PharMolix/UniProtQA huggingface dataset:
Protein: NUOB2_BURMS
Sequence: MANHPLTLEKDGFIVTTLDAAMAAAQKNSLWYMTFGLACCAVEMMHAAGARYDMDRFGMIPRASPRQCDLMIVAGTLTNKMAPAMRRVYDQMAEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDVYVPGCPPTAEALVYGLMQLQRKVAERSTHSRPKLFARP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B 2, NADH dehydrogenase I subunit B 2, NDH-1 subunit B 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SSTT_ACISJ
Sequence: MRWVQRTSLVTQIAIAVVIGIVLAAVWPAATPHLAILGSLFISALKAVAPVLVFVLVMSAISNHTPGETTHIRPVLVLYAVGTLAAATVGVVASMWFPSTLTLQAPAQAAAGPGSVSEVLMNVLKSVVENPVKALLEANYIGILAWAIALGLALRHASAGTRAMLQDGAAAVTQVIQLVIRLAPLGILGLVASTFAEAGAQALWGYAQLLAVLLGCMLFVALVVNPLIVYVAIRRNPYPLVLMCLRESGVTAFFTRSSAANIPINLALAKRLRLNEDTYSIAIPLGATINMAGAAITISVLSLAAANTLGIQVDLPTALLLCVVASLCACGASGVAGGSLLLIPLACSLFGIGNDVAMQVVAIGFIIGILQDSAETALNSSTDVIFTAAACLAQERKAQV
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MTND_BACLD
Sequence: MATIRIHDEQNTSIENQEEVEQFLKRQEVIYEKWDITKLPAGLKEKYDLTDEEKQEILDVFAAEIKDISERRGYKASDVISLSDQNPKLDELLKNFKQEHHHTDDEVRFIVSGHGIFAIEGKDGTFFDVLLNPGDLISVPENTRHYFTLQEDRKVVAVRIFVTTEGWVPIYEKENVNQS
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: PUR2_DICDI
Sequence: MTIKNNILVIGSGSREHAITWKLLESNQVDKVILVPGNASSSTMERVITVECSKIDAESISNICKEHNVEYVFVGPEVPLVDGIVDGLKRKGISCFGPTKKAAQLEGSKVFCKDFMARNNIPSARYQTFTDYNKAKQYIESLNYKIVLKASGCAAGKGVLIPNNKEEELEGLKRIMVDKEFGSAGDEIVIEEFLDGEECSLMCFSDGYSLVVMPPAQDHKRIFDGDKGANTGGMGAYAPAPFIVDCNNNATTDKSKSKSSFGTIIDRCVETILKPTINGMRKEGKPFVGVLFAGLMVSSSSSTTNDKVINVLEFNCRMGDPETQVVLPLLETDLFEIVLACIEGRLDGLDVKWSNKFAVTVVAASKGYPDSYPKGLKINGLLENKNTNDNIIFQAGTTVNGSNDIVTNGGRVLSCTSVSESLEDAIKNSYKLIETISFEGMQYRKDIGQKALNHLERKKQQQANSKQSVSYSESGVDIERGDAVVDNIGPLAKATTRLGCVSDLGGFGALFDTKAAGFRDPILVSGTDGVGTKLKIAQELGIHDSIGIDLVAMCVNDVVVQGAEPLFFLDYFATGRIHVDVATQVVSGIARGCKESGCALIGGETAEMPGMYKDGEYDLAGFSVGAVERDQMLPSNIQEGNILLGLASSGVHSNGYSLVRYLIETKSGGLTYNSIAPFDSSKTLGQVLLTPTKLYVLSCLAAIKSGGVNGLAHITGGGITENLPRVIPDGLDCEVELGSWEILPIFKYLVELGNMETEELLKTFNSGIGMILIVSPDKVDSITKSLESNNEKVYKIGKIINSKTSKQSKSKVIYK
What is the function of this protein?
Catalyzes the second and fifth step in the 'de novo' purine biosynthesis pathway; contains phosphoribosylamine--glycine ligase (GARS) and phosphoribosylformylglycinamidine cyclo-ligase (AIRS) activities.
What are the official names of this protein?
