PharMolix/UniProtQA huggingface dataset:
Protein: EFTU2_ECOLI
Sequence: MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLS
What is the function of this protein?
(Microbial infection) Upon infection by bacteriophage Qbeta, part of the viral RNA-dependent RNA polymerase complex.  With EF-Ts may provide a stabilizing scaffold for the beta (catalytic) subunit.  Helps separate the double-stranded RNA of the template and growing RNA during elongation (PubMed:22245970).  With the beta subunit helps form the exit tunnel for template RNA.  The GTPase activity of this subunit is not required for viral RNA replication (PubMed:20798060).
What are the official names of this protein?
Elongation factor Tu 2, EF-Tu 2, Bacteriophage Q beta RNA-directed RNA polymerase subunit III, P-43.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein. Note=Between 50-80% of the protein is associated with the cell inner membrane. Localization to the membrane has been suggested to follow nutrient stress.
Protein: M050_ARATH
Sequence: MSGVYLTVPQAPELINERIPSFTASCSEVAPEHSEMPLTVIYIVLPVVMESQLESTLDILWIPESYSTLMQENMGFPYHGRLQILAGARDSLYLGRDAVVLLCPSLPFPTFTKWLIQVILLLSYWGSGGFG
What are the official names of this protein?
Uncharacterized mitochondrial protein AtMg00050, ORF131.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GALT_LACPL
Sequence: MTSLDQFVTAVIASPSQYTELDRIYVHNRVLGLVGEGDPIAASDDQLTSLTDALVKTAIQNGKIEATQSDEDILADQLMDLVTPLPSVLNQRFWDKYQVSPQTATDYFFNLSKANDYIKTRAIAKNVVFPAKTPFGDLEITINLSKPEKDPKAIAAARNQPQDGYPLCQLCMQNEGYLGRLGYPARSNHRIIRLTLGGNTWGFQYSPYAYFNEHSIFLDQEHRPMVINRQTFTNLLEIVQQFPHYFVGSNADLPIVGGSMLSHEHYQGGRHEFPMMKAPIARTIDLGIAGVKAGIVKWPMSTIRLTSQDLVALTDAAVKIHETWKNYSDESVDVRAYTDGTRHHTTTPIARKVGDDYVLDIVLRDNQTSAEFPDGIFHPHQDVQHIKKENIGLIEVMGRAILPARLKTELAEVGKYLLDQPNQMVAMHQAWAAQLKATNTITADNVTTVIDTAVGNVFARVLADAGVFKWDDAGEAAFDRFVAAMHD
What are the official names of this protein?
Galactose-1-phosphate uridylyltransferase, Gal-1-P uridylyltransferase, UDP-glucose--hexose-1-phosphate uridylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISX_GLOVI
Sequence: MLRLITQLSEAQTEIKRIAARTHSEQVQHQEATVREILQNVRRQGDEALLRYTLEFDQVRLAPGDLVVGAAELDAAYQRVSTSLLKAIRLAKQRIEQFHRERICKSWVQFQDRGIVLGRRYTPVDAAGLYIPGGRASYPSSVLMSAIPAVVAGVPRIVLVTPPNPEGKINPAVLVAAQESGVHEIYRIGGAQAIGALTYGTRTIAPVSVIAGPGNIYVTLAKKLVYGEVGIDSLAGPSEVLIIADSTANPVFLAADMLAQAEHDSLASAILITPDGRLAERTIEAVDRQLENHPRRTLTEKSLANYGLVIVTADLAEAAALSNLFAPEHLELEVEDPWELLEKVRHAGAIFLGHATPEAVGDYLAGPSHILPTSGTARYASGVGVETFQKCSSLVQYTPQALAEVGEAIDALTAAEGLPSHGDSVRLRLQQYENPHSPTQQQQEE
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: PSAJ_GLOC7
Sequence: MKGLPKFLSLGPVLLVLWLSVQATLLIVINIIYPDLLFYPLS
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: SIX3H_LEIHE
Sequence: MKLLLLLTISASMLIEGLVNADGYIRGGDGCKVSCVINHVFCDNECKAAGGSYGYCWAWGLACWCEGLPAEREWDYETDTCGGKK
What is the function of this protein?
