PharMolix/UniProtQA huggingface dataset:
Protein: SBCC_PSEAE
Sequence: MKILAIRLKNLASLAGEQEIDFTREPLSSAGLFAITGPTGAGKSTVLDALCLALFGSTPRLESTSASSKVPDGRNELSSNDERNLLRRGCASGYAEVDFVGIDGHRYRARWETRRSRDKADGALQKSQQSLQDLETQQMLAANKKSEFREQLEQKLGLNFAQFTRAVLLAQSEFSAFLKASDNDRGALLEKLTDTGLYSQLSKAAYQRASQADEQRKQLEQRLEGSLPLAEQARAGLEAALESHAQARLQEQQALQRLEGQQQWFTEEQRLLQSCEHAQGQLAEARQAWDALATERETLQWLERLAPVRGLIERLKQLEQELRHSEQQQRQRTEQQAAGTERLQGLQARLQEARERQAQADNHLRQAQAPLREAFQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAALGDAWVTHQGQLATFVQRRQRALESQAQLPELEKSLAHAGEPLERLQAQWTALHGSEPDDLAARLVELRRQTDSLERQQALHKEWQQVLDQRAGLARRLGELDQRMVEQEQALLDLKRQGSQCAEEVKAAEQALQVTRELLQRQRLARSASVEQLRAGLVDGEACPVCGSQEHPYHHSEQLLAALGEHDDQEQVRAEQSLERLRQTLVGLREGYSSQRERLNQSRQEQQELTGQLAALDRQLDQWTLPEELRLLQPSAQLEWLAQRLDDLAGQRQQCQRDFDRLIARQRQTQQLQQELRAAETILQQRQQALTEQRQRYEHLQQQVEEDSQQLRPLLSDEHWQRWQADPLRTFQALGESIEQRRQQQARLQQIEQRLQELKQRCDESSWQLKQSDEQRNEARQAEERAQAELAELNGRLGAHLGQHACAQDWQLSLEHAAQAAQSAVETLQAPLDSLREEQLRLAEALEHLQQQRQRQQDEFQRLQADWQAWRERQDNLDDSRLDALLGLSEEQATQWREQLQRLQEEITRQQTLEAERQAQLLQHRRQRPETDREALEDNLRQQRERLAASEQAYLETYSQLQADNQRREQSQALLAELERARAEFRRWGRLNELIGSSSGDKFRRIAQGYNLDLLVQHSNVQLRQLARRYRLQRGGSELGLLVVDTEMGDELRSVYSLSGGETFLISLALALGLASMASSKLRIESLFIDEGFGSLDPESLQLAMDALDNLQAQGRKVAVISHVQEMHERIPVQVRVQREGNGMSSLKVVG
What is the function of this protein?
SbcCD cleaves DNA hairpin structures.  These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions.  The complex acts as a 3'->5' double strand exonuclease that can open hairpins.  It also has a 5' single-strand endonuclease activity (By similarity).
What are the official names of this protein?
Nuclease SbcCD subunit C.
What is the protein family that this protein belongs to?
Belongs to the SMC family. SbcC subfamily.
