PharMolix/UniProtQA huggingface dataset:
Protein: PSB_MYCA1
Sequence: MTWQFPDRLSTNSALPGPAFSGQPAVDLSSFADFLRRQAPELLPAALGGAQSGPASSSGGTGQLPHGTTIVALKYPGGVVLAGDRRSTQGNMIAGRDVKKVYITDDYTATGIAGTAAIAVEFARLYAVELEHYEKLEGVPLTFAGKVNRLAIMVRGNLAAAMQGLVALPLLAGYDIDARDPEGAGRIVSFDAAGGWNLEEEGYQSVGSGSIFAKSSMKKLYSQVVDADSAVRVAIEALYDAADDDSATGGPDLVRGIYPTAVTIGAEGALEVPESRIAELAREVIQSRSRADTFGPDAAGGDK
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PrcB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TG209_CAEEL
Sequence: MLKLLAFVALLSVSVSANVDMTGFGLPADNHKVALGGPIQESAGLADEGEQQLQLVDVSPQDEGQQNVAHVREMFSNVFNSIKTQREQAMAANGSQPTD
What are the official names of this protein?
Putative protein tag-209.
Protein: SYFB_ACIAD
Sequence: MKISESWLRTWVNPAIDSTTLADQLTMLGLEVDELAPVAKPFTGVVVGEVLTVEQHPDADRLRVTTVNIGNGEPLQIVCGAPNLRVGMKAPVATIGAVLPGEFKIKKGKLRGIESQGMLCGASEIDLEDKIDGLLELPEDAPVGLNIREYLKLDDNIIDISITPNRGDCFSIRGIARDLAVLNQLEVTPPDIQAVEATLNEQKQVHLETEGAPRYLGRIIKNVNVKATTPEWMAQALAASGIRTHSILVDVTNYVLMELGQPMHAFDLAKLNGAIHVRQASAQEKLTLLNDQNVELNEDIMVIADDAKVLAIAGIMGGLESSVTDDTQDIFLESAFFAPLAIAGRARRFGLHTDSSQRFERGVDFELPLLAMNRASQLIQQFAGGEFGPITVAENTALLPKREAIELNQQQVSQLLGYEVETDFIADALTRLGCQVAVKAQGEWVVVAPSHRFDITIYQDLIEEVARIHGYDNIQIRLPKIDVKLAKYQDHLELGQLRQTIATLGYQEAISFSFADLKLEKQLNPDVNPLALANPISSDLAVMRSTLLSSLIPCVQHNLNRQQNRVRFFELGLRFDYQNAASIHDLQQTPTLALIAVGSSVPEQWHGKTQPMDFFDLKHDIEQILAAGRVKVEYVRSERAWLHPGQSAEILIAGQSIGYLGRLHPSLENDLDLGVTWVAELDQQAILQSYVSNFTELSRFPSVRRDIALLISDKINVSDIQQLIKQTGGDLLDSTWLFDVYTGQGVEEGKRSLAFALLWQHPSRTLEDAEIKSGMDNIIEVLENTYQATLRAS
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_SHEDO
Sequence: MSKAVVVFSGGQDSTTCLIQALTQFDEVHAITFDYGQRHNEEIEVAKALASQLRIASHKVMDVSLLNELAISALTRDDIPVSHELMENGLPNTFVPGRNILFLTLAGIYAYQLGANSVITGVCETDFSGYPDCRDQFVRAMETALCLGMDKQINLLTPLMWLNKAETWALADKYHSLTLVKELTLTCYNGIIGQGCGDCPACHLRQKGLDDYLNHKPSVMASLEQKTHGKSA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: PROA_BURMA
Sequence: MDIDQYMTDVGRRARRASREIARASTAAKNAALEAVARAIGRDADALKAANARDVARAKDKGHDAAFVDRLTLSDKALKTMIEGLRQVATLADPIGEMSNLKYRPSGIQVGQMRVPLGVIGIIYESRPNVTIDAAALCLKSGNATILRGGSEALESNTALAKLIGEGLAAAGLPQDAVQVVGTADRAAVGKLITMTEYVDVIVPRGGKSLIERLINEARVPMIKHLDGICHVYVDDRASVAKALAVCDNAKTHRYGTCNTMETLLVARGIAPAVLTPLGRLYREKGVELRVDADARAVLEAAGVGPLVDATDEDWRTEYLAPVLAIKIVDGIDAAIEHINEYGSHHTDAIVTEDHDRAMRFLREVDSASVMVNASTRFADGFEFGLGAEIGISNDKLHARGPVGLEGLTSLKYVVLGHGEGRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBM24_MOUSE
Sequence: MHTTQKDTTYTKIFVGGLPYHTTDASLRKYFEVFGDIEEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRIMQPGFAFGVQQLHPALIQRPFGIPAHYVYPQAFVQPGVVIPHVQPTAAAASTTPYIDYTGAAYAQYSAAAAAAAAAAAYDQYPYAASPAAAGYVTTGGYSYAVQQPITAAAPGTAAAAAAAAAAAAAFGQYQPQQLQTDRMQ
What is the function of this protein?
