PharMolix/UniProtQA huggingface dataset:
Protein: KTHY_AYWBP
Sequence: MFISFEGCEGTGKTTHSSYLFEKLSKKYSCVLTKEPGGGLFNEVIRNILLHSYNKQIDFHTEALLFAADRAEHLSKLIIPALQQNKIVICDRYLDSTIAYQVYARGLSKDFVLNINNLALNYMPNITFYLDLDPKIGIQRVKQFRPKEINSFDLQKLSFHKKVRKGYLDLYQKDQQKRIFLIDASKSLEKIYNIIEQKLKEVFQIDL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: RLMH_NEIMF
Sequence: MNITVLAVGTKMPRWVDEAVAEYAKRFGRDVAYVLKEIKPEKRGAGVNAAQGMAAEEKRILEAIPQGAFLVVLDERGKAPTSVELAEHLKTWQQNGEHVCFVIGGADGMTDRLKQQARMMMRLSSLTLPHGMVRVLLTEQLYRAASILHNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_STRPB
Sequence: MSFNHKTIEELHDLLVAKEISATELTQKTLEDIKSREEAVGSFITVSEEAALKQAAAIDAKGIDADNLMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFDATSVANAYAKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHTKVPGGSSGGSATAVASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGTVSRYGLIAFGSSLDQIGPFAPTVKENAQLLNVIASSDVKDATSAPVRIADYTSKIGRDIKGMKIAFPKEYLGEGIDPKIKETVLAAAKQFEALGATVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRADDAKNLDEIYVNTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIEDFDKVFADYDLILGPTTPAVAFGLDTLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFVDGLPVGLQLIGPKYAEETIYQAAAAFEAVTDYHKQQPIIFGGDK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: CPPS2_MAIZE
Sequence: MVLSSSCTTVPHLSSLAVVQLGPWSSRIKKKTDAVAVPAAAGRWRARARAQDTSESAAVAKGSSLTPIVRTDAESRRTRWPTDDDDAEPLVDEIRAMLTSMSDGDISVSAYDTAWVGLVPRLDGGEGPQFPAAVRWIRNNQLPDGSWGDAALFSAYDRLINTLACVVTLTRWSLEPEMRGRGLSFLGRNMWKLATEDEESMPIGFELAFPSLIELAKSLGVHDFPYDHQALQAIYSSREIKVKRIPKEVMHTVPTSILHSLEGMPGLDWARLLKLQSSDGSFLFSPAATAYALMNTGDDRCFSYIDRTVKKFNGGVPNVYPVDLFEHIWAVDRLERLGISRYFQKEIEQCMDYVNRHWTEDGICWARNSDVKEVDDTAMAFRLLRLHGYSVSPDVFKNFEKDGEFFAFVGQSNQAVTGMYNLNRASQISFPGEDVLHRAGPFSYEFLRRKQAEGALRDKWIISKDLPGEVVYTLDFPWYGNLPRVEARDYLEQYGGGDDVWIGKTLYRMPLVNNDVYLELARMDFNHCQALHQLEWQGLKKWYTENRLMDFGVAQEDALRAYFLAAASVYEPCRAAERLAWARAAILANAVSTHLRNSPSFRERLEHSLRCRPSEETDGSWFNSSSGSDAVLVKAVLRLTDSLAREAQPIHGGDPEDIHKLLRSAWAEWVREKADAADSVCNGSSAVEQEGSRMVHDKQTCLLLARMIEISAGRAAGEAASEDGDRRIIQLTGSICDSLKQKMLVSQDPEKNEEMMSHVDDELKLRIREFVQYLLRLGEKKTGSSETRQTFLSIVKSCYYAAHCPPHVVDRHISRVIFEPVSAAK
What is the function of this protein?
Involved in gibberellin biosynthesis (PubMed:16307364).  Catalyzes the conversion of geranylgeranyl diphosphate to the gibberellin precursor ent-copalyl diphosphate (ent-CPP) (PubMed:16307364).  Involved in the production of antifungal dolabralexin phytoalexins in response to biotic and abiotic stresses (PubMed:29475898).  In response to fungal infection and in associtation with KSL4, is involved in the production dolabradiene, a type of antifungal phytoalexin (PubMed:29475898).
What are the official names of this protein?
