PharMolix/UniProtQA huggingface dataset:
Protein: PSBD_DIOEL
Sequence: MTIAAGRFTKEENDLFDIMDDWLRRDRFVFVGWSGLLLFPCAYFALGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGLWTFVALHGAFGLIGFMLRQFELARSVQLRPYNAIAFSAPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSALGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SUCC_VIBVU
Sequence: MNLHEYQAKQLFAEFGLPVPEGYACDTPQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGVELHDTKEGVKEFAQKWLGKNLVTYQTDANGQPVTKILVEEASNIANELYLGAVVDRATRKVVFMASTEGGVEIEKVAEETPELIHKAAIDPLVGPQAYQGRELAFKLGLQGDQIKQFVKIFMGLGEMFTQYDLALLEINPLVITGEGNLLCLDGKINIDSNALYRQPKLREMHDPSQEDKREAHAAQWELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDDNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVSVPVVVRLEGTNADLGRKVLAESGLDIIAAESLTDAAQKVVAAAEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: CLPS_SHEON
Sequence: MGKTGNIEHVEERVESELMPPSMYKVILNNDDYTPMDFVIEVLQIFFRKNEQEATDIMLTIHHQGKGICGIFPFGIAETKVIQVNQFARQNQHPLLCSLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: PKRI1_DANRE
Sequence: MAVENKDARPGKALKKESQPLIIAKTPAEEQRLKLERLMRNPDKAAPIPEKPKEWNPRAPPEFVRDVMGSSAGAGSGEFHVYRHLRRREYQRQDFLERLSEKQKLDEEYKEKLIENQKAAEDRTAKRRKKREKLKQKKLMAKKAKMESQKEEDSEKSSSSSASEGEEKDDDAEVPSFIMGKR
What is the function of this protein?
Required for pre-mRNA splicing as component of the spliceosome (By similarity).  Binds double-stranded RNA (By similarity).
What are the official names of this protein?
PRKR-interacting protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the PRKRIP1 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus.
Protein: PARN_DANRE
Sequence: MEVTRQNFKEVLPEVCNAVQEADFISIDGEFTGISDGPSVSALTNGLDTPEERYTKLRKHSMNFLLFQFGVCTFRYDQNQSTYITKAFNFYIFPKPFSRTSPDIKFICQSSSIDFLASQGFDFNKVFRSGIPYLNQEEECQLREQYEERRGQMNGAGPVSYTPPSGTGVCNVPEDQREFIRSVEEKVEALLKNTDQTLDLEPCTGFQRKLIYQTLNSKYSKGLHVEALETEKKERFIQISKVDDEERRRREQQKQQREQEELNDAVGFSRVIRAISKSGKLVVGHNMLLDVMHTIHQFCGPLPEELDDFKEVAMTVFPRLLDTKLMASTQPFKEIIHNTSLAELHKQLRQKPFRPPTTECPEGLQSYDTSTEQLHEAGYDAFITGLCFISMANYLGSFLTPPKSHISARSKLLEPFYNKLFLMRVIDIPYLNMSGPDLQPKRDHVLYVTFPKEWKTSDLYQLFSAFGNIQVSWVDDTSAFVSLSQTEQVQIAMNTSRYAESYRIQTYAEYLQSRQKNTHSSRKWASDGWADTSYPSVAMTTASGYSHTDNWHQAVKRSISPSLDEQNHGADSSWTNYSVKKIKTEGSCTQTYADVAGSCDWPRLQADEGGASVSPVAEEAELDEFSANQSQGKRSRKHKKRKSDASETTPPALFDVPQVW
What is the function of this protein?
3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails.  Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs and is also used to silence certain maternal mRNAs translationally during oocyte maturation and early embryonic development (By similarity).
What are the official names of this protein?
Poly(A)-specific ribonuclease PARN, Polyadenylate-specific ribonuclease.
What is the protein family that this protein belongs to?
Belongs to the CAF1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y255_MYCPN
Sequence: MQRTLNVGVILCESFISNAQNPVNSYIKIYENVRMFEFAIKLLQESRINFQKILLYVLEEQIPLVEKVVAKYENCWVFRSKHNEVEDIYEAKGFIEDKYKIGLKSSKNQASSYYDNCCFVVLEACRPLTSKKVVKNVYEKAMIDGAAVAVLPFERQLVCGDNTKAVRQLKDKGNMNYWRQSSTWELQFPQAYTLNKLNQYHKNLFMKARNMLDLMNISAKNPLSIVDGSAYSFRVVTSLDFEILLGILRNG
What are the official names of this protein?
