PharMolix/UniProtQA huggingface dataset:
Protein: RUVB_LACPL
Sequence: MDDDKLLSGDKADDEEASLEKSLRPQTLAQYIGQARVKHELGVYIEAARKREESLDHVLLYGPPGLGKTTLAMVIANEMQVNIRTTSGPAIEKPGDLVALLNELEPGDILFIDEIHRLPKIVEEMLYSAMEDFFVDIVVGQGPTAHPVHFPLPPFTLIGATTRAGMLSAPLRDRFGIVEHMAYYEVADLEDIVKRTADIFQTSIKPSGAHEIARRSRGTPRIANRLFKRIRDFAEVADQDAIDEAIVARSLTYLRVDDAGLDETDNKLLRTMLEYYDGGPVGLATIAANIGEETDTIAEVVEPYLLQIGFLKRTQRGRVVTIKGYQHLGFPYPENK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: DSBA_SALTY
Sequence: MKKIWLALAGMVLAFSASAAQISDGKQYITLDKPVAGEPQVLEFFSFYCPHCYQFEEVLHVSDNVKKKLPEGTKMTKYHVEFLGPLGKELTQAWAVAMALGVEDKVTVPLFEAVQKTQTVQSAADIRKVFVDAGVKGEDYDAAWNSFVVKSLVAQQEKAAADLQLQGVPAMFVNGKYQINPQGMDTSSMDVFVQQYADTVKYLVDKK
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA.  Acts by transferring its disulfide bond to other proteins and is reduced in the process.  DsbA is reoxidized by DsbB.  It is required for pilus biogenesis (By similarity).
What are the official names of this protein?
Thiol:disulfide interchange protein DsbA.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbA subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL30_HISS2
Sequence: MMAKTIKVTQVRSSIARLPKHKATLRGLGLRRINHTIELIDTPAIRGMINQVSYMVKVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: DZI1L_MOUSE
Sequence: MQYPAATAEGLSGPLSGAYTLPAFKFQPRRESIDWRRISAVDVDRVARELDVATLQENIAGVTFCNLDGEVCNHCRQPVDPVLLKVLRLAQLIIEYLLHCQDCLSASVAQLEARLQASLGQQQRGQQELGRQADELKGVREESRRRRKMISTLQQLLLQTSAHSYHTCHLCDKTFMNATFLRGHIQRRHAGMADVGKQKQEQPLGEVLEELRAKLKWTQGELEAQREAERQRQVQELEMARQREMEAKKKFDEWKEKERSKLYGEIDKLKQLFWDEFKTVANQNSTLEEKLKALQSYSMTESHLGSLRDEESEERLKHAQEVQALQEKMEVQKTEWKRKMKALHEERAAERRQLQEENERLHVSLSQDQKKAAAQSQRHINALRAQLQEQARLIESQEETIQTLSLRKVEEVQEMPKAVATEEDSSEEELEASLEERQEQRKVLAALRKNPTWLKQFRPILEDTLEEKLEGLGIKRDTKGISAQTVRRLEPLLRTQREQIARSFREFPSLREKLNKEVSSRVKQRWESTTQPDGQPPVKSQRVTLATREVRPKTRTLTVALPSKPAEPSTPTLQGHSSHGPGLTQVSTPIPRPRVHGPSSTPVSPGSGLSSTPPFSSEEEPEGDVVQRVSLQPPKVLPRSAAKPEDNWGWSDSETSEESAQPPGKGSGGLASSGTLVQSIVKNLEKQLETPAKKPSGGVNMFLRPNAALQRASTPARKSQLSEDESDVEISSLEDLSQDLGQKGKPKPLSHSKLPEKFDVSPWSSGSRPRIPGW
What is the function of this protein?
Involved in primary cilium formation (PubMed:28530676).  Probably acts as a transition zone protein required for localization of PKD1/PC1 and PKD2/PC2 to the ciliary membrane (By similarity).
What are the official names of this protein?
