PharMolix/UniProtQA huggingface dataset:
Protein: ANXA1_BOVIN
Sequence: MAMVSEFLKQAWFIENEEQEYIKTVKGSKGGPGSAVSPYPTFNPSSDVEALHKAITVKGVDEATIIEILTKRNNAQRQQIKAAYLQEKGKPLDEVLKKALLGHLEEVVLALLKTPAQFDAEELRAAMKGLGTDEDTLNEILASRTNREIREINRVYREELKRDLAKDIASDTSGDYEKALLSLAKGDRSEELAVNDDLADSDARALYEAGERRKGTDVNVFITILTTRSYPHLRRVFQKYSKYSKHDMNKVLDLELKGDIEKCLTVIVKCATSQPMFFAEKLHQAMKGIGTRHKTLIRIMVSRSEIDMNDIKACYQKLYGISLCQAILDETKGDYEKILVALCGRD
What is the function of this protein?
Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades.  Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors.  Promotes rearrangement of the actin cytoskeleton, cell polarization and cell migration.  Promotes resolution of inflammation and wound healing.  Acts via neutrophil N-formyl peptide receptors to enhance the release of CXCL2.
What are the official names of this protein?
Annexin A1, Annexin I, Annexin-1, Calpactin II, Calpactin-2, Chromobindin-9, Lipocortin I, Phospholipase A2 inhibitory protein, p35.
What is the protein family that this protein belongs to?
Belongs to the annexin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell projection, cilium. Basolateral cell membrane. Lateral cell membrane. Cell membrane; Peripheral membrane protein. Apical cell membrane. Membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Secreted. Secreted, extracellular space. Cell membrane; Peripheral membrane protein; Extracellular side. Early endosome. Cytoplasmic vesicle membrane; Peripheral membrane protein. Secreted, extracellular exosome. Cytoplasmic vesicle, secretory vesicle lumen. Cell projection, phagocytic cup. Note=Colocalizes with actin fibers at phagocytic cups. Secreted, at least in part via exosomes and other secretory vesicles. Detected in exosomes and other extracellular vesicles. Secretion is increased in response to wounding and inflammation (By similarity). Alternatively, the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in the protein translocation from the cytoplasm into ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion (By similarity). Detected in gelatinase granules in resting neutrophils. Neutrophil adhesion to endothelial cells stimulates secretion via gelatinase granules, but foreign particle phagocytosis has no effect. Displays calcium-dependent binding to phospholipid membranes (By similarity).
Protein: ROAA_HUMAN
Sequence: MSEAGEEQPMETTGATENGHEAVPEASRGRGWTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPESPTEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQQYGSGGRGNRNRGNRGSGGGGGGGGQSQSWNQGYGNYWNQGYGYQQGYGPGYGGYDYSPYGYYGYGPGYDYSQGSTNYGKSQRRGGHQNNYKPY
What is the function of this protein?
Binds single-stranded RNA.  Has a high affinity for G-rich and U-rich regions of hnRNA.  Also binds to APOB mRNA transcripts around the RNA editing site.
What are the official names of this protein?
Heterogeneous nuclear ribonucleoprotein A/B, hnRNP A/B, APOBEC1-binding protein 1, ABBP-1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Protein: ARGB_SOLUE
Sequence: MKLLVKLGGTLLDSAASRDSLCLQIAAARAAGHEVTVVHGGGKQMTRYLTDRGIESRFVGGLRVTSPDTIDAVLKVFAGSVNHELVANLNRAGALAVGLSGIDSFLVEAEQMDPELGAVGRVTGSNPALLHLLTANGYVPVVACVAGDRLGQIYNVNADQMAVACASAFGACRLIFLTDVDGVMDNSNRVRPVLTAAESRQLIDEGIATGGMQAKLNAALSALADGVQQVRIAPGAAPGALQRILAGEEIGTKMVTA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRG_ARATH
Sequence: MGKWRAVAALLLRNQLLNSSKRLNLSSSPCVSKHPTIGLASRFLNFRHFSAFPSPISIYNNDSDSGSNDAYQNYEFGTEAEEALGKIPIKAYFLSTSIDLKAMQAENLCNVVPPTSRSTNYIALKFSDFTPSGIYSLDERESVSNCKFMVVFQYGSAILFNVDDNDVDRYLDIVRRHASGLLTEMRKDDYAVKEKPLLIEEMKGGPDYIVLKTLDTNSIRIIGSVLGQSIALDYSVSQVNKLVEEFADINRSMAKTGTFTMTRKKLFQLVGKANSNIADVILKVGLFERSEIAWREARYAQIYEYLREEYEISQRFGDLDYKLKFIEHNIHFLQEVMQNRQSDLLEWCIIFLLAIENAIGIYEIVRESAGASL
What is the function of this protein?
