PharMolix/UniProtQA huggingface dataset:
Protein: AFT21_ALTAL
Sequence: MQQPIVGVGHSMGGCQIATLSVTSRRMFSTMILLDPAIGPLDMGLATLGLGQLTLRRRTQWPTREDAEKALRTSFSTWDPQVLDLLIRHSIHSDKQSIEMEDGPVSLVTGRYQELVNYIKPSFIRSGKVNGQELVHQTGPVDMYHMLGLVTCSALYLCGGESTLSVPRARDLWLSRTAKLSYSKEPGETRKVDERVVPDTGHFLPMEEPKECADIIADWIEKDECIAWNCCLGKRGKTWRELSNASKEMGAEAWMEYLQSKL
What is the function of this protein?
Abhydrolase domain-containing protein; part of the gene clusters that mediate the biosynthesis of the host-selective toxins (HSTs) AF-toxins responsible for Alternaria black spot of strawberry disease by the strawberry pathotype (PubMed:18986255).  AF-toxin I and III are valine derivatives of 2,3-dyhydroxy-isovaleric acid and 2-hydroxy-isovaleric acid respectively, while AF II is an isoleucine derivative of 2-hydroxy-valeric acid (PubMed:15066029, Ref. 5, PubMed:22846083).  These derivatives are bound to a 9,10-epoxy-8-hydroxy-9-methyl-decatrienoic acid (EDA) moiety (PubMed:15066029, Ref. 5, PubMed:22846083).  On cellular level, AF-toxins affect plasma membrane of susceptible cells and cause a sudden increase in loss of K(+) after a few minutes of toxin treatment (PubMed:22846083).  The aldo-keto reductase AFTS1 catalyzes the conversion of 2-keto-isovaleric acid (2-KIV) to 2-hydroxy-isovaleric acid (2-HIV) by reduction of its ketone to an alcohol (PubMed:15066029).  The acyl-CoA ligase AFT1, the hydrolase AFT2 and the enoyl-CoA hydratases AFT3 and AFT6, but also the polyketide synthase AFT9, the acyl-CoA dehydrogenase AFT10, the cytochrome P450 monooxygenase AFT11 and the oxidoreductase AFT12 are all involved in the biosynthesis of the AK-, AF- and ACT-toxin common EDA structural moiety (PubMed:12019223, Ref. 5, PubMed:18986255).  The exact function of each enzyme, and of additional enzymes identified within the AF-toxin clusters have still to be determined (PubMed:12019223, Ref. 5, PubMed:18986255).
What are the official names of this protein?
Abhydrolase domain-containing protein AFT2-1, AF-toxin biosynthesis protein 2-1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. AKT2 hydrolase family.
What are the subcellular locations of this protein?
Peroxisome. Note=The peroxisomal location requires the C-terminal tripeptide peroxisomal targeting signal.
Protein: INS_CAPHI
Sequence: FVNQHLCGSHLVEALYLVCGERGFFYTPKAGIVEQCCAGVCSLYQLENYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
What are the official names of this protein?
Insulin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIKES_DANRE
Sequence: MFGCLVAGRLVQTDAQQVASDKFVFNLPDYEHVNHVVVFLLGTVPFPEGLGGAVYLCVPGGAAGQVWQLLGFITNEKPSAIFRISGLKAGEGSSHPFGMMDAPAAPSMAQVGVSVEGLHLLAQQTPVSSSAVSTLDSFTQFTQKMLDSLFNFTSSFALSQSQMSPNPSEMFIPASSIRRWYENFQRRLMQNPNFWKT
What is the function of this protein?
Acts as a specific nuclear import carrier for hsp70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound hsp70 proteins into the nucleus.  hsp70 proteins import is required to protect cells from heat shock damages (By similarity).
What are the official names of this protein?
Protein Hikeshi.
What is the protein family that this protein belongs to?
