PharMolix/UniProtQA huggingface dataset:
Protein: IHFB_BURPS
Sequence: MTKSELVAQLASRFPQLVLKDADFAVKTMLDAMSDALSKGHRIEIRGFGSFGLNRRPARVGRNPKSGEKVQVPEKHVPHFKPGKELRERVDGRAGEPLKNDEPEDAQ
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RIMO_CAMJD
Sequence: MSKLYLMSLGCNKNLVDSEIMLGRLSAYELCDEPSKADVLIVNTCGFIDSAKKESINAILDLHEQRKKDSLLVVTGCLMQRYREELMKELPEVDLFTGVGDYERIDEMILKKTNLFSNSTYLQSENSKRIITGSNSHAFIKIAEGCNQKCSFCAIPSFKGRLKSRQINSIIAELKDLVARGYKDFSFIAQDTSSYLFDKGEKDGLIRLIDEVEKIKGIRAARILYLYPTSASEALIKRIIASEIFVNYFDMPLQHISDNMLKIMKRGTNSTRLKEMLNLMKSAPNSFLRTGFIVGHPGESEADFEKLCEFVKDFGFDRVSVFAYSKEEDTAAFDMEQVPFKVINKRLKIIEKIVDEVIEKSFEKEVEQKRLVVCTGESSEGEFFIAAKDLRWDREIDGEILINESECGNLEMGQIYECEILQNLDKKLLAKALRKVDAN
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CST26_YEAST
Sequence: MLHQKIAHKVRKVVVPGISLLIFFQGCLILLFLQLTYKTLYCRNDIRKQIGLNKTKRLFIVLVSSILHVVAPSAVRITTENSSVPKGTFFLDLKKKRILSHLKSNSVAICNHQIYTDWIFLWWLAYTSNLGANVFIILKKSLASIPILGFGMRNYNFIFMSRKWAQDKITLSNSLAGLDSNARGAGSLAGKSPERITEEGESIWNPEVIDPKQIHWPYNLILFPEGTNLSADTRQKSAKYAAKIGKKPFKNVLLPHSTGLRYSLQKLKPSIESLYDITIGYSGVKQEEYGELIYGLKSIFLEGKYPKLVDIHIRAFDVKDIPLEDENEFSEWLYKIWSEKDALMERYYSTGSFVSDPETNHSVTDSFKINRIELTEVLILPTLTIIWLVYKLYCFIF
What is the function of this protein?
Acyltransferase with lysophosphatidic acid acyltransferase (LPAAT) activity.  Fatty acyl substrates include 18:0-acyl-CoA, 16:0-acyl-CoA, 17:0-acyl-CoA and 14:0-acyl-CoA (PubMed:20694142).  Responsible for the acyl-CoA-dependent introduction of saturated very long chain fatty acids (VLCFAs) into phosphatidylinositol, transferring saturated FAs with 18 to 26 carbon atoms (PubMed:27462707).  Responsible for the incorporation of stearate into phosphatidylinositol (PubMed:19796168, PubMed:26711260).  Overexpression has an effect on chromosome stability (PubMed:10454593).  Regulates phosphorylation and expression of glycerol-3-phosphate acyltransferase SCT1 (PubMed:22323296).
What are the official names of this protein?
2-acyl-1-lysophosphatidylinositol acyltransferase, Acyl-CoA:lyso-PI acyltransferase, Chromosome stability protein 26, Phosphatidylinositol stearoyl incorporating protein 1.
What is the protein family that this protein belongs to?
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
What are the subcellular locations of this protein?
Lipid droplet.
