PharMolix/UniProtQA huggingface dataset:
Protein: H17A1_CYRHA
Sequence: MTTVGVSLFRRSPEKITMKIATFLGLSFLLIASYVLICEAQHPGFQELLILEENMRDPENSKERSCAKPRENCNRMNILCCRGECVCPTFGDCFCYGD
What is the function of this protein?
Putative ion channel inhibitor.
What are the official names of this protein?
Hainantoxin-XVII, HNTX-XVII, Peptide F2-20.97.
What is the protein family that this protein belongs to?
Belongs to the hainantoxin family. 17 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EF1D_MOUSE
Sequence: MATNFLAHEKIWFDKFKYDDAERRFYEQMNGPVTSGSRQENGASVILRDIARARENIQKSLAGSSGPGASSGPGGDHSELIVRITSLEVENQNLRGVVQDLQQAISKLEARLSSLEKSSPTPRATAPQTQHVSPMRQVEPPTKKGATPAEDDEDKDIDLFGSDEEEEDKEAARLREERLRQYAEKKAKKPTLVAKSSILLDVKPWDDETDMAQLETCVRSIQLDGLVWGASKLVPVGYGIRKLQIQCVVEDDKVGTDLLEEEITKFEEHVQSVDIAAFDKI
What is the function of this protein?
Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE).
What are the official names of this protein?
Elongation factor 1-delta, EF-1-delta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
What are the subcellular locations of this protein?
[Isoform 3]: Nucleus.
Protein: DHC24_MOUSE
Sequence: MEPAVSLAVCALLFLLWVRVKGLEFVLIHQRWVFVCLFLLPLSLIFDIYYYVRAWVVFKLSSAPRLHEQRVRDIQKQVREWKEQGSKTFMCTGRPGWLTVSLRVGKYKKTHKNIMINLMDILEVDTKKQIVRVEPLVSMGQVTALLNSIGWTLPVLPELDDLTVGGLIMGTGIESSSHKYGLFQHICTAYELILADGSFVRCTPSENSDLFYAVPWSCGTLGFLVAAEIRIIPAKKYVKLRFEPVRGLEAICEKFTRESQRLENHFVEGLLYSLDEAVIMTGVMTDDVEPSKLNSIGSYYKPWFFKHVENYLKTNREGLEYIPLRHYYHRHTRSIFWELQDIIPFGNNPIFRYLFGWMVPPKISLLKLTQGETLRKLYEQHHVVQDMLVPMKCMSQALHTFQNDIHVYPIWLCPFILPSQPGLVHPKGDEAELYVDIGAYGEPRVKHFEARSCMRQLEKFVRSVHGFQMLYADCYMNREEFWEMFDGSLYHKLRKQLGCQDAFPEVYDKICKAARH
What is the function of this protein?
Catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis (PubMed:26114596).  In addition to its cholesterol-synthesizing activity, can protect cells from oxidative stress by reducing caspase 3 activity during apoptosis induced by oxidative stress.  Also protects against amyloid-beta peptide-induced apoptosis (By similarity).
What are the official names of this protein?
Delta(24)-sterol reductase, 24-dehydrocholesterol reductase, 3-beta-hydroxysterol Delta-24-reductase.
What is the protein family that this protein belongs to?
Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein.
Protein: SGMR1_TRIVU
Sequence: MQWAAGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDS
What is the function of this protein?
Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane.  Involved in the regulation of different receptors it plays a role in BDNF signaling and EGF signaling.  Also regulates ion channels like the potassium channel and could modulate neurotransmitter release.  Plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum.  Plays a role in several other cell functions including proliferation, survival and death.  Originally identified for its ability to bind various psychoactive drugs it is involved in learning processes, memory and mood alteration (By similarity).  Necessary for proper mitochondrial axonal transport in motor neurons, in particular the retrograde movement of mitochondria.  Plays a role in protecting cells against oxidative stress-induced cell death via its interaction with RNF112 (By similarity).
What are the official names of this protein?
