PharMolix/UniProtQA huggingface dataset:
Protein: UPPP_STAAE
Sequence: MFIIELIKGIILGVVEGLTEFAPVSSTGHMILVDDMWLKSSEFLGSQSAFTFKIVIQLGSVFAAAWVFRERFLEILHIGKHKHVEGDNDQQRRSKPRRLNLLHVLVGMVPAGILGLLFDDFIEEHLFSVPTVMIGLFVGAIYMIIADKYSAKVKNPQTVDQISYFQAFVIGISQAVAMWPGFSRSGSTISTGVLMKLNHKAASDFTFIMAVPIMLAASGLSLLKHYQDIQIADIPFYILGFLAAFTVGLIAIKTFLHLINKIKLIPFAIYRIVLVIFIAILYFGFGIGKGI
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YAEP_ECODH
Sequence: MEKYCELIRKRYAEIASGDLGYVPDALGCVLKVLNEMAADDALSEAVREKAAYAAANLLVSDYVNE
What are the official names of this protein?
UPF0253 protein YaeP.
What is the protein family that this protein belongs to?
Belongs to the UPF0253 family.
Protein: MRAY_BURM9
Sequence: MLLALAQWLQGDASFLRLFTYLTFRAVMATITALVIGLVCGPWVIRKLTQMKVGQAVRKDGPQTHLVKSGTPTMGGVLILIGIAVATLLWGDLTNRFIWIVMLVTFGFGVIGWVDDYRKVVYKDPRGMSSREKYFWQSVIGLFAAVYLAFSVSEANNVRVFDLFMAWVRSGLSMGLPARADLMLPFLKSISYPLGVWGFIALTYFVIVGASNAVNLTDGLDGLVIMPVVLVGASLGVFAYVMGSAVYSKYLLFPHIPGAGELLIFCSAMGGAGLAFLWYNTHPAQVFMGDVGALALGGALGTVAVIVRQEIVLFIMGGIFVAETLSVMLQVTWFKYTKKRYGEGRRIFKMAPLHHHFELSGWKETQVVVRFWIITLMLCLFGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NEOD_STRFR
Sequence: MRVLRLTPFFHHDCVTAWPAEFDAVGGMQVQILRLSRELADRGVEQLVMTVGFPGLPRERVDRPGLRVRVTRAPLPRLRSELTGLVGLNQAWLAAVLTACAPLRRTWRPDLVHVHADGQLWALLAGPLVSRLVGAPYCLTLHCSRLASYEPMSRFDRLQHRLVAAAERYALRRARRVSTLTSRTADTVARLLPLDRALVDVLPDSVGDVRPVARPEAEEYVRSLGVPAGRPVVGWVGRVAHEKGWRDFVAMAERWDAGSGAPGAVFAVVGDGPQRERMREAVEAAGLADRFVFTGFLPHDAVPSVMTALDVLVMPSAHEELGGSALEAMVCGTPVAGYAVGGLRDTVGSVTPSLLVPRGDVAALTRAAGDAVTDAERHRKTVAAAVPDLLGRYGADTVERALEHYRLAVGRASGGGAGWAP
What is the function of this protein?
Glycosyltransferase involved in the biosynthesis of neomycin by mediating conversion of 2-deoxystreptamine (2-DOS) to 2'-N-acetylparomamine using UDP-alpha-D-glucosamine as sugar donor.
What are the official names of this protein?
2-deoxystreptamine N-acetyl-D-glucosaminyltransferase, Neomycin biosynthesis protein 8, Neo-8, Neomycin biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
Protein: SACA_NEIMA
Sequence: MKVLTVFGTRPEAIKMAPVILELQKHNTITSKVCITAQHREMLDQVLSLFEIKADYDLNIMKPNQSLQEITTNIISSLTDVLEDFKPDCVLVHGDTTTTFAASLAAFYQKIPVGHIEAGLRTYNLYSPWPEEANRRLTSVLSQWHFAPTEDSKNNLLSESIPSDKVIVTGNTVIDALMVSLEKLKITTIKKQMEQAFPFIQDNSKVILITAHRRENHGEGIKNIGLSILELAKKYPTFSFVIPLHLNPNVRKPIQDLLSSVHNVHLIEPQEYLPFVYLMSKSHIILSDSGGIQEEAPSLGKPVLVLRDTTERPEAVAAGTVKLVGSETQNIIESFTQLIEYPEYYEKMANIENPYGIGNASKIIVETLLKNR
What is the function of this protein?
