PharMolix/UniProtQA huggingface dataset:
Protein: RL4_PROA2
Sequence: MELKVINTAGAETGEVISLDDKVFAAKVSEHAVYLDVKSLLANKRQGTHKVKNRSEVRGGGKKPYRQKGTGHARQGSSRSGLMSGGGSIFGPQPHGYDLKVNRKIKRLARRSALSSKAGEGRIIVIEDFTFEQIKTRQFADILKNLGLDQKKTLVLLPEHNEIINRSGRNIPVLNIRVADQASTYDILDCQTVVMQKAAVKKIEETLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: NU4M_BALMU
Sequence: MLKFIIPTIMLMPLTWLSKNNLIWINSTAHSLLISFSSLLLLNQLNDNSLNYSLIFFSDPLSTPLLMLTMWLLPLMLMASQSHLIKEPPVRKKLYITMLIMLQALLIMTFTATELILFYIMFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLIGSLPLLVALVYLQNTTGSLNFLLLQHWAKPLSASWSNIFMWLACMMAFLVKMPLYGLHLWLPKAHVEAPIAGSMVLAAVLLKLGGYGMLRITSMLNPLTEHMAYPFLMLSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVIAAILIQTPWSYMGATALMIAHGLTSSMLFCLANSNYERIHSRTMILARGLQVLLPLMATWWLLASLTNLALPPTINLVGELLVVMSVFSWSNPTILLMGANIVITALYTLYMLIMTQRGKHTHHINNIIPSFTREHALMALHIIPLLLLSLNPKIILGPLY
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: VP201_ARATH
Sequence: MGNLFVKKPQITEVDRAILSLKTQRRKLGQYQQKLEKVIEAEKQAARDLIREKRKDRALLALRKKRTQEELLKQVDQWVINVEQQLTDIELTSKQKAVFESLKQGNSAIKAIQSELDLDDVQKLMDDTADAKAYQDELNAILGEKLSAEDEEDILAEFDNLESQLIVDEMPEVPTKESEESEKLDLPDVPTKTPVASNAEITPAESATKTKVLEEPLPA
What is the function of this protein?
Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.  The ESCRT-III complex is probably involved in the concentration of MVB cargo (By similarity).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 20 homolog 1, AtVPS20-1, Charged multivesicular body protein 6 homolog 1, ESCRT-III complex subunit VPS20 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Endosome.
Protein: Y901_BACLD
Sequence: MAKYSSKINKIRTFALSLVFIGFIIMYVGVFFRSSVLLMSVFMILGVLSILLSTAVYFWIGMLSTKAVQVVCPNCEKPTKILGRVDMCMHCREPLTLDKNLEGKEFNESYNRKSQ
What are the official names of this protein?
UPF0295 protein BLi00901/BL05075.
What is the protein family that this protein belongs to?
Belongs to the UPF0295 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CHAC1_HUMAN
Sequence: MKQESAAPNTPPTSQSPTPSAQFPRNDGDPQALWIFGYGSLVWRPDFAYSDSRVGFVRGYSRRFWQGDTFHRGSDKMPGRVVTLLEDHEGCTWGVAYQVQGEQVSKALKYLNVREAVLGGYDTKEVTFYPQDAPDQPLKALAYVATPQNPGYLGPAPEEAIATQILACRGFSGHNLEYLLRLADFMQLCGPQAQDEHLAAIVDAVGTMLPCFCPTEQALALV
What is the function of this protein?
Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide.  Acts specifically on glutathione, but not on other gamma-glutamyl peptides (PubMed:27913623).  Glutathione depletion is an important factor for apoptosis initiation and execution.  Acts as a pro-apoptotic component of the unfolded protein response pathway by mediating the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade (PubMed:19109178).  Negative regulator of Notch signaling pathway involved in embryonic neurogenesis: acts by inhibiting Notch cleavage by furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in embryos (PubMed:22445366).
What are the official names of this protein?
Glutathione-specific gamma-glutamylcyclotransferase 1, Gamma-GCG 1, Blocks Notch protein, Botch, Cation transport regulator-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Golgi apparatus, trans-Golgi network.
Protein: GRAP_HUMAN
Sequence: MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPWYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFLWEEKFNSLNELVDFYRTTTIAKKRQIFLRDEEPLLKSPGACFAQAQFDFSAQDPSQLSFRRGDIIEVLERPDPHWWRGRSCGRVGFFPRSYVQPVHL
What is the function of this protein?
Couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.  Plays a role in the inner ear and in hearing (PubMed:30610177).
What are the official names of this protein?
GRB2-related adapter protein.
What is the protein family that this protein belongs to?
Belongs to the GRB2/sem-5/DRK family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Synapse. Note=Localizes at the presynaptic terminal.
Protein: MUTL_PELTS
Sequence: MANIIILDEFTAGQIAAGEVVERPVSVVKELVENSIDAGAGRIVVELEGGGLQAISVLDDGCGMSEEDLVLAFQRHATSKIKCSDDLNRITTLGFRGEALPSIAAVSKITVATRTRDALAGTRAEFAGGELIGKGPIGCPPGTSITVRDLFYNTPARRKAMKAPSAEGALCGGLISRLALARPEICFEVGIKGRRVFYSPGSGNLIDSLAAVYGRQIAAEMIAVKAVAEGLSINGYLGKPSLSRSTRSHITVIINGRYVRCPAIAEAIEGAYGTLLSRGRRPVAVLSLSVSPELLDVNIHPAKLEVRLLEEEKTASLLAGILKDALADKAVIPSAGNFRQAALRLENNKPGAEIFDGLGAGIIKTPGGGSSDRHVPGDKKNIQECLTLPDAHEYVADRVWVREAEDTPAYGNKVEKLPVLNALAHFPPVYILAGGEDGLYIVDQHAAHERIIYEEILSSGRTRPSQYLLVPVMLELDYREASILIERIIWFTDAGFVIEHFGGNTFLLRGVPFELPAGQEREIILDLLDYFESKGTGAGMTDFFKWAAASIACRSAVRAGEKLSLPSMNALLQRLSGTASPYTCPHGRPVVIKLSFRELELRFRR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: HEPC_HUMAN
Sequence: MALSSQIWAACLLLLLLLASLTSGSVFPQQTGQLAELQPQDRAGARASWMPMFQRRRRRDTHFPICIFCCGCCHRSKCGMCCKT
What is the function of this protein?
Has strong antimicrobial activity against E. coli ML35P N. cinerea and weaker against S. epidermidis, S. aureus and group b streptococcus bacteria.  Active against the fungus C. albicans.  No activity against P. aeruginosa (PubMed:11113131, PubMed:11034317).
What are the official names of this protein?
Hepcidin, Liver-expressed antimicrobial peptide 1, LEAP-1, Putative liver tumor regressor, PLTR.
What is the protein family that this protein belongs to?
Belongs to the hepcidin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PRRB_PRB02
Sequence: MGKLLLILGSAIALPSFAAAGGDLDISDTVGVSFWLVTAGMLAATVFFFVERDQVSAKWKTSLTVSGLITGIAFWHYLYMRGVWIDTGDTPTVFRYIDWLLTVPLQVVEFYLILAACTSVAASLFKKLLAGSLVMLGAGFAGEAGLAPVLPAFIIGMAGWLYMIYELYMGEGKAAVSTASPAVNSAYNAMMMIIVVGWAIYPAGYAAGYLMGGEGVYASNLNLIYNLADFVNKILFGLIIWNVAVKESSNA
What is the function of this protein?
Light-driven proton pump.  May have a regulatory rather than energy harvesting function, based on light-induced opening of proton channels, to modulate cell physiology depending on light intensity variations.  Could be, therefore, a sensory rhodopsin, potentially associated with a transducer component.
What are the official names of this protein?
Blue-light absorbing proteorhodopsin, BPR.
What is the protein family that this protein belongs to?
Belongs to the archaeal/bacterial/fungal opsin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MSRB_CLOPS
Sequence: MKYKKKEKEELKKILTEEEYYVTQENGTERPFTNEYWDFNGEGIYVDITTGEPLFTSKDKFHSSCGWPAFSKPIDRSIIKEKVDKSHGMVRTEVRSKLGDSHLGHVFCDGPEELGGLRYCINSASLKFIPKEELKEKGYEEYLELFK
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: RL21_TETTS
Sequence: MTHSYGYRRQTRKKFAKAYKTKGHVRISRYLTTYKVGEYVDIMVDGSQHKGMPYKLYHGRTGKVFNVNPRSIGVIVHRIVNGRYIEKRLHVKIEHVRPSNVKTALSKRYQANDQAKAEGNKAGKRVSTKRNPGQPLEAVQVQGAVNFQHPKVFREIF
What are the official names of this protein?