Multifunctional RNA-binding protein involved in the regulation of pre-mRNA splicing, mRNA stability and mRNA translation important for cell fate decision and differentiation (PubMed:25313962, PubMed:26844700).  Plays a major role in pre-mRNA alternative splicing regulation (PubMed:25313962, PubMed:26844700).  Mediates preferentially muscle-specific exon inclusion in numerous mRNAs important for striated cardiac and skeletal muscle cell differentiation (PubMed:25313962, PubMed:26844700).  Binds to intronic splicing enhancer (ISE) composed of stretches of GU-rich motifs localized in flanking intron of exon that will be included by alternative splicing (PubMed:25313962).  Involved in embryonic stem cell (ESC) transition to cardiac cell differentiation by promoting pre-mRNA alternative splicing events of several pluripotency and/or differentiation genes.  Plays a role in the regulation of mRNA stability.  Binds to 3'-untranslated region (UTR) AU-rich elements in target transcripts, such as CDKN1A and MYOG, leading to maintain their stabilities.  Involved in myogenic differentiation by regulating MYOG levels.  Binds to multiple regions in the mRNA 3'-UTR of TP63, hence inducing its destabilization.  Promotes also the destabilization of the CHRM2 mRNA via its binding to a region in the coding sequence.  Plays a role in the regulation of mRNA translation.  Mediates repression of p53/TP53 mRNA translation through its binding to U-rich element in the 3'-UTR, hence preventing EIF4E from binding to p53/TP53 mRNA and translation initiation.  Binds to a huge amount of mRNAs (By similarity).  Required for embryonic heart development, sarcomer and M-band formation in striated muscles (PubMed:25313962, PubMed:29358667).  Together with RBM20, promotes the expression of short isoforms of PDLIM5/ENH in cardiomyocytes (By similarity).
What are the official names of this protein?
RNA-binding protein 24, RNA-binding motif protein 24.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: TPIS_HUMAN
Sequence: MAPSRKFFVGGNWKMNGRKQSLGELIGTLNAAKVPADTEVVCAPPTAYIDFARQKLDPKIAVAAQNCYKVTNGAFTGEISPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSDAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ
What is the function of this protein?
It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
What are the official names of this protein?
Triosephosphate isomerase, TIM, Methylglyoxal synthase, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3L22_DENPO
Sequence: RTCNKTPSDQSKICPPGENICYTKTWCDAWCSQRGKIVELGCAATCPKVKAGVEIKCCSTDNCNKFKFGKPR
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
What are the official names of this protein?
