PharMolix/UniProtQA huggingface dataset:
Protein: RS8_BORPD
Sequence: MSMSDPIADMLTRIRNAQQVDKVTVSMPSSKLKAAIAAVLQDEGYIDGFEVKGTQAKPELEITLKYYAGRPVIERIERVSRPGLRIYKGRSNIPQVMNGLGVAIVSTSRGVMTDRKARANGVGGEVLCYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: CHLB_STAPU
Sequence: MKIAYWMYAGPAHIGTLRVASSFKNVHAIMHAPLGDDYFNVMRSMLERERDFTPVTASIVDRHVLARGSQEKVVENITRKDKEERPDLIVLTPTCTSSILQEDLQNFVDRAAMTSQSDVILADVNHYRVNELQAADRTLEQVVRYYLDKAHRQENLNQPITEVPSVNIIGMFTLGFHNQHDCRELKRLFQDLGIKVNEVIPEGGSVENLRNLPKAWLNIVPYREVGLMTALYLEKEFGMPYVATTPMGIVDTAKFIREIQHHINKWAPILLGKVVDYEEYIDQQTRFVSQAAWFSRSIDCQNLTGKKAVVFGDTTHAAAMTKILAREMGVYVVCAGTYCKHDAEWFKDQVQGFCDEVLITDDHTEVGDMIARVEPAAIFGSQMERHIGKRLDIPCGVISAPVHIQNFPLGYRPFLGYEGTNQIADLVYNSFTLGMEDHLLEIFGGHDTKEVITKSLSTDSDLTWDPESQAELSKIPGFVRGKIKRNTEKFARQNGMSKITVEIMYAAKEALNA
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PCXA_TRIEI
Sequence: MAISPWKQFKLSVLNANQWFRKTPERALNMAYDAANKIRSIEEEHFEGRKISNVSISYSNSTKSYFNSQLNRYLKIIQVRLAEFNTSISVVGTLDQNKVDKQKDKFDQNYQQEFPGRSSIILDKLEFIDQVSSRYYKSSNHEAQELNTDLEIPHSSSSIAIVSSNVNVNNYPNNVRAGSSQNQNNLAELKSNIPNTNFLPRSLLKTFKKIKQELDPEAETEVIRKFRKSQIKTLTSVRFILLVILVPLLIHQLSKITFVGYLVDNFMSLPHQQAELFLNSNMEEEALVKLHQYEEKLHFKMYLGQAPELFPELYESGKEITEIPKSEREELIEHKVEKKAQEIALEYKAKGNNGIKNIFCDFISLITFVIIISTRKRELEVLKSFMDDVVYGLSDSAKAFIIILLTDMFVGFHSPHGWEVILENITRHFGLPESRDFNFLFIATFPVILDAVFKYWIFRYLNRSSPSAVATYKNMNE
What is the function of this protein?
Involved in light-induced Na(+)-dependent proton extrusion.  Also seems to be involved in CO(2) transport.
What are the official names of this protein?
Proton extrusion protein PcxA.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISCS_AZOVI
Sequence: MKLPIYLDYSATTPVDPRVAQKMCECLTMEGNFGNPASRSHVFGWKAEEAVENARRQVAELVNADPREIVWTSGATESDNLAIKGVAHFNASKGKHIITSKIEHKAVLDTTRQLEREGFEVTYLEPGEDGLITPAMVAAALREDTILVSVMHVNNEIGTVNDIAAIGELTRSRGVLYHVDAAQSTGKVAIDLERMKVDLMSFSAHKTYGPKGIGALYVRRKPRVRLEAQMHGGGHERGMRSGTLATHQIVGMGEAFRIAREEMAAESRRIAGLSHRFHEQVSTLEEVYLNGSATARVPHNLNLSFNYVEGESLIMSLRDLAVSSGSACTSASLEPSYVLRALGRNDELAHSSIRFTFGRFTTEEEVDYAARKVCEAVGKLRELSPLWDMYKDGVDLSKIEWQAH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur from cysteine to produce alanine via an enzyme-bound persulfide intermediate.  Functions as a sulfur delivery protein for Fe-S cluster synthesis.  Cluster assembly on IscU homodimers proceeds sequentially from 1 2Fe-2S per dimer, to 2 2Fe-2S per dimer and finally 1 4Fe-4S per dimer.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRL33_ORYSJ
Sequence: MEEGEAKKTGLEGTGLSLPGSSHGNLRSAGSDQQLKQMLDSLKSSKSPAVINYGASWCRVCSQILPPFCRFSNEFKNLTFIYADIDECPETTQNIRYTPTFHFYRDGEKVDEMLGTGEERLHDRLWLHS
What is the function of this protein?
