PharMolix/UniProtQA huggingface dataset:
Protein: COBT_ECO5E
Sequence: MQTLANLLNTIPAIDPAAMSRAQRHIDGLLKPVGSLGRLEALGVQLAGMPGLNGIPHVGKKAVLVMCADHGVWEEGVAISPKEVTAIQAENMTRGTTGVCVLAAQAGANVHVIDVGIDTAEPIPGLINMRVARGSGNIASAPAMSRRQAEKLLLDVICYTRELAKNGVTLFGVGELGMANTTPAAAIVSTITGRDPEEVVGIGANLPTDKLANKIDVVRRAITLNQPNPQDGVNVLAKVGGFDLVGMAGVMLGAASCGLPVLLDGFLSYAAALAACQMSPAIKPYLIPSHLSAEKGARIALSHLGLEPFLNMDMRLGEGSGAALAMPIIEAACAIYNNMGELAASKIVLPGNTTSDLNS
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: CASP2_RAPSA
Sequence: MKNESTFIDVPADSSSAMKGKAPLIGVAKDHTASGSGGYNRGLSIFDFLLRLAAIVAASVAAGTMFTSDETLPFFTQFLQFEAGYDDLPTFQFFVIAMSLVSGYIVLSLPISVVTIVRPLAAAPRLLLLVLDTAVMGLTMAAASSAAAISYVAHNGNQNTNWLPICQQFFDFCQKTSGAVVSSFVAVVFFMILVVLSGVALERH
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 2, RsCASP2.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: RECR_BURCJ
Sequence: MKQPSALSALVEALRVLPGVGPKSAQRMAVHLMQHDREGAERLGRSLLFATEHLQHCEKCNTFTEAQICEVCSDEERDPTLLCVVETPADQIMLEQTMTYRGLYFVLMGRLSPLDGIGPKEIHFDRLVRRASDGVVKEVVLATNFTNEGEATAHYLGQTLKARGLAVTRLARGVPVGGELEYVDAGTIARAMLDRRTM
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: MDM12_ASPOR
Sequence: MSIEVDWRAATSGPDGEALAERIRSFIHDKFQQVALPRFIRSVQVHSFDFGTIPPDLEVKDICEPFADFYEEDEDDETSDVSEELVSGHGTQWHRDLNEPPFHEEMAMNRPLRDPFDEAFHSSTLRSPMEHLNPHFLPRAGTPGIPGGTSTLGYHLMSLGGLSGTQTPLAAVAGGTPFANGWTDPGMGASSRGHPSISGPTAVHPSRMEADIDTSNPTSRPSTSSTLPSHPSASNQPSGDATTGKEHGSLAEDEHLDDPMTSGHPLRLPPRMRERRPEDFQVLCHAKYAGDVRLSLTAEILLDYPMPSFVGLPLKLNVTGITFDGVAVIAYIRKRVHFCFLSAEDADALIGSDQQEARGQDDRPWSSADPTASPKRQGGLLREIRVESEIGRKEDGKQVLKNVGKVERFVLAQVRRTFEEEMVFPSFWTFLI
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  Mdm12 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10.  The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The mdm10-mdm12-mmm1 subcomplex further acts in the TOM40-specific pathway after the action of the mdm12-mmm1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 12, Mitochondrial inheritance component MDM12.
What is the protein family that this protein belongs to?
