PharMolix/UniProtQA huggingface dataset:
Protein: NRDR_ANAMM
Sequence: MRCPFCNSVDTSVKNSRPSDCKMSVRRRRSCDSCNSRFTTVEELLLKPVKVLKKDGSVEAFDRQKLLTSIILATKKRPVTRDQIDMVVSNMFYKLEAIKGSVVPSGVIGGMVMESLFALDKVSYIRFASVYMNFSDVNDFSGIVERVQEVV
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: NOSO_STAAU
Sequence: MLFKEAQAFIENMYKECHYETQIINKRLHDIELEIKETGTYTHTEEELIYGAKMAWRNSNRCIGRLFWDSLNVIDARDVTDEASFLSSITYHITQATNEGKLKPYITIYAPKDGPKIFNNQLIRYAGYDNCGDPAEKEVTRLANHLGWKGKGTNFDVLPLIYQLPNESVKFYEYPTSLIKEVPIEHNHYPKLRKLNLKWYAVPIISNMDLKIGGIVYPTAPFNGWYMVTEIGVRNFIDDYRYNLLEKVADAFEFDTLKNNSFNKDRALVELNYAVYHSFKKEGVSIVDHLTAAKQFELFERNEAQQGRQVTGKWSWLAPPLSPTLTSNYHHGYDNTVKDPNFFYKKKESNANQCPFHH
What is the function of this protein?
Catalyzes the production of nitric oxide.
What are the official names of this protein?
Nitric oxide synthase oxygenase, NOSoxy-like protein, SANOS.
What is the protein family that this protein belongs to?
Belongs to the NOS family. Bacterial NOS oxygenase subfamily.
Protein: RS14_STAEQ
Sequence: MAKKSKIAKEQKRQELVNKYYELRKELKAKGDYEALRKLPRDSSPTRLTRRCKVTGRPRGVLRKFEMSRIAFREHAHKGQIPGVKKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: ARGD_HAEDU
Sequence: MTSDQIKQLDANYIAQTYAKFDLALSHGQGCEVWDFDGNKYLDFTSGIGVNSLGWADPDWLEAVIAQLHKLSHTSNLFYTEPSARLAKHLVQVSGLKRVFFANSGAEANEGAIKVARKYSHDKYGDTRSTIISLVNSFHGRTISTLAATGQKLFHQHFFPFTAGFEHLIANDLNAFKTRIAQNDICAIILEVVQGEGGVCSLDQAYLQAVQGLCQVQDILLIIDEVQTGIGRTGTMFAYQQFELKPDIVTLAKGLAGGLPIGAFLLADKVAETLAKGDHGSTFGANPVSCAAANAVLTKLEPLFLTEVMRKGQKLRKALQSLPHVKSISGLGLMIGVEFDEHINVADVVTNCLKQGVLFLTAKTKLRMLPPLIINDEQLERGVTVLAQVLSEM
What are the official names of this protein?
Acetylornithine aminotransferase, ACOAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XKR7_HUMAN
Sequence: MAAKSDGAAASASPDPEGAAGGARGSAGGRGEAAAAAGPPGVVGAGGPGPRYELRDCCWVLCALLVFFSDGATDLWLAASYYLQNQHTYFSLTLLFVLLPSLVVQLLSFRWFVYDYSEPAGSPGPAVSTKDSVAGGAAISTKDSAGAFRTKEGSPEPGPQPAPSSASAYRRRCCRLCIWLLQTLVHLLQLGQVWRYLRALYLGLQSRWRGERLRRHFYWQMLFESADVSMLRLLETFLRSAPQLVLQLSLLVHRGGAPDLLPALSTSASLVSLAWTLASYQKVLRDSRDDKRPLSYKGAVAQVLWHLFSIAARGLAFALFASVYKLYFGIFIVAHWCVMTFWVIQGETDFCMSKWEEIIYNMVVGIIYIFCWFNVKEGRSRRRMTLYHCIVLLENAALTGFWYSSRNFSTDFYSLIMVCVVASSFALGIFFMCVYYCLLHPNGPMLGPQAPGCIFRKASEPCGPPADAITSPPRSLPRTTGAERDGASAGERAGTPTPPVFQVRPGLPPTPVARTLRTEGPVIRIDLPRKKYPAWDAHFIDRRLRKTILALEYSSPATPRLQYRSVGTSQELLEYETTV
What are the official names of this protein?
