PharMolix/UniProtQA huggingface dataset:
Protein: AROA_METBU
Sequence: MKVTVGRSGVHGEIFAPASKSYTHRAITVAALSKESIIHRPLISADTQSTIKACEMLGAYIEKDGDKLLISGVDGEPQTPDNVIDVGNSGTTLRFMTAIAALGQGTTVLTGDNSIRSRPNGPLLQVLNDLGVQSISTRGDGCAPIVVTGGLKGAIAKIDGSISSQFISALLLACPLTKNSTTLSIKGELKSRPYVDVTLDILEKAGAEIYLEDNQNLKFIIPGNQKYRLKEYTVPGDFSSASYLLAAAAMTDTKIKVNNLYPSMQGDAAIIDILKEMGANIYWNKEEGTVEVNGGKLHGITMDAGATPDLVPTVAVLGAVAEGETVITNAEHVRYKETDRLHAMAVELDKMGISTSEEKDKLTIKGGELKGADVHGWHDHRIVMSLTLAGMIAGDTTIDTAEAIFISYPNFFDSMRSIGADVILSEQ
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSI_SALCH
Sequence: MSEKHPGPLVVEGKLSDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAAQKLEPRHAMLLRCRLPGGVITTTQWQAIDKFAADNTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGATYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVDTFKEEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDNNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHQGEFRITANQNLIIASVPESQKAKIEKLARDHGLMNAVSAQRENSMACVSFPTCPLAMAEAERFLPSFTDKVEAILEKHGIPDEHIVMRVTGCPNGCGRAMLAEIGLVGKAPGRYNLHLGGNRIGTRIPRMYQENITEPDILASLDQLIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDFWDNLNCRMASV
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: DDL_LEPBP
Sequence: MSKIKIALLFGGISGEHIISVRSSAFIFATIDREKYDVCPVYINPNGKFWIPTVSEPIYPDPSGKTEIEFLQEFNKANAIVSPSEPADISQMGFLSAFLGLHGGAGEDGRIQGFLDTLGIPHTGSGVLASSLAMDKYRANILFEAMGIPVAPFLELEKGKTDPRKTLLNLSFSYPVFIKPTLGGSSVNTGMAKTAEEAMTLVDKIFVTDDRVLVQKLVSGTEVSIGVLEKPEGKKRNPFPLVPTEIRPKSEFFDFEAKYTKGASEEITPAPVGDEVTKTLQEYTLRCHEILGCKGYSRTDFIISDGVPYVLETNTLPGMTGTSLIPQQAKALGINMKDVFTWLLEISLS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTS1A_DANRE
Sequence: MFFISKLSLSNIHVRLTAKGLLRNLQLLSGCKLAVGFLAVDKNKSRTNSKNPQPPTNGQPDLVPPESKSRNVEYYKAQCEKKNQTIRQLENTLLSNNRRFEAVAVVIKHLYAEHDEVMKQRRDLSQELVTLREELVSSGHSCERLEQEKEDLRSAFDGVLQKVQEQHRLDLADLEERLKTFYSTEWEKVHQAYQEEADKCKAQMEQQLEEIRSKHEALKKELESSHIEEVDGLKQQFEESFKGFKQSHEKEMQNLNETLKESEETLSNQIQDLMTENDSLKEKLNAEVKRRMELAEKTQDSHTLYLEQELESLKVVLDIKNKQIHEQDKKLMQIDKLMERNVKLDECLKKLQQENEDLKARMDRHAALSRQLSTEQAVLQESLQKESKVNKRLSMENEELLWKLHNGDLNSPRKISPSPSLNLQSPRTSGMFSSPPVSPR
What is the function of this protein?
May inhibit cell proliferation.
What are the official names of this protein?
Microtubule-associated tumor suppressor 1 homolog A, Mitochondrial tumor suppressor 1 homolog A.
What is the protein family that this protein belongs to?
Belongs to the MTUS1 family.
What are the subcellular locations of this protein?
Mitochondrion. Golgi apparatus. Cell membrane. Nucleus.