Cilium assembly protein DZIP1L, DAZ-interacting zinc finger protein 1-like, Protein warpy.
What is the protein family that this protein belongs to?
Belongs to the DZIP C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes to centrioles and to the distal ends of basal bodies.
Protein: ILVC_BORA1
Sequence: MKVFYDKDCDLSLVKGKTVAIIGYGSQGHAHALNLHESGVKVVVGLRKGGASWNKAANAGLEVAEVAEAVKRADVVMMLLPDENIAAVYRDEVHANIKPGAALAFAHGFNVHYGQVVPREDIDVIMVAPKAPGHTVRSTYSQGGGVPHLVAVYQDKSGAARDVALSYASANGGGRAGIIETNFREETETDLFGEQAVLCGGTVELIKAGFDTLVEAGYAPEMAYFECLHELKLIVDLIYEGGIANMNYSISNNAEFGEYETGPKVVTDETRKAMRQCLTDIQTGEYAKRFILENAAGAPTLTSRRRINAESQIEVVGAKLRAMMPWIAANKLVDKSKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: CMOB_PSEF5
Sequence: MIDLSPLARRLAGTPLATWANGLQAQLDAKMEKGHGDLERWQSALDALPKIQPSEIDLINGLRLDTDCDDATRAQMRTALMGLSPWRKGPFDLFGVHVDTEWRSDWKWSRVAPHLNLEGKRILDVGCGNGYYMWRMLGAGAHSVIGVDPNWLFFCQFQAVQRYLSEPSVWHLPFPFEDLPANLEGFDTVFSMGVFYHRRSPIEHLLALKDCLVKGGELVLETLVVEGDQHQVLVPEDRYAQMRNVWFLPSVPALELWLRRAGFSDVRCVDVSVTSIEEQRGTEWMKYQSLSDFLDPNDHSKTIEGLPAPMRAVIVAKK
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: ADA_DICDI
Sequence: MIENNKEITLDIIKLLPKAELHRHLDGSIRISTLLELAKEQNVELPTYDQNELAKLIHKDENCSGLVNFLEAFQYTCSVLQHAYAITRVFYEMCEDAVADGVSYLEIRFSPVLHTSFGLSLSEVMEAVCDGMAIAELNLPIKARIIVCGLRHLDPSISKDLAEITWRYRHKGAIAFDLAGPEDGFSSKHHKEAFSIIRNKGINCTLHSGEDSNWTSVADSIHHCGAHRIGHGIAIQQNEELLNHVVNRRIPIECCITSNYQIKAISNASEHPIRKYFDSGAIVSICCDNCTMSNITLSGEYKLAIDTFNFKVEEVIRLIDYSFASSFIDPPLKINIRRESFKKALKIFQTNGYDISGVIENKFYYFEEIGLDVELEIQNNLANNFSLGKNVIRNYPQITLELLENLPKSDLHCRFDGGVSIEQIWNEVQLLGIDKCEKSKQEFLKKLSSKHLACYANFKDFKEFKSLIQSSSHTPQTIRLSKEIINLLLQTPEQINRAFDDIIKVALKDKVQYLELMIRPNSHSRNGLTKEQVLALIIENKDKWEKSSSIKIGLVVFSSSTSDDPIETLDSARLAIANRNSGVIGFGIFGADPISPTESRHFSQTFSLLKENNFNLVQFAGKSDVESLISTIHCSGSTRLSGAFQSHKIPRLMSYLGNYSIPVEISLTEKLKSFTSDDLSFTTPIRHLLDGKCPVVICSFRSSLYPYSRSKMYYKIVKNAKLDFKQVVRLLKNPFAYNFQSHQQRIELVQQFNKLSKEYLNSVNINYSNIII
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine.  Plays an important role in purine metabolism and in adenosine homeostasis, and may thereby contribute to cellular signaling events (By similarity).
What are the official names of this protein?
