PharMolix/UniProtQA huggingface dataset:
Protein: MOKC_MONPI
Sequence: MTVPTDTVSRRLQSLAWSDIKQHAPWLPSSRTLVSGFLCLILLQILYSRGRKSDLRVYNPKKWWELTTMRAKREFDANAPAWIEAWFSKNDQPLRFIVDSGYCTILPSSMADEFRKMKELCMYKFLGTDFHSHLPGFDGFKEVTRDAHLITKVVMNQFQTQAAKYTKPLADEASATIADIFGDNKEWHTAPVYNECLDLVTRTVTFIMVGDKLAHNEEWLDIAKHHAVTMAIQARQLRLWPVILRPIVHWLEPQGAKLRAQVRRARQLLEPIIQERRAEKAKCLAQGIEPPRYVDSIQWFEDTAKGQWYDAAGAQLAMDFAGIYGTSDLMIGGLVDIVRHPHLIEPLRNEIRTVIGEEGWTPASLYKLKLLDSCLKESQRVKPVECATMRSYALQNVTFSNGTFVPKGELVAVAADRMSNPEVWPEPKKYDPYRYMRLREDPDKAFSAQLENTNGNHIGFGWHPRACPGRFFASKEIKIMLAFLLIRYDWKLVPNEPLQYYRHSFSVRIHPATKLMMRRRDEDL
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of monakolin K, also known as lovastatin, and which acts as a potent competitive inhibitor of HMG-CoA reductase (PubMed:18578535).  Monakolin K biosynthesis is performed in two stages (PubMed:19693441).  The first stage is catalyzed by the nonaketide synthase mokA, which belongs to type I polyketide synthases and catalyzes the iterative nine-step formation of the polyketide (PubMed:18578535, PubMed:19693441).  This PKS stage is completed by the action of dehydrogenase mokE, which catalyzes the NADPH-dependent reduction of the unsaturated tetra-, penta- and heptaketide intermediates that arise during the mokA-mediated biosynthesis of the nonaketide chain and leads to dihydromonacolin L (PubMed:19693441).  Covalently bound dihydromonacolin L is released from mokA by the mokD esterase (By similarity).  Conversion of dihydromonacolin L into monacolin L and then monacolin J is subsequently performed with the participation of molecular oxygen and P450 monoogygenase mokC (PubMed:19693441).  Finally, mokF performs the conversion of monacoline J to monacoline K through the addition of the side-chain diketide moiety (2R)-2-methylbutanoate produced by the diketide synthase mokB (PubMed:19693441).
What are the official names of this protein?
Dihydromonacolin L monooxygenase mokC, Cytochrome P450 monooxygenase mokC, Dihydromonacolin L hydroxylase, Monacolin K biosynthesis protein C, Monacolin L hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: UBID_YERP3
Sequence: MKYRDLRDFLSLLEQRGELKRISQPIDPYLEMTEIADRTLRAGGPALLFENPKGYSMPVLCNLFGTAKRVAMGMGQEDVSALRDVGKLLAFLKEPDPPKGFRDLFDKLPKFKQVLNMPTKRLNSAPCQEQVWQGEDVDLSRIPVMHCWPEDAAPLVSWGLTITRGPHKERQNLGIYRQQVLGKNKLIMRWLSHRGGALDYQEWCEAHPGERFPVAVALGADPATILAAVTPVPDTLSEYAFAGLLRGHKTEVVKCLSNDLEVPASAEIVLEGYIEQGDMAPEGPYGDHTGYYNEIDNFPVFTVTHITQRQDAIYHSTYTGRPPDEPAVMGVALNEVFVPILQKQFPEIVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGVWSFLRQFMYTKFVIVCDDDINARDWNDVIWAITTRMDPSRDTVLIENTPIDYLDFASPVSGLGSKMGLDATNKWPAETPREWGRPIKMDEDVRARIDALWDELAIFSDKDAKR
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: WECG_SALTI
Sequence: MTNNAAAPLYSLRGLPLIGWRDMSHALNYLFADGQLKQGTLVAINAEKLLTAEDNPEVRALIAAAEFKYADGISVVRSIRKKFPQAQVSRVAGADLWEALMARAGKEGTPVFFVGGKPEVLAQTEAKLRTQWNVNIVGSQDGYFTPEQRQALFARIHASGAKIVTVAMGSPKQELLMRDCREVHPHALYMGVGGTYDVFTGHVKRAPKIWQNLGLEWLYRLLSQPKRITRQMRLLRYLRWHYTGDL
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.
