PharMolix/UniProtQA huggingface dataset:
Protein: ECCA3_MYCS2
Sequence: MGSDTLAAPPHGAPRVDRDVVSRFATCCRALGLTVNDRQRPADLTAARAGFAGLTHLAHDQCDAWIGLAAAGEVTPAVVDAVWRTVASAGVLQREIGLAAGELGFTYDTGWYLQFRATEPDDFQLAYAARLYEAGEFGEADGLVGEILARRPGWFDARWLQVAINHRAQRWSDVVRLLTPVVTLPSLDDVTSHAVRTALGISLARLGMFAPAMSYLEDPAGPIEVAAVDGALAKALTLRAQGEDDEATEVLQDLFATHPENTQVEQALLDTSFGLVTTTSARIEARSDPWDPETEPSEAEFVDPGAKDRKAHLLLEAEAELAEFIGLEEVKFQVARLKSSVAMAIRRQERGLAVAQRTNHLVFAGPPGTGKTTIARVVAKIYCGLGLLKKETVREVHRADLIGQHIGETEAKTNAIIDSALDGVLFLDEAYALVSTGAKNDFGLVAIDTLLARMENDRDRLVVIVAGYRKDLDAFLDTNEGLRSRFTRSIDFPSYTAPELVEIAVRMAEKRDSVFEKAAHDDMERLFTHLAQATTPDANGVERRSLDIAGNARFVRNLVERSEEEREYRLDHSDQEDFTDEEMMTITAGDVQRSAAPLLRGLGLSVPA
What is the function of this protein?
Part of the ESX-3 specialized secretion system, which is required for siderophore-mediated iron acquisition and for the secretion of EsxH and EsxG (PubMed:19846780, PubMed:24803520).  EccA3 exhibits ATPase activity and may provide energy for the export of ESX-3 substrates (By similarity).
What are the official names of this protein?
ESX-3 secretion system protein EccA3, ESX conserved component A3, Type VII secretion system protein EccA3, T7SS protein EccA3.
What is the protein family that this protein belongs to?
Belongs to the CbxX/CfxQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNT5_MOUSE
Sequence: MEEKYGGDARPGPGGGLGPVDVPSARLTRYILLLCLTKCLKAVGLFESYDLLKAVHIVQFIFILKLGTAFFMVLFQKPFSSGKPITKHQWIKIFKHAVAGCIISLLWFFGLTLCGPLRTLLLFEHSDIVVISLLSVLFTSSGGGPAKTRGAAFFIIAVICLLLFDNDDLMAKMAEHPEGHHDSALTHMLYTAIAFLGVADHKGGVLLLVLALCCKVGFHTASRKLSIDVGGAKRLQALSQLVSVFLLCPWVIVLSVTTESKVESWFSLIMPFTTVIFFVMILDFYMDSVCSVKMDVSKCARYGSFPIFISALLFGNFWTHPITDQLRAMNRAAHQESTEHVLSGGVVVSAVFFILSANILSSPSKRGQKGTLIGYSPEGTPLYHFMGDAFQHSSQSVPRFIKDSLKQVLEESDSRQIFYFLCLNLLFTFVELFYGVLTNSLGLISDGFHMLFDCSALVMGLFAALMSRWKATRIFSYGYGRIEILSGFINGLFLIVIAFFVFMESVARLIDPPELDTNMLTPVSVGGLIVNLIGICAFSHAHSHGHGASQGNCHSDHGHSHHAHGHGHDHGHSHGFTGGGMNANMRGVFLHVLADTLGSIGVIVSTVLIEQFGWFIADPLCSLFIAVLIFLSVIPLIKDACQVLLLRLPPDHEKELHIALEKIQKIEGLISYRDPHFWRHSASIVAGTIHIQVTSEVLEQRIVQQVTGILKDAGVNNLTIQVEKEAYFQHMSGLSTGFHDVLAMTKQMESLKYCKDGTYIM
What is the function of this protein?
Together with SLC30A6 forms a functional proton-coupled zinc ion antiporter mediating zinc entry into the lumen of organelles along the secretory pathway.  By contributing to zinc ion homeostasis within the early secretory pathway, regulates the activation and folding of enzymes like alkaline phosphatases and enzymes involved in phosphatidylinositol glycan anchor biosynthesis.  Through the transport of zinc into secretory granules of pancreatic beta-cells, plays an important role in the storage and secretion of insulin.
What are the official names of this protein?
Proton-coupled zinc antiporter SLC30A5, Solute carrier family 30 member 5, Zinc transporter 5, ZnT-5.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Note=Perimeter of granules, localizes to the brush border membrane of the enterocyte. Concentrated in early compartments of the secretory pathway such as COPII-coated vesicles (By similarity).
Protein: CH10_CAMHC
Sequence: MKFQPLGKRVLIEREEESNKTASGIIIPDNASKEKPSTGKIVEVGTECDCVKAGDKVAFAKYSGSELTLGDKKYLILNLEDVLGIIK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_DICT6
Sequence: MDLYLYNTLTKRKEKFEPLNPPYVGMYTCGPTVYNYAHIGNLRTYIFEDILKRVLIYNGYIVKHVMNITDVGHLTSDADEGEDKIEREAKKERRSAWEIAEFYTEAFKRDLKKLNILEPDIWCKATDHIQDFIDLILILERKGYTYRTSDGIYFDTSKVPDYGKLAGQDLENLLPGARVEYNPEKKNPTDFALWKFSPKDVKRQMEWDSPWGVGFPGWHIECSAMSTKYLGQPFDIHCGGIDHIPIHHTNEIAQSEAAYDKPMAKYWLHGEFLIMGEKRMGKSEGNFITLSDLEEKGYHPLSYRYFCLTAHYRSPLKFTWSALEAAQRALFRLYENMKKYPKEEAKYDEKYEEEFHKAINDDLDMPKALAITWELVKDDKLAPEVKRATLLQFDKVLGLSLDNPPEIKIEIPEEIWKLVEERELARKNKDWEKADRIREEIKNRGYIIEDTPQGPRIKKATPLTK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBI4P_YEAST
Sequence: MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGN
What is the function of this protein?
Ubiquitin exists either covalently attached to another protein, or free (unanchored).  When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains).  Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, and DNA-damage responses.  Linear polymer chains formed via attachment by the initiator Met lead to cell signaling.  Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed.  When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).
What are the official names of this protein?
Polyubiquitin.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PROA_PHOLL
Sequence: MLEQMGKAAREAAWQLAQLSTKQKNQALIRIADLLEQESAIILEANQLDMIQAREQGMSEALLDRLLLTPERLTAIAHDVRQVCGLSDPVGEVIDGSLLDSGLRLERRRVPLGVVGVIYEARPNVTIDVASLCLKTGNAVILRGGKETHNTNQATVKVIQQALEQSGLPAAAVQAIDKPDRELVIQLLKLDRYVDMLIPRGGAGLHKLCREQSTIPVITGGIGVCHTFVDESADFDKALTVITNAKVQRPSACNALETLLVHQKIAADFLPALSKYMEEQGVTLHASKSAMVFLKDGAAKVVDVTEADYRDEWLSLDMNVEIVSDMEQAIDHIRTYGTSHSDAILTQSLHNADYFVRQVDSAAVYVNASTRFTDGGQFGLGAEVAVSTQKLHSRGPMGLDALTTYKWIGYGEDLVRK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARSI_HUMAN
Sequence: MHTLTGFSLVSLLSFGYLSWDWAKPSFVADGPGEAGEQPSAAPPQPPHIIFILTDDQGYHDVGYHGSDIETPTLDRLAAKGVKLENYYIQPICTPSRSQLLTGRYQIHTGLQHSIIRPQQPNCLPLDQVTLPQKLQEAGYSTHMVGKWHLGFYRKECLPTRRGFDTFLGSLTGNVDYYTYDNCDGPGVCGFDLHEGENVAWGLSGQYSTMLYAQRASHILASHSPQRPLFLYVAFQAVHTPLQSPREYLYRYRTMGNVARRKYAAMVTCMDEAVRNITWALKRYGFYNNSVIIFSSDNGGQTFSGGSNWPLRGRKGTYWEGGVRGLGFVHSPLLKRKQRTSRALMHITDWYPTLVGLAGGTTSAADGLDGYDVWPAISEGRASPRTEILHNIDPLYNHAQHGSLEGGFGIWNTAVQAAIRVGEWKLLTGDPGYGDWIPPQTLATFPGSWWNLERMASVRQAVWLFNISADPYEREDLAGQRPDVVRTLLARLAEYNRTAIPVRYPAENPRAHPDFNGGAWGPWASDEEEEEEEGRARSFSRGRRKKKCKICKLRSFFRKLNTRLMSQRI
What is the function of this protein?
