PharMolix/UniProtQA huggingface dataset:
Protein: Y2370_VIBA3
Sequence: MKVYDCCDLVRELYSQIGSGDQGYIPKAITCAVKTLNDLAADESLPKEARDRAAFAAANLLISDFED
What are the official names of this protein?
UPF0253 protein VS_2370.
What is the protein family that this protein belongs to?
Belongs to the UPF0253 family.
Protein: HIP13_ARATH
Sequence: MPPMKAVLQLSIHEERIRKKAFVTVSRCPGVTSITMDDKTGKMTVVGEVDVPVIVMKLRKLCNTELVSVEVVKPPEKKPEPEKPAPPKPAPAPAKPAEIVAWPVQMNNPYQYNPAYANSYYQPYGNSRFVTDESNCVIM
What is the function of this protein?
Probable heavy-metal-binding protein.
What are the official names of this protein?
Heavy metal-associated isoprenylated plant protein 13, AtHIP13.
What is the protein family that this protein belongs to?
Belongs to the HIPP family.
Protein: GLGC_MYCSS
Sequence: MRELPHVLGIVLAGGEGKRLYPLTADRAKPAVPFGGAYRLIDFVLSNLVNARYLRICVLTQYKSHSLDRHISQNWRLSGLAGEYITPVPAQQRLGPRWYTGSADAIYQSMNLIYDEDPDYIVVFGADHVYRMDPEQMVQFHIESGAGATVAGIRVPRAEATAFGVIDADESGRIRSFVEKPADPPGTPDNPDEAFVSMGNYIFTTKVLIDAIRADADDDDSDHDMGGDIIPRLVSDGMAAVYDFSNNEVPGATERDHGYWRDVGTLDAFYDAHMDLVSVHPIFNLYNKRWPIRGESENLAPAKFVNGGSAQESVVGAGSIISAASVRNSVLSSNVYIDDGAIVEGSVIMPGTRIGRGAVVRHAILDKNVVVGPGEMVGVDLEKDRERFSVSAGGVVAVGKGIWI
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block, required in the biosynthesis of maltose-1-phosphate (M1P) and in the elongation reactions to produce linear alpha-1,4-glucans.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: TRIQK_XENLA
Sequence: MGKKDASTTRTPVDQYRKQIGRQDYKKNKPVLKATRLKAEAKKAAIGIKEVILVTIAILVLLFAFYAFFFLNLTKTDIYEDSNN
What is the function of this protein?
Plays a role in cell growth and maintenance of cell morphology.
What are the official names of this protein?
Triple QxxK/R motif-containing protein, Triple repetitive-sequence of QXXK/R protein.
What is the protein family that this protein belongs to?
Belongs to the TRIQK family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: NADK_COXBR
Sequence: MLKIVSKPSFNRIALMGREGVEGVPETLAALKDYLVSLNREVILEENAAHMIDGSRLLTVPANDLKKKADLLIVVGGDGSLLNAAHIAVPQQLSVLGINRGRLGFLTDIPPNELTQISDILDGHYREEVRFLLEGTVEEGDEIVAQGIALNDIVLLPGNAPKMIEFDIFINDEFVCNQRADGLIITTPTGSTAYALSGGGPILHPQLNAMALVPMFPHTLSSRPIVVDAESQIKITISPENDVSPYVSNDGQERVSIKPGGNVYTRKYHYPLHLIHPTDYNYYDTLRRKLDWEKRAAKV
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: USPB_ECOHS
Sequence: MISTVALFWALCVVCIVNMARYFSSLRALLVVLRNCDPLLYQYVDGGGFFTSHGQPNKQVRLVWYIYAQRYRDHHDDEFIRRCERVRRQFILTSALCGLVVVSLIALMIWH
What are the official names of this protein?
