PharMolix/UniProtQA huggingface dataset:
Protein: H3C_XENLA
Sequence: MARTKQTARKSTGGKAPRKQLVTKAAKKCAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQRSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.3C.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SYFB_PLAVS
Sequence: MPTISVHEEDLIEKLGEKIEEEKLNDICFEFGIEIDDVEYKGEKKIYKIEVPANRYDLVCVEGLCRALKSFIGKYENVSYALLTNSEEACVKEKHFMRVDESVDERRSYVVSAVLKNVKMNENVYNNIIELQEKLHHNLGKKRILLAIGIHDYDKINFPVAYKFEEKEKINFIPLNETQNVNGNNFINFYQDNINLKSYLKIISDFEKFPVIVDAGGQILSLPPIINCDYTKITYDTRNLFIECTAIDRNKAEIAVNIICSMLSEYCTPKYSIHSFFVQYDKNHKAEKGNGYLYPVFKNKTLTCHMDYVRKLSGILNLSVKDVEPLLKKMMITSKVIDSSTFTVDVPFYRSDIMHFCDIVEDIAIAYGYGNIVSEKIEIAKKNSLSACTELFRNVLAECTYTEVMTNALLSKRENYDCMLRKHRSYDDRKINLDEYNPLAPPVQIMNSKTSEYEIVRTSLIVNMLKFVSANKHRELPLRFFEIGDVSYTTYDRTDTNAVNKRYLSVIFADKFTAGLEEAHGMLETVLKEFQLFSDYKIEEKSKENVAIRSDVFYKLVPKEDPSFLNERVVDIVLCPHNLKFGIMGIIHPKVLENFSIDIPVSVIEINIETIMDVLMM
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanine tRNA-synthetase beta subunit, FRS, PheRS, Phenylalanyl-tRNA synthetase beta subunit.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: CLPX_PSEMY
Sequence: MTDTRNGEDNGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVDLCNDIIREEVQEAQAESSAHKLPAPKEISAILDQYVIGQERAKKVLSVAVYNHYKRLNQRDKKDDVELGKSNILLIGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQMGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTRNILFICGGAFAGLEKVIQARSTKGGIGFGAEVRSKQEGKKIGESLREVEPDDLVKFGLIPEFVGRLPVIATLEELDEAALVQILTEPKNALTKQYAKLFEMEGVDLEFRSDALKSVAQRALERKTGARGLRSILEGILLDTMYEIPSQQDVSKVVIDESVIDGSSKPLLIYENSEPQAKAAPDA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: THIG_BURTA
Sequence: MTLLSSADTLTLHGQTFASRVLLGTSRYPSLQSLSDSIAAARPGMVTVALRRQMNAGAAEAGFFDLLKRHDVPLLPNTAGCQTIAEAVTTAQMAREVFETDWIKLELIGDDYTLQPDPVGLIEAAALLVKDGFKVLPYCTEDLVIARRLLDAGCEALMPWGAPIGTGKGVVNPYGLRVLRERLPDVPLIVDAGLGVPSHACQVMEWGFDGVLLNTAVSQATHPEIMARAFAQGVDAGRAAYLAGPMDARESAHASTPVVGMPFWHQDGSHA
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_METNO
Sequence: MDSFKPYLAKVATGAALTREEARTAFDHLLSGEVTHAQAGAFLMALRVRGEAADEIVGAAGALRERMVRVAAPPGAIDIVGTGGDHSGSYNVSTLAAIITASCGVPVAKHGNRAASSRSGAADVLAALGVRLGLDPEALAQCLAQAGLCFMFAQTHHASMRHVAPVRVELGTRTLFNVLGPLCNPAGVSGQLFGVYAASLAEPLTRVLADLGSTRVWTVHGSDGLDEITTTGPTAVVALEDGAIRRFTIDPRELGLALAAPEDLRGADPEHNAAALRAVLDGARTPYRDIAVLNAAAALVVAGAAANLGEGVARAAQAVDSGAARATLDRLVAVSNA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: RS4_CHLSY
Sequence: MARYIGPVGKVSRRLGIGITEKGLRILNKRSDPPGQHGAAARRRQLSDYGMQLREKQKAKFLYGVLERQFRRLFEQASRRSGVTGEYLLSLLERRLDNVVYRLGFATTRAQARQLVNHGHIVVDGRKTNIPSYTVKVGQVIAVRPQSRSRTYFKNLVDSGVLNKHRAPEWLRLNAAELSGTVVALPRREDAEAGINEQLIVEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: ATPB_PIPCE
