PharMolix/UniProtQA huggingface dataset:
Protein: Y901_BACAN
Sequence: MKVSKVYTTIDAHVAGEPLRIITGGVPEIKGETQLERRWYCMEHLDYLREVLMYEPRGHHGMYGCIITPPASAHADFGVLFMHNEGWSTMCGHGIIAVITVGIETGMFETKQKFIIDSPAGEVIAYAKYNGSEVESVSFENVPSFVYKKDVPIKIDNYEFQVDIAFGGAFYAVVDSKEFGLKVDFKDLSAIQQWGGKIKHYIESKMEVKHPLEEGLKGIYGVIFSDDPKGEGATLRNVTIFADGQVDRSPCGTGTSARIATLFEKGILQKGEIFIHECITDGEFEGEVLSVTAVHTYEAVVPKVTGNAFITGFHQFVVDPRDDLNRGFLLG
What are the official names of this protein?
Uncharacterized protein BA_0901/GBAA_0901/BAS0853.
What is the protein family that this protein belongs to?
Belongs to the proline racemase family.
Protein: HISZ_HELHP
Sequence: MILEHELPQGSKLYFDMSARLKRDIESCAIKAFYENDYREIVTPSFAFLEHQGDMFNREIVRLSSENNHQIGLRYDTTLDAMRIVTKRIMRSSTHKKWFYIQPVFSYPTTEIHQIGAEYLGGESLSPVMCLGVSILQTLNLAPYLQISNMKIPFLCAKHSDVDIEVFALQNVGKLLQMEGYMADLVHIKTKQDLQKAILSAPAFLKEELERLLECASYCEYEKTIFSPLLFAPSPYYEDLFFRMFVGNSTLLQGGKYSVEEQFSCGFAIYTDEVVECLLS
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFW_AZOBR
Sequence: MSFKDDLEDLETAEDFLRFLGVTYEQRVVNVNRLHILQRFQDYLSADTGMEGLDDEGMAARYSAHLERAYQDFVASNAIAEKTFKVHQEEARKMADRFVPLDALLPT
What is the function of this protein?
May protect the nitrogenase Fe-Mo protein from oxidative damage.
What are the official names of this protein?
Nitrogenase-stabilizing/protective protein NifW.
What is the protein family that this protein belongs to?
Belongs to the NifW family.
Protein: CNDC1_RHIWD
Sequence: MAQYDVLIVGAGHGGAQAAVALRQNKFEGTIAIVGDEPELPYERPPLSKEYFSGEKSFDRILIRPATFWAERNVDMLLGKRVASVDPAGHSVTLTDGSTIGYGKLVWATGGAPRKLACSGHHLSGVHGVRTREDADRMLGEMERTTSVVVIGGGYIGLEAAAVLSKAGKKVTVLEALDRVLARVAGEALSRFYEAEHRAHGVDVQLGAKVDCIVGDDQDRVTGVQMHDGSVIPADMVIVGIGIIPAVEPLIAAGAAGGNGVDVDEYCRTSLPDIYAIGDCAMHANAFAEGARIRLESVQNANDQATTAAKHILGGTDAYHAVPWFWSNQYDLRLQTMGLSIGYDETIVRGDPANRSFSVVYLKNGRVLALDCVNAVKDYVQGKALVTGGVSPDKASLANPEIPLKTLLPA
What is the function of this protein?
Component of the chloroacetanilide N-alkylformylase multicomponent enzyme system involved in the degradation of chloroacetanilide herbicides (N-alkoxyalkyl-N-chloroacetyl-substituted aniline derivatives).  In vitro, catalyzes the transfers of electrons from ferredoxin (CndB1) to NADH.  N-dealkylase utilizes NADH, but not NADPH, as the electron donor.
What are the official names of this protein?
