PharMolix/UniProtQA huggingface dataset:
Protein: LATA_LATHE
Sequence: MIFVGETMERANHSLVRLRREGEELTLDEKAEICSELELQQKYVDIASNIIGDLSSLPMVGKIVGTIAAAAMTVTHVASGRLDIEQTLLGCSDLPFDQIKEVLEKRFNEVDRKLESHSAALEEITKLVEKSISAVEKTRKQMNKRFDEVMKSIQDAKVSPIVSKINNFARYFDTEKERIRGLKLNDYILKLEEPNGILLHFKESRTPKDDSLQAPLFSIIQEGYAVPKSIDDESAFKVLYALLYGTQTYISVMFFLLEQYSFLANHYYEKGDLEKYDEYFNSLNNVFLDFKSSLVGTGTSNNEGLIDKVLQVLMTFKNSEFLGLGKNGVDEMLNEKINLFNKIKEEIESKQRMTMSETPENFAQISFDKDITTPIGDWRDGREVRYAVQYASETLFSKIGHWSDPVSVREKACPTLRMPVDQTRRNVLVFRKFDNSKPQLVGEITPYLSNFIDIDRDLYNAASNPDSAVGFKEFTKLNYDGANIRATFDQGRTIFHAVAKSGNDKILFGLTFLVKSTELNQPDKKGYTPIHVAADSGNAGIVNLLIQRGVSINSKTYHFLQTPLHLAAQRGFVNTFQRLMESSEININERDKDGFTPLHYAVRGGERILEAFMNQIGIDVNAKSNKGLTPFHLAIIKNDWQVASTLLRNKKVDINAVDENNMTALHYAAILGYLETTKQLINLKEINANVVSSPGLLSALHYAILYKHDDVASFLLRSSNVNVNLKALGGITPLHLAVMQGRKQVLSLMFNIGVNIEQQTDEKYTPLHLAAMSKYPELIQILLDQDSNFEAKTNSGATPLHLATFKGKSQAALILLNNEVNWRDTDENGQMPIHGAATTGLLDVAQAIISIDATVLDIEDKNSDTPLNLAAQNSHIDAVKYFIDQGADINTRNKNGHAPLLAFSKKGNLDMVKYLFDKNANVYIADNNGMNFFYYAVRNGHLNIIKYAMSEKDKFEWSNIDNNRRDECPKEECAISHFAVCDAVQFDKIEIVKFFIGTLGNFNICGPLHQAARYGHLHIVKYLVEEEVLSVDGSKTDTPLCYASENGHLAVVQYLVSNGAKVNHDCANGMTAIDKAITKNHLQVVQFLAANGVDFRRKNSRGATPFLTAVAENAFDIAEYLIREKRQDININEQNVDKETALHLAVYYKNLQMIKLLVKYGIDVTIRNAYDKTVLDIATDAKFSNIVKYLKKNSGKFRREYKSSYGEHSFLQTNEISRFIDGKSIEHDHPQFINADNESSQLFSGTASKIDVIGTLLLIDVLIRYFSKQGYISKESDSASDGITQAAALSITEKFEDVLNSLPNKSAKEQVDLADVHGKVYAALKSGRNSQIHQILCSSLKSISTLKPEDMEKLVSVIMNSHSSLSMPEATDSANEAYGETLHLFGESCRHSEDYISQKFSTNPFSFESEKKIQKISI
What is the function of this protein?
Presynaptic neurotoxin that causes massive release of neurotransmitters from vertebrate (but not invertebrate) nerve terminals and endocrine cells via a complex mechanism involving activation of receptor(s) and toxin insertion into the plasma membrane with subsequent pore formation.  Binds to neurexin-1-alpha (NRXN1) in a calcium dependent manner, adhesion G protein-coupled receptor L1 (ADGRL1, also termed latrophilin-1 and calcium-independent receptor of latrotoxin (CIRL)), and receptor-type tyrosine-protein phosphatase S (PTPRS), also termed PTP sigma.  NRXN1 and PTPRS are suggested to provide a platform for binding and subsequent pore formation events.  In contrast, binding to ADGRL1 does not involve oligomerization and channel formation, but direct downstream stimulation of the synaptic fusion machinery.
