PharMolix/UniProtQA huggingface dataset:
Protein: RLMM_SERP5
Sequence: MNRLALYCRQGFEKECAAEITAKAAELEVFGFARVKDNSGYVLFECYQPDDADRLAKEIPFRELIFARQILVVGELLRDLPPEDRVSPIVGMLIGVVDRGGELRVEVPDTNESKELLKFCRKLTVPLRTAMREQKVLMARENKTRPVVHVFFIAPGCCYVGYSFSNNNSPFYMGIPRLKFPSDAPSRSTLKLEEAFHVFIPADEWDERLASGMHAVDLGACPGGWTYQLVQRSMMVHAVDNGPMAPSLMDTGQVTHHRADGFRYEPSSSKIYWLVCDMVEKPAKVTSLMIQWLVKGWCREAIFNLKLPMKKRYEEVSQNLLAIKEALDTAGISSEIHAKQLYHDREEVTVHVRRMWSAVAGRRDERD
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBC31_XENLA
Sequence: MQTTDLGNKEYGKIWHRKPSPSTNEGIIVNIVHVDASHLSKSTRFLQAAFDSAGDCFLAGDHLGNVYMFNLNRNRFDLVQKTMQACTAIAFNLHRKTEFLVALADNSVKCFDAGAKELVSWMRGHESAVTSISIHASGRYAVTTSSDTAQLWDLDTFQRKRKLNVRQSVGIQKVFFLPLSNTILSCFKDDSIFAWESDTLACKYQLPIPEDETKLHYKAFAITRDGRMLAAGGKSKNLHLWCLDSKQLFRIIQMPAKVRSVQQLEFLPDNFDGGSSQILGVLSQDGIMRFINIQTCKLVFDIGNPDNRVVTSSVSPNGRYITSVMENGSLNIYSVQALSKELNKPPPPLVKMVDLSKDKDSTGNKSGVSRASQEKVRVSSGRTCRPWKTKDPIVRTKYLRPEDTTASEDKENALPAGLNKPRLQAMLKGFGEYPAKYRMFIWRSLLQLPENHAAFSSLLDKGTHSQYKLLHQEYPIKSRKLLRVLQRTLSALAHWSAIFGETKYLPLLAFPFVKLFQNNQLICFEVVATVITNWCQHWFEYFPNPPINILGMVENLLAHHDKELLQHFINHGVNSQVYAWPILETLFSEVLTREEWLRLFDNVFSNHPSFLLMAVVSYIISSRSPLLHCNQKDDFEYFFHHRNNLDISNMIREAYHLMDTSPAEIHPQRLLSDFEPLTRGQYPIFNKYPKFIVDYQGQERERIRQEEMEYLRERQLTQEVEAEAVKRRLEDQAWYQQQELLKGAEEQRRKLLMDEEQKLLHQRQRLATVKRELRLKELQLLDAARRRFLRYQQDQRKMELRRLDDEIERKVSLREQETATIVKDVEIRQMELEAQRRFFEQQLAKEQEAVTQDMKGELDANRRRADLEEQMFWRLMETEEDLKDQKLLEESLAKAERLCVETDWKIQSLQKQKCDDWERGKRYEEISKLTEDVQEKERELCNVLKDMETRKWAEVSQKMTELEREKLAGSAQQAQRQQFLQEKLRQEAGPIDISGEDGNEYFERLRDLNRSSMQKDFSSSDEQHVPENVCLNDVSASDSSTHFSLDRGRGELERGERALISEVRELRQKLASQAHKKYPHLHFSQTSWS
What is the function of this protein?
Molecular adapter which is involved in cilium biogenesis.  Part of a functional complex including OFD1 a centriolar protein involved in cilium assembly.  Could regulate the cAMP-dependent phosphorylation of OFD1, and its subsequent ubiquitination by PJA2 which ultimately leads to its proteasomal degradation.
What are the official names of this protein?
TBC1 domain family member 31.
