PharMolix/UniProtQA huggingface dataset:
Protein: LAC14_ARATH
Sequence: MEFKLNIPNTIIKTLQTIVFFLFVLLAFQIAEAEIHHHTFKIKSKAYTRLCNTNKILTVNGEFPGPTLKAYRGDKLIVNVINNANYNITLHWHGARQIRNPWSDGPEYVTQCPIRPGESYVYRIDLKVEEGTIWWHAHSQWARATVHGAFIVYPKRGSSYPFPKPHREIPLILGEWWKKENIMHIPGKANKTGGEPAISDSYTINGQPGYLYPCSKPETFKITVVRGRRYLLRIINAVMDEELFFAIANHTLTVVAKDGFYLKHFKSDYLMITPGQSMDVLLHANQRPNHYFVAARAYSSAFGAGFDKTTTTAILQYKGDTLNRIKPILPYLPPYNRTEASTRFTNQFRSQRPVNVPVKINTRLLYAISVNLMNCSDDRPCTGPFGKRFSSSINNISFVNPSVDILRAYYRHIGGVFQEDFPRNPPTKFNYTGENLPFPTRFGTKVVVLDYNSSVELILQGTTVWASNIHPIHLHGYNFYVVGSGFGNFDRRKDPLRYNLVDPPEETTVGVPRNGWTAVRFVANNPGVWLLHCHIERHATWGMNTVFIVKDGPTKSSRMVKPPPDLPSC
What is the function of this protein?
Lignin degradation and detoxification of lignin-derived products.
What are the official names of this protein?
Laccase-14, Benzenediol:oxygen oxidoreductase 14, Diphenol oxidase 14, Urishiol oxidase 14.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: T2H3_HAEAE
Sequence: MSNKSNDNGRAYEFAFINELGRIATQNQNINIEKNSSYYVVEKSWSTLSDLEKEKYTKSAIAGINLITSLEPIIEDGNGVLNLKIQADNKGELGDIRDILIQRENINWEIGLSLKHNHFAVKHSRLSHKIDFSEKWFQLPSSQNYWDNILPIFEKLEIYKKDKIKWRELSNKEDCIYYPILKSFIAEIKEKYDKYNSIVPQRMVEYLLGYFDFYKIISQDNKKLTSIQSFNLRGTLNKPSKKRKADIFIPVANLPTRIIDIDFKPNSKNTVELYLDKGWQFSFRIHNASTIIEPSLKFDIKLIGVPATIICLETPWEE
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-GGCC-3' and cleaves after G-2.
What are the official names of this protein?
Type II restriction enzyme HaeIII, R.HaeIII, Endonuclease HaeIII, Type-2 restriction enzyme HaeIII.
Protein: DPOLX_ASFWA
Sequence: MLTLIQGKKIVNDLRSRLAFEYNGQLIKILSKNIVAVGSLRREEKMLNDVDLLIIVPEKKLLKHVLPNIRIKDFSFSIKVCGERKCVLFIEWKKNTYQLDLFTALAEEKPYAVLHFTGPVSYLIRIRAALKKKNYKLNQYGLFKNQTLVPLKITTEKELIKELGFTYRIPKKRL
What is the function of this protein?
Error-prone polymerase lacking a proofreading 3'-5' exonuclease which catalyzes the gap-filling reaction during the DNA repair process (By similarity).  Specifically binds intermediates in the single-nucleotide base-excision repair process (By similarity).  Also catalyzes DNA polymerization with low nucleotide-insertion fidelity (By similarity).  Probably acts as a strategic DNA mutase, which gives rise to a rapid emergence of variants (By similarity).  Generates mismatched G-G pairs, in that case, the polymerase first binds the deoxynucleotide followed by mismatch formation (By similarity).  Together with the viral DNA ligase, fills the single nucleotide gaps generated by the AP endonuclease (Probable).  Binds DNA with high affinity via the helix alphaE (By similarity).
What are the official names of this protein?
Repair DNA polymerase X, Pol X, AsfvPolX.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-X family.
What are the subcellular locations of this protein?
