PharMolix/UniProtQA huggingface dataset:
Protein: RL17_ECO8A
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKELRRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGFRAGDNAPMAYIELVDRSEKAEAAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: ATB_ARATH
Sequence: MEEVTRSVLAEEILKRLDLENLCSVACVSTTLRSAVVSGVLPSLTSLDLSVFSPDDETLNHVLRGCIGLSSLTLNCLRLNAASVRGVLGPHLRELHLLRCSLLSSTVLTYIGTLCPNLRVLTLEMADLDSPDVFQSNLTQMLNGCPYLESLQLNIRGILVDATAFQSVRFSLPETLKALRLQPLLESEAILLMNRFKVTGTYLSQPDYNSALLSPSPSFTLQSLSLVLDLISDRLIIAITGSLPQLVKLDLEDRPEKEPFPDNDLTYTGLQALGFCQQLTSLSLVRTCYNRKISFKRINDMGIFLLSEACKGLESVRLGGFPKVSDAGFASLLHSCRNLKKFEVRGAFLLSDLAFHDVTGSSCSLQEVRLSTCPLITSEAVKKLGLCGNLEVLDLGSCKSISDSCLNSVSALRKLTSLNLAGADVTDSGMLALGKSDVPITQLSLRGCRRVSDRGISYLLNNEGTISKTLSTLDLGHMPGISDRAIHTITHCCKALTELSIRSCFHVTDSSIESLATWERQAEGGSKQLRKLNVHNCVSLTTGALRWLSKPSFAGLHWLGMGQTRFAGRKETVTAMICGQRPWLTLCFDGCELGCSDGWEFHTPQRH
What are the official names of this protein?
F-box protein At-B.
Protein: MURB_SHISS
Sequence: MNHSLKPWNTFGIDHNAQHIVCAEDEQQLLNAWQHATAEGQPVLILGEGSNVLFLEDYRGTVIINRIKGIEIHDEPDAWYLHVGAGENWHRLVKYTLQEGMPGLENLALIPGCVGSSPIQNIGAYGVELQRVCAYVDCVELATGKQVRLTAKECRFGYRDSIFKHEYQDRFAIVAVGLRLPKEWQPVLTYGDLTRLDPTTVTPQQVFNAVCHMRTTKLPDPKVNGNAGSFFKNPVVSAETAKALLAQFPTAPNYPQAGGSVKLAAGWLIDQCQLKGMQMGGAAVHRQQALVLINEDNAKSEDVVQLAHHVRQKVGEKFNVWLEPEVRFIGASGEVSAVETIS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_BART1
Sequence: MELRSNNSTITAPKPKGIIDPNTGELIGSDDRFFRDINAELSDKGFLVTSADALITWARTGSLMWMSFGLACCAIEMMQCSMPHYDNERFGYAPRASPRQSDVMVVAGTLTNKMAPALRKVYDQMPEPRYVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILLLQKKIRRTGSIER
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DEN11_RAT
Sequence: MVEQGDAAPLLRWAEGPAVSVPQDPALQAGGWVRGGSGGGRVAAEAPRRREPEEPAPPEVLLQPGRLELGDVEEDQVVAVFVVTFDPRSGNMVEWCLPQDIDLEGVEFKSMASGSHKVQSDFIYFRKGPFFGLACFANMPVESELERGARMKSVGILSPSYTLLYRYMHFLENQVRHQLEMPGHYSHLAAFYEDKKGVLHAGPGRGGSLPPVYWLPSIHRYMYPEMKITHPAGCMSQFIKFFGEQILILWKFALLRKRILIFSPPPVGVVCYRVYCCCCLANVSLPGIGGTIPESKPFFYVNVADIESLEVEVSYVACTTEKIFEEKRELYDVYVDNQNVKTHHDHLQPLLKLNSADREKYRRLNEQRQMLLYSQEVEGDYSPCEEDLFVLFFLEQNNRIFQTLLEVSASQDKTLTAEHARGMGLDPQGDRSFLMDLLEAYGIDVMLVIDNPCCP
What is the function of this protein?
Probable guanine nucleotide exchange factor (GEF).  May promote the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bound form (Probable).  May play a role in neuritogenesis, as well as in neuronal recovery and/or restructuring in the hippocampus following transient cerebral ischemia.
What are the official names of this protein?
DENN domain-containing protein 11, DENND11, Protein LCHN.
