PharMolix/UniProtQA huggingface dataset:
Protein: NUCB1_PONAB
Sequence: MPPSGPQGTLLLLPLLLLLLLRAVLAVPLERGAPNKEETPATESPDTGLYYHRYLQEVIDVLETDGHFREKLQAANAEDIKSGKLSRELDFVSHHVRTKLDELKRQEVSRLRMLLKAKMDAEQDPNVQVDHLNLLKQFEHLDPQNQHTFEARDLELLIQTATRDLAQYDAAHHEEFKRYEMLKEHERRRYLESLGEEQRKEAERRLEEQQRRHREHPKVNVPGSQAQLKEVWEELDGLDPNRFNPKTFFILHDINSDGVLDEQELEALFTKELEKVYDPKNEEDDMREMEEERLRMREHVMKNVDTNQDRLVTLGEFLASTQRKEFGDTGEGWETVEMHPAYTEEELRRFEEELAAREAELNAKAQRLSQETEALGRSQGRLEAQKRELQQAVLHMEQRKQQQQQQQQQGHKAPAAHPEGQLKFHPDTDDVPVPAPAGDQKEVDTSEKKLLERLPEVEVPQHL
What is the function of this protein?
Major calcium-binding protein of the Golgi which may have a role in calcium homeostasis (By similarity).  Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates alpha subunits of guanine nucleotide-binding proteins (G proteins) (By similarity).
What are the official names of this protein?
Nucleobindin-1.
What is the protein family that this protein belongs to?
Belongs to the nucleobindin family.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network membrane; Peripheral membrane protein; Lumenal side. Cytoplasm. Secreted. Note=A small fraction of the protein may be cytoplasmic.
Protein: DNAA_YERPG
Sequence: MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPNRFVLDWVRDKYLNNINGLLNDFCGTEVPLLRFEVGSKPAARAHNNPVTASVSAPVAPVTRSAPMRPSWDNSPAQPELSYRSNVNPKHTFDNFVEGKSNQLARAAARQVADNPGGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKANAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFIAKRLRSNVRELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVADLLSKRRSRSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREESHDIKEDFSNLIRTLSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPC1_DROME
Sequence: MSEGSDNNGDPQQQGAEGEAVGENKMKSRLRKGALKKKNVFNVKDHCFIARFFKQPTFCSHCKDFICGYQSGYAWMGFGKQGFQCQVCSYVVHKRCHEYVTFICPGKDKGIDSDSPKTQHNFEPFTYAGPTFCDHCGSLLYGIYHQGLKCSACDMNVHARCKENVPSLCGCDHTERRGRIYLEINVKENLLTVQIKEGRNLIPMDPNGLSDPYVKVKLIPDDKDQSKKKTRTIKACLNPVWNETLTYDLKPEDKDRRILIEVWDWDRTSRNDFMGALSFGISEIIKNPTNGWFKLLTQDEGEYYNVPCADDEQDLLKLKQKPSQKKPMVMRSDTNTHTSSKKDMIRATDFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKKDVIIQDDDVECTMIEKRVLALGEKPPFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLHTKGILYRDLKLDNVLLDADGHVKIADFGMCKENIVGDKTTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLYEMLVGQPPFDGEDEEELFAAITDHNVSYPKSLSKEAKEACKGFLTKQPNKRLGCGSSGEEDVRLHPFFRRIDWEKIENREVQPPFKPKIKHRKDVSNFDKQFTSEKTDLTPTDKVFMMNLDQSEFVGFSYMNPEYVFSP
What is the function of this protein?
PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins (By similarity).  PKC also serves as the receptor for phorbol esters, a class of tumor promoters (By similarity).  Acts in a hh-signaling pathway which regulates the Duox-dependent gut immune response to bacterial uracil; required for the activation of Cad99C and consequently Cad99C-dependent endosome formation, which is essential for the Duox-dependent production of reactive oxygen species (ROS) in response to intestinal bacterial infection (PubMed:25639794).
What are the official names of this protein?
Protein kinase C, brain isozyme, PKC, dPKC53E(BR).
