PharMolix/UniProtQA huggingface dataset:
Protein: AKTIP_XENTR
Sequence: MNPFWNMSSAAVRKRSDNDEKIATGDQKISPPRSSSAKKQLPSIPKNAVPITKPISPSPSVQPTNGTHASYGPFYLEYSLLAEFTLVVKQKLPGVYVQPSYRSALMWFGVIFIRHGLYQDGVFKFTVYIPDNYPDGECPRLVFDVPVFHPLVDPVSGELDVKRAFTKWRRNHNHIWQVLMYARRIFYKIDTTSPLNPEAAVLYEKDVQLFKSKVVDSVKLCNSHLFDQPKIEDPYAIIFSPWNPVLHDDARERMLAQKKSEEQSKGLHVSGLSWVKPGSVLPFSKEENSLQT
What is the function of this protein?
May function to promote vesicle trafficking and/or fusion.  May also regulate apoptosis (By similarity).
What are the official names of this protein?
AKT-interacting protein, Fused toes protein homolog.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. FTS subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: MANBA_ASPNC
Sequence: MRHSIGLAAALLAPTLPVALGQYIRDLSTEKWTLSSRALNRTVPAQFPSQVHLDLLRAGVIGEYHGLNDFNLRWIAAANWTYTSQPIKGLLDNYDSTWLVFDGLDTFATISFCGQQIASTDNQFRQYAFDVSTALGSCKGDPVLSINFGSAPNIVDAIAQDSNSQKWPDDVQLTYEYPNRWFMRKEQSDFGWDWGPAFAPAGPWKPAYIVQLDKKESVYVLNTDLDIYRKGQINYLPPDQSQPWVVNASIDILGPLPTKPTMSIEVRDTHSGTILTSRTLNNVSVAGNAITGVTVLDGLTPKLWWPQGLGDQNLYNVSITVQSRGNQTVASVNKRTGFRTIFLNQRNITEAQRAQGIAPGANWHFEVNGHEFYAKGSNLIPPDSFWTRVTEEKMSRLFDAVVVGNQNMLRVWSSGAYLHDYIYDLADEKGILLWSEFEFSDALYPSDDAFLENVAAEIVYNVRRVNHHPSLALWAGGNEIESLMLPRVKDAAPSSYSYYVGEYEKMYISLFLPLVYENTRSISYSPSSTTEGYLYIDLSAPVPMAERYDNTTSGSYYGDTDHYDYDTSVAFDYGSYPVGRFANEFGFHSMPSLQTWQQAVDTEDLYFNSSVVMLRNHHDPAGGLMTDNYANSATGMGEMTMGVVSYYPIPSKSDHISNFSAWCHATQLFQADMYKSQIQFYRRGSGMPERQLGSLYWQLEDIWQAPSWAGIEYGGRWKVLHHVMRDIYQPVIVSPFWNYTTGSLDVYVTSDLWSPAAGTVDLTWLDLSGRPIAGNAGTPKSVPFTVGGLNSTRIYGTNVSSLGLPDTKDAVLILSLSAHGRLPNSDRTTNLTHENYATLSWPKDLKIVDPGLKIGHSSKKTTVTVEATSGVSLYTWLDYPEGVVGYFEENAFVLAPGEKKEISFTVLEDTTDGAWVRNITVQSLWDQKVRG
What is the function of this protein?
Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of beta-mannosidic oligosaccharides of various complexity and length.  Involved in the degradation of polymeric mannan and galactomannan (By similarity).
What are the official names of this protein?
Beta-mannosidase A, Mannanase A, Mannase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family. Beta-mannosidase A subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ITR4_CUCSA
Sequence: MMCPRILMKCKHDSDCLPGCVCLEHIEYCG
What is the function of this protein?
Inhibits trypsin.
What are the official names of this protein?
Trypsin inhibitor 4, CSTI-IV, Trypsin inhibitor IV.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I7 (squash-type serine protease inhibitor) family.
What are the subcellular locations of this protein?
Secreted.
