PharMolix/UniProtQA huggingface dataset:
Protein: LEPA_TERTT
Sequence: MSDLSHIRNFSIIAHIDHGKSTLADRFIQHCGGLSDREMAEQVLDSMELERERGITIKAQSVTLNYQARDGKTYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAAQGVEAQSVANCYTAIEQGLEVIPVLNKMDLPQAEPDKVAQEVEDIIGIDATEAVRCSAKSGLGIEDVLEALVNGIPAPVGDIDAPLQALIIDSWFDNYLGVVSLVRVTQGTLKTKDKIISKSIGKAHVVDMVGVFTPKRHVTGVLRAGEVGFVVAGIKEILGAPVGDTITHSNTADVKALPGFQKVKPQVYAGLFPVSSDDYESFREALAKLTLNDASLFYEPESSDALGFGFRCGFLGMLHMEIIQERLEREYDLDLITTAPTVVYEVVTSDGTTIYVDNPSKLPDVGFIDEMREPICEANILVPSDYLGAVITLCVEKRGIQKNLQYVGSQVSVSYELPMNEVVMDFFDRLKSVSRGFASLDYNFVRFEAAKLVRLDVLINSEKVDALALIVHRDNAPYKGRALADKMKELIPRQMFDVAIQAAIGGQIVARTTVKALRKNVTAKCYGGDVTRKKKLLEKQKAGKKRMKQVGRVEIPQEAFLAVLKVDS
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GRXC2_ORYSJ
Sequence: MAERVARLSSQRAVVIFGASNCFMCHVVKTLFSELGVSWAVHEVDKDPNGKDVERALAGMVGRTPPVPAVFIGGKLVGPTDQVMSLHLAGKLVPLLREAGALWLRDTKYSYILPANQLINYRSIN
What is the function of this protein?
Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase.  Reduces low molecular weight disulfides and proteins (By similarity).
What are the official names of this protein?
Putative glutaredoxin-C2.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. CC-type subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEP3_THUOR
Sequence: INVPLTRHKSMRESLREKGIELPYQDPAIKYRPEFATANYMYINQYADTIYYGAISIGTP
What are the official names of this protein?
Pepsin-3.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
Protein: CH60_MAGSA
Sequence: MAAKEVKFSTDARTRMLRGVDILADAVKVTLGPKGRNVVIEKSFGAPRITKDGVTVAKEIELADKFENMGAQMVREVASKTADLAGDGTTTATVLAQAIVREGVKAVAAGLNPMDLKRGVDLAVAAVVADVKSRSRKVATNAEIAQVGTISANGEKEIGDMIAKAMEKVGNEGVITVEEAKGLDTELDVVEGMQFDRGYTSPYFVTNAEKMTVELDNPYILLHEKKLSGLQPLLPVLEQVVQSGRPLVIIAEDIEGEALATLVVNKLRGGLKVAAVKAPGFGDRRKAMLEDIAILTGGQVISEDLGIKLESVNLEMLGTSKRITITKEDTTIVDGSGDKGAIDARCKQIRAQVEETTSDYDREKLQERLAKLAGGVAVIKVGGGSEIEVKERKDRVDDALHATRAAVEEGIVPGGGVALLHAVKALEGLASGNADQEVGISIVRRALQAPVRQIAENAGHDGAVVAGKIGESKDLSFGFDAQTGIYTDMIKAGIIDPTKVVRTALQDAASVAGLLITTEAMIAERPKKDAGGMPGGDMGGMGGMGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPX_STRZP
Sequence: MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLVIALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFIIDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAVALASAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLVQLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKGGGFQKLFYTHPPISERIERLKQM
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CF300_PARTE
Sequence: MQIESDNQVTNQSYSFFRQENTILDDKKFMEILQKWGLQHSIKVSTFLFDIKFDHLNPNQFLLDLFNSKDVRGSLHYVSFKQNVLLSQIKFQPLTCKSIKLDLFDKLTEDKIVVKGHIKQCFEEQFENIQIADELRKALVLEDSEQYCVFNEADRQELLFKLFQILVLGGQLCQYEDEIQAYLDWTKYLYKNTVNARKYADKDEIYIDSYAYDIRKLENSYSSDHPQNVMYVVVNPSLRIVNIIENQWLKVW
What is the function of this protein?
Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility.  Plays a role in outer and inner axonemal dynein arm assembly.
What are the official names of this protein?
Cilia- and flagella-associated protein 300.
What is the protein family that this protein belongs to?
Belongs to the CFAP300 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, cilium axoneme. Note=Localizes predominantly in the cytoplasm and weakly in cilia. Transported within cilia in an intraflagellar transport (IFT)-dependent manner. Accumulates at the ciliary tips during ciliogenesis.
Protein: RCF1_ASPFU
Sequence: MLNEPLPSSMEDNPQFKEETSLQKFRRRLKEEPLIPLGCAATCYALYRAYRSMKAGDSVEMNKMFRARIYAQFFTLVAVVAGGMYYKTERQQRREFEKMVEQRKAQEKRDAWLRELEIRDKEDKDWRERHAAIEAAAKEAGKRPAPKKLPEQDAARSAIEPADERSIGVLSAVRDLWMQQK
What is the function of this protein?
Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
What are the official names of this protein?
Respiratory supercomplex factor 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RCF1 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: SUFE_ECOL5
Sequence: MALLPDKEKLLRNFLRCANWEEKYLYIIELGQRLPELRDEDKSPQNSIQGCQSQVWIVMRQNAQGIIELQGDSDAAIVKGLIAVVIILYDQMTPQDIVNFDVRPWFEKMALTQHLTPSRSQGLEAMIRAIRAKAAALS
What is the function of this protein?
Participates in cysteine desulfuration mediated by SufS.  Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.
What are the official names of this protein?
Cysteine desulfuration protein SufE.
What is the protein family that this protein belongs to?
Belongs to the SufE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAP21_ASPFC
Sequence: MGSKSPEGHRQAPHASNCNELKPANPDPQISQNGSGSADLDRGVIGDDDDDEDAEENGVNTETPNVGKLNQPPFPNLDQVHVTTTDGLCITEKKKKRKKSNKKKKKTKSGALPATELKQTSPPRVLVSTLFPSEYPVGELVPYDCTARTTDEELRYNSRLWDDDFLPDYRQAAEIHRQVRQYAQKELIKPGATLLSIAEGIEDGVRALSGHQGLEPGDFFKAGMGFPTGLCLNHIAAHWTPNPREKDVILDKGDVLKVDFGVHVNGRIVDSAFTVAFDDKYDNLLTAVREATNTGIKHAGVDARMSDIGAAIQEVMESYEVEIDGKVFPVKAIRNITGHDILRYHIHGGKQIPFIKNNNQDKMEEGEVYAIETFGSTGRGFLDDDVGVYGYGRNENMSGANLRLSSAKSLLKTIDASFGSIVFSRRYLERLGVKNYLLGMKNLIDNGIVECYSPLVDVKGSYTAQFEHTILLHSGGKEVISRGDDY
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase 2-1, MAP 2-1, MetAP 2-1, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HDOX_STAS1
Sequence: MYVVTNRIDVKKGFAEKMAPKFTQGGKIQELEGFQKVEVWLIDDEADYDQMYINTWWDSEDDFKGWLKSDAFKEAHEGKSKTKSDDSPILGNKVVKANVISELS
What is the function of this protein?
Allows bacterial pathogens to use the host heme as an iron source.  Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.
What are the official names of this protein?
Heme oxygenase (staphylobilin-producing), Heme-degrading monooxygenase, Iron-regulated surface determinant, Iron-responsive surface determinant.
What is the protein family that this protein belongs to?
Belongs to the antibiotic biosynthesis monooxygenase family. Heme-degrading monooxygenase IsdG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1054_BACMK
Sequence: MVHMHITAWALGLILFFVAYSLYSAGRKGKGVHMGLRLMYIIIIVTGFMLYMSIVKTATGSMHMWYGMKMLAGILVIAGMEMVLVKMSKNKPTGAVWGLFIVALVAVLYLGLKLPLGWYVFK
What are the official names of this protein?
UPF0344 protein BcerKBAB4_1054.
What is the protein family that this protein belongs to?
