PharMolix/UniProtQA huggingface dataset:
Protein: RL1_CHRVO
Sequence: MAKISKRLQNLKATVDRNKLYAVDEAIALVKAAATAKFDESIDIAVNLGVDPRKSDQVVRGSVVLPRGTGKSVRVAVFAQGANAEAAKAAGAEVVGFDDLAEQVKAGNLDFDVVIASPDAMRVVGQLGQILGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVQYRTDKAGIIHATIGRASFEAEALRENFSALVDALVKAKPAASKGVYLKKIAVSSTMGIGARVDTATVNA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: ERGI3_MOUSE
Sequence: MEALGKLKQFDAYPKTLEDFRVKTCGGATVTIVSGLLMLLLFLSELQYYLTTEVHPELYVDKSRGDKLKINIDVLFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKKRLDKDGVPVSSEAERHELGKVEVTVFDPNSLDPNRCESCYGAESEDIKCCNSCEDVREAYRRRGWAFKNPDTIEQCRREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVHDLQSFGLDNINMTHYIKHLSFGEDYPGIVNPLDHTNVTAPQASMMFQYFVKVVPTVYMKVDGEVLRTNQFSVTRHEKVANGLLGDQGLPGVFVLYELSPMMVKLTEKHRSFTHFLTGVCAIIGGMFTVAGLIDSLIYHSARAIQKKIDLGKTT
What is the function of this protein?
Possible role in transport between endoplasmic reticulum and Golgi.  Positively regulates trafficking of the secretory proteins alpha1-antitrypsin/SERPINA1 and HP/haptoglobin (By similarity).
What are the official names of this protein?
Endoplasmic reticulum-Golgi intermediate compartment protein 3, Serologically defined breast cancer antigen NY-BR-84 homolog.
What is the protein family that this protein belongs to?
Belongs to the ERGIC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Cycles between the endoplasmic reticulum and the Golgi.
Protein: Y2640_BACAN
Sequence: MNRLSTKLVVAIGIGSALYGILGLWGFSIAPNTFIKPALAILTVFGALFGPVAGLLIGLIGHTVTDTIAGWSIWWGWVISSGIIGFTMGFIQKRVGFSVKNGTYNKGDISYLAITGLIGIVIAIIFAGAFDIIVMGEPFDKIVIQVLGATIADVIVFLVLGLPITIGLAKSNKKHTHLKIEK
What are the official names of this protein?
UPF0397 protein BA_2640/GBAA_2640/BAS2460.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1994_ROSDO
Sequence: MQIIWLGHGSFRIEIGDQVLLIDPWLTGNPMLAEDQHAAATTGATHILITHGHFDHTADVVALSKSLEAPVVGIYDFMSYFEAKEGLSVVGFNMGGTVTLGDVAVSLVPALHSTSYGPDATAPLGREAGFIIKGERYTVYVSGDTGISAEMDWIGDYYKPDIGILSAGGHFTMDMKGAAYAAKRYFDFKTVIPCHYKTFDLLEQSATDLIDALPDVDVIEPQVMTPIRF
What are the official names of this protein?
UPF0173 metal-dependent hydrolase RD1_1994.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: PCNB_ECOLI
Sequence: MFTRVANFCRKVLSREESEAEQAVARPQVTVIPREQHAISRKDISENALKVMYRLNKAGYEAWLVGGGVRDLLLGKKPKDFDVTTNATPEQVRKLFRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEGNVSDRTTSQRGQNGMLLRDNIFGSIEEDAQRRDFTINSLYYSVADFTVRDYVGGMKDLKDGVIRLIGNPETRYREDPVRMLRAVRFAAKLGMRISPETAEPIPRLATLLNDIPPARLFEESLKLLQAGYGYETYKLLCEYHLFQPLFPTITRYFTENGDSPMERIIEQVLKNTDTRIHNDMRVNPAFLFAAMFWYPLLETAQKIAQESGLTYHDAFALAMNDVLDEACRSLAIPKRLTTLTRDIWQLQLRMSRRQGKRAWKLLEHPKFRAAYDLLALRAEVERNAELQRLVKWWGEFQVSAPPDQKGMLNELDEEPSPRRRTRRPRKRAPRREGTA
What is the function of this protein?
Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay.  Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.  Rho-independent transcription terminators may serve as polyadenylation signals.  Seems to be involved in plasmid copy number control.
What are the official names of this protein?
Poly(A) polymerase I, PAP I, Plasmid copy number protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane.
Protein: UREF_STAAR
Sequence: MIDHTHLRLFQFCDSQFPTGAFSHSFGLETYIQRNIIHDDHTFIAWLKMFLQEQLTYSDGLAMRLVYDALENDDTQKVLHIDKLMFVQNLPKETRVGAKQMGTRMVKLALELYNNPWIAWYHQQMQDKKAKLNPAICFTMLGHYLGVDIETIIDYYLYQNVSSLTQNAVRAIPLGQTAGQKIVTHMIPYIEETRKQIFELKEADFGMTAPGLELNQMAHENVNVRIFIS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_STRT2
Sequence: MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLVEENQVTLKEERVLEWLSKGAQPSDTVRNILSKEGVMKKFHESKFSK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: LPXB_VIBVU
Sequence: MSNKPLRIGIVAGELSGDTLGEGFIKAIKAVHPDAEFVGIGGPKMIALGCQSLFDMEELAVMGLVEVLGRLPRLLKVKAELVRYFTENPPDVFVGIDAPDFNLRLELDLKNAGIKTVHYVSPSVWAWRQKRIFKIAKATHLVLAFLPFEKAFYDKFNVPCEFIGHTLADAIPLESDKAPARELLGLEQDKQWLAVLPGSRGSELKMLSQPFIETCKKLQQAFPELGFVVALVNQKRREQFEQAWKEYAPELDFKLVDDTARNVITASDAVMLASGTVALECMLLKRPMVVGYRVNAVTAFLAKRLLKTQYVSLPNILADTELVKEYLQDDCTPDNLFGEVSRLLEGDNHQMLDKFTEMHHWIRKDADQQAANAVLKLIEK
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: RL15_CLOBK
Sequence: MKLHELRAAEGANKASKRVGRGTGSGLGKTSGRGQNGQNSRSGGGVRPGFEGGQMPLYRRLPKRGFKNIFAKEYAAINLDRLNCFEDGTVVTPELLVEKRVVKKVKDGVKILGNGNIEKKLTVKAAKFSKSAIEKIEAAGGKVEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: IGDC3_HUMAN
Sequence: MAVQRAASPRRPPAPLWPRLLLPLLLLLLPAPSEGLGHSAELAFAVEPSDDVAVPGQPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGSLMIRHFRLEPGGSPSDEGDYECVAQNRFGLVVSRKARIQAATMSDFHVHPQATVGEEGGVARFQCQIHGLPKPLITWEKNRVPIDTDNERYTLLPKGVLQITGLRAEDGGIFHCVASNIASIRISHGARLTVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRLDGRPIGVEGIQVLGTGNLIISDVTVQHSGVYVCAANRPGTRVRRTAQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLGPGGHVRLKNNNSTLTISGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEGLPGPPRNVRAVSVSSTEVRVSWSEPLANTKEIIGYVLHIRKAADPPELEYQEAVSKSTFQHLVSDLEPSTAYSFYIKAYTPRGASSASVPTLASTLGEAPAPPPLSVRVLGSSSLQLLWEPWPRLAQHEGGFKLFYRPASKTSFTGPILLPGTVSSYNLSQLDPTAVYEVKLLAYNQHGDGNATVRFVSLRGASERTALSPPCDCRKEEAANQTSTTGIVIGIHIGVTCIIFCVLFLLFGQRGRVLLCKDVENQLSPPQGPRSQRDPGILALNGARRGQRGQLGRDEKRVDMKELEQLFPPASAAGQPDPRPTQDPAAPAPCEETQLSVLPLQGCGLMEGKTTEAKTTEATAPCAGLAAAPPPPDGGPGLLSEGQASRPAAARVTQPAHSEQ
What are the official names of this protein?
