PharMolix/UniProtQA huggingface dataset:
Protein: FTSB_THISH
Sequence: MKWVTGLLVVLLLGLQYKLWIGEGSVAEVWQLRQTLEAQRAENEELRYRNAALDAEVTDLKTGLDAIEERARRELGMIRRDETFFQVVGRPGETP
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: MUTS_PERMH
Sequence: MKEEKNITPMLAQYHKIKDQYPDALVLYRLGDFYEMFYEDAHTGARELNIVLTKKKVGKDRYIPMCGIPFHSADSYITRLVSKGYKVAICEQLEDASKAKGIVKRDVIRVLTPGTYFENEKLKSALLGIYQERGRFYIAYLDLSTGEFTGGSLNRDELISFIGKFQPKEIVVQEGYDFSDLRSQFKSIFFSQLPEDYFSEDTHSEFLGFFKTGHISAFGFDTEEQNVIYPLSAVWKYAKVTQKSFLPFISTPKPYREDSYVRLDYSAQKHLEIVSPNEGNIPLLRVMDRTLTGMGRRKLRFFLLHPLKNSKEIIKRQNAVTELVENTELREKIRDILDQIFDIERLISKISSNTSTPRDLVGLRESLKKVSKLKEISKEIKSDLLKESFERIEDYSWLIEKLDRYLEDDPPIHLKEGGLIKKGVDKDLDELKEIKEKGNEWLKSYQEKLRKETGIQSLKIGFNKVMGYYIEVTKPNLKLVPDHFRRRQTLSNAERFITDELQSFEEKILSADEKIKALEYEIFMRIREEVAFLSDRIGKTAQQVGMIDAIQSLAQIAVEKGWTKPDIHDGYEIEIKEGYHPVIKEFMPDFVPNNLKMNRNSYFHIITGPNMAGKSTFIRQSAIIILLAQTGSYIPAKKGKIGVVDAIFTRIGSGDALAKGLSTFMVEMLEMANIVNNATERSFIVLDEVGRGTSTYDGLSIGWAISEYLAEKVKVKTLFATHYHELTQLEREIKGVKNFHMDIFEDGENIKFLYRVKEGFSNKSYGVHVAKLAGIKEQIIKRAYEILYYFEEQRDKKLEEDIYSLKQKENSYLNEINELPLFKEIEDIEKDEYRQILEEIESIDIGSITPVEALVFLNDLKKKIKRLKES
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: YCEI_SALHS
Sequence: MKKNLLGFTLASLLFTTGSAVAAEYKIDKEGQHAFVNFRIQHLGYSWLYGTFKDFDGTFTFDEKNPSADKVNVTINTNSVDTNHAERDKHLRSAEFLNVAKFPQATFTSTSVKKEGDELDITGNLTLNGVTKPVTLEAKLMGQGDDPWGGKRAGFEAEGKIKLKDFNITTDLGPASQEVELIISVEGVQQK
What are the official names of this protein?
Protein YceI.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family. Type 1 subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: TA2R1_PONPY
Sequence: MLESHLIIHFLLAVIQFLLGTFTNGIIVVVNGIDLIKHRKMAPLDLLLSCLAVSRIFLQLFIFYVNVIVIFFIEFIMCSENCAILLFINELELWLATWLGVFYCAKVASVPHPLFIWLKMKISKLVPWMILGSLLYVSMTCVFHSKYAGFMVPYFLRNFFSQNATIQKEDTPAIQIFSFVAEFLVPLLIFLVAVLLLIFSLGRHTRQMRNTVAGSRVPGRGAPISALLSILSFVILYFSHCMIKVFLSSLKFHVRSFILPFFILVIGIYPSGHSLILILGNXKLKQNAKKFLLHSKCCQ
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 1, T2R1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RSPH9_MOUSE
Sequence: MDADSLLLSLELASGSGQGLSPDRRASLLTSLMLVKRDYRFARVLFWGRILGLVADYYIAQGLSEDQLAPRKTLYSLNCTEWSLLPPATEEMAMQISVVSGRFMGDPSHEYEHTELQKVNEGEKVFDEEVVVQIKEETRLVSIIDQIDKAVAIIPRGALFKTPFGVTHVNRTFEGLPLSEVRKLSSYFHFREAIDLKNKTLLEKSDLEPSLDFLDSLEYDIPRGSWSIQMERGNALVVLRSLLWPGLTFYHAPRTKNYGYIYVGTGEKNMDLPFML
What is the function of this protein?
