PharMolix/UniProtQA huggingface dataset:
Protein: SPB4_AJECN
Sequence: MATSASRIAPTTPQSSHSRAWDALTPPLSEWILDAISAMGFSRMTPVQASTIPLFMAHKDVVVEAVTGSGKTLAFLIPVVERLLRLESPIKKHHIGAILISPTRELATQIYNVLLSLLAFHGPSAARLQRTENNSGEVDESNPASSYPPSTLKIVPQLLLGGTTTPTQDLSAFLKQSPNVLVSTPGRLLELLSSPHAHCSQSSFEVLVLDEADRLLDLGFKEDLQKILQRLPKQRRTGLFSASVSEAVDQIIRVGLRNPVKIAVKVKGAGLEDKRTPASLQMTYLLTPPTHKLPAVKYIVSTLSPTPQRSILYFSTCAAVDYYQHILPCILPDRFTTIPLHGKHPPQVRQKNFTRFVNSVTSSILLTTDVAARGLDIPAVDLVIQIDPPTDPKAFLHRCGRAGRAGRRGLSVIFLHPGREEDYIAFLNVRKTPVTEFQSTSTSTPSQLYSSSHFSASSPKNPQTFHPIQITTADATSTTEKIRALVLRDRAIHDKAQRAFVSWLRSYSKHQASSIFRVADLDWEELGRAWGLLRLPTMPELKGFTGDRNLGVSGVDWDNYAYKDRQREKHRRMEMEGRSSSNVNNNGDATGSDKGPLKRPATSESIPWSQNLERKSEKERRRERKKIRRYHEQWKKMTEEEKERVRETEQMVNAVRKAVQEQDQTVTREEEFEGFD
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits.  Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA.  Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5. 8S rRNAs through the processing of pre-rRNAs at sites C1 and C2.
What are the official names of this protein?
ATP-dependent rRNA helicase SPB4.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RF1_STAAM
Sequence: MFDQLDIVEERYEQLNELLSDPDVVNDSDKLRKYSKEQADLQKTVDVYRNYKAKKEELADIEEMLSETDDKEEVEMLKEESNGIKAELPNLEEELKILLIPKDPNDDKDVIVEIRAAAGGDEAAIFAGDLMRMYSKYAESQGFKTEIVEASESDHGGYKEISFSVSGNGAYSKLKFENGAHRVQRVPETESGGRIHTSTATVAVLPEVEDVEIEIRNEDLKIDTYRSSGAGGQHVNTTDSAVRITHLPTGVIATSSEKSQIQNREKAMKVLKARLYDMKVQEEQQKYASQRKSAVGTGDRSERIRTYNYPQSRVTDHRIGLTLQKLGQIMEGHLEEIIDALTLSEQTDKLKELNNGEL
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CALI_PENDC
Sequence: MALDRYAALHVSTPQGRGDGRPTADQVLRDQDPLGSHWSDKVILITGGTAGLGAESARVLHKTGAKIFIMGRDIAKGEKVAADISASNPDYPPIEVIQMDQSRLESVREGAVEFLKRSGGKLNVLMANAGIVASPVKETQDGFEAVFAINYLSTFLLVQLLAPALVASTTPEYNSRLVVVSSAGHRASNIDPDKYNLVGEGYDPSKAYARSKTASILMANEFERRYGDRGVHALSLNPGIIMDTEISRGLPGTSASRREQYYKMEPLLAQYEKDVMQGAATQVWATVAKELEGKGGLYLDDVQVAREATHEGQFCRPGWKPWIWNEDNAVRLWKDSLNMVGLESEN
What is the function of this protein?
