PharMolix/UniProtQA huggingface dataset:
Protein: RE114_SACPS
Sequence: MYEYCSVIIKKYSRYTIPSLAPKGFSSVLEPPHIDKWQHLSVNCTLQFKVLLEDSGQVALQVILNNSTFLEHIRLPLGSNHDSIQFSCKCPIISCKYISEEFGPKVLKRFQINLSNEMDFNRIVISLKNLSFIVKTAKTSIARNTMINQTSDFSNSKKGNFNENNNAGTYRNSSVQFQTQNMVMDFSQIYQEKCARELNNCSNITFPMTNLPMTQQNFPTPEANVEHFSQDLNTPSATQTIPIAPEPLSVKLLEASPPLSNKSRHSPTTKKENRNTAISFDLLSKKGAILHNGNDTLNVADLPKKRQSTEDLVQIRSSANVVTTLGTSCNLVKKNATKQNKEKVDNKLSDSQNVAHTNEYQKKKEIPLCGPINGLETKMTLIQEEMMAAKKTSRDPPRKISKRLIKEKLKDEEFMKWVNKVERVLSKMFEK
What is the function of this protein?
Required for meiotic recombination events; not required for mitosis.
What are the official names of this protein?
Meiotic recombination protein REC114.
What is the protein family that this protein belongs to?
Belongs to the REC114 family.
Protein: RS7_ECO7I
Sequence: MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVYSALETLAQRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWIVEAARKRGDKSMALRLANELSDAAENKGTAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: TYSY_RUTMC
Sequence: MKQYLDFLRLVKNTGTNKTDRTGIGTTSLFGYQMRFDLSDGFPLITTKRVHLPSVVHELLWFLSGATNIKYLQENGVRIWNEWADKNGDLGPIYGVQWRNWQNVRGESIDQIMQVIEQIKNTPDSRRIIVSAWNVGELENMALPPCHAFFQFYVALGKLSCQLYQRSADVFLGVPFNIASYALLTHMMAQQCDLEVGDFIWSGGDCHIYSNHTKQVEIQLARTPKTLATLKINNKPDSIFDYNFEDFEFINYVFDAYIKATVAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_MYCFO
Sequence: MSMGILDELDWRGLIAQSTDRETLANDLANGPMTVYSGFDPTAPSLHAGHLVPLLTLRRFQRAGHRPIVLAGGATGMIGDPRDTGERTLNTADTVADWAGRIRGQLERFVEFDDTPTGAIVENNLNWTGRLSAIEFLRDLGKYFSVNVMLDRETVRRRLEGDGISYTEFSYMLLQANDFVELHQRYGCALQIGGSDQWGNIVAGARLVRQKLGATVHAMTTPLVTDSEGKKFGKSTGGGNLWLDPEMTSPYAWYQYFVNTADADVIGYLRWFTFLSADEIAELEDATQNRAHERAAQKRLARELTTLVHGEGATTAVELASQALFGRAELADLDESTLGAALREASNGQVAELKPGGPDSIVDLLVETGLAASKGAARRNVAEGGVYVNNIRIESDEWIPQHSDFLHERWLVLRRGKRHIAGVERVGA
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA4_XENLA
Sequence: MYQSIAMATNHGPSGYEGTGSFMHSATAATSPVYVPTTRVSSMIHSLPYLQTSGSSQQGSPVSGHNMWAQAGVESSAYNPGTSHPPVSPRFTFSSSPPITAPSSREVSYSSPLGISANGREQYSRGLGATYASPYPAYMSPDMGAAWTASPFDSSMLHNLQNRAVTSRHPNIEFFDDFSEGRECVNCGAMSTPLWRRDGTGHYLCNACGLYHKMNGINRPLIKPQRRLSASRRVGLSCANCHTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMKKEGIQTRKRKPKNLSKSKTLTGQSGSDSLTPSTSSTNSMGEEMRPIKIEPGLSPPYDHSNSISQASALSTITSHGSSYYPMPSLKLSPQNHHSTFNPSPQANSKHDSWNNLVLA
What is the function of this protein?
Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3'.  Associated with cardiac specification and can regulate cardiac-specific transcription during embryogenesis.  Activates the expression of cardiac MHC-alpha in vivo.
