PharMolix/UniProtQA huggingface dataset:
Protein: ZRP_ZYMMO
Sequence: MIDYRDRHILSLLQANAEMPLSEIAERVALSVSACSRRVARLREEGYIKGTIALLDRKKINLPTTIFLLVKTGLHTGNYLEQFHAAVSAIPEIVEVHRLTGNFDYILKLALPNVEYYDVIYKQILKHVAFYDMSAYISMETVKISPALPTNYI
What are the official names of this protein?
HTH-type transcriptional regulator Zrp, Global regulatory protein.
Protein: DPB3_KLULA
Sequence: MDEYKSKLPRIPISKCKKIARTDPEYILTSQAAFAATAFTTELFIQMLAEETCSLAQIHKQTKTLRLNYEDLSTAIRNLDKFQFLSDVVPQTENLASLVRENKVRYTIVNPSPEIDIESEDEVDEANEPEVGEPEVDEAEVEAEVEAEAAEPETHTLDEPRPESSS
What is the function of this protein?
As accessory component of the DNA polymerase epsilon (DNA polymerase II) participates in chromosomal DNA replication.
What are the official names of this protein?
DNA polymerase epsilon subunit C, DNA polymerase II subunit C.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYBH_AZOVI
Sequence: MALEKSLETGDGQEKVRKQTAVYVYEAPLRLWHWVTALSIVVLGVTGYFIGAPLPTMPGEAMDNYLMGYIRFAHFAAGYVLAIGFLGRVYWAFVGNHHARELFLVPVHRKAWWKELWHEVRWYLFLEKTPKKYIGHNPLGQLAMFCFFVVGAVFMSVTGFALYAEGLGRDSWADRLFGWVIPLFGQSQDVHTWHHLGMWYLVVFVMVHVYLAVREDIVSRQSLISTMVGGWRMFKDDRPD
What is the function of this protein?
Probable b-type cytochrome.
What are the official names of this protein?
Probable Ni/Fe-hydrogenase B-type cytochrome subunit.
What is the protein family that this protein belongs to?
Belongs to the HupC/HyaC/HydC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FLGK_BACSU
Sequence: MTSTFMGLETARRALSAQQAALSTTANNVANANTDGYTRQRVSLEATDYFPAVSKNAEKTAGQMGTGVQGKSVERIRDIFLDYQYRLQNNSAGYYDTKAKALSQMEGVLNETDDSGLNSVLNSFWNSLQELSNNTNEESARSVVARKGQAVAETFNYISESLTNVQSNLKAELNTTVLDVNSLLSQLNSLNKQIAQVEPVGLLPNGLYDQRDLLIDKLSSMVDIKVSYNKSGGNALASAEGTVSIEILDKNKQSLGTVLDGKNYEVSELAANYDNETGLVSSISIGDTAVQAESFSSKGSLLGFIESYGYITADGQEKGVYPEMLSDLDNMALEFAKAFNEVHRNGVTKSGEQGGDFFDFTGGETEPAKGAAGKIKVADSIIDSKGANIAFSLTGAANDNANATKLANVLTGKITINGKETSVLDYYAGLIGELGIEAQEANRLASNTETQLNDADINRQQMSAVSLDEEMTNMIQFQHAYNAAARMVTLQDELLDKVINGMGVGGR
What are the official names of this protein?
Flagellar hook-associated protein 1, HAP1.
What is the protein family that this protein belongs to?
