PharMolix/UniProtQA huggingface dataset:
Protein: LGT_PECAS
Sequence: MMTTSYLAFPQFDPVIFSIGPLALHWYGLMYLVGFVFAMWLAVRRANKPGSGWTKDEVENLLYMGFLGVFVGGRLGYVLFYAFPSFLENPLYLFKVWDGGMSFHGGLMGVICVMLWFAHRTKRHFFQVADFIAPLIPFGLGAGRLGNFINGELWGRVTTDTPWAMLFPGSRSEDMMLAVSNPQWQTIFNQFGMLPRHPSQLYQMMLEGVALFIILNLFIRKSRPMGSVSGLFLICYGMFRIITEFFRQPDAQLGLFGGLFSMGQILSLPMVLAGILMMVWAYRRQPAQQ
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MPRGA_DANRE
Sequence: MLNLIKLPQVFTINQVPKVFHEDGIISGYRHPCSSAKDCVLSLFQLTNETLNIWTHFLPTWFFLWKLLTVVLVLEDWRDPFIWPFLVFLLSCCVYPLASSCAHTFSTMSERARHICFFFDYGALSFYSLGSAIIYSSYSFPDKWVNGTFHLNYVSIAVVNSIISTALACYSRLGLPFLEYNCHSIKRPSGKLDQKLCKCLRIIAFVYPYLFDNIPLFYRIFVCAGEGCTVNEANTVHYQHTSLAFFTGFLFATHLPERLAPGSFDYIGHSHQLFHVFAIIGTYFQMTAIELDMAARKQWLHAHLPPVTFLNTVGAAFFSVVSGLCIVYVFSLSLFSTRGVKNKSF
What is the function of this protein?
Steroid membrane receptor.  Binds progesterone.  May be involved in oocyte maturation (By similarity).
What are the official names of this protein?
Membrane progestin receptor gamma-A, mPR gamma-A, Progestin and adipoQ receptor family member V-A.
What is the protein family that this protein belongs to?
Belongs to the ADIPOR family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PETG_AGRST
Sequence: MIEVFLFGIVLGLIPITLAGLFVTAYLQYRRGDQLDL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL18_RIPO1
Sequence: MKLSRKESVQRRHRRIRKKVNGTPNCPRLAVFRSNLHIYAQIIDDVGQHTIAAASTVEPDLKKSLSSGSTCEASAAVGKLVAERALAQGIEQVVFDRGGNLYHGRVKALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RL32_METKA
Sequence: MVRNPNLSKEEERLLKLREELKRKKPKFRRQEWHRYKKLGEKWRRPKGRHSKMRRKLKSKPKMPNPGYGSPKKVRGLHPSGYEEVLVYNPKDLEKIDPKRQAARIASRVGRRKRQEILEKAEELGIVVLNA
What are the official names of this protein?
50S ribosomal protein L32e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL32 family.
Protein: PEPX_STRTD
Sequence: MKFNQFSYIPVSPETAYQELRSLGFEVSLDASAKANFESFVRKYFLFFEDTDLALKNWIADPETDLLSFFQSDRPLTAEVFGLVALQLLGFVPNVDFTDSVAFLEKMAFPIAFDGSLNNLHQLLATRTQSGNTLIDQLVAQDLIPISNDYVFFNGKSLATFDTNQLHREVVYVETPVDTDKDGLLDLVKVTILRPNVDFPVPAMMTASPYQQGTNEPSSDKLTHKMEGDLLVKPAGKISLSRPEIKAPEADLTPINPVTKAEERFAHTDTYTLNDYMLARGVASIYVSGVGTFNSEGFMTSGDYQQVLAYKAVIDWLNGRARAFTSRSRQHTITADWASGKVTTTGLSYLGTMSNALATTGVDGLEMVIAEAGISSWYDYYRENGLLVSPGGYPGEDLDTLTEFTYSRALLAGEYLRHQKDYEAYLNELSTAIDRKHGDYNQFWHDRNYVQFADRVKATVVFTHGSQDWNVKPINVYQMFRALPKSLEKHLFFHNGAHVYMNAWQSIDFRESMNALICQKLLDLDNGYTLPTVIWQNNQSEQTWEVLDNFGHDNGKHIQLGKAEASIANHYEEEIFAKYGKAYQSFKDDLFMDKANAITLDFELDQDIQINGRVHLELRVKSSTNRGLISAQVLEMGDKKYLAPIPELKRMNVDNGRLFKEEALRELPFKQAKYRVITKGHLNLQNRKDLLSIENVTPNEWMTIGLDLQPTIYKLNKGDKLRLVLYTTDFEHTIRDNSDYEVTVDLSQSKMTLPY
What is the function of this protein?
Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
What are the official names of this protein?
Xaa-Pro dipeptidyl-peptidase, X-Pro dipeptidyl-peptidase, X-prolyl-dipeptidyl aminopeptidase, X-PDAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABL2_MOUSE
Sequence: MGQQVGRVGEAPGLQQPQPRGIRGSSAARPSGRRRDPAGRTADAGFNVFTQHDHFASCVEDGFEGDKTGGSSPEVLHRPFGCDAESQALNEAIRWSSKENLLGATESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTTDSKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTFKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECSREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFHDSSISEEVAEELGRTASSSSVVPYLPRLPLLPSKTRTLRKQGENKENLDGGLDAAESLASSSAPAGFIRSTQASSGSPALPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKRNAPTPPKRSSSFREMENQPHKKYELTGNFSPVASLQNADGFSVAPSQQEPNLVPAKCYGGSFAQRNLCADDDSGGGGGSGTAGGGWSGITGFFTPRLIKKTLGLRAGKPTASDDTSKPFPRSNSTSSMSSGLPEQDRMAMTLPRNCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSEEGAAPARERPKAKLLPRGATALPLRAPDPAITESDSPGVGVAGVAAAPKGKERNGGTRLGVAGVPEDGEQLGWSSPAKAVAVLPTTHNHKVPVLISPTLKHTPADVQLIGTDSQGNKFKLLSEHQVTSSGDKDRPRRVKPKCAPPPPPVMRLLQHPSTCSDPEEEPTAPPAGQHTPETQEGGKKAAPGPVPSSGKPGRPVMPPPQVPLPTSSISPAKMANGTAGTKVALRKTKQAAEKISADKISKEALLECADLLSSAITEPVPNSQLVDTGHQLLDYCSGYVDSIPQTRNKFAFREAVSKLELSLQELQVSSTAAGVPGTNPVLNNLLSCVQEISDVVQR
What is the function of this protein?
Non-receptor tyrosine-protein kinase that plays an ABL1-overlapping role in key processes linked to cell growth and survival such as cytoskeleton remodeling in response to extracellular stimuli, cell motility and adhesion, receptor endocytosis, autophagy, DNA damage response and apoptosis.  Coordinates actin remodeling through tyrosine phosphorylation of proteins controlling cytoskeleton dynamics like MYH10 (involved in movement); CTTN (involved in signaling); or TUBA1 and TUBB (microtubule subunits).  Binds directly F-actin and regulates actin cytoskeletal structure through its F-actin-bundling activity.  Involved in the regulation of cell adhesion and motility through phosphorylation of key regulators of these processes such as CRK, CRKL or DOK1.  Required for adhesion-dependent phosphorylation of ARHGAP35 which promotes its association with RASA1, resulting in recruitment of ARHGAP35 to the cell periphery where it inhibits RHO.  Phosphorylates multiple receptor tyrosine kinases like PDGFRB and other substrates which are involved in endocytosis regulation such as RIN1.  In brain, may regulate neurotransmission by phosphorylating proteins at the synapse.  Finally, functions as its own regulator through autocatalytic activity as well as through phosphorylation of its inhibitor, ABI1.  Positively regulates chemokine-mediated T-cell migration, polarization, and homing to lymph nodes and immune-challenged tissues, potentially via activation of NEDD9/HEF1 and RAP1 (PubMed:22810897).