Sigma non-opioid intracellular receptor 1, Sigma 1-type opioid receptor, Sigma1-receptor, Sigma1R.
What is the protein family that this protein belongs to?
Belongs to the ERG2 family.
What are the subcellular locations of this protein?
Nucleus inner membrane. Nucleus outer membrane. Nucleus envelope. Cytoplasmic vesicle. Endoplasmic reticulum membrane. Membrane; Single-pass membrane protein. Lipid droplet. Cell junction. Cell membrane. Cell projection, growth cone. Postsynaptic density membrane. Note=During interphase, detected at the inner and outer nuclear membrane and the endoplasmic reticulum. Detected on cytoplasmic vesicles during mitosis. Targeted to lipid droplets, cholesterol and galactosylceramide-enriched domains of the endoplasmic reticulum (By similarity). Enriched at cell-cell communication regions, growth cone and postsynaptic structures. Localization is modulated by ligand-binding. In motor neurons it is enriched at cholinergic postsynaptic densities (By similarity).
Protein: RL2_BACC0
Sequence: MGIKKYNPTTNGRRNMTTNDFAEITTDRPEKSLLAPLSKKAGRNNQGKITVRHQGGGHKRQYRIIDFKRNKDGIPGRVATIEYDPNRSANIALINYVDGEKRYILAPKNLEVGMEIMSGAEADIKIGNALPLINIPVGTVVHNIELKPGRGGQLVRSAGTSAQVLGKEGKYVLVRLTSGEVRLVLSACRATVGQVGNESHELIKIGKAGRSRWLGKRPTVRGSVMNPVDHPHGGGEGRSPIGRKSPMSPWGKPTLGFKTRKKNKASDKFIVRRRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: PAND_XYLFM
Sequence: MQLSLLKAKIHRATVSHSELNYEGSIAIDGLLLEAAGLYEFEKVHIWNVTNGARFTTYAIRAEHGSGIISVNGGAARYVQVGDLVIVAAFAQMSEDEAAVFRPNLVYVDAANAMTHTNHSIPTQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERA_BORDL
Sequence: MKSGFVSIIGRPSTGKSTLLNSICGHQISITSSTPQTTRNKIKGIFTDKRGQIIFIDTPGFHLSKKNFNIALMNNVYSAIIETELIIYVIDIQDQPGTEENEILTIIQRSKINFIVVINKIDIHKTKEKEIMTFLEEKKIQKNKIIKISAEKQINIETMKDKIYENLNEGPLYYPKEYYTDQKINLRISEIIRGVTIKKLKEELPYSIYTEIEILEDRENKFFIKANIIVAGESQKGIIVGKGGKGIKSIGEESRKIISKILEKKCNLFLQVKLRKNWNKNAKLIKNLIN
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: YPJA_BACSU
Sequence: MLILVLAINFLGTVYGYYWYLPQLLETPARFLIFVPDSPTATFFFLFVLLAFLMKRNAPLLEALALVTLVKYGLWAVAMNFLVLAVTGDLPWEGYMLIASHFAMAVQGVLYSPYFRFSFWHLAIAAVWTLHNDVIDYLFDMMPQYSMLSDYMTEIGYGTFWLSIFSIALAYFLVVSKKQTKLELM
What are the official names of this protein?
Uncharacterized protein YpjA.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KLOTB_HUMAN
Sequence: MKPGCAAGSPGNEWIFFSTDEITTRYRNTMSNGGLQRSVILSALILLRAVTGFSGDGRAIWSKNPNFTPVNESQLFLYDTFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVSSTNGSSDSYIFLEKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWDLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAPGEKGNLAAVYTVGHNLIKAHSKVWHNYNTHFRPHQKGWLSITLGSHWIEPNRSENTMDIFKCQQSMVSVLGWFANPIHGDGDYPEGMRKKLFSVLPIFSEAEKHEMRGTADFFAFSFGPNNFKPLNTMAKMGQNVSLNLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVFGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIRENGFSLKESTPDVQGQFPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLHRVEGVRLKTRPAQCTDFVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLSDIYNRSGNDTYGAAHNLLVAHALAWRLYDRQFRPSQRGAVSLSLHADWAEPANPYADSHWRAAERFLQFEIAWFAEPLFKTGDYPAAMREYIASKHRRGLSSSALPRLTEAERRLLKGTVDFCALNHFTTRFVMHEQLAGSRYDSDRDIQFLQDITRLSSPTRLAVIPWGVRKLLRWVRRNYGDMDIYITASGIDDQALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLAEEKSKPRFGFFTSDFKAKSSIQFYNKVISSRGFPFENSSSRCSQTQENTECTVCLFLVQKKPLIFLGCCFFSTLVLLLSIAIFQRQKRRKFWKAKNLQHIPLKKGKRVVS
What is the function of this protein?
Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis.  Probably inactive as a glycosidase.  Increases the ability of FGFR1 and FGFR4 to bind FGF21 (By similarity).
What are the official names of this protein?
Beta-klotho, BKL, BetaKlotho, Klotho beta-like protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family. Klotho subfamily.
Protein: BM8C_BOMMX
Sequence: MKCFAQIVVLLLVIAFSHGAVITGVCDRDAQCGSGTCCAASAFSRNVRFCVPLGNNGEECHPASHKVPYNGKRLSSLCPCNTGLTCSKSGEKFQCS
What is the function of this protein?
Potent agonist for both PKR1/PROKR1 and PKR2/PROKR2, and inducer of a potent and long-lasting hyperalgesia.  Also potentiates capsaicin-induced TRPV1 current, when tested on DRG neurons.  At subnanomolar concentrations, this protein both induces potent chemotaxis of macrophages and stimulates LPS-induced production of the pro-inflammatory cytokines IL-1 and IL-12.  In vivo, potently stimulates the contraction of the guinea-pig gastrointestinal (GI) smooth muscle (nanomolar concentration).
What are the official names of this protein?
Prokineticin Bm8-c.
What is the protein family that this protein belongs to?
Belongs to the AVIT (prokineticin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEU3_THIDA
Sequence: MKIAVLPGDGIGPEIISQAVKVLEALKSEGAKIEMETAPIGGAGYDAAGDPLPEATLKLAREADAVLLGAVGGPQYDTLDRPLRPERGLLRIRKELNLFANLRPALLYPELASASSLKPEVVSGLDLMIVRELTGDVYFGQPRGIETRNGERVGFNTMLYSESEVRRVAHVAFGIAMKRGKKLCSVEKANVLECSELWKEIMIEVAKDYPEVELSHMYVDNAAMQLIRAPKQFDTIVTGNIFGDILSDAASMLSGSIGMLPSASLDEHNKGMYEPIHGSAPDIAGKNLANPLATILSVAMMYRYTFADLATADRIENAVKQVIAKGYRTGDIWTEGTQKVSCSEMGDAVVVAL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSD_CHLTI
Sequence: APEQSKSIPRGEILSLSCAGCHGTDGKSESIIPTIYGRSAEYIESALLDFKSGARPSTVMGRHAKGYSDEEIHQIAEYFGSLSTMNN
What is the function of this protein?
Monoheme cytochrome that function as the electron transport subunit of sulfide dehydrogenase.
What are the official names of this protein?
Cytochrome subunit of sulfide dehydrogenase, FCSD, FC, Flavocytochrome c cytochrome subunit.
What are the subcellular locations of this protein?
Periplasm.
Protein: RS12_CAMJR
Sequence: MPTINQLVRKERKKVLEKSKSPALKNCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTSGFEVISYIGGEGHNLQEHSIVLVRGGRVKDLPGVKYHIVRGALDTAGVAKRTVSRSKYGAKRPKAGAAK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: NADC_HUMAN
Sequence: MDAEGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFFDAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLFAKEVAPVPKIH
What is the function of this protein?
Involved in the catabolism of quinolinic acid (QA).
What are the official names of this protein?
Nicotinate-nucleotide pyrophosphorylase [carboxylating], Quinolinate phosphoribosyltransferase [decarboxylating], QAPRTase, QPRTase.
