PharMolix/UniProtQA huggingface dataset:
Protein: MSCL_PARD8
Sequence: MKKILQEFKQFAMRGNVVDMAVGIIIGGAFGKIVSSIVADLIMPAVGLLVGGVNFTDLKITLKHAVMEGDKVISPAVSINYGNFIQVTLDFIIIAFAVFLLVKGVNALSKKKEEAPKAPVAPPADIQLLTEIRDLLKNNK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CNIH1_ORYSJ
Sequence: MVFVWLTAFFLVVALIVLVIYQLMCLADLEFDYINPFDSSSRINKVVIPEFVLQAALSVLFLLSGHWAMFLLSAPMVYYNYTLYQRRQHLVDVTEIFNHLGREKKRRLFKIVGLIILLFLSLFWMIWTVLLEEDE
What is the function of this protein?
Acts as cargo receptor necessary for the transportation of the cation transporter HKT1;3 and possibly other secretory proteins from the endoplasmic reticulum (ER) in COPII-coated vesicles targeted to the Golgi apparatus.
What are the official names of this protein?
Protein cornichon homolog 1, OsCNIH.
What is the protein family that this protein belongs to?
Belongs to the cornichon family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Located primarily in the endoplasmic reticulum (ER); may cycle between the ER and the Golgi apparatus.
Protein: HELS_SACS9
Sequence: MSLELEWMPIEDLKLPSNVIEIIKKRGIKKLNPPQTEAVKKGLLEGNRLLLTSPTGSGKTLIAEMGIISFLLKNGGKAIYVTPLRALTNEKYLTFKDWELIGFKVAMTSGDYDTDDAWLKNYDIIITTYEKLDSLWRHRPEWLNEVNYFVLDELHYLNDPERGPVVESVTIRAKRRNLLALSATISNYKQIAKWLGAEPVATNWRPVPLIEGVIYPERKKKEYNVIFKDNTTKKVHGDDAIIAYTLDSLSKNGQVLVFRNSRKMAESTALKIANYMNFVSLDENALSEILKQLDDIEEGGSDEKELLKSLISKGVAYHHAGLSKALRDLIEEGFRQRKIKVIVATPTLAAGVNLPARTVIIGDIYRFNKKIAGYYDEIPIMEYKQMSGRAGRPGFDQIGESIVVVRDKEDVDRVFKKYVLSDVEPIESKLGSERAFYTFLLGILSAEGNLSEKQLENFAYESLLAKQLVDVYFDRAIRWLLEHSFIKEEGNTFALTNFGKRVADLYINPFTADIIRKGLEGHKASCELAYLHLLAFTPDGPLVSVGRNEEEELIELLEDLDCELLIEEPYEEDEYSLYINALKVALIMKDWMDEVDEDTILSKYNIGSGDLRNMVETMDWLTYSAYHLSRELKLNEHADKLRILNLRVRDGIKEELLELVQISGVGRKRARLLYNNGIKELGDVVMNPDKVKNLLGQKLGEKVVQEAARLLNRFH
What is the function of this protein?
DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.  A low processivity 3'-5' helicase.  Unwinds short dsDNA substrates with 3'-overhangs (25 bp dsDNA with 25 base overhang), less active on longer dsDNA substrates.  Also unwinds the lagging strand of a stalled replication fork (but the leading strand was not tested).  Binds ssDNA, but dsDNA about 35-fold less well.  Able to displace streptavidin from biotinylated ssDNA, which is partially inhibited by DNA-binding proteins, suggesting it may play a role in stripping proteins from stalled replication forks.
What are the official names of this protein?
ATP-dependent DNA helicase Hel308.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Hel308 subfamily.
Protein: PCR5_ARATH
Sequence: MGRPVGQTNQAQPSVQHTASPSNKVSHNGGIGKPANIPTGIPVNYQQTQNQWSSQLFDCMNDSENAVITLIAPCVTFGQIAEIVDEGATPCATAGLLYGALFFTGASFVYSYMFRARIRKKFGLPDAPAPDWITHLVCMPFALCQEYRELKHHGFDPILGWAGNVQQAQQQEMMTPPTGQRMMG
What is the function of this protein?
