PharMolix/UniProtQA huggingface dataset:
Protein: RPOB_HETAK
Sequence: MVNNTFITKLPDFLEIQRSSFCWFLLKGLSYELNSLSPIIDVNVKRVKLKLYPQEFVLKPGRTTPICAKQNDSTYGVRIFLPAEVIYCDTESKYPTKKNRLEDIKEKVFIGQIPLMTSTGSFIVNGCEGYRNQIIRCPGLYYKAEFLNNNIVSTVTIIAQRGSWLKFEFDKNGYWVRIDKEKKISIFDFLEGLNINDEEILSGLKSIAPLLKYKKTQEILKRNNDPDLKNLIEKITDPNSYSLGIIGRLNLNRRLGLNISTRVHTLTIHDIFGIIDFFLSARSFVPDDIDDLRNRRIRAVGELITSQCEIGLNRLERNILERTNFSGSVRILPKTLVNARPIMSAIQEFFNSSQLSHYMDQTNLLSETANKRRISALGPGGLNADRVTVAARDIHPTQYGRLCPIETPEGQNVGLVSTLASYARINRNGFIQTPYFRVENGKILTQQPLIYLTAEQENLKIAPADVKRDQDGYLVDDFIVTRFQSKNFIITPSKLVDFISVSEIQIISVAASLIPFLEHDDANRALMGANMQRQAVPLLYPRKPIVGTGIESQVAFDSRLVNIATKPGIVKYVSSQQIDIKNIEGEKIAYKLIKYRPSNQDTCLNQRPLVWVGQSIKTGQVIADGPGTQSGELALGQNLTVAYMPWQGYNYEDAILVSDKLDIQNLFTSIHIEECETEVQQTKTGEQVITSDIPLVSEKNCKNLDENGIIKVGKYVYPGDILVGKITPKGEIDQLPEAKLLKAIFGFKTPDMRDSSLRVPGGLSGRVLDIKIFKKPKPGKVFGVGSKIRVFIAQISKLQVGDKIAGRHGNKGVISRILPHQDMPFLPDGTSVDIILNPLGVPSRMNVGQIFECLLGLAGDQLNKRFKILPFDEMYQNEASRILINQKLKDAAKKQNKPWLFSAYSPGKILLSDGRTGEKFDNPVLVGRSYILKLAHLVEDKIHARSTGPYSLITQQPVGGKSQNGGQRFGEMEVWALEAFGAAYTLQELLTIKSDDMQGRDDVLNSIVCGQEIPKSSIPESFKVLMRELNALGLDITTYKVMFENETNKNCLIKNEINLMQTYEEGIKAKIREEEKEREKEREAREMEDPEKIVSKIDAKQKKKYKKTKKQTEKKK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CCPR_CRYNH
Sequence: MSFRAPNLIRSTVGRRAGQTLNLRSQVIRRRFATEGGPEITKPSAPRSSNTGYIFAGLGVAAVGAAYYFYGTGRTEHDSTNKADTVVREAVATVEAKTGLRRGKDEYQKVYNRIAETLDKEGYDDGSLAPVLLRLAWHASGTYSKADGTGGSNFATMRFKPEAEHSANNGLHVAREHMEKIKQEFPWISYGDLWTLGGVCAIQESGGPTIPWRPGRIDGYAAQVTPDGRLPDATQAQDHLRFIFNRMGFNDQEIVALSGAHAMGRCHPNRSGFDGPWTFSPVTFSNQYFALLRDEPWQWKKWTGPAQFEDKKTKTLMMLPTDMALVKDKSFKKYVDIYADNEEKFFSDFAKAFSKLIELGVPERQWAGEPWTMATSD
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Cytochrome c peroxidase, mitochondrial, CCP.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: HBAD_AYTFU
Sequence: MLTAEDKKLITQLWEKVAGHQDDFGNEALQRMFVTYPQTKTYFPHFDLHPGSEQVRGHGKKVAAALGNAVKSLDNISQALSELSNLHAYNLRVDPVNFKLLAQCFQVVLAAHLGKDYTPDMHAAFDKFLSAVAAVLAEKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-D, Alpha-D-globin, Hemoglobin alpha-D chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: YOHJ_SHIB3
Sequence: MSKTLNIIWQYLRAFVLIYACLYAGIFIASLLPVTIPGSIIGMLILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAVCTLVVFLVVSWSSQLVHGERKVVGQKGSEE
What are the official names of this protein?
