PharMolix/UniProtQA huggingface dataset:
Protein: CEF1_YEAST
Sequence: MPPVPIYVKGGVWTNVEDQILKAAVQKYGTHQWSKVASLLQKKTARQSELRWNEYLNPKLNFTEFSKEEDAQLLDLARELPNQWRTIADMMARPAQVCVERYNRLLESEDSGGAALSTGVTDLKAGDINPNAETQMARPDNGDLEDEEKEMLAEARARLLNTQGKKATRKIRERMLEESKRIAELQKRRELKQAGINVAIKKPKKKYGTDIDYNEDIVYEQAPMPGIYDTSTEDRQIKKKFEQFERKVNRKGLDGNKDKPSKKNKDKKRKHDENEHVEKAALGESTTLTDEYKKPKLILSAPGTKQGKVTYKKKLESKRQKLIEAQATGTVLTPKELLPHDSGQEDNERSNIKSGKQLKSRIRKFLVQMFASLPSPKNDFEIVLSEDEKEEDAEIAEYEKEFENERAMNEEDNFIEPPSQNDAPRVSLVAVPLAYSTLPIPEFKNNPQSAIDNKYNLLVANAINKEPHMVPEDTVDFLKEVESRMQHITQGRTSMKIQFKTAMPPTEVLLESIQSKVESIEQLQRKLQHVQPLEQQNNEMCSTLCHHSLPALIEGQRKYYADYYAYRQEIRSLEGRRKRLQAMLNSSSSI
What is the function of this protein?
Involved in pre-mRNA splicing and cell cycle control.  Required for the binding of the NTC complex (or PRP19-associated complex) components to the spliceosome to mediate conformational rearrangement or to stabilize the structure of the spliceosome after U4 snRNA dissociation, which leads to spliceosome maturation.  Its absence leads to an arrest of the cell cycle, possibly due to the inefficient splicing of TUB1.
What are the official names of this protein?
Pre-mRNA-splicing factor CEF1, PRP nineteen-associated complex protein 85, PRP19-associated complex protein 85.
What is the protein family that this protein belongs to?
Belongs to the CEF1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: THIC_ECOBW
Sequence: MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGAHLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQTIEMGMADMSENFRARGGEIYLRKEEA
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: MURD_BURA4
Sequence: MFGDRQRPMVLVLGLGESGLAIARWCARHGCRLRIADTREAPPNLAALQAEGIDAEFVGGPFTPSLLDGGVEIVGLSPGLSPLEPALAALIAAANERAIAVWGELEFFAQALRALGTSGYQPKVLAITGTNGKTTTTNLTGLLCQRSGKKVAVAGNISPAMLDRLARAIDETALPDVWVLELSSFQLETARTFAPDAAAILNITQDHLDWHGSFDAYAAAKGRVFGATTTRVLNRDDAAVMKFAPAAGAADAARTVTFGLNEPAQQGDYGLSRDNGIAWLVEAVDRDAPDETTSRRRKRDGVHTPDIAQKRLMPADALRIRGLHNAANALAAFALARAIDLPAAPLLHALREYRGEAHRVEVIATIDDVDYVDDSKGTNVGATVAALDGLAQKIVLIAGGDGKGQDFAPLVAPVARWCRAVMLIGRDAPAIRDTLAETGVPLADHATLEAAVHAAAELAEPGDAVLLSPACASLDMFRNYAHRADVFRAAVDEIAIDKGATT
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSK_STAAM
Sequence: MAQAKKKSTAKKKTASKKRTNSRKKKNDNPIRYVIAILVVVLMVLGVFQLGIIGRLIDSFFNYLFGYSRYLTYILVLLATGFITYSKRIPKTRRTAGSIVLQIALLFVSQLVFHFNSGIKAEREPVLSYVYQSYQHSHFPNFGGGVLGFYLLELSVPLISLFGVCIITILLLCSSVILLTNHQHRDVAKVALENIKAWFGSFNEKMSERNQEKQLKREEKARLKEEQKARQNEQPQIKDVSDFTEVPQERDIPIYGHTENESKSQCQPSRKKRVFDAENSSNNIVNHQADQQEQLTEQTHNSVESENTIEEAGEVTNVSYVVPPLTLLNQPAKQKATSKAEVQRKGQVLENTLKDFGVNAKVTQIKIGPAVTQYEIQPAQGVKVSKIVNLHNDIALALAAKDVRIEAPIPGRSAVGIEVPNEKISLVSLKEVLDEKFPSNNKLEVGLGRDISGDPITVPLNEMPHLLVAGSTGSGKSVCINGIITSILLNAKPHEVKLMLIDPKMVELNVYNGIPHLLIPVVTNPHKAAQALEKIVAEMERRYDLFQHSSTRNIKGYNELIRKQNQELDEKQPELPYIVVIVDELADLMMVAGKEVENAIQRITQMARAAGIHLIVATQRPSVDVITGIIKNNIPSRIAFAVSSQTDSRTIIGTGGAEKLLGKGDMLYVGNGDSSQTRIQGAFLSDQEVQDVVNYVVEQQQANYVKEMEPDAPVDKSEMKSEDALYDEAYLFVVEQQKASTSLLQRQFRIGYNRASRLMDDLERNQVIGPQKGSKPRQVLIDLNNDEV
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Located at the septum.
