PharMolix/UniProtQA huggingface dataset:
Protein: DGLB_HUMAN
Sequence: MPGMVLFGRRWAIASDDLVFPGFFELVVRVLWWIGILTLYLMHRGKLDCAGGALLSSYLIVLMILLAVVICTVSAIMCVSMRGTICNPGPRKSMSKLLYIRLALFFPEMVWASLGAAWVADGVQCDRTVVNGIIATVVVSWIIIAATVVSIIIVFDPLGGKMAPYSSAGPSHLDSHDSSQLLNGLKTAATSVWETRIKLLCCCIGKDDHTRVAFSSTAELFSTYFSDTDLVPSDIAAGLALLHQQQDNIRNNQEPAQVVCHAPGSSQEADLDAELENCHHYMQFAAAAYGWPLYIYRNPLTGLCRIGGDCCRSRTTDYDLVGGDQLNCHFGSILHTTGLQYRDFIHVSFHDKVYELPFLVALDHRKESVVVAVRGTMSLQDVLTDLSAESEVLDVECEVQDRLAHKGISQAARYVYQRLINDGILSQAFSIAPEYRLVIVGHSLGGGAAALLATMLRAAYPQVRCYAFSPPRGLWSKALQEYSQSFIVSLVLGKDVIPRLSVTNLEDLKRRILRVVAHCNKPKYKILLHGLWYELFGGNPNNLPTELDGGDQEVLTQPLLGEQSLLTRWSPAYSFSSDSPLDSSPKYPPLYPPGRIIHLQEEGASGRFGCCSAAHYSAKWSHEAEFSKILIGPKMLTDHMPDILMRALDSVVSDRAACVSCPAQGVSSVDVA
What is the function of this protein?
Lipase that catalyzes the hydrolysis of arachidonic acid (AA)-esterified diacylglycerols (DAGs) to produce the principal endocannabinoid, 2-arachidonoylglycerol (2-AG) which can be further cleaved by downstream enzymes to release arachidonic acid (AA) for cyclooxygenase (COX)-mediated eicosanoid production (PubMed:14610053).  Preferentially hydrolyzes DAGs at the sn-1 position in a calcium-dependent manner and has negligible activity against other lipids including monoacylglycerols and phospholipids (PubMed:14610053).  Plays a key role in the regulation of 2-AG and AA pools utilized by COX1/2 to generate lipid mediators of macrophage and microglia inflammatory responses.  Functions also as a polyunsaturated fatty acids-specific triacylglycerol lipase in macrophages.  Plays an important role to support the metabolic and signaling demands of macrophages (By similarity).
What are the official names of this protein?
Diacylglycerol lipase-beta, DAGL-beta, DGL-beta, KCCR13L, PUFA-specific triacylglycerol lipase, Sn1-specific diacylglycerol lipase beta.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HMUO_CORDI
Sequence: MTTATAGLAVELKQSTAQAHEKAEHSTFMSDLLEGRLGVAEFTRLQEQAWLFYTALEQAADAVRASGFAESLLDPALNRAEVLARDLDKLNDGSEWRSRITASPAVIDYVNRLEEIRDNVDGPALVAHHYVRYLGDLSGGQVIARMMQRHYGVDPEALGFYHFEGIAKLKVYKDEYREKLNNLELSDEQRENLLKEATDAFVFNHQVFADLGKGL
What is the function of this protein?
Allows the bacteria to use the host heme as an iron source.  Involved in the oxidation of heme and subsequent release of iron from the heme moiety.
What are the official names of this protein?
Heme oxygenase.
What is the protein family that this protein belongs to?
Belongs to the heme oxygenase family.
Protein: HIS3_BACC3
Sequence: MKPNFSKGLLPAVVIEEGTKEVLMLAYMNEEAYEKTLKTKRTWFYSRSRRSLWNKGETSGHVQHVQSLYLDCDQDSIVVVVKQVGPACHTGEKTCFHYKII
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDX_TRYBR
Sequence: MSCGDAKLNHPAPHFNEVALMPNGTFKKVDLASYRGKWVVLFFYPLDFTFVCPTEICQFSDRVKEFNDVDCEVIACSMDSEFSHLAWTNVERKKGGLGTMNIPILADKTKSIMKAYGVLKEEDGVAYRGLFIIDPQQNLRQITINDLPVGRNVDETLRLVKAFQFVEKHGEVCPANWKPGSKTMKADPNGSQDYFSSMN
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.
