PharMolix/UniProtQA huggingface dataset:
Protein: PURA_HYPNA
Sequence: MAGVVVVGAQWGDEGKGKIVDWLSSRADVVVRFQGGHNAGHTLVIDGKVFKLALLPSGLVRGGKLSVIGNGVVVDPWHMLTEIEGIQAQGIEVSPESLVLADNASLILPWHKDIDAAREGALGAAQIGTTKRGIGPAYEDRVGRRAIRVADLADPAALDLKIERLLAHHRPLRAGLDLPEPDGAALKAALLEIAPQVLAYAQPVWKLLDEKVRRGSRILFEGAQGVMLDVDHGTYPFVTSSSVVAGNASAGSGVGPGAISYVLGLAKAYTTRVGAGPFPTEQDNDIGKRLGTVGHEFGTNTGRARRCGWFDSVMVRQACATSGVTGLALTKLDVLDGFEEIKICTAYKLNGKTIDYFPAGLTDQAAVEPVYETLKGWSGSTRGARSWTDLPPEAVVYVRRLEELVGKPCALVSTSPEREDVILMRDPFEG
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_CERS5
Sequence: MEGDIAEMGKFIGAGLATIGLGGAGIGVGHVAGNFLAGALRNPSAAPGQMANLFVGIAFAEALGIFSFLIALLLMFAV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYGB_LACGA
Sequence: MTKDYLFEIGTEEMPAHVVSRSVKQLADRTKKYLKENGLSFKDIKTYSTPRRLTILVEDLAEKQDDIDEVKKGPAKKIAQDKDGNWTKAAQGFARGQGMTTDDIYFEELKGTEYAYVHVQKEGKKASDILMGMSDIIKAMTFPTKMRWDSNDFEFVRPIHWMVSLLGSEVVPVKLLDVVAGRKTQGHRFLGDSVVLANADDYEEALKSQYVIADADERKGMILNQIQELVAQHNWKVNIDKGLLEEVTNLVEYPTVFAGSFDEKYLNIPDEVLITSMKDNQRYFEVYDENGKLINHFIAVRNGNSEYLDNVIAGNEKVLVARLDDAQFFYDEDKKYPLAHFVDKLKNVSFHDKIGSVAEHMARVHIIGDYLGKKFNISETEMKDFDRVSDIYKFDLVTSMVGEFAELQGVMGMHYARLTGEDENVSVAIKESYMPTSAEGDLPSTTVGSLLSIADKLDTIISFFGAGMIPSSSNDPYALRRNAYGIVRILLNEGWSLPVKDVLPELIQLLSGKTAAKLPKDAEAENEIADFIRDRVKQQLQVEKYDYDVIDAVLASSQQDPIQILAAAKTLQMHHDDADFKPVVESLTRITNILKKAKYRNAAKVDESLFQDVSEEELNAGVNALEENTDLSIADLYKGFVELQPVINNYFESNMILDKDEKVKNNRLAQLLKVNNLADRMGDLSKLVIK
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZBT17_MOUSE
Sequence: MDFPQHSQRVLEQLNQQRQLGLLCDCTFVVDGVDFKAHKAVLAACSEYFKMLFVDQKDVVHLDISNAAGLGQVLEFMYTAKLSLSPENVDDVLAVASFLQMQDIVTACHTLKSLAEPSSTTGESADASAVEGGDKRAKDEKAAATMLSRLDQARGSSSTGPGRELKEERGGQAESASSGAEQTEKADAPREPPPVELKPDPTSSMAAAEAEALSESSEQEMEVEPASKGEDGQEEEGAGPATVKEEGMHLDNGEPPEENEESAGTDSGQELGMEGQNLRSGTYGDRTESKAYGSIIHKCEDCGKEFTHTGNFKRHIRIHTGEKPFSCRECSKAFSDPAACKAHEKTHSPLKPYGCEECGKSYRLISLLNLHKKRHSGEARYRCGDCGKLFTTSGNLKRHQLVHSGQKPYQCDYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKRHLRIHSGEKPYVCTHCQRQFADPGALQRHVRIHTGEKPCQCVICGKAFTQASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANHIRHHDNIRPHKCSVCSKAFVNVGDLSKHIIIHTGEKPYLCDKCGRGFNRVDNLRSHVKTVHQGKAGIKILEPEEGGEVSVVTVDDMVTLATEALAATAVTQLTVVPVGAAVTADETEVLKAEISKAVKQVQEEDPNTHILYACDSCGDKFLDANSLAQHVRIHTAQALVMFQTDADFYQQYGPGSTWPAGQMLQAGELVFRPRDGTEGQPTLAESPPTAPDCLPPAE
What is the function of this protein?
