PharMolix/UniProtQA huggingface dataset:
Protein: CLPX_SHEPA
Sequence: MGEDKGNGDGGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKQDQDKLPTPHELRAHLDDYVIGQDKAKKVLAVAVYNHYKRLRNASPKDGVELGKSNILLIGPTGSGKTLLAETLARVLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVDTSKILFVCGGAFAGLEKVIEQRAHVGTGIGFGAQVKGEADKKTISDTLLEVEPEDLVKFGLIPEFIGRLPVLATLSELDDEALIQILSEPKNAITKQFAALFEMENVELEFRDDALKAIALKAQTRKTGARGLRSIVEGILLDIMYDLPSTDDVAKVVIDESVVKGESSPILIYANNEAQTATAE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: ANMK_SALTY
Sequence: MKSGRFIGVMSGTSLDGVDVVLAAIDETMVAQQASLTWPIPVHLKKGILDICQGQPLTLSQLGQLDTQLGRLFAQAVNALLAQQRLQPRDIVAIGCHGQTVWHEPTGEAPHTLQIGDNNHIVAHTGITVVGDFRRRDIALGGQGAPLVPAFHHALLGHPTEKRMVLNIGGIANLSLLFPGQAVRGYDTGPGNMLMDAWIWRQCAQPYDKDAAWAKEGQVILPLLQKMLRDPYFAASAPKSTGREYFNYGWLERHLAAFPGADARDVQATLAELTAVSIAQQVLLNGGCERLMVCGGGGRNPLVMARLAALLPGIEVSTTDKAGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGATEASVLGAIYPANPITQS
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: RS19_BACC4
Sequence: MARSLKKGPFVDDHLMSKMEKLVASEQKQVVKTWSRRSTIFPQFIGHTIAVYDGRKHVPVYITEDMVGHKLGEFAPTRTYKGHLADDKKTRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: BNP1_BOTJA
Sequence: MVLSRLAASGLLLLALLALSVDGKPVQQWAQSWPGPNIPPLKVQQWAQGGWPRPGPEIPPLTVQQWAQNWPHPQIPPLTVQQWAQGRAPGPPIPPLTVQQWAQGRAPHPPIPPAPLQKWAPLQKWAPLLQPHESPASGTTALREELSLGPEAASGVPSAGAEVGRSGSKAPAAPHRLSKSKGAAATRPMRDLRPDGKQARQNWGRMAHHDHHAAAGGGGGGGGGARRLKGLAKKGAAKGCFGLKLDRIGTMSGLGC
What is the function of this protein?
Snake venom natriuretic peptide that exhibits hypotensive and vasodepressor activity.  Acts by activating natriuretic receptors (NPR1 and/or NPR2 and/or NPR3) (By similarity).
What are the official names of this protein?
Bradykinin-potentiating and C-type natriuretic peptides, BPP-CNP.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm, cytosol. Note=BPP-10c is internalized in the cytosol of prey cells.