Belongs to the OPI10 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: RPN2_ENCCU
Sequence: MQTIRILPNIRALLRDGRESEAIDVINAHVDVVAPHIKDDLRYIKSSDPKTSLCLSKIYFVLEDYQQAIEYALRAGDLLVDDGSFYYTSIVYHMMDSADIGGDDRIRDFVLKVIGAEDVDDSLIGYLFSIKAYGLLKEALVKYISDGNDCRRLLDLLISLGEEEGCLKEIYGMLAEIGPGKKPFIFYVIDAYFYLEDVEKVKALIERLVKEDILLCYDVAFYTEDNYSPEIEVADQRVMSILSGEFKKKILGAFLLEKNLTSFKFLESIARTRTHYLGLANSLMNLGTSNDTLYRNNADIFGQSSEWAKFSEVASIGMIHLFNSNPYEILKNYLPSEVSQKEGGALMALGLIKAGTFSEEDTEYLLYFLDTEDTLTPELAYGVCLGLGLINMGSANREILNKLKELSKVDRTLLVEASVYGMGMLGLNSWSVELLEDLRTIAGETEFERVKRAVGISFSLVLMFSEEMFYDECNASNGDFKNYINELLYDKDSIMRANGVLSLGSAFVGTGRLGVISTLLPYINDGDDDVKRAAVIAIGLVCCDDRDLLVGTLEPLSENHNFFVRAAVAVVLGLFLSGTGDKVCTNILEALMYDTNSLVRQSACIGVGFITMQCNPELVPNYKRIIEKLNRLIVDKKESGAVELGAVLGRGLSEGGGRNIVFSVRNMSGITSADRIAGAVLFLHYWYWHPLISMVSLCALPTTVFCFNEDLEEEEIEIPTSSRYNNLLICLPDIKKARRFKQKPKEDKEIVIESPSVLTFGSRCTIKQREECGIDAPAILFVKKKK
What is the function of this protein?
Acts as a regulatory subunit of the 26S proteasome which degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus.  It is essential for the regulated turnover of proteins and for the removal of misfolded proteins.  The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH (By similarity).
What are the official names of this protein?
26S proteasome regulatory subunit RPN2.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CYAY_YERPA
Sequence: MNDSEFHQLADQLMLYIEETLDSFTGDSDIDYETNGGVMTLTFENGSKIVINRQEPLHQVWLATKAGGYHFNYRDGHWYCSRSGEEFLAKLSEAASAQAGENVSFG
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: CYSC_ECOLC
Sequence: MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRYFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: RL16_RHOJR
Sequence: MLIPRRVKHRKQHHPSRSGAAKGGTQVTFGDYGIQALEPAYITNRQIESARIAMTRHIKRGGKIWINIFPDRPLTKKPAETRMGSGKGSPEWWIANVKPGRVMFEMSYPNEEIAREALRRAMHKLPCKCRIVTREEQF
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: Y3918_PSESM
Sequence: MAAKVEPFWIRKTLDQLDTQEWESLCDGCGLCCLQKLEDEEDNSVYYTRIACKLLDLKTCQCSDYANRRASVPDCIQLTPGQADEFKWLPPTCGYRLVSEGKDLPLWHHLVCGDRTAVHHERISQSGRMLSEKNVAEDDWEDYLIFRAG
What are the official names of this protein?
UPF0260 protein PSPTO_3918.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: RL22_CALMQ
Sequence: MRYWSIRDEDVIDLVKRRYNVTISADQIAKARGFEFRISWKKAIETARAIRFLTIKQAEDYMEKVKDLKAPIPIKEFTRKQAHHNVPWDGWPVAKWPVKVADSFLQVLRNLESNASYRGLNIDNTVIVHASASRGMRIRNYMPRALGRATPWFQDTVNIELVAVELPAELVPKKFSWARVLKAIK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: MURI_CLOBL
Sequence: MSINDKPIGFFDSGVGGISVLKEAFKLLPKEDFLYYGDSKNAPYGTKKVEEVKALTFNATDFLMNKGIKALVVACNTATSVTINDLRENYDIPIIGIEPALKPAVELNKGGKIIIMATPMTLAEKKFANLMDLYKETEDIEPLPCPGLPELIEQGIVSGDVIYNYLKDKFSKYDNEKISSIVLGCTHYPFIEETLKEVTHNKACIIDGSFGTSRELKRQLKNSNMLREENRVGKVTIFNSREDKDIIDLSYKLFNMK
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: COAD_WOLPM
Sequence: MNINDKIGIYPGTFDPITFGHLDIIKRACKLVDKLIIGVAENVNKHTAFDTKLRTSMAENEIKGLGIDADVISFNGLLVKFAKEQNASVIIRGLRAVSDFDYEFQMSWVNYKLLPEIETIFLPASEDTQFISSSFVKEIARLGEDVSKFVSKGVQNELINLNRIKNGE
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPDS_CLOD6
Sequence: MRKHSDCMNFCAVDATKGICRLSKQMINLDDAACPEIKVMPKCKNCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE
What is the function of this protein?