What are the official names of this protein?
UDP-N-acetyl-D-mannosaminuronic acid transferase, UDP-ManNAcA transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 26 family.
Protein: PILQ_NEIMA
Sequence: MNTKLTKIISGLFVATAAFQTASAGNITDIKVSSLPNKQKIVKVSFDKEIVNPTGFVTSSPARIALDFEQTGISMDQQVLEYADPLLSKISAAQNSSRARLVLNLNKPGQYNTEVRGNKVWIFINESDDTVSAPARPAVKAAPAAPAKQQAAAPSTKSAVSVSKPFTPAKQQAAAPFTESVVSVSAPFSPAKQQAAASAKQQTAAPAKQQAATPAKQTNIDFRKDGKNAGIIELAALGFAGQPDISQQHDHIIVTLKNHTLPTTLQRSLDVADFKTPVQKVTLKRLNNDTQLIITTAGNWELVNKSAAPGYFTFQVLPKKQNLESGGVNNAPKTFTGRKISLDFQDVEIRTILQILAKESGMNIVASDSVNGKMTLSLKDVPWDQALDLVMQARNLDMRQQGNIVNIAPRDELLAKDKAFLQAEKDIADLGALYSQNFQLKYKNVEEFRSILRLDNADTTGNRNTLVSGRGSVLIDPATNTLIVTDTRSVIEKFRKLIDELDVPAQQVMIEARIVEAADGFSRDLGVKFGATGKKKLKNDTSAFGWGVNSGFGGDDKWGAETKINLPITAAANSISLVRAISSGALNLELSASESLSKTKTLANPRVLTQNRKEAKIESGYEIPFTVTSIANGGSSTNTELKKAVLGLTVTPNITPDGQIIMTVKINKDSPAQCASGNQTILCISTKNLNTQAMVENGGTLIVGGIYEEDNGNTLTKVPLLGDIPVIGNLFKTRGKKTDRRELLIFITPRIMGTAGNSLRY
What is the function of this protein?
Required for type IV pilus biogenesis and competence.  Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA (By similarity).
What are the official names of this protein?
Type IV pilus biogenesis and competence protein PilQ.
What is the protein family that this protein belongs to?
Belongs to the bacterial secretin family. PilQ subfamily.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein.
Protein: DIM1_HUMAN
Sequence: MPKVKSGAIGRRRGRQEQRRELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDLPFFDTCVANLPYQISSPFVFKLLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDFSIADKIQQILTSTGFSDKRARSMDIDDFIRLLHGFNAEGIHFS
What is the function of this protein?
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle (PubMed:25851604).  Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity (PubMed:25851604).  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).
What are the official names of this protein?
Probable dimethyladenosine transferase, DIM1 dimethyladenosine transferase 1 homolog, DIM1 dimethyladenosine transferase 1-like, Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase, Probable 18S rRNA dimethylase, Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, nucleolus.