Chloroacetanilide N-alkylformylase, ferredoxin reductase component, Ferredoxin--NAD(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
Protein: PA2_PSEPP
Sequence: NLIQFSNMIQLDRCCETHDNEAEKKGCYPKLTLY
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that strongly inhibits platelet aggregation and has a strong anticoagulant activity.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Phospholipase A2, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CCNA2_MOUSE
Sequence: MPGTSRHSGRDAGSALLSLHQEDQENVNPEKLAPAQQPRAQAVLKAGNVRGPAPQQKLKTRRVAPLKDLPINDEHVTAGPSWKAVSKQPAFTIHVDEAEETQKRPAELKETECEDALAFNAAVSLPGARKPLTPLDYPMDGSFESPHAMDMSIVLEDKPVNVNEVPDYQEDIHTYLREMEVKCKPKVGYMKRQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYSKKQVLRMEHLVLKVLAFDLAAPTVNQFLTQYFLHLQPANCKVESLAMFLGELSLIDADPYLKYLPSLIAGAAFHLALYTVTGQSWPESLAQQTGYTLESLKPCLVDLHQTYLKAPQHAQQSIREKYKHSKYHSVSLLNPPETLSV
What is the function of this protein?
Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle.  Functions through the formation of specific serine/threonine kinase holoenzyme complexes with the cyclin-dependent protein kinases CDK1 and CDK2.  The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle.
What are the official names of this protein?
Cyclin-A2, Cyclin-A.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Exclusively nuclear during interphase. Detected in the nucleus and the cytoplasm at prophase. Cytoplasmic when associated with SCAPER.
Protein: KLF14_GORGO
Sequence: MSAAVACLDYFAAECLVSMSAGAVVHRRPPDPEGAGGAAGSEVGAAPPESALPGPGPPGPASVPPLPQVPAPSPGAGGAAPHLLAASVWADLRGSSGEGSWENSGEAPRASSGFSDPIPCSVQTPCSELAPASGAAAVCAPESSSDAPAVPSAPAAPGAPAASGGFSGGALGAGPAPAADQVPRRRPVTPAAKRHQCPFPGCTKAYYKSSHLKSHQRTHTGERPFSCDWLDCDKKFTRSDELARHYRTHTGEKRFSCPLCPKQFSRSDHLTKHARRHPTYHPDMIEYRGRRRTPRIDPPLTSEVESSASGSGPGPAPSFTTCL
What are the official names of this protein?
Krueppel-like factor 14.
What is the protein family that this protein belongs to?
Belongs to the Sp1 C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YQGF_PROMH
Sequence: MSNRTVMGFDFGTKSIGAAIGQEVTGTARPLASFKAKDGIPDWSQIEKIIKEWQPDLVVVGLPLNMDGTEQLVTTQAKKFANRLHGRFGVQIALHDERLSTVEARAHLFEQGGYRSLDKGSVDATSAVIILESWFERQY
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIV_ANTMA
Sequence: MEILAPSSYFSSSSWFLEESRSTTRWTAAENKAFENALAVFDENTPNRWERVAERVPGKTVGDVMRQYKELEDDVSSIEAGFVPVPGYSTSSPFTLEWGSGHGFDGFKQSYGTGGRKSSSGRPSEQERKKGVPWTEEEHKLFLMGLKKYGKGDWRNISRNFVITRTPTQVASHAQKYFIRQLSGGKDKRRASIHDITTVNLSDNQTPSPDNKKPPSSPDHSMAQQQTSSTSIHKLPFQWDQTSNETIMGFASSGHHGNMFQSNPFGMNSYGFKMQGQQMQRGGFCDTYLGSQNMAFQMQSGLHFPNA
What is the function of this protein?
Involved in the dorsovental asymmetry of flowers.  Promotes ventral identity.
What are the official names of this protein?
Transcription factor DIVARICATA.
What are the subcellular locations of this protein?
Nucleus.
Protein: COAD_VIBPA
Sequence: MNRSVHPMKVIYPGTFDPVTNGHLNLIERTHEMFDEVVIGVAASPSKNTMFTLEERVALMEEVVAHLPGVTVKGFSGLLVDFARQEQAKVLIRGLRTTVDFEYEFGLTNMYRKLLPGIESVFLTPEEEFAFLSSTIVREVAIHGGSIEQFVPAAVANAIEKKVNERQ
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1418_HAEIN
Sequence: MGKLSILSKRKYTMKNQIQFSTFNFKDLPVRVILDPKGEFWFCGTDVCHILGYTNSRKALQDHCKQGGVTKRYTPTKSADQEMTFINEPNLYRLIIKSRKPEAEPFEAWVFEEVLPQIRKTGKYQLQPQQLALPEPEKKFSFEFTEYELQQLVWLWFAFMRGIVTFQHIEKAFKALGSNMSGDIYGQAYEYLSVYAQQTKS
What are the official names of this protein?
