PharMolix/UniProtQA huggingface dataset:
Protein: Y547_MYCPN
Sequence: MSTVNLSNFIDMLRLGCKNIANNFEYINQLNVFPVPDGDTGTNMKVTLSEAFKKLESEISHIKSFSDLGKSFTRDLLLFSRGNSGVIFSQIMKGFFSDMISTKTATETELGIEDFATAFIKAEEVAYKNVSKPVEGTMLTVIRLISTDFKNQKNRAKTVQKLFEQVIKTAWQTVKKTPQMLPVLKASGVVDSGAYGFACFLEGMLSFYGEKATLNDGKLTSAELSQMTISGEKHVTEEEFGYCTEYVLKLGMSVSQEVEKQKFNQKKFESKVSKIATSVVVASDKDNGFVKVHAHTEKPNLLLELGLNYGEFELVKIENMNLQVAKQKPAPVKRNIKPAIVVTVPTEAFADRIREDYDIQAILCTDDTGAPSVFSLLEAVKLTHSSNIIFLLHDKNYFLSANEALKQLKHQKISADCVMTTNPIESLAALTVFNSDLNIHTNVKTMRRFVKGFASATITQASKKYKENRIEVNKGDFIAVANNSICVSEKELVQCVFNTIDHLLKKVKKPEFLLAYYGKDITAEEAEAMKEKIEKKYKLFCEFSPGEQKVFSYILGIQ
What are the official names of this protein?
Uncharacterized protein MG369 homolog.
Protein: FFSD_ASPFV
Sequence: MLQDIVEQWQIMQQALAPLRLTRWQLTKMFAAQVYRDHPVGALLGISLSVVLLLWVISVVTRPKKLEDVLGLPVLGGSRTLKSDFLRIIEEGKQRYPDTPYIVNASGLQYVVYPPIFFDEIKRLTEQEASAQDFFHTVTYGQWTHIGAETDALWKTIAVDLARSVPVKVPSKQKDARIAFDKYVGYCPESKPVTIFDTMMKIVATTNACSFVGREVGTGEWPQVVQQLPMSVYFAVMTLSIVPRIFRPVLLPIVLIPALLVQRKMRKILAPGIRQDMEEYERAADRKELLKPTEDGKLPFTQWLMARYKPGEATAHQLATDHLLTSFESTVSTAATLYNMILDLAVRPELQDELRQEVEEIMVDGKLPATHLKELKKMDSMMRETFRVNPFALFSLYRITRKPIQLSSGPKLPAGTILCVDSHHINNSAELFPEPAKFDPYRFLKKREEPGAENRFQFVSTGPTDPNWGDGTQACPGRFFANSTLKVCLAHVLLKYNVSLREGQERPKMVSMPNGIWAPDMAAQVLFQSRD
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the cytotoxic leucine-containing cytochalasans, including aspochalasin C, aspochalasin E, TMC-169, flavichalasine F, aspergillin PZ, aspochalasin M and flavichalasine G (PubMed:32913332).  The first step in the pathway is catalyzed by the hybrid PKS-NRPS ffsA that utilizes 8 units of malonyl-CoA to iteratively assemble the octaketide chain before addition of L-leucine by the C-terminal NRPS modules (PubMed:32913332).  Because ffsA lacks a designated enoylreductase (ER) domain, the required activity is provided the enoyl reductase fssC (Probable).  The methyltransferase (MT) domain of ffsA catalyzes the alpha-methylation at C10 and C14 using S-adenosyl-L-methionine as the methyl-donating cosubstrate (Probable).  Reduction by the hydrolyase ffsE, followed by dehydration and intra-molecular Diels-Alder cyclization by the Diels-Alderase ffsF then yield the required isoindolone-fused macrocycle (By similarity).  A number of oxidative steps catalyzed by the tailoring cytochrome P450 monooxygenase ffsD, the FAD-linked oxidoreductase ffsJ and the short-chain dehydrogenase/reductase ffsI, are further required to afford the final products (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase ffsD, Cytochalasans biosynthesis cluster protein ffsD.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YIDD_SHESM