Immunoglobulin superfamily DCC subclass member 3, Putative neuronal cell adhesion molecule.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. DCC family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL3_XANOP
Sequence: MTKKYSLGFVGRKAGMSRIFTEDGRSVPVTLIEATPNRIAQIKTVEVDGYSAVQITVGARRAALVNKPAAGHFAKAKVEAGRGLWEFRVEDAHLGDFAVGGEIKADIFEVGQKVDVQGVTKGKGFQGTIKRYNFRMGDATHGNSLSHRAPGSLGQRQTPGRVFPGKKMSGHMGAVQQSTQNLEVVKVDVERGLIAIHGAVPGAAGGDVIVRPASKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: UBACT_HANXR
Sequence: MSGRSTFGRFGPPSSEPWERKPGDDEGGPKRPKVERPDTNDLLKRMRRVDPNQSRRYRQRTGE
What is the function of this protein?
May function as a protein modifier covalently attached to lysine residues of substrate proteins.  This may serve to target the modified proteins for degradation by proteasomes.
What are the official names of this protein?
Prokaryotic ubiquitin-like protein UBact.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-like protein UBact family.
Protein: DRE1A_ORYSI
Sequence: MCGIKQEMSGESSGSPCSSASAERQHQTVWTAPPKRPAGRTKFRETRHPVFRGVRRRGNAGRWVCEVRVPGRRGCRLWLGTFDTAEGAARAHDAAMLAINAGGGGGGGACCLNFADSAWLLAVPRSYRTLADVRHAVAEAVEDFFRRRLADDALSATSSSSTTPSTPRTDDEEESAATDGDESSSPASDLAFELDVLSDMGWDLYYASLAQGMLMEPPSAALGDDGDAILADVPLWSY
What is the function of this protein?
Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'.  Binding to the C-repeat/DRE element mediates high salinity- and dehydration-inducible transcription.  Confers resistance to high salt, cold and drought stress (By similarity).
What are the official names of this protein?
Dehydration-responsive element-binding protein 1A, Protein DREB1A, Protein C-repeat-binding factor 3, rCBF3.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ZN671_HUMAN
Sequence: MLSPVSRDASDALQGRKCLRPRSRRLPLPAAVRAHGPMAELTDSARGCVVFEDVFVYFSREEWELLDDAQRLLYHDVMLENFALLASLGIAFSRSRAVMKLERGEEPWVYDQVDMTSATEREAQRGLRPGCWHGVEDEEVSSEQSIFVAGVSEVRTLMAELESHPCDICGPILKDTLHLAKYHGGKARQKPYLCGACGKQFWFSTDFDQHQNQPNGGKLFPRKEGRDSVKSCRVHVPEKTLTCGKGRRDFSATSGLLQHQASLSSMKPHKSTKLVSGFLMGQRYHRCGECGKAFTRKDTLARHQRIHTGERPYECNECGKFFSQSYDLFKHQTVHTGERPYECSECGKFFRQISGLIEHRRVHTGERLYQCGKCGKFFSSKSNLIRHQEVHTGARPYVCSECGKEFSRKHTLVLHQRTHTGERPYECSECGKAFSQSSHLNVHWRIHSSDYECSRCGKAFSCISKLIQHQKVHSGEKPYECSKCGKAFTQRPNLIRHWKVHTGERPYVCSECGREFIRKQTLVLHQRVHAGEKL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 671.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPE_PROM9
Sequence: MPISLKVLAPNKNVYQGEAEEVILPSTTGQLGVLPGHISLVTAIDIGVLRLRMNSQWQSIALMGGFAEIESDEVIVLVNNAEIGSDIDVQNAEQDLKEAKLVMTKFPENEKNSEKIKALQEISKAEARIQAAKN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: ISCS_RICRS
Sequence: MTPQLNNLTLPIYMDYQATTPIDPRVMEAMLPYFTTKFGNPHSRSHSFGWEAENAVEEARSMVAKLIGADTKEIIFTSGATESNNLAIKGIAKFYSNKKNHIITVVSEHKCVLDACRHLEQEGIKITYLPIKPNGIIDLETLKNAITDQTMLVSVMVVNNEIGVVQPLKEIGKICREKGVFFHSDIAQGFGKIPIDVNAFNIDLASISGHKIYGPKGIGALYVRKKPRVRITPLINGGGQERGMRSGTLPTPLIVGLGMAAEIAYSEMEKDTKHVNYLFDRFLNNIHKRISEVYLNGDKNQRYKGNLNLSFAGVEGESMILAIKDLAVSSGSACTSASLEPSYVLRSIGIGEELAHTAIRFGIGRFTTEQEVDYAVNLICSKIDKLRALSPLWEMMQEGIDLKKIKWAVH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HB2I_MOUSE
Sequence: MVWLPRVPCVAAVILLLTVLSPPVALVRDSRPWFLEYCKSECHFYNGTQRVRFLKRYFYNLEENLRFDSDVGEFRAVTELGRPDAENWNSQPEILDEKRAAVDTYCRHNYEIFDNFLVPRRVEPTVTVYPTKTQPLEHHNLLVCSVSDFYPGNIEVRWFRNGKEEKTGIVSTGLVRNGDWTFQTLVMLETVPQSGEVYTCQVEHPSLTDPVTVEWKAQSTSAQNKMLSGVGGFVLGLLFLRAGLFIYFRNQKGQSGLQPTGLLS
What are the official names of this protein?
