PharMolix/UniProtQA huggingface dataset:
Protein: PLSX_POLNA
Sequence: MIRIAVDAMGGDIGPDVTLAASLAFLQAHPDAELLLVGQPEVLAAHSLHAQLVAHARCEIVAASEVVTMDDSIEIALRRKKNSSMRVAINQVKEGRAQVAVSGGNTGALMAIARYVLKTLEGIDRPAIASQLPNARGKATTMLDLGANVDCTEEHLLQFAVMGSALVAAIAEIPSPTVGLLNIGEEAIKGGDMIKKAGRLLRAASDSGDINFYGNVEGNDIFKGTTDLVVCDGFVGNVALKSSEGLAHMIGDYIKAEFSRNLLTKMAALVAYPVLSAFKKRFDHRRYNGAALLGLRGLVFKSHGSADVFAFEQALSRAYDAARNNLLERVRERIAHAAPLLVAARAALPAEEALAAPFMSVESTVSTPAH
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: PUR9_MYCUA
Sequence: MSTDHIRRPIRRALISVYDKTGLVDLAQGLTAAGVEIVSTGSTAKTIASKGIPVTRVEELTGFPEVLDGRVKTLHPRVHAGLLADLRNPEHEAALAELGVEAFELVVVNLYPFSQTVESGASVDECVEQIDIGGPSMVRAAAKNHPSVAVVTDPQGYDGVLAAVRSGGFTFAERKKLASLAFQHTAEYDIAVASWMQSTVAPEQPETDFPRWFGRNWRRQAMLRYGENPHQQAALYADPGAWPGLAQAEQLHGKEMSYNNFTDADAAWRAAFDHEQKCVAIIKHANPCGIAISEVSVADAHRKAHACDPLSAYGGVIACNTEVSPEMAEYVSTIFTEVIVAPAYAPAALDQLTKKKNIRVLVASEPQDGGAELRPISGGLLMQQRDQLDAAGDNPANWILATGSPADPATLTDLVFAWRSCRAVKSNAIVIVADGATIGVGMGQVNRVDAARLAVERGGERVNGAVAASDAFFPFPDGLETLTAAGVKAIVHPGGSVRDEEVTAAAAKAGITLYLTGSRHFVH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: Y7B2_ENCCU
Sequence: MRCMEEYLFDRSKLAARPLGKVLAEDYCFDLEREEASGFRVSKGFLWCGECRAMEVDEKTVYLHGSKLFMVSDSLKVYELPSALPSSGLVVRGDDCVYIEKNGRRWTFPDMPEDEVLDGTFLGDRVWIWHAVNTEGRRHLSRSTYLLETEKAVRCEGKMYARDGETILQVQDILVRKDAEICNPTRVWSRGAGDGMVVITTTPDTVWMEYGGYVSSKPCCKEIYGMDGCRLLGLSSCVDVSDLYLTLRLFTDIPVEVEAVEKIEEYLFKLFVFTDRGGRLVEWLVESGMDRQKEMILCRLYRKVDDKGKRVLERWMQGIQSLDALKLIIIYFPEKLERYIKMCIEEKREFEIEEVVEHYQGSDKIEEICLVLLKNSCLHLFSLCMPEYKGRFGDVALVERYNMESQRNMWKTQRIHGDLI
What are the official names of this protein?
Uncharacterized protein ECU07_1120.
