PharMolix/UniProtQA huggingface dataset:
Protein: SYH_CLOB1
Sequence: MSLQAPKGTKDLLPTESYKWQYLENKFRNIAADFGCREIRTPVFEYTELFQRGVGETTDVVQKEMYTFEDKAGRSITLKPEGTSPAVRAFVEGRLFNETQPTKMYYFTPVMRYENVQKGRLRQHHQFGIEIFGAKDASVDAEVISIPVGIYKELGVEGVELNINSIGCPKCRKTYNEALKKYLSKNYDKLCSTCKTRFDKNPLRILDCKVDTCKEIVKDAPIILDYICDECKDHFEALKSYLDVLDIKYKVDPFIVRGLDYYSKTVFEFIIDDITICAGGRYDYLIEEIGGPSMPAVGFGMGIERLLLTLQEKAIEIPEEAYVDLYLGNMGDKAKLEVLKLAKELRDRHIKCEIDHMGKSVKAQMKYANRIGAKYSMVLGEEELNTGKVSLKRMEDGQQIEVDIKEIDTLIKVFK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_THIDA
Sequence: MADRDVQARAAALRREIERHNYAYYVLDAPTIPDAEYDRLYHELEALEAAHPELVAADSPTRRVGGQPLAGFKPVRHAVPMLSIRTETDTTAAGARAFDVRVRKELGLAPADPPVEYAAELKFDGLAINLRYEAGVLVAAATRGDGETGEDVTQNVRTVRTIPLRLHGDAPPAVLEVRGEVFMRRDDFERYNAQQRAAGKPTLVNPRNGAAGSIRQLDPAIAGQRPLSFYAYGLGEVVGWPDAPATHGATLDALQGLGVPVSAERCVCNGVDDLIAFHDDIAARRDQLPFDIDGVVYKVNAFALQRELGFLTREPRWAVAHKYPAQEQLTTVLGIGVHVGRTGALTPVARLAPVFVGGVTVTNATLHNQDEIDRKDTRVGDTVIVRRAGDVIPEIVATVLERRPQPEPPRFNILQSYPVCPECGSHVVRLEGEAVARCTGGLYCPAQRKQALLHFASRRAMDIDGVGEKLVDQLVSRELVRTPADLYRLPLETLAGLERMAEKSARNLIQAIETSKSTTLARFIYALGIRNVGETTARDLARHFGALDALLGANETALLGVRDVGPIVAQSIAQFFAEPHNLEVVGKLRALGVHWPETTGMQQSGGILSGKTLVLTGTLPALTRDQAKERIESAGGKVAGSVSKKTDYVVAGEEAGSKLAKARELGVTILDEEELLALLGSNKKNG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RLMN_BRUA4
Sequence: MSISFDLTIDDTRDQLARHARASLEAKPSLIGMSREEMAEALIKAGVPERQVKMRISQLWHWLYVRGVSDFADMRNISKDLRAMLAQHFTIARPEVVEEQISQDGTRKWLFRFPPRGAGRPVEIESVYIPEEGRGTLCVSSQVGCTLTCSFCHTGTQKLVRNLTSEEILAQLLTARDRLGDFPDKDTPDGAMVPAEGRKITNIVMMGMGEPLYNFEEVKKALLIASDGDGLSLSKRRITLSTSGVVPEIYRTGDEIGVMLAISLHAVRDELRDILVPINKKYPLEQLIKACREYPGLSNAKRITFEYVMLKDINDSLEDAKLLVKLLQGIPAKINLIPFNPWPGTNYQCSEWEQIEKFADYVNAAGYASPIRTPRGRDILAACGQLKSESERMRKSERLALEAMMIAGHGE
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_BACP2
Sequence: MAKKEEHVRKPDWLKIKLNTNENYTGLKKMMRENNLNTVCEEAKCPNIHECWAVRRTATFMILGSVCTRACRFCAVKTGLPTELDLQEPERVADSVALMNLKHAVITAVARDDQKDGGAGVFAETVRAIRRKSPFTTIEVLPSDMGGNYDNLKTLMDTRPDILNHNIETVRRLTPRVRARATYDRSLEFLRRAKEMQPDIPTKSSIMIGLGETKEEIIEVMDDLLANNVDIMAIGQYLQPSKKHLKVQKYYHPDEFAELKEIAMAKGFSHCEAGPLVRSSYHADEQVNEASKKRQAQA
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNF_ECO27
Sequence: MGLMWGLFSVIIASAAQLSLGFAASHLPPMTHLWDFIAALLAFGLDARILLLGLLGYLLSVFCWYKTLHKLALSKAYALLSMSYVLVWIASMVLPGWEGTFSLKALLGVACIMSGLMLIFLPTTKQRY
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF, L-Ara4N-phosphoundecaprenol flippase subunit ArnF, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnF.
