PharMolix/UniProtQA huggingface dataset:
Protein: ARAA_BACTN
Sequence: MNNVFDQYEVWFVTGAQLLYGGDAVIAVDAHSNEMVNGLNESGKLPVKVVYKGTANSSKEVEAVFKAANNDDKCVGVITWMHTFSPAKMWIHGLQQLKKPLLHLHTQFNKEIPWDTMDMDFMNLNQSAHGDREFGHICTRMRIRRKVVVGYWKEEETLHKIAVWMRVCAGWADSQDMLIIRFGDQMNNVAVTDGDKVEAEQRMGYHVDYCPASELMEYHKDIKNADVDALVATYFNDYDHDASLEDKSTEAYQKVWNAAKAELALRAILKAKGAKGFTTNFDDLGQTDGSYFDQIPGLASQRLMAEGYGFGAEGDWKSAALYRTVWVMNQGLPKGCSFLEDYTLNFDGANSSILQSHMLEICPLIAANKPRLEVHFLGIGIRKSQTARLVFTSKTGTGCTATVVDMGNRFRLIVNDVECIEPKPLPKLPVASALWIPMPNLEVGAGAWILAGGTHHSCFSYDLTAEYWEDYAEIAGIEMVHINKDTTISCFKKELRMNEVYYMLNKALC
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: NUP61_SCHPO
Sequence: MSKRGADHQLTKDQDDSDDDRHGPVEVPKEASADVMATRKIAKPKSRKRPTSGVSSPGIFANLAAKPVSLPASTTQFTFGKPAVTANNDSDIHLKKRGLNKSFIDAVIKSVDNNPFGNLSPLFDEYRQHFSSIEKKPAEEQPTSNAVVSEVNPQQQKSQDSSSFVTEKPASSEKEDKEKPLVPPGAPRFGFSAPALGSSFQFNSSAFTPKGSFGEKSATEAEAKEKETSSNQTATGTAATTTNQFSFNTAANPFAFAKKENEESKPLTPVFSFSTTMASADASKETKQTHETKDSKSEESKPSNNEKSENAVEPAKGNTMSFSWTPDKPIKFDTPEKKFTFTNPLSSKKLPASSDVKPPSAAAVGFSFGTTTNPFSFAAPKSSFPTSSTPASVGAEKSEETSNGNKSEQEEKENGNDETRSNDSLVSGKGKGEENEDSVFETRAKIYRFDATSKSYSDIGIGPLKINVDRDTGSARILARVEGSGKLLLNVRLCQDFEYSLAGKKDVKVPAASTDGKSIEMYLIRVKEPSTAEKLLAELNEKKVSKSEN
What is the function of this protein?
Functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope.  May play a role in mitotic spindle formation and/or function.
What are the official names of this protein?
Nucleoporin nup61, Nuclear pore protein nup61.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex.
Protein: Y766_MYCPU
Sequence: MKKLGIIIDSFTSITEDEFKKLEDFYFLPLQLILDGTSYEDNPSNDRQKLFDKIIQASDIKTSLPISSTIEKAVNESSQKYNDVLVLPIASFLSGTISVINVYAQKHKNVHIFDNHFVANTIVEIGLQAKKMYEQENKSIKEIITWLEEINTKTITFLSLKTLDYLVKGGRISGVKKFILTKLKLFPIIQSYTNNSIAGLKRTFKSSLEKIYNKLAEFIGGENNFKNYNLKLVHGPSKEMVDGAVEFFKQKGLEFSSIVLASTVIIAHTGPDSISISVVPKY
What is the function of this protein?
May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
What are the official names of this protein?
DegV domain-containing protein MYPU_7660.
Protein: DHYS_HALS3
Sequence: MTGDDADETHENVVPGSDEDLDTPDVRGYDFSGEFDFFELLDSYATTGFQASHLADAVDITREMREDDATIYLTLTSNIVSSGLREVVAHLVRENYVDVIITTSGSLTEDIIKTAKPFKMGEWDVDEAALREEGINRLGNIFVPSDRYVWLEEYLYDFFEEFFADQKVRTPTAFARELGATLDDEDSILKNAADNDIPVFCPALTDAEIGNFLYYYRQGYDSEVGIEILDDYDALIEEGLLADTTGLICVGAGVPKHHAIMTNLFRGGADYAVYISTGMEGDGSLSGAPPEEAVSWGKIKDEDAEPNYALIEAEATLVFPLLVAGAFENP
What is the function of this protein?