Sequence: MAQTQSPLQWLATTFIRGYQIFISPLLGPRCRFNPTCSHYAIEAIKVHGTAKGCWFALKRILKCHPLHPGGSDPVPPKNDRCNK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: METK_MYCPA
Sequence: MSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAQDPRSRVAVETLVTTGQVHVVGEVTTTAKEAFADITNTVRERILDIGYDSSDKGFDGASCGVNIGIGAQSPDIAQGVDTAHETRVEGAADPLDAQGAGDQGLMFGYAIKDTPEMMPLPIALAHRLSRRLTEVRKSGVLPYLRPDGKTQVTIEYEDDVPVRLDTVVVSTQHAADIDLENTLTPDIREKVLNTVLDDLAHDTLDTSSTRLLVNPTGKFVVGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKNIVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTATVDPVKIEKIVPEVFDLRPGAIIRDLDLLRPIYAQTAAYGHFGRTDVELPWEQLNKVDELKRAV
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR2_CLOAB
Sequence: MKILLIGSGGREHAMAWKMAQNKSVERIYCAPGNGGTAKENKCENVNLEKTEELIEFASKNNIDLTVVGPEAPLVDGIVNEFKEKGLKIFGPGKVGAQLEGSKSFSKDFMKKYNVKTAEYAVFENSEESLEYLKKCTYPIVIKADGLAAGKGVVICEDYKLAEETIKAFMVKDVFKGSGKKVVIEEYLEGVEASILSITDGKAIIPFVSSKDHKQIFDGNKGPNTGGMGAISPNPYCTEEVLKSFEEEILKPTLIGIQEERMDFTGIIFFGLMITKKGVYLLEYNVRLGDPETQVVLYLMKSDFVDLINAAMDKKLSDFDIEWYDGNACCVVAASKGYPKNYSTGYEISGIDDAGDKVFCAGVKLENGVYKTSGGRVLCASARGITLDEAIKKAYTDIERIKFDGIYYRKDIGKSK
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: ISPG_PSELT
Sequence: MSKTLKIANIFLGGNNPVVIQSMTNTKTQEVEKTIRQINDLMSAGCEMVRVSVPDLESAQSIKLIKQKVRIPIIADIHFDHKLAIEAIKSGADKIRINPGNIGPEWKIRELAKVAKDYGVAIRVGSNSGSLRKDYEQKHDRATALAESALKEVSILEKEGFYNIVISAKSSDVIETIKANEYISQKVDYPIHLGVTEAGTHITSTVKSSIAIGYLLLKGIGDTIRVSISGDPVEEVIIARKILMSLHLRKEGQVIACPTCSRCEINVEQIAKTIEALVEKNNLTVAVMGCVVNGIGEGGHADIGVAGTKNGAVLFMKGKIVKTIPKEKIVEVLTELIVNRTDKLG
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: TLR9_MOUSE
Sequence: MVLRRRTLHPLSLLVQAAVLAETLALGTLPAFLPCELKPHGLVDCNWLFLKSVPRFSAAASCSNITRLSLISNRIHHLHNSDFVHLSNLRQLNLKWNCPPTGLSPLHFSCHMTIEPRTFLAMRTLEELNLSYNGITTVPRLPSSLVNLSLSHTNILVLDANSLAGLYSLRVLFMDGNCYYKNPCTGAVKVTPGALLGLSNLTHLSLKYNNLTKVPRQLPPSLEYLLVSYNLIVKLGPEDLANLTSLRVLDVGGNCRRCDHAPNPCIECGQKSLHLHPETFHHLSHLEGLVLKDSSLHTLNSSWFQGLVNLSVLDLSENFLYESITHTNAFQNLTRLRKLNLSFNYRKKVSFARLHLASSFKNLVSLQELNMNGIFFRLLNKYTLRWLADLPKLHTLHLQMNFINQAQLSIFGTFRALRFVDLSDNRISGPSTLSEATPEEADDAEQEELLSADPHPAPLSTPASKNFMDRCKNFKFTMDLSRNNLVTIKPEMFVNLSRLQCLSLSHNSIAQAVNGSQFLPLTNLQVLDLSHNKLDLYHWKSFSELPQLQALDLSYNSQPFSMKGIGHNFSFVTHLSMLQSLSLAHNDIHTRVSSHLNSNSVRFLDFSGNGMGRMWDEGGLYLHFFQGLSGLLKLDLSQNNLHILRPQNLDNLPKSLKLLSLRDNYLSFFNWTSLSFLPNLEVLDLAGNQLKALTNGTLPNGTLLQKLDVSSNSIVSVVPAFFALAVELKEVNLSHNILKTVDRSWFGPIVMNLTVLDVRSNPLHCACGAAFVDLLLEVQTKVPGLANGVKCGSPGQLQGRSIFAQDLRLCLDEVLSWDCFGLSLLAVAVGMVVPILHHLCGWDVWYCFHLCLAWLPLLARSRRSAQTLPYDAFVVFDKAQSAVADWVYNELRVRLEERRGRRALRLCLEDRDWLPGQTLFENLWASIYGSRKTLFVLAHTDRVSGLLRTSFLLAQQRLLEDRKDVVVLVILRPDAHRSRYVRLRQRLCRQSVLFWPQQPNGQGGFWAQLSTALTRDNRHFYNQNFCRGPTAE
What is the function of this protein?
