PharMolix/UniProtQA huggingface dataset:
Protein: RL4_DEIRA
Sequence: MAQINVIGQNGGRTIELPLPEVNSGVLHEVVTWQLASRRRGTASTRTRAQVSKTGRKMYGQKGTGNARHGDRSVPTFVGGGVAFGPKPRSYDYTLPRQVRQLGLAMAIASRQEGGKLVAVDGFDIADAKTKNFISWAKQNGLDGTEKVLLVTDDENTRRAARNVSWVSVLPVAGVNVYDILRHDRLVIDAAALEIVEEEAGEEQQ
What is the function of this protein?
This protein is located close to the polypeptide exit tunnel, and interacts with the modified macrolide azithromycin, which blocks the tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: AAEB_YERPA
Sequence: MTHPSFIRLRFAFKLSFAIVAALFLGFHLQLETPRWSVLTAAIVSAGPAFAAGGEPFSGAIRHRGWLRIIGTFIGCIGGLVIIVLTIRAPVLTLMLCCLWAGICTWISSLVRVENSYAFGLAGYTALIIIVTTGETPLLTPQFAVERCSEIVLGIVCAVMADLLFSPRSIKQDIDRLVDKVLVDQYRLLQLCIQPAEKSEIDRAWNELVKNTTSLNGMRSYLMMESSRWQRCNRRLQVLHTESLALITQACETYLVMSNHPEVISAELKTMLSEPAQTPAEIHQQMKKLRQFIAASHSEAIPHTISSWVGAATRYLLLSKGIQTNSSINQVEEDILAGDAPVKPISAEGHHAMINGLRTGIATAIGGLFWLWTGWTSGAGCMVMIAVVTSLAMRTPNPRRMALDFLVGVIIALPIGALYFMFIIPSTQQSMLLLCISLGVLAFIIGIEVQKRRLGSLGTLASTINIIVLSNPMIFNVRQFLDSALGQIVGCFVSLIVLLLIRDNAKDRTGRTLLNRFVYSAVSALTTNKTKRGENHLPALYQQLNQLLMMFPADIDKYRLALTLIIAHQRLNRTEIPVNAELSAFHKQIRSTAERVITVNNDQKRRYYFARLLQELDQYQQKLVDYQAADAVIRPVKRLTEMLRKYQSALI
What is the function of this protein?
Forms an efflux pump with AaeA.  Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeB, pHBA efflux pump protein B.
What is the protein family that this protein belongs to?
Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ZDHC8_DROME
Sequence: MPKCDVKTRYIPATFAWIVLLLTTFLFFFYPCQFYVKSHPWVLAYQGVITFFVLANFTLATFMDPGIIPKASPDEDCEEELRAPLYKNAEINGITVKMKWCVTCKFYRPPRCSHCSVCNHCIETFDHHCPWVNNCIGRRNYRFFFFFLVSLSIHMLSIFSLCLVYVLKIMPNIKDTAPIVAIILMGLVTILAIPIFGLTGFHMVLVSRGRTTNEQVTGKFKGGYNPFSRGCWHNCCYTQFGPQYPSLLNPKKYASRRSQVQNQAISTICNDRSGQQTGAGSGAGGNGTAAVSGGGGGVGSGGGMRGTAVQYSPRSFYDASREKRGIQVKTYMAEGNGYNQRSGSTTLYSKLSPGRECSDTDLEPPPASQSQDCEPTPPLQRHNSSSFYLPQVSDSGGLNGSVSTGGGGGGDSPRHMRLYHPRHSPHARPRGLDPQRGYTSDALSPDHPVGYGVGVNGSQQQQQQALAAAAAAAAVAAQNQRSATTTATPTMQQRIKPLGVATPLVMASPVRRSNPGTPTQPRRPDFIGLNAQAVAQQQQQQQQAAAAAAAAYYEYTSGLPPQHPQAPSIQQQQQQLLLQQQRVLMQHQQQQQALQQQQQQQQQAAVHAAHPQHAALAQAAYGGSPQRRFLSEGELVRQGAGGGVAGGELSYARSNNTVDNIRELAGSPQRGVYMWKDTSPGFTNNAGQQQQQQQQAQQVVSSGIGSSAGTLSSSGAAAGVMPHAQYMTAGGGAHPLIMTHSRLQDYTIQQQQQQQQQQAAAAAAASYHRSNPTSPTTMPQVSGAGQSYILRYGGGGAVGAAGSSGSLASVTASNPATGGGGYQPALRGGVAVFPPNPMGNQGGGNLQTQPSPQIKRKQTPTRPMSFVRALEMADSMEMQSLEQQQNGGIPGSGSVGNNQQAGGGGGGHLMQSNASNSGTPDRASIYDMNYEISV
What is the function of this protein?
Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates and therefore functions in several unrelated biological processes (By similarity).  Regulates tissue growth possibly by regulating Ras64B protein stability (PubMed:30735487).  May regulate CG34450 mRNA levels (PubMed:30735487).
What are the official names of this protein?
Palmitoyltransferase ZDHHC8, Zinc finger DHHC domain-containing protein 8, Zinc finger DHHC-type containing 8.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: A1IB4_LOXHI
Sequence: WIMGHMVNAIYQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRSCLKWENYNDFLKGLRSATTPGNSKYQSKLILVVFDLKTGSLYDNQASEAGKKLAKNLLKHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFTDTLKQEGHPELLEKVGYDFSGNDAIGDVAKAYKKAGVSGHVWQSDGITNCLLRGLSRVKDAVANRDSGKGYINKVYYWTVDKRATTRDALDAGVDGVMTNYPDVIADVMNEAAYKNKVRLATYEDSPWVTFRK
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LhSicTox-alphaIA2biv, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GLND_XANOR
Sequence: MTDAPAERPDPSVAGDADWAAQARPLLVHADMRLRKRFDQGEPIERLVALRARAVDQLMRNAWTRCIPADSGLSLHAVGGYGRGELFPRSDVDVLVLGDSVAQQRHEQHLSRLFALLWDVGLPISHAVRSPTQCMVAAADQTVLTALIESRALVADAAARAALAAAIAPQRVWPPRDFFQAKREELLARHQRFGDTADNLEPDIKDGPGGLRDLQTLGCMALRAFGVKDVEALVGLGHVGCDEAAALRREREELARLRFGLHIVANRPEERLRFDYQKTLAERLGFADDLESLGVEKMMQRFYRSAALIRRISDRLLQRFEEQFDGEATPESLGGGFSLRRGYLAADSDSWPGDDVLQVFALFVHWAAHREVRGLHSLTARALAEVLREFPAYDVADATARELFMALLRGTRAVETLNRMARLGVLGQWIPAFASVSGRMQFDLFHVYTVDQHTLMVLRNIALFAAGRADERFSIAHEVWPRLRKPELLLLAGLFHDIAKGRGGDHSELGAVDTRAFCLAHRLSEGDTELVTWLVEQHLRMSVTAQKQDISDPEVIHRFATLVGTRERLDYLYLLTCADIAGTSPKLWNAWKDRLLADLYFAARRALREGVEHPPPREERLREARESARALMQAQGHDDATIDRQFAGMPDENFLRFRPEQLAWQAASLIEVEIAQTLVKARRAVPDNDALEVFVYSPDRDGLFAAIVATLDRKGYGIHRARVLDAPHDAIFDVFEVLPRDTYADGDPQRLAATLRQVLAGDLQQVRPARRAVPGQLRHFRFAPRVEFSESADGRRTRISLVAPDRPGLLADVAHVLRVQHLRVHDARIATFGERAEDQFQITDEHDRPLSESARQALRDALCACLDPV
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: SFTPA_CAVPO
Sequence: MWCSLALILILVTVSGIMCNRTDFCVGSPGIPGTPGSHGLPGRDGRDGVKGDPGPPGPMGPPGVMPGFPGCNGMNGIPGAPGERGDKGDPGERGPPGLPASLDEEIQTIFHNLKHKILQLTGVLSLQGSMLAVGDKVFATNGQSVDFNAIKETCARAGGDVAAPRNSEENTAISSIVKKYNIYSYLGLTEGHTPGDFHYLDGSPLNYTNWYPGEPRGRGKEKCAEMYLDGTWNDKNCLQSRLTICEF
What is the function of this protein?