Depressant insect beta-toxins cause a transient contraction paralysis followed by a slow flaccid paralysis.  They bind voltage-independently at site-4 of sodium channels (Nav) and block action potentials, primarily by depolarizing the axonal membrane and suppressing the sodium current.  This depressant toxin is active only on insects.  It is found in a relatively small amount in the venom.
What are the official names of this protein?
Beta-insect depressant toxin Lqh-dprIT3h.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TRUA_LACPL
Sequence: MTTRYKVVLAYDGTNFAGFQRQPHQRTVEQVVTKAVNKMAKDPVEPIVIYGAGRTDAGVHAFGQTLHFDLPYEINPEGVRRGLNSMLPMDTIVKAVSIVPNDFHARYDTVGKRYWYRAYQNEFVDPFKRHYTGHFKFAADIDRIQQAIGDLEGRHDFSTFVASGSQAHDHVREIYSAKAWALPDEREIQFEFCGSGFLYNQVRIMVAVLMEIGQGRRAVDCIPALLAAKDREQARGTAPAAGLYMKKVYYEQNELQADLIKY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RL13_CLOK5
Sequence: MKSYIAKAEQIERKWYVVDAAGKPLGRVASQVASVLRGKHKPIFTPHVDTGDFVIVINSEKVLLTGKKLDQKMLRHHSLYPGGLKETPYREALNKKPEFVFQEAVRRMLPKGVLGRKMLKKLKVYRGTEHNNEAQKPEVLELKY
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: ANKH_XENLA
Sequence: MVKLPSLTPYWPLIRFLVPLGITNIAIDFGEQALNRGIAAVKEDAIEMLASYGLAYSLMKFFTGPMSDFKNVGLVFVNSKRDRMKAVLCMVVAGIIAAVFHTLIAYSDLGYYIINKLHHVDESVGGKTRKAFLYLAAVPFMDAMAWTHAGILLKHKYSFLVGCASISDVIAQVVFVAILLHSHLECREPLLIPILSLYIGALVRCTTLCLGYYKNIHDKIPESSGPEIGGDATIKKMLSFWWPLALILATQRISRPIVNLFVSRDLGGSTAATEAVAILTATYPVGHMPYGWLTEIRAVYPAFDKSNPGSKLANSSNPVSKTHIKNXTFACMALSLTLCFVMFWTPNVSEKILVDIIGVDFAFAELCVIPLRIFSFFPVPVTVRAHLTGWLMTLKKTFVLAPSSILRIIVLISSLIVLPYLGVHGATLGVGSLLAGFVGESTMVAIASLYVYRKQKKKSETENAVEGEDSAMTDLPHNEELTDIVEIKEDGE
What is the function of this protein?
Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.
What are the official names of this protein?
Progressive ankylosis protein homolog, ANK.
What is the protein family that this protein belongs to?
Belongs to the ANKH family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: H2A1_XENLA
Sequence: MSGRGKQGGKTRAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQSVLLPKKTESAKSAKSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A type 1.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: JZ12A_CHIGU
Sequence: MKMSALFVIFGLALLFCNSFAAELKATGRGCGGLMDGCDGKSTFCCSGFNCSPTWKWCVYARPGRR
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U1-theraphotoxin-Cg1d 1, U1-TRTX-Cg1d, Jingzhaotoxin-12.1, JZTX-12.1, Peptide F4-15.91.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 46 (Jztx-7/10/12) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CDVC_SULAC
Sequence: MSAQVMLEEMARKYAINAVKADKEGNAEEAITNYKKAIEVLAQLVSLYRDGSTAAIYEQMINEYKRRIEVLKELIPADGAGNGNGKHSQVSVDDLVMKEKPKVNFNDIVGLEDVKEALKEAIVYPTRRPDLFPLGWPRGILVYGPPGCGKTMIAAAVANEIDSYFIQVDAASVMSKWLGEAEKNVAKIFNSARELSKKDGKPVIIFIDEIDALLGTYNSENGGEVRVRNQFLKEMDGLQDKSENFKVYVIGATNKPWRLDEPFLRRFQKRIYIRLPDIEQRKSLLLHYTSKIKMDNVNIDELAKMTEGYTASDIKDIVQAAHIRVVKEMFDKKLEQPRAVNMEDFKEILKIRKPSVNSEVIKVYEAWHEKYKAL
What is the function of this protein?
