PharMolix/UniProtQA huggingface dataset:
Protein: YL302_YEAST
Sequence: MRWHCMDGGNRIVSMYLTTLYYTKEIVDEKTREQEKGKTSFLTDALLNLIYILFFSSSVFNWTRCHLFDTSVIMLHSFHEDGALTNLISHLPTTTVPQYRQLHVPFAILRSCDLKRKSKK
What are the official names of this protein?
Uncharacterized protein YLR302C.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PGA11_CANAL
Sequence: MKFQFVTALALASTMAVAAPINDQQEVLGAVAATRSKREGGSTGAELQDNNQPTAGLFGDGNSFGNQGLGGFLAATVDSLTKTIASPIKGILAPGGGSGGNGGSGGSGAAGGVGNLFSGILGGL
What are the official names of this protein?
Predicted GPI-anchored protein 11.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: ISPDF_HELAH
Sequence: MSLIRVNGEAFNLSLESLKEDPFETKKTLETLIKQTSVILLAAGESRRFSQTIKKQWLRSNHTPLWLSVYESFTEALDFKEVILVVSELDYTYIKRHYPKIKLVRGGISRQESVCNALKVISGAYTLTSDVARGLANIEMLNDLFLTLQNTNHYCIAPYLPCYDTAIYYNEALDREAIKLIQTPQLSHTKTLQLALNQGDFKDESSAILQAFPDLVSYIEGSKDLHKLTTSDDLKIFTPFFNPAKDTFIGMGFDTHAFIKDKPMVLGGVVLDCEFGLKAHSDGDALLHAMIDAILGAIKGGDIGEWFPDNDPKYKNASSKELLKIVLDFSQSIGFELFEMGATIFSEIPKITPYKPAILENLSQLLGLEKSQISLKATTMEKMGFIGQQEGLLVQAHASMRYKQKL
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: DUT_RHIEC
Sequence: MTIHHDTPPTLNLIRLANGEGLDLPAYESKGAAGMDLRAAVDGDAPLTLAPGERALLPTGFIFEIPEGFEGQVRPRSGLAFKHGITCLNSPGTVDSDYRGEVKVLLANLGEEAFVIERGMRIAQMVIAPVTQARVTEIAAASETARGAGGFGSTGV
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: ILVD_ACIBS
Sequence: MPDYRSKTSTHGRNMAGARGLWRATGMKDEDFGKPIIAVVNSFTQFVPGHVHLKDLGQLVAAEIQAAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSRDLIADSVEYMVNAHCADAMVCISNCDKITPGMLMAAMRLNIPVVFVSGGPMEAGKVKFRGDEKAIDLVDAMVVAADDSYTDEEVAEFERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSIVATHANRKKLFLKAGQLIVELAKRYYEQNDASILPRSIATKAAFKNAMTLDIAMGGSTNTVLHLLAAANEAEVDFTMDDIDELSRRVPVLSKVAPAKQDVHMEDVHRAGGIMAILGELDRANLLDVSVPTVHEKTLKDALDKWDIIRTEDPDVYEFYRSSPGGVPTQVAFSQNRYYSTLDGDREKGVIRNAEHAFSKDGGLAVLYGNIALDGCIVKTAGVDESILKFTGSARVFESQDAAVEAILGNEIKAGDVVVIRYEGPRGGPGMQEMLYPTSYLKSKGLGKDCALVTDGRFSGGSSGLSIGHVSPEAAEGGAIGLVEDGDTIEIDIPNRTIHLNIDDATLAHRRTVQEAKGWHPKEERKRKVSKALKVYAMHTTSAAKGAVRVL
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: PLSB_ECO81
Sequence: MSGWPRIYYKLLNLPLSILVKSKSIPADPAPELGLDTSRPIMYVLPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGTLLPRYVFIHGGPRVFTYYTPKEESIKLFHDYLDLHRSNPNLDVQMVPVSVMFGRAPGREKGEVNPPLRMLNGVQKFFAVLWLGRDSFVRFSPSVSLRRMADEHGTDKTIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASRAIAKAVEDEARSKKISHEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWNRLYQGINVHNAERVRQLAHDGHELVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTIQAMLRGGTRPITLIPIYIGYEHVMEVGTYAKELRGATKEKESLPQMLRGLSKLRNLGQGYVNFGEPMPLMTYLNQHVPDWRESIDPIEAVRPAWLTPTVNNIAADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQLNCYLDLMRNVPYSTDSTVPSASASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLVLPSLMAAIVTQHRHISRDVLMEHVNVLYPMLKAELFLRWDRDELPDVIDALANEMQRQGLITLQDDELHINPAHSRTLQLLAAGARETLQRYAITFWLLSANPSINRGTLEKESRTVAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYISDSGDAEPAETMKVYQLLAELITSDVRLTIESATQGEG
