PharMolix/UniProtQA huggingface dataset:
Protein: EIS_MYCBP
Sequence: MTVTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDGAGPGSEVVGMALYMDLRLTVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAECKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF
What is the function of this protein?
Effector that is released into the host cell and affects host immune responses.  Acts as an acetyltransferase that acetylates lysine residues of host proteins.
What are the official names of this protein?
N-acetyltransferase Eis, Enhanced intracellular survival protein, Protein-lysine N-acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase Eis family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasmic vesicle, host phagosome. Extracellular vesicle, bacterial extracellular vesicle. Host extracellular space.
Protein: MURC_NEIMF
Sequence: MMKNRVTNIHFVGIGGVGMSGIAEVLHNLGFKVSGSDQARNAATEHLGSLGIQVYPGHTAEHVNGADVVVTSTAVKKENPEVVAALEQQIPVIPRALMLAELMRFRDGIAIAGTHGKTTTTSLTASILGAAGLDPTFVIGGKLNAAGTNARLGKGEYIVAEADESDASFLHLTPIMSVVTNIDEDHMDTYGHSVEKLHQAFIDFIHRMPFYGKAFLCIDSEHVRAILPKVSKPYATYGLDDTADIYATDIENVGAQMKFTVHVQMKGHEQGSFEVVLNMPGRHNVLNALAAIGVALEVGASVEAIQKGLLGFEGVGRRFQKYGDIKLPNGGTALLVDDYGHHPVEMAATLAAARGAYPEKRLVLAFQPHRYTRTRDLFEDFTKVLNTVDALVLTEVYAAGEEPIAAADSRALARAIRVLGKLEPIYCENVADLPEMLLNVLQDGDIVLNMGAGSINRVPAALLELSKQI
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_PSYCK
Sequence: MKISELRDKSLEELTQLLDEKQLDAFRIRMAKATGQLGNTHEVRVNRRAIAQLQTLINEKQRGDS
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: GLYA1_VIBVU
Sequence: MLKRDMNIADYDAELFAAIQEETLRQEEHIELIASENYTSPRVMEAQGSQLTNKYAEGYPGKRYYGGCEYVDKAEALAIDRACQLFGCEYANVQPHSGSQANSAVYMALLNPGDTVLGMSLAHGGHLTHGSPVNFSGKHYNVIPYGIDEAGQINYDEMETLALEHKPKMIIGGFSAYSQIVDWKRMREIADKVDAYLFVDMAHVAGLIAAGEYPTPVPHAHVVTTTTHKTLAGPRGGLILSNAGEDMYKKLNSAVFPGGQGGPLMHVIAGKAVAFKEAMEPEFKAYQARVVKNAKAMVAQFQERGYKIVSNGTENHLFLVDLIDKDITGKDADAALGAANITVNKNSVPNDPRSPFVTSGIRVGTPAITRRGFTEADAKELANWMCDVLDNIGNEAVIEATKQKVLEICKRLPVYA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase 1, SHMT 1, Serine methylase 1.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_STRM5
