PharMolix/UniProtQA huggingface dataset:
Protein: RPPH_HELPJ
Sequence: MLHKKYRPNVAAIIMSPDYPNTCEVFIAERIDIEGAWQFPQGGIDEGETPLEALYRELLEEIGTNEIEILAQYPRWIAYDFPSNMEHKFYSFDGQKQRYFLVRLKHVNNIDLNKHTPEFRSYQFIQLKDLLKKIVPFKRQVYRQVIAYFRKEGYLGC
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: MHPB_AZOSB
Sequence: MSAMLQCMSHTPLKGYFDPAADVVEEVAALAAAVREEVAHFDPEVVYLFAPDHYNGFFLDLMPQFCLGIEATSVGDYQTPKGPLRVPRALAEACAGAVIARGIDLAFSYRMQVDHGFAQTLVEVLGGLARYPVVPIMINAVAPPLASFQRARLLGAAVGEFARGQGGRALFIASGGMSHNPPIPQIATATDPEVIERIVAGRNPTPEARAARQQRTVAAAQAFAAGDSPLRPLNPDWDRALMKRLCSRDWAAIDAYRNDEVSAAAGASAHELKSWVAATAAMESATAGQWDARERYYRAIPEWLAGFGAMSGLGRHP
What is the function of this protein?
Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6-ketononatrienedioate, respectively.
What are the official names of this protein?
2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase, 3-carboxyethylcatechol 2,3-dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the LigB/MhpB extradiol dioxygenase family.
Protein: MUTS2_GEMAT
Sequence: MNAHALGILEFSRLLAHVAGRATSAPGAAAVRALTPRTDREWIEAEHARVRAVRALVASELGWPTEPIPDIGEPLRRLRIEGLSWTALELLQGATLLRSSRRTRATLRDPRRPAIMLAYLVRYAEALVDLEPREQAIERAIGDDGTVRDDASPTLRKVRRDLRETEGQLVRLLEREMGKLEAHHQVSDLSVTMRNGRWVMPMRREARGYVGGIVHDSSGTGATIYVEPPAAVEFGNRVRELEIEEQREVERVLRALTDEIRPYHDAIGGAYDALVALDSLYARARYAIEAQCAPVTFGEPSAGFRIVDGRHPLLLASGGAVVPFDLTLHAGERTMLVSGPNTGGKTVLLKAIGLISMMAQCGVPAPLGETSQLAVFDDLYADVGDEQSIEASLSTFSAHLKNLGEILRSATTSSLVLIDELGSGTDPAEGAALGGAILETLTRRGTLTLATTHLGQLKLLATDVEGVVNASLQFDAVQLAPTYRLLKGVPGRSYGLSIARRLQIDEAVIQRAEERLPSGERDMAVLLADVEAREALLADRERLMEIDQEKLRARLATVGDRELKVREREREAERSARQEARRFLLEARGQVERAIADVKRQAQVEGEAFEETARAARRSIEEAAAEQGEAVAYVGLRGERDRARVDAKRGAAAAAANPSLGRTLRPERGAVAPLGEGDHVIVSTLDGKQGRIVSVRGQDARVAVGSLTVTVPLRTLTRSAAAPVSMYRTPILGDVPEVEPVREVDVRGLRVDEVDDQVLQALDAAVRNDLRELRIIHGKGTGALRSRVSEMLKKDTRVTGFRLGAWNEGGAGVTVAELA
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: NDK1_SACOF
Sequence: MESTFIMIKPDGVQRGLIGEIISRFEKKGFYLKALKLVNVERSFAEKHYADLSSKPFFQGLVDYIISGPVVAMVWEGKSVVTTGRKIIGATNPLVSEPGTIRGDFAVDIGRNVIHGSDSIESANKEIALWFPEGLADWQSSQHPWIYEK
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.  Also exhibits a kinase-like activity towards histone H1.
What are the official names of this protein?
Nucleoside diphosphate kinase 1, Nucleoside diphosphate kinase I, NDK I, NDP kinase I, NDPK I, PP18.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
Protein: MYOG_CHICK
Sequence: MELFETNPYFFPEQRFYDGENFLGSRLQGYEAAAFPERPEVTLCPESRGALEEKDSTLPEHCPGQCLPWACKICKRKTVSIDRRRAATLREKRRLKKVNEAFEALKRSTLLNPNQRLPKVEILRSAIQYIERLQSLLSSLNQQEREQRELRYRPAAPQPAAPSECGSGSSSCSPEWSTQLEFGTNPADHLLSDDQAEDRNLHSLSSIVESIAVEDVAVTFPEERVQN
What is the function of this protein?
Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.  Induces fibroblasts to differentiate into myoblasts.  Probable sequence specific DNA-binding protein (By similarity).
What are the official names of this protein?
Myogenin, Myogenic factor.
What are the subcellular locations of this protein?
Nucleus.
Protein: KGSD1_AZOBR
Sequence: MANVTYTDTQLLIDGEWVDAASGKTIDVVNPATGKPIGRVAHAGIADLDRALAAAQSGFEAWRKVPAHERAATMRKAAALVRERADAIAQLMTQEQGKPLTEARVEVLSAADIIEWFADEGRRVYGRIVPPRNLGAQQTVVKEPVGPVAAFTPWNFPVNQVVRKLSAALATGCSFLVKAPEETPASPAALLRAFVDAGVPAGVIGLVYGDPAEISSYLIPHPVIRKVTFTGSTPVGKQLASLAGLHMKRATMELGGHAPVIVAEDADVALAVKAAGGAKFRNAGQVCISPTRFLVHNSIRDEFTRALVKHAEGLKVGNGLEEGTTLGALANPRRLTAMASVIDNARKVGASIETGGERIGSEGNFFAPTVIANVPLDADVFNNEPFGPVAAIRGFDKLEEAIAEANRLPFGLAGYAFTRSFANVHLLTQRLEVGMLWINQPATPWPEMPFGGVKDSGYGSEGGPEALEPYLVTKSVTVMAV
What is the function of this protein?
Catalyzes the NAD(P)(+)-dependent oxidation of alpha-ketoglutaric semialdehyde (alphaKGSA) to alpha-ketoglutarate.  Is involved in a degradation pathway of L-arabinose that allows A. brasilense to grow on L-arabinose as a sole carbon source.  Prefers NAD(+) to NADP(+) as a cosubstrate.  Displays broad substrate specificity: exhibits the highest activity with alphaKGSA and succinic semialdehyde as substrates, but to a lesser extent, is also active with glutaraldehyde, benzaldehyde, and a number of aldehydes from C3 to C8.
What are the official names of this protein?
Alpha-ketoglutaric semialdehyde dehydrogenase 1, alphaKGSA dehydrogenase 1, 2,5-dioxovalerate dehydrogenase 1, 2-oxoglutarate semialdehyde dehydrogenase 1, KGSADH-I, Succinate-semialdehyde dehydrogenase [NAD(+)], SSDH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: EFTS_LEGPA
Sequence: MSTISAALVMQLRERTGAGMMECKKFLIATNGDIEQAIIEMRKAGQAKADKKADRVAAEGIIVIARSSDERTAVMLEINSETDFVARDENFTNFANAVADAALTNLPKNIEDLSNQALSSGTTVEQARQELVAKIGENIKLRRLERMHCDGVIGYYLHGSRIGVMVALKNGSEALAKDIAMHVAASKPMVVSRDQVPAEAIENEREIFTAQAKESGKPQEIIDKMIDGRINKFIDEVSLLGQPYVKDPNIKVGQLLKEKNAEVISFVRYEVGEGIEKKEDNFVEEVMAQVRT
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSTX1_TOBAC
Sequence: MAEVKLLGFWYSPFSRRVEWALKIKGVKYEYIEEDRDNKSSLLLQSNPIHKKVPVLIHNGKRIVESMVILEYIDETFEGPSILPKDPYDRALARFWAKFLDDKVPAVVKTFLRKGEEQEKDKEEVCEMLKVLDNELKDKKFFVGDKFGFADIAANLVAFWLGVFEEASGVVLVTSEKFPNFCKWRGEYINCSQIKESLPPRDELLAFYRSRCQAAAASASAPK
What are the official names of this protein?
Probable glutathione S-transferase, Auxin-induced protein PGNT1/PCNT110.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. HSP26 family.
Protein: RL11_STRP6
Sequence: MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNARTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNTTKVATVTRAQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: PSAM_EMIHU
Sequence: MITDSQIFFALCIALTAAVLAIGLGRQLYV
What are the official names of this protein?
Photosystem I reaction center subunit XII, PSI-M.
What is the protein family that this protein belongs to?
