PharMolix/UniProtQA huggingface dataset:
Protein: MTF1_SCHPO
Sequence: MKLPKILYDAAAFGGPRSTGFVKILNLNGRSSYKSSYLVNQNLMDEALVKSNLLKEYNSEKMTILEMAPGPGVTTTSLFNYFQPKSHVVLESREVFSKPLQKLCTLSDGRIKWVHQDGYYWQTYEDVYVSKVLDPRIQTEEEQKLSPHRELLFFAHLPHGYAGLLFVSQILDFLSARDWLGIFGRVRVLLWLPCSPTVTLLGSRGFSKRSKTSVFREAFTDSRVLAASESTLQKLCMGYSKEAKENYQISPNPLLVSPTPITSEPHKEDLTLVEMCSKPQDKQLSIPVFESIVRILLTCKATSLSKSIYYLGPGAETLLPSFTQCGINIDMPVGLLSAADFLTISKIIQKYPFKHHLHLGTIIEDS
What is the function of this protein?
Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase.  Interacts with DNA in a non-specific manner.
What are the official names of this protein?
Mitochondrial transcription factor 1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: HIS4_ECOLU
Sequence: MIIPALDLIDGTVVRLHQGDYGKQRDYGNDPLPRLQDYAAQGAEVLHLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQVGGGVRSEEDVAALLEAGVARVVVGSTAVKSPEMVKGWFERFGADALVLALDVRIDEQGNKQVAVSGWQENSGVSLEQLVETYLPVGLKHVLCTDISRDGTLAGSNVSLYEEVCARYPQVAFQSSGGIGNINDVAAMRGTGVRGVIVGRALLEGKFTVKEAIACWQNA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_LACDA
Sequence: MANQDQAYLDLLKKIMTEGNDKNDRTGTGTRSLFGAQMRFDLSQGFPILTTKRVPFGLIKSELLWFLRGDTNIRFLLEHKNHIWDEWAFKNWVTSPEYQGPDMTDFGLRSQKDPGFKAVYDEEMQKFCQRILDDEAFAQKYGNLGDVYGAQWRHWGKRDGGFIDQIADVIEQIKTNPDSRRLIVTAWNPEDVPSSALPPCHVLFQFYVADGKLSLQLYQRSGDMFLGVPFNIASYSLLLSLIARETGLEVGEFVHTIGDAHIYKNHFAQVEEQLKRKPFDAPTLWLNPGKKKVADFEMADIKLVNYQHGSTIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOX3_HUMAN
Sequence: MRPVRENSSGARSPRVPADLARSILISLPFPPDSLAHRPPSSAPTESQGLFTVAAPAPGAPSPPATLAHLLPAPAMYSLLETELKNPVGTPTQAAGTGGPAAPGGAGKSSANAAGGANSGGGSSGGASGGGGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPSGLLPPGAAAAAAAAAAAAAAASSPVGVGQRLDTYTHVNGWANGAYSLVQEQLGYAQPPSMSSPPPPPALPPMHRYDMAGLQYSPMMPPGAQSYMNVAAAAAAASGYGGMAPSATAAAAAAYGQQPATAAAAAAAAAAMSLGPMGSVVKSEPSSPPPAIASHSQRACLGDLRDMISMYLPPGGDAADAASPLPGGRLHGVHQHYQGAGTAVNGTVPLTHI
What is the function of this protein?
Transcription factor required during the formation of the hypothalamo-pituitary axis.  May function as a switch in neuronal development.  Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation.  Required also within the pharyngeal epithelia for craniofacial morphogenesis.  Controls a genetic switch in male development.  Is necessary for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity).
What are the official names of this protein?
Transcription factor SOX-3.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNAA_ENTFA
Sequence: MPDVESFWHSLEEAYQAILSAPSFDAWIKTTRPLKLDNNQLWLEVPSAVHRDYWEKNLSAKIVETGFKLTGAEVMPHFVVADEKDAALAQELEEPAEEEVVFSEQSKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHAIGHQMLVNQPDAKVKYVSSETFTNEFINSIQTKTSEQFRKEYRNVDLLLVDDIQFLAEKEATLEEFFHTFNDLYNENKQIVLTSDRPPNDIPKLPERLVSRFAWGLSVDITPPDLETRIAILRKKADAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFATINGEDITTSLAADALKSLKSVGSKNQLSILQIQEEVSKYYHVPLKDLKGKKRVKTIVVPRQISMYLAREMTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLLEKDPAIQKEVSEIKNLLNS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIHC_SALPA
Sequence: MTASLHIILDTDPGIDDAAAIAAALFAPQLDLQLITTVAGNVSVEKTTRNALQLLHFWNSDIPLAQGAATPLLRPLRDAAYVHGESGMEGYDFVDHQRQPLAKPAFISIRDVLMNAPEPMTLVAIGPLTNIALLLMHYPECACNIRRLVLMGGSAGRGNFTPNAEFNIAVDPEAAAHVFRSGIEIVMCGLDVTNQAMLSPDFLNKLPALNRTGKMLHSLFNHYRSGSMRTGVRMHDLCAIAWLVRPELFTLQSCFVAVETQGEYTAGTTVVDIEGRLGQPANAQMALDVDGFRQWVAEVFAYAP
What is the function of this protein?
