PharMolix/UniProtQA huggingface dataset:
Protein: TVP18_DEBHA
Sequence: MALNISSVFSNLFAGFSSDFKKKNFSLYGQWIGLLTIFLCIALGIANIFHASVVIVFSIICIVQGLVVVFVEIPFLLKICPLTDKFTTFIRNFDENWPRCGFYILMGAIQWLSLTVQVTSLIVVAVFFTLAGICYALAAFMHQEYLKTSFNVAGEPDSLEGQVGDHIVRNVL
What is the function of this protein?
Golgi membrane protein involved in vesicular trafficking.
What are the official names of this protein?
Golgi apparatus membrane protein TVP18.
What is the protein family that this protein belongs to?
Belongs to the TVP18 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: LIPB_VEREI
Sequence: MSMVVRTLGRVDYLATVQAMQDYTARRGPQDPDLLWLCEHDRLYTQGLAGQDRHVLAPGDIPVLQSNRGGQVTFHGPGQVVAYPLIDLRRAGYYVKEYVYRIEEAVIRCLAQWGVTGHRVAGAPGIYVRPDDPGGHALLPLRPPKSPGTPAPAPDFQGLGKIAALGVKVSRHCSYHGVALNVAMDLEPFARINPCGYAGLRTVDLSTIGVRLRWDEAAQLLGRQLCIWLAP
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMFO_PARMW
Sequence: MLQLLLSVERPVTVLGAGLAGTEAAWQVARAGIPVTIVEMRPMRRSPAHHSSDFAELVCSNSFGALSSDRAAGLLQEEMRRLGSLVIETADAHAVPAGGALAVDRGRYSAALTEALDQHPLVTIERREQQALPGDDQITVLATGPLTSEPLAEDLRAFTGRSDCHFFDAASPIVHGDSIDLNVAFRASRYDKGDADYINCPMDKEQYLAFREALLTAEQAELKDFDKNDATFFEGCLPIEELARRGEDTMRYGPLKPIGLWDPRWGDVNDRDVRRAKRAYAVVQLRQEDKDGRLWNLVGFQTNLKWGEQKRVLQMIPGLAEAEFVRFGVMHRNTFLESPQLLEPTLQFRSRSSLLAAGQITGTEGYAAAVAGGWLAGTNAARLARGLAPIDLPATCMSGALTHFVSEAPTAKFQPMPPNFGLLPELPERIRDKRARYGAYRDRALRDLERIKALTPNALVA
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_BIFLO
Sequence: MEGPEIKAVEAVIDNGSFGKRTLRFETGRLAQQADGAVAAYLDDDSMILSTTTAGSSPKENYDFFPLTVDVEEKMYAAGKIPGSFFRREGRPSSEAILACRIIDRPLRPLFPHTLRNEVQVVETVLAVNPDDAYDVIALNAASASTMISGLPFEGPVSGVRLALIDGQWVAFPRWSERERAVFEIVVAGRVIENGDVAIAMIEAGAGKNAWHLIYDEGQTKPDEEVVAGGLEAAKPFIKVICEAQDELKKIAAKETKEFQLFPEYTDELYARIDEIAHKDLDEALSIAEKLPRQDRIHEIKEHVREVLADEFTDMDDAEKDKELGNAFKELQRQIVRRRILTEDYRIDGRGLRDIRTLSAEVDIVPRVHGSALFQRGETQILGVTTLNMLKMEQQIDALSGPQSKRYMHNYEMPPYSTGETGRVGSPKRREIGHGALAEKALVPVLPSREEFPYAIRQVSEAIGSNGSTSMGSVCASTLSLLAAGVPLKAPVAGIAMGLVSGDVDGKHIFKTLTDILGAEDAFGDMDFKVAGTSEFITALQLDTKLDGIPADILAAALQQAKEARATILEVINECIDGPAEMSEFAPRIITTSVPVEKIGEVIGPKGKMINQIQEDTGAEIAIEDDGTVFISSEGGEAAEKAKAIIDQIANPHVPEAGETYNGKVVKTTSFGAFVNLTPGTDGLLHISQIRNLANGERIDAVEDVLKEGDTVEVIVQGVDDRGKISLAIPGFEDQENNARPSRGDRDDRRGGRGRGDRDDRRGGRGRRSERDDRDFDDRDDRPRRRRSDDFEDDYDDRPRRRRSDDRDFDRDDRDDDRPRRRRSADRDFDDRDDRDARDSRDDDRPRRRRSSDRDDRGDRDDRRGGSRGRGRGSDRNPRYATDDNYDDYRADREERTERPRRRVRRDFDPFED
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFCS_METLZ
Sequence: MDVSPEIWIEKYRPKNLAEVVGQQDVVERLRSYVATKALPHLLFTGSAGVGKTTCAVALAREMFGDTWNMNFRELNASDERGIDVVRNQIKQFARTAPLGDATFKILFLDEADALTQDAQAALRRTMENYAETCRFILSCNYSSKIIDPIQSRCAIYRFRPLTDEAISEEIARIAKKEGITIDEGAYVAITYVSLGDMRKAINALQGAAIVSDHVTAENIYAITSNAKPQEITDLLARCLEGDFETAERMLHALMYDKGIAPNELLNQLYREISRSETLDRRLKVDLIDHLGEADFRMSEGADADIQMDALLARIVRSGMN
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C small subunit, RFC small subunit, Clamp loader small subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcS subfamily.
