PharMolix/UniProtQA huggingface dataset:
Protein: DNAJ_ORITI
Sequence: MSELDYYQVLGVSRTASQEEIKRAYRKLVLKYHPDHNPGDKNAEQKIKNINEAYDILKDEKKRSAYDQLGHQTFKNSGGGNYQQHHGFTGGIDPNDIFENIFGDFMGARRSSKTAFSKKAGANLKYDISLTLEEAFYGVTKIISFKTALTCEACTGKGSLDNNSTSSCPTCRGSGVTRSQQGFFFFENTCQTCRGAGHVIKNPCTKCYGEGRYINTRNLEVKIPAGVKEGSRIKLTGEGEAGSRGGKTGDLYVCITLIPHNTFSVDGNDLHCQLDINCTTAALGGEVEVTDITGSKLKLKIPAGTQNNHKLKLSGKGMQILHSDRCGNMIVHVNIKVPKSLTKSQRELMIKLDKELNEASEEGFLSKVRNFWTSGSE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_BIFAA
Sequence: MAGTNPRAARIAALIQRVIASSMEAQLHDKRLANVTITEVRVTNDLQIAKVYWTQLGHEGHEQGERRRAQQALNQAKGRLRSLVGTKAGLRLTPQLEFIFDEVPGEAHEIEDILALAHKRDEELAKSRANAQYAGDADPYKHDEPDDDDFDDDDDVEVEDWDDDDEA
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MBP_CAVPO
Sequence: ASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFGSDRAAPKRGSGKDSHHAARTTHYGSLPQKSQRSQDENPVVHFFKNIVTPRTPPPSQGKGRGLSLSRFSWGAEGQKPGFGYGGRADYKSKGFKGAHDAQGTLSKIFKLGGRDSRSGSPMARR
What is the function of this protein?
Is, with PLP, the most abundant protein component of the myelin membrane in the CNS.  Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers.  Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity).
What are the official names of this protein?
Myelin basic protein, MBP.
What is the protein family that this protein belongs to?
Belongs to the myelin basic protein family.
What are the subcellular locations of this protein?
Myelin membrane; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic side of myelin.
Protein: RL7_MARMM
Sequence: MADVAKLCDELLALTILEAKELNDLLEEKGIKAAAAVAVAGPAGGGDAPAAEEKDEFDVVLTGAGDKKINVIKEVRAITGLGLKEAKDLVEGAPKAVKEAASKTEAEEIKAKLEAAGASVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: CAH_ENTCL
Sequence: MQAQVFRVPMSNPADVSGVAKLIDEGVIRAEEVVCVLGKTEGNGCVNDFTRGYTTLAFKVYFSEKLGVSRQEVGERIAFIMSGGTEGVMAPHCTIFTVQKTDNKQKTAAEGKRLAVQQIFTREFLPEEIGRMPQVTETADAVRRAMREAGIADASDVHFVQVKCPLLTAGRMHDAVERGHTVATEDTYESMGYSRGASALGIALALGEVEKANLSDEVITADYSLYSSVASTSAGIELMNNEIIVMGNSRAWGGDLVIGHAEMKDAIDGAAVRQALRDVGCCENDLPTVDELGRVVNVFAKAEASPDGEVRNRRHTMLDDSDINSTRHARAVVNAVIASIVGDPMVYVSGGSEHQGPAGGGPVAVIARTA
What is the function of this protein?
Responsible for the hydrolysis of cyanuric acid, an intermediate formed during catabolism of s-triazine based compounds in herbicides such as atrazine and polymers such as melamine.  Catalyzes the hydrolytic opening of the s-triazine ring of cyanuric acid (2,4,6-trihydroxy-s-triazine) to yield carbon dioxide and carboxybiuret, which spontaneously decarboxylates to biuret.
What are the official names of this protein?
Cyanuric acid amidohydrolase, CAH.
What is the protein family that this protein belongs to?