What are the official names of this protein?
Alpha-latrotoxin-Lhe1a, Alpha-LTX-Lhe1a, Alpha-latrotoxin, Alpha-LTX.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 01 (latrotoxin) family. 03 (alpha-latrotoxin) subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a membrane channel in the prey.
Protein: HRCA_STRA5
Sequence: MITQRQNDILNLIVELFTQTHEPVGSKALQRTIDSSSATIRNDMAKLEKLGLLEKAHTSSGRMPSPAGFKYFVEHSLRLDSIDEQDIYHVIKAFDFEAFKLEDMLQKASHILSEMTGYTSVILDVEPARQRLTGFDVVQLSNHDALAVMTLDESKPVTVQFAIPRNFLTRDLIAFKAIVEERLLDGSVMDIHYKLRTEIPQIVQKYFVTTDNVLQLFDYVFSELFLETVFVAGKVNSLTYSDLSTYQFLDNEQQVAISLRQSLKEGEMASVQVADSQEAALADVSVLTHKFLIPYRGFGLLSLIGPIDMDYRRSVSLVNIIGKVLAAKLGDYYRYLNSNHYEVH
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: CREA_ASPCL
Sequence: MPPSASSVGFSDLLNPQNPTESAPSTPVNKSPASSAPSSAQSNSTMASSVSLLPPLMKGTRPANEEPRQDLPRPYKCPLCDRAFHRLEHQTRHIRTHTGEKPHACQFPGCTKRFSRSDELTRHSRIHNNPNSRRNNKAQHLAAAAAAAANQDNVLVNNTGSMMPPPSKPITRSAPVSQVGSPDISPPHSFTNYAGHMRSNLGPYARNNERASSGMDINLLATAASQVERDEHFGFHNGPRGLPLFSSRLHNSSRLPSLSAYAISQNMTRSHSHDEEDVYSHRVKRSRPNSPNSTAPSSPTFSHDSLSPTPDHTPLATPAHSPRLRPLGTSELQLPSIRHLSLHHTPALAPMEPQPEGPNYYSPTQPHHGPSISDIMSKPDGTQRKLPVPQVPKVAVQDMLNPTGFVSVSSSTSNSVAGGDLAERF
What is the function of this protein?
Transcription regulator component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB.  Represses the transcription of the alcR, alcA and aldA genes by binding to a GC-rich region in their promoter.  Also plays a role in response to carbon starvation and the control of extracellular proteases activity (By similarity).
What are the official names of this protein?
Probable DNA-binding protein creA, Carbon catabolite repressor A.
What is the protein family that this protein belongs to?
Belongs to the creA/MIG C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS2_PSEAE
Sequence: MSDTLTRLAAVLEERKNAAPDSSYVASLYHKGLNKILEKVGEESVETIIAAKDAAASGDCQDLIYETADLWFHSLVMLSALGQHPQAVLDELERRFGLSGHAEKAARQPSA
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RD521_ARATH
Sequence: MAGLGLRLKAAKWTLRSGSGAVSREWSSEMGKGVRRFSTETENDVPTSGISRPLAEILKELNKKVPDSVIRTRVEDGCSIKYIPWHIVNRIMNMHAPEWSGEVRSVTYSPDGNTVTVAYRVTLYGTDAEIFRESTGTTSVDDKGYGDAVQKAEAMAFRRACARFGLGLHLYHEDAL
What is the function of this protein?