Protein: ABA2_PRUAR
Sequence: MASTLFYNSMNLSAAVFSRTHFPIPINKDFPLEFSPCIHTDYHLRSRTRSGQKKCLTEVRATVASPTEVPSAPASTQPKKLRILVAGGGIGGLVFALAAKKKGFDVVVFEKDLSAVRGEGQYRGPIQIQSNALAALEAIDMDVAEEVMRVGCVTGDRINGLVDGVSGTWYVKFDTFTPAVERGLPVTRVISRIALQQILARAVGEEIIINDSNVVNFEDLGDKVNVILENGQRYEGDMLVGADGIWSKVRKNLFGLNEAVYSGYTCYTGIADFVPADINSVGYRVFLGHKQYFVSSDVGGGKMQWYAFHKESPGGVDSPNGKKERLLKIFEGWCDNVIDLLLATEEDAILRRDIYDRTPILTWGKGHVTLLGDSVHAMQPNMGQGGCMAIEDGYQLALELDKAWKKSSETGTPVDVASSLRSYENSRRLRVAIIHGMARMAALMASTYKAYLGVGLGPLSFLTKFRIPHPGRVGGRVFIDKAMPLMLSWVLGGNSSKLEGRSPSCRLSDKASDQLRNWFEDDDALERAIDGEWYLIPCGQDNDASQLICLNRDEKNPCIIGSAPHGDVSGISIAIPKPQVSEMHARISYKDGAFYLTDLRSEHGTWIADIEGKRYRVPPNFPARFRPSDAIEIGSQKVAFRVKVMKSSPGSVEKEGILQAA
What is the function of this protein?
Converts zeaxanthin into antheraxanthin and subsequently violaxanthin.  Involved in the epoxidation of zeaxanthin.
What are the official names of this protein?
Zeaxanthin epoxidase, chloroplastic, PA-ZE.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ALT_BPT6
Sequence: MMELITELFDEDTTLPITNLNPKKKIPQIFSVHVDDAIEQPGFRLCTYTSGGDTNRDLKMGDKMMHIVPFTLTAKGSIAKLKGLGPSPINYINSVFTVAMQTMRQYKIDACMLRILKSKTAGQARQIQVIADRLIRSRSGGRYVLLKELWDYDKKYAYILIHRKNVSLEDIPGVPEISTELFTKVESKVGDVYINKDTGAQVTKNEAIAASIAQENDKRSDQAVIVKVKISRRAIAQSQSLESSRFESELFQKYESTAANFNKPATAPLIPEAEEMKLGINSLASKTKAAKIIAEGTANELHYDYKFFSKSEVNEVSEKIKDVILNAIKNEPTTSIKCLEKYAAAVNQFFEEYKDNWLDKHNKTRKGQPDEVWGEITKNAWNAAKTKFLKRMIYSFSGIGAGPMIDITIARDGSKYTPSQKRGIREYCGSGYTDINNLLLGRYNPERYDVMSEKEIESAINNLDSAFENGDRIPEGITVYRAQSMTAPIYEALVKNKVFYFRNFVSTSLTPIIFGRFGITHAGIGLLEPEARNELTVDKNEEGITINPNEIRAYKENPEYVKVQIGWAIDGAHKVNVVYPGSLGIATEAEVILPRGLMVKVNKITDASNNDGTTSNNTKLIQAEVMTTEELTESVIYDGDCLMETGEVVAMTGDIEIEDRVDFASFVSSNVKQKVESSLGIIASCIDITNMPYKFVQG
What is the function of this protein?
ADP-ribosyltransferase that efficiently ADP-ribosylates one of the two alpha subunits of host RNA polymerase RPOA on an arginine located in the C-terminal region.  ADP-ribosylation of RPOA alpha subunit enhances the transcription of viral early genes.  Also ribosylates RPOA subunits beta, beta' and sigma 70 and performs an autoribosylation reaction.
What are the official names of this protein?
NAD(+)--arginine ADP-ribosyltransferase, Alt protein.
What is the protein family that this protein belongs to?
Belongs to the Tevenvirinae NAD(+)--arginine ADP-ribosyltransferase family.
What are the subcellular locations of this protein?
Virion. Note=About 25-50 copies per virion. This protein is injected into the bacterial cell along with the viral DNA.
