PharMolix/UniProtQA huggingface dataset:
Protein: PYRR_PSEU2
Sequence: MSLPDPAELIRQMATDLNAHLSKRGISDPRFIGIRTGGVWVAQALLKALNNPAPLGTLDVSFYRDDFSQNGLHPQVRPSELPFEIEGQHLVLIDDVLMSGRTVRAALNELFDYGRPASVTLVCLLDLDAGELPVRPNVVGATLSLAPDERIKLSGPEPLALELQDLSTAL
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: PTPJ2_MDBVW
Sequence: MPIEDKRMRIMDFINFVRKPDSLSCIIQEYRAIVPEQEDGASKSCNQAVNRAQDENNALPIVRLVHSRVNLFSKEKVMSARYVDGYNHKQKFIITINSCENNTDKYLQMLWDNNVQIVVTTSSHAEKNNFNRFWSLNERTVITYNNFQIETLEIITKPHFVLTLLVLTDQKGQARKLSHFQYTAWPADGFSHDPKAFLDFFFNIDSLYADLRKHKTIGNVGPITIDCIDNNSSSEVFCVLDICLTEVKKTGMLSIANAVKKVRQKKYGCMNRLNDYVFCYHLIHAYLSMTFDIVKVR
What are the official names of this protein?
Probable tyrosine phosphatase protein J2, PTP-J2.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
Protein: RS6_CHLTA
Sequence: MKKKTGQLYEGAYVFSVTLSEDARRKALEKVTSGITNYGGEVLKIHDQGRKKLAYTIRGAREGYYYFIYFTVAPEAIAELWREYHLNEDLLRFMTLKASAVKEVLEFATLPE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: NQOR_ACIF2
Sequence: MSRILVLYHSLWGHVEQMAEAEAEGARSVSGIQVDVRRVPETMPAETLAAVHAKTHQAAPEAHPDDLANYDGIIFGTPTRFGNMTGQMRNFLDRTGNLWQEGRLVGKVGSVFVSTATQHGGQETTLTSFHTFLFHQGMLVVGVPYSCTELMNMDEISGGTPYGASTMSKGDGSRQPSANELTIARFQGRHVAEITRKLFG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: SNF5_HUMAN
Sequence: MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEVGNYLRMFRGSLYKRYPSLWRRLATVEERKKIVASSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDGNDEKYKAVSISTEPPTYLREQKAKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRDKKRTFPLCFDDHDPAVIHENASQPEVLVPIRLDMEIDGQKLRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLTFVPAIASAIRQQIESYPTDSILEDQSDQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSELGLGGEFVTTIAYSIRGQLSWHQKTYAFSENPLPTVEIAIRNTGDADQWCPLLETLTDAEMEKKIRDQDRNTRRMRRLANTAPAW
What is the function of this protein?
Core component of the BAF (hSWI/SNF) complex.  This ATP-dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation.  The BAF complex is able to create a stable, altered form of chromatin that constrains fewer negative supercoils than normal.  This change in supercoiling would be due to the conversion of up to one-half of the nucleosomes on polynucleosomal arrays into asymmetric structures, termed altosomes, each composed of 2 histones octamers.  Stimulates in vitro the remodeling activity of SMARCA4/BRG1/BAF190A.  Involved in activation of CSF1 promoter.  Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex).  During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state.  The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes.  As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF).  The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells.  The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).  Plays a key role in cell-cycle control and causes cell cycle arrest in G0/G1.
What are the official names of this protein?
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1, BRG1-associated factor 47, BAF47, Integrase interactor 1 protein, SNF5 homolog, hSNF5.
What is the protein family that this protein belongs to?