H-2 class II histocompatibility antigen, I-A beta chain.
What is the protein family that this protein belongs to?
Belongs to the MHC class II family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CDS1_HUMAN
Sequence: MLELRHRGSCPGPREAVSPPHREGEAAGGDHETESTSDKETDIDDRYGDLDSRTDSDIPEIPPSSDRTPEILKKALSGLSSRWKNWWIRGILTLTMISLFFLIIYMGSFMLMLLVLGIQVKCFHEIITIGYRVYHSYDLPWFRTLSWYFLLCVNYFFYGETVADYFATFVQREEQLQFLIRYHRFISFALYLAGFCMFVLSLVKKHYRLQFYMFAWTHVTLLITVTQSHLVIQNLFEGMIWFLVPISSVICNDITAYLFGFFFGRTPLIKLSPKKTWEGFIGGFFSTVVFGFIAAYVLSKYQYFVCPVEYRSDVNSFVTECEPSELFQLQTYSLPPFLKAVLRQERVSLYPFQIHSIALSTFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVHVYITSFIRGPNPSKVLQQLLVLQPEQQLNIYKTLKTHLIEKGILQPTLKV
What is the function of this protein?
Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol (PubMed:9407135, PubMed:25375833).  Exhibits almost no acyl chain preference for PA, showing no discrimination for the sn-1/sn-2 acyl chain composition of PAs (PubMed:25375833).  Plays an important role in regulating the growth of lipid droplets which are storage organelles at the center of lipid and energy homeostasis (PubMed:26946540, PubMed:31548309).  Positively regulates the differentiation and development of adipocytes (By similarity).
What are the official names of this protein?
Phosphatidate cytidylyltransferase 1, CDP-DAG synthase 1, CDP-DG synthase 1, CDP-diacylglycerol synthase 1, CDS 1, CDP-diglyceride pyrophosphorylase 1, CDP-diglyceride synthase 1, CTP:phosphatidate cytidylyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the CDS family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SC22C_HUMAN
Sequence: MSVIFFACVVRVRDGLPLSASTDFYHTQDFLEWRRRLKSLALRLAQYPGRGSAEGCDFSIHFSSFGDVACMAICSCQCPAAMAFCFLETLWWEFTASYDTTCIGLASRPYAFLEFDSIIQKVKWHFNYVSSSQMECSLEKIQEELKLQPPAVLTLEDTDVANGVMNGHTPMHLEPAPNFRMEPVTALGILSLILNIMCAALNLIRGVHLAEHSLQVAHEEIGNILAFLVPFVACIFQCYLYLFYSPARTMKVVLMLLFICLGNMYLHGLRNLWQILFHIGVAFLSSYQILTRQLQEKQSDCGV
What is the function of this protein?
May be involved in vesicle transport between the ER and the Golgi complex.
What are the official names of this protein?
Vesicle-trafficking protein SEC22c, SEC22 vesicle-trafficking protein homolog C, SEC22 vesicle-trafficking protein-like 3.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SQSTM_PONAB
Sequence: MASLTVKAYLLGKEDAAREIRRFSFCCSPEPEAEAEAAAGPGPCERLLSRVAALFPALRPGGFQAHYRDEDGDLVAFSSDEELTMAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWSGWEMGPPGNWSPRPPRAGEARPGPTAESASGPSEDPSVNLLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGRLTRLLQTKNYDIGAALDTIQYSKHPPPL
What is the function of this protein?