Protein: METE_CHRVO
Sequence: MSHATHLLGFPRIGAKRELKTLLERYWKQELDEAALSQGAKELRQKHWLLQKGAGVELSPVGDFSLYDHVLDAQLLVGAAPARFGFDAAALTTGQYFELARGNAVQPAMEMTKWFDTNYHYLVPEWHADTAFSAQPERLLSQLREARALGVAAKPVLLGPLSLLWLGKAKGRPFDRLALLPGLVAAYRELLSSLRAAGAEWAQIDEPILALDLEPSWLDAFAPAYAQLSRHAPKLLLATYFGDVSEHAARLKSLPVAGLHLDLVRAPEQISAFLPDYPADKVLSAGIVDGRNIWRADLSALLDRLAPLAQQLGDRLWLAPSCSLLHSPFDAAAETGLDPELKNWLAFAVQKLNELKTLKRGLEHGRSAIAGELSGSDFAREQRRASPRIHDPAVARRLAALPEGTDRRASPYPIRAERQQAWLKLPPLPTTTIGSFPQTPAIRASRAAFKKGELSAAGYRQAMEKEIELAIRRQEALGLDVLVHGEAERNDMVEYFGEQLAGFAFTAGGWVQSYGSRCVKPPIIFGDVARPKPMTVDWARYAQSLTAKPVKGMLTGPVTILQWSFVRDDLPRREVCRQIALALNDEVLDLEAAGIRVIQIDEPAIREGLPLKRAGRDVYLAWAGEAFRLSSRGVDDATQIHTHMCYSEFGDILPAIAALDADVITIETSRSDMALLADFGRFRYPNAIGPGVYDIHSPRVPSAAEIRALLDKALRVIPAERLWVNPDCGLKTRGWPEVEAALAAMVAVGRELREKLAQAA
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: RL2_FRATW
Sequence: MIEIKKAKPTSPGRRHVVSVKNTELHTGKPFKGLVEVKKSKAGRNNTGRITVRHQGGGHKQHYRIVDFKRNKDDITAKVERIEYDPNRSANIALVLYADGERRYIVAPKGLKKDMSVISGEKVDVAVGNCMPLRNIPLGTVIHNIEMKPKKGAQMIRSAGTFAQLVGKDNAYAIIRLRSGEMRRVLLDCRAVIGVVSNSEHNLKSLGKAGAKRWRGIRPTVRGVAMNPVDHPHGGGEGRTSGGRHPVTPWGIPTKGYKTRRNKRSNKLIVQKRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: GMHA_SHEFN
Sequence: MLERIRDSFTESIQTKIDAAEALPESIEKAAEMMVQCLLGGNKILSCGNGGSAGDAQHFSAELLNRYEIERPPLPAIALSCDTSTITAIANDYSYDEIFSKQIFALGQPGDILLAISTSGNSGNIIKAMEAALSRDMTIVALTGKDGGAMAGLMSAGDVEIRVPSNVTARIQEVHLLVIHCLCDNIDRTLFPQDEQA
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTAD_DESVV
Sequence: MPLPCDTILQAALIVTQDDARTVIEDGAIAIHEGRIAAVGQRDAIVGNWHGATVIDMGASLIMPGLVNAHTHASMTLLRGLADDLPLMDWLTGHIFPVEKGLTGELVELGALLGCAEMLRTGTTAFSDMYLIEDATLRAVDRAGLRCLAGEAIFAFPSPAYADPETAFDLVRAQHDRWKHHARAALAVAPHAVYTSTPAILARCRDLAEELGLPIHLHLAETATETAQCIEQHGARPVPYCDGLGLLTPRTTLAHCVDLTEGEIDLLAERGVTVAHCPESNMKLASGIAPATAMLGRGMTLGLGTDGAASNNSLNMFTEMTSCALLHKVHHMDPTCAPASAVLDMATRGGAHALHMQGIGRIEAGCPADIIALDLRAPNMQPIFNPASHLVYAATGHETRLAMVGGEVLYLDGCYTRFDMDDLLKEVRKARTWAMEQVRAAR
What is the function of this protein?
Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively.  Is also able to deaminate adenosine.
What are the official names of this protein?
