PharMolix/UniProtQA huggingface dataset:
Protein: Y757_AQUAE
Sequence: MKAESVSQWILVILFATLLFFAFTGIFVSTLLVVLTPEGFAFLLGFLGALVFANKLLFGYGSFVITAEAFLTNKEIDRRELAKKTNEPVERTENLSIPALLALWLAGLDYYRYAYYGIFTLMLIIMLLSKFDLLGALTIGNYFEGAFWGAAVITLFVFALEITANYLMARINEEVSLNG
What are the official names of this protein?
Uncharacterized protein aq_757.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SWP12_ENCCU
Sequence: MDKETVKDIQRSIAMKLNRVEYTEVPLIEGYSEAEDCYKRFRDSLKKISDSITWLMTYEYGGSKMKSLYSKMTMITSTSRIGQFKNYDIYEANGLIGLEFSKIGVASSLSDTGKKYSKAYMDISRYKLEMNSRLEQQLKKISDLRDHSNAIDKKRKKVSNIRYDLEMEKKSKEPKTPSMVSRENDMERTFKETSKEALKEMERFIGNDGVSGVLQKVAEAHRMFTEKSAKALEEVK
What are the official names of this protein?
Spore wall protein 12.
What is the protein family that this protein belongs to?
Belongs to the SWP12 family.
What are the subcellular locations of this protein?
Spore wall.
Protein: NETR_RAT
Sequence: MALARCVLAVILGVLSEVARADPVLHSPLHRPHPSPPRSQHAHYLPSSRRPPRTPRFPLPPRAPAAQRPQLLSTRHTPPTISRRCGAGEPWGNATNLGVPCLHWDEVPPFLERSPPASWAELRGQPHNFCRSPGGAGRPWCFYRNAQGKVDWGYCDCGQGPALPVIRLVGGKSGHEGRVELYHAGQWGTICDDQWDDADAEVICRQLGLSGIAKAWHQAHFGEGSGPILLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCAPLTDGVIRLSGGKSVHEGRLEVYYRGQWGTVCDDGWTEMNTYVACRLLGFKYGKQSSVNHFEGSSRPIWLDDVSCSGKEASFIQCSRRQWGRHDCSHREDVGLTCYPDSDGHRLSPGFPIRLMDGENKREGRVEVFVSGQWGTICDDGWTDKHAAVICRQLGYKGPARARTMAYFGEGKGPIHMDNVKCTGNEKALADCVKQDIGRHNCRHSEDAGVICDYYEKKTSGHGNKETLSSGCGLRLLHRRQKRIIGGNNSLRGAWPWQASLRLKSTHGDGRLLCGATLLSSCWVLTAAHCFKRYGNNSRSYAVRVGDYHTLVPEEFEQEIGVQQIVIHRNYRPDSSDYDIALVRLQGSGEQCARLSTHVLPACLPLWRERPQKTASNCHITGWGDTGRAYSRTLQQAAVPLLPKRFCKERYKGLFTGRMLCAGNLQEDNRVDSCQGDSGGPLMCEKPDETWVVYGVTSWGYGCGIKDTPGVYTRVPAFVPWIKSVTSL
What is the function of this protein?
Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations.
What are the official names of this protein?
Neurotrypsin, Serine protease 12.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: FIBA_PAPHA
Sequence: ADTGEGDFLAEGGGVR
What is the function of this protein?
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.  Fibrin has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen alpha chain.
What are the subcellular locations of this protein?
Secreted.
Protein: RISB_CHLPD
Sequence: MQIKQIEGSLSAKGARFALVVSRFNDFIGQKLVEGALDCLRRHGAEDSEVVIYRCPGAFELPMVAKKAALSGNHDAVIALGVIIRGSTPHFDVIAAEATKGLAQVALDTMIPVAFGVLTTENLEQAIERAGTKAGNKGFDAAMTVIEMVNLYRQF
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: SECE_RICBE
Sequence: MFKEYKIYKFFEQVKQEAYKVVWPTKKELTASTLVVIVAVFVFSLICLVLDYGIHNIIQILLNIGK
What is the function of this protein?
