PharMolix/UniProtQA huggingface dataset:
Protein: PCARE_HUMAN
Sequence: MGCTPSHSDLVNSVAKSGIQFLKKPKAIRPGCQGGSERGSIPLLVKNSTCYDAGEGLAEEQPSPRRNQTTAKGLCQLMGDPASGKRKDMEGLIPGTKTSSSQLNKSQSHMAKDIPFKTQGSHGSQGADFSGDESEESSTQDTSKWKRTAKCHTSSTQSHCYQTIHPAHEPEGKVDFPEPLVKAHQQAYTYLHSSLSKYEAILCIIHQATQTRELLQPMVSFLLLCFEEISQLLGEISKDGEVLLQEVREDLAWPLKKREPQEQPNLLQQLLQYTVSKLQVLNGTVASLTGSFLEGSSSYLHSTATHLENKLSTKRNVDERLLRALRQLESLASGCGDPGVQGLPLCSEDSGIGADNESVQSVDKLGKQTSWDLAPEPEEWKSVTSPHTEARQSGHTWQQSPFCLGSGRPQDCLLSGAPMAKVQPRAQDEARSPCLSSTSPENITSPPLKLGTSTPCDSFGIGVSVEPHLSKTSRPMDASSLSDSEDSSPEEEEEDKMSSMSLCAWQEKTPHSRPQSSPADRESPFQARTRRLRSLQAQEMILKMKESISERIKFVPVPCGHQDWSEEEEGRTVVPPRPSTVSGSRRAPERQTRSQSESCLQSHVEDPTFQELRRVQRDLSQKLEAFYALGAKGQGQSQEQILQPRAAAVWPNGTCRVSPSNTTSRLKASLTKNFSILPSQDKSILQKCNPHPEDEQGKAGKLPNAIPSGEVSEAAKATDWNVRGCPTRTSVKKLIETFSPTESLRMLGDSKDAGASPCLRNCIMPPRFPKYTGLAPLYPKPQISPASGRESLKMGIGWKPLAPIFPPLPKAEAAKSEELSCEMEGNLEHLPPPPMEVLMDKSFASLESPESSKSTENSPKETQEPGPGEAGPTRRTWASPKLRASVSPLDLLPSKSTASLTKPHSTGPGSGRSSCQPRKPALDLSSPPATSQSPEVKGGTWSQAEKATSLYRQPRKAIAWHHSGPPSGQNRTSESSLARPRQSRERSPPVGRKASPTRTHWVPQADKRRRSLPSSYRPAQPSPSAVQTPPSPPVSPRVLSPPTTKRRTSPPHQPKLPNPPPESAPAQCKVPSPPTQHPEASPPFSIPSPSPPMSPSQEHKETRDSEDSQAVIAKVSGNTHSIFCPATSSLFEAKPPLSTAHPLTPPSLPPEAGGPLGNPAECWKNSSGPWLRADSQRRAALCALNPLPFLRRTASDRQPGGRPQPPTLDPTSTSYESQLGQNSSSEESPKKDTEPGSSPCSPELQGGTRRASPPEFCVLGHGLQPEPRTGHIQDKSQPEAQPQQEEVS
What is the function of this protein?
Plays an essential role for normal photoreceptor cell maintenance and vision.
What are the official names of this protein?
Photoreceptor cilium actin regulator.
What are the subcellular locations of this protein?
Cell projection, cilium, photoreceptor outer segment. Photoreceptor inner segment.
Protein: QID3_TRIHA
Sequence: MKFLTVAAVFFTAVLAAPGNYPPPPPPTYAPPPPTYTLPPNGNGGGNGNGNGNGNGGGNGNGNGNTNTGGSALCPAGLYSNPQSCATDVLGLADLDCAVPSTTPHDGPNFQSICVANGGKRARCCVLPVLGLGVLCQNPVGTN
What is the function of this protein?
