PharMolix/UniProtQA huggingface dataset:
Protein: IF2_CLOB1
Sequence: MAKIRVYELAKELNISSKELITLLEEEFSVEVKNHMSAIEDEDANLIKELLSGKEKSEKTKEEDDEIETTAKNPIKESMNNKKSNKRDDKNEKVNTENAEDMGIITMTSDTITVKEISDKLEKSYAEVIKELMLMGVMASVNQEINFEMAEKLAAKFDMEILKEDEDEKEDLEDILKDNEEEEYLQKRSPIITVMGHVDHGKTSLLDAIRKSKVTSTEAGGITQHIGAYTVELNGEAITFLDTPGHAAFTAMRARGAQVTDIVILVVAADDGIMPQTQEAISHCKAANVPLIVAINKIDRPGANIDKVKQELTEYGLVAEDWGGDTICVPVSAHTKEGIDDLLEMILLSSEILELKANPNRKAKGTVVEAKLDKGRGPVATLLIQNGTLRVGDSIVVGSTYGRIRAMFNDKGRNIESAGPSTPVEILGLSEVPEAGDKFYQVKEEKTARGIADKRKEKIRDEYLQSTHKVSLEDLYNQIQEGTVKELGLIVKADVQGSVEALKQSLEKLSTEEVKVRVIHGGVGAINETDVTLATASNGIILGFNVRPDNNAIIASERDGVDIKTYRVIYDAIEDIKSAMLGMLEPEFKEVVIGTAEVRQVYKISSVGTIAGAYIQTGKLARNAGARVIRDGIVIFESELASLKRFKDDAKEVAQGYECGLSIEKFNDIKEGDIIECFIMEEIKKKTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_ENT38
Sequence: MTIERTFSIIKPNAVAKNVIGSIFARFESAGFKIVGTKMLHLTVEQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLESENAVQRHRDLLGATNPANALAGTLRADYADSFTENGTHGSDSVESAAREIAYFFAEGEVCPRTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LFTY2_MOUSE
Sequence: MKSLWLCWALWVLPLAGPGAAMTEEQVLSSLLQQLQLSQAPTLDSADVEEMAIPTHVRSQYVALLQGSHADRSRGKRFSQNFREVAGRFLMSETSTHLLVFGMEQRLPPNSELVQAVLRLFQEPVPRTALRRFERLSPHSARARVTIEWLRVREDGSNRTALIDSRLVSIHESGWKAFDVTEAVNFWQQLSRPRQPLLLQVSVQREHLGPGTWSAHKLVRFAAQGTPDGKGQGEPQLELHTLDLKDYGAQGNCDPEVPVTEGTRCCRQEMYLDLQGMKWAENWILEPPGFLTYECVGSCLQLPESLTIGWPFLGPRQCVASEMTSLPMIVSVKEGGRTRPQVVSLPNMRVQTCSCASDGALIPRGIDL
What is the function of this protein?
Required for left-right asymmetry determination of organ systems in mammals.
What are the official names of this protein?
Left-right determination factor 2, Left-right determination factor B, Protein lefty-2, Protein lefty-B.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: PANC_NAUPA
Sequence: MKILNSPKEAINYTKSLNGSIGFVPTMGALHEGHLSLIEKARKENDYVIVSIFVNPTQFLPGEDLDKYPRRLEADFEICKRAGVDAVFTPTPENMYSNDEVLIKAPKIKGYILEGFNRPGHFDGVLQVVNKLFNIIRPTRAYFGKKDAQQLYLIKQMVNNFFFDIEIVECETKREKDGLALSSRNIYLSEEERKRALSISKALKRAAKLSSKTKNIEEIEKEMLEILDVDELQYIAFVDRDFNHIDEIKPGNTIILLAAKVGSTRLIDNIWI
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGH_DECAR
Sequence: MKRLVLISLVLAAGCSTVPPTNVHQPMTARPSPRFEMANGNGSIYQAASSRPLFEDRRARFVGDTITVKITESTTASTKSNNKVDQSNAQKYGLGASTGMFGRVLPGAMDMSASSSTAFSGKGEAANNNIFTGNMTVTVIDVMPNGNLLVSGEKQVAIGSEQEFVRISGVVNPSFVDAFNVVDSSKIADARIEYKSSGQVSDGQVMGWLARFFLNVMPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: CYB_OSPRU
Sequence: MTNLRKTHPLIKIVNHSFIDLPAPSNISAWWNFGSLLGACLIIQILTGLFLAMHYTADTLTAFSSVAHICRDVNYGWLIRNLHANGASMFFMCLFLHVGRGIYYGSYLYKETWNIGVILLLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPSGINPDSDKIPFHPYYTIKDALGFMLMLLILLTLALFSPDMLGDPDNFSPAKPTEHSSHIKPEWYFLFAYAILRSIPNKLGGVLALLASILILLIIPLLHTSKQRSLMFRPISQTLFWILTANLITLTWIGGQPVEQPYIIIGQVASISYFLLIIVLMPLAGLFENYMLEPKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LAT3B_LACTA
Sequence: MKTYAVLLALVVAFVCIAESTGYPVEDLEDDELTELEAEALLEDLLEDLELEDLDYNEEARSWASMAKKLKEYMEKLKQRAG
What is the function of this protein?