Part of a cell division machinery (PubMed:18987308, PubMed:19008417).  The CdvA, CdvB and CdvC proteins polymerize between segregating nucleoids and persist throughout cell division, forming a successively smaller structure during constriction (PubMed:18987308).
What are the official names of this protein?
Cell division protein C.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Forms band-like structures between segregating nucleoids (PubMed:18987308). Localizes to the mid-cell in dividing cells (PubMed:19008417).
Protein: RS7_MYCTA
Sequence: MPRKGPAPKRPLVNDPVYGSQLVTQLVNKVLLKGKKSLAERIVYGALEQARDKTGTDPVITLKRALDNVKPALEVRSRRVGGATYQVPVEVRPDRSTTLALRWLVGYSRQRREKTMIERLANEILDASNGLGASVKRREDTHKMAEANRAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: KIF5_DICDI
Sequence: MATSCNIRVMCRFRPLNEREKALKENQTCVTFPDETQVIVSGQPFTFDRVFTPESTQKEVFESVKDTIHDVLLGYNGTLLAYGQTGSGKTFTMGSAAAESDFENVEQLGIIPRGNHLIFNTIAEESDGNAEFTIKCSYLEIYMENIQDLLNPKNNKQLKIRESKSQGIYVEGLTEEYVASEEDIMELIQVGESSRSVAKTNMNQRSSRSHSILIIAIEQKSSDGSKKRGKLNLVDLAGSEKVSKTGAEGIVLEQAKKINQSLSLLGNCIHALTDSKREHIPFRDSKLTRLLQDSLGGNTKTTLLVTASPHFNNVDETISTLKFGARAKSIKNNVKVNQEKSAAELQIIVNALTKELSILKVYSISLENLVNYFKSSSYQPGNPIPKELEPNKQNLLLLQQQSNSSSGGGGSGSSGGSSNGSLMMKPRSTTPTPPSINRPHSSASTHRHSIAITGTHSKEGSGGGLTSSISSSSISSMSSLSSSIDNDYNGSSLDDSNGSNGLFNPLAIVEMSIEMEKMKEDTQLLIEKFKDEISEITIQYQSTQEELNQCRQQLDQIKEQLEQQRSQFIKEQSLLKESERNATLDSTSKDLKIQSLISKIEDLRLLASQVIQYLERKRLSDDFDIGIFMGSQDGANGDSANMFSLISNSIDQGTYEDDVNIEDIIRYLSEEEVLTMQVKLQLQNKVHQLEQKIQQLVSDLNTTEINYNQSILQCQKFESENSLIKRKFKSMFSSSNNNNNNNNSPPSSPSSKLLIQSSNNNNNFDSNLNSSSLSSSLPSSNGIEQDQQVDHQVDHQVENDHLVNDEDNKLLDENSKLKENELKLLLEIKNLKLQSEKSNDETLKWKDELSIKSALYQNQILNLQNENQSLSNKLNVEKQQKQSSQSQQIEFATKLNDLIKSSEDDKELYRNEKNQMELEIASLKASLDEMDLKNKELQDQLISTQRLIGARRVVKIVRGGADSMKTALATKEVFGQFTLRKTENSKTLFQ
What is the function of this protein?
Microtubule-associated force-producing protein that plays a role in organelle transport.  Its motor activity is directed toward the microtubule's plus end (By similarity).  May connect microtubules to actin filaments.  Associates with actin-based structures in cells and is likely involved in the organization of actin cytoskeletons in such structures.
What are the official names of this protein?
Kinesin-related protein 5, Kinesin family member 5, Kinesin-1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: LUCI_PHOPY
Sequence: MEDAKNIKKGPAPFYPLEDGTAGEQLHKAMKRYALVPGTIAFTDAHIEVNITYAEYFEMSVRLAEAMKRYGLNTNHRIVVCSENSLQFFMPVLGALFIGVAVAPANDIYNERELLNSMNISQPTVVFVSKKGLQKILNVQKKLPIIQKIIIMDSKTDYQGFQSMYTFVTSHLPPGFNEYDFVPESFDRDKTIALIMNSSGSTGLPKGVALPHRTACVRFSHARDPIFGNQIIPDTAILSVVPFHHGFGMFTTLGYLICGFRVVLMYRFEEELFLRSLQDYKIQSALLVPTLFSFFAKSTLIDKYDLSNLHEIASGGAPLSKEVGEAVAKRFHLPGIRQGYGLTETTSAILITPEGDDKPGAVGKVVPFFEAKVVDLDTGKTLGVNQRGELCVRGPMIMSGYVNNPEATNALIDKDGWLHSGDIAYWDEDEHFFIVDRLKSLIKYKGYQVAPAELESILLQHPNIFDAGVAGLPDDDAGELPAAVVVLEHGKTMTEKEIVDYVASQVTTAKKLRGGVVFVDEVPKGLTGKLDARKIREILIKAKKGGKSKL
What is the function of this protein?
Produces green light with a wavelength of 562 nm.
What are the official names of this protein?
Luciferin 4-monooxygenase, Luciferase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: MRAY_ERWT9
Sequence: MLVWLAEHLVTFYSGFNVFSYLTFRAIVSLLTALFISLWMGPRMIARLQEMSFGQVVRNDGPESHFSKRGTPTMGGIMILTSITVSVLLWAYPSNPYVWCVLFVLVGYGIVGFVDDYRKVVRKDTKGLIARWKYFWQSAIALVVAFVMYMIGKDTPATELVVPFFKDVMPQLGLLYLLLAYFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFALVAWATGNVKFAEYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CRTC2_MOUSE
Sequence: MATSGANGPGSATASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTRLQAQKLRLAYTRSSHYGGSLPNVNQIGCGLAEFQSPLHSPLDSSRSTRHHGLVERVQRDARRMVSPLRRYPRHIDSSPYSPAYLSPPPESGWRRMMPWGNLPAEKGQLFRLPSALNRTSSDSALHTSVMNPNPQDTYPGPTPPSVLPSRRGGGFLDGEMDAKVPAIEENVVDDKHLLKPWDAKKLSSSSSRPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTPLDPEETVYPSLSGGNSTTNLTHTMTHLGISGGLGLGPSYDVPGLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLAHHALPTTSLGHPSLSAPALSSSSSSSSTSSPVLSAPPYPASTPGASPRHRRVPLSPLSLPAGPADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLPTDQRLPPYPYSPPSLVIPTHPPTPKSLQQLPSQACLVQPSGGQPPGRQPHYGALYPPGSSGHGQQPYHRPINDFSLGNLEQFNMESPSTSLVLDPPAFSEGPGFLGSEGSMSGPQDPHVLNHQNLTHCSRHGSGPNIILTGDSSPGFSKEIAAALAGVPGFEVSASGLELGLGLEDELRMEPLGLEGLTMLSDPCALLPDPAVEDSFRSDRLQ
What is the function of this protein?
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites (PubMed:29211348).  Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated (PubMed:29211348).  Acts independently of CREB1 'Ser-133' phosphorylation.  Enhances the interaction of CREB1 with TAF4.  Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway.  Regulates the expression of specific genes such as the steroidogenic gene, StAR.  Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells (By similarity).
What are the official names of this protein?