Uncharacterized protein HI_1418.
Protein: ZN318_MOUSE
Sequence: MYRSGSRSSVSSHRSKDGSASGPPPGRPVGASSGPTRRPSSPPPPSCSSLRLPARRHRSPSGHRGRWASPSPPRGRRGSPSPPRGRRASPSPTRGRRASPSPPRGRRGSPSPPRARRGSPSPPRSRRHYPPGLGGFRGSIRGESRADFARDGRGDHPGGGGGSRRRSPGLCSDSSLEESLRITVGNDHFCVSTPERRRLSDRLGSPVDGLQDMDRDDLTDDSVFTRSSQCSRGLERYISREEGPLSPFLGQLDEDYRTRETFLHRPEFSPQSSCHDELLRGTERNRDKLKSSSYSIRSEERSREAKRPRYDDTEKVHSSGGDHSSFTSGTRNYRQRRSSPSPRFLDPEFRELDLARRKREEEEEQSRSLSQELVGVGDDQIGCSIPGLAGVLTTSEPGYSLQRPEEVPMMPKKSILKKRIEADMKPSLQLESFSSGASSGEDHPLYSEHSPLPLSGAIAAFTSEIENKGTTVEADLKEPQSNLYQWGPLREIPKDNSEKFDSFLGFKEKLDLKAEGLEQQTDFLLPHERASQDGSGFSRILSMLADPTITQEKRRRSFPDIEDEEKFLYGDEEEDIKSESPLKSLEDPESAGTRQKANSLPSTPAVKLESLEESNPEYAKIHNLLKTIGLDIGVAEIGKLAARTQERLHGKKPSSRPSADRRLSADRHLSGDRHFSADRCSSVEHSFTADWRSSDPHRPESRETHHSNTQSPEVSHPHPASPVDPYLRTKNSPPFLKSDHPVCHVSGPEVVGSGFQSSVAVRCMLPSAPSTPIRLPHSAALSQFHIPGASQFAAARIPPNYQGSVIPSASFDAYRHYMAYAASRWPMYPASQPPSHPLSDPHRLLPVTKQAARSRPNLRVIPTVTPAKPKQEIPVLGSISVKRIPVRVSIPSLIKYNPKKISDEKNRASQKQKVIEEREKLKTEQEARQKKMFYLTTELERLHKQQGEMLRKKRREKDGHKDPLLMEVSRLQDSIMKDIAELHKETEEAEKKQSELDKVAQILGIDIFDKSLKSSNDSKESTEKPEKEKSKSPEKELSPSNSSSSNKESKMNEKSCIKSPSSTESLQPTVKQSDQPVAAYEYYDAGSHWCKDCNTTCGTMFDFFTHMHNKKHTQTLDPYNRPWASKTQSEAKQDTVKRTDKITVPAKGSEFLIPVTGFYCQLCEEFLGDPISGEQHVKGHQHNENYKKYVEENPLYEERRNLDRQAGLAVVLETERRRQNELKRKLNEKPKEEKIEKKARIVREVKEDDKAPGELEEQLSEDGSAPEKGEVKGNASLRPQVKEEVKKEPSVASIAASFGKFSWKKPEKEEEKGSVVTPGAPKEDTVETSKDRDDGKAEVGKAKPIKIKLSGKTVIAHTSPWTPVVTTSTQTKIRPNLPIPSTVLRKSGSATVSKPAPLNTFLSIKSSGTSTKPLPVVKESSSDLLLPPDIISKAFGGEEVVLKGSPEEKVELAEKNEPSQVPEQMLALLPPPPPPPPPPPPPPPPPPPQAVPQLSAPSPAQANVVLTPVKSNSVISQTFSLGFQGPNILNPGLPVAFMASEQPTVIPSDETAPGVSESDWDQTLISMLVRPPPPLSSVFSEQAKKLEKRNSCLATANAKDLYDIFYSSGGKGAHETKLSSSTLANGESSSLPRTESSDFSSTCTLNSSMSSEDLPQCSALVTATEISNLENPISKGMESTGKWSVVDQIDPKSRDSTYSFLQPLTRLYQNKPYEIVSPKTDTLVMWTSGSSQNDTHKDRPPEGKIRFDLGEPGPPGTDSTSHLSDTHCQTNGPQKLIEINLIDNQNKNQEVYQSEGCRESEMKRKTELKGKVATEEEEEEEEEGANSIEDSNSNHGNRNTWEGEIGQPKLSTVDKKGEQSSKLMTGHENTSKVVIELSPSLPSKRTKIDLFPSLLQNPKSMPELLLLSPAGSGLCLKRQEIWERPEKPGLEDVELQGTRPELTVTIESKVLENFDTTHLEVEGFASLRNLGDMHANFHNSQTEQTRRSPTALSEKMSEEISVSSVMCNPSSSSDIEPVPSFSGFPLESPKTLVLNFETEGAHSSSNSRNGRITSNSLETGHPVENVGHDLGGERTHQALDLLAGGMLSEDVKETSPLQKDLLRMESTTVSPSGLGPSPCLPDLVDFVTRTPGVPKQKPCSPLSEPDAFLKCSSLEMGSPPPEILSVSVSEVAVPQVSEDNDSALNLVKTPPSGSPSRDQVVGGNVSPREMPEQEAAVDVIPDHTRSNVYNSQDYLNG
