PharMolix/UniProtQA huggingface dataset:
Protein: RPOC_CLOD6
Sequence: MFELNNFESIKIALASPEKIRQWSRGEVKKPETINYRTLKPEKDGLFCERIFGPQKDWECHCGKYRRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPMSHIWYFKGIPSRMGLLLDMSPRSLEKILYFASYVVVDPGETGLNEKQLLTEKEYRTALEKYGYTFTVGMGAEAVKTLLQNIDLEQQSKDLRAELKDSTGQKKVRTIRRLEVVEAFKKSGNKPEWMILDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLELGAPDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKFYQCGLPKKMALELFKPFVMDKLVKEGYAHNIKSAKSIVEKVKPEVWDVLEDVIKSHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADFDGDQMAVHVPLSVEAQAEARFLMLSVNNILAPKDGSPITTPSQDMVLGCYYLTIEAQDGAKGTGMVFKDFNELLLAYYNKSVHLHALVKLKVTLEDGRSSLVESTVGRFIFNENIPQDLGFVDRKENPFALEVDFLADKKSLGKIIDKCFRKHGNTETAELLDYIKALGFKYSTLGGITVAVDDMSVPEEKKVFIAEAEAKVDKYEKAYRRGLISDEERYEKVIETWTETTDKVTDALMGGLDRLNNIYIMAHSGARGSKNQIRQLAGMRGLMANASGKTVEIPVKSNFREGLSVLEYFTSSHGARKGLADTAIRTAESGYLTRRLVDVSQDVIVREIDCGTEDTTEIYAIKEGNEVIEEIYDRIVGRYTIDPILNPETGEVIVEADSMIQEDEAETIVALGIEKIRIRTVLNCKTNHGVCSKCYGRNLATGKEVNIGEAVGIIAAQSIGEPGTQLTMRTFHTGGVAGADITQGLPRVEELFEARKPKGLAVITEVSGRVEIDETGKRKEVNVIPEEGETQTYVIPYGSRLKVKQGQMLEAGDPLTQGFINPHDIVRVNGVKGVQEYIVKEVQRVYRLQGVDVNDKHIEVIVRQMLSKVKVEDPGDTDLLPGGYEDVLTFNECNKDAIDKGLRPAVAKRVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKEDHLIGLKENVILGKLIPAGTGMKKYRNIAVEKIED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: DNLJ_CLOD6
Sequence: MSVKDEINKLIETINYHNERYYNQDSPEISDYEYDKLMKELISLEEEHPELKRIDSPTNRVGGKPLDKFNQIVHKTPMLSLSNAFSEQDLRDFDKRVQEYVGENVEYVVEFKIDGLSVGLTYNNGEFEKGATRGDGVVGEDISQNLMTVKSIPLKINDKKELIVRGEVYISKDNFRKVNEQQEEQEQPLFANPRNLAAGSLRQLDPKLTAKRPLDIFVFNMENIEEYDLESHSESLEYLEKLGFSVSQSYKVCKSIDEVIEHIEYWTDNRGNLDYEIDGMVIKVNNIKQRDEMGYTAKSPRWAIAYKFPAEKKKTKIVDIIVEVGRTGTITPSAILEPVRLAGTTVSRATLHNEDYIREKDIKINDTVLVQKAGDIIPQVLEVIKEERTGDEIDFKMPEKCPVCSEPTIRLEGEAAVKCINMSCPAQIRRGIIHFVSRDAMNIDGLGESIITLLLNEKIIQDVSDLYYIKKEDVVDLERMGEKSADNLINSIEKSKENDLWRLINGLGIKFIGVKAAKILAYNFKDLDEVISATSEQLEELEEFGSIMANSVVEFFKEDKNMNVINKLKNVGVNTKSLDNTGEKVEKIFEGMKIVLTGTLPTLKRNDAKEMIEKRGGKATSSVSKSTTFVLAGEEAGSKLTKANDLGIKVIDEERFLELLKLSSKDEVKAVLES
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: DUT_VACCP
Sequence: MFNMNINSPVRFVKETNRAKSPTRQSPGAAGYDLYSAYDYTIPPGERQLIKTDISMSMPKICYGRIAPRSGLSLKGIDIGGGVIDEDYRGNIGVILINNGKCTFNVNTGDRIAQLIYQRIYYPELEEVQSLDSTNRGDQGFGSTGLR
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: TNMT1_PAPBR
Sequence: MGSIDEVKKESAGETLGRLLKGEIKDEELKKLIKFQFEKRLQWGYKSSHQEQLSFNLDFIKSLKKMEMSGEIETMNKETYELPSEFLEAVFGKTVKQSMCYFKHESATIDEAEEAAHELYCERAQIKDGQTVLDIGCGQGGLVLYIARKYKKCHVTGLTNSKAQVNYLLKQAEKLGLTNVDAILADVTQYESDKTYDRLLMIEAIEHMKNLQLFMKKLSTWMTEESLLFVDHVCHKTFAHFFEAVDEDDWYSGFIFPPGCATILAANSLLYFQDDVSVVDHWVVNGMHMARSVDIWRKALDKNMEAAKEILLPGLGGSHEAVNGVVTHIRTFCMGGYEQFSMNDGDEWMVAQLLFKKK
What is the function of this protein?