Sequence: MRINPTTSGPGVSTLEEKNQGRIVQIIGPVLDVAFSPGKMPNIYNALIVKGQDTVGQQINVTCEVQQLLGNNRVRAVAMSATDGLTRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYIEMKESGVINEQNLAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQRVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLPETIRGFRLILSGELDGLPEQAFYLVGNIDEATAKAMNLDEESKLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: CCJ18_ORYSJ
Sequence: MDEDRAVEAAASAWPGPSRRRRLIEFLLHASTRLDLRPVVKYTALSFFADRLLPSLRRKMGFCGARGGRAVTSWLLEPLRDSNLELFALVAVWIASKIHELKPLSVKSLKALGDRIIADQHFTCRDFANAELVFMEVVEYNIGSLNIAFTYLEELLVQFREISKIGDLLNMDVCMEILDILYETEDSSWLFNSPCQLAASALVTAYAISVPKQRWEFPILPWVTFTTSYDEEEIMKVVLTILMHVLKPDEMKGKGERDFNI
What are the official names of this protein?
Cyclin-J18-like.
What is the protein family that this protein belongs to?
Belongs to the cyclin family.
Protein: RS21_PARL1
Sequence: MQVLVRDNNVDQAMKALKKKLQREGVFREMKLRNFYEKPSEKRAREKAEAIRRARKLARKRAQREAGIVTAKK
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: YN8P_YEAST
Sequence: MVQPAPLITNAPTPKIPNIPAVALNVAPCIMAPISIDQLQGKYNSHVPTGFSSLISSAYGIHFLGSRDTNGPSPSNLSFLATSNSFDVNTGADSFEEGEEEEEEEDVYLFLLLPMIPATVTRPLPRMDLPSKILFLCQINIS
What are the official names of this protein?
Putative uncharacterized protein YNR042W.
Protein: RS4_LIMRJ
Sequence: MSRYTGPSWRVSRRLGVSLSGTVKELARRAYAPGDHGRDRRGKLSEYGTQLREKQKLRFMYGMTERQFSNLFVRAGKIKEGTHGANFMALLERRLDNMVYRLGLATTRRQARQLVNHGHITVDGKRVDIPSYEVKVGQIIAVRDKSKNLDIIKNAVEAVVSRPSYVDFDADKLEGKLNRIPAREDMNADIDEALIVEFYNK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: PURA_SYNC1
Sequence: MANVVIVGAQWGDEGKGKVVDIYTEHADDVVRFQGGNNAGHTLVVGEETTILHLIPSGILHEGKRCIIGNGVVLDPKVFLEEIGQLKKKGYLKDDKQLVIDGNAHIIMPYHKALDIAREQKSGARKIGTTGRGIGPTYEDKVARRGIRVMDLVHPDTFVRKVKEMLPEKNFYLEQYLGGEPLSEEAIVEEYSVYARELAKYVDRASLLLNRSIAEGRNVLFEGAQGALLDIDHGTYPYVTSSSTVAGGACTGSGVGPTVIDEVVGIVKAYVTRVGEGPFPTELHDEMGEKLRSEGHEFGSTTGRPRRTGWFDAVAMREAVRISGMTGLALTKMDVLNGLDTINVCTAYSYQGELLEDFPHDLDILKECKPVYEQVEGWQVDLEGATSFETLPPKAQAYLRKIEEVSGCPVVLVSIGPRRDQTIQLKNPFDK
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPPA_SYNY3
Sequence: MKNFFQQMVASFFGTLAAIVVLLSLGATGLVLLFILVSAEADPVLEEKTALILDLAIPIQDTSPTLSLQQSLLGNQEEILPLRTVVNAIEKAAEDDRIVALLIDGRRSNQVDGYANLSEVQQALIKFKQSGKKIVAYGLNYSELGYYLAATADTILINPMGGVEINGLGAQPIFFTGALAKAGIGVQTLRVGSYKGAVEPYTRENLSPENRQQQQLLLNQIWQIYLTSVANNRSLTVPQLQAIASDQGLLFADIALREKLVDKVTYWDEVLAELKQAGVWINDPEKIEEQEEDKEFRKISLAEYHRLQNWETENHDQDPKIAIVYLEGSIVNGRGTWENIGGDRYGELLRTIRQDDDIKAVVLRINSPGGSASAADIIWREVELLQAQKPVIISMGNVAASGGYWIATAGEKIVAQPNTVTGSIGVFSILFNVENLGDRLGLNWDEVATGELANVGSSIKPKTELELAIFQRSVDQVYEIFLDKVGRARNLSPTALDSVAQGRVWTGLAAQKVGLVDQLGGLQTAVNLAAAQAELGEQWQVKEYPTPRGLNSLLWNNLIHGLTETNSVVLPPFLRTNWQQLEREWAELAQFNDPQGIYARLPFSWHFLNP
What is the function of this protein?