CREB-regulated transcription coactivator 2, Transducer of regulated cAMP response element-binding protein 2, TORC-2, Transducer of CREB protein 2.
What is the protein family that this protein belongs to?
Belongs to the TORC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocated from the nucleus to the cytoplasm on interaction of the phosphorylated form with 14-3-3 protein (By similarity). In response to cAMP levels and glucagon, relocated to the nucleus (PubMed:16148943).
Protein: SYH_RHOPT
Sequence: MAEKPKKPQKLRARLPRGLADRGPAEIAATRAMVEKIREVYERYGFEPVETPAFEYTDALGKFLPDQDRPNEGVFSLQDDDEQWISLRYDLTAPLARYVAENFDQLPKPYRSYRFGWVFRNEKPGPGRFRQFMQFDADTVGSGSPAADAEMCMMAADTMEALGIPRGSYLVKLNNRKILDGVLEAIGIGGDEHIKQRLVVLRAIDKLDRLGLQGVEQLLGEGRKDESGDFTRGASLNAGQIRDVITLLNFAGWGDIVDGSNTHTLDEWEGLRFSVNSTFSAGIQDLRQITKITEASGYDTGRIRVDNTVVRGLEYYTGPVFEVELLLDTKDEKGRPVRFGSVGGGGRYDGLVSRFRGEPVPATGFSIGVSRLQAALTLIGQLGNKPQAGPVVVTVFGGEIAGYQKMVATLRKAGIRAELYLGNPKHSLGQQMKYADKRNSPCAIIQGSDEKQQGIVQIKDLILGAELASLEKDRDEYLKKQAEAQFSCKEDEMVAKVQELLQRRGVAWG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX41_THUOB
Sequence: MLATGALSLVGKRAISTSVCLRGGHGVAKVEEYTLPAYFDRRENPLPDICYVQALSPEQQSLKEKEKGSWAALSNEEKIALYRISFKQSFAEMNKGSSEWKSVVGGMLFFIGFTGLVVLWQRKYVYGAVPHTFDPEYKAKELQRMLDMRINPVEGFSAHWDYENKQWKK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial, Cytochrome c oxidase subunit IV isoform 1, COX IV-1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase IV family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: NNRE_DROER
Sequence: MDLKYLNQKEAIDVDQELFTEYKFSVDQLMELAGLSCAHAVAKCFPAEKHPRILVCCGPGNNGGDGLVAARHLSLMGYTPTIYYPKPTAKPLFENLSHQCQMMGICGVKECPSVESAAANYDLILDALFGFSFKPPVRADFVAVVELMQQTKLPIASVDIPSGWDVEKGKLTECDVEPALLISLTAPKLCARQFRGEHHYLGGRFVPPALQRKYELNLPVYPGNELCVKL
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
Protein: ATPD_BACP3
Sequence: MNQEVIAKRYASALFQIALEQGQLDRIEEDVRAVRQALAENGEFLSLLSYPKLSLDQKKALIREAFAGVSTPVQNTLLLLLERHRFGLVPELAGTVSRPRSTTARGIAKAVAYSGAASTDEELRALSDVFAQKVGKQTLEIENIIDPELIGGVNVRIGNRIYDGSVSGQLERIRRQLIG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS2_FRATW
Sequence: MSLMKEMLSAGVHFGHKKAFWNPQMKEYIFGINHGVHIINLEKTVPLFQDAVNFVGKTVANGGKILFVGTKRQAQDIVEAEAKRCGMPFVSHRWLGGMLTNYKTVRQSIKRLAQLEKMREDGTLESLTKKEMLQNIRTIEKLEKVLGGIKEMGGLPDAIVVIDSNKEHIAIQEAQKLGIKVVAIVDTNSNPEGIDYIIPGNDDAVKSISFYMKKFADAVIDAQGLDRAVEAKADEAAQA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: FUB1_YEAST
Sequence: MIENKVELVAELVLESIGKTEVVSRHTEGTKSCQVSFRIKDSPSEKGSTSFLSELVVIQTLDDNDKYTVVIRHGTSITMACVVGYSDFKLPTELKWPLERESLPVEPDLKPIMTQLKRQTAGSADMPKFDDEYQAQARQNQGTAPLNPYPGLTVTEPSFANPAGGYADGDLYPVGTSHPDWSGGLPNPLGNPSSQGGMIFDPNRRPAPRREDMPPGWMPGSKYDEPFGPGSGGFGGSGSGGFGGSGSGFI
What is the function of this protein?