Protein: DCTA_RHIE6
Sequence: MIAAPLDAVADSKGRKPFYSHLYVQVLAAIAAGILLGHFYPELGTQLKPLGDAFIKLVKMVIAPVIFLTVATGIAGMSDLKKVGRVAGKAMLYFLTFSTLALVIGMIVANVVQPGAGMNIDPASLDPKAVATFADKAHEQSIVGFLTNIIPTTIVGAFADGDILQVLFFSVLFGIALAMVGEKGEQVVNFLNALTAPVFKLVAILMKAAPIGAFGAMAFTIGKYGVGSIANLAMLIGTFYITSLLFVFIVLGAVARYNGFSIVALLRYIKEELLLVLGTSSSEAALPGLMNKMEKAGCKRSVVGLVIPTGYSFNLDGTNIYMTLAALFIAQATGINLSWGDQILLLLVAMLSSKGAAGITGAGFITLAATLSVVPSVPVAGMALILGIDRFMSECRALTNLVGNAVATIVVARWENELDTAQLARALGGQTEEGAPAGGLQPAE
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: XDJ1_YEAST
Sequence: MSGSDRGDRLYDVLGVTRDATVQEIKTAYRKLALKHHPDKYVDQDSKEVNEIKFKEITAAYEILSDPEKKSHYDLYGDDNGAASSGGANGFGDEDFMNFFNNFFNNGSHDGNNFPGEYDAYEEGNSTSSKDIDIDISLTLKDLYMGKKLKFDLKRQVICIKCHGSGWKPKRKIHVTHDVECESCAGKGSKERLKRFGPGLVASQWVVCEKCNGKGKYTKRPKNPKNFCPDCAGLGLLSKKEIITVNVAPGHHFNDVITVKGMADEEIDKTTCGDLKFHLTEKQENLEQKQIFLKNFDDGAGEDLYTSITISLSEALTGFEKFLTKTFDDRLLTLSVKPGRVVRPGDTIKIANEGWPILDNPHGRCGDLYVFVHIEFPPDNWFNEKSELLAIKTNLPSSSSCASHATVNTEDDSNLTNNETISNFRIIHTDDLPEGIRPFKPEAQDSAHQKARSSYCCIQ
What are the official names of this protein?
DnaJ protein homolog XDJ1.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: CYAH_RHOSO
Sequence: MTSPEDTAGVEAALAAEGFSPTDVRAVMCMTESDGFGRGYASLAFAHAFAPALGCPPEDVAQQIPMIMIGGCSGLVTPYAAVFVDDPASSWVTDGSGGGLSIGVTTTATLNPLDVGTPAMVDAVADAVRSAMAAAGIDKVADVHNVQIKTPWPSSAALLDGPLSGLDAGSVGAMARAAGALGVAVALGEVSRADITADVFLRDPNLRSDVASVSAGTERVDAAVLVMGNSPTSASPYRIGHGVLRDGIDPHGVLDALRAVGIDSGWPFTADTTPVEHVFLKSAVDGTDECRGRRHVLRTDYLGPYSWLLGKAVVHATVASIVGDPMMQVSGGGEHQGPPGGGTVAVIAR
What is the function of this protein?
Cyclic amide hydrolase of unknown substrate specificity.  Catalyzes the hydrolytic ring-opening of a cyclic amide.  Does not act on cyanuric acid nor barbituric acid.
What are the official names of this protein?
Cyclic amide hydrolase, CyAH, Ring-opening amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the cyclic amide hydrolase (CyAH) family.
Protein: TRMD_MYCGE
Sequence: MKITVLTLFENTIWPYLNSSIMLQAQKANLVQFEVVNWRNFCNDKHKTVDDMAYGGGSGMVLKAEPIINCLNFYKAPNSHVVLLSPEGEQFSQNCAKKLTKYEHLILLSGHYEGFDQRIYKYIDQIVSLGDFVLSGGELVALSVIDATVRLIKGVINDQSLICESFNDNLLDFPVYTRPYDLKGDKVPEVLLSGDHQKIESFRKEQQILKTAKYRPDLYKKYLENKNEKNK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSS_MYCLE
Sequence: MTSRPRSRRAVNLQILPSSMTVLSICAGLTSIRFALEHQPKAAIALIAAAAILDGLDGRVARILGAESRMGEEIDSLADAVNFGVAPAVVLYATMLSTTPVGWVAVLLYPVCVVLRLARFNALLDDGTQPAYTREFFVGMPAPAGAVSVIGLLALKLQFGAGWWTSTWFLCIWVTGTSMLLISRIPMKKMHTVSVPPHYAAVFVAMLAIFAAAVVLAPYLLIWVIILTYLCHIPFAIHNQRWLAAHPEAWDDKFKQQHDARRAARRACPNRHAVPRLGLLKPGSRSMVRSGLRKPGRRFI
What are the official names of this protein?
