PharMolix/UniProtQA huggingface dataset:
Protein: ELAV3_XENTR
Sequence: MVTQIISTMETQASNGPGSVGILNGTNGAADDSKTNLIVNYLPQNMTQEEFKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYVDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSSLPKTMNQKEMEQLFSQYGRIITSRILVDQVTGSVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGASEPITVKFANNPSQKTGQALLTHLYQTTARRYTGPLHHQTQRFRFSPITIDSVTNLAGVSLTGPTTAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTSKQHKA
What is the function of this protein?
RNA-binding protein that binds to AU-rich sequences (AREs) of target mRNAs.  May also bind poly-A tracts via RRM 3.  May be involved in neuronal differentiation and maintenance (By similarity).
What are the official names of this protein?
ELAV-like protein 3, Protein ElrC.
What is the protein family that this protein belongs to?
Belongs to the RRM elav family.
Protein: MRR_ECOLI
Sequence: MTVPTYDKFIEPVLRYLATKPEGAAARDVHEAAADALGLDDSQRAKVITSGQLVYKNRAGWAHDRLKRAGLSQSLSRGKWCLTPAGFDWVASHPQPMTEQETNHLAFAFVNVKLKSRPDAVDLDPKADSPDHEELAKSSPDDRLDQALKELRDAVADEVLENLLQVSPSRFEVIVLDVLHRLGYGGHRDDLQRVGGTGDGGIDGVISLDKLGLEKVYVQAKRWQNTVGRPELQAFYGALAGQKAKRGVFITTSGFTSQARDFAQSVEGMVLVDGERLVHLMIENEVGVSSRLLKVPKLDMDYFE
What is the function of this protein?
Involved in the acceptance of foreign DNA which is modified.  Restricts both adenine- and cytosine-methylated DNA.
What are the official names of this protein?
Type IV methyl-directed restriction enzyme EcoKMrr, EcoKMrr, Mrr restriction system protein.
Protein: RPOA_ROSS1
Sequence: MLDIAMPKIEVVTAAENYGRFKIEPLDPGYGHTLGNALRRVLLSSIPGAAITKIKIEGVFHEFSTIPGVKEDVTEIVLNIKGIRLRSYAERPVKISLSKRGAGVVRAADIDAPSNVEIVNPNHYICTIDRDDAAIDMEMTVERGRGYLPADQRDALPIGEIPIDAIFTPVPKVNYVVEHIRVGQATDIDSLLIEIWTDGTIKPGDALSHAAQVLVQYSQTIADFNRLSTEAEPTTAPNGLAIPADIYDTPIEELDLSTRTYNCLKRADITKVGQVLEMDEKALLSVRNLGQKSMEEIRDKLIERGYIPRIGQTSHAARAEIEG
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: GATA_NOSS1
Sequence: MASIRELHEQLVKKERSAVEITQETLDHIQELEPKLHSFLHITAQQALEQARAVDAKIAAGEEIGLLAGIPIGVKDNMCTKGIPTTCASRILENFVPPYESTVTQKLLDAGAVVVGKTNLDEFAMGSSTENSAYQVTANPWDLSRVPGGSSGGSAAAVAAEECVVALGSDTGGSIRQPASFCGVVGLKPTYGLVSRYGLVAYASSLDQIGPFGKSVEDTAILLKAIAGYDHQDSTSLKVEIPDYVASLKPDLKARSKLRIGIIKETFGEGLDSVVEQAVTKAIEQLQRLGAEVHVISCPNFRYGVPSYYIIAPSEASANLARYDGVKYGWRAPEGDNLLSMYKRTRATGFGAEVKRRIMIGTYALSAGYYDAYYLKAQKVRTLIKQDFENAFKNVDVLVSPTAPTTAFKAGEKTADPISMYLNDLMTIPVNLAGLPGLSVPCGFDEQGLPIGLQLIGKVLREDQLLQIAYAYEQSTSWHLSQPKIS
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: PLYA_DICD3
Sequence: MNKVSGRSFTRTSTCLLATLIAGVMTSGVSAAELVNSKALESAPAAGWASQNGSTTGGAAATSDNIYVVTNISEFTSALSAGAVAKIIQITGTVDISGGTPYKDFADQKARSQINIPANTTVIGIGTDAKFINGSLIIDGTDGTNNVIIRNVYIQTPIDVEPHYEKGDGWNAEWDGMNITNGAHHVWVDHVTISDGSFTDDMYTTKDGETYVQHDGALDIKRGSDYVTISNSLFDQHDKTMLIGHSDTNSAQDKGKLHVTLFNNVFNRVTERAPRVRYGSIHSFNNVFNGDVKDPVYRYLYSFGIGTSGSVLSEGNSFTIANLSASKACKVVKKFNGSIFSDNGSVLNGSAADLSGCGFSAYTSAIPYVYAVQPMTTELAQSITDHAGSGKL
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.
