PharMolix/UniProtQA huggingface dataset:
Protein: CTAA_GLUDA
Sequence: MSAHMSLRPAGSRDDASPIALRDRRRISTWLFVICFMLIGQIALGGYTRLTGSGLSIMDWRPVTGIIPPLSHTEWERQFALYQTIPQYKILHDGFGLAGFQKIFWAEWTHRFWARVMSLALLAPLVWFAVTGALTRGLIARLLLYFVLGGLQGAIGWFMVASGFDQNSTAVEPVRLVLHLGCAFALYIAILWTALSVRTPRAAFIPATAAVVRTKRLVWCATILIGITITAGGFTAGTHAGFSYNTFPLMDGRLIPHGYARLSPFWLNWFENVPAVQFDHRLLATVTALAIGACLFAGLRTPQLGKPAQDALMLMGWAVLIQYALGITTLLLVVPAWAGTVHQTWAAVLLTIAIVTLHRLRGVGRV
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DNAK_BUCBP
Sequence: MSKIIGIDLGTTNSCIAIMDGNKARVLENSEGDRTTPSIIAYTNDNEILIGKPAKRQSITNPKNTLFAIKRLIGRKFTDNEVQRDIKIMPYKIIQSENGDAWINIKNKKLAPPQISAEILKKMKKTAEDYLGESIQEAVITVPAYFNDAQRQATKDAGRIAGLKVKRIINEPTAAALAYGLDKGKGNKTIAVYDLGGGTFDISIIEIDDVDKEKTFEVLATNGDTHLGGEDFDNRLINYLVEDFKKDQGTDLRNDSLAMQRLKESAEKAKIELSSTQQTDVNLPYITADSTGPKHLNIKVTRSKLESLVEDLITRSIEPLKIALKDAKLSISDIDDVILVGGQTRMPMVQKKVAEFFKKEPRKDVNPDEAVAVGAAVQGGVLSGEVKDVLLLDVTPLSLGIETMGGVMTTLISKNTTIPTKHSQIFSTAEDNQTAVTIHVLQGERKRSIDNKSLGQFNLDGIQPAPRGMAQIEVTFDIDSDGILHVSAKDKNTGKEQKITIKASSGLNETEIKKMILDAEQNSESDQKFEELVKVRNQGDQISHSTKKQLKDLEKTINVNDQKEINEALNKLDTALKGENKTKIEEKIQEVLKISTKLIEKNKPKQTSESSNSNSPSSSKPEENVVDAEFEEVKDQKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: KAD_STRLI
Sequence: MRIVLVGPPGAGKGTQATRLAETLHIPHISTGDLFRANISQQTELGKLAKSYMDAGNLVPDEVTIAMDRTAWSSPTPRAFLLDGFPRNVSQAEALDELLETEDMKLDAVLDLEAPEDEVVKRIAGRRVCRNDSAHVFHVTYTPPKKEGVCDVCGGELYQRDDDSEETVRKRLEVYHTQTEPIIDYYKSQGLVATIAATGP
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTXA_HETP5
Sequence: MAGKDWEIVQEKAFTAWVNSVLDKRGEKISDVAKDLSDGVKLIFFLELISGKKFNKKFDYEPKARINMIQNLALALHFLEDELKIKVQGIGAEDFVDNNKKMILGFLWTLYRKYRIAVISEGDKSSEEGLLLWCKNTTTGYNGVNVTSFTKTFRDGLAYLALAHKFDQSQFNFADYEKLDPIARLNAAFEYAEKGLGVPKLLEAEEVMRGTTDERSLVLYTSLFFHAYRAKEEKERLEASKSDLASKLAGLQNSLESEKLSREQLIKQKDELKSLLASLEGEAAEREKFLRELEAKLEEILKNLELERLARMELESRLSKMEKDKAILELKLAEAQDEKARLEAQIEADRIRSAAEAQSLGLLRKHLDQHVQDLIKWQKLSIENSSSTFDDQIIEEVSGLPFGEQVKHLATKLEDENKAIQKLLLSKEDDLKTAKKKAGK
What is the function of this protein?
