PharMolix/UniProtQA huggingface dataset:
Protein: RS24_MACFA
Sequence: MNDTVTIRTRKFMTNRLLQRKQMVIGVLHPGKATVPKTEIREKLAKMYKTTPDVIFVFGFRTHFGGGKTTGFGMIYDSLDYAKKNEPKHRLARHGLYEKKKTSRKQRKERKNRMKKVRGTAKANVGAGKKK
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
40S ribosomal protein S24.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS24 family.
Protein: K2C7_MOUSE
Sequence: MSIHFSSRSTAYPGRGAQVRLSSGRASFGSRSLYGLGSSRPRVAVRSAYGGPVGAGIREITINQSLLAPLSVDIDPTIQQVRQEEREQIKTLNNKFASFIDKVRFLEQQNKMLETKWALLQEQKSAKSSQLPRIFEAQIAGLRQQLETLQLDGGRLEVELRNMQDVVEDFKNKYEEEINRRTAAENEFVLLKKDVDAAYTNKVELEAKADSLQDEINFLKTLHETELAELQSQISDTSVVLSMDNSRSLDLDGIIADVKAQYEEMANHSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEIAEMNRSIQRLQAEIDTLKNQRAKLESSIAEAEEQGELAIKDAHAKQGELEAALQKAKQDVARQLREYQELLNTKLALDIEIATYRKLLEGEESRLSGDGMGPVNISVVNSTGGNGGKLIFGGTMGSNALSFSGGPGALRAYSIKTTSTTRRGTHN
What is the function of this protein?
Blocks interferon-dependent interphase and stimulates DNA synthesis in cells.
What are the official names of this protein?
Keratin, type II cytoskeletal 7, Cytokeratin-7, CK-7, Keratin-7, K7, Type-II keratin Kb7.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: RL39_BOVIN
Sequence: MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL
What is the function of this protein?
RNA-binding component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L39.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL39 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_BURM1
Sequence: MSMSDPIADMLTRIRNAQMVEKVSVAMPSSKVKVAIAQVLKDEGYIDDFAVKTEGAKAELNIALKYYAGRPVIERLERVSKPGLRVYRGRNEIPQVMNGLGVAIVSTPKGVMTDRKARATGVGGEVICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RBL_PROM9
Sequence: MSKKYDAGVKEYRDTYWTPEYVPLDTDLLACFKCTGQEGVPREEVAAAVAAESSTGTWSTVWSELLTDLEFYKGRCYRIEDVPGDPEAFYAFIAYPLDLFEEGSITNVLTSLVGNVFGFKALRHLRLEDIRFPIAFIKTCGGPPNGIVVERDRLNKYGRPLLGCTIKPKLGLSGKNYGRVVYECLRGGLDLTKDDENINSQPFQRWRERFEFVAEAVKLAQQETGEVKGHYLNCTANTPEELYERAEFAKELDMPIIMHDYITGGFTANTGLANWCRKNGMLLHIHRAMHAVIDRHPKHGIHFRVLAKCLRLSGGDQLHTGTVVGKLEGDRQTTLGYIDNLRESFVPEDRSRGNFFDQDWGSMPGVFAVASGGIHVWHMPALLAIFGDDSCLQFGGGTHGHPWGSAAGAAANRVALEACVKARNAGREIEKESRDILMEAAKHSPELAIALETWKEIKFEFDTVDKLDVQG
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Carboxysome.