What is the protein family that this protein belongs to?
Belongs to the NadC/ModD family.
Protein: SIL1_HUMAN
Sequence: MAPQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRTLVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEKLQQYRQVHLLPGLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGRTLASLQAEYQVLASLELQDGEDEGYFQELLGSVNSLLKELR
What is the function of this protein?
Required for protein translocation and folding in the endoplasmic reticulum (ER).  Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5.
What are the official names of this protein?
Nucleotide exchange factor SIL1, BiP-associated protein, BAP.
What is the protein family that this protein belongs to?
Belongs to the SIL1 family.
Protein: AROD_SULAC
Sequence: MIYISPKLVVALPVKELKDLNRIELLINDVDLVELRLDYLSKFDVDILDLFSKYKEKLIITLRDKDEGGVNYIDPAFKANFVRRMEREKFMYDIEARFALRYQVNVKDKIVSIHYFDNLPEFTEVKEIFDKFDEAYLRKIAVIAKRGYRELLMRVLDNYDNAVVMPMGVNGVERIAFSLLGSKLIYAHAGEETAKGQLHYKDVRRILNQLSTIMSSPST
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: ARLY_SHEPW
Sequence: MALWGGRFSQESSALFKLFNDSLPVDYRLIEQDIIGSIAWASAITQVGVLTTDECTQLHAALNELLAETSTNPELIIASGAEDIHSFVEQSLIAKVGDLGKKLHTGRSRNDQVATDLKLWCKKEGQELLELLGKLRTALIELAEREIDAVMPGYTHLQRAQPVLFGHWCLAYVEMFERDISRLQDALKRADTCPLGTGALAGTAYPMDRVKLAQSLGFASPTLNSLDTVSDRDHVVEICSDASISMMHLSRMAEDLIFFNSGEAGFIELDDEVTSGSSLMPQKKNPDALELIRGKTGRVYGSLIGILTTMKALPLAYNKDMQEDKEGLFDVMDSWAICLEMAALVLSGLQVNRERTLSAAQQGYANSTELADYLVAKGMPFREAHHVVGEAVVNAIAKQTPLEDLPLEELQSFSAIIEADVYECLTIESCLAKREALGGTSLPQVKSALAGKQVIPIALSI
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUS_MEASI
Sequence: MSIMGLKVNVSAIFMAVLLTLQTPTGQIHWGNLSKIGVVGIGSASYKVMTRSSHQSLVIKLMPNITLLNNCTRVEIAEYRRLLRTVLEPIRDALNAMTQNIRLVQSVASSRRHKRFAGVVLAGAALGVATAAQITAGIALHQSMLSSQAIDNLRASLETTNQAIEAIRQAGQEMILAVQGVQDYINNELIPSMNQLSCDLIGQKLGLKLLRYYTEILSLFGPSLRDPISAEISIQALSYALGGDINKVLEKLGYSGGDLLGILESRGIKARITHVDTESYFIVLSIAYPTLSEIKEVIVHRLEGVSYNIGSQEWYTTVPKYVATQGYLISNFDESSCTFMPEGTVCSQNALYPMSPLLQECLRGSTKSCARTLVSGSFGNRFILSQGNLIANCASILCKCYTTGTIIRQDPDKILTYIAADHCPVVEVNGVTIQVGSRRYPDAVDLHRIDLGPPISLERLDVGTNLGSAIAKLEDAKELLESSDQILRSMKGLSSTSIVYILIAVCLGGLIGIPALICCCRGRCNKKGE
What is the function of this protein?
Class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes.  Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.  This fusion is pH independent and occurs directly at the outer cell membrane.  The trimer of F1-F2 (F protein) probably interacts with H at the virion surface.  Upon HN binding to its cellular receptor, the hydrophobic fusion peptide is unmasked and interacts with the cellular membrane, inducing the fusion between cell and virion membranes.  Later in infection, F proteins expressed at the plasma membrane of infected cells could mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis (By similarity).
What are the official names of this protein?
Fusion glycoprotein F0.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses fusion glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass membrane protein.
