PharMolix/UniProtQA huggingface dataset:
Protein: AZIN2_XENLA
Sequence: MQGYIQESDFNLVEEGFLARDLMEEIINEVSQTEDRDAFFVADLGDVVRKHLRFLKALPRVKPFYAVKCNSSKGVVKILAELGAGFDCASKTEIELVQDVGVAPERIIYANPCKQISQIKYAAKNGVQMMTFDNEVELSKVSRSHPNARMVLRIATDDSKSSARLSVKFGAPLKSCRRLLEMAKNLSVDVIGVSFHVGSGCTDSKAYTQAISDARLVFEMASEFGYKMWLLDIGGGFPGTEDSKIRFEEIAGVINPALDMYFPESSDVQIIAEPGRYYVASAFSLAVNVIAKKEVEHSVSDDEENESSKSIMYYVNDGVYGSFNCLVFDHAHPKPILHKKPSPDQPLYTSSLWGPTCDGLDQIAERVQLPELHVGDWLLFENMGAYTIAASSNFNGFQQSPVHYAMPRAAWKAVQLLQRGLQQTEEKENVCTPMSCGWEISDSLCFTRTFAATSII
What is the function of this protein?
Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake.  AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizyme (AZ) on ODC activity by competing with ODC for antizyme-binding.  Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production.  Participates in the morphological integrity of the trans-Golgi network (TGN) and functions as a regulator of intracellular secretory vesicle trafficking.
What are the official names of this protein?
Antizyme inhibitor 2, AzI2, Ornithine decarboxylase 2, ODC 2, xODC2, Ornithine decarboxylase-like protein, ODC-like protein, ornithine decarboxylase paralog, ODC-p.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. ODC antizyme inhibitor subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Membrane. Cytoplasmic vesicle. Endoplasmic reticulum-Golgi intermediate compartment. Golgi apparatus, cis-Golgi network. Golgi apparatus, trans- Golgi network. Cytoplasmic granule. Cell projection, axon. Cell projection, dendrite. Perikaryon.
Protein: YABD_BACSU
Sequence: MLFDTHAHLNAEQYDTDLEEVIERAKAEKVERIVVVGFDRPTITRAMEMIEEYDFIYAAIGWHPVDAIDMTEEDLAWIKELSAHEKVVAIGEMGLDYHWDKSPKDIQKEVFRNQIALAKEVNLPIIIHNRDATEDVVTILKEEGAEAVGGIMHCFTGSAEVARECMKMNFYLSFGGPVTFKNAKKPKEVVKEIPNDRLLIETDCPFLTPHPFRGKRNEPSYVKYVAEQIAELKEMTFEEIASITTENAKRLFRIN
What are the official names of this protein?
Uncharacterized metal-dependent hydrolase YabD.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.
Protein: PR23C_HUMAN
Sequence: MGSRPCSPSACLAPWWGQQPGGPGPAKRSRLEEPAGPESRAAPSPEDPAGTPAVDALTSMVVLDAGCALRVPLEDVDLVLELAPMSVLRVSLGGHTLIVIPEVLLSSVDECSGAQGDWSAGLEVDVFLGAHGEDVVVEQEVCASVPEIAAEEEAYEEDADSEFPELWMDSAAGSAAGLYPSARSMFSPYREGPIRGPCALAPNPSSERRSPRPIFDLEFHLLEPVPSSPLQPLPPSPSPGPHARPELPERPPCKVRRRLFQE
What are the official names of this protein?
Proline-rich protein 23C.
What is the protein family that this protein belongs to?
Belongs to the PRR23 family.
