PharMolix/UniProtQA huggingface dataset:
Protein: CMOB_PSEPK
Sequence: MIDLSPLVRRLAGTPLASWSQGLQAQLDAKLEKGHGDLDRWRGALEALPALQPSEIDLVNGLRLDCDCDDATRAQMRQALMGLSPWRKGPFDLFGVHVDTEWRSDWKWSRVGPHLDLQGKRVLDVGCGNGYYQWRMLGAGADMVIGVDPNWLFFCQFQAVQQYLPELPAWHLPFALEDLPANLEGFDTVFSMGVFYHRRSPIEHLLALKDCLVKGGELVLETLVIEGDENQVLVPEDRYAQMRNVWYLPSVPALARWLRRAGFSDVRCVDVSVTSVEEQRSTDWMRYQSLSDFLDPNDHSKTVEGLPAPRRATLLARK
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: RNPH_ECOSE
Sequence: MRPAGRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIEEGVPRFLKGQGQGWITAEYGMLPRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAVDLKALGEFTITLDCDVLQADGGTRTASITGACVALADALQKLVENGKLKTNPMKGMVAAVSVGIVNGEAVCDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFTHEELLTLLALARGGIESIVATQKAALAN
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: TSAD_PSEA8
Sequence: MRVLGLETSCDETGVALYDSERGLLADALFSQIDLHRVYGGVVPELASRDHVKRMLPLIRQVLDESGCTPADIDAIAYTAGPGLVGALLVGASCAQAMAFAWGVPAVGVHHMEGHLLAPMLEEQPPRFPFVALLVSGGHTQLVRVDGIGRYQLLGESVDDAAGEAFDKTAKLIGLGYPGGPEIARLAELGTPGRFVFPRPMTDRPGLDFSFSGLKTFTLNTWQRCVEAGDDSEQTRCDIALAFQTAVVETLLIKCRRALKQTGLKNLVIAGGVSANQALRSGLEKMLGEMKGQVFYARPRFCTDNGAMIAYAGCQRLLAGQHDGPAISVQPRWPMESLPAV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_STRPQ
Sequence: MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTARDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVCHEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIEVSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDAKK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AROA_MANHA
Sequence: MEKLTLTPISRVEGEINLPGSKSLSNRALLLAALATGTTQVTNLLDSDDIRHMLNALKALGVKYELSDDKTVCVVEGIGGAFKVQNGLSLFLGNAGTAMRPLAAALCLKGAETAQIILTGEPRMKERPIKHLVDALRQVGAEVQYLENEGYPPLAISNSGLQGGKVQIDGSISSQFLTALLMSAPLAESDMEIEIIGDLVSKPYIDITLSMMNDFGITVENRDYKTFLVKGKQGYVAPQGNYLVEGDASSASYFLASGAIKGKVKVTGIGKKSIQGDRLFADVLEKMGAKITWGEDFIQAEQSPLKGVDMDMNHIPDAAMTIATTALFAEGETVIRNIYNWRVKETDRLTAMATELRKVGAEVEEGEDFIRIQPLALENFQHAEIETYNDHRMAMCFSLIALSNTEVTILDPNCTAKTFPTYFRELEKLSVR
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NARQ_ECOLI
Sequence: MIVKRPVSASLARAFFYIVLLSILSTGIALLTLASSLRDAEAINIAGSLRMQSYRLGYDLQSGSPQLNAHRQLFQQALHSPVLTNLNVWYVPEAVKTRYAHLNANWLEMNNRLSKGDLPWYQANINNYVNQIDLFVLALQHYAERKMLLVVAISLAGGIGIFTLVFFTLRRIRHQVVAPLNQLVTASQRIEHGQFDSPPLDTNLPNELGLLAKTFNQMSSELHKLYRSLEASVEEKTRDLHEAKRRLEVLYQCSQALNTSQIDVHCFRHILQIVRDNEAAEYLELNVGENWRISEGQPNPELPMQILPVTMQETVYGELHWQNSHVSSSEPLLNSVSSMLGRGLYFNQAQKHFQQLLLMEERATIARELHDSLAQVLSYLRIQLTLLKRSIPEDNATAQSIMADFSQALNDAYRQLRELLTTFRLTLQQADLPSALREMLDTLQNQTSAKLTLDCRLPTLALDAQMQVHLLQIIREAVLNAMKHANASEIAVSCVTAPDGNHTVYIRDNGIGIGEPKEPEGHYGLNIMRERAERLGGTLTFSQPSGGGTLVSISFRSAEGEESQLM
What is the function of this protein?