Alpha-elapitoxin-Dpp2c, Alpha-EPTX-Dpp2c, Long neurotoxin 2, Neurotoxin delta, Toxin TN2.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RISB_PROMA
Sequence: MVSIEGRFTEASSLKIGIVAARFNDLITSKLLSGCIDCLTRHGIDTSESSSQLDIAWVPGSFELPLVSQTMAKSGRYQVLITLGAVIRGDTPHFEVVINESSKGIASVSRETGVPIIFGVLTTDTMQQALERAGVKNNLGWNYALQAIEMGSLMKALK
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: F16PA_BORBR
Sequence: MKRKTLTQYLVEQQRSAQALGPEVRLLIEVVARACKAISHAVSKGALGGVLGSLESENVQGEVQKKLDVLSNEILLEANEWGGHLAAMASEEMETIHLIPNRYPKGEYLLLFDPLDGSSNIDVNVSIGTIFSVLRAPHRVAGADVCEQDFLQPGSQQVAAGYAVYGPQTMLVLTIGNGVVGFTLDREMGSWVLTHESMRIPEDTKEFAINMSNMRHWAPPVKRYIDECLAGKTGPLGKDYNMRWIASMVADVHRILTRGGIFMYPWDAREPGKAGKLRLMYEANPMGLIVEQAGGAAIDGTGRILDIQPDKLHQRVSVILGSKNEVERVGRYHAEAHAS
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFSA_GEOUR
Sequence: MQLPIPLFPATLIRRYKRFLADFELESGEIVTAHCPNSGSMKGCATPGSPAFLSRSDKPERKLKYTWELVKADGCWIGINTGLPNRLVREAIENGLVAELQGYQTIRPEVRYGENSRIDLLLCNADQLCYVEVKNVTLVEGNAVLFPDAATTRGQKHLRELMGVVRQGHRAVNFFVVQRADGEFVAPADLIDPEYGRLLRQAAANGVEILAYRAHVAPEGINITGKLSVRM
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: PIMT1_GEOUR
Sequence: MKLHFVKNLADRREIMMNYHLLARGIRDPAVLKAMLEVPREAFVAEGMEELAYDDYALPIDEGQTISQPYIVAYMAESLELSAADRVLEIGTGSGYAAAVLSRIVSTVYTVERLAGLARSAHQRLEMLSYGNIHVLEGDGTLGWPEYAPYDAIVVTAGAPDLPKPLLSQLSVGGRLVIPVGATPYLQMLVRVRRVSEEEYRSEELCPVRFVPLIGAAGW
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase 1, L-isoaspartyl protein carboxyl methyltransferase 1, Protein L-isoaspartyl methyltransferase 1, Protein-beta-aspartate methyltransferase 1, PIMT 1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK33_AETCO
Sequence: MAKGKDVRVTIFLECTSCVRNDIKKEFAGISRYITQKNRHNTPSRLELRKFCPYCYKHTIHGEIKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CP310_DROME
Sequence: MWLLLPILLYSAVFLSVRHIYSHWRRRGFPSEKAGITWSFLQKAYRREFRHVEAICEAYQSGKDRLLGIYCFFRPVLLVRNVELAQTILQQSNGHFSELKWDYISGYRRFNLLEKLAPMFGTKRLSEMFGQVQKVGDHLIHHLLDRQGQGCPQEVDIQQKLRVYSVNIIANLIYGLDINNFEHEDHILTSYLSHSQASIQSFTLGRLPQKSSYTYRLRDLIKQSVELREDHGLIRKDILQLLVRFRNGNEVSGDKWQLEPINDADKLLSIKRLAKVAEDLLKVSLDAVASTVTFTLLEILQEPLIVEKLRAEIKELSNENGQLKFEELNGLRYMDMCLKETLRKYPPLPIIERVCRKSYSLPNSKFTIDEGKTLMVPLLAMHRDEKYFSEPMKYKPLRFLQTANDVGQCEDKTKSNVFIGFGIGGSQCVGQNFAKLVIKVALIKLLQNFHLELDANQVKTLKVSHRPAPFIHTKDGLKVKLKRREINTKFYS
What is the function of this protein?
May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
What are the official names of this protein?