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FOLD2_BORPA
Sequence: MKDKVIDGSRASARIREQLKERVACLRARNIRPGLAVLLVGEDPASQVYVRNKVAACEQVGIHSVTERYPSAWTENQLLDRIASLNGDPAINGILVQLPLPPHMSAHRVIEAISPLKDVDGFHISNAGLLMTGKPQFQPCTPYGVMKLLESEGVSLRGAEAVIVGASNIVGKPMAMLLLAAGATVTICNSKTRDLAGQARRADVLIVAAGRAGIVDGSMIKPGAVVIDVGINRGPDGRLCGDVDYGSAAKVAGAITPVPGGVGPMTIAMLLANTVEAAERSAI
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD 2.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: OPGG_ECOSM
Sequence: MKHKLQMMKMRWLSAAVMLTLYTSSSWAFSIDDVAKQAQSLAGKGYEAPKSNLPSVFRDMKYADYQQIQFNHDKAYWNNLKTPFKLEFYHQGMYFDTPVKINEVTATAVKRIKYSPDYFTFGDVQHDKDTVKDLGFAGFKVLYPINSKDKNDEIVSMLGASYFRVIGAGQVYGLSARGLAIDTALPSGEEFPRFKEFWIERPKPTDKRLTIYALLDSPRATGAYKFVVMPGRDTVVDVQSKIYLRDKVGKLGVAPLTSMFLFGPNQPSPANNYRPELHDSNGLSIHAGNGEWIWRPLNNPKHLAVSSFSMENPQGFGLLQRGRDFSRFEDLDDRYDLRPSAWVTPKGEWGKGSVELVEIPTNDETNDNIVAYWTPDQLPEPGKEMNFKYTITFSRDEDKLHAPDNAWVQQTRRSTGDVKQSNLIRQPDGTIAFVVDFTGAEMKKLPEDTPVTAQTSIGDNGEIVESTVRYNPVTKGWRLVMRVKVKDAKKTTEMRAALVNADQTLSETWSYQLPANE
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein G.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RS7_STRPB
Sequence: MSRKNQAPKREVLPDPLYNSKIVTRLINRVMLDGKRGTAATIVYYAFSAIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLRWLVNASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: SR1IP_DANRE
Sequence: MAAPGPNKDNIRAGCKRCGYPGHLTFECRNFLRVDPRKDIVLDVSSTSTEESDEEEQEALSKEKIFGSHSKGSQEDSRKEKHKKKSKERSRGKAKKRSYSSSDEEEDEMSKKKKKRKSNKKKGKKEKREKERKHKKKQKKKDTESSSSDSSSESSDTD
What is the function of this protein?
Possible splicing regulator involved in the control of cellular survival.
What are the official names of this protein?
Protein SREK1IP1.
Protein: RL33_METEP
Sequence: MAKAVTVKIRLVSTADTGYFYVTKKNSRTQTEKMVMKKYDPVARKHVEFKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RMD2_MACFA
Sequence: MPHSTNKELIFGIMVGTAGISLLLLWYHKVRKPEKTMKLPKFLSLDNTFNSITLQDEVHNDQGTTVIFQERQLQILEKLNELLTNMEELKEEIRFLKETVPKLEEYIQDELGGKITVHKVSPQHRARKRRLPTIQSSATSNSSEEAESEGGYITANTDTEEQSFPVPKAFNTHVEELNLDVLLQKVDHLRMSESGKSESFELLCDHKEKFRDKIEFMWRFARAYGDMYELSTNTQEKKHYANIGRTLSERAINRAPMNGHCHLWYAVLCGYVSEFEGLQNKINYGHLFKEHLDIAIKLLPEEPFLYYLKGRYCYTVSKLSWIEKKMAATLFGKIPSSTVQEALHNFLKAEELCPGYSNPNYMYLAKCYADLEENQNALKFCNLALLLPTVTKEDKEAQKEMQKIMTSLKR
What are the official names of this protein?