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
What are the official names of this protein?
Probable deoxyhypusine synthase, DHS.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: RF1_STAEQ
Sequence: MFDQLDIVEERYEQLNELLSDPDVVNDADKLRKYSKEQADLQKTVDVYRSYKTKKEELQDIEDMLNETSDKEEVEMLKEESSALKTELPDMEEELKILLIPKDPNDDKDVIVEIRAAAGGDEAAIFAGDLMRMYSKYAEANGFKTEIVEASESDHGGYKEVSFSVSGTGAYSKLKFENGAHRVQRVPETESGGRIHTSTATVAVLPEAEDVEIEIRNEDLKIDTYRSSGAGGQHVNTTDSAVRITHLPTGVIATSSEKSQIQNREKAMKVLKARLYDMKLQEEQQKYASQRKSAVGTGDRSERIRTYNYPQSRVTDHRIGLTLQKLNQIMEGNLDEIVEALTLSEQTEKLKELNNGEL
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM2_AQUAE
Sequence: MIVGRFPSSRPRRLRRNENIRRLVRETHLTLDDLIYPIFVRWGENVVEEVPSMPGVYRYSVDKVVDAVKEVRDLGIPAIILFGIPEHKDEVGSDTWSEEGIIQRALRKIKKEVPDIYVITDVCFCEYTTHGHCGVLHDHDVENDLTLENLKKQVVSHAENGADMVAPSGMMDGMVKVIREALDEAGFKHIPIMAYSAKFASAYYGPFREAAESAPAFGDRRTYQMDPANSREALKEVLMDVEEGADVVMVKPALAYLDIIAKVKENVLVPVCAYNVSGEYSLIKAAGKLGWIDEKKVMWETLLSIKRAGADMIITYFAKDAARMIIEGEV
What is the function of this protein?
Catalyzes an early step in the biosynthesis of tetrapyrroles.  Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).
What are the official names of this protein?
Delta-aminolevulinic acid dehydratase, ALAD, ALADH, Porphobilinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the ALAD family.
Protein: GIGA6_CRAGI
Sequence: MSSRNLLYSSVVLFLVLFYCHGGPLEDRVRSTIQEVYKNCRKDKNPGVIVSVVKDGQNVLTEALGVKDKISGEAITTDTLFGLGGISALFANILIAKKNAEYAEMDEDTTLRNLFGNNKLFEKSKLRSRYATSLDVMAHRLGFKNTPHLFLDDTVTRGDPVIQRISSMKPRGRFRDSFYYNELTYSILTTIGERLGRDSWENLVKNEIYTPLGMAKSKFFTTLDPSTVDIARAYKEDDGSLFPVPFEFLKKWSSLCSTTCVLSSANDMSKFMNYLLGQRKPSWTKPCVTGPRKFTLILFDAI
What are the official names of this protein?
