PharMolix/UniProtQA huggingface dataset:
Protein: MP2K5_HUMAN
Sequence: MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAFEYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGLKVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVSMWVCRALEERRSQQGPP
What is the function of this protein?
Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex.  Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis.
What are the official names of this protein?
Dual specificity mitogen-activated protein kinase kinase 5, MAP kinase kinase 5, MAPKK 5, MAPK/ERK kinase 5, MEK 5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
Protein: RECR_BRUA2
Sequence: MSKRIAGPEIERLIQLLARVPGLGPRSARRAALHLIKKKEALLVPLGGAMQEAAEKVRICSCCGNVDTSDPCTICTDERRDPATLIVVEDVSDLWALERAGTMNVRYHVLGGRLSPLDGIGPDDLNIKGLVERVASGAIKEVILAVNATVEGQTTAHYITDQLSNFDVRVTRLAHGVPVGGELDYLDEGTLAAALRARTTL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RSZ32_ARATH
Sequence: MPRYDDRYGNTRLYVGRLSSRTRTRDLERLFSRYGRVRDVDMKRDYAFVEFSDPRDADDARYYLDGRDFDGSRITVEASRGAPRGSRDNGSRGPPPGSGRCFNCGVDGHWARDCTAGDWKNKCYRCGERGHIERNCKNSPSPKKARQGGSYSRSPVKSRSPRRRRSPSRSRSYSRGRSYSRSRSPVRREKSVEDRSRSPKAMERSVSPKGRDQSLSPDRKVIDASPKRGSDYDGSPKENGNGRNSASPIVGGGESPVGLNGQDRSPIDDEAELSRPSPKGSESP
What is the function of this protein?
Probably involved in intron recognition and spliceosome assembly.
What are the official names of this protein?
Serine/arginine-rich splicing factor RS2Z32, RS-containing zinc finger protein 32, At-RS2Z32, At-RSZ32, AtRSZ32, Serine/arginine-rich splicing factor RSZ34, AtRSZ34.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family. RS2Z subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: FLIW_DECAR
Sequence: MKVETYLFGAVDVSPEKVITFPNGLVGFEQSKRYMLVHEEGPAEPSSFTLQSLDDPMLAFQIVDPVMLGFNYELALSDAENALLQSPSPEDVAVMQVLFRKEQDDKGSITPNLRAPLVINTKSRVGLQKVMETMRPNITLSNLSSSI
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METAA_STRMU
Sequence: MPITLDKKLPAVDILKSENIFVMDDKRAIHQDIRPMSILILNLMPTKVATETQLLRLLANTPLQLSVDFLYMTSHHSKTTQAEHMKTFYKTFKDIKDNYYDGLIITGAPVETMPFEKVDYWEELCQVFQWSKTHVYSTLHLCWGAQAGLYYRYSVDKVQMTDKLSGIYLQKVNEQLSPLMRGFDDCFLSPHSRYTEVLLKDINNKTNLEILASGEKVGLSILASRDMREVYSFGHLEYDRETLDNEYKRDLKAGKSPKIPENYYQDDDVTTHPIMRWNLAAATFFSNWINYAVYQETPYRLEELEKDISFYGYL
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAP1_GROCL
Sequence: MKVSSAIALLLPVVAARFVDSAFEQDHVQLHPEQAAAEQFLIELSPGETRWVTEDEKWELRRNGQRFMDITDNRDLGLASAQSATTGPARVFPPNVTLDEEVFPLLANLSKGELQTHLEKLTSFHTRYYRSEHGRASSNWLLGQVKKTVGEAGGFKHGITVKPFKHPWGQNSVIARIPGQTNRTIVVGAHQDSINLFLPSVLSAPGADDDGSGTVTILEALRVLLQSEAVLAGKAANTIEFHWYSAEEGGLLGSQAIFNTYEKASRDVRAMLQQDMTGFVQRTLDAGEVESVGVIVDYVDPGLTAFIKKVITAYCDIPFIETKCGYACSDHASASKAGYPSAFVIESAFERSDDHIHTSDDLIKYLSFDHMLQHARLTLAFVYELAFADFDKLDKAAAVSVAPEMGDL
What is the function of this protein?
