PharMolix/UniProtQA huggingface dataset:
Protein: GLR21_ARATH
Sequence: MKRENNLVLSLLFFVIVFLMQVGEAQNRITNVNVGIVNDIGTAYSNMTLLCINMSLSDFYSSHPETQTRLVTTVVDSKNDVVTAAAAALDLITNKEVKAILGPWTSMQAQFMIEMGQKSQVPIVTYSATSPSLASIRSQYFFRATYDDSSQVHAIKEIIKLFGWREVAPVYVDDTFGEGIMPRLTDVLQEINVRIPYRTVISPNATDDEISVELLRMMTLPTRVFVVHLVELLASRFFAKATEIGLMKQGYVWILTNTITDVLSIMNETEIETMQGVLGVKTYVPRSKELENFRSRWTKRFPISDLNVYGLWAYDATTALALAIEEAGTSNLTFVKMDAKRNVSELQGLGVSQYGPKLLQTLSRVRFQGLAGDFQFINGELQPSVFEIVNVNGQGGRTIGFWMKEYGLFKNVDQKPASKTTFSSWQDRLRPIIWPGDTTSVPKGWEIPTNGKRLQIGVPVNNTFQQFVKATRDPITNSTIFSGFSIDYFEAVIQAIPYDISYDFIPFQDGGYDALVYQVYLGKYDAVVADTTISSNRSMYVDFSLPYTPSGVGLVVPVKDSVRRSSTIFLMPLTLALWLISLLSFFIIGLVVWVLEHRVNPDFDGPGQYQLSTIFWFSFSIMVFAPRERVLSFWARVVVIIWYFLVLVLTQSYTASLASLLTTQHLHPTVTNINSLLAKGESVGYQSSFILGRLRDSGFSEASLVSYGSPEHCDALLSKGQAEGGVSAVLMEVPYVRIFLGQYCNKYKMVQTPFKVDGLGFVFPIGSPLVADISRAILKVEESNKANQLENAWFKPIDESCPDPLTNPDPNPSVSFRQLGFDSFWVLFLVAAIVCTMALLKFVYQFLKENPNQRNLRVLWEKFNEPDQKSYIKDVTKCQCSSGQGMPKNGQEGANAVNNGN
What is the function of this protein?
Glutamate-gated receptor that probably acts as non-selective cation channel.  May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells.
What are the official names of this protein?
Glutamate receptor 2.1, Ligand-gated ion channel 2.1, AtGLR3.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PIAS4_HUMAN
Sequence: MAAELVEAKNMVMSFRVSDLQMLLGFVGRSKSGLKHELVTRALQLVQFDCSPELFKKIKELYETRYAKKNSEPAPQPHRPLDPLTMHSTYDRAGAVPRTPLAGPNIDYPVLYGKYLNGLGRLPAKTLKPEVRLVKLPFFNMLDELLKPTELVPQNNEKLQESPCIFALTPRQVELIRNSRELQPGVKAVQVVLRICYSDTSCPQEDQYPPNIAVKVNHSYCSVPGYYPSNKPGVEPKRPCRPINLTHLMYLSSATNRITVTWGNYGKSYSVALYLVRQLTSSELLQRLKTIGVKHPELCKALVKEKLRLDPDSEIATTGVRVSLICPLVKMRLSVPCRAETCAHLQCFDAVFYLQMNEKKPTWMCPVCDKPAPYDQLIIDGLLSKILSECEDADEIEYLVDGSWCPIRAEKERSCSPQGAILVLGPSDANGLLPAPSVNGSGALGSTGGGGPVGSMENGKPGADVVDLTLDSSSSSEDEEEEEEEEEDEDEEGPRPKRRCPFQKGLVPAC
What is the function of this protein?
Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor (PubMed:12511558, PubMed:12631292, PubMed:12727872, PubMed:15831457, PubMed:15976810, PubMed:22508508, PubMed:32832608).  Mediates sumoylation of CEBPA, PARK7, HERC2, MYB, TCF4 and RNF168 (PubMed:12511558, PubMed:12631292, PubMed:12727872, PubMed:15831457, PubMed:15976810, PubMed:22508508).  Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53/TP53 pathway, the Wnt pathway and the steroid hormone signaling pathway (PubMed:11388671).  Involved in gene silencing (PubMed:11248056).  In Wnt signaling, represses LEF1 and enhances TCF4 transcriptional activities through promoting their sumoylations (PubMed:12727872, PubMed:15831457).  Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation (PubMed:21965678).  Binds to AT-rich DNA sequences, known as matrix or scaffold attachment regions (MARs/SARs) (By similarity).  Catalyzes conjugation of SUMO2 to KAT5 in response to DNA damage, facilitating repair of DNA double-strand breaks (DSBs) via homologous recombination (HR) (PubMed:32832608).  Mediates sumoylation of PARP1 in response to PARP1 trapping to chromatin (PubMed:35013556).
What are the official names of this protein?
E3 SUMO-protein ligase PIAS4, PIASy, Protein inhibitor of activated STAT protein 4, Protein inhibitor of activated STAT protein gamma, PIAS-gamma.
What is the protein family that this protein belongs to?
Belongs to the PIAS family.
What are the subcellular locations of this protein?
Nucleus, PML body. Note=Colocalizes with SUMO1 and TCF7L2/TCF4 and LEF1 in a subset of PML (promyelocytic leukemia) nuclear bodies.
Protein: IPSA_CORGL
Sequence: MGRKQQYGTLASIAAKLGISRTTVSNAYNRPEQLSAELRQRILDTAEDMGYLGPDPVARSLRTRRAGAIGVLLTEDLTYAFEDMASVDFLAGVAQAAGDTQLTLIPASPASSVDHVSAQQLVNNAAVDGVVIYSVAKGDPHIDAIRARGLPAVIADQPAREEGMPFIAPNNRKAIAPAAQALIDAGHRKIGILSIRLDRANNDGEVTRERLENAQYQVQRDRVRGAMEVFIEAGIDPGTVPIMECWINNRQHNFEVAKELLETHPDLTAVLCTVDALAFGVLEYLKSVGKSAPADLSLTGFDGTHMALARDLTTVIQPNKLKGFKAGETLLKMIDKEYVEPEVELETSFHPGSTVAPI
What is the function of this protein?
Plays a role in the regulation of cell wall biogenesis.  Inositol-dependent transcriptional activator of ino1, which encodes inositol phosphate synthase.  Also regulates other target genes, which are most likely involved in the synthesis of inositol-derived cell wall components and mycothiol.  Acts by binding to a conserved palindromic motif within the promoter regions.
What are the official names of this protein?
HTH-type transcriptional regulator IpsA.
Protein: YR727_MIMIV
Sequence: MNNMDYDPRSMGSYGPNYNNFNPNFGKIRRHKNTSYPGYNGFDPSDGPMNGPMGGPMGGPMNGPMNGQMGGPMNGSMNGPMNGPMNGPMNGQMGGPMNGPMGGPINGPMNGPRGRQMNGPNNGPMGGPMNGPMNGPNNNQFNGPMNGPNEYYSPEDSDGSDYSDSNPNEFDSDDDDIDLSYFQKRQYDKPTYHKFEVTDEYLADYLLRKFGLDKDKVVRSIQKNKKDEFKAMILNYFYKENPKIKHQSINNQYKLFRKWNKSGLKIKIDDLETYYENKVKPHMH
What are the official names of this protein?
Uncharacterized protein R727.
What are the subcellular locations of this protein?
Virion.