Actin-bundling protein.  When linked to F-actin the actin filaments form preferentially anti-parallel bundles that associate into meshworks.  Plays a major role in cytokinesis (By similarity).
What are the official names of this protein?
Cortexillin-1, Cortexillin I.
What is the protein family that this protein belongs to?
Belongs to the cortexillin family.
Protein: GLGS_ECO45
Sequence: MDHSLNSLNNFDFLARSFARMHAEGRPVDILAVTGNMDEEHRTWFCARYAWYCQQMMQTRELELEH
What is the function of this protein?
Major determinant of cell surface composition.  Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides.
What are the official names of this protein?
Surface composition regulator.
What is the protein family that this protein belongs to?
Belongs to the GlgS family.
Protein: ASSY_BACMK
Sequence: MEKKKVVLAYSGGLDTSVAIKWLQEKNYDIIALCLDLGEGKDLAFVKEKALSVGAIKSYMIDVQEEYANEYALIAMQAHTLYEGKYPLVSALSRPLIAKKLVEIAEQEGASAVAHGCTGKGNDQVRFEVSIQALNPYLEVIAPVREWKWSREEEIAYAKENDIPIPINLDSPFSIDQNLWGRSNECGILEDPWAAPPEEAYEMTLALEDTPNKPEFVEIGFEAGVPTTLNGTAYSLSELIKTLNALAGKHGVGRIDHVENRLVGIKSREVYECPAAMTLITAHKELEDLTLVKEVAHFKPMIEQKLTELIYNGLWFSPLKQALNAFLQETQKNVTGTVRVKLFKGHAIVEGRKSEYSLYDEKLATYTAQDEFNHDAAVGFISLFGLPTKVYSQVNQKKVEA
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLA1_ORYSJ
Sequence: MSSLRGLGNIARRWRELNGVSYWKGLLDPLDVDLRNNIINYGELSQAAYTGLNRERRSRYAGSCLFSRKDFLSRVDVSNPNLYVITKFIYAMCTVSLPDAFMIKSWSKAAWSKQSNWMGFVAVATDEGKEVLGRRDVVVAWRGTIRMVEWMDDLDISLVPASEIVRPGSADDPCVHGGWLSVYTSADPESQYNKQSARYQVLNEIKRLQDMYEHEETSITITGHSLGAALATINATDIVSNGYNKSCPVSAFVFGSPRVGNPDFQKAFDSAPDLRLLRIRNSPDVVPNWPKLGYSDAGTELMIDTGKSPYLKAPGNPLTWHDMECYMHGVAGTQGSNGGFKLEIDRDIALVNKHEDALKNEYAIPSSWWVVQNKGMVKGTDGRWHLADHEDDD
What is the function of this protein?
Acylhydrolase that catalyzes the hydrolysis of phospholipids at the sn-1 position.
What are the official names of this protein?
Phospholipase A1-II 1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_ENTFA
Sequence: MSEAAIAKKETLVQAAAEKFESAASVVIVDYRGLTVEEVTNLRKQLRDAGVEMKVIKNSILSRAAKKVGLDGLDEVFTGPTAVAFSNDDVVAPAKIIDEFAKDAKALEIKGGVIEGKVSSVEQITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAEKNEEVA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: HEM1_THEM4
Sequence: MKLNLVGLGRNTPIYILEKFDFDEQEFFSSLKVKTTEVAVLKTCHRREIYYIGDKEPLTINEIIEPYIIRKSGIDVVRHLFKVSCGLDSMVLGEHQILSQVKNTHKNFCHGKILNKLFNEAVSLGKEARTKTGINKYPLSISYIAVKLIEEQINIEGKKIFVIGTGMMGQKVIKYLVSRGADIYISNRTIKKAYEIKKMFSEVNIVDFEEKYKHISSSDVVISATNAPHYVVEEKKVNSQKNIIFIDLSMPRNIEPSIKEYHTLYTLEDLNEISKKYNKLRQEKISTIQNLIETRIKKFLTWYKLQTVKDDILYIQNLAEKLVYEEIEKLSKKILLDDNSLKQIQKSLKSCTKKIVSYHINYIKEKVI
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: RSMH_RICRS
Sequence: MIQSHVSVMLNEMLEALSPKAGESYLDCTFGAGGYSKAILESCNCYVTALDRDPNVIKRAEEIQQNYGERFDFVETNFADSFAKLKEKKFDGIVLDLGVSSMQLDIADRGFSFLHDGPLDMRMSGQGLSAEEFVNAAEEKELADVIYKYGDESFSRRIAKRIVEYRKTARIDSTGKLAEIVRSSIGFRKGKIDPATKTFQAIRIYVNDELGELEQFLVNVKNILKKDGRLVVVSFHSLEDRIVKNFFKENSEKPVVRSKYAKDDMTIDPNKWLKIITNKALAPSDKEVGLNIRARSAKLRAAKAIYE