Protein: RPOB_EMIHU
Sequence: MLDRNKNIYKYLLPNLLDVQRASYCWFLEKGFVQELRTFSVIRDYLGDLELNFATKFYTINPPRYTLEEAKRKDATYSVRIFIRAQLNYLEGADPQEKQVFLGDIPLMTDSGTFLVNGIERIIINQIVRSPGIYYKSEADKQGVRIYTASLISNRGTWVKFEIDKDDLVYIKIDKAKKFSIFVFLKALGLDNQEIFNSIENINYFRKTSNTDEQLTTEQCLLEVHSHLKPEEPATAKGCQKLLYAKFFDSKKYDLGYVGRHKLNQALMLDIDSDVRILTSLDLIGIINQLIRFRFMPIVSDDIDHLGNRRIRSVGELMANQIRIGLNRLERVVRERMAICEHSYLRVNTLVNPKPLAASIREFFGSNPLSQFMDQTNPLAELTHKRRISVLGPGGIARDRAGFVVRDIHPSQYGRICPVETPEGPNAGLIGSLSTYGKINAYGFIETPFYKVKQGKVLKDLPPIYLDAIAEEQYKLAAGDVATDEHGVLKQPDVPVRYQQNIVTVSKNEVDYIAVSPIQVVSLATSLIPFLEHDDANRALMGSNMQRQSVPLLYADAPLVGTGLESQTARDSGMAILSSNCGKVVTLSDEQIVVQDKNGNQLIYNLTKYKRSNQDTCINQKPCVSLYEKVRVGQLLADGTSTETGELAVGQNILIAYMPWEGYNYEDAFVVNERLLYDDLHTSIHIEKFEIESRQTKLGAEEITRDLPNVNEKSLSKLDENGIIHIGSWVEPGDILVGKLTPKGESDYLPEGKLLRAIFGEKSRDVRNTSLKLHHGVNGRVLDVKIFSRANQDDLSPGTNEVIKVYIAQIRKIQIGDKVAGRHGNKGIISKILPRQDMPYLPDGTPVDILLNPLGVPSRMNVGQIFECLLGLAAEHLNARFKVIPFDEMNGVEASRGFVNNTLMEAAEKQPWVFSTQHPGKMMLTDGQTGEMFDNPITVGRAYVLKLVHLVDDKIHARSTGPYSLVTQQPLGGRAQQGGQRLGEMEVWALEAFGAAYTLQELLTIKSDDMQGRNETLNAIVKGYPIPRPGTPESFKVLLRELQALCLDIAAYKIEDTTLLTEDKEINLMSELNSSRDDQSVANNYLLTRGTTP
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IGSF2_MOUSE
Sequence: MACILCVASLFLSLTKFSIGQREVKIQEGPLYRAEGYPVSIRCTVSGHQGPSTQDFRWSIYLPSAPTKEVQIISTKDAGFSYAVYAQRVQSKEIYIERLQGDSVLLHISKLQMKDAGEYECHTPNTDGKYFGSYSAKTNLTVVPDTLSATMPSQTLSKKEGEPLELTCETTKATVQHTHLSLTWYLMQEGGGSQATEIVSLSKDFVLTPGSSYADRFVAGDVRLDKLGATSFRLSVGKLQPSDQGQVFCEATEWIQDPDETWTLITRKQTDQTALRIQPAARDFTVSITASSSPDEGKPLELVCLAVGRDGNPQLQGVWFLNGKEIAQTDAGGVLDLKRDYRDRASQGQLQVSKLSAQTFSLKIFSVGPEDVGTYSCEVAEVARTQMGSWQVLQRKQSPGYRVQLREPAARSVTVSAEQRTVWEGETLTLLCKAAGDVSALSVSWWLTPQDQSTPVFVAGMGQDGTVQLGVSSPGPAHRGNRRLEKVDWATFRLEIASAMVTDSGTYECRVSERLQNQAKGLQSTQKISVTVKSLKSSLRVNLMSRQPQVMLAHTFHLSCVVRANYSDLKLPFSVTWQFQPAGSGAFHRLIRIAHNGTVEWGDVLSQIHRKTKVSQSFFRSQLQIYDAAMEETGVYRCTVEVYDRDSICTSGPARVSATSNLLMITVTFPESKLSVNSSSQVQELSISSSTQIECAILSRSAGNLPLSIIWYFSSVSANASYLKILEMDQSSVVKYGDEFQTPRSKQKFYSEKVSQDLFLLNILSVEDSDQGHYHCAVEEWLLSTNDTWQKLERKTSGLTELKLRPTGSQVHVSKVNWTGNATEYGEAGFSCSLDGSGSTASLYSVTWYRGRGTATATAAAVANATATITAPAGSQMLVHLQYDGLLQYGREGSRRLQHCYRSSPTDFVLKLHRVEMEDAGIYWCRVTEWQQHGHPGKWINQASGESQRMVLRVLRSEPTVSSLICSSGPLLHFLIVCPFVMLLLLATSFLCLYRKARKLSQLSLSAKKEKALWVGMRKTSLQKEAGEESGHY
What is the function of this protein?
