 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: HIMH_ASPJA
Sequence: MASLINQAAWQPKARTRSLQVGPGPTPSPNEHEIVIKVAYAAVNPTDWKMQDTPYFELEYPFIWGTDVAGTIVQLGSEVTQFKVGQRVIGHCDSLLTRKVTNAGFQLYTTVREILVAEIPDSLPLANAAVLPLSVSTAASALYVQLDLPFPSLSPKSTGKRIVIWGGSSSVGSSAIQLAVASGLEVVATASQANHDLVRSLGASQVFDHRAPSVIDQMASVLQPGDYVVDCIGSPDTQAKCGELVGRIGGGTLPVMLWPQGGLPQNVRAVFVNGLDPGMVNLDVGNAVWRKFIPEALAAGKFQAKPDPRIVPGGLEKVQEGIDMLRQGVSAQKIVIEISRSE
What is the function of this protein?
Trans-enoyl reductase; part of the him gene cluster that mediates the biosynthesis of himeic acid A, a ubiquitin-activating enzyme (E1) inhibitor (PubMed:29314577).  First, himA, together with the trans-enoyl reductase himH, catalyzes the formation of apolyketide chain, which is then condensed with leucine by the NRPS activity of himA.  Dieckmann cyclization and release from himA gives a tetramic acid intermediate as the product of himA PKS-NRPS (PubMed:29314577).  HimG then catalyzes alpha-oxidation of the tetramic acid ring, with a subsequent rearrangement to yield apyrone intermediate (Probable).  Two terminal methyl groups of polyketide and amide side chains are oxidized to carboxylic acids by himC cytochrome P450 monooxygenase to form himeic acid A (Probable).  Himeic acid A is further converted to himeic acid B and C during culture growth.  No gene responsible for pyrone to pyridone conversion was found in the him gene cluster and himeic acid A is non-enzymatically converted to himeic acid C by the incorporation of an ammonium nitrogen atom in a pH5 buffer, and to himeic acid B at a conversion ratio of 50% during incubation in MeOH for 5 days (PubMed:29486950).
What are the official names of this protein?
Trans-enoyl reductase himH, Himeic acid A biosynthesis cluster protein H.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: RL35_SINFN
Sequence: MPKMKTKSSAKKRFKVTATGKVRAAAAGKRHGMIKRTNKFIRDARGTMVLAEPDGKKVVKNYLPNGL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: SUFE_ECOL6
Sequence: MALLPDKEKLLRNFLRCANWEEKYLYIIELGQRLPELRDEDKSPQNSIQGCQSQVWIVMRQNAQGIIELQGDSDAAIVKGLIAVVFILYDQMTPQDIVNFDVRPWFEKMALTQHLTPSRSQGLEAMIRAIRAKAAALS
What is the function of this protein?
Participates in cysteine desulfuration mediated by SufS.  Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.
What are the official names of this protein?
Cysteine desulfuration protein SufE.
What is the protein family that this protein belongs to?
Belongs to the SufE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BR2C_SYLGU
Sequence: MFTMKKSLLLLFFLGMISLSLCEQERGADEDEGEVEEQIKRSIWEGIKNAGKGFLVSILDKVRCKVAGGCNP
What is the function of this protein?
Antimicrobial peptide.  Active against the Gram-positive bacteria S. aureus FDA209P (MIC=9. 8 ug/ml) and B. subtilis ATCC 6633 (MIC>64 ug/ml), and the Gram-negative bacteria E. coli O111 (MIC=19. 6 ug/ml) and E. coli ATCC 25922 (MIC=9. 8 ug/ml).  Not active against the fungus C. albicans.
What are the official names of this protein?
Brevinin-2GHc, AMP-4.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: DPO4_CALS4
Sequence: MKRKIIHVDMDAFFASIEQQDNPEYRGKPVIVGGLSGRGVVSTCSYEARKYGIHSAMPMYMAKKLCPQGIFLPVRRKRYEEVSEQIFRILYDITPFVEPVSIDEAYLDVTHVDKNPEDIALEIKKRVKDATGLTVSVGISYNKFLAKLASDWNKPDGLMVITEDMVPEILKPLPVTKVHGIGEKSAEKLRSIGIETVEDLLKLPQENLIELFGKTGVEIYNRIRGIDERPVETMREIKSIGKEKTLEKDTKNKELLIQHLKEFSEIVSEELIKERLYCRTVTVKIKTADFAVHTKSKTVDKYIRFSEDIYEVAKGILEEWKLEQYVRLIGLSVSNLSPVKYEQLSFLDKRLVKVIKAGNLAEEINKRIGKKIIKKGSELLKDNK
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBFL_ECOLI
Sequence: MELKKLMEHISIIPDYRQAWKVEHKLSGILLLTIFAVISGAESWEDIEDFGETHLDFLKQYGDFENGIPVHDTIARVVSCISPAKFHECFINWMRDCHSSNDKDVIAIDGKTLRHSYDKSRRRGAIHVISAFSTMHSLVIGQIKTDKKSNEITAIPELLNMLDIKGKIITTDAMGCQKDIAEKIQKQGGDYLFAVKGNQGRLNKAFEEKFPLKELNNPEHDSYAMSEKSHGREEIRLHIVCDVPDELIDFTFEWKGLKKLCVAVSFRSIIAEQKKEPEMTVRYYISSADLTAEKFATAIRNHWHVENKLHWRLDVVMNEDDCKIRRGNAAELFSGIRHIAINILTNDKVFKAGLRRKMRKAAMDRNYLASVLAGSGLS
What are the official names of this protein?
Putative protein YbfL, H repeat-associated protein in rhsC-phrB intergenic region, ORF-H2.
What is the protein family that this protein belongs to?
Belongs to the transposase 11 family.
Protein: YL006_YEAST
Sequence: MTQLSQSNVERVALVYISVYFFSCISLIVYFFTFCLSVSIPKNRQHPIKIIYNNKCPS
What are the official names of this protein?
Uncharacterized protein YLL006W-A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MGSA_SERP5
Sequence: MEFTTRTIAARKHIALVAHDHRKQALLAWVEDNKSVLEQHQLYATGTTGNLIQQASGIPVNSMLSGPMGGDQQVGALIAEGKIDMLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNRSTADFLIDSSLFKSEVEIAIPDYQRYLQDRLK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.