Belongs to the MDM12 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: GLGA_SALCH
Sequence: MQVLHVCSEMFPLLKTGGLADVIGALPAAQIADGVDVRVLLPGFPDIRRGIPDAHVVSRRDTFAGKISLLFGHYNGVGIYLIDAPHLYERPGSPYHDTNLYAYTDNVLRFALLGWVGCEMACGLDPFWRPDVVHAHDWHAGLAPAYLAARGRPAKSVFTVHNLAYQGMFYAKHMDDIELPWSFFNMHGLEFNGQLSFLKAGLYYADHITAVSPTYAREITEPQFAYGMEGLLRQRHLEGRLSGILNGVDEKIWNPESDLLLASRYKRDTLEEKAENKRQLQIAMGLKVNDKVPLFAVVSRLTNQKGLDLVLEALPGLLEQGGQLALLGAGDPVLQEGFLAAAAEHPGQVGVQIGYHEAFSHRIMGGADVILVPSRFEPCGLTQLYGLKYGTLPLVRRTGGLADTVSDSSLENLADGIASGFVFEDSNAWSLLRAIRRAFVLWSRPSLWRFVQRQAMAMDFSWQVAAKSYRELYYRLK
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: RPOB_BRUME
Sequence: MAQTHSFNGRKRVRKFFGKIPEVAEMPNLIEVQKASYDQFLMVEEPSGGRPDEGLQAVFKSVFPIQDFSGASMLEFVRYEFDPPKFDVDECRQRDLTYSAPLKVTLRLIVFDIDEDTGAKSIKDIKEQDVYMGDMPLMTDNGTFIVNGTERVIVSQMHRSPGVFFDHDKGKTHSSGKLLFAARVIPYRGSWLDIEFDSKDIVYARIDRRRKLPATTLLMALGMDGEEILSTFYKTVTYTRDGDNWRIPYSAERFKGMKIISDLVDADTGEVVLEAGKKLTARAAKQLAEKGLKAIKATEDDLFGSYLAEDVVNYATGEIYLEAGDEIDEKVLKTLIDTGETEINVLDIDHVNIGAYIRNTLAVDKNESRQEALFDIYRVMRPGEPPTMDSAEAMFHSLFFDSERYDLSAVGRVKMNMRLDLDAEDTVRVLRKEDILAVVKMLVELRDGRGEIDDIDNLGNRRVRSVGELMENQYRVGLLRMERAIKERMSSIEIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEITHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATFARVNKYGFIESPYRKVVDGKVTNDVVYLSAMEEAKHSVAQANVELDEQGGFVDEFVICRHAGEVMMAPRENVDLMDVSPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLVRAEAPFVGTGMEPIVARDSGAAIAARRGGIVDQVDATRIVIRATEELDPSKSGVDIYRLQKFQRSNQSTCINQRPLVRVGDRIHKGDIIADGPSTDLGDLALGRNVLVAFMPWNGYNYEDSILLSEKIVSDDVFTSIHIEEFEVAARDTKLGPEEITRDIPNVSEEALKNLDEAGIVYIGAEVHPGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSMRMPPGTYGTVVEVRVFNRHGVEKDERAMAIEREEIERLAKDRDDEQAILDRNVYGRLADMIDGKVAAAGPKGFKKGTTITRELMTEYPRSQWWQFAVEDEKLQGELEALRSQYDDSKKLLEARFMDKVEKVQRGDEMPPGVMKMVKVFVAVKRKIQPGDKMAGRHGNKGVVSRILPVEDMPFLEDGTHADIVLNPLGVPSRMNVGQILETHLGWACAGMGKKIGELLDVYRKTANIEPLRQTLEHIYPDNDRNEPVRSYDDDAILMLANQVKRGVSIATPVFDGAVEADINAMLTDAGLATSGQSTLYDGRTGEPFDRQVTMGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYEAIVRGDDTFEAGIPESFNVLVKEMRSLGLNVELDDTREAEQPALPDAAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: MNMA_LACAC
Sequence: MVDNSKIRVVVGMSGGVDSSVSALLLKQQGYDVVGVFMKNWDDTDDSGVCTATEDYEDVKKVADKIGIPYYSINFEKEYWHRVFEYFLDEYKKGRTPNPDVMCNSQIKFKSFLEFAMDLDADYIAMGHYAKTITDANGVTHMMRPKDGNKDQTYFLSQLSQDQIKKVIFPLANLTKPQVREIALANGLVTAKKKDSTGICFIGERNFRKFLSEFLPAKSGKMVTPEGKVVGEHAGLMYYTIGQRQGLGLGSTKESTDPWFVVGKDLKKNELIVEQGYDSPLLYASRLKASDMSFFTGKPDHDFEMHCTAKFRYRQCDIGVTVKYHADDNTVDVYFDEPARAVTPGQALVLYNGEECIGGGNIDAAFQEDKQLQLV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_GEOUR
Sequence: MREKLEALLADAVAELSQVSTEDGLQELRVKYLGKKGELTAVMKGLGALSPEERPVIGQVVNTVKGELEAKIESAGLKIREDIKAEKLRSERVDVTLPGRRRPIGTRHPITLVIEEITAIFAGLGFLVAEGPEIEHDFYNFEALNFPKDHPARDMQDTFFISDTVLLRTHTSPVQIRTMLKQAPPVRIIAPGTVYRCDSDATHSPMFHQIEGLMVDKGVTFGDLKGILTIFINQLFGQGTGVRLRPSFFPFTEPSAEVDIACVICKGKGCRVCKNTGWLEILGAGMVDPEVYRHVNYDSEIYSGFAFGMGIERIAMLKYGISDMRLLFENDLRFLKQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOT13_BOVIN
Sequence: MAYRAEPPDGGWGWMVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEPAARVSWIASIGIAVQQFGSPVGSALSTKFGPRPAVMTGGILTALGMLLASFATSLTHLYLSIGLLSGSGWALTFTPTLACLSRYFSRRRSLAMGLALTGVGLSSFAFAPLFQWLLNHYAWRGALLLVSALSLHLVACGALLRPLSLAEDPVVGGPGAQITSLLRHGPFLRYTVALTLINTGYFIPYVHLVAHLRDLGWDPLPAAFLLSVAAISDLVGRVASGWLGDAVPGPVARLLMLWTTLTGVILALYPVAEAPTGLVALTMAYGFTSGALTPVAFSVLPELVGTGKIYCGLGLVQMVESIGGLLGAPLSGYLRDVTGNYTASFVVAGAFLLAGSGVLITLPHFFCFSAPTSKPQDLVTEALDTKVPLPEEGLGED
What is the function of this protein?
