PharMolix/UniProtQA huggingface dataset:
Protein: HJC_SULTO
Sequence: MNSNKSRGSSVERYIVSRLRDKGFAVIRAPASGSKRKDHVPDIIALKSGVIILIEVKSRKNGQKIYIEKEQAEGIREFAKRSGGELFLGVKLPKMLRFIKFDMLRQTEGGNYAIDLETVEKGMELEDLVRYVESKISRTLDSFL
What is the function of this protein?
A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination.  Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.  Inhibits the helicase activity of Hel308 (Hjm).
What are the official names of this protein?
Holliday junction resolvase Hjc, Hjc.
What is the protein family that this protein belongs to?
Belongs to the Holliday junction resolvase Hjc family.
Protein: FLAW_ECOLI
Sequence: MNMGLFYGSSTCYTEMAAEKIRDIIGPELVTLHNLKDDSPKLMEQYDVLILGIPTWDFGEIQEDWEAVWDQLDDLNLEGKIVALYGLGDQLGYGEWFLDALGMLHDKLSTKGVKFVGYWPTEGYEFTSPKPVIADGQLFVGLALDETNQYDLSDERIQSWCEQILNEMAEHYA
What is the function of this protein?
Low-potential electron donor to a number of redox enzymes.
What are the official names of this protein?
Flavodoxin 2.
What is the protein family that this protein belongs to?
Belongs to the flavodoxin family.
Protein: PSBL_ARATH
Sequence: MTQSNPNEQSVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL35_DESHD
Sequence: MPKMKTHRGAAKRFKKTGTGKIVRHHAFTSHILEKKSPKRKRNLRKGTVMHKTDAKRIARLVAYL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: GATC_MYCTU
Sequence: MSQISRDEVAHLARLARLALTETELDSFAGQLDAILTHVSQIQAVDVTGVQATDNPLKDVNVTRPDETVPCLTQRQVLDQAPDAVDGRFAVPQILGDEQ
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C, Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: RPOB_SULNB
Sequence: MLNSLHSGNRLRVDFSKTPREIEIPNLLQLQQKSYENFLMLGERDRKHSTLERVFRSAFPIHDQQNRLTLTYKNSEIIKPKYTVRECMERGLTYSVSLKMNIALTIWNRDEKTGEKLDPKEIKEQAVFVRDIPLMTERTSFVVNGVERVIVNQLHRSPGVIFKEEESTTAGHKLLYSAQIIPDRGSWLYFEYDAKDILYARINKRRKIPVTILFRALDYTKEDIVKLFYPTKEISIKDNRFLVKFDPSDFSGRAEYDVKDMDGNVIVNAGKRLTKKKAQQLIENGLEWIEYPLEMLMERHLATAVIDQESGEVLYDVVAPLDETKLKKMIEQGIESIEIINDLAEGTDKSIINAFIADNESLRLLKQTEEIDDENVLSAIRIYKVMRPGEPVTPEAAKSFLRQLFFDPERYDLTEVGRMKMNHKLGLDIPQYATVLTAEDLINTVKYLIKVKNGHGHIDDRDHLGNRRIRAIGELLGNELHNGLVKMQKAIKDKMTTISGTLDELMPHDLVNSKMITNTILEFFSSGQLSQFMDQTNPLSEVTHKRRLSALGEGGLVKERAGFEVRDVHPTHYGRICPIETPEGQNIGLINTLATYSKVNEHGFIEAPYKVVKDAQVTDEIVYITATQEEDKCIAPASTKVDENGKIVEDLIETRLNGNIELNEAKRVDLIDISPLMISGSAAALIPFLEHDDANRALMGSNMQRQAVPLLKTDAPVVGTGMEAIVSRDAWEAVKAKRAGKVEKVDAKNIYIMGEDETGVFIDHYPLEKNMRTNQNTTFTQTPIVKLGDVIEVGQVIADGANMDQGELAIGKNIMVAFMPWYGYNYEDAIIVSEKIIREDTFTSVHTYEKEVEARELKHGTEEITRDIPNIREDELLHLDESGIVQLGTYVKPGMILVGKVSPKGEIKPTPEERLLRAIFGEKAGHVVNKSLYCPASMEGVVVDIKVFTKKGYEKDARAIQAYEEEKAILDSDHHDQLLMIDREEILRIAHYLSGQELAKDVTIGDKEYKAGSKIDEETIKGVNRFALRGVVQSYSDDVQNEYEALKNYFLKQKKRLKNEHEEKLSILEKDDILPSGVTKLVKIYIATKRKLKVGDKMAGRHGNKGIVSNIVPEIDMPYMEDGRPVEIILNPLGVPSRMNIGQILEVHLGLVGMRLGEQIQEMFDNKTADFIKELRAKMIEIADVAKLMNAKEVLSQMSDEELLAYGRDWSRGVKFAAPVFEGTNQTEFDKLFELAKIESDGKMTLYDGKTGEKMIERVNVGYMYMLKLHHLVDEKVHARSTGPYSLVTQQPVGGKALFGGQRFGEMEVWALEAYGASHILKEMLTIKSDDVEGRARAYRALTKGESVPASGVPETMFVLTKELQALGLDAELYESKKEVESEDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: TSAB_BUCAI
