PharMolix/UniProtQA huggingface dataset:
Protein: TRPB_DINSH
Sequence: MPDDLINSFMTGPDENGRFGDFGGRFVSETLMPLILELERQYEFAKTDQAFWDEMHHLWTHYVGRPSPLYFAERLTERLGGAKVYLKRDELNHTGAHKINNVLGQIILARRMGKTRIIAETGAGQHGVATATVCAKFGLKCVVYMGAHDVERQAPNVFRMKLLGAEVVPVTSGRGTLKDAMNDALRDWVTNVRETFYCIGTVAGPHPYPAMVRDFQAIIGQEAREQMMEAEGRLPDTLIAAIGGGSNAMGLFYPFLDDKEVAIIGVEAGGKGVNEKMEHCASLTGGRPGVLHGNRTYLLQDDDGQILEGFSISAGLDYPGIGPEHAWLHDIGRAKYVSITDAEALDAFQLCCETEGIIPALEPSHALAHVAKIAPDLPRDHIICMNMCGRGDKDIFTVAKALGQDMSGAV
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: LSM5_YEAST
Sequence: MSLPEILPLEVIDKTINQKVLIVLQSNREFEGTLVGFDDFVNVILEDAVEWLIDPEDESRNEKVMQHHGRMLLSGNNIAILVPGGKKTPTEAL
What is the function of this protein?
Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner.  Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation by activating the decapping step.  Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs.  LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 snRNP, U4/U6. U5 snRNP, and free U6 snRNP).  It binds directly to the U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes.  It probably also is involved in degradation of nuclear pre-mRNA by targeting them for decapping.  LSM5 binds specifically to the 3'-terminal U-tract of U6 snRNA.  LSM2-LSM8 probably is involved in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.  LSM5, probably in a complex that contains LSM2-LSM7 but not LSM1 or LSM8, associates with the precursor of the RNA component of RNase P (pre-P RNA) and may be involved in maturing pre-P RNA.  LSM5 is required for processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.
What are the official names of this protein?
U6 snRNA-associated Sm-like protein LSm5.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYS_YERPG
Sequence: MLDPNMLRNELDAVAEKLARRGFKLDVEVLRQQEERRKVLQVETESLQAERNSRSKQIGAAKARGEDIEPLRLEVNALGEKLDAAKAELDKLQNEIRDLALSIPNLPDDSVPVGKNENDNIEVSRWGEPRKYDFDVKDHVSLGEMAGGLDFAAAVKLTGARFVVMKGQIARMHRALSQFMLDLHTEKHGYLEAYVPYLVNHATLYGTGQLPKFGEDLFHTKPLAEESDNSNYALIPTAEVPLTNLVRDEILEEDSLPLKLTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQITRPEDSMAALEELTGHAEKVLQLLELPYRKVLLCTGDMGFGSSKTYDLEVWLPAQDTYREISSCSNMWDFQARRMQARYRNKTDRKTRLVHTLNGSGLAVGRTLVAVLENYQQADGRIQVPDVLRPYMGGLEYIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNT_SERP5
Sequence: MKALKGSWAILLAIFFALVYLIPLNGRLLWQPDETRYAEISREMLQRGDWVVPHLLGLRYFEKPVAGYWFNNISQWLFGDTNFAVRFGSVFSTGMTALLVFALAMLMWRNARRASLATLIFLSMVLVFSIGTYSVLDPMISLWLAAAMVSYYLTLKATTAKGKLGGYVLLGLACGMGFMTKGFLALAVPVIAVIPIVIQQRRIKDLLIYGPVAIVVAVLLSLPWALAIAQREPDFWNYFFWVEHIQRFAEDNAQHKAPFWYYVPVLMAAVLPWLALLPGSLLKGWRERVQRPELFFLLSWVMMPLIFFSIAKGKLPTYILPCMAPLALLMAAYAEDCVAALRSKVFKVNAVLNGLFGLICILALVVLGSGLLPKVHLFTAQEWPKIVIGIIAFAGWLLFAVVSVRNNAQRWSWAAACPLLLCLLIGYAIPQQVTDSKLPQNFIRVNMAELGHSRYVLTDSVGVAAGLAWELKRSDVLMFNQKGEVSYGLEYPDARSHLISDSDFPQWLAQARKQGDVSLVLQLSRGESIDQQKLPKADKVEVMNRLALFWYQQQP
What is the function of this protein?