XK-related protein 7.
What is the protein family that this protein belongs to?
Belongs to the XK family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YDHK_BACSU
Sequence: MSAGKSYRKKMKQRRMNMKISKYALGILMLSLVFVLSACGNNNSTKESTHDNHSDSSTHEEMDHSGSADVPEGLQESKNPKYKVGSQVIINTSHMKGMKGAEATVTGAYDTTAYVVSYTPTNGGQRVDHHKWVIQEEIKDAGDKTLQPGDQVILEASHMKGMKGATAEIDSAEKTTVYMVDYTSTTSGEKVKNHKWVTEDELSAK
What are the official names of this protein?
Uncharacterized protein YdhK.
Protein: TMCAL_STRPF
Sequence: MTVTGIIAEFNPFHNGHKYLLETAEGLKIIAMSGNFMQRGEPALIDKWIRSEMALKNGADIVVELPFFVSVQSADYFAQGAIDILCQLGIQQLAFGTENVIDYQKLIKVYEKKSKQMTAYLSTLEDTLSYPQKTQKMWEIFAGVKFSGQTPNHILGLSYAKASAGKHIQLCPIKRQGAAYHSKDKNHLLASASAIRQHLNDWDFISHSVPNAGLLINNPHMSWDHYFSFLKYQILNHSDLTSIFQVNDELASRIKKAIKVSQNIDHLVDTVATKRYTKARVRRILIYILVNAKEPTLPKGIHILGFTSKGQAHLKKLKKSRPLITRIGAETWDEMTQKADSIYQLGHQDIPEQSFGRIPIIIKKERLN
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALLC_RHIME
Sequence: MTRAGEVLPGFAGGTINLASAGLGARALFATDEFFGPLERMLKDEPAAFHPGLYDDHGKWMDGWETRRRRGAGHDYAVIALAAKGRIAGFDVDTSHFTGNYPSACSIEACHSAEDPDEATEWVQLLPVTGLGPNAHHFFAAHSDAVYSHIRLRIHPDGGIARLRVYGTPALDLKAMANETIDLASCLLGGRIVAFSNGHYGHERLIAPGRGANMGDGWETRRRREPGYDWIIVKLAARGHVERILVDTAHFKGNYPDACSLQAADLGGMTAECDMLVASSAMFWNELLPHRKLSADSVHEYGSDMLRHADPVTHVRLNIYPDGGVSRLRIYGRVADPRSR
What are the official names of this protein?
Probable allantoicase, Allantoate amidinohydrolase.
What is the protein family that this protein belongs to?
Belongs to the allantoicase family.
Protein: BDBC_CHLPN
Sequence: MINFIRSYALYFAWAISCAGTLISIFYSYILNVEPCILCYYQRICLFPLTVILGISAYREDSSIKLYILPQAVLGLGISIYQVFLQEIPGMQLDICGRVSCSTKIFLFSYVTIPMASVVAFGAIVCLLVLTKKYRG
What is the function of this protein?
Required for disulfide bond formation in some proteins.
What are the official names of this protein?