Plays a role as inhibitor of T-cells proliferation induced by CD3.  Inhibits expression of IL2RA on activated T-cells and secretion of IL2.  Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation.  Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium.  Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus.  Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells (By similarity).
What are the official names of this protein?
Immunoglobulin superfamily member 2, IgSF2, Glu-Trp-Ile EWI motif-containing protein 101, EWI-101.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: EFTS_RICTY
Sequence: MSEINISAAAVKELREKTGAGMMDCKKALIETSGNFEEAIDFLRKKGLAAAVKKFGRIASEGLTAIKINGLTSVVIEVNSETDFVARNEQFQNLVKDIVNLAIIAQNIDALKISKMQSGKSVEEEIIENIATIGENLTLRRMDILEISNGAIGSYVHNEVVPHLGKISVLVGLESNAKDKAKLAALAKQIAVHVAGNNPQSIDTLSLDQALVERERKVFFEKSKEEGKPDHIIEKMVEGRIRKFFSEVVLLQQNFLFEPKLTVAEVIKNAEQELGAEIKITKFIRYALGEGIEHEEKNFADEVASITKC
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSRP_SHIBS
Sequence: MDNAVDRHVFYISDGTAITAEVLGHAVMSQFPVTISSITLPFVENESRARAVKDQIDAIYHQTGVRPLVFYSIVLPEIRAIILQSEGFCQDIVQALVAPLQQEMKLDPTPIAHRTHGLNPNNLNKYDARIAAIDYTLAHDDGISLRNLDQAQVILLGVSRCGKTPTSLYLAMQFGIRTANYPFIADDMDNLVLPASLKPLQHKLFGLTIDPERLAAIREERRENSRYASLRQCRMEVAEVEALYRKNQIPWINSTNYSVEEIATKILDIMGLSRRMY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: GCH1_STRPN
Sequence: MDTQKIEAAVKMIIEAVGEDANREGLQETPARVARMYQEIFSGLGQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKLARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATLTTVARGLFETDKDLRDQAYRLMGL
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: DNAK_CHLPD
Sequence: MGKIIGIDLGTTNSCVAVMQGTQPTVIENSEGNRTTPSMVAFTKSGDRLVGQAAKRQAITNPKNTIYSIKRFVGRKFDEVPNEKKLAPYDIVNEGGEARVKINDKAYSPQEISAMILQKMKQTAEDFLGEKVSEAVITVPAYFNDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGLDKKQSSEKVAVFDLGGGTFDISILELGDGVFEVKSTDGDTHLGGDDFDQKIINFLADEFKKQEGIDLRNDAIALQRLKEAAEKAKVELSSRTDTEINLPFITATQEGPKHLVINLTRAKFEAMCSDLFDKILEPCHRAVKNSSVEIKDIDEVVLVGGSTRIPKVQALVKEFFGREPNKSVNPDEVVAVGAAIQGGVLKGDVTDVLLLDVSPLSLGIETLGGVMTRLIEANTTIPTRKQEVFSTAGDNQTSVEVHVLQGERPMASDNKTLGRFHLGDIPPAPRGLPQIEVTFDIDSNGILSVSAKDKATGKEQSIKIEASGKLSDAEIEKMKRDAKEHAAEDMKKKEEIDSKNAADGLIFSTEKQLAELGDKIPSDKRPALEGALEKLKDATKNGTTESIKNAMDELSKVWNDVSSNLYQAPGAETNASEPTQNTDGSGHTKKSGNDGEVENAEFEVIDGNGK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RPB11_PLACH
Sequence: MSVPTLSNKPENVDLLVLPHGEEKVKCQISDKGDCNIFTIKLEDHTIGNLIKQSLCQDPKVTFAAYRQPHPLQNAIEITIRPKGYAGVKLLSDNVHSILNQVSTLRETFANRVQKYKEKNAYHGNR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  It is composed of mobile elements that move relative to each other.  RPB11 is part of the core element with the central large cleft (By similarity).