May be involved in heavy metals transport.
What are the official names of this protein?
Protein PLANT CADMIUM RESISTANCE 5, AtPCR5.
What is the protein family that this protein belongs to?
Belongs to the cornifelin family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DRS1_MAGO7
Sequence: MAPSSKRKAINDDFITTISDNEADEFVEEEEVIQEEAPPKKKSKTIPKKKQKRSSKKASNDDDAEDEEDGHIEGVWGQNDDDDGAMDSDFEFVTGAGVEDLDDNPEFEGWGFDGAKKAMGQGNGVDLDEIIRRRREKKEGGTKGAAEPEAKAEEEGEALGLDDDDDEVLARDAFGMGAGSDDEDSAEASEGQDGSEASEGEEGDSDDESVASPVPHPDDDQESESEQDEDEEEAAKMKEFFAADEPKSDTNKGNASFQSMSLSRPILRGLTSVGFAKPTPIQSKTIPIALMGKDVVGGAVTGSGKTAAFVVPILERLLYRPKKVPTSRVVILAPTRELAIQCHAVATKLASHTDIKFCLAVGGLSLKVQESELRLRPDVIIATPGRFIDHMRNSASFAVDTVEILVLDEADRMLEDGFADELNEILTTLPKSRQTMLFSATMTSSVDNLIRVGLNKPVRLMVDSQKKTVVTLTQEFVRLRPGREEKRMGYLVYLCKNLYTERVIIFFRQKKIAHHARIIFGLLGLSCAELHGSMSQIQRIQSVEAFRDGKVSFLLATDLASRGLDIKGVDTVINYEAPQSLEIYVHRVGRTARAGRSGTAITLAAEPDRKVVKAAVKAGKAQGAKISSRIIDAADADSWQAKIDELEDEVEAVMREEKEEKVLAQADMEMRKGENMIRYEDDIKARPKRTWFETEKDKKAAREAGRAALNGVREALKKKHGGKNLSNKDKKKLDAMAEAKEARVWKKGAAERAGKGAVLNFKKDKSSKKGPVVGGRVAKKGAPRGKPRRR
What is the function of this protein?
ATP-binding RNA helicase involved in ribosome assembly.
What are the official names of this protein?
ATP-dependent RNA helicase DRS1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX27/DRS1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MNMA_HISS2
Sequence: MKSIVYEKKLPKLTALEIAKNSKKKVICGMSGGVDSSVSAFILQQQGYQVEGLFMKNWEEDDDTDYCTAANDLADAQAVCDKLGIKLHKINFAAEYWDNVFEHFLAEYKAGRTPNPDILCNKEIKFKAFLEYAVEDLGADYIATGHYVRRSDVNGQTKLLRGLDSNKDQSYFLYTLSKDQVAQSLFPVGEIEKPIVRAIAGDLGLITAEKKDSTGICFIGERKFKDFLERFLPAQPGEIRMVDGKVIGKHDGLMYYTLGQRKGLGIGGVKGLSEDPFYVVDKDLINNVLVVAQGNDNSALLSQGLMATQLYWIDRLPIRQNLRCTVKTRYRQKDVACEVIPINDDCIEVRFDEPQIAVTPGQSAVFYQGEVCLGGGVIERQIK
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_STRPQ
Sequence: MTLASQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLSYPKTRDLIENGFVETIRAHFPEVEVIAGTATAGIPHGAIIADKMTLPFAYIRSKPKDHGAGNQIEGRVLKGQKMVIIEDLISTGGSVLDAAAAASREGADVLGVVAIFTYELPKASQNFKEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLKKFKEDQVNWQQ
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: ACP_CAMC5
Sequence: MAVFDDVRDVVVEQLSVDPEAVKMESKIIEDLGADSLDVVELVMALEEKFEVEIPDTEAEKLISIADVVNYIEKLGK
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_BURCH
Sequence: MIRTDAKDGALVLFSGGQDSATCVAWALERYQTVETLGFDYGQRHRVELECREGVREALKHRFPAWSDRLGDDHMIDLSVLGAISDTAMTRTIEIETTANGLPNTFVPGRNLMFMTIAAAIAYRRGLRVLVGGMCETDFSGYPDCRDDTMKALQVALNLGMDTRMVLETPLMWLDKAQTWQLAEQLGGEALVELIRVETHTCYVGERAELHDWGFGCGECPACKLRKRGYEAYLKGERVTEAPL
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: NUDI_SALTI
Sequence: MRQRTIVCPLIQNDGCYLLCKMADNRGVFPGQWALSGGGVEPGERIEEALRREIREELGEQLILSDITPWTFRDDIRVKTYADGRQEEIYMIYLIFDCVSANRDICINDEFQDYAWVKPEELALYDLNVATRHTLALKGLL
What is the function of this protein?
Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP).
What are the official names of this protein?
Nucleoside triphosphatase NudI, Nucleotide diphosphatase NudI, Pyrimidine deoxynucleoside triphosphate diphosphatase, dCTP diphosphatase, dTTP diphosphatase, dUTP diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudI subfamily.
Protein: PAX_I01A0
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESTIVESSDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHTYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLYTIRQEMASRGLWDSFVNPKEAKRQLKKDLKSQELCAGLPTKVSHLISPALKTLEPMWMDSNRTAVLRASFLKCQKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: KHSE_MYCS2
Sequence: MTQTLPVGLSATSVVAASSANLGPGFDSLGIALSLYDEIVVETVESGLTVHVEGEGAGQVPLDQTHLVVRAINKGLQAAGFSAPGLVVRCRNDIPHSRGLGSSAAAVVGGLAAVNGLVTQAGSEPMDDARLIQLSSEFEGHPDNAAAAVLGGAVVSWTEQAGAFGGEPRYSAVPVRLHPDIRLFPAVPQQRSSTAETRVLLPEQVSHVDARFNLSRAALLVVALSERPDLLMAATEDVLHQPQRAAAMPASAEYLAILRRCGIAAVLSGAGPSVLGLSAQSGLPAEALEYGTAHGFTVTEMSVGAGVRWTAGAVVRN
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBD_CHAVU
Sequence: MTIAIGKSSEEPKGIFDTMDDWLRRDRFVFVGWSGLLLFPCAYFSLGGWLTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSMAHSLLLLWGPEAQGDFTRWCQLGGLWTFIALHGAFALIGFMLRQFELARSVQLRPYNAIAFSGPISVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQSEETYSMVTANRFWSQIFGIAFSNKRWLHFFMLFVPVTGLWMSAIGVVGLALNLRAYDFVSQEIRASEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLVFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PTMA_BOVIN
Sequence: MSDAAVDTSSEITTKDLKEKKEVVEEAENGREAPANGNANEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEEDGDEDEEAEAATGKRAAEDDEDDDVDTKKQKTDEDD
What is the function of this protein?
Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.
What are the official names of this protein?
Prothymosin alpha.
What is the protein family that this protein belongs to?
Belongs to the pro/parathymosin family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GET3_ASPFN
Sequence: MSTAVVQADDLMEPSLQSIVSQDTLRWIFVGGKGGVGKTTTSCSLAIQLAKARKSVLLISTDPAHNLSDAFGQKFGKEARLVDGYTNLSAMEIDPNGSIQDLLASGEGQGDDPMAGLGVGNMMQDLAFSIPGVDEAMSFAEVLKQVKSLSYEVIVFDTAPTGHTLRFLQFPTVLEKALAKLSQLSSQFGPMLNSILGSRGGLPGGQNIDELLQKMESLRETISEVNTQFKNPDMTTFVCVCIAEFLSLYETERMIQELTSYNIDTHAIVVNQLLFPKQGSECEQCNARRKMQKKYLEQIEELYEDFNVVRMPLLVEEVRGKEKLEKFSDMLIHPYVPPQ
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
What are the official names of this protein?