It has antimicrobial activity against Gram-positive bacteria (A. globiformis VKM Ac-1112 (MIC=0. 7 uM), and B. subtilis VKM B-501 (MIC=2. 9 uM)), Gram-negative bacteria (E. coli DH5-alpha (MIC=23 uM), E. coli MH1 (MIC=28 uM), and P. aeruginosa PAO1 (MIC>45 uM)), and yeasts (P. pastoris GS115 (MIC=23 uM), and S. cerevisiae Y190 (MIC=23 uM)).  Does not have hemolytic against rabbit erythrocytes.  Causes paralysis, but is not lethal when injected into insect (M. domestica) larvae.
What are the official names of this protein?
M-zodatoxin-Lt3b, M-ZDTX-Lt3b, Latarcin-3b, Ltc-3b.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 03 (latarcin) family. 03 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: METK_PSYCK
Sequence: MREYNLFTSESVSEGHPDKMADQISDAILDAILRQDLHARVACETLVKTGAVVLAGEITTTANIDVERIVRDTVNGIGYHHSDLGFDGETCAVINMLGKQSPEIAQGVDRADPEEQGAGDQGLMFGYASNETEVLMPAPIEYAHRLMERQSELRRAGELPWLRPDAKAQVTLKYDGNKPVAIDAVVLSTQHDPSISQADLQEAIMESIIKQVLPAELLHAGTRYHINPTGKFVIGGPVGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAVRYVAKNIVAAGIADRCEVQVSYAIGVAEPTSISINTFGTNKISNDEIISLIRTHFDLRPYGITRMLNLLQPMYQQTASFGHFGRQGSETAFTWEKTDKAKILKADAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_METVS
Sequence: MNKNYKNNLNESINNPSKILNEKIILGLDEAGRGPVLGPMVISVVKVTEKDLDKINSLDLKDSKQLTKKRREEYYNIINECFEVQKIVLAPEKIDEYMKTSNLNKIELSAFSKLSNHFLKEYENVKIFIDACSSSEQSFLNQFKAKLINKKVEIIAEHKADEKYKIVSAASIIAKVTRDNIIESYKEEFGDIGSGYPGDPKTKEFLKRFVKEHKKLPKIARGSWATSKKLLKEFEESKLHKWVK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_METVS
Sequence: MKKGEKLEIKLFGKWDSTSVTVKDPSLKSHISLNPVLIPHTAGRNSKKMFDKNKMHVVERLANKLMATQVNTGKKNEVLSIIEEALTIVENRTKENPIQVVVDALENSGPREETTRISYGGIAFLQSVDVSPSRRLDTAFRNISLGASQGAHKSKKSIAQCLADELVAASKADMQKSFAVKKKEEKERVAQSAR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: F3GGT_ACTCC
Sequence: MGAPTFHIAMYPWFALGHLTPFLHLSNKLARKGHKISFLIPTKTQQKLEPFNLHPDLITFIPVTVPHVDGLPLGAETTSDVPYPLQTLLMTAMDRTEKYVEDVFLGLKVDVVFFDFTHWMPSVAKRLGIKSVNYCIISPATIGYTMSPARQLQGRELTEADLMVTPLGYPDSSIRLRTHEARAFAARRVMKFGGDTRFCDRNFISFSECDAMGFKTCREIEGPYCDFLESQFEKPVLLSGPVIPEPPTSPLEEIWAKWLGGFRDGSVIYCAFGSECTLKMNQFQELLLGLVLTGMPFLAVLKPPIGAKSVEEALPEKFETSVEGRGVVHEGWVQQQLILEHPSVGCFITHCGSGSLSEALFNKCQLVLLPNVGDQIINARMMSQNLKVGVEVEKGEEDGLFTGESVCRAVRDAMEEGSEVAKEVRDNHAKMREFLLNKDLESSYIDNFNKKLQDLLG
What is the function of this protein?