What is the protein family that this protein belongs to?
Belongs to the DENND11 family.
Protein: OBG_HAEIE
Sequence: MKFIDESLIRIEAGDGGNGCVSFRREKFIPKGGPDGGDGGDGGDVYLQADENLNTLIDYRFNKRFAAERGENGRSSDCTGRRGKDIILPVPVGTRAIDNDTKETLGDLTQHGQKMLVAKGGYHGLGNTRFKSSVNRAPRQKTMGTPGEKRDLLLELMLLADVGMLGFPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVKVDDSHSFVVADIPGLIEGAADGAGLGIRFLKHLERCRVLIHLVDIAPIDGSNPADNVAIIESELFQYSEKLSEKPRWLVFNKIDTMSDEEAEERVREITEQLGWEEDYYLISAATGKNVPPLCRDIMDFIIANPREAETQQVAPEEVKFKWEDYHQEQLAEYQFDDDEDWDDDWTEEDDDEDWDDDWTEEDDEGIEFIYKP
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_RHORT
Sequence: MSAAKIKKGDKVVVLAGKDKGKRGEVLKAIPKEGRVVVQGVNVVKRHTRPTNTAAGGIVEKEASIHVSNVAHEDPKDGSPTRVGFKVLEDGRKVRYAKRSGDVIDG
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: Y899_CHLAA
Sequence: MTSPAKSSTAASSSSQRSLSAWSPLGGERFYAAARWVLIILLGVVTQFLTNGGLWPVTDEIGPLEGIFWLYVGFALVFTVLAFLQFAAGLVSISYLFDIAFISLMTFFGGERIVIFFPLYLVPLTYAAIRQSRSVSLLSGLLAAVAYMAAFIAWRRLIAPEALMTLLDYVALALRGTTLAIVPWVTGNLAERQSEFNRERVTQAQRDAEQALSEARAYRDQMRSLYRVALTLGSTANYRQVLDTLLQESQKIVPYRAGIVLLSSGQPNELYVAFGSNLAPGDLNRSLKMDTGLAAALRANTAQVITSFTQFPSLQQLGSLRTCKAAALLPLQAGMRVYGLFVVATDQTLTTDQVEMLMALANYAIVALHNAQLIYDLKEEREKLLSHEEEVRHQLARDLHDGPAQAMAVITMKAEFIKRLLERDPAQALAELDELSSIAKRTNYEVRTMLFELRPLMLETQGLKVTLEQYLDRLRAKAGNTAIVLEGTDIDKVRLGSKVEGALFNMIQESVTNAIKHAKANHIWVRLRRLNDQMLEVVIQDDGVGFDKAAVLKSYERRGSFGLLNIDERARLVGGRAEIDSTPGKGTQITIFVPIES
What are the official names of this protein?
Uncharacterized sensor-like histidine kinase Caur_0899.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PA2TI_NAJHH
Sequence: NVYQYRKMLQCAMPNGGPFECCQTHDNCYGEAEKLKACTSTHSSPYFK
What is the function of this protein?
Phospholipase A2 with weak enzymatic activity, which partially inhibits thrombin enzymatic activity (Ki=73 nM), completely inhibits thrombin-induced platelet aggregation and retards fibrin clot formation (IC(50)=0. 2 nM) (PubMed:19622365).  May exert this anticoagulant effect through a non-enzymatic mechanism (PubMed:19622365).
What are the official names of this protein?
Phospholipase A2 TI-Nh, svPLA2, Phosphatidylcholine 2-acylhydrolase, Thrombin inhibitor from Naja haje.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NFYB_MOUSE
Sequence: MTMDGDSSTTDASQLGISADYIGGSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYLPIANVARIMKNAIPQTGKIAKDAKECVQECVSEFISFITSEASERCHQEKRKTINGEDILFAMSTLGFDSYVEPLKLYLQKFREAMKGEKGIGGAVSATDGLSEELTEEAFTNQLPAGLITADGQQQNVMVYTTSYQQISGVQQIQFS
What is the function of this protein?
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.  NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.
What are the official names of this protein?
Nuclear transcription factor Y subunit beta, CAAT box DNA-binding protein subunit B, Nuclear transcription factor Y subunit B, NF-YB.
What is the protein family that this protein belongs to?