What are the official names of this protein?
Tyrosine-protein kinase ABL2, Abelson murine leukemia viral oncogene homolog 2, Abelson tyrosine-protein kinase 2, Abelson-related gene protein, Tyrosine-protein kinase ARG.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. ABL subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: H2A_TRYCR
Sequence: MATPKQAAKKASKKRSGGRSAKAGLIFPVGRVGSLLRRGQYARRIGASGAVYMAAVLEYLTAELLELSVKAASQQAKKPKRLTPRTVTLAVRHDDDLGMLLKDVTLSRGGVMPSLNKALAKKHKSSKKARATPSA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RS12_STAMF
Sequence: MAGKKAPNGLFAARKLRRKRLKFRWSQREFKIKMLGLKKKHDPLEGAPMARGIVLEKVGVEARQPNSAVRKCVRVQLAKNGKVVTAFVPFDGGINYIDEHDEVIIEGIGGPRGRSMGDIPGVRYKVIMVNGVSLKALYLGKKQKPVR
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: EPHB_MYCTU
Sequence: MSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP
What is the function of this protein?
Could be involved in detoxification of extraneous host-cell epoxides.  Catalyzes the hydrolysis of epoxide-containing substrates.
What are the official names of this protein?
Epoxide hydrolase B, EHB, Epoxide hydrolase EphB.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.
Protein: FOLD_ACIBT
Sequence: MALVLDGRALAKQIEENLLVRVEALKAKTGRTPILATILVGDDGASATYVRMKGNACRRVGMDSLKIELPQETTTEQLLAEIEKLNANPDVHGILLQHPVPAQIDERACFDAISLAKDVDGVTCLGFGRMAMGEAAYGSATPAGIMTILKENNIEIAGKHAVVVGRSAILGKPMAMMLLQANATVTICHSRTQNLPELVKQADIIVGAVGKAELIQKDWIKQGAVVVDAGFHPRDGGGVGDIQLQGIEEIASAYTPVPGGVGPMTITTLIRQTVEAAEKALG
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: POT5_ARATH
Sequence: MDGEEHQIDGDEVNNHENKLNEKKKSWGKLYRPDSFIIEAGQTPTNTGRRSLMSWRTTMSLAFQSLGVVYGDIGTSPLYVYASTFTDGINDKDDVVGVLSLIIYTITLVALLKYVFIVLQANDNGEGGTFALYSLICRYAKMGLIPNQEPEDVELSNYTLELPTTQLRRAHMIKEKLENSKFAKIILFLVTIMGTSMVIGDGILTPSISVLSAVSGIKSLGQNTVVGVSVAILIVLFAFQRFGTDKVGFSFAPIILVWFTFLIGIGLFNLFKHDITVLKALNPLYIIYYFRRTGRQGWISLGGVFLCITGTEAMFADLGHFSVRAVQISFSCVAYPALVTIYCGQAAYLTKHTYNVSNTFYDSIPDPLYWPTFVVAVAASIIASQAMISGAFSVISQSLRMGCFPRVKVVHTSAKYEGQVYIPEINYLLMLACIAVTLAFRTTEKIGHAYGIAVVTVMVITTLMVTLIMLVIWKTNIVWIAIFLVVFGSIEMLYLSSVMYKFTSGGYLPLTITVVLMAMMAIWQYVHVLKYRYELREKISRENAIQMATSPDVNRVPGIGLFYTELVNGITPLFSHYISNLSSVHSVFVLISIKTLPVNRVTSSERFFFRYVGPKDSGMFRCVVRYGYKEDIEEPDEFERHFVYYLKEFIHHEHFMSGGGGEVDETDKEEEPNAETTVVPSSNYVPSSGRIGSAHSSSSDKIRSGRVVQVQSVEDQTELVEKAREKGMVYLMGETEITAEKESSLFKKFIVNHAYNFLKKNCREGDKALAIPRSKLLKVGMTYEL
What is the function of this protein?
