PharMolix/UniProtQA huggingface dataset:
Protein: RSMJ_ECO81
Sequence: MKICLIDETGAGDGALSVLAARWGLEHDEDNLMALVLTPEHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALSDITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPARLLATKRVVVKRPDYAPPLANVATPNAVVTKGHRFDIYAGTPV
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_CORDI
Sequence: MTEGVQNERTGYKRVMLKLGGEMFGGGAVGIDPDVVQNVARQIASVARTGAEIAVVIGGGNFFRGAQLQQRGLDRNRSDYMGMLGTVMNCLALQDFLEQEGIDCRVQTAINMAQVAEPYLPLRAKRHLEKGRVVIFGAGMGMPYFSTDTTAAQRALEIDCEVLLMAKAVDGVYDDDPRTNPDAQLFHQITPREVIEKGLKVADATAFSLCMDNKMPILVFNLLTEGNIARAVAGEQIGTLVQS
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFH_PSEA6
Sequence: MTDKQINLEVAYALPDRQALLEVVVEMGHTVEEAIKASGILQRFDDIDLSKSKVGIWNRTCKLSDVPQDGDRIEIYRPLIADPKEARRRRAEKAKEEGRANKVTGGRA
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: PANB_CORGL
Sequence: MSGIDAKKIRTRHFREAKVNGQKVSVLTSYDALSARIFDEAGVDMLLVGDSAANVVLGRDTTLSITLDEMIVLAKAVTIATKRALVVVDLPFGTYEVSPNQAVESAIRVMRETGAAAVKIEGGVEIAQTIRRIVDAGIPVVGHIGYTPQSEHSLGGHVVQGRGASSGKLIADARALEQAGAFAVVLEMVPAEAAREVTEDLSITTIGIGAGNGTDGQVLVWQDAFGLNRGKKPRFVREYATLGDSLHDAAQAYIADIHAGTFPGEAESF
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTX_VIBCH
Sequence: MYSGAYSFVQISTAAYRISITRLEKTMESLQQQVAQLLEQQPTLLPAAMAEQLNVTEFDIVHALPEEMVAVVDGSHAQTILESLPEWGPVTTIMTIAGSIFEVKAPFPKGKVARGYYNLMGRDGELHGHLKLENISHVALVSKPFMGRESHYFGFFTAQGENAFKIYLGRDEKRELIPEQVARFKAMQQQHKQ
What is the function of this protein?
Binds heme (PubMed:25664785, PubMed:26807477).  Heme is transferred to the heme-degrading enzyme HutZ via a specific protein-protein interaction (PubMed:26807477).
What are the official names of this protein?
Intracellular heme transport protein HutX, Heme-binding protein HutX.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPB_HAHCH
Sequence: METVASTQVQTLIVRRFGLVSYEPVWRAMQDFTQQRDAETTDEVWLLQHEPVFTQGQAGDAEHVLFPGDIPVVQVDRGGQVTYHGPGQLMVYLLLDLRRLKMGARDLVTMIENTLVDTLAGYGIEAHARKDAPGVYVGDAKIASLGLRIRRGSSFHGLALNVDMDLEPFLRINPCGYQGLRMTQIKEFVPDVSWASVADAWLSQFVRAAGFQSVVEQRGLPGDE
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL37_METM7
Sequence: MTKGTPSQGKHNKGSNHIVCRRCGRRSFHVRKKVCAACGFGKSSKIKRFAWQWKKVTGKGNRVK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L37e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL37 family.
