PharMolix/UniProtQA huggingface dataset:
Protein: OBLA_ASPCL
Sequence: MACKYSTLIDSSLYDREGLCPGIDLRRHVAGELEEVGAFRAQEDWRRLVGPLPKPYAGLLGPDFSFITGAVPECHPDRMEIVAYALEFGFMHDDVIDTDVNHASLDEVGHTLDQSRTGKIEDKGSDGKRQMVTQIIREMMAIDPERAMTVAKSWASGVRHSSRRKEDTNFKALEQYIPYRALDVGYMLWHGLVTFGCAITIPNEEEEEAKRLIIPALVQASLLNDLFSFEKEKNDANVQNAVLIVMNEHGCSEEEARDILKKRIRLECANYLRNVKETNARADVSDELKRYINVMQYTLSGNAAWSTNCPRYNGPTKFNELQLLRSEHGLAKYPSRWSQENRTSGLVEGDCHESKPNELKRKRNGVSVDDEMRTNGTNGAKKPAHVSQPSTDSIVLEDMVQLARTCDLPDLSDTVILQPYRYLTSLPSKGFRDQAIDSINKWLKVPPKSVKMIKDVVKMLHSASLMLDDLEDNSPLRRGKPSTHSIYGMAQTVNSATYQYITATDITAQLQNSETFHIFVEELQQLHVGQSYDLYWTHNTLCPTIAEYLKMVDMKTGGLFRMLTRMMIAESPVVDKVPNSDMNLFSCLIGRFFQIRDDYQNLASADYAKAKGFAEDLDEGKYSFTLIHCIQTLESKPELAGEMMQLRAFLMKRRHEGKLSQEAKQEVLVTMKKTESLQYTLSVLRELHSELEKEVENLEAKFGEENFTLRVMLELLKV
What is the function of this protein?
Bifunctional sesterterpene synthase; part of the gene cluster that mediates the biosynthesis of the sesterterpenes ophiobolins, fungal phytotoxins with potential anti-cancer activities (PubMed:23324037, PubMed:27116000, PubMed:28362483).  The first step of the pathway is performed by the sesterterpene synthase oblA that possesses both prenyl transferase and terpene cyclase activity, converting isopentenyl diphosphate and dimethylallyl diphosphate into geranylfarnesyl diphosphate (GFPP) and further converting GFPP into ophiobolin F, respectively (PubMed:23324037).  Other sesterterpenoids (C(25) terpenoids) are found as minor products of oblA (PubMed:23324037).  It is expected that ophiobolin F is then oxidized to ophiobolin A via ophiobolin C and ophiobolin B intermediates by the combined action of the cytochrome P450 monooxygenase oblB and the FAD-dependent oxidoreductase oblC (Probable).  Although oblB catalyzes multistep oxygenations at C5 and C21/C7 in a relatively efficient manner, it is unable to convert ophiobolin F to ophiobolin C and produces instead several unexpected derivatives (PubMed:27116000).
What are the official names of this protein?
Ophiobolin F synthase oblA, acOS, Bifunctional sesterterpene synthase oblA, Ophiobolin biosynthesis cluster protein A.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the FPP/GGPP synthase family.
Protein: COFH_METVS
Sequence: MDLISFKEKDISKKECLELFLDTENFFDILKVADDIRKESVGDTVTYVLNANINFTNVCSGTCKFCAFKTEKEDPNSFFLNPDKVAEKALLARKTGATEVCIQGGLLPEIDTYFQAEILQKVKKITEKYGGIDIHAFSPMEVKSAAENCGLNVKEALKILKDSGLKTMPGTAAEILNDEIRNEICPTKLTTSEWIDVVKTAHKNGIKTTCTMMYGHIEENVHLVEHLSILKEIQKETSGFTEFVPLTFLHENAPLHHIGKVKSGASGILDLKVYAISRIFFKNYLKNIQTSWVKLGIKLSQISLNCGANDVGGTLMEESISKAAGGSFGTCMSEEKLKNMILNVNKIPKKRNTLYELIN
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
What are the official names of this protein?
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase, FO synthase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofH family.
