PharMolix/UniProtQA huggingface dataset:
Protein: NUOH_HELAH
Sequence: MSAYIIETLIKILILVAVFSALGGFATYIERKVLAYFQRRLGPSYVGPFGLLQVAADGIKLFTKEDIIPQGANKLIFTLAPIIAMVSAFVSMAPIPFFPNFTLFGYEIKPIISDINIGFLFFLAVGAAGIYAPILAGLASNNKYSLIGSARATIQLLSFEVVSTLTILAPLMVVGSLSLVEINNYQSGGFLDWLVFKQPLAFILFLIASYAELNRTPFDLLEHEAEIVAGYCTEYSGLKWGMFFLAEYAHLFAFSFVISIVFFGGFNAWGFIPGGIAILIKVSFFVFLSMWVRATYPHVRPDQLMNMCWKIMLPLALLNIVLTGVIILI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CTTB2_CALJA
Sequence: MATDGASCEPDLSRAPEDAAGAAAEAAKKEFDVDTLSKSELRMLLSVMEGELEARDLVIEALRARRKEVFIQERYGRFNLNDPFLALQRDYEAGAGDKEKPVCTNPLSILEAVMAHCRKMQERMSAQLAAAESRQKKLEMEKLQLQALEQEHKKLAARLEEERGKNKQVVLMLVKECKQLSGRVIEEAQKLEDIMAKLEEEKKKTNELEEELSAEKRRSSEMEAQMEKQLSEFDTEREQLRAKLNREEAHTTDLKEEIDKMKKMIEQLKRGSDSKPSLSLPRKTKDRRLVSISVGTEGTVMRSVACQTDLVTESADHVKKLPLTMPVKPSTGSPLASANAKGSVCSSAAMARPGIDRQASHGDLIGVSVPAFPPSSANRIEENGPSTGSTPDPTSSIPPLPSNAAPSTAQTPGITPQNSQAPPMHSLHSPCANASLHPGLNPRIQAARFRFQGNANDPDQNGNTTQSPPSRDVSPTSRDNLVAKQLARNTVTQALSRFTGPQAGAPPRPGAPPTGDVSTHPSVGRTSVKTHGIARVDRGNPPPIPPKKPGLSQTPSPPHPQLKVIIDSSRASNTGAKGDNKTVASPPSSLPQGNRVINEENLPKSSSPQLPPKPSIDLTVAPAGCAVSALATSQVGAWPAATPGLNQPACSDSSLIIPTTIAFCSSINPVSASSCRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLIAYDANINHAADGGQTPLYLACKNGNKECIRLLLEAGTDRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRVPAHGNSFSEEESESGVFDLDEGEESPEGKSKPVVTADFINHANREGWTAAHIAASKGFKNCLEILCRHGGLETERRDKCNRTVHDVATDDCKHLLENLNALKIPLRISVGEIEPSNYGSDDFECENTICALNIRKQTSWDDFSKAVSQALTNHFQAISSDGWWSLEDMTCNNTTDSNIGLSARSIRSITLGNVPWSVGQSFVQSPWDFMIKNKAEHITVLLSGPQEGCLSSVTYASMIPLKMMQNYLRLVEQYHNVIFHGPEGSLQDYIVHQLALCLKHRQMAAGFSCEIVKAEVDAGFSKKQLLDLFISSACLIPVKQSPVKKKIIIILENLEKSSLFELLRDFLAPLENRSTESPCTFHKGNGMSECYYFHENCFLMGTIAKACLQGSDLLVQQHFRWVQLRWDGEPMQGLLQRFLRRKVVNKFRGQVPPPCDPVCKIVDWALSVWRQLNSCLSRLGTPEALLGPKYFLSCPVVPGHAQVTVKWMSKLWNGVITPRVQEAILSRASVKRQAGFRQTIAKRHPSQGQQAVVKAALSILLNKAVLHGCPLPRAELEQHRADFKGGSFPLSIVSSYNSCSKKKGESGAWRKVNTSPRRKSGRFSLPTWNKPDLSTEGIKNKTLSQLNCNRNASLSKQMSLENDVSLTLNLDQRLSLGSDDEADLVKELQSMCSSKSESDISKIADSRDDLRMFDSSGNNPVFSATINNLRMPVSQKEVCPLSSHHTTECSNSKSKTELGVSRVKSFLPVPRSKVTQCSQNTKRSSSSSNTRQIEINNNSKEENWNLHKNEHLEKPNK
What is the function of this protein?
Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, thus controls dendritic spinogenesis and dendritic spine maintenance.
What are the official names of this protein?
Cortactin-binding protein 2, CortBP2.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Cell projection, dendritic spine. Note=Remains associated with dendritic spines even after glutamate stimulation.
Protein: TERB1_MOUSE
Sequence: MESEKPKKTQEMKTDLKLLLECLKYHMGNPLSQKEVLITIHSVCKQNSDAGIYFREIGGLMFIINLAKSSEQSLVKEAALYTLGSIAEENVYCQQSLCTSELFQDLTGLLTNDDSNTNLKRMSVYVLLVLVSNNRNGQTLVREVGCIEVLSQMFRTVLSNYELNLSDNSVFQSYLLWSSVCSTLCVCVNNPQNDENQMLCCSLFPCVNEWLMNCMRPEVIRPICSFIGLTLANNTHAQNCFVSSGGLDVLCQVLVQLESDSHNTLSSAKLAVIVTKTMDACITDNSAAFTVVLSKYHIVSTLLALLLHESLDSREKFSIILAIGHCTEDCEKNQYELLKNNGLPLMIQALTEFKNEDLSKAATYVLHNCKKITGKLSLSLGQNSFGENEIELKDISEKETLREHWKAAKEILCRIKQFEKGGKEEKQQNRSGHYKDNTPSMKVNIQTNLKRLCADSTGGTRAEDKDINQSRELRSYKPSEIMSKACANENQLTTRKKNTNPVHPFCKEKGQSKIVHETTPSCAQNLDKEKTFDQKDSVSQSSDQVLKHLPHTVKNRKQVPETDPFTLCLDIIDREVGIQATDSCSRMLKYTCSGCIVARKLLNSRNFSKFLHSCAYQCVHHKVIMEAEDKYKNELRKTFICAKKILLTPCRRRQLCKESTASEELKIVHQKPDSKKLPGLEAQALNTSIPEAMERRSPVPGQSGLHKKRRIRKDFTKEEVNYLFHGVKTMGNHWNSILWSFPFQKGRRAVDLAHKYHRLIKGPSCAAL
What is the function of this protein?
Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis (PubMed:24885367, PubMed:24413433, PubMed:26548954).  Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes: in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex.  During prophase, the complex matures and promotes release of the shelterin/telosome complex from telomeric DNA (PubMed:26548954).  In the MAJIN-TERB1-TERB2 complex, TERB1 probably mediates association with the shelterin/telosome complex via interaction with TERF1, promoting priming telomeric DNA attachment' (PubMed:26548954).  Promotes telomere association with the nuclear envelope and deposition of the SUN-KASH/LINC complex (PubMed:24885367, PubMed:24413433).  Also recruits cohesin to telomeres to develop structural rigidity (PubMed:24413433).
What are the official names of this protein?
Telomere repeats-binding bouquet formation protein 1, Coiled-coil domain-containing protein 79.
What is the protein family that this protein belongs to?
Belongs to the TERB1 family.
