PharMolix/UniProtQA huggingface dataset:
Protein: RL31_GEOSM
Sequence: MKEGIHPKYNEIIVKCLCGNSFESRSTKAEISTEVCSQCHPFYTGKQKLMDTAGRVERFRKRYNIAAAPEES
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: THIG_PROMH
Sequence: MLKIADTTFTSRLFTGTGKFATPTLMAEAIKASGSQLVTMAMKRVDLKNGNDDLIAPLKSLGIKLLPNTSGAKTAQEAVFAARLAKEAFDTHWIKLEIHPDTKYLLPDPIETLKAAELLVKEGFVVLPYCSADPVLCRRLEEVGCAAVMPLGSPIGSNQGLQTRDFLRIIIEQTSIPVVVDAGIGAPSHALEALELGADAVLVNTAIAVAKNPVLMAQAFKAAIDAGELARQSGLAVPTSITHMQAQASSPLTQYLEAF
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_CALS4
Sequence: MAISKSEVEYIAKLARLKFTEEEIEAMAQELSKILDYVNKLNELDTENVEPTAHIVPIHNVFREDEVKPSMPREKVLMNAPFTEQGCFKVPKIIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: OPSD_NEOAU
Sequence: TEGPDFYIPMVNTSGLVRSPYEYPQYYLVNPAAFAFLGAYMFFLIIIGFPVNFLTLYVTLEHKKLRTPLNYILLNLAVSDLFMVIGGFTTTMYSSMHGYFVLGRLGCNIEGFFATLGGMISLWSLAVLAIERWVVVCKPISNFRFGENHAIMGVSMTWLLALSCTVPPLVGWSRYIPEGMQCACGIDYYTRAEGYNNESFVIYMFTCHFSVPLFIIFFCYGRLLCAVKEAAAAQQESETTQRAEREVTRMVVIMVIGFLVCWLPYASVAWFIFTHQGSEFGPLFMAIPSFFAKSSSIYNPVIYICMNKQFRQCMITTLFCGKNPFEGEEEGSSTKTEASSASSVSPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: SIGA_STAAS
Sequence: MSDNTVKIKKQTIDPTLTLEDVKKQLIEKGKKEGHLSHEEIAEKLQNFDIDSDQMDDFFDQLNDNDISLVNEKDSSDTDEKLNPSDLSAPPGVKINDPVRMYLKEIGRVNLLSAQEEIELAKRIEQGDEVAKSRLAEANLRLVVSIAKRYVGRGMLFLDLIQEGNMGLIKAVEKFDFNKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINKLIRVQRQLLQDLGRDPAPEEIGEEMDLPAEKVREILKIAQEPVSLETPIGEEDDSHLGDFIEDQEAQSPSDHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVGKVFGVTRERIRQIEAKALRKLRHPSRSKRLKDFMD
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is the primary sigma factor during exponential growth.
What are the official names of this protein?
RNA polymerase sigma factor SigA.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMX3_MOUSE
Sequence: MANAVGRRSWAALRLCAAVILLDLAVCKGFVEDLNESFKDNRKDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFDHVRKRHRVFFVYIGGESPLKEKYIDAASELIVYTYFFSASEDVVPEYVTLKEMPAVLVFKDDTYFVYDEYEDGDLSSWISRERFQNYLTMDGFLLYELGDTGKLVAIAVIDEKNTSLEHTRLKSIIQEVARDFRDHFHRDFQFGHMDGNDYINTLLMDELTVPTIVVLNTSNQQYFLLDRHIKDASDMVQFINSILDGTVPAQGGDSIFQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYEVSKSEMENQEQIEESKEQESSSGGSLAPTVQEPKDVLEKKKD
What is the function of this protein?
Probable disulfide isomerase, which participates in the folding of proteins containing disulfide bonds.  May act as a dithiol oxidase (By similarity).
What are the official names of this protein?
