PharMolix/UniProtQA huggingface dataset:
Protein: MIAB_HELPJ
Sequence: MKVYIETMGCAMNSRDSEHLLSELSKLDYKETSDPKMADLILINTCSVREKPERKLFSEIGQFAKIKKPNAKIGVCGCTASHMGADILKKAPSVSFVLGARNVSKISQVIHKEKAVEVAIDYDESAYAFEFFEKKAQIRSLLNISIGCDKKCAYCIVPHTRGKEISIPMDLILKEAEKLANNGTKELMLLGQNVNNYGVRFSSEHAKVGFSDLLDKLSEIQGIERIRFTSPHPLHMNDAFLERFAQNPKVCKSIHMPLQSGSSAVLKMMRRGYSKEWFLNRVERLKALVPEVGISTDIIVGFPNESDKDFEDTMEVLEKVRFDTLYSFIYSPRPFTEAGAWKERVPLEISSLRLERLQNRHKEILEEKAKLEVGKTHVVLVENRREMDGQIVGFEGRSDTGKFIEVTCKEKKNPGELVRVEIISHSKGRLMATTKGN
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_COXBR
Sequence: MKIFNSLTKQKEIFKPIESGKVKLYVCGMTVYDYMHIGHGRSWIIFDMVVRYLRMRGYEVTFVRNITDIDDKIIKRAGENKESPAALAERFIQILHEDEKALRVLSPDQEPRATQYVPEIIKLIQKLLDNQYAYTGQNGDVFFDVRRFKDYGKLSHRHLDKLQAGARVEVSDSKRDPLDFVLWKKAKPGEPKWDSPWGEGRPGWHIECSAMSSSILGQPFDIHGGGLDLKFPHHENEIAQSEAGEEKPFVKLWMHAGLLEINKEKMSKSLGNIISIREALKESDVEVLRYFLLSGHYRNPLSYSKENLENGRLALERFYLALRGLPVVNHEKTSSYTDRFYEAMDDDFNTPIAFALLFEMVREINRFRDNNQIEKAAVLAAELKCLGNIFGLLQYSPEQFLQGAKKEADVQEIKKLIDQRNEARAKKDWKTADQIRDQLTDLGVAIEDSSDGTSWRQE
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_FRAP2
Sequence: MSKYTILDKINTPSDLKLVPEGQLKELASELRTFLVDTLDVSGGHFASSLGATELTVALHYVFNTPYDNIVWDVGHQTYIHKILTGRKDKLITIKKDGGISGFPKRSESEYDTFGVGHSSTSISAALGMAIADRLQGKHSSSIAVIGDGAITGGMAFEALNHAGGIKEDILVILNDNEMSISDNVGGLSAHFSKIISGGFYNSIREKGKEVLKNIPPMFEFVKKIETQTKGMFVPANFFEDLGFYYVGPIDGHNVVELVKTLRILKDHKGPKLLHVITKKGKGYTKAESDPIKFHHVAPSFHSGDAQSKASKPTYSNIFGNWICQKAAKDKRLVGVTPAMKEGSDLIRFSQQYPNRYFDVAIAEQHAVTFAGGLACQGLKPVVAIYSTFLQRAYDQVIHDIALQDLDVLYAVDRAGLVGADGATHDGSFDISFMRCIPNHVIMTPSDENETYHMLELGYEYKGPAMVRYPRGAGIGAEITDNLDIKLGKAKLVKKGSRVAILNFGTLLPLANQLADKYHITVVDMRFVKPLDEQMINQICQNHNIVFTLEESSIAGGAGSAVNEYIFANDLSKNITVRNFGLKDEFLTHGTKDLLLDYSNLSFNKIAEVLEKLLSHKK
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: TRX2_EBVB9
Sequence: MDLKVVVSLSSRLYTDEIAKMQQRIGCILPLASTHGTQNVQGLGLGQVYSLETVPDYVSMYNYLSDCTLAVLDEVSVDSLILTKIVPGQTYAIKNKYQPFFQWHGTGSLSVMPPVFGREHATVKLESNDVDIVFPMVLPTPIAEEVLQKILLFNVYSRVVMQAPGNADMLDVHMHLGSVSYLGHHYELALPEVPGPLGLALLDNLSLYFCIMVTLLPRASMRLVRGLIRHEHHDLLNLFQEMVPDEIARIDLDDLSVADDLSRMRVMMTYLQSLASLFNLGPRLATAAYSQETLTATCWLR
What is the function of this protein?