Protein: ARGC_ACIF5
Sequence: MIRAGIVGGTGYTGVELLRLLLPHPEVELVAITSRAEAGQRVDEHFPNLRGHCNLSYTAPDPAILGTLDVVFFATPHGVAMDSAPKLLAEGVRIIDLGADFRLPDAEVFAQWYGMAHRAPEVLGEACYGLPEYYRTKISEARLIANPGCYPTAVILGLAPLLAEGLLQEDTLIADCKSGVSGAGRSAKVGLILPETADSVSAYGVGGHRHRPEIEAVLSDISGTPLELQFTPHLMPMIRGIHATLYGRLAQPMSDAALQDLFATRYASEPFVDVLPFGSHPATRSVRGANMCLIAVHQPRPGQVVVLSVIDNLVKGAAGQAIQNMNRLFSLAEDAGLMQIALLP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOC_AQUAE
Sequence: MIDVRKYIDNAALKPHLSEKEIEEFVLKSEELGIYAVCVNPYHVKLASSIAKKVKVCCVIGFPLGLNKTSVKVKEAVEAVRDGAQELDIVWNLSAFKSEKYDFVVEELKEIFRETPSAVHKVIVETPYLNEEEIKKAVEICIEAGADFIKTSTGFAPRGTTLEEVRLIKSSAKGRIKVKASGGIRDLETAISMIEAGADRIGTSSGISIAEEFLKRHLI
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_BURO1
Sequence: MLDPRARTLLKTLIERYIADGQPVGSRTLSRYSGLELSPATIRNVMSDLEELGLVSSPHTSAGRVPTPRGYRLFVDTMLTVEAPIDAEAVARQVQNTLQAGEPQQRVVAAAASVLSNLSQFAGVVLTPRRSHVFKQIEFMRLSDKRILLIIVTPEGDVQNRMLATPRDYSPSQLTEASNYINAHFAGLSFDEVRRRLRDEIDQLRGDMTTLMHAAVTASTEVPDTEDTVLISGERNLLEVADLSSDMARLRKLFDVFDQKTGLLQLLDVSSHAQGVQIFIGGESTLVPIEEMSVVTAPYEVNGQIVGTLGVIGPTRMAYNRVIPIVDITARLLSLTLSQQ
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: C_SPV4
Sequence: MDKLISLKDVMRFIFKFGLPGLCIAVGLIVMVANKWLGIPWPCYVIVGSVSLSFGLILFIVQTIKEIIIYRKEKKDENIYSKK
What is the function of this protein?
Plays a central role in the packaging of viral DNA into phage procapsid, which occurs in the late stage of infection.  Can interact with the replicative complex after the completion of one round of DNA synthesis.  When protein ORF5 is bound to the replicative form, the complex becomes accessible to procapsid and serves as a DNA packaging apparatus (By similarity).
What are the official names of this protein?
Protein ORF5.
What is the protein family that this protein belongs to?
Belongs to the microviridae C protein family.
Protein: HTPX_RHILW
Sequence: MNLVRTAMLLAFMTALFMFVGFLIGGRAGMMIAFVIAAGMNFFSYWNSDRMVLSAYRAQQVDERNAPEFFAIVRDLARNAGLPMPKVYLYDSPQPNAFATGRNPENAAVAASTGLLQALSPEEVAGVMAHELAHIQNRDTLTMTITATLAGAISMLGNFAFFFGGNRENNNNPLGFVGVLVAMIVAPLAAMLVQMAISRTREYSADRRGAEICGNPLWLASALGKIARGAAHVPNEDAERNPATAHMFIINPLSGERMDNLFSTHPNTENRIAALQDMAQGGMNVSTPPVRAANPSRKSRSVPDTGLGRGGSQPPKGPWS
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RBP_STRCA
Sequence: KKYSCLEGETHKLKPSPEPNMQECTLYSGSSCCYA
What is the function of this protein?
Required for the transport of riboflavin to the developing oocyte.
What are the official names of this protein?
Riboflavin-binding protein, RBP.
What is the protein family that this protein belongs to?
Belongs to the folate receptor family.
Protein: DUS3_CHAGB
Sequence: MEPQDRTKRPQEEDNGVPIDGHNGSNSEPAAKKIKLDSPSSADSRAKGVAPIKAEYLLFPPGQKAKPTQSEAEADDNDDDAAEGRTAPTPQETQQAPQKDGKRKSQRGQNKEREFGTFSDAQRLCNTIAWTPEFSPRPCKHGDRCNALHDLRKYLKEGRRPDITTFGGKCPVWEKYGKCPSGWRCLFVHSHMDEIKHEDGRSELVLVGDASKAPEGGEEAAGEIKPGVVNMVPVGIKYDLSKKRIPLEKSEQYLAWLAKDTKHLAKHYQKHKDDETNPNDYRAQYVEPPFKPSEKRRLYFGRETPVLAPLTTQGNLPFRRLCVELGAQVTYSEMALGLPLLQGLKADWTLMRAHESEIVPPRFNPGGPIVQGYDNSKDVKFGAQIAANAPWVAVKATEALSQLLPHLRLVDLNCGCPVDAVFKSGSGSALLDSHSKLERMIRGMNAVSGEVPITAKIRMGSRDGKLTAQKLVERLALGSEDLRDMIGAPGCAAVTLHGRTRLQRYTKAADWGYIAECAALIKQFNEKSNDLADTIREADENTLPNGGKMYFLGNGDCYSHVEYFDHVDNAKVDSVMIGRGALVKPWVFEEIEKGQYLDKSSSERLTYIEKFVRYGMEAWGSDELGLNYTRRFLLEFLSFFCRYVPIGLLERLPPNLNERPPAYRGRDDLETLFASKNYKDWIKISEMFLGPAPPGFKFQPKHKSNSYEIEAEG
What is the function of this protein?