Belongs to the cyclic amide hydrolase (CyAH) family.
Protein: HSP74_YEAST
Sequence: MSKAVGIDLGTTYSCVAHFANDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAMNPHNTVFDAKRLIGRKFDDPEVTNDAKHYPFKVIDKGGKPVVQVEYKGETKTFTPEEISSMILTKMKETAENFLGTEVKDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKSQKEHNVLIFDLGGGTFDVSLLSIDEGVFEVKATAGDTHLGGEDFDSRLVNFLAEEFKRKNKKDLTTNQRSLRRLRTAAERAKRTLSSSAQTSIEIDSLFEGIDFYTSITRARFEELCADLFRSTLEPVEKVLADSKLDKSQIDEIVLVGGSTRIPKVQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSSTTQDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSAVEKGTGKSNKITITNDKGRLSKEDIDKMVAEAEKFKAEDEQEAQRVQAKNQLESYAFTLKNSVSENNFKEKVGEEDARKLEAAAQDAINWLDASQAASTEEYKERQKELEGVANPIMSKFYGAAGGAPGAGPVPGAGAGPTGAPDNGPTVEEVD
What are the official names of this protein?
Heat shock protein SSA4.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYN_DESPS
Sequence: MRQRITELLVAKAEEQVVTVAGWIRTRRDTGDFSFLEVNDGSTLINMQVIADKSLGNYEEEVKKLSTGCSVMVEGVLKESPAKGQSVEVHASSVTVVGWADPETYPLQKKRHSLEFLREISHLRPRTNAISAVARVRSRLSYAVHNFFQEKGFTQVHTPIITTSDCEGAGEMFQVAATGKDGHFFGAPAGLTVSGQLQAEVYATALGDVYTFGPTFRAENSNTSRHLAEFWMIEPEMAFCDLQGDMEVAEEMLKYVLADVLEHCVTDMNLFDKFISKGIIERLQSVLAHDFARVTYTEAVDQLLASGQKFDFAVKWGIDLQSEHERYLTEQVYKRPLIVTDYPAAIKPFYMRMNEDGKTVAAMDILVPGIGELVGGSQREERYDLLAERMEAAGLDLEEYGWYLDLRKYGTVPHAGFGLGFERLVQFVTGMANIREVIPFPRTPGFAPC
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPSD_MYCBO
Sequence: MTSLAERAAQLSPNARAALARELVRAGTTFPTDICEPVAVVGIGCRFPGNVTGPESFWQLLADGVDTIEQVPPDRWDADAFYDPDPSASGRMTTKWGGFVSDVDAFDADFFGITPREAVAMDPQHRILLEVAWEALEHAGIPPDSLSGTRTGVMMGLSSWDYTIVNIERRADIDAYLSTGTPHCAAVGRIAYLLGLRGPAVAVDTACSSSLVAIHLACQSLRLRETDVALAGGVQLTLSPFTAIALSKWSALSPTGRCNSFDANADGFVRGEGCGVVVLKRLADAVRDQDRVLAVVRGSATNSDGRSNGMTAPNALAQRDVITSALKLADVTPDSVNYVETHGTGTVLGDPIEFESLAATYGLGKGQGESPCALGSVKTNIGHLEAAAGVAGFIKAVLAVQRGHIPRNLHFTRWNPAIDASATRLFVPTESAPWPAAAGPRRAAVSSFGLSGTNAHVVVEQAPDTAVAAAGGMPYVSALNVSGKTAARVASAAAVLADWMSGPGAAAPLADVAHTLNRHRARHAKFATVIARDRAEAIAGLRALAAGQPRVGVVDCDQHAGGPGRVFVYSGQGSQWASMGQQLLANEPAFAKAVAELDPIFVDQVGFSLQQTLIDGDEVVGIDRIQPVLVGMQLALTELWRSYGVIPDAVIGHSMGEVSAAVVAGALTPEQGLRVITTRSRLMARLSGQGAMALLELDADAAEALIAGYPQVTLAVHASPRQTVIAGPPEQVDTVIAAVATQNRLARRVEVDVASHHPIIDPILPELRSALADLTPQPPSIPIISTTYESAQPVADADYWSANLRNPVRFHQAVTAAGVDHNTFIEISPHPVLTHALTDTLDPDGSHTVMSTMNRELDQTLYFHAQLAAVGVAASEHTTGRLVDLPPTPWHHQRFWVTDRSAMSELAATHPLLGAHIEMPRNGDHVWQTDVGTEVCPWLADHKVFGQPIMPAAGFAEIALAAASEALGTAADAVAPNIVINQFEVEQMLPLDGHTPLTTQLIRGGDSQIRVEIYSRTRGGEFCRHATAKVEQSPRECAHAHPEAQGPATGTTVSPADFYALLRQTGQHHGPAFAALSRIVRLADGSAETEISIPDEAPRHPGYRLHPVVLDAALQSVGAAIPDGEIAGSAEASYLPVSFETIRVYRDIGRHVRCRAHLTNLDGGTGKMGRIVLINDAGHIAAEVDGIYLRRVERRAVPLPLEQKIFDAEWTESPIAAVPAPEPAAETTRGSWLVLADATVDAPGKAQAKSMADDFVQQWRSPMRRVHTADIHDESAVLAAFAETAGDPEHPPVGVVVFVGGASSRLDDELAAARDTVWSITTVVRAVVGTWHGRSPRLWLVTGGGLSVADDEPGTPAAASLKGLVRVLAFEHPDMRTTLVDLDITQDPLTALSAELRNAGSGSRHDDVIAWRGERRFVERLSRATIDVSKGHPVVRQGASYVVTGGLGGLGLVVARWLVDRGAGRVVLGGRSDPTDEQCNVLAELQTRAEIVVVRGDVASPGVAEKLIETARQSGGQLRGVVHAAAVIEDSLVFSMSRDNLERVWAPKATGALRMHEATADCELDWWLGFSSAASLLGSPGQAAYACASAWLDALVGWRRASGLPAAVINWGPWSEVGVAQALVGSVLDTISVAEGIEALDSLLAADRIRTGVARLRADRALVAFPEIRSISYFTQVVEELDSAGDLGDWGGPDALADLDPGEARRAVTERMCARIAAVMGYTDQSTVEPAVPLDKPLTELGLDSLMAVRIRNGARADFGVEPPVALILQGASLHDLTADLMRQLGLNDPDPALNNADTIRDRARQRAAARHGAAMRRRPKPAVQGG
What is the function of this protein?
Part of the PpsABCDE complex involved in the biosynthesis of the lipid core common to phthiocerols and phenolphthiocerols by successive additions of malonyl-CoA or methylmalonyl-CoA extender units (PubMed:9201977).  PpsA can accept as substrate the activated forms of either icosanoyl (C20), docosanoyl (C22) or lignoceroyl (C24) groups from FadD26, or a (4-hydroxyphenyl)-C17 or (4-hydroxyphenyl)-C19 fatty acyl from FadD29 (By similarity).  PpsA initiates the biosynthesis and extends its substrate using a malonyl-CoA extender unit.  The PpsB and PpsC proteins add the second and third malonyl-CoA extender units.  PpsD adds an (R)-methylmalonyl unit and PpsE adds a second (R)-methylmalonyl unit.  The incorporation of the methylmalonyl units results in formation of two branched methyl groups in the elongated product (By similarity).
What are the official names of this protein?
Phenolphthiocerol/phthiocerol polyketide synthase subunit C, (Phenol)carboxyphthiodiolenone synthase subunit D, Beta-ketoacyl-acyl-carrier-protein synthase I, Phthiocerol synthesis polyketide synthase type I PpsD.