What is the function of this protein?
Acts as a transcriptional coactivator for AR-mediated transactivation function.  May act as a transcriptional regulator during spermatogenesis and in particular, during meiotic division.
What are the official names of this protein?
Zinc finger protein 318, Testicular zinc finger protein.
What are the subcellular locations of this protein?
[Isoform 1]: Nucleus. SUBCELLULAR LOCATION: [Isoform 2]: Nucleus.
Protein: GCSPA_ERYLH
Sequence: MRYLPLTDTDRSEMLSVVGASSIDDLFVDVPKEARLDGPIRDLPMHASEMAVEKHMRARAAKNLVAGDVPFFLGAGAYRHHVPASVDHIIQRGEFLTAYTPYQPEIAQGTLQMLFEFQTQVAKLYGCEVANASMYDGSTACWEAISMASRVTKRNRAVLSGALHPHYSEVAKTMAKYLGLEIADAQPAIQAAPDNAGLTSRIDENTSCVVVQYPDILGRIADLTEIAEAAHAKGALLIVVNTEPVALGAIKSPGEMGADIVVGEGQSLGVGLQFGGPYLGLFAVRDKKHVRQMPGRLCGETVDAEGKRGFVLTLSTREQHIRREKATSNICTNSGLCALAFSVHMTLLGEVGLRRLAAENHRLACLTADRLAKVPGVTVLNDTFFNEFTIQVGQDAREIVRTLADKGVLAGVSLGRLYPDVERLSDALIVATTETTSEDDIEALGSALEEVLA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: RIMP_CLOD6
Sequence: MKKNLEATIEEIVTKITDEHGFEMVDVEYVKEAGEYYLRVYIDKEEGISLNECELVSRELSPILDEKDPIKENYFLEVSSPGLDRALKKDRDFVRYQGRDVDLKLYKPLNGCKQFEGELVGLTEDNNIKIIANGKEMEFNRKDVAIVRLAIKF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURB_METPB
Sequence: MTAHSLIDDIRAAAPDLRGRLLENQSLSDLTWFRVGGPAQVLFSPADEEDLAAFLAALDPSVPVTVIGLGSNLIVRDGGIPGVTIRLGGKAFGSVEIDGETIRAGTAVPDMRLAKAAAEASLDGLAFFRGIPGSVGGALRMNAGAHGGETTDVLTEARGIDRNGAVRSFTHAEMGFRYRHSSAPDDVIFTSATFRGRPGDREGIEAEMERVTAAREAAQPIRERTGGSTFKNPKGGKAWQLIDAAGCRGLIRGGAQVSEMHCNFLINRGGATAADIEGLGEEVRRRVREHSGFELHWEIKRIGVESSEG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_BACCQ
