PharMolix/UniProtQA huggingface dataset:
Protein: APRF_PSEAE
Sequence: MTMRRLMTWLFGAFLLLLREDAFALGLLDGYHLALENDPQFQAAIQEHEAGRQYRALGRAALLPRLVYSYNRGRSWSDVTQTTTRGDFKEDRDYDSYVSTLSLQQPLFDYEAFSRYRKGVAQALLSDERFRSQSQELLVRVLEAYTGALLAQDQIELARAQKRSYREQFQLNQRQFERGNGTRTDTLETQARFNLAQAQEIEARDSQDAALRELERLVGAPLEIADLAPLGERFQVRPLSPASYTAWRDLALAENPELASLRHAVDVARYEVEQNRADFLPRLGLYASTGKSKSGSENTYNQRYETDSVGIQLSVPLFSGGETLAATRQATHRMEKSHYDLDDKVRETLNQVRKMYNQSSSSAAKIRAYEMTVDSARTLVMATRKSIAAGVRVNLDLLNAEQALYSAMNELSKAKYDYLTAWARLRFYAGVLDEADLELVAANFVSGETPARRRDCATTDCPAPLHTLSKTDTEENRSALN
What is the function of this protein?
Involved in the secretion of alkaline protease.
What are the official names of this protein?
Alkaline protease secretion protein AprF.
What is the protein family that this protein belongs to?
Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: CH10_SOLM1
Sequence: MKLKPLGDRVLVKRLEQEEVTKGGIIIPDSAKEKPMKGEVIAVGPGKLAEDGKHLKMHVEKGDLVLFNKYAGTEIKVDDEDFLVMREDDILAVIEA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EHMT1_MOUSE
Sequence: MAAADAEQAVLAKQETKQDCCMKTELLREDTPMAADEGSTEKQEGETPMAADGETNGSCEKSGDPSHLNAPKHTQENTRASPQEGTNRVSRVAENGVSERDTEVGKQNHVTADDFMQTSVIGSNGYFLNKPALQGQPLRTPNILTSSLPGHAAKTLPGGASKCRTLSALPQTPTTAPTVPGEGSADTEDRKPTASGTDVRVHRARKTMPKSILGLHAASKDHREVQDHKEPKEDINRNISECGRQQLLPTFPALHQSLPQNQCYMATTKSQTACLPFVLAAAVSRKKKRRMGTYSLVPKKKTKVLKQRTVIEMFKSITHSTVGAKGEKALDDSALHVNGESLEMDSEDEDSDELEDDEDHGAEQAAAFPTEDSRTSKESMSETDRAAKMDGDSEEEQESPDTGEDEDGGDESDLSSESSIKKKFLKRRGKTDSPWIKPARKRRRRSRKKPSSMLGSEACKSSPGSMEQAALGDSAGYMEVSLDSLDLRVRGILSSQTENEGLASGPDVLGTDGLQEVPLCSCRMETPKSREISTLANNQCMATESVDHELGRCTNSVVKYELMRPSNKAPLLVLCEDHRGRMVKHQCCPGCGYFCTAGNFMECQPESSISHRFHKDCASRVNNASYCPHCGEEASKAKEVTIAKADTTSTVTLAPGQEKSLAAEGRADTTTGSIAGAPEDERSQSTAPQAPECFDPAGPAGLVRPTSGLSQGPGKETLESALIALDSEKPKKLRFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQSKRSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLDAVKYLIKAGAQVDPKDAEGSTCLHLAAKKGHYDVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVELVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLSSQVWSALQMSKALRDSAPDKPVAVEKTVSRDIARGYERIPIPCVNAVDSELCPTNYKYVSQNCVTSPMNIDRNITHLQYCVCVDDCSSSTCMCGQLSMRCWYDKDGRLLPEFNMAEPPLIFECNHACSCWRNCRNRVVQNGLRARLQLYRTQDMGWGVRSLQDIPLGTFVCEYVGELISDSEADVREEDSYLFDLDNKDGEVYCIDARFYGNVSRFINHHCEPNLVPVRVFMSHQDLRFPRIAFFSTRLIQAGEQLGFDYGERFWDVKGKLFSCRCGSSKCRHSSAALAQRQASAAQEPQENGLPDTSSAAAADPL
What is the function of this protein?
Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin.  H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones.  Also weakly methylates 'Lys-27' of histone H3 (H3K27me).  Also required for DNA methylation, the histone methyltransferase activity is not required for DNA methylation, suggesting that these 2 activities function independently.  Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1.  During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in G0/G1 transition in cell cycle.  In addition to the histone methyltransferase activity, also methylates non-histone proteins: mediates dimethylation of 'Lys-373' of p53/TP53.  Represses the expression of mitochondrial function-related genes, perhaps by occupying their promoter regions, working in concert with probable chromatin reader Baz2b (PubMed:32103178).
What are the official names of this protein?
Histone-lysine N-methyltransferase EHMT1, Euchromatic histone-lysine N-methyltransferase 1, Eu-HMTase1, G9a-like protein 1, GLP, GLP1, Lysine N-methyltransferase 1D.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associates with euchromatic regions.
Protein: RL24_THEVO
Sequence: MYDKLNVALSKDLRKKYGIRSFPIVKGDVVKVVSGARKGEGGKVAEVDHHSGLVIVEGITIAKIDGKQKGFGISPEKLQITHLDLSRSERFQKIKELANIKHITIQEEPIQEEQQKTEETKQEIAPEEVEAKEAQDKQEVKENDQ
What is the function of this protein?
Located at the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: MED14_HUMAN
Sequence: MAPVQLENHQLVPPGGGGGGSGGPPSAPAPPPPGAAVAAAAAAAASPGYRLSTLIEFLLHRAYSELMVLTDLLPRKSDVERKIEIVQFASRTRQLFVRLLALVKWANNAGKVEKCAMISSFLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPPDPITKIEKQATLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDDPDVPWRLLKLEILVEDKETGDGRALVHSMQISFIHQLVQSRLFADEKPLQDMYNCLHSFCLSLQLEVLHSQTLMLIRERWGDLVQVERYHAGKCLSLSVWNQQVLGRKTGTASVHKVTIKIDENDVSKPLQIFHDPPLPASDSKLVERAMKIDHLSIEKLLIDSVHARAHQKLQELKAILRGFNANENSSIETALPALVVPILEPCGNSECLHIFVDLHSGMFQLMLYGLDQATLDDMEKSVNDDMKRIIPWIQQLKFWLGQQRCKQSIKHLPTISSETLQLSNYSTHPIGNLSKNKLFIKLTRLPQYYIVVEMLEVPNKPTQLSYKYYFMSVNAADREDSPAMALLLQQFKENIQDLVFRTKTGKQTRTNAKRKLSDDPCPVESKKTKRAGEMCAFNKVLAHFVAMCDTNMPFVGLRLELSNLEIPHQGVQVEGDGFSHAIRLLKIPPCKGITEETQKALDRSLLDCTFRLQGRNNRTWVAELVFANCPLNGTSTREQGPSRHVYLTYENLLSEPVGGRKVVEMFLNDWNSIARLYECVLEFARSLPDIPAHLNIFSEVRVYNYRKLILCYGTTKGSSISIQWNSIHQKFHISLGTVGPNSGCSNCHNTILHQLQEMFNKTPNVVQLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTAYQCFSILPQSSTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKLVEGFYPAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQTLQLKVTPENAGQWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVRDLMANLTLPPGGRP
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 14, Activator-recruited cofactor 150 kDa component, ARC150, Cofactor required for Sp1 transcriptional activation subunit 2, CRSP complex subunit 2, Mediator complex subunit 14, RGR1 homolog, hRGR1, Thyroid hormone receptor-associated protein complex 170 kDa component, Trap170, Transcriptional coactivator CRSP150, Vitamin D3 receptor-interacting protein complex 150 kDa component, DRIP150.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 14 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MTGA_NITEU
Sequence: MKLAQARRPATSKPRLISTWLLRPLLLLLTAALLYQSWFLLHIVYWRSYSPTTSAFMQDRLKIMRQQNPAASLQHQWVDYEQISSHLKRAVIAAEDARFLQHQGFDYKAIETAWKKNLKQRKWAAGGSTISQQLAKNLFLSTEKTVWRKSRETLITLMLEEFLTKRRILEIYLNIIEWGDGIFGIEAAARHYFGISAASLTPAQAAWLASIIPNPRFYDTRRTLPKLLNKSRIILSRLPAAKIP
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: JHBP_MANSE
Sequence: VLSDQGALFEPCSTQDIACLSRATQQFLEKACRGVPEYDIRPIDPLIISSLDVAAYDDIGLIFHFKNLNITGLKNQKISDFRMDTTRKSVLLKTQADLNVVADVVIELSKQSKSFAGVMNIQASIIGGAKYSYDLQDDSKGVKHFEVGQETISCESIGEPAVNLNPELADALLKDPDTTHYRKDYEAHRVSIRQRSLCKIVELCYVDVVHNIRAVAKILPSTAFFTDVN
What is the function of this protein?