Protein: RS3_BORA1
Sequence: MGQKIHPTGFRLAVTRNWSSRWYADDKDFGGMLAEDIRVREYLKKKLKSASVGRVVIERPAKNARITVYSARPGVVIGKRGEDIESLKADLQRLMGVPVHVNIEEIRKPETDAQLIADSISQQLEKRIMFRRAMKRAMQNAMRLGAQGIKIMSSGRLNGIEIARTEWYREGRVPLHTLKANIDYGTSEAHTTYGVIGIKVWVYKGDMLANGELPVETAAPREEERRPRRAPRGDRPDGARNGRPGGGRGRAPRKADAAPAPEGE
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: ADCA_STRP3
Sequence: MKKKILLMMSLISVFFAWQLTQAKQVLAEGKVKVVTTFYPVYEFTKGIVGNDGDVSMLMKAGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVSDVKKSLTSKKVTIVKGTGNMLLVAGVGHDHHHEEADKKHEHNKHSEEGHNHAFDPHVWLSPYRSITVVENIRDSLSKAYPEKAENFKANAATYIEKLKELDKDYTAALSDAKQKSFVTQHAAFGYMALDYGLNQISINGVIPDAEPSAKRIATLSKYVKKYGIKYIYFEENASSKVAKTLAKEAGVKAAVLSPLEGLTEKEMKAGQDYFTVMRKNLETLRLTTDVAGKEILPEKDTTKTVYNGYFKDKEVKDRQLSDWSGSWQSVYPYLQDGTLDQVWDYKAKKSKGKMTAAEYKDYYTTGYKTDVEQIKINGKKKTMTFVRNGEKKTFTYTYAGKEILTYPKGNRGVRFMFEAKEPNAGEFKYVQFSDHAIAPEKAEHFHLYWGGDSQEKLHKELEHWPTYYGSDLSGREIAQEINAH
What is the function of this protein?
Part of the ATP-driven transport system AdcABC for zinc.
What are the official names of this protein?
Zinc-binding protein AdcA.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 9 family.
Protein: TUSD_ECO7I
Sequence: MRFAIVVTGPAYGTQQASSAFQFAQALIAEGHELSCVFFYREGVYNANQLTSPASDEFDLVRGWQQLNAQHGVALNICVAAALRRGIVDETEAGRLGLASSNLQSGFTLSGLGALAEASLTCDRVVQF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Accepts sulfur from TusA and transfers it in turn to TusE.
What are the official names of this protein?
Sulfurtransferase TusD, tRNA 2-thiouridine synthesizing protein D.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCAD_ECOLI
Sequence: MSTYTQPVMLLLSGLLLLTLAIAVLNTLVPLWLAQEHMSTWQVGVVSSSYFTGNLVGTLLTGYVIKRIGFNRSYYLASFIFAAGCAGLGLMIGFWSWLAWRFVAGVGCAMIWVVVESALMCSGTSRNRGRLLAAYMMVYYVGTFLGQLLVSKVSTELMSVLPWVTGLTLAGILPLLFTRVLNQQAENHDSTSITSMLKLRQARLGVNGCIISGIVLGSLYGLMPLYLNHKGVSNASIGFWMAVLVSAGILGQWPIGRLADKFGRLLVLRVQVFVVILGSIAMLSQAAMAPALFILGAAGFTLYPVAMAWACEKVEHHQLVAMNQALLLSYTVGSLLGPSFTAMLMQNFSDNLLFIMIASVSFIYLLMLLRNAGHTPKPVAHV
What are the official names of this protein?