What are the official names of this protein?
Pectate lyase A.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family. PLADES subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TILS_CHAGL
Sequence: MNHFNLKLIKRIQNDLIKYNLLKPKKSILIAISGGQDSIVLLKILSILQIQWKWKLSIIYCDHQWNIYSKNQAFHLYKVSFQMGIPFYHGVTIKPLRTEKSARIWRYSVFQRIASISKFNVIVTAHSSTDRVETFLYNLFRGTGVQGLQSLTWKKNIQFEILPNFARSKKSFDLKILSLESKNGIQTYSDYNKLQLIRPLLNITRTELGKFCSNENLPLWPDLTNYNLSIIRNRIRYQTMPYLKIYFNCNLEKILAQIAEILYSENLYFENLSKKIMLKISFEEINSKKLSLSLFKILPLALQRRIIKFFFENHFSKILDFRDIEEIRYYILNLSNNSKFL
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, chloroplastic, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UREE_YERE8
Sequence: MILIEHILGNVKKDPVWQEKLKDATFDLLVLDQREAQKSRCRKLSTQGLDLGISLDRHVVLADGDVLAWDEKTNVAVVVQINLRDVMVIDLSELKSRSPDELIKTCFELGHALGNQHWKAVTKNNEVYVPLTVATTMMDSVMRTHGFQHLPFRFVKGAEILPLLSNSEARLLFGGAEDTDTHVHVASPLDEPHGSGLHVHAIHSHGTGHTHSHDHDHSHSHGDHDHDHKH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_COPC7
Sequence: MTRSFFVGGNWKLNPTSLSAAKALVEALNKADLDPSTEVVVAPPALYLLPIQEIAGKAVKVAAQNAYFKESGAFTGEISPKQISDAGIPYVILGHSERRTLFHETSEVVALKTRAALDNGLKVILCIGETLKEREEGRTAAVCEEQLSAVVKQLKEEDWSNIVIAYEPVWAIGTGKVATTSQAQETHVDVRKYLATAVSPKVASETRVIYGGSVNAANSKDLASQQDIDGFLVGGASLKPEFVDIINARKA
What are the official names of this protein?
Triosephosphate isomerase, TIM, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
Protein: AROA_CALBD
Sequence: MNVKIDGRRKINSNVIVPPDKSISHRSIMIGSLANGVTEIENFLFSDDCLATINCFKNLSTDIEIRNDKIIVKGNGFALSAPKQILDCQNSGTTTRLLLGILSTQEFESILTGDSSLKKRPMKRVTVPLSQMGAEFEFLEKEDFLPIKVKGSKKLKPIEYTLPIPSAQVKSALIFASLKAEGKSVIKESPKSRDHTELMLKHAGANIKSWEKDGVYTVEILPSQISSIKIKIPSDISSAAFFIVLALICEGSSVVIENCILNPTRTGIIDVLKQMGAEIKIEDVENRNGELVGKIVARSSNLRGVKVEKNDIPRIIDEIPILAVAAAFAEGKTIIDHASELRVKESDRIKTTVEMLKSFGAECYELENGLEIIGSREKLKSAVVNSYKDHRIAMAASIMACAVEGESTILDADCVSISFPNFYDILFSSTKKI
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSPD3_BOVIN
Sequence: MRRGAPQDQELVGPGAPGRGSRGAPPPSGPVVPVLVFPPDLVFRADQRSGPRQLLTLYNPTGAVLRFRVLCTAPAKYTVFDAEGYVKPQSCIDIVIRHVAPHPRNYDVQDRFRIELSEEGTEGRVVGRKDITSVLRAPAYPLELQGQSDPTPHPEPHSWTASSTAQPFPENPHPQLATSSFLLFLLMGTVSVAFLLLPLQDELGSQLPQILHVSLGQKLVAAYVLGLLTMVFLRT
What are the official names of this protein?