Protein: NDUS2_PONPY
Sequence: MAALRALGGLRGVAAQVLRPGAGVRLPIQPSRGVRQWQPDVEWAQQFGGAVMYPSKETAHWKPPPWNDVEPPKDTIVKNMTLNFGPQHPAAHGVLRLVMELSGEMVRKCDPHIGLLHRGTEKLIEYKTYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIRPPPRAQWIRVLFGEITRLLNHIMAVTTHALDLGAMTPFFWLFEEREKMFEFYERVSGARMHAAYIRPGGVHQDLPLGLMDDIYQFSKNFSLRLDELEELLTNNRIWRNRTIDIGVVTAEEALNYGFSGVMLRGSGIQWDLRKTQPYDVYDQVEFDVPVGSRGDCYDRYLCRVEEMRQSLRIIAQCLNKMPPGEIKVDDAKVSPPKRAEMKTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPYRCKIKAPGFAHLASLDKMSKGHMLADVVAIIGTQDIVFGEVDR
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (By similarity).  Essential for the catalytic activity and assembly of complex I (By similarity).  Redox-sensitive, critical component of the oxygen-sensing pathway in the pulmonary vasculature which plays a key role in acute pulmonary oxygen-sensing and hypoxic pulmonary vasoconstriction (By similarity).  Plays an important role in carotid body sensing of hypoxia (By similarity).  Essential for glia-like neural stem and progenitor cell proliferation, differentiation and subsequent oligodendrocyte or neuronal maturation (By similarity).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial, Complex I-49kD, CI-49kD, NADH-ubiquinone oxidoreductase 49 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: LFC_CARRO
Sequence: MVLASFLVSGLVLGLLAQKMRPVQSKGVDLGLCDETRFECKCGDPGYVFNIPVKQCTYFYRWRPYCKPCDDLEAKDICPKYKRCQECKAGLDSCVTCPPNKYGTWCSGECQCKNGGICDQRTGACACRDRYEGVHCEILKGCPLLPSDSQVQEVRNPPDNPQTIDYSCSPGFKLKGMARISCLPNGQWSNFPPKCIRECAMVSSPEHGKVNALSGDMIEGATLRFSCDSPYYLIGQETLTCQGNGQWNGQIPQCKNLVFCPDLDPVNHAEHKVKIGVEQKYGQFPQGTEVTYTCSGNYFLMGFDTLKCNPDGSWSGSQPSCVKVADREVDCDSKAVDFLDDVGEPVRIHCPAGCSLTAGTVWGTAIYHELSSVCRAAIHAGKLPNSGGAVHVVNNGPYSDFLGSDLNGIKSEELKSLARSFRFDYVRSSTAGKSGCPDGWFEVDENCVYVTSKQRAWERAQGVCTNMAARLAVLDKDVIPNSLTETLRGKGLTTTWIGLHRLDAEKPFIWELMDRSNVVLNDNLTFWASGEPGNETNCVYMDIQDQLQSVWKTKSCFQPSSFACMMDLSDRNKAKCDDPGSLENGHATLHGQSIDGFYAGSSIRYSCEVLHYLSGTETVTCTTNGTWSAPKPRCIKVITCQNPPVPSYGSVEIKPPSRTNSISRVGSPFLRLPRLPLPLARAAKPPPKPRSSQPSTVDLASKVKLPEGHYRVGSRAIYTCESRYYELLGSQGRRCDSNGNWSGRPASCIPVCGRSDSPRSPFIWNGNSTEIGQWPWQAGISRWLADHNMWFLQCGGSLLNEKWIVTAAHCVTYSATAEIIDPNQFKMYLGKYYRDDSRDDDYVQVREALEIHVNPNYDPGNLNFDIALIQLKTPVTLTTRVQPICLPTDITTREHLKEGTLAVVTGWGLNENNTYSETIQQAVLPVVAASTCEEGYKEADLPLTVTENMFCAGYKKGRYDACSGDSGGPLVFADDSRTERRWVLEGIVSWGSPSGCGKANQYGGFTKVNVFLSWIRQFI
What is the function of this protein?
This enzyme is closely associated with an endotoxin-sensitive hemolymph coagulation system which may play important roles in both hemostasis and host defense mechanisms.  Its active form catalyzes the activation of factor B.
What are the official names of this protein?
Limulus clotting factor C, FC.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in hemolymph.
Protein: CBHA_ASPTN
Sequence: MHQRALLFSALVGAVRAQQAGTLTEEVHPPLTWQKCTADGSCTEQSGSVVIDSNWRWLHSTNGSTNCYTGNTWDESLCPDNEACAANCALDGADYESTYGITTSGDALTLTFVTGENVGSRVYLMAEDDESYQTFDLVGNEFTFDVDVSNLPCGLNGALYFTSMDADGGVSKYPANKAGAKYGTGYCDSQCPRDLKFINGMANVEGWTPSDNDKNAGVGGHGSCCPELDIWEANSISSAFTPHPCDDLGQTMCSGDDCGGTYSETRYAGTCDPDGCDFNAYRMGNTSYYGPDKIVDTNSVMTVVTQFIGDGGSLSEIKRLYVQNGKVIANAQSNVDGVTGNSITSDFCTAQKTAFGDQDIFSKHGGLSGMGDAMSAMVLILSIWDDHNSSMMWLDSTYPEDADASEPGVARGTCEHGVGDPETVESQHPGATVTFSKIKFGPIGSTYSSNSTA
What is the function of this protein?
The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
What are the official names of this protein?