Belongs to the NFYB/HAP3 subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GRP3_DAUCA
Sequence: MGGGDGHNDQDKGLFSNLAGGLAGGGHYPPGQYPPAAGGYPPQGYPPAGGGYPPQGYPPAGGGYPPQGYPPAGGGYPPQGYPPAGHHSGSSAPHHSGHGGVAGMVAGGRAAAAAAYGVHHMTQGHGSHGGHGGYAHGAMGMMPGMGAMAMASSSTVSTVMESLSRESTGRARSTDTRSGSNLSFSISSRTFWATK
What are the official names of this protein?
Glycine-rich protein A3.
Protein: ARGB_ALIB4
Sequence: MAQTNPKVQTLIDAIPYFKKFYGKTIVIKYGGSAQTSDDLKEKFAQDIVLLTLLGIKPVVVHGGGARITELLNKLEIPSSFVDGYRVTCKESMRVVEMVLSGEINKNIASLLNFHGAKAIGISGKDSGIIKAVPKDGGKFGYTGDITSVNGELINNLIKEGFIPVIAPIANGDEANHPGFNINADVAACEIAMALKAQKVIFLTDTIGVLNKSGELIQTLDKANVEMFKKDGTIAGGMIPKVDSCIEAIHNGVNKAHIIDGRVEHSILLELFTSDGIGTQFIRVDNPNNGIDIEKLLNKQD
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGO_MARH1
Sequence: MYLNLYEIKIPYRVKRLYYFNKENDPKEFARNLSRVNNIRFNDSKDLVWLEIPDIDFKITPQQAEKYKIEKNEIIGEKEDSDLFVKTIYRYIKKKFIDNNFYYKRGNNYISINDKFPLDSNTNVNAHLTYKIKLYKINERYYISVLPKFTFLSDKPALESPIKSTYLFNIKSGKTFPYISGLNGVLKIDLGENGIKEVLFPENYYFNFTSKEAEKFGFSKEIHNIYKEKIFSGYKKIKQSLYFLEDIININNYNLTMDKKIYVNIEYEFKKGISRNIKDVFKYSFYKNDQKIKIAFFFSSKKQIYEIQRSLKMLFQNKNSIFYQTIYEMGFSKVIFLREPKTNSSAFMYNPETFEISNKDFFENLEGNIMAIIILDKFLGNIDSLIQKFPENLILQPILKEKLEKIQPYIIKSYVYKMGNFIPECQPYVIRNLKDKNKTLYIGIDLSHDNYLKKSNLAISAVNNFGDIIYLNKYKNLELNEKMNLDIVEKEYIQILNEYYERNKNYPENIIVLRDGRYLEDIEIIKNILNIENIKYSLIEVNKSVNINSCEDLKEWIIKLSDNNFIYYPKTYFNQKGVEIKIIENNTDYNNEKILEQVYSLTRVVHPTPYVNYRLPYPLQVVNKVALTELEWKLYIPYMK
What is the function of this protein?
A highly versatile argonaute that uses 5'-phospho- and 5'-OH- guide RNA (gRNA) or DNA (gDNA) to cleave target RNA or ssDNA (tDNA) in all possible combinations; has no detectable activity in the absence of guide.  Uses short guide sequences (18-21 nucleotides (nt) on average) to bind complementary target nucleic acids resulting in target cleavage in a site-specific manner.  Using 5'-phospho-gRNA or 5'-OH-gRNA the cleavage site is 10 nt downstream of the target residue base-paired with the 5'-end of the gRNA, using 5'-phospho-gDNA the cleavage site is 11 nucleotides (nt) downstream, while with 5'-OH-gDNA the cleavage site is 9 nt downstream.
What are the official names of this protein?
Protein argonaute, MhAgo.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Long pAgo subfamily.
Protein: URE2_MYCTA
Sequence: MIPGEIFYGSGDIEMNAAALSRLQMRIINAGDRPVQVGSHVHLPQANRALSFDRATAHGYRLDIPAATAVRFEPGIPQIVGLVPLGGRREVPGLTLNPPGRLDR
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLRA1_BOVIN
Sequence: MYSFNTLRLYLWETIVFFSLAASKEAEAARSASKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNQ
What is the function of this protein?
