PharMolix/UniProtQA huggingface dataset:
Protein: RL31B_BDEBA
Sequence: MKQNLHPKVNTVVFKDISCDFSFLGTSTLHSSETVKWEDGKEYPLIKVEISSASHPFFTGKQRVMDTEGRIDRFKKRYGKK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: PSTB1_STRP1
Sequence: MTEPILQIRDLSVYYNQKKTLKDVSLDLYPNEITALIGPSGSGKSTLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSIYENVVYGLRLKGIRDKSILDHAVESSLKGASIWNEVKDRLHDSAVGLSGGQQQRVCIARVLATSPRIILLDEPTSALDPISAGKIEETLLLLKKDYTLAIVTRSMQQASRLSDRTGFFLEGDLLECGPTKAMFMNPKRKETEDYISGKFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 1, ABC phosphate transporter 1, Phosphate-transporting ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DAPA_CHLPB
Sequence: MSKRKLSGSAVALVTPFRQDMSVDREAIRRLVHFHIAAGTDILIPCGTTGESPTLTADEQTEIIEIVREEAGNKMLVAAGAGTNATEEAVSLASNAQKAGAQALLSVAPYYNKPSQEGYYQHYRRIAEAVSIPVIVYNVPGRTGSNVHAETILRLAHDCENIAAVKEASDNMAQIMELLASRPDDFSVMTGEDSLILPFMALGGDGVISVAANLLPAEVKQLVTEMHEGDLEKARVIHNRLRRLFSLNFIESNPVPVKYSLSLMGMIEEVYRLPLVALQPENKEKIKEELRNLGLVS
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: USP9_PINMG
Sequence: MQKLTIFVIFLCCWLVLTMADDYVKKCQHHCDLQLKRCARECHFPFHPYHKECLKICEKTKLHCFRWCAHA
What are the official names of this protein?
Uncharacterized shell protein 9, Nacre uncharacterized shell protein 10, NUSP10.
What are the subcellular locations of this protein?
Secreted.
Protein: FOLD_BURO0
Sequence: MTALLIDGNALSKTLRAQAAERAAALTARGHQPGLAVILVGANPASEVYVRNKIKACEDNGFFSLKDAYPATLSEADLLARIHELNRDPKIHGILVQLPLPAHIDSHKVIEAIAPEKDVDGFHVANAGALMTGKPLFRPCTPYGVMKMFEAHGIALQGANAVVIGRSNIVGKPMAMMLLDAGATVTICHSKTRDLAAHTREADIVVAAVGKRNILTADMVKPGATVIDVGMNRDDAGKLCGDVDFAGVKEVAGYITPVPGGVGPMTITMLLINTIESAERAAAAAA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RPOZ_THEM4
Sequence: MNPVINYDELLKKIPYKFAIPIAVAKRAENLKEFAHSYVETWDNNYVSIALKELSEGYIRIKNEEILKVLIPNVK
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: HRCA_MYCPN
Sequence: MKNLTTRQAQILKAIINEYIAYPVPVGSKLLTKKYFKNLSGGTLRNEMAVLEKEGYLKKNHISSGRIPSQLGYQYYVKLLTKNDDKSNLKTRLRAIILQKHKTIDEIIELGVKFINEMVNLPVVLTHFSSDEVLKKIDLIMLDQSCALLLLVSASGNVFKKTISYANQRQFEDIMVCVRIFNDRIIDTRFCDIAQHLDVLKEIIRSKVHEYQYVIDEILFKLFNFEEFQQARKQVYGIHYLAQQPEFANQERLTRILNLLEDTSVWQQMAFMNQNNQTTNITFGDKLGLEGEEVSVASTLINTTNESKHQLAIVGPTRMDYQKVKALLLTLKEEIEEYDKQLHGGKTTSST
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: DCDB_CYTH3
Sequence: MILSGLEIKDKLGSDIVIEPYDDSRLNPNSYNLRLHNELLVYDNNELDMKKPNTASPLIIPEEGLLLETGKLYLGRTIEYTESHNYVPMLEGRSSIGRLGLFVHVTAGFGDVGFCGFWTLEIFCVHPIRVYPGVEICQIFYHTIEGKYENYKSGKYQHNKGIQPSLLYKDFEK
What is the function of this protein?
