PharMolix/UniProtQA huggingface dataset:
Protein: ASIP_MACHE
Sequence: MDVTRLLLATLLVFLCFFTAYSHPPPEEKLRDDRSLRSNSSVNLLDFPSVSIVALNKNSKQISRKEAEKKRSSKKEASMKKVARPRTPLSAPCVATRDSCKPPAPACCDPCAFCQCRFFRSACSCRVLSLNC
What is the function of this protein?
Involved in the regulation of melanogenesis.  The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).
What are the official names of this protein?
Agouti-signaling protein, ASP, Agouti switch protein.
What are the subcellular locations of this protein?
Secreted.
Protein: ERG10_SCHPO
Sequence: MVNTEVYIVSAVRTPMGSFGGSFASLPATKLGSIAIKGALERVNIKPSDVDEVFMGNVVSANLGQNPARQCALGAGLPRSIVCTTVNKVCASGMKATILGAQTIMTGNAEIVVAGGTESMSNAPYYAPKNRFGAKYGNVELVDGLLRDGLSDAYDGLPMGNAAELCAEEHSIDRASQDAFAISSYKRAQNAQATKAFEQEIVPVEVPVGRGKPNKLVTEDEEPKNLNEDKLKSVRAVFKSNGTVTAANASTLNDGASALVLMSAAKVKELGLKPLAKIIGWGEAAQDPERFTTSPSLAIPKALKHAGIEASQVDYYEINEAFSVVAVANTKILGLDPERVNINGGGVAMGHPLGSSGSRIICTLAYILAQKDAKIGVAAVCNGGGGASSIVIERV
What is the function of this protein?
Acetyl-CoA acetyltransferase; part of the first module of ergosterol biosynthesis pathway that includes the early steps of the pathway, conserved across all eukaryotes, and which results in the formation of mevalonate from acetyl-coenzyme A (acetyl-CoA) (By similarity).  Erg10 catalyzes the formation of acetoacetyl-CoA from acetyl-CoA (By similarity).  The first module starts with the action of the cytosolic acetyl-CoA acetyltransferase eg10 that catalyzes the formation of acetoacetyl-CoA.  The hydroxymethylglutaryl-CoA synthases erg13 then condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.  The rate-limiting step of the early module is the reduction to mevalonate by the 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductases hcs1 (Probable).
What are the official names of this protein?
Acetyl-CoA acetyltransferase, Acetoacetyl-CoA thiolase, Ergosterol biosynthesis protein 10.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U7B11_ARATH
Sequence: MGQKIHAFMFPWFAFGHMTPYLHLGNKLAEKGHRVTFLLPKKAQKQLEHQNLFPHGIVFHPLVIPHVDGLPAGAETASDIPISLVKFLSIAMDLTRDQIEAAIGALRPDLILFDLAHWVPEMAKALKVKSMLYNVMSATSIAHDLVPGGELGVAPPGYPSSKALYREHDAHALLTFSGFYKRFYHRFTTGLMNCDFISIRTCEEIEGKFCDYIESQYKKKVLLTGPMLPEPDKSKPLEDQWSHWLSGFGQGSVVFCALGSQTILEKNQFQELCLGIELTGLPFLVAVKPPKGANTIHEALPEGFEERVKGRGIVWGEWVQQPSWQPLILAHPSVGCFVSHCGFGSMWESLMSDCQIVFIPVLNDQVLTTRVMTEELEVSVEVQREETGWFSKENLSGAIMSLMDQDSEIGNQVRRNHSKLKETLASPGLLTGYTDKFVDTLENLVNEQGYIS
What are the official names of this protein?