CDP-diacylglycerol--serine O-phosphatidyltransferase, Phosphatidylserine synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FADR_SHEB2
Sequence: MIINAKGPASFAEKYIVRSIWDNKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLKIQHGKPTRVNNFWETSGLNILETIADLNPEGFPVLVDQLLSARTNVSAIYFRGALRYNPDTAVDVLAKIHQLEDTAESYAEFDYLLHHTLAFSSGNPLYVLILNGFKGLYSRVGRYYFTSSDARLLALNFYKELELLAQVKNYLDVPALMRTYGMNSGKMWLQLRDDMPASIAQDN
What is the function of this protein?
Multifunctional regulator of fatty acid metabolism.
What are the official names of this protein?
Fatty acid metabolism regulator protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_AQUAE
Sequence: MLMLEREKLARLIKKRSLKVADEPVFKLSSGKLSRYYVDLKQITFDPEGDYLIGKAMYELVKEFNPDACGGLTLGADPIAYAIAFVSLMDSNPIKPFVVRKEPKGHGMKRQIEGLLNPGERVAVLEDVVTTGSSALKAVKACREYGLEVIGVFAVVDREEGGRENIEKEGIPLYSLFKLSELL
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: AQY1_YEAS8
Sequence: MSSNDSNDTDKQHTRLDPTGVDDAYIPPEQPETKHHRFKISKDTLRNHFIAAAGEFCGTFMFLWCAYVICNVANHDVALVAAPDGSHPGQLIMIAIGFGFSVMFSIWCFAGVSGGALNPAVSLSLCLARAVSPTRCVVMWVSQIVAGMAAGGAASAMTPGEVLFANSLGLGCSRTRGLFLEMFGTAILCLTVLMTAVEKRETNFMAALPIGISLFIAHVALTAYTGTGVNPARSLGAAVAARYFPHYHWIYWIGPLLGSILAWSVWQLLQILDYTTYVTAEKAASTKEKAQKKVKPAVPLLWLKSNFSLLFFISRSLALNVIIFGKN
What is the function of this protein?
Water channel required to facilitate the transport of water across membranes.  Involved in sporulation, freeze tolerance and osmotolerance.  Is non-functional in most laboratory strains.
What are the official names of this protein?
Aquaporin-1.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: Y1633_STRA3
Sequence: MNKQERLGMSVYLYYNRDARKLYKYGDVHYHSRRLRYLVIYVNKEDIVSVSKEIKHLKFVKDVRLSAIDDIDQDFVGNLYR
What are the official names of this protein?
UPF0298 protein gbs1633.
What is the protein family that this protein belongs to?
Belongs to the UPF0298 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_GEOTN
Sequence: MSKMRVYEYAKKHNVPSKDVIHKLKEMNIEVNNHMTMLEADVVEKLDHQYRVNSEKKAEKKTEKPKRPTPAKAADFADEEMFEDKKETAKAKPAKKKGAVKGKETKKTEAQQQEKKLFQAAKKKGKGPMKGKKQAAPASKQAQQPAKKEKELPKKITFEGSLTVAELAKKLGREPSEIIKKLFMLGVMATINQDLDKDAIELICSDYGVEVEEKVTIDETNFETIEIVDAPEDLVERPPVVTIMGHVDHGKTTLLDAIRHSKVTEQEAGGITQHIGAYQVTVNGKKITFLDTPGHEAFTTMRARGAQVTDIVILVVAADDGVMPQTVEAINHAKAANVPIIVAINKMDKPEANPDRVMQELMEYNLVPEEWGGDTIFCKLSAKTQDGIDHLLEMILLVSEMEELKANPNRRALGTVIEAKLDKGRGPVATLLVQAGTLKVGDPIVVGTTYGRVRAMVNDSGRRVKEAGPSMPVEITGLHDVPQAGDRFMVFEDEKKARQIGEARAQRQLQEQRSVKTRVSLDDLFEQIKQGEMKELNLIVKADVQGSVEALVAALQKIDIEGVRVKIIHAAVGAITESDILLATTSNAIVIGFNVRPDTNAKRAAESENVDIRLHRIIYNVIEEIEAAMKGMLDPEYEEKVIGQAEVRQTFKVSKVGTIAGCYVTDGKITRDSKVRLIRQGIVVYEGEIDSLKRYKDDVREVAQGYECGVTIKNFNDIKEGDVIEAYIMQEVARA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_THEP1