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
What are the official names of this protein?
dCTP deaminase, dUMP-forming, Bifunctional dCTP deaminase:dUTPase, DCD-DUT.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: TRMD_MESHJ
Sequence: MKINILTLFPRYFEVFCRESIIGKAIKQKKITINVVNFRDFSKNKHKKVDDYVYGGGPGLLLQIQPVVDALEKVGGLKIALSPQGQKFDQSVARKLAKEDEITILCGHYEGFDQRIIDNFIDFELSLGDFILTGGEIAAMAIIDAIIRLKPDIINPESLKNETFNDFLLDFPQYSRPANFRGLEVPKVLISGNHREIGEWRQEQRELITKKKRPDLWEKFLKIKNKK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POTA_STRA1
Sequence: MTNPIIAFKNVSKVFEDSNTVVLKDINFELEEGKFYTLLGASGSGKSTILNIIAGLLEASTGDIYLDGKRINDVPTNKRDVHTVFQNYALFPHMTVFENVAFPLKLKKMDKKEIQKRVQETLKMVRLEGFEKRAIQKLSGGQRQRVAIARAIINQPKVVLLDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNEGEIVQSGTPVDIYDEPINHFVATFIGESNILSGKMIEDYLVEFNGKRFEAVDGGMRPNESVQVVIRPEDLQITLPDEGKLQVKVDTQLFRGVHYEIIAYDDLGNEWMIHSTRKAIEGEVIGLDFTPEDIHIMRLNETEEEFDARIEEYVDTDDHEDGLINAIEEERNEENL
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HSSS_STAAC
Sequence: MFKTLYARIAIYSITVILFSALISFVLTNVYYHYNLKASNDAKIMKTLKEARQYEQSAKPTHIQQYFKHLGQMNYQIMTIDQKGHKTFYGEPFREDTLSQNAINNVLNNQDYHGIKDKPFALFVTGFFDNVTDNTVGINFKTKDGSIAVFMRPDIGETFSEFRTFLAVLLMLLLFISISLVIASTYSIIRPVKKLKLATERLIDGDFETPIKQTRKDEIGTLQYHFNKMRESLGQVDQMRQHFVQNVSHEIKTPLTHIHHLLSELQQTSDKTLRQQYINDIYTITTQLSGLTTELLLLSELDNHQHLLFDDKIQVNQLIKDIIRHEQFAADEKSLIILADLESINFLGNQRLLHQALSNLLINAIKYTDVGGAIDIALQHSHNNIIFTISNDGSPISPQAEARLFERFYKVSKHDNSNGLGLAITKSIIELHHGTIQFTQSNEYVTTFTITLPNNSL
What is the function of this protein?
Member of the two-component regulatory system HssS/HssR involved in intracellular heme homeostasis and tempering of staphylococcal virulence.  HssS functions as a heme sensor histidine kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to an aspartate residue of HssR.  HssR/HssS activates the expression of hrtAB, an efflux pump, in response to extracellular heme, hemin, hemoglobin or blood (By similarity).
What are the official names of this protein?
Heme sensor protein HssS.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AMP3_HETSP
Sequence: MSRRLILTLVLVTMLVKTMAGMESKWVETTDEIKKRSGTPEKERESGRLLGVVKRYIVCVRNPCPGRRAISEQT
What is the function of this protein?
Possesses antimicrobial activity against both Gram-negative and Gram-positive bacteria, as well as against the fungus C. tropicalis.  Also possesses a relatively high hemolytic activity.
What are the official names of this protein?
Antimicrobial peptide HsAp3.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Medium-length antimicrobial peptide (group 3) family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a helical membrane channel in the prey.
