PharMolix/UniProtQA huggingface dataset:
Protein: SYT_PYRAR
Sequence: MRVLYIHAERFSWDPRDPALDIRDEPVSGSASNALVVFVSVERGDSPDEGFLKAVAADVVETAKKVGASSIVVYPYAHLSTDLARPYTAREVVGKLYEVVKAQFKGQVLKAPFGYYKAFELKCLGHPLSELSRVFKPEEAKTEKRAEERRDYYVVLTPDGAEYDPAKFNYAGLDDFKALVEKEVFKRELGGGEPKYLDYLRKFGFEWEPMSDVGHMRYAPEATVMMELVEDYAYMVAKSLGIPVFKIRGTNMFKLSEYAIESHARLFGERLYVVESDTDLILRYAACFQQFAMVKDWVISYRHLPFGLLEIADSYRHEQPGETVLLFRLRRFYMPDLHIFTKDLKEAMEVTFKLHEVIFREIGKLGRTYVSLYNVTEDFYKGHREYLVELARREGKPILVRILPGQKYYWVLNVEFHIVDELGRPREIATFQIDVGNAQRFGIKYVDENNQVRYPVIIHTAILGSVERYLYAVFDTMAKMEKEGKTPRLPTWLSPVQTRVIPVSKENLKYAMAVADLLEAEGIRVDVDDREETLSKKIRDAETAWVPYIIVVGSKEEAEGTVTVRERGGGQYKAKAEELAKKIREEVKGYPQRPLYLPRLLSQRPSRH
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RM02_PARTE
Sequence: MYELKKSKKSKARFFSTTSTYFSYRKHQLFKFYIPKNPSRNNTGKVSMRCKRKKFKNLDLAINYARIEMGRNCLITKLSFWKEKKPYVALVRDSYNSLSYYIAPAGFFVGRTLKTLPTKHDYYKKGGWKFYIRGLGTYVMLRVLRVNDVIFNLLSPSRVLYRLALAAGTYFKILYQSFCKTFYVMTIPSGLIIRVPSEGLAVMGRNSNTQNNKRVLGLAGVNFFNGTNPRVRGVAMNPVDHPNGGRTKTPKPERSPGVE
What are the official names of this protein?
60S ribosomal protein L2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: COBS_THIDA
Sequence: MRGLILALGFLTRLPLPVLRDFQCAELVRAVVWFPAAGLVVGAAVALAAALGTVLDPWLGALAGVVMWAWITGGLHLDGLADTADALGAAHRDPARFLTVLADPHVGSFGVIVLVLQLAAKLVLLHWLLTLDLPWPALVLIPAWTRWAAAGWTLLLPPLKPGLGERFAWQGNRAGWGAGGLALAAVSAITPIAFVALIPAVLWGVWMWLKLGGQTGDILGAGIEWSESAALLLAGVSLALARGIIAG
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYR_MYCTO
Sequence: MTPADLAELLKATAAAVLAERGLDASALPQMVTVERPRIPEHGDYASNLAMQLAKKVGTNPRELAGWLAEALTKVDGIASAEVAGPGFINMRLETAAQAKVVTSVIDAGHSYGHSLLLAGRKVNLEFVSANPTGPIHIGGTRWAAVGDALGRLLTTQGADVVREYYFNDHGAQIDRFANSLIAAAKGEPTPQDGYAGSYITNIAEQVLQKAPDALSLPDAELRETFRAIGVDLMFDHIKQSLHEFGTDFDVYTHEDSMHTGGRVENAIARLRETGNIYEKDGATWLRTSAFGDDKDRVVIKSDGKPAYIAGDLAYYLDKRQRGFDLCIYMLGADHHGYIARLKAAAAAFGDDPATVEVLIGQMVNLVRDGQPVRMSKRAGTVLTLDDLVEAIGVDAARYSLIRSSVDTAIDIDLALWSSASNENPVYYVQYAHARLSALARNAAELALIPDTNHLELLNHDKEGTLLRTLGEFPRVLETAASLREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEQPTDLHTARLALCQATRQVIANGLAIIGVTAPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_HALS3
Sequence: MSEQDEVPSEDRRKYEFRKVIEELKDYEGSGTQLVTIYIPPDKQISDVVAHVTQEHSEASNIKSKQTRTNVQDALTSIKDRLRYYDTFPPDNGMVVFSGAVDSGGGRTDMVTEVLESPPQPIESFRYHCDSAFLTEPLAEMLGDKGLYGLIVLDRRESNVGWLKGKRVQPVKSAESLVPGKQRKGGQSAQRFARLRLEAIDNFYQEVAGMADDLFVPKRHEIDGILVGGPSPTKDEFLDGDYLHHELQDKVLGKFDVSYTDESGLSDLVDAGQAALAEADLMDDKSDMEEFFEELNGGKLATYGFEQTRRNLIMGSVDRLLVSEDLREDVVIYECPNDHEEYETIDRRNTSPEHTCSDCGEEATEVDREDAIDHLMSIADQRGTETHFISTDFEKGEQLLTAFGGYAGILRYSTGV
What is the function of this protein?