Required for the maintenance of mitochondrial structure (PubMed:21984726).  Positive regulator of cell division and endoreduplication but negative regulator of cell expansion in the postembryonic root meristem, thus leading to the promotion of root growth (PubMed:21984726).
What are the official names of this protein?
Protein RETARDED ROOT GROWTH, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RMD1/sif2 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein. Mitochondrion.
Protein: RBS1_AMAHP
Sequence: MASSMLSNAAMATTAATAGAQASMVAPFNGLKSFATFPITKKSSNDFSSLPSNGGRVQCMQVWPPVGKKKFETLSYLPPLSDAQLLAQVQYLLNKGWIPCIEFELEHPFVYRENHRSPGYQDGRYWTMWKLPMYGCTDPAQVLNEVEEAKKAYPSAFIRIIGFDNKRQVQCVSFIAYKPAGGL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic 1, RuBisCO small subunit 1.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TM269_HUMAN
Sequence: MVLGLFSIIFSFSRKCHYASRMLLVSFLLDMAVRAMTSHINICSKLGAELNDFAVFTTFGLASALLLGVDGLLSGILAIIYVSAASFHLCFYSPGVPSTYKGLPCPYASCILASTSLLTKGNRFILCCMASLMILFMMDQSYYPYDKILESENWKKLVYIGGVIMLFFSPLSLSAFYCLMWSLSYIFFPDALWGKAACLSPQH
What are the official names of this protein?
Transmembrane protein 269.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DAPE_YERPY
Sequence: MICPVIELAQQLIKRPSLSPSDAGCQEIMIQRLAAIGFTIEPMNFGDTLNFWAWRGEGETLAFAGHTDVVPTGDESHWHSPPFEPTIRDGMLYGRGAADMKGSLAAMIVAAERFVAAHPDHKGRLAFMITSDEEAKATNGTVKVVEALMARHERLDYCLVGEPSSTDRVGDIVKNGRRGSITANLRIHGVQGHVAYPHLADNPVHRAMPALNELVATQWDEGNAFFPATSMQIANLQAGTGSNNVIPGEFYVQFNFRFSTELTDSLIKQRVAALLDRHQLDYTLEWVLSGQPFLTAKGALVDAVVNAVKHYTEITPQLLTTGGTSDGRFIALMGAQVVELGPVNATIHKVNECVSAADLQLLSRMYQKIMEQLIA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: FKBP3_VICFA
Sequence: AAEVAPCELTVAPSGLSFCDKVVGTGPQAVKGQLIKAHYVGRLEN
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
FKBP-type peptidyl-prolyl cis-trans isomerase, chloroplastic, PPIase, Rotamase, VfFKBP13.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: PRIPO_MOUSE
Sequence: MLRKWEARVKQIEERASHYERKPLSSVYRPRLAKPEEPSSIWKLFHRQNQAFNFVKSCKESVHVFALECKRGNGQRIYLVTSYAQLWFYYKTRKTLLHCYEVIPENAVCKLYFDLEFNKLANPGADGKMMVALLIQHVCKALEEFYNVQCSAEDVFNLDSSTEEKFSRHLIFQLHNVAFKDNRHAGNFVRKILQPALHLIAEDDEAKVPEAVGQDASGFSVTPLKQEISEAREKVGLPKQCDPDLSFLVVKNHMGEKCLFVDLGVYTKNRNFRLYQSSKIGKCVSLEVAEDNRFIPKQSKDISEENQYFLSSLVSNVRFSDTLRVLTCHPSQTKRKRAECFNSTGTSVESIEGFQGSPYPEVDQFVLSLVNKHDIKGGIRRWNYFFPEELLVYDICKYRWCENIGRAHKSNNIMILVDLKNEVWYQKCHDPVCKAQNFKSTCSPLPTEVSLLFLLKDEDFTSGETDDTSTSLTKDSQTPPSCNLSAGGLSAAAWDDEDDALFLEATEDAEFADAADKSLGSMDDIPDELIIEALQNS
What is the function of this protein?
