PharMolix/UniProtQA huggingface dataset:
Protein: COX2_LYCVE
Sequence: MAYPFQLGLQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETVWTILPAIILILIALPSLRILYMMDEINNPSLTVKTMGHQWYWSYEYTDYEDLNFDSYMIPTQELKPGELRLLEVDNRVVLPMEMTVRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQTTLMAMRPGLYYGQCSEICGSNHSFMPIVLEMVPLSYFETWSAVMV
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYL_MARN8
Sequence: MDEQYNPREVEQTARTFWETNETFKVKEEPGKPKYYCLSMFPYPSGKLHMGHVRNYTIGDVISRYQRMQGKNVMQPMGWDAFGLPAENAAIANKSAPAKWTRSNIDYMKNQLKQLGFGYDWSRELATCDPEYYRWEQWFFARLYEKGLVYKKMSTVNWDPVDQTVLANEQVVDGRGWRSGALVEQKKIPQWFIRITDYAEELLNDLEDMEGWPEQVKTMQRNWIGKSVGTELTFPLKEQEGGLTVYTTRPDTLMGVSYMAVAAEHPLAKAAAERHRDVAEFVDQCRNSKVAEAELATMEKKGIDTGFKAIHPLTQEEIPVWVANFVLMDYGTGALMAVPGHDERDHEFAVKYKLPIKQVIAPNDSRDIDIQEQAFTEKGVLVSSGKYSGLTSEEAFEEIADYLEAQGIGKRTVNYRLRDWGVSRQRYWGAPIPMMTLEDGTEMPVPDDQLPVRLPEDVEMDGVQSPIKADPEWCKTEYNGQPATLETDTFDTFMESSWYYARFCSPNYDKGMLDPAAANYWLPVDQYIGGIEHAILHLLYARFFHKLLRDVGLVNSSEPFKRLLTQGMVLAETYYRNEANGGKTWYNPADVTVERDGKGQVVRAVLKSDGEPVEIGGVTKMSKSKNNGIDPQAIIDQHGADTVRLFMMFAAPPEQSLEWSDSGVEGAHRFLKRLWRMVNEHTAGGDAPAVDPANLNGAQKDLRRKTHETIAKVSDDISRRLTFNTAIAAVMELLNEVGRLSDDEPQSRAVRQEALDTAVLVLSPIVPHICHNLWQALGHSDAVVDASWPVADESAMVRSEIEVVLQVNGKVRAKENVPADIGKADLEKLALENENVMRFTDGKTVRKVIVVPGKLVNVVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUFS_HALVD
Sequence: MRVQESYPVDVDAIRADFPILERKVGGDISTPGEHDDDTTPLVYLDNAATSHTPEQVVDAIVDYYHGYNSNVHRGIHHLSQEASVAYEDAHDRVAEFIGASGGREEVVFTKNTTESMNLVAYAWGLDELGPGDSVVMTEMEHHASLVTWQQIAKKTGAEVRYIRVDDDGRLDMEHAKELIDDSTKMVSVVHVSNTLGTVNPVSELADMAHEVGSYIFVDGAQSVPTRPVDVEDIDADFFAFSGHKMCGPTGIGALYGKRDILDEMGPYLYGGEMIRSVTYEDSTWEDLPWKFEAGTPPIAQGVGFAAAVDYLDDIGMENVQAHEELLAEYAYDRLTEFDDIEIYGPPGDDRGGLVSFNLDSVHAHDLSSILNEQGVAIRAGDHCTQPLHDKLGVAASTRASFYIYNAREEVDKLVDAIDAARELFA
What is the function of this protein?
Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Able to reassemble a removed [2Fe-2S] cluster of an apo-ferredoxin.  Shows a selenocysteine lyase activity approximately 280-fold higher than its cysteine desulfurase activity.
What are the official names of this protein?