Structural component of the T=16 icosahedral capsid.  The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes.  These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2.  Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.
What are the official names of this protein?
Triplex capsid protein 2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRX2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: P3F2A_XENLA
Sequence: MATTASNHYNLLGSGSSIVHADPGGMQQAQSYRDAQTLVQSDYTLQSNGHPLSHAHQWITALSHGDGAPWATSPLGQQDIKPTVQSSRDELHVSGTLQHQSRAPHLVHPAHGNHHGPGAWRSTGSTHLSSMASSNGQGLLYSQPSFTVNGMINPGSGQGIHHHGLRDSHDDHHGDHGHQQVSQAQQQHSQLQGGHQDHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSSGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAPEITSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGGTIPGAEDIYGASRDTPPHLGVQTSVQ
What is the function of this protein?
Transcription factor that may be implicated in patterning of the central nervous system during early development.
What are the official names of this protein?
POU domain, class 3, transcription factor 2-A, Transcription factor POU3-A, XlPOU3A.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CTAA_MACCJ
Sequence: MLKEKNLKWLSLFTTVLMLFVQIGGALVTKTGSADGCGSSWPLCHGKFVPTHIPKETLIELAHRGVSGLALLSVTWLVILSIKYIGHKKETKFLCYMSIGFIFAQALIGAAAVMWQQNGFVLALHFGISLISFSAVFLLTLLIFEVDQKFDATKLILQPKLRRHTIGLTSFIYFVIYSGALVRHEKASLACSSWPLCRKGAFILPQNFYEWVQMSHRTLAFILFIWLTYVAFHAMRNYAQYRVIKYGYMIAFILICLQVTTGALTIFTAVNLYIALLHALFITLLFGLLCYFILLISRAK
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ILL6_ORYSJ
Sequence: MEHGGHELAVVVLVLLLLVSATSCTFLEEDVILGTVEEAKVARLGGGGGGGSKGANASTRRADNTCAGVGVGVGGGGGGGGGGGGGGRGRFYLGWKEEIAGMAGRPETAAWLRAVRRRIHERPELAYEEVETSRLVRDELDAMGVGFRHPVARTGVVANIGTGRPPVVALRADMDALPIQEAVEWEHKSKNPGKMHACGHDAHVAMLLGAAKILKAREHHLRGTVRLLFQPAEESGAGAKRMIEGGALEDVEAIFAVHVSHQHPTSVIGSRTGPLLAGCGFFKAVIHGGRRSGDAVLAAASTIISLQSIVSREADPLDSQVVSVAMVNGSDHPAATARAAAAEEEEEFVLGGTFRAFSNASFYQVRRRIEEVITAQARVHGCEAAVDFFENQSFYPPTVNDARMYAHVKAVAGELLGAGSYRDVPPMMGAEDFSFYSQVVPAGFYYIGVRNETLGSVHTGHSPYFMIDEDVLPTGAAFHAAIAERYLANHSPSSSSSSDSDDPDVELEAS
What is the function of this protein?
Hydrolyzes certain amino acid conjugates of the plant growth regulator indole-3-acetic acid (IAA).
What are the official names of this protein?
IAA-amino acid hydrolase ILR1-like 6.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20 family.
