PharMolix/UniProtQA huggingface dataset:
Protein: PNP_CHRSD
Sequence: MNPVKKTFQYGHSTVTLETGRIARQATGAVMVTMDDTVVLCTVVAKKDVNPAQPFFPLSVHYQEKTYAVGKIPGGFFKREGRPTEKETLTSRLIDRPIRPLFPNGFMNEVQVVCTVLSTDRNHDPDIAAMLGTSAALAISGVPFNGPIGAARVGFNEDKGYFLNPTVEELESSELNMVVAGTEKAVLMVESEAKELLEDEMLGAVLFGHQEMQAAITAIQALADEAGKPRWDWQPPTDDTTLKSALAAEFEAKVGEAYRITDKMARQDALSALKDEALERLAGEESGQYAADDVKGAFASLEKRVVRSRIIQGEPRIDGRDHRTVRPLSIEVGTLPKTHGSAVFTRGETQAVVVATLGTLRDAQLIESLEGERKDRFLLHYNFPPYSVGEAGFMGGPKRREIGHGRLARRGVQAMLPSEEDFPYTIRVVSEITESNGSSSMASVCGSSLALMDAGVPLKAPVAGIAMGLVKDEDGFAVLTDILGDEDHLGDMDFKVAGSTAGVTALQMDIKIEGINEEIMETALQQAHEARLHILEQMNTVIAQSRSEVSDNAPSMATIKIDPDKIRDVIGKGGATIRKICDDTGASIDLDDDGTVRIYAEDKTAAKAAIDTVLAITAEPEIGKLYRGTVARITDFGAFVTFMPGTDGLVHISQIVPERVNDVRDYLSEGQEVIVKVLDIDNRNRVKLSIKEVTAEEKAAFEATPAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOA_BURA4
Sequence: MNLAAYYPVLLFLLVGTGLGIALVSIGKLLGPNKPDVEKNAPYECGFEAFEDARMKFDVRYYLVAILFIIFDLETAFLFPWGVALRDIGWPGFIAMMIFLLEFLLGFAYIWKKGGLDWE
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IDI2_BACC0
Sequence: MVRAKRKLDHIEYALSTGQSRTHGFHDIEFVHQSLPNSSYETITCETKIGELSLSSPIFINAMTGGGGEKTLHINEQLAYVAKHHNLAMAVGSQMAALKDESEAASYKIIRKVNPNGIFFANLGSEATVEQAERAVDMVGANALQIHLNVIQELTMPEGDRDFTGVLQRIEKIVLNSKVPVIVKEVGFGMSKETMQQLASVGVTAIDIGGQGGTNFAAVENERRQRMLSYFNNWGIQTATSIIEATSTNNNLSFIASGGIQTALDVAKAIALGANTTAFAGYFLRILMEDGIEKLVDEIDLLHTDLKFIMTALGAKTIEELQSVPLVIKGETYHWLTQRGIDTTHYSRR
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLTR_BACSU
Sequence: MNIQLLQVFLTTAREGSISKAALTLNYAQSNVTNKIQQLENDLQTKLFYRHSRGITLTPPGQILVSYSEKILHTIEEARAAMGESSAPSGPLRIGSMETTAAVWLPQLLAHYNNLYPNVDLNLVTGPTEQQIQAVLHYELNGAFISGPIEHPDLVQEKVLDEEMVLVTSASHPVISSIQDVQTQTMLVFRKGCSYRAKLNHILQEEGLLPIKLMEFGILEAIIGCVSAGLGISLLPRSIIASHEKEGRIRSHTISDKYSFVSTMFIRRKDTLITPALSAFLTHMRDHFQIKRPDQS
What is the function of this protein?
Positive regulator of glutamate biosynthesis (gltAB genes).  Negatively regulates its own expression.
What are the official names of this protein?