Sequence: MLTERQLLILQTIIDDFIGSAQPVGSRTLAKKDEITFSSATIRNEMADLEELGFIEKTHSSSGRVPSEKGYRFYVDHLLAPQNLPNDEIVQIKDLFAERIFEAEKIAQQSAQILSELTNYTAIVLGPKLSTNKLKNVQIVPLDRQTAVAIIVTDTGHVQSKTITVPESVDLSDLEKMVNILNEKLSGVPMSELHNKIFKEIVTVLRGYVHNYDSAIKILDGTFQVPLSEKIYFGGKANMLSQPEFHDIQKVRSLLTMIDNEAEFYDILRHKQVGIQVKIGRENSATAMEDCSLISATYSIGEEQLGTIAILGPTRMQYSRVISLLQLFTRQITDGLKK
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: LNX1_MOUSE
Sequence: MNQPDLADDPDPSPEPLCIVCGQNHSPEENHFYTYTEDVDDDLICHICLQALLDPLDTPCGHTYCTLCLTNFLVEKDFCPVDRKPVVLQHCKKSSILVNKLLNKLLVTCPFTEHCTEVLQRCDLQHHFQTSCKGASHYGLTKDRKRRSQDGCPDGCASLMATTLSPEVSAAATISLMTDEPGLDNPAYVSSVEDGEPVANSSDSGRSNRTRARPFERSTMRSRSFKKINRALSALRRTKSGSVVANHVDQGRDNSENTTVPEVFPRLFHLIPDGEITSIKINRADPSESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVLRLTVLREQKFRSRSNAHVPDSYGPRDDSFHVILNKSSPEEQLGIKLVRRVDEPGVFIFNVLNGGVADRHGQLEENDRVLAINGHDLRFGSPESAAHLIQASERRVHLVVSRQVRQSSPDIFQEAGWISNGQQSPGPGERNTASKPAATCHEKVVSVWKDPSESLGMTVGGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVNGIELTEVSRTEAVAILKSAPSSVVLKALEVKEQEAQEDCSPAALDSNHNVTPPGDWSPSWVMWLELPQYLCNCKDVILRRNTAGSLGFCIVGGYEEYSGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARMLKELKGRITLTIASWPGTFL
What is the function of this protein?
Isoform 2 provides an endocytic scaffold for IGSF5/JAM4.
What are the official names of this protein?
E3 ubiquitin-protein ligase LNX, Ligand of Numb protein X 1, Ligand of Numb-binding protein 1, Numb-binding protein 1, RING-type E3 ubiquitin transferase LNX.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AKA7G_HUMAN
Sequence: MERPEAGGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGITDEPQINLKRSQENEWVKSDQVKKRKKKRKDYQPNYFLSIPITNKEIIKGIKILQNAIIQQDERLAKAMVSDGSFHITLLVMQLLNEDEVNIGIDALLELKPFIEELLQGKHLTLPFQGIGTFGNQVGFVKLAEGDHVNSLLEIAETANRTFQEKGILVGESRSFKPHLTFMKLSKSPWLRKNGVKKIDPDLYEKFISHRFGEEILYRIDLCSMLKKKQSNGYYHCESSIVIGEKNGGEPDDAELVRLSKRLVENAVLKAVQQYLEETQNKNKPGEGSSVKTEAADQNGNDNENNRK
What is the function of this protein?
Probably targets cAMP-dependent protein kinase (PKA) to the cellular membrane or cytoskeletal structures.  The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium.
What are the official names of this protein?