In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.  Enhances the expression of MYO18A/SP-R210 on alveolar macrophages.
What are the official names of this protein?
Pulmonary surfactant-associated protein A, PSAP, PSP-A, SP-A.
What is the protein family that this protein belongs to?
Belongs to the SFTPA family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film.
Protein: TR113_RAT
Sequence: MVAVLQSTFAIIFSMEFIVGTLGNGFIILMTCIDWVRRRKISLVDQILTALAITRITLILLVFIDWWVSVLFPALHETGKILRMYFISWTVINHCNLWLTASLSIIYFLKIASFSSIIFLYLKFRVKNVVFVTLLVSLFFLFINTAIVNVYFDVCFDGVQRNVSQVSRLYNHEQICKFLSFTNPMFAFIPFVTSMATFFLLIFSLWRHLKNMKHNAEGCRDVSTIVHIRALQTIIVSVVLYSTFFLSFFVKVWSSGSPERYLIFLFVWALGNAVLPAHTFVLIWGNCRLRWASLSLMLWLRYRFKNIDV
What is the function of this protein?
Putative taste receptor which may play a role in the perception of bitterness.
What are the official names of this protein?
Taste receptor type 2 member 113, T2R113, Taste receptor type 2 member 30, T2R30.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RIBBA_MYCGI
Sequence: MTRLDSVERAVADIAAGKAVVVIDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVPLAGEICDRLGLLPMYAVNQDKHGTAYTVTVDAKVGVGTGISASDRATTMRLLADPDSVADDFTKPGHVVPLRAKDGGVLRRPGHTEAAVDLARLAGLQAAGTICEIVSQKDEGAMAQTDELRIFADEHDLALISIADLIEWRRKHEKHIARVAEARIPTRHGEFRAVGYTSIYEDVEHVALVKGDIAGPHGDGHDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGIVLYMRGHEGRGIGLMHKLQAYQLQDAGDDTVDANLKLGLPADARDYGTGAQILVDLGVRSMRLLTNNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDRMGHDLVGLDDFDEAVPGEFGGAV
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: MAGR1_XENRU
Sequence: GIGKFLHSAKKFGKAFVGEIMNS
What is the function of this protein?
Antimicrobial peptide.
What are the official names of this protein?
Magainin-R1.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family. Magainin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MDTI_SHIDS
Sequence: MAQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSQAAVLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWILFGQRLNRKGWIGLVLLLAGMIMVKLT
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtI.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NU1C_SOLTU
Sequence: MIIDTTEIETINSFSKLESLKEVYGIIWMLVPIVTLVLGITIGVLVIVWLEREISAGIQQRIGPEYAGPLGILQALADGTKLLLKENLIPSTGDTRLFSIGPSIAVISIFLSYSVIPFGDHLVLADLSIGVFFWIAISSIAPVGLLMSGYGSNNKYSFLGGLRAAAQSISYEIPLALCVLSISLLSNSSSTVDIVEAQSKYGFWGWNLWRQPIGFIVFLISSLAECERLPFDLPEAEEELVAGYQTEYSGIKFGLFYIASYLNLLVSSLFVTVLYLGGWNLSIPYIFVPELFGINKGGKVFGTLIGIFITLAKTYLFLFIPIATRWTLPRLRMDQLLNLGWKFLLPISLGNLLLTTSSQLLSL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic, NAD(P)H dehydrogenase subunit 1, NDH subunit 1, NADH-plastoquinone oxidoreductase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RLMB_NITEU
Sequence: MTHSQYIFGFHAITSRLRQHPDSIKEIYLDTNRHDQRARDLMSLAETTSTRLILCEQDRLCKMTGTTRHQGVAAHVTKLRRYATLEDLLEGLTEPALLLVLDGVKDPHNLGACLRVADAFGVHAVVVPKDRAVGLSATVHKVASGAVDTVPFFAVTNLARTLRELKEMGLWIVGTAADAPDTLDSVTLTRPLAWVLGAEDGGMRRLTREACDLLVSIPMSGSIESLNVSVSAGICLFETFRQHSQRTGSGLNVPAPKNAV
What is the function of this protein?