N-methyltransferase with a strict substrate specificity for (R,S)-tetrahydropalmatine or (R,S)-stylopine.
What are the official names of this protein?
(S)-tetrahydroprotoberberine N-methyltransferase 1, PbTNMT1.
What is the protein family that this protein belongs to?
Belongs to the CFA/CMAS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOI_MYCTO
Sequence: MANTDRPALPHKRAVPPSRADSGPRRRRTKLLDAVAGFGVTLGSMFKKTVTEEYPERPGPVAARYHGRHQLNRYPDGLEKCIGCELCAWACPADAIYVEGADNTEEERFSPGERYGRVYQINYLRCIGCGLCIEACPTRALTMTYDYELADDNRADLIYEKDRLLAPLLPEMAAPPHPRTPGATDKDYYLGNVTAEGLRGVRESQTTGDSR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PSD_PSEFS
Sequence: MKKQLFILSQYLLPHHLLSRLAGCIAECRVRWFKNAFTAWFAKRYQVDMSQALVEDLTAYEHFNAFFTRALKDGARPLDQTPGAVLSPADGAVSQLGPIEHGRVFQAKGHSFSVLELLGGDAALSAPFMGGDFATVYLSPKDYHRVHMPLAGTLREMVYIPGRIFSVNQTTAENVPELFARNERVACIFDTERGPMAVVLVGAMIVASIETVWAGLVTPPKRELKTFRYDEAARAPIHLEKGAELGRFKLGSTAIVLFGPDQVKWAEELVAGSPVQMGQGIAAPKA
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ADF_BRANA
Sequence: EDNCKLKFLELKKRIFRFIIFRIDGQQVVVEKLGNPQETYDDFTASLPADECRYAVFDFDFTTNENCQKSKIFFIAWSPDSSRVRMKMVYASSKDRFKRELDGIQVELQATDPSEMSFDIIKSRAL
What is the function of this protein?
Actin-depolymerizing protein.  Severs actin filaments (F-actin) and binds to actin monomers (By similarity).
What are the official names of this protein?
Actin-depolymerizing factor, ADF.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
Protein: EFG_ECOLC
Sequence: MARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVNQIKTRLGANPVPLQLAIGAEEHFTGVVDLVKMKAINWNDADQGVTFEYEDIPADMVELANEWHQNLIESAAEASEELMEKYLGGEELTEAEIKGALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPAERHASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKAARERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCDPDAPIILERMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTDEESNQTIIAGMGELHLDIIVDRMKREFNVEANVGKPQVAYRETIRQKVTDVEGKHAKQSGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGIQEQLKAGPLAGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEGFKKAKPVLLEPIMKVEVETPEENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMFGYATQLRSLTKGRASYTMEFLKYDEAPSNVAQAVIEARGK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_SPHAL
Sequence: MTGPVPDARVIDGKAFAAGLRARIADAVPAFRAATGRAPGLAVVLVGDDPASAVYVGSKGKATVAAGMASFEHRLAATATQDEVEALLRQLNADEAVDGILLQLPLPGHLDEQAAVATIDPDKDVDGLTPVSAGRLALGIPGMVPCTPYGCLLLLQDRLGDLSGKDAIVIGRSILVGKPMGQLLLGANCTVTMAHSRTKDLPALVRRADIVVAAVGRAEMVKGDWIKPGAIVIDVGINRLPPADGAAKGRLVGDVDYAAALGVADAITPVPGGVGPMTIACLLRNTLVAAHRRAGLADPEGF
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: CYB6_EUGGR
Sequence: MSRVYDWFEERLEIQAIADDVSSKYVPPHVNIFYCLGGITFTCFIIQVATGFAMTFYYRPTVTEAFLSVKYIMNEVNFGWLIRSIHRWSASMMVLMMILHVCRVYLTGGFKKPRELTWVTGIILAILTVSFGVTGYSLPWDQVGYWAVKIVTGVPEAIPLIGNFIVELLRGSVSVGQSTLTRFYSLHTFVLPLLTATFMLGHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL13_CERS1
Sequence: MKTFTATPADIEKKWILIDAEGVVLGRLATIVANILRGKNKPTFTPHMDMGDNVIVINADKVQMTGNKRADKRYYWHTGHPGGVKFRTAEQVLEGAHPERVVLKAVERMISRNSLGRQQMTNLRVYAGAEHPHEAQQPTVLDVKSLNPKNTRSA
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: ANXA2_BOVIN
Sequence: MSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNEQRQDIAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIVSDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKKKYGKSLYYYIQQDTKGDYQKALLYLCGGDD
What is the function of this protein?
Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids.  It binds two calcium ions with high affinity.  May be involved in heat-stress response.  Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9.
What are the official names of this protein?
Annexin A2, Annexin II, Annexin-2, Calpactin I heavy chain, Calpactin-1 heavy chain, Chromobindin-8, Lipocortin II, Placental anticoagulant protein IV, PAP-IV, Protein I, p36.
What is the protein family that this protein belongs to?
Belongs to the annexin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane. Melanosome. Note=In the lamina beneath the plasma membrane.
Protein: RM27_DICDI
Sequence: MSFFRGTFSTSSLFINTVDSVTKRFATKKSAGSTKNGRTSQPKNLGLKKSGNQLVYPGEIIIRQRGTEFHPGTFVGMGKDHTIFSKTIGLVSFSKEPKFPGSKKTRRFISVAPLYTNNININTNIDTSIDTNVNNNNSNINI
What are the official names of this protein?
Probable 39S ribosomal protein L27, mitochondrial, L27mt, MRP-L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: S10AG_HUMAN
Sequence: MSDCYTELEKAVIVLVENFYKYVSKYSLVKNKISKSSFREMLQKELNHMLSDTGNRKAADKLIQNLDANHDGRISFDEYWTLIGGITGPIAKLIHEQEQQSSS
What is the function of this protein?
Calcium-binding protein.  Binds one calcium ion per monomer (PubMed:17030513).  Can promote differentiation of adipocytes (in vitro) (By similarity).  Overexpression in preadipocytes increases their proliferation, enhances adipogenesis and reduces insulin-stimulated glucose uptake (By similarity).
What are the official names of this protein?
Protein S100-A16, Aging-associated gene 13 protein, Protein S100-F, S100 calcium-binding protein A16.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.
Protein: SIP3_YEAST
Sequence: MSVHGRDPKKRQLRLISVAFKEASIDSPSFRASVNFFQTRVDALEDWIEKTVDFFDQKYKVSFEDFRRAKETLLSQLLPPPALLSNGFVSNQSFTPRLIDSFNKDYYDFSMKLLQIVKGDDSSHSTALLELMTTAIEPYRNVRKNFDFYQGKYDSMLASYQAIRISKTSLEPSSIKSDALQLFEVQKNYLKASLDLISAISAVKLSLDKFILESMKVLKSRSIFITKDSGRKIDLSPCINEYLDNYAIWVENSIEGSKVLDSDISNAKKQAYRYTLKRITPSSDTSDYNIRSIHSSKLLSKDTQVPPKSPEKSGWLYMKTQVGKPTREIWVRRWCFLKNAVFGMFLLSPSKTYVEETDKFGVFLTNVRYDPEEDRKFCFEVKIFGNKVTEAHDNMSKDITLVFQTSNYLDLKSWLIAFEATKKYVMSIQHDSLEYELAFKRFSPKFFEFASSTTTSIDQLITTFDKETESLYETLNCSISEYDILTLGEEKVFQFQMPTTPISTKMTQLAILSNFLTKGSWFPNAVLANIWGTTDWSEYTILPGKGKKPSSLLTIDGKRLPIRNSTIYPQYYSNELKVLDLQFKSLVFSPDQRLEKLPEELLLFKFEALWCPNKKQKFSATCFCTKDYIYCYMNSMEFICLTKISLSEIVSVEADRSSKKTLKLYDASGLQMKAIVLFSDYKLIASKLQYLLENKAIKNPNSNEEILVKFEQMEKESQEKKQEELYKIEQENSFDRKATSVSKIIKSRVTFWEMSDDASTLLNRLKKLQTEYSITYNHEYEISSKGLAHILFGDKSNAFPKCLFLARKDGEEHGKRFWYKNKDINGKSQLVRKIPFRLDMTGNFLNTGKYHRDKESKMIFATQRIVKIVDNKYYEVDLDPFFVKVPFCHLLKLSIKFVITESYDVDNHLEIKLNMTASSSSLHVLYKLEYIDSRTGKTIEKLSLAEIICQTWALKFAHSEFLLIRRVLRYYLEKIGKHGKVIKAIKLCGILGVLSNKSEEPATEKNGNSKESESMQYDIRYSCTILFLVFIKLMVYRVTNLTFVFFRILIGILLLCAEKFSRINRMMVVGLLASIMINILLSEKASVPYWSIKRAEKLFHDRLGSDKFTMQRAIYISDSDLLSSQLSVPSNNPIFEKFSEDNFNKDYQYSETRKQLAMRRNELLIELRILQDMEKQLVHDDYEKFLLEEVNKCSMVSIEMTDLWFNDTQLQNYCSICNEELEKLRPPIT
What is the function of this protein?
