PharMolix/UniProtQA huggingface dataset:
Protein: SYFA_LEPBL
Sequence: MNLSEELDSIYQEAIQKIGSSISEEDLDKNKNDFIGKKGKLTAVLKNVALLSIEEKKTIGQKANELSKKLENFVVETKSSLKKKLFETQAASEFFDSLRPLPNASNGSLHPITQIQYEIEDIFTSMGFSIMDGPEIETDTNNFGALNFTDDHPAREMQDTFYLENGNLLRTHTSAIQVRTLRKLKPPFRIIAPGRVFRYEEVDASHEHTFYQIEGMVVGKDISAANLIDTMQVLLSRIFEKEIKTRLRPGYFPFVEPGFELDINCLVCEGKGCPVCKQSGWLELLPCGLIHPNVLSHAGLDPKEWTGFAFGLGLDRLVMMRYGIHDIRYFQSGNLRFLKQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_MARMS
Sequence: MTVQTVKILSELVSTPVDKLLAQMKDAGLPQTSASQEVSEVEKQVLLSYLKRQHGEEGDNSQRITLQRKTTSTLSRDGGKAVNVAVKKKRTYVKRDDEEAQKQEELAKRLAEEQERLAQEKARLELERKQEEEKAAKAKAEAEEKARQEAAVKNVVADAGAVNETEQYVSDTGAAEPVESPKQPKASKKVSQPAMDSKKSTVAPKGKKGPVRHDNDKDKDKPRGRVNPDNKRTSRVNVNDEDEFTRRGKLGRKNKKPSKQEHGFQKPTAKMIHEVALPESITVADLAEKMAVKGAEVIKIMFKMGAMATINQTIDRDTATLVVEEMGHTVKFIDENAVENDMIEAIDYQGEAIKRAPVVTVMGHVDHGKTSLLDYIRTTRVAAGESGGITQHIGAYHVETPHGMISFLDTPGHAAFTSMRARGAKATDIVILVCAADDGVMPQTIEAIQHARAAGVPMVVAMTKIDKEGADIDRVKNELVAQEVVPEEWGGDIQFVGVSAKSGEGIEALLEAVLLQAEVLELTAVPSAPAKGVVVEARLDRGRGSVATLLVQNGTLKKGDIVLAGLQMGRVRALLDETGKAIDSAGPSIPVEILGLDGTPEAGEEFIVVADERKAREVANFRQGKYREVRFARQHSAKLENLFSEMGKDEVRTLNVVLKADVRGSLEALIKSLTDMNTDEVKVNVVSSGVGGITETDATLALASDAVIFGFNVRADNSAKQFIERESIDLRYYSVIYNIIDDVKSALSGMLSPDLREDIKGTAEVRDVFRSPKFGLIAGCMVIEGTVYRNKQIRVLRDDVVIYEGELESLRRFKDAVNEVSRGMECGIGVKNYNDVKVGDKIEVFETVEVARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHF12_HUMAN
Sequence: MWEKMETKTIVYDLDTSGGLMEQIQALLAPPKTDEAEKRSRKPEKEPRRSGRATNHDSCDSCKEGGDLLCCDHCPAAFHLQCCNPPLSEEMLPPGEWMCHRCTVRRKKREQKKELGHVNGLVDKSGKRTTSPSSDTDLLDRSASKTELKAIAHARILERRASRPGTPTSSASTETPTSEQNDVDEDIIDVDEEPVAAEPDYVQPQLRRPFELLIAAAMERNPTQFQLPNELTCTTALPGSSKRRRKEETTGKNVKKTQHELDHNGLVPLPVKVCFTCNRSCRVAPLIQCDYCPLLFHMDCLEPPLTAMPLGRWMCPNHIEHVVLNQKNMTLSNRCQVFDRFQDTVSQHVVKVDFLNRIHKKHPPNRRVLQSVKRRSLKVPDAIKSQYQFPPPLIAPAAIRDGELICNGIPEESQMHLLNSEHLATQAEQQEWLCSVVALQCSILKHLSAKQMPSHWDSEQTEKADIKPVIVTDSSVTTSLQTADKTPTPSHYPLSCPSGISTQNSLSCSPPHQSPALEDIGCSSCAEKSKKTPCGTANGPVNTEVKANGPHLYSSPTDSTDPRRLPGANTPLPGLSHRQGWPRPLTPPAAGGLQNHTVGIIVKTENATGPSSCPQRSLVPVPSLPPSIPSSCASIENTSTLQRKTVQSQIGPPLTDSRPLGSPPNATRVLTPPQAAGDGILATTANQRFSSPAPSSDGKVSPGTLSIGSALTVPSFPANSTAMVDLTNSLRAFMDVNGEIEINMLDEKLIKFLALQRIHQLFPSRVQPSPGSVGTHQLASGGHHIEVQRKEVQARAVFYPLLGLGGAVNMCYRTLYIGTGADMDVCLTNYGHCNYVSGKHACIFYDENTKHYELLNYSEHGTTVDNVLYSCDFSEKTPPTPPSSIVAKVQSVIRRRRHQKQDEEPSEEAAMMSSQAQGPQRRPCNCKASSSSLIGGSGAGWEGTALLHHGSYIKLGCLQFVFSITEFATKQPKGDASLLQDGVLAEKLSLKPHQGPVLRSNSVP
What is the function of this protein?
