PharMolix/UniProtQA huggingface dataset:
Protein: SH_HRSV8
Sequence: MGNTSITIEFTSKFWPYFTLIHMILTPISLLIIITIMIAILNKLSEHKTFCNKTLELGQMYQINT
What is the function of this protein?
Viroporin that forms a homopentameric ion channel displaying low ion selectivity.  May play a role in virus morphogenesis and pathogenicity at various stages of the viral life cycle.  Accumulates at the membrane of the Golgi apparatus in infected cells and may facilitate virus release by modifying the secretory pathway.  May enhance host membrane permeability and disrupt cellular ion homeostasis, which can be sensed as damage-associated molecular patterns/danger signals, triggering NLRP3 inflammasome activation and inflammatory immune response.  Also inhibits host TNFA-mediated signaling pathway and may delay apoptosis, allowing time for the virus to replicate.
What are the official names of this protein?
Small hydrophobic protein, Small protein 1A.
What is the protein family that this protein belongs to?
Belongs to the orthopneumovirus small hydrophobic protein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein. Host Golgi apparatus membrane; Single-pass type II membrane protein. Host endoplasmic reticulum membrane; Single-pass type II membrane protein. Note=Present in very small amount in the virion. Detected in lipid rafts of host Golgi apparatus membrane.
Protein: RISB_XANOM
Sequence: MTHYEGDLRPPTARFAIIASRWNARITDVLVAGARQSLAGNGIGEDAIDVIRVPGAWEIPVAANRVAQSGQHGAIIALGCVIRGDTRHYEHVADLCAEGLMSVQLQTGVPVLNGVLAVERVEDAEARAGGSHGNKGEECALAALELVNLMELLP
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: AROD_COXBN
Sequence: MLNTPRICVVVIGKTLEEFLSQLEAAQTAVDFVELRIDYLEQINPNWVRIIKNHTHKKAILCCRARADGGKFLGTPEAQQEILQAGNDLGFDYLDIDLPVANKISIHEKKAKIIISYHNFLHTPPITELNFLLENMRLFNPDVFKFATKSEQYEDVKTLFKLLINKKNNENMIVLGMGEQGKIIRLLSPLLGGYLTFSSINGAISAPGQIDFKTMQDFYQRFYKISSPLKGED
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: CCL26_HUMAN
Sequence: MMGLSLASAVLLASLLSLHLGTATRGSDISKTCCFQYSHKPLPWTWVRSYEFTSNSCSQRAVIFTTKRGKKVCTHPRKKWVQKYISLLKTPKQL
What is the function of this protein?
Chemoattractant for eosinophils and basophils (PubMed:10415065, PubMed:10488147).  Acts as a ligand for C-C chemokine receptor CCR3 which triggers Ca(2+) mobilization in eosinophils (PubMed:10415065, PubMed:10488147, PubMed:11425309).  Also acts as a ligand for CX3C chemokine receptor CX3CR1, inducing cell chemotaxis (PubMed:20974991).
What are the official names of this protein?
C-C motif chemokine 26, CC chemokine IMAC, Eotaxin-3, Macrophage inflammatory protein 4-alpha, MIP-4-alpha, Small-inducible cytokine A26, Thymic stroma chemokine-1, TSC-1.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: DUT_ECO55
Sequence: MKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLDDAVELAPGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVWNRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RF1_DESOH
Sequence: MFDRLQDVERRFGELEGLMADPSIVNDREAYQKHSREHAELADIVDAYRRYKAVSDEIEKSRDLLEDRDPEIRELAKEEISRLKDERERLDGELQNLLTPKDPNDNKNVLVEIRAGTGGEEASLFAHDLFRMYWRYAETMGWKTEIMSSSVTGSGGFKEVIFMVYGKGAYSHLKFESGIHRVQRVPETEAQGRIHTSAVTVAVLAEAEEVELHIDPSEIKTDVFRSSGPGGQSVNTTDSAVRLTHLPTGVVVICQDEKSQLKNKNKAMKVLRARLLDRMIQDQNEKIAQNRKDQVGSGDRSGRIRTYNFPQGRVTDHRAGITLYKLESVLQGDLSELVNGLATYFQAERLKQADAS
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDO_CAEBR
Sequence: MVSFVQLVVQIREIFEHKMVDVDEVMKLMGSYKSDINEWRRFAIFDMNKYTRNLVDIGNGKYNLMILCWGPGMASSVHDHTDAHCFVKILDGELTETKYDWPKKKHTPLETIENKTYGLNGVSYMNDELGLHRMENQSHSNGAVSLHLYIPPYSTCNAFDERTGKKTKCTVTFYSKYGEKIDYHGSKEGK
What are the official names of this protein?