Displays arylsulfatase activity at neutral pH, when co-expressed with SUMF1; arylsulfatase activity is measured in the secretion medium of retinal cell line, but no activity is recorded when measured in cell extracts (PubMed:19262745).  Lacks arylsulfatase activity (PubMed:16500042).
What are the official names of this protein?
Arylsulfatase I, ASI.
What is the protein family that this protein belongs to?
Belongs to the sulfatase family.
What are the subcellular locations of this protein?
Secreted. Endoplasmic reticulum. Note=Localized in the intracellular granular structures.
Protein: RPOC_STAAR
Sequence: MIDVNNFHYMKIGLASPEKIRSWSFGEVKKPETINYRTLKPEKDGLFCERIFGPTKDWECSCGKYKRVRYKGMVCDRCGVEVTKSKVRRERMGHIELAAPVSHIWYFKGIPSRMGLLLDMSPRALEEVIYFASYVVVDPGPTGLEKKTLLSEAEFRDYYDKYPGQFVAKMGAEGIKDLLEEIDLDEELKLLRDELESATGQRLTRAIKRLEVVESFRNSGNKPSWMILDVLPIIPPEIRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGKRVDYSGRSVIAVGPSLKMYQCGLPKEMALELFKPFVMKELVQREIATNIKNAKSKIERMDDEVWDVLEEVIREHPVLLNRAPTLHRLGIQAFEPTLVEGRAIRLHPLVTTAYNADFDGDQMAVHVPLSKEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTLERKDAVNTGAIFNNTNEVLKAYANGFVHLHTRIGVHASSFNNPTFTEEQNKKILATSVGKIIFNEIIPDSFAYINEPTQENLERKTPNRYFIDPTTLGEGGLKEYFENEELIEPFNKKFLGNIIAEVFNRFSITDTSMMLDRMKDLGFKFSSKAGITVGVADIVVLPDKQQILDEHEKLVDRITKQFNRGLITEEERYNAVVEIWTDAKDQIQGELMQSLDKTNPIFMMSDSGARGNASNFTQLAGMRGLMAAPSGKIIELPITSSFREGLTVLEYFISTHGARKGLADTALKTADSGYLTRRLVDVAQDVIVREEDCGTDRGLLVSDIKEGTEMIEPFIERIEGRYSKETIRHPETDEVIIRPDELITPEIAKKITDAGIEQMYIRSAFTCNARHGVCEKCYGKNLATGEKVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGSDITQGLPRIQEIFEARNPKGQAVITEIEGVVEDIKLAKDRQQEIVVKGANETRSYLASGTSRIIVEIGQPVQRGEVLTEGSIEPKNYLSVAGLNATESYLLKEVQKVYRMQGVEIDDKHVEVMVRQMLRKVRIIEAGDTKLLPGSLVDIHNFTDANREAFKHRKRPATAKPVLLGITKASLETESFLSAASFQETTRVLTDAAIKGKRDDLLGLKENVIIGKLIPAGTGMRRYSDVKYEKTAKPVAEVESQTEVTE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: YLZ3_SCHPO
Sequence: MNLLQLGKLHENVLDAGCEPNRNARYLASLGYKVVGIDISERAISKAIDKTSSEKSNVNFNQRDFSRLNEFKGHFDTVIDIGCFHSILNSDHEPYTASLSHICHSDSSVFLRAFSETNKSRYRRWQGHKRYSLALKRNNVKKLSL
What is the function of this protein?