Cysteine desulfurase, Selenocysteine lyase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
Protein: SYYC_XENTR
Sequence: MGDGLTPEGKAQLITRNLQEVLGEDKMKEILKERPLRIYWGTATTGKPHVAYFVPMSKIADFLKAGCEVTILFADLHAYLDNMKAPWDLLELRTRYYEQVIQAMLQSIGVPLERLRFIRGTEFQLSKEYTLDVYRLSSVVTQHDAKKAGAEVVKQVEHPLLSGLLYPGLQALDEEYLKVDAQFGGVDQRKIFTFAEKYLPALGYAKRIHLMNPMVPGLTGAKMSSSEEESKIDLLDSPADVKKKLKKAFCEPGNIENNGVLSFVRHVLFPLKSEFVVLRDEKFGGNKTYTDFETLEKDFTEQLVHPGDLKASVEKALNKLLDPIREKFNSPEMKKLSNDAYPGASKQKTVPKGSTKNSGPEEIDPSLLDLRVGKILSVRQHPDADSLYVESVDVGEENPRCVVSGLVQYVPSDQLLGRSVVLLCNLKPQKMRGIESQGMLLCASTEGEQKQVEPLDPPTGSAPGERIYIEGYENGEPEGELKPKKKVFEKLQVDFRISDDLCAQWKGKNFLTKLGSVTCKTLRGGSIS
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, cytoplasmic, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINC_SODGM
Sequence: MSQTPIELKGSNFTLSVIHVHDAQPEEIRRAIEEKVEKAPGFLKNAPVVINVAGLGRDTSWEALSQAVLATGLHIVGVSGCSDSKLKQAIVRSGLPLLTEGKAPKRSVDATPALAAVKTRLINTPVRSGQQIYARSSNLIVTSSVSAGAELIADGNIHIYGMMRGRALAGASGDGECQIFCTHLSPELISIAGQYWLSDQIPAALLGKAARLCLQDGTLTIHPLI
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: MIAA_SHEB5
Sequence: MGPTASGKTALALELAEKHNCEIISVDSALIYRGMDIGSAKPSVDELARGPHRLIDIRDPRESYSAADFRADAIAEIEQIVSMGKTPVLVGGTMMYFKALLEGLSPLPSADEAIRAEIQAEADEKGWEALHDQLRDIDPVSAERIHPNDPQRLSRALEVYRISGKSMTELTQTKSAPLPYDVVQFAIAPRERKVLHDLIAQRFAIMLKQGFLEEVTELKARGDLHLDLPSMRCVGYRQCWQYLDGEFDYDTMVEKAVAATRQLAKRQLTWLRSWPELNWLESGAEGNLVTLMRQCR
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: KTHY_METM7
Sequence: MNKFIVFEGIDGCGKTTQAKLIAEKLNAKFTFEPTDGKIGKSIREILSGSKCQKETLALLFAADRVEHVSKIEEDLKKSHVVSDRYVYSSIVYQMSQGIPKDFIYTINDYAKTPDLVVLLDVDLNEALKRMESREKEIFEKIEIQKKIKEGYYSLINSENEKFMPKYGFIIIDTTSKSITQVFDEILNAIIDKIPDIIQ
What are the official names of this protein?
Probable thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: TRPC_FRAAA
Sequence: MSVLAEILDGVRADLAAREQQTPLADLKQRVERVPDPRDALTVFRNSPVSVIAEVKRSSPSKGKLAAIADPAALALDYEAGGAAAISVLTEGRRFGGSLADLDAVRRAVDVPLLRKDFIVSPYQVFEARAHGADLVLLIVAALDQPRLVGLRERIESLGMTALVEVHDEAELGRALDADARLIGINARDLRTLEVDRATFARLAPMVPPGVITVAESGVRGPHDLLAYAAAGADAVLVGEAAVTGDPRQTVADLVAAGAHPAARVGR
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: MGST3_HUMAN
Sequence: MAVLSKEYGFVLLTGAASFIMVAHLAINVSKARKKYKVEYPIMYSTDPENGHIFNCIQRAHQNTLEVYPPFLFFLAVGGVYHPRIASGLGLAWIVGRVLYAYGYYTGEPSKRSRGALGSIALLGLVGTTVCSAFQHLGWVKSGLGSGPKCCH
What is the function of this protein?