Belongs to the PsaM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GPC3_DANRE
Sequence: MMPGLKLYGALILCVLVLPFSRPSSQVLDCREVRSSFQFLYPGMKWTPETPVSGSDLQVCQPKGLTCCSRKMEERYLLIAKQNMESSLQATSAQLKGLIIQNAALFQEAFDMVLRLGRNSTLMVLREEFPGLGAGASGAVTQLFLDMSLYILGSDANVNDMVSTFFSRLFPLTYRRLLGNGAVAGISEECLRGAWKGSSAYGSFPKMMMTRLSRSLLATRVFLQALNLGIEVVNTTQHLRAGRDCGRSLLKLWYCPHCQSLLEARPCRPLCVSTMGACLGGTTEVQPHWRAYVDELGSLAAAMKGEQDIEAVVLRLHVIIRQALKQAVASKSKVSAQVSGMCVHAPPRVSRAVPVSAEHTSASTVNHNRPPMNFDPDETLFGRRREFISGLRGFSQFYSGLGEALCSKEPTSLNSSLCWNGQEMTDKFPGPGLKRVHPHGSESKQKTPEPVISQIIDKLKHINQLLRMVTLPEKRWRARQGGGGARRNPSGPGQTDEDEEGLESGDCDDEDECTGVSGLGPPPRRKRLRIFADLADNLAIDDLTLHELLLTPRLATDAHGGSSIPGAAHVPTAAFIFTITIIIFITLGLQ
What is the function of this protein?
Cell surface proteoglycan (By similarity).  Negatively regulates the hedgehog signaling pathway (By similarity).  Positively regulates the canonical and non-canonical Wnt signaling pathways (By similarity).  Binds to CD81 which decreases the availability of free CD81 for binding to the transcriptional repressor HHEX, resulting in nuclear translocation of HHEX and transcriptional repression (By similarity).  Inhibits the dipeptidyl peptidase activity of DPP4 (By similarity).  Plays a role in limb patterning and skeletal development (By similarity).  Modulates the effects of growth factors on renal branching morphogenesis (By similarity).  Required for coronary vascular development (By similarity).  Plays a role in regulating cell movements during gastrulation (PubMed:14610063).
What are the official names of this protein?
Glypican-3.
What is the protein family that this protein belongs to?
Belongs to the glypican family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.
Protein: SCX2_CENSU
Sequence: KEGYLVSKSTGCKYECLKLGDNDYCLRECKQQYGKSSGGYCYAFACWCTHLYEQAVVWPLPNKTCN
What is the function of this protein?
Beta toxin that binds site-4 of sodium channels (Nav) and reduces peak current (observed on Nav1. 6/SCN8A (IC(50)=307 nM)), shifts the voltage of activation toward more negative potentials (observed on Nav1. 6, Nav1. 1 (weak), Nav1. 2 (weak), and Nav1. 7 (weak)), and induces resurgent currents at negative voltages following brief and strong depolarizations (observed on Nav1. 6, Nav1. 1 (weak), and Nav1. 7 (weak)) (PubMed:22200496).  A reduction of peak current of Nav1. 5/SCN7A has been observed in another study (IC(50)=35-40 nM) (PubMed:22251893).  This toxin is only active on mammals (PubMed:17544584).  It has been shown to bind phospholipids (PubMed:15632158).
What are the official names of this protein?
Beta-mammal toxin Css2, Css II, CssII.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MRNIP_BOVIN
Sequence: MAPPQQARVLRCCCCSLFQAHQVKKSLKWTCKACGKKQSFLQAYGEGSGADCRRHVQKLNLLQGQISEMSLRSLGESISANEEENVGPWQAARASPQETLQPSKNRWLKYLERDSKELGLKGGGVCFNSQPSSETEKPDPPFSTGLPRKRKWNQSTVQPLCGPHVQDSRNCEVTLKSLKARPLHPTWGARSSPDCSTWDLPCISEELPPSFTQDRAGLAGKGRESSREDLDTMELVPRGEPPCPAQQVRTMSKWEQCLGNSSHLDTEPLTPLQRGLRPIQAAQAEQGAPRAQTPREGGLCRLPGARQSPQTTHTPMPGPKWLCGRIPEQSQGTGPWAEGVPLVKGMQARSSLMRLCDLFKTGEDFDDDL
What is the function of this protein?
Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex.  Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair.
What are the official names of this protein?
MRN complex-interacting protein, MRN-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the MRNIP family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Note=Recruited to sites of DNA damage. Phosphorylation on Ser-115 induces its nuclear localization and promotes genome stability.