Motile sperm domain-containing protein 3.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DGR2_YEAST
Sequence: MFKSKTSTLSYDETPNSNEGDRNATPVNPKEKSQTKHLNIPGDRSRHSSIADSKRSSSRYDGGYSADIIPAQLRFIDNIDYGTRLRKTLHRNSVVSNGYNKLSENDRWYFDLFDRKYFENYLEEPTYIKIFKKKEGLEQFDRMFLAQELKIPDVYKSTTYQGEPAVANSELFKNSICCCTFSHDGKYMVIGCKDGSLHLWKVINSPVKRSEMGRSEKSVSASRANSLKIQRHLASISSHNGSISSNDLKPSDQFEGPSKQLHLYAPVFYSDVFRVFMEHALDILDANWSKNGFLITASMDKTAKLWHPERKYSLKTFVHPDFVTSAIFFPNDDRFIITGCLDHRCRLWSILDNEVSYAFDCKDLITSLTLSPPGGEYTIIGTFNGYIYVLLTHGLKFVSSFHVSDKSTQGTTKNSFHPSSEYGKVQHGPRITGLQCFFSKVDKNLRLIVTTNDSKIQIFDLNEKKPLELFKGFQSGSSRHRGQFLMMKNEPVVFTGSDDHWFYTWKMQSFNLSAEMNCTAPHRKKRLSGSMSLKGLLRIVSNKSTNDECLTETSNQSSSHTFTNSSKNVLQTQTVGSQAIKNNHYISFHAHNSPVTCASIAPDVAIKNLSLSNDLIFELTSQYFKEMGQNYSESKETCDNKPNHPVTETGGFSSNLSNVVNNVGTILITTDSQGLIRVFRTDILPEIRKKIIEKFHEYNLFHLEAAGKINNHNNDSILENRMDERSSTEDNEFSTTPPSNTHNSRPSHDFCELHPNNSPVISGMPSRASAIFKNSIFNKSNGSFISLKSRSESTSSTVFGPHDIPRVSTTYPKLKCDVCNGSNFECASKNPIAGGDSGFTCADCGTILNNFR
What are the official names of this protein?
2-deoxy-glucose resistant protein 2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DGR2 family.
Protein: PANC_METPP
Sequence: MRVVHTINELRQALAATRPAALVPTMGSLHEGHLALVKQARDHGGPVVASIFVNRLQFAPHEDFDRYPRTLERDCDLLKGVGCNLVFAPTESELYPEPQTYKVQPPGELADVLEGAFRPGFFTGVCTVVMKLFQCVQPRVAVFGKKDYQQLMVLRGMVRQFALPIEIVAVDTARADDGLALSSRNAYLSEPERAEAPQLAATLHTVQAAVLAAVKSGARIDAAALEAQAMGTLRSRGWAPDYVALRRSSDLQAPADPTAEPLVVLAAARLGKTRLIDNLEI
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AZOR_BORA1
Sequence: MKTLVLLSSILGDRSKSKALADHFLARMCEHEPASDITVRDLAAQPVPYFDAETAGALFTPADARSDAQRAIVALSDALIAELQAAERVVFAVPTYNFNLPAQLKSYLDYVARAGITFRYTPEGVPEGLLQGKQVYVLIARGGKALGTPQDSMTPYLKQMLGFLGMQDVTVIAAEGMAMGEFAAAEGLAQAKARIDELLPQLA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: Y64_SIRV1
Sequence: MITYYYDEKNKELHIKIYILIDQVPNKPTEEELKKVLPKILKDYANMIENGKMKLIDSKEWGIW
What are the official names of this protein?
