PharMolix/UniProtQA huggingface dataset:
Protein: MIAB_SHEB9
Sequence: MSKKLHIKTWGCQMNEYDSSKMADLLGEYQGYTLTEEASEADILLLNTCSIREKAQEKVFHQLGRWKTLKDKNPNLIIGVGGCVASQEGKAIKDRAQCVDIIFGPQTLHRLPEMIEQVRRGDKAVIDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCSKYCSFCVVPYTRGEEVSRPSDDIILEIAQLAEQGVREVNLLGQNVNAYRGATHDGAICTFAELLRFVAAIDGIDRIRFTTSHPIEFTQDIIDVYEDTPELVSFLHLPVQSGSDRILTAMKRGHMAIEYKSIIRRLRKAREGIQISSDFIIGFPGETKEDFADTMKLIEDIGFDHSFSFIYSARPGTPAADLPDNVDMEEKKQRLAILQDRITQQAMRYSRHMMGTVQRILVEGPSVKNPMELRGRTENNRVVNFEGQPKHIGTFVDVEIVDVYTNSLRGVFIRGEDEMDLRRSLRPAEILAKRKQDDELGVTQFKP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OR59C_DROME
Sequence: MTKFFFKRLQTAPLDQEVSSLDASDYYYRIAFFLGWTPPKGALLRWIYSLWTLTTMWLGIVYLPLGLSLTYVKHFDRFTPTEFLTSLQVDINCIGNVIKSCVTYSQMWRFRRMNELISSLDKRCVTTTQRRIFHKMVARVNLIVILFLSTYLGFCFLTLFTSVFAGKAPWQLYNPLVDWRKGHWQLWIASILEYCVVSIGTMQELMSDTYAIVFISLFRCHLAILRDRIANLRQDPKLSEMEHYEQMVACIQDHRTIIQCSQIIRPILSITIFAQFMLVGIDLGLAAISILFFPNTIWTIMANVSFIVAICTESFPCCMLCEHLIEDSVHVSNALFHSNWITADRSYKSAVLYFLHRAQQPIQFTAGSIFPISVQSNIAVAKFAFTIITIVNQMNLGEKFFSDRSNGDINP
What is the function of this protein?
Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates.  The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration.  May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability (By similarity).
What are the official names of this protein?
Putative odorant receptor 59c.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family. Or2a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1220_ASPFU
Sequence: MHFSIGSLFLYLIASASCTAASPQYIQRSRRTPFTTSTSKPSAFTNPSTDTATTPYVLELTKINNKGNARSAVELNSQVRSGSANLVSFAEGVGFATSINIGNQTFEVVIDTGSSDLWVVRDGFICIDPVSRKEVAQSECRFGPAYAPNTTFHEVVGEFVDIKYADGEILSGVIGTENVTLAGITVNQTIGVMDYAGWYGDGVTSGLMGLAYSSLASAYTTNNRQPRLYNPIFATMYEQGLIDPIFSMVMNRNASNGTAAGYLTLGGLPPVDINGNFSTTPILITNIKGYPKDYDFYAVNIDGVALGNRSLPEAAGGIQYIIDSGTTLNYYPTPVADSVNAAFIPPAVYNDYDGAYVVDCNATASVHGVMIGGSTFYINPTDMILPGGMDNSGNKTCISGINAGGDVGQGIFVLGGTFLRNVVAVFDVGAAEMRFAASA
What is the function of this protein?
Probable aspartic-type endopeptidase which contributes to virulence.
What are the official names of this protein?
Probable aspartic-type endopeptidase AFUA_3G01220.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SGRR_ECOUT
Sequence: MPSARLQQQFIRLWQCCEGKSQETTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEENGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIANIVSPTPWTLDIHLTQPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNSTNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEGCYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHARTIKSEKPAGLESLTLTFYQDHSEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQHCIPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP
What is the function of this protein?
Activates the small RNA gene sgrS under glucose-phosphate stress conditions as well as yfdZ.  Represses its own transcription under both stress and non-stress conditions.  Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain.
