PharMolix/UniProtQA huggingface dataset:
Protein: SELG_DROME
Sequence: MVYIDHNGRVWEKRPWDWRRIVELFVGIWFAIKQLFLTFLAPFTGNNNQANPRRGNGWGGGGGWGGGGGGGGGGGGGRPGSGSGGLRPNRRIGRIQPTMSCNMPAGGGUG
What is the function of this protein?
Plays a role in the life span.  May be involved in regulating the redox state of the cell and possesses anticarcinogenic properties.
What are the official names of this protein?
Glycine-rich selenoprotein, G-rich selenoprotein, dSelG.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type III membrane protein.
Protein: RS18B_CANAL
Sequence: MPLVVQEQGSFQHILRLLNTNIDGRIKIMYALTKIRGVGRRYANLVCKKADVELTKRAGELTQEELERIVTIMQNPTNYKIPAWFLNRQKDQVDGKDYHVLANNLESKLRDDLERLKKIRSHRGIRHFWGLKVRGQHTKTTSRGR
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
40S ribosomal protein S18B.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RF2_SALTY
Sequence: MFEINPVNNRIQDLTERTNVLRGYLDYDAKKERLEEVNAELEQPDVWNEPERAQALGKERSSLEAIVDTLDQMTQGLDDVSGLLELAVEADDEETFNEAVAELNTLEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLLRMYLRWAEARGFKTEVIEESEGEVAGIKSATIKISGEYAYGWLRTETGVHRLVRKSPFDSGGRRHTSFSSAFVYPEVDDDIDIDINPADLRIDVYRASGAGGQHVNRTESAVRITHIPTGIVTQCQNDRSQHKNKDQAMKQMKAKLYELEMQKKNAEKQAMEDTKSDIGWGSQIRSYVLDDSRIKDLRTGVETRNTQAVLDGSLDQFIEASLKAGL
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATRX_MPV15
Sequence: MEAYLVEMYHGVPYTAAVQLNLVEKHSANISLTVWIPMFQTSLPKNSVMDLLHDVTVICTQISTVHGPMIKVDLSSSNAGLATMPRQFLINAIIALDDWGNMDYEVPVAFDKKSFCVTILKPKNMLYTVPSITPTNRPTHELIAVCSFHNRVTLKSFNIPVFIRALYIRQQGLDSVEQAISSDVDHAITTARVAPYAGLTLVINITSTKGAFKLLKAGSQILAELGPYLTQVSLHDVIMNWKHTGTSYILKSSSTSG
What is the function of this protein?
Plays a crucial role in virus assembly into filaments and budding.  Early in infection, localizes in the nucleus where it may inhibit host cell transcription.  Later in infection, traffics to the cytoplasm to associate with inclusion bodies, the site of viral transcription and replication.  During virus assembly and budding, acts as a bridge between the nucleocapsid and the lipid bilayer.
What are the official names of this protein?
Matrix protein, M protein.
What is the protein family that this protein belongs to?
Belongs to the pneumovirinae M protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Host nucleus. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=In the cytoplasm, associates with inclusion bodies. During bud formation, associates at the inner side of the plasma membrane of infected cells.