60S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
Protein: EFTS_STAAR
Sequence: MATISAKLVKELREKTGAGMMDCKKALTETDGDIDKAIDYLREKGIAKAAKKADRIAAEGLVHVETKGNDAVIVEINSETDFVARNEGFQELVKEIANQVLDTKAETVEALMETTLPNGKSVDERIKEAISTIGEKLSVRRFAIRTKTDNDAFGAYLHMGGRIGVLTVVEGSTDEEAARDVAMHIAAINPKYVSSEQVSEEEINHEREVLKQQALNEGKPENIVEKMVEGRLRKYLQEICAVDQDFVKNPDVTVEAFLKTKGGKLVDFVRYEVGEGMEKREENFADEVKGQMK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KEL10_CAEEL
Sequence: MDISDISASQLATSPPPITTIDFNSSIEESPAKRVKFAPELTKSFEETLSPTVTLVLRNNEETFDRCLLSFYSNYFRVLFSSKFRDSKSTTHRIRLISAPDLHLLLTIPKAFEQGIKPNISLQKAVELLEPSAFLQMSIPLDYITDVICANLTHENIIKIFRLALLYHTTLAVRVWRAMVRKFQTLFATNVYLTLKENELIGLLTDKHLNLKSADEKTVVVNWIKHNSPLQSDRMAQFAQRNFSRQPQPDATKYEVIRTRQPMDAIVCFGGWASRGVAQNIEVFNTRSDRWQTCNFNYDIPNIRRAYHGIEVVEDKLIVYGGFNGTQQFQTTVLFDLSTKEWRSGANMNDKRCYVTSARINDSHGRPLIFACGGMNGVSRLKTAEMYDYRADQWSEVANMAQMRSDGAVVTIDNKIVVIGGFDGRNIHQGGEVYDPVLDLWHPLSSNMRTRRTGCTAVSIMNQVCMIIGGFNGNRRLDSAEIYDMREGLWHPVPSLHTARSNFSACQMDTCSIYVAGGFDGQATTKESERLDLRSKMWQALPDMSEAKSALRMVTLSDHPFLDELFDIPDDTGIITTW
What are the official names of this protein?
Kelch repeat-containing protein kel-10.
Protein: Y2659_CERS1
Sequence: MDLSGSLLIAMPSMADPRFERSLVLICAHSPDGAMGLVINKPVEDLSFAGMLEQLNIPRAPNGRDIRVHLGGPMERGRGFVLHSPDYMSVGATMLVSGKFGMTATVDILEALARGQGPSSALMALGYSGWGPGQLEAEVQRNDWLTAEAPSELVFSDDDPGKWTGMLRHMGIDPLTLSSTAGHA
What are the official names of this protein?
UPF0301 protein Rsph17029_2659.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: RL20_LEPBJ
Sequence: MPRAVNGTIHKNRRRRVLKDAKGFRGARSKLYRTAKSAVMKAGQWAYRDRRAKKRDFRKLWIIRINAAARENGLSYSVFMNSLKKLGINMDRKSLAELAFNDREVFNALVEKIKVAG
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: BGAL2_ORYSJ
Sequence: MAASAVAVAFVVAVAAVLAAAASAAVTYDRKAVVVNGQRRILISGSIHYPRSTPEMWPDLIEKAKDGGLDVVQTYVFWNGHEPSPGQYYFEGRYDLVHFIKLVKQAGLYVNLRIGPYVCAEWNFGGFPVWLKYVPGISFRTDNEPFKAEMQKFTTKIVEMMKSEGLFEWQGGPIILSQIENEFGPLEWDQGEPAKAYASWAANMAVALNTSVPWIMCKEDDAPDPIINTCNGFYCDWFSPNKPHKPTMWTEAWTAWYTGFGIPVPHRPVEDLAYGVAKFIQKGGSFVNYYMYHGGTNFGRTAGGPFIATSYDYDAPIDEYGLLREPKWGHLKQLHKAIKLCEPALVAGDPIVTSLGNAQKSSVFRSSTGACAAFLENKDKVSYARVAFNGMHYDLPPWSISILPDCKTTVFNTARVGSQISQMKMEWAGGFAWQSYNEEINSFGEDPLTTVGLLEQINVTRDNTDYLWYTTYVDVAQDEQFLSNGENLKLTVMSAGHALHIFINGQLKGTVYGSVDDPKLTYTGNVKLWAGSNTISCLSIAVGLPNVGEHFETWNAGILGPVTLDGLNEGRRDLTWQKWTYQVGLKGESMSLHSLSGSSTVEWGEPVQKQPLTWYKAFFNAPDGDEPLALDMSSMGKGQIWINGQGIGRYWPGYKASGNCGTCDYRGEYDETKCQTNCGDSSQRWYHVPRSWLSPTGNLLVIFEEWGGDPTGISMVKRSIGSVCADVSEWQPSMKNWHTKDYEKAKVHLQCDNGQKITEIKFASFGTPQGSCGSYTEGGCHAHKSYDIFWKNCVGQERCGVSVVPEIFGGDPCPGTMKRAVVEAICG
What are the official names of this protein?