Uncharacterized MFS-type transporter YcaD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DRL40_ARATH
Sequence: MGGCVSVSISCDQLTKNVCSCLNRNGDYIHGLEENLTALQRALEQIEQRREDLLRKILSEERRGLQRLSVVQGWVSKVEAIVPRVNELVRMRSVQVQRLCLCGFCSKNLVSSYRYGKRVMKMIEEVEVLRYQGDFAVVAERVDAARVEERPTRPMVAMDPMLESAWNRLMEDEIGILGLHGMGGVGKTTLLSHINNRFSRVGGEFDIVIWIVVSKELQIQRIQDEIWEKLRSDNEKWKQKTEDIKASNIYNVLKHKRFVLLLDDIWSKVDLTEVGVPFPSRENGCKIVFTTRLKEICGRMGVDSDMEVRCLAPDDAWDLFTKKVGEITLGSHPEIPTVARTVAKKCRGLPLALNVIGETMAYKRTVQEWRSAIDVLTSSAAEFSGMEDEILPILKYSYDNLKSEQLKLCFQYCALFPEDHNIEKNDLVDYWIGEGFIDRNKGKAENQGYEIIGILVRSCLLMEENQETVKMHDVVREMALWIASDFGKQKENFIVQAGLQSRNIPEIEKWKVARRVSLMFNNIESIRDAPESPQLITLLLRKNFLGHISSSFFRLMPMLVVLDLSMNRDLRHLPNEISECVSLQYLSLSRTRIRIWPAGLVELRKLLYLNLEYTRMVESICGISGLTSLKVLRLFVSGFPEDPCVLNELQLLENLQTLTITLGLASILEQFLSNQRLASCTRALRIENLNPQSSVISFVATMDSLQELHFADSDIWEIKVKRNETVLPLHIPTTTTFFPNLSQVSLEFCTRLRDLTWLIFAPNLTVLRVISASDLKEVINKEKAEQQNLIPFQELKELRLENVQMLKHIHRGPLPFPCLQKILVNGCSELRKLPLNFTSVPRGDLVIEAHKKWIEILEWEDEATKARFLPTLKAFPENIDADGYEISF
What is the function of this protein?
Probable disease resistance protein.
What are the official names of this protein?
Probable disease resistance protein At5g63020, pNd11.
What is the protein family that this protein belongs to?
Belongs to the disease resistance NB-LRR family.
Protein: NDUA4_PONPY
Sequence: MLRQILSQAKKHPSLIPLFVFIGTGASGATLYLLRLALFNPDVCWDRNNPEPWNKLGPNDQYKFYSVNVDYSKLKKERPDF
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules unsing 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.  NDUFA4 is required for complex IV maintenance.
What are the official names of this protein?
Cytochrome c oxidase subunit NDUFA4.
What is the protein family that this protein belongs to?
Belongs to the complex IV NDUFA4 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: C1TC_RAT
Sequence: MAPAGILNGKVVSAQIRNRLKTQVTQMQEQVPGFTPGLAILQVGDRDDSNLYINVKLKAAQEIGIKATHIKLPRTSTESEVLKYVISLNEDATVHGFIVQLPLDSENSINTEAVINAIAPEKDVDGLTSINAGKLARGDLKDCFIPCTPKGCLELIKETGVQIAGRHAVVVGRSKIVGAPMHDLLLWNNATVTTCHSKTADLDKEVNKGDILVVATGQPEMVKGEWIKPGAVVIDCGINYVPDDTKPNGRKVVGDVAYDEAKEKASFITPVPGGVGPMTVAMLMQSTVESAQRFLKKFKPGKWTIQYNKLNLKTPVPSDIAISRSCKPKLIGNLAREIGLLTEEVELYGETKAKVLLSALDRLKHQPDGKYVVVTGITPTPLGEGKSTTTIGLVQALGAHLHQNVFACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLVAAAIDARIFHELTQTDKALFNRLVPSVNGVRKFSDIQIRRLRRLGIEKTDPAALTDDEINRFARLDIDPETITWQRVLDTNDRFLRKITIGQAPTEKGHTRTAQFDISVASEIMAVLALTSSLEDMRARLGKMVVASSKKGEPISCEDLGVSGALTVLMKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSIIADRIALKLVGPEGFVVTEAGFGADIGMEKFFNIKCRYSGLQPHVVVLVATVRALKMHGGGPTVTAGLPLPKAYTEEDLDLVEKGFSNLRKQIENARMFGVPVVVAMNAFKTDTDTELDLIGRLSREHGAFDAVKCTHWAEGGQGALALAQAVQRASQAPSSFQLLYDLKLSVEDKIRIIAQKIYGADDIELLPEAQNKAEIYTKQGFGNLPICMAKTHLSLSHNPEQKGVPTGFVLPIRDIRASVGAGFLYPLVGTMSTMPGLPTRPCFYDIDLDPETEQVNGLF
What is the function of this protein?