Sequence: MSNIILSIESSLDCCSVAIYKNEYIHSLSEKCKKKHTTHILPMIKEILSQTKTEFKELNYVSFSKGPGNFTSIRIAASIAQSLSISLKIPIISVSTLAIMAEKTFRKYKQKDVIVAIHAKKKQVYWAKYTRNKNSIWIGEYTESLLEKKIIQEKIENLKKRWTLVSDQSELIEFQNILNVKKNYVFLPNAKDIIPFVLLKIKNKNKSFSIENNINYLYNQF
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro.  TsaB seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity).
What are the official names of this protein?
tRNA threonylcarbamoyladenosine biosynthesis protein TsaB, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaB.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family. TsaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBM_SACHY
Sequence: MEVNILAFIATALFILVPTAFLLIIYVKTASQND
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL17_DEIRA
Sequence: MRHGKAGRKLNRNSSARVALARAQATALLREGRIQTTLTKAKELRPFVEQLITTAKGGDLHSRRLVAQDIHDKDVVRKVMDEVAPKYAERPGGYTRILRVGTRRGDGVTMALIELV
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: HST3_YEAST
Sequence: MTSVSPSPPASRSGSMCSDLPSSLQTEKLAHIIGLDADDEVLRRVTKQLSRSRRIACLTGAGISCNAGIPDFRSSDGLYDLVKKDCSQYWSIKSGREMFDISLFRDDFKISIFAKFMERLYSNVQLAKPTKTHKFIAHLKDRNKLLRCYTQNIDGLEESIGLTLSNRKLPLTSFSSHWKNLDVVQLHGDLKTLSCTKCFQTFPWSRYWSRCLRRGELPLCPDCEALINKRLNEGKRTLGSNVGILRPNIVLYGENHPSCEIITQGLNLDIIKGNPDFLIIMGTSLKVDGVKQLVKKLSKKIHDRGGLIILVNKTPIGESSWHGIIDYQIHSDCDNWVTFLESQIPDFFKTQDQIKKLRQLKREASDLRKQMKAQKDSIGTPPTTPLRTAQGIDIQGNNELNTKIKSLNTVKRKILSPENSSEEDEEENLDTRKRAKIRPTFGDNQAS
What is the function of this protein?
NAD-dependent histone deacetylase, which contributes together with HST4 to histone H3 'Lys-56' deacetylation, regulation of telomeric silencing, proper cell cycle progression, DNA damage control, DNA recombination, and genomic maintenance.
What are the official names of this protein?
NAD-dependent histone deacetylase HST3, Homologous to SIR2 protein 3, Regulatory protein SIR2 homolog 3.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MARH8_XENLA
Sequence: MHSCWNMKLQNEKTLGHSVSRSSNISKAGSPTSVSAPSRFPRTSVTPSSQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKFEFIMETKLKPLRKWEKLQMTASERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIRMGQNNGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETCKKKIFEKSVIIEPNLESKEALGIHHSDTNSSYYTEPEDCGAAILQV
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination of cd86 and MHC class II proteins, such as hla-dr alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies.
What are the official names of this protein?