Protein: RNPA_MESFL
Sequence: MKNKKIIKKNFEFQEIISKQEFHRNSAFVIYYSKNDKGYFRYGISVGKKLGNAVTRNKIKRQIRMMIQDQIKILPEFSYDIVIIARNRMMQNSFDQNQKELNKLVVRFLK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: ARGC_METM6
Sequence: MKTVSIIGGTGYTGSELLRLLSNHDNVEVLNVTSRKEAGKKLTDFHPQVRNLRNYNDLEFQNIAPEDIDTDIVFCATPHGASMAIVPILHEKGINVIDLSGDYRFEDIEMYESWYGLKHTGIIESAVYGLPELHREKIKKSKTIANPGCYPTGAILSMAPLVANDLVDERIIFDSKSGVSGAGVVASQTTHFPNVNENLGAYKITNHRHSPEIGKELDYLGNKKLKVSFTPHLLPVTRGILTTAHSYLKEDVSRADVIEIYEEFYKDEFFVRIFEEGMVSLTGVRGTNFCDIGGFEIDQHGRIVVISAIDNLVKGASGQAIQNMNIIMGFDEKEGLSVGGMRP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDX2_BOVIN
Sequence: MPVMAASVAWGGVNAGFLLRAARGAWWSRPGGFWGSGEAAAPAIARKFRATGSRPAGEEEAGGPERPGDVVNVVFVDRSGQRIPVSGRVGDNVLHLAQRHGLDLEGACEASLACSTCHVYVSEDHLDLLPPPDEREDDMLDMAPLLQENSRLGCQIVLTPELEGAEFTLPKITRNFYVDGHVPKPH
What is the function of this protein?
Electron donor, of the core iron-sulfur cluster (ISC) assembly complex, that acts to reduce the persulfide into sulfide during [2Fe-2S] clusters assembly on the scaffolding protein ISCU (By similarity).  The core iron-sulfur cluster (ISC) assembly complex is involved in the de novo synthesis of a [2Fe-2S] cluster, the first step of the mitochondrial iron-sulfur protein biogenesis.  This process is initiated by the cysteine desulfurase complex (NFS1:LYRM4:NDUFAB1) that produces persulfide which is delivered on the scaffold protein ISCU in a FXN-dependent manner.  Then this complex is stabilized by FDX2 which provides reducing equivalents to accomplish the [2Fe-2S] cluster assembly.  Finally, the [2Fe-2S] cluster is transferred from ISCU to chaperone proteins, including HSCB, HSPA9 and GLRX5 (By similarity).
What are the official names of this protein?
Ferredoxin-2, mitochondrial, Adrenodoxin-like protein, Ferredoxin-1-like protein.
What is the protein family that this protein belongs to?
Belongs to the adrenodoxin/putidaredoxin family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: ARGJ_ASPFC
Sequence: MVSPAQPAAAMAAFARMAKGQVRNYSAPLDMAIPASKQKYIPSSGSYPKGFLVSGTHVGVKASNTKFPDLALISSETPCSAAAVFTTNKFQAAPVQVSKKTLESRQGQGIRSVVINSGCANAVTGKGGLEDAVNMGKKVDECNGLSEPSTIVMSTGVIGQRLPISKILNKIPTAHENLASTHDAWLTTARAICTTDTFPKLLSRTFALPSSPGRTYSLAGMTKGAGMIHPNMATLLGVLCTDAPIDPSALQSLLTHAVSRSFNSISVDGDTSTNDTVAILANGAAGGAPISSPASDDYTAMQEILTSFAQSLSQLVVRDGEGATKFVTVRVQNSPDYESARLIASTIARSPLVKTALYGRDANWGRILCAIGYTQGVAPGTVVPERTSVSFKPVDGSPVLKLLVNGEPEQVDEERASVILQEEDLEIVVDLGGGEKGEQGLGGEEAVYWFCDFSHEYVTINGDYRT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: BNIP3_CAEBR
Sequence: MLDIKKKINFANVSGEKTDESSSSSAQQSSEQQQAAQPLAPQQTTPTAKATNPFITPMTESTPGMSESWVELAPSRTSLCSSVDINMVIIDEKDKDSRLSPVSIAQSPHVEFESLEQVKYKLVREMLPPGKNTDWMWDWSSRPENTPPKTIRMVQYGSNLTTPPNSPEPEMSQYMPYESDSLFNVRVVFGFLVTNIFSFVVGAAVGFAVCRKIIKHHRHY
What is the function of this protein?
Initiates apoptosis in a BH3-independent mechanism possibly by recruiting ced-3 to mitochondria and other cytoplasmic membranes.  Has a role in lifespan and tumor growth (By similarity).
What are the official names of this protein?
BNIP3 homolog, CbBNIP3, Daf-16/FOXO controlled germline tumor affecting.
What is the protein family that this protein belongs to?
