PharMolix/UniProtQA huggingface dataset:
Protein: RSBW_STAAC
Sequence: MQSKEDFIEMRVPASAEYVSLIRLTLSGVFSRAGATYDDIEDAKIAVSEAVTNAVKHAYKENNNVGIINIYFEILEDKIKIVISDKGDSFDYETTKSKIGPYDKDENIDFLREGGLGLFLIESLMDEVTVYKESGVTISMTKYIKKEQVRNNGERVEIS
What is the function of this protein?
Negative regulator of sigma-B activity.  Phosphorylates and inactivates its specific antagonist protein, RsbV.  Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B) (By similarity).
What are the official names of this protein?
Serine-protein kinase RsbW, Anti-sigma-B factor, Sigma-B negative effector RsbW.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: C1QRF_HUMAN
Sequence: MLLVLVVLIPVLVSSGGPEGHYEMLGTCRMVCDPYPARGPGAGARTDGGDALSEQSGAPPPSTLVQGPQGKPGRTGKPGPPGPPGDPGPPGPVGPPGEKGEPGKPGPPGLPGAGGSGAISTATYTTVPRVAFYAGLKNPHEGYEVLKFDDVVTNLGNNYDAASGKFTCNIPGTYFFTYHVLMRGGDGTSMWADLCKNGQVRASAIAQDADQNYDYASNSVILHLDAGDEVFIKLDGGKAHGGNSNKYSTFSGFIIYSD
What is the function of this protein?
May regulate the number of excitatory synapses that are formed on hippocampus neurons.  Has no effect on inhibitory synapses (By similarity).
What are the official names of this protein?
C1q-related factor, C1q and tumor necrosis factor-related protein 14, C1q/TNF-related protein 14, Complement component 1 Q subcomponent-like 1.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPA_HAEIG
Sequence: MQLNSTEISELIKKRIAQFDVVSEARNTGTIVSVSDGIIRIHGLSDVMQGEMIALPGNRYAMALNLERDSVGAVVMGPYADLAEGMEVQCTGRILEVPVGRGLLGRVVNTLGQPIDGKGEIDNDGFSPVEVIAPGVIDRRSVDQPVQTGYKAVDSMVPIGRGQRELIIGDRQTGKTALAIDAIINQRNSGIKCIYVAIGQKASTIANVVRKLEEHGALANTIVVAASASESAALQYLAPYAGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERASRVNEDYVEKFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLFNSGIRPAVNPGISVSRVGGSAQTKVIKKLAGGIRTALAQYRELAAFAQFASDLDDATRKQLSHGEKVTELLKQKQFAPLSVAEQAVILFAVEFGYLDDVELSKIASFETALLDYSNRNHAEFMQELNKTGNYNDEIKDTLKSILDGFKANSAW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL10E_THEON
Sequence: MGLRPAKIDRDVDKPAYTRREYIRGAPGPKITIFDMGNLSAEFQYEVSLHAEQAMQIRQNALEAIRIQVNRYLQKNVGRSNYHFKIRVYPFQVLRENPMATGRKADRYGNGMRRPFGKPIGLAARVKKDQKILTVWVNEGHLKFALEAMRRAAMKLPYSAYYRIYDKEGNDITSKVLSTMKR
What are the official names of this protein?
50S ribosomal protein L10e.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: XNI_ALIFM
Sequence: MAIHLVIIDALNLIRRVHSAQPNQDDIQAVITTTTRTINKILKETEPTHIIAVFDHHLQDRGWRAEILPQYKEDRKPMPEALQKGMDDIQEAWWKLGIDSLLSDGDEADDLVATLANKVAVHNEQVTIISTDKGYCQLLSPTLRIRDYFQHRWLDAPFVEKEFGLKPEQLADYWGLAGISSSKITGIPGVGPKAALEILTQFPTIEAANESEDLPKKYRKKFDEHYETAILCRQVAGLRTDIELGFNLQDIRYEKGTRDYQV
What is the function of this protein?
Has flap endonuclease activity.  During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
What are the official names of this protein?
Flap endonuclease Xni, FEN.
What is the protein family that this protein belongs to?
Belongs to the Xni family.
