PharMolix/UniProtQA huggingface dataset:
Protein: EUTA_SALTY
Sequence: MNTRQLLSVGIDIGTTTTQVIFSRLELVNRAAVSQVPRYEFIKRDISWQSPVFFTPVDKQGGLKEVELKALILAQYQAAGIAPESVDSGAIIITGESAKTRNARPAVMALSQSLGDFVVASAGPHLESVIAGHGAGAQSLSEQRMCRVLNIDIGGGTSNYALFDAGKVSGTACLNVGGRLLETDAQGRVVYAHQPGQMIIDEVFGSGTDARALAAAQLGQVARRMADLIVEVITGALSPLAQSLMQTGLLPADITPEVITLSGGVGECYRNQPADPFCFSDIGPLLATALHEHPRLREMNVQFPAQTVRATVIGAGAHTLSLSGSTIWLEDVQLPLRNLPVAIPQDDADLVNAWRQALLQLDLDPQTDAYVLALPATLPVRYAALLTVINALTAFVARYPNPHPLLVVAEQDFGKALGMLLRPQLPQLPLAVIDEVVVRAGDYIDIGTPLFGGSVVPVTVKSLAFPS
What is the function of this protein?
Expression of the eut operon allows this bacteria to use ethanolamine as a carbon, nitrogen and energy source.  It relies on cobalamin (vitamin B12) both as a cofactor for the ethanolamine ammonia-lyase (EAL) activity and to induce the operon (PubMed:3045078).  EA enhances bacterial survival in macrophages in a concentration-dependent manner, suggesting it is an important nutrient during infection (PubMed:29531136).
What are the official names of this protein?
Ethanolamine ammonia-lyase reactivase EutA.
What is the protein family that this protein belongs to?
Belongs to the EutA family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: DRUE_ECOU4
Sequence: MINKNKVTERSGIHDTVKSLSENLRKYIEAQYHIRDEGLIAERRALLQQNETIAQAPYIEATPIYEPGAPYSELPIPEAASNVLTQLSELGIGLYQRPYKHQSQALESFLGEDASDLVIATGTGSGKTESFLMPIIGKLAIESSERPKSASLPGCRAILLYPMNALVNDQLARIRRLFGDSEASKILRSGRCAPVRFGAYTGRTPYPGRRSSRRDELFIKPLFDEFYNKLANNAPVRAELNRIGRWPSKDLDAFYGQSASQAKTYVSGKKTGKQFVLNNWGERLITQPEDRELMTRHEMQNRCPELLITNYSMLEYMLMRPIERNIFEQTKEWLKADEMNELILVLDEAHMYRGAGGAEVALLIRRLCARLDIPRERMRCILTSASLGSIEDGERFAQDLTGLSPTSSRKFRIIEGTRESRPESQIVTSKEANALAEFDLNSFQCVAEDLESAYAAIESLAERMGWQKPMIKDHSTLRNWLFDNLTGFGPIETLIEIVSGKAVKLNILSENLFPDSPQQIAERATDALLALGCYAQRASDGRVLIPTRMHLFYRGLPGLYACIDPDCNQRLGNHSGPTILGRLYTKPLDQCKCASKGRVYELFTHRDCGAAFIRGYVSSEMDFVWHQPNGPLSEDEDIDLVPIDILVEETPHVHSDYQDRWLHIATGRLSKQCQDEDSGYRKVFIPDRVKSGSEITFDECPVCMRKTRSAQNEPSKIMDHVTKGEAPFTTLVRTQISHQPASRPIDGKHPNGGKKVLIFSDGRQKAARLARDIPRDIELDLFRQSIALACSKLKDINREPKPTSVLYLAFLSVLSEHDLLIFDGEDSRKVVMARDEFYRDYNSDLAQAFDDNFSPQESPSRYKIALLKLLCSNYYSLSGTTVGFVEPSQLKSKKMWEDVQSKKLNIESKDVHALAVAWIDTLLTEFAFDESIDSTLRIKAAGFYKPTWGSQGRFGKALRKTLIQHPAMGELYVEVLEEIFRTHLTLGKDGVYFLAPNALRLKIDLLHVWKQCNDCTALMPFALEHSTCLACGSNSVKTVEPSESSYINARKGFWRSPVEEVLVSNSRLLNLSVEEHTAQLSHRDRASVHATTELYELRFQDVLINDNDKPIDVLSCTTTMEVGVDIGSLVAVALRNVPPQRENYQQRAGRAGRRGASVSTVVTYSQNGPHDSYYFLNPERIVAGSPRTPEVKVNNPKIARRHVHSFLVQTFFHELMEQGIYNPTEKTAILEKALGTTRDFFHGAKDTGLNLDSFNNWVKNRILSTNGDLRTSVAAWLPPVLETGGLSASDWFAKVAEEFLNTLHGLAEIVPQIAALVDEENEDDEQTSGGMKFAQEELLEFLFYHGLLPSYAFPTSLCSFLVEKIVKNIRGSFEVRTVQQPQQSISQALSEYAPGRLIVIDRKTYRSGGVFSNALKGELNRARKLFNNPKKFIHCDKCSFVRDPHNNQNSENTCPICGGILKVEIMIQPEVFGPENAKELNEDDREQEITYVTAAQYPQPVDPEDFKFNNGGAHIVFTHAIDQKLVTVNRGKNEGGSSGFSVCCECGAASVYDSYSPAKGAHERPYKYIATKETPRLCSGEYKRVFLGHDFRTDLLLLRITVGSPLVTDTSNAIVLRMYEDALYTIAEALRLAASRHKQLDLDPAEFGSGFRILPTIEEDTQALDLFLYDTLSGGAGYAEVAAANLDDILTATLALLEGCECDTSCTDCLNHFHNQHIQSRLDRKLGASLLRYALYGMVPRCASPDIQVEKLSQLRASLELDGFQCLIKGTQEAPMIVSLNDRSVAVGSYPGLIDRPDFQHDVYKSKNTNAHIAFNEYLLRSNLPQAHQNIRKLLR
What is the function of this protein?
Component of antiviral defense system Druantia type I, composed of DruA, DruB, DruC, DruD and DruE.  Expression of Druantia in E. coli (strain MG1655) confers resistance to phage lambda, SECphi18, SECphi27 and T4 (PubMed:29371424).  This protein is probably a helicase (Probable).
What are the official names of this protein?
Druantia protein DruE, Probable ATP-dependent helicase DruE.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLFB_STAAN
Sequence: MKKRIDYLSNKQNKYSIRRFTVGTTSVIVGATILFGIGNHQAQASEQSNDTTQSSKNNASADSEKNNMIETPQLNTTANDTSDISANTNSANVDSTTKPMSTQTSNTTTTEPASTNETPQPTAIKNQATAAKMQDQTVPQEANSQVDNKTTNDANSIATNSELKNSQTLDLPQSSPQTISNAQGTSKPSVRTRAVRSLAVAEPVVNAADAKGTNVNDKVTASNFKLEKTTFDPNQSGNTFMAANFTVTDKVKSGDYFTAKLPDSLTGNGDVDYSNSNNTMPIADIKSTNGDVVAKATYDILTKTYTFVFTDYVNNKENINGQFSLPLFTDRAKAPKSGTYDANINIADEMFNNKITYNYSSPIAGIDKPNGANISSQIIGVDTASGQNTYKQTVFVNPKQRVLGNTWVYIKGYQDKIEESSGKVSATDTKLRIFEVNDTSKLSDSYYADPNDSNLKEVTDQFKNRIYYEHPNVASIKFGDITKTYVVLVEGHYDNTGKNLKTQVIQENVDPVTNRDYSIFGWNNENVVRYGGGSADGDSAVNPKDPTPGPPVDPEPSPDPEPEPTPDPEPSPDPEPEPSPDPDPDSDSDSDSGSDSDSGSDSDSESDSDSDSDSDSDSDSDSESDSDSESDSDSDSDSDSDSDSDSESDSDSDSDSDSDSDSDSESDSDSESDSESDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSRVTPPNNEQKAPSNPKGEVNHSNKVSKQHKTDALPETGDKSENTNATLFGAMMALLGSLLLFRKRKQDHKEKA
What is the function of this protein?
Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps.
