PharMolix/UniProtQA huggingface dataset:
Protein: GCS2_MYCUA
Sequence: MMPVSGWRAVSSAPASSSAGRTANRIDFARSPRPTVGVEWEFALVDAETRDLSNEATAVIAEIGENPRVHKELLRNTVEVVSGVCGSAGEAIEDLRTTLGPARRIVHARGMELFCEGTHPFAQWSTQKLTDAPRYAELIKRTQWWGRQMLIWGVHVHVGVSSANKVMPIISALLNYYPHLLALSASSPWWGGEDTGYASNRAMMFQQLPTAGLPFQFQTWSEFEGFVYDQKKTGIIDHINEIRWDIRPSPHLGTIELRICDGVSNLRELGALVALMHCLVVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILDAESNERLVTDDLDDVLTRLEPVARSLSCADELAAVAEIPRVGASYQRQRRVAEEHDGDLRAVVDALIAELDI
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: GTE12_ARATH
Sequence: MVAIPNIKIKFGPQGSVRTFQTLSDSSKKIEHVVTEDLSQSSEKSKKRGGPKELDEVQPKKKQRLDCDWSSQCLALLRFLMEHRGGWLFKEPVDPVKMEIPDYFNVIQKPMDLGTVKSKLLKNVYSNADEFAADVRLTFANAMHYNPLWNEVHTIAKEINEIFEVRWESLMKKKVLRLSWNEVREGYKRQPVERDCSRRSSTGTSASSGVGLTKPAKENSEKGSLSSKPVKVQSKKNTPAVTPKALATCKCGRIICICLKSCSSFGSDVCSLTDCQLKNISGAQASELDPQSNGSDTSKKERNGSLKSQLDKPSNSDLLGNELKTAFPALPPVPPEKALRAAILKAQYAGTIIKAKHRIVLGQNNKADLIRIQIEKEQMERAQREEKARIEAEMRAAKVAERMRAQDELKQKRESQRLEIAKMKKGFDFERNNHSKLKKKFVKVCGCFSLTKARLLLEELGLVLKNDYCPELEVIGSEKFDAMRMDDLEEGEIL
What are the official names of this protein?
Transcription factor GTE12, Bromodomain-containing protein GTE12, Protein GLOBAL TRANSCRIPTION FACTOR GROUP E12.
What are the subcellular locations of this protein?
Nucleus.
Protein: PTC_LISMC
Sequence: MNKKRDFIDTKDFSKEEILFMIEIGRKMKESIKNGHYPQLLKHKTLGMIFEQSSTRTRVSFETAMTQLGGHAQYLAPGQIQLGGHESVGDTAKVLSRLVDILMARVERHQTVVELANTAAIPVINGMSDYNHPTQELGDAITMFEHLPKGKKIEDCKIVFVGDATQVCASTMFMATKLGMDFVQFGPKGFQLREEHLKIAEENCKVSGGSYLITEDVDIALKDADFIYTDVWYGLYEAELSEEERMKTFYPKYQVNKELISKAAPHVKFMHCLPATRGEEVTDEVLDAPYSVVIDEAENRLTAMRALLVYFMNPYVREAGFAVAEKYDAELELLLRNGAGL
What is the function of this protein?
Catalyzes the phosphorolysis of N-carbamoylputrescine to form carbamoyl phosphate and putrescine.  Is involved in the degradation pathway of the polyamine agmatine.
What are the official names of this protein?
