PharMolix/UniProtQA huggingface dataset:
Protein: RL14_SHEB8
Sequence: MIQMQSTLDVACNSGARRVQCIKVLGGSHRRYAGIGDIIKVSVKEAIPRAKAKKGDVYNAVVVRTKKGVRRPDGSVIRFDRNAAVLLNNNLQPIGTRIFGPVTRELRNEQFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: HSLU_TERTT
Sequence: MSQMTPREIVSELDKFIVGQQAAKKAVAIALRNRWRRMQVDKSLRNEITPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGRDVESIVRDLVDGSIKLFREQEMAKCRYRAMEAAEERILDALLPPARSSGEEQHESSTRQIFRKKLREGDLDDKEIEIEMAATPVGVEIMAPPGMEDMTSQLQNMFSSMSSGKTRKAKLTVKKAFKKLTDEEAAKLINEEELKAQAIEAAEQNGIVFIDEIDKVTKRDNASGADVSREGVQRDLLPLIEGCTVSTKHGMIKTDHILFIASGAFHLSKPSDLIPELQGRLPIRVELEALSPEDFERILTEPDASLTEQHQALLATEGVSLAFSKDGIRRIAETAFDVNERTENIGARRLHTVLEKLLEEASFNTDGESVEIVVDAAFVDKQLGELATNEDLSRYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_SHEWM
Sequence: MAKSPSRSPRKRVRKQVADGMAHIHASFNNTIITITDRQGNALSWATSGGSGFRGSRKSTPFAAQVAAERAGVAAQDYGVKNLEVFVKGPGPGRESAIRALNSVGYKITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: TAAR6_MOUSE
Sequence: MGSNSSPPTVLQLCYENVTGSCVKTPYSPGSRVILYAVFGFGAVLAVFGNLMVMISILHFKQLHSPTNFLIASLACADFGVGISVMPFSMVRSIESCWYFGRSFCTFHTCCDVAFCYSSLFHLSFISIDRYIAVTDPLVYPTKFTVSVSGICIGVSWILPLVYSGAVFYTGVYDDGLEELSSALNCVGGCQVVVNQNWVLIDFLSFLIPTLVMIILYGNIFLVARQQAKKIENIGSKTESSSESYKARVARRERKAAKTLGITVVAFMISWLPYSIDSLVDAFMGFITPAYIYEICVWCAYYNSAMNPLIYALFYPWFKKAIKVIMSGQVFKNSSATMNLFSEQI
What is the function of this protein?
Orphan olfactory receptor specific for trace amines.
What are the official names of this protein?
Trace amine-associated receptor 6, TaR-6, Trace amine receptor 6, mTaar6.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNPH_ANASK
Sequence: MRKNGRGELDLRPILLEPRVSKHAEGSCLVRFGDTHVLCTASVDEKVPPHVYGTGAGWVTAEYGMLPRSTHERMQREAARGKQTGRTLEIQRLVGRALRAAVDLRAIGPRTVTLDCDVIQADGGTRTAAITGAYVALVQAVRGIQKRRQLAQDPVKRSVAAVSVGIVAGQVHLDLDYDEDSTAEVDMNVVATGDGALVEVQGTAEGKPFPRAELDRMLDAALAGLSRLKELQEAALRTP
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: PRMA_SHESW
Sequence: MPWIQLRINTNSDDAETISDLLMEEGSVSITFEDGKDTPIFEPKLGETPLWRDTVVVALFEADTDLTPTIEMLKTLPFLGDNFSHKIEQIEDKDWVREWMDNFHPIQFGSRLWICPSWREIPDPTAVNVILDPGLAFGTGTHPTTALCLEWLDSLDLSNEEVIDFGCGSGILAVAALKLGAKKVTGIDIDYQAIDASRANAERNNVADKLALYLPEDQPADLKADVLVANILAGPLRELAPLIAERVKSGGKLALSGLLKEQAQEISDFYSQWFDMDEAAHKEDWSRLTGKRK
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OXLA_MOUSE
