PharMolix/UniProtQA huggingface dataset:
Protein: GATF_DEBHA
Sequence: MSRMLNQIPRLITRSFRTSSVGYKATLGPILENKSQIQDLVNKSEWNIVDIIKFSEDEVRNIKIDSRVITKMLRASGLKDSLSEDQKKSLIRGLKLQMIFIKYLYEGDEAEFHKIEESNDDVFRLILSDHKAPKPITLKSLLSSIENLENEVDAEKGEIKSSLDISKLNGNNPTYFTVRSNKE
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).  Required for proper protein synthesis within the mitochondrion.
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit F, mitochondrial, Glu-AdT subunit F.
What is the protein family that this protein belongs to?
Belongs to the GatF family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: EIF3I_CULQU
Sequence: MKPLMLQGHERAITQIKYNREGDLIFSTAKDHKPSVWFSLNGERLGTYNGHQGAVWCVDVDWTTTRLITGAGDMSTKLWDVETGSVLGTIPCNSAARTANFSFSGNQASYSTDKAMGHNSELFIIDVRNVDSSISSQSPVLKLTMNQSIQTKITSMLWGALDETVITGHENGSIRIWDLRTAKELNSVNDHTGVINDMQLSADGTMLVSASKDTTAKLFDSESLMCLKTYKTERPVNSAAISPIHEHVVLGGGQEAMEVTTTSTKSGKFDSRLFHLVYEEEFARVKGHFGPINSLAFHPDGKSYATGGEDGFVRVQVFDASYYEFVFE
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit I, eIF3i.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit I family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y566_BACCQ
Sequence: MSIKYSNKINKIRTFALSLVFIGLFIAYLGVFFRENIIIMTTFMMVGFLAVIASTVVYFWIGMLSTKTVQIICPSCDKPTKMLGRVDACMHCNQPLTMDRNLEGKEFDEKYNKKSYKS
What are the official names of this protein?
UPF0295 protein BCQ_0566.
What is the protein family that this protein belongs to?
Belongs to the UPF0295 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUG1_YEAST
Sequence: MRVRKRQSRRTSTKLKEGIKKKASAHRKKEKKMAKKDVTWRSRSKKDPGIPSNFPYKAKILEEIEAKKMKDLEERELAKQQRLEARKAAKEQGVDAMDEDMIEDDENGLAALVESAQQAAAEYEGTPSNDADVRDDELDVIDYNIDFYGEDVEGESELEKSRKAYDKIFKSVIDASDVILYVLDARDPESTRSRKVEEAVLQSQGKRLILILNKVDLIPPHVLEQWLNYLKSSFPTIPLRASSGAVNGTSFNRKLSQTTTASALLESLKTYSNNSNLKRSIVVGVIGYPNVGKSSVINALLARRGGQSKACPVGNEAGVTTSLREIKIDNKLKILDSPGICFPSENKKRSKVEHEAELALLNALPAKHIVDPYPAVLMLVKRLAKSDEMTESFKKLYEIPPIPANDADTFTKHFLIHVARKRGRLGKGGIPNLASAGLSVLNDWRDGKILGWVLPNTSAAASQQDKQNLSTINTGTKQAPIAANESTIVSEWSKEFDLDGLFSSLDKAIDASKDQDTMME
What is the function of this protein?
GTPase required for 60S ribosomal subunit export to the cytoplasm.
What are the official names of this protein?