Protein: KDSB_AERHH
Sequence: MSFVVVIPARYASTRLPGKPLADIHGKPMVQHVVEKALQSGADRVIVATDDERVQQALAACAGQAGFEVCMTSKDHQSGTERLAEVCRHYGFAADTIVVNVQGDEPLIPPVIIRQVADNLAAATAPMATLSVPIQDAEEVFNPNAVKVVTDQEGYALYFSRASIPWDRDRFAASREQIGDHYQRHIGIYAYRAGFIQRYVDWAPSALEQIEALEQLRVLWYGEKIHVAQALEAPPVGVDTQADLDKVRALLAN
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPYR_BOVIN
Sequence: MSGFSSEERAAPFTLEYRVFLKNEKGQYISPFHDIPIYADKEVFHMVVEVPRWSNAKMEIATKDPLNPIKQDVKKGKLRYVANLFPYKGYIWNYGAIPQTWEDPGHNDKHTGCCGDNDPIDVCEIGSKVCARGEIIRVKVLGILAMIDEGETDWKVIAINVEDPDAANYNDINDVKRLKPGYLEATVDWFRRYKVPDGKPENEFAFNAEFKDKNFAIDIIESTHDYWRALVTKKTDGKGISCMNTTVSESPFQCDPDAAKAIVDALPPPCESACTIPTDVDKWFHHQKN
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAND_ECOL5
Sequence: MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVNMPDEEARTWRPNVAYFEGDNEMKRTAKAIPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_WIGBR
Sequence: MNLTDNAVIFVKGGNGGKGCVSFRREKYIPKGGPDGGNGGNGGNVWIYSDKNTHDLYHCLVRKNFIAEDGENGKKNNSSGKNGKDVIIKVPIGTNIFFIKNSENIIFGHTRFHNQKFLVAKGGVRGLGNNYFKSPTNRTPMESTLGKLGESFKIKLDFVFLADVGLFGYSNTGRSCFMRSISNVKPKISFYPFTTLFPYIGSLNFLNKDIKFVDIPSFIEGKKKNNLRNRFLKHLQNCRLLLHFINLDVKNVKKTINKEKINIKILKSFRNLFLKPIWLIINKTDININSNIFFKQAQFVSNSLGYEKKFFFISLNDFISIKILINKILLFLEENKR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAOX_SCHPO
Sequence: MPAGTKEQIECPLKGVTLLNSPRYNKDTAFTPEERQKFEISSRLPPIVETLQQQVDRCYDQYKAIGDEPLQKNLYLSQLSVTNQTLFYALISQHLIEMIPIIYTPTEGDAIKQFSDIYRYPEGCYLDIDHNDLSYIKQQLSEFGKSDSVEYIIITDSEGILGIGDQGVGGVLISVAKGHLMTLCAGLDPNRFLPIVLDVGTNNETHRKNHQYMGLRKDRVRGEQYDSFLDNVIKAIREVFPEAFIHFEDFGLANAKRILDHYRPDIACFNDDIQGTGAVALAAIIGALHVTKSPLTEQRIMIFGAGTAGVGIANQIVAGMVTDGLSLDKARGNLFMIDRCGLLLERHAKIATDGQKPFLKKDSDFKEVPSGDINLESAIALVKPTILLGCSGQPGKFTEKAIREMSKHVERPIIFPISNPTTLMEAKPDQIDKWSDGKALIATGSPLPPLNRNGKKYVISQCNNALLYPALGVACVLSRCKLLSDGMLKAASDALATVPRSLFAADEALLPDLNNAREISRHIVFAVLKQAVSEGMSTVDLPKDDAKLKEWIIEREWNPEYKPFV
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: TXD15_MOUSE
Sequence: MQLLCWWQVLLWVLGLPAHGLEVAEDSGHPWREERPVPALQVGAVYLHEEEVAQDHRDQARAAEPMEASLGPRGDPMVVLSVVPGAAEDQRSPEAHDGTCSAQGEEDPSCGRENLFGLQGAGGFQDREEEYYAEPGVTEAEPVATEDANSTDSLKSPKVNCEERNVTGLENFTLKILNMSQDLMDFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPTLGFLALDASQHSSLSTRFGTVAVPNILLFQGAKPMARFNHTDRTLETLKIFIFNQTGIEAKKNVVVTQADQMGPLPSTLIKTVDWLLVFSLFFLISFIMYATIRTESIRWLIPGQEQEHAE
What is the function of this protein?