Protein: UPP_CITK8
Sequence: MKIVEVKHPLVKHKLGLMRENDISTKRFRELASEVGSLLTYEATADLETETVTIDGWNGPVEIEQIKGKKITVVPILRAGLGMMEGVLEHVPSARISVVGIYRNEETLEPVPYFQKLVSNIDERMALVVDPMLATGGSMIATIDLLKNAGCHSIKVLVLVAAPEGIAALEKAHPDVELYTASIDKGLNEHGYIIPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: CHED_XANOR
Sequence: MSTAVQVDDVMRYRDSRFQTIAAKLLPTQYLVVDDDTALTTTLGSCVAACLRDPVLKIGGMNHFLLPEGQIGDGAPARYGSYAMELLINDMLKRGAHRKRIEAKVFGGANVLKGFTSNPVGTRNAEFVRQYLQAEHIPIIAEDLCGIHPRKVWFFATTGRVAVQRLPHAHEAEVAATESAVRARLSKAPVTGGVELFE
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: TRPC_EXISA
Sequence: MSYLTKIIGTKIEEVSGMQPIDVPVTKPISLLHVMSEGFHIISEIKRSSPSKGMIRETVDVAKRARQYEKAGATMISVLTDTTYFNGSFDDLRQVADVVTIPVLCKDFIIDERQLDYAKHYGASVALLIVAALHPTRLHELTRYARSIGLDVLVEVHDEAELRIALELDDVLIGINNRDLKTFEVSLETSIDLMKRYPEVTFVSESGVSTVEAAARLQEAGASAILVGEALMREEDPIRLLEELKTCSLKSVD
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: RIMO_STRAW
Sequence: MPERRTVALVTLGCARNEVDSEELAGRLEADGWQLVEDAEDADVAVVNTCGFVEAAKKDSVDALLEANDLKGHGRTQAVVAVGCMAERYGKELAEALPEADGVLGFDDYTNISDRLQTILNGGIHAAHTPRDRRKLLPISPAERQSAGADVALPGHGAPEGLPEDLPEGLAPESGPRAPLRRRLDGSPVASVKLASGCDRRCSFCAIPSFRGSFISRRPSDVLGETRWLAEQGVKEVMLVSENNTSYGKDLGDIRLLETLLPELAEVDGIERVRVSYLQPAEMRPGLIDVLTSTPKIAPYFDLSFQHSAPDVLRAMRRFGDTDRFLELLDTIRSKAPQAGVRSNFIVGFPGETEADLAELERFLTGARLDAIGVFGYSDEEGTEAATYGHKLDEDVVAARLARVSRLAEELVAQRAEERVGETVHVLVESIDDEEGAVGRAEHQAPETDGQVLFTSGEGLTVGRMVEAKVVGTEGVDLVAEPLPGSLVCTEEAGR
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_OENOB
Sequence: MVNALKEKYVNEVRPALISKFDYTSLMQAPKLEKIVLNMGVGDAVTNSNNLDEAVSELRLIAGQQPVVTKAKKSIAGFRLREGMSIGSKVTLRGTRMYDFLDKLINVALPRVRDFHGTSTKSFDGRGNYTLGIKEQLIFPEINYDDVNRVRGLDIVIVTTAKTDEEGLELLSQLGMPFAK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: Y3503_SERP5
Sequence: MEWLADYWWIILLILVGMIISGIKELRRVDVKRYLADKPELPPHRDNNAEWDDDDDWPKKK
What are the official names of this protein?
UPF0370 protein Spro_3503.
What is the protein family that this protein belongs to?
Belongs to the UPF0370 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RAPZ_SALAR
Sequence: MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTLADRQISAAVSIDVRNMPESPEIFEQAMNNLPDAFSPQLLFLDADRNTLIRRYSDTRRLHPLSSKNLSLESAIDKESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKRERELTMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNFIYQTRSYLELWLPMLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRHRTLEKRKT
What is the function of this protein?
Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ.  When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E.  Consequently, GlmZ is inactivated and unable to activate GlmS synthesis.  Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.
What are the official names of this protein?
RNase adapter protein RapZ.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family. RapZ subfamily.