UPF0299 membrane protein YohJ.
What is the protein family that this protein belongs to?
Belongs to the UPF0299 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: C4_ORYSJ
Sequence: MAASKGNAAAAACALVLVLLAVGAEAQGGGGGECVPQLNRLLACRAYAVPGAGDPSAECCSALSSISQGCACSAISIMNSLPSRCHLSQINCSA
What is the function of this protein?
Lipid-transfer protein that may be regulated by the transcription factor UDT1 in developing anthers and play a role in tapetum development.
What are the official names of this protein?
Non-specific lipid-transfer protein C4, OsC4.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: ENGB_RHIE6
Sequence: MPETEKPLFGHPWIFIRGVPSLTFLPPEGPSEVAFAGRSNVGKSSLINALVGQKGLARTSNTPGRTQELNYFVPDGYSGEGGDLPPMAIVDMPGYGYAQAPKEQVDKWTKLVFDYLRGRATLKRVYVLIDSRHGIKKNDEDVLTLLDKAAVSYQLVLTKTDKIKAPAVPKLLAETADKIRKRPAAYPAVLSTSSEKGDGLDDLRQAIAQTVGIANWE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: G6PI_YERPN
Sequence: MKNINPSQTAAWKALQQHFEQMKDVTISSLFAKDDQRFNRFSATFDDQMLVDFSKNRITSETLEKLQDLAKETDLAGAIKSMFSGEKINRTEDRAVLHIALRNRSNTPIVVDGKDVMPEVNAVLAKMKQFCDRVISGDWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPYKNHLNMHFVSNVDGTHIAEALKPLNPETTLFLVASKTFTTQETMTNAHSARDWFLSAAGDPAHVAKHFAALSTNAKAVGEFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALSVGFEHFEQLLSGAHAMDKHFAETPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFPAYFQQGNMESNGKYVDRNGHPVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKLIPCDFIAPAISHNPLSDHHAKLLSNFFAQTEALAFGKSLEDVEAEFAAAGKTPEQVAHVAPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIYTFDQWGVELGKQLANRILPELADDQEVTSHDSSTNALINRFKNWR
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_COREF
Sequence: MPGRERRDGGRSADENKSNDRNERRGGGRRDDRRNQQQDERSQYIERVVTINRVSKVVKGGRRFSFTALVIVGDGQGMVGVGYGKAKEVPAAIQKGAEEARKNFFRVPMVGGTITHPVQGEAAAGIVMLKPAAPGTGVIAGGAARPVLECAGIQDILSKSLGSDNAINVVHATVDGLKQLVRPEEVAARRGKTVEEVAPARILRARAGQEA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: PSBH_TRICV
Sequence: MALRTRLGEILRPLNAEYGKVAPGWGTTPIMGVVMLAFLVFLLIILQIYNSSLIIENVDVDWSNGIV
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: FTSK_SHIFL
Sequence: MSQEYTEDKEVTLTKLSSGRRLLEALLILIVLFAVWLMAALLSFNPSDPSWSQTAWHEPIHNLGGMPGAWLADTLFFIFGVMAYTIPVIIVGGCWFAWRHQSSDEYIDYFAVSLRIIGVLALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHSSGGTIALLCVWAAGLTLFTGWSWVTIAEKLGGWILNILTFASNRTRRDDTWVDEDEYEDDEEYEDENHGKQHESRRARILRGALARRKRLAEKFINPMGRQTDAALFSGKRMDDDEEITYTARGVAADPDDVLFSGNRATQPEYDEYDPLLNSAPITEPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPSQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAVSPLASGVKKATLATGAAATVAAPVFSLANSGGPRPQVKEGIGPQLPRPKRIRVPTRRELASYGIKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQHDVPVNAEDADAAAEAELARQFAQTQQQRYSGEQPAGANPFSLDDFEFSPMKALLDDGPHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVAPQQQYQQPQQQVAPQPQYQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQDTLLHPLLMRNGDSRPLHKPTTPLPSLDLLTPPPSEVEPVDTFALEQMARLVEARLADFRIKADVVNYSPGPVITRFELNLAPGVKAARISNLSRDLARSLSTVAVRVVEVIPGKPYVGLELPNKKRQTVYLREVLDNAKFRDNPSPLTVVLGKDIAGEPVVADLAKMPHLLVAGTTGSGKSVGVNAMILSMLYKAQPEDVRFIMIDPKMLELSVYEGIPHLLTEVVTDMKDAANALRWCVNEMERRYKLMSALGVRNLAGYNEKIAEADRMMRPIPDPYWKPGDSMDAQHPVLKKEPYIVVLVDEFADLMMTVGKKVEELIARLAQKARAAGIHLVLATQRPSVDVITGLIKANIPTRIAFTVSSKIDSRTILDQAGAESLLGMGDMLYSGPNSTLPVRVHGAFVRDQEVHAVVQDWKARGRPQYVDGITSDSESEGGAGGFDGAEELDPLFDQAVQFVTEKRKASISGVQRQFRIGYNRAARIIEQMEAQGIVSEQGHNGNREVLAPPPFD
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination.  FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation.  FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif (By similarity).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Located at the septum.
Protein: SECB_PARDP
Sequence: MSDENNSGAAAPEAQNPGQNAAQPAVRLQILTQYIRDLSFENAVAQKGLPSGEVQPEISVQVSLDARKRPAEHQYEVISKFRVQSSNATDKSPLFLCELDYGGIFHVEGVPEDQLHPFLMIECPRMMFPFVRRIVSDMTRDGGFPPFNMDPVDFVALYRQEIARRTQAQRPADQPLS
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_BEUC1
Sequence: MANYTAADIKTLREKSGAGMLDVKKALDEADGDAEKALEIIRVKGLKGVAKREGRSASEGLVAVKVTDAHDVAGQVGTMVELNAETDFVAKNATFVGLAERVLDAAVASAARDADALLAADAGGETVAEIVDGAAATLGEKLVLRRVARLDGEHVGVYLHRTSKDLPPQVGVMVATDAAAASVAEEIAMHVAAYSPAYLTREDVPEQLVADERRIAEETARNEGKPEQALTKIVEGRLNGFFKDQVLVDQAFARDPKKTVGQVVAETGGTLTGFARFRVGA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_PROM9
Sequence: MQYQIERIDHQIADDRSQTGTFLIGPLERGQATTLGNSLRRVLMGGLEGSAVTAVRIAGINHEYATIPGVREDVLDILLNCKQLSINSSNPELEIGRLVASGPLDVKANDIQFSSQVEIVDGEKPIATIQEGHNLELEIHVERGVGYRPVDRKNQETTAIDLLQIDAVFMPVKRVNFSIDETAVAEGGTGRERLKMEVVTDGSTSPDDAIAEAANQLIELFQPLATVTMVEEIPEEPEPSPEAQIPLEELNLSVRAYNCLKRAQVNSVSDLMGFSYEDLLEIKNFGSKSADEVIEALERIGISIPQSRTSV
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: DAPE_YERPG
Sequence: MICPVIELAQQLIKRPSLSPSDAGCQEIMIQRLAAIGFTIEPMNFGDTLNFWAWRGEGETLAFAGHTDVVPTGDESHWHSPPFEPTIRDGMLYGRGAADMKGSLAAMIVAAERFVAAHPDHKGRLAFMITSDEEAKATNGTVKVVEALMARHERLDYCLVGEPSSTDRVGDIVKNGRRGSITANLRIHGVQGHVAYPHLADNPVHRAMPALNELVATQWDEGNAFFPATSMQIANLQAGTGSNNVIPGEFYVQFNFRFSTELTDSLIKQRVAALLDRHQLDYTLEWVLSGQPFLTAKGALVDAVVNAVKHYTEITPQLLTTGGTSDGRFIALMGAQVVELGPVNATIHKVNECVSAADLQLLSRMYQKIMEQLIA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: FOLD_LEGPL