Oxidoreductase; part of the gene cluster that mediates the biosynthesis of calbistrin A and related compounds.  Calbistrin A is a secondary metabolite with an interesting structure that was recently found to have bioactivity against leukemia cells.  It consists of two polyketides linked by an ester bond: a bicyclic decalin containing polyketide and a linear 12 carbon dioic acid structure (PubMed:30598828).  The polyketide synthase calA is probably responsible for forming the decalin moiety.  Because calA lacks a designated enoylreductase (ER) domain, the required activity is provided by the trans-enoyl reductase calK (PubMed:30598828).  Following release from the PKS, calF then probably catalyzes the oxidation and the subsequent Diels Alder cycloisomerization that lead to the formation of the decalin moiety (Probable).  The decalin polyketide backbone includes two C-methyl groups, at C7 and C11 in backbone, of which the C7 position is probably methylated by the methyltransferase domain of calA.  A candidate for adding the methyl group at C11, if not done by CalA, is the cluster methyltransferase calH (Probable).  Several additional tailoring enzymes within the cluster could be involved in the modification of the decalin polyketide product.  Those include the 3 cytochrome P450 monooxygenases CalE, CalG and CalL, of which one might be responsible for the introduction of the extra hydroxyl group attached to the backbone of the decalin moiety, at position C9 in the backbone, that allows for attachment of the linear moiety (Probable).  One tailoring enzyme activity that is expected to be involved in biosynthesis of calbistrin is an acyltransferase for connecting the two polyketide synthase products, and which could be performed by the cluster acyltransferase calJ (Probable).  The enzyme responsible for the biosynthesis of the linear moiety, probably a second PKS, has not been identified yet (Probable).
What are the official names of this protein?
Oxidoreductase calI, Calbistrin biosynthesis cluster protein I.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: NAP1C_ARATH
Sequence: MSNDKDSFNVSDLTSALKDEDRAGLVNALKNKLQNLAGQHSDVLENLTPKIRRRVEVLREIQGKHDEIETKFREERAALEAKYQKLYQPLYNKRYEIVNGATEVEGAPEDAKMDQGDEKTAEEKGVPSFWLTALKNNDVISEEITERDEGALIYLKDIKWCKIEEPKGFKLEFFFDQNPYFKNTLLTKAYHMIDEDEPLLEKAIGTEIDWYPGKCLTQKILKKKPKKGAKNAKPITKTEDCESFFNFFNPPQVPDDDEDIDEERAEELQNLMEQDYDIGSTIREKIIPHAVSWFTGEAIEGEEFEIDNDDEDDIDEDEDEDEEDEDEDEEEDDEDEEEEVSKTKKKPSVLHKKGGRPQVTDDQQGERPPECKQQ
What is the function of this protein?
May modulate chromatin structure by regulation of nucleosome assembly/disassembly (By similarity).  May function in nucleotide excision repair (NER).  Involved in somatic homologous recombination.  Could be involved in response to abscisic acid (ABA) and to salt stress.
What are the official names of this protein?
Nucleosome assembly protein 1;3, AtNAP1;3, Nucleosome/chromatin assembly factor group A3.
What is the protein family that this protein belongs to?
Belongs to the nucleosome assembly protein (NAP) family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly located in cytoplasm.
Protein: QUEC_BACMK
Sequence: MKKEKAVVVFSGGQDSTTCLFWAIQQFEEVEAVTFNYNQRHKLEIDCAVEIAKELGIKHTILDMSLLNQLAPNALTRTDMEITHEEGELPSTFVDGRNLLFLSFAAVLAKQVGARHIVTGVCETDFSGYPDCRDVFVKSLNVTLNLSMDYPFVIHTPLMWIDKAETWKLSDELGAFEFVREKTLTCYNGIIGDGCGECPACQLRKAGLDTYLQEREGASN
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: SLX1_PHANO
Sequence: MSEALKIESRPIPAFYCCYLLRSKNRKSYYIGSTPNPARRLGQHNGSSKGGAKRTSMQGKRPWEMTCIVTGFPSKFAALQFEWAWQNTHATRHIDKDVRDARAEELQKGKKKATSPGRRRKRPPMSLEARLKNLHHLLSVDSFCRWPLNLRFFAPDVFVQWERHTTKMTTTLRKSITIQLTPAEIPKLASDVSTELQTHFIPEVIRAIPVAYEDCKQYIEKSRRVLEDDQRLGCGVCKNPADMSSSLILVCPIEACQTVSHLSCLSNKFLTEGGELETLVPLEGTCPGCRSCIKWATMIKELSLRTNGEEELKLLFKPKRKRKSDNPAESDAADGQALEQEDEELDETWMEDMSQDEEPSPVKKSR
What is the function of this protein?
Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit SLX1.
What is the protein family that this protein belongs to?
Belongs to the SLX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TPIS_YERP3
Sequence: MRHPLVMGNWKLNGSTHMVNELIAGLRKELSTVDGCGVAIAPPAIYLNQAKHELAGSRIALGAQNVDVNLSGAFTGETSAEMLKDIGAQYIIIGHSERRTYHQESDELIAKKFGVLKEIGLIPVLCIGESEAENEAGQTEAVCAKQLDAVLNTLGVKAFEGAVIAYEPIWAIGTGKSATPAQAQAVHKFIRDHIAKQDAAVAAQVIIQYGGSVNDKNAAELFTQPDIDGALVGGASLKADAFAVIVKAAAKAKKA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_BUCBP
Sequence: MKSKTKTRRKAREYAVQALYSWQISKNDIYDVINHFKKNKTINEIDQIYFYELIIGITKNLKYLDELMRPYLSRTIQELGQIEKAILRISFFELDKRYDIPFKVTINESIELAKLFGAKDSHKFINGVLDKASLKLRKNNSNKN
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: PLD3B_RAT
Sequence: MKIWTSEHVFDHPWETVTTAAMQKYPNPMNPSVVGVDVLDRHVDPSGKLHSHRLLSTEWGLPSIVKSLIGAARTKTYVQEHSVVDPIRRTMELKSTNISFTNMVSVDERLTYKPHPQDPEKTVLTQEALITVKGVSLSSYLEGLMASTISSNANKGREAMEWVIHKLNAEIEELAASARGSIRTPMAAAAALVDK
What are the official names of this protein?
PRELI domain containing protein 3B, Protein slowmo homolog 2.
What is the protein family that this protein belongs to?
Belongs to the slowmo family.
Protein: TBX15_HUMAN
Sequence: MSERRRSAVALSSRAHAFSVEALIGSNKKRKLRDWEEKGLDLSMEALSPAGPLGDTEDAAAHGLEPHPDSEQSTGSDSEVLTERTSCSFSTHTDLASGAAGPVPAAMSSMEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQGGSTGTSPTTSSTGTPSPSASSHLLSPSCSPPTFHLAPNTFNVGCRESQLCNLNLSDYPPCARSNMAALQSYPGLSDSGYNRLQSGTTSATQPSETFMPQRTPSLISGIPTPPSLPGNSKMEAYGGQLGSFPTSQFQYVMQAGNAASSSSSPHMFGGSHMQQSSYNAFSLHNPYNLYGYNFPTSPRLAASPEKLSASQSTLLCSSPSNGAFGERQYLPSGMEHSMHMISPSPNNQQATNTCDGRQYGAVPGSSSQMSVHMV
What is the function of this protein?
Probable transcriptional regulator involved in the development of the skeleton of the limb, vertebral column and head.  Acts by controlling the number of mesenchymal precursor cells and chondrocytes (By similarity).
What are the official names of this protein?
T-box transcription factor TBX15, T-box protein 15, T-box transcription factor TBX14, T-box protein 14.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y5G6_ENCCU
Sequence: MSNTHVPEPHETNEQRHPTNQSRSKVTYNGLASVISVALPIAMYFIFDKDRFKEDPLLRFATILLPFSYSATQYLFLLYANWKSNYKPEDTLHKALYYSFNALLIAFATISILSIVALPIDGWGSRNDIVIHSVILPFFVVWSAYLTFTINCLIMKTIRLTDVNFCMLIALMMMIRIIVEFKSSNREYRYYRQMPTPMFRDTFLPTIKRMVSILTTMLVLATFMYAFIAWKCLIFLRNM
What are the official names of this protein?
UPF0328 protein ECU05_1660/ECU11_0070.
What is the protein family that this protein belongs to?
Belongs to the UPF0328 family.