Belongs to the NIP3 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: YR080_MIMIV
Sequence: MSKYMGGKEASSVLGVHQRTLYQWDKKGWIKTIRTKGGKRLYDVGSYLADKDEESKEDHKLSICYVRVSSNSQKDDLERQIKFMKKKYPNHTIIKDISSGINMNRKGLNKIIDLAIEGRIKEVVVAYKDRLAIFGFSLIERLIETYSDGKIVVVRKKENQEPQEELIEDMMDVMNVFTARRNGSRKYSNK
What is the function of this protein?
Resolvase catalyzes the resolution (a site-specific recombination) of the cointegrated replicon to yield the final transposition products.
What are the official names of this protein?
Putative resolvase R80.
What is the protein family that this protein belongs to?
Belongs to the site-specific recombinase resolvase family.
Protein: TRMB_HELAH
Sequence: MPHFLAKLDCKPLEYPIISGDFCFHKEFSSLKHPTKSCVYASFKDHIFLLQKIRRANDFLIKSEKATPLKREILKQALRIYAQSFEVILHNLQENSKHASGKKALDLEDFEDFIKENQAPILMEIGFGSGRHLMELAKNNPTKTCLGIEIYTPSIAQVLKQIELLDLKNLHVLQGDGRLVLESIPHHKCEKIFVHFPVPWNDKKHRRVLSERFLDEALRVLEPNGFLELRTDDTLYFEDSLKLALKHFKSEIEIKKNAQIPVVSKYEARWNKLKKDIYDLRIYSLESNETPFNNHAFDFSFDTITLNQKSVGMILKTPKIIKEGYFVHVCNIYENKGDFLVELSMGDFDWPMRLFVLSVKNQVFYLNKSPLKTLNNHKAHLLLQNILKEFDEYNHCSE
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: DHE5_YEAST
Sequence: MTSEPEFQQAYDEIVSSVEDSKIFEKFPQYKKVLPIVSVPERIIQFRVTWENDNGEQEVAQGYRVQFNSAKGPYKGGLRFHPSVNLSILKFLGFEQIFKNALTGLDMGGGKGGLCVDLKGKSDNEIRRICYAFMRELSRHIGKDTDVPAGDIGVGGREIGYLFGAYRSYKNSWEGVLTGKGLNWGGSLIRPEATGFGLVYYTQAMIDYATNGKESFEGKRVTISGSGNVAQYAALKVIELGGIVVSLSDSKGCIISETGITSEQIHDIASAKIRFKSLEEIVDEYSTFSESKMKYVAGARPWTHVSNVDIALPCATQNEVSGDEAKALVASGVKFVAEGANMGSTPEAISVFETARSTATNAKDAVWFGPPKAANLGGVAVSGLEMAQNSQKVTWTAERVDQELKKIMINCFNDCIQAAQEYSTEKNTNTLPSLVKGANIASFVMVADAMLDQGDVF
What are the official names of this protein?
NADP-specific glutamate dehydrogenase 2, NADP-GDH 2, NADP-dependent glutamate dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
Protein: C3H69_ARATH
Sequence: MSKRILCKFFAHGACLKGEHCEFSHDWKDPTNNICTYYQKGICSYGSRCRYEHVKASRPHPSASSSSAVPRPSPASASNTLACAFLPGVAERDLSPVPSSSLKPTWNLDSLHQDSVDEVKTSNPGTVKPEELPICSFAAAGDCPRGNECPHIHGTICPTCGKCCLHPFRPDEREEHKKVCEKKHKQLEALKLSQEIECCVCLERVLSKATPAERKFGLLTECDHAFCIACIRNWRSSSPSTGMDVNSTLRACPICRKLSYFVVPSVIWFSAPEEKKEIMDNYREKLRSIDCKHFSFGDGNCPFGTSCFYKHAYHDGRLEEVVLRHLDAEDGQTVIAKDIRLSDFLENMHI
What are the official names of this protein?