Bifunctional purine biosynthetic protein purD.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: TAL_CLOPS
Sequence: MKIFIDTANVEEIRKASKLGVLAGVTTNPSLIAKEGRDIKEVIEEICSIVDGPISAEVMALECDEMVREGIELAKIHKNIVIKIPMCEEGLKAVKVLASEGIRTNVTLIFSPLQALLAARAGASFVSPFLGRLDDIGNPGIEIVTQIAEMFALHGIDTEIISASVRNPMHVLDSAMAGSHIATIPYNVILQMVKHPLTDAGMKKFIEDYNKAFNK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BNZA_PSEP1
Sequence: MNQTDTSPIRLRRSWNTSEIEALFDEHAGRIDPRIYTDEDLYQLELERVFARSWLLLGHETQIRKPGDYITTYMGEDPVVVVRQKDASIAVFLNQCRHRGMRICRADAGNAKAFTCSYHGWAYDTAGNLVNVPYEAESFACLNKKEWSPLKARVETYKGLIFANWDENAVDLDTYLGEAKFYMDHMLDRTEAGTEAIPGVQKWVIPCNWKFAAEQFCSDMYHAGTTSHLSGILAGLPEDLEMADLAPPTVGKQYRASWGGHGSGFYVGDPNLMLAIMGPKVTSYWTEGPASEKAAERLGSVERGSKLMVEHMTVFPTCSFLPGINTVRTWHPRGPNEVEVWAFTVVDADAPDDIKEEFRRQTLRTFSAGGVFEQDDGENWVEIQHILRGHKARSRPFNAEMSMDQTVDNDPVYPGRISNNVYSEEAARGLYAHWLRMMTSPDWDALKATR
What is the function of this protein?
Catalyzes both the oxidation of benzene and toluene.
What are the official names of this protein?
Benzene 1,2-dioxygenase subunit alpha, Benzene 1,2-dioxygenase P1 subunit, Toluene 2,3-dioxygenase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.
Protein: THIE_LACLS
Sequence: MTNKTLDLSVYFIAGAQNFSECSLDGATQKIALIIKSGVTVYQFRDKGTIYKEQKQRLSIAQKLQKVSEEAGVSFIVNDDVELARELNADGIHIGQTDESVSKVREKVGQEMWLGLSVTKADELKTAQSSGADYLGIGPIYPTNSKNDAAKPIGIKDLRLMLLENQLPIVGIGGITQDSLTELSAIGLDGLAVISLLTEAENPKKVAQMIRQKITKNG
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: ISPD_XANC8
Sequence: MTGSVWAIVPAAGRGTRFGGAVPKQYLHAAGQPLMAYTLAALAAHPAVAGIVVAIAPDDADWPGWTAVHAKPVLTCVGGATRAASVLAGLLALPDGVRADDFVLVHDAARPNLALADLDRLLEIGRGDPVGAILAAPVRDTLKRAGDDGGIDGTEPRERLWRALTPQLFRRHQLIRGLTEASAAGVDVTDEAMAIERLGLRPLLVEGAEDNFKVTTPADLARFEFELANRDRGGASREAERSAMPSAATSVFSGARSAASGSEEV
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: HEMTB_STRMK
Sequence: MALLVWQDDLNIGIDVIDQQHRRIIEMLNHLHVAQASMQRAAVGEVIDEVVDYTMSHFAFEEELMEEAGYPFCAAHKRVHEVFIKRVSEYRMRFQAGEDISDELRTMLSRWLFNHIRGDDQAYAEQVKAHLNQFAREHQGGGWLGRTLKRFFG
What is the function of this protein?
Oxygen-binding protein.  May be involved in a storage mechanism or for delivery to oxygen-requiring enzymes.  The oxygen-binding site contains two iron atoms.
What are the official names of this protein?
Bacteriohemerythrin.
What is the protein family that this protein belongs to?
Belongs to the hemerythrin family.