Universal stress protein B.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y2089_RHOP2
Sequence: MLVCIPDVLSRHEVAEFRHVMDAADWEDGRSTAGAQSAMVKRNEQLPPDGELARALGRRIIQALTANPKFVSAAVPLQIFPPLFNRYAAAGNHHFGIHVDNAVRGDPLTGLRIRTDLSVTLFLSEPDEYDGGELVIEDTYGSHEIKLPAGDCVLYPSTSLHMVTPVTRGARVASFFWLQSMIRDAHARSMIYDLDGAIQALVERLGRDDPETVKLTGIYHNLIRYWAEV
What are the official names of this protein?
PKHD-type hydroxylase RPB_2089.
Protein: AROC_SULSY
Sequence: MLRFLNAGESHGPALTAIIEGYPSNVKITTDRINKELARRQKGYGRGGRMKIEKDTVEILSGVRFGITLGSPITLVVRNKDWENWTDIMAIEGDSTNKRQILEPRPGHADLTGGIKYGFYDLRNILERASARETTTRVAVGALCKILLEDIGIKIGSYVLSIGEKKIDKSEIESISYEDRFNNAENSELRLPILGKDEEFKEYIDKAKEDGESLGGIFEVYALNVPVGLGSYSQWDTRLDGKIAQAIMSIQAIKGVEIGEGFNLAYLPGSQAHDEIFYSKERGFYRKTNRAGGLEGGMTNGEPIIVRAAMKPIPTLMRHKSLQSVNVITKEPFDAAKERSDITAVPAAAVVAESMLAFVLAREILEKFGSDNWIQIKERIEKYRQDVLNY
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RNH_CHLL3
Sequence: MQKKITIYTDGACSGNPGKGGWGAMLMYGDAVRELSGYSPATTNNRMELTAAIEALRALKEPCSVALYSDSSYVVNAFREGWLDRWTRNNWKTAAKKNVENTDLWKQILELTARHTVTFHKVKGHSDNPYNNRCDELARQAIQKKP
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_VESOH
Sequence: MAYSFTEKKRIRNNFGSRESILTEPDLLAIQIDSFNSFIQADNKIKQDIGLHNVLQSVFPITAVNGYAQIEYVDYQLKEPKFNVEECKLRGVTFASTLRVKLNLVLFDKNGSTLKKKRKVKQIIEEDVYLGQLPLMTETGTFVINGTERVVVSQLHRSPGVIFEHDKGKTHSSGKILFSSRIIPYRGSWLDFEYDHHEHLYVRIDRRRKLPVTTLLRAMGLSSEDILETFFEKTPVKLKAKSCDLSMLPIHLQRTIAEFDIVVNQHVVVEKGRRITAKHVKLLGKAGIKSINAPLEYLLDKVICADIINKDTGEILISANTITSEEVLELLNTNKVKKIEILYINSSETGAYISDTLRLDETQTEIEARMSIYHVMRPGEPATEDAVNLLFNNLFFKNDRYDLSKVGRMKLNRRLGISRETGEHVLTNDDIIRVIKLLINIKDGNDSVDDIDTLANRRVRAIGEMIENQFRIGLVRVEKAVREGLNLAETDELTPQDLINSKPVSAAVREFFGSSQLSQFMDQVNPLSGVTHKRRISALGPGGLTRERAGFEVRDVHPSHYGRLCPIETPEGPNIGLINTLAVYAKTNSYGFLETPYQIVKNGKVTKEVIYVSAIDEITHTIAQANALVDDRGKLMDDLISCRHKNEFVLVDSSEVTLIDIDSKQISSVAASLIPFLEHDDANRALMGSNMQRQAVPVLKAEKPLVGTGIERVVAKDSRVCVTAKHGGVVEAVDASRIVIRVDSKKTKANELGVDIYNLTKYSRSNQNTCINQKPLVRTGDKITFGDVLADGPSTDMGELALGQNMKIAFMPWNGYNFEDSILISEKVVQEDRYTTIHIEELTAYSRDTKLGPEEITSDIPNVSESALSKLDEVGVVYVGARVKGGDILVGKVTPKSETVLSPEEKLLRAIFGEKANNVKDSSLRIGASKSGVVIDVQVFTRDRVEKDIRALSIDAERLERIKKDIDDEFSIIDGDIFRRIRLKLLGNVLSKAIGDIRIGERLSIKLMKKFDNKDIAKFKVENATVNKEVAVLVKQAKAKKVEFEKFFKKEKAKINEGAELPPGVMKMVKVYVATRKTLQVGDKMAGRHGNKGVISRVSPVEDMPYLADGSTIDIVLNPLGVPSRMNVGQVLEVHLGYAAKGLGYKIAAILDERRPDMVKQIRVFLDKVYNLHGKKEDLTLFSNEEIIELANNLREGVPMATPVFDGIREQDIKSLLRLADLPESGQEQLYDGRTGEPFDRHVTVGYMHMLKLNHLVDDKMHARSTGPYSLVTQQPLSGKAQFGGQRFGEMEVWALEAYGAAHTLREMLTVKSDDVAGRAKMYKSIVDGKNLTESVMPESFNVLVKEIRSLGIDVELEQH
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: GCS2_ECOUT
Sequence: MPLPDFHVSEPFTLGIELEMQVVNPPGYDLSQDSSMLIDAVKNQITAGEVKHDITESMLELATDVCRDINQAAGQFSAMQKVVLQAAADHHLEICGGGTHPFQKWQRQEVCDNERYQRTLENFGYLIQQATVFGQHVHVGCASGDDAIYLLHGLSRFVPHFIALSAASPYMQGTDTRFASSRPNIFSAFPDNGPMPWVSNWQQFEALFRCLSYTTMIDSIKDLHWDIRPSPHFGTVEVRVMDTPLTLSHAVNMAGLIQATAHWLLTERPFKHQEKDYLLYKFNRFQACRYGLEGVITDPHTGDRRSLTEATLRLLEKIAPSAHKIGASSAIEALHRQVVSGLNEAQLMRDFVADGGSLIGLVKKHCEIWAGE
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: ATG11_YEAS7
Sequence: MADADEYSTAPTQQEITPLQTTATIINAISGECITTNVDFFVSLDKFKQFIARKWKIPPDQLLILLPYGNKLKPSMFKELLINRSFTLNDFYVYDRRLFSLVSKPTSTNLLTSKDSNPMNSPNSNDLTETLEYLIKNSHISQYQGSDTIMIKPMPSPLEDADVDLSRLNYHSVTSLLTTNLGWLSALEIDVHYFKSLIPDIIAHIKRIFDGLTVCSQYLKLYCFDVESLYNSNVQFLNQLVDNGMTSKWEKCFNDTLSKLTALEGDSLQKFINIESLLENEKSVKILNHSINGKLNKIKREIDENASFRDIITVNIDRLRQIFTPNESKFELEDQMAESFEVLVSEMRTRSRNVLDKEEEEFNSQEFLKSMNVMLEKDKKESVKTLFTISQALYSQIGELIDLKKSLQKHAVAILGNIAFTQMEILGIKRLLLNECNKDLELYKKYEVEFAQVEDLPLIYGLYLIEKYRRLSWFRQILSFISNFNQDLELFKQNELRTRNKWVKNFGSIATVFCEDLLSSSDFKRLNEYHSHTSPPNEDEEDENENSIANYRQDLVKVSQAIDNYMTQIKETDVSEPIIDLLSKTLFETKRFHIIYSNFKNNNNNSSNGNSISPEGSIALKSDDVVKGYKTRIKKLESLLHEFQYSDIGHWPQGVLNTHLKPFRGSATSINKKKFLGASVLLEPANISEVNIDSVSQANNHQIQELESNVDDLLHQLQLLKEENNRKSMQISEIGKKISDLEVEKTAYRETLTNLNQELARLTNEEQSHRTEIFTLNASFKKQLNDIISQDNEKIEKLTGDYYDVSKSRERLQMDLDESNKKHEQEVNLLKADIERLGKQIVTSEKSDAETNSSSMEKGEKFETIPLAEDTGRENQISAYTQTLQDRIFDIISTNIFILENIGLLLTFDNNNNIQIRRVKGLKKGTAQSNILDESTQMLDAHDNSLIKSPVFQKLKDEYELIKSVANGSEKDTQQSIFLGNITQLYDNKLYEVAVIRRFKDIETLAKKLTKENKIKRTLLERFQREKVTLRNFQIGDLALFLPTRENVNSVGSMSSSTSSLSSSFSSVDLSTPPPLDAMSIQSSPSVIHSNVINQASISGRDKNKLMRPWAAFTAFEESTRYFLKDEKGLTKGKEWFVGRIVTLEHFVADSPSNNPFRLPKGSVWFQVTAVVVSYQGV
What is the function of this protein?
Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy.  Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation, through its interaction with ATG32.  Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation.  Required for ATG9 anterograde transport from the mitochondria to the PAS.  Recruits also the ATG19-prAPE1 complex to the PAS.  Required for the Cvt vesicles completion.  Plays a significant role in life span extension (By similarity).
What are the official names of this protein?
Autophagy-related protein 11, Cytoplasm to vacuole targeting protein 9.
What is the protein family that this protein belongs to?
Belongs to the ATG11 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Note=During pexophagy, accumulates in the vacuolar membrane region, where the peroxisomes contact the vacuole.
Protein: OADC1_PSEPW
Sequence: MPKASHQDLRFAFRELLASGSCYHTASVFDPMSARIAADLGFEVGILGGSVASLQVLAAPDFALITLSEFVEQATRIGRVAQLPVLADADHGYGNALNVMRTVIELERAGVAALTIEDTLLPAQFGRKSTDLIPVEEGVGKIRAALEARVDSSLSIIARTNAGVLSTEEIIVRTQSYQKAGADAICMVGVKDFEQLEQIAGHLSVPLMLVTYANPNLHDDERLARLGVRIVVDGHAAYFAAIKATYDCLRLQRGQQNKSENLTATELSHTYTQPEDYIRWAKEYMSVDE
What is the function of this protein?
Catalyzes the decarboxylation of oxaloacetate into pyruvate.  Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate.
What are the official names of this protein?
Oxaloacetate decarboxylase 1.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family.
Protein: RL32_GRABC
Sequence: MAVPKKKTSPSRRGMRRSHQALTGEAYTECSNCGELKRPHHVCGHCGHYDGREVAAAGNSGRGLKGVVRV
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: NIKR_PSEPK
Sequence: MQRITITLDEELLDVIDRRVATQGYQGRSEAIRDLLRAGMRESEALPDDAACVAVVSYLYDHSTRELPRRLNQTLHAHHDLTRSTLHVHLDAGHCLEVSVLQGESGRIGELSRQLMVERGVEHGQVQVIPAPGQPKVR
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: PYRH_BURP1
Sequence: MPNAYKRVLLKLSGEALMGDDAFGINRATIERMVADIAEVVRLGTQLAVVIGGGNIFRGVAGGAAGMDRATADYMGMLATMMNALALQDAMRHAGIEARVQSALRMDQVVEPYIRPRAIRQLEEGKVVIFAAGTGNPFFTTDTAAALRGSEVGAEVVLKATKVDGVYSADPKKDPSATRYSSISFDEAIGRNLQVMDATAFALCRDQKLPIRVFSINKPGALKRIVQGEDEGTLVHV
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MER22_EUPRA
Sequence: DICDIAIAQCSLTLCQDCENTPICELAVKGSCPPPWS
What is the function of this protein?
Mating ciliate pheromones (or gamones) are diffusible extracellular communication signals that distinguish different intraspecific classes of cells commonly referred to as 'mating types'.  They prepare the latter for conjugation by changing their cell surface properties.
What are the official names of this protein?
Mating pheromone Er-22, Euplomone R22.