Protein: NCX6_CAEEL
Sequence: MRIHFFAFLIILSLVGCDGWQADVGKLVRKWNNQRTIDGNDIEKCIPDDGEQCTIQAGWNSTQVCEYVKCNDDNCEGGGYVLWTRYVECASSPAVRIILIITGVIYMLVLFIMVSSAADDFFSPSISSIVAHLRISESVAGVTFMAFGNGAPDVFGAIASVLSSPTPKADLALGELFGAGLFVTTMVLAVTIFTRPFKAEVFSSIRDIAFYLVALAFLAFCFVYYDHVEIWMPITFLGVYLIYVCTVILSQILHNRHKKDEEKVDEVKTVDTDSLEDDDDIYVSHGHHVLHAHEVMKMEAEIEAVEPLKTWSFRGVVHDFKEHLKPWPSMDEWDEMNIFQKVIAVLNTIPNFLFKLTIPHSEQPWSKPITLLQCLICPVFLLFCIQVCSISPFPNSPGLWMYGLILSVLLTAAVLFFTELHKEPPFYKSLISYAGFLMSIAWIYLISSEVVNVVTMLGVVSRVSHEVLGLTILAWSNSIGDLIADVSVAKQGYPRMAMAAAIGGQLFNLLIGFGLPFTIAKIQGKSISMIINPTYRLLMLFLAISLIFTLIAMFAQKYFLRRIHSYSLVFIYISFFVFIGLSLDDILVWN
What are the official names of this protein?
Putative sodium/calcium exchanger 6, Na(+)/Ca(2+)-exchange protein 6.
What is the protein family that this protein belongs to?
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PSA_ACTMD
Sequence: MTMPLYASPEQILRDRSEYARKGISRGRSVVVLRYADGVLFVAENPSSTLHKVSEIYDRIGFAAVGRYSEFENLRQAGIRFADVRGYQNDPRDVTGRSLANVYAQTLGSIFTEQIKPLEVEICVAEVGHTPEHDTLYRLTYDGSIVEEPQHSVMGGQAETTATALKESYEEGLPLAAALRVAVKALSAGSASTGNGKPELLEAANLEAAVLERDRPRRAFRRLKGTALAALLQDTPPDDADADADAGKKPANDGNLPPNDDKS
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PrcA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPD_ECOLC
Sequence: MQQLQNIIETAFERRAEITPANADTVTREAVNQVIALLDSGALRVAEKIDGQWVTHQWLKKAVLLSFRINDNQVIEGAESRYFDKVPMKFADYDEARFQKEGFRVVPPAAVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYIGQSTRIYDRETGEIHYGRVPAGSVVVSGNLPSKDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_BACFR
Sequence: MIRFLGNIEAKADAKGRVFIPAQFRRQLQSGSEDKLIMRKDVFQDCLVLYPEEVWNEELDELRQRLNKWNANHQLIFRQFVSDVEIITMDGNGRILIPKRYLQITGIQSDVRFIGVDNKIEIWAKERAEKLFMEPKAFGAALEEIMKEERRTTNNELK
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: DAPD_ACIBC
Sequence: MSQLSTIIEQAFEDRANFTAADCPSEIRQAVEEAIAGLDNGTLRVAEKINGEWVVHQWLKKAVLLSFKLNDNKPIESCDLRFYDKVETKFSGWTEEQFKAAGVRVVPPAVARRGSFQAKNVVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVEEGSVISMGVYIGQSTRIYDRETGEIHYGRVPAGSVVVPGNLPSADGKYSLYAAIIVKKVDAQTRAKTSLNDLLRAD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTPC1_DANRE
Sequence: MAAGVSLVSDLPYSTSRESNTDMETVNVRVPTAKYTKVGETLRHVIPGHMQCSMACGGRACKYENPSRWSDKEQAVKGLYSSWITDHLLAMARPSTEIVEKFNIIEQFHVCGLKTVINLQRPGEHASCGSTLEPESGFTYRPELFMEAGIYFYNFGWKDYGVASLTTILDMVKVMSFAMQEGKIAVHCHAGLGRTGVLIACFLVFTSRMSADQAILFVRAKRPNSIQTRGQLLCVREFAQFLVPLRSVFSCAEPKAHEVTLSQYLTRQRHLLHGYEARHMKNMPKIIHLICRLLLDIAENRQTVEEEVLEIPDLTEEVEKTVSLQALQQLGKEMRGKGIPISSPRSPDQPNLLGTPCDPPHDQPLCSDQEFDVLWRWPTVDNTYRSRLILSKCFSYSDSALHKLDPRVHVLQSPQNLSSKSGLNFSELYASQSRLALETPDLLPSDIKSSPKHDLLTGSRSSLVQSKKIEEQVSCPPASVKQAPLKVAKRSMSYGFLGRTNDSSTMFSICQVGRSTNKNSNCDVTQHFKDVPILTLQSELSPETRHLFVAKALTVDLDGEELRSKVSVWQMELNSREGAWERLCNERDPVVLSLLMWSWLEQLKEPVITKDDVETLSGNRLNPEHALNSLDKGQKQTLLCILDCAAHLLKIPEEVENAFFERLIKAFTWISSDSENGQLIYKALKDVMVPVLRDLRTKAMEELEFTCHCSFVP
What is the function of this protein?
