PharMolix/UniProtQA huggingface dataset:
Protein: HIS1_CALBD
Sequence: MITIALPKGRLAQQTVELLKRASLVDIDISEESRKLIIEDTQNSLRFLMVKPFDVPTYVEYGVADVGVVGKDVLLEMNKRVYELLDLKIGKCFVALAGPKGISEALLKKPDKTIATKFPNIAKEYFENVRGEDVKIIKLNGSVELAPILGLSDMIVDIVESGRTLKENGLEVYEKLYDISARLIANRASLKLKTQIDDIINRLERMIEE
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTU1_SCHPO
Sequence: MSNKLCQLCNERRPALVRPKTGQKICKECFYYVFETEIHNVIIENKLFVRGERVGIGASGGKDSTVLAYVMKLLNERYDYGLELYLISVDEGIRGYRDDSLDTVKRNQQQYGLPMKIVSYADLYDGWTMDNVVARIGTKNNCTYCGVFRRQALDRAALSLDIHHLVTGHNADDIAETILMNLLRGDVARLPRSTEITTQSDSSPTKRSKPFKYSYEKEIVLYAHYKKLDYFSTECTYSPEAFRGTARAMIKQLENIRPSSILDIIYSGESMQLASSVQEQLPQQTTCERCGFISSNRICKACMLLEGLNKGITGLGLGSDRKTKKLQSQIPACAE
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation.  It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated urm1 onto the uridine of tRNAs at wobble position.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  May also be involved in protein urmylation.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 1, Cytoplasmic tRNA adenylyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODPA_STAAM
Sequence: MAPKLQAQFDAVKVLNDTQSKFEMVQILDENGNVVNEDLVPDLTDEQLVELMERMVWTRILDQRSISLNRQGRLGFYAPTAGQEASQLASQYALEKEDYILPGYRDVPQIIWHGLPLTEAFLFSRGHFKGNQFPEGVNALSPQIIIGAQYIQAAGVAFALKKRGKNAVAITYTGDGGSSQGDFYEGINFAAAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDALAVYQATKEARDRAVAGEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWEKKDPLVRFRKFLENKGLWNEDKENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYEDMPQNLAEQYEIYKEKESK
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit alpha.
Protein: KTAS1_HUMAN
Sequence: MEAAGGFQVHFHPSNGDGRFIETSSAADLEVISYSSKVSVTERCFIKVCTVLF
What are the official names of this protein?
Putative uncharacterized protein KTN1-AS1, KTN1 antisense RNA 1, KTN1 antisense gene protein 1.
Protein: HAK18_ORYSJ
Sequence: METRTNEYSRKGAMWELERNLDQPMDAEAGRLRNMYREKTYPTILLLRLAFQSLGVVFGDLGTSPLYVFYNIFPHGIEDTEQVIGALSLIIYSLTLIPLVKYVFIVLRANDNGQGGTFALYSLLCRHAKINIIPNQHRTDQDLTTYSRRTYEEKSLAAKIQRWLEGHQFRKNLILILVLFGTCMAVGDGILTPAISVLSATGGIQVEEGRMRNDVVVIISVLILIGLFSMQHYGTDKVSWLFAPIVFVWFILIGILGAVNICKYDHSVLKAFNPVYVYRYFKRGKTSWTSLGGIMLSITGTEALFADLSYFPVQAIQIAFTVVVFPCLLLQYTGQAAFIAANTNQVSHAFYISLPAPILWPAFAVATAAAIVASQATISATYSIIKQALALGCFPRVKIIHTSKKYLGQIYSPDINWILMVFCIAVTAGFKNQSQIANAYGTAVIMVMLVTTFLMIPIMLLVWRSHWTLVVAFTVLSLLVEIPYFSAVVRKIDQGGWVPLVFAAGFMIIMYVWHYGTLKRYEFEMHSKVSMAWILGLGPSLGLVRVPGIGLVYTELASGVPHIFSHFITNLPAIHSTLVFVCVKYLPVYTVPPDERFLVKRIGPKNFHMFRCVARYGYKDIHKKDDDFEKMLFDSLILFVRLESMMEEYSDSDEYSTLMMSLPNNPGISNGGVTTTGTNNVMEVMSCTSTHDSIVPVNSRSDDTGSSQVMPASGQMAFQSVGDEIAFLNACRDAGVVHILGNTVIRARRDSGFVKKIVINYMYAFLRKICRENSAIFNVPHESMLNVGQVFYV
What is the function of this protein?
