PharMolix/UniProtQA huggingface dataset:
Protein: ENV_SIVTN
Sequence: MKNLIGITLILIITILGIGFSTYYTTVFYGVPVWKEAQPTLFCASDADITSRDKHNIWATHNCVPLDPNPYEVTLANVSIRFNMEENYMVQEMKEDILSLFQQSFKPCVKLTPFCIKMTCTMTNTTNKTLNSATTTLTPTVNLSSIPNYEVYNCSFNQTTEFRDKKKQIYSLFYREDIVKEDGNNNSYYLHNCNTSVITQECDKSTFEPIPIRYCAPAGFALLKCRDQNFTGKGQCSNVSVVHCTHGIYPMIATALHLNGSLEEEETKAYFVNTSVNTPLLVKFNVSINLTCERTGNNTRGQVQIGPGMTFYNIENVVGDTRKAYCSVNATTWYRNLDWAMAAINTTMRARNETVQQTFQWQRDGDPEVTSFWFNCQGEFFYCNLTNWTNTWTANRTNNTHGTLVAPCRLRQIVNHWGIVSKGVYLPPRRGTVKCHSNITGLIMTAEKDNNNSYTPQFSAVVEDYWKVELARYKVVEIQPLSVAPRPGKRPEIKANHTRSRRDVGIGLLFLGFLSAAGSTMGAASIALTAQARGLLSGIVQQQQNLLQAIEAQQHLLQLSVWGIKQLQARMLAVEKYIRDQQLLSLWGCANKLVCHSSVPWNLTWAEDSTKCNHSDAKYYDCIWNNLTWQEWDRLVENSTGTIYSLLEKAQTQQEKNKQELLELDKWSSLWDWFDITQWLWYIKIAIIIVAGLVGLRILMFIVNVVKQVRQGYTPLFSQIPTQAEQDPEQPGGIAGGGGGRDNIRWTPSPAGFFSIVWEDLRNLLIWIYQTFQNFIWILWISLQALKQGIISLAHSLVIVHRTIIVGVRQIIEWSSNTYASLRVLLIQAIDRLANFTGWWTDLIIEGVVYIARGIRNIPRRIRQGLELALN
What is the function of this protein?
The gp120-gp41 heterodimer allows rapid transcytosis of the virus through CD4 negative cells such as simple epithelial monolayers of the intestinal, rectal and endocervical epithelial barriers.  Both gp120 and gp41 specifically recognize glycosphingolipids galactosyl-ceramide (GalCer) or 3' sulfo-galactosyl-ceramide (GalS) present in the lipid rafts structures of epithelial cells.  Binding to these alternative receptors allows the rapid transcytosis of the virus through the epithelial cells.  This transcytotic vesicle-mediated transport of virions from the apical side to the basolateral side of the epithelial cells does not involve infection of the cells themselves (By similarity).
What are the official names of this protein?
Envelope glycoprotein gp160, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein gp41]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Surface protein gp120]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Host endosome membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag (By similarity).
Protein: AROC_KORVE
Sequence: MLRFQTAGESHGEALVATLTGVPAGLPIDQAFLDRELWRRQQGFGRGGRMKIERDTAHILSGVHHGKTIGSPIAILIRNNDWKNWQESLPVEEGDSAKHKPVKSPRPGHADLAGALKYNFPEARYVLERASARETTARVAAGAIAKLLLRQIGADVLSHVIAVGTARLENTEVQWEKLVELAQRDNVLLGCVDPEAEQRMKEQVDQVLRTGDTVGGVFEVVAHNLPPGLGTYVEWDRRLDGLLAMAVMSLQAVKAVEIGEGVSVAATFGSGAQDEIGYEREHESKFTGFTRTSNHAGGIEGGVSNGQDILVRGYLKPISTLRRPLGSVDFATREPLKAAYERSDVCVVPAAGIAAEAMVAITLAGCALEKFGGDSLVEFKRNYEGYCQQLQSF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RL18_MYCGA
Sequence: MKQVNMNRNERRQMRHKRVIKKIRRIDNDRPVMIVVKSNSHISAQVWDFNQNKIIASSSSVSLDLVNGNKENAAVVGTDIANKLLKMKIDEITFDHGGSKYHGRIAALADAARKAGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: CTSR_STAAM
Sequence: MHNMSDIIEQYIKRLFEESNEDVVEIQRANIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQAYYIIDGLLDKMLINEREAKMIQAVIDRETLSMDMVSRDIIRANILKRLLPVINYY
What is the function of this protein?
Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
What are the official names of this protein?
Transcriptional regulator CtsR.
What is the protein family that this protein belongs to?
Belongs to the CtsR family.
Protein: RL6_HELPG
Sequence: MSRIGKRIIEIPSSVQASVEGSKLLFKNSKEKHELETHNRVKITLENNQLSFQPVGEDAQSRAYWGTYGALANNIVTGLSTGFSKTLEVNGVGYKVALGNKTLDLSLGFSHPVKYPIPAGIEMVVEKNTITIKGSDKQKVGQVAAEIRSFRPPEPYKGKGVKYSDEVIIRKAGKTAKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: HOLIN_BPML5
Sequence: MSPKIRQTIYLLGTAAPALLGIVLIWGGLDAESAADLGDIIAGVVSILVSGAPAVAAGTVRSQRKDGTLSTSPVDQVTKGVEQVLAARQSAEAEVAKVKQALETAVSGSLPQLGPLATQILNVADDTVWRP
What is the function of this protein?
Accumulates harmlessly in the cytoplasmic membrane until it reaches a critical concentration that triggers the formation of micron-scale pores (holes) causing host cell membrane disruption and endolysin escape into the periplasmic space.  Determines the precise timing of host cell lysis.  Participates with the endolysin protein in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles from the host cell.
What are the official names of this protein?
Holin, Gene product 11, gp11.
What is the protein family that this protein belongs to?
Belongs to the Mycobacterium phage D29 holin family.
What are the subcellular locations of this protein?
Host cell inner membrane; Multi-pass membrane protein.
Protein: NAGK_YERPB
Sequence: MYYGFDMGGTKIELGVFDENLQRIWHKRVPTPREDYPQLLQILRDLTEEADTYCGVQGSVGIGIPGLPNADDGTVFTANVPSAMGQPLQADLSRLIQREVRIDNDANCFALSEAWDPEFRTYPTVLGLILGTGVGGGLIVNGSIVSGRNHITGEFGHFRLPVDALDILGADIPRVPCGCGHRGCIENYISGRGFEWMYSHFYQHTLPATDIIAHYAAGEPKAVAHVERFMDVLAVCLGNLLTMLDPHLVVVGGGLSNFEKIYQELPKRLPAHLLRVARLPRIEKARYGDSGGVRGAAFLHLAEK
What is the function of this protein?
Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
What are the official names of this protein?
N-acetyl-D-glucosamine kinase, GlcNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NagK subfamily.
