PharMolix/UniProtQA huggingface dataset:
Protein: LSRK_SALTI
Sequence: MARLCTHTESGHYLMALDAGTGSVRAVIFDLQGKQIAVGQAEWQHLAVPDVPGSMEFDLAKNWQLACQCIRQALQKAAIPATAIAAVSACSMREGIVIYDSNGEPIWACANVDARAAHEVSELKELHDNTFEEEVYRCSGQTLALSAIPRLLWLAHHRPDIYHRASTVTMISDWMAFMLSGELAVDPSNAGTTGLLDLVTRNWKRSLLQMAGLRSDILSPVKETGTLLGHISQKAAEQCDLQAGTPVIVGGGDVQLGCLGLGVVRPAQTAVLGGTFWQQVVNLPAPVTDPNMNVRINPHVIPGMVQTESISFFTGLTMRWFRDAFCAEEKLIAERLGIDAYSLLEDMASRVPPGAHGVMPIFSDVMRFKRWYHAAPSFINLSIDPEKCNKATLFRALEENAAIVSACNLQQIAAFSGVQADSLVFAGGGSKGKLWSQILADVTGLTVHVPVVKEATALGCAIAAGVGVGIWPSLAETGEKLVRWDREHKPNPENFAVYQQAREKWQAVYQDQRALVDGGLTTSLWKAPGL
What is the function of this protein?
Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon.  Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.
What are the official names of this protein?
Autoinducer-2 kinase, AI-2 kinase.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSSA_DROSI
Sequence: MSGGLDILSLKEDDITKMLVATTHLGSENVNFQMEQYVYKRRADGVNILNLGKTWEKLQLAARAIVAIDNPSDIFVISSRPIGQRAVLKFAKYTDTTPIAGRFTPGAFTNQIQPAFREPRLLVVTDPNTDHQPIMEASYVNIPVIAFTNTDSPLRYIDIAIPCNNKSAHSIGLMWWLLAREVLRLRGTISRSVEWPVVVDLFFYRDPEEAEKEEAAAKELLPPPKIEEAVDHPVEETTNWADEVAAETVGGVEDWNEDTVKTSWGSDGQF
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.  Required during oogenesis and imaginal development.
What are the official names of this protein?
40S ribosomal protein SA, Protein stubarista.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=May associate with nascent RNP complexes within the nucleus.
Protein: DXS_CAMJD
Sequence: MSKKFAHTQEELEKLSLKELENLAASMREKIIQVVSKNGGHLSSNLGAVELSIAMHLVFDAKKDPFIFDVSHQSYTHKLLSGKEEIFDTLRQINGLSGYTKPSEGDYFVAGHSSTSISLAVGACKAIALKGEKRIPVALIGDGALSAGMVYEALNELGDSKFPCVILLNDNEMSISKPIGAISKYLSQAMATQFYQSFKKRIAKMLDILPNSATYMAKRFEESFKLITPGLLFEELGLEYIGPIDGHNLGEIISALKQAKAIQKPCVIHAQTVKGKGYALAEGKHAKWHGVGAFDIDSGESVKKNDAKKSATEIFSKNLLDLASKYENIVGVTAAMPSGTGLDKLIEKYPNRFWDVAIAEQHAVTSMAAMAKEGFKPFIAIYSTFLQRAYDQVIHDCAIMNLNVVFAMDRAGIVGEDGETHQGVFDLSFLAPLPNFTLLAPRDEQMMHNIMEYAYLHQGPIAFRYPRGSFILDEEFNPCEIKFGKAQWLVKNSSEIAFLGYGQGVAKAWQVLRALQEMNNNANLIDLIFAKPLDEELLCELAKKSKIWFIFSENVKIGGIESLINNFLQKYDLHVKVISFEYEDKFIEHGKTSEVEKNLEKDINSLLTKVLKFHH
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: Y013_MYCPN
Sequence: MPKVISQKEFNILSRTKERVNFQIVYTKQRNGLHKAAKEYFFKDKDFTIIEDTPDTPDQPDGPCITKGPKEPGGPEEPNGPDKPEDPKDPDTPDVSEGPKEQGGQKDPGGPDDPSEGKQKVSKPDKYVTHRELDEKLKDFATKADFKRVEDKVDVLFELQKTQGEQIKVQGEQIKAQGKQIEQLTETVKVQGEQIRAQGEQIKAQSEEIKEIKVEQKAQGEQIKELQVEQKAQGKTLQLILKTLEKMNERLEKLESK
What are the official names of this protein?