Acts as a transcriptional repressor.  Involved in recruitment of functional SIN3A complexes to DNA.  Represses transcription at least in part through the activity of an associated histone deacetylase (HDAC).  May also repress transcription in a SIN3A-independent manner through recruitment of functional TLE5 complexes to DNA.
What are the official names of this protein?
PHD finger protein 12, PHD factor 1, Pf1.
What are the subcellular locations of this protein?
Nucleus.
Protein: LCK6_RHYMA
Sequence: QSSFHSWG
What is the function of this protein?
This cephalomyotropic peptide stimulates contractile activity of cockroach protodeum (hindgut).
What are the official names of this protein?
Leucokinin-6, Leucokinin VI, L-VI.
What are the subcellular locations of this protein?
Secreted.
Protein: SCK6_MESMA
Sequence: LPYPVNCKTECECVMCGLGIICKQCYYQQ
What are the official names of this protein?
Neurotoxin BmK A3-6.
What are the subcellular locations of this protein?
Secreted.
Protein: RL27_STRZJ
Sequence: MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTGGSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: HIS61_PARMW
Sequence: MVALRLIPCLDVARGRVVKGVNFVGLRDAGDPVELACRYSGAGADELVFLDIAASHEGRGTLIDMVHRTAESVTIPFTVGGGISTVEGITDLLRAGADKVSLNSSAVRRPELVREGAERFGCQCIVVAIDARRRDGDGWDVFVKGGRENTGLDAVDWARRVAELGAGEILLTSMDGDGTQAGYDLALTRAVADAVPVPVIASGGAGCIDHIAQALETGPDGGHASAALLASLLHDGVLTVEEIKQDLLARGLSIRP
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit hisF1, IGP synthase cyclase subunit, IGP synthase subunit hisF1, ImGP synthase subunit hisF1, IGPS subunit hisF1.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYC_TRYBB
Sequence: AALPPGDAAAAQGGSNGVGPNLYGIVGRKSGTVEGFTYSKANQDSGVMWTPQVLDVYLENPKKFMPGTKMSFAGLKKPQERADLIAYLETLKD
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: RLMN_AGRVS
Sequence: MAATEIIIERTPQARPAAMTGATKPTLIGQTREEMGEMLREIGVADKQVRMRVAQLWNWIYVRGVSDFDQMTNVAKDMREKLKAHFTIARPEIVEEQVSNDGTRKWLLRYPPRGAGRPVEVECVYIPEEGRGTLCVSSQVGCTLTCTFCHTGTQKLVRNLTAEEVLSQLLLARDRLGDFPDRDAPVGAMVPNEGRKITNMVMMGMGEPLYNFEEVKKALLIASDGDGLSLSKRRITLSTSGVVPEIYRTGDEIGVMLAISLHAVRDELRDLLVPINKKYPLKDLIEACRNYPGLSNARRITFEYVMLKDVNDSLEDAKGLIQLLKGIPSKINLIPFNPWPGTNYQCSDWDQIMKFADFINSAGYASPIRTPRGRDILAACGQLKSESERMRKTERLAYEAMMIVGHGEDD
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHY1_SCHPO
Sequence: METNGSFSGARLVDGKWIIPESRRKDGSVRRERAVKPGYTAPEDIKRYRPGRGNFASLEKQMKKLQLSNDASTSKSIDRPPISELEKEKLERPLSNKKKEKNDHKAESLKHDYDSVGEKRISKDSVKHLDKTYSSIDSKKDFKYNFPKTQAPEWRRGAKPLSKTSEPSVYSEKMSKRENKKSINTVDKKTGYKEKE
What are the official names of this protein?