Digests cleaved signal peptides in vitro, its in vivo function is unknown.  This activity is necessary to maintain proper secretion of mature proteins across the membrane (By similarity).
What are the official names of this protein?
Protease 4, Endopeptidase IV, Protease IV homolog, Signal peptide peptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S49 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: FDOH_ECOLI
Sequence: MAYQSQDIIRRSATNGLTPAPQARDFQEEVAKLIDVTTCIGCKACQVACSEWNDIRDTVGNNIGVYDNPNDLSAKSWTVMRFSEVEQNDKLEWLIRKDGCMHCSDPGCLKACPAEGAIIQYANGIVDFQSEQCIGCGYCIAGCPFDIPRLNPEDNRVYKCTLCVDRVVVGQEPACVKTCPTGAIHFGTKESMKTLASERVAELKTRGYDNAGLYDPAGVGGTHVMYVLHHADKPNLYHGLPENPEISETVKFWKGIWKPLAAVGFAATFAASIFHYVGVGPNRADEEENNLHEEKDEERK
What is the function of this protein?
Allows to use formate as major electron donor during aerobic respiration.  The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.  Electrons are transferred from the gamma chain to the molybdenum cofactor of the alpha subunit (By similarity).
What are the official names of this protein?
Formate dehydrogenase-O iron-sulfur subunit, Aerobic formate dehydrogenase iron-sulfur subunit, FDH-Z subunit beta, Formate dehydrogenase-O subunit beta.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SYI_LEPBL
Sequence: MSETQKENPYSSTVLLPKTDFPMKADLAKREPEQIRSWKQNRIFRKMREQRSGKKEFVLHDGPPYANGNFHLGHALNKILKDTIIKSKSLAGFYADMIPGWDCHGLPIEVQVLKNLGKKVRETGPEELRQLCRKYAEEFVGKQGDDLSRFLCFWDEGRIYKTMSPDFEAKIVEVFGELFKKGYVYRGKKPVYWSIDLATAHAEAEIEYYPHISPSIYVKFPIIGEKKRFCLIWTTTPWTLPANLAICFNRKIEYSIFKTESSEELILADALAENVTITTGVALTKLKPITSEELAALKFQHPFVDRISVSLFGDHVTLEAGTGCVHTAPGHGQDDYKVGLAAGLEPFSPVDDYGRYTDEFPLMQGKKVFDANPEIIQLLRDKGLLLYHGELEHSYPHSWRSKKPLIFRATPQWFFKIDFQDLREKSLSAIDGVRWIPSWGITRIRSMVETRPDWCLSRQRNWGVPIPAFTCESCGQTHIDDASIQFFTKMVREKGIEIWYSEETKDLLPPKTKCGKCGNDSFKKGNDILDVWFDSGVSNFSVLGERKDEPPADLYLEGSDQHRGWFQSSLWPSMALRGIPPYKAVLTHGYVLDEKGRAMSKSLGNGIDPTADIIQVYGADILRLWVSSLDFRDDIKVGKESLKIVSEQYRKIRNTFRYLLGNLDGHTPEQNLPFEELEELDRFYLSKLAGFVEDAVASYETYQFHQIYQKLILFCTVTLSQDYFDMIRDRMYCDLRDSKSRRSSSTALQYILDSLCILVAPILSFTAEEVWTSNGKKDSVFLQTFPDLKSWKNQSLEDKFESALQAREVVQKALEIARQEGKLGKSLEAALEIVSKSGLSFGELLPKETLELLFVVSQIHEENPGMEVLSSHENEKFSVKVLKPLQGECPRCWRHTEDISKEGDLCGRCKSVVA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAC7_ORYSJ
Sequence: MSTARFIKCVTVGDGAVGKTCMLISYTSNTFPTDYVPTVFDNFSANVVVDGNTVNLGLWDTAGQEDYNRLRPLSYRGADVFLLAFSLISKASYENIHKKWIPELRHYAPNVPIVLVGTKLDLREDKQFFLDHPGLAPISTAQGEELKRMIGAAAYIECSSKTQQNVKSVFDSAIKVVLCPPKPKKKNTRKQRSCWIL
What is the function of this protein?
