PharMolix/UniProtQA huggingface dataset:
Protein: SECY_LACLA
Sequence: MFFKTLKEAFKVKDVRARILFTIFILFVFRLGAHITVPGVNVQNLTEVSNLPFLNMMNLVSGNAMQNYSLFAMGVSPYITASIIVQLLQMDILPKFVEWSKQGEIGRRKLNQATRYITLVLAMAQSIGITAGFQAMSSLNIVQNPNWQSYLMIGAILTTGSMVVTWMGEQINEKGFGSGVSVIIFAGIVSSIPSAVKSVYDEKFLNVRPSEIPMSWLFVIGLVLSAIIIIYVTTFVQQAERKVPIQYTKLTQGAPTSSYLPLRVNPAGVIPVIFAGSITTAPATILQFLQRSQGSNVGWLSTLQDALSYTTWTGMLFYALLIVLFTFFYSFVQVNPEKMAENLQKQGSYIPSVRPGKGTEKYVSRLLMRLATVGALFLGLISIIPIAAQNVWGLPKIVALGGTSLLILIQVAIQAVKQLEGYLLKRKYAGFMDNPLETK
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RUVB_ECOL6
Sequence: MIEADRLISAGTTLPEDVADRAIRPKLLEEYVGQPQVRSQMEIFIKAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEFYQVPDLQYIVSRSARFMGLEMSDDGALEVARRARGTPRIANRLLRRVRDFAEVKHDGTISADIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMATVRAWNHFGITPPEMP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: PSIE_DICDI
Sequence: MKLISVLITFLLATVIYSQTSPATLKFTVQVYDQFPGFNNNFEPGLGNAITGLIKSTLNSTSRVPELVSTEARIVKNINGGIINPSLFPYFFSPQQDSSLPGQNSPLSLDLIFTYDTTRKIYVYDNQNFFPIDNQGFDVDPAKRIYLNEKKTYHNYHFCMKMNTVFTYKGYEVFNFRGDDDVWVFINNKLVIDLGGLHSPIGTSVDTMTLGLTIGNSYNFDLFFCERHTVGSTIKIETNLLFYCPFKDYCGVCQGDGSSCCNPLTTCNDNNQCTIDSCPSANTIIGPGSIPNYCFHTPKINTNPIDICFNYQCNSSTGNFDPIPIPCLDRSSECLSTIGCNSTVGCQYESICNSNVCNIQNQCSSNGTCVPKSSNDCGIELDGQVDKCKIYSCDSNGGVGCIKEDKCKPSSNPCISTQCNATNGQCYETQIPGDICDCGCGIPENKCKVSWCTPEGICQPKFKSEIDDNNSCTLDSCDPCTGIISHMTAPQCLSCNQCSN
What are the official names of this protein?
Protein psiE.
What is the protein family that this protein belongs to?
Belongs to the prespore-cell-inducing factor family.
What are the subcellular locations of this protein?
Secreted.
Protein: IOLE_BACSU
Sequence: MGKNEILWGIAPIGWRNDDMPEIGAGNTLQHLLSDIVVARFQGTEVGGFFPEPAILNKELKLRNLRIAGKWFSSFILRDGLGEAAKTFTLHCEYLQQVNADVAVVSEQTYSVQSLEKNVFTEKPHFTDDEWERLCEGLNHLGEIAAQHGLKLVYHHHLGTGVQTAEEVDRLMAGTDPAHVHLLYDTGHAYISDGDYMGMLEKHIGRIKHVHFKDARLNVMEQCRLEGQSFRQSFLKGMFTVPGDGCIDFREVYQLLLKHSYSGWIVIEAEQDPDVANPLEYALIARNYIDQQLLDLA
What is the function of this protein?
Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).
What are the official names of this protein?
Inosose dehydratase, 2-keto-myo-inositol dehydratase, 2KMI dehydratase.
What is the protein family that this protein belongs to?
Belongs to the IolE/MocC family.
