PharMolix/UniProtQA huggingface dataset:
Protein: RPPH_CAMJE
Sequence: MENEKNYRPNVAAIVLSSSYPFECKIFIARRSDMDNIWQFPQGGIDKGESVKNALFRELKEEIGTDEVEIIAEYPEWLSYDFPSKIVKKMYPYDGQIQKYFLVRLKHGATININTKHPEFDDYQFVSVKQIFEMINHFKKNIYVRVIKYFEEKGYI
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: TRPD_FRATF
Sequence: MISLKSIVDKLYNLEDLSYQESYQLFDYFIKGQIELPLQTSILIALKLKKETSIEIAAAVEALFDNTKEFPKIKGDLAGIVGTGGDGFNTINISTTAAIVAATAGYKVAKHGGRSVSSKSGSFDLLESFGVNIELAPDQTKQCLELYNMGFLFAPFYSDGFRHIKEARTILKTRTIFNILGPLINPARPNKVVIGVYSKDLILPMAKTLVNLGIDRAVVVYGSGLDEVAIHDDTYVAEIQNNQIIEYKVSPVDFGIYTYAIKDLEGGLPEQNREIIKQILLGKGKEAHNAAVAVNVAMLMRLYDKDDLKQNTQEVLEIIKSGKCFNTLQQVINYSNK
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: IF4E2_MOUSE
Sequence: MNNKFDALKDDDSGDHDQNEENSTQKDGEKEKTDRDKSQSSGKRKAVVPGPAEHPLQYNYTFWYSRRTPGRPTSSQSYEQNIKQIGTFASVEQFWKFYSHMVRPGDLTGHSDFHLFKEGIKPMWEDDANKNGGKWIIRLRKGLASRCWENLILAMLGEQFMVGEEICGAVVSVRFQEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDSIKMPGRLGPQRLLFQNLWKPRLNVP
What is the function of this protein?
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation (PubMed:15153109).  Acts as a repressor of translation initiation (By similarity).  In contrast to EIF4E, it is unable to bind eIF4G (EIF4G1, EIF4G2 or EIF4G3), suggesting that it acts by competing with EIF4E and block assembly of eIF4F at the cap (PubMed:15153109).  In P-bodies, component of a complex that promotes miRNA-mediated translational repression (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 4E type 2, eIF-4E type 2, eIF4E type 2, eIF4E-2, mRNA cap-binding protein type 2, Eukaryotic translation initiation factor 4E-like 3, eIF4E-like protein 4E-LP.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic initiation factor 4E family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, P-body.
Protein: LINX_SPHIB
Sequence: MANRLAGKVALITGGASGLGAAQAKRFAEEGAKVVIGDLNEEMAKGVVAEIRAAGGDALFIRLDVTDAASWNNAIAAAVEAFGGLTTLSNTAGIIHPGGFEEESIEGWNKMVAVNQTAIFLGIKAAIPELVKSGNGSIINISSLIGMFPTAGNASYCATKAAVRIMSKAAALEFVDRGVRVNTIVPGGMNTPITANVPPDVLKQQTSQIPMGKLGDPIDIANGALFLASDEAKYITGVDLPIDGGWSVGV
What is the function of this protein?
Catalyzes the degradation of 2,5-dichloro-2,5-cyclohexadiene-1,4-diol (2,5-DDOL) into 2,5-dichlorohydroquinone (2,5-DCHQ) in vitro.  LinX appears not to be involved in gamma-hexachlorocyclohexane (gamma-HCH) degradation pathway, in contrast to LinC which has the same enzymatic activity.
What are the official names of this protein?
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase LinX, 2,5-DDOL dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: B2MG_MICEM
Sequence: MACSVVVALLALLSLSGLEAIQHAPKIQVYSRHPAENGKPNFLNCYVSGFHPSDIEVDLLKNGKKIEKVEHSDLSFSKDWSFYLLYYTEFTPNEKDEYACRVSHVTFSTPKTVKWDRNI
What is the function of this protein?
Component of the class I major histocompatibility complex (MHC).  Involved in the presentation of peptide antigens to the immune system (By similarity).
What are the official names of this protein?
Beta-2-microglobulin.
What is the protein family that this protein belongs to?
