PharMolix/UniProtQA huggingface dataset:
Protein: DDL_CLOB8
Sequence: MKIGVIMGGISSEREISLQSGKSIIENINKEKYEVLPIVIDKKEDIINKSKGIDFALLALHGQFGEDGTVQSVLQTLGIPYSGCGPLSSAMCMDKDVSKSVLEANGIRTAPWINLRKGDNIDFNKINELGYPVVVKPTHGGSSVATFIVKEEKEIENCVSEAFKWDSEVMIEKFIKGDEITCPVYNNKMLPVIAIKPKAEFFDFTSKYQDGGAEEIVVELEAELHKEVEKMALETYKALKCEVYSRVDMIVTEEGVPYILEINTLPGMTKNSLIPKSAAALNIGFSELIDMIIQDSLKISR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_PYRAB
Sequence: MAYKEYRDKVLHFIEEHEKWRSHTINLIASENITSPSVNRAVASGFMHKYAEGWPRQRYYQGCKYVDEVELIGVELFTKLFKSDYADLRPISGTNANQAVFFGLGQPGDKVIVLHTSHGGHISHMPFGAAGMRGLEVHTWPFDNESFNIDVDKAEKMIRELEPKIVVFGGSLFPFPHPVKELAPVAKEVGAFVVYDAAHVLGLIAGGEFQDPLREGADIMTASTHKTFPGPQGGVILYKKFADDETIAKLQWAIFPGVLSNHHLHHMAGKVITAAEMLEYGEAYAKQIVKNAKALAEALAEEGFKVIGEDQGYTKSHQVIVDVSDLHPAGGGWAAPLLEEAGIILNKNLLPWDPLEKVNEPSGLRIGVQEMTRVGMMEDEMKEIAHFMKRVLLDKEDPKKVRKDVYYFRLEYQKVYYSFDYGLPMKE
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier.  Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENDA_SULIN
Sequence: MVKALLVGSKVLIPNVDESRYIYSNGFYGKAVGISKPKDPKDIIRPLELSLIESVYLAKKGLIKVIDKNGEVLEYEKLYEYSSKIINKFDIMYRVYEDLREKGFIVRSGVKYGADFAVYTLGPGLEHAPYVVIAVDIDEEITPHELLSFGRVSHSTRKRLVLALVDRKSESVRYIMFKWVKM
What is the function of this protein?
Endonuclease that removes tRNA introns.  Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron.  The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini.  Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
What are the official names of this protein?
tRNA-splicing endonuclease, tRNA-intron endonuclease.
What is the protein family that this protein belongs to?
Belongs to the tRNA-intron endonuclease family. Archaeal short subfamily.
Protein: RRP12_YEAST
Sequence: MDQDKVAFLLELEDKLAKIRSQVNSKLENQKHIAIILTAVEENIAGQATNDVSKNIVNYIISFMSLLDQAVDPSTHEIKDIQLASSSTYLLDLIFHYSPKVLLRSKFSEILTKIAPCITAEKANAPLIRAAIGCLESLLIAQDAQAWNNTYDLNVTPKRGLQGILELSLDVRPKVRKRALDAVHAVLLNPPVAPTAEHVAAVFVADFCDKQLAGILNDLSNLSNKQLKAQKTKEDINASVMRSLRLITSVVSTGQWPSSQIEPLCDVLLGVTKSSEQYLVSASFECFESMFKTMAETTISSGLAENKYLRVLDTIFALKPSNVDTLLTKSWIAVVIKGMSTYATHQPLKALRKIPGVFHIMCTYLASETPEVYQAASQCLISILSESVKDDLLLYTPSVDEKVFKNVDEIISQIAKTFIDFLSIRYSHCSREILKILVAAFNKFRYRSNPHFLKSLKIVDTWRVNEEQFMDLRNEIELVIGASISAMGPEMILAEAPLNLDNPSSERPGRAWLLPLIRDYTKNANLATFQNELAPYIKSFQSKFDKVPEESIQLRVFQTIVDQIWSTLPRFCELPMDLRESFTDEFASELSSLLYSEVELRTTICHALKVLAESNVSYAEESSSHNVLLLQRFPISEAQKNIEYLSTKSTNLLAVLFNVYTQTTPNARSYILETIDQYLKITSKEDLEKTFNNVCGLLKNSMNEESSGNVNKEKKKPQLTATLLDLIICMITYLPVSSYSALFSMFSLTVNSADALIQKRAYRIITKLSELKSGSTAVAQFISDIENVMVDSASSVQTSAKAARLTAIKTIVELLPLDHLDFIVRTVAEVILSTKDVNEKSRETAFDTLICMGRKMNEPNGIIKLFQIPGYDPTTPDQSSSISEFFKIISAGLIGESQHMVSSSITGYACLVFEFKNELDSGILMDIYDTIELYLTSNSREIVKSAIGFTKVCVLGLPEELMRPKVPELLLKLLRWSHEHTGHFKAKVKHIIERLIRRFGYDYIEANFPEEDRRLLTNIRKMRNRNKRKDEEVTTGVSDVAATKGSRFMSAFDEAVYGSDEENDNGSDQEENVAGGKMKNGAKQFIVESGDNPLDLLDSQTLAHISSTRPKKFNKNQNRARFNDDAFNFDSEGKLVVKGQPKPSTNVDDPLSAVTSGINAYLEAVKSGPVRGQRNKLKFRKNGKDSDEFGDDDDGEKDSRLMRGRVNQGNKIGKHNKKGPKFKSRKKL
What is the function of this protein?
In association with GSP1, required for nuclear export of both pre-40S and pre-60S ribosomal subunits.  Required for the late maturation of the 18S and 5. 8S rRNA of the pre-40S ribosomes and for maturation of the 25S and 5. 8S rRNA of the pre-60S ribosomes.
What are the official names of this protein?
Ribosomal RNA-processing protein 12.
What is the protein family that this protein belongs to?
Belongs to the RRP12 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: NLR9B_MOUSE
Sequence: MAGSSGYGLLKLLQKLSDEEFQRFKELLREEPEKFKLKPISWTKIENSSKESLVTLLNTHYPGQAWNMMLSLFLQVNREDLSIMAQKKKRHKQTKYKKFMKTTFERIWTLETNTHIPDRNYHLIVEVQYKALQEIFDSESEPVTAIVAGTTGEGKTTFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSTLPESSETVDDILSDPKRILFILDGFDYLKFDLELRTNLCNDWRKRLPTQIVLSSLLQKIMLPGCSLLLELGQISVPKIRHLLKYPRVITMQGFSERSVEFYCMSFFDNQRGIEVAENLRNNEVLHLCSNPYLCWMFCSCLKWQFDREEEGYFKAKTDAAFFTNFMVSAFKSTYAHSPSKQNRARLKTLCTLAVEGMWKELFVFDSEDLRRNGISESDKAVWLKMQFLQTHGNHTVFYHPTLQSYFAAMFYFLKQDKDICVPVIGSIPQLLGNMYARGQTQWLQLGTFLFGLINEQVAALLQPCFGFIQPIYVRQEIICYFKCLGQQECNEKLERSQTLFSCLRDSQEERFVRQVVDLLEEITVDISSSDVLSVTAYALQKSSKLKKLHLHIQKTVFSEIYCPDHCKTRTSIGKRRNTAEYWKTLCGIFCNLYVLDLDSCQFNKRAIQDLCNSMSPTPTVPLTAFKLQSLSCSFMADFGDGSLFHTLLQLPHLKYLNLYGTYLSMDVTEKLCAALRCSACRVEELLLGKCGISSKACGIIAISLINSKVKHLSLVENPLKNKGVMSLCEMLKDPSCVLQSLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDTGVNLLCEALKDPNCTLKELWLPGCFLTSQCCEEISAVLICNRNLKTLKLGNNNIQDTGVRQLCEALSHPNCNLECLGLDLCEFTSDCCKDLALALTTCKTLNSLNLDWKTLDHSGLVVLCEALNHKRCNLKMLGLDKSAFSEESQTLLQDVEKKNNNLNILHHPWFEAERNKRGTRLVWNSRN
What is the function of this protein?
