PharMolix/UniProtQA huggingface dataset:
Protein: PCRB_LISMC
Sequence: MKHLFKLDPAKNLPMNDLTKLVHSGTNGFIIGGTDNVQIEAVQKLYELLGETDLPIFLEISNESMILPEADHFLIPVVLNTENSKWTHGLHQELIKEMGAFIPWKRVTAEGYVILNKDAKVAHLTEAKTDLTDEDIVAYARLAENIFHLPIFYVEYSGMYGDPEVVRKASAALSNTKFWYGGGIRSKEQAAEMVKYADTIIVGNIIYEDLEKALETATIFRKKTV
What is the function of this protein?
Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP).  This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.
What are the official names of this protein?
Heptaprenylglyceryl phosphate synthase, HepGP synthase, Glycerol-1-phosphate heptaprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group I subfamily.
Protein: CUTC_SALTI
Sequence: MALLEICCYSMECALTAQRNGADRIELCAAPKEGGLTPSFGILRSVREHITIPVHPIIRPRGGDFYYTDGEFAAMLEDIRLVRELGFPGLVTGVLTVDGDVDMSRMEKIMAAAGPLAVTFHRAFDMCANPFNALKNLADAGVARVLTSGQKADAAQGLSIIMELIAQGDAPIIMAGAGVRANNLQNFLDAGVREVHSSAGVLLPSPMRYRNQGLSMSADIQADEYSRYRVEGAAVAENERNHCSPSGQMIFTVASCRPI
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_THEFY
Sequence: MTELLKLSAAELGAAIASGETSAVEATQAYLDRIAEVDGQIHAFLHVAADKALEQARAVDARRAAGEKLGPLAGVPVAHKDVFTTKDMPTTAASKILEGWQSPYDATVTERLRDAGLVILGKTNLDEFAMGSSTENSAYGPTRNPWDTDRVPGGSSGGSSAAVAAFEAPLATGTDTGGSIRQPAAVCGLVGAKPTYGTSSRYGLIAFASSLDTPGPIARNVLDAALLHEAFSGHDPRDSTSVNEPVPPVVEAARRADVSGMRIGVVKELSGEGYQPGVMQRFTEAVELFESLGAKIVEVSCPSFTAALAAYYLIAPSECSSNLARFDAMRYGLRVGDDGTRSADEVMALTRAQGFGPEVKRRIILGTYALSSGYYDAYYGSAQKVRTLIKRDFEAAFQQADVLVSPTTPTTAFRLGERIDDPMAMYLADLCTIPTNLAGNAALSVPCGLAPEDNMPVGLHIMAPTLADDRAYQAGAAVEAALRDKWGGDLLSQCAYAV
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: NU192_CHATD
Sequence: MTDLRKLEALQALHAELVAVRQHRFEGLQVLETLLEEQTDAFKALIAKPARDTKDREALGKEPKKLKIGEEEYSLNEDFVNDCLKLADELDLNEKESARILIDCDAEGDVETQSRPLWECGVIRFHQERKYLLDCMRLILEIAADEDIDAGLQESFGVAAEDKIFGIPPPWERNKENQPTQVKKFIPRCMEAMKGVRSMLQCMADKANARNMLQQASLVRPLDNQETLDFSRLSLVEQHECLASILHAAVQRHHATIADFQDFIKILRKWDKYDHFLIHLIPVLAAYITEFGSPEGMGDLQQARRLNDFICKGGDEDSWALPVLGAAVRAWWIAEHNGFYLDDTVQDLRGINLDEEDEQRTKQFLDALKEGAFDFILSVAADCKAQEWQDPSQLGARQWLQRKIPSLPSEPFPFSHFLQHSLMVHLEGFVDATISNLPDVLRKLRTEEDEQRQLRPNHEQDMDLERFLIIISYAYEGRPDAAMSFWEDPDSNLAGFLQWASRRASTPLVSAFCEMLRCLADNEECATAAHNFLLDEGHQASGKMKRSQSLTWSQIFKELEYFTTKVCSERPNPPQASMHRPGRPGADPAEIEPESALMLECYLRLIAKLATESEIARKRLIMDEDFNLVDTILKLSVGVIPHRLRACIFYVLKALMIRKTHEELDAMWRWVEAWMTNPFSSLPGSQGAPQRISFLGQTPGPQECMEMMFREFGTGFEQSNAFIQLLTTLLVPPEGLNSLNDSVPFPEWLGSSIRTLGIEPYVDFVFDVFANRTKDISDPSQLRILRLSCLDFVMVCLVTFNEDLIVLGHESNISIDDAMAATNLATYVRLHPFSRVMEWLFNEKVITSLINTIHQDPISLGSASPDSPLVVSILRAIQVMIKALELQETYLHLVRPEVLRYQGEAGVRRKPVANAAYSAFEDGILSHLSLVVDLGKYCNLGHAELTLACLKLLEKISTSSRILSAWSPDSGRLGHRNKAIVQLERNGEGETISASLSASIMATLDPALAASGENYRVKLAILDFLYACLRATPDQPTIAHQLLGFHCELSKLGIEPKGPFDMQKSLFHSLLNVLITLTVSEEEQGMRGYLVTLKYRVLRILQLLWKSPLSASLVMDELRATNFLFHMLLREVQIQPQLPWDGQLVTGCEFLLSDASLAYIDYLASRAAIFEYIGKELCSVSQNRIPSIKRQIFDALNGQIFVDEEAPLTIPSIFDFFDFINTDYKWEEIPSPHFTYLKDLDLGPCILEHKYAGVHYDIRKAQEILALKRKEYEHSQLATPEFLETVELEEKVLIEWLTVRNRANLLLTARLNLLQAWANLLLVMIESNDFKSTPKMAFLLQALQAILPTLEAFSSLKSDEAFELARVAKVLLWKLDFSQDSDAGLDREQFTVGNLIGDKLFQLFQLCLSAISQCSGTPELRSLYYSICYRYLTAVVDNDATVAATPASSTIGPTRSVTNARARTLKAITLYGDRLLNVICDDAYGSDTTCQTAAMILLNALVHTSRASSAAGVSPADVDCPIIDALNRLNFIGVLVDSLKEILNEWLAPSSTFDPSLSTNASPSLPIPASPSQQYTSAKLALLLQLCQTRQGAKYVLQANLFRALEQSGVFAADPELVEVDSESGVPRVVALERHYALLVALARVVGAAVTARGAHNIVQGRKFLTQHRGLVVHVLKKNAGIGGGVVGNSLASSINGGSTATMTRRDEILAQQALEERIEELAEAFMLLITATGFLEYESEQVPSEQPRAHTTFFH
What is the function of this protein?
Functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  NUP192 is located to the NPC core at the nuclear membrane and is essential for de novo assembly of NPCs.
What are the official names of this protein?
Nucleoporin NUP192, Nuclear pore protein NUP192.
What is the protein family that this protein belongs to?
Belongs to the NUP186/NUP192/NUP205 family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Note=Cytoplasmic and nucleoplasmic side of the nuclear pore complex in the nuclear envelope (symmetric distribution).
Protein: ABDH_ECO24
Sequence: MQHKLLINGELVSGEGEKQPVYNPATGDVLLEIAEASAEQVDAAVRAADAAFAEWGQTTPKVRAECLLKLADVIEENGQVFAELESRNCGKPLHSAFNDEIPAIVDVFRFFAGAARCLNGLAAGEYLEGHTSMIRRDPLGVVASIAPWNYPLMMAAWKLAPALAAGNCVVLKPSEITPLTALKLAELAKDIFPAGVINVLFGRGKTVGDPLTGHPKVRMVSLTGSIATGEHIISHTASSIKRTHMELGGKAPVIVFDDADIEAVVEGVRTFGYYNAGQDCTAACRIYAQKGIYDTLVEKLGAAVATLKSGAPDDESTELGPLSSLAHLERVSKAVEEAKATGHIKVITGGEKRKGNGYYYAPTLLAGALQDDAIVQKEVFGPVVSVTPFDNEEQVVNWANDSQYGLASSVWTKDVGRAHRVSARLQYGCTWVNTHFMLVSEMPHGGQKLSGYGKDMSLYGLEDYTVVRHVMVKH
What is the function of this protein?