Plant-specific single-stranded DNA-binding protein required for efficient heterologous recombination-dependent DNA repair in nuclear and mitochondrial compartments.  Forms large nucleo-protein complexes with WHY2 in mitochondria.  Binds ssDNA with high affinity, but with little sequence specificity (PubMed:22762281).  Involved in double-stranded DNA break repair (PubMed:22202891).  Involved in the hydrolytic splicing pathway in mitochondrion.  Facilitates the excision of two cis-spliced group II introns, NAD1 intron 2 and NAD2 intron 1 (PubMed:26048959).
What are the official names of this protein?
DNA repair RAD52-like protein 1, mitochondrial, Organellar DNA-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the RAD52 family.
What are the subcellular locations of this protein?
Mitochondrion. Nucleus.
Protein: SYL_NEIM0
Sequence: MQEQYRPAAIEPAAQKKWDDARIFNVSEDASKPKYYCLSMFPYPSGKLHMGHVRNYTIGDVLSRFKRLNGFNVMQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIEYMKTQLKSLGFAIDWARETATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDPVDQTVLANEQVIDGRGWRSGALIEKREIPMYYFKITDYAEELLNDLDKLEHWPEQVKTMQRNWIGKSRGMTVRFAVSDDSKQGLEGDYARFLQVYTTRPDTLMGATYVAVAAEHPLATAAAADKPELQAFIAECKAGSVAEADMATMEKKGVPTGRYVVNPLNGDKLEVWIANYVLWGYGDGAVMAVPAHDERDFEFATKYSLPKKQVIAVGDNAFDANQWQEWYGDKENGVLVNSGDLDGMNFQTAFDAIAAKLQSQGAGEPKTQYRLRDWGISRQRYWGCPIPIVHCEQCGDVPVPADQLPVVLPENVVPDGMGSPLAKMPEFYETACPCCGGAAKRETDTMDTFMESSWYFFRYMSPKFSDGMVSAEAAKYWGAVDQYIGGIEHAILHLLYARFFTKLMRDEGLVNVDEPFERLLTQGMVVCETYYRENDKGGKDWINPADVELTFDDKGRPVSAVLKADGLPVVISGTEKMSKSKNNGVDPQELINAYGADTARLFMMFAAPPEQSLEWSDSGVEGAHRFLRRLWRTVYEYLKQGGAVKAFAGNQDGLSKELKDLRHKLHSTIAKVSDDYGRRQQFNTAIAAVMELLNQYDKTDTGSEQGRAVAQEVLETAVRLLWPIVPHICETLWSELNGAKLWEAGWPAVDEAALVKSEIEVMVQVNGKLRGKITVAADASKADLEAAALATEGAVKFMEGKPAKKIIVVPGRLVNIVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRD3_CAEEL
Sequence: MNATNLQLISHAQKIDHVFKIIGYIVNPLGILFNTLLIILISTKTPKLLQSYSMLHLNFALCDLFSCLAGMLALQKIVFSGWSLTYIFHGACGQISSYFCYFLHVFVCHCLAHSQWILMISFLYRYYILDQISPDTVKIVRICILTYLPSLLFVIVYWSDVANEDALKRIVNSFHPEYIYDSKEIWGDLVIAGNMSCWSAATFSAIVYMTIPCFPIYGVIVFFRHKTLKSLDGRGRITMSETTRSSHKQLIKALTIQAIVPIFWLTASTFYLLALFQVVGRVIVENMPFRIMECMPMITPLISLYFVRPYRSALTGWFFPTSLLKPVIASAMLSSTAASVAPTP
What are the official names of this protein?