Catalyzes the interconversion between UDP-N-acetylglucosamine (UDP-GlcNAc) and UDP-N-acetylmannosamine (UDP-ManNAc).  Involved in the biosynthesis of the capsular polysaccharides.  In vitro, can also use several chemoenzymatically synthesized UDP-ManNAc derivatives as substrates, with lower efficiency.
What are the official names of this protein?
UDP-N-acetylglucosamine 2-epimerase, UDP-GlcNAc 2-epimerase.
What is the protein family that this protein belongs to?
Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
Protein: CH602_MYCSJ
Sequence: MAKTIAYDEEARRGLERGLNALADAVKVTLGPKGRNVVLEKKWGAPTITNDGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLRNVAAGANPLGLKRGIEKAVEKVTETLLKSAKEVETKEQIAATAGISAGDQSIGDLIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYISGYFVTDAERQEAVLEDPYILLVSSKISTVKDLLPLLEKVIQSGKPLLIIAEDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGGQVISEEVGLSLETADISLLGQARKVVITKDETTIVEGAGDAEAIQGRVAQIRAEIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRNAKAAVEEGIVAGGGVALLQAAPSLEELNLTGDEATGANIVRVALEAPLKQIAFNGGLEPGVVAEKVRNSAAGTGLNAATGEYEDLLAAGVADPVKVTRSALQNAASIAALFLTTEAVVADKPEKSAAPAGDPTGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Secreted, capsule. Cell surface. Secreted, cell wall.
Protein: RIR1_EBVA8
Sequence: MATTSHVEHELLSKLIDELKVKANSDPEADVLAGRLLHRLKAESVTHTVAEYLEVFSDKFYDEEFFQMHRDELETRVSAFAQSPAYERIVSSGYLSALRYYDTYLYVGRSGKQESVQHFYMRLAGFCASTTCLYAGLRAALQRARPEIESDMEVFDYYFEHLTSQTVCCSTPFMRFAGVENSTLASCILTTPDLSSEWDVTQALYRHLGRYLFQRAGVGVGVTGAGQDGKHISLLMRMINSHVEYHNYGCKRPVSVAAYMEPWHSQIFKFLETKLPENHERCPGIFTGLFVPELFFKLFRDTPWSDWYLFDPKDAGDLERLYGEEFEREYYRLVTAGKFCGRVSIKSLMFSIVNCAVKAGSPFILLKEACNAHFWRDLQGEAMNAANLCAEVLQPSRKSVATCNLANICLPRCLVNAPLAVRAQRADTQGDELLLALPRLSVTLPGEGAVGDGFSLARLRDATQCATFVVACSILQGSPTYDSRDMASMGLGVQGLADVFADLGWQYTDPPSRSLNKEIFEHMYFTALCTSSLIGLHTRKIFPGFKQSKYAGGWFHWHDWAGTDLSIPREIWSRLSERIVRDGLFNSQFIALMPTSGCAQVTGCSDAFYPFYANASTKVTNKEEALRPNRSFWRHVRLDDREALNLVGGRVSCLPEALRQRYLRFQTAFDYNQEDLIQMSRDRAPFVDQSQSHSLFLREEDAARASTLANLLVRSYELGLKTIMYYCRIEKAADLGVMECKASAALSVPREEQNERSPAEQMPPRPMEPAQVAGPVDIMSKGPGEGPGGWCVPGGLEVCYKYRQLFSEDDLLETDGFTERACESCQ
What is the function of this protein?
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis.  Allows virus growth in non-dividing cells, as well as reactivation from latency in infected hosts.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase large subunit, R1, Ribonucleotide reductase large subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase large chain family.