What are the official names of this protein?
Probable DNA-directed RNA polymerase II subunit RPB11, RNA polymerase II subunit B11, DNA-directed RNA polymerase II subunit J.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NOB1_PYRAB
Sequence: MLLKLKLVLDSSVFIQGLDIEGYTTPKVVDEVKDRESRILLESLISSGKVKVVEPSKEALRAVKNAALKTGEIEELSEADLEVLALAYELKAEVFSDDYNVQNVARILGLKFRTLKRGIKKVIKWQYVCIGCGRKFKEMPPGGICPDCGSPVKLIPRRQRS
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Processes pre-16S-rRNA at its 3' end (the D-site) to yield the mature 3' end (By similarity).
What are the official names of this protein?
Endoribonuclease Nob1, RNase Nob1, Endonuclease VapC14, Putative toxin VapC14.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: KBAY_ECO81
Sequence: MSIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSPVILAGTPGTFKHIALEEIYALCSAYSTTYNMPLALHLDHHESLDDIRRKVHAGVRSAMIDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDDMSVDAESAFLTDPQEAKRFVELTGVDSLAVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFVRRTIELGVTKVNVATELKIAFAGAVKAWFAENPQGNDPRYYMRVGMDAMKEVVRNKINVCGSANRISA
What is the function of this protein?
Catalytic subunit of the tagatose-1,6-bisphosphate aldolase KbaYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP).  Requires KbaZ subunit for full activity and stability.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit KbaY, TBPA, TagBP aldolase, D-tagatose-bisphosphate aldolase class II, Ketose 1,6-bisphosphate aldolase class II, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase KbaY subfamily.
Protein: Y1434_DICT6
Sequence: MKALYFDCFSGISGDMILGALIDLGIDVEKWKTELNKIPVKGYKIEISKKQKNSIWGTDVNIIIDDHHSHRHLEDLLKIVDESGLSENIKTKAKNIFYKIAEAEAKIHNQPIDEVHFHEIGALDTIIDVLGSLILLEMLEVEEIYSSPLPLGSGFVNTAHGTIPVPAPATLEILRGIPVYKDGREGELVTPTGAAIISTVANFVQELPPIRVDKIGYGCGKKDFSFPNLLRVYVGELVESTVKERNIVLETNIDDMNPQIFGYLVEKLFKEGALDVFLTPVYMKKGRPGILLSVIAPLVMEERLSEVIFRETTTLGIRKIYVDKKIMPREIKEIETKWGKVRIKVANINGIRKAYPEYEDCKSIAERENIPLKDVILEIEKLMERE
What are the official names of this protein?
Putative nickel insertion protein.
What is the protein family that this protein belongs to?
Belongs to the LarC family.
Protein: PLSY_PELUB
Sequence: MEYLIVALSSYLLGSIPFGFILTKIFLKKDIRDIGSGNIGATNALRTGNKTLGYATLLLDITKAVLPVLYVKFNYPDYIFIASLSAFLGHVFPIWLKFKGGKGVATYVGILFSINIFLGLVFIISWAVTFLISKYSSLSSLVGSLMVPMYLIVFENYNSIFFIIMFVLIFYTHRENVKRLKNKEETKTKIY
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TVP15_ASHGO
Sequence: MSENDQKGVKFIRALLVTTGAVATLGFLVQLSEVASEFLAAARACFGLPLSVLLVYLEFRPVPLLQQYASFYYSYMGRALLQLLLAVMLLPAGFFQVCAFTMLFMTGFICAALELSSSAPELPSFRNDGRALSIGAEEDDDMI
What is the function of this protein?
