PharMolix/UniProtQA huggingface dataset:
Protein: CRYAA_CANLF
Sequence: MDIAIQHPWFKRALGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVLEDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPKVPSGVDAGHSERAIPVSREEKPSSAPSS
What is the function of this protein?
Contributes to the transparency and refractive index of the lens.  Acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions.  Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
What are the official names of this protein?
Alpha-crystallin A chain.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Protein: THII_STAAC
Sequence: MKYDHLLVRYGELTLKGSNRKKFVNQLRNNVNKSLKGLDGFVVKGKRDRMYIELEDHADINEITYRLSKIFGIKSISPVLKVEKTIEAISAAAIKFAQQFEENSTFKIDVKRADKNFPMDTYELQRELGGAVLKHFDNISVNVKRPDHEIRVEVRLDAIYMYEEVVPGSGGLPVGTGGKTLLMLSGGIDSPVAGMEVMRRGVTIEAIHFHSPPFTSDQAKEKVIELTRILAERVGPIKLHIVPFTELQKQVNKVVHPRYTMTSTRRMMMRVADKLVHQIGALAIVNGENLGQVASQTLHSMYAINNVTSTPVLRPLLTYDKEEIIIKSKEIGTFETSIQPFEDCCTIFTPKNPVTEPNFDKVVQYESVFDFEEMINRAVENIETLEITSDYKTIKEQQTNQLINDFL
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_LEGPH
Sequence: MAKELTLSIIKPDAVAKSVIGEIYTRFEKAGLDIVAAKMTQLSREQAESFYDIHRARPFFKDLVDFMISGPVMIQVLKGENAVAKNREIMGATNPKEAAPGTIRADFADSIDANAVHGSDSLENAAREIAFFFEQHELCNR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSPE_DICDI
Sequence: MTFVDNFEFNQNTPRLVRGPFIILNSIIFSLSFILLCSTGIIIYYLNEYYLVKDLTIPLGSFILSAYMVITTIVGGIAIWKKKLGLHLTFMVFLVVLIVCLVGVSAKMIVDSGNPEKLQHKIENIWYKVGNYQHHSKHYHHGIIEIIEKHHRCCGWSKEIEGNYCVHFNRRESGHGYCAPYVEKSVESILKYLGYYGIVLSVIELILLILSGFFLLKTNKNVKSKSFILQD
What are the official names of this protein?
Probable tetraspanin tspE.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TUSD_YERP3
Sequence: MSALKYCLLVTGPAYGTQQASSAYQFAQAVVGAGHHLVSIFFYREGVLNANQLTAPASDEFDLVRAWQQLAAEQAVTLNVCVAAALRRGITDQHEAEQLNLAAANLQPGFTLSGLGALAEATLTCDRMVQF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Accepts sulfur from TusA and transfers it in turn to TusE.
What are the official names of this protein?
Sulfurtransferase TusD, tRNA 2-thiouridine synthesizing protein D.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_PROMP
Sequence: MGSSFGKNFRVTTFGESHGGAVGVILDGCPPKLKINIDLIQNELDRRRPGQSKITTPRNEDDKLEILSGLKEGITLGTPIAMMVRNKDQRPGDYSNLEQVFRPSHADGTYHLKYGIQAGSGGGRASARETIGRVAAGAIAKQLLKNLFNTEILSWVKRIHDIDSQVNKNKLTLSKIDSNIVRCPDDKVAAKMIKRIKELQQDGDSCGGVIECLVKNVPSGLGMPVFDKLEADLAKALMSLPATKGFEIGSGFLGTYLRGSEHNDSFIESDDISKLKTISNNSGGIQGGISNGENIEMKIAFKPTATIGKEQKTVNADGKEVLMKAKGRHDPCVLPRAVPMVDSMVALVLADHLLLHQAQCSIIK
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: SECE_RICRI
Sequence: MFKEYKIYKFFEQVKQETYKVVWPTRKELVASTLVVVVAVFIFSLTCLVLDYSIHNIMQLLLNIGK
What is the function of this protein?
Essential subunit of the Sec protein translocation channel SecYEG.  Clamps together the 2 halves of SecY.  May contact the channel plug during translocation.