Ent-copalyl diphosphate synthase 2, chloroplastic, Ent-CPP synthase 2, Ent-CPS 2, Protein ANTHER EAR 2, ZmAN2.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsc subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NIKR_DESVV
Sequence: MGRTIRFGVSLDSELLDKFDVLCDERCYQTRSEAIRDLIRNTLVQQEWEDTDREIAGTLTLVYDHHKSDLAQRLTEIQHDVHDIIITSLHVHLDHYNCLEVLVLKGPGQQVRNLAQRLISTKGVKHGKLSLTTTGQDLT
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: EPS1_YEAST
Sequence: MKMNLKRLVVTFFSCITFLLKFTIAAAEPPEGFPEPLNPTNFKEELSKGLHIIDFYSPYCPHCKHLAPVWMETWEEFKEESKTLNITFSQVNCIESADLCGDENIEYFPEIRLYNPSGYIKSFTETPRTKESLIAFARRESMDPNNLDTDLDSAKSESQYLEGFDFLELIAGKATRPHLVSFWPTKDMKNSDDSLEFKNCDKCHEFQRTWKIISRQLAVDDINTGHVNCESNPTICEELGFGDLVKITNHRADREPKVALVLPNKTSNNLFDYPNGYSAKSDGYVDFARRTFTNSKFPNITEGELEKKANRDIDFLQERGRVTNNDIHLVFSYDPETVVIEDFDILEYLIEPLSKIPNIYLHQIDKNLINLSRNLFGRMYEKINYDASQTQKVFNKEYFTMNTVTQLPTFFMFKDGDPISYVFPGYSTTEMRNIDAIMDWVKKYSNPLVTEVDSSNLKKLISFQTKSYSDLAIQLISSTDHKHIKGSNKLIKNLLLASWEYEHIRMENNFEEINERRARKADGIKKIKEKKAPANKIVDKMREEIPHMDQKKLLLGYLDISKEKNFFRKYGITGEYKIGDVIIIDKSNNYYYNKDNFGNSLTSNNPQLLREAFVSLNIPSKALYSSKLKGRLINSPFHNVLSFLDIIHGNGMPGYLIVIVLFIAILKGPSIYRRYKVRKHYRAKRNAVGILGNMEKKKNQD
What is the function of this protein?
Acts as a membrane-bound chaperone in endoplasmic reticulum quality control.  Probably facilitates presentation of substrate to membrane-bound components of the degradation machinery.
What are the official names of this protein?
ER-retained PMA1-suppressing protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: VP55_LYCMC
Sequence: MNFLCILFVVSLISSLSKCTTSSMKRELDLGMSRGHSGSQVGKALLGIQSANRTDGPGRKRRSFDLYALVNAK
What is the function of this protein?
Regulates fluid secretion.
What are the official names of this protein?
Venom protein 55.1.
What is the protein family that this protein belongs to?
Belongs to the diuretic hormone class 2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GSA_TERTT
Sequence: MSNFSEVFARAQKTIPGGVNSPVRAFKAVGGEPVFIDHAKGAYVYDIHGKRYVDYVLSWGPMLLGHGDDDVLDAVRAKLDKGLSFGAPTEIETELAEKICNIMPGMDKVRFVNSGTEATMSAIRLARGYTGRDKIVKFEGCYHGHSDSLLIKAGSGALTLGVPSSPGVPACLAEHTITLTYNNIEQVRQLFRDRGNEIACIIVEPVAGNMNCIPPEPGFLQALREVCTQADALLIFDEVMTGFRLGLSGAQGYYQVQPDITTLGKVIGGGMPVGAFGGSERIMDFIAPVGPVYQAGTLSGNPVAMAAGLKTLEKISAEGFYQPIFDKTAALCRNLESAAKEAGIGFTTNYVGSMWGGFFTEEEKISNYQQVMACNTERFNRFFHGMLDEGVYLAPASYEAGFMSVSHSDEDIDFTVNAARKVFANIK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_RHOPT