Probable adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
Protein: RELA_STAEQ
Sequence: MNNEYPYSADEVLYKAKSYLSTSEYEYVLKSYHIAYEAHKGQFRKNGLPYIMHPIQVAGILTEMRLDGPTIVAGFLHDVIEDTSYTFEDVKDMFNEEIARIVDGVTKLKKVKYRSKEEQQAENHRKLFIAIAKDVRVILVKLADRLHNMRTLKAMPREKQVRISKETLEIYAPLAHRLGINTIKWELEDTALRYIDSVQYFRIVNLMKKKRSEREAYITNAINKIKNEMTKMNLSGEINGRPKHIYSIYRKMIKQKKQFDQIFDLLAIRIIVNSINDCYATLGLVHTLWKPMPGRFKDYIAMPKQNMYQSLHTTVVGPNGDPLEIQIRTHEMHEIAEHGVAAHWAYKEGKTVNQKTQDFQNKLNWLKELAETDHTSADAQEFMESLKYDLQSDKVYAFTPASDVIELPYGAVPIDFAYAIHSEVGNKMIGAKVNGKIVPIDYVLQTGDIIEIRTSKHSYGPSRDWLKIVKSSSAKSKIKSFFKKQDRSSNIEKGKFMVEAEIKEQGFRVEDILTEKNLEVVNEKYHFANDEDLYAAVGFGGVTSIQIVNKLTERQRILDKQKALNEAQEVTKSVPIKKDITTDSGVYVEGLENVLIKLSKCCNPIPGDDIVGYITKGHGIKVHRTDCPNIKNETDRLISVEWVKSKDSTQQYQVDLEVTAYDRNGLLNEVLQAVNSTAGSLIKVSGRSDIDKNAVINISVMVKNVNDVYRVVEKIKQLGDVYTVSRVWN
What is the function of this protein?
In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.  This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity).
What are the official names of this protein?
GTP pyrophosphokinase, (p)ppGpp synthase, ATP:GTP 3'-pyrophosphotransferase, ppGpp synthase I.
What is the protein family that this protein belongs to?
Belongs to the RelA/SpoT family.
Protein: AROK_METI4
Sequence: MLRHIVLVGMMGAGKTTVGLWLSKAKSIPFYDLDQLIEGKERATIPEIFASKGVEYFREQEREIVKQVAYSSPGIVATGGGTLLNPSNLWLLKRYGRLFYLQASLDLLWTRLKNKTDRPLLLGKEPKVILEKLLKEREVLYKQADIEIAVDGRTVEELGELLWSYWETMEKTDPR
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISZ_RHIL3
Sequence: MPLINLPDFANDLIAEFVERNAERIDTPVIQPAEPFLDIAGEDLRRRIFMTESETGASLCLRPEFTIPVCLRHIETATGTPKRYAYLGEVFRQRRDGANEFYQAGIEDLGDIDLSNADARAIGDATGILARLLPGRHLAVTLGDQAVFEAVVQALGLPLGWQKRLIHAFGNMTQLEALLASLVSPQFVTGLDDDIARLVASGDEQALVAHLEREMQKTGYSTNAGRSALEIARRLKEKLILSETRLDDAAFHVLEEFLSLDVPLVNASAALSGFADAAGLKLGNALSRFNGRVAALSNAGVDLSCLDYRAAFGRPLDYYTGLVFEVTVEGSTAVLAGGGRFDRLLTFLGATDRIPAVGFSFWLDRIETERAAA
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BMP_TREPA
Sequence: MGRYIVPALLCVAGMGFAHAQSALQPIAEVNLFRREPVTLGQIKARISAIEKEMGKKLSTAERRQFMDSLIDEKLFAQAAEKAGIQVTDAEVNQYFNGMLSQQIGRAVTEAEFANYVKEKQNISLDQFMKQQNGMTMAEYKKFLKTQVSTQRYVAQKKADEFRNLKGPEDSQIRSYYELNKQAFFRPDTVKLFLISVPKGSGPAAAKAKAQEFVKKLKSSGVKATADIKSKANGAQAGYSAGEIYLGKTAVTATQLGLTMEALLEIFGMGVGAVSDVNETANDYQCFIVLKKEEAKILTLSDLVEPDKTVSLYEFIKNLLTSQIQQKALEDAIREVSAELRKSGTYKVFLADAELGKVLDW
What are the official names of this protein?
