PharMolix/UniProtQA huggingface dataset:
Protein: IL18B_VACCW
Sequence: MRILFLIAFMYGCVHPYVNADEIKCPNLNIVTSSGEFRCTGCVKFMPNFSYMYWLAKDMRSDEDAKFIEHLGEGIKEDETVSTIDGRIVTLQKVLHVTDTNKFDNYRFTCVLTTIDGVSKKNIWLK
What is the function of this protein?
Soluble IL18-binding protein that may modulate the host antiviral response.
What are the official names of this protein?
Interleukin-18-binding protein, vIL-18BP.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG022 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ECD_MOUSE
Sequence: MEGSGKLAMVEDAVEYHLFLIPDKARGTEEHREILQKYIERIMTQFAPILVPYIWQNQPFNLKYKPAKGGVPAHMYGMTKFGDNIEDEWFIVYVIKQITKEFPELVARVEDNDGEFLLIEAADFLPKWLDPDNSANRVFFHHGELCIIPVPRKSERIPWLPMTPPTIQQALSIISAHPEAVLASESIQAAVDRRVSGYPERVEASLHRAHCFLPAGIVAVLKQQPRLLSAAVQAFYLRDPIDLRACRVFKTFLPETRIMASVTFTKCLYAQLVQQKFVPDRRSGYGLPPPSHPQYRAYELGMKLAHGFEILCSKCSPHFSDSRKSLVTASPLWASFLESLKRNDYFKGLMDGSAQYQERLEMAKNYFQLSIHRPESSLAMSPGEEILTVLQTQPFDVAELKTEEADLPPEDDDQWLDLSPDQLDQLLQDAAGRKESQPGPQKEELQNYDVAQVSDSMKAFISKVSSHKGAELPRDPSEAPITFDADSFLNYFDKILGAKPQESDSEDDPGEEDVEGVDSDDDVGFEAQESESLKGALGSLKSYMARMDQELAHTSMGRSFTTRERLNKDPPSHTANDNSDEEDSGAGDCAVEAVDVDLNLISNILESYSSQAGLAGPASNLLHSMGVRLPDNADHNPQVSQ
What is the function of this protein?
Regulator of p53/TP53 stability and function.  Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP.  May be involved transcriptional regulation.  In vitro has intrinsic transactivation activity enhanced by EP300.  May be a transcriptional activator required for the expression of glycolytic genes (By similarity).  Involved in regulation of cell cycle progression (PubMed:26711270).  Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins (PubMed:19640839).  The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex.  May play a role in regulation of pre-mRNA splicing (By similarity).
What are the official names of this protein?
Protein ecdysoneless homolog.
What is the protein family that this protein belongs to?
Belongs to the ECD family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYH_IDILO
Sequence: MNDLLPEQSPAWQQVEAVIRRVAASYGYSEIRMPVLESTQLFKRSIGEVTDIVEKEMYTFDDRNGESVTLRPEGTASCVRAGNQHGLLYNQIQRLWYMGPMFRYERPQKGRYRQFHQFGIETFGLESADADAEVILLSARLWREFGLADQVELQLNSLGSNEARANYRDALKAYLSDYESELDDDSKRRLESNPLRILDSKDEKTQKILEGAPSLSEYWDAESKEHFEQLTARLEAAGISYTLNERLVRGLDYYNRTVFEWVTTALGAQGTVCAGGRYDGLVEQLGGKATPAVGFAMGMERLVLLLQEQGKLTPRRVVDAYLMPLGEEAELNAPRIAEQLRNELPELRLVSHCGGGSMKKQMKKADKSGAQVALIIGADEIAQQLVTVKPLRTAEEQQTLGWQALIEFLQPLTRG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PORED_DROME
Sequence: MAPPENGILEVLENLLDRYKINLLQMMFGTFIATIVFFGGLMTFVEKYLPNSIRQSFRYGKHSFKGETDPLVAWLEVPKSWFKHFYTFALFWSWLAFYVLVSTVREQKEAPEYVLQFLDIMGGGRSHRKVEIDSTTACVGAFMLTLQCTRRFYETNFVQIFSKKSKINLSHYAVGYVHYFGAVIALLSNTSGFVRGSKPMEFSLDKLTSQQILYLGVFFLAWQQQYASNMILVNLRKDPRTGSVKTEKHLLPKGGLFNLLSSPHMFLEVVMYFCIADLYMPVRIWRLIFLWVASNQTINALLTHKWYQETFREYPKNRRAIIPFLL
What is the function of this protein?
Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol.  Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation.  Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism (By similarity).
What are the official names of this protein?
Polyprenol reductase.
What is the protein family that this protein belongs to?
Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y175_HELPS
Sequence: MDFSQLGGLLDGMKKEFSQLEEKNKDTIHTSKSGGGMVSVSFNGVGELVDLQIDDSLLEDKEAMQIYLMSALNDGYKAVEENRKNLAFNMLGNLGNFAKL
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein HPSH_00175.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: TRUA_ALCBS
Sequence: MTRIALGIEYDGTDFRGWQMQQSGVRTVQECLEAALSKVANHSVTVVCAGRTDAGVHGTGQVVHFDSDAPREMKSWIMGGNTNLPRDVTIRWAVPVSDDFHARFSAVSRRYRYVIYNHARPPALYRSQVTWNHRPLDVAAMREAASYLVGHHDFTAYRSVHCQAKSPLKTLHSLELYEQGKVLVLEAHANAFLMHMVRNIAGVLMKVGAGKKPPVWAKDVLECRDRRLGAATAPPFGLYLVEIEYPELFALPDEPLGPLWLPDRLEA
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: MU160_SCHPO
Sequence: MEKMESTEEWEALLSSSSNGDELTMKLIRNGLAKGFKSQKAAGDAGLYSRFLPYHFTESVSNDSFSSLPWQIFANSVAGNSPLQNEAWAFLMDNEDFFLPVPMNPAQCTALEIALWSLIRVDDQRLFELCHSKSGIRLLSIIFDFDSHPDWLREDVMFNIAERILKSNFPNVLVNVASKIGPKSIYFLIDCMSHKIKLKETATGFYVILDVLSCVGRQFASVLEECFTKEISSAGLDHINHFSEIVMLGVDLLYRDYVSYDTTISLKNDDSSSLGDMEFETSQPSSSISEIIHLLAVLDKRIPKKTLVEKTYASSMELQELYNAVVGVKRECVRFIAFICSKFSTAPDLVRHFNGVALIISQANYDDWNPYIREISVLCTRLLLQNNIENQKIIGGLTPITTTHSDALEEAGFTSYINDKGKVVLQPKTAKNSH
What are the official names of this protein?
Meiotically up-regulated gene 160 protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GUAA_SHESA
Sequence: MSDIHEHKILILDFGSQYTQLIARRIREIGVYCELWAWDVTEAQIREFAPNGIILAGGPESVTADNSPRAPEYVFNAGVPVLGICYGMQTMSEQLGGKVIQGVGEGEFGYAQIEMLAQSALFKDIEDAVSADGKSLLDVWMSHGDKVSAIPEGFVAVAKTDTCPFAAMSCEEKRFYGVQFHPEVTHTRQGMRMLSHFALDICGCAANWKPSSIIEDAIERLKKQVGDDEVILGLSGGVDSSVVAMLLHRAIGKKLTCVFVDNGLLRLNEAKQVMEMFGDHFGLNIVHVDAENRFLDALKGEADPEAKRKIIGRVFVEIFDEEAKKCVNAKWLAQGTIYPDVIESAGSATGKAHVIKSHHNVGGLPDDMELGLVEPLRELFKDEVRKIGLELGLPYNMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEIDGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: Y2133_ARCFU
Sequence: MLIALLLISYQLIKHGYRAADIKNLYTILEGEELRRQKDLSAKLRWGIVDEILWTIIVANGAILFTAHYVLIGLKILDLIAIFVVMLSGVMLYAPLAFLFLYPVVRAFEKNFPPSNPQFLLSHGLICTVSSLIVYEKLEQLWWDPLLVGFFWIAAGFVSFFTNRRFEVLVFLLLIAPLALLSVKCPGAILPILLAKSECSLRIQATFLVKLAVLIFASLAAVALVLQVFGYKSLRELSEKRKAAIKQGKYNPLRDPIIWIAWIMLTSLGLLIASFMERGEISPNML
What are the official names of this protein?