Putative RING-type E3 ubiquitin transferase C3H69, Zinc finger CCCH domain-containing protein 69, AtC3H69.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPA_DICT6
Sequence: MKEEVLGLPIEKIQEKIKEYDFSPRISNIGYVKSVGDGVAQVSLLNAAFVGEIVIFESGIQGMVLSLKEDSVGVILFGRDEYVKEGEVVYSTGKILQVPTGSGFLGRVIDPLGNPIDGGGLIFPEAYVPVDNEAPSIFDREPVKEPLYTGIRAIDALIPIGHGQRELILGDRQTGKTTIAIDTIISQRNYGTICIYVAIAQKRTNIARIVQTLREYGALSNTIVIATFPDDPPALRYIAPMAGCAMGEYFMRQGERVLIVYDDLTKHANTYREVALLLRRVPGREAYPGDIFYLHSHLLERAAKLSRKLGGGALTALPIAETLAGEISTYIPTNLISITDGQIYLDTALFNAGVRPAINVGLSVSRVGGSAQPKGMRQVAGRLRLDLAQYREYAMFLEFGTELDMATKKKIERGRRIEELLKQGAHEVQSVEEQIITFYLANGGFLDNYPVEKVKDVVIKYIAYLKLKYSSVLTLLREQLELSDQIIYQIHNIFQEFEREVYANPSNPQA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYFA_BRUA2
Sequence: MSDLEQLERQILEDIAAAVDEQGIEAVRVAALGKKGTVSEKLKTLGGMSPEERQMQGPAINGLKNRVTEALSERRTELRKAAVAARLEREKVDVTLPVRESAASRGRIHPISQVIDEITAIFADMGFSIAEGPDIETDYYNFTALNFPEGHPAREMHDTFFFNPDEKGERKLLRTHTSPVQVHTMEKFAAMRDKEGRDEPIRIVIPGKTYRMDSDATHSPMFHQVEGLVVDKSANVANMKWVLEEFCKAFFEVPSVKMRMRPSFFPFTEPSVEVDIQCDRSGPHVKFGEGNDWLEILGCGMVHPNVLRMSGYDPEVYQGFAWGMGIDRIAMLKYGMPDLRAFFDADVRWIEHYGFRPLDIPTLFGGLSA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRD5_XENLA
Sequence: MYQPFQHLDSDQVASWQSPEMLMNKSVSRESQRRKELVAGQIVTGSLLLLLIFWTLFGNILVCTAVMRFRHLRSRVTNIFIVSLAVSDLLVALLVMPWKAVAEVAGHWPFGAFCDIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTQRVALLMISTAWALSVLISFIPVQLSWHKSETEDHLLSNHSTGNCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQIQIKRISTLERAAEHAQSCRSNRVDSCSRHHQTSLRTSIKKETKVLKTLSIIMGVFVCCWLPFFILNCMVPFCDRSPGHPQAGLPCVSETTFDIFVWFGWANSSLNPIIYAFNADFRKVFSSLLGCGHWCSTTPVETVNISNELISYNQDTLFHKDIVTAYVNMIPNVVDCIDDNEDAFDHMSQISQTSANNELATDSMCELDSEVDISLHKITPSMSNGIH
What is the function of this protein?
Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
What are the official names of this protein?
D(1B) dopamine receptor, D(5) dopamine receptor, Dopamine D5 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NDHJ_LIRTU
Sequence: MQGRSSAWLVKHELVHRSLGFDYQGIETLQIKPEDWYSIAVISYVYGYNYLRSQCAYDVAPGGLLASVYHLTKIEYGVDQPEEVCIKVFAPRRNPRIPSVFWIWKSADFQERESYDMLGISYENHPRLKRILMPESWIGWPLRKDYIAPNFYEIQDAY
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, chloroplastic, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: Y458_CHLTB
Sequence: MTKLPYALLDKGSLLVASPDVNGGIFSRSVVLLCEHSPNGSFGLILNKILEIDSPEEIFPLDHFDESKVRFCMGGPLQANQIMLLHTSPDSANSSIEICPSVFLGGDFSFAGEKEGRTRDDKMLLCFGYSGWQGGQLEKEFLEGLWFLAPSSQEIIFTDAPERMWSDVLQHLGGRFASLSTIPENLLLN
What are the official names of this protein?