Golgi membrane protein involved in vesicular trafficking.
What are the official names of this protein?
Golgi apparatus membrane protein TVP15.
What is the protein family that this protein belongs to?
Belongs to the TVP15 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: RSMH_ALCBS
Sequence: MTTEDTQYAHQPVMLEEVLDMWFSQSEGFYVDGTFGRGGHSRALLSRLGENGRLIGIDRDPQAIAAGQQLAASDSRFHMMAGRFDCLPQAVEQAGRPIDGLLLDLGVSSPQLDDAARGFSFLRDGPLDMRMDPTQGESVAEWLSYAAEKDIANVLYRYGEERKSRWIAKRICETRKEQPITRTLQLADLIESVLGRNEQGKHPATRSFQALRIHINGELDALDQVLEQSLETLAIGGRLAIISFHSLEDRIVKLFIRDHSGRAPKGRGGLPLGDELPQRLEPVGKVMRASKAELKVNVRSRSAVLRIAEKVA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THO1_YEAST
Sequence: MADYSSLTVVQLKDLLTKRNLSVGGLKNELVQRLIKDDEESKGESEVSPQEQNQEQGSEPAAIEEPASQNITEKKEVSSEPKETNEPKEENKDVQKPSDGPSATASENEQAAASTAAPALSPEEIKAKALDLLNKKLHRANKFGQDQADIDSLQRQINRVEKFGVDLNSKLAEELGLVSRKNEPESGNNGKFKNRNKNANNRSRVSKNRRGNRSGYRR
What is the function of this protein?
Unknown; suppressor of the transcriptional defect of HPR1 by overexpression.
What are the official names of this protein?
Protein THO1.
Protein: RRF_BACCR
Sequence: MGQQVLKSSNEKMEKAVAAYSRELATVRAGRANASVLDKVQVDYYGAPTPVVQLANITVPEARLLVIQPYDKTSIGDIEKAILKADLGLNPSNDGTVIRIAFPALTEERRRDLVKVVKKYAEEAKVAVRNVRRDGNDDLKKLEKAGEITEDDLRGYTEDIQKETDKYIAKVDEIAKNKEKEIMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COXX_GEOKA
Sequence: MAELKAVHQDAADAGHRSHVSVKAVWRELSSVVKIGIVNSNLITTFAGMWLAFYFTGEHFLENLHLVFFTLFGAALVIAGSCAINNYIDRDIDQYMERTKARPTVTGTMDPRRVLWLGIGLVAIGEMGLLMTTVTAAVVGLIGMATYVFLYTLWTKRHYTINTVVGSISGAVPPVIGWTAVDPEFHIVPLILFLIMFLWQPPHFLALAMKRCEEYRAAGIPMLPVVHGFAMTKRQIIVWVACLLPLPFYLFSLGVPFLIVATLLNVGWLLLGLAGLKMKDDIKWAKWMFVYSLNYLTILFVAMIIATLW
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNH2_DELAS
Sequence: MRSRKSLPPLPPEQACLPWHPPGLVAGVDEAGRGPLAGPVVAAAVILDDLNPIEGLNDSKKLTAARREALYDEIRAKALCCSIAEASVEEIDRLNILQATLLAMRRAVLGLRLKPVLVLVDGNQLPVLDVQAEAIVKGDSLVQAISAASILAKVTRDRWCERLHEQYPEYGFDGHKGYGTAAHLAALRLHGACEEHRRTFAPVAHVVSIARMAEPLAAARVAAAAQGAQALLLSA
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_HYPNA
Sequence: MRCPFCGSDNTSVKDSRAAEDDTAVRRRRVCESCGARFTTFERVQLREIIVVKRDGKRSLFDREKLQRSILIALRKRPVDRDRIDQMVSGIVRKLESGGETEVPSSEVGELVMEALKRVDPVGYVRYASVYRDFKDPSDFAQFIEKAALEDEDDDADGK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: SYC_STAES