Contributes to surface hydrophobicity, which is important for processes such as association of hyphae in reproductive structures, dispersal of aerial spores and adhesion of pathogens to host structures.
What are the official names of this protein?
Cell wall protein qid3.
What is the protein family that this protein belongs to?
Belongs to the cerato-ulmin hydrophobin family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: APO1A_PANTR
Sequence: MRLFLSLPVLVVVLSMVLEGPAPAQGAPEVSNPFDGLEELGKTLEDNTREFINRITQSELPAKMWDWFSETFRKVKEKLKIDS
What are the official names of this protein?
Apolipoprotein C-I, acidic form, Apo-CIA, ApoC-IA, Apolipoprotein C1A.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: VF169_ASFK5
Sequence: MNVDFIAGINNLGEKIYTCEPFKTSFQNPFIVALIITAVVLVVFFAICNPPVDKKRKTKTAIYIYICIVALLFLHYYVLNHQLNDIYNKSNMDVIVSSIHDKYKGGDEIIPPVSPPSVPDELEEDRPKMIPAGSKPADFKPAEPAVSKPLIPLQEVIMPSQYNN
What are the official names of this protein?
Transmembrane protein B169L, pB169L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus B169L family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein. Virion.
Protein: SYE_FRAT1
Sequence: MITTRFAPSPTGFLHVGGVRTALFSWLYAKNNNGKFILRIEDTDLERSTQEAVDAILDGMSWLGLKNDGEIYYQTKRFDRYKEVIQELIADGKAYYCSCSKERLEELREYQQANNLKTGYDGKCRDANYIPQQGESYVVRFKNPQDGVVSWDDAVKGRISISNHELDDMIIQRADGSPTYNFCVVVDDIDMAITHIIRGDDHVNNTPKQINIYKALNANVPIFAHVPMILGPDGAKLSKRHGAVNVMQYREDGYLPQAILNYLVRLGWSHGDQEIFSIEEMIKAFNLEHINASPSRFDFEKLKWLNKHYIKESKFDDIQTEVEYHFAKTGLDISNGPDLKELVAVMAEKVDTLVELAEKSSYFYSDDISYDENAVKKHIKASTGEIFVKLLENFEALDAQQWQDPDVLHNIVSTTAEQCQVGMGKVGMPLRVAITGSGQSPDIGITLKLLGKNKVVARLTKALEELCK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_BORBR
Sequence: MSSNTVAQFATELKMPANVLLEQLRAAGVDLKSVDDAVTDSDKAKLLESLRRAHGATEGKKITLTRRQTSEIRQADATGRSRTIQVEVRKKRVFVKRDPAELAAEQAAARAEEAAAEAVPAEAAPAPAEPVRAEPAVETAAKPVEPPVAEAPAEPVAAPAAEPQSEQPAQAEAQPEPTPAAQAEPEPQPEPQPEAAPAQAVAEPVEPAKNVSVTETEAEQARPEPVVHAQTELTSKTPAPVAQPSAPAESPKSAKAEPAAAPKTTAKPGEIRRAAAPAAPDRAREEARRAAEAEAAALREMLSRPRKVLRAPEPEPQAGALSGTLHKPAGKPATTAAPKKDAKPGAPGAKKTIKTAEVSSTWSDDSARKKPADNKPAVTTRDGWRAGGKGGRGGRNSRNQHQDRRHEQVQQEFIAREIHVPETISVADLAHKMSVKAAEVIKQLMKLGQMVTINQVLDQETAMIVVQEFGHMAIAAKLDDPEAFLDETAAVTEAEAEPRAPVVTVMGHVDHGKTSLLDYIRRAKVASGEAGGITQHIGAYHVETGRGVVTFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTREAIHHAKAGGVPLVVAVNKIDKPEANPERVKQELVAEEVVPEEYGGDVPFVPVSAKTGAGIDDLLENVLLQAEILELKAPIEAPAKGLVIEARLDKGRGPVATILVQSGTLKRGDVVLAGASFGRVRAMLDENGKQIQTAGPSIPVEIQGLTEVPAAGDELMVLSDERKAREIALFRQGKFRDVKLARQQAAKLESMFDNLGEGTQTLALIVKTDVQGSQEALVSSLTKLSTDEVRVQVVHAAVGGISESDVNLAIASNAVVIGFNVRAEQSAKKLAETNGIDLRYYNIIYDAVDEVKAAMSGMLAPEKREEVIGLVEVREVYTISRIGTVAGCMVLDGVVRRDSQVRLLRNNVVQWTGHLDSLRRFKDDVKEVKSGFDCGLTLRGNNDLQLGDQLEVFEIKEIARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1499_FRATF
Sequence: MNFDMSKLMQQAQKMQEQMKKAQQERENMEVIGESGAGLVTVTMTGKYDVKSVSIDNSLMSEDKEILEDLIAAAVNSAVKKVEENSTASSNIYKMAKDAGIDLPSGINFPFK
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein FTA_1499.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ECSA_BACSU
Sequence: MSLLSVKDLTGGYTRNPVLKNVSFTLEPNQIVGLIGLNGAGKSTTIRHIIGLMDPHKGSIELNGKTFAEDPEGYRSQFTYIPETPVLYEELTLMEHLELTAMAYGLSKETMEKRLPPLLKEFRMEKRLKWFPAHFSKGMKQKVMIMCAFLAEPALYIIDEPFLGLDPLAINALLERMNEAKKGGASVLMSTHILATAERYCDSFIILHNGEVRARGTLSELREQFGMKDAALDDLYLELTKEDAGHE
What is the function of this protein?
Has a role in exoprotein production, sporulation and competence.
What are the official names of this protein?
ABC-type transporter ATP-binding protein EcsA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: U2A2A_WHEAT
Sequence: MAEHDAPPESGAARSPPAKKRGGDARSPQQDAQPLSSRDRVRERDEDKDRERHRRHGEDRERYRDRESVRERGEGSRDRERHRREHREESRDRERHHREHREGSRDRERHHREHREGSRDRERHHREHREGSRDRERHHRDHREGSRDRERHHRDHRERSERREHRDRSDDRDYRRSCDRDAERRDRDRDGHRRHRSRSPLRSESQSKRMSGFDQRPSEAIPILAPDATPSQLPELPAANPGMFPNMLPNLVNVPALGQPLAMTQQATRHARRVYVGGLPPIANEQTVAVFFNQVMAAIGGNTFALGHAVVNVYINHDKKFAFVEMRSVEEASNAMALDGIMFEGAPVKVRRPTDYNPSQAAALGPSQPNPNLNLAAVGLTPGAGGGLEGPDRIFVGGLPYYFTEAQVRELLETFGPLRGFDIVKDKETGNSKGYAFCLYKDGTVTDIACAALNGIQLGDRTLTVRRANQGAEPRPEQENILLQAQQEAQMKRLVYEVGRTLTTKVVCLTQVVSADDLRDDEEYNDILEDMTLEGHKYVPHSTIAESFIIRPHAKFAIRPKLTEDTNLFHLDLTNHMFSSLPFCHVHVCSY
What is the function of this protein?
Necessary for the splicing of pre-mRNA.
What are the official names of this protein?