Sequence: MTIQKNWQELIRPNKLQVTPGSDATRFATLVAEPLERGFGQTLGNALRRVLLSSLQGAAVQSVHIDGVLHEFSSIAGVREDVTDIVLNIKDISLKMQGEGPKRMVVKKQGPGAVTAGDIQTVGDIVVLNPDLQLCTLDDGAEIRMEFTVNTGKGYVAAERNRPEDAPIGLIPVDSLYSPVRKVSYKVENTREGQILDYDKLTMTVETNGAISPEDAVAFAARILQDQLNVFVNFEEPRKEVTQEIIPDLAFNPAFLKKVDELELSVRSANCLKNDNIVYIGDLVQKSEAEMLRTPNFGRKSLNEIKEVLAQMGLHLGMEVPGWPPENIDELAKRFEDHY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: ILVD_XANCB
Sequence: MPEYRSKTSTHGRNMAGARALWRATGMKDGDFHKPIIAIANSFTQFVPGHVHLKDLGQLVAREIERVGGVAKEFDTIAVDDGIAMGHDGMLYSLPSREIIADSVEYMVNAHCADALVCISNCDKITPGMLMAALRLNIPTVFVSGGPMEAGKTKLADHNLDLIDAMVIAADDSASDEKVAEFERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGTVVATHADREQLFLRAGRVAVELCHRWYGGEDPTALPRGIATFEAFENAMTLDIAMGGSTNTILHLLAAAQEGEVPFGMRDIDRLSKRVPQLCKVAPNTPKYHIEDVHRAGGIMSILGELARGGLLHTNAATVHTRTLADAIAQWDVTQVDDDKVHTFYKAGPAGIPTQIAFSQATRWDTLDTDRSEGCIRDVAHAFSQEGGLAVLYGNIARDGCVVKTAGVDESIHVFEGNARVYESQDSAVKGILADEVKAGDVVVIRYEGPKGGPGMQEMLYPTSYLKSKGLGKHCALLTDGRFSGGTSGLSIGHASPEAAAGGAIGLVRNGDKILIDIPKRSIDLLVSDEELAARRTEQDAKGWKPVEVRPRKVTTALKAYALLATSADKGAVRDKAMLDG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RL36_CHLFF
Sequence: MKVSSSIKADPSKGDKLVRRKGRLYVINKKDPNRKQRQAGPARKK
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: NU1C_DRIGR
Sequence: MIIDTTEVQAINSFSRSESLKEGYGLIGMLVPIFTPVSGITIGVLVIVWLEREISAGIQQRIGPEYAGPLGILQALADGTKLLFKEDLLPSRGDIRLFSIGPSIAVISILLSYSVIPFGYRLVLADLSIGVFLWIAISSIAPIGLLMSGYGSNNKYSFSGGLRAAAQSISYEIPLTPCVLSISLLSNSSSTIDIVEAQSKYGFWGWNLWRQPIGFIVFIISSLAECERLPFDLPEAEEELVAGYQTEYSGIKFGLFYVASYLNLLVSSLFVTVLYLGGWNLSIPYIFIPELFGINKTGGVFGTTIGILITLAKAYLFLFIPITTRWTLPRMRMDQLLNLGWKFLLPISLGNLLLTTSSQLLSL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic, NAD(P)H dehydrogenase subunit 1, NDH subunit 1, NADH-plastoquinone oxidoreductase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: FABZ_VIBA3
Sequence: MTTEQTTMNITEIQELLPHRYPFLMVDRVTSFEKEKTLTAIKNVSVNEPQFTGHFPQLPVFPGVLILEAMAQATGLLAFKSFGAPSGNELYYFASVDKAKFRKPVVPGDQLVIEVEFLKERRGIASFNGVAKVDGVVVCSAELKCARREF
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLRA3_MOUSE
Sequence: MSEPEVTYSTVRLHKSSGLQKLVRHEETQGPREVGNRKCSAPWQLIVKALGILCFLLLVTVAVLAVKIFQYNQHKQEINETLNHHHNCSNMQRAFNLKEEMLTNKSIDCRPSNETLEYIKREQDRWDSKTKTVLDSSRDTGRGVKYWFCYSTKCYYFIMNKTTWSGCKANCQHYSVPILKIEDEDELKFLQRHVIPENYWIGLSYDKKKKEWAWIDNGPSKLDMKIRKMNFKSRGCVFLSKARIEDIDCNIPYYCICGKKLDKFPD
What is the function of this protein?
Receptor on natural killer (NK) cells for class I MHC.
What are the official names of this protein?