What are the official names of this protein?
Transcription factor GATA-4, GATA-binding factor 4, xGATA-4.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRUB_CLONN
Sequence: MNGILNVYKPIGITSFDVVCQIKKITGIKKIGHTGTLDPLACGVLPVCIGKGTKVVDYLMKDFKVYDATFKLGIITDTYDREGKELSISEVNVSLDEIECAVNSFLGDSFQVPPMYSALKVNGKRLYELAREGKSIEREARPITIYDINILHIDIPYVKFRVKCSKGTYIRSLCYDIGSNLKCGATMWDLERVQSGAFTKENSIELNKLTTDNINDYIISIDESLNQYDKAFVSSKCEKLLVNGVRIGDKRLLPNLDINKMYRIYSEDNKFLGLGMRNSKGLKIEKLLL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: NUOK_KLEP3
Sequence: MIPLTHGLILAAILFVLGLTGLVIRRNLLFMLISLEIMINAAALAFVVAGSYWGQADGQIMYILAISLAAAEASIGLALLLQLHRRRQNLNIDSVSELRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL7_VESOH
Sequence: MAKLTNEDILNAIADMSVIDVVELVSAMEEKFGVSATAVTPVAVVADVDNTVVEKDEFDIMLTSFGEKKVAVIKAVRSITGLGLKESKDMVESAPVVIKESASKIEAEDIERQLKEVGASVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: PGK_BACTN
Sequence: MQTIDKFNFAGKKAFVRVDFNVPLDENFNITDDTRMRAALPTLKKILADGGSIIIGSHLGRPKGVADKFSLKHIIKHLSELLGVEVQFANDCMGEEAAVKAAALQPGEVLLLENLRFYAEEEGKPRGLAEDATDEEKAAAKKAVKESQKEFTKKLASYADCYVNDAFGTAHRAHASTALIAKYFDTDNKMFGYLMEKEVKAVDKVLNDIQRPFTAIMGGSKVSSKIEIIENLLNKVDNLIIAGGMTYTFTKAMGGKIGISICEDDKLDLALDLIKKAKEKGVNLVLAVDAKIADAFSNDANTQFCAVDEIPDGWEGLDIGPKTEEIFANVIKESKTILWNGPTGVFEFENFTHGSRTVGEAIVEATKNGAFSLVGGGDSVACVNKFGLASGVSYVSTGGGALLEAIEGKVLPGIAAINE
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA2_BACVZ
Sequence: MRSYEKSKAAFKEAQKLMPGGVNSPVRAFKSVDMDPIFMQRGKGSKIFDIDGNEYIDYVLSWGPLILGHTNDRVVESLKKVAENGTSFGASTEVENELAKLVIDRVPSVEIVRMVSSGTEATMSALRLARGYTGRNKILKFEGCYHGHGDSLLIKAGSGVATLGLPDSPGVPEGIAMNTITVPYNDLESVALAFREYGEDIAGVIVEPVAGNMGVVPPQEGFLQGLRDMTEQYGALLIFDEVMTGFRVDYNCAQGYFGVTPDLTCLGKVIGGGLPVGAYGGKADIMERIAPSGPIYQAGTLSGNPLAMTAGLETLQQLTPESYQEFVKKGDMLEEGISKAAAAHGIPHTFNRAGSMIGFFFTNEPVINYEAAKSSDLKLFAKYYKGMADAGVFLPPSQFEGLFLSTAHTMEDIENTIQAAEKVFQAISR
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 2, GSA 2, Glutamate-1-semialdehyde aminotransferase 2, GSA-AT 2.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WALR_STAEQ
Sequence: MARKVVVVDDEKPIADILEFNLKKEGYDVYCAYDGNDAVDLIYEEEPDIVLLDIMLPGRDGMEVCREVRKKYEMPIIMLTAKDSEIDKVLGLELGADDYVTKPFSTRELIARVKANLRRHYSQPAQEVSGATNEITIKDIVIYPDAYSIKKRGEDIELTHREFELFHYLSKHMGQVMTREHLLQTVWGYDYFGDVRTVDVTIRRLREKIEDDPSHPEYIVTRRGVGYFLQQHD
What is the function of this protein?
Member of the two-component regulatory system WalK/WalR.
What are the official names of this protein?
