PharMolix/UniProtQA huggingface dataset:
Protein: POL2_BRAV
Sequence: MSESGNTTSMPGCGRMCALRSTWSKRAFLVACKDGALTSDGRCPQYGCGALVSITKGVQQPKKTASAKVVKCLCWVQPARWCEKHSKGPASPNGSVTTKRSNSARAAPAPLPYKKQTCDVVVTVGPLELVYPALVSEELPTPVAATPTKVEEVPIPELPLWLAPAWMVEQPYAATPEVLCLTQREEFALLKKRLTRKGKLLQRRATHARFEARAALARVRAATQRKVEEVTALVIKGRRILAAHQLLRELEEVAPLSQAQEQLVASSCAAAAARQEECASFLRRAKAWRKSISATPPVAFATAVASKVVSATMPWAHLGLSLGGLLAVPTLDGTLGAKQWNAKTIATWVLKPVVSCVQSVHAKVRDWLHSQPEVGVTNTKVPLVLPEVCLGVLSPPSLSEEIVDNPQETSQSGIWHPEMGVRNIYVFHDDSWETSPEEDENYTYTFSRQCGIPYLLVEGRGAEERKNTILGWDFSLHNDGEFEFLPSPEEGYTKELVTPVALEEEDKYSTASSCGFFSLDDVSSAITIQCPGLLSADADVHFFDGPGYRCSSRPRDFRPPVVRGCDYESRVKASIQRKIENPLQERFITVLREKRKKNKKKEFHSFSACFAFKRKQIQWPPTPNEMVNEWEEYCIAQAWLPFEVVVTDEIEDVTPLYPGGRDYNCNSQLLFPLAPLSTVYCDDSCFHPNDGWTTDGNGKHFRLSPQFVLPDVPIPIVHRVTRQLPQFLYDLGIGDLTCNSGYQAENLQEEIQERMEDRSEEKPVPSLDTLISKLSKRSTKVKGAGENRYADRHSLTEKAIFHQPGALSRMRSGKEKTIVAANHNSDQISVRMAECGKPVFTPLPRMSDEMLRKFLEKGLGSTSTVALDIGIQSHIPQGMPTVAFVNVMDTRIEDPLYSSLCGSYIDLGRDRAKTLCLPLVNFPMSKLAEDVDDVLNGLMLCTHFQDSTKFGVGKPAFQYGTLEFQEFKPSAYSDFSRVRDNWDAIAKQQNTPNDRILAGFSVLGAVSQAYNQALPVFKSVELVAPPKRKPVVATFQNPTTLGRSNTTRSFRMPTMDLPRSTGRDAPIPIVHRRNNNDVHGFDEATPARFSTCDSGLVADTTLAFAKMYQCKKDAKAGHVLATIDIQECVFEDNRRVALDWLAHGLASFKYDLQLTVDSNPFVGVTLGITVDAFDRLLPQISDEVIAVPLAFQLPTYLFPISKKGTFTQTIDFAAIAGYNFFPHVAAFGRPKIIVYIVSDNDLPASDTWMCLVELHMTRLESSTLACSPTLVLPQAFGGDLPLDLWRGPYTFPLGGGTKRLSTSLDIGTSTTTVSGWRTVSFPAAYALFLQGHGGSLVGEVVHTGSAAVSCALHLCISFGGAPPTLEEALVFPGFRLPSGEGKFHIKVQTPYGRLSTLTPDCALYVYLAGGPIAVAPMSVPYQFCIHLERLVDDGAPPRTIGLIREFNWATINNFKSDDITFAIPARLSDLVLTCGDVTMSTNPLALLIGSCGFFRGNLTVVLEWATFLKAGDKEGTVQLTTCRGMINNVKGVRNAIQKKVVNLSLVGSVSRYLNVGDFTGFAQSGGQVGYDEIFLEFSTNKAKQIRYLNINVELDENFELYGRTIIPLKNTAPAFASTSASAPNES
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Acts by forming a tubular structure at the host plasmodesmata, enlarging it enough to allow free passage of virion capsids (By similarity).
What are the official names of this protein?