As the sensor component of the NLRP9 inflammasome, plays a crucial role in innate immunity and inflammation.  In response to pathogens, including rotavirus, initiates the formation of the inflammasome polymeric complex, made of NLRP9, PYCARD and CASP1.  Recruitment of proCASP1 to the inflammasome promotes its activation and CASP1-catalyzed IL1B and IL18 maturation and release in the extracellular milieu.  The active cytokines stimulate inflammatory responses.  Inflammasomes can also induce pyroptosis, an inflammatory form of programmed cell death.  NLRP9 inflammasome activation may be initiated by DHX9 interaction with viral double-stranded RNA (dsRNA), preferentially to short dsRNA segments.
What are the official names of this protein?
NACHT, LRR and PYD domains-containing protein 9B, NALP-delta.
What are the subcellular locations of this protein?
Cytoplasm. Inflammasome.
Protein: VATL_DICDI
Sequence: MFQLLSFLLSGEATAVERIITDACPVYAPFFGAMGVTAALVFTVMGAAYGTAKASVGISNMGVMKPDLVIKAFIPVIFAGVIAIYGLIICVILVGGIKPNANYTLMKSFTDLGAGLTVGLCGLAAGMAIGIVGDSGVRAFGQQPKLYVIMMLILIFSEALGLYGLIIGILLSSVSDTYCPGQALVPLNSGNVIGKN
What is the function of this protein?
Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase.  V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
What are the official names of this protein?
V-type proton ATPase proteolipid subunit, V-ATPase 16 kDa proteolipid subunit, Vacuolar proton pump 16 kDa proteolipid subunit.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase proteolipid subunit family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: H2B11_XENLA
Sequence: MPEPAKSAPAPKKGSKKAVTKTQKKDGKKRRKSRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B 1.1, H2B1.1.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: UGPB_ECO57
Sequence: MKPLHYTASALALGLALMGNAQAVTTIPFWHSMEGELGKEVDSLAQRFNAENPDYKIVPTYKGNYEQNLSAGIAAFRTGNAPAILQVYEVGTATMMASKAIKPVYDVFKEAGIQFDESQFVPTVSGYYSDSKTGHLLSQPFNSSTPVLYYNKDAFKKAGLDPEQPPKTWQDLADYAAKLKASGMKCGYASGWQGWIQLENFSAWNGLPFASKNNGFDGTDAVLEFNKPEQVKHIAMLEEMNKKGDFSYVGRKDESTEKFYNGDCAMTTASSGSLANIREYAKFNYGVGMMPYDADAKDAPQNAIIGGASLWVMQGKDKETYTGVAKFLDFLAKPENAAEWHQKTGYLPITKAAYDLTREQGFYEKNPGADTATRQMLNKPPLPFTKGLRLGNMPQIRVIVDEELESVWTGKKTPQQALDTAVERGNQLLRRFEKSTKS
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Binds G3P.
What are the official names of this protein?
sn-glycerol-3-phosphate-binding periplasmic protein UgpB.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SCLT1_MOUSE
Sequence: MATEIDLLRDQKDKLNDILRQHQIEHIFRDPTMQNSMSKGGRGDTLVDSINEQSSLPPLIAEYEKHLEELNRQLTYYQKHMGEMKLQLETVITENERLHSKLKDAVEKQLEALPFGTGIGNDICADDETVRILQEQLQLANQEKTWALELWQTASQELQSVQKLYQEHMTEAQIHEFENRKQKDQLNNFQQLTKKLHVANENIEMTNHHFLKTVTEQNMEIEKLRKHLRQARLDLRVAVSKVEELTKVTEGLQEQMLKKEEDIMSAQGKEEASDRRVQQLQSSIKQLESRLCVAIEEADVLKTGKSNLEKQIKELQAKCSESENEKYEAISRARDSMQLLEEANIKQNQILLEEKQKEVDREKMKKTMSQLIQDAAIKARKEVESTKKQYEILISQLKEELSTLQMDCDEKQGQIDRAIRGKRAVEEELEKIYREGKQDESDYRKLEEMHQRCLAAERSKDDLQLRLKSAENRIKQLEINSSEEMSRSHEMIQKLQTVLESERENCGFVSEQRLKLQQENEQLQKETEDLRKVALEAQKKAKLKVSTMEHQFSIKEHGFEVQLREMEDSNRNSIVELRHLLAAQQKTANRWKEETKKLTESAEMRISSLKSELSRQKLHTQELLSQLEMANEKVAENEKLILEHQEKANRLQRRLSQAEERAASASQQLSVITVQRRKAASMMNLENI
What is the function of this protein?