Uncharacterized protein AF_2133.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NEMF_HUMAN
Sequence: MKSRFSTIDLRAVLAELNASLLGMRVNNVYDVDNKTYLIRLQKPDFKATLLLESGIRIHTTEFEWPKNMMPSSFAMKCRKHLKSRRLVSAKQLGVDRIVDFQFGSDEAAYHLIIELYDRGNIVLTDYEYVILNILRFRTDEADDVKFAVRERYPLDHARAAEPLLTLERLTEIVASAPKGELLKRVLNPLLPYGPALIEHCLLENGFSGNVKVDEKLETKDIEKVLVSLQKAEDYMKTTSNFSGKGYIIQKREIKPSLEADKPVEDILTYEEFHPFLFSQHSQCPYIEFESFDKAVDEFYSKIEGQKIDLKALQQEKQALKKLDNVRKDHENRLEALQQAQEIDKLKGELIEMNLQIVDRAIQVVRSALANQIDWTEIGLIVKEAQAQGDPVASAIKELKLQTNHVTMLLRNPYLLSEEEDDDVDGDVNVEKNETEPPKGKKKKQKNKQLQKPQKNKPLLVDVDLSLSAYANAKKYYDHKRYAAKKTQKTVEAAEKAFKSAEKKTKQTLKEVQTVTSIQKARKVYWFEKFLWFISSENYLIIGGRDQQQNEIIVKRYLTPGDIYVHADLHGATSCVIKNPTGEPIPPRTLTEAGTMALCYSAAWDARVITSAWWVYHHQVSKTAPTGEYLTTGSFMIRGKKNFLPPSYLMMGFSFLFKVDESCVWRHQGERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLEVITHELQDFAVDDPHDDKEEQDLDQQGNEENLFDSLTGQPHPEDVLLFAIPICAPYTTMTNYKYKVKLTPGVQKKGKAAKTALNSFMHSKEATAREKDLFRSVKDTDLSRNIPGKVKVSAPNLLNVKRK
What is the function of this protein?
As part of the ribosome quality control complex (RQC), a ribosome-associated complex, mediates the extraction of incompletely synthesized nascent chains from stalled ribosomes as well as their ubiquitin-mediated proteasomal degradation.  Thereby, frees ribosomes from the stalled translation complex and prevents the accumulation of nascent polypeptide chains that are potentially toxic for the cell.  It is responsible both for selective recognition of stalled 60S subunits by recognizing an exposed, nascent chain-conjugated tRNA moiety and the recruitment of the E3 ubiquitin-protein ligase LTN1 to the ribosome quality control complex (PubMed:25578875).  May indirectly play a role in nuclear export (PubMed:16103875).
What are the official names of this protein?
Ribosome quality control complex subunit NEMF, Antigen NY-CO-1, Nuclear export mediator factor, Serologically defined colon cancer antigen 1.
What is the protein family that this protein belongs to?
Belongs to the NEMF family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: PSB9_ONCMY
Sequence: MLDESLEPGWLSEEVKTGTTIIAIEFDGGVVLGSDSRVSAGETVVNRVMNKLSLLHDKIYCALSGSAADAQTIAEMVNYQLDVHSIEVGEDPQVRSAATLVKNISYKYKEDLSAHLIVAGWDKRGGGQVYVTLNGLLSRQPFAVGGSGSSYVYGFVDAEYRKAMSKEDCQQFVVNTLSLAMSRDGSSGGVAYLVTIDEKGAEEKCILGNELPTFYDQ
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.  This subunit is involved in antigen processing to generate class I binding peptides (By similarity).
What are the official names of this protein?
