PharMolix/UniProtQA huggingface dataset:
Protein: FOLD_BACCQ
Sequence: MVAVIIKGNEVAEKKRAQLTEEVVKLKEQGIVPGLAVILVGEDPASRSYVKGKEKGCEQVGIYSELIEFPETITEERLLAEIDRLNGDDRINGILVQLPLPKHIEEKAIIERISPEKDVDGFHPISVGRMMTGQDTFLPCTPHGIVELVKETNLDISGKHVVVIGRSNIVGKPVGQLFLNENATVTYCHSKTQNMKELTKLADILIVAVGRPKMVTADYIKEGAVVIDVGVNRLETGKLCGDVDFDNVLDVAGYITPVPKGVGPMTITMLLHNTVESAKRAGVVCK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RLA2_LEIBR
Sequence: MQYLAAYALVALSGKTPCKADVQAVLKAAGVAIELSRVDALFQELEGKSFDELMTEGRSKLVGSGSAAPAAAASTAGAAVAAAADAKKEASEEEADDDMGFGLFD
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P2, Acidic ribosomal P2 beta protein, P2B-protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: SYE_BURL3
Sequence: MTRPVRTRFAPSPTGFIHLGNIRSALYPWAFARKMKGTFVLRIEDTDVERSSQEAVDAILDGMQWLGLDFDEGPIYQMQRMDRYREVIAQMLEKGLAYPCYMSAEELDALRERQREAGLKPRYDGTWRPEPGKVLPEPPAGVKPVLRFRNPLTGTVVWDDAVKGRVEISNEELDDLVIARPDGTPIYNFCVVVDDMDMGITHVIRGDDHVNNTPRQINILNALGGEPPVYAHLPTVLNEQGEKMSKRHGAMSVMAYRDAGFLPEAVVNYLARLGWSHGDAEIFSREQFVEWFDLEHLGKSPAQYDHSKLSWLNAHYIKEADNARLAELAKPFLAALGIDDAAIATGPALEAVVGLMKDRATTVKEIAEGATMFYRVPAPEADALAQHVTDVVRPALADLVAALKAADWTKEAVSAALKATLGTHKLKMPQLAMPVRLLVAGTTHTPSIDAVLVLFGRDVVVSRIEAALA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGB_PROM9
Sequence: MIETIQADWIQSEAINLENCCNDNPLKILGPHFYEEQWVIRVWMPEADEVKINFKNNTYKAESINHKWLFEAILPENPESNYEINISRGGITHTQHDPWSYIEEWMGEVDRHLFAEGNHHHIWEKMGAHLIEEKNQKGVMFCIWAPNAKSISIIGDINSWDGRHHPMQKRLGGIWELFMPTMEEGDTYKYEIRTQQGHIYEKADPYGFLHEIRPQNGSIVSKLKNFNWNDNAWITNRDSSSQINKPISVYEMHLGSWLHESTDNKYIEDNGNPRNPVPAADLKPGTRLLTYPELTEKLIPYVKDRGFTHIELMPISEHPFDGSWGYQVTGWYAPTSRFGTPNEFREFVNKCHEEGIGVILDWVPGHFPKDKHGLAFFDGCHLYEHGDSRIGEHKEWGTLIFNYSRNEVRNFLVANLVYWFEEFHIDGIRVDAVASMLYRDYLRPDGEWIPNENGGNENIEAVKFLQQANHVLFQHFPGALSIAEESTTWPMVTKPTDMGGLGFNLKWNMGWMHDMLDYFEIDPWFRQFHQNSVTFSITYNYTENFMLALSHDEVVHGKSHLLHKMPGDDWKKYANTRALLTYMWTHPGKKTIFMGMEFGQRQEWNVWDDLQWDLLEFEPHKGIRNLVDDLNALYKNEPALWKNDFDPYGFQWIDCNDKSNSVISFMRRENDTNEWLVIVANFTPNTHDSYKVGVPVEGFYKEIFNSDGSRYGGSNKGNMGGKEAINYNIHDYQNALELALPPLSVSIFKHQSKK
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: BSHC_BACMK
Sequence: MEIKEISVPLQGVVADYMNGKKEIQSCFDYLLTEDAFKQRLHDLREREFFRQDLVTHLLEYNTQLQAGEFTIQNIKALEDENTYVVIAGQQAGLLTGPLYTVHKIISILQLAKEKEESLGVRVVPVFWIAGEDHDMDEINHTFVTKNKKIKKTIFHDRYPKKASASESEFSIEDCRKWVEEIFKTYPETNFTKDVLQFVDDALGKSHTYVDFFAHLITKMFANSGLILVDSHHPALRKLEVPFLQQIISKYKEIQVGLRNQQEVLKELGFKPIIETKTNAVHIFMEIDNERVLLEENQGKFIGKDGVHSFSYEELMEEMERSPERFSNNVVTRPLMQEYVFPTLAFIGGPGELAYWSELQQVFHTAGFQMPPVVPRLTITYMERDTATDLYDLDLQEIDPFLNNIDNLRDNWLSNQIEEPIDERFIEAKKEIMDIHTSLQQFVKKIDPGLNEFAGKNELKINEQIELLEKMLKRNVEKKHEVQLNKFRRLQFALRPLGAPQERVWNVCYYLNQFGLDFVDRVMEQSFSWDGKHHVIKL
What is the function of this protein?