Extracellular aminopeptidase that allows assimilation of proteinaceous substrates.
What are the official names of this protein?
Leucine aminopeptidase 1, Leucyl aminopeptidase 1, LAP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28E subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL23_BACCN
Sequence: MRDPRDIIKRPVITERSMEMMAEKKYTFDVDVKANKTEVKDAVEAIFGVEVEKVNIMNYKPKAKRVGRHAGFTNRRRKAIVKLTADSKEIEIFQGV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: USPB_SALPK
Sequence: MISTVSLFWALCVVCIVNMARYFSSLRALLVVLRGCDPLLYQYVDGGGFFTTHGQPNKQVRLVWYIYAQRYRDHHDEEFIRRCERVRRQFLLTSALCGLVVVSLIALMIWH
What are the official names of this protein?
Universal stress protein B.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LOLC_BUCAP
Sequence: MYKPIYIFIGLRYLWNPYLPNFKKIIIILSILGIGIGISSTIITISIMNGFQNKFKNDILSFIPHIIITNKNRNINKLNFPKETLKLKNVEEITDFISKKVIIENKNEINIGEIIGINIKNEKNLENYNIKKFLHTLHSRKYNAIIGSELAKKMHVNINDQIKLIVLPISKKKFLQNDLNIKLFKITGIFSTNSEIDEYQILINKKNALNFLNYNKNYITGWKIKLKDPFILNIQKIKKLNKNFIILDWKTKKGELFKAMKIEKYIMLFFFILILLVSSFNIVISLTMNVLDKKNNISIFQSQGLSRYKIMLIFIILGSTISIVGNSFGTIISIILIFQKDFLNFLIKIFFIDIEIPIEISLIQILTINITFIFLTILSTLYPIWYAIKSTPSRILSDE
What is the function of this protein?
Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane.  Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of LolA (By similarity).
What are the official names of this protein?
Lipoprotein-releasing system transmembrane protein LolC.
What is the protein family that this protein belongs to?
Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PROB_RUEPO
Sequence: MATLTTARRLVVKIGSALLVDRNTGDLRADWLHSLAADVAWLKGLGLDVILVSSGSIALGRGVLGLPRTALPLEQSQAAAAVGQIRLARAYEEALAPHRITTAQVLVTLEDSEDRRRYLNSRATLETLLGLGAVPIVNENDTVATDEIRYGDNDRLAAQIAVTVGADQLILLSDVDGFYTGNPSDDPGATRFDVIDRITPEIVAMAGDAGSGLSKGGMKTKLMAAQMATAGGCAMAITEGSPLNPLKTLENGANCTWFTATLDPQAARKRWIAAMKPRGDITVDAGAARALEGGKSLLPAGVASVTGDFGRGDPVAILGPDGRRLGQGLCRYTGDEARAIRGRQSSDIEATLGYPGRAALIHRDDMAL
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_XYLFT
Sequence: MTKPIRNVAVLGATGSIGAAALDVLARHPRQFHVSLLAAGQRVDALLALCRTYRPDHAVIGDATLYTTLRDGLNAAGLATKAYAGEAALAELVASTTCDTVVAAIVGAAGLHSTLAAARAGKRLLLANKESLVLAGMLLMREASISGAEIIPIDSEHNAIFQCLRSRTTDGVHRVTLTASGGPFRGHNRTMLAKITPTQAMAHPTWSMGPKISVDSATLMNKGLEVIEAHHLFGLPSEQIDVLVHPQSLVHSLVEFIDGSTLAQLSLPDMRTTLAVGLAWPERIGSGVQGLDLMKHNRLDFEHPDTETFSCLRLARDAMQTGGTAPAVLNAANEIAVSAFLQGRIGFLTIPALIEHALTTLPRYEADTLETLLTVDTETRRITHAALTHFPLPL
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: EMC4_XENTR
Sequence: MATPSNLVANRGRRFKWAIEFGSGGSRGRGERGGLQDSMYPVGYSDKQVPDTSVQESDHILVEKRCWDIALGPLKQIPMNLFIMYMAGNTISIFPIMMVCMMAWRPIQALLATPATFKLLESSGQRFLQGLVYLIGNLLGLALAVYKCQSMGLLPTHASDWLAFIEPPERMEYTGGGLLL
What is the function of this protein?