Proteasome subunit beta type-9, Low molecular mass protein 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MEP1_SOYBN
Sequence: MTLRNHQELLVALATLYFLATSLPSVSAHGPYAWDGEATYKFTTYHPGQNYKGLSNVKNYFHHLGYIPNAPHFDDNFDDTLVSAIKTYQKNYNLNVTGKFDINTLKQIMTPRCGVPDIIINTNKTTSFGMISDYTFFKDMPRWQAGTTQLTYAFSPEPRLDDTFKSAIARAFSKWTPVVNIAFQETTSYETANIKILFASKNHGDPYPFDGPGGILGHAFAPTDGRCHFDADEYWVASGDVTKSPVTSAFDLESVAVHEIGHLLGLGHSSDLRAIMYPSIPPRTRKVNLAQDDIDGIRKLYGINP
What is the function of this protein?
Matrix metalloproteinases (MMPs) or matrixins may play a role in the degradation and remodeling of the extracellular matrix (ECM) during development or in response to stresses.
What are the official names of this protein?
Metalloendoproteinase 1, SMEP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family. Matrix metalloproteinases (MMPs) subfamily.
Protein: GLP3L_RAT
Sequence: MTTLTHRTRRTEVSKSCEKKIESEEDTNQERSPDNEDPGDSKDIRLTLMEEVLLLGLKDKEGYTSFWNDCISSGLRGGILIELAMRGRIYLEPPTMRKKRLLDRKVLLKSDSPTGDVLLDETLKHIKATEPTETVQTWIELLTGETWNPFKLQYQLRNVRERIAKNLVEKGILTTEKQNFLLFDMTTHPVTNTTEKQRLMKKLQDSVLERWVNDPQRMDRRTLALLVLAHSSDVLENVFSCLTDDKYDVAMNRTKDLVELDPEVEGTKHNATEMIWAVLAAFNKS
What is the function of this protein?
Phosphatidylinositol-4-phosphate-binding protein that may antagonize the action of GOLPH3 which is required for the process of vesicle budding at the Golgi and anterograde transport to the plasma membrane.
What are the official names of this protein?
Golgi phosphoprotein 3-like.
What is the protein family that this protein belongs to?
Belongs to the GOLPH3/VPS74 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein; Cytoplasmic side. Note=Phosphatidylinositol 4-phosphate (PtdIns4P)- binding mediates recruitment to Golgi membranes.
Protein: CAPSD_FBNY2
Sequence: MASKWNWSGTKGRRTPRRPYGRPYKSSVPTTRVVVHQSAVLKKDEVVGTEIKPEGDVARYKMKKVMLTCTLRMAPGELVNYLIVKCNSPISSWSAAFTSPALLVKESCQDMITIIAKGKVESTGVAGTDCTKSFNRFIKLGAGITQTQHLYVVLYTSVALKAVLEHRVYVEV
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the nanoviridae capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: BIOD_AERHH
Sequence: MVKSFFVTGTDTDVGKTLVARTLLLEFAAHGLRCAGYKPISAGCARTPDGLRNLDAVLLQEAASLPLPYDLVNPYAYEPPIAPHIAASEARDAITLKGLSDGLRQIEQAGAELVVVEGAGGWFLPLDRKHLLSDWVKQENMPVIMVVGAKLGCLNHALLTFAAIRNNNLPVAGWVINRLHGSMSHYQENLDTLRGLLPAPFLGEIPFVNNPLEADLRGRLDISPLL
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_SALDC
Sequence: MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNEKLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIDEAVEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GNAS3_HUMAN
Sequence: MDRRSRAQQWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALATSNARAQQRAAAQQRRSFLNAHHRSGAQVFPESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETDFETEPETAPTTEPETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGEELKPEDKDPRDPEESKEPKEEKQRRRCKPKKPTRRDASPESPSKKGPIPIRRH
What are the official names of this protein?
Neuroendocrine secretory protein 55, NESP55.
What is the protein family that this protein belongs to?
Belongs to the NESP55 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Secreted. Note=Neuroendocrine secretory granules.