Probable disulfide formation protein, Disulfide oxidoreductase, Thiol-disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family. BdbC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YL075_MIMIV
Sequence: MLVMNIENFPPEILANISGFLTDKEFILLTTIDRFFYGLKKINKLKNPYDFKTIRTIIDEYLFSHLIIDSTDLFDILSKYNINTITLSDNFNGDIKMFYSLPNLNKIHVGLNYTDVDSITGIPDKIINKKEIILTLVSNKIAFDTYSKSLKRLEKKNFLKHTYPQIYNWESIYKIINKHFRIVFNALGKNFDSFTYKESYNLVKLILLFTDPKYKNVLTEYFSKFEILHKYQVLKFHPELRQCITKKNYHLPNFIKENSVIVKEFIYDIKFIHNHKFLYLKNTYEKIIKQHGFNNVNEYRDFLVKLNTHK
What are the official names of this protein?
Uncharacterized protein L75.
Protein: ATPG_ECO24
Sequence: MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRPYAETMRKVIGHLAHGNLEYKHPYLEERDVKRVGYLVVSTDRGLCGGLNINLFKKLLAEMKTWTDKGVQCDLAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAYDEGRLDKLYIVSNKFINTMSQVPTISQLLPLPASDDDDLKHKSWDYLYEPDPKALLDTLLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQELTEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RDRP_I57A5
Sequence: MDVNPTLLFLKVPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSEKGKWTTNTETGAPQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLEESHPGIFENSCLETMEVIQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVFRSNGMTANESGRLIDFLKDVIESMDKEEMEITTHFQRKRRVRDNMTKKMVTQRTIGKKKQRLNKRSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTELSFTITGDNTKWNENQNPRMFLAMITYITRNQPEWFRNVLSIAPIMFSNKMARLGKGYMFESKSMKLRTQIPAEMLASIDLKYFNESTRKKIEKIRPLLIDGTVSLSPGMMMGMFNMLSTVLGVSILNLGQKKYTKTTYWWDGLQSSDDFALIVNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSYINRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMINNDLGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRSFELKKLWEQTRSKAGLLVSDGGPNLYNIRNLHIPEVCLKWELMDEDYQGRLCNPLNPFVSHKEIESVNNAVVMPAHGPAKSMEYDAVATTHSWIPKRNRSILNTSQRGILEDEQMYQKCCNLFEKFFPSSSYRRPVGISSMVEAMVSRARIDARIDFESGRIKKEEFAEIMKICSTIEELRRQK
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: YR741_MIMIV
Sequence: MVLKNIWRKNKIFDKENLSRELKCYKYANKFIKKRSNKIERKLSQNIFDDIIEKQTKDNRSGNLAVIFVESFHETELHVCQLNQESESIGQLIKEFNRIKYHIENNVDFIEEFEKHLYEMDRYDEYIKQYTFNKDSVLKYIEDNIELIMREKYEWQKQLEYFDMKLKLVRYVLYHFPKIYAQ
What are the official names of this protein?
Uncharacterized protein R741.
Protein: RUVC_FRATW
Sequence: MVILGIDPGSRITGFGVIKVQDNKIYYVASGCIRITEITTPKRLKQIADGITQIINIYAPTEAAIEQIFMFQNPMGAIKLGQARGVAMCTLAINNLEVSEYSAKQIKQAVVGTGGAAKSQVQHMVQSLLGLSKKPPEDAADALAIAICHYHSSKSLAKISGASRVSQKRIK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: MSHB_MYCUA
Sequence: MPETPRLLFVHAHPDDESLSNGATIAHYAARGAQVHVVTCTLGEEGEVIGDRWAQLAVDHADQLGGYRIGELTAALQRLGVDAPIYLGGAGRWRDSGMAGTEQRSRRRFVDADDREAVGALVAIIRELRPHVVVTYDPDGGYGHPDHVQAHVVTTAAVAAAGSVGDCDYPGDPWVVPKFYWTVLGVSAFLAGRQALTPDDLLPEWVLPPEDIPFIYPDERIDAVVTGDSDARAAKIAALAAHATQVTVGPSGRACALSNNMALPILADEHYLLVAGRAGARDERGWEIDLLAGLGFTGFGT
What is the function of this protein?
Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
What are the official names of this protein?