Protein: HIS8_LISMO
Sequence: MKWKKSLAGLSSYKPGKREEEVMAELGLTKITKLSSNENPLGTSPKVAALQANSNVETEIYPDGWASSLRKEVTNFYQLEEEELIFTAGVDELIELLTRVLLDTTKNTVMATPTFVQYRQNALIEGAEVREIPLLTDGAHDLEGMLNAIDEKTTIVWICNPNNPTGNYIDLADIQAFLDKVPSDILVVLDEAYIEYVTPQPKKHEKLIRTYKNLIITRTFSKIYGLASARVGYGIADKEIINQLNIVRPPFNTTSIGQKLAIEAIKDQAFIEACRISNANGIKQYEAFAKRFEQVKLYPANGNFVLIDLGIEARTIFSYLEKNGYITRSGAALGFPTAVRITIGKEEENSAVIALLEKLL
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: TRMB_PARUW
Sequence: MKPKDLKSPFKWEHRQIVIQDRVWYVPDQHLSDIPFIFPGWTHDQTFAQDKPIYLEYCSGNGAWIASKAIEQSQYNWVGIEKKFDRTRKIWSKIKKFELDNLLTICGEGFHVTRDFFANESVDAVFINFPDPWPKKRHAKHRIVQPAFVKEIHRILKSDKLFTLVTDDAAYSKIMIDVIYQTGGFISLFEAPYYTTSYPGYGSSYFEELWREKGKSIHYHVFRKI
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: DCDB_MYCLB
Sequence: MLLSDRDLRAEITAGRFSIDPFDDTLVQPSSIDVRLDCMFRVFNNTRYTHIDPARQQDELTSLVELVDGEPFVLHPGGFVLGSTLELFTLPEDLAGRLEGKSSLGRLGLLTHSTAGFIDPGFCGHITLELSNVANLPITLWPGMKIGQLCVLRLTSPAEHPYGSASAGSKYQGQRGPTPSRSYENFIKNT
What is the function of this protein?
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
What are the official names of this protein?
dCTP deaminase, dUMP-forming, Bifunctional dCTP deaminase:dUTPase, DCD-DUT.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: HIS3_BURM7
Sequence: MNAEAKPGDWLGKVRWDANGLVPVIAQDAATNDVLMFAWMNRDALAKTIELKRAVYYSRSRQRLWFKGEESGHVQHVHEVRLDCDEDVVLLKVEQVEGIACHTGRRSCFFQKFEGTVDDGEWVAVDPVLKDPEHIYK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF4H_HUMAN
Sequence: MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRRTGPPMGSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVQKEQE
What is the function of this protein?
Stimulates the RNA helicase activity of EIF4A in the translation initiation complex.  Binds weakly mRNA.
What are the official names of this protein?
Eukaryotic translation initiation factor 4H, eIF-4H, Williams-Beuren syndrome chromosomal region 1 protein.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region.