Protein: YTHA_ECOLI
Sequence: MIKNFIFDNLIILAVPFMIKTSLKTNLIFFFLCVFVPHMAS
What are the official names of this protein?
Uncharacterized protein YthA.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HBA_PSEUR
Sequence: SLTDKDKATVKALWGKISKSADAVGADAVGRMIVVYPQTKTYFSHWPDLAPNSPHVKTHGKTVMTGIALAVSKIDDLTNGLLELSEEHAYKMRVDPANFKILSHCMLVVIATMFPKEFTPEAHVCLDKFLCAVSLALSERYR
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: Y1519_METJA
Sequence: MRNLISLIAWHDSGWNGRVCRNPKENKYCESFGYVIRKRKYEFCVNNPDANLGNSRERACSEAIVFCKGKVQEHNIRFPAIFYVDRKNRNEHEIKMIKKEIEEQLRMINGKYAILYVRENPLSENRVIVGCVKIKEIIDGSKDYIRKKQSPNRVGRGIVFDVENDVIFALPYQELLEYCKNKNKEIEEILKEFNLIFEVGDFERYFKGMSNFISDEVAVQILKKGLEIVEEFNKFREENQDFDKYLTDENIAFRPHVMKKFDEFAENIKKVIAELEGSKYKYPGLPGVLYFLGMEDAYSRYIELWKNEGEKGEEKLYNALIESLENRKENLEFGITKKVIDKFIAQKEEFREFLKNYAVYYELSAFKLEKIKEQYEKEFINLDNIIKNPYILVEDLKENDSFERIIFEELDSWERRRLGDKFNPYSPYRVRALLVEILKRHLSSGNTTISTKDLKDFFEKMDKDIVKITFDEFLRIIEEYKDIISEKVEIVKKEVKNNENKEIIELFTLKEIREYEEIIENTINYLLKSKAPNIDLNPLEIREKLRIKNENKKPAGVDNEEYEKALDMQTEAVVNLLKNRVGILTGPAGTGKTTVIKTIMELMKEVLGLNKIYILTPTGKSAMVVNEKLNNLATAKTIHRYIAEEFKDYFEGDNYFILRLDKITGNDKKEIDALIIDESSMVDIETMGRLLGTIKLDNLKYLIFVGDINQLPPVGAGKPFYDIYNYLEKVNPQSICKLEIVLRADSKKIVELSKLFLDIDKEERIKILNEMFKNKETLGDNEIYRIKENIGGIEKEIITIEVVKDGNIKKSLENAIETILKENNTEDFFDFAVFNDKLQILVPTKTKGEFGSYMINLFIKQESKFIPDKYKNKMLENWFFGDGKVADKVIQIRNNYKKWVYDTERRKWVKEHGVFNGMMGFAYTFKKWNKYQKKYENKTIIRFYYPKIEAYTDEKEMEHAYAITIHKSQGSGFENVILIIPKGLNKFVSKEMLYTAITRAKKRLYVIVEEELKNFLETNISDLARRKTNLLENFNISYLVPYIENRQIITINGEKVRSWQECVLANLFHEVGIEYIYELLSEYLKIGVLPDFKLNIKNRTILWEHYGMLENEKYRKRQKEEKEPIYKQNGFEIIKLSEINENTKLGDKVLIISTSEDLKNNSQVLEKLKTLQQIS
What are the official names of this protein?
Uncharacterized protein MJ1519.
Protein: THIM_BACC1
Sequence: MNMKEISKVVDLVRESNPLVHNITNVVVTNFTANGLLALGASPVMAYAKEEVAEMASIAGALVLNMGTLRPEEVEAMLLAGKSANVNNVPVLFDPVGAGATSYRTEVARHIPAEIELAIIRGNAAEIANVINERWEIKGVDAGAGNGNVVSIAKQAADELNTVAVITGEEDVVTDGERTIVIQNGHSILTKVTGTGCLLTSVIGAFVAVEKDYVKAAIAALTFYGVAAELAAAKTVEKGPGSFQIEFLNQLANTTSGDIEKYGKIEVI
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: AGNO_SV40
Sequence: MVLRRLSRQASVKVRRSWTESKKTAQRLFVFVLELLLQFCEGEDTVDGKRKKPERLTEKPES
What is the function of this protein?