Probable cytochrome P450 310a1, CYPCCCXA1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: TAM_RHIE6
Sequence: MAWSAQQYVKFEDERTRPARDLLAQVPLQSLRRAVDLGCGPGNSTELIIERFGAEGVSGLDSDVNMLEAARKRLPGTAFVEADLGSWQPTEPADLLFANAVFQWLPDHLDIFDRLMDGLSPGGVLAVQMPDNLGEASHLAMEESAHAGPWKAAFEEKSVRRQPLAPPSAYYSRLIGKAARIDIWHTIYNHPMADAADIVEWVKGTGLMPYLAHAGEAYREAFLADYLERIEKAYPKMSDGRVMLRFPRIFMVAVKK
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFD_ACTP2
Sequence: MFKMVSSPHTHSSNLTAKFMLWVMVAMLPALGMQAYFFGYGVFIQVFIALLLAVAIEIAIAKLRRKPTAFYVADLSGVLTALILAISIPPYAPYWIIVIGIIVALLLAKHSYGGLGQNLFNPAMVAYALLLVSFPVQMTGWLVPIDLLNEPPTFGDAISLVFSGVTSDGFSVHQLLGSVDGIAQATPLDSAKTSMQKLGVEGVLQSPIFSGLFANGWWQINLAFLAGGLLLIYKRIIHWQIPAAMLGMFALLSGLTDLLLPHTHLNVVSQLFSGAMMFGAFFIATDPVTASITPRGKLIFGGLIGLFVYLIRYYGNYPDAVAFSVLLANICVPLIDHYTQPRLYGSGR
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rnf electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MSH3_MAGO7
Sequence: MAGPSGAAPKKQASLLGFFTPKTVNGLKRPTSSRPGTSEEDEERTADSSPSSRDNVRKRPLEQDPDAGNTRRPRASKRAKNVVIDDEDDEHDNDDDDDDFKLDAEAEADPEPVVAADDTAGVSQSSSISASRAGRYIYDESQPKGQAKTDENGDALDAATLRKKRELHDKFVKKLGHPDAMSRWGNAGRGEQETGAQEEEEDGDAAEEEPPPPPKGKKKGAKSGKLTPMELQFLEIKRKHMDTVLIVEVGYKFRFFGEDARIAGKELSIVCIPGKFRYDEHPSEAHLDRFASASIPVHRLPVHAKRLVAAGHKVGVVRQIETAALKKAGDNRNAPFVRKLCEVYTKGTYIDEMGEMDAQTGASGAHSGGYLLCLTETAAKGSGTDEKVDVGLVAVQPATGDIIYDSFEDGFMRSEIETRLLHISPCELLIVGQLSKATEKLVKHLSGSASNVFGDRTRVERVAKGKTTPAEASSHVTKFYAGKLKGSTQDDRAAALLDKVLNLPEPVTLCLSAMITHLTEFGLEHIFDLTKYFQSFSTRSHMCINGTTLESLEVYRNSTDHTEKGSLLWALDKTRTRFGQRMLRKWLGRPLLDKERLDDRVAAVEELFENRNGPQVEKLQKLLSSIKTDLERSLIRIFYGRCTRPELLAVLQTLQRIAVEYIVVKEPSQTGFKSNLVSEALASLPRIREIVVSYLNRINPDAARKNDKYEFFRDESDDTGDDGEDEITTQKMSIAAVEQELDAHRSDAAATLGRKKAVDYVTVAGIEYLIEVPNTEIRKVPASWAKISGTKKLSRFHTPEVVRLIAERDQHKEALAAACDAAFKAMLASIADQYQPLRDAVSSLATLDCLLSFAQVAALPGYSKPIILPDSHPPTIAVAGGRHPIAEHTLPSGYIPFSTTLSSPAPLAHLVTGPNMGGKSSFVRALALLVLLAQVGSFVPADSLRLTLSDAIYTRMGASDNLFAGESTFMVEVGETAAILRTATPRSLVLLDELGRGTSTHDGAAIAHAVLDHVVRNTRCLTLFITHYQSLARVAEGLGTGLVRNVHMRFTSSRDDNDDGDKDQDDDVGENITFLYEVADGVAHRSYGLNVARLARIPRKILEVAARKSRKMEEDVRTRRLRSATKLLEAVCRGDGSDDQLEHLLSSIEQL
What is the function of this protein?
