PharMolix/UniProtQA huggingface dataset:
Protein: FHP_YEAST
Sequence: MLAEKTRSIIKATVPVLEQQGTVITRTFYKNMLTEHTELLNIFNRTNQKVGAQPNALATTVLAAAKNIDDLSVLMDHVKQIGHKHRALQIKPEHYPIVGEYLLKAIKEVLGDAATPEIINAWGEAYQAIADIFITVEKKMYEEALWPGWKPFDITAKEYVASDIVEFTVKPKFGSGIELESLPITPGQYITVNTHPIRQENQYDALRHYSLCSASTKNGLRFAVKMEAARENFPAGLVSEYLHKDAKVGDEIKLSAPAGDFAINKELIHQNEVPLVLLSSGVGVTPLLAMLEEQVKCNPNRPIYWIQSSYDEKTQAFKKHVDELLAECANVDKIIVHTDTEPLINAAFLKEKSPAHADVYTCGSLAFMQAMIGHLKELEHRDDMIHYEPFGPKMSTVQV
What is the function of this protein?
In the presence of oxygen and NADH, it has NADH oxidase activity, which leads to the generation of superoxide and H(2)O(2).  Under anaerobic conditions, it also exhibits nitric oxide reductase and FAD reductase activities.  However, all these reactions are much lower than NOD activity.
What are the official names of this protein?
Flavohemoprotein, Flavohemoglobin, Hemoglobin-like protein, Nitric oxide dioxygenase, NO oxygenase, NOD.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRC_LEPCP
Sequence: MTTTLTLIRPDDWHLHVRDGAALAAVVPHTARQFARAIIMPNLRPPVTTAAQAVAYRERIAAAVPAGVDFTPLMTLYLTDNTPADEIVRAQAAGVVALKLYPAGATTNSDAGVTDVRKTYAALEAMQRAGMPLLVHGEVTDPAVDVFDREAVFIDQVMRPLRRDFPELKVVFEHITTQEAADYVAEADAHTAATITAHHLLYNRNAIFTGGLRPHYYCLPVLKREVHRLALVKAATSGSSKFFLGTDSAPHPAHLKEHAAACAGCYTALSAIELYAQAFDDAGALDKLEGFASLHGPDFYGLPRNSGTLTLRREPWQLPETLAFGDAQLKPLCGGETLDWRLLA
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: RSBW_BACAN
Sequence: MMERFEKIEMKIPAKAEYVAIIRLTMAGVANRMGFAYDDIEDMKIAISEACTNIVQHAYKEDVGEIAIVFGLYENRLEIMVADNGVSFDFNNLRSKVGPYDISKPVEHLPENGLGLYLINTLMDDIQIMHDEGMTVLMTKYIQREQVENDGNPISTYESY
What is the function of this protein?
Negative regulator of sigma-B activity.  Phosphorylates and inactivates its specific antagonist protein, RsbV.  Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
What are the official names of this protein?
Serine-protein kinase RsbW, Anti-sigma-B factor, Sigma-B negative effector RsbW.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: PLCD2_ARATH
Sequence: MSKQTYKVCFCFRRRFRYTASEAPREIKTIFEKYSENGVMTVDHLHRFLIDVQKQDKATREDAQSIINSASSLLHRNGLHLDAFFKYLFGDNNPPLALHKVHHDMDAPISHYFIFTGHNSYLTGNQLSSDCSEVPIIDALKKGVRVIELDIWPNSNKDDIDVLHGMTLTTPVGLIKCLKAIRAHAFDVSDYPVVVTLEDHLTPDLQSKVAEMVTEIFGEILFTPPVGESLKEFPSPNSLKRRIIISTKPPKEYKEGKDVEVVQKGKDLGDEEVWGREVPSFIQRNKSEAKDDLDGNDDDDDDDDEDKSKINAPPQYKHLIAIHAGKPKGGITECLKVDPDKVRRLSLSEEQLEKAAEKYAKQIVRFTQHNLLRIYPKGTRVTSSNYNPLVGWSHGAQMVAFNMQGYGRSLWLMQGMFRANGGCGYIKKPDLLLKSGSDSDIFDPKATLPVKTTLRVTVYMGEGWYFDFRHTHFDQYSPPDFYTRVGIAGVPGDTVMKKTKTLEDNWIPAWDEVFEFPLTVPELALLRLEVHEYDMSEKDDFGGQTCLPVWELSEGIRAFPLHSRKGEKYKSVKLLVKVEFV
What is the function of this protein?
