PharMolix/UniProtQA huggingface dataset:
Protein: SATB2_MOUSE
Sequence: MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVGGLMIPVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLALGYSHSSAAQAQGIIKLGRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLEDLPAEQWNHATVRNALKELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGRWYKKYKKIKVERVERENLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPHSQIHHSTPIRNQVPALQPIMSPGLLSPQLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLNHPPIPRAVKPEPTNSSVEVSPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEILRKEEDPRTASQSLLVNLRAMQNFLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSSSRTPQAKTSTPTTDLPIKVDGANVNITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWLCELLRWKENPSPENRTLWENLCTIRRFLNLPQHERDVIYEEESRHHHSERMQHVVQLPPEPVQVLHRQQSQPTKESSPPREEAPPPPPPTEDSCAKKPRSRTKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTIIKFFQNQRYHVKHHGKLKEHLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENADKSKAAPAETDQR
What is the function of this protein?
Binds to DNA, at nuclear matrix- or scaffold-associated regions.  Thought to recognize the sugar-phosphate structure of double-stranded DNA.  Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling.  Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers.  Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating Bcl11b expression.  Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex.  May play an important role in palate formation.  Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation.
What are the official names of this protein?
DNA-binding protein SATB2, Special AT-rich sequence-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the CUT homeobox family.
What are the subcellular locations of this protein?
Nucleus matrix.
Protein: ARK74_HUMAN
Sequence: MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVKIATKANPWIGNSLKPDSVRSQLETSLKRLQCPRVDLFYLHAPDHSAPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYSATTRQVETELFPCLRHFGLRFYAYNPLAGGLLTGKYKYEDKDGKQPVGRFFGTQWAEIYRNHFWKEHHFEGIALVEKALQAAYGASAPSMTSAALRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEGPLEPAVVDAFNQAWHLFAHECPNYFI
What is the function of this protein?
Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol.  May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen (By similarity).
What are the official names of this protein?
Aflatoxin B1 aldehyde reductase member 4, AFB1 aldehyde reductase 3, AFB1-AR 3, Aldoketoreductase 7-like.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.
Protein: USHA_SALTY
Sequence: MKFLKRGVALALLAAFALTTQPAQAYEKDKTYKITILHTNDHHGHFWRSEYGEYGLAAQKTLVDSIRKEVAQEGGSVLLLSGGDINTGVPESDLQDAEPDFRGMNLIGYDAMAVGNHEFDNPLTVLRQQEKWAKFPFLYANIYQKSTGERLFKPWAIFTRQDIKIAVIGLTTDDTAKIGNPEYFTDIEFRKPAEEAKVVIQELNMNEKPDVIIATTHMGHYDNGDHGSNAPGDVEMARSLPAGSLAMIVGGHSQDPVCMASENKKQVNYVPGTPCAPDKQNGIWIVQAHEWGKYVGRADFEFRNGEMKMVNYQLIPVNLKKKVTWDNGKSERVLYTPEIAENPQMLSLLTPFQNKGKAQLEVKIGSVNGLLEGDRSKVRFVQTNMGRVILAAQIARTGADFGVMSGGGIRDSIEAGDITYKSVLKVQPFGNIVVYADMSGKEVVDYLTAVAQMKPDSGAYPQLANVSFVAKEGKLTDLKIKGEPVDPAKTYRMATLSFNATGGDGYPRIDNKPGYVNTGFIDAEVLKEFIQQNSPLDAAAFTPNGEVSWL
What are the official names of this protein?
Silent protein UshA(0).
What is the protein family that this protein belongs to?
Belongs to the 5'-nucleotidase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MVP_TOMK2
Sequence: MALVVKGKVNINEFIDLSKSEKLLPSMFTPVKSVMVSKVDKIMVHENESLSEVNLLKGVKLIEGGYVCLVGLVVSGEWNLPDNCRGGVSVCMVDKRMERADEATLGSYYTAAAKKRFQFKVVPNYGITTKDAEKNIWQVLVNIKNVKMSAGYCPLSLEFVSVCIVYKNNIKLGLREKVTSVNDGGPMELSEEVVDEFMENVPMSVRLAKFRTKSSKRGPKNNNNLGKGRSGGRPKPKSFDEVEKEFDNLIEDEAETSVADSDSY
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Forms a ribonucleoprotein complex with viral RNA.  Binds microtubules and modulates microtubule stability.  Can bind double-stranded DNA.  Triggers host hypersensitive defense reaction in incompatible plants harboring resistance (R) proteins.