Uncharacterized protein MG116 homolog.
Protein: GLPK_ECOL6
Sequence: MTEKKYIVALDQGTTSSRAVVMDHDANIISVSQREFEQIYPKPGWVEHDPMEIWATQSSTLVEVLAKADISSDQIAAIGITNQRETTIVWEKETGKPIYNAIVWQCRRTAEICEHLKRDGMEEYIRNNTGLVIDPYFSGTKVKWILDHVEGSRERARRGELLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHSLDWDDKMLEVLDIPREMLPEVRRSSEVYGQTNIGGKGGTRIPISGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNTGEKAVKSENGLLTTIACGPTGEVNYALEGAVFMAGASIQWLRDEMKLINDAYDSEYFATKVQNTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNANHIIRATLESIAYQTRDVLEAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGLAVGFWQNLDELQEKAVIEREFRPGIETTERNYRYAGWKKAVKRAMAWEEHDE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: RNH3_STRP4
Sequence: MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVSIYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFVTPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAVSVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISLEEKAEGKYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFCAKLHFKNTEKAKKRLER
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_HAES1
Sequence: MSDKINLMNLTRQQMRAFFQELGEKPFRADQLVKWIYHFGEDNFDHMTNINKKLREKLKTVAEIKAPEIAVEQRSADGTIKWAMQVGDQQVETVYIPETDRATLCVSSQVGCALACTFCSTAQQGFNRNLTVSEIIGQVWRASKIIGNFGVTGVRPITNVVMMGMGEPLLNVANVVPAMEIMLDDFAYGLSKRRVTLSTSGVVPALDKLSEMIDVALAISLHAPNDELRNEIVPINKKYNIKMLMESVNRYLNVSNANHGKVTIEYVMLDHINDGTEHAHQLAEVLKNTPCKINLIPWNPFPDAPYAKSSNTRIDRFQKTLMEYGFTVILRKTRGDDIDAACGQLAGDVIDRTKRTAQKKRFGKEIGTHQIY
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBH_EMIHU
Sequence: MALRTRLGEILRPLNAEYGKVAPGWGTTPVMGVFMGLFLVFLVIILQIYNSSIILENVDVDWVTVN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: UREG_BACSB
Sequence: MEPIRIGIGGPVGAGKTMLVEKLTRAMHKELSIAVVTNDIYTKEDAQFLLKHGVLPADRVIGVETGGCPHTAIREDASMNFPAIDELKERHPDLELIFIESGGDNLAATFSPELVDFSIYIIDVAQGEKIPRKGGQGMIKSVLFIINKIDLAPYVGASLEVMERDTLAARGDKPYIFTNLKDEIGLAEVLEWIKTNALLYGLES
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_METTH
Sequence: MSKQPRKQRKYIYEAPLHARRKMMSANLSRELREEYGRRSLPLRKGDKVEILRGDFRGHEGKVEKVDLKRYRVYVEGATIQKVDGTTVYFPLHPSNLRIVDLNLDDEKRIKILERKG
What is the function of this protein?
Located at the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: SNP_PODSI
Sequence: GYKHQCRDRCYGTCGTSCKYGASRPSCACALHGGYCCVARPYHYPYPHPRPVPLPAPAPRPAPHYPVHHPKWPHWRPHYKA
What are the official names of this protein?
Tissue- and phase-specific nuclear protein, Specific nuclear protein, SNP.
What are the subcellular locations of this protein?
Nucleus.