Protein: COAX_MYCGI
Sequence: MLLAIDVRNTHTVVGLISGSGSHGKVEHHWRIRTESEVTADELALTIDGLIGDDAELLTGAAGLSTVPSVLHEVRVMLEQYWPSVPHVLIEPGVRTGIPLLVDNPKEVGADRIVNCLAAYQKYGSAAIVVDFGSSICVDVVSAKGEFLGGAIAPGVQVSSDAAAARSAALRRVELTRPRSVVGKNTVECMQAGAVFGFAALVDGLVNRIREDVDGFGGDDVTVVATGHSAPLVLEDLSTVQHYDRHLTLDGLRLVFERNRDNQRKLKQAR
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEXMI_RAT
Sequence: MDNQQDKVIAASANGENNLINGVKENDSEEQDVAMKSFAALEASTPIQPIPVVQKESPMFPRGLLPLPSKKPCMQSPPSPLGLIEAPDHSATGASVNAISLTSGVAKGLNTWSLPNECEKAPFAIMEPAGISALNGDCLMQPSRTCLGCFMESKEAVDPEPGISLKVGDLNRDYETCAVSDIGIQCINAGENLKYGEQLLSDQLLGFPLHKSRAGDRRESEKPDIDLEDPTQKSYYEALLLDKCNTEEALLANSNQDWGYFETFISESKIELLDLCSKNELSVNLFSEEDVENYMFDDDESTLGSDVCSLKIRYESFQDNVRDKTTLLMQEDAQFNFFPSVFTTCPKRESKSGVLKQSSDLSQFKVPDVSIIWGDEDKNLDKKKGKEEVHEDKSIEKKDEKDNGEKPALNNKPCSGLEVEQFKNLKPDHLTNSLETSGNFSDDSSFIEVSYDAMGEIKDCSRYMARDTNSGSSSSQQNYGLRAKRKVRYSEDYLYDVDSLEGEKVNERKEWPPGGSKEEDDDEWCPKKRRKVTRKEPPVIIKYIIINRFKGEKNMLVKLGKVDASETTVNLSESQLSKYAKLSPLKGFWQKKKKQKNGNTDSVKTPFCQKQSFEPGSFEVSFLPPARKRKSKLGNRHRIQRIQSMEASASSKQVSFGSDQKQASNRKEEGGLKGTPKSALLAAPSSANGSHLRGLIGPDSAKVKAQDTEFKGPERKVLNKIKFKSEARLKSKKIKTGQENKPVVQMSPVSEDPSSKANLKNEVTPGTSNSSHMSEFHETKVVKNSTFLPTTCSSEMPLSSANVATNIPVIPGGYLQTLLDASDLSNNTSISYFTNHSAEQNEASLSQTEKAFAPLQSAQDCVLSSSSDSQLQQSSQNFKMEASNYGSLWPDKDTSGSQEFMTEVSGEIATSQSSEFEATQVVSMENNLTAITYSPVCLNSGGSGCNKVLYASVQDSHLAPDDSYQLCHFNNGEICFPFQQGPISTEDDGQLFSFDSMTPLSVSSSSYCPLSLKSCEKDGDDDINDDFLAHCSPKLVIQQSIDEIAPLKESTDLLDISNFTPDKFRHSSLSEMSPPDTPSLSPQSTRCESIKTLGTMKGFQEGVPGSLSSMEKIKWDCSTLSQQVQADDGFTLNNHQFQFHMFNDEDSVGLLQKNPCLSTFDEPAGQISANNKVSKSRKKTSPGKSGAVSQSSSQKNTRKKSPKASNKGVEKPPSKTSRQVPKSAKKGKYVAAVNGEKMQIGIGHSGGQPNSTSSNGKTLTECIQHGGPVAPMKIPSQKGLSGDWALGKESRPGWNDMSVVTNTNNLLDDDQREFQEPSYILSNIASGMADVQRFMMASMEPLWEPMEHQGESNTFYSPDSNSLKLKTLKILAGTPQESKKKINNGSSGATKNHRSIKAVSKSSGKAAVGDPGHADVSGSSEDSRSAFFDKKYSNMNTLGNNGPTHKKLYRHKSSSKTLRDEKYKGKRVEREQIHKDEAGTTCFEKLRGSSYNLLKAETAFGVLPVFEEETHIFQKDI
What is the function of this protein?
Involved in neurite outgrowth by regulating cell-cell adhesion via the N-cadherin signaling pathway (PubMed:23615299, PubMed:22531377, PubMed:24071057, PubMed:27822498).  May act by regulating expression of protein-coding genes, such as N-cadherins and integrin beta-1 (ITGB1) (PubMed:24071057, PubMed:27822498).