Acts as a sensor for nitrate/nitrite and transduces signal of nitrate/nitrite availability to the NarL/NarP proteins.  NarQ probably activates NarL and NarP by phosphorylation.  NarQ probably negatively regulates the NarL protein by dephosphorylation.
What are the official names of this protein?
Nitrate/nitrite sensor protein NarQ.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PUFX_CERS4
Sequence: MADKTIFNDHLNTNPKTNLRLWVAFQMMKGAGWAGGVFFGTLLLIGFFRVVGRMLPIQENQAPAPNITGALETGIELIKHLV
What is the function of this protein?
Associated with the reaction center - light-harvesting complex I.  May play a critical role in facilitating the interaction between this complex and other components required for light-driven cyclic electron transfer.
What are the official names of this protein?
Intrinsic membrane protein PufX.
What is the protein family that this protein belongs to?
Belongs to the PufX family.
What are the subcellular locations of this protein?
Cell membrane.
Protein: DPO4_CAUVC
Sequence: MARCPACASPRTVFHEELGTLSIAHMDCDAFYASVEKRDDPSLRDLPVIIGGGKRGVVTTACYIARMSGAKSAMPMFKALKLCPDAVVIKPNFAKYKEESRRIHEKLDRLTPLIQPLSLDEAWIDLTGTERLHGATPAQMLARLQAEIERDIGLTVSVGLAPNKFLAKIASELDKPRGFSAIGAAEAQSFLANKPVNILPGVGPATVASLAEIGLRTVGDIAAADLKLLANRLGSGGMRLHRLAHGQDSRIVDPDQARKTISAETTFNDDLHKREDLEDELWPLCEKVAKQARQEGVAGRVATLKLRTPDFKIHTRRRTLAVPTQTARTLFQVARELLSAEPRGLAYRLIGAGLTEFVDADTAGADMFADEERRALKSETAIDALRGKFGAAAVVTGRALKGR
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBA_LIRTU
Sequence: MTAILERRESTSLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYRFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAAVEAPSTNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: Y1581_LISW6
Sequence: MFTESMLFLLLFLLLGLIAKNNSLIIAVAVVILLKLFHVDGKVMEMVQAKGINWGVTIITVAILIPIATGQIGFKDLIDSFKSAAGWIGLGAGIAVSILAKKGVSYMAVDPQVTVSLVFGTILAVVLFRGIAAGPVIAAGIAYMAMQLVAFIK
What are the official names of this protein?
UPF0756 membrane protein lwe1581.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LELP1_MACFA
Sequence: MSSDDKSKSNDPKTEPKNCDPKCEQKCESKCQPSCLKKLLQRCSEKCPREKCPAPPKCPPCPSPSPSSCPPKPCAKPCPPKCPSSCPPPCPPPE
What are the official names of this protein?
Late cornified envelope-like proline-rich protein 1.
What is the protein family that this protein belongs to?
Belongs to the cornifin (SPRR) family.
Protein: ARL5C_MOUSE
Sequence: MGQLIAKLMRIFGSQEHKVIIVGLDNAGKTTILYQFLTNEVVHTCSTIGSNVEEIVLRKTHFLMWDLGGQEALRSTWDTYYSNAEFVILVIDSTDRNRLLTTREELYKMLAHEALQNASVLIFANKQDVKDSMTTAEISQFLTLSAIKDHPWHIQGCCALTGEGLPAGLQWMQAQATAN
What is the function of this protein?