May play roles in cilia formation and/or maintenance.
What are the official names of this protein?
Protein tyrosine phosphatase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class PTPDC1 subfamily.
Protein: SECG_HELPY
Sequence: MTSALLGLQIVLAVLIVVVVLLQKSSSIGLGAYSGSNESLFGAKGPASFMAKLTMFLGLLFVINTIALGYFYNKEYGKSVLDETKTNKELSPLVPATGTLNPALNPTLNPTLNPLEQAPTNPLMPQQTPNELPKEPAKTPSVESPKQNEKNEKNDAKENGIKGVEKTKENAKTPPTTHQKPKTHATQTNAHTNQKKDEK
What is the function of this protein?
Involved in protein export.  Participates in an early event of protein translocation (By similarity).
What are the official names of this protein?
Protein-export membrane protein SecG.
What is the protein family that this protein belongs to?
Belongs to the SecG family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FENR_STRPC
Sequence: MKDKAYDITIIGGGPIGLFAAFYAGLRGVTVKIIESLSELGGQPAILYPEKMIYDIPAYPSLTGVELTENLIKQLSRFEDRTTICLKEEVLTFDKVKGGFSIRTNKAEHFSKAIIIACGNGAFAPRTLGLESEENFADHNLFYNVHQLDQFAGQKVVICGGGDSAVDWALALEDIAESVTVVHRRDAFRAHEHSVELLKTSTVNLLTPYVPKALKGIGNLAEKLVIQKVKEDEVLELELDSLIVSFGFSTSNKNLKNWNLDYKRSSITVSPLFQTSQEGIFAIGDAAAYNGKVDLIATGFGEAPTAVNQAINYIYPDRDNRVVHSTSLID
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: RSGA_MARN8
Sequence: MAKRRLNKRQQWRIEKIQKERTVRAARKEKAVEEQAAAGELGPEQNGLVIAHYGQQLDIEALEGPESGQVFRCFVRANIDSLVTGDRVVWRPGKSKTGVIVARCERENLLQRPDNFGALKPVAANIDHIILVIAPEPEPHDNLIDRYLVASESSDIPAVILLNKTDLINDDNRDQIEALLARYQALGYEVARTSAAETAGTPAPEVEALVRNQTSVFVGQSGVGKSSIIQTLLPDELLRVGAVSESTGKGVHTTTTAKLFHLPGGGDLIDSPGIREFGLWHMTPQEVEYGFREIRPLIGLCKFRNCRHMGDPGCALDAAAEAGDISPERLKSFHRILQDMTDQQARGLKLT
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U17L3_HUMAN
Sequence: MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALASGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ
What is the function of this protein?
Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular response to viral infection.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 17-like protein 3, Deubiquitinating enzyme 17-like protein 3, Ubiquitin thioesterase 17-like protein 3, Ubiquitin-specific-processing protease 17-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP17 subfamily.
What are the subcellular locations of this protein?
Nucleus. Endoplasmic reticulum.
Protein: CAMT_MEDSA
Sequence: MATNEDQKQTESGRHQEVGHKSLLQSDALYQYILETSVFPREHEAMKELREVTAKHPWNIMTTSADEGQFLSMLLKLINAKNTMEIGVYTGYSLLATALAIPEDGKILAMDINKENYELGLPVIKKAGVDHKIDFREGPALPVLDEMIKDEKNHGSYDFIFVDADKDNYLNYHKRLIDLVKVGGVIGYDNTLWNGSVVAPPDAPLRKYVRYYRDFVLELNKALAVDPRIEICMLPVGDGITICRRIK
What is the function of this protein?
Methylates caffeoyl-CoA to feruloyl-CoA and 5-hydroxyferuloyl-CoA to sinapoyl-CoA.  Plays a role in the synthesis of feruloylated polysaccharides.  Involved in the reinforcement of the plant cell wall.  Also involved in the responding to wounding or pathogen challenge by the increased formation of cell wall-bound ferulic acid polymers.