UPF0301 protein CTLon_0458.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: RIMP_RHIWR
Sequence: MADIAALTKLIEPEAKALGLDLVRVAFFGGKSDPTLQVMAERPDTRQLDIADCEALSRRISDKFDELDPIEDAYRLEVSSPGIDRPLTRVKDWADWSGFDARVKLAAPLDGRKQFDGRIVASDGDSVTLGVNKLGEVTVPLAQIASAKLILTDALIKATAPLSTEGVDQIVEDAPHRGAGKIQLEG
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_DEIRA
Sequence: MSGVRLTVLGSTGSIGTQTLDVARQRGYTVGTLAAGRNLDLLAEQVREFRPALVSVDGSILAEARERLSGVRVIADPSEAAVAQADVVVNAMSGLIGLPPTRAALEAGQAVALATKEAMVTSAHLMWEAAAAGGGRVVPVDSEHTGVYQCLTGEDMGDVAELILTASGGPFRDGPADLSAVTPEQALKHPSWSMGPKVTIDSATLMNKGLEVMECASLYGLPLSQVGVVVHPQSIVHAAVRLRDGSLKAQFGPADMRLPIAYAIDAAPSGMQHPGDVRGARRGEEVGEHLGWPLLGQWEFRAPDLTRFPCLALAYRAGEAGGLLPVALNAADEVAVDAFLHGRIGFLDIPQLIERVLDETPGGALTWDSLTETDAWARARAQELCAYGVGGAGVGA
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: PCP_STACT
Sequence: MKILITAFDPFGGEKKNPALEAIKLLPEQIKNHQITKLEIPTVFHKSSDKIADKLKAEHFDAVIAIGQAGGRYNLTPERVGINIDDARIPDNENNQPIDIPIQQDGAPAYFSNLPVKKMTQAIKDAGIPAALSNTAGTFVCNHILYQLGYLQATRYPDIKFGFIHVPFIPEQVVDKPDKPSMALSSIVTGLEAAIGAISEDNQDIKEALGEIQ
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_CAMC5
Sequence: MHQTITEKIFSDHVGREVFANEIIESGIDMVIGNDITTPISIKQFERSGATKLANPEGFCIVMDHYIPAKDILSANQAKISRDFAYKHDLKYFFDEKDMGIEHALLPEKGLIVPGDVIIGADSHTCTHGALGAFSTGMGSTDLAYAMITGKNWFKVPPTIKVVFRGKLGRHVYGKDLILEIIRQIGVDGARYKALEFCGETIDALDMDGRFSMCNMAIEAGGKSGIIAVDETTREFLKGKNLRAEPKFFYSDEGAGYERVLEIYADKLDPVIAYPFLPSNGKSVREAVKDDIAIDQAFIGSCTNGRLSDLRIAAEILKGRKVSRKTRLIITPATQKIALAAQKEGLMDIFVEAGAVVSNPTCGACLGGYMGILGAGERCVSTTNRNFVGRMGDRTSEVYLANSAVAAASAIAGKIADPREL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: LMP2_EBVA8
Sequence: MGSLEMVPMGAGPPSPGGDPDGDDGGNNSQYPSASGSSGNTPTPPNDEERESNEEPPPPYEDPYWGNGDRHSDYQPLGTQDQSLYLGLQHDGNDGLPPPPYSPRDDSSQHIYEEAGRGSMNPVCLPVIVAPYLFWLAAIAASCFTASVSTVVTATGLALSLLLLAAVASSYAAAQRKLLTPVTVLTAVVTFFAICLTWRIEDPPFNSLLFALLAAAGGLQGIYVLVMLVLLILAYRRRWRRLTVCGGIMFLACVLVLIVDAVLQLSPLLGAVTVVSMTLLLLAFVLWLSSPGGLGTLGAALLTLAAALALLASLILGTLNLTTMFLLMLLWTLVVLLICSSCSSCPLSKILLARLFLYALALLLLASALIAGGSILQTNFKSLSSTEFIPNLFCMLLLIVAGILFILAILTEWGSGNRTYGPVFMCLGGLLTMVAGAVWLTVMTNTLLSAWILTAGFLIFLIGFALFGVIRCCRYCCYYCLTLESEERPPTPYRNTV
What is the function of this protein?
May be a negative regulator of isoform LMP2A.
What are the official names of this protein?
Latent membrane protein 2, Terminal protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae LMP-2 family.
What are the subcellular locations of this protein?
[Isoform LMP2A]: Host cell membrane; Multi-pass membrane protein. Note=Isoform LMP2A is localized in plasma membrane lipid rafts. SUBCELLULAR LOCATION: [Isoform LMP2B]: Host endomembrane system; Multi- pass membrane protein. Host cytoplasm, host perinuclear region. Note=Isoform LMP2B localizes to perinuclear regions.