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase, 4-amino-4-deoxy-L-arabinose lipid A transferase, Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase, Undecaprenyl phosphate-alpha-L-Ara4N transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 83 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KHSE_GLOVI
Sequence: MCVRVPATSANLGPGFDCLGVALDLANEFEFCEADRFRCVVHSTVSPEDARQVATDERNLAWRAFTHLFEHLGKTPPTVALTVMMHVPLGRGLGSSATAIVGGIAAANRWLGSPLSTPEWLLLASRLEGHPDNVVPAALGGCQLSILGETLLTCALDWHPQIALVLAVPDFALATSKARAALPKTVPHTDAVFNAVHLALLVRALATGDARWLAEALQDRLHQPYRTGLIPGWQDVRAAALEAGAWGVVISGAGPSVLALTHLDCAEAVRQAMASTWPNACLYCPGLDPNGCRVEVEAG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BBLA_TOBAC
Sequence: MFPLIILISFSLASLSETATGAVTNLSACLINHNVHNFSIYPTSRNYFNLLHFSLQNLRFAAPFMPKPTFIILPSSKEELVSTIFCCRKASYEIRVRCGGHSYEGTSYVSFDASPFVIVDLMKLDDVSVDLDSETAWAQGGATIGQIYYAIAKVSDVHAFSAGSGPTVGSGGHISGGGFGLLSRKFGLAADNVVDALLIDADGRLLDRKAMGEDVFWAIRGGGGGNWGIVYAWKIRLLKVPKIVTTCMIYRPGSKQYVAQILEKWQIVTPNLVDDFTLGVLLRPADLPADMKYGNTTPIEIFPQFNALYLGPKTEVLSISNETFPELGVKNDECKEMTWVESALFFSELADVNGNSTGDISRLKERYMDGKGFFKGKTDYVKKPVSMDGMLTFLVELEKNPKGYLVFDPYGGAMDKISDQAIAFPHRKGNLFAIQYLAQWNEEDDYMSDVYMEWIRGFYNTMTPFVSSSPRGAYINYLDMDLGVNMVDDYLLRNASSSSPSSSVDAVERARAWGEMYFLHNYDRLVKAKTQIDPLNVFRHEQSIPPMLGSTQEHKYSSE
What is the function of this protein?
Involved in the biosynthesis of pyridine alkaloid natural products, leading mainly to the production of anabasine, anatabine, nicotine and nornicotine, effective deterrents against herbivores with antiparasitic and pesticide properties (neurotoxins); nornicotine serves as the precursor in the synthesis of the carcinogen compound N'-nitrosonornicotine (NNN) (PubMed:21343426).  Catalyzes a late oxidation step subsequent to the pyridine ring condensation reaction in the biosynthesis of alkaloids (PubMed:21343426).
What are the official names of this protein?
Berberine bridge enzyme-like A, NtBBLa.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
What are the subcellular locations of this protein?
Vacuole.