Catalyzes the oxidation 4-aminobutanal (gamma-aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA).  This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4-aminobutanal.  Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Gamma-aminobutyraldehyde dehydrogenase, ABALDH, 1-pyrroline dehydrogenase, 4-aminobutanal dehydrogenase, 5-aminopentanal dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. Gamma-aminobutyraldehyde dehydrogenase subfamily.
Protein: IF1_PSEA7
Sequence: MSKEDSFEMEGTVVDTLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVRVELTPYDLSKGRITYRAR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5138_CUPPJ
Sequence: MQVLVDADACPVVVKEMLYRAAQRLEVCVTLVANKFLRTPPSRFIRALQVPAGFDAADDRIVELVIHGDLVITADIPLAAAALEKGAYVLDPRGSWFSRENIQERLTMRDVMEQLRSSGIDTGGPAPYAAQDGKAFAGQLDRFLARHVSP
What are the official names of this protein?
UPF0178 protein Reut_B5138.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: RIMM_FINM2
Sequence: MEYIAVAEVLNTHGIKGCLKMRPLTDNIERFDEDICYYLGDKKVKVTIQNYRMYKGFLYIDFEEFNDINEVLGFKKQYLYIDEKDRYELKDGSFYIDDLIGLKAYFNGEYIGDLVDVISIYSNDVYVIKNDEKEFMIPAVKEFIKKIDLENGLIDVVIIEGM
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_HYDS0
Sequence: MFKDFNFSIYLVTDDAFFVDRDVVRTIEQAIEGGITAVQYRFKNKPSRKMYEELLVLRDITKQNKVALIVNDRVDLAIAVKADGVHVGQEDLPPDVCKKIIPEDMIVGYSVNNLEQLKDAMTMPIDYIGFGSVFHTKTKKDYKYVGLEALCKATNITSIPIIAIGGITHYNLKDVLKCKVKGVAVVSAILGFEDVKRAASDFKQMYKESLSMQI
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: MNMA_POLNA
Sequence: MDKQHSKQRIVVGLSGGVDSAVTAYLLKQQGHEVIGIFMKNWEDDDDSEFCSSNIDFVDAAAVADVIGIEIEHVNFAANYKDRVFAEFLREYQAGRTPNPDILCNAEIKFKAFLDHAMRLGAEKIATGHYARVRQNEATGLHELLKGLDPSKDQSYFLHRLNQAQLSKTLFPVGELHKTEVRRIADEIGLPNARKKDSTGICFIGERPFRDFLNRYIAKAPGPVKNDQGRILGEHVGLSFYTLGQRQGLGIGGVKARGADLKAAQARGQRGVGEHEPWFVARKDMDSNTLWVVQGHDHPWLQSTLLNAQDCSWVAGSAPALGAMAAKTRYRQADAACELVSATAGGCELAFLDAQWAVTPGQSAVLYQGEVCLGGGVIASSNVQNLPGGKPAVA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEND_AERHH
Sequence: MSARQEFASHHATFNHVWSSLLLEELFRLGVRDIALASGSRSAPLTMAAAAHPGFRRHLHFDERGLGFMALGLAKGSGRPVAVIMTSGTAVANLWPAVAEAQLTGVPLIILSADRPPELIDNGANQAIDQQGIFGRYPVYQQNLPSPTATIPAAFVLSSVDQALAQQARTPGPVHFNCMYPEPLYPGDAYLDFSAYLAPLGDWLRSSEPWSPWQLTQAPCPCQPDWDELQGKRGLIVAGRIQDPVQAKAVAALAERLGWPLLADLQSQLRFDGRNLVHADLALQHSGFVAELARAEVLLQFGARLISKRLGQFIKQQPWQAYWLIDPQPARLDPDYRLRRRLLCDPAAFAAAHPVAHPHLPWHRLAERQQAVSQQVRSACERFSELGVCHRLNQLIRGQLFVGNSMPARLMDMLGEAGKGPSRVMTNRGASGIDGLIATAYGFAQSVQPGSNEPTTLLLGDLSALHDLNSLALLGKSSRPLVVILLNNDGGSIFRMLPVPTQDALLETYYCLPHGLHFEHAAAMFGLHYRTPASLADFERDYTTALEKGVTLIEIKVPSSEVAEDLKALGSAIRGS
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: MRAY_GLAP5
Sequence: MLVWLAEYLVQYNTAFNVVSYITFRSIMALLTALIIGLWIGSTVIRRLQILKFGQEVRHDGPESHYKKRGTPTMGGIMILFAIGVSTLLWADLRNPYVWFVLFILFGYGVVGFVDDYWKIARKNTDGLIARWKYFWLSVIALVSAFGMYAIGKDTAATQLVVPFFKDVMPQLGLFYIVLTYFVIVGTSNAVNLTDGLDGLAIVPLIMVAGAFALIAWATGNYNFAQYLHIPYIKYSGELVILCTAIVGAGLGFLWFNTYPAQVFMGDVGSLSLGGALGVIAVLVRQELLLVVMGGVFVVEALSVILQVGSYKLRQKRIFRMAPIHHHFELKGWPEPRVIVRFWIITLMLVLIGLVTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TPIS_BRASO
Sequence: MTDRIRPLIAGNWKMNGLKASAAEFEAMLAGAAEVTGKADLLVCPPATLLAAFAEKTRGGKAVAVGAQDCHAKASGAHTGDISAEMLADAGASAVIVGHSERRADHGESDVVVHQKAEAAWRAGLVAIVCVGETQQQRDAGLTLEILRGQLTLSLPEGSRADNLIVAYEPVWAIGTGLTPTAGDVEQIHSFIRQLLIVRFKEQGARMRILYGGSVKPSNAAELMAVANVNGALVGGASLKAADFLAIAKGC
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M6A_STRP6
Sequence: MAKNNTNRHYSLRKLKKGTASVAVALSVIGAGLVVNTNEVSARVFPRGTVENPDKARELLNKYDVENSMLQANNDKLTTENKNLTDQNKELKAEENRLTTENKGLTKKLSEAEEEAANKEQESKETIGTLKKILDETVKDKIAREQKSKQDIGALKQELAKKDEGNKVSEASRKGLRRDLDASREAKKQVEKDLANLTAELDKVKEEKQISDASRKGLRRDLDASREAKKQVEKDLANLTAELDKVKEEKQISDASRQGLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEQLAKQAEELAKLRAGKASDSQTPDAKPGNKVVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETANPFFTAAALTVMATAGVAAVVKRKEEN
What is the function of this protein?
Mediates the attachment of S. pyogenes to skin epithelial cells through the binding of the human membrane cofactor protein CD46.  Also binds to the factor H and factor H-like protein 1.  These interactions could contribute to the fact that the M6 protein protects the bacterium from the phagocytosis by regulating the complement activation on the bacterial surface (By similarity).
What are the official names of this protein?
M protein, serotype 6.
What is the protein family that this protein belongs to?