What are the official names of this protein?
Protein translocase subunit SecE.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SYR_PYRAB
Sequence: MLSRVKEGAREKIIKVIESLAPGWKGEIEFKDTPSPELGDFGTPVAFKLARVMKKPPFQIAELIVEELKKELPEGIREVRAINGYVNFFVDYGYLARQLIVEVLEKGDRFGSSDIGRGKKVIVEHTSVNPTKPLHMGHARNAILGDSMARILRFLGYEVEVQNYIDDLGIQFAQVYWGYLKLREKFEKIMKELKEKGIKEDPIDHVLGLLYVEVNRVLEENPEIEAEIRDIMKKLESGELNGRELAESVVRAQMVTTYRLGIKYDLLVWESDIVSRKLFEIAVKLLERNENFYTPNEGKYKGAFVMDLSKLFPDMKNPYLVLRRSDGTATYTGKDIAYHLWKFGKIDVDLLYKPWDEHTWTTAPDGESVKGKFGGADIVINVIGAEQRHPQMAIKHALKLLGFEDAAENLHHLAYEHVERPEGKFSGRKGTWVGFTVDEVINEAIKRARELIEEKSPGLSDEEKEEIAEKVGVGAIRYNMVKYSPDKKIIFRWEDVLNFEGESAPYIQYAHARCSSILRKAGNPEWEALLKEANFKELTERERELIILLSKFPEVVEQAGRDVKPHLIAWYANELASLFNKFYMDHPVIKAEKGIREARLLLVMAVRQVLRNSLWLLGIEAPDRM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPX_HALHL
Sequence: MLTRIALLLATNIAVVLVLSIILNLLGVEQFLREQGIDAEMVTLLIFAAGIGFAGSFISLAMSKYMAMKMMGAKPIESPRGEQEQWLVETVRRFAQREGIGMPDVAIYDAPEINAFATGARRNSALVAVSSGLLQNMTRDEAEAVIAHEVAHVSNGDMVTLTLIQGVVNTFVIFLSHVAGRFVDRVVFKNEGGHGPGFWITMIFAQMVLGVLASMITMYFSRKREFRADSGAAKLAGRDKMIAALEKLKRSVEPQNMPDEMEAFGINGRMGGSSIKRLFMSHPPLDERIEALKGRPV
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DCD_CUPPJ
Sequence: MSIKSDKWIRRMAEQHGMIEPFEPGQVREADGRKIVSYGTSSYGYDIRCADEFKIFTNINSTIVDPKNFDEKSFVDFKGDVCIIPPNSFALARTMEYFRIPRSVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYAGEGCAQVLFFESDEVCETSYADRGGKYQGQHGVTLPKA
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: GLYA_STAAS
Sequence: MSYITKQDKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGGCEFVDVTESIAIDRAKALFGAEHVNVQPHSGSQANMAVYLVALEMGDTVLGMNLSHGGHLTHGAPVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASAYSRTIDFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRGGMILCKEEYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEALENNFKTYQQQVVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDSVGITCNKNTIPFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAKIISLALKNSKDEEKLQQAKERVAKLTAEYPLYQ
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSP_BRASB
Sequence: MTTPLKPLDDAATSFARRHIGPSPRDVAAMLETVGAKSVAELMAQTLPGTIRQATPLTLEPALSEVEAIGHMRALAAQNQVFTSLIGQGYSGTIMPAVIQRNILENPAWYTAYTPYQPEISQGRLEALFNFQTMICDLTGLDVANASLLDEGTAAAEAMALAERSARAKTKAFFVDRNVHPQTLAVLRTRAEPLGWQLIVGDPVKDLDGAEVFGGLLQYPETTGALRDPRADIAKLHDKGALAILAADLLALTVIASPGELGADIAIGSAQRFGVPMGYGGPHAAYMAVRDALKRSLPGRIVGLSVDSRGAPAYRLALQTREQHIRREKATSNICTAQVLLAVIAAMYAVYHGPDGLKSIARTVHRRAAVLAAGLRKLGFAPASDSFFDTVLVEAGANCDEIIARAESQRINLGRDGSRLRIALDETTTADVVEAVWRAFGGELSYAAIEAEARDAVPAELKRQRPFLTHPVFHAHRSETEMLRYLRKLADRDLALDRAMIPLGSCTMKLNATTEMIPLTWPEFSSLHPFVPRAQAAGYHTMFADLQDWLCRISGYDAVSLQPNSGAQGEYAGLLAIRGYHAARGEGHRTICLIPSSAHGTNPASAHMVGMEVVVVGCDSNGNVDLADLKAKAELHSAKLAAIMITYPSTHGVFEEHIRDICDIVHAHGGQVYLDGANLNAQVGLSRPGDYGADVSHFNLHKTFCIPHGGGGPGMGPIGVKAHLAPFLPGHPATDAATPSPVGPVSAAPYGSASILTISYIYMLLMGGEGLTRATEIAILNANYVAARLDPHFPVLYRNERGRVAHECIIDPRPLKQTCGVTVDDIAKRLIDYGFHAPTMSFPVAGTLMIEPTESESKAELDRFCDAMIAIRKEIAAVEQGRFTIEASPLRHAPHTVHDIADDDWNRVYRRSEGCFPEGTSRTDKYWCPVGRVDNVYGDRNLVCSCPPIGDYAQAAE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: Y946_GEOSW
Sequence: MPKIGVEHSLTSVQEALKAKGYEVIPLRGENDAKGCDCCVITGQDANVMGIQNTVTAGSVIEASGLTAEEICQKVEEKLR
What are the official names of this protein?
UPF0180 protein GWCH70_0946.
What is the protein family that this protein belongs to?
Belongs to the UPF0180 family.
Protein: RL22_THESQ
Sequence: MKLQVPRSSLKRSIFHKKRKELLSSLPKIEAKAVARYIRISPRKARAIANTIRGKSVEEAFQILAFSPKKAARIMEKVLKSAVANAENNFGLSVENLYVSECYVNDGPRMKRIWPRGRGRADIIQKRMSHITVVVRDRSKEDEYRKALEELEKKISSEE
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: GPMA_CHLAB
Sequence: MAFLILLRHGKSVWNEKNLFTGWVDIPLSQKGIDEAMLAGEAIKDLPIDCIFTSSLVRSLMTALLAMTHHNSKKIPYIVHDDPEQKHMSKIYSDEVNHMIPLYRSSALNERMYGELQGKNKKKTAEQFGEEQVKLWRRSYKTAPPNGESLYDTGQRTIPYFQETIFPLLQNSKNVFVSAHGNSLRSLIMDIEKLSEEEVHSLELPTGKPIVYLWTGHTFERHPELFG
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: PSBN_PROM3
Sequence: MENSSSETYSLLIAMVTITFGLTGYGLYTAFGPPSKELEDPFEEHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: CYB_PONAB
Sequence: MTSTRKTNPLMKLINHSLIDLPTPSNISAWWNFGSLLGACLIIQITTGLFLAMHYSPDASTAFSSIAHITRDVNYGWMIRHLHANGASMFFICLFLHIGRGLYYGSFTHLETWNIGIILLFTTMMTAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWVWGGYSVNSPTLTRFFTLHFMLPFIITALTTLHLLFLHETGSNNPLGIPSHSDKITFHPYYTIKDILGLLLFLLALMTLTLLSPDLLSDPDNYTLANPLSTPPHIKPEWYFLFAYAILRSVPNKLGGVMALMLSILILTTIPALHMSKQQSMTFRPLSQFLYWLLIADLLILTWIGGQPVSYPFITISQVASTLYFTTILLLMPASSLIENHMLKWT
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: BMT9_CANAL