Transcription factor that can function as an activator or repressor depending on its binding partners, and by targeting negative regulators of cell cycle progression.  Has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription.  Required for early embryonic development during gastrulation.  Plays a critical role in early lymphocyte development, where it is essential to prevent apoptosis in lymphoid precursors, allowing them to survive in response to IL7 and undergo proper lineage commitment.  Represses RB1 transcription; this repression can be blocked by interaction with ZBTB49 (By similarity).
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 17, LP-1, Polyomavirus late initiator promoter-binding protein, Zinc finger protein 100, Zfp-100, Zinc finger protein 151, Zinc finger protein Z13.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSMD8_MOUSE
Sequence: MFIKGRAAKTPRGEPRRSSRGGRKLAVVAPPPVLGSTSRPHFRRESIARRRCRKSGRRLAASRKMAATAATVNGSTTVSSSGPAATSVGILQAAAGMYEQLKDEWNRKNPNLSKCGEELGRLKLVLLELNFLPTTGTKLTKQQLILARDILEIGAQWSILCKDIPSFERYMAQLKCYYFDYKEQLPESAYMHQLLGLNLLFLLSQNRVAEFHTELERLPAKDIQTNVYIKHPVSLEQYLMEGSYNKVFLAKGNIPAESYTFFIDILLDTIRDEIAGCIEKAYEKILFAEATRILFFSTPKKMTDYAKKRGWVLGPNNYYSFASQQQKPEDSTIPSTELAKQVIEYARQLEMIV
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 8, 26S proteasome regulatory subunit RPN12, 26S proteasome regulatory subunit S14.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S14 family.
Protein: NUDC_VIBVU
Sequence: MLSNSDSKHGQKAYWCVVSGSDLWLVDGQLPLATSNELNLVAEKAQKIGSYNNHPVMWLNEADVEQSLEMHSLRECLHFPEPLFLLMSKAIQYGHMTQTMRFCPQCGGRNHLNHNQLAMQCGECRTLHYPRIFPCIIVAVRKQQHILLAQHPRHRSGMYTVIAGFVEVGETLEQCVAREVKEETGIEVTNIRYFGSQPWAFPSSMMMAFLADYHAGELKPDYSELADAKWFTSDNLPPVAPTGTIARALIEQTLLNMRSDS
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: ARH40_HUMAN
Sequence: MEPEPVEDCVQSTLAALYPPFEATAPTLLGQVFQVVERTYREDALRYTLDFLVPAKHLLAKVQQEACAQYSGFLFFHEGWPLCLHEQVVVQLAALPWQLLRPGDFYLQVVPSAAQAPRLALKCLAPGGGRVQEVPVPNEACAYLFTPEWLQGINKDRPTGRLSTCLLSAPSGIQRLPWAELICPRFVHKEGLMVGHQPSTLPPELPSGPPGLPSPPLPEEALGTRSPGDGHNAPVEGPEGEYVELLEVTLPVRGSPTDAEGSPGLSRVRTVPTRKGAGGKGRHRRHRAWMHQKGLGPRGQDGARPPGEGSSTGASPESPPGAEAVPEAAVLEVSEPPAEAVGEASGSCPLRPGELRGGGGGGQGAEGPPGTPRRTGKGNRRKKRAAGRGALSRGGDSAPLSPGDKEDASHQEALGNLPSPSEHKLPECHLVKEEYEGSGKPESEPKELKTAGEKEPQLSEACGPTEEGAGERELEGPGLLCMAGHTGPEGPLSDTPTPPLETVQEGKGDNIPEEALAVSVSDHPDVAWDLMASGFLILTGGVDQSGRALLTITPPCPPEEPPPSRDTLNTTLHYLHSLLRPDLQTLGLSVLLDLRQAPPLPPALIPALSQLQDSGDPPLVQRLLILIHDDLPTELCGFQGAEVLSENDLKRVAKPEELQWELGGHRDPSPSHWVEIHQEVVRLCRLCQGVLGSVRQAIEELEGAAEPEEEEAVGMPKPLQKVLADPRLTALQRDGGAILMRLRSTPSSKLEGQGPATLYQEVDEAIHQLVRLSNLHVQQQEQRQCLRRLQQVLQWLSGPGEEQLASFAMPGDTLSALQETELRFRAFSAEVQERLAQAREALALEENATSQKVLDIFEQRLEQVESGLHRALRLQRFFQQAHEWVDEGFARLAGAGPGREAVLAALALRRAPEPSAGTFQEMRALALDLGSPAALREWGRCQARCQELERRIQQHVGEEASPRGYRRRRADGASSGGAQWGPRSPSPSLSSLLLPSSPGPRPAPSHCSLAPCGEDYEEEGPELAPEAEGRPPRAVLIRGLEVTSTEVVDRTCSPREHVLLGRARGPDGPWGVGTPRMERKRSISAQQRLVSELIACEQDYVATLSEPVPPPGPELTPELRGTWAAALSARERLRSFHRTHFLRELQGCATHPLRIGACFLRHGDQFSLYAQYVKHRHKLENGLAALSPLSKGSMEAGPYLPRALQQPLEQLTRYGRLLEELLREAGPELSSECRALGAAVQLLREQEARGRDLLAVEAVRGCEIDLKEQGQLLHRDPFTVICGRKKCLRHVFLFEHLLLFSKLKGPEGGSEMFVYKQAFKTADMGLTENIGDSGLCFELWFRRRRAREAYTLQATSPEIKLKWTSSIAQLLWRQAAHNKELRVQQMVSMGIGNKPFLDIKALGERTLSALLTGRAARTRASVAVSSFEHAGPSLPGLSPGACSLPARVEEEAWDLDVKQISLAPETLDSSGDVSPGPRNSPSLQPPHPGSSTPTLASRGILGLSRQSHARALSDPTTPL
What is the function of this protein?
May act as a guanine nucleotide exchange factor (GEF).
What are the official names of this protein?
Rho guanine nucleotide exchange factor 40, Protein SOLO.
What are the subcellular locations of this protein?
Cytoplasm. Note=Concentrated in the perinuclear region.
Protein: RSMH_ENTFA
Sequence: MTEEFRHYTVLLKETVDGLQVKPDGVYVDCTLGGAGHSEYLLTQLNEHGHLYAFDQDQKALAHAKTRLQKYVDKGQVTFIKSNFRNIKEELAEHGVFHVDGILYDLGVSSPQLDEAERGFSYHQDAPLDMRMDQDAPLTAREVVNTYSYSELVKIFFRYGEEKFSKQIAREIERVREKQPIETTGELVEIIKTAIPAPARRKGGHPAKRIFQAIRIAVNDELGAVEESLEQAIDLLAKNGRISVITFHSLEDRIVKTMFKEYSTVQDLPPGIPVVPEEFQPELKVITRKPILPSDSELSENNRSRSAKLRIAEKIKSR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUXS_NEIM0
Sequence: MPLLDSFKVDHTRMYAPAVRVAKTMTTPKGDTITVFDLRFCVPNKEILPEKGIHTLEHLFAGFMRDHLNGNGVEIIDISPMGCRTGFYMSLIGTPSEQQVADTWLASMQDVLTVQDQSKIPELNEYQCGTYLMHSLAEAQQIAQNVLARKVAVNKNEELTLDEGLLNA
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: Y2421_SHEB2
Sequence: MAFWQSKTLAQMSATEWESLCDGCGKCCLNKLIDDETEDLYYTNAACLLLDHQTAGCQHYSDRFTHVPQCTVITIDNIHELTWLPDSCAYRRLAAGRELPSWHPLLTGSKEAMHLAGMSIQGKVVDERRVKDIEDHIVLWPLKDVD
What are the official names of this protein?