What are the official names of this protein?
Clumping factor B, Fibrinogen receptor B, Fibrinogen-binding protein B.
What is the protein family that this protein belongs to?
Belongs to the serine-aspartate repeat-containing protein (SDr) family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Anchored to the cell wall by sortase A (By similarity).
Protein: APLF_HUMAN
Sequence: MSGGFELQPRDGGPRVALAPGETVIGRGPLLGITDKRVSRRHAILEVAGGQLRIKPIHTNPCFYQSSEKSQLLPLKPNLWCYLNPGDSFSLLVDKYIFRILSIPSEVEMQCTLRNSQVLDEDNILNETPKSPVINLPHETTGASQLEGSTEIAKTQMTPTNSVSFLGENRDCNKQQPILAERKRILPTWMLAEHLSDQNLSVPAISGGNVIQGSGKEEICKDKSQLNTTQQGRRQLISSGSSENTSAEQDTGEECKNTDQEESTISSKEMPQSFSAITLSNTEMNNIKTNAQRNKLPIEELGKVSKHKIATKRTPHKEDEAMSCSENCSSAQGDSLQDESQGSHSESSSNPSNPETLHAKATDSVLQGSEGNKVKRTSCMYGANCYRKNPVHFQHFSHPGDSDYGGVQIVGQDETDDRPECPYGPSCYRKNPQHKIEYRHNTLPVRNVLDEDNDNVGQPNEYDLNDSFLDDEEEDYEPTDEDSDWEPGKEDEEKEDVEELLKEAKRFMKRK
What is the function of this protein?
Histone chaperone involved in single-strand and double-strand DNA break repair (PubMed:17353262, PubMed:17396150, PubMed:21211721, PubMed:21211722, PubMed:30104678, PubMed:29905837).  Recruited to sites of DNA damage through interaction with branched poly-ADP-ribose chains, a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions (PubMed:17353262, PubMed:17396150, PubMed:21211721, PubMed:30104678).  Following recruitment to DNA damage sites, acts as a histone chaperone that mediates histone eviction during DNA repair and promotes recruitment of histone variant MACROH2A1 (PubMed:21211722, PubMed:30104678, PubMed:29905837).  Also has a nuclease activity: displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro (PubMed:17353262, PubMed:17396150).  Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage (PubMed:17353262, PubMed:17396150).  Together with PARP3, promotes the retention of the LIG4-XRCC4 complex on chromatin and accelerate DNA ligation during non-homologous end-joining (NHEJ) (PubMed:21211721, PubMed:23689425).  Also acts as a negative regulator of cell pluripotency by promoting histone exchange (By similarity).  Required for the embryo implantation during the epithelial to mesenchymal transition in females (By similarity).
What are the official names of this protein?
Aprataxin and PNK-like factor, Apurinic-apyrimidinic endonuclease APLF, PNK and APTX-like FHA domain-containing protein, XRCC1-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the APLF family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Cytoplasm, cytosol. Note=Localizes to DNA damage sites (PubMed:18474613, PubMed:18172500, PubMed:21211721, PubMed:23689425). Accumulates at single-strand breaks and double-strand breaks via the PBZ-type zinc fingers (PubMed:18172500).