ATPase get3, Arsenical pump-driving ATPase, Arsenite-stimulated ATPase, Golgi to ER traffic protein 3, Guided entry of tail-anchored proteins 3.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: ICMT_MOUSE
Sequence: MAAARRGSAGSEARLSLATFLLGASVLALPLLTRAGLQGRTGLALYVAGLNALLLLLYRPPRYQIAIRACFLGFVFGCGVLLSFSQSSWNHFGWYVCSLSLFHYSEYLVTAVNNPKSLSLDSFLLNHSLEYTVAALSSWIEFTLENIFWPELKQITWLSATGLLMVVFGECLRKAAMFTAGSNFNHVVQSEKSDTHTLVTSGVYAWCRHPSYVGWFYWSIGTQVMLCNPICGVVYALTVWRFFRDRTEEEEISLIHFFGEEYLDYKKRVPTGLPFIKGVKVEL
What is the function of this protein?
Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.
What are the official names of this protein?
Protein-S-isoprenylcysteine O-methyltransferase, Isoprenylcysteine carboxylmethyltransferase, Prenylated protein carboxyl methyltransferase, PPMT, Prenylcysteine carboxyl methyltransferase, pcCMT.
What is the protein family that this protein belongs to?
Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: DAPB_HELAH
Sequence: MKIGVYGASGRIGKLLLEELKGGYKGLVLSSVFVRQKCEIDFSSFSHKPLVTNDLKAFVRACECVIDFSLPKGVDSLLDTLLECPKILVSGTTGLEEKTLEKMQNLALKTPLLHAHNMSIGIAILNQLAFLASLKLKDADIEIVETHHNLKKDAPSGTALSLYQTCAKARGYDEKNALTTHREGLRSKESIGVAALRGGDVAGKHTIGFYLEGEYIELSHTATNRSIFAKGALEVALWLKDKAAKKYEINEIFD
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIW4_SCHPO
Sequence: MNNLVKIATHSGTFHADEALAVYMLRRLDRFSGAQIVRSRDPQVLDSCDIIVDVGGKYDGIKYFDHHQREFNDTFSPKYSTRLSSAGLIYKHFGREVIHAVLPQLKINEQDLETLYEKVYQSFVEGLDANDNGISAYPAGLKPSFKAAMSLPEMVSSFLPAWNSEKQDDQTYLECFQKASDLMGTWFVRSVEHYALSWLPAKTLAREAILKAKDSPILIVDQFFPWKGHLFDIEKELGIENQFKYAIYSDGKAWRVQAVSIDPTSFTCRLPLPEPWRGIRDEKLSELTGIPGCIFVHASGFIGGNQTFEGALEMARKALDFPQN
What are the official names of this protein?
MYG1 protein C694.04c.
What is the protein family that this protein belongs to?
Belongs to the MYG1 family.
Protein: 14KL_BRUME
Sequence: MNSFRKTCAGALALIFGATSIVPTVAAPMNMDRPAINQNVIQARAHYRPQNYNRGHRPGYWHGHRGYRHYRHGYRRHNDGWWYPLAAFGAGAIIGGAISQPRPVYRAPAGSPHVQWCYSRYKSYRASDNTFQPYNGPRKQCRSPYSR
What is the function of this protein?
Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose.  Essential for virulence.  May be involved in LPS biosynthesis or polysaccharide transport (By similarity).
What are the official names of this protein?
Lectin-like protein BA14k.
What is the protein family that this protein belongs to?