Protein: LSPA_FUSNN
Sequence: MSKMCSSVEIGDSMIYIFLFLILLIIDQYSKFIVDSTLSVGETVPVIDGFFNLTYVQNRGVAFGLFQGKIDIVSILAVIAIGLILFYFCKNFKKISFLERIAYTMIFSGAIGNMIDRLFRAYVVDMLDFRGIWSFIFNFADVWINIGVVLIIVEHIFFNRKKRVK
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL3_YERPE
Sequence: MIGLVGKKVGMTRIFTEDGVSIPVTVIEIEANRVTQVKSLENDGYRAVQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLPEGQEFTAGQEISVEIFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGHMGDERVTVQSLDVVRVDAERNLLLVKGAVPGATGGNLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: SHLB2_MOUSE
Sequence: MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTERILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMAEAASELGPSTPYGKTLIKVSEAEKRLGAAERDFIHTASLSFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTTAATMPVVPTGAVLAPPEEAALCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS
What are the official names of this protein?
Endophilin-B2, SH3 domain-containing GRB2-like protein B2.
What is the protein family that this protein belongs to?
Belongs to the endophilin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SASA_NOSP7
Sequence: MLKHDYMQVSQDQPIYSEAPLQLLLFVDGRPKSRQQVQRIRAYLKELQAEYTFEVQTIDVGQQPYLAEHFKLVATPALIKIHPEPRQVLAGSNIIAQLKNWWPRWQVAVDAYLKLQEDLQEHMDDNGRGTLPKSTIHSVAVSAELIRLSDEIFRLKQEKDNLQEQLQFKDRVIAMLAHDLRNPLTAAAIAIETLQSNYNLETGEFQRLKPSMTAHLLKQARNQTKVIDRMITDLLQVGRGKDTEFPLSPQKVQLGKVFLDVLEELCDRYTAKSQEVETDIPSDLPYVYADPERIRQVLVNLLDNAIKYTPEGGKISVSGLHRTTQKVQFSIGDTGPGIPVENRDRIFENHFRLQRDEGKEGYGIGLCLCQRIIVAHYGQIWVDSAPNNGAWFHFTLPVYPS
What is the function of this protein?
Member of the two-component regulatory system SasA/RpaA involved in genome-wide circadian gene expression.  One of several clock output pathways.  Participates in the Kai clock protein complex, the main circadian regulator in cyanobacteria, via its interaction with KaiC.  KaiC enhances the autophosphorylation activity of SasA, which then transfers its phosphate group to RpaA to activate it.  In addition to its output function, recruits fold-shifted KaiB (KaiB(fs)) to KaiC to cooperatively form the KaiB(6):KaiC(6) complex (independent of SasA kinase activity).  Required for robustness of the circadian rhythm of gene expression and is involved in clock output, also required for adaptation to light/dark cycles.
What are the official names of this protein?
Adaptive-response sensory kinase SasA, Sensor histidine kinase SasA.
Protein: LPXD1_KORVE
Sequence: MKLSEIARRLGCTLDNCPDPDAVEITAVTGIEAAGPTDITFVSNPRYAAAAKTTHAGAIIVSDDFTAGRAPLVRSKNPYLTFAKAIELFYQAPKYAPGIHPTAVISPTAKVGANASIGPYVVIEDNVAIGANCVLRAHVVIYEGVTIGDNFFAHAHAVVREHCRIGNNVILQNGVVIGADGYGFARDTDGWYKIAQSGTTILDDNVEVQANSTVDRASIGETHIYADAKIDNLVMIGHGSSVGEHSLLCSQVGLAGSSHVGKNVILAGQVGVAGHLHIGDGVIAAGQTGVQNDIEPGKRIGGSPSYDHKQWIRSWQIQTRLPEIVKELRNLASKKSE
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: VF62_ASFK5
Sequence: MRNTPFVVKINIIFLKVVSNTAVSVFCRDRRIRFNSDWSNSYFQK
What are the official names of this protein?
Uncharacterized protein C62L, pC62L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus C62L family.
Protein: RS11_MESFL
Sequence: MAKPKTNNTKKRIKKNIPKGIAHIHSTFNNTIVTISDEKGNVLSWSSAGAIGFKGSKKSTPYAAQMISEAAAKGAMDQGVKSVQVEVKGPGPGRDAAVRALTIVGMEVTSIKDCTPIPHNGVRPKKRPRK
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: TM215_BOVIN
Sequence: MRPDDINPRTGLVVALVSVFLVFGFMFTVSGMKGETLGNIPLLAIGPAICLPGIAAIALARKTEGCTKWPENELLWVRKLPCFRKPKDKEVVELLRTPSDLESGKGSSDELAKKAGLRGKPSLQGQGELPMASSITTPTPMEEGECQSPGQSGRREETSRYLDGYCPSGSSLTYSALDAKCSAWDRSEHPEPEDSIFFVPQDSIIVCSYKQNSPYDRYCCYINQSQGRWDHETIV
What are the official names of this protein?