Gigasin-6.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RLMG_SHEDO
Sequence: MTSQFSTAGLTLELLRYPSQQVSNLQAWDAADEHIIKVLAEKVLEENAVPPQPCAIINDSFGALSCALTRMDSSWPLTVISDAKTSQLGALENLTRNQLDAEGIKWLTSRAPLPQDLSLVLMKLPKNLAYFAQQLRGLSQVLPQGTQVLIGAKAKSINSALITLLAEHLGPASASLAWKNTRVITCVSDGRARSLPKAITWSVPEYQLEISNLSNVFAANKLDIGARIMLENMPNGEFNTVVDLGCGNGILGLRAAGLYPKAKIHFIDDSEMAVASSQANWALNTLAPERAEFHWDDCMSHLDETVQPDLVLCNPPFHQGEAITDHIAWQMFNDAKHRLRSGGILHIVGNRHLNYHVKLKRLFGNCTTVASNGKFVILQSVKG
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK1_BACC1
Sequence: MKFTIMSKGDQSSDALASTMKEYLLDFGFIMDEQEPDIVISVGGDGTLLYAFHRYYNRLDETAFVGVHTGHLGFYADWLPTEVEKLVIAIAKTPFQVVEYPLLEVIIRYVNGSKESQYLAMNEATVKSAEGTLVTEVEIRGEYFETFRGDGLCISTPSGSTAYNKALGGAIIHPSIEAIQIAEMASINNRVFRTVGSPLVLPKHHTCVLKPTAGMNLQITVDHLTMVHQDVKSIQYRVANEKVRFVRFRPFPFWKRVRDSFVADK
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase 1, ATP-dependent NAD kinase 1.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15E_AERPE
Sequence: MALSMYHYIAREWKKPYEGLHGELMKARLLEWRRQPSILRVEKPTRLDRARALGYKAKQGVIVARVRVRKGGRRKPRPNKGRRPKRMGVYGFAPAKSLRLIAEERAQRKYPNLVVLNSYYVGEDGRYKWYEVILVDPNHPAIKNDPELNWVTTGKHKGRPFRGLTSAGKKMRGLRKSRGLKGTHKYKWKKKAKERILRKRHEASRGARLIEPDEIREKFHKGDLT
What are the official names of this protein?
50S ribosomal protein L15e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
Protein: SDC_CUTMO
Sequence: MRGKVSLEEAFELPKFAAQTKEKAELYIAPNNRDRYFEEILNPCGNRLELSNKHGIGYTIYSIYSPGPQGWTERAECEEYARECNDYISGEIANHKDRMGAFAALSMHDPKQASEELTRCVKELGFLGALVNDVQHAGPEGETHIFYDQPEWDIFWQTCVDLDVPFYLHPEPPFGSYLRNQYEGRKYLIGPPVSFANGVSLHVLGMIVNGVFDRFPKLKVILGHLGEHIPGDFWRIEHWFEHCSRPLAKSRGDVFAEKPLLHYFRNNIWLTTSGNFSTETLKFCVEHVGAERILFSVDSPYEHIDVGCGWYDDNAKAIMEAVGGEKAYKDIGRDNAKKLFKLGKFYDSEA
What is the function of this protein?
Reversibly catalyzes the regioselective carboxylation of phenol to form salicylic acid.  Involved in a pathway for the degradation of salicylate via phenol.  Also catalyzes the decarboxylation of beta-resorcylic acid (2,4-dihydroxybenzoic acid) into resorcinol (1,3-dihydroxybenzene), gamma-resorcylic acid (2,6-dihydroxybenzoic acid) into resorcinol, 2,3-dihydroxybenzoic acid into catechol (1,2-dihydroxybenzene), and 4-aminosalicylic acid into 3-aminophenol.
What are the official names of this protein?
Salicylate decarboxylase, Salicylic acid decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily.
Protein: EX7L_ENTFA
Sequence: MTQQYLTVTALTKYLKRKFDADPYLGRVYLTGEISNFRFRANAHQYFSLKDDHAKISAIMFKSAFQKLKFQPKEGMKVMVVGRISLYENSGSYQIYIEHMEPDGVGALYQALAELREKLGKEGLFEGPKQQLPRYPKRIAVVTSPSGAVIRDIITTVKRRYPIAQLVLFPTLVQGEQAADDIVRNIQRADAQSDFDTMIIGRGGGSIEDLWPFNEEKVARAIHAATTPIISSVGHETDVTIADMVADVRAATPTAAAELAVPVLNEELLRISERRSRLEQSFLYLLQQRTERFQRLQNSYVFKQPERLYEGQTIKLDRMTQRLFQAMTTIHHQKQRQAQGIIAQLQQQTPKGQLRESQQQLAFLQRNLQTQMTQLFLNKQKQFTSAVQQLDLLSPLKIMGRGYSYTTKEDRVVKTVTELQPADQLTIHYADGTVQANVETITAKKEEF
