PharMolix/UniProtQA huggingface dataset:
Protein: RTCA_PYRNV
Sequence: MAVRIDGSYGEGGGQILRTSIALSALLGKPVEIVNIRAKRANPGLQPQHLTGVSAAALLTDAEVEGAAKGSTRLFFKPKALKCGTFNIDIGTAGSISLVVQTLAPILLYAPCPTKLVITGGTDVAWAPPIDYMRFVFARYLTRFGARIAIELVKRGHYPRGGGKAVVQAEPAGRLRAVDSVEFGRPAKIAGVSHAVNLPPHVAERQARAAREALAKLGYAAEVEVEARNDGLGPGSGVVLWAESDVGNVVGGDALGERGKPAEEVGREAAEKLAAVLKAGASLDPHMADMVVLYMALAQGRSRLSTTEATMHLQTNIYIVEQFLPVKFKLERAGPRYIIEVEGVGYP
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBP3_ASPOR
Sequence: MTKRDLHNEGGDENKPRKKQKSEKQKKEKSAKSKSSAEQSLSYVQSPALGDVPQSEIEKFLTENSIKITDTSSENVMRPIISFSHLPPCKDDLYAPLSSFKSPTSIQSATWPLLFAGRDVIGIAETGSGKTLAFGLPCLKKIQDSAMTKQKPYRPLAVIISPTRELAMQIYDQLLKFSGSVGVRVACVFGGVRKEEQREALKTAGVVVATPGRLKDLQNDGSVDLGKVKYLVLDEADRMLDKGFEQDIKDIIRPMPVSKRQTIMFTATWPPSVRDLASTFMSSPVTVTIGGDPSADPRANTRIKQVVEVVKPHEKESRLVQLLNRSQRGVPEPEKVLAFCLYKKEAMRIERLLRTKGFKVAGIHGDLSQQERFRSLDAFKTGAATVLVATDVAARGLDIPSVKQVINVTFPLTVEDYVHRIGRTGRAGAEGHAVTLFTETDKAQSGALINVLRAAKQDIPEDLLKFGTTVKKKQHDAYGAFFKNVDTDKTATKIVFDD
What is the function of this protein?
ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis.  Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5. 8S rRNAs (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase dbp3.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PDHR_SALTI
Sequence: MAYSKIRQPKLSDVIEQQLEFLILEGTLRPGEKLPPERELAKQFDVSRPSLREAIQRLEAKGLLLRRQGGGTFVQSSLWQSFSDPLVELLSDHPESQFDLLETRHALEGIAAYYAALRSTDEDKDRIRELHHAIELAQESGDLDAESEAVLQYQIAVTEAAHNVVLLHLLRCMEPMLAQNVRQNFELLYARREMLPLVSTHRTRIFEAIMAGKPEEAREASHRHLAFIEEIMLDRSREESRRERALRRLEQRKN
What is the function of this protein?
Transcriptional repressor for the pyruvate dehydrogenase complex genes aceEF and lpd.
What are the official names of this protein?
Pyruvate dehydrogenase complex repressor.