RNA2 polyprotein, P2.
What is the protein family that this protein belongs to?
Belongs to the nepoviruses RNA2 polyprotein family.
What are the subcellular locations of this protein?
[Movement protein]: Host cell junction, host plasmodesma. Note=Assembles in tubules that are embedded within modified plasmodesmata. SUBCELLULAR LOCATION: [Coat protein]: Virion.
Protein: TSX_MOUSE
Sequence: MSEKQSPKTSEAECSAMDLPEFEDEENWLFKVLGFQPGPSSALDDDTDDQADEPLSAAEFLHLQDILQEDRVSSTDDEDTCQAGCTEDDETSHSDRDIDNNVKVITGNIKASPSMYMEMFTDQNPQADQDLEETESDGAMNPTD
What is the function of this protein?
May have an RNA/DNA binding role.
What are the official names of this protein?
Testis-specific protein TSX.
Protein: COE1_RAT
Sequence: MFGIQESIQRSGSSMKEEPLGSGMNAVRTWMQGAGVLDANTAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVGFVEKEKEANSEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMTKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEAATPCIKAISPSEGWTTGGATVIIIGDNFFDGLQVIFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIYTALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVILKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHNQLPALANTSVHAGMMGVNSFSGQLAVNVSEASQATNQGFTRNSSSVSPHGYVPSTTPQQTNYNSVTTSMNGYGSAAMSNLGGSPTFLNGSAANSPYAIVPSSPTMASSTSLPSNCSSSSGIFSFSPANMVSAVKQKSAFAPVVRPQTSPPPTCTSTNGNSLQAISGMIVPPM
What is the function of this protein?
Key pioneer transcription factor of B-cell specification and commitment.  Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'.  Operates in a transcription factor network to activate B-cell-specific genes and repress genes associated with alternative cell fates.  For instance, positively regulates many B-cell specific genes including BCR or CD40 while repressing genes that direct cells into alternative lineages, including GATA3 and TCF7 for the T-cell lineage.  In addition to its role during lymphopoiesis, controls the thermogenic gene program in adipocytes during development and in response to environmental cold.
What are the official names of this protein?
Transcription factor COE1, O/E-1, OE-1, Early B-cell factor, Olf-1, Olfactory neuronal transcription factor.
What is the protein family that this protein belongs to?
Belongs to the COE family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KAISO_MOUSE
Sequence: MESRKLISATDIQYSASLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTYFHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKVVRVRADLLDELIKSGQLLGVKFIAELGVPLSQVKSISGTEQDGTAETLPSSSSDKSLDMEKSKDEAQDNGATVMPIITESFSLSAEDNEMKKIIVTDSDDDDDDDVIFCSEILPAKEDLPSNNTATQVQPNPASVAISEVTPCASNNSPPVTNITPTQLPTPVNQATLSQTQGSEELLVSSASTHLTPNIILLNQAPLTAPPSASSSLPNHMSSSVNVLVQNQQTPNSAVLTGNKAEEEEEIIDDDDDIISSSPDSAVSNTSLVPQADNSKSTTLDGSLTQKMQIPVLPQEPPSNSLKISDVITRNTNDPGLRSKHVMEGQKIITLDTATEIEGLSTGCKVYANIGEDTYDIVIPVKDDPDGGEAKLDNELPKTSGSEPPNKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNIHSWEKKYQCRYCDKVFPLAEYRTKHEIHHTGERRYQCLTCGKSFINYQFMSSHIKSVHSQDPSGDSKLYRLHPCKSLQIRQYAYLSNKSSAMPVMKDDAVGYKVDAGKEPPVGTTSTPPQNKSTFWEDIFIQQENDSIFKQNVTDGSTEFEFIIPESY
What is the function of this protein?
Transcriptional regulator with bimodal DNA-binding specificity.  Binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS).  May recruit the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters.  Contributes to the repression of target genes of the Wnt signaling pathway.  May also activate transcription of a subset of target genes by the recruitment of CTNND2.  Represses expression of MMP7 in conjunction with transcriptional corepressors CBFA2T3, CBFA2T2 and RUNX1T1 (By similarity).
