PharMolix/UniProtQA huggingface dataset:
Protein: HLYB3_ECOLX
Sequence: MDSCHKIDYGLYALEILAQYHNVSVNPEEIKHRFDTDGTGLGLTSWLLAAKSLELKVKQVKKTIDRLNFISLPALVWREDGRHFILTKVSKEANRYLIFDLEQRNPRVLEQSEFEALYQGHIILIASRSSVAGKLAKFDFTWFIPAIIKYRRIFIETLVVSVFLQLFALITPLFFQVVMDKVLVHRGFSTLNVITVALSVVVVFEIILSGLRTYIFAHSTSRIDVELGAKLFRHLLALPISYFESRRVGDTVARVRELDQIRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILFSLPCYAAWSVFISPILRRRLDDKFSRNADNQSFLVESVTAINTIKAMAVSPQMTNIWDKQLAGYVAAGFKVTVLATIGQQGIQLIQKTVMIINLWLGAHLVISGDLSIGQLIAFNMLAGQIVAPVIRLAQIWQDFQQVGISVTRLGDVLNSPTESYHGKLALPEINGDITFRNIRFRYKPDSPVILDNINLSIKQGEVIGIVGRSGSGKSTLTKLIQRFYIPENGQVLIDGHDLALADPNWLRRQVGVVLQDNVLLNRSIIDNISLANPGMSVEKVIYAAKLAGAHDFISELREGYNTIVGEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMRNMHKICKGRTVIIIAHRLSTVKNADRIIVMEKGKIVEQGKHKELLSEPESLYSYLYQLQSD
What is the function of this protein?
Part of the ABC transporter complex HlyBD involved in hemolysin export.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity).
What are the official names of this protein?
Alpha-hemolysin translocation ATP-binding protein HlyB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Protein-1 exporter (TC 3.A.1.109) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYH_CYTH3
Sequence: MEKPSLPKGTRDFGPAQMLKRQYLLQTIREIFTKYGFLPIETPAMENLSVLTGKYGDEGDQLIYKILNSGDFIQGVEQNHLQEGYKKLIPKISKKALRYDLTVPFARHVVMNRNDITFPFKRYQIQPVWRADRPQKGRYCEFMQCDADVVGTDSLLCEAEIVLMIHEAFAALGITDFVVKINNRKILSGIADAIGKEGSEAELCVAIDKLDKIGKEAVLEELKTKGFTDSQLTRLLPVFDLKGNNAEIFPLLRTILAQSSVGLKGIDELEKVFTLIEKSGLGNASIETDLTLARGLSYYTGAIFEVKILNVQMGSVCGGGRYDNLTGVFGLPNVSGVGISFGIDRIYDVMNELNLFPSQESNSTRLLICAFDENTFMHALPMVTKLRAQGINTELYPDPVKIKKQLSYADDKKIPFALLIGEDEMNQGLYSLKNLISGEQFKVTFDEVVHKLI
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB_VIBPA
Sequence: MGQFSILGFIALGGAIGACSRYLVSEFCVLLFGRGFPYGTLTVNVVGSFIMGLLIAAFENEILATEPWRQVIGLGFLGALTTFSTFSMDNVLLMQQGAFFKMGLNILLNVVLSISAAWIGFQLLMRS
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PPE12_MYCTO
Sequence: MVGFAWLPPETNSLRMYLGAGSRPLLAAAGAWDGLAEELHAAASSFGSVTSELAGGAWQGPASAAMANAAGPYASWLTAAGAQAELAARQARAAAGAFEEALAGVVHPAVVQANRVRTWLLAVSNVFGQNAPAIAAMESTYEQMWAQDVAVMAGYHAASSAAAAQLASWQPALPNINLGVGNIGNLNVGNGNTGDYNLGNGNLGNANFGGGNGSAFHGQISSFNVGSGNIGNFNLGSGNGNVGIGPSSFNVGSGNIGNANVGGGNSGDNNFGFGNFGNANIGIGNAGPNMSSPAVPTPGNGNVGIGNGGNGNFGGGNTGNANIGLGNVGDGNVGFGNSGSYNFGFGNTGNNNIGIGLTGSNQIGFGGLNSGSGNIGFGNSGTGNIGFFNSGSGNFGVGNSGVTNTGVANSGNINTGFGNSGFINTGFGNALSVNTGFGNSGQANTGIGNAGDFNTGNFNGGIINTGSFNSGAFNSGSFNGGDANSGFLNSGLTNTGFANSGNINTGGFNAGNLNTGFGNTTDGLGENSGFGNAGSGNSGFNNSGRGNSGAQNVGNLQISGFANSGQSVTGYNNSVSVTSGFGNKGTGLFSGFMSGFGNTGFLQSGFGNLEANPDNNSATSGFGNSGKQDSGGFNSIDFVSGFFHR
What are the official names of this protein?