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.  Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues.  Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices.  It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes.  By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors.  By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes.
What are the official names of this protein?
ER membrane protein complex subunit 4, Transmembrane protein 85.
What is the protein family that this protein belongs to?
Belongs to the EMC4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TCMJ_STRGA
Sequence: MTTAQHEGEQTVAAAAKIAMSSVAPSHRQGGSTRALLTPSSVGATSGFLGHIELAPGESVTEHYHPFSDKYLYLIEGSLVVRVNGEEVRLERDEALFVTRGQRHRIENRGNVPARVVFQISPLAPRPELGHVDTEPVPNPAAAPPKVGG
What is the function of this protein?
Involved in the biosynthesis of tetracenomycin C (TCM C) (PubMed:8244926, PubMed:9609708).  Part of a type II polyketide synthase (PKS) that catalyzes the synthesis of tetracenomycin F2 (TCM F2), a precursor of TCM C, from malonyl-CoA (PubMed:8248801).  TcmJ, while not absolutely required, greatly increases the tetracenomycin F2 production (PubMed:8244926, PubMed:8248801, PubMed:9609708).  It probably acts as a cyclase (PubMed:8244926, PubMed:8248801).
What are the official names of this protein?
Tetracenomycin polyketide synthase protein TcmJ, TCM PKS.
Protein: RHOJ_MOUSE
Sequence: MSCRERTDSSCGCNGHEENRILKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVGGKQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKDCMPHVPYVLIGTQIDLRDDPKTLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALTQKGLKAVFDEAILTIFHPKKKKKGCLGCHGCCAII
What is the function of this protein?
Plasma membrane-associated small GTPase specifically involved in angiogenesis (By similarity).  Required for endothelial cell migration during vascular development via its interaction with GLUL (By similarity).  Elicits the formation of F-actin-rich structures, thereby regulating endothelial cell migration (PubMed:10967094).
What are the official names of this protein?
Rho-related GTP-binding protein RhoJ, Tc10-like GTP-binding protein.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Note=Localization to the plasma membrane is regulated by GLUL.
Protein: PPK19_DROME
Sequence: MLLYTKELVIPRPRPGLLRFRNNPRGIKFREKLCNSFAHSNIHGMQHVFGEQHLWQRCLWLAIVLGAVITGFSLYTVLMHRHSEQLLVSLIETTQLPVYHIDFPAVAVCPWNHFNWQRAPSAFIRFLPRHPNAELRETFRQLLASMDIMNFSNFNRIRILTKRNLTGISYLKMTDLMNFMTYRCDELFVADSCVFDETPYDCCKLFVREQTVKGQCLVFNSMISENSRKKHLINQFYPHKLSTAGEDSGLKFTINASYSFMNNIDALTPFGMNLMIKEPRQWSNEMMYHLYPDTENFVAVHPLVTETSPNTYEMSPKKRRCYFDDEKNPTFQNTSLTYNRENCLVVCLHLVVWKTCQCSLPAFLPPIDGVPECGINDAQCLGNNSDIFTYVKMGDQEKYINDSRQGHFCDCPDNCNSRLYEMSLNVRKLDYPKNSTDQLIKAQVYYGQRVMTKIITKLKYTNIDLLANFGGIISLYIGASVMSFIELLFVLGKLMWGFIRDARIKLKEYTK
What is the function of this protein?
Part of a complex that plays a role in tracheal liquid clearance.  In both larvae and adults, contributes to the behavioral response to salt.  Probable role in sodium transport.
What are the official names of this protein?
Pickpocket protein 19, PPK19.
What is the protein family that this protein belongs to?
