PharMolix/UniProtQA huggingface dataset:
Protein: ATG9_CANGA
Sequence: MEQSGHEPGKNTFLSRVFGLQSDDVSTSIHTQELSTIPLDEDESNHGALVESEDDEDHNDGVRLLESDPGTSTQDSLESDTSEEDERINGINSDSQVIDTSRPLLSKKETMELHPFGSQNGRIMESSIKLGQPSSDEEDLINVNESLQPDLENRINPIYHEDKLDKALGNSSKNIRTSTFLDRVLKPNDVKKNSTKKRQNSHNYNPTSTYTNSSSNTFLNTVKGEKSSKKYKLKRPNILNALSVVNNMPERRLNTLSPKERALWKWANVDNLDLFLQDAYNYYLGNGFHCIILQKVLNILTLLFVVFVSSFMGYCVDYSKLPTSTRFSEIKIDHCYSQNITGFTKFLLFLFYGFVILKVIQLYFDINNIREMKLFYHYLLNISDDELQTIPWQNIIQQLMYLKDQNALTANVVAVKAKNKLNAHGIANRIMRKENYLIALYNNDILDLRFPIPFFGSQPLTKTLEWNINLCVMGYVFNEAGFIKQGFLKATQKEYFANELRKRFMLAGFLNIILSPFLVSYFVLLYFFRYFNEYKTSPENIGARQYTPMAEWKFREYNELYHIFRKRIGLSNPLASKYVDQFPKEKTNILLKFVSFISGSFVAILAILALWDPENFLNFEVTHDKTVLFYITVLGAIWSISQGSVSTEYHVFDPEETLRELAEYTHYLPDSWKDRYHTEGVKQEFCELYNLRITVLLRELASLITTPFILWFSLPNSAGKMVDFFRESSVYVDGLGYVCKYAVYDGDADAVKKHFGTDGNETTEQDAATEEQDIDSEPDEATKKMMQSYMYFLDDYENDDNLLGKYQIPKKRRESFDNTQYDVSNSNQKNQDDDSDMILANRYTWRKQFKPGQKPELFRIGNHVLNDKTFTQQGSNHLGIDESYARSQISNTAEESNRSSLYNSKYKSPTKGVLGLVKEYYKKSDVGR
What is the function of this protein?
Phospholipid scramblase involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation.  Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome.  Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.  Required for mitophagy.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.
What are the official names of this protein?
Autophagy-related protein 9.
What is the protein family that this protein belongs to?
Belongs to the ATG9 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PANB_YERPP
Sequence: MKTTTMSQLRQWKQEKRKFATLTAYDASFAQLFAEQGIQVLLVGDSLGMTLQGFDSTLPVTVADMAYHTRAVRRGAPHCLLLADMPFMSYATPELAFTHAAELMRAGANMVKLEGGSWLCDTIRMLAERAVPVCGHLGLTPQSVNIFGGYKVQGREEVAANQLLQDAIALEQAGAQLLVLECVPVELAQRVTEELTIPVIGIGAGNVTDGQILVMHDALGITGGHTPKFSKNFLAHSAGDIRAAIKLYIEEVEGGIYPAEEHTFQ
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_LARHH
Sequence: MINDIKKTAESKMQKTIEAFKHTLAKVRTGRAHAGLLDHITVDYYGSDTPINQVANVTLIDARTIGVQVWEKNMAAKVEKAIRDSDLGLNPMSMGEVIRVPMPALTEERRRDLTKVVKGEAEDARVAVRNVRRDANNDLKTLLKDKDITEDEERRAQDDIQKLTDKYVAEVDKLFAEKEKELMAI
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_BURPS
Sequence: MSYRELVAELPREHAEALSDALVELGALSVSVEDADADTPDEQPLFGEPGLVPERTAWQHSRVIALVDATQDPAVLLAAAANEAGLARTPRFELREVEEQDWVRLTQSQFEPIHIGEKIWVVPSWHDAPQPDALVLELDPGLAFGTGSHPTTRLCMEWLEQTVQPGQTVLDYGCGSGILAILAKKCGAGRVTGIDIDPQAVEAARHNSERNRADVTYGLPDDCPDGEFDIVVANILSNPLKLMASMLASKVKPGGRIALSGVLARQADEVASVYARYIDIAVWREHEGWVCLAGTRRESH
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYLKC_DICDI
Sequence: MDRMDSSDEEIDNISDDELQSGDEIEVESSNSPLRLNYILGNEIGRGAFSIVREATSRATGTKVAIKSINTRFIKNKLLMREIEIMKKVGDHPNILKLYEVYETTKHLHLVLELVTGGELFDKIVQRGEYSEQDASKIVRQIVSAVGHLHANGIAHRDLKPQNLLCAGEEGDDIRVADFGLSKIFGDGDYLETCCGSPEYVAPEVLECKPYDKACDLWSVGVITYVLLTGCFPFWDKNNAVLYEKIRNVDYGWPEGLEVSNEAKDLVSHLIEKNPEKRFTFEQCLIHPWVTGEGVSNARKIKPFQQQQPNNR
What is the function of this protein?