Protein: RS5_YERPS
Sequence: MSHIEKQAGELQEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNGRVGFGYGKAREVPAAIQKAMEKARRAMINVALNNGTLQHPVKGAHTGSRVFMQPASEGTGIIAGGAMRAVLEVAGVHNVLAKAYGSTNPINVVRATIAALEDMKSPEMVAAKRGKSVEEILGK
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: NOEI_SINFN
Sequence: MEVGRYLKEGLLISLQQRLREFAEGIRKPTSSLKVHRQIVSLLEKPDPVILDIGCNDGSDARRFLQLRPKAQLFCFEPDPRAAARCRENMGPLDRMRLFEVAISDRNGRIDFHPSNGDGDAKEWDLSGSIRQPKNHLSEYQWVRFDGPISVETRRLDDWCSEAGLESIDLIWMDVQGAESDVIAGGKETLTKTRFIYTEYSDQELYEGQLPLRAILDLLPSFELVAQFPRGVEGDVLLRNTKL
What is the function of this protein?
Required for 2-O-methylation of the fucosyl group of Nod factors.
What are the official names of this protein?
2-O-methyltransferase NoeI, Nodulation protein NoeI.
What is the protein family that this protein belongs to?
Belongs to the FkbM methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDK4_SHEEP
Sequence: MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALLRRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPRDVSLPRGAFSPRGPRPVQSVVPELEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKAEGDAE
What is the function of this protein?
Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G(1)/S transition.  Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase.  Hypophosphorylates RB1 in early G(1) phase.  Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals.  Also a substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity.  Component of the ternary complex, cyclin D/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex (By similarity).
What are the official names of this protein?
Cyclin-dependent kinase 4, Cell division protein kinase 4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus membrane. Note=Cytoplasmic when non-complexed. Forms a cyclin D-CDK4 complex in the cytoplasm as cells progress through G(1) phase. The complex accumulates on the nuclear membrane and enters the nucleus on transition from G(1) to S phase. Also present in nucleoli and heterochromatin lumps. Colocalizes with RB1 after release into the nucleus (By similarity).
Protein: TERM_BPPRD
Sequence: MAKKKPVEKNGLVYKEFQKQVSNLKKAGLIPKTLDVRKVKPTKHYKGLVSKYKDVATGGAKLAAIPNPAVIETLEARGESIIKKGGKAYLKARQQINQRGQIVNPFTVRVTKRGEVVRRYRKTTPEGKPVYITQRELPIKFENMEQWLTELKAAGFQLQPGEQIYFTFNGNYSRRTYTSFDEAFNKFMTYDIIIDAVAGKLKVEDEADLVKSVGFQRISGPEAKAYNRNRIVLPEMQFSQAAKKKYKRRQKRGYGSKGV
What is the function of this protein?
Acts as a primer for viral genomic replication.  DNA terminal protein is covalently linked to the 5'-ends of both strands of the genome through a phosphodiester bond between the beta-hydroxyl group of a tyrosine residue and the 5'-phosphate of the terminal deoxyadenylate.  This protein is essential for DNA replication and is involved in the priming of DNA elongation (By similarity).
What are the official names of this protein?
DNA terminal protein, Protein P8.
What is the protein family that this protein belongs to?