Transcriptional regulatory protein WalR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSCR_TRIT1
Sequence: MEKRGPKRRQQAAHLSCELCRERKVKCDKLDPCTNCSSAGVICVPVRRPRLPRGAHAQRLRRNSPEDPEAPIQIDIASPADAGTIADDDLKKRIRRLEALVDSMRSSSHISKQDQEAEDTIESTLNRIDDDSLLIKTPRVHPSDGGLRILGLSGSSSPETGWASILEDREISMQLCQVYLLNVDPVIKILHRPSVEKWMLQGQRYLGFPERHSAVESLGAAICYVAATSLTETQSWARFHATKSSIVARARRACETTLEKSSPLLSPVITTLQAFLLYLHESFIEQNVLIPLKTHQVARRSEDPSRAVWTLMAFAVRIAKALDLPRGAGDNFFGQQMRKRLWLAICLLDFQTSLSQPSEPLITVAEATSSFSPPKHINDSDFDPTTSHDVPDREGLTDTTFSLVSYHVQAAGRLLNFEPSVKDDGSRQQNVQHFEQRTLRLLLYCDPESTPYAWFTWHRIQCFVSGARLSAIRPLMHQHGDHPISILDTNEGTSILSLALNILEKVQLVHTDPRGEAFRWFVTVPWQPLAIAMSECYICQDIALVQRAWPIVEAAFQQHEATVSGSSKAISITLERLMCRVREKLSPSLGTSTSLTASPIFCATNTANTLSVPHTPPSRSSITSSGDLLGNWSWTTATELLRPGEDLALVTEAPISTSPQKIDPLLFSLDSQLLIAGQEQLVEADQSWAAWDEVIASLHDDETGRANMFLS
What is the function of this protein?
Transcription factor that specifically regulates the neosartoricin B biosynthesis gene cluster (PubMed:23758576, PubMed:23368997).
What are the official names of this protein?
C6 finger domain transcription factor nscR, Neosartiricin B biosynthesis protein R.
What are the subcellular locations of this protein?
Nucleus.
Protein: GATB_PELUB
Sequence: MTKDNSEYLIERRDNVYEVVIGLEVHAQVTSNSKLFSSSSTTFGAEPNTQVSLVDAAFPGMLPVINEYCVKQAIKTGIGLRAQINKRSVFDRKNYFYADLPQGYQISQFKYPIVGEGTVILDMAHGQKEVGIERLHLEQDAGKSIHDMDPQNTLVDLNRSGVALMEIVSKPDMRTPDEVSAYIKKLRSIMRYLGTCDGNMQEGSLRADVNISVRIKGSDKLGTRCEIKNVNSIKFMQMAIDYEANRQVDLIEDGKTIDQETRLFDTKKNETRSMRSKEDAHDYRYFPDPDLLPLEVTDEFIEKLKADIPELPDDKKKRFIDEFKVSAYEATILVSDIETAKYFEEVVAKMGKNKDMKLAVNWITGELFAVLNNKNLEISESPVSAKNLAKLINLIKNGTISGKIAKTIFELMIDGDIDPQIIVEEKGLKQESDPKALEALIDKIIDTNREKAIEYKNGKEKLFGFFVGQAMKVSGGKANPQLINEILKKKLQ
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: PTH_BUCCC
Sequence: MNKIKMIVGLGNSVYKYNQTRHNVGFWYINMLSSFYKTSLKFKKKFSGYVSSFFLNNNKIFLLKPDLFMNLNGYSVFALSSFYKIKLSEILVVRDELDLSPGILKVKYGIGHNGHNGVKSIINTFEKKKPFIQLCIGIGRPEFKKNVSNFVLECPSKIDTINIKKAILKFIFLTKDYIYKKEFLKNKKIILI
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLDD_HYDCU
Sequence: MIVVTGGAGFIGSNIVKALNAQGRTDILVVDNLKNGKKFINIADCDIADYLDKEDFQSRIFAEEGLPDIDCVFHEGACSATTEWDGKYMMDNNYEYSKDLLNYCLNRKIPFLYASSAAVYGDGPTFIEERQYEKPLNVYGYSKFQFDQYVRRILPLAESQVAGFRYFNVYGPREQHKGDMASVAFKLHNQVLAGEKLKLFGAYDGYEAGMQTRDFVFIEDVVNVNLWFMENPEQSGIFNLGPAAAEPFKHIADAVIDFHGQGEIEYIPFPDRLKGAYQSFTQADNTRLRDAGYDKPFHTVSEGVQKYLRWLSDNPRVLDFTKK