What are the official names of this protein?
Thioredoxin peroxidase, Peroxiredoxin, Thiol-specific antioxidant protein, Thioredoxin-dependent peroxide reductase, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
Protein: RL2_PARXL
Sequence: MAIVKVKPTSPGRRAMVKVVNKDLHKGKPFAPLLDSQSTTAGRNNNGHITTRHKGGGHKHHYRVVDFRRNKDGIAAKVERLEYDPNRSANIALVLYADGERRYIIAPKGVTVGQQLMSGSEAPIRAGNTLPIRNIPVGTTIHCIEMLPGKGAQMARSAGTSAMLLAREGIYAQVRLRSGEIRRVHVECRATIGEVGNEEHSLRQIGKAGANRWRGIRPTVRGVAMNPVDHPHGGGEGKTAAGRDPVSPWGTPTKGYRTRSNKRTTSMIVQRRHKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RR19_GOSBA
Sequence: MARSLKKNPFVANHLLKKIERLNTKAEKEIIITWSRASTIIPTMIGHTIAIHNGKEHLPIYITDRMVGHKLGEFAPTINFRGHAKNDNKSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MDTH_SALPA
Sequence: MSRVSQARNLGKYFLLIDNMLVVLGFFVVFPLISIRFVDQMGWAAVMVGIALGLRQFIQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFATMGIAHEPWLLWFSCFLSGLGGTLFDPPRSALVVKLIRPEQRGRFFSLLMMQDSAGAVIGALLGSWLLQYDFRLVCATGAILFILCALFNAWLLPAWKLSTVRTPVREGMRRVMSDKRFVTYVLTLAGYYMLAVQVMLMLPIMVNDIAGSPAAVKWMYAIEACLSLTLLYPIARWSEKRFRLEHRLMAGLLVMSLSMLPIGMVGNLQQLFTLICAFYIGSVIAEPARETLSASLADARARGSYMGFSRLGLAIGGAIGYIGGGWLFDMGKALAQPELPWMMLGIIGFITFLALGWQFSHKRTPRRMLEPGA
What are the official names of this protein?
Multidrug resistance protein MdtH.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS8_LISMH
Sequence: MKWKKSLTGLSSYKPGKREEEVMAELGLTKITKLSSNENPLGTSPKVAALQANSSVETEIYPDGWASSLRTVVADFYQLDEEELIFTAGVDELIELLTRVLLDTTKNTVMATPTFVQYRQNALIEGAEVREIPLLVDGAHDLDGMLNAIDDNTTIVWVCNPNNPTGNYIDLADIQAFLDKVPSDVLVVLDEAYIEYVTPQPEKHEHLIRTYKNLIITRTFSKIYGLASARVGYGIADKAIIEQLNIVRPPFNTTSIGQKLAIEAIKDQAFIEACRTSNANGIKQYETFAKRFEQVKLYPANGNFVLIDLGIEAGTIFSYLEKNGYITRSGAALGFPTAVRITIGKEEENSAVIALLEKLL
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: ANR31_HUMAN