Acts as a positive regulator of ciliary hedgehog signaling (PubMed:29459677).  Required for cilia biogenesis (PubMed:29459677).
What are the official names of this protein?
Thioredoxin domain-containing protein 15.
What are the subcellular locations of this protein?
Cell projection, cilium membrane; Single-pass type I membrane protein.
Protein: TGB2_LSV
Sequence: MPLTPPPDYTRVYTALAIGASIAFFTGLITRNTLPSVGDLQHNLPHGGRYRDGTKSVEYCGPRKLNSVESGSRWTFQPWLLVIVLVALIIALGRQGHNCRACGRSH
What is the function of this protein?
Plays a role in viral cell-to-cell propagation, by facilitating genome transport to neighboring plant cells through plasmosdesmata,.
What are the official names of this protein?
Movement protein TGB2, 12 kDa protein, Triple gene block 2 protein, TGBp2.
What is the protein family that this protein belongs to?
Belongs to the Tymovirales TGBp2 protein family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane.
Protein: RS3A_EMENI
Sequence: MAVGKNKRLSKGKKGIKKRTVDPFTRKDEYSVKAPSTFANRDVGKTLVNRTSGLKNANDSLKGRIFEVSLADLQGDEDHAFRKVKLRVDEIQGKNCLTNFHGLDFTTDKLRSLVRKWQSLIEANVTVKTTDDYLLRLFAIAFTKRRPNQIKKTTYARSSQIRAIRKKMTEIMQREASSCSLAQLTSKLIPEVIGREIEKATQGIYPLQHVHIRKVKLLKSPKFDLGALLNLHGESTTDDKGQKVEREFKEQVLESV
What are the official names of this protein?
40S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2A6_AUSSU
Sequence: MYPAHLLVLLAVCVSLLGASDMPPQPLNLVQFSNMIQCANHGRRPTSNYMDYGCYCGKGGSGTPVDALDRCCKIHDDCYGEAEKSQNCAPYWTWYTWKCGSDGPQCDDSETGCKRIVCDCDVEAADCFAGAPYNNANWNIDTKKRCQ
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that inhibits collagen-induced platelet aggregation.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (By similarity).
What are the official names of this protein?
Acidic phospholipase A2 S3-24, svPLA2, ASPLA6, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BOLL_MACFA
Sequence: MQTDSLSPSPNPVSPVPLNNPTSAPRYGTVIPNRIFVGGIDFKTNESDLRKFFSQYGSVKEVKIVNDRAGVSKGYGFVTFETQEDAQKILQEAEKLNYKDKKLNIGPAIRKQQVGIPRSSIMPAAGTMYLTTSTGYPYTYHNGVAYFHTPEVTSVPPPWPSRSVCSSPVMVAQPIYQQPAYHYQATAQYLPGQWQWSVPQPPASSAPFLYLQPSEVIYQPVEIAQDGGCVPPPLSLMETSVPEPYSDHGVQATYHQVYAPSAISMPAPVMQPEPIKTVWSIHY
What is the function of this protein?
Probable RNA-binding protein, which may be required during spermatogenesis.  May act by binding to the 3'-UTR of mRNAs and regulating their translation (By similarity).
What are the official names of this protein?
Protein boule-like.
What is the protein family that this protein belongs to?
Belongs to the RRM DAZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_BURP0
Sequence: MAKISKRRQAFAAKVDRQKLYPIDDALALVKECASAKFDESIDVAVQLGIDAKKSDQVVRGSVVLPAGTGKSVRVAVFAQGEKAEQARAAGAEVVGMEDLAEQIKAGQMDFDIVIASPDTMRIVGTLGQILGPRGLMPNPKVGTVTPDVATAVKNAKAGQVQFRVDKAGIIHATIGRASFEPTALRTNLSALIEALQKAKPATSKGVYLRKIALSSTMGVGVRVDQGSLAAQ
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RBL_CUSOB
Sequence: MSPQTETKTSVGFKAGVKDYKLTYYTPDYETKATDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIERVFGEKDQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPAAYTKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKSQAETGEIKGHYLNATAGTCEEMLRRAYFAKELGVPIIMHDYLTGGFTANTSLAHFCRENGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRLSGGDHIHAGTVVGKLEGEREITLGFVDLLRDNFVEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTDIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGLDLAQDGNSIIRQASKWSPELAAACEVWKEIQFNFKSVDTLDLNEIK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid.