Proton-linked monocarboxylate transporter.  May catalyze the transport of monocarboxylates across the plasma membrane.
What are the official names of this protein?
Monocarboxylate transporter 13, MCT 13, Solute carrier family 16 member 13.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: GTPB8_HUMAN
Sequence: MAAPGLRLGAGRLFEMPAVLERLSRYNSTSQAFAEVLRLPKQQLRKLLYPLQEVERFLAPYGRQDLHLRIFDPSPEDIARADNIFTATERNRIDYVSSAVRIDHAPDLPRPEVCFIGRSNVGKSSLIKALFSLAPEVEVRVSKKPGHTKKMNFFKVGKHFTVVDMPGYGFRAPEDFVDMVETYLKERRNLKRTFLLVDSVVGIQKTDNIAIEMCEEFALPYVIVLTKIDKSSKGHLLKQVLQIQKFVNMKTQGCFPQLFPVSAVTFSGIHLLRCFIASVTGSLD
What are the official names of this protein?
GTP-binding protein 8.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: NU4LC_ATRBE
Sequence: MILEHVLVLSAYLFSIGIYGLITSRNMVRALMCLELILNAVNINFVTFSDFFDNRQLKGDIFSIFVIAIAAAEAAIGLAIVSSIYRNRKSTRINQSNLLNN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SCPA_THEP3
Sequence: MYNVKLEVFEGPFDLLFHLIEKNEIDLMDIPISVILDQYMEYIKTLQEMDLNVASEFIVMAATLLEIKSKMLLPKQKFEGQQLEMEEVDPREELVTKLIEYKKYKIIAQTFKEMCKIGSRFFREEPEVKYIDKKIAFNYSSEDIYKAYLKVISKNNAKEDEIEIKKDEYTVESKIKELLVKLVKKTVLWFSEFIKKSRAKGEIIVSFIAVLELVRLNKIIAEQKTTYGDILIKSFGRGEKNEQ
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: RL4_LEUCK
Sequence: MTKVAVLKQDGSQAAELELNDAVFAIEPNNAVITDAVLMQRASMRQGTHAVKNRSAVSGGGRKPWKQKGTGRARAGSIREPQFRGGGIVFGPTPRSYAYRINRKAYQLALKSVLSQKVAEGKLVVVDALSFEAPKTQDFKKVLANLSVDTKTLVVVDEDNENAILSARNLTNVQVMTTKGINVLDVVNADKLVIVQSSIEEIQGGLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: ASSY_BURMA
Sequence: MTTILENLPAGQKVGIAFSGGLDTSAALHWMRIKGAVPYAYTANLGQPDEDDYDAIPKRAIQYGAEGARLIDCRAQLVAEGIAALQCGAFHISTAGVTYFNTTPIGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLVNPDLKIYKPWLDQQFIDELGGRAEMSEFMRQAGFEYKMSAEKAYSTDSNLLGATHEAKDLESLESGIKIVNPIMGVAFWRDDVKIDKEEVTIRFEEGRPVALNGVEYKDAVALLLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGLALLYIAYERLVTGIHNEDTIEQYRENGRRLGRLLYQGRWFDPQAIMLRETAQRWVARAVTGEVTVELRRGNDYSIIGTRSPNLTYQPERLSMEKVQSMFSPRDRIGQLTMRNLDITDTRDKLRIYSQVGLLAAGESSALPKLKEDESGN
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FSA_STRPN
Sequence: MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERIKDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALKKEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNSPSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQNSRSI
What is the function of this protein?
