PharMolix/UniProtQA huggingface dataset:
Protein: MNMG_EHRCR
Sequence: MDHYDVVVIGGGHAGCEAAAAAARIGAKTLLITHSTSTIGEMSCNPAIGGIAKGTVVREVDALDGLMGKVIDKASINSSILNRSKGPAVWGPRAQADRKIYKNTMQDIILNYPNLTVLEASVEDFTITEKDEKFTVETVITSDQQVIYTKKLILTTGTFLQGTIHIGSYNTPAGRFGEQPSIGLAKTLEKYNFKLGRLRTGTPPRLDINSINFSGLQEQKGDSEPSPFSYMSQSIDLPQISCYLTATNTRTHEVIKNNLHRAAASNSLKDIKAPRYCPSIEEKVRRFSERNSHQVFLEPEGLDSNIIYPNGITTSSPLDVQYEMLKTIPGLEKVNIIRSGYSVEYNFIDPRELYHTLETKKISGLYFAGQINGTTGYEEAAGQGIIAGINAALSLNSKYEPFILKRSDAYIGVMIDDLVTLGTSEPYRLFTSRAEYRLRLRSDNADLRLTELGYQISVVSSKRYTILKNKKQEIITLTNILKNIITTPTQLARHNIPISQDGVRRSIFDLLGHPNINMEIVSRICNTVKEFNKNVAEQVAIEAKYAPYFDRQDADIKAFLEEENTHIPHNIEFSQIHGLSKEIQEKLEYIKPLSIGSARRIPGITPAAITNILIYLRYYKSKKTS
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOC_STRPI
Sequence: MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVEHAKKGLEGTDAKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNLALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGGATIADVRLMCETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADGDY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURB_BRUO2
Sequence: MMESGEALLKKLDGRLSGLRGRLTPDTGMDKITWFRAGGPAQVLFQPSDEEDLSAFLKAVPEEIPLLVVGIGSNLLVRDGGVPGFVVRLSAKGFGEVEQVCDTQLRAGAAAPDKRVAAAALEAGLAGFHFYHGIPGGIGGALRMNAGANGVETRERVVEVRALDRKGEVHVLSNADMGYAYRHSSASPDLIFTSVLFEGVPGERDDIRRAMDEVQHHRETVQPVREKTGGSTFKNPEGTSAWKEIDKAGCRGLRVGGAQMSEMHCNFMINTGNATGHDLETLGETVRARVFENSGIRLHWEIKRLGLFREGEQIEEFLGKIV
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXOD_RHIME
Sequence: MVCQARFGVKNASRGHRMERPQTVKGKIMAVEFGDSQRSLSDTLTGMIASIRGNTITLRELMIEIGEQGFLLLCALLTLPFLIPVSIPGVSTVFGAAIILISLAITLNRMPWLPKRILDREIATEKLVPTLRKGAALVSKLDRYVRPRLNFLTEGALMNRFNGLMIMAGGVLLMFPLGLIPLSNTLPGIAILLLSLGIIQRDGLMVAGGYFFLVATTVYFAVLGYAAFAAGQGLSHFFVS
What is the function of this protein?
Required for nodule invasion.  Mutations in this gene lead to sensitivity to alkaline conditions which prevents nodule invasion.
What are the official names of this protein?
Protein ExoD.
What is the protein family that this protein belongs to?
To Synechocystis PCC 6803 slr1875.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GPX2_HUMAN
Sequence: MAFIAKSFYDLSAISLDGEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRFPRRLVVLGFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLKDKLPYPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIEPDIKRLLKVAI
What is the function of this protein?
Could play a major role in protecting mammals from the toxicity of ingested organic hydroperoxides (PubMed:8428933).  Tert-butyl hydroperoxide, cumene hydroperoxide and linoleic acid hydroperoxide but not phosphatidycholine hydroperoxide, can act as acceptors (PubMed:8428933).
What are the official names of this protein?