Protein: GH38_ORYSI
Sequence: MAVMTDVSTTGTALRTPAAGAVKEGDVEKLRFIDEMTTNVDAVQERVLGEILGRNAGTEYLTKCGLDGATDRAAFRAKVPVVSYDDLQPYIQRIANGDRSPILSTHPVSEFLTSSGTSAGERKLMPTIMDELDRRQLLYSLLMPVMNLYVPGLDKGKGLYFLFVKSETKTPGGLTARPVLTSYYKSDHFKNRPYDPYHNYTSPTAAILCADAFQSMYAQMVCGLCQRNDVLRLGAVFASGLLRAIRFLQLNWEQLADDIESGELTPRVTDPSVREAVAAILLPDPELAKLIRAECSKGDWAGIITRVWPNTKYLDVIVTGAMAQYIPTLEFYSGGLPMACTMYASSECYFGLNLRPMCDPSEVSYTIMPNMGYFEFLPVDETGAASGDATQLVDLARVEVGREYELVITTYAGLNRYRVGDVLRVTGFHNAAPQFRFVRRKNVLLSIESDKTDEAELQRAVERASALLRPHGASVVEYTSQACTKRIPGHYVIYWELLTKGAGATVVDADTLGRCCLEMEEALNTVYRQSRVADGSIGPLEIRVVRPGTFEELMDYAISRGASINQYKVPRCVTFPPIVELLDSRVVSSHFSPALPHWTPARRSE
What is the function of this protein?
Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excessive free auxin (PubMed:18192436).  Produces more IAA-Asp levels than IAA-Ala levels in vitro (PubMed:18192436).  May participate in the activation of disease resistance by preventing the accumulation of free IAA, which reduces the expression of a group of auxin-responsive genes encoding expansins that control cell wall loosening and expansion (PubMed:18192436).  Contributes to late events in stamen and carpel differentiation, and influences floret fertility (PubMed:22016342).
What are the official names of this protein?
Indole-3-acetic acid-amido synthetase GH3.8, Auxin-responsive GH3-like protein 8, OsGH3-8.
What is the protein family that this protein belongs to?
Belongs to the IAA-amido conjugating enzyme family.
Protein: RUVA_BIFLS
Sequence: MIGMLTGRVESVETDTALIDVGGVGYETRMPATDLGRLHAGQDACVFTYLNLSQDSVTLYGFLDRDSKRVFLQLIKVSGIGPKVAQSLLGTMTPSQLARAIADNDAAALAKAPGLGRKGAQKIILELKGSVDLNQSDDASAGNAPYQPTVDAGVEQVVEGLVSLGWRQQDAQRAVNEACAENDVPMPLASDDAPRVLRLALARMDRGR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: NADD_SACEN
Sequence: MSRRRRIGVMGGTFDPIHHGHLVAASEVQAQFGLEQVIFVPTGQPWQKTHEVVSPAEDRYLMTVVATASNPRFQVSRVDIDRAGPTYTADTLADLRALYPEAELYFITGADALEQILSWHRVDELFELAHFIGVTRPGYQLAGEHLPKGAVSLVEIPAMAISSTGCRQRVRAGLPVWYLVPDGIVQYIAKRGLYRGEDDSAGVEWGPRPSGT
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: GL120_ARATH
Sequence: MRVSQSLVPFAIIALVLSFVNAYDPSPLQDFCVAIDDLKGVFVNGRFCKDPKRVDAKDFFFSGLNVPGNTNNQVGSNVTTVNVDQIPGLNTMGISLVRIDYAPHGQNPPHTHPRGSEILVLVEGTLYVGFVSSNQDNNRLFAKVLHPGDVFVFPIGMIHFQVNVGKIPAVAFAGLSSQNAGVITIANTVFGSNPPIYPELLARAFQLDASVVKELQAKFGSI
What is the function of this protein?