Nuclear GTP-binding protein NUG1, Nuclear GTPase 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RIBBA_GEOSW
Sequence: MFDMIEEAIYELMQGKVIIVCDDEDRENEGDFVALAEKATPEVINFMIKYGRGLVCVPITEELADKLDLAPMVNHNTDSHGTAFTVSIDYKSTTTGISAYERSMTIQALLDPNAKASDFKRPGHVFPLVAKKGGVLRRAGHTEAAVDLARLCGAKPAGVICEIIKEDGTMARVSDLRKIADEFDLKMITIKDLIEYRRRKEKLVKREVEVMLPTEFGKFKAIGYTNIVDGKEHVALVKGEIIPDEPTLVRVHSECLTGDVFGSCRCDCGPQLHAALRQIEEEGRGVLLYMRQEGRGIGLINKLRAYKLQEQGYDTVEANERLGFPADLRDYGIGAQILKDLGVTKMRLLTNNPRKITGLKGHGLEVVERVPLQMPANKENEKYLRTKYEKLGHMLHF
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: WECB_METMP
Sequence: MYKIGIILGTRPEIIKMSPVIRELTTKKFFLIHTNQHYSENMDKIFFEELNLKKPDYNLNIGSGSHGDQTGRMLMEIEKVLLKEKPDFVLVQGDTNTVLAGALAASKLGIKIGHIEAGLRSFDRKMPEETNRVLTDHISEFLFAPTKTAANNILKEGISDEKIHIVGNTIVDATIQNLKIAEKNEKVCKFISKITKNEKYFLLTLHRAENTDNFEILSKLVTSINNISKKYEKNIIFPIHPRTHKKLNEFGLINKLENNHLIKIIEPVGYLEFLGLEKNAELIITDSGGLQEEACILNVPCVTLRENTERPETLDVNSNILAGSDPENILNCVEKMLKSNRHWNNPFGDGNSGKIIVNIVFGEKKP
What is the function of this protein?
Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.
What are the official names of this protein?
UDP-N-acetylglucosamine 2-epimerase, UDP-GlcNAc-2-epimerase.
What is the protein family that this protein belongs to?
Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_CAMFF
Sequence: MANIRIHEIAKELGYSNKEILEKAKELGFKVTTSSSAVTPEDAAQLYDYVQSGKKPESPEKKDIKQNTQKEAPETQTQQKPIEQEVETKQNIDSTPIKVEPKQESLASSTLSKRRGLVIVKKKKVEVQPIQKQQSEPINKGLEAIFGSSDENLKKKKKEKKPIIATKKENSAKIDLLSAISFSDDISIDDEDVVVLPDLTVKPIEIERQNTVKKQINVYKTSQNNSFSFEGGIQRNSRKKHKKVVKDKDNEDISSVDIPKEIRLYEFADKIKKSSSEVIAKLFILGKMTTKNDFLEEDEIEILGAEFGIEVNIVDTKEDFDYVKAYEDEILEDNSVSRAPVVTIMGHVDHGKTSLLDYIRNSRVASGEAGGITQHVGAYMVEKSGKNITFIDTPGHEAFTAMRARGASVTDIVIIVVAADDGVKPQTKEAINHAKAAGVPIIIAINKMDKESANPDLVKTGLAELDILPTEWGGGYEFVPISAKTGIGIEDLLEIVLLQAELLELKANPDREAKATIIESSLQKGRGPVATAIVENGTLRVGDTIVAGVAYGKVRALQDDKGNSLKSIKPGECGVIIGLSEVPDAGETLISVKTDKEAREYAQKKYDYLRQKELSKSTKVTIDELSAKIAEGELKSLPVIIKADVQGSLEAIKASLEKLKNDEIKVDIIHSGVGGISQSDITLASASSNCVILGFNIRPTGDVKEKAKERSVEIKTYNVIYNLIDDVKALLSGLMSPIISEEELGQAVIRQVINVPKIGQIAGCMVTDGSINRGAKIRVIRDGVVVFEGNVSSLKRFKDDVKEVAKGYECGVGIEGYNDMREGDYIESYKEVESKVEL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH4_BURMA
Sequence: MNPEFAMPDVQSTVDTRQMPIQRVGVRAVRHPLTVRTAEGETQATVGTWNLDVHLPADQKGTHMSRFVALLEERGGPLTADAFRTMLATMLEKLEARAGRIEVSFPYFVNKTAPVSGVRSLLDYEVTLTGDVRDGLTRVFAKVLVPVTSLCPCSKKISQYGAHNQRSHVTIDAELAADVPVEDLIRIAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRDVARRLDADERIVAYVLEAENFESIHNHSAYALIERDKRRGA
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: DMP7_ARATH
Sequence: MEETKQSLIASLPSAPRKPKSKVERVVRKTFKGTAHLSNLLPTGSVMSFQIMCPVLTHQGQCPTITSRWLTCFLVSLCAISCFLFSFTDSIRDPNGKVRYGLATWSGLLVMDGSITLTEEEKEKYKLKILDFIHAIMSMLVFFAVSMFDQNVTRCLFPVPSEETKEILTSLPFVIGVICGAFFLAFPTRRHGIGSPLTKE
What is the function of this protein?