Protein: MEND_STAA2
Sequence: MGNHKAALTKQVFTFASELYAYGVREVVISPGSRSTPLALAFEAHPNIKTWIHPDERSAAFFAVGLIKGSERPVAILCTSGTAAANYTPAIAESQISRIPLIVLTSDRPHELRSVGAPQAINQVNMFNNYVSYEFDMPIADDSKETINAIYYQMQIASQYLYGPHKGPIHFNLPFRDPLTPDLNATELLTSEMKILPHYQKSIDASALRHILNKKKGLIIVGDMQHQEVDQILTYSTIYDLPILADPLSHLRKFDHPNVICTYDLLFRSGLDLNVDFVIRVGKPVISKKLNQWLKKTDAFQILVQNNDKIDVFPIAPDISYEISANDFFRSLMEDTTINRVSWLEKWQCLEKKGRKEIKCYLEQATDESAFVGELIKKTSEKDALFISNSMPIRDVDNLLLNKNIDVYANRGANGIDGIVSTALGMAVHKRITLLIGDLSFYHDMNGLLMSKLNNIQMNIVLLNNDGGGIFSYLPQKESATDYFERLFGTPTGLDFEYTAKLYQFDFKRFNSVSEFKNATLLSETSTIYELITNREDNFKQHQILYQKLSEMIHDTL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: DHYS_THEKO
Sequence: MTEPKDIVLKESEEVEGIPIEGPWLDDVSSLEEVLDYYERIGFQATHLGKAIEIWKKVEKRRAEGKEVRVFLGYTSNIISSGLRELVAWLVKEGKIDVIVTTAGGIEEDFIKALKPFILGDWHVNDALMREKGINRIGNIFVPNDRYIEFEKYMIPFFERVLEIEKERGKPLTASEFIYELGRYMDEKLGKEKERSVIYWAYKRNVPIFCPAITDGSIGDMLYFFKEERGDRELIIDIANDIVKLNNLAVTAKETASIILGGSLPKHAIINANLFRGGTDYAIYITTAVPWDGSLSGAPPSEGVSWGKIRAKADYVEIWADATLVFPLLVWKVMKAP
What is the function of this protein?
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
What are the official names of this protein?
Probable deoxyhypusine synthase, DHS.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: ARRD4_RAT
Sequence: MSSQSSILVDFRPLATSFTGKYGSIQYCVRAVLERPQVPDQSVRRELQVVSHVDVNTPPLLTPMLKTQEKMVGCWLFTSGPVSLSVKIERKGYCNGEAIPIYAEIENCSSRLVVPKAAIFQTQTYLASGKTKTVRHMVANVRGNHIGSGSTDTWNGKMLKIPPVTPSILDCCIIRVYIHIPGAKKLMLELPLVIGTIPYSGFGRRNSSMASQFSMDMCWLALALPEQPEAPPNYADVVSEEEFSRHIPPYPQPSACDGEACYSMFACIQEFRFQPPPLYSESHAQLFCLQPVGPTNRAHF
What is the function of this protein?
Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates.  Plays a role in endocytosis of activated G protein-coupled receptors (GPCRs) Through an ubiquitination-dependent mechanism also plays a role in the incorporation of SLC11A2 into extracellular vesicles.  May play a role in glucose uptake.  Participates in innate immune response by promoting IFIH1/MDA5 activation through interaction with TRIM65.
What are the official names of this protein?
Arrestin domain-containing protein 4, Liver regeneration-related protein LRRG041/LRRGT00117.
What is the protein family that this protein belongs to?
Belongs to the arrestin family.
What are the subcellular locations of this protein?
Early endosome. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle. Note=Also found in extracellular vesicles different from exosomes.
Protein: MDHX1_ARATH
Sequence: MDPNQRIARISAHLNPPNLHNQIADGSGLNRVACRAKGGSPGFKVAILGAAGGIGQPLAMLMKMNPLVSVLHLYDVANAPGVTADISHMDTSAVVRGFLGQPQLEEALTGMDLVIIPAGVPRKPGMTRDDLFNINAGIVRTLSEAIAKCCPKAIVNIISNPVNSTVPIAAEVFKKAGTFDPKKLMGVTMLDVVRANTFVAEVMSLDPREVEVPVVGGHAGVTILPLLSQVKPPCSFTQKEIEYLTDRIQNGGTEVVEAKAGAGSATLSMAYAAVEFADACLRGLRGDANIVECAYVASHVTELPFFASKVRLGRCGIDEVYGLGPLNEYERMGLEKAKKELSVSIHKGVTFAKK
What is the function of this protein?
