PharMolix/UniProtQA huggingface dataset:
Protein: UPPP2_RHILO
Sequence: MQGITELLPISSTAHMRIVPALLGWQDPGSAFSAAMQLAALAAVISYFWGDVRDLLFGSLDALTRRDFSDRHFRLASWIVLATIPIVIAGVALSGVLNACNSPLRSLTVIGWSCIAMAILLALAEIFARHKRTIAEASLADALLVGVAQIGALIPGVSRSGSTLTAALGLGFKRAEAARFSFLLGLPAIALAGLKELWELHKVHLDAHGWSVLATGLVVASISAFFAIWGLMRVLERFSAWPFVIYRGLLGVVLLLGLAMGWLA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase 2, Bacitracin resistance protein 2, Undecaprenyl pyrophosphate phosphatase 2.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FMT_METNO
Sequence: MPLKVVFMGTPDFAVPTLAEIVGSGHEVVAVYTRAPAPAGRGMALRPSPVQALAERFGLPVRTPATLRSEEAVEIFRGHDADVAVVVAYGMILPPAILDAPRLGCLNLHASILPRWRGAAPIQRAVMAGDSETGVAVMRMEPGLDTGPVAMLERVAITPEMTAGELHDRLMPLGADLMNRALGALERGGLTFTPQAAEGIVYAHKITNEEARLDWAEPAQRLHDTIRGLSPFPGAFFMADLGRGPERVKVLRASLADGRAEPGTLLDAHGTVACGEGAIRLLRVQPAGKGPMEAGDFLRGRRLEPGARLA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RL22_METPB
Sequence: MGKPATPRALPENEAKAVARMLRVSPQKLNLVAALIRGKKVDTALADLEFSRKRIARDVKKCLESAIANAENNHDLDVDDLVVSQAFVGKALVLKRFHARARGRGARILKPFSNLTIVVREVRAEAA
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: DDL_ACTSZ
Sequence: MKSLKQQKIAVLLGGTASEREVSLNSGAAVLDALRSQGYDAHPVDPKDMPVADLKQQGFERVFNILHGRGGEDGVIQGVLEQIGLPYTGCGVMTSALTMDKMRTKMLWKGFGLPIADMEIVTKNTALSLEPQAIVARLGLPLMVKPSREGSSVGLTKVDSADKLKSAVDLALKFDDIVLIEEWLSGDELTVPVLGDEVLPAVQIVPEGEFYDYNAKYISDNTRYICPMPMSDERWDELKNLVKRAYEAVGCRGWSRIDVMTDSEGNFRLIEVNTTPGMTSHSLFPKSAATVGYSFEKLVEKILELSV
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_CAMJD
Sequence: MKELVNILDFLPEELGEKIKPMFRVKQIYQWIYQKYANNFSDMSSLPKDLRLELAQNFHFSPVKCVKNEQSKDGSIKYLFELIDGLRVESVLLPMKEEKIDTEGKRISHARYTICVSSQVGCKSSCSFCLTAKGGLKRNLSAGEIVGQILWIKKQNNIPYERRVNIVYMGMGEPLDNLKNVSKAVKILAQNDGLAISPRRQTISTSGLAKQIKELGQMNLGVLLAISLHAVNDELRTELMPINKAYNIAAIMDAVREFPIDQRKRVMFEYLLIDGINDKLEHAKELVKLLNGIKAKVNLILFNPHEGSLYKRPSLENAIKFQDLLSSKGVTCTIRESKGLDISAACGQLKERAKEQ
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP9P_CTFVL
Sequence: MFGYLQLINPTTDIYIKDYGNFSGIVAHQAYDPVRRDHMLLRSMKLHFGPNSKLLWLGDFHAITLSHANMIFGASSVGFKGVNVSTLPPDTLTTGIRPRPVVTMDFAQLKGFYSDLAQKEDYIMYFHDMVKFVSQTGGAPVSLRDVFLWISESVTGPVVIRTDCVTGCNNLWPSGSGHFYFPYERKTKFRYGTFVECGKNLTWSEGPQWDVKSYVVGFNFVTRANSLLGGGFDEVCYRLMMQAEVPRQVAEQGLTLEQAVRKLASEHHMSRPQLTSRRVPGITDQTKYEAYVVCGPFRTGQVVADSLQMAEDLAWREMLGTLKTLIHDEARQTKGCCXRCWPGELYLINIESAGFREGASAAAAYQAGFLRAFYGCLNTSVCSFSSLDDGLRWLCTRLSTKSIGAKGRTVVLFGCHSEGEVLADGFGKTYSAAEAREQVALSGKIGGSAQVIVVWQRCRESKLQRLLPELAMVSYVPEEVVAGFKRVRELETYPQWCLWLYRSMIESMGGIDVGVRDASPLTESGVVYQVEAAQYGMRTTRVRRADGTLDYQGLSWTSLLMLLLGHYGADQTYEALRVSSMFIRAREVGWRKRGTFSCIVST
What are the official names of this protein?