UPF0134 protein MPN_013.
What is the protein family that this protein belongs to?
Belongs to the UPF0134 family.
Protein: CLCA_YERPB
Sequence: MTHSTQQLSPEGVAEGKRGRLIRELVNRDKTPLIILIMAAVVGVVTGLLGVAFDRGVDWVQQQRLLALANVADSALLVWPLAFIMSALLAMMGYFLVSRFAPEAGGSGIPEIEGAMEEMRPVRWWRVIPVKFIGGLGTLGAGMVLGREGPMVQMGGNSGRMIVDIFRLRSPEARHSLLATGAAAGLSAAFNAPLAGILFVIEEMRSQFRYSLVSIKAVFIGVITSTIVYRYFNGERAIIEVGKLSDAPLNTLWLYLLLGIIFGAVGVIFNALIFRTQDMFVRFHGGDWRKLVLIGGLLGGMCGLLALLHGNAVGGGFALIPIAAAGNFSIGMLLFIFIARVITTLLCFGSGAPGGIFAPMLALGTILGTAFGLSCAHFFPQYGIEAGTFAIAGMGALFAASVRAPLTGIVLVLEMTDNYQLILPMIVTCLGATLIAQFMGGKPLYSAILARTLAKQEQARATVIAQEPAVENTPQTGR
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges two chloride ions for 1 proton.  Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
H(+)/Cl(-) exchange transporter ClcA.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MAPK1_PNECA
Sequence: MDSKHSVFNVMGQEFVLQKGYEVIKGLGKGSYGVVCSAKNIEVEDNNKVAIKKITNIFSKKMLAKRALREIMLLQHFRNHKNITTLYDMDIVDPSKFNELYLYEELMQANLNSIIRSDQPLTDAHFQSFIYQILCGLKYIHSANVLHRDLKPSNLLINADCKLKICDFGLSRGISVNQGQGTEYMTEYVTTRWYRAPEVMLSFQSYSKAIDLWSVGCILAELLGRKPFFKGSNYVDQLNQIFCILGTPNENIISKIKSASAQSYIRSLPTLPKMPYSKIFPYANPDALDLLNCLLTFDPYDRISCEEALEHPYLIIWHDPNKEPVCSEQFDFGFEAIDSIEEIRQMIINEVSRFKGLTGNQKLYHSISNT
What is the function of this protein?
Serine-threonine protein kinase which may be involved in maintenance of cell integrity.  Functionally complements SLT2 null mutant in S. cerevisiae.
What are the official names of this protein?
Mitogen-activated protein kinase 1, MAP kinase Mkp1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Protein: CLAP2_HUMAN
Sequence: MAMGDDKSFDDEESVDGNRPSSAASAFKVPAPKTSGNPANSARKPGSAGGPKVGGASKEGGAGAVDEDDFIKAFTDVPSIQIYSSRELEETLNKIREILSDDKHDWDQRANALKKIRSLLVAGAAQYDCFFQHLRLLDGALKLSAKDLRSQVVREACITVAHLSTVLGNKFDHGAEAIVPTLFNLVPNSAKVMATSGCAAIRFIIRHTHVPRLIPLITSNCTSKSVPVRRRSFEFLDLLLQEWQTHSLERHAAVLVETIKKGIHDADAEARVEARKTYMGLRNHFPGEAETLYNSLEPSYQKSLQTYLKSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSLQRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGRVRAKLSAPLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRVLTTTALSTVSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASRESSRDTSPVRSFQPLASRHHSRSTGALYAPEVYGASGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYESYGMHSDDDANSDASSACSERSYSSRNGSIPTYMRQTEDVAEVLNRCASSNWSERKEGLLGLQNLLKNQRTLSRVELKRLCEIFTRMFADPHGKRVFSMFLETLVDFIQVHKDDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRESFPNDLQFNILMRFTVDQTQTPSLKVKVAILKYIETLAKQMDPGDFINSSETRLAVSRVITWTTEPKSSDVRKAAQSVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLRNTGNGTQSSMGSPLTRPTPRSPANWSSPLTSPTNTSQNTLSPSAFDYDTENMNSEDIYSSLRGVTEAIQNFSFRSQEDMNEPLKRDSKKDDGDSMCGGPGMSDPRAGGDATDSSQTALDNKASLLHSMPTHSSPRSRDYNPYNYSDSISPFNKSALKEAMFDDDADQFPDDLSLDHSDLVAELLKELSNHNERVEERKIALYELMKLTQEESFSVWDEHFKTILLLLLETLGDKEPTIRALALKVLREILRHQPARFKNYAELTVMKTLEAHKDPHKEVVRSAEEAASVLATSISPEQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETLNLLLPEIMPGLIQGYDNSESSVRKACVFCLVAVHAVIGDELKPHLSQLTGSKMKLLNLYIKRAQTGSGGADPTTDVSGQS
What is the function of this protein?
Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules (PubMed:26003921).  Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN).  Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell.  May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2 (PubMed:16824950).  This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling.  Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle (PubMed:16866869, PubMed:16914514).  Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.
What are the official names of this protein?
CLIP-associating protein 2, Cytoplasmic linker-associated protein 2, Protein Orbit homolog 2, hOrbit2.
What is the protein family that this protein belongs to?
Belongs to the CLASP family.
Protein: SYPM_YEAST
Sequence: MLKYRTLSRSCHIFHPKSLSNNTLKSETTQELLQTVGFVRRSQVGLFQWLPLGLRSLNKVSNAIRNRMDSDGGAIEVSLSAISSKALWQATDRWNNSELFKLKDSKGKQYCLTATCEEDITDLMKNYIASYKDMPITIYQMTRKYRDEIRPRGGILRGREFLMKDAYSFASNEEDAFASFQKLDDTYNKIFKDLKIPFVSAWADSGDIGGEFSKEFHLIHESGEDTLMSCKHCGDISTLDMSQSYPEKDGQYSGDVDCKYALTKDHSTLICFYYPKDRQLNWNLALNAMDKDIDLTLRNKPNDHVLQVYEKDNEDIMFSKILRVMDCRLNSKSNFPDFPLKKYLKNNFGQISDVSIVDAQENEICGKCEEGRLEPLKSIEVGHIFLLGNKYSKPLNVKFVDKENKNETFVHMGCYGIGVSRLVGAIAELGRDSNGFRWPAIMAPYKVSICTGPNNPENSQRLQDVKSELLNDPTMQNLQNDILDQFNEKLGIGARIKLSHAMGIPLCVIVGSKSWPNVEIEVRGIRWGEKDLWRKQFEKRCSELQWKCTKNEHGIEKHTVPIQHLAEVIGVLLKDM
What are the official names of this protein?
Probable proline--tRNA ligase, mitochondrial, Altered inheritance rate of mitochondria protein 10, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y570_MYCGA
Sequence: MVLGLALGLSIPLCLIVGAFVGYFVSMKVFKRQMRKNPPITEAQIRSLYAQMGRKPSEAQVKQMMRAYTKETK
What are the official names of this protein?