What are the official names of this protein?
Movement protein, 30 kDa protein, Cell-to-cell transport protein.
What is the protein family that this protein belongs to?
Belongs to the tobamovirus movement protein family.
What are the subcellular locations of this protein?
Host cytoplasm, host cytoskeleton. Host cell junction, host plasmodesma. Note=Binds to the host cytoskeleton before being transported to the host plasmodesmata. Observed in virus replication complexes (VRCs) of tobamovirus infected host cells (By similarity). In resistant plants, targeted to the host plasma membrane via the interaction with host resistance (R) protein TM-2 (e.g. tomato ToMV resistance protein TM-2(2), AC Q71BG9) (By similarity).
Protein: NP4_RHOPR
Sequence: MKSYTSLLAVAILCLFGGVNGACTKNAIAQTGFNKDKYFNGDVWYVTDYLDLEPDDVPKRYCAALAAGTASGKLKEALYHYDPKTQDTFYDVSELQVESLGKYTANFKKVDKNGNVKVAVTAGNYYTFTVMYADDSSALIHTCLHKGNKDLGDLYAVLNRNKDAAAGDKVKSAVSAATLEFSKFISTKENNCAYDNDSLKSLLTK
What is the function of this protein?
Heme-based protein that delivers nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation.  Also binds tightly to histamine, which is released by the host to induce wound healing.  NO release is pH dependent and linked to loop dynamics.
What are the official names of this protein?
Nitrophorin-4, NP4, Nitrite dismutase.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Nitrophorin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATG2_YARLI
Sequence: MNWIPNVQKRAFHYVLNRLALFSDLELDNMDISLGTAQKAALTNVKLDPDRVSLPAGMYMRSGKIDEVSVEMRLLGGAGIAVKIDGVHITASMKQMDVETATEHVEEFLERTTADLAASILSEDLSASLQIDPAEEPPLLGMGGSGISEALVKKVTQTVLSQLTVDVTNVHVTLFVAADDKMDLVVDEVRLRPQGGQEMALEVRGVKMKVMDKKARGTSAPVTAGSTAHATTGFTSESDSDSDTDPFSNAKKSLLQSTIFSHEEASSIYMSAIAESANLGFESDPLFGVFYVDTIDVLVFLGEEMRVSCEVGIVRASLDLLPTVILSLVKVGNGGSGGKKSRDSETKEGTAMDLNMSIKSISASICQLGDDWEFKNIDTNLLFSLSDISGSSGAFHKLQIGVCEVKRGSTRVFGFESDEKNTDDEEPTPRDSDILLKASSASFTLVLPKKAVGVFTIPDLIDVVSLITYLLSLIESKQQKAATMTERSERAGASKTTVQTNTFDFDVAGHKLYILPIRLSNGQMSLSRVSFGDVHVKGISFENSIVSVDKVDFDIGLPIVEELHQLLLPIIDAMNSAKNRPVPASVQTAPPKLLRIVEEPVNASSLVINVARVKGKVDLGGKVGVIEVVLGGISVTGPTDRIEISTVEIGRDLSDLGLSKKWLLHPLKRESNVVVELSSGQIQLITVKNCALEFYTELLELFGGKGDDTKAAELQESSSPDSSSRESSSGSESPPKRIPLQIHNCAVGLNPTNSSSSAQFIVKHVTCEIKPSPTFSMTSFIGSASLLLIDDASLVTPNPTDLMSSYLEQYTSVASLTATSISISTSPGNPTCININGDTVTLSTCADSTQTLIHLINSLKPAVELSGAKFQLETLDPFLNTFQDVDDCFFKAKNKDACESSCSSDNDDIDMVSDDVPNNMSFVESYYGGDKPSQSRKSGRQKMAESYTHADFLLDSDLDSLVKRERVRFEEICFEEDYFDKEEEDMPVMSRPRASSHDLASSNELLTPPTVVINIDLIHNIVCNFHDGYDWQYTRNEINGAVDGLKKRMKERPVVEEPPVMTTDLLFNSIYIQAKDEDDLDDVVGEQTEPAKPKEANKSRRGLLSRSSNPLVQVWLQGIACLLTVYAGLEDPDLPPGQVLNSLDVKIKDVEIIDHVPTSTWNKFLTYMRSRGEREAGAVMAHITMQNVKPVSTLSSQEVICHVTILPLRLHVDQDTLDFLTRFFNFKDVRTTAPPDETFIQKFDIRDVPVKLDYKPKKVDYSGLKSGKSTELMNFFILDESDMVLRRIKLRGITGFANLGQKLNDIWMPDVRRTQLPGVLAGVAPVRPLVNLGGGIRNLIVVPVREYKKDGRVVRSLNQGAYAFAKTTTNELVRFGAKLAVGTQNLLEGVVSTERAGESRDLDDSDLESTTKYYTYMGYSDSNNKLISLYANQPLGVYAGLQDAYSSFGKHMNVAKTAIHNLSEDISEADTAGAAAYAVVKAAPVALIRPIIGTTEAVSKTLFGVANEMDPSGRELARDKYKEAN
What is the function of this protein?
