PharMolix/UniProtQA huggingface dataset:
Protein: AP5M1_HUMAN
Sequence: MAQRAVWLISHEPGTPLCGTVRFSRRYPTVEKRARVFNGASYVPVPEDGPFLKALLFELRLLDDDKDFVESRDSCSRINKTSIYGLLIGGEELWPVVAFLKNDMIYACVPLVEQTLSPRPPLISVSGVSQGFEFLFGIQDFLYSGQKNDSELNTKLSQLPDLLLQACPFGTLLDANLQNSLDNTNFASVTQPQKQPAWKTGTYKGKPQVSISITEKVKSMQYDKQGIADTWQVVGTVTCKCDLEGIMPNVTISLSLPTNGSPLQDILVHPCVTSLDSAILTSSSIDAMDDSAFSGPYKFPFTPPLESFNLCFYTSQVPVPPILGFYQMKEEEVQLRITINLKLHESVKNNFEFCEAHIPFYNRGPITHLEYKTSFGQLEVFREKSLLIWIIGQKFPKSMEISLSGTVTFGAKSHEKQPFDPICTGETAYLKLHFRILDYTLTGCYADQHSVQVFASGKPKISAHRKLISSDYYIWNSKAPAPVTYGSLLL
What is the function of this protein?
As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport.  According to PubMed:18395520, it may play a role in cell death.
What are the official names of this protein?
AP-5 complex subunit mu-1, Adaptor-related protein complex 5 subunit mu-1, Mu5, Mu-2-related death-inducing protein, MuD, Putative HIV-1 infection-related protein.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes medium subunit family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=May cycle on and off membranes.
Protein: Y1393_RHIME
Sequence: MIYVDADACPVKPEILKVAERHGLEVTFVANSGLRPSRDPMVRNVIVSAGFDAADDWIAERAKDGDIVVTADVPLAVRCVGAGALVTGPTGRVFDETNIGMASAMRDLSAHLRETGESKGYNAALTSRDRSAFLETLDRLCRRVKR
What are the official names of this protein?
UPF0178 protein R01393.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: TOP3_ALKCK
Sequence: MKKKAVLAEKPSVARDIARVLGCNQKGNGYLEGNGYIITWALGHLVTHADPEHYGKQYKTWKLEELPMLPKRLELVVIKQTAKQFHAVKHVLNRQDVGEVVIATDAGREGELVARWILEKAHVKKPVKRLWISSVTDKAIKDGFKQLKDGKRYETLYAAAAARAEADWYVGINGTRALTTKHNAQLSCGRVQTPTLAILADREEAIRKFVPKPYHTISVETKDGVTFRWADRRSKEERIFDDKRAKTLQEKLQQSAIVIDSVNAKTKRTPPPPLYDLTELQREANKRFGYSAKETLAALQRLYEQHKAVTYPRTDSRYLSSDLVETLKERLHAVDVQPFRKMVANAKKQGLANAKRQMVNDAKVSDHHALIPTEQPQSASAMSDKEAKLYHLIVRRFLANFFPPSESELTSVEATANGELLRAKGERLVSAGWRGQETGEEDEALARLLPAMSKGDKKAVKWVGMTQGKTSPPPRFNEGTLLAAMEKPAQHMEAKDETIKKTLAQAGGIGTVATRADIIEKLFSSFYIEKKGKDLYITSKGKQLLELVPAELKSPALTAEWEQRLEKIVQGKEQKQMFIAEMKEYAKAVVAQVKADTATFRHDNKTGEKCPECGKFLLEVNGKKGKMRVCQDRECGYRKNIAMTTNARCPKCKKKLELRGEGEGQVFACVCGHREKKAQFEQRRKQNKHKNVSKREVQSYMKKQNKQDQFANSALADQLAKLGLKGDDS
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 3, DNA topoisomerase III.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: MTNN_ECOHS
Sequence: MKIGIIGAMEEEVTLLRDKIEKRQTISLGGCEIYTGQLNGTEVALLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGLAPTLKVGDIVVSDEARYHDADVTAFGYEYGQLPGCPAGFKADDKLIAAAEACIAELNLNAVRGLIVSGDAFINGSVGLAKIRHNFPQAIAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQSSLMVESLVQKLAHG
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.  Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: S6A13_HUMAN
Sequence: MDSRVSGTTSNGETKPVYPVMEKKEEDGTLERGHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLVFLFTCGIPVFLLETALGQYTSQGGVTAWRKICPIFEGIGYASQMIVILLNVYYIIVLAWALFYLFSSFTIDLPWGGCYHEWNTEHCMEFQKTNGSLNGTSENATSPVIEFWERRVLKISDGIQHLGALRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGVTLPGAAQGIQFYLYPNLTRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCIALCFLNSGTSFVAGFAIFSILGFMSQEQGVPISEVAESGPGLAFIAYPRAVVMLPFSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPHVFRKKNRREVLILGVSVVSFLVGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGAKRFYDNIEDMIGYRPWPLIKYCWLFLTPAVCTATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALSSMVCIPAWSLYRLGTLKGPFRERIRQLMCPAEDLPQRNPAGPSAPATPRTSLLRLTELESHC
What is the function of this protein?
Mediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA) (PubMed:17502375, PubMed:22932902).  Mediates transport of beta-alanine (PubMed:17502375).  Can also mediate transport of taurine and hypotaurine (By similarity).
What are the official names of this protein?
Sodium- and chloride-dependent GABA transporter 2, GAT-2, Solute carrier family 6 member 13.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A13 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.
Protein: MASZ_SHIFL
Sequence: MSQTITQGRLRIDANFKRFVDGEVLPGVELDAAAFWHNVDEIVHDLAPENRQLLAERDRIQAALDEWHRSNPGPVKDKAAYKSFLRELGYLVPQPERVTVETTGIDSEITSQAGPQLVVPAMNARYALNAANARWGSLYDALYGSDIIPQEGAMVSGYDPQRGEQVIAWVRRFLDESLPLENGSYQDVVAFKVVDKQLRIQLKNGKETTLRTPAQFVGYRGDAAAPTCILLKNNGLHIELQIDANGRIGKDDPAHINDVIVEAAISTILDCEDSVAAVDAEDKILLYRNLLGLMQGTLQEKMEKNGRQIVRKLNDDRQYTAADGSEISLHGRSLLFIRNVGHLMTIPVIWDSEGNEIPEGILDGVMTGAIALYDLKVQKNSRTGSVYIVKPKMHGPQEVAFANKLFTRIETMLGMAPNTLKMGIMDEERRTSLNLRSCIAQARNRVAFINTGFLDRTGDEMHSVMEAGPMLRKNQMKSTPWIKAYERNNVLSGLFCGLRGKAQIGKGMWAMPDLMADMYSQKGDQLRAGANTAWVPSPTAATLHALHYHHTNVQSVQANIAQTEFSAEFEPLLDDLLTIPVAENANWSAQEIQQELDNNVQGILGYVVRWVEQGIGCSKVPDIHNVALMEDRATLRISSQHIANWLRHGILTKEQVQASLENMAKVVDQQNAGDPAYRPMAGNFANSCAFKAASDLIFLGVKQPNGYTEPLLHAWRLREKESH
What is the function of this protein?
Involved in the glycolate utilization.  Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
What are the official names of this protein?
Malate synthase G.
What is the protein family that this protein belongs to?