Involved in membrane remodeling.
What are the official names of this protein?
Protein DMP7, AtDMP7.
What is the protein family that this protein belongs to?
Belongs to the plant DMP1 protein family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: FEN1_SCHJY
Sequence: MGIKGLSQVIADNCPSAVRHNDIKNYFGRKVAIDASMSLYQFLIQVRGQDGQQLMNDQGETTSHLMGMFYRTLRMVDNGLKPCYVFDGKPPTLKSGELAKRASRQQKAREEREEAKEVGTAEMVDKFAKRTVRVTRQHNDEAKKLLELMGIPYVNAPCEAEAQCAALARAGKVYAAASEDMDTMCFQAPILLRHLTFSEQRKEPISEYSFEKTIEGLNFTIEQFVDLCILLGCDYCDPIRGVGPARAVELIRQHGNLDNFVKDADKKKFPIPEDWPYQDARRLFLEAEVQEAKDIELKWRAPDEQGIIKFLVEEKGFNEDRVRVGINRLVKASKTIPQGRLDSFFKVLPSTKKEKEKPKAAAKRKRDTKSSAPKKKR
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: DDB2_HUMAN
Sequence: MAPKKRPETQKTSEIVLRPRNKRSRSPLELEPEAKKLCAKGSGPSRRCDSDCLWVGLAGPQILPPCRSIVRTLHQHKLGRASWPSVQQGLQQSFLHTLDSYRILQKAAPFDRRATSLAWHPTHPSTVAVGSKGGDIMLWNFGIKDKPTFIKGIGAGGSITGLKFNPLNTNQFYASSMEGTTRLQDFKGNILRVFASSDTINIWFCSLDVSASSRMVVTGDNVGNVILLNMDGKELWNLRMHKKKVTHVALNPCCDWFLATASVDQTVKIWDLRQVRGKASFLYSLPHRHPVNAACFSPDGARLLTTDQKSEIRVYSASQWDCPLGLIPHPHRHFQHLTPIKAAWHPRYNLIVVGRYPDPNFKSCTPYELRTIDVFDGNSGKMMCQLYDPESSGISSLNEFNPMGDTLASAMGYHILIWSQEEARTRK
What is the function of this protein?
Inhibits UV-damaged DNA repair.
What are the official names of this protein?
DNA damage-binding protein 2, DDB p48 subunit, DDBb, Damage-specific DNA-binding protein 2, UV-damaged DNA-binding protein 2, UV-DDB 2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DDB2/WDR76 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Accumulates at sites of DNA damage following UV irradiation.
Protein: FPRS6_MOUSE
Sequence: MEANFSIPQNGSEVVFYDSTTSRVICIFLVVVLSITFLLGVIGNGLVIYVAGFRMTHTVTTICYLNLALSDFSYMASLPFQITSIVMNGEWLFGWFLCKFVHMIINVNLFLSIFLITFIAMDRCICVLHPVWAQNHRTVNVATKVIFGAWILVLMLIFPHCIFVTTVKDESGKVHCICNFESWAATPEEQVKVSMTVSLISVTISFIIGFSIPMIFIVICYGLMAAKIGRRGFVNSSRPLRVLTAVAISFFVCWFPFQLIFLLGNIGNKETQNNIDTWVNTASTLASFNSCLNPILYVFLGQQFRERLIYSLSASLERALREDSALNSDKTRNLSSQRL
What is the function of this protein?