Sequence: MAGLALRLVLAATLLGLAGSLDWKAASSLNPIEKCMEDHDYEQLLKVVTLGLNRTSKPQKVVVVGAGVAGLVAAKMLSDAGHKVTILEADNRIGGRIFTFRDEKTGWIGELGAMRMPSSHRILHKLCRTLGLNLTQFTQYDENTWTEVHNVKLRNYVVEKMPEKLGYNLNNRERGHSPEDIYQMALNKAFKDLKALGCKKAMNKFNKHTLLEYLLEEGNLSRPAVQLLGDVMSEEGFFYLSFAEALRAHACLSDRLRYSRIVGGWDLLPRALLSSLSGALLLNAPVVSITQGRNDVRVHIATSLHSEKTLTADVVLLTASGPALQRITFSPPLTRKRQEALRALHYVAASKVFLSFRRPFWHEEHIEGGHSNTDRPSRLIFYPARGEGSLLLASYTWSDAAAPFAGLSTDQTLRLVLQDVAALHGPVVFRLWDGRGVVKRWAEDPHSQGGFVVQPPLYGREAEDYDWSAPFGRIYFAGEHTALPHGWVETAVKSGLRAAVRINNNYGYGEVDPQMMEHAYAEANYLDQYPEGERPEEQQAREEVSPDEQEPSHKHLLVETSPEGQQHAFVEAIPELQGHVFVETVPQEKGHAHQNIYPSEHVQVHGEVIPEWHGHGGSGTPQMHRVGDHS
What is the function of this protein?
Secreted L-amino-acid oxidase that acts as a key immunoregulator (PubMed:32818467).  Has preference for L-aromatic amino acids: converts phenylalanine (Phe), tyrosine (Tyr) and tryptophan (Trp) to phenylpyruvic acid (PP), hydroxyphenylpyruvic acid (HPP), and indole-3-pyruvic acid (I3P), respectively (PubMed:15383589).  Also has weak L-arginine oxidase activity (By similarity).  Acts as a negative regulator of anti-tumor immunity by mediating Trp degradation via an indole pyruvate pathway that activates the transcription factor AHR (PubMed:21469114, PubMed:28405502, PubMed:32818467).  IL4I1-mediated Trp catabolism generates I3P, giving rise to indole metabolites (indole-3-acetic acid (IAA) and indole-3-aldehyde (I3A)) and kynurenic acid, which act as ligands for AHR, a ligand-activated transcription factor that plays important roles in immunity and cancer (By similarity).  AHR activation by indoles following IL4I1-mediated Trp degradation enhances tumor progression by promoting cancer cell motility and suppressing adaptive immunity (PubMed:32818467).  Also has an immunoregulatory function in some immune cell, probably by mediating Trp degradation and promoting downstream AHR activation: inhibits T-cell activation and proliferation, promotes the differentiation of naive CD4(+) T-cells into FOXP3(+) regulatory T-cells (Treg) and regulates the development and function of B-cells (PubMed:25778793, PubMed:29288206).  Also regulates M2 macrophage polarization by inhibiting T-cell activation (PubMed:26599209).  Also has antibacterial properties by inhibiting growth of Gram negative and Gram positive bacteria through the production of NH4(+) and H2O2 (By similarity).
What are the official names of this protein?
L-amino-acid oxidase, LAAO, LAO, Interleukin-4-induced protein 1, IL4-induced protein 1, mIL4I1, Protein Fig-1, mFIG1.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Secreted at the immunological synapse. SUBCELLULAR LOCATION: [Isoform 1]: Lysosome. SUBCELLULAR LOCATION: [Isoform 2]: Lysosome.