What are the official names of this protein?
HTH-type transcriptional regulator SgrR.
Protein: YS95_CAEEL
Sequence: MQNIFENCSYHSKYEPYFLNCTNTTNQCVLIQDVGIIQAIDFWANLCIPFTLFVIAFILNGYYLSILIPEFRKMNDTTKKQYIFVVSRGISSLSASSIMMVLRLLKMLSTSFTVYFLFFLIDDLSFYSLLGSYVGSTLLLYLATVRPIFYSIQISVRIVYKFALVNVLLAVVLAVTTAIFQAAEVSDGFFHCDVQHCQPIINIAMFVIIATSFLIPIITLTFVLVTLCFQKSRTQSIGNFTVDNSVYKSARTRLAWTLFTFTLISLTEMIPSSFLVNLRVEDTITICVNFYQADHLFIPAIMNSFQTLAWGIALIVDPLCALLFDPRIRKVWVEHVSRLSIIIGRSFEACCHSNLNKEIQDK
What are the official names of this protein?
Putative G-protein coupled receptor B0244.5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. B0244 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SNX32_HUMAN
Sequence: METYAEVGKEGKPSCASVDLQGDSSLQVEISDAVSERDKVKFTVQTKSCLPHFAQTEFSVVRQHEEFIWLHDAYVENEEYAGLIIPPAPPRPDFEASREKLQKLGEGDSSVTREEFAKMKQELEAEYLAIFKKTVAMHEVFLQRLAAHPTLRRDHNFFVFLEYGQDLSVRGKNRKELLGGFLRNIVKSADEALITGMSGLKEVDDFFEHERTFLLEYHTRIRDACLRADRVMRAHKCLADDYIPISAALSSLGTQEVNQLRTSFLKLAELFERLRKLEGRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALADYENANKALDKARTRNREVRPAESHQQLCCQRFERLSDSAKQELMDFKSRRVSSFRKNLIELAELELKHAKASTLILRNTLVALKGEP
What is the function of this protein?
May be involved in several stages of intracellular trafficking.
What are the official names of this protein?
Sorting nexin-32, Sorting nexin-6B.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
Protein: MATK_THUDO
Sequence: MDEFXXNSNKNRXWQQFFXYPLFFREDLXAIXHDHHLDRFGSSEPKEIXVXNFXSFLTVKRSIRRICKQNKSISLFGNSDSNKLIEYNKNFSFKSMLEGFTIVLEVSIAMRSKHFIKGMDGWNSLRSIHCIFPFMEDKLPHSNYISDIRVPYSIHPEILVRIFRRWIRDVPSLHLLRSILHEWKNSFSRENLEKVLITQRENTRFSLFLWNSYVYECESFLIPLIKRFFNSQSLLYGSFPDRTHFEKKIKDIVIFPLHKISTKKIWLLKDSFIHYVRYGERSLIALKGTHLQVKKCRYHLFHFWQYFFHLWFQPYRICSLELSKTSFSFLGFFIHVKMRPLVVRAKMLDDLFITDLITNELNPIAPIRSILFSLAKEKFCDISGWPISKLSWTSLSDDDIXDRFDRIWINLFHYYSGSINQDGLYHIKYILLLSCAKTLACKHKSTIRVVREQLGSELFTKSFSKEREFISSSFSKTRSQRERIWNSEISQRNPLXXLWQKMENKQIEN
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MNME_BARQU
Sequence: MDTIFAVSSGLLPSGVAVIRLSGPHVINIVKALCGHLPKARLMHYGNLTARDGSFLDSALTVFFPAPHSFTGEDCAEFHLHGSKAVVNRFLDELSTFDGCRSAEAGEFSRRAFMEGKLDLIQAESLADLIEAETESQRRLAVMGTSGRLTTLYRDWRNRLIKARAFIEAELDFSDEADVSDLISDKVWEDVEELCISIRDHIAQGERANILRDGLKIVIAGAPNSGKSSIMNRLAGKSVAIVMEEAGTTRDALEIRLVLGGLPVFLTDTAGLRETENKIEQLGIEIAKQHIVDADLVILVYDMGNPKEVNLPETSAEIWHVGNKLDLYEEENKKTWTIQFSALTGLNFDYFIKELESFCLRRVSEIGNLFPARKRQLQLLKEAIREIEASINYRSLDLSLHAEHLRCASVFLGKITGDIDVEDLLDIIFSEFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_BEII9