Belongs to the SNF5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NFYC_DICDI
Sequence: MENQIHSLLHFPSSASTGSTSNSHNNHHNNNNNNNYNNNNNNNINNINNNHHHHHNYKSIQQHSPHSSTPNISTENVDIYSSHEANSSNGYNNGNNFSYSMNGNFNYNFSPMNSPHHSHNHPDTSNNNMLPLNDSGIHFNQHQHPSSASSSSSSSSSSLSSSSHHHHSNHHHHHPNLHINLPPIPQYPSLNDSSSNGNGTPALSSPSSTTPHPTTPHPTTPTSTPNQRFQSNGSSSFQNQLQNHLENKLSSFWSSQLRDIHKTEDFKTHELPLARIKKIMKSDKDVNKISSEAPILFAKACEILILEMTHRSWVHTEMNKRRTLQRTDIINSLSRCETFDFLIDMLPRDEIKPSRKYLDELSKAQVITPEYLQYLQLQQMATENQQKNNQNNQNNQNKNNQQILPQQRNLNIPHSPQLQEQSSNNNNNNNNNNNNNNSVSVKRSYSMEIQNSSPLSTPKKRSNSQDYNFQYNENNHNQSSLSQTQQLQQLNQQQQQQQQQQQQQQQQQQQQQQQHSQQISQQIHHIPTPSNSSSSLPPLPPHNSNHAHNNNNNNNNNNNNNNNNNLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTFDYSFNDSKNDEHKVSLNESNFISTPTNDNIISSSPSSQVYYYSDN
What is the function of this protein?
Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters.
What are the official names of this protein?
Nuclear transcription factor Y subunit gamma, Nuclear transcription factor Y subunit C, NF-YC.
What is the protein family that this protein belongs to?
Belongs to the NFYC/HAP5 subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PB2_INBAC
Sequence: MTLAKIELLKQLLRDNEAKTVLKQTTVDQYNIIRKFNTSRIERNPSLRMKWAMCSNFPLALTKGDMANRIPLEYKGIQLKTNAEDIGTKGQMCSIAAVTWWNTYGPIGDTEGFEKVYESFFLRKMRLDNATWGRITFGPVERVRKRVLLNPLTKEMPPDEASNVIMEILFPKEAGIPRESTWIHRELIKEKREKLKGTMITPIVLAYMLERELVARRRFLPVAGATSAEFIEMLHCLQGENWRQIYHPGGNKLTESRSQSMIVACRKIIRRSIVASNPLELAVEIANKTVIDTEPLKSCLAAIDGGDVACDIIRAALGLKIRQRQRFGRLELKRISGRGFKNDEEILIGNGTIQKIGIWDGEEEFHVRCGECRGILKKSKMRMEKLLINSAKKEDMKDLIILCMVFSQDTRMFQGVRGEINFLNRAGQLLSPMYQLQRYFLNRSNDLFDQWGYEEPPKASELHGINELMNASDYTLKGVVVTKNVIDDFSSTETEKVSITKNLSLIKRTGEVIMGANDVSELESQAQLMITYDTPKMWEMGTTKELVQNTYQWVLKNLVTLKAQFLLGKEDMFQWDAFEAFESIIPQKMAGQYSGFARAVLKQMRDQEVMKTDQFIKLLPFCFSPPKLRRNGEPYQFLRLMLKGGGENFIEVRKGSPLFSYNPQTEVLTICGRMMSLKGKIEDEERNRSMGNAVLAGFLVSGKYDPDLGDFKTIEELEKLKPGEKANILLYQGKPVKVVKRKRYSALSNDISQGIKRQRMTVESMGWALS
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds a wide range of cap structures of target pre-RNAs which are subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: LGT_ECOSM
Sequence: MTSSYLHFPEFDPVIFSIGPVALHWYGLMYLVGFIFAMWLATRRANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPQFMADPLYLFRVWDGGMSFHGGLIGVIVVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPNFPFAMLFPGSRTEDILLLQTNPQWQSIFDTYGVLPRHPSQLYELLLEGVVLFIILNLYIRKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIVAGVIMMVWAYRRSPQQHVS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LTG31_ARATH
Sequence: MATHSSFTATTPLFLIVLLSLSSVSVLGASHHHATAPAPSVDCSTLILNMADCLSFVSSGGTVAKPEGTCCSGLKTVLKADSQCLCEAFKSSASLGVTLNITKASTLPAACKLHAPSIATCGLSVAPSTAPGLAPGVAAAGPETAGFLAPNPSSGNDGSSLIPTSFTTVLSAVLFVLFFSSA
What is the function of this protein?