What are the official names of this protein?
Caffeoyl-CoA O-methyltransferase, Trans-caffeoyl-CoA 3-O-methyltransferase, CCoAMT, CCoAOMT.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. CCoAMT subfamily.
Protein: KNG_GADMO
Sequence: RHEVPQANLECDEGAMDLKISTGNMVALYQILSASKDSDCPAGGAVTWTDQVVAGLRICMGCPVELDLESEELKVPVAVSISKRRPPGWSPLRAAVTSFNEKEFSPPAPPSRAEYSLYFDMRK
What is the function of this protein?
Inhibits papain and ficin (cysteine proteinases) but not trypsin (a serine proteinase).
What are the official names of this protein?
Kininogen.
Protein: LAC15_ORYSJ
Sequence: MKRCQSSRPTAAVAAVVAAVSMIIVLVSGTAIPSAAAAAAVEHTFVVSQVNMTHLCKEMAFTVVNGQLPGPTIEVTEGDSVTVHVVNKSPYNLTIHWHGVYQLLNCWNDGVPMITQRPIQPNHNFTYRFNVAGQEGTLWWHAHDAFLRGTVHGALIIRPRHGAASYPFPRPHREVPIIIGEWWEKDLPQVDRNMTNGYFDDYSSGSTINGKLGDLFNCSGVLEDGYVLDVEPGKTYLLRIINAALFSEYFLKIAGHRFTVVASDANYLTPYSTDVVVIAPGETLDAIVVADAPPSGRYYIAAQPIQAPPPDTQTPEYATRGTLQYSSNSRNSSAAAMPEMPHQHDTMRSFYFRGNLTAGARLHRHGRRRVPARADESLFVTLGLGSVCRHGGASCKRGGNLKESIVVANVNNVSFHIPAAAATPILEAHYYHRLHAGAGEEEEELAERPPRAYNYTDQALTPFGPEEMRLEATSRAVVTRRFRHGATVDVVFQSTAMLQGDSNPMHLHGHDVFLLAQGIGIYDAARDEGKFNLVNPPRKNTVLVPNLGWAAVRFVADNPGAWLMHCHFEFHLSMGMAAVFIVEDGPTVDTSLPPPPEDF
What is the function of this protein?
Lignin degradation and detoxification of lignin-derived products.
What are the official names of this protein?
Laccase-15, Benzenediol:oxygen oxidoreductase 15, Diphenol oxidase 15, Urishiol oxidase 15.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: CTHR1_RAT
Sequence: MHPQGRAASPQLLLGLFLVLLLLLQLSAPSSASENPKVKQKALIRQREVVDLYNGMCLQGPAGVPGRDGSPGANGIPGTPGIPGRDGFKGEKGECLRESFEESWTPNYKQCSWSSLNYGIDLGKIAECTFTKMRSNSALRVLFSGSLRLKCRNACCQRWYFTFNGAECSGPLPIEAIIYLDQGSPELNSTINIHRTSSVEGLCEGIGAGLVDVAIWVGTCSDYPKGDASTGWNSVSRIIIEELPK
What is the function of this protein?
Its overexpression in smooth muscle cell lines increases their migratory ability and inhibits collagen type I expression.  May act as a negative regulator of collagen matrix deposition.
What are the official names of this protein?
Collagen triple helix repeat-containing protein 1.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: YSL8_ARATH
Sequence: MRKGGLTPDRDRQIEEHELQETGISPDIERLKRNINATPYQREEEEEDREEQEESVEGIFESREVPSWKKQLTIRAFVVSFALSILFSFIVMKLNLTTGIIPSLNVSAGLLGFFFVKTWTKMLHKSGLLKQPFTRQENTVIQTCVVASSGIAFSGGFGTYLFAMSHRIADQSGDVARGVKDPSLGWMIAFLFVVSFLGLFSVVPLRKIMIIDFKLPYPSGTATAHLINSFHTPQGAKLAKKQVRVLGKFFSFSFFWGFFQWFFTAGENCGFNSFPTFGLRAYQYKFYFDFSATYVGVGMICPYIINISLLLGGILSWGLMWPLIETRKGDWFPSNVDSSSMNGLQAYKVFIAVATILGDGLYNFCKVLIRTFSGLISQIRGKAGSRSSLAHKEDPPASPASPLTPRISYDDQRRTRFFLKDQIPSWFAVGGYVVISAVSTAILPHMFSQLRWYYIIVIYIFAPILAFCNAYGAGLTDWSLASTYGKLAIFTIGAWAGSDHGGLLAGLAACGVMMNIVSTASDLTQDFKTGYLTLSSPRAMFVSQVIGTAMGCLVSPCVFWLFYKAFDDLGLPNSEYPAPFATVYRSMAKLGVEGVSSLPRDCLMLCYVFFGVAILINLIKDCLGNRWGRFVPLPMAMAIPFFLGPYFAIDMCVGSFILFVWERLDAPKAEAFATAVASGLICGDGIWTLPSSVLAIAGVKPPICMKFLSAATNHRVDKFLQGSS
What is the function of this protein?
