PharMolix/UniProtQA huggingface dataset:
Protein: ENO_BACTN
Sequence: MKIEKIVAREILDSRGNPTVEVDVVLESGIMGRASVPSGASTGEHEALELRDGDKQRYGGKGVQKAVDNVNKIIAPKLIGMSSLNQRGIDYAMLALDGTKTKSNLGANAILGVSLAVAKAAASYLDLPLYRYIGGTNTYVMPVPMMNIINGGSHSDAPIAFQEFMIRPVGAPSFREGLRMGAEVFHALKKVLKDRGLSTAVGDEGGFAPNLEGTEDALNSIIAAIKAAGYEPGKDVMIGMDCASSEFYHDGIYDYTKFEGAKGKKRTAEEQIDYLEELINKFPIDSIEDGMSENDWEGWKKLTERIGDRCQLVGDDLFVTNVDFLAMGIEKGCANSILIKVNQIGSLTETLNAIEMAHRHGYTTVTSHRSGETEDATIADIAVATNSGQIKTGSLSRSDRMAKYNQLLRIEEELGDLAVYGYKRIK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: CXD2_BOVIN
Sequence: MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGCNQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERRYSTVFLALDRDPPESMGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPSGLRTASRSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECDRYPCIKEVECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKIKLAVRGAQAKRKSVYEIRNKDLPRVSVPNFGRTQSSDSAYV
What is the function of this protein?
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
What are the official names of this protein?
Gap junction delta-2 protein, Connexin-36, Cx36, Gap junction alpha-9 protein.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Delta-type subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: ARPC2_BOVIN
Sequence: MILLEVNNRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSISLKFYKELQAHGADELLKRVYGSYLVNPESGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNTINLIHTFRDYLHYHIKCSKAYIHTRMRAKTSDFLKVLNRARPDAEKKEMKTITGKTFSSR
What is the function of this protein?
Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF).  The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility.  Seems to contact the mother actin filament.  In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA.  The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
What are the official names of this protein?
Actin-related protein 2/3 complex subunit 2, Arp2/3 complex 34 kDa subunit, p34-ARC.
What is the protein family that this protein belongs to?
Belongs to the ARPC2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection. Synapse, synaptosome. Nucleus.
Protein: VKT3_ANESU
Sequence: INGDCELPKVVGRCRARFPRYYYNLSSRRCEKFIYGGCGGNANNFHTLEECEKVCGVRS
What is the function of this protein?
Dual-function toxin that inhibits both the serine protease trypsin (Kd<30 nM) and voltage-gated potassium channels Kv1. 2/KCNA2 (IC(50)=1300 nM).
What are the official names of this protein?
KappaPI-actitoxin-Avd3d, KappaPI-AITX-Avd3d, Kalicludine-3, AsKC3.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. Sea anemone type 2 potassium channel toxin subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: RS14_CELJU
Sequence: MAKKSMIAREVKRAETAKKFAAKRAELKAIIASASSSEEQIWEAQTKLQQLPRDASPSRQRNRCRVTGRPHGVYRKFGLCRHKLREAAMRGDVPGLVKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: SIGA3_SYNE7
Sequence: MAKTETPTSDLVRTYLREIGRVPLLTHEEEVVLGKRVQQWMKLQELRQTLQSEEGDRDPSDLEWAAAAGLSIEELRQQQHLGEQAKRKMIEANLRLVVSVAKKYLKRNMDLLDLIQEGTIGMQRGVEKFDPTKGYRFSTYAYWWIRQAITRAIAEKARTIRLPIHITEKLNKIKKMQRQLSQQLGRTATLPELAAALDLTPAQVRDYLEKARHPLSLDLRVGDNQDTELGDLLETDCTTPEEFTLQASMRRDIDRLLDQLTEQQRQVIALRYGLEDGQVMTLASIGDRLQISRERVRQLEREALHTLRQARSQVQEYLAS
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
What are the official names of this protein?