Protein: MNHB1_STAA3
Sequence: MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGLLFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFDIPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit B1, Mnh complex subunit B1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: INT3_DROYA
Sequence: MEQQQSKNIVHVSKLFVCTAVDCKDDIEEKFERSFVTLQMQISGLSDKEMHDMLSQAVCKDKQHEEISIGFLYIMLTDPSMAPKTYRDVTLVSRDGMNGIVTNLTFLVAEKYTKLTEVARRQLIWLLREFVKHQVLSVENVIWNCLRQAGGGDVSSRNLFLIESLLDIFIEFRTWLEGNPFLVQSTVYSFVRLIEDHANPALMSLRQKEVKFTISLIRERFHDIIPLGRDFVRLLQNVARIPEFEQLWRDLIFNPKILHQTFNGIWQLLHIRTSRRFLQCRLLPEMERKISFLASSVKFGNQKRYQDWFQEKYFATPESHSLRSDLIRFIINVIHPTNDMLCSDIIPRWAIIGWLISSCTNPIASANAKLSLFYDWLFFDPAKDNIMNIEPGILVMYHSIRNHPFVSSTLLDFLCRITKNFFVKHEDKIRIGVYNSLKLILEKQVIPNLQPLFESPKLDRELRNLIRDNFREFLSPSANLGQLLYPSMHPAQGYIIKKESDQRILHCENMDLHETGLINTSGSNISMLDEDIKISLVPTDLEIESVFSDETAENLKRVHNIEENTDDDDDLPLSKVRLKEKPRVELAESIAESFDAFVTKRNSYTWEAFLKDFRPLPASAFEEFQLNYVISNTVLILRETLPQQNIFSESKTEEKHLAKSISYPLYGLFRFLYENDEKSKKPFQILLSEICEGIPEIGYLLLYFMKIYCKLQTRKNSQHSYQFKTTIYRQICDAVDEKIGNCLIRDLDLLEKENTNIFLWLLPDIYREFKSIATNNTDLLRITLRCIDAKNVRDILYSVAQGKLTIFKQDGLIDCIRESLDFETYEQFCLWQIVQAHDVPLRCIQDLLPELEAGSHPEALSHFLLLLKNEEPTNEIIRLMLSRETKSKGDPFVTSALRFWCQRYEEKLSEIIASLLTSKYPSSSPNKRKRPPKGISVSTSTPSADQVLNHLEHYRRSCRHGTGTGLYVHDMMQRALQSAYSHSNDSTKKQFSDLFALAAEEDTTVGRRGGSGRGRKQPGSKKDVSNHGTSKKNAEMVKTIYSSDENSSEEDWSKSKMTQTAKRRKKANNDSD
What are the official names of this protein?
Integrator complex subunit 3 homolog, SOSS complex subunit A homolog.
What is the protein family that this protein belongs to?
Belongs to the Integrator subunit 3 family.
Protein: P12I_HTL1C
Sequence: MLFRLLSPLSPLALTALLLFLLSPGEVSGLLLRPLPAPCLLLFLPFQILSNLLFLLFLPLFFSLPLLLSPSLPITMRFPARWRFPPWRAPSQPAAAFLF
What is the function of this protein?
p12I is a modulator of T-lymphocyte proliferation and immune function and may contribute to establish a persistent infection.  Binds and down-modulates cell surface expression of interleukin-2 receptors IL2RB and IL2RG.  Also down-modulates cell surface MHC-I molecules by binding to free immature MHC-I heavy chains in the ER and targeting them to the proteasome for degradation.  Binding to IL2RB mediates recruitment of JAK1 and JAK3.  As a result of this interaction, p12I increases DNA-binding and transcriptional activity of STAT5 (By similarity).
What are the official names of this protein?
Accessory protein p12I.
What is the protein family that this protein belongs to?
Belongs to the HTLV-1 accessory protein p12I family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Multi-pass membrane protein. Host Golgi apparatus, host cis-Golgi network membrane; Multi-pass membrane protein.