Protein: MTNA_XYLF2
Sequence: MHHPLPPDDTLYDQVRPILWTGHFLKLLDQRKLPFVVEYVECHSSEDVTQAIRTLIVRGAPAIGIVAGWGAVLAAREIEAVDGIEALCKLEPALQRLHAARPTAVNLAWVLARMRRTLSAAHADWRQVMECEAESIAREDLTANRCMGAYGAALIPIGSGVLTHCNTGSLATAGFGTALGVIRDGIAQGRIARVFVGETRPWLQGARLTVWELQQDGIDATLIADSAAAHLMKSGQVQWVIVGADRICANGDTANKIGTYQLAITARHHGVKFMVVASAATVDMDTVAGEAIEIEQRDPEELLGVSGVRTVAEGIAAWNPVFDVTPGALIDAIVTERGVIQSPDAAQMRATFGN
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: RLMG_PSYIN
Sequence: MNEALNIADQTLVLHRHPRIKNETLQAWDSADEYLINYFSENELQKQLNENEQILLVNDSFGALTCYLQAFQRTVVSDSYLSINSIKLNMQRNRCPEENLLLQDSLQQFPENVKIVLIKIPKTLSYLEEMLQKLHAVITPETIVVAAGKVNMIHNSTLDLFEKYIGTTKTSLAKKKSRLIFSLPIIKEVPEKEIAITWEIEKLDWKIHNHANVFSRNHLDIGGRFLMDNLPKGDFSKVVDLGCGNGIIGMAASAAYPKAQITFIDESYMSIDSARINMQKNLPEEQAENARFVVNNGLVGFKPRSYDLILCNPPFHQQQTITDQIAWSMFNDAHFCLVDNGELVIVGNHHLNYQDKLERIFGNCEIVSQNKKFVILRAVKMD
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_RALPJ
Sequence: MHLTDLIEKTLTAMGYELVEVERAPAGLLRVYIDQAENGVVIEDCEKVSHQLTRVFEVENVNYERLEVSSPGLDRPLRTLADFTRFAGLEAKVTLRLPVDGQKNFTGIIQAPTGEPGQERIGLEFEGKEGPALLGFTLSELDRARLVPVLDFKGNRNKGNKQ
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_PROM1
Sequence: MALKEMVGTVVSDKMQKTVVVAVENRFPHPIYQKIISRTTRYKAHDAENHCKVGDRVRIKESPPISAHKRWTVTDVLVKGMKSKEAAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: SRP1_MAIZE
Sequence: MTSESSTPTGSTRALPASITRSSSSTLSTRPSASTPASTGSLTPSTSTASLVVSPPPARSPVVSTRATATTRPRLAAERPGSATTPCPCGDTDKQLAPCLQEGAGFVIRNAAVRLYMRFGRVWFWHCMLGLWGVGNLIW
What is the function of this protein?
Involved in drought, heat, cold, and/or salt tolerance.
What are the official names of this protein?
Stress-related protein 1.
Protein: LEPA_ACICJ
Sequence: MTSTPTELIRNFSIIAHIDHGKSTLADRLIQTTGALSAREMTEQVLDNMDIEKERGITIKAQTVRLNYKAKDGKTYVLNLMDTPGHVDFAYEVSRSLAACEGSLLVVDASQGVEAQTLANVYQAIDANHEIVPVLNKIDLPAAEPERVKQQIEDVIGLDASDAVEISAKTGLNIEAVLEALVTRLPPPKGDETAPLKAMLVDSWYDSYLGVIILVRVRDGRLRKGQRVRMMSTGAVHTIDQVGTFSPKLTPQADLGPGEIGYITAAIKTVADCNVGDTITDDRAPATEPLPGFKPSIPVVWCGLYPVDADDFEKLRDSLAKLRLNDASFHYEAETSAALGFGFRCGFLGLLHLEIIQERLSREFDLDLIATAPSVVYRLYKTSGEMMELHNPADMPDGSVIDHIEEPWIRATIMVPDDYLGAVLTLCNERRGQQVDLTYVGNRAMAVYRLPLNEVVFDFYDRLKSVSRGYASFDYQMDDYVEGDLVKISILVNQEPVDALAFIAHRSVADTRGRAICAKLKDLIPRQLFKIAIQAAIGGRVIARETLGALSKDVTAKCYGGDISRKRKLLEKQKEGKKRMRQFGKVEIPQTAFLAALKMDA
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ENGB_STRR6
Sequence: MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINTMLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYLTTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESAIKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: VCIP1_MOUSE