HTH-type transcriptional regulator GltR.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: HBSAG_HBVE4
Sequence: MGLSWTVPLEWGKNHSTTNPLGFFPDHQLDPAFRANTRNPDWDHNPNKDHWTEANKVGVGAFGPGFTPPHGGLLGWSPQAQGMLKTLPADPPPASTNRQSGRQPTPITPPLRDTHPQAMQWNSTTFHQALQDPRVRGLYFPAGGSSSGTVNPVPTTVSLISSIFSRTGDPAPNMEGITSGFLGPLLVLQAGFFLLTKILTIPQSLDSWWTSLNFLGGAPVCLGQNSQSPTSNHSPTSCPPICPGYRWMCLRRFIIFLFILLLCLIFLLVLLGYQGMLPVCPLIPGSSTTITGPCRTCTTLAQGTSMFPSCCCSKPSDGNCTCIPIPSSWAFGKFLWEWASARFSWLSLLVPFVQWFAGLSPTVWLSVIWMMWYWGPSLYNILSPFIPLLPIFFCLWVYI
What is the function of this protein?
The middle envelope protein plays an important role in the budding of the virion.  It is involved in the induction of budding in a nucleocapsid independent way.  In this process the majority of envelope proteins bud to form subviral lipoprotein particles of 22 nm of diameter that do not contain a nucleocapsid.
What are the official names of this protein?
Large envelope protein, L glycoprotein, L-HBsAg, LHB, Large S protein, Large surface protein, Major surface antigen.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus major surface antigen family.
What are the subcellular locations of this protein?
Virion membrane.
Protein: RS10_STAAB
Sequence: MAKQKIRIRLKAYDHRVIDQSAEKIVETAKRSGADVSGPIPLPTEKSVYTIIRAVHKYKDSREQFEQRTHKRLIDIVNPTPKTVDALMGLNLPSGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: PYRH_CAMJR
Sequence: MQERKRVLVKFSGEALAGENGFGIENSILKFIASEIKELIKNQIEVGIVIGGGNIIRGVSAAKGGLIKRTSGDHMGMLATVINAIAIQEALESSGLEVRVQSAIQMEAFCETYIMRRAQRHLEKGRVVVFAAGTGNPYFTTDTTAILRAVEIDADMVIKATKVNGVYDKDPKQFDDAVFLNTLSYDEAMQDNIKVMDDTAIALAKDNKLPIVVCNMFEEGNLLKIIQGDTSLCSIVKNN
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YLAT1_HUMAN
Sequence: MVDSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN
What is the function of this protein?
Heterodimer with SLC3A2, that functions as an antiporter which operates as an efflux routeby exporting cationic amino acids from inside the cells in exchange with neutral amino acids plus sodium ions and may participate in nitric oxide synthesis via the transport of L-arginine (PubMed:9878049, PubMed:9829974, PubMed:17329401, PubMed:10080182, PubMed:10655553, PubMed:15756301, PubMed:15776427, PubMed:14603368).  Also mediates arginine transport in non-polarized cells, such as monocytes, and is essential for the correct function of these cells (PubMed:15280038, PubMed:31705628).  The transport mechanism is electroneutral and operates with a stoichiometry of 1:1 (By similarity).  In vitro, Na(+) and Li(+), but also H(+), are cotransported with the neutral amino acids (By similarity).
What are the official names of this protein?
Y+L amino acid transporter 1, Monocyte amino acid permease 2, MOP-2, Solute carrier family 7 member 7, y(+)L-type amino acid transporter 1, Y+LAT1, y+LAT-1.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein.
Protein: FABA_HYPNA
Sequence: MQGPHDFHTPKSSYSKEDLLESGKGGYFGPGNAQLPAPPMLMMDRITEISLDGGAFGKGHVVGELDITPDLWFFQCHFPGDPVMPGCLGLDAMWQIVGYWLGWSGSPGKGRALGVGEVKFTGEITPDKKLVRYEIDIKRVRRGKLNLGIADGRVYVDGEHVYTAIDMKVGLKNVLGGAGDLPAS
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_VIBCM
Sequence: MPVVKVRENEPFDVALRRFKRSCEKAGILSEVRRREHYEKPTTVRKRAKAAAQKRHAKKLARENARRVRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: Y173_METJA
Sequence: MVEDSFLTDTQIKVLKLRKKGLTQEEIAKMLGTSRANISMIEKRAKENIKKAYNTIKIYNRIMAPLSIEIEEGTDVLEIPDIVFKKADEEGIKVKYNTLELIELIKENASEFIEKRTVKKKFKIYILENGDLDVGGS
What is the function of this protein?
