PharMolix/UniProtQA huggingface dataset:
Protein: COMD5_DICDI
Sequence: MIPVCQKFEQTFIKDILSLLVLYMKTKMINLVKKEEEDKLNQITESIHDKLTVSSNDNKVDPNLSSIVFTGLYYILKVALKKKVSNQIFVADITDLKLPQNLITDLTNIYNTQSKDLAERSNNDKILFPQLSSFKWRVDVIISSSFTSRVLNPVILMEMNDTNGKSKVFEVSIDNFHKLRYNAAKLLKDLEDLEQIQILSKLENK
What are the official names of this protein?
COMM domain-containing protein 5.
Protein: VATB_THENN
Sequence: MAVKEYTGLSEIRGPIVVVENVSGVRYDEVVELILENGEKRTGRVIIAGENVAIIQVFEGTEEMDIEGTRVRFLGKPLEVSLSPDLLGRTLDGLGKPRDNLGEIVPEKTVDINGSPINPSAREYPRNFIQTGISSIDVLMTLIRGQKLPIFAGNGLPYNRLAVQIARQAKVTTEEEFAVVFAAIGLRKDDANFIVRSLEESGAIKNMVVVLNLASDSVAERIATPRVALTIAEYLAFDLGMHVLVILNDMTNYCEALRELSNYRGEVPGRKGYPGYLYSDLASIYERAGIIKGRSGSITQIPILTMPNDDITHPIPDLTGYITEGQIVMSRSLFGKGIYPPIDILSSLSRLMKDGIGEGYTREDHPDVASQLFSAYSRVMEVRSIASIVGEEDLPEIDKLYLKFGEEFEHLFINQSFDEERSIEQSLDLAWKILSILPETELTRINREYIKKYYKASDET
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: DBP9_PHANO
Sequence: MAMKRKLNEHDVPEPESPQSPKRRASDASQSEPASPPAPTPAKEVVASFAELQLEPRLLRGIRDQKWGSPTAVQSKAIPLALQGRDILARSGTGTGKTGAYLLPILHNTLLRKGKTSLILVPTKELALQITKVAKALSAHCGQAVRIQNIAGKESEVVTKAKLADNPDIVIATPARASANINTGALAVTELAHLVVDEGDLVMGYGFKEDLDQIAQNIPKGVQMFLMSATLNTEVESLGSLLCNDPVVLKLDDLDKDSKRVKQYVIKCAEEEKFLLIYAMFKLGLIKGKTIVFVGDTDRSYRVKLFLEQFGIKSCVLNSELPLASRLHIVEEFNKNIYNILIASDETEILGSQKKADESRPKKKPKTDKEAKNDSGVSRGIDFLNVSCVLNFDFPATYKSYFHRIGRTARAGKSGTAISFIIPKDKYRKHKSTTFAGCENDEEVLKKVEKHQEAGQKLENYNFDMKRLEPFRYRFGDALRSVTRIAIREARIKEIRLELSKSQKLSRYFEENPEALAHLRHDQTLNHPARIQPHLKHVPDYLLPGGSRKPADVGFVGLNVPRVNKRQYVKGKGRKVVRRNGKVDPLKTFNARGKGKK
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase DBP9.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CHI1_TOBAC
Sequence: MRLCKFTALSSLLFSLLLLSASAEQCGSQAGGARCPSGLCCSKFGWCGNTNDYCGPGNCQSQCPGGPTPTPPTPPGGGDLGSIISSSMFDQMLKHRNDNACQGKGFYSYNAFINAARSFPGFGTSGDTTARKREIAAFFAQTSHETTGGWATAPDGPYAWGYCWLREQGSPGDYCTPSGQWPCAPGRKYFGRGPIQISHNYNYGPCGRAIGVDLLNNPDLVATDPVISFKSALWFWMTPQSPKPSCHDVIIGRWQPSAGDRAANRLPGFGVITNIINGGLECGRGTDSRVQDRIGFYRRYCSILGVSPGDNLDCGNQRSFGNGLLVDTM
What is the function of this protein?
Defense against chitin-containing fungal pathogens.
What are the official names of this protein?
Endochitinase A, CHN-A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family. Chitinase class I subfamily.
What are the subcellular locations of this protein?
Vacuole. Note=Vacuolar and protoplast.