Sequence: MSQPPPPPPLPPPPPPPEAPQTSSSLAAAASPGGLSKRRDRRILSGSCPDPKCQARLFFPASGSVSIECTECGQRHEQQQLLGVEEVTDPDVVLHNLLRNALLGVTGAPKKNTELVKVMGLSNYHCKLLSPILARYGMDKQTGRAKLLRDMNQGELFDCALLGDRAFLIEPEHVNTVGYGKDRSGSLLYLHDTLEDIKRANKSQECLIPVHVDGDGHCLVHAVSRALVGRELFWHALRENLKQHFQQHLARYQALFHDFIDAAEWEDIINECDPLFVPPEGVPLGLRNIHIFGLANVLHRPIILLDSLSGMRSSGDYSATFLPGLIPAEKCTGRDGHLNKPICIAWSSSGRNHYIPLVGIKGAALPKLPMNLLPKAWGVPQDLIKKYIKLEEDGGCVIGGDRSLQDKYLLRLVAAMEEVFMDKHGIHPSLVADVHQYFYRRTGVIGVQPEEVTAAAKKAVMDNRLHKCLLYGALSELHVPSEWLAPGGKLYNLAKSTHGQLRPDKNYSFPLNNLVCSYDPVKDVLLPDYGLSNLTACNWCHGSSVRRVRGDGSIVYLDGDRTNSRSTGGKCGCGFKHFWEGKEYDNLPEAFPITLEWGGRVVRETVYWFQYESDPSLNSNVYDVAMKLVTKHFPGEFGSEILVQKVVHTILHQTAKKNPDDYTPVNIDGAHAQRVGDVQGQELESQLPTKIILTGQKTKTLHKEELNMSKTERTIQQNITEQASVMQKRKTEKLKQEQKGQPRTVSPSTIRDGPSSAPATPTKAPYSPTTSKEKKIRITTNDGRQSMVTLKPSTTFFELQESIAREFNIPPYLQCIRYGFPPKELMPPQAGMEKEPVPLQHGDRITIEILKGRAEGGPSTAAHSAHTVKQEEIAVTGKLSSKELQEQADKEMYSLCLLATLMGEDVWSYAKGLPHMFQQGGVFYNIMKKTMGMADGKHCTFPHLPGKTFVYNASEDRLELCVDAAGHFPIGPDVEDLVKEAVSQVRAEATTRSRESSPSHGLLKLGSGGVVKKKSEQLHNVTAFQGKGHSLGTASSHPHIDPRARETLAVRKHNTGTDFSNSSIKTEPPVFTAASSNSELIRIAPGVVTMRDGRQIDPDVVEAQRKKLQEMVSSIQASMDKHLRDQSAEQAPSDLSQRKVEVVSSVRPVNLQTGLPEPFSLTGGTENLNTETTDSHVADVLGAAFATRSKAQKENSMEEPEEMDSQDAETTNTTEPMDHS
What is the function of this protein?
Deubiquitinating enzyme involved in DNA repair and reassembly of the Golgi apparatus and the endoplasmic reticulum following mitosis (By similarity).  Necessary for VCP-mediated reassembly of Golgi stacks after mitosis.  Plays a role in VCP-mediated formation of transitional endoplasmic reticulum (tER).  Mediates dissociation of the ternary complex containing STX5A, NSFL1C and VCP (By similarity).  Also involved in DNA repair following phosphorylation by ATM or ATR: acts by catalyzing deubiquitination of SPRTN, thereby promoting SPRTN recruitment to chromatin and subsequent proteolytic cleavage of covalent DNA-protein cross-links (DPCs).  Hydrolyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitin chains (By similarity).
What are the official names of this protein?
Deubiquitinating protein VCPIP1, Valosin-containing protein p97/p47 complex-interacting protein 1, Valosin-containing protein p97/p47 complex-interacting protein p135, VCP/p47 complex-interacting 135-kDa protein.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Endoplasmic reticulum. Golgi apparatus, Golgi stack. Note=Associated with Golgi stacks and endoplasmic reticulum (By similarity). Displays cytoplasmic to nuclear translocation in response to DNA-protein cross-links (DPCs)-inducing agents (By similarity).