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 1OKO_GORGO
Sequence: MAVVAPRTLLLLLSGTLALTRTWAGSHSMRYFYTTMSRPGRGEPRFISVGYVDDTQFVRFDSDDASPREEPRAPWMEREGPEYWDRNTQIYKAQAQTDRVDLETLRGYYNQSEGGSHTIQRMYGCEVGPDGRFLRGYLQDAYDGKDYITLNEDLRSWTAADMAAQITQRKWEAAREAERLRAYMEGTCVEWLRRHLENGKETLQRTDPPKTHMTHHPVSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPGGDGTFQKWAAVVVPSGKEQRYTCHVQHEGLPKPLTLRWEPSSQPTIPIVGIIAGLVLLGAVITGAVVAAMMWRKKSSGRKGGSYSQAASSDSAQGSDVSLTA
What is the function of this protein?
Involved in the presentation of foreign antigens to the immune system.
What are the official names of this protein?
Class I histocompatibility antigen, Gogo-OKO alpha chain.
What is the protein family that this protein belongs to?
Belongs to the MHC class I family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PRC3A_XENLA
Sequence: RRRRSQGSEVNLTGQGQPCHSCGERCPGFLAHRWRKICQHCQCPWEEHGHTASNQDLERSLCRLVSGSQRDSLCESSSDSSVEKYAWVPSGLNPVQVHQFFKCFPEKKIPFINSPGEKYRLKQLLHQLPPHDSEARYCCSLQGEEEEELLLLFSQKRRLENLGRGCVRPVSGTMSGTVCQQCGHQISVGDVAVFASRAGLGFCWHPQCFTCAQCLELLCDLIYFYQDGKVYCGRHHAELKRPRCLACDEVIFSLECTEAEGFHWHTRHFCCFECECPLGGQRYIMKDQRPFCCSCYERLYAQYCDSCGECIGIDEGQLTYGGQHWHASESCFRCGRCGVCLLGRPFLPRHGQIYCSRSCSVLNATPESSFSPSQTDLSFQKETKDVGTSTNHELDGDSINDCTLSGSRRSLSIIDQTPISRAAPIRSLHSSLRGAPKEFSRECPNRRSLPDLNSHTRTPTRVTFQLPLSSEVKESVSLSHPSFTSSSSSDEEEGYFLGEPIPLPPFLRPPGYSAPPTHAPTSTTKKKKKKKDKSCLLS
What is the function of this protein?
Involved in the planar cell polarity (PCP) pathway that is essential for the polarization of epithelial cells during morphogenetic processes, including gastrulation and neurulation (PubMed:26079437, PubMed:27658614).  PCP is maintained by two molecular modules, the global and the core modules (PubMed:23140624).  Proteins of the core module include the proteins Frizzled (Fz), Disheveled (Dsh), Van Gogh (Vang), Prickle (Pk), Flamingo (Fmi, Celsr) and Diego (Dgo) (PubMed:23140624).  The core module proteins develop subcellular asymmetry, accumulating in two groups on opposite sides of epithelial cells (PubMed:23140624).  Distinct proximal (Vang, Pk and Fmi) and distal (Fz, Dsh, Dgo and Fmi) complexes segregate to opposite sides of the cell, where they interact with the opposite complex in the neighboring cell at or near the adherents junctions (PubMed:23140624).  Directional information to orient polarization with respect to the tissue axes is provided by the global module which involves Wnt proteins (PubMed:23140624).  Involved in the organization of the basal body (PubMed:27062996).  Involved in cilia growth and positioning (PubMed:27062996).  Required for proper assembly, stability, and function of mitochondrial membrane ATP synthase (mitochondrial complex V) (By similarity).