Inactive GDP-bound Rho GTPases reside in the cytosol, are found in a complex with Rho GDP-dissociation inhibitors (Rho GDIs), and are released from the GDI protein in order to translocate to membranes upon activation.
What are the official names of this protein?
Rac-like GTP-binding protein 7, GTPase protein ROP5, OsRac7.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Note=Associated with the membrane when activated.
Protein: RNPA_AGRFC
Sequence: MSETKKQPGRLKNRSEFLAVQAGEKRRGSTFLVEVLDRRAPETEPRVGFTVTKRQGNAVERNRMRRRLKEAVRLSAGVAMKPGHDYVIVARRDVLDTAFPKLQSLLIERIEGTAKPKRSQETRSRKE
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: RL28_OLEA2
Sequence: MGKQCEFCGKKPQTGNNVSHSNIKTKRRFMPNLQSARHQLPTGQIKTVSVCTRCLRSGAVVKPVVKKTA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RK22_OROMI
Sequence: MLKNKTKKTEVYALCRHISLSADKARRVIDQIRGRSYEETLMILELMPYRACYPILKLVYSAASNAAYSMDSAEVNLVISKAEVNEGTITKKFKPRARGRSYVIKRTTCHITIVVKDISLDKYEEIYSFKNPIWKNTIDVYSNGVVWHKK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, plastid.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid.
Protein: MX2_CANLF
Sequence: MSKAHGSRPYRRHNVVIPRQQPEKEMNFVQQQPPPSDAAARQMMYPPNCQVGVQDPVYLAKEFNLLTLNPQQLEGSRHQQMAKGPEKSLYSQYEQKVRPCIDLVDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKRDPHKAWRGRISYRKTELQFQDPSQVEKEIRQAQNIIAGQGLGISHELISLEITSPEVPDLTLIDLPGITRVAVGNQPQDIGVQIKALIKNYIQKQETINLVVVPCNVDIATTEALSMAQEVDPNGDRTIGVLTKPDLVDRGTEKTVVNVAQNLTYHLQKGYMIVRCRGQEEITNQLSLAEATEKERMFFQTHPYFRALLEEGKATVPCLAERLTKELILHINKSLPLLEKQIRESHQRATDELHQCGDSIPSNEADKMFFLIEKIKLFNQDIDKLIEGEEIVKKNETRLYNKIREEFEHWALVLTANTQKVKNIVSEEVSVYEKQYRGKELLGFVNYKTFETIVHQYIEQLVEPALTMLRKTIEIVWQAFTDTAKKHFSVFSNLSQTIQNKIEDIKTRQAETAENLIRLQFRMEQLVYCQDQIYSVVLRKVRKEVFNPAGKAAQDLQLKFPFPKDLPSMSSNDEIGVHLNAYFLETSKRLANQIPFIIQYFVLQENGSCLQKAMMQILQEREQYSWLLQEHADTSAKRRFLKEKIYRLAQARRALYMFFS
What is the function of this protein?
Interferon-induced dynamin-like GTPase with antiviral activity against vesicular stomatitis virus (VSV).
What are the official names of this protein?