DNA primase and DNA polymerase required to tolerate replication-stalling lesions by bypassing them (PubMed:26926109, PubMed:29073063).  Required to facilitate mitochondrial and nuclear replication fork progression by initiating de novo DNA synthesis using dNTPs and acting as an error-prone DNA polymerase able to bypass certain DNA lesions (By similarity).  Shows a high capacity to tolerate DNA damage lesions such as 8oxoG and abasic sites in DNA (By similarity).  Provides different translesion synthesis alternatives when DNA replication is stalled: able to synthesize DNA primers downstream of lesions, such as ultraviolet (UV) lesions, R-loops and G-quadruplexes, to allow DNA replication to continue (By similarity).  Can also realign primers ahead of 'unreadable lesions' such as abasic sites and 6-4 photoproduct (6-4 pyrimidine-pyrimidinone), thereby skipping the lesion (By similarity).  Also able to incorporate nucleotides opposite DNA lesions such as 8oxoG, like a regular translesion synthesis DNA polymerase (By similarity).  Also required for reinitiating stalled forks after UV damage during nuclear DNA replication (By similarity).  Required for mitochondrial DNA (mtDNA) synthesis and replication, by reinitiating synthesis after UV damage or in the presence of chain-terminating nucleotides (PubMed:29073063).  Prevents APOBEC family-mediated DNA mutagenesis by repriming downstream of abasic site to prohibit error-prone translesion synthesis (PubMed:26926109).  Has non-overlapping function with POLH (By similarity).  In addition to its role in DNA damage response, also required to maintain efficient nuclear and mitochondrial DNA replication in unperturbed cells (By similarity).
What are the official names of this protein?
DNA-directed primase/polymerase protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase small subunit family.
What are the subcellular locations of this protein?
Nucleus. Mitochondrion matrix. Chromosome. Note=Present in the nucleus, but a larger fraction is localized inside mitochondria. Associates with nuclear chromatin during the G1 and S phases of unperturbed cell cycles. Recruited to stalled replication forks following interaction with RPA1.
Protein: CRYAA_ANAPL
Sequence: RALGPLIPSRLFDQFFGEGLLEYDLLPLFSSTISPYYRQSLFRSVLESGISEVRSDRDKFTIMLDVKHFSPEDLSVKIIDDFVEIHGKHSERQDDHGYISREFHRRYRLPANVDQSAITCSLSGDGMLTFSGPKVPSNMDPTHSERPIP
What is the function of this protein?
Contributes to the transparency and refractive index of the lens.  May act as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions.
What are the official names of this protein?
Alpha-crystallin A chain.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to the nucleus during heat shock.
