PharMolix/UniProtQA huggingface dataset:
Protein: SELD_TRIL1
Sequence: MTNKKIKLTQTVKAAGUAAKLGPEGLADALAGLNRPADPRLIVGPETSDDGGVYCLTPEIALIESCDVITPPADAPRAFGRIAAANALSDIYAMGGRPLTAMNLAFFPACSLQPEVLGEVLAGGQDALNEAGCCLVGGHTVEDDELKYGLSVTGTVHPEQVLRNSTARPGDCLLLTKPLGSGILSTAVKGEMATVEQEAEAVAWMSLLNRAAAELMLRYTPSACTDITGFGLIGHSCEMALGSGVTIRLYLDAVPLMQGVTDQVADGMVPAGCYRNRSYYLSRIDAGDCDPERLLPLFDPQTSGGLLIALQPGAAALFQAEAAENSIFCVLIGDVLPRAELPVIVV
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: NU4LM_HYLLA
Sequence: MPLIYMNITLAFAISLLGMLIYRSHLMSSLLCLEGMMLSLFIMSTLMALNTHSLLINIMPVVLLVFAACEAAVGLALLVSISNTYGLDHIHNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MCH1_ASPFU
Sequence: MAGPDQHYEPAIDKRDFDDHRPLLHDIDTGIDGTGDGRLRSDSRLSAFRNLDGGSDGLLNDVVDEIVERDRRKMAMEVMRVCSFAVGVISCLGAGSITAFSLYGPLFLTRLHYSQLQVNAVSIAAEISMYLPVPLFGYLCDRYTPSPLALLSGLVFGGGYLLAAFAYRSGPLPEAGGEGWPPWVMVVAFVAIGTATSCMYLAAVTTCAKNFGRGKHKGIMLAVPIAGFGLSGMWQSQVATYLLCERREDGSRGDVDVFRYFLFLALFLFCLGVIGTFGLRIVDEEEDQYIDEAVEELERSGLLEESEFFRPRSEVQAAYGTFSDAADGDAPGPELSLTLSEEEREAARLEKEREEEERRKKNWLLNFETRLFLQDQTMWWLAVGFFLVTGPGEAYINNLGTIIQTLTPELHPPNAPSPAGLPSTHVTIIALTSTIARLLTGSLSDFFAPPATHLFPANIESGRRSSQSGPTAKRPTLSRLAFLLPSALLLSLGYLLLSSPLPLQHPGLSHVTTALIGLGYGSAFSLVPIIISVVWGVENFGTNWGIVAMVPAAGAAMWGVIYSRGYQDATDGGNGSPDGQCHGWRCYGFWAVGCTLSVWVAVVAWILAWRGWRRRGVVV
What is the function of this protein?
Probable transporter.
What are the official names of this protein?
Probable transporter mch1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: THIM_ECOSM
Sequence: MQVDLLSSAQSAHALHLFHKHSPLVHCMTNDVVQTFTANTLLALGASPAMVIETEEASQFAAIASALLINVGTLTQPRAQAMRAAVEQAKRSQTPWTLDPVAVGALDYRRRFCLELLSHKPTAIRGNASEIMALAGVANGGRGVDTTDAAANAIPAAQTLARETGAIVVVTGEVDYVTDGHRIVGIHGGDPLMTKVVGTGCALSAVVAACCALPGDTLENIAFACHWMKQAGERAVARSEGPGSFVPHFLDALWQLTQEVQA
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: SLU7_CANAL
Sequence: MPKYQPKNGELNPYIPRYILETPRYQQDIINKSPEQEDAQDQTTTAHDPLAHQRKTGEIIDNSIAQSGTGIKDEFKGTIRVEENESYDSKRDRWYGYSTEEWLTHLKNWNDKKQSRKHASAQDNDDSDDTDYELELIELELDKKDMKKNIKKDPMEKMLRDRQDIPAYIYNITSNPNNKIRIEYDPKSRLAKDSAKGFLNKRNQFVKKLTGDGDELMKLQKMAQELDNEHEKDRKLAKLKQEFYGEENPKTVPQTDLSLSLEASPTLMMLKSKQLQNEKLAKSIQSKQEVMEKYNASTESDEKESKKTGHLEDKLFLNHKYIYGSYYENGKWGYKCCKQFDKNSRCTATD
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor SLU7.