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
What are the official names of this protein?
Peptide chain release factor subunit 1, Translation termination factor aRF1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HXT12_YEAST
Sequence: MGLIVSIFNIGCAIGGIVLSKVGDIYGRRIGLITVTAIYVVGILIQITSINKWYQYFIGRIISGIGVGGIAVLSPMLISEVAPKHIRGTLVQLYQLMGTMGIFLGYCTNYGTKNYHNATQWRVGLGLCFAWATFMVSGMMFVPESPRYLIEVGKDEEAKHSLSKSNKVSVDDPALLAEYDTIKAGIEIEKLAGNASWSELLSTKTKVFQRVLMGVIIQSLQQLTGDNYFFYYGTTIFKSVGLKDSFQTSIIIGVVNFFSSFIAVYTIERFGRRTCLLWGAASMLCCFAVFASVGVTKLWPQGSSHQDITSQGAGNCMIVFTMFFIFSFATTWAGGCFVIVSETFPLRAKSRGMAIATAANWMWGFLISFFTPFITGAINFYYGYVFLGCLVFAYFYVFFFVPETKGLTLEEVNTMWLEGVPAWKSASWVPPERRTADYDADAIDHDNRPIYKRFFSS
What is the function of this protein?
Probable glucose transporter.
What are the official names of this protein?
Putative hexose transporter 12.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: EA59_LAMBD
Sequence: MLEFSVIERGGYIPAVEKNKAFLRADGWNDYSFVTMFYLTVFDEHGEKCDIGNVKIGFVGQKEEVSTYSLIDKKFSQLPEMFFSLGESIDYYVNLSKLSDGFKHNLLKAIQDLVVWPNRLADIENESVLNTSLLRGVTLSEIHGQFARVLNGLPELSDFHFSFNRKSAPGFSDLTIPFEVTVNSMPSTNIHAFIGRNGCGKTTILNGMIGAITNPENNEYFFSENNRLIESRIPKGYFRSLVSVSFSAFDPFTPPKEQPDPAKGTQYFYIGLKNAASNSLKSLGDLRLEFISAFIGCMRVDRKRQLWLEAIKKLSSDENFSNMELISLISKYEELRRNEPQIQVDDDKFTKLFYDNIQKYLLRMSSGHAIVLFTITRLVDVVGEKSLVLFDEPEVHLHPPLLSAFLRTLSDLLDARNGVAIIATHSPVVLQEVPKSCMWKVLRSREAINIIRPDIETFGENLGVLTREVFLLEVTNSGYHHLLSQSVDSELSYETILKNYNGQIGLEGRTVLKAMIMNRDEGKVQ
What are the official names of this protein?
Protein ea59.
Protein: SSPH1_BACCR
Sequence: MDVKRVKQILSSSSRIDVTYEGVPVWIESCDEQKGSAQVYDVSNPGESVHVDVTALEEK
What are the official names of this protein?