Key component of innate and adaptive immunity.  TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms.  TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides.  Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:18931679, PubMed:21402738, PubMed:14993594, PubMed:17474149, PubMed:25686612, PubMed:18820679).  Plays a role in defense against systemic mouse cytomegalovirus infection (PubMed:14993594).  Controls lymphocyte response to Helicobacter infection (PubMed:17474149).  Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production (By similarity).
What are the official names of this protein?
Toll-like receptor 9.
What is the protein family that this protein belongs to?
Belongs to the Toll-like receptor family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endosome. Lysosome. Cytoplasmic vesicle, phagosome. Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist (PubMed:18305481). Exit from the ER requires UNC93B1 (PubMed:18820679). Endolysosomal localization is required for proteolytic cleavage and subsequent activation (PubMed:18931679, PubMed:18820679). Intracellular localization of the active receptor may prevent from responding to self nucleic acid (PubMed:18820679).
Protein: RTCB_RAT
Sequence: MSRNYNDELQFLDKINKNCWRIKKGFVPNMQVEGVFYVNDALEKLMFEELRNACRGGGVGGFLPAMKQIGNVAALPGIVHRSIGLPDVHSGYGFAIGNMAAFDMNDPEAVVSPGGVGFDINCGVRLLRTNLDESDVQPVKEQLAQAMFDHIPVGVGSKGVIPMNAKDLEEALEMGVDWSLREGYAWAEDKEHCEEYGRMLQADPNKVSPRAKKRGLPQLGTLGAGNHYAEIQVVDEIFNEYAAKKMGIDHKGQVCVMIHSGSRGLGHQVATDALVAMEKAMKRDKIIVNDRQLACARIASPEGQDYLKGMAAAGNYAWVNRSSMTFLTRQAFAKVFNTTPDDLDLHVIYDVSHNIAKVEQHVVDGKERTLLVHRKGSTRAFPPHHPLIAVDYQLTGQPVLIGGTMGTCSYVLTGTEQGMTETFGTTCHGAGRALSRAKSRRNLDFQDVLDKLADMGIAIRVASPKLVMEEAPESYKNVTDVVNTCHDAGISKKAIKLRPIAVIKG
What is the function of this protein?
Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester.  May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
What are the official names of this protein?
RNA-splicing ligase RtcB homolog, 3'-phosphate/5'-hydroxy nucleic acid ligase, p55.
What is the protein family that this protein belongs to?
Belongs to the RtcB family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Enters into the nucleus in case of active transcription while it accumulates in cytosol when transcription level is low.