Protein: SYI_PSEU2
Sequence: MTDYKATLNLPDTAFPMKAGLPQREPQTLQRWDSIGLYQKLREIGKDRPKFVLHDGPPYANGNIHIGHAVNKILKDMILRSKTLAGFDAPYVPGWDCHGLPIEHKVEVTHGKNLSADRTRELCRAYASEQIEGQKSEFIRLGVLGDWSNPYLTMNFANEAGEIRALAEMVKGGFVFKGLKPVNWCFDCGSALAEAEVEYQDKKSSTIDVAFPIADEAKLAAAFGVPSLGKPASIVIWTTTPWTIPANQALNVHPEFEYALVDVGDKLLVLAAELVESCLARYKLEGTVIATTTGQALELINFRHPFYDRLSPVYLADYVELGAGTGIVHCSPAYGVDDFTICKQYGLSNDDIISPVQSNGVYVESLEFFGGQFIFKANQNIIDKLVEVGSLMDTETISHSYMHCWRHKSPLIYRATAQWFVGMDKQPESGETLRKRAVKAIEDTEFVPAWGQARLHSMIANRPDWCISRQRNWGVPIPFFLHKESGDLHPRTVELMEEVAQRVEKEGIEAWFKLDASELLGDEAGKYDKISDTLDVWFDSGTTHWHVLRGSHPMGHESGPRADLYLEGSDQHRGWFHSSLLTGCMLDDHAPYRELLTHGFVVDENGRKMSKSLNNVVAPQKVNDSLGADIMRLWVSATDYSGEMAVSDQILQRSADAYRRIRNTARFLLSNLTGFNPATDILPAEEMLALDRWAVDRTLLLQRELLEHYGEYRFWNVYSKIHNFCVQELGGFYLDIIKDRQYTTAANSTARRSCQTALFHISEALVRWIAPILAFTADELWQFLPGERNESVMLNTWYDGLTEMPADFDMDRAYWERIMAVKTSVNKEMENLRAAKAIGGNLQAEVTLYAEESLVADLSKLSNELRFVLITSTASVAPLASAPADAVVTEVAGLKLKVLKSSHAKCARCWHHREDVGVNPEHPEICGRCVDNISGAGEVRHYA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYIG_MOUSE
Sequence: MIGLVTKFQIYCSHSPWYGTSHTSIYFCYPGMLGQSATHGSLSSRTLFFPSSRGQKCGPQQALLCPQPTILGWCCFKLVIWVLSQSSEAIAVGQSLSPGTNIPVTVCPLYLMPCFKNPVLLGLMPTLIQHKFISTRFHPP
What are the official names of this protein?
Putative uncharacterized Ig-region protein.
Protein: PG195_VACCW
Sequence: MRSLIIVLLFPSIIYSMSIRQCEKTEEETWGLKIGLCIIAKDFYPERTDCSVHLPTASEGLITEGNGFRDIRNTDKL
What are the official names of this protein?
Protein OPG195.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG195 family.
Protein: HEM3_MYCTO
Sequence: MIRIGTRGSLLATTQAATVRDALIAGGHSAELVTISTEGDRSMAPIASLGVGVFTTALREAMEAGLVDAAVHSYKDLPTAADPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLVGTSSPRRAAQLRALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDDVTETLEPVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAPVGAIAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFELGARELMWGVRH
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: RPOA2_FRATH
Sequence: MALENLLHPTNIKIDEYAKNATKFSFEALERGVGYTLGFALKQTMLYSIAGACVTSIKINDGKVTSLEDVIPCDETVADIILNVKSLSVTLAEDVETGTITFELSGSEEEIFSEEAKLSEGLAITEEVFICSYNGGKKLKIEAKVEKGVGFRPAQDNFKDGEFLLDATFSPVVFCDFEIKDARVGRRTDLDKLELNIKTNGNVNCEEALRLAATKIQNQLRNIVDIEEINKGIFVEDPKDINPILLKHVEELNLTARSSNCLKAVNIRLIGELVQKTENELLKAPNFGKKSLTEIKDKLSELGLSLGTLIENWPQDL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha 2, RNAP subunit alpha 2, RNA polymerase subunit alpha 2, Transcriptase subunit alpha 2.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: GNAI1_HUMAN
Sequence: MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades.  The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state.  Signaling by an activated GPCR promotes GDP release and GTP binding.  The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal.  Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins (PubMed:8774883, PubMed:18434541).  Signaling is mediated via effector proteins, such as adenylate cyclase.  Inhibits adenylate cyclase activity, leading to decreased intracellular cAMP levels (By similarity).  The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane.  Required for normal cytokinesis during mitosis (PubMed:17635935).  Required for cortical dynein-dynactin complex recruitment during metaphase (PubMed:22327364).
What are the official names of this protein?
Guanine nucleotide-binding protein G(i) subunit alpha-1, Adenylate cyclase-inhibiting G alpha protein.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(i/o/t/z) subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cell cortex. Membrane; Lipid-anchor. Note=Localizes in the centrosomes of interphase and mitotic cells, but not in centrosomes during cytokinesis. Detected at the cleavage furrow or the midbody (PubMed:17635935). Localized at the plasma membrane throughout mitosis. Colocalizes with RIC8A and RGS14 at the plasma membrane.