Protein: POL_SFV1
Sequence: MDPLQLLQPLEAEIKGTKLKAHWDSGATITCVPEAFLEDERPIQTMLIKTIHGEKQQDVYYLTFKVQGRKVEAEVLASPYDYILLNPSDVPWLMKKPLQLTVLVPLHEYQERLLQQTALPKEQKELLQKLFLKYDALWQHWENQVGHRRIKPHNIATGTLAPRPQKQYPINPKAKPSIQIVIDDLLKQGVLIQQNSTMNTPVYPVPKPDGKWRMVLDYREVNKTIPLIAAQNQHSAGILSSIYRGKYKTTLDLTNGFWAHPITPESYWLTAFTWQGKQYCWTRLPQGFLNSPALFTADVVDLLKEIPNVQAYVDDIYISHDDPQEHLEQLEKIFSILLNAGYVVSLKKSEIAQREVEFLGFNITKEGRGLTDTFKQKLLNITPPKDLKQLQSILGLLNFARNFIPNYSELVKPLYTIVANANGKFISWTEDNSNQLQHIISVLNQADNLEERNPETRLIIKVNSSPSAGYIRYYNEGSKRPIMYVNYIFSKAEAKFTQTEKLLTTMHKGLIKAMDLAMGQEILVYSPIVSMTKIQRTPLPERKALPVRWITWMTYLEDPRIQFHYDKSLPELQQIPNVTEDVIAKTKHPSEFAMVFYTDGSAIKHPDVNKSHSAGMGIAQVQFIPEYKIVHQWSIPLGDHTAQLAEIAAVEFACKKALKISGPVLIVTDSFYVAESANKELPYWKSNGFLNNKKKPLRHVSKWKSIAECLQLKPDIIIMHEKGHQQPMTTLHTEGNNLADKLATQGSYVVHCNTTPSLDAELDQLLQGHYPPGYPKQYKYTLEENKLIVERPNGIRIVPPKADREKIISTAHNIAHTGRDATFLKVSSKYWWPNLRKDVVKSIRQCKQCLVTNATNLTSPPILRPVKPLKPFDKFYIDYIGPLPPSNGYLHVLVVVDSMTGFVWLYPTKAPSTSATVKALNMLTSIAIPKVLHSDQGAAFTSSTFADWAKEKGIQLEFSTPYHPQSSGKVERKNSDIKRLLTKLLIGRPAKWYDLLPVVQLALNNSYSPSSKYTPHQLLFGVDSNTPFANSDTLDLSREEELSLLQEIRSSLHQPTSPPASSRSWSPSVGQLVQERVARPASLRPRWHKPTAILEVVNPRTVIILDHLGNRRTVSVDNLKLTAYQDNGTSNDSGTMALMEEDESSTSST
What is the function of this protein?
Integrase catalyzes viral DNA integration into the host chromosome, by performing a series of DNA cutting and joining reactions.  This enzyme activity takes place after virion entry into a cell and reverse transcription of the RNA genome in dsDNA.  The first step in the integration process is 3' processing.  This step requires a complex comprising at least the viral genome, matrix protein, and integrase.  This complex is called the pre-integration complex (PIC).  The integrase protein removes 2 nucleotides from the 3' end of the viral DNA right (U5) end, leaving the left (U3) intact.  In the second step, the PIC enters cell nucleus.  This process is mediated through the integrase and allows the virus to infect both dividing (nuclear membrane disassembled) and G1/S-arrested cells (active translocation), but with no viral gene expression in the latter.  In the third step, termed strand transfer, the integrase protein joins the previously processed 3' ends to the 5' ends of strands of target cellular DNA at the site of integration.  It is however not clear how integration then proceeds to resolve the asymmetrical cleavage of viral DNA.
What are the official names of this protein?
Pro-Pol polyprotein, Pr125Pol.
What are the subcellular locations of this protein?
[Integrase]: Virion. Host nucleus. Host cytoplasm. Note=Nuclear at initial phase, cytoplasmic at assembly. SUBCELLULAR LOCATION: [Protease/Reverse transcriptase/ribonuclease H]: Host nucleus. Host cytoplasm. Note=Nuclear at initial phase, cytoplasmic at assembly.