What is the protein family that this protein belongs to?
Belongs to the ArnF family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL9_GRAFK
Sequence: MEVILKKDVDNLGFKDDLVAVKNGYGRNYLIPHGFAELATPSARKVLSETLKQRAYKEQKHIDEAKKQAEKLNNLEIKITAKAGAGDKLFGSITNGDLADALAKEGVEIEKKYISIAGGNIKRLGQYDATLRFHREVISNFSFDVVGDA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: RL14_SHIB3
Sequence: MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIKEAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLNNNSEQPIGTRIFGPVTRELRSEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: APT_ACHLI
Sequence: MDLKAHIAAVKDFPKEGILFRDITPLMLDGKAFKYASDQFTEFARSKKADLIVGPEARGFIFGCPVAVNLGVGFAPVRKPGKLPRASVTVSYDLEYGSNSLSLHEDAVKPGQRVVIIDDLLATGGTMQATVELVEKLGGIVVGLAFLIELDDLEGRKLLKNYDVKTLINY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR16_CYACA
Sequence: MIKIRLKRYGKKNRPTYRIVLIESQKPRDSKTIEELGHYDPLLKQANFKFDEIMKRVGQGARLTSRVRYILKQFS
What are the official names of this protein?
30S ribosomal protein S16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SCAR5_BOVIN
Sequence: MENKAMYLHATVSDRDSSSIFEEPFDGRSLSKLNLCEDGPCHKGRAGGCCTQLGSLSALKHAVLGLYLLVFLILVGIFILAVSRPRSSPDDLKALTRNVNRLNESFRDLQLRLLQAPLQGELSEQVWKAHDALQNQSDSLLALAGAVQRLEGALWGLQAQAAQSEQAVVLLRERAAQQSDAAQLELYQLQVDSNRSQLLLRRHAGLLDGLARRVGALSDELADVGGALRGLNLSLSYDVALQGTRLRDLRVLVSNASEDARRLRLAHRGLELQLKQELAVLNGVTEDLRLKDWEHSIALRNITLAKGPPGPKGDPGDAGKEGEPGIPGLPGLRGLPGERGTPGLPGPKGDEGKLGATGPMGMRGFKGDRGPKGEKGEKGDRTVDASGVEAVMVRLVNGSGLHQGRVEVYHERRWGTVCDDGWDKKDGDVVCRMLGFPGAEDVHRTAQFGQGTGRIWMDDVACKGTEESIFRCSFSKWGVTNCGHAEDAGVTCKRH
What is the function of this protein?
Ferritin receptor that mediates non-transferrin-dependent delivery of iron.  Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell.  Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways.  Ferritin mediates iron uptake in capsule cells of the developing kidney.  Preferentially binds ferritin light chain (FTL) compared to heavy chain (FTH1).
What are the official names of this protein?
Scavenger receptor class A member 5.
What is the protein family that this protein belongs to?
Belongs to the SCARA5 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: GCS21_FRACC
Sequence: MQIPFSSSSSTSLGIEWELQLVDQQSRELRGEASGILHELRAKVGECEAAKAKHELFESTIEVITGVCDSVEEATADLSGTVSLLRDLAERRGIGLMCSGTHPASDYMGQRITEDHRYFRLVSQMQWLARRLLIFGVHVHVGVRSADKAMPIVNALMAYVPHFLALSASSPYWLGGDTGLASSRSQVFASLPTAGLPYPLEDWPGFESFMETLIVSGTIETIREVWWDIRPHPNFGTVELRVCDGLPSLMEVGAVAALAQCLVDRMNTQIDRGYRLPTPQRWLVQENKWRAARYGLDAQIIVDGRGGIRPVRDDITDLVEDLLPVAHRLGCSSELSDTLTILRTGASYIRQRDAARRAGGDLTRVVDTLLEEMNTGRPVVDG
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2-1, Gamma-glutamylcysteine synthetase 2-1, GCS 2-1, Gamma-GCS 2-1.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: ACT_TRYCR
Sequence: MSDEEQSAIVCDNGSGMVKAGFSGDDALCHVFPSIVGRPKNEQAMMGSASKKLFVGDEAQAKRGVLSLKYPIEHGIVTNWDDMEKIWHHTFYNDVRVNPESHSVLLTEAPMNPKQNREKMTQIMFETFGVPAMYVGIQAVLSLYSSGRTTGIVLDAGDGVTHTVPIYEGYSLPHAIRRMDMAGRDLTEYLMKLLMESGMTFTTSAEKEIVRNVKEQLCYVALDFDEEVTNSAKTVNEEPFELPDGTIMQVGNQRFRCPEALFKPMLIGLDEAPGFHEMTFQSINKCDIDVRRDLYGNIVLSGGTTMFKNLPERLGKEISNLAPSSIKPKVVAPPERKYSVWIGGSILSSLTTFQTMWIKKSEYDEAGPSIVHNKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PRO1_DACGL
Sequence: NVQLDPFFQEQQQYYPQQQAFFLLQQQQN
What are the official names of this protein?