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: HTPG_FRATT
Sequence: MSEKKYTFETEVDKLLHLVIHSLYSNREIFLRELVSNSSDAIEKLRYESISNAALNEDDTDYAIRIDFDKDAKTITVSDNGIGMTEEEVIENLGTIAKSGTKKFLESLTGDKSKDNELIGQFGVGFYSSFIVADKVTVRTRKAGQDKSQATKWVSDAQNGFTVETITKEKRGTEVILHIKKEHLDLLEYHVLKGLVNKYSDCINTSIQMKKVEYDKDGKQTVKDEYETVNNTKAIWLRSKDEVTDEEYQEFYKYISHDFADALMWIHNKVEGNLEYNSLLYIPQNKPFDFWNRDKDYGLSLYVRRVFIMENKELLPPYLRFVKGVIDSADLPLNVSREILQHNKVIDKIKKAITTKILSELKKLASKDKEKYQKFWDSFGQVLKEGVSDDYSNKEKIAGLLRFATTQSGDSKQTVSLADYISRMKEGQDTIYYITSDSYKAAANNPQLEAFKKKGIEVILMTDRIDEWMMSTLTEFDGKHMKSIIKGDIDLDRFETPENKEKFEKEAKDFEKVLKEIKEVLKDKVEDVRLSKRLTDSPSCVVVNDYGMSLHMQKMMEEAGQSFMPGMGMKPILELNAEHNLVQKLKNEADTEIFADLSELLLLQAMFVEGAKIEDPMAFVKLVNKYIR
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF5A_PYRIL
Sequence: MSTKYVEVGELKEGSYVVIDGEPCRVVEIEKSKTGKHGSAKARIVAIGVFDGGKRTLSLPVDAQIEVPIIEKFTAQVLSISGNVIQLMDMRDYKTIEVPIDYVEEEAKGRLAPGVEVEVWQILNRYKITRVK
What is the function of this protein?
Functions by promoting the formation of the first peptide bond.
What are the official names of this protein?
Translation initiation factor 5A, Hypusine-containing protein, eIF-5A.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMC4_CANAW
Sequence: MSEVNETCKPQACAIQNCLEKNGYNESRCTKCIDDLYKCCKEFYERQGPDASSVCCPKFKLLQLKLKQRSLGEIDAKVLETRRG
What are the official names of this protein?
Cx9C motif-containing protein 4, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the CMC4 family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Imported into the mitochondria via the mitochondrial disulfide relay system.
Protein: AQPZ_BRUSU
Sequence: MLNKLSAEFFGTFWLVFGGCGSAILAAAFPELGIGFLGVALAFGLTVLTMAYAVGGISGGHFNPAVSLSLTVAGRLPAKDLIPYWVAQVLGAIATAAILYVIASGKDGFSAGGLASNGYGELSPGGYSMMAGLLIEIILTAFFIIIILGSTSSLAPAGFAPIAIGFGLTLIHLVSIPVTNTSVNPARSTGVALFADTAALSQLWLFWVAPLVGAVIGAIIWKGLLGRD
What is the function of this protein?
Channel that permits osmotically driven movement of water in both directions.  It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells.  It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
What are the official names of this protein?