Prevents juvenile hormone from being hydrolyzed by general esterases by combining with it specifically.
What are the official names of this protein?
Juvenile hormone-binding protein.
What are the subcellular locations of this protein?
Secreted.
Protein: RPF_MICLU
Sequence: MDTMTLFTTSATRSRRATASIVAGMTLAGAAAVGFSAPAQAATVDTWDRLAECESNGTWDINTGNGFYGGVQFTLSSWQAVGGEGYPHQASKAEQIKRAEILQDLQGWGAWPLCSQKLGLTQADADAGDVDATEAAPVAVERTATVQRQSAADEAAAEQAAAAEQAVVAEAETIVVKSGDSLWTLANEYEVEGGWTALYEANKGAVSDAAVIYVGQELVLPQA
What is the function of this protein?
Factor that stimulates resuscitation of dormant cells.  Has peptidoglycan (PG) hydrolytic activity.  Has little to no effect on actively-growing cells.  PG fragments could either directly activate the resuscitation pathway of dormant bacteria or serve as a substrate for endogenous Rpf, resulting in low molecular weight products with resuscitation activity.  In pM quantities promotes the resuscitation and growth of dormant, nongrowing cells from M. luteus in addition to Mycobacterium tuberculosis, M. avium, M. bovis, M. kansaii and M. smegmatis.  Hydrolyzes endogeneous cell walls, peptidoglycan preparations from Mycobacterium tuberculosis and M. smegmatis as well as an artificial lysozyme substrate 4-methylumbelliferyl-beta-D-N,N',N''-triacetylchitotrioside (MUF tri-NAG).  Overexpression in E. coli (when the enzyme is targeted to the periplasm) causes cell lysis.
What are the official names of this protein?
Resuscitation-promoting factor Rpf.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase family. Rpf subfamily.
What are the subcellular locations of this protein?
Secreted. Cell surface. Note=Found in culture supernatant, also accumulates on the cell surface.
Protein: MASY_EMENI
Sequence: MSQVDAQLKDVAILGSVSNEARKILTKEACAFLAILHRTFNPTRKALLQRRVDRQAEIDKGHLPDFLPETKHIRDDPSWKGAPPAPGLVDRRVEITGPTDRKMVVNALNSDVWTYMADFEDSSAPTWDNMINGQINLYDAIRRQVDFKQGQKEYKLRTDRTLPTLIARARGWHLDEKHFTVDGEPISGSLFDFGLYFFHNAKELVARGFGPYFYLPKMESHLEARLWNDVFNLAQDYIGMPRGTIRGTVLIETITAAFEMEEIIYELRDHSSGLNCGRWDYIFSFIKKFRQHPNFVLPDRSDVTMTVPFMDAYVKLLIKTCHKRGVHAMGGMAAQIPIKDNAEANDKAMEGVRADKLREVRAGHDGTWVAHPALASIASEVFNKYMPTPNQMHVRREDVNITANDLLNTNVPGKITEDGIRKNLNIGLSYMEGWLRGVGCIPINYLMEDAATAEVSRSQLWQWARHGVTTSEGKKVDKAYALRLLKEQADALAAKGPKGNKFQLAGRYFAGQVTGEDYADFLTSLLYNEISSPGTASKL
What are the official names of this protein?
Malate synthase, glyoxysomal.
What is the protein family that this protein belongs to?
Belongs to the malate synthase family.
What are the subcellular locations of this protein?
Glyoxysome.