Belongs to the malate synthase family. GlcB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_SALTI
Sequence: MTFTASSSSCAITESPVVVALDYHERDKALAFVDKIDPRDCRLKVGKEMFTLFGPQLVRDLQQRGFDVFLDLKFHDIPNTTARAVAAAADLGVWMVNVHASGGARMMAAARDALAPFSKDAPLLIAVTVLTSMGTSDLHDLGVTLSPAEHAERLARLTQQCGLDGVVCSAQEAVRFKQAFGAAFKLVTPGIRPAGSEAGDQRRIMTPEQALSAGVDYMVIGRPVTQSVDPAQTLKDINASLKREA
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: IF2_CELJU
Sequence: MAEVTVNELATSIGAPVERLLKQMQEAGLQHKTASAKVSDEEKQRLLAYLKGSHGEAAVEPRKITLQRKTTTTIKTGTGNAKKTVNVEVRKKRTYVKREDDVVDNTQAAQSQEQDDELASTVVEEVQQAEPSVVPVVDVAPEPEPEPVVEEVDVAAEEAEPVEAAVDTSAPTRFSFTDGIEEKRRAAIERRQAEEAARQAELKAIEEAKRAAEEAKRTQPRAEKPADKSAAAGKGAKPDNRQPAKGKQAPVAVPVEREDAKHGHGHKKHHHGRNDDDFDDDSADRGNKRGAGKAVKKAAAPKKSSKIDLLDFVGDDSEDSDVLARRSHIRAHHKKNNKHAFKKPTTQIVHEIDIPETIAVSELAQRLTIKVGELIKRLMKMGVMASMNEQIDQDTAVLIVEELGHKANLVSENDIEHALEKSLETAGELTTRAPVVTVMGHVDHGKTSLLDYIREAKVAAGEAGGITQHIGAYRVTTSRGEITFLDTPGHAAFTAMRARGAKATDVVILVVAADDGVMPQTEEAIMHARAAEVPIVVAINKCDKPSADPDRVTNELVAKGVIPEAYGGDTQFVQVSAHTGQGIDELLEAISLQAEVLELTAVTNAAAKGVVIEARVDKGRGTVATVLVQQGTLKQGDLILAGQSYGRVRAMVNERGEQVKEAGPSTPVEILGLDMPPSAGDDFVVLDDERKAREVAAFRAEKERKEKLARFQAAKLENMFSNMEAGQKKTLTVVIKADVRGSLEAIQASLADIGNDEVQVNVISSGIGGITENDVNLAVTSGAIIVGFNVRADGATRRLAETEGVDIRYYSIIYQLLDEVKAALSGMLDPERVETIVGIANVREVFNSPKFGQVAGCMVVEGTVYRNKPIRVLRDNVVIFTGELESLRRFKDDVNEVRNGFECGIGVKNYDVKVGDQIEVYEVKEVARQL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CECB_ANTPE
Sequence: KWKIFKKIEKVGRNIRNGIIKAGPAVAVLGEAKAL
What is the function of this protein?
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Cecropin-B.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DNAJ_AGRFC
Sequence: MAKADFYETLGVSKTADEKELKSAFRKLAMKFHPDKNPDDADSERKFKEINEAYETLKDPQKRAAYDRFGHAAFENGGMGGGGMGGGGFANGGFSDIFEDIFGEMMGGGRARRSSGGRERGADLRYNMEITLEEAFAGKTAQIRVPTSITCDVCSGSGAKPGTQPKTCATCQGSGRVRAAQGFFSVERTCPTCHGRGQTISDPCGKCHGQGRVTEERSLSVNIPSGIEDGTRIRLQGEGEAGMRGGPAGDLYIFLSVRPHEFFQRDGADLYCTVPISMTTAALGGTFDVTTLDGTKSRVTVPEGTQPGKQFRLKGKGMPVLRSAQTGDLYIQIQIETPQKLSKRQRELLQEFEQLSSKENNPESTGFFARMKEFFDG
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHS1_EXODE
Sequence: MVPFWTVVTDQHIKYTSHNKAGFIIDEEQHHWPPSSGSSLGRAPSIPLSSSNPRSPIRPSTPSRVSTDWTRPPAPSVAYEARDINGSPRLEPHHHNMEEVLEGLCHRAALFGQGGCGRNDNPNARAGVGKRCLCRSLLDNAGQRPKGKLEIGTFVHDCLDLYGRWCHYQSEVESLWPSAGRKTRYARPSRSTNDQEGGYVDQWRADSRMYIPTILHSFLPRRDEREFTHMRYTAVTCDPDDFVVKGYKLRQNIGPTMRETELFICVTMYNEDEIEFTRTMHGIMRNIAHFCSRTRSRTWGKDGWQKIVVCVIADGRQKVHPRTLNALAAMGVYQDGIAKNVVNQKEVTAHVYEYTTQVSLDETLKFKGAEKGIVPCQMIFCLKEKNKKKLNSHRWFFNAFGRALIPNVCILLDVGTKPDSKALYHLWKAFDQNSNVAGAAGEIKADKGKGWLGLLNPLVASQNFEYKISNILDKPLESVFGYITVLPGALSAYRYHALQNDPSGHGPLSQYFKGETLHGRDADVFTANMYLAEDRILCWELVAKRDEQWVLKFVKSAYGETDVPDTVPEFISQRRRWLNGAFFAAVYALVHFKQIWRTDHSLTRKILLHIEFIYQFISLLFTFFSLANFYLTFYFVAGSLADPTIDPFGHNIGKYIFVILRYVCVLLICLQFILSLGNRPQGEEIVSEYHGDVFHHHGIHDLCLRVYCHQATYDARSRKDRPQQSYKLGNNIFTNLIVSSVSTIGLFFLMSFLYLDPWHMFTSSAQYFALLPSYICTLQVYAFCNTHDVTWGTKGDNVMHTDLGAAKAIGSGNTVEVEMPSEQLDIDSAYDVALRNLRDRVEVPKPPVSENQLQEDYYKSVRTYVVASYMVCNAILAMAVSEAYPVGSHIGSNFYLTFILWSVAALALFRAIGSSAFGVINIVSAIAEGRIQAKFERIFGGGDERGRHRAGLGSGFSESGKTGITSGSGMSGMSLSDVTSKISEKLAG
What is the function of this protein?
Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.
What are the official names of this protein?
Chitin synthase 1, Chitin-UDP acetyl-glucosaminyl transferase 1, Class-II chitin synthase 1.
What is the protein family that this protein belongs to?
Belongs to the chitin synthase family. Class II subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PPE1_MOUSE
Sequence: MGCGTSSKKGNKSKKVIKAALVIQNWYRRYRARLRVRQHYALAIFQSIEYSDEQGQMQLSSFFSFMLENYTKTNNEDSALVTRIFDNTRRESQIKDRDDFLGLIEVPDSYDGPRLQFPLTFTDIHILLQAFKQQQILHAHYVLEVLFEARKVLKQMPNFSHVKTFPAKEITICGDLHGKLDDLMLIFYKNGLPSENNPYVFNGDFVDRGNNSMEILMILLVCFLVYPSDLHLNRGNHEDFMMNLRYGFTKEILQKYKLHGRKILQVLEEVYTWLPIGTIIDNEILVIHGGISESTDLNTLHQLQRNKMKSVLMPPVLGNQETGEKRNKSASNYVEPRKVEPDKTPSEDLTKQEWEQIVDILWSDPRGKKGCYPNTSRGGGCYFGPDVTSKVLSKNQLKMLIRSHECKPDGYEVSHDGKVITVFSASNYYEEGSNRGAYIRLSYGTMPQFFQYQVTSTSCLNPLHQRMNAMESSAFKILKEKMISRKTDLINAFELRDHSRSGRISLAEWAFSMENILGLNLPWRSLSSHLVTIDSSGSVDYMSSFDDIRIEKPTKDMKSNLTETMYRYRSDLKIIFNIIDSDQSGLISMDEFRTMWKLFNAHYKAHIDDSQIDELASIVDFNKDGNIDFNEFLKAFYVVHKYDKPGTSLA
What is the function of this protein?
May have a role in the recovery or adaptation response of photoreceptors.  May have a role in diverse sensory neurons and in development.
What are the official names of this protein?
Serine/threonine-protein phosphatase with EF-hands 1, PPEF-1, DRES10, Protein phosphatase with EF calcium-binding domain, PPEF.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family.