Prolamin alpha-1.
Protein: SOPE_SALTI
Sequence: MTKITLSPQNFRIQKQETTLLKEKSTEKNSLAKSILAVKNHFIELRSKLSERFISHKNTESSATHFHRGSASEGRAVLTNKVVKDFMLQTLNDIDIRGSASKDPAYASQTREAILSAVYSKNKDQCCNLLISKGINIAPFLQEIGEAAKNAGLPGTTKNDVFTPSGAGANPFITPLISSANSKYPRMFINQHQQASFKIYAEKIIMTEVAPLFNECAMPTPQQFQLILENIANKYIQYTP
What is the function of this protein?
Activator for both CDC42 and RAC1 by directly engaging these Rho GTPases and acting as potent guanine nucleotide exchange factor (GEF).  This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, promoting bacterial entry into non-phagocytic cells (By similarity).
What are the official names of this protein?
Guanine nucleotide exchange factor SopE, Effector protein SopE, Toxin SopE.
What is the protein family that this protein belongs to?
Belongs to the GEF (guanine exchange factor) SopE family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the type III secretion system 1 (SPI-1 TTSS).
Protein: HTPX_CELJU
Sequence: MLRIGLFLLTNLAVLVVAGVVLSLLGVGNYRTADGLDLTNLLIFCAVFGFVGSFISLFLSKWMAKKTMGVQLIEQPRNADEKWLVDTVVELSQKAGIKTPEIGVFAAQESNAFATGWNRNDALVAVSLGLLQRFERDEVKAVLAHEIGHVANGDMITLSLIQGVVNTFVMFFARIIGDLVDRVIFKNEEGRGIAFFITTIVAELVLGILASMIVAAFSRYREYRADAAGATLADRGAMIRALQRLQAEMSAGVESPLPSSMRAFGISGGVRNLFASHPPLEARIQALRDSAHG
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LSPA_SHELP
Sequence: MPSSWKESGLRWYWVVVLVFVADQLSKQWVLANFDLRESINLLPFFNFTYVRNYGAAFSFLNDAGGWQRWLFTLVAVGFSTLLTVWLRKQPKGLWRLNLAYTLVIGGALGNLIDRLQHGFVVDFLDFYWKTSHFPAFNIADSAICVGAGLIILDSFISERKPNGEDVAKG
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COX3_BOSMU
Sequence: MTHQTHAYHMVNPSPWPLTGALSALLMTSGLAMWFHFNSTALLMIGLTTNMLTMYQWWRDIIRESTFQGHHTPAVQKGLRYGMILFIISEVLFFTGFFWAFYHSSLAPTPELGGCWPPTGIHPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGDRNHMLQALFITITLGVYFTLLQASEYYEAPFTISDGVYGSTFFVATGFHGLHVIIGSTFLIVCFFRQLKFHFTSNHHFGFEAAAWYWHFVDVVWLFLYVSIYWWG
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NANK_YERPB
Sequence: MGKGLALDIGGTKIAAAVVTESGMLIGRQQIATPRGGAGQLAAALETLIAPYRHQVDFIAVASTGIISGGRLTALNPANLGGLADFPLYDCIRSISDLPCVLLNDGQAAAWAEYQALGDKNDNMMFVTVSTGVGGGIILNKKLLVGQRGLAGHIGHTLSDPHGVLCGCGRRGCVESVASGTAIGAETLGWKQPVSAATVFDMAQQGDAQAGKVINRSAAAIAQMLADMKMALDLEVVILGGSVGLAVGYLERVVAAQKTLPGIYRVPVQEAHHRQDSGLLGAALWARTSL
What is the function of this protein?
Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P.
What are the official names of this protein?
N-acetylmannosamine kinase, ManNAc kinase, N-acetyl-D-mannosamine kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NanK subfamily.