Uncharacterized protein 64.
Protein: RL21_LEPBP
Sequence: MFAIIELGAKQFKVSPDQVFVAEKTGNTVGSTVETKVLLLSDNNKVNIGSPALSGAKVTLKVLEDCKGEKIHGFKYKKRKNYKKSWGHRQQLQKLQVVSISG
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: CO1A1_CYNPY
Sequence: MFSFVDNRLLVLLAACVLLVRALDQEDIESGLCHQEGTTYSDKDVWKPEPCVICVCDNGNIMCDDVTCGDYPVDCPNAEIPFGECCPVCPDGDGTSYSEQTGVEGPKGEVGPKGDRGLPGPPGRDGNPGLPGPPGPPGPPGLGGNFAPQMSYGYDEKSAGISVPGPMGPMGPRGPPGPSGSPGPQGFQGPSGEPGEPGAAGALGPRGLPGPPGKNGDDGESGKPGRPGERGPSGPQGARGLPGTAGLPGMKGHRGFNGLDGAKGDNGPAGPKGEPGNPGENGAPGQAGPRGLPGERGRPGAPGPAGARGNDGSPGAAGPPGPTGPTGPPGFPGAVGAKGDAGPQGSRGSEGPQGARGEPGAPGPAGAAGPSGNPGTDGQPGGKGATGSPGIAGAPGFPGARGAPGPQGPAGAPGPKGNNGEPGAQGNKGEPGAKGEPGPAGVQGPPGPSGEEGKRGSRGEPGPAGPPGPAGERGGPGSRGFPGSDGASGPKGAPGERGSVGPAGPKGSTGESGRPGEPGLPGAKGLTGSPGSPGPDGKTGPAGAAGQDGHPGPPGPSGARGQSGVMGFPGPKGAAGEPGKSGERGVAGPPGATGAPGKDGEAGAQGPPGPSGPSGERGEQGPAGSPGFQGLPGSPGPAGEAGKPGEQGAPGDAGGPGPSGPRGERGFPGERGGQGPAGAQGPRGSPGSPGNDGAKGEAGAAGAPGGRGPPGLQGMPGERGSAGMPGAKGDRGDAGTKGADGAPGKDGARGLTGPIGPPGPSGAPGDKGEGGPSGPAGPTGARGSPGERGEPGAPGPAGICGPPGADGQPGAKGESGDAGPKGDAGAPGPAGPTGAPGPAGNVGAPGPKGTRGAAGPPGATGFPGAAGRLGPPGPSGNAGPPGPPGPGGKEGAKGSRGETGPAGRSGEPGPAGPPGPSGEKGSPGSDGPAGAPGIPGPQGIAGQRGVVGLPGQRGERGFSGLPGPAGEPGKQGPSGPNGERGPPGPSGPPGLGGPPGEPGREGSPGSEGAPGRDGSPGPKGDRGENGPSGPPGAPGAPGAPGPVGPAGKNGDRGETGPAGPAGPAGPSGVRGAPGPAGARGDKGEAGEQGERGMKGHRGFNGMQGPPGPPGSSGEQGAPGPSGPAGPRGPPGSSGSTGKDGVNGLPGPIGPPGPRGRNGDVGPAGPPGPPGPPGPPGPPSGGFDFSFMPQPPEPKSHGDGRYFRADDANVVRDRDLEVDTTLKSLSAQIENIRSPEGTRKNPARTCRDLKMCHSDWKSGDYWIDPNQGCNLDAIKVHCNMETGETCVYPSQASISQKNWYTSKNPREKKHVWFGETMSDGFQFEYGGEGSDPADVNIQLTFLRLMATEASQNITYHCKNSVAYMDQETGNLKKAVLLQGSNEIEIRAEGNSRFTYGVTEDGCTQHTGEWGKTVIEYKTTKTSRLPIIDIAPMDVGTPDQEFGIDIGPVCFL
What is the function of this protein?
Type I collagen is a member of group I collagen (fibrillar forming collagen).
What are the official names of this protein?