Belongs to the BA14k family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PSA_SULIL
Sequence: MAFGPAAMGYDRAITIFSPDGSLYQVDYAFEAVKKGWTAIGIKSKSGVVIASEKRKAQSLLDVDSIEKVFLIDDHVGCSFAGLASDGRVLIDYARNIALQHRLIYDEPVSIDYLTKSVADVKQMYTQHGGVRPFGVALVIAGIDKSVPKLYMTEPSGQYMPYQAVAIGQGYYTATEFLEKNYKEDLTIEDTILLALKALSATLKPNEKLTPNTVEIGYASTQTGLFLKMTSEDKNMYLQKL
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PsmA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_STAA8
Sequence: MLDNKDIATPSRTRALLDKYGFNFKKSLGQNFLIDVNIINNIIDASDIDAQTGVIEIGPGMGSLTEQLARHAKRVLAFEIDQRLIPVLNDTLSPYDNVTVINEDILKANIKEAVENHLQDCEKIMVVANLPYYITTPILLNLMQQDIPIDGYVVMMQKEVGERLNAEVGSKAYGSLSIVVQYYTETSKVLTVPKSVFMPPPNVDSIVVKLMQRTEPLVTVDNEEAFFKLAKAAFAQRRKTINNNYQNYFKDGKQHKEVILQWLEQAGIDPRRRGETLSIQDFAKLYEEKKKFPQLEN
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HM12_CAEEL
Sequence: MMFSSIDSLLKISTSSQNEDQKLESHPSPPSQIPNYSTSCSEELMKMAAKAAQFAAQASLENSFSSSTSPTSTVTPLSAYTSLVQPVLPLIYDHLALTYSVNAWQAWGKMRRPRTAFSSEQLVQLEKQFSDNRYLSRPRRYQLAQQLSLSETQIKIWFQNRRMKNKRCPSSTPIQSTSSS
What is the function of this protein?
Transcription factor (PubMed:17289921).  Plays a role, downstream from homeobox protein unc-4 and Wnt signaling, in specifying synaptic inputs to A-class motor neurons (PubMed:17289921, PubMed:22619391).  Involved in patterning of the synaptic outputs of the postmitotic DA class cholinergic motor neurons (PubMed:34388088).
What are the official names of this protein?
Homeobox protein ceh-12.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS17_BRASB
Sequence: MPKRTLQGVVVSDKQAKTVVVRVDRRFTHPIYKKTIRRSKNYHAHDESNEFKPGDMVWIEESKPISKLKRWTVVRGEHKKTA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: NCAP_I75A0
Sequence: MASQGTKRSYEQMETDGERQNATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAFDERRNRYLEEHPSAGKDPKKTGGPIYKRVDGKWMRELVLYDKEEIRRIWRQANNGDDATAGLTHMMIWHSNLNDTTYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRKTRSAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFSARSALILRGSVAHKSCLPACVYGPAVASGYNFEKEGYSLVGIDPFKLLQNSQVYSLIRPNENPAHKSQLVWMACHSAAFEDLRLLSFIRGTKVSPRGKLSTRGVQIASNENMDTMESSTLELRSRYWAIRTRSGGNTNQQRASAGQISVQPAFSVQRNLPFDKSTIMAAFTGNTEGRTSDMRAEIIRMMEGAKPEEVSFRGRGVFELSDEKATNPVVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: DUT_PARL1
Sequence: MNPLIDVRVQRLPHSDGLPLPRYETSGAAGMDLIAALPEGEPMVLAPGERAMVPTGLAIALPQGFEAQVRPRSGLAAKNGVTVLNSPGTVDCDYRGEVKVILINHGADAFTIERGTRIAQMVVSPVTQARFEEVETLDETARGAGGFGSTGTKGR
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: FOLX_SHIFL
Sequence: MAQPAAIIRIKNLRLRTFIGIKEEEINNRQDIVINVTIHYPADKARTSEDINDALNYRTVTKNIIQHVENNRFSLLEKLTQDVLDIAREHHWVTYAEVEIDKLHALRYADSVSMTLSWQR
What is the function of this protein?