May play a role in plant defense.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Germin-like protein subfamily 1 member 20, GLP2a copy 2, GLP2b, Germin type 2, At-GERM2, AtGER2.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: DEOD_YERPP
Sequence: MATPHINAEMGDFADVVLMPGDPLRAKFIAETFLQDVREVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYAKELITDFGVKKIIRVGSCGAVRTDVKLRDVVIGMGACTDSKVNRMRFKDHDYAAIADFEMTRNAVDAAKAKGVNVRVGNLFSADLFYTPDPQMFDVMEKYGILGVEMEAAGICGVAAEFGAKALTICTVSDHIRTGEQTTAAERQTTFNDMIEIALESVLLGDNA
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: ASR1_ASHGO
Sequence: MLKHISSHIAMGCPQDECSICWESMPSGVGRLMPCGHEYHLACIRKWFHLHSGNRSCPVCRTEASVLVDTDHEVKIDLSVGQLLDFYGLLDEIGSQLLAITLQDHSTQDDEVNEEGLAEQRAQLTLVQCGICGEMNGDIDTCCNRCHHMYHHSCLGQLLVEVNAEREQGWSHCIFCYEQLVPLYISGARRVLSLQDRGVHRGRVRNNRSILTELIYERSGVLVHGIEDQHASQHDINDIEHSWHLLEQNRQRKQLEYQDKCKIQAHVRRILDHYYHCAKVTKAQYTFINKKVSQTLYALSRGVYPAVDLDYDGIAKTLILDEMEKLSS
What is the function of this protein?
Required for tolerance to alcohol.
What are the official names of this protein?
Alcohol-sensitive RING finger protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Accumulates in the nucleus specifically upon alcohol stress.
Protein: TDXH_SACS2
Sequence: MSEERIPLIGERFPEMEVITTQGRIKLPDDYKGRWFVLFSHPGDFTPVCTTEFYSFAKKYEEFKKLNTELIGLSVDSNISHIEWIMWIEKNLKVEIPFPIIADPMGNVAKRLGMIHAQSSTATVRAVFVVDDKGVVRLILYYPMEIGRNIDEILRAIRALQLVDKAGVVTPANWPNNELIGDKVINPAPRTIKDAKMRLGQPFDWWFTYKEVKTT
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Peroxiredoxin, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Prx6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGLRA_ASPNC
Sequence: MPSAKPLFCLATLAGAALAAPAPSRVSDFTKRSTCTFTDAATASESKTSCSDIVLKDITVPAGETLNLKDLNDGTTVTFEGTTTWEYEEWDGPLLRISGKDITVTQSSDAVLDGNGAKWWDGEGTNGGKTKPKFFYAHDLDDSKISGLYIKNTPVQAISVESDNLVIEDVTIDNSDGDSEGGHNTDGFDISESTYITITGATVKNQDDCVAINSGENIYFSGGTCSGGHGLSIGSVGGRDDNTVKNVTFIDSTVSDSENGVRIKTVYDATGTVEDITYSNIQLSGISDYGIVIEQDYENGDPTGTPSNGVTISDVTLEDITGSVDSDAVEIYILCGDGSCSDWTMSGIDITGGETSSDCENVPSGASCDQ
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.  Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall (By similarity).
What are the official names of this protein?
Probable endopolygalacturonase A, Pectinase A, Polygalacturonase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: YL49A_YEAST
Sequence: MCMLSWFISTSPLKEYCGGKRNLQRNNF
What are the official names of this protein?
Putative uncharacterized protein YLR149C-A.
Protein: THII_BACHK
Sequence: MMTYEYILVRYGEMTTKGKNRSKFVSTLKDNVKFKLKKFPNIKIDATHDRMYIQLNGEDHEAVSERLKDVFGIHKFNLAMKVPSELEDIKKGALAAFLQVKGDVKTFKITVHRSYKHFPMRTMELLPEIGGHILENTEDITVDVHNPDVNVRVEIRSGYSYIMCDERMGAGGLPVGVGGKVMVLLSGGIDSPVAAYLTMKRGVSVEAVHFHSPPFTSERAKQKVIDLAQELTKYCKRVTLHLVPFTEVQKTINKEIPSSYSMTVMRRMMMRITERIAEERNALAITTGESLGQVASQTLDSMHTINEVTNYPIIRPLITMDKLEIIKIAEEIGTYDISIRPYEDCCTVFTPASPATKPKREKANRFEAKYDFTPLIDEAVANKETMVLQTVEVVAEEEKFEELF
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARP3_TAKRU
Sequence: MAGRLPACVVDCGTGYTKLGYAGNTEPQFIMPSCIAIKESSKVGDQAQRRMMRGVDDLDFFIGDEAIDKPPYATKWPIRHGIVEDWDLMERFMEQIIFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFTQQLLREREVGIPPEQSLETAKAVKERFSYVCPDLVKEFNKYDTDGSKWIKQYTGINAITKKEFTIDVGYERFLGPEIFFHPEFANPDFTQPISEVVDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKMSEELSGGKLKPKPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKKDYEEIGPSICRHNPVFGVMS
What is the function of this protein?
ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF).  The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (By similarity).  Seems to contact the pointed end of the daughter actin filament (By similarity).  In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (By similarity).  The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (By similarity).
What are the official names of this protein?
Actin-related protein 3, Actin-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection. Nucleus.
Protein: CAPS1_PFV2
Sequence: MSVVTTRARIAETLTEKHTLGIEKVVATDSWRVGITSREKKLERINISAEISRRIQDEAIAYARNKGIPYLPGINGIAWKLLRLKWLGYTDQINVVMRTVPAEWRDFLTQIMENTQMESMYSELRKVRV
What is the function of this protein?
Self-assembles to form a helical, filamentous nucleocapsid mesuring 400 nm in length and 20 nm in width (Probable) (PubMed:32368353).  Together with capsid protein 2, wraps arounds the DNA and maintains it in an A-form (Probable).  Capsid proteins probably maintain the DNA in A-form by non-specific desolvation and specific coordination of the DNA phosphate groups by positively charged residues (Probable).  This certainly protects the viral DNA under conditions such as the extreme desiccation of its host (Probable).
What are the official names of this protein?
Major capsid protein 1, MCP1, Major capsid protein VP1.
What are the subcellular locations of this protein?
Virion.
Protein: RODZ_SALTI
Sequence: MNTEATHDQNEAQTTGVRLRNAREQLGLSQQAVAERLCLKVSTVRDIEEDKAPSDLASTFLRGYIRSYARLVHVPEEELLPGLEKQAPLRAAKVAPMQSFSLGKRRKKRDGWLMSFTWLVLFVVVGLTGAWWWQNHKAQQEEITTMADQSTAELNADKDSGQSVPLDTSAATSQDTTPAQTAPAPATPVDSTAATQNTVVAPSQANVDTAATSAAPAATETPSALPTSQAGVAAPAADPNALVMNFTADCWLEVTDATGKKLFSGMQRKDGNLNLTGQAPYKLKIGAPAAVQIQYQGKPVDLSRFIRTNQVARLTLNAEPTPAQ
What is the function of this protein?
Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
What are the official names of this protein?
Cytoskeleton protein RodZ.
What is the protein family that this protein belongs to?
Belongs to the RodZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Forms helical filaments along the long axis of the cell.
Protein: RRF_MYCCT
Sequence: MTDLILKNAELQMKETIDAYVIHLRQIRTGKASGAILDKVMVNYYGSLMPLNQISQITTPEPNLIIIKPYDRNVITEAVGAIHKADLGLNPISDATLIRIPIAPLTEDVRKNLVKKVHKELEGYKIRIRNIRRDAIDEIKKVENISKDLISDNEDKIQQITDKFIKQLDDLTKEKERELMTI
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIF_DROME
Sequence: MFEEAFGDIQEIINASMELNGGATGGGSVAGAVGGGGAAHHILSQSTSLPVMPSHIPLHLQNQNMNQNLPEPSARSGPHLRIVEEPTSNIIRFRYKCEGRTAGSIPGMNSSSETGKTFPTIEVCNYDGPVIIVVSCVTSDEPFRQHPHWLVSKEEADACKSGIYQKKLPPEERRLVLQKVGIQCAKKLEMRDSLVERERRNIDPFNAKFDHKDQIDKINRYELRLCYQAFITVGNSKVPLDPIVSSPIYGKSSELTITRLCSCAATANGGDEIIMLCEKIAKDDIEVRFYETDKDGRETWFANAEFQPTDVFKQMAIAFKTPRYRNTEITQSVNVELKLVRPSDGATSAPLPFEYYPNPELLTKHNRRVAQKTVESLKRSLMSTNLHPSKQVKTSSQYTIFSKPQIATTTPQTQVSPGMPLMFPGGSPNFVQDIKMENGFMDVDSQSSQCPSVERNFASPRSNCSTVDSIPPMQMGQNQTHLYLPDATNFTFNGNFASPSSNCSTVDSIPPFQIGQRNNHMYLPENSNFPVNGCSPTHFSGGSMTPINNNNNVLINNNNNDFLSQKMSAISIPPQGNFGIKQVYQQTQQFLPQLQPESIPYLAQSHPEQSQYQQQQQPQEQQPPADEPTQSFSDLISSSIGMAPIDTSELIQDIEAELNSLGIQPFK
What is the function of this protein?