Collagen alpha-1(I) chain, Alpha-1 type I collagen.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: URK_STRP7
Sequence: MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYKDQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQEPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQYLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AVIL_HUMAN
Sequence: MPLTSAFRAVDNDPGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVASLLSQDIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKHVETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAKIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDEIIDQKQKSTIMLYHISDSAGQLAVTEVATRPLVQDLLNHDDCYILDQSGTKIYVWKGKGATKAEKQAAMSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTMGLGKTFSIGKIAKVFQDKFDVTLLHTKPEVAAQERMVDDGNGKVEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVNGKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGTEPRHFMAIFKGKLVIFEGGTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEHYLWYGKGSSGDERAMAKELASLLCDGSENTVAEGQEPAEFWDLLGGKTPYANDKRLQQEILDVQSRLFECSNKTGQFVVTEITDFTQDDLNPTDVMLLDTWDQVFLWIGAEANATEKESALATAQQYLHTHPSGRDPDTPILIIKQGFEPPIFTGWFLAWDPNIWSAGKTYEQLKEELGDAAAIMRITADMKNATLSLNSNDSEPKYYPIAVLLKNQNQELPEDVNPAKKENYLSEQDFVSVFGITRGQFAALPGWKQLQMKKEKGLF
What is the function of this protein?
Ca(2+)-regulated actin-binding protein which plays an important role in actin bundling (PubMed:29058690).  May have a unique function in the morphogenesis of neuronal cells which form ganglia.  Required for SREC1-mediated regulation of neurite-like outgrowth.  Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates.  Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast.  Plays a role in ciliogenesis.  In podocytes, controls lamellipodia formation through the regulation of EGF-induced diacylglycerol generation by PLCE1 and ARP2/3 complex assembly (PubMed:29058690).
What are the official names of this protein?
Advillin, p92.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cell junction, focal adhesion. Cell projection, neuron projection. Cell projection, axon. Note=In podocytes, present in the F- actin-enriched cell periphery that generates lamellipodia and focal adhesions.
Protein: TRMD_SALEP
Sequence: MFIGIVSLFPEMFRAITDYGVTGRAVKKGLLNIQSWSPRDFAHDRHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSELATNQKLILVCGRYEGVDERVIQTEIDEEWSIGDYVLSGGELPAMTLIDSVARFIPGVLGHEASAIEDSFADGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWLRRPELLENLALTEEQARLLAEFKTEHAQQQHKHDGMA
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGDA_LISM4
Sequence: MKIRWIRLSLVAILIIAVVFIGVIGFQKYQFSKSRNKVIMQMDRLMKDQDGGNFRRLDKKENGVEIISYIPKTTEKKDNEIIQKEIGKATDAEVKKLNRDKETQGIIFYTYQKHRMAEQAISYKAVQSEYVKEGRTKFVLKDKKDICKNIVTDAETGALLTLGEVLIKSNQTKLNLKTAVEEELIKTGDFSLKDVGNLGKIKSLVKWNQTDFEITNSEIILPVKIPGAPEPKKVKVKLADIASSVNKRYLPSSVKVPEVPKAKTNKRIALTFDDGPSSSVTPGVLDTLKRHNVKATFFVLGSSVIQNPGLVKRELEEGHQVGSHSWDHPQLTKQSTQEVYNQILKTQKAVFDQTGYFPTTMRPPYGAVNKQVAEEIGLPIIQWSVDTEDWKYRNAGIVTKKVLAGATDGAIVLMHDIHKTTAASLDTTLTKLKSQGYEFVTIDELYGEKLQIGKQYFDKTDSRMVK
What is the function of this protein?