Splicing factor U2af large subunit A, U2 auxiliary factor 65 kDa subunit A, U2 small nuclear ribonucleoprotein auxiliary factor large subunit A, U2 snRNP auxiliary factor large subunit A.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DCL22_ASPNC
Sequence: MTSSTDYHADSTPGTTSNMELRIREYQLEMLNESLKRNLIVVMPTGTGKTQVAILRILADIDKGNSDKFVWLLCPTVALSEQQYIQYATVFLPSGAEDKAIWDNALSGIKIAVSTYQVLYDALSHGFVKLSQMSLLIFDEAHHCKKDHVANKIMQVHYHKQHQSGVQNLPKILGLTASPILSDLSSLEIVESNLGSICKTPRQYYAQLLQFTNRPLILPRLPTYTIPNCSVKAPILEKLCGILSSEDEVPSSSKMKSKQLKHIRRFMQTSESINQELGIWAATEYMRKSIMHFKESMRMGAEKTNISNYGKDFAMEILTRLGKLQDCSPAIQPEEISPMCQCLLDELSKAYREGFCGLVFVTQRATVLALKWLIENHPLTSHLFTCGTFIGMSTTQYSKTELGNLHDIRNQTETLEKFRQGSLNLIITTDALEEGIDVPACNTVLNFNCQLSLKSFIQRRGRARRENSQFIIIMEDESGPRYLKRLEMEEIELVQKLQNAERRQIPANELDFDKYERISLSLDIDRTGAQLIMREAVGYLYNFCSKLPAQLYVSNKPLFTYERNNYGRFRAVVKLPSNLDPSLQSFSSSRSWSRLKYAREDAALQAYKALYQAGLVNDYLVPTQVSDHLEGDIIFRSHYSIQNQLDPWQDIALLWKLDSQLYAHNLRIIRPEEDEIHLHMILPTQLDTTIHIPLFIDYCTTYTAILTPGHPITTDISLCQQVTNLIFQSVYRDHCSRRNLDYAFLLVPELEETKLIEFLERYSGSVSLTELLNQEATPSALGLLRSHTRPSRPLLVEPWVAGECFLPDELSISSFDAKVKYMTNRRNFLSHGNLAAGKSTNCEARIGLEANVKSMSVRDFFVDKLPSMFAQVALFTPSISHEVEVYMIAQILRQELSLRSVTPWQRIDLLAIAIRPTSIEHRATFRLLAFIGDAFMKYLFAMQLFLHHHLWHEGLLSSLKQRNLSDAGLAHAIHQSGLGKFLISKHLNGKRWVPPLVSGIEPASNEARQRSIGAATLADMTKAVVGAAFTDGGLNQAAACASVMFPKLKSWNASSLHDGTYSKTRPENAVASTAIVDMEELLGYTFTDKSLAVESMTHPSCTGLVQTTSYRRLSFLGASVLEWIVVSYLHRHAQVMNPQRMQSLKSAFTNNTFLTFIAITFHQVREQNHIDVDDEHNVHKNVTTCSIRLWDFLRLHSDALSTELSDFVQKSSEKADAIKHELWEQRFYPWVRLRALGDMRVLSDIIQSIFGAVFIDSQATLASCDALAEKLGIVPLLEHFISHQITTDHPKDTLQAILPGRKVSYQICVDKVHPGTLRCSALADSSEIASVEGQMNDEVIKMQAAETAVRLLRKGFALSETS
What is the function of this protein?
Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway.  Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS).  Part of a broad host defense response against viral infection and transposons (By similarity).
What are the official names of this protein?
Dicer-like protein 2-2.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Dicer subfamily.
Protein: BGL15_ORYSJ
Sequence: MARRRMGEEGKGGGWGLNGRQCRFGNRLRAVKGEGWRSAVAAQAATGRREEDDAGGREKGEKRERKGGLSPCLFGKRRRERRRGGRGRREALPPSLGGLRAERRGRGDDDVLINYNVQHVSRIKLEERLLITDKLSLRFLDPIFFGEYPREMREILSSNLPKFTPEEKKLLQNKVDFIGINQYTAIYAKDCIYSPCALNTYEGNALVYTTGVRNGAKIGKPTAFSTYFVVPESIESAVMYVNGRYKDTTIYITENGYSQHSDTNMEDLINDVERVNYLQGYLKYLSSAVRKGANVGGYFMWSLIDNFEWVFGYTIKFGLYHVDFDTQERIPKMSAKWYRDFLTGSNVTDDTQVWSRRADS
What are the official names of this protein?
