PharMolix/UniProtQA huggingface dataset:
Protein: ACKR3_HUMAN
Sequence: MDLHLFDYSEPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMIANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVTHLIFSINLFGSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDTYYLKTVTSASNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAISASSDQEKHSSRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVTQCLSLVHCCVNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQSTK
What is the function of this protein?
(Microbial infection) Acts as coreceptor with CXCR4 for a restricted number of HIV isolates.
What are the official names of this protein?
Atypical chemokine receptor 3, C-X-C chemokine receptor type 7, CXC-R7, CXCR-7, Chemokine orphan receptor 1, G-protein coupled receptor 159, G-protein coupled receptor RDC1 homolog, RDC-1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Atypical chemokine receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Early endosome. Recycling endosome. Note=Predominantly localizes to endocytic vesicles, and upon stimulation by the ligand is internalized via clathrin-coated pits in a beta-arrestin-dependent manner. Once internalized, the ligand dissociates from the receptor, and is targeted to degradation while the receptor is recycled back to the cell membrane.
Protein: YLF7_SCHPO
Sequence: MLHFLFHSGSSSNRNSSPKESYELLHGLDKQYQSTKDVTFRLVLVQDIGDRKKTVLFDSNHVDGQKGDSVLRDSANAPLTDLMFGAIPISHKGTTTKLHILHPPNPATRSYMLTQLFQINTHGTVVNSSHETIASATSLFENSSSNFSEDPNKPNSSDAFESNKEDSPLLKSFNDSAIPENAANLSSSSKNMKDSTLSSQKARSNTSSSFLTPLHEQLESRCALHTAAKDPFRSKNSLRCNRGHSPLSSQQILPAISNNTSEKPDSNNCGFLLPSNSTSIKDLKNVKKGNRLNSPPFITIPQSIKNTNSNFLLSSPSLFSDTRTRPASYALALIITVPYEYDEIVHPVSTYYTMLSNFTLSLQKEIDERIRNLLFVSLSSGGDNKNDTGIPLIQSSSSKVGFGPYALSKDLITAKSFHKCILLLKTGFSAPLIKPSVFSGSKWVENMRLLTDLCKSPAQKCLFSNLLTATRKFCLERQKDDVTFKVLLQSSKAPIARRFLYLLAPLMRPSIAQCSDTLLNPIQLYPNSGILSSSSLSTSFGCPSVSGSLRVPSYDMKINDSCKAIDIHSEKPSFADSPRKTSLRNYLSSSWRLKFMRSSYQNNETDPLNPTSGSFLRQPMQYSSPSGVSESAASSFLDIENIDEYLESAENMKYLPRSTVGPGGMLHVDLLETNAKQESEATTSTVPPSPSQVGFLKALHPSFDLQAAPPNSYVSFSDDDFISATLLYMLEDVSRNKSQLLAEKKHLKSQLMVANLDTYSLDCYEIHEFPSEWENDYAPFLLKEHHKVIGETYVSSFDIQQGCFNVIKRRLSSYKWDKSDDSFVSEVLKGDLKEVLRVCSHC
What are the official names of this protein?
Uncharacterized protein C30C2.07.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2A1C_MOUSE
Sequence: MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKAKGK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A type 1-C, H2A-clustered histone 6.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SYV_DESPS
Sequence: MAQDSLLSKGYEFADVEEKWLSRWHKQNAFATKMEDGKDAFSIVIPPPNVTGVLHVGHALNNTLQDILVRYHRMCGDNTMWIPGTDHAGIATQNVVERQLATEGKGRHDLGREAFIERVWKWREDKGGTIVNQLKKIGSSCDWERERFTMDEGLSTSVREVFVRLYKEGLIYKGDYIVNWCPRCQTALADDEVEHEDSKGKLYHIRYPFADGSGSVVIATTRPETMPGDTAIAVHPDDERYAHLGEIGIKLPLTDRILPVVFDHHVEKDFGTGALKVTPSHDRNDYEIGIRHGLDLCKVIDEKGMMNDNAGKYAGLDRFECRKQIVEDLREQGYLVEIEDYDHAVGHCYRCKTVIEPTTSLQWFVSVKPLAAKAVDAVRDGQINIYPKTWYNTFYSWMDNIRDWCISRQIWWGHRIPAWSCADCGELIVETEDPTSCPKCGSSKLSQETDVLDTWFSSALWPFSTMGWPENTKELQTFYPTSVLITSFDILFFWVARMMMMGLHLMDEVPFKDVYLHALVRDKHGKKMSKSTGNVIDPLEIMAQYGTDSMRFTLTAFAAQGREIKLDEDRIEGYRHFINKIWNAARFAQMHIGDCDDSIRVAVETPKDLALGHRWILSRTAKLVEGIHRSLRGYLFNEVASLNYQFIWKEFCDWYLEWIKSDLFSDDLVARDQARGCLMVVLETILKTLHPITPFVTEEIWSVLPGERGFLATSAFPEVREEWKDEEAEAEMELLMGIITGIRNIRSEAEVHPSTKINATVICHDSKRADIIRSYTSGISDMTRLEGFTVVAEAEKPADAATYIYNDIEIFVPLAGLVDIEAELEKLSRERKKVEAKLKQINGKLGNAKFLAGAPEAVVAKVTGEKEELDAKLAKIDEASDRLKKLS
