PharMolix/UniProtQA huggingface dataset:
Protein: NUOK1_KORVE
Sequence: MAEIGTMHYLVVAAMLFIIGTVGVVTRRNVVVILMSIELILNAVNLNLVAFSRLYGLHGQVFSIFVMVDAAAEAAVGLGIVIAFFRNKETVNVDEVDLLKW
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K 1, NADH dehydrogenase I subunit K 1, NDH-1 subunit K 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RSMH_CLOP1
Sequence: MEFKHVSVLLDECINALNIKEDGIYVDCTLGGAGHSSEIVKRLSSDGRLIGFDQDKDALKAAGERLKDYKNVTYVHSNFYAIYDVLTDLGIDGVDGILMDLGVSSYQLDNGERGFSYMQDAPLDMRMNRENEFSAYEIVNTYSEEELYRIIKEYGEEKFAKRIASFIVKNREEKNIETTLELVEIIKAAIPAKARREGPHPAKRTFQAIRIEVNKELEIISKTILDGVKKLNKGGRMAIITFHSLEDRIVKNTFKELANPCTCPSEFPVCVCNRKPEVKLISRKPIEASKEELEFNPRSRSAKLRIIEKL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NBPF9_HUMAN
Sequence: MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVAEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQIEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEENQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ
What are the official names of this protein?
Neuroblastoma breakpoint family member 9.
What is the protein family that this protein belongs to?
Belongs to the NBPF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_POLNA
Sequence: MAKQALLQRELKRDKLVAKFAKKHAEFKAIANDFKRTDDERALARLELQKLPRNANPTRQRNRCAITGRPRGTFRQFGLARAKIRELAFAGDIPGITKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: YK17_SCHPO
Sequence: MGAVLSIPLALASSLSGVVGIASSFLVTSVLSLTNSIQSNVGAVISYAVLYFVNSLLSWCMLSSWFNSKLSKLSAGYLQFDCQNDGKCYSVIAVHRLSFTLVMFHLFLAFILSLCNTRSRVAIKIQNGLWPFKIVLWFVLGIFSFFIPTKFLSFWGNIISVMGSALFIVYGLMLLVDFAHTWAERCVDRVLTSDSSSSKFYLIGSTVGMYVVGLVLTILTYVFFCASSCSFNQAINTINLLLCIAVSCLSVHPTIQEYNPRSGLAQSSMVMCYTCYLILSALANRPDEGQCNPWGNSASGTREFSKVIGAAFTFFTILYSAVRAASSRESDDSYSYLYADSHDMGVSTPLEDGSSEEDKHQSDYNFIWFHIVFVLAAFYTASLLTNWNTTSVYENQKNDVFVRIGFSYAAVWVKIITSWVCHGLYVWSCLAPVFFPYRFMI
What are the official names of this protein?
Membrane protein PB1A10.07c.
What is the protein family that this protein belongs to?
Belongs to the TDE1 family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: FTHS_CLOTE
Sequence: MEKVLTDIEIAQKAQMKPIGEIAEKYGILEDELELYGKYKAKLSLDIFDRLKDEKDGKLVLVTAISPTPAGEGKSTTSIGLGQALNKIGKKTFIALREPSLGPVFGVKGGAAGGGYAQVVPMEDINLHFTGDMHAIGITNNLLSAAIDNHIHQGNALKIDSREIVWKRVVDMNDRALRNVVVGMGGKACGFTRQDGFMITVASEVMAILCLAKDLMDLKERLGNIIVAYSLEGKPVTAGDLKVNGAMAMLLKDAIKPNIVQTLENTPALIHGGPFANIAHGCNSLIATRLGLKLGDILVTEAGFGADLGAEKFLDIKCRYGGLKPDAVVIVATIRALKMHGGVKKTELSGENLEALDKGFANLQKHITNMKNFGLPVMVAVNRFITDSEAEIDLLIKKCKEIGVEVSLNEVWAKGGEGGIEMAEKLVKILETEKPNYKPLYDVEDSIPEKLNKIVKELYGGEGVVIESSAMKQIKKLEEIGLDKLPICMAKTQFSFSDDATLMGAPKGFNITIKNVRVSAGAGFIVCETGNIMVMPGLPKVPAAEKMDVDENGNISGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: KDUI_ECO57
Sequence: MDVRQSIHSAHAKTLETQGLRNEFLVEKVFVADEYTMVYSHIDRIIIGGIMPVTKTVSVGGEVGKQLGVSYFLERRELGVINIGGAGTITVDGQCYEIGHRDALYVGKGAKEVVFASIDTGTPAKFYYNCAPAHTTYPTKKVTPDEVSPVTLGDNLTSNRRTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYFYFNMDDDACVFHMMGQPQETRHIVMHNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVKDLR
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase, DKI isomerase.