Belongs to the flagella basal body rod proteins family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: ACT2_LUMTE
Sequence: MAEEDVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMNTASASSSLEKSYELPDGQVITIGNERFRCPEAMFHASFLGMESVGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMFPGIADRMQKEITALAPPTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin-2.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PG056_VACCC
Sequence: MLNRVQILMKTANNYETIEILRNYLRLYIILARNEEGHGILIYDDNIDSIMSMMNITRLEVIGLTTHCTKLRSSPPIPMSRLFMDEIDHESYYSPKTSDYPLIDIIRKRSHEQGDIALALEQYGIENTDSISEINEWLSSKGLACYRFVKFNDYRKQMYRKFSRCTIVDSMIIGHIGHHYIWIKNLETYTRPEIDVLPFDIKYISRDELWVRISSSLDQTHIKTIAVSVYGAITDNGPIPYMISTYPGNTFVNFNSVKNLILNFLDWIKDIMTSTRTIILVGYMSNLFDIPLLTVYWPNNCGWKIYNNTLISSDGARVIWMDAYKFSCGLSLQDYCYHWGSKPESRPFDLIKKSDAKRNSKSLVKESMASLKSLYEAFETQSGALEVLMSPCRMFSFSRIEDMFLTSVINRVSENTGMGMYYPTNDIPSLFIESSICLDYIIVNNQESNKYRIKSVLDIISSKQYPAGRPNYVKNGTKGKLYIALCKVTVPTNDHIPVVYHDDDNTTTFITVLTSVDIETAIRAGYSIVELGALQWDNNIPELKNGLLDSIKMIYDLNAVTTNNLLEQLIENINFNNSSIISLFYTFAISYCRAFIYSIMETIDPVYISQFSYKELYVSSSYKDINESMSQMVKL
What is the function of this protein?
Plays a role in intracellular enveloped virus (IEV) transport to the cell surface through microtubule transport.  Together with protein OPG064, forms a complex that interacts with host KLC2 (kinesin light chain isoform 2) to engage the kinesin-1 complex and thereby promote IEV trafficking.
What are the official names of this protein?
Protein OPG056, Protein F12.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG056 family.
Protein: Y1655_PASMU
Sequence: MLYHDTQSRVIAFRYLLMILKNLKIKIRTLAPNTPKSKPANEKLPAACAEPISRTSPNNQRPSDEPIIPMMIFINRPMSLFMTCSAIQPIKAPTIIAEIQPIFFSSMSSLYTKKLKSIHDFKKRKMIYKR
What are the official names of this protein?
Uncharacterized protein PM1655.
Protein: GLMS_CHLAB
Sequence: MCGIFGYLGSKLAIPVVLDGLAKLEYRGYDSAGLASIHLGDLFVRKTIGRVDELRHSLEQENIQSLLAIGHTRWATHGVPTVSNAHPHVDENRTCAVVHNGIIENFKELKSFLLSEGVSFSSDTDSEVIAQLFAYRYQTTADLIHSFSWTLSQLQGSFSCGLIHKDHPDVLLCAAQESPLILGLGEGENFIASDSRAFLKHTQSIQALASGELAIVGLGHEVETYNFALKRISKPVRQVTYTDAGSDKQGYSYYMLKEIYEQPEVLERLVHKYLDPQGHISEKFLQGFPLEDFDEISIVACGSSYHAGFLAKYIIESLVSIPVHVEVASEFRYRRAYIGQKTLAILISQSGETADTLAALKEFRRRQVSCVLGICNVEESALATGVDHCLFLEAGIEIGVASTKAFTAQLLLLILLGLKLTISKHTLSLTEHCACGKGLLELPELCNRLLANENLHSWAHTYCNEDRFIFLGRRLMYPICMEAALKLKEIAYVEANCYPAGEMKHGPIALISKGSPVITFCGDSTVYEKMVGCIMEVKARQAHVIAVASEAQEDIAAVSDFQIYVPNSHSLASPILYTIVGQIMAYTMALKKGNEIDCPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSRR_SALPB
Sequence: MQLTSFTDYGLRALIYMASLPDGRMTSISEVTEVYGVSRNHMVKIINQLSRAGFVTAVRGKNGGIRLGKPANTICIGDVVRELEPLSLVNCSSEFCHITPACRLKQALSKAVQSFLKELDNYTLADLVEENQPLYKLLLVE
What is the function of this protein?
Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress.  May require iron for activity.