Functions as part of axonemal radial spoke complexes that play an important part in the motility of sperm and cilia (PubMed:30383886, PubMed:36417862, PubMed:34871179).  Essential for both the radial spoke head assembly and the central pair microtubule stability in ependymal motile cilia (PubMed:30383886).  Required for motility of olfactory and neural cilia and for the structural integrity of ciliary axonemes in both 9+0 and 9+2 motile cilia (By similarity).
What are the official names of this protein?
Radial spoke head protein 9 homolog.
What is the protein family that this protein belongs to?
Belongs to the flagellar radial spoke RSP9 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum. Cell projection, kinocilium. Note=Radial spoke.
Protein: SDH31_ARATH
Sequence: MAATALFRSIRRRDVVSAPLSVYKSLAGNAQPSWGSSYIGQNYASFSRAFGSKPVVNDILGTGLGTNNAIREEREKSKSTEAAIVGAQLTRSFRALDVGTSKRLFSTISGDIKTTQEEPKIKSFRPLSPHLSVYQPQMNSMLSIFNRISGVYLTGVTFAGYLLYLKMGMICLTYPSFYQVLYHTQQQLPVITSVTALAAIYHTIKSTHSLLTH
What is the function of this protein?
Membrane-anchoring subunit of succinate dehydrogenase (SDH).
What are the official names of this protein?
Succinate dehydrogenase subunit 3-1, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: UPPP_STRPG
Sequence: MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKAFIEMFNIVIQLGAIIAVMLIYFERLNPFQPGKTAREVQLTWQLWLKVVIACIPSILIAVPLDNWFEAHFYFMVPIAIALIVYGIAFIWIEKRNAQQEPAVTELVRMSYKTAFFIGCFQVLSIVPGTSRSGATILGAIILGTSRTVAADFTFFLAIPTMFGYSGLKAVKFFLDGHHLDFAQVLILLVASLTAFVVSLLAIRFLTDYVKKHDFTIFGKYRIVLGSLLLIYSFFKFVF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYR_METM7
Sequence: MDVENLIITTLKDKVEELTGNEMDIRLDEPPAINMGDYSTNISFRLAKDLKKAPKVIAEDIANSLNISGIEKIEAVNGYINFFMNYSDFSKETVSKIIDEKENFGKLEKRHEKVILEHTSANPNGPFHIGHGRNMVIGDSLKRILVASGYDVETQYYVNDMGRQEAIVVFGNEKFELDKSKKADHAIGEVYVETNKLLAENEELEQEILNLMKNYEEACEAGIENELTEKFKNAVDYSLGGFKETLSTLNIYHDKFVWESEFVKSGMVREVIKRLMDTGKVVEDEVFRLDLSDYGLEKKLVLARLNGTSLYSTRDIAYHINKMENCDFAVNLLGADHKLTAVMVNKTLALLGYNEAEVVFYEFISLPEGSMSTRRGRFISMDELFEEAKSRAAEEVRKRGVAESEEEIEEIAKKIAVGAVRYNIVRIAPEKPMVFRWDEALDFEKVGCPVIQYAHARCSRILENVEIISNDNLFAYEMNENEKTIVKLLSKLPKIVEKAAEVRKPQIVANYVLDVAQGFNKFYANCPVLKEENQIIKNSRIAIVNNTKMVLENTLDLLGIEMPGKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL22B_YEAST