Non structural protein VP9'.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: YCF4_SYNY3
Sequence: MGGQTLAESSQVLRQEVLGARRFSNFFWAGISTIGGVGFLLAGLSSYFGKNLLIVSDTTGLQFIPQGVALLFYGVAGSTVAGYLWLTMALNVGSGYNEFNKKSGQVTIFRWGFPGKNRRIELINKIADVQAVKAEIKEGVNPKRSLYLKVKQRRDIPLTRAGQPISLSQLENQGAELARFLGVPLEGL
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RS19_PELPB
Sequence: MPRSLKKGPFIDIKLEKRILDMNSKGEKKVIKTWSRSSMISPDFVGHTVAVHNGKNHVPVYVGDNMVGHKLGEFAPTRSFRGHAGGGKAEKGGSAPRKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: Y1013_PHOPR
Sequence: MKKCVLLTSLAIMTFATIGVQAATLSTSKNIELLVVDGKKVESSYWSPTESVELADGKHQIVVRFDGEVKNGSKNTIYTTRPYLFDLNVADKDAKIVLPTLTTLSQTTAYFDRGADWALEYTDGSKEVLKTVELKGDGFGSFSNMEKLVAKYNSKHGIVFEQGYAVDLQEVAVKVDEQGKVQITGDSLTQLKMWYTKASAKEKKAFKIWAAEHDFN
What are the official names of this protein?
UPF0319 protein PBPRA1013, ORF2.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: EXPA8_ARATH
Sequence: MYTPSYLKYSIISIISVLFLQGTHGDDGGWQGGHATFYGGEDASGTMGGACGYGNLYGQGYGTNTAALSTALFNNGLTCGACYEMKCNDDPRWCLGSTITVTATNFCPPNPGLSNDNGGWCNPPLQHFDLAEPAFLQIAQYRAGIVPVSFRRVPCMKKGGIRFTINGHSYFNLVLISNVGGAGDVHAVSIKGSKTQSWQAMSRNWGQNWQSNSYMNDQSLSFQVTTSDGRTLVSNDVAPSNWQFGQTYQGGQF
What is the function of this protein?
Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.  No enzymatic activity has been found (By similarity).
What are the official names of this protein?
Expansin-A8, AtEXPA8, Alpha-expansin-8, At-EXP8, AtEx8, Ath-ExpAlpha-1.11.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin A subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: RS11_STAAC
Sequence: MARKQVSRKRRVKKNIENGVAHIRSTFNNTIVTITDEFGNALSWSSAGALGFKGSKKSTPFAAQMASETASKSAMEHGLKTVEVTVKGPGPGRESAIRALQSAGLEVTAIRDVTPVPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: DTD_RUBXD
Sequence: MRVVLQRVKSASVTVEGETVASIGEGLLLLVGVGREDGEAEAGWLAEKVASLRIFGDEQGKMNLSVRDVGGEVLAVSQFTLLADTRKGNRPSFIRAADPERAEPLFEYFCERLREAGVSSVKTGVFGAVMDVALVNAGPVTIVLER
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_BIFAA
Sequence: MSVEVTNETAWQIDGKIFSDLGVWVMSQMRVSTQSDLTIMFVDPDPIAQLHMRWMNLEGPTDVMSFPMDELRPGDGGTEMEGVLGDIVLCPWVAAQQALAAGHSTMEEMMLLTIHGILHLLGYDHVTPEQERQMFGLQRQLLLTFFALRQGAGARATLPAGTPDALAEWDREHAAGGKTAK
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_ACET2
Sequence: MKEQLNSIRVQAEQELSNVGTIAELENIRVKYLGKKGELTAVLRGMGSLSPEERPVIGQLANEIRAYIESRIEEARNELIKKERSQKLEREVIDVTMPGKRKMLGKKHPLSIVIDEIKDVFIGMGYEIAEGPEVELDYYNFEALNIPRNHPARDVQDTFYINNNILLRTQTSPVQIRVMENKKPPIKIICPGRVYRSDAVDATHSPIFHQVEGLVVDKGVTMGDLVGTLRVFAKSLFGEKTEIRLRPHHFPFTEPSAEVDVSCWACGGTGCRICKNEGWIEILGAGMVHPKVLEVCGIDPEVYSGFAFGLGVERTAMGRFNIDDMRLLYENDIRFLKQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM5_CANAL
Sequence: MSKFSPPINRNMVELDRSFFHKEVPLLAAYFPNPKFLGQFVKSCQNDILYVQTVKHIISMDDSKAILLRDDVKSISDLNPETQLKINEFGIILKPYTLKLDYSFWKSEEILKSILPENLIDDVPSGFSQAGHLAHINLRDEYKPFGKLIGQVILDKNPSVLTVVDKVNTIANKFRTFPLELLAGEPNYIVEQSESGCKFKFDFSKVYWNSRLSTEHERIIGKFNSGDVVGDVFGGVGPFAIPASKKNVIVLANDLNPESYKYLQENIKINKVEPFIKPFNLDGREFIRKAPELLLQWHNSQNGIIEKKIIKKVSIDDNKTKKNFERKPIIETTKIPKFYHHFVMNLPDSALTFLDEFIGLYGSNPQLKTDPEFKLPIIHVHCFEKFENNENPTPEELHNRVYEKICKLIQFPLNKEKMEFHEVRMVSPTKPMFCVSFELPEEVAFKQSK
What is the function of this protein?
Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs.  Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside.  This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
What are the official names of this protein?
tRNA (guanine(37)-N1)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase, tRNA methyltransferase 5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Protein: LCK_RAT
Sequence: MGCVCSSNPEDDWMENIDVCENCHYPIVPLDSKSTLPIRTGSEVRDPLVTYEGSLPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHDLVRHYTNASDGLCTKLSRPCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHPRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLNVNKLLDMAAQIAEGMAFIEEQNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLEKGYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLRSVLDDFFTATEGQYQPQP
What is the function of this protein?
Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells.  Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways.  Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors.  Association of the TCR with a peptide antigen-bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molecules, respectively, thereby recruiting the associated LCK protein to the vicinity of the TCR/CD3 complex.  LCK then phosphorylates tyrosine residues within the immunoreceptor tyrosine-based activation motifs (ITAM) of the cytoplasmic tails of the TCR-gamma chains and CD3 subunits, initiating the TCR/CD3 signaling pathway.  Once stimulated, the TCR recruits the tyrosine kinase ZAP70, that becomes phosphorylated and activated by LCK.  Following this, a large number of signaling molecules are recruited, ultimately leading to lymphokine production.  LCK also contributes to signaling by other receptor molecules.  Associates directly with the cytoplasmic tail of CD2, which leads to hyperphosphorylation and activation of LCK.  Also plays a role in the IL2 receptor-linked signaling pathway that controls the T-cell proliferative response.  Binding of IL2 to its receptor results in increased activity of LCK.  Is expressed at all stages of thymocyte development and is required for the regulation of maturation events that are governed by both pre-TCR and mature alpha beta TCR.  Phosphorylates other substrates including RUNX3, PTK2B/PYK2, the microtubule-associated protein MAPT, RHOH or TYROBP (By similarity).  Interacts with UNC119; this interaction plays a crucial role in activation of LCK (By similarity).
What are the official names of this protein?
Proto-oncogene tyrosine-protein kinase LCK, Lymphocyte cell-specific protein-tyrosine kinase, p56-LCK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytosol. Note=Present in lipid rafts in an inactive form.
Protein: UVRB_CHLMU
Sequence: MTHYHNPLNGRKVLNQQFVLQAPFLPCGDQPEAIRQLSRGILDGIPSQVLLGTTGSGKTFTMANVIANVNVPTLVLAHNKTLAAQLYQEFKAFFPENAVEYFISYYDYYQPEAYIARSDTYIEKSLLINDEIDKLRLSATRSILERRDTLIVSSISCIYGIGSPDNYSSMALILEVGKEYPRSQLSAQLVRMHYQASASPQRSAFRERGSVIDIFLAYESDLAVRLEFVNDTLVSIEYTDPLTMIPSHTVPSVTLYPGSHYVTPEAVREQAIRTIREELEQRLLFFEGRPVEQERLFQRTTHDIEMIKEIGFCKGIENYSRHFTGAAPGEPPTCLLDYFPEDFLLIIDESHQTLPQLRAMYRGDQSRKQSLVEYGFRLPSAFDNRPLTYEEARRYFRRVVYVSATPGELEVQESRGHIIEQIIRPTGIPDPLPEIRPATGQIDDLLEEIRQRLRKDQEKILVVSVTKKLAEDIAAFLAELGIAAAYLHSGIETAERTQILTDLRLGTIDVLIGVNLLREGIDLPEVSLVAILDADKEGFLRSSASLIQFCGRAARNVHGKVIFYADRITPSMDHMLKETERRRQIQLDYNKKHNITPKPIIKPILANPITKEGAQEDSRPETQSTEDLESSIKQYEEAMYKAAQDFQFDEAAKYRDLMNAAKRQLLFKQGEDGNSK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_PYRIL
Sequence: MVMLDLLSNALIQIKNAEIMGKKQVVIWPVNKLIYHTLRVLQRYGYVGEIEYIDDGRGGKYVVQLLGKINDIGPIRPRYPVKYREIVQWEQKFLPARQIGILVISTSQGVMSHIEAKERKIGGVLLAYVY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: LBD9_ARATH
Sequence: MDVSRVNVKRAPCALCTTKNKRCPKKCDFAPYFPAERKGEYENAHKLFGTSNIIKMMRFASKDKQRDMLASSILMEGDAWKKDPARGGFGMIQKLKWQIELRKIYLNELKEKIKVEKEKTELRL
What are the official names of this protein?