Protein: PROA_BRASO
Sequence: MTAPLKAIDGSADLPQLMNDLAKRARAAARVLALAPAEQKNRALEAMERRIRARADVIIAANAEDVAEAKAVGVTPSFVDRLTLTPARVAAMADGIAVVRGVADPVGVVTESWQRPNGMTIERVRVPLGVIGVIFESRPNVAADAGVLCLKSGNAVILRGGSDSFRSCRAIHECLVEGLREAGLPDTAITLVPTRDRAAVGLLLSGLNGGVDVIVPRGGKSLVARVEAEARVPVFAHLEGVNHVYVDGAADLDMAKSIVLNAKMRRTGVCGAAETLLIDRASQDKIKPLVDMLIGAGCEVRGDEAVRAADARVTPANNEDWDTEYLDAIIAAKVVDGVDGAIAHIHAHGSHHTDAIVTQDNKVADKFLNEVDSAIVLHNASTQFADGGEFGFGAEIGIATGKFHARGPVGVEQLTSFKYRIHGTGQTRP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDM8_XENTR
Sequence: MHRSVPEQVSAELPATLEQFQITLGADVEDRVEECVREAARCLYRGAIVQCGALGELLIDYSWEKLNARNWREVGREWRAVYSYGCLFRAVGLCSVTGSIEEALQVCDIGLLMGAEIMDNLLGRIISVLQRIAPSREETKLEAERGVREPGLESSKLHSPGEHSNKKSFASVTGRKRIREGPEADFDPKGCSISEKVPCLLVPVLDSETAIPKLHCPSLEHFRDHYLVPQKPVVLEGVIDHWPCLKKWSVEYIQRVAGCRTVPVELGSRYTDAEWSQRLMTVNEFITKYILDKQNGIGYLAQHQLFEQIPELKEDICIPDYCCLGEASEDEITINAWFGPAGTVSPLHQDPQQNFLAQIVGRKYIRVYSVAETEKLYPFDSSILHNTSQVDVESPDQNKFPRFSQASYQECILSPGQVLFIPVKWWHYIRALDLSFSVSFWWS
What is the function of this protein?
Histone demethylase required for G2/M phase cell cycle progression (By similarity).  Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator (By similarity).  May play a role in the regulation of the circadian clock (By similarity).
What are the official names of this protein?
Lysine-specific demethylase 8, JmjC domain-containing protein 5, Jumonji domain-containing protein 5.
What are the subcellular locations of this protein?
Nucleus.
Protein: HTPX_JANMA
Sequence: MKRIFLFIATNIAVIAVMSVVLSLLGVDRFISQAGLNLPMLLVFSLVVGFTGSIISLLISKPMAKWSTGARVIDAPSSSTELWLIDTVSKLAQRAGIKMPEVAVYDGEPNAFATGAFRDSALVAVSTGLLQSMTKDEVEAVLAHEVAHVANGDMVTMTLVQGVVNTFVVFLSRVVGYFVDRAISRDNNNSQGIGYTITVIVSQIVFGIAASVIVAWFSRHREFRADAGAAKLLGSPQPMMKALARLGGIEPTSLPEGLASLGINDKPGFAALFSSHPPIEDRIAALRSLQ
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TCP4_CHICK
Sequence: MPKSKELVSSSSSASDSDSEVDKKAKRKKQAAPEKPVKKQKTGESSKGAASSKQSSNRDENMFQIGKMRYVSVRDFKGKVLIDIREYWMDQEGEMKPGRKGISLNPEQWNQLKEQISDIDDAVRKL
What is the function of this protein?
General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery.  May be involved in stabilizing the multiprotein transcription complex.  Binds single-stranded DNA.  Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA) (By similarity).
What are the official names of this protein?
Activated RNA polymerase II transcriptional coactivator p15, SUB1 homolog.
What is the protein family that this protein belongs to?