May phosphorylate a specific serine in the N-terminus of a myosin light chain.
What are the official names of this protein?
Probable myosin light chain kinase DDB_G0282429.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
Protein: Y1265_PECAS
Sequence: MAYIDPTLLILLVLAGLGIISHNMTVTLAILVLLAIRITPLNSYFPWVEKYGLSIGIVVLTIGVMAPIASGKITASEVMHSFLHWKSLLAILIGVAVSWLGGRGVSLMSNQPSVVAGLLVGTVMGVALFRGVPVGPLIAAGLLSLLIGKT
What are the official names of this protein?
UPF0756 membrane protein ECA1265.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YPRB2_CORML
Sequence: MKFVMYPHLWESTTAVIEGGGHERVEDIKDADFIFFNGSAPEFPDLPENIKFVQASMAGIDALVKRGVVNEKARWANAAGLYADTVAESTIGLILAQMHMHAATRLAKSWSVRPEVENNKSWLHDNKTVAILGAGGIGVRLLEMLKPFNVKTIAVNNSGRPVEGADETFAMDKAEHVWAEADVFVLILPLTDATYQIVNAETLGKMKPSAVLVNVGRGPLINTDDLVDALNNGTIAGAALDVTDPEPLPDSHPLWEMDNVVITPHTANTNERIRALTGELTLRNIELFEAGEQMATEVDVVAGY
What are the official names of this protein?
Uncharacterized protein in proB 3'region.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Protein: RS11_CHLAB
Sequence: MVKHQAQKKGVKRKQLKNIPSGIVHVKATFNNTIVSITDPAGNTISWASAGKVGYSGSRKSSAFAATVAAQDAAKIAMNSGLKEVEVCLKGTGAGRESAVRALIAAGLVVSVIRDETPVPHNGCRPRKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: TNR1A_RAT
Sequence: MGLPIVPGLLLSLVLLALLMGIHPSGVTGLVPSLGDREKRDNLCPQGKYAHPKNNSICCTKCHKGTYLVSDCPSPGQETVCEVCDKGTFTASQNHVRQCLSCKTCRKEMFQVEISPCKADMDTVCGCKKNQFQRYLSETHFQCVDCSPCFNGTVTIPCKEKQNTVCNCHAGFFLSGNECTPCSHCKKNQECMKLCLPPVANVTNPQDSGTAVLLPLVIFLGLCLLFFICISLLCRYPQWRPRVYSIICRDSAPVKEVEGEGIVTKPLTPASIPAFSPNPGFNPTLGFSTTPRFSHPVSSTPISPVFGPSNWHNFVPPVREVVPTQGADPLLYGSLNPVPIPAPVRKWEDVVAAQPQRLDTADPAMLYAVVDGVPPTRWKEFMRLLGLSEHEIERLELQNGRCLREAHYSMLEAWRRRTPRHEATLDVVGRVLCDMNLRGCLENIRETLESPAHSSTTHLPR
What is the function of this protein?
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha.  The adapter molecule FADD recruits caspase-8 to the activated receptor.  The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis (By similarity).
What are the official names of this protein?
Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor 1, TNF-R1, Tumor necrosis factor receptor type I, TNF-RI, TNFR-I, p55, p60.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein.
Protein: RES18_BOVIN
Sequence: MQRQLWLGGFRGLWLLVCFLLLNSRLGGSSDVSGHDGQSQVGVGQLWPLPGFTTPVFKHLQVLLQQIMPHDLFWKDDMTQEVMTQKMGRTSKLHPEDPCVRSGPAAFPTRTPGVRGKQEEKLRLLFPKSPMVKVNKDQCFTSKVVSKVLKHEVANPVKGFFESPPTVGHNLVAD
What is the function of this protein?