Putative beta-glucosidase 15, Os4bglu15.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: SECA_NEIG1
Sequence: MLTNIAKKIFGSRNDRLLKQYRKSVARINALEEQMQALSDADLQAKTAEFKQRLADGQTLDGILPEAFAVCREASRRVLGMRHFDVQLIGGMVLHDGKIAEMRTGEGKTLVATLAVYLNALAGKGVHVVTVNDYLASRDAGIMEPLYNFLGLTVGVIISDMQPFDRQNAYAADITYGTNNEFGFDYLRDNMVTDQYDKVQRELNFAVVDEVDSILIDEARTPLIISGQADDNIQLYQIMNTVPPHLVRQETEEGEGDYWVDEKAHQVILSETGHEHAEQILTQMGLLAENDSLYSAANISLMHHLMAALRAHSLFHKDQHYVIQDGEIVIVDEFTGRLMSGRRWSEGLHQAVEAKEGVEIKRENQTLASITFQNYFRLYTKLSGMTGTADTEAFEFQSIYNLETVIIPTNRPVQRKDLNDQIFRSAEEKFEAVVKDIEECHKRGQPVLVGTTSIENSELVSRLLQKAGLPHNVLNAKEHEREALIVAQAGKVGAITVATNMAGRGTDIVLGGNLKHQTDAIRADETLSDEEKQAQIAALENGWQAEHDKVMEAGGLHIIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSFEDPLLRLFALDRAAAILNRLAPERGVAIEHNLLTRQIEGAQRKVEGRNFDMRKQVLEYDDVANEQRKVIYSQRNEILTSKDIGDLMQEIRSDAVSDLVDTYMPPDSMEEQWDIPTLENRLAAEFRLQEDIQSWLKADNAIDGQDIKERLIERIENEYAAKTELVGKQAMADFERNVMLQAIDNQWREHLAAMDYLRQGIHLRSYAQKNPKQEYKREAFTMFQDLWNGIKFHIASLLTSVQIEQNPVAAVEEQPVGNIQSIHSESPDIEELLGQSQTDLVTEAFNPDGTDFSPEALEARGQIVHRNDPCPCGSGLKYKQCHGKLA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: THIG_HELMI
Sequence: MDRLVIGGRELKNRLFIGSGKFADERVIRDIVAQTGVEVVTVALRRVSLSGDGENILHCIPKECVLLPNTSGARTAEEAIRIARLARAAGCGNWVKIEVISDNKYLLPDNNETIKATGVLAEEGFVVLPYMHPDLYAAKELERAGAAAVMPLGAPIGTNRGLKTKEIVRILIEECSVPVIVDAGIGKPSEAAEAMEMGAAACLVNTAIATAGDPLVMARAFSQAVAAGRLAYLAQPGERTEYARASSPLTGFLGS
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABA_XYLFM
Sequence: MSRQHAYSREELLATARGELFSHSNARLPNDPMLMFDRITGIYADGGSHGKGIVNAELDIRPDLWFFGCHFLGDPVMPGCLGLDAMWQLTGFFLTWSGATPGYGRALGCGEVKFTGQVLPNAKLVRYEVEMTKIINRTLVIGQANARMLVDNREIYFAKDLRVGMFNNTESF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELD_TREDE
Sequence: MSCSLINEDFDLLKAAKNPGUGAKLSAGALDKLLKNFSVRNDDNLLVGFNTSDDAAVYKINDKTALISTIDFFPPVSGDPYIFGQVAAANSLSDIYAMGGEPKLALNLFCITKDMPEDMIKEILRGGFDKVYEAGAIVCGGHTIYDDSPKYGLAVNGFVHPKKILENSTAKEGDVLILTKPIGTGILLTASKADMSPPEELDRCYKIMAFLNAKARNIMVKYKINACTDITGFGLLGHLYEMGKGSGMSIEVDYKSVPIYKSVIESAEMGMMPAGVYSNRNFVGDNIVFENVPLAYQDLMFDPQTSGGLLISVDKEDAAALYEELSQALENTPCGKPAIIGLVTKRDEKILRVS
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: RS8_SERP5