Protein: HABP4_RAT
Sequence: MKGALGSPVAAAGAAMQETFGCVVANRFHQLLDDESDPFDILREAEHRRQQQLQRKRRDEAAAASGAGHRGGRSPAVASGHRPGAAGRRESQKERKSLAVSSAQQPDSPGGPQPPGQKRTPRRGEQQGWNDNRGTDVVLDRAERRSYREYRPYDTERQAESTAEKFTDEKPVDRFDRDRPLRGRGGPRGGLRNRGRGGPGNRAFDSFDQRGKRDFERYGSSDKANRMEDSMGGCGVRTWGSGKDTSDTEPPAPMEETSMMEECQGVLDEESASKVPELEVEEENQVQEMTLDEWKNLQEQTRPKPEFNIRKPESTVPSKAVVIHKSRYRDDIVKDDYEDESHVFRKAANDITSQLEINFGNLPRPGRGARGSTRGGRGRIRRTENYGPRAEVVTQDVAPNPDDPEDFPALA
What is the function of this protein?
RNA-binding protein that plays a role in the regulation of transcription, pre-mRNA splicing and mRNA translation (PubMed:15862299).  Negatively regulates DNA-binding activity of the transcription factor MEF2C in myocardial cells in response to mechanical stress (PubMed:15862299).  Plays a role in pre-mRNA splicing regulation.  Binds (via C-terminus) to poly(U) RNA.  Involved in mRNA translation regulation, probably at the initiation step (By similarity).  Seems to play a role in PML-nuclear bodies formation (By similarity).
What are the official names of this protein?
Intracellular hyaluronan-binding protein 4, IHABP-4, IHABP4, Hyaluronan-binding protein 4, Ki-1/57 intracellular antigen.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, Stress granule. Cytoplasm, sarcoplasm. Nucleus, nuclear body. Nucleus, nucleolus. Nucleus speckle. Nucleus, Cajal body. Nucleus, gem. Note=Transported into the nuclear compartment in activated leukocytes. Inhibition of methylation alters its distribution between the nuclear and cytoplasmic compartments. Methylation may be required for its localization in subnuclear structures, such as nucleoli, nuclear speckles, Cajal bodies and Gemini of coiled bodies (gems). Colocalizes with FMR1, FXR1 and FXR2 in cytoplasmic stress granules (By similarity). In myocardial cells, localization at the sarcoplasm is reduced in response to mechanical stress (PubMed:15862299).
Protein: DSB_RICCN
Sequence: MRSIFIILIFLLFLSSCSEEKAQDKNHEEKQIIEHETQNNETSKATNQEAVNSENTTESIVPANDNNQTDEVSTPASQKQKNPAIKAVKVTFKVDDNDMVLGNKKSNVIVVEYFSPTCPHCAYYHQTIFPELKKKYIDTNKIAYVVREFIATKQDLDAAILARCKGDTNSFTQLHNIILIQQDKWAYSNKYRELLTDIGQLGGISPEEYKQCLNNDKITAILIANTNFVAKAPQFIGTPSFFVNGVQTGNYSIDTISTAVDKALEEQKEKAKNEMSL
What is the function of this protein?
May be required for disulfide bond formation in some proteins.
What are the official names of this protein?
Putative protein-disulfide oxidoreductase RC0029.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbA subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: RB87F_DROME
Sequence: MAEQNDSNGNYDDGEEITEPEQLRKLFIGGLDYRTTDDGLKAHFEKWGNIVDVVVMKDPKTKRSRGFGFITYSQSYMIDNAQNARPHKIDGRTVEPKRAVPRQEIDSPNAGATVKKLFVGGLRDDHDEECLREYFKDFGQIVSVNIVSDKDTGKKRGFAFIEFDDYDPVDKIILQKTHSIKNKTLDVKKAIAKQDMDRQGGGGGRGGPRAGGRGGQGDRGQGGGGWGGQNRQNGGGNWGGAGGGGGFGNSGGNFGGGQGGGSGGWNQQGGSGGGPWNNQGGGNGGWNGGGGGGYGGGNSNGSWGGNGGGGGGGGGFGNEYQQSYGGGPQRNSNFGNNRPAPYSQGGGGGGFNKGNQGGGQGFAGNNYNTGGGGQGGNMGGGNRRY
What is the function of this protein?