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.  Specifically modifies U47 in cytoplasmic tRNAs (By similarity).  Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation (By similarity).
What are the official names of this protein?
tRNA-dihydrouridine(47) synthase [NAD(P)(+)], mRNA-dihydrouridine synthase DUS3, tRNA-dihydrouridine synthase 3.
What is the protein family that this protein belongs to?
Belongs to the Dus family. Dus3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MP64_MYCBO
Sequence: MRIKIFMLVTAVVLLCCSGVATAAPKTYCEELKGTDTGQACQIQMSDPAYNINISLPSYYPDQKSLENYIAQTRDKFLSAATSSTPREAPYELNITSATYQSAIPPRGTQAVVLKVYQNAGGTHPTTTYKAFDWDQAYRKPITYDTLWQADTDPLPVVFPIVQGELSKQTGQQVSIAPNAGLDPVNYQNFAVTNDGVIFFFNPGELLPEAAGPTQVLVPRSAIDSMLA
What are the official names of this protein?
Immunogenic protein MPB64, Antigen MPB64.
What is the protein family that this protein belongs to?
Belongs to the RsiV family.
What are the subcellular locations of this protein?
Secreted.
Protein: DABA_ACICJ
Sequence: MTNKIPSSWPNPQALTIVMDRAARAIPPAWPLASSVAVNPFLGQTEEPLAKVGARLARVAGARVTMPRRWYAQKIAAGVISEADLEAAIASAPVGSRSVDVSTLKSAANAEALPPKALPTIAELAAYASGIDWPGIIAERFGAWAAGYFDEGQALWAAPKGKRAYAAWRAVAAHDLTPEIAGLRDFALNVSEAPETALAIVERVVARLGLPADAAETYFHQMLMTLGGWAHYARYKLWQAELAGGADETITDFLAIRLIWEEALFLQYDAEIAAAWRGVRTAHAAPVEPTRDIAIDAILQAAAEHAAQRALAQTLAEHSPHALNDRPALQTAFCIDVRSEVFRRALESMDPRIQTIGFAGFFGLTTSHRRFASDVEERRLPVLLNPALRSYSGGLEAHAKDQSTRVKTRARRAWGRFKLAAVSSFAFVEATGPVYVGKLLADALGLQVSPPPSDPSPRLDPAPDLATRVETAETVLRAMSLTRDFARLVLFVGHGANVVNNPHASALHCGACGGYSGEVNARLLASLLNDAEVRGGLSRNGIEIPDDTHFVAALHDTTTDDVTLYLDDHPSAAHRGDLEQARLWLTSAGKIARTERALRLPRAASDASLPKRGRDWSETRPEWALAGCQAFIAAPRRRTAGKSLGGRAFLHDYDWKQDKSFSVLELILTAPVVVASWISLQYYGSTVAPDVFGGGNKLLHNVTGGIGVVEGNGGLLRVGLPWQSVHDGERYAHDPLRLSVCIEAPREAMSEILGRHADVRALFDNGWLHLFALDEAGRMAWRYAGDLQWSAIGNLDAPAASQRLKVSV
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GREA_STRMU
Sequence: MSEKTYPMTLAEKEQLEQELEELKLVRRPEVIERIKIARSYGDLSENSEYEAAKDEQAFVEGQISSIETKIRYAEIVDSDAVAKNEVAIGKTVIVREVGTNDEDTYSIVGAAGADVFAGKISNESPIAQALIGKKTGDKVMIESPAGSYQVEIVKVKKTK
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: MP83_MYCTO
Sequence: MINVQAKPAAAASLAAIAIAFLAGCSSTKPVSQDTSPKPATSPAAPVTTAAMADPAADLIGRGCAQYAAQNPTGPGSVAGMAQDPVATAASNNPMLSTLTSALSGKLNPDVNLVDTLNGGEYTVFAPTNAAFDKLPAATIDQLKTDAKLLSSILTYHVIAGQASPSRIDGTHQTLQGADLTVIGARDDLMVNNAGLVCGGVHTANATVYMIDTVLMPPAQ
What are the official names of this protein?