Component of the HPA decarboxylase that decarboxylates phenylacetates with a hydroxyl group in the p-position.  Active toward 4-hydroxyphenylacetate and 3,4-dihydroxyphenylacetate, forming 4-methylphenol and 4-methylcatechol, respectively.  Is likely involved in the catabolism of aromatic amino acids such as tyrosine fermentation.  4-methylphenol (p-cresol) formation provides metabolic toxicity, which allows an active suppression of other microbes and may provide growth advantages for the producers in highly competitive environments (By similarity).  The small subunit is essential for enzymatic activity of HPA decarboxylase, and seems also involved in the regulation of the enzyme oligomeric state and catalytic activity (By similarity).
What are the official names of this protein?
4-hydroxyphenylacetate decarboxylase small subunit, HPA decarboxylase small subunit, 4-hydroxyphenylacetate decarboxylase gamma subunit, p-hydroxyphenylacetate decarboxylase small subunit.
What is the protein family that this protein belongs to?
Belongs to the HPA decarboxylase small subunit family.
Protein: SPA_STAAN
Sequence: MKKKNIYSIRKLGVGIASVTLGTLLISGGVTPAANAAQHDEAQQNAFYQVLNMPNLNADQRNGFIQSLKDDPSQSANVLGEAQKLNDSQAPKADAQQNNFNKDQQSAFYEILNMPNLNEAQRNGFIQSLKDDPSQSTNVLGEAKKLNESQAPKADNNFNKEQQNAFYEILNMPNLNEEQRNGFIQSLKDDPSQSANLLSEAKKLNESQAPKADNKFNKEQQNAFYEILHLPNLNEEQRNGFIQSLKDDPSVSKEILAEAKKLNDAQAPKEEDNKKPGKEDGNKPGKEDGNKPGKEDNKKPGKEDGNKPGKEDNNKPGKEDGNKPGKEDNNKPGKEDGNKPGKEDGNKPGKEDGNGVHVVKPGDTVNDIAKANGTTADKIAADNKLADKNMIKPGQELVVDKKQPANHADANKAQALPETGEENPFIGTTVFGGLSLALGAALLAGRRREL
What is the function of this protein?
Plays a role in the inhibition of the host innate and adaptive immune responses.  Possesses five immunoglobulin-binding domains that capture both the fragment crystallizable region (Fc region) and the Fab region (part of Ig that identifies antigen) of immunoglobulins (By similarity).  In turn, Staphylococcus aureus is protected from phagocytic killing via inhibition of Ig Fc region.  In addition, the host elicited B-cell response is prevented due to a decrease of antibody-secreting cell proliferation that enter the bone marrow, thereby decreasing long-term antibody production.  Inhibits osteogenesis by preventing osteoblast proliferation and expression of alkaline phosphatase, type I collagen, osteopontin and osteocalcin.  Acts directly as a pro-inflammatory factor in the lung through its ability to bind and activate tumor necrosis factor alpha receptor 1/TNFRSF1A (By similarity).
What are the official names of this protein?
Immunoglobulin G-binding protein A, IgG-binding protein A, Staphylococcal protein A, SpA.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin-binding protein SpA family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Newly synthesized protein is deposited at 2-4 foci/cell and eventually is distributed in a ring around the cell (PubMed:17416657). Anchored to the cell wall by sortase A (By similarity).
Protein: CAPSD_BPJP3
Sequence: MATLRSFVLVDNGGTGDVTVVPVSNANGVAEWLSNNSRSQAYRVTASYRASGADKRKYTIKLEVPKIVTQVVNGVELPVSAWKAYASIDLTIPIFAATDDVTVISKSLAGLFKVGNPIADAISSQSGFYA
What is the function of this protein?