Cysteine dioxygenase, CDO.
What is the protein family that this protein belongs to?
Belongs to the cysteine dioxygenase family.
Protein: CTX13_LACTA
Sequence: MKYFVVALALVAAFACIAESKPAESEHELAEVEEENELADLEDAVWLEHLADLSDLEEARGFFGNTWKKIKGKADKIMLKKAVKIMVKKEGISKEEAQAKVDAMSKKQIRLYVLKYYGKKALQKASEKL
What is the function of this protein?
Insecticidal, cytolytic and antimicrobial peptide.  Forms voltage-dependent, ion-permeable channels in membranes.  At high concentration causes cell membrane lysis (By similarity).
What are the official names of this protein?
M-zodatoxin-Lt8c, M-ZDTX-Lt8c, Cytoinsectotoxin-1c, CIT-1c.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 06 (cytoinsectotoxin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRBB_ECOLI
Sequence: MSLTKSLLFTLLLSAAAVQASTRDEIERLWNPQGMATQPAQPAAGTSARTAKPAPRWFRLSNGRQVNLADWKVVLFMQGHCPYCHQFDPVLKQLAQQYGFSVFSYTLDGQGDTAFPEALPVPPDVMQTFFPNIPVATPTTFLVNVNTLEALPLLQGATDAAGFMARVDTVLQMYGGKKGAK
What are the official names of this protein?
Protein TrbB.
What are the subcellular locations of this protein?
Periplasm.
Protein: LIPB_MYCBP
Sequence: MTGSIRSKLSAIDVRQLGTVDYRTAWQLQRELADARVAGGADTLLLLEHPAVYTAGRRTETHERPIDGTPVVGTDRGGKITWHGPGQLVGYPIIGLAEPLDVVNYVRRLEESLIQVCADLGLHAGRVDGRSGVWLPGRPARKVAAIGVRVSRATTLHGFALNCDCDLAAFTAIVPCGISDAAVTSLSAELGRTVTVDEVRATVAAAVCAALDGVLPVGDRVPSHAVPSPL
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CVFB_STAHJ
Sequence: MALDKDIVGSIEFLEVIGLEGSTYLLKGPNGEQVKLNQSEINDEDELETGEEYSFFIYPNRSGELFATQNMPDITKDKYDFAKVLKTDRDGARVDVGLPREVLIPWEDLPKVKSLWPQTGDYVLVTLRIDRENQMFARLASETIVEKMFTPVYDDEKQNELIKARPYRLLRIGSFLLSKEGYKIFVHESERKEEPRLGEEVEVRIIGHNDRGELNGSFLPLAHERLDDDGQVIFDLLVEYEGELPFWDKSSPEAIKEVFNMSKGSFKRAIGHLYKHKIINIETGKISLTKKGWSRVEDK
What are the official names of this protein?
Conserved virulence factor B.
What is the protein family that this protein belongs to?
Belongs to the CvfB family.