Regulator of microtubule dynamics protein 2, RMD-2, Protein FAM82A1.
What is the protein family that this protein belongs to?
Belongs to the RMDN family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=In interphase localizes in the cytoplasm, and during mitosis localizes to the spindle microtubules and spindle poles. Also detected as large dots in the perinuclear region (By similarity).
Protein: RL7_DESVM
Sequence: MSSITKEQVVEFIANMTVLELSEFIKELEEKFGVSAAAPAMAMVAAGPAEAAPAEEEKTEFDVILKAAGANKIGVIKVVRALTGLGLKEAKDKVDGAPSTLKEAVSKEEAEEAKKQLVEAGAEVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: EFTS_ANAMF
Sequence: MKVGVEAIRELRQITGAGLGDCKEALETCSGDMEKAKVYLREKGLSKAYKKSHRDAADGLVAVRVEGDKGAILKLGSETDFVARNEKFRSLAAELVSSLLKHGAEDLSSFSASPYDGGSGVSVADEVVNAAAVLGEHIVLSGIGFLELGGPGVIGSYIHGAVGEGIGRAGALVALEATTAKTEALLEFARQLAMHIVAAKPESVSVETLSNDIVEREREIVAKQVEALGKPESVASKIVDGRMQKFFEDMVLLEQTFIMDGSTKIRDLLHNKGQDLGCEVRIVAYRLFSVG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_RICCK
Sequence: MATKLIKHGSEAREEMLKGVDILANAVKVTLGPKGRNVLIEQSFGAPKITKDGVTVAKSIELKEKIRNAGAQLLKSAATKAAEVAGDGTTTATVLARALAREGNKLVAAGYNPMDLKRGMDLAVNTVVEEIKKSSKKINSQEEIAQVGTISSNGDKEIGEKIAKAMEEVGKEGVITVEEAKNFSFDVEVVKGMMFDRGYLSPYFVTNSEKMVAELENPFILLFEKKLSNLQPMLPILEAVVQSQRPLLIIAEDVEGEALATLVVNRLRGGLKVAAVKAPGFGDRRKAMMEDIAILTKGELITEDLGMKLENVSIKSLGTAKRVTISKENTVIVDGSGDKKSIEDRVLQIKSQIAETTSDYDKEKLQERLAKLSGGVAVLKVGGATEVEVKERKDRVEDALAATRAAVEEGVVAGGGVTLLHTSQILTKLKVENKDQQAGIEIVIEALKDPLKQIVENAGENGGVVVGKLLEHKDKNFGFNAQDMQYVDMIQAGIIDPAKVVRTALQDAASVASLIITTETLIVDEPSKEEPMPMRGSGMGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RCCD1_MOUSE
Sequence: MAEKRHGAWFGFGFCGFGQALGSGNSHHSVYSPEPLHASDDICQVSAGWSYTALVTRGGRVELSGSVSGAADGCRDVWASEELLVLLRNKGGSSTEVQAWVPGSALQGEPLWVQNLVSGAKGQGEDEPSRESRMGTLPLLPCARAYVTPEPPFCQPLAPELRVRQLELGAEHVLLLCAAGQVFSWGAGRHGQLGHGTLEAELEPRLLEALQGLRMAKVAAGGWHSVCLSETGDIYIWGWNESGQLALPTRSGTENKAEREEATELNEDGLKEELAVADAGAPAHFIAIQPFPALLDLPLGSDAVMASCGSRHTAVVTRTGELYTWGWGKYGQLGHKDSTSLDRPCCVEYFVERQLEVRAVTCGPWNTYVYAMERDKS
What is the function of this protein?
Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8.  Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation.  Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8.
What are the official names of this protein?
RCC1 domain-containing protein 1.
What are the subcellular locations of this protein?
Chromosome. Note=Colocalizes with trimethylated 'Lys-9' of histone H3 (H3K9me3).