Protein: CTR9_CAEEL
Sequence: MDESIDDVQETRTIAIPLKDSHEDEVIEINCSELPDGEEVLQILEAEEAKLSYWIEVALEYYRQDRVDLFMMILESAGSRAGLEYEGVKQDQMRALDILAAYWMTQGYREKAKDKKSDFFSKATVLFNTADKIAMYEWSHLTVRAWFYLFERDKSTNKYELADQQFNYVVKTNPKNVLPLIGKAVIAFNKKDYKTAIYYFRKAIRQCRHTIADLRVGIGHCFAKMGMMDKAKTAFERAMEIEPYNVSAMCGLGIILLNTYDHDSLKHAVSLFGRSYNLQTDHPVALIHLANHFFFKKEIERAWTLAWHAATYNDCDSIKAEAFYQMGRCRHAQGQFDGAYKYYYQARQANNGEHTLAHYGLGQMYIHRNEIEEAIKCFDTVHKRLPNNTDTMKILGSLYAHVQLNDPAQTAEARQKGRDVLGKYLAVENDDYEACIDLAQLLEATDPKRSLELYENAIDLLVTNESIQPQPEMLNNVGALYMSMKQYEKAEHHFKRAKERLEEQLNTDEGSLLLERRSAPEKSHLLTIRYNLALCLEHLCRTVEAEQMYKDIVKECPGYIDGYLRLGCITRDRHQVYESSLWLKQGVQFDQASPIVWTLIGNLHFAKNEWMPAQKKFEFILSKIFNNKIPDPYSLVALGNVWFEQLLNPSRKKEDEKKYIDRALQMYQKALKLQPKNMYAANGIGCVLAYKRNWNDARDVFSQVRESTSEFYDVWLNIAHVCMEREQWMAAVQMYSSAMKKFRKENDSTLQHYLAKAYYRANMLNEAKEALECAMLDQLDNTQLKFNYAIVLKKSAKEVLRGHKMTSEQVTAAIDDLKFADKIFQYISKNDDRQSSHTGMRISRTICAEEAKNCKDLLTQAKHKLAAAQTQDEEERRLMEKQEKEKIALQNKMIEEARAKEEAEKQKLEDMKNLRLSFIEMTKDVLRLPEIVEEKRRGGGGRKRRNDDGDEFVNDSSDAGNYDGEEGGEDGERRERRKKDKAAKKASRKKRERRDSGGPDSNRRDEKKRKRKEERDRKLQEKLSAKQSAKIKSRAFLSSSESSDDDKPKPAADSSDDEVDPRPPVDEFDSPTRTDSDSDRETTTKKKKKKAVVDSDEGSVSGSGSGSDNDDKPIIGGSDDDDDDKPAGGNSRDSDGSDAPKKKVIESDSD
What is the function of this protein?
Component of the PAF1 complex which is a multifunctional complex involved in transcription initiation via genetic interactions with TATA-binding proteins, elongation and transcription-coupled histone modification (By similarity).  Ctr-9 is required for epidermal microtubule organization during morphogenesis (PubMed:24721716).
What are the official names of this protein?
RNA polymerase-associated protein CTR9.
What are the subcellular locations of this protein?
Nucleus.
Protein: CP8B1_MOUSE
Sequence: MTLWCTVLGALLTVVGCLCLSLLLRHRRPWEPPLDKGFVPWLGHSMAFRKNMFEFLKGMRAKHGDVFTVQLGGQYFTFVMDPLSFGPIIKNTEKALDFQSYAKELVLKVFGYQSVDGDHRMIHLASTKHLMGQGLEELNQAMLDSLSLVMLGPKGSSLGASSWCEDGLFHFCYRILFKAGFLSLFGYTKDKQQDLDEADELFRKFRRFDFLFPRFVYSLLGPREWVEVSQLQRLFHQRLSVEQNLEKDGISCWLGYMLQFLREQGIASSMQDKFNFMMLWASQGNTGPTCFWVLLFLLKHQDAMKAVREEATRVMGKARLEAKKSFTFTPSALKHTPVLDSVMEESLRLCATPTLLRVVQEDYVLKMASGQEYQIRRGDKVALFPYLSVHMDPDIHPEPTAFKYDRFLNPDGTRKVDFYKSGKKIHHYSMPWGSGVSKCPGRFFALSEMKTFVLLMIMYFDFKLVDPDIPVPPIDPRRWGFGTSQPSHEVRFLYRLKPVQ
What is the function of this protein?
