PharMolix/UniProtQA huggingface dataset:
Protein: CDD_HUMAN
Sequence: MAQKRPACTLKPECVQQLLVCSQEAKKSAYCPYSHFPVGAALLTQEGRIFKGCNIENACYPLGICAERTAIQKAVSEGYKDFRAIAIASDMQDDFISPCGACRQVMREFGTNWPVYMTKPDGTYIVMTVQELLPSSFGPEDLQKTQ
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, Cytidine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: OM25_BRUSU
Sequence: MRTLKSLVIVSAALLPFSATAFAADAIQEQPPVPAPVEVAPQYSWAGGYTGLYLGYGWNKAKTSTVGSIKPDDWKAGAFAGWNFQQDQIVYGVEGDAGYSWAKKSKDGLEVKQGFEGSLRARVGYDLNPVMPYLTAGIAGSQIKLNNGLDDESKFRVGWTAGAGLEAKLTDNILGRVEYRYTQYGNKNYDLAGTTVRNKLDTQDIRVGIGYKF
What are the official names of this protein?
25 kDa outer-membrane immunogenic protein.
What is the protein family that this protein belongs to?
Belongs to the Omp25/RopB family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: LSRG_ECOSM
Sequence: MHVTLVEINVHEDKVDEFIEVFRQNHLGSVQEEGNLRFDVLQDPEVNSRFYIYEAYKDEDAVAFHKTTPHYKTCVAKLESLMTGPRKKRLFNGLMP
What is the function of this protein?
Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle.  Catalyzes the conversion of (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5-phosphonooxypentane-2,4-dione (P-HPD).
What are the official names of this protein?
(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase, Autoinducer 2-degrading protein LsrG, AI-2-degrading protein LsrG, Phospho-(S)-4,5-dihydroxy-2,3-pentanedione isomerase, Phospho-AI-2 isomerase.
What is the protein family that this protein belongs to?
Belongs to the LsrG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NORA_STAAM
Sequence: MNKQIFVLYFNIFLIFLGIGLVIPVLPVYLKDLGLTGSDLGLLVAAFALSQMIISPFGGTLADKLGKKLIICIGLILFSVSEFMFAVGHNFSVLMLSRVIGGMSAGMVMPGVTGLIADISPSHQKAKNFGYMSAIINSGFILGPGIGGFMAEVSHRMPFYFAGALGILAFIMSIVLIHDPKKSTTSGFQKLEPQLLTKINWKVFITPVILTLVLSFGLSAFETLYSLYTADKVNYSPKDISIAITGGGIFGALFQIYFFDKFMKYFSELTFIAWSLLYSVVVLILLVFANGYWSIMLISFVVFIGFDMIRPAITNYFSNIAGERQGFAGGLNSTFTSMGNFIGPLIAGALFDVHIEAPIYMAIGVSLAGVVIVLIEKQHRAKLKEQNM
What is the function of this protein?
Involved in quinolone resistance.  May constitute a membrane-associated active efflux pump of hydrophilic quinolones (By similarity).
What are the official names of this protein?
Quinolone resistance protein NorA.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MATRX_PI1HA
Sequence: MAETYRFPRFSHEENGTVEPLPLKTGPDKKAIPHIRIVKVGDPPKHGVRYLDVLLLGFFETPKQGPLSGSISDLTESTSYSICGSGSLPIGIAKYYGTDQELLKACIDLKITVRRTVRSGEMIVYMVDSIHAPLLPWSSRLRQGMIYNANKVALAPQCLPVDKDIRFRVVFVNGTSLGTITIAKVPKTLADLALPNSISVNLLVTLKAGVSTEQKGILPVLDDDGEKKLNFMVHLGIIRRKVGKIYSVEYCKNKIEKMKLIFSLGLVGGISFHVHATGTLSKTLMSQLAWKKAVCYPLMDLNPHMNLVIWAASVEITSVDAVFQPAIPKEFRYYPNVVAKSIGKIRKI
What is the function of this protein?
The M protein has a crucial role in virus assembly and interacts with the RNP complex as well as with the viral membrane.
What are the official names of this protein?
Matrix protein.
What is the protein family that this protein belongs to?
Belongs to the morbillivirus/respirovirus/rubulavirus M protein family.
What are the subcellular locations of this protein?
Virion.