UPF0260 protein Sbal223_2421.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: MNME_STRPC
Sequence: MSITKEFDTITAISTPLGEGAIGIVRLSGTDALAIAQSVFKGKNLEQVASHTINYGHIIDPKTGTIIDEVMVSVMLAPKTFTRENVVEINTHGGIAVTNEILQLLIRQGARMAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMTIAVKQLDGSLSQLINDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLREKTQEFQSLLENLLRTAKRGKILREGLSTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNIKGVPLKLVDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTDQDRALLNLSQDSNRIILLNKTDLEQKIELEQLPADLIPISVLTNQNINLIEDRINQLFFDNAGLVEQDATYLSNARHISLIEKAVQSLEAVNDGLALGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3509_METJA
Sequence: MNYMKFMWNSEDGFIVEEQHKEEIPFEDWIVNTVEQLKNLQYTRYTFEELTPKTKNLEAYNKLLEILKKHTNMDIENNVKRIYHCIAENNNYKYEIAFYIVISKNWNE
What are the official names of this protein?
Uncharacterized protein MJECL09.
Protein: AFAM_BOVIN
Sequence: MKQLKLTGFVIFFFFLTESLTLPTQPQDVDDVRITQKFIDDNIGYITIIAFAQYIQEASFEEVEMLVKAMTEYRDKCLADRTLPECSKLANEVLLENICAMEGLPQKYNFSHCCHKVDFERRLCFFHNKKADIGLLPPLPTLDPEEKCQTYKNNRESFLNNYVYEVSRRNPFVFAPTLLTVAARFEEMTKTCCEEQEKANCFQTKAEPFIYYLKALSSYQKNACRALMKFGRQILQSINIAILSQKFPKIGFKQLTSLLEDVSSKYDGCCEGDVVQCIRGRSKVMSHICSKQDSISSKIKDCCEKKIPERGECIIYSNKDDRPNDLSLREAKFIESDNVCEKRDADQANFMAEFLYEYSRRHPELSTPELLRIAKVYKDLLKECCNMENPPECYRHAENRFNETTEKSLKIVQRECEHFQNLGKDDLKYHYLINLTKLAPQLSTEELTFLGKEMVMALTTCCTLSEEFACVDNLVDLVLGELCGINENRNINPAVDHCCKTNFAFRRSCFESLEADKTYVPPSTSQGLFTFHADLCQAHNEELQRKKDRFLVNLVKLKPELAGEELWSLLADFTNVVEKCCKAQEPEACFKEESPKLAAKSQAA
What is the function of this protein?
Functions as carrier for hydrophobic molecules in body fluids.  Essential for the solubility and activity of lipidated Wnt family members, including WNT1, WNT2B, WNT3, WNT3A, WNT5A, WNT7A, WNT7B, WNT8, WNT9A, WNT9B, WNT10A and WNT10B (PubMed:26902720).  Binds vitamin E.  May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient.  May be involved in the transport of vitamin E across the blood-brain barrier (By similarity).
What are the official names of this protein?
Afamin, Alpha-albumin.
What is the protein family that this protein belongs to?
Belongs to the ALB/AFP/VDB family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEMA_INBGL
Sequence: IVLLMVVTSNADRICTGITSSNSPHVVKTATQGEVNVTGVIPLTTTPTKSHFANLKGTQTRGKLCPNCLNCTDLDVALGRPKCMGTIPSAKVSILHEAKPVTSGCFPIMHDRTKIRQLPNLLRGYENIRLSTSDVINAETAPGGPYTVGTSGSCPNITNGEGFFETMAWAIPKNKTAMNPLTVEVPYICTKGEDQITVWGFHSDNETQMVILYGDSKPQKFTSSANGVTTHYVSQIGGFPNQTEDEGLKQSGRIVVDYIVQKPGKTGTIVYQRGVLLPQKVWCASGRSKVIKGSLPLIGEADCLHEKYGGLNKSKPYYTGEHAKAIGNCPIWVKTPLKLANGTKYRPPAKLLKERGFFGAIAG
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induce an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: RUTE_ECO57
Sequence: MNEAVSPGALSTLFTDARTHNGWRETPVSDETLRELYALMKWGPTSANCSPARIVFIRTAEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPQLFPHGDARSWFTSSPQLAEETAFRNSSMQAAYLIIACRALGLDTGPMSGFDRQHVDDAFFAGSTLKSNLLINIGYGDSSKLFARLPRLSFEEACGLL
What is the function of this protein?