Catalyzes oxydation of hydroxy-fatty acids (PubMed:9278457).  Also catalyzes the conjugation of a reduced glutathione to leukotriene A4 in vitro (PubMed:9278457).  May participate in the lipid metabolism (PubMed:9278457).
What are the official names of this protein?
Microsomal glutathione S-transferase 3, Microsomal GST-3, Glutathione peroxidase MGST3, LTC4 synthase MGST3, Microsomal glutathione S-transferase III, Microsomal GST-III.
What is the protein family that this protein belongs to?
Belongs to the MAPEG family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein. Microsome membrane; Lipid-anchor. Membrane.
Protein: RL27_NOCFA
Sequence: MAHKKGASSSRNGRDSNAQRLGVKRFGGQTVKAGEILVRQRGTHFHPGVNVGRGGDDTLFALAAGAVQFGTKRGRKTVNIVAPAPVQA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: VSM6_TRYBB
Sequence: MAVHRALAAYAISLYVLLPRKSGATDKGAIKFETWEPLCLLTQDFGNLYNRAHKLNLDIDTYVTAAQADQLRLQILLSRASSKIEAAAAAAATAAIAADLAGKAKHVASCKLAATTLTATTGYLHGRIAEFLEVMTAHRGTTNKYGCLSKSRSDNSNSITDSVANLKDKCKLTVQQISPDNKATEQITKAGFTKLTATGGLTSSDLGGSGQAVCMILSTTASEVVNNGNLDEPVPYAGGYLRRKHDLTSDGNDNLATITDSASAPATRAKTDPYLQIWRAFKNLEDCESTFTSGYSRPSPETLKAADETKTAIKNYVVQKEGKYDQATDKEDDYKNLDKIFKDGKDFYPQKLWDAMDKKDLLKDATQTNEIKKLADITDRSELNKVLLYYTRQKEQTLTKELKEAQEKATQANQNDAAAKAAEDSCNKLVGGEKCNADKKCSYETETDGTKKCKFNATKAEKSGAPVTQAQTVGETEATPEKCKGKDAKTCGTTQGCKWEGETCKDSSILVTKKFALTVVSAAFVALLF
What is the function of this protein?
VSG forms a coat on the surface of the parasite.  The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.
What are the official names of this protein?
Variant surface glycoprotein MITAT 1.6, VSG.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Note=A soluble form is released from ruptured cells by the action of a PI-PLC.
Protein: ARLY_CUTAK
Sequence: MALWGGRFSGGPSEALAALSVSTQFDWRLARHDIAGSSAHAGVLHAAGLLDDDQYEGMMKALNALEEDVVSGRFVAQPEDEDVHTALERGLMERAGKDLGGRLRAGRSRNDQIIALLRRYLREEARSLAGELLGLAHVLSRQAEDVGDAVIAGRTHMQHAQPVLLAHQLLAHAWPLLRDVQRFRDLDARLDCSPYGSGALAGSSLGLDPEAVARDLGFSSSVPNSIDGTAARDVVAEFAFVAAQVGVDLSRLSEEIIIWNTREFGYVTLDDSFSTGSSIMPQKKNPDIAELARGKAGRLIGDLAGLMASLKGLPLAYARDLQEDKEPVFDQIDQLHLLLPAITGMVDTAVFNTDRMAEMAGQGFSLATDVAEWLVRQGVPFRVAHELSGACVRGAESQNKELADLTDQELIAIDPRLTPQVREVMTVQGSVRSRAGRGGTAPERVAEQITELREAIAGLRSFGEAETR
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLX1_MONBE
Sequence: MAGGYIARVNMKGHYLSWSSDNTYPWQNIQPTQNTKLLGLQDIGFTTDPVRRLRQHNSEIGGGAVRTTRAKGSWDMAAIVYGFPNKVAALRFEWAWQHPLKSRRLRDAVRSDLPASRAAQMQLTAKLHTLAAMLYTVPWSDQPLTLCWLQPDIADKWSNIWQRHCQCQSALPPFLTTRSGNLQDPLFQLNNAAAAASTIQRAALAADHHAWRLAAAAQAQAPDFFTGLGRLDLAAPSVEESGAGPHPSSCSVPPSTGSSAAPTPGALAPQPTKQNKFGVDPRLDSDDRDDNHQFESPDNHEAAAVNVDVVDDSADDGTTDGNEDGPDDVAPHQEVTARHVHGAIGETCGHCHQSVYQELCIVCLNATCTYRAHLLCAAQAAVHPLGQSSPSETRLVPLRHSCPRCAHQAHWASWIAEVTL
What is the function of this protein?
Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit SLX1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SLX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSBA_SELUN
Sequence: MTATLERRENASLWGNFCDWITSTENRLYIGWFGVLMIPTLLTATSVFITAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASIDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANAGYRFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAASIEAPSLNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL17_RUMCH
Sequence: MPGQRKLGRATDQRKAILKNLTTALFVSGRIETTEARAKEVKNIAEKLITLAIKEADNFTSKQVKVSAAKVDSKGKKLTDTKTSKNGKKYFVVEREQKTDMVSVDNASRLHARRLIMNWVYRPTTADGKNINITDKLFDEIAPKYKDKKGGYTRIYKLGPRRGDAAEMVILELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: PUR4_NEIMB
Sequence: MSVVLPLRGVTALSDFRVEKLLQKAAALGLPEVKLSSEFWYFVGSEKALDAATVEKLQALLAAQSVEQTPKAREGLHLFLVTPRLGTISPWASKATNIAENCGLAGIERIERGMAVWLEGRLNDEQKQQWAALLHDRMTESVLPDFQTASKLFHHLESETFSGVDVLGGGKEALVKANTEMGLALSADEIDYLVENYQALQRNPSDVELMMFAQANSEHCRHKIFNADFILNGEKQPKSLFGMIRDTHNAHPEGTVVAYKDNSSVIEGAKIERFYPNAAENQGYRFHEEDTHIIMKVETHNHPTAIAPFAGAATGAGGEIRDEGATGKGSRPKAGLTGFTVSNLNIPDLKQPWEQDYGKPEHISSPLDIMIEGPIGGAAFNNEFGRPNLLGYFRTFEEKFDGQVRGYHKPIMIAGGLGSIQAQQTHKDEIPEGALLIQLGGPGMLIGLGGGAASSMDTGTNDASLDFNSVQRGNPEIERRAQEVIDRCWQLGGKNPIISIHDVGAGGLSNAFPELVNDARRGAVFKLREVPLEEHGLNPLQIWCNESQERYVLSILEKDLDAFRAICERERCPFAVVGTATDDGHLKVRDDLFANNPVDLPLNVLLGKLPKTTRTDKTVAPSKKPFHAGDIDITEAAYRVLRLPAVAAKNFLITIGDRSVGGLTHRDQMVGKYQTPVADCAVTMMGFNTYRGEAMSMGEKPTVALFDAPASGRMCVGEAITNIAAVNIGDIGNIKLSANWMAACGNEGEDEKLYRTVEAVSKACQALDLSIPVGKDSLSMKTVWQDGEEKKSVVSPLSLIISAFAPVKDVRKTVTPELKNVEDSVLLFVDLGFGKARMGGSAFGQVYNNMSGDAPDLDDTGRLKAFYSVIQQLVAENKLLAYHDRSDGGLFAVLVEMAFAGRCGLDIDLNLLLAQTFITNHTALSQSLRTEEVKALAEWQETIARTLFNEELGAVIQVRKQDVADIINLFYQQQLHHNVFEIGTLTDENTLIIRDGQTHLISDNLIKLQQTWQETSHQIQRLRDNPACADSEFALIGDNERSALFADVKFDVNEDIAAPFINSGAKPKIAILREQGVNGQIEMAAAFTRAGFDAYDVHMSDLMAGRIHLADFKMLAACGGFSYGDVLGAGEGWAKSILFHPALRDQFAAFFADPDTLTLGVCNGCQMVSNLAEIIPGTAGWPKFKRNLSEQFEARLSMVHVPKSASLILNEMQGSSLPVVVSHGEGRADFALHGGNISADLGIALQYIDGQNQVTQTYPLNPNGSPQGIAGVTNADGRITIMMPHPERVYRAAQMSWKPEGWTELSGWYRLFAGARKALG
What is the function of this protein?