Glutathione peroxidase 2, GPx-2, GSHPx-2, Gastrointestinal glutathione peroxidase, Glutathione peroxidase-gastrointestinal, GPx-GI, GSHPx-GI, Glutathione peroxidase-related protein 2, GPRP-2.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: PLA2R_BOVIN
Sequence: MPLLSLSLLLLLLQVPAGSAETAAWAVTPERLREWQDKGIFIIQSENLEKCIQASKSTLTLENCKPPNKYMLWKWVSNHRLFNIGGSGCLGLNVSSPEQPLSIYECDSTHVSLKWHCNKKTITGPLQYLVQVKQDNTLVASRKYLHKWVSYMSGGGGICDYLHKDLYTIKGNAHGTPCMFPFQYNQQWHHECTREGREDNLLWCATTSRYERDEKWGFCPDPTSTEVGCDAVWEKDLHSRICYQFNLLSSLSWSEAHSSCQMQGAALLSIADETEENFVRKHLGSEAVEVWMGLNQLDEDAGWQWSDRTPLNYLNWKPEINFEPFVEYHCGTFNAFMPKAWKSRDCESTLPYVCKKYLNPTDHGVVEKDAWKYYATHCEPGWNPHNRNCYKLQKEKKTWNEALQSCQSNNSVLTDITSLAEVEFLVTLLGDENASETWIGLSSHKIPVSFEWSNGSSVTFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEETLFYLCKKTGLVLSDTESGCQKGWERHGKFCYKIDTVLRSFDHASSGYYCPPALITITSRFEQAFITSLISSVVKTKDTYFWIALQDQNNTGEYTWKTAGQQLEPVKYTHWNTRQPRYSGGCVVMRGRSHPGRWEVRDCRHFKAMSLCKQPVENREKTKQEEGWPFHPCYLDWESEPGLASCFKVFHSEKVLMKRTWRQAEEFCEEFGAHLASFAHIEEENFVNELLHSKFNRTEERQFWIGFNKRNPLNAGSWEWSDGTPVVSSFLDNSYFGEDARNCAVYKANKTLLPSYCGSKREWICKIPRDVRPKVPPWYQYDAPWLFYQDAEYLFHISASEWSSFEFVCGWLRSDILTIHSAHEQEFIHSKIRALSKYGVNWWIGLREERASDEFRWRDGSPVIYQNWDKGKERSMGLNESQRCGFISSITGLWASEECSISMPSICKRKKVWVIEKKKDIPKQHGTCPKGWLYFDYKCLLLKIPEGPSDWKNWTSAQDFCVEEGGTLVAIENEVEQAFITMNLFGHTTNVWIGLQDDDYEKWLNGRPVSYSNWSPFDTKNIPNHNTTEVQKRIPLCGLLSNNPNFHFTGKWYFEDCREGYGFVCEKMQDASGHSINTSDMYPIPNTLEYGNRTYKIINANMTWYTALKTCLMHGAELASITDQYHQSFLTVILNRVGYAHWIGLFTEDNGLSFDWSDGTKSSFTFWKDDESSFLGDCVFADTSGRWSSTACESYLQGAICQVPTETRLSGRLELCSETSIPWIKFKSNCYSFSTVLESTSFEAAHEFCKKKGSNLLTIKDEAENSFLLEELLAFRSSVQMIWLNAQFDGDNETIKWFDGTPTDQSNWGIRKPEVYHFKPHLCVALRIPEGVWQLSSCQDKKGFICKMEADIHTVKKHPGKGPSHSVIPLTVALTLLVILAISTLSFCMYKHSHIIFGRLAQFRNPYYPSANFSTVHLEENILISDLEKNDQ
What is the function of this protein?
Receptor for secretory phospholipase A2 (sPLA2).  Also able to bind to snake PA2-like toxins.  Although its precise function remains unclear, binding of sPLA2 to its receptor participates in both positive and negative regulation of sPLA2 functions as well as clearance of sPLA2.  Binding of sPLA2-IB/PLA2G1B induces various effects depending on the cell type, such as activation of the mitogen-activated protein kinase (MAPK) cascade to induce cell proliferation, the production of lipid mediators, selective release of arachidonic acid in bone marrow-derived mast cells.  In neutrophils, binding of sPLA2-IB/PLA2G1B can activate p38 MAPK to stimulate elastase release and cell adhesion.  May be involved in responses in pro-inflammatory cytokine productions during endotoxic shock.  Also has endocytic properties and rapidly internalizes sPLA2 ligands, which is particularly important for the clearance of extracellular sPLA2s to protect their potent enzymatic activities.  The soluble secretory phospholipase A2 receptor form is circulating and acts as a negative regulator of sPLA2 functions by blocking the biological functions of sPLA2-IB/PLA2G1B and sPLA2-X/PLA2G10.
What are the official names of this protein?
Secretory phospholipase A2 receptor, PLA2-R, PLA2R, 180 kDa secretory phospholipase A2 receptor, M-type receptor.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Soluble secretory phospholipase A2 receptor]: Secreted.
