PharMolix/UniProtQA huggingface dataset:
Protein: FEZF2_BOVIN
Sequence: MASSASLETMVPPACPRAGASPATSKTLAFSIERIMAKTSEPRAPFEPRPGALEADSGQGKKLLNLCSPLPCMIPLQPLGYEMPSKTLLSYSELWKSSLRAGGSGGGGGGGGGGGGAPVCGASGLCKTNCGVCCKAELGLVPSALPAGRVIKPQVINQAVGLPASGSLYYFNYLDSATYPSSELLGGHLFPSGLLNTQAPAALAAHPKLFLLENAKLAGLTADKFAHPAPYAHKERLPAPLEQVLKENSALTAERGGVKGHSKLPGGSADGKPKNFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHIRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQYKCTICNKAFHQVYNLTFHMHTHNDKKPFTCATCGKGFCRNFDLKKHVRKLHDSVGPAAPSTKDLTRTVQS
What is the function of this protein?
Transcription repressor.  Binds to 5'GCAG-3' core sequence.  Required for the specification of corticospinal motor neurons and other subcerebral projection neurons.  May play a role in layer and neuronal subtype-specific patterning of subcortical projections and axonal fasciculation.  Controls the development of dendritic arborization and spines of large layer V pyramidal neurons (By similarity).  May be responsible for mastitis resistance and innate immunity.
What are the official names of this protein?
Fez family zinc finger protein 2, Forebrain embryonic zinc finger-like protein 2, Zinc finger protein 312, Zinc finger protein Fez-like.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
Protein: OBG_MYCLB
Sequence: MPRFVDRVVIHTWAGSGGNGCASIHRSKFKPLGGPDGGNGGRGGSVVFVVDPHVHTLLDFHFRPHITAPSGKQGMGNNRDGAAGADLEVKVPDGTVVLDEDGRLLADLVGAGTRFQAAAGGRGGLGNAALASRTRKVPGFALLGEQGESRDLTLELKSVADVGLIGFPSAGKSSLVSVISAAKPKIADYPFTTLVPNLGVVSVGEHAFTVADVPGLIPGASAGRGLGLDFLRHIERCAVLVHVVDCTSVEPGRDPILDIAALEAELAAYTPTLQGDTTLGDFAERPRAVVLNKIDVPDARELAEFVCDNIAAERGWPVFSVSTVTRENLQSLIFGLWQMISAYHAARSEPAPGRSLIRPVPVDDSGFTVEPDGQGGFVVTGTRPERWIHQTNFDNAEAVGYLADRLARLGVEDELLRVGAQPGCTVSIGGMTFDWEPQKPAGHPVAMSGRGTDARLESTDPVGTAERKVARHQRHKHGG
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL004_HUMAN
Sequence: MSPTTGPQPNPRAWECHHTTGPQPNPRAWECHRMKGPQPNPRAWECHLRRVHNLTPEPGNVTIRGVHILTPEPGNVTIRGVHNLTPEPGNVTERGVHNLTPEPGNVTERGVHNLIPEPGNVTVKRGPQPNPRAWECHRTRGPQPNPRAWECHRTRGPQPNPRAWECHR
What are the official names of this protein?
Putative uncharacterized protein FLJ45999.