Probable lipid transfer protein (By similarity).  Proteoglycan-like factor that exhibits xylogen activity consisting in mediating local and inductive cell-cell interactions required for xylem differentiation (PubMed:15215864, PubMed:21558309).
What are the official names of this protein?
Non-specific lipid transfer protein GPI-anchored 31, AtLTPG-31, Protein LTP-GPI-ANCHORED 31, Xylogen protein 1, AtXYP1.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: HS26M_ARATH
Sequence: MALARLALRNLQQKLSPSLMGQSCERGLVGNRHNPMKLNRFMATSAGEQEDKMNTEVSVSEKKSPRQNFPRRRGRKSLWRNTDDHGYFTPTLNEFFPPTIGNTLIQATENMNRIFDNFNVNPFQLMGQVKEQDDCYKLRYEVPGLTKEDVKITVNDGILTIKGDHKAEEEKGSPEEDEYWSSKSYGYYNTSLSLPDDAKVEDIKAELKNGVLNLVIPRTEKPKKNVQEISVE
What are the official names of this protein?
26.5 kDa heat shock protein, mitochondrial, AtHsp26.5.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PNP_ECOLU
Sequence: MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPIRPLFPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQYVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDQMLGAVVFGHEQQQVVIQNINELVKEAGKPRWDWQPEPVNEALNARVAALAEARLSDAYRITDKQERYAQVDVIKSETIATLLAEDETLDENELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDTFLFHYNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRDGISALQMDIKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKINPDKIKDVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKHAIRRIEEITAEIEVGRVYNGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQGRIRLSIKEATEQSQPAAAPEAPAAEQGE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABV_YERPE
Sequence: MIIKPRVRGFICVTAHPTGCEANVKKQIDYVTTEGPIANGPKRVLVIGASTGYGLAARITAAFGCGADTLGVFFERPGEEGKPGTSGWYNSAAFHKFAAQKGLYAKSINGDAFSDEIKQLTIDAIKQDLGQVDQVIYSLASPRRTHPKTGEVFNSALKPIGNAVNLRGLDTDKEVIKESVLQPATQSEIDSTVAVMGGEDWQMWIDALLDAGVLAEGAQTTAFTYLGEKITHDIYWNGSIGAAKKDLDQKVLAIRESLAAHGGGDARVSVLKAVVTQASSAIPMMPLYLSLLFKVMKEKGTHEGCIEQVYSLYKDSLCGDSPHMDQEGRLRADYKELDPEVQNQVQQLWDQVTNDNIYQLTDFVGYKSEFLNLFGFGIDGVDYDADVNPDVKIPNLIQG
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: MDHM_IMPCY
Sequence: VAILGAAGGIGQPLSLLMKDDLFNINAGIVK
What are the official names of this protein?
Malate dehydrogenase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PCNA2_SULTO
Sequence: MIKATYSSAKDFYSLLSGLLKVTDEIILNFTEDSIFSRYLTDDKVLMVIFKIPKEYLEDYTIDKPLGIKININDLKKILGKAKSKSATVTLEETEAGLKVTVRDEKTGTRSNIYIKGEKTSIDQLTEPKVNLSVTFTTDGDVLKDIARDLSLVGEEVEISADENTVTLSTEEAGRTYKSLLKQDKPLKSLNVESPSKAVYSIEVLKDVFKVTSISQNVTVGFGNNIPMKIEVPTDSGGQLIFWIAPRL
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication (By similarity).  Both trimeric complexes inhibit DNA ligase and both 3'-5' and 5'-3' activity of Hel308 (Hjm) helicase, but stimulate Hjc, the Holliday junction cleavage enzyme.