Component of the post-replicative DNA mismatch repair system (MMR).  Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair.  MSH3 provides substrate-binding and substrate specificity to the complex.  When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs.  Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication.  After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.  ATP binding and hydrolysis play a pivotal role in mismatch repair functions (By similarity).
What are the official names of this protein?
DNA mismatch repair protein MSH3, MutS protein homolog 3.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MSH3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPE_PARP8
Sequence: MATIKVDVVSAEEQIFSGQAKFVALPGEAGELGILPGHTPLITRIRPGAVRIESENGEEEFVFVAGGILEVQPGAVTVLADTAIRGKDLDEAKAEQARKRAEEALQNTGSNLEYATAQAELAYATAQLAAIQRLRKLRGQH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PGLRD_EMENI
Sequence: MKRCALLTPLLPLALACNNPNDPAHSCASIYSVSSDEAASFCATFTASVVSEPTGVPDAFLSACDSKIKHLSSACSCLGPVDSATATPVPATSTVPASVPVITTSTATATPSRIPVFVPSSSSSSAVVTFKTQIKSSSPGPSSSFAAAATTEAPTSTRASPYTPYTGNGGTTCTVTDYAGISSAVASCSNIMLSDVYAPPSSTIDLQDLQTGAAVIFAGKTTFGDTSDSDFDPIVISGTNLTITGTEDHVIDGNGQAYWDGQGSNGGSDKPDHFIVLKHVYNSVVANLNIQNWPVHCFDIENTESLTLTGITLDNSAGDEPNDSSDGDPAAHNSDGFDIKSSTDLILKDSNVYNQDDCVAITSGTNITVDNMYCSGGHGLSIGSIGGKSDNTVDGVVFSNSQVVNSQNGCRIKTNEGETGEVSNIKYENISLSGISKYGIVVQQDYLNGGPTGEPSNGVSITNVEFTDVTGTMSGGKDYYILCGDGSCENFTFSGVSITGGSDDSCNYPDSGCP
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.  Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall (By similarity).
What are the official names of this protein?
Probable endopolygalacturonase D, PGD, Pectinase D, Polygalacturonase D.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPH2_MYCTU
Sequence: MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANETLVFALPRELRSPR
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (PubMed:23091471).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.  Has a higher activity compared with LytB2 (PubMed:23091471).  Is essential for M. tuberculosis growth in vitro (PubMed:26309039).
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2, HDR 2, HMBPP reductase 2.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: PHSG_CHLPN
Sequence: MEDFSSFDKNKVSVDSMKRAILDRLYLSVVQSPESASPRDIFTAVAKTVMEWLAKGWLKTQNGYYKNDVKRVYYLSMEFLLGRSLKSNLLNLGILDLVRKALKTLNYDFDHLVEMESDAGLGNGGLGRLAACYLDSMATLAVPAYGYGIRYDYGIFDQRIVNGYQEEAPDEWLRYGNPWEICRGEYLYPVRFYGRVIHYTDSRGKQVADLVDTQEVLAMAYDIPIPGYGNDTVNSLRLWQAQSPRGFEFSYFNHGNYIQAIEDIALIENISRVLYPNDSITEGQELRLKQEYFLVSATIQDIIRRYTKTHICLDNLADKVVVQLNDTHPALGIAEMMHILVDREELPWDKAWEMTTVIFNYTNHTILPEALERWPLDLFSKLLPRHLEIIYEINSRWLEKVGSRYPKNDDKRRSLSIVEEGYQKRINMANLAVVGSAKVNGVSSFHSQLIKDTLFKEFYEFFPEKFINVTNGVTPRRWIALCNPRLSKLLNETIGDRYIIDLSHLSLIRSFAEDSGFRDHWKGVKLKNKQDLTSRIYNEVGEIVDPNSLFDCHIKRIHEYKRQLMNILRVIYVYNDLKENPNQDVVPTTVIFSGKAAPGYVMAKLIIKLINSVADVVNQDSRVNDKLKVLFLPNYRVSMAEHIIPGTDLSEQISTAGMEASGTGNMKFALNGALTIGTMDGANIEMAEHIGKENMFIFGLLEEQIVQLRREYCPQTICDKNPKIRQVLDLLEQGFFNSNDKDLFKPIVHRLLHEGDPFFVLADLESYIAAHENVNKLFKEPDSWTKISIYNTAGMGFFSSDRAIQDYARDIWHVPTKSCSGEGN
What is the function of this protein?