Probable 1,4-beta-D-glucan cellobiohydrolase A, Beta-glucancellobiohydrolase A, Cellobiohydrolase D, Exocellobiohydrolase A, Exoglucanase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 7 (cellulase C) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS2_CUPNH
Sequence: MSVTMREMLEAGCHFGHQTRFWNPKMAPFIFGHRNKIHIINLEKTLPMFQDAMKYVRQLAANRGTILFVGTKRQSREILAEEAGRAGMPYVDARWLGGMLTNFKTVKTSIKRLKDMEAAKEAGALETMSKKEALMFEREMLKLEKSIGGIKDMGGVPDAIFVVDVGYHKIAVTEANKLGVPVIGVVDTNHSPEGIDYVIPGNDDSSKAVALYVRGVADAILEGRANAVQEVVEAARGGDDEFVEVQEG
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: SFSA_ESCF3
Sequence: MQFFPPLQRATLIQRYKRFLADVITPDGRELTLHCPNTGAMTGCATPGDTVWYSTSENTKRKYPHTWELTETQAGALICVNTLWANRLTKEALENDWLSELSGYSELRSEVKYGAERSRIDFMLQAGFQPDCYIEVKSVTLADHGQGYFPDAITQRGQKHLRELMSVAAEGQRAVILFAVLHSAITRFSPARHIDMKYAQLLTEAQQRGVEILAYKAEISAEGMSLKKLLPITL
What is the function of this protein?
Binds to DNA non-specifically.  Could be a regulatory factor involved in maltose metabolism.
What are the official names of this protein?
Sugar fermentation stimulation protein A.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: HIS4_CLOBK
Sequence: MIILPAIDLKEGKCVRLYQGDFKASKVVAEDPIEVALKFKENGAEYIHIVDLDGALTGQIKNLSIISSIIKTINIPVELGGGIRNLNTIDMLIDAGIERVILGTAALNNRGLVEKAVKKYDKKIAIGIDAKNEKVAINGWLNISSTNYIDFAKEMEKIGIRNIIFTDISKDGTLKGPNLNQLKKLNESVSCNIIASGGIKDIEDLKVIKEMDIYGAIVGKAIYSGNIDLNEAIKIINKESSR
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG8_PICST
Sequence: MRSQFKDEHPFEKRQAEATRIAQRFKDRVPVICEKVENSDIPEIDKRKYLVPVDLSVGQFVYVIRKRIKLPSEKAIFIFVNDILPPTAALISTIYEEHKDEDGFLYVLYSGENTFGQKKPLDLSTIDWSDLSDLDLAQK
What is the function of this protein?
Ubiquitin-like modifier involved in autophagosomes formation.  With ATG4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Participates also in membrane fusion events that take place in the early secretory pathway.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.
What are the official names of this protein?
Autophagy-related protein 8, Autophagy-related ubiquitin-like modifier ATG8.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Vacuole membrane; Lipid-anchor.
Protein: TF2B_METB6
Sequence: MQEVEKLKLLQSEREALKSRIKVKEQEKKAENHTETVCPECGGRQLVHDYERAELVCQSCGLVIDDDFIDRGPEWRAFDHDQRMKRSRVGAPMTFTIHDKGLSTMIDWRNRDSYGRAISSKNRAQLYRLRKWQRRIRVSNATERNLAFALSELDRMASALGLPRNVRETAAVVYRDAVDKNLIRGRSIEGVAAAALYAACRQCSVPRTLDEIAEVSRVSRKEIGRTYRFISRELGLKLLPTSPIDYVPRFCSGLTLKGEVQSRAVEILRQAGERELTSGRGPTGVAAAAIYISSILGGERRTQREVAEVAGVTEVTIRNRYKELAEKLDIEIIL
What is the function of this protein?
Stabilizes TBP binding to an archaeal box-A promoter.  Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
What are the official names of this protein?