Protein: SSRP_EHRCJ
Sequence: MDVIIENRKVRFNYFIIQEFDAGIVLIGSEVKSLRQRKVSIAEAYVTEKNMELWLCNLHISEYNHASTKNHNPTRPRKLLLRKKQIYKISGNIKNDGFTVVPLSLYFNEKGLAKAKIVIVKGKKLHDKRETIKTRDWNREKSRVLRGN
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: DLTC_BACHK
Sequence: MAEFKEQVLDILEEVCENDIVKENLDVQLFEEGILDSFAVVSLLVEFQERLDIEVSISDFDRDEWATPNMVIKKLEEIR
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSH1_PECCP
Sequence: MIPDISEALSWLEKHPLAVKGIQRGIERETLRVTANGHLATTGHPEILGSALAHPWITTDFAEALLEFITPVDNDVDHLLTFLRDIHRHVSRNLGDERMWPLSMPCFIDSEQNIELAQYGSSNIGRFKTLYREGLKNRYGALMQTISGVHYNFSLPLSFWQAREGVADAESGKKAISAGYFRLIRNYYRFGWVIPYLFGASPAICSSFLKGRETALPFERTEKGMLYLPYATSLRLSDLGYTNKSQSNLGITFNDLDTYVAALKRAIKTPSEEYAQVGMKKDGRYLQLNTNVLQIENELYAPIRPKRVTRAGETPSDALLRGGIEYIEVRSLDINPFSPTGVSESQVRFLDLFLIWCALADAPEMSADELLCTRKNWNRVILEGRKPGQTVGMRCETIQQPIAEVGKSLFADLRRVAEVLDAENSQPHYQQVCDELLVGFDDPETTFSGRLLTLMKQEGNGSVGLSLAEEYRKMLSSEPLQVLTEEQLAAASEHSWQRQRQIESEDTMSFDDYLAAN
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: RSMJ_STUS1
Sequence: MSASNSLVRVEPLAPSFAAVAGQWAQRLGLPQELAEAEFALQVGEAGLQLQLLEAQAPGPVRVDFVEGAAAHRRQFGGGSGQMIAKAVGIQPGIRPRVLDATAGLGRDAFVLATLGCEVSLIERQPLIAALLDDGLSRAAADADVAAIAARMRLLEGNAIELMQHWRGEPPQVIYLDPMFPHRDKSALVKKEMRLFRPFVGDDLDAPALLSAALELASHRVVVKRPRKAPAIDGSKPGYSLEGKSSRYDIYPKKKLQA
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
Protein: VIP_MACMU
Sequence: HSDAVFTDNYTRLRKQMAVKKYLNSILN
What is the function of this protein?
VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.
What are the official names of this protein?
Vasoactive intestinal peptide, VIP, Vasoactive intestinal polypeptide.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: TMCO1_BOVIN
Sequence: MSTMFADTLLIVFISVCTALLAEGITWVLVYRTDKYKRLKAEVEKQSKKLEKKKETITESAGRQQKKKIERQEEKLKNNNRDLSMVRMKSMFAIGFCFTALMGMFNSIFDGRVVAKLPFTPLSYIQGLSHRNLLGDDTTDCSFIFLYILCTMSIRQNIQKILGLAPSRAATKQAGGFLGPPPPSGKFS
What is the function of this protein?
Calcium-selective channel required to prevent calcium stores from overfilling, thereby playing a key role in calcium homeostasis.  In response to endoplasmic reticulum (ER) overloading, assembles into a homotetramer, forming a functional calcium-selective channel, regulating the calcium content in endoplasmic reticulum store.  Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes.  The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions.  Within the MPT complex, the GEL subcomplex may mediate insertion of transmembrane regions into the membrane.
What are the official names of this protein?
Calcium load-activated calcium channel, CLAC channel, GEL complex subunit TMCO1, Transmembrane and coiled-coil domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the TMCO1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=The first transmembrane region is required for localization to the endoplasmic reticulum.
Protein: FCF1_PONAB
Sequence: MGKQKKTRKYATMKRMLSLRDQRLKEKDRLKPKKKEKKDPSALKEREVPQHPSCLFFQYNTQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKCIPCITDCVMAEIEKLGQKYRVALRIAKDPRFERLPCTHKGTYADDCLVQRVTQHKCYIVATVDRDLKRRIRKIPGVPIMYISNHRYNIERMPDDYGAPRF
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
rRNA-processing protein FCF1 homolog.
What is the protein family that this protein belongs to?