Protein disulfide-isomerase TMX3, Thioredoxin domain-containing protein 10, Thioredoxin-related transmembrane protein 3.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: ARGB_ENDTX
Sequence: MSELTVVKFGGSLTENPQAQNKFLEELTLISKRQNIILVHGGGPEINALLEKFAITSRFVNGLRFTDADTLGVVELALSGKVNRVLTTGLIKNGANAVGISGKDGKSVICRQVEYLGFVGEPVKVNRKLIDILIKSRFLPVIASIAADVEGNIMNVNADTLAASIAVAFKAQKLIFLTDVAGVFDKNNNIIKEIKIKEINSLIEDKTITGGMIPKIKGCAESVKKGLKEVWIAEGISGIQKIKGTVIKK
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSD_YERE8
Sequence: MLNRLESLTQRVGGSNELIDQWLHARKELLVSYCTVIGIKPQKGKHTPLNEKALENFCHNLVDYLSSGHFHIYDRIIKQVEGASSPKMALTTKVYPALKNNTQTIMAFHDRYTNIEIDDDSCTEFQQALSDIGEALDARFRLEDQLIQWAAESWQAAKPVIQAGQVK
What is the function of this protein?
Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA.  May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
What are the official names of this protein?
Regulator of sigma D.
What is the protein family that this protein belongs to?
Belongs to the Rsd/AlgQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIM8A_XENLA
Sequence: MSDFDSNLDLAGTGASPAEAAELQRMLAVEQQKAQFTAQVHNFMDVCWDKCIDRPGNKLDSRTESCLVSCVDRFIDTTLSITNRFAQIVQKGAH
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane.  Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.  The TIMM8-TIMM13 complex mediates the import of some proteins while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim8 A.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: RPOB_ECO55
Sequence: MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: PPE29_MYCTU
Sequence: MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPSSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLIATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGAQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTFLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEFALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPIAATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPAMDD
What is the function of this protein?
Could be required for host endothelial-cell invasion and/or intracellular survival.
What are the official names of this protein?
Uncharacterized PPE family protein PPE29.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
Protein: SKA3_XENLA
Sequence: MSVTGNFFSKLRSLALTLEKETAQLEQVFGNEDNEYEEESPMRVLHDLRSDIMVLKGDFQSTLDKKLTRGQELSAFIKACRVLHERSAADIEQIKETFQTYGYKPLCNDNSENEQTQESEKPKDNDVSPRKADAEDLPILEKAASTSWDLLRAPQLSDFGLSHYQLPTAWEPPKVKPCPKNPEEEKPRIMYKDPEPINVAKTPKCALRLEEDFSQIQHFGISDCSTNLNDDYTIALINKNFQKKQNDTENETCQAKNLKSLLATPSHLSHRMDCVDSPLPPVFFTPGLKVHKKETISLPGKTGERQGLNAADTDSTLLSGTCDRKDSDNAHLEDVHECTAMKPAMDLKSISAAPPYLSLGSNFDSVYSPRPPVFCTPGLKTHKKETSSVLVEPKEVTGCSDTPPLPSFQTNWLKNDTTEKALDITEPVPRPELSYRQYLEEPPSLVLNSNKYEAPAMTEYDIGTPTRPEMTVSLTEDLFKYNVKPSSPPKMSEYEKMLWTPIRPEMTSCITEDISQILSKYCDNNTNVADKEMWNKAGASFGKISSEYEDKENRQY
What is the function of this protein?
Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.  The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies.  The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner.  In the complex, it mediates the microtubule-stimulated oligomerization.  Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules.
What are the official names of this protein?
Spindle and kinetochore-associated protein 3.
What is the protein family that this protein belongs to?
Belongs to the SKA3 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Localizes to the outer kinetochore and spindle microtubules during mitosis in a NDC80 complex-dependent manner.
Protein: CALCR_RAT
Sequence: MRFLLLNRFTLLLLLLVSPTPVLQAPTNLTDSGLDQEPFLYLVGRKKLLDAQYKCYDRIQQLPPYEGEGPYCNRTWDGWMCWDDTPAGVMSYQHCPDYFPDFDPTEKVSKYCDENGEWFRHPDSNRTWSNYTLCNAFTPDKLHNAYVLYYLALVGHSMSIAALIASMGIFLFFKNLSCQRVTLHKNMFLTYILNSIIIIIHLVEVVPNGDLVRRDPMHIFHHNTYMWTMQWELSPPLPLSAHEGKMDPHDSEVISCKILHFFHQYMMACNYFWMLCEGIYLHTLIVMAVFTEDQRLRWYYLLGWGFPIVPTIIHAITRAVYYNDNCWLSTETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRQTHEAEAYMYLKAVKATMVLVPLLGIQFVVFPWRPSNKVLGKIYDYLMHSLIHFQGFFVATIYCFCNHEVQVTLKRQWAQFKIQWSHRWGRRRRPTNRVVSAPRAVAFAEPGGLPIYICHQEPRNPPVSNNEGEEGTEMIPMNVIQQDSSA
What is the function of this protein?