Protein: MNME_STRPG
Sequence: MSITKEFDTITAISTPLGEGAIGIVRLSGTDALAIAQSVFKGKSLEQVASHTINYGHIIDPKTGTIIDEVMVSVMLAPKTFTRENVVEINTHGGIAVTNEILQLLIRQGARMAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMTIAVKQLDGSLSQLINDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLREKTQEFQSLLENLLRTAKRGKILREGLSTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNIKGVPLKLVDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTDQDRALLNLSQDSNRIILLNKTDLEQKIELEQLPDDYIPISVLTNQNINLIEDRINQLFFDNAGLVEQDATYLSNARHISLIEKAVQSLEAVNDGLALGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_XANCB
Sequence: MIRRLQDSGDLVRAFPRVHFVGIGGTGMSGIAEVMLTLGYEVSGSDNADNAATRRLAKLGARVMRGHSAANVLGTDCVVVSSAIREDNPELMEARSQRIPIMPRAAMLAELMRFRRGIAVAGTHGKTTTTSLAAAVLSEGGLDPTFVIGGQLLAAGANAKLGGGQWLVAEADESDGSFLRLNPLMAVITNIDADHLENYGNDFARVQAAFAEFLQRLPFYGLALLCIDDPEVAALAGKTPRHVMSYGMSENADVRAEDVVQDGPRMRFTLRLPEGTTTPVTLALPGRHNVLNALAAAAIGWQLGVAPDTIARALENFAGIGRRFNDLGEVTTASGARVRVVDDYGHHPRELEAVFAAARGGWPDKRLVVAFQPHRYSRTRDQFDAFAAVLSTVDALVLSEVYPAGEAPIPGADSRALARAIRARGRSEPVVVGQVAGLSEVLPDVLQDGDLLLMMGAGDIGYVAQQIVTDGFVGAPA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WALK_STAA3
Sequence: MKWLKQLQSLHTKLVIVYVLLIIIGMQIIGLYFTNNLEKELLDNFKKNITQYAKQLEISIEKVYDEKGSVNAQKDIQNLLSEYANRQEIGEIRFIDKDQIIIATTKQSNRSLINQKANDSSVQKALSLGQSNDHLILKDYGGGKDRVWVYNIPVKVDKKVIGNIYIESKINDVYNQLNNINQIFIVGTAISLLITVILGFFIARTITKPITDMRNQTVEMSRGNYTQRVKIYGNDEIGELALAFNNLSKRVQEAQANTESEKRRLDSVITHMSDGIIATDRRGRIRIVNDMALKMLGMAKEDIIGYYMLSVLSLEDEFKLEEIQENNDSFLLDLNEEEGLIARVNFSTIVQETGFVTGYIAVLHDVTEQQQVERERREFVANVSHELRTPLTSMNSYIEALEEGAWKDEELAPQFLSVTREETERMIRLVNDLLQLSKMDNESDQINKEIIDFNMFINKIINRHEMSAKDTTFIRDIPKKTIFTEFDPDKMTQVFDNVITNAMKYSRGDKRVEFHVKQNPLYNRMTIRIKDNGIGIPINKVDKIFDRFYRVDKARTRKMGGTGLGLAISKEIVEAHNGRIWANSVEGQGTSIFITLPCEVIEDGDWDE
What is the function of this protein?
Member of the two-component regulatory system WalK/WalR that regulates genes involved in cell wall metabolism, virulence regulation, biofilm production, oxidative stress resistance and antibiotic resistance via direct or indirect regulation of autolysins.  Functions as a sensor protein kinase which is autophosphorylated at a histidine residue in the dimerization domain and transfers its phosphate group to the conserved aspartic acid residue in the regulatory domain of WalR.  In turn, WalR binds to the upstream promoter regions of the target genes to positively and negatively regulate their expression.
What are the official names of this protein?
Sensor protein kinase WalK.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS10_MYCSJ
Sequence: MAGQKIRIRLKAYDHEAIDASARKIVETVTRTGASVVGPVPLPTEKNVYCVIRSPHKYKDSREHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RS2_RIPO1
Sequence: MPVVSLAELLESGVHFGHQTRRWNPKMSPYIYTARNGVHIIDLVQTAQLMENAYEYVRKSSEQGKRFLFIGTKRQAAGIIAQEASRCGANYVNQRWLGGMLTNWETIKGRVERLKELESMEENGAISRRPKKEAAVLRRELGKLDKYLGGIKTMRKLPDVVVIVDQRREYNAISECQKLGIPIISMLDTNCDPDFADIPIPANDDAIRSIKLILGKLADAIYEGRHGQLDSEQDYEDFDESISDEYDDYEDEEEYEEQDLEVDASEDE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: SYR_MYCPN