Sequence: MESQQLHQNPHSLHGSAYASVTSKEVPSNQDPLAVSASNLPEFDRDSTKVNSQEETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWAHYQQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDSQDQHSEVPQAKTKVRNNVLPPHTLTSEENFSTWVKFYIRFLKNSNLGDIIPNDQGEIKRQMTYEEHAYIYNTFQAFAPFHLLPTWVKQILEINYSDILTVLCKSVSKMQTNNQELKDWIALANLEYNGSTSADTFEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQLFAEIQLIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYHRTNSSKPRAAKAHNIATSSKFSRVNNDHINESTVSSQYLSDDNELSLGQQQKESKPTRTIDSNDELPDHLLIDSGASQTLVRSAHYLHHATPNSEINIVDAQKQDIPINAIGNLHFNFQNGTKTSIKALHTPNIAYDLLSLSELANQNITACFTRNTLERSDGTVLAPIVKHGDFYWLSKKYLIPSHISKLTINNVNKSKSVNKYPYPLIHRMLGHANFRSIQKSLKKNAVTYLKESDIEWSNASTYQCPDCLIGKSTKHRHVKGSRLKYQESYEPFQYLHTDIFGPVHHLPKSAPSYFISFTDEKTRFQWVYPLHDRREESILNVFTSILAFIKNQFNARVLVIQMDRGSEYTNKTLHKFFTNRGITACYTTTADSRAHGVAERLNRTLLNDCRTLLHCSGLPNHLWFSAVEFSTIIRNSLVSPKNDKSARQHAGLAGLDITTILPFGQPVIVNNHNPDSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQNKQTKLDQFDYDTLTFDDDLNRLTAHNQSFIEQNETEQSYDQNKESDHDYQSEIEINSDPLVNDFSSQSINPLQLDKEPVQKVRAPKEVDADISEYNILPSTIRSRTPHIINKESTEMGGTVESDTTSPRHSSTFTARNQNRPGSTNEMIDLTSQDRVNYGLENIKTTRLGGTEEPYIQRNSDTNIKYRTTNSTPSIDDRSSNSESTTPIISIETKAVCDNTPSIDTDPPEYRSSDHATPNIMPDKSSKNVTADSILDDLPLPDLTHKSPTDTSDVSKDIPHIHSRQTNSSLGGMDDSNVLTTTKSKKRSLEDNETEIEVSRDTWNNKNMRSLEPPRSKKRINLIAAIKGVKSIKPVRTTLRYDEAITYNKDNKEKDRYVEAYHKEISQLLKMNTWDTNKYYDRNDIDPKKVINSMFIFNKKRDGTHKARFVARSDIQHPDTYDSDMQSNTVHHYALMTSLSIALDNDYYITQLDISSAYLYADIKEELYIRPPPHLGLNDKLLRLRKSLYGLKQSGANWYETIKSYLINCCDMQEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGEGDNEIQYDILGLEIKYQRSKYMKLGMEKSLTEKLPKLNVPLNPKGKKLRAPGQPGHYIDQDELEINEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH
What is the function of this protein?
Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane.  Once in the nucleus, integrase performs the integration of the dsDNA into the host genome (By similarity).
What are the official names of this protein?
Transposon Ty2-LR2 Gag-Pol polyprotein, TY2A-TY2B, Transposon Ty2 TYA-TYB polyprotein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ENL11_ARATH
Sequence: MVSLISIVSVVFLLFTTFYHFGEARIINVGGSLDAWKVPESPNHSLNHWAESVRFQVGDALLFKYDSKIDSVLQVTKENYEKCNTQKPLEEHKDGYTTVKLDVSGPYYFISGAPSGNCAKGEKVTVVVQSPNHPKPGPAAVTPTLPPKPSTTPAAPAPAPPTPSPKSSTSTMAPAPAPAKSSAVGLVAGNGIFWASTLVAVIGLAFA
What is the function of this protein?
May act as a carbohydrate transporter (PubMed:24470637).  Required, together with ENODL11, ENODL12, ENODL13, ENODL14 and ENODL15, for male-female communication and pollen tube reception and burst at the synergid cell surface of the female gametophyte (PubMed:27524487).
What are the official names of this protein?
Early nodulin-like protein 11, AtENODL11, Phytocyanin-like protein ENODL11.
What is the protein family that this protein belongs to?
Belongs to the early nodulin-like (ENODL) family.