Protein: T3HPD_BURCM
Sequence: MKISRSLSTVEVHTGGEAFRIVTSGLPRLPGDTIVQRRAWLKENADEIRRALMFEPRGHADMYGGYLTEPVSPTADFGVIFLHNEGYSDHCGHGVIALSTAAVELGWVQRTVPETRVGIDAPCGFIEAFVQWDGEHAGPVRFVNVPSFIWRRDVSVDTPSFGTVTGDIAYGGAFYFYVDGAPFDLPVREAAVEKLIRFGAEVKAAANAKYPVVHPEIPEINHIYGTIIANAPRHPGSTQANCCVFADREVDRSPTGSGTGGRVAQLYQRGVLAAGDTLVNESIVGTVFKGRVLRETMVGDIPAVIPEVEGSAHICGFANWIVDERDPLTYGFLVR
What is the function of this protein?
Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C).  Is likely involved in a degradation pathway that converts t3LHyp to L-proline.  Displays neither trans-4-hydroxy-L-proline (t4LHyp) epimerase nor proline racemase activity.
What are the official names of this protein?
Trans-3-hydroxy-L-proline dehydratase, T3LHyp dehydratase, t3HypD, Trans-L-3-hydroxyproline dehydratase.
What is the protein family that this protein belongs to?
Belongs to the proline racemase family.
Protein: LPXA_RHILO
Sequence: MLMKIKTSIHPSSVVEEGAQIGEGVRIGPFCHISADAVIGDGVELVSHVSVMGATTIGASTKVYPMATLGAPPQNTKHKGGRTTLVIGANCTIREGVTMHVGTDTSRGETTVGDNGNFLAYAHIAHDCVVGKNATFANGATLGGHCEIGDNVYIGGLSAVHQFVRVGDNAFLGGCSAFVGDVIPYAIAVGNRASLRGLNIIGLKRAGLPRSEIYLLRKAYRTIFDRSRTVGENIEFAKAEFASSPTAMKIIDFISSRGKRHYAVPSLKGGDGDDTDDED
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF1A_YARLI
Sequence: MGKEKTHVNLVVIGHVDAGKSTTTGHLIYKCGGIDKRTIEKFEKEADELGKGSFKYAWVLDKLKAERERGITIDIALWKFQTPKYYVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVKQLIVAINKMDSVKWSQDRYNEICKETANFVKKVGYNPKSVPFVPISGWNGDNMIEASTNCDWYKGWTKETKAGEVKGKTLLEAIDAIEPPVRPSDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKAGMVVTFAPANVTTEVKSVEMHHEILPDGGFPGDNVGFNVKNVSVKDIRRGNVAGDSKNDPPKGCDSFNAQVIVLNHPGQIGAGYAPVLDCHTAHIACKFDTLIEKIDRRTGKKMEDSPKFIKSGDAAIVKMVPSKPMCVEAFTEYPPLGRFAVRDMRQTVAVGVIKSVEKSDKAGGKVTKAAQKAAKK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPTN_PROVU
Sequence: MFSSFNVLIILRGFVRLKKWFNIDSELAFFFPKK
What are the official names of this protein?