Sequence: MAKRDFYEVLGVTKTCTEAEMKVAFRKAAMQWHPDRNPGNEEAEIQFKEINEAYQTLSDGQKRAAYDRYGHAAFEHGGGGNDGFASSMADIFDDLFGDVMGRRGGRNGPARGSDLRYNMEITLEEAFQGKLASLTLPTSITCEACDGTGAKAGAKPRICPTCGGQGRVRAQQGFFAIERTCPQCHGRGEIIDDPCQACGGAGRVTRERTLSVNIPPGVEDGTRIRLAGEGEAGTRGGPAGDLYIFVSTKPHPFFQRDGADLFCRVPISMTQAALGGEVTVHTIDGKEAKVKISEGTQSGKQFKLKNKGMPVLRSREVGDLYIQATVETPQNLTKRQRELLAEFDAESSNKTHPEASGFFARMKDFFENLSGQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM163_HUMAN
Sequence: MEPAAGIQRRSSQGPTVPPPPRGHAPPAAAPGPAPLSSPVREPPQLEEERQVRISESGQFSDGLEDRGLLESSTRLKPHEAQNYRKKALWVSWFSIIVTLALAVAAFTVSVMRYSASAFGFAFDAILDVLSSAIVLWRYSNAAAVHSAHREYIACVILGVIFLLSSICIVVKAIHDLSTRLLPEVDDFLFSVSILSGILCSILAVLKFMLGKVLTSRALITDGFNSLVGGVMGFSILLSAEVFKHDSAVWYLDGSIGVLIGLTIFAYGVKLLIDMVPRVRQTRHYEMFE
What is the function of this protein?
May bind zinc and other divalent cations and recruit them to vesicular organelles.
What are the official names of this protein?
Transmembrane protein 163.
What is the protein family that this protein belongs to?
Belongs to the TMEM163 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Early endosome membrane. Note=Glutamatergic synaptic vesicles.
Protein: SYP_ACIBS
Sequence: MRTSRFLFATLRETPNDAEVISHQLMLRAGMIRKLASGLYTWLPMGTRVLKKVDAIVREEMNRSGAMEVFMPVTQPASLWEESGRYEQYGPGLLRFKDRHDNPFVLGPTHEEVITDLARNELKSYKQLPVNFYQIQTKFRDEIRPRFGVMRSREFIMKDAYSFHATQESLQETYNVMYDTYSRIFTRLGLDFRPVQADTGSIGGSASHEFHVLAASGEDDIAFSTESDYAANVEMAEAVLVGERAAPTQEFKLVETPNQKTIADVCQFLNADPKQSVKALLVQGVADEKGNVPVVALFLRGDHELNEIKAEKHPLVAAPLAFATEEQLQAFGLTAGFTGPQGLVEKGITVIVDRAASVLSDFVAGANEADKHAVGVNWERDAQITEVFDLRNVVEGDPSPDGKGTLQIKCGIEVGHIFQLGTKYSEALGCKVLGEDGKPFTVTMGCYGIGVTRVVAAAIEQNYDDKGIIWPQAIAPFEIAIVPMNAHKSPRTLEAAEALYAELQAQGFDVLLDDRNERPGVKFSDLELMGIPHRIVIGEKGLDAGTFEYKGRRDAEASNLTKEELLAKLAR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMY1B_HUMAN
Sequence: MKLFWLLFTIGFCWAQYSSNTQQGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPPNENVAIHNPFRPWWERYQPVSYKLCTRSGNEDEFRNMVTRCNNVGVRIYVDAVINHMCGNAVSAGTSSTCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLSGLLDLALGKDYVRSKIAEYMNHLIDIGVAGFRIDASKHMWPGDIKAILDKLHNLNSNWFPEGSKPFIYQEVIDLGGEPIKSSDYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWPRYFENGKDVNDWVGPPNDNGVTKEVTINPDTTCGNDWVCEHRWRQIRNMVNFRNVVDGQPFTNWYDNGSNQVAFGRGNRGFIVFNNDDWTFSLTLQTGLPAGTYCDVISGDKINGNCTGIKIYVSDDGKAHFSISNSAEDPFIAIHAESKL
What is the function of this protein?