Essential subunit of the Sec protein translocation channel SecYEG.  Clamps together the 2 halves of SecY.  May contact the channel plug during translocation.
What are the official names of this protein?
Protein translocase subunit SecE.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: INUE_PICGU
Sequence: MRAFLALIFLTFVMNVESSRPLMAFTPSHGWMNDPNGQFYDSKNELWHLYYQYNPNDTVWGTPLYWGHATSKDLSTWKDYGATIGPDRDEDGIFSGNIVVDHNNTSGFFNDSIDPRQRVVAIYTYNTEGSQTQHVAYSLDGGYTFEKYEHNPVLDVDNINFRDPKVFWHEPTNQWIMVIALSQQFKIQIYGSIDLTNWSLHSNFTGGLFGFQYECPGLIEVPVEGTDESKWVMFIAINPGSPLGGSSNQYFIGSFDGFEFVPDDSQARLMDYGKDFYAFQTFDNAPKESGVVGLAWASNWQYANLAPTKEWRSSMTLARQMTLASRNMNPETKVLSLLQKPIFGESVVAANKISKRNITGQDEQAVKIHKNSTGTFSFDITFSVDSSKNQTGQLQVISGQNGESIRAGFDPTAGQFFVDRGNTSGLKENPFFTDKTSAYVEPWKHQNDLPVYKMFGVIDGNLIEVFLNDGIATLTNTFFIPGTEGLEYLEIESSSDAIHIVESEVKELKLRATS
What is the function of this protein?
Exo-inulinase involved in utilization of the plant storage polymer inulin, consisting of fructooligosaccharides with a degree of polymerization (DP) value from 2 to 60.  Splits off terminal fructose units successively from the non-reducing end of the inulin molecule.
What are the official names of this protein?
Extracellular exo-inulinase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYH_CAMJR
Sequence: MINALKGMKDLLDKDAYYYEKVIKICEEVAKNYGFTFINTPHLELCTLFKRSVGESSDIVGKEMYEFIDKGENHVCMRPEGTAGVVRAYIEKKLDKNTSVKRWFYYGSMFRYERPQKGRLREFHQFGVESLGIPNVYEDASIILMLVEIFSRLGIDFKLQLNSLGCSQCLPKYRDRLVEFLDSKEGFCEDCLRRKNLNPIRVLDCKNEHCQNLLENAPLLINNLCTSCQKDFETLQQILKDNGVKFELDSKLVRGLDYYSKTAFEFISDEIGAKAAIAGGGRYDRLIEYLGGKSGYGIGFAMGIERIITILEQKEEKIQREGIYLCAMDEIYIQKLLHIATNLRKEYKVLLSYEARKLAKHLENADKNNTEIFLCMGENEAQNESLFYKNLAKKEEKMIKISDLKKVL
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_STAA3
Sequence: MARIAGVDIPREKRVVISLTYIYGIGTSTAQKILEEANVSADTRVKDLTDDELGRIREVVDGYKVEGDLRRETNLNIKRLMEISSYRGIRHRRGLPVRGQKTKNNARTRKGPVKTVANKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: YCLN_BACSU
Sequence: MKLRYLFILLIILAVTSVFIGVEDLSPLDLFDLSKQEASTLFASRLPRLISIVIAGLSMSICGLIMQQISRNKFVSPTTAGTMDWARLGILISLLLFTSASPLIKMLVAFVFALAGNFLFMKILERIKFNDTIFIPLVGLMLGNIVSSIATFIAYKYDLIQNVSSWLQGDFSLVVKGRYELLYLSIPLVIIAYVYADKFTLAGMGESFSVNLGLKYKRVVNIGLIIVSLITSLVILTVGMLPFLGLIIPNIVSIYRGDNLKSSLPHTVLLGAVFVLFCDILGRIIIFPYEISIGLMVGIIGSGIFLFMLLRRKAYA
What is the function of this protein?