Lipid transfer protein required for autophagosome completion and peroxisome degradation.  Tethers the edge of the isolation membrane (IM) to the endoplasmic reticulum (ER) and mediates direct lipid transfer from ER to IM for IM expansion.  ATG2 binds to the ER exit site (ERES), which is the membrane source for autophagosome formation, using basic residues in its N-terminal region (NR) and to the expanding edge of the IM through its C-terminal region.  The latter binding is assisted by an ATG18-PtdIns3P interaction.  ATG2 then extracts phospholipids from the membrane source using its NR and transfers them to ATG9 to the IM through its predicted beta-sheet-rich structure for membrane expansion.
What are the official names of this protein?
Autophagy-related protein 2.
What is the protein family that this protein belongs to?
Belongs to the ATG2 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: RSMH_PARXL
Sequence: MAPAMGNELQHRTVLLEEAVQALVTRADGVYVDGTFGRGGHSRLVLEKLGESGRLIAFDKDPLAIATAQQITDPRFGIVHESFASLRTAMAERGVGRVSGVLLDLGVSSPQVDDPERGFSFRADGPLDMRMDPTRGESAADWLARATVQELTEVIRDYGEERFAFQIAKALVARRAESDRLGPLVSTGELAQIVANVVKTREKGKDPATRTFQAIRIHINQELAELQVVLEAALSLLEQGGRLVVISFHSLEDRIVKRFMQAHASTPAVDRRLPIRAVDLPSPPLKIIGRVFASDAEVAANPRARSAVMRVAERIAP
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1157_DECAR
Sequence: MRLETIRQSMRATGAKDCHIDRVLRAWTQAKPLESGARRHQPENFLPQALRTALPALQEELSALARVRSEHPGEDGSSRLLVELADGQTVESVLLPRDGLCISTQIGCAVGCTFCMTGRDGLLRQVSSAEMVAQVVLGRGRRKVTRVVFMGMGEPSHNMDNVLEAIDTLGTYGGIGHKNLVFSTVGDRRVFDRLPQQRVVPALALSLHSTRAELRAELLPKAPHIDPTELVELAEHYARTTGYPIQYQWTLIDGINDSIEEMDGIVRLLTGKYAIMNLIPYNATATLDYRRPSLEHITTLTKYLHAKGIRTTVRNSAGQDVDGGCGQLRARTLDAGTATDAQKISLKHLKTGTRSAA
What are the official names of this protein?
Probable RNA methyltransferase Daro_1157.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1084_STAHJ
Sequence: MTKKVAIILSNEFEDIELTSPKEAIEEAGFETEIIGDTANAEVVGKHGEKVIVDVSIADAKPEDYDGLLIPGGFSPDHLRGDAEGRYGTFAKYFTKNDVPAFAICHGPQILIDTDDLNGRTLTAVLNVRKDLSNAGANVVDESVVVDKNIVTSRTPDDLDDFNREIVKQLQA
What are the official names of this protein?
Uncharacterized protein SH1084.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family.