Protein: EF2_PYRIL
Sequence: MSSAVRIVEKQLDEILAIARNPAQIRNAGTLAHVDHGKTTTTDSLLMGAGLLSPKVAGKALAMDYVPIEQLRQMTVKAANISLYFEYGGKPYLINFVDTPGHVDFTGHVTRSLRVMDGGLVVVDAVEGVMTQTETVVRQALEEYVRPVLFINKIDRLIKELRLSPQEIQQRILTIVKDFNALIEMFAPPEFKDKWKIDPGKGQMAMGSALHKWGITIPMAQKAGIKFSNIIDAYEKGYVDQLAQEFPLYKTLLSMIIEHVPPPNVAQKYRIPRLWRGDLNSEVGKALLEADPNGPTVIAVSKVNKDPHAGLIVTGRVFSGTIREGDEIYIIGRKMKKKVLQTYIYMGPSRIIVPYMPAGNIVALMGVDEARAGDTLVDPRISDIPPFEKMRYIAEPVVTVAIEPKNPAELAKLVEALKDLVIEDPTLDLKIDQETGQILLSGVGTLHLEIATWLLKERSKTEFTVSPPLIRFRETVRERSQVWEGKSPNKHNRLYFYVEPLDETTIELIATKEITEDQDPRERAKILREKAGWDTDEARGIWAIDDRYFNVIVDKTSGIQYLREIRDYIVQGFRWATEAGPLAQEPIRGVKVVLVDAVVHEDPAHRGPAQIMPATKNAIFAAMLSAKPTVLEPLLRLDIKVAPDYIGAVTSVLNKHRGKILDMTQQEYMAYLRAELPVLESFTISDELRAAAAGKIFWSMQFSRWAPVPESMLLDLVKQLRKKKGLKEEIPKPTDFVEVY
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLM4_MOUSE
Sequence: MIPRVIRLWLPSALFLSQVPGCVPLHGPSTITGAVGESLSVSCQYEEKFKTKDKFWCRGSLKVLCKDIVKTSSSEEVRNGRVTIRDHPDNLTFTVTYESLTLEDADTYMCAVDISLFDGSLGFDKYFKIELSVVPSEDPVTGSSLESGRDILESPTSSVGHTHPSVTTDDTIPAPCPQPRSLRSSLYFWVLVSLKLFLFLSMLGAVLWVNRPQRCSGGSSSRPCYENQ
What is the function of this protein?
Acts as an activating receptor in mast cells and macrophages.
What are the official names of this protein?
CMRF-35-like molecule 4, CLM-4, CD300C molecule 2, Dendritic cell-derived Ig-like receptor 1, DIgR1, Immunoglobulin superfamily member 7, IgSF7, Leukocyte mono-Ig-like receptor 2, Myeloid-associated immunoglobulin-like receptor 2, MAIR-2, MAIR-II.
What is the protein family that this protein belongs to?
Belongs to the CD300 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RS19_SYNP2
Sequence: MGRSLKKGPFIADSLLKKIEKLNASGDKQVIKTWSRASTILPQMVGHTIAVHNGRQHVPVFVSEQMVGHKLGEFAPTRTFKGHAKSDKKARR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RPIA_STAEQ
Sequence: MKDAKELKLMTLEDVLSQIENGMTIGIGTGSTIELLIPQIAELIQQKNYTITGVCTSNKTAFLAKELAMNIVDVNDVEKIDLAIDGADEVDSALNLIKGGGGALFREKVIDEMADRFVVVVDESKLVNYLGETFALPVEVDKFNWYQVAKKIERTYDIHVSRRVNEDVPFITDNGNYILDCSLQNRIPAYELHEFLIHLTGVLETGYFLDIADQVIVGTQEGVKILNKET
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: Y983_STRA5
Sequence: MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEESGVSRQAVYDNIKRTEKILEAYEMKLHMYSDYIVRSQIFDDILEKYTDDAFLQEKISILSSIDNRD
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein SAG0983.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: SYL_SHEPA