What is the protein family that this protein belongs to?
Belongs to the KduI family.
Protein: SNP25_PONAB
Sequence: MAEDADMRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKEAEKNSTDLGKFCGLCVCPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMAISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG
What is the function of this protein?
t-SNARE involved in the molecular regulation of neurotransmitter release.  May play an important role in the synaptic function of specific neuronal systems.  Associates with proteins involved in vesicle docking and membrane fusion.  Regulates plasma membrane recycling through its interaction with CENPF.  Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells.
What are the official names of this protein?
Synaptosomal-associated protein 25, SNAP-25, Synaptosomal-associated 25 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the SNAP-25 family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cell membrane; Lipid-anchor. Synapse, synaptosome. Photoreceptor inner segment. Note=Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region. Colocalizes with KCNB1 at the cell membrane (By similarity). Colocalizes with PLCL1 at the cell membrane (By similarity).
Protein: DGTL1_ZYMMO
Sequence: MKTEFASYAADPELSRGRLHDEGKGAVRGPRNAFQRDRDRIIHSMAFRRLRYKTQVFIAPESDHFRVRLTHSLEVAQIGRTIARVLRLNEDLTEALCLAHDLGHPPFGHIGENILKQALKDAGGFDHNAHSLRILTHLESPYPRWSGLNLTWEMQEGLAKHNGPIRHPNWALSAVDDAFPLELTSWPSLEAQVAALSDDIAYDNHDLDDGLRAGLIDLEEVVAQPLIAPTWQAVKTRYPDLTGKKLIAELIREQIGRMVNDSLDETRRRIAFFKPEYLPDIRQMPQAMVGFSDEMTKNERLFKKFMYQKLYHHPRLLPIAERASYVISRLVALYKDNPRLLPEDWQENWPDNEVDRQRHIVDYVAGMTDHYALKRYHQDIGAFDLV
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: FTSP_ACTPJ
Sequence: MMNLTRRQLLTRSAVAATMFSAPKTLWAAERQPLKIPPIIDVGRGRPVRLDLRPAQTQFDKGKLVDVWGVNGQYLAPTVRVKSDDFVKLTYVNNLPQTVTMNIQGLLAPTDMIGSIHRKLEAKSSWSPIISIHQPACTCWYHADTMLNSAFQIYRGLAGMWIIEDEQSKKANLPNKYGVNDIPLILQDQQLNKQGVQVLDANQKQFFGKRLFVNGQESAYHQVARGWVRLRIVNASLSRPYQLRLDNDQPLHLIATGVGMLAEPVPLESITLAPSERVEVLVELNEGKTVSLISGQKRDIFYQAKNLFSDDNELTDNVILELRPEGMAAVFSNKPSLPPFATEDFQLKIAEERRLIIRPFDRLINQKRFDPKRIDFNVKQGNVERWYITSDEAVGFTLQGAKFLIETRNRQRLPHKQPAWHDTVWLEKNQEVTLLVRFDHQASAQLPFTFGVSDFMLRDRGAMGQFIVTE
What is the function of this protein?
Cell division protein that is required for growth during stress conditions.  May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.
What are the official names of this protein?
Cell division protein FtsP.
What is the protein family that this protein belongs to?
Belongs to the FtsP family.
What are the subcellular locations of this protein?
Periplasm. Note=Localizes to the division septum.