Protein: PCS_RHIME
Sequence: MKFFNYRRVPYAEIRAFSVHILTASGSFLAFLGVVAAAEHRFVDMFWWLGLALLVDGIDGPIARKVQVKEVLPNWSGDTLDNVIDYVTYVLLPAFALYQSGMIGEPWSFVAAGAIVVSSAIYYADMGMKTDEYFFSGFPVVWNMVVFTLFVIQASEVTASIVVFLSVILTFLPINFLHPVRVKRLRPLNLGIFLVWSVLGMYALLLHFETPPWVVVGVVATGLYLYVIGFILQIFPKLGRA
What is the function of this protein?
Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP.
What are the official names of this protein?
Phosphatidylcholine synthase, PC synthase, PCS, CDP-diglyceride-choline O-phosphatidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HUTG_VIBCH
Sequence: MNPNFTTEHTWQGRHDPEDGQAGRRVHHIACPIQVGELANQEPGVALIGFECDAGVERNKGRTGAKHAPSLIKQALANLAWHHPIPIYDLGNIRCEGDELEQAQQECAQVIQQALPHARAIVLGGGHEIAWATFQGLAQHFLATGVKQPRIGIINFDAHFDLRTFESELAPVRPSSGTPFNQIHHFCQQQGWDFHYACLGVSRASNTPALFERADKLGVWYVEDKAFSPLSLKDHLTQLQHFIDDCDYLYLTIDLDVFPAASAPGVSAPAARGVSLEALAPYFDRILHYKNKLMIADIAEYNPSFDIDQHTARLAARLCWDIANAMAEQVQSIRHP
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: TSAD_LEPBJ
Sequence: MIGMGIETSCDETSIGIIRDGKELLSLGIFSQIDLHKPYGGIVPEIASRAHLEKINLLLEETMEEAKIRFEDLSYVAVTSSPGLTGSLMVGAQMARCINMVYETPILPVCHLQSHFAVLHLEGVPTEFPVLGLLLSGGNSAVYILQEFGRMELVGDTMDDALGEAFDKVAGLLDLPYPGGPHIEAKANEYIPTPDEKPILPLLLRNLPQGEVSFSFSGLKTAVMVLLEKQKEVSKEQICWNFQNSAFDLVERNLKRAVAKTGIRKVFAAGGVLANTTLQKRLEVWAGKNSVELFTPKKKIYCTDNGAMVASLGYHLFRKGYKKGVDFTVNPSRQEIFS
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBI6_YEAST
Sequence: MPFNHNSKAKRPKFLLDLQIKELVNIPQSSGYCYTKWRLKDGTGTSGHKVALDGEHQTTSTQSRGTTKHVHVQHHRAQWNYSLDKPILVKLHLDKNGRFLKKILVLDVFFEFADANSSLTSSSSPNGKVKKTTYANATALTATGNNSYSQKITGKLLLGTVDIDITEYVKEDETPTTNRFLLKHSKVNSIINVSLQLKLVRGSYEDFNISKSFTNGQLANYRPGINTILDNTSELSSPTSTTNQMSPKNTFSNFNGIGTTVAKPGTNATGNSTSIKSPTSTNHKSSEMTTKPGLSTTISSSMSPLIESLYQKTFKLPWDPRPGEFTPRECVEDILQGGNGWAKNEKGINLIDLQALRLNEMEEEYYNPNYGNNLGNKASSWPPNPSDDGYSTMGKREYLEKKQNWSHMSRAQRAKLRTHNDEDNENTANDKGSDKDNNSVEDNNPTDFLTDRIRENKNWSIITPSG
What are the official names of this protein?
Uncharacterized protein YBL086C.
What is the protein family that this protein belongs to?
To S.pombe SpCC1494.08c.