Probable thiol-disulfide oxidoreductase that may participate in various redox reactions.
What are the official names of this protein?
Thioredoxin-like 3-3, Thioredoxin-like 1.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: RLME_RICPR
Sequence: MTNNLSGYRNKIVRVKTSKKRPISSSNWLRRQLNDPYVAKARLEGFRSRAAYKLLEIHYKFRLFTPNMKIVDLGAAPGGWSQVASKLIKASDNNLNNKIISIDLLEIEPIVGVEFLQKDFFEKDTEELIIHNLEGKADIVMSDMASNTIGHKATDHMRTLLLCEQAFEFALKVLKPSCHFIAKIFRGGAETALLNKVKREFRTVKHFKPVSSRSESTEIYLVALNKK
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARP6_ARATH
Sequence: MSNIVVLDNGGGLIKAGQGGERDPTTVIPNCLYKPLSSKKFIHPSPLTTLSDEIDLTSAAVRRPIDRGYLINSDLQREIWSHLFTSLLHIAPSSSSLLLTEAPLSIPSVQRTTDELVFEDFGFSSLYIAHPQSLVHLYEASRQPDSILSKTQCSLVVDCGFSFTHAVPVLHNFTLNHAIKRIDLGGKAFTNYLKELVSYRSINVMDETFLVDDAKEKLCFVSLDLLRDLRLARNGNTLIKSTYVLPDGVTHTKGYVKDPQAAKRFLSLSEKESVVVMDKVGERKKADMNKNEIDLTNERFLVPETLFQPADLGMNQAGLAECIVRAINSCHSYLQPVLYQSIILTGGSTLFPQLKERLEGELRPLVPDHFDVKITTQEDPILGVWRGGSLLASSPDFESMCVTKAEYEELGSARCRRRFFH
What is the function of this protein?
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant H2A. F/Z leading to transcriptional regulation of selected genes (e. g.  FLC) by chromatin remodeling.  Binds to the promoter region of FLC chromatin.  Required for the activation of FLC and FLC/MAF genes expression to levels that inhibit flowering, through both histone H3 and H4 acetylation and methylation mechanisms.  Involved in several developmental processes including organization of plant organs, leaves formation, flowering time repression, and fertility.  Modulates photoperiod-dependent epidermal leaves cell development; promotes cell division in long days, and cell expansion/division in short days.  May be involved in the regulation of pathogenesis-related proteins (PRs).
What are the official names of this protein?
Actin-related protein 6, Protein EARLY IN SHORT DAYS 1, Protein SUPPRESSOR OF FRIGIDA 3.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP6 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localized in the nucleus during the interphase, but is released into the cytoplasm during the mitotic phase (PubMed:16141450). Associated to heterochromatin (PubMed:16141450). Localized at the nuclear periphery when interacting with SWC6 (PubMed:16155178, PubMed:17470967).
Protein: TRM1_SULIK
Sequence: MKLKEVTEGKVRIFVPDPKEYMIEGKFDPSWAPVFYNPKMTFNRDLSVIVVSLLKPKIILDALSATGIRGIRYYVESWKSEQLILNDKNSTAASLIQINVKNNGIENAKIYNKDANALLYEIKSEYIDIDPFGSPVPFILSSINATIRNGIVAFTATDLSPLEGSSRTSCRRKYDAINYKLSSSKELGLRILIGKIIREAATLEKTVHPLFSFYADYYYRLFVIVESGARKADENINKNLKYFGECPRCGFQTFVDENCKTKCPICGENFIIIGPLYIGPLHNMEFLKRMIDTYSDFNYLSSFNRIQKLLNVIEKEAKYKSVFYNISKLASKLKVSAIPPIDSILECLGDASKTHFAPTGIRTDKGYEEIIRCVKSLR
What is the function of this protein?
Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
What are the official names of this protein?
tRNA (guanine(26)-N(2))-dimethyltransferase, tRNA 2,2-dimethylguanosine-26 methyltransferase, tRNA(guanine-26,N(2)-N(2)) methyltransferase, tRNA(m(2,2)G26)dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
Protein: TRPA_RUEPO
Sequence: MTRIDAKFAELKAQGKKAFVSYVMAGDPDFDTSLELVKGLPGAGVDIIELGLPFTDPMADGPTIQLAGQRALDGGMTLQRTLDLATEFRKTDNTTPIVMMGYYNPIYSRGVDRFLADAKAAGIDGLIVVDLPPEEDSELCLPAQAAGLNFIRLATPTTDDKRLPRVLQNTSGFVYYVSITGITGSAEAEATDVGPEVARIKAATDLPVIVGFGINTPEKSRAIASVADGAVVGSAIVGQIGAGKPVAEVLAFVKTLSDGAHSA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: UGPA_MUSAC
Sequence: MADAKIAKLQSAVAELNQISENEKSGFISLVSRYLSGEAEQIEWSKIQTPTDEVVVPYDTLSPPPEDLEATKKLLDKLAVLKLNGGLGTTMGCTGPKSVIEVRNGFTFLDLIVIQIESLNKKYGCNVPLLLMNSFNTHDDTQKIVEKYANSNIEIHTFNQSQYPRLVMEDFQPLPSKGHAGKDGWYPPGHGDVFPSLMNSGKLDALLSQGKEYVFIANSDNLGAIVDIKILNHLINNQNEYCMEVTPKTLADVKGGTLISYEGRVQLLEIAQVPDAHVNEFKSIEKFKIFNTNNLWVNLKAIKRLVEADALKMEIIPNPKEVDGVKVLQLETAAGAAIRFFDHAIGINVPRSRFLPVKATSDLLLVQSDLYMLVDGFVIRNKARTNPSNPSIELGPEFKKVANFLSRFKSIPSIVELDSLKVSGDVWFGEGVVLKGNVSIAAKSGVKLEISDGAVLENKVINGPEDI
What is the function of this protein?
Plays a central role as a glucosyl donor in cellular metabolic pathways.
What are the official names of this protein?
UTP--glucose-1-phosphate uridylyltransferase, UDP-glucose pyrophosphorylase, UDPGP, UGPase.
What is the protein family that this protein belongs to?
Belongs to the UDPGP type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAA_MYCTA
Sequence: MSRLSEPSPYVEFDRRQWRALRMSTPLALTEEELVGLRGLGEQIDLLEVEEVYLPLARLIHLQVAARQRLFAATAEFLGEPQQNPDRPVPFIIGVAGSVAVGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELQRRNLMHRKGFPESYNRRALMRFVTSVKSGSDYACAPVYSHLHYDIIPGAEQVVRHPDILILEGLNVLQTGPTLMVSDLFDFSLYVDARIEDIEQWYVSRFLAMRTTAFADPESHFHHYAAFSDSQAVVAAREIWRTINRPNLVENILPTRPRATLVLRKDADHSINRLRLRKL
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PMK1_MAGO7
Sequence: MSRANPPSNSSGSRKISFNVSEQYDIQDVVGEGAYGVVCSAIHKPSGQKVAIKKITPFDHSMFCLRTLREMKLLRYFNHENIISILDIQKPRSYETFNEVYLIQELMETDMHRVIRTQDLSDDHCQYFIYQTLRALKAMHSANVLHRDLKPSNLLLNANCDLKVCDFGLARSAASQEDNSGFMTEYVATRWYRAPEIMLTFKEYTKAIDVWSVGCILAEMLSGKPLFPGKDYHHQLTLILDVLGTPTMEDYYGIKSRRAREYIRSLPFKKKVPFRTLFPKTSDLALDLLEKLLAFNPVKRITVEEALKHPYLEPYHDPDDEPTAPPIPEEFFDFDKHKDNLSKEQLKQFIYQEIMR
What is the function of this protein?
