PharMolix/UniProtQA huggingface dataset:
Protein: PT1_SALTY
Sequence: MISGILASPGIAFGKALLLKEDEIVIDRKKISADKVDQEVERFLSGRAKASAQLEAIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQATALEELDDEYLKERAADVRDIGKRLLRNILGLAIIDLSAIQEEVILVAADLTPSETAQLNLQKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTAQVKNGDYLILDAVNNQVYVNPTNDVIEQLRAVQEQVATEKAELAKLKDLPAITLDGHQVEVCANIGTVRDVEGAERNGAEGVGLYRTEFLFMDRDALPTEEEQFAAYKAVAEACGSQAVIVRTMDIGGDKELPYMNFPKEENPFLGWRAVRIAMDRKEILRDQVRAILRASAFGKLRIMFPMIISVEEVRALRKEIEIYKQELRDEGKAFDESIEIGVMVETPAAATIARHLAKEVDFFSIGTNDLTQYTLAVDRGNDMISHLYQPMSPSVLNLIKQVIDASHAEGKWTGMCGELAGDERATLLLLGMGLDEFSMSAISIPRIKKIIRNTNFEDAKVLAEQALAQPTTDELMTLVNKFIEEKTIC
What is the function of this protein?
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS).  This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
What are the official names of this protein?
Phosphoenolpyruvate-protein phosphotransferase, Phosphotransferase system, enzyme I.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLB_PSE14
Sequence: MFLRHVIVFSLIALLTGCAGLTSREAVQGKGDPAQWREHKQQLSSLDGWQINGKVGIRAPKDSGSGTLFWLQRQDYYDIRLSGPLGRGAARLTGRPGAVALEVANQGRYEATTPETLLQDQLGWKLPVSHLVWWVRGLPAPDSKSSVTLDGDSRLASLEQDGWQVEYLSYVEQNGYWLPERVKLHGQDLDVTLVIKDWQPRKLGQ
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RRF_OENOB
Sequence: MIDLKEVKERMGKVSKAFQNELINIRAGRANPNILNKIQVEYYGAPTPLNQLASVQIPEARVLLITPYDKTSLKAIEQAIFASDLGLTPQNDGSAIRLIIPQLTEDSRKELVKQVKAEAEKAKVAARNTRHDFMSDLKKDNDLSEDSRHRTEDDIQKATDLEIKDIDRIADIKEKELMEI
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLNA_GIBFU
Sequence: MATPITSRTETLQKYLKLDQKGMIMAEYVWVDADGGTRSKSRTLPEKEYKPEDLPVWNFDGSSTNQAPGDNSDVYLRPCAVYPDPFRGSPNIIVLAECWNADGTPNKYNFRHDCVKVMDTYADDEPLFGLEQEYTLLGSDNRPYGWPAGGFPAPQGEYYCGVGTGKVVQRDIVEAHYKACLYAGIQISGTNAEVMPAQWEYQVGPCTGIAMGDQLWISRFFLHRVAEEFGAKVSLHPKPIAGDWNGGLHSNFSTKAMREEGGMKVIEEALKKLEPHHVECIAEYGEDNELRLTGRHETGSIDSFSWGVANRGTSIRVPRETAAKGYGYFEDRRPASNADPYRVTKVLLQFSMA
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_DEHMB
Sequence: MRYSRLFGKTQREIPSDAETISHQLLLRSGMIAQLTAGVYSFMPLAWRSIQKIETIIRQEMNKAGCQELAMPVLQPVEIWQQSGREAPFGQTLFHLKDRKDRNLVLGPTHEEVITDLASRYIQSYRDLPQRLYQIQAKFRDEPRPRGGLIRVREFIMKDMYSFDASPEGLDDSYQTMKQAYESVYRRCGLESMVIDADSGAIGGKASHEFMIVAESGEDSIIYCPKCSYAANAEKAVFKKKTLSKETLKDLEEVATPGQKAISDVARFLAVKPENTLKAVFYMADGKFVMAVIRGDLDINEVKLKNLLKCNDLRLAEDGEVKAAGVVAGSASPVGLKNILIVADDSVENGSNFVAGANKDGFHLKNVNCGRDFRADKMADIALAAEGSACPFCDGTFASKRGVEVGHIFKLGTFLSERFGANFTDAEGVSHPIIMGCYGMGVGRLLAAAIEQNHDEKGIIWPMPIAPYQVYICGLFLDNPVVRESAEKIYKELEAKSIEVLFDDRELTAGVKFNDADLLGIPLRLTISPRNLDKGGVEFKLRRNKESELVPLDSIVERVIATIKSESDL