Protein: RBSD_VIBC3
Sequence: MKKSTLLNSELSYLVATLGHTDEITICDAGLPIPDEVTRIDLALTHGVPSFLETVRVILSESQIESVIVAQEFAQVSPVLHEALYRELKAEEQLCGKPIAIQYISHEAFKQRTLQSRAVVRTGECTPYANVIFQAGVVF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPRS_BACSU
Sequence: MSNQYGDKNLKIFSLNSNPELAKEIADIVGVQLGKCSVTRFSDGEVQINIEESIRGCDCYIIQSTSDPVNEHIMELLIMVDALKRASAKTINIVIPYYGYARQDRKARSREPITAKLFANLLETAGATRVIALDLHAPQIQGFFDIPIDHLMGVPILGEYFEGKNLEDIVIVSPDHGGVTRARKLADRLKAPIAIIDKRRPRPNVAEVMNIVGNIEGKTAILIDDIIDTAGTITLAANALVENGAKEVYACCTHPVLSGPAVERINNSTIKELVVTNSIKLPEEKKIERFKQLSVGPLLAEAIIRVHEQQSVSYLFS
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PPRibP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GC_GAHVR
Sequence: MLTPRVLRALGWTGLFFLLLSPSNVLGASLSRDLETPPFLSFDPSNISINGAPLTEVPHAPSTESVSTNSESTNEHTITETTGKNAYIHNNASTDKQNANDTHKTPNILCDTEEVFVFLNETGRFVCTLKVDPPSDSEWSNFVLDLIFNPIEYHANEKNVEAARIAGLYGVPGSDYAYPRQSELISSIRRDPQGTFWTSPSPHGNKYFIWINKTTNTMGVEIRNVDYADNGYMQVIMRDHFNRPLIDKHIYIRVCQRPASVDVLAPPVLSGENYKASCIVRHFYPPGSVYVSWRQNGNIATPRKDRDGSFWWFESGRGATLVSTITLGNSGIDFPPKISCLVAWKQGDMISTTNATAIPTVYHHPRLSLAFKDGYAICTIECVPSEITVRWLVHDEAQPNTTYNTVVTGLCRTIDRHRNLLSRIPVWDNWTKTKYTCRLIGYPFDEDKFQDSEYYDATPSARGTPMVITVTAVLGLAVILGMGIIMTALCLYNSTRKNIRL
What is the function of this protein?
May play an immunoevasive role in the pathogenesis of Marek's disease.  It is a candidate for causing the early-stage immunosuppression that occurs after MDHV infection.
What are the official names of this protein?
Envelope glycoprotein C homolog, A antigen, Glycoprotein A, GA, Secretory glycoprotein GP57-65.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein C family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane; Single-pass membrane protein. Note=Predominantly secreted. Secreted, but a small amount of mature GP57-65 is anchored in the plasma membrane or held by other interactions.
Protein: MIAB_ACIC1
Sequence: MTLLDSDSRQSAEVLPAAGPAPDRPRTYQVRTFGCQMNMHDSERIAGLLEAAGYVRAADDEPADVVVFNTCAVRENADNRLYGNLGLLLPVKKAKPDMQIAVGGCLAQKDKGDIVRRAPWVDVVFGTHNIEALPVLLERARIAREAQVEIREALEVFPSTLPSRRESVYAAWVAISVGCNNTCTFCIVPSLRGRERDRRPGDILREIQTLVADGVLEVTLLGQNVNSYGVDFGDRQAFAKLLRACGTIDGLERVRFTSPHPRDFTDDVIAAMAETPNVMPQLHMPLQSGSDAVLRRMRRSYRKEKYLDIISRVRSAIPDAAITTDIIVGFPGETEDDFAETLDVVRKARFAGAFTFQYSKRPGTPAAEMPDQVPPDVVADRFARLVALVEQIALEENQAQVGRVVEVLVAEGEGRKDAETHRMSGRAPDNRLVHFRATDARPGDVVTVAVTQAAPHCLIADQVLGVRRTRAGDAWEARRSVRPSGVLLGMPALRPRT
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_LISW6