This protein is a component of ribonucleosomes.  Could be needed to organize a concentration gradient of a dorsalizing morphogen (Dm) originating in the germinal vesicle.
What are the official names of this protein?
Heterogeneous nuclear ribonucleoprotein 87F, HRP36.1 protein, Protein P11.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nuclear and/or cytoplasmic.
Protein: RL2_CAUVN
Sequence: MALKQFNPTSPGQRGLVLIDRSELHKGRPEKKLVEGLTKSGGRGGNGRIAVRFRGGGAKRLYRLVDFKRRKQGVATVVRLEYDPNRTAFIALIKYQADGELAYILAPQRLKAGDEVVTAEKVDVKPGNASPLRTLPIGTIIHNIELKPAKGGQIARSAGAYAQLVGRDAGYAQIRLNSGELRMVLDTCMATVGAVSNPDHMNQNLGKAGRSRHMGRRPHVRGVAMNPVDHPHGGGEGRTSGGRHPVTPAGKPTKGAKTRVNKATDKFIIRSRHKAKKGR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: GDT4_DICDI
Sequence: MKLEQRIFFLICLVINSFSNCSLLVAPDGYYNIYRENKIENILNLKPNGNKSQDSYYPDVCSKAVKNKEGVKSFILSSFPLSTKEYANVIVTKGSHMTLGDGEYHQIFNINRFLNIVCVEGSLVFSTKDVVYMSALVILPGGNFECIDCTIKFRDLYPTNSLIDPFGFLPGIITLGGSLSLLGKQKTVYSAVLIDENILEVQDISSLDIFNGYSLFIFSESFPLGKASTFTFNSNQIKVLEIKIPKTDKSIRVFFYSRFSTFSTSTTASIHITGNSNVHIENFYIDSFGRTTNDQYSDTELIFSQDDPNLITGFINGSNQRFRSSLYIEHSNNVTIKNSVILENRGETRSPLIFFGSNVNISGNIISSKSGSSLIAQYGTENIQSTNNYYSLSLPLLKSLNSTLDSMDYGNEGNGIFSISPKINSINDIFNGQIIAINHIILSDRSSITGFDKDCYSPCYNDSIRVSSKVQHSVEFKITGSTFISSSNYSESSFLFRISETGSKQSSFYKIINSNLSYPISVLLENNAFILDNVYGFGNFTINGLIKRLDIINSTLDPSVTSSISLSNFSKAISIQNSFMDYRSFQKQNNQIYGSIITPYLYYFENTMNLIKVSKMYPNVNHQILAGTVLNMGIEIIIIAPLFGKMDCIFEDESGIQTIPFNKSSNSCVLPYLFKNEGSFNVRVTLSLTKSLDNIIFQVYFPMVTVFNIYSFYSGWAMIDSNIEKEIIIDGNIFKKGCQQQVLGNCTISTNSKLITGLPSVTESDKLNRLFSSGITSINPYEPVTITIPIDKESKKNQIQLFFTHQPIDIETSLLSIYVENQPIFLLEPLQSNLDSTFKNLTFHYENSKSLEKIKITFITRGDIYLTSTAIYSSTNQPIYNEVIGINEQLNILAIVLPITISLFAAASILAGYLVIKKYKKPNMYYNRNTNGNIGMKVFSTKFKRRPKKVIPLSIPLSTNRITKKSLQSLDSMAENPVILLSIPELEKANEPEFNPEKTFLQESELLDLPTPKVEPEEPRINIVPLPRFPTVYKKEDNDKLLKELNITGPITSENIESFFEVDVGLPSLIIKNESEIILQEIDYIETGEIQEMEGSFLEDKSTDTTVIVTKSDGLPKFFQTKVFSKRFNDISKFDNDFFDLKEYIVEHQEESFEIPFMTSEDEVDETKINIIDFLLSPKSNKVALNMYLKSFQNRNHKLCYGKYGSNKNSILVIEGTSYYYDCTDVRLPISTPRSNLNFGITDGNKCIVDRKYRERLQYINVYSEPFRIYTLFPDSNDNVTITTSECCKEIDPFGSLDVDIFVTLKTTTKFNEKVTIRYETDDKELAFSTFVYLNLESQVSSKIDFDEIVLEKYLSEGSFGVVYSAIWRSSSVAVKLFKHHYSKDEIDKETSILSKIKHPNIVSFIGSLNFLNTYGIVIDYHPRGSLNYYTRNQNIKLSMVQNIRISLDISRACSFLHKNGIIHRDLKPDNVLIVSFDPDSSICAKISDFGTCREINGKHELNSKAGTTRYMSPEILEGLPYTYSTDVYSFAILFFELLSGRVPFREIPKREIPRFVRLGTRPRLDQDVFADNDISLILLACWNPNPRGRPTFDTLIDLLEKLLKKYKERAKRNKKNQNQ
What are the official names of this protein?