Probable methyltransferase.
What are the official names of this protein?
Uncharacterized methyltransferase C750.03c.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: MATK_SISIR
Sequence: MXXXXGYLEFDGARQQSFLYPLFFREYIYVLAYDQGLNRLNRNRSIFLENADYDKKYSSLIVKRLILRMYEQNRLIIPTKGLNKNLGHTNLFYYQMISVLFAVIVEIPFSLRLGSSFEGKKLKKSYNLQSIHSIFPFLEDKFSHFNYVLDVLIPYPIHLEILVQTLRYRVKDASSLHFFRFCLYEYCNWKNFYSKKKSILNPRFLLFLYNSHVCEYESIFFFLRKRSSHLRSTSYEVFFERILFYGKIQHFLKVFINNFPAILGLLKDPFLHYVRYHGKCILATKDTPLLMNKWKYYFVNLWQCYFSVWFQSQKVNINKLSKDNLEFLGYLSSLRLNPLVVRSQMLENSFLIDNVRIKLDSKIPISSIIGSLAKDKFCNVLGHPISKATWTDSSDSDILNRFVRICRNISHYYSGSSKKKNLYRIKYILRLCCVKTLARKHKSTVRAFLKRLGSGLLEEFLTGEDQVLSLIFQRSDYASKRLYRVRVWYLDILYLNDLVNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PB2_I80A4
Sequence: MERIKELRNLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPSLRMKWMMAMKYPITADKRITEMVPERNEQGQTLWSKMSDAGSDRVMVSPLAVTWWNRNGPVTNTVHYPKVYKTYFDKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKEELQDCKISPLMVAYMLERELVRKTRFLPVAGGTSSMYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRAAVSADPLASLLEMCHSTQIGGTRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSIKREEEVLTGNLQTLKIRVHEGYEEFTMVGKRATAILRKATRRLVQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEHIDSVMGMVGVLPDMTPSTEMSMRGIRVSKMGVDEYSSTERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTERLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQNPTMLYNKMEFEPFQSLVPKAIRGQYSGFVRTLFQQMRDVLGTFDTTQIIKLLPFAAAPPKQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKTTKRLTILGKDAGTLIEDPDESTSGVESAVLRGFLILGKEDRRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.  In addition, participates in the inhibition of type I interferon induction through interaction with and inhibition of the host mitochondrial antiviral signaling protein MAVS.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host mitochondrion.
Protein: SYP72_ARATH
Sequence: MPVIDIIFRVDEICKKYDKYDIDKHREIGASGDDAFSRLFTSIDSDIEAVLRKAELASTEKNRAAAVAMNAEVRRTKARLAEDVVKLQKLAVKKIKGLTREERESRCDLVIALADRLQAIPDGNEHGAKQANSDWGGASAPNKNIKFDMSEEDMDDGFFQQSEESSQFRQEYEMRRKKQDEGLDIISEGLDALKNLARDMNEELDKQVPLMEEMETKVDGATSDLKNTNVRLKKQLVQMRSSRNFCIDIILLCVILGIVSYIYNALN
What is the function of this protein?
Vesicle trafficking protein that functions in the secretory pathway.
What are the official names of this protein?
Syntaxin-72, AtSYP72.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type IV membrane protein.
