PharMolix/UniProtQA huggingface dataset:
Protein: LIPA_SALEP
Sequence: MSKPIVMERGVKYRDADKMALIPVKNVVTERDALLRKPEWMKIKLPADSTRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPVAPDAEEPQKLAQTIADMALRYVVITSVDRDDLRDGGAQHFADCITAIRAKSPEIKIETLVPDFRGRMDRALDILNATPPDVFNHNLENVPRIYRQVRPGADYNWSLKLLERFKEAHPEIPTKSGLMVGLGETNAEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQRYVSPEEFDEMKAEALAMGFTHAACGPFVRSSYHADLQAKGMEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS5_DESVM
Sequence: MLAILDYKAGNQTSVRRALDHLGIPCVITADPAVIAGAHGVIFPGVGAAGQAMNELLTTGLDKVLKDQVQAGKPLLGICVGCQIMLDYSQENDTKALGIVPGECRLFNAAWTEEDGTPIRVPHMGWNSIVQKRPCELLKGIEPEAEFYFVHSYYPAPPESYVIATCTYGEEFCAIHGGPGLWAVQFHPEKSGRPGLALLRNFYAYCKEASRA
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDST1_XENTR
Sequence: MSLSLKTRRFGRPVRPQLVLLLLFALCLLSVFISAYYLYGWKRGLEPSGSEAQSPDCDEPKISPSRLLPMKPLKPVDSSRTDPLVLVFVESLYSQLGQEIVAILESSRFKYRTEIAPGKGDMPTLTDKDRGRFALIVYENILKYVNLDAWNRELLDKYCVEYGVGIIGFFKANENSLLSAQLKGFPLYLHSNLGLKDCSINPKSPLLYITRPNQVEKGDLPGEDWTVFQSNHSTYEPVLLAKTKSAESIPHLSVDAALHTTVVQDLGLHDGIQRVLFGNNLNFWLHKLVFVDAVSFLTGKRLSLPLNRYVLVDIDDIFVGKEGTRMKVEDVKALYDTQMELRTHIPNFTFNLGFSGKFFHTGTDAEDEGDDLLLSYVKQFWWFPHMWSHMQPHLFHNQSVLAEQMALNRKFAVEHGIPTDMGYAVAPHHSGVYPVHVQLYEAWKQIWGIKVTSTEEYPHLKPARYRRGFVHNGIMVLPRQTCGLFTHTIFYNEYPGGPVELDKIINGGELFLTVLLNPISIFMTHLSNYGNDRLGLYTFKHLVQFLNTWTNLKLETLPPVQLAHKYFQIFPEEKDPLWQDPCEDKRHKDIWSKEKTCDRFPKLLIIGPQKTGTTALYLFLGMHSDLSSNYPSSETFEEIQFFNGQNYHKGIDWFMEFFPIPSNTTSDFYFEKSANYFDSELAPRRVAALLPKAKIITILINPADRAYSWYQHQRAHDDPVAMKYTFQEVITAGPEAPQRLRALQNRCLVPGWYSTHIERWMNHFHANQILVLDGKLLRTEPANVMETVQKFLGVTNAMDYHKTLAFDPKKGFWCQLLDGGRTKCLGKSKGRKYPDMDSDSRSFLMDYYRDHNIELSKLLYKMGQTLPTWLREELQSTR
What is the function of this protein?
Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate.  Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis.  Plays a role in determining the extent and pattern of sulfation of heparan sulfate.
What are the official names of this protein?
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1, Glucosaminyl N-deacetylase/N-sulfotransferase 1, NDST-1.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family. NDST subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type II membrane protein.