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUP4_CAEEL
Sequence: MKIIIFVCFILIFYLPIQKKHVNSQQQGIDSDDGDAESFFNKSYSEHQSALEQKIFRGYNPKNRPMKNASFPTIVDVHWHIIHVSINQREQTMTVHGHIYMRWFDEFLVWDPKDFNNIQYARVKKWQVWQPKIKVSNSASGLGSAFDFSTSAHVIIQMMGKDRAKVEMYPTFSIKVGCAFDFTDYPYDLNKCAINLFSTSTMADVQLQNLYAIPPTLSFGWEEQKMKRIISDFKIQNVSSSALYYTNGNITSSAPITGFDLGSTWSMLAVTVSFVRHSPLFEAAVVTPCIVVASLISMTFFIDSLSSTFLLMMLHFYVQLIFLHDLVEKLPLSVSEIPFCIKLIGILMYTNGLTLVLHSSLLCGSYYKCPVPQQLNKIFVIEEYIPNTFKEKVQIKKEESNKSWRDLMKLIRPIIGFVLIILLICMFFVCLLL
What is the function of this protein?
Thought to regulate endocytosis in coelomocytes through modulation of phospholipase C activity.  Possible acetylcholine receptor.
What are the official names of this protein?
Acetylcholine receptor-like protein cup-4, Coelomocyte uptake defective protein 4.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein: 1002L_ASFP4
Sequence: MGNKESRYLEMCSEEAWLNIPNIFKCIFIRKLFYNKWLKFQEKKLKKSLKLLSFYHPKKDFVGIRDMLQMAPGGSYFITDNITEEFLMLVVKHPEDGSAEFTKLCLKGSCIVIDGYYYDNLHIFISETPDIYKYPLIRYDR
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 100-2L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 100 family.
Protein: KC1G3_MOUSE
Sequence: MDNKKKDKDKSDDRMARPSGRSGHSTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKIQQSKNQVVSSTNGELNTDDPTAGRSNAPITAPTEVEVMDETNCQKVLNMWCCCFFKRRKRKTIQRHK
What is the function of this protein?
Serine/threonine-protein kinase.  Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates.  It can phosphorylate a large number of proteins.  Participates in Wnt signaling (By similarity).  Regulates fast synaptic transmission mediated by glutamate.
What are the official names of this protein?
Casein kinase I isoform gamma-3, CKI-gamma 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_DICT6
Sequence: MLAWVIIVSIITAGLSVALVGMNATKAQGNAAASALESVARQPEAGDQINRMLLFALAFIETIMIFTLTVALILLFANPLLGKL
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: 5HT2A_CAVPO
Sequence: KLCAIWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPVPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVAFFIPLTIMVITYFLTIKSLQKEATLCVSDPGTRAKLSSFSFLPQSSLSSEKLFQRSIHRETGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFVTNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFA
What is the function of this protein?
G-protein coupled receptor for 5-hydroxytryptamine (serotonin).  Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD).  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors.  Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways.  Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores.  Affects neural activity, perception, cognition and mood.  Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances.  Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction.
What are the official names of this protein?
5-hydroxytryptamine receptor 2A, 5-HT-2, 5-HT-2A, Serotonin receptor 2A.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Cell projection, axon. Cytoplasmic vesicle. Membrane, caveola. Presynapse.