Protein: RL1_STAAW
Sequence: MAKKGKKYQEAASKVDRTQHYSVEEAIKLAKETSIANFDASVEVAFRLGIDTRKNDQQIRGAVVLPNGTGKSQSVLVFAKGDKIAEAEAAGADYVGEAEYVQKIQQGWFDFDVVVATPDMMGEVGKLGRVLGPKGLMPNPKTGTVTMDVKKAVEEIKAGKVEYRAEKAGIVHASIGKVSFTDEQLIENFNTLQDVLAKAKPSSAKGTYFKSVAVTTTMGPGVKIDTASFK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RPOB_YERPE
Sequence: MVYSYTEKKRIRKDFGKRPQVLDIPYLLSIQLDSFQKFIEQDPEGQHGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVKECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTENGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNFTTAQILDLFFEKVVFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKARRITARHIRQLEKDGIDRIEVPVEYIAGKVVAKDYVDASTGELICAANMELSLDLLAKLSQAGHKQIETLFTNDLDHGAYISETLRVDPTSDRLSALVEIYRMMRPGEPPTREAAENLFENLFFSEDRYDLSAVGRMKFNRSLLRDEIEGSGILSKEDITEVMKKLIDIRNGRGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRRVRDGVVTDEINYLSAIEEGNFVIAQANSNLDDEGRFLEDLVTCRSKGESSLFSREQVDYMDVSTQQIVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTSVAKRGGTVQYVDASRIVIKVNEDEMHPGEAGIDIYNLTKYTRSNQNTCINQMPCVNLGEPIERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLTEELQILEAGLFARIHAVLVSGGIEAEKLSKLPRERWLELGLTDEDKQNQLEQLAEQYDEMKSEFEKKMDAKRRKITQGDDLAPGVLKIVKVYLAVKRQIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGEKINAMLKKQEEVAKLREFIQKAYDLGDNVCQKVDLSTFTDDEVLRLAENLKKGMPIATPVFDGATEKEIKELLQLGGLPTSGQITLFDGRTGEQFERQVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGDHRMEPGMPESFNVLLKEIRSLGINIELEEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: YEBE_ECOLI
Sequence: MANWLNQLQSLLGQSSSSTSSSADQGLVKLLVPGALGGLAGLLVANKSARKLLTKYGTNALLVGGGAVAGTVLWNKYKDKIRAAHQDEPQFGAQSTPLDERTARLILALVFAAKSDGHIDAKERAAIDQQLRGAGVEEQGRVLIEQAIEQPLDPQRLATGVRNEEEALEIYFLSCAAIDIDHFMERSYLNALGDALKIPQDVRDGIERDLEQQKRTLAE
What are the official names of this protein?
Inner membrane protein YebE.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MND1_ARATH
Sequence: MSKKRGLSLEEKREKMLQIFYESQDFFLLKELEKMGPKKGVISQSVKDVIQSLVDDDLVAKDKIGISIYFWSLPSCAGNQLRSVRQKLESDLQGSNKRLAELVDQCEALKKGREESEERTEALTQLKDIEKKHKDLKNEMVQFADNDPATLEAKRNAIEVAHQSANRWTDNIFTLRQWCSNNFPQAKEQLEHLYTEAGITEDFDYIELSSFPLSSSHEADTAKQLVQDEA
What is the function of this protein?
Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.  Stimulates both DMC1/LIM15- and RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.
What are the official names of this protein?
Meiotic nuclear division protein 1 homolog, AtMND1, Meiotic nuclear division 1-like protein.
What is the protein family that this protein belongs to?
Belongs to the MND1 family.
Protein: 143G1_ONCMY
Sequence: MVDREQLVQKARLAEQAERYDDMAAAMKSVTELNEALSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKMEMVRAYREKIEKELETVCRDVLNLLDNFLIKNCNETQHESKVFYLKMKGDYYRYLAEVATGEKRVGVVESSEKSYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQZDDEGGETNN
What is the function of this protein?
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways.  Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif.  Binding generally results in the modulation of the activity of the binding partner (By similarity).
What are the official names of this protein?