Protein: M21D2_MOUSE
Sequence: MLQTPMTGMVQKLDQKLPVANEYLLLSGGVREGVVDLDLDELNVYARGTDYDMDFTLLVPALKLHDRNQPVTLDMRHSALCHSWLSLRLFDEGTISKWKGCCTIADHINGATNYFFSPTKVADWFYDSISIVLSEIQKKPQRGMPKVEKVEKNGTIISIILGVGSSRMLYDIVPVVSFKGWPAVAQSWLMENHFWDGKITEEEVISGFYLVPACSYKGKKDNEWRLSFARSEVQLKKCISGSLMQAYQACKAIIIKLLSRPKAISPYHLRSMMLWACDRLPASYLAQEDYAAHFLLGLIDDLQHCLVNKMCPNYFIPQCNMLEHLSEETVMLHARKLSSVRSDPAEHLRTAIEHVKAANRLTLKLQRRGSTTSIPSPQSDGGDPNQPDDRLAKKLQQLVTENPGKSISVFINPDDVTRPHFRIDDKFF
What is the function of this protein?
Probable nucleotidyltransferase that catalyzes the formation of cyclic dinucleotide second messenger in response to some unknown stimulus.
What are the official names of this protein?
Nucleotidyltransferase MB21D2, Mab-21 domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the mab-21 family.
Protein: PHS_SYNC1
Sequence: MERLSEQTCEICRVGAPLATAEEIAGFRSQIPDWQILTIDGVQRLSRTYRFRNFAEALEFTNRVGALAETEGHHPAIVTAWGEVTVQWWTHKIKGLHRNDLIMAAKTDALLE
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: RUTC_METED
Sequence: MPKTVVIPPGTGKPLAPYVPGTLADGVLYVSGTLPLDAEANVVHEGDAGAQTRHVLETIKGVVEAAGGSMDDVTFNHIFLKDWADYGAINAVYATYFPGEKPARYCIQCGLVKPTALVEIASVAHIGKPA
What is the function of this protein?
Involved in pyrimidine catabolism.  Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously.  RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.
What are the official names of this protein?
3-aminoacrylate deaminase RutC, 3-AA deaminase.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: RRA3_ARATH
Sequence: MAGRRDRSQQLRGSRIAIAILIGIFIGCVCAVLFPYGFFNSSSSLKASEHLSKSSNQVGSSACESPERVKMLKSDFVTLSEKNAELKKQVRELTEKLRLAEQGSDNARKQVLALGTQIKAGPFGTVKSLRTNPTILPDESINPRLAKILEEIAVDKEVIVALANANVKAMLEVQIASIKRVGITNYLVVALDDYIENLCKENDVAYYKRDPDKDVDTVGKTGGNHAVSGLKFRVLREFLQLGYGVLLSDVDIVFLQNPFSHLYRDSDVESMSDGHDNHTAYGFNDVFDEPAMGWARYAHTMRIWVFNSGFFYLRPTIPSIELLDRVADRLSKAKVWDQAVFNEELFYPSHPEYTALHASKRVMDMYEFMNSKVLFKTVRKNHELKKKVKPVIVHVNYHPDKLNRMQAVVEFYVNGKQDALDSFPDGSE
What is the function of this protein?
Plays a role in the arabinosylation of cell wall components.  Involved in the arabinosylation of extensin proteins in root hair cells (PubMed:21680836).  Extensins are structural glycoproteins present in cell walls and its arabinosylation is important for root hair cell development and root hair tip growth (PubMed:21680836, PubMed:25944827).
What are the official names of this protein?
Arabinosyltransferase RRA3, Protein REDUCED RESIDUAL ARABINOSE 3.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 77 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: DCUP_ALBFT
Sequence: MNTSTNSSAFAPLKNDTFLRACLRQATDYTPIWMMRQAGRFLPEYRATRAKAGSFMGLATNTDYATEVTLQPVERFPIDAAILFSDILTVPDAMGLGLSFALGEGPKFAHPVQDEAAVAKLAVPDMDKLRYVFDAVTSIRKALNGKVPLIGFSGSPWTLGCYMVEGAGSDDYRLVKTMLYSRPDLMHRILQINADSVAQYLNAQIEAGAQAVMIFDSWGGVLADGAFQEFSLAYTARVLAQLKREHNGARIPRIVFTKGGGMWLKEMGLLDCDVLGLDWTVNLAKARAIVGDSKALQGNMDPNVLFASPAQIAAEATRVLDSFGTPYAGEGTGPTHIFNLGHGISQHTPPEHVAALVQAVHEHSRKMRA
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYN_XANOM
Sequence: MTVVSVEHALAGKLPEGGEVTVRGWVRTLRGSAGLAFINVTDGSCFAPIQVVANDTLPNFDEIKRLTSGCSLIAKGVLVKSQGKGQSFEIQASGVEIVGWVEDPLTYPIQPKPMTPEFLREVAHLRPRTNLFGAVTRIRNCLAQAVHRFFHQNGFNWISTPIITTSDAEGAGQMFRVSTLDMVNLPRDATGNVDFSRDFFGKETFLTVSGQLNVEAYCLALSKVYTFGPTFRAENSHTTRHLAEFWMIEPEIAFADLAEDARLAEQFLKYVFRAVLDERGDDLAFLAERVDKKAISKLEAFINAPFEQIDYTDAVKLLQHAGKTFDFPVEWGLDLQTEHERWLTEEHIGRPVVVTNYPEHIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDARMAQFGLDKEHYSWYRDFRRYGSVPHAGFGLGFERLVVYVCGLSNIRDAIPYPRAPGSAEF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRIL1_RAT
Sequence: MTSQIRQNYSTEVEAAVNRLVNLHLRASYTYLSLGFFFDRDDVALEGVGHFFRELAEEKREGAERLLKLQNERGGRALFQDVQKPSQDEWGKTLEAMEAALALEKNLNQALLDLHALGSARTDPHLCDFLESHFLDKEVKLIKKMGNHLTNLRRVAGPQPAQTGVAQASLGEYLFERLTLKHD
What is the function of this protein?