Protein: VPC47_MYCTO
Sequence: MIYMDTSALTKLLISEPETTELRTWLTAQSGQGEDAATSTLGRVELMRVVARYGQPGQTERARYLLDGLDILPLTEPVIGLAETIGPATLRSLDAIHLAAAAQIKRELTAFVTYDHRLLSGCREVGFVTASPGAVR
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.  Its toxic effect on colony formation is neutralized by coexpression with cognate antitoxin VapB47 (By similarity).
What are the official names of this protein?
Ribonuclease VapC47, RNase VapC47, Toxin VapC47.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: HEMH_WOLPM
Sequence: MKKAVILFNLGGPDSLNAVRPFLFNLFYDRRIINLPNPFRFLLAKFISAKRENTARKIYEEIGGKSPILENTKMQANASELKLNENRNHVHKVFICMRYWRPFADEVIESVKQFDPDEVILLPLYPQYSTTTTLSSIENWQKNAKRYGLKCNTKMIHRYYDNQDFIEAHTNLIAKYYKLARKIGKPRVLFSAHSLPLSIIKKGDPYASQVERSVELIVEKLAINNLDWSICYQSKIGPVKWLEPSTESELLRAKADGVPVVLSPISFVSEHSETLVELDIEYKAIIKDGYYFRVPTLSTDPLFIKCLADLCINLP
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_CHLTE
Sequence: MKRDYYEILGVARSADKDEIKKAYRKLALKYHPDKNPDNKEAEEKFKEVNEAYEVLSNDDKRRRYDQFGHAGVGSSAASGSGPGGAGYGDINDIFSAFNDMFSGGGGRARTGGSPFSGFEDVFSGGFSGSGSGRRRSAGIQGTDLKIRLKLTLEEIAKGVEKTIKIKKLVTCRECNGTGSKSGKTEICPTCHGSGEVRQATKTMFGQFMNISVCPTCGGEGRVVKDRCPSCYGEGIKQGEATVKITVPAGVQDGNYLTLQGQGNAGPRGGAPGDLIVVIEEKPHELFKRNGDDIIYDLSVGFPDLVMGTKIEVPTLDGHVKLTIPAGTQPNTMLRIGGKGIGHLRGGGSGDLYVRVNVFVPKEVSGKDRDLLKELKKSTVICPNHGDENHEKSIFEKAKDIFS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_SHEON
Sequence: MPIIKVRENEPFDVALRRFKRSCEKAGILADVRAREFYEKPTTARKRAKAAAVKRLAKKLSRENARRVRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: NOMO1_HUMAN
Sequence: MLVGQGAGPLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYTKHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGGDINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGDYEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSSLVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERITFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTKADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIIATGFSVCGQISIIRFPDTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPEAETRAGLTLKPQTFPLTVTNRPMMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKVNAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDMSAVEFRQTGYMLRCSLSHAITLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILTLTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQEREKNGNEEGEERMTKPPVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSMEAVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVISEKGASSPLITVFTDDKGAYSVGPLHSDLEYTVTSQKEGYVLTAVEGTIGDFKAYALAGVSFEIKAEDDQPLPGVLLSLSGGLFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFRFEPSSQMIEVQEGQNLKITITGYRTAYSCYGTVSSLNGEPEQGVAMEAVGQNDCSIYGEDTVTDEEGKFRLRGLLPGCVYHVQLKAEGNDHIERALPHHRVIEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWVKLYKSENLDNPIQTVSLGQSLFFHFPPLLRDGENYVVLLDSTLPRSQYDYILPQVSFTAVGYHKHITLIFNPTRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKLIPLLLQLTSRLQGVRALGQAASDNSGPEDAKRQAKKQKTRRT
What is the function of this protein?
Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes (PubMed:36261522, PubMed:32820719).  The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions (PubMed:36261522).
What are the official names of this protein?