Protein: ASSY_MYCBT
Sequence: MSERVILAYSGGLDTSVAISWIGKETGREVVAVAIDLGQGGEHMDVIRQRALDCGAVEAVVVDARDEFAEGYCLPTVLNNALYMDRYPLVSAISRPLIVKHLVAAAREHGGGIVAHGCTGKGNDQVRFEVGFASLAPDLEVLAPVRDYAWTREKAIAFAEENAIPINVTKRSPFSIDQNVWGRAVETGFLEHLWNAPTKDIYAYTEDPTINWGVPDEVIVGFERGVPVSVDGKPVSMLAAIEELNRRAGAQGVGRLDVVEDRLVGIKSREIYEAPGAMVLITAHTELEHVTLERELGRFKRQTDQRWAELVYDGLWYSPLKAALEAFVAKTQEHVSGEVRLVLHGGHIAVNGRRSAESLYDFNLATYDEGDSFDQSAARGFVYVHGLSSKLAARRDLR
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOBR1_ARATH
Sequence: MARTFILWLHGLGDSGPANEPIQTQFKSSELSNASWLFPSAPFNPVTCNNGAVMRSWFDVPELPFKVGSPIDESSVLEAVKNVHAIIDQEIAEGTNPENVFICGLSQGGALTLASVLLYPKTLGGGAVLSGWVPFTSSIISQFPEEAKKTPILWSHGTDDRMVLFEAGQAALPFLKEAGVTCEFKAYPGLGHSISNKELKYIESWIKRRLKGSSSTCLQLNCLKEMFH
What is the function of this protein?
Possesses carboxylesterase activity in vitro with a preference for short acyl chain substrates.  Functions as a negative regulator of the hypersensitive response (HR) triggered by the bacterial type III effector protein AvrBsT (PubMed:17293566).  Possesses phospholipase A2 (PLA2) activity and hydrolyzes phosphatidylcholine (PC), a lipid that is hydrolyzed by phospholipase D (PLD) to produce phosphatidic acid (PA).  Required to suppress AvrBsT-dependent HR and PLD-dependent production of PA in response to AvrBsT elicitation (PubMed:19918071).
What are the official names of this protein?
Carboxylesterase SOBER1, Phospholipase A2 SOBER1, Protein SUPPRESSOR OF AVRBST-ELICITED RESISTANCE 1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.
Protein: NU5M_BOVIN
Sequence: MNMFSSLSLVTLLLLTMPIMMMSFNTYKPSNYPLYVKTAISYAFITSMIPTMMFIHSGQELIISNWHWLTIQTLKLSLSFKMDYFSMMFIPVALFVTWSIMEFSMWYMYSDPNINKFFKYLLLFLITMLILVTANNLFQLFIGWEGVGIMSFLLIGWWYGRADANTAALQAILYNRIGDIGFILAMAWFLTNLNTWDLQQIFMLNPSDSNMPLIGLALAATGKSAQFGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLLIRFYPLTENNKYIQSITLCLGAITTLFTAMCALTQNDIKKIIAFSTSSQLGLMMVTIGINQPYLAFLHICTHAFFKAMLFMCSGSIIHSLNDEQDIRKMGGLFKAMPFTTTALIVGSLALTGMPFLTGFYSKDLIIEAANTSYTNAWALLMTLIATSFTAIYSTRIIFFALLGQPRFPTLVNINENNPLLINSIKRLLIGSLFAGYIISNNIPPTTIPQMTMPYYLKTTALIVTILGFILALEISNMTKNLKYHYPSNAFKFSTLLGYFPTIMHRLAPYMNLSMSQKSASSLLDLIWLEAILPKTISLAQMKASTLVTNQKGLIKLYFLSFLITILISMILFNFHE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PORD_ZOBGA
Sequence: MILKQAILTLVLVNANLFAQEPPKTYSSTDKETRQGPPKPPMGKRWVLNPDFSDEFNGTELDTTKWLDHHPTWIGRAPGLFMSSQVSVGDGFLKMEGKKLEKDTIVHAYGKDITFNIAGAAVVSKKATKFGYYECRVKAAATTMSTTFWFSSSNNFKGPKDCDRYGLEWDIHESIGREGDFNGSYFASGMHSNAHFWYTDCNGKKYDHRAPQVKFEDAKLTSEDFNVYGGWWRDESTASYYYNNRPPKHQKFYDKVKKKPFDQPMYMRLVNETYPFPWIELPNAEELSDPSKNTVYYDWVRAYRLVDVNDPNSEVEKDPTLKLYHENVTFPSATIEHKRSKSLEIPLSYQANEDREIAFILFDNEGKKIKEAILTAYAGYANLEYTLQLDQKLPLGSPYKLSAHIRPLKGNKKNSLDESTVYIHLTK
What is the function of this protein?