Uncharacterized PPE family protein PPE12.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
Protein: SYA_STAAB
Sequence: MKKLKASEIRQKYLDFFVEKGHMVEPSAPLVPIDDDTLLWINSGVATLKKYFDGRETPKKPRIVNSQKAIRTNDIENVGFTARHHTFFEMLGNFSIGDYFKQEAIEFAWEFLTSDKWMGMEPDKLYVTIHPEDMEAYNIWHKDIGLEESRIIRIEGNFWDIGEGPSGPNTEIFYDRGEAYGQDDPAEEMYPGGENERYLEVWNLVFSEFNHNKDHSYTPLPNKNIDTGMGLERMASVSQNVRTNYETDLFMPIMNEIEKVSGKQYLVNNEQDVAFKVIADHIRTIAFAISDGALPANEGRGYVLRRLLRRAVRFSQTLGINEPFMYKLVDIVADIMEPYYPNVKEKADFIKRVIKSEEERFHETLEDGLAILNELIKKAKATTNEINGKDAFKLYDTYGFPIELTEEIAVQAGLKVDMTTFESEMQQQRDRARQARQNSQSMQVQSEVLKNITSASTFVGYDTATAQTTLTHLIYNGEEVSQVEAGETVYFMLTETPFYAVSGGQVADTGIVYNDNFEIAVSEVTKAPNGQNLHKGAVQFGQVNVGATVSAEVNQNDRRDIQKNHSATHLLHAALKSVLGDHVNQAGSLVEADRLRFDFSHFGPMTNDEIDQVERLVNEEIWKGIDVNIQEMDIASAKEMGAMALFGEKYGDVVRVVNMAPFSIELCGGIHVRNTSEIGLFKIVSESGTGAGVRRIEALTGKAAFLYLEDIQEKFNTMKSQMKVKSDDQVIDKLTQLQDEEKALLKQLEQRDKEITSLKMGNIEDQVEEINGYKVLVTEVDVPNAKAIRSTMDDFKSKLQDTIIILASNVDDKVSMVATVPKSLTNNVKAGDLIKQMAPIVSGKGGGRPDMAQGGGTQPENISKSLSFIKDYIKNL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_COXB2
Sequence: MSTQLRAAEISDIIESRIEKFGIKAEERTEGTILNIKDGIVRVYGLRDVMFGEMVEFPENTYGLAFNLERDSVGAVVMGPYEHLEEGMTARCTGRILEVPVGEALLGRVVDGLGKPIDGKGPIDTSETSPIEKVAPGVITRKSVDTSLPTGLKSIDAMVPIGRGQRELIIGDRQTGKTAIAIDTIINQKHTGVKCIYVAIGQKQSSVAAVVRKLEEHGAMEHTIVVNASASEAAALQYLAPYAGCTMGEYFRDRGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDIFYLHSRLLERAAHVNEAYVKEFTKGKVTGKTGSLTALPIIETQAGDVSAFIPTNVISITDGQIYLDVNLFNAGIRPAINAGLSVSRVGGAAQTKIIKKLIGGLRIALAQYRELEAFSQFASDLDEATRKQLEHGQRVMEILKQPQYQPLSVGEMAIIWYVVNNNYLDQVELKKVVDFERSLLSFLRDQHQDLLDEINKNPNYSEKIIEKIKAVVEEFVKTQSY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ADDA_BACHK