Protein: RPIA_BRUME
Sequence: MDEARKLKIAAAAEALTYVKDGMRLGIGTGSTAEEFVRLLAEKVKGGFRVIGVPTSERTAKLCEELGVALTTLEETPHLDLTIDGADEVDGELSLIKGGGGALLREKIVAAASDSMIVIADQSKVVETLGRFPLPIEVNRFGLGATIRAIEAAAVKCGLAGPLNLRLKDGSPFLTDGGHYIVDASFGRIPDPKTLSDALFAIPGVVEHGLFIELARAAIIAGTDGIRTMNRS
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: APT_SALTO
Sequence: MTETHTTGVRGDSGRETAELVASRVLDVPDFPKPGVMFKDLMPLFSDGDAFREVIDDIVRYHGRDSFDTVVGIEARGFVVAAAIAYAAGVGVVPVRKAGKLPRVAYSASYALEYGEATLEVHQDAFTAGHRVLVVDDVLATGGTAEATLDLVERAGGTVAGFTVLLELGFLGGRERLTPRPVHALLTV
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLUB_BUCAP
Sequence: MTAKIQKILSDLGYGSRRFIECMIKCGKISINGEKAIIGQYLNKKNPGEILIDKKKIIVKRNKNLPKVLIYNKPIGEVCTRDDFQKRLTVFDKLPKLNLNRWVSVGRLDINTKGLLLFTNDGTLANKLMHPRSQIEREYNIRIFGEMNKNKINILRKGVKIIHGYVSFKEIVPLYDKKEGKNKWFKGILCEGKNREIRLMFKSIQCQVNQLIRVRYGNIILPKNLKEGQWMMLNSIFLKKLYNLINFDKEIINKKKN
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase B, 23S rRNA pseudouridine(2605) synthase, rRNA pseudouridylate synthase B, rRNA-uridine isomerase B.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RsuA family.
Protein: SLIK6_MOUSE
Sequence: MKLWTYLLYPSLLACLSLQSQSPMPSVRGSCDTLCNCEEKDGIMIINCEEKGINKLSQISVPPSRPFHLSLLNNGLTMLHTNDFSGLTNALSIHLGFNNIADIETGAFNGLGLLKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITIIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLTHLDLRGNQLQTLPYVGFLEHIGRILDLQLEDNKWACNCELLQLKNWLENMPPQSIIGDVICYSPPPFKGSVLSRLKKESFCPTPPVYEEHEDPSGSLLAITSSTSDSRLSSKNTSILKQPTKAPGLIPYLTKPSTQLPVPYCPIPCNCKVLSPSGLLIHCQERNIESLSDLQPPPHNPRKLILAGNIIHTLMKSDLTDYFTLEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLNKGMFLGLHSLEYLYLEYNAVKEILPGTFNPMPKLKVLYLNNNLLQVLPAHIFLGIPLTRVNLKTNQFTHLPVSNILDDLDFLIQIDLEDNPWDCSCDLVGLQQWIHKLGKGTMTDDILCTSPGHLDKKELKALNSDLLCPGLVNNPSMPTQTTYVIVTSPTVAADTASTLFSSLTDAVPLSVLILGLLIVFITIVFCAAGIVVFVLHRRRRYKKKKVEEQLRDNSPVHLQYSMYGHKTTHHTTERPSSSLYEQHMVSPMVHVYRSPSFGPKHLEEVEERNDKEGNDAKHLQRSLLERENHSPLTGSNMKYKTTDQSTDFISFQDASLLYRNILEKERELQQLGITEYLRKNLAQLQPEVEVNYPGAHEELKLMETLMYSRPRKVLVEQTKNEYFELKANLHAEPDYLEVLEQQT
What is the function of this protein?
Regulator of neurite outgrowth required for normal hearing and vision.
What are the official names of this protein?
SLIT and NTRK-like protein 6.
What is the protein family that this protein belongs to?
Belongs to the SLITRK family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: IGSF8_HUMAN
Sequence: MGALRPTLLPPSLPLLLLLMLGMGCWAREVLVPEGPLYRVAGTAVSISCNVTGYEGPAQQNFEWFLYRPEAPDTALGIVSTKDTQFSYAVFKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVELRVLPDVLQVSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRSTLQEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLGPGYEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAASARSRPLPVHVREEGVVLEAVAWLAGGTVYRGETASLLCNISVRGGPPGLRLAASWWVERPEDGELSSVPAQLVGGVGQDGVAELGVRPGGGPVSVELVGPRSHRLRLHSLGPEDEGVYHCAPSAWVQHADYSWYQAGSARSGPVTVYPYMHALDTLFVPLLVGTGVALVTGATVLGTITCCFMKRLRKR
What is the function of this protein?