Sequence: MQEQYTPSEIEAKVQQHWQDTKTFEVTEDENKEKFYCLSMFPYPSGRLHMGHVRNYTIGDVVSRYQRLQGKNVLQPIGWDSFGLPAENAAIKNNTAPAPWTYENIDYMKNQLKMLGFGYDWSREIATCTPEYYRWEQWFFTKLYEKGLVYKKTSSVNWCPNDETVLANEQVIDGCCWRCDTTVEQKEIPQWFIKITEYAEELLNDIDTLEEWPEQVKTMQRNWIGRSEGIEMTFQVAGSDQSFDIYTTRPDTVMGVTYVAIAAGHPLAEQAAINNPALVEFIEECKNADTTEAAMAAMEKKGVATGLNAIHPITGKEVPIWVGNFVLMNYGTGAVMSVPAHDQRDYEFAKKYGLNIEAVIKPVDGEVDISEEAYTEKGVLFNSAEFDGLDFQAAFDAIDAKLTAEGKGKRQVNFRLRDWGVSRQRYWGAPIPMVTLADGTVMPTPEDQLPVILPEDVVMDGIQSPIKSDKEWAKTTINGQEAFRETDTFDTFMESSWYYARYCSPHADEMLDPAKANYWLPVDQYIGGIEHACMHLLYFRFFHKLLRDTGLVNSNEPAKRLLTQGMVLADAYYYNNEKGARVWVAPSDVTVQETDDKGRTVKAVDSEGHELVYTGMSKMSKSKNNGIDPQEMVDKYGADTVRLFMMFAAPPELTLEWQESSVEGAHRFIKRLWKTAHDHIANGTTAELDVKSLNAAQKELRRELHKTIAKVGDDIERRQMFNTAIASIMELMNRLQKAPSETDQDKALMQEALNAVIRLLYPIIPHTCFVLWNELGNQGAIEEVLWPEVDESALVEDSKLIIVQVNGKLRAKITVAADASKEEVEAAGMAEEGVVKHTEDKTVRKVIYVPGKLLNIVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_EHRCJ
Sequence: MKGTFQPSRIVRKRRHGFRSRMSTKMGRRILNRRRAQGRRVLCA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: MGP4_DICDI
Sequence: MASLIGSAKLPFNNEVELISDEIEKGLNDSTTIRKFFEKRAQIEEEYAKNLQKLCKATPILLKSGGTSDAFSMIVESTNQFSNHTISTIQRFNQDVNDPLAGFIKDLRGELKQYSLEGQNLAKERKQAFDSLKSSKALYEQMCNNPESDVMKVQQSEEEYKLQVQACNQYHSLYHQEKLPKIQNEIIRLETVRMQKMKTNLKKYITEFESIPQKQQQSIKDSEELINSIDTKQDIQSFTNFNKTLNTPTPDFQFESCESINGGGGGAAGRKSKKGGWRQTISVLKIGNAFMKDDGTIVNGNSSLNSSSSNINILNNPIVFKIPIEEIMFKQKSKFPNLDIPYILVLLVNLIKKLDNGMGMKTEGIFRIPGHTSEVNALKKLINEQGEYQFPPDLYSIHPIASLLKLWLREMPQPLIPNYVYDKSLECQSIEEFIVFFKFLPASNQKIITYLAGFLNELVQPDNVVTSKMNLDNVAMVFAPSFLRCDSQDMILANVDREKTLVKLIIEGYLKLSDVCPIQLDDIDSKIQIPSFSNNNNNSTTTTTTTTTTTVPSSTSTNITTNGASALGAESSTTPLPSLTTFSQSQSSSPPNQPSPSITPQQVSNLPPSYQPPQPPPTMAPPPLFNIPQQQQQQQVTNNNNSGGYTPPPLQYTQSSSNLPPIQLGVTNSPSKPQLSDKQKEKEKEKEKEKEKEKEREKEKEKEKEKEKEKEKEKEKKGHKKSSSSTSPNSSSLSISNFLSSNKDKDKEKDKEKEKEKEKEKDKEILATNSTPEKPVSNRMSLIFSQQLQQQLQQQIQQHQQLQQQSNGSPTSPISPSSANNSPSMSPSMVKRTIRPNLPPLQSGTSATTSSSSLTSSSSPTLTSSKDNIQKQQLPELNQQQQQQSPQAELKSSGIKSLLQRVPPPPSQS
What is the function of this protein?
Rho GTPase-activating protein involved in the signal transduction pathway.
What are the official names of this protein?
GTPase activating protein homolog 4, GTPase activating factor for raC protein DD, Rho GTPase-activating protein gacDD.
What are the subcellular locations of this protein?
Cytoplasm. Contractile vacuole.
Protein: GSDME_HORSE
Sequence: MFAKATRSFLREVDAEGDLIAVSNLNDSDKSQLLSLVTKKKRFWCWQRPKYQFLSVTLGDVLTEAQCLSPVVVESDFVKYEGKFENHVSGTIETALGKVKLNFGDKGLRESQSSFGTLRKQEVDLQQLIRDSVERTINLKNPVLQQMLESKNEVLCILTQKIVTTQKCVISEHIQTEEKCGGMVGIKTKTVQVSVTKDENIIKDASVALEIPAPTTIAYSVIELYVKLDGQFEFCLLRGKHGGFEHQRRSDIVFPDAGALQDFPFWDVPDAGQGLPTPDGPLSVLKQGTRLLEKNFFPFVELPEQHRTALNTVLQAVLSDEELLAVLEQVCDDLVHSLSPPLAMLGELKPPHRQDLTAFLRLVGYRVQGGCPCLEDGVGSQKLFSTAYFLVSALAEMPDNAAALLGTCCKLQIIPALCHLLHAMSHDGVCDLEDPALAPLKDTERFGVAQRLFASADINLERVQSSVKAVTPLKDPSVLPLILYISLKGLCALGREH
What is the function of this protein?