Involved in bacillithiol (BSH) biosynthesis.  May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.
What are the official names of this protein?
Putative cysteine ligase BshC.
What is the protein family that this protein belongs to?
Belongs to the BshC family.
Protein: 3DHQ1_NEOFI
Sequence: MGKSILLINGPNLNLLGTREPQIYGSTTLADVEASCKAHAESLGATLATFQSNHEGAIIDRIQAARGNVDGIVINPGAFTHTSVAIRDALLGVGIPFIELHVSNVHAREPWRHHSYFSDKAAGIIVGLGVYGYKVAVEHVALNFKERAIL
What is the function of this protein?
Is involved in the catabolism of quinate.  Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway.
What are the official names of this protein?
Catabolic 3-dehydroquinase 1, cDHQase 1, 3-dehydroquinate dehydratase 1.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: MIAB_ALKOO
Sequence: MSKRAKVVVSPEKIKKQSDIIEELKIYNRGKNKKYMITTYGCQMNEHDSETLSGMLENMGYSITTNKEEANLIIYNTCCVRENAELKVYGNIGALKALKKKNEDLIIAVCGCMMQQPQVVKEIKRKYRHVDLVFGTHNLYRFPELLSRSMETEGMFIEVWDEETGIVEGLPANRKYDLKGFINIMYGCNNFCTYCIVPYTRGRERSREVADIIREATDLANNGTKEITLLGQNVNSYGKTLEHPIDFADLLRALNKIDGIERIRFMTSHPKDLSERLIDAIAECDKVCEHFHLPFQSGSNQILKAMNRKYTKENYLSIVKKLKDRIPNIGLTTDIIVGFPGETEEDFQDTLDIVQEARYDSAYTFLYSIREGTPAAKMQNQIDEKVKQERFSRLLDKVNEISAEINQSYLNKVVEVLVEGPSKTDSNKLMGRTRQNKLVNFSGDESLIGKLVNVRIVECRTFSLNGEVIQE
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_PHEZH
Sequence: MPKLKTKSGVKKRFKMTATGKLKAGVAGKRHRLISHNGKYIRQNRGTKVMSEADAKIIKSWLPYGL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: SODM1_STAAN
Sequence: MAFELPKLPYAFDALEPHFDKETMEIHHDRHHNTYVTKLNAAVEGTDLESKSIEEIVANLDSVPANIQTAVRNNGGGHLNHSLFWELLSPNSEEKGTVVEKIKEQWGSLEEFKKEFADKAAARFGSGWAWLVVNNGQLEIVTTPNQDNPLTEGKTPILGLDVWEHAYYLKYQNKRPDYIGAFWNVVNWEKVDELYNATK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.  Catalyzes the dismutation of superoxide anion radicals into O2 and H2O2 by successive reduction and oxidation of the transition metal ion at the active site.
What are the official names of this protein?