What are the official names of this protein?
Prickle planar cell polarity protein 3-A, LIM domain only protein 6-A, LMO6-A, Prickle-like protein 3-A, Pk3-A.
What is the protein family that this protein belongs to?
Belongs to the prickle / espinas / testin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion. Note=Recruited by vangl2 to anterior cell borders. This polarity is controlled by wnt proteins (PubMed:27658614). Wtip is involved in the recruitment of prickle3 to the basal body (PubMed:27062996).
Protein: SECA_STRP1
Sequence: MANILRKVIENDKGELRKLEKIAKKVESYADQMASLSDRDLQGKTLEFKERYQKGETLEQLLPEAFAVVREAAKRVLGLFPYRVQIMGGIVLHNGDVPEMRTGEGKTLTATMPVYLNAIAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKSPAEKREAYNCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEARTPLIVSGAVSSETNQLYIRADMFVKTLTSVDYVIDVPTKTIGLSDSGIDKAESYFNLSNLYDIENVALTHFIDNALRANYIMLLDIDYVVSEDGEILIVDQFTGRTMEGRRFSDGLHQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIPIPTNRPIARIDHTDLLYPTLESKFRAVVEDVKTRHAKGQPILVGTVAVETSDLISRKLVEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMRRFGSDRIKAFLDRMKLDEEDTVIKSGMLGRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANRDLGPEIKAMIKRTIDRAVDAHARSNRKDAIDAIVTFARTSLVPEEFISAKELRGLKDDQIKEKLYQRALAIYDQQLSKLRDQEAIIEFQKVLILMIVDNKWTEHIDALDQLRNAVGLRGYAQNNPVVEYQAEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERASQRATTAAPQNIQSQQSANTDDLPKVERNEACPCGSGKKFKNCHGRKSFS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: AB17C_RAT
Sequence: MPEPGPRMNGFSLGELCWLFCCPPCPSRIAAKLAFLPPEPTYTVLAPEQRAPAPAATPAPAPAAQPAPAEEGAGPGACSLHLSERADWQYSQRELDAVEVFFSRTARDNRLGCMFVRCAPSSRYTLLFSHGNAVDLGQMCSFYIGLGSRINCNIFSYDYSGYGVSSGKPSEKNLYADIDAAWQALRTRYGVSPENIILYGQSIGTVPTVDLASRYECAAVILHSPLMSGLRVAFPDTRKTYCFDAFPSIDKISKVTSPVLVIHGTEDEVIDFSHGLAMYERCPRAVEPLWVEGAGHNDIELYAQYLERLKQFISHELPNS
What is the function of this protein?
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins.  Has depalmitoylating activity towards DLG4/PSD95.
What are the official names of this protein?
Alpha/beta hydrolase domain-containing protein 17C, Abhydrolase domain-containing protein 17C.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. ABHD17 family.
What are the subcellular locations of this protein?
Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Cell projection, dendritic spine. Postsynaptic density membrane.
Protein: MURB1_BACAN
Sequence: MEQLVNELIQANVGRVLVDEPLARYTTMKIGGPADILIVPKRVAGIEKTLQLVKKYKTKWTVIGRGSNLLVSDLGIEGVVIRLGEGLDHLEVEKHRVRVGGGYPLIKLSTLLSRQGLAGLEFASGIPGSVGGAVYMNAGAHKSDISNILSKALILFEDGTIDWLTHGEMEFSYRTSVLQTKRPGIVLEAEFQLQIGERERIVSVMQKNKDYRRETQPWNHPCAGSVFRNPTPYFAGDLIEKAGLRGYQIGGAQISEMHGNFIINTGGASAQDVLSLIALIKQTIKDKFGVEMHTEVEIIGR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase 1, UDP-N-acetylmuramate dehydrogenase 1.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BET_FOAMV
Sequence: MDSYEKEESVASTSGIQDLQTLSELVGPENAGEGELTIAEEPEENPRRPRRYTKREVKCVSYHAYKEIEDKHPQHIKLQDWIPTPEEMIAQKVQNQDLGTILSFDVTCLKSITSLGRNDPGDDPSIMSHVLPVVTPWPMSQDHYAPTLFGILDRYYQGYLKSPATYQTWKFTCQVDPSGKRFMETQFWVPPLGQVNIQFYKNYQILTCCQAVDPFANIFHGTDEEMFDIDSGPDVWCSPSLCFKVIYEGAMGQKQEQKTWLCRLGHGHRMGACDYRKVDLYAMRQGKENPYGDRGDAALQYAYQVKRGCKAGCLASPVLNYKALQFHRTIMADFTNPRIGEGHLAHGYQAAMEAYGPQRGSNEERVWWNVTRNQGKQGGEYYREGGEEPHYPNTPAPHRRTWDERHKVLKLSSFATPSDIQRWTTKALPYGWKVVTESGNDYTSRRKIRTLTEMTQDEIRKRWESGYCDPFIDSGSDSDGPF
What is the function of this protein?