Protein: EMC5A_XENLA
Sequence: MASSIWKGLVGIGLFALAHAAFSAAQHRSYMRLTEKEDETLPIDIVLQTLLAFIVACYGIVHIAGEFKHMDATSELRNKTFDTLRNHPSFYVFNHRGRIMFQPPESEDCHRNQAPFSSNSSLKLSKLEAMHR
What is the function of this protein?
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.  Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues.  Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices.  It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes.  By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors (By similarity).  By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes.  May be involved in Mg(2+) transport (By similarity).
What are the official names of this protein?
ER membrane protein complex subunit 5-A, Membrane magnesium transporter 1-A.
What is the protein family that this protein belongs to?
Belongs to the membrane magnesium transporter (TC 1.A.67) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein.
Protein: RS18_DESVH
Sequence: MAFKKKFAPRRKFCRFCADKELPIDYKRADILRDFITERGKIIARRITGTCAHHQRVLTREIKRARQMALLIYTATHSSDVKKKSIL
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: UPP_CAMC1
Sequence: MQNVKLISHPLIEHKLTILRDKNTQPFQFRMLVDEISYLMIFEATRNLKVKDVKVQTPVALADAKRLTTKVMICPILRAALGMLDSVFTIIPDASVGFLGFQRNEETAQAEFFYAKLPKDAKERMAIIIDPMFATGGTAIDAVKFLREKGVKEIKFISIIAAPEGLKRFSEIYPDVEVYTASIDEKLNEKNYIVPGLGDAGDRVFNTL
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: GSHB_GLOVI
Sequence: MKILFIVDPLETLKPGHDTSVALMQAAARRGHSVWAAEVGDLQVHHHRAAAQVRTLTIHPGRTPFYTVEAVGFYPLSEADVIWMRKDPPVTSAYLWATQVLDLVNAGRGDGRTTFVLNRPSGLRNDNEKLYALHFPDLVPETRVCTHRQDILDFVDIHGRAVIKPLDGKGGEGIFLLARADRNLNAIIEASTAYGTRHVMVQRYLEESRQGDKRIVLLAGEPIGALLRVPREDDVRGNMAAGGRVVKTTLTERDREICRVVGPRLVADGHYFVGIDVIGAYLTEINVTSPTGICEIDVLDGVVLEDEIVDWLVEYTRPALARNL
What are the official names of this protein?
Glutathione synthetase, GSH synthetase, GSH-S, GSHase, Glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic GSH synthase family.
Protein: SSPN_GEOKA
Sequence: MSNPKGSRKHFVPNHIGTQPRAAGGNKGKQMQDQSGQHAQVIQTKGE
What are the official names of this protein?
Small, acid-soluble spore protein N, SASP N.
What is the protein family that this protein belongs to?
Belongs to the SspN family.
What are the subcellular locations of this protein?
Spore core.
Protein: SRT55_CAEEL
Sequence: MKLRHFLIFLMLIPISSSICFDLKTLQCWPMEIQEMALMLTARNTARYDCSGKSKSEWYETGQKRLGWGIYYISSGLFFQLIGWPVIWVFITKFSMTNALKVYRIMVFIGLIEITEIWGNSVFPGFVAVFGEVYCTSPILMTIVGKMTMVQWVLGSSSAAFLGFHRLCDMIQKLEWLVNTNTKTGLWLTVLFFYACYGSIFFDTVLFNSDYMAPLLDPMIGKQGIIYSNNFLYFHNIIVATTLILVYACLCTLWSSREMNTSSLHVSKFQRSILLQSICISLTYAIPAISFVTMFVLPIPKWFFHVSDITYQLSGGLPFIMYICLNKRVREEFLHLLRVCRKAEKSQVAVIPLGNSTVSAFNN
What are the official names of this protein?