A-kinase anchor protein 7 isoform gamma, AKAP-7 isoform gamma, A-kinase anchor protein 18 kDa, AKAP 18, Protein kinase A-anchoring protein 7 isoform gamma, PRKA7 isoform gamma.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: TRI10_PIG
Sequence: MASAASVSSLADEVNCPICQGTLREPVTIDCGHNFCCVCLTRYLEIPCLDPGELPTCPLCKEPFRPGSFRPNWQLASVVENIERLKLGSQLGSEEEEDVCLEHREKVYYFCEDDEMQLCVVCREAWEHRHHTVRFLEDAAGPYREQIQKCLECLRKEGEEIQRIQLRENQRIQVLLTQVATKKQKVISEFAHLSQFLEEQQSVLLAQLERLDGDILKHRDEFDVLVAGEICRFNTLIEELEEKNQRPARDLLTDIRSTLIRCETRRCRKPEAVSPELGQRIRDFPQQALPLRREMKTFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDNQQARFSYKWQNSPDNPQRFDRATCVLAHSGFTEGRHTWVVSVDLAHGGSCTVGVVSQDIRRKGELRMRPEEGVWAVRLAWGFVSALGSFPTRLALEEHPRQVRVSIDYEVGWVTFVNAVTQEPIYTFTASFTQKVFPFFGLWGRGSKFSLSS
What is the function of this protein?
E3 ligase that plays an essential role in the differentiation and survival of terminal erythroid cells.  May directly bind to PTEN and promote its ubiquitination, resulting in its proteasomal degradation and activation of hypertrophic signaling (By similarity).  In addition, plays a role in immune response regulation by repressing the phosphorylation of STAT1 and STAT2 in the interferon/JAK/STAT signaling pathway independent of its E3 ligase activity.  Mechanistically, interacts with the intracellular domain of IFNAR1 and thereby inhibits the association of TYK2 and IFNAR1 (By similarity).
What are the official names of this protein?
Tripartite motif-containing protein 10, B30-RING finger protein, RING finger protein 9.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSL44_DICDI
Sequence: MTLFSSISSISSSISSSKSSIASFGNGTSMGSNSIACGGGCGSGNGFGGIFIGANIDLTGGASTSSGGRGGRPGRGHGGPHGHGRGGSGSGSSCGCN
What are the official names of this protein?
HssA/B-like protein 44.
What is the protein family that this protein belongs to?
Belongs to the hssA/B family.
Protein: MNMG_PARD8
Sequence: MTFNYDVIVVGAGHAGCEAAAAAANLGSKTLLITMDMNKIAQMSCNPAVGGIAKGQIVREIDALGGYMGIVTDQTAIQFRMLNRSKGPAMWSPRAQSDRARFIDCWRGILENMPNLSIWQDMVQELIIEHGQVCGVRTGMNVVFRAGAVVLTNGTFLNGLLHIGRTQIRGGRIAEPAATGLTEQLISLGIQTDRMKTGTPVRIDGRSVHFDEMEEQPGENDFHKFSYMDTSHRKLKQLSCWTTFTNEACHDILREGLPDSPLYNGQIKSIGPRYCPSIETKIVTFADKTQHQLFLEPEGEATQEYYLNGFSSSLPLDIQLRALQAIPAFRDVQIYRPGYAIEYDFFDPTQLRHNLETKQIRNLFFAGQINGTTGYEEAGGQGLVAGINAHINCHGGQPFILGRDEAYIGVLIDDLVTKGVDEPYRMFTSRAEYRILLRQDDADMRLTEKSYQMGLAKQDRYDLLREKKESRDAIIRFAETYSVKPQYINSGLEKLGTAPLSHGCKLFDVVLRPQTTLENLADLVPALRAELDKVPASRKEEIIEAAEILIKYSGYIKREQIIADKINRLENIRIKGKFDYNSIQSLSTEARQKLTRIDPDTIAQASRIPGISPSDINILLVLLGR
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIN1_RAT
Sequence: MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTYLASVKAMHEASKKLSECLQEVYEPEWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEKAAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVSLEKQHGSNTFTVKAQPSDSAPEKGNKSPSPPPDGSPAATPEIRVNHEPEPASGASPGATIPKSPSQLRKGPPVPPPPKHTPSKEMKQEQILSLFDDAFVPEISVTTPSQFEAPGPFSEQASLLDLDFEPLPPVASPVKAPTPSGQSIPWDLWEPTESQAGVLPSGEPSSAEGSFAVAWPSQTAEPGPAQPAEASEVVGGTQEPGETAASEATSSSLPAVVVETFSATVNGAVEGSTTTGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVQ
What is the function of this protein?