Sequence: MSPSPAERAEDLRRQIAQANRAYHELDAPEIPDVDYDRMVRELEALEREHPELARADSPTQQVGARPSGRFAEVRHAVPMLSLSNAFSDEEVADFVRRIDERLGRRSLQFSAEPKMDGLAISLRYEEGHFVLGATRGDGSTGEDVTANLREIGDIPKRLNGKDWPDVLEVRGEVYMARADFEAYNERARLQGGKVLANPRNAAAGSLRQLDPKISAQRKLSFFAYGTGEVQGGELPDTHSGTLAQLGSWGFPVSALCRVVDGTDGLLGYYRDIGERRDGLPFDIDGVVYKLDDRAGQQAMGFVSRAPRWAIAHKFPAQEQSTTVEAIEIQIGRTGAATPVARLAPVAVAGVIVSNATLHNADQIARLDVRVGDSVIVRRAGDVIPEVVSVILDRRPQGTTPWQMPTQCPVCGSEIVREEGAAAWRCSGELSCPAQRKEAIAHFASRRAMDIDGLGDKYIETLVDAGIVKGVADLYRLSRDQLLHLKLVLDAEDPSALAAALKLHLPAEGSGAVLNAVLKLDGNDPGWRAQALVQPASFEWNTKKIATKWADNLIAAIDASRAATLERLLFALGIEHVGESTAKALAQWFGDLELIRHLPWPLFKRVPDIGGEVARSLGHFFEQQGNQQAIDDLLQVGQVRISDAHAPSAKLREGLDLAQLLVESEIPGITRLRAEKLVAALPSAQAVLDAEHGQFVNAGLPDDTARGLAEWLDAEGHGAMLLAAEKAMRQILAKAPALAEIVAGPLDGQTVVLTGTLAQLTRDAAKERLEALGAKVSGSVSKKTSFVVAGTEAGSKLDKAQSLGVPVWDEDRLLAYLAEHE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: AMPA_ECOSM
Sequence: MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XRN2_CAEBR
Sequence: MGVPAFFRWLTKKYPATVVNANEDRQRGVDGRRVPVDCTQPNPNFQEFDNLYLDMNGIIHPCTHPEDRPAPKNEDEMFALIFEYIDRIFSIVRPRRLLYMAIDGVAPRAKMNQQRSRRFRASKEMAEKAASIEEQRRRLIAEGIAVPQKKKDEEEAHFDSNCITPGTPFMARLADALRYYIHDRVTNDPAWANIEIILSDANVPGEGEHKIMDYIRKQRGNPAHDPNTVHCLCGADADLIMLGIATHEANFNIIREEFVPNQPRACELCGQYGHELKECRGAENDTDLGDEYCKPEQREKNFIFLRIPVLREYLEKEMAMPNLPFQFNLERALDDWVFLCFFVGNDFLPHLPSLEIREGAIDRLIKLYKEMVYEMKGYLTKDGIPELDRVEMIMRGLGKVEDEIFKRRQQDEERFKENQKNKKARMQQYGRGRGGRGRGRGQPAYVPSHGILAPMSAPMHHSGESTRQMASDARQAAMQFNATNDANAQAAANLKALLNVKGEQSPAEVAAQESRKRKAEQPIIITDEDEEPKDDIRLYESGWKERYYRAKFDVGSDDVDFRHRVAWAYVEGLCWVLRYYYQGCSSWDWYFPYHYAPFASDFETVGEFKPDFTRPTKPFNPLEQLMSVFPAASKQHLPVEWQKLMTEDESPIIDLYPADFRIDLNGKKYAWQGVALLPFVDEQRLLETLKSVYPTLTDEEKYRNTRGPNRIFIGRNHKSFAFFQQVAESKSNDLVDLDPSLLNGVSGKISYDSTATAPGLPFPSPVSHEECQDLPTNCGICVLYEDPEYPANYVFPAVRLDGAKEAEKTLRPEDWNERRDGRFNPTIGFNRNAPRGGLDLSGQRHINHHVRGAMYDRQGGNDNYRGGYRGGYQGGYDDRRGGRGGGGYRGGYNDSRPDFGRNYAGREGGGPQHYHEHQPGGGHGRPHDQQPYQDNRRGGGYHRGGRGNGPTGYQRPPYRGGRGRGGGGYQGNSSWR
What is the function of this protein?
Possesses 5'->3' exoribonuclease activity.  Plays a role in maintenance of steady-state concentration and turnover of microRNAs (miRNA) by degradation of mature miRNA.  Degradation role is enhanced when in complex with paxt-1.  Partially redundant to xrn-1 in miRNA guide strand degradation.  Implicated in differential regulation of mRNAs such as let-7 by controlling the accumulation of mature miRNA.  Positively regulates molting of the pharyngeal cuticle.
What are the official names of this protein?