What are the official names of this protein?
Neurite extension and migration factor, KIAA2022 protein associated with intellectual disability, language impairment and autistic behavior homolog, KIDLIA, XLMR protein related to neurite extension, Xpn.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: NUOD_RHILO
Sequence: MAETSVRNFNINFGPQHPAAHGVLRLVLELDGEVVDRVDPHIGLLHRGTEKLIEAKTYLQAVPYLDRLDYCAPMNQEHAFALAAERLLGIEVPKRGQLIRVLYCEIGRIMSHILNVTTQAMDVGALTPPLWGFVEREKLMVFYERASGSRMHAAYFRPGGVHQDLPRQLVEDIGKWIDPFLKSIDDLDRLLTGNRIFKQRNVDIGIVSLADAWAWGFSGVMVRGSGAAWDLRKSQPYECYSEMDFDIPIGKNGDCYDRYLVRMEEMRQSARIMRQCVDLLLGKESTGPVSNLDGKVVPPKRAAMKRSMEALIHHFKLYTEGYRVPAGEVYAAVEAPKGEFGVYLVSDGTNKPYRCKLRAPGFAHLQAMDFLCRGHLLADVTAVLGSLDIVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CMTA1_ARATH
Sequence: MVDRRSFGSITPPLQLDMEQLLSEAQHRWLRPTEICEILQNYHKFHIASESPTRPASGSLFLFDRKVLRYFRKDGHNWRKKKDGKTIREAHEKLKVGSIDVLHCYYAHGEANENFQRRCYWMLEQHLMHIVFVHYLEVKGNRTSIGMKENNSNSVNGTASVNIDSTASPTSTLSSLCEDADTGDSQQASSVLRPSPEPQTGNRYGWTPAPGMRNVSQVHGNRVRESDSQRLVDVRALDTVGNSLTRFHDQPYCNNLLTQMQPSNTDSMLVEENSEKGGRLKAEHIRNPLQTQFNWQDDTDLALFEQSAQDNFETFSSLLGSENLQPFGISYQAPPSNMDSEYMPVMKILRRSEDSLKKVDSFSKWAIKELGEMEDLQMQSSRGDIAWTTVECETAAAGISLSPSLSEDQRFTIVDFWPKSAKTDAEVEVMVIGTFLLSPQEVTKYNWSCMFGEVEVPAEILVDGVLCCHAPPHTAGHVPFYVTCSNRFACSEVREFDFLSGSTQKINATDVYGTYTNEASLQLRFEKMLAHRDFVHEHHIFEDVGDKRRQISKIMLLKEEKEYLLPGTYQRDSTKQEPKGQLFRELFEEELYIWLIHKVTEEGKGPNILDEDGQGILHFVAALGYDWAIKPVLAAGVNINFRDANGWSALHWAAFSGREETVAVLVSLGADAGALTDPSPELPLGKTAADLAYANGHRGISGFLAESSLTSYLEKLTVDSKENSPANSCGEKAVQTVSERTAAPMTYGDVPEKLSLKDSLTAVRNATQAADRLHQVFRMQSFQRKQLCDIGDDEKIDISDQLAVSFAASKTKNPGQGDVSLSCAATHIQKKYRGWKKRKEFLLIRQRIVKIQAHVRGHQVRKQYRTVIWSVGLLEKIILRWRRKGNGLRGFKRNAVAKTVEPEPPVSAICPRIPQEDEYDYLKEGRKQTEERLQKALTRVKSMVQYPEARDQYRRLLTVVEGFRENEASSSASINNKEEEAVNCEEDDFIDIESLLNDDTLMMSISP
What is the function of this protein?
Transcription activator that binds calmodulin in a calcium-dependent manner in vitro (PubMed:11925432).  Binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3' (By similarity).  Regulates transcriptional activity in response to calcium signals (Probable).  Involved in freezing tolerance (PubMed:19270186).  Involved in freezing tolerance in association with CAMTA2 and CAMTA3.  Contributes together with CAMTA2 and CAMTA3 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:23581962).  Involved in drought stress responses by regulating several drought-responsive genes (PubMed:23547968).  Involved in auxin signaling and responses to abiotic stresses (PubMed:20383645).  Activates the expression of the V-PPase proton pump AVP1 in pollen (PubMed:14581622).
What are the official names of this protein?