Superoxide dismutase [Mn/Fe] 1.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: SSRP_PSEAE
Sequence: MAKQKKHPSGTIAQNKKALHDYFIEQRFEAGVALAGWEVKSLRAGKAQLVDSYVLLKDGEAWLLGSHITPLTTASTHVIADPVRTRKLLLHKRELGKLFGAVQQKGYACVALSMYWKKHLVKCEIALAKGKKDFDKRHTEKERDSDREIQRAMRHGKDD
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: ZAPA_BACC1
Sequence: MSQQKGKKSRINVEIYGQQYSVVGDESTSHIRMVAAIVDDKMRELNAKNPSLDTSRLAVLTAVNVIHDYIKLKEEHEKLKESMTKKGME
What is the function of this protein?
Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring.  It is recruited early at mid-cell but it is not essential for cell division.
What are the official names of this protein?
Cell division protein ZapA, Z ring-associated protein ZapA.
What is the protein family that this protein belongs to?
Belongs to the ZapA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at mid-cell. In sporulating cells, localizes near the cell poles.
Protein: PEPB_ESCF3
Sequence: MTEAMKITLSTQPADARWGEKATYSINNDGITLHLNGADDLGLIQRAARKIDGLGIKHVQLSGEGWDADRCWAFWQGYKAPKGTRKVEWPDLDDAQRQELDNRLMIIDWVRDTINAPAEELGPSQLAQRAVDLISNVAGDRVTYRITKGEDLRDQGYMGLHTVGRGSERSPVLLALDYNPTGDKEAPVYACLVGKGITFDSGGYSIKQTAFMDSMKSDMGGAATVTGALAFAITRGLNKRVKLFLCCADNLISGNAFKLGDIITYRNGKKVEVMNTDAEGRLVLADGLIDASAQKPELIIDAATLTGAAKTALGNDYHALFSFDDALAGRLLESAAQENEPFWRLPLAEFHRSQLPSNFAELNNTGSAAYPAGASTAAGFLSHFVENYKQGWLHIDCSATYRKAPVEQWSAGATGLGVRTIANLLTA
What is the function of this protein?
Probably plays an important role in intracellular peptide degradation.
What are the official names of this protein?
Peptidase B, Aminopeptidase B.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_STRT2
Sequence: MLYPTPIAKLIDSFSKLPGIGAKTATRLAFYTISMSDEDVNDFAKNLLAAKRELTYCSVCGRLTDDDPCIICTDETRDRTKILVVEDSKDVSAMEKIQEYRGLYHVLQGLISPMNGVGPDDINLKSLITRLMDSEVDEVIIATNATADGEATSMYISRVLKPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: ARLY_STRU0
Sequence: MMGNQKLWGGRFEKGLEQWVEEFGASISFDYKLATFDIKASIAHVSMLGQQGIISKDEAELIKTGLEDIHRDILEEEIVFDSQDEDIHMTIERQLLAKIGPLAGKLHTARSRNDQVATDMHLYLKHILEALLEKLLQLRKVLVTLAEEHIETILPGYTHLQHAQPISFGHHLMAYYQMFTRDSERFKFNMKHTDMSPLGAAALAGTTFPIDRELTAQLLGFNELYHNSLDAVSDRDFIIEFLANASLLMMHMSRFCEEIILWTSYEYQFVSLSDSFSTGSSIMPQKKNPDMAELIRGKTGRVYGNLFSLLTVMKALPLAYNKDLQEDKEGLFDTAETILVAVDILAGMLSTMTVHKETMYRATQKDFSNATELADYLANKDMPFRQAHEIVGQLVLQASKEGIYLQDIPIKDFKAISPLIEEDIYDTLTSRAAVERRTSIGGTGFNQVSSQIALARKDLS
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_BURM7
Sequence: MARGKFITFEGIDGAGKTTHLQWFCDRLQERLGPTGRHVVVTREPGGTQLGETLREILLNQPMDLETEALLMFAGRREHLALVIEPALARGDWVVSDRFTDATFAYQGGGRGLPRDKLEALERWVQGGFQPDLTVLFDVQPQVASARRGAVRMPDKFESESDAFFARTRAEYLRRAHEAPHRFAIVDSSESIPQIRKQLEGVLAAL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: NU4M_BRACM
Sequence: MLEHFCECYSNLSGLILCPVLGSITPLFIPNSRIRPIRLIGLCASLITFLYSPVPRIQFDSSTAKSQFVESLRWLPYENINFYLGIDGISLFFVILTTFLIPICISVGWSGMRSYGKEYITAFLIREFLMIAVFRMLDLLLFYVFPESVPIPMFIIIGVWGSRQRKIKAAYQFFLYTLLGSLFMLLAILLILFQTGTTDLQISLTTEFSERRQIFLWIASFASFAVKVPMVPVHIWLPEAHVEAPTAGSVILAGIPLKFGTHGFLRFSIPMFPEATLCSTPFIYTLSAIAIIYTSLTTSRQIDLKKIIAYSSVAHMNLVTIGMFSPNIQGIGGSILPMLSHGLVPSALFLCVGVLYDRHKTRLVRYYGGLVSTMPNLSTIFFSFTLANMSSPGTSSFIGEFPILVGAFQRNSLVATLAALGMILGAAYSLWLYNRVVSGNLKPDFLHKFSDSNGREVSIFIPFLVGLVRMGVHPKVFPDCMHTSVSNLVQHGKFH
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: ETHE1_MOUSE