Basic membrane protein.
What are the subcellular locations of this protein?
Cell membrane.
Protein: PSAJ_CUSOB
Sequence: MRDFKTYLSVAPVLSTLSLGFFAGFLIEINRFFPDALTFPFFSF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid membrane; Single-pass membrane protein.
Protein: COBS_RHIE6
Sequence: MKIKDYAVDTARAVAFLSRLPMPPALFNGYDGRLGRLVRAFPFAGLLIGFVPAFALLLLLGLRADPLVAALVALAVQALVTGALHEDGLADTADGIGGGKSREQSLIIMKDSRIGTYGAIALILSFAIRAAALAAIVRHSSPLAAVLAIPAVAALSRGAITWHWQRLPPAKADGVAASTGQPDEAAMHFALVAAGLLAALLIWPAFGLWPLVASLLAAGAAGFVCTVFIRRRLAGHTGDTLGATQQICEIATLCALATAL
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GPMA_CAUSK
Sequence: MPVLVLLRHGQSQWNLENRFTGWVDVDLTAEGEAQARKGGELIKAAGINLDEAFTSVQTRAIRTGNLALDAAGQSFVPVTKDWRLNERHYGGLTGLNKAETAQKHGEEQVTIWRRSYDIPPPPLAPGGEYDFGKDRRYAGKDLPDTESLKTTLTRVLPYWETAIAPKLKAGETILVAAHGNSLRAIVKHLFDVPDDKIVHVEIPTGNPLVIDLDADLKPTGARYLDAARAQPLPAVG
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: GPMA_HAEIN
Sequence: MELVFIRHGFSEWNAKNLFTGWRDVNLTERGVEEAKTAGKKLLDKGYEFDIAFTSVLTRAIKTCNIVLEESHQLWIPQVKNWRLNERHYGALQGLDKKATAEQYGDEQVHIWRRSYDISPPDLDPQDPNSAHNDRRYANIPSDVVPNAENLKLTLERALPFWEDQIAPAMLSGKRVLVVAHGNSLRALAKHIIGISDAEIMDFEIPTGQPLVLKLDDKLNYVEHYYL
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: MSCL_ACISJ
Sequence: MGIAKEFREFAVKGNVIDLAVGVIIGGAFGKIVDSVVSDLIMPVVGLVFGKLDFSNLFIVLGSVPEGTPYTLEAIRKAGVPVLAYGNFITVAVNFVILAFIIFVMVKQINRLKRETPVEPPAPPATPEDIQLLREIRDSLKR
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AAEX_SALPK
Sequence: MSLFPVIVVFGLSFPPIFFELLLSLAIFWLVRRMLVPTGIYDFVWHPALFNTALYCCLFYLISRLFV
What are the official names of this protein?
Protein AaeX.
What is the protein family that this protein belongs to?
Belongs to the AaeX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KAT5_ORYSJ
Sequence: MAARSELLRSAFGKASPSLGWFIVNPHRYSYRWWHMFLIMLVLYSAWASPFELSMEKAASIALVVIRPSGRCLLRHRHCHILLRHLVTGKRQGLWGLLNLLRLWRLRCASKLFARVEKDVRFSYLWTRLIKLLCVTLFALHFAACIYLWMVFNYKIKELTWIGSQIHSFEDRSVWFCYTCAVYWSITTLATVGYGDLHATNIGEMLFSIAFMLFNMGLTSYIIGNITNLVVRETSNTFKMRDMVQWVSEFGSMNRLPEVMREQMLANGQLRFRTKEQLQHEHVKRIGPRGMVGEIGVMFSIPQPFTIRSRRLTQVVRISHIHLLQAVRPNTADGCIVFSNFILVSDFVEYLESLKVQTKEVAFVSGHL
What is the function of this protein?