Catalyzes the deacetylation of N-acetylglucosamine (GlcNAc) residues in peptidoglycan (PG).  Deacetylates also N-acetylated PG.  Does not deacetylate N-acetylmuramic acid (By similarity).  Confers host lysozyme resistance.  Critical for virulence and escape from innate immune response of the host (PubMed:21768286, PubMed:25157076).  Required for intracellular survival of bacteria in macrophages of the host.  Required for successful host colonization.  Controls the production of inflammatory mediators in the bone marrow derived macrophages (BMMs) of the infected mouse (PubMed:21768286).  Suppresses Toll-like receptor 2 (TLR2)-dependent secretion of interleukin 6 (IL-6) and interferon-beta (IFN-beta) in the macrophages of the infected mouse.  May decrease accessibility of pattern recognition receptors (PRRs) such as nucleotide-binding oligomerization domain protein (NOD) 1 of the host to the bacterial cell wall components (By similarity).  Protects cells from autolysis induced by lysozyme or by other autolysis-inducing agents (By similarity).
What are the official names of this protein?
Peptidoglycan-N-acetylglucosamine deacetylase PgdA, Peptidoglycan GlcNAc deacetylase, N-acetylglucosamine deacetylase Pgd, Peptidoglycan N-deacetylase, PG N-deacetylase, Petptidoglycan deacetylase, PG deacetylase.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein; Extracellular side. Secreted, cell wall.
Protein: ITP_EHV1B
Sequence: MAREHGSMRALVNSLAGLLGETDTEVPSLEPAMLMVLKSSISEFFLSTDTVSVDEAAELFPRLQFLACRAYAASHTPDAAMLAENLAGLVLWRIHQNWTDREMEAVDQMFVLLEIMNGESGVYMLSNNNLRISAKYGPSNMHLIVSTWLDTFRNVMSVAAKSTPDSLFNSKRMESIEEFSKPLVHAKFNLIYDMPFVQEGLRIVAKKINWILPFGLMVKGYKDMSMAPLTRALFLLSLVDSYFPKGTATEGSMKALTAYFRELVRTIDNSAFVPITEVNATPRTAYEVRVSSAIVHQNPYVTDTKAGMVAERVRTDAEILTSGALLSSGALSAHATAVAKLLSSNEPDDVSSRARARVAEHASNTWETIQASTTPTQVVEALVTAGFTSTHCGILERVVVDYFTRLRSTANSGPGRNDSLDYAQQVVGCVAIVGGVVFRLLLSYGFGLDYIRDYTTTISTLEPVYNELLSALGLADKGVEQTLKRSMAPRPYMNYISAARAALDDELLIVEKRTTGPGTHSAARESLLTWFDFRARDRWGVRIPDRDTTSTQVLAPITASLYSDDDLIAAASKLSFDALDAPPTQIIDDPSFAPYMLATVVLDAFNAILTSRFSADSVSQALRVLSWARDYGAGSIANVDGYRTKLTAIIASVSPFLQKDAPTPTMAHANNLEALLGELHSVVVAAIALIPERARMPVPERPSVKTSTFLAGLFLTAVYKRLETLVGHTAELTNNILGTASGIVSSIVTLNRFFNCRIMPVMGHYAVLIYPQSAQSAPFGRWRLVDVVDAVGSIYNEVSDLRADLRADVVTLKGDITSAAEALQECEALAVKTEGTRFGKLFNSLLTRHTQLARAQRGLAIRAGKLLGGSEAPGLKHVNTFLQRWGAISVMYQKATSGSTPEVNITSLANTLRHVWDEVQQERKATPPSRKFSNRDLGLAVERLMGGYPEVLDDDSNSTALTPKFNVDSWNSVNMDALRKRVTMPANIDSIRGNDSLATREYLKKEDLLAEIDAIFNNTK
What is the function of this protein?
Plays an essential role in cytoplasmic secondary envelopment during viral egress.  Interacts with the capsid via the large tegument protein/LTP and participates in its transport to the host trans-Golgi network (TGN) where secondary envelopment occurs.  Modulates tegumentation and capsid accumulation at the viral assembly complex.
What are the official names of this protein?
Inner tegument protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae inner tegument protein family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Host nucleus. Host Golgi apparatus, host trans-Golgi network.