Protein: ICK30_TRILK
Sequence: MKTIIVFLSLLVLATKFGDANEGVNQEQMKEVIQNEFREDFLNEMAAMSLLQQLEAIESTLLEKEADRNSRQKRCNGKNVPCGSNHSPCCSGLSCEETFGYGWLYKSPYCVIPSNG
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U16-barytoxin-Tl1c, U16-BATX-Tl1c, Toxin ICK-30.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 06 (ICK-Trit) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL36_SHEPW
Sequence: MKVRASVKKICRNCKIVKRSGVVRVICVEPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: PLSB_EDWI9
Sequence: MSGWRKIYYKLLNLILKLLVKSKVIPTDPVAELRLDTTRPVFYVLPYNSKVDLLTLRDRCLALDLPDPLDDNEIDGVILPRYVFIDDGPRVFRYYAPKQASVKLFLDYLDLHRGNPSLDIQMIPVSVMFGRAPGREDHKGAPQLRLLNGIQKFFAVLWLGRDSFVRFSNTVSLRYMADEHGTDKTIAQKLARVARMHFSRLRLAAVGPRLPDRQALFNKLLGSKAIEKAVEDEARSKKISREKAQQNAVALMEEIAADFTYEAVRLSDRVLSWTWNRLYQGINVHNAERVRQLAQDGHEIVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFMEGGRSRTGRLLEPKTGTLAMTLQAMLRGGKRPITLVPVYIGYEHVMEVATYAKELRGATKEKESLPQMVRGLRKLRNLGQGYVNFGEPISLNVWLNQHVPEWREAIDPIEAQRPHWLPASVNSIAGEVMVNINKAAAANAMNLCATALLASRQRALTREQLLEQLECYLQLLQNVPYAPDATLPQRTPQELLDHALQMNKFEVEKDNIGDLIILPREQAVLMTYYRNNIQHMLVLPALVASMVIHHRQISRDELLRQAAVIYPMLKQELFMHYVPETLPQVLSPIIDELCRQQLISLQDDTLIINPPRIRSLQLLAAGVRETLQRYAITFSLLSANPSISRGALEKESRILAQRLSLLHGINAPEFFDKAVFATLVATLRAEGYINDVGDAVREQTLEIYNLLADLLTPEIRLTIESVSIAALEDTGGADGGTA
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RLA2_PODAS
Sequence: MKHLAAYLLLTLGGKATPSAADVKAVLESVGIEADSDRLDKLISELEGKDVNELIAEGSSKLASVPSGGAGGAAAAGGAAAAGGAAEAAPEEAKEEEKEESDDDMGFGLFD
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: HDA_YERPY
Sequence: MLLNTPAQLSLPLYLPDDETFASFYPGENPSLLAAIQSAVHQPHGSYIYFWSREGGGRSHLLHAACAELSQQGEAVGYVPLDKRAYFIPEVLEGMEQLALVCIDNIECIAGDEQWEMAMFNLYNRIVETGRTRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPLSDDEKLQALQLRAKLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILSL
What is the function of this protein?
Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN).  Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity).
What are the official names of this protein?
DnaA regulatory inactivator Hda.
What is the protein family that this protein belongs to?
Belongs to the DnaA family. HdA subfamily.
Protein: MORC2_ARATH
Sequence: MPPMAKNAAVTDVVHLDSDSDSDNGVVGGRESASTIAGAATMAPRETLECRSFWKAGDYFVIPNVVTPTAPGMLEHARVHPRFLHSNATSHKWAFGAIAELLDNAVDEIQNGATFVKIDKINIVKDNSPALVFQDDGGGMDPAGLRKCMSLGYSSKKSNTTIGQYGNGFKTSTMRLGADAIVFSRSTRGGTSTQSVGILSYTFLRKTGQDDVTVPMIDIDISKERPQPIIYGSPEDWAANLEILLKWSPFSTEDELLQQFEDVGTHGTKVIIYNLWLNDEGIYELSFDDDEEDIRLRDESVNDGKRLHHKILELRSHISYHLRYSLRAYASMLYLKKFKNFKIIIRGIPVEQFNIADGFRFPEIIKYKPHTATTEQASTEIKIGFVKEAPKLAICGFNVYHKNRLIRPFWKVTMGGDSTGHGVVGVLEANFIEPAHDKQDFERSSLFQRLEARLKKIVYSYWYSHCHLLGYHKYQMPADKSKKIAIPDQPPTISTVNPSPLPSDKISQGGPIIREINLSNATSSRTVAFASPHLRNSTGLRSNFQPVQLNPQPTAADTGNNLDGKSAGEIRQENLQLFMRCEEYIKKENETEQTVKSLEKELEEFKSKCAHLALLVDAKKKEMQQA
What is the function of this protein?