What are the official names of this protein?
Transcriptional regulator Kaiso, Zinc finger and BTB domain-containing protein 33.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYS_METI4
Sequence: MLDIQLIRHNLAQTKQKLALRSKGLETLLDHIFELDFKKRSLQSEIEKYRALRNKQSKEIGLKKIKGENVEGQFSELKKMGSRIEEMEKELIQFENQINTLLLSLPNIPHDSVPTGGPEANKVVKTWGEPRQANFPLKTHWELGRELGILDLERGAKLSGSGFSLFTGNGAKLQRALIQFMLTIHTEEHGYKELWPPYLVTEDCMRGTGHLPKFALDMYATDKDNLYLIPTGEVPLTNFHRDEILAESSLPLRYVAYTPCFRREAGSAGKDTRGLLRLHQFDKVELVQITKPENSYTALEEMVSHAENILRSLNLCYRVVLLASQDMGFGAAKCYDLEVWSPGIQSWLEVSSVSNMENFQSRRMNLRYKSSSGKNILCHTLNGSGTALPRLVAAILENYQKEDGRVLIPEKIRTYFKEEYL
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UCN3_BOVIN
Sequence: MLVPAPFLLVLLLLLGAPQVGLSQRSPKAGSSPSCLHTALREAEKSQRKDTSLLIKRTFPALPRGDPEDQEGQEEEDTEKRTFPGSVGGGGGGGAGSTRYKYPSQAQFQGRPSQDKAKSDRRTKVTLSLDVPTNIMNILFNIAKAKNLRAKAAANAHLMAQIGRKK
What is the function of this protein?
Suppresses food intake, delays gastric emptying and decreases heat-induced edema.  Might represent an endogenous ligand for maintaining homeostasis after stress (By similarity).
What are the official names of this protein?
Urocortin-3, Urocortin III, Ucn III.
What is the protein family that this protein belongs to?
Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
What are the subcellular locations of this protein?
Secreted.
Protein: PEPT_STRP6
Sequence: MKYDNLLDRFIKYVKVNTRSDPDSETTPSTESQEAFALTILKPEMEAIGLQDVHYNPVNGYLIGTLPANNPTLTRKIGFIAHMDTADFNAENVNPQIIDNYQGEDITLGSSNYKLDPKAFPNLNNYIGQTLITTDGTTLLGADDKSGIAEIMTAIEFLTSQPQIEHCDIKVAFGPDEEIGVGADKFEVADFEVDFAYTMDGGPLGELQYETFSAAALEVTFLGRNVHPGTAKDQMINALQLAIDFHEKLPAKERPEYTDGYQGFYHLTGLTGTVEEARASYIIRDFEEASFEARKVKVENIAQSMNAQLGTKRVLVELNDQYYNMKKVIEKDMTAIELAKEVMEELTIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQTMERAVDVIIGLVCKA
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAV2_SAIBB
Sequence: MGLETEKADVQLFMDDDSYSHHSGLEYADPEKFVDSGQDRDPHRLNSHLKLGFEDVIAEPVTTHSFDKVWICSHALFEISKYVMYKFLTVFLSIPLAFLAGILFATLSCLHIWIIMPFVKTCLMVLPSVQTIWKSVTDAIIAPLCTSIGRSFSSVSLQLSHD
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes.  Interacts directly with G-protein alpha subunits and can functionally regulate their activity.  Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation.  The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells.  Positive regulator of cellular mitogenesis of the MAPK signaling pathway.  Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity).
What are the official names of this protein?
Caveolin-2.
What is the protein family that this protein belongs to?
Belongs to the caveolin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Note=Potential hairpin-like structure in the membrane. Membrane protein of caveolae. Tyr-19-phosphorylated form is enriched at sites of cell-cell contact and is translocated to the nucleus in complex with MAPK1 in response to insulin (By similarity). Tyr-27- phosphorylated form is located both in the cytoplasm and plasma membrane. CAV1-mediated Ser-23-phosphorylated form locates to the plasma membrane. Ser-36-phosphorylated form resides in intracellular compartments.