5'-3' exoribonuclease 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RIMO_HAEDU
Sequence: MRDVPNIGFISLGCPKNLVDSERILTELRSDGYNIIPSYENADLVIVNTCGFIDSAVQESLEAVGEALKENGKVIVTGCLGAKENQIREVHPKVLEITGPHSYEAVMQHVHKYVPRPERNMYTSLVPAQGVKLTPKHYAYLKISEGCDHRCTFCIIPSMRGDLDSRPIVQILDEAKRLADSGVKELLIVSQDTSAYALDQTKENQNKTVFWNGVPIKNNLISLCEQLATLGIWIRLHYVYPYPHVDNLIPLMAEGKILPYLDIPLQHASPKILKAMKRPGSIDRTLERIKQWREICPELTLRSTFIVGFPGETEEDFQMLLDFLTEAQLDRVGCFKFSPVDGAVATEMAEQVPEEVKEERFHRFMQVQQRISVARLQQKIGKTLAIIIDEIDEYGIIGRSMADAPEIDGVVYVDNISQQAVTVGQIILVTITNADEYDLWGTY
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_CAMJR
Sequence: MKHYEVLFILKPTLTEEEVNAKLEFVKEVLTKNSAEIETVVPMGTRKLAYKIKKYERGTYFVIYFKAPTNLIAELERVLRITEEVIRFLIVKYENKKEIAAWEKLSHGIKQSKKEIKPLDAPEIQ
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: THIC_BURMS
Sequence: MNANPKFLSADARVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTSFGGEKNPPIYVYDTSGPYTDPDAKIDIRAGLPALRQRWIDARGDTETLSGLTSDYGRERAADPATAELRFPGLHRHPRRAKAGKNVTQMHYARQGIITPEMEYIAIRENQRRAEYLESLKASGPNGAKLAAMMGRQHAGQAFGAAAFGANAPAEITPEFVRDEVARGRAIIPANINHPETEPMIIGRNFLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWQDQFNLGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGVSENDALKKGMEVKAVEFVKSGSEIYHRQ
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: RR18_ANEMR
Sequence: MNRSKKNSRKRLPAIRSGEFIDYRNISLLRRFVSEQGRILSRRTNRLTSKQQRVLTAAIKQARILASLPFPNSEN
What are the official names of this protein?
Plastid 30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid.
Protein: ISPDF_RHIME
Sequence: MQGEEQFSCGVVIVAAGRGERAGQSAEGPKQYRTIGDRPVIAHTLDIFATWPGAGPVVVVIHPDDEELFAAARKRMAGALELTVVHGGATRQLSVLAGLEAVAATGVEYVMIHDAVRPFFDHTLLDRCGAALRDGAQALLPAIAVADTLKRTKAAGLVAETVPRTDLYAAQTPQCFRLEPILSAHRRAAASGRSDFTDDASIAEWAGIPVLLVEGAVDNFKLTLRRDLSMADEKLTRMAIPDVRTGNGYDVHQLVDGDGVTLCGVFIPHGRKLSGHSDADVALHALTDALLATCGAGDIGDHFPPSDPQWKGAPSRIFLEHAARIVRERGGTVTNADISLIAEAPKVGPHRQQMRENLAAILGISLDRCSIKATTNEKLGFVGRNEGIAAIATATVVYASRSKPDVDDRY
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: AMYB_NIACI
Sequence: MLHSQKRIWKKIGLCLLSFILGITVFTGSFGSKAEAAVAGDFQVSVMGPLAKVTDWNSFKNQLTTLKNNGVYAITTDVWWGYVESAGDNQFDWSYYKTYADTVKQAGLKWVPIISTHRCGGNVGDDCNIPLPSWLWSKGSADEMQFKDESGYVNNESLSPFWSGVGKQYDELYASFAQNFSAYKDMIPKIYLSGGPSGELRYPSYYPAAGWSYPARGKFQVYTETAKSAFRTAMTTKYGSLDKINAAWGTNLTSMSQISPPTDSDGFYTGGGYNITYGKDFLSWYQSVLENHLGVIGAAAHKNFDPVFGVRIGAKISGIHWQMNNPSMPHSAEHAGGYYDYNRLIQKFKDTDLDLTFTALEMYDSGTAPNYSLPSTLVDTVSSIANSKGVRLNGENALPTGGSGFQKIEEKITRFGYNGFTLLRINNIVNSDGSPTAEMSSFKNYVIKHAKPAGDGGGNPVNSVTIYYKKGFNSPYIHYRPAGGTWTDVPGVKMPDSEISGYAKITLDIGSASQLEAAFNDGNNQWDSNNMRNYFFSPGTSTYIPGTNGTAGSIQAGPPITSSDFQALPAYEMSI
What are the official names of this protein?
Beta-amylase, 1,4-alpha-D-glucan maltohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 14 family.