Protein: F16A1_CUPTR
Sequence: MTRISLTRYLVEEQRKHNTIQPELRLLIEVVARACKAISNAVSKGALAGVLGSAGTGNVQGETQQKLDVIANEVLLDANEWGGHLAAMASEEMESFYEIPNRYPKGEYLLMFDPLDGSSNIDVNVSIGTIFSVLHMPKPGQTVTEADFLQPGTHQVAAGYAVYGPQTTLVLTVGNGVHMFTLDREAGSFVLTQSNVTIPEDTKEFAINMSNMRHWAPPVRKYIDECLAGDEGPRGKNFNMRWVASMVADVHRILTRGGIFMYPWDKREPEKPGKLRLMYEANPMAMLVEQAGGAATNGEQRILDVQPEKLHQRVSVILGSKNEVERVTRYHQEAQAKA
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1 1, FBPase class 1 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PD_GLUOX
Sequence: MEHFQQVEPFDYVIFGATGDLTMRKLLPALYNRLRMGQIPDDACIIGAARTELDREAYVARARDALERFLPSDILGPGLVERFLARLDYVTLDSSREGPQWDALKSLLAKAQPDRVRVYYFATAPQLYGSICENLNRYELITPTSRVVLEKPIGTNMATATAINDGVGQYFPEKQIYRIDHYLGKETVQNVLALRFANPLMNAAWSGEHIESVQITAVETVGVEGRAAYYDTSGALRDMIQNHLLQVLCLVAMEAPDSLEADAVRNAKLAVLNALRPITDATAATETVRAQYTAGVVDGENVPGYLEELGKPSATETYAAIRAWVDTPRWKNVPFYIRTAKRSGKKVSEIVVTFRPAATTMFGATPASNRLVLRIQPNEGVDLRLNVKNPALDVFNLRTADLDTSIRMEGGLPFPDSYERLLLDAVRGDPVLFIRRDEVEAAWRWVEPILEAWKHDKAPMQTYSAGSYGPEQATQLLASHGDTWHEASE
What is the function of this protein?
Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
What are the official names of this protein?
Glucose-6-phosphate 1-dehydrogenase, G6PD, G6PDH.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphate dehydrogenase family.
Protein: GLMS_CAUVC
Sequence: MCGIIGIVGKEPVADRLIESLKRLEYRGYDSAGVAGVVGGKVERRRAQGKIKALEAVLADEPLTATTGIGHTRWATHGAPNVRNAHPHTAGRVTLVHNGIIENFAELKAELAGMGRTFESDTDTEVIAQLIDVALAKGLAPLDAFKATLDRLTGAYALAVLIQGEADLLLGARRGSPLVVGEGQGEMFLGSDALAVGPFTNRVIYLEEGDYVALDHDSRRIFDASGARVERPVRVVPTSSVMLEKGNYRHFMEKEIHDQPEGCQRTIAAYVDTLTSKAAVPGDIDFATLDRIQIVACGTSYIAGVIGKYLIEQLADLPVDVEIASEFRYRTPALRPGSLVVAMSQSGETADTLAALRYCKAKGMKSAVVVNAQESTMAREVDVVWPIHCGPEIGVASTKAFTAQVSVMIALAIAAAKARGTIDAAEEQRLVKVLLEAPRLIAEAIGLEDAIKEIAADVAKARDVLYLGRGPMSALALEGALKLKEISYIHAEGYAAGELKHGPIALVDDQTPIVILAPYDSYFEKSASNMSEVMARGGQVIFITDTEGVKHAPAGAKVVVTAPASDPLVSTLVMSAPIQLLAYHVAVVKGADVDQPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHSE_METPB
Sequence: MAVYTDVSDEALRAFLQEYELGELLSYKGIAEGVENSNFYLHTSTGHYILTLYEKRVSEADLPFFINLMGHLARAGLACPQPVRNRAGTALGRLCGRPAAIVTFLEGVSLSRPNAEHCRALGAALAGLHAAGRDFPMVRENNLSVGAWRPLFAQAEAQADTVAPGLAARTRADLDILEGAWPKDLPGGVIHADLFTDNVFFIGDAVSGLIDFYFACTDAFAYDLAISLNAWCFDADGTFHRDKAGAMLAGYDAVRTLEPAEIAAIPVLARGAAMRFMLTRLVDWLNVPPGALVQPKDPLEYDRRLAFHRTAADARDYGWEG
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: CFA77_CHLRE
Sequence: MVWQPTSGQSAIDQDIRVGTQRGSMNQNPLLAHAPLGTVKPVLFNNPPPEKVFGYTPAKDPEGAREVMMVWKGHNASPGKDEVKPSPDFKTLNKMAVASGLSTAKDLPAFRKEHADVKLKTAHEVNAASPTRRSNLPTIPPSKQGNMFGMPSGYRTAEVVRSFGPEEPPVKYLVQGAYQDEWVRKNLEAEAAGSGRGRPYIPPAPTKAVLGHSYGASRYLQPPNNEEPWKMSKFKTVGPKVTQYSGGSVRASRTAPADGDEYAAAEAPAE
What are the official names of this protein?