Tryptophanase operon leader peptide.
Protein: ADT_SCHPO
Sequence: MATSSAAAAASTPVNANTITETKNSTFFFDFMMGGVSAAVSKTAAAPIERVKLLIQNQDEMIRAGRLSHRYKGIGECFKRTAAEEGVISLWRGNTANVLRYFPTQALNFAFKDKFKKMFGYKKERDGYAKWFAGNLASGGAAGAASLLFVYSLDYARTRLANDAKSAKKGGERQFNGLVDVYRKTYRSDGLRGLYRGFGPSVVGIVVYRGLYFGMYDTLKPVVLVGPLEGNFLASFLLGWAVTTGSGVASYPLDTIRRRMMMTSGEAVKYSSSFECGRQILAKEGARSFFKGAGANILRGVAGAGVLSIYDQVQLLMFGKKF
What is the function of this protein?
ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (PubMed:8675018).  Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane (By similarity).
What are the official names of this protein?
ADP,ATP carrier protein, ADP/ATP translocase, Adenine nucleotide translocator, ANT.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MQO_ACIBY
Sequence: MKKFLKYLLVLIILILIAGIVFLFRPIASKQVQTAKDEPVVDAVLVGGGIMSATLGTYFTELEPNWQIRMYERLDQVAQESSNGFNNAGTGHSGFMEMNYTEEKNGKMEIAKAEKVASQFEVAKQFWSYQVKQGVLAEPKTFINPVPHIAFVWGDNVKFLEKRYAAMIQSPLFKGMKFTEDPAVIKQWAPLVMTDRDPTQKVAATRMEVGSDVNYGSITKQLVNHLNQNPNFKLQTSTEVTGISQNDDKTWTVSFKNLKTGKTDHVKTRFVFIGAGGAAVKLLQLTGLPEAKQYAGFPVGGEFLITDNPAITAQHTAKVYGRAELGAPPMSVPHIDTRYIDGKKYVLFGPFATYSNKFLKNGSQLDLLASTNKSNVLPMTTVGLENLDLVKYLVSQVMMSDEDRLNELRKYYPDAKAEDWRLSQGGQRVQIIKKEPGKPATLQFGTEIFASKDGAVTALLGASPGASTSPYIMLNLLEKAFPQQTEGKWNQKLHEIVVSYKQDLSKDPVLLDKVRQYTSSTLGLNYTSPFKAANDETAAAPVAKAN
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: EIF3D_ASPOR
Sequence: MAPISIADIVAALPAEDTWGPATSTDNMLQGVPYAPFSKGDKLGRMADWTSESKDQRTGRQAYNRNFRDQQVYGAGSSNLFSIQAAEDESSFSVVDNTRTSAKRTFGRGGGTVFRGRAQRGAGQRGGRAGFQRVGAGRGQGDRFYDNRGGRSNRGRRFGWKDYDKPQRTREPSVNVRPDWTMLEEVDFSRLLKLNLETPDGEDVDSYGFLYYYDRSYDKAPVKGAERRLQSLDRAAYNVTTSQDPVIQELAEKDAATVFATSDILSMLMCAPRSVYSWDIVIVHQGNKIYFDKREGASLDLVTVNENAIDAPLELAESSAKQESINTPSALAMEATFINHNFALQTVAESQDAKVDMKNANPFYNASEETEPLASKAYKYRRFDLSLERDEEPLNMVVRTEVDALLKNPVNGEDQQLIVKALNEFDSKAQGSGNALDWRSKLWSQRGAVVATEMKNNSLKLARWTTQAVLAKADGMKLGFVSRANPRSAAGHVVLGVVGYKPRDLAAQMNLNLGNGWGIVRTIVDRIRALDAEEDEEKVKKYVLIKDPNRPVLRLYSVPANTFEEDEEAAAEEEEQKAEEDEE
What is the function of this protein?
mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit D, eIF3d.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCP5_ARATH
Sequence: MRSGECDEEEIQAKQERDQNQNHQVNLNHMLQQQQPSSVSSSRQWTSAFRNPRIVRVSRTFGGKDRHSKVCTVRGLRDRRIRLSVPTAIQLYDLQDRLGLSQPSKVIDWLLEAAKDDVDKLPPLQFPHGFNQMYPNLIFGNSGFGESPSSTTSTTFPGTNLGFLENWDLGGSSRTRARLTDTTTTQRESFDLDKGKWIKNDENSNQDHQGFNTNHQQQFPLTNPYNNTSAYYNLGHLQQSLDQSGNNVTVAISNVAANNNNNLNLHPPSSSAGDGSQLFFGPTPPAMSSLFPTYPSFLGASHHHHVVDGAGHLQLFSSNSNTASQQHMMPGNTSLIRPFHHLMSSNHDTDHHSSDNESDS
What is the function of this protein?
Plays a pivotal role in the control of morphogenesis of shoot organs by negatively regulating the expression of boundary-specific genes such as CUC genes, probably through the induction of miRNA (e. g.  miR164).  Participates in ovule develpment (PubMed:25378179).
What are the official names of this protein?
Transcription factor TCP5.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSGA_ACTP7
Sequence: MSKRRLTQNQQRRIKSNHHKKIAKPELEWQDEMLGEVQQGIVVTRHAKHADVETEQGEIYRCNLRRTLKNVVVGDQVSWRKGNEQLQGISGVIEAIYPRKNELSRPDYYDGIKVMAANIDQIIIVSAVLPTLSLNIIDRYLVICETAKIPALIVLNKIDLLSESERQEVQKQLAIYENIGYETLCLSADTGENMEKLDRYLSRGTSIFVGQSGVGKSSLINQLLPEVNALTGAVSDISGLGQHTTTSSRLYHLPQGGNLIDSPGIREFGLWHLEPEQITLGYREFQSVLGTCKFRDCKHKSDPGCAVREAVEKGEINAIRFENYHRLIESRDETKSQRHFRTEE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_BORPD
Sequence: MSVAEIRKSAETRMAKSLDTLKVNLSKIRTGRAHTGILDHVQVEYYGSPVPVSQVANVNLVDARTISVQPYEKPMAAAIEKAIRESDLGLNPMSLGDSIRVPMPALTEERRRDLTKVVKGEGEDAKIAVRNLRREANESLKKLVKDKEISEDDERRAQDDIQKLTDRNVTEIDKLITQKEAEIMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: L2MU_ADEG1
Sequence: MCAVAIHRSDVVMPSVLLTGGRTAKGKKRASRRRVKVPKLPKGARRKRASVTPVPTVATATASERAALTNLARRLQRGDYAAWRPADYTSPAVSEAARAAASSGTPATARDLATGTLARAVPMTGTGGRRRKRTATRRRSLKGGFLPALIPIIAAAIGAIPGIAGTAVGIANLKEQQRQFNKIYGDKK
What is the function of this protein?
The role of the precursor might be to condense the viral prochromatin for encapsidation by virtue of the two basic domains.
What are the official names of this protein?
Late L2 mu core protein, Protein X, pX, pMu.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae pX family.
What are the subcellular locations of this protein?
Virion.
Protein: HRCT1_MOUSE
Sequence: MLGLLGNTTLVCWITGTALAFLMLLWLMALCLFHRSQEHDVERNRVRQARPRLFHGRRLRLPRLVHHHHHHHVTGVTSVGVHHHHHHSPHRLHHHKHHHRHHHAHGARR
What are the official names of this protein?