Protein: RS6_LISMC
Sequence: MARKYEIMYIIRPNIEEDEKKAVVERFDGILTENGAEIIESKEWGKRRLAYEINDYRDGFYHIVKLNADKADSINEFDRLAKISDDIIRHMVIKEEA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: BIOF_SERP5
Sequence: MSWQQRIEQALEERQQSAAYRRRQVNQGGNGRYIQLNGEHYLNFSGNDYLGLSQNAQVIAAWQQGAQQYGVGSGGSGHVTGFSTAHQVLEQQLADWLGYPRALLFISGYAANQALLAALMQAEDRILADRLSHASLLEAAAHSPAQLRRFRHNQPQALADLLAKPCDGQILAVTEGVFSMDGDSAPLAELHRLTRAAGAWLMVDDAHGIGVHGEQGRGSCWQQGVRPELLVVTFGKAFGLSGAAVLCDEPTAEYLLQFARHLIYSTAMPPAQASALQAALHCIRQGDELRARLQDNIQRFRQGAAQLSLTLTESVTAIQPLLVGDNQRALDLAQSLREQGLWVSAIRPPTVPPGGARLRITLTAAHQPQDIDRLLEVLHDVSV
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: MEU15_SCHPO
Sequence: MEETLPSYEAASGAANLQEVKPQVLPLEEIKKIYKISYWWLCSIALIQTWWVLLGLLPIFFALEHYEVPYKWIFIIEMLYYELYLTLYVCWCYKLRSDFWNEAAKNRPNEERLSALGGWDFLRIPKKRVLVLRDAQSEKKQNNADASNLV
What are the official names of this protein?
Meiotic expression up-regulated protein 15.
Protein: APE2_SULTO
Sequence: MVSIDKYEIFLDFDFKNLIYKGYEKIYLSTDNEVVLDSVGLNIVSVKTEGKSVPFKISDSQIFIQTGKFDGVLEIEFEGKVKERGLVGIYKAPYDHSYIITTQFESVHAREFIPCIDHPAFKARFKLSVKVDKDLDVISNMPIEDVREEGDKKIVTFQETPRMSTYLLYLGIGKFEEIKDKLGEVDIIVATVPGRISKGKFALDVAKKVIEYYEDYFGIKYQLPKEHLIAIPEFAFGAMENWGAITFRETALLADESSSVQQKMRVASVVAHELAHQWFGDLVTMKWWDDLWLNESFATFMSHKAIAELYKEWDFWGTFINSETSGALFRDSLTTTHPIEAHVTSPEEIEQLFDDISYGKGASILRMIEAYLGDEDFRKGIQIYLNTYKYSNATGSDFWNSLEKGSGKPVSEIVKDWITKDGYPVVYVSVNGSKINLEQERFYLKGNGKNAVYKVPLTLEVNGRKITYLLEKEKDSIDIGSDIKSIKVNIDRTGFYRVYYNDLSLVFNSKLSHLDKWGLFNDYFNFFLAGRVNYTTYESIAKQFMKDDNYLVVDELVSELYYLWRVNRDKYKLLYEVLPYQVKRFSKRKDELSRRTYSYLLSTFAFVDEKFASGLAVAFEKYDTLDPNVKEAVAIAYAVTYGEDAYDELLNKYRSEKFDEEKTRLLYGLLSFREPYLVVNTMSLALTGEIKRQDVARILPYASYNPYSRLALWKWLKTHMEFLRSIYAGTAILGRTLRSVIPFLGLNNAEVVEYFTTNRFPEMEVEIKSGLEILDSLRRII
What are the official names of this protein?