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PLE1_PSEAM
Sequence: MKFTATFLMMAIFVLMVEPGECGWGSFFKKAAHVGKHVGKAALTHYLGDKQELNKRAVDEDPNVIVFE
What is the function of this protein?
Antimicrobial peptide with potent activity against Gram-positive and Gram-negative bacteria.  Activity against E. coli and B. subtilis.  Weaker activity against L. mucor, s. marcescens and P. aeruginosa.  May play a role in innate host defense.
What are the official names of this protein?
Pleurocidin.
What is the protein family that this protein belongs to?
Belongs to the pleurocidin family.
What are the subcellular locations of this protein?
Secreted. Membrane; Peripheral membrane protein. Note=Associates with phospholipid membranes via its amphipathic helix and can insert into the lipid bilayer.
Protein: PSBF_PHOTN
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVSFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: UBE2N_DROME
Sequence: MSSLPRRIIKETQRLMQEPVPGINAIPDENNARYFHVIVTGPNDSPFEGGVFKLELFLPEDYPMSAPKVRFITKIYHPNIDRLGRICLDVLKDKWSPALQIRTILLSIQALLSAPNPDDPLANDVAELWKVNEAEAIRNAREWTQKYAVED
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 N, E2 ubiquitin-conjugating enzyme N, Protein bendless, Ubiquitin carrier protein N, Ubiquitin-conjugating enzyme E2-17 kDa, Ubiquitin-protein ligase D3, Ubiquitin-protein ligase N.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: MURA_METNO
Sequence: MDRIHITGGAPLHGEIPISGAKNAALPLMIASLLTGETVELANVPRLADIASLLRILGNHGVDHMVVGKRPGQTAETGQTIRLTASNVIDTTAPYELVSTMRASFWVIAPLLARFGEARVSMPGGCAIGTRPVDLLLMAMERLGATIEIDGGYVVARTRNGLRGAEIVFPKVTVGGTHVALMAASLAQGTTVIDNAAREPEVVDLAECLSKMGARIEGAGTPRIVVEGVSRLGGARHEVLPDRIETGTYAMAVAMTGGDVILRDTRADLLHSALDVLATTGTEVTALPNGIRVRRNGAGVAAVDVTTDPFPGFPTDLQAQFMALMTKARGQSRIRETIFENRFMHVQELARLGARIRLEGDLAVVDGVERLRGAPVMATDLRASVSLVIAGLAAEGETIINRVYHLDRGFEALEAKLSRCGAQIRRERV
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MECA_STRR6
Sequence: MKMKQISDTTLKITISLEDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMSPDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFAKLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDSDISRSVLQEYGQVLMSHDAVLNLQKIG
What is the function of this protein?
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
What are the official names of this protein?
Adapter protein MecA.
What is the protein family that this protein belongs to?
Belongs to the MecA family.
Protein: RL154_PLAVT
Sequence: MRRCALLFRLFLISYSCSVYFSACTQASSLKEPDEELPRAEQWDDNGKRILQADDPEHIRTEERGITQNLKPAAESIGKVKAAGKAIKTSVLNSKLMNWVKTALRKGYTAWQLVKMYSLSKGGGVSAMMSGITPLTYKTVYGRTIASKVDVKEKFDTFKTEYFKLFEDLDNVKPSSGMQYWDDELKKLPWTRQFTARLALNKVRKILKSDPSVEKMIDLNVSPLLYMRALEKQGAFARNDVAAINKLKDYVKAFKKHVDLA
What is the function of this protein?
Secreted effector that completely suppresses the host cell death induced by cell death-inducing proteins.
What are the official names of this protein?
Secreted RxLR effector protein 154.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane.