Calcium-binding enzyme that initiates starch digestion in the oral cavity (PubMed:12527308).  Catalyzes the hydrolysis of internal (1->4)-alpha-D-glucosidic bonds, yielding a mixture of maltose, isomaltose, small amounts of glucose as well as small linear and branched oligosaccharides called dextrins (PubMed:12527308).
What are the official names of this protein?
Alpha-amylase 1B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DABA_METS4
Sequence: MIEIVHSLPTPHDAVRAAADGAGRLIPPLWPLASSVAVNPFLGHTGEPLWAAGARLGRASGAAVTMPRSWYRDRIAAGSITDEDLLDALADAPADLRPADLGALRGAAALDPEPVRPLPTVASLCAEASGIDWPGLIADRLGAWAAGHFDEGQALWAAPSGGSTLALWRAWAIHDLTPEIAGLGGFARHVSEVPDGALPALARAVCGLGLSPGALESYFHQILLSLGGWAQYARYKLWQAELAGGTDGTLRDLLAVRVIWDEALLTRYGERIAESWAAVAAAHASPARPTRDLVIDSILQDAAERAAQRALAATLAATLAGGSPGVGESRPALQAAFCIDVRSEVFRRALESLDPGIRTLGFAGFFGLATAHRRFASDIAERRLPVLLNPGLRTCAGGPALSDADHASRLAARARRAWGRFRQAAVSSFAFVEAAGPLYAAKLLGDSLHLGGPATPHDPMPRLDPPRDLASRVATADAVLRAMSLTSTFAPIVLLVGHGANVVNNPHASALHCGACGGYSGEVNARLLAQLLNDADVRAGLRERGLEVPADTVFLAGLHDTTTDEVTLYAGDLPGGSPLQGLEPVRVWLAQAGKLARAERALRLPRARDNASVVRRSRDWAETRPEWGLAGCNAFIAAPRHRTAGQPLHGRAFLHDYDWQRDEGFGVLELIVTAPVVVASWISLQYYGSTVAPELFGSGNKLLHNVVGGIGVLEGNGGPLRAGLPRQSVHDGEHHAHEPLRLSVLIEAPRQAITDVLERHREVRALFDNRWLHLFALDQDGRMAWRYAGDLRWTSTAASDGAVPGLPLRAAV
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: BLI1_YEAS1
Sequence: MGEQNKLYYDVEKLVNSLQESFDLDCAQSVSLFTSKSRSNEAWLEELENKFKLKDDVELDDVENLRAEIDMKLNMLEDKVSYYERLYKELEEFQNEIKIKTVVNNRRQSRTPK
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit BLI1, BLOC-1 subunit BLI1, BLOC-1 interactor 1.
What is the protein family that this protein belongs to?
Belongs to the BLI1 family.
What are the subcellular locations of this protein?
Endosome.