A cytochrome P450 monooxygenase involved in primary bile acid biosynthesis.  Catalyzes the 12alpha-hydroxylation of 7alpha-hydroxy-4-cholesten-3-one, an intermediate metabolite in cholic acid biosynthesis (By similarity).  Controls biliary balance of cholic acid and chenodeoxycholic acid, ultimately regulating the intestinal absorption of dietary lipids (PubMed:12393855, PubMed:28377401).  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH--hemoprotein reductase) (By similarity).
What are the official names of this protein?
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase, 7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase, CYPVIIIB1, Cytochrome P450 8B1, Sterol 12-alpha-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.
Protein: INT5_DICDI
Sequence: MKEEETIEISEKEKDKERNDNQDTLTISWIEDWRNEETATKNENNKNNNSDGDSDDDDYYDDDEEIKNSRYNLFLEKILTLESNSNLKNILSLNINFKKDNKKSKETDTAATTTTTTTTTTTTTTTTTPTATANKKYIRTNNLLNNNNSSSSSSSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGENITYITSPLSNESLESTEECCFFLVHLPITKDLIFNQFTCLLIHLFQIEYNNTIIINNATSSSSVNSLNRSYNNSNNNNNNNYNSYNNRGNNYNNNNQQQQQQQNPNLKIRDLEGYQDCSHLKKLCLTIHDYLTQLLQRNPLIWYDSIINWSLSTLTIITRLLIILKNNKSQQQQQQQQQQQQQQQQQQQQQQQTKNKTQFPPPPPPPLRQPITPISAMVRERLDFYSFRSLLSLVLHLTRIFSIETFIEKSNVTQFLDITSKSSSSSSSSSSSSSSSSSSSSSSSSSSSSSKTIKPKKLPIYELGWILCHLGKKNPSLILGLTFNHYLKNIGLNSNNNNNKVNSKSQYIQDINCFQILEFLALQPSSYLSIIFQQHIDKIISNHKSNKNKNNTQFLKDIKTFLMLITKDDVFLSIGLPIILDKLSPFGINQFDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNNSIKEDNSSEKDIESIKEILEKVLLGNSQVISFYSKRILLVLYHCCFGDSNDITFSSYSTSTLLQIKNQTRYNVSIKLLTSIVKDRLEKQLINKLYSPILNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQQQQQQSQEIENSTFINNLNQDENITFYLNQIQCNNNNNNNNNNNNNNNNKLIKEKNNIIIKLISLIGMDSIYSSLIILNHIISKLKSNQFIQYFYTLVEQFQAVNSNTIEFFINDLFKSIDSFSHDDLITLLNNLLELVKITPPPSSSSPSNLSIYNETLKCISSNWVVLLKLIKHPNLIESNKMMSIEILYHSFNNRYNNNNNNSQSIQQLEISNNNNNIKKKEIYPSTLLSDKEMLEIRVLLEKILNLIFKSFKEKNSFERLKKFEIYKNLYLLICNGSSVYFSSTIDLILDSLFSKKTDMIIKLPILCALSPANTLPPPNYPANLVNAGSGSGNFGNGDDDDDEYGDDEYGANRNEKEELYFKQIINPSLPLSQPLIMLPMQSSLLEINYERKYYHYKFNDMNNPNHIPFTNKPKNLKKRIENNQSSAIDTTNNNNKNNEILTYKKQRMKKKKQSIQQNGNINNEQQQEEDDNDDADDQNEQDDYEKYNILNNENDLQSFIKSLVLYDGGGGSGFNNHGDINDRLQILTNQFLLRVSSPYLEPSYENYQEILPKQSHYERDIFIRNLFQQNPFLYRVLEIISIDGRELTKCLEVIKSLLVNEISYWYQCRNSYSESPIKSSHYHTTILLVKALINAEFIIHPLNLSLELFDKIKAEEISYILTSIWNFIKDYQPNPSQYQSSSSSSSSSSPPSNNTIIPTFKRVFSNCNTTPYSLTLKAIFHNHIKELCFHYARFFPKKYY
What is the function of this protein?
May be a component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.
What are the official names of this protein?
Integrator complex subunit 5-like protein.
What is the protein family that this protein belongs to?
Belongs to the Integrator subunit 5 family.
What are the subcellular locations of this protein?
Nucleus. Membrane; Multi-pass membrane protein.