Protein: OLSG_SINAD
Sequence: MKDFFLFLGKFFKHGTAIASLAPSSPWLSRTTVRNIPWENARVVVELGAGTGPITKVIADRVHPDCRVIVLERDPDFARLLRERFANRANFDVVEGDVRDLTQILQQRGIEQADFVVSGLPVPSFPKELQRDLFRVVKQVLAPSGTFNQITEMPWVYQRFYRRFFDEVTFVFEPRNLPPAGAYFCRGVKESF
What is the function of this protein?
Catalyzes the 3-fold methylation of ornithine lipids.  Forms ornithine lipids that are mono-, di-, and trimethylated on the delta-nitrogen of the ornithine head group.
What are the official names of this protein?
Ornithine lipid N-methyltransferase, OL N-methyltransferase, Ornithine lipid synthesis G.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: COPP_THEVO
Sequence: MITVVGGTFSKLHKGHKALLEKAIETGNEIVIGLTSDEYVKRNKVYPAIPYKERYRNLYNYMVKKTNKFRIRPIDDRNGNAPYERDYEIIVVSPETYQRSLKINEIRIQNGLPPLKIIRVPYVLAEDLFPISSTRIINGEIDGNGRRLKPVKVAIATNNSAKLKATNDFFHKLMKNFDVIQNTDYKLETQQPFGEVTMNMATKRAMQSLGDNDYAIGIESGIVYERFSRKYFDFHYCVVIDRFGNVTRGSSSGFEVPDRIIDLIKRDMSFSQAYGKVIDTNGIDDSTGIVGKISNGRVRRYDLIMECIRNAFIPRFDPDFYDTTYTPP
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Bifunctional phosphopantetheine adenylyltransferase/NTP phosphatase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the YjjX NTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIF3L_RAT
Sequence: MLSSAHVVPTSVRRAPSWICSSSRSFMDLKALLSSLNDFASLSFAESWDNVGLLVEPSPPHTVNTLFLTNDLTEEVMEEALQKKADLILSYHPPIFRPMKHITWKTWKERLVIRALENRVAIYSPHTAYDAAPQGVNSWLAKGLGTCTTRPIHPSKAPNYPTEGTHRLEFSANHSQDLDKVMSAVKGVGGVSVTSFPARCDGEEQTRVSLNCTQKALMQVLAFLSQDRQLYQKTEILSLEKPLLLHTGMGRLCTLDESVSLATMIERIKRHLKLPHLRLALGVGRTLESPVKVVALCAGSGGSVLQGVEADLYLTGEMSHHDVLDAASKGINVILCEHSNTERGFLSDLQEMLGVHLENKINIILSETDRDPLRVV
What is the function of this protein?
May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
What are the official names of this protein?
NIF3-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Interaction with COPS2 may regulate localization to the nucleus.
Protein: UVRC_SALA4
Sequence: MSEIFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQHIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYRNRSRPCLQYQIGRCLGPCVAGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLIARMEKASQDLAFEEAARIRDQIQAVRRVTERQFVSNAGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELGEVVETFVGQFYLQGSQMRTLPGEILLDFNLSDKTLLADSLSELAGRRIHVQTKPRGDRARYLKLARTNAATALITKLSQQSTITQRLTALAAVLKLPAIKRMECFDISHTMGEQTVASCVVFDANGPLRAEYRRYNIAGITPGDDYAAMNQVLRRRYGKAIEESKIPDVILIDGGKGQLAQAKAVFAELDVPWDKHHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSTLETIEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLMA_CROS8
Sequence: MAEKQTAKRNRREEILQSLAQMLESSDGSQRITTAKLAASVGVSEAALYRHFPSKTRMFDSLIEFIEDSLITRINLILKDEKETLNRLRLIVLLILGFGERNPGLTRILTGHALMFEQDRLQGRINQLFERIEAQLRQVLREKKMREGEGYATDEALLASQLLAFCEGMLSRFVRSEFRYSPTADFEARWPLLAAQLQ
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: Y2365_PECAS
Sequence: MTERPFWQQKTLSEMSDDEWESLCDGCGQCCLHKLIDEDTEEIYFTNVACNQLNIKSCQCRNYEKRFEYEPDCIKLTRENLLTFNWLPATCAYRLVHEREDLPQWHPLVCGTKTEMHRERISVRHIAVRESEVVDWQDHILNKPGWAR
What are the official names of this protein?