Protein: NUOI_BRASO
Sequence: MNISATARSLLLQEFVSAFFLAMRYFFKPKPTLNYPFEKGPISPRFRGEHALRRYPNGEERCIACKLCEAVCPAQAITIEAGPRRNDGTRRTVRYDIDMVKCIYCGLCQEACPVDAIVEGPNFEFATETREELYYDKAKLLANGDRWEREISKAIALDAPYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MRAY_SHEHH
Sequence: MLVYLAEYLTQFYSGFNVFSYVTFRAILGLMTALMFSLWWGPKMIARLQLMQIGQVVRNDGPESHFSKRGTPTMGGLLILAGVFISVLLWGDLDSRYVWVVLFVLGSFGLIGFIDDYRKVVRKDTKGLIARWKYLLQSLAALLIAVYLYASAQSPGETQLVVPFFKDVMPQLGGFFIVLVYFTIVGSSNAVNLTDGLDGLAIMPTVMVAAAFALIAYLSGHVQFASYLHLPYLPGAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLSLGAALGTIAVLVRQEILLVIMGGVFVMETVSVILQVGSYKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLFLVLLGLATLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PLSX_SHIDS
Sequence: MTRLTLALDVMGGDFGPSVTVPAALQALNSNSQLTLLLVGNPDAITPLLAKADSEQRSRLQIIPAQSVIASDARPSQAIRASRGSSMRMALELVKEGRAQACVSAGNTGALMGLAKLLLKPLEGIERPALVTVLPHQQKGKTVVLDLGANVDCDSTMLVQFAIMGSVLAEEVVEIPNPRVALLNIGEEEVKGLDSIRDASAVLKTIPSINYIGYLEANELLTGKTDVLVCDGFTGNVTLKTMEGVVRMFLSLLKSQGEGKKRSWWLLLLKRWLQKSLTRRFSHLNPDQYNGACLLGLRGTVIKSHGAANQRAFAVAIEQAVQAVQRQVPQRIAARLESVYPAGFELLDGGKSGTLR
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: PYRH_STRT2
Sequence: MAEPKYKRVLIKLSGEALAGEKGVGIDLPTVQAIAKEIAEVADSGIQIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTTMNALVMADSLKQLGVDTRVQTAIDMKSVAEPYIRGRALRHFEKGRIVIFAAGIGSPYFSTDTTAALRAAEIESDAILMAKNGVDGVYNDDPRKNADAVKFDKLTHVEVIKRGLKIIDATASTLSMDNDIDLVVFNMNEPGNIKRVIFGEQIGTTVSNKAELRK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOY_LACDA
Sequence: MIYKVLYQKDKIVNPRRETTQTLYMEADNIVQARALVEQNTPYNIELIQELTGNSLKYEQEHADFKLTAFGQTNSED
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: ILVC_SALEP
Sequence: MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSDVVRSVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVAEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQFEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGSAIPEGAVDNAQLRDVNDAIRSHAIEQVGKKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: UVRC_SALHS
Sequence: MSEIFDAKAFLKTVTSQPGVYRMYDAGGAVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQHIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPVRQCENSVYRNRSRPCLQYQIGRCLGPCVAGLVGEEEYAQQVEYVRLFLSGKDDQVLTQLIARMEKASQDLAFEEAARIRDQIQAVRRVTEKQFVSNAGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELGEVVETFVGQFYLQGSQMRTLPGEILLDFNLSDKTLLADSLSELAGRRIHVQTKPRGDRARYLKLARTNAATALITKLSQQSTITQRLTALAAVLKLPAIKRMECFDISHTMGEQTVASCVVFDANGPLRAEYRRYNIAGITPGDDYAAMNQVLRRRYGKAIEESKIPDVILIDGGKGQLAQAKAVFAELDVPWDKHHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSTLETIEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_SALRD
Sequence: MQARAVRRHIRSSPLKMRRVINLVRDRSVPEAVAILDYMPQKVTGVVEKTIRSAVYNLMDQHDERFDEGALKLKEIRADEGPTFQRHQARARGRAAPIRKRTTHLKVVVAVEEEAPEEAAA
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: DTD_BURO1