5-methylthioadenosine/S-adenosylhomocysteine deaminase, MTA/SAH deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
Protein: TMCAL_BACCZ
Sequence: MQQTKKLTHSDITIAVMSGPFLQRGEPALVSKWYRTKMALACGVDLVVELPYAFSTQKAETFANGAISILNALHVSEICFGSEDGQIENFYNTVSAQKNEEETFNRLVKQFMNAGNSYAKATSEAFLHILSSEKNIDMSQPNNILGFQYIKAILMQNSSMQAQTIKRFASHYHDETFNDQHIASATSIRKQLFSENSSFTEIESFIPKATASLLASYKQNYGTLHNWEQYFSFFKYKLMTMSPKDLQHIYEIEEGLEHRILSKIQTSSSFHSFMEALKTKRYTWTRLQRACTHILTNTTKEEIHCANIEQHAPYIRLLGMSQKGQTYLSKNKKKIELPILTHTKTFDHPTLHIERKANSVYFSIMKEPLRTQLLKRDATHHPIRYDETTAKFL
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMNL3_MOUSE
Sequence: MGNLESTDGGPGEPPSVPLLLPPGKTPMPEPCELEERFALVLSSMNLPPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQSFLDPNVTRKKFRRRVQESTKVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQPPNALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKELHRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSNQVHTLRRLIKEKEEAFQRRCHLEPSARGLESMGGEALARVGPTELTEGIPPSDLDLLAPAPPTEETLPLPPPPAPPLPPPPPPLPDKCPPAPPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQINGTVFSELDDEKILEDLDLDRFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPELANFWQELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITVLKSVPFTARTAKRGSRFFCDAAHHDESNC
What is the function of this protein?
Plays a role in the regulation of cell morphology and cytoskeletal organization.  Required in the control of cell shape and migration.  Required for developmental angiogenesis.  In this process, required for microtubule reorganization and for efficient endothelial cell elongation.  In quiescent endothelial cells, triggers rearrangement of the actin cytoskeleton, but does not alter microtubule alignement.
What are the official names of this protein?
Formin-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the formin homology family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Lipid-anchor. Note=Enriched in lamellipodia.
Protein: ENO_RUBXD
Sequence: MTEIVAVRGREILDSRGNPTLEVEVVTAAGFVGRAAVPSGASTGQNEAVELRDGEGGRYGGKGVLRAVANVEGELAEAVVGMDVTDQRALDLAMIEADGTENKGRLGANAMLGVSLAAARAAAEYAGLPLYRYLGGPGAHVLPVPCANILNGGAHAANNVDFQEFMVVPVGFESYREALRAVAEIYAALKKLLAERGLAGGIGDEGGFAPDLSSNGEALGLLSEAVERSGYSLGEQVCFALDPAASEFYEGGRYELSGEGRSLERGEMVDYYVRLCGEYPIISIEDGLAEDDWEGWEMISARLGGRVQLVGDDLFVTNPKILRKGIERGIANSILVKVNQIGTLTETFETMDLAHKSGYTAMVSHRSGETDDTTIADLAVAVNAGQIKTGAPARGERVAKYNQLLRIEESLGEAAVYPGLGAFNPRMREG
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: YDIY_ECOLI
Sequence: MKLLKTVPAIVMLAGGMFASLNAAADDSVFTVMDDPASAKKPFEGNLNAGYLAQSGNTKSSSLTADTTMTWYGHTTAWSLWGNASNTSSNDERSSEKYAAGGRSRFNLTDYDYLFGQASWLTDRYNGYRERDVLTAGYGRQFLNGPVHSFRFEFGPGVRYDKYTDNASETQPLGYASGAYAWQLTDNAKFTQGVSVFGAEDTTLNSESALNVAINEHFGLKVAYNVTWNSEPPESAPEHTDRRTTLSLGYSM
What are the official names of this protein?
Uncharacterized protein YdiY.