Pore-forming protein produced by cleavage by CASP3 or granzyme B (GZMB), which converts non-inflammatory apoptosis to pyroptosis or promotes granzyme-mediated pyroptosis, respectively.  After cleavage, moves to the plasma membrane, homooligomerizes within the membrane and forms pores of 10-15 nanometers (nm) of inner diameter, allowing the release of mature interleukins (IL1B and IL16) and triggering pyroptosis.  Binds to inner leaflet lipids, bisphosphorylated phosphatidylinositols, such as phosphatidylinositol (4,5)-bisphosphate.  Cleavage by CASP3 switches CASP3-mediated apoptosis induced by TNF or danger signals, such as chemotherapy drugs, to pyroptosis.  Mediates secondary necrosis downstream of the mitochondrial apoptotic pathway and CASP3 activation as well as in response to viral agents.  Exhibits bactericidal activity.  Cleavage by GZMB promotes tumor suppressor activity by triggering robust anti-tumor immunity.  Suppresses tumors by mediating granzyme-mediated pyroptosis in target cells of natural killer (NK) cells: cleavage by granzyme B (GZMB), delivered to target cells from NK-cells, triggers pyroptosis of tumor cells and tumor suppression.  May play a role in the p53/TP53-regulated cellular response to DNA damage.
What are the official names of this protein?
Gasdermin-E, Non-syndromic hearing impairment protein 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the gasdermin family.
What are the subcellular locations of this protein?
[Gasdermin-E, N-terminal]: Cell membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Gasdermin-E]: Cytoplasm, cytosol.
Protein: UPPP2_PARXL
Sequence: MNLSFLIFLSVLQGVTELFPVSSLGHTLLVPALFGMHIDKHAPQLLPFLVALHLGTAFALLWYFRKRWCALVRGFFASFGGRRNDDAHMMWALIIGTIPAGLVGLLLEKRLERIFHDLRIVAIALIVNGVLLWFGDRLQRTRAHQAPEKLTFRQAFFVGLAQIGALIPGFSRSGLTMIAGNAAGLTAEKAAEFSFLLGTPIIFAAGVLELPKLFHAPGQLADALLGGVLTAIAAYLSVRFLMRYFEGRGRLASFGVYCVIAGIVFLGWFLLHPQPV
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase 2, Bacitracin resistance protein 2, Undecaprenyl pyrophosphate phosphatase 2.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYOC_PSEAE
Sequence: MSTAVLNKHLADAHEVGHDHDHAHDSGGNTVFGFWLYLMTDCVLFASVFATYAVLVHHTAGGPSGKDIFELPYVLVETAILLVSSCTYGLAMLSAHKGAKGQAIAWLGVTFLLGAAFIGMEINEFHHLIAEGFGPSRSAFLSSFFTLVGMHGLHVSAGLLWMLVLMAQIWTRGLTAQNNTRMMCLSLFWHFLDIVWICVFTVVYLMGAL
What is the function of this protein?
Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E. coli that predominates when cells are grown at high aeration.  Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity).
What are the official names of this protein?
Cytochrome bo(3) ubiquinol oxidase subunit 3, Cytochrome o ubiquinol oxidase subunit 3, Cytochrome o subunit 3, Oxidase bo(3) subunit 3, Ubiquinol oxidase polypeptide III, Ubiquinol oxidase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRR_STREM
Sequence: MKSKVIVDELTMKRAITRITYEIIERNKQLDNVVLVGIKTRGVYLARRIQERLEQLESLHLAVGELDTKPFRDDMRVEEDTTSMPVDITGKDIILVDDVLYTGRTIRAAIDNLVSLGRPGRVSLAVLVDRGHRELPIRADYVGKNIPTSKTEEIVVEVVEVDGQDRISIVDPE
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: TTL12_HUMAN
Sequence: MEAERGPERRPAERSSPGQTPEEGAQALAEFAALHGPALRASGVPERYWGRLLHKLEHEVFDAGEVFGIMQVEEVEEEEDEAAREVRKQQPNPGNELCYKVIVTRESGLQAAHPNSIFLIDHAWTCRVEHARQQLQQVPGLLHRMANLMGIEFHGELPSTEAVALVLEEMWKFNQTYQLAHGTAEEKMPVWYIMDEFGSRIQHADVPSFATAPFFYMPQQVAYTLLWPLRDLDTGEEVTRDFAYGETDPLIRKCMLLPWAPTDMLDLSSCTPEPPAEHYQAILEENKEKLPLDINPVVHPHGHIFKVYTDVQQVASSLTHPRFTLTQSEADADILFNFSHFKDYRKLSQERPGVLLNQFPCENLLTVKDCLASIARRAGGPEGPPWLPRTFNLRTELPQFVSYFQQRERWGEDNHWICKPWNLARSLDTHVTKSLHSIIRHRESTPKVVSKYIESPVLFLREDVGKVKFDIRYIVLLRSVRPLRLFVYDVFWLRFSNRAFALNDLDDYEKHFTVMNYDPDVVLKQVHCEEFIPEFEKQYPEFPWTDVQAEIFRAFTELFQVACAKPPPLGLCDYPSSRAMYAVDLMLKWDNGPDGRRVMQPQILEVNFNPDCERACRYHPTFFNDVFSTLFLDQPGGCHVTCLV
What is the function of this protein?