Sequence: MEKLIQSTISLFISLSLKISTKSYKSIISILFIISLLSIILTTTITVYHDPERIITTTTTTTSASKSVFTASSPKQQDKLQQEIDQHQSDNSHEQQGKRIIIFPNNFPLIKNDQLVKYYIDTMNQALQPHDLIYRNCFEYKIPQLSYSSQKIDVFSDGGGGDQSGIKCRKLSSQVNVKVSPAINKNGNMRQILTRFMQDDGLYFQEFLPFFPNLKEQLQSADDDIINKHWYQFIGSTVWLQQYGVHLMISRIIYTEVDQGLPIISLAYLQLFDRNWNELNDVELIIPDYETTTTTTTQSKYKYKSIIYPYFAPIPIYHNVKQLNTGKFFGVEDPRIMLITNEFGFEEPIIIYNSHHRKISNIDYENGGDNQGKINFKNYRSLFIGWLWKTQIGKFNLEQLPSEHTLDNHKANKNDANNNDYSKNEYIKIKELTRPNNQRNLLEKNWSLFLNHQEKLNHGYHSFIYFIYQFKDLKILKCPLSSSTTKKNNDGDDRFDSGCQWEYQINDDDNFGSGYLHGGTELINVNELLDNYLSKSSTSTSINGKQLTNSIKDRLPLNRQIWIGFARAAMRHCGCSETMYRPNMVILVKDDVPTNTNIASGKSNYRLTHVSSFMDLGIEVLPWWEDKGLCEGKNVVIPNGISSWTIENESNNLESESSTITSNNLVDYLTITITRRDTTIDLVYIKGLLNALLLNPDNNNSNNDVDDTEEGSSIFKSSVLFNVDLVKDYSSTTTTTTTKNVNKNLDCALQYSHKYCQIYGEKLKIEDEFNNKGKDKGKDKSN
What is the function of this protein?
Beta-mannosyltransferase involved in cell wall biosynthesis through beta-1,2-mannosylation of cell wall phosphopeptidomannan.
What are the official names of this protein?
Beta-mannosyltransferase 9, WRY family protein 5.
What is the protein family that this protein belongs to?
Belongs to the BMT family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: LGT_CLOB1
Sequence: MNPIAFHVGNLAIRWYGVIISMGTALGLLLAMYNCKIREASYDEFINMFLIAFPSAIIGARLYYVIFEFEDYRDNLINIFNTRQGGLAIHGGIIFGVLAVYIYLKYRKESFFEYVDVAAPSIILGQAIGRWGNFFNSEAHGGPVTKEFISKFPQFIQNGMFIEGTYYHPTFLYESIWNFIICIFLVYLLKKTKKKGIVFMAYIGLYSLGRFFIEGLRTDSLYLGSIRVAQLISVLGIILSIFFIYNIIKKEKRY
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DEF_ESCF3
Sequence: MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVEKLDRLKARA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: RSMC_SHEB9
Sequence: MLTNPSQVIIRNQDSLSQHKVLVLNHEADLLPKALLDVAASVDALALDYHHYLHLAPHANSKLRCYFGHDLPHQDPLEREKYDTVIVYFPKAKPLAPYLFNLAANHLVPNGQLLVVGENKGGIKSLVKLLPEYFATGMKLDNARHCLLFGSSLEGSAPAMKLSDWVSQYQLSTPQGEISICNLVGVFSEKRLDLGTELLLSHLPTLSGRVLDFGCGAGVIAAALLKAQPSLSLECVDINAMALASCELTLAANGMTAKVYPSDGLAQTTGKFNGIISNPPFHDGLASTTSIAQNFVTDSAKQLQHNGIWQIVANRHLPYSDIIAAEFGQLKVVADNNKYKLYYFQHK
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZYM1_SCHPO
Sequence: MEHTTQCKSKQGKPCDCQSKCGCQDCKESCGCKSSAVDNCKCSSCKCASK
What is the function of this protein?
Metallothionein involved in tolerance to zinc and cadmium.  Binds four zinc ions.
What are the official names of this protein?
Metallothionein zym1.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y043_SFAVA
Sequence: MSHTERIGQTPKAYVLANERGPFSVEVYLNPGTSNTYQYVATTRSKFNATDYDDLPWNYTSGKKVITANGVVSGGDRYVFALRSEIPQDIQVTMYNVNNGVSSNMNVRQPSDNSYYQPPPPPPPPRLVYNNGELYDNMINDTGYATELGKKLNDNFKKLWDYVNQPIVWLGVSALVGYLIYRYYYMSRPIGFGNSGAYDVPLLDTPLLRDSYRLPQSFTRDPIFRNSI
What are the official names of this protein?
Uncharacterized protein ORF43.
What is the protein family that this protein belongs to?