Protein: PP3BA_XENLA
Sequence: MAVDIAMKFYLRSPPLRRDRVECRIARKSNEPLRPCIQTTDKTLLSELSNQENKVKKRVSFADSRGLALTMVKVYSDFDDELEIPFNISELIDNIVNLTTVEKERFVLDFVQPSADYLDFRNRLQADSVCLENCMLKDKALVGTVKVKNLAFQKCVKIRMTFDSWQTYTDYDCQYVKDTYAGSDKDTFSFDVSLPEGIQSNTRIEFAVYFECEGRIFWDSNKSLNYKIARQDHRIPSNFESRHYDPVCMSVDQYGSPRCSYGIFPELPTYSGFDKLGPYY
What is the function of this protein?
Acts as a glycogen-targeting subunit for phosphatase PP1.  Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity.  Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown (By similarity).
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 3B-A.
Protein: ATPA_STRLI
Sequence: MAELTIRPEEIRDALENFVQSYKPDAASREEVGTVTLAGDGIAKVEGLPSAMANELLKFEDGTLGLALNLEEREIGCVVLGEFSGIEEGQPVSRTGEVLSVAVAEGYLGRVVDPLGNPIDGLGEIETSGRRALELQAPTVMQRKSVHEPMETGYKAVDAMTPIGRGQRQLIIGDRQTGKTALAVDTIINQRDNWRTGDPNKQVRCIYVAIGQKGSTIASVRGALEENGALEYTTIVAAPASDPAGFKYLAPYTGSAIGQQWMYEGKHVLIIFDDLSKQADAYRAVSLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDAEGAGSMTGLPIVETKANDVSAFIPTNVISITDGQCFLESDLFNAGQRPALNVGISVSRVGGSAQHKAMKQVSGRLRVDLAQFRELEAFAAFGSDLDAASKSQLERGQRMVELLKQNQYQPMSTEDQVVSVWAGTTGKMDEVPVADIRRFEKELLEYLHRQEQGLMTSIREGGKMSDDTLQAVAEAIAAFKKQFETSDGKLLGEDAPSAAK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CCME_AZOC5
Sequence: MTRKSRRLILIGAGLGVLALAAGLILTALNDTIVFFRTPTEVAQQQIAPGARLRLGGLVEPGSVAKSGASVRFAVTDGNSKVTVAYTGLLPDLFREGQGVVAEGVLQSDGTVKADSVLAKHDERYMPREVADALKKSGHWKEGEEGGPVPPAAKTPGPQSSAAPPAVSPARSTP
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: GSH1_ECO5E
Sequence: MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTDFAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPLSMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGDISGADAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPFEKTECGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGIDKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSSELACTRVNWNRVILEGRKPGLTLGIGCETAQFPLPQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSARILRSMIDTGIGGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQEMEAADTEPFAVWLEKHA
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: DNAJ_STRAG
Sequence: MNNTEFYDRLGVSKDASQDEIKKA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity).
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_KLEP3
Sequence: MLIKMLTKVFGSRNDRTLRRMRKVVNIINGMEPAMEKLSDDELKAKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNDRCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGMSVGINMSGLPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYRKVNKIIPHLIRQEKEDSDTFTGEGHFSVDEKARQVNLTERGLVLIEELLVQEGIMEEGESLYSPTNIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVEIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKDMADLVYMTEAEKIQAIIEDIKTRTAAGQPVLVGTISIEKSEVVSRELTKAGIKHNVLNAKFHASEADIVAQAGYPAAVTIATNMAGRGTDIMLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLAAGGLHIIGTERHESRRIDNQLRGRAGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYTQRNELLDVSDVSETINSIREDVFKATIDAHIPPQSLEEMWDIEGLQERLKNDFDLELPIKEWLDKEPELHEETLRERILQSAVETYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEAMEQQRREEAERLAQMQQLSHQSDDEAAAEDLAAQTGERKVGRNDPCPCGSGKKYKQCHGRLS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: AROB_SHEPC
Sequence: MMKQIQVDLGERSYPIYIGQNLMNDSEALSRYLFKKRILIVTNETVAPLYLNQIQEVMVSFGEVESVILPDGEQFKDLTHLDAIFTALLQRNYGRDSVLVALGGGVIGDMTGFAAACYQRGIDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPQLVLIDTQCLHTLPAREFAAGMAEVIKYGIMWDGEFFQWLENNVQALKRLETEALVYAISRCCEIKADVVSQDETEQGVRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGTVLAAQTARSLGLIDESIVCRIVQLLQAFDLPVSAPESMDFDSFIQHMRRDKKVLGGQIRLVLPTGIGQADVFSQVTESTLEQVICCA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VRTF_PENAE
Sequence: MTTTTTTDDTQKLDPSASDEVIYKSWDLLIYEIWVLGIVSTWAWGCSTTEYLLPQFRANVGTNHLDVGSGTGYYLRKGGIPASTRLTLLDLERPALDLGLQRCGRSDARGLQADILQPLPVIDKFDSVSMYYLLHCIPASVEDKCAIFKHIKHNMTPDGVIHGANVLGKGVRNDGHFAAYVRRGVLKAGIFHNLDDNAYDFEHALRMNFEEVETRVVGSVFIFRASRPKLDEGDLLET
What is the function of this protein?