Sequence: MIENWPKKPEGSQWTDDQWKAVVANGRDILVAAAAGSGKTAVLVERIIKKIINEENPVDVDRLLVVTFTNAAAQEMKNRIGEALEKVLIDEPGSQHIRKQLSLLNKASISTIHSFCLQVIRGYYYMLDVDPRFRIANQTENELLKEEVLDDILEEEYGIEDNTIFFELVDRYTSDRSDDDLQRMILALHTESRAHPNPEKWLDKLVEAYDVEGKTIEDLVYASYLLEDVKFQLETAEQHIRKATELAMLPDGPAPRVETLQADLALLGTLSSAARESWTSVYEAMQNVSWQTLKRIKKSDYNEDIVKQVDSLRNKAKDEVKKLQEELFSRRPESFLRDFQDMHPVLEKLVQLVKVFTERFQAMKRDKGMVDFTDLEHFCLQILSEQSEDGEMKPSAVALQYRNKFAEVLVDEYQDTNFVQESIIKFVTKDSESEGNLFMVGDVKQSIYRFRLAEPGLFLGKYKRFTQEGLGGGMKIDLAKNFRSRHEVLAGTNFIFKQIMGEEVGEIDYDADAELKLGATYPEGEDVAAELLCIQQTEEEVIDGEEGAEVEKAQLEARLMAQRIKAMVDSGYEVYDRKTDSMRPVQYRDFVILLRSMPWAPQIMEELKLQGIPVYADLATGYFEATEVNIMMNVFRVIDNPMQDIPLAAVLRSPIVGLNDEELATLRAHGKKGSFYEVMSSFLKGAPLEEEKELHDKLEWFYNLLQGWREFARQQSLSDLIWKVYGETGYYDFVGGLPAGKQRQANLRVLYDRARQYEATSFRGLFRFLRFIERILERGDDMGTARALGEQEDVVRIMTIHKSKGLEFPVVFVAGLGRRFNTQDLMKRFLLHKDFGFGSQFIDPRKRIKYTTLSQLAIKRKMKMELIAEEMRVLYVALTRAKEKLILIGTVKDANKEMEKWLDAREYSEWLLPDHIRAGASCYLDWIAPSLYRHRDSEMLLELGQGSIPDEIYGYDTSWKVEVVDGNTLLAPEPVQEEKQELLEALREKKAVPLQSERKDEVYDRLMWKYGYEEATSHRAKQSVTEIKRNYQSEEGSDNAFIKKLRAPIQTRPRFMEKKGLTYAERGTAVHAVMQHVDLKKPITVEVLQEQIAGMVNKELLTFEQAEEIAVEKVISFFDSDLGKRVLAAKSVEREVPFTMMLAAEEAYQDWQGKSGESILVQGVIDCMIEEEDGITLIDFKTDTIEGKFPGGFEQAKPILEERYKVQLSLYAKALEKSLQHPVKEKCLYFFDGNHVIKVEE
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: K2C72_HUMAN
Sequence: MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLALSAAARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFGASSSYSYKTAAADVKTKGSCGSELKDPLAKTSGSSCATKKASR
What is the function of this protein?
Has a role in hair formation.  Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable).
What are the official names of this protein?
Keratin, type II cytoskeletal 72, Cytokeratin-72, CK-72, Keratin-72, K72, Type II inner root sheath-specific keratin-K6irs2, Type-II keratin Kb35.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: WDR83_XENLA
Sequence: MSFPAPKPKAPELPQKLQHKLECNQGAVRAVRFNVDGNYCMTCGSDKSLKLWNPHKGSLLKTYSGHGYEVLDTAGSCDNSQLCSCSSDKTVILWDVAQGQVVRKFRGHAGKVNCVQFNEEATVIISGSIDSSIRCWDCRSRRPDAIQIMDEAKDGISSVKVSAHEILAGSVDGNLRRYDLRKGEMCADYLGSPITCVSFSQDSQCLLASSLDSTLRLLDKDTGELLGEYTGHQNLSYKLDSCLSEKDTHVLSCSEDGTVCFWDLVEGSLVLKLPVGKAVVQSLSFHPTECCLLTASEGGVQVWRGASYEEEGGS
What is the function of this protein?