Protein: MFNB_METS3
Sequence: MLLLISPINHEEALESIKGGADIVDVKNPKEGSLGANFPWVIRDIREITPEDKLVSATLGDVPYKPGTVSLAAMGAHVSGADYIKVGLYGTKDYDEAVEVMENVAKTIKDVDNDTIVVASGYADAHRVGAVDPMEIPKVAKDAGCDLAMLDTAVKDGHTLFDYLSIEDLEKFVNEAHSYGLKTALAGSVKKEQLKPLNDIGCDVVGIRGAACVGGDRNTGKIHHTAVAELKELCDSF
What is the function of this protein?
Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).
What are the official names of this protein?
(5-formylfuran-3-yl)methyl phosphate synthase, 4-(hydroxymethyl)-2-furancarboxaldehyde-phosphate synthase, 4-HFC-P synthase.
What is the protein family that this protein belongs to?
Belongs to the MfnB family.
Protein: IBPA_ECOL6
Sequence: MRNFDLSPLYRSAIGFDRLFNHLENNQSQSNGGYPPYNVELVDENHYRIAIAVAGFAESELEITAQDNLLVVKGAHADEQKERTYLYQGIAERNFERKFQLAENIHVRGANLVNGLLYIDLERVIPEAKKPRRIEIN
What is the function of this protein?
Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpA, 16 kDa heat shock protein A.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNN_SALPB
Sequence: MKIGIIGAMEEEVTLLRDKIDNRQTITLGGCEIYTGQLNGTEVALLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGLASTLKVGDIVVSDEARYHDADVTAFGYEYGQLPGCPAGFKADDKLIAAAESCIRELNLNAVRGLIVSGDAFINGSVGLAKIRHNFPDAVAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQSTLMVETLVQKLAHG
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.  Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: VATE2_HUMAN
Sequence: MALSDVDVKKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKKEKQIEQQKKILMSTMRNQARLKVLRARNDLISDLLSEAKLRLSRIVEDPEVYQGLLDKLVLQGLLRLLEPVMIVRCRPQDLLLVEAAVQKAIPEYMTISQKHVEVQIDKEAYLAVNAAGGVEVYSGNQRIKVSNTLESRLDLSAKQKMPEIRMALFGANTNRKFFI
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons.  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
What are the official names of this protein?
V-type proton ATPase subunit E 2, V-ATPase subunit E 2, Vacuolar proton pump subunit E 2.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: PANB_BACC3
Sequence: MKTKTDFLKMKEQGEPITMLTAYDYPSAKLAEEAEVDMILVGDSLGMVVLGYDSTVPVTVEDMIHHTKAVRRGAKETFIVTDMPFMSYHVSLQDTMVNARRIVQESGAHALKVEGAGEVISTIHYLTNAGIPVVAHLGLTPQSVGVLGGYKVQGKDAESAKKLIEDAKKCEEAGAIALVLECVPMQLAELISEQLTIPTIGIGAGQKVDGQVLVYHDLISYGVNRVPKFVKQYTSVQEEIVRGISQYVAEVKTRQFPEEKHSFTMKEEECLALYGGKQS
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNTB_PECCP
Sequence: MESFAGKELQHSGAVHAYQLDGKGGITPIGEQDVVNSEKPCWLHLDSTLPASARWLNKTTLVPDSVRNALAGESIRPRVTRLGDGTLITLRSINLNANARPDQLVAVRVFITDKLIISTRRRKVLAIDEILTDLKEGNGPTDSGSWLVSIAESLTDHTSEFIDDLHEKIIDLEDDLLEQKIPPRGELALIRKQLIVLRRYMTPQRDVFSRISGEKLPWMQDDDRRRMQEIADRLGRGLEDLDASIARTTVLSDEITALMTEAMNRRTYTMSLLAMVFLPTTFLTGLFGVNLGGIPGGDAPFGFFTFCLMLVILVGGVAWWLKRSKWL
What is the function of this protein?
Zinc transporter.  Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake.
What are the official names of this protein?