May play an important regulatory role in corticotrophs.
What are the official names of this protein?
Regulated endocrine-specific protein 18.
What is the protein family that this protein belongs to?
Belongs to the RESP18 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Golgi apparatus. Cytoplasmic vesicle, secretory vesicle lumen. Note=Found in the lumen of secretory vesicles (dense core vesicles, DCV). However, seems to be retained intracellularly and not secreted.
Protein: URE2_SYNS9
Sequence: MAPLIPGELIPEPGELELNAGRPVTTISVANGGDRPVQVGSHFHFAEANAALQFDRDAARGQRLDIPAGTAIRFEPGDHRDVNLIPFAGHRRVIGFNGRINGPIDA
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF5A_METJA
Sequence: MPGTKQVNVGSLKVGQYVMIDGVPCEIVDISVSKPGKHGGAKARVVGIGIFEKVKKEFVAPTSSKVEVPIIDRRKGQVLAIMGDMVQIMDLQTYETLELPIPEGIEGLEPGGEVEYIEAVGQYKITRVIGGK
What is the function of this protein?
Functions by promoting the formation of the first peptide bond.
What are the official names of this protein?
Translation initiation factor 5A, Hypusine-containing protein, eIF-5A.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPLA_YERPS
Sequence: MSSLRLLISDSYDPWFNLAVEECIFRQMSPDQRVLFLWRNADTVVIGRAQNPWKECNTRRMEQDGVKLARRSSGGGAVFHDLGNTCFTFMAGKPGYDKTISTQIILNALASLGIQATASGRNDLVVINGEDERKVSGSAYKETKDRGFHHGTLLLNADLSRLADYLNPDPKKLQAKGITSVRSRVTNLVELLPGIDHEKIRTAIEQAFFAYYDEQVSAEVISPQSLPNLPGFTEQFAKQSSWEWNFGQAPAFSHVVDTRFTWGGIELHFDVLHGAIDRCQIFTDSLNPTPLEALAQRLQGAAYRPDAIDKICQHWIDDFPELQTELQQACHWLVEVLR
What is the function of this protein?
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
What are the official names of this protein?
Lipoate-protein ligase A, Lipoate--protein ligase.
What is the protein family that this protein belongs to?
Belongs to the LplA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUXS_ECO5E
Sequence: MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADVWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELALPKEKLQELHI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: GYRA_ARATH
Sequence: MTPVLCHSTASIPNPNSLMSLSSTLRLSSSLLRRSFFRFPLTDPLCRLRRTEPSATRFFSSRTPRSGKFVVGAGKRGDEQVKEESGANNGGLVVSGDESRIVPFELHKEATESYMSYALSVLLGRALPDVRDGLKPVHRRILFAMHELGMSSKKPYKKCARVVGEVLGKFHPHGDTAVYDSLVRMAQSFSLRCPLIQGHGNFGSIDADPPAAMRYTECRLDPLAEAVLLSDLDQDTVDFVANFDNSQKEPAVLPARLPALLLNGASGIAVGMATNIPPHNLGELVDVLCALIHNPEATLQELLEYMPAPDFPTGGIIMGNLGVLDAYRTGRGRVVVRGKAEVELLDPKTKRNAVIITEIPYQTNKATLVQKIAELVENKTLEGISDIRDESDRNGMRVVIELKRGGDPALVLNNLYRHTALQSSFSCNMVGICDGEPKLMGLKELLQAFIDFRCSVVERRARFKLSHAQQRKHIIEGIVVGLDNVDEVIELITKASSHSSATAALQSEYGLSEKQAEAILEITLRRLTALERKKFTDESSSLTEQITKLEQLLSTRTNILKLIEQEAIELKDRFSSPRRSMLEDSDSGDLEDIDVIPNEEMLMAVSEKGYVKRMKADTFNLQHRGTIGKSVGKLRVDDAMSDFLVCHAHDHVLFFSDRGIVYSTRAYKIPECSRNAAGTPLVQILSMSEGERVTSIVPVSEFAEDRYLLMLTVNGCIKKVSLKLFSGIRSTGIIAIQLNSGDELKWVRCCSSDDLVAMASQNGMVALSTCDGVRTLSRNTKGVTAMRLKNEDKIASMDIIPASLRKDMEEKSEDASLVKQSTGPWLLFVCENGYGKRVPLSSFRRSRLNRVGLSGYKFAEDDRLAAVFVVGYSLAEDGESDEQVVLVSQSGTVNRIKVRDISIQSRRARGVILMRLDHAGKIQSASLISAADEEETEGTLSNEAVEAVSL
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A, chloroplastic/mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Mitochondrion. Nucleus.