Molecular scaffold protein for various multimeric protein complexes.  Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists.  Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha (By similarity).
What are the official names of this protein?
WD repeat domain-containing protein 83, Mitogen-activated protein kinase organizer 1, MAPK organizer 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat MORG1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSC_SALPC
Sequence: MALHDENVVWHSHPVTVAAREQLHGHRGVVLWFTGLSGSGKSTVAGALEEALHHRGVSTYLLDGDNVRHGLCRDLGFSDADRQENIRRVGEVASLMADAGLIVLTAFISPHRAERQLVKERVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFTGIDAIYEAPDSPQVHLNGEQLVTNLVSQLLDLLRRRDIIRS
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: COBS_GEODF
Sequence: MLRLYFVALQFLAIIPIPFSFRCREEDLGRSMSFFPLVGLTLGLLLAGCDYLLALALPRPVADLLLVAILALVTGALHLDGLADVCDGLAARGGRERFLAVMKDSRVGAVGVVGLVLALLLKYQALFAVTTDKWETLLFFPMVARFSQVQLTVGSKRARQDGLGSLFIGGAGSMQVAVAAFFTVVTGWLLLGLPGIGCAAVCSLFTCLAKAWFHRKLGGITGDAIGCVSELNEILCLMTLVAIGGRF
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL14_CAUSK
Sequence: MIQMQTNLEVADNSGARRVMCIKVLGGAGRRYASVGDVIVVSVKEAIPRGRVKKGDVLRAVVVRVNQGMKRKDGSLIRFDKNAAVIVNKQSEPVGTRIFGPVPRELRAKNHMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: TPS2_CAEEL
Sequence: MGSEPPPSEKKVREPFSRAMKDVQISDEQRLKELWHLLDLLEIEYKKTADLHTLISSVSESLTMVWKRRDPKSELALKGLLLILEYCLSHVFDGHAVFEIFVSSLGFNTVIFWKHCAGYIFDSDLGRGTKFRDALLFSLTLYDVNTGKNRLRELYAAVPGIRKSLLGVNAKQFGERYHHLQKRLARYGSHTSLCSVSSDSEGEEAIHNVRSGTHTESESEEDPKAPRSGLATSHFQQRVINVSNAPPVSLKREKTGDWEIKQGSGGLVACVDPVMSKDHENLWLANLGMNINDKKQKRPGSVASIPESFPSTNTLGLPLIKQTIAEVFFHVLADDDMDAPKNEKQKKAREEMSLLGVLNNYNRGNYKLNPVVVQEDDYNVYYGGISNGLLWPALHNLPEYIVSEYDDEKILRAHWCAYVRVNYQFAIDAVRNSRPQDFIWIHDYHLMLVGMIMQSLDQHLEVGFFLHIPFQPPGEFFSKYSTVGFAVLRGLLRFTKVGFQTHRDRTKYIELVQHYFGTAKIVYDNKMDIYSITNEGWTCSLGVFPVSIKNDDFLKFVDLPETIKLKNDLRKRVMGDTPAPDGRFFFSVERFDYTKGIMEKLQAYKRYFERHPDRIGKDVLFQIAVTNRRSVDTYRVYQDECIDLADKINEIFKDPNNPTWKPLVFQTDGLPRSELVAAYLAMDIGVVTPKKDGMNLVAKEMLVCNPKAGLVLSTGAGSEIQFTTAGLYSDKEKNYHRISNVFDPDSYCDAFYSAALEPEDVRAEHGKRLHEFIMANDIERWSCAFLDPSWTHEVIRPTQVETLDDFFSLMMKTRNVRRQIVGRVLKGIPIRSHFAISLRNAKESLEQICKPGTHTAEFKSGPDSKEVAHFEIDNELQEFERDLSFIDYVQSDDADNVEQFVDTLISSHPISVETYKKEVENAVELLYSADHFHYFFTDRDGTLKSYSCSYPSSIQPAYSGVIQAQFARRCAQTCVILTTAPLMHIGVLDVSTIPNGYYYFGASGGREWFIDNGHNFKDESILKGEKADVLASAYTRISHLLEEPEFRPFTWVGSGLQKHYGHLTIAFQDVYKTITEAQGKQLHEEIEKIVKDVDPHGTRLQLASTEFDIKVYMKTETDGHVFDKGDGLRLLCEKMHCDLTEGNVLVCGDSSTDIPMLKECLIRNPKGVYTIWVTVNDKLKEEVRALCASYSNSNVAFVSCPEVLLGAMAQATIREITITRTRKMSRNIV
What is the function of this protein?