Protein: RPOD_RICPR
Sequence: MSNSNIDNDPAKIDSLLKKAKSKKIPVTYDDINKALPLNKNPSIRQLEEAILKFSDAGVDILESNEDDEIKLDIGMDEEFKLSTNVDNESEDEVEEENIGSTDDPVRLYLKDMGGVDLLTRENEVEIAKRIEEGRKTMTASLCRSPIAMRCFIVWYEDLVNEKMLLRDLIDLEANMLHDEVHENDEEHNSETEVEEHEDNHLSMSRVETQILHNIIDRMKKISFICEELLIEAKKCYEESFEPKVLQNSKKYNNNLELLINEVSEIHFNSKRTEEILGKMYGINRDLINKETAFLKLAEKYGVTRQNFLDEYIGSVINAAWKEKMLKNKKVAWKELITKESDYIDQMINELSVIESNTGLLVNDFKKLVNTIQKSERQTLQAKKDMIEANLRLVISIAKKYANRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRAIADQARTIRIPVHMIETINKILRTSRQMLNELGYEPTATEIANRLSMPLDKVRKVMKIAKEPISLENPVGDDSDGGQLGDFIEDKNAVAPIDAAIQSNLREVTTRVLATLTPREERVLRMRFGIGMNTDHTLEEVGQQFKVTRERIRQIESKALRKLQHPIRSKKLNSFRNGGKRGDGNPSDLLEA
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is the primary sigma factor during exponential growth.
What are the official names of this protein?
RNA polymerase sigma factor RpoD, Sigma-70.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CXL11_BOVIN
Sequence: MSVKGMAIVLTVILCAAIVQGFPMFKGGRCLCIGPGVKAVKVADIEKVSIIYPTNNCDKTEVIITLKTHKGQRCLNPKAKQAKAIIKKVQRKNSEKYKNI
What is the function of this protein?
Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes.  Induces calcium release in activated T-cells.  Binds to CXCR3.  May play an important role in CNS diseases which involve T-cell recruitment.  May play a role in skin immune responses (By similarity).
What are the official names of this protein?
C-X-C motif chemokine 11, Small-inducible cytokine B11.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: IFNA4_MOUSE
Sequence: MARLCAFLMILVMMSYYWSACSLGCDLPHTYNLGNKRALTVLEEMRRLPPLSCLKDRKDFGFPLEKVDNQQIQKAQAILVLRDLTQQILNLFTSKDLSATWNATLLDSFCNDLHQQLNDLKACVMQEPPLTQEDSLLAVRTYFHRITVYLRKKKHSLCAWEVIRAEVWRALSSSTNLLARLSEEKE
What is the function of this protein?
Produced by macrophages, IFN-alpha have antiviral activities.  Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
What are the official names of this protein?
Interferon alpha-4, IFN-alpha-4.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: PRMA_PROM2
Sequence: MEIKDWYKLTFQIESDSEDIIIWKLNELGIFSFSFEYLIKNQNKKEVNIWLPFDSWDNNSRSDFEKIISKILKINDSKNKFFNWSIIKEEDWLTSWKKFWAPELVGNHFLILPCWINLNEKFKDKQIIKIDPGAAFGTGSHPSTYLCLEKMENILFSDKKVLDIGSGSGILSIAARLGGAKEVCAVDNDYLAINSTNSNFQLNFGNLNNLNTYLGSFNEVILKNQLKQFDFVLCNILAEVIKGMIPNIYKCLRNNGEVIFSGILNSQKDEIIKILIQNNLKLLDVSSRKNWACISAQKPASNPKHKIYL
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSG_STRP8
Sequence: MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIPTQTVNVEKNGQTKEIEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPTPLLEEEIRAILLSMGQTIDVFDTNIKEGDVVQIIDGAFMGQEGRVVEIENNKVKLMLNMFGSETVAEVELYQIAEL
What is the function of this protein?
Participates in transcription elongation, termination and antitermination.
What are the official names of this protein?
Transcription termination/antitermination protein NusG.
What is the protein family that this protein belongs to?
Belongs to the NusG family.