Glycine receptors are ligand-gated chloride channels.  Channel opening is triggered by extracellular glycine.  Channel opening is also triggered by taurine and beta-alanine.  Channel characteristics depend on the subunit composition; heteropentameric channels are activated by lower glycine levels and display faster desensitization (By similarity).  Plays an important role in the down-regulation of neuronal excitability (PubMed:11178872).  Contributes to the generation of inhibitory postsynaptic currents.  Channel activity is potentiated by ethanol (By similarity).  Potentiation of channel activity by intoxicating levels of ethanol contribute to the sedative effects of ethanol (By similarity).
What are the official names of this protein?
Glycine receptor subunit alpha-1, Glycine receptor 48 kDa subunit, Glycine receptor strychnine-binding subunit.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Synapse. Perikaryon. Cell projection, dendrite. Cell membrane; Multi-pass membrane protein.
Protein: B2MG_PAPAN
Sequence: MSRSVALAVLALLSLSGLEAIQRTPKIQVYSRHPPENGKPNFLNCYVSGFHPSDIEVDLLKNGEKMGKVEHSDLSFSKDWSFYLLYYTEFTPNEKDEYACRVNHVTLSGPRTVKWDRDM
What is the function of this protein?
Component of the class I major histocompatibility complex (MHC).  Involved in the presentation of peptide antigens to the immune system (By similarity).
What are the official names of this protein?
Beta-2-microglobulin.
What is the protein family that this protein belongs to?
Belongs to the beta-2-microglobulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DIUH_DIPPU
Sequence: TGTGPSLSIVNPLDVLRQRLLLEIARRRMRQTQNMIQANRDFLESI
What is the function of this protein?
Regulation of fluid secretion.  Stimulates primary urine secretion by Malpighian tubules and causes a dose-dependent stimulation of cAMP levels in the tubules.  Has a greater effect on the transport of Na(+) then K(+) ions.  In vitro, has synergistic effects with the smaller diuretic hormone DH(31) which co-occurs with it.
What are the official names of this protein?
Diuretic hormone class 1, DH(46), Diuretic hormone class I, Diuretic peptide, DP.
What is the protein family that this protein belongs to?
Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
What are the subcellular locations of this protein?
Secreted.
Protein: PRG2_HUMAN
Sequence: MKLPLLLALLFGAVSALHLRSETSTFETPLGAKTLPEDEETPEQEMEETPCRELEEEEEWGSGSEDASKKDGAVESISVPDMVDKNLTCPEEEDTVKVVGIPGCQTCRYLLVRSLQTFSQAWFTCRRCYRGNLVSIHNFNINYRIQCSVSALNQGQVWIGGRITGSGRCRRFQWVDGSRWNFAYWAAHQPWSRGGHCVALCTRGGHWRRAHCLRRLPFICSY
What is the function of this protein?
Cytotoxin and helminthotoxin.  Also induces non-cytolytic histamine release from human basophils.  Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions.  The proform acts as a proteinase inhibitor, reducing the activity of PAPPA.
What are the official names of this protein?
Bone marrow proteoglycan, BMPG, Proteoglycan 2.
What are the subcellular locations of this protein?
[Bone marrow proteoglycan]: Secreted. Note=The proform is secreted. SUBCELLULAR LOCATION: [Eosinophil granule major basic protein]: Cytoplasmic vesicle, secretory vesicle. Note=The proform is secreted. The mature protein is found in the matrix of the eosinophil's large specific granule (crystalloid core).