Catalyzes the reversible formation of fructose 6-phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction.
What are the official names of this protein?
Probable fructose-6-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAC_LACLS
Sequence: MNNLNSVFDYEDIQLIPNKCVINSRSEADTSVKLGNYTFKLPVVPANMQTIIDDKIAEMLAKEGYFYIMHRFEAENRAAFIKKMHKDGLIASISVGVKADEHAFIREISAEALIPEFITIDIAHGHADSVIKTIQLIKRLMPQTFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITKVKTGFGTGGWQLAAVKWCAKAASKPVIADGGIRTHGDIAKSIRMGATMVMVGSLFAAHEESPGQTVERDGQLFKEYFGSASEYQKGEHKNVEGKKILLPHKGSLKDTLKEMEEDLQSSISYAGGRDLSALTKVDYVVVKNSIWNGDAI
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: DCE_YEAST
Sequence: MLHRHGSKQKNFENIAGKVVHDLAGLQLLSNDVQKSAVQSGHQGSNNMRDTSSQGMANKYSVPKKGLPADLSYQLIHNELTLDGNPHLNLASFVNTFTTDQARKLIDENLTKNLADNDEYPQLIELTQRCISMLAQLWHANPDEEPIGCATTGSSEAIMLGGLAMKKRWEHRMKNAGKDASKPNIIMSSACQVALEKFTRYFEVECRLVPVSHRSHHMLDPESLWDYVDENTIGCFVILGTTYTGHLENVEKVADVLSQIEAKHPDWSNTDIPIHADGASGGFIIPFGFEKEHMKAYGMERWGFNHPRVVSMNTSGHKFGLTTPGLGWVLWRDESLLADELRFKLKYLGGVEETFGLNFSRPGFQVVHQYFNFVSLGHSGYRTQFQNSLFVARAFSFELLNSSKLPGCFEIVSSIHESIENDSAPKSVKDYWEHPQAYKPGVPLVAFKLSKKFHEEYPEVPQAILSSLLRGRGWIIPNYPLPKATDGSDEKEVLRVVFRSEMKLDLAQLLIVDIESILTKLIHSYEKVCHHIELASEQTPERKSSFIYEMLLALASPQDDIPTPDEIEKKNKLKETTTRNYRGTC
What are the official names of this protein?
Glutamate decarboxylase, GAD.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: THID_MYCTU
Sequence: MNYLPLAPPGMTPPRVLSIAGSDSGGGAGIQADMRTMALLGVHACVAVTAVTVQNTLGVKDIHEVPNDVVAGQIEAVVTDIGVQAAKTGMLASSRIVATVAATWRRLELSVPLVVDPVCASMHGDPLLAPSALDSLRGQLFPLATLLTPNLDEARLLVDIEVVDAESQRAAAKALHALGPQWVLVKGGHLRSSDGSCDLLYDGVSCYQFDAQRLPTGDDHGGGDTLATAIAAALAHGFTVPDAVDFGKRWVTECLRAAYPLGRGHGPVSPLFRLS
What is the function of this protein?
Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.
What are the official names of this protein?
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase, Hydroxymethylpyrimidine kinase, HMP kinase, Hydroxymethylpyrimidine phosphate kinase, HMP-P kinase, HMP-phosphate kinase, HMPP kinase.
What is the protein family that this protein belongs to?
Belongs to the ThiD family.
Protein: NTNF_NECSZ
Sequence: MAAAGARHYTSKDGSQHDLVRGIWKLLRLHTPEGLSTASIGWLALFFYAIQQQLSFESLRYTFLGIFACYQITHGVFCMWNDICDRDFDAQVARTKKRPLPSGMVTYTEAMVAFIIGLALSLGVTYAMLGEDVTLTMGPIWGLSFIYPLCKRAIWAPQAVLGLTMAACVLPPWVALGNDATNAKLPASLFGAIFSWLVYLDLIYASQDRPDDEKAGVKSLAVFLGDKLKACLTVLGALQIAFFAVAAFEASASSFLWVFGIAVWAISVPWSILSLNPRDRNSGGRIFLVNAILGIYLAAVSGTDVWLSSR
What is the function of this protein?