Hydrolyzes both purine and pyrimidine ribonucleosides with a broad-substrate specificity.
What are the official names of this protein?
Non-specific ribonucleoside hydrolase RihC, Purine/pyrimidine ribonucleoside hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihC subfamily.
Protein: ARAA_ESCF3
Sequence: MTIFDNYEVWFVIGSQHLYGPETLHQVTQHAEHVVNALNTEAKLPCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQFHTQFNAVLPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERIGSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDVNALVDEYESSYTMTPATQIHGEKRQNVLEAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAAEEKPILDVQHLGIGGKDDPARLIFNTQTGPAIVASLIDLGDRYRLLVNCIDTVKTPYSLPKLPVANALWKAQPDLPTASEAWILAGGAHHTVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: MOBA_SHEPC
Sequence: MPLHIDAVILAGGMARRMGGDDKGLVELNGQPMIKHTIDRIKPQVKEILINANRNQTRYAEFGFKVISDEHSGFLGPLAGMLAALGQTKADYLLTVPCDSPQLPMDLVERMLNAIETKGADMAVASNGEQEQPVVLLMKPSLRDSMEAFLKAGDRKILLWYAKQNYAVATFADQPNAFMNINTLEEKQQFALDQT
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCST_HALSA
Sequence: MGLRTSPLHGRHEDRGASFTEFGGWNMPVDFDGIQAEHAAVREAAGIFDVSHMGEIEVSGPDAERLMQRLTTNDVSRLDPGDAQYAAITDDDGIMIDDTVVYRTPADWPGAFLFVPNAGHDAAAFDRWTDHRDAHDLDASVDNVTTDYGMVAVQGPDAPDLVAARAGDGVHDLGRFEAATVGVAGVECLVANTGYTGEAGVEIVFPADGAGAVWDAIANDCQPCGLGARDTLRMEHGFLLSGQDFDPEENPRTPFEAGIGFAVAPESGFVGRDALADTDSPEQQFVGLTLDERGVPRHGYAVTTPAGDEIGTVTSGTMSPTLGEPIGLGYVDSAHAADGTTVAVRIRGTDKQATITTPPFLDQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Probable aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: PAGP_PHOLL
Sequence: MKFDLTAACTLSATLLVSSGTVFATTANTANKSLTTIESHTPISYGNNSSSLWEKFNNNVALTWDAPNNELYLPVITWHNRHTYDKEKTDRYNERPWGFGYGKYRYDEDNDWHSLYAMAFMDSHNRLEPIVGYGFQKMWIPGDLEGFRMGIGFTLSVTARHDYYYVPIPLPLPLFSIEYDRLSFQGTYIPGTYNNGNVLFAWLRWQW
What is the function of this protein?
Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors.
What are the official names of this protein?
Lipid A acyltransferase PagP, Lipid A acylation protein.
What is the protein family that this protein belongs to?
Belongs to the lipid A palmitoyltransferase family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RL6_GLOC7
Sequence: MSRIGKRPITIPNKVTVNIDGSHVAVKGPKGELQRTLPTLVIVEQDEGVLRVVRQDDSRTARQRHGLCRTLVSNMVEGVSKGFEKRLEIQGVGYRAAAQGSKLTLNVGYSKPVEMDMPSGIGVAVEKNTEITITGIDKEIVGNVAAKIRAVRPPEPYKGKGIRYKGEVVRRKAGKTGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: ATPH_HELAN
Sequence: MNPLISAASVIAAGLAVGLASIGPGVGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ARTP_ECOLI
Sequence: MSIQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFDFTKTPSDKAIRDLRRNVGMVFQQYNLWPHLTVQQNLIEAPCRVLGLSKDQALARAEKLLERLRLKPYSDRYPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEITAQIVSIIRELAETNITQVIVTHEVEVARKTASRVVYMENGHIVEQGDASCFTEPQTEAFKNYLSH
What is the function of this protein?