Protein: NU4LC_ACOAM
Sequence: MMLEYVLFLSAYLFSIGIYGLITSRNMVRALMCLELILNAVNINLVTFSDLFDSRQLKGDIFSIFVIAIAAAEAAIGPAIVSSIYRNRKSIRINQSNLLNK
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PSD_ECOL5
Sequence: MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKYYKVDMKEAQKPDTASYRTFNEFFVRPLRDEVRPIDTDPNVLVMPADGVISQLGKIEEDKILQAKGHNYSLEALLAGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYVPGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTITPPREGIIKRWTWPAGENDGSVALLKGQEMGRFKLGSTVINLFAPGKVNLVEQLESLSVTKIGQPLAVSTETFVTPDAEPAPLPAEEIEAEHDASPLVDDKKDQV
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MMP23_BOVIN
Sequence: MGRGACVPSAASGAGDRARQLGAVLGALCLFPALVLLAWPGTPANGAGARVAQGDAAPQTSGVLASGSLGPPHPPVPRRRRYTLTPARLRWEHFNLTYKILSFPRNLLSPSETRRGLAAAFRMWSDVSPFSFREVAPEQPSDLRIGFYPVNHTDCLVSPLHHCFDGPTGELAHAFFPPHGGIHFDDSEYWVLGRTRYSWKKGVWLTDLVHVAAHEIGHALGLMHSQHGRALMHLNATLRGWKALSQDELWGLHRLYGCLDRLFVCASWARRGFCDTRRRLMKRLCPSSCDFCYEFPFPTVAATPPPPRTKTKLVPEGRNVTFRCGQKILHKKGKVYWYKDQEPLEFSYPGYLALGEAHLSIIANAINEGTYTCVVRRRQRVLSTYSWRIRVRS
What is the function of this protein?
Protease.  May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity).
What are the official names of this protein?
Matrix metalloproteinase-23, MMP-23, Matrix metallopeptidase 23B.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane; Single-pass type II membrane protein. Note=A secreted form produced by proteolytic cleavage may also exist.
Protein: CMTAD_PSEPU
Sequence: MTNIIETVDLTDLVGLCATDDVAEGEILRVKLPSGHALAIYCVNGEFFATDDICSHGEASLSEDGSLDGYEVECSWHFGRFDIRTGHACAMPCEHPLRSWPVTVEGGQIFVDVGAHPV
What is the function of this protein?
Component of the p-cumate 2,3-dioxygenase multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into p-cumate to form cis-2,3-dihydroxy-2,3-dihydro-p-cumate.  Functions as an intermediate electron transfer protein via a specific interaction with iron sulfur protein components (ISP)(CmtAb and CmtAc).
What are the official names of this protein?
p-cumate 2,3-dioxygenase system, ferredoxin component.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin component family.
Protein: LPXD_BACFN
Sequence: MEFSAKQIAAFIQGEIIGDENATVHTFAKIEEGIPGAISFLSNPKYTPYIYETKASIVLVNKDFTPEQEVKATLIKVDNAYESLAKLLNLYEMSKPKRTGIDERAYVAETAKIGKDVYIAPFACIGDHAEVGDNTVIHPHATVGGGAKIGSNCILYANSTVYHDCRVGNNCILHAGCVIGADGFGFAPTPQGYEKIPQIGIVILEDNVEVGANTCIDRATMGATVIHSGVKLDNLVQIAHNDEIGSHTVMAAQVGIAGSTKVGEWCMFGGQVGIAGHLKIGNQVNLGAQSGVPGNIKSGSQLIGTPPMELKQFFKASIVQKSLPEMQIELRNLRKEIEELKQQLNK
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: LHX9_DANRE
Sequence: MEVVGCKAKESSCTLRPAAMLFHGISGDHIQGIMEEMERRSKSESRLAKTVQMNGRETTMPSMSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCTTCNKTLTTGDHFGMKDNLVYCRVHFETLIQGEYHPQLNYAELAAKGGGLALPYFNGTGTVQKGRPRKRKSPAMGIDIGSYSSGCNENDADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNVLRQENGGVDKADGTSLPPPSSDSGALTPPSTATTLTDLTNPSITVVTSVTSSLDSHESGSPPQTTLTNLF
What is the function of this protein?
May be involved in gonadal development.
What are the official names of this protein?