What are the official names of this protein?
HTH-type transcriptional repressor NsrR.
Protein: FSLG_DICDI
Sequence: MKSIIFITFFIFFLKKLNGLPNGYGVGLVDPNGQCMNYIGDSIDQPLCKNKLSNNGEFIYSTIGNSLNSQTLSQQTIAKSFEALTFIQNQCQDLLFAEYGICNIYLSPCIITTVAPLKNISLPQRLCNSACQRMVTNCPRLGEKIDCSISFLFPEVGTLYNLSDYGYKANGGLYEVPCFNPTADYDNSSSLNEFIEICPSPLLLKNSSDPKYSKRGYTYLPPTNCVLPCPVPNYTKEKWNQIENLSKVLSTISFVCSIYNILSFGILKKKKTKYTICISALSASVALINLGDIIKIGVGYEKVLCPEPGRFATQVDDPLCGLTAALFHVGICSTVLWTTTMAIYLYSAIKNIKLFKFRYFIIFNTGFSLTSLIIAASASKFEAGTGSIECWIRDRWYSICLFWLPCGICLLIGTICIASVIVEIYKVSKNIKLSESETIMRQIKPIISVILVSGSFTYLFIIFFDIERNFGGYRSAVTDYVLCLLNSTDNGIECHTSGPSYNPYFMFYFFMRFFGILFFLIYGTSKNARDSWYELFIKIKVSLSETSSTISNNSGGGSSQQKQQQQNEIKLEKI
What are the official names of this protein?
Frizzled and smoothened-like protein G.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CTAA_LYSSC
Sequence: MQHNRYLKWFAVAATVGMLLILLGGALVTKTDSGLGCGRNWPDCNGSLIPKEITPEVLIEFSHRLVTGVVSISILVLTVWTWRKLGHIREVKLLGFLAMFFLIAQALIGAAQVLWGQGDFILALHFGISLISFAAVLLLSMIVFEVDRKFDADNVFIGKKLRWHTIAVTIYSYLVVYTGALVRHTDSSLICPDWPFCYNETPLASPNNMYEWVQMGHRLAVLIIFIWIAYITWHAVKEYKNQRVVYYGWIIAFTIVFLQVIAGMLVVLTKLNLTVALMHSLLISLLFGLLCYMIMLVARSNYNEKMK
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL19_CANLF
Sequence: MSMLRLQKRLASSVLRCGKKKVWLDPNETNEIANANSRQQIRKLIKDGLIIRKPVTVHSRARCRKNTLARRKGRHMGIGKRKGTANARMPEKVTWMRRMRILRRLLRRYRESKKIDRHMYHSLYLKVKGNVFKNKRILMEHIHKLKADKARKKLLADQAEARRSKTKEARKRREERLQAKKEEIIKTLSKEEETKK
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_STAS1
Sequence: MARIAGVDIPREKRIVISLTYVYGIGTTTANKIAEEANVSPETRVKDLTDDELGRIREIVDNYKVEGDLRREQNLNIKRLMEISSYRGIRHRRGLPVRGQKTKNNARTRKGPVKTVANKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: SPL2P_ARATH
Sequence: MSSPERALLNLLTDIALSFDGAILGLTLAVSAVGSALKYASTNAALKKIKDAPEVSISDLRSLLPASEDKSETNDNRKSNDQRIVVVRGVVKPKISGDEGYKNNNVLISPETGDKALIIQRTQTYVYSGWKRLFQSTGHRFMLERSLRKHGADFTRTVPFVIVGKDQQSNSSFVAVNMDGSRQPLPLTTVYNRLQPINSSFLQAFLYPDYPVGLLDIEKILPPGKDITAVGIYSFNNGVPEIKSCQDLPYFLSEMTKDKMIEDLMEQTNFIFLGSVILGIVSVGILSYAAVRTWNKWKQWNHQRELPQRPNDSVVDDEPEDADEIPDGELCVICVSRRRVPAFIPCGHVVCCRRCASTVERELNPKCPVCLQSIRGSMRVYYS
What is the function of this protein?