Serpentine receptor class T-55, Protein srt-55.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein srt family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HCYB_ASTLP
Sequence: DASGATLAKRQQVVNHLLEHIYDHTHFTDLKNIAGTFSPEAATSIYTDDMEELRDGRLLEQHHWFSLFNTRQRMLFEVLIHCKSWECFLDNAAYFRERMNEGEFVYAIYVAVIHSGIGHGIVIPPIYEVTPHIFTNSEVINKAYSAKMTQTPGRFNMDFTGTKKNKEQRVAYFGEDIGMNIHHVTWHMDFPFWWKDSYGYHLDRKGELFFWVHHQLTARFDSERISNWIDVVDEIHWSCIEGFAPHTSYKYGGEFPARPDNVHFEDVDGVARVRDSRIRDALAHGYLLDNSGNKSSVYSPNVQYYGAIHNTAHIMIGRQGDHKFDMPPGVMEHFETATRDPSFFRLHKYMDNIFKEHKDSLPPYTKNDIAVPGVVIDSVAQLKTFFDTFEVNLGNAKVADVAISADVHRINHEEFSYNIDISNTDKIFICPVKDDNGIMDKFYKSIDPGTNHIVRKSVDSSVTVPDRQYALDLHMFERSCGIPNRDMIIIESRPDGMDFALFVTVDDPEEIGATHSQHGIKKYPDKKPMGYPVDRSIPDNRVFLESPNIKRTYVKVFHDEHGGEQH
What is the function of this protein?
Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods.
What are the official names of this protein?
Hemocyanin B chain.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family. Hemocyanin subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: RISB_CITBB
Sequence: MPKYVEGKLNAEGLRFGIVVGRFNSFIGERLLEGALDALLRHGANDAQITVVRVPGAFEIPLTAQKMAGSGNYDALICLGAVIRGSTPHFDYVSSEVSKGIAHVSLATGVPVAFGVLTTDTIEQAIERAGTKAGNKGFDAAMTVIEIANVFKEMK
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: MAKR1_ARATH
Sequence: MRRQPPRPRNSPPQSHSSPSSSSSEFEFNISISPRKASSSLCPADELFYKGQLLPLQLSPRLSLVRTLGSSTSSSDYTSSSSSSVATSAARDSTESNSSTDSTASFPLLHPPPLDCCDSSRPSSVTDDEDFFFKPPKNKSSSGGFSLSRFSSVFKKDPKTNLHHHSSSSSTATTAAAPSSVKRMSSTAKEVIRKYMKKVKPLYEKLSPKQSSNIKTESSSSLKDSGNNIRGTTTVTTVTAAPTVVSSGGGLSISFSGNLMKYTKRGRCAASCPSSMRSSPNHSGVLTRGGFPVHQGSCSSSSSNNNSVSSSMEELQSAIQGAIAHCKNSMLQKNLVSSLEI
What is the function of this protein?
May negatively regulate brassinosteroid signaling.
What are the official names of this protein?
Probable membrane-associated kinase regulator 1.
What are the subcellular locations of this protein?
Cell membrane.
Protein: CCSA_SACHY
Sequence: MLFATLEHILTHISFSTISIVITIHLITLLVRELRGLRDSSEKGMIATFFSITGFLVSRWVSSGHFPLSNLYESLIFLSWTLYILHTIPKIQNSKNDLSTITTPSTILTQGFATSGLLTEMHQSTILVPALQSQWLMMHVSMMLLSYATLLCGSLLSAALLIIRFRNSFDFFSLKKNVLRKTFFFSEIEYLYAKRSALKNTSFPVFPNYYKYQLTERLDSWSYRVISLGFTLLTVGILCGAVWANEAWGSYWNWDPKETWAFITWTIFAIYLHSRTNPNWKGTNSALVASIGFLIIWICYFGINLLGIGLHSYGSFTLPSK
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PSBT_VITVI
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPTKKVK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GPDA_GEOSM