Probable aminopeptidase 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_GEOUR
Sequence: MALRVYNTLTGTKEDFVPIEPGKVKMYVCGVTVYDHCHIGHARANVVFDVIYRYLRSLGLEVNYVRNYTDIDDKIINRANREGVAYDAISERFIKEFDRDMAQLGLLLPTSQPKATEHIPEIITLVQTLIDKGFAYQMGGDVNFCVEKFDPYLKLSKRNLEDMQAGARIEVDERKRHPMDFVLWKEAKPGEPFWESPWGKGRPGWHIECSAMSMKYLGETFDIHGGGKDLVFPHHENEIAQSEAASGKPFVKYWLHNGFVNINSEKMSKSLGNFFTIKEVLDKYDSEVLRFFLLSAHYRSPLDFSDQNLTEAETGMERIYKALVAIDETLASNPATGGEEIDASSLGEAERELFDKSGSLPLRFREAMDDDFNTALAMGHIFDLVRCVNRVLSEAKERSNTLSALCAQVKANIGKIADVLGIFTSEPASLLTRLKDRKASELDISVEEIERLITERAAARKAKDFKRSDEIRDFLLGKNIVLLDSAQGTSWSVK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_SACD2
Sequence: MKFSGSHILSVEQFERADIERIFAVADSMEPYALRQKVTRVLEGAILGNMFFEPSTRTRVSFGCAFNLLGGEVRETTGFKSSAIAKGESLYDTARVLSGYSDVICMRHPQEGSVAEFAQASRVPVINGGDGANEHPSQALLDLYTIQKELRDKGRSLDGLRIAMIGDLKHGRTVHSLMRLLGLFANLQVVLVSPEELAMPEEYVELLRGLGHRVDVSSDLANSIGHVDIVYSTRIQEERFGSKEEADLYRGRFRLNQAIYTQFCEPNTVIMHPLPRDSRSDANELDNDLNQNPNLAIFRQTDNGILVRMALFALILDVADQVDKFSRPVNWYHSRTF
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: NU1M_ZAGBR
Sequence: ILLAVAFLTLIERKILGYMQFRKGPNIVGPHGLLQPIADAVKLFIKEPLRPMTSSIYMFILAPILALSLALTIWVPLPMPLPLIDLNLGLLFVLSVSGLSVYSILWSGWASNSKYALTGALRAVAQTISYEVTLAIILLSIMLINGSFTLTTLNLTQEFMWLVVPTWPLMLTRFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFAMFFLAEYANIIIMNALTVILFFGAYHLIFLPELSTINFMIKTMMLTSLFLWIRASYPRFRYDQLMHLLWKNFLPITLVTCLWFIMLPLALSWIP
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RNZ_METJA
Sequence: MIIMKLIFLGTGAAVPSKNRNHIGIAFKFGGEVFLFDCGENIQRQMLFTEVSPMKINHIFITHLHGDHILGIPGLLQSMGFFGREKELKIFGPEGTKEIIENSLKLGTHYIEFPIKVYEIYTKEPITIYKEENYEIIAYPTEHGIPSYAYIFKEIKKPRLDIEKAKKLGVKIGPDLKKLKNGEAVKNIYGEIIKPEYVLLPPKKGFCLAYSGDTLPLEDFGKYLKELGCDVLIHEATFDDSAKDAAKENMHSTIGDAVNIAKLANVKALILTHISARYDKEEYFNLYKMNVKQYNESFKIIISEDLKSYDIKKDLLG
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: FOLB_STAAR
Sequence: MQDTIFLKGMRFYGYHGALSAENEIGQIFKVDVTLKVDLSEAGRTDNVIDTVHYGEVFEEVKSIMEGKAVNLLEHLAERIANRINSQYNRVMETKVRITKENPPIPGHYDGVGIEIVRENK
What is the function of this protein?
Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.  Can also catalyze the epimerization of carbon 2' of dihydroneopterin to dihydromonapterin.
What are the official names of this protein?
Dihydroneopterin aldolase, DHNA, 7,8-dihydroneopterin 2'-epimerase, 7,8-dihydroneopterin aldolase, 7,8-dihydroneopterin epimerase, Dihydroneopterin epimerase.
What is the protein family that this protein belongs to?
Belongs to the DHNA family.
Protein: RL22_BACAC
Sequence: MQAKAVARTVRIAPRKVRLVVDLIRGKQVGEAIAILNHTPKTASPVVEKVLKSAIANAEHNYEMDINSLVVEKVFVDEGPTLKRFRPRAMGRASQINKRTSHITVVVSEKKEG
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: LIPA_PLAVS
Sequence: MHVLTPSLYIYAFFIVCVRLKCGRSKRVANAKHATYDMPPKGLRVRDMLEKTAQQNCNQRKRGKCRKFFFLWKMDKMGDTHLGGQANGRKNLLRSESATDEASLGGNPLKEKLKESPANWGKDKQEEQQSTDRLPLPKVGNKMPEKKPDWFHVPAPTGKKYNELKADLKKLKLHTVCEEAQCPNIGECWNIGTATIMLLGDTCTRGCKFCSIKTSSKPLPPDANEPFNTAKAICEWDINYVVLTSVDRDDLPDGGASHFAKTIELIKFSRPEILIECLVSDFQGNVDSIRKLANSGMEVYAHNIETVRRLQKFVRDRRANYEQSLWVLKTAKEINPLLYTKTSIMLGLGETKQEVLQAMADVRQNNIDVITFGQYLRPTKNHLNVVEYVSPQMFDYYKEEGMKMGFKYIASGPLVRSSYKAGEYFMKNLVEQRRGVKLHAEG
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, apicoplast, Lipoate synthase, LS, Lip-syn, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Plastid, apicoplast.