What are the subcellular locations of this protein?
Secreted.
Protein: HBBC_TREBE
Sequence: VEWTDFERATIKDIFSKLEYDVVGPATLARCLVVYPWTQRYFGKFGNLYNATAIAENAMVSKHGTTILHGLDRAVKNMDDIKNTYAELSVLHSEKLHVDPDNFKLLADCLTIVVAARFGSAFTGEVQAAFEKFMAVVVSSLGRQYH
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta-C, Beta-C-globin, Hemoglobin beta-C chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: TTL11_HUMAN
Sequence: MAAAASVTGRVTWAASPMRSLGLGRRLSLPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSGCSGGSLVADWGGGAAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEAEATAETVAEQVRVDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPPSKPKPVQGLCPHGKPRDKGRSCKRSSGHGSGENGSQRPVTVDSSKARTSLDALKISIRQLKWKEFPFGRRLPCDIYWHGVSFHDNDIFSGQVNKFPGMTEMVRKITLSRAVRTMQNLFPEEYNFYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTLQSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRIFMHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISVVIKTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSMRIEHEHELSPGVFENVPSLVDEEVKVAVIRDTLRLMDPLKKKRENQSQQLEKPFAGKEDALDGELTSAPDCNANPEAHLPSICLKQVFPKYAKQFNYLRLVDRMANLFIRFLGIKGTMKLGPTGFRTFIRSCKLSSSSLSMAAVDILYIDITRRWNSMTLDQRDSGMCLQAFVEAFFFLAQRKFKMLPLHEQVASLIDLCEYHLSLLDEKRLVCGRGVPSGGRPPHRGPPQEPSPSAQPAGDNPPPRTSCANKLSHPRHTLS
What is the function of this protein?
Polyglutamylase which modifies tubulin, generating polyglutamate side chains of variable lengths on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of tubulin.  Preferentially mediates ATP-dependent polyglutamate long side-chain elongation over the initiation step of the polyglutamylation reaction.  Preferentially modifies the alpha-tubulin tail over a beta-tail (By similarity).  Required for CCSAP localization to both spindle and cilia microtubules (PubMed:22493317).  Promotes tubulin polyglutamylation which stimulates spastin/SPAST-mediated microtubule severing, thereby regulating microtubule functions (By similarity).
What are the official names of this protein?
Tubulin polyglutamylase TTLL11, Tubulin--tyrosine ligase-like protein 11.
What is the protein family that this protein belongs to?
Belongs to the tubulin--tyrosine ligase family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton.
Protein: HTPG_CHLCH