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.  At physiological calcium concentration, the preferred substrate is phosphatidylinositol 4,5-bisphosphate versus phosphatidylinositol.
What are the official names of this protein?
Phosphoinositide phospholipase C 2, Phosphoinositide phospholipase PLC2, AtPLC2, PI-PLC2.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: M235_CONVE
Sequence: MLKMGVVLFIFLVLFTLATLQLDADQPVERYAENKRLMSPYKRRAILHAPREQECCEPQWCDGGCDACC
What are the official names of this protein?
Conotoxin VnMLKM-04.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BBX25_ARATH
Sequence: MKIQCDVCEKAPATLICCADEAALCAKCDVEVHAANKLASKHQRLFLDSLSTKFPPCDICLEKAAFIFCVEDRALLCRDCDEATHAPNTRSANHQRFLATGIRVALSSTSCNQEVEKNHFDPSNQQSLSKPPTQQPAAPSPLWATDEFFSYSDLDCSNKEKEQLDLGELDWLAEMGLFGDQPDQEALPVAEVPELSFSHLAHAHSYNRPMKSNVPNKKQRLEYRYDDEEEHFLVPDLG
What is the function of this protein?
Acts as negative regulator of seedling photomorphogenesis (PubMed:18540109).  BBX25/STH and BBX24/STO function as transcriptional corepressors of HY5 activity, leading to the down-regulation of BBX22 expression.  BBX25/STH acts additively with BBX24/STO during de-etiolation and the hypocotyl shade avoidance response (PubMed:23624715).
What are the official names of this protein?
B-box zinc finger protein 25, Protein SALT TOLERANCE HOMOLOG 1, Salt tolerance-like protein.
Protein: BIOD_AQUAE
Sequence: MRLLITGTDTGVGKTFITYNLAKELKERGYKVGCLKPVETYVREVPEDGSLLSKATGQSVNEIVPVRFSLPLAPYAATLEEGRDFALEELGKHYEELSKKYKFLLVEGAGGIAVPIKKNYTYANLARDWKLKVLIVGRAGLGTINHTFLTWYYAKATGLEVIGIILNGFTGEDVSERTNPQIIEEMTGIKPYKVPRIQDVELPKDIRTGLADYVLSRFTP
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_CROS5
Sequence: MAPNDIISDMLTRIRNACAVRHPTTVVPTTKMTRSIAQVLKEEGFIEGFEEVGEGVKKHLVISLKYKSRGRQPIINTLQRVSKPGLRVYSNRKDLPRVLGGIGIAIISTSKGIMTDREARRQNVGGEVLCYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RL2A_SCHPO
Sequence: MGRVIRAQRKSGGIFQAHTRLRKGAAQLRTLDFAERHGYIRGVVQKIIHDPGRGAPLAKVAFRNPYHYRTDVETFVATEGMYTGQFVYCGKNAALTVGNVLPVGEMPEGTIISNVEEKAGDRGALGRSSGNYVIIVGHDVDTGKTRVKLPSGAKKVVPSSARGVVGIVAGGGRIDKPLLKAGRAFHKYRVKRNCWPRTRGVAMNPVDHPHGGGNHQHVGHSTTVPRQSAPGQKVGLIAARRTGLLRGAAAVEN
What are the official names of this protein?
60S ribosomal protein L2-A, K37, K5, KD4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: PDE2_YEAST
Sequence: MSTLFLIGIHEIEKSQTIVQNEHYFDRVIELQDLDSLMVALYKDRVSPFPNVHNFETGVSIVLYDPSKFQLSVRQLDVLFKRFFPSFNISAIDHTREENLQRLECVERENSICRNRITRINHWMYHHHDDTPDGINKNSYGTVNGNSVPTQACEANIYTLLLHLNDSKAQHLRKASVPRLIRNIEFMSFLSDPIEKISQEGSHYWNILSTWDFCALSLSTQELIWCGFTLIKKLSKDAKVLIADNKLLLLLFTLESSYHQVNKFHNFRHAIDVMQATWRLCTYLLKDNPVQTLLLCMAAIGHDVGHPGTNNQLLCNCESEVAQNFKNVSILENFHRELFQQLLSEHWPQLLSISKKKFDFISEAILATDMALHSQYEDRLMHENPMKQITLISLIIKAADISNVTRTLSISARWAYLITLEFNDCALLETFHKAHRPEQDCFGDSYKNVDSPKEDLESIQNILVNVTDPDDIIKDHPHIPNGQIFFINTFAEVFFNALSQKFSGLKFLSDNVKINKEYWMKHKKPQ
What is the function of this protein?