Transcription initiation factor IIB, TFIIB.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
Protein: ATPB1_ALBFT
Sequence: MAQDTQTNTAVQGKIVQCIGAVVDVEFPRDQMPKIYDALKLEGSALTLEVQQQLGDGIVRTIALGSSDGLRRGLMVSNTANPIMVPVGTATLGRIMDVLGTPIDERGPVSTEKYASIHRKAPTYDELSPSQELLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKAHSGLSVFAGVGERTREGNDFYHEMADSGVVNLENLGESKVAMVYGQMNEPPGNRLRVALTGLTIAESFRDEGKDVLFFVDNIYRFTLAGTEVSALLGRMPSAVGYQPTLAEEMGRLQERITSTKVGSITSIQAVYVPADDLTDPSPATTFAHLDSTVVLSRDIASLGIYPAVDPLDSTSRQLDPNVVGQDHYETARAVQGTLQRYKELRDIIAILGMDELAPEDKLTVARARKIQRFLSQPFHVAEVFTGSPGKYVSLAETIRGFKMIVAGECDHLPEQAFYMVGTIDEAFEKAKKI
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta 1, ATP synthase F1 sector subunit beta 1, F-ATPase subunit beta 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y5847_STRAW
Sequence: MIRFEDVSVTYDGAAEPTVRGVDFTVPEGELVLLVGPSGVGKSTVLGAVSGLVPHFTGGTLRGRVTVAGRDTRTHKPRELADVVGTVGQDPLSHFVTDTVEDELAYGMESLGIAPDVMRRRVEETLDLLGLAELRDRPISTLSGGQQQRVAIGSVLTPHPKVLVLDEPTSALDPAAAEEVLAVLQRLVHDLGTTVLMAEHRLERVVQYADRVALLPAPGAPLTLGTPPEVMAASPVYPPVVDLGRLAGWSPLPLTVRDARRRAGALRERLAATETPTPTATATATAAPAPSPSRPRRPRLLRKRAPVPSAALPVAAVEALAVRRGRVEALRRVDLTASPGEIIALMGRNGAGKSTLLGALVGLVPPAGGSVRVGGAVPHRTAPRDLVRRVGLVPQEPRDLLYADTVAAECVAADGDAGAEPGTCRALVSELLPGVADGTHPRDLSEGQRLALALAVVLTARPPLLLLDEPTRGLDYAAKGRLVTLLRALAADGHAIVLATHDVELAAELAHRVVILAAGEVVADGPTAEVVVASPSFAPQVTKILAPQHWLTVTQVREALA
What is the function of this protein?
Probably part of an ABC transporter complex.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative ABC transporter ATP-binding protein SAV_5847.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NPL41_ARATH
Sequence: MTMLRVRSRDGLERVSVDGPHITVSQLKTLIQDQLQIPIHNQTLSTNRNLLLAKSPSDFLAFTDMADPNLRISSLNLAHGSMVYLAYEGERTIRGGPAVTPAGSFGRKMTVEDLIARQMRVGRQEKAHCDSVSFDRDCANAFQHFVNESLAFAVKRGGFMYGNVSEDGQVEVNFIYEPPQQGMEDNLILMRDSEEEKRVDAIALGLGMRRVGFIFNQTVTQDKKEYTLSNVEVLLAAQLHAESELKEWVTAVVKLEINEDGGADVHFEPFQMSDMCVRLFKEGWFETEIGPEDDPKLSKLKKEVVVGVKDVKEVDNDFFLVLVKILDHQGPLSCTFPIENRNTQTTMRALKTHMERARSLPFVKRISDFHLLLFVAQFLDVSSDVPALAECVRLQSHVPEGYELLIDSMANTS
What is the function of this protein?
May be part of a complex that binds ubiquitinated proteins and that is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome.
What are the official names of this protein?
NPL4-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the NPL4 family.
Protein: ZNF3_HUMAN
Sequence: METQADLVSQEPQALLDSALPSKVPAFSDKDSLGDEMLAAALLKAKSQELVTFEDVAVYFIRKEWKRLEPAQRDLYRDVMLENYGNVFSLDRETRTENDQEISEDTRSHGVLLGRFQKDISQGLKFKEAYEREVSLKRPLGNSPGERLNRKMPDFGQVTVEEKLTPRGERSEKYNDFGNSFTVNSNLISHQRLPVGDRPHKCDECSKSFNRTSDLIQHQRIHTGEKPYECNECGKAFSQSSHLIQHQRIHTGEKPYECSDCGKTFSCSSALILHRRIHTGEKPYECNECGKTFSWSSTLTHHQRIHTGEKPYACNECGKAFSRSSTLIHHQRIHTGEKPYECNECGKAFSQSSHLYQHQRIHTGEKPYECMECGGKFTYSSGLIQHQRIHTGENPYECSECGKAFRYSSALVRHQRIHTGEKPLNGIGMSKSSLRVTTELNIREST
What is the function of this protein?