Alters the structure of the nuclear envelope by interacting with host CBX5 and disrupting CBX5 association with LBR.  Involved in the perinuclear-nuclear localization of the capsid protein VP1 during virion assembly and maturation.  Plays an important role in the release of progeny virions from infected cells and in viral propagation, probably by acting as a viral ionic channel in the host plasma membrane.  Allows influx of extracellular calcium ions in the host cell.  May contribute to viral genome transcription and translation of viral late proteins (By similarity).
What are the official names of this protein?
Agnoprotein.
What is the protein family that this protein belongs to?
Belongs to the polyomaviruses agnoprotein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus membrane; Single-pass type II membrane protein. Host rough endoplasmic reticulum membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein. Note=Mostly perinuclear.
Protein: Y2384_BACCZ
Sequence: MNKLSTKLVVAIGIGSALYGILGLWGFSIAPNTFIKPALAILTVFGALFGPVAGLLIGLIGHTLTDTIAGWGIWWGWVISSGIIGFTMGLIQKRVGFSVKNGTYNKGDISYLAITGLIGIVIAIIFAGAFDIIVMGEPFDKIVIQVLGATIADVIVFLVLGLPITIGLAKSNKKHTHLKIEK
What are the official names of this protein?
UPF0397 protein BCE33L2384.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EUG1_YEAST
Sequence: MQVTTRFISAIVSFCLFASFTLAENSARATPGSDLLVLTEKKFKSFIESHPLVLVEFFAPWCLHSQILRPHLEEAASILKEHNVPVVQIDCEANSMVCLQQTINTYPTLKIFKNGRIFDGQVYRGVKITDEITQYMIQLYEASVIYLNSEDEIQPYLENATLPVVINRGLTGLNETYQEVALDLAEDYVFLSLLDSEDKSLSIHLPNTTEPILFDGNVDSLVGNSVALTQWLKVVILPYFTDIEPDLFPKYISSNLPLAYFFYTSEEELEDYTDLFTQLGKENRGQINFIALNSTMFPHHVRFLNMREQFPLFAIHNMINNLKYGLPQLPEEEYAKLEKPQPLDRDMIVQLVKDYREGTAKPIVKSEEIPKEQKSNVYKIVGKTHDDIVHDDDKDVLVKYYATWCIHSKRFAPIYEEIANVLASDESVRDKILIAEVDSGANDILSFPVTGYPTIALYPAGNNSKPIIFNKIRNLEDVFEFIKESGTHHIDGQAIYDKLHQAKDSEVSTEDTVHDEL
What is the function of this protein?
Probably interacts with nascent polypeptides in the endoplasmic reticulum.  It is an essential gene only in the absence of PDI.  Its native disulfide isomerase activity is very low.
What are the official names of this protein?
Protein disulfide-isomerase EUG1, PDI, Endoplasmic reticulum protein EUG1.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: YBEY_CAMJJ
Sequence: MILSDEKCDFLESIASFLGPKDVELVFVDSKEMQEINLEQRKQDKTTDVLSFPLENIDESLPLGSVVINVDLAKEKAKELGHSYEEEISLLFIHAMLHLLGFDHENDNGEMREKEKELIEYFNLPKSLIVRTLG
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2319_HALLT
Sequence: MTTVTLIGTRLADTGREFVYQGESPDCEGCPYRSQCLNLSEGTRYRVTGIRENAQTLDCAVHDAGVRAVEVEPAPVPANVLSKQAYAGGRVSLAGPCPHTECPSHGYCVPDGADFDDERVIDQVLGEPPHDVCALDRDLTLVEFRAEDG
What are the official names of this protein?
UPF0179 protein Hlac_2319.
What is the protein family that this protein belongs to?
Belongs to the UPF0179 family.