Autophagy receptor required for selective macroautophagy (aggrephagy).  Functions as a bridge between polyubiquitinated cargo and autophagosomes.  Interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family.  Along with WDFY3, involved in the formation and autophagic degradation of cytoplasmic ubiquitin-containing inclusions (p62 bodies, ALIS/aggresome-like induced structures).  Along with WDFY3, required to recruit ubiquitinated proteins to PML bodies in the nucleus.  Also involved in autophagy of peroxisomes (pexophagy) in response to reactive oxygen species (ROS) by acting as a bridge between ubiquitinated PEX5 receptor and autophagosomes (By similarity).  May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1.  May play a role in titin/TTN downstream signaling in muscle cells.  May regulate signaling cascades through ubiquitination.  Adapter that mediates the interaction between TRAF6 and CYLD (By similarity).  May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels.  Involved in endosome organization by retaining vesicles in the perinuclear cloud: following ubiquitination by RNF26, attracts specific vesicle-associated adapters, forming a molecular bridge that restrains cognate vesicles in the perinuclear region and organizes the endosomal pathway for efficient cargo transport.  Promotes relocalization of 'Lys-63'-linked ubiquitinated STING1 to autophagosomes.  Acts as an activator of the NFE2L2/NRF2 pathway via interaction with KEAP1: interaction inactivates the BCR(KEAP1) complex, promoting nuclear accumulation of NFE2L2/NRF2 and subsequent expression of cytoprotective genes (By similarity).  Sequesters tensin TNS2 into cytoplasmic puncta, promoting TNS2 ubiquitination and proteasomal degradation (By similarity).
What are the official names of this protein?
Sequestosome-1, Ubiquitin-binding protein p62.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Late endosome. Nucleus. Endoplasmic reticulum. Lysosome. Cytoplasmic vesicle, autophagosome. Nucleus, PML body. Cytoplasm, myofibril, sarcomere. Note=In cardiac muscles, localizes to the sarcomeric band. Localizes to late endosomes. May also localize to the hepatocellular carcinoma. Colocalizes with TRIM13 in the perinuclear endoplasmic reticulum (By similarity). Co-localizes with TRIM5 in cytoplasmic bodies (By similarity). When nuclear export is blocked by treatment with leptomycin B, accumulates in PML bodies (By similarity).
Protein: YIAJ_ECOLI
Sequence: MGKEVMGKKENEMAQEKERPAGSQSLFRGLMLIEILSNYPNGCPLAHLSELAGLNKSTVHRLLQGLQSCGYVTTAPAAGSYRLTTKFIAVGQKALSSLNIIHIAAPHLEALNIATGETINFSSREDDHAILIYKLEPTTGMLRTRAYIGQHMPLYCSAMGKIYMAFGHPDYVKSYWESHQHEIQPLTRNTITELPAMFDELAHIRESGAAMDREENELGVSCIAVPVFDIHGRVPYAVSISLSTSRLKQVGEKNLLKPLRETAQAISNELGFTVRDDLGAIT
What is the function of this protein?
Negatively controls the transcription of the yiaKLMNOPQRS operon, which may be involved in the utilization of 2,3-diketo-L-gulonate.
What are the official names of this protein?
DNA-binding transcriptional repressor YiaJ, YiaKLMNOPQRS operon repressor, YiaK-S operon repressor.
Protein: RL20_RENSM
Sequence: MARVKRAVNAHKKRRVILERAKGYRGQRSRLYRKAKEQLLHSFVYSYGDRRKRKGDFRRLWIQRINAASRANGLTYNRLIQGLKAASIEVDRRMLSELAVNDAAAFAGLVKLAKAALPADTSAPVAN
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: NOP10_DEBHA
Sequence: MHLMYTLGPDGKRVYTLNKTTSDGEITKSAHPARFSPDDKYSRQRVTLKKRFGLLPTQ
What is the function of this protein?
Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis.  This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1.  Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.  The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs.  The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA.
What are the official names of this protein?