Protein: H2B_LODEL
Sequence: MAPKAEKKPASKAPAEKKPAAKKTASSTDGGKKRTKARKETYSSYIYKVLKQTHPDTGISQKAMSIMNSFVNDIFERIASEASKLAAYNKKSTISAREVQTAVRLILPGELAKHAVSEGTRAVTKYSSAQN
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: POL1_TORVR
Sequence: MSSICFAGGNHARLPSKAAYYRAISDRELDREGRFPCGCLAQYTVQAPPPAKTQEKAVGRSADLQKGNVAPLKKQRCDVVVAVSGPPPLELVYPARVGQHRLDQPSKGPLAVPSAKQTSTAMEVVLSVGEAALTAPWLLCSYKSGVSSPPPPMTQRQQFAAIKRRLVQKGQQIIRELIRARKAAKYAAFAARKKAAAVAAQKARAEAPRLAAQKAAIAKILRDRQLVSLPPPPPPSAARLAAEAELASKSASLQRLKAFHRANRVRPVLNNSFPSPPLACKPDPALLERLRLATPSRCTVATKRQRDFVVAPLATQIRVAKCASHQEAYDSCRSILIEEWPESRYLFGPLSFVGDWEHVPGMLMQYRLCVLFSMVRDVMPALSLVADTLHALRSGTAPNIVFKNAMSTANQILECSHSSHAAQGFGNFLSRGKSAAINLASGLSSFVGEKVVSGANHVVNKASEVIVDKLFVPFVKLLREHFDDTIGKWIPKLLGATQKIEELWRWSLEWAQNMSKKLDVSLRVLRGSALVGVGLLLVSGILYFAEQLLRSFGLLIVAGSFISMFVGGCLLAYAGSMAGIFDEQMMRVRGILCEIPMLLYLKAQPDPFFPKKSGGRAPTQGLTDVFGVPLSIMNAIGDGLVHHSLDTLTLMGKFGAAMDNVRKGITCMRSFVSWLMEHLALALDKITGKRTSFFRELATLINFDVEKWVRDSQQYLLAAEIYVDGDTVVMDTCRHLLDKGLKLQRMMVSAKSGCSFNYGRLVGDLVKRLSDLHKRYCASGRRVHYRLAPFWVYLYGGPRCGKSLFAQSFMNAAVDFMGTTVDNCYFKNARDDFWSGYRQEAICCVDDLSSCETQPSIESEFIQLITTMRYGLNMAGVEEKGASFDSKMVITTSNFFTAPTTAKIASKAAYNDRRHACILVQRKEGVAYNPSDPAAAAEAMFVDSTTQHPLSEWMSMQELSAELLLRYQQHREAQHAEYSYWKSTSRTSHDVFDILQKCVNGDTQWLSLPVDVIPPSIRQKHKGNRVFAIDGRIFMFDYMTLEYDEIKEKENLDARHLEARILEKYGDTRLLLEKWGANGVVAQFIEQLLEGPSNVASLEVLSKDSLESHKEFFSTLGLIERATLRAVQKKIDAAREDLMHLSGLKPGRSLTELFVEAYDWVYANGGKLLLVLAAVILILFFGSACIKLMQAIFCGAAGGTVSMAAVGKMTVQSTIPSGSYADVYNARNMTRVFRPQSVQGSSLAEAQFNESHAVNMLVRIDLPDGNIISACRFRGKSLALTKHQALTIPPGAKIHIVYTDNNGNTKAPLTHFFQPTGPNGEHFLRFFNGTEVCIYSHPQLSALPGAPQNYFLKDVEKISGDIAIKGCGIKLGRTSVGECVGVKDNEPVLNHWRAVAKVRTTKITIDNYSEGGDYSNDLPTSIISEYVNSPEDCGALLVAHLEGGYKIIGMHVAGSSYPVEVDGVQMPRYISHASFFPDYSSFAPCQSSVIKSLIQEAGVEERGVSKVGHIKDPAETPHVGGKTKLELVDEAFLVPSPVEVKIPSILSKDDPRIPEAYKGYDPLGDAMEKFYEPMLDLDEDVLESVMADMYDEFYDCQTTLRIMSDDEVINGSDFGFNIEAVVKGTSEGYPFVLSRRPGEKGKARFLEELEPQPGDTKPKYKLVVGTEVHSAMVAMEQQARTEVPLLIGMDVPKDERLKPSKVLEKPKTRTFVVLPMHYNLLLRKYVGILCSSMQVNRHRLACAVGTNPYSRDWTDIYQRLAEKNSVALNCDYSRFDGLLNYQAYVHIVNFINKLYNDEHSIVRGNLLMAMYGRWSVCGQRVFEVRAGMPSGCALTVIINSLFNEMLIRYVYRITVPRPLVNNFKQEVCLIVYGDDNLISIKPDTMKYFNGEQIKTILAKYKVTITDGSDKNSPVLRAKPLKQLDFLKRGFRVESDGRVLAPLDLQAIYSSLYYINPQGNILKSLFLNAQVALRELYLHGDVEQFTAVRNFYVNQIGGNFLSLPQWRHCASFHDEQYSQWKPWSPVKFLEVDVPDAKFLQHKAPATALSIVADRLAVAGPGWRNKDPDRYLLVSLTSLKANEGGLYFPVDYGEGTGQQATEASIRAYRRLKDHRVRHMRDSWNEGKTIVFRCEGPFVSGWAAAISFGTSVGMNAQDLLINYGIQGGAHKEYLGRYFVGARFKELERYDRPFQSRIIAS
What is the function of this protein?