Acts as a translational repressor of viral replicase synthesis late in infection.  This latter function is the result of capsid protein interaction with an RNA hairpin which contains the replicase ribosome-binding site.
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What are the subcellular locations of this protein?
Virion. Note=The shell is composed of 178 copies of the capsid protein and 1 copy of the maturation protein.
Protein: EFG_BART1
Sequence: MAREYKIEDYRNFGIMAHIDAGKTTMTERILFYTGKNHKIGETHDGASTMDWMEQEQERGITITSAATTTFWEGRDGRKRRFNIIDTPGHVDFTIEVERSLRVLDGAIALLDANAGVEPQTETVWRQAEKYRVPRMVFVNKMDKIGADFYRSVEMVGSRLGAKALVVQLPIGAENDFEGVVDLVEMKALKWDGSIGAPAVIGEIPSDLKEKAEEYREKLIEMAVEVDEAAMEAYLEGVMPTNEQLVSLIRKGTVEVQFHPVLCGTAFKNKGVQPLLDAVVSYLPSPIDIPAIKGIDVKTEAETTRESSDDAPLSMLAFKIMNDPFVGSLTFCRIYSGKVHKGVSLENTVKKKKERLGRMLQMHSNSREDIEEAFAGDIVALAGLKETTTGDTLCDPLKPVILERMEFPEPVIEIAIEPKTKADQEKMGIALNRLAAEDPSFRVKSDEESGQTIIAGMGELHLDIIVDRMRREFKVEANVGQPQVAYRESITKTAEIDYTHKKQSGGAGQFARVKIVFEPHEGDDFIFESKIVGGAVPKEYIPGVQKGIESVMGSGPLAGFPMLGVKATLIDGGYHDVDSSVLAFEIAARAAFRDGAKKAGAQLLEPIMKVEVVTPDDYVGDVIGDLNSRRGQISGTEARGIATVVNAMVPLANMFGYVNTLRSMSQGRAQYTMQFDHYEPVPSAVALEIQKKYA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX3_SALSA
Sequence: MAHQAHAYHMVDPSPWPLTGAIAALLLTSGTAVWFHFHSLTLLTMGNILLLLTMYQWWRDIIREGTFQGHHTPPVQKGLRYGMILFITSEVFFFLGFFWAFYHSSLSPTPELGGCWPPTGIITLDPFEVPLLNTAVLLASGVTVTWAHHSIMEGERKQTIQALTLTILLGFYFTFLQGMEYYEAPFTIADGVYGSTFFVATGFHGLHVIIGSTFLAICLLRQIQYHFTSEHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CH10_ALCBS
Sequence: MSIRPLHDRVLVRREEEETKSAGGIVLPGSAAEKPSRGEVIAVGNGKITENGDVRPLDVKAGDTVIFGQYSGSTVKVEGEELLIMSEAEILAVVED
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMHA_SHESH
Sequence: MLERIKDSFTHSIQTKIDASEALPESIAKAAEMMVHCLLGGNKILACGNGGSAGDAQHFSAELLNRFEVERPPLPAIALTTDTSTITAIANDYSYDEIFSKQILALGQPGDILLAISTSGHSGNVIKAIEAALSRDMTIVALTGKDGGPMAGLLSINDVEIRVPSNSTARIQEVHLLAIHCLCDNIDRTLFPQDEQQ
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPD_PECAS
Sequence: MHQQLQNIIETAFERRADITPANADTVTREAVNQAINLLDSGALRVAEKIDGQWVTHQWLKKAVLLSFRINDNQLIEGGETRFFDKVPMKFADYDEARFQREGVRVAPPASVRRGAYIARNTVLMPSYVNIGAYVDEGTMVDTWVTVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVVVEEGSVISMGVFISQSTRIYDRETGEIHYGRVPAGSVVVSGNLPSKDGSHSMYCAIIVKKVDAKTRGKVGINELLRSID
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBN_THEVB
Sequence: MEPATVLSIALAAVCIGVTGYSIYLSFGPPSKELADPFDDHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: ATPA_HELPH