Protein: ZBT8A_RAT
Sequence: MEISSHQSHLLEQLNEQRRQDVFCDCSILVEGKVFKAHRNVLFASSGYFKMLLSQNSKETSQPTTATFQTFSPDTFTVILDFVYSGKLSLTGQNVIEVMSAASFLQMTDVISVCKTFIKSSLDISEKEKDRYFSLSDKDTGSNGVERPSVYSSSWQEDGGSPRSHLSPDQGPAIVSGKPWNKYSYHPASQRSPQPPLAKHEQRKDPIKKTKHLRLPQPSEVVHFKSGKGDARTSDSGHHVSQSEEQVQVDAEVDPVSAGYPYSQGPEVASRSFPDNLPRLRFKCPYCTHVVKRKADLKRHLRCHTGERPYPCQACGKRFSRLDHLSSHFRTIHQACKLICRKCKRHVTDLTGQVVQEGTRRYRLCNECLTEVGMDSLPADLETEQHRVSPADGDKDCRWHLSEEENRSYVEIVEDGSADLVIQQVDDSEEEEEKEIKPNIR
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 8A.
What are the subcellular locations of this protein?
Nucleus.
Protein: GPMA_PARL1
Sequence: MPNLLVLVRHGQSEWNKKNLFTGWRDPGLTEQGMEEAREAGQAIKAKGLVFDVAYTSALSRAQETNRIVLEELGQGDIEIIENEALNERDYGDLSGLNKDDAREKWGEEQVHIWRRSYDIPPPGGESLKMTAERVLPYFEKEILPRVLKGERVLIAAHGNSLRSLVMQLDKLSQEQVLALNIATGAPIVYELDDKGGVVRKEMLIEREAH
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: RN121_XENLA
Sequence: MAAVLEVEIGGEAVREAAGEEMDLSELAPEERWRVEHARMHAKHRGHEAMHAEMVLILIATLVVAQLLLVQWKQRHQRSYNMVTLFQMWIVPVYFTVKLHWWRFLGIWIVFSIITAYITYKATRKPLLQTTPRLVYKWFLLLYKMSYATGIVGYIAVMFTLFGLNLLFRIKPEDAMDFGISLLFYGLYYGVLGRDFAELCADYMASTIGFYSASGMPTKHLSDSVCAVCGQQIFVDVNEEGIIENTYRLSCNHVFHEFCIRGWCIVGKKQTCPYCKEKVDLKRMFSNPWERPHVMYGQLLDWLRYLVAWQPVIIGLVQGINYCLGLE
What is the function of this protein?
E3 ubiquitin ligase which accepts ubiquitin and transfers it to substrates thereby promoting their degradation by the endoplasmic reticulum-associated degradation (ERAD) pathway which is a pathway involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (By similarity).  May regulate the unfolded protein response to reduce endoplasmic reticulum stress (By similarity).
What are the official names of this protein?
E3 ubiquitin ligase Rnf121, RING finger protein 121.
What is the protein family that this protein belongs to?
Belongs to the RNF121 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TRUA_MYCMS
Sequence: MKTGILLSLCYDGSNYHGWINQTNAISIQTTLNKAIKKVIKTGQFKTIGASKTDTNVHALDQKVLLIIYFTPILEKFIKAINKALPSDIKILDAKFVDPNFNIREVEYKIYHYYINDHQFDIFTNRYEYFWKHQKIDIIKLQEIFNLFIGEHEFKLFSGLKENEWNQYQTKRTIDDIKVLRINNKVVIQFKASGFIRYQIRIIIANCLNAYLNHKISTTKLVEMLQGIGKKTPFIIDAKGLVLQKIQFNKN
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RS5_MESH7
Sequence: MDKKLENQKDLLNQDPKVELNSQSVAKNPLNSREVKPIQRRRPLRKNARDKNSKPEFEERVIAIHRVVKVVKGGRRFSFSAFAVVGNKKGRVGFGHGKANEVQDAVKKAIKDAQNRLVSVPIYRKSTVPHEIAVKYLASKILIKPAPRGKGIVASNTVRAVVELAGYTDIYTKTYGSRTKINVVRATLKALLKLRTINQVAELRDLSPQQAQAQKV
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: UP07_PINHA
Sequence: DGVTDPLEVNVVK
What are the official names of this protein?