Protein: RR11_JASNU
Sequence: MAKGTRFINFRRYGRFGSRRYRRFGSHKSVRKIPRGVIHIQTSFHNTIVTVTDGRGQVVSWSSAGTCRFKGPRKRTPFAAQIVAADAIGPVVDQGLQRAKIKLKGTGRGRDAALRTISKSGIGFTSVQDVTPVPHNGCRPPNKKRQ
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CLTR1_PIG
Sequence: MDGVRNLTVSCASSNTCNDTIDDFRNQVYSTLYSMITVVGFFGNGFVLYVLIKTYHEKSAYQVYMINLAVADLLCVCTLPLRVVYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCIAIVFPVQNINLITHKKAKIVCIAIWIFVILTSSPFLMSTSYKDEKNNTKCFEPPQXNQAKYHVLVLHYVSLFVGFIIPFVIIIVCYTMIILTLLKNSMKKNISSRKKAIGMIIVVTAAFLISFMPYHIQRTIHLHFLHNDTKHCDSVLRMQKSVXITLSLAASNCCFDPLLYFFSGGNFREGLSTFRKHSLSTMTYVPKKKTSLPEKAQEIYKE
What is the function of this protein?
Receptor for cysteinyl leukotrienes mediating constriction of the microvascular smooth muscle during an inflammatory response.  This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (By similarity).
What are the official names of this protein?
Cysteinyl leukotriene receptor 1, CysLTR1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VM3E6_ECHOC
Sequence: VEDHCYYHGRVQNDAESTASISACNGLKGHFKLQGETYFIEPLKIPNSEAHAVYKYENIEKEDEAPKMCGVTQTNWESDEPIKKTLGLIVPPHGQKFEKKFIELIIVVDHSMVTKYNNDLTAVRTEIYERLNTVNEIYLPLNIHVALVGIVFWSNRDLINVTSSAADTLHSFGEWRGSDLLNQKRHDHAQLLTNVTLDGTTLGITFVFGMCKSDRSVELIRDYSNITFNMAYIMAHEMGHSLGMLHDTKSCTCGDKPCIMFSKESVPPPKEFSSCSYDQYNKYLLKYNPKCIVDPPLRKDIASPAVCGNGVWEEGEECDCGSPEDCENPCCDAATCKLKPGAECGNGECCDNCKIRKAGTECRPARDDCDVAEHCTGQSAECPRNEFQRNGQPCLNNSGYCYNGDCPIMLNQCIALFSPSATVAQDSCFQRNLQGSYYGHCRKEIGHYGKRFPCAAQDVKCGRLYCLDNSFKKNMRCKKDFSYSDENKGIVEPGTKCEDGKVCINRKCVDVNTAY
What is the function of this protein?
Snake venom zinc metalloproteinase that catalyzes the conversion of prothrombin (F2) to alpha-thrombin.
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like EoMP06, Prothrombin activator EoMP06, Snake venom metalloprotease, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CHED_CLOBM
Sequence: MDIKEIKVGIADLNVGKNPDKIITVGLGSCIGIALYDGIKCIGGLSHIMLPDSTQFSKVTNPMKFADLAIPILVEKMEKLGARKNGLKAKICGGASMFNFSDKSMVMDIGNRNGKAVKEKLKELSIPLLAEDIGGNKGRTMIFDTSTGKVYIKTVGLGTKEI
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: Y970_STAAN
Sequence: MNLIPRTSIVVYLKHMKHERQIRKYGHIVHSNRDRKFVIMYVNEQDVDQIVHKLMQLKYVRHIDGSPYKYLKKTYEKEKHEIYN
What are the official names of this protein?