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase, FGAM synthase, FGAMS, Formylglycinamide ribonucleotide amidotransferase, FGAR amidotransferase, FGAR-AT.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_ACHLI
Sequence: MNGIFLVNKKAGLTSHDIVYQIRKKFNIKKVGHTGTLDPFATGLLIILVGKATKLAFLFDELDKQYDGTIVLGKSYDTDDTTGEVINEAPVSFTEDDLKAILNRIVPTYKQIPPSYSAIKKAGVKAYEAARSGKPLDLPAREVSIYNFTYQINKQTIDFSTHVSKGTYIRSIARDIGLGLNTFGALSVLNRTNIDAYSQNMSKTVEDTELPDLIDHALLFEGVKKIVLNDYLIKLVKNGVVLDERQTTLNEPFIVQDEMGNYIAYYVPDNQQYKLKYLF
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: SRP54_PYRFU
Sequence: MVLDNLGKALANTLKKIARASSVDEALIKELVRDIQRALIQADVNVRLVLQLTREIQRRALEEKPPAGISKKEHIIKIVYEELTKFLGTEAKPIEIKEKPTILLMVGIQGSGKTTTVAKLARYFQKRGYKVGVVCSDTWRPGAYHQLRQLLDRYHIEVFGNPQEKDAIKLAKEGVDYFKSKGVDIIIVDTAGRHKEDKALIEEMKQISNVIHPHEVILVIDGTIGQQAYNQALAFKEATPIGSIIVTKLDGSAKGGGALSAVAATGAPIKFIGTGEKIDDIEPFDPPRFVSRLLGLGDIQGLLEKFKELEKEVEIKEEDIERFLRGKFTLKDMYAQLEAMRKMGPLKQILRMIPGLGYSLPDDVISIGEERLKKFKVIMDSMTEEELLNPEIINYSRIKRIARGSGTSTKDVKELLDQYRQMKKLFKSMNKRQLSRLARRFGM
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes.  The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
What are the official names of this protein?
Signal recognition particle 54 kDa protein, SRP54.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Protein: RUTF_ECO5E
Sequence: MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQNGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHATPYGLVWFDRSYHALMRPAC
What is the function of this protein?
Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.
What are the official names of this protein?
FMN reductase (NADH) RutF, FMN reductase, NADH-flavin reductase RutF, NADH:flavin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
Protein: YBEY_STRT2
Sequence: MYVEMIDETGQVSEEIKKQTLELLDFAAQKLGKKDKEMAVTFVTNERSHELNLEYRDTDRPTDVISLEYKPELDITFDEEDLAENPELAEMMGEFDSYIGELFISIDKAREQAEEYGHSYEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAYGLTRQ
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOK_HAMD5
Sequence: MIPMQHGLILAAILFTLGLTGLLIRRNLIFMLISLEVMINSAALAWVVAGSHWGHPDGQIFYLLAITLAAAEASIGLALLLQLYRRHHTLNIDILSEMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DACT1_XENTR
Sequence: MKPIPATPDHLGQHQESPRRKDKGEAESERQRTRERLEATLAGLAELGYLRHRQELLVKSALTPGAPTHGDTATRAGDTPRSLEEKFLEDNILLLKKQLNCLRKRDAGLLSQLHELDKQINDLKIDVEKTEEHLETDSRPSSGFYELSDGTSGSLSNSSNSVFSECLSSCHSSTCFCNPLETSLNLTDGQAKSADDFLEWLDYRDSQHETGTVRRSFSAPHSNSVDVAADVHPKYQCDLVSKNGNDIYRYPSPLHAVAVQSPMFLLSVMGNIKAEEPEEEIGPNDNDDCIVPELDHLKDEDSFLHQSSLCSLPLSSGKKMDGYILSIIQKKAHPVRTNKPRTSVNADPGKGILRHGSICVKQTGGVSQSSTVNLKNSKQTCLHSTGMISVDNSTYPSLKQCSKESLSEQLESKRMPSISTYPSCNVNELQSQNNSRNTVKSVCQGLARGSVAMTSNVQKENVTPNAPTNLSNASSSACNGSPRESTQMSALLPQEIKVVPPVKKISPKNTLLSYHASSSFDERPPLDFKSEGSSSQSLDEGLLVNAHYIPAQQQGVKLHKNIKNVKIVKSSTLKHRANVQYVAENGSQTLKEKSKAVGKKCRFPEDLDTNKKVKKSTPRTKKTSHPNFEPAVVGRNPVAVRSGIKSHGQPKDVVLAKPKHKRGDYRRWKSSAEISYEEALRRARRRAQREMMGVYAQVPFPYASPYAYIASDSEYSAECESLFHSTVVDTSEDEQSNYTTNCFGDSESSLSEVEFVGESTTSSDTDESGGLIWSQFVHTLPMQATATAELQTTAKAFVKIKASHNLKKKILRFRSGSLKLMTTV
What is the function of this protein?