Putative transcriptional regulator.
What are the official names of this protein?
Putative transcriptional regulatory protein MJ0173.
What is the protein family that this protein belongs to?
Belongs to the Tfx family.
Protein: P102A_LUPLU
Sequence: MGVFTFEDESTSTIAPARLYKALVKDADAIIPKAVEAIQSIETVEGNGGPGTIKKLTLIEGGETKYVLHKIEAVDEANLRYNYSIVGGVGLPDTIEKISFETKLVEGANGGSIGKVTIKIETKGDAQPNEEEGKAAKARGDAFFKAIENYLSAHPEYN
What is the function of this protein?
Class II ribonuclease (RNase) (By similarity).  Binds to cytokinins (By similarity).  Interacts with melatonin (By similarity).
What are the official names of this protein?
Class 10 plant pathogenesis-related protein 2A, LlPR10.2a, Ypr-10.2a.
What is the protein family that this protein belongs to?
Belongs to the BetVI family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: MTND_STRM5
Sequence: MSRLRIYDDTRPESPLLDTQDGAIIAAELQKIGVTFERWQATAPVAPGASQEEVFAAYRADIDRLVAERGFKSVDVASIAPDNPNRAELRRKFLDEHFHKEDEVRFFVAGSGLFTLHVGDKVYEIECVKDDLIAVPDGTTHWFDMGDEPSFVAIRFFTEPDGWVGHFTGTDIAQKFPRYVPTQAS
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: TRMD_POLNS
Sequence: MRFDVVTLFPEMFSALTQWGITGRACEQFLASVHLWNPRDFCSDPRKTVDDRAYGGGPGMVMMVKPLEDTVAGIRASHEAAGIKSGPICLLAPQGERFSQKIATDILSYGNLSFICGRYEAVDQRFVDRNVDLQLSIGDFVLSGGEIPAMAMMDAVIRLIPGALGDGQSATQDSFMNGLLDYPHYTRPEIYENLSVPDVLLGGHHAKIVDWRRQKSLELTFRLRLDLIESARAKGLLTREDEQFLRSL
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA1_PARD8
Sequence: MKSYELITILGPTASGKTTFAAALAAQLDTEIISADSRQIYRSMDIGTGKDLADYNVNGKQIPYHLIDICEPGYKYNVFEYQHDFFRVYEDMKRRGKLPILCGGTGMYIEAVLKGYKLLDVPQNPELRESLRNKTLEELETILASYKILHNKTDVDTAQRAIRAIEIEEYYKTQAPDVNEYNPINSLIIGIHIDRELRREKISRRLRTRLDEGMVDEVRTILATGVKPEDLIYYGLEYKFLTLYIIGELSFEEMVSQLEIAIHQFAKRQMTWFRGMERRGCEIHWIDATLPTEEKIATTMRILNNQL
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase 1, Dimethylallyl diphosphate:tRNA dimethylallyltransferase 1, DMAPP:tRNA dimethylallyltransferase 1, DMATase 1, Isopentenyl-diphosphate:tRNA isopentenyltransferase 1, IPP transferase 1, IPPT 1, IPTase 1.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: Y443_CHLPN
Sequence: MSQPPINPLGQPQVPAAASPSGQPSVVKRLKTSSTGLFKRFITVPDKYPKMRYVYDTGIIALAAIAILSILLTASGNSLMLYALAPALALGALGVTLLISDILDSPKAKKIGEAITAIVVPIIVLAIAAGLIAGAFVASSGTMLVFANPMFVMGLITVGLYFMSLNKLTLDYFRREHLLRMEKKTQETAEPILVTPSADDAKKIAVEKKKDLSASARMEEHEASQRQDARHRRIGREAQGSFFYSSRNPEHRRSFGSLSRFKTKPSDAASTRPASISPPFKDDFQPYHFKDLRSSSFGSGASSAFTPIMPASSRSPNFSTGTVLHPEPVYPKGGKEPSIPRVSSSSRRSPRDRQDKQQQQQNQDEEQKQQSKKKSGKSNQSLKTPPPDGKSTANLSPSNPFSDGYDEREKRKHRKNK
What are the official names of this protein?