Trifunctional enzyme that catalyzes the interconversion of three forms of one-carbon-substituted tetrahydrofolate: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate, 5,10-methenyltetrahydrofolate and (6S)-10-formyltetrahydrofolate.  These derivatives of tetrahydrofolate are differentially required in nucleotide and amino acid biosynthesis, (6S)-10-formyltetrahydrofolate being required for purine biosynthesis while (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate is used for serine and methionine biosynthesis for instance.
What are the official names of this protein?
C-1-tetrahydrofolate synthase, cytoplasmic, C1-THF synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GC76C_DROME
Sequence: MTRWPFNLLLLLSVAVRDCSNHRTVLTVGYLTALTGDLKTRQGLAISGALTMALDEVNKDPNLLPNVYLDLRWNDTKGDTVLATKAITEMICDGIATIFGPEGPCYVEAIVSQSRNIPMISYKCAEYRASAIPTFARTEPPDTQVVKSLLALLRYYAWNKFSILYEDVWSPVADLLKDQATKRNMTINHKQSFIDNRVKCCEQMLDCCRSGYWYQLVQNTMNRTRIYVFLGAANSLVDFMSSMETAGLFARGEYMVIFVDMMVYSEREAEKYLRRVDQITFMSNCHSTENFNQMARSLLVVASTPPTKDYIQFTKQVQKYSSKPPFNLEIPRLFVESNFSKFISIYAAYLYDSVKLYAWAVDKMLREETRVLTDDVIFEVASNGTRVIDTIIKNRTYMSITGSKIKIDQYGDSEGNFSVLAYKPHKWNNSNNMPCNYHMVPVAYFHQGEEHPEYKLINGSIDWPSGGEKPADEPMCGFANELCKKDDTHYTSTVAAVVLGVLLFCSGVITMSIYRKWKIELEIEGLLWKIDPNEIKGYSGNEIVSSPSKVSLMSAQSYGSRWTNQFVTSTGRLRGAVVRIKELKFPRKRDISREIMKEMRLLRELRHDNINSFIGASVEPTRILLVTDYCAKGSLYDIIENEDIKLDDLFIASLIHDLIKGMIYIHNSQLVYHGNLKSSNCVVTSRWMLQVTDFGLHELRQCAENESIGEHQHYRNQLWRAPELLRNHIHGSQKGDVYAFAIIMYEIFSRKGPFGQINFEPKEIVDYVKKLPLKGEDPFRPEVESIIEAESCPDYVLACIRDCWAEDPEERPEFSVIRNRLKKMRGGKTKNIMDQMMEMMEKYANNLEDIVTERTRLLCEEKMKTEDLLHRMLPQSVAEKLTMGQGVEPVSYDLVTIYFSDIVGFTAMSAESTPLQVVNFLNDLYTVFDRIIRGYDVYKVETIGDAYMVVSGLPIKNGDRHAGEIASMALELLHAVKQHRIAHRPNETLKLRIGMHTGPVVAGVVGLTMPRYCLFGDTVNTASRMESNGEALKIHISNKCKLALDKLGGGYITEKRGLVNMKGKGDVVTWWLTGANENAIQKKLVDMMDMPPPLFSRPRKSPKLNPDSRQPSIQAMHFCGTGSRRQSTVPRAMDGESTYSLQGSVRESPRMVSKRDRDRERPPINGLGAGHFVGGALLESAQASLSTLNHSETNETNCDMDGGSGGVSGSGSGLVRQPNALHKPLAMVRPHRIISAAQLPQLGDNDDDSADTLLRESRSLDPMPMQQLRKRHDRVKLPPSKLSKNNSRSLDTGVSLISGNPNGEVHSSQLDLDNEMTANPVDATDGYDDELGLLMRHDNGQLPALRYSGSFPNAQISIVPTGRSAGGGGGGREGGGSNCAKHLNNNCNGGVNVEDDLESPLLQRQASLSVPPEEMLAHNKRWHSLEHMDGPGGHGGNSVSYAADIDNRHPGDLDFFSGSSNQHHRSKAAGGSKLTNWMTNIFKGNGVRSGEARRVGILPSGVHGARTGFTDMAASAAARDRESIV
What is the function of this protein?