Small, acid-soluble spore protein H 1, SASP H 1.
What is the protein family that this protein belongs to?
Belongs to the SspH family.
What are the subcellular locations of this protein?
Spore core.
Protein: MUKF_GLAP5
Sequence: MQHELAQTIPELILWTKEREFSLSLSSDRLAFLLAIALYNNERTDGELLESDLQDIFRHVSNAFEQSEATQTQRANNAINDLVKQRFLNRFSSEFTEGLAIYRLTPLGVGVSEYYIRQREFSTLRLSIQLSIVADEIQRASNAAEEGGDERFWRNQVFAPLKFSVAEIFDSIDLSQRMMDENQQQIRERIAMLLSQNWHEAIATCQQLLDETSGNLRELQDVLNASGDKLQSQLLRIQSCLIGRDDLDFVDQLIVNLQNKLDRIISWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRVFGQRLRQSIQDYFESPWQLYIAKAEPLLDLRDDETELNEAEAVGELPTELEYESLTQVQEQIIATMQAHLAPFREQGKPIDLGAILREQLAMYPLSRHFDVARIIVDQAVKLGMASQDSQAIYPEWQSINDNGAEVQANVIDQYNK
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Not required for mini-F plasmid partitioning.  Probably acts via its interaction with MukB and MukE.  Overexpression results in anucleate cells.  It has a calcium binding activity.
What are the official names of this protein?
Chromosome partition protein MukF.
What is the protein family that this protein belongs to?
Belongs to the MukF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: RBL2_RHOPA
Sequence: MDQSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFAAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKMEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFAKDHREFARAFESFPQDADKLYPNWRAKLKPQAA
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase, RuBisCO.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type II subfamily.
Protein: CISY_KAJAU
Sequence: MSFLTVSRLAPKLLNSKNATYFLVAARNASASSTNLKDVLADLIPKEQTRIKNFKQQYGKTNIGQITVDMVYGGMRGMKGLVYETSVLDPEEGIRFRGYSIPECQKLLPKAPGGEEPLPEGLFWLLVTGQVPTEEQVNWVSKEWAKRAALPSHVVTMLDNFPTNLHPMSQFSAAITALNSESSFARAYSEGVHKSKYWEFIYEDSMDLIAKLPCIAAKIYRNLYREGSSIGAIDSNLDWSHNFTNMLGYSEPQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFSAAMNGLAGPLHGLANQEVLVWLTALQKELGGEVSDERMRDYIWNTLKSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPNDPMFKLVAQLYKIVPNVLLEQGRAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLVWSRALGFPLERPKSMSSDGLMTLVGAKSG
What are the official names of this protein?
Citrate synthase, mitochondrial, Citrate (Si)-synthase.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: KAD_PSEFS
Sequence: MRVILLGAPGAGKGTQAKFITEKFGIPQISTGDMLRAAVKAGTELGLIAKSVMDSGGLVSDDLIINLVKERISQEDCKNGFLFDGFPRTIPQAEALVKAGVELDAVVEIAVEDEEIVQRIAGRRVHEASGRVYHTVYNPPKVEGKDDVTGDDLVQRKDDTEETVRHRLSVYHSQTKPLVDFYQKLSAAQGKPKYSHIPGVGSVEAITAKVLQALS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_MYXXD
Sequence: MKVILREDIENLGKSGELVTVKDGFGRNFLLPRKKAVLASEQNLRQLEHEKAVIAARNAKLKGAAEEQAKKIGAIKVSIKRRVGDQDKLFGSVTALDIAEAVAAEGQSIDRRHIHLPEPIKALGNYEVELRLHRDVIAKIKLEVLPE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: EFTS_PARPJ