Protein: CYSN_ECOL6
Sequence: MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIHYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGDK
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: EFTS_PLAVS
Sequence: MKLHTLVMFTLVIGSPLLPQHRCYRNSQTFQLVHTLNKFVGRRRRALKPTLHANPPSEHLQNLKYVREVTNASIQICNDALKECKGDVEKAIELVRRSAKNSSFVSTSVKVKTEGLVGSQVGGDQVVMLEVLTDSDFVARNEKFVRFVRTLLGAALAGGAAHGGAVTGEGSGATALLSLPYDEQSGGSHSGGPHIAHSTTTVGEQMNYLRNIFREDVRIGRFARYERKNANQFLHCYIHNRVEENIGTSGVLLVLTIDELSEKLKSQGECIAEVANDMALHILSAKPVSVSVSDLPEQVVKREVAIIRESLRGVKKPEGILDSMVNGKMRKFYSSVVLLEQEYMLDDTKRKVSQVIRDFCKKHNLNISVRHFDTFIVGEKNILREGPMGG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, mitochondrial, EF-Ts, EF-TsMt.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ISPH_BORPE
Sequence: MTAEVTAADAEVLLAQPRGFCAGVDRAIDIVERALELHGAPIYVRHEIVHNRYVVEDLRGKGAVFIDELDQAPAGAIVVFSAHGVSQAVRGEAEARGLRVFDATCPLVTKVHIEVARMRAAGREIVMIGHKGHPEVEGTLGQAQGGMYLVETVEDVAALQVSDPGNLAYVTQTTLSVDDAAAVAGALKARFPGIVEPKKSDICYATQNRQDAVKLLAPECDLVLVVGSTNSSNSNRLREVAERKGVAAYLIDGAHAIDPAWLQGRRSIGITAGASAPEVLVQQVVERVRELGAVSVRTMPGLEESVAFPLPKGLSRKIAQTESLE
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: PDXT_BACCQ
Sequence: MVKIGVLGLQGAVREHVKSVEASGAEAVVVKRIEQLEEIDGLILPGGESTTMRRLIDKYAFMEPLRTFAKSGKPMFGTCAGMILLAKTLIGYDEAHIGAMDITVERNAFGRQKDSFEAALSIKGVGEDFVGVFIRAPYVVNVADNVEVLSTHGDRMVAVRQGPFLAASFHPELTDDHRVTAYFVEMVKEAKMKKVV
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: DAPF_RHOE4
Sequence: MATMDFSKGHGTQNDFVVLPDLDVRVDLEPARVSALCDRQRGLGADGILRVARAGALADAGVLGALPDGVAAEDWFMDYRNSDGSIAEMCGNGVRVFAHYLKASGLESKDEFVVGSRAGARPVVVHGYDATHGDVTVAMGPIKDLGTSSATIDGRVFAGVGIDVGNPHLACVDEHVTAEVLSALDLSVSPGFDPGFFPHGVNIEIVTPIHDGGVHMRVHERGVGETRSCGTGTVAAAAAALKFDGRDEGSVLVRVLGGEVQVTVEGGEGSLRGPSVLVANGTISDAWWQSLV
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADD_HAEDU
Sequence: MVLGLAQYGVIDLHLHLDGSLSPAWMIEWAKKQAVNLPASTAEALTAYVSVPQDCSDLNEYLRCFDLPLSLLQTPEALSSAVTDLIQRLDQDGLVYAEIRFAPQLHTQRSMSQEDAVKAALRGLQAGLASTSLFKANLILCCMRAADNRSANLETICLAKQYLTKYEAGVVAIDLAGAEGLFATQHFQQEFDFANQRGVPFTIHAGEAAGPESVQQALDFGATRIGHGIRAIESETVMKQLIDKRTPLEMCPCSNLQTKTVAQLADYPLRTFLMRGVVATLNTDNMTVSQTCIQQEYRLLAEQYQLSISEAKQLLLNSIAAAFLSNEDKKALLAHIQQRYPQLI
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: SYGB_GEOUR
Sequence: MTKELFLEIGTEEIPAGFLPKAMAEMEGLIRKELDNARIAFGEVKAMATPRRLALVVSQVAGQQADAEITAMGPAKKVAFNEDGTPTRAGEGFARGQGVEPSALSIVVTEKGEYVAVTKKETGVPTVGLLGEILPRLINNISFKKSMRWGDLDVRFARPVHWIVALFDGIVVPFSFGNIESGTMSRGHRFMANTSFPVRDFTHYLDECERHFVIPDPAKRKEIIRREIHRVAKAAGGRLLPDEGLLEQVTYLVEYPSAVHGTFSAEFLVVPREVLITSMREHQRYFSLVDDNGKLLPGFITINNTLTEDPSVVVKGNERVLRARLSDARFFFDEDKKVPLENRVESLKSVLYQAKLGTSYEKMERFRALAEGVAEELQPGLKEKVSQAATLCKADLVTGMVGEFPEVQGIMGREYAFLQGIDPGVANAIAEHYLPTQAGGELPASDIGAFVSIADKLDTICGCFSVGLIPTGSADPYALRRAALGIINIIVAKGYALQLTTLVSKALARLEGKLTRKKEEVFGDVMDFFQGRFVNLMTDRFPADVVDAVVAVSFDDLVDTAAKIEALAVFKKRPDFEPLAVAFKRVCNIVKGPVVVVGVNELDFEEDAEGTLHRAYHSVAGTVAAKVAERDYLAALTQIATLKGAVDDFFDNVMVMAEDERVRNNRLALLQEIKGLFRDIADFAKITA