Cleaves the sulfated polysaccharide porphyran at the (1->4) linkages between beta-D-galactopyranose and alpha-L-galactopyranose-6-sulfate, forming mostly the disaccharide alpha-L-galactopyranose-6-sulfate-(1->3)-beta-D-galactose.
What are the official names of this protein?
Beta-porphyranase D.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PEPQ_SHIF8
Sequence: MESLASLYKNHIATLQERTRDALARFKLDALLIHSGELFNVFLDDHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPTSFWTEDVEVIALPKADGIGSLLPAARGNIGYIGLVQERALQLGIEASNINPKGVIDYLHYYRSFKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIVALNEHAAVLHYTKLDHQAPEEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKDVNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMPHGIGHPLGLQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIYFIESLLAPWREGQFSKHFNWQKIEALKPFGGIRIEDNVVIHENNVENMTRDLKLA
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: HOGA1_DANRE
Sequence: MFAHRSFSLLCRRSAVTSWRSQSHTAGKRLDISGIYPPIATPFTEPEDVDYQKLDDNIRKYGRLPFRGLVVQGSNGEYPYLTAEERVEVVKRVKQALPKDKLVMAGSGCESTRATIQMSQRMADAGADCVLVVTPCFYRGRMDSRALINHYSKVADSCSVPVVLYSVPANTGLDLPVDAVIQLSKHPNIVGLKDSGGDITRIALMVQKTRSQDFQVLAGSAGFLMAAYAVGAVGGVCALANVLGQQVCELAQLCVSGRWDEAKELQYRLIEPNTAVTRGFGVPALKLAMDWFGYHGGICRSPLQPLSKADLEALRGKFSSNGWL
What is the function of this protein?
Catalyzes the final step in the metabolic pathway of hydroxyproline.
What are the official names of this protein?
4-hydroxy-2-oxoglutarate aldolase, mitochondrial, Dihydrodipicolinate synthase-like, DHDPS-like protein, Probable 2-keto-4-hydroxyglutarate aldolase, Probable KHG-aldolase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DMA1_YEAST
Sequence: MSTNTVPSSPPNQTPPAASGIATSHDHTKFNNPIRLPISISLTINDTPNNNSNNNSVSNGLGILPSRTATSLVVANNGSANGNVGATAAAAATVETNTAPAVNTTKSIRHFIYPPNQVNQTEFSLDIHLPPNTSLPERIDQSTLKRRMDKHGLFSIRLTPFIDTSSTSVANQGLFFDPIIRTAGAGSQIIIGRYTERVREAISKIPDQYHPVVFKSKVISRTHGCFKVDDQGNWFLKDVKSSSGTFLNHQRLSSASTTSKDYLLHDGDIIQLGMDFRGGTEEIYRCVKMKIELNKSWKLKANAFNKEALSRIKNLQKLTTGLEQEDCSICLNKIKPCQAIFISPCAHSWHFHCVRRLVIMNYPQFMCPNCRTNCDLETTLESESESEFENEDEDEPDIEMDIDMEINNNLGVRLVD
What is the function of this protein?
E3 ubiquitin-protein ligase which functions in cell cycle retarding in conjunction with the UBC4 and UBC13/MMS2 complex, 2 E2 ubiquitin conjugating enzymes (PubMed:18202552).  Involved in nutritional control of the cell cycle (PubMed:15319434).  Targets the G1 cyclin PCL1 for destruction (PubMed:23264631).  Required for proper spindle positioning, likely regulating septin ring deposition at the bud neck (PubMed:15146058).
What are the official names of this protein?
E3 ubiquitin-protein ligase DMA1, Checkpoint forkhead associated with RING domains-containing protein 1, Defective in mitotic arrest protein 1, RING-type E3 ubiquitin transferase DMA1.
What is the protein family that this protein belongs to?