Sequence: MAAITASMVAELRAKTDAPMMECKKALTEADGDMARAEELLRVKLGNKASKAASRVTAEGVVASFIGGNAGSLVELNCETDFVSKNDDFLGFSKKVAELVATQNPADVAALAALPLDGSTVDAVRLALVGKIGENLSIRRFVRFETSNKLAAYLHGTRIGVLVEYTGADEQVGKDVAMHIAAMKPVSLSSDDVPADLIAKERSIAEQKAAESGKPAEIVAKMVEGSVQKYLKEVSLLNQTFVKNDKQTIEQMLKAGNSSVQKFALFVVGEGIEKKQDDFAAEVAAQVAAAKQQ
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_CHLCH
Sequence: MKIHLDRTSSGFCIGVQGTINVAEDKLQELGQLYSYGDVVHNEVEVKRLEALGLVTVDDAGFKQLSNTSVLIRAHGEPPATYTIAAENNLAITDTTCPVVSRLQRTTRLLFQLGYQIIIYGKRVHPEVIGLNGQCDNCALIIKHADLSDPKELEGFEPSAKTALISQTTMDIPGFYELKANLEAYVARVNGSAVEPWMAIRDIDITADMSKVRTMPRYVFKDTICRQVSSRNQKLHDFSLANDVVVFVAGKKSSNGQVLFNICKAANPRTFFIEDIEEINPEWFAAHEGKAVESVGICGATSTPMWHLEKVANYIEATYANSESIIAQ
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: LEC1_EUCSE
Sequence: GRYTVQNQWGGSSAPWNDAGLWILGSRGNQNVMAVDVNSSDGGANLNGTMTYSGEGPIGFKGARRGESNVYDVENQWGGSSAPWHAGGQFVIGSRSGQGVLAVNITSSDGGKTLTGTMTYEREGPIGFKGTQSGGDTYNVENQWGGSSAPWNKAGIWALGDRSGQAMIAMDVSSSDGGKTLEGTMQYKGEGPIGFRGKLSGANNYSVENQWGGSSAPWNAAGDWLIGDRHNQNITAVKVSSDNDGKNLDGTCTYEREGPIGFKGVATS
What is the function of this protein?
Lectin specific for high mannose N-glycans, recognizes the branched moiety of these glycans.  Does not recognize other types of N-glycans or monosaccharides.  Agglutinates trypsin-treated sheep and rabbit erythrocytes and untreated sheep erythrocytes.  Has mitogenic activity on mouse lymphocytes.  Does not require metal ions for activity.
What are the official names of this protein?
Lectin ESA-2.
What is the protein family that this protein belongs to?
Belongs to the bacterial lectin family.
Protein: KBL_BOVIN
Sequence: MWAGRVLHAALSRAPRESRAQSALAQLRGILEEELESIRGAGTWKSERVITSRQGPHIHVDGAPGGIINFCANNYLGLSSHPEVIQAGLRTLKEFGAGLSSVRFICGTQSIHKDLEAKIARFHQREDAILYPSCFDANTGLFEALLTSEDAVLSDELNHASIIDGIRLCKAHKYRYRHLDMADLEAKLQEAQKHRLRLVATDGAFSMDGDIAPLQEICRLASQYGALVFVDESHATGFLGATGRGTDELLGVMDQVTIINSTLGKALGGASGGYTTGPGALVSLLRQRARPYLFSNSLPPAAVGCASKALDLLMESNAIVQSMAAKTLRFRSQMEAAGFTISGANHPICPVMLGDARLALNIADDMLKRGIFVIGFSYPVVPKGKARIRVQISAVHSEEDIDRCVEAFVEVGRLHGALP
What is the function of this protein?
Pyridoxal phosphate (PLP) dependent enzyme, which catalyzes the cleavage of 2-amino-3-oxobutanoate to glycine and acetyl-CoA.  Catalyzes the second reaction step on the main metabolic degradation pathway for L-threonine.
What are the official names of this protein?
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial, AKB ligase, Aminoacetone synthase, Glycine acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion. Nucleus. Note=Translocates to the nucleus upon cold and osmotic stress.
Protein: CPLX2_BOVIN
Sequence: MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTVLKYLPGPLQDMFKK
What is the function of this protein?
Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons.  Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles.  Also involved in mast cell exocytosis.
What are the official names of this protein?
Complexin-2, Complexin II, CPX II, Synaphin-1.
What is the protein family that this protein belongs to?
Belongs to the complexin/synaphin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Presynapse. Nucleus. Perikaryon. Note=Translocated from the perikaryon to the presynaptic terminals during maturation of neuronal cells. In mast cells, cytosol and nucleus. Becomes enriched near plasma membrane following stimulation.
Protein: RL25_BACTN
Sequence: MKSIEVKGTARTIAERSSEQARALKEIRKNGGVPCVLYGAGEVVHFTVTNEGLRNLVYTPHIYVVDLDIDGKKVNAILKDIQFHPVKDNILHVDFYQIDEAKPIVMEVPVQLEGLAEGVKAGGKLALQMRKIKVKALYNVIPEKLTVNVSHLGLGKTVKVGELSFEGLELISAKEAVVCAVKLTRAARGAAAAAGK
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: RIBB_ARCFU
Sequence: MILDFEESLRAFRKGSPVLIYDFEDREGETDIAIPAIHVGKDEVAMMRIDGGGLICVAIHPVAAEKLGLPFMHDVLRIASEKLPEIRKVADADDIKYDSRSSFSLWVNHRDTFTGITDVDRALTIRRIGEVVDEVMMGKKVDFGREFRSPGHVALLRAADKLTYERVGQTELSVALAEMAGIAPAVAICEMLDAETGKALTKEKAMEYAEEKGIPFIDGRTIVEHYRKFREVEVSLFV
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: EVS_ACTMD
Sequence: MDSPAGYRIHDNIPLPGNLDQVDVHVTRDDDYRIHVLPDVDRAVDALLTELDGRRAVVITDDVVADLHEGRVSAELAARGQLIGRTAIRAGEKSKSLTTAFELIDWLAEVNLARRDVVIALGGGVVVDTVGFVASAYMRGVPYVNMPTTLLAQVDAGIGGKVAVDHSEAKNLVGAFYQPKAVISCLEHLRTLDTRQIRSGLAEVVKKAVIASPELFDYIEANADDLLACASPAIDVLVHAAGAIKTKLVGRDPYEIDLRRPLNFGHTTGHAVETVTNYGPVLHGEAVAFGMVVAVDVARARGLVVPEVADRVTALIRRLGLPVALEELGAVPRVDDVVAALLKIRQIRDGSLRFVLPVELGATVIAEDVTEEEVRAALVRLR
What is the function of this protein?
Catalyzes the conversion of sedoheptulose 7-phosphate to 2-epi-valiolone, which may serve as an alternative precursor for aminocyclitol biosynthesis.
What are the official names of this protein?
2-epi-valiolone synthase, EVS, Sedoheptulose 7-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. EVS family.
Protein: GATA_PELUB
Sequence: MSDITSLTLTELVKNIKDKKISSEETTKAFIDRGEKSRDLNTYITEDFSNALLKAKSFDQKPNFDLKLPGVPIAVKDLFCTKDVKTTAGSKILNNFIPPYESTVTQNIWNEGAILLGKLNCDEFAMGSSNETSFFGNVQSPIDKGLVPGGSSGGSASALAANLTPITIGTDTGGSIRQPASFTGTVGLKPTYGSCSRYGIVAFASSLDQAGPMSKDVKDCALLQEIISTYDEKDSTSIDFKRNEYSKELTNNIKGKKIGIPKEYRVDGMPKEIEDLWTKGIEYAKDCGAEIVEISLPHTNYALPTYYIVAPAEASSNLARYDGVKYGFRSKGENLIDMYEKTRSEGFGSEVQRRIMIGTYVLSSGYYDAYYLKAQKVRKLIKNDFDEAYKKVDAILTPSTPSAAFKIGEKTNDPVSMYLNDIFTVPVNLAGLPAISIPAGIDVKGYPLGLQIIGKAFDEQNILNIAYAMEEKIQFKNKITDWWIK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: PVK3_EUBPO
Sequence: GSSGMIPFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-3, EubPo-PVK-3.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: BOPE_BURM9
Sequence: MTYNPRIGGFTHVKQASFDVHVKRGEAQPRTSFAQQIKRIFSKIGETLGQLFRHRAPDSAPGRVRLQGVRYVGSYRPTGDAKQAIRHFVDEAVKQVAHTRTPEIRQDAEFGRQVYEATLCAIFSEAKDRFCMDPATRAGNVRPAFIEALGDAARATGLPGADKQGVFTPSGAGTNPLYTEIRLRADTLMGAELAARPEYRELQPYARQQAIDLVANALPAERSNTLVEFRQTVQTLEATYRRAAQDASRDEKGATNAADGA
What is the function of this protein?