LOB domain-containing protein 9, ASYMMETRIC LEAVES 2-like protein 35, AS2-like protein 35.
What is the protein family that this protein belongs to?
Belongs to the LOB domain-containing protein family.
Protein: YMDB_CROTZ
Sequence: MSGRINVVQGDITRIDTDVIVNAANPSLMGGGGVDGAIHRAAGPSLLAACKVVRQQQGECQPGHAVITEAGDLAAKAVIHTVGPIWRGGHDNEPQLLADAYRNSLELVTANGYNSVAFPAISTGIYGYPKAAAAQIAFETVSDYLTRRPQPKQVYFVCYDEENFLLYQRLLGQYDE
What is the function of this protein?
Deacetylates O-acetyl-ADP ribose to yield ADP-ribose and free acetate.  Down-regulates ribonuclease 3 (RNase III) activity.  Acts by interacting directly with the region of the ribonuclease that is required for dimerization/activation.
What are the official names of this protein?
O-acetyl-ADP-ribose deacetylase, Regulator of RNase III activity.
What is the protein family that this protein belongs to?
Belongs to the YmdB family.
Protein: MUTL_BORGP
Sequence: MNKIRFLDKYLVQKIAAGESIDRPCSILRELLDNSIDSGATKIEVFLEEGGIHKILIIDNGIGIGKEDLKICYLPHTTSKISSEEDLRKIETLGFRGEALSSIAICSNISITSSTTGNESYQIEVENGIEKCFKKQPAINGTIVNVTKIFHNFPARKRFLKQEPIETKMCLKVLEEKIITHPEINFEINLNQKLRKIYFKESLIDRVQNVYGNVIENNKFKVLKKEHENIKIELFLAPANFSKKSKRHIKTFVNRRPIDQKDLLEAITNGHSRIISPGNFPICYLFLEINPEYIDFNVHPQKKEVRFFNLPFLFKLISDNINNFFDKDINSYNEIVIKRQLTDDDNLIEMINQPKNLNKTNTYDIIQNKNLETEHTVNDLSKNIIQNDIGLRRYNSIIQNRPSFKENITNIFSDKFLEFEEPPNKNEKEEIKFNYIGQIFSEFLIVEKVNEIYFIDQHAVHEKIIYEKLRNSKKTVQKLLIPIEFTIVDKNIEEIIDSEIEEYKKMDIIISKIGPKKYQLESIPNICNQYENTLINFFQSRKSRTINSLESDLYANIACRKAVKTNDILSLEFSKFLIDEFFKLEIKHCPHGRKIYYKISKFELEKKVARA
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: TIG_BORPE
Sequence: MQPVVETLSGLERRVDLAVSVAEVEKEVQAQLKRVGRTAKVAGFRPGKAPLAMLERSHGPGIRYDVINSLVGRAFEQAVDGAKLRVAGSPTLTPKTEGVAEDTLAFTATFEVYPEVTVPDLSALAVTRYDTPVTDAEVNQTLDVLRKQRAKFEIREGRASQDGDRVVLDFAGTIDGVPFEGGKAEDFPFVLGQGRMLPEFEEAALGLKAGESKVFPLKFPDDYQGKEVAGKTAEFTITVKEVAEGVLPEVDAEFAKSLGQAEGDVEKLKADIRTNIEREVKARLQGRTKGSVMDALVEAGKFDVPKALVDSDVEGRIAAAREELKQRGVPNADSVPMPAEVFSTESERRVRLGLLVSELVKQAQLQAKPEQVRARIEEFAQNYEQPAQVVSYYLADRQRRAEIEAIVLEDNVVAHVLENAKVADEKVPFDQLMGMA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: TREA_XANAC