Catalyzes a reversible NAD-dependent dehydrogenase reaction involved in central metabolism and redox homeostasis between organelle compartments (Probable).  Peroxisomal NAD-dependent malate dehydrogenase involved in fatty acid beta-oxidation.  Reoxidizes NADH from the beta-oxidation and provides NAD for the conversion of fatty acyl-CoA to acetyl-CoA.  Does not participate directly in the glyoxylate cycle (PubMed:17376163, PubMed:19812894).  Required for maintenance of photosynthetic rates under photorespiratory conditions, and carbon flow during photorespiration.  Supplies NADH reductant to the peroxisomal hydroxypyruvate reductase (HPR), which reduces hydroxypyruvate into glycerate in the photorespiratory cycle (PubMed:18685043).
What are the official names of this protein?
Malate dehydrogenase 1, peroxisomal, Peroxisomal NAD-dependent malate dehydrogenase 1, pxNAD-MDH1, Peroxisomal malate dehydrogenase 1, Peroxisomal MDH1.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: NU3C_CUCSA
Sequence: MFLLYEYDIFWVFLIISSVIPILAFLISGVLAPLSKEPEKLSSYESGIEPMGDAWVQFRIRYYMFALVFVVFDVETVFLYPWAMSFDVLGVSVFIEALIFVLILIVGLVYAWRKGALEWS
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: DED1_PICST
Sequence: MTDITQKMNELSVQDGGSGAGNSPGAGNGPSGGNGSRRSQYVPPHLRNRNTSSGSGFGGNGGGRGRGSFGGSNYNNAGNRDNTIFGGSGRSRDRGFGGRGGFRSNQSRPGVGRWVDGKHEPSARNERIELELFGTAEDTSFQSSGINFDNYDDIPVEASGDGVPDPITSFTAPPLDELLVENITMSRFTKPTPVQKYSVPIVAGGRDLMACAQTGSGKTGGFLFPVLSESYINGPAPIAESTGAFSSHKVHPTILVMAPTRELVSQIYDEAKKFAYRSWVKPAVVYGGADIGQQIRNLDKGCDLLVATPGRLKDLLERGRVSLANIKYLVLDEADRMLDMGFEPQIRHIVQECDMPDVQDRQTLMFSATFPTDIQMLARDFLKDYIFLSVGRVGSTSENITQKILYVEDEEKKSVLLDLLSAGDAGLTIIFTETKRMADNLADFLYDQGFPATAIHGDRSQYEREKALAAFKSGAAPILVATAVAARGLDIPNVAHVINYDLPSDIDDYVHRIGRTGRAGNVGIATAFFNRNNKNVVKGLIDLLSEANQEVPDFLAKIGRESAFGGKTGGMRGGRGGSRGPVRDFRRGASGGSSGGWGNSSGSAGGWGAAPSGGNSYNSGYSSRSNSYNSSYGSSGYGNPTSTNSWW
What is the function of this protein?
ATP-binding RNA helicase involved in translation initiation.  Remodels RNA in response to ADP and ATP concentrations by facilitating disruption, but also formation of RNA duplexes (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DED1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_CHLAA
Sequence: MSKKKDVIEMEGTITEPLPNAMFRVQLDNGHEVLAHISGKMRMNYIRILKGDRVLVELSPYDLTRGRITYRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_BRUA1
Sequence: MPSLKDLRNRIASVKATQKITKAMQMVAAAKLRRAQEAAEAARPYSQRMGAVLANIAQNVSGEDAPALMVGTGKDDVHLLVVCTAKRGLCGGFNSQIARLARDHARKLLAEGKTVKIITVGKKGADILRREFSALLHDHVDLREVKQLAFVHADQIGHKIIKLFEEGAFDVCTLFYSEFKSVISQVSTAQQLIPASADNEAEMETAGDAIYEYEPDPAAILSTLIPRNISVQIFRALLENVAGEMGAKMSAMDNATRNAGDMINKLSITYNRQRQAQITKELIEIISGAEAL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RIR2_HHV2H
Sequence: MDPAVSPASTDPLDTHASGAGAAPIPVCPTPERYFYTSQCPDINHLRSLSILNRWLETELVFVGDEEDVSKLSEGELGFYRFLFAFLSAADDLVTENLGGLSGLFEQKDILHYYVEQECIEVVHSRVYNIIQLVLFHNNDQARRAYVARTINHPAIRVKVDWLEARVRECDSIPEKFILMILIEGVFFAASFAAIAYLRTNNLLRVTCQSNDLISRDEAVHTTASCYIYNNYLGGHAKPEAARVYRLFREAVDIEIGFIRSQAPTDSSILSPGALAAIENYVRFSADRLLGLIHMQPLYSAPAPDASFPLSLMSTDKHTNFFECRSTSYAGAVVNDL
What is the function of this protein?