Histidine-rich carboxyl terminus protein 1.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PRMA_LISMC
Sequence: MEWSEVEVHTTNEAVEPVANVLTEFGAAGVSIEDVADFLREREDKFGEIYALRREDYPEDGVIIKAYFLKTTEFVEQIPEIEQTLKNLSTFDIPLGNFQFVVNDVDDEEWATAWKKYYHPVQITDRITIVPSWESYTPSANEIIIELDPGMAFGTGTHPTTQLCIRALSDYLQPGDEVIDVGTGSGVLSIASAKLGAKSILATDLDEIATRAAEENITLNKTEHIITVKQNNLLQDINKTDVDIVVANILAEVILLFPEDVYRALKPGGIFIASGIIEDKAKVVEEALKKAGLVIEKMEQQGDWVAIISKRGVE
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DOF54_ARATH
Sequence: MQDIHDFSMNGVGGGGGGGGRFFGGGIGGGGGGDRRMRAHQNNILNHHQSLKCPRCNSLNTKFCYYNNYNLSQPRHFCKNCRRYWTKGGVLRNVPVGGGCRKAKRSKTKQVPSSSSADKPTTTQDDHHVEEKSSTGSHSSSESSSLTASNSTTVAAVSVTAAAEVASSVIPGFDMPNMKIYGNGIEWSTLLGQGSSAGGVFSEIGGFPAVSAIETTPFGFGGKFVNQDDHLKLEGETVQQQQFGDRTAQVEFQGRSSDPNMGFEPLDWGSGGGDQTLFDLTSTVDHAYWSQSQWTSSDQDQSGLYLP
What is the function of this protein?
Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence.  Enhances the DNA binding of OBF transcription factors to OCS elements (By similarity).
What are the official names of this protein?
Dof zinc finger protein DOF5.4, AtDOF5.4, OBF-binding protein 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: EF1B_SULIN
Sequence: MTDVLVVLKVFPDSDEVNLDNLYTDISNKLPKEYRIIRKETEPIAFGLNALILYVQMPEQTEGGTDNLEEVVNNIQGVSHAEVVGITRLGF
What is the function of this protein?
Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta, aEF-1beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: FTSH_CHLL3
Sequence: MAKNSLKPSNPYNSEPETPQPRPKLPMIYYVVVIALLIGLQLAFFWSGSSREIPYSTFRTFITENKVESVRIAPEKIYVTLKPGVDSGLPKQEEGNDTTRKLLPGAKTPENEVTVNPVRDESLTALLETHGVRYEGSPGTTWISELIQWVLPFALLFGLYFFIFRRMGAGGPGAQFMNIGKNKAALYENLDEHTRITFKDVAGLDEAKAEVMEVVDFLKDPKKYTRLGGKLPKGVLLVGPPGTGKTLLAKAVAGEADVPFFSISGSDFVEMFVGVGAARVRDLFRQAKEKAPCIIFIDEIDAVGRSRGKGAMMGGNDERENTLNQLLVEMDGFATDKGVILMAATNRPDVLDPALLRPGRFDRQIMVDKPDLKGRMDTFRVHTKNMSLSPDVNLKALASQTPGFAGAEIANAANEAALLASRRNKESIEMKDFEDAIERVVAGLEKKNKVINPKEKRIVAYHEAGHAIVSWMMPENDPVQKISIVPRGMSALGYTMNIPLEDRYLMTKRELFARICGLLGGRIAEESVFGEISTGAQNDLEKITGIAYNMVMVYGMSDKIGNLSYYESNNPYYGAPGVEKKFGGETARLIDEEVKAIVESAADTVRTMLKEHRSKLEALARELLTKEMLQYCQIEEILGKRPGGQEEDSGEVDCSKKSAENGMVAHEPETTADAESTEKVGLSATELAELEAAAERLRQSRNVSDN
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: PGK_PSEPF
Sequence: MTVLKMSDLDLQGKRVLIREDLNVPVKDGVVTSDARILASLPTIKLALEKGAAVMVCSHLGRPTEGEFSAENSLKPVADYLSKALGREVPLVADYLGGVDVKAGDIVLFENVRFNKGEKKNADELAQQYAALCDVFVMDAFGTAHRAEGSTHGVAKFAKVAAAGPLLAAELDALGKALGAPAKPMAAIVAGSKVSTKLDVLNSLSQICDQLIVGGGIANTFLAAAGHPVGKSLYEPDLLDTARAIAAKVSVPLPVDVVVAKEFAESAEATVKLIADVAADDMILDIGPQTAANFAELLKSSKTILWNGPVGVFEFDQFGNGTKVLAEAIAESAAFSIAGGGDTLAAIDKYGVAEKISYISTGGGAFLEFVEGKVLPAVEVLESRAKA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_DASNO