Protein: MDTB_SALPA
Sequence: MQVLPPGSTGGPSRLFILRPVATTLLMAAILLAGIIGYRFLPVAALPEVDYPTIQVVTLYPGASPDVMTSSVTAPLERQFGQMSGLKQMSSQSSGGASVVTLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPIYSKVNPADPPIMTLAVTSNAMPMTQVEDMVETRVAQKISQVSGVGLVTLAGGQRPAIRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPERAVTLSANDQMQSADEYRKLIIAYQNGAPVRLGDVATVEQGAENSWLGAWANQAPAIVMNVQRQPGANIIATADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVRDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILISAVVSLTLTPMMCACMLSQQSLRKQNRFSRACERMFDRVIASYGRGLAKVLNHPWLTLSVAFATLLLSVMLWIVIPKGFFPVQDNGIIQGTLQAPQSSSYASMAQRQRQVAERILQDPAVQSLTTFVGVDGANPTLNSARLQINLKPLDARDDRVQQVISRLQTAVATIPVVALYLQPTQDLTIDTQVSRTQYQFTLQATTLDALSHWVPKLQNALQSLPQLSEVSSDWQDRGLAAWVNVDRDSASRLGISIADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTASTPGLAALETIRLTSRDGGTVSLSAIARIEQRFAPLSINHLDQFPVTTFSFNVPEGYSLGDAVQAILDTEKTLALPADITTQFQGSTLAFQAALGSTVWLIVAAVVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALIIAGSELDIIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIFQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIAMVGGLLVSQVLTLFTTPVIYLLFDRLSLYVKSRFPRHKEEA
What are the official names of this protein?
Multidrug resistance protein MdtB, Multidrug transporter MdtB.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PPME1_DEBHA
Sequence: MSGLHKQFLKKIKEQERAFGLSSLSEDPDESESNSNYFSPTPQPPNELRTDINEERHGHIRETYNDTKRDVFPIADIYTDPRSGVRFQTYFKPPSSSNAPIFICHHGAGSSSMTFCKLAQSLDNEYGKNNEYPGLFTYDMRGHGDSSTTIPPDYSLATITNDCEFIIDEFHAKHALRSSIYLLGHSLGGSVLTSYLVANPDNAYKFKGLIVLDIVEETAIKALSAMPQFVRKRPTTFGDYQEAIDWHIKESHLLHSEESALVSVPDLLRECPNGLIWKTNLQETEPFWETWFTGLSENFINCGKTQHIAKLLVLSGHETLDTNLIIGQMQGKYQLIVFNNTQNTGHFIQEDIPTQISISLVDFVRRNDSPNEYMKKEFGFVPKWGGKIHD
What is the function of this protein?
Demethylates proteins that have been reversibly carboxymethylated.  Demethylates the phosphatase PP2A catalytic subunit (By similarity).
What are the official names of this protein?
Protein phosphatase methylesterase 1, PME-1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: LGT_ZYMMO
Sequence: MPFAFIEQMKSVIHFDALGLSPIAFDLGVWHLFGLTLHPLIHWYALAYITGILLAWRYVLFLLKQPGTPMKPEQTDDLVFWSTLGILVGGRLAYVLFYQPAILENPLEIFKLWEGGMSYHGGMIGVFLAIWWVKTTNHLSWLRIADYIGCAAPIGLFLGRLANFVNGELWGRPSTMPWAVIFPQAGALPRHPSQLYEAGLEGILLFAFLNYQFFATKARLHPGKLAGFFLVGYGLSRFIVEWFREPDVQLGTLSWGLTMGQTLTIPMVIAGLWLIITSKKREISL
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PEAK3_HUMAN
Sequence: MSSPEPPTEPPEPDNPTWSTQPTYSNLGQIRAHLLPSKACRLRTPGSLSTNPEPLPPPLPKKILTRTQSLPTRRTLHPSSIQVQPPRRPFLGSHSVDKSQAAVGPACLPAELTFGPADAPLGLSLRDLHSPEAVHTALAARQLQGLRTIYARLRARLMGGHPGPCHPGHSFRLLDSSPCAESGDALYYRVVRAHEDAWHILVAKVPKPGADVPHPWGLELQASLSPHFNLQGLCGLVPEGTLPGAPWRGAVALAAEVPERTVAQWLAEACTQPPEEFVWAVALLLLQLSAALKFLEAWGAALVELRPENLLLVAPRGCATTGPPRLLLTDFGRVCLQPPGPPGSPGPHAPQLGSLLRALLSLAAPSTTPLAAGLELLAAQLTRLRPSASRTRGALQALLWGPGPELRGRGAPLGPWLRALGPWLRVRRGLLVLRLAERAAGGEAPSLEDWLCCEYLAEATESSMGQALALLWD
What is the function of this protein?