Part of the ABC transporter complex YclNOPQ involved in uptake of ferric-petrobactin.  Petrobactin is a photoreactive 3,4-catecholate siderophore produced by many members of the B. cereus group, including B. anthracis.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Petrobactin import system permease protein YclN.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEUC_ACIBT
Sequence: MAGKTLYDKLWDDHVVTQRDDGSCLLYIDRHLLHEVTSPQAFEGLQLAGRQPWRLSANVATPDHNVPTSKKERDQGIAGIEDDTSRIQVQTLDDNCKAFNIVEFGINDIRQGIVHVVGPEQGLTLPGMTVVCGDSHTATHGAFGCLAHGIGTSEVEHVLATQCLVQKKSKNMLVRVDGVLGKGVTPKDVVLAIIGKIGTAGGTGYAIEFGGQVFRDMSIEGRMTVCNMAIEAGARVGMVAVDEKTIEYVKGRSYAPKGEQWDQAVAYWNTLHSDDDAVFDAVVELNGTEIEPQVSWGTSPEMVIPVSKAVPTLEQAKDDVQRNDWTRAYQYMGLNAGQALADIQLDRVFIGSCTNSRIEDIRAAAEVVKGRKVAPSIKQAMIVPGSGLVKQQAEKEGLDKIFLEAGFEWREPGCSMCLAMNADKLQPGEHCASTSNRNFEGRQGNGGRTHLVSPAMAAAAAIAGHFVDVRSF
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: PG023_COWPX
Sequence: MFDYLENEEVALDELKQMLRDRDPNDTRNQFKNNALHAYLFNEHCNNVEVVKLLLDSGTNPLHKNWRQLTPLGEYTNSRHGKVNKDIAMVLLEATGYSNINDFNIFTYMKSKNVDIDLIKVLVEHGFDFSVKCEKHHSVIENYVMTDDPVPEIIDLFIENGCSVIYEDEDDEYGYAYEEYHSQNDDYQPRNCGTVLHLYIISHLYSESDSRSCVNPEVVKCLINHGINPSSIDKNYCTALQYYIKSSHIDIDIVKLLMKGIDNTAYSYIDDLTCCTRGIMADYLNSDYRYNKDVDLDLVKLFLENGKPHGIMCSIVPLWRNDKETISLILKTMNSDVLQHILIEYITFSDIDISLVEYMLEYGAVVNKEAIHGYFKNINIDSYTMKYLLKKEGGDAVNHLDDGEIPIGHLCKSNYGRYNFYTDTYRQGFRDMSYACPILSTINFCLPYLKDINMIDKRGETLLHKAVRYNKQSLVSLLLESGSDVNIRSNNGYTCIAIAINESRNIELLNMLLCHKPTLDCVIDSLREISNIVDNAYAIKQCIRYAMIIDDCISSKIPESISKHYNDYIDICNQELNEMKKIIVGGNTMFSLIFTDHGAKIIHRYANNPELRAYYESKQNKIYTWKYMILFPNAIVKHNKIHKNIESVDDNTYISNLPYTIKYKIFEQQ
What is the function of this protein?
Substrate-specific adapter of SKP1-containing E3 ubiquitin-protein ligases which mediate the ubiquitination and subsequent proteasomal degradation of host target proteins.  Prevents activation and subsequent nuclear localization of NF-kappa-B in infected cells, by targeting NF-kappa-B RELA subunit to the SCF E3 ligase complex (By similarity).
What are the official names of this protein?
Ankyrin repeat domain-containing protein OPG023, Host range protein 1.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG023 family.
Protein: TUP11_SCHPO
Sequence: MASVEDATKVQEMLDALKAEYNALAHHSFASKARGNDYESSMIQSQIQEIEAFRKTVDDMYEKQKSIRETYEKDINKLKRELEELGVEANTASYRNRGERSELAASNNQVTHIDQEHPSQTKSTSQPPSNHLPAFQQIPPIHQSAYPQNNVAEVLMPPIPPSVEASSGQNFNQGIASQNPAISTSNLPSTTPLYIPPVNYGANQVSQQPNPQLPGVSNYYNPSATSKPAVNVQPPRIPTKATPSAEPSMTASANAGSISQAGPDGEYQGREQIAPVSDTEAARKTTSQSWYVTYNPACKRVFNINLVHTLEHPSVVCCVKFSNNGKYLATGCNQAANVFDVQTGKKLFTLHEESPDPSRDLYVRTIAFSPDGKYLVTGTEDRQIKLWDLSTQKVRYVFSGHEQDIYSLDFSHNGRFIVSGSGDRTARLWDVETGQCILKLEIENGVTAIAISPNDQFIAVGSLDQIIRVWSVSGTLVERLEGHKESVYSIAFSPDSSILLSGSLDKTIKVWELQATRSVGLSAIKPEGICKATYTGHTDFVLSVAVSPDSRWGLSGSKDRSMQFWDLQTGQSYLTCQGHKNSVISVCFSPDGRQFASGSGDLRARIWSIDPASP
What is the function of this protein?