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
Protein: CO8B_RABIT
Sequence: MKKSWTWTWRVPAELLLLCAALGCLCVPGSRSERPRSLEPTVVNRSLAKSRHSRSVDATPMPIDCELSSWSSWTMCDPCQKKRYRHAYLLRPSQFNGEPCNFSDKEVEDCATSRPCRSQVRCEGFVCAQTGRCVNRRLLCNGDNDCGDQSDEANCRKIYKKCHHEMEQYWAIGSLASGINLFTNSLEGPVLDHRYYAGGCNPHYILDMRFRKPYNVESYTPQTQGKYKFALAEYESYSDFERNVMEKTYSKSTFNLGFKIPSIFEFGINTESDQLMNYISRTKRFSHTKSKFLHARSALEVAHYKLKPRNLMLHYDFLQRVQRVPLEYSYGEYRDLFRDFGHHFITEAVLGGIYEYTLIMNKEAMERADYSLNDVQACAKNDFKLGAAIEEVYVSLGVSTSKCRGILNEIKDRNKRDTMVQDLVVLVRGGASEHITALAYSDLPTADLMQEWGDAVQYNPAIIKIKVEPLYELVTATDVAYSSTVKQNMRQALEEFQGEVSPCRCAPCQGNGVPVQKGSRCDCICPVGFQGSACEITSRKNVPIDGRWSCWSRWSSCSGGQKTRRRQCNNPAPQDGGSPCSGPASETLAC
What is the function of this protein?
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
What are the official names of this protein?
Complement component C8 beta chain, Complement component 8 subunit beta.
What is the protein family that this protein belongs to?
Belongs to the complement C6/C7/C8/C9 family.
Protein: PANB_RHOPS
Sequence: MSVQSAIKRKTAPDIRARKGGDPIVMLTSYHAHTASLVDRYCDVILVGDSLGNVMHGFETTVPVTLEMMILQGHAVMRGSQHALVVVDMPFGSYEASKEQAFHSAARILKETQCGAVKLEGGVRMAETIAFLTERGIPVMGHIGLTPQSINTLGSFRAQGREEGSWEPIEADARAVSDAGAFSVVVEAVAEPLGRKITETIAIPTIGIGASAACDGQVLVLEDMLGLSPRAPKFVKRYGELGPGIEAAIKGFAEEVRSRAFPGPEHVYGMKTKS
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_BART1
Sequence: MTDLTTLTIAQARDALITKKLKATELTEAYLKAIELANPTLNAYVTITAEQARKMAAESDRRLAKGERGLLEGIPLGIKDLFATHGVHTQACSNILDGFKPNYESTITANLWQDGAVMLGKLNMDEFAMGSSNETSYYGPVISPWRKKDSNEKLVPGGSSGGSAAAVAAQICAGATATDTGGSIRQPAAFTGTVGIKPTYGRCSRWGVVAFASSLDQAGPIARDVRDCAILLRSMASFDEKDSTSVNLPVPDYESYLGKSIKGMKIGIPKEYYLAGMSQEIIDLWQKGINWLKEAGAEIRDISLPHTKYALPSYYIIAPAEASSNLARYDGVRFGLRVPGKDIIEMYENTRSVGFGDEVKRRILIGTYVLSSGYYDAGYLRAQKVRTLVKRDFDQCFDSGVDAILTPATPTPAFGIADEKIKNDAVAMYLNDIFTVPVNMAGLPGISVPAGLSSNGLPLGLQLIGKPFAEEVIFQIAHIIEQEAGIFCAKKWWI
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: TPPD_ARATH
Sequence: MTNHNALISDAKGSIGVAVRVPNQSLFSPGGGRYISIPRKKLVQKLEADPSQTRIHTWIEAMRASSPTRTRPGNISPLPESDEEDEYSSWMAQHPSALTMFEEIAEASKGKQIVMFLDYDGTLSPIVENPDRAYMSEEMREAVKGVARYFPTAIVTGRCRDKVRRFVKLPGLYYAGSHGMDIKGPSKRNKHNKNNKGVLFQAANEFLPMIDKVSKCLVEKMRDIEGANVENNKFCVSVHYRCVDQKDWGLVAEHVTSILSEYPKLRLTQGRKVLEIRPTIKWDKGKALEFLLESLGFANSNDVLPIYIGDDRTDEDAFKVLRNKGQGFGILVSKIPKETSATYSLQEPSEVGEFLQRLVEWKQMSLRGR
What is the function of this protein?
Removes the phosphate from trehalose 6-phosphate to produce free trehalose.  Trehalose accumulation in plant may improve abiotic stress tolerance (By similarity).
What are the official names of this protein?
Probable trehalose-phosphate phosphatase D, AtTPPD, Trehalose 6-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the trehalose phosphatase family.