UPF0298 protein SA0970.
What is the protein family that this protein belongs to?
Belongs to the UPF0298 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_COREF
Sequence: MNRFIDRVVLHLAAGDGGNGCVSVHREKFKPLGGPDGGNGGHGGDIILEVSPQVHTLLDFHYHPHVKAPRGANGAGDNRSGARGEDLILEVPAGTVVLNSKGETLADLTTVGMKFIAAAGGQGGLGNAALASRARKAPGFALNGEPGEQHDLILELKSMADVGLVGFPSAGKSSLISVMSAAKPKIGDYPFTTLQPNLGVVEVGHQTFIMADVPGLIPGASEGKGLGLDFLRHIERTSVLVHVVDTASMDPGRDPISDIEALEAELAAYQSALDEDTGLGDLDKRPRVVVLNKADVPEALELAEFLKGDIEQQFGWPVFIVSAVAQRGLDPLKYKLLEIVQQARKKRPKEKLAESVIIKPKPVDGRRRREEFEIRKDPDNPGGFLVVGEKPERWILQTDFENDEAVGYLADRLAKLGVEDKLRKAGAQTGSEVTIGGVTFEWEPMTSAVDTAASPRGTDIRLEKNERISAAERKRASQVRRGLIDEFDYGDGEEASRERWEG
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_CHRSD
Sequence: MTDFPPLVIDYHGSRLAGVDEVGRGPLVGAVVAAAVILDPARPIEGLADSKTLSEKRRLALADAIREQAAACAVAEASAEEIDALNIFHATHLAMRRAIDALPVTAEYLLVDGNRMPGHHVPGQCVVKGDRRHAAIGAASILAKVTRDAQMVALHERHPEYGFARHKGYPTREHLAALERLGPLEEHRRSFAPVKQWQLL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SWET3_ARATH
Sequence: MGDKLRLSIGILGNGASLLLYTAPIVTFSRVFKKKSTEEFSCFPYVMTLFNCLIYTWYGLPIVSHLWENLPLVTINGVGILLESIFIFIYFYYASPKEKIKVGVTFVPVIVGFGLTTAISALVFDDHRHRKSFVGSVGLVASISMYGSPLVVMKKVIETRSVEYMPFYLSFFSFLASSLWLAYGLLSHDLFLASPNMVATPLGILQLILYFKYKNKKDLAPTTMVITKRNDHDDKNKATLEFVVDVDRNSDTNEKNSNNASSI
What is the function of this protein?
Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.
What are the official names of this protein?
Bidirectional sugar transporter SWEET3, AtSWEET3, Protein SUGARS WILL EVENTUALLY BE EXPORTED TRANSPORTERS 3.
What is the protein family that this protein belongs to?
Belongs to the SWEET sugar transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MALQ_CHLTR
Sequence: MPSLSQSRRIIQQSSIRKIWNQIDTSPKHGVCVPLFSLYTQESCGIGEFLDLIPMIDWCISCGFQILQILPINDTGSCSSPYNSISSIALNPLHLSISALPYKEEVPAAETRIREMQQLSQLPQVHYEKVRSMKRDFFQEYYRVCKQKKLTDHPDFYAFCEQEKYWLHPYALFRSIREHLDNLPINHWPTTYTDLSQITEHERTFAEDIQFHSYLQYLCFQQMTQVREHANCKSCLIKGDIPILISKDSCDVWFYRHYFSSSESVGAPPDLYNAEGQNWHLPICNMKTLQQDNYLWWKERLRYAENFYSLYRLDHVVGLFRFWVWDESGCGRFEPHDPKNYLAQGQDILSHLLTSSSMLPIGEDLGTIPSDVKRMLESFAVCGTRIPRWERNWEGNGAYTPFDQYDPLSVTSLSTHDSSTLASWWKESPQESKLFAQFLGLPYSSTLSLHNHTEILKLSHKTSSIFRINLINDYLALFPDLISKTPRYERINLPGTISKNNWVYRVKPSIEDLSSHSKLNSLLEALF
What are the official names of this protein?
