PharMolix/UniProtQA huggingface dataset:
Protein: PEBP1_BOVIN
Sequence: MPVDLSKWSGPLSLQEVDERPQHPLQVKYGGAEVDELGKVLTPTQVKNRPTSITWDGLDPGKLYTLVLTDPDAPSRKDPKYREWHHFLVVNMKGNNISSGTVLSDYVGSGPPKGTGLHRYVWLVYEQEGPLKCDEPILSNRSGDHRGKFKVASFRKKYELGAPVAGTCYQAEWDDYVPKLYEQLSGK
What is the function of this protein?
HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system.  HCNP increases the production of choline acetyltransferase but not acetylcholinesterase.  Seems to be mediated by a specific receptor (By similarity).
What are the official names of this protein?
Phosphatidylethanolamine-binding protein 1, PEBP-1, Basic cytosolic 21 kDa protein, HCNPpp.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylethanolamine-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: E4PD_PSYIN
Sequence: MSIRIAINGYGRIGRSVVRALYENNRQDEMKVVVINELAEPSAIAHLTQYDSTHGRFPFPVNLQNNLLKIKNDDIHLVRFSELADLPWHEHDIDIVLDCTGIYGSRADADAHIAAGAKKVIFSHPADPDVDATVVYGINHQQLTGDETFISGASCTTNCMVPVIDTLDKHFAIKCGTITTIHSAMNDQPVIDAYHSDLRRTRAASQSIIPVDTKLAAGIERILPKFANKFEAIAVRVPTINVTAMDLSITVSKDVTIQEINDCLLKASETNLKDILGYTEAPLVSIDFNHDPRSCIIDGTQTRVSDGNLVKLLVWCDNEWGFANRLLDTSFYLANLAEQKRLQSTETVKSLEDTGISNEIKDELQDRRKII
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MI40A_XENLA
Sequence: MSYCRQEGKDKIIFVTKEDHETPSSAELIADDPNDPYEDQGLILPNGDINWNCPCLGGMASGPCGEQFKSAFSCFHYSQEEIKGSDCLDQFRGMQECMQKYPDLYPQEDDEEEAEKEKQNKEAEPSVTQSSDTKEESSS
What is the function of this protein?
Central component of a redox-sensitive mitochondrial intermembrane space import machinery which is required for the biogenesis of respiratory chain complexes (By similarity).  Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17 or MICU1.  Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS).  Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria.
What are the official names of this protein?
Mitochondrial intermembrane space import and assembly protein 40-A, Coiled-coil-helix-coiled-coil-helix domain-containing protein 4-A.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space.
Protein: FBW4_ARATH
Sequence: MGRTETGDESSARKMRRKVPTSIESLDADILCIIFSFLDLFDLVHCTVVCNSWNAVIKRLKLLQASCRKMHHLGSDSPSSSTSLDRPAEIDVEDFAMKHHKMALLRGRIEIERWEAHSHRVSQCRMKKGLLLTGVGDKVMRLWSLKSYKCMEEYSLPDASSLIDFDFDESKKLEVVSLAWEYFDSVVVVVVEIVGLVGTRISIWRRNGQRSIFPSRAGTFPKGLCMRYIDPEAVVGCEDGTARVFDMYSKTCSQIIRTQGGPITCLSLSDNQLFLSGSSLGRVTVSDPLMDQPVATLKSTITAGGIQTICFNQGTNLAFIGTTGGYVSCWDLRKMDRLWEKRVSPNVVYSIQQLRNDTSVMVAGGIDGVLRMIDQKSGRVLSRVIMDDKFSTTSTRNNQVVIEKRRGKRVSQDMEIDKIERKVRPQISCIAMGMKKMVTAHNGKCISVWKFNLS
What are the official names of this protein?
F-box/WD-40 repeat-containing protein At3g52030.
Protein: RENI_RAT
Sequence: MGGRRMPLWALLLLWTSCSFSLPTDTASFGRILLKKMPSVREILEERGVDMTRISAEWGEFIKKSSFTNVTSPVVLTNYLDTQYYGEIGIGTPSQTFKVIFDTGSANLWVPSTKCGPLYTACEIHNLYDSSESSSYMENGTEFTIHYGSGKVKGFLSQDVVTVGGIIVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAVDGVIPVFDHILSQRVLKEEVFSVYYSRESHLLGGEVVLGGSDPQHYQGNFHYVSISKAGSWQITMKGVSVGPATLLCEEGCMAVVDTGTSYISGPTSSLQLIMQALGVKEKRANNYVVNCSQVPTLPDISFYLGGRTYTLSNMDYVQKNPFRNDDLCILALQGLDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR
What is the function of this protein?
Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
What are the official names of this protein?
Renin, Angiotensinogenase.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted. Membrane. Note=Associated to membranes via binding to ATP6AP2.
Protein: YTTP_BACSU
Sequence: MKVSTKDKIIESAVMLFNQKGFSGTSVREIAKSADVNVAHISYYFKGKGGLMEHLVSEFYEGYSKTLETAASNISTQSTQEQLLQLVFDILSYQHNHRQLTRFVYREVTIDSTLIREIMSTYLMKEKYIFQLIIEEGEKQREYLTLPLPHFILQLKSLLMMPYLQPQYISEVLYMQPHEPYFYKMYFEEIKIWIRSVFRTGDVALTN
What are the official names of this protein?
Probable HTH-type transcriptional regulator YttP, Stress response protein YttP.
Protein: RS9_BACC2
Sequence: MAQVQYYGTGRRKSSVARVRLVPGEGRVIINGRDFENYIPFAALREVVKQPLVATETLGNYDVLVNVNGGGYTGQAGAIRHGISRALLKADPEYRLTLKRAGLLTRDARMKERKKYGLKGARRAPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: CLZ9_COCLU
Sequence: MAASTKPTTKLSTEEDDVSRRDSESSADFMKSNEELQATMIPEDDGANPATGQPTWTILSDTEIKSVLVVASFAAAISPFSTSTYYPVVTAIARDLGVSVSKINLTMSSYQIFQGVAPTITAAFADTYGRRPMFLVCFVTYFVANVGLALQNDFTTLLVLRCLQSTGSSGTFALAQAVTADITTRAERGRYLIYATLGSTLGPFIGPVIGGLLVKFLGWRSVFWFLLCMGTVFALLIFIFFGETARPIVGDGSIPPQSWNRSYLQMRSKGVSNLKPNLASLERRKSRPNPLTSLALLWDRENFILSVSGGLLYAGYSSVTSVLASQLQQRYKYDAVQVGLCYLPVGFGSLLAYRTTVRLMDWNFEREAKKQGLVIVKNRQTDISRFDLEKARLGFVFPMILVCSGLLVAYGWQMHYHAPLAPILVTMFLIAIILTGVMNAIAALLTDVNRENAAAVGAAMNLTRLLLGAGAVAVVGPLNKSAGIGWTATVTAGFSYNVNTKGIQTKRRAAAIFEVSRATLHRRCDGKRARRDCQPNSKKLIQQEEEVILKYILDLDTRGFLPTYAAERGMADKLLSTRGGSPVGRDWPRNFVKHKAKYSILDEDVYSFDEAGFMMGKITTQLAVTGSERRGRPKAIQPENREWVTLIQGINAAGWAISPFVVFAGQHHLSAWYEEDIPRDWAIAVSDNGWTTNEIGVEWLEHFIKYTDGKAVGVRRLLIFDGHESHHSLKSRELCKENNIYTLYMPPHSSHLLQPLDIGCFSPLKRAYSREIEALICHHINHITKLEFLPAFKAAFQRSFTSANICSSFRGAGLVPLQPDIVLSKLDVRLLTHIPAASPEAPWEAKTPSNRKKKQIQKRGTLTKGEGEDTLAQKEADQQIEREQRQGGEQSGRSRQALARSLEALEVGGVAHSLNGSFV
What is the function of this protein?
MFS-type transporter; part of the gene cluster that mediates the biosynthesis of squalestatin S1 (SQS1, also known as zaragozic acid A), a heavily oxidized fungal polyketide that offers potent cholesterol lowering activity by targeting squalene synthase (SS).
What are the official names of this protein?
MFS-type transporter clz9, Squalestatin S1 biosynthesis cluster protein clz9, Zaragozic acid A biosynthesis cluster protein 9.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. CAR1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PUR5_STRA1
Sequence: MSEKNAYAKSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFGGMFDLSKTGVREPVLVSGTDGVGTKLMLAIKYQQHDTIGQDCVAMCVNDIIAAGAEPLYFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAVGVAEKSQIIDGSKVKEGDILLGLASSGIHSNGYSLVRRVFADYTGNEVLPELEGKQLKDVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDEDKVPVLPIFNAIEKYGDIKHEEMFEIFNMGVGLMLAVSPENVNRVKELLDEPVYEIGRIIKKADDSVVIK
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_PROST
Sequence: MHNESPIKRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEATVRQIQSLERVGVDIVRVSVPTMDAAEAFKLIKQRVNVPLVADIHFDYRIAMKVAEYGVDCLRINPGNIGSEERIRQVVDSARHHNIPIRIGVNGGSLEKDIQEKYGEPTPEALVESAMRHVDILDRLNFDQFKVSVKASDVFLAVGSYRLLAQKIDQPLHLGITEAGGARSGSVKSAIGLGMLLAEGIGDTLRISLAADPVEEVKVGFDILKSLRIRSRGINFIACPTCSRQEFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEAEVSTLGVAGAKTKSGFYEDGVRKKERFDNDNIIDQLEAKIRAKAAMLDEITV
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity).  Involved in density-dependent regulation of 2'-N-acetyltransferase (PubMed:9079912).