Binds and exchanges GTP and GDP.
What are the official names of this protein?
ADP-ribosylation factor-like protein 5C, ADP-ribosylation factor-like protein 12.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
Protein: IDUA_CANLF
Sequence: MRPPGPRAPGLALLAALLAAPRALAEAPHLVLVDAARALRPLRPFWRSTGFCPPLPHSQADRYDLSWDQQLNLAYVGAVPHGGIEQVRTHWLLELITARESAGQGLSYNFTHLDGYLDLLRENQLLPGFELMGSPSQRFTDFEDKRQVLAWKELVSLLARRYIGRYGLSYVSKWNFETWNEPDHHDFDNVTMTLQGFLNYYDACSEGLRAASPALRFGGPGDSFHPWPRSPLCWGLLEHCHNGTNFFTGELGVRLDYISLHKKGAGSSIYILEQEQATVQQIRRLFPKFADTPVYNDEADPLVGWALPQPWRADVTYAAMVVKVVAQHQNPPRANGSAALRPALLSNDNAFLSFHPHPFTQRTLTARFQVNDTEPPHVQLLRKPVLTAMALLALLDGRQLWAEVSRGGTVLDSNHTVGVLASAHLPAGPRDAWRATVLLYASDDTRAHAARAVPVTLRLLGVPRGPGLVYVTLALDNPRCSPHGEWQRLGRPVFPTAEEFRRMRAAEDPVAEAPRPFPASGRLTLSVELRLPSLLLLHVCARPEKPPGPVTRLRALPLTRGQVLLVWSDERVGSKCLWTYEIQFSADGEVYTPISRKPSTFNLFVFSPESAVTSGSYRVRAVDYWARPGPFSTRVHYVEVPAPSGPPRPSDCERC
What are the official names of this protein?
Alpha-L-iduronidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 39 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: TRIM5_SAGOE
Sequence: MASRILVNIKEEVTCPICLELLTEPLSLDCGHSFCQACITANHKESTPHQGERSCPLCRMSYPSENLRPNRHLANIVERLKEVMLSPEKGQKVGHCARHGEKLLLFCEQDGNVICWLCERSQEHRGHHTFLVEEVAEKYQEKLQVALEMMRQKQQDAEKLEADVREEQASWKIQIRNDKTNIMAEFKQLRDILDCEESKELQNLEKEEKNILKRLVQSESDMALQTQSMRVLISDLERRLQGSVLELLQGVDDVIKRIETVTLQKPKTFLNEKRRVFRAPDLKGMLQAFKELTEVQRYWAHVTLVPSHPSYTVISEDERQVRYQFPIHQPSVKVNYFYGVLGSPSITSGKHYWEVDVSNKRAWILGVCVSLKYNAKWNVLRPENYQPKNGYWVIGLQNTNNYSAFQDAVKYSDFQIGSRSTASVPLIVPLFMTICPNRVGVFLDYEACTVSFFNVTNNGFLIYKFSNCHFSYPVFPYFSPVTCELPMTLCSPSS
What is the function of this protein?
Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses.  Blocks viral replication early in the life cycle, after viral entry but before reverse transcription.  In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice.  Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1-UBE2N (also known as UBC13-UEV1A complex) generates 'Lys-63'-linked polyubiquitin chains, which in turn are catalysts in the autophosphorylation of the MAP3K7/TAK1 complex (includes TAK1, TAB2, and TAB3).  Activation of the MAP3K7/TAK1 complex by autophosphorylation results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genes, thereby leading to an innate immune response in the infected cell.  Plays a role in regulating autophagy through activation of autophagy regulator BECN1 by causing its dissociation from its inhibitors BCL2 and TAB2.