Cell surface glycolipoprotein MPT83, Lipoprotein p23.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Secreted, cell wall. Secreted.
Protein: MURG_DESRM
Sequence: MRAIITGGGTGGHIYPALAIARGLQSRFSKVQILYVGTNRGLEADIVPKANFPFQAITVSGLQRKISLENFKVLWQAYRGYREAVGIIKTFNPDVVIGTGGYVCGPVVMAAARRGIPTLIHEQNAFPGITNRILSKFADQVTVTFEDSIRYFGNKDNITLTGLPVRPEILQAERQTALEMFKLKNDKLTLLVFGGSRGARKINQAMVETIKKYGNDERLQILHATGQAGYEEFMQELKDNGISLEHYGNIIIKPYIYNMHEALVAADMVVSRAGAATLAELTVLGLPSILIPYPYASENHQEHNARALAERGAAVLIKDSQLTGEKLIQAIKDMLQNKEKLKNMAKSSQKLGRPEALSDIIKCVEKILPRQQ
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FBX30_MOUSE
Sequence: MEEEVQQHSHCMNCVSRRCMTRPEPGVSCDLIGCPLVCGAVFHSCKADEHRLLCPFERVACLNRNFGCPFTLARNKVAEHLEMCPASVVCCTMEWNRWPVSYSDRKSYESLSRDVDEVAQLDMALALQDQRMLLESLKVATMMSKATDKISEPREQISVKSSVQEIPRTNGLVSVDEESYGALYQATVETTRSLAAALDILNSATRDIGMLNTSLHATANEMDEENNKESFQDKNLKDQDHLDEGEIGAVGGVDYSGTSQNAQAEQNGSSDLLCDLNPSSNGTSALCNGFPLEKMCIQVKGQDQNFHGDSTESNITNGDCVEADGTSEPSSSLVVPEQLREISPFSALPDSTFQQILMPDEDDEKDLCWKKVDLGDLKDVNGSPFSHAPSFKFLSNSWYIPKEDKAVDTSDLEVAEDPMGLQGIDLITAALLFCLGDSPGGRGISDSRMTDVYHVDFGTQTFSLPSAILATNTMVGEIASASACDHANPQLSNPSPFQTLGLDLVLECVARYQPKQRSMFTFVCGQLFRRKEFSSHFKNVHGDIHAGLNGWMEQRCPLAYYGCTYSQRRFCPSTQGAKIIHDRHLRSFGVQPCVSTVLEEPSRNCVLGLRSDHLSSLPFEVLQHIAGFLDGFSLCQLACVSRLMRDVCGSLLQSRGMVILQWGKKKYPEGNSSWQIKEKVWRFSTAFCSVNDWKFADILSMADHLKNCSYNVIEKREEAIPLPCMCVTRELTKEGRSLRSVLKPVL
What is the function of this protein?
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.  Required for muscle atrophy following denervation.
What are the official names of this protein?
F-box only protein 30, Muscle ubiquitin ligase of SCF complex in atrophy-1, MUSA1.
Protein: NS1_INBGL
Sequence: MVDNMTTTQIEVGPGATNATINFEAGILECYERLSWQRALDYPGQDRLHRLKRKLESRIKTHNKSEPESKRMSLKERKAIGVKMMKVLLFMDPSAGIEGFEPYCVKNPLTRKCPNCDWAYYPPTPGKYLDDIEEEPEDVDHPIEVVLRDMNNKDARQKIKDEVNTQREGKFCLTIKRDICNVMSLRVLVNGTFLKYPNGDKSLSTLHRLNAYDQDGGLVAKLVATDDLTVEDEKDGHRILNSLFERFDEGHPKPIRAAETAVGVLSQFGQEYRLSPEEGDN
What is the function of this protein?