Protein: GATA_STRT1
Sequence: MSFNNKTIEELHNLLVSKEISATELTQATIDDIKAREEAVNAFVTVAEEAALAQAKAIDEKGIDADNLLSGIPFAVKDNISTDGILTTAASKMLYNYEPIFDATAVANAKAKDMIVIGKTNMDEFAMGGSGETSYYGATKNAWDHSKVPGGSSSGSAAAVASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGTFSQTVKENAQLLNVIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKETILDAAKHFEKLGATVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRAEDAKNLDDIYVNTRSQGFGDEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFADYDLILGPTAPSVAFDLDTLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFAQGLPVGLQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: NS1_I78A8
Sequence: MDSNTVSSFQVDCFLWHVRKQVVDQELGDAPFLDRLRRDQRSLRGRGSTLGLDIEAATHVGKQIVEKILKEESDEALKMSMASTPASRYITDMTIEELSRDWFMLMPKQKVEGPLCIRMDQAIMEKNIMLKANFSVIFDRLETLILLRAFTEEGAIVGEISPLLSFPGHTIEDVKNAIGVLIGGLEWNDNTVRVSKTLQRFAWGSSNENGGPPLTPKQKRKMARTARSKVRRDKMAD
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: CAPSD_HBVA7
Sequence: MDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTASALYREALESPEHCSPHHTALRQAILCWVELMTLATWVGNNLQDPASRDLVVNYVNTNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRDRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
What is the function of this protein?
Self assembles to form an icosahedral capsid.  Most capsids appear to be large particles with an icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3 particles consisting of 180 capsid proteins.  Entering capsids are transported along microtubules to the nucleus.  Phosphorylation of the capsid is thought to induce exposure of nuclear localization signal in the C-terminal portion of the capsid protein that allows binding to the nuclear pore complex via the importin (karyopherin-) alpha and beta.  Capsids are imported in intact form through the nuclear pore into the nuclear basket, where it probably binds NUP153.  Only capsids that contain the mature viral genome can release the viral DNA and capsid protein into the nucleoplasm.  Immature capsids get stuck in the basket.  Capsids encapsulate the pre-genomic RNA and the P protein.  Pre-genomic RNA is reverse-transcribed into DNA while the capsid is still in the cytoplasm.  The capsid can then either be directed to the nucleus, providing more genomes for transcription, or bud through the endoplasmic reticulum to provide new virions.
What are the official names of this protein?
Capsid protein, Core antigen, Core protein, HBcAg, p21.5.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus core antigen family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: GRPE_PORGI
Sequence: MNKQKNNRERTPQPEQDTERDEQLTNSHENDIDSAPAAEENDKVADPVEQLTAQLAALNDTHLRLMAEYDNYRKRTLKEKSELIRNGGEKVLVDLLPVIDDFERALSNLGDMSEPAAIKEGVELIYSKFMDYLQKQGVKKIETADLPFDADLCDAVAMIPAPSAEQKGKVIDCVKTGYTLNDKVIRHAHVVVGE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNFB_ECOHS
Sequence: MKITLSKRIGLLAILLPCALALSTTVHAETNKLVIESGDSAQSRQHAAMEKEQWNDTRNLRQKVNKRTEKEWDKADAAFDNRDKCEQSANINAYWEPNTLRCLDRRTGRVITP
What are the official names of this protein?
UPF0482 protein YnfB.
What is the protein family that this protein belongs to?
Belongs to the UPF0482 family.
Protein: LOLA_FRAP2
Sequence: MKKIVLLVTLVFSINYSFANASDDLINKIKNIHSMSASFDQKLINGGRASDNISSKGYMSLKKPKFFRWITTTPNNQEIISNGSKLWIYDGDLEQVIIKKVSNNIAQFPYLILLSKNTDNINKLFTVKELDKNTYLLKPKNDQMIDSIQIKFSDNENLEYLAISTSLNQFTKISFSDVKTDIDIDNNKFDFKIPDDTDVIDETKD