Protein: DPOL_PSHV1
Sequence: MAAFDNPVFNKTLTPVAGAGPNFRATYYTSVTEFTHVCPRSLIDGERLGTSVGKVADPPRFTVDDRTVDMFSHDHGAWPMRMEHWPGTSAERRRDKNALRFHEFHVYDIIEAHETAQSCSAWLHPRFMETLRPSGTVVTLLGMSACGKRVAVHVYGQQPYFYAKKSEIDASIGISTPGELAHAMAASLRSAASRRSTFVEATAESFVIDVVQRRDIYYYESREEEYYRVKSCSAKYISFLCDNFCRGVKKYEGGIDATTRFAVDNELFTFGWYRFKPCAGAIQIRDVTRHSTSANVEVNCTVENLEVIRGRADWPDYKLLSFDIECKAGGANDLAFPTAERIEDVVIQISAVVSSLLTRRVEHEILFSLGTCQLPEDIADHVKVCECGSEFELLLCFMTFLKQFSPEFVTGYNILGFDWGFMYNKMVNIYGMRLDGYGKANAWGTFKVQDMPHSGRGKFRNVKINGIVNFDMFSIIYQKIKLCSYKLNSVAETVLGEKKHDLSYKDLPRLFALGPEERGKIGAYCLQDSRLATKLFFKLVPHMELSAVAQLACITLTRAVFDGQQVRVFTCLLQRARKIGVVLPEKSDRFTFSAHAAGDQDDGGRSVGYQGAKVLDPDVGFHVNPVMVFDFASLYPSIIQSNNLCYSTMTHNPAAIAHLEEGTDYLRVEVQGRVFFFVREHVRRSLLAELLTDWLNMRKALRAQIPLAATEDEKVLLDMQQIAIKVICNSVYGFTGVMNGMLPCLEVAATVTAIGRDMLLKTKQYIEENWREYSNIRERFFPAMAHEGVPQYSVAVIYGDTDSVFVSFKGVPVACLVASGDAMAAEITNALFRRPVKLECEKVFTKLLMIAKKKYIGVIHTGKMMMRGVDMVRKSNCRFVNDTAKALLNLVFYDEDVATAAASSALVDVSALPRGLSKLGARVREAHAALSSPALDVRDFVMTSELSKAPKYYASSKLAHLTVYRKKIARNEEPPQVKDRIEYVIIAPGQRIQGDPFREKETDLVSSLAEDPNWVTAHKLRLNADYYFSALLQTLSVTFNAVFGDAKTAHIVMRSFIPDTLRYPAAVRKILAENTKTLTPM
What is the function of this protein?
Replicates viral genomic DNA.  The replication complex is composed of six viral proteins: the DNA polymerase, processivity factor, primase, primase-associated factor, helicase, and ssDNA-binding protein.  Additionally, the polymerase contains an intrinsic ribonuclease H (RNase H) activity that specifically degrades RNA/DNA heteroduplexes or duplex DNA substrates in the 5' to 3' direction.  Therefore, it can catalyze the excision of the RNA primers that initiate the synthesis of Okazaki fragments at a replication fork during viral DNA replication (By similarity).
What are the official names of this protein?
DNA polymerase catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Host nucleus. Note=The protein is present at discrete sites in nuclei, called replication compartments where viral DNA replication occurs.
Protein: ASNA_CULQU
Sequence: MEADFEPLEPSLRNIIDQKSLKWIFVGGKGGVGKTTCSCSLAVQLAKDRESVLIISTDPAHNISDAFDQKFTKVPSKVNGFDNLFAMEIDPNVGLNELPDEYFEGENSAMKLSKGVFQEIIGALPGIDEAMSYAEVMKLVKAMNFSTVVFDTAPTGHTLRLLSFPQVVEKGLGKLLRLKMKLAPFISQMGSLFGMQDFNADTLTGKLEEMLTIIRQVNEQFRNPDQTTFVCVCIAEFLSLYETERLVQELTKCGIDTHNIIVNQLLFRREGQAPCAMCSARYKVQGKYLDQIADLYEDFHVVKLPLLDKEVRGAEKVKKFSVNLIEPYSPEKAAAEAVAEEEEEGTSK
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
What are the official names of this protein?
ATPase ASNA1 homolog, Arsenical pump-driving ATPase homolog, Arsenite-stimulated ATPase.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: DCUP_DROVI
Sequence: MTIKNNNNNNTLKHLQAFPPLKNDNLLRAARGEVVDRVPVWVMRQAGRYLPEFQELRKQHDFFTVCRTPELACEVTMQPLRRFDLDASIIFSDILVIPQALGLTVEMHAGVGPVLPQPICTPEDLKRLTPDGALSRLTYVGDAITMMRHKLDGRVPLIGFTGAPWTLMGYMIEGGGSKTMSKAKAWLTNYPEDTKLFLILLTDVIVDYLEMQVIAGAQMLQVFESSAEHLSKEEFLLGSEPYLRRIRDDLVDRLTKKVIPAVPLVSSYPNNIFTLLTYLISLLIIFAKGAGHSLKEQSELGYDVIGLDWTVDPVEARAVVGPNITLQGNLDPQSMYCEPNELRSLATEMVHKCGKSRYIANVGHGITPQTPITSMEVLVEAAHNAL
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABM_MAGO7
Sequence: MFAVIFETRPQPSQFDTYLTIAKSLRPELANIDGFIENIRYKSLSRPGWILSLSFWRDEKSLVRWRTTATHHMAQEKGRDGVLEDYHLRVGQVTASVRSNEVKRVETVDAREQDDVTAVGAAKTVQLVRFQMDRGAGIDAAAGKLGLNPEEPRGLLAWDIMEAVLSPGDMILLASWETGSSSVSIPGADSDEVQVLRDYGKYDRREAPQFYPPAS
What is the function of this protein?