May be involved in the transport of nicotianamine-chelated metals.
What are the official names of this protein?
Probable metal-nicotianamine transporter YSL8, Protein YELLOW STRIPE LIKE 8, AtYSL8.
What is the protein family that this protein belongs to?
Belongs to the YSL (TC 2.A.67.2) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: COX5B_YEAST
Sequence: MLRTSLTKGARLTGTRFVQTKALSKATLTDLPERWENMPNLEQKEIADNLTERQKLPWKTLNNEEIKAAWYISYGEWGPRRPVHGKGDVAFITKGVFLGLGISFGLFGLVRLLANPETPKTMNREWQLKSDEYLKSKNANPWGGYSQVQSK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of COX2 and heme A of COX1 to the active site in COX1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 5B, mitochondrial, Cytochrome c oxidase polypeptide Vb.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase IV family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: APOA2_MACMU
Sequence: QAEEPSVESLVSQYFQTVTDYGKDLMEKVKSPELQAQAKAYFEKSKEQLTPLVKKAGTDLVNFLSYFVELRTQPATQ
What is the function of this protein?
Apo A-II makes up about 20% of the protein of the HDL (high density lipoprotein) phospholipid-rich fraction in plasma.
What are the official names of this protein?
Apolipoprotein A-II, Apo-AII, ApoA-II, Apolipoprotein A2.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MYO1A_MOUSE
Sequence: MPLLEGPVGVEDLILLEPLDEESLIKNLQLRYENKEIYTYIGNVVISMNPYEQLPIYGPEFIAKYRDYTFYELKPHIYALANVAYQSLKDRDRDQCILITGESGAGKTEASKLVMSYVAAVCGKGEQVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKSRVVKQLKGERNFHIFYQLLAGADAQLLKALKLEEDTSVYGYLNGEVSKVNGMDDASNFRAVQHAMSVIGFSEEEIRQVLEVTALVLKLGNVKLTDEFQANGIPASGICDGKGIQEIGEMMGLNSTELERALCSRTMETGKEKVVTVLNVTQAQYARDALAKNIYSRLFDWIVKRINESIKVGTGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNERLQQVFIELTLKEEQEEYKREGIPWTKVEYFDNGIICNLIEHSQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHSHYESKVSQNAQRQYDRTMGLSCFRISHYAGKVTYNVTGFIDKNNDLLFRDLSQTMWKAQHPLLKSLFPEGNPKEASLKRPPTAGTQFKNSVAVLMKNLYSKNPNYIRCIKPNDQQQKGRFTSEMVMVQARYLGLLENVRVRRAGYAFRQGYKPFLERYRLLSRSTWPRWNGDDREGVEKVLGSLTLSSEELAYGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKVYRGWRCRTHYQQMRKSQILISAWFRGNKQKKHYGKIRSSVLLIQAFVRGWRARKNYRKYFRSGAALTLANFIYQSMAQKFLLNLKKNLPSTKVLDNTWPAAPYRCFNTANQELQRLFYQWKCKKFRDQLSPKQVQTLREKLCASELFKGKKASYPQSVPIPFRGDYIGLQGNPKLQRLKGREEGPVLVADTVKKVNRGNGKTSARILLLTKGHVILTDAKKSQAQIVIGLEDVAGVSVSSLQDGLFSLHLSEMSSAVSKGDILLVSDHVVELLTKMYQAVLDATQRQLSVTVTEKFSVRFKEGSVAVKVIQGPEGGGNRKLICKKKGSNAMEVTVR
What is the function of this protein?
Involved in directing the movement of organelles along actin filaments.
What are the official names of this protein?