Sequence: MLFINTDLQECLNALNLEFDEHKELVKLVKNNSFSGFASTVVFHLKGVNQKETAQQIAAWLLKHKKAHYRRVFVANNNFINFEISPQKYLDFLKTKPTFAPKPTKVLIEWVSANPTGELHLGHVRNAFFGHVLNNLMVFLGFQTVREYWVNDYGQQARVFGFSVYQALHLQQNIKVTPHPDGYEGELVDSIAKTITGIPLDKLSFEEFLQQPFLDQLLADCTAKVLEVIKQDLATIHIHFDSWKFESQVVKETDYKKLLTQFKDEAHYEKDGAIWLKTTLYGDDKDRVLVRQDNRPSYFGTDVAYHLDKAARGFDLLYDIWGSDHEGHIKRMHCVYEGLKIHQKCQLKITALQLVMLYKNKEIVRLSKRAGNVITIKQMLQMLSEDAARWFMLSQTNNSIIKIDLDTANLQNSSNPVYYVQYAYARMCSVLKVVDQAALAQVNDCSLLTHEKEIALLDQLVYFKSLLEKVQVSHELHLLTNYLYETATLFHSWYKACKINDPAQYNLTQQRLLLLQSLHHVFGQLLQILNITAPQQM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBC23_PONAB
Sequence: MAEGEDVLPLPTSSGDGWEKDLEEALEAGGCDLETLRNIIQGRPLPADLRAKVWKIALNVAGKGDSLASWDGILDLPEQNTIHKDCLQFIDQLSVPEEKAAELLLDIESVITFYCKSRNIKYSTSLSWIHLLKPLVHLQLPRSDLYNCFYAIMNKYIPRDCSQKGRPFHLFRLLIQYHEPELCSYLDTKKITPDSYALNWLGSLFACYCSIEVTQAIWDGYLQQADPFFIYFLMLIILVNAKEVILTQESDSKEEVIQFLENTPSSLNIEDIEDLFSLAQYYCSKTPASFRKDNHHLFGSTLLGIKDDDADLSQALCLAISVSEILQANQLQGEGVRFFVVDCRPAEQYNAGHLSTAFHLDSDLMLQNPSEFAQSVKSLLEAQKQSIESGSIAGGEHLCFMGSGREEEDMYMNMVLAHFLQKNKEYVSIASGGFMALQQHLADINVDGPENGYGHWIASTSGSRSSINSVDGESPNGSSDRGMKSLVNKMTVALKTKSVNVWEKVISFIENTSTPVDRHVSSSDRVGKPYRGVKPVFSIGDEEEYDTDEIDSSSMSDDDRKEVVNIQTWINKPDVKHHFPCKEVKESGHMFPSHLLVTATHMYCLREIVSRKGLAYIQSRQALNSVVKITSKKKHPELITFKYGNSSASGIEILAIERYLIPNAGDATKAIKQQIMKVLDALES
What is the function of this protein?
Putative Rab GTPase-activating protein which plays a role in vesicular trafficking.  Involved in endosome-to-Golgi trafficking.  Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles.  Together with WDR11 complex facilitates the golgin-mediated capture of vesicles generated using AP-1 (By similarity).  Plays a role in brain development, including in cortical neuron positioning (By similarity).  May also be important for neurite outgrowth, possibly through its involvement in membrane trafficking and cargo delivery, 2 processes that are essential for axonal and dendritic growth (By similarity).  May act as a general inhibitor of innate immunity signaling, strongly inhibiting multiple TLR and dectin/CLEC7A-signaling pathways.  Does not alter initial activation events, but instead affects maintenance of inflammatory gene expression several hours after bacterial lipopolysaccharide (LPS) challenge (By similarity).
What are the official names of this protein?
TBC1 domain family member 23.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle. Note=Localization to the trans-Golgi is regulated by ARL1 and ARL5B/ARL8. ARL1 increases Golgi localization, while ARL5B decreases it. Recruitment to the trans-Golgi network requires the presence of GOLGA1 and GOLGA4, but not that of FAM91A1. Recruited on AP-1-derived vesicles by WDR11 complex.