Sequence: MPASLIDGREISALRRTELKQRVQYHVEQGQRAPGLAVVLIGNDPASVIYVSNKRKACEEVGITSHSYDLPAETTQEKLIELINELNQSDKIDGILIQLPLPKHINERTIIEHIKPEKDVDGFHPYNLGRLAQRNPFLRPCTPLGIMNLLHHYELNVKRKHAVVIGASNIVGRPMSLELLLAGATVTICHKFTQQLQKFVEIADFLIVATGKMDVIATDWLREHQVVIDVGMHRLPDGSIRGDIDFKKAVEKVAWITPVPGGVGPMTIVTLLENTMMSAARLRE
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: FTHS_CERS5
Sequence: MTFQSDIEIARAANKLPIQEIGARLGIPSGDLIPYGHDKAKVSQGFIRGLADRPDGKLILVTAINPTPAGEGKTTTTVGLGDGLNRIGKRAVICIREASLGPNFGMKGGAAGGGRSQVVPMEDMNLHFTGDFHAITSAHNLLSAMIDNHIYWGNDLGLDARRITWRRVMDMNDRALRDMVVNLGGVSNGFPRQTGFDITVASEVMAILCLAEDLEDLERRLGGIVVGYRRDRSPVFCRDLKADGAMAVLLKDAMQPNLVQTIENNPAFVHGGPFANIAHGCNSVIATRTALKLADYVVTEAGFGADLGAEKFFDIKCRKAGLKPSAAVVVATVRALKMNGGVAREDLGREDVAALKRGCANLGRHIANVKGFGVPVVVAINHFTTDTEAEIEAVRAYAAGQGAEAILCRHWADGSAGIEDLARKVVQLAETPSMFAPLYPDEMPLFEKMETVARRIYHAHDVIADHVIRDQLRAWEDAGYGALPVCMAKTQYSFTTDAAIRGAPEGHSVPIREVRLSAGAGFVVAICGEIRTMPGLPREPAAEVIRLNGEGRIEGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: SYC_DESPS
Sequence: MDIRVYNTLSGKKEPLQPIEPNHVKLYVCGITSYDYCHIGHARSALAFDMIVRYLRYLDYKVTFVRNFTDIDDKIIARANETGVTAQALAERFIDEFHTDMDNLGTLRPDIEPKATEHIQEMIDIIQELVDKDMAYPSAGDVYYVVNSFPEYGKLSGRNIEDMQAGARISINEQKRNPMDFALWKASKPGEPSWESPWGPGRPGWHIECSAMSRKYLGENFDIHGGGKDLIFPHHENEIAQSEGANGKPFANTWIHHGFVTIKDEKMSKSLGNFLTIKDILDHYHPEILRAFIFSTQYRNPLDFSEIAMQDAETALVRLYECLHDIQQLAKGDPTLPALISAKDAAKLNSIETRFQEAMNNDFNTALALGVLYDAIKIINRAQRALTDTPSALDVKMLKGSMTLIQKLAGIVGLLQEDANLFLQQRKEKMLSGIDITEAEIESYIQQRLDARANKDWARSDEIRDILLEKGITLKDGADGTGWSVHRAN
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_PYRAR
Sequence: MNTFGRELRITTFGESHGRAIGVVIDGVPAGLPLTEEDIRKELDRRMFCHIHWLNPRCEPEEFEILSGVKDGHTQGTPIAIVIWNKKAISSYYDELWMKPRPGHADLAYYLKYGKFYDHRGGGRASGRTTAAIVAAGAVAKKLLALVGAEVAGHIVELGGVEVKRPYTFEDVKKSWEKPLPVVDDDALAAMLEVLRKNAAEGDSVGGGVEIWAVGVPQGLGEPHFGKIRADLAHAAFSVPAVVALDWGAGRQLAKMRGSEANDPIVVKGGKPGLETNKIGGVLGGITIGEPLYFRVWLKPTPSVRKPQRTVDLAKMEPATLQFKGRYDVSVVPKALVALEAMTAITLADHLLRAGVIRRDRPLKDPVV
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: PANB_IGNH4
Sequence: MKKVTIRDIMKKYKNGEKIVMVTAYDYPFAKLVDEAGVDMILVGDSLGMVVLGYPSTNQVTMKDMLHHVAAVARANPKAMIVGDMPFGSYEVSEEEAVRNAVELVRAGAEAVKLEGGKEVADKVEAIVKAGIPVMGHLGLTPQKRHALGGYRLRGKTEEEARELLEDAKALEEAGVFSIVLEFVKAEVAKKITEEVGVPTICIGAGPWCSGQVLVIHDILGLAPFSPPFAKKYFDCGKAIVEAVKKFAEEVRSGEFPGEGYYW
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEN_PYRFU
Sequence: MGVPIGEIIPRKEIELENLYGKKIAIDALNAIYQFLSTIRQKDGTPLMDSKGRITSHLSGLFYRTINLMEAGIKPVYVFDGEPPEFKKKELEKRREAREEAEEKWREALEKGEIEEARKYAQRATRVNEMLIEDAKKLLELMGIPIVQAPSEGEAQAAYMAAKGSVYASASQDYDSLLFGAPRLVRNLTITGKRKLPGKNVYVEIKPELIILEEVLKELKLTREKLIELAILVGTDYNPGGIKGIGLKKALEIVRHSKDPLAKFQKQSDVDLYAIKEFFLNPPVTDNYNLVWRDPDEEGILKFLCDEHDFSEERVKNGLERLKKAIKSGKQSTLESWFKR