Protein: GATC_LEPBL
Sequence: MNLNEDSLRKIAELSRLNIRPKEKEATLRDFNKILEYVDQVKGLDVSSIRDDEIYFRHENSIRPDLVGQHLSREEIEKFAPSFQNGYFVVPKVIET
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: GLYA_FRATT
Sequence: MFSFEKNSLKNTDKEIFDAIELEVKRQHEHVELIASENYASPAVMEAQGSQLTNKYAEGYHGKRYYGGCEFVDIAEKLAIERAQQLFGVDYANVQPHSGSQANAAVYNAVLKPGDTVLGMDLGAGGHLTHGSKVNFSGKIYNSIQYGLDENGDIDYKQVAQLAKEHKPKMIIAGFSAFSGIINWQKFREIADSVDAVLMADIAHVAGLVAAGVYPNPFPYVYVATTTTHKTLRGPRGGLILCNNNPELAKKFQSAIFPGIQGGPLMHVIAAKAVAFKEALEPSFVDYQKQVLKNAKAMEKVLKQRGINIISGGTSNHLLLLDITNTGFSGKEAEAALGRANITVNKNSIPNDPRSPFVTSGLRIGSPAITTRGFKEKECELVANLLADVVFNCGDEKVENETAAKVLDLCDKFPVYK
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJQB_BACSU
Sequence: MEDMYDSFAALSASESEYRIIYEEKNGSELIVLGPHGGRIEPGVSELVRAFSDRCSIYLFEGLKQRNNRSLHLTSIRFDEPLALEKVNDHHYALAFHGYYDPKIPHTLVGGADRKKAKLICERLNEAGFSAELTNEKDRLAGVHPNNIVNRTKREMGLQLEVSTAQRNALFRNFGCRDKSYIQNDLFDRYVEAVKLGFYT
What are the official names of this protein?
UPF0714 protein YjqB.
What is the protein family that this protein belongs to?
Belongs to the UPF0714 family.
Protein: CLS1_STAAC
Sequence: MRFTFSNDLGTLFTIILAIGFIINLVLAFIIIFLERNRRTASSTWAWLFVLFVLPLIGFILYLFFGRTVSARKLNKNNGNVLTDFDGLLKQQIESFDKGNYGTDNKQVQKHHDLVRMLLMDQDGFLTENNKVDHFIDGNDLYDQVLKDIKNAKEYIHLEYYTFALDGLGKRILHALEEKLKQGLEVKILYDDVGSKNVKMANFDHFKSLGGEVEAFFASKLPLLNFRMNNRNHRKIIVIDGQLGYVGGFNIGDEYLGLGKLGYWRDTHLRIQGDAVDALQLRFILDWNSQAHRPQFEYDVKYFPKKNGPLGNSPIQIAASGPASDWHQIEYGYTKMIMSAKKSVYLQSPYFIPDNSYINAIKIAAKSGVDVHLMIPCKPDHPLVYWATFSNASDLLSSGVKIYTYENGFIHSKMCLIDDEIVSVGTANMDFRSFELNFEVNAFVYDENLAKDLRVAYEHDITKSKQLTKESYANRPLSVKFKESLAKLVSPIL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase 1, CL synthase 1.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNME_PELTS
Sequence: MLDDTIAAISTPIGEGGIGIVRISGPDAVKVAKKFFLTKRKDWDQAGSHRLIYGHVFDREGNIVDEVLLSFMRAPRTYTREDVVEINCHGGIVPLRKVLELALANGARLAEPGEFSKRAFLNGRLDLAQAESVIDIIRSKTEAGLRVAVSQLRGDLSRKVEDLQGRLLGLLAQVEANIDFPEDDLEEATVEDILRSGEDLIEEIKEIVRRAEAGKIYREGISTVIIGRPNVGKSSLLNALLRENRAIVTDIPGTTRDIIEEYINIRGIPLKIIDTAGLRETGDAVERIGVEKAREAVEQADLVLLVLDAARGLTEEDYAIIEKVGGKKVIFIVNKADVREKKISSEGAARIAGGRPVLWISALEGTGLDKLEEKIVEMVMGGQVYPKDELIISNTRHRMAMERAADHLAEAVSGIRQNVPVDVVAIDLRAAWESLGEITGTTVTEDLIDRIFADFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_CLOAB
Sequence: MKLHELKPAAGSRKAPKRVGRGTGSGLGRNAGKGEKGQNARSGGGVRPGFEGGQMPLYRRLPKRGFTNIFAKTITAVNVDRLNIFEDGTEVTIDALIEKGIIKKVNDGVKILGNGELKKKLVVKVNKYSKSAAEKIEAAGGKAEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RS18_SHEDO
Sequence: MARYFRRRKFCRFTSEGVAEIDYKDIVTLKNYITESGKIVPSRITGTSAKYQRQLARAIKRARYLSLLPYTDLHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: UXT3_ARATH
Sequence: MSEGQKFQLGTIGALSLSVVSSVSIVICNKALISTLGFTFATTLTSWHLLVTFCSLHVALWMKMFEHKPFDPRAVMGFGILNGISIGLLNLSLGFNSVGFYQMTKLAIIPCTVLLETLFFRKKFSRKIQFSLTILLLGVGIATVTDLQLNMLGSVLSLLAVVTTCVAQIMTNTIQKKFKVSSTQLLYQSCPYQAITLFVTGPFLDGLLTNQNVFAFKYTSQVVFFIVLSCLISVSVNFSTFLVIGKTSPVTYQVLGHLKTCLVLAFGYVLLRDPFDWRNILGILVAVIGMVVYSYYCSIETQQKASETSTQLPQMKESEKDPLIAAENGSGVLSDGGGGVQQKTVAPVWNSNKDFQA
What is the function of this protein?