Transcriptional repressor.
What are the official names of this protein?
Transcriptional repressor tup11.
What is the protein family that this protein belongs to?
Belongs to the WD repeat TUP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRPB2_COREF
Sequence: MTTPATPTRQTLLDAYFGEYGGQFVPEVLLPALDELERAYVEALEDPTFQQELDDLYTNYLGRPTPITECANLPLEGQGRGTARIFLKREDLVHGGAHKGNQTIGQALLAKRLGKTRLIAETGAGQHGTATAMVAALFGMKCTVYMGAKDVARQQPNVYRMRLMGAEVVAVDEQSGNGLSSAIDVAINDWVNNLEDTHYLLGTAAGPHPFPTLVKKFHSVISRESREQMLERTGALPDAVVACVGGGSNAIGAFAQYLEDQPGNEKVRLIGVEPAGYGLDTDLNGAPIHEGRTMHLHGSNSYALLDEDGNLRNSHSVSAGLDYPGVGPEHAHLKDTGRAEYVGATDAEALQAFRMLSRYEGIIPALESSHALAHALKMAAEATEPINILVNLSGRGDKDVAYVRQLLGDHAALDPATDVLTEVDVLGVLEELTPQADTA
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain 2.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: ILVD_CHLTE
Sequence: MRSDTIKKGFEKAPHRSLLKATGCVSTRDDFSKPFIGICNSFNELIPGHAHLQELGRIAKEAVREAGGVPFEFNTIGVCDGIAMGHVGMRYSLASRELIADSVETVVEAHRLDGLVCIPNCDKITPGMMMGALRTNVPVVFVSGGPMKAGHTPSGKTVDLISVFEAVGKCSTGEITEDELQTVEECGCPGCGSCSGMFTANSMNCLCEALGFALPGNGTILAADPRRNELVKAAAGRIIDLVKKEVRPRQILTRTSMLNAFALDLAMGGSTNTILHTLAIASEAELDFDFSELNDLSAKTPYICKVSPATTEVHIEDVDRAGGISAILKELSKVEGLLDLSAPTVTGKTLGENIASAEVLDRTVIRSVEEPYSTTGGLAVLYGNLAPNGAVVKTGAVSPAMMKHTGPAKVYDCQDDAIAGIMNGDVKSGDVVVIRYEGPRGGPGMPEMLSPTSAIIGRGLGDSVALITDGRFSGGSRGACVGHVSPEAADRGPIAAVQTGDMITIDIPARSMTVALDDETIRQRIEALPKFEPKIKKGYLARYARMVTSANTGAVLKNDF
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: PGAB_ECOLI
Sequence: MLRNGNKYLLMLVSIIMLTACISQSRTSFIPPQDRESLLAEQPWPHNGFVAISWHNVEDEAADQRFMSVRTSALREQFAWLRENGYQPVSIAQIREAHRGGKPLPEKAVVLTFDDGYQSFYTRVFPILQAFQWPAVWAPVGSWVDTPADKQVKFGDELVDREYFATWQQVREVARSRLVELASHTWNSHYGIQANATGSLLPVYVNRAYFTDHARYETAAEYRERIRLDAVKMTEYLRTKVEVNPHVFVWPYGEANGIAIEELKKLGYDMFFTLESGLANASQLDSIPRVLIANNPSLKEFAQQIITVQEKSPQRIMHIDLDYVYDENLQQMDRNIDVLIQRVKDMQISTVYLQAFADPDGDGLVKEVWFPNRLLPMKADIFSRVAWQLRTRSGVNIYAWMPVLSWDLDPTLTRVKYLPTGEKKAQIHPEQYHRLSPFDDRVRAQVGMLYEDLAGHAAFDGILFHDDALLSDYEDASAPAITAYQQAGFSGSLSEIRQNPEQFKQWARFKSRALTDFTLELSARVKAIRGPHIKTARNIFALPVIQPESEAWFAQNYADFLKSYDWTAIMAMPYLEGVAEKSADQWLIQLTNQIKNIPQAKDKSILELQAQNWQKNGQHQAISSQQLAHWMSLLQLNGVKNYGYYPDNFLHNQPEIDLIRPEFSTAWYPKND
What is the function of this protein?