Beta-galactosidase 2, Lactase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 35 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: CXXC1_DROME
Sequence: MTDKRKYKKTVSFTRCTAIIFLTTKEVSKQKEEIRREIAREFDLPERKSKIATILKQEDQAYCICRSSDCSRFMIGCDGCEEWYHGDCIGITEKEAKHIKQYYCRRCKKENPELQTIFRLVATERAAASNAASTSLNAPGVGPSGAAPAAAPVASATTSQQAPPPTTAAAKRKNSSAREPKMGKRCGTCEGCRRPNCNQCDACRVRVGHKPRCIFRTCVVQAATVLKESQATQAGPSRKREKAAPKSRNVQVGPRAASPEIFLNPELQGIRQCYGPNCCSHARPQSKYCSDKCGFNLATKRIFQVLPQRLQEWNLTPSRAAEETRKHLDNIRHKQSLVRFALAELEKRSEELNMVVERAKRSSIDTLGSQDTADMEDEQSMYCITCGHEIHSRTAIKHMEKCFNKYESQASFGSIFKTRMEGNNMFCDFYNPASKTYCKRLRVLCPEHSKDPKVNDTDVCGSPLVNNVFNPTGEFCRAPKKNCFKHYAWEKIRRAEIDLERVRQWLKMDDLMEQERVMRQQLTSRANLLGLMLHSTYNHEVMDELVRKQQEHLVEFEKQRRRLAHQQQIQTQQKQYQEKQKLMLQQQQQQQQQQQQQQQQQQQQQLQQPQQQQQQQQQQQQEQQQLQLKPHHLQQLQLQLLQQQQKKAQIPQKTQIIYLQKKT
What is the function of this protein?
Component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3.  Essential for Set1 association with chromatin and trimethylation of histone H3 at 'Lys-4' at transcription puffs.  Additionally, is critical for general chromosomal association of Set1.
What are the official names of this protein?
CXXC-type zinc finger protein 1, PHD finger and CXXC domain-containing protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: AMPA_DESVH
Sequence: MDIRFQAGGHAAWRAGAVMVFVFKDEPLAEVDSQLVEAAPWLTIAPAGNDFRAAKDEVAVLHGPPAFDIPRVVAVGLGKREDCTLERIRLAAAAGIRRCRDLRVENVGVVAAQLGRMAPTEHDALRVAEEVVCGALLGLYRYDRFRTVKDDERAEDPRWLALLCEGKNVPDDLHGAARKGEAVALGMGVARDLVNGPANIVTPAFLASEAEALGRKHGFRVEVLGRDELSSMGMGAFASVFRGAEEEARLIVIEHAPAGTEEQQPLVFVGKGVTFDTGGISLKPAAKMHEMKGDMAGAAAILGLFAALGERDLPRRVVGVLPCTENMPDGRATRPGDVVTTLSGKTVEILNTDAEGRLLLCDALTYAQRRWQPEALVDLATLTGACVVALGTEVAGLFCDDAALADAIASRGETVGDLFWPLPLWKSYAENLKSDVADLANVGPREGGAVNAALFLRQFIDDGVRWAHLDIAGPAFTAKKSALCPGGGTGFAVRTLFELVSEGIPAA
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PQQB_XANC5
Sequence: MRIIVLGSAAGGGHPQWNCHTLASLRAWQQTDGAQRRTQASIAVSADGERWVLINASPDFRQQILATPALWPQHGLRHSPIEAVLLTSGEIDHIAGLLSMRESQRFSLHASSRVLGLLAQNPIFDAVNPQYVSRQPFALDTPLVLCGLQLTPFSVPGKVPLFMESRSGGDLAGSDEETLGLTIDDGRRRMHYIPGCAAMTDALRARLQSAELVFFDGTLWRDDEMVQLGVSQKTGQRMGHMSIDGPDGTIAAFAPLNVARKIFIHLNTTNPVLDTLSPEFASARASGWEVAHDGLEIAL
What is the function of this protein?