Xylosyltransferase involved in anthocyanin biosynthesis by catalyzing the xylosylation of cyanidin 3-O-galactoside to form cyanidin 3-O-[2-O-(-xylosyl)-galactoside] (PubMed:21175894).  Required for the accumulation of anthocyanin in red-fleshed kiwifruit varieties (PubMed:21175894).
What are the official names of this protein?
Cyanidin 3-O-galactoside 2''-O-xylosyltransferase FGGT1, Flavonoid 3-O-glycoside glycosyltransferase 1, UDP-xylose flavonoid O-glycosyltransferase 6B, AcUFGT6b.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: COW3_CONTE
Sequence: MGKLTILVLVAAVLLSAQVMVQGDGDQPADRKAVPREDNPGGASGKLMDVLRPKKCVLYPWCG
What is the function of this protein?
Its target is unknown, but this toxin may modulate voltage-activated calcium channels (Cav) or calcium-dependent potassium channels (KCa).
What are the official names of this protein?
Leu-contryphan-Tx.
What is the protein family that this protein belongs to?
Belongs to the O2 superfamily. Contryphan family.
What are the subcellular locations of this protein?
Secreted.
Protein: YMJA_ECOLI
Sequence: MNHDIPLKYFDIADEYATECAEPVAEAERTPLAHYFQLLLTRLMNNEEISEEAQHEMAAEAGINPVRIDEIAEFLNQWGNE
What are the official names of this protein?
Uncharacterized protein YmjA.
Protein: RL32_SALAR
Sequence: MAVQQNKPTRSKRGMRRSHDALTAVTSLSVDKTSGEKHLRHHITADGYYRGRKVIAK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: MT2_CICAR
Sequence: MSCCGGNCGCGSSCKCGSGCGGCKMYPDMSYTEQTTSETLVMGVASGKTQFEGAEMGFGAENDGCKCGSNCTCNPCTCK
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein-like protein 2, MT-2.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 15 family.
Protein: THII_ESCF3
Sequence: MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVVRHWDNIEVRAKDESQRLAIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALVQYRDQLEGKTFCVRVKRRGKHDFSSIDVERYVGGGLNQHIESARVKLTNPDVTVHLEVEDDRLLLIKGRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEIGVRQVAHYLWNRFGSSHRVRFVAINFEPVVGEILEKIDDGQMGVILKRMMVRAASKVAERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTEDFARTMPEYCGVISKSPTVKAVKSKIEAEEEKFDFSILDKVVEEANNVDIREIAQQTEQEVVEVETVNGFGPNDVILDIRSVDEQEDKPLRVEGIDVVSLPFYKLSTKFGDLDQNKTWLLWCERGVMSRLQALYLREQGFNNVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y233_METJA
Sequence: MGTIESYLTNSYNYIIFNFKKLCIGGLMSAIVGAMSGVTTAFIDLFMERANYDIMHIIMSFLIYFGIIFIIGLIVSAIIGGYNVRIMKTTVEGLNVAPDWNNITDLLYRGILYIVGLVLLNIIFYFIPAILFVFGIFSLYISKIIGAFLIIISILIFIISVISLWLYSKLAEVNYSVKGFYGFFEFKEIFKMIGIRYIILVIIIAIINFIISLIVVLPLNIIDIFISYSALANSILTIIYISIKGISYALSTFVDFYLGVFSIRAVALYYKDRKGIT
What are the official names of this protein?
Uncharacterized protein MJ0233.
What is the protein family that this protein belongs to?
To M.jannaschii MJ1189.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: APT_THEMA
Sequence: MFKLDLKRFIRDIPDFPQKGIVFRDITPLLRNQEAFKEAIDRMCELVFDREFDLVVAPEARGFILGAAMAYKLGKGFVPVRKPGKLPYKTVYEEYQLEYGTEQLHIHEDAIEKGQKVLIVDDVLATGGTAEALIRLVKKLGGEVVSLAFLVELSYLEPRKRLEGYDVKTLIVY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_HISS2
Sequence: MIRIGHGFDVHAFGGEGPIIIGGVAIPYEKGLVAHSDGDVALHALTDALLGAMALGDIGKLFPDTDIQYKGADSRRLLRTAYQAILDKGYQVGNVDITIIAQAPKMRPYIDSMRTVIAQDLHCDIEQVNVKATTTEKLGFTGRSEGIACEAVVLLIKQNGTK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: TX120_LYCSI
Sequence: MMKVLVVVALLVTLISYSSSEGIDDLEADELLSLMANEQTRKECIPKHHECTSNKHGRCRGNFFKYKCQCTTVVTQDGEQTERCFCGTPPHHKAAELVVGFGKKIFG
What are the official names of this protein?