Stores iron in a soluble, non-toxic, readily available form.  Important for iron homeostasis.  Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.  Also plays a role in delivery of iron to cells.  Mediates iron uptake in capsule cells of the developing kidney (By similarity).
What are the official names of this protein?
Ferritin light chain 1, Ferritin L subunit 1.
What is the protein family that this protein belongs to?
Belongs to the ferritin family.
Protein: ATPA_BURM1
Sequence: MQLNPSEISELIKSRIQGLEASADVRNQGTVISVTDGIVRIHGLSDVMQGEMLEFPGNTFGLALNLERDSVGAVILGEYEHISEGDVVKTTGRILEVPVGPELIGRVVDALGNPIDGKGPVNAKLTDAIEKIAPGVIWRKSVSQPVQTGIKSIDAMVPIGRGQRELIIGDRQTGKTAVALDAIINQKGKDLICIYVAIGQKASSIMNVVRKLEETGAMAYTIVVAASASDSAAMQYLAPYAGCTMGEYFRDRGQDALIIYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVSEEYVEKFTNGEVKGKSGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLETDLFNAGIRPAINAGVSVSRVGGAAQTKVVKKLSGGIRTDLAQYRELAAFAQFASDLDEATRKQLERGRRVTELLKQPQYQPLQVWELAVSLFSANNGYLDDLDVKQVLPFEKGLREFLKTSHADLIKRIEDTKDLSKDDEGALRAAIESFKKSGAY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: AROC_SULTO
Sequence: MPGNSFGELFRITTFGESHGPMVGVVIDGVPAGLPIKKEDIEFELSFRRPGRQFVTGRREKDEPEIVSGVYNGRTTGAPITILVKNTDVISSLYEEIHYKPRPGHADLPYIMKYGFENWDYRGGGRASARETVGRVAASAIAKKLLMLTDTWIAGHLKSLGYVELNEPVTFEEVLCSKYSPVRASKKWLEKKYEELVKQATVEGDSWGGIAEIIVRNPPIGLGEPVFDKLKADLAKALLSIPAVMGFEYGLGFNAAKMKGSEANDEIVKKGDKYRWKFNNSGGILGGLSTGEDILVRCAFKPTSSIRKPQKTIDLRTGEETTISVIGRHDPAVAIRGVSVAEAMVSLVIVDHAMRAGYIPTVRISDDQIKIIEERWNKYISLCKPTQVSQ
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: BIOD_CHLTE
Sequence: MLFQKEKVMKGQVLAISGIDTGIGKTVVTGLLARCFAETGWRTITQKIAQTGCEGVSEDIAEHRKLMGIDLQEADLDGTTCPYLFRFPASPHLAATVEGREIDFMTIRRSTFRLQKLYDLVLLEGVGGLLVPLTPELLFADYVRDAGYGLVLVSASRLGSINHTLLSLEACARRGIPVRAIVYNRYFEADERIAANTREVIAAALKRYGFGEAPVIDLNTSGLSAEPGDLQRILNPPGQ
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_RICCN
Sequence: MIQMQSILEVADNSGAKKVMCIKVLGGSHHMVAKLGDVIVVSVKDAIPGGKVKKGDVYKGVIVRTKTGVVRPDGSTIKFDQNALVLLNKQDEPIGTRVFGPVTRELRAKKYVRIMSLAEEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: PSMG1_BOVIN
Sequence: MAATFFGEVVRTPCRAGTEEEEEEEDGNRETPEDREVRRQLARKREVRLFRRQTKTTLEVSLLEKHPCSKFIIAIGNNAVAFLSSFVMNSGAWEEVGCAKLWNEWCRTTDTAHLSPTEAFCVFYHLKSNPSVMLCQCSCYVAEDQQYQWLEKVFGSCPRKNMQVTILTCRHVTDYKTSESTSSLHTPFLKALKTQNFKEPPFCSLLEQPNIVHDLPAAVLSYCQVWRIPAVLYLCYTDVMKLDLITIEAFKPVLSSKSLKCLVKNIPQSTEILKKLMTTNEIQSNIYT
What is the function of this protein?
Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2.  The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization (By similarity).
What are the official names of this protein?
Proteasome assembly chaperone 1.
What is the protein family that this protein belongs to?
Belongs to the PSMG1 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: T2S2_SHISO
Sequence: MQRLSPGEFKTLISKERKSHFITPFALVYKTFCDLGYDQKNSDYFLNNPSEYIIAMRKNCWKEFEPFEKEFTTRMLSYLIDEERIKDMSPYDAIRDFTMEYPTHIYDLALSNTQSRRSRAGKEFESILELLMMGAGIPVDVQGAIGKSFFQKNQIGKLVDLVMPGVVQYTSNKRNTMLISAKTTLRERWQEVPEEVNRTGIREMYLATLDDSFSEETINILYEANVVVVTTIENKNFKYKNNNRVLTFEDMLQSAMELSRKWNNVSYTDSEKEEIQRSILKQIEKYSDFPYVVNYYRNRLSALFD
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-CCNGG-3' and cleaves before C-1.
What are the official names of this protein?
Type II restriction enzyme SsoII, R.SsoII, Endonuclease SsoII, Type-2 restriction enzyme SsoII.
Protein: RL5_BACC1
Sequence: MNRLKEKFQKEITPALMSKFNYKSVMQVPKIEKIVINTGVGDAVSNSKALDNAVEELTQIAGQKPVVTRAKKSIAGFRLREGMPIGAKVTLRGEQMYEFFDKLVSVSLPRVRDFRGVSKKSFDGRGNYTLGVKEQLIFPEIDYDKVSKVRGMDIVIVTTANTDEEARELLTQFGMPFQK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: LUXS_SHESW
Sequence: MPLLDSFTVDHTRMNAPAVRVAKHMSTPKGDAITVFDLRFCTPNKEILSERGIHTLEHLFAGFMRDHLNSSNVEIIDISPMGCRTGFYMSLIGEPTEHQVAVAWLAAMEDVLKVVEQSEIPELNEYQCGTYEMHSLEQAQEIARNIIAAGVSVNRNDDLKLSDEILGKL
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: CHEB1_XANCP
Sequence: MTLETPVRVLIVDDSAVVRQMLTEILSRDPGIEVVGSAADPLLAREKIKRLNPDVITLDVEMPRMDGLVFLENLMRLRPTPVVMISSLTERGADTTLQALSLGAVDFISKPKIDVARGLEGYAEEIVSKVKMAAKAKVSALNRPSAPKITLDMQSAPVPGSALRFRTTDRLIAIGASAGGTEALRVVLEHMPADAPAVVMTQHLPASFSTAFAERLNRHSAMSVREASDGEAILPGHAYLPPGGQHLRIIRDGARWRCRIDDGPPVNRHKPAVDVLFRSVAANAGPNAVGAILTGMGDDGARGLLEMLQAGAPTLVQDEASSVVWGMPGAAYKLGAAQEVVPLERVAERLIALSAQAR
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 1.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS8_STRMU
Sequence: MIRGLRQIEPYVAGVQPAERKMIKLNTNENAYGASPKVREALANFDVDNLRKYSTLEQADLRAALANNLKVKPEQLMIANGSDDVLSIAFLAFFNNDEPVLFPDLTYGFYKVWADLYRVNYHEIPLAEDFTINTEDYLADNGGIILTNPNAPTGIYKPLNEIEKLLKANQDTVVIIDEAYISFGGQSALSLLNKYNNLVITRTFSKDAALAGLRVGYAIANEPLIAVMNAVKHSINPYSVDLLAERLATAAVEDWSYYQENAKKIQKTRAWFSEQLVKQGFDVLPSQANFVLTKPHDLATAKLFEELEARKIYVRYFPKVERIKDYLRISMGTQEEMEEVVKAIEEIRG
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: SECY_ECO57
Sequence: MAKQPGLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGIDAAVLAKLLEQQRGTIIEMFNMFSGGALSRASIFALGIMPYISASIIIQLLTVVHPTLAEIKKEGESGRRKISQYTRYGTLVLAIFQSIGIATGLPNMPGMQGLVINPGFAFYFTAVVSLVTGTMFLMWLGEQITERGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFLVLLLVAVLVFAVTFFVVFVERGQRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIPAIFASSIILFPATIASWFGGGTGWNWLTTISLYLQPGQPLYVLLYASAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTRLTLVGALYITFICLIPEFMRDAMKVPFYFGGTSLLIVVVVIMDFMAQVQTLMMSSQYESALKKANLKGYGR
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
Protein: XERS_STRPS
Sequence: MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKEYDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVSQTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQKLFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLDLRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLYRGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHASTQVTDLYTHIVNDEQKNALDSL
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.