N-methyltransferase; part of the gene cluster that mediates the biosynthesis of viridicatumtoxin, a tetracycline-like fungal meroterpenoid with a unique, fused spirobicyclic ring system (PubMed:20534346).  The first step of the pathway is the production of the malonamoyl-CoA starter unit for the polyketide synthase vrtA (PubMed:20534346).  The aldolase vrtJ may be involved in the synthesis of the malonamate substrate for malonamoyl-CoA synthetase vrtB (PubMed:20534346).  The polyketide synthase vrtA then may utilize the malonamoyl-CoA starter unit, followed by sequential condensation of eight malonyl-CoA units to form the polyketide backbone (PubMed:20534346).  The cyclization of the last ring could be mediated by the lactamase-like protein vrtG (PubMed:20534346).  The proposed post-PKS tailoring steps are an hydroxylation at C5 catalyzed the cytochrome P450 monooxygenase vrtE, a hydroxylation at C12a catalyzed by VrtH and/or VrtI, and an O-methylation by the O-methyltransferase vrtF (PubMed:20534346, PubMed:24161266).  VrtC is then proposed to catalyze the transfer of a geranyl group synthesized by vrtD to the aromatic C ring of the tetracyclic polyketide intermediate of viridicatumtoxin to yield previridicatumtoxin (PubMed:20534346).  Finally, the cytochrome P450 monooxygenase vrtK catalyzes the spirocyclization of the geranyl moiety of previridicatumtoxin to afford viridicatumtoxin (PubMed:24161266).
What are the official names of this protein?
N-methyltransferase vrtF, Viridicatumtoxin synthesis protein F.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: GATB_CUPMC
Sequence: MQWEVVIGLETHTQLSTASKIFSGTSTAFGAEPNTQASPVDLALPGVLPVLNRGAVERAIQFGLSIGATIAPRSIFARKNYFYPDLPKGYQISQYEIPVVQGGQITIQVEGKQGVYEKTVNLTRAHLEEDAGKSLHEDFAGMTGIDLNRAGTPLLEIVTEPDMRSSAEAVAYAKALHSLVVWLGICDGNMQEGSFRCDANVSVRPVGQEKFGTRREIKNLNSFRFLQQAIDYEVQWQIAEIEDGREIVQATVLFDPDTGETRAMRTKEDAHDYRYFPDPDLMPLEIDAAWVERVKSELPELPATMQARFVSQYGLSAYDASTITATKALAAYYEAVVTNVGAASAKPAANWVMGEIASQLNREGISIDEAPVRPAQLAKLLARITDGTVSNNTAKKDVFPAMWAGESDGDADAIIAAKGLKQMSDTGELEKIIDDVLAANAKSVEEFRAGKEKAFNALVGQAMKATKGKANPAQVNELLKKKLG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: Y1237_PASMU
Sequence: MSEQLKIKAMRAAGVGCVLMLMIIALVVFMLPTGILIDYLTLAGSWVGGGTTFGILMLAALPPLTGAIFYYFWKWVLK
What are the official names of this protein?