This is a receptor for calcitonin.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.  The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin.
What are the official names of this protein?
Calcitonin receptor, CT-R, C1A/C1B.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PETG_ORYSA
Sequence: MIEVFLFGIVLGLIPITLAGLFVTAYLQYRRGDQLDL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ARGC_CLONN
Sequence: MIKVGIIGSTGYIGQQLVWLLKIHPNVEIVFLSSYNYAGYSFNSVYNNYKGFVETTCINIKEVKTRLKDVDIVFMALPHGKSFEMVKYSLNLGIKVIDLSGDFRLKDSKEYEKWYKIEHPLKEVLKYSVYGLPELFRKDIKKASLICNPGCYATASILALAPLIKLDLVEKGSIIVDAKSGVSGAGRALKTQSLYCECNETMKAYGIGNHRHTPEIEQELSRFCKEDIKLTFTPHLVPINRGIFATCYATLKKDLNKVQLEEAYEKFYENDYFIKVMKELVEVKWIKNSNFCNMNVNIDERTNKVIVSSVIDNLMKGAASQAVQNMNILFGIDEKTGLNIPSMMI
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CC50A_BOVIN
Sequence: MAMNYNAKDEVDGGPPCPPGGTAKTRRPDNTAFKQQRLPAWQPILTAGTVLPTFFIIGLIFIPIGIGIFVTSNNIREIEIDYTGTDPSSPCNKCLSPNVTPCVCTINFTLEQSFEGNVFMYYGLSNFYQNHRRYVKSRDDGQLNGDPSALLNPSKECEPYRRNEDKPIAPCGAIANSMFNDTLELFQVGNASDLTPIPLKKKGIAWWTDKNVKFRNPPGTDPLEERFKGTTKPVNWVKPVYMLDSDEDNNGFINEDFIVWMRTAALPTFRKLYRLIERKNDLHPTLPAGRYYLNITYNYPVHSFDGRKRMILSTISWMGGKNPFLGIAYITIGSISFLLGVVLLVINHKYRNSSNTADITI
What is the function of this protein?
Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids.  Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules.  The beta subunit may assist in binding of the phospholipid substrate.  Required for the proper folding, assembly and ER to Golgi exit of the ATP8A2:TMEM30A flippase complex.  ATP8A2:TMEM30A may be involved in regulation of neurite outgrowth, and, reconstituted to liposomes, predomiminantly transports phosphatidylserine (PS) and to a lesser extent phosphatidylethanolamine (PE).  The ATP8A1:TMEM30A flippase complex seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane.  Required for the formation of the ATP8A2, ATP8B1 and ATP8B2 P-type ATPAse intermediate phosphoenzymes.  Involved in uptake of platelet-activating factor (PAF).  Can also mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2, ATP8B4, ATP10A, ATP10B, ATP10D, ATP11A, ATP11B and ATP11C from the ER to other membrane localizations.
What are the official names of this protein?
Cell cycle control protein 50A, P4-ATPase flippase complex beta subunit TMEM30A, Transmembrane protein 30A.
What is the protein family that this protein belongs to?
Belongs to the CDC50/LEM3 family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Golgi apparatus. Cytoplasmic vesicle, secretory vesicle membrane. Apical cell membrane. Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment.
Protein: ILVC_CAMJ8
Sequence: MAITVYYDKDCDLNLIKSKKVAIIGFGSQGHAHAMNLRDNGVNVTIGLREGSVSAVKAKNAGFEVMSVSEASKTADVVMILAPDEIQADIFNIEIKPNLSEGKAIAFAHGFNIHYGQIVAPKGIDVIMIAPKAPGHTVRNEFTLGGGTPCLIAIHQDESKNAKNLALSYASAIGGGRTGIIETTFKAETETDLFGEQAVLCGGLSALIQAGFETLVEAGYEPEMAYFECLHEMKLIVDLIYQGGIADMRYSISNTAEYGDYITGPKIITEETKKAMKGVLKDIQNGVFAKDFILERRAGFARMHAERKNMNDSLIEKTGRNLRAMMPWISAKKLVDKDKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: APX1_ARATH
Sequence: MTKNYPTVSEDYKKAVEKCRRKLRGLIAEKNCAPIMVRLAWHSAGTFDCQSRTGGPFGTMRFDAEQAHGANSGIHIALRLLDPIREQFPTISFADFHQLAGVVAVEVTGGPDIPFHPGREDKPQPPPEGRLPDATKGCDHLRDVFAKQMGLSDKDIVALSGAHTLGRCHKDRSGFEGAWTSNPLIFDNSYFKELLSGEKEGLLQLVSDKALLDDPVFRPLVEKYAADEDAFFADYAEAHMKLSELGFADA
What is the function of this protein?