Probable catalytically inactive kinase (Probable).  Interacts with CRK-II and antagonizes CRK-II-signaling.  Prevents the formation of CRK-II-dependent membrane ruffling and lamellipodia-like extensions (PubMed:31311869).
What are the official names of this protein?
Protein PEAK3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily.
Protein: OMCB_CHLP6
Sequence: MSKLIRRVVTVLALTSMASSFASGKIEAAAAESLATRFIASTENSDDNVFQATAKKVRFGRNKNQRQEQKHTGAFCDKEFYPCEGGQCQPVDATQESCYGKMYCVRVNDDCNVEISQSVPEYATVGSPYPIEILAVGKKDCVNVVITQQLPCEVEFVSSDPATTPTSDSKLIWTIDRLGQGEKCKITVWVKPLKEGCCFTAATVCACPELRSYTKCGQPAICIKQEGPECACLRCPVCYKIEVCNTGSAIARNVVVDNPVPDGYTHASGQRVLSFNLGDMRPGDSKCFCVEFCPQKRGKVTNVATVSYCGGHKCSANVTTVVNEPCVQVNISGADWSYVCKPVEYTIVVSNPGDLKLYDVVIEDTAPSGATILEAAGAEICCNKAVWCIKEMCPGETLQFKVVAKAQSPGKFTNQVVVKTNSDCGTCTSCAEVTTHWKGLAATHMCVIDTNDPICVGENTVYRICVTNRGSAEDTNVSLILKFSKELQPVSSSGPTKGTITGNTVVFDALPKLGSKESVEFSVTLKGIAPGDARGEAILSSDTLTVPVADTENTHVY
What is the function of this protein?
In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein and the major outer membrane porin.  It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan.
What are the official names of this protein?
Large cysteine-rich periplasmic protein omcB, Large-CRP, 60 kDa cysteine-rich OMP, 60 kDa outer membrane protein, Cysteine-rich outer membrane protein.
What are the subcellular locations of this protein?
Periplasm.
Protein: NUON_RICTY
Sequence: MLLILPEITLTLIALLGQCFALMIPNKNKIIYNIVILLCIISIFLTFKYSSYEGIWHSFATGINIGISKSIVLLFTIVSLIIYRDYSNLIGEAIKFEFITLILLSIVGIFVAISSRNFLLLFCGMELTALTSYALAGFKLDDIQSSEGALKYFILGSLVTCLSLFGISFIYGFGGSIQFEDILHQLNNNSEIKPGLIIGIVLFLSSIFFKLASSPLHFWIPDVYEGSPISSITYFTSAAKIGMVIVLFNISKLIIGNYYPINYNLIKIIAILSMLFGAFGAIQQTSLKRLMAYSTILNIGYVLIGVILPNQEGYKAALLYILIYAVVSIGFFTCLIMLFGKDVDKASFKTIQGIAETHKTIAALISIVMFSMIGIPPLTGFFGKYYLFYQAINKQEFTLAYCGIFTSVVAAFYYLKVVKAMYFSKKNSIIKLPIQYGLLLINYLVLVFLLFGSFIILF
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LIPB_CLOK5
Sequence: MRKCYVKEFHKLISYSEGIEIQQKAFDFVIRNNIDGILLLLQHKPVITIGKSGGKNNILASKYELDKYSIDLCHTSRGGNVTYHGPGQLVGYPILNLNNFQKDIHLYLRQLELILINTVREYGIKAGIKPKYTGVWVGDRKIAAIGVGIRKWITRHGFAINISVNKEHFKLIVPCGIKEFGVCSLEDFTANVDYNDVVQKIENNFKMIFETDLIKEETVDNLFERSNLNLRIT
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_MARMS
Sequence: MSDDNFSRGDHSDRLLYCSFCGKSQDEVKKLIAGPSVYICNECVDLCNNIITQELSQISEDGESSDELPTPAKLSAALDDYVIGQDKAKRVLAVAVYNHYKRLRHQGKTDTSIELGKSNILLIGPTGSGKTLLAQTLARVLDVPFTIADATTLTEAGYVGEDVENIIQKLLQNCDYDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTSNILFICGGAFAGLERVISDRTEKSSIGFSATVKSKEEGRSFSEAVHRVETEDLVKFGLIPEFVGRLPVVATLSELDEEALMTILSQPKNALVKQYQHLFELEGVELEFTPESLREAAKLALERKTGARGLRSILESALLDCMYELPTRNDVVKVVMDATSIRGETAPLMVLEKEELAKNA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: COX3_HETBL