Belongs to the DMA1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACT1_OXYFA
Sequence: MSDQQTCVIDNGSGVVKAGFAGEDAPRAVFPSIVGRPKNVSALIGVDSASEYLGDEAQQKRGVLKIWNHTFYVELRVQPDEHPILLTEAPLSPKTNREKMTQIIFETFNLPALYVAIQAVLSLYSRGRTTGIVCDAGDGLTHTVPIYEGFSIPHAVSTIQLAGRDLTTFLAKLFTERGYNFTSSAELEIVRDIKEKLCFLALNYESALKQSHDSSQFEKNYELPHGKVITIGSERFRCPEYLFKPLEMNGRELDSIQDLTYKSIQECDVDVRRDLYQNIILSGGTTMYEGIGERLLKEIENRAPKSINVKVIASPDRRFAVWRGGSTLTSLSTFASMWITKEDYDENGASIVHRKCI
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin, macronuclear.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: MINC_PSEMY
Sequence: MSQADLLAQDPVFQLKGSMLAITVMELAHNDLDRLDAQLTEKVAQAPAFFSNTPLVLALDKLPEGEGELNLAELMAVCRRHGLRTLAIRASREGDIAAAEAMDLPVLPPSGARERLLDPAPKKVEEKPAEPEHKPSRIVTSPVRGGQQVYAQGGDLIVLAPVSAGAELLADGNIHVYAPMRGRALAGIKGNTKARIFCQQMGAEMLSIAGHYKVAEDLRRDPLWGDAVHVSLSGDVLNITRL
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: HXB7_RAT
Sequence: MSSLYYANALFSKYPAASSVFAPGAFPEQTSCAFASNPQRPGYGAGPGAPFSASVQGLYSGGGGMAGQSAAGVYEAGYGLEPSSFNMHCAPFEQNLSGVCPGDPAKAAGAKEQRDSDLAAESNFRIYPWMRSSGTERKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTSGPGTTGQDKAEADEEEEEEE
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-B7, Homeobox protein R1B.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL20_STAAR
Sequence: MPRVKGGTVTRARRKKTIKLAKGYFGSKHTLYKVAKQQVMKSGQYAFRDRRQRKRDFRKLWITRINAAARQHEMSYSRLMNGLKKAGIDINRKMLSEIAISDEKAFAQLVTKAKDALK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: SYS_GEOMG
Sequence: MLDPKHLRENFESVEQRLATRGGAVTLDRFRELDSRRRELLREAESLKAVRNAASEEISRIKDKSQAQPRIAEMREVSAKIKVLDDDLRGVDDDLQAVLLTIPNIPHQSVPVGASEADNREVRKWGEPPRFGFTPRPHWEIGEGLGILDFERGAKLTGARFTLYRGAGARLERALINFMLDLHTEKHGYEETLPPFMVNRESMTGTGQLPKFEEDLFHLDGTDYYLIPTAEVPVTNIHRGEILKGSDLPLSYTAYTPCFRKEAGSYGKDVRGLIRQHQFNKVELVKFTHPSTSYAELERLLANAEEVLRQLGLHYRVVELCTGDMGFSAAKTYDIEVWLPAQDTYREISSCSNFEDFQARRASIRFREDDKAKPEFAHTLNGSGLAVGRTLVAILENYQQEDGTVVIPEVLRPYMGGCSSIGR
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_HALHL
Sequence: MDDDRKKALGAALGQIEKQFGKGAVMRMGDARAVRGDVKSISTGSLALDVALGIGGLPRGRVVEIYGPESSGKTTLTLHIIAEAQKAGGAAAFVDAEHALDPDYAEAVGVDINDLLVSQPDTGEQALEIADMLVRSGGLDVVVVDSVAALTPKAEIEGEMGDSHVGLQARLMSQALRKLTGSIQRSNTLVVFINQIRMKIGVMFGSPETTTGGNALKFYSSVRMDIRRLGAIKKGDEVLGNETRVKVVKNKMAPPFKQAEFEILYGEGISREGEIIDMGVAQGFVDKSGAWYSYNGDRIGQGKDNARQFLRNNPQIAADIEARIREKVLGTALPEAEPTEDAASDTEQKSGKGS
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_BRUAB
Sequence: MFVSTAFAQTATESQPASTAGEHGAADAVHTETGVAHDAGHGSGVFPPFDSTHYASQVLWLAITFGLFYLFLSRVVLPRIGGVIETRRDRIAQDLEQAARLKQDADNAIAAYEQELAQARSKAASIAEAAREKGKGEADAERASAEAVLESKLKEAEERIAAIKAKAMSDVGNIAEETTATIVEQLLGLTADKASVSEAVKAIRASNA
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.