Sequence: MSQLKLEEISSVIEEKIKNFELDCDMAEVGKVVSYADGVAKVYGLNGVMSYEVLEFETGDKGVAANLEEDSVGVIVFGFGNNIKEGTSVKRTKNLMKVPVGDAVVGRVLNALGEPIDGKGEIETNEFSLIEQKAPGIMDRKSVHEPLQTGIKAIDALVPIGRGQRELIIGDKQTGKTTVAIDAIINQKGQNVICIYVAIGQKESTVAQVVRKLEEYGAMEYSVVINASASDSAAMQYLAPYSGVAMGEYFRDHARHALIVYDDLSKHAVAYREISLILRRPPGREAFPGDVFYIHSRLLERAAKLCDEKGAGSLTALPIVETQAGDVSAYIPTNIISITDGQIFLETDLFYSGIRPAINVGLSVSRVGGAAQIKATKQVSGTLRLDLAQYRELQAFTQFASDLDEASKKQLERGQRMVEVLKQAPYSPLPIEKQVVIIYAGAKGFLDSVSVKKVVDFEEQLHPFLEAKYPQVLEEIHTKKALDKDLEAMLRKVLEEFKLTYSE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MURG_MYCBT
Sequence: MKDTVSQPAGGRGATAPRPADAASPSCGSSPSADSLSVVLAGGGTAGHVEPAMAVADALVALDPRVRITALGTPRGLETRLVPQRGYHLELITAVPMPRKPGGDLARLPSRVWRAVREARDVLDDVDADVVVGFGGYVALPAYLAARGLPLPPRRRRRIPVVIHEANARAGLANRVGAHTADRVLSAVPDSGLRRAEVVGVPVRASIAALDRAVLRAEARAHFGFPDDARVLLVFGGSQGAVSLNRAVSGAAADLAAAGVCVLHAHGPQNVLELRRRAQGDPPYVAVPYLDRMELAYAAADLVICRAGAMTVAEVSAVGLPAIYVPLPIGNGEQRLNALPVVNAGGGMVVADAALTPELVARQVAGLLTDPARLAAMTAAAARVGHRDAAGQVARAALAVATGAGARTTT
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CSRA_SHEHH
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQSEKSGTPSEGGNF
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQO14_PARDE
Sequence: MTSLDFSTILPEVVLAGYALAALMAGAYLGKDRLARTLLWVTVAAFLVVAAMVGLGNHVDGAAFHGMFIDDGFSRFAKVVTLVAAAGVLAMSADYMQRRNMLRFEFPIIVALAVLGMMFMVSAGDLLTLYMGLELQSLALYVVAAMRRDSVRSSEAGLKYFVLGSLSSGLLLYGASLVYGFAGTTGFEGIISTIEAGHLSLGVLFGLVFMLVGLSFKVSAVPFHMWTPDVYEGSPTPVTAFFATAPKVAAMALIARLVFDAFGHVIGDWSQIVAALAVMSMFLGSIAGIGQTNIKRLMAYSSIAHMGFALVGLAAGTAIGVQNMLLYMTIYAVMNIGTFAFILSMERDGVPVTDLAALNRFAWTDPVKALAMLVLMFSLAGVPPTLGFFAKFGVLTAAVDAGMGWLAVLGVIASVIGAFYYLRIVYYMYFGGESEGMTSRMGAVQYLALMVPALAMLVGAISMFGVDSAAGRAAETLVGPVAAIEQPAEAAQAEPVQGE
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit 14, NADH dehydrogenase I subunit 14, NDH-1 subunit 14.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YCGR_LEPCP
Sequence: MSTQPMPLSLTDAKPGQGEYRVRAGSEIRALLRRFADEELPITLATPDGVSYTTCLWADDPERAVLVLSADAADARVQRLIEAEEAVAVGYLDSVKIQFDLNGLMLVHGRDASALHAQFPREIYRFQRRDGFRVRPVGHACPELQLRVSGPTDTELTLRVLDLSHGGLALFLPDDQPALPVGTSVRAARLALDPLTQVQVALRVVHVAPLKESAHGSRLGCEIEGLSGVASRTLQRYIDQTQKRRRLLAVS
What is the function of this protein?
Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner.  Binds 1 c-di-GMP dimer per subunit.  Increasing levels of c-di-GMP lead to decreased motility.
What are the official names of this protein?
Flagellar brake protein YcgR, Cyclic di-GMP binding protein YcgR.
What is the protein family that this protein belongs to?
Belongs to the YcgR family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.