High-affinity potassium transporter.
What are the official names of this protein?
Potassium transporter 18, OsHAK18.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MMM1_CANAW
Sequence: MSQDLIETTATTTKIVEARELGHQIHDSLLEQLKLQQEELLQQQRDLFFQEQQLQLQQQVTQPVSNNGNTWSFTQGLVIGQVSVIFIIIVFVKFFVFADSSSHIPTKPGLDGAIGVIVKRNKNKKHSNGQFANDGENEDDTSLDSNQSKISSILEKTYYDVNNHASESLDWFNVLVAQTISQLRSEALLKDNIYHSLNNFLTNAKLPDFIDTINLTEIDIGDDFPIFSNCRIKYGEDLKRLEAKIDVDLSDTLTLGIATKLLLNQPRPLTAVLPVSLTVSIVRFSGCLTVSLINTKDIDLKNVDKTSNMNGYSKENANGDGASSSNNDEDEDDGGTALMFSFSPDYRLEFIVKSLIGSRAKLQDVPKISSLIENQLRTWFIERCVEPRFQVVRLPSLWPRTKNTREPVTKKTTTTPSTTVNGTSAATITTPGEYVNSNI
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Maintenance of mitochondrial morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the MMM1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: YHYA_BPH44
Sequence: MSRDPTYTINEHDLSFADGRFYVTFKADKSSETVRLNSSCLGNTIIKKLQVEDDNTMHDFVKPKVTTQQAFGLAQQVKELDLQLKDPKSDLWGKIKFNNKAMLVEYANKEMSSAIAQSAEQILLQVKSIDDERYSKFEQTLNGIKQTVKSESVESARTQLASMFDSRISGLDGKYSRLSQTIDSLSSRLDDGVGNYSTLSQKVSGIDLRVSNAANDVSRLSQTAQGLQSQITNANQNYSSLSQTVQGLQTTVRDNQSNATSRINQLSDLISTKVTKGDVETTIAQSYDKIAFAIRDKLPASKMTGSEIISAINLDRSGVKITGKNITLDGNSYISNAVIKDAHIANMDAGKINTGYLNASRIAAEAITGDKIKMDYAFFNKLTANEGYFRTLFAKNIFTTSVQAVTTSASKITGGVLSATNGASRWDLNSANIDFNRDATINFNSKNNALVRKSGTNTAFVHFSNATPKGYRGSALYASIGITSSGDGIDSASSGRFCGVRFFRYAEGLQHTAKVDQAEIYGDDIVFSDDFNIDRGFKMRPSLMPKMVDLNKMYQAILALGRCWLHANNTAWSWNFDTRSAIIAEYNAHINNL
What are the official names of this protein?
Uncharacterized 65 kDa protein in hyaluronidase region.
Protein: NIFW_AZOVD
Sequence: MTVQPFSPDSDLTLDEAMDELVSAEDFLEFFGVPFDQDVVHVNRLHIMQRYHDYLSKAGDLDEHDDQARYAVFQKLLARAYLDFVESDALTEKVFKVFRMHEPQKTFVSIDQLLS
What is the function of this protein?
May protect the nitrogenase Fe-Mo protein from oxidative damage.
What are the official names of this protein?
Nitrogenase-stabilizing/protective protein NifW.
What is the protein family that this protein belongs to?
Belongs to the NifW family.
Protein: Y160_ACICJ
Sequence: MADGAAEIRGRLRRVVLDEDIGGALSPMQEADRNQAIADLAADNRFALGTHPDAVTILHLSVQDGRLVFDVRDEADETLQTLVLAPGPFRSMIRDYQMLLDSYATAVAEGREARIQAIDMGRRGLHNEGAELVMARLDGKVLLDFDTARRLFTLICALHRRA
What are the official names of this protein?
UPF0262 protein Acry_0160.
What is the protein family that this protein belongs to?
Belongs to the UPF0262 family.