May reduce toxic product malonic semialdehyde to 3-hydroxypropionic acid, which is excreted.
What are the official names of this protein?
Probable malonic semialdehyde reductase RutE.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family. HadB/RutE subfamily.
Protein: MT2_TRIRP
Sequence: MSCCGGNCGCGSACKCGNGCGGCKMNADLSYTESTTTETIVMGVGSAKAQFEGAEMGAESGGCKCGANCTCDPCTCK
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein-like protein 2, Metallothionein-like protein A, MT-A.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 15 family.
Protein: HEM1_MYCTA
Sequence: MSVLLFGVSHRSAPVVVLEQLSIDESDQVKIIDRVLASPLVTEAMVLSTCNRVEVYAVVDAFHGGLSVIGQVLAEHSGMSMGELTKYAYVRYSEAAVEHLFAVASGLDSAVIGEQQVLGQVRRAYAVAESNRTVGRVLHELAQRALSVGKRVHSETAIDAAGASVVSVALGMAERKLGSLAGTTAVVIGAGAMGALSAVHLTRAGVGHIQVLNRSLSRAQRLARRIRESGVPAEALALDRLANVLADADVVVSCTGAVRPVVSLADVHHALAAARRDEATRPLVICDLGMPRDVDPAVARLPCVWVVDVDSVQHEPSAHAAAADVEAARHIVAAEVASYLVGQRMAEVTPTVTALRQRAAEVVEAELLRLDNRLPGLQSVQREEVARTVRRVVDKLLHAPTVRIKQLASAPGGDSYAEALRELFELDQTAVDAVATAGELPVVPSGFDAESRRGGGDMQSSPKRSPSN
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: GATB_ARCFU
Sequence: MDDVVIGLEVHVQLNRLRTKLFCSCPLNYHQSPPNTHVCPVCLGMPGAMPVINKEAVKAAVKVAMALNAEIQPFTVFDRKNYFYPDLPKGFQISQYDRPLALGGYVTIELDGQEKRIQLKRVHMEEDPGKLSYKGSITTAKYSLIDYNRSGAPLLEIVTEPVMNSPKEARLFLNKLRMILEYLEVFDGDLEGAMRVDANISIRGSGRVEIKNISSFKGVEKALSYEIMRQKNLLQRGRSVVRETRHFDEARNITVSLRSKEEEQDYRYFPEPDLVPVLTEEIVREVEGTLPEMPEEKRERLKRQYGIGDNFAKVLILDVKMADYFEEVAKLVDPKLAASWIVDVLRGELNYRDWSFAKCWEVFKPEEFAKLLKYFEEDRITEKGVVEVIRTKLDEGGEIDAIIQKKGLFAIPKEEIIKFCKEAIEENPKAVEDYLSGKRQALNFLVGQVMKKTRGRADPADTAKLIEEMLS
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: Y3836_FRAAA
Sequence: MTFRAASDQIEVPAGVGLTAVGMAWVRARESARRDRLFDDPYAEAFVEAAGGPAAAGPAGAFARFIDVVDSHGVQRTRFFDDYLTRAADAGQRQFVLLAAGLDTRAHRLSWPAGTRLFEVDLPEMLTFKQAVLDTRHATARAERITVPADLAGDWSSALTRAGLRPRERTTWLVEGLLPYLDAEAAAHLLTTVGELSVPGSLLGFEYQADTWLLDELRATPELAEFATLLKGGLGESPLDWLPRHGWQVLQARLRSELAAEAGRPAPGPLADGFLVATRR
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase FRAAL3836.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: HSLV_AQUAE
Sequence: MEVKATTILAVRRDGKTAVGGDGQVTLGSSVIKHTARKIRKLYKGQVIVGFAGSAADGLALMERLEAKLEEYRGNLLKASVQLAKDWRMDKYLRRLEALLLAVDREHMLLISGNGDIIEPDEPVLAIGSGGDYARAAALALYRNTDLSAREIVEKSLKIASEICIYTNDKFVIEEI
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLYL_DICD3
Sequence: MKYLNCFISTGLAAFFLVNSTSVLAADCSSDLTSGISTKRIYYVAPNGNSSNNGSSFNAPMSFSAAMAAVNPGELILLKPGTYTIPYTQGKGNTITFNKSGKDGAPIYVAAANCGRAVFDFSFPDSQWVQASYGFYVTGDYWYFKGVEVTRAGYQGAYVIGSHNTFENTAFHHNRNTGLEINNGGSYNTVINSDAYRNYDPKKNGSMADGFGPKQKQGPGNRFVGCRAWENSDDGFDLFDSPQKVVIENSWAFRNGINYWNDSAFAGNGNGFKLGGNQAVGNHRITRSVAFGNVSKGFDQNNNAGGVTVINNTSYKNGINYGFGSNVQSGQKHYFRNNVSLSASVTVSNADAKSNSWDTGPAASASDFVSLDTSLATVSRDNDGTLPETSLFRLSANSKLINAGTKESNISYSGSAPDLGAFERN
What is the function of this protein?