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_XYLFA
Sequence: MGRHYEIVLLVHPDQSEQVQAMLERYKALIENGHGKIHRLEDWGRRQLAYPIQKLVKAHYLMMNIEVEQSVLNELVDLFRFNDAILRHLAIKRSGPDTEQSFIMKSKDDKGDKPERRRRDDDENGDVGVSNDSDNDGGNAEAA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: RR12_NICTO
Sequence: MPTIKQLIRNTRQPIRNVTKSPALRGCPQRRGTCTRVYTITPKKPNSALRKVARVRLTSGFEITAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGTLDAVGVKDRQQGRSKYGVKKPK
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RFU1_YEAS7
Sequence: MKSSKQLVQDAKDYRFNPAIPLRIYLKTCIGILEKAQCAFQANDLSLSFIYYFRYVDLLTNKLSRHPELLRMDASSSSSSSYIHKREYLQLIKLEVPAVCKIIESLRTQIDSQYSKLQTSLANNIAKPNINANTTPVQVEQQPLPKKSFDEYSFNQSISFFQKISNAQLNTGASSQSQATARDEAYRLNYPELPRLTFST
What is the function of this protein?
Inhibitor of the DOA4 deubiquitinase involved in the regulation of protein degradation by the proteasome and maintenance of a normal level of free ubiquitin.
What are the official names of this protein?
Regulator of free ubiquitin chains 1.
What is the protein family that this protein belongs to?
Belongs to the RFU1 family.
What are the subcellular locations of this protein?
Endosome.
Protein: NAA20_XENLA
Sequence: MTTLRAFTCDDLFRFNNINLDPLTETYGIPFYLQYLAHWPEYFIVAEAPGGELMGYIMGKAEGSVAREEWHGHVTALSVAPEFRRLGLAAKLMELLEEISERKGGFFVDLFVRVSNQVAVNMYKQLGYSVYRTVIEYYSASNGEPDEDAYDMRKALSRDTEKKSIVPLPHPVRPEDIE
What is the function of this protein?
Catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln.  Proteins with cell cycle functions are overrepresented in the pool of NatB substrates.  Required for maintaining the structure and function of actomyosin fibers and for proper cellular migration.
What are the official names of this protein?
N-alpha-acetyltransferase 20, Methionine N-acetyltransferase, N-acetyltransferase 5, N-terminal acetyltransferase B complex catalytic subunit NAA20, N-terminal acetyltransferase B complex catalytic subunit NAT5, NatB complex subunit NAT5, NatB catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ARD1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ELYS_HALCR
Sequence: MKLLVLCVFAMMATLAVSRRYQFVQHQYIRKAFEVALKVEIIAGFDRTLVKWLRNHGRGLNENQRKVLYFVNRRYMQTHWQNYMLWIVKKTNALGRPPVVADYRALGAEIGRRIDMGYFYNFLKNRVMIPKYLPYMRRLNNMRPEDVPVANRNPGK
What is the function of this protein?