Protein: RL4_BREBN
Sequence: MPKVALYNQTGSQVGEIDLADSVFGIEPNSAVLYDAIVMQQASQRQGTHDVKNRSEVRGGGRKPWRQKGTGRARQGSIRSPQWKGGGVVFGPTPRKYGYKLNRKVRRLALKSALSTKVQNNELLVLEALNFAAPKTKEMTAVLSSLKVDRKVLIVTSEYDQNVALASRNIPGTKIVDAAGINVLDLVAHDKVIVTREAVAKVEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: GLPE_PSEA7
Sequence: MSDTFQRIAPEQARQLRENGAQVVDIRDPQSYALGHISGSRHIDNHSVVDFIAAADLDAPLVVVCYHGNSSQSAAAYFIQQGFSDVYSLDGGFELWRSVYPADTSTGEAE
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_RICTY
Sequence: MQTIEQQITNIIEESLTDMGFELVLVKFKGVNTKVVEILIDSLNGNKISIEDCTNVSRTISAILDVEDLIEDAYSLEVSSSGIERKLVKFENYNRFLGREVKVKLKALLNGKTLYQGKIIKAENNKIYLKCAEQEVLIDFNLIKNANLVLTEEVFKKLLGS
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_STRPI
Sequence: MSKKLTFQEIILTLQRFWNDQGCMLMQAYDNEKGAGTMSPYTFLRAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEKLGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAEVTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFDKFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVAKTFVAERKRLGYPLLDEETRAKLLAEDAE
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_EXIS2
Sequence: MILVIDVGNTNIVLGVYDEQTLLQHWRIATDRTRTTDEYGMLVKALFRDAELNVEDIEGIVLSSVVPPVVFPLENMCVRYFNRRPFVIGPGIKTGLDLKVDNPREVGADRIVNAVAATVKYDGPLIIVDFGTATTYCYIDAQKRYYGGIISPGVMVSTEALYNKAAKLPRIEIAKPQSTIGRNTVHAMQSGTYFGYVAQVDGLVHRMKEEMGEATVIATGGLARLISEESATIKIVDPFLTLDGLRIIYERNK
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_MYXXD
Sequence: MNLNDVIKGPLITEKLDKAREKFRQYSFIVDRKATKHDVARAVETLFKVTVEGVNTNIVRGKIKRVGRSIGKRPNFKKAVVTLKQGDSIELFEGGAA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: TR112_DICDI
Sequence: MKILTHNMMACTKKQCMGKGFPLKVESTEQIVLEQEFNYEFTKNIYPKLDWLGIAEISIKFNIPIQLDTTKHSLEDEEFLKTLHNLLCNLKVITGSLTCPNCQRVYPIDKGIPNMLLREDEIYQEIKE
What is the function of this protein?
Acts as an activator of both RNA and protein methyltransferases.
What are the official names of this protein?
Multifunctional methyltransferase subunit TRM112-like protein, tRNA methyltransferase 112 homolog.
What is the protein family that this protein belongs to?
Belongs to the TRM112 family.
Protein: AATM_PIG
Sequence: MALLHSGRVLSGVASAFHPGLAAAASARASSWWAHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRYVTVQTISGTGALRIGANFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLHSYRYYDPKTCGFDFTGALEDISKIPAQSVILLHACAHNPTGVDPRPEQWKEMATLVKKNNLFAFFDMAYQGFASGDGNKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPMYSNPPVNGARIASTILTSPDLRQQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHIVDQIGMFCFTGIKPEQVERLTKEFSIYMTKDGRISVAGVTSGNVGYLAHAIHQVTK
What is the function of this protein?
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA).  As a member of the malate-aspartate shuttle, it has a key role in the intracellular NAD(H) redox balance.  Is important for metabolite exchange between mitochondria and cytosol, and for amino acid metabolism.  Facilitates cellular uptake of long-chain free fatty acids.
What are the official names of this protein?
Aspartate aminotransferase, mitochondrial, mAspAT, Fatty acid-binding protein, FABP-1, Glutamate oxaloacetate transaminase 2, Kynurenine aminotransferase 4, Kynurenine aminotransferase IV, Kynurenine--oxoglutarate transaminase 4, Kynurenine--oxoglutarate transaminase IV, Plasma membrane-associated fatty acid-binding protein, FABPpm, Transaminase A.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Cell membrane.