Presents an endo-cleaving activity on polygalacturonate or partially methylated pectin.  Is effective in the maceration of plant tissue, and has an important role in soft-rot disease.  Is 280-fold less active against polygalacturonate than the major pectate lyase PelB.  When assayed on polygalacturonate, PelL releases oligogalacturonates of different sizes; upon prolonged incubation, PelL degrades the primary products to unsaturated tetramer and pentamer in addition to unsaturated dimer and trimer.  When assayed on oligogalacturonates (degrees of polymerization of 2 to 8), it preferentially forms unsaturated tetramer, and displays the highest activity on the octamer.
What are the official names of this protein?
Pectate lyase L, Pectate transeliminase, Pel9A.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 9 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DDL_SHEWM
Sequence: MSQINLLLLCGGGGDEHAISLMSADFLETSLAKEPEINLLRVELDGQGHYRTQDGRSCELTNRKEIRFAAEEQAPWPVDYVIPCIHGFPGETGDIQSYFDLIKLPFFGCDSESSSNCFNKVTAKMWFSALGVPNTPYIFLNELNQESIAQTKQALENWGSIFIKAASQGSSVGCYRVDSQDELVSSLEQAFSFSPYVIVEKTINARELEVAAYELNGEIVATKPGEIICASNTFYSFDEKYAANSKAETKVEADVSEEVAQQIQAYAIKVFKGMKLSHLSRIDFFLTEDNEILLNEINTFPGLTPISMFPKMLQNHGDDFTHYLYSNIKSQLVSA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRYAA_MANJA
Sequence: MDIAIQHPWFKRALGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSGISEVRSDRDKFVIYLDVKHFSPEDLTVKVLEDSVEIHGKHSERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPKVPSGVDTSHSERAIPVSREEKPSSAPSS
What is the function of this protein?
Contributes to the transparency and refractive index of the lens.  Acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions.  Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
What are the official names of this protein?
Alpha-crystallin A chain.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Protein: TAAR9_HUMAN
Sequence: MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQSSSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVETD
What is the function of this protein?
Orphan receptor.  Could be a receptor for trace amines.  Trace amines are biogenic amines present in very low levels in mammalian tissues.  Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative.  Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood.
What are the official names of this protein?
Trace amine-associated receptor 9, TaR-9, Trace amine receptor 9, Trace amine receptor 3, TaR-3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS14_SYNP6
Sequence: MAKKAMVERDRKRKKLVEKYAAKREALKEQFAAATSQSERLELHRKLQQLPRNSAPNRVRNRCWVTGRPRGYYRDFGLCRNVLREMAHQGLLPGVVKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: LYRM2_XENLA
Sequence: MGSRLPPAALTLKQFLVRQQVLGLYRRIVRAVRQIPGAADRQYLQDWARDEFRRNKGASEEIAIRMMISHGQRQLQELERALQLAKS
What is the function of this protein?
Involved in effecient integration of the N-module into mitochondrial respiratory chain complex I.
What are the official names of this protein?
LYR motif-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family.