Belongs to the beta-2-microglobulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSB1_YEAST
Sequence: MNGIQVDINRLKKGEVSLGTSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAIADIVQYHLELYTSQYGTPSTETAASVFKELCYENKDNLTAGIIVAGYDDKNKGEVYTIPLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDGSSGGVIRMVVLTAAGVERLIFYPDEYEQL
What is the function of this protein?
This subunit is necessary for the peptidylglutamyl-peptide hydrolyzing activity.
What are the official names of this protein?
Proteasome subunit beta type-1, Macropain subunit PRE3, Multicatalytic endopeptidase complex subunit PRE3, Proteasome component PRE3, Proteinase YSCE subunit PRE3.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TGT_SALHS
Sequence: MKFELDTTDGRARRGRLVFDRGVVETPAFMPVGTYGTVKGMTPEEVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIRKITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAKRSRDRFDSLGNKNALFGIIQGSVYEDLRDISVKGLVEIGFDGYAVGGLAVGEPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGVVKIRNAKHKSDTSPLDAECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRKAIEEGKLESFVTEFYQRQGRPVPPLNVD
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: LEUD_ECOL5
Sequence: MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLFNDWRFLDEKGQQPNPDFVLNFPQYQGASILLARENFGCGSSREHAPWALTDYGFKVVIAPSFADIFYGNSFNNQLLPVKLSDAKVDELFALVKANPGIHFDVDLEAQEVKAGEKTYRFTIDAFRRHCMMNGLDSIGLTLQHDDAIASYEEKQPAFMR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: Y2075_LISMC
Sequence: MENDRQAIVVWMNHLKQVRSLKRFGNVHYVSRKLKYAVLYCDMAEVEDISNKVSRFHYVKRVEMSFRPFLKTEYESKKEMMYEHKNEDVQISI
What are the official names of this protein?
UPF0298 protein Lm4b_02075.
What is the protein family that this protein belongs to?
Belongs to the UPF0298 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CATA_STAHJ
Sequence: MAKDDKRLTGLFGHPVSDRENSMTAGPRGPLLMQDAYFLEQMSHFDREVIPERRMHAKGSGAFGTFTVTNDITKYTNAKIFSEVGKQTEMFARFSTVAGERGAADLERDIRGFALKFYTEDGNWDLVGNNTPVFFFRDSKLFVSLNRAVKRDPRTNMRSPQNNWDFWTGVPEALHQVTILMSDRGMPKDFRHMHGFGSHTYSMYNDEGERVWVKYHFRTQQGIENYTDDEAAEIVGQDRESSQRDLYDAIENGDYPKWKMYIQVMTEEQAKNHPDNPFDLTKVWYKGDYPLIEVGEFELNRNPENYFMDVEQAAFAPTNIIPGLDFSPDKMLQGRLFSYGDAQRYRLGVNHWQIPVNQPKGVGIENMCPFSRDGQMRFLDGNQGGGPHYYPNNKGVYQSQPEYKKPAFPVDGDGYEYNQRQDDDNYFEQPGKLFRLQSDDAKERIFTNTANAMDGVSEDVKHRHIRHCYKADPEYGKGVAKALEIDINDVDLEGTNDETYENF
What is the function of this protein?
Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
Protein: TOF1_ASPFU
Sequence: MDEEGAPLSEGVQVVDPDVRAHVYSLVTALGGFNGESADRYVLGDDALACLRDIKRWLKLYDEKHNRMDVARCLGEANLVNGDLLPILTLWSTSGQKSKHMSRIALACLELLVPLTWPLEVHSEMTVNHHRHTPYLQQAQVLYKRGILSHGSGSILRTIIRIGLPSMAVPRSERTTRDEGILKLMLYFLRNIAVISPNARLAAEGDEEETSRSATINAFQNQDAFALLLTMCSNVGEDFSLQDVVLLEILFHIVKGVNVEKLFMNDAQRKAKRTDELGELLQKESSLRREYAKNAPTRHGRFGTMIWVKRDDAKVSTVSGQDVLKDSQTTLHKMDQSKKWNKPQIRRRAAEVTANNDFNTPVNINSTATKNLRMFVEEFLDSGFNPLFTHVRKAIEREADRVMDINTRQFFYTVAWFLEAERVRRAHQREKRHLGDTPLKEIEPDSFALVASVLNQETFVFLNRSMQYSYDNKDVEDLTAEMRCFTQILLTVQEMAQSPLEEDQEIADNIQNRIFYEETTHDRIVAIVRGYKDQGFGYLDACTELAHVFLRMLEHYSKENVDMHVRSRRRAKRKAKQAKQADIEGDDEEEASEEEDLMDVERISKERKFDFRRFAAKFCNQSCVDTFIAFTKYYRELNVDQLKRAHRYFYRIAFKQEMSVLLFRLDIINLFYRMIKGPGALDSNKPIFKEWEELVRQIIRRMIKKIDQRPALITELLFSKINSTVFYLEYGHEKQTISASKRPPAELEVEPREAKTIDEKIRIVVHVMVKDEHTDLVKWVSDVLNSAADEREAWESQEQHSGGQKAPNPMIPVKSDNESCQKAMFSNAKLRLLMSLVRFERLGMEDVPGASWVVPSSLNSQELRHTRSIIEQCLTEPVTENSDRDLSQLIRRKSGNNTRRDRDDQMANVDFGSDSEGDDNVPDGPLFPPNPRSRANALEQLKKQRKKRRKQAGEEEEPDEEDLEARRRARLENALARQAKIKSDLYIHASDEETDEEADQEFFRLEEQRRKEQAERIRKALLHGVVEEVSENSRKKSSGRKRQSDQYTASTADSQSKRQRRLQQTEGLDGNDDLVVAGTEARSPDSLGQGSPSLKGANDVEDTLVTSEENELDFDDDLAFSRNRTRDKVLSAENDDSDTEPPAPDTIDEDGEEAAAVAAPPRRRVRAGFVIESDSE
What is the function of this protein?
Forms a fork protection complex (FPC) with csm3 and which is required for chromosome segregation during meiosis and DNA damage repair.  FPC coordinates leading and lagging strand synthesis and moves with the replication fork.  FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors (By similarity).
What are the official names of this protein?
Topoisomerase 1-associated factor 1.
What is the protein family that this protein belongs to?
Belongs to the timeless family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FSLQ_DICDI
Sequence: MKNSFLINILIIYYLFIILFVNSQDLKLGGSCELIDSNSPCFSKLNYTNFYLQPGDSITQLNKNVSDIIRMLEFTTPECKPNAINIMCLKSYPKCETYNETLSNNTNIIFNLPSLPCNSICLKAETPCKIFIDNFIKDLSCNSNFSNGAPMFPINSTDYEFKESGNFNFNVECNDNIIYDNSSSVINCPAPLLNSKDHVIPGKTTYYYITDSCILDCPFEIYPGKTKILDRTNYTLTSISFITCIFMILTFGVLPNKITHRMESILSFACGGCITALSLFIQSRQDNFNCSSDPGRFKSQSDYLCLLTGLIFQFGAITSIFWSPMIAYDFYITSTLGKIRKFGLYRIVLWSFIFVLTALPAFGGKYSATVATNCWINSDDGSAWQYVSFYIPSWCAMGLICLFSILSVINVSKMYIQTPNNRILFFNIKILITLLLFLFVLTFASSLKFYMEERMDTYFDAIAVWVECIGKGDPSQCELHAPGYDLKALNIVVIGILGFTVFIGYGLDPIVIHIWMESKKFQWVLKKCRLDKIIKLNNSINNSNNNNNETASTSSGNERKQTTVKMSNLKSTEINQQP
What are the official names of this protein?