Nucleotide-sugar transporter that transports UDP-xylose and UMP in a strict counter-exchange mode.
What are the official names of this protein?
UDP-xylose transporter 3.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. TPT (TC 2.A.7.9) subfamily.
Protein: EFP_STRP1
Sequence: MIEASKLKAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDVRTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDDTAYFMNTDTYDQYEIPVANVEQELLYILENSDVKIQFYGSEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATLETGLVVNVPDFIEAGQKLIINTAEGTYVSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity).
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMI_SHESH
Sequence: MTTRKRPLALLILDGWGYRENTQKNAVYHANTPVLDRLNAQYPNSLISGSGLDVGLPDGQMGNSEVGHINIGSGRIVYQELTRIGKAIEDGEFDKNQALVESIDKAIANQGAVHIMGLLSPGGVHSHESHIEAMCRLAVARGAKQVYLHAFLDGRDTPPRSAKGSLAHFDDLFTTLGTGRVASVIGRYYAMDRDNRWDRVSQAYELITEGKSLHQYSNAVEALEAAYARDENDEFVGSSAILDAQGDSAQLADGDALIFMNFRADRARQITRSFVDADFDGFERNVTPKAHFVMLTEYAADIKAAIAYPSTNLVNTLGEALQDSDKTQLRISETEKYAHVTFFFNGGKEEPFKGEDRILIQSPKVATYDLQPEMSSAELTDKLVEAIESTKYDVIICNYPNGDMVGHTGSFDAAVKACEAVDTCIGRVVDALAKVDGECLITADHGNAEQMTDEQTGQAHTAHTSELVPLIYVGRNGSIENDGRLSDLAPTMLTLMGEEVPSEMTGRSIIKLDE
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: ACLK_ASPOR
Sequence: MASSLELPKFEPDRDRLVWYLAYGSNLSSQTFREDRQITPQAAVTITVPGWRLTLSSAGFPYREPSFASIVNVGSAGPTDEKHDGPCELPLHGTAYLITWSQWIKIVASEGGGIVYKEALLRGQPIQPQDQQRWGAELSVLTLVSTMERWPEPRPSQRYMGLILDGARAADFPASYIAQIRHKHPCYQPPSTTWERIGATLFLGFWTPVLTLLSLLTHAAARAGPGDDGHVPEGVRALVRFAMFTMWWVHDLIWSRIWGRGDGLFPGAMQLNG
What is the function of this protein?
Gamma-glutamyl cyclotransferase; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411).  The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411).  One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411).  After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411).  In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411).  Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411).
What are the official names of this protein?
Gamma-glutamyl cyclotransferase aclK, GGCT aclK, Aspirochlorine biosynthesis protein K.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein: MINC_BORPE
Sequence: MNTESLALDFKSATLYAIRVVLHDADTTRLRAALDKRMADAGSFFENEPVVIDATRVDAPVDWPALLQALADHNLPPIGVVAEGANLQGARDAGLVPVELSTSVARAPQVIDTAPPNDVATPVPSVPEATAEATAKAGPQDDEADGEQADEAPAHNPESVPTRAARETTEANRPTATPPQSSSALVITKPLRSGQRVYARHTDLIVIGMVSQGAEVIADGNVHVYGPLRGKAMAGARGDTSARIFTTQLDAELLAVAGVYRVVEDKLDRALHNQPALVRLDGDTLRIEALKG
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.