Virion. Note=Found in association with viral nucleoid.
Protein: HIS2_HYDCU
Sequence: MSNDILLQLDKILDARKTESPETSYVASLYEKGLDKILKKVGEEATETVMAAKDAEYTQNNDNLVYEVADLWFHTLILLSHQGLSSTDITNELQKRFGLSGHEEKANRSKNDA
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR11_BRADI
Sequence: MAKAVPKIGSRKRVRIGLRRNARFSLRKSARRITKGVIHVQASFNNTIITVTDPQGRVVFWSSAGTCGFKSSRKASPYAGQRTAVDAIRTVGLQRAEVMVKGAGSGRDAALRAIAKSGVRLSCIRDVTPMPHNGCRPPKKRRL
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HFLD_PSEA7
Sequence: MSDSRQQLIALGAVFESAALVDKLARTGQISEAPLGCMLGSLLARNPASTLDVYGGDTLNLRDGFKALASALERKPGSLQREPLRYALAMLTLERQLDKRGDMLDLIGQRLDQVEQQVQHFGLVHENVIASFASIYQDTLSTFRQRIQVHGDMRHLQVSSNAARIRALLLAGIRSARLWRQLGGSRWQMVFSRRRLLNELYLLLRG
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ENV_SIVSP
Sequence: MGCLGNQLLIALLLLSASGIYCVQYVTVFYGIPAWRNATVPLFCATKNRDTWGTTQCLPDNGDYSELAINVTEAFDAWDNTVTEQAIEDVWNLFETSIKPCVKLTPLCITMRCNKSETDRWGLTGTPAPTTTQTTTTQASTTPTSPITAKVVNDSDPCIKINNCTGLEQEPMVSCKFNMTGLKRDKKREYNETWYSRDLVCEQNSNETDSKCYMNHCNTSVIQESCDKHYWDAIRFRYCAPPGYALLRCNDSNYSGFAPNCTKVVVSSCTRMMETQTSTWFGFNGTRAENRTYIYWHGRSNRTIISLNKYYNLTMRCRRPGNKTVLPVTIMSGLVFHSQPINERPKQAWCWFGGEWKKAIQEVKETLVKHPRYTGTNKTEQIKLTAPGGGDPEVTFMWTNCRGEFLYCKMNWFLNWVENIQNGSRWTSQNQKERQRRNYVPCHIRQIINTWHKVGKNVYLPPREGDLTCNSTVTSLIAEIDWINGNETNITMSAEVAELYRLELGDYKLVEITPIAFAPTSVKRYTTTGASRNKRGVFVLGFLGFLATAGSAMSAASVTLSAQSRTLLAGIVQQQQQLLDVVKRQQELLRLTVWGAKNLQTRVTAIEKYLKDQAQLNSWGCAFRQVCHTTVPRPNDTLTPNWNNMTWQEWEKQVNFLEANITQSLEEAQIQQEKNTYELQKLNSWDIFGNWFDLTSWIKYIQYGVLIVLGVIGLRIVIYVVQMLARLRQGYRPVFSSPPAYVQQIPIQTGQELPTKEGEEGDGGGRGGNRSWPWQIEYIHFLIRQLIRLLTWLFSSCRDWLLRNCQTLQPVLQSLSRTLQRAREVIRVQIAYLQYGWRYLQEAAQAWWKFVRETLASAWRDLWETLGRVGRGILAIPRRIRQGLELTLL
What is the function of this protein?
The gp120-gp41 heterodimer allows rapid transcytosis of the virus through CD4 negative cells such as simple epithelial monolayers of the intestinal, rectal and endocervical epithelial barriers.  Both gp120 and gp41 specifically recognize glycosphingolipids galactosyl-ceramide (GalCer) or 3' sulfo-galactosyl-ceramide (GalS) present in the lipid rafts structures of epithelial cells.  Binding to these alternative receptors allows the rapid transcytosis of the virus through the epithelial cells.  This transcytotic vesicle-mediated transport of virions from the apical side to the basolateral side of the epithelial cells does not involve infection of the cells themselves (By similarity).