Uncharacterized protein CPn_0443/CP_0310/CPj0443/CpB0459.
What is the protein family that this protein belongs to?
Belongs to the chlamydial CPn_0443/CT_005/TC_0273 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IBB1_WHEAT
Sequence: AAKKRPWKCCDQAVCTRSIPPICRCMDQVFECPSTCKACGPSVGDPSRRVCQDQYV
What are the official names of this protein?
Bowman-Birk type proteinase inhibitor I-2B.
What is the protein family that this protein belongs to?
Belongs to the Bowman-Birk serine protease inhibitor family.
Protein: FRE1_NYCIN
Sequence: GLLDALSGILGL
What is the function of this protein?
Antimicrobial peptide with selective activity.  Is only active against Micrococcus luteus (MIC=25 ug/ml) and not against Bacillus cereus, Escherichia coli, Leuconostoc mesenteroides, Micrococcus luteus, Pastewella haemolytica, Staphylococcus aureus, Streptococcus faecalis and Streptococcus uberis.
What are the official names of this protein?
Frenatin-1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Frenatin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AP21_ORYSI
Sequence: MELDLNNVAEGVVEKHETAARSDSGTSESSVLNGEASGAATTPAEEGSSSTPPPPPPPPAAVLEFSILRSSASASGENDADDDEEEEATPSPPPHHQHQQLLVTRELFPSAAPSPQHWAELGFLRPDPPRPHPDIRILAHAPPPAPPPPPPQPQPQAAKKSRRGPRSRSSQYRGVTFYRRTGRWESHIWDCGKQVYLGGFDTAHAAARAYDRAAIKFRGVEADINFNLSDYEEDMRQMKSLSKEEFVHVLRRQSTGFSRGSSKYRGVTLHKCGRWEARMGQFLGKKYIYLGLFDSEVEAARAYDKAAIKCNGREAVTNFEPSTYDGELPTDAAAQGADVDLNLSISQPAASQQSPKRDSGSLGLQIHHGSFEGSEFKRAKNDAAPSELASRPHRFPLLTEHPPIWTAQPHPLFPNNEDASRSSDQKRKPSEGVAVPSWAWKQVSHHHPAPPHTLPLPFFSSSSSSPSSSSAAASSGFSKAATTAAAAQHTATLRFDPTAPSSSSSSRHHHHH
What is the function of this protein?
Probable transcription factor (By similarity).  Involved in spikelet transition.  Regulator of starch biosynthesis especially during seed development (e. g.  endosperm starch granules); represses the expression of type I starch synthesis genes.  Prevents lemma and palea elongation as well as grain growth (By similarity).
What are the official names of this protein?
APETALA2-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. AP2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1570_SERP5
Sequence: MAKLFTLCWKYLRAIVLIYLCLFAGNAIAALLPIAIPGSIIGMLLLFALLSTQIMPARWVKPGCHLLIRYMVLLFVPIGVGVMKYYDQILDHLGPLVVSCIISTLMVLVVVGYTSHYFHRERRIVGKPDAAEGEK
What are the official names of this protein?
UPF0299 membrane protein Spro_1570.
What is the protein family that this protein belongs to?