Protein: RS7_HAEDU
Sequence: MPRRRSVEPRKILPDPKFGSELLAKFINVLMVDGKKSTAESIIYGALETLSQRTGKEALEAFEAALENVRPTVEVKSRRVGGSTYQVPVEVRPARRNALAMRWIVEAARKRGDKSMALRLANELSDAADNKGTAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: SYDP_AERHH
Sequence: MSDQVLSALEHFFLRWQRDGEARRGLPLCEWEADWRSPCELDEPKEGRVAWRPHRRAEPADFTAMNEALELTLHPAAQALFGGWFSRPVPCLYKGLRLEFVLPWNEADLDLLKENLIGHLLMLRKLKRSPSLFIATTRNEMTLVSLDNESGQVWLEWLDSGRRLVLAPSLPAFLERLETLPQ
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: ARGP_SHIB3
Sequence: MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLENMFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSLATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLGALDYLFVSSKPFAEKYFPNGVTRSALLKAPVVAFDHLDDMHQAFLQQNFDLPPGSVPCHIVNSSEAFVQLARQGTTCCMIPHLQIEKELASGELIDLTPGLFQRRMLYWHRFAPESRMMRKVTDALLDYGHKVLRQD
What is the function of this protein?
Controls the transcription of genes involved in arginine and lysine metabolism.
What are the official names of this protein?
HTH-type transcriptional regulator ArgP.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: GL_HCMV6
Sequence: MCRRPDCGFSFSPGPVVLLWCCLLLPIVSSVAVSVAPTAAEKVPAECPELTRRCLLGEVFQGDKYESWLRPLVNVTGRNGPLSQLIRYRPVTPEAANSVLLDDAFLDTLALLYNNPDQLRALLTLLSSDTAPRWMTVMRGYSECGDGSPAVYTCVDDLCRGYDLTRLSYGRSIFTEHVLGFELVPPSLFNVVVAIRNEATRTNRAVRLPVSTAAAPEGITLFYGLYNAVKEFCLRHQLDPPLLRHLDKYYAGLPPELKQTRVNLPAHSRYGPQAVDAR
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Acts as a functional inhibitor of gH and maintains gH in an inhibited form.  Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH (By similarity).  In human cytomegalovirus, forms two distincts complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope.  The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA.  The gH-gL-UL128-UL130-UL131A pentamer is essential for viral entry in epithelial, endothelial and myeloid cells via interaction with host NRP2 (By similarity).
What are the official names of this protein?
Envelope glycoprotein L, gL.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein L family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Extracellular side. Host cell membrane; Peripheral membrane protein; Extracellular side. Host Golgi apparatus, host trans- Golgi network. Note=gL associates with the extravirion surface through its binding to gH. During virion morphogenesis, this protein probably accumulates in the host trans- Golgi where secondary envelopment occurs.
Protein: ENO_STRPC
Sequence: MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMITLDGTPNKGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKERGLVTAVGDEGGFAPKFEGTEDGVETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQVDYLEELVNKYPIITIEDGMDENDWDGWKVLTERLGKRVQLVGDDFFVTNTEYLARGIKENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: PGC1_YEAST
Sequence: MVEIVGHRAFKARYPENTLLAFEKAYAAGADVIETDLQMTSDGMVVVNHDSDTGRMWDKNLVIGESTWEEVKRLRCKEDGSLAMMTLKEILTWAVCHPGAKLMLDIKFTNEKIIMIKTFVIMLEVKNDLKFWQERITWGLWLLDWYDFGIETGVLKDFKVIVISLSLDIASQFVKRSLTLNDPHYKLFGISVHFVSSWTSQFRLRLLPVLMKNDIKVYLWTVNKPIDFKYLCELPIHGAITDDPIKARKLCDGHTVAKKPTAEKKFVAPSLASVDGLRFHAFIKVYNILCTLLYSKWVHIKLCGWSIAYVIFLFLRTIHFL
What is the function of this protein?
Phosphatidylglycerol phospholipase required for the removal of excess phosphatidylglycerol (PG) via a phospholipase C-type degradation mechanism.
What are the official names of this protein?
Phosphatidylglycerol phospholipase C.
What is the protein family that this protein belongs to?
Belongs to the glycerophosphoryl diester phosphodiesterase family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass type IV membrane protein. Lipid droplet.