What are the official names of this protein?
DNA polymerase sliding clamp 2, Proliferating cell nuclear antigen homolog 2, PCNA2.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: LEU3_KAZEX
Sequence: MAQTTKHIVVLPGDHVGQEITEEAIKVLNAISSVRPNVNFDFQHHLIGGAAIDATGVPLPDEALEASKKADAVLLGAVGGPKWGTGSVRPEQGLLKIRKELQLYANLRPCNFASDSLLDLSPLKPEIVKGTDICIVRELVGGIYFGERKEDEGDGVAWDSEKYSVSEVQRITRMAGFLALQHNPPLPVWSLDKANVLASSRLWRKTVEETIKNEFPTLTVQHQLIDSAAMILVKNPTHLNGVVIANNMFGDIISDEASVIPGSLGLLPSASLASLPDTNTAFGLYEPCHGSAPDLPKGKVNPVATILSVAMMLKLSLNMTEEGIAVEKAVKQVLDSGVRTADLRGSNSTSEVGDAIAKAVKEILA
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity).
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, IMDH, Beta-IPM dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
Protein: NFUA_HAEIG
Sequence: MEQATQQIAISDAAQAHFRKLLDTQEEGTNIRIFVVNPGTPNAECGVSYCPPNAVEESDIEMKYNTFSAFIDEVSLPFLEEAEIDYVTEELGAQLTLKAPNAKMRKVADDAPLIERVEYVIQTQINPQLANHGGRITLIEITEDGYAVLQFGGGCNGCSMVDVTLKDGVEKQLVSLFPNELKGAKDITEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: EPMA_ECO81
Sequence: MSETASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEIDPLSADKTQLREVAAKLDLSNVADTEEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPASQASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQHPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA
What is the function of this protein?
With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P) on 'Lys-34'.  Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of EF-P 'Lys-34'.
What are the official names of this protein?
Elongation factor P--(R)-beta-lysine ligase, EF-P--(R)-beta-lysine ligase, EF-P post-translational modification enzyme A, EF-P-lysine lysyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
Protein: ACSA_BRUME
Sequence: MSEKLYPVLPEAKKNTLIDNETYLEWYEESVSDPDGFWAKHGRRIDWFKPFTKVKNTDFNGDVTIKWYEDGVTNVSYNCIDRHLKSRGDKVAIIWEGDNPYIDKKITYRELYENVCRMANVLKKHGVKKGDRVTIYLPMIPEAAYAMLACARIGAVHSVVFAGFSPEALAGRIVDCESTFVITADEGVRGGKPVALKENTDTAIDIAAKQYVMVNKVLVVRRTGGKVSWGRGRDLWYHQEVASVEPHCEPEPMNAEDPLFILYTSGSTGKPKGVLHTTGGYLVYASMTHQYVFDYHDGEIYWCTADVGWVTGHSYIVYGPLANGATTLMFEGVPNFPDQGRFWEVVDKHHVNIFYTAPTALRALMGAGDEFVTRSSRSTLRLLGSVGEPINPEAWEWYYNVVGDQKCPIVDTWWQTENGGILITPLPGATDLKPGSATRPFFGVKPVLVDNEGNVQEGVADGNLCISDSWPGQMRTVYGDHKRFIETYFSTYKGMYFSGDGCRRDEDGYYWITGRVDDVLNISGHRLGTAEIESALVSHHSVSEAAVVGYPHPIKGQGIYCYVTLMTGADAQDPDELRKELVQHVRKEIGPIATPDKIQFAPGLPKTRSGKIMRRILRKIAEDEFGALGDTSTLADRGVVDDLIENRQNKK
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: RSMG_RICAH