Belongs to the UPF0299 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RLMKL_LEGPL
Sequence: MNYSLFISCAKGLEYLLEDELKGLGLHVTQVSPQGVYGEASLPVIYNLCLWSRLANRIQLILFSGHAAKEQAVHQLCTDFHWQTVFTHDKTIAIEFHGASEQIRNTMFGAQIVKDGIVDHFRRLNGSRPSVDKEKPQILIHAHLKNDILTVSFDLVGYSLHQRGYRKKAGKAPLKENVAAAMLLRAKWPELAAQGYGLHDPFCGSGTLVIEAAMMAAHIAPGLLRQDQSLQYWARHQSSLWEKLRTQALQQVKPLAVKLVGTDTDSKVVALARSNAERAGVLPLVEFNTLSLNACRPGTKRGLVVCNPPYGERLGEVTQLVPLYQQLGTTLHTCYQGWQAAILTSSPVLAKALGLRADKQYTLYNGPLECKLYCLTLSAANKLKNTPNAPLSDNAQMLFNRLEKNRNHLQKWARKNQITCYRIYDADLPEYAYAIDIYNDYAVLQEYAPPASIPVHKAEKRSLEMLQVVPRALGIHPEKLIVKQRKQQKGSEQYQKIGKTSQRQIVTEGKAKLIVNLYDYLDTGLFLDHRLMRLKFAQLEQGTRFLNCFCYTASASVHAALAGALTTNVDLSKTYLLWAEDNFRLNDINLSKHQFLQYDCKEWMKTTRDKFDVIFLDPPSFSNSKRMSDILDIQRDHVSLINMAMRLLNPDGVLYFSTNLRQFKLEPMLKEKYAVQDITPQTIDQDFKRNSKIHHCFKIVMPHFADN
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESRP1_RAT
Sequence: MTASPDYLVVLFGITAGATGAKLGSDEKELILLLWKVVDLANKKVGQLHEVLVRPDQLELTEDCKEETKIDAENLSSAPQLDQALRQFNQSVSNELNIGVGTSFCLCTDGQLHVRQILHPEASKKNVLLPECFYSFFDLRKEFKKCCPGSPDLDKLDVAAMAESLNFEKNDSMSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKTELIDGNTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNEVAQFLSKENQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTAPIIPVLPQQFVPPTNVRDCVRLRGLPYAATIEDILDFLGEFSTDIRTHGVHMVLNHQGRPSGDAFIQMKSTDRAFMAAQKYHKKTMKDRYVEVFQCSAEEMNFVLMGGTLNRNGLSPPPCLSPPSYTFPAPAAVIPTEAAIYQPSLLLNPRALQPSTAYYPAGTQLFMNYTAYYPSPPGSPNSLGYFPTAANLSSVPPQPGTVVRMQGLAYNTGVKEILNFFQGYQYATEDGLVHANDQARTVPKEWVCI
What is the function of this protein?
mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms.  Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2.  Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT).  Acts by directly binding specific sequences in mRNAs.  Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2 (By similarity).  Regulates splicing and expression of genes involved in inner ear development, auditory hair cell differentiation, and cell fate specification in the cochlear epithelium (By similarity).
What are the official names of this protein?
Epithelial splicing regulatory protein 1, RNA-binding motif protein 35A, RNA-binding protein 35A.
What is the protein family that this protein belongs to?
Belongs to the ESRP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRMD_XANCP
Sequence: MRIDVISLFPEFIAQCAAFGVVGRAQERGLLELKGWNPRDHAQGNYRRVDDRPFGGGPGMVMLIEPLRACLEVAQAADARPAPVIYLSPQGRPLTQPLARELAQLPRMVLLCGRYEGVDERFLDQAVDMEISIGDYVLSGGELGAAVLVDVVTRLQDGVLNDAESAAQDSFEGPQGLLDCPHYSHPSSHAWGDVPEVLRSGNHGAIARWRRQQSLGRTWLRRPELLDEATLDKQDRRLLEEFRRELAPGDEK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SP24D_ANOGA
Sequence: MTLADRVPLALAALAYLALVSGVRFHLSEQNDVLPGGSQARRPFFQGARIVGGSVASEGQFPHQVALLRGNALTCGGSLIESRWVLTAAHCVYNGALVVPASSIVVVAGSVSLSNGVRRAVARVIPHERYGNFKNDVALLQLQLSLPSSAYIRPIALRTTSVPAGSEVVISGWGRMYQGGPVSNMLRYNRATVVADQQCRMATGISTGLICFTSPVNNGACNGDSGGPAILNNQLVGVANFIINYCGSASPDGYARVSDFVTWIQTTMRRY
What are the official names of this protein?