High-affinity potassium transporter.  Can also transport rubidium and cesium (Ref. 1).  Is essential with AKT1 for high-affinity potassium uptake in roots during seedling establishment and postgermination growth under low potassium conditions (PubMed:20413648).  Mediates potassium uptake by plant roots in response to low potassium conditions, by a calcium-, CBL-, and CIPK-dependent pathway.  Positively regulated by the calcium sensors calcineurin B-like genes CBL1, CBL8, CBL9 and CBL10, and by phosphorylation by CIPK23 (PubMed:26474642).
What are the official names of this protein?
Potassium transporter 5, AtHAK1, AtHAK5, AtPOT5.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GSTM5_RAT
Sequence: MSCSKSMVLGYWDIRGLAHAIRMLLEFTDTSYEEKQYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLMDGKNKITQSNAILRYIARKHNMCGDTEEEKIRVDIMENQIMDFRMQLVRLCYNSNHESLKPQYLEQLPAQLKQFSLFLGKFTWFAGEKLTFVDFLTYDVLDQNRMFEPKCLDEFPNLKAFMCRFEALEKIAAFLQSDRCFKMPINNKMAKWGNKSIC
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
What are the official names of this protein?
Glutathione S-transferase Mu 5, GST class-mu 5.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Mu family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_SYNR3
Sequence: MTDQIPVVVAGALGRMGAEVIKAVHTAGDCQLVGAIDTCPGREGEDVGLALGLGELEVALTQDFEGALCLASQQHPGAVLVDFTHPKVVYEHTRAAIAYGVTPVIGTTGLAPEQLQELASFAAKASMGGAVIPNFSVGMVLLQQAAAAAARFYDHAELVELHHNRKADAPSGTCIKTAELMEELGKQFNAQEVEEHETLEGSRGGLRPSGLRLHSIRLPGLVAHQEVQFGGAGERYVLRHDTFDRAAYMPGVLLTVRKVRQLGALVYGLERLL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_KLEP3
Sequence: MQQRRPVRRALLSVSDKAGIVEFAQALTARGVELLSTGGTARLLADKGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDGIMQQHGIAPIDMVVVNLYPFAQTVAREGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIINEMDANEGSLTLNTRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESQEAAGRFPRTLNLNFIKKQDMRYGENSHQQAAFYIEENVKEASVATATQLQGKALSYNNIADTDAALECVKEFNEPACVIVKHANPCGVAVSNSILDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAIISRQFVEVIIAPSASEEALKITAAKQNVRVLTCGQWDARVAGLDFKRVNGGLLVQDRDLGMVTAGELRVVSKRQPSEQELRDALFCWKVAKFVKSNAIVYAKDNMTIGIGAGQMSRVYSAKIAGIKAGDEGLEVKGSAMASDAFFPFRDGIDAAAAVGITCVIQPGGSIRDDEVIAAADEHGIAMIFTDMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: RL1_METPB
Sequence: MAREGKRIRAAREGLEPTKLYAIDEAIKLVKSKASAKFDETVEISMNLGVDPRHADQMVRGVCNLPNGSGRTVRVAVFARGAKADDAKAAGADIVGAEDLLEIVQGGKIEFDRCIATPDLMPLVGRLGKVLGPRGLMPNPKVGTVTMDVKGAVAAAKGGAVEFRVEKAGIIHAGVGKVSFDEQKLVENIKAFADAVAKAKPAGAKGTYIQRIAVTSTMGPGVKVEPSTVLTA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: VMF7_MYXVU
Sequence: MDHGKYLLTIFLNDDDSFFKYLAAQEDDVAMSDVHTIVDYLNFLLALLIKSKDKLEAVGYYYAPLSEEYKAVFDFTDTKSLKQLFNKQPVYVESDSPICVDKGYLADFVLATTRLKKQLPLVLDKEVTYVDPYKDKRFANILSILHKN
What are the official names of this protein?