Sequence: MHLESIVLRNFRNYENLELEFSPSVNVFLGENAQGKTNLLEAVLMLALAKSHRTTNDKDFIMWEKEEAKMEGRVVKRGQTVPLELAITQKGKRAKVNHLEQKKLSQYVGNLNVVIFAPEDLSLVKGAPGIRRRFLNMEIGQMQPIYLHNLSEYQRILQQRNQYLKMLQMKRKVDPMLLDILTEQFADVAINLTKRRADFIQKLEAYAAPIHHQISRGLETLKIEYKASVTLNGDDPDTWKADLLQKMESIKQREIDRGVTLVGPHRDDSLFYINGQNVQDFGSQGQQRTTALSVKLAEIDLIHEETGEYPVLLLDDVLSELDDYRQSHLLGAIEGKVQTFVTTTSTSGIDHDTLKQATTFYVEKGTVKKS
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURI_SACEN
Sequence: MTHAPIGIFDSGVGGLTVARAIMDQLPGEALRYVGDTANAPYGPRPLADIRARTLAITDSLVAEGVKMLVIACNSASAACLRDARERYDVPVVEVVLPAVRRAVATTRNGRVGVIGTQATITSRAYDDAFTAAPGVTLSTAACPRFADFVERGITSGRQVLGLAQAYLDPLQQADVDTLVLGCTHYPLLTGVLQLAMGDHVTLVSSAEETAKDVLRVLTEHDLLAEADGEPAHEFRATGSGESFAKLARRFLGPSLAADAIDPLAVSSSSA
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: GSPK_DICCH
Sequence: MSRRQRGVALLIVMLMLSLMVTIAASITERSGKAWQRTSNLLNRTQARWYALGAEALISNVLQRDAQASPESTFIGQPWSKVDHQMMADGTEIRAQALDGQACLNLNALSPARNVTPNNASGNNTSGNNNAANGSSGNGNSPQPPKVGTSEQVPYAAQVFRQLMIVLGEDPKQAERITDALRDWLDEDSEPLMNGAEDDSYVNFHPGNQRMTDVTELRAVMGMDAALYRRLLPYVCVLPVDKLAINVNTLMPGSAPLLSALFMGDISLDMAERILQQRPPQGWRNLNDFMGMSALPESGKNGARQVLVIKSDWFFADIQIRVDDSEFYQRSLFHRGKQIEVVQRQYGGYRTVNP
What is the function of this protein?
Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.  Plays a role in pseudopilus assembly and seems to control its length.  Interacts with the pseudopilus tip complex that is critical for the recognition and binding of secretion substrates.
What are the official names of this protein?
Type II secretion system protein K, T2SS protein K, General secretion pathway protein K, Pectic enzymes secretion protein OutK.
What is the protein family that this protein belongs to?
Belongs to the GSP K family.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: DXR_CAMJE
Sequence: MILFGSTGSIGVNALKLAALKNIPISALACGDNIALLNEQIARFKPKFVSIKDSKNKHLVKHDRVFIGQEGLEQILTECQDKLLLNAIVGFAGLKSTLKAKELGKNIALANKESLVVAGSFLKGAKFLPVDSEHAALKFLLEGKKNIAKLYITASGGAFYRYKIKDLNQVSVKDALKHPNWNMGAKITIDSATMANKLFEIIEAYHLYDFKEIDALIEPRSLVHAMCEFKNGASTAYFSKADMKLAISDAIFEKQDTPILEAVDFSKMPALKFHPISTKKYPIFKLKNTFLKEPNLGVIINAANEVGVYNFLENKSGFLDIAKCIFKALDHFGVPKISSIEEVFEYDFKTREYLRS
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: ZAPB_HAEDU
Sequence: MSLSIIDQLEEKIKQAVETIQLLQLEVEELKEKNNNLTQERDGLRQEHEQLKVEQQNFQERLRSLLGQIDNV
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid- cell, in a FtsZ-like pattern.