Controls the level of cAMP in yeast cells, together with the low-affinity cAMP phosphodiesterase (PDE1).
What are the official names of this protein?
3',5'-cyclic-nucleotide phosphodiesterase 2, PDEase 2, High-affinity cAMP phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family.
Protein: RPOB_ORYSA
Sequence: MLRNGNEGMSTIPGFSQIQFEGFCRFINQGLAEELEKFPTIKDPDHEISFQLFAKGYQLLEPSIKERDAVYESLTYSSELYVSARLIFGFDVQKQTISIGNIPIMNSLGTFIINGIYRIVINQILLSPGIYYRSELDHKGISIYTGTIISDWGGRSELAIDKKERIWARVSRKQKISILVLSSAMGSNLKEILDNVSYPEIFLSFPNAKEKKRIESKEKAILEFYQQFACVGGDLVFSESLCEELQKKFFQQKCELGRIGRRNMNRRLNLDIPQNSTFLLPRDVLAATDHLIGMKFETGILDDDDMNHLKNKRIRSVADLLQDQFGLALGRLQHAVQKTIRRVFIRQSKPTPQTLVTPTSTSILLITTYETFFGTYPLSQVFDQTNPLTQTVHGRKVSCLGPGGLTGRTASFRSRDIHPSHYGRICPIDTSEGINVGLTGSLAIHARIDHWWGSVESPFYEISEKAKKKKERQVVYLSPNRDEYYMIAAGNSLSLNRGIQEEQVVPARYRQEFLTIAWEQIHVRSIFPFQYFSIGGSLIPFIEHNDANRALMSSNMQRQAVPLSRSEKCIVGTGLERQTALDSRVSVIAEREGKIISTNSHKILLSSSGKTISIPLVTHRRSNKNTCMHQKPRVPRGKSIKKGQILAEGAATVGGELALGKNVLVAYMPWEGYNFEDAVLISERLVYEDIYTSFHIRKYEIQTDTTSQGSAEKITKEIPHLEEHLLRNLDRNGVVKLGSWVETGDILVGKLTPQIASESSYIAEAGLLRAIFGLEVSTSKETSLKLPIGGRGRVIDVKWIQRDPLDIMVRVYILQKREIKVGDKVAGRHGNKGIISKILPRQDMPYLQDGTPVDMVFNPLGVPSRMNVGQIFESSLGLAGDLLKKHYRIAPFDERYEQEASRKLVFSELYEASKQTKNPWVFEPEYPGKSRIFDGRTGDPFEQPVLIGKSYILKLIHQVDEKIHGRSTGPYSLVTQQPVRGRAKQGGQRIGEMEVWALEGFGVAHILQEILTYKSDHLIARQEILNATIWGKRVPNHEDPPESFRVLVRELRSLALELNHFLVSQKNFQVNREEV
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS14_STRPS
Sequence: MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNASPTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: TRMD_HALOH
Sequence: MNFDILTLFPEMFDGPFNNSIIGKARDRGLIDINLIDIRDYTTDKHNTADDYPYGGGAGMVMKVEPIYRALTDVRSKRKGEYPVVLLSPQGKTLDQNLVKSLSKHDGLILICGHYEGVDERVRQIFSPLEISIGDYVVTGGEIGAIVLVDAVSRMIPGVLGDERSKVEDSFYNGILDYPHYTRPRVYQNLKVPDVLLSGNHGLIEKWRKKQALKRTLIRRPDLLKNKKLTPEEEELLEEAKAEIEGEYND
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNP4_SULAC
Sequence: MKVKNVKPYKRRSLELIEMAIDMTKNREYQLAREYTKLAITYSRKFRFKIPIEYKRSICRKCYVPLVIGLTERRRIKNKVVIRTCLLCGWVRRYELKRDSKEGKGIPPRHKNRQERTQ
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 4, RNase P component 4, Rpp21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GHRA_ECO45
Sequence: MDIIFYHPTFDTQWWIEALRKAIPQARVRAWKSGDNDSADYALVWHPPVEMLAGRDLKAVFALGAGVDSILSKLQAHPEMLKPSVPLFRLEDTGMGEQMQEYAVSQVLHWFRRFDDYRIQQNSSHWQPLPEYHREDFTIGILGAGVLGSKVAQSLQTWRFPLRCWSRTRKSWPGVQSFAGREELSAFLSQCRVLINLLPNTPETVGIINQQLLEKLPDGAYLLNLARGVHVVEDDLLAALDSGKVKGAMLDVFNREPLPPESPLWQHPRVTITPHVAAITRPAEAVEYISRTIAQLEKGERLCGQVDRARGY
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase A, 2-ketoacid reductase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZDHC6_PONAB