Belongs to the transcriptional coactivator PC4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FADA_PSEE4
Sequence: MSLNPRDVVIVDFGRTPMGRSKGGMHRNTRAEDMSAHLISKLLERNDKIDPKEVEDVIWGCVNQTMEQGWNIARMASLMTPIPHTSAAQTVSRLCGSSMSALHTAAQAIMTGNGDVFVIGGVEHMGHVSMMHGVDPNPHLSLHAAKASGMMGLTAEMLGKMHGITREQQDLFGVRSHQLAHKATVEGKFKDEIIPMQGYDENGFLKVFDFDETIRPETTLEGLASLKPAFNPKGGTVTAGTSSQITDGASCMIVMSGQRAMDLGIQPLAVIRSMAVAGVDPAIMGYGPVPSTQKALKRAGLTMADIDFIELNEAFAAQALPVLKDLKVLDKMDEKVNLHGGAIALGHPFGCSGARISGTLLNVMKQNGGTLGVATMCVGLGQGITTVFERV
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_TRIEI
Sequence: MNFQSVIATLNQFWSDRGCLIAQSYDTEKGAGTMNPHTFLRAIGPEPWSVAYVEPCRRPTDGRYGENPNRFQHYYQYQVLMKPSPNNIQDLYLDSLRALGIRPEDHDIRFVEDNWESPTLGAWGVGWEVWLDGMEITQFTYFQQCGSIDCRPVSIEITYGLERLAMYLQEVDAITKIAWTDNITYGDVYLQGEIEQCSYNFEASSPDFLFNLFGLYEQEAKQLIKRELVLPSLDYVLKCSHSFNLLDARGVISVTERTRYIGRIRNLARQVGQLYLQQREKLNFPLLKETMEAA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_CAMC1
Sequence: MRIFDTSKREKVEFSPIKDGEVSIYLCGPTVYDDAHLGHAKSAVSFDLLRRVLKALGCKVKFARNYTDIDDKILNKMAQTGQSLEEITNKYIAHYESDMGALNVLDPDFKPKATQCLEAIISYIKVLMDRGVAYKTSDGIYFDTSKDSGYFSISGKDNNTDLIARVASFGEKRDEKDFVLWKFDEKWYESPFGKGRPGWHTECVAMIREFLSDKENDKFEIDIHAGGIDLLFPHHENEASQCRCAYHKNLSKYWMHNGFIKVNNEKMSKSLNNSFFVKDALKNVHGEVLRYYLLTSHYRAHFNYSDEDLVASKKRLDKIYRLKKRVDGVQAGMANESFKSELLEALSDDLNASKALASVDEFVKTANERLDNNPKDKAYKAEVVANLELIGEILGIAITNYVEYFQFGVSDEQKEHIQKLLDERAVAKKERNFARADEIRDELAKMNISIMDTPNGAVWERNNE
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_KLEP3
Sequence: MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTMNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCQVIPVLEVPPSAFTPPPKVDSAVVRLVPHRTMPYPVKEVRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTELGVDPAVRAENISVEQYCKMANWLSNNLPSKES
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPS1_SCHPO
Sequence: MLISTFVFLLYEVTALSTAIHVTKSYTHTRTGTSFFMYQKEAFYRGRSSTRQFNNTRSPSGRSASRSSNFSHRSSSRDSFSSNRSYSSSLSRSPEEPLRTILVENLTRNVTKEHIAEIFGIYGLIDHIFMPIYKKSELNKGYCYIEYVYHDQAANAVDKMNNAELDGEELFVSIKRFPFESLHKNHKHYENSYRPSRSQNNSHYNDKSFHRSRYSRARSRSPGSNISEYSDQSPPYHSYRHRP
What is the function of this protein?
Putative component of the spliceosome which enhances the formation of the ATP-dependent A complex of the spliceosome.  may participate in mRNA 3'-end cleavage.  Also mediates increase of mRNA abundance and translational efficiency (By similarity).
What are the official names of this protein?
RNA-binding protein with serine-rich domain 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: KUNIH_RHIMP
Sequence: MKCIILLAVLGTAFAQRNGFCRLPADEGICKALIPRFYFNTETGKCTMFSYGGCGGNENNFETIEECQKACGAPERVNDFESADFKTGCEPAADSGSCAGQLERWFYNVQSGECETFVYGGCGGNDNNYESEEECELVCKNM
What is the function of this protein?
Midgut thrombin inhibitor that plays a major role in keeping the midgut microenvironment at low hemostatic and inflammatory tonus (PubMed:18286181) (By similarity).  Also inhibits FXIa (F11), kallikrein (KLK1), neutrophil elastase (ELANE) and cathepsin G (CTSG), which play a role in the contact pathway of the coagulation cascade (PubMed:18286181) (By similarity).  Also abrogates platelet aggregation by cathepsin G and plasmin, and attenuates tissue factor (F3) pathway inhibitor cleavage by elastase (PubMed:18286181) (By similarity).  In vivo, inhibits thrombosis and promotes bleeding in mice (By similarity).
What are the official names of this protein?
Boophilin-H2.
What are the subcellular locations of this protein?
Secreted.