PharMolix/UniProtQA huggingface dataset:
Protein: RS10_CHLMU
Sequence: MKQQKQRIRIRLKGFDQGQLDQSTANIVETAKRTGARVVGPIPLPTKREVYTVLRSPHVDKKSREQFEIRTHKRLIDILDPTGKTIDALKMLSLPAGVDIKIKAA
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: GLV7_ARATH
Sequence: MTTLSKILCVLIILLLCFSFRYSLHEDGNQQSSRDFVSTAKAIKYGDVMKKMIRGRKLMMASGEKEEAETKMKRGNRETERNSSKSVEEDGLVAYTADYWRAKHHPPKNN
What is the function of this protein?
Signaling peptide (root growth factor) that maintains the postembryonic root stem cell niche (PubMed:20798316, PubMed:23370719).  Regulates the pattern of root growth and lateral root development by modulating the length and the number of cortical cells in the root apical meristem (RAM), and the anticlinal asymmetric cell divisions in lateral root initiation cells (By similarity).
What are the official names of this protein?
Protein GOLVEN 7, CLAVATA3/ESR (CLE)-related protein CLEL3, CLE-Like protein 3, Root meristem growth factor 3, AtRGF3.
What is the protein family that this protein belongs to?
Belongs to the RGF family.
What are the subcellular locations of this protein?
[GLV7p]: Secreted.
Protein: HNRL1_HUMAN
Sequence: MDVRRLKVNELREELQRRGLDTRGLKAELAERLQAALEAEEPDDERELDADDEPGRPGHINEEVETEGGSELEGTAQPPPPGLQPHAEPGGYSGPDGHYAMDNITRQNQFYDTQVIKQENESGYERRPLEMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKKSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGQALYPHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILMMVGLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQCLNRLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKRTDEEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAGPPPEKRFDNRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQNRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASTYNKNSNIPGSSANTSTPTVSSYSPPQPSYSQPPYNQGGYSQGYTAPPPPPPPPPAYNYGSYGGYNPAPYTPPPPPTAQTYPQPSYNQYQQYAQQWNQYYQNQGQWPPYYGNYDYGSYSGNTQGGTSTQ
What is the function of this protein?
Acts as a basic transcriptional regulator.  Represses basic transcription driven by several virus and cellular promoters.  When associated with BRD7, activates transcription of glucocorticoid-responsive promoter in the absence of ligand-stimulation.  Also plays a role in mRNA processing and transport.  Binds avidly to poly(G) and poly(C) RNA homopolymers in vitro.
What are the official names of this protein?
Heterogeneous nuclear ribonucleoprotein U-like protein 1, Adenovirus early region 1B-associated protein 5, E1B-55 kDa-associated protein 5, E1B-AP5.
Protein: RL3_STRA1
Sequence: MTKGILGKKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETDGYEAVQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAELSVEQFEAGDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRLAGRMGGNRVTVQNLEIVQVIPEKNVVLIKGNVPGAKKSLITIKSAVKAAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RL40_METKA
Sequence: MAKFPEAEARIFNKLICMKCNARNPPDATKCRKCGYKGLRPKAREPRGG
What are the official names of this protein?
50S ribosomal protein L40e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL40 family.
Protein: YJ11A_YEAST
Sequence: MESQQLSQHSHISHGSACASVTSKEVHTNQDPLDVSASKTEECEKASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPGTY
What is the function of this protein?
Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome.  The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules.  CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity).
What are the official names of this protein?