What is the protein family that this protein belongs to?
Belongs to the SLU7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FIN_BACSU
Sequence: MALHYYCRHCGVKVGSLESSMVSTDSLGFQHLTNEERNDMISYKENGDVHVLTICEDCQEALDRNPHYHEYHTFIQ
What is the function of this protein?
An anti-sigma factor for sporulation specific sigma-F factor, by antagonizing sigma-F it allows the switch to sigma-G factor and progression to the late sporulation development stages (PubMed:21037003).  Might stabilize or process Holliday junction intermediates, although this may be due to polar effects on the downstream mfd gene (PubMed:15317759).
What are the official names of this protein?
Anti-sigma-F factor Fin, Suppressor of recU and recB SubA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_CORGB
Sequence: MSNSNSGKVRVAVVYGGRSSEHSVSCVSAGAIMAHLDPEKYDVIPVGITVDGAWVVGETDPQKLTLIDRTMPEVEHREEVRPSLDPAHRGEFHFSDGSLYATADVIFPVLHGRFGEDGTVQGLFALSDIPVVGPGVLASAAGMDKEYTKKLMAAEGLPIGREVILRDRTELTEAEKNLLGLPVFVKPARGGSSIGISRVTAWEDFNKAVGLARAHDEKVIVESEIVGSEVECGVLQYPDGRIVASVPALLSGTESGAGGFYDFDTKYLDNVVTAEIPAPLDEKTTELIQSLAVESFQALACEGLARVDFFVTANGPVLNEINTMPGFTPISMYPQMFTASGVAYEELLDVLVQQALHRDN
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_RHOPA
Sequence: MSNMEQDRWSRVKGRLRSSVGEDVYSSWFARMDLESVHDESVHLSVPTRFLKSWIQTHYSDKVLSCWQAELPEVNRVDLTVRSPVRCATPAKEVPAPVESRRDEQRPSAERSNGATPVSANHDALGGSPLDPRLTFASFVVGRSNTLAHAAAKQVAEGRRGDPVMFNPLYIHSGVGLGKTHLLQAVTWAGNAGTERKVLYLTAEKFMYGFVAALKTQTSLAFKEALRGIDVLVIDDLQFLQGKTTQAEFCHTLNALIDAGRQVVVAADRPPADLESLDERVRSRLAGGLVVEMAPLGEDLRLGILRSRVVAARTHHASFDVPQPVLEYLARTITHNGRDLEGAINRLLAHSKLNNQPVTLEMAEHEVRDLIRPSEPKRIKIEDIQRIVARQYNVSRSDLLSSRRTANVVRPRQVAMYLAKTLTLRSLPEIGRRFGGRDHTTVLHAVRKIEGLVSKDTTLSDEVESLKRQLQE
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_SINFN
Sequence: MMKGRSLSAEDRARLETAIGYQFAEKERLDRALTHSSARNARASNYQRLEFLGDRVLGLCVAELLFQTFLDANEGELSVRLNQLVSAESCARVADELSLHEYIRTGSDVKKITGKHMMNVRADVVESLIAAIYLDGGLEAARRFVLRHWTDRAASADGARRDAKTELQEWAHAKFGAAPRYRTDDRSGPDHDPRFTVTVEVDGIAPETGTDRSKRGAEQIAAMRLLEREGVWQKRSAGN
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SENP2_MOUSE
Sequence: MYRWLAKVLGTILRLCERPAPGARALLKRRRSSSTLFSTAVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVSSACNGTRNVAPSGEVFSNSSSCELMSSGSCSSMLKLGNKSPNGISDYPKIRVTVTRDQPRRVLPSFGFTLKSEGYNRRPSGRRHSKSNPESSLTWKPQEQGVTEMISEEGGKGVRRPHCTVEEGVQKDEREKYRKLLERLKEGAHGSTFPPTVSHHSSQRIQMDTLKTKGWVEEQNHGVRTTHFVPKQYRVVETRGPLCSMRSEKRYSKGKADTEKVVGLRFEKEGTRGHQMEPDLSEEVSARLRLGSGSNGLLRRKISVLEIKEKNFPSKEKDRRTEDLFEFTEDMEKEISNALGHGPPDEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYMNLLVERSKKQGYPALHAFSTFFYPKLKSGGYQAVKRWTKGVNLFEQELVLVPIHRKVHWSLVVMDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNTDLNLLEWTHYSMKPHEIPQQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQLL
What is the function of this protein?