Protein: ECFA1_MYCGE
Sequence: MLPTKQAACSFINVAFSYNELPLIRELSFSVYEGEYVCIVGHNGSGKSTISKLLTGLLKPQAGEIKIFGKTVDFDNVSYLRNNIGIIFQNPDNQFIGITVEDDIAFGLENKCFSRQKIKAIIDEVTLQTQTDGFIKQEPHNLSGGQKQRVAIASVLALNPAIIIFDESTAMLDPKAKKTIKQFMVKLAKQGKCVISITHDMEEVTKADKVLVMNEGKLIKQGKPVEVFTSEQELQKIRLDIPFSLSLSTKIRGITSTIDYQTLIKSIAKLWKKR
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA1, ECF transporter A component EcfA1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SYFB_LEGPL
Sequence: MKVSKLWLREWVNFSLTEQELAEQLTMAGLEVDAVNPVAGQFTHVIVAEVLNTKPHPDADKLTLCEVNINKDKPLKIVCGAANVRPGLRVALAMIGAHLPGGLQIKESKLRGELSQGMLCSATELGLAEHSEGIMELSDEAPIGMDLREYLALDDHVFDIDLTPNRADCFSILGVAREVAVLNKLPLIEQPIVTVPPAIDDGLRVNLIHSEACPRYCGRIIRNLNLEAKTPLWMAERLRRGGIRTLHPVVDVMNYVMLELGQPMHAFDLSKINGEINVRYSASGEQLELLDGQEVVLNDNVLVIADKEKPLAMAGIMGGANSAVQEQTQHIFLESAYFNPVTIAGVARKYGLFSDSSQRFERGVDPCLQSKALERATELILSISGGEPGPVIESFDKKFLPGTVSFLFDTTKVKKLTGLSIPLNEMKNLLEGLGVVIIKETNHFFEVTIPSHRVDLQQDADLVEEIIRLYGYDKLQAQPMQTSVQAGLISAKEKIATHVSSWFSAKGYHETISYSFVDPELQEALYPQKEFMELLNPISSELSQMRAGMWPGLIASMIYNSHRQQTAVKFFEIGVVFDLDGGQLKERSCIAGLLMGEQGNLNWSESARLFDFYDLKGDLQSLFASLKLDDVEFIQSSHHALHPGQSAQIVINGKHSGWIGVLHPRLSDAFDLDQDVVLFELNLESLINPTIPLYKPISKYPQIRRDLSFLVDRQISAMQIERVIRNTVKEDWLKSFDVFDVYMGKGIPEDKKSIAVAMTLQDDTRTLVDAEINLTISAIIKKLENEFSILLRE
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATMC_SCHPM
Sequence: MDSHQELSAGSPISYDFLDPDWCFKRYLTKDALHSIETGKGAAYFVPDGFTPILIPNSQSYLLDGNSAQLPRPQPISFTLDQCKVPGYILKSLRKDTTSTERTPRPPNAFILYRKEKHATLLKSNPSINNSQVSKLVGEMWRNESKEVRMRYFKMSEFYKAQHQKMYPGYKYQPRKNKVKR
What is the function of this protein?
Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion.  Positive regulator of MFM genes.  The HMG box recognizes the DNA sequence 5'-AACAAAG-3'.  Required for conjugation and efficient meiosis.
What are the official names of this protein?
Mating-type M-specific polypeptide Mc, mat-Mc.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein: RPOC_CORA7
Sequence: MFDVNLFDELRIGLATAEDIRRWSKGEVKKPETINYRTLKPEKDGLFCERIFGPTRDWECACGKYKRVRYKGIICERCGVEVTKSKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAPKDLERIIYFAANIITSVDEEARHNDQSTLEAEMLLEKKDVEDDVEAEIAERAAKLEQDLAELEAAGAKADARRKVQNAADKEMQHIRERGEREVARLDEIWNTFIKLAPKQMIIDETIYEELVDRYEDYFTGGMGAEAIQTLIRNFDLEAEAEELKEIINNGKGQKKMRALKRLKVVAAFLRSGNDPAGMVLDAIPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRMIDLGAPEIIVNNEKRMLQESVDALFDNGRRGRPVTGPGNRPLKSLSDLLKGKQGRFRQNLLGKRVDYSGRSVIIVGPQLKLHECGLPKLMALELFKPFVMKRLVENDYAQNIKSAKRMVERQRPEVWDVLEEAISEHPVMLNRAPTLHRLGIQAFEPKLVEGKAIQLHPLACEAFNADFDGDQMAVHLPLSAEAQAEARVLMLASNNILSPASGKPLAMPRLDMVTGLYYLTMDKGEDEIGGEGRYQPATEDRPEQGVYSSYAEAIMARDRGVLGLQAPIKVRISHLRPPSDIEAEQFPDGWQKGQAWLAETTLGRIMFNDLLPWNYPYLEGVMVRKGGAGNKMLLGDVINDLAAKYPMITVAQVLDKMKDAGFYWATRSGVTITMHDVLVLPNKTEVLESYEKEAERIERKYWEQGALTERERYDRLVELWKDATDTVGNAVEEMYPDDNPIPMIVKSGAAGNMRQIWTLAGMKGMVVNSKGDYITRPIKTSFREGLSVLEYFNNSHGSRKGLADTALRTADSGYLTRRLVDVAQDVIVREEDCGTRQGVRVPLGIEVAPGSYDLHELWETSASGRVVANDVKDENGEVIAEAGTDLTEELSRTIVNAGVLEIKVRSVLTCQTPAGVCAKCYGKSMASGQLVDIGEAVGIVAAQSIGEPGTQLTMRTFHQGGVGGDITGGLPRVQELFEARNPKNRAPIASVDGTVSLSDEGNFWTLTITPDDGSDNVVYEKLSKRQGLAQVRRPMESNPDAMIERSLRDGDHVSTGDRLMRGAPDPHDVLEVLGRRGVEKHLIDEVQAVYRAQGVAIHDKHIEIIIRQMLRRGTVIDAGTTDLLPGNLIDLSEAKQVNAAQVAEGGQPAQLRSEIMGITKASLATESWLSAASFQETTRVLTDAAINKRSDQLIGLKENVIIGKLIPAGTGISRYRNISVKPTEAARNAAYSIPTYGDSIYGDDGFGEFTGASVPLEEDYTF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RL29_BRUSI
Sequence: MKAADVRAKSLDQLNDELGTLKKEQFNLRFQKATGQLEKTARVKQVRRDIARIKTIARQKAAESKA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RUVA_BEII9
Sequence: MIGKLTGLVDSQGEDHVILDVQGVGYIVFCSSRTLRLLPKPGASTALLIEMQVREDAIRLFGFPSEVERDWFRLLQSVQGVGAKVALALQGLLSATELAQAIALQDKASLGRAPGVGPKLAARLITELKDKMPALGPVDSLTAKLTIAEAEGTAPVAAQDAITALVNLGYGRPQAAAAVATSLEALGETAPLADLIRRGLKELAR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: CABP2_HUMAN
Sequence: MGNCAKRPWRRGPKDPLQWLGSPPRGSCPSPSSSPKEQGDPAPGVQGYSVLNSLVGPACIFLRPSIAATQLDRELRPEEIEELQVAFQEFDRDRDGYIGCRELGACMRTLGYMPTEMELIEISQQISGGKVDFEDFVELMGPKLLAETADMIGVRELRDAFREFDTNGDGRISVGELRAALKALLGERLSQREVDEILQDVDLNGDGLVDFEEFVRMMSR
What is the function of this protein?
Required for sound encoding at inner hair cells (IHCs) synapses, likely via inhibition of the inactivation of voltage-gated calcium channel of type 1. 3 (Cav1. 3) in the IHCs (PubMed:28183797).  Required for the normal transfer of light signals through the retina (By similarity).
What are the official names of this protein?
Calcium-binding protein 2, CaBP2.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus.
Protein: RL19_LIMRJ
Sequence: MRQNKLIEKITASQLRDDIPEFRAGDTVRVHARIVEGSRERIQMFEGVVIKRHGAGISATYTVRKISNGVGVERTFPVHSPRVDKIDVLRYGRVRRAKLYYLRERTGKATRIAERRRDN
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: COQ3_HUMAN
Sequence: MWSGRKLGSSGGWFLRVLGPGGCNTKAARPLISSAVYVKNQLSGTLQIKPGVFNEYRTIWFKSYRTIFSCLNRIKSFRYPWARLYSTSQTTVDSGEVKTFLALAHKWWDEQGVYAPLHSMNDLRVPFIRDNLLKTIPNHQPGKPLLGMKILDVGCGGGLLTEPLGRLGASVIGIDPVDENIKTAQCHKSFDPVLDKRIEYRVCSLEEIVEETAETFDAVVASEVVEHVIDLETFLQCCCQVLKPGGSLFITTINKTQLSYALGIVFSEQIASIVPKGTHTWEKFVSPETLESILESNGLSVQTVVGMLYNPFSGYWHWSENTSLNYAAYAVKSRVQEHPASAEFVLKGETEELQANACTNPAVHEKLKK
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, mitochondrial, 3-demethylubiquinol 3-O-methyltransferase, Polyprenyldihydroxybenzoate methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: APT_VIBCH
Sequence: MTTETLSLIKSSIKSIPDYPKKGILFRDVTSLLEDAQAYQATIQLLVEKYKDMGFTKVVGTEARGFLFGAPLALELGVGFVPVRKPGKLPRQTVAQSYELEYGTDTLEIHVDAIKPGDKVLVVDDLLATGGTIEATTKLIRQLGGEVEHAAFVINLPEIGGDKRLEGLGLQVYSICEFEGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.