Uncharacterized protein C19C7.01.
Protein: GLHA_MACFA
Sequence: MDYYRKYAAVILVTLSVFLHILHSFPDGEFTMQDCPECKPRENKFFSKPGAPIYQCMGCCFSRAYPTPLRSKKTMLVQKNVTSESTCCVAKSLTRVMVMGNVRVENHTQCHCSTCYYHKF
What is the function of this protein?
Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG.  These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
What are the official names of this protein?
Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Choriogonadotropin alpha chain, Chorionic gonadotrophin subunit alpha, CG-alpha, Follicle-stimulating hormone alpha chain, FSH-alpha, Follitropin alpha chain, Luteinizing hormone alpha chain, LSH-alpha, Lutropin alpha chain, Thyroid-stimulating hormone alpha chain, TSH-alpha, Thyrotropin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit alpha family.
What are the subcellular locations of this protein?
Secreted.
Protein: C556_AGRFC
Sequence: MCMKLKTITAAMLFGCLCAGAVYAAGEVEKREGMMKQIGGSMGALAAISKGEKPFDAAAVKAAVTTISTNAKAFPDQFPVGSETGSAAAPAIWENFDDFKAKAAKLGTDADAVLANLPTDQAGVATAMKTLGADCGTCHQTYRLKK
What is the function of this protein?
Low-spin monoheme cytochrome c.
What are the official names of this protein?
Cytochrome c-556, Cytochrome c556.
Protein: RF2A_ORYSJ
Sequence: MNREKSPIPGDGGDGLPPQATRRAGPPAAAAAAEYDISRMPDFPTRNPGHRRAHSEILSLPEDLDLCAAGGGDGPSLSDENDEELFSMFLDVEKLNSTCGASSEAEAESSSAGAAAAVAAAAAAAAHGARPKHQHSLSMDESMSIKAEELVGASPGTEGMSSAEAKKAVSAAKLAELALVDPKRAKRIWANRQSAARSKERKMRYIAELERKVQTLQTEATTLSAQLALLQRDTSGLTTENSELKLRLQTMEQQVHLQDALNDTLKSEVQRLKVATGQMANGGGMMMNFGGMPHQFGGNQQMFQNNQAMQSMLAAHQLQQLQLHPQAQQQQVLHPQHQQQQPLHPLQAQQLQQAARDLKMKSPMGGQSQWGDGKSGSSGN
What is the function of this protein?
Transcription factor probably involved in vascular development and shoot tissue organization.  Binds to the DNA sequence 5'-CCGAGTGTGCCCCTGG-3' present in the promoter region Box II of the phloem-specific rice tungro bacilliform virus (RTBV) promoter.  May regulate tissue-specific expression of the RTBV promoter and virus replication.
What are the official names of this protein?