Sequence: MEEGVQAPDWDSDETVIEGSVTESDLEEKELPWRRLLFDQDASLKSEFSLHPDTRGMCKGMPSPEIQLGFKLREDLQEQMNKNKMMPVLSEDTILQSQDETERNQALLQTRKNCSMFIGSFRQSGLSLNHQNIEGPEAESPEVLPHIEKELSEGRDSPEVSLLSGTAITVSDTVAVKETSLVEPEKILAAPNTFFEPRKEVTMTMTSEETKDEESSLETFVSALESLLTSPESTQEERLFELVSDFDRKELMNPLSDSLSSISIPLNSWSACHRDLLEDAKDDALPAELLEALNTLSEAKVETICHRKEGGSSLIARNECLEVEFNTSQTNEDCTQIAETLQDPNPSGLQTLAHQNITSCEPLSNKRNSNSVTNSSDQETACVLRRSSRLEKLKVSRDAKYSDHMYKMPEKILPKILGCEDLTNNNSSAQNFRMQDPALMIDGKEKNMHSARFKNGKQIRKNEQFSGKKEKMKVNKISLHSINRRNIFGENLVYKAALHDDADLVHHCIKKGGNVNQPSYAGWTALHEASVGGFYRTASELLKGGADVNIKGLYQITPLHDAVMNGHYKVAELLLLNGADPLFRNDDGKCALDEAKDLCMKRLLERYIPKHQKCLTSAQRSSIDPLDIEDVYQHKKPKFSSKSHIWHVYNENSNRQKLEHVKVNKGSKASLFINKEDVYEYYQKDPKNTKFGKSKHKQSTLDQIYSTGLRKGNLHNVKDPNTNVPKGIGRRKTQHKRTQVDDVDCNPRKILAVSPSRRINRLVTYQQHIPETHNDLPEELCEPSSLTLSSLRNGLDSSTEACSVSKEKHIQNLDLSDSQEVQCLELESVDQTEAVSFPGLLLHKEIKLPVVTTDKQPHTLQEQHHVLYKSHENSNLVPKDERFNKWENSFLSFVKENSDNDDDDDCSTSEKAITSKKVLCSTGGKKHYNFKENLTNKKEMGFQQFLLSEDHLSQENELKAVSLTTLPEQEAVNFSYSDNAVISEHVANYEQCIFGPSFDHSNGNPEQNSLACMRTLLTHEASKLTNHVELFKKPQDYIPRAPTFLMNQTDTHIVEKMAKNCDTERNYIDRDQKIIYSNEPLSIVAHSQVIETTKVEKRRQNHLESETIHNIDSHSTDNMSKELANISKLSQREKKEISHKPGMKAGRINKRNARGESQLHLAVRRGNLPLVKALIESGADVNLNDNAGWTPLHEASNEGSIDIIVELLKAGAKVNCENIDGILPLHDAVANNHLKAAEILLQNGANPNQKDQKQKSALDEADDEKMKELLRSYGAIETVNRDESDAIVNEKIPAVRSKRHKQCFCDDGKTIDSSSLSHQERSRESLSVHQTLSAILQDIEEKQEYLLEFEIRNPEDAEQYIEKMLKIKKIMDNVLAKQKAERDDLAKKYRVSIESFKHGALREQLANLAARQKSLLVVAKKQKKISLKIQNCRNVTSLPCLSLRKLPPRSEISSEKDSQELTSLENLEHPQSGSLSPVSGSMQETQLSLETWNYSQNTNICLNSEAVRRGEFSGNDMNSKQNGSDCTLDGFPKSRHSDGTEKNKLPSQPVAFIGQTEYSQKENDLTEATDKDHEFYVSSPVIGKLNISETASVLAENAAHPSNIICDQDLSNYDPKRGNRKTSSQQSPTGASESLAHQGIAVLGSDTVHQMKPYLKKSVSVVPCADDSQISSSSGSGQQDTIKKALNYSTAPKKKCIQIKDLILLGRINPGNNILEFKTQETTHKASILLNGKLKVESGQIYKNPVTWLKDLLGGNSYVTWNYAWSKVTYLGKELLRYVSEDAPILPEPNSVPQQYQPCLPEVACLDDPVQEPNKSMFEKTKFGQGTSRESMQSSPRYLQINEILLISDQEFLPCHIMDQHWKFCVECEELTP
What is the function of this protein?
Required for DNA double-strand breaks (DSBs) formation during meiotic recombination.  Regulates the spatial and temporal patterns of pre-DSB recombinosome assembly and recombination activity by acting as a scaffold that anchors REC114 and other factors to specific genomic locations, thereby regulating DSB formation.  Plays a key role in recombination in the pseudoautosomal regions of sex chromosomes.
What are the official names of this protein?