Involved in regulation of intracellular signaling pathways during development.  Specifically thought to play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH (Dishevelled) family proteins.  Binds to dvl2 and regulates the degradation of ctnnb1/beta-catenin, thereby modulating the transcriptional activation of target genes of the Wnt signaling pathway.  May also bind to and directly stimulate the activity of tcf7l1 (By similarity).
What are the official names of this protein?
Dapper 1.
What is the protein family that this protein belongs to?
Belongs to the dapper family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CHIC_POPTR
Sequence: MSVWAFFAFFSLFLSLSVRGSAEQCGRQAGDALCPGGLCCSFYGWCGTTVDYCGDGCQSQCDGGDGCDGGGGGGGDGDDGYLSDIIPKSTFDALLKFRNDPRCHAVGFYTYDAFISAAKEF
What is the function of this protein?
Defense against chitin-containing fungal pathogens.
What are the official names of this protein?
Acidic endochitinase WIN6.2C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family. Chitinase class I subfamily.
Protein: AR19A_XENLA
Sequence: MSGENQETKAQEESSALEQKEIDDKVVSPEKSEEIKLKARYPNLGPKPGGSDFLRKRLQKGQKYFDSGDYNMAKAKMKNKQLPTAASDKTEVTGDHIPTPQDLPQRKPSLVASKLAG
What is the function of this protein?
Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.  When phosphorylated at Ser-67 during mitosis, specifically interacts with ppp2r2d (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase.
What are the official names of this protein?
cAMP-regulated phosphoprotein 19-A, ARPP-19-A.
What is the protein family that this protein belongs to?
Belongs to the endosulfine family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAR1_KLULA
Sequence: MAGWDLFGWFRDILSSLGLWNKHGKLLFLGLDNAGKTTLLHMLKNDRLATLQPTWHPTSEELAIGNIKFTTFDLGGHLQARRLWKDYFPEVNGIVFLVDAADPERFNEARIELDALFQIKELDNVPFAVLGNKIDSPSAVSETELRAALGLMNTTGYTKIEGQRPIELFMCSVVMKSGYSEAFKWLSEYI
What is the function of this protein?
Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.  SAR1 controls the coat assembly in a stepwise manner.  Activated SAR1-GTP binds to membranes first and recruits the SEC23/24 complex.  These SEC23/24-SAR1 prebudding intermediates are then collected by the SEC13/31 complex as subunits polymerize to form coated transport vesicles.  Conversion to SAR1-GDP triggers coat release and recycles COPII subunits (By similarity).
What are the official names of this protein?
Small COPII coat GTPase SAR1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. SAR1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AAT_STRGR
Sequence: MSAATSPSERRVSARIGAISESATLAVDAKAKALKAAGRPVIGFGAGEPDFPTPDYIVDAAVEACRNPKYHRYTPQRAPELKAAIAEKTLRDSGYEVDAGQILVTNGGKQAIYEAFAAILDPGDEVIVPAPYWTTYPESIRLAGGVPVEVVADETTGYRVSVEQLEAARTEKTKVVLFVSPSNPTGAVYSEADAEAIGRWAVEHGLWVMTDEI
What are the official names of this protein?
Probable aspartate aminotransferase, AspAT, Transaminase A.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.