May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function.  May regulate proliferation and differentiation of keratinocytes.  May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers.  May also play a role on integrin-dependent morphology and motility functions.  May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.
What are the official names of this protein?
Immunoglobulin superfamily member 8, IgSF8, CD81 partner 3, Glu-Trp-Ile EWI motif-containing protein 2, EWI-2, Keratinocytes-associated transmembrane protein 4, KCT-4, LIR-D1, Prostaglandin regulatory-like protein, PGRL.
Protein: DCTA_BURMA
Sequence: MKKPFYKVLYVQVIFAIVVGVILGHYYPSLAVDMKPLGDGFIKLIKMVIGPIIFCTVVTGIAGMQDMKKVGRVGGKALLYFEIVSTCALVLGLAATHILRPGVGFNIDPATLNGKEVASYAAKAHGQSSVDFLMHIIPNTMIDAFAQGEILQILLIALLFGSVLAHLGERGRVVTDFIDGITRVLFGIVHIVTKLAPIGAFGAMAFTIGKYGVGSLVPLLKLIGTFYLTSVVFVLVVLGAIARFTGFSIIRFVGYIKEELLIVLGTSSSEAALPQLMEKLEKAGCSRSVVGLVVPTGYLFNLDGTNIYMTMAVLFIAQATNIELTWMQQLTLLAVAMLTSKGASGVTGAGFITLAATLAVVPTIPLSGMVLILGIDRFMSECRALTNIVGNGVATVVVSAWEKELDRAKLRAALSGNGEAAAGEAARV
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NU1C_HELAN
Sequence: MIIDTTEVQAINSFSRLESLKEVYGIIWVLIPIFTPVLGITIGVLVIVWLEREISAGIQQRIGPEYAGPLGILQALADGTKLLFKENLLPSRGDTRLFSIGPSIAVISILLSYLVIPFGYRLVLADLSIGVFLWIAISSIAPVGLLMSGYGSNNKYSFLGGLRAAAQSISYEIPLTLCVLSISLLSNSSSTVDIVEAQSKYGFWGWNLWRQPIGFLVFLISSLAECERLPFDLPEAEEELVAGYQTEYSGIKFGLFYVASYLNLLVSSLFVTVLYLGGWNLSIPYIPVPELFDITKRGRVFGTIIGIFITLAKTYLFLFIPIATRWTLPRLRMDQLLNLGWKFLLPISLGNLLLTTSSQLLSL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic, NAD(P)H dehydrogenase subunit 1, NDH subunit 1, NADH-plastoquinone oxidoreductase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SPEA_GEOUR
Sequence: MERWSINDSAKIYNLNNWGADLFSINKKGNVCVHPSSNSKHSIDLRALVDDLIKRKIKPPILLRFMDVLQGRIASINRVFKNAIQENNYPAKYQTFYPIKVNQQRQVVEAIANFGKRYNIGLEVGSKPELVAGISFATGNNLPIICNGYKDTEYIEMVLSATKIGYDITLVVEKLFELEKIIELVKKTGVQPKLGIRVKLSSKGIGKWATSGGEDAKFGLRMSEIIAAIEMLEKHDLIKCVKLLHFHIGSQITKIDKIKTALIEGARIYAEMRKLGVGIEYLDIGGGLGVDYDGSKSSNFSSVNYSIEEYANDVIYQIKNICEDAGVECPNIISESGRATVAHYSVLVTNVLNTNTQNIMPDFEATLNEAEKLAPTVKKLEDIYKSIDRYSLREDYHDTLQLIQEAVSLFNLGYLTLNDRAMAEWLYGKIIRKINSIVEKIKPIPEELQNFQLSLRQTYFANFSLFQSVPDSWAIDQLFPIVPIQRLNQKPDVIASIADITCDSDGEITSFVGENGRTKFLPLHKIRKDEAYYIGFFLIGAYQEILGDMHNLFGDTNAVHITFNKKTGYIIDTVINGDATWESLKYVQYKGPEILKRVRDNLEKDVALRKISIEESSHFLELLDRTLLGYTYLGE