Zinc transport protein ZntB.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y873_METJA
Sequence: MLKTENLSVGYGNYVVVEGINLEINRGEILCIIGPNGAGKSTLLKTIATYLKPKKGVVYLNGKKIHDLKPKDLAKEMAVVLTERVNPGNMTGFDVVAIGRHPYTDLFGRLTERDKKIIIESARAVNAEYLLEKNFFEMSDGERQKIMIARALAQEPKVLILDEPTSFLDAKHKIELTLLLRKLADEKNLAIVVTLHDIELALRIADKMALIKNHKVIAYGYPENVMKREIVNELYDLKNANYSEVIGYFELKNNPIKNKKIFVICGGGTGANVLRYLVKNRYDVVVGHLA
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein MJ0873.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: RH52A_ORYSJ
Sequence: MAAAAAVAKSVEAGGEPGGGGGGAWSTVSRSGRSSYSAGGGVGGGKVGELAEGLAGVEIGGERRLDKYDIPVEVSGEDVPPPADGFEAAGLVEAVLRNVARCGYESPTPVQRYSMPIALAGRDLMACAQTGSGKTAAFCLPVVSGLVAAGGSGIGHRERSSFNRAAAKPRALVLAPTRELAAQINEEAKKFSFQTGLRVVVAYGGTPMYNQLRDLERGADILVATPGRLVDMVERSKVSLEAIKYLVMDEADRMLDMGFEPQIRKIVERMNMPRKSVRQTMLFSATFPPEIQRLASDFLSNYIFITVGRVGSSTDLIMQKVELLSDGEKRGYLLDLLQRQSVGVANSKLQQPLTLVFVETKREADSLRYWLYSKGFPATAIHGDRTQQERESALRSFKTGLTPIMVATDVASRGLDVPNVAHVINYDLPKSIEDYVHRIGRTGRAGKAGSATAFFTESDHSLAKGLLELMTEAKQDVPDWLVQYAERPYYGGSSYGGRNRRSGGGGNRFAGRDFRQGSGGGYSGGGGGGGYSGGGGGGGYSGGGGGYSGGGRGGGYSRGGRGGYSGGGGGGGGDPYRASAPPPRYYPSYPMGTADINASGWD
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 52A.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.
Protein: GSTM3_HUMAN
Sequence: MSCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.  May govern uptake and detoxification of both endogenous compounds and xenobiotics at the testis and brain blood barriers.
What are the official names of this protein?
Glutathione S-transferase Mu 3, GST class-mu 3, GSTM3-3, hGSTM3-3.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Mu family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRP41_PYRAR
Sequence: MKKPPVPLLQNGVRADGRLPDQMREVKISVGVVSNADGSAMVSYGATTAVAAVYGPREMHPRHLSLPDRGVMRVRYHMAPFSTKDERKSPTPSRREIEISKVLREALEPAVLLEQYPRSRIDVFIEIIQADGSTRVASLTAASLALADAGIYMRDLVVGVSVGLVDGVVVLDLNGLEDNYGEGDLPVGYMPNLKRFVLLQLDGAWKREVFLQALNLAVKGAEYVYQIARDALKNKYMSIAEEIYGR
What is the function of this protein?
Catalytic component of the exosome, which is a complex involved in RNA degradation.  Has 3'->5' exoribonuclease activity.  Can also synthesize heteromeric RNA-tails.
What are the official names of this protein?