RNA polymerase sigma factor SigA3.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_EXISA
Sequence: MGIIRELPEQLANRIAAGEVVERPASVVKELVENAIDAGATKVDVDLQEAGIRLIKVRDNGHGFHEEDAARAFLRHATSKIRDEHDLFRIRTLGFRGEALASIASVSHVLLKSKRADEDGFEMTLEGGVVKETNPTATNVGTEIAVSQLFFNTPARLKYLKTSATELASITDTLNRLALSHPEIRFTVFHEEKELLRTNGNGDLKQVMLAIYGRQVAAQIVTASSKTSDYTLSAHLVRPEVTRSNKQYVTLILNGRSIKNFALTQSVLEGYHTLLPIGRYPIAVLEVKMDPMLIDVNVHPTKREVRLSKEKELCQLIRETVQLTLREQRLIPSVKQEPKLKRVTPSEQSKLDFSMEPQPKQADSVEWNYPIPRERKETLTSPSQWNPAPLVHEPEAEMIEPEQVEESVRQSERLPALDVIGQLHSSYIICGAEDGMYVMDQHAAQERIKYELFYEQLGRPEKEYQLLLIPLTLEFTQEETLAIEEVLPLLAEAGITLEPFGGNTFLVREIPTWYPQHDLEGTIRDLVEMAIQQRSIDIAKYREEASILMACKRSIKANHPLNMEMMRQLIDDLSRTTSPFTCPHGRPILVKWSTYELEKLFKRVM
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: RRF_STAES
Sequence: MSDIIKDTKSRMQKSIDNLSRELANISAGRANSNLLNGVTVDYYGAPTPVQQLASINVPEARLLVISPYDKSSVADIEKAIIAANLGVNPTSDGEVIRISVPALTEERRKELVKEVKKIGEDAKVSIRNIRRDINDQLKKDEKNGDITEDDLRSQTDDVQKATDNSIKEIDQLVADKEKDIMSV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_MARMS
Sequence: MKFVDEASIYVRAGKGGNGALSFWREKFVAKGGPDGGDGGNGGSVVLVADEALNTLIDFRFTKKYIAESGEGGQGRDMTGSKGADLEIKVPVGTTVIDEDTGETLGDLVRDGQKLKVAQGGHHGLGNTRFKSSTNRAPRQTTKGTVGEERTLKLEMKVLADVGLLGLPNAGKSTFIRAVSSAKPKVADYPFTTLVPNLGVVKVKKHQSFVIADIPGIIEGASEGAGLGIRFLKHLVRNRILLHIVDLAPWDEITPAEAAVIAVNELHQFSPALAERERWLVLNKTDMVPEDELEERCQSVIDALGWEGKAYRISAISGEGTEVLCLDLMTALDEKRELLLESPEAREKEKAVRALIDEEGRNRIMSLREKRRKAGLLLDDDDFDEDDYDVEVEYVS
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK20_CHAVU
Sequence: MTRVKRGYVARKRRRSILCQRAGSRGAHSILFRNAQQQNMKAMIYSHEHRKKRKRDFRSLWVTRINAAVREQGLSYNKFIFLLKTHKVLLNRKMLAQIAILDITSFKKLLLVIN
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KCY_PSEA7
Sequence: MNAAVPMLAIDGPSGAGKGTVAGLLARRLGWNLLDSGALYRLLAFAAVNHGVDLTNEEALKLLAAHLDVQFVAADDSHGQRIILEGEEVTDVIRTEQVGAGASQVAALPAVRDALLQRQRAFREAPGLVADGRDMGTVVFPDAPLKIFLTASAEERARRRYLQLKAKGADVDQSALLEEIRERDERDSQRAVAPLKPADDAILLDSTEMSIEAVVETIIHHCEQQGWDV
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFC2B_ORYSJ
Sequence: MAAAAGGGAAPFVWKTYRMVEDPGTDGVIGWGKGNNSFVVADPFVFSQTLLPAHFKHNNFSSFVRQLNTYGFRKVDPDRWEFAHASFLRGQTHLLRNIVRRGSAAAGGGGGGGGGKRRDASADGGGGGGDEDMTMVATEVVRLKQEQRTIDDRVAAMWRRVQETERRPKQMLAFLLKVVGDRDKLHRLVGGGGNGNGAATAAAADNGFADAARAGCGEKRARLLLDGDNTGAFGPDAVDFAGFYTGADMFPDVAVDAAAAAAGGSAGCSFAFGVDSGY
What is the function of this protein?
Transcriptional regulator that specifically binds DNA of heat shock promoter elements (HSE).
What are the official names of this protein?
Heat stress transcription factor C-2b, Heat stress transcription factor 16, OsHsf-16.
What is the protein family that this protein belongs to?