Sequence: MSMQDPIADMLTRIRNGQAANKVAVTMPSSKLKVAIANLLKEEGFIEDFKIEGDTKPVLELVLKYFQGKAVVESIQRISRPGLRIYKKKDALPKVMAGLGIAVISTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: ASLA_ECOLI
Sequence: MEFSFSPKRLVVAVAAALPLMASAADTPSTATARKGFAGYDHPNQYLVKPATTIADNMMPVMQHPAQDKETQQKLAELEKKTGKKPNVVVFLLDDVGWMDVGFNGGGVAVGNPTPDIDAVASQGLILTSAYSQPSSSPTRATILTGQYSIHHGILMPPMYGQPGGLQGLTTLPQLLHDQGYVTQAIGKWHMGENKESQPQNVGFDDFRGFNSVSDMYTEWRDVHVNPEVALSPDRSEYIKQLPFSKDDVHAVRGGEQQAIADITPKYMEDLDQRWMDYGVKFLDKMAKSDKPFFLYYGTRGCHFDNYPNAKYAGSSPARTSYGDCMVEMNDVFANLYKTLEKNGQLDNTLIVFTSDNGPEAEVPPHGRTPFRGAKGSTWEGGVRVPTFVYWKGMIQPRKSDGIVDLADLFPTALDLAGHPGAKVANLVPKTTFIDGVDQTSFFLGTNGQSNRKAEHYFLNGKLAAVRMDEFKYHVLIQQPYAYTQSGYQGGFTGTVMQTAGSSVFNLYTDPQESDSIGVRHIPMGVPLQTEMHAYMEILKKYPPRAQIKSD
What is the function of this protein?
No E. coli strains have been observed to have an arylsulfatase activity.  A 'latent' activity has been observed by heterologous expression of a genomic region linked to tynA, but it does not map near aslA.
What are the official names of this protein?
Putative sulfatase AslA.
What is the protein family that this protein belongs to?
Belongs to the sulfatase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RIBA_HAEI8
Sequence: MAKIQLVAQANLPTEYGIFKMVGFEFPDTKKEHVALVMGDISNADEPVLARIHSECLTGDALHSLKCDCGFQLATALKQIQEEGRGVLIYHREEGRGIGLINKIRAYSLQDKGMDTIEANLALGFKADERNFEVCADMFELLGVKKVRLMTNNPEKVETMKKAGINVVERVPLNVGENRYNTKYLDTKAKKMGHYIVHNNDEQHLMTCPHCQEEII
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: IMP05_NAUMA
Sequence: LGSLDEYAR
What are the official names of this protein?
Uncharacterized protein IMPP5.
Protein: CRCB3_BRUSU
Sequence: MSVEASILVLVGGFIGGVMRFFLSGYVGRRIGETFPWGTFVVNVSGAFVIGTAAGLGARLGAIFSTTIFHEFIMVGLLGGYTTVSSFCLQSVNLMLDGEQRQALFNIVASALLCVLAVAAGYGGIMWIMEWPG
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 3.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VPS20_YEAST
Sequence: MGQKSSKVHITKTDRAILEVKRSKDEIHKFTRRTDNLILVEKSQLKDLIRKNPENYKSNMKVRFLLKRIHYQEHLLQQASDQLINLENMVSTLEFKMVEKQFINGLKNGNEILKKLNKEFSNVDELMDDVQDQIAYQNEINETLSRSLVGTSNYEDDLDKELDALESELNPEKMNNAKVANMPSTEGLPSLPQGEQTEQKEREEFATEERSDTKEPLALLS
What is the function of this protein?