Part of the ABC transporter complex ArtPIQMJ involved in arginine transport.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Arginine transport ATP-binding protein ArtP.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TYSY_XANC5
Sequence: MKPYLELLQHVLEHGAEKSDRTGTGTRSVFGWQMRFDLNDGFPLVTTKKLHLRSIIHELLWFLKGDTNIGYLSDNQVRIWDEWADDNGDLGPVYGKQWRRWTGPDGVEIDQMQWLVDEIKRNPDSRRLVISAWNVGELPQMALMPCHSLFQFYVVNGKLSCQLYQRSGDIFLGVPFNIASYALLTHMVAQATGLGVGDFVHTLGDAHLYSNHFEQAREQLTRTPRALPTLRLNPEVTDLFGFRFEDIAIEGYAPHPAIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MENG_STACT
Sequence: MAKNKAEKEKVHKVFQNISTNYDKLNNIISFEQHKVWRKRVMKSMQVKKGSKALDVCCGTADWTIALSKAVGPSGEVIGLDFSENMLKVGEEKTKNMSNIQLVQGDAMDLPFDDNEFDYVTIGFGLRNIPDYVIALKEMNRVLKPGGMAVCLETSQPTIPVFKQGYQLYFKFVMPIFGKLFAKSKEEYEWLQQSAFNFPDRDELKALFQLAGFKNVEVKSFTGGVAAMHLGYKEKETAKGD
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: GMSS_SHIDS
Sequence: MKKATLVIGVIGADCHAVGNKVLDRVFSNHDFRVINLGVMVSQDEYIDAAIETGADAIVVSSIYGHGDIDCLGMRERCIERGLGDILLYVGGNLVVGKHDFADVETKFKEMGFDRVFAPSHDLEDVCQLMAHDINQRHDVDTRILEEAI
What is the function of this protein?
Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
What are the official names of this protein?
Glutamate mutase sigma subunit, Glutamate mutase S chain, Glutamate mutase small subunit, Methylaspartate mutase.
What is the protein family that this protein belongs to?
Belongs to the methylaspartate mutase GlmS subunit family.
Protein: KA168_BUTPA
Sequence: GLIDVKCYASRECWEPCRKVTGSGQAKCQNNQCRCY
What is the function of this protein?
Poorly competes with (125)I-kaliotoxin binding on rat brain synaptosome (IC(50)>100 nM).  Is a poor Kv1. 3 ligand (PubMed:23523531).  May have as real target KCa1. 1/KCNMA1 channel (By similarity).  Shows weak toxicity on mice (PubMed:23523531).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 16.8, Toxin BoP1.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 16 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SGPL1_HUMAN
Sequence: MPSTDLLMLKAFEPYLEILEVYSTKAKNYVNGHCTKYEPWQLIAWSVVWTLLIVWGYEFVFQPESLWSRFKKKCFKLTRKMPIIGRKIQDKLNKTKDDISKNMSFLKVDKEYVKALPSQGLSSSAVLEKLKEYSSMDAFWQEGRASGTVYSGEEKLTELLVKAYGDFAWSNPLHPDIFPGLRKIEAEIVRIACSLFNGGPDSCGCVTSGGTESILMACKAYRDLAFEKGIKTPEIVAPQSAHAAFNKAASYFGMKIVRVPLTKMMEVDVRAMRRAISRNTAMLVCSTPQFPHGVIDPVPEVAKLAVKYKIPLHVDACLGGFLIVFMEKAGYPLEHPFDFRVKGVTSISADTHKYGYAPKGSSLVLYSDKKYRNYQFFVDTDWQGGIYASPTIAGSRPGGISAACWAALMHFGENGYVEATKQIIKTARFLKSELENIKGIFVFGNPQLSVIALGSRDFDIYRLSNLMTAKGWNLNQLQFPPSIHFCITLLHARKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQTTVDRNMVAELSSVFLDSLYSTDTVTQGSQMNGSPKPH
What is the function of this protein?
Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine.  Elevates stress-induced ceramide production and apoptosis (PubMed:11018465, PubMed:14570870, PubMed:24809814, PubMed:28165339).  Required for global lipid homeostasis in liver and cholesterol homeostasis in fibroblasts.  Involved in the regulation of pro-inflammatory response and neutrophil trafficking.  Modulates neuronal autophagy via phosphoethanolamine production which regulates accumulation of aggregate-prone proteins such as APP (By similarity).  Seems to play a role in establishing neuronal contact sites and axonal maintenance (By similarity).
What are the official names of this protein?
Sphingosine-1-phosphate lyase 1, S1PL, SP-lyase 1, SPL 1, hSPL, Sphingosine-1-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family. Sphingosine-1-phosphate lyase subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type III membrane protein; Cytoplasmic side.