Creates a 3 um hole in the egg vitelline layer through which the sperm passes.  Does not have enzyme activity.  Species-specific interaction between the sperm protein lysin and the egg protein VERL exposes a basic surface on lysin that may dissociate the egg vitelline layer via electrostatic repulsion.  Plays a role in ensuring species-specific fertilization.
What are the official names of this protein?
Egg-lysin, Sperm-lysin.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome lumen.
Protein: MYG_CTEGU
Sequence: MGLSDGEWQLVLNAWGKVETDIGGHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKASEDLKKHGTTVLTALGNILKKKGQHEAELAPLAQSHATKHKIPVKYLEFISEAIIQVLESKHPGDFGADAQGAMSKALELFRNDIAAKYKELGFQG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: MURA_COXB2
Sequence: MDKLIIVGGVPLNGSIRISGAKNAVLPILAATLLIEEPVILSNIPHLNDVTTMIELLGRMGAQITIDERMSIEVDCSQIQNVHASYELVKTMRASILVLGPLLSRFGKAEVSLPGGCAIGSRPVDVHIDGMRALGADIELVDGFIHATVEGRLKGAELNLGKITVTGTENLIMAATLAEGQTIIHNAACEPEVQDLANFLNKMGARISGAGTDTIVIDGVDRLSGGSYSILPDRIEAGTYLVAAAMTRGHVRIRDVFPKTLGAVLEKLHEAGARVKIGENWVDLDMQGRRAKAVDIVTAPYPEMPTDMQAQFMALNVVAEGQAVITETVFENRFMHVHELQRMGADIKLQGSKALIRGKEKLTGAPVMATDLRASAGLVLAGLMARGNTIVDRIYHIDRGYECIEEKLAQLGAEIRRVSSHVYAARYAAQKRWL
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLIC5_MOUSE
Sequence: MTDSATTNGDDRDPEIELFVKAGIDGESIGNCPFSQRLFMILWLKGVVFNVTTVDLKRKPADLHNLAPGTHPPFLTFNGDVKTDVNKIEEFLEETLTPEKYPKLAAKHRESNTAGIDIFSKFSAYIKNTKQQNNAALERGLTKALRKLDDYLNSPLPEEIDTNTHGDEKGSQRKFLDGDELTLADCNLLPKLHVVKIVAKKYRNYDIPAEMTGLWRYLKNAYARDEFTNTCAADSEIELAYADVARRLSRS
What is the function of this protein?
Required for normal hearing (By similarity).  It is necessary for the formation of stereocilia in the inner ear and normal development of the organ of Corti.  Can insert into membranes and form poorly selective ion channels that may also transport chloride ions.  May play a role in the regulation of transepithelial ion absorption and secretion.  Is required for the development and/or maintenance of the proper glomerular endothelial cell and podocyte architecture (PubMed:17021174).  Plays a role in formation of the lens suture in the eye, which is important for normal optical properties of the lens (PubMed:29425878).
What are the official names of this protein?
Chloride intracellular channel protein 5.
What is the protein family that this protein belongs to?
Belongs to the chloride channel CLIC family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Membrane; Single-pass membrane protein. Apical cell membrane; Single-pass membrane protein. Cytoplasm. Note=Colocalized with AKAP9 at the Golgi apparatus as well as, to a lesser extent, the centrosome (By similarity). Associates with the cortical actin cytoskeleton (By similarity). Localizes to the apical region of cochlear hair cells, at the base of the actin-rich hair bundle (PubMed:17021174). Colocalizes with podocalyxin at the apical cell membrane in renal glomeruli (By similarity). May localize to the centrosome in lens epithelial cells (PubMed:29425878). Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain (By similarity).