Interferon-induced GTP-binding protein Mx2, Myxovirus resistance protein 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SUCC_SHIDS
Sequence: MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWGVKCQVHAGGRGKAGGVKVVNSKEDIRAFAENWLGKRLVTYQTDANGQPVNQILVEAATDIAKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQGRELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGADGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGEPANFLDVGGGATKERVTEAFKIILSDDKVKAVLVNIFGGIVRCDLIADGIIGAVAEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKGLTDAAQQVVAAVEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: HOXQ_CUPNH
Sequence: MNSFPIPVVLLGPGSQAEDETLDYIHMPQGMSVYTPPVLPEPEQIACLTQAQSVLRAILDALDRADPKQPNPRIELWALDEENRQLLKQVLGEGEVSARIEGEYQVYIQEAVFAGVWRVVSTCPDATTDYIEVGAAPEVLRGAARYGANQWSLDVGRVPDGVMNAPSILAEIDDQLLSWHPGKPVHVVNLTLLPMSPQDITFLDETLGAASVTILSRGYGNCRISSTAVPYCWRVVYFNSQDTTILNTVEITDLPEVACAAPEDLRDSHERLTEVLKWVGSI
What are the official names of this protein?
Hydrogenase expression/formation protein HoxQ.
What is the protein family that this protein belongs to?
Belongs to the HupH/HyaF family.
Protein: MDTD_ECO5E
Sequence: MTDLPDSTRWQLWIVAFGFFMQSLDTTIVNTALPSMAQSLGESPLHMHMVIVSYVLTVAVMLPASGWLADKVGVRNIFFTAIVLFTLGSLFCALSGTLNELLLARALQGVGGAMMVPVGRLTVMKIVPREQYMAAMTFVTLPGQVGPLLGPALGGLLVEYASWHWIFLINIPVGIIGAIATLMLMPNYTMQTRRFDLSGFLLLAVGMAVLTLALDGSKGTGLSPLAITGLVAVGVVALVLYLLHARNNNRALFSLKLFRTRTFSLGLAGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQVVNRFGYRRVLVATTLGLSLVTLLFMTTALLGWYYVLPFVLFLQGMVNSTRFSSMNTLTLKDLPDNLASSGNSLLSMIMQLSMSIGVTIAGLLLGLFGSQHVSVDSSTTQTVFMYTWLSMAFIIALPAFIFARVPNDTHQNVAISRRKRSAQ
What are the official names of this protein?
Putative multidrug resistance protein MdtD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRMD_RICPU
Sequence: MSILHATILTVFPEMFPGTLGHSLAGQALNKNIWSYDVINIRDFGLTKHKNIDDEAYGGGNGLIMRPDVLGSSIDHALALNPNAEMYYPSPRGRVFTQSFAKEMLKNKNLIFLCGRYEGIDERVIEEYNVKEISVGDYILSGGEMPTLTILDCLIRLLPGVLMNQNTLSSESFEEDGEFKGGLECSLYTRPEIWRDRAVPSVLLSGNHRLINEWKKEQSHMITKLRRPELLKDL
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF1_DINSH
Sequence: MSIDWITVAAQIVNFLLLIWLLKRFLYRPILDGIDAREAEIAARMGEAAAVRQQAEARETEYEARIAQLSSSRAELLEEARRAAEAERDALLSKARARLEEEQAERAAHRAEEAARHRADLQRRGAEALLALTRKALRDLADEGLERRIVLQAAGRLADMGDDLREAAGDARQAVALTRDPLPEEVQARLRSDLGDVLEGVSLRFEVDPGQSPGLNLRLGGAQLGWTVDSYLNGLEATLAEAAGRPARRGGHDAA
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 1, ATP synthase F(0) sector subunit b 1, ATPase subunit I 1, F-type ATPase subunit b 1, F-ATPase subunit b 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: UVRA_BRUME