Protein: LRGA_STAA8
Sequence: MVVKQQKDASKPAHFFHQVIVIALVLFVSKIIESFMPIPMPASVIGLVLLFVLLCTGAVKLGEVEKVGTTLTNNIGLLFVPAGISVVNSLGVISQAPFLIIGLIIVSTILLLICTGYVTQIIMKVTSRSKGDKVTKKIKIEEAQAHD
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like proteins CidA and/or CidB.  The LrgAB and CidAB proteins may affect the proton motive force of the membrane.  Increases tolerance to penicillin possibly by inhibiting the formation of the CidAB holin-like complexes within the membrane, thus reducing penicillin-induced lethality.  Possibly plays a role in programmed cell death (PCD), triggering PCD in response to penicillin, and possibly other antibiotics, and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgA.
What is the protein family that this protein belongs to?
Belongs to the CidA/LrgA family. LrgA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NAGB_STRE4
Sequence: MKIIRVQDQLEGGKVAFSLLKESLAKGATTLGLATGSTPITFYQELVNSDLDCSALTSINLDEYVGLPVENDQSYDYFMRDQLFNAKPFKESFLPNGLADDLEAEVKRYDQVIAEHPIDFQILGIGRNGHIGFNEPGTSFAEKTHVVDLQASTIEANSRFFASIDDVPKQAISMGIASIMASKMIVLLAFGKEKAAAIKGMVSGPVTEALPASVLQQHDNVVVIIDEAAASELD
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: RL33_CLOK5
Sequence: MRVKVILACTECKQRNYNTMKNKKNNPNRLEIKKYCPFCNKHTVHKQTK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: ACT2_DIBDE
Sequence: MGDEEVQALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTRIMFETFNTPAMYVGIQAVLSLYASGRTTGIVLDSGDGVTHSVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPESLFQPSFLGMESAGIHESTFNAIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITSLAPSTMKIKIVAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPGIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin-2.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: SYC_BACC1
Sequence: MTIHIYNTLTRQKEEFIPLEENKVKMYVCGPTVYNYIHIGNARPPMVFDTVRRYLEYKGYDVQYVSNFTDVDDKLIKAANELGEDVPTIADRFVEAYFEDVTALGCKHATVHPRVTENMDIIIEFIQELVNKGYAYESEGDVYFRTKEFEGYGKLSHQPIADLRHGARIEVGEKKQDPLDFALWKAAKEGEIFWESPWGQGRPGWHIECSAMARKYLGDTIDIHAGGQDLAFPHHENEIAQSEALTGKTFARYWMHNGYININNEKMSKSLGNFILVHDIIKQYDPQLIRFFMLSVHYRHPINFSEELLQSTNNGLERIKTAYGNLKHRMESSTDLTDHNEKWLADLEKFQTAFEEAMNDDFNTANAITELYNVANHANQYLLEEHTSTVVIQAYVKQLETLFDILGLELAQEELLDEEIEALIQKRIEARKNRDFALSDQIRDDLKDRNIILEDTAQGTRWKRG
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_MANSM
Sequence: MIDPNLLRNNLAEVAATLKLKRNFILDTKELAELEEQRKALQVETETLQAKRNARSKAVGAAKARGENIAPLLAEMDDMGHELATVKAELDEILAELNTIALTIPNLPADEVPLGKDDSENKEISRWGTPRQFDFEIKDHVTLGENLAGGIDFAAGAKLSGARFAVMKGQVAKMHRALAQFMLDLHTEQHGYTETYVPYLVNHTTLYGTGQLPKFGEDLFHTTPLEGEVPYALIPTAEVPVTNLVRDEILNTEDLPIRMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVDPDKSMEALEELTAHAEKVLQLLGLPYRKMLLCTGDMGFGSCKTYDLEVWVPAQDTYREISSCSNMWDFQARRMQARCRSKTDKKTRLVHTLNGSGLAVGRTLVAVLENYQNEDGSVTVPEVLRPYMGGLEVIGK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEAD_BUCBP
Sequence: MTHTNMTFSSFGLNSCIITALNDIGYVQPSPIQAACIPYLIKGKDVLGMAQTGSGKTAAFALPLLHNIKLDVRVPQILVLTPTRELAVQVAEAFSNFSKKLIGVHVLALYGGQRYDLQLKSLRKGPQIIVGTPGRLLDHLKRRTLSLSNLHSLVLDEADEMLRMGFIEDVETIMTEIPDRHQTALFSATMPEAIRRISRRFMKNPKEIRIQSNITTRPDIQQSYWMVYGKKTDALIRFLEAEDFSATIIFVRTKNATLEVSEVLERYGYNSAALNGDMNQSLREQTLEKLKDGRLDILIATDVAARGLDVDRISFVINYDIPMDSESYVHRIGRTGRAGRKGKALLFVENRERRLLRNIERAMNISISEVNLPKSDFLSKRRLEKFAQKVQIQLDSKDLHEYRGLLPKLQPNNNSLDIESLAAALLKMAQGERSLIVKPESIVRARHLKIKDTYRNNNYKSLNYVSRYNRDKNVDLYRIDVGRNDGVEVRHIVGAIANEGDISSRKIGNVRLFSNYSTIELPKGLSNTLPKTFIRTKILNKFINIKLLYNSNFKGNYNDIKDVKVYNSNKLRSKKMNNKKFVSSGVRKKIKTNISCNRRRSV
What is the function of this protein?
DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
What are the official names of this protein?
ATP-dependent RNA helicase DeaD, Cold-shock DEAD box protein A.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTNA_HUMAN
Sequence: MIEDSGKRGNTMAERRQLFAEMRAQDLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNTELNVSRLEAVLSTIFYQLNKRMPTTHQIHVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIMDKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYTEQSARSCFSQQKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHAGGSHSNQHQMKEYTSWKSPAKKLTNALSKSLSCASSREPLHPMFPDQPEKPLNLAHIVDTWPPRPVTSMNDTLFSHSVPSSGSPFITRSSPPKDSEVEQNKLLARAAPAFLKGKGIQYSLNVADRLADEHVLIGLYVNMLRNNPSCMLESSNRLDEEHRLIARYAARLAAESSSSQPPQQRSAPDISFTIDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKTQGAGSPRSSPSHTISRPIPMPIRSASACSTPTHTPQDSLTGVGGDVQEAFAQSSRRNLRNDLLVAADSITNTMSSLVKELNSEVGSETESNVDSEFARTQFEDLVPSPTSEKAFLAQIHARKPGYIHSGATTSTMRGDMVTEDADPYVQPEDENYENDSVRQLENELQMEEYLKQKLQDEAYQVSLQG
What is the function of this protein?
May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors.
What are the official names of this protein?
Dystrobrevin alpha, DTN-A, Alpha-dystrobrevin, Dystrophin-related protein 3.
What is the protein family that this protein belongs to?
Belongs to the dystrophin family. Dystrobrevin subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Synapse. Cell membrane. Note=In peripheral nerves, colocalizes with MAGEE1 in the Schwann cell membrane.
Protein: RS12_ACIBT
Sequence: MATTNQLIRKGRTTLVEKSKVPALKACPQRRGVCTRVYTTTPKKPNSAMRKVCRVRLTSGFEVSSYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGSLDCAGVKDRNQSRSKYGAKRPKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: SYP_BURA4
Sequence: MKASRFFIGTLKEAPADAEIVSHKLMVRAGMIRRVAGGIYNYLPVGLRSIRKVEAIVREEMNRAGAIELLMPAVQPAELWQESGRWEQYGPELLRFKDRKDNDFVIGPTHEEVVTDIARNQIKSYRQMPVNFYQIQTKFRDEIRPRFGVMRGREFIMKDAYSFDKDTAGLNESYRKMYDAYVRIFTRLGLEFRAVAADSGSIGGNFSHEFHVIADTGEDAIAYCPTSDFAANIEAAEALPLIAARAAPAEAMEKVATPGKAKCEAVAELLAIPLERTIKSIVLATENEGAEPTIWLIMLRGDHDLNEIKVSKLPGLKNHRFATEQEIVDWFGTPPGYLGPVGTKKPVKVIADRTVANMSDFVVGANEVDYHIAGVNWGRDLPEPEVADVRDVKKGDPSPDGKGTIDICRGIEVGHVFQLGTKYSEAMGATFLDESGKPQPMLMGCYGVGVTRILGAAIEQNFDDRGIIWPESIAPFEVVLCPMGYDRSDMVREAADKLYAELAAAGIDVILDDRGERPGVMFADWELIGVPHRLVIGERGLKEGKIEYQGRRDAEATLLPADEAAATVTEKIRAALAH
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETN_ZYGCR
Sequence: MDIVSIGWAALMVVFTFSLSLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single- pass membrane protein.