Binds and inhibits the conjugation of the ubiquitin-like G1P2/ISG15 protein to its target proteins.  Since G1P2/ISG15 is an early antiviral protein, NS1 may inhibit the host antiviral response.  Prevents EIF2AK2/PKR activation, either by binding double strand RNA or by interacting directly with EIF2AK2/PKR.  Also binds poly(A) and U6 snRNA.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza B viruses NS1 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: EIF3D_COCIM
Sequence: MAPLSLTDIVSALPSEEDAWGPPVPTGNHLDGVPYAPFSKGDKLGRMADWGADSKDSRERGRQAYNRNYRDQQVYGAGTSSLFAVQVAEDESSFSVVDNTRTSVKTRGFGRGGGTIFRGRGQRGGAQRGRGGAFQRPAGGRGGQAGGDRYYDQRGGRGNRGRRFGWKDYDKPQRNRDSSVAIRPEWSMLEEIDFSRLSKLNLETPDGEDLDNYGFLYYYDRSYDKAPVKNTERRLRALERAAYNVTTSADPVIQELAEKDEATVFATADILSMLMCASRSVYSWDIVIVKHGNKIYFDKRDNASIDLVTVNENAADAPMEASEGQAKHDSINTPGALALEATIINHNFALQTVVESDSAKVEFSHPNPFYNPSEETEPLASKGFKYRRFDLSLEKDEEPVQIIVRTEIDAVLKNNISGEDQHVTLKALNEFDHKAQGAGGALDWRSKLYSQRGAVVATEMKNNNVKLARWTTQAILAKSDVMKLGFVTRANPRSATAHMILGVIGYKPREFALQMNLNMANGWGIVRTIIDLVNSLDARDEEEGDDAQEDKIKKYILVKDPNKSVVRLYSVPANTFEEEDDTGAKAEKDEESEEKDEE
What is the function of this protein?
mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit D, eIF3d.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO3A_STAAC
Sequence: MVAYLNIHTAYDLLNSSLKIEDAVRLAVSENVDALAITDTNVLYGFPKFYDACIANNIKPIFGMTIYVTNGLNTVETVVLAKNNDGLKDLYQLSSEIKMNALEHVSFELLKRFSNNMIIIFKKVGDQHRDIVQVFETHNDTYMDHLSISIQGRKHVWIQNVCYQTRQDADTISALAAIRDNTKLDLIHDQEDFGAHFLTEKEINQLDINQEYLTQVDVIAQKCDAELKYHQSLLPQYETPNDESAKKYLWRVLVTQLKKLELNYDVYLERLKYEYKVITNMGFEDYFLIVSDLIHYAKTNDVMVGPGRGSSAGSLVSYLLGITTIDPIKFNLLFERFLNPERVTMPDIDIDFEDTRRERVIQYVQEKYGELHVSGIVTFGHLLARAVARDVGRIMGFDEVTLNEISSLIPHKLGITLDEAYQIDDFKKFVHRNHRHERWFSICKKLEGLPRHTSTHAAGIIINDHPLYEYAPLTKGDTGLLTQWTMTEAERIGLLKIDFLGLRNLSIIHQILTQVKKDLGINIDIEKIPFDDQKVFELLSQGDTTGIFQLESDGVRSVLKKLKPEHFEDIVAVTSLYRPGPMEEIPTYITRRHDPSKVQYLHPHLEPILKNTYGVIIYQEQIMQIASTFANFSYGEADILRRAMSKKNRAVLESERQHFIEGAKQNGYHEDISKQIFDLILKFADYGFPRAHAVSYSKIAYIMSFLKVHYPNYFYANILSNVIGSEKKTAQMIEEAKKQGITILPPNINESHWFYKPSQEGIYLSIGTIKGVGYQSVKVIVDERYQNGKFKDFFDFARRIPKRVKTRKLLEALILVGAFDAFGKTRSTLLQAIDQVLDGDLNIEQDGFLFDILTPKQMYEDKEELPDALISQYEKEYLGFYVSQHPVDKKFVAKQYLTIFKLSNAQNYKPILVQFDKVKQIRTKNGQNMAFVTLNDGIETLDGVIFPNQFKKYEELLSHNDLFIVSGKFDHRKQQRQLIINEIQTLATFEEQKLAFAKQIIIRNKSQIDMFEEMIKATKENANDVVLSFYDETIKQMTTLGYINQKDSMFNNFIQSFNPSDIRLI
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The alpha chain is the DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase III subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMMN_ECOLX
Sequence: MHNTLLEKIIAYLSLPGFHSLNNPPLSEAFNLYVHTAPLAATSLFIFTHKELELKPKSSPLRALKILTPFTILYISMIYCFLLTDTELTLSSKTFVLIVKKRSVFVFFLYNTIYWDIYIHIFVLLVPYRNI
What are the official names of this protein?