Transposon Ty1-JR1 Gag polyprotein, Gag-p49, Transposon Ty1 protein A, TY1A, TYA, p58.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_VIBPA
Sequence: MTETFQHISVLLNESIDGLAIKPDGIYIDGTFGRGGHSRTILSKLGPNGRLYSIDRDPQAIAEAGKIDDPRFTIIHGPFSGMAQYAEEYDLVGKVDGVLLDLGVSSPQLDDAERGFSFMKDGPLDMRMDPTSGIPVSQWLMEADLDDITWVIREFGEDKHARRIARAIVEYRENEENEPMVRTGQLAKLISEAAPKSFKEKKHPATRAFQAFRIYINSELEEIDTALKGAARILAPEGRLSVISFHSLEDRMVKRFIRKESKGPEVPHGIPLTEAQIKELGSANMKTVGKAIKPSKQEIDMNPRSRSSVLRIAEKL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DF251_ARATH
Sequence: MRCVTSFVVFCILMFFVLNIFTVEVKAQRLVPLCKTIGYENPGKCPADGNKFCRRKLDDRYVKYKRCDCQDTKGRKQNHHRCICYMKLPCNQ
What are the official names of this protein?
Putative defensin-like protein 251, Putative S locus cysteine-rich-like protein 12, Protein SCRL12, SCR-like protein 12.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: HPPD_PIG
Sequence: MTSYSDKGEKPERGRFLHFHSVTFWVGNAKQAASYYCSKIGFEPLAYKGLETGSREVVSHVVKQDKIVFVFSSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAIIVREEVCCAADVRGHHTPLDRARQVWEGTLVEKMTFCLDSRPQPSQTLLHRLLLSKLPKCGLEIIDHIVGNQPDQEMESASQWYMRNLQFHRFWSVDDTQIHTEYSALRSVVMANYEESIKMPINEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRSLRERGVEFLAVPFTYYKQLQEKLKSAKIRVKESIDVLEELKILVDYDEKGYLLQIFTKPMQDRPTVFLEVIQRNNHQGFGAGNFNSLFKAFEEEQELRGNLTDTDPNGVPFRL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
What are the official names of this protein?
4-hydroxyphenylpyruvate dioxygenase, 4-hydroxyphenylpyruvic acid oxidase, 4HPPD, HPD, HPPDase.
What is the protein family that this protein belongs to?
Belongs to the 4HPPD family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein.
Protein: RM16_MARPO
Sequence: MLYPKRTKFRKYQKGRCKGCKADGTQLCFGKYGIKSCEAGRISYQAIEAARRAISRKFRRNSKIWVRVFADIPITSKPAEVRMGKGKGNTKGWIARVLKGQILFEMDCVSLSNAQQAATLAAHKLGLSIKFFKWS
What are the official names of this protein?
60S ribosomal protein L16, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CTPAL_STAS1
Sequence: MSESKDTTEVNQEVNEKASSQSTKKQINFKRSHFIIILIVTILVTAMIAVFATIGISHWTSGLNSDQRDEMKKVEQVYQTLDDEYYKDTSSEELGTAAIDGMVKKLDDPYSDYMTKKETKSFNEDVSGDFVGIGAEMQKKGNQIQITSPMKQSPAEKAGIQPKDVVTKVNGKSIKGQPLEAIVKKVRGKQGTKVTLTIERGGQAHDITIKRDKIHVKSVEYQKHGDVGVFTINKFQNSTSGELKSAIIKAHKDGIRKIVLDLRNNPGGLLDEAVKMANIFIDKNETVVQLEKGKHKEAIKASNDASKEAKDMDVSILVNKGSASASEVFTGAMKDYNKAKVYGSKTFGKGIVQTTREFEDGSLLKFTNMKWLTPKSHYIHGKGITPDKKIEEPAYQSLNVIPSNKTYQLGDDDKNVKTMKVGLNVLGYHINNHSTEFDSELEDALKSFQKKNNLDVNGTFNKSTNEKFTQQLVEKANKEDTVLNELLKKLN
What are the official names of this protein?
Probable CtpA-like serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S41A family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PYRD_DICDI
Sequence: MEWPINKPIYDINKSWEDNLENGPFIEGYKKVDRNDNKDPSKYIDFLGQKLASPIGVPAGPLLNSQWVKFALEAGFDLPTYKTIRSHEHFGHPVPNVMYLDLESEDKQFTKSDSGSTLHATQTIPTTMDQLAITNSFGMPSMGKEYLYKDIALAHSYLGSGQSMIVSITGTASSAHDFLQDFVDTVRIACDAGAKMVEVNYSCPNVVTGEGQIYHNPDAVYEISSTLVKELSSKNIPLIIKVGVMDDLEKMERLFQQAERAGVAAIAGINTLSMKVTDKITGEPSLGASRLTSGVCGAPIRSAALDWVSTASSIIKKQNSKLKLLGCGGIVKPEHFDDFLNSGADIAMSATGLMWDPYIAMKWHNNNKNN
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate (PubMed:2996629).  Participates in the pyrimidine biosynthetic pathway (PubMed:2996629).