May be involved in sterol transfer between intracellular membranes.
What are the official names of this protein?
Membrane-anchored lipid-binding protein SIP3, Lipid transfer protein anchored at membrane contact sites 3, SNF1-interacting protein 3.
What is the protein family that this protein belongs to?
Belongs to the SIP3 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Note=Localizes to puncta in the cell periphery representing cortical endoplasmic reticulum (cER)-plasma membrane (PM) membrane contact sites.
Protein: DPO41_MYCBO
Sequence: MESRWVLHLDMDAFFASVEQLTRPTLRGRPVLVGGLGGRGVVAGASYEARAYGARSAMPMHQARRLIGVTAVVLPPRGVVYGIASRRVFDTVRGLVPVVEQLSFDEAFAEPPQLAGAVAEDVETFCERLRRRVRDETGLIASVGAGSGKQIAKIASGLAKPDGIRVVRHAEEQALLSGLPVRRLWGIGPVAEEKLHRLGIETIGQLAALSDAEAANILGATIGPALHRLARGIDDRPVVERAEAKQISAESTFAVDLTTMEQLHEAIDSIAEHAHQRLLRDGRGARTITVKLKKSDMSTLTRSATMPYPTTDAGALFTVARRLLPDPLQIGPIRLLGVGFSGLSDIRQESLFADSDLTQETAAAHYVETPGAVVPAAHDATMWRVGDDVAHPELGHGWVQGAGHGVVTVRFETRGSGPGSARTFPVDTGDISNASPLDSLDWPDYIGQLSVEGSAGASAPTVDDVGDR
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII (By similarity).
What are the official names of this protein?
DNA polymerase IV 1, Pol IV 1.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 4HBT_PSEUC
Sequence: MARSITMQQRIEFGDCDPAGIVWFPNYHRWLDAASRNYFIKCGLPPWRQTVVERGIVGTPIVSCNASFVCTASYDDVLTIETCIKEWRRKSFVQRHSVSRTTPGGDVQLVMRADEIRVFAMNDGERLRAIEVPADYIELCS
What is the function of this protein?
Hydrolyzes 4-hydroxybenzoate-CoA, and to a lesser extent benzoyl-CoA and 4-chlorobenzoate-CoA.  Not active against aliphatic acyl-CoA thioesters, including palmitoyl-CoA, hexanoyl-CoA and acetyl-CoA.
What are the official names of this protein?
4-hydroxybenzoyl-CoA thioesterase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.
Protein: CSN5_CRYNJ
Sequence: MASTARKTFEINNNVQVVDPSAAIFQYSREEEKLLDDEAPWRTDPHYFHTVKISAVALIKMVTHARSGGIYEIMGIMYGKVRDGTFWIMDVAALPVQGTETRVNAGNEAMEYMVNFQTANAEAGKGELLRGWYHSHPGYGCWLSGIDVNTQLNNQKFNDPYLAVVIDPNRTVSAGKVEIGAFRTYPEGYTPPATGNSQYQSIPMDKIEDFGVHANAYYPLKVEIYKSKLDEKMLDLLWNKYWVATLSSNSLVSNLEYSTSQVQDLNAKLRAASQSISNSSSKLKLKPTQPTTKGKETTEGSDKKLKKGEKEFSGVEEEETPLNKVTQESSRITSEAENGIISQLLKEKLFNTPLTQSVDDKSAQATVQGRY
What is the function of this protein?