Mitogen-activated protein kinase; part of the MST11-MST7-PMK1 MAP kinase (MAPK) cascade that is essential for appressorium formation, penetration and invasive growth (PubMed:8946911, PubMed:11952120, PubMed:15749760, PubMed:21283781, PubMed:23085322, PubMed:23454094, PubMed:27059015).  Central regulator of appressorium development that acts downstream of the cAMP signal (PubMed:8946911, PubMed:23591122).  The MST11-MST7-PMK1 MAP kinase cascade transduces signals from the cell surface sensors MDB2 and SHO1 that recognize various surface signals such as surface hydrophobicity, cutin monomers, and rice leaf waxes (PubMed:21283781).  Regulates expression of secreted fungal effector proteins implicated of host immune defenses, preventing reactive oxygen species generation and excessive callose deposition at plasmodesmata (PubMed:29567712).  Furthermore, controls the hyphal constriction required for fungal growth from one rice cell to the neighboring cell, enabling host tissue colonization and blast disease (PubMed:29567712).  Targets downstream of the PMK1-MAPK pathway include transcription factor MST12 and pathogenicity-related genes GAS1 and GAS2, both of which are expressed during appressorium formation, even if regulation of MST12 is not associated with expression of GAS1 or GAS2 (PubMed:12215509, PubMed:11952120, PubMed:23454094).
What are the official names of this protein?
Mitogen-activated protein kinase PMK11, MAPK PMK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Protein: Y2450_BACVZ
Sequence: MSSFDKTMKFNFSDDSAETNVEEVLNTVYDALQEKGYNPINQIVGYLLSGDPAYIPRHRDARNLIRKLERDELIEELVKSYLEQHKEA
What are the official names of this protein?
UPF0297 protein RBAM_024500.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: PUR9_NITOC
Sequence: MKPIARALISVSDKTGIVPFAHRLQARGVKILSTGGSAQLLQKNNIGATEISTYTGFPEMMGGRIKTLHPKIHGGILGRRETDATTMAEYNIAPIDLVAVNLYPFEQTVAKPDCDLATAIENIDIGGPTLLRAAAKNHAAVTVIVDPDDYERVLREMEANGGALSSSTRFELAVKSFEHTARYDATIANYLGALTPNGEKSAFPRSYNIQFAKKQEMRYGENPHQRAAFYVEQPPPAGTIATAQQLQGKTLSFNNIADTDAALACVKAFREAPTCVIVKHANPCGVATGINLQEAYERAYAADPVSAFGGIIAFNEPLDPTTAKTIIKRQFAEVIIAPAVTTTAQEILTSKPNIRVLACGEWSSQTAAGWDYKRIVGGLLLQDQDTDTVPLEALQTVTERSPTPQELKDLLFAWQVVKFVKSNAIVYAKNGRTIGVGAGQTSRVMSSQIAELKAKEAGFSTQNAVLASDAFFPFRDGLEAAAKAGICAVIQPGGSRRDKEVIAAANEWDMAMLFTGMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: TFE3_BOVIN
Sequence: MSHAAEPAQDGVEASAEGPRAVFLLLEDRRPADSAQLLSLNSLLPESGIVADIELENVLDPDSFYELKSPPLSLRSSLPISLQATPATPATLSASSSAEGSRTPAMSSSSSSRVLLRQQLMRAQAQEQERRERREQASSFPSPAPASPAISVVGVSAGGHTLGRPPPAQVPREVLKVQTHLENPTRYHLQQARRQQVKQYLSTTLGPKLASQALTPPPGGASVQPLPTPEAAHAPGPTSSAPNSPMALLTIGSSSEKEIDDVIDEIISLESSYNDEMLSYLPGGNTGLQLPSTLPVSGNLLDVYNNQGVATPAITVSNSCPAELPNIKREISETEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSSDPEMRWNKGTILKASVDYIRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQELELQAQIHGLPVPPTPGLLSLAATSASDSLKPEQLDVEEEGRPGTAIFHATGGLAQSAPHQQPPPPPSDALLDLHFPSDHLGDLGDPFHLGLEDILMEEEEGVVGGLSGGTLSPLRAASDPLLSSVSPAVSKASSRRSSFSMEEES
What is the function of this protein?