Ankyrin repeat domain-containing protein 31.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes on chromatin between preleptotene and early pachytene. Associates with the chromosome axes, but disappears from axes upon synaptonemal complex formation.
Protein: LRP_ECOL6
Sequence: MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTPCLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNTAVQKLEEIQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLVIKTR
What is the function of this protein?
Mediates a global response to leucine.  Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons.  For example it is regulator of the branched-chain amino acid transport genes (By similarity).
What are the official names of this protein?
Leucine-responsive regulatory protein.
Protein: DEF74_ARATH
Sequence: MNYKIGIMSLLVITSIIFLFLVPDKVEAQKECIGPCDMFTDCQAACVGIRKGYNYGQCVAWKPKDDDPFTCCCYKLTP
What are the official names of this protein?
Defensin-like protein 74, Low-molecular-weight cysteine-rich protein 43, Protein LCR43.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: LRL2_ARATH
Sequence: MNSSSLLTPSSSPSPHLQSPATFDHDDFLHHIFSSTPWPSSVLDDTPPPTSDCAPVTGFHHHDADSRNQITMIPLSHNHPNDALFNGFSTGSLPFHLPQGSGGQTQTQSQATASATTGGATAQPQTKPKVRARRGQATDPHSIAERLRRERIAERMKSLQELVPNGNKTDKASMLDEIIDYVKFLQLQVKVLSMSRLGGAASASSQISEDAGGSHENTSSSGEAKMTEHQVAKLMEEDMGSAMQYLQGKGLCLMPISLATTISTATCPSRSPFVKDTGVPLSPNLSTTIVANGNGSSLVTVKDAPSVSKP
What is the function of this protein?
Transcription factor that regulates the development of root hairs (PubMed:19675148).  Transcription factor that regulates the development of sperm cells (PubMed:28585562).
What are the official names of this protein?
Transcription factor LRL2, Basic helix-loop-helix protein 69, AtbHLH69, bHLH 69, Protein DEFECTIVE REGION OF POLLEN 2, Protein LJRHL1- LIKE 2, AtLRL2, Transcription factor EN 94, Transcription factor bHLH69, bHLH transcription factor bHLH069.
What are the subcellular locations of this protein?
Nucleus.
Protein: MUTL_ANAPZ
Sequence: MPIVVLSAQTINKIAAGEVIDCPASVVKELVENSIDAGAKTINVHVDKGGRNLISVSDDGCGIACEEMEKAFIGHATSKLIDGDLANVKTMGFRGEGLTAVASVARVKMVSKHVDAERAWSITFEGGEKTRDLTPGVLSCGTHVEVRDLFFATPTRLKFLRTEKAEMQNIVDLLNRLAMINYTIAFSLTIVERQIFKYSAQESLIERLKEMRAFGEVFCEQSLEINHSIDHVRVYGHIGLPTFNKSKPGMVHTFVNGRPIYSTLLLGAVKSAYHGLIPKDRHPVVVLALDVMPAYVDVNVHPSKMEVRFQDKRLVYKAVLDALGEALSSNVYARFSPAATTSEGHDHFAMDSIEKTYGKFFSEDTEAASTMQLQPEVLNHNIPLLFGSSHVDDSKGTHDTRFCADHTHHNDTKGSVHTKSFSARSSSSAESKMEQGCMLEEPPLGYAVCQLFERYIISRAGDYVIIVDQHAAHERLVCEYIKKVTEQEGIKRQVLLMPEFIELGNEYELELLTEYREKLRDLGLIVEPMGDLTVVVREVPAIFGVVDAKALISKILESIMAKGDELFVKGKLSHICGTVACYSSIRSGRIMKLEEMNSLLRHMESTPHSGQCNHGRPTYVKLKLSEIDKLFERT
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: ZW10_DROPS