Probable serine/threonine-protein kinase gdt4, Growth-differentiation transition protein 4.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: TOG3C_AGEAP
Sequence: NCIDFGGDCDGEKDDCQCCXRNGYCSCYNLFGYLKRGCKXEVG
What is the function of this protein?
Omega-agatoxins are antagonists of voltage-gated calcium channels (Cav).
What are the official names of this protein?
Omega-agatoxin-Aa3c, Omega-AGTX-Aa3c, Omega-agatoxin IIIC, Omega-Aga-IIIC, Omega-agatoxin-3C.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 04 (omega-agtx) family. 03 (type II/III omega-agtx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TXCL1_CALPA
Sequence: MKTQVLALFVLCVLFCLAESRTTLNKRNDIEKRIECKCEGDAPDLSHMTGTVYFSCKGGDGSWSKCNTYTAVADCCHQA
What is the function of this protein?
In neuromuscular preparation of crustaceans, the toxin increased neurotransmitter release, causing repetitive firing of the axons.  May affect sodium channels (Nav).
What are the official names of this protein?
Delta-hormotoxin-Cpt1b, Delta-HRTX-Cpt1b, Calitoxin, CLX, Calitoxin-1, CLX-1, Neurotoxic peptide.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: HHIP_MOUSE
Sequence: MLKMLSFKLLLLAVALGFFEGDAKFGERNEGSGARRRRCLNGNPPKRLKRRDRRVMSQLELLSGGEILCGGFYPRVSCCLQSDSPGLGRLENKIFSATNNSECSRLLEEIQCAPCSPHSQSLFYTPERDVLDGDLALPLLCKDYCKEFFYTCRGHIPGLLQTTADEFCFYYARKDAGLCFPDFPRKQVRGPASNYLGQMEDYEKVGGISRKHKHNCLCVQEVMSGLRQPVSAVHSGDGSHRLFILEKEGYVKILTPEGELFKEPYLDIHKLVQSGIKGGDERGLLSLAFHPNYKKNGKLYVSYTTNQERWAIGPHDHILRVVEYTVSRKNPHQVDVRTARVFLEVAELHRKHLGGQLLFGPDGFLYIILGDGMITLDDMEEMDGLSDFTGSVLRLDVDTDMCNVPYSIPRSNPHFNSTNQPPEVFAHGLHDPGRCAVDRHPTDININLTILCSDSNGKNRSSARILQIIKGRDYESEPSLLEFKPFSNGPLVGGFVYRGCQSERLYGSYVFGDRNGNFLTLQQSPVTKQWQEKPLCLGASSSCRGYFSGHILGFGEDELGEVYILSSSKSMTQTHNGKLYKIVDPKRPLMPEECRVTVQPAQPLTSDCSRLCRNGYYTPTGKCCCSPGWEGDFCRIAKCEPACRHGGVCVRPNKCLCKKGYLGPQCEQVDRNVRRVTRAGILDQIIDMTSYLLDLTSYIV
What is the function of this protein?
Modulates hedgehog signaling in several cell types, including brain and lung through direct interaction with members of the hedgehog family.  Soluble forms inhibit Shh-induced differentiation in the fibroblast cell line C3H/10T1/2.
What are the official names of this protein?
Hedgehog-interacting protein, HHIP, HIP.
What is the protein family that this protein belongs to?
Belongs to the HHIP family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Secreted. Note=The last 22 C-terminal amino acids may participate in cell membrane attachment.