May have an olfactory function associated with the identification of pathogens or of pathogenic states.
What are the official names of this protein?
Formyl peptide receptor-related sequence 6.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: P22_ASFM2
Sequence: MSTLLIALIALIVLLIIILVVFLYYKKQQPPKKVCKVDKDCGSREHCVRGTCSSLSCLDAVKMDKRDVKMDSKISSCKFTPNFYHFTDTAAEQEFGKTWHSIKITPSPGESHTSQEICERYCLWGTDDCTGWEYFGDEKNGTCNIYNNPYLALKYTKDHVLYLPRNHKYA
What are the official names of this protein?
Inner membrane protein p22.
What is the protein family that this protein belongs to?
Belongs to the asfivirus inner membrane protein p22 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein. Host cell membrane; Single-pass membrane protein. Note=Part of the virion inner membrane.
Protein: PYRB_NEIMA
Sequence: MPNPLYRQHIISISDLSREQLECLLQTALKLKAHPRGDLLEGKLIGSCFFEPSTRTRLSFETAVQRLGGKVIGFSDGANTSAKKGETLADTARIISGYTDAIIQRHPKDGAARVAAEFSRVPVINAGDGTNQHPSQTLLDLVTIYETQGRLDKLKIAMAGDLKYGRTVHSLCQALKRWNCEFAFVSPPSLAMPDYITEELDEAGCRYRILGSLEEAAEWADILYMTRVQRERFDEQEFAKIQGKFNLEASMLARAKPNLRVLHPLPRVDEIHPDVDATPHAYYFEQATNGVYARMAILSLVLNEEV
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: DUT_BRUA2
Sequence: MTAASSSAPTLGIIRLEHAKGLDLPAYETAGSAGMDLRAAVAEDRQIVLLPGRRTLVPTGLILEIPQGYEVQIRPRSGLAFKNGITCLNTPGTIDSDYRGEVKVLLINLGDDDFRIERGMRIAQAVFAPVIQPKIEERAKISETARGAGGFGSTGTA
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RAB4A_HUMAN
Sequence: MSQTAMSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKDLDADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRAQAPNAQECGC
What is the function of this protein?
Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state (PubMed:15907487, PubMed:16034420).  Involved in protein transport (PubMed:29425100).  Plays a role in vesicular traffic.  Mediates VEGFR2 endosomal trafficking to enhance VEGFR2 signaling (PubMed:29425100).  Acts as a regulator of platelet alpha-granule release during activation and aggregation of platelets (By similarity).
What are the official names of this protein?
Ras-related protein Rab-4A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Cytoplasm. Early endosome membrane; Peripheral membrane protein. Recycling endosome membrane; Peripheral membrane protein. Note=Generally associated with membranes. Cytoplasmic when phosphorylated by CDK1.
Protein: THIK_SALDC
Sequence: MRSNNNNPLTRDEILSRYFPQYRPAVAASQGLSGGSCIIAHDTHRIVLRRHHDPDAPPAHFLRHYRALSQLPASLAPRALFYTPGWMAVEYLHGVVNSALPDADELAALLYHLHQQPRFGWRIALSPLLAQYWSCCDPARRTPFWLRRLKQLQKNGEPRPLRLAPLHMDVHGDNIVLTSAGLRLIDWEYAGDGDIALELAAVWVEDERQHRQLADAYAARARIDARQLWRQIRLWHPWVIMLKAGWFEYRWRQTGEQQFIRLADETWRQLRMKG
What is the function of this protein?
Catalyzes the phosphorylation of thiamine to thiamine phosphate.
What are the official names of this protein?
Thiamine kinase.
What is the protein family that this protein belongs to?
Belongs to the thiamine kinase family.