Protein: HELZ_DANRE
Sequence: MEDRRPQKSCDEAIGSLVRQEYEAAVAHSTEALLAMGPRTPTPSTALLRTRALLYRIAARLQLKDYDQADEDCKHVFAEELAKGDGSFRAGLQSLLLDGSLQEVCSVLSKALYGEPLNGIMTKDMTRLKRLLSEIEAARSKVVFSEENEEDVQEGWQFRPPPRGVTSSEEYTLCKRFLEQGLCRYGAQCTSAHSQEELTEWQRRYASRLIRLKQQQEGKHFSENYMEALIEKWINSLTPERVMNDCVDGVTVEHSSDLSITVNTKKSSHSWTFTLFCKPVRTLQRIALLYDANRPHFSIAAVSAGDASALEPQPVCPGGCQEWSAASPVQNGMDHCIYTVEIAFSTEIFGTFRQTVVFDLGCEPVLMQRVMVDAASIEDLEHLLQARQQLLMTAKRWDSSCKTIVEFVPNENMDLERSLLTRYQIPLSADQLFTQSVLDKTLTRDNYQPRLHDLLYIEEIAQYKEVTKFNIKVNLQLVTSFMLTGISGGAKYAQNGQLFARFKLTETLSEDTLAGRLVMTKVNSVLLLPVFKERMGQNQPAGAKERVYEALIEEKTKDYIFLRVCKECCDELGLVADQELQVELQFQLNRLPLCEMHYALDRVRDNSILFPDISLTPTIPWSPNRQWDEQLDPRLNAKQKEAILAITTPLSINLPPVLIIGPYGTGKTFTLAQAVKHILKQPESRVLICTHSNSAADLYIKDYLHPYVEAGNPHARPLRVYFRNRWVKTVHPLVQQYCLISGAHFTFQMPTRQDVERHRVVVVTLSTSQYLCQLDLEPGIFTHILLDEAAQAMECETIMPLALAVKSTRVVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPSEYPCRILLCENYRSHEAIINYTSDLFYEGKLMASGKQPPHKDFYPLTFFTARGEDVQEKNSTAYYNNAEVFEIVERVEEMRKKWPVSWGKLEEGSIGVVSPYADQVFRIRAELRKKRMSEVSVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTAIKRKEQLVEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSVGRCRKFWETFISICHENHSLHGITFEQIKIQLEALELKKTYVLNPLAPEFIPRALRSQHPPQQGPGKHQHSPPKAKGQLANHTEPFPPEGFVQPNAAVLMGNPIQAFTPPGAGAPASGKSPSPVQRLDPGASILYVPAVYGGNMVMPMPLPLPWAGYQSRFPMDPRIMSHQAAMYNLNLRPAASRTSPVLYGFSHASPLGLNQQQNTEKELLQEPSGNGKMDINGKAEHCRLLTPERKAPELKEKQGDLESVQNKSPEPQSNMGFPANRLIRKDPQRALNFHMAPPHPAFPSHHGTSQFPQQYGLSRPPLRMQTPMHPQASSFPPSFYSGPPMGPRGLQSPVLEGGEDPMGAGMSEDLKGVVRGLPAQMHQQPLRLNSFGEESLDSLLGDTLDGQASSGMDALQHQQQARVGQWGEHTPFLPAGVAPFPLPQQLAHLAQPGLRIPPQILRAGWGLGPAADEEPRPTMPRYPGLLREMLPQDQQYEQRDPAEMPPPQSRLLQYRQQIQPRSPGDLPSPSSSAPNHNFPAPAQPSYPDTSREPPVGFSQAPFPPDHSAGPLPVKYLLQEAHWPHPGHMLGHGLPFGLQAMAQRQDPGPLQHQQQKQQLQAPQSSLHSLDEYEPRGPGRPLYQRRISSSSPQPYPDSLEPQDQPVPSYRYPSADLWLGGPGPVPGPAPIHNIPCNGASHIGPHREILVSKAMSEEQMKAECLQPPPPPPPHPASAASLQHHGQFPPLLPSKQTPPDPGGGGNTSPAGHPKPPTMSYASALRAPPKPRPMLPEQSKKNSDPISLLQELSIGSSNSSNGYYTYFK
What is the function of this protein?
May act as a helicase.
What are the official names of this protein?
Probable helicase with zinc finger domain.
What is the protein family that this protein belongs to?