Sequence: MAEKIAVIGAGSWGTTLADLLAKKGHEVTLWAYEPELVLEMRDTRENSLFLPGIKLNEGLAFTNDLAQAYRGCSMVLCVVPSQLVRRVMTNSLPFLPREAVIVSASKGIEVDTLATVSEIYQEILPPEQYRNLAALSGPSFAREVALEMPTAVTAAASTEAVARRVQEAFTTSYFRVYRNSDVVGVELGGAIKNVIAIAAGISDGLGFGSNTRAALITRGLAEMTRLGVAMGAQPSTFAGLAGMGDLVLTCTGDLSRNRSVGIQIGQGRTLSEILGEMRMVAEGVKTTESAYNLAKKLGVEMPIIEQMYQMLYQSKPAREAVLELMTRNLKAEGV
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_BUCCC
Sequence: MKNINPMKTHAWKKLQNHFFDVKNIYIKDFFCLDKNRFANFSVFFKDFMLIDFSKNRISSQTLKLLFQLAQECYLDDAIKNMFLGKIINKTENRPVLHVALRNRLNNKIILNNIDIMNEIQIELKKIKCFSESIIDGSWKGFTGKSISDVVNIGIGGSYLGPYMITEALKIYKNHLNIHYISNIDGTEISEVLKKINLETTIFLIASKSFSTDETISNANYLKKWCILKTNYKKYFSKHFFALCENIKTAINFGIKYENIFKFWDWVGGRYSLWSSSGLSIVLSIGFKNFESLLYGAYLMDQHFLHTKISKNIPIILALISIWYTNFFNTETEAIFPYDKYLHVLPEYLQQSYMESNGKSIDRNGKLVTWNTCPIIWGSTGTNGQHSFFQLLHQGTTMVPCDFIIPAISHNLINDHHKKLLSNFLAQTASLAFGNINKDIMNMNLKYSSENFIFSHKTYFGNKPSNSIFLKKITPISLGSLIALYEHKIFVQGVILNIFSFDQWGVELGKTVANNIYNNLFKKKKINVYDCSTIGLINLYKYWNRI
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CATIN_MOUSE
Sequence: MRGAGRQMGRDSRSRSRSVGRRGRKQRSRSRGRSRSRSRSRSRSRSRSRSRSRSHGRSSRRRREHERRRERKRRSRGRRSDSEGEQRQKSRRRSQSLRPPRWHSQNQSSCSDSGEERAQGSWARKGHRRSWSPGSSASSLDSPRRSRSPGTATLALSQQQSLQERLRLREERKQQEELLKAFETPEEKRARRLAKKEAKERKKREKMGWGEEYMGYTNTDNPFGDNNLLGTFIWNKALEKKGISHLEEKELKERNKRIQEDNRLELQKVKQLRLEREREKAMREQELELLQREKEAEHFKTWEEQEDSFHLRQAKLRSKIRIRDGRAKPIDLLAKYISAEDDDLAVEMHEPYTFLNGLTVADMEDLLEDIQVYMELEQGKNVDFWRDMTTITEDEIAKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGPNLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLFKLKQEQGVESEPLFPILKSEPSAAHSPEPEERPPSPGTSVDPVEPVEPEEATAPGEAEGEAEGEAVLMEEDLIQQSLADYDAGRYSPRLLTAHELPLDAHVLEPHEDLQRLQLSRQQLQATGDASESAEDIFFRRAREGMGQDEAQFSVEMPLGGRAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIRKRATPEYFLEACADNRDFAILRFHAGPPYEDIAFKIVSREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR
What is the function of this protein?
Plays a role in pre-mRNA splicing by facilitating excision of a subset of introns (By similarity).  Required for the splicing of CDCA5/Sororin, a regulator of sister chromatid cohesion (By similarity).  Involved in the regulation of innate immune response (By similarity).  Acts as negative regulator of Toll-like receptor, interferon-regulatory factor (IRF) and canonical NF-kappa-B signaling pathways (By similarity).  Contributes to the regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous pro-inflammatory stimuli (By similarity).
What are the official names of this protein?
Splicing factor Cactin.
What is the protein family that this protein belongs to?
Belongs to the CACTIN family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Note=Nuclear localization with a speckled expression pattern in some cells. Colocalizes with NFKBIL1 in the nucleus (By similarity).