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: ARGB_ROSDO
Sequence: MKTQDMNRDWISTASTLNKALPYLQRYAGATVVIKLGGHSMGSDEAMDEFARDVVLMRQVGVNPVIVHGGGPMINAMLDKLDIKSEFVNGKRVTDRATMDVVEMVLSGLVNKRIVQAINGQGGCAVGISGKDARLITCCQTDPDLGFVGTPQDVDPRLLRDLTEKEYIPVIAPLGADQTGQTYNINGDTAAGAVAAALKADRLLLLTDVAGVKNDAGDVLTELSAKQIEDMTRDGTIAGGMIPKTETALAALRGGVRAAVILDGRAPNACLLELFTEHGAGSIIRAD
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_PROMH
Sequence: MNDAKYGVLLVNLGTPDAPQPDAVKRYLAQFLSDPRVVDVSPWIWKPILHGVILPFRSPKVAKLYQQIWLPDGSPLLVYSRAQQKALAQRFAHIPVELGMCYGNPSLNEGLTRLLAQGVEKLIVLPLYPQYSCSTSGAVFDGISQLFKTMRTIPSLHFVRSYAQHPLYIKALVNSIDESFKQHGKPDRLVLSFHGIPERFIKTGDIYFDECCLTVEKLKQQLDYPAEKVMMTFQSRFGREPWLSPYTDKTMEKLGSEGVEHVQVICPGFSSDCLETLEEINEQNREFFIHGGGKQYEYIPALNDKVEHIDLLEAIIRDICEK
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAHO_STRCA
Sequence: GPAQPTYPGDDAPVEDLVRFYDNLQQYLNVVTRHRY
What is the function of this protein?
Hormone secreted by pancreatic cells that acts as a regulator of pancreatic and gastrointestinal functions.
What are the official names of this protein?
Pancreatic polypeptide, PP.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: IF3_STRP4
Sequence: MFFSNKTKEVKTIAKQDLFIXDEIRVREVRLIGLEGEQLGIKPLSEAQALADNANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGDFDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKMDGRQMFMQLAPATDKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAMA_BACHK
Sequence: MNSELFSPYTIKDVTLKNRIVMSPMCMYSSENEDGQVTNFHLIHYGTRAAGQVGLVMIEATAVLPEGRISNKDLGIWDDSLIEGLHKTTTFIHDNGAKAAIQLAHAGRKAELETDALAPSAIPFNETMKIPVEMSIQQIKNTILAFQQAAVRSKQAGFDVIEIHGAHGYLINEFLSPLSNKRTDEYGGSPEKRYRFLREIIDSINEVWNGPLFVRISANDYHPDGLTVQDYIQYTKWMKEQGVDLIDCSSGAVVPARIDVYPGYQVQYAKHIKEHANIATGAVGLITTGAQAEQILTNNEADLIFIGRELLRNPYFPRIAANELGFELEEPYQYERAPGKISTNK
What is the function of this protein?
Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones.  It also reduces the nitro group of nitroester and nitroaromatic compounds.  It could have a role in detoxification processes.
What are the official names of this protein?
NADPH dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily.
Protein: RL34_MYCSS
Sequence: MAKGKRTFQPNNRRRARVHGFRLRMRTRAGRAIVTGRRRKGRRSLTA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: ITR2_OPUST
Sequence: QQCAERGQSCNPYEGIECCGDILCIQPRIWPPVPGRCA
What is the function of this protein?
Inhibits trypsin-like proteases from the guts of the insect pests P. truncatus, P. americana, Acheta sp and Gryllus sp.
What are the official names of this protein?
Trypsin inhibitor 2, OsTI 2.