Serpentine receptor class delta-3, Protein srd-3.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein srd family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: AF101_ALTAL
Sequence: MSYFFGSTVPFAEPLWYSRPENFRYNESHRRLRESVRGYIEAEIMPFCTQWEADGEVPSHVLKRHAALGYAAALINPSAVKEHMHDVRLPGDVPPREWDEFHGLIVADEVARCGSLGVLWALGCGTAIACPILVNYGTEEQKAKFLPPVIHGESRFCLGITEPEVGSDIANLVTRAEQEGNYFIVNGTKKWVTNGTFADYCIAAVRTGQAGRTGISLLNIPLDVAGVSREKIESSGVASGGTASITFDNVQVPVENLLGEKNKGFYMLMSSFDHHRSWIAANCLRLARVCLEDAYQYALTRQTFGKPLINHQTIRLKLANIGIQITSSYALLESLTEMRQNLSVKMGQVHRGIGGLCAITKVAAARTFELAVRESQQIMGASAYTRTGPGLRVERLSRDMRVLVIGGGSEEILSEMSVVQEQKDLNRCKSCP
What is the function of this protein?
Acyl-CoA dehydrogenase; part of the gene clusters that mediate the biosynthesis of the host-selective toxins (HSTs) AF-toxins responsible for Alternaria black spot of strawberry disease by the strawberry pathotype (Ref. 1).  AF-toxin I and III are valine derivatives of 2,3-dyhydroxy-isovaleric acid and 2-hydroxy-isovaleric acid respectively, while AF II is an isoleucine derivative of 2-hydroxy-valeric acid (PubMed:15066029, Ref. 1, PubMed:22846083).  These derivatives are bound to a 9,10-epoxy-8-hydroxy-9-methyl-decatrienoic acid (EDA) moiety (PubMed:15066029, Ref. 1, PubMed:22846083).  On cellular level, AF-toxins affect plasma membrane of susceptible cells and cause a sudden increase in loss of K(+) after a few minutes of toxin treatment (PubMed:22846083).  The aldo-keto reductase AFTS1 catalyzes the conversion of 2-keto-isovaleric acid (2-KIV) to 2-hydroxy-isovaleric acid (2-HIV) by reduction of its ketone to an alcohol (PubMed:15066029).  The acyl-CoA ligase AFT1, the hydrolase AFT2 and the enoyl-CoA hydratases AFT3 and AFT6, but also the polyketide synthase AFT9, the acyl-CoA dehydrogenase AFT10, the cytochrome P450 monooxygenase AFT11 and the oxidoreductase AFT12 are all involved in the biosynthesis of the AK-, AF- and ACT-toxin common EDA structural moiety (PubMed:12019223, Ref. 1, PubMed:18986255).  The exact function of each enzyme, and of additional enzymes identified within the AF-toxin clusters have still to be determined (PubMed:12019223, Ref. 1, PubMed:18986255).
What are the official names of this protein?
Acyl-CoA dehydrogenase AFT10-1, AF-toxin biosynthesis protein 10-1.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
Protein: MAZE_ECO57
Sequence: MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Labile antitoxin that binds to its cognate MazF endoribonuclease toxin and neutralizes its activity.  Both MazE and MazE-MazF bind to the promoter region of the mazE-mazF operon to inhibit their transcription.
What are the official names of this protein?
Antitoxin MazE.
What is the protein family that this protein belongs to?
Belongs to the PemI family.