H/ACA ribonucleoprotein complex subunit NOP10, Nucleolar protein 10, Nucleolar protein family A member 3, snoRNP protein NOP10.
What is the protein family that this protein belongs to?
Belongs to the NOP10 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: YIPF3_CHICK
Sequence: MSAPGGGRSGPAEWGGFEDNMQGGGSAVIDMENMDDTSGSSFEDMGEMHQRMKEEEEEEAEGEAGAGGEEDGEFLGMKGLQGQLGRQVADQMWQVGKRQASKAFSLYANIDILRPYFDVEPVQVRTRLLESMVPVKMINFPQKIAGELYGPLMLVFTLVAILLHGMKTSDTIIREGTLMGTAIGTCFGYWLGVSSFIYFLAYLCNAQITMVQMLSLLGYGLFGHCITLLVTYNIHFHSLFYIFWLVVGGLSTLRMVAVLVSRTVGHTQRLILCGTLAALHMLFLLYLHFAYHKVVEGILDTLEGPNMPPFQRVARDIPVVSNAVLNTTAKANAMTL
What is the function of this protein?
Involved in the maintenance of the Golgi structure.  May play a role in hematopoiesis (By similarity).
What are the official names of this protein?
Protein YIPF3, YIP1 family member 3.
What is the protein family that this protein belongs to?
Belongs to the YIP1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Cytoplasm.
Protein: SPL5_ARATH
Sequence: MEGQRTQRRGYLKDKATVSNLVEEEMENGMDGEEEDGGDEDKRKKVMERVRGPSTDRVPSRLCQVDRCTVNLTEAKQYYRRHRVCEVHAKASAATVAGVRQRFCQQCSRFHELPEFDEAKRSCRRRLAGHNERRRKISGDSFGEGSGRRGFSGQLIQTQERNRVDRKLPMTNSSFKRPQIR
What is the function of this protein?
Trans-acting factor that binds specifically to the consensus nucleotide sequence 5'-TNCGTACAA-3' of AP1 promoter.  Promotes both vegetative phase change and flowering.
What are the official names of this protein?
Squamosa promoter-binding-like protein 5.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Mostly located in nucleus.
Protein: NA123_ACTEQ
Sequence: MNRLMILVFAAVILALASADEDVDITKRGVPCLCVSDGPRPRGNNLSGIMWMKTGGYGGNGCPKGWHFCGKSRGFFSDCCKR
What is the function of this protein?
Binds specifically to voltage-gated sodium channels (Nav), thereby delaying their inactivation during signal transduction.  Causes death to crabs.
What are the official names of this protein?
Delta-actitoxin-Aeq2b 3, Delta-AITX-Aeq2b 3, Ae2-3, Neurotoxin 2-3.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type I subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: CHED_CLOB1
Sequence: MDIKEIKVGIADLNVGKNPDKIITVGLGSCIGIALYDGIKCIGGLSHIMLPDSTQFSKVTNPMKFADLAIPILVEKMEKLGARKNGLKAKICGGASMFNFSDKSMVMDIGNRNGKAVKEKLKELSIPLLAEDIGGNKGRTMIFDTSTGKVYIKTVGLGTKEI
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: AROA_STAAE
Sequence: MVNEQIIDISGPLKGEIEVPGDKSMTHRAIMLASLAEGVSTIYKPLLGEDCRRTMDIFRLLGVEIKEDDEKLVVTSPGYQSFNTPHQVLYTGNSGTTTRLLAGLLSGLGIESVLSGDVSIGKRPMDRVLRPLKLMDANIEGIEDNYTPLIIKPSVIKGINYQMEVASAQVKSAILFASLFSKEPTIIKELDVSRNHTETMFKHFNIPIEAEGLSINTTPEAIRYIKPADFHVPGDISSAAFFIVAALITPGSDVTIHNVGINPTRSGIIDIVEKMGGNIQLFNQTTGAEPTASIRIQYTPMLQPITIEGELVPKAIDELPVIALLCTQAVGTSTIKDAEELKVKETNRIDTTADMLNLLGFELQPTNDGLIIHPSEFKTNATVDSLTDHRIGMMLAVASLLSSEPVKIKQFDAVNVSFPGFLPKLKLLENEG
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.