The VPg-NTB polyprotein may act as a membrane-anchor for the replication complex.
What are the official names of this protein?
RNA1 polyprotein, P1.
What is the protein family that this protein belongs to?
Belongs to the nepoviruses RNA1 polyprotein family.
What are the subcellular locations of this protein?
[Viral genome-linked protein]: Host endoplasmic reticulum lumen. SUBCELLULAR LOCATION: [Putative ATP-dependent helicase]: Host endoplasmic reticulum membrane; Single-pass membrane protein. Note=The NTB-VPg polyprotein is associated with endoplasmic-derived membranes that are active in viral replication.
Protein: PPIA_NAEFO
Sequence: ENFKIKHTEPGLLSMANAGKN
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase, PPIase, Cyclophilin, NF008, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.
Protein: ACCA_ACAM1
Sequence: MAVSDRKLQLLDFEKPLAELEDRIEQIRSLSEQNGVDVTDQIAQLEGRAEQLRQEIFSSLTPMQELQLARHPRRPSTLDYIHAISDEWMELHGDRRGYDDPAIVGGVGRIGGQPVLMLGHQKGRDTKDNVARNFGMPFPSGYRKAMRLMDHADRFGLPIISFIDTPAAWAGLEAEQFGQGEAIALNLREMFRLDVPIICTVIGEGGSGGALGIGVGDRLLMFEHSIYSVAPPEACAAILWRDAQEGPQAAEALKITATDLQELGIIDQILPEPPGGAHVNPIKAANIIKTAILSNLEELWRLSPQERRQQRYHKFRNMGIFSQLP
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAP0_PONAB
Sequence: MESGSTAASEEARSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERLEKEEAKQIQNLQKAGTRTDSREDEISPPPPNPVVKGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQGETDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV
What is the function of this protein?
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.
What are the official names of this protein?
cAMP-dependent protein kinase type I-alpha regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the cAMP-dependent kinase regulatory chain family.
What are the subcellular locations of this protein?
Cell membrane.
Protein: KCC2D_XENLA
Sequence: MASTTCTRFTDEYQLFEELGKGAFSVVRRCIKINIGQEYAAKIINTKKLSARDHQKLEREAKICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKLKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRINATEALRHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHRFYFENALSKSNKPVHTIILNPHVHLIGEDAACIAYIRLTQYLDSAGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTIPN
What is the function of this protein?
CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system.
What are the official names of this protein?
Calcium/calmodulin-dependent protein kinase type II delta chain, CaM kinase II subunit delta, CaM-kinase II delta chain, CaMK-II subunit delta.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
Protein: SMR2_ARATH
Sequence: MSKLLETLEEEKTVEQKPRSQEEEDHQDSSKKEELLESLCTPTSSDHKIPEVETCPPPPRKRPREISLTKKTRLSKDLRFFEATDVGSQEVETLFVHEPNHVRKKRRSNSA
What is the function of this protein?
Cyclin-dependent protein kinase (CDK) inhibitor that restricts cell proliferation and cooperates with SIM and SMR1 to promote endoreplication during leaf development (PubMed:26546445).
What are the official names of this protein?