Catalyzes the N-deacetylation of poly-beta-1,6-N-acetyl-D-glucosamine (PGA), a biofilm adhesin polysaccharide.  N-deacetylation promotes PGA export through the PgaA porin.
What are the official names of this protein?
Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase, PGA N-deacetylase, Poly-beta-1,6-GlcNAc N-deacetylase.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side.
Protein: CCR6_MOUSE
Sequence: MNSTESYFGTDDYDNTEYYSIPPDHGPCSLEEVRNFTKVFVPIAYSLICVFGLLGNIMVVMTFAFYKKARSMTDVYLLNMAITDILFVLTLPFWAVTHATNTWVFSDALCKLMKGTYAVNFNCGMLLLACISMDRYIAIVQATKSFRVRSRTLTHSKVICVAVWFISIIISSPTFIFNKKYELQDRDVCEPRYRSVSEPITWKLLGMGLELFFGFFTPLLFMVFCYLFIIKTLVQAQNSKRHRAIRVVIAVVLVFLACQIPHNMVLLVTAVNTGKVGRSCSTEKVLAYTRNVAEVLAFLHCCLNPVLYAFIGQKFRNYFMKIMKDVWCMRRKNKMPGFLCARVYSESYISRQTSETVENDNASSFTM
What is the function of this protein?
Receptor for the C-C type chemokine CCL20.  Binds to CCL20 and subsequently transduces a signal by increasing the intracellular calcium ion levels (PubMed:20068036).  Although CCL20 is its major ligand it can also act as a receptor for non-chemokine ligands such as beta-defensins (PubMed:25122636).  Binds to defensin DEFB1 leading to increase in intracellular calcium ions and cAMP levels.  Its binding to DEFB1 is essential for the function of DEFB1 in regulating sperm motility and bactericidal activity (By similarity).  Binds to defensins DEFB4 and DEFB4A/B and mediates their chemotactic effects (PubMed:20068036).  The ligand-receptor pair CCL20-CCR6 is responsible for the chemotaxis of dendritic cells (DC), effector/memory T-cells and B-cells and plays an important role at skin and mucosal surfaces under homeostatic and inflammatory conditions, as well as in pathology, including cancer and various autoimmune diseases.  CCR6-mediated signals are essential for immune responses to microbes in the intestinal mucosa and in the modulation of inflammatory responses initiated by tissue insult and trauma (PubMed:21376174).  CCR6 is essential for the recruitment of both the pro-inflammatory IL17 producing helper T-cells (Th17) and the regulatory T-cells (Treg) to sites of inflammation (PubMed:19050256).  Required for the normal migration of Th17 cells in Peyers patches and other related tissue sites of the intestine and plays a role in regulating effector T-cell balance and distribution in inflamed intestine (PubMed:19129757).  Plays an important role in the coordination of early thymocyte precursor migration events important for normal subsequent thymocyte precursor development, but is not required for the formation of normal thymic natural regulatory T-cells (nTregs).  Required for optimal differentiation of DN2 and DN3 thymocyte precursors (PubMed:24638065).  Essential for B-cell localization in the subepithelial dome of Peyers-patches and for efficient B-cell isotype switching to IgA in the Peyers-patches (PubMed:27174992).  Essential for appropriate anatomical distribution of memory B-cells in the spleen and for the secondary recall response of memory B-cells (PubMed:25505290).  Positively regulates sperm motility and chemotaxis via its binding to CCL20 (PubMed:23765988).