Sequence: MSSTENNGTAVPLQEFEYKAEMKQLLDLIIHSLYTHPEIYLRELISNASDALSKARFNALTDQDMLDKDAELAIRLTLNAEEKSVVIEDSGIGMTEEELIANLGTVAKSGTLGFMQSLKEQQQQLDGNLIGQFGVGFYSVFMVTEEVTVETRSFHSNAQGYRWRSSGQGTYTIEQIDKATRGTRISFKLKEEHQEFAEEYRVEQIIKKYSNFVDFPIYLGERQLNSMTALWQRPKSELKDEEVNEFYKFVASDFNDPLDYLSISVEGMVSFKALLFLPKEAPPELMYRQSELENRGPQLYVKKVLIQNECRDLLPEYLRFIAGVVDTEDLSLNVSREMVQSSPVMAKIRQILTGKILGWFEMLAKEQPEKFKTFYKAFGPIIKIGLNTDFTNREKLIELLRFESTKTEEGEFVTLREYVERMGSEQKEIYYHSGNNRAQLLAHPNIEYFREHGIEVLLLSDPVDMFVIPSIHEFDKKPLKSIEKADCDFSQQSSNKAEPVAPNLLNPVLQAFKEALSNEVEDVVESRRLVSSPVTLVSGKDAIDSQLERMMKMMNTPMPPAKRILEVNSSHPIVRNIAGMIMADANNPLIKTVARQLYEGALFLEGSLEDATSYVTRMNELIEAATLTR
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNRF3_XENLA
Sequence: MVKDLLQNHMHPLGLCNNNDEEDLYEYGWVGVVKLEQPEMDLKPCLTVLGKAKRAVQRGATAVIFDISDNPDAVEQLNQGLDDPLKRPVVYMKGMDAIKLMNIVNKQKGARARIQHRPPRQPTEYFDMGIFLAFFVVVSLVCLILLIKIKLKQRRSQNSMNRMAVQALEKMETRKFKAKGKVSREGSCGGLDTLSSSSISDCAICLEKYIDGEELRVIPCTHRFHKRCVDPWLLQNHTCPHCRHNIIEQKKGGHGPGCVENSLSHGRQQQQQRVILPVHYPGRVQRTGPIAAYPTRTSMGPHGNPITVLTVERPVEPDLYPARTPTFLAGYRPVSLDHASSGHHCDLEHPPYPAPPAGHAFRRAKYNGRGFNNGTCYSQYETMYQHYYFQGLSFPHQQEVGGSQASRVVENGHNHSFHSGNMLYQPAPTMMHMAPPSSVESCYLHSQHQHRSVCSGYLADVPCSDSSSSSSASSAQGHASSSDSMLDCTEASNQGVYGSCSTFRSSLSSDFDPYVYRSCSPAKTGGGDAPASGGEGGTGRGRVECRSHQTFPNSPSRDRLSSCSMEMNYSSNSSLERRGAVLSSGTVPDASVSIAQSGGKDRRGPEKGCACCFQRQAGDPSSDCTTLYLGPEPHQTLGPSSSGGLYSVTSNILHRTDPGTVLGHPSRSCCLYEENHGSCYNEDYAVSIQYALAEAAAAAAAAAVAGCEAGQPIPIIPEDPGYEGGLEYVGHVSWEMEGDEEEVLYCQEGPCCMLEEETRALCRSTAKDRAGSTTGQDCHQTDTD
What is the function of this protein?
E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components (PubMed:22575959).  Along with RSPO2 and RNF43, constitutes a master switch that governs limb specification (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase ZNRF3, RING-type E3 ubiquitin transferase ZNRF3, Zinc/RING finger protein 3.
What is the protein family that this protein belongs to?
Belongs to the ZNRF3 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SACB_STRMU
Sequence: METKVRKKMYKKGKFWVVATITTAMLTGIGLSSVQADEANSTQVSSELAERSQVQENTTASSSAAENQDKTEVKETPSTNPAAATVENTDQTTKVITDNAAVESKASKTKDQAATVTKTSASTPEVGQTNEKAKATKEADITTPKNTIDEYGLTEQARKIATEAGINLSSLTQKQVEALNKVKLTSDAQTGHQMTYQEFDKIAQTLIAQDERYAIPYFNAKAIKNMKAATTRDAQTGQIADLDVWDSWPVQDAKTGEVINWNGYQLVVAMMGIPNTNDNHIYLLYNKYGDNNFDHWKNAGSIFGYNETPLTQEWSGSATVNEDGSLQLFYTKVDTSDKNSNNQRLATATVNLGFDDQDVRILSVENDKVLTPEGGDGYHYQSYQQWRSTFTGADNIAMRDPHVIEDENGDRYLVFEASTGTENYQGEDQIYNFTNYGGSSAYNVKSLFRFLDDQDMYNRASWANAAIGILKLKGDKKTPEVDQFYTPLLSSTMVSDELERPNVVKLGDKYYLFTASRLNHGSNNDAWNKANEVVGDNVVMLGYVSDQLTNGYKPLNNSGVVLTASVPADWRTATYSYYAVPVAGSSDTLLMTAYMTNRNEVAGKGKNSTWAPSFLIQVLPDGTTKVLAEMTQQGDWIWDESSRTTDTVGTLDTAYLPGENDGYIDWNVIGGYGLKPHTPGQYQPTVPSTPIHTDDIISFEVSFDGHLVIKPVKVNNDSAGRIDQSRNSGGSLNVAFNVYAGGNISVKPSQKSINNTKETKKAHHVSTEKKQKKGNSFFAALLALFSAFCVSIGFK
What are the official names of this protein?