Protein: HSP83_DROPS
Sequence: MPEEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELYIKLIPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLIADRVTVTSKNNDDEQYVWESSAGGSFTVKADNSEPLGRGTKIVLYIKEDQTDYLEESKIKEIVNKHSQFIGYPIKLLVEKEREKEVSDDEADDEKKDDEAKKDMDTDEPKIEDVGEDEDADKKDKDGKKKKTIKEKYTEDEELNKTKPIWTRNPDDISQEEYGEFYKSLTNDWEDHLCVKHFSVEGQLEFRALLFIPRRTPFDLFENQKKRNNIKLYVRRVFIMDNCEDLIPEYLNFIKGVVDSEDLPLNISREMLQQNKVLKVIRKNLVKKTMELIEELTEDKENYKKFYEQFSKNLKLGVHEDSNNRAKLADFLRFHTSASGDDFCSLSDYVSRMKENQKHVYFITGESKDQVSNSAFVERVKARGFEVVYMTEPIDEYVIQHLKEYKGKQLVSVTKEGLELPEDEAEKKKREEDKAKFEGLCKLMKSILDSKVEKVVVSNRLVDSPCCIVTSQFGWSANMERIMKAQALRDTATMGYMAGKKQLEINPDHPIVEALRQKADADKNDKAVKDLVILLFETSLLSSGFSLDSPQVHASRIYRMIKLGLGIDEDEPMTTEDAHSGGDAPGLVEDTEDASHMEEVD
What is the function of this protein?
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction.  Undergoes a functional cycle that is linked to its ATPase activity.  This cycle probably induces conformational changes in the client proteins, thereby causing their activation.  Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.  Required for piRNA biogenesis by facilitating loading of piRNAs into PIWI proteins (By similarity).
What are the official names of this protein?
Heat shock protein 83, HSP 82.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTD_YERPE
Sequence: MVTQATSVRWQLWIVAFGFFMQTLDTTIVNTALPSIAASLGENPLRMQSVIVSYVLTVAVMLPASGWLADRIGVKWVFFSAIILFTFGSLMCAQSATLNELILSRVLQGVGGAMMVPVGRLTVMKIVPREQYMAAMAFVTLPGQIGPLVGPALGGFLVEFASWHWIFLINLPVGVIGALATLLLMPNHKMSTRRFDISGFIMLAIGMATLTLALDGHTGLGLSPLAIAGLILCGVIALGSYWWHALGNRFALFSLHLFKNKIYTLGLVGSMSARIGSGMLPFMTPIFLQIGLGFSPFHAGLMMIPMIIGSMGMKRIIVQVVNRFGYRRVLVNATLLLAVVSLSLPLVAIMGWTLLMPVVLFFQGMLNALRFSTMNTLTLKTLPDRLASSGNSLLSMAMQLSMSIGVSTAGILLGTFAHHQVATNTPATHSAFLYSYLCMAIIIALPALIFNRVPPDTGANRHLAR
What are the official names of this protein?
Putative multidrug resistance protein MdtD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THII_SULIK
Sequence: MLIIIRPSGEIALKSPRSRRNFEHTLANNIRSVIKEGKIWRSQGVLFLEVNDDNKNIEELSKVFGIASFSPVMSIKSYNNNLEDIINKAKEVFAEIVKGKIFSVRAKRIGSHNFTSLDVQRKVGEALYPFSRGVNLENPEVEVFIEIRNDVAYFYHKIIKGPKGLPVGVAGKTVVLFSGGIDSPVATWMMMKRGSIPVILNFNLGGSIHRKFVLEELSVLRKWSGGHKLKLFIVNGTDVLIKLSQIEKRNRVVMLKRVMYKVAERLCDKANAKSITTGESLSQVSSQTMTNLYVTEYGIKYPIFRPLIGFDKEEIVELARKIGTYQYSIKLPEYCAISTKARTSVELDEVLKDEENLNIDYEKVLENSEVIEI
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_CAMJ8