Transcription factor RF2a.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
Protein: T23O_DROER
Sequence: MSCPYAGNGNDHDDSAVPLTTEVGKIYGEYLMLDKLLDAQCMLSEEDKRPVHDEHLFIITHQAYELWFKQIIFEFDSIRDMLDAEVIDETKTLEIVKRLNRVVLILKLLVDQVPILETMTPLDFMDFRKYLAPASGFQSLQFRLIENKLGVLTEQRVRYNQKYSDVFSDEEARNSIRNSEKDPSLLELVQRWLERTPGLEESGFNFWAKFQESVDRFLEAQVQSAMMEPVEKAKNYRLMDIEKRREVYRSIFDPAVHDALVRRGDRRFSHRALQGAIMITFYRDEPRFSQPHQLLTLLMDIDSLITKWRYNHVIMVQRMIGSQQLGTGGSSGYQYLRSTLSDRYKVFLDLFNLSTFLIPREAIPPLDETIRRKLVHKSV
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Protein vermilion, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: KTHY_EXISA
Sequence: MSGMFITVEGPDGSGKSTQLQLLVENLKQKGYDIVVTREPGGTTVGNQIREVLLSPDHHEMTPRVEMMLYAASRAQNVEQVIRPALERGAIVLCDRFIDASIAYQGYGLQYDLDQIRSLNEWATNGLTPDLTFLFDLNPERASARMKDRGQLDRIESRDQAFHERVYAGFQTLLKQYPERIVRIDADQSIECIQDEVLDYTIERLQQGGVQK
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: KN5D_ARATH
Sequence: MDSIQQRRGGIVSLSPAQTPRSSDKSARESRSSESNSTNRNDKEKGVNVQVILRCRPLSEDEARIHTPVVISCNENRREVAATQSIAGKHIDRHFAFDKVFGPASQQKDLYDQAICPIVFEVLEGYNCTIFAYGQTGTGKTYTMEGGARKKNGEFPSDAGVIPRAVKQIFDILEAQGAEYSMKVTFLELYNEEISDLLAPEETIKFVDEKSKKSIALMEDGKGSVFVRGLEEEIVSTANEIYKILEKGSAKRRTAETLLNKQSSRSHSIFSITIHIKENTPEGEEMIKCGKLNLVDLAGSENISRSGAREGRAREAGEINKSLLTLGRVINALVEHSGHIPYRDSKLTRLLRESLGGKTKTCVIATISPSIHCLEETLSTLDYAHRAKNIKNKPEINQKMMKSAVMKDLYSEIDRLKQEVYAAREKNGIYIPKDRYIQEEAEKKAMAEKIERLELQSESKDKRVVDLQELYNSQQILTAELSEKLEKTEKKLEETEHSLFDLEEKYRQANATIKEKEFVISNLLKSEKSLVERAFQLRTELESASSDVSNLFSKIERKDKIEDGNRFLIQKFQSQLTQQLELLHKTVASSVTQQEVQLKHMEEDMESFVSTKSEATEELRDRLSKLKRVYGSGIEALDNIAVKLDGNSQSTFSSLNSEVSKHSHELENVFKGFASEADMLLQDLQSSLNKQEEKLITFAQQQRKAHSRAVDTARSVSKVTVEFFKTLDTHATKLTGIVEEAQTVNHKKLSEFENKFEECAANEERQLLEKVAELLANSNARKKNLVQMAVHDLRESASTRTTTLQHEMSTMQDSTSSIKAEWSIHMEKTESSHHEDTSAVESGKKAMQEVLLNCLEKTEMSAHQWRKAQESLVSLERNNVASVDSIVRGGMDANENLRSQFSTAVSSSLDVFDAANSSLLTSIDHSLQLDNDACTKVNSMIIPCCEDLIELKSDHNHKIIEITENAGKCLLDEYVVDEPSCSTPKKRPIDIPSIESIEELRTPASEELLRAFRDEKLSKQANGDAKQQQQQQQQHLIRASSLYEAAVSDSRYPLSAVN
What is the function of this protein?
Responsible for microtubule translocation.  May be important for the organization of phragmoplast-specific arrays of microtubules (By similarity).  Plays an essential role in stabilizing the mitotic spindle.  Required during mitotic cytokinesis (By similarity).
What are the official names of this protein?
Kinesin-like protein KIN-5D.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-5/BimC subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Note=Microtubule-associated.