Unconventional myosin-Ia, Brush border myosin I, BBM-I, BBMI, Myosin I heavy chain, MIHC.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Protein: HERA_SULAC
Sequence: MTIGYIIGSATINEATAILEQKIRAGYYVILEYDGDKILGLITNVYTGSPLLDDNLNDVKFVQRIKQLEANKIPFFIKARIKLLCKLDGKFTQPDLPPVAGTPVRLASDEELSTVFSAGDVRIGKLIGSNVEVKIRLNPLSRHLAILAATGSGKSNTVAILSQRLVEIGGSILIFDYHGEYYDSTLPNLNIIEPKLNPLYLSVNEFATLLEIRENANIQYRIIRRTFNQLKEEINNEIKEGKTSLAELNSNFFERLKVKIEEEGRNEKRKESKDEVLNKVEDFAERYSDIIDITFGDVINKIKLGKINVVNLSSLDEDAIDAIVAHYLRRILTSRKENKIKKDSGLKFPILTVVEEAHVLLSKDTNTLTKKWAGRIAREGRKFGVGLIIVSQRPKGLDENILSQMTNKIILKIVEPSDKKYVLETSDNLSEDLADGLSSLDTGEAIIIGNVVKLPTIIKIDKFEGKLSGSDPNLTEEWKRAKEEEIVHSDVSDWG
What is the function of this protein?
Involved in DNA double-strand break (DSB) repair (PubMed:14990749).  Acts probably with NurA to stimulate resection of the 5' strand and produce the long 3' single-strand that is required for RadA loading (By similarity).  Exhibits DNA-dependent ATPase activity and DNA helicase activity (PubMed:14990749).  Loads on either a 3' or a 5' DNA tail for subsequent DNA unwinding (PubMed:14990749).
What are the official names of this protein?
DNA double-strand break repair helicase HerA, Helicase repair of Archaea.
What is the protein family that this protein belongs to?
Belongs to the HerA family.
Protein: LPTD_CUPNH
Sequence: MTEQRRSPNNRALPSPAPTSVPARARRAGGLHAGALRPLVLAMASLSAGAHAQMSGSAIPDLDQVEPVFEAAPKAPPLPVESGELVPRLAEPGKQSDAGSDAPTFIEADRMTGYSERGVELEGHAELRRDGGAIKGDKLTYDQDTDEAFAQGNVRMSRSGTLAVGPEARMKVEANEGYMLSPDYYFQQTGGSGKAERIDFLDKDRSTARHASYTTCSPDNADWYFSANRIDLDNDRQVGVAYGGVLNFFGVPIAAAPAFSFPLNDDRRSGFLPPLMGYGSRSGFDLTTPYYVNIAPNRDLTIYPRLMTERGLQLGGEYRYLGQGYNGRLRAEFLPDDKKTNSNRWAYSIQHNQNLAKGLNAYLNVNRVSDDQYPDDFNRSVSQSTLRQYTQEGGVTYNWQDFTFLARVQKFQTLRPSEPSYERVPQLNGKYIRYDLGGFDVQVEADYTRFRIPLTSTGFQQPQGERMFIQPSISYPIVRAGWYVTPKVTFNATQYQMEAASNTPTVQNNFSRVLPTMSLDSGMTFEREAPTVSRLFGVNYVQTLEPRLFYVYTPFRDQSQFPLFDTVQSDFGYGQIFSENPFTGYDRVADNNKLTGGLTTRLIEADTGIERFRGTIAQRYDFTGQRVQINGTLADPKAGFSDLLAATTIQMFRGYYLDAGVQYNPDSDRINYGNVAVSYRPESRKVINAGYRYRRPTSVTDNTAIDQFEVSSQWPITRRAYGIARFAFDLAASQMVDALAGVEYAADCWVGRVVYQRFRNTTQGYTGRVFLQVEFRGLSKIGSNPLNILRLNVPGYEPVSAKPVPTTQFDHYE
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: Y3177_SHEB9
Sequence: MESLQNHFLIAMPSLHDTFFERSVIYICEHDAKGAMGLVINKPLGIEVNSLLEQMDLPAEQVSTDLAFNANVMMGGPVSQDRGFVLHTSQPYWANSTDLGCGLMLTTSRDVLTAIGSNRSPEKFLVALGYAGWSKDQLEQELADNSWLTIPATNALLFDIKHEDRWPQASRALGFDAWQVSAQAGHA
What are the official names of this protein?
UPF0301 protein Sbal195_3177.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.