Protein: MNMA_CORJK
Sequence: MRVVAAMSGGVDSAVAASRALEAGHEVIGVHLALSQSPEAVRAGSRGCCSLEDSADARRVADKLGIPFYVWDFSDRFKADVIDDFVDSYAIGETPNPCLRCNEKIKFEALLDRSIALGFDAVVTGHYARLHDGVMRRGVDANKDQSYVLGVLTDEQLAHCMFPVGDTIKPEIREEAKDHGFGVASKPDSHDICFIPDGQTQAFLGKKIGLRPGLMKDQDGSTVAEHDGVYGFTIGQRKGLGLPREGLDGKPRYVTDIDAATGTVTIGQRDDLRVGGITADRLKRLDPAVHGREFECEVQVRAHGGVVPATARLVDDPERTTPAGRVKKEDESPWRLELDLHEPLQGVARGQAAVVYQPDADGDILLGSGTIRATAPWSDAGAAGTAGERATPAEA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_STRA3
Sequence: MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYTTGEWLNRKFSLIDTGGIDDVDAPFMEQIKHQADIAMTEADVIVFVVSGKEGVTDADEYVSLILYKTNKPVILAVNKVDNPEMRNDIYDFYSLGLGDPYPLSSVHGIGTGDILDAIVENLPVEEENENPDIIRFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTNFVDSQGQEYTMIDTAGMRKSGKVYENTEKYSVMRSMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHEAGKGIIIVVNKWDTIEKDSHTVSQWEADIRDNFQFLSYAPIIFVSAETKQRLHKLPDMIKRISESQNKRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVAVKPPTFVVFVNEEELMHFSYLRFLENQIREAFVFEGTPINLIARKRK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: TATB_BORPA
Sequence: MFDVSFTELMVIGVIALVVIGPERLPKVARTIGHLLGRAQRYVNDVKSDIRREIELDELRKFKDEMDETARSMQTSLRETEDTLRDSTQALRAELDDTARDASKAVNGADAPAEPAPAVASDTDTDTDTRSIAPPAAATPADKTPPTGSAT
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SYR_BURMA
Sequence: MLPAQKHTLETLLENSVKQVVQASKGDADAAFVLPAIALERPKVAAHGDVACNVALQLAKPLGANPRQLAEQIVAALTAQPEAAGLVDAAEIAGPGFINLRLTPASKQAVIGAVLAQGRAFGASERDHDKRVLLEFVSANPTGPLHVGHGRQAALGDALANVLASQGYAVHREFYYNDAGVQIGNLAISTQARARGLKPGDAGWPEAAYNGEYIADIARDYLNGETVAASDGEPVTGKRDVEDLEAIRKFAVTYLRREQDMDLKAFGVKFDQYYLESSLYTEGRVEKTVDALIAAGMTYEQEGALWLRTTDEGDDKDRVMRKTDGTYTYFVPDVAYHVTKWERGFTKVINIQGSDHHGTIARVRAGLQGLHIGIPKGYPDYVLHKMVTVMRDGQEVKISKRAGSYVTVRDLIEWSGGATPGSEGSPELLDEATITRGRDAVRFFLISRKADTEFVFDIDLALKQNDENPVYYVQYAHARICSVINEWKSRYGATDALLPGADLSPLDSKQAMALMQKLAEYPDVLAHAAGELAPHAVAFYLRELASEFHSFYNAERVLVDEQAPRTARVALLAATRQVLENGLAMLGVSAPSKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_BIFLD
Sequence: MNFFQAIILGIVQALTEYLPVSSSAHIRIFGDLMLGSDPGAAFTAIIQIGTELAVILYFRHDIINILTHWFSCLFGKNGKDWKARMGRGDNYATLGWNIIVGSIPIIILGFTLQNVIETSLRNLWITVTVLLVFGILLWMVDAKARQNKTMNDMTYRDAFLFGLGQSMALIPGVSRSGGTITVGRALGYTREAAVRLSFLMAIPAVFGSGLLEAIKAVKNYKTDAMFPGWGPTLVAMVISFVLGYIVIIGFLKFVSNFSYKAFAIYRIGLAVVVALLLIVGVLPAIDPSVVAAA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PTAR1_DANRE
Sequence: MAESEEEVDVLVQRVVKDITNAFKRNPNIDEIGLIPCPEARYNRSPIVLVENKLGVESWCVKFLLPYVHNKLLLYRQRKQWLDREALVDITSTLLLLNPDFTTAWNVRKELLQCGVLNPEKDLYLGKLALSKHPKSPETWIHRRWVLQRLQKECSPSGQELKDSAESRRQCERLQRALQEEMRVCAEAAGRYPSNYNAWSHRIWVLQNMAKGNLKVLHDELSSTRLWVSMHVSDHSGFHYRQHLLKALAKELSPAAEKDVHTSQQPNGENTATASDDNHHKDVMPRLFHEEIQLCTDLIESYPGHETLWCHRRHVFYLWHQWRREHMQGAGSQSPALTHTDVLLSKELCDNNSISQAMDIDCVLDGSKHGSYTQDTKRLKRGPLLLQPGFPSEHTFISRILTGCRNPEQSRFAIAYRKWLDSVIGQ
What are the official names of this protein?