Calmodulin-binding transcription activator 1, AtCAMTA1, Ethylene-induced calmodulin-binding protein b, EICBP.b, Signal-responsive protein 2, AtSR2.
What is the protein family that this protein belongs to?
Belongs to the CAMTA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PRMA_SULNB
Sequence: MQDKYYELTITLDDQYVDLISDYIMNIHDEGLEFATGKIVMRSESDLTFVKDALVALQDELESDIHMDFNLEEKENIDWIKSYQESIQPIEAGKFYIFPSWYEPKEGYINIKIDPALAFGSGHHATTFSCLEAISKTVKAGDRVVDVGCGSGILGLAAKKLGATVELCDTDPLSVESCKENFKLNEAQYDELWEGSIDKAVGTYDVVIANIIADVLRFISRDLKAAVQEGGYLILSGILDKKEELVKASFQDLTLEKRTLKDEWVTLVYKKEKING
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK16_ORYSJ
Sequence: MLSPKRTRFRKQHRGRMKGKSYRGNCICFGRYALQALEPTWITARQIEAGRRAMTRYARRGGKIWVRIFPDKPVTIRPTETRMGSGKGSPEYWVAVVKPGRILYEMGGVSETVARAAISIAASKMPIRSQFLRLEI
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ERPA_PSESM
Sequence: MSVESFTPTALEFTPNAAHKVKTLVDEEGNDRLKLRVFVTGGGCSGFQYGFTFDEDVADDDTIVEREGVSLVVDPMSFQYLAGAEVDYQEGLEGSRFVIKNPNASTTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: YME1_SCHPO
Sequence: MSRVLHPIFLFGKTSFLYSGCSKFGGRLFNNSIVHGWLRTRSYALASGLHPLRKQKLAHFEDLANANMSDPYMQAKLYKELADNFPEAIISRYETQGVARNSACDRYYQEALRKKSWSRSLSNNISLSQSSSSPATSSFSDPKAFSAGVPKFTSDTSSTVSSTPSLNHSLQNSMPPSTPTPPPVWAPTIVSSALGTSSKTPVYVVVDEPRFTKFFRIFKFIAGLSVASYFVLLGMSIFAETSGLNNIMTNTTEQEPMEERAINVRFSDVQGVDEAKEELEEIVDFLRDPTHFTRLGGKLPRGVLLTGPPGTGKTMLARAVAGEANVPFFFMSGSQFDEMYVGVGAKRVRELFAAARKQAPSIIFIDELDAIGQKRNARDAAHMRQTLNQLLVDLDGFSKNEDLAHPVVFIGATNFPESLDPALTRPGRFDRHIHVPLPDVRGRLAILLQHTRHVPLGKDVDLSIIARGTSGFAGADLANLINQAAVYASKNLSTAVSMRDLEWSKDRILMGAERKSAFITPENKLMTAYHEGGHALVALFTKNAMRPYKATIMPRGSSLGMTISLPDMDKDSWTREEYLAMLDVTMGGRAAEELLYGKDKITSGAHNDIDKATQVARRMVTEFGMSDRIGPVSLEAEMDNLSPATRALVESEIKSLLEASYERSLSLLKSHKKELDALATALVDYEFLTAEEMNRVVKGDRDLLRNKLS
What is the function of this protein?
Putative ATP-dependent protease.
What are the official names of this protein?
ATP-dependent zinc metalloprotease YME1 homolog.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: ISPF_ACIB5
Sequence: MVAQIRIGQGMDVHAFEEGNFVTLAGVQIPHTHGLKAHSDGDVVLHALCDALLGALALGDIGQHFPDTDPEFKGADSRVLLKHVYQLILDRGYHLNNADITVACERPKLAKYNLEMRQSIADVLNVDLNQISIKATTTEKLGFTGRQEGILATATVLISH
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: LNP1_CAEEL
Sequence: MGNLFSRNKSPATELERVALSIDDLKKRLQTISSSNTNTLYYYYMSIVVILSIAMAHTWLRFEDPQKTYVACALMLGAIGIVLAGRYVINGFFSWRTNRTTQKLENAISQKTTLLDLVKETLKFKEAKEILDRYEKIEQNTTIDKNDSTLKSPSPIKKLTADSSMFATPKQEQKRVETPTAQGPNSAMNSMNMTPYHQRNRNAVPIRPFLRQTTAFDRVLDYFMSDGPNCRNALICSICHTHNGMSTPAEYPYISFRCFECGHLNPAKKMGPQIPLTRPPMGPKGIQHNGRVGPSENTHNMMENQKPSTDLTPSASQNGSEKGSDSENEKVPESKTMETEFH
What is the function of this protein?