Belongs to the ascovirus HvAv ORF58 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ZERSY_ZINZE
Sequence: MRLEGKVALVTGGASGIGESIARLFIEHGAKICIVDVQDELGQQVSQRLGGDPHACYFHCDVTVEDDVRRAVDFTAEKYGTIDIMVNNAGITGDKVIDIRDADFNEFKKVFDINVNGVFLGMKHAARIMIPKMKGSIVSLASVSSVIAGAGPHGYTGAKHAVVGLTKSVAAELGRHGIRVNCVSPYAVPTRLSMPYLPESEMQEDALRGFLTFVRSNANLKGVDLMPNDVAEAVLYLATEESKYVSGLNLVIDGGFSIANHTLQVFE
What is the function of this protein?
Catalyzes 8-hydroxy-alpha-humulene into zerumbone in presence of NAD.  Also converts borneol to camphor in vitro.  Zerumbone is a highly promising multi-anticancer agent.
What are the official names of this protein?
Zerumbone synthase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: DOXA_STRPE
Sequence: MAVDPFACPMMTMQRKPEVHDAFREAGPVVEVNAPAGGPAWVITDDALAREVLADPRFVKDPDLAPAAWRGVDDGLDIPVPELRPFTLIAVDGEAHRRLRRIHAPAFNPRRLAERTDRIAAIAGRLLTELADASGRSGKPAELIGGFAYHFPLLVICELLGVPVTDPAMAREAVSVLKALGLGGPQSGGGDGTDPAGGVPDTSALESLLLEAVHSARRNDTPTMTRVLYERAQAEFGSVSDDQLVYMITGLIFAGHDTTGSFLGFLLAEVLAGRLAADADEDAVSRFVEEALRYHPPVPYTLWRFAATEVTIGGVRLPRGAPVLVDIEGTNTDGRHHDAPHAFHPDRPSWRRLTFGDGPHYCIGEQLAQLESRTMIGVLRSRFPEARLAVPYDELRWCRKGAQTARLTELPVWLR
What is the function of this protein?
Involved in the biosynthesis of the anthracyclines carminomycin and daunorubicin (daunomycin) which are aromatic polyketide antibiotics that exhibit high cytotoxicity and are widely applied in the chemotherapy of a variety of cancers.  In vivo, DoxA catalyzes the C-13 hydroxylation of 13-deoxycarminomycin and 13-deoxydaunorubicin to yield 13-dihydrocarminomycin and 13-dihydrodaunorubicin, respectively, as well as the oxidation of these 13-dihydro-anthracyclines to their respective 13-keto forms, carminomycin and daunorubicin.  In vitro, it also catalyzes the C-14 hydroxylation of daunorubicin to form doxorubicin (adriamycin), although this strain is not a doxorubicin producer.  It can only use NADP.  DoxA acts jointly with DnrV.
What are the official names of this protein?
Cytochrome P-450 monooxygenase DoxA, 13-deoxycarminomycin C-13 hydroxylase, 13-deoxydaunorubicin C-13 hydroxylase, 13-dihydrocarminomycin C-13 hydroxylase, 13-dihydrodaunorubicin C-13 hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_RALSO