Sequence: MITLYNTLTRRKETFEPIEPGKVKMYVCGPTVYNYIHIGNARPAINYDVVRRYFEYKGYEVIYVSNFTDVDDKLINRSKELNESVPEIAEKYIKAFYEDVGALNVKKATSNPRVMHHMGEIIDFIKELVDEGYAYESDGDVYFRTRQFDGYGKLSHQSLDDLKVGARIEAGEQKEDALDFTLWKKAKPGEISWNSPFGKGRPGWHIECSVMAYHELGSTIDIHAGGSDLQFPHHENEIAQSEAHNHAPFANYWMHNGFINIDNEKMSKSLGNFILVHDIIKEVDPDVLRFFMISVHYRSPINYNLELVGAARSGLERIRNSYKLIEEREQIASDLEEQSEYIQQIDKILNQFETVMDDDFNTANAVTAWYDLAKLANKYVLENTTSTKVLNRFKEVYSIFSDVLGVPLKSKETEELLDEDIEQLIEERNEARKNKDFARADEIRDMLKARHIILEDTPQGVRFKRG
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIMG_MYCTU
Sequence: MSAWRAPEVGSRLGRRVLWCLLWLLAGVALGYVAWRLFGHTPYRIDIDIYQMGARAWLDGRPLYGGGVLFHTPIGLNLPFTYPPLAAVLFSPFAWLQMPAASVAITVLTLVLLIASTAIVLTGLDAWPTSRLVPAPARLRRLWLAVLIVAPATIWLEPISSNFAFGQINVVLMTLVIVDCFPRRTPWPRGLMLGLGIALKLTPAVFLLYFLLRRDGRAALTALASFAVATLLGFVLAWRDSWEYWTHTLHHTDRIGAAALNTDQNIAGALARLTIGDDERFALWVAGSLLVLAATIWAMRRVLRAGEPTLAVICVALFGLVVSPVSWSHHWVWMLPAVLVIGLLGWRRRNVALAMLSLAGVVLMRWTPIDLLPQHRETTAVWWRQLAGMSYVWWALAVIVVAGLTVTARMTPQRSLTRGLTPAPTAS
What is the function of this protein?
Responsible for the addition of alpha-(1-2) mannose branches to the linear mannan core on the biosynthetic pathway to mature lipoarabinomannan (LAM).
What are the official names of this protein?
Polyprenol-phosphate-mannose-dependent alpha-(1-2)-phosphatidylinositol mannoside mannosyltransferase, Alpha-D-mannose-alpha-(1-2)-mannosyltransferase, Alpha-mannosyltransferase, Alpha-ManT, PPM-dependent mannosyltransferase, Polyprenol-phosphate-mannose alpha-mannosyltransferase, PPM alpha-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 87 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DUSB_VIBCH
Sequence: MKIGNYQLKNNLIVAPMAGVTDRPFRELCLRYGAGMAVSEMMSCNPALWKTAKSQNRMVHEGESGIRSVQIAGSDPQLMAEAAQFSVENGAQIIDINMGCPAKKVNKKLAGSALLRYPDVIEDILKAVVNAVNVPVTLKTRTGWDTDNKNCLSIAQLAEDCGIQALALHGRTRACMYKGEAEYDSIKAVKAAVSIPVIANGDIDSPEKARYVLEYTGADALMIGRPAQGRPWIFQEIQHFLEHGTTMPELPISEVKDIMLGHVTALHQFYGEYLGPRIARKHVSWYLQEHEQASAFRRTFNAIETADQQLDALEGYFDNVAS
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.
What are the official names of this protein?
tRNA-dihydrouridine synthase B.
What is the protein family that this protein belongs to?
Belongs to the Dus family. DusB subfamily.