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_DROSI
Sequence: MAGPLPPLNQEPAFQKLQEYYDSKAKDLNIKDLFVKDSKRFSKYSLRLHTQNDGEILLDYSKNRINDEVWDLLLALAKVRRVNAARDAMFSGQHINITENRAVLHTALRNRGTDPVLVDDKDVMPDVRAELAHMKEFTNMVISGVWRGCTGKQITDVVNIGIGGSDLGPLMVTEALKPYGKGLHSHFVSNIDGTHLAEVLKKVNYETTLFIVASKTFTTQETITNATSAKTWLLEHSKEPESVAKHFVALSTNKEKVTEFGIDSTNMFGFWDWVGGRYSLWSAIGLSICLSIGFENFEQLLDGAHFMDNHFKTTPFEKNAPVILALLGVWYSNFFKAETHALLPYDQYLHRFAAYFQQGDMESNGKFVSKSGKPVKYSTGPIVWGEPGTNGQHAFYQLIHQGTRLIPCDFIAPAQTHNPIAGGKHHKILLSNFLAQTEALMAGKTVDEARTELSKAGLCGNELDNLLPHKVFVGNRPTNSIVVKKVSPFTLGALIALYEHKIFVQGIIWDINSFDQWGVELGKQLAKAIEPELDHCNEVSTHDSSTNGLINFIKANWK
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_BACFN
Sequence: MRSIEVKGTARTIAERSSEQARALKEIRNNGGVPCVLYGGEEVVHFTVTNEGLRNLVYTPHIYVVDLVIDGKKVNAILKDIQFHPVKDTILHVDFYQIDEAKPIVMEVPVQLEGLAEGVKAGGKLALQMRKLKVKALYNIIPEKLTINVSHLGLGKTVKVGELSYEGLELLNAKEAVVCAVKLTRAARGAAAAAGK
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: NUOA_SALG2
Sequence: MSMSTSTEVIAHHWAFAIFLIVAIGLCCLMLVGGWFLGGRARARHKNVPFESGIDSVGTARLRLSAKFYLVAMFFVIFDVEALYLFAWSTSIRESGWVGFVEAAIFIFVLLAGLVYLARIGALDWTPARSRRERMNPETNSIANRQR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DPEH1_SCHPO
Sequence: MVSDSKLELPLPVNQQKPRRRRILKVHLLIAALILSAVGYLGKGKWIWTPERKAHFVLTHFPLIDGHNDLPIYLRENYDNRLLNISLEHLPGQTDIFRLRQGHVGGQFWSVFVECPSLDSNSSLSWNRTGEYEAVTQTLQQIDVVKRMALYYPKTFSLTDHSGKVKFDFLRNHISSMMGIEGLHQIAGSPSILRQFYDLGVRYATLAHNCDNVFADAAVDGKRTNKGLSPAGRDIVREMNRLGMIVDLSHTTPETMHQALDVSVAPAFFSHSSAKGVYDHPRNVPDDVLIRVKETDGVVMVNFYPAFISPHPENATIDTVVEHIMHIANVTGSYRHIGLGGDFDGIDMVPKGLEDVSKYPDLFVKLAERGLSITELADIAGRNVLRVWKTTEDLGHSIHEPPLEWEDDF
What are the official names of this protein?
Uncharacterized dipeptidase C3A11.10c.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
Protein: DDI1_KLULA
Sequence: MNITVTYEHSDDVLGPFELSEDMSLIDLFALIDFKEESQIIFHNMKQLDTKNTNITLKEAGLQNHDMLLIKPKNPASSQAAFGQPQEIDLTDEQYIEQFRTFLLENPSMAQEMGLPNLEHMINNKTQFHQLLGPVLLSRRGERSNNPFGIPNSEYSRLMSNPDDPVNQARISELTNQHEIDEQLRYAMEYTPESFTQVSMLYIKLEINGHPVKAFVDSGAQQTIMSTKLAERTGLTSLIDKRFSGIAQGVGTGKILGRIHTTQIKIHDVFLPCSFTVLDTPMEMLLGLDMLRRHQASIDLKNNVLRISDVETPFLPESEIPKDSLHALTTPAADEVRKAALKRDSSSGKNAMTGDANKVKQPKIPSSTTNQTVPSFAESDIKKLVDLGFSRKEAINALNKTGGNVDYAASLLFQ
What is the function of this protein?
Probable aspartic protease.  May be involved in the regulation of exocytosis.  Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquitin for their subsequent degradation.  Required for S-phase checkpoint control.
What are the official names of this protein?
DNA damage-inducible protein 1.
What is the protein family that this protein belongs to?