Exosome complex component Rrp41.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family. Rrp41 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUT10_MOUSE
Sequence: MVRFQRRKLLASCLCVTATVFLMVTLQVVVELGKFERKKLKDSNVQDGHRDVEGEPKHLEPFPEKEALALAGRTKVDAGSYPIVLWWSPLTGETGRLGQCGADACFFTINRTFQHHPMTRAFLFYGTDFNIDSLPLPREAHHDWALFHEESPKNNYKLFHKPVITLFNHTATFSRHSHLPLTTQYLEGVDVLKSLRYLVPLQAKNNLRQKLAPLVYVQSDCDPPSDRDSYVRELMAYIEVDSYGECLQNRDLPQQLKNPASMDADAFYRVIAQYKFILAFENAVCDDYITEKFWRPLKLGVVPVYYGSPTIADWLPSNRSAILVSEFSHPRELASFIRRLDYDDGLYETYVEWKLKGKISNQRLLTALNEREWGVQDINQDNYIDSFECMVCRRVWANSRLQEQGLPPKQWKADVSHLHCPEPALFTFSSPASPALRGRSLRELWLPSFQQSKKEAQALRWLVDRNQNFSSEEFWALVFKD
What is the function of this protein?
Predominantly fucosylates the innermost N-acetyl glucosamine (GlcNAc) residue in biantennary N-glycan acceptors.  Postulated to generate core alpha(1->3)-fucose epitope within the chitobiose unit of biantennary N-glycans, providing for a recognition signal to reorient aberrantly folded glycoproteins for degradation (By similarity).  Involved in biosynthesis of Lewis X-carrying biantennary N-glycans that regulate neuron stem cell self-renewal during brain development (PubMed:23986452).
What are the official names of this protein?
Alpha-(1,3)-fucosyltransferase 10, Fucosyltransferase X, Fuc-TX, FucT-X, Galactoside 3-L-fucosyltransferase 10, Fucosyltransferase 10.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 10 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: NNR_HYPBU
Sequence: MLGRPVFGLGKAITSVDVAVIDANSEWIGVKRLQLMENAGRSVAEEAAKLAKPGSRVVVFAGPGGNGGDGLVAARHLAYMGYQVTVVMIVKPEEIRSPETRAMYEALAAMDLTVDIRIARAPADVAPVEADVVIDALLGTGLRGAPRPPYSDAIEAVNSSTGLKLAVDVPSGLNSDTGETPGAYVKADITVTFHKPKPGLLRRPDVAGRLVVVSIGAPPEAEVYVGPGDVAYRVRPRSWKAHKGSSGRVLIVGGSQDYVGAPILAALAAERSGVDLVFLAAPEHVTRAASHHPTIIPVPLRGSPNIHPDHVKKLEQLLDRVDAIAIGMGVGLSDETKEAIPQIIVKALEKEKPVVVDADGIKILGERGIPNSNRKLVVTPHQREFQILFGDALSGVDEDIKARALKAAEKAQRHGLVILLKGPIDIVTDGERIRLNRTGVPAMSVGGTGDTLAGITAALLARKLEPFHAASIAAFVNGLAGALAYAEKKDSMTAMDLIEKIPEALNNPIEAANRVPAYQRLVRGRIEWQPPVGRSES
What is the function of this protein?
Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP.  This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity).
What are the official names of this protein?
Bifunctional NAD(P)H-hydrate repair enzyme Nnr, Nicotinamide nucleotide repair protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NnrD/CARKD family.
Protein: ASSY_STRCO
Sequence: MSKVLTSLPTGERVGIAFSGGLDTSVAVAWMRDKGAVPCTYTADIGQYDEPDIASVPDRAKTYGAEVARLVDCRAALVEEGLAALTCGAFHIRSGGRAYFNTTPLGRAVTGTLLVRAMLEDDVQIWGDGSTFKGNDIERFYRYGLLANPQLRIYKPWLDADFVTELGGRKEMSEWLVAHDLPYRDSTEKAYSTDANIWGATHEAKTLEHLDTGVETVEPIMGVRFWDPSVEIAPEDVTIGFDQGRPVTINGKEFASAVDLVMEANAVGGRHGMGMSDQIENRIIEAKSRGIYEAPGMALLHAAYERLVNAIHNEDTLAQYHTEGRRLGRLMYEGRWLDPQSLMIRESLQRWVGSAVTGEVTLRLRRGEDYSILDTTGPAFSYHPDKLSMERTEDSAFGPVDRIGQLTMRNLDIADSRAKLEQYAGLGLIGTANPAIGAAQAAATGLIGAMPEGGAQAIASRGEVSADDELLDRAAMESGTD
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VKTH6_BUNMU
Sequence: MSSGGLLLLLGLLRVCAELTPVSSKDPYCNLPPDPGPCHDNKFAFYHHPASNKCKEFVYGGCGGNDNRFKTRNKCQCTCSEYP
What is the function of this protein?