Adapter protein that links SCN10A to clathrin.  Regulates SCN10A channel activity, possibly by promoting channel internalization (By similarity).
What are the official names of this protein?
Sodium channel and clathrin linker 1, Sodium channel-associated protein 1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane.
Protein: RL24_OCEIH
Sequence: MHVKKGDKVKVLSGKDRGKEGTVLEAFPKNERVLVEGVNMVQKHAKPSQENPQGGILNIEAPIHVSNVLPVDPKSGEPTRVGYEVKDGKKIRIAKKSGEALDK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RECU_STRGC
Sequence: MVNYPHKLTSKNNIKKVKKETVDFANRGMTFEKMINDTNDYYLSRGLAVIHKKPTPVQIVKVDYPKRSRAKIVEAYFRQASTTDYSGVYRGHYIDFEAKETRQKQSMPMKNFHAHQIEHMNQVLNQGGICFVLLHFSSLKETYLLPAPYLIEFYKIDKGGKSMPLDYIQKHGYLIEQNILPSVPYLDIISKNLLGGHSNE
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_MYCBO
Sequence: MLRARNRMRRSADFETTVKHGMRTVRSDMVVYWWRGSGGGPRVGLIIAKSVGSAVERHRVARRLRHVAGSIVKELHPSDHVVIRALPSSRHVSSARLEQQLRCGLRRAVELAGSDR
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: ZORB_ECOLC
Sequence: MDKIIGKQLPKKDQDNEHWVSMSDLMAGLMMVFMFISIAYMHYVRIEKEKIKEVAVAYENAQLQIYNALDIEFAKDLQDWDAEIDKQTLEVRFKSPDVLFGLGSTELKPKFKLILDDFFPRYLKVLDNYQEHITEVRIEGHTSTDWTGTTNPDIAYFNNMALSQGRTRAVLQYVYDIKNIATHQQWVKSKFAAVGYSSAHPILDKTGKEDPNRSRRVTFKVVTNAELQIRKIIQE
What is the function of this protein?
Component of antiviral defense system Zorya type II, composed of ZorA, ZorB and ZorE.  Expression of Zorya type II in E. coli (strain MG1655) confers resistance to phages SECphi7 and T7.  While most T7 infected Zorya-containing cells undergo abortive infection, a minority produce viable phage progeny.  These eventually accumulate to a high multiplicity of infection, leading to culture collapse by 170 minutes after initial infection (PubMed:29371424).  ZorA and ZorB probably assemble in the cell inner membrane and exert their effect there (Probable).
What are the official names of this protein?
Zorya protein ZorB.
What is the protein family that this protein belongs to?