Protein: RL5_SHEON
Sequence: MAKLHDKYQETVVAELTQKFGYTSVMQVPRIEKITLNMGVGEAVADKKVMEHAVRDMTAIAGQKPVVTVARKSVAGFKIREGYPIGCKVTLRGERMWEFLERLVDIAIPRIRDFRGLSAKAFDGRGNYAMGVREQIIFPEIDYDKIDKIRGMDIVITTSAKTDEEGRALLDAFNFPFKK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: ATPA_PONAB
Sequence: MLSVRVAAAVVRALPRRAGLVSRNALGSSFIAARNFHASNTHLQKTGTAEMSSILEERILGADTSVDLEETGRVLSIGDGIARVHGLRNVQAEEMVEFSSGLKGMSLNLEPDNVGVVVFGNDKLIKEGDIVKRTGAIVDVPVGEELLGRVVDALGNAIDGKGPISSKTRRRVGLKAPGIIPRISVREPMQTGIKAVDSLVPIGRGQRELIIGDRQTGKTSIAIDTIINQKRFNDGSDEKKKLYCIYVAIGQKRSTVAQLVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCSMGEYFRDNGKHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDAFGGGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTRAMKQVAGTMKLELAQYREVAAFAQFGSDLDAATQQLLSRGVRLTELLKQGQYSPMAIEEQVAVIYAGVRGYLDKLEPSKITKFENAFLSHVVSQHQALLGTIRADGKISEQSDAKLKEIVTNFLAGFEA
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Subunits alpha and beta form the catalytic core in F(1).  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.  Subunit alpha does not bear the catalytic high-affinity ATP-binding sites (By similarity).  Binds the bacterial siderophore enterobactin and can promote mitochondrial accumulation of enterobactin-derived iron ions (By similarity).
What are the official names of this protein?
ATP synthase subunit alpha, mitochondrial, ATP synthase F1 subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Cell membrane; Peripheral membrane protein; Extracellular side. Note=Colocalizes with HRG on the cell surface of T-cells.
Protein: LAN2G_RUMFL
Sequence: MNNNNFDMEKFKKLAAIVSEGEIDEMLDETTVGAASTLPCAEVVVTVTGIIVKATTGFDWCPTGACTHSCRF
What is the function of this protein?
Lanthionine-containing peptide antibiotic (lantibiotic) that is probably weakly active on Gram-positive bacteria, since its analog [Del1]Flvbeta. g shows weak antibacterial activity against M. luteus (PubMed:27028884).  This activity is synergistically enhanced by [Del2]Flvalpha. a, an analog of Flvalpha. a, which is encoded by the same operon than Flvbeta. g (PubMed:27028884).  The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores (By similarity).
What are the official names of this protein?
Lantibiotic Flvbeta.g.
What are the subcellular locations of this protein?
Secreted.
Protein: PETG_SYNS3
Sequence: MIEPLLCGIVLGLIPITLMGLFVAAWNQYRRGSALEG
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: CUSA_ECOL6
Sequence: MIEWIIRRSVANRFLVLMGALFLSIWGTWTIINTPVDALPDLSDVQVIIKTSYPGQAPQIVENQVTYPLTTTMLSVPGAKTVRGFSQFGDSYVYVIFEDGTDPYWARSRVLEYLNQVQGKLPAGVSAELGPDATGVGWIYEYALVDRSGKHDLADLRSLQDWFLKYELKTIPDVAEVASVGGVVKEYQVVIDPQRLAQYGISLAEVKSALDASNQEAGGSSIELAEAEYMVRASGYLQTLDDFNHIVLKASENGVPVYLRDVAKVQVGPEMRRGIAELNGEGEVAGGVVILRSGKNAREVIAAVKDKLETLKSSLPEGVEIVTTYDRSQLIDRAIDNLSGKLLEEFIVVAVVCALFLWHVRSALVAIISLPLGLCIAFIVMHFQGLNANIMSLGGIAIAVGAMVDAAIVMIENAHKRLEEWQHQHPDATLDNKTRWQVITDASVEVGPALFISLLIITLSFIPIFTLEGQEGRLFGPLAFTKTYAMAGAALLAIVVIPILMGYWIRGKIPPESSNPLNRFLIRVYHPLLLKVLHWPKTTLLVAALSVLTVLWPXNKVGGEFLPQINEGDLLYMPSTLPGISAAEAASMLQKTDKLIMSVPEVARVFGKTGKAETATDSAPLEMVETTIQLKPQDQWRPGMTMDKIIEELDNTVRLPGLANLWVPPIRNRIDMLSTGIKSPIGIKVSGTVLADIDTMAEQIEEVARTVPGVASALAERLEGGRYINVEINREKAARYGMTVADVQLFVTSAVGGAMVGETVEGIARYPINLRYPQSWRDSPQALRQLPILTPMKQQITLADVADVKVSTGPSMLKTENARPTSWIYIDARDRDMVSVVHDLQKAIAEKVQLKPGTSVAFSGQFELLERANHKLKLMVPMTLMIIFVLLYLAFRRVGEALLIISSVPFALVGGIWLLWWMGFHLSVATGTGFIALAGVAAEFGVVMLMYLRHAIEAEPSLNNPQTFSEQKLDEALYHGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGMITAPLLSLFIIPAAYKLMWLHRHRVRK
What is the function of this protein?