Sequence: MIRNPFHLVEYSPWPLTGSLGAMFLTVGLTSWFHNHGFITMLLGLFLVLMTMFQWWRDIIRESTFQGYHTMKVSLGMRMGMVLFITSEICFFFAFFWAYFHSSLAPNTDIGASWPPLHINPLNPFQIPLLNTAILLASGVTVTWAHHSLMGGNHAEATQSMVLTVILGGYFTLLQAEEYMEAPFSIADSVYGATFFVATGFHGLHVIIGSVFLLICLFRMLIHHFSTNHHFGFEAAAWYWHFVDVVWLILYTCIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HOX20_ORYSJ
Sequence: MRSPAALLPVVADGGGGVGVEEEMDVDEDMAMCGGRGGGGGEKKRRLSVEQVRALERSFETENKLEPERKARLARDLGLQPRQVAVWFQNRRARWKTKQLERDYAALRQSYDALRADHDALRRDKDALLAEIKELKGKLGDEDAAASFSSVKEEEDPAASDADPPATGAPQGSSESDSSAVLNDAEILPHKPAPAAAADAAASEETEAVVTGAALLHHAEVFFHGQLLKVDDDEAAFLGDDGAACGGFFADEHLPSLPWWAEPTEQWTT
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Homeobox-leucine zipper protein HOX20, HD-ZIP protein HOX20, Homeodomain transcription factor HOX20, OsHox20.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class I subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PG132_VAR67
Sequence: MDKLRVLYDEFVTISKDNLERETGLSASDVDMDFDLNIFMTLVPVLEKKVCVITPTIEDDKIVTMMKYCSYQSFSFWFLKSGAVVKSVYNKLDDAEKEKFVATFKDMLLNVQTLISLNSMYTRLRQDTEDIVSDSKKIMEIVSHLRASTTENAAYQVLQQNNSFIISTLNKILSDENYLLKIIAVFDSKLISEKETLNEYKQLYTISSESLVYGIRCVSNLDISSVQLSNNKYVLFVKKMLPKIILFQNNDINAQQFANVISKIYTLIYRQLTSNVDVGCLLTDTIESTKTKISVEKFKQTGINNVQSLIKFISDNKKEYKTIISEEYLSKEDRIITILQNIVNEHDIKYDNNLLNMRDLIVTFRERYSYKF
What is the function of this protein?
Lipid-bound viral membrane assembly protein that plays an essential role in immature virion (IV) to mature virion (MV) transition.  Functions in both crescent-shaped viral membranes formation and its enclosure to form immature virions.  In addition, participates in targeting mature virion proteins to sites of virion assembly to ensure their correct localization.
What are the official names of this protein?
Virion morphogenesis protein OPG132.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG132 family.
Protein: SPED_SALAR
Sequence: MKKLKLHGFNNLTKSLSFCIYDICYAKTAEERDGYIAYIDELYNANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPMDPKLIDQTEHPGPLPETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDIVTIDYRVRGFTRDVNGMKHFIDHEINSIQNFMSEDMKSLYDMVDVNVYQENIFHTKMLLKEFDLKHYMFHTKPEDLTETERQEITAALWKEMREIYYGRNMPAV
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: SHP1L_MOUSE
Sequence: MESDATTSEPKASVGSDSSPAEQTVLATLRDSVAAPTRGFMSPVRSVVASPRPVKGKAARRRLQLPPVTQAETCDEEPVPAVPEDQEEAQPLPPIYASPMRGMWRSEKVALYCDQVLQGSKAEDAEEAMSRYLLEKLKAKDRWLGVWKSNPELFFEKYEEASIPFVGILVEVTCKPRQNLSSCFKVTVSVAEPFSSNIANIPRDLVDEVLGELEYSAPLLEVYPVDGQDADVRDIALALEVVRFFYDFLWRDWDDEENCENYTALIEERINLWCDIQDGTIPGPIAQRFKKTLEKYKNKRVELIEYQSNIKEDPSAAEAVECWKKYYEIVMLCGLLKMWEDLRLRVHGPFFPRILRRRKGKRDFGKTITHIVAKVMTTDMVKNLSSDTLLQQHNDLNLALDSCYSGDIVVIFPGEYQASNLALLTDDITIKGVGKREEIMITSEPSHDSFVVSKADNVKLMQLSLIQQGTVDGIVVVESGHLTLENCLLKCEGTGVCVLTGASLTITNSEITGAQGAGVELYPGSIAILEGNEIHHCNNLRTSDSSKSTLGGVNMKVLPAPKLKMTNNHIYNNNGYGVSILQPSEQFFIVAEAALNKGAASGDKKDDKMLSKVMQTLNVEMNNNRIEANLKGDIRIVTG
What is the function of this protein?