Transmembrane protein 215.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MIAA_ACAM1
Sequence: MTPGLIVICGPTATGKSSLALALARRLGAPILSADSRQVYRGFDIGTAKPSVTDQEDVPHYLIDICDPTETLTVADYQEQAQALIAQFHTEGQTPILVGGTGLYIRAIVEGLKIPRVPPQLELRSQLQSQGQVQIYQWLQQVDPPAAQKIHAHDQVRTLRALEVFYTTGIPLSAQQGKNPPSYPILQIGLDISDLDQHTDIIQQRTAAMVEQGWLTEVQKLIDHYGVELPLLATLGYQEMKAYLHQQITLEEATAQTILHTRQFAKRQRTWFRANSGIHWFDATNSDLLSLVWKDIQGQPWL
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: ILVE_STAAR
Sequence: MSQAVKIELRETLKEKPDTSQLGFGKYFTDYMLSYDYDADKGWHDLKIVPYGPIEISPAAQGVHYGQSVFEGLKAYKKDGEVALFRPDENFKRLNNSLARLEMPQVNEGELLEGLKQLVDLEREWVPEGEGQSLYIRPFVFATEGVLGVGASHQYKLLIILSPSGAYYGGETLKPTKIYVEDEYVRAVRGGVGFAKVAGNYAASLLAQTNANKLGYDQVLWLDGVEQKYIEEVGSMNIFFVENGKVITPELNGSILPGITRKSIIELAKNLGYEVEERRVSIDELFESYDKGELTEVFGSGTAAVISPVGTLRYEDREIVINNNETGEITQKLYDVYTGIQNGTLEDKNGWRVVVPKY
What is the function of this protein?
Acts on leucine, isoleucine and valine.
What are the official names of this protein?
Probable branched-chain-amino-acid aminotransferase, BCAT.
What is the protein family that this protein belongs to?
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
Protein: RS8_KLEP3
Sequence: MSMQDPIADMLTRIRNGQAANKAAVTMPSSKLKVAIANVLKEEGFIEDFKVEGDIKPELELTLKYFQGKAVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVVSTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: GATC_LEPBJ
Sequence: MNLNEDSLRKIAELSRLNIRPKEKEATLRDFNKILEYVDQVKGLDVSSIRDDEIYFRHENSIRPDLVGQHLSREEIEKFAPSFQNGYFVVPKVIET
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: RNZ_SALAI
Sequence: MSTRELVVLGTASQAPTRTRNHNGYVLRWDDEVILFDPGEGSQRQLLYSSVTATDLTRICVTHFHGDHCLGLPGTIQRLSLDRVPHPVAVHFPAGGADYFTRLRYASSFHETAELAVMPIDTDGQQIAVRNGTLEARRLRHPIETYGYRLVEPDGCRMLPERLSAHGIAGPAVGELLRVGHLDVNGRRVTRAEVSAPRPGQRFAFVMDTGLCDAVYALAEHADLLVIESTFLASETALAAEVGHLTAAQAARVATESGVRRLVLTHFSQRYPDLSRFAAEAREHFTGDLVIAEELMTVGIPPRRVPSAG
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: DKK4_MOUSE
Sequence: MVLVTLLGLSWFCSPLAALVLDFNNIKSSADVQGAGKGSLCASDRDCSEGKFCLAFHDERSFCATCRRVRRRCQRSAVCCPGTVCVNDVCTAVEDTRPVMDRNTDGQDGAYAEGTTKWPAEENRPQGKPSTKKSQSSKGQEGESCLRTSDCGPGLCCARHFWTKICKPVLREGQVCSRRGHKDTAQAPEIFQRCDCGPGLTCRSQVTSNRQHSRLRVCQRI
What is the function of this protein?