Sequence: MSERKIPKEVIEEVERLREEIEYHNYRYYVLNDPVITDEEYDKLMRRLIELERMYPELVTPDSPTQRVGGKVLEGFKTVKHSVPMLSLDNTYNEEEILEFDRRVKKTLQEAEVEYVAELKIDGVSIALRYENGKFVLGATRGDGIEGEDVSENVKTVRSIPLRLRKPVTVEVRGEIYMPVDEFKRLNDEREEEGLPPFANPRNAAAGTLRQLNTALVAARRLDSFIYYVVHPENYGLKTQWEALQFLKELGFKVNPHSKLCKNIQEVIDYWREWEERKKELDYWVDGVVVKVNRFDFQRILGETSKAPRWAIAFKFPAEQARTRVLDVTIQVGRTGVLTPVAELEPVQLAGTIVKRASLHNFEYIREKDIRIGDYVFVEKAGGIIPQIVKSIPELRTGSEKEIKPPDKCPVCGGKVGKLDPEEVALRCLNPHCPAKLKRALRTLVSREALDIEGLGEKLIDRLVDAGLVKDIADIFYLTPFDLAQLGPGIGQRTIAKILQEIEEAKKRPLHKLITGLGIPMVGQKTAKILAEHFKSLEAIADASYETLKDIPGIGPEIAKSIVEYFRNPKTREIIEKLKKAGVKLEERVMKLDILKGLTFAVTGTLKNFTREEIVEFFEKLGAKVVNSVSRNTDYLIVGENPGSKYEKAKMLKVKTMSEEEFLEFVRKRAELKGYNFDEIMRSWKEWS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RS21_PSEPF
Sequence: MPAVKVKENEPFDVALRRFKRSCEKAGVLAEVRSREFYEKPTSERKRKAAAAVKRHAKKVQREQRRAVRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RBFA_SYNJA
Sequence: MATARRVARVAELIKREVSQILLSEIKDDRVGAGMVSIVDVEVSNDLQNARIFVSIYGDEAAQQQTMEGLASATPFVRREIGQRLGLRRVPTVVFLQDRSLERGSRVLALLNQLRQPAEAQQQEGSHPGVEGRMADTPGGEEDELSEQQ
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLPP1_CAVPO
Sequence: MFDKARLPYVALDVLCVVLAGLPFAILTSRHTPFQRGIFCNDESIKYPYKEDTIPYALLGGIMIPFSIVVMIIGETLSVYCNLLHSNSFIRNNYIATIYKSIGTFLFGAAASQSLTDIAKYSIGRLRPHFLSVCDPDWSKVNCSDGYIEYYVCRGNAEKVKEGRLSFYSGHSSFSMYCMVFVALYLQARMKGDWARLLRPTLQFGLVAASIYVGLSRISDYKHHWSDVLTGLIQGAIVAILVAVYVSDFFKARNSPFQERKEEDSHTTLHETPTAGNHYRSNHQP
What is the function of this protein?
Magnesium-independent phospholipid phosphatase of the plasma membrane that catalyzes the dephosphorylation of a variety of glycerolipid and sphingolipid phosphate esters including phosphatidate/PA, lysophosphatidate/LPA, diacylglycerol pyrophosphate/DGPP, sphingosine 1-phosphate/S1P and ceramide 1-phosphate/C1P (PubMed:18215144).  Also acts on N-oleoyl ethanolamine phosphate/N-(9Z-octadecenoyl)-ethanolamine phosphate, a potential physiological compound (By similarity).  Through its extracellular phosphatase activity allows both the hydrolysis and the cellular uptake of these bioactive lipid mediators from the milieu, regulating signal transduction in different cellular processes (By similarity).  It is for instance essential for the extracellular hydrolysis of S1P and subsequent conversion into intracellular S1P (By similarity).  Involved in the regulation of inflammation, platelets activation, cell proliferation and migration among other processes (By similarity).  May also have an intracellular activity to regulate phospholipid-mediated signaling pathways (By similarity).
What are the official names of this protein?
Phospholipid phosphatase 1, Lipid phosphate phosphohydrolase 1, PAP2-alpha, Phosphatidate phosphohydrolase type 2a, Phosphatidic acid phosphatase 2a, PAP-2a, PAP2a.
What is the protein family that this protein belongs to?
Belongs to the PA-phosphatase related phosphoesterase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein. Membrane, caveola; Multi-pass membrane protein.
Protein: Y332_TREPA
Sequence: MRAECSAFRYFLKGDGDLVLSVYIRVLCVFLEPVQRGSCSL
What are the official names of this protein?
Uncharacterized protein TP_0332.
Protein: DHB8_CALJA
Sequence: DWDKVIAVNLKGTFLVTQAAGQALVSSGCSGSIINISSIVGKVGNMGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVMNKITGMIPMGHLGDPEDVADVVAFLASEDSGYITGAS
What is the function of this protein?
NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol.  Has very low activity towards testosterone.  The heterotetramer with CBR4 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis.  Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD.
What are the official names of this protein?
Estradiol 17-beta-dehydrogenase 8, 17-beta-hydroxysteroid dehydrogenase 8, 17-beta-HSD 8, 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit, KAR alpha subunit, 3-oxoacyl-[acyl-carrier-protein] reductase, Testosterone 17-beta-dehydrogenase 8.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CCME_PHOPR
Sequence: MNPRRKKRLTLAVALVFGLGATIGLMLYALSQNMDLFYTPTELVQGKPDGTKPEVGQRLRIGGMVVEGSVKRDPQSLIVTFEVADVGPAVTITYNGILPDLFREGQGIVAQGVLVNSTTIEAHEVLAKHDEEYMPPEIAEAMKKTHEPLQYSDEQKQGRVQ
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: RL4_META3
Sequence: MKVKVYNMDGSEKGETELSAVFETEYRPDLIKRAFLSSFTARLQPKGVDLMAGKRTSAKSIGKGHGRARVQRTGQGAGAFVPQAVGGRRCHPPKVEKILHERVNKKERLKALASAIAASANIEMVKNRGHVVETVPSVPLIVSDDFESLKKTKEVLETFKNLGLDGDVQRAKDGIKIRSGIGKLRGRKYRKPKSVLVVVSGACDAVKASKNLPGVDVISANDLGVMHIAPGADSGRLTLWTESAVEEINKRF
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: TGT_STRPM
Sequence: MTDYPIKYRLIKTEKHTGARLGEIITPHGTFPTPMFMPVGTQATVKTQSPEELKAIGSGIILSNTYHLWLRPGDELIARSGGLHKFMNWDQPILTDSGGFQVYSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYDYVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVAMDFPGYSIGGLAVGESHEEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTRIARNGTCMTSEGRLVIKNAKFAEDFTPLDHDCDCYTCQNYSRAYIRHLLKADETFGIRLTSYHNLYFLVNLMKKVRQAIMDDNLLEFRQDFLERYGYNKSNRNF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: AMPA_PSEPW
Sequence: MELVVKSVAAASVKTATLVVPVGEGRKLGAVAKAVDLATDGAISAVLKRGDLAGKPGQTLLLQNLPGLKAERVLLVGSGKDEALGDRAWRKLVASVAGVLKGLNGSDAVLALDDIAVSNRDAHYGKYRLLAETLLDGEYVFDRFKSQKAEPRALKKITLLADKAGLTEVERAARHATAIATGMAFTRDLGNLPPNLCHPSYLAEQAKELGKAHKGLKVEVFDEKKIKDLGMGAFYAVGQGSEQPPRLIVLQYQGAKKSDKPFVLVGKGITFDTGGISLKPGAGMDEMKYDMCGAASVFGTLRAVLELKLPINLVCILACAENMPSGNATRPGDIVTTMSGQTVEILNTDAEGRLVLCDALTYAERFKPQAVIDIATLTGACIVALGSHTAGLLGNNDELIGQLLDAGKRADDRAWQLPLFDEYQEQLDSPFADIANIGGPKAGTITAACFLSRFAKAYNWAHLDIAGTAWVSGGKDKGATGRPVPLLTQYLLDRASA
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YABA_OCEIH
Sequence: MGNREIFDQVSDMEKQIGELYEQLGDLKVKLSDLLEENHRLAHENHHLRHHLEEYRQDGDTDSKQPLNETKKKHHTLPGEGYDNLARLYEEGFHICNLEFGSPRRNEDCIFCLDFFDKTK
What is the function of this protein?