Unknown protein 7.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: ZGPAT_DROAN
Sequence: MDEYEAQLLVVEQALENATDEHQRQELLALKENLQELLSLTRGGTEDDAATDDDSQNADNLDNELERLKSELNDMEATGASKSNENEVQQLADLRTKYSSMVGEKCSAPHEHSWGAISYHNALICGVDDEVIINGDGALDARLRVLFTNPTHREMLPCSYYLEGECRFDEARCRYSHGALVTGSSIRKYNPPDFHKLSRSCPVLAQLPDRLWHRGRVLCVNFVEQVCRVRLDGQDHKERERDFKFEELFPLTTDQEDELTSEDSSSVNDGSSDEEESDMDDLEAARRARMVELSLFTFKPTEKLGAWEEYTRGIGSKLMEKMGYIHGTGLGSDGRGIVTPVSAQILPKGRSLDACMELREAANGDKDYFSVERKLQRAQRRQKKANEKAYVRESQRTDVFSFLNSSVLGSDNKQQAEPEAKKAKANDLQQHSTKTLNVETVRIADDIRRKQRDIAKVQQSLDRNTGDVQLQKRLQAQMHNQKQELATLQAQERSLSKEQQTRKSKNKMFEF
What is the function of this protein?
Transcription repressor.
What are the official names of this protein?
Zinc finger CCCH-type with G patch domain-containing protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS8_SYNJA
Sequence: MCALRYLRPDLLHLKPYDAVPPQAADKLDANEFPWDWPVGFKQKLSLLWEKGIPSNRYPDAHHQGLKQAIAAYAGADPAQISLGNGSDELIRSLLIATCVGERGSVLVAEPTFSMYAILAQSLGIPVVRVPRHPETFALDLGRCQQAVAEQRVRVVCLVDPNSPTGNGLSTAEWEWVEGLPAEILVILDEAYFEFSQHTALPKLAEHPNWVILRTFSKAFRLAAHRVGYAIGHPQLIQVLDSIRLPYNLSAISQWAVQIALEHAEEFLADLPLIRQERDALYQALQELPGVRVWPSQANFLYFRVAGWDPQDLQRAWQELGTCVRCTGGGLRLTVGTPEENQRALERLRQILR
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: ATPG_LISIN
Sequence: MASLIDIKQRITSTRKTSQITKAMQMVSAAKLGRAESNARSYEPYVSKIKDVVTHVASTGNSSDHPMLVSRPVHRTGYIVLTSDTGLAGSYNSSVIKEVFQEINKKHTSSDEYAIITVGRSARDFFKARQMNVVLEVQGITDHPIFAEIKDIASNTVQMFEDGVYDEVFIYYNHHINSISSELRKEQLLPLTEFHEKGKETDVDLTTYEFEPSEQEILEVLLPQYVESLIFGALLDAKAAEHAARMTAMRSATDNASDLISDLSLQYNRARQAAITQEITEIVGGAAALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RPOB_SYNC1
Sequence: MAYSVANNQLLRKHFSTIKGIIEIPNLIDIQKNSYKRFLQAGLPPSARKNIGLEAVFRSVFPIRDFSETCSLDYVSYSLGTPKYDVGECHQRGMTFAAPVKVCVRLVSWDVDKESGVQAIRDIKEQEVYFGEIPLMTENGTFIINGTERVIVSQLHRSPGVFFDHDKGKTHSSGKILYNARVIPYRGSWLDFDFDHKDLLYVRIDRRRKLPATVLLKALGYSAEELLNYYYQVETVTVDGDSFKKKVNLDLLAGQRASTDVLGNDGEIIVKANRKFTKAAIRKLADSNVEYIPVSEEEIVGKVASTDIVDVSTGEVIVECNEEISESKLEELRTRGIVEFNILFIDHLHVGPYLRETLLLDRMATPEDARIEIYRRLRPGDPPTIKSANALFESLFFNPERYDLSVVGRIKLNYKLGLQSPEDQTTLTKDDILEVVRYLIGLRDGRGTIDDIDHLGNRRVRAVGELLENQYRVGLVRMERAIKERMSLQEVDSLMPHDLINSKPVSAVVKEFFGSSQLSQFMDQTNPLSEITHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLIASLSTYARINEHGFVETPYRIVEQGKVTNEIRYFSALEEGGHAIAQANAPLDDDGRFLNELVNARQNGEFVLIQREEIGLMDVSPKQLVSVAASLIPFLENDDANRALMGSNMQRQAVPLLRADAPLVGTGMERIVAHDSGAAVVARHNGVVESVDASRIVVKIDEGEVDEDGTGVDIYNLIKFARSNQNTCLNQKPIVKVGDRVASGGIIADGPSTEWGELALGQNVLVAFMPWEGYNFEDSILISEKLVKEDRYTSIHIEELECVARDTKLGKEEITNDIPNLGEDALKDLDESGIVRIGAEVKPGDILVGKITPKGETQLSPEEKLLRAIFGEKAGDVRDTSLRLPPGVEGVVIGARVFSRKGSDKDSRTEYIEKTEIEKLLKDQHDEIRIIRESTHGKLESLLVGQTSASALFDAAGKELLGQGEKITSEVLAEVPFARWREISLLDASENEEKLSAIMTSLAQREELIKAVFADKIEKIKRGDDLPPGVIKMVKVYIAIKRKLSVGDKMAGRHGNKGVLSRVLPEEDMPYMADGTPVEIVLNPLGVPSRMNVGQILETHLGLAARGLGVQIQEHLDRYYTPEAMRTKIGECYEDDRVAEFVDALPDDEVMQLARQLSRGVPMASPVFEGVTEEQMKNQMERAGFASSGQMTLYNGKTGEAFKEKVTVGIMYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRLGEMEVWAMEAYGAAHALQEFLTVKSDDVTGRTRMYEAIVKGKHTLEAGLPESFNVLIKELQSLCLDVELLEEQE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: TOP3_BACAH
Sequence: MAKSVVIAEKPSVARDIARVLKCDKKGNGYLEGSKYIVTWALGHLVTLADPESYDVKYKKWNLEDLPMLPERLKLTVIKQTGKQFNAVKSQLLRKDVNEIIVATDAGREGELVARWIIDKVRINKPIKRLWISSVTDKAIKDGFANLKPGKAYDNLYASAVARSEADWYIGLNATRALTTRFNAQLNCGRVQTPTVAMIANREDEIKNFKAQTYYGIEAQTTNQLKLTWQDANGNSRSFNKEKIDGIVKGLDKHNATVLEIDKKQKKSFSPGLYDLTELQRDANKKFGYSAKETLNIMQKLYEQHKVLTYPRTDSRYISSDIVGTLPERLKACGVGEYRPLAHKVLQKPIKANKSFVDDSKVSDHHAIIPTEGYVNFSAFTDKERKIYDLVVKRFLAVLFPAFEYEQLTLRTKVGNETFIARGKTILHAGWKEVYENRFEDDDVTDDVKEQLLPRIEKGDTLTVKLIMQTSGQTKAPARFNEATLLSAMENPTKYMDTQNKQLADTLKSTGGLGTVATRADIIDKLFNSFLIEKRGKDIHITSKGRQLLDLVPEELKSPTLTGEWEQKLEAIAKGKLKKEVFISEMKNYTKEIVSEIKSSDKKYKHDNISTKSCPDCGKPMLEVNGKKGKMLVCQDRECGHRKNVSRTTNARCPQCKKKLELRGEGAGQIFACKCGYREKLSTFQERRKKESGNKADKRDVQKYMKQQKKEEEPLNNPFAEALKKLKFD
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 3, DNA topoisomerase III.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: GCST_MYCLE
Sequence: MTDAPELLKGPLEDRHRELGANFAEFGGWLMPVSYAGTVSEHSATRNAVGLFDVSHLGKALVRGPGAAQFVNSVLTNDLGRIRPGKAQYTLCCSESGGVIDDLIAYYVDDDEIFLVSNAANTAAVVDALQAVVPAGLTIINQHRSHAVLAVQGPRSTDVLGELGLPTGIDYMGYVDASYAGVPVRVCRTGYTGEQGYELLPPWESADVVFDALVAAVVDARGEPAGLGARDTLRTEMGYPLYGHELSLDISPLQARCGWAIGWKKDAFLGRDALLAEKAAGPRRLLRGLRMAGRGVLRPGLTVCAGDIPIGVTTSGTFSPTLQVGVALALIDSEAAVQDGQQIIVDVRGRAVECEVVRPPFIEVKTR
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: KDSA_RICPR
Sequence: MKKVVKLNNIKIGNDLQFVLIAGPCQIEGKDHALFMAEKLMKLTSKLSIPFIYKSSFDKANRTSINGIRGLGIEKGLEILSKVKSEFDCPIITDVHSESQCIETAKVVDILQIPAFLCRQTDLLKAAAKTGKIVKVKKGQFLAPWDMKNVQKKLEVFGAKDILFTERGSCFGYNNLVSDMRSLAIMSELNVPVVFDATHSVQQPGGRGGSSGGERKYVELLAKAAISVGIAGIYMEVHQDPDNAPSDGPCMIKLDNLESILIKLKKYDKITKEIV
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_BORPD
Sequence: MKRIGLLGGSFDPVHLAHLALARAAAAELRLDSVQLIPAANPWQRAPLRASAGHRLRMIELAIDGEPQLAVNPVELERGGPTYTIDTVRALPADAHYVWLLGTDQLANFCTWRQWQAIAGHVDLAVAARPGAPLAAPAELASWLAAHRRRLIRLPFSPMAISASDIRGRLARGASTAGLLPATVARYIARHGLYR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: ACTP_SHIFL