Protein: MUTS_SALAR
Sequence: MSKINMNEDIDKDFSSHTPMMQQYLKLKAQHPEILLFYRMGDFYELFYDDAKRASQLLDISLTKRGASAGEPIPMAGIPHHAVENYLAKLVNQGESVAICEQIGDPATSKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDGKGYGYATLDISSGRFRLSEPADRETMAAELQRTNPAELLYAEDFAEMALIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLVGFGVENASRGLCAAGCLLQYVKDTQRTSLPHIRSITMERQQDSIIMDAATRRNLEITQNLAGGIENTLAAVLDCTVTPMGSRMLKRWLHMPIRNTDILRERQQTIGALQDTVSELQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELHAQLETVDSAPVQALRKKMGDFAELRDLLERAIIDAPPVLVRDGGVIAPGYHQELDEWRALADGATDYLDRLEIRERERTGLDTLKVGYNAVHGYYIQISRGQSHLAPINYVRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKQLYDELFDLLLPHLADLQQSASALAELDVLVNLAERAYTLNYTCPTFTDKPGIRIIEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYMRQTALIALLAWIGSYVPAQNVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATENSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKMEGVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELESISPNAAATQVDGTQMSLLAAPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: PUR7_ROSS1
Sequence: MNLGEKLAEGKTKIVYAHPTDPTLAIIVHKDGISAGDGARRHTIPGKGALSGRTTANVFTMLNRAGVATHFVAAPEPSVMVVYRCAMIPLEVVNRRIATGSYIRRNPDVAEGTRFDPPLLEFFLKDDARHDPQMTPDEIIAQGIASADEVEQMASESRRVFLLIEEAWAAQDVVLCDLKIEFGRDTSGRLLVADVIDNDSWRIWPGGVKERMLDKQVYRNMPVVTDEGLEQVRRLYEEVAQRTDAWVNQ
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: TM129_BOVIN
Sequence: MDSPEVTFTLAYLVFAVCFVFTPTEFHSAGLTVQNLLSGWLGSEDAAFVPYHLRRTAATLLCHSLLPLGYYVGMCFAASEKQLYYPSQTPETWRAFLLLALMLPAIACTLIYYWSRDHWACHPLARTLALYALPRSGWQAVASSVNTEFRRIDKFATGVPGARVIVTDTWVMKVTTYRVHVAQQQDVRLTVTEAQQHELSPDSHLPVQLLTIRVASANPAVPAFHIRLNSTEYGELCEKLRAPIRSAANVVIHQSLGDLFLETFASLVEVNPAYSVPSSQDLEACIGCMQTQASVKLVKTCQEVAVGECQQCYCRPMWCLTCMGKWFASRQDPQRPDTWLASRVPCPTCRARFCVLDVCAVR
What is the function of this protein?
E3 ubiquitin-protein ligase involved in ER-associated protein degradation, preferentially associates with the E2 enzyme UBE2J2.  Exploited by viral US11 proteins to mediate HLA class I proteins degradation.
What are the official names of this protein?
E3 ubiquitin-protein ligase TM129, RING-type E3 ubiquitin transferase TM129.
What is the protein family that this protein belongs to?
Belongs to the TMEM129 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MDHM_BOVIN
Sequence: MLSALARPAGAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETRATVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICIISNPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANAFVAELKDLDPARVNVPVIGGHAGKTIIPLISQCTPKVEFPQDQLTTLTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETDCPYFSTPLLLGKKGIEKNLGIGKVSPFEEKMIAEAIPELKASIKKGEEFVKNMK
What are the official names of this protein?
Malate dehydrogenase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CARM1_DROYA
Sequence: MSSLRPEEARKLATAASVSPLSNCQFSGVVISSIADEQKLEFTNKYKGSCTLLCSYDSQGVVLRVVSDDDQSHVLKEYMIAADTDAAQMGRRSYAVSLDADNLVLRFASDQDQQLFRKVVENVKHLRPKSVFSQRTEESSASQYFQFYGYLSQQQNMMQDYVRTSTYQRAILGNAVDFQDKIVLDVGAGSGILSFFAVQAGAAKVYAIEASNMAQYAQQLVESNNVQHKISVIPGKIEEIELPEKVDVIISEPMGYMLYNERMLETYLHARKWLKPQGKMYPTHGDLHIAPFSDESLYSEQYNKANFWYQSAFHGVDLTTLHKEGMKEYFRQPIVDTFDIRICMAKSVRHVCDFLNDKEDDLHLISIPLEFQILQTGICHGLAFWFDVEFSGSSQNVWLSTSPTAPLTHWYQVRCLLPMPIFIKQGQTLTGRVLLEANRRQSYDVTIDLHIEGTLISSSNTLDLKNPYFRYTGAPVQAPPGTSTQSPSEQYWTQVDTQGSRNSSSMLNGGLSVNGIGDGMDITHGLMHPH
What is the function of this protein?
Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in proteins.  May methylate histone H3 at 'Arg-17' and activate transcription via chromatin remodeling (By similarity).
What are the official names of this protein?
Histone-arginine methyltransferase CARMER.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYM_CHLPD
Sequence: MLHVKRTLVTTALPYANGPVHLGHLAGVYLPADLYVRYKRLKGDNIIHIGGSDEHGVPITLTAEKEGISPRDVVDRYHGMNLDAFTKCGISFNYYGRTTSAVHHATAREFFSEIENKGMFTRKTEKQFFDKKANRFLSDRYITGTCPICSNPDANGDQCEQCGTHLSPLELINPKSKLSDATPELRETLHWYFPLGRFQSELESYVQSHDKEWRPNVINYTRTWLKQGLNDRAITRDLSWGIKLPLETPEASGKVLYVWFDAVLGYISFTKEWAAQSGQPELWREYWQDPECRMINFIGKDNVVFHTLMFPAILMAWNKGRKTDLYNLADNVPASEFMNFEGRKFSKSRNYAVYLGDFLEKFPADTLRYCIAMNYPENKDSDFSWLDFQNRTNGELADTLGNFIKRSIDFTNSRFDGKVPCECTPEEWKIPGIDWKETLEKLDQAFEAFHFREATSLGMDIARTANRFLTESEPWKVIKSDREGAAKTMAISLNLCYALALVLYPVIPETANRILAMLGVEKSIDDQLDSGKSCIAQILTPQLEKGHQLRKHSEILFTKIEDAELAPELKKIEDLLALTEEREAKNEAKAMDFSPLISFDEFLKVDLRVATVLDCQKIKKAGKLLKLQLKVGSETRQVLAGIAKHYSPEEMIGKNVILVANLAERTILNEISQGMILAVEGTDGKLFLVEPSGKEINGKKIQ
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IAH1_YEAST
Sequence: MDYEKFLLFGDSITEFAFNTRPIEDGKDQYALGAALVNEYTRKMDILQRGFKGYTSRWALKILPEILKHESNIVMATIFLGANDACSAGPQSVPLPEFIDNIRQMVSLMKSYHIRPIIIGPGLVDREKWEKEKSEEIALGYFRTNENFAIYSDALAKLANEEKVPFVALNKAFQQEGGDAWQQLLTDGLHFSGKGYKIFHDELLKVIETFYPQYHPKNMQYKLKDWRDVLDDGSNIMS
What is the function of this protein?
Plays a crucial role in the hydrolysis of isoamyl acetate in sake mash (Ref. 2).  Hydrolyzes short chain esters from acetate (C2) to hexanoate (C6), showing more specificity for shorter chain exters.  No activity for decanoate (C10) esters (PubMed:21069734).
What are the official names of this protein?