Protein: THII_ALIF1
Sequence: MKFIVKPHPEVFVKSDSVRKRFIRILESNLRSIIQRETKGVEVINRRDHIEVTGLSDEYRDVTLAVLTQTPGIHHVLEVKQSGFKDMHDIFEQCLEMNREVIEGKTFCVRVKRRGNHDFTSIELERYVGGGLNQSVESASVRLKNPEVTVKFEVANDKLNLIIARHKGLGGFPLGTQEDVLSLISGGFDSGVSSYLHIKRGSKVHYLFFNLGGPAHEIGVKQVSHFLWKKYGSSAKVKFISVDFDPVVAEILEKVDDGQMGVILKRMFMRAGGMVAEKFGIEGLVTGEALGQVSSQTLTNLRHIDNVTDSLILRPLINWDKEDIIDLAREIGTEDFAKTMPEYCGVISKKPTVKAVKEKLEKEEAKFDFSVLEQAVYNARVMDIRDIEKESQEQAPEVEMVSELGSDVVVLDIRSAEEEDEKPLELDGVEVTHIPFFKLATKFGDLDQSKEYLLYCERGVMSRLQALLLIENGYKNVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_BUCCC
Sequence: MIETIHVNLNNYSYNIYIGEYIFNNMFISSIFLKNKNNVLITNKKIEKKILKNKNQYFYKILNKIHYFSINDGENYKNLYEVEKIISFLLNNLYGRDLNLIALGGGVIGDITGFVASIFQRGVNFFQIPTTLLSQVDASIGGKTGVNHILGKNMIGSFWQPKGVFIDIKFLSTLPKKELLSGIAEIIKYAIVFDKIFFIWLENNLFKVLNLQKKELLYCIKKCCELKVKIIENDEKEIGNRVFLNLGHSFAHAIETFTGYGKWLHGNAVSVGIIMSSYLSFYLKYLKKSELLNIINIFNNIGLPIIGPSTMLPLDYLKLMMRDKKVINKNLRLVIPVSIGKVKLISSIKENILLDSITACQERRFFS
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_SHEPC
Sequence: MEVLAKHRFARTSAQKARLVADQIRGLPVAKALEILTFSPKKAAVLVKKVLDSAIANAEHNEGADIDELKVGAVFVDEGPTMKRIMPRAKGRADRIMKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: SCO22_RICPR
Sequence: MKMQSNITKIIIIMSLLIGVGALYVLLSLSTPKKPLAGQFNIYEDKIKIGGPFELIDQNGEIFNSDKLRGHLSLIYFGFTSCPDICPTSLNKITNIVEILHQNKIDIIPVFITVDPKRDTPEVLKEYIKNFHPKFISLTGNEHQIKDVTDKFKVFYARVNSDNDDQNYMIDHSSFTYLIDKNGRYMKHFYLDISAKEIMELFKNE
What are the official names of this protein?
SCO2-like protein RP587.
What is the protein family that this protein belongs to?
Belongs to the SCO1/2 family.
Protein: UGPA_SALTY
Sequence: MSSSRPVFRSRWLPYLLVAPQLVITVIFFIWPAGEALWYSLQSVDPFGFSSQFVGLENFVALFHDSYYLDAFWTTIKFSALVTFSGLLVSLFFAALVDYVVRGSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLGEFGYDWNHAQNSGQAMFLVVFASVWKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPIRRFFRLSLPLIAPVSFFLLVVNLVYAFFDTFPVIDAATAGGPVQATTTLIYKIYREGFTGLDLSASAAQSVVLMFLVIILTVVQFRYVESKVRYQ
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
sn-glycerol-3-phosphate transport system permease protein UgpA.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. UgpAE subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS5_HALH5
Sequence: MLGIIDYGMGNLHSVSKALERLSWSYIVSEQPEELQKADGLILPGVGSFHDAMSILNETGLTAFIKDWVDEGKPLLGICLGMQLLFEESEENKRTKGLSLLPGRVIRFPGVATDGSTYKVPHMGWNQLTFRKPNHPLLTDVEEGHVYFVHSYVVKTDADDVLLATSHYYETVPAVVGRGNILGTQFHPEKSSNVGMSILRNYGAMVEKGVKARG
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
Protein: OBP_LYMDI
Sequence: TAEVMSHVXAHFGKALEE
What is the function of this protein?
Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid.
What are the official names of this protein?
General odorant-binding protein, GOBP.
What is the protein family that this protein belongs to?
Belongs to the PBP/GOBP family.
Protein: RLMH_LIMRJ
Sequence: MNIKIIGVGKLKEKYFKAGIAEYAKRLGRYCKFEIVEVPDEKAPESLSQAEMDEVMAKEGERILDKIKDREYVYALAIKGKERSSEEFAKEINKLTTYGHSDITFVIGGSLGLSPAVLKRADAQISFGRFTLPHQLMRLVLSEQIYRAFTIINGLPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.