Sequence: MNENLFASFATPTMMGLPIIMLIIMFPSILFPTPKRMITNRVVSVQQWLINMIMKQMMNIHNNKGRTWTLMLISLITFIGTTNLLGLLPHTFTPTTQLSMNLGMAIPLWAGAVVTGFRHKTKASLAHFLPQGTPIPLIPMLIIIQTISLFIQPMALAVRLTANITAGHLLIHLIGGATLALMSISPTTASITFIILILLTILEFAVALIQAYVFTLLVSLYLHDNT
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: OTU7A_MOUSE
Sequence: MVSSLLPNPPSAECWAALLHDPMTLDMDAVLSDFVRSTGAEPGLARDLLEGKNWDLTAALSDYEQLRQVHTANLPHVFNEGRCAKQAERELPQPGHKVERPCLQRQDDIAQAEKRLSRGISHASSAIVSLARSHVANECNNEQFPLEMPIYTFQLPDLSVYSEDFRSFIERDLIEQATMVALEQAGRLNWWSTVCTSCKRLLPLATTGDGNCLLHAASLGMWGFHDRDLVLRKALYTMMRTGAEREALKRRWRWQQTQQNKEEEWEREWTELLKLASSEPRTHFSKNGSGTGGGVDNSEDPVYESLEEFHVFVLAHILRRPIVVVADTMLRDSGGEAFAPIPFGGIYLPLEVPPNRCHCSPLVLAYDQAHFSALVSMEQRDQQREQAVIPLTDSEHKLLPLHFAVDPGKDWEWGKDDNDNARLANLILSLEAKLNLLHSYMNVTWIRIPSETRAPLAQPESPTASAGEDVQSLAESLDSDRDSVCSNSNSNNGKNGKDKEKEKQRKDKDKTRADSVANKLGSFSKTLGIKLKKNMGGLGGLVHGKMGRANSANGKNGDSAERNKEKKSKSRKGSKEESGASASTSPSEKTTPSPTDKASGASPADKGSGSRGDAWKYSTDVKLSLNILRAAMQGERKFIFAGLLLTSHRHQFHEEMIGYYLTSAQERFSAEQEQRRRDAAAAAAAATATATVKRPARRPEAEGAPGPERASPGPTAAQPTQLVLKLKERPSPGTGASARAARAAGGAASPGPGGGARRAAPGTGGPTPGRSPPAPARQSVIHVQAAARDEACAPTVGALRPCATYPQQNRSLWSQSYSPARSALRTVNTVESLAPGGADAPGPAEHKSQTYSNGFGAARDGLEFADADAPAARSNAECGRGGPGPAQRRCQRENCAFYGRAETEHFCSYCYREELRRRREARAARP
What is the function of this protein?
Has deubiquitinating activity towards 'Lys-11'-linked polyubiquitin chains.
What are the official names of this protein?
OTU domain-containing protein 7A, Zinc finger protein Cezanne 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C64 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HIS1_ECOHS
Sequence: MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFGGCRLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMEESKQQLIDKLLTRIQGVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQQRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAND_ECOHS
Sequence: MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKAIPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_YERPP
Sequence: MKLQLVAVGTKMPDWVQTGFIEYLRRFPKDMPFELAEIPAGKRGKNADIKRILEKEGELMLAAVGKNNRIVTLDIPGTPWETPQLAQQLERWKQDGRDVSLLIGGPEGLAPACKAAAEQSWSLSPLTLPHPLVRVLVAESLYRAWSITTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_SHESM
Sequence: MSAASVSKVVVVFSGGQDSTTCLIQALTQFDEVHGITFDYGQRHREEIEVAKSLAKRLKITSHKVMDVSLLNELAISALTRDAIPVSHELMENGLPNTFVPGRNILFLTLAGIYAYQLGAEAIITGVCETDFSGYPDCRHDFVRAMESALVQGMDKKLEIITPLMWLNKAQTWALADKYQQLDLVRHHTLTCYNGIVGDGCGECPACHLRKRGLEDYLQNKAEVMASLDKATETGKPQT
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.