What are the official names of this protein?
Dihydroorotate dehydrogenase, DHOD, DHODase, DHOdehase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family.
Protein: Y885_CHLPD
Sequence: MVNEFEKLQSGKLLLASANLLESNFKRTVLIICEHNESGSLGFILNRPMEFKVCEAVAGFEEIEEPLHMGGPVQVDTVHFLHSRGDIIDGATEIFPGLFWGGDKNQVSFLLNTGVMQPSEIRFFLGYSGWSAGQLEEEFEIGSWYIAEASRDVIFSDAYERMWSRSVRSKGGEYQIVANAPELPGLN
What are the official names of this protein?
UPF0301 protein Cpha266_0885.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: AKR1_CANGA
Sequence: MEDNSEQASVSSQASMRPLVSDNGDREAGAGVEVNIANDNDTSVGVDGENGNEDDDPILSKYHNACQRGDLEVVREMIHGGQVNVSSDADREGVTGLHWAAINNRLNVVDFLVREGANVESKAGALEATPLHWAARYGFVYVVDYLLQHGASATTTDKQGFNLLHLSVNSSNIMLVVYVLFFVVSKGIIDIDYVDPKGRTALLWAAYQGDSLTVAALIKFNASVKIADEGGFTPLHWGTVKGQPHVLKYLIQDGADFFQKTNDNKDCFVIAEEMSNTHSFQEALRHNNFDKNGYPINKLVKRDDHAKIITFLIPLLVLGFAFFGFSHLHILFALPVIILLLLASNKFIKSFLLPSYETKGTNSASLLKSPLIAGILFGSIFWLAFVWILRILPYTFTKRPLGNLTFCAILCFVCYSLFLLAFSDPGHIGSENDHEKIRETISNLLKEGKFDTRSFCLETWVRKPLRSKYSYLNDALILRFDHYCPWIYNDVGLKNHKLFIFFILALELGIFSFVKVCLKYFDELDMDGDCFILGDDDLCSGLIGDRFTFLIMTWACIQAVWIFSLVIVQLFQITKGLTNSELNALIREGRRVDIDSQTHNEFFNTVPEGFINNKDTEEEAAPPVRNNTNERISTTFSGNLPKPRTCMGMICAVTGLHQCVAIIKDTFGIARHGSSRSTNTRSLLSSISTDYGWRRNWCDFWLLSDTNTPLWKRIFFSPPSTKALLNGKEADYATLYEVPNKNHGSVSQLQELQDPLSEIDDMV
What is the function of this protein?
Palmitoyltransferase specific for casein kinase 1.
What are the official names of this protein?
Palmitoyltransferase AKR1, Ankyrin repeat-containing protein AKR1.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
What are the subcellular locations of this protein?