Protein: CLPS_RUEST
Sequence: MLMQPLMMSDNPDDESDLGLLTKTRPRTQRPPRYKVLLLNDDYTPMEFVVIVLERFFGLNHAQAFEIMLTVHKKGLAVVGVFSHEVAETKVAQVMDYARRHQHPLQCTMEKDD
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: RM05_SOLTU
Sequence: MDQLMFPLYFHYEDVLRQDLLLKLNYANVMEVPGLCKIIVVPKTAPSIKNGKLAMEISCGQKLKQRASTGKSFRSNPFLGSNKDKKGYVSDLARQSTLRGHGMSHFLVRISTVMSLLDSPLEIRERSIQFSMETEFCEFSPELEDHFEIFEHIRGFNVTIVTSANTQDETLLLWSGFLQKDEGETQ
What are the official names of this protein?
60S ribosomal protein L5, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SRTD4_HUMAN
Sequence: MTLVLSMNRFCEPIVSEGAAEIAGYQTLWEADSYGGPSPPGPAQAPLQGDRGAGPPLAGSHYRGISNPITTSKITYFKRKYVEEEDFHPPLSSCSHKTISIFEERAHILYMSLEKLKFIDDPEVYLRRSVLINNLMKRIHGEIIMQNNWCFPACSFNGTSAQEWFMAQDCPYRKRPRMAKEECEKFHACCFYQECGGHYLNLPLSVNANVGSASTAASSPSASSSSSSSSSSPPLPLPSCSRQVDFDVGSASIYKSDGQIPANEIFVTNVRSLGVQEKAKLNDEKANDDTNRDGGPLSHEPVGNDLAFECKGQFYDYFETGYNERNNVNESWKKSLRKKEASPPSNKLCCSKGSKI
What are the official names of this protein?
SERTA domain-containing protein 4.
Protein: MOAA_STACT
Sequence: MVKQITDKLGRPIRDLRLSVTDRCNFRCDYCMPKEIFGDDFVFLPKDELLSFSEMERIARVYTHLGVKKIRITGGEPLMRRDLYKLIAALNEIEGVEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDNELFQSINNRNIKADTILEQIDYAVSIGFKVKINVVVQKGVNDDQIIPMVQYFKDKNIQVRFIEFMDVGNDNGWDFSKVVSKDEMLSMIQEEFDIEAVEPKYYGEVAKYYRHKDNGAQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFSTVDGFNVKEFMRSGVSDDELQAKFEELWNIRDDRYSDERTEQTVAIRKRKKINMNYIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: CLPP_MACCJ
Sequence: MNLIPTVIESTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLQAQDAEKDIYLYINSPGGSVTAGMAIYDTMQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAARHILKTREKLNRILAERTGQPIEKIEKDTDRDNFLTADEAKAYGLIDEVMHPAE
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEPD5_HUMAN
Sequence: MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKEDLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRASIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNSTSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFTPRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTTCRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHLHQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINPFAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLELAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTSPDPILTLSAPPVVPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDEDGVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGLVSRNRPEEEDQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSEFVSCWVEFSHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIYGDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGPISTHSLESTAPPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTPTYMDSPRKDGAFFMEFVRSPRTASSAFYPQVSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSSSQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAEVVHWLVNHVEGIQTQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRVAMQQPATTWHTAGVDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMVQGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLLKEGSEHLFDSFEPETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTVFLQLPYSKRKFSGQQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFADRLLKDFTDFCINRDNRLVTFWTSCLEKMHASAP
What is the function of this protein?
As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway.  The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling.  The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.
What are the official names of this protein?
GATOR complex protein DEPDC5, DEP domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the IML1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, perinuclear region. Lysosome membrane. Note=Localization to lysosomes is amino acid-independent.