Protein: NAP1_CANAL
Sequence: MTEQPINTKKKNGDISKAPTPQNTPASVTNSYMRSKPPTVSTIQESNNEDGTGAAAAAGGLANNPVLLSMIQGKLGDLVGKQSGYIDNLSKPVKNRVYGLKSLQLNQMKLEAQFQKELLELEKKFFAKYQPLYVKRKQIINGELEPTVEEIEEGQQLEEEEKGIDKEDGEEEEEEEEDDEEEDEQGIPGFWLTALENLSTVSETITDRDSEVLSNLIDIRMEYLSTPGFQLIFEFKPNDFFENQTLTKTYHYQAELGYSGDFVYDHADGCEIRWKSKENNVTITIERRKQRNKTTKQTRTIEKLTPTESFFNFFDPPKPPKIKSEDDDNDDKLQDKEEANDDDEGEEGDEEDEELEARLELDYQLGEEIKDRLIPRAIDWFTGDAVDFDYPELEGEGDEDEYSDEDGEGDSDDDDDDDDEAAGSQKQPPPECKQQ
What is the function of this protein?
Acidic protein, which assembles histones into an octamer (By similarity).  Involved in the regulation of the localization and the function of the septins during mitosis.
What are the official names of this protein?
Nucleosome assembly protein 1.
What is the protein family that this protein belongs to?
Belongs to the nucleosome assembly protein (NAP) family.
What are the subcellular locations of this protein?
Bud neck. Bud tip. Note=Has not been detected in the nucleus.
Protein: RL15_MYCUA
Sequence: MTIKLHDLRPAPGSKTPRTRVGRGEGSKGKTAGRGTKGTKARKQVPTTFEGGQMPIHMRLPKLKGFRNRFRTEYEIVNVGDIARLFPEGGTVGVDELVAKGAVRKNSLVKVLGDGKLTVKVDITAHKFSGSAREQITAAGGSVTEL
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: OR1B1_HUMAN
Sequence: MMSFAPNASHSPVFLLLGFSRANISYTLLFFLFLAIYLTTILGNVTLVLLISWDSRLHSPMYYLLRGLSVIDMGLSTVTLPQLLAHLVSHYPTIPAARCLAQFFFFYAFGVTDTLVIAVMALDRYVAICDPLHYALVMNHQRCACLLALSWVVSILHTMLRVGLVLPLCWTGDAGGNVNLPHFFCDHRPLLRASCSDIHSNELAIFFEGGFLMLGPCALIVLSYVRIGAAILRLPSAAGRRRAVSTCGSHLTMVGFLYGTIICVYFQPPFQNSQYQDMVASVMYTAITPLANPFVYSLHNKDVKGALCRLLEWVKVDP
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 1B1, Olfactory receptor 9-B, OR9-B, Olfactory receptor OR9-26.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1078_AQUAE
Sequence: MYLENCIVILTSTTPPWWAIPPAWSLGAEIQAYFLLPILLTYKMLGLSVFWISYIIYSLANLNIIHSDYFGYRLIPGVIFMFLSGAYLQKIVSGKASRLEMLSLIIIYIISLFWLVFFIIIKGKYGAYTRETLLGLLVGIPLVYTLLKIRRKFYFNDLFGKLSYGIFLSHFLSFWILEFVNLTQNIISMIFLSLIISASVSYLIITLIENKVEKIRYNLTR
What are the official names of this protein?
Uncharacterized protein aq_1078.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IBPB_ECOSE
Sequence: MRNFDLSPLMRQWIGFDKLANALQNAGESQSFPPYNIEKSDDNHYRITLALAGFRQEDLEIQLEGTRLSVKGTPEQPKEEKKWLHQGLMNQPFSLSFTLAENMEVSGATFVNGLLHIDLIRNEPEPIAAQRIAISERPALNS
What is the function of this protein?
Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpB, 16 kDa heat shock protein B.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF3_BART1
Sequence: MTPTQKDGPRSNQDIRVPHVQLINDEGQHQGVVSIQEALAMAAEAGLDLVEIVPNAEPPVCKIIDLGKLKYQTQKKAAETRKKQKVIEIKEIKVRPNVDVHDYGVKLKAIHRFIDHGDKVKITLRFRGREMAHQDLGLKLLQRVKEDTSEIAKIELEPKLEGRQMMMVIAPK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_GEOSM
Sequence: MAITKEEVISFIENMSVLELANLVKELEEKFGVSAAAPVAVAAAGPAAGPAEAAEEKTEFDVILKSAGANKIAVIKVVRALTSLGLKEAKDLVDGAPQPVKTGISKEEAADAQKQLVEAGAEVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.