Protein: OCA5_CANAL
Sequence: MLQTSKGSNSSSTSSSRSASISTATPNTIVEDEELLCDPKSELTPPAVANPLRPVSKSNTSVEDDSKPSFTYDLDVFNLCKEYLNTRNHHGLALIARQKGIPPILRFKVWPILLKSHPFVISPFIQPDSELLNESTSSRSNSSSSSTGSNTPLSTAPGSIKDAAIIDGDANDNDNDSNSNSNDDDNDRDDNDANTKEKEEDERNNKIREKIKRDLAKYIQRLKYSQSKYTVSETEHEILSILENAIMKFTLKWGKIIKYDSSLTWIALNLAEWFPPIPKTPWVLVGKEYSSSHQSLIVNFLDDYSNYIDNIPDLREYLERLIYHDEKISTISFREVYERLVLVLLHCPQPVSRRKKSDNQGSNQRRNQSEVQKDQQSFKVNKTTLPKTGGTIEERVSYFIYCLRKLIPELSQYFHEEQILTKFGCLDDEWLIWWLKFCGTKVWSKYDRGRIWDFMLGWRLKNPKRDFNYYYEKLNYVNRNTLEKLGPDIFWSVGNEEEDISGDNNVDANANEINNTEKTETGKLVKREGDIKRSSFKDLVNELSNELHISKRVSTDEVATSTSSPATTKMASSSSTSSTLTPNVSIPFSRVDPHVALIFISLSLLKSKENILVELDQHEIRQFLSRLPSKSYKYNQKRSTRQKRTSYASNASSTSNSPMGQSPVDRDEDSIFPTSRIVISNDSKDQKHKVNFIDNIISEAGELWRKWLWSEMVEDN
What are the official names of this protein?
Oxidant-induced cell-cycle arrest protein 5.
What is the protein family that this protein belongs to?
Belongs to the OCA5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_RALPJ
Sequence: MSRKYFGTDGIRGRVGESPITPDFVLRLGYAAGRVLAHGGEAHGHGRPTVLIGKDTRLSGYMLEAALEAGFTAAGVDVLMSGPLPTPGVAYLTRALRLSAGVVISASHNPYYDNGIKFFSATGDKLPDETELQIEAELEKPMAYAASDALGRARRIEDAAGRYIEFCKSTFPSDLNLFGMKVVLDSAHGAAYHIAPHVFHELGADVVSIGNQPNGRNINDGYGATAPGKLVEATREHGADIGLAFDGDADRLQVVDRNGRLYNGDELLYVMVQARRAAGQTVPGAVGTLMTNLAVELALKAQGVEFVRAKVGDRYVLEELKKNGWLLGGEGSGHLLCLDKHSTGDGIISALQVLAALRRSGQTLDEMLDGVRLFPQKLINVRVEKGFDWKSHAGLQAALKTSEAELDGKGRVLIRPSGTEPVVRVMVEAQDAELANQHAERLAATLQ
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: MFSD1_BOVIN
Sequence: MEDEEEEARALLPGGSDEAGRETRAPPAASGALQALCDPSHLAHRLVVLLLMCFLGFGSYFCYDNPAALQIQVKRDMQVNTTKFMLLYAWYSWPNVVLCFFGGFLIDRVFGIRWGTIIFSCFVCIGQVVFALGGIFNAFWLMELGRFVFGIGGESLAVAQNTYAVSWFKGKELNLVFGLQLSMARIGSTVNMNLMGWLYSKVEASLGSAGHTTLGVTLMIGGITCILSLVCALALAYLDQRAERILHKEQGKTGEVIKLTDVKDFSLPLWLIFIICVCYYVAIFPFIGLVKVFFTEKFGFSSQAASAINSVVYVISAPMSPIFGLLVDKTGKNIIWVLCAVVTTLASHIMLAFTLWNPWIAMCLLGLSYSLLACALWPMVAFVVPEHQLGTAYGFMQSIQNLGLAVISIIAGMILDTRGYLFLEVFFIACVSLSLLSVVLLYMVNHAQGGNLNYSAKKREEMKLSHEE
What is the function of this protein?