Protein: SEPF_CLOTE
Sequence: MAGKVLNKVMGFLGLEDEYEYEEYYEDTDELENSNESAEFEPIIHSNKKQGKVVSIHSTSTPKVSIVKPKTYDEVVDICDDLKDGKIVIVNSIELDPKVGQRLVDFVSGATYSLNGTLEEIEKGIYILSPSNVEVDSELKNQLSSKGMFSWNR
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: RL36_TRIL1
Sequence: MKVRASVKKICDKCKIIKRKGVVRVICDTPKHSQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: DPO4_TREDE
Sequence: MATEKVFFHVDIDAFFASVEQLDNPEYMGKPVIVGGQSERGVVSTCSYEARKFGVHSAMPILQARKLCPSGIFLRGRMDRYHEKSKEVMSIFKDFTPEIKQISVDEAFLNMTGMEKIFGTPKNSALLLKKTIKEETGLTVSVGCAQNKYIAKIASGRSKPDGLFIVKAGEEIDFMKSLPLKDVWGVGGKTRERLIAAGLTSVPQIFNSSEHLLQSILGNASGSFLFQAVRGELYDVFSDDVKSHSISTERTFEHDLFSHAEIDDVMFYLASELMYRIFDEKVKGKTVSVKIRYNDFTTVSVQSTGAVVNDTQDLFERARELFYKKFDNKTPIRLLGLCIMNIESDIPEAQTELFYSEKNVKKRKIEETMYTLTKKEGKNILKPARLLKKDKDGLE
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYK_MESHJ
Sequence: MKIMSKLNDQQQFRRDKLKNLVKNGFNFPSSTFEHDNLVEINEKFSQKSKEFFLENQVKIAFAGRLIRQRGPFFIIFSQNLQFQAYISKEFQKKNEFIFANLDLGDIIEVSGYLFKTQTGQLSIKVNNFSLLTKSLHPLPDQYYGIENPDEKYRKRYLDLLVNSESAKTFRLRSKIISLIRTFFDSQGFLEVDTPVLQPVLGGASAKPFITYYNSLSQNFYLRIATELPLKKLLVAGFDRVYEIGKIFRNEGFDSTHNPEFTSIEFYQAYANLEKIMDQTENLFRFLFEKLNLDPANFDFSNKKINFLEKFARYDMIEITSKLMNFDLKSANFADLVEKAKKEGVKIEPFFKKGHLINKFFEKFVEPTLINPTFIIGHPIEISPLAKSNPNNPNFTLRAELFICGKEFANMFDELNDPIDQLSRFQAQIIEKNQGNQEASEIDNEFVQALEYGMPPAGGCGIGIDRLTMLLTKNESIREVILFPQLKPKKD
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WBDQ_ECO57
Sequence: MFLHSQDFATIVRSTPLISIDLIVENEFGEILLGKRINRPAQGYWFVPGGRVLKDEKLQTAFERLTEIELGIRLPLSVGKFYGIWQHFYEDNSMGGDFSTHYIVIAFLLKLQPNILKLPKSQHNAYCWLSRAKLINDDDVHYNCRAYFNNKTNDAIGLDNKDIICLMRQ
What is the function of this protein?
It could participate in the regulation of cell wall biosynthesis by influencing the concentration of GDP-mannose or GDP-glucose in the cell.  May be involved in the degradation of GDP-mannose and GDP-glucose, diverting the GDP to the synthesis of GDP-fucose as required (By similarity).
What are the official names of this protein?
GDP-mannose mannosyl hydrolase WbdQ/WbhG, GDPMH.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: ISPE_CERS4
Sequence: MTEAFARAKINLTLHVTGQRPDGYHLLDSLVVFADVGDRVRAEPAEALSLAITGPQAANLPVADDNLVLRAARTLGGQGARLTLEKHLPVASGIGGGSADAAAALVALARLWQVPLPEPAAVLKLGADVPVCLEGRAVRMAGVGEILTPLAAPLPEGWLVLANPGVSVPTPPVFKALARRDNPPMPDDLPGWPTVEALAAFLATQRNDLEPPAIALAPEIARTRAALAAQRGCLLARMSGSGATCFGLFAAEEAARAAAEAIGAEHPGWWVAPARMVG
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: AROB_RHOOB
Sequence: MTEPVRVQVQTANPYPVIIGRGLLGELVDELTGTRTVAIFHQPPLAETAEAVRAALAEKGIDAHRIEIPDAEDGKDLAVAGFCWEVLGRIGLTRSDAVVSLGGGAATDLAGFVAATWMRGVRVIHVPTTLLAMVDAAVGGKTGINTEAGKNLVGSFHEPSAVLIDLATLETVPRNEIVAGMAEVVKTGFIADPVILELIEKDPEAALDPTGTVLPELIRRSVEVKAKVVAADLRESDLREILNYGHTLGHAIERRERYRWRHGAAVAVGLVFAAELGRLAGRLDDATADRHRTILELVGLPTTYDADAFGQLVEGMQTDKKNRAGVLRFVVLDGLAKPGRLEGPDPSLLVAAYSAVAREGTPGTGGAVLL
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPB11_PLAF7
Sequence: MSVPTLSNKPETVDLLVLAPGEKKVTCTISDKGDCNIFVIKLEDHTIGNLIKIQLCQDPKVLFAAYRQPHPLQNAIEITIKPKGYAGVKLLSDNVNNILSQVATLKENFAKKIQKYKESNSYYEDY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  It is composed of mobile elements that move relative to each other.  RPB11 is part of the core element with the central large cleft (By similarity).
