PharMolix/UniProtQA huggingface dataset:
Protein: MBD_THEVO
Sequence: MNIMEISKFQSLGDKIRTMLEDHGYLSENNDYEPNPIDGNISISYAYPIKAFEKFLGYYDVENRVAYNPSISMRTDFSYCIAACRYNKNGNEDTVILDGVTDEKYLRKAKFALDYFRKEFRIKGSFDFYIRRYRRYTKAKGLSESSAVAAAVSRALIKNVFGEGPALDDVFVSKYARLVSGSGTRAAHSGISIWLSYPGINLRECAAFRVADDPHDVYYGIFPKYTDIATDSAHSVAVKSIFYASWLEDKYANIKRLIEHNFDIDELLISGENDMLKLNAILFSGGLIIQTGESLRILRAIQDFKKNGDLFFTADTGPSIMVLSRDKSLIEELRQSVEDPYIEGTYNFNRHTRDLNNFTKEANEYFLENKIE
What is the function of this protein?
Catalyzes the ATP-independent decarboxylation of (R)-mevalonate 3,5-bisphosphate to isopentenyl phosphate.  Functions in an alternative mevalonate pathway, only present in extreme acidophiles of the Thermoplasmatales order, which passes through mevalonate 3-phosphate rather than mevalonate 5-phosphate.
What are the official names of this protein?
Mevalonate 3,5-bisphosphate decarboxylase, MBD, Bisphosphomevalonate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the mevalonate 3,5-bisphosphate decarboxylase family.
Protein: YQDA_CAEEL
Sequence: MDSPSTSESPLKKNTIQDFGESNMTESPQSKEEIDEPEEECSVCKNEIIDTTSLSDCCHEFCYDCIVGWLTKGSGPFCPMCKTPVSFIQRKGTDEKITVQQIKSEGEPAATASEDLVTEKRIVSRKIRSCRRLMNQIDEIIGATSSRSDSQKRKPRLEELNSMKQLCVSQLNSLQMLRDDIDHGAAKALIVSKAAFRRLIYERQVISEGLPDATNSLSKTEFRDNIDHYRAVLHSFLSVELKSLPAKTQPRVDNENSWYFYTLHDVAEGKDEEIINRIFSMIEDRGTRDLNAREVDAALNGLVSCRVVIAFIAELKSLINSRKSFLEWCGAITYRIRTDRGGESAGNDVVTVDDSIELEPEENRSNHRSRRFPVFTPFDRVFGSTMGHMYRGQPQAPLRLGPNATNPFRPAPLPVPSQLPIAGIPWAELTTSSAGAGSARSRGSDSVVEIDDDDDNDGVDVDDDDREDSDEPRTYSNSEEDSDEEIQVVERDDTIILDDSNRSLPKPVANGSADRKRKYEFPLEDHWKKAKTSQLPEGLVDDVQELIAKYNMPLTQSMNMLVGAAQEAIIRINKPMPSTSSAPDISKFKPDDMLQLASYLSRTGALSRRQ
What are the official names of this protein?
Uncharacterized RING finger protein C32D5.10.
Protein: MTB2_BACAM
Sequence: MKENIGDCTIDLTVTSPPYDDLRNYNGYSFNFEETAQELYRVTKEGGVVVWVVGDKTHKGSETGSSFRQALYFKELGFNLHDTMIYEKDSISFPDKNRYYQIFEYMFIFSKGKPKTINLLADRKNKWYNGKKHIKGHYRKMDGEKVRHHKQNLLKEFGVRFNIWRIPNGHQKSTLDKIAFQHPAIFPEKLAEDHILSWSNEGDIVFDPFMGSGTTAKMAALNNRKYIGTEISKEYCDIANERLKNYIILHKRMEGKGYRLPQVHS
What is the function of this protein?
A beta subtype methylase, recognizes the double-stranded sequence 5'-GGATCC-3', methylates C-? on both strands.  No endonuclease has been identified for this methylase, although it is speculated it might protect against BamHI.
What are the official names of this protein?
Orphan methyltransferase M.BamHII, M.BamHII, Modification methylase BamHII, N(4)-cytosine-specific methyltransferase BamHII.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.