UPF0260 protein ECA2365.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: YHV2_LACHE
Sequence: MDIHDYVELIALAFWVISVVSVGILSHVHFKNKRLEQFRITADDLMKNYVGLYNKESLASDQKINRIVNAVVDGLEAKGFKVEDQDVKDIFAKVAKIINENSSK
What are the official names of this protein?
Uncharacterized 11.8 kDa protein in hlv 5'region, ORF2.
Protein: PGK_METFV
Sequence: MFKFYTMDDFDYSGSRVLVRVDINSPVDPHTGRILDDTRMRLHSKTLKELVDENAKVAILAHQSRPGKRDFTTMEEHSKVLSNILDMPVTYVEDIFGCAARESIRNMENGDIILLENVRFYSEEVLKRDPKVQAETHLVRKLSSVVDYYINDAFAAAHRSQPSLVGFPLKLPSAAGRLMEREVKTLYKIIKNVEKPCVYILGGVKIDDSIMIMKNILKNGSADYILTSGLVANVFLEASGIDIKEKNRKILYRKNYKKFIKMAKKLKDKYGEKILTPVDVAINKNGKRIDVPIDDIPNFPIYDIGMETIKIYAEKIREAKTIFANGPAGVFEEQQFSIGTEDLLNAIASSNAFSVIAGGHLAAAAEKMGISNKINHISSGGGACIAFLSGEELPAIKVLEEARKRSDKYI
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDT4L_HUMAN
Sequence: MVATGSLSSKNPASISELLDCGYHPESLLSDFDYWDYVVPEPNLNEVIFEESTCQNLVKMLENCLSKSKQTKLGCSKVLVPEKLTQRIAQDVLRLSSTEPCGLRGCVMHVNLEIENVCKKLDRIVCDSSVVPTFELTLVFKQENCSWTSFRDFFFSRGRFSSGFRRTLILSSGFRLVKKKLYSLIGTTVIEGS
What is the function of this protein?
Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1.
What are the official names of this protein?
DNA damage-inducible transcript 4-like protein, HIF-1 responsive protein RTP801-like, Protein regulated in development and DNA damage response 2, REDD-2.
What is the protein family that this protein belongs to?
Belongs to the DDIT4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_RICAE
Sequence: MLNIKWIRENKELFDEKLSQRFIEPMSSKIAMLDGKKRKITSLIQEFQHARKVKSKILGNMASKSGEEFEGLQRDVKHINEKLEALEQELNNNNELNELLNMFPNIPDEEVPYGMDESMNKLVRTYGETNPNALNKQHFELGIKLNLMDFEQTAKISGTRFVTLKGDLAKLERALINFMIDVHTKEWDFFEISPPVLVRDNAMYNAGQLPKFAEESFATTNGYRLIPTAEVSLVNMVADTIIPREKLPIRYVAYTPCFRSEAGSSGKDTRGMIRLHQFGKVELVSITTPEESTNEHEYITNASETILQKLNLPYRVMLLCTGDMGFAAKKTYDIEIWLPGQKQYREIASCSNCGDFQARRMKARYKEFGSNETTLVHTLNASGLPIGRTMVAILENYQNEDGSITIPDVLINYMGGLQKIIAYSE
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBT_ECOL6
Sequence: MQILADLLNTIPAINSAAMSRAQRHVDGLLKPVGSLGKLEALAIQLAGMPGLNGIPHVGKKAVLVMCADHGVWEEGVAISPKEVTAIQAENMTRGTTGVCVLAAQAGANVHVIDVGIDTAEPIPGLINMRVARGSGNIASAPAMSRRQAEKLLLDVICYTRELAKNGVTLFGVGELGMANTTPAAAIVSTITGRDPEEVVGIGANLPTDKLANKIDVVRRAITLNQPNPQDGVDVLAKVGGFDLVGIAGVMLGAASCGLPVLLDGFLSYAAALAACQMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNMDMRLGEGSGAALAMSIIEAACAIYNNMGELAASNIVLPGNTTSDLNS
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.