Cyclin-dependent protein kinase inhibitor SMR2, Protein SIAMESE-RELATED 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1490_MYCUA
Sequence: MTLPLLGPMTLSGFAHSWFFLFLLVVAGLIAIYVVLQLARQKRMLRFANMELLESVAPQRPSRYRHIPAMLLALSLVLFTVAMAGPTHDVRIPRNRAVVMLVIDVSQSMRATDVEPNRMVAAQEAAKQFADELTPGINLGLIAYAGTATVLVSPTTNREATKAALDKLQFADRTATGEAIFTALQAIATVGAVIGGGDTPPPARIVLFSDGKETMPTNPDNPKGAYTAARTAKDQGVPISTISFGTPYGFVEINDQRQPVPVDDETMKKVAQLSGGNSYNAATLAELNSVYVSLQQQIGYETIRGDASMGWLRLGALVLVAAALAALLINRRLPT
What are the official names of this protein?
UPF0353 protein MUL_1490.
What is the protein family that this protein belongs to?
Belongs to the UPF0353 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL22_PRUAP
Sequence: MISKAIIKKVSIAPRKARLVVDLIRGKEIKVAKAILMFTPKSASSIVLKLLNSAEANLAQNINLKSNDFYISEVYVNEG
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: FDHE_HAEIE
Sequence: MSIKILSESEIKQVANSYQAPAVLFANPKNLYQRRAKRLRDLAQNHPLSDYLLFAADIVESQLSTLEKNPLPPQQLEQLNAIEPLNAKTFKRDSIWREYLTEILDEIKPKANEQIAATIEFLEKTSSAELEEMANKLLAQEFNLVSSDKAVFIWAALSLYWLQAAQQIPHNSQVENAENLHHCPVCGSLPVASIVQIGTSQGLRYLHCNLCESEWNLVRAQCTNCNSHDKLEMWSLDEELALVRAETCGSCESYLKMMFQEKDPYVEPVADDLASIFLDIEMEEKGFARSGLNPFIFPAEEA
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE homolog.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_ALKEH
Sequence: MNRPLGIIGAGAWGTALAIAAGHAGHPVRLWGRDTAAVQAMARDRVNRRNLPDCPLPDPVQPQPDLTALVAECDDLLLVVPSRAFESMLHTLAPLIERRHRLGWATKGLDAASGGLLSQVVQRVLKPLPPLAVLSGPSFAAEVGRGLPTAVTVAATDQGFASDLADAFRYERFRVYTSTDLVGVQLGGAVKNVLAIATGVADGLGFGANARAALITRGLAETRRLSEALGADPDTLTGLAGMGDLILTCTDDQSRNRRLGLALGRGEDLDEAVEAIGTVEGVRTADELHRLATQAGVEMPICEQVHLRLAGRVSTREAVENLLLRPGGRQEQ
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBM38_XENLA
Sequence: MHTVQKDTTFTKIFVGGLPYHTTDASLRKYFEVFGDIDEAVVITDRQTAKSRGYGFVTMSDRAAAERACKDPNPIIDGRKANVNLAYLGAKPRNLQSAFTIGVQQLHPAFIQRPFGLTPQYIYPPTIVQPSMVIPTPIPSLQSPYIDYNAATQAYTHYTTAAYEQYPYAASPATGYMGYGYTSPVQQPLSTTTGAPPTAYIQYQPQQLQPDRMQ
What is the function of this protein?
RNA-binding protein that specifically bind the 3'-UTR of VegT transcripts, leading to maintain their stability and stimulate their translation, thereby playing a role in germ layer formation.  VegT is a localized maternal determinant essentially required for endoderm formation.  Also has some proneural function in the open neural plate and in the context of retinogenesis.  May also act as a mRNA splicing factor.  May play a role in myogenic differentiation.
What are the official names of this protein?
RNA-binding protein 38, RNA-binding motif protein 38, RNA-binding protein XSeb4R.
What is the protein family that this protein belongs to?