Protein: MURD_YERPN
Sequence: MVDYQGKKVVIIGLGLTGLSCVDFFIARGVTPRVMDTRINPPGLDQLPESVEQHVGDLNQEWLLDADLIVVSPGMALAHPALSEAAEAGVEIIGDIELFCRENQAPVVAITGSNGKSTVTTLVGEMAKAAGWSVGGGGNIGVPALTLLKQDNQLTVLELSSFQLETTHSLRASAATILNVTEDHTDRYPLGLQQYRAAKLRVYENAKVCVVNADDALTMPVRGADSRCISFGVDVGDYHLNKQQGEIWLRVRGEKVLNTREMKLSGRHNYTNALAALALADAVGIPRASSLKALTTFSGLPHRFQLVLERHGVRWINDSKATNVGSTEAALDGLQVDGTLHLLLGGDGKSADFSGLTHFLQGDRIKVYCFGRDGGQLAALRPDVSQLTETMAQAMALVAKVVLPGDRVLLSPACASLDQFRSFEHRGNEFARLAEELG
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_SALAI
Sequence: MSAKSTARFTPAGQLTAEDLGAIHLIGVGGVGMSGLARLFLTRGISVSGSELREWPSLAGLRALGGTIYMSHEVANLDGVDTVVYSSAIPQDHLELVEARRRGLRVLHRSEALAAAMTGRRTVAVAGTHGKTTTTSMVTMVLQQAGVDPSFVIGGEISEVGSGAHHGTGEYFVVEADESDRSFLIYRPFVSIITNIEADHLNTYGDLANLEAAFADFARLTDPDGFVVTCADDAGSRRLAETLRAEGRRVYTYGTSTDADLRLTEMASSTRGIRYLAEVDGRSLGEFRLPVPGRHMGLNSASAVLAAYLLGLPLDAAEAALAAFPGVRRRFERKGVADNVLVYDEYAYHPTPIALALRTLREVAGDGRLIVVFQPYRLYRTRDLQTEIAEALAIADELVLLEVFGPGELREPGEGSAALIEAVPLPADRKVFVDSWEAAPVEVARRARPGDVVVTMGAPPSSLMGEQLLDALSARRAGSPVGTVPGGEVGGATTIGGTVPGGSAPGASAAG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_SHIBS
Sequence: MSLTRLLIRDFRNIETADLALSPGFNFLVGANGSGKTSVLEAIYTLGHGRAFRSLQIGRVIRHEQEAFVLHGRLQGEERETAIGLTKDKQGDSKVRIDGTDGHKVAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWACFHNEPGFFTAWSNLKRLLKQRNAALRQVTRYEQLRPWDKELIPLVEQISTWRAEYSAGIAADMADTCKQFLPEFSLTFSFQRGWEKETEYAEVLERNFERDRQLTYTAHGPHKADLRIRADGAPVEDTLSRGQLKLLMCALRLAQGEFLTRESGRRCLYLIDDFASELDDERRGLLASRLKATQSQVFVSAISAEHVIDMSDENSKMFTVEKGKITD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_CHLPM
Sequence: MLIIDGKKVSLELKDELKASVDRYRETTGKVPGLTVIIVGEDPASQVYVRNKAKTCKEIGMNSSVITMPADTPEEHLLDTIASLNLDPAVHGILVQQPLPEQIDEFAVTLAIDPQKDVDGFHPENLGRLVMGHLDKCFVSCTPYGILELLGRYGIETSGKHCVVVGRSNIVGKPMANLMLQKLKRSNCTVTICHSATQDIASYTRQADILIAAIGRAKFITPDMVKEGAVVIDVGINRIDDPTTKSGTRLVGDVDYEGVSALASAMTPVPGGVGPMTIAMLLKNTLHSFERTHNL
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: A1HB2_LOXIN
Sequence: ARVVLGCWSVLSQAAQTDDEERAGNRRPIWIMGHMVNAIGQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRNCKKYENFNDFLKGLRSATTPGNSKYQEKLVLVVFDLKTGSLYDNQANDAGKKLAKNLLQHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFKDQLTKDGHPELMDKVGHDFSGNDDIGDVGKAYKKAGITGHIWQSDGITNCLPRGLSRVNAAVANRDSANGFINKVYYWTVDKRSTTRDALDAGVDGIMTNYPDVITDVLNEAAYKKKFRVATYDDNPWVTFKK
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (PubMed:9790962).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces hemolysis, dermonecrosis, vascular permeability and platelet aggregation (PubMed:9790962).
What are the official names of this protein?