Putrescine carbamoyltransferase, PTC, PTCase, Putrescine transcarbamoylase, Putrescine transcarbamylase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. PTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_SYMTH
Sequence: MLKARKVHFIGVGGYGMSALAMVLKQRGTAVSGSDVAASARTQRLAEAGVEVHIGAHDAAHIEGADVVVYSTQVPEDNPELAAARARGLRVLHRSELLAEFLNGRSIAVAGTHGKTTTSSMVACLLEKAGLDPTILLGGDLEVIGGTGKAGRGDWVVAEADESDRSFLRYHPRVAVVTNVEPEHLEFWEGSFARIQEGFRQFLRQVQPGGLAALCADDPTLRSIGQELRNQPGVVHVVFYGTHPEAEWRAENIRPWEKGIVYDCVRDGRLLGEVRLPIPGRHNALNSLGALVAGDYAGLSFRQMQETLLSFGNARRRFEVWADVDGIRVVDDYAHHPTEIRATLAAAREQAGRRVVAVFQPQRYSRTHWLMDEFATAFQDADVLVLTRIYSPPGERPIPGVSAEALARRIQANTGRPVAVISDQEEILRFLLAEVRPGDTVITMGAGDIWKVARALAQALQSRAVTRTASSGSGRPAPGSGR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_MARSD
Sequence: MKTYIPKDEDINREWFVVDAENMVLGRLATQIANKLRGKDKAMFTPHVDTGDFVVVLNADKIKVTGNKMDQKTYYKHTNHPGGLKERTLKVMLEKKPEVVIETAVRGMLPKNRLGKQMIKKLKVYAGTEHPHTAQQPKVLEF
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: NFL_BOVIN
Sequence: MSSFSYEPYYSTSYKRRYVETPRVHISSVRSGYSTARSAYSSYSAPVSSSLSVRRSYSSSSGSLMPSLESLDLSQVAAISNDLKSIRTQEKAQLQDLNDRFASFIERVHELEQQNKVLEAELLVLRQKHSEPSRFRALYEQEIRDLRLAAEDATNEKQALQGEREGLEETLRNLQARYEEEVLSREDAEGRLMEARKGADEAALARAELEKRIDSLMDEIAFLKKVHEEEIAELQAQIQYAQISVEMDVSSKPDLSAALKDIRAQYEKLAAKNMQNAEEWFKSRFTVLTESAAKNTDAVRAAKDEVSESRRLLKAKTLEIEACRGMNEALEKQLQELEDKQNADISAMQDTINKLENELRTTKSEMARYLKEYQDLLNVKMALDIEIAAYRKLLEGEETRLSFTSVGSLTTGYTQSSQVFGRSAYGGLQTSSYLMSARSFPSYYTSHVQEEQIEVEETIEAAKAEEAKDEPPSEGEAEEEEKEKEEAEAEAEAEAEAEAEEEEGAQEEEAAKEDAEEAKEEEGGEGEEAEETKEAEEEEKKDEGAGEEQATKKKD
What is the function of this protein?
Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber.  May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks (By similarity).
What are the official names of this protein?
Neurofilament light polypeptide, NF-L, 68 kDa neurofilament protein, Micro glutamic acid-rich protein, Neurofilament triplet L protein.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cell projection, axon. Cytoplasm, cytoskeleton.
Protein: RLME_ECOUT
Sequence: MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQSDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRDELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGSFVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRKP
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAG_SULIA
Sequence: MKYDIKLRFEVEGIVEKTDVIGAIFGQTENLFGDEFDLRELQDKGRLGRIIVEIRTKGGKSEGEIIIPSNLDRIETALIAAMVESVDKVGPYNSKFELIEIEDIRAEKLKKIIERAKGILSSWSKEKSLDIKEVINEISSAVKVGEITEYGPERLPAGPDVDKDPNLIIVEGRADVINLLRYGYKNVIAVEGATSRIPETVVSLSKMKKTVIAFLDGDHGGDLILKELLSNNVKIDFVARAPVGREVEELTGKEIAKALSNMMPLTQYLKKIQEAEQAIAKNVIAKEEKPIQLEATQQLVQITLPQNVLEEIKKLPGTLEGVLYDNNWNLIEKVQVRDIIPKLEAYEDNKVAYIVFDGVITQRLLDLASQKNIKMIIGARIGGINKRPQNVDILTFTDIISS
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  Also part of the exosome, which is a complex involved in RNA degradation.  Acts as a poly(A)-binding protein that enhances the interaction between heteromeric, adenine-rich transcripts and the exosome.
What are the official names of this protein?
DNA primase DnaG.
What is the protein family that this protein belongs to?
Belongs to the archaeal DnaG primase family.