U1-lycotoxin-Ls1h, Toxin-like structure LSTX-A20.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 04 (U1-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PNP_PARXL
Sequence: MTMFNKIVKEFQWGQHKVRLETGEIARQASGAVIVDVEDTVVLATVVGARTAKPGQDFFPLTVDYLEKTYAAGKIPGGFFRREGRPSEGETLISRLIDRPLRPLFPEGFYNEVQVVIHVLSLNPEIPADIPALIGASAALAVSGLPFNGPVGAARVAYINNEYVLNPTRPQMKESALDLIVAGTERAVLMVESEAQQLSEEVMLGGVVFGHEQMQIAIDAIHDLVREGGKPEWDWQPAAKNEPLIARVTELAQADLLAAYQLRDKQARSAKLKEIYAATSAKLEEDAAAGGTVAADKATVGNVLFDIEAKIVRTQILNGEPRIDGRDTRTVRPIEIRTGVLPRTHGSALFTRGETQALVVATLGTKGDEQNIDALEGEYRERFMLHYNMPPFATGETGRVGSPKRREIGHGRLAKRALAACLPSADEFGYSIRVVSEITESNGSSSMASVCGGCLALMDAGVPMKAHVAGIAMGLILEGNKFAVLTDILGDEDHLGDMDFKVAGTEQGVTALQMDIKIQGITREIMQVALAQAKEGRLHILGKMTSAVSGANTVLSDYAPRMITIKINPEKIRDVIGKGGSVIRALTEETGTTIDISDDGVVTIASTSSEGMAEAKKRIENITLEVEVGQVYEGTVLKLLDFGAIVNILPGKDGLLHISEIANERIKDINDYLKDGQQVKVKVIQTDEKGRVRLSAKALLNDAANGAPQGEPTPQQ
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_EHRCR
Sequence: MIGSLTGIIEEIYNNYIILNVGNVGYIIYVSHKVLQSCKTGNNIKLYIETYVNRDNLTQLYGFLDKQEQDYMRMLVTINGINHKTAISILSKLSPEQIFSAVVSNNKNAFRGNGIGEKLAGRITTELQYKISKMPIEETLIIKEDDSLAALISLGYDKLKAFNAIQEIKANFPDDSIQEIIRKALQKLSQ
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: PSB_GEOOG
Sequence: MSEYSAGRSGFSPAYLDRVGSSFTDFLAAAAPHLLPGSRPVPQIPVGNVTPHGTTIVSVTYDGGVLMGGDRRATMGNLISSREIEKVYPADAWSVIGIAGAAGIAIEMVRLYQVELEHYEKIEGLTLSLDGKANRLAQMIRGNLGAALQGLAVVPLFAGFDLDAAPGAAPGRIFSYDVTGGNYEERGYSAVGSGSLFARNSLKKTWRPNLDGDAATRSLVEALYDAADDDSATGGPDPVRRLYPIVYRVDAEGAVRVPDDEIAAVATRITDERSAADGQG
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PrcB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_NITMS
Sequence: MKYIVGARGSQLSVAQTNLVIAELKKAHPDTEYEIKTITTKGDTDSRPLFTIDQKGIFEKEIDRAVAQKEVDFAVHSLKDVPSELDDNLVLACIPKRETVNDVFISPDGSTLDSIKPGSVIGTSSLRRAVQVSRKRPDVTVKPIRGNIETRIKKASGENYDAIVLAKAGISRLGVDVKYTELSTDDFSPSPGQGAIAIVARADDSKTIEMLKKIEDPDSRLEIEAERALSDFVDSGCRFPVGAYAKSNGSEMTLTVTAFSVDGKQFLHVSKTGDKNNPKSLGQSAGEELREKGVNDLALNWREKVEEWNKT
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Probable porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: SDHE_XANC8
Sequence: MEKEMDEDTLLKKLRWRCRRGMRELDQLFGRYLDRRWAQAPAAERAVFLQLLDCEDDKLWRWFMGYEACPDADNAALIADIRAMPA
What is the function of this protein?