May be involved in the transport of PQQ or its precursor to the periplasm.
What are the official names of this protein?
Coenzyme PQQ synthesis protein B, Pyrroloquinoline quinone biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the PqqB family.
Protein: SYE_SALNS
Sequence: MKIKTRFAPSPTGYLHVGGARTALYSWLFARHHGGEFVLRIEDTDLERSTPEAIEAIMDGMNWLNLEWDEGPYFQTKRFDRYNAVIDEMLEAGTAYKCYCSKERLEQLREDQMAKGEKPRYDGRCRHSHEHHADDEPCVVRFANPQDGSVIFDDQIRGPIEFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALNAPVPMYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSSGDQEIFTREEMIKLFSLGAVSKSASAFNTDKLLWLNHHYINTLAPEYVATHLQWHIEQENIDTRNGPQLAELVKLLGERCKTLKEMAQSCRYFYEDFSEFDADAAKKHLRPVARQPLEVVRDKLSAITDWSAENVHHAIQATADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGKTRSIERINKALGFIAERESQQ
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_STRPF
Sequence: MERNQRKTLYGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKKYKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEKAVII
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: NEC1_EBVB9
Sequence: MAPVTPDAVNARQQRPADPALRRLMHPHHRNYTASKASAHSVKSVSRCGKSRSELGRMERVGSVARSICSRHTRHGVDRSHFSLRDFFRGISANFELGKDFLREMNTPIHVSEAVFLPLSLCTLSPGRCLRLSPFGHSLTLGSHCEICINRSQVHVPQEFSSTQLSFFNNVHKIIPNKTFYVSLLSSSPSAVKAGLSQPSLLYAYLVTGHFCGTICPIFSTNGKGRLIMHLLLQGTSLHIPETCLKLLCENIGPTYELAVDLVGDAFCIKVSPRDTVYEKAVNVDEDAIYEAIKDLECGDELRLQIINYTQLILENKQ
What is the function of this protein?
Plays an essential role in virion nuclear egress, the first step of virion release from infected cell.  Within the host nucleus, NEC1 interacts with the newly formed capsid through the vertexes and directs it to the inner nuclear membrane by associating with NEC2.  Induces the budding of the capsid at the inner nuclear membrane as well as its envelopment into the perinuclear space.  There, the NEC1/NEC2 complex promotes the fusion of the enveloped capsid with the outer nuclear membrane and the subsequent release of the viral capsid into the cytoplasm where it will reach the secondary budding sites in the host Golgi or trans-Golgi network.
What are the official names of this protein?
Nuclear egress protein 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae NEC1 protein family.
What are the subcellular locations of this protein?
Host nucleus inner membrane. Note=Remains attached to the nucleus inner membrane through interaction with NEC2.
Protein: PPNP_ECOK1
Sequence: MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEEMTVISGALNVLLPDATDWQVYEAGSVFNVPGHSEFHLQVAEPTSYLCRYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: ARGA_ALIFM
Sequence: MKFRSTALVKGFRQSAPYVNAHRDKTVVIMLGGEAIADPNFANIVNDIALLNSLGLRIVIVYGTRPQMRSLLKQTEHHAPFHKGIRITDEQTLELVKQIAGQLQLDITARLSMSLNNTPMAGAQINVISGNFVIAQPLGVDDGIDYCHSGRVRRIDTQGINRMLDQQSIVLLGPVASSVTGECFNLLSEDVATQLAIRLNADKLIGFCSEQGVLNEKGQILAELFPSEAEEILQRLEKELTPENGKLTGTMRFLKGAISACKAGVPRSHLISYKEDGALIQELFSFDGIGTQVVMASSEQVRDAEIDDIGGILDLIRPLEEEGILVRRSREQLEQEIAQFTIIEKDGLVIACAALYPFPEEGMAEMGCVAVHPDYRDGDRGVILLNRLRAKAKQYKLSQLFVLTTRSLHWFREQGFIEVDVSHLPMKKQKLYNFQRKSKILVLKGL
What are the official names of this protein?