Belongs to the DNA2/NAM7 helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NAA11_HUMAN
Sequence: MNIRNAQPDDLMNMQHCNLLCLPENYQMKYYLYHGLSWPQLSYIAEDEDGKIVGYVLAKMEEEPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRPALHLYSNTLNFQISEVEPKYYADGEDAYAMKRDLSQMADELRRQMDLKKGGYVVLGSRENQETQGSTLSDSEEACQQKNPATEESGSDSKEPKESVESTNVQDSSESSDSTS
What is the function of this protein?
Displays alpha (N-terminal) acetyltransferase activity.  Proposed alternative catalytic subunit of the N-terminal acetyltransferase A (NatA) complex.
What are the official names of this protein?
N-alpha-acetyltransferase 11, N-terminal acetyltransferase complex ARD1 subunit homolog B, hARD2, NatA catalytic subunit Naa11.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ARD1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RECF_SALRD
Sequence: MILHTLRLRSFRAHAESEFDLAPSINLLYGANGAGKTNVLEAVHYLCLTKSFTASRDRYAVRKDAPYFEIEGRIGQVREEPMTVRLAYVPGEGKSIFVNGAELDRLADIVGTLPVVVFSPEDYDLTAGGPSERRRFVNNILSQARSVYMETLMKYRRARRQRNEVLRSYKKRSAPPPDELLAPWTEKLVGLGSRIVHRRQQFLQAFADDLEEAYRRIDAVAERPTIEYDTIADLAPDATPDAIEDEFRAALARKQGQERDRGTTLVGPQRDELVFRLDDLEVRRYGSQGQHRTFAMALKLAQYFYLQQRNDTEPLLLLDDAFGKLDAERTGVFLDLLRSDAVGQSLVTATRRGPFEPALNAEPASHRALQVRPGGGTAAVTPDPEYARGEATAANGAASAPTGADAASTSRD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOY_STAA2
Sequence: MAVFKVFYQHNRDEVIVRENTQSLYVEAQTEEQVRRYLKDRNFNIEFITKLEGAHLDYEKENSEHFNVEIAK
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: RK16_CAPBU
Sequence: MLSPKRTRFRKQHRGRLKGISSRGNRICFGRYALQTLEPAWITSRQIEAGRRAMTRNVRRGGKIWVRIFPDKPVTVRPAETRMGSGKGSPEYWVAVVKPGKILYEMGGVPENIARKAISIAASKMPIKTQFIISE
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HSP1_SMIAI
Sequence: MARYRRHSRSRSRSRYRRRRRRRSRHHNRRRTYRRSRRHSRRRRGRRRGYSRRRYSRRGRRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity).
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RLI1_YEAST
Sequence: MSDKNSRIAIVSADKCKPKKCRQECKRSCPVVKTGKLCIEVTPTSKIAFISEILCIGCGICVKKCPFDAIQIINLPTNLEAHVTHRYSANSFKLHRLPTPRPGQVLGLVGTNGIGKSTALKILAGKQKPNLGRFDDPPEWQEIIKYFRGSELQNYFTKMLEDDIKAIIKPQYVDNIPRAIKGPVQKVGELLKLRMEKSPEDVKRYIKILQLENVLKRDIEKLSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAAQIIRSLLAPTKYVICVEHDLSVLDYLSDFVCIIYGVPSVYGVVTLPASVREGINIFLDGHIPAENLRFRTEALQFRIADATEDLQNDSASRAFSYPSLKKTQGDFVLNVEEGEFSDSEILVMMGENGTGKTTLIKLLAGALKPDEGQDIPKLNVSMKPQKIAPKFPGTVRQLFFKKIRGQFLNPQFQTDVVKPLRIDDIIDQEVQHLSGGELQRVAIVLALGIPADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIVFEGIPSKNAHARAPESLLTGCNRFLKNLNVTFRRDPNSFRPRINKLDSQMDKEQKSSGNYFFLDNTGI
What is the function of this protein?
Component of the multifactor complex (MFC) involved in translation initiation.  Required for the binding of MFC to the 40S ribosome.  Required for the processing and nuclear export of the 60S and 40S ribosomal subunits.
What are the official names of this protein?
Translation initiation factor RLI1, ATP-binding cassette sub-family E member RLI1, RNase L inhibitor.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCE family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm.