Killer cell lectin-like receptor 3, 5E6, Lymphocyte antigen 49c, Ly-49c, Nk2.1, T-cell surface glycoprotein Ly-49C.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: LGT_COXBN
Sequence: MLYYPHIDPVAFRLGPLKVHWYGLMYLVGFAMAWGLALYRARDPKRHWTAQQVGDLIFYGALGLIIGGRLGYMLFYDFSNFIANPLTLFQVWRGGMSFHGGLIGVIVTTWIFSRRTHKRWMDVTDFVVPLVPLGLAAGRIGNFINGELWGRVTTVPWGMVFPNAGPLPRHPSQLYEFLLEGALLFIVIWWFSAKLRPRFAVSSLFLLCYGLFRFTAEFFRQPDPQLGFVAFGWLTRGQELSLPMIIIGGFALWWAYRHKER
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GPN3_USTMA
Sequence: MGRYAVLVSGPAGSGKSTFCSALIAHAQSLGRNVHLFNLDPAAERFEYQPSIDIKELISLEDVMEEMNLGPNGGLIYCFEYLLDNLDWLDDELGQFNDDYIIIDCPGQIELYTHFPIMSRLVNILSSQYHFRICATYLLESQFIDDKTKYFAGVLSAMSAMINLEVPHINLLSKMDLVEKGEIGSEAKRGRKREMERYLDPDPLLLMDEVNSRTNPKFHSLNQALVQLIDDFSMVSFMPLDSTDEDSVGTILSHIDNAVQYGEDEEPKEPKDMDEGDFTAQ
What is the function of this protein?
Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII).  May act at an RNAP assembly step prior to nuclear import.
What are the official names of this protein?
GPN-loop GTPase 3.
What is the protein family that this protein belongs to?
Belongs to the GPN-loop GTPase family.
Protein: Y310_HAEIN
Sequence: MKKITLFFTALLCLFSTSVLAESNSIPKQCEQLFKETENLIAQAEKQPGTHIQVNKIKSKLNQSKQQILQMELATQLKSCEVGLAKLSNLKSYSE
What are the official names of this protein?
Uncharacterized protein HI_0310.
Protein: KGUA_ACIAD
Sequence: MSGLLFVVSAASGTGKTSLVKALLERVTNLHVSVSHTTRGQRPGELDGVHYHFTTKENFLSQVEDNGFIEYAEVFGNYYGTSQATVKQQLAKGHDVLLEIDWQGAQQVRRIFPESKQIFILPPSQFDLRQRLSNRGTDAVDVIEHRLSCAVEDMQQYVNFDYIIINDDFNKALHDLESVITANRLMLAQQVQRHHKLIEQLITPNSE
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU1_METFK
Sequence: MAKGKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLTKKFGGEAKDYSQIDNAPEEKARGITINTSHVEYETETRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPYIIVFLNKADMVDDAELLELVEMEVRELLSKYDFPGDDTPIIKGSAKLALEGDQSDIGEPAIFRLAEALDTYIPTPERAVDGTFLMPVEDVFSISGRGTVVTGRVERGIVKVGDEIEIVGLKPTIKTTCTGVEMFRKLLDQGQAGDNVGVLLRGTKREEVERGQVLAKVGSIKPHTKFTAEIYVLGKDEGGRHTPFFNGYRPQFYFRTTDVTGAVELPAGTEMVMPGDNVSISVSLIAPIAMEEGLRFAIREGGRTVGAGVVAKIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu 1, EF-Tu 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NP1L2_MOUSE
Sequence: MAESVDHKELSESNQEELGSQVMAEGPGESQDRSEGVSIEPGDGGQHGEETVAAGVGEEGKGEEAAAGSGEDAGKCGGTDEDSDSDRPKGLIGYLLDTDFVESLPVKVKCRVLALKKLQTRAAHLESKFLREFHDIERKFAEMYQPLLEKRRQIINAVYEPTEEECEYKSDCEDYFEEEMDEEEETNGNEDGMVHEYVDEDDGYEDCYYDYDDEEEEEEEDDSAGATGGEEVNEEDPKGIPDFWLTVLKNVEALTPMIKKYDEPILKLLTDIKVKLSDPGEPLSFTLEFHFKPNEYFKNELLTKTYVLKSKLACYDPHPYRGTAIEYATGCDIDWNEGKNVTLRTIKKKQRHRVWGTVRTVTEDFPKDSFFNFFSPHGISLNGGDENDDFLLGHNLRTYIIPRSVLFFSGDALESQQEGVVREVNDEIYDKIIYDDWMAAIEEVKACCKNLEALVEDIDR
What is the function of this protein?
Acidic protein which may be involved in interactions with other proteins or DNA.
What are the official names of this protein?
Nucleosome assembly protein 1-like 2, Brain-specific protein, X-linked.
What is the protein family that this protein belongs to?