Possesses E3 ubiquitin-protein ligase activity.
What are the official names of this protein?
E3 ubiquitin-protein ligase SPL2, RING-type E3 ubiquitin transferase SPL2, SP1-like protein 2.
What are the subcellular locations of this protein?
Plastid, chloroplast outer membrane; Multi-pass membrane protein.
Protein: UREG_STAAT
Sequence: MANPIKIGIGGPVGAGKTQLIEKVVKRLSKEMSIGVITNDIYTKEDEKILVNSGVLPESRIIGVETGGCPHTAIREDASMNFAAIDELLERHDDIELIFIESGGDNLAATFSPELVDFSIYIIDVAQGEKIPRKGGQGMIKSDFFVINKTDLAPYVGASLEQMAEDTKVFRGKRPFTFTNLKTDEGLDEVIDWIERDTLLKGLS
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1357_MYCTO
Sequence: MDRCCQRATAFACALRPTKLIDYEEMFRGAMQARAMVANPDQWADSDRDQVNTRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCKAAQGWHFAKALPVDFFRE
What are the official names of this protein?
Uncharacterized protein MT1400.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOC_SHIF8
Sequence: MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRTGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAGEAPAAPQVTAEDASASLAELLNAGLGGSDNE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: ZSWM8_HUMAN
Sequence: MELMFAEWEDGERFSFEDSDRFEEDSLCSFISEAESLCQNWRGWRKQSAGPNSPTGGGGGGGSGGTRMRDGLVIPLVELSAKQVAFHIPFEVVEKVYPPVPEQLQLRIAFWSFPENEEDIRLYSCLANGSADEFQRGDQLFRMRAVKDPLQIGFHLSATVVPPQMVPPKGAYNVAVMFDRCRVTSCSCTCGAGAKWCTHVVALCLFRIHNASAVCLRAPVSESLSRLQRDQLQKFAQYLISELPQQILPTAQRLLDELLSSQSTAINTVCGAPDPTAGPSASDQSTWYLDESTLTDNIKKTLHKFCGPSPVVFSDVNSMYLSSTEPPAAAEWACLLRPLRGREPEGVWNLLSIVREMFKRRDSNAAPLLEILTDQCLTYEQITGWWYSVRTSASHSSASGHTGRSNGQSEVAAHACASMCDEMVTLWRLAVLDPALSPQRRRELCTQLRQWQLKVIENVKRGQHKKTLERLFPGFRPAVEACYFNWEEAYPLPGVTYSGTDRKLALCWARALPSRPGASRSGGLEESRDRPRPLPTEPAVRPKEPGTKRKGLGEGVPSSQRGPRRLSAEGGDKALHKMGPGGGKAKALGGAGSGSKGSAGGGSKRRLSSEDSSLEPDLAEMSLDDSSLALGAEASTFGGFPESPPPCPLHGGSRGPSTFLPEPPDTYEEDGGVYFSEGPEPPTASVGPPGLLPGDVCTQDDLPSTDESGNGLPKTKEAAPAVGEEDDDYQAYYLNAQDGAGGEEEKAEGGAGEEHDLFAGLKPLEQESRMEVLFACAEALHAHGYSSEASRLTVELAQDLLANPPDLKVEPPPAKGKKNKVSTSRQTWVATNTLSKAAFLLTVLSERPEHHNLAFRVGMFALELQRPPASTKALEVKLAYQESEVAALLKKIPLGPSEMSTMRCRAEELREGTLCDYRPVLPLMLASFIFDVLCAPGSRPPSRNWNSETPGDEELGFEAAVAALGMKTTVSEAEHPLLCEGTRREKGDLALALMITYKDDQAKLKKILDKLLDRESQTHKPQTLSSFYSSSRPTTASQRSPSKHGGPSAPGALQPLTSGSAGPAQPGSVAGAGPGPTEGFTEKNVPESSPHSPCEGLPSEAALTPRPEGKVPSRLALGSRGGYNGRGWGSPGRPKKKHTGMASIDSSAPETTSDSSPTLSRRPLRGGWAPTSWGRGQDSDSISSSSSDSLGSSSSSGSRRASASGGARAKTVEVGRYKGRRPESHAPHVPNQPSEAAAHFYFELAKTVLIKAGGNSSTSIFTHPSSSGGHQGPHRNLHLCAFEIGLYALGLHNFVSPNWLSRTYSSHVSWITGQAMEIGSAALTILVECWDGHLTPPEVASLADRASRARDSNMVRAAAELALSCLPHAHALNPNEIQRALVQCKEQDNLMLEKACMAVEEAAKGGGVYPEVLFEVAHQWFWLYEQTAGGSSTAREGATSCSASGIRAGGEAGRGMPEGRGGPGTEPVTVAAAAVTAAATVVPVISVGSSLYPGPGLGHGHSPGLHPYTALQPHLPCSPQYLTHPAHPAHPMPHMPRPAVFPVPSSAYPQGVHPAFLGAQYPYSVTPPSLAATAVSFPVPSMAPITVHPYHTEPGLPLPTSVACELWGQGTVSSVHPASTFPAIQGASLPALTTQPSPLVSGGFPPPEEETHSQPVNPHSLHHLHAAYRVGMLALEMLGRRAHNDHPNNFSRSPPYTDDVKWLLGLAAKLGVNYVHQFCVGAAKGVLSPFVLQEIVMETLQRLSPAHAHNHLRAPAFHQLVQRCQQAYMQYIHHRLIHLTPADYDDFVNAIRSARSAFCLTPMGMMQFNDILQNLKRSKQTKELWQRVSLEMATFSP
What is the function of this protein?
Substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex that promotes target-directed microRNA degradation (TDMD), a process that mediates degradation of microRNAs (miRNAs) (PubMed:33184234, PubMed:33184237).  The SCF-like E3 ubiquitin-protein ligase complex acts by catalyzing ubiquitination and subsequent degradation of AGO proteins (AGO1, AGO2, AGO3 and/or AGO4), thereby exposing miRNAs for degradation (PubMed:33184234, PubMed:33184237).  Specifically recognizes and binds AGO proteins when they are engaged with a TDMD target (PubMed:33184234).  May also act as a regulator of axon guidance: specifically recognizes misfolded ROBO3 and promotes its ubiquitination and subsequent degradation (PubMed:24012004).
What are the official names of this protein?
Zinc finger SWIM domain-containing protein 8.
What is the protein family that this protein belongs to?
Belongs to the ZSWIM8 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: ERG20_SCHPO
Sequence: MSAVDKRAKFESALPVFVDEIVNYLKTINIPDDVTEWYKNSLFHNTLGGKYNRGLSVIDSYEILLGHPLDEAAYMKAAVLGWMVELLQSFFLIADDIMDASKTRRGQPCWYLMPGVGNIAINDAFMVESAIYFLLKKHFRQESCYVDLIELFHDVTFQTELGQQLDLLTAPEDSVDLSKFSLQKHSFIVIYKTAFYSFYLPVALAMHLAGVATPENLKCAQDILIILGKYFQVQDDYLDCYGDPTVTGKIGTDILDNKCSWIINLALAKCTPEQRVILDDNYGRKDSESEKRVKAVFEELNIRGEFENYEESEVSEIKKLIDGVDESTGLKKSIFTTFLGKIYKRNK
What is the function of this protein?