Uncharacterized protein PM1237.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPG_RHIE6
Sequence: MPSLKDLKNRIASVKATQKITKAMKMVAAAKLRRAQEAAEAARPYSQRMNTVLANIAKAVTDADGAPVLMTGTGKDQVHLLVVCTAERGLCGGFNSQIARFARDHVRKLVAEGKTVKIFTVGKKGYDILRREFASLIVERKELREVKKIGFENADQIGKRIIEMFEAGEFDVCTLFYSEFKSVISQVPTAQQLIPAKAPEAVAEDADHAGAVYEYEPDPAAILDDLIPRNISVQIFRALLENVAGEMGAKMSAMDNATRNAGEMINKLTLSYNRQRQAQITKELIEIISGAEAL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FMP52_NEUCR
Sequence: MSTSTPTSTALIGSTGLVGSHILSTLLTSPTTSSQVQTISRRAPANPTNSSRLSPTVNADTSTWPTLLSSLVPLPTTVISSLGTTRVAAGGIANQWKIDHDLNVDLAKAAKQAGVKNFVFISSAGTRGALSTKVPYSQMKRGVEDTIQSLDFEHGIILRPGLILGEREKAQHAGQGLLYGLVRGLGRWVSLGVQDRFAQEAEVIARAAVKAAKMAEEGKAPGKWWVLEQDEIVKLGREEWKE
What are the official names of this protein?
Protein fmp-52, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the FMP52 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein.
Protein: SERC_DESOH
Sequence: MSKRIYNFNPGPAALPLSVLEEIQATFLDFAGTGMSITEVSHRSKPFDAIINDAVTRVKRLLGIGDDFKVLFVQGGASMQFAMVPMNLLPDGKSADYVNTGTWSTKAIKETKILGKTVNVAASSEDRNFAYIPKELSLDPNAAYVHITSNNTIKGTQWADFPDTKGVPIVSDMSSDILSRPLDMSKFGLIYAGAQKNIGPAGVCMVIVKNDLLEKANTGLPSMLAYKTYADSNSLYNTPPCFTIYAIDLVLKWLEETIGGLEKMDAVNREKAALLYDLFDASSFYNGTADADSRSLMNVTFRLPSEDLEKRFVEEATKNDLGGLKGHRSVGGCRASIYNAMSMEGIQALVDFMKEFERTNG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_STRP3
Sequence: MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDAVSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLDKLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEISFDDVDKVRGLDIVIVTTANTDEESRELLKGLGMPFAK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: DCDA_CAMJE
Sequence: MDYKQLKQEFNTPFYIYNFDFIKERFLNLKEAFKARKSQIFYAVKANSNLSLLQMLANLDSGFDCVSIGEVKRALKAGAKAYKIIFSGVGKTKEELRQALEYDILYINLESEAEMMLLESVAKELNLKARISIRVNPNVDAKTHPYISTGLNENKFGVEIDIARKMYLYAKNSSFLEPVGVHFHIGSQLLDISPIHEAAAIVAKLVRELKALQIDLKFFDIGGGLGVAYEKNECEPDLYDYAQGILAQLHGLDLTIGMEPGRYLVAKSGEFVCSVLYEKQNKTKRFVVVDGAMNDLIRPSLYEAYHEIILPYNQGEESLCDVVGGICESGDFFAKARSLPSTQSDDIMVIKNTGAYGFSMSSNYNTRNKVCELALEEGQVRLIRQRENFEDQIALEEKFLKA
What is the function of this protein?
Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.
What are the official names of this protein?
Diaminopimelate decarboxylase, DAP decarboxylase, DAPDC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
Protein: HIS7_JANMA
Sequence: MSTPRTAEITRNTNETQIRVAINIDGTGQQKLNTGVPFLDHMLDQIARHGLIDLDIEAKGDLHIDAHHTVEDVGITLGQAFAKAIGDKKGIRRYGHSYVPLDEALSRVVIDFSGRPGLEFHVPFTRSMIGTFDVDLTHEFFQGFVNHALVSLHIDNLRGANAHHQCETVFKAFGRALRMAAELDPRSVGTIPSTKGSL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEFI8_RAT
Sequence: MEYDEKLVRFRQAHLNPFNKHLGPRHHEQEPNEKAQEVTSEDTLPELPAGEPEFCYSERMMDLGLSEDHFSRPVGLFLASDVQQLRQAIEECKQVILELPEQSEKQKDAVVRLIHLRLKLQELKDPNEEEPNIRVLLEHRFYKEKSKSVKQTCDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISRPCVSSKVSHQAEYELNICPETGLDSQDYRCAECRAPISLRGVPSEARQCDYTGQYYCSHCHWNDLAVIPARVVHNWDFEPRKVSRCSMRYLALMVSRPVLRLREINPLLFNYVEELVEIRKLRQDILLMKPYFITCKEAMEARLLLQLQDRQHFVENDEMYSIQDLLEVHMGRLSCSLTEIHTIFAKHIKLDCERCQAKGFVCELCKEGDVLFPFDSHTSVCNDCSAVFHRDCYYDNSTTCPKCARLTLRKQSLFQEPGLDVDA
What is the function of this protein?
Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts.  Involved in bone resorption.
What are the official names of this protein?
Differentially expressed in FDCP 8 homolog, DEF-8.
What is the protein family that this protein belongs to?
Belongs to the DEF8 family.
Protein: AROC_RHIE6
Sequence: MSHNTFGHLFRVTTWGESHGPALGCVVDGCPPGLRFKLEDLQVWLDKRKPGQSRFVTQRREDDLVKVLSGVMLDADGETMTSTGTPISMLIENTDQRSKDYGEIARQYRPGHADFTYDLKYGIRDYRGGGRSSARETAARVAAGGIARLVVPGVTVRGALVQIGKHKIDRRNWDWDQVGQNPFFSPDAAIVPVWEEYLDGIRKAGSSIGAVVEVVAEGVPAGLGAPIYAKLDQDIASLLMSINAVKGVEIGNGFAAAETSGEDNADEMRMGNDGTPIFLSNNAGGILGGISTGQPVVARFAVKPTSSILTERQSIDADGKNVDVRTKGRHDPCVGIRAVPIGEAMVACAIADHYLRDRGQTGRLK
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: DER_DESOH
Sequence: MKPVVVILGRPNVGKSTLFNRLTRTQNALVDDMPGVTRDRLYGDVEWNGVFFSLVDTGGFLSGDDDFFMPHIQSQIHRAIDEADAVLLVFDGKSGISPFDREAMAFLQSASCPVFYLVNKIDSPEREVYTAEFFGLGLDNLYPVSGAHGYGVTDFLDDLVNALPETEPEPPADDMIKLAVVGRPNVGKSTLINRILGQERMIVSDVPGTTRESVDTVCEIDGRSYLLIDTAGLRRKSRVSVKLEKFSAIKTLKSLDRCDIALILVDAEEGVTDQDVTIAGYAFERGCGCIFLVNKWDLAKEQEKKAKTFYDDLQDQAKFLSFAPAVTISAATGFRVKKIFELIDAVHAQYTFNIKTGELNNIFERATRSKEPPFHKGRRLKFNYAVQVATGPPTFICFVNFPSGVHFSYKRYLINAIRRETGLDKTPIRLFFREKPGRIDFAALKPSEKRGGKKTRRK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: PYRG_ECOBW
Sequence: MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: EXBB1_VIBCH
Sequence: MESLQQLQQQLGLMAWPLFICSALTVMLLAERLFQVLLSLTVGKGAIRHALQATSPKNPKQLAELTEHFASKRPVLYRGVAMLLAHHQFDKSLREDAAGIWLQEQRHQFNSGLRLLTLIGVISPLLGLLGTVLGLIEMFKGVAATTGSITPNVLADGLGVAMYTTAAGLLIAVPAVAGAQLLSLWADRTMAKLEHTLNYVNLWLEGMTLHADASLTVVTPQEATTENL
What is the function of this protein?
Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.  Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity).
What are the official names of this protein?
Biopolymer transport protein exbB1.
What is the protein family that this protein belongs to?
Belongs to the ExbB/TolQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MENC_SHISS
Sequence: MRSAQVYRWQIPMDAGMVLRDRRLKTRDGLYVCLREGEREGWGEISPLPGFSQETWEEAQIVLLAWVNNWLAGDGELPQMPSVAFGVSCALAELADTLPQAANYRAAPLCNGDPDDLILKLADMPGEKVAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRLDANRAWTPLKGQQFAKYVNPDYRHRIAFLEEPCKTRDDSRAFARETGIAIAWDESLREPDFAFVAEEGVRAVVIKPTLTGSLEKVREQVQAAHALGLTAVISSSIESSLGLTQLARIAAWLTPDTIPGLDTLDLMQAQQVRRWPGSPLPLVDADVLEQLL
What is the function of this protein?
Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
What are the official names of this protein?
o-succinylbenzoate synthase, OSB synthase, OSBS, 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase, o-succinylbenzoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.