UPF0154 protein MYCGA5700.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS15_GLOC7
Sequence: MALTQTRKQEIINQYQAHGTDTGSADLQVALLTERINQLTTHLQANPKDHASRRGLLQLIGRRRGLLSYIQKKDFQRYQDLIGRLGIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: DXR_BACC7
Sequence: MKNISLLGASGSIGTQTLDVLRSHPDQFRLVAFSVGKNIDYAVKVIQEFSPQIVSVQREEDVLKLQAVSGNTKIVYGSEGLLEVALHPDAEIVVNAVVGSVGLLPTLRAIEAKKTIGIANKETLVTAGHLVMEAARKHNVSLLPVDSEHSAIFQCLNGENEKRISRLIITASGGSFRDKTRDELHHVTVEDALRHPNWSMGSKITIDSATMMNKGLEVIEAHWLFGIPYEQIDVVLHKESIIHSMVEFEDRSVMAQLGSPDMRVPIQYALTYPDRLPLSDTKQLNLWEMGTLHFEKMNQERFRCLRFAYEAGKTGGSMPAVMNAANEVAVEAFLQKRIGFLTVEDLIEKAMNHHNVIARPSLEEILEIDAATRRFVMEQI
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: GATB_OENOB
Sequence: MSSFETTIGLEVHVELKTKSKAFSLSPVNFGDPANENTNVIDWGYPGVLPSANKGALESGMMAALALNAQITRDVHWDRKNYFYPDNPKSYQVTQQQTPIGHDGYVEIKKEDGTSKRIGIKELHVEEDAGKNSHSGKGYSLVDLNRQGTPLVEIVSQPNISSPDEAYLYLEKLRQLIQFTGISDVKMQEGSMRVDINISVRPIGAEKYGTKVEIKNVNSFQYAKNALAYEEQRQRDELMAGHIIGQETRRFDEPTKSTILMRVKEGADDYRYFPEPDLPVIHVSDEWIKAVKSSLPETADDRIARYINKFALSKKEAAVLTQTLEMANFYDQVVDDGADPKRTANYLIGDVNAYLNETQLDLQDTKLTPGHLSGMIKLIDNGTISTKQAKKVFTAITDGEEPKAYVEKNGLVQLSDPNKLTPIINQILDDNQQSIDDFKGGKDRTIGYLTGQVMKKTHGNANPKIVHEILLAELKKR
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: RS7_CAMLR
Sequence: MRRRKAPVREVLPDPIYGNKVITKFINSLMYDGKKSTATTIMYGALEAIDKKGGEKKGIEIFNDAIENIKPLLEVKSRRVGGATYQVPVEVRPARQQALAIRWIISFARKRSERTMIEKLAAELLDAANSKGASFKKKEDTYKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: CYPT1_MOUSE
Sequence: MAQMAKKVHWSSAAAGAAAAAKISKLEKTTKRFKLIKKRNPSSKLPKRSSHSLLCSLSRSCCCCRCRCCCYCRCCRCCCSRSRRFRSRTTLKFFQITEKGEQSLQRRIRRQLTRSQLELIEPEPTMALEPSEITVAFFSHKNANVSDPEEVPPCLDSDPFPNGDLASS
What are the official names of this protein?
Cysteine-rich perinuclear theca protein 1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, perinuclear theca. Note=Found in the postacrosomal region of the perinuclear theca.
Protein: RPOZ_PSYA2
Sequence: MARVTIEDCLDNVDNRFELVLVASKRARQLAKGIAEPLVDVDNDKPTVLALREIAAGKITRDILNQPEHNFATSSLDLALSGDHSF
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: KCY_CHLT3
Sequence: MPEATLTKKIIIAIDGPAASGKSTTAKQLAQKLSYTYIDTGAMYRAVTLKVLRDAFFEKIFSDELFLKKLLSETEVILKGEKVFLDGEEVTKDIRTNEVSSKVSKVSSLPLVREKLVEYQRNMGKARGVVMDGRDIGTIVFPDAELKVFMIADAKERAKRRYAELKAKSPSGDPGVTLETLEQEILQRDEDDRTRAIAPLRKPDDARELDTSKMTIEEQVAAIYELATDVISQLK
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PATR_MYCTU
Sequence: MTARLRPELAGLPVYVPGKTVPGAIKLASNETVFGPLPSVRAAIDRATDTVNRYPDNGCVQLKAALARHLGPDFAPEHVAVGCGSVSLCQQLVQVTASVGDEVVFGWRSFELYPPQVRVAGAIPIQVPLTDHTFDLYAMLATVTDRTRLIFVCNPNNPTSTVVGPDALARFVEAVPAHILIAIDEAYVEYIRDGMRPDSLGLVRAHNNVVVLRTFSKAYGLAGLRIGYAIGHPDVITALDKVYVPFTVSSIGQAAAIASLDAADELLARTDTVVAERARVSAELRAAGFTLPPSQANFVWLPLGSRTQDFVEQAADARIVVRPYGTDGVRVTVAAPEENDAFLRFARRWRSDQ
What is the function of this protein?
May catalyze the transamination reaction in phenylalanine biosynthesis.
What are the official names of this protein?