Negatively regulates post-translational modifications of tubulin, including detyrosination of the C-terminus and polyglutamylation of glutamate residues (PubMed:20162578, PubMed:23251473).  Also, indirectly promotes histone H4 trimethylation at 'Lys-20' (H4K20me3) (PubMed:23251473).  Probably by controlling tubulin and/or histone H4 post-translational modifications, plays a role in mitosis and in maintaining chromosome number stability (PubMed:20162578, PubMed:23251473).  During RNA virus-mediated infection, acts as a negative regulator of the RIG-I pathway by preventing MAVS binding to TBK1 and IKBKE (PubMed:28011935).
What are the official names of this protein?
Tubulin--tyrosine ligase-like protein 12, Inactive tubulin--tyrosine ligase-like protein 12.
What is the protein family that this protein belongs to?
Belongs to the tubulin--tyrosine ligase family.
What are the subcellular locations of this protein?
Cytoplasm. Midbody. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Nucleus. Note=Predominantly localizes in the cytoplasm (PubMed:28011935). Partially colocalizes with vimentin in prostate cancer cells (PubMed:20162578).
Protein: DNAA_STRU0
Sequence: MTENETIFWNRILELAQSQLKQTTYEFFVLDARLVKVENQVATIYLDPMKELFWEQNLKDVILTAGFEVFNAHISVNYQFEDDLASEIEESTSNHIFSRQTINSLPAITSDLNPKYSFDNFIQGDENRWAVAASLAVANTPGTTYNPLFIWGGPGLGKTHLLNAIGNAVLLDNPKARVKYITAENFINEFVIHIRLDTMDELKEKFRNLDLLLIDDIQSLAKKTLLGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEQRLVTRFKWGLTVNITPPDFETRVAILTNKIQEYNFTFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKEIDKITVDIAAEAIRARKQDTPKMTIIPIEEIQTQVGKFYGVTVKEIKATKRTQNIVLARQVAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMIIEDESLRIEIETIKNKIK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNTP_ALCBS
Sequence: MNPIALLLLAFAMSTDAFAAAIGKGAILKKPRLTEAFRIGIIFGSIEAITPLVGWLIGKSAASYVEAWDHWIAFSLLTVLGLHMIYEGTRPDGGSEEHKAQKMSLLRTCLTAFSTSIDAMAVGVSLAFINVNIWIASALIGLATTLMVTIGIMLGRAIGSVMGHRAEIFGGLTLIAVGAWILYGQL
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: XERA_METTH
Sequence: MVDTMNMKRESEERQGLLERYNFPELIEDYLIELEIRNYSPNTIKTYKSIVKNFYEFLMNEDDLYDDRRVLRSFKRYIQYLKRDKKVTQNYIYLVTVVVKKFFEFSGIDCLEEVKAPKRTKSLPKSLNEDEVKSLINAVEVADDGSVIRRFIKTRDRLILSLLYSSGLRVSELVSLRINDIDPDERTIRIRGKGDKDRIVLFDENTRDLLMDYLKRRIHESEYLFLNRFGDPLTPRYVQMMIKNYARKAGIKKKVTPHILRHSFATHLLKNGVDIRAIQQLLGHSNLSTTQIYTSVDMQTLKNVYDRARLL
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.
What are the official names of this protein?
Tyrosine recombinase XerA.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.