Protein: LEU3_CYBJA
Sequence: MPEKTIVVLPGDHVGTEITAEAIKVLKAIEEVKPEIKFNFQHHLIGGAAIDATGVPLPDDALEASKKADAVLLGAVGGPKWGTGAVRPEQGLLKIRKELNLYANLRPCNFASESLLDLSPIKAEVVKGTDFVVVRELVGGIYFGERKEDDGSGVASDTETYSVPEVQRITRMAAFMALQHNPPLPIWSLDKANVLASSRLWRKVVTETIEKEFPQLTVQHQLIDSAAMILIKYPTQLNGIVITSNMFGDIISDEASVIPGSLGLLPSASLASLPDSNKAFGLYEPCHGSAPDLPANKVNPIATILSAAMMLKLSLDLYEEGVAVETAVKQVLDAGIRTGDLKGTNSTTEVGDAVAEAVKKILA
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, IMDH, Beta-IPM dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEH_CHLAA
Sequence: MSSADWMAWIGRTEQVEDDICLAQAIAAAATLEPPSGAPTADSPLPPLWHWFYFLPRAPQSQLSSDGHPQRGGFIPPIPYPRRMFAGARIRFHHPLRIGQPARREGVIRNITQKSGRSGPLAFVTVGYQIYQHEMLCIEEEQDIVYREPGAPVPAPTPVELPPVHDAITRTVVPDPRLLFRFSALTFNAHRIHYDRPYAQHEEGYPGLVVHGPLVAVLLMELARHHTSRPIVGFSFRSQAPLFDLAPFRLLARPNGDRIDLEAQGPDGATALSATVELGG
What is the function of this protein?
Involved in the glyoxylate assimilation cycle used to regenerate acetyl-CoA and produce pyruvate as universal precursor for biosynthesis.  Catalyzes the hydration of 3-methylfumaryl-CoA (mesaconyl-C4-CoA) to (3S)-citramalyl-CoA.
What are the official names of this protein?
Mesaconyl-C(4)-CoA hydratase, 3-methylfumaryl-CoA hydratase.
What is the protein family that this protein belongs to?
Belongs to the HTD2 family.
Protein: STBC_STABI
Sequence: MPATRTPIHPEAAAYKNPRYQSGPLSVIPKSFVPYCELMRLELPHGNFLGYFPHLVGLLYGSSASPARLPANEVAFQAVLYIGWTFFMRGAGCAWNDVVDQDFDRKTTRCRVRPVARGAVSTTSANIFGFAMVALAFACISPLPAECQRLGLMTTVLSIIYPFCKRVTNFAQVILGMTLAINFILAAYGAGLPAIEAPYTVPTICVTTAITLLVVFYDVVYARQDTADDLKSGVKGMAVLFRNYVEILLTSITLVIAGLIATTGVLVDNGPYFFVFSVAGLLAALLAMIGGIRYRIFHTWNSYSGWFYALAIFNLLGGYLIEYLDQVPMLNKA
What is the function of this protein?
Prenyltransferase; part of the cluster that mediates the biosynthesis of LL-Z1272-beta, also known as ilicicolin B, a prenylated aryl-aldehyde produced by several fungi and that serves as a key pathway intermediate for many fungal meroterpenoids (PubMed:26972702).  The first step in the pathway is performed by the non-reducing polyketide synthase stbA that produces orsellinic acid by condensing acetyl-CoA with 3 malonyl-CoA units (PubMed:26972702).  The prenyltransferase stbC then prenylates orsenilic acid into grifolic acid (PubMed:26972702).  Finally, grifolic acid is reduced to ilicicolin B by the NRPS-like protein stbB (PubMed:26972702).
What are the official names of this protein?
Prenyltransferase stbC, Ilicicolin B biosynthesis cluster protein stbC, LL-Z1272-beta biosynthesis cluster protein stbC.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PCBP1_RABIT
Sequence: MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIITLTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSEKGMGCS
What is the function of this protein?
Single-stranded nucleic acid binding protein that binds preferentially to oligo dC (By similarity).  Together with PCBP2, required for erythropoiesis, possibly by regulating mRNA splicing (By similarity).
What are the official names of this protein?
Poly(rC)-binding protein 1, Alpha-CP1, Heterogeneous nuclear ribonucleoprotein E1, hnRNP E1.