Early endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: EF2_ASHGO
Sequence: MVAFTVDQIRSLMDKVTNVRNMSVIAHVDHGKSTLTDSLVQRAGIISAAKAGEARFTDTRKDEQERGITIKSTAISLFSEMSEEDVKDIKQKTEGNSFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDTVEGVCVQTETVLRQALGERIKPVVVINKVDRALLELQVSKEDLYQSFSRTVESVNVIISTYADEVLGDVQVYPQKGTVAFGSGLHGWAFTIRQFANRYSKKFGVDREKMMERLWGDSYFNPKTKKWTNKDRDADGKPLERAFNMFVLDPIFRLFAAIMNFKKDEIPVLLEKLEIALKSDERDLEGKALLKVVMRKFLPAADALLEMIIMHLPSPVTAQNYRAEQLYEGPSDDPACIAIKNCDPKADLMLYVSKMVPTSDKGRFYAFGRVFSGTVKSGQKVRIQGPSFTVGKKEDLFIKAIQRAVLMMGRFVEPIDDCPAGNIVGLVGIDQFLLKTGTLTTFESAHNMKVMKFSVSPVVQVAVEVKNANDLPKLVEGLKRLSKSDPCVLTYMSESGEHIVAGTGELHLEICLQDLENDHAGIPLKISPPVVAYRETVEGESSQVALSKSPNKHNRIYLKAQPIDEEVSLAIEGGKINPRDDFKARARVMADEYGWDVTDARKIWCFGPDGNGPNLVVDQTKAVQYLNEIKDSVVSAFQWATKEGPIFGEQMRSVRINLLDVTLHADAIHRGAGQIMPTMRRATYAGFLLAEPKIQEPVFLVEIQCPEQAVGGIYSVLNRKRGQVVSEEQRPGTPLFTVKAYLPVNESFGFTGELRQATGGQAFPQMVFDHWATLGTDPLDPTTKAGEIVVEARKRHGLKENVPGWQEYYDKL
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AZOR2_TRIV2
Sequence: MANILHIDSSPRGDRSISRKLSYEFLTSWKDTHPGDTVTYRDLGHNPVPHVDEPWIAAAFSSPDSHTPELKAAIELSDTLIDEFLAADRFVFGVPMYNLNIPSTFKAYIDQIVRVGRTFSVDANGYKGLVDSSKKVLIITSRGGSYPPGTPYAAYDYQEPYLRAILGFMGLTDVTFIHAESLNMGEDAREKSLADAKDAIAQAVANW
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase 2, Azo-dye reductase 2, FMN-dependent NADH-azo compound oxidoreductase 2, FMN-dependent NADH-azoreductase 2.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: UL07_HCMVM
Sequence: MASDVGSHPLTVTRFRCRVHYVYNKLLILTLFAPVILESVIYVSGPQGGNVTLVSNFTSNISARWFRWDGNDSHLICFYKRGEGLSTPYVGLSLSCAANQITIFNLTLNDSGRYGAEGFTRSGENETFLWYNLTVKPKPLETTPASNVTTIVTTTSTVTDAKSNVTGNVSLAPQLRAVAGFSHQTPLENNTHLALVGVVVFLVLIVVCIMGWWKLLCSKSEL
What is the function of this protein?
Plays a role in modulating the host immune response and affecting host cytokine production.  Structurally and functionally homolog of host CEACAM1, induces endothelial cell angiogenesis.
What are the official names of this protein?
CEACAM1-like protein UL7.
What is the protein family that this protein belongs to?
Belongs to the RL11 family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane; Single-pass membrane protein.
Protein: PARP1_MAIZE
Sequence: MAAPPKAWKAEYAKSGRASCKSCRSPIAKDQLRLGKMVQASQFDGFMPMWNHARCIFSKKNQIKSVDDVEGIDALRWDDQEKIRNYVGSASAGTSSTAAPPEKCTIEIAPSARTSCRRCSEKITKGSVRLSAKLESEGPKGIPWYHANCFFEVSPSATVEKFSGWDTLSDEDKRTMLDLVKKDVGNNEQNKGSKRKKSENDIDSYKSARLDESTSEGTVRNKGQLVDPRGSNTSSADIQLKLKEQSDTLWKLKDGLKTHVSAAELRDMLEANGQDTSGPERHLLDRCADGMLFGALGPCPVCANGMYYYNGQYQCSGNVSEWSKCTYSATEPVRVKKKWQIPHGTKNDYLMKWFKSQKVKKPERVLPPMSPEKSGSKATQRTSLLSSKGLDKLRFSVVGQSKEAANEWIEKLKLAGANFYARVVKDIDCLIACGELDNENAEVRKARRLKIPIVREGYIGECVKKNKMLPFDLYKLENALESSKGSTVTVKVKGRSAVHESSGLQDTAHILEDGKSIYNATLNMSDLALGVNSYYVLQIIEQDDGSECYVFRKWGRVGSEKIGGQKLEEMSKTEAIKEFKRLFLEKTGNSWEAWECKTNFRKQPGRFYPLDVDYGVKKAPKRKDISEMKSSLAPQLLELMKMLFNVETYRAAMMEFEINMSEMPLGKLSKENIEKGFEALTEIQNLLKDTADQALAVRESLIVAASNRFFTLIPSIHPHIIRDEDDLMIKAKMLEALQDIEIASKIVGFDSDSDESLDDKYMKLHCDITPLAHDSEDYKLIEQYLLNTHAPTHKDWSLELEEVFSLDRDGELNKYSRYKNNLHNKMLLWHGSRLTNFVGILSQGLRIAPPEAPVTGYMFGKGLYFADLVSKSAQYCYVDRNNPVGLMLLSEVALGDMYELKKATSMDKPPRGKHSTKGLGKTVPLESEFVKWRDDVVVPCGKPVPSSIRSSELMYNEYIVYNTSQVKMQFLLKVRFHHKR
What is the function of this protein?
Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism.  This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks (By similarity).
What are the official names of this protein?
Poly [ADP-ribose] polymerase 1, PARP-1, NAD(+) ADP-ribosyltransferase 1, ADPRT-1, Poly[ADP-ribose] synthase 1, Protein ADP-ribosyltransferase PARP1.
What is the protein family that this protein belongs to?
Belongs to the ARTD/PARP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DCDA_BUCAI
Sequence: MPKPLNNTENNLNTNRIKDLIKKYSPPFWVYDADIIYKKINLLRKFDVIRFAQKSCSNINILRLMKNKNVKIDAVSLGEIERALLSGFKPSTNEIIFTADILDEETLLKVAKYKIPVNAGSLDMLKQLGKISPGHHVWLRINPRFGYGHSKKTNTGGENSKHGIWHPEQAIPIIKKYKLKLIGLHMHIGSGVNYLHLKKVSQAMIKYAFQLNQKISSISVGGGLPIPYKFNDQPIDIKKYFMLWDIARKKISKFLGEKIELEIEPGRFLVAESGILISKVWATKKMGNKNFVLVDVGFNDLMRPTMYGSYHHISVIYGDDRKMNEKETIDTVVAGPLCESGDIFTQKEGGTVQTRKLPTIKVGDYLIFHDTGAYGAAMSSNYNTRPLIPEILLKNNDSIVIRRRQTIEEILNLEK
What is the function of this protein?
Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.
What are the official names of this protein?
Diaminopimelate decarboxylase, DAP decarboxylase, DAPDC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
Protein: ARI5A_HUMAN
Sequence: MAAPVKGNRKQSTEGDALDPPASPKPAGKQNGIQNPISLEDSPEAGGEREEEQEREEEQAFLVSLYKFMKERHTPIERVPHLGFKQINLWKIYKAVEKLGAYELVTGRRLWKNVYDELGGSPGSTSAATCTRRHYERLVLPYVRHLKGEDDKPLPTSKPRKQYKMAKENRGDDGATERPKKAKEERRMDQMMPGKTKADAADPAPLPSQEPPRNSTEQQGLASGSSVSFVGASGCPEAYKRLLSSFYCKGTHGIMSPLAKKKLLAQVSKVEALQCQEEGCRHGAEPQASPAVHLPESPQSPKGLTENSRHRLTPQEGLQAPGGSLREEAQAGPCPAAPIFKGCFYTHPTEVLKPVSQHPRDFFSRLKDGVLLGPPGKEGLSVKEPQLVWGGDANRPSAFHKGGSRKGILYPKPKACWVSPMAKVPAESPTLPPTFPSSPGLGSKRSLEEEGAAHSGKRLRAVSPFLKEADAKKCGAKPAGSGLVSCLLGPALGPVPPEAYRGTMLHCPLNFTGTPGPLKGQAALPFSPLVIPAFPAHFLATAGPSPMAAGLMHFPPTSFDSALRHRLCPASSAWHAPPVTTYAAPHFFHLNTKL
What is the function of this protein?