UDP-glycosyltransferase 79B11.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: RS2_MYCS2
Sequence: MAVVTMKQLLDSGAHFGHQTRRWNPKMKRFIFTDRNGIYIIDLQQTLTYIDKAYEFVKETVAHGGTVLFVGTKKQAQESIAEEATRVGMPYVNQRWLGGMLTNFSTVHKRLQRLKELEAMEQTGGFEGRTKKEILMLTREKNKLERSLGGIRDMQKVPSAVWVVDTNKEHIAVGEARKLGIPVIAILDTNCDPDVVDYPIPGNDDAIRSAALLTKVIASAVAEGLQARAGQGSGEKPAEGAEPLAEWEQELLAGATAGAADASAEGAAAPESSTDAS
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: YIDD_ACIBT
Sequence: MVRILRWFIRLYQIAISPLLGPRCRYIPTCSQYALEALQTHGAIKGVWLSSKRICRCHPWGGSGYDPVPPKAIRFISFHQIDSQTHHVAVPFRDRLMKQNLSNHLG
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HBA_ONDZI
Sequence: VLSGEDKNNIKTAWGKIGGHAAEYGAEALERMFVVYPTTKTYFPHFDVSHGSGQVKAHGKKVADALTTAVGHLDDLPGALSALSDLHAHKLRVDPVNFKLLSHCLLVTLANHIPADFTPAVHASLDKFLASVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: ALR_BURM7
Sequence: MPRPISATIHTAALANNLSVVRRHAAQSKVWAIVKANAYGHGLARVFPGLRGTDGFGLLDLDEAVKLRELGWAGPILLLEGFFRSTDIDVIDRYSLTTAVHNDEQMRMLETARLSKPVNVQLKMNSGMNRLGYTPEKYRAAWERARACPGIGQITLMTHFSDADGERGVAEQMATFERGAQGIAGARSFANSAAVLWHPSAHFDWVRPGIMLYGASPSGRAADIADRGLKPTMTLASELIAVQTLAKGQAVGYGSMFVAEDTMRIGVVACGYADGYPRIAPEGTPVVVDGVRTRIVGRVSMDMLTVDLTPVPQAGVGARVELWGETLPIDDVAARCMTVGYELMCAVAPRVPVRAE
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: FSHR_HORSE
Sequence: MALLLVSLLAFLSLGSGCHHRVCHCSNRVFLCQESKVTEIPSDLPRNALELRFVLTKLRVIPKGAFSGFGDLEKIEISQNDVLEVIEANVFSNLPKLHEIRIEKANNLLYIDHDAFQNLPNLQYLLISNTGIKHLPAVHKIQSLQKVLLDIQDNINIHTVERNSFMGLSFESTILRLSKNGIQEIHNCAFNGTQLDELNLSYNNNLEELPNDVFQGASGPVILDISGTRIHSLPNYGLENLKKLRARSTYNLKKLPSLEKFVALMEANLTYPSHCCAFANWRRQTSELQTTCNKSILRQEVDMTQARGERVSLAEDDESSYPKGFDMMYSEFEYDLCNEVVDVTCSPKPDAFNPCEDIMGYDILRVLIWFISILAITGNIIVLVILITSQYKLTVPRFLMCNLAFADLCIGIYLLLIASVDIHTKSQYHNYAIDWQTGAGCDAAGFFTVFASELSVYTLTAITLERWHTITHAMQLECKVQLRHAASVMLVGWIFAFAVALLPIFGISTYMKVSICLPMDIDSPLSQLYVMSLLVLNVLAFVVICGCYIHIYLTVRNPNIVSSSSDTKIAKRMAILIFTDFLCMAPISFFAISASLKVPLITVSKSKILLVLFYPINSCANPFLYAIFTKNFRRDFFILLSKFGCYEMQAQLYRTETSSTAHISHPRNGHCPPTPRVINGANCTLVPLSHLAQN
What is the function of this protein?
G protein-coupled receptor for follitropin, the follicle-stimulating hormone.  Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
What are the official names of this protein?
Follicle-stimulating hormone receptor, FSH-R, Follitropin receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y3127_BACC3
Sequence: MKIYVDADACPVKDVIIFEATKAKIPVTLVTSFSHYSNAEQPKSVETIYVDSGADAADYRIMQLAQKEDLIVTQDYGLASLALAKGCIVLHHKGYKYTNDNIEQLLQTRYLSAMVRKSGKRTKGPKPFTAEDKEKFRALFKSMIAL
What are the official names of this protein?
UPF0178 protein BCA_3127.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: CPG9_CAEEL
Sequence: MHLWQLVLLVILFFGAAFGADLEGSGSGDVSTDAKEAILNAQTLLDAVSSDGSGADVEASGEDVQTFFF
What are the official names of this protein?
Chondroitin proteoglycan 9.
Protein: PU60B_DANRE
Sequence: MENGQGTGSKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAVTMGFGDPLSSLQSVAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPGSIGQAQPIIEQLAEEARAYNRIYVASIHPDLSDDDIKSVFEAFGKIKSCMLAREPTTGKHKGFGFIEYEKPQSSLDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPTTPGGLPPAAAVAAAAATAKITAQEAVAGTVLSSLASPAHILSQQMGLPQAVLAAQAPGIITGLSTTKTVFHLVGLVNPVLASPPVTAPASMGTPTSAVQLHTEVKREEDSRRTAEDHSAPVGNGQDSELERLSVSASAGRQAAIQSKSTVMVLRNMVGPEDIDDDLEGEVMEECGKYGAVNRVIIYQERQGEEDDAEIIVKIFVEFSDAGEMNKAIQALNNRWFAGRKVVAELYDQDRFNSSDLTA
What is the function of this protein?