Protein: SEPF_CLOB6
Sequence: MSGKILDKMAGLLGLEDDLEEDLEEVEEETAEEEVTPLISSNTKRNNKVVSIHTAVSAKVKIIKPCSYEEAVDICDELKNRKIIIVNTTDLETKIAQRLLDFMGGASYALGGSLEEVEKSVYILAPSTVEVTNELKSQLISSKGIFNWNK
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: MRAY_STRGC
Sequence: MHTAIIAGITTFILTIIGIPAFIRFYQKARISGQQMHEDVKQHQAKAGTPTMGGTVFLLASIVASFVIALFSGNLSSNVTTILFILFLYGLVGFLDDFLKVFRRINEGLNPKQKLFLQLVGGVVFYLFFERHGGGDMLNVFGFPLELGFLYIFFVLFWLVGFSNAVNLTDGIDGLASISVVISLGAYAVIALEQKRFDLLIVIFSMIGGLLGFFGFNHKPAKIFMGDVGSLALGGMLAALSIALHQEWTLLLIGIVYVFETASVMLQVTYFKMTGGKRIFRMTPVHHHFELGGFSGRGKAWSEWKVDFLFWGIGLVASLITLAILYL
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL4_HALHL
Sequence: MELKLSNEKGEAAGQLEVSDQAFDAPFRESLVHQVVTAHLAGARAGTKAQKTRSEVAGGGKKPWRQKGTGNARAGTIRSPLWRGGGQTFAAKPRDFSQKVNRKMYRGALRSILSELARQDRLVVVKQLTVDAPKTRELKARLEGLGVREGLIVVDEIDANLELAARNLPRLGVVDAAGVDPASLVGAERVVITESAIRRVEEWLS
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: ARMET_DROSI
Sequence: MKTWHMVVVIGFLATLAQTSLALKEEDCEVCVKTVRRFADSLDDSTKKDYKQIETAFKKFCKAQKNKEHRFCYYLGGLEESATGILNELSKPLSWSMPAEKICEKLKKKDAQICDLRYEKQIDLNSVDLKKLKVRDLKKILNDWDESCDGCLEKGDFIKRIEELKPKYSRSEL
What is the function of this protein?
Required during the maturation of the embryonic nervous system for maintenance of neuronal and cuticular connectivity.  Essential for maintenance of dopaminergic neurons and dopamine levels (By similarity).
What are the official names of this protein?
Mesencephalic astrocyte-derived neurotrophic factor homolog, MANF/CDNF-like protein.
What is the protein family that this protein belongs to?
Belongs to the ARMET family.
What are the subcellular locations of this protein?
Secreted.
Protein: VF257_ASFM2
Sequence: MYSVCDVVRDAVAQSHLCACPNDKLPQCKGVTKAPPECSVFHLAKLQDTKFKWKYTLDPLKAQKLDQINKDIEKDAITLKLIYGTELSPEDVEWWKMQRCLINKNTGAKGGQFAHKYLERQDLELLGYSPTSLIGGDLMFTALPDKVLRTIPVVWDRFLNPAMMIFFLIILLCIILGIFYVLVRNTLRRKQKSKQHQMEIKRFIKEKEQDPYIHTSFESWPADPNKEWKELIPVYEAQGYCMADYRKKLGMPPVPNC
What are the official names of this protein?
Transmembrane protein C257L, pC257L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus C257R family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein. Virion.
Protein: YCLF_BACSU
Sequence: MASIDNESIIKSVPQKGFFGHPRGLFTLFFTEFWERFSYYGMRAILLYYLYTETVNGGLGFDKGTAVAIMSIYGSLVYMSTIIGGWLADRVFGTANTVFYGGIFIMFGHIALAYPGSSIAFYISMVLIIVGTGLLKPNVSSVVGDLYTKEDPRRDSGFSIFYMGINLGGLLAPLIVGTLGQKYNYHLGFGAAAVGMLLGLIVFALTRKKNLGLAGSNVPNPLSKKSAIGTGIGVIIVAIAVIISVQTGVLTIKRFIDLVSILGILIPVIYFIIMFTSKKADKTEKSRLAAYVPLFIGAVMFWAIQEQGATILAVYADERIRLSLGGFELQSSWFQSLNPLFVVIFAPIFAWLWMKLGKRQPSTPVKFSIGIILAGLSFIIMVFPAMQGKEALVSPLWLVLSFLLVVLGELCLSPVGLSVTTKLAPAAFSAQTMSMWFLTNAAAQAINAQVAGLFDKIPETMYFGTIGLISIVLGGILLLLSPVIKRAMKGVL
What are the official names of this protein?