Belongs to the HSF family. Class C subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: YP247_YEAST
Sequence: MDPFHNGNKRSSISFGSSQRQPYNKNNYLSGTNGPSSAAQDQGRGPSPFGMSGNTTNGGNSKRNSGCDLSATYYASRSPMYSPLDFSPPVFSPNHSQLQQARGYAANIPVVSNLMNPSMASVCEYQSHYPLFGLDWSADDYVCLGSYKEDSRNKLQVLHSNDLLSWESVVDADVVYPVSKIQWVPSQLYPRKLATCSDSLRIWSVSPEERQFQEQINLSLCKYNRQHPANPAAADDMKVIGTFPPITSFDWNTVDTNLIISSSIDTTCIVWDLQSSHYVKTQLIAHDSEVFDVRFLTKSTQLFASCGGDGSVRVFDLRSLAHSTIIYEPPSSSVSGATAGTITPSSKGSDALLRLEPSPYDPNVLATFAADSNKIIILDMRNPESPILNLQGHGSSVNGIKWHPTKRNVLLSCGDDCQVLYWDLNSSFMEINAAGSKSPSIHGTSLEDPDGDTEMTDGGAGSGLNEDPLSLNNNSKQVCKTLETPNMMYANKTQEINNIAWRPQRGDWFGCVSGKKFQNVRVL
What are the official names of this protein?
WD repeat-containing protein YPL247C.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR68 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL2_CLOPE
Sequence: MALKKFNPTTPSRRQMTMPTFEEVTTNAPEKSLLVSLKKTGGRNAQGKITVRHHGGGAKRKYRIIDFKRNKDGIPAKVATVEYDPNRSAYIALVVYADGEKRYILAPVGLKVGDTVVSGPEADIKPGNALQLKHMPVGTFVHNIELQAGKGGQMVRSAGTSAQLMAKEGNYATLRLPSGEMRYVRIECKATVGTVSNTTHEIVNIGKAGRKRHMGWRPTVRGSVMNPCDHPHGGGEGRSPIGRPSPVTPWGKPALGYKTRKNKKYSDRFIIKRRNAK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RS4_LACAC
Sequence: MSRYTGPSWKRSRRLGISLSGTGKELARRNYAPGQHGPNSRGRLSEYGQQLHEKQKLRWMYGLNERQFRTLFIRAGKIREGQHGINFMILLERRLDSIVYRLGLATTREQARQLVNHGHITVDGKRVDIPSYEVSVGQTIGLKDKSKNLQQIRDALEATTARPSFVSFDENKMEGTLVRLPERDEMEPEIDESLVVEWYNKLL
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: T55BB_DANRE
Sequence: MADGERSPLLLDGRDGMTGLSLGDEPYRPISKPQNFAVFPSAPPMLGEAPPPYSPLGSPESSSAPVISCRVCQSLISVEGKIHQHVVKCGVCNEATPIKNAPAGKKYVRCPCNCLLICKVTSQRIACPRPYCKRVINLGPVNPGAGSPNPQPTGARVSCGHCAKTFLWTEFTDRTLARCPHCRKVSSIGQRYPRKRSLICFLLCLIFVITTAGLIAGTWLKAQKYKGIYASWVFFIVLVLVTLVRALHWACMKISEPLHNYS
What is the function of this protein?
Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 4,5-bisphosphate.
What are the official names of this protein?
Type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase-B, PtdIns-4,5-P2 4-Ptase I-B, Transmembrane protein 55B-B.
What are the subcellular locations of this protein?
Late endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi- pass membrane protein.
Protein: RBFA_CLONN
Sequence: MARYRLGRINEEVKKEISNIIRDDIHDPRLTGMVSVTRVEVTNDLRYAKVFISIFGSDESKTETLEALKSSAGFIRREVGHRVKLRYTPEILLELDESIEHGMHINDLLSNLKEKKRNDNR
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECTD_BORPA
Sequence: MISPAQDPYASRTDRSSAIIARQDPVVYGEGKFADALSADQVQSYERDGFLLLENLFSDEEVAALLAEVERMTRDPAIVRREEAITEPGSNAVRSIFMVHVLSPILGRLVRDPRLANAARQILGAEVYVHQSRANMKPGFKGKEFYWHSDFETWHVEDGMPSMRALSCSVLLTDNNEANGPLMLVPGSHRQFISCVGETPRDHYKQSLKKQEYGVPDPVSLQLLAEQGGISTMTGKAGSVVFFDCNTMHGSNSNISPWPRANVFMVYNSMENTLNPPKYGLNPRPEHIATRQAFKAVRPLDSLKLVER
What is the function of this protein?
Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte.  Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.
What are the official names of this protein?
Ectoine dioxygenase, Ectoine hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the PhyH family. EctD subfamily.