olyprenyl transferase; part of the gene cluster that mediates the biosynthesis of the meroterpenoids nectripenoids A and B, as well as cochliquninone D and isocochliquninone E (PubMed:29797385).  The pathway probably begins with the HR-PKS ntnH that catalyzes two chain-extension steps to form a reduced triketide, which then primes the SAT domain in the NR-PKS ntnG to initiate three more cycles of extension to give a linear hexaketide corresponding to the polyketide part of nectripenoids (Probable).  The FAD-dependent monooxygenase ntnJ then performs an oxidative decarboxylation at C11 of the ntnH/ntnG product, via an electrophilic aromatic hydroxylation with concomitant ipso-decarboxylation (Probable).  The membrane-bound polyprenyl transferase ntnF then introduces a farnesyl group before the FAD-dependent monooxygenase ntnK functions as the first epoxidase on terminal C12'-C13' olefin, followed by a second epoxidation on C7'-C8' catalyzed by ntnA (Probable).  The terpene cyclase/mutase ntnI then initiates the sequential tricyclic ring formation through protonation of the terminal epoxide and catalyzes the regioselective and stereoselective 6/6/6-tricyclic ring formation (Probable).  The cytochrome P450 monooxygenase ntnM may then hydroxylate C1' (Probable).
What are the official names of this protein?
Polyprenyl transferase ntnF, Nectripenoid biosynthesis cluster protein F.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MRFL_BOVIN
Sequence: MDVVGENEALQQFFEAQGANGTLGNPTLDTSLLEEFLGNDFDLGALQGQLPDTPPYSASDSCSPPQVKGACCPTLTPAARGTPAALLHSANAPGILPAHQSHSSSEMSNSGLPHRTFHNCYPDASHLMSPLDQSVSGGIGCSYHQQPLCHSPGVSLPPTKKRKCTQVLEDSGDCHVWTHHSRPMTGRSHSIEVQDLDSERQNMMLADQPSPALKWQPYRSVPWHSLLNSQYEKLPDVGYRVVTDKGFNFSPADEAFVCQKKNHFQITIHIQVWGSPKFVKTQMGLKPIEMFYLKPFGVKVEATNQIIAIEQSQADRSKKIFNPIKINLLADQVTKVTLGRLHFSETTANNMRKKGKPNPDQRYFMLVVGLYAANQDQFYLLSAHISERIIVRASNPGQFENDIDALWQRGQVPESVVCHGRVGINTDAPDEALVVCGNMKVMGTIMHPSDSRAKQNVQEVDTNEQLRRIAQMRIVEYDYKPEFASAMGINTAHQTGMIAQEVREILPRAVREVGDVTCENGETLENFLMVDKDQIFMENVGAVKQLCKLTNNLEERIEELEIWNRKLARLKRLSSSKSSASEASSISKFSRALSASSPKRTISKKNSKVSFSGKKQSCPNWVFQSLVITLIAVMAFCLKDQDRCTPSAPSSNLTSSQEPALPSTASPSAPNTTLATTLPSFQVPEITFCEILPCQQTYCCPIWGTRRGLSSPMQRQLEEQEPHQGPWAGRSTSFLAAEAQTNVDWRSDWIDTTISSIQIMEIQQIIDRRYCSRSLQCGSGNYYYHIPVNKYTPTNVKFSLEINTTEPLIVFQCKFTLGNMCFRSKIEAKGMESQQEVSQEMTQGYQHIWSLPVAPLFDSGYHFRVAAPDLADCSTDPYFAGKFFTDYFFYFYRHCV
What are the official names of this protein?
Myelin regulatory factor-like protein.
What is the protein family that this protein belongs to?
Belongs to the MRF family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CP2CQ_MESAU
Sequence: MDAFVVLVFILSCLFLLSLWRQSSERGKLPPGPTPLPIIGNFLQIDVKDISGSLTNFSKVYGPVFTLYLGMKPTVVLHGYEAVKEALIDHGEEFAGRGSFPVAERVNKGLGIVFSNGSRWKETRRFSLMTLRNLGMGKRSIEDRVQEEAQCLVEELRKTNGSPCDPTFILGCAPCNVICSIIFQNRFDYKDKDFLTFMKKLNENARILSSPWFQVCNNFPLLIDYCPGSHHRITKNINYIRSYLSEKMKEHQESLDVANPRDFIDYYLIKLKQGNYNQQSEFSPENLATTVSDLFAAGTETTSTTLRYALLLLLKHPHVTAKVQEEIDQVVGRHRNPCMQDRSHMPYTDAMIHEVQRFIDLIPTNLPHAVTCDIKFRDYFIPKGTTIITSLSSVLHDSKEFPNPEVFDPGHFLDKNGNFKKSDYFMPFSTGKRMCAGEGLARMELFLFLTTILQNFKLKSLVHPKDIDTTPVLNGFASLPPSYQLCFIPV
What is the function of this protein?