Sequence: MEVSREIIEKLEIFQKLVKKWNKSINLVSGNTIHNFWQRHILDSLQLMQYIDNKEIHLVDIGSGAGFPGIVLSIAGVAKVSLIEADLRKCIFLEKASKISNNNIQIINQRIEKVAIDCSILTCRAFSKLNTIFNCIKNISVQEKVLLLKGKNYLTEIVAAKEMWLFDYLIHQSITCEEGKILEVSNLTKII
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCD22_ANOGA
Sequence: MDDIDNIILHSLRQIDCDLDEDLQGLEQFTPAVLVRTVSKCLLLIDPSLDLPQTLPPGMAQRFTVTARLAEACTAVGYRRDIGYQTFLYSNVAEVRRVFMFLIEQLPKDSTDAADPEAPLDRVTDLENRILDSMRQQLRGRKDPATPLDLRNATLGWAGSRSRANIPFVTQSDVTAGTGLRGRKWLQTILICVFFLALAQKLSNTGYAGAGFGRRKRMKWIGGRQTTDDSILKLQAYYAQNKAQCPLAEELEEAAETPDRLGQLDALEQEIAAIETAISESRRQRRELHAKRRTVAESAQAVESVAEKLKEEKKIKERTHILLENPEVNVAKLESIIAAAGEKMKKLQSQWEAHRAPLVATLEEHQAKNSDQIESARHKSEEVIVDLQTKSALHARLVQEYERMGRTVSRTAYTSRILEIIGNIRKQKTDIDKILHDTRSLQKEINSITGQLDRQFTVTDDLIFRNAKRDEYCKRAYILLVALHTECSELTALVQETGTVKREVRELEDQIENEKDRNVVTNLAQIGQDLEEMQRESRRLEEAIQQLELSAGRNGTK
What are the official names of this protein?
Coiled-coil domain-containing protein 22 homolog.
What is the protein family that this protein belongs to?
Belongs to the CCDC22 family.
Protein: PPIL1_GIBZE
Sequence: MTTNIVLETTMGSLILELYTTHAPKTCNNFTTLVRRGYYDNTIFHRIIPNFMVQGGDPTGTGRGGSSIFGEKFEDEIDPGLKHTGAGILSMANAGPNTNGSQFFVTLAPTPWLDGKHTIFGRVKSGMGTIKRMGLVKTGSEDRPVEEVKIVKARVVEEEEQI
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase-like 1, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIL1 subfamily.
Protein: RS15_ACAM1
Sequence: MALLQEKKHEIINAYQVHETDTGSADVQVAMLTERISKLSEHLKTNKKDHSSRRGLLKMIGQRKRLLTYIMKKDQAHYRELIKRLGIRG
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RS7_RHOE4
Sequence: MPRKGPAPKRPLINDPVYGSPLVTQLVNKILLDGKKSTAERIVYQALEQAREKTGTDPVVTLKRALDNVKPALEVRSRRVGGATYQVPVEVRPGRSTTLALRWLVTFSRARREKTMVERLANELLDASNGLGAAVKRREDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: KIF2A_BOVIN
Sequence: MVTSLNEDNESVTVEWIENGDTKGKEIDLESIFSLNPDLVPDEDIEPSPETPPPPTSSAKVNKIVKNRRTVASIKNEPPPRDNRVVGSARARPSQLPEQSSSAQQNARRKSNCVKEVEKLQEKREKRRLQQQELREKRAQDVDATNPNYEIMCMIRDFRGSLDYRPLTTADPIDEHRICVCVRKRPLNKKETQMKDLDVITIPSKDVVMVHEPKQKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVETIFERGMATCFAYGQTGSGKTHTMGGDFSGKNQDCSKGIYALAARDVFLMLKKPNYKKLELQVNATFFEIYSGKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSCRTSGQTSANAHSSRSHAVFQIILRRKGKLHGKFSLIDLAGNERGADTSSADRQTRLEGAEINKSLLAHKECIRALGRNKPHTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCENTLNTLRYANRVKELTVDPTAAGDVRPIMHHPPNQIDDLEAQWGVGSSPQRDDLKLLCEQNEEEVSPQLFTFHEAVSQMVEMEEQVVEDHRAVFQESIRWLEDEKALLEMTEEVDYDVDSYATQLEAILEQKIDILTELRDKVKSFRAALQEEEQASKQINPKRPRAL
What is the function of this protein?