Colicin-N immunity protein, Microcin-N immunity protein.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GARL_SHIB3
Sequence: MESLPVFPNKFKAALAAKQVQIGCWSALSNPISTEVLGLAGFDWLVLDGEHAPNDISTFIPQLMALKGSASAPVVRVPTNEPVIIKRLLDIGFYNFLIPFVETKEEAEQAVASTRYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDNVDAIAATEGVDCIFVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAPVEADARRYLEWGATFVAVGSDLGVFRSATQKLADTFKK
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.
What are the official names of this protein?
5-keto-4-deoxy-D-glucarate aldolase, KDGluc aldolase, KDGlucA, 2-dehydro-3-deoxy-D-glucarate aldolase, 2-keto-3-deoxy-D-glucarate aldolase, 5-dehydro-4-deoxy-D-glucarate aldolase, Alpha-keto-beta-deoxy-D-glucarate aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
Protein: UVRB_NEIG1
Sequence: MEVIRYPNSPFKLHQPFPPAGDQPTAIAGLIEGLSDGLAYQTLLGVTGSGKTYTMANVIAQSGRPAIIMAHNKTLAAQLYAEMREFFPENAVEYFVSYYDYYQPEAYVPSRDLFIEKDSAINEHIEQMRLSATKNLMTRDDVIIVATVSAIYGIGDPTEYQQMVLSVKEGDTIEQRDIIATLVSMQYERGDLDFKRGSFRVRGDVIDVYPAESSENALRISLFDDEIDRLDMFDPLSGSLHQRVGRYTVFPSSHYVTPRDTVLRACESIKEELRERIEFFAREQRPVEQQRIEQRTRFDLEMLYEMGFCKGIENYSRHFSGKKEGEPPPTLMDYLPDNAIMFIDESHVTVTQIGGMYKGDASRKQNLVDYGFRLPSARDNRPLKFHEFEKVMPQTVFVSATPAKYEEEHAGQVVEQVVRPTGLVDPQTIIRPVATQVDDLMSEINDRIQKGERVLVTTLTKRMAEQLTDYYSELGIKVRYLHSDIDTVERVEIIRDLRLGLFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSHRSLIQTIGRAARNVNGVAILYADKITDSMKAAVDETERRREKQIKFNEEHGIVPQQIKKQVKDIIDGVYHEEDSGKGRRQGKNKVKVGEIHNEEDAIKEIAKLEKAMQQAARDLQFEEAAVLRDRISNIKENLLFGAE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CB2G_SOLLC
Sequence: MATSTMALSSSTFAGKAVKLSPSSSEITGNGRVTMRKTATKAKPASSGSPWYGPDRVKYLGPFSGESPSYLTGEFPGDYGWDTAGLSADPETFAKNRELEVIHCRWAMLGALGCVFPELLARNGVKFGEAVWFKAGSQIFSEGGLDYLGNPSLVHAQSILAIWACQVVLMGAVEGYRIAGGPLGEVVDPLYPGGSFDPLGLADDPEAFAELKVKEIKNGRLAMFSMFGFFVQAIVTGKGPLENLADHLADPVNNNAWAFATNFVPGK
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.
What are the official names of this protein?
Chlorophyll a-b binding protein 3C, chloroplastic, LHCII type I CAB-3C, LHCP.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: PSAJ_ORYSJ
Sequence: MRDIKTYLSVAPVLSTLWFGALAGLLIEINRLFPDALSFPFFSF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ST_POVSM
Sequence: MDYTLTREESKLLMELLGLPMEQYGNFPLMRKAFLQKCKIMHPDKGGDEQTAKMLISLYKKLESEVKSLNTDDGFSTEEVCKISKLTYIKDWLTCSFGSFSCKCLFCLLLKSHKQELTKKPKVWGDCLCFKCYTLWFGLQYTVDIYQSWQALIGVTLFKNLNI
What is the function of this protein?
Promotes efficient viral genome replication by accelerating both G1 and S phase progression of the cell cycle.  Inhibits host PP2A by binding to the A subunit, thereby displacing lower affinity regulatory B subunit.  Inactivation of PP2A in turn results in the transactivation of cyclin A and cyclin D1 promoters.  Late during the infection cycle, ST may induce dephosphorylation of host MTOR, leading to the inhibition of cap-dependent translation.  May establish and maintain high levels of viral genomes during persistent infection in cell culture.
What are the official names of this protein?
Small t antigen, ST, ST-AG.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.