Catalyzes the hydroxylation of tolbutamide and the N-demethylation of aminopyrine and benzphetamine.
What are the official names of this protein?
Cytochrome P450 2C26, CYPIIC26, Cytochrome P450 HSM2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: RISB_SULTO
Sequence: MPDQSINLAIVVAEFNYDITYLMLQRAIAHAKFLGANVKVVFKVPGSYDMAIAVKELLKRDDIDAVVTLGAVIKGETKHDEIVATQTARKILDLSVEYGKPVTLGIIGHGVTHEQAVERIEEYSTRAVEAAIKLAKRLRELRKIQTLNEEMVVIE
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RSSA2_ARATH
Sequence: MAANGVATAGRQVSEKEADIQMMLSADVHLGTKNCNYQMERYVFKRRDDGIYIINLGKTWDKLQMAARVIVAIENPKDIIVQSARPYGQRAVLKFAQYTGVNAIAGRHTPGTFTNQMQTSFSEPRLLILTDPRTDHQPIKEGALGNIPTIAFCDTDSPMGFVDIGIPANNKGKHSIGCLFWLLARMVLQMRGTILAAQKWDVMVDLFFYREPEEAKQEGDEEAEVQADYGMVGGDQWTTAQISDAAWSGEVEQPISAAPAVGVTVAAGWEAASVPAAGWE
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein Sa-2, p40 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNC5C_CHICK
Sequence: MGKGLEGTAARCGLGMGYLLHSVVLPALAVLGASRPGSAAQDDDFFHELPETFPSDPPEPLPHFLIEPEEAYIVKNKPVNLYCKASPATQIYFKCNSEWVHQKDHVVDERVDETSGLIVCEVSIEISRQQVEELFGPEDYWCQCVAWSSAGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEEVIDPVEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWSACNSRCGRGFQKRTRTCTNPAPLNGGAFCEGQNVQKIACTTLCPVDGKWTSWSKWSTCGTECTHWRRRECTAPAPKNGGKDCEGLVLQSKNCTDGLCMQAAPDSDDVALYVGIVIAVIVCLAISVVVALFVYRKNHRDFESDIIDSSALNGGFQPVNIKAARQDLLAVPPDLTSAAAMYRGPVYALHDVSDKIPMTNSPILDPLPNLKIKVYNTSGAVTPQDELSDFSSKLSPQITQSLLENETLNVKNQSLARQTDPSCTAFGTFNSLGGHLVIPNSGVSLLIPAGAVPQGRVYEMYVTVHRKEGMRPPVEDSQTLLTPVVSCGPPGALLTRPVVLTMHHCAEPNMDDWQIQLKHQAGQGPWEDVVVVGEENFTTPCYIQLDPEACHILTETLSTYALVGQSITKAAAKRLKLAIFGPLSCSSLEYSIRVYCLDDTQDALKEVLQLERQMGGQLLEEPKTLHFKGSTHNLRLSIHDIAHSLWKSKLPAKYQEIPFYHIWSGCQRNLHCTFTLERFSLNTLELVCKLCVRQVEGEGQIFQLNCSVSEEPTGIDYPIMDSAGSITTIVGPNAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLKLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAEGNY
What is the function of this protein?
Receptor for netrin required for axon guidance (By similarity).  Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding (By similarity).  Involved in dorsal root ganglion axon projection towards the spinal cord (PubMed:28483977).
What are the official names of this protein?
Netrin receptor UNC5C, Protein unc-5 homolog 3, cUNC-5H3, Protein unc-5 homolog C.
What is the protein family that this protein belongs to?
Belongs to the unc-5 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell surface. Synapse, synaptosome. Cell projection, axon. Cell projection, dendrite. Cell projection, growth cone. Cell projection, lamellipodium. Cell projection, filopodium.