Belongs to the DDI1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_MYCLB
Sequence: MSDIPSDLHYTAEHEWIRRSREDTVRVGLTDFAQSTLGDVVFVQLPEVGAELAAGKSFGEVESTKSVSDLYAPVSGTVSAVNTDLEGSPQLVNSDPYGAGWLLDVHVSDVGALESAIATLLDAETYRGTLTK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: RF1_VIBC3
Sequence: MKASILSKLESLVERYEEVQHLLGDPTVIGDQNKFRALSKEYSQLEEITQCFQAYQQAKEDLVAAEEMAQEDDAEMREMAQDEIKAAKAAIERLTDELQILLLPKDPNDDRNCFLEIRAGAGGDEAGIFAGDLFRMYSRFAEKKGWRIEVMSSSEAEHGGYKEMIAKVNGDGAYGTLKFESGGHRVQRVPATEAQGRIHTSACTVAVMPEIPEAEIPEIKASDLKIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKAMSVLAARIAQAEESKRAAEISDTRRNLLGSGDRSDRIRTYNYPQGRVSDHRINLTVYRLTEVMEGDMQSLIDPVIHEHQADQLAALADQN
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIW_BORRA
Sequence: MKNKFSIKVKFPEGILGFEDIKEFIIKDSAHKPFSIMQSINGEINFLVTSPFNFLEKYLPNIENKDWLDIQAENENEKVILCIINMHVKNYKEITANLKAPIILNKKKLIGKQAISTNEEHYLRYRVFKE
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNN_ECO55
Sequence: MKIGIIGAMEEEVTLLRDKIENRQTISLGGCEIYTGQLNGTEVALLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGLAPTLKVGDIVVSDEARYHDADVTAFGYEYGQLPGCPAGFKADDKLIAAAEACIAELNLNAVRGLIVSGDAFINGSVGLAKIRHNFPQAIAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQSSLMVESLVQKLAHG
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.  Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: NRDR_ACTP7
Sequence: MRCPFCAAEETKVVDSRLAADGYQIRRRRECTSCKERFTTFESAELVVPYVIKNNGNRVPFDANKLRVSLSRALEKRPVSADDLEKAISKIIIQLQSTGEREVPSKLVGSLAMDALKQLDKVAYIRFASVYLSFDDIEEFTKEIEKLRE
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: Y984_RICBR
Sequence: MFAFFRSSSNEPDGTLYNKLIEAIKSRNSLEVLALIPKMKNEELAKPNIYGNTPLSLALNKKLEAVCEVLVSRMSDKDISIIETYVEHRETYFTLAAIKGFKGVCENLAPRMSNEAINVINARKHTALTLAADKNLPQVCIKLIPIMFDEVINVTENRHKDSALRKAIWNDLDVVCQMLIPVTSKENINYIDVSDRTLLILAAQKGMKVVCKMLISRMIEDNSLDIINHVISKGELKGESALSLAEKQKGFEDICELLQKSHEEYKEQKQKENEKKCEESQPKKIISEDINKLLNELKDGAYNNKNIIEFSISAKIEKLEKNANDLSEIYTNIQDIINHNKNTKAKLLALEKHLNQIIDAQTINTEQQISLEALGDVSVEFSNSRGV
What are the official names of this protein?
Putative ankyrin repeat protein RBE_0984.