Testis-specific spindle-associated factor that plays a role in spermatogenesis (PubMed:24557841).  In association with HSPA2, participates in the maintenance of spindle integrity during meiosis in male germ cells (PubMed:24557841).
What are the official names of this protein?
Testicular spindle-associated protein SHCBP1L, SHC SH2 domain-binding protein 1-like protein.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle. Note=Colocalizes with alpha tubulin during meiosis (PubMed:24557841). Colocalizes with HSPA2 at spindle during the meiosis process (PubMed:24557841).
Protein: TRMFO_SYNJA
Sequence: MPHSMSRAETLAPIHVVGGGLAGTEAAWQIAQLGVPVILSEMRPVRQSPAHHTDQLGELVCSNSFGALASDRAAGLLKEELRQLGSLVIATADRHAVPAGGALAVDRARFSQALTEAIANHPLITLRREEVTGIPEGIAVLCTGPLTSEPLAKALQAFTGLEYLSFFDASSPIVTGDSLNRAVVFQASRYDKGEAAYLNCPMTEAEYERFCQALVEAEQVPLKDFEKEERKFFEGCLPIEEMARRGKDTLRFGPLKPVGLVDPRTGSRPYAVVQLRQEDRAGKLWNLVGFQTNLKWGEQQRVFRLIPGLEAAEFVRFGVMHRNTFLNSPQLLLPTLQFRRRPTLLAAGQLVGTEGYACAVAGGWLAGQNAARLALGLPLITLPPETMMGSLFQFISSADPKHFQPMPANFGLLPELEGQKVRSKQERYARYRDRALAALAATGLVRQAQTA
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_AGARV
Sequence: MSRVGIIGAGSWGTALSLVLANNGHSVEIWSIVESEIEMLKEKHEHIDKLPGVKLPDSITFTTDIEETIKNNDILVLAVPSVFTRSTAVKMAPFVKEGQIIVCVAKGIEENTLMTISDVVESEIPCADVAVMCGPSHAEEVGRLLPTTVVAGARTQKTAEIVQDLFMNEVFRVYTSPDVLGMELGGSLKNVIALAAGMADGLGYGDNTKAALITRGIAEISVLAIEMGAKAETLFGLTGIGDLIVTCESRHSRNRKAGMLIGQGYTMDEATKEVKMVVEGIYSAKAALALAEKYDVRMPIIEEVNRVLFEDKPAKEAVSELMLRDRKIEHSSLEWK
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_BIFLS
Sequence: MAQSDITIDALDKVGRQDAEYLVSLVRSIPGFPKEGIIFRDFIPVFADPKGLRILLEALEAALPVPASEFDSIAGLESRGFLFGPALAARMGKGFIAVRKAGKLPPETIGESYDLEYGSARVEIETDAVQAGERVLIVDDLIATGGTAKAATDLIDKVGGTVAGYGFVMRLEGLDGIDKLGGKPVSSLMAMPA
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMFO_THESQ
Sequence: MIVNVIGAGLAGSEVTYNLGKRGIRVRLFEMRPKKMTEVHKTGYFAELVCSNSLKSEDITNAEGLLKAEMRLMGSITLEAAEKARVPSGKALAVDRNIFAKEVTEAVESLESVEIIREEVTEFDPEEGIWVVATGPATSDGLLPFLKKLLGDDFLFFFDAVSPIVTFESIDMERAFWGDRFGKGKDYINCPLTKEEYEEFWKALVEAEVIEMEDFDRKLLFERCQPIEEIARSGKDALRYGPLRPTGLVDPRTGKEPYAVIQLRREDKEGRFYSLVGFQTRLKWSEQKRVLRKIPCLRNAEIVRYGVMHRNVYINSPKLLDIFFRLKKHPNIFFAGQITGVEGYMESAASGIYVAYNVHRILKGLSPLKLPEETMMGALFSYIIEKVEGDLKPMYANFGLLPPLKVRVKDKFEKRKKLAERAIETMKKFLEENPW
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_METVS