What are the official names of this protein?
Probable DNA-directed RNA polymerase II subunit RPB11, RNA polymerase II subunit B11, DNA-directed RNA polymerase II subunit J.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ENK21_HUMAN
Sequence: MHPSEMQRKAPPRRRRHRNRAPLTHKMNKMVTSEQMKLPSTKKAEPPTWAQLKKLTQLATKYLENTKVTQTPESMLLAALMIVSMVVSLPMPAGAAAANYTNWAYVPFPPLIRAVTWMDNPIEVYVNDSVWVHGPIDDRCPAKPEEEGMMINISIGYHYPPICLGRAPGCLMPAVQNWLVEVPTVSPISRFTYNMVSGMSLRPRVNYLQDFSYQRSLKFRPKGKPCPKEIPKESKNTEVLVWEECVANSVVILQNNEFGTIIDWAPRGQFYHNCSGQTQSCPSAQVSPAVDSDLTESLDKHKHKKLQSFYPWEWGEKGISTPRPKIISPVSGPEHPELWRLTVASHHIRIWSGNQTLETRDRKPFYTVDLNSSLTVPLQSCVKPPYMLVVGNIVIKPDSQTITCENCRLLTCIDSTFNWQHRILLVRAREGVWIPVSMDRPWEASPSIHILTEVLKGVLNRSKRFIFTLIAVIMGLIAVTAMAAVAGVALHSFVQSVNFVNDWQKNSTRLWNSQSSIDQKLANQINDLRQTVIWMGDRLMSLEHRFQLQCDWNTSDFCITPQIYNESEHHWDMVRRHLQGREDNLTLDISKLKEQIFEASKAHLNLVPGTEAIAGVADGLANLNPVTWVKTIGSTTIINLILILVCLFCLLLVCRCTQQLRRDSDHRERAMMTMVVLSKRKGGNVGKSKRDQIVTVSV
What is the function of this protein?
TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain.  The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane (By similarity).
What are the official names of this protein?
Endogenous retrovirus group K member 21 Env polyprotein, EnvK1 protein, Envelope polyprotein, HERV-K_12q14.1 provirus ancestral Env polyprotein.
What is the protein family that this protein belongs to?
Belongs to the beta type-B retroviral envelope protein family. HERV class-II K(HML-2) env subfamily.
What are the subcellular locations of this protein?
[Transmembrane protein]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Surface protein]: Cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the membrane, but localizes to the extracellular surface through its binding to TM. SUBCELLULAR LOCATION: [Endogenous retrovirus group K member 21 Env polyprotein]: Virion.
Protein: SDHD_RHILW
Sequence: MNTILPADPARDEVLAGRPTLWVNPSYRKRAIDTSDLPVSRDDVQIARLNWQRLAPLLAECFPELKDSDGEIRSELVELKELREALGYRTREFGNVFIKADSHLPVAGSIKARGGVYEVFLFAENLARQNGLLGDGEDIRKLAAEEARSFFSGYTVAVGSTGNLGLSVGIAARALGFKATVHMSSDAKAWKVERLRRLGVEVIQHEADYTSAVENARDIADADPTIYFVDDEQSRHLFLGYSAAASELAAQLDERGITIDEENPLFLYLPCGIGGAPGGVAFGAKAIFGDNVHAFFVEPVQSPCTLVHMMSGSQELVSVYDVGLTNKTEADGMAVARMSAFVAKVMREMLAGVYTAADDDLFKLLRMAWITQRQKLEPSAAAALLGPHFLVHHGEGRRFQAEQGIEEKMSRATHILWTTGGSFVPEEQFQNFLRQAEAVG
What are the official names of this protein?
Probable D-serine dehydratase, D-serine deaminase, DSD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family. DsdA subfamily.