Belongs to the RBM38 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: RSMJ_ACIBS
Sequence: MEKNCGSGQSKLKALRMHIYFEVDFQEQAQHYQAVLHSRGVTVDLQPIEKLNARFLRLNPDLALCVDENGLWLSANGMKMQPDWKAEIPRLKRASLKSEMIARACQLGEKPVLVDATAGLGHDSLLMAYLGAQIQLVERHPILFTLLEDSKAQAQRDPFLSQFMDRIQLIFADSASYLKQLDQEEKTVDVVYLDPMFPQRDQNQQAIKKQAQVKKQMQLLHLLLPEDGEMDLGGHLLELAKKVAKRVIVKRPRHAIFLANQEPAHQWQGDACRFDAYFQ
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_OLEA2
Sequence: MVDILNLTFEELETFLVEKLGEKKFRARQIWQWLWNKYVRDFDQMTNVSKQTRAQLKEHARIFWPEVVTTSKSQDGTTKFLLRLADGALVETVLIPGSQGRITQCLSCQVGCAMGCTFCATGTLGFERNMTMSEILGQVLVAREYLNDVAERPILRNLVFMGMGEPLLNLDEIMRSLHTLNSELGLQFSPRRITVSTCGVNPEGLRRLGESGLAYLAVSLHAPTQELRRTIMPKAARWELNDFIEALQSYPLKTRERITFEYLLLGGVNDSLEHAKQLVRLVSRTKAKLNLIVYNPSGDEADPYAAPTEERILAFEQYLWSKHVTAIIRKSKGADIKAACGQLKAAETGGTPCCAQND
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIGA_STAA8
Sequence: MSDNTVKIKKQTIDPTLTLEDVKKQLIEKGKKEGHLSHEEIAEKLQNFDIDSDQMDDFFDQLNDNDISLVNEKDSSDTDEKLNPSDLSAPPGVKINDPVRMYLKEIGRVNLLSAQEEIELAKRIEQGDEVAKSRLAEANLRLVVSIAKRYVGRGMLFLDLIQEGNMGLIKAVEKFDFNKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINKLIRVQRQLLQDLGRDPAPEEIGEEMDLPAEKVREILKIAQEPVSLETPIGEEDDSHLGDFIEDQEAQSPSDHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVGKVFGVTRERIRQIEAKALRKLRHPSRSKRLKDFMD
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is the primary sigma factor during exponential growth.
What are the official names of this protein?
RNA polymerase sigma factor SigA.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YSCR_YERPE
Sequence: MIQLPDEINLIIVLSLLTLLPLISVMATSFVKFAVVFSLLRNALGVQQIPPNMAMYGLAIILSLYVMAPVGFATQDYLQANEVSLTNIESVEKFFDEGLAPYRMFLKQHIQAQEYSFFVDSTKQLWPKQYADRLESDSLFILLPAFTVSELTRAFEIGFLIYLPFIVIDLVISNILLAMGMMMVSPMTISLPFKLLLFVLLDGWTRLTHGLVISYGG
What is the function of this protein?
Component of the yop secretion machinery.  May have a role in the negative pathway regulation of yop expression controlled by calcium.
What are the official names of this protein?
Yop proteins translocation protein R.
What is the protein family that this protein belongs to?
Belongs to the FliP/MopC/SpaP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UREF_POLSJ
Sequence: MPASPAAQLPAASLLQLIWLASPALPVGGFSYSEGLETAVERAGVTTEVLAGDWLRDQLHLSLARGDLAVIAQAIPAWRVGDVQRIRELNDWVLQTRETSEMRAQAEQMGRSLLDWLRNHDGANAQHITACAQMQPTYPVAFALAASQTAAGVRDCLLAYAFGWAENAMQAALKSVPLGQSAGQRMLARLASDIPTAVEAAISLPDDERQAFSPMLAILSSQHETQYSRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HXB3_CHICK
Sequence: MQKTTYYESSTLFGGYSYGSTNGFGYEGPQQPFQPGSHVENDFQRSACSLQSLGNTTQHAKSKDLNGSCMRPSLPQEHHPPPTVSPPPNPTTNSTSSNSIPSGSAKVPRVKPTSVQTPSLTKQIFPWMKESRQNSKQKSSSPSTETCSGEKTPPGSSASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKSKGMGSSSGGPSPTGSPPQPMQSSAGFMNALHTMSSNYDAPSPPSLNKPHQNAYAHVTNYQNPIKGALQQKYTNTAPEYDPHVLQGNGVAYGTPSMQGSPVYVGGNYVDSLPTSGPSLYGLNHLPHHQAANMDYSGPPQMPPSQHHGPCEPHPTYTDLWPAQPTHLLGGQNPGGPKLTHL
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-B3, Homeobox protein Hox-2.7, Chox-2.7.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.