Sequence: MGTFCSVIKFENLQELKRLCHWGPIIALGVIAICSTMAMIDSVLWYWPLHTTGGSVNFIMLINWTVMILYNYFNAMFVGPGFVPLGWKPEISQDTMYLQYCKVCQAYKAPRSHHCRKCNRCVMKMDHHCPWINNCCGYQNHASFTLFLLLAPLGCIHAAFIFVMTMYTQLYHRLSFGWNTVKIDMSAARRDPLPIVPFGLAAFATTLFALGLALGTTIAVGMLFFIQMKIILRNKTSIESWIEEKAKDRIQYYQLDEVFVFPYDMGSRWRNFKQVFTWSGVPEGDGLEWPVREGCHQYSLTIEQLKQKADKRVRSVRYKVIEDYSGACCPLNKGIKTFFTSPCTEEPRIQLQKGEFILATRGLRYWLYGDKILDDSFIEGVSRIRGWFPRKCVEKCPCDAETDQAPEGEKKNR
What is the function of this protein?
Endoplasmic reticulum palmitoyl acyltransferase that mediates palmitoylation of proteins such as AMFR, CALX, ITPR1 and TFRC (By similarity).  Palmitoylates calnexin (CALX), which is required for its association with the ribosome-translocon complex and efficient folding of glycosylated proteins (By similarity).  Mediates palmitoylation of AMFR, promoting AMFR distribution to the peripheral endoplasmic reticulum (By similarity).  Together with SELENOK, palmitoylates ITPR1 in immune cells, leading to regulate ITPR1 stability and function (By similarity).  Stearoyltransferase that mediates stearoylation of TFRC to inhibit TFRC-mediated activation of the JNK pathway and mitochondrial fragmentation (By similarity).
What are the official names of this protein?
Palmitoyltransferase ZDHHC6, Stearoyltransferase ZDHHC6, Zinc finger DHHC domain-containing protein 6, DHHC-6.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
Protein: ZNUC_ANAMM
Sequence: MSSNHQHFRQPAIKGGESRVLSRRAILTADSLTLFYEDKKVIDNVSFSVKFGEIVTILGPNGGGKTSLVRVLVGINKAYKGTVRYFGKLGIGYLPQNIKINRLMPMTVEYFLLHTYLGRRAASDLEDSMKYVDVERLLKRQVAELSAGETQLVLLARCLMMKPDLIILDEPVSCMDIEAKHNFYKLVARLVTECGVSVLMTSHDLHCVMSCSDRVICVNHSIRCEGTPEEITENAKFLSVFPNNV
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y783_RICFE
Sequence: MPLSNNQKFYIAETVEEKALCNAVRNSNVNEALSLILKLIEANQFQKFNGDLRDRDPEETYYEVYYPLLSVAVLKRNFKMFEMLLEYGFKPHAISSGLNPETTPLIEASRCGRGDMVLKLTSILNKDELNYYDKDIKNSALYYAIKNNHVNIFNVLTSMTKGVDVDFEVSMEVTIISSNFNLFIHFFYNALQGIQDEVLRKGYLLQCAASKKIYK
What are the official names of this protein?
Putative ankyrin repeat protein RF_0783.
Protein: IALB_BARBK
Sequence: MKKILNLFVISAFLSISSAAFAQNVKPAATKPSVATLPNGASSLTETYGLWSVNCGIQDGNKICIMLRQEVNEQDRVLLSMSVSLDGEGTVSGNLTIPFGILVSKPIRLHVDDSKSVIESNVRTCVPAGCVVPIVFDKNFVGSLRAGKQLKLSMTVAAPGEPTLDNLFVQLDGFSNALKRLTSLQK
What is the function of this protein?
Required with NudH/IalA for erythrocytes invasion.
What are the official names of this protein?
Invasion protein B, Invasion-associated locus protein B.
What is the protein family that this protein belongs to?
Belongs to the IalB family.