1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, GlcNAc-Ins deacetylase, N-acetyl-1-D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase.
What is the protein family that this protein belongs to?
Belongs to the MshB deacetylase family.
Protein: PUR9_DEIRA
Sequence: MTKRALISVSDKTGVVEFAAQLQQRGWELLSTGGTFATLSGAGIPVRQVSDVTGFPEMLDGRVKTLHPAIHGGILARREAGHLGQLAAQDIGTIDLVCVNLYPFRETVARGAPDPEVIENIDIGGPAMIRSAAKNHDAVLVLVDPADYALALQDEVSPAERRRLAAKAYRHTSEYDAAITAYLSGESDELPTQLPEHLSLDLTRTAQVRYGENPHQPGAIYRWGNARGPVIDAQVVAGKPMSFNNYADADAAWSLCQELAAQEQGAVCVAVKHANPCGVAVAADVKTAWERARDADTLSVFGGVVAVSQPVDFGAAQSMKGTFLEVLIAPDVTPDAVEWFAAKKPDLRVLIAGQPQGVSVLDVRPLTGGFAVQERDARPWDDLCPEVVTERQPSEQEWADLRFAWAVVKGARSNAVALCKGGVTVGLGAGAVSRIWAAERAIANAGEAAQGAVLASEAFFPFDDVVRLAASAGVTAVLQPGGAKRDPEVIAACNELGISMVFTGSRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: ATG5_RAT
Sequence: MTDDKDVLRDVWFGRIPTCFTLYQDEITEREAEPYYLLLPRVSYLTLVTDKVKKHFQKVMRQEDVSEIWFEYEGTPLKWHYPIGLLFDLLASSSALPWNITVHFKSFPEKDLLHCPCKDAVEAHFMSCVKEADALKHKSQVINEMQRKDHKQLWMGLQNDRFDQFWTINRKLMEYPPEENGFRYIPFRIYQTTTERPFIQKLFRPVAADGQLHTLGDLLREVCPSAVAPEDGEKKSQVMIHGIEPLLETPLQWLSEHLSYPDNFLHISIVPQPTD
What is the function of this protein?
May play an important role in the apoptotic process, possibly within the modified cytoskeleton.  Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.  Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.
What are the official names of this protein?
Autophagy protein 5.
What is the protein family that this protein belongs to?
Belongs to the ATG5 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein. Note=The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme.
Protein: GPDA_CHLT2
Sequence: MKETIAYLGMGMWGFSLANLLANNGHRVVGWARNPALIEQLSVQRRHPAAPHISIPQNLSFTYHMEEALDGATMIVEGVTSAGMRPVLTQLKALTELRVPLVITSKGIEQNTGLLLSEIALEIFGRPAAQHLGYLSGPSIASEVLRGCPCSVVISAYNPDTLKQIHRAFLTPTFRVYPNSDLKGVALGGALKNVIAIACGISDGFRFGDNAKSGLVTRGLHEIRKFATIMGCRPDTLNGLAGLGDLCTTCFSAFSRNTLFGKLLAEGLTPEQAKTKIGMVVEGVYTALSAHQIATHHRIDMPITTSVYRVLYENLDIQEGIAQLLQRDTKEEYL
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_STRSY
Sequence: MNLKDYIATIPNYPKEGIEFRDISPLMADGNAYSYAVREIVQYATDKQIDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLTMHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGIVAGCAFLIELDDLKGREAIGDYDYKVLMHY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_CLONN
Sequence: MNSEKIFYDILNVAAENVDLEFNDKKYNQFIQYKDLLKDWNGKVNLTAITEDEEIIKKHFIDSMKIFQFEYLRKANKIIDIGTGGGFPGIPMKIMRPDADIVLLDSLKKRINVLDDILNKIGINDVETIHGRAEEFAKNPKYREKFDAVVSRAVANLASLSEFCLPYVKVGGYFVALKGPAVDEEVKIAKKAISILGGKLEEIREVEIEDSDLKHNLVIIKKIKNTPKQYPRKPGTATKKPLI
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2B_METKA
Sequence: MVEYDYEELLERAYEQLPEEVLEDRRFEMPKPKVSVEGKTTVIRNFKEISKKLDRDPEHITKYFLKELGTAGHVDGGRLILHGVYHPKLVEEELKNYVEEFVLCPECGKPDTKLVREDRQWILKCEACGAWSSVRRLK
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit beta, aIF2-beta, eIF-2-beta.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-beta/eIF-5 family.