Protein: DUS14_HUMAN
Sequence: MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGIVPDVYEKESRHLMPYWGI
What is the function of this protein?
Involved in the inactivation of MAP kinases.  Dephosphorylates ERK, JNK and p38 MAP-kinases.
What are the official names of this protein?
Dual specificity protein phosphatase 14, MKP-1-like protein tyrosine phosphatase, MKP-L, Mitogen-activated protein kinase phosphatase 6, MAP kinase phosphatase 6, MKP-6.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Protein: O16D_CONLI
Sequence: VLIIAVLFLTACQLTTAETYPRGQQRHHALRSTDKNSKLTRGCTPRNGACGYHSHCCSNFCHTWANVCL
What are the official names of this protein?
Conotoxin LvVID.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CH102_RHILO
Sequence: MTFRPLHDRILVRRIEAEEKTAGGIIIPDTAKEKPQEGEVIAIGPGARDESGKLTPLDVKAGDRILFGKWSGTEIKLNGEDLLIMKESDVMGVIEQTATVKKAA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES 2, 10 kDa chaperonin 2, Chaperonin-10 2, Cpn10 2.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COG3_CHIOP
Sequence: IVGGTEVTPGEIPYQLSLQD
What is the function of this protein?
This enzyme is a serine protease capable of degrading the native triple helix of collagen.
What are the official names of this protein?
Collagenolytic protease 36 kDa.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: MCRB_METTM
Sequence: MAKFEDKVDLYDDRGNLVEEQVPLEALSPLRNPAIKSIVQGIKRTVAVNLEGIENALKTAKVGGPACKIMGRELDLDIVGNAESIAAAAKEMIQVTEDDDTNVELLGGGKRALVQVPSARFDVAAEYSAAPLVTATAFVQAIINEFDVSMYDANMVKAAVLGRYPQSVEYMGANIATMLDIPQKLEGPGYALRNIMVNHVVAATLKNTLQAAALSTILEQTAMFEMGDAVGAFERMHLLGLAYQGMNADNLVFDLVKANGKEGTVGSVIADLVERALEDGVIKVEKELTDYKVYGTDDLAMWNAYAAAGLMAATMVNQGAARAAQGVSSTLLYYNDLIEFETGLPSVDFGKVEGTAVGFSFFSHSIYGGGGPGIFNGNHIVTRHSKGFAIPCVAAAMALDAGTQMFSPEATSGLIKEVFSQVDEFREPLKYVVEAAAEIKNEI
What is the function of this protein?
Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2-(methylthio)ethanesulfonate) using coenzyme B (CoB or 7-mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB).  This is the final step in methanogenesis (PubMed:2269306, PubMed:3350018).  Neither N-6-mercaptohexanoylthreonine phosphate (H-S-HxoTP) nor N-8-mercaptooctanoylthreonine phosphate (H-SOcoTP) nor any other thiol compound such as CoA or CoM can substitute for CoB as the electron donor (PubMed:3350018).
What are the official names of this protein?
Methyl-coenzyme M reductase I subunit beta, MCR I beta, Coenzyme-B sulfoethylthiotransferase beta.
What is the protein family that this protein belongs to?
Belongs to the methyl-coenzyme M reductase beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Under growth limiting conditions on nickel-depleted media, a fraction of 70% of the enzyme is localized close to the cytoplasmic membrane, which implies 'facultative' membrane association of the enzyme.
Protein: FABZ_KLEP7
Sequence: MTTDTHTLHIEEILELLPHRYPFLLVDRVLDFEEGRFLRAVKNVSVNEPFFQGHFPGKPILPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK_SYNFM
Sequence: MRHIAVVYKRMRPEAARLAQDIKSWLAKRNVLVFCMENIDSAGVLSSHQRVDFPQDTDLVIVLGGDGTLLSVARLIESRKIPVIGVNLGGMGFLTGITIDNCYMELERILGGDYEIEERMRLRVLVRREHREIFSHRVLNDAVINKGALARIIDLVTVIDGRFLTHYRGDGLIFSTPTGSTAYNLAAGGPIVFPTAQAIIITPICSFTLTNRPIIFPSHVIIRIELGEPIKDVTLTCDGQVGCLLAPSDRIVITAAANPLRLIKTPTVDHFEILRNKLKWGQA
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CORA_HAEIN
Sequence: MINAFAINDSRLVRIDEDQTDLNTAIWLDLLEPTGEEREMLQEGLGQSLASFLELEDIEASARFFEDEDGLHLHSFFYCEDEDNYADLASVAFTIRDGRLFTLRDRELPAFRLYRMRSRSQRLLECNSYEVLLDLFETKIEQLADVIENIYADLEELSRVILNGKQDEAFDEALNTLTEQEDTSSKVRLCLMDTQRALGFLVRKTRLPTNQLEQAREILRDIESLQPHNESLFQKVNFLMQAAMGYINIEQNKIMKFFSVVSVMFLPATLVASTYGMNFDFMPELHFKYGYPMAIGLMIAAALTPYIYFRRKGWL
What is the function of this protein?