Mediator of defense signaling triggered by distinct classes of R proteins.  Required during hypersensitive response (HR) that confers disease resistance to turnip crinkle virus (TCV) (PubMed:19704828).  Contributes to resistance against Pseudomonas syringae and Hyaloperonospora arabidopsidis, at early stages prior to cytosolic calcium ions Ca(2+) accumulation (PubMed:20332379).  Required for pathogen-associated molecular pattern (PAMP)-triggered immunity, basal resistance, non-host resistance and systemic acquired resistance (SAR) (PubMed:23250427).  Involved in RNA-directed DNA methylation (RdDM) as a component of the RdDM machinery and required for gene silencing.  May also be involved in the regulation of chromatin architecture to maintain gene silencing (PubMed:24799676).  Exhibits ATPase activity (By similarity).
What are the official names of this protein?
Protein MICRORCHIDIA 2, AtMORC2, Protein CRT1-homolog 1, CRT1-h1.
What is the protein family that this protein belongs to?
Belongs to the MORC ATPase protein family.
What are the subcellular locations of this protein?
Nucleus. Endosome. Note=Present in nuclear bodies near chromocenters. Localized in endosome-like vesicles displaying rapid cytosolic streaming. Accumulates in the nucleus following pathogen- associated molecular pattern (PAMP) treatment or infection with an avirulent pathogen.
Protein: IF2_HELPJ
Sequence: MSDMVDLKKFVTELGKTQKELKNVIEQAKDIGLELKTNFKMTPEQAGKLYKYIVDGIKEQIQANQPTKNPKQDNKDDLNTAATPKPLAKKASKTPKKEETKAQPKPKKTKEKKKEAPAPIIKKKEIEIVNTFENQTPLVENTPKAVSHSQIEKAKQKLQEIQKSREALNKLTQSNTNTTNNANSASNVSNAKKEISEVKKQEQEIKRHENIKRRTGFRVIKRNDETENETENSVTESKKPTQSAAAIFEDIKKEWQEKDKQETKKTKKPSKPKATPTAKNNKSHKIDFSDVRDFKGNDIYDDETDEILLFDLHEQDNLNKEEEEKEARQNINDRVRVQRKNPWMNEAGIKRQSKKKRVFRNDNSQKVIQSAIAIPEEVRVYEFAQKANLNLADVIKTLFNLGLMVTKNDFLDKDSIEILAEEFHLEISVQNTLEEFEVEEVLEGVKKERPPVVTIMGHVDHGKTSLLDKIRDKRVAHTEAGGITQHIGAYMVEKNNKWVSFIDTPGHEAFSQMRNRGAQVTDIAVIVIAADDGVKQQTIEALEHAKAANVPVIFAMNKMDKPNVNPDKLKAECAELGYNPVDWGGEHEFIPVSAKTGDGIDNLLETILIQADIMELKAIEEGSARAVVLEGSVEKGRGAVATVIVQSGTLSVGDSFFAETAFGKVRTMTDDQGKSIQNLKPSMVALITGLSEVPPAGSVLIGVENDSIARLQAQKRATYLRQKALSKSTKVSFDELSEMVANKELKNIPVIIKADTQGSLEAIKNSLLELNNEEVAIQVIHSGVGGITENDLSLVSSSEHAVILGFNIRPTGNVKNKAKEYNVSIKTYTVIYALIEGMRSLLLGLMSPIIEEEHTGQAEVRETFNIPKVGTIAGCVVSDGEIARGIKARLIRDGVVVHTGEILSLKRFKDDVKEVSKGYECGIMLDNYNEIKVGDVFETYKEIHKKRTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity).