Protein: SYC_METCA
Sequence: MLKIYNSLTRQKEEFRPLEPRRVRMYVCGMTVYDYCHLGHARVMVVFDMVARYLRHLGLKVTYVRNVTDIDDKIIRRAVENGETIGALTARFIEAMHEDERALGVLPPDHEPRATESIDDILAMIGTLIERGHAYVGSNGDVFYAVASFPNYGRLSGKNLDELRAGERIEVDEAKRDPLDFVLWKSAKPGEPFWASPWGPGRPGWHIECSAMSTRCLGAHFDIHGGGMDLQFPHHENEIAQSEGATGEHFVNYWMHNGFVRINEEKMSKSLGNFFTVREILARYRPEVVRFFILNSHYRSPLNYSDENLDEAAAALSRLYTALRGLAPDLPLPLGEDRDEGFSSRFADAMQDDFNTPEAIAVLFDLAREINRHKAAEPAKAAALGATLKSLGNVLGLLQTDPEAYFKSDAGGSGLSDADIETRIRARLEARKAKNWAESDRIRDELKAQGIILEDSAAGTTWRRE
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OAT_EMENI
Sequence: MTSNGTNGSATAYHASSTQEAIQAENDFAAHNYHPLPVVFARAQGTSVWDPEGRHYLDFLSAYSAVNQGHCHPKLVAALVDQASRLTLSSRAFYNDVFPKFAEMVTKYFGFDMVLPMNTGAEAVETGIKIARKWGYKVKGIPENEAIILSAENNFHGRTMAAISLSSDPESRENYGPYVPNIGCTIPGTEKPITYNDKAALREAFEKAGSNLAAFLVEPIQGEAGIIVPDDDYLQLARSLCDQHNVLLICDEIQTGIARTGKLLCHEWSGIKPDMVLLGKAISGGMYPVSCVLGRKDVMLTVEPGTHGSTYGGNPLACAVAIRALEVVQEENMVERAEKLGQAFRSGLEAIQNPIIQTVRGKGLLNAIVIDESKTNGHTAWDLCMLMKEKGLLAKPTHQNIIRLAPPLVITEEEIAKALEIIKAAVAELPNLKGAAEDKVVPPPEKKVKITLEN
What are the official names of this protein?
Ornithine aminotransferase, Ornithine--oxo-acid aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOG1_NEOFI
Sequence: MAEFVRAQIFGTTFEITSRYTDLQPVGMGAFGLVCSARDQLTGQPVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENIISLSDIFISPLEDIYFVTELLGTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGVVHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVKSLPKRERQPLANKFKNADPEAVDLLERMLVFDPKKRIRAGEALAHEYLTPYHDPTDEPEAEEKFDWSFNDADLPVDTWKIMMYSEILDFHNIDQGNDAGQVLMEGGVAQAHQNYA
What is the function of this protein?
Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment.  Controls osmotic regulation of transcription of target genes (By similarity).
What are the official names of this protein?
Mitogen-activated protein kinase hog1, MAP kinase hog1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ENO_MYCTF
Sequence: MPIIEQVRAREILDSRGNPTVEVEVALIDGTFARAAVPSGASTGEHEAVELRDGGDRYGGKGVQKAVQAVLDEIGPAVIGLNADDQRLVDQALVDLDGTPDKSRLGGNAILGVSLAVAKAAADSAELPLFRYVGGPNAHILPVPMMNILNGGAHADTAVDIQEFMVAPIGAPSFVEALRWGAEVYHALKSVLKKEGLSTGLGDEGGFAPDVAGTTAALDLISRAIESAGLRPGADVALALDAAATEFFTDGTGYVFEGTTRTADQMTEFYAGLLGAYPLVSIEDPLSEDDWDGWAALTASIGDRVQIVGDDIFVTNPERLEEGIERGVANALLVKVNQIGTLTETLDAVTLAHHGGYRTMISHRSGETEDTMIADLAVAIGSGQIKTGAPARSERVAKYNQLLRIEEALGDAARYAGDLAFPRFACETK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RL17_GEOSM
Sequence: MRHNSAGRRLGRTTSHRIAMFRNMVTSFLQHEKITTTDAKAKELRSIAEKMITLGKRGDLHATRQAAAYIRDKKVVTKLFTEIAPRYTERPGGYTRIIKLGIRPGDNAPVSVLELVEAEMKPKKAAAKPAKAPKAAKAAPVAAAAAEEAPVAEAPVAEAPAAEETTEA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.