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6.  DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation.  In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
What are the official names of this protein?
Dickkopf-related protein 4, Dickkopf-4, Dkk-4.
What is the protein family that this protein belongs to?
Belongs to the dickkopf family.
What are the subcellular locations of this protein?
Secreted.
Protein: UFC1_HUMAN
Sequence: MADEATRRVVSEIPVLKTNAGPRDRELWVQRLKEEYQSLIRYVENNKNADNDWFRLESNKEGTRWFGKCWYIHDLLKYEFDIEFDIPITYPTTAPEIAVPELDGKTAKMYRGGKICLTDHFKPLWARNVPKFGLAHLMALGLGPWLAVEIPDLIQKGVIQHKEKCNQ
What is the function of this protein?
E1-like enzyme which specifically catalyzes the second step in ufmylation (PubMed:15071506, PubMed:29868776).  Accepts the ubiquitin-like modifier UFM1 from the E1 enzyme UBA5 and forms an intermediate with UFM1 via a thioester linkage (PubMed:15071506, PubMed:29868776).  Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress (PubMed:32160526).
What are the official names of this protein?
Ubiquitin-fold modifier-conjugating enzyme 1, Ufm1-conjugating enzyme 1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
Protein: S2538_MAGO7
Sequence: MSDGTSKSGSKSSFHFVAGLGSGVLSAALLQPIDLLKTRVQQSPHQNILRTVSEIRHTSPAGLRGLWRGTVPSALRTGFGSALYFSTLNAIRQAAVPLFAHDAAVTTSPNGGNFANNKNNSSRLVKLSNTGNLLAGGVARGFAGFVLMPLTVIKVRYESSLYSYRSIAGAAGDILRTEGPRGFFAGFGATALRDAPYAGLYVLLYEQFKRRLGGVVSSSAAPETNEDNRMGVSRAAAVNFSSGVLAAVACSVVSNPFDAVKTRIQLRPGRYRNMVVAARTMMAEEGARSFFSGLGLRMSRKALSSALAWTLYEELIMRAEVGWSLSSSRTERAM
What is the function of this protein?
Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix.  Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix.
What are the official names of this protein?
Mitochondrial glycine transporter, Solute carrier family 25 member 38 homolog.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RE114_SACPA
Sequence: MYEYCSVVIKKYSKYTIPSFAPNGFCSMLEPPQIDKWQHLSTNCTLQFRVLLMDSGQVLIHVVLNNSTLLENIRLPLGDNQDLIQFSCKCPIISCKYISEEFGPRMLRRFQINLPNDIEFNRAIVSLKNLNFVLRTAKTSIAQNTITSQVLDINNGKKVNFAEGTNTSNYAHSNTQFQTQNMITDFSQRCQEKSEREPSNRSNITLPQDNFPIGQQSWPNTELNVVHSSQDLNTPSATQTVLSRPEPLNVQPSEVSQSLAKTTSCLPNIGNQKNQTETISDLLSRKDIAPCKPGLMEVVHLPKERVEKESRMHSTTGLVKTPTTTVWSLEKENTIRQNSNNKENADNKLSDSQKSRGINTPNRRTEIPLNGTLNGTKEEVSLGGEITVSVKNANRNASRKISKRLIKEKLKDKEFMNWVNKVETVLNKMFEK
What is the function of this protein?
Required for meiotic recombination events; not required for mitosis.
What are the official names of this protein?
Meiotic recombination protein REC114.
What is the protein family that this protein belongs to?
Belongs to the REC114 family.
Protein: TRUA_PROM4
Sequence: METEASNESIEKSLPKRIALLIQYNGSGFCGWQRQKEGNSVQSILEEAVSSLDPFQPIKVVAAGRTDSGVHASGQVAHFDCSGFIPANRWAAALNGRLPKAIRVRYSALRPITWHACFSATYRRYRYTIYNGCKPNLFLSPWCWHRYQFRLDENLMNLALQGIKGFHDFTAFQRAGSNRPNALTTVEDVHLFRQGDLVSIDIQATGFLYGMVRLLVGQLVAVGEHRISVAEFERRWKLKLREEVREAAPPNGLSLIRVGYETMIFPENIAFDSFPFFSLSTSDPPPSPQ
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: Y2618_GEOKA
Sequence: MAWMIRDVPKDSRPRERLLSSGPESLSDHELIAILLRTGTKEESVVQLAQRLLRHFEGLRPLKDATVEEMTNIKGIGPTKAVQILAALELGRRIHQSGCADRYVIRCPEDGAKYVMEDMRFLSQEHFVAIYLNTKNQVIYRKTVFIGSLNASIVHPREVFKEAIKRSAASVICVHNHPSGDPTPSREDIDVTKRLAECGRIIGIELLDHLIIGDQKFISLKEKGYV
What are the official names of this protein?