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: BST1_DEBHA
Sequence: MDSKSRGKSRLNRSILTLVSFFGLVLFYLTWYLYTRGLTGADSPGCRIVYMGPSYARITAFDESHTKFASKYSLYLYREQGRDPLPDENEGFKHLGGIPILFIPGNAGSYRQVRSIAAETSDIYFDHYLDQPDGLNPNAKNYDFFTADFNEDFTAFHGRTLLDQAEYLNEAIKFILGLYANSEHPPRSVVVLGHSMGGVVSRVMVSLPNYIPDSINTIITLASPHAAAPLTFDGDILKIYSAVDRFWFQGYDNKETDNTIAKIAKERLSKISLISITGGLLDSILPADYTTLGYLVPPTNGFTVYTTGIPGVWTPIDHLAIVWCAQLRRRVSNALLEIANFDSPDKTYSLEKRMEIMRKNFLSGFEDYTSQDKVAYDKPADHILLKADSQQINFVQEGQKLKVTPGKMPSPLNVFRLPSPKVSKVQFSLLSSMDIGELKSDNNEGYTQPTLLLCNTMDAIKEDANIIDFTNKETTEIVMFKCIDVRDDSNMIPRSAVGTYSLSESSIGGDKSPFYAIQYNSTILKQYDTVIVTGSLGMESNDNENFLLAELSDYNSSQFNIHEDLFSLMTRGAKFSLPLDKPLSMNIKIPGAWSSILAYKLKVSWPEDRETTEYIPVFRTFIRQWSNEPYEVKWHVNIEANNQVLLNMHGIAPYTPFKVKSKEEYGLNIEIWTDSIPDKSLTTIRLRIDLLNSLRLLVLRYRLATISFCVSIILLALVFQVKHYKETNKFPTFLYGLSCICSPWVFGSILFTLSILTPIMSIKPLQKFLNVIDPVVLQDSNEINLSLTDEFKLNSFFLGLEEKSLWFIGPVFFVMGLGIVSLTFYSLLVAGNVIASISRVLLKRLKLSQTEKKQPNPGKLWANRRIIGVLFVLLVIPIYMPYQFAYVVSCIIQSIQVIKILVADKTNKSILNYHLSLLMLMLWVLPINVPILVVFVHNMTINWTTPFSSHHNFLAILPVILLMERYSNSRTLPKMSQTKYKVTQAFLAYYVFYCLVYGIRHTYWIHHLFNLLCCWLLVLHYDAQDDTSDHVQ
What is the function of this protein?
Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
What are the official names of this protein?
GPI inositol-deacylase.
What is the protein family that this protein belongs to?
Belongs to the GPI inositol-deacylase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NU4LM_ANOGA
Sequence: MANMFLMFYLSMIMFLFGCMVFVSNRKHLLSTLLSLEYMVLSLFIFLFFYLNFMNYETYFSMFFLTFCVCEGVLGLSILVSMIRTHGNDYFQSFSILQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: MFS54_ALTAL
Sequence: MKEGVVTPPDSEKDLQNVEGSLNTEEEKAEEAHIQLSKGRFVLVLVGLVLAIFLASLDFTIISTAIPKITDEFHSLQDIGWYGSAFFITTAATTAHWGRLYTFFPLKWTYLTSIFFFELGSVICGAAPSSTALIIGRAICGIGAAGLFSGSYTIIAVLVPSADRPKYSGLMGASYGLASVVGPLIGGAFTSHVSWRWCFYINLPVGGVSCLFILLFFANEPPKSRPDWRGMLRQLDMLGLVLIVGAITCFILALQWGGVSKAWDSGAVIGTLVAFVVCMILFVIEQWWLGENAMVHSVMIKRRTIWVGSMFSFLINSAFLVTFYYLPIYFQSVQGVSASTSGVRTVPFILAVTFCVVIVGQIITKTGYAFPWMIVGAAITTIGSGMIYTFDTHSPAGKWIGYQILCGIGVGVSFQVPVMLIQATTKDADVPLATATLLFIQTLGGAFGVSSAQAAFQNTLLKQLAITAPGLNPQIVLDAGASELKRVIPEQFLQGVLEAYVSGFRECLIVGIAFGGAAFLAAFGFRFTNIKRTAAAEA
What is the function of this protein?