Protein: COAX_SYNJA
Sequence: MSSEAERWLAAVVGNTHVRWGWFAGESLVKVEQFPAHQPLSWPEETELWLAAVGSAPLPPRSPWVHCLELSQVPLRDPYPSLGLDRALALWAAGIRYGWPCLVIDAGTALTLTGADAEGSLVGGAILPGLGLQAQALADHTARLPKVEWDPGAPIPPRWARNTGAAIRSGILHTLLAGLRDFLADWRRRFPQGPLLVTGGDGELLYPHLRPLDAELRWDPHLVLRGIAGCRQLHRVVRKPSGAE
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_ROSS1
Sequence: MAKYIFVTGGVASSVGKGITVASIGRLLKARGVRVSVQKLDPYINVDPGTMSPYQHGEVFVTEDGAETDLDLGHYERFIDVNLTRLSNVTTGQIYSAVIQKERRGDYLGGTIQVIPHITNEIKSRIAAVARQTGADVVIVEIGGTVGDIEGLPFLEAIRQMRKDVGRDNVLYIHVTLLPHIGATGEVKTKPTQHSVMELRRVGITADVIVCRSDYPITDEIRDKIALFADVDVEAVVPLHTVDSIYEVPLVLEEAGLGAYLTQRLGLSASRPDLDDWRDLVARIKAPKRKLAIALVGKYVELHDAYISVVEALRHAGLHQGVDVDIRWISSEQIEEEGCEPLLHDVYGIVVPGGFGDRGIEGKIAAAEYARVNNVPYLGLCLGMQVATISFARHIMGPESRANSTEFDLHTPHPVIDFMPDQLDITDKGGTMRLGGYPCKLTPGTRAYAAYGVDVVVERHRHRFEFNNKYRRLFESAGMIVSGQSPDGRLVEIIELRNHPWYVGTQFHPEFQSRPDRPHPLFRDFVAAAAKTFREGDQRPLPLEQNGAVTEHEPHSR
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: PAP1_CNPV
Sequence: MDRRNQITSVIREYLGRNPVPKEYEVLKKQTLKLSKIINFNKDTFFFLIKKNKYTFFKDLNVSDEEIQERIDEYFTKQRRARRLGNLLAIVELQKLLVSSFTKTLGVLTTKALEYYPSNIRLDYSFMEKIADNILDSYNVVKPSEEVKGRHKVSDLVLHVNKIMEEYLRRHSNSCICYGSYSLHLLNKKIEYGDIDILQTNARIFLINIAFLIRFITGRCVVLLKVPFLKNYVVIHDENLNHVMDSFNIKQSTMDKIPKIMIDNMYIVDPCIQLLNTIKMFSQIDRLEDIHTKFDKLSIRLGTLLEYTRYRYSILLDSESILDVKYKIDIQNRKIILDFKKYNLNYIKCYFFLDEDELKKLIRKTPKTDDYIDLEAVTNSEYMILNKTMYTYFSNTTLLRSKDELHPITINALTSHALLYHVITKKFYDDLLGDLIRSLMIVEKVPVYEIIPRDKKRGKHTIIDIEKDVVFH
What is the function of this protein?
Polymerase that creates the 3'-poly(A) tail of mRNA's.
What are the official names of this protein?
Poly(A) polymerase catalytic subunit, Poly(A) polymerase large subunit, PAP-L.
What is the protein family that this protein belongs to?
Belongs to the poxviridae poly(A) polymerase catalytic subunit family.
Protein: IF1_HELPH
Sequence: MARDDVIEVDGKVIEALPNATFKVELDNKHVVLCRISGKMRMHYIRIALGDRVKLELTPYSLDKGRITFRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_STAA2
Sequence: MAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_RHIE6
Sequence: MERAEKREFVTELNEVFKASGSVVVAHYAGSTVAQMNDFRSKMRAAGGTVKVAKNRLAKIALQGTEAEGMSNLFKGQTLIAYSNDPITAPKVVMDFAKTNDKIVVLGGAMGTTTLNAEAVKSLATLPSLDELRAKLLGMIQTPATRIVGVVAAPASQLARVFAAYAKKDEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: CCA_XANOM
Sequence: MKIYLVGGAVRDALLGQPAGDRDWVVVGADQARMEAQGFKPVGKDFPVFLHPRSGEEYALARTERKSGRGYRGFVVDADPLVTLEEDLLRRDFTINAIARDEDTGEFFDPYNGARDLQARVLRHVGPAFVEDPVRVLRAARFMARLAPLGFTIAPETAALMREMAASGELDSLVPERVWQELRRALTCAQPSAFLRTLHDTDGLRAILPEIDALYGVPQRAQFHPEVDTGIHQEMVSDMAARIAPGDALVGFAALTHDLGKALTPPEQWPRHIMHEQRGVAPLQALCERLKVPQDYRQLAVIACREHLNVHRLPELRDRTVHELLVRCDAFRRPERIAQLALVCEADKRGRLGSEEAAYPQGAELKRLHAAASAINARDLAADGLQGPQIGEALTKARIAAITAARKTSA
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.