Levansucrase, Beta-D-fructofuranosyl transferase, Sucrose 6-fructosyl transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 68 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MOAC_CUPNH
Sequence: MTQLTHFDTAGQAHMVDVGDKASTHRVAVATGTITMQPATFTLVRDGSAKKGDVIGIARVAAIMATKRTADLIPLCHPIGLTKVAVEFALDEATATVACTVRTETRGQTGVEMEALTGVQVALLTIYDMCKAVDRGMVIGNVKLLEKHGGKSGDWVAAG
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: COT2_RAT
Sequence: MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGSQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
What is the function of this protein?
Ligand-activated transcription factor.  Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro).  Regulation of the apolipoprotein A-I gene transcription.  Binds to DNA site A.  May be required to establish ovary identity during early gonad development.
What are the official names of this protein?
COUP transcription factor 2, COUP-TF2, Apolipoprotein A-I regulatory protein 1, ARP-1, COUP transcription factor II, COUP-TF II, COUPb, Nuclear receptor subfamily 2 group F member 2, Ovalbumin upstream promoter beta nuclear receptor.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: IF1_OCEIH
Sequence: MAKDDVIEVEGTVTDTLPNAMFKVELENGHTVLAHVSGKIRMHFIRILPGDKVTVELSPYDLTRGRITYRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH601_SYNP6
Sequence: MAKRIIYNENARRALEKGIDILAEAVAVTLGPKGRNVVLEKKFGAPQIINDGVTIAKEIELEDHIENTGVALIRQAASKTNDAAGDGTTTATVLAHAVVKEGLRNVAAGANAILLKRGIDKATNFLVEQIKSHARPVEDSKSIAQVGAISAGNDFEVGQMIADAMDKVGKEGVISLEEGKSMTTELEVTEGMRFDKGYISPYFATDTERMEAVFDEPFILITDKKIGLVQDLVPVLEQVARAGRPLVIIAEDIEKEALATLVVNRLRGVLNVAAVKAPGFGDRRKAMLEDIAVLTGGQLITEDAGLKLDTTKLDQLGKARRITITKDNTTIVAEGNEAAVKARVDQIRRQIEETESSYDKEKLQERLAKLSGGVAVVKVGAATETEMKDRKLRLEDAINATKAAVEEGIVPGGGTTLAHLAPQLEEWATANLSGEELTGAQIVARALTAPLKRIAENAGLNGAVISERVKELPFDEGYDASNNQFVNMFTAGIVDPAKVTRSALQNAASIAAMVLTTECIVVDKPEPKEKAPAGAGGGMGDFDY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDHE_YERP3
Sequence: MSIRIVPKDQLGKQREKGTTAGNIPPLLFANLKSLYTRRTERLQQLALDNPLADYLDFAAKITEAQQKALHDHPLVLDMQAELVQSAASGKPPLDGSVFPRTEHWRKLLSALIAELRHDAPDHILAVLDNLDKASVHELELYADALLNRDFSQVGSEKAPFIWAALSLYWAQMASQIPGKARAEYGEHRQFCPVCGSIPVSSVVHIGTHNGLRYLHCNLCESEWHVVRIKCSNCEQTRDLNYWSLDSELAAVKAESCGDCGTYLKILYQEKDPQVEAVADDLASLILDAKMEGEGFARSSINPFLFPGE
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE homolog.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_MAGMM
Sequence: MRWMKIMSEDMKQEQSGEGRGGRGGPARPLASARRPFFRRRKVCPFCADKGLKIDYKDPKMLSRYITERGKMVPSRITGVCAPHQRKLSVAIKRARNIALLPFIVK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.