Dermonecrotic toxin LiSicTox-alphaIA1bii, LiRecDT1, Loxtox i4, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D 1, SMD 1, SMase D 1, Sphingomyelinase D 1.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily. Class IIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS3_PARP8
Sequence: MGQKIHPTGFRLAVSRNWASRWYANNNNFAAMLQEDIGVREYLKKKLKNASVGRVVIERPAKNARITIFSSRPGVVIGKKGEDIELLKSELQKRMGVPVHVNIEEIRKPETDAQLIADSITQQLERRIMFRRAMKRAMQNAMRLGAQGIKIMSAGRLNGIEIARTEWYREGRVPLHTLRADIDYATSEAKTTYGIIGVKVWVYKGDTLGRNDAPVVEEVAEEKRPRRNARPGDRRPRRDGEGAPAGARRGAPRRGGAGDGKTGE
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: TDH_SALA4
Sequence: MKALSKLKAEEGIWMTDVPEPEVGHNDLLIKIRKTAICGTDVHIYNWDDWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGGRTHLCRNTTGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLASIFDPFGNAVHTALSFDLVGEDVLVSGAGPIGVMAAAVAKHVGARHVVITDVNEYRLELARKMGVTRAVNVAKESLNDVMAELGMTEGFDVGLEMSGAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKVIFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSIDDFQKGFDAMRSGQSGKVILSWD
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QCR8_BOVIN
Sequence: MGRQFGHLTRVRHVITYSLSPFEQRAFPHYFSKGIPNVLRRTRACILRVAPPFVAFYLVYTWGTQEFEKSKRKNPAAYENDR
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
What are the official names of this protein?
Cytochrome b-c1 complex subunit 8, Complex III subunit 8, Complex III subunit VIII, Ubiquinol-cytochrome c reductase complex 9.5 kDa protein, Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C.
What is the protein family that this protein belongs to?
Belongs to the UQCRQ/QCR8 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RS11_UREP2
Sequence: MAKKKKLSFTNGIAYIHATKNNTIITLADEQGSVLSWASSGSIGYKGTKKKTPYSAGIAAEAAAKAVIDMGLKSVEVHVNGTGASRDTAIRSLQAAGLEVTKIKDVTPIPHNGCRPPKKPR
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RL25_ANOFW
Sequence: MISLLQLQLRTDHRRSYVKQMRKQGHIPAVLYGKTTNSQPVFVDAAEFLKQLRATGGTGLLDAKMNDNHIRIIVRDMQKHPIRHDIIHIDFLAVDAKTEIDVHVPIHLVGEAAGVKDGGVLQQAMHQLSIRVLPSNIPPSIDVDITNLQVGDVITVSHIQTNGAYEINHDPTEVIASILPPKQEEEIHSGEEQEPGRPESEEGRETTP
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: ILVD_DESAP
Sequence: MNSEVIKKGVERAPHRSLLRATGIIKDEADFQKPFVAIANSFAEIVPGHAHLNEFVKEIKEAVREAGGVPFEFNTLALCDGIAMNHPGMRYSLPSRELVADSVETMVQGHRFDGLICIPNCDKIVPGMLMAAVRLNIPTIFVSGGPMKAGRAKDGRPIDLISVFEGIGAFRAGKIDAGDLLELEQAACPGYGSCAGMFTANSMNCLCEALGLALPGNGTILAVDPRRSELKKWAGRQIVELIKRDLRPRDIVTPEAIDNAFALDVAMGGSTNTILHLLAVAQEAGINYPLKRVNLISARTPTLCKISPASSLHIEDVDRAGGVSAVLGELSRKPGLLNLDCLTVTGETLGETVGQVQSLDPRVIRGVEEPLSPVGGLKVLFGSLAPEGAVVKTAAVVPQMMRHQGPAVVFNSEAEASAAILGGRIKHGDVVVIRFEGPKGGPGFMEMLGPTAALVGMGLGESVALVTDGRFSGGTRGACIGHVCPEAASGGPIALIKDGDLISYDLEAGTLELLVPQEELAARKAAFTPPLRQGLTGWLARYVQMVAPASIGAVLRPACGRPPGEQDYE
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: Y1682_STAAW
Sequence: MDWILPIAGIIAAIAFLILCIGIVAVLNSVKKNLDYVAKTLDGVEGQVQGITRETTDLLHKVNRLTEDIQGKVDRLNSVVDAVKGIGDSVQTLNSSVDRVTNSITHNISQNEDKISQVVQWSNVAMEIADKWQNRHYRRGSANYKANNVATDANHSYTSRVDK
What are the official names of this protein?
UPF0478 protein MW1682.
What is the protein family that this protein belongs to?
Belongs to the UPF0478 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.