DNA- and RNA-binding protein, involved in transcription repression and pre-mRNA splicing.
What are the official names of this protein?
Poly(U)-binding-splicing factor PUF60-B.
What is the protein family that this protein belongs to?
Belongs to the RRM half pint family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NADA_ECOUT
Sequence: MSVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIDHLDSLGEKIIWAPDKHLGCYVQKQTGADILCWQGACIVHDEFKTQALTRLQEEYPDAAILVHPESPQAIVEMADAVGSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWMAMNGLQAIAEALELEGSNHEVYVDERLLERALVPLNRMLDFAATLRG
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPT3_ORYSJ
Sequence: MQRAAAASRATAWSTARHGAARVTASASFSGGGGIVAGAALPLRVRGGQLMSLPLLSGGRAVTARVAAAEAPLPADDADAAAGRERGALAETAQLGAMIVAWYLLNIYFNIYNKQVLQPLPFPYTITAFQLAFGSFVIFLMWALKLHPAPRISISQLAKIAPLAAGHMLGTVFTNMSLSKVAVSFTHTIKASEPFFTVLLSAFFLGETPSLLVLGSLVPIVGGVALASLTELSFNWIGFWSAMASNLLYQSRNVLSKKLLGGEEEALDDINLFSILTILSFLLSLPLMLFSEGVKFSPGYLRSTGLNLQELCVRAALAGFCFHGYQKLSYLILARVSPVTHSVANCVKRVVVIVASVLFFRTPISPVNALGTGVALGGVFLYSRLKRTKPKNA
What is the function of this protein?
Phosphoenolpyruvate/phosphate translocator that transports phosphoenolpyruvate (PEP) and dihydroxyacetone phosphate.
What are the official names of this protein?
Phosphoenolpyruvate/phosphate translocator 3, chloroplastic, OsPPT3.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. PPT (TC 2.A.7.9) subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: PP6R1_MOUSE
Sequence: MFWKFDLHTSSHLDTLLEKEDLSLPELLDEEDVLQECKVVNRKLLDFLLQPSHLQAMVAWVTQEPPASGEERLRYKYPSVACEILTSDVPQINDALGADESLLNRLYGFLQSGDSLNPLLASFFSKVMGILINRKTDQLVSFLRKKDDFVDLLLRHIGTSAIMDLLLRLLTCVERPQLRQDVFNWLNEEKIVQRLIEQIHPSKDDNQHSNASQSLCDIIRLSREQMIQGQDSPEPDQLLATLEKQETIEQLLSNMFEGEQCQSVIVSGIQVLLTLLEPRRPRSDSVTMNNFFSSVDGQLELLAQGALDDALSSMGALHALRPRLDRFHQLLLEPPKLEPLQMTWGSLAPPLGNTRLHVVKLLASALSANAAALTQELLVLDVPNTLLDLFFHYVFNNFLHAQVEVCVSAMLSSGPPPDSSSETPVPNPIVKHLLQHCRLVERILASWEENDRVQSGGGPRKGYMGHLTRVANAVVQNAEQGPNAEQLGQLLKELPEEQQQRWEAFVSGPLAETNKKNTVDLVNTHHLHSSSDDEDDRLKEFNFPEEAVLQQAFMDFQMQRMTSAFIDHFGFNDEEFGEQEESVNAPFDKTANITFSLNADDENPNANLLEICYKDRIQQFDDEEEEEEEGQGSAESDGEYGAWQGSQPVRASQASQPPGVRSGGSTDSEEEDEEEDEEEDEGAEQAACGRTSPSSFPSPSTQPPGPSWTATFDTVPMDAPTGPPVSKEADMSSIQIPSSPPAHGSPQLRSQDPTHPSAPQEVTDSSKVAEPLAPCQALVSVADVQATLHGMRSAPSSLDSATRDPSTSVPDFKAHQSPQTMEGKRSPEHLGLPQSQSALEMPNGSTPGGPISSGSQ
What is the function of this protein?
Regulatory subunit of protein phosphatase 6 (PP6).  May function as a scaffolding PP6 subunit.  Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 6 regulatory subunit 1, SAPS domain family member 1.
What is the protein family that this protein belongs to?