Plays a role in tubular endoplasmic reticulum network formation and maintenance (By similarity).  May be involved in central nervous system development.  Has a presynaptic role in neurotransmission.  Likely to operate in synaptogenesis by regulating vesicular transport or localization.  Required for correct localization of rab-3 and snb-1.
What are the official names of this protein?
Endoplasmic reticulum junction formation protein lunapark-1, ER junction formation factor lunapark.
What is the protein family that this protein belongs to?
Belongs to the lunapark family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localizes to three-way ER tubule junctions.
Protein: RL331_STRCO
Sequence: MARNELRPVIKLRSTAGTGYTYVTRKNRRNDPDRLVLRKYDPAAGRHVDFREER
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: ENGB_SHEB5
Sequence: MTESRIDFRRAKFLISAPDIAHLDQYLPGDVGVEIAFAGRSNAGKSSALNALTEQKSLARTSKTPGRTQLINVFELDAQRRLVDLPGYGFAQVPLALKNKWQQALGEYLQKRACLSGVVVLMDIRHPLKDLDMQMIEWAVASEIPVLALLTKSDKLAQSAKMKTVNEVRLALSEFGDWVQVEPFSSLKGTGKPKVLAILNEWCHPQWLTDELDAANNAE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: HIGA1_VIBCH
Sequence: MRKTKRRPVSVGEMLKVEFLEPMGITSKALAEAMGVHRNTVSNLINGGVLTAPVAIKLAAALGNTPEFWLNIQHAVDLWDTRNRYQEEAKFVKPLFVSLEQSART
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system that counteracts the effect of the HigB-1 toxin.  Binds to its own promoter and regulates transcription of the higB-1/higA-1 operon.
What are the official names of this protein?
Antitoxin HigA-1.
Protein: DER_RHILW
Sequence: MSFTVAIVGRPNVGKSTLFNRLVGKKLALVDDTPGVTRDRRPGDARLMGLTFTIIDTAGLEEADEESLQGRMRAQTEAAIDEADLSLFVVDAKNGLTPVDTALAEMLRRRGKPVVLVANKSEARGSDSGFYDAYTLGLGEPTPISAEHGEGMLDLRDAIVEAIGKDRAYAKEDVAVTNVDISEAAGEGEDEDEEPLYDDTKPLRVAIVGRPNAGKSTLINRFLGEDRLLTGPEAGITRDSISVEWDWRGRTIKMFDTAGMRRKARVTEKLEKLSVADALRAIRFAETVVIVFDATIPFEKQDLQIVDLVLREGRAAVLAFNKWDMIEDRQAVLADLREKTDRLLPQARGIRAVPISGQTGWGLDKLMQSIIDTDRVWNKRISTAKLNRWLETQQIQHPPPAVSGRRIKLKYMTQVKARPPAFMISCTRSDALPESYTRYLINGLRADFDMPSVPIRIHFRSAENPFEGKKRRT
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: TRUD_VIBVY
Sequence: MTDTLASLAYLAGKPTAQAKIKAKPEHFQVREDLGFEFTGSGEHLMVRIRKTGENTSFVANELAKACGVKSKDVSWAGLKDRHAVTEQWLSVHLPKAETPDFSAFLAQYPSIEILATARHNKKLRPGDLVGNDFVVTLSEVSDVDDVLKRLETVAKLGVPNYFGNQRFGNNGNNLQEAKRWGRDNVRSRNQNQRSLYLSAARSWIFNLIVSARLEQSLFDKVLLGDILFKGDEQLLVSAENHADLQSQYDAGDLVISGALAGDNALPTQDDALALEQVFLDAEPDLMALIRGNRMRHDRRAIALKPANLSWQVDGNNIILTFSLDAGSFATSIIRELVQEIAFEREF
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: RS18_CHRVO
Sequence: MARQLFKRKKFCRFTAEGIKEIDYKSVDLLKDFIAENGKIIPARITGTKARYQRQLTTAIKRARFLAFLPYTDQH
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: MSHR_SAGMI
Sequence: MPMHGAQRKLLGSLNSTPTATSNLGLAANHTGAPCLEVSIPDGLFLSLGLVSLVENVLVVAAIAKNRNLHSSMYCFICCLALSDLLVSGSNMLETAVILLLEAGALATRTSAMQQLHNTIDVLTCSSMLCSLCFLGAIAVDRYISIFYALRYHSIMTLPRAQRAIAAIWVASXLSSTLFITYYDHAAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAHGIIRLHKRQTPAHQGFGLRGAATLTILLGIFFLCWGPFFLHLTLVVFCPQHLTCSCIFKNFKVFLTLIICNTIIDPLIYAFRSQELRRTLKEVLLCSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SLA_CROHD
Sequence: DLECPSGWSSYDRYCYKPFKQEMTWADAERFCSEQAKGRHLLSVETALEASFVDNVLYANKEYLTRYIWIGLRVQNKGQPCSSIYSENLVDPFDCFMVSRDTRLREWFKVDCEQQHSFICKFTRPRR
What is the function of this protein?