Protein: SHY1_YEAST
Sequence: MSLLGARSTYRWFSIAASIPTKNAIGKSTYLLASRNQQYRGIITSTVDWKPIKTGKSPNDDSRRERSFGKKIVLGLMFAMPIISFYLGTWQVRRLKWKTKLIAACETKLTYEPIPLPKSFTPDMCEDWEYRKVILTGHFLHNEEMFVGPRKKNGEKGYFLFTPFIRDDTGEKVLIERGWISEEKVAPDSRNLHHLSLPQEEHLKVVCLVRPPKKRGSLQWAKKDPNSRLWQVPDIYDMARSSGCTPIQFQALYDMKDHPIIEEHTRNEASQNNSTSSLWKFWKREPTTAVNGTQAVDNNTSKPRSRQEMPTDQTIEFDERQFIKAGVPIGRKPTIDLKNNHLQYLVTWYGLSFLSTIFLIVALRKAKRGGVVSQDQLMKEKLKHSRKYM
What is the function of this protein?
Required for efficient assembly of cytochrome c oxidase in the mitochondrial inner membrane.  Involved in a step that couples MSS51-COX14-dependent regulation of COX1 translation to early steps of cytochrome c oxidase assembly.
What are the official names of this protein?
Cytochrome oxidase assembly protein SHY1, SURF1 homolog of Yeast, SURF1-like protein.
What is the protein family that this protein belongs to?
Belongs to the SURF1 family.
Protein: DCUP_FRATN
Sequence: MRKLFLDAFGEKKLDKPPVWIMRQAGRYLPEYRAVRAKFDNFMDMCRNADACCEVALHPLQRYDLDAAIVFSDILTIPEAMGMDLKFIKGTGPVFSEPIQSQKDLDKLKSIEDSIGSLDYVYNAVKTTSSTINVPLIGFTGSPWTLAAYMIEGSGSKQFNKLRKMMYANPQLMHSLLQRLADITIIYLLEQVKAGASCVMIFDTWGGILPLEHYKNFSLKYMEYIAKNVKQKINIPIVFFTKGGSNFFEEIKDKSCDGVGVDWSVTLKQARHRIGVGKVLQGNFDPAFLYGSKQSIRETVRANIEFIQSDKLNNYIVNLGHGIYPDIDPDSVRVMIDAIREFSA
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGME1_HUMAN
Sequence: MKMKLFQTICRQLRSSKFSVESAALVAFSTSSYSCGRKKKVNPYEEVDQEKYSNLVQSVLSSRGVAQTPGSVEEDALLCGPVSKHKLPNQGEDRRVPQNWFPIFNPERSDKPNASDPSVPLKIPLQRNVIPSVTRVLQQTMTKQQVFLLERWKQRMILELGEDGFKEYTSNVFLQGKRFHEALESILSPQETLKERDENLLKSGYIESVQHILKDVSGVRALESAVQHETLNYIGLLDCVAEYQGKLCVIDWKTSEKPKPFIQSTFDNPLQVVAYMGAMNHDTNYSFQVQCGLIVVAYKDGSPAHPHFMDAELCSQYWTKWLLRLEEYTEKKKNQNIQKPEYSE
What is the function of this protein?
Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance.  Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates.  Necessary for maintenance of proper 7S DNA levels.  Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair.  Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells.
What are the official names of this protein?
Mitochondrial genome maintenance exonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the MGME1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YTH1_USTMA
Sequence: MNAPLTLHRSGAGPSSYSSHRPLITQQRLVGASSSIPSQFIHNEFSFEQYIKDHLNVKLDNDAQICPDYSERLQCPRGASCPRRHVRPSHLNFLPAGSTALRDPNKRTVCKHWLRGLCKKDDQCDYLHEYDMRRIPECRFYATFGFCNSGDDCLYLHVDPAIKRRECERYNRGFCPKGPLCTKKHVRRVACPLYLAGFCPEGLDCPRGHVKSTPASSASRSNSPIQTHRPLTAAEAFGTGTGRGDEYGDGAGMRNQRAPAGRYGLPSGGAAGGAGAADIGASRGGMGYANNMQRRPNNVFGAPAQGAQEGGRGWRKDLSEVLCFKCGEMGHFANMCPNPALPGNRGGVERGPGGQARQARDRPRPY
What is the function of this protein?
Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
What are the official names of this protein?
mRNA 3'-end-processing protein YTH1.
What is the protein family that this protein belongs to?
Belongs to the CPSF4/YTH1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS11_CERSK
Sequence: MARDKTRMKRKERKNIAAGVAHVNSSFNNTKILISDVQGNAISWSSAGTMGFKGSRKSTPYAAQMAAEDAAKKAQDHGMKTIEVEVQGPGSGRESALRALAAAGLNITSIRDVTPMAHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: CH60_ANAMF
Sequence: MANVVVTGEALDKSIREVVRILEDAVGCTAGPKGLTVAISKPYGSPEITKDGYKVMKSIKPEEPLAVAIANIITQSASQCNDKVGDGTTTCSILTAKVIEEVSRAKAAGADTISIKNGILKAKEAVLTALLSMKREVASEDEIAQVATISANGDKNIGGKIAQCVREVGKDGVITVEESKGFKDLEVERTDGMQFDRGYLSPYFVTNAEKMLVEFENPYIFLTEKKINLVQSILPVLENVARSGRPLLIIAEDVEGEALSTLVLNKLRGGLQVAAVKAPGFGDRRKDMLGDIAVIAGAKYVVNDELAVKVEDITLDDLGTAKTVRITKDTTTIIGSVDSNADSITSRISQIKSQIEVSSSDYDKEKLKERLAKLSGGVAVLKVGGSSEVEVKERKDRVEDALHATRAAVEEGVVPGGGAALLYTLASLDGIKGKNDDEQLGINIIKRAVCAPIKRIIKNSGSEEAPCVIQHLMKQNDKELIFNVDTMNYANAFASGVMDPLKVVRIAFDLAVSLAAVFMTLNAVVVDVPSKEDTAGGGAAGGMGGMGGF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCADS_STRCL
Sequence: MSTRPVEGSAIWDVLSPHSPHAAAADGKTLVWVEAGELCGHDTAESANLARIRPGLLAAFCHPKATEDDLTLITKWMAWLFLLDDRIDESDLGRDADLLDGHLQDLQGVALGIRTASGPMSRALEEIITQASAGMGDAWQLRFRRNISDYLLACVWQAAHRQAGEFPDPEVFPHWRRAFGAIMPSFDLIERTDGGALPSCVYYSRPYQSLLTAAADLVCWTNDLMTVDKEAAHGDLHNLVLVTEHDRHQDRRTASAAVSAACEQRMRAHTSARRDLTGLTAALGLPDTVRTHADDCAASLLVWVRGHLEWGLETPRYRPGTTGTGTD
What is the function of this protein?
Catalyzes the conversion of (2E,6E)-farnesyl diphosphate into (-)-delta-cadinene.  Cyclization mechanism involves an intermediate nerolidyl diphosphate leading to a helminthogermacradienyl cation.
What are the official names of this protein?