Protein: KAD_HYPNA
Sequence: MNLILFGPPAAGKGTQAKRLVEQRGFVQLSTGDMLRAARASGSELGQRVAKIMDEGGLVSDEIVIALIEEQLTVQAGAPGFIFDGFPRTIGQAEALDSLLESRESKVDLVIRMIVDDTRLLERVTKRFEEQGRADDNPATFSRRLERYYEDTAPLVPMYAERGVLVEIDGMGSIEAVSAEIDAALKQSA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UXUA_LACP7
Sequence: MKMTFRWYGEGNDSITLKQIKQIPGCSGLMGVIDQYAAGEVWEESVIAEYVEHVHKAGLEVEVIESVNVHEDIKLGLPSRELYIENYIKTIRNLAKHGIKVIVYNFMPVLDWLRTDLARVIEEDGSNSLYYDEEELLGLTPLQIVENTSKSSNGFTLPGWEPERLKELENVLALYKNIDPDKLRENYKYFLEKVIPVCEECGVKMAVHPDDPAWPIFGLPRIAHSEELFDKILELYDSESHTICLCTGSLGSNPENNIPEIIRHFGGKNRVGCFHVRNVKYLGYRKFRESSHLSSDGSLDMFEIMKAIHETAPDTYIRPDHGRMIWDEVGRPGYGLYDRALGIAYLNGIWEALEKSSK
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: Y2140_MYCTU
Sequence: MTTSPDPYAALPKLPSFSLTSTSITDGQPLATPQVSGIMGAGGADASPQLRWSGFPSETRSFAVTVYDPDAPTLSGFWHWAVANLPANVTELPEGVGDGRELPGGALTLVNDAGMRRYVGAAPPPGHGVHRYYVAVHAVKVEKLDLPEDASPAYLGFNLFQHAIARAVIFGTYEQR
What are the official names of this protein?
UPF0098 protein Rv2140c.
What is the protein family that this protein belongs to?
Belongs to the UPF0098 family.
Protein: ENGB_HELPS
Sequence: MIAIKDAHFLTSSGQLSQCPASLTSEMVILGRSNVGKSSFINTLLGKNLAKSSATPGKTRLANFFSTTWEDKENALRATFNVIDLPGFGYAKVSKSLKKEWEGFLWELLSVRVSIKLFIHLVDARHLNLEIDKNAKENIQALLRPDQAYLSLFTKFDKLNKNEQHRLFLNAPKPFLINSAHFNALSSKYPTLEVVRQTLLKYLLTNPL
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: 3MGH_MYCBP
Sequence: MNAEELAIDPVAAAHRLLGATIAGRGVRAMVVEVEAYGGVPDGPWPDAAAHSYRGRNGRNDVMFGPPGRLYTYRSHGIHVCANVACGPDGTAAAVLLRAAAIEDGAELATSRRGQTVRAVALARGPGNLCAALGITMADNGIDLFDPSSPVRLRLNDTHRARSGPRVGVSQAADRPWRLWLTGRPEVSAYRRSSRAPARGASD
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: HSCB_PARXL
Sequence: MASLNDSHFDLFDLPAQFALDASALDHAYRTVQAQVHPDRFAAAGDAQKRIAMQWATRTNEAYQTLRDPLKRATYLLHLRGIDVGAENNTAMEPAFLMQQMEWRESIEDAAAAKNVDALDALLTELRDEERMRFDKLGALLDSGANQAAGEAVRQLMFIERVASEIGTQIERLEN
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: NDB4D_VAEMS
Sequence: MKTQFVILIVAVVLLQLISHSEAFLGALWNVAKSVFGKRGLRNFDDLDDTFEPEMSEADLKYLQDLLR
What is the function of this protein?
Cationic amphipathic peptide with antibacterial activities against both Gram-positive and Gram-negative bacteria (PubMed:22342498, PubMed:27912176, PubMed:31212183).  Also shows antifungal activities (PubMed:27912176).  Is mildly hemolytic against human erythrocytes (PubMed:22342498, PubMed:27912176, PubMed:31212183).  In addition, when tested in vitro on the parasite Trypanosoma cruzi (responsible of the Chagas disease), is able to reduce the number of the three forms (epimastigote, trypomastigote and amastigote) (PubMed:33004083).  Also shows antiplasmodial and cytotoxic activity (tested on Plasmodium gallinaceum, and MCF-7 breast cancer cell line) (PubMed:33442881).
What are the official names of this protein?
Amphipathic peptide VmCT1, CT1, Non-disulfide-bridged peptide 4.13, NDBP-4.13, Non-disulfide-bridged peptide 5.13, NDBP-5.13.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short antimicrobial peptide (group 4) family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a helical membrane channel in the prey.