Mediates an immune response in larvae (PubMed:8242747).  DIF binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of the immunity gene CECA1 (PubMed:8242747).  Involved in the melanization immune response to bacterial challenge, possibly by acting in a Toll signaling pathway that down-regulates Spn27A in response to infection (PubMed:12456640).  Part of a signaling pathway involving NF-kappa-B (rel) and Toll-related receptors, that functions in the apoptosis of unfit cells during cell competition (PubMed:25477468).  May be part of a NF-kappa-B and Tollo signaling cascade that regulates development of the peripheral nervous system (PubMed:18000549).
What are the official names of this protein?
Dorsal-related immunity factor Dif.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Accumulates in the nucleus upon bacterial infection or injury.
Protein: BSHC_CARHZ
Sequence: MRYEEINLGYEKNLVRYYLTGYDRVAKFYHYNPWNTRSFYDRADYLKDKSNPEALYNLLSFYLKDFALDQKVVENLDKIKKGAFIVLTGQQPGFLTGPLYTIYKAVHAIIEAKRLSELLNHEVVPLFWIGSEDHDVEEVNFLYFPGKEGPQEIKIEFTDLRKIPAGLRPAEPETVEAIEKFEGLLPNFDYKEEVFTEIKKAYHSANLGQAFARLMLKLFGKFGLLVYDGLNPEFKRVTKGYLKNAFLKRDAIEKALFKVYTEQQSLGIEPQLDPCPNHCNMFIFKNDERIALEVAGEKVVSRDGEVSFTREEFLEFMERYPEKLSPNLVVRTSIQSLVFPVLAYVAGPGEIGYYGMLKEVYEIMGTQMPVILPRFTATLIEPRVEKALKEFALLPQEIYQDYDGVFHRVLERLDNLGIDDTFKALKESINSAYKNLQEKLAPLGADFQKLTGENLGRVMAQVKYLEERAQKYHREKNSKYIEKLWYLKTNFLPENEWQERVYNVFYYLAKYGFALIEKLLGIPFNPGKHYLLYLE
What is the function of this protein?
Involved in bacillithiol (BSH) biosynthesis.  May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.
What are the official names of this protein?
Putative cysteine ligase BshC.
What is the protein family that this protein belongs to?
Belongs to the BshC family.
Protein: ORF5_HAPV1
Sequence: MIQSLLLDLLPIRSFVMLALVVVGLQLVGVDVIGPAIDMARNFMLDTFSVSDLGSLV
What are the official names of this protein?
Uncharacterized protein 5.
Protein: FOLC_CRIGR
Sequence: MSWARTHLRSALSLAAVSARGATTEGAARRWLSAWPAPQEPGMEYQDAVRMLNTLQTNASYLEQVKRQRSDPQAQLEAMEVYLARSGLQVEDLNQLNIIHVTGTKGKGSTCAFTERILRSYGLKTGFFSSPHLVQVRERIRINGKPISPELFTKHFWRLYHQLEEFKDDSHVAMPAYFRFLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGMDHTSLLGDTVEKIAWQKGGIFKPGVPAFTVLQPEGPLAVLRDRAQQTSCPLYLCPPLEALEDGGLPLTLGLEGEHQRSNAALALQLAHCWLEQQDHQDIRELKVSRPSMRWQLPLAPVFHPTSHMRHGLRDTEWPGRTQVLRRGPLTWYLDGAHTTSSVQACVRWYCQSLQRSKHPSGGPEVYVLLFNSTGDRDSAALLKLLQPCQFDYAVFCPNLTEVSSTENADQQNFTVTLDQVLLRCLQHQQHWSCLSEKQASPDFLSSPSPEPGRPGSLQPALRPPHSTGTNSLVFSCISHALQWISQGRDPIFQAPSPPRSLLSHPTASSGASILREAGAIHVLVTGSLHLVGGVLKLLEPSLSQ
What is the function of this protein?
Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.
What are the official names of this protein?
Folylpolyglutamate synthase, mitochondrial, Folylpoly-gamma-glutamate synthetase, FPGS, Tetrahydrofolate synthase, Tetrahydrofolylpolyglutamate synthase.