Belongs to the nucleosome assembly protein (NAP) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNMA_DELAS
Sequence: MTKHRVVVGLSGGVDSAVTAHLLKQQGHEVVGIFMKNWEDDDDSEYCSSNVDFVDAAAVADVVGIEIEHVNFASEYKDRVFAEFLREYQAGRTPNPDVLCNAEIKFKAFLDHAMRLGAEKIATGHYARVRQNPDTQLFELLKGLDPAKDQSYFLHRLNQAQLSRSMFPVGELKKTEVRRIAEEIGLPNAKKKDSTGICFIGERPFRDFLNRYISKEPGNILDDRNRKLGKHVGLSFYTLGQRSGLGIGGVKEKGAPRGGGDHDPWFVARKELDTNTLRVVQGHDHPWLLSQSLLADQVSWVAGHAPAEGKAYGSKTRYRQPDSPALISGATPEGFRLDFPEPQWAVTPGQSAVLYDGDVCLGGGIIAAVDPH
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_RHORT
Sequence: MTKTAAVILAAGQGTRMKSALPKVLHPLAGRPMVAHLIHALGAVAPSRTVVVIGPGMESVADRVAPLPTVLQAERLGTAHAVAQAGEALAGFDGTVLILYGDTPLITPETLTRMVEARLAAEDPAVVVLGFRPADPLQYGRLITSPAGLEAIVEYKDATAEQRAIGLCNSGVMAVDGRVLFALLAAVGNDNAKGEYYLTDIVALARGMGRACAVVEGAAEELLGVNSRSELAAAEAVIQGRLREKAMEGGATLTAPETVFFSADTRLGRDVSIGPFVTFGPGVEIGDGVEIKGFCHIEGARVAAKATLGPYARLRPGATIAEGAHVGNFVEIKNSAVEQGAKVNHLTYIGDARVGARANIGAGTITCNYDGFGKYHTDIGEGAFIGSNTALVAPVSIGAGAIIGAGSTIARDVEADALALTRGPHEVRPGWAAKFRAHMRRLTGKN
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTCA_SHEB8
Sequence: MSEELSKKHTTRLNKLQKRLRREVGSAIADYNMIEDGDKIMCCLSGGKDSYAMLDILMNLQQRAPIQFEIIAVNLDQKQPGFPEHVLPAYLDKLNVPYHILEKDTYSIVKDKIPEGKTTCSLCSRLRRGTLYGFAQRIGATKIALGHHRDDIIETLFLNMFFGGKMKAMPPKLLSDDGANVVIRPLAYCREKDLEEYANLREFPIIPCNLCGSQENLKRAAVKDMLNQWDRQYPGRIETIFTAMQNTAPSQGVDREQFDFVSLTRDPNAPMRGDVAEANLPAFDFLDIANSGRIDLDAAKRIDIVNTYEV
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OXLA_MACLB
Sequence: ADDKNPLEECFREDDYEEFLEIAKNGLEGWYANLGPMRYPVKPSEEGKHDDIFAYEKFDEIVGGMDKKFWEDDGIHGGKETFCYSPMIQKPYQFQHFSEALTAPVGR
What is the function of this protein?
Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids, thus producing hydrogen peroxide that may contribute to the diverse toxic effects of this enzyme (PubMed:16828829).  Shows high activity on L-Met, moderate activity on L-Trp, L-Leu, L-His, L-Phe, L-Arg, L-Ile, low activity on L-Val, L-Glu, L-Lys, L-Gln, L-Asn, L-Tyr, L-Ala, and no activity on L-Asp, L-Ser, L-Pro, L-Gly, L-Thr and L-Cys (PubMed:16828829).  Shows antimicrobial activity inhibiting the growth of both Gram-negative and Gram-positive bacteria (PubMed:16828829).  Also inhibits platelet aggregation induced by ADP or collagen (PubMed:16828829).  Effects of snake L-amino oxidases on platelets are controversial, since they either induce aggregation or inhibit agonist-induced aggregation (By similarity).  These different effects are probably due to different experimental conditions (By similarity).  This protein may also induce hemorrhage, hemolysis, edema, apoptosis, and have antiparasitic activities (By similarity).
What are the official names of this protein?