Putative phenylalanine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Protein: GLGC_ECO7I
Sequence: MVSLEKNDHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDKNSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: ZNUC_BUCAP
Sequence: MLELITLKNIHVSFSGRSILSNISFSLLSNRIITLIGPNGAGKSTLIRVILGLIQPNLGNIIRSPKISVGYVPQKLYFNNLLPITVEKFMKLSKRKKNINILKILKRVKAQSLQYSRLQNLSGGEMQRILLARALLNNPNLLVLDEPTQGVDVMGQLDLYELINQIRSEMQCSILIVSHDLNFVMAKTNYVICLNKHICCSGTPQTVFKNLEFISIFGLKHIRELAIYQHNHDHVHQY
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TRUA_BORBR
Sequence: MSRIALGLAYDGSAWQGWQTQPHGVTVQDQVEAALASFAGGGGPVATVCAGRTDTGVHAAMQVIHLDTDLQRRDESWVRGVNAFLPPSIVVQWARPVSEAFHARFSARSRTYVYLLWRGRVRPALWAGRAGWAFQPLDVPAMRAAARTLLGEHDFSSFRSSQCQARHPVRTLHRLDIDERGAFLVFTLRANAFLHHMVRNLIGALLQVGQGRESVAWMDALLRARDRRLGAPTFMPDGLYLSAIEYPAEFGFDELDGGTMLLSPFTGALG
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RLMN_GLOVI
Sequence: MTTPLLGQSAEELRIWVESQGQPAYRAQQLHRWLYQRGVRSLMEITDWPKAWREQVHSVPVGRSQVVRQSAAADGTIKYLLAGADGETVETVGIPAAERLTVCVSSQVGCPMACRFCATGQSGFARNLGVHEIVDQVLTVQEGFGRRVSHVVFMGMGEPLLNLGAVVQALRVLNGDIGIGQRQITVSTVGVPGQIRRLGTYKLQITLAVSLHAPNQDLRLKLIPTAQHYPIEELLEDCRDYVETTNRRVSFEYTLLAGINDEPHHARELAAILRGFQSHVNLIPYNPIEGVEYERPGEARVRAFERELVRHKIAASVRHTRGLEEAAACGQLRRRSLSGEAQSASTRA
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR4_PASMU
Sequence: MLQIFRGSPALSEFRLNQLAVRFQKANLPVSACYAEYIHFADLSDRLTEEETAKLDQLLHYGPTLAGHDPVGHCFIVIPRIGTISSWSSKATDIAHNCGLNKVNRLERGLAFYFEFDRTLSSEEQQRLVSHIHDRMLEGIIHTPEEAKVLFDQQAPKPFTTVDILSGGRQALENANVELGLALAEDEIDYLVENFTALGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGEKQEKSLFKMIKNTFEKTPDHVLSAYKDNAAVMEGSKVGRFFPDQDGQYRYHNEDAHILMKVETHNHPTAISPFPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLVIPGFEQPWENPVSKPNRIASALDIMIEGPLGGAAFNNEFGRPALLGYFRTYEEKVNSFAGEEVRGYHKPIMLAGGIGNIRAEHVQKGEIPVGAKLIVLGGPAMNIGLGGGAASSMASGKSKEDLDFASVQRDNPEMERRCQEVIDRCWQLGEDNPILFIHDVGAGGLSNAMPELVHDGGRGGKFELRKILSDERGMSPLEIWCNESQERYVLAVAPEKLELFTALCERERAPFAVIGEATEQEHLTLHDDHFDNNPIDLPMNVLLGKTPKMTRDVKSKTVEGSALDHSQIDLKEAFHRVLRLPVVAEKTFLITIGDRSVTGMVARDQMVGPWQIPVADCAVTTASLDSYHGEAMSMGERAPVALLDFAASARLAVAESITNIAATNIGDIKRIKLSANWMSAAGHEGEDAGLYQAVKAVGEELCPQLGLTIPVGKDSMSMKTTWHENGEQKTVTAPLSLVISAFARVEDVRKTVTPQLRTDKGHSRLLLIDLGEGKNRLGATALAQVYKQLGDKPADVVNVESLKNFFNAMQALVAEQKLLAYHDRSDGGLIATLAEMAFAGNCGLSIHISALGDNDLAVLFNEELGAVIQVRESDLSYVRDVLSQHGLIHLTKELGEVTTEDRIEISRGTKLLFSQKRSELRGIWAELTHQMQRLRDNPECADQEFAAKKDPENKGFSAHLTYDINEDIAAPYIATGKKPRIAILREQGVNSHYEMAAAFDRAGFEAIDVHMSDLHNARYRLKDFNALVACGGFSYGDVLGAGGGWAKSILFNPMLRDQFSEFFANPNTLTLGVCNGCQMVSNLAEIIPGTDAWPRFVRNKSERFEARAALVRINETNSLWFQGMAGSHMPIAVSHGEGRVEFKHDQQLQMLKDQNLIVAQYIDNNLNPTEIYPANPNGSVEGITALSNQDGRVAIMMPHPERVFRTVSNSWHPEDWSEDGAWMRLFRNARVVLE
What is the function of this protein?