Protein: Y680_HAEIN
Sequence: MFKGILVSLLASFLFGYMYYFSTLLKPLSGTDIFGYRMIFTFPFVLLSVTLFKQKAALIERLKRIQKRPHLALSYLLCGLLMGFQMWLFLWAPNNGSSLSVSFGYLLLPIVMVAAGRVFFKERISTFKFIAVIIATLGVISNIVLKGGLSWEAIVICLGYTAYFSIRKALKNTDLASFCLEMLSLMPVSIYFALQTDFATVQQTNPFIWGXLVLLGLISGTALIAYVIASNMLPMNLLGLLGYVETIMMLCVSFLIGEQIDSESYPLFICLVIAMILVMVDGVYKHTQKEVYKCHLKK
What are the official names of this protein?
Uncharacterized transporter HI_0680.
What is the protein family that this protein belongs to?
Belongs to the EamA transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SWT13_ORYSJ
Sequence: MAGLSLQHPWAFAFGLLGNLISFTTYLAPIPTFYRIYKSKSTEGFQSVPYVVALFSAMLWIFYALIKSNEALLITINAAGCVIETIYIVMYLAYAPKKAKVFTTKILLLLNVGVFGVILLLTLLLSHGEQRVVSLGWVCVAFSVSVFVAPLSIIKRVIQSRSVEYMPFSLSLTLTLSAVVWFLYGLLIKDKYVALPNILGFTFGVVQMGLYVFYMNATPVAGEGKEGKGKLAAAEELPVVVNVGKLAAATPDRSTGAVHVHPVPRSCAAEAAAAEPEVLVDIPPPPPPRAVEVAAV
What is the function of this protein?
Confers blight susceptibility (PubMed:25988582).  Confers TAL effector-mediated susceptibility to Xanthomonas oryzae pv.  oryzae (PubMed:23879865).
What are the official names of this protein?
Bidirectional sugar transporter SWEET13, OsSWEET13.
What is the protein family that this protein belongs to?
Belongs to the SWEET sugar transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FOLD_BRUC2
Sequence: MAQLIDGKKLAEDVVSTVKTETEKLVAATGVVPGIAVVIVGEDPASQVYVASKSRKAKECGFHSVQHDLPETASEQELLNLIEGLNNDPAIHGILVQLPLPGHIDSGRVIQTIAPEKDVDGFHFINVGKLGTGEVETAFVPCTPAGAMIMIERVHGRDLSGLNAVVIGRSNIVGKPMFNLLLAANATVTVAHSRTKDLPAIARNADILVAAVGRPQMVKGDWVKPGATVIDVGINRIPAPERGEGKTRLVGDVDFAEAEKVAGAITPVPGGVGPMTIAMLMANTLTAACRSAGMKKPVF
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: MVP_CYLCV
Sequence: MDVLDYLDMSESSEKFHVSVLSEKDKFKIESADITLKEGDDFKRISTIRNIFDRKNVIFYGKYLSESFVKLETASGKFELPIVNIDHIYDQISKIRNQEKRKTLSCIHISTIQIVLKSTFLKGLDYPISLAITDERINNPKEKIIGIVHGNLATVTLKFSVHLGFAIPLTEEDLSRSISLTYKAYRNDLMNDQKQGFSITYAVSYALANSHHSIQFANKDRIYLDEIFKQVSFTEKPRPISPIKPNGLKFLKKKPSNLEDLIGVPRNHLSLQPPPLRVARKDSEESSSTSVPEIENLTKQVKDISSYLKDRL
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Acts by forming tubules structures that increase the size exclusion limit (SEL) of plasmodesmata, thereby allowing viral ribonucleocapsids to spread directly to neighboring cells (By similarity).
What are the official names of this protein?
Putative movement protein, Mov, Cell-to-cell transport protein.
What is the protein family that this protein belongs to?
Belongs to the caulimoviridae movement protein family.
What are the subcellular locations of this protein?
Host cell junction, host plasmodesma. Note=Assembles in tubules that are embedded within modified plasmodesmata.
Protein: RUVC_AZOVD
Sequence: MTLILGIDPGSRITGFGVVRDGGRGCEYIASGCIRTGSGSLPERLQAVYRGVTEIIRSHGPVTMGIEQVFMARNADSALKLGQARGAAIVAAAEAGLEIAEYTATQVKQAIVGSGGADKRQVQMMVMHLLRLVQKPQIDASDALAIALCHAHHRQSLIPHGLDGARRRGGRLRL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: AZUR_ACHDE
Sequence: MLAKATLAIVLSAASLPVLAAQCEATIESNDAMQYNLKEMVVDKSCKQFTVHLKHVGKMAKVAMGHNWVLTKEADKQGVATDGMNAGLAQDYVKAGDTRVIAHTKVIGGGESDSVTFDVSKLTPGEAYAYFCSFPGHWAMMKGTLKLSN
What is the function of this protein?