Belongs to the tectivirus DNA terminal protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: GMHA_BUCAP
Sequence: MYKKIISSELDAALKILKNFLKNEEQIENIEKAAILIAKSFKNKNKVISCGNGGSHCDAVHFSEELTGLYREKRPGYAAIPISDVGHISAIGNDFGYDQIFSRYIESIGLPNDVLLAISTSGNSINIINAIQTAHRKKMKVIVLTGNDGGQVKHLSDVEICIPYHGYSDRIQEMHIKIIHILILIIEKEMKKIN
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO1C_THEGJ
Sequence: MVAAKTIKTLVWKSELPDNIKEELYNKLIEYNKKYKLKKAEVEAIIEDAVNEYRKALVEPGEPIGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPVMTVFLDEEHRYDLEKAREVARRIEGTTIENLAREMSIDILNFEFIVEIDPERLEKSGLDMERILKKLSGSFKSAEFEAEGYSLIVRPKKVTKLSDLRKLAEKVKKHRLKGLSGVGKTIIRKEGDEYVIYTEGSNFKQVLKVPGVDPTRTRTNNIWEIADVLGIEAARNAIIEEIVNTMREQGLEVDIRHIMLVADMMTLDGVIRPIGRHGIVGEKSSVLARAAFEITTQHLFEAAERGEVDPLNGVVENVLIGQPVPVGTGIVKLTMNLPLRPQRE
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Forms part of the jaw domain.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo1C, DNA-directed RNA polymerase subunit A''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF1_RHOP5
Sequence: MIELLSAAETWVAVGFAILMVVFVYFGVHRTVLNALDNRRDRIKAELDEASRLKEEAAKLLADYKARAASAEREAEAIIASAKDEAERIAAEAKAKLEDFVARRTKTAEGKIAMAEAQAIADVRAAAANAAVAAASSILSQSVKGSVADELIGKGIAEVRSKLN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 1, ATP synthase F(0) sector subunit b 1, ATPase subunit I 1, F-type ATPase subunit b 1, F-ATPase subunit b 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RPOC_CORDI
Sequence: MIDVNFFDELRIGLATADDIRRWSKGEVKKPETINYRTLKPEKDGLFCERIFGPTRDWECACGKYKRVRYKGIICERCGVEVTKSKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAPKDLERIIYFAANIITSVDDEARHADQTTLEAEMLLEKKDVEADMESEIAERAAKLEEDLAELEAAGAKADARNKVKKAAEKEMQHIRERAEREIDRLEEIWQTFIKLAPKQMIIDETIYEELVDRYEDYFTGGMGAEAIQTLIRNFDLDSEAEELREIINNGKGQKKMRALKRLKVVAAFQRSGNDPAGMVLDCIPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRMIELGAPEIIVNNEKRMLQESVDALFDNGRRGRPVTGPGNRPLKSLSDLLKGKQGRFRQNLLGKRVDYSGRSVIIVGPQLKLHECGLPKLMALELFKPFVMKRLVENDYAQNIKSAKRMVERQRPEVWDVLEEAISEHPVMLNRAPTLHRLGIQAFEPKLVEGKAIQLHPLACEAFNADFDGDQMAVHLPLSAEAQAEARILMLASNNILSPASGKPLAMPRLDMVTGLYYLTMDKNENEIGGQGAYASATEEGPAQGVYSSYAEAIMARDRGVLGLQAKIKVRISHLRPPVDIEAEQFPEGWNKGDVWLADTTLGRIMFNELLPWNYPYLEGVMVRKGGGTGKIMLGDVINDLAATYPMITVAQTMDKMKDAGFYWATRSGVTITMSDVLVLPNKEEILDRYEAEARKIERKYWEQGALTERERYDRLVELWKDATDEVGNAVEKLYPDDNPIPMIVKSGAAGNMRQIWTLAGMKGMVVNSKGDYITRPIKTSFREGLSVLEYFNNSHGSRKGLADTALRTADSGYLTRRLVDVAQDVIVREDDCGTKQGIRVPVAVEVKDAEGNVTGYTGHSLIETSVAGRVAATAVKDAEGNVMVEPGENLTDQLIDELIAAGVKEVKVRSVLTCQTPTGVCAKCYGKSMATGKLVDIGEAVGIVAAQSIGEPGTQLTMRTFHQGGVGGDITGGLPRVQELFEARVPKNRAPIASVAGTVHLDDEGNFYTLTINPDDGSDVVVYEKLSKRQGLATVRVPMESNPGAMIERTLAEGDHVEVGDRLLRGPADPHDVLEVLGRRGVEQHLVDEVQDVYRAQGVAIHDKHIEIIIRQMLRRGTVIESGSTEFLPGTLVDLSEAKAANAEALANGGQPAELRSEIMGITKASLATESWLSAASFQETTRVLTDAAINKRSDKLIGLKENVIIGKLIPAGTGISRYRNISVKPTEAARNAAYSIPTYGDSIYGDDGYGEFTGASVPLDEAYDL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: HRH1_PANTR
Sequence: MSLPNSSCLLEDKMCEGNKTTMASPQLMPLVVVLSTICLVTVGLNLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMNILYLLMSKWSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLKYRTKTRASATILGAWFLSFLWVIPILGWNHFMQQTSVRREDKCETDFYDVTWFKVMTAIINFYLPTLLMLWFYAKIYKAVRQHCQHRELINGSLPSFSEIKLRPENPKGDAKKPGKESPWEVLKRKPKDAGGGSVLKSPSQTXKEMKSPVVFSQEDDREVDKLHCFPLDIVPMQTAAEGSSRDYVAVNQSHGQLKTDEQGLNTHGASEISEDQMLGDSQSFSRTDSDTTTETAPGKGKLRSGSNTGLDYIKFTWKRLRSHSRQYVSGLHMNRERKAAKQLGFIMAAFILCWIPYFIFFMVIAFCKNCCNEHLHMFTIWLGYINSTLNPLIYPLCNENFKKTFKRILHIRS
What is the function of this protein?