Farnesyl pyrophosphate synthase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway (PubMed:17596513).  Fps1 catalyzes the sequential condensation of isopentenyl pyrophosphate with dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate (PubMed:17596513).  The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.  Activity by the mevalonate kinase erg12 first converts mevalonate into 5-phosphomevalonate.  5-phosphomevalonate is then further converted to 5-diphosphomevalonate by the phosphomevalonate kinase erg8.  The diphosphomevalonate decarboxylase mvd1 then produces isopentenyl diphosphate.  The isopentenyl-diphosphate delta-isomerase idi1 then catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).  Finally the farnesyl diphosphate synthase fps1 catalyzes the sequential condensation of isopentenyl pyrophosphate with dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate (Probable).
What are the official names of this protein?
Farnesyl pyrophosphate synthase, FPP synthase, FPS, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Geranyltranstransferase.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RLMM_SHESM
Sequence: MKNLFLFCRAGYEKECAAEIQQRAAELNVGGFVKANNNDAYVVYQCFEEDGGDTLVKQLPLDSLIFARQMFAASELLADLPESDRVSPIVAALSDVSKAGELRVETPDTNEAKELSAFCRKFTVPLRQHLKKSGSLLAQENPKRPIIHVCFIGPGRAYAGYSFSNNSSPYFMGIPRLKMAADAPSRSSLKLDEAFAQFVPKEEQEERVRSGMNAVDLGACPGGWTYQLVRRGMMVSAVDNGPMNEKLMETGQVKHFREDGFRFEPQRKNIYWLVCDMVEKPARVAELIEAWAINGWFKEAIFNLKLPMKSRYKEVMAILNTMQEILKENGINEFQLQCKHLYHDRDEVTVHLWIRPSQAWN
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_CITK8
Sequence: MQVLNSLRSAKQRHPDCQIVKRKGRLYVICKSNPRFKAVQGRKKRR
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: ETR2_CANTR
Sequence: MYSVLKQSIRPRLLATHNQFRTMITAQAVLYTQHGEPKDVLFTQSFEIDDDNLAPNEVIVKTLGSPINPSDINQIQGVYPSKPAKTTGFGTAEPAAPCGNEGLFEVIKVGSNVSSLEAGDWVIPSHVNFGTWRTHALGNDDDFIKLPNPAQSKANGKPNGLTINQGATISVNPLTAYLMLTHYVKLTPGKDWFIQNGGTSAVGKYASQIGKLLNFNSISVIRDRPNLDEVVASLKELGATQVITEDQNNSKEFGPTIKEWIKQSGGEAKLALNCVGGKSSTGIARKLNNNGLMLTYGGMSFQPVTIPTSLYIFKNFTSAGFWVTELLKNNKELKTSTLNQIIAWYEEGKLTDAKSIETLYDGTKPLHELYQDGVANSKDGKQLITY
What is the function of this protein?
Required for respiration and the maintenance of the mitochondrial compartment.  Oxidoreductase with a preference for short and medium chain substrates, including trans-2-hexenoyl-CoA (C6), trans-2-decenoyl-CoA (C10), and trans-2-hexadecenoyl-CoA (C16).  May play a role in mitochondrial fatty acid synthesis.