Frizzled and smoothened-like protein Q.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GREA_XANCP
Sequence: MRAPMTSKGAQRLREELDHLKSVKRPAVITAIAEARAHGDLKENAEYHAAREQQSFIEGRIKQLEGELSHAEIIDITKLAAGTKIVFGATVTLADTETDEEKRYQIVGDLEADIKLGLIAISSPLARALIGKLEGDSVTIDAPAGQREYEVVSVAYLD
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: HIS2_CANAX
Sequence: MIFPILPVISSPEDKQSIDEFSLVGQVLFPIESVSPKKHFIHQFPHDLDIFVNAIDNATTDQIVELLNVGIKQVFVNEKQYHDAIEAGSPSSRFVVAVDVPSTELLTSEASFVTSKPFSESDLKKYNANENRVIYIESNFTQDGAIELAKNYVPVIPSTKLTVKREEENKISISAVFVSTLTTDRPDGLYTTLITTPSPSYTALGIVYSSKDSIIAAIEEKVGVYQSRKRRDELWYKGKTSGATQKLVKLSKDCDSDVIQFMVEPRTGYGFCHRETKFTCFGDDIADSPARGLPKLDSTLQDRLENAPEGSYTKRLFDDEKLLIAKLKEELDELIEAKSKEEIAWECADLVYFAMVWCIKHGVRLADIEKNLDVKSLKVSRRKGDAKPQYQEAPVNSSYKLEIVSVDDAAAVERAMTRPVQKTADIMKLVLPIIEKVKSDGDKALIELTSKFDGVKLDAPVLQAPFPADLMDISEEMKAAIDLSMQNIEKFHAAQLPKEKVMTVETSPGVYCSRFAKPIENVGLYVPGGTAVLPSTAMMLGVPAKVAGCKNIIVASPPSRATGKLTPEVVYVAHKLGAKCIVMAGGAQAVTAMAYGTESVLKCDKILGPGNQFVTAAKMYVQNDTQALCSIDMPAGPSEVLVIADSNADADFVASDLLSQAEHGVDSQVILIGVGLSDEKLNEFQAAVERQAKVLPRKDIVAKCLAHSYILLAKTYKEAFDLSNQYAPEHLILQIDDAPSYVPDSIENAGSVFVGALSPESCGDYSSGTNHTLPTYGYARQYSGVNTATFQKFITSQEVTEKGLQNIGKAVMELARVEGLEAHRRAVEIRMERMAETK
What are the official names of this protein?
Histidine biosynthesis trifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the histidinol dehydrogenase family.
Protein: CCML_THEVB
Sequence: MKIARVCGTVTSTQKEDTLTGVKFLVLQYLGEDGEFLPDYEVAADTVGAGQDEWVLVSRGSAARHIINGTDKPIDAAVVAIIDTVSRDNYLLYSKRTQY
What is the function of this protein?
Probably forms vertices in the carboxysome, a polyhedral inclusion where RuBisCO (ribulose bisphosphate carboxylase, rbcL-rbcS) is sequestered.  Has been modeled to induce curvature upon insertion into an otherwise flat hexagonal molecular layer of CcmK subunits.
What are the official names of this protein?
Carboxysome shell vertex protein CcmL, Carbon dioxide concentrating mechanism protein CcmL.
What is the protein family that this protein belongs to?
Belongs to the CcmL/EutN family. CcmL subfamily.
What are the subcellular locations of this protein?
Carboxysome. Note=This cyanobacterium makes beta- type carboxysomes (Probable). Probably forms vertices in the carboxysome (Probable).
Protein: SLX1_CRYPI
Sequence: MKSNIQLHYCYFLLSEAKKKASYIGYSVNPCRRLRQHNGEIKKGAKKTKSGVPWNLGICVGGFPDRVAALRFEWAWQHPNICKVTRDNIESWKIVKTKKTSENKRILNKRQWSIQQRVSILLCMTTLEPWKNMNLTVFVFKDELENTIKEVIEGIKKIKISPNFTSPNILNKDYLLMFLYFGEDSFYEKGIKFLRCDYETFKEFQKPSFDCDSDSNIEDNSNVFNPEEIISHEDSFSIKCFLCQKDIGIGRNYLEFPCCTEIKVHLSCIQLWGESNNHLETVIDELFPLKEFVAPLIPLNISCPCCFKDFEWEEAKKNYIKTKNVPTESLELGEDFPVLSNGEKENYSQEENSQNKVIEDGFLEMDIDNHRNRLSYAHETKQKRDILFSDDEFSEISQKCEFIDLTVDSD
What is the function of this protein?
Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit SLX1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SLX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEU3_STAAW
Sequence: MTYNIVALPGDGIGPEILNGSLSLLEIISNKYNFNYQIEHHEFGGASIDTFGEPLTEKTLNACKRADAILLGAIGGPKWTDPNNRPEQGLLKLRKSLNLFANIRPTTVVKGASSLSPLKEERVEGKDLVIVRELTSGIYFGEPRHFNNHEALDSLTYTREEIERIVHVAFKLAASRRGKLTSVDKENVLASSKLWRKVVNEVSQLYPEVTVNHLLVDACSMHLITNPKQFDVIVCENLFGDILSDEASVIPGSLGLSPSASFSNDGPRLYEPIHGSAPDIAGKNVANPFGMILSLAMCLRESLNQPDAADELEQHIYNMIEHGQTTADLGGKLNTTDIFEILSQKLNH
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K1C15_HUMAN
Sequence: MTTTFLQTSSSTFGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGYGGGMRVCGFGGGAGSVFGGGFGGGVGGGFGGGFGGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQYFKTIEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMAGIAIREASSGGGGSSSNFHINVEESVDGQVVSSHKREI
What are the official names of this protein?