Belongs to the UTP23/FCF1 family. FCF1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: EFG_LIMF3
Sequence: MANKREYPLEKTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETHDGASQMDWMEEEKERGITITSAATTAVWKDTRINIIDTPGHVDFTVEVERALRVLDGAVTVLDAQAGVEPQTETVWRQADDFNVPRLVFANKMDKMGANFDYSVKTIKERLNVTPLPIQMPIGAEDEFAGVIDLVKMVAYIYDEDKLGENWDTVEIPADMKDEAESRHDAMIETLADVNDDIMEKYLEGAEISVDEIKAAIRQATLDQELFPVMAGSAYKDKGIQMMLDAVLDYLPSPVDVKPFVAHDEEGNAIELTAGDDKPFAALAFKIATDPFVGRLTFLRVYTGSLKSGSYVLNATKGKRERIGRLLQMHSNQQNEISEVFSGDIAAAIGLKNTTTGDSLTDPDHPLQLESMDFPEPVIQVSVEPKSKADQDKMDKGLQKLAEEDPTFKAETNPETGETLIAGMGELHLDIIVERLRREFNAEVTVGKPQVSYREAFTKQVSAQGKFVRQSGGKGQYGDVWIEFTPLEEGAGFEFEDAIVGGVVPREYIPAVEQGLKEAMENGVLAGYPLVDLHAKLYDGSYHEVDSSEAAFKVAASLALRNAAPKGGAVILEPIMKVDIVAPEDNLGDVMGHVTARRGSIDGMEERGNAQLVHSFVPLSEMFGYATTLRSATQGRGTFTMTFDHYSAVPKSIQEEIIEKNGGK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y864_THEVO
Sequence: MDVKIIWHGHACFSIEGKKNVLIDPFLTGNPMAKVKAEDLNPDIILVTHGHYDHAADAVSISKRTGAPVLSVFELSEIFKESGINTIDINPGGTVEFEGVSIKATIATHSSSYDGRYAGNPVGYVIDIGRKIYHAGDTGYFKDMELIGSVDRPEISLLPIGGHYTMDVDGAVEALKMLKSPIAIPMHYNTFDVIKADPLRFKNLAAAVGTYVIVPKVEEPVEL
What are the official names of this protein?
UPF0173 metal-dependent hydrolase TV0864.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: DNAA_SYNFM
Sequence: MEQEWLQVRKKLQRSLSKGQYDLWVSTLEFLGIEDGNLILGCQNRFHIEWLREKLEAKLLPIASQHFRGVRKLEYRVAQGCAAGAPEIEGAGPRQIAFSDVVKCVGPAFNPRFTFDHFVVGGCNQFAYAAAMGMANNQQLYNQSVYLLSDTGLGKSHLTHAVGNYLRNRKPELRVQYVTTEQFANEMIFSLKNGNMEAFKNKFRTGCDVLLLEKIEFLSGKEKIQKELVYTLDELMDRGKTVLCTGNAYPKDIPKLNSELQSRLGGGLLAPIDKPDFKTRIEIIKRKSHTENIRVPMEVVEYLADRITGDVRQLESCLVGLMAKSNILRTPITLDLAREVSQTMLDQLPKISVEQIQKIICANFRITLEELRSTSRRKQVALARKIGIYLSREYTTESLQSIGKSFQRSHSSVLYAVNEVQKGMGEANGRLKREVEYLSRRLETSCLSES
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_SHISS
Sequence: MAKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLDNAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTAKSDEEGRALLAAFDFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RPOZ_NOCSJ
Sequence: MSGPTIAAEGVTNPPIDELLTKTDSKYKLVLYSAKRARQINAYYSQLGEGLLEYVGPLVDTHVQEKPLSIALREINEDLLTCEDVDPAELAAEEAAAQAAAADAGSSFSE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: YR738_MIMIV
Sequence: MSLQKHGLLFNNNKFSDCKLVLDDGNVQVTLNVHKCLLYMNSLYFQAMFDNFKEQEYSEIKIRVQNSQIATDVIKSFYEKSNVINADWQYQLDYAIETKFFGVEYVLDKNIIVPYIYFDLFVDKIELIGYNNTTLNMILNNLPLDYDLDKFPTDFLEGLLVSSTEYDIFLSNKHCFYVWSVTDNKFTYSKEIPLELYYSYLDNDKIYKFTEHNSLICFNKKTDRHKSILLYDNDKIIKFDTEGVIYYLPENNQIILSHVERTTTGCDYKISLFCLETKQLIRTFHSRNYFGNEIILQISVSHDKIIVFGDDVQVKNFSSGVCLFTINQNESGVCIACDPEWSYFAIGSEDYDTEDQKITIYDLSNGNKVKTLNHRDSIRDILWTSKYIIAHNNENIYFYETNNYELVKKLDYKNNGLIKKIDCFDDSEFLYVLTNNSKMFQINMDSLENTDSNNISTEICFTQIGRFCDFKTIKNSNYHKSKLIKKTLEQRRRMDKN
What are the official names of this protein?
Putative BTB/POZ domain-containing protein R738.
What is the protein family that this protein belongs to?
Belongs to the mimivirus BTB/WD family.