Sequence: MASAVVRVAGRRLSQQSASGAPVLLRQMFEPKSCTYTYLLGDRESREAVLIDPVLETAHRDAQLIKELGLKLLYAVNTHCHADHITGTGVLRSLLPGCQSVISRLSGAQADLHIGEGDSIRFGRFALETRASPGHTPGCVTFVLNDQSMAFTGDALLIRGCGRTDFQQGCAKTLYHSVHEKIFTLPGNCLIYPAHDYHGLTVSTVEEERTLNPRLTLSCEEFIKVMDNLNLPKPQQIDIAVPANMRCGVQTPPS
What is the function of this protein?
First described as a protein that can shuttle between the nucleus and the cytoplasm and suppress p53-induced apoptosis by sequestering the transcription factor RELA/NFKB3 in the cytoplasm and preventing its accumulation in the nucleus (By similarity).  Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix.  Hydrogen sulfide (H(2)S) is first oxidized by SQRDL, giving rise to cysteine persulfide residues.  ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide, once it has been transferred to a thiophilic acceptor, such as glutathione (R-SSH).  Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H(2)S levels that have toxic effects, due to the inhibition of cytochrome c oxidase.
What are the official names of this protein?
Persulfide dioxygenase ETHE1, mitochondrial, Ethylmalonic encephalopathy protein 1 homolog, Hepatoma subtracted clone one protein, Sulfur dioxygenase ETHE1.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion matrix.
Protein: RS2_SYNPW
Sequence: MAVVTLAEMMEAGAHFGHQTRRWNPKMSRYIYCARNGVHIIDLVQTAVCMNNAYKWVRSAARSGKRFLFVGTKKQASEVVAQEALRCGGSYVNQRWLGGMLTNWTTMKARIDRLKDLERMEASGAIAMRPKKEGAVLRRELDRLQKYLGGLKNMRRLPDVVVLVDQRRETNAVLEARKLDIPLVSMLDTNCDPDLCEVPIPCNDDAVRSVQLVLSRLADAINEGRHGSNEQRGGDGSEG
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: PUR9_CHESB
Sequence: MTVSAKNIPAPDLVPVRRALISVSDKTGIVDFARSLAAREVALASTGGTAALLARSGIGVMDVSQLTGFPEIMDGRVKTLHPAVHGGLLAIRDDPDHRSAMETHAIKPIDLVVINLYPFEDVRFGGGDYAATVENIDIGGPAMLRAAAKNHAYVAVVTDPADYARVLEALEKNDGALPYRLRQELAAKAYARTAAYDAAISQWFAESLAIAEPEWRSFGGRLAQVMRYGENPHQQAGFYATGEKRPGVATARQVQGKQLSYNNINDTDAAFELVCEFDPKKVAAVAIIKHANPCGVAEGTSLAEAYRKALACDPVSAFGGIVALNRILDAEAAEEIAKIFTEVIIAPDATEEAQAIIATKKNLRLLLTEGVADPRAPGLSAKTVAGGLLVQTRDNGVIDDLDLRVVTRRAPSEKEMANLKFAFRVAKHVKSNAIVYARDLATVGIGAGQMSRVDSARIAARKAEDAAAAAGGQPLTKGSVVASDAFFPFADGLLSAVEAGATAVIQPGGSMRDDEVIKAADEHGIAMVFTGMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: SIN3B_HUMAN
Sequence: MAHAGGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKLPVHVEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNIQSPLTSQENSHNHGDGAEDFKQQVPYKEDKPQVPLESDSVEFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKRSLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSAPAKKKMKLRGTKDLSIAAVGKYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVSPFLGKFPELFAQFKSFLGVKELSFAPPMSDRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTAICKELDHWTLLQGSWTDDYCMSKFKNTCWIPGYSAGVLNDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQRRAIYRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSPQGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNNWYFFLRLHQTLCSRLLKIYRQAQKQLLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPSEVELEEYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHLVSDDVCLKVVELYLNEKKRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQRKGQVIMTIELLDTEEAQTEDPVEVQHLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLKKFRRRWQSEQARALRGEARSSWKRLVGVESACDVDCRFKLSTHKMVFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHQHFEEWHSRWLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCETVHVHGLPVTRYRVQYSRRPASP
What is the function of this protein?