Catalyzes the production of trehalose from glucose-6-phosphate and UDP-alpha-D-glucose in a 2 step process.
What are the official names of this protein?
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 2, Trehalose-6-phosphate synthase 2, UDP-glucose-glucosephosphate glucosyltransferase 2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the gob-1 trehalose phosphatase family.
Protein: TRPB_ALKCK
Sequence: MQETIPDSRGRFGEFGGKYVPETLMSAIEELEAGLAKAMVDPAFIGELKADLAEYAGRETPLTFAKNISAKLGGANIYLKREDLVHTGAHKLNNAIGQGLLAKRMGKNKLVAETGAGQHGVATATVASRLGMECKVFMGVEDMKRQELNVFRMELLGAEVVPAETGSRTLKDATNEAIRYWVSHADDTFYLIGSVVGPHPYPKMVRNFQRVIGDEAKQQMAEKTGRLPDTIVACVGGGSNAIGMFYPFLDDEVELVGVEAAGRGLDTAEHAATISKGSKGIIHGSLTYLLQDESGQIKEPYSISAGLDYPGVGPEHAYLAAQKRVRYEAVTDKEALDALALLAKEEGIIPAIESAHALAKAFQMAKTMTPNQSVLVCLSGRGDKDMHTLQRVYKEGYDE
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: LPXK_LEPBA
Sequence: MKFFFILFYPLSLLYQFLFWVSQFKIKPFVLPHVLVISVGNVTMGGTGKTPFVQYLVRYFKAKNKKYAITILSRGYKAKLSKVGAILRDGLSPHLYGDEPSEHKELFPDVQVIIGKNRKESFLKHNQIHSKFHIVILDDGFQHKQIHRDFDIVLLDANGPFGNGQTIPLGFLREPISHLRRAHTIVFTKLTDQNKDKSIRAINILKQKQIPVPSYTSHFLANLVQIDLNTLKSNPVQLPVDQIRQTKVLDEDANDGYFLFTGVGNPKHVLETAESIIGKKINQHRFFPDHYEFEESVLGSIIGEVKQGTVLLTTEKDWVKVRTKKGFLEELKKRNIQIFVIKIEVVVNEKESFESMLAGLVSTYEAKNDLVSMN
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: URE3_SYNP2
Sequence: MQLSPQEKDKLLIFTAFLVAERRKNKGLKLNYPEAVAYISGLILEGAREGKLVAELMSEGQTWLTRDDVMAGVAEMVDEVQVEATFPDGTKLVTIHNPIQ
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_RENSM
Sequence: MSNAEIFAASGEGVNPIVPNIWDTALVLIGFAILLFIVIKFVVPMFEKTFAERTEAIEGGIAKAEEAQAEATAALEEYKQQLAEARAEANKIREDARAEGAQILADLKEKAASESARITEQAQVAIAAERQAAVVSLRSEVGSLATTLAGRIVGESLQDDARSNRVVDRFLADLEANSKSEGAAK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: TRYT_DROME
Sequence: MHRLVVLLVCLAVGSACAGTVGVSNGDPFEREGRIVGGEDTTIGAHPYQVSLQTKSGSHFCGGSLINEDTVVTAAHCLVGRKVSKVFVRLGSTLYNEGGIVVAVRELAYNEDYNSKTMEYDVGILKLDEKVKETENIRYIELATETPPTGTTAVVTGWGSKCYFWCMTLPKTLQEVYVNIVDWKTCASDEYKYGEIIYDSMVCAYEKKKDACQGDSGGPLAVGNTLVGIVSWGYACASNLLPGVYSDVPALRKWILNASETL
What are the official names of this protein?