Binds to the subunit GPIbalpha (GP1BA) of the platelet GPIb/V/IX receptor system.  It inhibits ristocetin- and vWF-induced platelet aggregation in platelet-rich plasma by inhibiting the binding of vWF to GPIbalpha.
What are the official names of this protein?
Snaclec CHH-B subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: DF292_ARATH
Sequence: MLLETDASRNKPSSYIPLCGSDNSCGGLWCPRKGGKYSCISMTCDIQEDCPKLVRCKDSPGPYCMEGFCTC
What are the official names of this protein?
Defensin-like protein 292.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
Protein: PTPA1_KLULA
Sequence: MDFDYENAKFSMPEKRIFDSQGTLDFQNSVAMVRIQYHLQKYITLCKGQQIPDTIKESFFTNIVVELLKRLSALIDETPPERMHSRYGNLSYRDWQTKFQNQLENWLHELLPEKYNNSIIELSYYISNAFGSKERIDYGTGHELSFLAVIICLDMLKIETIKGPALLYCFNSYYDVIQKLILTYKLEPAGSHGVWGLDDHFHFSYILGATQLLDVNTSLIPKDISNTRLMEQNSSSNLFCKSIRFINVVKSGPFSNHSPLLYNISRSVHTWHKMQQGLIKMYKVEVLNKFPVVQHFWFGTAFFPWTSYGNNHSLPIYQPAENNDDADFLTANNATTKMPPPLSTSTSRFIHRR
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase.  Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A activator 1, Peptidyl-prolyl cis-trans isomerase PTPA-1, PPIase PTPA-1, Rotamase PTPA-1, Phosphotyrosyl phosphatase activator 1.
What is the protein family that this protein belongs to?
Belongs to the PTPA-type PPIase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LPE10_YEAST
Sequence: MRAFPRVLPFRHQRSYNNILLRTVRLFGSSLSSFDFSRQMPKVDPDNTAAMLLQKNLIQRNNMLYGYGSGTIRCTLLDSTGRAKSPLVEIKREDLVSKHGLLPRDLRKIEKSRKNDLVPSLLVRENSILISLLTVKALIKPDMVIIFDSAGSGITLNSEAHKDFINDMKLRLKNQETSELNSDPLPYEFRALETIFISALSNLTSEMKVLLTICKGVLQDLEFSITRDKLRFLLGQNKKLSSFNKKAVLVKDMLDDLLEQDDMLCDMYLTDKKAGKIRVQDDHTEIEMLLETYHNYVDEIVQKSESAISDVKTTEEIINIILDSNRNELMLLGIRYAIGMLSLGGALFLGSIYGMNLESFIEESNYAYLTVTILGLISTVWLYAKGIRHLHKLQRMTLLSKIKTDSVHELLKK
What is the function of this protein?
Mitochondrial inner membrane magnesium transporter required for mitochondrial magnesium homeostasis.  Modulates the conductance of the MRS2 channel.  Involved in the splicing of mRNA group II introns in mitochondria by affecting mitochondrial magnesium concentrations, which are critical for group II intron splicing.
What are the official names of this protein?
Mitochondrial inner membrane magnesium transporter MFM1, MRS2 function modulating factor 1.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.