What are the official names of this protein?
Tripartite motif-containing protein 5, RING-type E3 ubiquitin transferase TRIM5, TRIM5alpha.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly localizes in cytoplasmic bodies. Localization may be influenced by the coexpression of other TRIM proteins, hence partial nuclear localization is observed in the presence of TRIM22 or TRIM27. In cytoplasmic bodies, colocalizes with proteasomal subunits and SQSTM1.
Protein: AN34B_HUMAN
Sequence: MDEGMEISSEGNSLIKAVHQSRLRLTRLLLEGGAYINESNDRGETPLMIACKTKHVDHQSVSKAKMVKYLLENNADPNIQDKSGKTALMHACLEKAGPEVVSLLLKSGADLSLQDHSSYSALVYAINSEDTETLKVLLSACKAKGKEVIIITTAKLPCGKHTTKQYLNMPPVDIDGCHSPATCTTPSEIDIKTASSPLSHSSETELTLFGFKDLELAGSNDDTWDPGSPVRKPALAPKGPKLPHAPPWVKSPPLLMHQNRVASLQEELQDITPEEELSYKTNGLALSKRFITRHQSIDVKDTAHLLRAFDQASSRKMSYDEINCQSYLSEGNQQCIEVPVDQDPDSNQTIFASTLRSIVQKRNLGANHYSSDSQLSAGLTPPTSEDGKALIGKKKILSPSPSQLSESKELLENIPPGPLSRRNHAVLERRGSGAFPLDHSVTQTRQGFLPPLNVNSHPPISDINVNNKICSLLSCGQKVLMPTVPIFPKEFKSKKMLLRRQSLQTEQIKQLVNF
What are the official names of this protein?
Ankyrin repeat domain-containing protein 34B.
What is the protein family that this protein belongs to?
Belongs to the ANKRD34 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: EFEB_ECO57
Sequence: MQYEDKNGVNEPSRRRLLKGIGALALAGSCPVAHAQKTQSAPGTLSPVARNEKQPFYGEHQAGILTPQQAAMMLVAFDVLASDKADLERLFRLLTQRFAFLTQGGAAPETPNPRLPPLDSGILGGYIAPDNLTITLSVGHSLFDERFGLAPQMPKKLQKMTRFPNDSLDAALCHGDVLLQICANTQDTVIHALRDIIKHTPDLLSVRWKREGFISDHAARSKGKETPINLLGFKDGTANPDSQNDKLMQKVVWVTADQQEPAWTIGGSYQAVRLIQFRVEFWDRTPLKEQQTIFGRDKQTGAPLGMQHEHDVPDYASDPEGKGIALDSHIRLANPRTAESESSLMLRRGYSYSLGVTNSGQLDMGLLFVCYQHDLEKGFLTVQKRLNGEALEEYVKPIGGGYFFALPGVKDANDYLGSALLRV
What is the function of this protein?
Involved in the recovery of exogenous heme iron.  Extracts iron from heme while preserving the protoporphyrin ring intact.  Also displays peroxidase activity on guaiacol and catechol in vitro.  The deferrochelatase activity appears to be closely related to the peroxidation activity, but the link is unclear.
What are the official names of this protein?
Deferrochelatase, Peroxidase EfeB.
What is the protein family that this protein belongs to?