Plays a role in the establishment of transcriptional silencing boundaries, preventing the propagation of heterochromatic silencing.
What are the official names of this protein?
Silencing boundary-establishment protein FUB1, Function of boundary protein 1, Proteasome inhibitor PI31-like protein FUB1.
What is the protein family that this protein belongs to?
Belongs to the proteasome inhibitor PI31 family.
Protein: RS4E_THEAC
Sequence: MINKTKRLMVSRQVKIPRKTYFWGPTPNPGMHPKDQSVTLLSIIRDYLKLSDKEREAARILANGLVKVDGKTVREKKFAVGFMDVIEINGESYRVVYNDQGALVLMKETKERASMKLLKVRSKVIAPGNRIQLGTHDGRTFITDDKSKKVGDVWAVSVPDMKISEIIKMQPGNKAYITAGSHVNQTGTISKIEAKEGSSANLVHFQEGFSTIKDHVFMIGSSKFSFVLSPEEVIP
What are the official names of this protein?
30S ribosomal protein S4e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
Protein: YIDZ_SALTY
Sequence: MKKSLTNLDLNLLLCLQLLMQERSVTKAAKRMNVTPSAVSKSLAKLRAWFDDPLFVNTPLGLAPTPLMVSMEQSLADWMQMGNQLLDKPHHQTPRGLKFELAAESPLMMIMFNSLSQQIYQRYPQATIKVRNWDYDSLEAITRGEVDIGFTGRESHPRSRELLSLLPLAIDFEVLFSDLPWVWLREDHPALREAWDLDTFLRYPHISICWEQSDTWALDDVLQEMGRKRHIALSLPGFEQSLFMAAQPGHTLIATAPRYCQHYNQLHQLPLVARPLPFDAQQREKLMVPFTLLWHKRNSHNPKIVWLRQAINTLCRRLI
What is the function of this protein?
Involved in anaerobic NO protection.
What are the official names of this protein?
HTH-type transcriptional regulator YidZ.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: ILVC_ACIBT
Sequence: MQIFYDKDCDLSIIQSKKVAIIGYGSQGHAHALNLKDSGVDVTVGLRAGSASWKKAENAGLKVAEVPAAVKQADLVMILTPDEFQSQLYRDVIEPNIKEGATLAFAHGFSVLYNQVVPRKDLDVIMVAPKAPGHTVRSEFQRGSGVPDLIAIHQDASGNARNVALSYASGVGGGRTGIIETSFREETETDLFGEQAVLCGGAVELVKMGFETLVEAGYAPEMAYFECLHELKLIVDLMFEGGIADMNYSVSNNAEYGEYVTGPEVINEQSREAMRNALKRIQSGEYAKMFIQEGALNYPSMTARRRQNAAHGIEQTGAKLRAMMPWIQANKIVDKEKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: Y2405_BORA1
Sequence: MNLPDTLLPCQRPRERLLRLGAPLLNDAELLALCLRTGRHGCNALELAQRLLTRHGGLRGIFALSAQELCTEPGLGVAKACSLLVAPELSRRSIEETLLGRQAMKHPEEVRRYCLTALAHQPVEHCIALYLDQQLQLLACGELERGTLGRASVFPREVVREALRLHAGAIILAHNHPSGNPQPSAADCAFTQQLSQALALVDIRLVDHIIVARDQALSMAERGLI
What are the official names of this protein?
UPF0758 protein BAV2405.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.