Belongs to the MotB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RECC_BUCAI
Sequence: MFTIYKSNSLNTLLLKAYHIIEEKPFSNIFEKEIFIYDNKVLFQYLNIFIAEKKGISANFKFYHPNDFIWKLFKIILSKKELKNIFTHSMIIWEIIKILDNKKFFENCSKKKDMIKKFKFSFLMASIFKKYILYRPEWINQWEIEKNISIFDKNEQWQIKLWMEIIHNTKKINQSSDHFANLFYNIQKIIKEKKIKKKYLPKRFFIISSFSMNPSYIKIFQNISIYTDIYFLYITPFKKNIFNFIQDNKIFTDIKIEKKNILNDSLITLWGQYEEIYYFYILKSKKNKVINCFKKNKNKSLLSQIKNNFFNDSEFTRKKRFLEISDHSISINICFNKKNEIEVLYEKLLIFLNENSSIKPGDIVVTSFSLDTYISSINLIFQSIDNKKTIPFFIAKKSSKTTEIMLWSFKKILNLSNSRFENEEILELLDVPEIAEKFNFSEEEIKILYHWIEETNIRWGINEKHKNYLLFPKNKQNTWFYGIEKLLLSYAMNDTEKIWNGVLSCSFINGSRSELIGKLISFIKILEKWQKKLSKLQYLTYWRSLYSDLVSDFFQNNTKIEKSIQIIQKKWIEIIDDSLSSNYLKKISINILKKIFFYKYYDNNHEIFLPGVVNFCYPDSVCYIPFKVICMIGTDHTSIPKTNYLDNFNLLKKYPLIGDINLYQKYSYLFVQSLSCAEKYFYISYIGYSVKDESKVHPSILVDQLLNYITLNFCFIGDQNLSYKENSKKITKYLCKKHKKQFFYETKNIESFIQDDIKNDFKHTEKNISHKNLLKKNTDNEINLKDLINFWKHPIRYFYNSHLKIKIRQKKQKINTTETFLVNPLNSFKIKNKLLDYIIHNKNITKLYQHYLLSGKLPYHFFGEIFWIKNIKEMKLIANKVMQYRIEKEEKKINLNIEKYQIYGVLSEIQSTGLLRWKTSSIRYSDRIALWLEHLIYSILGGCGKSKIIGYKSQIWSFSSLNSHRAHSYLLEYIKGYIKGMKEPLFLTKSGASWLDQVYDERNNCIKNDYYTKIKAYKKLLYTWKGDNYTEGEQEDYYLKKTITISNKKNIKKICESAEKWLIPILKNKG
What is the function of this protein?
A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair.  Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity.  Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction.  Cuts ssDNA a few nucleotides 3' to the Chi site.  The properties and activities of the enzyme are changed at Chi.  The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair.  Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination.  In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
What are the official names of this protein?
RecBCD enzyme subunit RecC, Exonuclease V subunit RecC, ExoV subunit RecC, Helicase/nuclease RecBCD subunit RecC.
What is the protein family that this protein belongs to?
Belongs to the RecC family.
Protein: XPR1_CRIGR
Sequence: MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKELAKINTFYSEKLAEAQRRFATLQNELQSSLDAQRESIGVTTLRQRRKPVFHLSHEERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKILKKHDKILETSRGADWRVGHVEVAPFYTCKKINQLISETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLFCGIFIVLNITLVLAAVFKLETDRTVWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHVLIFELNPRNNLSHQHLFEIAGFLGILWCLSLLACFFAPISVVPIYVYPLALYGFMVFFLINPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQLNSLSVILMDLEYMICFYSFELKWDENKSLLPNDLQEPEFCHRYTYGVRAIVQCIPAWLRFIQCLRRYRDTKRAFPHLVNAGKYSTTFFTVTFAALYSTHKERQHSDTMVFLYLWVVFCAISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYPQKAYYYCAIIEDVILRFAWTIQISITATAFQPHVGDIIATVFAPLEVFRRFVWNFFRLENEHLNNCGEFRAVRDISVAPLNADDQTLLEQMMDQEDGVRNRQKNRSWKYNQSISLRRPRLASQSKARDTKVLIEDTDDEANT
What is the function of this protein?
Plays a role in phosphate homeostasis.  Mediates phosphate export from the cell.  Binds inositol hexakisphosphate (Ins6P) and similar inositol polyphosphates, such as 5-diphospho-inositol pentakisphosphate (5-InsP7); these are important intracellular signaling molecules.
What are the official names of this protein?