E3 ubiquitin-protein ligase MARCHF8, Membrane-associated RING finger protein 8, Membrane-associated RING-CH protein VIII, MARCH-VIII, RING-type E3 ubiquitin transferase MARCHF8.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein. Lysosome membrane; Multi- pass membrane protein. Early endosome membrane; Multi-pass membrane protein.
Protein: FEH1_CAEEL
Sequence: MREGTPRVRIEVNKGSNRPSQFVSESEEQRLQRVQSRDSDTATMNFVTDDRMMEEHDEYSAFKEAYEEEESREYVIENGVKRLVNQHYDSRGYSSAGRGQKGRREEERRRNMAVDYSSQDFRQSLAAIDQASRDGAISRGEDGVRVRQIGDTTIMTEHRDPYSFYWQLDQARREAESPPRRPPPTDYVIDEEEEVLETVYSPEADDVMFENQYRRPVRHPLPPPPPIMEEEPKDLPPGWEKHEDPQGYSYYWHVDSGTIQRQPPPPVNRETQADAPPPQIIQLPPQQPVIEEHAFKQTTTKRRIEQDEMSEREIEDVAMIENGDTYHKPVRFAVRSLGWTDISEDELTAEKSSRAVNRAIVDLTTRSDIDSIPKWGDGRELIMELDDNELALLDPDSMNVIHSERIQAIRVWGVGRDNGRDFAYVSRDRGTRRFMCHVFRCDTSAKTIANTLRDICKRLMLHRRPSSLHAIESGEKRIVRSEGLTAPIDEPRKVIRCHFLGVTQVPKATGIEILNEAVDRLVSQVRSERWILADVSIAPSTIAIVEVNGQQIAECRVRYLSFLGIGRDVKHCAFIMQTSSESFMCYVFHVEPNAAAMAKMVEAACKLRYQKVLDAHSSSRHHSGMSIHGQHPPSTYHGKGWTETFRDAFGSVTSRMVPSRSAQRL
What is the function of this protein?
Modulates pharyngeal pumping activity, at least in part by regulating expression of the acetylcholinesterase genes ace-1 and ace-2 (PubMed:11896189, PubMed:15355315).
What are the official names of this protein?
Protein Fe65 homolog.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton.
Protein: ETV2_MOUSE
Sequence: MDLWNWDEASLQEVPPGDKLTGLGAEFGFYFPEVALQEDTPITPMNVEGCWKGFPELDWNPALPHEDVPFQAEPVAHPLPWSRDWTDLGCNTSDPWSCASQTPGPAPPGTSPSPFVGFEGATGQNPATSAGGVPSWSHPPAAWSTTSWDCSVGPSGATYWDNGLGGEAHEDYKMSWGGSAGSDYTTTWNTGLQDCSIPFEGHQSPAFTTPSKSNKQSDRATLTRYSKTNHRGPIQLWQFLLELLHDGARSSCIRWTGNSREFQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYYRRDIVLKSGGRKYTYRFGGRVPVLAYQDDMGHLPGAEGQ
What is the function of this protein?
Binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.
What are the official names of this protein?
ETS translocation variant 2, Ets-related protein 71.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PCPR_SPHCR
Sequence: MNDSVLPLGHLMVFDALYRHGSAGKAAHALSMPQPTLSRWLAQLRTHFDDPLFVRTRSGMEPTPLAARAAPHIAEMIAIYRQHVRSELRFDPGTSNRNFRIAASDFGQALMLPRLYATLEETAPQVRVTGVNLRHGPLVEELESGSIDIAFGGFPTLSAGIKTQTLFREEYVCVMRQSHPALTHGLDLEAFRQCRHIIVTAHEFNHVHEQVEARLLELLPPESIRFTTENFLVSAVIAEETDVILTIPSRLARWFANRGGLTIFPVPIELPSIEVKQYWHERYDKDPGNIWLRRVIAKIGFQNPPAE
What is the function of this protein?
Transcriptional activator for the pcpA, pcpB and pcpE genes for pentachlorophenol (PCP) degradation.  Essential for PCP degradation.
What are the official names of this protein?