Protein: ADHS_METVS
Sequence: MKMFDNIKNVGKLIRLERIFDKKSEKTVIIPMDHGVSSGPLEGIKDMRIATNAVADGGANAVLGHKGLVRHGHRGYGRDIGLIVHMSAGTSISPDPNKKVIVTTVEDALRMGADAVSLHVNVGAETDFEMYRDLGLISETCEYWGMPLIAMMYPRGPKIKDERDPEVVAHAARLGAELGADIIKTNYTGDIDSFKDVVKGCPAPIVIAGGPKTNTDEEFLQMVKDAMHAGSAGVASGRNVFQHKDVRGITSAICKIVHEDVEVKEALNEIKI
What is the function of this protein?
Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH).  Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
What are the official names of this protein?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase, ADH synthase, ADHS, ADTH synthase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
Protein: YBHG_ECOL5
Sequence: MKKPVVIGLAVVVLAAVVAGGYWWYQSRQDNGLTLYGNVDIRTVNLSFRVGGRVESLAVDEGDAIKAGQVLGELDHKPYEIALMQAKAGVSVAQAQYDLMLAGYRDEEIAQAAAAVKQAQAAYDYAQNFYNRQQGLWKSRTISANDLENARSSRDQAQATLKSAQDKLRQYRSGNREQDIAQAKASLEQAQAQLAQAELNLQDSTLVAPSDGTLLTRAVEPGTVLNEGGTVFTVSLTRPVWVRAYVDERNLDQAQPGRKVLLYTDGRPNKPYHGQIGFVSPTAEFTPKTVETPDLRTDLVYRLRIVVTDADDALRQGMPVTVQFGDEAGHE
What are the official names of this protein?
UPF0194 membrane protein YbhG.
What is the protein family that this protein belongs to?
Belongs to the UPF0194 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: G3P1_AGABI
Sequence: MVNVGINGFGRIGRLVLRNALQMQILTVVAVNDPFLDVEYMAYLFKYDSVHGRYQGKVETKDGKLIIDGHKIAAFAEREPANIKWADCGAEYIVESTGVFKTEELAKEHLKGGAKKVVITAPGSGVPTYVVGVNLDKYDPKEVVISNASCTTNCLAVLAKVINDKFGIVEGLMTTVHATTATQKTVDAPAKKDWRSGRSVTNNIIPASTGAAKAVTKAIPDLEGKLTGLAFRVPTLDVSVVDLVVRLEKETSYDDVKKAMRDAADGKHPGIEKGIVDYTEEDVVSTDFVGSNYSMIFDAKAGIALNSRFMKLVAWYDNEWGYARRVCDEVVYVAKKN
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase 1, GAPDH 1.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTMR8_CHICK
Sequence: MEHITTPKVENVKLLDRYTNRKAASGTLYLTATHLIYVDASAEVRKETWILHHHIATVEKLPLTTAGCPLLIHCKNFHVAHFVIGQERDCHEVYTSLLKLSQPVKPEELYAFSYNPKMSKDNREIGWKLIDLKVDYQRMGIPNDYWEITDLNKDYEVCNTYPPEIVVPRAASKATVIGSSRFRSRGRIPVLSYLYKENNAAICRCSQPLSGFSARCLEDEQMLQAIREANPGSPFMYVVDTRPKLNAMANRAAGKGYENEDNYDNIRFKFIGIENIHVMRSSLQKLLEVCETKSPSMSDFLTGLENSGWLRHIKAVMDASVFLAKAVKDEKASVLVHCSDGWDRTAQVCSLASLLLDPFYRAFKGFMVLIEKEWIAMGHKFSHRCGHLDGDPKEVSPVFTQFIECVWQLMQQFPCTFEFNEHFLLEIHDHVYSCQFGNFLGTCHKEREDLKIFEKTHSLWPFLLQKKQELRNPLYRGFTAYKELQPNTLPFSFQFWCGMYNRFDKGMHPKQCVLDHLLSCMNQKIKLEDNASELENKLPFLDGPLPNEACFLSKVGCAASKTPMLNTPQDYEGEAPPVLTNGISVGDINVTSDVDQRNKENLANHRDLHLNDSVDVLNSEAKDGKPQHH
What is the function of this protein?
Phosphatase that acts on lipids with a phosphoinositol headgroup (By similarity).  Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate (By similarity).