Belongs to the UPF0344 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TPIS_BACC7
Sequence: MRKPIIAGNWKMNKTLSEAVSFVEEVKGQIPAASAVDAVVCSPALFLERLVAATEGTDLQVGAQNMHFEKNGAFTGEISPVALSDLKVGYVVLGHSERREMFAETDESVNKKTIAAFEHGLTPIVCCGETLEERESGKTFDLVAGQVTKALAGLTEEQVKATVIAYEPIWAIGTGKSSSSADANEVCAHIRKVVAEAVSPAAAEAVRIQYGGSVKPENIKEYMAQSDIDGALVGGASLEPASFLGLLGAVK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSY_ANAPZ
Sequence: MFIAILMGAYLLGSIPFAYILTKLMAKRDIREVGSKNVGATNVFRVNKGLAGLVLLLDIAKSAVLIYSLKEYDIVSTKEELCIVGLLSVLGHIYPIWLKFKGGKGVATGIGVIIPLNPLMLCVFFISWLFTFNNTRYASLSSIVSIIATMIVCYLTESGVVALLYTVQSILILFKHRENIVRLIKREEKKVI
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL20_WOLPM
Sequence: MARVKRGVTTHARHKKILKLAKGYRGRAKSCYRIALQRVEKALQYAYRDRRTRKRDFRSLWIIRINAAAREHGLTYGRFMHGLTLAGIDLNRKILAEMAVNYKDDFAKLVETVSGKLAESS
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ATP6_SALEP
Sequence: MASENMTPQEYIGHHLNNLQLDLRTFSLVDPQNPPATFWTLNIDSMFFSVVLGLLFLVMFRSVAKKATSGVPGKFQTAIELIVGFVHGSVKDMYHGKSKLIAPLALTIFVWVFLMNLMDLLPIDLLPYIAEHWLGLPATRVVPSADVNITLSMALGVFILILFYSIKMKGIGGFAKELTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1824_YERPG
Sequence: MTIKPSDSVSWFQVLQRGQHYMKTWPADKRLAPVFPENRVTVVTRFGIRFMPPLAIFTLTWQIALGGQLGPAIATALFACGLPLQGLWWLGKRAITPLPPTLLQWFHEVRHKLFEAGQAVAPIEPIPTYQSLADLLKRAFKQLDKTFLDDL
What are the official names of this protein?
UPF0208 membrane protein YpAngola_A1824.
What is the protein family that this protein belongs to?
Belongs to the UPF0208 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VIP_RAT
Sequence: MESRSKPQFLAILTLFSVLFSQSLAWPLYGPPSSVRLDDRLQFEGAGDPDQVSLKADSDILQNALAENDTPYYDVSRNARHADGVFTSDYSRLLGQISAKKYLESLIGKRISSSISEDPVPVKRHSDAVFTDNYTRLRKQMAVKKYLNSILNGKRSSEGDSPDFLEELEK
What is the function of this protein?
PHM-27 is a potent agonist of the calcitonin receptor CALCR, with similar efficacy as calcitonin (By similarity).  PHI also causes vasodilation.
What are the official names of this protein?
VIP peptides.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y8591_DICDI
Sequence: METQTSFINDGPKIHSNKLNQLDFLSGNNNNNRDNYYNNKNDKNSITHFNNYNYSGHSSYDNESARLIPISGNFKNESINKQRRKVVIARIFILLCLLICLGLALMGLFHYLITNDKRLDSISILFWSGSAFLIIVLIICLLARHCGSD
What are the official names of this protein?