Protein: PCDA8_PANTR
Sequence: MVYHWRGDLGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHRDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDNPPVFRVKEQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSFHDYFMLDVNSKNDENKLVELVLRKSLDREDAPAHDLFLTATDGGKPELTGTVQLLVTVLDVNDNAPNFEQSEYEVRIFENADNGTTVIKLNASDRDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLDFEQENFYKIRIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERSLSSYVSVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGSASELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQAPKASSRQSAGVVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQSQRVCSGEGPPKTDLMAFSPCLPPDLGSVDVGEERDLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPANSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin alpha-8, PCDH-alpha-8.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RS13_BRUA1
Sequence: MARIAGVNIPTNKRVNIALQYIHGIGPKFAREIVTKVGIADDRRVNQLSDAEVLQIREAIDADYQVEGDLRREVSMNIKRLMDLGCYRGLRHRRSLPVRGQRTHTNARTRKGPAKAIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: SYA_LACAC
Sequence: MKKLNSSEFRQMFLDFFKEHGHMIMPSASLIPQDDPTLLWINSGVATMKKYFDGSVVPKNRRITSSQKSIRTNDIENVGKTARHQTFFEMLGNFSVGDYFRDEAIPWAWEFLTSPKWLGLPKEKLYCTVYPKDEDSFNVWVKAGMPADHIVKLEDNFWDIGEGPCGPDTEIFYDRGQENNDVAEDDPENFPGGENARYLEIWNIVFSQYNHLPNGKYVDQPHKNIDTGMGLERVLSILQDAPTNFETDLFLPIIHATEEMTDGKKYGENDEDTTAFKIIADHVRAVSFAIADGALPSNSGRGYVLRRLIRRADLNGQRLGIKGAFLYKLVPVVGKIMESHYPEIMDQRGFIENVIQNEEERFQSTLDTGLTLLDDLIEKAKNSDDKTISGKDAFKMFDTYGFPYELTFESAQDAGLKVDKKGFDAEMQAQKDRARKARGDLQSMGRQDVTLMNIKDKSEFEYGVYEEPHAKLIDIVVDDKLVDKANGEHATLVFDKTPFYAERGGQVADHGGIYNQDGELVAKVTDVQHAPNDQNLHFVDLILPMEKGQEYVLKIDKERREGLRHSHSATHLLHAALRQVLGEHTHQAGSLVDPDYLRFDFTAMEPMTPRELKSVEELVNQKIWDAIQVKTTITTPEEGEKMGALALFDGKYGDKVRVVQMSDFSSEFCGGTHVDNTDQIGIFKITSESAVGAGMRRIEAVTSKKAYEYLANRSSLLDDIQEVVKATKPENIVDKIDSIENELRDSQKQVEALTKKINQAKAGEIFDNVKQAGDLTVIAAIADVNGMNDLRELADNWKSGNKSDVLVLAAENDGKANMIISLDQRALDKGLKAGDLIKKAAPLFGGGGGGRPNMAQAGGKKPEGLNDAIKAVIDEISNN
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF27_CYAPA
Sequence: MEINKKKILVVDDEISIRRILETRLSMIGYEVVTAADGEEALTIFQLEHPNLVVLDVMMPKLDGYGVCQELRKESDIPIIMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRSLLRRTENPTLSTTSTNGENLQIGFLKIDINKRQVFKNGERIRLTGMEFSLLELLISKMGEPFSRAQILQEVWGYTPERHIDTRVVDVHISRLRSKLEENPSNPDLILTARGIGYLFQNTSN
What is the function of this protein?
Probable promoter-specific protein mediating the interaction between DNA and RNA polymerase.
What are the official names of this protein?
Probable transcriptional regulator ycf27, OmpR-like protein.
What are the subcellular locations of this protein?
Plastid, cyanelle.
Protein: KGUA_EHRRW
Sequence: MNNNLKSRGIMLVMSSPSGGGKTTISQLLVNELQGEIIRSVSVTTREPRNEEVEGKDYFFVTEDEFHHLCNTNQMLEYAKVFGNYYGIPRRFVMDNINNGISILFSIDWQGAFKLIDIMSEHVVSVFILPPSMEELKRRLYNRSGESDMINQRLKEAAFEISHCYRYNYIIVNHNIEESVQQIKSIFIAEKLKTHRKMFLEQVVKSYYI
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.