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_UREPA
Sequence: MKKYDVIVIGAGHAGLEAAFATSNLNLQTALITLDEKGIGMMPCNPSIGGPAKGIVTREIDALGGIQGKAADATTMQMKILNSSKGPGVWAIRAQIDKIAYQRWFKQQIKQQKNLDLIIAEVSDLLVENNIVKGVVLSDQKIIQADYVIITTGTYLKSITHRGSVCVDEGADGTKNAKFLSDALVKLGFELIRLKTGTPARIKKDSIDFTNMILEPGTNQKIAFSHYHPVYKPYDEQLPCHIIYTNEQTHQIIRENLNKSAMYGGMISGIGPRYCPSIEDKIVKFSEKPRHQIFVEPESYELDSMYLGGFSTSMPIDVQEKMIRSLPGLENCEILKYAYAIEYDAIDPTQLYPSLESKLVNNLFFAGQINGTSGYEEAAAQGLMAAINVNQKYQNKEPVILGRDQAYIGVMIDDIVTKGVVEPYRLLTSRAEHRLALRNDNADDRLMKIGFEIGLLKPEVYDQYLNNLKQIKEILNWLKTTTVGQIDDLKFTTLKTNSYLIDYLKRPEIKLNDLLIYCPIKIEDEQIINKVQIQVKFEGYIKNQEENLKQLKRLNNIKLHAIVDYKEVPNISLETIDKLNKIKPLDLEQASRISGVNLTDIAMIKYYLERIKND
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEZT_STRPN
Sequence: MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAGKTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLVTKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEELYIINPNQARATPKEHHDFIVNHLVDNTRKLEELAIFERIQIYQRDRSCVYDSKENTTSAADVLQELLFGEWSQVEKEMLQVGEKRLNELLEK
What is the function of this protein?
Acts as a corepressor of its own operon with PezA; it is not clear if it binds DNA alone.
What are the official names of this protein?
Toxin PezT, UDP-N-acetylglucosamine kinase, UNAG kinase, Zeta toxin.
What is the protein family that this protein belongs to?
Belongs to the zeta toxin family.
Protein: RCA_ORYSJ
Sequence: MAAAFSSTVGAPASTPTNFLGKKLKKQVTSAVNYHGKSSNINRFKVMAKELDEGKQTDQDRWKGLAYDISDDQQDITRGKGFVDSLFQAPTGDGTHEAVLSSYEYLSQGLRTYDFDNTMGGFYIAPAFMDKLVVHISKNFMTLPNIKVPLILGIWGGKGQGKSFQCELVFAKMGINPIMMSAGELESGNAGEPAKLIRQRYREAADIIKKGKMCCLFINDLDAGAGRMGGTTQYTVNNQMVNATLMNIADNPTNVQLPGMYNKEDNPRVPIIVTGNDFSTLYAPLIRDGRMEKFYWAPTRDDRVGVCKGIFRTDNVPDEDIVKIVDSFPGQSIDFFGALRARVYDDEVRKWVSDTGVENIGKRLVNSREGPPEFEQPKMTIEKLMEYGYMLVKEQENVKRVQLAEQYLSEAALGDANSDAMKTGSFYGQGAQQAGNLPVPEGCTDPVAKNFDPTARSDDGSCLYTF
What is the function of this protein?
Activation of RuBisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase; EC 4. 1. 1. 39) involves the ATP-dependent carboxylation of the epsilon-amino group of lysine leading to a carbamate structure.
What are the official names of this protein?