(-)-delta-cadinene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: RL14_RHILW
Sequence: MIQMQTNLDVADNSGARRVMCIKVLGGSKRKYASIGDVIVVSIKEAIPRGRVKKGDVMKAVVVRTAKDIRRPDGSVIRFDTNAAVLIDNKKEPIGTRIFGPVPRELRAKNHMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: EFP_TRIV2
Sequence: MISSNDFRPGVSIVLDGSVWRVIDFLHVKPGKGSAFVRTTLKNVQSGKVLEKTFRAGETVPQATLEKITMQHTYKEGDEFVFMDMESYEEGRLSASQIGDRVKYLKEGMEVNVIRWGEQVLEVELANSVVLEVIQTDPGVKGDTATGGTKPAIVETGATVMVPLFISQGERIKIDTRDDKYLGRE
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H6ST3_MOUSE
Sequence: MDERFNKWLLTPVLTLLFVVIMYQYVSPSCTSSCTNFGEQLRSGEARPPAVPSPARRAQAPLDEWERRPQLPPPPRGPPEGSRGVAAPEDEDEDPGDPEEEEEEEEEEPDPEAPENGSLPRFVPRFNFTLKDLTRFVDFNIKGRDVIVFLHIQKTGGTTFGRHLVKNIRLEQPCSCKAGQKKCTCHRPGKKETWLFSRFSTGWSCGLHADWTELTNCVPAIMEKKDCPRNHSHTRNFYYITMLRDPVSRYLSEWKHVQRGATWKTSLHMCDGRSPTPDELPTCYPGDDWSGVSLREFMDCSYNLANNRQVRMLADLSLVGCYNLTFMNESERNTILLQSAKNNLKNMAFFGLTEFQRKTQFLFERTFNLKFISPFTQFNITRASNVDINDGARQHIEELNFLDMQLYEYAKDLFQQRYHHTKQLEHQRDRQKRREERRLQREHRAHRWPKEDRAMEGTVTEDYNSQVVRW
What is the function of this protein?
6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
What are the official names of this protein?
Heparan-sulfate 6-O-sulfotransferase 3, HS6ST-3, mHS6ST-3.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 6 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: MZM1_AJECG
Sequence: MAATTAPNPLTAYRFLLRATRIAFQGDFTTLHAARAEARKQFDQHRKQGVDTPMRIQHAMETAEILRTNVVQGVKISGAGEEAERYASILVMRRFRGEYEGEDERREKEEAMRELRIHEHIERGDNDSIKTAGKNERVKVAVGKACSNTQSSE
What is the function of this protein?
Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex.  Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.  Modulates the mitochondrial matrix zinc pool (By similarity).
What are the official names of this protein?
Mitochondrial zinc maintenance protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. MZM1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: APIBP_AGRRK
Sequence: MKLTRRLTLAAFASVLALGTAAPAFSADLIAIITPAHDNPFFKAEAVGAEAKAKELGYDTLVMSHDDDANKQSEVIDTAIGRGAKAIILDNAGADATVAAIKKAKDAGIPSFLIDREINVTGIAVAQIVSNNYQGAQLGAQEFVKLMGEKGNYAELVGREADTNAGIRSQGYHDVIDDYPDLKLVAKQSANWSQTEAYAKMETILQANPDIKGVISGNDTMAMGAIAALQAAGRKDVIVVGFDGSNDVRDSIKAGGIKATVMQPAYAQAQIAVQQADAYIKNKTVPKDEKQLMDCVLINADNADKLETFALKN
What is the function of this protein?
Part of an ABC transporter complex involved in D-apiose import.
What are the official names of this protein?
D-apiose import binding protein, D-apiose binding SBP.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 2 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ZIPA_YERPE
Sequence: MMQDLRLILIVVGAIAIIALLLHGLWTSRKERSSLFRDRPVKRTKQERVETPIESLDEGVGEVRVRTSHPQEKPSFNHLDDDDDEVPVIQHAETKSAQVKTASRQAPFASVQTDYDDPLLGGLSAEQPPHDLSRDPLLGKADESYSQPQHAEPPHVEKPAHQVAPQQHVESQQEPVAPAPEAKPQKLKETVLVLHVAAHHGGVIGGEVLLQSVLQSGFQFGEMGIFHRHLSPAGSGPVLFSLANMVKPGSFDPDTMSDFSTPGVSMFMMVPSYGDANQNFKLMLQSAQRIADDVGGVVLDDERRMMTPQKLESYKARIREVLDANTIA
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: ACT_AJECG
Sequence: MEEEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHHGIMIGMGQKDSYVGDEAQSKRGILTLRYPIEHGVVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPINPKSNREKMTQIVFETFNAPAFYVSIQAVLSLYASGRTTGIVLDSGDGVTHVVPIYEGFALPHAISRIDMAGRDLTNYLMKILAERGYSFSTTAEREIVRDIKEKLCYVALDFQQEIQTASQSSSLEKSYELPDGQVITIGNERFRAPEALFQPSVLGLESGGIHATTYNAIMKCDVDVRKDLYGNIVMSGGTTMYPGISDRMQKEITALAPSSMKVKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.