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis.  Allows virus growth in non-dividing cells, as well as reactivation from latency in infected hosts.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase small subunit, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: MUTS_BORAP
Sequence: MEKNVTPMMRQYLDIKKKYKDAIIFFRVGNFYEMFFDDAIEASKLLNLTLTKRENVPMCGVPYHTSKEYIRKLILFDKKVAICEQAANSTSVGPLEREVVEVITPGVIVDEDFLNDDVNNYLVAISDYKNYYSFSYIDLSTSSLGIMFYENSFFEKLKRDLEKYSPKEIIVSENFYYEYSEKLNLNRFLINRVPAWHLDKDVAIKTIKEHFNILGLSSLGFDEEKPYYISIFLIINHIKNNLKNLLSNIDKIDINNDSLYMFLDDVTQVNLELVKNNNDFSSQYSLYSVLNDCKTAMGKRLLREFILNPILNIPEINTRLDHVEFFCKNISLTMTLREAFVNIWDVERIISRIQMKRYIKKDFLFIEKSLSVFFLVKKLFDKHNFDYWNFDKFEEDSISKVYFLINSAISSSSDELIKRGYDLKLDSLKDLKINANKYIDEYLESERLLSKINNLKIRKTNNRGLFFEVTKSNYAQVPPHFMESQTLNSSKRYKTEKLISLEANINNAEDSVVAFEQEIFDEIASNVVKHNKVLKKVAEFFAYIDLVVNFGYLAKKNEYKRPILTCSKEIFLEKSRHPVVEHYVKNTEIFTENFVKINKEKYFCLITGPNMAGKSTYLRQVALITLMAHIGSFVPASRAVIGITDKIFCRIGASDNLAKGESTFLVEMNETANILRNATEKSLIIMDEVGRGTSTNDGLAIAYSIIEYILEYIKARSLFATHFHELSAINHKAFINLSMKIEKQGNELVFLREVEEKPSLNSYGIYVARIAGLPLRVVDRANVILKSLGSRKDSSCLEFLPCISSDTCDREVLKNDTDVHVKLNEYLELKKFISNIDINNITPFQSIELLNQLVLKVISQSS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RL29_SYNY3
Sequence: MALPNIADARKLGDEELATEILATKQRLFQLRFQQATRRPENPHEFKHARHRLAQLLTVERERQLENSPSEEA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: Y598_TREPA
Sequence: MGCCTLGLFADSVEKRAAKDVFTEPARFYPSQKSTLESARSDTSESENASSSVPSHSQQELAPDSAAPARNSVLSPAPPERREKQGTAVHGAEVTRAGAVSPRFVGGLTKILAASDHTFFAAGNDGFLTQYTYPDYKPDTWQITPVSIKHCAVHPDRARIAVYETDGRNYHRVSVWNWRTKEILFAKRFTASVVSLSWIVQGSFLSVGTASREGVTVLDGSGNTVSLFSEEPGVVLLTASGPRLVLSYAESGRLTYVDYSKKTTVKRLLTEKNLLSPMLIHNGAHLVGYRDQRVYVIQSSSGAVLTEYPARSACFAHTFSDSLPVWIEPAELKYHWRIRKAAQRSADFMLPDNARITSACSVRTRVIVGTDRGILYELQQGDDRRVTIRALNGERQIYASDVHGADEGAYFLADGSLYHSMASGGPYRVLVRGVKGTRFLPYRDGFIVWSAGKETEFLHCAQKTSQHRMIYRARSTVSGVSVYGRMLVITEPFSGVSVVDIERGIRVFFHKAIGMQDSLLITDDVIVATQSGLQPLVLLHMRTGETYTQRWEAICLGVRAHDTQHVYFFSLDTNAGTTDLIHFVCNCSNPQKVLCDASSLIRMRI
What are the official names of this protein?