Part of a cation efflux system that mediates resistance to copper and silver.
What are the official names of this protein?
Cation efflux system protein CusA.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VEMP_CVCBG
Sequence: MTFPRALTVIDDNGMVISIIFWLLLIIILILFSIALLNIIKLCMVCCNLGRTVVVIPVRHAYDAYKNFMRINAYNHNEALLV
What is the function of this protein?
Plays a central role in virus morphogenesis and assembly.  Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport.  Also plays a role in the induction of apoptosis.
What are the official names of this protein?
Envelope small membrane protein, E protein, sM protein.
What is the protein family that this protein belongs to?
Belongs to the alphacoronaviruses E protein family.
What are the subcellular locations of this protein?
Host Golgi apparatus membrane; Single-pass type III membrane protein. Note=The cytoplasmic tail functions as a Golgi complex-targeting signal.
Protein: YJ16_PYRHO
Sequence: MKIRRYLVPNLIAWSIGIAWLIPFMGVLMASVRPYEEIVSGWWHLHPFTITLKNYINALNHPMFPIGEGLKNSLIVAIPSTIVPVIVASLAAYAFARYSFPIKHYLFAFIVLLMALPQQMTVVPLYFLLRNAHLLNTFRGLIIVHSAWGLAWIIFFMRNYFSMLPTDVEEAAKIDGATDFQIFYKIVLPMALPGLISASILQFTWVWSDFFLALVFLQNPEKYVATQRLPLLRGQYFVDWGLLTAASIMVMLVPLLVYALFQKYYISGMIGWSVEK
What is the function of this protein?
Probably part of a binding-protein-dependent transport system PH1036/38/39.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Probable ABC transporter permease protein PH1036.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: APT_PROM3
Sequence: MDLRHLIQDIPDFPKPGILFRDISPLLRDPDGWGEVMRQLGDLCTEFKPDLIVGIESRGFIVGTALATNRKIGFVPVRKPGKLPGDVLGIDYSLEYGSDRLEIHADALQGHPRVLMVDDLLATGGTAKATVELIEQAGGDLVGCGFVIELAALGGRQQLPVEIPVKSLIIYS
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIKD_BRUSU
Sequence: MTRKTLAIEGLTATTVIDGQQRVLVDNLSLGVQRGRILALVGASGSGKSMTCSAALGVLPPGVTASRGRVTIDGVPYAANALRGRHVATIMQNPRGAFNPVRTMRDHAIETLQALGKLSSNPQDQIVHCMRAAGLEDVKTILSLHPFEMSGGMLQRMMIALALLSEAPFLFADEPTTDLDLVVQLRVLELLEKLVEERDLGILLVTHDMGVVARLAHDVAVLDHGRLIEQAPVMDIFQTPGHEVTRMLVSAHLSLYGMELNA
What is the function of this protein?
Part of the ABC transporter complex NikABCDE involved in nickel import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Nickel import ATP-binding protein NikD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL7_STAAC
Sequence: MANHEQIIEAIKEMSVLELNDLVKAIEEEFGVTAAAPVAVAGAAGGADAAAEKTEFDVELTSAGSSKIKVVKAVKEATGLGLKDAKELVDGAPKVIKEALPKEEAEKLKEQLEEVGATVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.