Bet counteracts the innate antiretroviral activity of APOBEC3 family defense factors by inhibiting their incorporation into virions.  May be implicated in the establishment and/or maintenance of viral persistance.  Bet is required for viral replication (By similarity).
What are the official names of this protein?
Protein Bet.
What are the subcellular locations of this protein?
[Isoform Bet]: Host cytoplasm. Host nucleus. Secreted. Note=Bet is highly expressed in infected cells, where it localizes to both cytoplasm and nucleus (PubMed:11884565). Also secreted and internalized by non-infected surrounding cells (PubMed:11884565). SUBCELLULAR LOCATION: [Isoform Bel-2]: Host nucleus.
Protein: TUSD_YERPG
Sequence: MSALKYCLLVTGPAYGTQQASSAYQFAQAVVGAGHHLVSIFFYREGVLNANQLTAPASDEFDLVRAWQQLAAEQAVTLNVCVAAALRRGITDQHEAEQLNLAAANLQPGFTLSGLGALAEATLTCDRMVQF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Accepts sulfur from TusA and transfers it in turn to TusE.
What are the official names of this protein?
Sulfurtransferase TusD, tRNA 2-thiouridine synthesizing protein D.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJZC_SCHPO
Sequence: MSQKSYIVQLKDSVDPASMDKIKSDLEASGAKIGHTYDTVFKGFSVSLPENAVDALSAHPEIQHFEPDQEMHTMKKD
What are the official names of this protein?
Uncharacterized protein C338.12.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I9 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: BTUC_ECOLU
Sequence: MLTLARQQQRQNIRWLLCLSVLMLLALLLSLCAGEQWISPGDWSTPRGELFVWQIRLPRTLAVLLVGAALAISGAVMQALFENPLAEPGLLGVSNGAGVGLIAAVLLGQGQLPNWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGVALGIICSALMTWAIYFSTSVDLRQLMYWMMGGFGGVDWRQSWLMLALIPVLLWICCQSRPMNMLALGEISARQLGLPLWFWRNVLVAATGWMVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGASALLLADVVARLALAAAELPIGVVTATLGAPVFIWLLLKAGR
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Involved in the translocation of the substrate across the membrane.
What are the official names of this protein?
Vitamin B12 import system permease protein BtuC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS3A_TOBAC
Sequence: MAVGKNKRISKGKKGGKKKAADPYAKKDWYDIKAPSVFDIKNVGKTLVTRTQGTKIASEGLKHRVFEVSLADLQKDEDQSFRKIRLRAEDVQGKNVLTNFWGMDFTTDKLRSLVKKWQTLIEAHVDVKTTDSYTLRMFCIAFTKKRPNQQKRTCYAQSSQIRQIRRKMVEIMRNQASSCDLKELVAKFIPESIGREIEKATSSIFPLQNVYIRKVKILKAPKFDIGKLMEVHGDYSEDVGVKLDRPADETVAEAEPEIPGA
What are the official names of this protein?