Protein: FBSP1_DROER
Sequence: MVDPVAALCNYNVLEVIFSYLELEDLSHCSQVCKSWYHFLNDENSDVWRWHCLNKLPKEALKSDLLSSVSTYKTKLRAYFHAWSPNDCSRNVYIKPNGFTLHRNPVAQSTDAARGKIGFRHGRHTWEVIWEGPLGTVAVIGISTKEAALQCHGYVALLGSDDQSWGWNLVENHLLHNGDMQGSYPLLNNAPKYQVGERIRVILDCEDNTLSFEKNYEFLGVAFRGLPDKKLYPTVSAVYGNTEVSMVYLGTPLDG
What is the function of this protein?
Required in the presynaptic motoneuron to down-regulate the levels of wnd and restrain synaptic terminal growth at the neuromuscular junction (NMJ).
What are the official names of this protein?
F-box/SPRY domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the FBXO45/Fsn family.
What are the subcellular locations of this protein?
Synapse.
Protein: RNPH_ACIAD
Sequence: MRLDQRALDQLRDVKITRNYTRYAEGSVLVEFGHTKVLCTASIDNSVPRFLKGQGQGWVTAEYGMLPRSTHTRSDREAARGKQTGRTQEIQRLIGRSLRAMVDLKKLGENTITIDCDVIQADGGTRTAAITGAAVALIDAMNVLLEKKKIKQDPLKGLVAAISVGIYQDEVLLDLCYEEDSNCQTDLNVVMTQAGEFIEIQGTAEEKPFTRTQANAMLEVAEKGIQELIKKQQQALGW
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: RL23_ALKCK
Sequence: MSNARDIIKRPVITERSTELMEDKKYTFEVDVRANKTQIKDAIEEIFEVKVTNVNTVNYKGKAKRFGRYTGFTPKRKKAIVQLSADSKELDFFEV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: CARA_HALSA
Sequence: MSDAYLALETGDVVEATARAPGMARGELVFTTAYTGYEESLTDPSYEAQVLTFAYPLIGNYGVRPERTESDRVHPSAVVARELTDDVADWLRTEGVPAVDGIDTRDLVLDIRDGGAMQVGIAAGPDASPATARAQLADCPRLSARTEIGAHVSVDTAETHGNGDTTVALVDCGAKRSIIDAFVARGATVHRLPYDATPADIAAVDPDLLFISNGPGDPANFDAAEHLVDEYIGTVPIAGICLGQQIVARALGGDTEKMDFGHRGVNQPVLDHDSGRVVMTTQNHGYTVADPGDLTVTQVNVNDGTPEALDSAPLDVLTRQYHPEANPGPHDTRGFFDDVLAMADASYTPATAD
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: DAPE_ORITI
Sequence: MISKKLIIELLKQLISFKSVTPNDNGAIDFITNLLVKQGFKVYVKEFGQEYKVKNLYGYFGNGQPNICFAGHIDVVPAGFIEQWKYPPFCATQYKDKIYGRGVVDMKGAISAMLSAVFCFIDNNNDFNGTISFLITADEEGEALFGTKKMLEWINKQGHKIDFTILGEPTCTDKIGDTIKIGRRGSINFDLKVFGKQGHVAYPHLAINPNHLIVKILNSFIGSKIDEGNEFFAPSNLEVVSIDTNNNITNIIPEIAQSKFNIRFNDIHTNEQLLEIVKKNIEQFTTNYDLQSSCRSRPFLAKMSPYIFSFKELVHKVTKIKPEFSTSGGTSDAYFFKDYSPIVEFGLLNTMAHKINEYCLINDLQTLCRVYYNALCLFLMSNSKFRTN
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: CYB_OTOBE
Sequence: MTNIRKTHPLMKIVNHSFIDLPTPSNISTWWNFGSLLGLCLTIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNFGWLIRYIHANGASMFFICLFLHVGRGLYYGSYTYFETWNVGIILLFVVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGNTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVMVHLLFLHETGSNNPSGLISDSDKIPFHPYYTIKDILGALLLILILMILVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVSSILILLTFPLLHLSKQRSMMFRPLSQLMFWILVADLLTLTWIGGQPVEYPFIIIGQLASILYFTIILLILPAVSLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CTL1_RAT