Protein: RS7_YERE8
Sequence: MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAEAIVYTALETLAQRSGKDFLEAFEVALDNVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWIVDAARKRGDKSMALRLANELSDAAENKGSAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: MTAD_DESDA
Sequence: MRPCQTLVHAALIVTQDKERRILENASMAVTDGIVADLGPRHEMITCWQPRHEADFGRCLLLPGLVNAHTHSAMTFLRGLADDMPLMDWLNKRIFPVEQKLTPEIVRLGSLMGYAEMLRTGTTACVDMYIFEKEAMAAADQAGLRCLGGEVVFAFPSAAFPGPEAALEETRALAQKYAGHPRLSIAVNPHSVYTTTPEILAACRDLARELALPLHMHLAETAEETQICLHAHGKRPVACCRSLELLDGPCTLAHVVDVTPDELDFLAQRGAVAVHNISSNMKLASGASPVPAMLERGMPVALGTDGAASNNRLNMFTEMGRAALLHKLTGMDPTLLPAQTVLDMATLGGAAAMHDNRLGSLAVGKAADCVALDLAAPNMQPLYNAVSHLVYAATGMENRMTMIAGEIVYEDGKFTRFDYDALCREMTSIRDFVRRQAGLA
What is the function of this protein?
Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively.  Is also able to deaminate adenosine.
What are the official names of this protein?
5-methylthioadenosine/S-adenosylhomocysteine deaminase, MTA/SAH deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
Protein: CH603_FRAAA
Sequence: MAKMIAFDEEARRGLERGMNRLADAVKVTLGPKGRNVVLANKFGLPTITNDGVSIAREIELENSYERIGAELVKEVAKKTNDVAGDGTTTATILAQALVREGLRNVAAGANPLGLKKGIEVAVERVSEELSKQAKEVETKEQIASTASISAGDSAIGGLIAEALDKVGKEGVVTVEESNTFGLELELTEGMRFDKGYISPYFVTDADRQEAVLDDPYILIVNSKIAAVKDLLPLLEKVMQTSKPLVIISEDVEGEALATLVVNKIRGTFKSVAVKAPGFGDRRKAILGDIAILTGGQVISEDVGLKLESTSLDLLGRARKIVVTKDETTVVEGSGDPDQIAGRVSQIRNEIDKSDSDYDREKLQERLAKLAGGVAVIKVGAATEVELKEKKHRIEDAVSNAKAAVEEGIVAGGGVALLQASITAFEKLDLSGDEATGANIVRLALEAPIKQIAFNSGLEGGVVVDKVRNLPTGHGLNAATGEYVDLIATGIIDPAKVTRSALQNAASIAGLFLTTEAVVANTPEYAEADAANVDAAMRSQGF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 3, 60 kDa chaperonin 3, Chaperonin-60 3, Cpn60 3.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHH2_GLOVI
Sequence: MVTIETRADQMVLNLGPHHPSTHGVLRLIVTLDGENVVDCRPVLGYLHRGMEKIGENRTIIQYLPYCSRWDYAAAMMNEAPVVNAPEAMAGVKVPRRASYIRVIMLELSRIANHLLWVGPFLLDMGAQSPFFYILRERELILDLFEAATGLRMVGNNYFRVGGVTVDLPYGWVDKAHDLCDVIPGKIDEYERLITNNPIFRRRIENLGYISREDAINWGLSGPMLRASGVKWDLRKVDHYEIYDELDWDIAWDTGGDCLARYIVRIKEMRESVKIIRQALDQLPGGPYEQLEARRLAEGPKSEWNSFDYQFIGKKSSPTFKIPTGEYYARSEEAKGELGIYVVGRDDTTPWRWKIRTPDFANLAILPMILQGTKVADLVVVLGSIDIIMGSVDR
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H 2, NAD(P)H dehydrogenase subunit H 2, NADH-plastoquinone oxidoreductase subunit H 2, NDH-1 subunit H 2, NDH-H 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: COAD_ACIBC
Sequence: MSKTRVIYPGTFDPITNGHVDLVTRASRMFDEVVVAIAIGHHKNPLFSLEERVALAQSSLGHLSNVEFVGFDGLLVNFFKEQKATAVLRGLRAVSDFEYEFQLANMNRQLDPHFEAVFLTPSEQYSFISSTLIREIARLKGDVTKFVPQAVVEAFERKHQQGW
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 024R_FRG3G
Sequence: MWQYLPILLMTMISQLEWTVAAVKRYPAGGFITGDKLSRVFEALPWRVAVVSDEPEKYEGFPILTEEDPAVFEDADCILFAVSDPKCVTGAMKSVFMASSKTAWVVYDGTETRATVRSWMRRLWRAETYVPLLTHRGFVTDVCVYSQPDSERYVSVMTATAHFYSNRLEVLEEMAFVPHLAYAKLAMGRYTVLDGCMSVKGSADVAPLNRSMWFLTAAAIPHGEIDTDSLFSDPGAVYSCGSALREALGSLPEGSTSVVAVRNSSYRKYVRGILGPNFRVETFTNVVKTWGVYDYVLLPMGISDSYKQGRDLMEKLEMPGGHRVVTFAPENYTVNEVHLNRPLKYAIKRMDLITPMVLRHVSLNK
What are the official names of this protein?