Ribulose bisphosphate carboxylase/oxygenase activase, chloroplastic, RA, RuBisCO activase.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO activase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: RS4_SHEB9
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDSKCKLETAPGQHGARKPRLSEYGTQLREKQKVRRIYGVLEKQFRNYYKDAARTKGNTGENLLQLLETRLDNVVYRMGFGATRAESRQLVSHKSIMVNGRVVNIPSFKVSANDVVSIREKSRTQARIKAALEVAAQREKPTWVEVDNAKMEGAFKRVPERSDLSAEINEQLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: Y2025_MYCTU
Sequence: MTHDHAHSRGVPAMIKEIFAPHSHDAADSVDDTLESTAAGIRTVKISLLVLGLTALIQIVIVVMSGSVALAADTIHNFADALTAVPLWIAFALGAKPATRRYTYGFGRVEDLAGSFVVAMITMSAIIAGYEAIARLIHPQQIEHVGWVALAGLVGFIGNEWVALYRIRVGHRIGSAALIADGLHARTDGFTSLAVLCSAGGVALGFPLADPIVGLLITAAILAVLRTAARDVFRRLLDGVDPAMVDAAEQALAARPGVQAVRSVRMRWIGHRLHADAELDVDPALDLAQAHRIAHDAEHELTHTVPKLTTALIHAYPAEHGSSIPDRGRTVE
What are the official names of this protein?
Probable cation efflux system protein Rv2025c.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UVRC_PSEF5
Sequence: MTEQFDPSAFLSTCSGRPGVYRMFDSDARLLYVGKAKNLKNRLSSYFRKTGQAPKTAALVARIAQIETTITANETEALLLEQTLIKEWRPPYNILLRDDKSYPYVFLSDGDFPRFSIHRGAKKQKGKYFGPYPSAGAIRESLSLLQKTFMVRQCEDSYYKNRTRPCLQYQIKRCKAPCVGLVEPEVYAEDVRHSVMFLEGRSNALTDELSTAMEAAASTLDFEKAAELRDQISLLRRVQDQQSMEGGTGDVDVVAAFVNPGGACVHLISVRGGRVLGSKNFFPQVGIEEDVAEVMSAFLGQYFVSSPERDLPSELIVNVVHEDFPTLIAAIDELRGRELTISHRVRGTRARWQQLAVTNAEQALSARLANRQHVAARFEALAEVLNLDEPPQRLECYDISHSSGEATVASCVVFGPEGPLKSDYRRYNIEGVTAGDDYAAMHQALTRRFSKLKDGEGKLPDILLVDGGKGQLSMARDVLNELAVPDLILLGVAKGATRKAGFETLYLNDAAHEFTLKGDSPALHLIQQIRDEAHRFAITGHRARRGKTRRTSTLEGVAGVGPKRRRDLLKHFGGLQELSRASIDEIAKAPGISKKLAELIYANLHSE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOVO_CHRPC
Sequence: LAAVSVDCSEYPKPACTMEYRPLCGSDNKTYGNKCNFCNAVVESNGTLTLNHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: AREG_HUMAN
Sequence: MRAPLLPPAPVVLSLLILGSGHYAAGLDLNDTYSGKREPFSGDHSADGFEVTSRSEMSSGSEISPVSEMPSSSEPSSGADYDYSEEYDNEPQIPGYIVDDSVRVEQVVKPPQNKTESENTSDKPKRKKKGGKNGKNRRNRKKKNPCNAEFQNFCIHGECKYIEHLEAVTCKCQQEYFGERCGEKSMKTHSMIDSSLSKIALAAIAAFMSAVILTAVAVITVQLRRQYVRKYEGEAEERKKLRQENGNVHAIA
What is the function of this protein?
Ligand of the EGF receptor/EGFR.  Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.
What are the official names of this protein?
Amphiregulin, AR, Colorectum cell-derived growth factor, CRDGF.
What is the protein family that this protein belongs to?
Belongs to the amphiregulin family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SMS_LAMFL
Sequence: AAAAPGAAGGAQLPLGNRERKAGCKNFFWKTFSSC
What is the function of this protein?
Somatostatin inhibits the release of somatotropin.
What are the official names of this protein?
Somatostatin.
What is the protein family that this protein belongs to?