Xenotropic and polytropic retrovirus receptor 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SYG1 (TC 2.A.94) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DNAA_LACLS
Sequence: MASLNENQKFWARVTELARQSIGKQAYDFFIEPAQLMSVEQDTANILLDSGMKKDYWKKQSDLITTAGFEVFGRMIDYELYANDELTDIELRRLNNQSPVDEPLSVAKPTSPLVSGLNEKYNFENFVQGPGNRWTLAAAIAVADKPGDTYNPLFIYGGAGLGKTHLMHAIGNQILTDNPTARIKYVSSENFVNDYVNATRKNQMESFENTYRNLDLLLLDDVQFFSDKEGTKNEFFNTFNALYDKGSQIVLTSDRIPQELNNLEDRLVSRFSWGLTTDITAPDYETRMAILLIKSESSHLEFPSETLSYIAGQIDSNVRELEGALNRVEFVARANGISIVDIETASQALRSLKNATQQSLSNLTIKKIQDEVANYYHISFSDLVGPKRPKEIAFPRQIAMYLVRELLGTSLPAIGTAFGGRDHTTVMYAYKQISDKMKNDMDVQKDIDSIKRKF
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_STRGR
Sequence: MYAIVRSGGRQHKVAVGDIVEVDKISTAKVGDTVELSTLLVVDGDAVTSDPWVLDGIKVTAEIVDHHKGAKIDILRYKNKTGYRRRQGHRQQYTAIKVTGIPAAAK
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: DQX1_BOVIN
Sequence: MASQLLGLEEESGPNPEESELAVNPFDGLPFSSRYYKLLEQRRSLPVWAARFIFLEHLESSPSGVVLVSGEPGCGKSTQIPQWCAEFVLARGFQKGWVTVTQPYPLAALSLALRVADEMDLTLGHEVGYSIPQEDCTGPDTLLRFCWDRLLLQEVASTRGTGARGVLILDEAQERSVASDLLQGLLRDARLGSLPGDLRVVVVTDPSLEPKLQDFWGGPPTVCVPRKTGSCPTPVYRDSLPADRVDAACQAVLEWCQEEAPGDVLVYLPSEEEISLCCESLSRKVRSLENQGPPPRVLPLHPGCGQAVQAVYEDTESGARKVVVTHWLADFSFSLPSIRHVIDSGLELRSVYSPQIRAESQVLRPVSKCQAEARRLRAAGIPPGSCLCLYPKSFLELEAPYLPQPRVWAENLSSLMLLLKRRQIAEPGKCHFLDRPAPEALMQALEDLDYLAALDDDGDLSDLGVILSEFPLAPELAKALLASCEFDCVDEMLTLAAMLTAAPGFTRPPVCAEEAALRRALEHVDGDHSSLIQVYEAFIQSGADKAWCQARGLNWAALCQARKLRGELLELMQRIELPLSQPAFGSERNRRDLQKALVSGYFLKVARDTDGTGNYLLLTHKHVAQLSPNCCYRSRRAPARPPLWVLYHSFSISKDNCLSIVSEIQPQMLVELAPPYFLSNLPPSESRDFLNQLREERTDSSIRSESSSTQELENACALQ
What are the official names of this protein?
ATP-dependent RNA helicase DQX1, DEAQ box polypeptide 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: YIDD_CHLAB
Sequence: MSFKQLLYNLPTHLCCGLIHLYRWTISPLLGSPCRFFPSCSQYALQALKHHKCIRGLWLTIKRIGKCGPWHPGGIDLVPMTTLEEALDVSQVTNDDDSGDSHA
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ATPG_RIPO1
Sequence: MPNLKAIRDRIQSVKNTKKITEAMRLVAAAKVRRAQEQVIATRPFADALANVLYNLLNRLQYGDVSLPLLQQRQVKTVALVVVSGDRGLCGGYNTYVIRRAEQRQKELEAQGINYRLITIGRKATQYFSRRQAPIEKTYVGLNQIPTADEAGSIADELLSLFLSETVDRVELIYTRFVSLISSRPVVQTLLPLTVQGLEVEDDEVFRLITRDGKLRVERETIAQEVSSFPQDMIFEQDPIQILDALLPLYINNQLLRGLQEAAASELAARMTAMSNASDNAGQLIGTLTLSYNKARQAAITQQLMEVVAGANAL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: Y2645_MYCTO
Sequence: MTTTPRQPLFCAHADTNGDPGRCACGQQLADVGPATPPPPWCEPGTEPIWEQLTERYGGVTICQWTRYFPAGDPVAADVWIAADDRVVDGRVLRTQPAIHYTEPPVLGIGPAAARRLAAELLNAADTLDDGRRQLDDLGEHRR
What are the official names of this protein?