14-3-3 protein gamma-1, Protein 14-3-3G1.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUP_SALG2
Sequence: MSTDNKQSLPSITLAAIGVVYGDIGTSPLYTLRECLSGQFGFGVERDAVFGFLSLIFWLLIFVVSIKYLTFVMRADNAGEGGILTLMSLAGRNTSARTTSMLVIMGLIGGSFFYGEVVITPAISVMSAIEGLEIVAPQLDTWIVPLSIIVLTLLFMIQKHGTGMVGKLFAPIMLTWFLILAVLGLRSIIANPEVLHALNPVWAVRFFLEYKTVSFIALGAVVLSITGVEALYADMGHFGKFPIRLAWFTVVLPSLVLNYFGQGALLLKHPEAIKNPFFLLAPDWALIPLLILAALATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMESGQIYIPFVNWLLYFAVVVVIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARKNWHWNKYFVALILIAFLCVDIPLFSANLDKLLSGGWLPLSLGLIMFTIMTTWKSERFRLLRRMHEHGNSLEAMIASLEKSPPVRVPGTAVYMSRALSVIPFALLHNLKHNKVLHERVILLTLRTEDAPYVHNVRRVQIEQLSPTFWRVVASYGWRETPNVEEVFHRCGLEGLSCRMMETSFFMSHESLIVGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI
What is the function of this protein?
Responsible for the low-affinity transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Low affinity potassium transport system protein Kup, Kup system potassium uptake protein.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPD_DESAL
Sequence: MKNLKVARRYAKALLLIGKEDGQAEVYREELEAFSSLFKANPDLEAAISNPIYEAKGRQALLRSVVEKSGVSAVTASYLLLLFDKGRIGFLDVITSEYKEMADELKGIARASVSAATELSNETIEKIRSGLGRLTGKEVVLTVSQDPALIGGIVTKIGDLVLDGSIRTQLLNLKETLKRSEAV
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL36_MARSD
Sequence: MKVRPSVKKICPKCKVIRRKGVLRVICDNPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RGP1_MOUSE
Sequence: MIEVVAELSRGPVFLAGEALECVVTVTNPLPPTATSASSEALAWASAQIHCQFHASESRVALPPPDSSQPDVQPDSQTVFLPHRGERGQCILSTPPKILFCDLRLDPGESKSYSYSEVLPTEGPPSFRGQSVKYVYKLTIGCQRVNSPITLLRVPLRVLVLTGLQDVHFPQDEAVAPSSPFLEEDDSGKKDSWLAELAGERLMAATSCRSLHLYNISDGRGKVGTFGIFKSVYRLGEDVVGTLNLGEGTVACLQFSVSLQTEERVQPEYQRRRGTGVAPSVSHVTHARHQESCLHTTRTSFSLPIPLCSTPGFCTAIVSLKWRLHFEFVTSREPGLVLLPPLEQPEPATWTGPEQVPVDTFSWDLPIKVLPTSPTLVSYAAPGPSTSSITI
What is the function of this protein?
The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP and may thereby required for efficient fusion of endosome-derived vesicles with the Golgi compartment.  The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors.
What are the official names of this protein?
RAB6A-GEF complex partner protein 2, Retrograde Golgi transport protein RGP1 homolog.
What is the protein family that this protein belongs to?
Belongs to the RGP1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane.
Protein: IPYR_RICCN
Sequence: MFIDKIKAKANNYEINVIIEIPMNSGPIKYEFDKESGAIFVDRFMQTTMSYPCNYGFIPHTLSNDGDPVDVLVVAHHPVVPGSVIKCRAVGVLMMEDESGLDEKIIAVPTSKLDITFDHIKELDDLCDMLKQRIVHFFEHYKDLEKGKWVKVTGWENKSKADALINEGIDRVS
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NVFL_ASPN1
Sequence: MDPWIALSSPLTSQTVEYVANTLRIMCAISWNISYMSMAYYSFRDKTYGNALIPLCNNIAWEFVYSFIHCPKLTFVRIENTGWFLLNIVVMYAAIKYSENEWKHAPLVQRNLPFIFAVGISAMIAGHLALAAQIGPRIAFVWSAKGCQLVLSTGALSQLLSRGSTRGGSYVVWLSRYLGTVFIDVMVTIRHVYRAAGPSWPSSPLLLWFMAVFHLLDWTYGFCFYHIRRQELVSEAAEKDKDK
What is the function of this protein?