In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.
What are the official names of this protein?
Histamine H1 receptor, H1R, HH1R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CLV2_ARATH
Sequence: MIKIADFTLFFFIFVFSPSLPLAQSQLPDLDPQDKASLLIFRVSIHDLNRSLSTWYGSSCSNWTGLACQNPTGKVLSLTLSGLNLSSQIHPSLCKLSSLQSLDLSHNNFSGNIPSCFGSLRNLRTLNLSRNRFVGSIPATFVSLKELREVVLSENRDLGGVVPHWFGNFSMNLERVDFSFCSFVGELPESLLYLKSLKYLNLESNNMTGTLRDFQQPLVVLNLASNQFSGTLPCFYASRPSLSILNIAENSLVGGLPSCLGSLKELSHLNLSFNGFNYEISPRLMFSEKLVMLDLSHNGFSGRLPSRISETTEKLGLVLLDLSHNSFSGDIPLRITELKSLQALRLSHNLLTGDIPARIGNLTYLQVIDLSHNALTGSIPLNIVGCFQLLALMISNNNLSGEIQPELDALDSLKILDISNNHISGEIPLTLAGLKSLEIVDISSNNLSGNLNEAITKWSNLKYLSLARNKFSGTLPSWLFKFDKIQMIDYSSNRFSWFIPDDNLNSTRFKDFQTGGGEGFAEPPGKVEIKISAAVVAKDELSFSYNLLSMVGIDLSDNLLHGEIPEALFRQKNIEYLNLSYNFLEGQLPRLEKLPRLKALDLSHNSLSGQVIGNISAPPGLTLLNLSHNCFSGIITEKEGLGKFPGALAGNPELCVETPGSKCDPANIDASQEEIYQNELVEGPISIWIFCLSAFISFDFGVLGIFCSARARSYILQTKA
What is the function of this protein?
Involved in the perception of CLV3 and CLV3-like (CLE) peptides, that act as extracellular signals regulating meristems maintenance.  Required for the sensing of the root CLE peptides (e. g.  CLE8, CLE9/CLE10, CLE11, CLE13, CLE14, CLE16, CLE17, CLE18, CLE20, CLE21, CLE25, CLE26, CLE40, CLE41/CLE44 and CLE45), which involves also CRN and leads to root growth regulation, mostly in the phloem and protophloem (PubMed:28607033).  Involved in controlling the stem cell population size in shoot and root apical meristems, and during organ development.  Promotes the formation of CLV1 multimers.  In complex with CRN, perceives secreted CLV3-like effector proteins from plant-parasitic cyst nematodes as ligand mimics of the plant CLE signaling pathway (PubMed:21265896, PubMed:21750229).  This recognition is required for proper feeding structure (syncytium) development and ultimately successful nematode infection (PubMed:21265896, PubMed:21750229).  CLE14 perception by CLV2/CRN complex triggers root meristem differentiation (PubMed:20697738, PubMed:28586647).
What are the official names of this protein?