PCP degradation transcriptional activation protein.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: Y039_METKA
Sequence: MAVERVSTGIPGMDEVLNGGIPERNAVLLTGGPGTGKTIFSQQFIWAGLEEGEPGVFVTLEEHPVQVRKNVEGFGWNFREYEEEGLLAVVDAFTGGIGRASEYEKYVVKDPTDASELIGVIRQAVNDVEAKRVAIDSVTPLYIDKPSVARRIMFRLKRMLAGLGCTSILVNQIAAHERGFGGPGVEHAVDGIIRLDLDEVEGRLWRSLIVWKMRGTAHSMRRHPFEITDEGIRVDPEKVFVKERGEVREVED
What are the official names of this protein?
UPF0273 protein MK0039.
What is the protein family that this protein belongs to?
Belongs to the UPF0273 family.
Protein: IF5A_SULIL
Sequence: MSITYTTVGELKVGSYVVIDGEPCRVVEVTKAKTGKHGSAKANVVAIGVFSGAKKTLMAPVDQQVEVPIIEKHIGQIIADMDDKIQVMDLETYETFEIEKPTEDELASKIRPNAELEYWEIMGRRKIVRVK
What is the function of this protein?
Functions by promoting the formation of the first peptide bond.
What are the official names of this protein?
Translation initiation factor 5A, Hypusine-containing protein, eIF-5A.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CITD2_SALPA
Sequence: MKIIKDALAGTLESSDVMIRIGPSSEPGIRLELESLVKQQFGAAIEQVVRETLAKLGVERALVSVDDKGALECILRARVQAAALRAAEQTEIQWSAL
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein 2, Citrate lyase gamma chain 2.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAN_METM5
Sequence: MSYPDDYSTDIEKNKMDLKEFKEKTQIAELESKVLRLELKNKDISRENVQIKKENEILKRELDKLRIPPLILGTILDRVNERKAVVKSSTGPNFLVNLSQFVDPDDIVPGARVCLNQQTLAIVEVLPKEKDYRAMAMEIEEKPDISFEDIGGLNNQIRDIKEVVELPLKNPELFEKVGIVPPKGVLLYGPPGTGKTLLAKAVAYETNASFVRVVGSELVKKFIGEGAKLVRDVFKLAKEKSPCIIFIDEIDAVASKRTESLTGGDREVQRTLMQLLAEMDGFDSRGDVKIIAATNRPDILDPAILRPGRFDRIIEISMPDEDGRLDILKIHTEKMNLKGVDLREVAKIAENMVGADLKAVCTEAGMFAIREEREFIKMDDFREAITKITGKKEKCSYDMPQLTVMYG
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle.  Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.  Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
What are the official names of this protein?
Proteasome-activating nucleotidase, PAN, Proteasomal ATPase, Proteasome regulatory ATPase, Proteasome regulatory particle.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_SACS2
Sequence: MNEIIPSIDISFGKAVKRIRGVRGTGLVLGNPIELANKLYNEGYSRIHVVDLDAAEGVGNNEMYIKEICKIGFDWIQVGGGIRDVEKAKRLISLDVNALIFSTIVFTNFNLFYNIVREIGNNRVIVSIDYDDTKRVLISGWKERSMEIIDGIKKVNELELLGIILTYVTNEGTVKGIDYSVKDYAKLIRGVKEYAGGVSSDSDITFLKNVGFDYIIVGMAFYLNKIRGTNVV
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: E2FE_ARATH
Sequence: MSDLSPERFKLAVTSPSSIPESSSALQLHHSYSRKQKSLGLLCTNFLALYNREGIEMVGLDDAASKLGVERRRIYDIVNVLESVGVLTRRAKNQYTWKGFSAIPGALKELQEEGVKDTFHRFYVNENVKGSDDEDDDEESSQPHSSSQTDSSKPGSLPQSSDPSKIDNRREKSLGLLTQNFIKLFICSEAIRIISLDDAAKLLLGDAHNTSIMRTKVRRLYDIANVLSSMNLIEKTHTLDSRKPAFKWLGYNGEPTFTLSSDLLQLESRKRAFGTDITNVNVKRSKSSSSSQENATERRLKMKKHSTPESSYNKSFDVHESRHGSRGGYHFGPFAPGTGTYPTAGLEDNSRRAFDVENLDSDYRPSYQNQVLKDLFSHYMDAWKTWFSEVTQENPLPNTSQHR
What is the function of this protein?