Uncharacterized transporter YclF.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YCIB_BRADU
Sequence: MDKTQPHPLFKLATELGPLLVFFFVNAKFNLFAATGAFMVAIVAAMIASYVVTRHIPIMAIVTGVIVLVFGTLTLVLHDETFIKVKPTIIYGLFAAILGGGLLFGRSFIAVMFDQMFNLTPQGWRILTLRWALFFAGMAVLNEIVWRTQSTDFWVNFKVFGVTPITMIFAIAQMPLTKRYHLEPVSLEASEADAGDVRKG
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL22_RICBR
Sequence: MVQENKNFATAKAKSIRVSPRKLNLVAAFIRNMKVSEALVQLTFSPKRISKVVKACLQSAVANAENNLGLDIDRLVITNATVGKALVMKRVMPRAKGRATRINKFFSNLYITVTEKEDN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: GCST_ANOFW
Sequence: MLQRTPLFPLYAEYGAKTIDFGGWELPVQFSSIKEEHEAVRTRAGLFDVSHMGEFEVKGKDSVAFLQKMMTNDVAKLTDGRAQYTLMCYEDGGTVDDLLVYKKADDHYLLVVNAANIEKDFAWLSEHVVGDVELVNISNDIAQLALQGPLAEKVLQQLTTVDLSTMKFFAFADHVDVAGVQTLVSRTGYTGEDGFELYCRAEDAPTLWRAILEAGKEEGVLPCGLGARDTLRFEACLPLYGQELAKDITPIEAGLGFAVKTNKDVDFFGKEILKKQKEEGAPRRLVGIEMIDKGIARHGYAVYVNNEQIGFVTTGTQSPTLKKNIGLALISTAFSSLDTEVEVDVRGKRLKARVVATPFYKRTK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: STXA_SHIDS
Sequence: MKIIIFRVLTFFFVIFSVNVVAKEFTLDFSTAKTYVDSLNVIRSAIGTPLQTISSGGTSLLMIDSGTGDNLFAVDVRGIDPEEGRFNNLRLIVERNNLYVTGFVNRTNNVFYRFADFSHVTFPGTTAVTLSGDSSYTTLQRVAGISRTGMQINRHSLTTSYLDLMSHSGTSLTQSVARAMLRFVTVTAEALRFRQIQRGFRTTLDDLSGRSYVMTAEDVDLTLNWGRLSSVLPDYHGQDSVRVGRISFGSINAILGSVALILNCHHHASRVARMASDEFPSMCPADGRVRGITHNKILWDSSTLGAILMRRTISS
What is the function of this protein?
The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits.  After endocytosis, the A subunit is cleaved by furin in two fragments, A1 and A2: A1 is the catalytically active fragment, and A2 is essential for holotoxin assembly with the B subunits (By similarity).
What are the official names of this protein?
Shiga toxin subunit A.
What is the protein family that this protein belongs to?
Belongs to the ribosome-inactivating protein family.
Protein: TRPB_SALEP
Sequence: MTTLLNPYFGEFGGMYVPQILMPALNQLEEAFVSAQKDPEFQAQFADLLKNYAGRPTALTKCQNITAGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHALAHALKMMREQPEKEQLLVVNLSGRGDKDIFTVHDILKARGEI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: STS1_PYRTR
Sequence: MNVQYQAFTPPHLLNNTRRSPTRNISSLSSTMSGRKRKAEDDGSAGDDDRMSASPSASPAVLPRPAPRGMKRMRTNISGRPLPLPRLLETLSPDDMRNLLQSICQRHPDISNEIVTTAPRPSIQSTLEVLAKYEASFQAAFPFGGRASSDYAYNRVRQQLDELLDSLKDFTPHFLPPNEQQPATSLTFLDGATNIIHRLPNWDTFQHNRHKQEAYEEMAKAWAMVIQEAAKKAGGIQLQYGGWDEKIAKHNEISGGKMQEAVNELRGGLGWMGAETSNSAAGAPADAMSIRQQLLSGNYGAGSPASIGAW
What is the function of this protein?