Protein: MTAD_CALS4
Sequence: MNLLIKNVNLLSMEEDKVLEGVNVYVEGDTIKHIGELLPDVKVDVVIEGKDKLAMPGLINAHTHLGMSLFRNYANDVPLFDWLTKYIWPLEARLTAEDVYWGSLLSMIEMIYSGTTTYCDMYFFMEEVAKATEEIGIRGVISRGIIEEQDAKVNEEKLKDTENLYNAWNGKAEGRIKVMVGPHAPYTCGPTYLKEILDLAKRLGTGIHIHVSETKREVEESLEKYGKTPVQHLKDLGIFEVPTVAAHCVHLTDEDIEVLKEMKVSPVYNPTSNLKLASGFAPVEKMLKKGINVALGTDGPASNNNLNMFEEIHFAATINKALNEDALSVPAFEALKMATVSGARALLWEREIGTIEVGKKADVILIDLNKPHLHPKNDLISALAYSVQGSDVDTVIVNGKVIMEKREIKTVDVERVYYEVEKRAQNLIRGEIS
What is the function of this protein?
Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively.  Is also able to deaminate adenosine.
What are the official names of this protein?
5-methylthioadenosine/S-adenosylhomocysteine deaminase, MTA/SAH deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
Protein: ACCA_PARL1
Sequence: MHTYLDFEKPIAELEGKVQELKLLAQEDPSVSIGDEVSKLEQKAAQLLQETYASLTPWQKVQVARHPARPHFLDYVERLVEDFTPLAGDRLYGEDSAIVGGLGRFRGRSVMFIGHEKGSDTQGRIKHNFGMARPEGYRKAIRLMTLAERFGIPVVTLADTSGAYPGMESEERSVAEAIARSTDRCLSLGVPLISVVIGEGMSGGAIGIACGNRVLMLEHSIYSVISPEGASSILWRSSDKTKDAATAMKITAQHLHELGVIDRVLPEPVGGAHRERNQMIKETGDAIAEELKGLEKLDADSIRRVRREKFLAMGRIGFS
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPR_PHOLL
Sequence: MTTNHLTDPALSPQDHEDWQCFVTLLQQAFAENLQHPILQLLLTPDERTALATRVRIIKELMSGKMSQRELKNELGVGIATITRGSNSLKFASNDVKAWLEQQLLK
What is the function of this protein?
This protein is an aporepressor.  When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription.  The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
What are the official names of this protein?
Trp operon repressor.
What is the protein family that this protein belongs to?
Belongs to the TrpR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJZC_BACSU
Sequence: MGQQHQFRPGQKAPNNGVYVEIGETGSMVKNPQKVHLSAGEMFPETSNHNRLWTYKRKP
What are the official names of this protein?
Uncharacterized protein YjzC.
Protein: IOVO_MELOE
Sequence: LAAVSVDCSEYPKPACTLEYRPLCGSDNKTYGNKCNFCNAVVESNGTLTLSHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: SPXH_STAAR
Sequence: MAGELRIMENKSREDINLSPVSKIEIYSFFDPFSSDCFKLSAILSKLRIEYNQYIRIRHILNPSLKVLTKCQAQSTSNFDNIALAYKAAELQGRLRAERFIHLMQNEIIPKRDIITKSMICDCIQNAGIDLEVFKDDLQKSKLTESLKIDLHIAREMEIEQAPSLVFFSEDVHEEGLKVEGLYPYHIYTYIINELMGKPIEKNLPPKLETYIQQQQLVTMEELLTIYEWPEKLLNKELKKLAIQQKIEKLKYPDGDFWKSKMPKIKSK
What is the function of this protein?
Adapter protein required for efficient degradation of Spx by ClpXP under non-stress conditions.  Interaction with Spx stabilizes Spx and exposes the C-terminus of Spx for recognition and proteolysis by ClpXP.
What are the official names of this protein?
ClpXP adapter protein SpxH.
What is the protein family that this protein belongs to?