Specifically methylates the ribose of guanosine 2251 in 23S rRNA.
What are the official names of this protein?
23S rRNA (guanosine-2'-O-)-methyltransferase RlmB, 23S rRNA (guanosine2251 2'-O)-methyltransferase, 23S rRNA Gm2251 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 132L_IIV6
Sequence: MVKQRKTKYTSLPLSSLFEDASLSTKSPKREPSQEKEIKKEEIIKKNKPCKYEEECKRSDCVFLHPGEKMPEKPKPKETERRKTRMCKYVKKCNKGKNCPFAHDESEIYIPECRYGYKCKKQGKDNEPGECKFSHPPPPPPSPPSPPPKEEIKEEIFEFEITNFPTMNGEEPVALESSPTMDFSYLAEEDFLQKFEEKKSLIEESEKHRKCTINGSIDDMMKIFETMEGQDISQYYFNF
What are the official names of this protein?
Putative zinc finger protein 132L.
Protein: PSBN_PROMP
Sequence: MQTLSSAPDPAVSVAVTILAVLLALTGFGLWTAFGPKAAKLTDPWDDHDD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: DNAA_BRASO
Sequence: MTNSEQERWSRVKGRLRSTVGEDVYTSWFARMDLEAVQDESVHLSVPTRFLKSWIQAHYAERVLSAWQAEMPEVHRIDLSVRTAMRCATPAKEAPAAVEARRPERSDAKPVSDARAPVMTPVAASHDALGGSPLDPRLTFASFVVGRANTLAHAAARQVADGRRGDPVMFNPLYIHAGVGLGKTHLLQAVTWAGNAGGERKVLYLTAEKFMYGFVAALKSQTALAFKEALRGIDVLVIDDLQFLQGKSTQAEFCHTLNALIDAGRQVVIAADRPPSDLESLDDRVRSRLAGGLVVEMATLGEDLRLGILKSRVAAARAHHASFDVPEAVLDYLARSITHNGRDLEGAINRLLAHSKLNNQPVTLDMAEREVRDLVRPQEPKRIKIEDIQRVVARQYNVSRSDLLSSRRTANVVRPRQVAMYLAKTLTLRSLPEIGRRFGGRDHTTVLHAVRKIEALVGKDVALNDEVESLKRQLQD
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DN7E_SULAC
Sequence: MAKVRFKYKGEEKEVDTSKIKKVWRVGKMVSFTYDDNGKTGRGAVSEKDAPKELMDMLARAEKKK
What is the function of this protein?
Can constrain negative DNA supercoils.  May be involved in maintaining the integrity of the genome at high temperature.
What are the official names of this protein?
DNA-binding protein 7e, 7 kDa DNA-binding protein e, Sac7e.
What is the protein family that this protein belongs to?
Belongs to the 7 kDa DNA-binding/endoribonuclease P2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS25_AERPE
Sequence: MGGEDMAKKKAPSAKEGEKQQGFKEIIPEVTEKLVEQARKEVARERWVTPHKLAQKMGVKVSIARRVLRILEEEGVLVLFTRNRRSPLYLPKKKVPTAPPRGL
What are the official names of this protein?