Sequence: MQFPESWLRSFVNPPIATAELSHRLTMAGLEVEEVDPVAPPFSQIVVGHVVEVNKHPDADRLNVCKVDAGTGELLQIVCGAPNVSVGIKVPCALVGAELPPGDDGKPFKIKIGKLRGVESYGMLCSARELKLSEEHGGLLILPEDTPVGADIRKVLDLDDQIFIIKLTPNKADCLSIHGVAREVSALTGAPITLPTMAPVAVTLSDKLPVKVEAPDLCGRFAGRIIRGVNARAKTPAWMVSRIERAGMRSVSALVDISNYVMLELGRPSHVFDLDKIHGGLTVRWGKPGEQLKLLNGDTVTVDDKVGVISDEQAIESLAGIMGGDKTAVTLDTQNIYVEAAFWWPAAIQGRARRYNFSTDAGHRFERGVDYATIVEHIERISALILDICGGQAGPIDDQIVNCPKREPVRMRVARAARVLGIPLSHEVVSDVFKRLGLTFSVDGDVFVVEPPSYRFDIEIEEDLIEEVARIYGFEQIPAKPPVAENAMRPTNEARRTMHDVRHAVAARDYHEVVNFAFVETEWEADFAGNTQPIPLLNPIASQYSVMRSTLIGGLLDKVRYNLNRKASRVRLFEVGRVFRRDAEVADGGLSVAGYAQPMRVGGIAYGPAAEEQWGVPARAVDFFDVKGDVESLLWPLQARFERAEHSALHPGRAARVVLDGRAVGWIGELHPRWLQKYELPTAPVVWELDLDAITAVGLPAYREVPRVPAVTRDIALVVRQDVGVQDLVDAFEKAAAGMPWQRYLQGVVLFDEFRPKAATAAIGAQEKSLAFRITLQDTDSTLQDDLVEAATQQLIRAAGDAFGARLRA
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMJ_RHOPT
Sequence: MAETARTAPAVDFVGGAVGYRFRTQAGRSHALLKATGLSPTRSLHVIDATAGLGRDAFLLASMGATVTLIERVPEVHALLADALEAARAESDELAAIIGRMTLLHGDARVLLPTLQADVITIDPMHPPRTKTALVKQEMRLLRDLVGADPDVGELLAAALSADCGRVVLKWPLRAAAPPASRKPSHQIAGKTVRYDVYVRPRAT
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMC_CERS1
Sequence: MRFTRLRLNGFKSFVDPTDLVIHEGLTGVVGPNGCGKSNLLEALRWVMGENRPTAMRGAGMEDVIFAGAATRPARNFAEVALVLDNADRLAPAGFNDADTIEIVRRITRDAGSAYKANTKDVRARDIQMLFADASTGAHSPALVRQGQISELINAKPKARRRILEEAAGISGLYQRRHEAELRLAATEQNLARVEDVLDQLAQQLSTLARQAKQAARYREIGEELRRAEGSLLYRRWREADLARTEALAILRERMTAAGQAEAAARKAAGARAEAEATLPPKREEEAIAGAVLQRLTVERDTLAAEEDRARATIATLVSRVDQLGRDIEREAGLNRDAAETIGRLEWEREALETAHEGHEERLAEAAEAAREAGAALGEREEILSERTEDAARLSARHQSAQRMLVDSRTTLARSEAEAARARETVEAAAEAQERAAETWEEAAAAQEEAQERAEAAEEALVQADEARAEAQSREAEARAQRSAAEGEANALRAEVAALARLVDREAQAGSQLLDRIQVEPGFEAALGAALSDDLRAPEVAADAPSGWAALPDYDETAPLPAGAEPLAPHVGVPEVLRRRIGQIGLVGREAGAALQPLLQPGQRLVSIEGDLWRWDGFRAGAEDAPSAAALRLKQLNRLVALKRDLEEVAARAEGARQAHEALQARLAQLTRADQEAREARRAADARVTEASRAAARAEADRSISGGKLESARLAVKRYEDEAMEARARLREAEGVASALPDLEAARAGLEDLKMAVEAARIAMMSRRSLHDELRREGEARVKRRQEVTKDLSGWKHRLETAEKRSAELAERKAETEEALREAAEAPEEIAARREELAEAIEAAEERRARASDALASAEAALRAAQEAEREAERQAGESREARARAEARADAATEALQLAAERIREETERTPQQLLEALAVDPERIPTVEALETDVGRLKRQREALGAVNLRAEEDAQAVQTEHDTLKAEKTDLEEAVKKLRAGIQGLNREGRERLLTAFEQVNASFGTLFTHLFGGGEARLVMVESDDPLEAGLEIMCQPPGKKLSTLSLLSGGEQTLTALALIFAVFLANPAPICVLDEVDAPLDDANVTRFCDLLDEMTRRTETRFLIITHHAVTMARMDRLFGVTMAEQGVSQLVSVDLKRAEALVA
What is the function of this protein?
Required for chromosome condensation and partitioning.
What are the official names of this protein?
Chromosome partition protein Smc.
What is the protein family that this protein belongs to?
Belongs to the SMC family.
What are the subcellular locations of this protein?
Cytoplasm.