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity.  Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation.  Also involved in the base excision repair (BER) pathway.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
Protein: MRAZ_COLP3
Sequence: MFRGTSAITLDSKNRITIPTKYREELFADCQGKMVCTVDIQHPCLLLYPLPEWEEIELKLCNLSSMNPQERLLQQVILGNASDCEMDKNGRLLINGPLRQHASLEKNVMLVGQLKKFEIWHDTAWQSQMLQGISKIQSGEIELTERLLDLSL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: HDFR_SHIDS
Sequence: MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTAAGEKLLPYAETLMSTWQAARKEVAHTSRHNEFSIGASASLWECMLNQWLGRLYQNQDAHTGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQLLGYFTLALYTSAPSKLKGDLNYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQIAMLNGCTWLPVSWARKKGGLHTVVDSTTLSRPLYAIWLQNSDKNTLIRDLLKINVLDEVY
What is the function of this protein?
Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
What are the official names of this protein?
HTH-type transcriptional regulator HdfR, H-NS-dependent flhDC regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: GSPB_ECOLI
Sequence: MFEFYIAAREQKETGHPGIFSRQKHSTIIYVICLLLICLWFAGMVLVGGYARQLWVLWIVKAEVTVEAETPAFKQSTQHYFFKKQPLPVVESVEEEDDPGVAVENAPSSSEDEENTVEESEEKAGLRERVKNALNELER
What is the function of this protein?
Part of a cryptic operon that encodes proteins involved in type II secretion pathway in other organisms, but is not expressed in strain K12 under standard laboratory conditions (PubMed:8655552).  May play a regulatory role under conditions of derepressed gsp gene expression (PubMed:11118204).
What are the official names of this protein?
Putative general secretion pathway protein B.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: DUT_ERWT9
Sequence: MMKKIDVKILDARVGTDFPLPTYATSGSAGLDLRACLNEATVLQPGATTLLPTGLAIHIADPQLAAVILPRSGLGHKHGVVLGNLVGLIDSDYQGPLMVSVWNRGQDSFTIEPGERIAQMVFVPVVQAEFNLVNDFDASVRGEGGFGHSGRQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: SECD_METKA
Sequence: MSGLGWMKENWRLLVITAVWIVAATSLAVKGVNLGLELKGGTMVIAKTDHPVSKKEMDQTVTVLESRLSTFGFKGIKIQPVGRDHIIVMLPGTPPKEAVELITKPGRFEAKYKGKTVITGQDIESVESPRIERVEGGYQWSVPFRLTAEGARKFAEVAKNAPGQPIDMYLDNKKVSSPRISEDLAMAAASGHMEREIEIVGGAKTKEQAEREAKEIMAVLRSGQLPAKLVPEGVYSVSATLGQNFLKMAMIAGAIAFAAVSVIIALRYRDIRISGPILFTGSSEVVFLIGLASLTGFTIDLPALAGIILSIGSGVDDLIVITDEIVRGERRKEEVTLRQRIKRAFSVVLASFATLAAAMAVLFVAGMGLLKGFAIMTIAGAFYGVVITRPVYADLLKKILGTE
What is the function of this protein?