Mediates influx of magnesium ions (By similarity).  Alternates between open and closed states.  Activated by low cytoplasmic Mg(2+) levels.  Inactive when cytoplasmic Mg(2+) levels are high (By similarity).
What are the official names of this protein?
Magnesium transport protein CorA.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MENH_SALPC
Sequence: MMLHAQHMPGQPGAPSLVFLHGFSGDCREWQPVGEQFHGCSRLYIDLPGHGGSAAIPVGRFADVIRLLRATLISYNILKFWLVGYSLGGRVAMMAACQGIPGLCGLVVEGGHPGLQNEQARAERRLSDGRWAERFRREPLTEVFHDWYQQPVFASLTAQQRQALTALRSQNNGETLAAMLEATSLAAQPDLREALNALAFPFYYLCGERDSKFRALAQEVAATCHVIRNAGHNAHRENPAGVVDSLAQILRL
What is the function of this protein?
Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
What are the official names of this protein?
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, SHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MenH family.
Protein: YA056_YEAST
Sequence: MLTIYKREAVVVQLLRPCYKLTLVHYVNTTQQRTDVVKSTTAAVSTNFRGCSNMRSIMRSNGLGDSLSLWKVVCRFPSLLFMNLRSVGPSEPLNARSLISQVLFPIICASVTFLPT
What are the official names of this protein?
Putative uncharacterized protein YAL056C-A.
Protein: RS3_SALSV
Sequence: MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLTKELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQINIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPEKPAAQPKKQQRKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: GPSB_BACCQ
Sequence: MISDKIKLTAKDILEKEFKTGMRGYQQEEVDKFLDMIIKDYEAFHKEFEQLKQQNARLKRELEEQKLAATQVPQQPVVQTPVAQPVYNNTNTDILKRLSNLEKAVFGSKLYE
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: ECOT_ECOL6
Sequence: MKTILPAVLFAAFATTSAWAAESVQPLEKIAPYPQAEKGMKRQVIQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLESKTLEGWGYDYYVFDKVSSPVSTMMACPDGKKEKKFVTAYLGDAGMLRYNSKLPIVVYTPDNVDVKYRVWKAEEKIDNAVVR
What is the function of this protein?
General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
What are the official names of this protein?
Ecotin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I11 (ecotin) family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL27_PHOV8
Sequence: MAHKKGVGSSKNGRESASKRLGVKIFGGQACKAGNIIVRQRGTEFHPGENIGMGRDHTLFALVDGTVCFKVGRNDRRSVSVVPAVEA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: KRCC1_BOVIN
Sequence: MKHSKKTYDSFQDELEDYIKVQKARGLEPKTCFRKMREDYLETYGYKEEVDSRPRCRMFEQRLPYGTVQTYPRSCSISQRVEKQLPQWLPAHDSRLRLDSLSYSQFTRDCFSGKPVPPNLSQHESNCSSYSVESGVYRHLSSENNTSAHQASYKHIHQKRKRHTEEGREKPEEERPKHKRKKACEEIDLDKYKSIQTSKTEAETVRVSTEKLKNRKEKRSRDVASKKEERKRRKEKKEQGQERTEEEMLWDQSILGF
What are the official names of this protein?
Lysine-rich coiled-coil protein 1.
Protein: RECA_STRPS
Sequence: MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGERAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGIAAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVAALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGNPETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAVVEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFDEIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.