What are the official names of this protein?
Tyrosine recombinase XerS.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_CORGL
Sequence: MSKNSKAYREAAEKIDAGRIYSPLEAANLVKETSSKNYDASIDVAIRLGVDPRKADQLVRGTVSLPNGTGKTVRVAVFAQGEKATEAEAAGADFVGTDELVEKIQGGWTDFDVAIATPDQMAKIGRIARVLGPRGLMPNPKTGTVTNDVAKAIEEVKGGKISFRVDKASNLHAAIGKASFDAKKLAENYGALLDEIIRIKPSSAKGIYVKRVTLSSTTGPGVEVDTHVTKNYAEEA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: LPXH_HAEI8
Sequence: MKHSYFISDLHLSETQPELTALFVDFMQNLAPQAERLYILGDLFDFWIGDDEQSALIQQVKDLIKSVSNQGVQCYFQHGNRDFLIGERFAKDTGVQLLPDYQLITLYDKKILLCHGDTLCIDDEAYQQFRRRVHQKWLQRLFLCLPLKVRVIIAEKIRAKSNQDKQAKSQEIMDVNQAFTAEKVQEFDVNLLIHGHTHREAIHQQEEFTRIVLGDWRKNYASILKMDESGEFGFIKD
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ALDH2_HUMAN
Sequence: MLRAAARFGPRLGRRLLSAAATQAVPAPNQQPEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS
What is the function of this protein?
Required for clearance of cellular formaldehyde, a cytotoxic and carcinogenic metabolite that induces DNA damage.
What are the official names of this protein?
Aldehyde dehydrogenase, mitochondrial, ALDH class 2, ALDH-E2, ALDHI.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CTDS_DICDI
Sequence: MNSSPITQVSNPNDSLNHSSTNLIPSSHNSLNNYPQKSVKGNRKKKGSIINKLFCCFVPSNDQNNGNNINTDNGASNNDKLQQQKQYNQQQQQQYNQHQQQQQQQQQQQQYINKDSSQQNGEIPLMVPMIPRHVGLKTLVLDLDETLVHSSFKPVHNPDFIVPVEIEGTIHQVYVVKRPFVDDFLRAIAEKFEIVVFTASLAKYADPVLDFLDTGRVIHYRLFRESCHNHKGNYVKDLSRLGRDLKSTIIVDNSPSSYLFHPENAIPIDSWFDDKDDRELLDLLPLLDDLIKVEDVRLVLDESRNN
What is the function of this protein?
May function as a phosphatase involved in the regulation of cell growth and differentiation.
What are the official names of this protein?
Probable C-terminal domain small phosphatase, Developmental gene 1148 protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL11_RICCN
Sequence: MSQKAIKGYINLIIPAAGATPAPPIGPALGQRKVNIAAFCKDFNDATQGMEKGIPLPTVITVYEDSSFSFKIKTPPASYFLKKYAKITKGSSATKKEAVVGKVTMDDCREIAKLKMPDLNTKNIEAATKIICGSAASMGLEVVGN
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: SYFA_XYLF2
Sequence: MVINDIESLTAQALAEVAAAQNLDHLEFLRVALLGKNGSITLQLKQLGKLPVEQRKAIGEKLNRVRDLISDALMDRKAALESAALSKRLIDERVDVTLPGRRGERAGLHPVTRTLERITEIFARLGYELVEGPEIEDDWHNFEALNFPLHHPARAMHDTFYFGDGRLLRTHTSGVQVRYMSDHRPPLRMIAAGKVYRSDSDQTHSPMFHQIEGLLLDKHATFVDLKGTLSEFLRAFFERDFEVRFRPSYFPFVEPGAEVDIAWQQSDSSVRWLEVLGCGMVHPNVLKNVGIDSECYTGFAFGLGVERFAMLRYGVDDLRAFFENDVRFLRQFS
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.