Monooxygenase that converts the endogenous (and likely the host) jasmonate (JA) to its hydroxylated derivative 12-hydroxyjasmonate (12OH-JA), also known as tuberonic acid, a compound that attenuates or disables jasmonate-based host innate immunity and which is essential for proper initiation and elaboration of the blast disease in rice (PubMed:26258762).  ABM, together with a polyketide synthase MGG_04775 and the esterase MGG_04774, share the secondary metabolism gene cluster with ABC transporter ABC3, and therefore may also be involved in the synthesis of other important metabolites such as the ABC3 transporter efflux substrate (ATS) and/or additional polyketides (Probable).
What are the official names of this protein?
Jasmonate monooxygenase ABM, Antibiotic biosynthesis monooxygenase, ABM.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Secreted. Note=Associates with the cortical endoplasmic reticulum (ER) network during pre-invasive pathogenic development on the host surface pathogenesis and remains associated with the cortical ER in the invasive hyphae untill the later stages of host colonization (PubMed:26258762). Associates also, albeit weakly, with the biotrophic interfacial complex (BIC), a specialized secretory organelle present on the invasive hyphae in M.oryzae (PubMed:26258762). Secreted specifically during invasive growth (PubMed:26258762).
Protein: PSAA_CHAGL
Sequence: MTIRSPETEVKIVVEKDPVKTSFEKWAQPGHFSRTLAKGPSTTTWIWNLHADAHDFDSHTSDLEEISRKVFSAHFGQIAVILIWLSGMYFHGARFSNYEAWLSDPTHIKPSAQVVWPIVGQEILNGDVGGGFQGVQITSGFFQIWRASGITSELQLYSTAIGGLVLATLTLIGGWYHYHKAAPTLAWFQDVESMLNHHLAGLIGLGSLSWAGHQIHVSLPINQLLDAGVDPKEIPLPHEFILNRELLAQLYPSFSKGLTPFFTLNWSEYSDFLTFRGGLNPVTGGLWLSDTAHHHLAIAVLFIIAGHQYRTNWGIGHSLREILEAHKGPFTGEGHKGLYEILTTSWHAQLALNLALFGSLTIIVAHHMYAMPPYPYLATDYGTQLSLFTHHMWIGGFLVTGAAAHAAIFLVRDYDPTTQYNNLLDRVLRHRDAIISHLNWVCIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPVFAQWIQNTHTLAPTLTAPNAASSTSITWGGNLVAVGGKVALLPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNSISVVIFHFSWKMQSDVWGTVTSNGVSNITGGNFAQSANTINGWLRDFLWAQASQVIQSYGSALSAYGLIFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPAIQPRALSIIQGRAVGVAHYLLGGIATTWAFFLARIISVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PTH_XYLFT
Sequence: MLGLRLIVGLGNPGSEYIKTRHNAGFRFVDGLVQREGQCWALESKLFAYVARVFIAGQWVWLLRPVTFMNLSGKSICAGLNFWKIKPEQMLVAHDELDFPPGAVRLKFDGGHGGQNGLRDITKLLGHGRFHRLRVGIGHPGHKDRVVSWVLGCPTCDENIAIDAALERASVVLPLAVAGDFDGAMKKLHTVV
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHO_MICAN
Sequence: MAATIKKGALVRVVTGNLENSLEALASDRRLPSYMFNSTAEVLDVKDDYALIKFYVPTPSVWLKLEQLEPV
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit O, NAD(P)H dehydrogenase I subunit O, NDH-1 subunit O, NDH-O.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhO subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YAAA_ESCF3
Sequence: MLILISPAKTLDYQSPLATTRFTLPELLDHSQQLIHEARKLSAPQIKKLMNISDKLADLNATRFHDWQPNFTLENARQAILAFKGDVYTGLQAETFSEEDFDFAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENAKGKDLYQFWGDVITHKLNEVIDAQGIRFVINLASDEYFKSVKPKKLNAELIKPVFLDEKNGKFKVISFYAKKARGLMSRFIIDNRLTKPEQLKDFNREGYFFDEEASANGELVFKRHEQ
What are the official names of this protein?