Beta-bungarotoxins are presynaptic neurotoxins of the venom.  The B chain is homologous to venom basic protease inhibitors but has no protease inhibitor activity and blocks voltage-gated potassium channels (Kv) (By similarity).
What are the official names of this protein?
Kunitz-type serine protease inhibitor homolog beta-bungarotoxin B6 chain.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLPQ_BACSU
Sequence: MRKNRILALFVLSLGLLSFMVTPVSAASKGNLLSPDRILTVAHRGASGYVPEHTILSYETAQKMKADFIELDLQMTKDGKLIVMHDEKLDRTTNGMGWVKDHTLADIKKLDAGSWFNEAYPEKAKPQYVGLKVPTLEEVLDRFGKHANYYIETKSPDTYPGMEEKLIASLQKHKLLGKHSKPGQVIIQSFSKESLVKVHQLQPNLPTVQLLEAKQMASMTDAALEEIKTYAVGAGPDYKALNQENVRMIRSHGLLLHPYTVNNEADMHRLLDWGVTGVFTNYPDLFHKVKKGY
What is the function of this protein?
Glycerophosphodiester phosphodiesterase hydrolyzes glycerophosphodiesters into glycerol-3-phosphate (G3P) and the corresponding alcohol (PubMed:27780866).  Involved in wall teichoic acid (WTA) metabolism during phosphate starvation (PubMed:27780866).  Catalyzes the degradation of WTA, enabling the utilization of WTA as a phosphate reserve under limiting conditions (PubMed:27780866).  Is highly selective for the poly(gylcerol phosphate) WTA backbone and catalyzes exolytic cleavage of individual monomer units (PubMed:27780866).  In vitro is active toward the WTA oligomer mimics glycerophosphoglycerol (GPG) and bis-glycerophosphoglycerol (bGPG) (PubMed:27780866).
What are the official names of this protein?
Glycerophosphodiester phosphodiesterase, Glycerophosphoryl diester phosphodiesterase, Teichoicase.
What is the protein family that this protein belongs to?
Belongs to the glycerophosphoryl diester phosphodiesterase family.
Protein: CBR4_XENTR
Sequence: MTKVCAVFGGSRGIGKAVSKLLAQRDYKVAVISRDLEVAKAAAAEVGAHLALSCDVSKENEIQDTFKEITNNLGNVDYLVNSAGIRRDALLLRTRSEDIRSLLSVNLVGTIQTCKLALRSMIQQQGGAIVNIGSIVGHKGNIGQSIYGASKEGLIGFSKSLAKEVAKRNIRVNVVAPGFIHTDMTLGLEEDSLTKMVPLGRFGDPEEVAQSVLFLLESPYITGHVLVVDGGLQLQM
What is the function of this protein?
The heterotetramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis.  Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD.  The homotetramer has NADPH-dependent quinone reductase activity.  Both homotetramer and the heterotetramer have broad in vitro substrate specificity and can reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones.
What are the official names of this protein?
Carbonyl reductase family member 4, 3-ketoacyl-[acyl-carrier-protein] reductase beta subunit, KAR beta subunit, 3-oxoacyl-[acyl-carrier-protein] reductase, Quinone reductase CBR4.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: Y1253_ARCFU
Sequence: MREIKIVLPELEDVVPEEFLEHMLKATKEILLAMRTLIDSGLDKIEAVEEITKAKKEIKKIEVE
What are the official names of this protein?
Uncharacterized protein AF_1253.