4-alpha-glucanotransferase, Amylomaltase, Disproportionating enzyme, D-enzyme.
What is the protein family that this protein belongs to?
Belongs to the disproportionating enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACNR_CORGL
Sequence: MSVAAGDKPTNSRQEILEGARRCFAEHGYEGATVRRLEEATGKSRGAIFHHFGDKENLFLALAREDAARMAEVVSENGLVEVMRGMLEDPERYDWMSVRLEISKQLRTDPVFRAKWIDHQSVLDEAVRVRLSRNVDKGQMRTDVPIEVLHTFLETVLDGFISRLATGASTEGLSEVLDLVEGTVRKRD
What is the function of this protein?
AcnR negatively controls the expression of the aconitase gene acn.  Binds to the imperfect inverted repeat in the acn promoter region.
What are the official names of this protein?
HTH-type transcriptional repressor AcnR, TetR-type regulator AcnR.
Protein: NPC1_YEAST
Sequence: MNVLWIIALVGQLMRLVQGTATCAMYGNCGKKSVFGNELPCPVPRSFEPPVLSDETSKLLVEVCGEEWKEVRYACCTKDQVVALRDNLQKAQPLISSCPACLKNFNNLFCHFTCAADQGRFVNITKVEKSKEDKDIVAELDVFMNSSWASEFYDSCKNIKFSATNGYAMDLIGGGAKNYSQFLKFLGDAKPMLGGSPFQINYKYDLANEEKEWQEFNDEVYACDDAQYKCACSDCQESCPHLKPLKDGVCKVGPLPCFSLSVLIFYTICALFAFMWYYLCKRKKNGAMIVDDDIVPESGSLDESETNVFESFNNETNFFNGKLANLFTKVGQFSVENPYKILITTVFSIFVFSFIIFQYATLETDPINLWVSKNSEKFKEKEYFDDNFGPFYRTEQIFVVNETGPVLSYETLHWWFDVENFITEELQSSENIGYQDLCFRPTEDSTCVIESFTQYFQGALPNKDSWKRELQECGKFPVNCLPTFQQPLKTNLLFSDDDILNAHAFVVTLLLTNHTQSANRWEERLEEYLLDLKVPEGLRISFNTEISLEKELNNNNDISTVAISYLMMFLYATWALRRKDGKTRLLLGISGLLIVLASIVCAAGFLTLFGLKSTLIIAEVIPFLILAIGIDNIFLITHEYDRNCEQKPEYSIDQKIISAIGRMSPSILMSLLCQTGCFLIAAFVTMPAVHNFAIYSTVSVIFNGVLQLTAYVSILSLYEKRSNYKQITGNEETKESFLKTFYFKMLTQKRLIIIIFSAWFFTSLVFLPEIQFGLDQTLAVPQDSYLVDYFKDVYSFLNVGPPVYMVVKNLDLTKRQNQQKICGKFTTCERDSLANVLEQERHRSTITEPLANWLDDYFMFLNPQNDQCCRLKKGTDEVCPPSFPSRRCETCFQQGSWNYNMSGFPEGKDFMEYLSIWINAPSDPCPLGGRAPYSTALVYNETSVSASVFRTAHHPLRSQKDFIQAYSDGVRISSSFPELDMFAYSPFYIFFVQYQTLGPLTLKLIGSAIILIFFISSVFLQNIRSSFLLALVVTMIIVDIGALMALLGISLNAVSLVNLIICVGLGVEFCVHIVRSFTVVPSETKKDANSRVLYSLNTIGESVIKGITLTKFIGVCVLAFAQSKIFDVFYFRMWFTLIIVAALHALLFLPALLSLFGGESYRDDSIEAED
What is the function of this protein?
Involved in sphingolipid trafficking.  May recycle sphingolipids between cellular membranous compartments.
What are the official names of this protein?
NPC intracellular sterol transporter 1-related protein 1, Niemann-Pick type C-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the patched family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.