What are the official names of this protein?
Myotubularin-related protein 8, Phosphatidylinositol-3,5-bisphosphate 3-phosphatase, Phosphatidylinositol-3-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
What are the subcellular locations of this protein?
Nucleus envelope.
Protein: P2C06_ARATH
Sequence: MGLCHSKIDKTTRKETGATSTATTTVERQSSGRLRRPRDLYSGGEISEIQQVVGRLVGNGSSEIACLYTQQGKKGTNQDAMLVWENFCSRSDTVLCGVFDGHGPFGHMVSKRVRDMLPFTLSTQLKTTSGTEQSSSKNGLNSAPTCVDEEQWCELQLCEKDEKLFPEMYLPLKRALLKTCQQMDKELKMHPTINCFCSGTTSVTVIKQGKDLVVGNIGDSRAVLATRDQDNALVAVQLTIDLKPDLPSESARIHRCKGRVFALQDEPEVARVWLPNSDSPGLAMARAFGDFCLKDYGLISVPDINYHRLTERDQYIILATDGVWDVLSNKEAVDIVASAPSRDTAARAVVDTAVRAWRLKYPTSKNDDCAVVCLFLEDTSAGGTVEVSETVNHSHEESTESVTITSSKDADKKEEASTETNETVPVWEIKEEKTPESCRIESKKTTLAECISVKDDEEWSALEGLTRVNSLLSIPRFFSGELRSSSWRKWL
What are the official names of this protein?
Probable protein phosphatase 2C 6, AtPP2C06.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: NS7B_CVCAI
Sequence: MKFVILVLCLSFVNGYGIKRNVQEHDLKDSHEHPTMTWELLEKFVGNTLYITTPQVLALPLGAQIYCDEIEGFQCSWPGYKNYAHDHTDFHFNPSNPFYSFVDTFYVSLGDSADKIYLRVISATSREKMLNIGCHTSFSVNLPIGTQIYHDKDMKLLVEGRHLECAHRIYFVKYCPYHTHGYCFDDKLKVYDLKRVKSRKDFEKISQYQKSEL
What are the official names of this protein?
Non-structural protein 7b, ns7b, Accessory protein 7b.
Protein: DER_SHEAM
Sequence: MIPVVALVGRPNVGKSTLFNRLTRTRDALVADYPGLTRDRKYGRAHLSGYEFIVVDTGGIDGTEEGIETKMAEQSLAAIEEADVVLFMTDARAGLTAADLAIAQHLRSRDKITFVVANKVDGIDADSACGEFWQLGLGEVYQMAAAQGRGVTGLVEYALAPFAEAMGLVRDDDGEVVTDERNYTEEEAEAEQQRLAEQPIKLAIIGKPNVGKSTLTNRILGEERVVVYDQPGTTRDSVYIPMERDGRNYVLIDTAGVRRRARVHEVIEKFSVIKTLKAVEDSNVVLLVIDAHEGIAEQDLGLLGFVLNSGRALVLAVNKWDGLDQDVKDRVKTELDRRLGFIDFARIHFISALHGTGVGHLFESIEEAYDSATRRVSTSMLTRIMQMAQDDHQPPMVNGRRVKLKYAHVGGYNPPIVVVHGNQVSRLPDSYKRYMMNYYRRALKVVGTPIQLRFHEGDNPFEGRKEKLTLSQERRRKRMMSHIKSKKA
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: PHLD_ARATH
Sequence: MTLASDFGFPSAISSSFTILEERYHNNFPNTLCVSSGQESMNNNPVPCQVFPLVSGGSSGGNLFSSSSGFCNGVYVSSSSQARPSVSTVPRDRITVAHVSGEGQRQECPVETHSLQLINQPQEQKIMTWSSDQIRGFFDFPVPDPQAASSRTMVSSKEVLSKCEWPDWADQLISDDSLEPNWSELLGDPNVLNLYSKIETQSSDIARQEIVFRNQHQVDPSMEPFNAKSPPASSMTSKQRMRWTPELHEAFVEAINQLGGSERATPKAVLKLINSPGLTVYHVKSHLQKYRTARYKPELSKDTEEPLVKNLKTIEDIKSLDLKTSIEITEALRLQMKVQKQLHEQLEIQRSLQLQIEEQGRYLQMMIEKQQKMQENKKDSTSSSSMPEADPSAPSPNLSQPFLHKATNSEPSITQKLQNGSSTMDQSESTSGTSNRKRVRED
What are the official names of this protein?