Putative uncharacterized protein DDB_G0289825.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PSA73_DROME
Sequence: MAQRYDRAVTIYSPDGHLLQVEYAQEAVRRGSTVMGLRTNNAIVIGVEKRSVGDLQEERMVRKICMLDDHVVMTFSGLTADARILVSRAQMEAQSHRLNFEKPTTVEYITRYIAQLKQNYTQSNGRRPFGLSCLVGGFDEDGTPHLFQTDPSGIFYEWRANTTGRSSQPVRDYMEKHADEILTIADEAAAIKHIVRTLVSVSSLNHTQMEVAVLKYRQPLRMIDHQVLADLERTVRREIEDEAEASRRPRAP
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit alpha type-7-1B, Testis-specific alpha4-t2 proteasome subunit, Testis-specific proteasome 28 kDa subunit 1B.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PYRB_KLEP3
Sequence: MANPLYQKHIISINDLSREDLELVLATAAKLKANPQPELLKHKVIASCFFEASTRTRLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDAIVMRHPQEGAARLATEFSGGVPVLNAGDGANQHPTQTLLDLFTIQETQGRLENLNVAMVGDLKYGRTVHSLTQALAKFSGNRFYFIAPDALAMPQYILDMLDEKGIAWSLHSAIDDVMAEVDILYMTRVQKERLDPSEYANVKAQFVLRAADLEGARANMKVLHPLPRIDEITTDVDKTPHAWYFQQAGNGIFARQALLALVLNSELAL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RL5_CAMHC
Sequence: MNRLKQLYENSIKPAIVKEFDIKNSMLIPKLDKIVISVGVGESSKDEKILQNMADTISLIAGQKAVITNAKKSIAGFKVREGFPVGIKVTLRKDNMFVFLDKLVSIALPRVKDFRGLSRDGFDGRGNYNFGLDEQLMFPEVEYDKILKTHGMNITIVTTANSDKEAFKLLELFGVPFAKGK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: MNMA_DESOH
Sequence: MPLMNPLNPWPLESSNPLIAVLVSGGIDSLVAAHLLKQSGADVTAIHFLTGYEPEDRAGRLEKLFTQMDIPVFIFDCRTVFQSNVVDYFTAAYLRGETPNPCMVCNSRIKFGACMDYARSLGADAVATGHYCRTTKDPDGVRLWKGADPAKEQSYFLAFLSQDQLGRARFPLERMTKDQVRAHAARHGLVPIESKESQDVCFIRGEECADFIEAQVPAIPGPGPIEDMTGRLIGTHSGLHRFTVGQRRGINCPAEQPYYVAALDMARNCLKVGFRQDLFVPVCRVAQVNWIPDRPKGSMNVSVKIRYNQTEVPARLTALGETDAVVEFVTPQFAVAPGQGAVFYDGDAVLGGGIIRAE
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTF18_XENLA
Sequence: MEEYDLYGVEDDFESQFASELEVLAELEDDVSSRPGPQRSQLRTKLSFEEAISAGDPIRSNANSKPTGDSNGEALACIDTSKSKKRDASCIDFEEDEFSDSIYEPPITPKHKRARIEAVKKLDFGRDEYAGNSTALSDDITPPPSPNHSPKKNERDSKFSSCEAFEVSDMAPLQVTPTESEQKRVLKRPPVLEDYINVTSTDGSRVYMALKEDNDGAQQKQGNLKWNSGQQLHLLGVPFSYLKEQVNDEHRRKVLEESQRLTEMLNSQINEEFGENDSEILENDDNAGEEDDEDEPSSHSLWVDRFTPRHYTELLSDDYTNRCLLKWLKLWDTVVFGKERVVRKPKAIVDPRANHFKNQKEQQSKFKTKAQITEEILEAELDHHNRPKNKVSLLCGPPGLGKTTLAHVIARHAGYNVVEMNASDDRSPEAFRTRIEAATQMKSVLGVDERPNCLIIDEIDGAPTVSINMLLSLVNRKDAKEAEGGTEATTGKKKKKEGGLLLRPIICICNDQYVPSLRQLRQQAFMLNFPQTMPSRLVQRLYEIAVKQGMKADTGALMALCEKTENDIRSCINTLQFLHGRGKKELNMRSVQTMRIGLKDQNKGLFSVWQEIFQLPKIQRKRIGQEVATNDLHLLLGSENDSLGMLAKPPLNAVAQRFHHILHLSTSTGEYEKLTMGLYDNFLNMKVKESNFSTVCLALDWLEFTDIVNSTIMHGQNFQLMRYLPFLPVAFHLLFAASNVPRIAYPSSHYEAQSKLNQMQNLLNAMVSEISPAIRTRVGPQSLVLDALCLLLDVLSPKLRPVNTQLFSTKEKQQLAELINTMLAYNLTYHQERTMEGQYVYKLDPNVEDVCRFPDLPVRKPLTYQTKQLIAREIELERMRRTEAFQQARNAGRDNTTAAAAVKTADPKGAKSAAKPAALNHEQRLENIMKKATFEEKPEKDFFGRQIVKKVAAPVTASANQEESVERRIGKAVGNSDVWFRFNEGVSNAVRRNIYIKDLL
What is the function of this protein?
Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission.  Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of ctf18, ctf8, dcc1, rfc2, rfc3, rfc4 and rfc5.  The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated by the presence of primed DNA, replication protein A (RPA) and by proliferating cell nuclear antigen (pcna).  The CTF18-RFC complex catalyzes the ATP-dependent loading of pcna onto primed and gapped DNA (By similarity).
What are the official names of this protein?
Chromosome transmission fidelity protein 18 homolog.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. CTF18 subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Associates with chromatin during S phase.
Protein: DAPF_YERPS
Sequence: MQFSKMHGLGNDFMVVDAVTQNVYFSPELIRRLADRHTGVGFDQMLVVEPPYDPELDFHYRIFNADGSEVSQCGNGARCFARFVRLKGLTNKREISVSTQTGRMILSVTEDEQVCVNMGEPDFEPQTVPFRAAKAEKTYILRAAEHTVLCGVVSMGNPHCVMQVDDVSVANVALLGPVLENHERFPERANIGFMQVVSRDHIRLRVYERGAGETQACGSGACAAVAVGVVQDLLNENVHVELPGGSLHIRWQGPGHPLYMTGPATHVYDGFIHL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_BIFLS
Sequence: MSVAILGKGKKVALKRRHARIRKRISGTPERPRLVVTRSNRHMVAQVVDDTKGITLVSASTLQADFAGFEGTKTEAAKKVGELIAEKAKAAGITAVVFDRGGNKYTGRVAAVADGAREGGLAL
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: UL41A_HCMVM
Sequence: MTLFCRTANSTAGYVDMNVCIGMIGVVCFVFGVFILIFCSTLKAFYVRQKTYHLLGTESDDEETTVWEKRRMESDTDF
What are the official names of this protein?
Protein UL41A.
What is the protein family that this protein belongs to?
Belongs to the HHV-5 UL41A protein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein.
Protein: CD1B_AOTNA
Sequence: MLLLPFQLLAVLFPGGNSEHAFQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYILGFAREVQDFAGDFQMKYPFEIQGIAGCGLHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKVCALIMQYQGIMEIVRLLLYKTCPRYLLGVLNAGKADLQGKMKPEAWLSSGPSPGPGRLLLVCHVSGFCPKPVWVMWMPGEQEQQGTQLGDILPNANWTWYLRATLDVAAGEAAGLSCRVKHSSLEGQDIILYWSNPTSIGSIVLAIIVPSLLLLLCLALWYMRRRSYQNIP
What is the function of this protein?
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
What are the official names of this protein?
T-cell surface glycoprotein CD1b.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes.
Protein: GDNF_RAT
Sequence: MKLWDVVAVCLVLLHTASAFPLPAGKRLLEAPAEDHSLGHRRVPFALTSDSNMPEDYPDQFDDVMDFIQATIKRLKRSPDKQAAALPRRERNRQAAAASPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCEAAETMYDKILKNLSRSRRLTSDKVGQACCRPVAFDDDLSFLDDSLVYHILRKHSAKRCGCI
What is the function of this protein?
Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.  May also modulate local neuronal effects in distal regions of the motor neuron.
What are the official names of this protein?
Glial cell line-derived neurotrophic factor, Astrocyte-derived trophic factor, ATF.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family. GDNF subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: UPP_STRPG
Sequence: MGKCQVISHPLIQHKLSILRRQTTSTKDFRELVNEIAMLMGYEVSRDLPLEDVDIQTPVSKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGMYRNEETLEPVEYLVKLPEDINQRQIFLVDPMLATGGSAILAVDSLKKRGAANIKFVCLVAAPEGVKKLQEAHPDIDIFTAALDDHLNEHGYIVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: HSLV_BORBU
Sequence: MSFKGTTVIAIKKNGKTVVAADGQVTFGHTVLKSNAIKIRKLLNGKILAGFAGSTSDAITLFEKFEEKIKAKGDGLIDIKRAAVDLAKDWRSDKILHKLEAMMLVADSNNILLISGTGDVVEPEEDVISIGSGGNYAYSAALAYMENKKLSAFEVALRSLKIAARVCIYTNSNIVLEEIENE
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.