Is a key player in the control of plasma membrane curvature, and membrane shaping and remodeling.  Required in muscle cells for the formation of T-tubules, tubular invaginations of the plasma membrane that function in depolarization-contraction coupling.  Required in muscle cells for the formation of T-tubules, tubular invaginations of the plasma membrane that function in depolarization-contraction coupling (By similarity).  Is a negative regulator of endocytosis (PubMed:9736607, PubMed:27760323).  Is also involved in the regulation of intracellular vesicles sorting, modulation of BACE1 trafficking and the control of amyloid-beta production (By similarity).  In neuronal circuits, endocytosis regulation may influence the internalization of PHF-tau aggregates (PubMed:27760323).  May be involved in the regulation of MYC activity and the control cell proliferation (By similarity).
What are the official names of this protein?
Myc box-dependent-interacting protein 1, Amphiphysin II, Amphiphysin-like protein, Bridging integrator 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Endosome. Cell membrane, sarcolemma, T-tubule.
Protein: GLO2_ECOLC
Sequence: MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAIAANNWQPEAIFLTHHHHDHVGGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEFSVIATPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTASQMYQSLKKLSVLPDDTLVCCAHEYTLSNMKFALSILPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLRTEDIDLINVINEETLLQQPEERFAWLRSKKDRF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: RBL_SESIN
Sequence: DILAAFRVTPQPGVPPEEAGXXVAAESSTGTWTTVWTDGLTSLDRYKGRCYNIEPVPGETDQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPTAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRACYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMMKRAIFARELGVPIIMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMXFRVLXKALRMSGGDHIHSGTVVGKLEGERDITLGFVDLLRDDFVEKDRSRGIYFTQDWVSLPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALXXXXXXXNXGXDLAAEGNAIIREASKWSPELAAACEVWKEIKFKFKAVDTLDK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y686_ARCFU
Sequence: MSEKTHWNRREMAEKGFTFVFPYSEGLKRVRELLNTDYDPAVLWVWGTMQARAVIETLKACESDFGEKGQKVVYEALKKVGREVAEQMISSSKFEGMDEAELLSFFATIVNTIAYASIEKPWVESEERVGFDILWCPHQDVYSAFDCRVQRYFVQGMLEALREKYEKETGKKLKWQVKFETTIPAGADVCRFVIWRSESEDNEWEKYTELLNRKALNGKNIL
What are the official names of this protein?
Uncharacterized protein AF_0686.
Protein: TMX2_MOUSE
Sequence: MAVLAPLIALVYSVPRLSRWLARPYCLLSALLSIAFLLVRKLPPICNGLPTQREDGNPCDFDWREVEILMFLSAIVMMKNRRSITVEQHVGNIFMFSKVANAILFFRLDIRMGLLYLTLCIVFLMTCKPPLYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYNCSGLNFGKVDVGRYTDVSTRYKVSTSPLTRQLPTLILFQGGKEVIRRPQIDKKGRAVSWTFSEENVIREFNLNELYQRAKKHSKGGDMSEEKPVDPAPTTVPDGENKKDK
What is the function of this protein?
Endoplasmic reticulum and mitochondria-associated protein that probably functions as a regulator of cellular redox state and thereby regulates protein post-translational modification, protein folding and mitochondrial activity.  Indirectly regulates neuronal proliferation, migration, and organization in the developing brain.
What are the official names of this protein?
Thioredoxin-related transmembrane protein 2, Thioredoxin domain-containing protein 14.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Mitochondrion membrane. Note=Localizes to endoplasmic reticulum mitochondria-associated membrane (MAMs) that connect the endoplasmic reticulum and the mitochondria.
Protein: HIS2_GEOMG
Sequence: MNERDDILQAVYRVIKERKGASADSSYTASLLQKGIDKILKKLGEEATEVVIAGKGGKREEIVYETADLFFHTLVLLGYYDIDPEEIYAELRRRFGTSGIAEKASRPKE
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.