Keratin, type I cytoskeletal 15, Cytokeratin-15, CK-15, Keratin-15, K15.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: MURG_STRA3
Sequence: MGKKIVFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEHEQINQSGLDITFHSIATGKLRRYFSWQNMLDVFKVGVGVLQSIAIIAKLRPQALFSKGGFVSVPPVVAARLLKVPVFVHESDLSMGLANKIAYKFATIMYTTFEQSKDLIKTKHIGAVTKVMDCKKSFENTDLTSIKEAFDPNLKTLLFIGGSAGAKVFNDFITQTPELEEKYNVINISGDSSLNRLKKNLYRVDYVTDLYQPLMNLADVVVTRGGSNTIFELVAMKKLHLIIPLGREASRGDQLENAAYFEEKGYALQLPESELNINTLEKQINLLISNSESYEKNMSQSSEIKSQDEFYQLLIDDMAKVTKG
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MDTH_SALHS
Sequence: MSRVSQARNLGKYFLLIDNMLVVLGFFVVFPLISIRFVDQMGWAAVMVGIALGLRQFIQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFATMGIAHEPWLLWFSCFLSGLGGTLFDPPRSALVVKLIRPEQRGRFFSLLMMQDSAGAVIGALLGSWLLQYDFRLVCATGAILFILCALFNAWLLPAWKLSTVRTPVREGMRRVMSDKRFVTYVLTLAGYYMLAVQVMLMLPIMVNDIAGSPAAVKWMYAIEACLSLTLLYPIARWSEKRFRLEHRLMAGLLVMSLSMLPIGMVGNLQQLFTLICAFYIGSVIAEPARETLSASLADARARGSYMGFSRLGLAIGGAIGYIGGGWLFDMGKALAQPELPWMMLGIIGFITFLALGWQFSHKRTPRRMLEPGA
What are the official names of this protein?
Multidrug resistance protein MdtH.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: M3H91_BOMMX
Sequence: MNFKYIVAVSFLIASAYARSVQNDEQSLSQRDVLEEEESLREIRGIGGKILSGLKTALKGAAKELASTYLHRKRTAEEHEVMKRLEAVMRDLDSLDYPEEASERETRGFNQDEIANLFTKKEKRILGPVLGLVSNALGGLIKKIG
What is the function of this protein?
Maximin-H9 shows antimicrobial activity against bacteria and against the fungus C. albicans.  Shows strong hemolytic activity (By similarity).
What are the official names of this protein?
Maximins 3/H9 type 1.
What is the protein family that this protein belongs to?
Belongs to the bombinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ANMK_BURTA
Sequence: MQTGHPADGVYLGLMSGTSMDGVDGITVRFETGKPPAVLSEAFVGFADTLRDSLFALQQPGDDEIEREALAANALAARYAACCHEMLRAAGLSPDDVRALGVHGQTVRHRPERGYTRQINNAALLAELTRIDVIADFRSRDVAAGGQGAPLVPAFHATMFGSPDETRVVCNLGGISNITILPAARDGRDERNDAVRGHDCGPANALIDAWALRHLKRPFDEGGRFAARGTVDETLLAALLDEPYFRQSAPKSTGRDLFNADWLDAKLAGFRGLAPEDVQATLTALTAASVADEIARHAHDCRAVYVCGGGARNPVLLDALATALAARGLDAPVATTAALGVPPQQVESLAFAWLAYRFNARAPGNVSAVTGAAGERVLGALYPR
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: RIMO_ANADE
Sequence: MATRVYMHTLGCPKNRVDSEVMLGTLAEAGYRLVQDPAKAEVIVVNTCGFIESAKEESVEAIVELADQKREGRCRKLVVTGCLVQRHAEELARELPEVDHFLGTGAYQDVARIVSDAQAKRLVVPDPDFVHSAATPRVNSLPSHTAYLKIAEGCDNACAFCIIPKLRGGQRSRPIDDLVAEAAALAAQGTVELSLVAQDLTAYGQDLPGKVRLHHLLPELAKVDGLRWIRLHYAYPRDVPDALVAAMADEPKIVKYLDMPLQHSSDRLLRAMKRGRDSVFLRDLLARLRARIPGLALRTALIVGLPGETEADFEDLLRFVEEQRFERLGVFEYSPEEGTPAAEMADQVPDALKRERRDRIMAVQQGISRAHQQAMIGRRLEVLVEGRAEETEHLLAGRHAQQAPEIDGLTYVNDGVAYPGEIVTVEITDAAEYDLVGRVVARDPSRAARPLPAAPRPPPPRRKGGLNVLG
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_ECO5E