UPF0246 protein YaaA.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: GLPK_BACSU
Sequence: METYILSLDQGTTSSRAILFNKEGKIVHSAQKEFTQYFPHPGWVEHNANEIWGSVLAVIASVISESGISASQIAGIGITNQRETTVVWDKDTGSPVYNAIVWQSRQTSGICEELREKGYNDKFREKTGLLIDPYFSGTKVKWILDNVEGAREKAEKGELLFGTIDTWLIWKMSGGKAHVTDYSNASRTLMFNIYDLKWDDELLDILGVPKSMLPEVKPSSHVYAETVDYHFFGKNIPIAGAAGDQQSALFGQACFEEGMGKNTYGTGCFMLMNTGEKAIKSEHGLLTTIAWGIDGKVNYALEGSIFVAGSAIQWLRDGLRMFQDSSLSESYAEKVDSTDGVYVVPAFVGLGTPYWDSDVRGSVFGLTRGTTKEHFIRATLESLAYQTKDVLDAMEADSNISLKTLRVDGGAVKNNFLMQFQGDLLNVPVERPEINETTALGAAYLAGIAVGFWKDRSEIANQWNLDKRFEPELEEEKRNELYKGWQKAVKAAMAFK
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: RAE1D_MOUSE
Sequence: MAKAAVTKRHHFMIQKLLILLSYGYTNGLDDAHSLRCNLTIKAPTPADEVKCFVGEILILHLSNINKTMTSGDPGETANATEVGECLTQPLKDLCQKLRDKVSNTKVDTHKTNGYPHLQVTMIYPQSQGQTPSATWEFNISDSYFFTFYTEIMSWRSANDESGVIMNKWKDDGEFVKQLKFLIHGCSQKMDEFLKQSKEKPRSTSRSPSITQLTSTSPLPPTSHSTSKKGFISVGLIFISLLFAFAFAM
What is the function of this protein?
Acts as a ligand for KLRK1.
What are the official names of this protein?
Retinoic acid early-inducible protein 1-delta, RAE-1-delta.
What is the protein family that this protein belongs to?
Belongs to the NKG2D ligand family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: CNPD3_VESOH
Sequence: MNYSLIQISDCHIDDNKYSMGVNTHINLKKIISRISHINIDVLLITGDLTHKGSITSYKALQQMLYPIQIKLLIIPGNHDNKNNLSATFSKNLFSQFTLGKWEIININSVQVSKTSGFLTKDELIKLELNLAQSIAQYILITLHHPTVPMNSTWDDSLSLENPEALFNVLDKYHKIQAILFGHAHQAAEFKRLGVKIISCPSTALQFNNETRIGFNYYTLYDNGQLTINTQWI
What are the official names of this protein?
Probable cyclic nucleotide phosphodiesterase COSY_0614.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase class-III family.
Protein: DRE2_YEAS2
Sequence: MSQYKTGLLLIHPAVTTTPELVENTKAQAASKKVKFVDQFLINKLNDGSITLENAKYETVHYLTPEAQTDIKFPKKLISVLADSLKPNGSLIGLSDIYKVDALINGFEIINEPDYCWIKMDSSKLNQTVSIPLKKKKTNNTKLQSGSKLPTFKKASSSTSNLPSFKKADHSRQPIVKETDSFKPPSFKMTTEPKVYRVVDDLIEDSDDDDFSSDSSKAQYFDQVDTSDDSIEEEELIDEDGSGKSMITMITCGKSKTKKKKACKDCTCGMKEQEENEINDIRSQQDKVVKFTEDELTEIDFTIDGKKVGGCGSCSLGDAFRCSGCPYLGLPAFKPGQPINLDSISDDL
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35.  Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18.  TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
What are the official names of this protein?