Protein: LEU1_LISW6
Sequence: MKKIQFFDTTLRDGEQTPGVNFDVKEKIQIALQLEKLGIDVIEAGFPISSPGDFECVRAIAKAIKHCSVTGLARCVEGDIDRAEEALKEAVSPQIHIFLATSDVHMEYKLKMSRAEVLASIKHHIHYARQKFDIVQFSPEDATRSDRAFLIEAVQTAIDAGATVINIPDTVGYTNPTEFGQLFQDLRREIKQFDDIIFASHCHDDLGMATANALAAIENGARRVEGTINGIGERAGNTALEEVAVALHIRKDFYQAETNIVLNQFKNSSDLISRLSGMPVPRNKAVIGGNAYAHESGIHQDGVLKNPDTYEIITPALVGVDKNSLPLGKLSGKHAFHTRMEEMGYTLSEQELKDTFKRFKQLADAKKEVTEEDLHALILGQSSESTDNFELKHLQVQYVSGGVQGAIVRIEERDGALIEDAATGSGSIEAIYNTINRLMKQDIELIDYRIQAITAGQDAQAEVHVVIKDNNETEFHGIGIDFDVLTASAKAYLQASGKSKSTTKQVDFEEVK
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: RL21_ACISJ
Sequence: MYAVIKTGGKQYRVAAGEKIKVEQIAAEVGQEIVIDQVLAVGNGAELKVGTPLVSGATVKATVVAHGKHDKVRIFKLRRRKHYQKRQGHRQQFTELQIQAIAA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: SWD1_YEAST
Sequence: MNILLQDPFAVLKEHPEKLTHTIENPLRTECLQFSPCGDYLALGCANGALVIYDMDTFRPICVPGNMLGAHVRPITSIAWSPDGRLLLTSSRDWSIKLWDLSKPSKPLKEIRFDSPIWGCQWLDAKRRLCVATIFEESDAYVIDFSNDPVASLLSKSDEKQLSSTPDHGYVLVCTVHTKHPNIIIVGTSKGWLDFYKFHSLYQTECIHSLKITSSNIKHLIVSQNGERLAINCSDRTIRQYEISIDDENSAVELTLEHKYQDVINKLQWNCILFSNNTAEYLVASTHGSSAHELYIWETTSGTLVRVLEGAEEELIDINWDFYSMSIVSNGFESGNVYVWSVVIPPKWSALAPDFEEVEENVDYLEKEDEFDEVDEAEQQQGLEQEEEIAIDLRTREQYDVRGNNLLVERFTIPTDYTRIIKMQSS
What is the function of this protein?
The COMPASS (Set1C) complex specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.
What are the official names of this protein?
COMPASS component SWD1, Complex proteins associated with SET1 protein SWD1, Set1C component SWD1.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: RS23_SACU7
Sequence: MGKGKPRGLNSARKLRVHRRNNRWAENNYKKRLLGTAFKSSPFGGSSHAKGIVLEKLGIESKQPNSAIRKCVRVQLIKNGKKVTAFVPNDGCLNFVDENDEVLLAGFGRKGKAKGDIPGVRFKVVKVSGVSLLALWKEKKEKPRS
What are the official names of this protein?
40S ribosomal protein S23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: SIR5_TRYB2
Sequence: MRRPNGMIAILTGAGISAESGISTFRDQNGLWENHRVEDVCTPAAFLKQPTVVQRFYNERRRALLSPEVKPNASHQALARLQREYKDGQVVIITQNIDDLHERAGSRQVLHMHGELLKVRCTATGRVFESREDVIHGESKCECCGVVETLRPHIVWFNEMPLYMDVIDEVVQNAGLFVAVGTSGNVYPAAGLVMIAKAHGAETLELNLEPSGNCRDFDRSVYGPASVIVPAWADEVLHGKGPAA
What is the function of this protein?
NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins.  Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
What are the official names of this protein?
NAD-dependent protein deacylase SIR2rp3, Regulatory protein SIR2 homolog 5, SIR2-related protein 3.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class III subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NFRA_STAHJ
Sequence: MSDYVYDLMKKHHSVRQFKDKALSDETVQKLVEAGQSASTSSYLQTYSIIGVDDPEIKKQLKEVSGQPYVVDNGYLFVFVLDYYRHNLINENVDFDMQTSFESAEGLLVGAIDVALVSENVALAAEDMGYGIVYLGSLRNDVARVKEILDLPEYAFPLFGMAVGEPADDENGAPKPRLPFEHVFHKNVYNSNAKEQREAIQKYDEEISEYYKERTNGKRQETWSQQVAGFLSGKTRLDMLEELNKSGLMKK
What is the function of this protein?