Involved in ubiquitin-mediated protein degradation.  Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates.  Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).
What are the official names of this protein?
Tethering factor for nuclear proteasome sts1.
What is the protein family that this protein belongs to?
Belongs to the cut8/STS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DB113_HUMAN
Sequence: MKILCIFLTFVFTVSCGPSVPQKKTREVAERKRECQLVRGACKPECNSWEYVYYYCNVNPCCAVWEYQKPIINKITSKLHQK
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 113, Beta-defensin 13, DEFB-13, Defensin, beta 113.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARAA_SALG2
Sequence: MTIFDNYEVWFVIGSQHLYGAETLRQVTQHAEHVVNALNTEAKLPCKLVLKPLGTSPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLSILNKPLLQFHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHSVVTGHWQDKEAHTRIGAWMRQAVSKQDTRQLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNAISDGDINALIDEYESSYTLTPATRIHGDKRQNVREAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAVEEKPILDVQHLGIGGKEDPARLIFNTQTGPAIVASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHHTVFSHALDLNDMRQFAEIHDIEIAVIDNDTRLPAFKDALRWNEVYYGFKR
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: MURA_ACTP2
Sequence: MEKFRVHGPFTLSGTVDISGAKNAALPILFAAVLATEPVTLTNVPDLKDVDTTFKILRKLGVVVERDESGAVQIDASKIDHYVAPYELVKTMRASIWALAPLVARFHEGQVSLPGGCTIGARPVDMHISGLEKMGALIELDEGYVKATSNGRLHGARIYMDKVSVGATLSVMMAATLAEGTTTIENAAREPEIVDTALFLNAMGAKISGAGTDTITIEGVERLTGCQHRIVADRIETGTFLVAAAVSGGKITCRGTKADTLEAVIEKLREAGMEVTVTEDTITLDSKGQRPKAVNIRTMPHPGFPTDMQAQFTLLNVVAEGTSRITETIFENRFMHIPELNRMGAKGEIEGNTAICHGVEKLKSAEVMATDLRASISLVLAGCIASGETIVDRIYHIDRGYEHIEDKLRGIGAKIERFSTKFEE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_NEIG2
Sequence: MSEIKTDDPKRGIKLRGADKTARIPIKVVPLQEKLKKPEWIRAKLPSRKFFEIKDILREQKMHTVCEEASCPNIGECFSKGTATFMIMGDICTRRCPFCDVGHGRPNMLDPDEPKNLAESVKAMNLRYVVITSVDRDDLRDGGAQHFADCIKAIRETSPNTKIEILVPDFRGRLDIALKILAETPPDVMNHNLETHPSLYRKARPGANYQHSLDLLKRYKEMMPHIPTKSGIMVGLGETDEDVREIMRDMRAHNIEMITIGQYLQPSDGHLPVLRYVTPEQFKIFEKEAYELGFTNAAIGAMVRSSYHADEQAAEALRESHGGCGHH
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLE4_CONCL
Sequence: MKFLLFLSVALLLTSFIETVTVNKAGMERPSRALVGRGCPAECPDTCSSSGSCAPDFIG
What are the official names of this protein?
Conotoxin Cl14.4.
What are the subcellular locations of this protein?
Secreted.
Protein: RESA_BACAH
Sequence: MKKNRLLFRVIILLILSGAVGFTLYQGFFADKEKMQIGKEAPNFVVTDLEGKKIELKDLKGKGVFLNFWGTWCKPCEKEMPYMNELYPKYKEKGVEIIALDADETDIAVKNFVNQYGLKFPVAIDKGQKIIGTYGVGPLPTSFLIDKDGKVVEQIIGEQTKEQLEGYLKKITP
What is the function of this protein?
Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis.  May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached.
What are the official names of this protein?
Thiol-disulfide oxidoreductase ResA.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. ResA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane.