PharMolix/UniProtQA huggingface dataset:
Protein: CLPP_ILLOL
Sequence: MPIGVPKVPFRNPGEEGAVWVDVYNRLHRERLLFLGQGVDSEISNQLVGLMVYLSIEDDTRDLYLFINSPGGWVIPGIAIYDTMQFVPPDVHTICMGLAASMGSFLLAGGEITKRLAFPHARVMIHQPASSFYEAQTGEFILEAEELLKLRETITRVYAQRTGNPLWVVFEDMERDVFMSATEAQAHGIVDLVAVENTGDFA
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: RF3_DESAL
Sequence: MSKQQKKEVEQRRCFGIISHPDAGKTTLTEKFLLFGGAIQLAGAVKARKAARHATSDWMSIERDRGISVTTSVMTFSYRDFFINLLDTPGHQDFSEDTYRVLTAVDSALMVIDSAKGVEAQTEKLMEVCRMRNTPIITFINKMDRDGMAPLDLLSDIEEKLQIECAPLTWPIGAGKGFAGVYNLYKKELQLFTAGGKTRQKDGIVIQDLDDPKLAELIGESKAEELREDIELLEGAANPFEMEHYLSGSQTPVFFGSAINNFGITELLDALVEMAPAPGLRPAESRDVSPLEEDFSGFTFKIQANMDPAHRDRIAFVRICSGKFNRGMKVMHHRIGKEMIISNATMFMAQDRANVEEAWPGDIIGVHNHGTIKIGDTFTIKEPLKFTGIPNFAPEHFRRVMLKDPMKAKQLNKGLTQLAEEGAVQVFRPLTSADNILGAVGVLQFDVTMARLKAEYNVDCIYEAIDYNTARWVECPDNKMLDEFRKANQANLALDGEGQLAYLAPSQWRLGFVQENWPDVVFHKTREYN
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXC_ACIF2
Sequence: MIRQRTLKNMIWGTGIGLHSGKKVYIGLRPAPVNTGIVFHRSDIEGGAWIKADPLHVVDTRLSTNIGDGHIRVGTVEHLMSALAGLGIDNAYVDLDGPEVPIMDGSAAPFVFLIQCAGIEEQNAPKRFIRITKPLKAEDGDRWVQLEPFEGFKVSFAIDFDHPVMKNGGQEVTVDFARTSYLKEVARARTFGFMREVEALRRMGLALGGNLDNAIVVDDYRVLNEEGLRYTNEFVRHKVLDSIGDLYLLGHPLVGHFSGHKAGHALNNSLLRALLLRQDAWEFVDYAERRAPFSFADTLVTASA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: VIF_HV1MV
Sequence: MENRWQVLIVWQIDRQKVKAWNSLVKYHKYMSKKAANWRYRHHYESRNPKVSSAVYIPVAEADIVVTTYWGLMPGEREEHLGHGVSIEWQYKEYKTQIDPETADRMIHLHYFTCFTESAIRKAILGQRVLTKCEYLAGHSQVGTLQFLALKAVVKVKRNKPPLPSVQRLTEDRWNKPWKIRDQLGSHSMNGH
What is the function of this protein?
Counteracts the innate antiviral activity of host APOBEC3F and APOBEC3G.  Forms a complex with host APOBEC3F and APOBEC3G thus preventing the entry of these lethally hypermutating enzymes into progeny virions.  Recruits an active E3 ubiquitin ligase complex composed of elongin BC, CUL5, and RBX2 to induce polyubiquitination of APOBEC3G and APOBEC3F.  In turn, they are directed to the 26S proteasome for degradation.  Vif interaction with APOBEC3G also blocks its cytidine deaminase activity in a proteasome-independent manner, suggesting a dual inhibitory mechanism.  May interact directly with APOBEC3G mRNA in order to inhibit its translation.  Seems to play a role in viral morphology by affecting the stability of the viral nucleoprotein core.  Finally, Vif also contributes to the G2 cell cycle arrest observed in HIV infected cells.
What are the official names of this protein?
Virion infectivity factor, Vif, SOR protein.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group Vif protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Virion. Note=In the cytoplasm, seems to colocalize with intermediate filament vimentin. A fraction is associated with the cytoplasmic side of cellular membranes, presumably via the interaction with Pr55Gag precursor. Incorporated in virions at a ratio of approximately 7 to 20 molecules per virion.
Protein: MURC_BRUA4
Sequence: MKMPLNIGLVHFIGIGGIGMSGIAEVLHNLGYHVQGSDQSDSANVQRLREKGIEVFVGHKAENIGDAEVVVVSTAIKKNNPELVAAREKLLPIVRRAEMLAELMRFRHAVAIGGTHGKTTTTSMVAALLDAGHLDPTVINGGIINAYGTNARMGDGDWMVVEADESDGTFLKLPADIAVVTNIDPEHLDHYGNFENVRAAFAQFVENVPFYGFGVMCLDHPEVQALVSRIEDRRIVTYGQNPQADVRFVNHRMDGAASLFDVVIRSRKGEATEIKDLRLPMPGQHNVSNATAAIAVAHELGISADDIRRGLGSFGGVKRRFTHTGTWNGVEIFDDYGHHPVEIRAVLKAAREATKGRVVAIVQPHRYTRLASLFDEFAACFNDADTVIVTPVYTAGEDPIEGVNSEALVSRIKTAGHRDARYASGPEALAPLVASIAEPGDFVVCLGAGNITQWAYALPKELAEQGKK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSM3_PICST
Sequence: MPAPATTTSVDEQTLSVIDHLTKSYDNKSEIDSTLIDDYITVLGSIDLLGAIADFIPIINHILTDNLYHQIDPNRLLIELLQKIVSRLSFGQIVSVYSPEFIVSSLASSDNVPITKLCLSIIIQKLHEPETVSFIAENCISFILLKNYLSDAKLDLGIVNQIELYVNSLILNDVTNLLEEILTDTKFVILYNSIRNSENTILLARLLDFILILLTYKVDLPLDPRLYTFSNVEIVTFKDDPLFLILLVQFYVKLVQFSVLEEVSPVIGNFVNLYKDPTTDDFVKVEVIDILVKLSYATNSLLIEYGLELALNSELFKSHNLIKVYEYNEPDIKLLSNVNPDLIVHSSNVIYEDVLSNLSLLNNKQYFPILLNFIGSTDVFPRLEQDYFTTKLKHLPADKLYVILLEFSKFSHSRKFLLSNATLTNDYLLDNDNLTFVNNELWHTKLQVLENLVNATDSDSPELAHWKPYLQDSFNLMRHGKKIRDVVPQVSILDETL
What is the function of this protein?
Involved in DNA mismatch repair in slow-growing cells.  Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the 19S regulatory complex (RC) (By similarity).
What are the official names of this protein?
DNA mismatch repair protein HSM3.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S5B/HSM3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURA_SHESM
Sequence: MKPSKHLIFALFALAISQPTMAAPQPIDRVAVQINDGIVLESEITNMIDTVKANARAANQSLPSDSALRTQVIERLILTRLQLQMADRIGLHIGDLQLDQAIENIAREQKMTVAQMQQKIESEGLSFGQYREQLREEITLGEIQRIQVQRRIQVSPQEITGLVKLIQEQGMKDVEYQIGHILIDVPNNPNSEQLEASSKRANAVLERLKSGEDFRRTAIASSSGPKALEGGIWDYMNINEMPTLFAEVINGAKKGDIIGPIKSGAGFHIIKIMDARGLQTKEIEEVRARHILLKPSPILSEDRAKAMLEQFLKQIRSGEAKFEDLARQYSEDPGSAAKGGELGWAEPSIYVPEFAQTLNSLSQDQISEPFRTTHGWHITQLEERRKTDATDQFNTNRAHQLIFRRKFNEELQNWLDEMRADAYIEVFQPESNRG
What is the function of this protein?
Chaperone involved in the correct folding and assembly of outer membrane proteins.  Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins.  May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
What are the official names of this protein?
Chaperone SurA, Peptidyl-prolyl cis-trans isomerase SurA, PPIase SurA, Rotamase SurA.
What are the subcellular locations of this protein?
Periplasm. Note=Is capable of associating with the outer membrane.
Protein: KDPC_STAAS
Sequence: MNTIRNSICLTIITMVLCGFLFPLAITLIGQIFFYQQANGSLITYDNRIVGSKLIGQHWTETRYFHGRPSAVDYNMNPEKLYKNGVSSGGSNESNGNTELIARMKHHVKFGNSNVTIDAATSSGSGLDPHITVENALKQAPRIADARHISTSRVADLIQHRKQRGVLTNDYVNVLELNIALDKMKD
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: NSA2_AJECN
Sequence: MPQNEYIERWQKQYGERLDHEERTRKRIAREAHKQSHDAQSFRGLRAKLYQKKRHAEKIEMKKRIRAQEEKNVKSSAPNEPSSTPLPNYLLDRSQETNAKSLSSAIKNKRAEKAAQFSVPLPKVKGISEEEMFKVVKTGKKTAKKSWKRMITKPTFVGADFTRRPVKYERFIRPMGLRYKKANVTHPKLGVTVQLPIISVKKNPQSPMYTQLGVLTKGTIIEVNVSELGQVTASGKVLWGKFAQITNNCENDGCVNAVLLV
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.  May play a part in the quality control of pre-60S particles (By similarity).
What are the official names of this protein?
Ribosome biogenesis protein NSA2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MOBA_BACMK
Sequence: MSKCAGIVLAGGMSSRFGEPKALVGWKESTFIEHIVKVMESAVQEIVVISHTDIKERVEQLVQVPVIEDMSHYKGNGPLAGIVSGMEYIDSDWYIIMPCDAPNVSNEWITILLEQTSNEYDAVVPIINGRKQPLLAAYHNRVKEKIYALLQEEKRSMGQLLSQCNVKYIAGEDVQANVDWFINVNTKEEYVQAQKDLSNE
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRYPT_CRYDU
Sequence: GLLNGLALRLGKRALKKIIKRLCR
What is the function of this protein?
Antimicrobial peptide, active against the Gram-negative bacterium E. coli K12-594 (MIC=3. 12 ug/ml), the Gram-positive bacteria B. subtilis KCTC 3086 (MIC=3. 12 ug/ml), S. aureus KCTC 1928 (MIC=25 ug/ml) and M. luteus KCTC 3063 (MIC=1. 56 ug/ml), the antibiotic resistant bacteria methicillin-resistant S. aureus (MRSA) (MIC=25 ug/ml) and vancomycin-resistant Enterococci (VRE) (MIC=25 ug/ml), and the fungi C. albicans KCTC 7965 (MIC=50 ug/ml) and C. tropicalis KCTC 1925 (MIC=3. 12 ug/ml).  Has very low hemolytic activity on rat erythrocytes.
What are the official names of this protein?
Cryptonin.
Protein: QUEA_CERS5
Sequence: MKLSDFDFDLPERLIATRPARPRTAARLLLAEGDRIEDRHVRDLVGIFHPGDRLVLNNTRVIPARLVGTRTRGEACAKIEITLMEPAAAGGWRALAKPLRKLKEGETIRFSDALSAEVAEKGETDLRLVFDRAGEDFDAALAEAGAMPLPPYIAARRAPDAQDREDYQTVFARHAGAVAAPTASLHFDRPLLEALAANGVAFTEVTLHVGAGTFLPVKVEDVTTHRMHAEWGEVTEAAAAEIAATKAAGGRVIPVGTTALRLIESASAAGTIRPWRGETDIFIYPGYRFRVTDALMTNFHLPKSTLLMLVSALMGEARIRAIYDHAVRHDYRFFSYGDASLLIPGG
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSH_PHOPR
Sequence: MWLQVTNCSTLHSSLSYCGANTLSDMAKNLILWLVIAVVLMSVFQSFGPSDSAGRQVDYTTFVREIGQDQIREARFNEREITVFKRDNTRYVTYLPVFNDQKLLDDLINANVKVLGTPPEEPSLLASIFISWFPMLLLIGVWVFFMRQMQGGGGGKGAMSFGKSKARMMSEDQIKTTFADVAGCDEAKEDVKELVDYLRDPSRFQKLGGKIPTGILLVGPPGTGKTLLAKAIAGEAKVPFFTISGSDFVEMFVGVGASRVRDMFEQAKKAAPCIIFIDEIDAVGRQRGAGVGGGHDEREQTLNQMLVEMDGFEGNEGVIVIAATNRPDVLDPALLRPGRFDRQVVVGLPDVRGREQILKVHMRKVPLEGDVEPSLIARGTPGFSGADLANLVNEAALFAARGNKRVVSMQEFELAKDKIMMGAERKSMVMSEDQKESTAYHEAGHAIIGRLVPDHDPVYKVSIIPRGRALGVTMYLPEKDRISHSREFLESMLSSLYGGRLAEELIYGVDKVSTGASNDIERATDIARKMVTQWGFSEKMGPVLYADDEGEVFLGRSVTQTKHMSDDTARAIDMEIRALIDRNYERAREILAQNMDIMHAMKDALMKYETIDAAQIDDLMARKSEIRAPKGWGDTDDVMKSSPTTSESAPEAKTESAPEAKAEANVETEEKPVAADSEELKPKAEQAPKEDDKPQA
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: SYP_PARL1
Sequence: MRLSRYFLPTLKENPAEAQIASHRLMLRAGMVRQTAAGIYAWLPLGLAVLRKIEGIVRDEQKRAGAIELLMPTLQSADLWRQSGRYDAYGPEMLRIVDRHERDMLYGPTNEEMITDIFRGAVRSYRDLPRNLFHIQWKFRDEIRPRFGVMRGREFLMKDGYSFDLDVEGARRAYRKMFVSYLRSFARMGLKAIPMAADTGPIGGDMSHEFIILAETGESAVFCHRDLVDMAVPGDDIDYETDLNPVIAARTDLYAATDEKHDAAKFDAEVPKDKQLSARGIEVGHIFFFGTKYSQSMGALVTGPDGKEVPVQMGSYGIGVSRLVGAIIEASHDDAGIVWPDAVAPFTVGLINLKSGDAETDAACESIYEKLTAQGIDVLYDDTDERAGAKFSNMDLIGLPWQLVIGPRGLKSGTVELKRRATGEKEELSPEAALAKIAG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MECA_STRP4
Sequence: MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMSPDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFAKLADLVVFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDSDISRSVLQEYGQVLMSHDAVLNLQKIG
What is the function of this protein?
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
What are the official names of this protein?
Adapter protein MecA.
What is the protein family that this protein belongs to?
Belongs to the MecA family.
Protein: IAA13_ORYSI
Sequence: MAGADVDVGTELRLGLPGGGGGAAEAAAKAAKRGFEETIDLKLKLPTAGMEEAAAGKAEAPAAEKAKRPAEAAAADAEKPPAPKAQAVGWPPVRSFRRNIMTVQSVKSKKEEEADKQQQQPAANASGSNSSAFVKVSMDGAPYLRKVDLKMYNSYKDLSLALQKMFGTFTATGNNMNEVNGSDAVTTYEDKDGDWMLVGDVPWQMFVESCKRLRIMKGSEAIGLAPRAKDKYKNKS
What is the function of this protein?
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.
What are the official names of this protein?
Auxin-responsive protein IAA13, Indoleacetic acid-induced protein 13.
What is the protein family that this protein belongs to?
Belongs to the Aux/IAA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DUSP4_DICDI
Sequence: MNDVSRIFPGFYIGSLPAVNRNTLDKYQITHVCSVLNEFQPKWTKIYKYLHIDIYDSPSVDIMKYFDKTFQFIEEGRKDGGVLVHCFAGISRSATICIAYIMRKLNISFEDAHGLVSDARPIIYPNESFIKQLKKYELILKKNRENPQIVEKESEEEDDDEDDDDDDYDSDEDDDDDSEDDDFEEEFDNVVKKKNNNNKKVNVKNTTKVFSNISISSEQTTTSTTTVPTPTLNPETKIEETTTTTTATATATLVEEVVESTSPKATLGEHRYSCRKCSKDLFLDFDILDHEQGQGQTSFKWNKRDNTTCNKSVGANGEQIEDQNKVICTSYFISEIEFSLSQTYSGMEGKLFCPSCNEKLGSWSWSGEQCSCGAWIAPSFQIPKTRVDEKKVLK
What is the function of this protein?
Has a dual specificity toward Ser/Thr and Tyr-containing proteins.
What are the official names of this protein?
Probable dual specificity protein phosphatase DDB_G0281963.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Protein: YEJL_SHIB3
Sequence: MPQISRYSDEQVEQLLAELLNVLEKHKAPTDLSLMVLGNMVTNLINTSIAPAQRQAIANSFARALQSSINEDKAH
What are the official names of this protein?
UPF0352 protein YejL.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: CIDEC_HUMAN
Sequence: MEYAMKSLSLLYPKSLSRHVSVRTSVVTQQLLSEPSPKAPRARPCRVSTADRSVRKGIMAYSLEDLLLKVRDTLMLADKPFFLVLEEDGTTVETEEYFQALAGDTVFMVLQKGQKWQPPSEQGTRHPLSLSHKPAKKIDVARVTFDLYKLNPQDFIGCLNVKATFYDTYSLSYDLHCCGAKRIMKEAFRWALFSMQATGHVLLGTSCYLQQLLDATEEGQPPKGKASSLIPTCLKILQ
What is the function of this protein?
Lipid transferase specifically expressed in white adipose tissue, which promotes unilocular lipid droplet formation by mediating lipid droplet fusion (PubMed:18334488, PubMed:19843876, PubMed:20049731, PubMed:23399566, PubMed:30361435).  Lipid droplet fusion promotes their enlargement, restricting lipolysis and favoring lipid storage (PubMed:18334488, PubMed:19843876, PubMed:20049731, PubMed:23399566).  Localizes on the lipid droplet surface, at focal contact sites between lipid droplets, and mediates atypical lipid droplet fusion by undergoing liquid-liquid phase separation (LLPS) and promoting directional net neutral lipid transfer from the smaller to larger lipid droplets (PubMed:18334488, PubMed:19843876, PubMed:20049731, PubMed:23399566).  The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair (PubMed:18334488, PubMed:19843876, PubMed:20049731, PubMed:23399566).  Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1 (PubMed:23399566).  May also act as a CEBPB coactivator in the white adipose tissue to control the expression of a subset of CEBPB downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH (By similarity).  When overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to apoptosis induced by serum deprivation or TGFB treatment (PubMed:12429024).
What are the official names of this protein?
Lipid transferase CIDEC, Cell death activator CIDE-3, Cell death-inducing DFFA-like effector protein C, Fat-specific protein FSP27 homolog.
What is the protein family that this protein belongs to?
Belongs to the CIDE family.
What are the subcellular locations of this protein?
Nucleus. Endoplasmic reticulum. Lipid droplet. Note=Diffuses quickly on lipid droplet surface, but becomes trapped and clustered at lipid droplet contact sites, thereby enabling its rapid enrichment at lipid droplet contact sites.
Protein: ADDB_LACPL