Terpene cyclase; part of the gene cluster that mediates the biosynthesis of novofumigatonin, a heavily oxygenated meroterpenoid containing a unique orthoester moiety (PubMed:29968715).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide synthase nvfA via condensation of one acetyl-CoA starter unit with 3 malonyl-CoA units and 2 methylations (PubMed:29968715).  DMOA is then converted to farnesyl-DMOA by the farnesyltransferase nvfB (PubMed:29968715).  Epoxydation by FAD-dependent monooxygenase nvfK, followed by a protonation-initiated cyclization catalyzed by the terpene cyclase nvfL leads to the production of asnavolin H (PubMed:29968715).  The short chain dehydrogenase nvfC then as a 3-OH dehydrogenase of asnovolin H to yield chemesin D (PubMed:29968715).  There are two branches to synthesize asnovolin A from chemesin D (PubMed:29968715).  In one branch, chemesin D undergoes Baeyer-Villiger oxidation by nvfH, methylation by nvfJ, and enoyl reduction by the nvfM D enoylreductase that reduces the double bond between C-5'and C-6', to form respectively asnovolin I, asnovolin K, and asnovolin A (PubMed:29968715).  In the other branch, the methylation precedes the Baeyer-Villiger oxidation and the enoyl reduction to yield asnovolin A via the asnovolin J intermediate (PubMed:29968715).  Asnovolin A is further converted to fumigatonoid A by the Fe(II)/2-oxoglutarate-dependent dioxygenase nvfI that catalyzes an endoperoxidation reaction (PubMed:29968715).  The alpha/beta hydrolase nvfD then acts as an epimerase that converts fumigatonoid A to its C-5' epimer, which then undergoes spontaneous or nvfD-catalyzed lactonization (PubMed:29968715).  The following step utilizes the ketoreductase nvfG to produce fumigatonoid B (PubMed:29968715).  The dioxygenase nvfE further converts fumigatonoid B into fumigatonoid C (PubMed:29968715).  Finally the Fe(II)/2-oxoglutarate-dependent dioxygenase nvfF catalyzes two rounds of oxidation to transform fumigatonoid C into the end product, novofumigatonin A (PubMed:29968715).
What are the official names of this protein?
Asnovolin H synthase nvfL, Novofumigatonin biosynthesis cluster protein L, Terpene cyclase nvfL.
What is the protein family that this protein belongs to?
Belongs to the paxB family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: COAD_FRACC
Sequence: MRRAACPGSFDPITNGHLDIIVRASRLFDEVVVAVSINKNKVTLFTVDERMELIREALRDHPMAPSNVLVDASHGLIVDFCRSRGIQSIVKGLRAVSDFDYELQMAQMNNSLAGVETLFMSTNPQYAFLSSSLVKEVARYGGDVSGLVPDVVLKQLRERLAQ
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAS0_CLOPE
Sequence: MSKSLVPEAKNGLSKFKNEVARELGVPFSDYNGDLSSRQCGSVGGEMVKRMVEAYESQIK
What is the function of this protein?
SASP are bound to spore DNA.  They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation.  They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.
What are the official names of this protein?
Small, acid-soluble spore protein 1, SSP-1.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta-type SASP family.
Protein: GLPK_ECOHS
Sequence: MTEKKYIVALDQGTTSSRAVVMDHDANIISVSQREFEQIYPKPGWVEHDPMEIWATQSSTLVEVLAKADISSDQIAAIGITNQRETTIVWEKETGKPIYNAIVWQCRRTAEICEHLKRDGLEDYIRSNTGLVIDPYFSGTKVKWILDHVEGSRERARRGELLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHTLDWDDKMLEVLDIPREMLPEVRRSSEVYGQTNIGGKGGTRIPISGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNTGEKAVKSENGLLTTIACGPTGEVNYALEGAVFMAGASIQWLRDEMKLINDAYDSEYFATKVQNTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNANHIIRATLESIAYQTRDVLEAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGLAVGFWQNLDELQEKAVIEREFRPGIETTERNYRYAGWKKAVKRAMAWEEHDE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.