Protein: ISPDF_LEIXX
Sequence: MCTASRPRIAVIVVAAGSGTRLGAGSPKAFVTLGGRTLLERSLHAVRCMREPAQVVVVAPEERLAEAAALGEAGFGAAVDVVAGGETRQGSVAAGLGALREGVEIVLVHDAARALTPAAQFDAVVAAVDAGGAGVVPGLPVSDTIKRVGADGEVRETVDRSVLSAVQTPQGFPRDQLVAAYAAATTDETDDAELAAAAGHPVTVIPGDARAFKITTPWDLRRAEELLAGLAAPRIGFGTDTHAFDPSAELWLAGLRWEGEPGLAGHSDGDVVAHAIVDALLSAARLGDIGGVFGTGDPRFSGAHGEVFLTETRRLVEEEGFRIGNVSAQIVGNRPKFAPRRAEAETLLSRVLGAPVSVSATTTDGLGLTGRGEGVAVFATALLLAP
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: PSB1_SULIM
Sequence: MVIMGNELQLENKILKGTTTVGIKVNDGVVLAADRRASAGFFVANKMVRKVLYITDKIGITTAGSVADLQFIYDVLKNIYHYNSITKYGPISIKGIATRLANVLSATKYFPYIVQILIGGYDDQPRLFNLDYLGDITEENYVATGSGSPVAMGVLEDEYNPKMTLDEAADLAKRAVFSAIKRDSFTGTGVIVAKIHSKGHEELEFYLNKKV
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta 1, 20S proteasome beta subunit 1, Proteasome core protein PsmB 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_BORPE
Sequence: MTPRGRFITLEGVDGAGKSTHTAWMVQALRDLGLTVLATREPGGTPVGEKLRELLLSEPMALETETLLMFAARCEHVREVIAPALARGEWVVCDRFTDASYAYQGGGRQLGAARVAALEQWVHPDLQPDRTWLFDVPLDVARARLARSRQLDRFEREEDAFFERTRAAYHERARSSDGRIRIIDSSRPLEVVRAQLDSEVRELVAQAA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: KITH_BACVZ
Sequence: MYIMKQSGWLELICGSMFSGKSEELIRRVKRATYAKQEVKVFKPAIDNRYSEEAVVSHNGTSMTSHVISSSAEIWDHISESTDVIAVDEVQFFGESIIGDLSSLADKGYRVIAAGLDMDFRGEPFGVVPNLMAVAESVTKLQAVCSVCGSPASRTQRLIDGKPASYDDPVILVGASESYEARCRHHHEVPKKTD
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YMGI_ECOLI
Sequence: MSYSSFKIILIHVKNIIPIITATLILNYLNNSERSLVKQILIEDEIIVCATYLIPDI
What are the official names of this protein?
Uncharacterized protein YmgI.
Protein: YQGF_THEMA
Sequence: MDIQLFQGYGGKVIVAVDYGERKCGVAFGEILPQKSLVIPTKNLKEFIRKLKPDKIIFGLPLSMSGKYTQQTFKTVAVAFKFSKEYETYLCDERLTTKIGERISKRDDAVSAALIFQSFFENSSVCEKVTDPRKKVDLALEKVDGEVLLYEFPDPSLNIEAREVDVVTKNPVLAYFYSKNGYFVGRELWEKKYDLIISGKNCEELKKYLKENGRLVCL
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y026_CERS1
Sequence: MLAVLSPAKRLAARPALDLPADLAPSEPRLQDQADALARVARDLTAADLRRLMHISEPLARLNVARFAEFHEARNAAVPAVALFDGDTYAGLEARTMDADALRWAQERICILSGLYGLLRPLDRIQPHRLEMGTRLATERGATLYDFWGDRIAEALNARAAETGARVLVNCASVEYFTAADRAALKLPVITPTFLEERNGERKVVSFWAKRARGAMARFIAENRLDDPEDLRAFRAGGYAYEPDLSTDERPVFLRAG
What are the official names of this protein?
UPF0246 protein Rsph17029_0026.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: COBD_LEPIN
Sequence: MPWGIAISILVDLILGDPKDLPHPVRAIGKLARALEKFFRNNCSSEEIAGILTSCLVYLISFIIPFLSVQFANQLHWILGELLSIMIIYTTIAIRDMIDHSKEVYDALVQTNLPLARKKVSKIVARDTENLSESEIIRACVESTAENLVDGITTPLFYAVFGGPAWAMLYRSINTLDSLFGYKNKKYLRFGSFPARIDDLANYLPARITSYILVLSSLFLGYNFKNSLYILQRDGKKHPSPNSGLTEAAVAGALEIQLGGVNLYSGVQNIKPKLGDPKKEFQIEQILQTNKLILLSSILTFIFYILIYSGAAYFL
What is the function of this protein?
Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
What are the official names of this protein?
Cobalamin biosynthesis protein CobD.
What is the protein family that this protein belongs to?
Belongs to the CobD/CbiB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RBL_AVESA
Sequence: MSPQTETKASVGFQAGVKDYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEDNQWICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYTKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRACYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYITGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHSGTVVGKLEGEREMTLGFVDLLRDDFIEKDRARGIFFTQDWVSMPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAAANRVALEACVQARNEGRDLAREGNEIIREACKWSPELAAACEVWKAIKFEFEPVDTIDE
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YKK2_CAEEL
Sequence: MDNKKKEENPSKSDTSISLPPSSTGEALQNYTESEWNASDDPYSAELLNVKKKPNRVNVFSATEKNMETIIVTEESPPQTPLPLKPVVEHHNLARLIQKSCQLLLDKTTPDGTEVQIKLEFPDWRDTA
What are the official names of this protein?
Uncharacterized protein C02F5.2.
Protein: ANDL_EMEVA
Sequence: MRGLGGSTETALRLGSDAKDRVYRAWDGFIDFAARDNVLEVALGLIIAQAFTSVVNSFVSDIVLPLVSLLPFIMRNMDEKFAILSKGPHYQEGYNTIEQARDDGALVLAYGVFLEKIVNFLGISLTLYTLAQLYMVFSKRKIIKRTVKCKYCRKWISERALRCVNCSSWQDGREDVQ
What is the function of this protein?
Part of the gene cluster that mediates the biosynthesis of anditomin, a fungal meroterpenoid (PubMed:25216349).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide synthase andM (PubMed:25216349).  DMOA is then converted to the phthalide compound 5,7-dihydroxy-4,6-dimethylphthalide (DHDMP) by the cytochrome P450 monooxygenase andK, which is further prenylated by the prenyltransferase andD to yield farnesyl-DHDMP (PubMed:25216349).  Further epoxidation by the FAD-dependent monooxygenase andE leads to epoxyfarnesyl-DHDMP (PubMed:25216349).  The next step involves the terpene cyclase andB that converts epoxyfarnesyl-DHDMP into preandiloid A through opening of the epoxide ring followed by the cyclization of the farnesyl moiety (PubMed:25216349).  Preandiloid A is in turn oxidized at the C-3 hydroxyl group to yield preandiloid B by the dehydrogenase andC (PubMed:25216349).  The dioxygenase andA is solely responsible for the dehydrogenation of preandiloid B leading to the enone preandiloid C, as well as for the intriguing structural rearrangement to generate the bicyclo[2. 2. 2]octane core, transforming preandiloid C into andiconin (PubMed:25216349).  FAD-binding monooxygenase andJ then produces andilesin D which is reduced by dehydrogenase andI to yield andilesin A (PubMed:25216349).  Action of acetyltransferase andG followed by a spontaneous acetate elimination leads then to andilesin B, which is in turn substrate of the short chain dehydrogenase andH to yield andilesin C (PubMed:25216349).  Finally, the dioxygenase andF catalyzes the transformation of andilesin C to anditomin (PubMed:25216349).  The exact role of andL within the anditomin biosynthetic pathway has not been identified yet (PubMed:25216349).
What are the official names of this protein?
Anditomin synthesis protein L.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RK16_SOLTU
Sequence: MLSPKRTRFRKQHRGRMKGISSRGNHISFGKYALQALEPAWITSRQIEAGRRAMTRNARRGGKIWVRIFPDKPVTLRPAETRMGSGKGSPEYWVAVVKPGRILYEMGGVTENIARRAISLAASKMPKRTQFIIS
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: APT_GLUOX
Sequence: MSFQDPQPLDLKNYIREIPDFPKRGILFYDISTLIRSPDAWQVATARLARVIAAWQPDILAGIESRGFLTAAPLALRLGCGFTMLRKPGKLPGKTISLKYGLEYGEDELHIQADAIKPGQRVVVLDDLLATGGTLAASIDLLRKVGAEVVGASVLIELADLKGREKLDVPLNALMTYDE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.