Belongs to the SpxH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_MYCA1
Sequence: MDDSNDSSSAGPDGRLHAVDPSLTERQRTILNVIRASVTSRGYPPSIREIGDAVGLTSTSSVAHQLRTLERKGYLRRDPNRPRAVDVRGVDDDVAAPATEVAGSDALPEPTFVPVLGRIAAGGPILAEEAVEDVFPLPRELVGDGTLFLLKVVGDSMVEAAICDGDWVVVRQQHVADNGDIVAAMIDGEATVKTFKRAGGQVWLMPHNPAFDPIPGNDATVLGKVVTVIRKV
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: MDTC_ECO8A
Sequence: MKFFALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRTAISNANVRKPQGALEDGTHRWQIQTNDELKTAAEYQPLIIHYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVVVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMCGWMLKASKPREQKRLRGFGRMLVALQQGYGKSLKWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPRDERSETAQQIIDRLRVKLAKEPGANLFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKPKQTVTE
What is the function of this protein?
The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtC, Multidrug transporter MdtC.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RSBV_STAAR
Sequence: MNLNIETTTQDKFYEVKVGGELDVYTVPELEEVLTPMRQDGTRDIYVNLENVSYMDSTGLGLFVGTLKALNQNDKELYILGVSDRIGRLFEITGLKDLMHVNEGTEVE
What is the function of this protein?
Positive regulator of sigma-B activity.  Non-phosphorylated RsbV binds to RsbW, preventing its association with sigma-B.  When phosphorylated, releases RsbW, which is then free to complex with and inactivate sigma-B (By similarity).
What are the official names of this protein?
Anti-sigma-B factor antagonist, Anti-anti-sigma-B factor.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor antagonist family.
Protein: DNLJ_STRPB
Sequence: MKKRIKELTDLLNRYRYDYYTKDAPSVSDSDYDKLYRELVTLEQSYPEYVLQDSPTQQVGGTILKGFEKYRHQYPLFSLQDAFSREELDAFDKRVKAEFPNATYLAELKIDGLSISLSYENGFLQVGATRGDGNIGENITENIKKIKDIPHQLSEPLTITVRGEAYMSRQSFKAINEARQENGETEFANPRNAAAGTLRQLDTSVVAKRQLATFLYQEASPTARNQQNEVLAELAGLGFSVNPYYQLTSSMDEIWDFIKTIEAKRDQLAYDIDGVVIKVNSLAMQEELGFTVKAPRWAIAYKFPAEEKEAEILSVDWTVGRTGVVTPTANLTPVQLAGTTVSRATLHNVDYIAEKDIRIGDTVIVYKAGDIIPAVLNVVMSKRNQQEVMLIPKLCPSCGSELVHFEDEVALRCINPLCPSLIQRSLEHFASRDAMNITGLGPAIVEKLFLAGFVHDVADIYQLTKENFMQLDGIKEKSADKLLAAIEASKSNSAEKLLFGLGIRHIGSKVSRLILEVYGDISALLTAKEEEIARIDGLGSTIAQSLTQYFEQKTAAILVDELKTAGVNMHYSGQKVNSDAALFGLTVVLTGKLNQLNRNEAKDKLEALGAKVTGSVSKKTDLVIAGSDAGSKLEKAKSLGIRIEDEDWLRQL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: NUDT3_HUMAN
Sequence: MMKLKSNQTRTYDGDGYKKRAACLCFRSESEEEVLLVSSSRHPDRWIVPGGGMEPEEEPSVAAVREVCEEAGVKGTLGRLVGIFENQERKHRTYVYVLIVTEVLEDWEDSVNIGRKREWFKIEDAIKVLQYHKPVQASYFETLRQGYSANNGTPVVATTYSVSAQSSMSGIR
What is the function of this protein?
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate) and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction (PubMed:10419486, PubMed:12370170, PubMed:9822604, PubMed:10585413).  InsP6 (inositol hexakisphosphate) is not a substrate (PubMed:9822604).  Acts as a negative regulator of the ERK1/2 pathway (By similarity).  Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with diadenosine 5',5'''-P1,P6-hexaphosphate (Ap6A) and diadenosine 5',5'''- P1,P5-pentaphosphate (Ap5A) being the preferred substrates (PubMed:12370170).  The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A (PubMed:12370170).  Also able to hydrolyze 5-phosphoribose 1-diphosphate (PubMed:12370170).  Acts as a decapping enzyme that modulates the stability of a subset of mRNAs implicated in cell motility (PubMed:26932476).