Protein: RLMH_ECOSE
Sequence: MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRGKNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLAAELERWKLDGRDVSLLIGGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBB2_BORSA
Sequence: MVEWTDSERAIITSIFSNLDYEEIGRKSLCRCLIVYPWTQRYFGAFGNLYNAETIMANPLIAAHGTKILHGLDRALKNMDDIKNTYAELSLLHSDKLHVDPDNFRLLADCLTVVIAAKMGSAFTVETQVAWQKFLSVVVSALGRQYH
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta-2, Beta-2-globin, Hemoglobin beta-2 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: ENOL1_ARATH
Sequence: MKSRSLKLREAHKVGGSAAFCSILWDHKAEHFVTSSSSDPSISVHDGLSTSTLPPTILRHHQDGVTSLALSNDSTLLASGSIDHCVKLYKFPSGEFQTNITRFTLPIRVLAFNGSGSLLAAAGDDEGIKLINTFDGSIVRVLKGHKGPVTGLDFHPNGELLASIDTTGTVLCWELQNGVVSFTLKGVAPDTGFNTSIVNIPRWSPDGRTLAVPGLRNDVVMYDRFTGEKLFALRGDHLEAICYLTWAPNGKYIATSGLDKQVLLWDVDKKQDIDRHKFEERICCMSWKPNGNALSVIDAKGRYGVWESLVPSSMLSPTVGVPDIVPKKRNEILDFDDEVEEEIYRASESLDDAMGDSDDGESHHTSRKRLRKKTLIDEDVDDAYEELNDGSSLPSASEYRKKSHRGHREKQGARSGAFKGISASTKYKMQSSFQPGATPPEPGKRTFLCYNMLGCITTIEHEGNSRIETDFHDTGRGPRVSSMIDIYGFTMASINETGCVFANPCKGEKNMSVLMYRPFRSWASNSEWTMRFEGEEVKVVANGSGWVAAVTSLNLLRVFSEGGLQKHILSLDGPVVTAVGCKDHLAVVTHVSDCLPSNEQVMEFRVFNISKMTQELKGRVALTPGSRLTWIGFSEEGSLSSYDSEGVLRVFTSQYGGSWIPVFSTSKEKKQEENYWVVGLNTSSLYCIACKYAEMFPQVTPKPILTILDLSLPLASSDLGAASLENELILKQLRLYETQRKVDDMALVGVDTTALEDEAFDLEVSQDKCILRLISSCCSSDSFARASELMELLTLEKSMRAAITLVTKLKLPFLAEKFSSILEERLLEEASEAAVTNPALNPNGEVVTRVESKVQNPPASIQTSENTEAVMKSSATKLSAPTLLKKSKVSEGLKLGKEQTKKDKSDDAKIKEIKKLNLKNPVNNVNKEDKGQEKEVNQGEARRSSNPFLKSTV
What is the function of this protein?
Participates in maintaining the H3K27me3 mark at target genes by interacting with LHP1-PRC2 complexes during replication, thus contributing to H3K27me3 inheritance.
What are the official names of this protein?
Protein ENHANCER OF LHP1 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASTE_PSEPG
Sequence: MLALGKLLELTLTDHEPAEKTQVTPKGARLRWLGEGALEVRPAESEDCGLDLLLSAGIHGNETAPIELLERLLHGVANGKIKPRARLLFLFGNPVAIRKGERFIEQDINRLFNGRHELSSGFEALRAAELEQFARVFFSKPGRSRLHYDLHTAIRGSKIEQFALYPYKEGRKHSRRELARLAAAGMEAVLLQSKSSITFSAFTYEQLDAEAFTLELGKARPFGQNEQVNLDKLEERLIRIIEATEPEGESSLDGLQLFSVSREIIKHSDSFHLHLPADIENFSELSKGYLLAEDLAEMRWVVEEEGARIIFPNPKVRNGLRAGILIVPDSGQRLG
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: RL17_CLOB8
Sequence: MAGHRKLGLPTDQRRAMLRNLVTSLLKHGKIETTETRAKETRSIAEKMITLGKRGDLHARRQVLSYVQEELVVKNLFDNVAPKYTERNGGYTRIIKKGPRRGDGAEIVILELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: HEM3_BURP6
Sequence: MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRTLSKVGGKGLFVKELESALADGRADLAVHSLKDVPMVLPEGFALAAVMSREDPRDAFVSNDYASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAAGLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAERAVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRRVSDALERQGARAIVDALVAASAQAQKGGA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.