Protein: ACCD_ACHLI
Sequence: MNHLLDERKRRLSQFHEIIKKRPIETRPVDIPDGVFSQCEQCNSAIYNKDLEHNYEVCPYCSYHFKINAVKRLKYTLDEDTFKPLFENITSKNPLGMPEYEEKLDKGMRMAKMNEAFLAGTGKIDGQNLAIGVLDSYFMMGSMGSVVGERITRLIEHAAKHNLPLVIFSASGGARMQEGILSLMQMAKTSGALNLLDEKGLVYISVMTNPTTGGVAASFASLGDINIAEKSSLIGFAGARVIKQTIGQDLPAGFQTDAFQLQKGQVDLVVLRSQLKKTLSTLLKLHAKKVTS
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSPA_MYCS2
Sequence: MKAISRVLIAMVAAIAALFTSTGTSHAGLDNELSLVDGQDRTLTVQQWDTFLNGVFPLDRNRLTREWFHSGRAKYIVAGPGADEFEGTLELGYQIGFPWSLGVGINFSYTTPNILIDDGDITAPPFGLNSVITPNLFPGVSISADLGNGPGIQEVATFSVDVSGAEGGVAVSNAHGTVTGAAGGVLLRPFARLIASTGDSVTTYGEPWNMN
What is the function of this protein?
The major porin in this organism, forms a water-filled channel which favors the permeation of cations, amino acids, iron Fe(3+) and less efficiently phosphate.  Does not transport Fe-ExoMS, the predominant siderophore.  Plays a role in transport of beta-lactamase and hydrophilic fluoroquinolone antibiotics such as norfloxacin as well as chloramphenicol.  There are about 2400 porins in wild-type, 800 in an mspA deletion and 150 in a double mspA-mspC deletion.  Different conductance values with maxima at 2. 3 and 4. 6 nanosiemens might be caused by a simultaneous reconstitution of MspA channels into the membrane or by the existence of different MspA conformations.
What are the official names of this protein?
Porin MspA.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial porin (TC 1.B.24) family.
What are the subcellular locations of this protein?
Cell outer membrane. Secreted, cell wall.
Protein: NDK_CUPPJ
Sequence: MAIERTLSIIKPDAVAKNVIGQIYARFEAAGLKIVAAKMVHLSRGEAEQFYAVHKERPFFKDLVDFMVSGPVMIQALEGEGAIAKNRDLMGATDPKKADKGTIRADFADSIDANAVHGSDAAETAAVEIAFFFPGMNVYTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_DEIDV
Sequence: MNRIEAHLLATDLKFAIISTRWNHLIVDRLVEGAELAFVQHGGRSENLDHYLSPGAYEVPLIARKLAESGRYDAIVCLGAVIKGDTDHYDFVAGGAANGILNTSLHTGVPVAFGVLTTDTVEQALNRAGIKAGNKGAEATLAMIETVNLLRQIPQS
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: CUSF_ECOL6
Sequence: MKKALQVAMFSLFTVIGFNAQANEHHHETMSEAQPQVISATGVVKGVDLESKKITIHHDPIAAVNWPEMTMRFTITPQTKMSEIKTGDKVAFNFVQQGNLSLLQDIKVSQ
What is the function of this protein?
Part of a cation efflux system that mediates resistance to copper and silver.  Binds one copper per polypeptide (By similarity).
What are the official names of this protein?
Cation efflux system protein CusF.
What are the subcellular locations of this protein?
Periplasm.
Protein: MTNC_SYNP6
Sequence: MPLPVSITTLLLDIEGTTTPVDFVFKVLFPYARDRVADFLATQGADPEVQADLDLLRQEYAQEAAAELPDWAGEDAIAAVPYIQWLIDSDRKSTGLKSLQGKIWEQGYVSGEIKGQLFADVLPAFQRWQAAGLAIAIFSSGSVQAQQLLFGYSEAGDLSPHLSGYFDTRTGPKREAASYGAIAAQLGKAPAQVLFVSDIPAELEAAATAGFQTRLSLRPGNATVEIGDWTTIHSFDEL
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: RL21_SYNSC
Sequence: MADTKPAAEQSGTYAIVEASGTQIWLQPNRYYDIDRLQAEVDDTIKLENVLLVKDGKGTTLGQPYVKDATVSLKVMAHRRGPKVIVYKMRPKKKTRRKNGHRQELTRVMVESISVGGKAIS
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.