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTB_PECAS
Sequence: MQDNVPASGGGPSRLFILRPVATTLLMIAILLAGIIGYRALPVSALPEVDYPTIQVITLYPGASPDVVTSAITAPLERQFGQMSGLKQMSTQSAGGASVITLQFQLELSLDVAEQDVQAAINAASNLLPNDLPYPPTYSKVNPADPPIMTLAVTSSAMSMTQVQDMVDNRIAQKISQVAGVGLVSLAGGQRPAVRVRLNAPALAAYGLTSETIRTAITAANVNSAKGSLDGPTRSVTLSANDQMKSVDDYRKLIVAWKNGAPVRLQDVATIEQAAENIYLGAWANRQQAIIINVQRQPGANVITTTDSINKMLPALKASLPNSVEVATLTDRTTSIRASVKDVQFELLLAIALVVMVIYLFLRNAVATLIPSIAVPLSLVGTFAAMYFLGFSINNLTLMALTIATGFVVDDAIVVIENIARYIEKGEKPLNAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVSILISAVVSLTLTPMMCARMLSHQSLRKQNRFTRASERFFTRLIDTYGTWLRKVLNHPWLTLSVALGTLLLTILLYIWIPKGFFPIQDNGIIQGTVQAPQTVSFSNMADRQQRVASIIMKDPTVESVSSFIGVDGTNAALNSGRLQINLKPLSERSERIPEIISRLQQQTAQIPGIQLYLQPVQDLTIDTQISRTQYQFTLQAMSLDELSVWVPKLMTELKKLPQLEDVSSDWQDGAAVAYVNVDRDSASRLGITMSQVDSALYNAFGQRLVSTIYTQASQYRVVLEHDTTNNTGLDALNDVRLISSDGGTIPLSSIATIEERQGPLAINHIDQFPSTTISFNVASGYALGEAVDAITQAEQQMNLPADITTRFQGSTLAFQSALSSTVWLIVAAIVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALMMAGKDLDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMKPYDAIYQACLLRFRPILMTTMAALLSALPLMLSTGVGAELRQPLGVCMVGGLIMSQILTLFTTPVIYLLFDRLATRFRRVPRQEEETE
What are the official names of this protein?
Multidrug resistance protein MdtB, Multidrug transporter MdtB.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PNP_CLOBJ
Sequence: MIHTLETTVAGRKMKVDFGKTGMLSNAAIFMSYGDTVVMINANASKAPREGIDFFPLSVDYEERLYSVGKIPGGFIKREGKPSDKSILHARSIDRPLRPLFPKGYRNDVQIVNTVLSVEQDNLPEILAINGSSLALCLSSIPFTTPVAAVSVGLVDGEFIINPTVAQRENTILDLTVCATKERVMMVEAGGQEIDEETMYSAIMFGFQECKNIVAFQEEAVAKFGKTKNEPILYKADEEVEKEVKEFAFDMIKEVMYIMDKDERNAQLDKVKEKISEEFSEKYEDKKADIAEVIYKTQKEVVRNMLLNENRRPDGRSFDEVRPISCEVGILPRTHGTGLFTRGLTQVMTVATLGALGDVQILDGIAEEASKRYMHHYNFPSYSVGEVRPLRGPGRREIGHGALAERALEPLIPSEEEFPYTIRLVSEVLSSNGSTSQASVCGSTLALLDAGVPIKRPAAGIAMGLITSDDLEKEKVITDIQGIEDFFGDMDFKVAGTEKGITSIQFDTKIAGLSDNCVRDALEGAKKARLHILGKIKECIPEPRKELSKYAPRTEIICIDPEKIRDVIGAGGKIINKIIADTNVKIEIKEDGKIFVTSNNEPEGVKKAISIIEGLTKEVVQGEIYLGKVTKTTNFGAFVEILPGKEGLVHISKLDFARVEKVEDVVSVGDEILVKVTDIDNQGRINLSRKDAIAKKEEEKDK
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_ACIBY
Sequence: MTLRLNELAPAEGAKREHRRLGRGIGSGVGKTGGRGIKGQKSRKSGGVRPGFEGGQTAIYRRLPKFGFTSQIALKTAEVRLSELSKVEGDIVSLETLKAANVVRRDQIRARIVLSGEITRAFTVQGVALTKGAKAAIEAAGGKVEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: EQTN_RAT
Sequence: MDFILLIFLSGVFLPNIFSLQPTVEQDPGVTISDDQYYDEEENNTDENSAIFQKLEDNGGDTPANEKTGNYYKDIKQYVFTTPDSKGTKTEVSVTATTDLKFTMKDYKSSKATASGEEDKRSEPSRKSSTPNVPAFWTMLAKAINETAVSMDDKDLFYQAIPASDLNSTNEDQLSELEEIKLKLMLGISLMTLILLIPLLIFCFATLYKLRHLRDKTCESQYSVNPELATLSYFHPSEGSNQTVLTEESSFLPPEESGKVVIIESNTVNEAEVTEERISE
What is the function of this protein?
Acrosomal membrane-anchored protein involved in the process of fertilization and in acrosome biogenesis.
What are the official names of this protein?