Belongs to the DyP-type peroxidase family. EfeB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: PAX_I54A2
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGENLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIIVELDDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFVSPREAKKQLKKDLKSQEQCAGSLTKVSRRTSPALRILEPMWMDSNRTATLRASFLKCPKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: GSA_ALBFT
Sequence: MTLNTDNNQILFERAKRVIPGGVNSPVRAFKAVGGTPRFVKRAQGAYFWDANNQRYTDFIGSWGPMILGHGHPAVVEAVQAAVLEGFSYGAPTEREVELAEEILRLVPSMDMVRLVSSGTEAAMSTIRLARGATGRSKLIKFEGCYHGHADALLVKAGSGLATFGNPTSAGVPPEVVQHTVVLEYNNIEQLEEAFAMQGSEIACLMMEPICGNMNFVRASVPFVKRCRELCTQYGALLVFDEVMTGFRVALGGAQSVYAKEIPGFEPDMTVMGKVIGGGMPLAAFGAKRAVMEHLAPLGTVYQAGTLSGNPVATACGLATLREISKPGFYESLARTTRSLTDGLKAAATAEGLAFSADSEGGMFGFFLLDTLPQNYVQVMKSDSARFNQLFHGLLDRGVYIAPALYEAGFVSAAHTAEDIAATVAAARAVFKIISK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRK1_DICDI
Sequence: MSTKTNIQKDWEQREFIEDMSINIQKIVEFLNKFELSTRNKLSDLNEKLTILDRQVDYLEATFKTVQE
What is the function of this protein?
Involved in regulation of actin and microtubule organization.
What are the official names of this protein?
Protein BRICK1.
What is the protein family that this protein belongs to?
Belongs to the BRK1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: AHR_MUSSP
Sequence: MSSGANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSTPADRNGGQDQCRAQIRDWQNLQEGEFLLQALNGFVLVVTADALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPSQCTDSAQGVDEAHGPPQAAVYYTPDQLPPENASFMERCFRCRLRCLLDNSSGFLAMNFQGRLKYLHGQNKKGKDGALLPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGCDAKGQLILGYTEVELCTRGSGYQFIHAADMLHCAESHIRMIKTGESGMTVFRLLAKHSRWRWVQSNARLIYRNGRPDYIIATQRPLTDEEGREHLQKRSMSLPFMFATGEAVLYEISSPFSPIMDPLPIRTKSNTSRKDWAPQSTPSKDSFHPSSLMSALIQQDESIYLCPPSSPAPLDSHFLMGSVSKCGSWQDSFAATGSEAALKHEQIGHAQDVNLALSGGPSELFPDNKNNDLYSIMRDLGIDFEDIRSMQNEEFFRTDSTAAAAGEVDFKDIDITDEILTYVQDSLNNSTLLNSACQQQPVTQHLSCMLQERLQLEQQQQLQQPPPQALEPQQQLCQMVCPQQDLGPKHTQINGTFASWNPTPPVSFNCPQQELKHYQIFSSLQGTAQEFPYKPEVDSVPYTQNFAPCNQPLLPEHSKSVQLDFPGRDFEPSLHPTTSNLDFVSCLQVPENQSHGINSQSAMVSPQAYYAGAMSMYQCQPGPQRTPVDQTQYGSEIPGSQAFLSKVQSRGVFNETYSSDLSSIGHAAQTTGHLHHLAEARPLPDITPGGFL
What is the function of this protein?
Ligand-activated transcription factor that enables cells to adapt to changing conditions by sensing compounds from the environment, diet, microbiome and cellular metabolism, and which plays important roles in development, immunity and cancer.  Upon ligand binding, translocates into the nucleus, where it heterodimerizes with ARNT and induces transcription by binding to xenobiotic response elements (XRE).  Regulates a variety of biological processes, including angiogenesis, hematopoiesis, drug and lipid metabolism, cell motility and immune modulation.  Xenobiotics can act as ligands: upon xenobiotic-binding, activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene).  Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons.  Next to xenobiotics, natural ligands derived from plants, microbiota, and endogenous metabolism are potent AHR agonists.  Tryptophan (Trp) derivatives constitute an important class of endogenous AHR ligands.  Acts as a negative regulator of anti-tumor immunity: indoles and kynurenic acid generated by Trp catabolism act as ligand and activate AHR, thereby promoting AHR-driven cancer cell motility and suppressing adaptive immunity.  Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1.  Inhibits PER1 by repressing the CLOCK-BMAL1 heterodimer mediated transcriptional activation of PER1.  The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription.