Activator for both CDC42 and RAC1 by directly interacting with these Rho GTPases and acting as a guanine nucleotide exchange factor (GEF).  This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, thus promoting bacterial entry into non-phagocytic cells (By similarity).
What are the official names of this protein?
Guanine nucleotide exchange factor BopE, Effector protein BopE.
What is the protein family that this protein belongs to?
Belongs to the GEF (guanine exchange factor) SopE family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the bsa type III secretion system.
Protein: SLAM_MORCA
Sequence: MTITPVYTTFTPTKTPIKFFMAGLTFLIAHISHADDGRTDNQEPINQEIATLEPIINHAQPELLSHDALTPKIEPILAQTPNPAEDTLIADEALLLDNPDLLNHALNSAVMTNHMAGVHALLPIYQKLPKDHQNGILLGYANALAALDKGNAKKAIDELRRIIAIMPEYNVVRFHLARALFMDKQNEAALDQFNKLHADNLPEEVRQVVGQYRQALKQRDSWTWQVGMNLAKEDNINQTPKNTTQGQWTFDKPIDAITLSYQLGADKKWSLPKGAYVGANAQIYGKHHQNHKKYNDHWGRLGANLGFADAKKDLSIETYGEKRFYGHERYTDTIGIRMSVDYRINPKFQSLNAIDISRLTNHRTPRADSNNTLYSTSLIYYPNATRYYLLGADFYDEKVPQDPSDSYQRRGIRTAWGQEWAGGLSSRAQISINKRHYQGANLTSGGQIRHDKQMQASLSLWHRDIHKWGITPRLTISTNINKSNDIKANYHKNQMFVEFSRIF
What is the function of this protein?
Required for correct export to the cell surface of some cell outer membrane lipoproteins (tested with TpbP) upon heterologous expression in E. coli and probably also in Moraxella.
What are the official names of this protein?
Surface lipoprotein assembly modifier, Slam.
What is the protein family that this protein belongs to?
Belongs to the Slam family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: TCPI_CLAP2
Sequence: MMSKRCLKRNQTLIPELLKNHGALLYGDTSVVDLSTAENQLLMEELLPEFQAAFDANTWSSQELAYSEGVGGCPKVRGLIADLVNSHFQPHAQVDKSHIVLGAGGCFALNALIEAICDPGDGILIAAPYWPGLDLSISVHNDAKAVVVRVPHEDFFRVESIRHYSKALLSAPNLVKAMIICNPHNPLGRNYPRETLQAIVDFCAERQIHLISDEVYALSQHVQPTSENPSAGFVSALSLDASHARGLVHVVYSLSKDFGCNGIRLGAFISQDNKAVVMSGALSTHCQTSTMATLVAQKIILTDENIQFVNTYGRGLLKSAYTVMEEFLNQHRIEFVSAECGMYIFAKLCGDRTSVDDEWLFQAILRRNGLVLSAGTDYHCKTPGWFRICYGCDREKLRHGLDRLRDCLQEFGETEFKFPFNDACF
What is the function of this protein?