Sequence: MQGVYPAIVTPFKDGSVDFEGLRKNIDFLIENGVKGVVPVGTTGESPTLTPKEHEKVIEKVVDFVNGRVEVIAGTGSNSTLEALEFSQYAEDVGADRVLLITPYYNKPPQEGLKRHFGEVANSITVPIVLYNVPSRTALNIEPDTIKYLFDEYSNITAIKEANPNLSQVSEILDICNIDVLSGNDELTLPIMSLGGKGVISVIANIAPKEFVQMVEFAEKGKFDKAKEIHYKLFPLMKLMFIETNPIPIKTAMNMLGMPSGELRLPLCEMAQSNKLKLQNALNTLGLLK
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_KLEP3
Sequence: MSTIDNLDAHTPMMQQYLKLKAQHPDILLFYRMGDFYELFYDDAKRASQLLDISLTKRGASAGEPIPMAGIPHHAVENYLAKLVNQGESVAICEQIGDPATTKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDSKGFGYATLDISSGRFRLSEPADRETMAAELQRTNPAELLYAEDFAESSLIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLVGFGVENAPRGLCAAGCLLQYVKDTQRTSLPHIRSITMERQQDSIIMDAATRRNLEITQNLAGGTDNTLASVLDCTVTPMGSRMLKRWLHMPVRDTAVLVERQQTIGALQERYTELQPVLRQVGDLERILARLALRTARPRDLARMRHALQQLPLLRELLADVDRQPVQKLREKMGEFTELRELLERSVIDAPPVLVRDGGVIAPGYSEELDEWRALADGATDYLDKLEIRERERLGLDTLKVGYNAVHGYYIQISRGQSHLAPIHYVRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKQLYDELFDLLLPHLADLQTSASALAELDVLVNLAERAETLNYCCPTFSDKPGIRISEGRHPVVEQVLKEPFIANPLQLAPQRRMLIITGPNMGGKSTYMRQTALIALLAYIGSYVPAQKVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATEHSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKMEGVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELESISPNAAATQVDGTQMSLLAAPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: MCM7_DROME
Sequence: MARRDYAQDRESIKTFLSEFCKCDDDGKKEFVYGSQLVKLAHREQVLITIDLDDLAEFNESLAEAVVDNCRRYTSIFSDVIAELLPSYKQQEVHAKDALDVYIEHRLMMESRTRNPMEQRDERNSFPSELMKRFEVGFKPLSTEKAHSIREVKAQHIGKLVTVRGIVTRCTEVKPMMVVATYTCDRCGSETYQPVNSLSFTPVHDCPSDDCRVNKAGGRLYLQTRGSKFVKFQEVKMQEHSDQVPVGHIPRSMTIMCRGEVTRMAQPGDHIVVSGVFLPLMRTGFAQMIQGLLSETFLQAHRIICINKNDEISDKDAELTPEELEELAQDDFYERLATSLAPEIYGHLDVKKALLLLLVGGVDKRPDGMKIRGNINICLMGDPGVAKSQLLGYISRLAVRSQYTTGRGSSGVGLTAAVMKDPLTGEMTLEGGALVLADQGVCCIDEFDKMADQDRTAIHEVMEQQTISIAKAGIMTTLNARVSILAAANPAFGRYNPRRTVEQNIQLPAALLSRFDLLWLIQDKPDRDNDLRLAKHITYVHSHSKQPPTRVKALDMNLMRRYINLCKRKNPTIPDELTDYIVGAYVELRREARNQKDMTFTSARNLLGILRLSTALARLRLSDSVEKDDVAEALRLLEMSKDSLNQIHEHQKGHVPNTSDRIFAIVRELAGSGKAVKISDIMDRCTTKGFKPDQVDKCIDDYEELNVWQVNMGRTKITFM
What is the function of this protein?
Acts as component of the Mcm2-7 complex (Mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells.  Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.  The active ATPase sites in the Mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit.  The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
What are the official names of this protein?
DNA replication licensing factor Mcm7, Minichromosome maintenance 7 protein, DmMCM3.
What are the subcellular locations of this protein?
Nucleus.