MF7 protein.
Protein: TCAL7_RAT
Sequence: MQRSCNEKEGKPKCSEPKREEEHPYGAFEGQRLEGNFRQRLLQSLEEFKEDIDYRHFKGEEMTGEEEEMERCLEEIRSLRKKFRALHSNRTHSRDRPF
What is the function of this protein?
Plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters.  Associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression.  Regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres)and telomerase-positive cell lines (By similarity).
What are the official names of this protein?
Transcription elongation factor A protein-like 7, TCEA-like protein 7, Transcription elongation factor S-II protein-like 7.
What is the protein family that this protein belongs to?
Belongs to the TFS-II family. TFA subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYB6_AGRST
Sequence: MSKVYDWFEERLEIQAIADDITSKYVPPHVNIFYCLGGITLTCFLVQVATGFAMTFYYRPTVTEAFSSVQYIMTEANFGWLIRSVHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVTGVVLAVLTASFGVTGYSLPWDQIGYWAVKIVTGVPDAIPVIGSPLVELLRGSASVGQSTLTRFYSLHTFVLPLLTAVFMLMHFPMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NFUA_XYLFA
Sequence: MIQISDRAKAHFLRLIQREGVPGMGVRLSAVDPGTARADARLEFAEPSELVGDEWLIDCGDFTLYVASASVAWLDSAEIDYVTQATGSQQLIIKAPKIKGQELSQVASLVERVCWVVENEINPQLASHGGRVEVQEVSAEGVVLLRFGGGCHGCGMVDVTLKQGVEKTLMERVHGVIAVRDATDHSTGAAPYISRNFAS
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: YHBQ_ECO27
Sequence: MTPWFLYLIRTADNKLYTGITTDVERRYQQHQSGKGAKALRGKGELTLAFSAPVGNRSLALRAEYRVKQLTKRQKERLVAEGAVFAELLNSLQTPEIKSD
What are the official names of this protein?
UPF0213 protein YhbQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: OTNI_CUPNH
Sequence: MPRFAANLSMMYNEHAFLDRFAAAAADGFRAVEFLFPYEHAAAELRARLDANGLTQALFNAAPGDWAAGERGLAALPGREADFRGTIGRALEYAGVIGNDRIHVMAGLIPADADRARCRATYLENLAFAANAAAAQGVTVLIEPINTRDMPGYFLNRQDDGQAICKEVGAANLKVQFDCYHCQIVEGDVAMKLKRDIAGIGHIQIAGVPERHEPDVGELNYPYLFEVMDTLGYDGWIGCEYRPRAGTSAGLGWLKPYLGR
What is the function of this protein?
Catalyzes the isomerization of 2-oxo-tetronate to 3-oxo-tetronate.
What are the official names of this protein?
2-oxo-tetronate isomerase, 2-dehydrotetronate isomerase.
What is the protein family that this protein belongs to?
Belongs to the hyi family. OtnI subfamily.