Uncharacterized protein 024R.
Protein: THIE_LIMF3
Sequence: MLFKNEILRCYLIGGSQDTHHDPDEFLTKVEAAMQAGITAFQYREKGTSTLSKAETLALGQQVRELATKYGVPLFVDDDLELAAAIKADGIHVGQKDQRIEEVLAAVSDQLMVGYSCNTAAQVAHANQLNVDYIGTGPVFPTISKDDAGSALGVDGLADFVEQSAHPVVAIGGISLDNVGATLTSGCAGLSMISMVLGADDVAGTVKKILELY
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: RL31_GEOSW
Sequence: MKPGIHPEYKKVIVRCACGNEFESGSVKDELRVEICSECHPFFTGRQKFVSAAGRVDKFNKKYGLK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: SFSA_SHEB9
Sequence: MEFTPPLQQGILLRRYKRFLADVQLSDGSEITLHCPNTGSMRNCLYPGETVWFSTSDNPKRKYAHTWELMTTPNAGLIGIHSGQANTLAEEAINKGIITELTGYDSLSREVKYGDENSRIDILLQGAQKPACYIEVKSCTLLEDGQGYFPDAVSLRGQKHLRELMHMVSQGHRAVLLFVVQHSEIFSVAPAAHIDPEYAKLLKIAVLAGVEVLAYRCEMSPTEIHLAQACDVRV
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: LPTE_YERPY
Sequence: MRHRILTLLLGLAVLVTAGCGFNLRGTTQVPTELQKLLLESSDPYGPLARSIRQQLRLNNVTIVDDAMRKDIPTLRIIGSSESQETVSIFRNGVAAENQLVLHVQAQVLIPGHDIYPLQVNVFRTFFDNPLTALAKEAEAEVLRQEMREQAAQQLVRQLLTVHAAEVKNTQKNGDKPVSDANAAQGSTPTAVNETTLGEPAVSTSAK
What is the function of this protein?
Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.  Required for the proper assembly of LptD.  Binds LPS and may serve as the LPS recognition site at the outer membrane.
What are the official names of this protein?
LPS-assembly lipoprotein LptE.
What is the protein family that this protein belongs to?
Belongs to the LptE lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: PYRC_ALISL
Sequence: MTTLTITRPDDWHLHLRDGDVLTDTVRDSGRYNGRALIMPNLVPPVITTEQALSYRERIQAVNSSNTFAPIMSLYLTEKTTSDEIRKAKATGYIVAAKLYPAGATTNSDSGVSDVQKVYPILKTMQEEGMLLLIHGEVTTHDIDIFDREKTFLDTVLAPIVNDFPELKIVLEHITTKDAADFVKNAGPNVAATITAHHLLFNRNHMLVGGIKPHFYCLPILKRNTHQLALIEAATSGSPKFFLGTDSAPHSKEKKEAACGCAGSYTAHASIELYTEVFENEGKLDNLEAFASFNGPDFYNLPRNTDTITLVKEAWITPETMSFGNDVVVPIRAGEAVEWLVK
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: RL5_HELMI
Sequence: MARLKEKIQTDVNAAMMQRFGYKNVMQIPRLEKVVVNMGLGEAIQNPKGLDAAVGDLTRITGQKPVITTAKKSIAGFKLREGMKIGCKVTLRGDKMYDFVDKLVNLSLPRVRDFRGVSPKSFDGRGNYTLGLKEQLIFPEIEYDKIDRLRGMDVTFVTTAKTDEEARELLRLIGMPFRAE
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: Y449_HAEIN
Sequence: MTMFKKISVLFFTLILAGCSSWSSVTNYIPFMGNDKKVIDLDKDKIDQKSYAAAYEATVATYKGRVNENFFVDNFASGANDWYLGRILVPVKQIQDKLYTGGHDSDVYAYYSGVLHAEALQANLKRLSANCWEKVDSQSMAQGIYDAMRDLQKGEARGENDEYIVQGSEALLKACTSK
What are the official names of this protein?