Involved in cell differentiation and/or proliferation.
What are the official names of this protein?
Zinc finger protein 3, Zinc finger protein HF.12, Zinc finger protein HZF3.1, Zinc finger protein KOX25.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CH603_RHIME
Sequence: MSAKQIVFSTDARDRLLRGVELLNNAVKVTLGPKGRNVVIDKSYGAPRITKDGVSVAKEIELEDKFENMGAQMVRAVASKTNDLAGDGTTTATVLAASIFREGAKLVSVGMNPMDLKRGIDLGVAAVLAEIKARATKVISSSEIAQVGTIAANGDAGVGEMIARAMEKVGNEGVITVEEARTADTELDVVEGMQFDRGYLSPYFVTNAEKMRVELEDPYILIHEKKLGSLQAMLPILEAAVQSGKPLLIISEDVEGEVLATLVVNRLRGGLKIAAVKTPGFGDRRKAMLEDIAVLTAGQMISEDLGIKLENVTLDMLGRARRVLIEKDTTTIIDGSGDKASIQARVSQIKAQIEETASDYDKEKLQERLAKLAGGVAVIRVGGATELEVKEKKDRIDDALNATRAAVEEGIVPGGGVALLRAKSALVGLTDDNADVTAGISIVRRALEAPIRQIADNAGVEGSIVVGKLVDGRDHNQGFDAQTETYVDMIKAGIVDPAKVVRTALRDAGSIASLLITAEAMIADIPERGSPQSTGNGAVDSMGY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 3, 60 kDa chaperonin 3, Chaperonin-60 3, Cpn60 3.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WFKN2_BOVIN
Sequence: MWALRGCRSGSRWGQGAALLLLLLGVPPRGLALPPLRYSHAGICPNDMNPNLWVDAQSTCKRECETDQECETYEKCCPNVCGTKSCVAARYMDVKGKKGPVGMPKEATCDHFMCLQQGSECDIWDGQPVCKCRDRCEKEPSFTCASDGLTYYNRCYMDAEACSKGITLAVVTCRYHFTWPNTSPSPPETTVHPTTAPPETPGLDATAPALLNHPAHQSVTVGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQPQDAGIYTCTARNAAGVLRADFPLSVVSGGQASATAESSPNGTALPAAECLKPPDSDDCGEEQTRWYFDAQANNCLTFTFGHCHRNRNHFETYEACMLACMSGSLAMCSLPALQGPCKAYVPRWAYNSQTGQCQSFVYGGCEGNGNNFESREDCEESCPFPRGNQRCRACKPRQKLVTSFCRSDFVILGRISELTEEPDSGRALVTVDEVLKDEKMGLKFLGQEPLEVTLLHMDWTCPCPNVTVGEAPLIIMGEVDGGMAVLRPDSFVGASSTRRARKLREVMHKKTCDVLKDFPGLQ
What is the function of this protein?
Protease-inhibitor that contains multiple distinct protease inhibitor domains.  Probably has serine protease- and metalloprotease-inhibitor activity.  Inhibits the biological activity of mature myostatin, but not activin (By similarity).
What are the official names of this protein?
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the WFIKKN family.
What are the subcellular locations of this protein?
Secreted.