Belongs to the SAPS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAN1_ORYSJ
Sequence: MALPNQQTVDYPSFKLVIVGDGGTGKTTFVKRHLTGEFEKKYEPTIGVEVHPLDFFTNCGKIRFYCWDTAGQEKFGGLRDGYYIHGQCAIIMFDVTSRLTYKNVPTWHRDLCRVCENIPIVLCGNKVDVKNRQVKAKQVTFHRKKNLQYYEVSAKSNYNFEKPFLYLARKLAGDGNLHFVETPALAPPDVTIDLAAQQQHEAELAAAAAQPLPDDDDDLIE
What is the function of this protein?
GTP-binding protein involved in nucleocytoplasmic transport.  Required for the import of protein into the nucleus and also for RNA export.  Involved in chromatin condensation and control of cell cycle (By similarity).
What are the official names of this protein?
GTP-binding nuclear protein Ran-1, OsRan1, Ras-related nuclear protein 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ran family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYB_LEPTI
Sequence: MTNIRKTHPLLKIVNHSLIDLPAPSNISAWWNFGSLLGLCLMIQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWLIRYLHANGASMFFICLYMHVGRGIYYGSYTYLETWNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALVMIHLLFLHETGSNNPSGIPSDSDKIPFHPYYTIKDLLGFLVLILLLMLLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILILAIIPFLHMSKQRSMMFRPISQVLFWILVADLLTLTWIGGQPVEHPFITIGQVASILYFSIILILMPLASLIENKILKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GNTU_ECOLI
Sequence: MTTLTLVLTAVGSVLLLLFLVMKARMHAFLALMVVSMGAGLFSGMPLDKIAATMEKGMGGTLGFLAVVVALGAMFGKILHETGAVDQIAVKMLKSFGHSRAHYAIGLAGLVCALPLFFEVAIVLLISVAFSMARHTGTNLVKLVIPLFAGVAAAAAFLVPGPAPMLLASQMNADFGWMILIGLCAAIPGMIIAGPLWGNFISRYVELHIPDDISEPHLGEGKMPSFGFSLSLILLPLVLVGLKTIAARFVPEGSTAYEWFEFIGHPFTAILVACLVAIYGLAMRQGMPKDKVMEICGHALQPAGIILLVIGAGGVFKQVLVDSGVGPALGEALTGMGLPIAITCFVLAAAVRIIQGSATVACLTAVGLVMPVIEQLNYSGAQMAALSICIAGGSIVVSHVNDAGFWLFGKFTGATEAETLKTWTMMETILGTVGAIVGMIAFQLLS
What is the function of this protein?
Part of the gluconate utilization system Gnt-I; low-affinity intake of gluconate.
What are the official names of this protein?
Low-affinity gluconate transporter, Gluconate permease, Gnt-I system.
What is the protein family that this protein belongs to?
Belongs to the GntP permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPLC_STAA1
Sequence: MNKNIVIKSMAALAILTSVTGINAAVVEETQQIANAEKNVTQVKDTNNFPYNGVVSFKDATGFVIGKNTIITNKHVSKDYKVGDRITAHPNGDKGNGGIYKIKSISDYPGDEDISVMNIEEQAVERGPKGFNFNENVQAFNFAKDAKVDDKIKVIGYPLPAQNSFKQFESTGTIKRIKDNILNFDAYIEPGNSGSPVLNSNNEVIGVVYGGIGKIGSEYNGAVYFTPQIKDFIQKHIEQ
What are the official names of this protein?
Serine protease SplC.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: MDCB_STUS1
Sequence: MSALIARQAPSAAERLADLAVQALVDEADLSPKPGLVDRRGSGAHSDLHLGLMHASAQSLWPAFAAMADAARSEGRVSQALRETLGQLGRDGEAEMLRVTAGVNTHRGAIWALGLLSAAAMLESGASAGGIAASAAALARLDDPAAPHNPDSHGARVCRRYGVLGAREQAQHGFPAVIEHGLPQLLASRRAGAGEQNARLDALLAIMSSLTDTCVLHRAGLEGLTRMQAGARAVLEAGGCASLAGRRRLRALEGEMLSLRASPGGAADLLAATLFLDRLTPAASAPIGSY
What is the function of this protein?
Involved in the formation of 2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase.
What are the official names of this protein?
Probable 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase, 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the CitG/MdcB family.