Uncharacterized protein MT2723.
Protein: RS11_ALKEH
Sequence: MAKAATRSRTKRAKRTVVDGIAHINATFNNTIITITDRQGNGLAWASAGGSGFRGSRKSTPFAAQVASERAGRAALDYGLKNLEVRVKGPGPGRESAVRALNAVGYRITNISDVSPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: CHED_BACVZ
Sequence: MSRAEAAVVKVGIADVQVARYPDKIRTSGLGSCVGLVLYDKDKQTAGLVHVMLPDSGLSKTAELNRAKYADTAVKMTIDMLLKAGCRKFALKAKLAGGAEMFKFKMTNDLMKIGPRNVAAIKEQLSLYNIPVISEDTGGSSGRTIEFEPKSCMLHIRTVKQGETTI
What is the function of this protein?
Deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs).  CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase (By similarity).
What are the official names of this protein?
Chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: ENGB_BACC0
Sequence: MKVTKADIVISAVKPEQYPDGDLPEIALAGRSNVGKSSFINKILNRKKLVRISSKPGKTQTLNFFLINEMMHFVDVPGYGYAKVSKTERAAWGKMIETYFTTREQLDAAVLVVDLRHKPTNDDVMMYDFLKHYDIPTIIIATKADKIPKGKWQKHLKVVKETLDIESGDEVVLFSSETGLGKEEAWKAIHKFTKTKNA
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: SBP2L_HUMAN
Sequence: MDRAPTEQNVKLSAEVEPFIPQKKSPDTFMIPMALPNDNGSVSGVEPTPIPSYLITCYPFVQENQSNRQFPLYNNDIRWQQPNPNPTGPYFAYPIISAQPPVSTEYTYYQLMPAPCAQVMGFYHPFPTPYSNTFQAANTVNAITTECTERPSQLGQVFPLSSHRSRNSNRGSVVPKQQLLQQHIKSKRPLVKNVATQKETNAAGPDSRSKIVLLVDASQQTDFPSDIANKSLSETTATMLWKSKGRRRRASHPTAESSSEQGASEADIDSDSGYCSPKHSNNQPAAGALRNPDSGTMNHVESSMCAGGVNWSNVTCQATQKKPWMEKNQTFSRGGRQTEQRNNSQVGFRCRGHSTSSERRQNLQKRPDNKHLSSSQSHRSDPNSESLYFEDEDGFQELNENGNAKDENIQQKLSSKVLDDLPENSPINIVQTPIPITTSVPKRAKSQKKKALAAALATAQEYSEISMEQKKLQEALSKAAGKKNKTPVQLDLGDMLAALEKQQQAMKARQITNTRPLSYTVVTAASFHTKDSTNRKPLTKSQPCLTSFNSVDIASSKAKKGKEKEIAKLKRPTALKKVILKEREEKKGRLTVDHNLLGSEEPTEMHLDFIDDLPQEIVSQEDTGLSMPSDTSLSPASQNSPYCMTPVSQGSPASSGIGSPMASSTITKIHSKRFREYCNQVLCKEIDECVTLLLQELVSFQERIYQKDPVRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSKGGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYFGAESLFNKLVELTEEARKAYKDMVAAMEQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEYETNWRNMVETSDGLEASENEKEVSCKHSTSEKPSKLPFDTPPIGKQPSLVATGSTTSATSAGKSTASDKEEVKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNVEQSGEEEAEAPEVLEPGMDSEAWTADQQASPGQQKSSNCSSLNKEHSDSNYTTQTT
What is the function of this protein?
Binds SECIS (Sec insertion sequence) elements present on selenocysteine (Sec) protein mRNAs, but does not promote Sec incorporation into selenoproteins in vitro.
What are the official names of this protein?
Selenocysteine insertion sequence-binding protein 2-like, SECIS-binding protein 2-like.