Transcription factor that acts as a master regulator of lysosomal biogenesis and immune response (By similarity).  Specifically recognizes and binds E-box sequences (5'-CANNTG-3'); efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF (By similarity).  Involved in the cellular response to amino acid availability by acting downstream of MTOR: in the presence of nutrients, TFE3 phosphorylation by MTOR promotes its cytosolic retention and subsequent inactivation.  Upon starvation or lysosomal stress, inhibition of MTOR induces TFE3 dephosphorylation, resulting in nuclear localization and transcription factor activity (By similarity).  In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity (By similarity).  Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer.  It also binds very well to a USF/MLTF site.  May regulate lysosomal positioning in response to nutrient deprivation by promoting the expression of PIP4P1 (By similarity).  Acts as a positive regulator of browning of adipose tissue by promoting expression of target genes; mTOR-dependent phosphorylation promotes cytoplasmic retention of TFE3 and inhibits browning of adipose tissue.  Maintains the pluripotent state of embryonic stem cells by promoting the expression of genes such as ESRRB; mTOR-dependent nuclear exclusion promotes exit from pluripotency (By similarity).  Required to maintain the naive pluripotent state of hematopoietic stem cell; mTOR-dependent cytoplasmic retention of TFE3 promotes the exit of hematopoietic stem cell from pluripotency (By similarity).
What are the official names of this protein?
Transcription factor E3.
What is the protein family that this protein belongs to?
Belongs to the MiT/TFE family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=When nutrients are present, phosphorylation by MTOR prevents nuclear translocation and activity. Conversely, inhibition of mTORC1, starvation and lysosomal disruption, promotes dephosphorylation and translocation to the nucleus.
Protein: SYP_HAMD5
Sequence: MRTTQYLLSTLKELPADAEIISHQLMLRAGMIRKLASGLYTWLPTGTRVLKKIENIVREEMNKAGAIEVVMPIVQPADLWQESERWEHYGPELLRFADRSERPFVLGPTHEEVITDLVRNEISSYKQLPLNFFQIQTKFRDEIRPRFGIMRAREFLMKDAYSFHNTLESLQETYQTMYQAYTKIFERMQLNFRAVQADTGSIGGSRSHEFQVLADSGEDEIVFSTVSDFAANIELAEALVPHEKRASPCETLRIIDTPNAKTIDQLVEQFSIPIEKTLKTLIVYAHKDSGHKLLALLVRGDHLINKVKAEKSPQVAKPLTFASEEDIRAHIGAGPGSLGPLHLKMPIIADRAVAVMSDFSAGSNKEDQHYFGINWERDLPLPIIEDLRNVVEGDPSPDGKGTLLIKRGIEVGHIFQLGTKYSQAMGAKVQGENGRQQMMIMGCYGIGVSRLVAAAIEQHHDQHGILWPEAIAPFQVAILPIHLKKSDAVRQEAERLYAELSSLGMDVIFDDRQERPGVMFADMELIGIPHTLIIGDRDLENNELEYRYRGIDDHKKQQLKISDVVSFLLEKINSHFNPK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_ACIBT
Sequence: MAIGLVGRKCGMTRIFTDAGVSVPVTVIEVDPNRITQIKTLETDGYQAVQVTTGERRESRVTNAQKGHFAKAGVAAGRLVKEFRVTEAELEGREVGGTIGVDLFTVGQIVDVTGQSKGKGFQGGVKRWNFRTQDATHGNSVSHRVLGSTGQNQTPGRVFKGKKMAGHLGDERVTVQGLEIVSVDTERSVLVVKGAIPGATGGDVIVRPTIKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: ODFP2_MESAU
Sequence: RTLRDLLREQHSKEDSERLMEQQGALLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRCKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKEL
What is the function of this protein?