Guanylate cyclase involved in the production of the second messenger cGMP (PubMed:24284209).  Acts as a receptor for the NPLP1-4 peptide and modulates the innate immune IMD pathway in response to salt stress by inducing nuclear translocation of NF-kappa-B protein Rel which leads to increased expression of the antimicrobial peptide diptericin (PubMed:21893139).  Plays a role in Sema-1a-mediated axon repulsion which is required for the correct establishment of neuromuscular connectivity (PubMed:15282266, PubMed:24284209).  Required in developing embryonic somatic muscle for correct patterning of ventral and lateral muscles and for localization of integrin beta-ps at developing dorsal muscle myotendinous junctions (PubMed:23213443).  Required for invagination, migration and lumen shape of the embryonic salivary gland by regulating the localization of the integrin-binding protein rhea/Talin to the visceral mesoderm surrounding the gland and maintaining the laminin matrix (PubMed:23862019).  Required in the developing wing to regulate extracellular matrix (ECM) organization by activating the cGMP-dependent protein kinase For which represses the activity of matrix metalloproteases such as Mmp2 and decreases ECM matrix reorganization (PubMed:26440503).
What are the official names of this protein?
Receptor-type guanylate cyclase Gyc76C, DrGC-1.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: NRDR_CHLAD
Sequence: MRCPICHFPETDVIDTRKLYEGEVIRRRRKCRACGRRFTTYERIESVSLMVVKKDGTREPYDREKIARGVRTACYRRPVSADAIEQLVNEVETAVMATDQQEISSQFIGDAVMRRLRDLDEVAYIRFASVYRSFADIGKLREAVDELLEREGTRNGHSSAATTDQGTTDNHSRM
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: EXOX_ECOL6
Sequence: MLRIIDTETCGLQGGIVEIASVDVIDGKIVNPMSHLVRPDRPISPQAMAIHRITEAMVADKPWIEDVIPHYYGSEWYVAHNASFDRRVLPEMPGEWICTMKLARRLWPGIKYSNMALYKTRKLNVQTPPGLHHHRALYDCYITAALLIDIMNTSGWTAEQMADITGRPSLMTTFTFGKYRGKAVSDVAERDPGYLRWLFNNLDSMSPELRLTLKHYLENT
What is the function of this protein?
Capable of degrading both single-strand and double-strand DNA with 3' to 5' polarity.  Has higher affinity for ssDNA ends than for dsDNA (By similarity).
What are the official names of this protein?
Exodeoxyribonuclease 10, Exodeoxyribonuclease X, Exo X, Exonuclease X.
Protein: TRMB_PROM1
Sequence: MRQHVNPLSQFFQLPLSLPSKNILFEKSHYPIHLDIGSAKGEFLIELATKYPDWNFVGLEIREPLVSLCEKKRRKLELTNLKFLFCNVNVSLDEWLSDLDFGQLKRVSIQFPDPWFKRKHFKRRVLNTNILNSIAKSMSKDGEIFIQSDILKLIEYMTNTIDENRYFTRKNVGDLRSIDKNPYDVMTDREIFSLKKNLLIYRVMYIRNSLLFTN
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RISA_BUCBP
Sequence: MFTGIVRGLGKVVKILKEKKISQWEVETSNELVKNLMLGASISCNGCCLTVRNIFRTIFCVDIVEETLRSTSLNTIIVGQYINLERSIKFGEEVGGHLVSGHIITTGVVSDKKELFSNQELWISLSASFFIKYFFYKGFVCVDGISLTIGSIKNNAFCVFLIPETILRTTIGQKIIGDVVNIEIDFYTQITVDSVERLLKVHPSKFINCIDI
What is the function of this protein?