LIM/homeobox protein Lhx9, LIM homeobox protein 9.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRPC_ECOLI
Sequence: MMQTVLAKIVADKAIWVEARKQQQPLASFQNEVQPSTRHFYDALQGARTAFILECKKASPSKGVIRDDFDPARIAAIYKHYASAISVLTDEKYFQGSFNFLPIVSQIAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDDQYRQLAAVAHSLEMGVLTEVSNEEEQERAIALGAKVVGINNRDLRDLSIDLNRTRELAPKLGHNVTVISESGINTYAQVRELSHFANGFLIGSALMAHDDLHAAVRRVLLGENKVCGLTRGQDAKAAYDAGAIYGGLIFVATSPRCVNVEQAQEVMAAAPLQYVGVFRNHDIADVVDKAKVLSLAAVQLHGNEEQLYIDTLREALPAHVAIWKALSVGETLPAREFQHVDKYVLDNGQGGSGQRFDWSLLNGQSLGNVLLAGGLGADNCVEAAQTGCAGLDFNSAVESQPGIKDARLLASVFQTLRAY
What is the function of this protein?
Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway.  The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
What are the official names of this protein?
Tryptophan biosynthesis protein TrpCF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the TrpF family.
Protein: RL18E_METMA
Sequence: MGKKSLVKLTRKTNPRIVSLILTLKDRANVDSAPIWKDIAKRLEAPSRNYAAVNISKINRHTAENDVLLVPGKVLGAGLLDHPVTVAAVTFSESAVEKITEAGGKCLSVEEIMEANPKGSGIRIFR
What are the official names of this protein?
50S ribosomal protein L18e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL18 family.
Protein: COQ42_TRYCC
Sequence: MLKSGFYLLGGVVGAASSLPAFLAATTRSIWDPVNAGDVAAVGEITALTALEHMKQSMMSDRTGRMILRTQPRVTDETLEFASRQPPGTFGHRYAQFMKFNRFTPNGRTPVAHVADPTLAYVMQRQRETHDFLHTCIGCGRTVEEEIIVKLLEWRHTGLPIGLLAVIGSLPWLSRQQLRNMELYFEWAEVNAPNQRHGEVYIPYITNVWWESYLDKPYEQLLADTGITPIDVFLQQKKGKAALANGEAIDGK
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ4 homolog 2, mitochondrial, Coenzyme Q biosynthesis protein 4 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: MIAA_CUPPJ
Sequence: MSALPSSEHPPVVCLLGPTASGKTAAALALAQQAPVEIISLDSALVYREMDIGTAKPTREELASVPHHLIDIIDPTDSYSAAQFVTDAERLIAEIRSRGHQPLIVGGTMLYYKALTQGLNDLPQADPAVRAKLDELAAERGWPALHAMLAEVDPVTAARLAPNDAQRIQRALEIHRLSGQPMSELLARQADGRTFTGAADQRYRVIALEPSDRAVLHARIAARYDAMLAGGFIEEVERLRRRGDLHPGLPSIRCVGYRQVWEYLDGDTDYATMRERGIVATRQLCKRQITWLRSTPERLSVDCVAPDYVQQVARLAGM
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: SYC_NITSB
Sequence: MVIYDSSKKEYCSLEPLKNRHIKVYVCGPTVYDDAHLGHARSAIAFDLLRRTLNALGYKTTFMKNFTDIDDKIIKKMNETGKSLQEITSYYIQRYLEDMEALGVQRADIEPKATQNLDAMIDMIERLLQKECAYQTPNGDIYFDTSKDEKYCTLSHKCDEESMSRIEPNPDKKNPADFALWKRCKGEGDVCFDSPFGKGRPGWHIECSAMIDKHLAYHDTPFQIDIHAGGADLLFPHHENEAAQTRCACNQELAKYWMHNGFVTISGEKMSKSLGNSFFIKDALKVYDGEILRFYLLSTHYRSDLNFNEEDLLASKKRLDKLYRLKKRVYGVQASTPQKEFVDELLQALSQDLNISKTLAAIDQFIAYANEHLDNNPKDKAFKKQIVANIEYISKLLGIGHKDAYSYFHLGISEEEKQKIEELIEKRTTAKKEKNFQLADSIREELRSMGIAIMDTPQGTLWEKI
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.