Sequence: MPYATARSGDVMSSAAPPCCTSLLGLSLSMFVAPGTLTAAPLDAPVVNAPAPTPPTPDLAYPELFQAVQRGELFDDQKHFVDFLPLRDPALINADYLAQHDHPGFDLRKFVDANFEESPPVQTDAIRQDTALREHIDLLWPKLVRSQNHVPPHSSLLALPHPYVVPGGRFREVYYWDSYFTMLGLVKSGETTLSRQMLDNFAYLIDTYGHIPNGNRTYYLSRSQPPFFSYMVELQAGVEGEAVYQRYLPQLQKEYAYWMQGSDDLQPGQAARHVVRLADGSVLNRYWDERDTPRPEAWLHDTRTAAEVTDRPAAEVYRDLRAGAESGWDYTSRWLADGQNLRTIRTTAILPIDLNSLLYHLERTLALACAQPGAECTRDYAALAQQRKQAIDAHLWNTAGYYADYDWQTRTLSNQVTAAALYPLFAGLASDDHAKRTASTVRKTLLRPGGLATTAVKTGQQWDEPNGWAPLQWVAVDGLRRYGEDALARTIGERFLAQVQALFAREHKLVEKYGLETDAAGGGGGEYALQDGFGWTNGVTLMLLNLYPGKDTKAAPAKRVRKPEAAAR
What is the function of this protein?
Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.
What are the official names of this protein?
Periplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: GATB_SYNE7
Sequence: MTATAPVKTEYEAVIGLETHVQLGTATKIFSNASTEFGADPNTHIDPVVLGLPGTLPVLNQKVLEYAVKAGLALNCQIAPYSKFDRKQYFYPDLPKNYQISQYDLPIAEHGWIEIEVAEKGKEPYTKKIGVTRLHMEEDAGKLVHAGSDRLAGSTHSLVDYNRAGVALAEIVSEPDLRTGKEAAEYAQELRRIMRYLGVSDGNMAEGSLRCDVNISIRPKGTEKFGTKVEIKNMNSFNAIQRAIEFEIERQIRCLETGEPIVQETRLWDEGKQVTKSMRSKEGSSDYRYFPEPDLGPIEVSETQRETWRSELPELPAQKRHRYAEQYGLSAYDARVLTDEKSTADYYEATVAAGADAKQAANWLMGDIAAYVNANKLLVSDLPLQPQDLAELVNLIEAGTISGKIAKEILPELLEKGGSPKAIVEAKGLTQISDPAQIEALVDELLAAHPTELEQFRAGKTKLQGFFVGQLMKKTGGRVDPKLSNQILNQKLKG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: RUVA_GLOC7
Sequence: MINYLKGKTTQILKTPSNRNILILEVNHIGYEIQIPSRLARNLSLEEDQIVQIFTHLQIREDQQILYGFSTDSERDLFRQLININGVGTQTAIALIDTLGIEALINAIVTNDVKTLSKTPGVGPKTAERIALELKSKLSQWEQAIALKTPVSVGVPSREILEEVEMTLLALGYTDEEIDQAISAISQDNLLLKNPHVEEWLKSAIAWLS
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: Y2935_ERWT9
Sequence: MTKQPDEWLDDVPDNDEEDEEIIWVSKSEIKRDAEELKRLGAELMELGSNSLDRIPLDEDLRSAIELAQKIKKEGRRRQMQLIGKMLRSRDEEPIRTALDKLKNRHNQQVALFHKLEMMRDRLVEQGDEAVAEVLALYPNADRQQLRAMIRNAQKEKAGNKPPKAYRQIFQYLRELAEA
What are the official names of this protein?
UPF0307 protein ETA_29350.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: RL29_HAEIE
Sequence: MKAQDLRTKSVEELNAELVNLLGEQFKLRMQTATGQLQQTHQAKQVRRDIARVKTVLTEKAGE
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: Y00B_BPT4
Sequence: MTCFKNEKGEVFRLHVNDPRIKTEKLVGVGNTVAATAKAAELEKAKPWYNKSATNPEAVKLIPNLYEWYVTKYDPDHYKRTGVAKWKSVNNITVNSKLFGRAFNEFKRGWIPDEKFYEVYNEICKN
What are the official names of this protein?
Uncharacterized 14.7 kDa protein in Gp60-mobA intergenic region.