Uncharacterized protein TP_0598.
Protein: TBB1_ELEIN
Sequence: MREILHIQGGQCGNQIGAKFWEVICDEHGIDHTGKYAGDSDLQLERINVYYNEASGGRFVPRAVLMDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVLDVVRKEAENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLATPTFGDLNHLISATMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQQYRALTVPELTQQMWDSKNMMCAADPRHGRYLTASAMFRGKMSTKEVDEQMLNVQNKNSSYFVEWIPNNVKSSVCDIPPNGLKMASTFIGNSTSIQEMFRRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVAEYQQYQDATAEDEEEYEDEEEEMAA
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-1 chain, Beta-1-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ATGT_SULTO
Sequence: MVGEFEIKDEDLAGRIGIIETKSGKLETPVFFPVINPFKSEISIKDIENLGFKNLITNAYLIKKITNTKIQDIHSFLQFNGVIMTDSGAYQILQYGNIEVTNREIVEYERDINTDIAVYLDLPTGDTNSRDEAINSVKITLERAKEIEDIVKNDSERIWVHPIQGGRFLDLVEYSAIEADKNEAFKMLALGSPTVVMEKYDYSLLIDMVFIAKSNVSRGKPFHLFGGGLPHIMPLVIALGVDSFDSASYILYARDNRYITRSRVYRLEELEYFPCSCPICLKYTPKELLELPKEERTKLLALHNLYVIKEELNAIKQAIREGRLFEYIQEKAYSHPAVYSAFKKILKYKDYLEKYDPRVKGNIRGIFLFDLKSLNRPEIVRHYNFLDRINKNNDKAIIICEKRENILKKVKNNENVDIYLFNPFYGLIPINLIEVYPYFQTEYPEEIDEDVLRYIESKIVEFVRSKGYTKIDFIGCEKYLSHINSIGAFFS
What is the function of this protein?
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
What are the official names of this protein?
tRNA-guanine(15) transglycosylase, 7-cyano-7-deazaguanine tRNA-ribosyltransferase, Archaeal tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the archaeosine tRNA-ribosyltransferase family.
Protein: MNMG_TREPS
Sequence: MGFRFSDYDVIVVGGGHAGAEAALAAARMGEHTLLITQTIDSIGRLSCNPSIGGISKGNIVREIDALGGEMGKFADACMIQYRLLNKSRGPAVQAPRIQADKFLYAQKVKYTLECTQHLHLYQDTVVDVVCSNTTDAGYVAYGAAHAVVTARGRRISARAVVLTTGTFMEGRVYIGEYEAPEGRLGEHAAEGLGAALRKKGFQMGRLKTGTPARVLRKSVDLSVMEKQEADAIMRPFSFAHVEINRPHADCYINYTNERTHQLIRENFHRSPFFSGRIKAVGTRYCPSIEDKVRKFPDRIRHQLYIEPEGLDTEELYINGLSSCLPEDIQDEMIRTIPGMERAVITRPAYAVDYAVLFPVQLGIDLQTKRVSGLFSAGQINGTSGYEEAGGQGIIAGINAALYARSTKTKEEYHPFVLKRDEAYIGVMIDDLVTQGIDEPYRMFTARAEYRLKLRHDTADERLTEKAYAIGLQKKSAVETLQKKMRTKHEILHLLQTNKVSLTHANAYVQLKPHIGKSFAATLRDPVIPLGLIASLNEQIAQFPLEVFQSVGVEIRYEHYIAAQDQRIAQVEKMEGIKIPAHFDYARISGLSVESRTRLEHVRPDTIGQVGRMRGIRPSDVMLLLAHLKR
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DOXA_STRC0
Sequence: MSGEAPRVAVDPFACPMMTMQRKPEVHDAFREAGPVVEVNAPAGGPAWFITDDALSRYVLADPRLVKDPDLAPAAWRGVVDGLDIPVPELRPFTLIAVDGEAHRRLHRIHAPAFNPRRLAERTDRIAAIAGRLLTELADASGRSGEPAELIGGFAYHFPLLVICELLGVPVTVPMAREAVSVLKALASAAQSGGGDGTDPAGGVPDTSALESLLLEAVHSARRNDTPTMTRVLYEHTQAEFGSVSDNQLVYMITGIIFAGHERTGSFLGFLLAEVLAGRLAADADEDAVSRFVEEAVRYHPPVPYTLWRFAATEVTIGGVRLPPGAPVLVDIEGTNTDGRHHDAPHAFHPDRPSWRRLTFGDGPHYCIGEQLAQLESRTMIGVLRSRFPEARLAVPYDELRWCRNGAQTARLTELPVWLR