What are the official names of this protein?
Envelope glycoprotein gp160, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein gp41]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Surface protein gp120]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Host endosome membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag (By similarity).
Protein: GAG_AVEV2
Sequence: DPITAALSQRAMVLGKSGELKTWGLVLGALKAAREEQVTSEQAKFWLGLGGGRVSPPGPECIEKPATERRIDKGEEVGETTVQRDAKMAPEETATPKTVGTSCYHCGTAIGCNCATASAPPPPYVGSGLYPSLAGVGEQQGQGGDTPRGAEQPRAEPGHAGLAPGPALTDWARIREELASTGPPVVAM
What are the official names of this protein?
Gag polyprotein, Core polyprotein.
What are the subcellular locations of this protein?
[Matrix protein p19]: Virion.
Protein: CAPP_KLEP3
Sequence: MNEQYSALRSNVSMLGKVLGDTIKDALGENILDRVETIRKLSKSSRAGNEANRQELLTTLQNLSNDELLPVARAFSQFLNLANTAEQYHSISPNGEAASNPEVIARTLRKLKDQPNLNEDTIKKAVESLSLELVLTAHPTEITRRTLIHKMVEVNSCLKQLDNKDIADYEHHQLMRRLRQLIAQSWHTDEIRKYRPSPVDEAKWGFAVVENSLWEGVPNYLRELNEQLEANLGYQLPVDFVPVRFTSWMGGDRDGNPNVTADITRHVLLLSRWKATDLFLKDVQVLISELSMVECTDELRALAGAEGAQEPYRYLMKKLRTQLMETQAWLEARLKGQKLPKPAGLITQNEQLWEPLYACYKSLQACGMGIIANGELLDTLRRVKSFGVPLVRIDIRQESTRHTEALGEMTRYLGIGDYESWSEADKQAFLIRELNSKRPLLPRQWEPSEETREVLDTCKVIAEAPRGSIAAYVISMAKTPSDVLAVHLLLKEAGIGFALPVAPLFETLDDLNNANDVMTQLLNIDWYRGFIQGKQMVMIGYSDSAKDAGVMAASWAQYQAQDALIKTCEKAGIELTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKYGLPEVTISSLSLYTSAILEANLLPPPEPKAEWRDIMAELSDVSCKMYRGYVRENKDFVPYFRSATPEQELGKLPLGSRPAKRRPTGGVESLRAIPWIFAWTQNRLMLPAWLGAGAALQKVVEGGKQSELEAMCRDWPFFSTRLGMLEMVYSKADLWLAEYYDQRLVKPELWALGTELRKLLAADINVVLAIANDSHLMADLPWIAESIQLRNIYTDPLNVLQAELLHRSRQAEEAGKDPDPRVEQALMVTIAGVAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: ATPA_LEPIN
Sequence: MKIKTDEITSVLKQEILNYKKDLGVEEVGTVLEIGDGIARVFGLKNVMSGEMVEFQNGIFGQAFNLEDNSVGVVVYGNYLDIQEGFSVKRTNRILEVPVGPELLGRVVNPLGEPIDGKGPINAKLTRPVESPAPGIAMRQPVGEPMQTGIKAIDAMIPIGRGQRELIIGDRGTGKTSIALDTILNQKGTGVICVYVAIGQKASTVASTVEMLRNKGALEYTIVVSATAADPAPLQYIAPYSGCSMAEYFMYNEKKATLVVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLDDKYGAGSLTALPIIETQEGEVSAYIPTNVISITDGQIYLQSNLFASGNRPAVDVGISVSRVGSAAQIKAMKQVAGKMKLELAQFRDLEAFAQLGTELDPATQAQLDRGNRIVQMLKQPVSSPYPVEEQVVEIFAVTRGFMDKIPVAKVQEYGKYLLNTIKEQYSEVLDSIRKEKKISDEEKLGEVLSKVAEEFLRKH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FRE2_NYCIN
Sequence: GLLGTLGNLLNGLGL
What is the function of this protein?