Equatorin, Acrosome formation-associated factor.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle, acrosome outer membrane; Single-pass type I membrane protein. Note=In the anterior acrosome region, enriched on the inner acrosomal membrane but minimal on the outer acrosomal membrane; in contrast in the posterior acrosome region enriched on both the inner and outer acrosomal membranes.
Protein: HAP2_TETTH
Sequence: MKFLAFGLIYFHFCILNRCEYITSSTIQKCYNSSNEPNNCSQKAVIVLSLENGQIANTEQVVATLNQLSDSGVNKQLQNSFIFEVTKSPVTALFPLIYLQDFNSQPLEQVIATTLFSCKDGFYDSSPTCKFQYDSKGQKILDSQGYCCYCSLSDILGMGNDLSRGKVCYALNLGAGSATAHCLKFSPLWYSAFKIQQYQLYFEVNINIYTVDSQNQKNLKQTLKLSTSNPTMKSSDNSTISKIIGTFTPTQPPADLSSYYLVKPSFPATDPRVLQGISSWMFVDKTMFTLDGTQCNKIGVSYSGFRQQSSSCSQPVGSCLQNQLENLYQSDLILLSQNKQPKYLLESQGNFNQVQFQGQTILQQGLSGSASTLITIEIDAAQIKFVTNLGIGCISQCSINNFESHSGNGKLVALVQNQGNYSAEFVLGFNCSSNVQPIQGQKLFLTANQLYNFNCSVSVNSDISAINNNCTINLYDAIGNQLDSKNILFNTTSTNHTSNQGNNTGQQQSSQEYKSSQSCSDKCSSFWSFWCYFSAGCIKEAFKSIASIAGVASALALVIFLAKNGYLVPIIRFLCCCCCKSKKKENEKNKDKTDKKSIQESCSYDRSCCSHSISQSYQVENKNKYKRSKIQRSFSSESCQDKSKKIINELSNLEETFEANKLYANIDKNSSIFEYFGFKKSFTFILYERNDILFLPQNSTILDMIGALQPQKGSYLAQKFLEIVNKNALKVVSTSPLYLLIE
What is the function of this protein?
During fertilization, required for the formation of intercellular membrane pores and subsequent exchange of gametic pronuclei between cells.  Probably initiates the formation of intercellular membrane pores by inserting part of its extracellular domain into the cell membrane of the adjoining cell in the mating pair.  Mating requires the presence of HAP2 on at least one of the two cells.  Mating efficiency is high when HAP2 is present on both cells, and is strongly reduced when HAP2 is present on only one of the two cells.
What are the official names of this protein?
Hapless 2, Generative cell specific-1.
What is the protein family that this protein belongs to?
Belongs to the HAP2/GCS1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction. Note=Detected at the mating junction.
Protein: MATK_LYOLU
Sequence: MEEFKRYLELDRSQQHDFIYPLIFQEYIYALARGRVLNGSIFFENAGYDNKSSLLIVKRLITHLITQMYQQNHFLFYTNDFNPNKFLGCNTNLYYQMIFEGFAVVVEIPFYLRLVSFLEGKERVKSHNLRSLHSIFPFLEDKFSHLNSLLDILIPHPVHLEILVQTLRYWVKDPSSLHLLRFFLHEYPNWNSLMTPKKFSFYFSKRNQRFFFFLYNFHVCEYESIFVFLRNQSSHLCSISSEIFLERISFYKKIELEEVFTKNFKAFLWAFKDPFLHYVRYRGKSFLASKDXXLLMNKWKYYLVNFWECYFSIWSQPRRIHINQLSNNCVDFLGYLLSVRLKPSMVRSQMIENSFLIENASKQFDTLVPITLLIRYLSKAKFCNVLGHPMSKPVWAALSDSDIIERFGRIYRNLSHYHSGSLKKISLYRIKYILRLSCARTLARKHKSTVRSFLKRLGMGLLEEFFTEEEQVFYLTFPKASSTSGKLYQGRIWYLDIFCINDPANHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FIMA1_ECOLX
Sequence: MKIKTLAIVVLSALSLSSTAALADTTPTTVNGGTVHFKGEVVNAACAVDAGSVDQTVQLGQVRTATLKQAGATSSAVGFNIQLNDCDTTVATKAAVAFLGTAIDSTHPKVLALQSSAAGSATNVGVQILDRTGNELTLDGATFSAETTLNNGTNTIPFQARYFATGAATPGAANADATFKVQYQ
What is the function of this protein?
Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0. 5-1. 5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs.
What are the official names of this protein?
Type-1 fimbrial protein, A chain, Type-1A pilin.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.