Reduces FMN, organic nitro compounds and disulfide DTNB.  Involved in maintenance of the cellular redox state and the disulfide stress response (By similarity).
What are the official names of this protein?
NADPH-dependent oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the flavin oxidoreductase frp family.
Protein: RL16_STRP3
Sequence: MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSHWITNRQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKVMFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RL20_BACC7
Sequence: MPRVKGGTVTRQRRKKVIKLAKGYYGSKNTLFKVANQQVMKSLMYAFRDRRQKKRDFRKLWITRINAAARMNGLSYSRLMHGLKNAGIEVNRKMLADLAVHDEKAFAELATVAKNNIN
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: TRM56_METMJ
Sequence: MPEVAVLRIGHRPERDQRVTTHVGLAARALGARGMYLAADDPGVALSITDVASRWGGDFFIENDVKWRRCIQDWKAAGGKVAHLTMYGLRMTDVIDDIRTEERVLVVVGAEKVPGDIYGLADYNVSVTTQPHSEISSLALFLDHLFEGKELNREYPDAKIRIEPTKVGKKTVER
What is the function of this protein?
Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.
What are the official names of this protein?
tRNA (cytidine(56)-2'-O)-methyltransferase, tRNA ribose 2'-O-methyltransferase aTrm56.
What is the protein family that this protein belongs to?
Belongs to the aTrm56 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NF45_NAEFO
Sequence: SHDVNINIQFGFENPQQVVD
What are the official names of this protein?
Unknown protein NF045 from 2D-PAGE.
Protein: ATG42_YEAST
Sequence: MKYLNLVFVLQLLISIKYASFGRAFSLFEDDTTFANLDKQLKLPQNTQQTLKLDRLNHDDPLFTTFISSVDTDYSLRLRTVDPSKLGIDTVKQWSGYMDYKDSKHFFYWFFESRNDPANDPIILWLNGGPGCSSFTGLLFELGPSSIGADMKPIHNPYSWNNNASMIFLEQPLGVGFSYGDEKVSSTKLAGKDAYIFLELFFEAFPHLRSNDFHIAGESYAGHYIPQIAHEIVVKNPERTFNLTSVMIGNGITDPLIQADYYEPMACGKGGYHPVLSSEECEKMSKAAGRCRRLNKLCYASKSSLPCIVATAYCDSALLEPYINTGLNVYDIRGPCEDNSTDGMCYTGLRYVDQYMNFPEVQETLGSDVHNYSGCDNDVFTGFLFTGDGSKPFQQYIAELLNHNIPVLIYAGDKDYICNWLGNHAWSNELEWINKRRYQRRMLRPWVSKETGEELGQVKNYGPFTFLRIYDAGHMVPYDQPEASLEMVNSWISGNRAFSDLSTLENAS
What is the function of this protein?
Vacuolar serine-type carboxypeptidase involved in vacuolar zymogen activation, breakdown of the autophagic body, and autophagosome-dependent protein synthesis (PubMed:29514932).  Plays a key role in phytochelatin (PC) synthesis from glutathione (GSH) by cleaving the Gly from GSH and form the PC-peptides of the structure (gamma-Glu-Cys)2-Gly (PubMed:17408619).  Also involved in resistance to xenobiotics via the degradation of glutathione-S-conjugates (PubMed:19897216).
What are the official names of this protein?
Vacuolar serine-type carboxypeptidase ATG42, Carboxypeptidase C, CPC.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Vacuole lumen. Note=The vacuolar sorting receptor VPS10 is required for the delivery of ATG42 to the vacuole lumen.