Cilia- and flagella-associated protein 77, Flagellar-associated protein 77.
What is the protein family that this protein belongs to?
Belongs to the CFAP77 family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum.
Protein: LSRB_YERPE
Sequence: MRTQRLKKLALVCALGFACITTAQAAERIAFIPKLVGVGFFTSGGKGAVDAGKALGVDVTYDGPTEPSVSGQVQLINNFVNQGYNAIVVSAVSPDGLCPALKRAMQRGVKILTWDSDTKPECRSVYINQGTPNQLGSMLVDMAANQVKKEQAKVAFFYSSPTVTDQNQWVNEAKKKIQQEHPGWEIVTTQFGYNDATKSLQTAEGILKAYADLDAIIAPDANALPAAAQAAENLKRANVAIVGFSTPNVMRPYVERGTVKEFGLWDVVNQGKISVYVANEMLKKGDLNVGDKIDIPNIGVVEVSPNRVQGYDYEAKGNGIVLLPQRVIFTKENISKYDF
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Binds AI-2 and delivers it to the LsrC and LsrD permeases (By similarity).
What are the official names of this protein?
Autoinducer 2-binding protein LsrB, AI-2-binding protein LsrB.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 2 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TNG6_MOUSE
Sequence: MAASGPAAAAPSGVLVTCGLEQVLEALKLLLSPGGSGSSSLQNTKHDVLLQTLKSNLSALEAKFLKDAQWKKLKALRDELADKAEWPQSSEDITWSFTSQTLLLLLCLKEVLARLVADFNPGKPNPRTPEAAPALSPDTLSVSQQKTFQSVLQFVVTLGVCPYLIPGVGVPLRDRTEFGAVVQDVVRLEAAPHATRRLYICCRVLLDLAQHASLGSLIFCRHFGDIAAGLCQLGFCPTKRKPPGPVEEVLTEEERTLSRRALRDILDQVYQPLAVRELLTLQGGPRQPCTDVKTQLRCRAQAPAWLRRLCGQLLSERLMRPNGVQAVVRGILEGAGAGAAGGSDAEATAADWRKCDLIAKILASCPQQSLSPESYYKDICPQILDLFHLQDKLTARQFQRVATTTFITLSRERPELAAKYLLQPMLAPLQRCLSTAEIPESDMVPGAILVTEEELSRCVEDVFKVYVVANEPVPVLLDSLLPLLRVFFSLYCFTQQSVSHIRSLCQEILLWILVKLERKKAIASLKGFSGLDKTVPTLHPQCQFRAATHGGIVITAKEAISDDEDEALYQKVSSEQSQVEHLGDLLLHCQQCGLAGDFFIFCLKELSHLLEDREAEFTPKPSCYASLLELEHHQTLLIEDQERKLQVLQLLAVLCEKMSEQIFTHVTQVVDFVAATLQRACAGLAHEAESAVGSQTLSMSMGLVAVMLGGAVQLKSSDFAVLKQLLPLLERVSNTYPDPVIQELAADLRITISTHGAFSTDAVSTAAQSTLNQKDPGQKIEEQRQTSPDISTEGAQKPPRTGQGSSGPCTATSQPPGSITTQQFREVLLSACDPEVPTRAAALRTLARWVEQREARALEEQKKLLQIFLENLEHEDSFVYLSAIQGIALLSDVYPEEILVDLLAKYDSGKDKHTPETRMKVGEVLMRVVRALGDMVSKYREPLIHTFLRGVRDPDAAHRASSLANLGELCQCLHFLLGPVVHEVTACLIAVAKTDNDVQVRRAAVHVVVLLLRGLSQKATEVLSDVLRDLYHLLKHVVRLEPDDVAKLHAQLALEELDEIMRNFLFPPQKLEKKIVVLP
What are the official names of this protein?
Transport and Golgi organization protein 6 homolog, Transmembrane and coiled-coil domain-containing protein 7.
What is the protein family that this protein belongs to?