Fe-S cluster assembly protein DRE2, Anamorsin homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: YGFZ_ECOL6
Sequence: MAFTPFPPRQPTASARLPLTLMTLDDWALATITGADSEKYMQGQVTADVSQMTEDQHLLAAHCDAKGKMWSNLRLFRDGDGFAWIERRSVREPQLTELKKYAVFSKVTIAPDDERVLLGVAGFQARAALANLFSELPSREKQVVKEGATTLLWFEHPAERFLIVTDEATANMLTDKLRGEAELNNSQQWLALNIEAGFPVIDAANSGQFIPQATNLQALGGISFKKGCYTGQEMVARAKFRGANKRALWLLKGSASRLPEAGEDLELKMGENWRRTGTVLATVKLEDGQVVVQVVMNNDMEPDSIFRVRDDANTLRIEPLPYSLEE
What is the function of this protein?
Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs.  It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.
What are the official names of this protein?
tRNA-modifying protein YgfZ.
What is the protein family that this protein belongs to?
Belongs to the tRNA-modifying YgfZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_HAHCH
Sequence: MAHKKAAGSSRNGRDSESKRLGVKRFGGQFVKAGNILVRQRGTEFHPGENVGCGRDHTLFAKQDGFVKFNVGGPLNRRTVSIVAAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: DXR_SALPA
Sequence: MKQLTILGSTGSIGCSTLDVVRHNPDSFRVIALVAGKNVARMAEQCLEFSPRYAVMDDTSSAEQLKIMLQQHGSRTEVLSGQQAACEMAALDEVGHVMAAIVGAAGLLPTLAAIRAGKTILLANKESLVTCGRLFMDEVKRSNARLLPVDSEHNAIFQSLPQSIQHNLGYADLEQNGVTSILLTGSGGPFRETPMCDLAAMTPDQACRHPNWSMGRKISVDSATMMNKGLEYIEARWLFNASARQMEVLIHPQSVIHSMVRYQDGSVLAQLGEPDMRTPIAHTMAWPNRVTSGAQPLDFCKLSALTFSAPDYQRYPCLKLAMEAFEQGQAATTALNAANEITVAAFLAQQIRFTDIAGLNLAVLERMDLQEPASVEDVLQVDAIAREVARKQVIRLSR
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: RK36_GRATL
Sequence: MKVRASVKKICDKCRVIRRNRKIIIICNNAKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: BFR_STRCO
Sequence: MQGDPEVIEFLNEQLTAELTAINQYFLHAKLQDHKGWTKLAKYTRAESFDEMRHAEVLTDRILLLDGLPNYQRLFHVRVGQSVTEMFQADREVELEAIDRLRRGIEVMRAKHDITSANVFEAILADEEHHIDYLETQLDLIEKLGESLYLSTVIEQTQPDPSGPGSL
What is the function of this protein?
Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.
What are the official names of this protein?
Bacterioferritin, BFR.
What is the protein family that this protein belongs to?
Belongs to the bacterioferritin family.
Protein: IKKA_XENTR
Sequence: MEKPPVQHGAVCGPWDMKDRLGTGGFGNVCLYQNRETGELKAIKSCRLELSMKNKERWCQEIQIMKRLNHPNVVKACEVPPEMDFLVNDVPHLAMEYCAGGDLRKLLNKPENCCGLKESQVLNLMSDIGSGIQYLHEKRIIHRDLKPENIVLQECNGKTVHKIIDLGYAKDLDQGSLCTSFVGTLQYLAPELFENKPYSVTVDYWSFGTMVFECIAGFRPFLHNMQPFTWHEKIKKKDHKHIYAYEEMSGEIRFSSYLPQPNNLCSIIVDKIETWLQLLLNWDPIQRGGGMDCGRPQCFVLMDQILNLKIVHILNMTSAKIHSFHLQPEESLHTLQSRIETETGISTCNQELLLEMGVSLDPRKPASQCVIDGVKGWDSYMVYLFDKSKTVYEGPFQSRSLSECLNYIVQDSKVQLPIPQLRKVWAEAVHYVSGLKEDYSRLFQGQRAAMLSLLRFNTNLTKMKNTMVSASQQLGAKLQFFKRSIEIDLERYSDQMAYGISSEKMLRAWKEMEDKAVCFGKAGKIHFLDETIMGLHTEIVELQKSPCARRQGDVMEHLEQRAMELYKQLKPRSPDKAYSDSTEMVKILVQTVQGQDRVLKELFGHLSKLLGCKQKIIDLLPQIEMTVNNIKEADSSLMQMQAKRQREIWHLLKIACTQSSARSLGPASVETPITPRTSAWPDQSSSQALFSMLTTKDKSREILRHTIDKNSDYQKLLSSLILQTQTTMEQNSLMSLDFSWLNK
What is the function of this protein?
Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor.  Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines.
What are the official names of this protein?
Inhibitor of nuclear factor kappa-B kinase subunit alpha, I kappa-B kinase alpha, IKK-A, IKK-alpha, IkBKA, IkappaB kinase, Conserved helix-loop-helix ubiquitous kinase, Nuclear factor NF-kappa-B inhibitor kinase alpha, NFKBIKA.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and the nucleus.
Protein: PSB28_GLOC7
Sequence: MAQIQFARGLVEDAIPTIRLTRSRTGDSGTATFYFESPNIFADEQTQEVTGMYLIDSEGEIVSREVKGKFINGKPHAIEAILIMNSPDEWERFMRFMERYAQEHGLEFTKA
What are the official names of this protein?
Photosystem II reaction center Psb28 protein, Photosystem II 13 kDa protein, Photosystem II reaction center W protein.
What is the protein family that this protein belongs to?
Belongs to the Psb28 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: C15C1_BOMMO
Sequence: MLALIVLCFILFFYIISRRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIREVSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGDECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKELCSLVMRLFKLVDMSGGFLNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQENLQLGAPKDVIDAFLIDMLESQDDKPTLDDLQVVCLDLLEAGMETVTNTAVFMLLHVVRNEDVQRKLHQEIDDIIGRDRNPLLDDRIRMVYTEAVILETLRISTVASMGIPHMALNDAKLGNYIIPKGTFILLSLYELHHGPHWKDPETFRPERFLTKEGNILQDEWLIPFGIGKRRCIGEGLARSELFMFLTHILQKFHLRIPKNEPLPSTEPIDGLSLSAKQFRIIFEPRKTFKSI
What is the function of this protein?
Catalyzes the conversion of farnesoate to juvenile hormone III acid in juvenile hormone biosynthesis.
What are the official names of this protein?
Farnesoate epoxidase, Cytochrome P450 15C1, Protein dimolting, mod.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: RANB3_MOUSE
Sequence: MADLANEEKPAVAPSVFVFQKDKGQKRSAGSSSPEAGEDSDHEDGNYCPPVKRERTSSLTHSEEKSSGFRLKPPTLIHGQAPSAGLPSQKPREQQRGVLRPAVLQAPQPKVLSQTVPSSGTNGVSMPADCTGPATSVSPENLTQRSPSESAEETHTLEEKVPQKTPHGTSEEGHCEEEQAAPQAFVFGQNLRDRVKLMNENASVADVDSAAHPSSETPSATNYFLQYISSSADNATHSADNSTKFVFGQNMSERVLSPPKLNEANSDTSRETTHAQSGSESSSQEAAPKKESLAESAAAYTKATAWTCLLEKVEVITGEEAESNVLQIQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQMDKASEKSIRITATDAEDQGVKVFLISASSKDTGQLYAALHHRILALRSRAEQEQEAKAPPPEPGATRATEEEDSDEDAVLAPSGVTGAGTGDEGDGQAPGST
What is the function of this protein?
Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein.  Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction.  In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex.  Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1.  Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner.  Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export (By similarity).
What are the official names of this protein?
Ran-binding protein 3, RanBP3.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PYRB_COXBR
Sequence: MNELPLHLLNMRSLTRDHIEKLIQRANYFLTQGMEKNSVFETLKGHVVANLFFEPSTRTRNSFEIAAKRLGAMVLNPNLKISAISKGETLFDTIKTLEAMGVYFFIVRHSENETPEQIAKQLSSGVVINAGDGNHQHPSQALIDLMTIKQHKPHWNKLCVTIIGDIRHSRVANSLMDGLVTMGVPEIRLVGPSSLLPDKVGNDSIKKFTELKPSLLNSDVIVTLRLQKERHDNSVDIDAFRGSFRLTPEKLYSAKPDAIVMHPGPVNREVEINSDVADNQQSVILQQVRNGVAMRMAVLELFLLRDFRFF
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.