Belongs to the M protein family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: YOME_BACSU
Sequence: MAGFYRYDQNLDKYVPMPVELLASEGEEYTAPKITQKFNEVETKTTEILNKVLTDDRYFTVTSSFKQDATLGIEYYVTKVTPKTTEAKKSMVQKTFAYDFEKSIDPTSSYFGTTNRETVLSMAKRKRSVVAINASGWRSNGEVMGLQIKDGVLYKDYDAAGYTGAEACVFFDDGTMKVYGNREVDADILISKGARNSFAFGIWLVKDSKPRTAQMTTWADLNVKHPRQAIGQRSDGTLVIITVDGRSLRSSGITAYDMPSLFLSEGCINAFLLDGGGSSQTAVEGKYINNISDGIERAVVDTLTISYPDDDTDSRFFEVQEGRGLATSLNRRVEFIESKPTWNVLDLGFSPDGLIDNTAKFKKALSDLSEKGGGKLHFPKGTYLIGKQNTTSASEKIELPSNVSIVGERRSYTKLLRNPNHSLDELLRITDHNYIEGIEIDGNSSVNKSSCRLIAGGNIKSFKMKDCSLVNATDRGVSIHGIGKSITIEGMYISNIANECINVAEGEIIKLIDSEITFSGTALWVGNAANIFTKNNLAKSLKTFVRYKNSQNAICSGNIITNNIDRAIWGSVREAVFSDNVFKQCHSDYHLYFIQEDTGTNDLIVTGNSVYSDVEGTAFIRTPSDIDRRRVSGNVGNIPSLNLD
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YomE.
Protein: FUR4_YEAST
Sequence: MPDNLSLHLSGSSKRLNSRQLMESSNETFAPNNVDLEKEYKSSQSNITTEVYEASSFEEKVSSEKPQYSSFWKKIYYEYVVVDKSILGVSILDSFMYNQDLKPVEKERRVWSWYNYCYFWLAECFNINTWQIAATGLQLGLNWWQCWITIWIGYGFVGAFVVLASRVGSAYHLSFPISSRASFGIFFSLWPVINRVVMAIVWYSVQAYIAATPVSLMLKSIFGKDLQDKIPDHFGSPNATTYEFMCFFIFWAASLPFLLVPPHKIRHLFTVKAVLVPFASFGFLIWAIRRAHGRIALGSLTDVQPHGSAFSWAFLRSLMGCMANFSTMVINAPDFSRFSKNPNSALWSQLVCIPFLFSITCLIGILVTAAGYEIYGINYWSPLDVLEKFLQTTYNKGTRAGVFLISFVFAVAQLGTNISANSLSCGTDMSAIFPKFINIKRGSLFCAAMALCICPWNLMATSSKFTMALSAYAIFLSSIAGVVCSDYFVVRRGYIKLTHIYSHQKGSFYMYGNRFGINWRALAAYLCGVAPCLPGFIAEVGAPAIKVSDGAMKLYYLSYWVGYGLSFSSYTALCYFFPVPGCPVNNIIKDKGWFQRWANVDDFEEEWKDTIERDDLVDDNISVYEHEHEKTFI
What is the function of this protein?
Transport of uracil.
What are the official names of this protein?
Uracil permease.
What is the protein family that this protein belongs to?
Belongs to the purine-cytosine permease (2.A.39) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: COMFA_BACSU
Sequence: MNVPVEKNSSFSKELQQTLRSRHLLRTELSFSDEMIEWHIKNGYITAENSISINKRRYRCNRCGQTDQRYFSFYHSSGKNKLYCRSCVMMGRVSEEVPLYSWKEENESNWKSIKLTWDGKLSSGQQKAANVLIEAISKKEELLIWAVCGAGKTEMLFPGIESALNQGLRVCIATPRTDVVLELAPRLKAAFQGADISALYGGSDDKGRLSPLMISTTHQLLRYKDAIDVMIIDEVDAFPYSADQTLQFAVQKARKKNSTLVYLSATPPKELKRKALNGQLHSVRIPARHHRKPLPEPRFVWCGNWKKKLNRNKIPPAVKRWIEFHVKEGRPVFLFVPSVSILEKAAACFKGVHCRTASVHAEDKHRKEKVQQFRDGQLDLLITTTILERGVTVPKVQTGVLGAESSIFTESALVQIAGRTGRHKEYADGDVIYFHFGKTKSMLDARKHIKEMNELAAKVECTD
What is the function of this protein?