Antimicrobial peptide with selective activity.  Is only active against Micrococcus luteus (MIMC=50 ug/ml) and not against Bacillus cereus, Escherichia coli, Leuconostoc mesenteroides, Micrococcus luteus, Pastewella haemolytica, Staphylococcus aureus, Streptococcus faecalis and Streptococcus uberis.
What are the official names of this protein?
Frenatin-2.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Frenatin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RBL_FOUSP
Sequence: DILAAFRVTPQPGVPPEEAGAAVAPESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNRGMHFRVLAKALRMSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDFLEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREASKWSPELAAACEVWKEIKFEFEAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RK22_ACOAM
Sequence: MIKKNWITTGTEARALAQNISMSAYKARRVIDQIRGRSYEETIMILELMPYRASFPILKLVYSAAANAINNMGLSEADLFISKAEVNGGTFVKKLRPRARGRSYAIKRPTCHITIVLKDKDKSLLNE
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GLPD_STAAB
Sequence: MALSTFKREHIKKNLRNDEYDLVIIGGGITGAGIALDASERGMKVALVEMQDFAQGTSSRSTKLVHGGLRYLKQFQIGVVAETGKERAIVYENGPHVTTPEWMLLPMHKGGTFGKFSTSIGLGMYDRLAGVKKSERKKMLSKKETLAKEPLVKKEGLKGGGYYVEYRTDDARLTIEVMKRAAEKGAEIINYTKSEHFTYDKNQQVNGVKVIDKLTNENYTIKAKKVVNAAGPWVDDVRSGDYARNNKKLRLTKGVHVVIDQSKFPLGQAVYFDTEKDGRMIFAIPREGKAYVGTTDTFYDNIKSSPLTTQEDRDYLIDAINYMFPSVNVTDEDIESTWAGIRPLIYEEGKDPSEISRKDEIWEGKSGLLTIAGGKLTGYRHMAQDIVDLVSKRLKKDYGLTFSPCNTKGLAISGGDVGGSKNFDAFVEQKVDVAKGFGIDEDVARRLASKYGSNVDELFNIAQTSQYHDSKLPLEIYVELVYSIQQEMVYKPNDFLVRRSGKMYFNIKDVLDYKDSIIDIMADMLDYSPAQIEAYTEEVEQAIKEAQHGNNQPAVKE
What are the official names of this protein?
Aerobic glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CALCA_CHICK
Sequence: MVMLKISSFLAVYALVVCQMDSFQAAPVRPGLESITDRVTLSDYEARRLLNALVKDFIQMTAEELEQASEGNSVTAQKRACNTATCVTHRLADFLSRSGGVGKNNFVPTNVGSKAFGRRRRSVQI
What is the function of this protein?
CGRP induces vasodilation.  It dilates a variety of vessels including the coronary, cerebral and systemic vasculature.  Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role.
What are the official names of this protein?
Calcitonin gene-related peptide, CGRP.
What is the protein family that this protein belongs to?