Protein: BPIA1_RAT
Sequence: MFLVGSLVVLCGLLAQSTAQLAGLPLPLGQGLPLPLGQGLPLPLGQGLPLAVSPALPSNPTDLLAGNFANALSGGLLSGGLLGILENIPLLDVIKSGGGSSNGLVGGLLGKLTSSVPLLNNILDIKITDPRLLELGLVQSPDGHRLYATIPLSLKLQVNMPVVGSFLQLAVKLNITAEIVAMKDNQGRIHLVLGDCTHSPGSLQITLLNGVTPVQSSLDSLTGILTKVLPELIQGKVCPLINGILSGLDVTLVHNIAELLIHGIQFVIKV
What is the function of this protein?
Lipid-binding protein which shows high specificity for the surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC).  Plays a role in the innate immune responses of the upper airways.  Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P. aeruginosa and K. pneumoniae.  Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus.  Plays a role in the airway inflammatory response after exposure to irritants.  May attract macrophages and neutrophils.
What are the official names of this protein?
BPI fold-containing family A member 1, Palate lung and nasal epithelium clone protein.
What is the protein family that this protein belongs to?
Belongs to the BPI/LBP/Plunc superfamily. Plunc family.
Protein: URE2_OPITP
Sequence: MIPGEIIPAAGLPLDANTGLETKVLTVANTGDRPIQVGSHYHFFETNEALEFDRDATRGFRLNIPAGTAVRFEAGDTKRVELVALAGAREVYGLNARVNGKL
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_YERE8
Sequence: MLESLTLHPIALINGTVNLPGSKSVSNRALLLAALAEGTTQLNNLLDSDDIRHMLNALQALGVKYRLSADRTRCEVDGLGGKLVAEQPLELFLGNAGTAMRPLAAALCLGKNDIVLTGEPRMKERPIGHLVDALRQGGAQIDYLEQENYPPLRIRGGFRGGKLTVDGSVSSQFLTALLMTAPLAEQDTEIQIQGELVSKPYIDITLHLMKAFGVDVVHENYQIFHIKGGQTYRSPGIYLVEGDASSASYFLAAAAIKGGTVRVTGIGKQSVQGDTKFADVLEKMGAKISWGDDYIECSRGELQGIDMDMNHIPDAAMTIATTALFADGPTVIRNIYNWRVKETDRLSAMATELRKVGAEVEEGQDYIRVVPPAQLIAAEIGTYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARLSQIA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL2RA_RAT
Sequence: MEPHLLMLGFLSFTIVPGCWAELCLYDPPEVPNATFKALSYKNGTILNCECKRGFRRLNELVYMACLGNSWSNNCQCTSNSHDNSREQVTPQPEGQKEQQTTDTQKSTQSVYQENLAGHCREPPPWRHEDTKRIYHFVEGQIVLYTCIQGYKALQRGPAISICKTVCGEIRWTHPQLTCVDEKEHHQFLASEESQGSRNSFPESEASCPTPNTDFSQLTEATTTMETFVFTKEYQVAVASCIFLLLSILLLSGFTWQHRWRKSRRTI
What is the function of this protein?
Receptor for interleukin-2.  The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity.  TREGs suppress the activation and expansion of autoreactive T-cells.
What are the official names of this protein?
Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: MTNC_SHEB9
Sequence: MGIRAIVVDTAGTTTDLNFIQDVLFPYSVKALPDFLEQNQHNVLVENCICDTRDIALEPDADLARVTEILQQWVSEDRKATPLKTLQGLIWKQGYAHGEFKGHIFPDFIEAVKRFSEQNLRIYSFSSGSVDAQKLLFSHSDGGDLTEMFNGHFDTRTGNKLDKQAYCNILNTISLSPKQVLFVSDVIEELKAADAAGMMTCQMVRDSKQRTGEFRTISSFDELLIE
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: A1AT_PONAB
Sequence: MPSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHSEILEGLHFNLTEIPEAQVHEGFQELLRTLNQPDSQLQLTTGNGLFLNESLKLVDKFLEDVKKLYHSDAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTKEEDFHVDEVTTVKVPMMRRLGMFNIHYCEKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENENRRSASLHLPKLSITGTYDLKRVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFVGKVVNPTQK
What is the function of this protein?
Inhibitor of serine proteases.  Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin.  Inhibits trypsin, chymotrypsin and plasminogen activator (By similarity).
What are the official names of this protein?
Alpha-1-antitrypsin, Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Serpin A1.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.