An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins.  Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
What are the official names of this protein?
FAD assembly factor SdhE.
What is the protein family that this protein belongs to?
Belongs to the SdhE FAD assembly factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_HELPJ
Sequence: MLMPKRTKYRKQMKGRNRGKAHRGNSIAFGDIAIKAIEHGRIDSRQIESARVAMTRHIKRAGKVWIRVFPDKPLTAKPLETRMGKGKGSVEKWVMNIKPGRIVYEMLGIEEGLAREALALSQSKLPFKTKIVTCESENEIY
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: LYS_BPMV1
Sequence: MTKTYGVDVAVYQPIDLAAYHKAGASFAIVKLTEGVDYVNRRGPSRWTAPGLTTSTLMPTISRSFGSSVSRAKKEAAYFLKEAKKQDISKKRMLWLDWEAGSGNVVTGSKSSNTAAILDFMDAIKAAGWRPGLYSGASLMRTAIDTKQVVKKYGTCLWVASYPTMAAVSTADFGYFRQWTGSPSGSLPVTAWPGRRRERCSG
What is the function of this protein?
Helps to release the mature phage particles from the cell wall by breaking down the peptidoglycan.
What are the official names of this protein?
Lysozyme, Endolysin, MV1 lysin, Muramidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 25 family.
Protein: FABZ_STRGC
Sequence: MIDINAIKEALPHRYPMLLVDRVLEVSEDEIVALKNVTINEPFFNGHFPQYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQLIMTAKFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGQ
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLK1_XENLA
Sequence: MAQVAGKKLTVAPEAAKPPGIPGSSSAVKEIPEILVDPRTRRRYLRGRFLGKGGFAKCYEITDLESREVFAGKIVPKTMLLKPHQKDKMTMEIAIQRSLDHRHVVGFHGFFEDNDFVYVVLELCRRRSLLELHKRRKAVTEPEARYYLKQTISGCQYLHSNRVIHRDLKLGNLFLNDEMEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLGKKGHSFEVDIWSIGCIMYTLLVGKPPFETSCLKETYMRIKKNEYSIPKHINPVAAALIQKMLRSDPTSRPTIDDLLNDEFFTSGYIPSRLPTTCLTVPPRFSIAPSTIDQSLRKPLTAINKGQDSPLVEKQVAPAKEEEMQQPEFTEPADCYLSEMLQQLTCLNAVKPSERALIRQEEAEDPASIPIFWISKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLIMYNDGDSLQYIERNNTESYLNVRSYPTTLTKKITLLKYFRNYMSEHLLKAGANTTPREGDELARLPFLRTWFRTRSAIILHLSNGTVQINFFQDHTKIILCPLMAAVSYIDEKREFRTYKLSLIQEFGCCKELASRLRYARTMVEKLQSSKSAVAHVKASA
What is the function of this protein?
Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase-promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis.  Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains.  Phosphorylates cdc25, pkmyt1/myt1, stag2/sa2, tpx2.  Plays multiple essential roles during mitosis.  Phosphorylates the N-terminal domain of cdc25, which leads to cyclin b-cdc2 activation and mitotic entry.  Also required for organization of bipolar spindles, and for exit from mitosis.  Involved in kinetochore functions and sister chromatid cohesion by phosphorylating stag2/sa2.
What are the official names of this protein?
Serine/threonine-protein kinase PLK1, Plx1, Polo-like kinase 1, PLK-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Midbody. Note=localization at the centrosome starts at the G1/S transition (By similarity). Localized at centrosomes at prophase, spindles at metaphase, and at the midbody during cytokinesis. Localization to the centrosome is required for S phase progression (By similarity).
Protein: COAX_CLOBL
Sequence: MILVLDVGNTNIVLGIYKNKELIANWRLATDNKRTADEYGIQVIELFSHNNLSFSDIEGVIISSVVPNIMYSLEHMISKYFNIKPIIVGPGVKTGINIKYDNPKEVGADRIVNAVAAHEIYKKPLIIIDFGTATTFCAVTKEANYLGGTICPGIKISSDALFDKAAKLPRVELVKTPGVICKNTVASIQSGIIYGYAGQVDYIVSKMKKEMMDLGEEEPFVVATGGFAKLISEESKSIDEINAILTLEGLRVIYEKNK
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.