Aquaporin Z.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PHNW_BURP6
Sequence: MPERDPILLTPGPLTTSRMTRDAMLRDWGSWDAAFNRLTKSVCADLVRIAGGGDAYVCVPLQGSGTFAVEATLGTLVPRDARVLVPNNGAYCARIAAILRRLGVAHVELPFAEDEPASAHAIDAALARDARLTHVALVHLETSAGLLNPLDDIAAVCRARGKALIVDAMSSFGALPIALAASGIDALISASGKCLEGVPGMGFAIVRRSALEAAEGRSPSVALDLHDQYAYMQRTSQWRFTPPTHVLAALRAALDQFFDEGGQPARGARYARNCATLVDGMRALGFEPFLDARAQASVIVTFYAPADPAYAFPAFYAAVRDAGYVLYPGKLTTADTFRVGCIGALGADEMRGAVAAIGGALESLGIAMR
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
2-aminoethylphosphonate--pyruvate transaminase, 2-aminoethylphosphonate aminotransferase, AEP transaminase, AEPT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
Protein: RL10_RICBR
Sequence: MLRSEKPEVVEEIASIYKDSPSVIVAHYHGLTVSEVNSLRESLKSKDAGFKVVKNTLAKIAANKAGLDDIVSLFSGPTAIVYSKEPVEMAKLVVNFAKSNENLKIVGGIVDKQVLNEHSIKELSKLPSLNELRSKIVGLLQAPATKIAGVLQAPSSSLARVIQANASKN
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: PTYBC_SHIDS
Sequence: MAKEISSELLNTILTRVGGPGNIASCGNCMTRLRLGVHDSSLVDPNIKTLEGVKGVILTSDQVQVVFGPGKAHRATKAMSELLGEAPVQDAAEIAAQNKRQLKAKQTSGVQQFLAKFATIFTPLIPGFIAAGLLLGIATLIATVMHVPADAQGTLPDALNFMKVFSKGLFTFLVILVGYNAAQAFGGTGVNGAIIAALFLLGYNPAATTGYYAGFHDFFGLPIDPRGNIIGVLIAAWACARIEGMVRRFMPDDLDMLLTSLITLLITATLAYLIIMPLGGWLFEGMSWLFMHLNSNPLGCAVLAGLFLIAVVFGVHQGFIPVYLALMDSQGFNSLFPILSMAGAGQVGAALALYWRAQPHSGLRSQVRGAIIPGLLGVGEPLIYGVTLPRMKPFITACLGGAAGGLFIGLIAWWGLPMGLNSAFGPSGLVALPLMTSAQGILPAMAIYAGGILVAWVCGFIFTTLFGCRNVNLD
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in N-acetylmuramic acid (MurNAc) transport, yielding cytoplasmic MurNAc-6-P.  Is also able to take up anhydro-N-acetylmuramic acid (anhMurNAc), but cannot phosphorylate the carbon 6, probably because of the 1,6-anhydro ring.
What are the official names of this protein?
PTS system N-acetylmuramic acid-specific EIIBC component, EIIBC-MurNAc.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUON_HALHL
Sequence: MSFETPDFSLALPEIWLLAATCGVLVVDLFSSDPRRSATFYLTQGALLVTAVLALSTQWGVNEVTFSGHYMADSLGAVVKASVALLSVLALAYTRPYLGDRGLLQGEFYLLALFANLGMLVIASGGSLLSLYLGLELLSLALYALVAYHRDSRQAAEAAMKYFVLGSLASGILLYGMSMVYGATASLELSVIAEVAGRHSDPLMLLFGVVFMLVGVAFKLGAAPFHAWVPDVYQGAPTPVTLFLSTAPKVAAVALFMRLLVDGLGPMHEQLEPMLMILAVASLLVGNLIAIVQTNFKRMLAYSAIAHAGFIMVGFTAGTDAGHAAALFYTIAYSIMAAGAFGMITVLARSGFEAEEIADLRGLNERHPVYAGVLLLVLVSMTGIPGTVGFYAKYLVLQAAVEAGHIPLAIFAVVAAVVGAFYYLRVLKVVYFDRPEAEVDADTLPAPGASSAIRSLVVVNGVAVLVLGIFPERLIALCQAALGL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRC_LYSSC
Sequence: MKKVLRNVQMLNEQGELQTVNIAMADGKITAIGQEVTVVNAEVIEGNGLIVAPGFVDVHTHLREPGFEHKETIATGSASAAKGGFTTICAMPNTKPVPDSVENMQLINGLIKESAVIRVLPYGSLTKDISGEVRTNVEELKAYGAVAFSDDGVGIQLASTMYEQMKDAAKHDMVVVAHCEDNSLIYDGVMHEGKRNKELDLPGIPSICESVQIARDVLLAEAAGARYHVCHVSTKESVRAVRDAKAAGIRVTAEVCPHHLLLEEMDIPSDDANWKMNPPLRGADDKDSLHAALLDGTIDCIATDHAPHTVEEKCCGMVGAPFGIVGFETAFPLLYTQFVETGKWTLKQLIDWMSVKAAEIFDLPYGTLAVGASADMILIDIQKEQTIDAEGFVSKGRNTPFNGWVAKGWPVLTIFEGNIVYQEAE