Sequence: MRRRKAPVREVLPDPIYGNKVITKFINSLMYDGKKSTATTIMYGALEAIDKKGGEKKGIDIFNDAIENIKPLLEVKSRRVGGATYQVPVEVRPARQQALAIRWIISFARKRSERTMIDKLAAELLDAANSKGASFKKKEDTYKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: HTPG_NITOC
Sequence: MTVASHKETLGFQTEVKQLLNLMIHALYSNKEIFLRELISNGADAADKLRFEALTDDALYEDDSALHIRLSYDKDKRTLTIADNGIGMGRQEVVENIGTIAKSGTRAFLESLSGDQAKDARLIGQFGVGFYSAFIVADKVVLETRRAGFGPEHGVRWESGGAGDYTIETIEKATRGTVVTLHLREGEDEFLDGWRLRHIVTRYSDHIDLPIEIKREIGDEEKSEENGEEWEQINKATALWTLPKNDIKEEEYQAFYKHVAHDFEDPLAWTHNRVEGKLEYTSLLFIPPRAPFDLWERDRTQGIKLYVQRVFIMDDTEQLMPRYLRFVRGVVDSNDLPLNISREILQNNRVIDSIRAGSVKKILGLLEDMAKHEAKKYQSFWKEFGQVMKEGVGEDSGNREQIARLLRFASTHHDTAEQTVSLADYLSRMKEGQDKIYYITADSFPAAKSSPHLEVFRKKGIEVLLLSDRVDEWLVASLPEFEGKSLQSVTKGELDLGHLEDEQEKQQQKEVEEDFQNLVERVKNNLGDKVKEVRVTHRLTDSPVCLVVEQHDMSGYLERLLKEAGQQAPHIQPILELNPAHPIIARLKGEESEENFGDWAHLLFEQALLAEGGRLEEPALFVKRLNSLLLAMAD
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCHS_DROME
Sequence: MDFKEYRQRGKEMVDYIADYLENIRERRVFPDVSPGYMRQLLPESAPIEGEPWPKIFSDVERIVMPGITHWQSPHMHAYFPALNSMPSLLGDMLADAINCLGFTWASSPACTELEIIVMNWLGKMIGLPDAFLHLSSQSQGGGVLQTTASEATLVCLLAGRTRAIQRFHERHPGYQDAEINARLVAYCSDQAHSSVEKAALIGLVRMRYIEADDDLAMRGKLLREAIEDDIKQGLVPFWVCATLGTTGSCSFDNLEEIGIVCAEHHLWLHVDAAYAGSAFICPEFRTWLRGIERADSIAFNPSKWLMVHFDATALWVRDSTAVHRTFNVEPLYLQHENSGVAVDFMHWQIPLSRRFRALKVWFVLRSYGIKGLQRHIREGVRLAQKFEALVLADHRFELPAKRHLGLVVFRIRGDNEITEKLLKRLNHRGNLHCIPSSLKGQYVIRFTITSTHTTLDDIVKDWMEIRQVASTVLEEMNITISNRVYLKETKEKNEAFGSSLLLSNSPLSPKVVNGSFAAIFDADEFLAKTYAGVRIAHQESPSMRRRVRGILMSGKQFSLDSHMDVVVQTTLDAGNGATRTSTTNSYGHTTSAAQANSERQASIQEDNEESPEETELLSLCRTSNVPSPEHAHSLSTPSRSCSSSSHSLIHSLTQSSPRSSPVNQFRPITLCAVPSQSQLSMPLAMPLPNRNVTVSVDSLLNPVTTCNVYHGKRFLEPLENLAQTSASFSSSIFRLPTPIATPTRESPEDPDWPAKTFSQLLLERYSSQSQSLGNNSSTESSSLSGGATPTPTPMSSLDELVTPLLLSFASPSQPMLSAHGIGEGQREQGSDSDATVCSTTSSMESL
What is the function of this protein?
Required in photoreceptor transmitter synthesis (PubMed:8096176).  Catlayzes the conversion of L-histidine to histamine (Probable).
What are the official names of this protein?
Histidine decarboxylase, HDC.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: PSMA1_STAAT
Sequence: MGIIAGIIKVIKSLIEQFTGK
What is the function of this protein?
Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection.
What are the official names of this protein?
Phenol-soluble modulin alpha 1 peptide.
What is the protein family that this protein belongs to?
Belongs to the phenol-soluble modulin alpha peptides family.