Protein: YCIB_BURTA
Sequence: MKFLFDLFPIILFFAAFKLWGIFTATAVAIAATLAQVAWVAFRHRKVDTMLWVSLGVIVVFGGATLVLHDEKFIQWKPTVLYWLFAVGLVAARYAFGKNLIEKMMGKQLTLPEPVWDKLNLAWAAFFAALGVTNLYVVRNFTESQWVNFKLFGTTGAIIVFVILQSLWLAKYLKGE
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS15_MYCTU
Sequence: MALTAEQKKEILRSYGLHETDTGSPEAQIALLTKRIADLTEHLKVHKHDHHSRRGLLLLVGRRRRLIKYISQIDVERYRSLIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: PP2B2_ARATH
Sequence: MIQSTMGHKQSVDSRGKGRKVPGSSSMVQKHRVESSGGAIISGPSLFDNLPEDCISNIISFTSPRDACVAASVSKTFESAVNSDSVWDKFLPSDYSSLVPPSRVFSSKKELYFAICDNPVLVEDGGKSFWLEKENGKKCFMLSPKKSMWITWVSTPQYWRWISIPEARFEEVPELLNVCWFEVRGGMNTKELSPGTRYSAYIVFKTKNGCPNLGDVPVEATVGLVGQESSQRHIYFVGPSDQRRDRETRDVTRPTKRKDGWMEAELGQFFNESGCDVVDTSILEIKTPYWKRGLIIQGIEFRPTKSLFYI
What are the official names of this protein?
Putative F-box protein PP2-B2, Protein PHLOEM PROTEIN 2-LIKE B2, AtPP2-B2.
Protein: Y1102_ARCFU
Sequence: MDEKAKAMLMLGVLNDAFGDIRNMIYYLQDFIYSHPDWAEDFEKLGLNDVLNAARELEKLTLEKMDLLKRIAEGKE
What are the official names of this protein?
Uncharacterized protein AF_1102.
Protein: XYLA_THEP1
Sequence: MMEFFPEIPKIQFEGKESTNPLAFKFYDPNEVIDGKPLKDHLKFSVAFWHTFVNEGRDPFGDPTAERPWNRFSDPMDKAFARVDALFEFCEKLNIEYFCFHDRDIAPEGKTLRETNKILDKVVERIKERMKDSNVKLLWGTANLFSHPRYMHGAATTCSADVFAYAAAQVKKALEITKELGGEGYVFWGGREGYETLLNTDLGLELENLARFLRMAVEYAKKIGFTGQFLIEPKPKEPTKHQYDFDVATAYAFLKNHGLDEYFKFNIEANHATLAGHTFQHELRMARILGKLGSIDANQGDLLLGWDTDQFPTNIYDTTLAMYEVIKAGGFTKGGLNFDAKVRRASYKVEDLFIGHIVGMDTFALGFKIAYKLVKDEVLDRFIEEKYRSFKEGIGKEIVEGKADFEKLEEYIIDKEDIELPSGKQEYLESLLNSYIVKTIAELR
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSCL_LARHH
Sequence: MFKEFREFAMRGNVIDLAVGVVIGAAFGSIVKSLVDDIIMPPIGLLIGKVNFADLFITLKAGATPGPYATVAAAKAAGAVTMNVGQFINSVVSFVLIAFSVFLLVKVVNRLYQKKDAAAPAPATRDCPFCATAIPLAATRCPHCTSQVPPAD
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SUI1_METM5
Sequence: MPEICPICGLPKDLCVCEEIAKEEQKIKVYVTKRRFGKLMTVVDGFDADLIDVKDLAKKLKDICACGGTVKKDSIELQGDHRRKAEETLIKMGFSKDMIDVR
What are the official names of this protein?
Protein translation factor SUI1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SUI1 family.