Sequence: MIALIQRVTRADVRVGGRTTGEIGAGLLALVCAERGDTEAAADKLLAKLLGYRVFSDAAGKMNLPVSNIDGEGRAGGLLLVSQFTLAADTNSGLRPSFTPAAPPDEGARLFDYFVAAARARHPIVETGEFGADMQVSLVNDGPVTFWLQVRP
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
Protein: GCST_FRAAA
Sequence: MADLRRSPLYGRHVDLGAKMAGFGGWEMPIEYAGRGVLAEHQAVRGAVGIFDVSHLGKAEVTGAGAAEFVNACLSNDLGRIAPGQAQYTLCCNDEGGVVDDLIAYLFSGERVLLVPNAANNAEVVARLAAAAPAGVSVTDRHTGFGVLAVQGPAAPTLVAALGLPTDGAYMSFVEAAWKGRPVIVCRSGYTGERGYELLPRWDDTPALWDALFAAGEGLGASPVGLGARDTLRTEMGYPLHGQDLSPTITPVQARSGWAVGWGKERFWGREALLAERAAGPARLLWGLASTGRAIPRPHMPVTAADGAPVGEVTSGTFSPTLRQGIGLALLDRGVAEGDTVNVDVRGRPGPMTVVRPPFVPSTPR
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: PGK_LISMF
Sequence: MAKKVVTDLDLKDKKVLVRVDFNVPMKDGKITNDNRIVAALPTIEYILEQNGKAILFSHLGKVKTEEDKEGKSLRPVAARLSELLGKEVKFVPTTRGPELEKAIDELKDGEVLLFENTRFEDIDGKKESKNDPELGKYWASLGDVFVNDAFGTAHRAHASNVGIASNLESAAGFLMEKEIKFIGGVVDNPARPLVAILGGAKVSDKIGVIENLLTKADKVLVGGGMTFTFMAAQGQEIGKSLLEADKVELAKGLLEKAGNKLVLPVDAVVSKEFSNDAPFHTVSADSIPADEMGLDIGQATIDLFTKELQGAKTVVWNGPMGVFELSNFAKGTIGVCEAIANLTDATTIIGGGDSAAAAMDLGFADKFTHISTGGGASLEYLEGKELPGVASISDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_ARCFU
Sequence: MKLGFVGAGRVGSTSAFTCLLNLDVDEIALVDIAEDLAVGEAMDLAHAAAGIDKYPKIVGGADYSLLKGSEIIVVTAGLARKPGMTRLDLAHKNAGIIKDIAKKIVENAPESKILVVTNPMDVMTYIMWKESGKPRNEVFGMGNQLDSQRLKERLYNAGARNIRRAWIIGEHGDSMFVAKSLADFDGEVDWEAVENDVRFVAAEVIKRKGATIFGPAVAIYRMVKAVVEDTGEIIPTSMILQGEYGIENVAVGVPAKLGKNGAEVADIKLSDEEIEKLRNSAKILRERLEELGY
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.  Can also oxidize tartrate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K0825_MOUSE
Sequence: MDALQEYSHNSFDLQCLLNSFPGDLEFKQIFSDIGEQMEQNAASIEHCIEEIQSEVNKLCPDAQLQTTSDCFKWLTSYNYNLSKSPSISHGDLINFLKTMKDLLNNEDNHEEMILDLLWDLSCQSSISFLSSLGGTTFCHLSRTSIHSVEDFSSVDVKSVWDDVRLHLRRFLVNRLERYNEINNSQQKIELKSQCMKQFLLLYSESEVLVKYQSIQKRLLDTFLQDSFPSCNRESDLERIVCGYQSTMLMLYSMIKEDFNVLCEILAPSSLVQFFNETYLDTVTEEMTKILEYFCELQFKENAVPVVKTSKSCNKRRGAVHALVSPECSQKERRPSLSLEELRFLSQLTESFVKLENSIQELFAETLSLLQMPRSSPGILEKSKKEVMVEKLIANENNKPPEALLPVKEATLLEFGWRNAFKEVPLAIAHCISAAIEGFSTQVLQQEQTERTSSVSYTINLVNVPQLCPEGHIFPEEEQPKRVAKFCSDIIEKLDTMLLLALACRDDSPQEIKENLVEAYSKVATAVLERLQERGKEVPSRAPLKNLHSILSSATYVSQRFTHYDNLMKETTKKPIFLVPVQRYQEFINTVQFQVTDYCARVCAMSILQDAESHHWDDYKAFYEGERCSFAIQMWHYFSLALHHDLWTILPPKLAQEILAEMLEKSLGLLASRYARAHPSPKRTAQIRLDVMAILIFTENMLWSICSSGQEILNPHKFNNHKIFKIHTHCNNLFTTLAILTSPLTELYKTFQHGVDESPSNSLTPLFNQPLHWISCMSQFYPSLLRPPSVGGLTAQGQLKLLLSQPCCKWNLLLDTLLHSGGLIPRILLKSSKQAAGMESKQSAGGSLVGAIFEVLYHCHLSSQTFGNVFMSHMEEEQLWDFLFNIPVSSFTESQPEVIHCLRLALMDSVKDTVQQIISIMRCRRNSETNLNKPRVPDHLLQSIPQGWNYIPRDSRGKESNKGITELAAQAVSIVLSKLPTVIACLPPTIKYFFFLSERKMSKNLAELKKAGLLVWNLIIIICRIFEDGNTVERLTGSSLDRWSKEKLGLICLCLESILGKQSNPSQLTQKVILSIERQKPNWMEQQLLKARTLSIQCAFTRMEENSGSEGEAALELTEQKTNAMVLDLCHKPGGSKYLQQIYHIMQLNEEYLKEQLFAMNGSEEKPLLIRPLKVALRDEDQPPAFNPFHVHKVVSESMLDQVATVTWCCDWSNLLPNYLGLNKMTFGALFKNRWEMRKDETLEEKEKMMLEHLKQNCTIQDFSTSDSKTEQ
What are the official names of this protein?