Probable aminotransferase; part of the gene cluster that mediates the biosynthesis of an unusual class of epipolythiodioxopiperazines (ETPs) lacking the reactive thiol group important for toxicity (PubMed:27390873).  Firstly, L-tyrosine is prenylated by tcpD, before undergoing condensation with L-glycine in a reaction catalyzed by the NRPS tcpP leading to the diketopiperazine (DKP) backbone (PubMed:27390873).  Afterwards the alpha-carbon of tyrosine is oxidized by the cytochrome P450 tcpC to form a hydroxyl group (PubMed:27390873).  However, in contrast other ETP biosynthesis pathways studied so far, tcpC is not able to bishydroxylate the DKP at both alpha-carbon positions, but hydroxylates the alpha-carbon of the tyrosine part and the nitrogen of the glycine part (PubMed:27390873).  The next steps involve an alpha,beta-elimination reaction catalyzed by tcpI, a methylation by the methyltransferase tcpN the action of the four enzyme cascade tcpG/K/J/I (PubMed:27390873).  Due to a dysfunctional cytochrome P450 monooxygenase tcpC, the pathway leads to the biosynthesis of probable non-toxic metabolites lacking the reactive thiol group (PubMed:27390873).
What are the official names of this protein?
Probable aminotransferase tcpI, Thioclapurine biosynthesis protein I.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein: SAP30_DROPS
Sequence: MNNGFSTGEEDSRGHADQTCCLIDDMERCRNQAGYASYSKRIQKTVAQKRLRLSSDPSAQHIYICDHHKERIQSVRTKRRRKDSEDDSNETDTDLHEFPDLYQLSVSTLRRYKRHFKVQTRQGMKRAQLADTIMKHFKTIPIKEKEIITFFVYMVKMGTNKLDQKNGIGNDTT
What is the function of this protein?
Component of the class 1 Sin3A-histone deacetylase (HDAC1/Rpd3) complex (HDAC).  Appears to be a non-essential subunit of this complex which is not required for cell cycle regulation of progression through the G2 phase of the cell cycle (By similarity).
What are the official names of this protein?
Histone deacetylase complex subunit SAP30 homolog.
What is the protein family that this protein belongs to?
Belongs to the SAP30 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RH50_ORYSJ
Sequence: MEVAGAQAGILPLLLRHPASLRGSLSLSCGGARRSWAAAAATAEGGGGEEGRGYERVPMDTPGAYRLVDRATGRSVIVWGGTDDVSMPSPAVLSTTTRVPDRPKENGRSTSIGNFGRLKAQKVKVLARRSAHLKREDSGRISTSRFSESPSDESDEDGTYFERDRARNTRQNSRSRDDKTRGAHSLNSVLRQYRGADDLDFPGSEATSGSKRWGNISDVTFGRQNQRQKGPLDSGFFSRRSFKEIGCSDEILGALRSFGFPRPSHIQAMAYRPVLEGKSCIIGDQSGSGKTLAYLCPVVQNLRKEEVEGLHRSSPRNPRVVVLTPTAELASQVLNNCRSISKSGVPFRSMVATGGFRQKTQLESLDQELDVLIATPGRFLYLLQEGFVQLNNLRCVVLDEVDILYGEESFEQVLHQLITVAPLTTQYLFVTATLPLDIYNKVVETFPDCELIMGPGVHRTSSRLEEILVDCSGDDNEEKNPETAFSNKKSALVKIIEESPVRKTIIFCNKIETCRKVENALRRVDRKASQIKVLPFHAALDQQQRIANIKEFLNKQTADSMFLVCTDRASRGIDFANVNHVVLFDYPRDPSEYVRRVGRTARGASGNGKAFVFAVGKQVSLARRVMERNIKGHPLHDVPCV
What is the function of this protein?
Probably involved in resistance to biotic and abiotic stresses.  Confers tolerance to oxidative stress and mediates pathogenesis-related (PR) genes expression.  Exhibits RNA-dependent ATPase and ATP-dependent RNA helicase activities in vitro.
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 50.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family.