Belongs to the somatostatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYP_FRAP2
Sequence: MKATQTLIATTKELPKEAVLTSHQYMLKAGLIKKLASGIYTWMPIGLKVLQKIQNIVREEMNKAGASELLLPSVLPSELLQETHRWDKFGPELLKLKDRHERDFCYGPTHEEPIVDMARDTIKSYKQLPLNLYQIQTKFRDEIRPRFGVMRAREFIMKDAYSFHENSECLHNTYNKMHETYCNILDKIGLVYRPVRADTGAIGGDNSHEFQVLANAGEDIICYSNGSDYAANIELATYAKPDLSTRAVSENTITKIHTPNIKTIEKLCTELDFDIKKTIKTMVIKDAKGNFFALVIRGDHELNETKINKLEQIVAPYTLATKDEIFSIFNANPGSLGIVNCPVQIIADYSAMMIEDICCGANEDDYHFTNVNWGRDITSYQIADIRNVVTGDISPDNNGTLELTNGIEVGHIFELEDVYSKPMNANIIGQDGKSKPMLMGCYGFGVSRVMAAAIEQSHDENGIIWPETIAPYQVAILPINYNKSESVKQTADKLYQELLVKGIDVILDDRGARPGVMFADADLIGFSHHVVIGDRLLEQGLVEYKNRKTQEKQEIRLEKLFDILA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_I54A2
Sequence: MASQGTKRSYEQMETDGERQNATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAFDERRNKYLEEHPSAGKDPKKTGGPIYKRVDRKWMRELVLYDKEEIRRIWRQANNGDDATAGLTHMMIWHSNLNDTTYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRKTRIAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGPAVASGYDFEKEGYSLVGIDPFKLLQNSQVYSLIRPNENPAHKSQLVWMACNSAAFEDLRVSSFIRGTKVIPRGKLSTRGVQIASNENMDTMESSTLELRSRYWAIRTRSGGNTNQQRASAGQISIQPTFSVQRNLPFDKTTIMAAFTGNAEGRTSDMRAEIIRMMESAKPEEVSFQGRGVFELSDEKAANPIVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: QUEA_CHLPM
Sequence: MKVSDFDYSLPEERIAKYPPDNRGATRLLVLNRHTGSVQHARYSNLEAFLGYGDLLVINTTKVVRARLFAVKQTGAAIELMLLEKHEGPQNLALYRGRLKKGDRLLAHGHELIVEELAGQGVARLSVEGIESVHALFQNHAEVPIPPYLKRDAEAVDRERYQTVFAEHPGSVAAPTASLNMTPELLLKLEKGGVATAVMTLHVGLGTFLPIRTETMEEHVMHREFYSIPARTIEQIHETRRSGGRVVALGTTVTRALEHAATRISAFSGSDPLVGEADIFIHPGYSFQTIDALLTNFHAPRSTVLMLTAAFAGADHLRAAYREAVEKRYDFLSYGDSMLIS
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H14G1_CYRHA
Sequence: MKVVLLVCLVWMMAMMELVSCECWSQADCSDGHCCAGSSFSKNCRPYGGDGEQCEPRNKYEAYSTGCPCEENLMCSVINRCQSA
What are the official names of this protein?
U8-theraphotoxin-Hhn1f, U8-TRTX-Hhn1f, Hainantoxin-XIV-7, HNTX-XIV-7.
What is the protein family that this protein belongs to?
Belongs to the AVIT (prokineticin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL34_MESH7
Sequence: MKRTYQPNKRKHLKTHGFRARMSTADGRKILAARRAKGRKRLTVSDK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: PPA3_ARATH
Sequence: MTYIYRDTKITTKSTIPFLIFFLFCFSNLSMATLKHKPVNLVFYVYNLIIIFSSHSSTAELRRLLQPSKTDGTVSFLVIGDWGRRGSYNQSQVALQMGEIGEKLDIDFVISTGDNFYDNGLTSLHDPLFQDSFTNIYTAPSLQKPWYSVLGNHDYRGDVRAQLSPMLRALDNRWVCMRSFIVNAEIVDLFFVDTTPFVDKYFIQPNKHVYDWSGVLPRQTYLNNLLKELDVALRESVAKWKIVIGHHTIKSAGHHGNTIELEKHLLPILQANEVDLYVNGHDHCLEHISSVDSNIQFMTSGGGSKAWKGGDVNYVEPEEMRFYYDGQGFMSVHVSEAELRVVFYDVFGHVLHHWKKTYKEALYFAS
What are the official names of this protein?