Protein: RUVB_MYCLB
Sequence: MSEDYLDRDVSPALTVGEADIDVSLRPRSLREFIGQPRVREQLQLVIEGAKNRGATPDHILLSGPPGLGKTSLAMIIAAELGSSLRMTSGPALERAGDLAVMLSNLVEHDVLFIDEIHRIARPAEEMLYLAMEDFRVDVIVGKGPGATSIPLEVAPFTLVGATTRSGALTGPLRDRFGFTAHMDFYEPTELEGVLARAAGILGIELGVEAGAEIARRSRGTPRIANRLLRRVRDFAEVRADGVITRDVAKAALAVYDVDELGLDRLDRAVLSALTRSFGGGPVGVSTLAVAVGEEATTVEEVCEPFLVRAGMVARTPRGRVATAQAWTYLCMTPPVGVTGLSQPGLFES
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RXL7_STAAM
Sequence: MSKEKVARFNKQHFVVGLKETLKALKKDQVTSLIIAEDVEVYLMTRVLSQINQKNIPVSFFKSKHALGKHVGINVNATIVALIK
What are the official names of this protein?
Putative ribosomal protein L7Ae-like.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
Protein: IBBB1_HYAOR
Sequence: GQQPLCNDCFACARSLCICGDLVPQCHEGCQQCEKVDTGKPLYQCRSFEDYQCAN
What is the function of this protein?
Serine protease inhibitor (PubMed:33666645).  Weakly inhibits trypsin (Ki = 167 nM) (PubMed:33666645).  Does not inhibit bacterial subtilisin or mamallian chymotrypsin (PubMed:33666645).
What are the official names of this protein?
Bowman-Birk type proteinase inhibitor B1, HOSPI-B1.
What is the protein family that this protein belongs to?
Belongs to the Bowman-Birk serine protease inhibitor family.
Protein: NRDG_HAEIN
Sequence: MNYLQYYPTDVINGEGTRCTLFVSGCTHACKGCYNQKSWSFSAGVLFDDVMEQQIINDLKDTRIKRQGLTLSGGDPLHPLNVETLLPFVQRVKRECPDKDIWVWTGYKLDELDKQQRAMLPYIDVLIDGKFIQEQADPSLVWRGSANQIIHRFKL
What is the function of this protein?
Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
What are the official names of this protein?
Anaerobic ribonucleoside-triphosphate reductase-activating protein, Class III anaerobic ribonucleotide reductase small component.
What is the protein family that this protein belongs to?
Belongs to the organic radical-activating enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR7_CHAGL
Sequence: MSRRKNAEKRIVNPDPVYRNRLVNMLVNRILKNGKKSLAYRILYKAMKNIKTKTQKNPLFILRQAIRKATPKVAVKARRVGGSTYQVPVEIQSSQGKALAIRWLLTSAKKRAGRNFISKLSNEIIDTARDTGNTIRKKEETHRMAESNRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SH321_MACFA
Sequence: MVQSELQLQPRAGGRAEAASWGDRGNDKGGFGNPDMPSVSPGPQRPPKLSSLAYDSPPDYLQTVSHPEAYRVLFDYQPEAPDELTLRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFVLPPPPIKKLVPRKVVSRQSAPIKEPKKLMPKTSLPTVKKLATAATGPSKAKTSRTPSRDSQKLTSRDSGPNGGFQSGGSCPPGRKRSKTQTPQQRSVSSQEEEHSSPAKAPSVKRTPMLDKTTTPERPPAPENAPGSKKIPVPDKVPSPEKTLTLGDKASIPGNSTSGKIPGPDIVPTPERMVTPEDKASIPENSIPEEALTVDKPSTPERLSSVEEASGPEVPPMDKVPDPKMAPLGDEAPTREKVLTPELSEEEVSTRDDTQFHHFSSEEALQKVKSFVAKEAPSSQEKAHTPEAPPLQPPSSEKCLGEMKCPLVRGDSSPHQAELKSGPASRPALEKPHPQAEATTLLEEAPSKEERTPEEEASPNEERLLRGEVLPKEGVASKGEVLPKEGVASKGEVLPKEGVASKEVLPKGGVASKEEVLPKEGVASKEEMLPKEGVASKEEVTLKEEVAPKEEVPPIDTAFAQKTHPIKPSPDSQETLTLPSLLPQNYTENKNEGVDVTSLRGEVESLRRALELMGVQLERKLTDIWEELKSEKEQRQRLEVQVMQGTQKSQTPRIIHAQTQTY
What are the official names of this protein?