30S ribosomal protein S25e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS25 family.
Protein: CSRN2_HUMAN
Sequence: MDAFTGSGLKRKFDDVDVGSSVSNSDDEISSSDSADSCDSLNPPTTASFTPTSILKRQKQLRRKNVRFDQVTVYYFARRQGFTSVPSQGGSSLGMAQRHNSVRSYTLCEFAQEQEVNHREILREHLKEEKLHAKKMKLTKNGTVESVEADGLTLDDVSDEDIDVENVEVDDYFFLQPLPTKRRRALLRASGVHRIDAEEKQELRAIRLSREECGCDCRLYCDPEACACSQAGIKCQVDRMSFPCGCSRDGCGNMAGRIEFNPIRVRTHYLHTIMKLELESKRQVSRPAAPDEEPSPTASCSLTGAQGSETQDFQEFIAENETAVMHLQSAEELERLKAEEDSSGSSASLDSSIESLGVCILEEPLAVPEELCPGLTAPILIQAQLPPGSSVLCFTENSDHPTASTVNSPSYLNSGPLVYYQVEQRPVLGVKGEPGTEEGSASFPKEKDLNVFSLPVTSLVACSSTDPAALCKSEVGKTPTLEALLPEDCNPEEPENEDFHPSWSPSSLPFRTDNEEGCGMVKTSQQNEDRPPEDSSLELPLAV
What is the function of this protein?
Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity (By similarity).  May play a role in apoptosis.
What are the official names of this protein?
Cysteine/serine-rich nuclear protein 2, CSRNP-2, Protein FAM130A1, TGF-beta-induced apoptosis protein 12, TAIP-12.
What is the protein family that this protein belongs to?
Belongs to the AXUD1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: UN93B_HUMAN
Sequence: MEAEPPLYPMAGAAGPQGDEDLLGVPDGPEAPLDELVGAYPNYNEEEEERRYYRRKRLGVLKNVLAASAGGMLTYGVYLGLLQMQLILHYDETYREVKYGNMGLPDIDSKMLMGINVTPIAALLYTPVLIRFFGTKWMMFLAVGIYALFVSTNYWERYYTLVPSAVALGMAIVPLWASMGNYITRMAQKYHEYSHYKEQDGQGMKQRPPRGSHAPYLLVFQAIFYSFFHLSFACAQLPMIYFLNHYLYDLNHTLYNVQSCGTNSHGILSGFNKTVLRTLPRSGNLIVVESVLMAVAFLAMLLVLGLCGAAYRPTEEIDLRSVGWGNIFQLPFKHVRDYRLRHLVPFFIYSGFEVLFACTGIALGYGVCSVGLERLAYLLVAYSLGASAASLLGLLGLWLPRPVPLVAGAGVHLLLTFILFFWAPVPRVLQHSWILYVAAALWGVGSALNKTGLSTLLGILYEDKERQDFIFTIYHWWQAVAIFTVYLGSSLHMKAKLAVLLVTLVAAAVSYLRMEQKLRRGVAPRQPRIPRPQHKVRGYRYLEEDNSDESDAEGEHGDGAEEEAPPAGPRPGPEPAGLGRRPCPYEQAQGGDGPEEQ
What is the function of this protein?
Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling.  Required for the transport of a subset of TLRs (including TLR3, TLR7 and TLR9) from the endoplasmic reticulum to endolysosomes where they can engage pathogen nucleotides and activate signaling cascades.  May play a role in autoreactive B-cells removal.
What are the official names of this protein?
Protein unc-93 homolog B1, Unc-93B1, hUNC93B1.
What is the protein family that this protein belongs to?
Belongs to the unc-93 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endosome. Lysosome. Cytoplasmic vesicle, phagosome. Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon cell-stimulation with CpG dinucleotides (By similarity). Colocalizes with LAMP5 in large endosomal intracellular vesicles.