MFS-type efflux pump involved in the modulation susceptibility to various compounds including the xenobiotics 2,3,5-triiodobenzoic acid (TIBA) and 2-chloro-5-hydroxypyridine (CHP), CuCl(2) several fungicides (clotrimazole, fludioxonil, vinclozolin, and iprodione), potassium superoxide KO(2), and the singlet oxygen-generating compound hematoporphyrin.
What are the official names of this protein?
MFS-type transporter MFS54.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATP6_ENTFA
Sequence: MEEKKLLFNIGPIWFDGTIVLMVLLTCIIVFAFVYACTRNMKLRPKGKQTVIEWLVDFIRGIITDNLPRKEVSNFHLMAFTLFMFVLVSNILGLVTKIVVGDDLSVWKSPTADPIVTLTLAMMMIVLTHFFGMKRFGFKGYLVNSYLRPVGFLLPVKLMEEFTNLLTLGLRLYGNIFAGEVLLGLIAGTVASVGLWVIPLAIPLEMIWVAFSIFIGCIQAFIFVTLSMVYMSHKIETEE
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DNLJ_MAGMM
Sequence: MSASRAAELRKRLNHYAHSYHTLDTSLVSDAEYDRLFRELQSLEAADPTLISADSPTHRVGGAILEGFEKVRHRVAMLSLDNAFSAQDLVEFHRRVQEGLAESVVVEAVQHYQDEYGLSDLGALVGRPGALEGVARDVTQRLNQTLSFVEPLQPPDTKSLLSSGRKAADILRRLRLWAAEQPQRVEYVAEPKLDGLAFSLTYAEGVLVRAATRGDGQEGEDVTAHARTIQDVPLRLQGAGYPALLEVRGEVYMPLATFEKLNAEARERGEKTFANPRNAAAGSLRQLDPKITASRGLRMFCYGTGYVEGGTLADRYAEILAALKGWGLRVSPEAERVEGAQGCLAYTERLGEKRETLPYEIDGAVLKVDSQRLRERLGFVARAPRWAMAFKFPATEESTTVQAIDLQVGRTGVITPVARLEPVAVGGVTVTNATLHNFLELARKDVRVGDRVIVRRAGDVIPEVVRVIPRESHGALAVYKEPVACPVCGAPTEREGGETALRCSGGLTCRAQVKEGVKHFASRKAMNIEGLGDKLVALLMQAGLVERISDLYRLHEQRQVLVGLERLGGKSVANLLEAIEQSKAQSAARFLFGLGIRDVGVTLAGSLAAHFTSLDALMAATVEDLVGIEDVGEVVARRVVHFFAQAHHGAELAALRALGVAAAGEPWRVEPDGHGVAAAEQPLSGLSVVLTGTLAGLTREAAAVRLEGLGAKVVASVSGKTGCLVCGESAGSKLAKAQKAGVPVLDEAALEGLFRGEIPPEIQARMQG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: DBH_XYLFA
Sequence: MNKTELIDGVAAAANLSKVEAGRAIDAVVNEITEALKKGDSVTLVGFGTFQVRPRAERPGRNPKSGELIMIAASNNPSFKPGKALKDAVKCSAG
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
DNA-binding protein HU.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RAB4A_BOVIN
Sequence: MSQTAMSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKDLDTDREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRAQAPSAQECGC
What is the function of this protein?
Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state (By similarity).  Involved in protein transport.  Plays a role in vesicular traffic.  Mediates VEGFR2 endosomal trafficking to enhance VEGFR2 signaling (By similarity).  Acts as a regulator of platelet alpha-granule release during activation and aggregation of platelets (By similarity).
What are the official names of this protein?
Ras-related protein Rab-4A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Cytoplasm. Early endosome membrane; Peripheral membrane protein. Recycling endosome membrane; Peripheral membrane protein. Note=Generally associated with membranes. Cytoplasmic when phosphorylated by CDK1.
Protein: PAHX2_ORYSJ
Sequence: MLPAGSLTDKQLHFFDANGYLVLGSFSSAEEVKAMRDRMAVLIDGFDGAGDVFSTKDHRQVKNDFFFKSAENISFFFEEKAFGDDGCLKQAKELSINKVGHALHELDPVFKKFSFGENVSSLFSSLRYKRPAVIQSMYIFKQPGIGGEVVPHQDNTFLYTNPPSCTGLWLALEDATKTNGCLWAIPGSHKNGLKRRMIRDENDTHFDHPSPTYDLKEFVPLEVKSGDLVVIHGDLVHQSFENLSLVSRHALSLHVIDTEGCEWSKQNWLQRKIPPQPLYEN
What is the function of this protein?
Converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA.
What are the official names of this protein?
Phytanoyl-CoA dioxygenase 2, Phytanoyl-CoA 2-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the PhyH family.
Protein: Y1658_METSB
Sequence: MLTALVYVAAALAEIAGCFSFWAWLRLGKSSLWLIPGTASLLLFAWLLTLIDVSAAGRAYAAYGGVYVTVSLLWLWAMEGVWPDRWDLGGATLCLIGAAIIILAPRPA
What are the official names of this protein?
UPF0060 membrane protein Msil_1658.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1901_SULDN
Sequence: MSRAKGNVAEDRASLFLLENGYMIVDKNFYSRFGEIDIIAYKEEVWHFVEVKSALDYELAVQNITKSKLSKLIKTGDVYLKKNALHVDYMYDAIIVTPENIWHLENITL
What are the official names of this protein?
UPF0102 protein Suden_1901.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: BPHF_NOVAR
Sequence: MQTPVNSFKAALREGPVQLGFWLALAHPDIAEICAGQGYDWLLIDGEHGPQTLPGIVAQLRAVEATPPCSAIVRVPGHDSVTIKQVLDLGAQTLMVPMVETAEQAKAIVTASRYPPAGERGLGGARASRWGGYPAYVAEANAQVCIIAQIETATAVDNIEAIAAVDGIDALFLGPADLAATEGLLGASSFDALFKLTGEALARIVATGKPAGILSRDERLVQQFLDGGARFIANGIDSFTFAKGAGDGLRRWRERIAAQGGV
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of 4-hydroxy-2-oxovalerate to pyruvate and acetaldehyde.
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase, HOA.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family.
Protein: YQGF_NITWN
Sequence: MPASVLPLVEAAAHWPARGALVGLDLGTKTIGVAVSDPDRRLATGVETIRRKTFTADAARLLAIAGERRAEGFILGLPINMDGSEGPRAQSTRAFARNLARLTDFAIGLWDERLSTAAVERELIGLDMSRARRAKVIDEHAAIFILQGALDRLATQRRTSGPG
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EZRI_MOUSE
Sequence: MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLQYVDNKGFPTWLKLDKKVSAQEVRKENPVQFKFRAKFYPEDVAEELIQDITQKLFFLQVKDGILSDEIYCPPETAVLLGSYAVQAKFGDYNKEMHKSGYLSSERLIPQRVMDQHKLSRDQWEDRIQVWHAEHRGMLKDSAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMLREKEELMLRLQDYEQKTKRAEKELSEQIEKALQLEEERRRAQEEAERLEADRMAALRAKEELERQAQDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEPVNYHVQEGLQDEGAEPMGYSAELSSEGILDDRNEEKRITEAEKNERVQRQLLTLSNELSQARDENKRTHNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEAM
What is the function of this protein?