What are the official names of this protein?
Aryl hydrocarbon receptor, Ah receptor, AhR.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus.
Protein: DEF1B_SOLLC
Sequence: MAMAAASWASSSSFTRFLRPLLSRNSSPSPISYSLHRYKSANCLFFSASSNKPPKLAVYAQARRVLSSKTKGDEIATPADLSFVVPLKIVEYPDPILRAKNKRIDNFDANLKKLVDEMFDIMYKTDGIGLSAPQVGMNVQLMVFNAAGERGEGEEIVLVNPRVSRYSRRIIPYEEGCLSFPMIHGDVKRPESVKVDAQDINGTRFEISLSALPARVFQHEFDHLQGVLFFDKMTDEVLDTIREKLVALEKKYEDRTGLPTPESINTRKIKKAAVGFGKS
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.
What are the official names of this protein?
Peptide deformylase 1B, chloroplastic, PDF 1B, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CYSC_AERS4
Sequence: MSNIVWHQHAVSKQSRSELKGQKPLVIWFTGLSGAGKSTLAGALEQALAVEGKHTYLLDGDNVRHGLCGDLGFDDAARQENIRRVGEVAKLMVDAGLIVLTAFISPFRAERELVRNLLGADEFVEVFVDAPLAVCEERDPKGLYKKARAGEIRNFTGIDSAYEAPKQPEIHLLNAGKPVAALVDELLTALRQGNYL
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: RBL19_ARATH
Sequence: MSSPGTSMFTNFTKLCKGLALVLVVGHLVVQFIPATVPYLALIPARTIPFAWNLITSGYFELSVYGVVFSTVSLLFMGKFLEPVWGSTEFLKFIFVVNFLTYLCVFVTAIALYYITRLEVYLYMPFAGFHGVLAGLLVGIKQIIPDQEILLLKIKAKWLPSIMLILSIASSFFTLDSAAYLPTLIFGTYMGWLYLRYLQRRPETKLRGDPSDDFAFSTFFPELLRPVIDPIALIFHRMLCGRSNATSEDHDYSTSGAPLPGSDSAEASRRRERGARALEERLGTERLVPARNKDELQSDGLDNV
What is the function of this protein?
Probable rhomboid-type serine protease that catalyzes intramembrane proteolysis.
What are the official names of this protein?
Rhomboid-like protein 19, AtRBL19.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS10_ENT38
Sequence: MQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTILISPHVNKDARDQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: NECP1_BOVIN
Sequence: MASELEYESVLCVKPDVSVYRIPPRASNRGYRASDWKLDQPDWTGRLRITSKGKVAYIKLEDKVSGELFAQAPVEQYPGIAVETVTDSSRYFVIRIQDGTGRSAFIGIGFSDRGDAFDFNVSLQDHFKWVKQESEISKESQEMDSRPKLDLGFKEGQTIKLSIGNITTKKGGTSKPKTAGTGGLSLLPPPPGGKVTIPPPSSSVAISNHVTPPPIPKSNHGGSDADILLDLDSPAPITTPAPAPVSASNDLWGDFSTASSSVPNQAPQPSNWVQF
What is the function of this protein?
Involved in endocytosis.
What are the official names of this protein?
Adaptin ear-binding coat-associated protein 1, NECAP endocytosis-associated protein 1, NECAP-1.
What is the protein family that this protein belongs to?
Belongs to the NECAP family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, clathrin-coated vesicle membrane. Cell membrane. Note=Colocalizes with AP-2 at the plasma membrane.
Protein: RL21_RHIEC
Sequence: MFAVIKTGGKQYRVAANDVLTIEKLEASAGDSIEFTEVLVIGEGADAAIGAPFVAGASVKAEVVDQTRGKKVIAFKKRRRQNSKRSRGHRQHHTVVRITDIVAAK
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.