Isoamyl acetate-hydrolyzing esterase.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
Protein: MTNA_NOSP7
Sequence: MTLSTNHVYPVIWHNGAVSLIDQTRLPNEYTFVEIHRSEDMARAIKTMIVRGAPAIGVAAAYGMYLGAREIETSDRHEFLQNLDKVAQLLGSTRPTAVNLFWAISRMMKVAKETLGTVEDIKQTLFQTAQAINVEDLQTCQAIGDNGLTVLPASPEKLTLLTHCNAGALATAGYGTALGVVRSAWREGRLERLFADETRPRLQGAKLTAWECVQEGIPVTLITDNMAAHCMKQGLIHAVVVGADRIAANGDTANKIGTYSVAIAAKAHNIPFFVAAPLSTVDFELADGSKIPIEERDPTEIYQVGDTILTPEGVDFYNPAFDVTPAELITAIITENGAIAPGELVKLQLKQLV
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: EFP_MYCGA
Sequence: MASIIHAKDLRSGHTFTLDGKIYLVIENSFNKTAMREGIVKCKVKNLRTGSITTEVLTGMKLEQANIEKVKMSFVYQDQNSFVFMNNETYEQIEVPAKLLEYEKNFITENTEALIMRYEDEILGVNLPDQVVIEIDYAEDAVQGNSVNNALKKATLVTGYVIEVPQFIKSKEKVIVSTVDGKYVSRAN
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UCKD_DICDI
Sequence: MENRYISRIETISSHLLSTNDVSSQNESESITFVKPLPKNKKDHDQSIESDSSFTREKQFEEELDILGEINSKTGLFEIKQVPYQLSFDQGFFHACRAIEILTEKDPKRIICLGIAGPVGAGKTTLANKIGSLVNGVIISLQDFVKLENVKDNNYDDPVLIDFDKVISTLNELKENKTVIIPKIVNRKMESRSISLSTSKVIILEGAYALSARIRPLLDISVAITGGVHLDLIKSIMRGIVTSGKNSSKDVLAQITNVVFPMFKAFVEPDLDQAKIKIHSSFNPMSQVVEPVYVCKAKYDNNKQFFDQFLSSLNVVPVKKNFSDMYLYPPKYGVDGISQADKRNWIRIRRSEHGQFNITFYNEMMDGAVNTRPSLNFEISVKTLGGLLSLGYQIGAILNRTVEVWYDKNGVVITKEYIKELEKHFIQIKGHSRREVLDSAEKLKITGNHVPQTFLYLYFKKLKKSKNPNYSKLKPNNTNSKILKNNKDKKNL
What is the function of this protein?
Catalyzes the conversion of uridine into uridine monophosphate and cytidine into cytidine monophosphate in the pyrimidine salvage pathway.
What are the official names of this protein?
Uridine-cytidine kinase D, Cytidine monophosphokinase D, Uridine monophosphokinase D.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
Protein: ACPS_HELP2
Sequence: MIGVDIVSIARIEKCVKRFEMRFLERFLSPSEIVLCKDKFSSIAGFFALKEACSKALQVGIGKELSFLDMHISKSPKNAPLITLSKEKMDYFNIQSLSASISHDAGFAIAVVMVSSSN
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUD_PSEPK
Sequence: MTELELLGPRASGEPLGTAILKAVAEDFQVDEVLDIPLSGQGEHLWLWVEKRDLNTEEAARRLARAAGVPVRSISYAGLKDRQALTRQWFSLHLPGKADPDLSRAEDASLRVLKQVRHQRKLQRGAHSANGFTLRLTALAADHQAVDARLEQLRQQGVPNYFGTQRFGHGGGNVHDALDWAARKALPEQRNVRSRLLSAGRSYLFNQLLAARVADGSWARAQVGDLLAFTDSRSFFPAGEAECADPRLAILDLHPTGPMWGEGASPAGGAPAQLENAIGARQPALCQWLAQAGMDHERRILRLPIGGLTWHYPEPDILQLEFVLPAGCFATVVVREVVDLVSAGQTDSPCVF
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: RL14_CLONN
Sequence: MIQPQTRLKVADNTGAKEIMCIRVLGGSKRKFGNIGDVIVASVKSATPGGVVKKGEVVKAVIVRTKRGVRRADGSYIKFDENAAVVIKDDKQPRGTRIFGPIARELREKDKEFNKILSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: SSB1_MAGO7