Purple acid phosphatase 3.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1362_CHESB
Sequence: MKITWYGHSAFRIEAGGAKILIDPFLSGNPTWKEGWEGPAEGVTHVLLTHGHGDHLGDTLDILKKTGAMLVANAEISSYYGAQGVEGSRINPGNHGGTVDCGGFTTTFVNALHSSSFTKDGSNIYLGNPHGLVLHFPSDKTVYHMGDTDIFGDMALIEELHQPQIGLVPIGDRYTMGGAVAALACRRFFRFEAVIPCHYGTFPIIDQTAEKFIEGMEGAETKVLTPPPGQEVDL
What are the official names of this protein?
UPF0173 metal-dependent hydrolase Meso_1362.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: HSP83_DROPB
Sequence: MPEEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYXSXTDPXKLXXXXXXXXXXIPNKTAGTLTIIDTGIXMTKSDLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLIADRVTVTSKNNDDEQYVWESSAGGSFTVKADNSEPLGRGTKIXLYIKEDQTDYLEESKIKEIVNKHSQFIGYPXKXXXEKERXKEVSDDEADDEKKDDEAKKDMDTDEPKIEDVGEDEDADKKDKDGKKKKTIKEKY
What is the function of this protein?
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction.  Undergoes a functional cycle that is linked to its ATPase activity.  This cycle probably induces conformational changes in the client proteins, thereby causing their activation.  Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.  Required for piRNA biogenesis by facilitating loading of piRNAs into PIWI proteins (By similarity).
What are the official names of this protein?
Heat shock protein 83, HSP 82.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYCB_GEOSK
Sequence: MSRKVTKYSAVLAVSLFAAALAGCGSENKEGTVGTGPGGVATVGDSACVQCHSAVTEALTGESLIAQYQKSSPHNTAGLGCESCHGGGAQHNGVGPIPFAQPDASRCADCHDGTTAVATNSDTAFAESRHNIQTIRSGATCRRCHTHEGAVLSNIAGYTGDLATLEDTVNQNKVPLVSSYSQISCATCHEHGGGLRTIKATNGAAGPVVNWDPNNNRTVDQFDLCTSCHNMYSYNGSTLLTNGVPVNGVATGTVGHHETTWYRIIATTHFDNYSTGPQAGAGASGTNAKVEGYVLRRTGANPCFDCHGHEAKTNTRPGRDATIHTDWAKSAHAGGLLTAKYNAVGALTGAAAVNAAMNAYVDDTTAIAWTHYNWDASSRGSCQRCHTATGAANFMSNPAGYDPTGAGNSFSHLQGWSAANGSKQNELLYCWGCHTNAGTGELRNPGAITENYAGVNSTSTGTTGTAVTISYPDIAGSNVCMTCHLGREAGENIKAITDADGILGFVNSHYLAAGGQLFGKTGYEYATRSYAKPTFFAHDKIGTAAAPGTGTNGPCAGCHMTTPNSHSFLPVTKDGTGAVTAITSTACATCHAGAYALTPEALTAEEEEYVASLEALKAALAGKGILFFNAHPYFYRDTNANGIGDPGELVSSNAFTNWAGVYGLALWKDVMGAAFNANLLIHDPGGYAHNRFYVKRLIWDSIDFIYDGVLNNDVTAAIDAQVTATRLDSATATAAKAYLGTTRP
What is the function of this protein?
Involved in anaerobic respiration with Fe(3+) as terminal electron acceptor.  Acts as an electron-transport mediator in the dissimilatory reduction of Fe(3+).
What are the official names of this protein?
C-type polyheme cytochrome OmcB, Outer membrane c-type cytochrome B.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: CSN1_DICDI
Sequence: MEDMQVEKNTEGSSSSSSNNNNNNSISNEFDLETYINNYSGFTKIHRLIFIADNCKQLEVEAYNMALKEVQKTPNLELYNTIINKSHGILELDPVYIENLSKKNSLQLDKLEQDLNTAKSNMVKDSIRFAQNDLGEFYYKIGDHQNALKCFIRTRDYCTTSKHVLAMCFNIIKLGVDTQNYTHAPSYIAKAEQSPDLDNVSNAKLRSVNGLYNLDGSRYKLAARKFIETPFEQSNVFSDIISPQDIAYYGGLCALATFDRNELKKKVIDDPMFKNYLELVPELRELINDFYNTKYGSCLKYLDKMKPILLLDIHLYKHVEILYQRIRSKALVQYFSPYQSVDMNIMASAFNTTVTLLEKEISKLIMENEIQARIDSHNKRLYARKADQRTTTFEKTVQVGSDFQNSSNSLLLRLEMLNNNISTVSNRKDNERGNWENPHHHHQMQHQMFGLFNNNNKF
What is the function of this protein?
Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity.
What are the official names of this protein?
COP9 signalosome complex subunit 1, Signalosome subunit 1.
What is the protein family that this protein belongs to?
Belongs to the CSN1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: E41L5_CANLF
Sequence: MLSFFRRTLGRRSMRKHAEKERLREAQRAATHIPAAGDSKSIITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLECPFDTAVQLAAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGETKIGLFFWPKITRLDFKKNKLTLVVVEDDVQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPVQKSSHRSGFIRLGSRFRYSGKTEYQTTKTNKARRSTSFERRPSKRYSRRTLQMKASTAKPEELSVHNNVSTQSNGSQQAWSVRSTLPVIPSVPSGPVLAEIENLPRNPGSNQYDRKWVSAASDCCQRGGNQWNTRALSPPQPAHRNYTDFVHEHNVKNTGVHHDVHFPGHAAMTEI
What is the function of this protein?
Plays a role in the formation and organization of tight junctions during the establishment of polarity in epithelial cells.
What are the official names of this protein?
Band 4.1-like protein 5, Erythrocyte membrane protein band 4.1-like 5.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein. Photoreceptor inner segment.
Protein: PUR5_STRM5
Sequence: MTNTPSSAPSPLTYRDAGVDIDAGNELVERIKPLVKRSFRPEVMGGLGGFGALFDLSNKYREPVLVSGTDGVGTKLKLAHQLNRHDTIGIDLVAMCVNDVLVQGAEPLFFLDYFATGKLDIDTAAAVVGGIANGCTEAGCALIGGETAEMPDMYAPGEYDLAGFTVAAVEKSELKDGASVAAGDVLIGIASSGPHSNGYSLVRRIYDRAGRPAELELEGGVKLVDALMAPTRLYVKPILSLLKSHGAAIHGMAHITGGGLTENIIRVVPEGLGLDIQASSWTLPPVFQWLQKEGAVADSEMWRTFNCGIGFVLIVAPDQVAAVSEAVKAQGLDHWTIGQVVTAEGAERVHIG
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRM1_ASPFU
Sequence: MLFSRSGRSIFPLLPPYAAHAPNPNQGHIIALPPDGLTPYLGLRARLSQVWINRWTILLLLVLVRVLLAASGLQADMSTAKREALSACTSVESMGSSMASMPHYLSQGVNELTATGVEKAVSGLKSMLMLTITGVEELVLFIIKVLYQTYLCLFTLAVRGSVHVAVGVIKEAADFLNSTVKEVGDDIGKAVSTFESAFNKFLDGVNTVASAFGASVPTLDLNSSISTLENLQLPSSIDQGLDKLNSSLPTFDEVNNFTQTVLRTPFEEVKKLVNESLGTYTFDRSLLPVPAKEQLTFCEGSNGIDSFFDSVTDLVMKARKIFIAILIVAATLACVPMAWQEIRRWRSMKERSQLVRKEAHDPMDVVYIVSRPYTAAAGIKAASRFSNSRRQILVRWAIAYATTPAALFVLCLGVAGLLSCLCQYLLLQAVEKTVPELSTQVGAFADKVVDSLQNASAEWANDANGVIGHMSQDLNENVFGWVNTSTTALNDTLNTFVDKTTGVLNDTFGGTLLYEPLMDVFGCLIGLKVQGIQKGLTWVHDHAHIDFPLLPNDTFSRGAAASISSNSSNPSDSFLADAGDQTSNKITEVVIRVVNKVEDGIRTETIISGVIILIWVFIALIGIVRALTLFWVRDRNRGEGGGARVNHHLSDAGGFIDVPLTAVSNTNTDARSMPPPAPAPRYEASTSTVVASRAVPVSSTHHEDEKLGFAGERQYGSALKVDGAADLRGSSYVEYDMEKR
What is the function of this protein?
Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.
What are the official names of this protein?
Plasma membrane fusion protein prm1.
What is the protein family that this protein belongs to?
Belongs to the PRM1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.