Protein: IF1A_PYRAE
Sequence: MARLRIINFYRSAYCSAMSEFRLPGEGEILGKVIEMLGDGRFKVICADGQIRVARLPGRLRRRLWLKAGDYVIVALWDFDREKGDIVHKYEKRDVEELKRRGFAEAIEALDSYA
What is the function of this protein?
Seems to be required for maximal rate of protein biosynthesis.  Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).
What are the official names of this protein?
Translation initiation factor 1A, aIF-1A.
What is the protein family that this protein belongs to?
Belongs to the eIF-1A family.
Protein: T61_TERAN
Sequence: MATSGRLLCLCLVLGLVFESLGHPGARLPKDGKRAVSTRHAHDDPFAHEVNCGGFPCMFSCCENDVCMELNCEYFPSLGQ
What are the official names of this protein?
Teretoxin Tan6.1.
What is the protein family that this protein belongs to?
Belongs to the teretoxin M (TM) superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MGSA_ECOLI
Sequence: MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQRYLADRLK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MET23_HUMAN
Sequence: MYVWPCAVVLAQYLWFHRRSLPGKAILEIGAGVSLPGILAAKCGAEVILSDSSELPHCLEVCRQSCQMNNLPHLQVVGLTWGHISWDLLALPPQDIILASDVFFEPEDFEDILATIYFLMHKNPKVQLWSTYQVRSADWSLEALLYKWDMKCVHIPLESFDADKEDIAESTLPGRHTVEMLVISFAKDSL
What is the function of this protein?
Histone methyltransferase that dimethylates histone H3 at 'Arg-17', forming asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling (By similarity).  Maternal factor involved in epigenetic chromatin reprogramming of the paternal genome in the zygote: mediates H3R17me2a, promoting histone H3. 3 incorporation in the male pronucleus, leading to TET3 recruitment and subsequent DNA demethylation (By similarity).
What are the official names of this protein?
Histone-arginine methyltransferase METTL23, Methyltransferase-like protein 23.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL23 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localizes in male and female zygote pronucleus and cytoplasm.
Protein: UTP10_COCIM
Sequence: MASSLAAQLAQIAATSTHQLDLKAQRAAHSQSLIFEKKIAGSQDFDTIFQVCHEGFQELCSLDSRFLSFRRNIFSDQSKTEDRGQMTTSQNKELDSVLEDFLSLVGARLLLTPAVKAVDWLIRRFRVHEYNTSFLLLTFLPYHTTPLFLNFLSILPEDLTQTFKVFLPYKRSMTLPPRQVIVQSASTNKSFFSALNNYVLQVSKSQAHYQGLVSFWAGITTEALANMLDSAKSGRMEIETRNKEDVLIRILPVLNDAFMLRKAPQLVVGCYMLCVVLANKASLEDHVLDNLMEAVTGSWTQTNFVSGITCLSVLSQQKHEKSLPSKVVKAVLRLDNVIEVFEELSGRYAVTGLIIGLIRSCVQENGKRSDPARIPFVGQLIQRAILSDSETIEALTILLQAFSDLQRQGLVADGMGKQLSDLLLQFNESDTLAPLLRKAIENAGVDITQLEMTLETVLQADIMPMEIEDADLLDFISSSQTQDAFAVALEPLSQAAITESSFLAPGSSLLFDQLAEAFIHGASTKDRVSRFIKLPVLRPDKPLDDPLYLSFFIRFFSGPYPVTARTVAISIVSSCITAMADKSADMQGILPYIISALADPSERVRREAAALLSLIDRLASKCKDNDDSNAQIWGRGCLYGQNERSESVQFLPMKDIYKIIHHALMPALEEYVLDPDQVGRTLTQVIRGPRSQDDSDRTRSESTGVEFKKPLRRDLFLFLCSHASKTALYTVKLRLLKFLNKVGKIGSLNCTEALRQVFDQWRLLSLEHLQRIEDGERISTNELEDQVLSIIYPKDMDAVDLLFSSLTSNSRSNRESFLTAGFNRLKEVWPSLEETHELSLANRLLQISLSLENGKLAGAAKGLLRSVDLSGPVILEFLNKISASVPDLGSRGPPSKKRRTSQNNMVPMSSMDKETDSVLQKMTFILELIDSSHSENHPELISGLFQTLTIIHHLKLQTRSEMSYLLSLNLGILLSIVNKWKGMPTRKINTSSIRADLIIDCVRTSESPQVQNTALLLVAGLATVAPELVLHSVMPIFTFMGSSVLRKDDEYSALVIDQTIDQVVPPLVQSLRNQKRDVVSGTSELLLSFTTAFEHIPSYRRLRLFEALITKLGPEDFLFAVFAMFANRYSMDKDVLATMTALASDCNAELQLITYARYLNLVKDTLQPKPTLAKTLLGVGSEDGRDPQKIAVDLLQALSHLLKFTSLRTKMSECFDSGTEQQVDKAHGLFSTILEQTLALSESVRTVKPVNSACGETLGTLLGTLSLVDFVDTIEVLLQRPSDDLRRKVIKLLENRLDSSNDRDKASQARVLSFLTVLINILETSPDILLKHAAVACIEKIGEKYGKKDPSQVLAAAKVISGEHCLGQPDRRIRVMGLLCLASMSEILGEGIIPTLPEALPRAIDLLRDTLAASDDDSQLHDAVYSLISALLIHVPWMISGEYLDNILQLSFISSNTDLAEGSDENRLEALQLLAKRVDVKEAFAGVERNWDSAVTQGSRAVQEALDVVRTAIEKHAKSATVKNVSVLMKLLCKAFDLRRLQLSPLNDGGFDEAEVDEIESRANDVAVRMIYKLNDTVFRPLFIDLTAWAVSGLGKKDTTGRVARLTTFYRFLESFFGTLKSIVTGYSSYIIESAVEVLKFSRCNDKATKTLWLAVLRMLRNSFGHDQDEFWQSPTHLASISEPLIKQLSMATNSPTLDLVAAEAIPTIVELAVAADSPDNHKELNTVIMKFMRAGHGNARGADNPYTRLAAVKCEQQLTERLGEEWLALLPEMLPYISELLEDDDENVEREVRRWVLSIEDILGEKLDDMLT
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA.  Involved in ribosome biosynthesis (By similarity).
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 10.
What is the protein family that this protein belongs to?
Belongs to the HEATR1/UTP10 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PYRH_TROW8
Sequence: MASRRVLLKLSGESFGGGAPLVDPDVVSAIASEIVRVSKTIQIAIVVGGGNYFRGAELSRRGMARDRADYMGMLGTVINALALQDFLEQAGGDTRVQSAISMSQVAELYVPRRAERHLTKGRVVIFAAGAGMPYFSTDTVAVQRALEIKADIVLIAKNGVDGVYTDDPQINPNAKKIYKITYREALERGLRVVDSAALGLCMEHGLPMRVFGMESLRDAVSGLKVGTELSQ
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSME3_MOUSE
Sequence: MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAETLY
What is the function of this protein?
Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome.  11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits.  Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage.  May also be involved in cell cycle regulation.  Mediates CCAR2 and CHEK2-dependent SIRT1 inhibition (By similarity).
What are the official names of this protein?
Proteasome activator complex subunit 3, 11S regulator complex subunit gamma, REG-gamma, Activator of multicatalytic protease subunit 3, Ki nuclear autoantigen, Proteasome activator 28 subunit gamma, PA28g, PA28gamma.
What is the protein family that this protein belongs to?
Belongs to the PA28 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localizes to the cytoplasm during mitosis following nuclear envelope breakdown at this distinct stage of the cell cycle which allows its interaction with MAP3K3 kinase.
Protein: RL3_ECO5E
Sequence: MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDGYRAIQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEFTVGQSISVELFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGQMGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSDLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: Y3481_MYCA1
Sequence: MSGHSKWATTKHKKAVIDARRGKMFARLIKNIEVAARVGGGDPAGNPTLYDAIQKAKKSSVPNENIERARKRGAGEEAGGADWQTITYEGYAPNGVAVLIECLTDNRNRAASEVRVAMTRNGGTMADPGSVSYLFSRKGVVTCEKNGLTEDDILAAVLDAGAEEVEDLGDSFEIICEPTDLVAVRTALQDAGIDYDSAEAGFQPSVTVPLDADGAQKVMRLVDALEDSDDVQDVWTNADIPDEILAQIEE
What are the official names of this protein?