Amino-acid acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ArgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_HAEIN
Sequence: MPAKIRQNDEVIVLTGKDKGKRGKVTKVLPNGKVFVEGINIITKHEKPVPALGKAGGLVKKEAAIDASNVAIFNPKTNKADRVGFRFEDGKKVRFFKSNNEII
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: PAU4_YEAST
Sequence: MVKLTSIAAGVAAIAATASATTTIAQSDERVNLVELGVYVSDIRAHLAQYYMFQAAHPTETYPVEVAEAVFNYGDFTTMLTGIAPDQVTRMITGVPWYSSRLKPAISKALSKDGIYTIAN
What are the official names of this protein?
Seripauperin-4.
What is the protein family that this protein belongs to?
Belongs to the SRP1/TIP1 family. Seripauperin subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: H2B1N_BOVIN
Sequence: MPEPSKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGNMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B type 1-N.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ISPT1_NOSS1
Sequence: MTIQQTELQELPLDLKRELLPKHVAVIMDGNGRWAKRQGLPRIMGHKRGVDALKDLLRCCRDWGIQALTAYAFSTENWKRPQEEVEFLMTLFQRVLRQELREMVEENVQIQFVGNLTALPRSLQAEISRSMEETKNNRGIRFSVATNYGGRQEILQACRAIAQKVQQGLLQPDEINEEVFERHLYTAGISDPDLLIRTSGEMRLSNFLLWQMAYGEIYITDTLWPDFDRTEFHRALCAYQQRERRFGKV
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase 1.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: PSD_SALTI
Sequence: MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKYYKVDMTEAQKPDTASYRTFNDFFVRPLRDDVRPLNTDPNILVMPADGVISQLGRIEEDKILQAKGHNYSLEALLAGNYLMADKFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYVPGDLFSVNYLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTITPPREGIIKRWTWPEGEHEGSVALLKGQEMGRFKLGSTVINLFAPGKVNLIASLASLSVTKIGQPLATSTETFVAPEVEPAPLPAEEIKAEHDASPLVDNKKDDT
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YR557_MIMIV
Sequence: MSQVTGFDQSNVAQYSSFDPLGSLEHAGSNLGNFIQRNNPFPSLSQSASHTFDDVRSDSGKIFDELKSEADKFYDDAKHGLSDIDYRDFYASDPGNTVLRASMQSPYLNSYMDINNAPNVIPLQAPPIVTNRNSKDYNILFVVVILLLLFVAWRCYVNKR
What are the official names of this protein?
Uncharacterized protein R557.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein. Virion.
Protein: RS5_RHOPS
Sequence: MAAERERGGRERSRDREERDSEFVDKLVHINRVAKVVKGGKRFGFAALVVIGDQKGRVGFGHGKAREVPEAIRKATEAAKRNLTRVALREGRTLHHDIAGRHGAGRVYLRAAPAGTGIIAGGPMRAVFETLGIQDVVAKSIGSSNPYNMVRATFDALKHLDSPRAVAARRNIKVSTLQSRRVGGDAEVVAE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: CAPTB_DICDI
Sequence: MSKYFKYISEKGITNLANYHYSGVDNSFCGNKFLKHWWNYCVNFTPLWLAPNIITLVGLLCNIGMYLIMYVHCPTLTEEAPRWCYFAVAFLIFAYQTLDNVDGKQARKTKSSSPLGELFDHVCDALSVAMFAIVMSATLRIGPYWTFFSFIVGMWPFYLAHWEEYHAGILVMGEFNGPTEAQVLFMIIEIITGIFGSDIWTYGTSTTVGKIATVFVSIGAVVTCLQNFTNTYKLENRMTFGKCLLQLTPICLFTALIVIWASVSNLITEQPHLFIMTLGILFGYIQSRYITQRVCHDDCSLFYPIFVPIIIVVLNSILASSDVHLVSETVALWILFSIACAQFLLFSYFTTQQLCDHLKIKVFTIPYPSNSGIGPSQEYENSLLSQMEEGSSSIGNSTDDINPSEIEEI
What are the official names of this protein?
Uncharacterized CDP-alcohol phosphatidyltransferase class-I family protein 2.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.