UPF0758 protein GK2618.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: EX7L_STRT2
Sequence: MSDYLSVTSLTKYLKMKFDRDPYLERVYLTGQVSNYRRRPSHQYFSLKDEGAVIQATIWAGVFKKIGFDLEEGMKINVVGRVQIYEPSGSYSLIIEKAEPDGIGALALQFEQLRKKLTAEGYFDDRHKQPLPNFVKKIGVITSPSGAVIRDIITTVSRRFPGVEILLFPTKVQGDGAAQEIVENIQKANQREDLDLLIVGRGGGSIEDLWAFNEEIVVQSIFESRLPVISSVGHETDTTLADFVADRRAATPTAAAELATPISKADTLAWIRERQNRAYQACLRRIQYNQERLAKLSQSVVFRQPERLYDGYLQKLDRLTTRLETFMSQDFERKQKSAEFLRQRLHGLNLSTRVKNYQDRRESLQRLLVTTTKNTINGNRVRLEKAQDALLSLDTSRIVARGYAIVNKNDKPLTTIKDITEGEQLTIQMRDGQLEVEVKNVNEKNI
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_METM5
Sequence: MNKPVLVSFLVSGDPNPDATLKFMKTLDKYSGVIELGIPFSDPVADGPTIQAADVRALSNGFKIAKSFEVLKEFRKESDTPVILMTYYNPVFKRGIENFVISAKEAGAKGLIIVDLPLQEATEYREICKKHEMGTVFLAAPNTPEERLKISDEASTEFLYLISTFGITGARDTFEQMTFDFIKRARTTCKGKICVGFGISKGSHAESLIEQGADGVIVGSAFVDIIKNYGDSEEALVKLEEFAKELSEGIDKGYEKRNK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RL22_SALPC
Sequence: METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: YDJN_BACSU
Sequence: MKKRIILLLAVIIAAAAAGVAFYVAKDKGHEKAADVSVNTESGDELLVSITDTDLLTKYYENDKVIHEEKLTSYPAFALDQKQQVLYYTGNNEQNEMRLFKLDLKSHKKTMLYKGAESADSLFLSKDRSTIYFRLGKADESNFRIAAFDLKTKKYKNLYPAANDQDDTVSSFFYNQKNDSFALLHYSVEEDYKKTDEANEKGIDPEPTTIHFAEGRQNKFNELKSLNQFISDIAVSDDDKRILFTSYTQKGTEQTASIQMLNADTKKYESIISNQKSFKLLIDAQPQFSKDGKNIYFLAEAKGAKKLKDETGREAKVRTIYSYSLENKTFKKVWENPNGIINSFFVIN
What are the official names of this protein?
Uncharacterized protein YdjN.
Protein: RIHB_ECO7I
Sequence: MEKRKIILDCDPGHDDAIAMMMAAKHPAIDLLGITIVAGNQTLDKTLINGLNVCQKLEINVPVYAGMPQPIMRQQIVADNIHGETGLDGPVFEPLTRQAESTHAVKYIIDTLMASDGDITLVPVGPLSNIAVAMRMQPAILPKIREIVLMGGAYGTGNFTPSAEFNIFADPEAARVVFTSGVPLVMMGLDLTNQTVCTPDVIARMERAGGPAGELFSDIMNFTLKTQFENYGLAGGPVHDATCIGYLINPDGIKTQEMYVEVDVNSGPCYGRTVCDELGVLGKPANTKVGITIDTDWFWGLVEECVRGYIKTH
What is the function of this protein?
Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.  Has a clear preference for cytidine over uridine.  Strictly specific for ribonucleosides.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihB, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihB subfamily.