Serine protease SP24D, AgSp24D.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: ENGB_HYDCU
Sequence: MQHPLYQQATYLKSAPDLSHCPEDFGYEVAFAGRSNAGKSSALNVITSQRGLAKTSKTPGRTQLINFFECDEQRKLVDLPGYGYAKVNVNTKRAWERSLSQYIEVRSSLKGLIMMVDSRMPPTEIDLMMLDWTLTLNLPVHILLTKSDKLKKGPAQNSLLKMRQLLNEKYPHATVQLFSSLKRQGLDEVWAKLDEWMEYERPVKSQPETKES
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: COQ4_DROPE
Sequence: MMQRCWRLTVPLAKRGLAVVTHTRQAVVSDNPEAENLDGFEQQYLKERIEITTFQRMLLGAGSSIAAILDPRRHDMIACLGETTGEDALWNIMDTMHESEEGQRIMVEKPRIHTSTIDFKRLESLPADTFGAAYVKFLKDNKVTPDSRMAVRFLEDPKLAYLMTRYRECHDLIHTVLDMPTNMLGEVAVKWVEALNTGLPMCYGGAVFGAVRLRPKQRRAYLKHYLPWALENGKQMKPLMPVYWEERWEQNVNELRAELGIKLLNKV
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial, Coenzyme Q biosynthesis protein 4 homolog.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: 4CL1_NARPS
Sequence: MGSIPSEKETIFRSKLPDIYVPDHLPLHSYCFQNLHQFSDRPCLIDGFTNKTLTYAEVELASKRVGAGLHRLGLRQGHVVMLLLPNSIEFVLSFIGASLLGAMSTTANPFYTSAEIHKQAAAAGAKIIVTESCHVSKLQGLEGISRIVVIDDAVRVPENVMHFSELESTDEAELPRIDVHPDDVVALPYSSGTTGLPKGVMLTHNGLVTSVAQQVDGENPNLHFSEDDVLLCVLPLFHIYSLNSVLLCGLRAGAAIVLMRKFEIVRLMELVEKYRVTIAPFVPPIVVEMVKNEAVDRYDLSSIRVVMSGAAPMGKELENKLREKLPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEVKSGSCGTVVRNAELKIIDPETGFSLSRNQPGEICIRGNQIMKGYLNNPEATKQTIDEEGWLHTGDIGFVDDDDEIFIVDRLKELIKYKGFQVAPAELEAMLITHPNMADAAVVSIKDDSCGELPVAFIVRSNGSEITEDEIKKYISKQVVFYKRIHRVFFIEAIPKAPSGKILRKELRARLAAECPNGRQL
What is the function of this protein?
Produces CoA thioesters of a variety of hydroxy- and methoxy-substituted cinnamic acids, which are used to synthesize several phenylpropanoid-derived compounds, including anthocyanins, flavonoids, isoflavonoids, coumarins, lignin, suberin and wall-bound phenolics.
What are the official names of this protein?
4-coumarate-CoA ligase 1.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: NOVS_STRNV
Sequence: MTDRWLVTGAAGMLGRDLVALLRGLNEPVVAITRHDLDITDRLSVRAVVDRHRPTTIVNCAAWTRFGEAEAGESAALLVNGGGARELAAVCRDRSIRLVHLSTDYVFDGTSRRPYAESAVTSPINAYGRTKQAGEQAVLDLLPDDGTIVRTAWLYGRHGMNFIRKMVRLEQLRETVDVVDDQWGQPTWTVDLAQQIVALVRHGASGVFHGTSAGEATWYDLARMTFRLLGADPGRVRPVPSDRIAGGELRPRYTVLGHDAWREAGLTPIRHWTTALTQAFPLLNADES
What is the function of this protein?
Reduces the product formed from the reaction of NovW with dTDP-4-keto-6-deoxy-D-glucose to result in dTDP-5-methyl-L-rhamnose in the novobiocin biosynthesis pathway, an aminocoumarin family antibiotic that targets bacterial DNA gyrases.
What are the official names of this protein?
dTDP-4-keto-6-deoxy-D-glucose reductase, Novobiocin biosynthesis protein S.
What is the protein family that this protein belongs to?
Belongs to the dTDP-4-dehydrorhamnose reductase family.