Sequence: MSDQKFISIRGAREHNLKNVDLDLPRDKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLEMMQKPDVDQIDGLSPAISIEQKTTSRNPRSTVGTVTEIYDYMRLLFARVGIPYSPATGLPIESQTVSQMVDRVIALEEGTRLYILAPIVRGRKGEYRKELAELQKKGFQRVKVDGTFYEIADVPPLDKKYKHDIDVVVDRVVVRPDLSTRLADSLETCLKLADGLAIAEFADKPLPVGETAEGGSANKSANETHERILFSEKFACPVSGFTIPEIEPRLFSFNNPFGACPTCDGLGTQQAIDPNLIIPDESAALKDGAVAPWARSSSPYYNQTLEALGKAYGFKVSARWSELSEEARQAILYGTKGREITFHYDDGLRSYQTTKPFEGVIPNLERRWKETDSAWSREEIERFMASTPCPACNGYRLKPEALSVKIGKKHIGEITEMSIRKADAWFRDIDGSFNEKQREIAARILKEIRERLQFLNDVGLDYLTLARNSGTLSGGESQRIRLASQIGSGLTGVLYVLDEPSIGLHQRDNARLLDTLRHLRDLGNTVIVVEHDEDAILTADYVVDIGPAAGVHGGKVIAQGSPQDIMANTNSLTGKYLSGAMEVAVPAERRKISKTKRLRVVGARGNNLKNVSADIPLGTFTAVTGVSGGGKSTFLIETLFKAASRRIMGSREHPAEHDRIEGLEFLDKVIDIDQSPIGRTPRSNPATYTGAFTPIRDWFAGLPEAKARGYQPGRFSFNIKGGRCEACQGDGVIKIEMHFLPDVYVTCDVCHGKRYNRETLDVLFKGKSIADVLDMTVEEGAEFFSAVPAVRDKLETLVKVGLGYIKVGQQATTLSGGEAQRVKLAKELSRRATGRTLYILDEPTTGLHFHDVAKLLEVLHELVEQGNTVVVIEHNLEVIKTADWVIDLGPEGGDGGGEIVAVGRPEDIVQEKRSYTGQFLKELLERRPKRSSQAAE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_PSEA8
Sequence: MTQAFTVVIPARYASTRLPGKPLQDIAGQPMIQRVWNQARKSAASRVVVATDDERILAACQGFGAEALLTRAEHNSGTDRLEEVASRLGLASDAIVVNVQGDEPLIPPALIDQVAANLAAHPEAAIATLAEPIHEVSALFNPNVVKVATDIDGLALTFSRAPLPWARDAFARDRDSLPEGVPYRRHIGIYAYRVGFLADFVAWGPCWLENAESLEQLRALWHGVRIHVADARETMLPGVDTPEDLERVRRVLGG
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BTBD9_MOUSE
Sequence: MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKHFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLRYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLASDGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNAKENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRLLLWDRDSRSYSYFIEVSMDELDWIRVIDHSHYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKAFTLEKGLIVPLENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYIIGSIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVGTHNTANEVFHCVHFECPEQQSNQKEDSSEEPGTGDPSTPNQQLDPHAPRAPSASSLPPSPGPNSRSPNQQNQ
What are the official names of this protein?
BTB/POZ domain-containing protein 9.
Protein: SECD_PSEAE
Sequence: MLNKYPLWKYLLILAVLAVGFIYSAPNLYPDDPAVQISGASTALQVTQADVDRAAKALTDAGIAVKADSLSKKGGLIRLVKQDDQLPAKEVVRRTLGDDYVVALNLAQTTPEWLRKLGGSPMKLGLDLSGGVHFLLEVDMDKAVDARLKVYESEVKSLLRKERVRYRSLPIQDRAIQLGFTDSESLDKARSLIAKDFRDFEVVPEERNGLQVLRVALTQAKLAEIREYSIKQNLTTVRNRVNELGVSEPLVQRQGANRIVVELPGVQDTAEAKRILGKTANLEFRLAAEPDALKSATETFEFREPRRPPVPLERGVIITGDQVTDASASFDENGRPQVNIRLDGHGGELMNRATRNNVGRSMAVVFIEQKPVTRYTKQMVDGVEKEVAVPAFKEEKQIISLATIQSPLGNQFRITGLDGPGESSELALLLRAGGLAAPMYFAEERTIGPSLGADNIAKGIDASLWGMLFVSLFIIVIYRFFGVIATVALAFNMVMLVALMSILGATLTLPGIAGIVLTMGMAVDANVLIFSRIREELANGMSVQRAIHEGFNRAFTAILDANLTSLLVGGILYAMGTGPVKGFAVTMSLGIITSMFTAIMVTRAMVNLIFGGRDFKKLWI
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecD.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.