Involved in transformation (competence for DNA uptake).  Required for DNA uptake but not for binding.  May provide the driving force for transport of DNA through an aqueous channel.
What are the official names of this protein?
ComF operon protein 1, ATP-dependent helicase ComFA.
What is the protein family that this protein belongs to?
Belongs to the helicase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes mostly to the cell poles during the development of competence. Colocalizes with ComGA (PubMed:16009133). During competence a number of proteins (at least CoiA, ComFA, ComGA, DprA, RecA and SsbB) are thought to colocalize at the cell pole, in a disruption of comEC ComFA no longer accumulates (PubMed:17630974). During development of competence ComGA and presumably ComFA colocalize in discrete foci which accumulate at the cell poles and then delocalize without the overall levels of proteins decreasing, these processes are coincident with the timing of transformability and the site of DNA uptake (PubMed:16009133).
Protein: Y134_TREPA
Sequence: MCKPRVWRIAHTIVHVGALLLGTSQLTTCDFSGIFATIQQEVAIKSPSIPGAIYGLVKAGDKLYATNGRLWEKELNGIKWKPVPFLDGQDKRIDSLAASNTCVFACVSGDGVYKYTAGTTSSQKESNTDKAQAVVQMSDGKVVLQCALGDEKTTPSDADERLLGGGQGYLVTSKGFYTLPGSASCEVISETKDVTCKAEAPILASACDGSNTYILTKDKVYCRYTNGSGSTPTTWCDVEHKVSEPLALAVFKNKGETFLLVGGQQGYGEIKIATASGSSSSSSCVPLTAENVHATTGWGANCSTPEGSAEQYRSTIGRWAVSGIYVIKKDTSGGRKKRSTSTDCERPDLYVAVGDASDTYTGLWKFDTATNTWNRE
What are the official names of this protein?
Uncharacterized lipoprotein TP_0134.
What is the protein family that this protein belongs to?
Belongs to the TP013X lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: HIS2_NOVAD
Sequence: MEHGEILARLEATIAERRLGDPSASYVAKLNAKGLAKIAQKVGEEGTETVIAALAGDRKELVGEAADLIFHLMVLLSAKDVPFAEVLAELARREGTSGIAEKASRSN
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BZR1_ARATH
Sequence: MTSDGATSTSAAAAAAAAAAARRKPSWRERENNRRRERRRRAVAAKIYTGLRAQGDYNLPKHCDNNEVLKALCVEAGWVVEEDGTTYRKGCKPLPGEIAGTSSRVTPYSSQNQSPLSSAFQSPIPSYQVSPSSSSFPSPSRGEPNNNMSSTFFPFLRNGGIPSSLPSLRISNSCPVTPPVSSPTSKNPKPLPNWESIAKQSMAIAKQSMASFNYPFYAVSAPASPTHRHQFHTPATIPECDESDSSTVDSGHWISFQKFAQQQPFSASMVPTSPTFNLVKPAPQQMSPNTAAFQEIGQSSEFKFENSQVKPWEGERIHDVGMEDLELTLGNGKARG
What is the function of this protein?
Transcriptional repressor that binds to the brassinosteroid (BR) response element (BRRE) 5'-CGTG(T/C)G-3' in gene promoter.  Regulates positively the brassinosteroid-signaling pathway (PubMed:33324437).  Mediates downstream growth responses and negative feedback regulation of brassinosteroid biosynthesis.  Promotes growth.  Modulates ovule initiation and development by monitoring the expression of genes related to ovule development (e. g.  HLL, ANT, and AP2).  Regulates negatively the abscisic acid (ABA) signaling pathway during the post-germination stage (PubMed:33324437).
What are the official names of this protein?