Protein: CCA_ECO24
Sequence: MKIYLVGGAVRDALLGLPVKDRDWVVVGSTPQEMLDAGYQQVGRDFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAPDVTLEDDLKRRDLTINALAQDDNGEIIDPYNGLGDLQNRLLRHVSPAFGEDPLRVLRVARFAARYAHLGFRIADETLTLMREMTHAGELEHLTPERVWKETESALTTRNPQVFFQVLRDCGALRVLFPEIDALFGVPAPARWHPEIDTGIHTLMTLSMAAMLSPQVDVRFATLCHDLGKGLTPPELWPRHHGHGPAGVKLVEQLCQRLRVPNEIRDLARLVAEFHDLIHTFPMLNPKTIVKLFDSIDAWRKPQRVEQLALTSEADVRGRTGFESADYPQGRWLREAWEVAQSVPTKAVVEAGFKGVEIREELTRRRIAAIASWKEQRCPKPD
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: CTU2_ARATH
Sequence: MACNSSGCESGCYDREKDNGSKIVDDAVSGGGNHESVCVKCKCNAPMTFGDGGFDDGRFCADCFRNNVFGKFRLAVTSHAMITPSDNVLVAFSGGSSSRVSLQFVHELQIKALKNYEASRDRSLPVFGVGVAFVDETAAFPALSTEMIDAIEWVRYTVSCLSPPAKDLHVVPVESIFGSDSLDARDRLLKLLDSVPDDTGKEDLLLHLKMLSLQKVAAENGYNRLVLGSCTSRIASHVLTATVKGRGYSLSADIQHVDARWKVPIVLPLRDCVRLEITRLCLLDGLKTVELACRSQCGINDLVSSFVALLQEENPSRECTIVRTAAKLTPFYFNKIPETDDSNVPMATQRRLKRFNLKYDGSMTTEAFCPICNGPLNRSDSSELDTFEEGQESDVLYAACCSSCRFQILPQDGSSLEQFSSFLPDHMISQVKHQKVDSQAYLREKIKDCLLLDDEEVV
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 2.
What is the protein family that this protein belongs to?
Belongs to the CTU2/NCS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_PARPJ
Sequence: MLLIPAIDLKDGQCVRLKQGDMDQATIFSEEPAAMARHWVDRGARRLHLVDLNGAFAGKPKNEDAIRAIIEEVGGEIPVQLGGGIRDLNTIERYLDDGLSYVIIGTAAVKNPGFLQDACTAFGGHIIVGLDAKDGKVATDGWSKLTGHEVADLARKFEDYGCESIIYTDIGRDGMLQGINIEATVRLARAVKIPVIASGGLSNLTDIESLCEVEDEGIEGVICGRAIYSGDLDFAAAQTLADRLRESDDA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSM6_SCLS1
Sequence: MENGALNQGEGKDPSSFLSDIIGSRVIVKLNNSLVFKGELQSVDGYMNIALEKCEEWVHGKKKTVHGDAFVRGNNVMYISADDSA
What is the function of this protein?
Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates.  Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway.  Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs.  LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6. U5 tri-snRNP, and free U6 snRNP).  It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes.  LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA (By similarity).
What are the official names of this protein?
U6 snRNA-associated Sm-like protein LSm6.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: UREE_STRT1
Sequence: MIFTKVDALVKDIDVDKYHIETVILSSDDLNKKIIRVKSDHGNEFGIRLDKGQKLQNGSAFFIDDHHVLAIGVESQDLIVISPKDMDEMGITAHILGNTHKPIEVKDAKIYLEVDPVVEQVLTQKEIAYTIEEVVLDKPLRHVNLTAHEH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PQQB_ACIBS
Sequence: MHIYILGSAAGGGCPQWNCNCPNCHGVRTGTINAKVRTQSSIAISENGVDWILLNASPDIRQQLFDFKAAQPARKLRDTGITNVILMDSQLDHTTGLLTLREGCPMNVWCTEMVYQDLTTGFPVFNMLKHWNGGLQYHQVDPKQAFIIDGFENLEFLPLIIQSAAPPYSPHRHDPHEGDNIALIIKDHKTQKQLFYAPGLGKIDDQIMQIMQDSDCVMIDGTLWTDDEMQQTGVGKKTGREMGHLYISGEGGSLSYLNQLSTPKKVLIHINNTNPILNEDSAQFAELKANGVEVAFDGMQIEL
What is the function of this protein?
May be involved in the transport of PQQ or its precursor to the periplasm.
What are the official names of this protein?
Coenzyme PQQ synthesis protein B, Pyrroloquinoline quinone biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the PqqB family.