Involved in initiation control of chromosome replication.
What are the official names of this protein?
Initiation-control protein YabA.
What is the protein family that this protein belongs to?
Belongs to the YabA family.
Protein: PKRI1_CHICK
Sequence: MAAPSAPRPPRPRKEPQPLVIPRNAAEEQRLRLERLMRNPEKTVPIPEKLNEWAPRPPPEFVRDVMGSSAGAGSGEFHVYRHLRRREYQRQDFMDAMAEKQRLDEEFQKKLERNKMIAEEQTAKRRRKRQKLKEKKLQAKKNKLEQKKQEKESDQSQERVSSEDDEEDSKEEEEKEDDAEEPSFVMGRG
What is the function of this protein?
Required for pre-mRNA splicing as component of the spliceosome (By similarity).  Binds double-stranded RNA (By similarity).
What are the official names of this protein?
PRKR-interacting protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the PRKRIP1 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus.
Protein: RL15_DESPS
Sequence: MLTLGNLSPQEGSTKQRKRLGRGPGSGHGKTAGRGHKGFKSRSGSGIKPGFEGGQMPLQRRLPKRGFTNIFKKEFSLVALSQLDKFEAGVVVSPAELVEAGMVKKGTLIKILANGEITKAVTVKVDKISSQAKAQIEAAGGTVVLTEVTAAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: TYSY_RHIL3
Sequence: MKQYLDLLNHVMEKGSDRGDRTGTGTRSVFGYQMRFDLEEGFPVLTTKKLHLRSIIHELLWFLKGETNIRYLKENGVSIWDEWADENGDLGPVYGAQWRSWPAPDGGHIDQIANLVKGIVNNPNSRRHIVSAWNPAEVDEMALPPCHCLFQFYVADGKLSCQLYQRSADIFLGVPFNISSYALLTMMVAQVVGLKPGDFVHTLGDAHLYHNHFDQAKLQLARRPKPLPFMRIKPDVKDIFGFTFDDFELIGYEADASIKAPIAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_SALPA
Sequence: MTATAQQLEFLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALSIELLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPRKLPRETIAETYELEYGTDQLEIHVDAIKPGDNVLVVDDLLATGGTIEATVKLIRRLGGKVTDAAFIINLFDLGGEQRLEKQGITCYSLVPFPGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_STRZT
Sequence: MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQVIDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHGRVKALADAARENGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: MSHD_PROFC
Sequence: MNPVVTGPIIRLSADDRDHIADLVRACTEHDGVSPLNESGWFGLQGLTASHTHWIARDGKQVVGYAQADAREHTVQLMVAPPARRQGIATTLAKAAWQLHPAMWWSFGDCPGARELATQLGLREVRKLLKMSLPMPADQPHDAHLPEGLRLDHFRDDDLDQLVAVNHAAFVHHPEQGAMTAEDARNRMAQDWFDPAGLLVARDEAGTLVGFHWTKVADEDGRPRGEVYVLGVDPDFEGKGVGRALLDAGILHMRELGVEAIDLYVEGANERVVHMYERAGFSVVSTDVGYAPAKPARHQDHGRQSSPQERDA
What is the function of this protein?
Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
What are the official names of this protein?
Mycothiol acetyltransferase, MSH acetyltransferase, Mycothiol synthase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. MshD subfamily.