Catalyzes the epimerization of carbon 2' of the side chain of 7,8-dihydroneopterin triphosphate (H2NTP) to form 7,8-dihydromonapterin triphosphate (H2MTP).  Is required for tetrahydromonapterin biosynthesis.
What are the official names of this protein?
Dihydroneopterin triphosphate 2'-epimerase, D-erythro-7,8-dihydroneopterin triphosphate epimerase.
What is the protein family that this protein belongs to?
Belongs to the DHNA family.
Protein: SM21_SCHMA
Sequence: MDSPMEKFIQTYLTLLRDGDETVETSKLSESCRKEKLDMKQVNEWIALFDVDKDQKITFEEFCRGLGLKQNEMRIERNHIKTVQSGREQSLPEGVSIIASTMPKPKQVEVTQLFKDIYNEVKKDPDMNKVVKTFKSELERRYGRVWQVNAVTHSYWASFSHEPFQSIQFQYDNKIILAWRTPSN
What are the official names of this protein?
Antigen Sm21.7, Tegumental-allergen-like protein-2, SmTAL1, TAL1.
Protein: SYFA_RALPJ
Sequence: MSLDLDQVVVDAQNAFASVEDNASLENEKARFLGKSGVLTDLLKGLGKLDPETRKTEGARINQAKSRVEEALTARRQALADALMNARLAAEAIDVTLPGRDVAEGSLHPVMNTWERVAKIFGSIGFDVADGPEIESDWMNFTALNNPDNHPARSMQDTFYIDGRDSEDKLLLLRTHTSPMQVRYARMHVEKYKHLDRIPPIKVIAPGRTYRVDSDATHSPMFHQVEGLWIADNISFADLKGVYTDFLRNFFERDDIQVRFRPSYFPFTEPSAEIDMAFGNGKWLEISGSGQVHPTVVRNMGLDPERYIGFAFGSGLERLTMLRYGINDLRLFFEGDVRFLRQFA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPX_LACLC
Sequence: MRFNHFSIVDKNFDEQLAELDQLGFRWSVFWDEKKILKDFLIQSPSDMTALQATAELDVIEFLKSSIELDWEIFWNIALQLLDFVPNFDFEIGKAFEYAKNSNLPQIEAEMTTENIISAFYYLLCTRRKTGMILVEHWVSEGLLPLDNHYHFFNDKSLATFDSSLLEREVLWVESPVDSEQRGENDLIKIQIIRPKSTEKLPVVMTASPYHLGINDKANDLALHDMNVELEEKTSHEIHVEQKLPQKLSAKAKELPIVDKAPYRFTHGWTYSLNDYFLTRGFASIYVAGVGTRSSDGFQTSGDYQQIYSMTAVIDWLNGRARAYTSRKKTHEIKASWANGKVAMTGKSYLGTMAYGAATTGVEGLELILAEAGISSWYNYYRENGLVRSPGGFPGEDLDVLAALTYSRNLDGADFLKGNAEYEKRLAEMTAALDRKSGDYNQFWHDRNYLINTDKVKADVLIVHGLQDWNVTPEQAYNFWKALPEGHAKHAFLHRGAHIYMNSWQSIDFSETINAYFVAKLLDRDLNLNLPPVILQENSKDQVWTMMNDFGANTQIKLPLGKTAVSFAQFDNNYDDETFKKYSKDFNVFKKDLFENKANEAVIDLELPSMLTINGPVELELRLKLNDTKGFLSAQILDFGQKKRLEDKVRVKDFKVLDRGRNFMLDDLVELPLVESPYQLVTKGFTNLQNQSLLTVSDLKADEWFTIKFELQPTIYHLEKADKLRVILYSTDFEHTVRDNRKVTYEIDLSQSKLIIPIESVKN
What is the function of this protein?
Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
What are the official names of this protein?
Xaa-Pro dipeptidyl-peptidase, X-Pro dipeptidyl-peptidase, X-prolyl-dipeptidyl aminopeptidase, X-PDAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S15 family.
What are the subcellular locations of this protein?
Cytoplasm.