Protein: MOAA_CROS8
Sequence: MASQLTDAFARKFYYLRLSVTDVCNFRCTYCLPDGYKPAGVTNKGFLSLDEIRRVTRAFANLGTEKVRLTGGEPSLRRDFCDIIAAVRENPSIRQIAVTTNGYRLARDVAQWREAGLTAVNVSVDSLDARQFHAITGQDKFRQVMAGIDAAFDAGFEKVKVNTVLMRDVNHHQLDTFLNWIQSRPIQLRFIELMETGEGSDLFRKHHISGATIRDELLKRGWIHQLRSRADGPAQVFCHPDYQGEIGLIMPYEKDFCASCNRLRVSSVGKLHLCLFGDGGVDLRDLLAEEGQQAALMARIETALLGKKQTHFLHQGNTGITQNLSYIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: RIMM_DEHMB
Sequence: MTQEEYILIGKVLGVWGISGGLKIGVLTDFPERFDAGNELLVGRKLYTISQTNWQKAQVIVHLSGIDDIDTALELKDALVEIPASALKELPEGVYYDFQLIGLEVVDLSGVKIGQIKEILHMPSNDIYVSSYGVKEALIPAIKDVVKEINLKTGKIIIDPIPGLLD
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: N42L1_HUMAN
Sequence: MEDSFLQSFGRLSLQPQQQQQRQRPPRPPPRGTPPRRHSFRKHLYLLRGLPGSGKTTLARQLQHDFPRALIFSTDDFFFREDGAYEFNPDFLEEAHEWNQKRARKAMRNGISPIIIDNTNLHAWEMKPYAVMALENNYEVIFREPDTRWKFNVQELARRNIHGVSREKIHRMKERYEHDVTFHSVLHAEKPSRMNRNQDRNNALPSNNARYWNSYTEFPNRRAHGGFTNESSYHRRGGCHHGY
What are the official names of this protein?
NEDD4-binding protein 2-like 1.
Protein: HUTU_PSEA7
Sequence: MTTPSKFRDIEIRAPRGNTLTAKSWLTEAPLRMLMNNLDPEVAENPKELVVYGGIGRAARNWECYDRIVETLRQLNDDETLLVQSGKPVGVFKTHADAPRVLIANSNLVPHWATWEHFNELDARGLAMYGQMTAGSWIYIGSQGIVQGTYETFVEAGRQHYDGNLAGRWVLTAGLGGMGGAQPLAATLAGACSLNIECQQSRIDFRLRSRYVDEQAKDLDDALARIARYTAEGKAISIALLGNAAEILPELVRRGVRPDMVTDQTSAHDPLNGYLPAGWTWEQYRDRAQTDPAGVVKAAKRSMAVHVQAMLAFQKLGIPTFDYGNNIRQMAKEEGVANAFDFPGFVPAYIRPLFCRGIGPFRWAALSGDPQDIYKTDAKVKELIPDDAHLHRWLDMARERISFQGLPARICWVGLGLRAKLGLAFNEMVRSGELSAPIVIGRDHLDSGSVSSPNRETEAMQDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHSGMVIVCDGTDAAAARIARVLTNDPGTGVMRHADAGYPIAIDCAREQGLNLPMITGKR
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_LISIN
Sequence: MAKKVIKEVKLQIPAGKANPAPPVGPALGQAGVNIMGFCKEFNARTADQAGLIIPVVITVFEDRSFTFITKTPPAAVLLKKAAKVEKGSGEPNKTKVASVTRAQVQEIAETKMPDLNAANVESAMLMVEGTARSMGITIQD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: ASPD_ACIAD
Sequence: MKQLMMIGFGAMASEVYAHLPQDLELKWIVVPERSVESVKQKVDRHIQVISDINQCDGAPDYVIEVAGQAAVKEHAKNVLAHGWNIGLISVGTLADSEFFTELQQTAEQNGAHLHLLAGAIAGIDGIAAAKEGGLEKVTYKGCKSPNSWRGSYAEQLIDLDQVHTVTMFYRGTAREAAQKFPANANVAATIALAGVGMDNTIVELTVDPDTTQNKHTIVAEGRFGQMTIEMVGVPLASNPKTSTLAALSVIRACRNSVEAIQI
What is the function of this protein?
Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
What are the official names of this protein?
L-aspartate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the L-aspartate dehydrogenase family.
Protein: OSH1_YEAST
Sequence: MEQPDLSSVAISKPLLKLKLLDALRQGSFPNLQDLLKKQFQPLDDPNVQQVLHLMLHYAVQVAPMAVIKEIVHHWVSTTNTTFLNIHLDLNERDSNGNTPLHIAAYQSRGDIVAFLLDQPTINDCVLNNSHLQAIEMCKNLNIAQMMQVKRSTYVAETAQEFRTAFNNRDFGHLESILSSPRNAELLDINGMDPETGDTVLHEFVKKRDVIMCRWLLEHGADPFKRDRKGKLPIELVRKVNENDTATNTKIAIDIELKKLLERATREQSVIDVTNNNLHEAPTYKGYLKKWTNFAQGYKLRWFILSSDGKLSYYIDQADTKNACRGSLNMSSCSLHLDSSEKLKFEIIGGNNGVIRWHLKGNHPIETNRWVWAIQGAIRYAKDREILLHNGPYSPSLALSHGLSSKVSNKENLHATSKRLTKSPHLSKSTLTQNDHDNDDDSTNNNNNKSNNDYDDNNNNNNNDDDDYDDDDESRPLIEPLPLISSRSQSLSEITPGPHSRKSTVSSTRAADIPSDDEGYSEDDSDDDGNSSYTMENGGENDGDEDLNAIYGPYIQKLHMLQRSISIELASLNELLQDKQQHDEYWNTVNTSIETVSEFFDKLNRLTSQREKRMIAQMTKQRDVNNVWIQSVKDLEMELVDKDEKLVALDKERKNLKKMLQKKLNNQPQVETEANEESDDANSMIKGSQESTNTLEEIVKFIEATKESDEDSDADEFFDAEEAASDKKANDSEDLTTNKETPANAKPQEEAPEDESLIVISSPQVEKKNQLLKEGSFVGYEDPVRTKLALDEDNRPKIGLWSVLKSMVGQDLTKLTLPVSFNEPTSLLQRVSEDIEYSHILDQAATFEDSSLRMLYVAAFTASMYASTTNRVSKPFNPLLGETFEYARTDGQYRFFTEQVSHHPPISATWTESPKWDFYGECNVDSSFNGRTFAVQHLGLWYITIRPDHNISVPEETYSWKKPNNTVIGILMGKPQVDNSGDVKVTNHTTGDYCMLHYKAHGWTSAGAYEVRGEVFNKDDKKLWVLGGHWNDSIYGKKVTARGGELTLDRIKTANSATGGPKLDGSKFLIWKANERPSVPFNLTSFALTLNALPPHLIPYLAPTDSRLRPDQRAMENGEYDKAAAEKHRVEVKQRAAKKEREQKGEEYRPKWFVQEEHPVTKSLYWKFNGEYWNKRKNHDFKDCADIF
What is the function of this protein?
Lipid transport protein (LTP) involved in non-vesicular transfer of lipids between membranes.  Functions in phosphoinositide-coupled directional transport of various lipids by carrying the lipid molecule in a hydrophobic pocket and transferring it between membranes through the cytosol.  Involved in maintenance of intracellular sterol distribution and homeostasis (PubMed:8017104, PubMed:11238399, PubMed:15173322).  Involved in non-vesicular transport of ergosterol and PI(4)P at the NVJ.  Binds sterol and PI4P in a mutually exclusive manner (PubMed:28319008).  May be involved in formation of PMN vesicles by altering the membrane lipid composition (PubMed:15173322).
What are the official names of this protein?
Oxysterol-binding protein homolog 1, Oxysterol-binding protein-related protein 1, ORP 1, OSBP-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the OSBP family.
What are the subcellular locations of this protein?
Golgi apparatus membrane. Nucleus outer membrane. Endoplasmic reticulum membrane. Vacuole membrane. Note=Soluble protein that accumulates on the surface of late Golgi membranes and at nucleus-vacuole (NV) junctions, interorganelle interfaces between the nuclear envelope and the vacuole membrane formed during piecemeal microautophagy of the nucleus (PMN). Targeted exclusively to NV junctions in stationary phase.