40S ribosomal protein S3a, Protein cyc07.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_WIGBR
Sequence: MTRKSIQEREKKRIKLAKTFLKKRKELKKIISDPNIGNDIRWNAVLKLQSLPRDSSLSRQRNRCSQTSRPHAFLRKFGLSRIKLREAAMRGEIPGLRKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: RSMH_NITWN
Sequence: MTAPPIRHVPVLGREAVAMLAPRAGGVYVDATFGAGGYSRAILATAETRVIGIDRDPTAIAGGSGLVEESGGRLILVEDRFSHLAAVCAAQDAAAVDGVVMDVGVSSMQLDEAGRGFSFRLDGPLDMRMSGHGPTAAEVVARASETDLADIIYIFGEERRSRAVARAIVGARRHGPIATTRALADIVSKVVRAKPHEIHPATRTFQALRIFVNEELDELIAALAAAERVLKPGGRLAVVSFHSLEDRIVKNFLAWRGKTGGGSRHRPEIERAPPSFAILTKRPLTPGDDEVQANPRARSARLRAAERTDAAAIDDGAELPAWPSLANVMRGG
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL333_KINRD
Sequence: MAKTTDVRPKITMACTECKERNYITKKNRRNDPDRLDLAKFCPRCGKKTTHRETR
What are the official names of this protein?
50S ribosomal protein L33 3.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: NEP_I45A0
Sequence: MDPNTVSSFQDILMRMSKMQLGSSSEDLNGMITQFESLKLYRDSLGEAVMRMGDLHSLQNRNGKWREQLGQKFEEIRWLIEEVRHRLKITENSFEQITFMQALQLLLEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: RL43A_YEAST
Sequence: MAKRTKKVGITGKYGVRYGSSLRRQVKKLEIQQHARYDCSFCGKKTVKRGAAGIWTCSCCKKTVAGGAYTVSTAAAATVRSTIRRLREMVEA
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L43-A, L37a, Large ribosomal subunit protein eL43-A, YL35.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL43 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMM1_NEIMB
Sequence: MNTLQKGFTLIELMIVIAIVGILAAVALPAYQDYTARAQVSEAILLAEGQKSAVTEYYLNHGEWPGNNTSAGVATSSEIKGKYVKSVEVKNGVVTAQMASSNVNNEIKGKKLSLWAKRQNGSVKWFCGQPVTRDKAKAANDDVTAAAAANGKKIDTKHLPSTCRDASDAS
What is the function of this protein?
Major component of the type IV pilus (T4P) that plays a role in cellular adherence, microcolony formation as well as twitching motility.
What are the official names of this protein?
Fimbrial protein, Pilin.
What is the protein family that this protein belongs to?
Belongs to the N-Me-Phe pilin family.
What are the subcellular locations of this protein?
Fimbrium. Membrane; Single-pass membrane protein.
Protein: SYE_VIBC1
Sequence: MTVKTRFAPSPTGYLHVGGARTALYSWLYAKNQGGEFVLRIEDTDLERNSQEAVDAILEGMEWLGLEWNEGPYFQTQRFDRYNEMVDKLLEEDKAYKCYASKELLDEVRAEQEANKEMPRYDANHPKIKAANEAAKDGEPCVIRFRNPKEGSVVFDDQIRGRIEISNTQMDDLIIRRTDGSPTYNFCVVVDDWDMGITHVVRGEDHINNTPRQINIYEALGAPVPTFAHCAMILGDDGAKLSKRHGAVSVMQYRDMGYLPAALNNYLVRLGWSHGDQEIFTQEEMINLFSLNAVSKSASAFNTDKLQWLNNHYIKNSDPAYVAEHLQWHLDQQKLDVTNGPAITEVIKLVGERCNTLVELAEQIGYFYEDFAEFEAGAAKKHLRGVAKEPLELALAKAEALTEWTTANIKDGVIAAVCEELEIGMGKIGMPLRVAVTGGGQSPSVDAVMELIGKERCVARIKMALEFIAEREANA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_LACLS
Sequence: MAKQVEKLVKLQIPAGKATPAPPVGPALGQAGVNIMGFTKEFNARTADQAGMIIPVVISVYDDKSFTFITKTPPAAVLLKKAAGVQKGSGEPNKTKVASVTKAQIKEIAELKMPDLNAASVETAMSMIEGTAKSMGFTVTD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.