What are the official names of this protein?
Diphosphoinositol polyphosphate phosphohydrolase 1, DIPP-1, Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1, Nucleoside diphosphate-linked moiety X motif 3, Nudix motif 3.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. DIPP subfamily.
Protein: MNME_SYNC1
Sequence: MINDDTIVAPATAPGEGGIGIVRLSGSGAEKLLLKFFSPRRFCERLDSHFLYYGKFTDETGKIVDEVMAVIMRKPRSYTREDVVEIHCHGGGLLVRSIIDVFLAAGARLARPGEFTLRAFLNGRIDLTQAEAVIDLIRSRSNLASDVALSQLEGRLAQQIGVFGQVIADLLAQVEAAIDFPEEDIELDDQQMLGASAGALIADMDRIIDTFESGRVLREGLRVLIFGKPNVGKSSLMNGLLGEARAIVTDIPGTTRDTIEEDLVLGGLPLRIVDTAGIRNTLDPVEEEGVRRARSKVESADLVLLVIDGSQEMGEDDLLALEFCRNREVLVVINKCDLATLPISSALDGLPYVRTSVLEKNGLDGLVSAIQERFVHNAHVAENRETVVLTQRRHRQALVKARQSLGRFRETLVQGMSPEFGAVELRDALDAVGEITGETTPDDILERIFTRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSU1_ARATH
Sequence: MANRGGCVTVAAEEMDELRRRNIELSREVAEMKTEMIKLWQRTVVAEEAEEQLCSQLAELEVESLEQARDYHDRMLFLMDQISRLSSSSVVSSS
What are the official names of this protein?
Protein RESPONSE TO LOW SULFUR 1.
Protein: DLGD_SALEP
Sequence: MKVTFEELKGAFYRVLRSRNIAEDTADACAEMFARTTESGVYSHGVNRFPRFIQQLDNGDIIPDAKPQRVTSLGAIEQWDAQRAIGNLTAKKMMDRAIELASDHGIGLVALRNANHWMRGGSYGWQAAEKGYIGICWTNSIAVMPPWGAKECRIGTNPLIVAIPSTPITMVDMSMSMFSYGMLEVNRLAGRELPVDGGFDDNGQLTKEPGVIEKNRRILPMGYWKGSGLSIVLDMIATLLSNGSSVAEVTQENSDEYGVSQIFIAIEVDKLIDGATRDAKLQRIMDFITTAERADDNVAIRLPGHEFTKLLDDNRRHGITIDDSVWAKIQAL
What is the function of this protein?
Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.
What are the official names of this protein?
2,3-diketo-L-gulonate reductase, 2,3-DKG reductase, 3-dehydro-L-gulonate 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH2/MDH2 oxidoreductase family. DlgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCPG1_PONAB
Sequence: MSENSSDSDSSCGWTVISHEGSDIEMLNSVTPTNSCEPAPECSSLEQEELQALQLEQGESSQNGTVLMEETAYPALEETSSTIEAEEEKIPEDNIYIGTASDDSDIVTLEPPKLEEIGNQEVVIVEEAQSSEDFNMGSSSSSQYTFCQPETVFSSQPSDDESSSDETSNQPSPAFRRRRARKKTVSTSESEDRLVAEQETEPSKESKRQFSSGLNKCVILALVIAVSMGFGHFYGTIQIQKRQQLVRKIHEDELNDMKDYLSQCQQEQGSFIDYKSLKENLARCWTLTEAEKMSFETQKTNLATENQYLRVSLEKEEKALSSLQEELNKLREQIRILEDKGTSTELVKENQKLKQHLEEEKQKKHSFLSQRETLLTEAKMLKRELERERLVTTALRGELQQLSGSQLHGKSDSPNVYTEKKEIAILRERLTELERKLTFEQQRSDLWERLYVEAKDQSGKQETDGKKKVGRGNHRAKNKSKETFLGSVKETFDAMKNSTKEFVRHHKEKIKQAKEAVKENLKKFSDSVKSTFRHFKDTTKNIFDEKGNKRFGATKAAAEKPRTVFSDYLHPQYKAPTENHHNRGPTMQNDGRKEKPVHFKEFRKNTNSRKCSPGHACRENSHSFRKACYGVFDCAQQESISLFNTVVNPIRMDEFRQIIQRYMLKELDTFCHWNELDRFINKFFLNGVFIHDQKLFTDFVNDVKDYLRNMKEYQVDNDGVFEKLDEYIYRHFFGHTFSPPYGPSRPDKKQRMVNIENSRHRKQEQKHLQPQPYKREGKWHKYGRTNGRQMANLEIELGQLPFDPQY
What is the function of this protein?