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: SASA_CROS5
Sequence: MLEPPNHQTTAKTDQAASMSIQLLLFVDERPSSHEYIQPIRDYIKTVSQDCPCQLEVIEIHEQPHLVEHFRLVATPALVKVVPEPRQTLAGSNLVNQLKKWWPKWLSSLEENHHDSLLEKSSNVGYSGELMRLSDEIFRLKKDKENLQEQLKFKDQVLAMLAHDLRSPLTAASIAVETLELAKNQDPTEKQQKLTAQLFNQTRNQFRVMNRLITDILQASKSMNAQLQVHQTEVFLPRLSKEIVEQYNDLLTEKSLKLIQDVPQDVPGVYADEELIRQVIVNLIDNAIKYTSEGGEITLSILHRTSQKVQVSVCDTGPGIPEEKQERIFEGHFRLQRDQGKEGYGLGLSLCRKIIRVHYGQIWVDSVPGQGSCFHFTLPVYR
What is the function of this protein?
Member of the two-component regulatory system SasA/RpaA involved in genome-wide circadian gene expression.  One of several clock output pathways.  Participates in the Kai clock protein complex, the main circadian regulator in cyanobacteria, via its interaction with KaiC.  KaiC enhances the autophosphorylation activity of SasA, which then transfers its phosphate group to RpaA to activate it.  In addition to its output function, recruits fold-shifted KaiB (KaiB(fs)) to KaiC to cooperatively form the KaiB(6):KaiC(6) complex (independent of SasA kinase activity).  Required for robustness of the circadian rhythm of gene expression and is involved in clock output, also required for adaptation to light/dark cycles.
What are the official names of this protein?
Adaptive-response sensory kinase SasA, Sensor histidine kinase SasA.
Protein: PLSX_PROMM
Sequence: MPPKDSDSSTASGPRSKTTRPRAIRRLVIWYRRNAAVTSLVGSATNSASAAGNVAGTVVSSAGSVVSNAGSMAGSMLQPLVFDPLRRLQSSENNPEAEDIKNSDRLWVAVDGMGGDEAPGPILDGCLKAIQRLPLRIKFVGETEKVLGAVQAMGLTELFNQATAAGHLELVASGPSVGMDEEATVVRRKRDASINLTMDLVKKGEALAMYSAGNSGAMMASAIFRLGRLAGIDRPAIGALFPTKDPTQPVLVLDVGANMDCKPIYLHQFALLGNIYSRDVLQVARPRIGLLNIGEEECKGNDLAIRTHELLSEEHRLQFAGNCEGRDVLSGAFDVVVCDGFTGNVLLKFLESVGSVLLDVLRAELPRGRRGKVGSAFLRSNLKRIKKRLDHAEHGGALLLGVNGICVIGHGSSKALSVVSALRLAHSAASHGVMDDLAELQKAPVESA
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity).
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: LPXK_SHEB9
Sequence: MQALVNKIWYQGHPLRWLLLPLSWLFAVITYVRRALFRLGIKSQTAMPVPVIVVGNITVGGSGKTPTVIYLIELLRQHGFTPGVISRGYGVDIQGVRTVNLGASAVEVGDEPAMIVARTQVPMVVGAKRVDAANALIAEFGVDVIICDDGLQHYALGRDIELVVIDGQRGLGNGLLLPAGPLREGAWRLDAVDFIVNNGGPAAKGQFEMQLAPTEVKPVKCDLTSGEYSFDKSQPLVAMAGIGNPARFFESLRAQGYQLALCQGFDDHQPYDKTQLRDLAQDLPLLMTEKDAVKCRDFAQENWWYLAVNAKLSPQFDEQLLARLREVAAAKQGNFHGIR
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: RS14Z_NANEQ
Sequence: MLKQSGHKHGKLLKILKHNKPKERKFGKGARRCERCGRYDGIIRRYGLYLCKDCFKEVAHELGFFKWGE
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.