Protein: AAR3_ARATH
Sequence: MDSSPVSARFDIFEIYRRFCAIRSGQQLCNKKPCDGEESQRFNLSKEAITQLLYLVENKFQARNSIFDELFKLMSRLDLMVDFTEFTCFYDFVFFMCRENGQKNITISRAITAWKLVLAGRFRLLNRWCDFIEKNQRHNISEDTWQQVLAFSRCVHENLEGYDSEGAWPVLIDDFVEHMYSILGPNKDTSLFCKCGDTESESCLYQEDEHHKDYRRPHTGLRNIPGLKRKTSKKNDEEEEDEDEEVLETQNSSSLLNFKRIKTSNSPRCSSKSPCSIERSLSQGFASLLSTGDKP
What is the function of this protein?
May contribute to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes; neddylation of cullins play an essential role in the regulation of SCF-type complexes activity (By similarity).  Regulates responses to the synthetic auxin 2,4-dichlorophenoxyacetic acid (2,4-D) in roots, probably by modulating the SCF(TIR1) ubiquitin E3 ligase complex-mediated proteolysis (PubMed:17905859).
What are the official names of this protein?
Defective in cullin neddylation protein AAR3, Protein ANTIAUXIN-RESISTANT 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y2682_VIBC3
Sequence: MIIYLHGFDSNSPGNHEKVLQLQFIDSDVRFINYSTLHPKHDMQHLLKEVHKAIEQSGDPNPLICGVGLGGYWSERIGFLCGIKQVIFNPNLHPELTMQGRIDRPEEYEDISTKCVEKFRAKNQGRCLVILSRQDEIHDNQKTAQELQDYYDIVWDDTQTHKFKKISHHLQAMKAFKAA
What are the official names of this protein?
UPF0227 protein VC0395_A1482/VC395_2007.
What is the protein family that this protein belongs to?
Belongs to the UPF0227 family.
Protein: PSB_METVS
Sequence: MISGSEYHKEYMKGTTTVGLICEDGVVLATDKRATMGNLIADKEAKKLYKIDDYIAMTIAGSVGDAQSLIRLLSAEAKIYKMRTGNNMTPLSCTTLTSNVLHGNRHYPLLTQLIIGGYDLINGPKLFSLDPVGGINEESSFTATGSGSPTAYGVLEAEYKSEINIEKGLLIAVKALISAMQRDAYSGNGISLAKIDKTGVTLYSDEEIENLVKKVTKKK
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PsmB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX127_LYCSI
Sequence: MMKVLVVVALLVTLISYSSSEGIDDLEADELLSLMANEQTRKECIPKHHECTSNKHGCCRGNFFKCKCQCTTVVTQDGEQTERCFCGTPPHHKAAELVVGFGKKIFG
What are the official names of this protein?
U1-lycotoxin-Ls1m, Toxin-like structure LSTX-A27.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 04 (U1-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1842_MYCTO
Sequence: MNLTDTVATILAILALTAGTGVFVAAEFSLTALDRSTVEANARGGTSRDRFIQRAHHRLSFQLSGAQLGISITTLATGYLTEPLVAELPHPGLVAVGMSDRVADGLITFFALVIVTSLSMVFGELVPKYLAVARPLRTARSVVAGQVLFSLLLTPAIRLTNGAANWIVRRLGIEPAEELRSARTPQELVSLVRSSARSGALDDATAWLMRRSLQFGALTAEELMTPRSKIVALQTDDTIADLVAAAAASGFSRFPVVEGDLDATVGIVHVKQVFEVPPGDRAHTLLTTVAEPVAVVPSTLDGDAVMAQVRASALQTAMVVDEYGGTAGMVTLEDLIEEIVGDVRDEHDDATPDVVAAGNGWRVSGLLRIDEVASATGYRAPDGPYETISGLVLRELGHIPVAGETVELTALDQDGLPDDSMRWLATVIQMDGRRIDLLELIKMGGHADPGSGRGR
What are the official names of this protein?
UPF0053 protein MT1890.
What is the protein family that this protein belongs to?
Belongs to the UPF0053 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.