Sequence: MSTEVYDGAIGIDLGTTYSCVATYEGSNVEIIANEQGSFTTPSFVSFTADERLIGEAAKNQAAMNPANTVFDVKRLIGRRFDDPTVKKDMESWPFKVVDEDGNPKVEVEYLGTTHKFSPQEISAMVLVKMKEIAEAKIGKKVEKAVITVPAYFNDNQRQSTKDAGAISGLNVLRIINEPTAAAIAYGLGSGKSEKERNVLIYDLGGGTFDVSLLNIQGGVFTVKATAGDTHLGGQDFDTNLLDHCKKDFQRKTKKDLSGDARALRRLRTACERAKRTLSNGTQTTLEIDSLFDGEDFSLQITRAKFEELNQTAFKGTLDPVTQVLKDAGVDKAAVDEIVLVGGSTRIPKIQKLLSDYFGGKKLEKSINPDEAVAYGAAVQAGILSGKATSAETADLLLLDVVPLSLGVAMEGNIFAPVVPRGTTVPTLKKRSFTTVADQQQTVQFPVYQGERTNCSENVSLGEFTLAPIPPMRAGEPVLEVVFEVDVNGILKVTATEKTSGRSANITIANSVGKLSTSEIENMISEAEKYKTNDEEFTKKHEAKQQLESYIARVEDIISDPTLALKLKRGQKEKIENTMSEAMAQLELGESTADDLKKKELALKRAVTKAMSSR
What is the function of this protein?
Chaperone that interacts with the histone acetyltransferase HAT1 and mediates its translocation from the nucleus to the cytoplasm during germination and starvation conditions.  Within the cytoplasm, HAT1 regulates autophagy via acetylation of the autophagy-related proteins ATG3 and ATG9.
What are the official names of this protein?
Heat shock protein SSB1, HSP70 chaperone SSB1.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RLMH_ACIAD
Sequence: MKIRILTIGQKMPAWVLTGFEDYFKRIQPFVQTQVIELPMAKRGKNDSDADILKYCQIEGESILAALKPNEVLIALEVGGRELSTEKLADTMKSWMLEGHDIALAIGGPDGLSDQVRKAAAWHWSLSKLTMPHPMVRILLIEQLYRAMSINHNHPYHRA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUT1A_ARATH
Sequence: MAISVAASSSMAVMVPRVPAVSTRCSAVPYLPPRSFGRSSFTVPLKLVSGNGLQKVELLKTRASSEETSSIDTNELITDLKEKWDGLENKSTVLIYGGGAIVAVWLSSIVVGAINSVPLLPKVMELVGLGYTGWFVYRYLLFKSSRKELAEDIESLKKKIAGSE
What is the function of this protein?
Determines thylakoid architecture by inducing membrane curvature.
What are the official names of this protein?
Protein CURVATURE THYLAKOID 1A, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the CURT family.
What are the subcellular locations of this protein?
Plastid, chloroplast, plastoglobule. Membrane; Multi-pass membrane protein. Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Located almost exclusively at grana margins.
Protein: LTAS_STAA3
Sequence: MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSVFLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASFKWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAASVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEYYGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKTSDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAKMKSPFYSHLITLTNHYPFTLDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGISENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGIDTKNYLMFGTDLFSKGHNQVVPFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKKQVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPKANSKK
What is the function of this protein?
Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate.  Is required for staphylococcal growth and cell division process (By similarity).
What are the official names of this protein?
Lipoteichoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the LTA synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Processed glycerol phosphate lipoteichoic acid synthase]: Secreted.