Protein prenyltransferase alpha subunit repeat-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein prenyltransferase subunit alpha family.
Protein: CATIP_XENLA
Sequence: MEPENAQGKSPAENEQEVVPDVASAMSASSEALEFLCSVGLEELNLCLFTDSLATVSVSGVELGNFAVSVQPAYYQLDGLEEEKCFLVHAASQGTIDGVPCGTSIIGHISYKLETLEQHVHEYVKLKGHSLDKKTQIVRQGDKLVINRIITEGEKLHRETSSHSTSLLSGLISEAANLLIMRILARRKIKDPLKFLAFDEEGNLCTSTYAPLGSQAQVIGKEMVDVFGIERTIHSPEVPTTWQCFFLSDGHLASHVQIGSPVTIKLNEMPVLSEPDEKDPKPVFEKKPLAWQEDLQLHSEFLDRKEELISDHETYLRRHPEVKVLLADFMQFLLLRKPDDIMDFAAEYFKPFSSTQEPNDPFVSSHHASPFRNVSH
What is the function of this protein?
Plays a role in primary ciliogenesis by modulating actin polymerization.
What are the official names of this protein?
Ciliogenesis-associated TTC17-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the CATIP family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell membrane. Cytoplasm, cytoskeleton.
Protein: RU1C_AEDAE
Sequence: MPKYYCDYCDTYLTHDSPSVRKTHCTGRKHKDNVKFYYQKWMEEQAQHLIDATTAAFKAGKIAQNPFSAGPPKPNVAIPPPSMGMPARPGMIPGMPAGAPPLLMGPGPMGMRPPMMMPMGMPPMGMGMRPPMMNGPPPQMNQKVYHNTDRRYHR
What is the function of this protein?
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome.  U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing.  The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA.  Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
What are the official names of this protein?
U1 small nuclear ribonucleoprotein C, U1 snRNP C, U1-C, U1C.
What is the protein family that this protein belongs to?
Belongs to the U1 small nuclear ribonucleoprotein C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL2_STRT1
Sequence: MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKNKAGRNNNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKAYIIAPKGLEVGQRIVSGPDADIKVGNALPLANIPVGTVIHNIELKPGKGAELVRAAGASAQVLGQEGKYVLVRLQSGEVRMILGTCRATIGTVGNEQQSLINLGKAGRNRWKGVRPTVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNEK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RS4_FINM2
Sequence: MARMMGPRFKQSRRLGLNVCGHPKANKRMGKGLGRNDKKLTEYGMQLLEKQRLRAYYGVNEKQMHKYFEKALNNKEGLTTGDVMVRQLETRLDNLVLRASFASSIRQARQMVSHGLIRVNGKKVDIPSFQVAEGSVIELKEKSRSNELFKENYETNFAQSLPYIDKEENFKVTLTRLPERQEIPIEITDSLIVELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: VH22_RFVKA
Sequence: MTITMIDMEVYLVDENLSIKNAGLSHGYSCGCILKLDITSPKKVKMLVITKVTSFQAIQELKPLNAKLNGSDLDTELVKCYNTTTDLTVYKTSAYHRDMPDKEYCVTRIYSVMANIDSKSTIEFYGTTSDEFLSAYPVIYINPEEKYYKVKNKGRLQMRVITPILNSDKLQFMAKGDMYAGVGDDPSIVDSSDSDEETDYDY
What is the function of this protein?
Plays a role for multiplication of the virus in different cell types.
What are the official names of this protein?
Probable host range protein 2-2.
What is the protein family that this protein belongs to?
Belongs to the poxviridae C7 protein family.
Protein: YNEG_ECOLI
Sequence: MQSLDPLFARLSRSKFRSRFRLGMKERQYCLEKGAPVIEQHAADFVAKRLAPALPANDGKQTPMRGHPVFIAQHATATCCRGCLAKWHNIPQGVSLSEEQQRYIVAVIYHWLVVQMNQP
What are the official names of this protein?
Uncharacterized protein YneG.