Trypsin theta.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: ISPE_METC4
Sequence: MSVLTTRAPAKINLTLHILGRRPGDGYHALESLVAFADVADTLELVPGPDLTLDISGPTAGPAGPLDDNLVLRAARHLAAGVDGLRLGAFRLHKQLPVAAGIGGGSSDAAAALRLLAELNGLALDHPAVIAAARATGADVPVCLDPRARMMRGAGEEIGPVLGLASLPAVLVNPGVPVSTAPVFKALGLAVGQRLDGAELPVVGASLNADAVLAVITPARNDLEAPALTVAPVIGEALALLRAQAGCRLARMSGSGATVFAIFSDDGAAETAAAAIRTAEPGWWVEPTRLA
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: MNME_MYCGE
Sequence: MKSEINIFALATAPFNSALHIIRFSGPDVYEILNKITNKKITRKGMQIQRTWIVDENNKRIDDVLLFKFVSPNSYTGEDLIEISCHGNMLIVNEICALLLKKGGVYAKPGEFTQRSFLNGKMSLQQASAVNKLILSPNLLVKDIVLNNLAGEMDQQLEQIAQQVNQLVMQMEVNIDYPEYLDEQVELSTLNNKVKLIIEKLKRIIENSKQLKKLHDPFKIAIIGETNVGKSSLLNALLNQDKAIVSNIKGSTRDVVEGDFNLNGYLIKILDTAGIRKHKSGLEKAGIKKSFESIKQANLVIYLLDATHPKKDLELISFFKKNKKDFFVFYNKKDLITNKFENSISAKQKDIKELVDLLTKYINEFYKKIDQKIYLIENWQQILIEKIKEQLEQFLKQQKKYLFFDVLVTHLREAQQDILKLLGKDVGFDLVNEIFNNFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_OPISI
Sequence: MGLRKLSIANVDLKDKRVLMRVDFNVPMKDGKVTNTQRIVGASPTIKYALDKGAKSIVLMSHLGGRVGNKVARYSLNPVGEEVSKLLGKPVKFLPDCVGPETTEGMCQSSAGSVFLLENLRFHVEEEGKGVSPTGEKIKATPEQVKAFSENLTKLGDVYLNDAFGTAHRAHASMVGCRLTQRACGFLMDKELTYFSKLLDQPQHPFLAIIGGAKVSDKIQLIKNMLDKVDELIITGGMAFTFLKKLHNMKIGKSLYDEPGAAIVDEWMQLAKSKNVKIHLPVDFITGDKFAEDANTGTATVEPGIRDTHMGLDGGPKTMEEFCKVISRAKTIVWNGPMGVFEMEKFAGGTKAAMDAVVAATTKGVTNNNGGGDTATCCPKWKTEAQVSHVSTGVGASLELLEGKQLPGILALSDA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPXM2_HUMAN
Sequence: MSRPGTATPALALVLLAVTLAGVGAQGAALEDPDYYGQEIWSREPYYARPEPELETFSPPLPAGPGEEWERRPQEPRPPKRATKPKKAPKREKSAPEPPPPGKHSNKKVMRTKSSEKAANDDHSVRVAREDVRESCPPLGLETLKITDFQLHASTVKRYGLGAHRGRLNIQAGINENDFYDGAWCAGRNDLQQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNGSGDMIFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPDPNNYYHRRNEMTTTDDLDFKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHYIAGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDGYEKAYEGGSELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVPNHYIAIPEWFLSENATVAAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDLVRSPWKTQEHTPTPDDHVFRWLAYSYASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLNDFSYLHTNCFELSIYVGCDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAIISVEGINHDIRTANDGDYWRLLNPGEYVVTAKAEGFTASTKNCMVGYDMGATRCDFTLSKTNMARIREIMEKFGKQPVSLPARRLKLRGQKRRQRG
What is the function of this protein?