Protein: COQ4_XENLA
Sequence: MKILLSCLRFSPVWRGPRSAACVMQGGKLQRFQSYNTAEEGIEEDIQFAATNQESSSLLYPDHIPTNAVQKLLLSAGSAVMALYDPYRHDMVAVLGETTGAVALRKLRDQMRRDPEGLQILQERPRISTSTLDMQALREMQDGTLGREYARFLDVNRVTPDTRMPVKFVDDEELAYVAQRYREVHDLMHTLLGMPTNMLGEVVVKWFEAVQTGLPMCILGAAFGPLRLNNKRMQKLGVLVPWAVQSGRNARCVLNFHYENRWEQSVLSLRKEIGILPLPEIKA
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial, Coenzyme Q biosynthesis protein 4 homolog.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: UBP33_PONAB
Sequence: MSAFRNHCPHLDSVGEITKEDLIQKSQGTCQDCKVRGPNLWACLENRCSYVGCGESQVDHSTIHSQETKHYLTVNLTTLRVWCYACSKEVFLDRKLGTQPSLPHVRQPHQIQENSVQDFKIPSNTTLKTPLVAVFDDLDIEVDEEDELRARGLTGLKNIGNTCYMNAALQALSNCPPLTQFFLDCGGLARTDKKPAICKSYLKLMTELWHKSRPGSVVPTNLFQGIKTVNPTFRGYSQQDAQEFLRCLMDLLHEELKEQVMEVEDPQTITTEETMEEDKSQSDVDFQSCESCSNSDKAENENGSSCFSEDNNETTMLIQDDENNSEMSKDWQKEKMCNKINKVNSEGELDKDRDSISETVDLNNQETVKVQIHSRASEYITDVHSNDLSTPQILPSNESINPRLSASPPKSGNLWPGLAPPHKKAQSASPKRKKQHKKYRSVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKEDLAKLHSSSHPTSIVKAGSCGEAYAPQGWIAFFMEYVKRFVVSCVPSWFWGPVVTLQDCLAAFFARDELKGDNMYSCEKCKKLRNGVKFCKVQKFPEILCIHLKRFRHELMFSTKISTHVSFPLEGLDLQPFLAKDSPAQIVTYDLLSVICHHGTASSGHYIAYCRNNLNNLWYEFDDQSVTEVSESTVQNAEAYVLFYRKSSEEAQKERRRISNLLNIMEPSLLQFYISRQWLNKFKTFAEPGPISNNDFLCIHGGVPPRKAGYIEDLVLMLPQNIWDNLYSRYGGGPAVNHLYICHTCQIEAEEIEKKKKNRRKTELEIFIRLNRAFQKEDSPATFYCISMQWFREWESFVKGKDGDPPGPIDNTKIAVTKCGSVMLRQGADSGQISEETWNFLQSIYGGGPEVILRPPVVHVDPDILQAEEKIEVETRSL
What is the function of this protein?
Deubiquitinating enzyme involved in various processes such as centrosome duplication, cellular migration and beta-2 adrenergic receptor/ADRB2 recycling.  Involved in regulation of centrosome duplication by mediating deubiquitination of CCP110 in S and G2/M phase, leading to stabilize CCP110 during the period which centrioles duplicate and elongate.  Involved in cell migration via its interaction with intracellular domain of ROBO1, leading to regulate the Slit signaling.  Plays a role in commissural axon guidance cross the ventral midline of the neural tube in a Slit-dependent manner, possibly by mediating the deubiquitination of ROBO1.  Acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination of beta-arrestins (ARRB1 and ARRB2) and beta-2 adrenergic receptor (ADRB2).  Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2.  Upon dissociation, it is probably transferred to the translocated beta-arrestins, leading to beta-arrestins deubiquitination and disengagement from ADRB2.  This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins.  Deubiquitinates DIO2, thereby regulating thyroid hormone regulation.  Mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 33, Deubiquitinating enzyme 33, Ubiquitin thioesterase 33, Ubiquitin-specific-processing protease 33.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP20/USP33 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Associates with centrosomes predominantly in S and G2 phases but less in G1 phase (By similarity).
Protein: GCH4_PSET1
Sequence: MPDIANTAPALQTGTLDWVGMGEIELPFIFESHGITPVTVNAKARAFVNLHKEDAKGIHMSRLFLALDTLSTEQQVNPQTLAQALDFFISSHEGLSDKALIEFKFELPLRRKSLLSDKAGWKSYPVILTSTIEQGVINYELSVDVTYSSTCPCSAALARQLIQNAFAEKFSQETLSQKEALEWLGTTQGIVATPHSQRSIANVKVKLDSNITQFDVVNLINTIEDELKTPVQAAVKREDEQEFARLNGQNLMFCEDAARKIKALLETQQYSDYWLQINHYESLHAHDALAIAVKGVAGGYRA
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: RUVA_RHOPA
Sequence: MIGKLKGIIDSYGEDYVILDVQGVGYQVHCASRTLQALPSPGEAATLSIETYVREDQIKLFGFRTDTEREWFRLLQTVQSVGAKVALAVLSTLPPHDLANAIALRDKAAVARTPGVGPKVAERIVTELKDKVPALSAVDPAVVKLSGAIDDNRAPRAVADAISALVNLGYGQPQAAAAVATASRTAGEDAETAQLIKLGLKELSK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: DEF1_COREF
Sequence: MTVRDVRIFGDPVLTSRADEVVDFDESLATLIDDMFDTMEDAGGVGLAANQVGVLRRVFVFDCSHVDGGLRGHVVNPVWEPIGEETQTGKEGCLSIPDVSAETTRYETVKLSGQDRDGNPIGLVASGLLSRCIQHETDHLDGVLFLKRLDPAERKAAMGVIRASDWFNK
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase 1, PDF 1, Polypeptide deformylase 1.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.