Activates transcription.
What are the official names of this protein?
Sentrin-specific protease 2, Axam2, SUMO-1 protease 1, SuPr-1, SUMO-1/Smt3-specific isopeptidase 2, Smt3ip2, Sentrin/SUMO-specific protease SENP2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C48 family.
What are the subcellular locations of this protein?
[Isoform 1]: Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=Shuttles between cytoplasm and nucleus. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Cytoplasmic vesicle. Note=Found in the cytoplasm and in cytoplasmic vesicles, together with axin. SUBCELLULAR LOCATION: [Isoform 3]: Nucleus, PML body.
Protein: TIG_PHOLL
Sequence: MQVSVETTQGLGRRVTITVPAADVEKAVSSELVNVAKKVRIDGFRKGKVPMNVVKQRYGASVIQDVLSDLMQRNFINAIIEQKINPAGAPSYAPEQFKNGEDFTYSVEFEVYPEIELKDLESIEVEKPVVEVKDEDVDAMLETLRKQQANWKETEEAVGAEDRVTVDFNGSVDGEEFEGGKASDFVLAMGQGRMIPGFEEGIVGHKAGEEFTIDVNFPEDYHAENLKGKAAKFAITLKKVEQRELPEFNEEFIKRFGIADGTVDGLRAEVRKNMERELKNAVRNRIKSQVIDGLVKVNEIDVPAAIVDSEIDVLRRQSAQRFGGNEKQALELPRELFEEQAKRRVVVGLLLGEVISSNELKADEERVKALIEEMASAYEAPQEVIEFYGKNQELMNNVRNVALEEQAVEVLLGKAKVSEKETTFNELMNQNQMA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: PUNA_GEOSE
Sequence: MNRTAIEQAAQFLKEKFPTSPQIGLILGSGLGVLADEIEQAIKIPYSDIPNFPVSTVEGHAGQLVYGQLEGATVVVMQGRFHYYEGYSFDKVTFPVRVMKALGVEQLIVTNAAGGVNESFEPGDLMIISDHINNMGGNPLIGPNDSALGVRFPDMSEAYSKRLRQLAKDVANDIGLRVREGVYVANTGPAYETPAEIRMIRVMGGDAVGMSTVPEVIVARHAGMEVLGISCISNMAAGILDQPLTHDEVIETTEKVKADFLRFVKAIVRNMAKN
What is the function of this protein?
The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.  Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.
What are the official names of this protein?
Purine nucleoside phosphorylase 1, PNP 1, Inosine phosphorylase, Inosine-guanosine phosphorylase, Purine nucleoside phosphorylase I, PNP I, Pu-NPase I.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family.
Protein: DCTA_CAUVN
Sequence: MKSIYVQVLIAIVLGVLVGAIWPQIGVALKPLGDGFIKLIKLVIAPVIFCTVAGGIARMGDMKAFGRVGVKALIYFEVVSTLALVIGLVVGRLIQPGAGFNIDPATLDASIAAGYVEKAQHGEGMVAYLLHLIPDTFIGAFADGNLLQVLVIAILTGFACVRMGDFGEKVAHVLDETSKLFFGIIHIVVRLAPIGAFGAMGFTIGKYGVEALVQLGALVATFYVTSLLFVLVVLGGIAWVSGFSIFRFLAYIREELLIVLGTSSSESVLPQMMEKLENAGARRSVVGLVIPTGYSFNLDGTNIYMTLATLFLAQATNTPLSLGQELALLGVAMLTSKGASGVTGAGFITLAATLAVVPDIPIAALAILVGVDRFMSECRALTNLVGNGVATLVVARWEGALDRQRLDRVLRGAPATE
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AHPF_ECOLI
Sequence: MLDTNMKTQLKAYLEKLTKPVELIATLDDSAKSAEIKELLAEIAELSDKVTFKEDNSLPVRKPSFLITNPGSNQGPRFAGSPLGHEFTSLVLALLWTGGHPSKEAQSLLEQIRHIDGDFEFETYYSLSCHNCPDVVQALNLMSVLNPRIKHTAIDGGTFQNEITDRNVMGVPAVFVNGKEFGQGRMTLTEIVAKIDTGAEKRAAEELNKRDAYDVLIVGSGPAGAAAAIYSARKGIRTGLMGERFGGQILDTVDIENYISVPKTEGQKLAGALKVHVDEYDVDVIDSQSASKLIPAAVEGGLHQIETASGAVLKARSIIVATGAKWRNMNVPGEDQYRTKGVTYCPHCDGPLFKGKRVAVIGGGNSGVEAAIDLAGIVEHVTLLEFAPEMKADQVLQDKLRSLKNVDIILNAQTTEVKGDGSKVVGLEYRDRVSGDIHNIELAGIFVQIGLLPNTNWLEGAVERNRMGEIIIDAKCETNVKGVFAAGDCTTVPYKQIIIATGEGAKASLSAFDYLIRTKTA
What is the function of this protein?