Probably involved in connections of major cytoskeletal structures to the plasma membrane.  In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole.  Along with PLEKHG6, required for normal macropinocytosis (By similarity).
What are the official names of this protein?
Ezrin, Cytovillin, Villin-2, p81.
What are the subcellular locations of this protein?
Apical cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection. Cell projection, microvillus membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Cell projection, microvillus. Note=Localization to the apical membrane of parietal cells depends on the interaction with PALS1. Microvillar peripheral membrane protein (cytoplasmic side). Localizes to cell extensions and peripheral processes of astrocytes (By similarity).
Protein: JETC_BACCQ
Sequence: MKKLRLINWHYYSDETILFGKQTVISGHTGAGKSTVIDALQVLFISDERKIKFNSAAYEEANRTLINYLRGKIGTEEKPFVREGYFTTYIVAEFYDEKAGESFVIGISIDVFKDDEKVKEYFIIPKSEINMISFFSTKDEKRYVEKQADFCKKIREQFPEAIIEKSSNQYQKALLQRFGGLHERFVKTFARALSFKPIDNMKDFVYKNILDEKELKIDVMRNIFQTHEELQRELEELKERKEELERIDNIYLECVKLEADISIQEYVLRGLEYLLIQEEKSMCKKSIEQREKELRKCESDQKKTAEQKEHARKKETEYEIKIKDSAEQKRQKQLQEQIAQAKKECGDLECTKNIYVHSLAREEKDVSSLLNYQGNEYFSLSKDEKHALEIGRDCLAFLSHNDGTGGNREEQTLNKLGESLKRISGRFYKSTAELEHRSAELKTEEKELLSDIENLKRRKRPYPMSVEKLKGLLEKHLEDQSKVWILCEELEIKNDKWRNALEGYLNTQRFDILVEPHMFATALSIYEKEKWNLGLEGVGLVDTEKEQTYLGKVEKGSLAEEIVGGNPIVQARIHHLLGRVIKADNEQELRKYKTAVTATCMSYQRLVARQIPRKVYETPYIGAHAIQKQLEIKEENLKEIQTELQIVGYYIKDFKKWIEILEDKQSDYKNYILNFSLNDSILEFNKNINKWKSELNTLDLSRLESLRQKLKEWNGKYNQFNGEEGRLFEQIGKVKEELQRVNAELWKKEKAATEILEKWKNWKFEYRIELLQEAEQRYEQAISTNKAYGAIKNKYENNKKENQNKYEEKRGFLESERKSYNEARTFQGIIQAKDNKQYEEALRKIANLDIPKFEQEIKETLQQAEEEFQSHFIYKMREAIQAARREFNQLNHALGRFKFRNDTYRFVIKPSEQYKKFYDVIMDERVQPEISLFDFGDEDRAEILKDLFGRLVVGEYGENEEFVDYRNYLDFDLSINNENGTRFMSNLLREQSGGETQTPFYIAILASFQHLYRNKNTIRLVVFDEAFNKMDEERIQISLRLIKQLDLQLIAAVPDEKMAHMAAEADTAIIINRIGHSCFTDILSYPREDEAIGLQEQDSFSLIE
What is the function of this protein?
Component of antiplasmid transformation system Wadjet type I, composed of JetA, JetB, JetC and JetD.  Expression of Wadjet type I in B. subtilis (strain BEST7003) reduces the transformation efficiency of plasmid pHCMC05 (PubMed:29371424).  May be an ATPase (Probable).
What are the official names of this protein?
Wadjet protein JetC, Probable ATPase JetC.