Protein: Y2143_VIBVY
Sequence: MHSDITPIHTHKKYWAECFGTAPFLPTSRKEMDALGWDSCDIVLVTGDAYVDHPSFGMAIIGRLLEAQGFRVGIIAQPQWQDKTDFMSLGKPNLFFGVTSGNMDSMINRYTSDRKLRHDDAYTPNNEGGKRPDRATLVYSQRCREAYKDVPIVLGGIEASLRRVAHYDYWSDKVRRSVLLDAKADILLFGNAERALVEVAHRLAEGEEIAQMTNIRGTAVNLAAEPEGYTIIDSSRIEKPRKEAFIPPNPYEVETQCETKSEEPKAQPITIRPSRHDAATTAVRLPSFEKLQNDRILYAHASRILHLETNPYSGRALIQRHGNRELWVNQAPIPLTTEEMDYVFGLPYARVPHPKYGKAKIPAYDMIKTSVNIMRGCFGGCSFCSITEHEGRIIQNRSQESILTELEEIRDKVPGFTGTISDLGGPTANMYRLGCSDPKAEANCRRPSCVFPGICNKLNTDHKHTIDLYRAARQVKGVKKVMIASGVRYDLAIESPEYVKELVTHHVGGYLKIAPEHTEKGPLDLMMKPGMGTYDRFKEMFDKYSQEAGKKQYLIPYFISAHPGTTDEDMLNLALWLKKNNYECDQVQNFYPSPMCNATSMYYSETNPLKRVKYKQREDVPVAKGDRQRRLHKALLRYHDPANWPLIREALITMGKKYLIGDKPGCLVPAEDVDARTPAQRRKSGRHGANRFATKHTSTQPGFPGDKANAGSGKKPTRGGQSNSAPSRSGSATGGKHPQRSGANTGGKSSGGKNSPRAGGRNQPSRAR
What are the official names of this protein?
UPF0313 protein VV2143.
What is the protein family that this protein belongs to?
Belongs to the UPF0313 family.
Protein: Y3788_MYCTU
Sequence: MSEKVESKGLADAARDHLAAELARLRQRRDRLEVEVKNDRGMIGDHGDAAEAIQRADELAILGDRINELDRRLRTGPTPWSGSETLPGGTEVTLRFPDGEVVTMHVISVVEETPVGREAETLTARSPLGQALAGHQPGDTVTYSTPQGPNQVQLLAVKLPS
What are the official names of this protein?
Uncharacterized protein Rv3788.
Protein: GMFB_BOVIN
Sequence: MSESLVVCDVAEDLVEKLRKFRFRKETNNAAIIMKIDKDKRLVVLDEELEGISPDELKDELPERQPRFIVYSYKYQHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNKLVQTAELTKVFEIRNTEDLTEEWLREKLGFFH
What is the function of this protein?
This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells.
What are the official names of this protein?
Glia maturation factor beta, GMF-beta.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family. GMF subfamily.
Protein: SFSA_ALCBS
Sequence: MKFDPPLETVTLLRRYKRFMADVVRADGSEITVHCPNTGSMKNCVLGGPQQALISDSGNPKRKYRHTLEALQVAHGHWAGVNTARPNALVEEAVRAGQFPMLDSTSGVEREVKYGDSRFDLALGERADPHTFIEVKNVTLGPGPDDKDDGVIAFPDSVTERGQKHLQTLMDVVASGKRAVLFFCVQHSGATAARPADEIDARYGQLLREAIENGVEVLAWKSEVSAQCFRLKEPLPLDL
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: LICH_MACFA
Sequence: MKMRFLGLVVCLVLWTLHSEASGGKLTAVNPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALAPVVSVDFCTSPMAKLGRLPDLLIKDLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDINILLTQITNLVFHESIPEWEHLDFIWGLDAPWRLYNKIINLMKKYQ
What is the function of this protein?
Catalyzes the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol.
What are the official names of this protein?
Lysosomal acid lipase/cholesteryl ester hydrolase, Acid cholesteryl ester hydrolase, LAL, Cholesteryl esterase, Lipase A, Sterol esterase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Lysosome.
Protein: HOL1_ARATH
Sequence: MAEEQQNSDQSNGGNVIPTPEEVATFLHKTVEEGGWEKCWEEEITPWDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITDHVGGPPYKVDVSTFEEVLVPIGFKAVSVEENPHAIPTRKGKEKLGRWKKIN
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase.  Involved in glucosinolate metabolism and defense against phytopathogens.  Highly reactive to thiocyanate (NCS(-)) derived from myrosinase-mediated hydrolysis of glucosinolates upon tissue damage.
What are the official names of this protein?