Acts as an assembly platform for Rho protein signaling complexes.  Limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability and its transforming activity.  Does not inhibit activity of MCF2L toward CDC42, or activity of MCF2 toward either RHOA or CDC42.  May be involved in cell cycle regulation (By similarity).
What are the official names of this protein?
Cell cycle progression protein 1.
What is the protein family that this protein belongs to?
Belongs to the CCPG1 family.
What are the subcellular locations of this protein?
Cytoplasmic granule membrane; Single-pass type II membrane protein.
Protein: NTF3_PIG
Sequence: MSILFYMIFLAYLRGIQGNSMDQRRLPEDSLNSLIIKLIQADILKNKLSKQMVDLQENYQSTLPKAEAPREPERGEPAKSEFQPVTAVGPEWLRHHRRYNSPRVLLSDSTPLEPPPLYLVEDYVGNPSVANRTARRKRYAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYFRALTSYNNKLVGWRWIRIDTSCVCALSRKIGRT
What is the function of this protein?
Seems to promote the survival of visceral and proprioceptive sensory neurons.
What are the official names of this protein?
Neurotrophin-3, NT-3.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1967_STAA9
Sequence: MSFVTENPWLMVLTIFIINVCYVTFLTMRTILTLKGYRYIAASVSFLEVLVYIVGLGLVMSNLDHIQNIIAYAFGFSIGIIVGMKIEEKLALGYTVVNVTSAEYELDLPNELRNLGYGVTHYAAFGRDGSRMVMQILTPRKYERKLMDTIKNLDPKAFIIAYEPRNIHGGFWTKGIRRRKLKDYEPEELESVVEHEIQSK
What are the official names of this protein?
UPF0316 protein SaurJH9_1967.
What is the protein family that this protein belongs to?
Belongs to the UPF0316 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: 6PGL_SALPC
Sequence: MKQTVYTASPESQQIHVWSLNHEGTLTLVQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGVLTFAAESALPGSPTHISTDHHGRFVFVGSYNAGNVSVTRLQDGLPVELVDVVEGLDGCHSANITPDNRTLWVPALKQDRICLFTLSDDGHLVAQEPAEVNTVEGAGPRHMVFHPNRQYAYCVNELNSSVDVWQLKNPHGEIECVQTLDMMPADFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSVEGFQPTEVQPRGFNIDNSGKYLIAAGQKSHHIAVYEITGTQGLLTEKGRYAVGQGPMWVVVNAY
What is the function of this protein?
Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6-P-gluconolactonase.
What is the protein family that this protein belongs to?
Belongs to the cycloisomerase 2 family.
Protein: TGB2_PVXCP
Sequence: MSAQGHRLTAPVNSEKVYIVLGLSFALISITFLLSRSNLPHVGDNIHSLPHGGAYRDGTKAVLYNSPNFGSRTSLSNGKNAAFAVVLLLSLLIYGSRCLSQRNHLCACGNNHSSH
What is the function of this protein?
Plays a role in viral cell-to-cell propagation, by facilitating genome transport to neighboring plant cells through plasmosdesmata,.
What are the official names of this protein?
Movement protein TGB2, 12 kDa protein, Triple gene block 2 protein, TGBp2.
What is the protein family that this protein belongs to?
Belongs to the Tymovirales TGBp2 protein family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane.
Protein: APOA1_MICOH
Sequence: MKAVVLAVAVLFLTGSQARHFWQQDEPPQSSWDRVKDFATVYVDAVKDTGRDYVSQFETSALGKQLNLNLLENWDTLGSSVGRLQEQLGPVTQEFWDNLEKDTDWLRQEMNKDLEDVKTKVQPYLDQFQSKWQEEVARYRQKVEPLGAELREGARQKLQELQEKLAPVGEDLRDRMRQHVDTLRTKLAPYSDKMRDRLAERLAQLKDSATLAEYHTKATEHLKTFSEKAKPALEDLRQGVMPMLESFRVRLMSMIDEASKKLSAQ
What is the function of this protein?