L-amino-acid oxidase, LAAO, LAO.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GCY5_CAEEL
Sequence: MRLLYFSMVLLWVLGASECQVIPSSRRTLRVGIAAAQDTQSGSIGWASCGGTLPIAVQYLKSKGFLTDFDVEYYMEYTECDRASVAKAGMKFMKEMNVDVVVGPSCGDALAIMGTLSAIYKKLVLGWGFVSDTQLADTNRFPYVASVQPTAQTLGLATSRILEMFQFDRVALLYYKDDQDYCKSVMDDVEATLSDPDLYPVRIVWKGELQSDNEALTRSTLQAVKSRARIVLLCAISGPEKRNYLISIAQQNMTTNEYVHILLTMRSIGYGVQTSLGKKTFANGLTPLWESFTVAPDGNETNARRAAEKMLVIDVNSDVQDAEFLQYLTKNIADAVRNPPMKCNTSECINASSTSMGSYARHLFDVFYLYGMAVSKLNSTDPTVYGNLNLLMPQMVTSFDGMTGRVQIGQNLYRVPTYQLYGLDEKYEQVALVNMTFYNSSSQLSRGYSDEGRSVWHFWDGTRPLDTPICGFSGRYCPVQFWDQYGVLIFVASIVLIFLICIMLMCFGFMIRGRRAEQERLNSEWQIPSIQLIMPQKEKRKPNSRRSLQSGPSTITGESKMTIDGGFHENYTVQMFEKDLVLTTKHHSMQMNKEEKEKFVKLRKLEHDNLNKFIGLSIDGPQFVAVWKMCSRGSLQDIIARGNFSMDGFFMFCIITDIAEGMNFLHKSFLHLHGNLRSATCLVNDSWQVKLTDFGLGALLEEHTPSKKRLLWAAPEVLRGSLTIHQMDPSADVYSFAIIASEILTKREAWDISNRKEGADEILYMVKKGGNRTIRPELILDAEVSPRLTTLVKDCWSEQPEDRPKAEQICKLLSEMTPRGNTNLMDHVFNMLEEYTSTLEVDIEERTKELTLEKKKADILLSRMLPKQVAERLKAGQTVEPEGFDTVTVLFSDVVKFTQLAAKCSPFQVVNLLNDLYSNFDTIIEEHGVYKVESIGDGYLCVSGLPTKNGYAHIKQIVDMSLKFMDYCKSFKVPHLPREKVELRIGINSGPCVAGVVGLSMPRYCLFGDTVNTASRMESNGKPSMIHMSEAAHSLLTDHYPHQYETSSRGEVIIKGKGVMETFWVLGKTDSDTKSLSTRTTPPITDENWPPQMKEDLKKRAVTPYPERQRSGKSKMDTLKVV
What is the function of this protein?
Guanylate cyclase involved in the production of the second messenger cGMP (By similarity).  Unlike other guanylate cyclases expressed in ASE neurons, may not play a role in chemotaxis responses to salt ions mediated by ASE sensory neurons (PubMed:19523832).
What are the official names of this protein?
Receptor-type guanylate cyclase gcy-5.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SWT1A_SORBI
Sequence: MEHIARFFFGVSGNVIALFLFLSPVVTFWRIIRKRSTEDFSGVPYNMTLLNCLLSAWYGLPFVSPNNILVSTINGTGSVIEAIYVVIFLIFAVDRRARLRMLGLLSIVVSIFATVVLVSLLALHGNARKVFCGLAATIFSICMYASPLSIMRLVIKTKSVEYMPFLLSLAVFLCGTSWFIYGLLGRDPFIIIPNGCGSFLGLVQLILYFIYRKNKGPAVPAGKGEAAAAADVEDAKKVAAAVEMADATTTNKAAADTVVGDGKVVASQV
What is the function of this protein?
Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.
What are the official names of this protein?
Bidirectional sugar transporter SWEET1a, SbSWEET1a.
What is the protein family that this protein belongs to?
Belongs to the SWEET sugar transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1659_XANOR
Sequence: MGRGPSIEGRKNASDAKRGKMFTKIIREISVAARAGGGDPSNNPRLRTAMDKGLSANMSKDVIERAIKKSTGELEGVEYEEVRYEGYAPGGVAVIVDCLTDNRVRTVADVRHAFSKCGGNMGTEGSVAFMFKRLGVLSFAAGIDEDTLTDAAIEAGADDVVVYPEDGAIDVLTAPDAFAQVRDALAAAGLEPAHAEIVFRADNDIAVDGDTAVQVRKLLDMLEDLDDVQDVYSNVDQAALGA
What are the official names of this protein?
Probable transcriptional regulatory protein XOO1659.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.