BOS complex subunit NOMO1, Nodal modulator 1, pM5 protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: Y5435_MYCS2
Sequence: MSRFTEKMYRNARTVTTGMVTGEPHEPVRHTWGEVHERARRIAGGLAAAGIGHGDAVGVLAGFPVEIAPTAQGVWMRGASLTMLHQPTPRTDLAVWAEDTMNVIGMIELKAVIISEPFLVATPVLEEKGILVLKVADLLAADPIDPVETGEDDLALMQLTSGSTGSPKAVQITHRNIHSNAEAMFVGAKYDVEKDVMVSWLPCFHDMGMVGFLTIPMYFGAELVKVTPMDFLRDTLLWAKLIDKYKGTMTAAPNFAYALLAKRLRRQAKPGDFDLSTLRFALSGAEPVEPADVEDFLDAGKPFGLRPEAILPAYGMAETTLAVSFSPCGEGLVVDEVDADLLAALRRAVPATKGNTKRLASLGPLLNDLEARVVDENGEVMPARGVGVIELRGEPVTPGYITMGGFVPAQDEYGWYDTGDLGYITEEGNIVVCGRVKDVIIMAGRNIYPTDIERAAGRVEGVRPGCAVAVRLDAGHSRETFAVAVESNAWQDPAEVRRIEHQVAHEVVSEVDVRPRNVVVLGPGSIPKTPSGKLRRANSVSLVTQ
What are the official names of this protein?
Putative ligase MSMEG_5435/MSMEI_5285.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: CARB_LEPIC
Sequence: MPRREDIRSVLILGSGPIVIGQACEFDYSGTQAAKALKEKGIRVILLNSNPATIMTDPDLADATYVEPMTVPVVQKILEKEKPDAILPTVGGQTALNLALACNSAGILEKYNVELIGAKVDAIKKAEDRELFKKAMEKIGVRVPASGLANNLKDAVEIKNKLGLPLIVRPAFTLGGTGGGIAYTEETFEEVVSKGLKASPISQVLLEESVLGWKEFELEVMRDLADNVVIICSIENIDPMGVHTGDSITVAPQQTLSDKEYQNLRDMSIAIIREIGVETGGSNIQFAVNPTNGDVIVIEMNPRVSRSSALASKATGFPIAKIAALLSIGYTLDEIKNDITRVTPASFEPSIDYVVTKVPRFAFEKFPGTDDTLGVQMKAVGEAMAIGRTFKESFQKALRSLEIDRYGFGSDGYFQELLYSRSLNNDQRKEWIDSHLKRPNDKRIFYVKLAFDEGYTVDQIHDLCKIDRWFLWQMEGLLKLEKEYSEKGNSILYKMKQVGFSNRQLSFLKNKKQILDLLDGNLRVDLKKTEIQNLLKLSEEEIEVELGSKKILPVYKRIDTCAGEFEAYTPYFYSSYDEEDESDVTNAKSVMILGGGPNRIGQGIEFDYCCCQASYALQDLGIESIMINSNPETVSTDYDTSDRLYFEPLTLEDVYRIYQNEKPEGVIIQFGGQTPLKLAKDLEKKGVKILGTSPDSIDRAEDRKRFVEVLEKLKLNSPESGIATSMEEAREIAHKIGYPVLVRPSYVLGGRAMLIINEEKELDRYMEKAEEISKDRPLLIDSFLEDAIEVDVDALCDGKEVFVTGIMEHIEEAGIHSGDSACVLPPQTLSKNMMDEIRKATVNLALELQVKGLINIQYAVKNEILYIIEVNPRASRTVPFVSKALGHPIVKYATRIMMGESLKSLPLPKEMEFSQVSVKEVVLPFNKFPGVDTILGPEMRSTGEVMGIASTAGEAFLKSQYMAGDELPSQGTVFVSINDKTKAELLSYIKDLSELGFNLIATSGTHKFLSDNGILSSKINKVYDGIFPTALDYIRENKIHLIINTPLSRVTRDDSFTIRQAAIRFKVPCLTTSNAAKALIKGMVEMKNKGFTIHSLQEIHAMPKIL
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: RECR_DEIGD
Sequence: MKYPPSLVGLIRELSRLPGIGPKSAQRLAFYLFEQPREDIERLAGAILEAKRDLHTCPVCFNITDAERCDVCSDPTRDQSVICVVEEPGDVIAIERSGEYRGLYHVLHGALSPMNGVGPDRLQIRPLLPRVQDGMEVILATGTTVEGDATALYLQRLLEPLGAVVSRIAYGLPVGGALEYADEVTLGRALSGRRRVSEPASPPPPRRNDEEQDGAPARPPSH
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: TTCA_ECO24