What are the official names of this protein?
C-C chemokine receptor type 6, C-C CKR-6, CC-CKR-6, CCR-6, KY411.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell surface.
Protein: SURE_DESAL
Sequence: MHILVTNDDGIHHPGLAALRDGLARDHRVQVVAPDRERSAIAHAITLLTPLRAFSQTNGNGIPSWAVNGTPADCVKLGVLELLGEKPDLVVSGINPGPNVGVNLNYSGTVSAAREAALLGIPAIAVSVSNPYGTHFSDAARFMQDLVADVAERGLPKGVFLNVNLPDVPMEEIAGVRICRQGIARLEEAFHVRKDPRNQPYYWQGSETQLFGESPDEDGVALRENCIAVTPVQCDMTDYGFLNQLKEWKVEKP
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEC31_PICGU
Sequence: MKIEEISKTSTFAWNNDPLPLLASGTVAGAVDADFSTSSSLEIWDIFSATNSKDPIFSASVDNRFYAIAWSKPSEGRSKGVLAGAFENGTIELWDVQELITSKDLQKASIFKSSAHSGPVKTLQFNPLQEHVLLSGGSNGQIFVWDTKKLSDPVAPGKAMTPMDEISCVSWNNSVSHIFATTGNSGYTSIWDLKSKREVLHLSYSANFSCVAWHPTQSTKLVTATGNDSDALILTWDLKNANAPEKIMRGHKKGILSLDWCKQDPEILISSGKDNATMLWNPIKGEKLGEYPTTANWAFHTRFAPAAPEIFATASFDGKIVIQSLQDTSPPMTSKVTTKNDNDFWNEISTTETQQPVFTVHQAPAWLKRTSSVSFGFGSKLVSISLDSDSHSVVKIQPFVKNGAVSETTSKFSQALKSNDFKDIIEARISDARHSKTDKADWEILSKLSGVGKEGFLKEIVSTEHEQANGKKPDVSSEDGTEPSRKEEGDNDFFEQLGESPIKSIPNFVPEGKFSIDTSDQSEADKTIIKLLLSNKIEDAISACLDQKKLSAALVLALDASPESKAKVRNAYFTNTKGDEIARLIYNASSKNITDIVANADVKSWKEIAAAIAAFSTDESDLSSKITELGDRIVQASENPSTEDRNNAMICYLAGNALEKIASIWLRELPEYEKSLLESPDDDVSTPSDAHFKSLNNFMEKLLAYRSITKANDTLGGPSIEPICNAILEYANLVAGYGQFELADSFLQLLPSDFAGLKTEKDRISRASGTKVQASNTRSTTSKATASRSYGKSPVPGASVPPTLPGNQTFAPAASTPYGGLAGQPAASSVLTPATPSFPSMPQPPQAPVSNRPPIASTPSIYGKPAPVGNPYAPQGATAFNPYKPPAPVAPEPVSAPPPAVSGPPKPAYRQETEGWNDLPDAFKQKTSTRRAAPAAVVSPSLSPALPANNFAPPKRNSAVAGPPPKGSRSSSRTAVPTIPTAASPSASTAQLHSRYAPPQSFNAPTEVSNGSGSPTPSVHAPPKNPYAPAATSSTNLPRNQYAPSVPTPSVQQPQTPKIGHASATPSGPSPNGPPKNPYAPTAQQVSMSPSGMVPPRTGSYGAAPSGVTAPPPPKVGGVLPPPGPVLTQPRSRNASAAAPVELTPPPTKPKYPAGDRSHIPEKSIQIYTSLDSLTQAVKPNVPERFIKHAEDMEKRLNFLYDHLNNDDLLSDDAIAELKKVCSAVEAKDYATATQLNVDFATNHSEQTGKWYPGLKRLISMAEATL
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein SEC31.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC31 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PRR30_MOUSE
Sequence: MLPVNKDQVLLQNTVPPGCPPQVLSQFVNSPAPNLASLCPHPTLPSSHFPLPAPPQAYFFSSLTQTHSPGPHFSSDSNSDFVPPHSSSHPRSSSCFGQNYTYFGEKLPSPHSISPSNYQLCVSPPLTGSSSLSQLQHSSPHSCQSPSRLQDLQSPKITSPVPSSPSPRIQNNKQTWQWPQSGSIKSSRGAGVCVPSKVDPAEFKDSGTLTQALVDHVGRRRIARDLQIQFLQRLWLGTPGHAPVVEYPICLVCLQIRTPSCPTPKYKTVPQLLAFPQLLPCVQGQESGPLRIGIGFGLRLPRGQARALHLLPPKNSTPVGVESQEEALQRQKSTIQESVQITGTLFQARSLRSIDLQSPKPSQCSRSLLQEPRQVAASPKAGPSVSKRSVTLGSILRKSPS
What are the official names of this protein?