Protein: METXA_PSYTT
Sequence: MPEIFKYQDPFQLENGEVLPELEVSYSTLGKLNKEKSNVIWVCHALTANAQPEDWWRGLIGNEKGIDTEKYFIVCANIIGSCYGSTNPKSINPETGEVYGLNFPLFSIRDVTKSLELLSEALEIEHIQFLIGGSMGGMQAMEWAIEKPDKIKNLILLATNAKHSSWGIALNETQRMAIEADSTFYKKETNSGKKGLEAARAIALLSYRNYNTYRHTQVDQEHTADHFRASTYQKYQGEKLSKRFNAKCYWYLSKAMDSHNVGRNRGDCKKALAKIKAETLVIAVQSDLLFPVEEQRFLAQYIPKGKLEIIDSIYGHDGFLIEVEKIKSLVHKHFKL
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNTB_SALPA
Sequence: MEAIKGSDVNVPDAVFAWLLDGRGGVKPLEDNDVIDSQHPCWLHLNYTHPDSARWLASTPLLPNNVRDALAGESSRPRVSRMGEGTLITLRCINGSTDERPDQLVAMRLYMDERFIVSTRQRKVLALDDVVSDLQEGTGPVDCGGWLVDVCDALTDHASEFIEELHDKIIDLEDNLLDQQIPPRGFLALLRKQLIVMRRYMAPQRDVYARLASERLPWMSDDHRRRMQDIADRLGRGLDEIDACIARTGIMADEIAQVMQESLARRTYTMSLMAMVFLPSTFLTGLFGVNLGGIPGGGWRFGFSLFCILLVVLIGGVTLWLHRSKWL
What is the function of this protein?
Zinc transporter.  Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake.
What are the official names of this protein?
Zinc transport protein ZntB.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL2_BRUA4
Sequence: MALKHFNPITPGQRQLVIVDRSGLYKGKPVKSLTEGLSKKGGRNNTGRITVRFQGGGHKRTYRFIDFKRRKLDVVGTVERLEYDPNRTAFIALIRYEDGELAYILAPQRLAVGDKVVAGNSVDVKPGNAMPLASMPVGTIVHNVELKPGKGGQIARSAGTYAQLVGRDQGMAILRLNSGEQRLVPGACFASVGAVSNPDHGNINDGKAGRSVWRGKRPHVRGVAMNPVDHPHGGGEGRTSGGRHPVTPWGKPTKGKKTRSNKSTDKFIMRSRHQRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RS5_PYRAE
Sequence: MRVKAKIFIRPLFATYVSVIDLSLWEPRTELGRMVKEGKIRTIDEIFANNYIIKEPEIVDILLPGLKQELLNVNLVQRQTHAGERNQFQAVVAVGNEDGYVGVGIGKARQVRQAIEKATREAKLNLVPVRRGCGSWKCSCDEPHSVPFVVRGKSGSVEITLIPAPKGVGLVAGDVAKAVLRLAGIKDVWTKTRGDTRTTLNFAMAVYNALRNTYYFKI
What is the function of this protein?
With S4 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: AROA_PSEU2
Sequence: MRPQATLTVLPVERPLVGRVSPPGSKSITNRALLLAGLAKGTSRLTGALKSDDTRVMSEALRLMGVQVDEPDDSTFVVTSSGHWQAPQQALFLGNAGTATRFLTAALANFEGDFVVDGDEYMRKRPIGPLVDALQRMGVEVSAPSGCPPVAIKGKGGLEAGRIEIDGNLSSQYVSALLMAGACGKGPVEVALTGSEIGARGYLDLTLAAMRAFGAEVQAIGDAAWKVSATGYRATDFHIEPDASAATYLWAAQALTEGAIDLGVASNAFTQPDALASQIIASFPNMPAVIDGSQMQDAIPTLAVLAAFNRQPVRFVGIANLRVKECDRISALSNGLCAIAPGLAVEEGDDLIVTANPTLAGTTVDALIDTHSDHRIAMCFALAGLKIAGIRILDPDCVAKTYPGYWDALASLGVSVQR
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_ECOLI
Sequence: MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLTAIKPGMIRIVKQHGHEEFIYLSGGILEVQPGNVTVLADTAIRGQDLDEARAMEAKRKAEEHISSSHGDVDYAQASAELAKAIAQLRVIELTKKAM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.