Protein: ALL2_ASPFU
Sequence: MAALLRLAVLLPLAAPLVATLPTSPVPIAARATPHEPVFFSWDAGAVTSFPIHSSCNATQRRQIEAGLNEAVELARHAKAHILRWGNESEIYRKYFGNRPTMEAVGAYDVIVNGDKANVLFRCDNPDGNCALEGWGGHWRGANATSETVICDRSYTTRRWLVSMCSQGYTVAGSETNTFWASDLMHRLYHVPAVGQGWVDHFADGYDEVIALAKSNGTESTHDSEALQYFALEAYAFDIAAPGVGCAGESHGPDQGHDTGSASAPASTSTSSSSSGSGSGATTTPTDSPSATIDVPSNCHTHEGGQLHCT
What are the official names of this protein?
Major allergen Asp f 2, Allergen Asp f II.
What is the protein family that this protein belongs to?
Belongs to the ZPS1 family.
What are the subcellular locations of this protein?
Secreted. Note=Cell-associated.
Protein: RL19_PSEE4
Sequence: MTNKIIQQLEAEQMSKEIPTFAPGDTVVVQVKVKEGDRSRLQAFEGVVIAKRNRGLNSAFTVRKISSGVGVERTFQTYSPQIDSLAVKRRGDVRKAKLYYLRDLSGKAARIKEKLS
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: SYK_VIBPA
Sequence: MTDAVQNETVQEENKLIAERRAKLDEIRKSCKANGHPNDFRRDALAGDLQKEFGEKTKEELEELNHVVAIAGRIMAKRGPFLVIQETSGRIQAYADKEVQKELKEKYQGLDIGDIIGVKGALHKSGKGDLYVNMEEYELLTKALRPLPEKFHGLTDQEMRYRQRYVDLIVNEDSRNAFVVRSKVMSAIRNFMISKQFMEVETPMMHVIPGGASARPFITHHNALDMPMYLRIAPELYLKRLVVGGFDRVFEINRNFRNEGLSPRHNPEFTMMEFYMAYADYKDLMDFTEELLSSVALEVLGSTSMPYGEDTVEFGGKYARMSMFEAIKHYNPDHAQIQALTEEDLQNRELMVSIAKSVHVEVEPFWTCGQLLEEIFGETAEPKLMQPTFITGYPADISPLARRSDDNPFFTDRFEFFIGGREVANGFSELNDAEDQDARFKAQVEAKESGDDEAMFYDADYITALEHGLPPTAGQGIGIDRLVMLLTNTHTIRDVILFPAMRPQA
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTPB_MYCLE
Sequence: MTASLVEDTNNNHESVRRIQLDVAGMLCAACASRVETKLNKIPGVRASVNFATRVATIDAVDVAVDELRQVIEQAGYRATAHAESAVEEIDPDADYARNLLRRLIVAALLFVPLADLSTMFAIVPTNRFPGWGYLLTALAAPIVTWAAWPFHRVALRNARYRAASMETLISAGILAATGWSLSTIFVDKEPRQTHGIWQAILHSDSIYFEVAAGVTVFVLAGRFFEARAKSKAGSALRALAARGAKNVEVLLPNGAELTIPAGELKKQQHFLVRPGETITADGVVIDGTATIDMSAITGEARPVHASPASTVVGGTTVLDGRLVIEATAVGGDTQFAAMVRLVEDAQVQKARVQHLADRIAAVFVPMVFVIAGLAGASWLLAGASPDRAFSVVLGVLVIACPCTLGLATPTAMMVASGRGAQLGIFIKGYRALETINAIDTVVFDKTGTLTLGQLSVSTVTSTGGWCSGEVLALASAVEAASEHSVATAIVAAYADPRPVADFVAFAGCGVSGVVAEHHVKIGKPSWVTRNAPCDVVLESARREGESRGETVVFVSVDGVACGAVAIADTVKDSAADAISALCSRGLHTILLTGDNQAAARAVAAQVGIDTVIADMLPEAKVDVIQRLRDQGHTVAMVGDGINDGPALACADLGLAMGRGTDVAIGAADLILVRDSLGVVPVALDLARATMRTIRINMIWAFGYNVAAIPIASSGLLNPLIAGAAMAFSSFFVVSNSLRLSNFGLSQTSD
What are the official names of this protein?