Sequence: MSLQFVLGPAKMDHRRTMVAQLVATLMAKPQDQFFYLVPNHIKFDTEVDVLNRLAQAFGQPDLYAQTQVQVFSFTRLAWYLMKNEAAYQVPRLSAAGIDMLLYRILQRHADELRLFGGEISQTGFVTQLAREINELQTANLQPEDVVQLAANAQAGDLQAKLHDLAIVYKDFVAATADKYLKPADILVQLNAYLRRQDLHGTHVYVELAGFAQLPAQEQGIVTTMLEQGADVTISLMLDHKVVDRAPENGTLFYQSGRLYYRLYQYARIRQIPVSQDIYAETPRVAPGLVALDDFWRGQPQAATGYEEPNTNVHLFRTDSRQTELAQVGRMIRAMVAKKHADPADDYHYRDFLIMTRHLDAYQTMLAPTFHELEIPYFVDLQRSMADHPLVELINALFDIDAQQYQYRDVMRVLKTELLMPNINGQPMDRQAYRQAVDLTENFILKSGYHGQRWVQREDWQYFQLTEGDAGVETDQNAEISRQINLIHHFVAETLPPFFKKMRQAPDGKAAVTLLVNFLTSQGVTDQLLAWRDQALDRQDVRAAAEPEQTWQTFCGMLDEYVTILGAEPFEITDFLALLQAGFEGASYSQIPSTLDQVLISESGMVQSQDHKVVFMVGATDLVMPDRIMTNNLLSDVDKENLQLTLSSLDGDHYLNDSAVVQLGDESCLNYLAFLSARRHLFFSAPLKDDQETDLNWSNYVRRIQRQFNLREHTYLGTPDPTNADARPFVGTKRRTISHVIQVYRDVLTTNTDRNRVGAPLQPAPVWVWLRQQLTRDPQFGELARQLMAGLSYRNQPVKLTPASVEALYGHQIYTSISKLEEFYRNQYAYFLKYGLKLRERDVFELSAASTGEFFHAVLDGLIKALRSDQIPLAQASDQQLGQYLETVTRQILDQPQFTILTSSNRMAYLQRQLINTVRQIAFAIRNQSKLSAAEPKQTEILFGNVGKEHGLKALDFQIDATHSVHVRGKIDRLDQIQVADQSYLGIVDYKSSQHKFDFQEAYYGLAMQMLTYLDAVLHNEQALVGSDQAAVKLAGALYMHIQNPTLKPKDIQGGFEAALLKKNKYKGILLDDPQLLEHLDSELQQGNGTSKVYPFARKKDGSYSGGRAASLVTNDQLERLLQHNSQLIIAAAEAIFAGEIQLNPIRLNDKTTALQYSPYLSIMQFDAMLAENAYRDLPPLSAKQVLDLLKTQKGGENHE
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  This subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease RexB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 2 subfamily.
Protein: NADA_THEMA
Sequence: MVDEILKLKKEKGYIILAHNYQIPELQDIADFVGDSLQLARKAMELSEKKILFLGVDFMAELVKILNPDKKVIVPDRSATCPMANRLTPEIIREYREKFPDAPVVLYVNSTSECKTLADVICTSANAVEVVKKLDSSVVIFGPDRNLGEYVAEKTGKKVITIPENGHCPVHQFNAESIDAVRKKYPDAKVIVHPECPKPVRDKADYVGSTGQMEKIPEKDPSRIFVIGTEIGMIHKLKKKFPDREFVPLEMAVCVNMKKNTLENTLHALQTESFEVILPKEVIEKAKKPILRMFELMG
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_BACC4
Sequence: MNIEQFQSMLEEKGITLSSRQLEQFKIYFETLVEWNEKMNLTAITEKEEVYLKHFFDSITAAFYYDFSKPFSICDVGAGAGFPSIPLKICFPHLKVTIVDSLQKRINFLNHLAQKLELSDVAFCHDRAETFGKKEGVRESYDIVMARAVARLSVLSELCLPLVKVGGTFIAMKGAAANEEIENGKYALEVLGGELKEMSTFQLPFEESERNILLIEKKRKTPKKYPRKPGTPNKLPIEK
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PK81C_PSEFD
Sequence: MKSDTQVRAPTPKVGKQATAVTLGAFLSGAMMSLSAVMIPVVLQTNDQADQLLKQWALLYHYGHIIMPSLAILTTSLYAYIAYSKRAVGHQDWSAYAKAGLTTIAIVPFTLTIMEPTNDTLHELSRSTGNSLDIVQGLIVKWVWMHTVRSVFPMFGSILGFRGVLKECGVYSK
What is the function of this protein?
Anthrone oxygenase; part of the gene cluster that mediates the biosynthesis of an emodin derivative that may be involved in black Sigatoka disease of banana (PubMed:27388157, PubMed:30735556).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase PKS8-1 (Probable).  The atrochrysone carboxyl ACP thioesterase MYCFIDRAFT_190111 then breaks the thioester bond and releases the atrochrysone carboxylic acid from PKS8-1 (Probable).  The decarboxylase MYCFIDRAFT_34057 then catalyzes the concerted decarboxylation-elimination required to convert atochrysone carboxylic acid into emodin anthrone, which is further oxidized to emodin by the anthrone oxygenase MYCFIDRAFT_34418 (Probable).  The functions of the other tailoring enzymes as well as the final product of the cluster have still to be identified (Probable).
What are the official names of this protein?
Anthrone oxygenase MYCFIDRAFT_34418, PKS8-1 gene cluster protein MYCFIDRAFT_34418.
What is the protein family that this protein belongs to?
Belongs to the anthrone oxygenase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.