Protein: ZSWM5_HUMAN
Sequence: MADGGEREELLSPSPVSPAKRQCSWPSPQAHHPRGSPGAAGGGAGGVGSSCLVLGARPHLQPDSLLDCAAKTVAEKWAYERVEERFERIPEPVQRRIVYWSFPRNEREICMYSSFQYRGGPGAGAAGGAAGASPAEEGPQPPPGAAAPAGSAPGGVAAGASPGLGAGAGAAGCGGEGLPFRRGIRLLDSGSVENVLQVGFHLSGTVTELATASEPAVTYKVAISFDRCKITSVTCGCGNKDIFYCAHVVALSLYRIRKPDQVKLRLPISETLFQMNRDQLQKFIQYLITAHHTEVLPTAQKLADEILSSNSEINQVNGAPDPTAGASIDDENCWHLDEEQVKEQVKLFLSQGGYCGSGKQLNSMFAKVREMLRMRDSNGARMLTLITEQFVADPRLTLWRQQGTNMTDKCRQLWDELGALWVCIILNPHCKLEEKSCWLQQLQKWSDLDVCPLEDGNYGHELPNITNALPQSAIHSPDSLSRPRRTVFTRAIEGRELHWQDSHLQRIISSDVYTAPACQRESERLLFNSQGQPLWLEHVPTACARVDALRSHGYPKEALRLTVAIINTLRLQQQRQLEIYKHQKKELLQRGTTTITNLEGWVGHPLDPIDCLFLTLTEACRLNDDGYLEMSDMNESRPPVYQHVPVAAGSPNSSESYLSLALEVALMGLGQQRLMPEGLYAQDKVCRNEEQLLSQLQELQLDDELVQTLQKQCILLLEGGPFSGLGEVIHRESVPMHTFAKYLFSALLPHDPDLSYKLALRAMRLPVLENSASAGDTSHPHHMVSVVPSRYPRWFTLGHLESQQCELASTMLTAAKGDTLRLRTILEAIQKHIHSSSLIFKLAQDAFKIATPTDSSTDSTLLNVALELGLQVMRMTLSTLNWRRREMVRWLVTCATEVGVRALVSILQSWYTLFTPTEATSIVAATAVSHTTILRLSLDYPQREELASCARTLALQCAMKDPQSCALSALTLCEKDHIAFEAAYQIAIDAAAGGMTHSQLFTIARYMELRGYPLRAFKLASLAMSHLNLAYNQDTHPAINDVLWACALSHSLGKNELAALIPLVVKSVHCATVLSDILRRCTVTAPGLAGIPGRRSSGKLMSTDKAPLRQLLDATINAYINTTHSRLTHISPRHYGEFIEFLSKARETFLLPQDGHLQFAQFIDNLKQIYKGKKKLMLLVRERFG
What are the official names of this protein?
Zinc finger SWIM domain-containing protein 5.
Protein: MTAD_HALWD
Sequence: MTTETLIITGGHVLQLGQDPGIIEANIRVNCITGKITNIDEDPVSAQQRDANDEIIRTLDAAGCVVMPGLVNAHTHAAMTLLRGYADDKPLQAWLREDIWPAEAEMTPTGVRAGTELAIVEMIRSGTTAFADMYFHVPEVVAAIKNAGVRARVGHGVVTAGKDDEAARNDLNKGLEVAQAYDGAADDRIQTAFMPHSLTTVGEEYLQEAVSEARQDNIPIHYHANETRSEVDPIVDNHNKRPLTYASGLDMLSSSDFLAHGVHLETDEIDQLAEAGASLVHCPASNMKLASGIAPIPALLDAGVTVALGTDGAASNNDLDMFDELRDAAMLGKIGADDAAAVPAAQAIHMATAGGADALGLPGGQIKEEAVADLIVVDLDSPHLTPTHNIISHLAYAARGSDVKHTVCDGTVLMQNREIQTIDVDAVVETAETQAQSLIQRMS
What is the function of this protein?
Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively.  Is also able to deaminate adenosine.
What are the official names of this protein?
5-methylthioadenosine/S-adenosylhomocysteine deaminase, MTA/SAH deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.