Cation-transporting P-type ATPase B.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NADE_STAMF
Sequence: MVITIKDIINIPYDKAEKTIIEFIKNKIEEANLKGAVIGLSGGVDSSVTLLLTMKAIGIERVTALIMPDTRVTPKRDIEDALWLVKKYGIKYYVIRIDDIVDSYSAMPFFNINYNIPTGNLRARIRMNILYYYANLHNYIVVGTGDRSEILIGYFTKYGDGGVDILPIGSLFKTQVRKMGDYLGLPEKITSKPSSPALWLGHKAEEELGIKYETIDLVLYALFDKHIEPEKVPEHTGVDPSIVAKILEMHRKTRHKRLSPPIPSLPWVKEPIREI
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: RBL_DAPSP
Sequence: VGFKAGVKDYKLTYYTPDYDTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEENQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYLKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEDMMKRAVFARELGVPIVMHDYLTGGFTANTTLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDLIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREASKWSPELAAACEIWKEIKFEFEAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: BIOF_YERPY
Sequence: MSWQDKIAQGLQRRRDAAAYRTRQVNEGANGRWLQSGERQYLNFSSNDYLGLSQNDEVIAAWQQGARRYGVGSGGSGHVTGYSQPHARLEQRLADWLGYPRALLFISGYAANQAVLTALTDADDRILADKLSHASLLEAAAHSPAQLRRFQHNQPEALQNLLIKPCQGQTLVVTEGVFSMDGDSAPLAALQQQTSAAGGWLLVDDAHGIGVHGEEGRGSCWLQGVQPELLVVTFGKAFGLSGAAVLCQEPVAEYLLQYARHLIYSTAMPPAQACALQAALRQVQQGDALRQQLQQRIRQFRTAAAHLPLQLGASKTAIQPLLVGDNQQSLIWAEQLRAAGLWVTAIRPPTVPPGSARLRITLSAAHQPEDIDRLLEVLYGLCH
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: HSP57_ARATH
Sequence: MSIPHIAPVPHPRDGYYATNNPYQVNGPKGFTEFKYLEETHDLFVRLDFPGIQKESVIILLEPSKKAVIVTGEAPKESKHDSSHRKYGTATGLICDCCEISNIQCFVGDGVVRLILSKQKINLRVPIFCSCKITNLQNVLFFCLIFVGGARMPTDASPNIIRGYNPEDLSVELLLETSLRCFSIVNVSDIFHGFVLLIPIVAVAGGHPLAHLRGLNPEGCRGTDPFDPAFTGPTIRPHPSVLEGSTSAYETKQLSNGGLYLRIDMPGVPSDGFIVAVDGNGVVTIMGRAPATMHDSNGFYAMNNPYQANGPKGFAEFNQERDCGYPLTLLEPSKKAVTVTGDAAKSSKHDASNRNNNIHTFVEDGVVRLILSKKKIYPHAPNFCSFGGATIPTGDAPVADGTPYVNLLAHFRGLIPKGRRCTDPGDPAFTGPVVLPHPSVLEGPMMPYETKQLSNGGLYMRVDMPGVPSEKFMVAVDGDGVVTIMGRAPVTMHDTSGRTYVAKVANVPRGYDGGRIKLVPKHGVIRLTIPSN
What are the official names of this protein?
Putative 57 kDa heat shock protein.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.