Sequence: MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTSADVASYRLKQGPIRILSACGSLVVVALYLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSEAMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANPEYKDAAGHLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVADLTLAGASAVSHDLYANVFKKGATEREELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMLGGWLGLITAVVLMILGPTIWVQILGHEKAIFPYEYPALFSISVAFLGIWFFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH
What is the function of this protein?
Transports acetate.
What are the official names of this protein?
Cation/acetate symporter ActP, Acetate permease, Acetate transporter ActP.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: B3GN5_RAT
Sequence: MRVFVSSRRVKRWQFFHLFAICFILSFMVFWGPINNYIMSHMKSYSYRYLINSYDFVNDSLSLKHSSVQPHHPYLINHREKCQAQDVLLLLFIKTAPENYERRSAIRKTWGNENYVQSQLNANIKILFALGTPHPLKGKELQKRLIWEDQVYHDIIQQDFTDSFHNLTFKFLLQFGWANTFCPHARFLMTADDDIFIHMPNLIEYLQGLEQVGVRDFWIGHVHRGGPPVRDKSSKYYVPYEMYKWPAYPDYTAGAAYVVSNDVAAKIYEASQTLNSSMYIDDVFMGLCANKVGVVPQDHVFFSGEGKIPYHPCIYEKMITSHGHSQDLQDLWVEATDPKVKDISKGFFGQIYCRLIKIVLLCRLTYRNSYPCRAAFA
What is the function of this protein?
Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures.  Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc(4)Cer; paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide (nLc(5)Cer), respectively.  Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development.
What are the official names of this protein?
Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase, Lactotriaosylceramide synthase, Lc(3)Cer synthase, Lc3 synthase, UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5, BGnT-5, Beta-1,3-Gn-T5, Beta-1,3-N-acetylglucosaminyltransferase 5, Beta3Gn-T5.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: RL30E_METVS
Sequence: MRRRYSMDINRAIRVAVDTGNVVLGTKQAIKNIKHGEGKLVIIAGNCAKDVKEDIFYYTKLSETPVYTHQVTSIELGAICGKPFPVSALLVLEPGNSAILNINNE
What are the official names of this protein?
50S ribosomal protein L30e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL30 family.
Protein: COBT_SHEHH
Sequence: MFDIKLINTEFDDVIQQKIDTKTKPLGALGDLETLALQIARVLGKDKPQIRNPKMMVFAADHGIADSGVSIAPSEVTTQMVVNFINGGAAINVFTRQVGFDLEVIDCGILKPIENLEGVIDQRLGAGTGPIHKRAAMTLGAVKQGFKMATDRVELHHQNGCNLIALGEMGIGNTSSAAAIMAALTGMKAEDCVGRGTGIDATTFKRKKMLVEQALLMHHCELDDPMQVLACLGGFEIVQMTGAMLAAAERNMLVIVDGFIATAAALAAIKINPNVREYMIFAHQSDEKGHVMMLEFLQAKPLLKLGMKLGEGTGAALALPLIQAAVNFYNEMASFADAGIEI
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.