Inhibitor of E2F-dependent activation of gene expression.  Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers.  Controls the timing of endocycle onset and inhibits endoreduplication.
What are the official names of this protein?
E2F transcription factor-like E2FE, DP-E2F-like protein 1, E2F-like repressor E2L3.
What is the protein family that this protein belongs to?
Belongs to the E2F/DP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RFNG_CHICK
Sequence: MNSSCLGLRRTCFLLSVTAAAVLLLLLPRGQPPAAPRRRPPPAGPSRPSPKREARPAGSDVPGDRGGGSGAAGGGRGVAGSPWPSRRVRMGPPGGSAKESLELKDIFIAVKTTRKYHKTRLELLFQTWISRARGQTFIFTDWEDRELRLKAGDHMINTNCSAVHTRQALCCKMSVEYDKFLESGQKWFCHVDDDNYVNPRTLLRLLSAFSPSQDVYVGRPSLDHPIEAADHVQSDGSKTSVKFWFATGGAGFCISRGLALKMSPWASLGNFISTAERVRLPDDCTIGYIIEGLLEVKLLHSPLFHSHLENLQRLQGESVLQQVTLSYGDPENKHNVVSVGGVFGLQQDPTRFKSVHCLLYPDTIWCPNKKMS
What is the function of this protein?
Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules (By similarity).  Plays an important role in limb outgrowth, it directs the formation and positioning of the apical ectodermal ridge (AER), one of the key organizer centers of vertebrate limb development (PubMed:9121551, PubMed:9121552).
What are the official names of this protein?
Beta-1,3-N-acetylglucosaminyltransferase radical fringe, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: CLPP_CARHZ
Sequence: MSYLVPIVIEQTSRGERSYDIWSRLLKDRTIFIGGPIDDHVANLVIAQMLFLEAEDPEKDIHLYINSPGGVITAGMAIYDTMQYIKPDVSTICIGQAASMGAFLLAAGAKGKRFSLPYARIMIHQPLGGVQGQATDIDIHAREILRMRDMLNELLTKHTGQPKEKIERDTERDFFMSAAEAKEYGIIDEVITVRK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FSTL1_MOUSE
Sequence: MWKRWLALSLVTIALVHGEEEPRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCKPHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKEKKSASPSASPVVCYQANRDELRRRLIQWLEAEIIPDGWFSKGSNYSEILDKYFKSFDNGDSHLDSSEFLKFVEQNETAINITTYADQENNKLLRSLCVDALIELSDENADWKLSFQEFLKCLNPSFNPPEKKCALEDETYADGAETEVDCNRCVCSCGHWVCTAMTCDGKNQKGVQTHTEEEKTGYVQELQKHQGTAEKTKKVNTKEI
What is the function of this protein?
Secreted glycoprotein that is involved in various physiological processes, such as angiogenesis, regulation of the immune response, cell proliferation and differentiation (By similarity).  Plays a role in the development of the central nervous system, skeletal system, lungs, and ureter (PubMed:21826198, PubMed:19595790).  Promotes endothelial cell survival, migration and differentiation into network structures in an AKT-dependent manner.  Also promotes survival of cardiac myocytes (PubMed:20054002).  Initiates various signaling cascades by activating different receptors on the cell surface such as DIP2A, TLR4 or BMP receptors (By similarity).
What are the official names of this protein?
Follistatin-related protein 1, Follistatin-like protein 1, TGF-beta-inducible protein TSC-36.
What are the subcellular locations of this protein?
Secreted.