Protein: HIS8_WOLSU
Sequence: MQFNPTLDSIKTYEAGKPIELVVREYGIKPQNVIKLASNENPFGASPKVIEAIAKEAVNAHRYPDDSMFELKEGLAGRFGVKSENVIIGSGSDQILEMAVHAKCNASSKVLMSKTTFAMYDVYSRQVGARILRTPSDQHHLGEFWEIYQKERPEILFLCLPNNPLGECLDREEVYDFLQKIDDETLVIVDGAYQEYAAFKDSQKRIDPKDLIERFPSSIFLGTFSKAFGLGGMRVGYGIAQPSIIQALMKMRAPFNITTLSLKAAIEALKESAYVEETIKENFKEMRRYEEFALAQGIDFIPSYTNFITLLLKNRVDSSEFSQWLLERGLIVRNLKSYGINAIRITIGRSLENDRCFELMQEYLHQF
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RNH3_STRPZ
Sequence: MNTLVLKIDAVLSKHLKKQLASYTISSQNTYVAFAAKKNGVTVLLYKSGKLVLQGNGANALAQELNLPVAKTVFEASNNSQDIPIIGSDEVGNGSYFGGIAVVASFVDPKDHSFLKKLGVDDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGKSKPYNAISIKVALHNQAIFLLLQKGIQPKQIVIDAFTSQSNYEKHLKKEKNHFPNPLTFQEKAESHYLAVAVSSIIARNLFLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYGMSSLEYSAKLHFANTHKAQALLTK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STAD3_ORYSJ
Sequence: MSLTGCLPPRPPCSMRRRTSGGGASVSPVVAMASTAGVGGIGNPTPRGKKPFAPWREVPPQVTHTLPPEKKEVFDSLEGWAADTILPYLKPVEESWQPQDHLPDPRSPSFGDEVAALRERAAGLPDDHLVCLVGDMVTEEALPTYQTMLNTMDGGVRDETGAGGSAWAVWTRAWAAEENRHGDLMNKYLYLTGRVDMRQVEKTIQYLIGSGMDPRTENDPYMGFIYTTFQERATSISHGNTARHAGRHGDAALARVCGTVAADEKRHEAAYAAIVAKLFEVDPDYTVRAFARMMRRKVAMPARLMYDGADDRLFARFAAVAQRLGVYTAADYAGIIEFLVARWGVPGLAAGLSGEGRRAQDFVCSLGPRFRRMEERAQEAAKRAPPAAAAPFSWIHGRQVQL
What is the function of this protein?
Introduces a cis double bond in the acyl chain of an acyl-[acyl-carrier protein].
What are the official names of this protein?
Acyl-[acyl-carrier-protein] desaturase 3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PDXT_FRATO
Sequence: MTQKVGVLAIQGGYQKHADMFKSLGVEVKLVKFNNDFDSIDRLVIPGGESTTLLNLLNKHQIFDKLYNFCSSKPVFGTCAGSIILSKGEGYLNLLDLEVQRNAYGRQVDSFVADISFNDKNITGVFIRAPKFIVVGNQVDILSKYQNSPVLLRQANILVSSFHPELTQDPTVHEYFLAM
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: DNLJ_PORG3
Sequence: MEKIVPPAVRIEELRRILREHEYRYYVLSSPTIDDFEYDAMMKQLEELEREYPEWDSPDSPTHRVGSDKTEGFASVRHDRPMLSLSNTYNYDEIGDFYRRVSEGLQGAPFEIVAELKFDGLSISLIYEDGMLVRAVTRGDGIMGDDVTANVRTIRSVPLRLRGDDYPRMLEVRGEILLPFKEFDRINAQREAEGEPLFANPRNAASGTIKQLDPHIVAGRNLDAYFYYLYSDEPLAENHYDRLMQARQWGFKVSDAVTLCCSKEDVYAFIDRFDTERLTLPVATDGIVLKVNAPAQQDLLGFTAKSPRWAIAYKYQAERVRTRLQHVSYQVGRTGAVTPVANLDPVLISGTVVRRASLHNADFIAEKDLHEGDFVYVEKGGEIIPKIVGVDTDARSIDGRPIVFTVLCPDCATPLVREQGEAAYYCPNAEGCPQQQKGRLEHYCGRKAADINIGPETIELLYSRNMIRNVADFYALTEEQLLTLPGFKKRAAAKLLDSIEASKARPYQAILFGLGIRFVGETVAKKLAAVYPSIDALAAATSEELVQIDEIGERIAAAVLHFFSLRQNRELIERLRLAGVSLEAETVSVPVSARLAGKTVVISGTFEKYSRDEYKAMVEDNGGRMAGSVSSKTSFILAGSDMGPSKREKAEKLGVRLMSEEEFLRLIEE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: Y4477_BURCM
Sequence: MNDFSRSISDLTPERVTTAFDLAGHTTARSLGVAQGIVVRSRSIVGSFGAGLQTLFGGNITLYTSLCEKARQQAFDKMLADARKLGANAVVAMRYDSTEIGSGITEVICYGTAVQVTRDAGA
What are the official names of this protein?