What is the protein family that this protein belongs to?
Belongs to the folylpolyglutamate synthase family.
What are the subcellular locations of this protein?
[Isoform 1]: Mitochondrion inner membrane. Mitochondrion matrix. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
Protein: TM212_MOUSE
Sequence: MKGLYQAAGRTLVTLGGLSIFSGAIAFFPVFSCKLWYTGWSVWIACPIWNGALAVTAGSLVLLAHREWTQRHLWEAVFTFVILSILGCPLHFTVALQSALLGPYCFYSFSGVAGTNYLGYVVTFPFPYTKFPSVCVDPLHYEEYHLTLQVLDLCLSLILFCVSLAVFIKLSARLMQTGYINGPENPQ
What are the official names of this protein?
Transmembrane protein 212.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BIOD_CELJU
Sequence: MSKKAFFITGTDTDAGKTLVATGLLAAARLRGLSTLGLKPVAAGCTRTEQGLRNSDALALQAQSTLPVVYEQVNPVALEAAIAPHIAALQEKRSLSADRLAGFCRSSLRQADFTLVEGAGGWRVPLNPSETLANLAQLLRLPVVLVVGMRLGCINHALLTVEAIRNDGLPLVGWVANVLDADMPVLEENIASLAQRIPAPCLGVVPRLSMASADAASAHLDLTPLLDA
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIG_VIBVU
Sequence: MTKTQNVDPNEIKKFEDMASRWWDLEGEFKPLHQINPLRLDYVLSKADGLFGKKVLDVGCGGGILAESMAKEGAVVTGLDMGKEPLEVARLHALETGTKLTYIQSTIEDHAAENAQMYDVVTCMEMLEHVPDPLSVIRSCAALVKPGGHVFFSTLNRNIKSYLFAIVGAEKLLKIVPEGTHDHDKFIRPSELIKMIDQTDLCEQGITGLHYNPLSDTYKLGRNVDVNYIVHTQKF
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: DINIR_ECOLX
Sequence: MRIEIMIDKEQKISQSTLDALESELYRNLRPLYPKTVIRIRKGSSNGVELTGLQLDEERKQVMKIMQKVWEDDSWLH
What are the official names of this protein?
DinI-like protein in retron Ec67, Protein ORFf in retron Ec67.
What is the protein family that this protein belongs to?
Belongs to the DinI family.
Protein: RSSA_DEBHA
Sequence: MSLPGSFDLTPEDAKLLLAANVHLGSKNVQVHNKPYVYKTRPDGVNVINVGKTWEKIVLAARIIAAIPNAADVAVCSTRTFGQRAVLKFAAHTGATPIAGRFTPGNFTNYITRSFKEPRLVVVTDPRTDFQAIKESSYVNIPVIALTDMDSPSEYVDVAIPCNNKGKHSIGLIWWLVAREVLRLRGIIPDRTTEWSVMPDLYFYRDPEEIEQNATEDIKTDDVEEAPAADAETEWTGETEEVDWAESGATPAAEEAAASNW
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein S0.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXT_STRGG
Sequence: MSDTPVIGVLALQGDVREHLIALASADALARPVRRPEELAEVDGLVIPGGESTTMSKLAVLFGMMEPLRERVRAGMPVYGTCAGMILLAEKILDPRSGQETVGGIDMIVRRNAFGRQNESFEAAVEVGGVEGGPVDGVFIRAPWVESVGARTEVIAEHGGHIVAVRQENALATSFHPELTGDHRVHALFVDMVRAVN
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: PHNC2_RHOPA
Sequence: MGAEWLPVRKLGMVRGISPDSNLIRIDGISVRRGHRTVLHDVTASFPTAKVTAIVGPSGVGKTTMLGLLNGLIAPASGTVSFSEIGLLTEPTALRAARHQTATIFQDHALIGRLSAIDNVLLGLADTRHPLSPLPWPVAARQRAAKALDDVGLLDLATRRTAQLSGGERQRVGVARALIRRPKLLLGDEPFASVDPALAQQLGGLFRSLAMREGLTVILVLHQLQLARAIADRIIGLSDGRVAFDGPAAAFDADLEARIFPSLALSHDHSPPLSQPKETICSID
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.