Lysosomal transporter which is essential for liver homeostasis.  Required to maintain stability and lysosomal localization of GLMP.
What are the official names of this protein?
Major facilitator superfamily domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.
Protein: PDH_ROMMI
Sequence: MTAMAVSGKLLTALVLSTYILGLALTIQATQYEEDKYQENEVKYGRELASWLAQLAHKNEPAICAHKRNSEIINSLLGLPKLLNDAGRK
What is the function of this protein?
Capable of inducing pigment dispersion in the chromatophores of the fiddler crab Uca pugilator.
What are the official names of this protein?
Pigment-dispersing hormone peptides.
What is the protein family that this protein belongs to?
Belongs to the arthropod PDH family.
What are the subcellular locations of this protein?
Secreted.
Protein: NARU_SALTY
Sequence: MTRQNENYNRYLLSDWRPENPAFWENKGKGIARRNLWISVSCLLLAFCVWMLFSAVAVNLNKIGFNFTTDQLFLLTALPSLSGAILRVPYSFMVPLFGGRKWTVLSTVILIIPCAWLGFAVQNPATPFGVFMLIALLCGFAGANFASSMGNISFFFPKARQGSALGINGGLGNLGVSVMQLIAPLVIFLPIFTFLGVQGVPQPDGSLLALTNAAWIWVPLLAVATLAAWFGMNDIGSSKASVASQLPVLKRLHLWLLSLLYLATFGSFIGFSAGFAMLAKTQFPDVNILQLAFFGPFIGALARSAGGVISDKFGGVRVTLINFIFMALFTALLFLTLPGSGAGSFSAFYLVFMGLFLTAGLGSGSTFQMIAVIFRQITLYNVKLRGGSDEQAQREAVTDTAAALGFISAIGAVGGFFIPKAFGTSLALTGSPVGAMKIFLLFYLACVLLTWLVYGRRKPKQQ
What is the function of this protein?
Catalyzes nitrate uptake, nitrite uptake and nitrite export across the cytoplasmic membrane.
What are the official names of this protein?
Nitrate/nitrite transporter NarU, Nitrite extrusion protein 2, Nitrite facilitator 2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS1_ECOSM
Sequence: MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFGGCRLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMEESKQQLIDKLLTRIQGVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQQRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREE2_PSESM
Sequence: MLVIHNRIEPQAEWAAELHLNFEARSKSRLRCFSAENEDVGLFLQRGQSPLRDGEFLQAEDGRIVRVCARPEKLMHVTCSSTFELTRAAYHLGNRHVALQVGDGWLRLLDDYVLKAMLDQLGATTEAIEAPFQPEHGAYGGGHHHSRAGEEDFNYPPRMHQFGVRK
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE 2.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DOF12_ARATH
Sequence: MLPYIGHNSYQQHQFPLPEMEIPEKWKLSYEQEAITAPACPRCASSNTKFCYYNNYSLSQPRYFCKGCRRYWTKGGSLRNIPVGGGCRKRSRSRQNSHKRFGRNENRPDGLINQDDGFQSSPPGSDIDLAAVFAQYVTDRSPSSTDNTTGSDQDSPITTTTHALESLSWDICQETDVDLGFYGEFNNLTQKTKEDQEVFGQFLQEDREEIFEFQGLLDDKEIQEILECSFSEEPDQLVSQGSFMINGDNWSSTDLTRFGI
What is the function of this protein?
Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence.
What are the official names of this protein?