Protein: RLME_PELUB
Sequence: MKKNRISKNWINKQKRDIYVRQSQVDGYRARSAYKLIEIDEKFKIFKNGISVIDLGASPGSWSQYISRTVKSGRLVSIDLKGMEEIENTIQIKGDFTDLESQEKIKALFKSKVDVVVSDMAVNTTGIKDIDAIYTGELAMEAMNFSKEMLVKEGRFVSKIFLGSSFNEIVALGKKLFKEVKVFKPKSSRKESKESFIICKILR
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GADH1_PANCY
Sequence: MERGERVSVPVSGYSRGEGVTVANELKKVDAVVVGFGWAGAIMAKELTEAGLNVVALERGPHRDTYPDGAYPQSIDELTYNIRKKLFQDLSKSTVTIRHDASQTAVPYRQLAAFLPGTGTGGAGLHWSGVHFRVDPVELNLRSHYEARYGKNFIPEGMTIQDFGVSYNELEPFFDQAEKVFGTSGSAWTIKGKMIGKEKGGNFYAPDRSSDFPLPAQKRTYSAQLFAQAAESVGYHPYDMPSANTSGPYTNTYGAQMGPCNFCGYCSGYACYMYSKASPNVNILPALRQEPKFELRNNAYVLRVNLTGDKKRATGVTYLDGQGREVVQPADLVILSAFQFHNVHLMLLSGIGQPYNPITNEGVVGRNFAYQNISTLKALFDKNTTTNPFIGAGGAGVAVDDFNADNFDHGPYGFVGGSPFWVNQAGTKPVSGLPTPKGTPNWGSQWKAAVADTYNHHISMDAHGAHQSYRANYLDLDPNYKNVYGQPLLRMTFDWQDNDIRMAQFMVGKMRKITEAMNPKMIIGGAKGPGTHFDTTVYQTTHMSGGAIMGEDPKTSAVNRYLQSWDVPNVFVPGASAFPQGLGYNPTGMVAALTYWSAKAIREQYLKNPGPLVQA
What is the function of this protein?
Part of the heterotrimer that catalyzes the conversion of D-gluconate to 2-dehydro-D-gluconate.  This subunit functions as the dehydrogenase.
What are the official names of this protein?
Gluconate 2-dehydrogenase flavoprotein, GA 2-DH dehydrogenase subunit, GADH dehydrogenase subunit.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Periplasmic side.
Protein: SURE_THEP3
Sequence: MKILLTNDDGVQGLGMLKLAEYLKDKYKVTVVAPEKERSAISHAITLHKPLRLKKVKEEDSLKIYAINGTPSDCVKLGIEVVLREKPDIVISGINEGLNLGTDILYSGTVSAAIEAAIYGIPAIAVSRAETADIEDRRIYKFLENLIEKVLEKGLPKNTLLNVNIPDFKKGIKGVKATILGKSIYIETFQKNYDPRGKEYYWMAGKISEIEKDERTDIVSVKEGYISITPIHFDLTEYNMINILNSWDIKIE
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OR3A3_HUMAN
Sequence: MSLQKLMEPEAGTNRTAVAEFILLGLVQTEEMQPVVFVLLLFAYLVTTGGNLSILAAVLVEPKLHAPMYFFLGNLSVLDVGCITVTVPAMLGRLLSHKSTISYDACLSQLFFFHLLAGMDCFLLTAMAYDRLLAICQPLTYSTRMSQTVQRMLVAASWACAFTNALTHTVAMSTLNFCGPNEVNHFYCDLPQLFQLSCSSTQLNELLLFVAAAFMAVAPLVFISVSYAHVVAAVLQIRSAEGRKKAFSTCGSHLTVVGIFYGTGVFSYMRLGSVESSDKDKGVGVFMTVINPMLNPLIYSLRNTDVQGALCQLLVGKRSLT
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 3A3, Olfactory receptor 17-201, OR17-201, Olfactory receptor 3A6, Olfactory receptor 3A7, Olfactory receptor 3A8, Olfactory receptor OR17-22.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SSRG_HUMAN
Sequence: MAPKGSSKQQSEEDLLLQDFSRNLSAKSSALFFGNAFIVSAIPIWLYWRIWHMDLIQSAVLYSVMTLVSTYLVAFAYKNVKFVLKHKVAQKREDAVSKEVTRKLSEADNRKMSRKEKDERILWKKNEVADYEATTFSIFYNNTLFLVVVIVASFFILKNFNPTVNYILSISASSGLIALLSTGSK
What is the function of this protein?
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
What are the official names of this protein?
Translocon-associated protein subunit gamma, TRAP-gamma, Signal sequence receptor subunit gamma, SSR-gamma.
What is the protein family that this protein belongs to?
Belongs to the TRAP-gamma family.