Belongs to the calcitonin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLMU_SULNB
Sequence: MSISVVILAAGQGTRMKSSTPKVLHTISGKPMLFHAIDAAKEISDDITVILHHQEERIQKEVEAEYENIIFHRQDAKNFPGTGGAMKGVYTRHERTLILNGDMPLIKKSSLEALTSGDADINMSIIRLEDPSGYGRVIIEDDKVVEIVEQKDCNEAQLCTQTVNAGIYAVDTALLERYIPLLRNDNAQKEYYLTDIVKMAVDEGRTVHPVYVEEEEFKGVNSKLDLARAEEIMQRRIKEALMMAGVTMCLPETIYIDCRATFEGECELENGVRIQGAAQLVNTHIKAHSVIEDSYLKNSDVGPMGRVRPGSKLVDTHIGNFVEVKKSDLNGVKAGHLSYIGDAQIGEGSNIGAGVITCNYDGKNKFRTIIGKNVFVGSDTQLVAPVCIEDDVIIAAGTTVNKDVEKGVLAISRTPMRTVKNFFYKFFGDK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_MYCS2
Sequence: MSTPSIDRGFKADVLASALPWLKQLHGKIVVVKYGGNAMTDDVLKAAFAADMVFLRNCGIHPVVVHGGGPQISAMLKRLGIEGDFKGGFRVTTPEVLDVARMVLFGQVGRELVNLINAHGPYAVGVTGEDAQLFTAVRRNVTVDGVATDIGLVGDVEHVNAGSLLDLIAAGRIPVVSTIAPDADGVVHNINADTAAAALAEALGAEKLVMLTDVEGLYTDWPDRTSLVSEIDTGALTQLLPKLESGMVPKIEACLRAVNGGVPSAHVIDGRVEHCVLVELFTDEGTGTKVVAQ
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA2_STRCO
Sequence: MAPTSTPQTPFGRVLTAMVTPFTADGALDLDGAQRLAAHLVDAGNDGLIINGTTGESPTTSDAEKADLVRAVVEAVGDRAHVVAGVGTNNTQHSIELARAAERVGAHGLLLVTPYYNKPPQEGLYLHFTAIADAAGLPVMLYDIPGRSGVPINTETLVRLAEHPRIVANKDAKGDLGRASWAIARSGLAWYSGDDMLNLPLLAVGAVGFVSVVGHVVTPELRAMVDAHVAGDVQKALEIHQKLLPVFTGMFRTQGVMTTKGALALQGLPAGPLRAPMVGLTPEETEQLKIDLAAGGVQL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase 2, HTPA synthase 2.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOK_FRAAA
Sequence: MNPANYLILSALLFTIGTVGVLVRRNAIVVFMSIELMLNAVNLTLVTFSRINGTLDGQVMAFFVMVVAAAEVVIGLAIILSIFRTRRSASVDDVNLLKY
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS21_THIDA
Sequence: MPHVKVKENEPFDVALRRFKRSIEKVGLLTELRAREFYEKPTAERKRKLAAAVKRQSKRLRSQQLPPKMY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: GRPE_DEBHA
Sequence: MQRALLSSLRRSAGIRSGVNSMRVVRPTVLAPRMSMIRFASTEASKKEGKEDKAEAQGSQEPETAAETNKEAEGAKVEVSEIDELKAKLTKKDRELADMKNHYARAIADFRNLQESTKLEKQKARDFALQKFAKDLLESVDNFDLALNAVKEDTLKNNSEVKNLYDGVDMTRNVFEKTLARHGIEKVDPIGEQFDPNQHEATFEIAQPDKEPGTVFHVQQNGYTLNSRVLRPAKVGVVKDAEN
What is the function of this protein?
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.  Seems to control the nucleotide-dependent binding of SSC1 to substrate proteins (By similarity).
What are the official names of this protein?
GrpE protein homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: HIS1_SHEPA
Sequence: MSESTRLRIAIQKSGRLSKESQKLLKSCGVKFNVNEQRLIAHSDNMPIDLLRVRDDDIPGLVMDGVVDLGIIGENVLEEEQIERQSLGKPAECVKLRELDFGACRLSLAVPNEFEYQDASSLEGLRIATSYPNLLRRYMQEQGINYRDCMLKGSVEVAPRAGLSDGICDLVSTGATLEANGLYETEVIYRSMACIIQSTQSQPDDKQALINKILSRINGVVRAKESKYILLHAPTETLEQIVALLPGAENPTVLPLNDDTNRVAIHAVSTEDLFWDTMEQLTQLGASSILVMPIEKMMG
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1A_MOUSE
Sequence: MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDTFGPGDDDEIQFDDIGDDDEDIDDI
What is the function of this protein?
Seems to be required for maximal rate of protein biosynthesis.  Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
What are the official names of this protein?
Eukaryotic translation initiation factor 1A, eIF-1A, Eukaryotic translation initiation factor 4C, eIF-4C.
What is the protein family that this protein belongs to?
Belongs to the eIF-1A family.