Seems to be a major component of sperm tail outer dense fibers (ODF).  ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail.  May have a modulating influence on sperm motility.  Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles.  Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes.  Required for the formation and/or maintenance of normal CETN1 assembly (By similarity).
What are the official names of this protein?
Outer dense fiber protein 2, 84 kDa outer dense fiber protein, Cenexin, Outer dense fiber of sperm tails protein 2.
What is the protein family that this protein belongs to?
Belongs to the ODF2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Cell projection, cilium, flagellum. Note=Localized at the microtubule organizing centers in interphase and spindle poles in mitosis. Localized at the distal/subdistal appendages of mother centrioles.
Protein: UREA_CRYNJ
Sequence: MHLLPRETDKLIVTTLGTLAQRRLARGLILNRAETIALISSQLQEFIRDGRHSVAELMDLGKKMLGRRHVRKGVPESIHTIQVEGTFPDGVFLVTVDDPISSDDGDLNNAFYGSFLPIPSADVFPAAPEPADTLLGALICRKEPIKINASRRRFKLEVKNAGDRPIQVGSHYHFLETNPALIFDRLLSYGYHLDIPAGTAVRFEPGEKKTVTMVEFGGKKIFHGGSGLASGSFDENLRETKVKEMVEKGGFGHKDQEKVEEGPTTEMNREVYASMFGPTTGDKIKLADMDLWIEVEKDYTVYGEECKFGGGKVLRDGGGQASGRHEHEVLDLVITNALIVDWNGIYKADIGVKNGIIVGIGKAGNPDMMDGVTDGMIVGSSTEVIAGEKLIITAGALDVHVHYICPQLMTEALASGITTVVGGGTGPADGSNATTCTSSSFYMQNMIKATDTVPLNFGFTGKGNDSGTNALRDVIEAGACGLKVHEDWGATPEVIDRALSIADEYDVQVNLHSDTLNESGYVESTLAAIKGRTIHSYHTEGAGGGHAPDIIVVCEYENVLPSSTNPTRPYAVNTLDEHLDMLMVCHHLDKSIPEDIAFADSRIRSETVAAEDVLQDTGAISMISSDCQAMGRIGEVITRTWRTAAKMKQFRGPLEGDEPTRDNNRVKRYVAKYTINPAITHGMSHLIGQVAVGCLADLVFWTAESFGARPEMILKGGVIAWAAMGDANASIPTVQPVIGRPMWGSQPEAAALNSIVWVSQASLDKDLVKRFNIKKRAEAVKNCRAIGKKDMKWNDSMPKMTVDPETYDVHADGVLCDVPPADKLPLTKRYFVY
What are the official names of this protein?