Serves to protect the cell against DNA damage by alkyl hydroperoxides.  It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.
What are the official names of this protein?
Alkyl hydroperoxide reductase subunit F, Alkyl hydroperoxide reductase F52A protein.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
Protein: ROT1_ASHGO
Sequence: MVYVSWSAAALLCASFFSTVVLAQSAKDLYGTWSAKSNQVFTGPGFYNPADELLIEPSLPGISYSFTEDGFFEMATYRVSGNPRNLACPSAVMTFQHGKYEILANGTLILRPFEVDGRQLVSEPCVDKGVSTYLRYSQVETFQRFAVELDEYHGKHALHLFQFDGSPVQPLYLAYRPPLMLPTITLNPTDHAGATATAGPGHRKRSLGELVRAGLQDKHKTTAVRNPSLFNAAFYWWCSAGVIAAGTVLFFMV
What is the function of this protein?
Required for normal levels of the cell wall 1,6-beta-glucan.  Involved in a protein folding machinery chaperoning proteins acting in various physiological processes including cell wall synthesis and lysis of autophagic bodies (By similarity).
What are the official names of this protein?
Protein ROT1.
What is the protein family that this protein belongs to?
Belongs to the ROT1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: RPOB_AROAE
Sequence: MAYSYTEKKRIRKSFAKRAAVLNVPFLLATQIESFASFLQADTPPPSRLNHGLQAAFTSIFPISSHSGNARLEFVQYMLGEPAFDVKECQQRGLTFASPLRARVRLVILDRDAPKETVKEVKEQEVYMGEIPLMTTTGSFVINGTERVIVSQLHRSPGVFFEHDRGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDALYFRVDRRRKMPATILLRAIGMGPEEILATFHDFDAFHLRGNEAAFELVPDRLRGDVAKFDITDGAGNVIVARDKRITAKHIRELDQAGVKMISVPDEFLLGRIIARNIVDAETGEIVARANDEITEDLLDKLRDAGVKDLETLYVNDLDRGAYISQTLRIDETADQWAARVAIYRMMRPGEPPTEDAVEALFQGLFYSEERYDLSSVGRMKFNRRAYPEKIEDKAPSWLKRFYETVGPRGEEGPATLSNEDILAVIGVLVELRNGRGEIDDIDHLGNRRVRSVGELAENQFRAGLVRVERAVKERLSQAESDNLMPHDLINAKPISAAIKEFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLAVYAQTNRHGFLETPYRKVVDSKVTDQIDFLSAIEEGQYVIAQANAEIDADGMLEGDLVSCRHKGEFALSTADQVQYMDVAPGQIVSVAASLIPFLEHDDANRALMGANMQRQAVPCLRPEKPLVGTGIERTVAVDSGTAVQAMRGGIVDYVDANRIVVRVNDDETLAGEVGVDIYNMIKYTRSNQNTNINQRPVVKVGDHIGKGDVIADGASTDLGELALGQNMLVAFMPWNGYNFEDSILISERVVAEDRFTSIHIEELTVVARDTKLGPEEITRDIASLGEAQLSRLDESGIVYIGAEVDAGDVLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVSSGMNGTVIDVQVFTREGIERDKRAQSIIDDMLRSFKTDLADQMRIVERDAFARIRRLIVGQKANGGPKKLLKGTAITGEYLDSLEFYHWFDIRMADEELAAQLEAIREGLEKTRKDFDQAFEIKKKKLTQGDELPPGVQKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSRIVPIEDMPHMADGTPVDIVLNPLGVPSRMNIGQILETHLGWASKALGNKIGTMLRANAAAAEVRELLEHIYNDNGRPEDMGSLKDDEVIELASNLSKGVPFATPVFDGAKEEEIEAMFELAGLQPGGQVTLYDGRTGDAFDRQVTVGYKHVLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVTGRTKVYESIVKGEHKIDAGMPESFNVLVKEIRSLAIDIDLDTY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: CH60_STRP3