Protein: VL1_BPV4
Sequence: MSFWVPNSAKLYLPPPTPVTQFLDTDEFVTRTDIFYHTSTDRLLFVGHPYFRPKKRRHRCCSQMSGSQFRVFRLKFPDPNKFSFPTQDIYNPEKQRLVWAVRGIEICRGQPLGVGVTGHPSFNKFKDAENLNQNSDQKEDDRVNVCMDPKQVQLFIVGCVPCDGEHWDKAQACEPQGPGDCPPIELKNTKIQDGEMCDTGFGNMNFAALQASKSGAPLDIVDQIVKYPDFLKMGNDPYGNSMFFYAKREQMYVRHLWARAGRVGDDIPTGESGSPYFLPATGRGPLPSSVYIGSPSGSLVSSDQQIYNRPFWIQRAQGSNNGMCWNNELFVTAVDSTRGTNFSISVHTTDPEVKPQETYTATKFKHYLRHVEEWDLSLIMQLCIVNLTPESIAYLHNMNESIIENWNLGFIQPPNDIEDHYRFITSLATRCPKKTDTQVKEDPYKDLKFWDVDLTEKFTTNLNQHSLVRKFLFQIGRKATKRSAPKTVTFENTEGKKAPKRRRKNV
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: RNY_STRPD
Sequence: MVNIILLIVSALIGLILGYALISIRLKSAKEAAELTLLNAEQEAVDIRGKAEVDAEHIKKTAKRESKANRKELLLKAKEEARKYREEIEQEFKSERQELKQLETRLAERSLTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQLQVEKLEEEKKAELEKVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTVKTAKDLLAQAMQRLAGEYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVILSGFDPIRREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPDLIKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDREVEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGARNESMENYIKRLRDLEEIATSFDGVQNSFALQAGREIRIMVQPEKISDDQVVILSHKVREKIEHNLDYPGNIKVTVIREMRAVDYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ODO1_BACMK
Sequence: MTRKNTTTNPWAKFHGPNLGYVIEQYDLYVTGAGSVDPELQELFEIFGAPSFQDDVVTGDNTATHFSPQNTGNIEKILKVVQLVEQIRSFGHTLAHINPMEDAANGQSLIEKTMNELSDADLKAIPAKTVWQDAPEGIHTALDVIHRLKDVYTKSLAYEFSHIQDSEERAWLHQMVESNSLRQPLSNKKRTALLKRLTAVEGFEQFLHKTFVGQKRFSIEGVDMLVPVLDEIVSEGAKGGVEDVMIGMAHRGRLSVLAHVLEKPYSHMFAEFKHAKIEGAVANAGWTGDVKYHLGREQVVGNEEVSTRVTLANNPSHLEFVNPVVEGFARAAQENRKKSGLPEQDTTKSFVILVHGDAAFPGQGVVSETLNLSRLNAYQTGGTIHVIANNAVGFTTDSYDSRSTKYSSDLAKGFDIPIVHVNADDPEACLAAANLAIQYRTLFKKDFLIDLIGYRRYGHNEMDDPAVTQPQVYKKIKNHPTVRAIYADQLQSAGVLNADEVETITQFMQEELKAEYAQVPPADTSAATIHVKVPEVVAKGIQPIDTGVSIESLRAINEGLLSWPEGFNVYPKVKKILERRKDALEENGKIEWALAESLAFASILQEGTPIRLTGQDSQRGTFAHRHIVLHDTDTNETYSPLHRLPNINASFSVHNSPLSEAAVVGYEYGYNVFAPETLVMWEAQYGDFSNTAQALFDQYVSAGRAKWGQKSGLVLLLPHGYEGQGPEHSSARPERFLQLAAENNWTVANLTSAAQYFHILRRQASILGTEAVRPLVLMTPKSLLRHPLTLSTASQLSEGRFQPALEQENLGAKPNKVKRLVLSTGKMAIDLAAEIESGKHEYSLDEVHMVRVEQLYPFPAEKVQSIIKRFKNLEEIIWVQEEPRNMGAWHYMAPILFELAGDKVKTGYIGRPDRSSPSGGDPFAHKAEQELIVAHALDVKYNFRQDKQEIEVFSN
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.