May be involved in cell-cell interactions.
What are the official names of this protein?
Inactive carboxypeptidase-like protein X2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y3392_CHESB
Sequence: MLKWILILLIVAAVAGLLGMHSLAGAAMTGAKILIAIVLILFLLAVLGIIAIA
What are the official names of this protein?
UPF0391 membrane protein Meso_3392.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SPNF_DROME
Sequence: MEASAAKITPMASSMSASGSTNSPSSEKMNYALQVALQTIKERCIQLQRRVASMEEENQQLREASSRSEGAPRANEIGVTGDVLSLKAQVSELQRQKEQLEEHIGMVSNENRRLWSRLSQISKDQQLNALPSSTDSRAQQNQNLVRSKTFTQHSPNPHLRQKMLSDGIKDLSLEEIALDDFGASSEELGYPYNLQKVEETTSEPDANVDAKRCLDGLQELRREAMKQQQELRSVMTLLENRIALKPCPECAQKTIKKPEMADKSLETDDSLTSELKNYESQHNGHNGTPPSQRINIIQEKIKADAADAMEKTCPMCGKQYSSQVSFNAFREHVEMHFIDDALELESENSIERQFEFVSHAVGDF
What is the function of this protein?
Plays a role in oocyte axis determination and microtubule organization during oogenesis (PubMed:16540510, PubMed:24019068).  Also required for polarized organization of the bristle (PubMed:19917727).  Required, with jvl, for activation of the kinase IKKepsilon in the germ line (PubMed:24019068).  Also required for localization of IKKepsilon to the distal tip of elongating bristles by acting as an adapter linking IKKepsilon and cytoplasmic dynein (PubMed:26092846).  Involved in dendrite pruning in larval sensory neurons during metamorphosis (PubMed:26540204).
What are the official names of this protein?
Protein spindle-F.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm. Cell projection, axon. Cell projection, dendrite. Perikaryon. Note=Localizes to the minus ends of microtubules in oocytes (PubMed:16540510). Found in a punctate pattern colocalized with IKKepsilon in nurse cells (PubMed:16540510, PubMed:18796167). Displays a punctate pattern in the soma, dendrites and axons of larval C4da neurons but becomes dispersed in pupal neurons which is necessary for dendrite pruning (PubMed:26540204).
Protein: ARSC_STAAB
Sequence: MTKKTIYFICTGNSCRSQMAEGWAKQILAEDWNVYSAGIETHGVNPKAIEAMKEVGIDISNHTSDLIDNNIIKNSNLVVTLCSDADVNCPSLPANVKKEHWGFDNPAGKPWSEFQRVRDEIKIAIENFKSR
What is the function of this protein?
Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
What are the official names of this protein?
Arsenate reductase.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_THENN
Sequence: MWSDPIADMLTRIRNANMVFKEYTDIPASNLKRKICEILKREGFIADYKYIEDGKQGILRVYLKYKGGRKNRERVIHGIVRVSHAGRRVYVDKDHIPKVKNGLGIAILTTSKGVLTDKEARQLGVGGEVIAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: KDUI_SHISS
Sequence: MDVRQSIHSAHAKTLDTQGLRNEFLVEKVFVADEYTMVYSHIDRIIVGGIMPITKTVSVGGEVGKQLGVSYFLERRELGVINIGGAGTITVDGQCYEIGHRDALYVGKGAKEVVFASIDTATPAKFYYNCAPAHTTYPTKKVTPDEVSPVTLGDNLTSNRRTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYFYFNMDDDACVFHMMGQPQETRHIVMHNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVKDLR
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase, DKI isomerase.
What is the protein family that this protein belongs to?
Belongs to the KduI family.