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT).  As part of the SPAP complex, activates spermatozoa motility.
What are the official names of this protein?
Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.
Protein: BETB_CERS1
Sequence: MRAQPAASHFVDGRPLEDETGAPIPVIYPATGEEIARLHEATPAVIEAALASGARAQAAWAAMRPVERARILRRASDLIRARNEELSLLETLDTGKPLQETLVADWASGADALEFFAGLAPAVTGETVPLGQDFVYTIREPLGLCVGIGAWNYPSQIACWKAAPALALGNAMVFKPSEVTPLGALKLAEILIEAGLPPGLFNVVQGRGAVGAALVTDSRVAKVSLTGSVPTGRRVYAAAAEGVRHVTMELGGKSPLIVFDDADLESAIGAAMLGNFYSAGQICSNGTRVFVQKGIKEAFLARLAERADAIRMGDPLDPEVQMGPLVSQAQLEKVLAYIEKARAEGGRLVCGGEASVSPGCYVQPTVFADVTDAMTLAREEVFGPVMAVLDFETEEEAIARANATDFGLAAGVFTADLTRAHRVVAQLQAGTCWINAYNLTPVEAPFGGVKLSGVGRENGRAAVEHYTQVKSVYVGMGPVDAPY
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: TPPC5_HUMAN
Sequence: MEARFTRGKSALLERALARPRTEVSLSAFALLFSELVQHCQSRVFSVAELQSRLAALGRQVGARVLDALVAREKGARRETKVLGALLFVKGAVWKALFGKEADKLEQANDDARTFYIIEREPLINTYISVPKENSTLNCASFTAGIVEAVLTHSGFPAKVTAHWHKGTTLMIKFEEAVIARDRALEGR
What is the function of this protein?
May play a role in vesicular transport from endoplasmic reticulum to Golgi.
What are the official names of this protein?
Trafficking protein particle complex subunit 5.
What is the protein family that this protein belongs to?
Belongs to the TRAPP small subunits family. BET3 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network. Endoplasmic reticulum.
Protein: KCY_SHEON
Sequence: MSERAPVVTIDGPSGAGKGTISQLLAKHLGWQLLDSGAIYRVLALAAIHHDVELENEESITLLASHLDVKFLTGNEKDPVQVILEGEDVTTAIRTQECSNAASKVAAFPRVREALLRRQRAFRTAPGLIADGRDMGTVVFPTASAKLYLTASAQERAQRRYNQLQDKGFDVNIERLLAEIIERDDRDMNRPVAPLVPAENALVIDTSDKGIDEVLELALNYINQKLSSTN
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_BIFLO
Sequence: MSETTDYGASNTGANEESLRMVSSQPIGNEPVSDEELRPHVLGGFIGQPRLKAQLQLFLDAARKRDVPPDHILLAGPPGLGKTTLAMIVANELEVPIRVTSGPAVQHAGDLASILSSLDVGEVLFIDEIHRLPRAAEELLYIAMEDFRVDVMVGKGPGASSIPLTLPRFTVIGATTREGMLPSPLRARFGFTAHLDFYPHEELEKLIERSANVLGVNLDTGSAHELALRSRGTPRIANRLLRRVRDWAIVHDLIVVRPDDVKEALALYQIDSEGLDRLDIAVLNAIVRNFNGGPVGLNNLAAMVGEESETVETVCEPYLVREGFMIRTPKGRVATEKAWQHLGITPKDDVSKLF
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RS12_SACD2
Sequence: MATINQLVRKPRKRKVQKSDVPALQACPQRRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGSLDTSGVSDRKQGRSKYGTKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RL23_MOOTA
Sequence: MRTPEEIIIRPLVTEKSTGLMADNKYTFLVDPGANKIEIKHAIEKLFNVKVLKVNTLMERGKLRRVGRFQGRQSDRKKAIVTLRPGDKIQVFEGLE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.