Catalytic Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes.
What are the official names of this protein?
COP9 signalosome complex subunit 5.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family. CSN5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MURU_PSEPK
Sequence: MKAMILAAGKGERMRPLTLHTPKPLVPVAGQPLIEYHLRALAAAGVTEVVINHAWLGQQIEDHLGDGSRFGLSIRYSPEGEPLETGGGIFKALPLLGDAPFLLVNGDVWTDYDFARLQAPLQGLAHLVLVDNPGHHGRGDFRLVGEQVVDGDDAPGTLTFSGISVLHPALFEGCQAGAFKLAPLLRQAMAAGKVSGEHYRGHWVDVGTLERLAEAESLIGERA
What is the function of this protein?
Catalyzes the formation of UDP-N-acetylmuramate (UDP-MurNAc), a crucial precursor of the bacterial peptidoglycan cell wall, from UTP and MurNAc-alpha-1P (PubMed:23831760, PubMed:25767118).  Is involved in peptidoglycan recycling as part of a cell wall recycling pathway that bypasses de novo biosynthesis of the peptidoglycan precursor UDP-MurNAc (PubMed:23831760).  Plays a role in intrinsic resistance to fosfomycin, which targets the de novo synthesis of UDP-MurNAc (PubMed:23831760).  Is not able to use GlcNAc-alpha-1P and GalNAc-alpha-1P as substrates (PubMed:23831760).  Cannot accept other nucleotide triphosphates (ATP, CTP, TTP, or GTP) than UTP (PubMed:25767118).
What are the official names of this protein?
N-acetylmuramate alpha-1-phosphate uridylyltransferase, MurNAc-1P uridylyltransferase, MurNAc-alpha-1P uridylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the nucleotidyltransferase MurU family.
Protein: MIAA_ACTPJ
Sequence: MNKKPLAIFLMGPTASGKTDLAIALRQTLPVEVISVDSALIYKGMDIGTAKPSKAELELAPHRLIDILDPSESYSAMNFREDALREMAEITASGRIPLLVGGTMLYYKALLEGLSPLPSADPEIRAEIEAKAEQIGWSGLHRELLAIDPIAGKRINPNDSQRINRALEVFYITGKTMTELTAQQGDSLPYNVLQFAIAPQDRAVLHQRIEQRFYKMMELGFQQEVEKLRARSDLHKDLPSIRCVGYRQMWEYLDGDISLDEAIYKGICATRQLAKRQITWLRGWNSEITWLDSLDPTSSKLKMIEKIAQNSIKL
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RPOC_RHOCS
Sequence: MNELMNIFGQPQGPQSFDQIRISIASPERIRSWSFGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMKYRGIICEKCGVEVTLSKVRRERMGHIELASPVAHIWFLKSLPSRIGLLLDMTLKDLERILYFENYVVIEPGLTDLKLHELLSEDQLLDKQDKFGEDAFTAKIGAEAMKDLLANLDLIEEKATCREELKETASEAKRKKLVKRLKLIEAFLGPSQEVEDVAAYERFEGYKERIERPDARPLFKIFPDATRPEWMILEVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELKAPDIIVRNEKRMLQEAVDALFDNGRRGRVITGANKRPLKSISDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKKMALELFKPFIYAKLELYGLASTIKAAKRMVEKERPEVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPTLIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQLEARVLMMSTNNILSPASGRPIIVPSQDIVLGLYYITMELPGMVGEGMAFGTIGEIEHALASKAVSLHAKIQCRYKTVDDEGNPITVRVTTTPGRMLLSEILPRHKAIKFDLINRLLTKKEIGNIIDVVYRHCGQKETVIFADRLMKLGFSNAFKAGISFGKDDMVIPAEKEILIREAQDRVKEYEQQYLDGLITQGEKYNKVVDVWSETTEKVASAMMKVIEQPKPGFGVNSVYMMAHSGARGSAAQIKQLAGMRGLMAKPSGEIIETPIISNFKEGLTVLEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDAIIVENDCGTTRGITMKAVIDGGEIVVPLGERILGRTVSVDIIHPLTGEMLVAAGDMITEREVEVIERAGIDSVHIRSVLTCETRDGVCAQCYGRDLARGTRVNMGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQRGAEQSFIEATLDAKVMVKNRNLVMNSEGVPVVMGRNCELALLDEQGRERARHRVPYGAKLNKALAADGAMIKKGDRLAEWDPYTLPILTEREGIANYVDLVEGVSVREVVDEATGISSKVVTDWRQQPRGADLRPRITLRDETGEVVKLPNGLEARYYMSVDAILSVENGARVRAGDVLARIPRESSKTRDITGGLPRVAELFEARRPKDFAIISDIDGRVEFGKDYKTKRRIVVRNDETGEEKEYLIPKGKHISVQEGDYVQKGDLLMDGNPVPHDILAVMGVESLANYLINEIQDVYRLQGVKINDKHIEVIVRQMLQKVEITDPGDTTLLAGEQVDRTEFEEENRLVQQRMNEGEQDLRFAIAKPVLQGITKASLQTRSFISAASFQETTRVLTEAAVQGKVDNLEGLKENVIVGRLIPAGTGSVVNRLKQIAAERDKALQLADGVDETPALADGGEAAA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: CSCLE_ARATH
Sequence: MNRNFSPAAMPPISSMTIDNSFSPPPSSGDLPEIPDAWYGNIQYLLNISVIGLLCCVSIFLFVKLRSDHRRMPGPSALFSKLLAVWKATCREIARHCGADAAQFLLIEGGSFVLLFSIAVLAVSVMLPLNLYAGTALLSDELSKTMITHIQKGSALLWLHFVFVVIVVVISHFGIAAIEARLKFTRFRDGNGNISDPNANSTAVFTIMVQGLPKNLGSDRVEFEDCFRLKYPGKVYKFIVPMDLCALDDLATELVRVRDEITWLVAKMDSRLLPDEYENVGDNGLVFCVCSLWVRVKVLWSQITERFGFTDDEKLRKLQELRADLESQLAAYKEGRAQGAGVAFVMFKDVYTANKAVQDFRNERSRRTGKFFSVTELRLQRNQWKVDRAPLATDIYWNHLGLTKVALIVRRVIVNTILLLILVFFSSPLALISALVSAGRIFNAEALDSAQYWLTWVQTSGWIGSLIFQFLPNVFIFVSMYIVIPSALSYLSKFERHLTVSGEQRAALLKMVCFFLVNLIILKALVESSLESALLKMSRCYLDGEDCKRIEEYMSPSFLSRSCVSALAFLITSTFLGISFDLLAPIPWIKKKIQKFRKNDMLQLVPEQNEEYALENQEPSSNLETPLLPENMFESPRFGDIEPMSQDLSEYPISRTSPIPKQKFDFAQYYAFNLTIFALTMIYSSFAPLVVPVGAVYFGYRYIVDKYNFLYVYRVRGFPAGNEGKLMDTVLCIMRFCVDLYLVSMLLFFSVKGDSTKLQAIFTLGVLVMYKLLPSDTDRYHPALLRSIQTVDSIIDGPVDYEAYSHPNFDWDTYNNR
What is the function of this protein?
Acts as an osmosensitive calcium-permeable cation channel.
What are the official names of this protein?
CSC1-like protein At4g35870.
What is the protein family that this protein belongs to?
Belongs to the CSC1 (TC 1.A.17) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYQ_BRADU
Sequence: MTEPVAAEVGRDFIRDIIQADLDQAKYREIVTRFPPEPNGYLHIGHAKSIALNFGIAQEFPGRCHLRFDDTNPVKEEQEYIDSIQADVHWLGFDWGKNLFFASDYFDRLYEWAETLIRDGLAYVDDQTQEEIRTSRGTLTEPGKNSPFRDRSVDENLDLFRRMKAGEFPNGARVLRAKIDMAAGNINLRDPVLYRILHAHHPRTGNAWCIYPSYDYAHGQSDAIEGITHSICTLEFEDHRPLYDWFIEKLPVPSKPHQYEFARLNLTYTLLSKRVLTQLVREGHVAGWDDPRMPTMAGMRRRGVPPAALREFVKRIGVAKANSVVDVGMLEFCIREELNRTAQRRMAVLKPLKVVIENYPEGQTEELEAINHPDDPSAGTRKITFGRELYIEQDDFMENPPKKFFRLSPGNEVRLRYAYFVKCTGVIKNESGEVVELRCTYDPATRGGNAPDGRKVKATMHWLSAAASKPAEIRIYNQLFANPSPDASNFAADLNPQSLEILSNARVEASVAESNSTEPMQFERQGYFVRDKDSTPGKPVFSRTIGLRDTFAKEVAKG
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.