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism.  Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates.  However, all known phosphorylases share catalytic and structural properties (By similarity).
What are the official names of this protein?
Glycogen phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the glycogen phosphorylase family.
Protein: SMD3B_ARATH
Sequence: MSRSLGIPVKLLHEASGHIVTVELKSGELYRGSMIECEDNWNCQLEDITYTAKDGKVSQLEHVFIRGSKVRFMVIPDILKHAPMFKRLDARIKGKSSSLGVGRGRGAMRGKPAAGPGRGTGGRGAVPPVRR
What is the function of this protein?
Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity).  May play a major role in the splicing of cellular pre-mRNAs.  Required for normal plant development (PubMed:21421416).
What are the official names of this protein?
Small nuclear ribonucleoprotein SmD3b, SmD3-b, snRNP core protein D3-b.
What is the protein family that this protein belongs to?
Belongs to the snRNP core protein family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
Protein: ENGB_ANADF
Sequence: MPVQVVSSEFVKTATRPPEWPRGQTPELAFVGRSNVGKSSMLNALTRKKGLARVSATPGRTRALQFFDVAYRPTPAARPRHVRFCDLPGYGYAKVSREERDRWAAMIEDYLRDRDVLRAVVLIVDARHAPSDSDVDAAAFLRATGRRVLVAATKMDKLPKTRRGAALRAVEGALALAKGEAVPFSAVEGTGTDALWARIASAATDEGAPAPAGAGA
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RL24_ELUMP
Sequence: MLKKNDSVVILSGKDKGKKGEIKEVIASKNRVIVSGVNIVSKHEKPAGNKKGGIIKVEAPLHISNVAIVCKKCNKAMTPKHTVANDGAKVRVCRKCGETVK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RL16_MANSM
Sequence: MLQPKRTKFRKVHKGRNRGIAAGTDVSFGTYGLKAIGRGRLTARQIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLEVRMGKGKGNVEYWVALIQPGKVLYEMDGVSEEIAREAFALAAAKLPIKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RNC_PSEMY
Sequence: MSPNLSRLERKLGHSFKDQDLMILALTHRSFAGRNNERLEFLGDAILNFVAGEALFERFPQAREGQLSRLRARLVKGETLAVLARGFELGEYLRLGSGELKSGGFRRESILADALEALIGAIYLDAGMDAARERVLDWLSGELDGLTLIDTNKDPKTRLQEFLQSRACELPRYEVVDIQGEPHCRTFMVECQVALLNEKTLGQGGSRRIAEQVAAAAALIALGVENGND
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 5053R_ASFM2
Sequence: MSLQELCRKNLPDCELPEFFDDYVLQLLGLHWQDHGSLQRTGKNQVLVQQEPIHINEALKSAASEGNYEIVELLLSWEADPRYAVVGALESNYYDLVHKYYDQVKDCHDMLPLIQNPEMFEKCHELNNTCSLKCLFKHAVIHDMLPILQKYSDYLDGWQYCNQILFELACKRQKYNMVVWIEGVLGVGNFKILFTIAINNRDLQLYSLGYLIILERLYSCGQDPTFLLNHFLRDVSMKGLLPFVLKTIEFGGSKEIAITLAKKYQHKHILKYFETEEC
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 505-3R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 505 family.