Uncharacterized protein HI_0449.
Protein: SGPL1_PONAB
Sequence: MPSTDLLTLKAFEPYLEILEVYSTKAKNYVNGHCTKYEPWQLIAWSVVWTLLIVWGYEFVFQPESLWSRFKKKCFKLTRKMPIIGRKIQDKLNKTKDDISKNMSFLKVDKEYVKALPSQGLSSSAVLEKLKEYSSMDAFWQEGRASGTVYSGEEKLTELLVKAYGDFAWSNPLHPDIFPGLRKIEAEIVRIACSLFNGGPDSCGCVTSGGTESILMACKAYRDLAFEKGIKTSEIVAPQSAHAAFNKAASYFGMKIVRVPLTKMMEVDVRAMRRAISRNTAMLVCSTPQFPHGVIDPVPEVAKLAVKYKIPLHVDACLGGFLTVFMEKAGYPLEHPFDFRVKGVTSISADTHKYGYAPKGSSLVLYSDKKYRNYQFFVDTDWQGGIYASPTIAGSRPGGISAACWAALMHFGENGYVEATKQIIKTARFLKSELENIKGIFVFGNPQLSVIALGSRDFDIYRLSNLMTAKGWNLNQLQFPPSIHFCITLLHARKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQTTVDRNMVAELSSVFLDSLYSTDTVTQGSQMNGSPKPH
What is the function of this protein?
Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine.  Elevates stress-induced ceramide production and apoptosis (By similarity).  Required for global lipid homeostasis in liver and cholesterol homeostasis in fibroblasts.  Involved in the regulation of pro-inflammatory response and neutrophil trafficking.  Modulates neuronal autophagy via phosphoethanolamine production which regulates accumulation of aggregate-prone proteins such as APP (By similarity).  Seems to play a role in establishing neuronal contact sites and axonal maintenance (By similarity).
What are the official names of this protein?
Sphingosine-1-phosphate lyase 1, S1PL, SP-lyase 1, SPL, SPL 1, Sphingosine-1-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family. Sphingosine-1-phosphate lyase subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type III membrane protein; Cytoplasmic side.
Protein: RL30_MYCA9
Sequence: MADVKITQVRSTIGARWKQRESLKTLGLRKIRQTVVREDNAQTRGLLQVVRHLVTVEDVK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: TAGE_BACSU
Sequence: MSLHAVSESNIKQIPDMDYYFISGGLPSNYGGLTKSLLLRSKLFGEECNQNTFFLTFRFDLELSSKIDELYSNGKIDKKFTSVINLFDDFLSVRTNGKRSYEERIGLDQIKKQVGMGKFAKTLLRLFGKKNNEMSVVYYGDGETIRYVDYWNDKNQLIKREEYTKNGNLVLVTHYDVQLNKMYLQEYINDQNQVYLDKLYVWNNEEKDVQLSHIIWYSLEGEIKVKDESELRQYWIEYLQKQNDKPKLFLVDSRPQDKHVFKVKKSPSSYYGAIIHNKHYGSNKYQIKGRYKEVFSQMYNLDAVFFITEEQLEDFKLISGEQETFFFTPHTIDKPLDPAVLNVPSEKYKAVIISRLASMKNLIHAVKAFSLVVKEIPEAKLDIFGSGEDFEKIKKEIEDTKLQNNVFLKGYTDNPDSEFQKAWLTISTSHFEGFGLSNMEALSNGCPVVTYDYDYGARSLVTDGANGYVIEQYNIEKLGQAIISLMKDESTHQKFSEQAFKMAEKYSRPNYIENWAFALNQMIEVRIEREKFSKKVGKKDPSISSYTEDFDKTKIEIDIENFDHNDIKKIRLVGLDRKNKAEIISTNLQNDQLFVIDLEKDVNIEKIAANKTQVIDFYIVFNANGHIKTMRRLSSEETKLSGNSIDTNNGYRVEPYTTVKGNFSWRVTEIKES
What is the function of this protein?
Catalyzes the addition of glucose to the C-2 hydroxy group of the glycerol units in teichoic acid.
What are the official names of this protein?