Plays a key role in hydrogen peroxide removal.  Constitutes a central component of the reactive oxygen gene network.
What are the official names of this protein?
L-ascorbate peroxidase 1, cytosolic, AP, AtAPx01.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Ascorbate peroxidase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FETP_ACIAD
Sequence: MTRLVFCRKYQQEMEGLDFAPFPGAKGQEFFDNVSKQAWQEWLQHQTTLINEKRLNVFEPEAKKFLEEQREKFFNNDASVEKAEGWKPEA
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: THIM_LACLA
Sequence: MSILEKIQEKQPLILNLANFVTPQRVADAISFAGGSPLMTAEISESETLVEIADAVVVNIGTISEKDYPLFLTICQLANQKHKPLILDPVAVNVPFRANFVKRLMQEVKFDIIRGNSAEIAWFADKESLNKGIDALESNLEVEHARVAAQKTGAVIIQTGKVDVISNGFEELFVETDSPLFKINVGCGDMLSAIVGTFAAVSDDLFKAAYEATEFFGESGVKATEQVENLPGNFVNRFLDKIYQATQEVI
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: ALL2_DERPT
Sequence: MMYKILCLSLLVAAVARDQVDVKDCANHEIKKVLVPGCHGSEPCIIHRGKPFQLEAVFEANQNTKTAKIEIKASIDGLEVDVPGIDPNACHYMKCPLVKGQQYDIKYTWNVPKIAPKSENVVVTVKVMGDDGVLACAIATHAKIRD
What are the official names of this protein?
Mite group 2 allergen Der p 2, Allergen Der p II, DPX.
What is the protein family that this protein belongs to?
Belongs to the NPC2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MFNB_METKA
Sequence: MRPRLLVSPVNRDEALEAVEGGAHIIDVKNPEEGSLGANFPWVIREIMEVVPEDREVSATVGDVPYKPGTVAQAVLGVAAVGVDYAKVGLYGTKTEEEALEVMRACSRAVREFGYDTRVVAAGYADAHRVGSLDPMSVPEVAAEAECDVAMVDTAVKDGKRLFDFLSEEEVGEFVDSAHEHGLEVALAGSLRHEDMPIVRDLGADIVGVRGAACERGDRNRGAIRSHLVRKLAEALA
What is the function of this protein?
Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).
What are the official names of this protein?
(5-formylfuran-3-yl)methyl phosphate synthase, 4-(hydroxymethyl)-2-furancarboxaldehyde-phosphate synthase, 4-HFC-P synthase.
What is the protein family that this protein belongs to?
Belongs to the MfnB family.
Protein: CYB_NYCLA
Sequence: MTNIRKSHPLIKIVNDAFIDLPAPSNISSWWNFGSLLGVCLIVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWLLRYLHANGASMFFICLYLHIGRGLYYGSYTYTETWNVGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLFAIPYIGTELVQWIWGGLSVDKATLT
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PT130_YEAST
Sequence: MKIFSTLLSQKPKGKLVIRPSTTIHSSDPFSKFIVTKNTEPLSLGDLRKSDSGNSAVCLNAENTILSTLTDLQKEEERNWDPVKFVAGKLRGVISPIQAYVTIGKKFSPNSLVYTSRFFQLHYFPEDHFMSCFRKSKPAITVKSNKKFYLNGKVFNKDKEYFNETRISKANEVELSKIQTAMTRLTNRHRNSIPSEFAYLRRDLKLKVKTTFIKEWCKLNGDKAIREYVNLNRSPNINPASMKGKPKKSFLDNLGRSTVGTAKDGYYLYIVSIFPDKDMLGEFNDEVNRSVQKVANLDWDGFLTPKKGTKGKNWVESFNDSINVQTINKILEINKFPFELRREQTEG
What are the official names of this protein?
Protein PET130.
What are the subcellular locations of this protein?
Mitochondrion matrix.