Probable transcriptional regulatory protein MAV_3481.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_XYLFT
Sequence: MSEDRQSRSGDGNKILYCSFCGKSQREVRKLIAGPSVFICDECVELCNDIIREELEEKSQSARSSLPKPKEILEVLDQYVIGQQRAKRTLAVAVYNHYKRIESRHKNDDIELAKSNILLVGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVENIIQKLLHKCDYDVEKAQHGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTKNILFICGGAFAGLDKVIQQRCNEVGGIGFGVKVKSSESKRDVGKVLAGVEPEDLIKFGLIPEFVGRLPVVATLDELDESALVKILTEPKNAITKQFKKLFEMENVELEFRQDALSAVARKALKRKTGARGLRTIVELVLLDTMYELPSQEGISKVVVDESVIENKSEPYLIYQTMPAKVASGE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: MSH2_DICDI
Sequence: MSDNEQEESSQVVLKEDKTFVTFFQSLVSSNEDTDTIRLFDRKGYYSIHGEDAVFVAMMHFKSKKSLKYWSISDPNPKKKIKIDNDGSLTTTASSSQQQQQELGLAVLTIRQGYEFENIVKELLDEKKKIEIWSMKPNSKQQWELIKKGSPGNTQMFEDVLLNGNCEGSVMMALKVTREKGSIVFGISFGDATFKTIGVSQFMDNDNLSNLSSFIMQMSVKECLLCCDQKNYDYQKVKEKLSDAGIPFTELPKSDFSSKNAEQDLTRLLGSVKNNLPDIEQEHAIQSASCLIKHLDLLSNPNYFGKFKLEKYDLDRYMKLDSSSFKGLHIIDLKDSSVSAAAGGGGAGGASSSSNKDQSLYNLLNQCNTPMGSRLLLQWVKQPLLNAEEIEARLNFVEAFYNDLELRQSLRSNDLKKIGDLDRLSKKLHGQKATLEDCVNLYGIVTRLPVVLQSLNNHSSIHQELIKVNFIESLESIISDFAKFCAMVEKTIDLDLANDKHEYVIRSSFDETLRGIQLKKDQISNKIERFRVDIADDLNLDEAKVKLHYSEKDMFLLRISRKDEVAIRDKKKYIVHATAKDGVRFATREIDTLNEAYKKWSAEYLDKQDGLAKRTLQIAASFVPLIEDLSSLIATLDVFVTLSHVSSIAPIPFIRPEIIPLGSDENGAGTVIIGGRHPCVEIQDNVNFIANDIDLTRGQSQFQIITGPNMGGKSTFIRQVGLIVLMAQIGCFVPAQKATIAVVDCILSRVGAGDSQLRGVSTFMAEMLETSYILKVATKNSLIIIDELGRGTSTYDGFGLAWGIAEYICNQIGGFCLFATHFHELTILSDLLPMVKNLHVSASTQNNTFTLLYKVEQGPCDQSFGIHVAILANFPSQVIENAKQKAKELESFESNTLKQNHNKFLEEFKEINFNSNDVEKSLSLVNSLLNKYSIDIN
What is the function of this protein?
Component of the post-replicative DNA mismatch repair system (MMR).  Forms two different heterodimers: MutS alpha (msh2-msh6 heterodimer) and MutS beta (msh2-msh3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair.  When bound, heterodimers bend the DNA helix.  MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA.  MutS beta recognizes larger insertion-deletion loops.  After mismatch binding, MutS alpha or beta forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.  ATP binding and hydrolysis play a pivotal role in mismatch repair functions.  The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone.  This transition is crucial for mismatch repair.  MutS alpha may also play a role in DNA homologous recombination repair (By similarity).
What are the official names of this protein?
DNA mismatch repair protein Msh2, MutS protein homolog 2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL7_COREF
Sequence: MAKLTKDELIEAFKEMTLIELSEFVKEFEEVFEVTAAAPVAVAAAGAAGGEAAAAEEKDEFDVVLEDAGAKKIGVIKVVRELVSGLGLKEAKELVEGAPKAILEGANKDDAEAAKAKLEEAGAKVTLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: THNA_PHOLI
Sequence: KSCCPSTTARNIYNTCRLTGTSRPTCASLSGCKIISGSTCBSGWBH
What is the function of this protein?
Thionins are small plant proteins which are toxic to animal cells.  They seem to exert their toxic effect at the level of the cell membrane.  Their precise function is not known.
What are the official names of this protein?
Ligatoxin-A.
What is the protein family that this protein belongs to?