Protein: HISX_CUTAK
Sequence: MLRIVDVTSETTDDLRCAVPRADFDVDAAMAAVIPVCSAVRDRGVEALREYSEKFDHVVPEHLRVPVEALATAAANLDGTLRRAFSESIRRRRQVCQEAEVETSSQPVEVAGGARVSQRIVPVGRVGLYVPGGFAPLASSVIMNVVPAQEAGVSSIAVASPPQAEFGGLPHPSILALCHLLGVNEVYAVGGAQAIAMFAYGVEGSDEADSCPRVDMVTGPGNIYVVAAKRCLRGTVGIDSEAGPTEIAILADETADPRHIAADLMSQAEHDTLAAAVLVTDSTTLAEAVQRELAPMVSATLHSERIRTSLTSKQSAIVMVRDIDQGLEVVNAYAAEHLEIQTADAAAVAARVWNAGAIFVGPWAPVSLGDYSAGSTHVLPTAGAACHSSGLSVRSFMRAVHVIDYTEDALLELADSVEAFALAENLPGHANAITVRRSR
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: ULAB_ECOLI
Sequence: MTVRILAVCGNGQGSSMIMKMKVDQFLTQSNIDHTVNSCAVGEYKSELSGADIIIASTHIAGEITVTGNKYVVGVRNMLSPADFGPKLLEVIKEHFPQDVK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II UlaABC PTS system is involved in ascorbate transport.
What are the official names of this protein?
Ascorbate-specific PTS system EIIB component, Ascorbate-specific phosphotransferase enzyme IIB component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO11_THEKO
Sequence: MRIEVIRREENLLEFYLEGEDHTFANLLTETLHENEHVTFAGYTIEHPITMARKPRFKVVTDGKITPEKALEEAAQKIFDRAREVLEAWKAAIE
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit L.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBP2_MOUSE
Sequence: MSQLSSTLKRYTESSRYTDAPYAKPGYGTYTPSSYGANLAASFLEKEKLGFKPVSPTSFLPRPRTYGPSSILDCDRGRPLLRSDIIGSSKRSESQTRGNERPSGSGLNGGSGFSYGVSSNSLSYLPMNARDQGVTLSQKKSNSQSDLARDFSSLRTSDGYRTSDGYRTSEGFRIDPGNLGRSPMLARTRKELCALQGLYQAASRSEYLTDYLENYGRKGSAPQVLTQAPPPSRVPEVLSPTYRPSGRYTLWEKSKGQASGPSRSSSPGRDTMNSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLGHTSSAHTALMEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFMGYNQQDAQEFLRFLLDGLHNEVNRVAARPKASPETLDHLPDEEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPIAKRGYPEVTLMDCMRLFTKEDILDGDEKPTCCRCRARKRCIKKFSVQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREFASENTNHAVYNLYAVSNHSGTTMGGHYTAYCRSPVTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYELASPPSRM
What is the function of this protein?
Circadian clock output effector that regulates Ca(2+) absorption in the small intestine.  Probably functions by regulating protein levels of the membrane scaffold protein NHERF4 in a rhythmic manner, and is therefore likely to control Ca(2+) membrane permeability mediated by the Ca(2+) channel TRPV6 in the intestine.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 2, 41 kDa ubiquitin-specific protease, Deubiquitinating enzyme 2, Ubiquitin thioesterase 2, Ubiquitin-specific-processing protease 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Note=Localizes in the spermatid head in late-elongating spermatids in the thin area between the outer acrosomal membrane and the plasma membrane. SUBCELLULAR LOCATION: [Isoform 2]: Nucleus. Membrane; Peripheral membrane protein. Cytoplasm. Note=Predominantly expressed at membranes.