Plus end-directed microtubule-dependent motor required for normal brain development.  May regulate microtubule dynamics during axonal growth.  Required for normal progression through mitosis.  Required for normal congress of chromosomes at the metaphase plate.  Required for normal spindle dynamics during mitosis.  Promotes spindle turnover.  Implicated in formation of bipolar mitotic spindles.  Has microtubule depolymerization activity (By similarity).
What are the official names of this protein?
Kinesin-like protein KIF2A.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. MCAK/KIF2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Note=Localized to the spindle microtubules and spindle poles from prophase to metaphase. Efficient targeting to spindle microtubules and spindle poles requires the kinase activity of PLK1. Recruited to mitotic spindles by interaction with PSRC1 (By similarity).
Protein: NADK1_BACCZ
Sequence: MKFTIMSKGDQSSDTLASTMKEYLLDFGFIMDEQEPDIVISVGGDGTLLYAFHRYYNRLDETAFVGVHTGHLGFYADWLPTEVEKLVIAIAKTPFQVVEYPLLEVIIRYMNGSKESQYLAMNEATVKSAEGTLVTEVEIRGEYFETFRGDGLCISTPSGSTAYNKALGGAIIHPSIEAIQIAEMASINNRVFRTVGSPLVLPKHHTCVLKPTAGMNLQITVDHLTMVHQDVKSIQYRVANEKVRFVRFRPFPFWKRVRDSFVADK
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase 1, ATP-dependent NAD kinase 1.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU1_CAMJD
Sequence: MKNNKIIIFDTTLRDGEQALGSSLGINQKLQIALALENLGVDVIEAGFPVSSQGDFKAVQKIASKVKNSTICALSRALDKDIDMAYEALKVAKHFRIHTFIATSTLHIQDKLKKDFDEILSMAKRAIIRARSYTDDVEFSCEDAGRTPIDNLCFMVENAIKAGAKTINIPDTVGYTLPSEFANIIKILFNKVPNIDKAIISVHCHNDLGMATGNSLSAILQGARQIECTINGLGERAGNCALEEVVMAIKTRKDYLQGFYTDIKCENISKTSKLVSAITNESIPSHKAIVGSNAFSHSSGIHQDGVLKNRQTYEIISPSAIGIHENRMLMTARSGRAMIKTCLENLGYDENTYNLDDVYERFLRLADKKGQVYDYDLEALMFLSYESEEENEFVLEKLSVISGNIPTACVCMRIKEELKTEACTGNGPVEAVFNCIARITNLKPVLKAYSINAKSSGVDAQGQVDVDLEFKGRKFHGKGLSTDVIEASAQAFVSAYNAIYRSLKVEERKMA
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: ESPB1_CANLF
Sequence: MNPWSSYLLGWTTFLLYFYETSGKIPNLSSLGKHEFTKPWISIKEDQKDSCVFPFVYKGSSYFSCIKTNSFSPWCATRAVYNGQWKFCMADDYPRCIFPFIFRGKSHNSCITEGSFLRRLWCSVTSSFDENQQWKYCETNEYGGNSFSKPCIFPSIFRNSTIFECMEDENNKLWCPTTENMDEDGKWSLCADTRISSLVPGFPCHFPFSYKNKNYYNCIGKGTKENLTWCATSYNYDRDHTWVYC
What is the function of this protein?
Binds to spermatozoa upon ejaculation and may play a role in sperm capacitation.  Has phosphorylcholine-binding activity (By similarity).
What are the official names of this protein?
Epididymal sperm-binding protein 1, CeE12, E12a, Epididymal secretory protein 12.
What is the protein family that this protein belongs to?
Belongs to the seminal plasma protein family.