Receptor-like protein CLAVATA2, Receptor-like protein 10, AtRLP10.
What is the protein family that this protein belongs to?
Belongs to the RLP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Requires CRN for export from the endoplasmic reticulum and localization to the plasma membrane.
Protein: DHSD_NATPH
Sequence: MSQSYDRGLVEDFGRWQEFSAGMWAWIFHKFTGWVLIGYLFTHVAVLSTATVDAATYTQTLQGLESLLVVRFLEVGLLAVAVFHILNGIRLLFVDLGVGLEAQDKAFYAALIVTAAITVASIPTFLMGAF
What is the function of this protein?
Membrane-anchoring subunit of succinate dehydrogenase (SDH).
What are the official names of this protein?
Succinate dehydrogenase hydrophobic membrane anchor subunit.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YICR_ECO55
Sequence: MKNNSQLLMPREKMLKFGISALTDVELLALFLRTGTRGKDVLTLAKEMLENFGSLYGLLTSEYEQFSGVHGIGVAKFAQLKGIAELARRYYNVRMREESPLLSPEMTREFLQSQLTGEEREIFMVIFLDSQHRVITHSRLFSGTLNHVEVHPREIIREAIKINASALILAHNHPSGCAEPSKADKLITERIIKSCQFMDLRVLDHIVIGRGEYVSFAERGWI
What are the official names of this protein?
UPF0758 protein YicR.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family. YicR subfamily.
Protein: RL31_BART1
Sequence: MKANIHPNYHKITVVMTDGTQYTTRSTWGKEGDTLNLDIDPRTHPAWTGGSQTLVDRGGRLSKFKNRFGNIGM
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: MSAB2_STRPN
Sequence: MHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYELINQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDKDLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAYPVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEPLFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGPQDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA/MsrB 2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
Protein: STOM_MOUSE
Sequence: MSDKRQSSHVQSQRIPESFRENSKTELGACGWILVAASFFFVIITFPISIWICIKIVKEYERVIIFRLGRILQGGAKGPGLFFILPCTDSLIKVDMRTISFDIPPQEVLTKDSVTISVDGVVYYRVQNATLAVANITNADSATRLLAQTTLRNALGTKNLSQILSDREEIAHHMQSTLDDATDDWGIKVERVEIKDVKLPVQLQRAMAAEAEAAREARAKVIAAEGEMNASRALKEASMVITESPAALQLRYLQTLTTIAAEKNSTIVFPLPVDMLQGIMGSNH
What is the function of this protein?
Regulates ion channel activity and transmembrane ion transport.  Regulates ASIC2 and ASIC3 channel activity.
What are the official names of this protein?
Stomatin, Erythrocyte band 7 integral membrane protein, Erythrocyte membrane protein band 7.2, Protein 7.2b.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor; Cytoplasmic side. Membrane raft. Melanosome. Cytoplasmic vesicle. Note=Localizes to juxtanuclear structure probably derived from the Golgi apparatus. Colocalizes with cortical actin microfilaments at small plasma membrane protrusions. Associates with alpha-granular lipid rafts. Translocates from the alpha-granular lipid rafts to the cell membrane on thrombin activation and selectively enriched in released microvesicles. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Protein: SDA_BACSU
Sequence: MNWVPSMRKLSDELLIESYFKATEMNLNRDFIELIENEIKRRSLGHIISVSS
What is the function of this protein?
Mediates a developmental checkpoint inhibiting initiation of sporulation (by preventing phosphorylation of spo0A) in response to defects in the replication initiation machinery.  Inhibits autophosphorylation of the histidine protein kinase KinA, forming a molecular barricade that prevents productive interaction between the ATP-binding site in the catalytic domain and the phosphorylatable His in the phosphotransfer domain of KinA.  Probably also inhibits the activity of KinB, but has relatively little effect on KinC.  Has at least one target in vivo in addition to KinA as sda does not require KinA to inhibit sporulation.
What are the official names of this protein?
Sporulation inhibitor sda, Histidine kinase KinA inhibitor.