Protein: Y696_IDILO
Sequence: MLRWVLIFLAVAVVAAILGFGGIAGTAAGIAKIIFYIFIILFAISLVVRLLQGNKRL
What are the official names of this protein?
UPF0391 membrane protein IL0696.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TUSD_YERPY
Sequence: MSALKYCLLVTGPAYGTQQASSAYQFAQAVVGAGHHLVSIFFYREGVLNANQLTAPASDEFDLVRAWQQLAAEQAVTLNVCVAAALRRGITDQHEAEQLNLAAANLQPGFTLSGLGALAEATLTCDRMVQF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Accepts sulfur from TusA and transfers it in turn to TusE.
What are the official names of this protein?
Sulfurtransferase TusD, tRNA 2-thiouridine synthesizing protein D.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KYNB_BACMK
Sequence: MKTSQWIDISQPLNNDIATWPGDTPFSYEVSWSKENSGSVNVGKLTMSIHTGTHIDAPFHFDNDGKKVLDLDIQVYVGPARIIDVSNLESIGKKELENFHLEGVERLLLRTSSHGKANEFPDVIPHLRADIAAFLSEKGIRLIGVDVPSVDPLDDKELAAHHQLFKHGIHILENVVLDHVVDGDYELIALPLALTDADGSPVRAVIRPI
What is the function of this protein?
Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
What are the official names of this protein?
Kynurenine formamidase, KFA, KFase, Arylformamidase, N-formylkynurenine formamidase, FKF.
What is the protein family that this protein belongs to?
Belongs to the Cyclase 1 superfamily. KynB family.
Protein: SYT_DICNV
Sequence: MPTITLPDGSKKSFNAAITGQEIAESIGSSLAKAAIAVRIGEKLQDLSDTIACDADVTIITDKDEAGLEIIRHSCAHLLGHALKQLWPQAKMVIGPVIENGFYYDIEADHRFTPEDLAVLEERMQKLAATGYSVKKEWTPVARAREIFHERQEDFKIRLIDDFDADVKEVGLYYHQEYVDMCRGPHVPDMGKIKAFKLTKLSGSYWRGDAQAEALQRIYGVAFRSKKELDDYLTQQAEAEKRDHRKIGKALDLFHLQEEAPGMVFWHAKGWTIYREIENYMRTKLRKYGYQEVQGPQILDRSLWEKSGHWDKFGGNMFTCCIDNHDFAVKPMNCPGHVQIFNQGLKSYRELPIRYAEFGICHRNEPSGTLHGIMRVRRFVQDDGHIFCARNQVRVEIERTCRMVYEVYDDFGFKNVELALSTRPEKRVGSDEIWDEAERGLQEALEAQNLAFRLQPGEGAFYGPKIEFTLKDSLGRRWQCGTVQLDFSMPARLGAEYIDEHGEKQTPVMIHRAILGSLERFIGILIEQYAGNMPVWLSPVQAMIMPITDTHADYVQNVMQKFIAAGIRAEIDLRNEKISYKIREHTLQRVPFLLVAGDREKQSNTLSVRTRDGKELGVMEIATIIEHIRHLIETKSQEIE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_CUPNH
Sequence: MNALVNLLDLDADALTAYCGELGEKPFRARQLQRWIHHYGASRFDAMSDLAKSLREKLATRAEIRAPAAITDHLSADGTRKWLLDVGQGNAVETVYIPEETRGTLCVSSQAGCAVNCRFCSTGKQGFSRNLSTGEIIGQLWMAEFAMREQLGRGPKDDRVISNVVMMGMGEPLLNYDAVVPAMRLMLDDNAYGLSRRRVTLSTSGVVPMMDRLSKDLPVALAVSLHASNDALRDVLVPLNKKYPLAELMAACRRYLEFAPRDFITFEYCMLDGVNDGVEHARELLKLVADVPCKFNLIPFNPFPESGLKRSNNDQIRRFAQVLMDAGIVTTIRKTRGDDIDAACGQLAGEVKDRTRLVERGKFGKITPLVPVAASGQPREVRPA
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.