Belongs to the Tango6 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: AMT1_DICDI
Sequence: MVAGEIIKGVAAEITNGSSSSVVQKYLDCANQVAPDPGNTTWVLLSTILVLGMMPALAFFEAGLLRSKNTLSIITQIMSGIVVLTVMWQAFGYSLTFGPDQKGIIGNLDHAFLINVSYDDCSPNAPNIPAAAYAFFMMMFANITPLLMTGAFAERVKFKAFIALTVAWEIIVFYPVAHWIWGGGWLHKYFGVLDFAGGIVIHTSAGVSALVIALYVGRRKDFEKYGGEFPPSNLPLATIGAALLWMGWFGFNAGSALAAGNIATSAVASTQIGGSFSAIVWIILSAAKGKPNTVSVINGVIAGLAGITPASGYINSQYSIGLGICLGLASYYSVVLLKHKLHIDDALDVSSVHGLTGIIGSLAIGFCAELSVNPNGANGAFYGNPKLIGTQLLGVVSVAVWAAAWTWVLLKIIDATIGVKIDESEEELGLDLVEHGEFAYHNISLQGNENHYSSVINSHDFFK
What is the function of this protein?
Ammonium transporter that mediates the excretion of ammonium.  Controls ammonium homeostasis during growth and development.  Ammonium has been shown to function as a morphogen at multiple steps during the development.
What are the official names of this protein?
Ammonium transporter 1.
What is the protein family that this protein belongs to?
Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, phagosome membrane; Multi-pass membrane protein.
Protein: PSAB_POPTR
Sequence: MALRFPRFSQGLAQDPTTRRIWFGIATAHDFESHDDITEERLYQNIFASHFGQLAIIFLWTSGNLFHVAWQGNFETWVQDPLHVRPIAHAIWDPHFGQPAVEAFTRGGALGPVNIAYSGVYQWWYTIGLRTNEDLYIGALFLLFLSAVSLLGGWLHLQPKWKPSVSWFKNAESRLNHHLSGLFGVSSLAWTGHLVHVAIPGSRGESVRWNNFLDVLPHPQGLGPLFTGQWNLYAQNPDSSSHLFGTSQGAGTAILTLLGGFHPQTQSLWLTDMAHHHLAIAFLFLIAGHMYRTNFGIGHSIKDLLEAHIPPGGRLGRGHKGLYDTINNSLHFQLGLALASLGVITSLVAQHMYSLPAYAFIAQDFTTQAALYTHHQYIAGFIMTGAFAHGAIFFIRDYNPEQNEDNVLARMLDHKEAIISHLSWASLFLGFHTLGLYVHNDVMLAFGTPEKQILIEPIFAQWIQSAHGKTSYGFDVLLSSTNSPAFNAGRSIWLPGWLNAINENSNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAVFWMLNTIGWVTFYWHWKHITLWQGNVSQFNESSTYLMGWLRDYLWLNSSQLINGYNPFGMNSLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLAWAHERTPLANLIRWRDKPVALSIVQARLVGLAHFSVGYIFTYAAFLIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SLMA_HAEIN
Sequence: MVEEQLSLSGVEEIAPKIETPKIEKRTVKERRQQVLTVLIHMLHSERGMERMTTARLAKEVGVSEAALYRYFPSKTKMFEALIEHIESTLLSRITASMRNETQTMNRIHDILQTILDFARKNPGLTRVLTGHALMFEEAQLQARVAQFFDRLEMQFVNILQMRKLREGRAFNVDERIIASHLVTLCEGQFMRYVRTNFRLNSSQSFEQQWRFIEPLFA
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ILVC_JANMA
Sequence: MKVFYDKDCDLSLIKGKNVAIIGYGSQGHAHAQNLNDSGVKVTVGLRKGGASWDKVKNAGLNVAEVNDAVKAADVIMILLPDENIAQVYNENVAPYAKQGAVLAFAHGFNVHYGQVVPRADLDVIMIAPKAPGHTVRGTYSQGGGVPHLIAVYQDKSGVARDIALSYAMANGGGRAGIIETNFREETETDLFGEQAVLCGGAVELIKAGFETLTEAGYAPEMAYFECLHELKLIVDLIYEGGIANMNYSISNNAEYGEYVTGPKVVTEDTKNAMRQCLKDIQTGEYAKSFILENKAGAPTLISRRRLTAEHQIEEVGAKLRAMMPWIAKNKLVDQTKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: TADA_RICBR
Sequence: MREALKQAEIAFSKNEVPVGAVIVDRENQKIISKSYNNTEEKNNALYHAEIIAINEACRIISSKNLSDYDIYVTLEPCAMCAAAIAHSRLKRLFYGASDSKHGAVESNLRYFNSKACFHRPEIYSGIFAEDSALLMKGFFKKIRD
What is the function of this protein?
Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
What are the official names of this protein?
tRNA-specific adenosine deaminase.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: DPCKG_PYRNV
Sequence: MRCLRIRERRDLFAFPYPIAVWREPPRSLEVVSDLALSYGVEHIYTVGDVVTKNFLDYGVTPTSAAVDEKTRRGLPVEQHRKFQRVIKVVNPPGYITEEAWAAVEEAVGGGVLIKVEGEEDMLALAFIKMAPPRSLVVYGHYKGALIAVMVDWYRDAIDRLLQYLEKC
What is the function of this protein?
Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
What are the official names of this protein?
GTP-dependent dephospho-CoA kinase, Dephospho-coenzyme A kinase, DPCK.
What is the protein family that this protein belongs to?
Belongs to the GTP-dependent DPCK family.
Protein: CH10_BACFR
Sequence: MNIKPLADRVLILPAPAEEKTIGGIIIPDTAKEKPLKGEVVAVGHGTKDEEMVLKAGDTVLYGKYAGTELEVEGTKYLIMRQSDVLAVLG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB_XANAC
Sequence: MNAPVWWQQLLLAMTGGALGSGLRFAIGASLIQRFGNVFPWGTLTVNLLGSFVAGVLLVWLDARGPSSWPLRALLIVGVIGGLTTFSSLMMECLVFARTDRSTMIGIYLAVTLLAGLALVFAGARTGQWLVTR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KRA71_HUMAN
Sequence: MTRYFCCGSYFPGYPIYGTNFHGTFRATPLNCVVPLGSPLNYGCGCNGYSSLGYSFGGSNINNLGGCYGGSFYRPWGSGSGFGYSTY
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 7-1, High tyrosine-glycine keratin-associated protein 7.1.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 7 family.
Protein: YNFC_ECOBW
Sequence: MKYKLLPCLLAIFLTGCDRTEVTLSFTPEMASFSNEFDFDPLRGPVKDFTQTLMDEQGEVTKRVSGTLSEEGCFDSLELLDLENNTVVALVLDANYYRDAETLEKRVRLQGKCQLAELPSAGVSWETDDNGFVIKASSKQMQMEYRYDDQGYPLGKTTKSNDKTLSVSATPSTDPIKKLDYTAVTLLNNQRVGNVKQSCEYDSHANPVDCQLIIVDEGVKPAVERVYTIKNTIDYY
What are the official names of this protein?
UPF0257 lipoprotein YnfC.
What is the protein family that this protein belongs to?
Belongs to the UPF0257 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RSMH_STAAT
Sequence: MFHHISVMLNETIDYLNVKENGVYIDCTLGGAGHALYLLNQLNDDGRLIAIDQDQTAIDNAKEVLKDHLHKVTFVHSNFRELTQILKDLNIEKVDGIYYDLGVSSPQLDIPERGFSYHHDATLDMRMDQTQELTAYEIVNNWSYEALVKIFYRYGEEKFSKQIARRIEAHREQQPITTTLELVDIIKEGIPAKARRKGGHPAKRVFQALRIAVNDELSAFEDSIEQAIELVKVDGRISVITFHSLEDRLCKQVFQEYEKGPEVPRGLPVIPEAYTPKLKRVNRKPITATEEDLDDNNRARSAKLRVAEILK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1898_MYCTO
Sequence: MSVLVAFSVTPLGVGEGVGEIVTEAIRVVRDSGLPNQTDAMFTVIEGDTWAEVMAVVQRAVEAVAARAPRVSAVIKVDWRPGVTDAMTQKVATVERYLLRPE
What are the official names of this protein?
UPF0045 protein MT1949.
What is the protein family that this protein belongs to?
Belongs to the UPF0045 family.