Sequence: MAARAQIKLLPEMFQSNGCASLEDTKSTVSKVQTRTERFQERVRKHIDENYSEFMTNHTSPDIFLEESSSLGREINDLLETVGTEGLAALNGSSTQLADHSRELRELMLGLQVSEHILKIDELFQCVEEAKGTKDYLVVLDLVGRLRSLIYGEGEAATQDVVRIFQALECYETIKVKYHVQAHLLQQNMQERFDRLVQLNCKSFPNSKCVTLLVSKEEGQLHDIVIALFQERYNPVRLCEFLLENCIEPLILKPVGVECNENAEAGTYVQLSLSYSTKESGTASGTSTQLRPNYKQVLEHFRLLLQTLSGINHSLSSSQHVFSIIGDHVKDRMMHLLVNDCLIPAVPETMEEYQASTLCEDVAHFEQYLADSFLINPEVDRGLSQFIEQYGTYYRNRLCSRVLESTREIIQRDLQDMVLVAPNNQAMDVTGCDPFLFPRCMVSRSAQDFMKLMERILRQPTEKPGEDEADPLAGVIGMMLQTYIDEVPKVHKKLLESIPQQSVLFHNNCMYFTHWVAQNANKGIESFPALVKTLQATGTMHFRVQVTYQTSILMDIMESFEFESPHTLGTGPLKLVRQCLRQLELLKNVWQNVLPDNVYNSTFVELLHAFINELVRHIFTQRDISATMASDLSDLIDVVLEKAPKLFRDPHEVHQVRSWMKLQQLKTMMNASLKEITELWCKGAGPLTANYKADEIRYLIRALFQDTDRRAKAITQIM
What is the function of this protein?
Required for accurate chromosome segregation.
What are the official names of this protein?
Centromere/kinetochore protein zw10, Mitotic 15 protein.
What is the protein family that this protein belongs to?
Belongs to the ZW10 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome, centromere, kinetochore. Note=Excluded from the nucleus during interphase but migrates into the nuclear zone during prometaphase. At metaphase, found in a filamentous structure that may be specifically associated with kinetochore microtubules. At anaphase, found at or near kinetochores of separating chromosomes. At the beginning of telophase, becomes excluded again from the nucleus and is dispersed in the cytoplasm (By similarity).
Protein: VL2_HPVME
Sequence: MVSHRAARRKRASATELYKTCKQSGTCPPDVINKVEGTTLADKLLQWTSLGIFLGGLGIGTGSGTGGRTGYIPLGGKPNTVVDVSPARPPVVIEPVGPTEPSIVQLVEDSSVITSGTPVPTFTGTSGFEITSSSTTTPAVLDITPSSGSVQVSSTSFTNPAFADPTIIEVPQTGEVSGNVFVSTPTSGTHGYEEIPMQVFATHGTGTEPISSTPIPGVSRVAGPRLYSRAHQQVRVSNFDFVTHPSSFVTFDNPAFEPVDTTLTYEPADIAPDPDFLDIVRLHRPALTSRRGTVRFSRVGKKATMFTRRGTQIGAQVHYYHDISGIAPADSIELQPLVAPEQSDPMDTLYDIYAPDTDNTTVLDTAFHNATFTSRSHISVPSLASTASTTYANTTIPIGTAWNTPVNTGPDVVLPATSPQLPLTPSTPIDTTYAITIYGTNYYLLPLLFFLLKKRKRLPYFFADGIVAL
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: TRBP2_TETNG
Sequence: MNDETASDSWKRNSGCSSIEQMLAVNPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVAVGEINCTGQGPSKKAAKHKAAEAALKMLKGGLGAPAGFSVGVDGFVEVDVSTDGDSSQSEMKTSGNSQQTECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLSRIHDVPVDLRTSNDADPEEDTFNMHMGSRTESGKSKSFSCTWDSLRNSAGEKILQLRSHPLGIPTDSNFCSLLSDLSLEQRFDVSYLDLEERSLSGLCQCLVELSTQPITVCHGCASSTDAARASAAHNALQYLKIMAGGK
What is the function of this protein?
Required for formation of the RNA induced silencing complex (RISC).  Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of dicer1, ago2 and tarbp2.  Within the RLC/miRLC, dicer1 and tarbp2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto ago2.  ago2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from dicer1 and tarbp2.  May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by dicer1.
What are the official names of this protein?
RISC-loading complex subunit tarbp2.
What is the protein family that this protein belongs to?