Class E VPS protein implicated in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles.  The lumenal sequestrated membrane proteins will be targeted into the vacuole after fusion of the endosome with the vacuole.  Acts a component of the ESCRT-III complex, which appears to be critical for late steps in MVB sorting, such as membrane invagination and final cargo sorting and recruitment of late-acting components of the sorting machinery.  The MVB pathway requires the sequential function of ESCRT-O, -I,-II and -III complex assemblies.  Required for the oligomerization of SNF7 into a membrane-associated filament.  The VPS20-SNF7 subcomplex is responsible for the membrane association of the ESCRT-III complex.  Also required for the RIM101 repressor proteolytic activation.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 20, Amino acid sensor-independent protein 10, Charged multivesicular body protein 6, ESCRT-III complex subunit VPS20, Vacuolar protein-targeting protein 20.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Protein: ILVD_SHEON
Sequence: MPKLRSATSTEGRNMAGARALWRATGVKDNDFGKPIIAIANSFTQFVPGHVHLKDMGSLVASAIEEAGGIAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADALVCISNCDKITPGMLMAALRLNIPVVFVSGGPMEAGKTKLSDKLIKLDLVDAMVAAADSSVSDEDSAKIERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSMLATHSDRRELFLEAGRRVMALTKRYYEQDDTSALPRNIACFKAFENATALDIAMGGSSNTVLHLLAAAQEAEVAFTMDDIDRMSRLVPHLCKVAPSTPKYHMEDVHRAGGVMGILGELDRAGLLHTDVPHVAADAGGNLKSVLAKYDVMQTQDDNVKQFFMAGPAGIPTTKAFSQDCRWPSLDDDRREGCIRSREFAFSQEGGLAVLSGNLAENGCIVKTAGVDESNLIFVGSARVYESQDDAVAGILGGEVVAGDVVVIRYEGPKGGPGMQEMLYPTSYLKSRGLGKACALITDGRFSGGTSGLSIGHVSPEAAAGGTIALIENGDRIEIDIPARSIKLAVSDAELAGRRETMLARGPMAWKPVGRERFVSMALKAYAMLATSADKGAVRDRSKLED
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: SYD_ERWT9
Sequence: MRTEYCGQINLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRQEAFTLASELRNEFCIQIVGTVRARDEKNKNGDMATGEIEIFATELTIINRSEPLPLDSNHINSEEARLKYRYLDLRRPDMANRLKTRAKITSFVRRFMDDQGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAPQVREVMERLVRELWQDVKSVDLGAFPSMTFAEAMRRYGSDKPDLRNPMELVDVADLLKNVEFKVFSGPANDVKGRVAALRVPGGAALSRKQIDDYAKFIETYGAKGLAYIKVNERAKGIEGITSPVAKFLNAEIVESILQRTAAADGDLIFFGADSAKVVADALGALRLKLGRDLNITNGSVWAPLWVLDFPMFEDDGEDGLTAMHHPFTAPKEMSPEQLKNAPETAIANAYDMVINGYEVGGGSVRIHNGQMQQTVFGILGITEQEQREKFGFLLDALKFGTPPHAGLAFGLDRLVMLLTGTDNIRDVIAFPKTTAAACLMTEAPNFANPASLTELGIEVVKKAKDRPSEND
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_RALSO
Sequence: MASKGGRDKIKLESTAGTGHFYTTTKNKRTKPEKMEIMKFDPVARKHVAYKETKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: HIS6_DEHMC
Sequence: MLNKRVIPCLDVNNGRVVKGTSFVNLRDAGDPVELAARYYREGADELVFLDISATTEERKTMAEVVEKVSKEVFIPLCVGGGLRSIADMTTLLRAGADKVSVNSAAVSDPDLISRGAEKFGRQCIVVAIDAKREGNSWQVYTHSGKKPTGLDAVEWAMKAEQLGAGEILLTSIDADGKNTGYDNELNREVGSRLNIPVIASGGAGSPEDLYNALDKGQADAVLAASIFHYGRYSIAEVKKYLKSKGLPVRLEN
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.