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
What are the official names of this protein?
Riboflavin synthase, RS.
Protein: FBPB_ACTPL
Sequence: MDSITNKRSLFESSHFWILLSLIAFIALPSKALDYGLLESTADEFLDAMGWSSVNLTILWFLPLIGFWLLPSLKLSTETQAKVELGLISFILLFAFISATIYKVSMGYSVIVLIATLTALATFAFAKLKMMQGDKFIIGALLSIILLIFFFIVYPTVAIFISMFYDGETFAPEQVVRILGQGYIVRVISNSLFLSGFVGIVSTVFGLAFALYTTRIAHRTAFIGKIFSILPIVTPPFVVGLGVTLMLGRSGYVTEFLDTYFGFKDHNWLYGFNGIAIAQILAFAPISFMILDGALKSIHPSIEEASYTLRANRYQTFYNIIFPLLRPALANSFLIVFIQSLADFSNPLVLGGSFDVIATQIYFYIAGSQLDYASASTLGSMLLIFSLLIFIVQYMWIGNRSYVTVSGKSYRGDVQDLPSGLKYTIIVMLGFWVVFNFALYGSIFYGSFTVNWGVDYTLTLNNYAMLFGQGLSDGAWPSLINTMIYAGIAAPLTALFGLLIAYIVVRKDFQGKKTLEFLTMLCFAVPGTVAGVSYILAFNDAPMYITGTGIIIIISMVMRDLPIGMRAAIAGLGQLDKSLDEASLSLKGSSLKTIWFIVFPLLKPALLSALVTSFVRAMTTVSAIVFLVTADTRVATAYILNRVEDGEYGVAIAYGSILIVVMMAIILFFDWIVGDTRIPKSQAKKAD
What is the function of this protein?
Part of the ABC transporter complex FbpABC (TC 3. A. 1. 10. 1) involved in Fe(3+) ions import.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Ferric transport system permease protein FbpB.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FbpB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ANM7_HUMAN
Sequence: MKIFCSRANPTTGSVEWLEEDEHYDYHQEIARSSYADMLHDKDRNVKYYQGIRAAVSRVKDRGQKALVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMADAAVKIVEKNGFSDKIKVINKHSTEVTVGPEGDMPCRANILVTELFDTELIGEGALPSYEHAHRHLVEENCEAVPHRATVYAQLVESGRMWSWNKLFPIHVQTSLGEQVIVPPVDVESCPGAPSVCDIQLNQVSPADFTVLSDVLPMFSIDFSKQVSSSAACHSRRFEPLTSGRAQVVLSWWDIEMDPEGKIKCTMAPFWAHSDPEEMQWRDHWMQCVYFLPQEEPVVQGSALYLVAHHDDYCVWYSLQRTSPEKNERVRQMRPVCDCQAHLLWNRPRFGEINDQDRTDRYVQALRTVLKPDSVCLCVSDGSLLSVLAHHLGVEQVFTVESSAASHKLLRKIFKANHLEDKINIIEKRPELLTNEDLQGRKVSLLLGEPFFTTSLLPWHNLYFWYVRTAVDQHLGPGAMVMPQAASLHAVVVEFRDLWRIRSPCGDCEGFDVHIMDDMIKRALDFRESREAEPHPLWEYPCRSLSEPWQILTFDFQQPVPLQPLCAEGTVELRRPGQSHAAVLWMEYHLTPECTLSTGLLEPADPEGGCCWNPHCKQAVYFFSPAPDPRALLGGPRTVSYAVEFHPDTGDIIMEFRHADTPD
What is the function of this protein?