Protein: RECX_CLOPE
Sequence: MGKITSIEVQKRNVNRVNVYVDEAFTFACDAELIYKQGIQKDSIIDIEAIKEIVKEDEFIKCKNSALRTVEKTYKTEKELRDKLAEKGFEEDTIKRAIEFLKEYNLLNDEKYAEMYIKDRLRSQGRNKIKYALIRKGVSEDILLDKLSNIDTEDENDTAFKLAEKKYNILKKKESDKYKLSQKLFRFLLSKGYDYDCCNSIVRRLTNNEYME
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PMT4_ARATH
Sequence: MKVASVIGLRPRISGLLFLTLGVIALITILVPNSDSSSTTSTTRVPPSNIYSNYGRVKEQAAVDYLDLRFFSLGVNRLKEFPLCGKERDNYVPCYNVTESDRNCEFAREEERCLVRPPRDYKIPLRWPVGRDIIWTGNVKITKDQFLSSGTMTKRLMLLEENQITFHSDDGLIFDGVKDYAFQIAEMIGLGSDTEFPQAGIRTVLDIGCGFGSFGAHLVSLNVMPICIAEYETSGSQVQLALERGLPAMIGNFFSKQLPYPALSFDMVHCAQCGITWDIKDAMLLLEVDRVLKPGGYFVLTSPTSKAQGNSPDTKKTSISTRVDELSKKICWSLSGQQDETFLWQKTADPNCYSSRSQASIPVCKDDDSVPYYHPLVPCISGTKSKRWIPIQNRSRASGTSLSELEIHGIKPEEFDEDIQVWRSALKNYWSLLTPLIFSDHPKRPGDEDPVPPFYMIRNAMDMNARYGNLNQALLNQGKSVWVMNVVPVKARNTLPIILDRGFTGALHDWCEPFPTYPRTYDMLHANELLTHLSSERCSLMDLFLEMDRILRPEGWVVLSDKLGVIEMARTLAARVRWEARVIDIQDGSDQRLLVCQKPLLKK
What are the official names of this protein?
Probable methyltransferase PMT4.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: CLPX_SYNE7
Sequence: MSRYDSHLKCSFCGKSQEQVRKLIAGPGVYICDECVDLCNEILDEELFDGNANPAPPPGSPKPATAATTSHQGPRKPKRSLTLSQIPKPHDIKRYLDHHVIGQNEAKKMLSVAVYNHYKRLAYQQSAEEAGETIEIQKSNILLIGPTGCGKTLLAQTLAKLLDVPFAVADATTLTEAGYVGEDVENILLRLLQVADLDIEEAQRGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKMLEGTIANVPPQGGRKHPYQDCIQIDTRNILFICGGAFVGLEKLVDRRLGKKSIGFVHPEESKTKEQRAAAILRHMEPEDLVQFGLIPEFIGRMPVTAVLDPLDETALTEILTEPRDALVKQYQKLMHMDSVELEFRQDAIEAIAREAFRRKTGARALRGIVEEIMLEVMYELPSRQDVTHCTITREMVEKRSSADVLLLPSSLPTPESA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: PDE3B_HUMAN
Sequence: MRRDERDAKAMRSLQPPDGAGSPPESLRNGYVKSCVSPLRQDPPRGFFFHLCRFCNVELRPPPASPQQPRRCSPFCRARLSLGALAAFVLALLLGAEPESWAAGAAWLRTLLSVCSHSLSPLFSIACAFFFLTCFLTRTKRGPGPGRSCGSWWLLALPACCYLGDFLVWQWWSWPWGDGDAGSAAPHTPPEAAAGRLLLVLSCVGLLLTLAHPLRLRHCVLVLLLASFVWWVSFTSLGSLPSALRPLLSGLVGGAGCLLALGLDHFFQIREAPLHPRLSSAAEEKVPVIRPRRRSSCVSLGETAASYYGSCKIFRRPSLPCISREQMILWDWDLKQWYKPHYQNSGGGNGVDLSVLNEARNMVSDLLTDPSLPPQVISSLRSISSLMGAFSGSCRPKINPLTPFPGFYPCSEIEDPAEKGDRKLNKGLNRNSLPTPQLRRSSGTSGLLPVEQSSRWDRNNGKRPHQEFGISSQGCYLNGPFNSNLLTIPKQRSSSVSLTHHVGLRRAGVLSSLSPVNSSNHGPVSTGSLTNRSPIEFPDTADFLNKPSVILQRSLGNAPNTPDFYQQLRNSDSNLCNSCGHQMLKYVSTSESDGTDCCSGKSGEEENIFSKESFKLMETQQEEETEKKDSRKLFQEGDKWLTEEAQSEQQTNIEQEVSLDLILVEEYDSLIEKMSNWNFPIFELVEKMGEKSGRILSQVMYTLFQDTGLLEIFKIPTQQFMNYFRALENGYRDIPYHNRIHATDVLHAVWYLTTRPVPGLQQIHNGCGTGNETDSDGRINHGRIAYISSKSCSNPDESYGCLSSNIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYNDRSVLENHHAASAWNLYLSRPEYNFLLHLDHVEFKRFRFLVIEAILATDLKKHFDFLAEFNAKANDVNSNGIEWSNENDRLLVCQVCIKLADINGPAKVRDLHLKWTEGIVNEFYEQGDEEANLGLPISPFMDRSSPQLAKLQESFITHIVGPLCNSYDAAGLLPGQWLEAEEDNDTESGDDEDGEELDTEDEEMENNLNPKPPRRKSRRRIFCQLMHHLTENHKIWKEIVEEEEKCKADGNKLQVENSSLPQADEIQVIEEADEEE
What is the function of this protein?