Thiocyanate methyltransferase 1, Protein HARMLESS TO OZONE LAYER 1, AtHOL1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
Protein: D63_SSV1
Sequence: MSKEVLEKELFEMLDEDVRELLSLIHEIKIDRITGNMDKQKLGKAYFQVQKIEAELYQLIKVS
What is the function of this protein?
This protein may be involved in virus assembly.
What are the official names of this protein?
Protein D-63.
Protein: EX7L_PSET1
Sequence: MFSKPLQTIYTVSRLNREIRALLEQGFASLVLTGEISNFITPASGHWYFSLKDDKAQIKAAMWRGNNRNQSYRPINGAQVTVKARVSLYEPRGDYQLIVEHMEPAGEGQFKQEFDALKMRLAAEGLFSSVYKKPLPQNINRIGVITSATGAAIKDILTVLKRRAPQLEVIIYPAMVQGKDAHLQLIKQIELANIRSEVDVLILGRGGGSLEDLWCFNHEQLARAIFNSQLPIVSAVGHEIDTTISDYVADVRAATPSAAAELVSPNTQELHNKVTQLVNRLANAFKHDMSEKRAQALQLQHRLNLCHPRNQLNQKAQRLDELSIALQQAMRNSLYQQERTLNNLTPRLMRQSPDKKLTQASHQLAQLQTRLNQAIQQQLQQANNSLALQASRLDSVSPLNVLARGYSITKTDKQKVVKSVADVKVGDTLITELVDGTLHSQVLS
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2530_MARMS
Sequence: MKQHLIVEVFRSSKHDGMYLYVEKSKGLKEIPEELMTRFGKGISAMTMLLTNESKLARATPENVTKGIREKGFYLQLPPAKDEYLLDLYKTPTEAVY
What are the official names of this protein?
YcgL domain-containing protein Mmwyl1_2530.
Protein: 3004L_ASFM2
Sequence: MLSLFNIALKALIMKHNVEFLKRDKEILTHLGLCCKDYVIIDKCSECGNICPNGQQHGDTCININYLLIYAVKRDNYMLAYRLLSWGANEKFANCFRRPLPNLKPPLPKKELTPKEIKQLAYDHFHNDSELITIFEVFRKCRHINDCLNFFYKKNTEFEIYFARLHVYSKTFYGKGWYWFCIFIAVKHSMEHALKKITKTFTPTFYNKTTLNLVLFLSACFYENVEWMKNFFYKGNKKIQQRMLNYGMEWAATHGKVRTFICCYTLGGTASLKLYQKAYQNEKFMIMALCSYLGNIQINNPWESLNPYTMVQNKEKFLPLKFSEETQYFYI
What are the official names of this protein?
Protein MGF 300-4L, L2HL.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 300 family.
Protein: FLZ13_ARATH
Sequence: MILSKRPHLMIRKLSEMLVPRSRSAAIKPEEYTASPRSPLDLNFPSPVHSKRFGSGGVGLGIVAALEETSNGINRHDPVRYSGRFRCPEIDLSDEEYTYVTSPNGPTKVYYNDDGFELSENDYRRVHKPMVTVDEPPVIERQSVRGPTEFLSSCCLCKKKLQGKDIYMYKGEMGFCSAECRSVQIMNDERQEQCKTQVSRNADVLSSPYAAGQRLSAGVFVF
What is the function of this protein?
May act as an adapter to facilitate the interaction of SnRK1 complex with effector proteins, conferring tissue- and stimulus-type specific differences in the SnRK1 regulation pathway.
What are the official names of this protein?
FCS-Like Zinc finger 13.
What is the protein family that this protein belongs to?
Belongs to the FLZ family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles from the cytoplasm to the nucleus when associated with KIN10.