Protein: TVA3_MOUSE
Sequence: MNMRPDTCSVLVLLLMLRRNNGDSVTQTEGLVTLTEGLPVMLNCTYQSTYSPFLFWYVQHLNEAPKLLFKSFTDNKRPEHQGFHATLHKSSSSFHLQKSSAQLSDSALYYCALSNAGAKLTFGGGTRLTVRP
What are the official names of this protein?
T-cell receptor alpha chain V region CTL-F3.
Protein: PNP_GEOSW
Sequence: MEQEKRIFSIDWAGRPLVVEIGQLAKQANGAVLVRYGDTVVLNTATASKEAKNVDFFPLTVNYEERLYAVGKIPGGFIKREGRPSEKAILASRLIDRPIRPLFAEGFRNEVQIVSMVMSVDQDCSPEMAALFGASLALTISDIPFEGPIAGVTVGRVDGEFVINPTVEQSEKSDIHLVVAGTKDAINMVEAGADEVPEEVILEAIMFGHEEVKRLIAFQEEIAAQVGKEKMEVVLYELDPQLEAEIRQLAEEDIKRAVQVPEKLARDAAIEEVKASVIAKYEEQEADEETLKQVNEILHKLVKEEVRRLITEEKIRPDGRKIDEIRPLSSEVGVLPRTHGSGLFTRGQTQVLSVCTLGALGDVQILDGLGIEETKRFMHHYNFPPFSVGETGPMRGPGRREIGHGALGERALEPVVPSEKEFPYTIRLVSEVLESNGSTSQASICASTLAMMDAGVPIKAPVAGIAMGLVKNDDNYTILTDIQGIEDHLGDMDFKVAGTAKGVTALQMDIKIKGLSREILEEALQQAKKGRMEILEHMMQTIREPRKELSKYAPKILTMQINPEKIREVIGPSGKQINKIIDETGVKIDIEQDGTIFISSVNEAMNQKAKQIIEDIVREVEVGQIYLGKVKRIEKFGAFVELFNGKDGLVHISELAEERVGRVEDVVSIGDEILVKVMEIDKQGRVNLSRKAVLRDKKEKKGKRPERHRMKP
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TF_MOUSE
Sequence: MAILVRPRLLAALAPTFLGCLLLQVIAGAGIPEKAFNLTWISTDFKTILEWQPKPTNYTYTVQISDRSRNWKNKCFSTTDTECDLTDEIVKDVTWAYEAKVLSVPRRNSVHGDGDQLVIHGEEPPFTNAPKFLPYRDTNLGQPVIQQFEQDGRKLNVVVKDSLTLVRKNGTFLTLRQVFGKDLGYIITYRKGSSTGKKTNITNTNEFSIDVEEGVSYCFFVQAMIFSRKTNQNSPGSSTVCTEQWKSFLGETLIIVGAVVLLATIFIILLSISLCKRRKNRAGQKGKNTPSRLA
What is the function of this protein?
Initiates blood coagulation by forming a complex with circulating factor VII or VIIa.  The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis.  TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
What are the official names of this protein?
Tissue factor, TF, Coagulation factor III.
What is the protein family that this protein belongs to?
Belongs to the tissue factor family.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein.
Protein: COA1_YEAST
Sequence: MMLRLVTKGLPKVTPSAAKAVLVRGSLLHSFSTSARFNNSVAEDEAKIVLKDKNRPLRIDRELPDPTTERRKRIAGFLLFSVAIGSALSLIFNYEKTESPIISNTLYYIRRSPATKNILGESIEFDGIIPWVYGELNSVKGRINITFYIKGDKNVTGTVRLVADRNTHDEEFLIHEWSVTAAGQKIDLLAENTKTPI
What is the function of this protein?
Required for efficient assembly of cytochrome c oxidase in the mitochondrial inner membrane.  Involved in a step coupling MSS51-dependent cotranslational insertion of COX1 to the addition of its heme A and copper B cofactors.
What are the official names of this protein?
Cytochrome c oxidase assembly factor 1.
What is the protein family that this protein belongs to?
Belongs to the COA1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.