SH3 domain-containing protein 21.
Protein: CAS2_THEKO
Sequence: MYIIVVYDVSVERVNRVKKFLRQHLHWVQNSVFEGEVTLAEFERIKAGIGELIDGDEDSVVIYKLRSMPKREVMGVEKNPIEDII
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Functions as a ssRNA-specific endoribonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: MTNA_PSEE4
Sequence: MREQLMAAETVTGIEWHDGALHLLDQRLLPLEQCWLTCTDVAQVAEAISEMVVRGAPAIGISAAYGLVLALRQRLAEGEGWEESLEEDFLMLGEARPTPANLFWALNRMRERLQRLRPGDDVLAVMEAEAIAIHESDREANLTMAQFGVEQIRKHQGSEQALLTHGNAGALATGGFGTALGVIRAATLEGMVEQVYVCESRPWLQGSRLTAWELAADGVPVTVVADAAAGHLMKTKGISWVVVGADCIAANGDVAAKIGTYQIAVAAMHHGLRFMVVAPSSSIDLNLATGEDIPLETRGVEELLEVAGIQVTADVEVYNPVVDVTPADLIDVIVTEKGVVERPDAAKIAQLMCRKRLH
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: PDXS_BACLD
Sequence: MAQTGTDRVKRGMAEMQKGGVIMDVVNAEQAKIAEEAGAVAVMALERVPADIRAAGGVARMADPTIVEEVMNAVSIPVMAKARIGHIVEARVLEALGVDYIDESEVLTPADEEFHLNKNEFTVPFVCGCRDLGEATRRIAEGASMLRTKGEPGTGNIVEAVRHMRKVNAQVRKVVGMSDDELMTEAKNLGAPYELLKEIKAEGRLPVVNFAAGGVATPADAALMMQLGADGVFVGSGIFKSDNPAKFAKAIVEATTHFTDYKLIAELSKELGTAMKGIEISNLLPEQRMQERGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: FBX6_RAT
Sequence: MVNINELPENILLELFTHVPAPQLLRNCRLVCSLWRDLIDVMTLWKRKSLREGFVTKDRDEPVDDWKIFYILCSLQRNLLRNPCAEENLRSWRIDSNGGDEWKVESLPGDHGTSFPDTKVKKYFVTSYGMCLKSQMVDLKAEGYSEKLLDTVRPDIVVKDWFAPRADCGCTYHLRVQLASADYIVLASFEPPPVTIEQWNDASWQEISHTFSNYPPGVRHILFQHGGKDTQFWKGWYGPRVTNSSIIVSHRTAKNPAPARTLPEEDTSNRRKILSFGSWEDLSP
What is the function of this protein?
Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complexes.  Involved in endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation.  Able to recognize and bind denatured glycoproteins, which are modified with not only high-mannose but also complex-type oligosaccharides.  Also recognizes sulfated glycans.  Also involved in DNA damage response by specifically recognizing activated CHEK1 (phosphorylated on 'Ser-345'), promoting its ubiquitination and degradation.  Ubiquitination of CHEK1 is required to insure that activated CHEK1 does not accumulate as cells progress through S phase, or when replication forks encounter transient impediments during normal DNA replication (By similarity).
What are the official names of this protein?
F-box only protein 6, F-box only protein 6b, F-box protein that recognizes sugar chains 2, F-box/G-domain protein 2.
What are the subcellular locations of this protein?
Cytoplasm.