Transfers electrons from cytochrome c551 to cytochrome oxidase.
What are the official names of this protein?
Azurin.
What are the subcellular locations of this protein?
Periplasm.
Protein: NU3C_PAUCH
Sequence: MFVLSGYDAFLGFLLIATAVPVLALLTNKILAPKSRNGERELTYESGMEPVGGAWIQFNIRYYMFALVFVIFDVETVFLYPWAVAFHRLGLLAFIEALIFIAILVIALAYAWRKGALEWS
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, organellar chromatophore, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Plastid, organellar chromatophore thylakoid membrane; Multi-pass membrane protein.
Protein: NUOA_NITEU
Sequence: MLNTMLGNYFPILLFILVGLAIGVLSMLAGWLLAPNKPDAEKLSPYECGFGAFEDARMKFDVRYYLIAILFILFDLEIAFLFPWAVVLKEIGWFGFVAMLVFLGLLVVGFIYEWVKGALEWD
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: REG3B_MOUSE
Sequence: MLPPTACSVMSWMLLSCLMLLSQVQGEDSLKNIPSARISCPKGSQAYGSYCYALFQIPQTWFDAELACQKRPGGHLVSVLNSAEASFLSSMVKRTGNSYQYTWIGLHDPTLGAEPNGGGWEWSNNDVMNYFNWERNPSTALDRAFCGSLSRASGFLKWRDMTCEVKLPYVCKFTG
What is the function of this protein?
Acts as a hormone in response to different stimuli.  Secreted by different cell types to activate its receptor EXTL3 and induce cell specific signaling pathways (PubMed:34099862).  In pancreas, is able stimulate cell proliferation (PubMed:34099862).
What are the official names of this protein?
Regenerating islet-derived protein 3-beta, REG-3-beta, Pancreatitis-associated protein 1, Regenerating islet-derived protein III-beta, Reg III-beta.
What are the subcellular locations of this protein?
Secreted. Note=Found in the apical region of pancreatic acinar cells.
Protein: END3_BACSU
Sequence: MLNLKQIEFCLDKIGDMFPHAECELVHSNPFELVVAVALSAQCTDALVNRVTKTLFQKYKRPEDYLAVPLEELQQDIKSIGLYRNKAKNIQKLSKMIIEDYGGEVPRDRDELVKLPGVGRKTANVVVSVAFGVPAIAVDTHVERVSKRLGICRWKDSVLEVEKTLMRKVPKEDWSVTHHRLIFFGRYHCKAQSPRCAECPLLSLCREGQKRDKKGLVKR
What is the function of this protein?
DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity.  The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site.  The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
What are the official names of this protein?
Endonuclease III, DNA-(apurinic or apyrimidinic site) lyase.
What is the protein family that this protein belongs to?
Belongs to the Nth/MutY family.
Protein: MURC_FRATM
Sequence: MNKKILFLGVGGIGVSALAIAAKRLGAHVAGYDSVANKLTAKLEALGIVIFTSPNGVDVANFDIVVYSSAILSSHPLLSQARSLGIQCLQRAMFLSVLMKDFSYSIAITGTHGKTTTSSVLATLLCQLDKYSSFIVGGVVKYADSNIQVNGTDKLVIEADESDASFLFLSPQVVIITNIDLDHMATYNNSYQTLLENFTDFVSKESVKSIYLCVDDQGCRDLLAKYNQSDKNVTSYGFSIDADVQIYDYHIIDEITHFKIRYKGDDLSFKLQLPGRYNVQNATACIIACLDLGFKYEDIRNALIKVTGVARRFDLYTKVISGHQVTVIDDYGHHPVEVANSISAVRDRYPNKKIIHVFQPHRYTRNRDLIKDWPKALSLADQLILLPTYSADEQIIKGAESQDIVKGLSGYLLADGFDHAIYFLEKLANENTVILIQGAGDVTNLVEILSE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRLA_PENRW
Sequence: MRSHGQQISDRLTVEVDCHSLGPSECPSMTSSFSPLDSPTPTPTSLYSQGSMASPGWPEPSHYHHGLPMERRTSATPLRSAFRMADLTSGEGMMNMPCGNMDRQEQMPLPDYLPGYDENVDQLWIPQDMPKTYQEPQFPYQASMPQYNQMARNYYHRPQQAGYLPESASNPCLSRPIFTQSTERMPNSASMSNMLGWMPSHESLVPQTITPAQVQPFPSGPVTPPSSSYSDFPANIPTFKTHTPSTPHRSVSMGTPSGSDTPVSRMSGHNDYQEDFQLSPVYREGMMQRHRQPSRKSSKKQLLRSNLSLENLPSIIKQVQFKCKEPGCKGRFKRQEHLKRHMKSHSKEKPHVCWIPGCHRAFSRSDNLNAHYTKTHSKRGGRNRYVATLDETSQDFDPDFRGQLTPDGRPIYGSKLEDTMPDCGELSVDGWDD
What is the function of this protein?
BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation (By similarity).  They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (By similarity).  Binds promoters of target genes at brlA response elements (BREs) containing the conserved sequence 5'-(C/A)(A/G)AGGG(G/A)-3' (By similarity).  Is not required for penicillin V production (PubMed:21148688).
What are the official names of this protein?
C2H2 type master regulator of conidiophore development brlA.
What are the subcellular locations of this protein?
Nucleus.
Protein: YIA4_MYCTU
Sequence: MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASAFFAAELDRPAR
What are the official names of this protein?
Insertion element IS6110 uncharacterized 12.0 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the transposase 8 family.
Protein: HIS81_GLUOX
Sequence: MIPSHTAPSPFFPWSHRMNTAPECRTPPLSLARAEVRQLPVYNAGLSEDAVRAKYGIPRITKLGSNENPYGPSPAALEHWTEIASSLFRYPDASAEGLREELSRQTGIDTDRIVIGNGSEQIIRMICEAFLSPGDRLVTVLPSFGLHLIWPQMMGARAEAIPMTADARFDLPQLHQAVTSDPLKVLMFSNPSNPVGCLMTGDAMQSLIDACPADTLIVIDEAYWEYARSSPDYADSLTILKNQSRPWMVLRTFSKAYGLAGLRVGYALTSDPGLTAVMTRVRDPFNSNSAALEMARLSLLDQEHMHKTVGATLAEGKALKAALEERGYFVAQSFANFLFFNARESASALAERLLEQGVIVKPWKEKGYETWIRVSIARPEDSQAFLAALDRVRQPSHSSAA
What are the official names of this protein?
Histidinol-phosphate aminotransferase 1, Imidazole acetol-phosphate transaminase 1.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: APT_CLOB1
Sequence: MNLKEHIRVIENFPKEGISFKDVTTILQDGKVLNYTIDKLAENLKDKKIDKIVGPEARGFLFGTPLAYKLGVGFVPVRKKGKLPYETISCKYDLEYGQDELQIHKDSIKKGDKVAIVDDLLATGGTIASVVKLVEELGGEVVNVSFVIELTDLKGKDKLEGYDINSLVQYNI
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SP20H_CHICK
Sequence: MQQALEQALDRAEYIIESARQRPPKRKYLSSGRKSVFQKLYDLYIEECEKEPEIKKLRRNVNLLEKLVMQETLSCLVVNLYPGNEGYSLMLRGKNGSDSETIRLPYEEGELLEYLDAEELPPILVDLLEKSQVNIFHCGCVIAEIRDYRQSGNMKSPTYQSKHILLRPTMQALICDVHSITSDNHKWTQEDKLLLESQLILATAEPLCLDPSIAVTCTTNRLLYNKQKMNTRPMKRCFKRYSKSSLNRQQEVAHYSTPPQLRLVDYLQKRKGKKGAQQYDLKISKAGNCVDMWKQNPCYLTAPSEVDVEKYAKVESSIKPDDSQPTVWPAHEVKDDYVFECEVGNQLQKTKLTIFQSLGNPLYYGKIQTLKGDDESDSLLVPPQFLIGSKTDAERVVNQYHELVKSEAKCPVKMFHNSGGSINLSHLSPGKEMEPESISGSVQSSVLGKGVKHRPPPIKLPSSSGSSSSGNIFSPQQSSGHLKSPTPPPPPPTSKPPGLSRKQSMDLNQVSMLSPAAMSPASSSQRTTSTQVMANPAGLNFINVVGSVCGAQTLMSGSNPMLGCNTGAIAPAGINLSGILPSGGLVPSALPATMQSASQAGSPFGLKNASNLRPLNLLQGSDQGPSNQDQALSAQQAAVINLTGVGNFMQPQATAVAILAASNGYGSSSSTSSSSATSAAFRQPLKK
What is the function of this protein?
Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation.
What are the official names of this protein?
Transcription factor SPT20 homolog.
What is the protein family that this protein belongs to?
Belongs to the SPT20 family.
Protein: RS21_STRMU
Sequence: MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVKRKRKSEAARKRKKF
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: PI42C_XENTR
Sequence: MSSSGAMPAVSSASSSAAVGILSATTAKTKTKKKHFVQQKVKVFRASDPLISVFMWGVNHSVNELIQVPVPVMLLPDDFKANSKIKVTNHLFNRENLPSHFKFKDYCPQVFRNLRERFGIDDQDFQASLTRSSPYCESEGHDGRFLLSYDKTLVIKEISSEDVADMHNILSHYHQHIVKCHGNTLLPQFLGMYRLSVDNEDSYIMVMRNMFSHRLTVHRKYDLKGSLVSREASDKEKIKELPTLKDMDFLNKSQKVYVDEEQKKNFMEKLKRDVDFLVQLKLMDYSLLLGIHEVFRAEQEEEEDLEEDHTENESSPHMNVGSYGTSPEGIAGYLNSHKPLGPGEFEPIIDVYAIKSSDNAPQKEVYFMGLIDILTHYDAKKKAAHAAKTVKHGAGAEISTVHPDQYGKRFLEFVTNIFA
What is the function of this protein?
Phosphatidylinositol 5-phosphate 4-kinase with low enzymatic activity.  May be a GTP sensor, has higher GTP-dependent kinase activity than ATP-dependent kinase activity.
What are the official names of this protein?
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma, Phosphatidylinositol 5-phosphate 4-kinase type II gamma, PI(5)P 4-kinase type II gamma, PIP4KII-gamma.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Cytoplasm.
Protein: GPPA_SALPA
Sequence: MNSTSLYAAIDLGSNSFHMLVVREAAGSIQTLTRIKRKVRLAAGLNNDNHLSAEAMERGWQCLRLFAERLQDIPQPQIRVVATATLRLAVNAGEFIAKAQTILGCPVQVISGEEEARLIYQGAAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSLSMGCVTWLERYFSDRNLAQENFDDAEKAARDVLRPVADELRFHGWKVCVGASGTVQALQEIMMAQGMDERITLAKLQQLKQRAIQCGRLEELEIEGLTLERALVFPSGLAILIAIFTELNIQSMTLAGGALREGLVYGMLHLAVDQDIRSRTLRNIQRRFIVDTDQANRVAKLADNFLKQVENAWHIEPISRELLLSACQLHEIGLSVDFKQAPYHAAYLVRHLDLPGYTPAQKKLLATLLLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAILFAGRRRDDLVPEITLQALNENLTLTLPGDWLAHHPLGKELIDQESQWQSYVHWPLDVR
What is the function of this protein?
Catalyzes the conversion of pppGpp to ppGpp.  Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
What are the official names of this protein?
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, Guanosine pentaphosphate phosphohydrolase, pppGpp-5'-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family. GppA subfamily.
Protein: Y1780_PASMU
Sequence: MRKYSVITYREDETVEGQPFIIATGKTYQAAAQIAREAMDNDPLVYGSTLRVERSPYEITVFDKQGEIAFVGEYPTYAQACDVSDYLKTTGLYSEIRISHPDGLGGEQ
What are the official names of this protein?
Uncharacterized protein PM1780.
Protein: RGS21_HUMAN
Sequence: MPVKCCFYRSPTAETMTWSENMDTLLANQAGLDAFRIFLKSEFSEENVEFWLACEDFKKTKNADKIASKAKMIYSEFIEADAPKEINIDFGTRDLISKNIAEPTLKCFDEAQKLIYCLMAKDSFPRFLKSEIYKKLVNSQQVPNHKKWLPFL
What is the function of this protein?
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.
What are the official names of this protein?
Regulator of G-protein signaling 21, RGS21.