Dof zinc finger protein DOF1.2, AtDOF1.2.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYSG_NITOC
Sequence: MQYLPIFLNIRGQQCLVVGGGTVAVRKVALLRQAGAEVKVIAPKLHEQLQEWADKGKITAQQASFSETEIKSCYLVIAATDDSSLNEQVYHLATAQGVLVNVADCPRFCDFILPSIVDRSPVIVAVSSGGASPVLARLLRARLETLIPQAYGRLGQFAARYRSRIKQRITGIRARRIFWEKVLQGSIAERIFAGQEEEAEGALEAALEGGFVPEQGEVYLVGAGPGDPDLLTFRALRLMQQADVVFHDRLVSPEVLALVRREAERIYVGKKRSWHAVRQEEINMMLVRSAREGKRVLRLKGGDPFIFGRGGEEIATLAAENIPFQVVPGITAASGCASYAGIPLTHRDHAHACIFVTGQLKEGRLSLNWQALVQPQQTIVVYMGLSGLEILCQELIAHGMPAVTPAALVQQGTTSRQRVLTGTLATLPDIVQGEDIHAPTLVIIGGVVALYPQLAWFKVPDREPLDAR
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: TY28_PITAZ
Sequence: KPWERE
What are the official names of this protein?
Tryptophyllin-T2-8, Pha-T2-8, Tryptophyllin-12.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Tryptophillin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EPL1_GIBZE
Sequence: MSSRKVRVKKLNVKTTLPVLREDQIDPNEYEALTTDNQIATGVEQAEENEYHLQTILKEAGTSNDQEIPVPPPQESDINYDDLYPVPFHKPSSYIRFSQTVEECITCLYDMTTEDDEFLKQYNSKPPATGVLSEDDFEHIMEVFEDTAAEQTPFAAVDNTVAAYDMMLPGLTHLNQSVSTDVLQHAKPVYEYWKSRRQEAGNKPLHPSLKFETHQETDDTDPFVCFRRREARQTRKTRARDNKIAETLKKLRRELEDGRQLVLLAYEREMVKREVMSMDRAIFEERARLKDMKLRLGIKGEDEDLVNQKPQKRKPVEPPVVRQPTGAHLRQPVRSDGRTLDADLVLLSDKLAEKETELRLDIEMKVQNHRKWNQNHIDLTREPLSPVKEQGTEVKFRQAKTQYLMTPPASTSSEMEVDEIAPDAMQLDKRESSVFQFTAGSGEQSKGSQPAFRRRIGRLNRLWIDRRGMVTPPRELGEDRSDRWKYDSDSDDEEPPVYEVDPFDTRALKFRATIPLNPYMFRGRPAVPPEAVAAAQAQAGNRVLPSPAAAAAHAHAQAHAQAAAAAHLAAQAQAKAQAVAQQQAQAAQGV
What is the function of this protein?
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair.  Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M (By similarity).
What are the official names of this protein?
Enhancer of polycomb-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the enhancer of polycomb family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KV6A4_MOUSE
Sequence: EIVLTQSPAITAASLGQKVTITCSASSSVSYMHWYQQKSGTSPKPWIYEISKLASGVPARFSGSGSGTSYSLTISSMEAEDAAIYYCQQWNYPLITFGGGTKLEIKR
What are the official names of this protein?
Ig kappa chain V-VI region SAPC 10.
Protein: Y4116_ARATH
Sequence: MDLSLSGGDFRFAFNNVNFSDRLLRIEITQSSGEGEVICSSIVDWARDRKRRREDVTNHTNDATCHVESDLNKNSCEIVNENSNNKTQVLVTAAEQEPKSGGEDENERLTNNNTSVLSVQELHISSAILAAKSPFFYKLFSNGMLESEQKQMTLKIDASEETAVMELLKFMYSNSLSVTASSALLDVLMVADKFEVASCMKYCSQLLLKMPMTLESSLLLLDLPSSLLMADSVKPLTNAARQFIASRYKNMSKITMEELMALPLVGIEAILASDGLEIQSEDVVYEVVLKWVKSHYSVLEARQEVLGSHLARYIRFPHMTTDRLKKILTSNDFRPSVASKLVVEALFFKTESLAHQHVLLAHEQPASTSRRFAKRAYVHRPIKIVEFAVPRPQCIIYLDLKRKECESIYPSSRISSQQFTLGGQGFFLSAQCNMDHLCLIHCFGLFIGMQENGSASASVTVDYDFSVRSKPTMEFVGKFKGIYTFTRGKAVGCRNLLGIPWDIFTAKNCPYFINDVLHLRADLSIRL
What is the function of this protein?
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
BTB/POZ domain-containing protein At4g01160.