Protein: RHG07_CANLF
Sequence: MCRRKPDIMILTQIEAKEACDWLRATGFPQYAQLYEDLLFPIDISSVKREHDFLDRDAIEALCRRLNTLNKCAVMKLEISPHRKRSEDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSSKLDPAPGAPAEAPLKTAASHESMLTELSERQEVASVLSLSSTGSLPVHAPHAGDAATPRTNSVISVCSSGHFVGNDDSFCSLPSPKELSSFSFSMKGQEKNAKSKTRSLLKRMESLKLRGSPHSKHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISALNGNRINVPAVRKRSVSNSTQTSSSSSQSETSSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVMEQNCKNRESYPEDTVFYIPEDHKPGTFPKALSNGSFPPSGNNSSVNWRTGSFHGPGHISLRRENSSDSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENEDIFPELDDILYHVKGMQRIVNQWSEKFSDEGDSDSALDSVSPCPSSPKQIHLDVDNDRATPSDLDSTGNSLNEPEEPSDIPERRDSGVGASLTRSNRHRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRNVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNESAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQCVPKDQRLQAMKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGRLRNDESADYQHFLQDCVDSLFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRSTIEVPAMPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPVVGVRVNVLLSRYLIEPCGSGKSKLTYMCRADLRGHMPEWYTKSFGHLCAAEVVKIRDSFSNQNTETKDTKSR
What is the function of this protein?
Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling.  This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation.  Also functions in vivo as an activator of the phospholipase PLCD1.  Active DLC1 increases cell migration velocity but reduces directionality (By similarity).  Required for growth factor-induced epithelial cell migration; in resting cells, interacts with TNS3 while PTEN interacts with the p85 regulatory subunit of the PI3K kinase complex but growth factor stimulation induces phosphorylation of TNS3 and PTEN, causing them to change their binding preference so that PTEN interacts with DLC1 and TNS3 interacts with p85 (By similarity).  The PTEN-DLC1 complex translocates to the posterior of migrating cells to activate RHOA while the TNS3-p85 complex translocates to the leading edge of migrating cells to promote RAC1 activation (By similarity).
What are the official names of this protein?
Rho GTPase-activating protein 7, Deleted in liver cancer 1 protein homolog, DLC-1, Rho-type GTPase-activating protein 7, START domain-containing protein 12, StARD12, StAR-related lipid transfer protein 12.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, focal adhesion. Membrane; Peripheral membrane protein. Note=Colocalizes with EF1A1 at actin-rich regions in the cell periphery.
Protein: CYPH_MAIZE
Sequence: MANPRVFFDMTVGGAPAGRIVMELYANEVPKTAENFRALCTGEKGVGKSGKPLHYKGSTFHRVIPEFMCQGGDFTRGNGTGGESIYGEKFPDEKFVRKQPAPGVLSMANAGPNTNGSQFFICTVATPWLDGKHVVFGQVVEGMDVVKAIEKVGTRNGSTSKVVKVADCGQLS
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase, PPIase, Cyclophilin, Cyclosporin A-binding protein, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLB_CERRH
Sequence: SLQPASKSALASSWKTLAKDAATIQNNGATLFSLLFKQFPDTRNYFTHFGNMSDAEMKTTGVGKAHSMAVFAGIGSMIDSMDDADCMNGLALKLSRNHIQRKIGASRFGEMRQVFPNFLDEALGGGASGDVKGAWDALLAYLQDNKQAQAL
What are the official names of this protein?
Globin, Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: IRP1_AGRIP
Sequence: MKSFMVFVLIFACFSCYYAQESTNFYCGRTLSRALAVLCYGAESKRDAGWWIPQHGHHALAGVRGKRGPVDECCEKACSIQELMTYC
What are the official names of this protein?
Insulin-related peptide 1, IRP-1.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: POTC_ECO57
Sequence: MIGRLLRGGFMTAIYAYLYIPIIILIVNSFNSSRFGINWQGFTTKWYSLLMNNDSLLQAAQHSLTMAVFSATFATLIGSLTAVALYRYRFRGKPFVSGMLFVVMMSPDIVMAISLLVLFMLLGIQLGFWSLLFSHITFCLPFVVVTVYSRLKGFDVRMLEAAKDLGASEFTILRKIILPLAMPAVAAGWVLSFTLSMDDVVVSSFVTGPSYEILPLKIYSMVKVGVSPEVNALATILLVLSLVMVIASQLIARDKTKGNTGDVK
What is the function of this protein?
Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine.
What are the official names of this protein?
Spermidine/putrescine transport system permease protein PotC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.