UPF0145 protein Bamb_4477.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: KAX3D_MESEU
Sequence: VGINVKCKHSGQCLKPCKDAGMRFGKCMNGKCDCTPK
What is the function of this protein?
Blocks voltage-gated potassium channels Kv1. 1/KCNA1 (IC(50)=203. 15 pM), Kv1. 2/KCNA2 (IC(50)=8. 92 nM) from rat and human Kv1. 3 KCNA3/KCNA3 (IC(50)=171 pM) potently.  At 2 uM, also blocks Shaker IR and has a moderate effect on rat Kv1. 6/KCNA6.
What are the official names of this protein?
Potassium channel toxin alpha-KTx 3.13, MeuKTx.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 03 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LYM4B_SALSA
Sequence: MAACTAQVLSLYRKLMKESNKFPSYNYRTYALRRVQDAFRANRSVEDPKMVEQLLNQGRDNLDMIRRQVAIGKMYPTQKTIVEG
What are the official names of this protein?
LYR motif-containing protein 4B.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family.
Protein: SYFA_STAAT
Sequence: MSEQQTMSELKQQALVDINEANDERALQEVKVKYLGKKGSVSGLMKLMKDLPNEDKPAFGQKVNELRQTIQNELDERQQMLVKEKLNKQLAEETIDVSLPGRHIEIGSKHPLTRTIEEIEDLFLGLGYEIVNGYEVEQDHYNFEMLNLPKSHPARDMQDSFYITDEILLRTHTSPVQARTMESRHGQGPVKIICPGKVYRRDSDDATHSHQFTQIEGLVVDKNVKMSDLKGTLELLAKKLFGADREIRLRPSYFPFTEPSVEVDVSCFKCKGKGCNVCKHTGWIEILGAGMVHPNVLEMAGFDSSEYSGFAFGMGPDRIAMLKYGIEDIRHFYTNDVRFLDQFKAVEDRGDM
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ST6B1_GORGO
Sequence: MADKSKFTEYIDKALEKSKETALSHLFFTYQGIAYPITMCTSETFQALDTFEARHDDIVLASYPKCGSNWILHIVSELIYAVSKKKYKYPEFPVLECGDSEKYQRMKGFPSPRILATHLHYDKLPGSIFKNKAKILVIFRNPTDTAVSFFHFHNDVPDIPSYGSWDELFRQFMKGQVSWGSYFDFAINWNKHLDGDNVKFILYEDLKENLAAGIKQIPEFLGFFLTGEQIQTISVQSTFQAMRAKSQDTHGAVGPFLFRKGEVGDWKNLFSEIQNQEMDEKFKECLAGTSLGAKLKYESYCQG
What is the function of this protein?
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of thyroxine.  Involved in the metabolism of thyroxine (By similarity).
What are the official names of this protein?
Sulfotransferase 6B1, ST6B1, Thyroxine sulfotransferase.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: SKP_PECAS
Sequence: MKKWLCAAGLGLVLAASASVQAADKIAVVNVSSIFQQLPQRESVGKQLENEFKGRASELQSMENDLQGKMQKLQRDGSTMKASDRSKMEKDVMAQREQFSTKAQAFEQDNRRRQTEERNKILSRIQDAVKAVATKEGYDVVIDANAVAYVANAKDITADVLKQVK
What is the function of this protein?
Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm.
What are the official names of this protein?
Chaperone protein Skp.
What is the protein family that this protein belongs to?
Belongs to the Skp family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ASIP_LEOCY
Sequence: MDVTXLLLATLLVFLCCFAAYSHLPPEEKLRDDRSLRSNSSVNLLDLPSVSIVALNKKSKKISRKEAENKRSSKKEASKQKVARPRTPLSVPCVSTRGSCKPPAPACCHPCASCQCRFFRSACSCRVINVNC
What is the function of this protein?
Involved in the regulation of melanogenesis.  The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).
What are the official names of this protein?
Agouti-signaling protein, ASP, Agouti switch protein.
What are the subcellular locations of this protein?
Secreted.