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase 2, mitochondrial, 2-enoyl thioester reductase 2.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FABA_SALPK
Sequence: MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMTETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPTARKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTAHDLKVGLFQDTSAF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3534_DICDI
Sequence: MYIQQSQIDVNSTMIKPLKNSNGISNSNINSFSIKNDIDSNINSNSNNIGNGNGNGNNSCNDHKNNNNNNNNRISPTLSSSSSSSSSHTTSPIIPSSKLNSNTTTSTTPTSTTSSTPTTPTITPSSPSVLYKNPMEFDNVFQFKEVLQRVLDSQFQSDWVAIIAKILGYILPNNDIVLRKCQNDEDVKELLSLLRPSSQLFRMIIENFTNDSFQFYFPFDRIPKCVIFDITIKNQSTPKIINQININQYKKDIVVNMFQYFFFAFGLFPDHLNLEMQLLPANLNNNNNNNNNNNSINNTLNSIENKFTRTIHGIPTFSANRQNSGNRLSSSTGFNSQRIFSGSSSSSSSGSSQTDNSLLFNYQQQQYMMSQKTKSIYLRLLSEYMDFFLPFQRSLIDGNLIIDPNRKLMVNHDMSLTFLKIITESLLGHNLLNQSLNILNQFNYSLLSSFKKPTPVYLSTIQTFITYFQCYSYTFNYLSPFSINSPPSSPSPSPITSNGNKSTTATATIIQPILMTPSLGLFFKQREIVSSGLFEYFVSYFERLDPNDQYLPIDKILNIWVGWLTPWDPNTRTSRRISPNVLQKNNKSTSSFQNLLNLTSSFTHSIGVVGNSGGNKNSNIGSASNLLVLNQEYYSKWENYVIEHYYFYSFIFNLLLIRSQSLDITSYLYIFKSILNIFNSPVLKSLLKRISKHDSIIVQQQEQQYQYQYQQQQQYHYQQPQFYQQSQQQQSQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQPQQPSQQQTPSVSSNYIDVSKDILLRLEYQIGFYQIREFINERNLFSELMVSNASRLVDILTLKINQQNQKDYLEVIKSLCTFYDFEEPIIKEKINNTTIINNNPNDINNANNSNNNNNNQSQVLLSPNRNKDGTLNDMGRKQIYDGKVICKPFDSNYPYEKLISQPLVFEKQPITSEEIGIIIKFGYMLTDNSQTRLFIRKLARKKLLFSLVLILAFIWFFFEIYFFFTRK
What are the official names of this protein?
Uncharacterized protein DDB_G0293534.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NHAA_HELP2
Sequence: MNLKKTENALSLTLKNFIKSESFGGIFLFLNAVLAMVVANSFLKESYFALWHTPFGFQIGDFFIGFSLHNWIDDVLMALFFLMIGLEIKRELLFGELSSFKKASFPVIAALGGMIAPGLIYFFLNADTPSQHGFGIPMATDIAFALGVIMLLGKRVPTALKVFLITLAVADDLGAIIVIALFYTTNLKFAWLLGALGVVLLLALLNRLNMRSLVPYLLLGVLLWFCVHQSGIHATIAAVVLAFMIPVKIPKDSKNVELLELGKRYAETSSGALLTKEQQEILHSIEEKASALQSPLERLEHFLAPISGYFIMPLFAFANAGVSVDSSINLEVDKVLFGVILGLCLGKPLGIFLITFISEKLKITARPKGISWWHILGAGLLAGIGFTMSMFISNLAFTSEHKDAMEVAKIAILLGSLISGIIGALYLFALDKRAALKK
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CARA_ASPFU
Sequence: MFARVFKAMPARASALTSVNASIPARFMATVRQQRPAHERATFTIRDGPIFHGKSFGARTNISGEAVFTTSLVGYPESLTDPSYRGQILVFTQPLIGNYGVPSAERDEHGLLKYFESPNLQAAGVVVADVAEQYSHWTAVESLGEWCAREGVPAISGVDTRAIVTYLRERGSSLARITVGEEYDADQDEAFTDPEQIHLVRQVSTKAPFHVSAADPQCHVAVIDCGVKENILRSLVSRGAGITVFPFDYPIHKVAHHFDGVFISNGPGDPTHCQETTYHLRRLMETSQVPIFGICLGHQLLALAAGARTIKLKYGNRAHNIPALDLSTGRCHITSQNHGYAVDASTLPSDWKPYFVNLNDSSNEGMIHKSRPIFSTQFHPEAKGGPLDSSYLFDIYIDSVKKYKASQAAFYPQRDSLPSPLLVDLLAKERVGVQPTIGMQNIAAAATAAAAAA
What are the official names of this protein?
Carbamoyl-phosphate synthase arginine-specific small chain, CPS-A, Arginine-specific carbamoyl-phosphate synthetase, glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
What are the subcellular locations of this protein?
Cytoplasm.