Myb family transcription factor PHL13, Protein PHR1-LIKE 13.
What is the protein family that this protein belongs to?
Belongs to the MYB-CC family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RBFA_ALBFT
Sequence: MRKKSKTPNRAFKVADQIQRDLTELIARELKDPRVGMVTIQAVEVTPDYAHAKVYFSLLAGDPKACTEGLNQAAGFLRAGLFKRLHIHTVPTLHFLFDQTTERAADMNALIARAVASRAKED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBA4A_HUMAN
Sequence: MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGKHVPRAVFVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLDRIRKLSDQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGIDSYEDEDEGEE
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha-4A chain, Alpha-tubulin 1, Testis-specific alpha-tubulin, Tubulin H2-alpha, Tubulin alpha-1 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PNP_RICCK
Sequence: MFNEITKSVTWNGKVLELSTGKIARQADGSVTVKMGNSVLLCTAVVANTAKEGIGFFPLTINYREMAYAVGKIPGGFFKREGKASEREVLVSRLIDRPIRPLFHPAFVNETHVTCTVLSYDPETPVDILAIIGASAALALSPAPYLEIVAASKVGLINGEFVLNPTLELLKTSQLDLVVAGTTESVMMVESEAHLLSEAQMLEAVKFGFESFQPVVKIIKELAEEAKRPKLEMQDLYPSVLKNEIEQLFAKEIEQAFAIKSKQERSTSLDLISEKVITHFISNIENKKYNNYQIESALKSVESDILRKEILEKNKRIDGRSTMDIRQIACEVGLLPSAHGSALFTRGETQSLVSSTLGTSLDEQIVDNLEGEYKERFMLNYIFPPYSVNEAMPMKAPSRREVGHGKLAWRAINPILPNKVQFPYSIRVVAETTESNGSSSMATVCGSSLALMQTGIPIKAPVAGIAMGLVKEGKKFAVLSDILGDEDYFGDMDFKVAGTSEGITALQMDIKISGVDFKIMKVALEQARLGRLHILEQMNKVISKPNSELSKNAPSTTTIKIDKDKIRDIIGPGGKIIKEICETSGAKIDISDDGTVSVYAADRDKLKIASDKIKAIAIEPEIGEIFNGTVTKILDSGAFINYLGNKDGFVHISEISEERIDTVSSVIKQGDIVKVKLIGFDNKGKAKLTIKNADKDKSLNNPKPQNSINNAKENSEHVRCDSIKKRAWNEDNNAETAEFITERKYFN
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXK_SHIB3
Sequence: MSSLLLFNDKSRALQADIVAVQSQVVYGSVGNSIAVPAIKQNGLNVFAVPTVLLSNTPHYDTFYGGAIPDEWFSGYLRALQEHDALRQLRAVTTGYMGTASQIKILAEWLTALRKDHPDLLIMVDPVIGDIDSGIYVKPDLPEAYRQYLLPLAQGITPNIFELEILTGKNCRDLDSAIAAAKSLLSDTLKWVVITSASGNEENQEMQVVVVSADSVNVISHSRVKTDLKGTGDLFCAQLISGLLKGKALNDAVHRAGLRVLEVMRYTQQHESDELILPPLAEA
What is the function of this protein?
B6-vitamer kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxine (PN), pyridoxal (PL), and pyridoxamine (PM), forming their respective 5'-phosphorylated esters, i. e.  PNP, PLP and PMP.
What are the official names of this protein?
Pyridoxine/pyridoxal/pyridoxamine kinase, PN/PL/PM kinase, B6-vitamer kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxK subfamily.
Protein: MGN_DANRE
Sequence: MSTSDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDVMIRKEAYVHKSVMEELKRIIDDSEITKEDDALWPPPDRVGRQELEIVIGDEHISFTTSKIGSLIDVNQSKDPEGLRVFYYLVQDLKCLVFSLIGLHFKIKPI
What is the function of this protein?
Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.  The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism.  The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs throughout all stages of mRNA metabolism thereby influencing downstream processes including nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD) (By similarity).
What are the official names of this protein?
Protein mago nashi homolog.
What is the protein family that this protein belongs to?
Belongs to the mago nashi family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm. Note=Travels to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA.
Protein: PETL_SOLBU
Sequence: MLTITSYFGFLLAALTITSALFIGLSKIRLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.