Protein: TSN9_PIG
Sequence: MARGCLCCLKYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFATFSPSFPSLSAANLVIAIGTIVMVTGFLGCLGAIKENRCLLLSFFIVLLIILLAELILIILFFVYMDKVNENARKDLKEGLLLYNSENNVGLKNAWNIIQAEMHCCGVTDYTDWYPVLGENTVPDRCCMENSQGCGRNSTTPLWKTGCYEKVKMWFDDNKHVLGTVGMCILIMQILGMAFSMTLFQHIHRTGKKYDA
What are the official names of this protein?
Tetraspanin-9, Tspan-9.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Note=Colocalizes with GP6 in tetraspanin microdomains on the platelet surface.
Protein: GRPE_LISMH
Sequence: MSEKKNKKEKLADEIEQEELNILDETEETVEEEAAADTLTEEQAKILELENKLDEVENRYLRMQADFENVKKRHIADRDASQKYRSQSLAQDLLPALDSFEKALATTSDQEEVKQILKGMEMVYNQILVAFEKEGIEVIPAVGEQFDPNFHQAVMQDSDENAGSNEITAELQKGYKLKDRVIRPSMVKVNQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_SHEB2
Sequence: MSERAPVVTIDGPSGAGKGTISQLLAQHLGWQLLDSGAIYRVLALAAIHHNVELENEESITLLAAHLDVKFLTGNDTDPVQVILEGEDVTTDIRTQECSNAASKVAAFPRVREALLRRQRAFKTAPGLIADGRDMGTVVFPSAPAKLYLTASAEERAQRRYNQLQDKGFDVNIERLLSEIIERDDRDMNRPVAPLVPAEDALIIDTSGKGIDEVLALALNFINQKLSDTN
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_UREP2
Sequence: MDVINLIKNLKQILRTANNERHLIELKNIFVKQHLLPLYDELKKSANKKEMGLLINNFKQQIEFVTDQILKELNDKDDQVDLKKWTNKTLFAPFINNGHHHILNSIIDDIASFFKKLNFEIVSGSEVVSPIYNFDHLNIDENHPARASADSFFINSIKMLRTHCTTTTAQFLENNVNKDIRIMSFGNVYRKDDDDATHSHQFNQVDFVWVKEGLTVANLKWLIDSLIKYLFGQNLKTRYRLSFFPFTEPSFEVDVQCFKCDLKGCAVCKKSTWIEIMGTGMLHENVLKAANINDIRTGMAFGVGIDRIAMLKYEIDDIRYLYSNNFKFNAQIK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30E_METM6
Sequence: MRRRSSMDINRAIRVAVDTGNVVLGTKQAIKNIKHGEGQLVIIADNCAKDVREDIFYYTQLSETPVYTHQSTSIELGAICGKPFPVSALLVLEPGNSAILNVNNEE
What are the official names of this protein?
50S ribosomal protein L30e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL30 family.