Urease, Urea amidohydrolase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
Protein: Y706_MYCUA
Sequence: MARTEDDSWEITESVGATALGVASARAAETRSQHPLISDPFAQVFLDAVGDGVWNWHSAPQLPAELLEIEPDLPLQMEAMVSYMASRTAFFDEFFLDATRAGIGQAVILAAGLDSRAWRLPWPAGTTVFELDQPRVLEFKAATLAEHGAEPACGRVAVAVDLRQDWPTALRQAGFDPSVSSVWSAEGLMPYLPAVAQDLLFERVQGLTVRASRIAVEALGPKFLDPQVRANRSARIERIRAVMAHVEPQREIPRTDELWYFEEREDVGDWFRRHDWDVTVTPSGELMAGYGRAAAAQVEDRVPTNLFVAAQRN
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MUL_0706.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: PNP_BARBK
Sequence: MFKTHKVEIEWAGRPLTIETGRVARQADGAVVATYGETVVLATVVSAKAPKPDQDFFPLTVNYQEKTYAVGKIPGGYFKRESRPSENETLISRLIDRPIRPLFVDDYKNDTQVIVSVIQHDLENNPDILSMIAASAALTLSGIPFMGPIAGARVGYCNGHYVLNPTLDEMPESKLDLVVAGTENAVLMVESEAHELSEEVMLGAITFGQKGFQPVIDAIIQLAEVAAKEPREFIPEDFSDLEKTMLKMIEKDLRKAYTITDKQQRYDAIDAIKTEILSKFAPEMEVNCELTADKIATVFKRLQAKIVRWNILDTGKRIDGRDLSTVRPIQSEVGILPRTHGSALFTRGETQALVVATLGTSEDEQYVDLLTGVCKETFLLHYNFPPFSVGETGRLSSPGRREIGHGKLAWRAIHPMLPTKEAFPYTIRVVSEITESNGSSSMATVCGTSLALMDAGVPLARPVAGIAMGLIKEGERFVILSDILGDEDHLGDMDFKVAGTKNGITSLQMDIKIDGITEDIMKIALEQAKDGRNHILNEMAKALTDARTELSEFSPRIEMMTIPVEKIREVIGSGGKVIREIVEQTGAKINIEDDGTIKIASPDTKSIETAKSWIHSIVDEPEVGTIYQGTVVKTTEFGAFINFFGSHDGLVHISQLASKRVAKTTDVVKEGDKVWVQLMGFDERGKIRLSMKVVDQQTGKEIPQDDLIKTEKEQNPDEKNKSEKKRHNRKKED
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPS2_SCHPO
Sequence: MPSGAQGNTQSAAYKRIVNVSRNFQFKAALNKDTREWTFQHRSSGTALYSAIASLGDPSSPWDAVYVASPGPVQISEGNDHTVETKIDEAAVVHRSSSIVISPEDQEIFLKKATEYYRKKNIEADIVPVWGKVQRVPQAKSSSATITPSVSNKLSTAYQSIKSEALKDGPMYADSVLWDVLHYRIPTLDGYQQHNLWKNFTRWSQYFADNIVSNYRPGDLILIHDYSLFLLPRLIRKQLSDAPIVFFLHAPFCTSEVFRCLSKRAEILKGVLASNVIAMQTDSYTRHFLSTCSNVLGLETTSTHIDTSDGFRVVVFSSHVSIDVPRVYSRCNSKPVSLKIQQLKSLYPSDKKLIVGRDQLTKACGVTHKLRAFRELLIHFPKWRGHVVLIQITSLPVGNNYSNEELKKTENLVAQINSEFGSLDYTPVIHFHQLLDPDEYYALLSVANIACVSSVRDSMNTMALEYVACQQKNKGSLILSEFSGTAELLLSAYLVNPYDYSRFAETINYCLNMTEKERERRFSSLWKQATSQSSQQWIYKLINRAAYEVKALESHMTTPLLTYNILIKPYRNAKRRLFLLDYDGTLIESARNSIDAVPTDRLLRTLKRLASDSRNIVWILSGRSQKFMEEWMGDISELGLSSEHGSAIRPPLAGSWSSCAENLDLSWKDTVRDFFQYYVERTPGSYIEEKKHSISWCYQNANTTYSKFQSLECQTNLEDMLKHYDVEISPAKSFLEVHPNYLNKGSIVRRILKRSGSVDFVFCAGDDKTDENMFEVFLPTAFSNSHLIDEIDSTEYSGSHHTDDNSDANKVENVKVATFRVHIGLTDKPTLSDYHLPAPRDLGELLHNL
What is the function of this protein?
Phosphatase catalytic subunit of the trehalose synthase complex that catalyzes the production of trehalose from glucose-6-phosphate and UDP-glucose in a two step process.
What are the official names of this protein?
Trehalose-phosphatase, Trehalose synthase complex catalytic subunit tps2, Trehalose-6-phosphate phosphatase, TPP.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the trehalose phosphatase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.