Uncharacterized protein KIAA0825 homolog.
Protein: RIMM_CUPNH
Sequence: MTERKQGAARPLNRPLVQPQGEPQKACKLPAALLYADPLPEDLVEVGYIGAAYGIRGWIKVLPHADDASALLHARRWWLLAPPQAGLVAADASRAQPVCVKIAQSREHSGTVVAQASGVADRNLAEALKGRRVWIRRADFPAPEEDEFYWVDLIGCTVSNEQGELLGEVSGLIDNGAHQILQVACVLPDGKAGERLIPFVDAFLRSVDTAGKRIVVDWGLDY
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INS2_KATPE
Sequence: AAPPQHLCGSHLVDALYLVCGERGFFYNPKGIVEQCCHKPCNIFDLQNYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver (By similarity).
What are the official names of this protein?
Insulin-2.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FUCL3_ANGJA
Sequence: MEVKMIILLFQILAISTLKSDSADIPEGYIQENVALRGRATQSAQLKGEFAGFAHASNAIDGNRDSNYHHGSCSHTEGDNSWWRVDLKQVYTITSVTITNRGDCCGERISGARILIGKHLENNGINNPECSTINIMAAGETKTFHCPQPMIGRYVTVYLPKAESLQLCEVEVNVLFPAPC
What is the function of this protein?
Acts as a defensive agent.  Recognizes blood group fucosylated oligosaccharides including A, B, H and Lewis B-type antigens.  Does not recognize Lewis A antigen and has low affinity for monovalent haptens.
What are the official names of this protein?
Fucolectin-3.
What is the protein family that this protein belongs to?
Belongs to the fucolectin family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: NEK3_MOUSE
Sequence: MDNYTVLRVIGQGSFGRALLVLQESSNQTFAMKEIRLLKSDTQTSRKEAVLLAKMKHPNIVAFKESFEAEGYLYIVMEYCDGGDLMQRIKQQKGKLFPEDTILNWFIQICLGVNHIHKRRVLHRDIKSKNVFLTHNGKVKLGDFGSARLLSSPMAFACTYVGTPYYVPPEIWENLPYNNKSDIWSLGCILYELCALKHPFQANSWKNLILKICQGPIHPLPALYSCKLQGLVKQMLKRNPSHRPSATTLLCRGSLAPLVPKCLPPQIIREYGEQILDEIKISTPKNMKKQDSNRVRRALGEANSASMQEEERGRKCSHTELESTGTTPAGNALERAARGNPESGNPQEHGRHTSPASPHRPWWERHGPSSNVEALEKASILTSSFTAEDDRGGSVIKYEENARRQWVREPPEALLSMLKDADLSQAFQTYTIYRPGAEGFLKGPLSEDTASDSVDGDLDSVMLDPERFEPRLDEEDTDFEEDNENPDWVSELKKHVGYGDGPGGQLLGERA
What is the function of this protein?
Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules.  Regulates microtubule acetylation in neurons.  Contributes to prolactin-mediated phosphorylation of PXN and VAV2.
What are the official names of this protein?
Serine/threonine-protein kinase Nek3, Never in mitosis A-related kinase 3, NimA-related protein kinase 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, axon.
Protein: RUVA_GEOSM
Sequence: MIALLTGKLAYKSPEFIILDVNGVGYQVHIPFSTYYTLPAEGGALSLQIHTSVKEDAINLYGFRTQQEKELFQLLIGVSGVGPKLATGILSNSEPSELADSLVNGNLARLSAIPGIGKKTAERLVLELKEKMKKLGLAQPQAGGATAPAKQEIRDDVLSALINLGYKEAVVQKALAELKVTEDATVELVLKQALKILMK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.