Belongs to the TARBP2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_THET2
Sequence: MAKIGFVSLGCPKALVDSEQILSRLKALGYETSPSYEEAELVIVNTCGFINEAVEESLEAIGEALKENGKVVVTGCLGARPEKIRERHPQVLAVTGPGEVERVLEAVQEVLPAPRDPFLDLIPPQVKLTPRHYAYVKLSEGCDHRCSFCIIPKLRGRLRSRDAADVLAEAARLVATGTKELLLVAQDLSAYGVDLGHRESLWGDRPVRAELKDLLTHMAELGVWIRLHYVYPYPHVKDLLPLMAEGKVLPYLDVPLQHASPRILRLMRRPGGYESHLKTLKAWREVVPELALRSTFIVGFPGETEEDFQILLDFLEEAELDRVGVFAYSPVEGAEANRLPDPVPEEVKEERKARLLEVQARVSLRKNQRFVGKTLEVLVDELPEPGLAVGRTYRDAPGVDGVVYVETDGTVRVGERIPVRILRADTYDLHGVQA
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APGM_THEM4
Sequence: MIDRQQILNELISPNSSKIVLLVMDGIGDIPGEDGLTPLQKANTPKLDELAKQSDLGQTIPVLPGITPGSGPGHLGIFGYDPLKYQIGRGILEALGIDVEVGEKDLVARGNFATLEGDIIVDRRAGRPSSEESAKVVEILNENIHKIEDVEVKFYPGKEHRFVVKLTGEGLYDKLEDADPQKEGKPIKYTKALDESSKKSEKIINILIDRIKEVLKDQQKMNFALLRGFSKYPNLPSFGDVYKLRPAAIAVYPMYKGLAKLVGMEILKTGQTIEDEFKTVKENWEKYDFFYVHVKKTDSYGEDGNFESKVKVIEEVDKNLGLLLELKPDVLIVTGDHSTPCAMKGHSFHPVPLMIYSKFTRKGLSKLYNEFECARGTLGTIPAVDVMSLALAYAGRLEKYGA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
Probable 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, aPGAM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
Protein: HSLV_PHOPR
Sequence: MTTIVSVRRNGKVVIAGDGQVSLGNTVMKGNARKVRRLYNNKVLAGFAGGTADAFTLFERFERKLEMHQGHLLKSAVELAKDWRTDRALRKLEAILAVADETGSLIITGNGDVVQPENDLIAIGSGGNFAQAAATALLENTDLGAREIAEKSLNIAGDICVFTNHNHTIEELETK
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_FRATF
Sequence: MAHKKAGGSTRNGRDSNPKYLGVKRYGGELVKAGTIIIRQRGTKTHPGVNVGCGKDHTLFALKDGTVKFHTGGALNRKFVSIEE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: GR98C_DROME
Sequence: MEMEAKRSRLLTTARPYLQVLSLFGLTPPAEFFTRTLRKRRRFCWMAGYSLYLIAILLMVFYEFHANIVSLHLEIYKFHVEDFSKVMGRTQKFLIVAIATCNQLNILLNYGRLGLIYDEIANLDLGIDKSSKNFCGKSHWWSFRLRLTLSIGLWMVIIIGVIPRLTLGRAGPFFHWVNQVLTQIILIMLQLKGPEYCLFVLLVYELILRTRHVLEQLKDDLEDFDCGARIQELCVTLKQNQLLIGRIWRLVDEIGAYFRWSMTLLFLYNGLTILHVVNWAIIRSIDPNDCCQLNRLGSITFLSFNLLLTCFFSECCVKTYNSISYILHQIGCLPTAEEFQMLKMGLKEYILQMQHLKLLFTCGGLFDINIKLFGGMLVTLCGYVIIIVQFKIQDFALIGYRQNTSDTS
What is the function of this protein?
Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
What are the official names of this protein?