Acts as a transcriptional repressor.  Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities.  Interacts with MAD-MAX heterodimers by binding to MAD.  The heterodimer then represses transcription by tethering SIN3B to DNA.  Also forms a complex with FOXK1 which represses transcription.  With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression.
What are the official names of this protein?
Paired amphipathic helix protein Sin3b, Histone deacetylase complex subunit Sin3b, Transcriptional corepressor Sin3b.
What are the subcellular locations of this protein?
Nucleus.
Protein: MTLD_GEOSE
Sequence: MLAVHFGAGNIGRGFIGSLLSQSGYEVVFVDINDELVRLLKEKQEYRVIIADENRQELLIRNVSAVNSQTEREKVIDYITKAHLITTAVGPHILPAIATILAEGLQKRITINKTPLHIIACENMIGGSDVLKSHVFEKISEADKPLFEKYYGFLNCAVDRIVPNQKHDDPLSVVVEPFFEWVIEKRNIIGAIPPIQGAHFVDDLKPYIERKLFTVNTGHAIASYLGYYKKLQTIQEAMCDQEIRSDVEKALHESGAVLVKKYGWNENEHQSYIQKIIQRFINPSISDEVVRVARSPIRKLGANDRLIGPATQYYDLFGQVPHGLVKGIAALLLFDYENDEEAVALQKTIQETGVEGALYQYSQLEKDHPLVIAIKDQWQHLK
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: RBL_HYDTE
Sequence: MSQPKRYEAGVKEYRETYWEPTYVPKDSDFLAVFKIVPQPGVPREESAAAVAAESSTATWTTVWTDLLTDLYYYKGRAYAIEDVPGDDEAFYAFIAYPMGLFEEGSVVNVFTSLVGNVFGFKAVRSLRLEDVRIPLWFVTTCPGPPHGIYVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCQEAIEKAQAETGERKGHYMNVTGPTMEEIYKRAEFAKEIGTPIIMIDYLTVGWAATQSLSKWCRDNGMLLHVHRAMHAVIDRNPKHGINFRVLAKIMRLIGGDHLHSGTVVGKLEGDRAATLGWIDLMRDRYVKADRSRGIFFDQDWGQMPGMFPVASGGIHVWHMPALVSIFGDDSVLQFGGGTIGHPWGNAAGACANRVALEACVKARNEGLPIEKMGREILTEAAKSCPELKVAMETWKEVKFDFDTVDKLDVQHR
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
Protein: DAPD_ACIET
Sequence: MTQQLQTLIDNAWDNRASLSPSAAPKEVVDAVEHVIAELNNGRLRVATREGVGQWTVHQWIKKAVLLSFRLKDNELMKAGDLGFFDKVPTKFAHLSADEMAATGVRVVPPAVARRGSFIAKGAILMPSYVNIGAYVDEGTMVDTWATVGSCAQVGKNVHLSGGVGLGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEENSVISMGVYIGQSTPIYDRTTGETTYGRVPAGSVVVSGNLPKDGGRYSMYAAIIVKKVDAKTRSTTSLNDLLRD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROB_RIPO1
Sequence: MKQTIVIKIGTSSLTQPESGKLALSTIAALVETLTQLRQLGHRIILVSSGAVGVGCSRLNLKERPKKMAMKQAIAAVGQGRLIRVYDDLFNTLGQPIAQVLLTRRELIERSCYVNASNTFESLLELGVIPIVNENDTVAIEELKFGDNDTLSALVASLIHADWLFLLTDVDRLYSADPRLVPDAKPITLVNSDEFAQLQVKAGDRGSQWGTGGMATKLAAARIATGAGVRTVITHGGKPSNLLKILQGEAIGTQFEPQTRNDSARKRWIAYGLLPTGKLYLDSGAIRAICHQGKSLLAAGIIKVEGQFEASEAVQLCDETGQEMARGIVNYNSLEIDKIKGHHSDEISQILGYGGAETVVHRDNLSVNG