Protein: PNP_LAWIP
Sequence: MSFRKPPIRLATQVGGKEIIFETGYMATQANGSLTVQCGGTIVLVTVCSQPLESDKGFFPLTVEYSEKMYAAGRIPGSFFRREIGRPSERETLISRLIDRPIRPMFPKGLAEDVQILANVISSDQENESDILAVTGASAAVMLSSLPFECAIAAGRIGRLNGQFVLNPTINEIELSDLNIVFAASSEAVVMVEGEANVVEEEIIIEALEWGHKEIQPIITLQNKIQELAGRNKIPFVPVEENIVFSKKVEELADKFGIVEAMQVKEKQFRKEARKAVKEKVLAILKEDPLYAEHSDILNTVSEIIGNLEKKIVRQRIVKENLRIDGRDTITVRPIAIEVGLLPRTHGSALFTRGETQSLCITTLGSSTDNQRVDSLAGDTVKNFMLHYNFPPFSVGEVKPVRVSRREIGHGALAEKALKYILPSQNTFPFTVRIVAETLESNGSSSMAAICGGCLSLMDAGVPISAPVAGVAMGLIKEDDQFIVLTDIIGDEDAFGDMDFKIAGTTKGITAVQMDIKITGLTTDVMRKAMEQAREARIHILSEMAKALDVPRSNLSQYAPQHAELVVNPDAIRMIIGPGGKNIKQITTVTGAAIDINDSGKISIFAPTSEAMEQAKQMILYYDQRPELGKNYKGKVRKILEIGAILEIMPNVEAFVHISQLAVEHIAQVTDVVQLGEDMIIKVIEITGDRVRASRKAVLLEEEGITWTPEESSRFSKGNRNGDRSRHNNRERTRRT
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DSS1_CAEEL
Sequence: MSSTAAKKDVKSSAVPVTAVVEKKEFEEEEFEEFPVQEWAERAEGEEDDVNVWEDNWDDETHESEFSKQLKEELRKSGHQVA
What is the function of this protein?
Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis.  Has an essential role in oogenesis and larval growth.  Required for intestinal function and default lifespan.
What are the official names of this protein?
Probable 26S proteasome complex subunit dss-1, Deleted in split hand/split foot protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the DSS1/SEM1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Diffuse in cytoplasm.
Protein: GSA_FRACC
Sequence: MVVPSAAPASEELFRRAERVVPGGVNSPVRAFRAVGGTPRFMVAGNGPYLTDADGRTYIDLVCSWGPMILGHAHPAVVEAVSRAVSVGTSFGTPTPGEVELAELIVDRVGPVEKVRLVNSGTEATMSAVRLARGFTGRSTIIKFAGCYHGHVDALLASAGSGVATLGLPDTPGVTGAATADTIVLPYNDLALVEAVFVERGETIAAVITEAAAANMGVVPPLPGFNAGLRRLCDIHGALLILDEVMTGFRISRAGWWGNEGAIEDWSPDLFTFGKVMGGGLPAAAFGGRADVMARLAPAGPVYQAGTLSGNPIAVAAGLATLRACTDEVYATVDTRAADVAGIVSTALTEEGVAHLPSSAGSLFSFFFTDAATVVDYAGAQAQNTARYAAFFHSMLDAGIYLPPSAFEAWFVSAAHDDETVERIAAAAPAAARAAAAVPEPVTVSASPEGRA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM23_CLAL4
Sequence: MFRRALPAARNFGSQLRTTRTFSLSGALLAETKSSKTNRFASKYKKSSSGNKNGPRHDNAPKKFRQGDTRTKTIRFNFDSGSEKAKEALKDLIKRVHGYSPNYQVQFVDPQTNKLRKMHLVELVNSTDLDKDGLLMVGPSSAQEMPLVRTIRVQDMIKEYSDRLALAKEKELLASGSVIAQRVINKRMQAEKKKSATKMLALSWSISVSDLMHQKKNEILKRVDNNEKFIIFVGEKESLYSARNSVEKEDGIASQLGTSRTKWDRMDEDELAMEMKKREMIFGKLEELLAECECKYDVSGSLDARMMLNVTPKPNVSKASEKETEVSARELKRQRMLAKSREAAKAKKKIDEEDLDSLYSIKIIE
What are the official names of this protein?