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase, FGAM synthase, FGAMS, Formylglycinamide ribonucleotide amidotransferase, FGAR amidotransferase, FGAR-AT.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UL13_SUHVN
Sequence: MAAGGGGGGVSRAALARPPIHRGTSAPGGAIAAAGGDGDGDEASRLLGRAQPREAPYLIPRPDGDLAVPDDLQYATLDLTGDPVAVGAGSYGSVLVYGSVAVKTLRAGFGHEAVMTLLAAEEARSAGVRGVVRLMGLSAPLRQLMFPAYEMDMDAYRRSLTARPGHVVHALGRVFTELGRALVFLNGRGLSHLDVKGGNIFVRTCGNMVVTAVIGDFSLMALNSRSALADPRFRLARRKALKITSLARSPPTGVLLGHARDRPTRVLMDFINGRPPPPGPLPYEVGLAIDLCALGHVLLDVALGLRPQRGQALTREYAVEVLARRCVLFAALLPPGSGPSAEALAGDILEEELAAGFREGVASSRPGNQPPRTVAPLLELVARFCGEDGGARFAELAA
What is the function of this protein?
Multifunctional serine/threonine kinase that plays a role in several processes including egress of virus particles from the nucleus, modulation of the actin cytoskeleton and regulation of viral and cellular gene expression.  Regulates the nuclear localization of viral envelopment factors UL34 and UL31, by phosphorylating the US3 kinase, indicating a role in nuclear egress.  Disrupts host nuclear lamins, including LMNA and LMNB1.  Phosphorylates the viral Fc receptor composed of glycoproteins E (gE) and I (gI).  Phosphorylation of glycoprotein E (gE) by UL13 alters its subcellular localization, from the host early endosome to the plasma membrane.  Participates in the transcriptional regulation of cellular and viral mRNAs mainly by phosphorylating the viral transcriptional regulator ICP22 (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase UL13.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus.
Protein: RL2_METS3
Sequence: MGKRLIIQRRGRGTPAHRVASHRFKDKIRYRSYDALEKEGSIKGIVTDIVHDPARTAPIAEVKFENGEKKFILAPESIQIDDEIECGISAPIKFGNTLPLAEIPEGTPIYDIENTPGDGGRFVRSSGTYASLITHDANQSVVELPSGELKYLNPRCRASIGVVAGGGRKEKPFLKAGNRWHAYKAKGKKFMTVRGVAMNAVDHPHGGGNRQHPGRPTTVSRHAPPGRKVGSIAAKRTGLKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: FOLD_NEIMA
Sequence: MSAQLINGKEVSQKRLQAVAEAVAQRQQDNLHMPCLAVVLVGGDPASAVYVRNKKTACQKCGIKSLSYELPESTSQEELLALVDRLNADSEVDGILVQLPLPKHLDSQAVLERISPDKDVDGFHPYNVGRLAVKMPLMRPCTPKGVMTLLEAYGIDPKGKKAVVVGASNIVGRPQALELLLARATVTVCHSATENLTDEVAGADILVVGVGIPNFVKGEWIKPGAVVIDVGINRLDDGSLCGDVEFETAKERAAMITPVPGGVGPMTIATLMENTLHAASLHDA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.