Sequence: MGCCSSASAAQSSKREWKPLEDRSCTDIPWLLLFVLFCIGMGFICGFSVATGAAARLVSGYDSYGNICGQRNAKLEAIANSGLDHTHRKYVFFLDPCNLDLINRKIKSMALCVAACPRQELKTLSDVQKFAEINGSALCSYNIKPSEYTLTAKSSAFCPKLPVPASAPIPFFHRCAPVNISCYAKFAEALITFVSDNSVLHRLISGVMTSKEIILGLCLLSLVLSMILMVIIRYISRVLVWILTILVILGSLGGTGVLWWLYAKQRRSPKETVIPEQLQIAEDNLRALLIYAISATVFTVILFLIMLVMRKRVALTIALFHVAGKVFIHLPLLVFQPFWTFFALVLFWAYWIMTLLFLGTTGSAVQNEQGFVEYKISGPLQYMWWYHVVGLIWISEFILACQQMTVAGAVVTYYFTRDKRNLPFTPILASVNRLIRYHLGTVAKGSFIITLVKIPRMILMYIHSQLKGKENACARCMLKSCICCLWCLEKCLSYLNQNAYTATAINSTNFCTSAKDAFVILVENALRVAAINTVGDFMLFLGKVLIVCSTGLAGIMLLNYQQDYTVWVLPLIIVCLFAFLVAHCFLSIYEMVVDVLFLCFAIDTKYNDGSPGREFYMDKVLMEFVENSRKAMKEAGKGGAADARKLKPMASGASSA
What is the function of this protein?
Probable choline transporter.  May be involved in membrane synthesis and myelin production.
What are the official names of this protein?
Choline transporter-like protein 1, Solute carrier family 44 member 1.
What is the protein family that this protein belongs to?
Belongs to the CTL (choline transporter-like) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: 3BHS4_RAT
Sequence: MPGWSCLVTGAGGFLGQRIVQLLVQEKDLKEVRVLDKVFRPETREEFFNLGTSIKVTVLEGDILDTQCLRRACQGISVVIHTAALIDVTGVNPRQTILDVNLKGTQNLLEACVQASVPAFIYCSTVDVAGPNSYKKIILNGHEEEHHESTWSNPYPYSKKMAEKAVLAANGSILKNGGTLHTCALRPMYIYGERSPFLSVMILAALKSKGILNVTGKFSIANPVYVGNVAWAHILAARGLRDPKKSQNVQGQFYYISDDTPHQSYDDLNYTLSKEWGLHLDSSWSLPLPLLYWLAFLLEIVSFFLHPVYNYRPSFNRHLVTLSNSKFTFSYKKAQRDLGYKPLVSWEEAKQKTSEWIGTLVEQHRETLDTKSQ
What is the function of this protein?
3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids.  The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.
What are the official names of this protein?
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 4, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type IV, 3-beta-HSD IV.
What is the protein family that this protein belongs to?
Belongs to the 3-beta-HSD family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
Protein: RL1_LACP3
Sequence: MAKKGKKYLEAAKAVDPTKQYTPEEAVDLLKKIDFAKFDETVEVAYRLNVDPKQADQQIRGAVVLPNGTGKTAKVIVFAQGDQAKAAEDAGADIVGAEDLVQKIQDGWLDFDVAVATPPMMAQVGRLGRVLGPKGLMPNPKTGTVTMDTAKAVKDIKAGQVAYRVDKAGIIHAPIGKKSFDADKLLENFKAMNDIVLKARPASTKGIYIKSLALTATMAPGIKVNPSDF
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: GCST_KLEP7
Sequence: MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQIDEHHAVRGDAGMFDVSHMTIVDFHGSRIREFLRYLLANDVAKLTTPGKALYTGMLTASAGVIDDLIVYFLSEDYFRLVVNSATREKDLAWISEQAEPYGLEITVRDDLSLIAVQGPQAKAKAATLFTDAQRQAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIVMPNEQAADFWRGLLDAGVKPCGLGARDTLRLEAGMNLYGQEMDEGVSPLAANMGWTIAWEPADRNFIGREALEMQREKGTEQLVGLVMTEKGVLRGGLPVRFTDSDGNQKEGIITSGTFSPTLGYSIALARVPAGIGDTAVVQIRNREMPVKVTKPGFVRNGKAIV
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.