Putative inward-rectifying potassium channel.
What are the official names of this protein?
Putative potassium channel KAT5.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. Plant (TC 1.A.1.4) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NU5C_TOBAC
Sequence: MEQTYEYAWIIPFIPLPVPMLIGAGLFLFPTATKSFRRMWAFQSVLLLSIVMVFSIYLSIQQINSSSFYQYVWSWIINNDFSLDFGYLIDPLTSIMSILITTVGIMVLIYSDNYMAHDQGYLRFFAYMSFFSTSMLGLVTSSNLIQIYIFWELVGLCSYLLIGFWFTRPVAANACQKAFVTNRVGDFGLLLGILGFYWITGSFEFRDLFEIFNNLIYNNEVDFLFVTLCAVLLFAGAVAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLLPLFRVIPYIMYLISVIGIITVLLGATLALAQKDIKRGLAYSTMSQLGYMMLALGMGSYRSALFHLITHAYSKALLFLGSGSIIHSMETIVGYSPAKSQNMGLMGGLRKHVPISKITFLLGTLSLCGIPPLACFWSKDEILNDSWLYSPIFAIIAWATAGLTAFYMFRIYLLTFEGHLNAHFPNYGGKQKTPFYSISLWGKNGVKKNSCLLTMNNNESTYFFAKTKYPIDKNGRKMTRPFMTIAHFEHKAVYSYPYESDNTMLFPIFVLGLFTLFVGSIGIPFNQEGGNLDILSKWLAPSINLLHQKSNNSMDWNEFLKDAVLSVSIAYFGIFIASFLYKPIYSSLKNFELINSFVKKGPKRILWDKIINGIYDWSYNRAYIDAFYTRFLVGGIRGLAEFTHFFDRRVIDGMTNGVGVISFIVGEGIKYIGGGRISSYLFLYLAYVSIFLLVYYLLFSTL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CSRA_KLEP7
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQAEKSQQSSY
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
Protein: ZN532_HUMAN
Sequence: MTMGDMKTPDFDDLLAAFDIPDMVDPKAAIESGHDDHESHMKQNAHGEDDSHAPSSSDVGVSVIVKNVRNIDSSEGGEKDGHNPTGNGLHNGFLTASSLDSYSKDGAKSLKGDVPASEVTLKDSTFSQFSPISSAEEFDDDEKIEVDDPPDKEDMRSSFRSNVLTGSAPQQDYDKLKALGGENSSKTGLSTSGNVEKNKAVKRETEASSINLSVYEPFKVRKAEDKLKESSDKVLENRVLDGKLSSEKNDTSLPSVAPSKTKSSSKLSSCIAAIAALSAKKAASDSCKEPVANSRESSPLPKEVNDSPRAADKSPESQNLIDGTKKPSLKQPDSPRSISSENSSKGSPSSPAGSTPAIPKVRIKTIKTSSGEIKRTVTRVLPEVDLDSGKKPSEQTASVMASVTSLLSSPASAAVLSSPPRAPLQSAVVTNAVSPAELTPKQVTIKPVATAFLPVSAVKTAGSQVINLKLANNTTVKATVISAASVQSASSAIIKAANAIQQQTVVVPASSLANAKLVPKTVHLANLNLLPQGAQATSELRQVLTKPQQQIKQAIINAAASQPPKKVSRVQVVSSLQSSVVEAFNKVLSSVNPVPVYIPNLSPPANAGITLPTRGYKCLECGDSFALEKSLTQHYDRRSVRIEVTCNHCTKNLVFYNKCSLLSHARGHKEKGVVMQCSHLILKPVPADQMIVSPSSNTSTSTSTLQSPVGAGTHTVTKIQSGITGTVISAPSSTPITPAMPLDEDPSKLCRHSLKCLECNEVFQDETSLATHFQQAADTSGQKTCTICQMLLPNQCSYASHQRIHQHKSPYTCPECGAICRSVHFQTHVTKNCLHYTRRVGFRCVHCNVVYSDVAALKSHIQGSHCEVFYKCPICPMAFKSAPSTHSHAYTQHPGIKIGEPKIIYKCSMCDTVFTLQTLLYRHFDQHIENQKVSVFKCPDCSLLYAQKQLMMDHIKSMHGTLKSIEGPPNLGINLPLSIKPATQNSANQNKEDTKSMNGKEKLEKKSPSPVKKSMETKKVASPGWTCWECDCLFMQRDVYISHVRKEHGKQMKKHPCRQCDKSFSSSHSLCRHNRIKHKGIRKVYACSHCPDSRRTFTKRLMLEKHVQLMHGIKDPDLKEMTDATNEEETEIKEDTKVPSPKRKLEEPVLEFRPPRGAITQPLKKLKINVFKVHKCAVCGFTTENLLQFHEHIPQHKSDGSSYQCRECGLCYTSHVSLSRHLFIVHKLKEPQPVSKQNGAGEDNQQENKPSHEDESPDGAVSDRKCKVCAKTFETEAALNTHMRTHGMAFIKSKRMSSAEK
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 532.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS20_PARD8
Sequence: MANHKSSIKRIRQTNARRLRNRYYAKTARNAMKVLRATEDKNEAQALFPKVCSMLDKLAKKNVIHKNKAGNLKSKLAKHVNALA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: IF1_BACCR
Sequence: MAKDDVIEVEGTVLETLPNAMFKVELENGHVVLAHVSGKIRMNFIRILPGDKVTVELSPYDLNRGRITYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G3P2_NOSS1
Sequence: MIRVAINGFGRIGRNFARCWLGRENTNIELVAVNDTSDPRTNAHLLKYDSMLGKLKNVDITADDNSITVNGKTIKCVSDRNPENLPWKEWEIDLIIEATGVFVSKEGATKHINAGAKKVLITAPGKNEDGTFVMGVNHHDYDHNLHNIISNASCTTNCLAPIAKVLNDKFGIIKGSMTTTHSYTGDQRLLDASHRDLRRARAAAINIVPTSTGAAKAVALVIPELKGKLNGVALRVPTPNVSMVDFVVQVEKRTITEEVNQALKDASEGPLKGILDYSELQLVSSDYQGTDASSIVDANLTLVMGNDLVKVMAWYDNEWGYSQRVLDLAELVAEKWV
What is the function of this protein?
Gap2 has a major role in carbon fixation as a component of the Calvin cycle.  Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NADP.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NADP to NADPH.  The reduced NADPH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase 2, GAPDH 2, NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_CHESB
Sequence: MSQSYELTAEARERVGKGSARAIRRNGKIPAVIYGDKQPPLSITLPYKEVFLRIHAGGFRTTVATIDLNGEKIQVLPKDYQLDPVRGFAMHVDFLRVGKNTVVTVNVPVHFINDEKAPGIKRGGVLNIVRHEVEFTCPANAIPDFIEVDLTGLDIGDSVHISAVKLPEGIVPTITDRDFTIATVAAPAGLKSEGAEGGEAEAGQAEEGEE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: FPG_STRAW
Sequence: MPELPEVEVVRRGLERWVAHRTVADVEVLHPRAVRRHTAGGEDFAHRLKGRRVGVPSRRGKYLWLPLETTDTAVLAHLGMSGQLLVQPHDCADERHLRIRVRFADALGTELRFVDQRTFGGLSLHDTTPDGLPDVIAHIARDPLDPLFDDAAFHEALRRKRTTVKRALLDQSLISGVGNIYADEALWRARIHYERPTAGFTRPRTAELLGHVRDVMNAALAVGGTSFDSLYVNVNGESGYFDRSLDAYGREGLPCRRCATPMRRRPWMNRSSYFCPKCQRAPRVTV
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.