Sequence: MATYYSNDFRAGLKIMLDGEPYAVEASEFVKPGKGQAFARVKLRRLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGDNAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFVQIGEVIKVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BH154_ARATH
Sequence: MEYSRDSAEMMMETKRNVYSLEDNKIKRHKSSDLSFSSKERKDKLAERISALQQLVSPYGKTDTASVLLEGMQYIQFLQEQVKVLSAPYLQATPSTTEEEVEEYSLRSKGLCLVPLEYTSEVAQTNGADIWAPVKTPTSSHAFNLSSSNSPFQ
What are the official names of this protein?
Transcription factor bHLH154, BHLH transcription factor beta, bHLH beta, Basic helix-loop-helix protein 154, AtbHLH154, bHLH 154, bHLH transcription factor bHLH154.
What is the protein family that this protein belongs to?
Belongs to the bHLH protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CHNMO_DROME
Sequence: MDPQQQFCLKWNSFSSNLAITFSNLFKSDLLADVILSCDGVVFKAHKLILAACSKKFADLFENTPTNGQCVIILEATTPDNMAALLEFMYKGEVHVSQEALNSFLKSAESLQVKGLSTETGRLAAQQAQQHMGDLSPLDSPTGRRSVRNSLSGGSSSIVPGGVGIGLGGGATGANSMSGMGIGNGLSLAGMAAGGGMAAAANAAASSLSTLAASANIVDRCGSAGANIISGSAAGIGGSHSGGAGNGSGTVGIGGNGVGSGGGNNGPISLGSGAGAAHHLGGSTGILKQECDSLMHPGGSSSSSGMGYTHVPPIYRPINYEPPRKRAIVRSPYSEQEQRGSVLRDGSKSSECPSPINKPPYHRPSSSASSTAPTEADTMHSERASPQSSRYENHSPSTTAGNGNATSSLERIVKSERNNGSANEANDDDRELMDESTDNGAEDLRVKLENLKYSPPPPPNSNTSSTTPNTLLENLKADGTLSSNLAASIAPADMLNVWNATKMNNKNSVNTADGKKLKCLYCDRLYGYETNLRAHIRQRHQGIRVPCPFCERTFTRNNTVRRHIAREHKQEIGLAAGATIAPAHLAAAAAASAAATAAASNHSP
What is the function of this protein?
Required for morphological differentiation of postmitotic neurons during postembryonic brain development (PubMed:17055440).  Ensures production of appropriate neuron subtypes within a lineage by preventing precocious generation of late neuronal types of that lineage (PubMed:17055440).  Acts as a downstream mediator of the transcriptional activator Stat92e and is required for the development of the eye-antennal disk which gives rise to the adult eye, antenna and head capsule, for transcriptional repression of the Notch receptor ligand Ser and for the self-renewal of cyst stem cells in the testis (PubMed:20412771).  In the adult testis, maintains the male identify of adult somatic cyst stem cells (PubMed:25453558, PubMed:29389999).  Represses expression and alternative splicing of transformer pre-mRNA, resulting in the production of the male-specific isoform of transcription factor dsx which ensures male-specific transcription of target genes (PubMed:25453558, PubMed:29389999).  Plays a role in actin nuclear localization through its involvement in repressing the expression of the kinase Cdi (PubMed:26021350).  This maintains the cofilin/actin-depolymerizing factor homolog tsr in its unphosphorylated state which is required for actin nuclear import (PubMed:26021350).
What are the official names of this protein?
Zinc finger protein chinmo, Protein chronologically inappropriate morphogenesis.
What are the subcellular locations of this protein?
Nucleus.