Putative gustatory receptor 98c.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr2a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TOP2_ASFM2
Sequence: MEAFEISDFKEHAKKKSMWAGALNKVTISGLMGVFTEDEDLMALPIHRDHCPALLKIFDELIVNATDHERACHSKTKKVTYIKISFDKGVFACENDGPGIPIAKHEQASLIAKRDVYVPEVASCHFLAGTNINKAKDCIKGGTNGVGLKLAMVHSQWAILTTADGAQKYVQHINQRLDIIEPPTITPSREMFTRIELMPVYQELGYAQPLSETEQADLSAWIYLRACQCAAYVGKGTTIYYNDKPCNTGSVMALAKMYTLLSAPNSTIHTTAIKADAKPYSLHPLQVAAVVSPKFKKFEHVSIINGVNCVKGEHVTFLKKTINEMVVKKFQQTIKDKNRKTTLRDSCSNIFVVIVGSIPGIEWTGQRKDELSIAENVFKTHYSIPSSFLTNMTRSIVDILLQSISKKDNHKQVDVDKYTRANAGGKKAQDCMLLAAEGDSALSLVRAGLTLGKSNPSGPSFDFCGMISLGGVIMNACKKVTNITTDSGETIMVRNEQLTNNKVLQGIVQVLGLDFNCHYKTQEERAKLRYGCIVACVDQDLDGCGKILGLLLAYFHLFWPQLIIHGFVKRLLTPLIRVYEKGKTVPVEFYYEQEFDAWAKKQTSLANHTVKYYKGLAAHDTHEVKSMFKHFDNMVYTFTLDDSAKELFHIYFGGESELRKRELCTGVVPLTETQTQSIHSDRQIPCSLHLQVDTKAYKLDAIERQIPNFLDGMTRARRKILAGGLKCFASNNRERKVFQFGGYVADHMFYHHGDMSLNTSIIKAAQYYPGSSHLYPVFIGIGSFGSRHLGGKDAGSPRYISVQLASEFIKTMFPAEDSWLLPYVFEDGQRAEPEYYVPVLPLAIMEYGANPSEGWKYTTWARQLEDILALVRAYVDKNNPKHELLHYAIERKITVLPLRPSNYNFKGHLKRFGQYYYSYGTYVVSEQRNIITITELPLRVPTVAYIESIKKSSNRMAFIEEIIDYSSSETIEILVKLKPNSLNRIVEEFKETEEQDSIENFLRLRNCLHSHLNFVKPKGGIIEFNSYYEILYAWLPYRRDVYQKRLMRERAVLKLRIIMETAIVRYINESADLNLSHYEDEKEASRILSEHGFPPLNQSLITSPEFASIEELNQKALQGCYTYILSLQARELLIAAKTRRVEKIKKMQARLDKVEQLLQESPFPGASVWLEEIDAVEKAIIKGRSTQWKFH
What is the function of this protein?
Type II topoisomerase.  Processively relaxes supercoiled DNA.  Displays DNA-supercoiling activity only when associated with the viral histone-like protein.
What are the official names of this protein?
DNA topoisomerase 2, DNA topoisomerase II.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Localizes to the cytoplasmic viral factories.
Protein: MRAZ_BURL3
Sequence: MFQGASALTLDAKGRMSVPARYREALQGQAEGRVTVTKHPDGCLLLFPRPEWEVFRAKIAALPMDAHWWRRIFLGNAMDVDLDSAGRILVSPELRMAAGLEKEVMLLGMGSHFELWDSQTYNAKEQAAMAQGMPDALKNFTF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CBIC_METJA
Sequence: MGAISKDGLNIANKSREIVRNKIKEVLGDRINEFNEKEMGIIERVVHATADPEYAKLLVFKNNPIEEGIKAIKEEKPIIVDVNMIKAGIRYNKVHCFINHPDVYEVAKKEGITRAVASMRLAKDLIDDGIVVIGNSPTALFEVIRLVKEENIKPKLIVGVPVGFVQASESKEALREVNVPSISTIGPKGGTPVAVAIINGIIAYAKNEKA
What is the function of this protein?
Catalyzes the conversion of cobalt-precorrin-8 to cobyrinate.
What are the official names of this protein?
Cobalt-precorrin-8 methylmutase, Cobalt-precorrin isomerase.
What is the protein family that this protein belongs to?
Belongs to the CobH/CbiC family.