Involved in protein export.
What are the official names of this protein?
Protein-export membrane protein SecD.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecD subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRMB_SCHPO
Sequence: MSATAKKSAAQLQREEEEARKKLKRLSKQGGVEGRLPMKRLFRQRAHANVLSDHELEYPRSPSEMDWSPYYPDFDVESNKKVEIVDIGCGYGGLTVALGPQFPDTLVLGMEIRMQVSDYLKEKIQALRYRADHEEPVPGGYKNISVLRMNCQKFLPNFFEKGQLSKMFFCFPDPHFKARKHKNRIITSTLASEYAYFIRPHGTLYTITDVEELHVWMAQHLDAHPLFRRFTKEEEENDICVTLMTNETEEGKKVARNGGKKFVACYERIPNPK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, Transfer RNA methyltransferase 8, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VG26_BPML5
Sequence: MPNSAGVEVARISVKVSPNTKEFRRELKTELEKIERELKGDVEINGHLDAAQAKADFKRMMMQLKTEAAKGVHVPVDVTVDKKSKKGGLLGGLLGGSRGLGDLGDDAEKASSQVQHLGKSFLGLTRAAWIGVGIVAVAAPLVGIVAGLLAGLPSLLSAFGAGAGVVALGMDGIKAAASTLAPTLETVKAAVSSTFQQGLTPVFQQLGPMLTAITPNLQNVASGLVNMAGSITDVITQAPGLQQIQNILTKTGEFFTGLGPVLATGTQAFLTLSNAGANSFGTLLAPLQEFTNGFNDMVNRVTSNGVFEGAMQGLSQTLGSVLNLFNRLMESGLQAMGQLGGPLSTFINGFGDLFVSLMPALTSVSGLIGNVLGTLGTQLAPIVTALTPAFQTLASTLGTMLTGALQALGPILTQVATLIGTTLNTALQALQPMLPSLMQSFQQISDVLVTSLAPHIPALATALGQVAGAVLQLAPTIISTLVPAFVQLVPKVAELVPTIVNLVQSFANLMPVVLPLAQALVSVAGAVIQVGVSIGGALIGALANLTEIISNVIKKVSEWVSSFSSGAQQIAAKAAELPGMIQSALANLMAIGLQAGKDLVQGLINGIGGMVSAAVNKAKELASSVAGAVKGFLGIESPSKLFTEYGQFTAEGFGNGMEAGFKPVIERAKDLAAELSRAMESGTDPSGILAGLDQNELKQMLAALEEERKRLKVEKNGIPKGDKAGREALQNQLDQIQAQKDILSYQRDRIKNESEYGDMAGEDPLVKAASGLMSAPVDFAKATGKQFLSDIGISGDGFISKAITEGIQYIFQIGSVDEALSIKDREESKNALSVVGR
What are the official names of this protein?
Minor tail protein Gp26.
Protein: UPP_PSEU2
Sequence: MPIREIRHPLIRHKLGLMRRADISTKNFRELAQEVGALLTYEATADLTLENYDIQGWAGTVSVEKIAGKKITVVPILRAGIGMLDGVLSLIPGAKVSAVGVARNEETLQAHTYLEKLVPEIDERLAMIIDPMLATGSSMVATIDLLKKAGCKEIRAMVLVAAPEGIAAVEKAHPDVMIYTASIDERLNEHGYIIPGLGDAGDKIFGTKQKDA
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.