Protein: NAGB_VIBVY
Sequence: MRLIPLKTAAQVGKWAAAHIAKRINDFQPTAERPFVLGLPTGGTPLATYKALIELYQEGKVSFKHVVTFNMDEYVGISADHPESYRSFMYNNFFNHIDIQEENINLLNGNAEDHEAECQRYEDKIKSYGRINLFMGGVGNDGHIAFNEPASSLSSRTRIKTLTEDTRIANSRFFDGDINQVPKYALTIGVGTLLDSQEIMILVTGHNKALALEAAVEGSVNHLWTVSALQLHPKSVIVCDEPSTQELKVKTVKYFTELEAKNIVGF
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: RL18_PETMO
Sequence: MIKQLDKKALRQKRHLRVRKNVRGTSEKPRLTVFKSQKHIYAQIIDDTKGVTLASASTTQKQLKEKLEKTWDENAAKEVGKLIAEKAKEKGITEIVFDRSGYKYHGKVKALAEAARETGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: ATX1_ARATH
Sequence: MACFSNETQIEIDVHDLVEAPIRYDSIESIYSIPSSALCCVNAVGSHSLMSKKVKAQKLPMIEQFEIEGSGVSASDDCCRSDDYKLRIQRPEIVRVYYRRRKRPLRECLLDQAVAVKTESVELDEIDCFEEKKRRKIGNCELVKSGMESIGLRRCKENNAFSGNKQNGSSRRKGSSSKNQDKATLASRSAKKWVRLSYDGVDPTSFIGLQCKVFWPLDALWYEGSIVGYSAERKRYTVKYRDGCDEDIVFDREMIKFLVSREEMELLHLKFCTSNVTVDGRDYDEMVVLAATLDECQDFEPGDIVWAKLAGHAMWPAVIVDESIIGERKGLNNKVSGGGSLLVQFFGTHDFARIKVKQAISFIKGLLSPSHLKCKQPRFEEGMQEAKMYLKAHRLPERMSQLQKGADSVDSDMANSTEEGNSGGDLLNDGEVWLRPTEHVDFRHIIGDLLIINLGKVVTDSQFFKDENHIWPEGYTAMRKFTSLTDHSASALYKMEVLRDAETKTHPLFIVTADSGEQFKGPTPSACWNKIYNRIKKVQNSDSPNILGEELNGSGTDMFGLSNPEVIKLVQDLSKSRPSSHVSMCKNSLGRHQNQPTGYRPVRVDWKDLDKCNVCHMDEEYENNLFLQCDKCRMMVHAKCYGELEPCDGALWLCNLCRPGAPDMPPRCCLCPVVGGAMKPTTDGRWAHLACAIWIPETCLSDVKKMEPIDGVNKVSKDRWKLMCTICGVSYGACIQCSNNSCRVAYHPLCARAAGLCVELENDMSVEGEEADQCIRMLSFCKRHRQTSTACLGSEDRIKSATHKTSEYLPPPNPSGCARTEPYNCFGRRGRKEPEALAAASSKRLFVENQPYVIGGYSRLEFSTYKSIHGSKVSQMNTPSNILSMAEKYRYMRETYRKRLAFGKSGIHGFGIFAKLPHRAGDMMIEYTGELVRPSIADKREQLIYNSMVGAGTYMFRIDDERVIDATRTGSIAHLINHSCVPNCYSRVITVNGDEHIIIFAKRHIPKWEELTYDYRFFSIGERLSCSCGFPGCRGVVNDTEAEEQHAKICVPRCDLIDWTAE
What is the function of this protein?
Trimethylates A4/EF1A post-translationally at Lys-396 (PubMed:21245040).  Required for actin cytoskeleton organization (PubMed:21245040).
What are the official names of this protein?
Histone H3-lysine(4) N-trimethyltransferase ATX1, Protein SET DOMAIN GROUP 27, Protein-lysine N-trimethyltransferase ATX1-SoloSET, Trithorax-homolog protein 1, TRX-homolog protein 1.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
What are the subcellular locations of this protein?
[Isoform 1]: Nucleus. Cytoplasm. Note=Shifts from nucleus to cytoplasm as PIP5 levels increase. When in the nucleus, associated with chromatin. When cytoplasmic, mostly localized along the plasma membrane, associated with PIP5. SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm. Cytoplasm, perinuclear region.
Protein: KDSA_PHOLL
Sequence: MQQKVVHIGDIKVANDLPFVLFGGMNVLESRDLAMSICEHYVTVTQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHESAQAQPVAEVVDVIQLPAFLARQTDLVEAMARTGAVINVKKPQFISPGQMGNIVDKFKEGGNDQVILCDRGSNFGYDNLVVDMLGFNVMAQATGGHPVIFDVTHSLQCRDPFGAASGGRRAQVAELARAGMAVGIAGLFLEAHPDPANAMCDGPSALPLAKLEPFLSQMKAIDDVVKSFPQLDTSK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_ALKOO
Sequence: MMENNKRKRKARKKICVFCADKSKNIDYKDVHKLKKYITERGKILPRRISGNCAIHQRELTQAIKRSRHIALLPYTMD
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.