Altered inheritance of mitochondria protein 23, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM23 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: AROE_SULIL
Sequence: MLEEINYDTKLFGLIGKNIKYTLSPYIHNFSFTTLGINAVYLVFDLDEMKFNRIINGLLEIAEGLNVTIPYKEEVMKYLDNTDTYSTRIQAVNTIYKKSGYNTDYLAIKNLVRKKIGNMSGYECYVYGAGGAAKAAAFALSELGCSSISIVNRTNLRANELVELLNKNGYNASIKENCNSTSNIVVVNSTPNPSVVPENCIQKSELVIEFVYKPVETELIKNAKKYGIKYIDGLEILVNQAVEAEKIWFNKSVSDEKIIEYLYARKLVW
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: RLMD_KLEP7
Sequence: MAQFYSAKRRVTTRQIITVTVNDLDPFGQGVARHQGKALFVSGVLPHEQAEVVLVEDKKQYARAEVKRRLTDSPQRQAPRCPHFGVCGGCQQQHASVPLQQQSKRAALGRLMKREVDDVIAGAPWGYRRRARLSLNYQPKTQQLQMGFRQANAKAIVDVVQCPVLVPQLEALLPAVRECLSALSALRHLGHVELVQADNGPLMVLRHTAALPATDREKLERFSQTHGLSLYLAPQSEILEHIHGEAPWYTSDGLRLVFSPRDFIQVNDGVNQQMVRTALEWLDLRPEDRVLDLFCGMGNFTLPLATRAAHVVGVEGVPALVEKGRENAARNGLSNVTFFHENLEEDVTRQAWAKHGFDKVLLDPARAGAPGVMPHIIKLAPRRVVYVSCNPATLARDSETLLQAGYQIQRLAMLDMFPHTGHLESMVLFERRLT
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: SPEA_VIBVU
Sequence: MRLDVEQTSKLDRVRADYNVHYWSQGFYGIDDQGEMYVSPRSDNAHQIQLSKIVKQLEERQLNVPVLVRFPQILHQRVHSICDAFNQAIEEYQYPNKYLLVYPIKVNQQREVVDEILASQAQLETKQLGLEAGSKPELLAVLAMAQHASSVIVCNGYKDREYIRLALIGEKLGHKVFIVLEKMSELDLVLREAKSLGVTPRLGIRIRLASQGAGKWQASGGEKSKFGLSASQVLNVISRLKKENQLDTLQLVHFHLGSQMANIRDVRNGVNESARFYCELRTLGANITYFDVGGGLAIDYDGTRSQSSNSMNYGLVEYARNIVNTVGDVCKDYKQPMPVIISESGRSLTAHHAVLISNVIGTETYKPETVTEPEEDFPLLLNNMWRSWLNLHNGTDARALIEIYNDTQSDLAEVHSQFATGVLTLEHRAWAEQTSLRIYYELNRLMSTKNRFHRPILDELSERLADKFFVNFSLFQSLPDSWGIDQVFPVLPLSGLQNAADRRAVMLDITCDSDGAIDAYVDGQGIESTLPVPAWNEDEPYLMGFFLVGAYQEILGDMHNLFGDTHSVVVNVGDQGEINIDFINEGDTVEDMMRYVHIDVDQIRKNYHSLVSQRVDQEEQQQILAELEQGLSGYTYLEDF
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: DSBB_STUS1
Sequence: MRLASPRSLFVIAFLGSALLIAIALYMEHVMGLAPCPLCIVQRICVIGFGLVCLVAAIHGPAKVGRRVYAAIAALFVAAGAATAIRQIWLQSVPADQLPSCLPSLEYMMEALPFQEIARLVLHGTAECAEVSWTMLGMSIPEWSLLGFIGMAIVCLWQLLRRD
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
Protein: ATPE_STRCO
Sequence: MAAELHVALVAADREVWSGEATLVVARTTSGDIGVMPGHQPLLGVLESGPVTIRTSDGGTVVAAVHGGFISFADNKLSLLAEVAELSDEIDVHRAERKLEQAKTEGDAHAERRADVRLRAAAGR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.