Poly(glycerol-phosphate) alpha-glucosyltransferase, Major teichoic acid biosynthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNCH_PROM5
Sequence: MNPHSWLILKRKVRFGDCDSAGVIHFHNLLRWAHESWEESIDIYGISHQVIFPSCHSHENQNILPIVNCEANFLLPIKLGDLLTVKIFPKKISNHLFQVNTLFLKDEIKVAEGKIIHCSLDMNSKLKVKLPDQLERWIEASNINTHLKEC
What is the function of this protein?
Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis.
What are the official names of this protein?
1,4-dihydroxy-2-naphthoyl-CoA hydrolase, DHNA-CoA hydrolase, DHNA-CoA thioesterase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. DHNA-CoA hydrolase subfamily.
Protein: GANB_BACLD
Sequence: MKNVLAVFVVLIFVLGAFGTSGPAEAARDSGTAKSGLYVEKVSGLRKDFIKGVDVSSIIALEESGVAFYNESGKKQDIFKTLKEAGVNYVRVRIWNDPYDANGNGYGGGNNDLEKAIQIGKRATANGMKLLADFHYSDFWADPAKQKAPKAWANLNFEDKKTALYQYTKQSLKAMKAAGIDIGMVQVGNETNGGLAGETDWAKMSQLFNAGSQAVRETDSNILVALHFTNPETSGRYAWIAETLHRHHVDYDVFASSYYPFWHGTLKNLTSVLTSVADTYGKKVMVAETSYTYTAEDGDGHGNTAPKNGQTLNNPVTVQGQANAVRDVIQAVSDVGEAGIGVFYWEPAWIPVGPAHRLEKNKALWETYGSGWATSYAAEYDPEDAGKWFGGSAVDNQALFDFKGRPLPSLHVFQYVDTGTPFKN
What is the function of this protein?
Involved in galactan degradation (PubMed:15312766).  Degrades arabinose-free galactan to galactooligosaccharides, producing galactotetraose as the main product along with galactotriose, galactobiose, and galactose (PubMed:15312766).  May hydrolyze the beta-1,4-galactan linkages of the galactan portion of arabinogalactan type I, a pectic plant polysaccharide from which most of the arabinose has been removed (By similarity).
What are the official names of this protein?
Endo-beta-1,4-galactanase, Galactanase, Arabinogalactan endo-beta-1,4-galactanase, BLGAL.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 53 family.
Protein: MOC2A_DROME
Sequence: MNADGPVVNVHVLFFAKSRELANTPRSTVEVPTEITATELLDHLVSKFGLTSIRDNLILAHNESYIDNLSDRILFKEGDELAIIPPLSGG
What is the function of this protein?
Acts as a sulfur carrier required for molybdopterin biosynthesis.  Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group.  In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3.  After interaction with Mocs2B, the sulfur is then transferred to precursor Z to form molybdopterin.
What are the official names of this protein?
Molybdopterin synthase sulfur carrier subunit, Molybdenum cofactor synthesis protein 2 small subunit, Molybdenum cofactor synthesis protein 2A, MOCS2A, Sulfur carrier protein MOCS2A.
What is the protein family that this protein belongs to?
Belongs to the MoaD family. MOCS2A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADEC_ECODH
Sequence: MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIAGVGAEYTDAPALQRIDARGATAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCDVNGASFTLEQMLAWRDHPQVTGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYITAGIENCHESYQLEEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVASWSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAEESARLAQSAPPYGNTIARQPVSASDFALQFTPGKRYRVIDVIHNELITHSHSSVYSENGFDRDDVSFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVVIGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAAARECGPLPDEPFIQMAFLSLPVIPALKLTSQGLFDGEKFAFTTLEVTE
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: RUTB_VARPS
Sequence: MSTPARNTTLTSNTPAGAPRLPGAPAPQVLPARPEPLALHASDSALIVVDMQNAYASMGGYVDSAGFDISGAQGTIANIARTIAAARTAGMLVVFLQNGWDAAYVEAGGPGSPNWHKSNALKTMRARPELAGKFLAKGGWDYELIAEMKPQPGDIVVPKTRYSGFFNSTLDSTLRARGIRHLVFTGIATNVCVESTLRDAFHLEYFAVMLEDATHELGGAAIQKASVYNVETFFGWVSTVDDFVRSFAPATA
What is the function of this protein?
Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate.  The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.
What are the official names of this protein?
Ureidoacrylate amidohydrolase RutB.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family. RutB subfamily.