Sequence: MAKDIKFSADARAAMVRGVDMLADTVKVTLGPKGRNVVLEKAFGSPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVHEGLKNVTAGANPIGIRRGIETATATAVEALKAIAQPVSGKEAIAQVAAVSSRSEKVGEYISEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFILITDKKVSNIQDILPLLEEVLKTNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKAPGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATMTALGQAAKITVDKDSTVIVEGSGSSEAIANRIALIKSQLETTTSDFDREKLQERLAKLGGGVAVIKVGAPTETALKEMKLRIEDALNATRAAVEEGIVAGGGTALITVIEKVAALELEGDDATGRNIVLRALEEPVRQIALNAGYEGSVVIDKLKNSPAGTGFNAATGEWVDMIKTGIIDPVKVTRSALQNAASVASLILTTEAVVANKPEPAAPAPAMPAGMDPGMMGGF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXT_HERA2
Sequence: MTVGVLALQGAFIEHETMLQGLGVATLQVRLPEQLVQVERLIIPGGESTTIGKLLVRFDLLEPIQQRAAEGMPIWGTCAGMILLAKEIAEGRVEGQPALGLMDITARRNAFGRQVDSFETNLQVPVLGEAPFHAVFIRAPQIDKVGEAVETLASLDDGRIVAARQGKLLATAFHPELTGDARFHELFLGL
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: LEUD_LEUCK
Sequence: MEAFIKETGRAVVIPNDSINTDIILPKQFLKNILKTGFGPHLFYDWRYLADGKINPKFELNKPEHAGATVLITGVDFGSGSSREHAVWALTDYGFRAVIGGSFSDIFYMNATKNGLLPIVLPEAERQILRDIKPDETITIDLPNQIVTYNNNQFHFDINPQWQAKFINGEDDIDVTMKFEAAITAFEKKQPNFD
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: SAR1A_PIG
Sequence: MSFIFEWIYNGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHPRLMESKVELNALMTDETISNVPILILGNKIDRTDAISEEKLREIFGLYGQTTGKGNVTLKELNARPMEVFMCSVLKRQGYGEGFRWLSQYID
What is the function of this protein?
Involved in transport from the endoplasmic reticulum to the Golgi apparatus.  Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation.  SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity).
What are the official names of this protein?
GTP-binding protein SAR1a.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. SAR1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Golgi apparatus.
Protein: TILS_FRAT1
Sequence: MSISKSLVLNEIKKFSPSHIIIGYSGGVDSSVLLNISKELDIPLIAIYINHNLHRDSLKWQIHCQQTCQKYNLQFISHSLDKVPKGESFEAWASKQRMAFFQKIMQQYSKPLLLLGHHQDDQAETFLIQAIRGSGLAGLAGIPHYKELHHGGVLRPLLKYSKIEIEGFAKLNNISYIYDDSNEDIKYRRNLIRNQIIPILQQVNPNISQTLSRSANICAESNNILQKLLTERLQSISQDTNLIISELIKLDDDIQKNLLHLWFKQNTQQSLKSKQIKELHLAVNNPSTGWQIDISNYYQIHIQYNQLIIKYPTTINDISKEDIISWLSKNLNEEIDLTKIVIRDRKPDDKCKYRGRNKPNKLKILFQELQIPTTERSKAKIILKDQQIIAVYPFFICG
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF3_PROMH
Sequence: MKGGKRIQSTRQNRINGEIRAHEVRLTGLDGEQIGVVSLKEALEKAEEAGADLVEISPNAEPPVCRIMDYGKFLYEKSKTLKEQKKKQKVIQVKEVKFRPGTDEGDYQVKLRNLIRFLEDGDKAKVTLRFRGREMAHQQIGMEMLNRIREDLDELASVESFPNKIEGRQMIMVLAPKKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_CORA7
Sequence: MANLPSDFSYSEDHEWINATADSVVGSTVRIGITSVATDRLGEVVFAELPAVGDTVEHGETCGEVESTKSVSDLYSPVTGTVTAVNEGVHDDYAVINNDPFGEGWLFEVEVTEAGELMTADEYASANGVD
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: SPON2_MOUSE
Sequence: MENVSLALGRALWVFLLAMIGSTTSQPLGGESVCTARPLARYSITFIGKWSQTAFPKQYPLFRPPAQWSSLLGAAHSSDYSMWRKNEYVSNGLRDFAERGEAWALMKEIEAAGEKLQSVHAVFSAPAIPSGTGQTSTELEVHPRHSLVSFVVRIVPSPDWFVGIDSLDLCEGGRWKEQVVLDLYPHDAGTDSGFTFSSPNFATIPQDTVTEITASSPSHPANSFYYPRLKSLPPIAKVTFVRLQQSPRAFAPPSLDLASRGNEIVDSLSVPETPLDCEVSLWSSWGLCGGPCGKLGAKSRTRYVRVQPANNGTPCPELEEEAECAPDNCV
What is the function of this protein?
Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons.  Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria.  Binds bacterial lipopolysaccharide.  Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens.
What are the official names of this protein?
Spondin-2, Mindin.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: Y1679_METJA
Sequence: MIEEEITLKIPKSIVNQIDELIKEGYFSSRDEFVRYAVRESLTEIAISKKMSREECKKIWEEYKIRKKDIKIDEKEIEELLDEVDKEWKKWKKLKLK
What are the official names of this protein?
Uncharacterized protein MJ1679.
Protein: LEXA_SHIBS
Sequence: MKALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVIEIVSGASRGIRLLQEEEEGLPLVGRVAAGEPLLAQQHIEGHYQVDPSLFKPNADFLLRVSGMSMKDIGIMDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKKQGNKVELLPENSEFKPIVVDLRQQSFTIEGLAVGVIRNGDWL
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: IF2_MICAN
Sequence: MSNTKVRIYDLSKELNLDNKDILDICDQLNIEYKSHSSTISEEDAQRIKAIAAKGLASSTSKNSTGQRESASPAEEKKQKILALHKHNRPETGEEGESYPGQAGSSAKPTLISPPRPPVKPLVAPPGRDEAAEKTPPTAAEMLSHSPSVKETPTETPLVPEAAPTLIAPPNRPSLTPKPRPETASGRPEPRSKNAPGSNDRPRGEKRERGESENAPSPERRVGLAKPEKPTLNRKPDGKSPKLAEPAREVRETVELKRPVRPGLPAKISATSEEETDTTKKSGVDGTEIDTDTGLLGADGPKKLKRPTMPPRMAKKSTWEEEEEEEKKAAKTAKTAGKNKRRTQALFEDDDDLESELSGLINTPSFTLSTARPPKPPTAKAAPPGTPTAVKVKRPSKPTAHTGSPKSERQEPQEEKRPESIVVTGSLTVRDLSELMKVPETEIIRTLFFKGMAVNITQTLDVDTIEMIARDFEIAVETPSTQSAAIKTTEMIDVSDWESLQRRPPVVTIMGHVDHGKTTLLDSIRKTKVAQGEAGGITQHIGAYHVDVEHNGKPEQIVFLDTPGHEAFTAMRARGARVTDIAVLVVAADDGVQPQTKEAISHARAAEVPIVVAINKVDKPSANPDRIKQELTEQGLVAEDWGGETIMVPVSALRGENLDNLLEMILLVAEVEELVANPDRLAKGTVIEANLDRTKGPVATLLVQNGTLRVGDSIVAGSVFGKIRAMIDDRGQKVEAATPSFAVEILGLSDVPAAGDEFDVYESEKEARSIADQRAIERRNTRLQQALSSRRVSLSTLSIQAQEGQLKELNLILKADVQGSVEAILGALKQLPQNEVQIRVLLASPGEITETDVDLAAASGAVVVGFNTTLASGARASADREGVDIRDYNIIYKLLDDIQGAMEGLLDPEEVEEHLGFAEVRAVFTVGRGAVAGCYVQSGKLVRNRFLRVRRGKEIVYQGVLDSLKRMKEDAREVATGFECGVGVSKFNDWKEGDIIEAYEMVMKRRTLSS
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.