Sequence: MSQNQEISKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMVCLSGGKDSYTMLEILRNLQQSAPINFSLVAVNLDQKQPGFPEHVLPEYLEKLGVEYKIVEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFLNMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIQRFADAKAFPIIPCNLCGSQPNLQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLCDTNLFDFKGITHGSEVVNGGDLAFDREEIPLQPAGWQPEEDENQLDELRLNVVEVK
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_ENT38
Sequence: MAVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLVEKNSKSGGRNNNGRITTRHIGGGHKQAYRIVDFKRNKDGIPATVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGDQIQSGVDAAIKAGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGIRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: LECB1_ARTIN
Sequence: NEQSGKSQTVIVGSWGAKVS
What is the function of this protein?
D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc (Thomsen-Friedenreich-antigen-specific lectin).  Potent and selective stimulant of distinct T- and B-cell functions.  Shows a unique ability to specifically recognize IgA-1 from human serum.
What are the official names of this protein?
Agglutinin beta-1 chain, Jacalin beta-1 chain.
What is the protein family that this protein belongs to?
Belongs to the jacalin lectin family.
Protein: COX1_LOXAF
Sequence: MFANRWLYSTNHKDIGTLYLLFGAWAGMVGTAFSILIRAELGQPGSLLGDDQIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLIPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILSAINFITTIINMKPPAMSQYHMPLFVWSILITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMVSHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTIGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFIHWFPLFSGYTLNYTWAKIQFLVMFIGVNLTFFPQHFLGLSGMPRRYSDYPDAYTAWNTASSMGSFISLVAVILMVFMIWEAFASKREVSVMELTTTNVEWLNGCPPPHHTFEEPAYVKSNS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TI214_DIOEL
Sequence: MIFKSFLLGNLLSLCIKIINSVVVVGLYYGFLTTFSIGPSYLFLLRARVMEEGTEKEVSATTGFITGQLMMFISIYYAPLHLALGRPHTMTVLVLPYLLFHFFWKNQKNFTSIRNASTRDSMCNLRNLNIQCVFLNNLIFQLLNHFILPSSTLARLVNIYMFRCNNKMLFVTSSFVGWLIGHFLFMKWLGLVLFWIPQNYSIRSNKYLVSELRNSMGRIFSILLFITCVYYLGRMPSPIVTKKLKEISETEEGGESEEESNVETTFETRDPKQEQEESTEEDPYLCWEEKEDPEKIDERKEIQVNEKEKTKNEFDFHFKETYYKDNPVHEDSYLDTYQDNWQLGRLKEDKKQKTYLIYKKPLVNFLFDYKRWNRPLRYIKNDRFENVVRNEISQYFFYTCPSDGKKRISFTYPLSLSTLSEMIERKIFLYTTEKLSHEGLYNYWVYTNEQKKYNMSNELLSRIKVLEKEKKSLVIDMLEKRTRLYNDENEQKCLHKTYDPLLNGPYRGTIKKLYSKNDLISNRNRTTEDAIETFWINKIHDILYIYNDSRKFEHQKNLLDGESVLNFIGNSLSSISIGKFYLESTHSFNLKKFSLLSLLAEQKTIDLESQAKSLKFRIDGITTDLNDETTIRNKSIGIEEILKKVPRWSYKLTNGLEEEDENEEESTEDPGLRSRKAKRVVIYTDNDQNTNSITTNNSISNNDEVEEVALIRYSQQSDFRRDIIKGSMRAQRRKTVTWEMFQANMHSALFLDRIDKTFFFSSFDISEMRNIIFRNWLRREPELRISECEEETKEKGKKYKEKKEENKRIRIAISETWDTIIFAQAIRGSMLITQSFLRKYIILPSLIIAKNIGRILLFQFPEWDEDLKEWNREMHVKCTYNGVQLSETEFPKDWLTDGIQIKILFPFCLKPWRKPKVRSNLTKKKRKKENFCFLTIWGMEAELPFGSPRKQSSFFEPIYKELEKKMRKVKKKFFRVLRVFKERKKGFLKVRKEKTGWILPIVLIRKQIMKEFEKINPIFLFKLSKVKVYEPHEKKKNDKTPNKITRESSIQIRSMNWTNYSLIEKKMKDLADRTLTTRNQIEQITKDNKKIAIICDGKRLESRKKIFQILKRQYIRLLRKSDSFMKSFIEKIYINIFLCTINIFSINIQLFFESKKKNLNKSTIYNDETNQNTMNFISTLKKSFSNTINSTTLITNISNNSNIYYNLSSLSQAYVFYILSQTQLFNKYHLRSVLHYDRTYPFLRDTIKNYCMTQGIFDTKSRYKKIHKSEINEWKNWLRDHYQYKLSQTKWFRLVPQKWGNKVNKHYIIQNKDKDSIKLDSYKKEKDQLIHYMKQNHNYDAVDSLTSQKEKLKKHYRYDLLSHEYMNYGNREDSYIYESTLQVNGNQEISYNLYTMKAESYYILITIVINDYLEEGYIVDMDQNMNRKYFDSRILCFPIRKNIDIEAWINAHIDTKINKNLKTETNNYQKLAKKKLFVFDWIGMNEERLYHKISNPEPWFFPEFWLLFNAYKIKPQIIPIQLLFLNFYFYENISQSNNINLDQKKNPHISSNQKEYLEFENSNQEKNEQQGQGDLRSDLRKQKKKDVEENHTKSEIKKHKKKKQSKSNKEAELYFFLKKYLLFQLRWDDSLNQRMIDNIKVYCLLLRLINTKEIVISSIQRGEMCLDVMLIQKDLALTELIKKGILIIEPIRLFLERGVKLIIYQTIGISLINKNQTNGKYLKKRYVDKKSFDRYIGRYNNMLANGDKNHYDFFVPENILSPRRRRELRILICFNSCNWNVVDRNPAFCNENKIKNYRQFLNKHLNTDTNKFTKFKLFLWPNYRLEDLACMNRYWFDTNNGSRFSMSRIHMYPRFRII
What is the function of this protein?
Involved in protein precursor import into chloroplasts.  May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope.
What are the official names of this protein?
Protein TIC 214, Translocon at the inner envelope membrane of chloroplasts 214, AtTIC214.
What is the protein family that this protein belongs to?
Belongs to the TIC214 family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: DCD_BURVG
Sequence: MSIKSDKWIRRMAEEHKMIEPFVPDQVRASEDGRRIVSYGTSSYGYDIRCADEFKIFTNINSTIVDPKNFDEGSFVDFKGDVCIIPPNSFALARTVEYFRIPRTVLTVCLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFFESDEVCDVSYADRGGKYQGQRGVTLPKT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: APOC1_PLEMO
Sequence: MRLFLSLPVLVVALLTILEGPGPAQGAPEAVDTSTGLDKLKEFGNTLEDKVREFFNRVKESDIPAKTRNWFSETLQKVKEKLRIES
What is the function of this protein?
Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor.  Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL.  Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP).  Binds free fatty acids and reduces their intracellular esterification.  Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.
What are the official names of this protein?
Apolipoprotein C-I, Apo-CI, ApoC-I, Apolipoprotein C1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C1 family.
What are the subcellular locations of this protein?
Secreted.