Protein BRASSINAZOLE-RESISTANT 1, Protein BIN2 SUBSTRATE 2.
What is the protein family that this protein belongs to?
Belongs to the BZR/LAT61 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: APOA1_NANGA
Sequence: MKAVVLAVAVLFLTGSQARHFWQQDEPQSPWDRVKDFATVYVDAVKDSGREYVSQFETSALGKQLNLNLLENWDTFGSTFGRLQEQLGPVTREFWDSLEKDTDWLRQEMNKDLEEVKQKVQPYLDEFQKKWEEEVERYRPKVEPLGAQLREGARQKLEELQKQLVPLGEDLRDRARLHVDALRTKLAPYSDQMRDRLAERLTALRDNPKLAEYHARATEHLKKLGEKTKPTLEDLRQGLMPWLESLKAKALSVLDEATQKLNTQ
What is the function of this protein?
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT).  As part of the SPAP complex, activates spermatozoa motility.
What are the official names of this protein?
Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL35_ALBFT
Sequence: MPKMKTKSAAKKRFRVRPGGTVKRGQAFKRHILTKKTTKNKRQLRGSTAVHETDMGRMSQMLPGRGI
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: Y294_RHOP2
Sequence: MTTPPERPETSVDRKLLEILVCPVTKGPLEFDAARQELISRGAKLAYPIRDGIPIMLPEEARKLG
What are the official names of this protein?
UPF0434 protein RPB_0294.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: NU5M_STRCA
Sequence: METTLLFNTSLLLTLMILLTPILLPLLSTKLQNTPLIITTTVKMAFFTSIIPTTIFIYSGTEAIISHWYWSFTPNLKIPLSFKMDQYSMLFLPVALFVTWSILQFAMWYMASEPHVTKFFIYLLMFLIAMLTLTIANNMFMLFIGWEGVGIMSFLLISWWHGRAEANTAALQAVIYNRIGDVGLILSMAWLASTLNTWEIQQISYESQTPILPLLGLILAATGKSAQFGLHPWLPAAMEGPTPVSALLHSSTMVVAGIFLLVRIHPLLANNQTALTTCLCLGALSTLFAATCALTQNDIKKIIAFSTSSQLGLMMVTIGLNLPQLAFLHISTHAFFKAMLFLCSGSIIHSLAGEQDIRKMGGLQKLLPTTTSCLTIGNLALMGTPFLAGFYSKDLIIESLNNSYLNAWALLLTLLATSFTATYSLRMTLMVQSGFSRIPPITPINENTPLVINPITRLALGSIMAGLLITSNILPTKTPPMTMPTIMKTAAIVVTILGILLALELSNMTHNLTAPKQNIYSNFSTTLGYFNPLAHRLSSMKLLNNGQKIASHLIDLSWYKKMGPEGLADLQLMAAKTSTPLHTGLIKTYLGTFALSILILLTLTH
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL34_STRZT
Sequence: MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: TRHO_STRPI
Sequence: MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADEGINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEENEQAFKKMFVRYKKEIVHLGLEDNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRNFRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKDPEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILTSEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: CLPR_SYNY3
Sequence: MEITAVQSSYYGDMAFKTPPPDLESLLLKERIVYLGMPLFSSDEVKQQVGIDVTQLIIAQLLYLQFDDPDKPIYFYINSTGTSWYTGDAVGFETEAFAICDTLNYIKPPVHTICIGQAMGTAAMILSSGTKGYRASLPHATIVLNQNRTGAQGQATDIQIRAKEVISNKQTMLEILSLNTGQTQEKLAKDMDRTFYLTPAQAKEYGLIDRVLESPAELPKPMAVI
What is the function of this protein?
Has lost the two conserved residues (Ser and His) proposed to be part of the active site.  Therefore it could be inactive.
What are the official names of this protein?
Putative ATP-dependent Clp protease proteolytic subunit-like, Endopeptidase Clp-like.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.