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA.  Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles.  Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s.  Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites.  May also play a role in embryonic stem cell (ESC) pluripotency.  Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
What are the official names of this protein?
Protein arginine N-methyltransferase 7, Histone-arginine N-methyltransferase PRMT7, [Myelin basic protein]-arginine N-methyltransferase PRMT7.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
Protein: EFTS_KORVE
Sequence: MNISAAQVKDLREKTNAPMMDCKKALTEANGDIEQAIVILRKKGIASAAKKAARVTSEGSVVSYIHAGGKIGVLVEVNCESDFVARTEQFKELTHDIAMHIAASDPKFVRKEDVTPEYMEKEKEIYRDQAAKTGKPAPVIEKIVEGKMAKFYEEVCLLEQPFIKEQTISVGQLIATTIGKLGENISVKRFARFKVGDVGETVAISKASNEGEAEAPAAK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S35D2_HUMAN
Sequence: MTAGGQAEAEGAGGEPGAARLPSRVARLLSALFYGTCSFLIVLVNKALLTTYGFPSPIFLGIGQMAATIMILYVSKLNKIIHFPDFDKKIPVKLFPLPLLYVGNHISGLSSTSKLSLPMFTVLRKFTIPLTLLLETIILGKQYSLNIILSVFAIILGAFIAAGSDLAFNLEGYIFVFLNDIFTAANGVYTKQKMDPKELGKYGVLFYNACFMIIPTLIISVSTGDLQQATEFNQWKNVVFILQFLLSCFLGFLLMYSTVLCSYYNSALTTAVVGAIKNVSVAYIGILIGGDYIFSLLNFVGLNICMAGGLRYSFLTLSSQLKPKPVGEENICLDLKS
What is the function of this protein?
Antiporter transporting nucleotide sugars such as UDP-N-acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP-mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars).  May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling.
What are the official names of this protein?
UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter, Homolog of Fringe connection protein 1, HFRC1, SQV7-like protein, SQV7L, Solute carrier family 35 member D2, UDP-galactose transporter-related protein 8, UGTrel8.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. SLC35D subfamily.
Protein: GATB_PELPD
Sequence: MKYQAVIGLEVHVQLKTDSKIFCGCSTSFGSDPNSQTCPVCLGLPGALPVLNKKVVEFAIKAGLATNCSITQRSIFARKNYFYPDLPKGYQISQFEDPVCQWGWLDIELNGETKRIGITRIHMEEDAGKLVHADVPELEDGSGVDLNRACTPLLEVVSEPDLRSSDEAVSYLKQLHQIVTWLGICDGNMEEGSFRCDANVSVMEQGAEKFGTRAEIKNINSFRFVKQAIEYEIQRQIDLIEDGGTVVQETRLFDPDNGVTRSMRSKEEAHDYRYFPDPDLVPLVIDDDWIQRVRQGLPELPEHKKQRFMSEFSIPAYDAEVLTASRPLAEYYEECVACHHDGKAVSNWVMGEVTRGLNDSGLSIENCPVTPRLLGGLLKLMDNGTISGKIAKTVFDEMWKSGKEPAVIVEEQGLVQVSDNGAILAIIDEIMAKNQGQVAEYRSGKDKLFGFFVGQVMKASKGKANPSLVNELLLEKLKG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: Y2744_DROME
Sequence: METALAEVQLSCLLCEQTFDATEKLDEHLPTHFPQPVSTGQTCDICGRTMRSSLELHQHYKRYHEAHVPNTEGHFQCQLCDKVFLLQDHLKVHVKIEHATDGYQPDEKSLDWQHYSPRSLDTTNDYKLDPILCPPPKRKYPPRSPFFNPNLWLGADNCFM
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Uncharacterized zinc finger protein CG12744.
What are the subcellular locations of this protein?
Nucleus.