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MIAA_CARHZ
Sequence: MSEKLIIIVGPTAVGKSALGIKVAKKINGEIISGDSMQVYKYMDIGTAKVLPEEREGVPHHLIDILEPFQKYSVALFQKEARRLIKEINERGKIPIIVGGTGLYIRSVIDPYDFTDFSFDPVFRGKLEQAAKEKGSSYLHQMLEKIDPVAAQKIHSNDLRRIIRALEVYEHTGKPISYYWERGKQSKPQYRLLYYGLTMDRALLYQRINERVDKMIEKGLIAEVKRLLQMGFKESTAMQALGYKEIVQYLEGKITLDEAIYLIKRDTRRFAKRQLTWFRRDPRIKWFDSGKESLEKITEKIITEAGVNNFL
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: HGFL_MOUSE
Sequence: MGWLPLLLLLVQCSRALGQRSPLNDFQLFRGTELRNLLHTAVPGPWQEDVADAEECARRCGPLLDCRAFHYNMSSHGCQLLPWTQHSLHTQLYHSSLCHLFQKKDYVRTCIMDNGVSYRGTVARTAGGLPCQAWSRRFPNDHKYTPTPKNGLEENFCRNPDGDPRGPWCYTTNRSVRFQSCGIKTCREAVCVLCNGEDYRGEVDVTESGRECQRWDLQHPHSHPFQPEKFLDKDLKDNYCRNPDGSERPWCYTTDPNVEREFCDLPSCGPNLPPTVKGSKSQRRNKGKALNCFRGKGEDYRGTTNTTSAGVPCQRWDAQSPHQHRFVPEKYACKDLRENFCRNPDGSEAPWCFTSRPGLRMAFCHQIPRCTEELVPEGCYHGSGEQYRGSVSKTRKGVQCQHWSSETPHKPQFTPTSAPQAGLEANFCRNPDGDSHGPWCYTLDPDILFDYCALQRCDDDQPPSILDPPDQVVFEKCGKRVDKSNKLRVVGGHPGNSPWTVSLRNRQGQHFCGGSLVKEQWVLTARQCIWSCHEPLTGYEVWLGTINQNPQPGEANLQRVPVAKAVCGPAGSQLVLLKLERPVILNHHVALICLPPEQYVVPPGTKCEIAGWGESIGTSNNTVLHVASMNVISNQECNTKYRGHIQESEICTQGLVVPVGACEGDYGGPLACYTHDCWVLQGLIIPNRVCARPRWPAIFTRVSVFVDWINKVMQLE
What are the official names of this protein?
Hepatocyte growth factor-like protein, Macrophage stimulatory protein, MSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Plasminogen subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YBIX_ESCF3
Sequence: MMYHIPGVLSPKDVARFREQLEQAEWVDGRVTTGAQGAQVKNNQQVDTRSALYAALQNEVLNAVNQHALFFAAALPRTLSTPLFNRYQNNETYGFHVDGAVRSHPQNGWMRTDLSATLFLSDPQSYDGGELVVNDTFGQHRVKLPAGDLVLYPSSSLHCVTPVTRGVRVASFMWIQSMIRDDKKRAMLFELDTNIQSLKSRHGESEEILSLLNLYHNLLREWSEI
What are the official names of this protein?
PKHD-type hydroxylase YbiX.
Protein: GR59F_DROME
Sequence: MRSSATKGAKLKNSPRERLSSFNPQYAERYKELYRTLFWLLLISVLANTAPITILPGCPNRFYRLVHLSWMILWYGLFVLGSYWEFVLVTTQRVSLDRYLNAIESAIYVVHIFSIMLLTWQCRNWAPKLMTNIVTSDLNRAYTIDCNRTKRFIRLQLFLVGIFACLAIFFNIWTHKFVVYRSILSINSYVMPNIISSISFAQYYLLLQGIAWRQRRLTEGLERELTHLHSPRISEVQKIRMHHANLIDFTKAVNRTFQYSILLLFVGCFLNFNLVLFLVYQGIENPSMADFTKWVCMLLWLAMHVGKVCSILHFNQSIQNEHSTCLTLLSRVSYARKDIQDTITHFIIQMRTNVRQHVVCGVINLDLKFLTTLLVASADFFIFLLQYDVTYEALSKSVQGNVTRYK
What is the function of this protein?
Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
What are the official names of this protein?
Putative gustatory receptor 59f.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr10a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GRPE_HAES1
Sequence: MSEQEKVEQEEISAELETQNEQEKPMEETEIQDGDALENAIARVQELEEQLIQAVKKEQDILLRTRAEIDNIRRRAEQDVEKAHKFALEKFAKDLLETIDNLERALSTPANVENETIKSLVDGVELTLKGLLSTVARFGVEPVGVIGETFNPELHQAISMQPTEGFESNQITVVLQKGYLLNGRVIRPAMVMVAQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METAA_AZOPC
Sequence: MPLNLPRHLPAIEILKRESIFVMDDLRASAQDIRPLKIVLLNLMPVKIATETDFVRLLSDSPLQVNVVFVKMKEHQSKNTSLEHLMAFYKNFEDICEENYDGMIITGAPLELMNFEEVTYWEELQKIFDWASKHVTSTLYICWAAQAGLYHFYGIPKYSLAKKMFGVFQHTTNGSNVPLFRGFDSEFYVPHSRYTEIRKEDILKVPRLKLLVESKESGVHIVSARCGREIFMTGHAEYAPNTLHNEYQRDLDKGIQTEIPKNYYKDNDSTKDVLVSWVAHANLLFKNWLNYYVYQATPYDPKEIEFLEDLNVKE
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.