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological process (PubMed:14592490, PubMed:21393242).  Regulates angiogenesis by inhibiting the cAMP-dependent guanine nucleotide exchange factor RAPGEF3 and downstream phosphatidylinositol 3-kinase gamma-mediated signaling (PubMed:21393242).  Controls cardiac contractility by reducing cAMP concentration in cardiocytes (By similarity).
What are the official names of this protein?
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B, CGIPDE1, CGIP1, Cyclic GMP-inhibited phosphodiesterase B, CGI-PDE B.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family. PDE3 subfamily.
Protein: RLMH_METSB
Sequence: MRLILLCVGRCKAGPETELSQRYIERANAAGRALGFPRVELREFDESRAREPALRKAAEAKTILASLSPGARLVALDESGALVSSREFSAFLGKTRDEGAPALTLAIGGADGLSGEILEAASPIVSFGRMTFPHQLVRIMAAEQLYRAMTILAGHPYHRD
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRD_PECAS
Sequence: MFYPVIKKALFQLDPERAHELTFQQLRRITNTPFEFLVRQSVPTKPVTCMGLSFKNPLGLAAGLDKDGECIDALGAMGFGFIEVGTVTPRPQSGNDKPRLFRVVEAEGLINRMGFNNKGVDYLVENVKKTRFGGVLGINIGKNKDTPVEQGKDDYLICMDKVYPHAGYIAINISSPNTPGLRSLQYGEALDDLLLAIKNKQTELKEKHQKYVPVAVKIAPDLSEEELIQIADSLVRYNIDGVIATNTTLDRKLIQGLNHCGQTGGLSGRPLQTSSTEIIRRLSQELAGRLPIIGVGGIDSLVAAREKMDAGASLVQIYSGFIFHGPRLIKDIVTHI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HEMH_HELAH
Sequence: MNLAQENLNSPNNLGNNATKSPKETVILLNMGGPNSLYEVGVFLKNMFDDPFILTIKNNFMRKMVGKMIVNSRIEKSKKIYEKLGGKSPLTPITFALTERLNELDPSRFYTYAMRYTPPYASMVLQDLALKEVESLVFFSMYPQYSSTTTLSSFNDAFNALKSLETFRPKVRVIERFYASEKLNEIILNTILSTLNNHKSQDFVLIFSVHGLPKSIIDAGDTYQQECEHHVDLLKDLMRQKNIHFKQVLLSYQSKLGPMKWLEPSTEGLIEKHRKSNIIIYPLAFTIDNSETLYELEIQYRLMAARLAIKEYLVCPCLNDSIEFAKFIIELVKNLKDE
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_HAEIN
Sequence: MTNTTMQPNRLRIALQKKGRLSQDCAILLKQCGVKINWNEQRLIAYAENLPIEILRVRDDDIPGLIFDGVVDLGIIGENVLEEEELGRRAANETVTYKKLRQLDFGDCRLSLAVDRDCHYENVKDLANRRIATSYPHLLKRYMNENGVSFKSCLLNGSVEVAPSAGIAYAICDLVSSGATLEANGLKEVDVIYRSKACLIQRAEPLESTKQALVDKLLTRIQGVQQAAESKYIMLHAPKEKLEKITALLPGVENPTILPLASDTTRVAMHVVSQENLFWETMEQLKEAGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAP_TAROF
Sequence: MAVAEFEITSSLSPSNIFKAFVIDFDTIAPKAEPETYKSIKTIEGDGGVGTIKSITYSDGVPFTSSKHKVDAIDSNNFSISYTIFEGDVLMGIIESGTHHLKFLPSADGGSVYKHSMVFKCKGDAKLTDENVSLMKEGLKKTFKAIETYVISHPEAC
What are the official names of this protein?
Root allergen protein, RAP.
What is the protein family that this protein belongs to?
Belongs to the BetVI family.