Proline-rich protein 30.
Protein: AP2S1_MAIZE
Sequence: MIRFILLQNRQGKTRLAKYYVPLEDSEKHKVEYEVHRLVVNRDPKFTNFVEFRTHKVIYRRYAGLFFSICVDITDNELAYLECIHLFVEILDHFFSNVCELDLVFNFHKVYRYLILDEFILAGELQETSKRQ
What is the function of this protein?
Component of the adaptor complexes which link clathrin to receptors in coated vesicles.  Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.  AP2S1/AP17 is a subunit of the plasma membrane adaptor.  The complex binds polyphosphoinositides.
What are the official names of this protein?
AP-2 complex subunit sigma, Clathrin assembly protein 2 sigma small chain, Clathrin coat assembly protein AP17, Clathrin coat-associated protein AP17, Plasma membrane adaptor AP-2 17 kDa protein, Sigma2-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Cell membrane. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles in the plasma membrane.
Protein: TRPA_GRABC
Sequence: MSRIQTRFAALKREGRGALIPFIEAGDPDAETSQTLLHGLPAAGADLIEIGVPFTDPMADGPTIQRAGRRALEAGATLAKTLAMVETFRQQDKDTPIILMGYLNPIETYGHERFCVDAAAVGVDGLIIVDLPTEEADLILPFATANGLDVIRLVAPTTDDARLPHVLNGSSGFVYYVSITGITGTVTASAEQLAQNMPRLRRVTDLPVAIGFGIRNPAQAAEAVRQGDAAIVASALIDTLAETLDDGRATDRTVPAVLDQVRQLAEAVRSARLSARGA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RLUE_VIBPA
Sequence: MSSRTGHEKGRRTSQSKTGHFKRSGKPNRVEDQTTRRHPTRTAKAKAKAKANKPRVDLQNRKVIIFNKPYDTLSQFTDGDGRKTLADYIPVKDVYAAGRLDRDSEGLMVLTNDGILQAKLTQPKSKSPKTYWVQVDGAPQEQDLEKLRKGVELKDGMTLPAKVEVIDAPTIWERNPPVRFRANIPTTWLAITIIEGRNRQVRRMTAHIGFPTLRLVRYSMGDITLGDLQPGQWKEIQL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-2457 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase E, rRNA pseudouridylate synthase E, rRNA-uridine isomerase E.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RsuA family.
Protein: R35A1_ARATH
Sequence: MVKGRQGERVRLYVRGTILGYKRSKSNQYPNTSLVQVEGVNTTEEVSWYKGKRMAYIYKAKTKKNGSHYRCIWGKVTRPHGNSGVVRAKFTSNLPPKSMGSRVRVFMYPSNI
What are the official names of this protein?
60S ribosomal protein L35a-1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL33 family.
Protein: KAD_CLOK1
Sequence: MKIILLGPPGAGKGTQAKFISEEYSIPHISTGDIFRKNISDKTPLGIEAKEYLDKGQLVPDEVTINIVKDRLSEDDCESGFLLDGFPRTVYQAEALDSFLNANDNKIDMVLLIDVPRELIFDRMTGRRICPSCGASYHVKFNPPKLKDKCDICNNDIIQRKDDTESTVKDRLDVYEKQTEPLINYYKKQGVISTIEGSGEINQVFQRAKSALGAVCK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.