Protein: SYY_LEPIC
Sequence: MDIQKQIEIIRRGTVDLISEEELKSKLQKKKTLKIKAGFDPTAPDLHLGHFVQLKKLKHFQDLGHEVSFLLGDFTAMIGDPTGKSETRKRLSREEVLENSKTYQNQVFKVLDPVKTKIVYNSNWCSKMNFEDVLVLSSKYNVARMLERDDFSKRYKAGQPISMIEFLYPLVQGYDSVAMECDVELGGTDQKFNLLVGRDLQREYGKEAQCVLTLPLLVGLDGSKKMSKSLGNYVGITETPIDMFGKLMSISDDLMWNYFELLTDLPLPEIENRKNGMAKKELHPKEIKTELAKLIMDQFSSPSENEEAIQEWKKIHNPKSRAVPDDVKEIKLGEEFFAETPEPLLVWVLSKLSFIPSVSEGRRLIKAGGLYLSEDKITDEKFPIQKGKEYLVRQGKKGKFLKIIS
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_CHLTA
Sequence: MSLSPSRIRLLDSVTVNQISAGEVIENAASVVKELIENSLDAGADEIHIETLGGGRGQIVVRDNGVGMDPEEVPVALQRHATSKIAHFADIFSLASYGFRGEALPSIASISKMEIHTARAGGLGSKTLIEKGEPVCCEPAPRQQGTTIAVHSLFYNVPMRQSFQKSPQMDRLAIRRLLENSVLSSEGIGWTWISECRQELYVAKKQGFIERVALVLGESFVQEAFFIDKQQGDLRVLGFLGSPNQHRSTRQGQRLFINNRAVESSFISKKVAEAYAWMIPAQRYPIFVLKLFLPPMWCDFNVHPQKTEVRLLQEGQISNLLVEAISEALLRRSPSLEETVLKVPTEKIPIENEGISVPSIRPAIVSAPLSCPTFSQQPYLKTEMATIVSRDSASSSLSVVEKVRFLTSLGKVLLVEDSEGVHVVFVQAARKHLFYVSLLSERLESRLACQTFLLPSSVQMTKLEADFLQMRLEALTALGIELSRISPDSFAIESAPPFIQEEELKEWIVALAQEGALHVGESFEQLVENTVQKLVFSRNARAFDYAWLDILWKLGKPEKAFDGEMIRRLVLDDDFM
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: RPIA_PARMW
Sequence: MADLQTQMKQAVADAAVEQIKDGMVLGLGSGSTAALMIKALGAKLASGELKDIVGVTTSFQGEVLAAELNIPLLSLNAVDRIDLAIDGADEVDPGFQLIKGGGACHVQEKLVAARADRFVVVVDSTKLVERLNLGFLLPVEVLPGAWRQVQQQLAALGGKAELRMAQRKAGPVVTDQGNLVLDVTMNGGISDPAALESTVNNIPGVLENGLFVDLVDEVLVGEITDGSAGVRSLEKRLS
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: Y2356_RHOPB
Sequence: MTILKWALIFFVVSVIVGVLGFTGISAASADVARILFYIFLVIFLVLLILGLTIFRA
What are the official names of this protein?
UPF0391 membrane protein RPC_2356.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SEPT8_PLEMO
Sequence: MAATDLERFSNAEAEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFETEEASHHESCVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVVGSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETSAFNRRKAAVEALQSQALHATSQQPLRKDKDKKK
What is the function of this protein?
Filament-forming cytoskeletal GTPase (By similarity).  May play a role in platelet secretion (By similarity).  Seems to participate in the process of SNARE complex formation in synaptic vesicles (By similarity).
What are the official names of this protein?
Septin-8.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Synapse. Cell projection, axon. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Presynapse. Note=Expressed in axons of immature neurons, localizes to synapses in mature neurons.
Protein: MSTN1_MOUSE
Sequence: MSEAGTPEGPIKKKRPPVKEEDLKGARGTLAKNQDIKSKTYQVMRDYEQAGSAAPSVFSRNRTGTETVFEKPKEGPAKSVFG
What is the function of this protein?
May be involved in the development and regeneration of the musculoskeletal system.
What are the official names of this protein?
Musculoskeletal embryonic nuclear protein 1.
What is the protein family that this protein belongs to?
Belongs to the MUSTANG family.
What are the subcellular locations of this protein?
Nucleus.