Belongs to the plant thionin (TC 1.C.44) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSAA_VITVI
Sequence: MIIRSPEPEVKILVDRDPIKTSFEEWARPGHFSRTIAKGPDTTTWIWNLHADAHDFDSHTSDLEEISRKVFSAHFGQLSIIFLWLSGMYFHGARFSNYEAWLSDPTHIGPSAQVVWPIVGQEILNGDVGGGFRGIQITSGFFQMWRASGITNELQLYCTAIGALVFAALMLFAGWFHYHKAAPKLAWFQDVESMLNHHLAGLLGLGSLSWAGHQVHVSLPINQFLNAGVDPKEIPLPHEFILNRDLLAQLYPSFAEGATPFFTLNWSKYAEFLTFRGGLDPVTGGLWLTDIAHHHLAIAILFLIAGHMYRTNWGIGHGLKDILEAHKGPFTGQGHKGLYEILTTSWHAQLSLNLAMLGSLTIVVAHHMYSMPPYPYLATDYGTQLSLFTHHMWIGGFLIVGAAAHAAIFMVRDYDPTTRYNDLLDRVLRHRDAIISHLNWACIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPVFAQWIQNTHALAPSATAPGATTSTSLTWGGGDLVAVGGKVALLPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNSISVVIFHFSWKMQSDVWGSISDQGVLTHITGGNFAQSSITINGWLRDFLWAQASQVIQSYGSSLSAYGLFFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPATQPRALSIVQGRAVGVTHYLLGGIATTWAFFLARIIAVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: Y578_METJA
Sequence: MDYLGIIMKIAIISGKGGVGKSSISTSLAKLFSKEFNIVALDCDVDAPNFNLMFDVKDKKLLEVIYREIYEINDDCIRCGKCLDVCQFDAIGDFKINPILCEGCGACELICEFDAIEPIKRESGYIYEGFVGFPLIWGELEVGESGSGKIIEHIKNHAKKYKAELGIIDGPPGVGCPLISTVKDVDLALCIVEPTKSSVNDCLRLIETLNFFNVEYLIVENKKGMNNINYPFKIFHSIPFDFDVPKLIANKILLCDSNSKVSESIKELYEKLKEFI
What are the official names of this protein?
Uncharacterized protein MJ0578.
Protein: NUON_PHOV8
Sequence: MDITAILHMHAELSLTAVFILMFLLDLFLPATQRHWLRPMACILLTIQLLANLWPEEVTLFGGMYHSTPMASVLKSILTIGTILVFLQADTWLKREDTRHKQGEFYILTLSTLLGMYFMVSAGHFLLFFLGLELATVPMACLVAFDKYKGHSAEAGAKFILSALFSSGIFLYGISMIYGTAGTLYFEDIPAGLTGTPLQVLALVFFFSGLAFKLSLVPFHLWTADTYQGAPTTVSAYLSVISKGAAAFALMIILMKVFGPMTEQWSEILCIIIVATITIANLFAIRQNNLKRFMAFSSISQAGYIMLAVLAGTPQDMASLVYYIVVYIAANLAVFGVISTIEQHTHGKIEREDYNGLYKTNPKLTMVMTLALFSLAGIPPFAGFFSKFFVFMAAFHSGYYLIVFIALVNTIISLYYYLLIVKAMFITPNEDPIGNFRTATPMRISLLVCVAGIFVLGIISGVYQLLSDTAIL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CUE6_CONCL
Sequence: MKFLLFLSVALLLTSFIETEAGPVNEAGVERLFRALVGRGCPADCPNTCDSSNKCSPGFPG
What is the function of this protein?
Probable neurotoxin with unknown target.  Possibly targets ion channels.
What are the official names of this protein?
Conotoxin Cal14.6, Conotoxin Cal14.2, Conotoxin Cal14a, Conotoxin Cl14.6, Conotoxin Cl14a.
What are the subcellular locations of this protein?
Secreted.
Protein: DHE4_HYLLA
Sequence: MYCYLGKALLPSGAGPAALGSAGAALLGRARGQPAAAPQPGLALAAWRHYSEVVADRKDDPNFFKMVEGFFDRGASIVEDKLVKDLRTRESEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSADVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTENELEKITRRFTMELAKKGFIGPGIDVPAPDMNTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYVNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEFQDSISGASEKDIVHSALAYTMERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVFKVYSEAGVTFT
What is the function of this protein?
Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission.
What are the official names of this protein?
Glutamate dehydrogenase 2, mitochondrial, GDH 2.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
What are the subcellular locations of this protein?
Mitochondrion matrix.