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNMP1_HELVI
Sequence: MQLPKELKYAAIAGGVALFGLIFGWVLFPTILKSQLKKEMALSKKTDVRKMWEKIPFALDFKVYIFNFTNAEEVQKGATPILKEIGPYHFDEWKEKVEVEDHEEDDTITYKKRDVFYFNPEMSGPGLTGEEIVVIPHIFMLGMALTVARDKPAMLNMVGKAMNGIFDDPPDIFLRVKALDILFRGMIINCARTEFAPKATCTALKKEAVSGLVLEPNNQFRFSIFGTRNNTIDPHVITVKRGIKNVMDVGQVVAVDGKLEQTIWRDTCNEYQGTDGTVFPPFVPETERIQSFSTDLCRTFKPWYQKKTSYRGIKTNRYVANIGDFANDPELNCFCPKPDSCPPKGLMDLAPCMKAPMYASMPHFLDSDPELLTKVKGLNPDVTQHGIEIDYEPITGTPMVAKQRIQFNIQLLKTDKLDLFKDLSGDIVPLFWIDEGLALNKTFVNMLKHQLFIPKRVVGVLRWWVVSFGSLGAVIGIVFHFRDHIMRLAVSGDTKVSKVTPEEPEQKDISVIGQAQEPAKVNI
What is the function of this protein?
Plays an olfactory role that is not restricted to pheromone sensitivity.
What are the official names of this protein?
Sensory neuron membrane protein 1, SNMP1-Hvir.
What is the protein family that this protein belongs to?
Belongs to the CD36 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MLTC_ECOLC
Sequence: MKKYLALALIAPLLISCSTTKKGDTYNEAWVKDTNGFDILMGQFAHNIENIWGFKEVVIAGPKDYVKYTDQYQTRSHINFDDGTITIETIAGTEPAAHLRRAIIKTLLMGDDPSSVDLYSDVDDITISKEPFLYGQVVDNTGQPIRWEGRASNFADYLLKNRLQSRSNGLRIIYSVTINMVPNHLDKRAHKYLGMVRQASRKYGVDESLILAIMQTESSFNPYAVSRSDALGLMQVVQHTAGKDVFRSQGKSGTPSRSFLFDPASNIDTGTAYLAMLNNVYLGGIDNPTSRRYAVITAYNGGAGSVLRVFSNDKIQAANIINTMTPGDVYQTLTTRHPSAESRRYLYKVNTAQKSYRRR
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase C, Murein lyase C.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RIMK_SALPC
Sequence: MKIAILSRDGTLYSCKRLREAAMRRGHLVEILDPLSCYMNINPAASSIHYKGRRLPHFDAVIPRIGSAITFYGTAALRQFELLGSYPLNESVAITRARDKLRSLQLLARQGIDLPITGIAHSPDDTSDLIKMVGGAPLVVKLVEGTQGIGVVLAETRQAAESVIDAFRGLNAHILVQEYIAEAKGCDIRCLVVGNEVVAAIERCAKAGDFRSNLHRGGVASIATITPRERDIAIKAAQTLGLDVAGVDILRAARGPLVMEVNASPGLEGIEKTTGVDIAGRMIQWIERHATPEFCLKIGG
What is the function of this protein?
Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF).  Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate.  The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH.
What are the official names of this protein?
Ribosomal protein S6--L-glutamate ligase, Poly-alpha-glutamate synthase, Ribosomal protein S6 modification protein.
What is the protein family that this protein belongs to?
Belongs to the RimK family.