What is the function of this protein?
Involved in the biosynthesis of the anthracyclines carminomycin, daunorubicin (daunomycin) and doxorubicin (adriamycin) which are aromatic polyketide antibiotics that exhibit high cytotoxicity and are widely applied in the chemotherapy of a variety of cancers.  In vivo, DoxA catalyzes the C-13 hydroxylation of 13-deoxycarminomycin and 13-deoxydaunorubicin to yield 13-dihydrocarminomycin and 13-dihydrodaunorubicin, respectively, as well as the oxidation of these 13-dihydro-anthracyclines to their respective 13-keto forms, carminomycin and daunorubicin.  In vivo, it also catalyzes the C-14 hydroxylation of daunorubicin to form doxorubicin.  It can only use NADP.  DoxA acts jointly with DnrV.
What are the official names of this protein?
Cytochrome P-450 monooxygenase DoxA, 13-deoxycarminomycin C-13 hydroxylase, 13-deoxydaunorubicin C-13 hydroxylase, 13-dihydrocarminomycin C-13 hydroxylase, 13-dihydrodaunorubicin C-13 hydroxylase, Daunorubicin C-14 hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF3_STRZJ
Sequence: MFFSNKTKEVKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADNANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGDFDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKMDGRQMFMQLAPATDKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MG101_DICDI
Sequence: MKRFISTTSLRVLSNLNKNNNNNNKFNKSIVGVFNREFSSSNEGLNKVNFGENNNSSTTEPTKVLFNDSQFYQEDKYQGISKEPFSKEIVDTLLADLNPDDIEIKPDGLIYLPEIKYRRILNQAFGPGGWALKPFGPPVVEGKTLIRPYALYCLGRYVAESIGEQQYVPNSFISFATATESAKSNALVRCCKDLGIGSSLWDPIFIRQWKSEYATERWCENSKTKERRLFWFLSNRSENQLPYPWKESDFNQVPSNSSYSSSSSSINNNSNSSNNNNNNSDSSSSINQPQQETISYHQDDSSSPSSKITEQQDDSEDIDIDDVVPPQLKKYAGKTWRQLVADPKGLSYLQWASSSFDNAPKIKSQATAILEFINKSQ
What is the function of this protein?
Performs an essential function in the repair of oxidatively damaged mtDNA that is required for the maintenance of the mitochondrial genome.  Binds to DNA (By similarity).
What are the official names of this protein?
Mitochondrial genome maintenance protein mgm101 homolog.
What is the protein family that this protein belongs to?
Belongs to the MGM101 family.
What are the subcellular locations of this protein?
Mitochondrion matrix, mitochondrion nucleoid.