Binds to AT-rich stretches in the modulator region upstream of the human cytomegalovirus major intermediate early gene enhancer.  May act as repressor and down-regulate enhancer-dependent gene expressison (PubMed:8649988).  May positively regulate chondrocyte-specific transcription such as of COL2A1 in collaboration with SOX9 and positively regulate histone H3 acetylation at chondrocyte-specific genes.  May stimulate early-stage chondrocyte differentiation and inhibit later stage differention (By similarity).  Can repress ESR1-mediated transcriptional activation; proposed to act as corepressor for selective nuclear hormone receptors (PubMed:15941852).  As RNA-binding protein involved in the regulation of inflammatory response by stabilizing selective inflammation-related mRNAs, such as IL6, STAT3 and TBX21.  Binds to stem loop structures located in the 3'UTRs of IL6, STAT3 and TBX21 mRNAs; at least for STAT3 prevents binding of ZC3H12A to the mRNA stem loop structure thus inhibiting its degradation activity.  Contributes to elevated IL6 levels possibly implicated in autoimmunity processes.  IL6-dependent stabilization of STAT3 mRNA may promote differentiation of naive CD4+ T-cells into T-helper Th17 cells.  In CD4+ T-cells may also inhibit RORC-induced Th17 cell differentiation independently of IL6 signaling.  Stabilization of TBX21 mRNA contributes to elevated interferon-gamma secretion in Th1 cells possibly implicated in the establishment of septic shock (By similarity).  Stabilizes TNFRSF4/OX40 mRNA by binding to the conserved stem loop structure in its 3'UTR; thereby competing with the mRNA-destabilizing functions of RC3H1 and endoribonuclease ZC3H12A (By similarity).
What are the official names of this protein?
AT-rich interactive domain-containing protein 5A, ARID domain-containing protein 5A, Modulator recognition factor 1, MRF-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: ENGB_AERS4
Sequence: MDTQTLNFNKVHFVTSAPDIRHLPNDGGVEIAFAGRSNAGKSSALNTLTKHKNLARTSKTPGRTQLINLFELEPGKRLVDLPGYGYAQVPLEMKLKWQKSLAEYLQRRESLKGLVILMDIRHPLKDTDMNMLEWSSHRELPVMLLLTKADKLSPGPRNNQVIKVRQAIADLGPQIQVEAFSSLNNIGVEKLAQTLSGWYLAGADEIADNDEQEQVEE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: CH601_PROM2
Sequence: MAKQLSFSNESREALEKGVNFVANAVKVTIGPKAKNVVIDRKFGSPDIVSDGSTVAKEIEIENPISNLGAKLIEQVASKTKESAGDGTTTATILTQKMVQEGLKNIASGASPIELKKGMEVGLDFVLEKLSSKSISLSGSDIQKVATVSAGGDEEIGSIISKAMDIVTSDGVINVEESQSLDTELDITEGMSFDRGYSSPYFVTDQERQICELENPKILITDQKISTLVDLVPILEEIQKSGSPFLILAEDIEGEALTTLVLNKNSGVLNVASVRAPLFGERRKAALEDIAILTGAKLISEDKSMTLDKVSINDLGKAKKITITKDKTTIIAFEDTKDLVKARVEKLKREVDMTDSEYDQDKINERIAKLAGGVALIKVGAATETEMKYKKLRIEDSLNATKAAIEEGVVPGGGQTLIEISDDLLNLSQTSSDDLRTGINIIKEALLEPTKQIAKNAGFNGDVVIAEIKRLNKGFNANSGKYEDLKNSGILDPTKVIRLALQDSVSIAAMLLTTEVAIADIPEPEPAAPGGPSGDPMGGMGGMGMPGMGGMGMPGMGGMGMPGMGGMGMPGMGGMGMPGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1424_STRR6
Sequence: MTKKQLHLVIVTGMGGAGKTVAIQSFEDLGYFTIDNMPPALLPKFLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVARYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFSDQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVMNHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKNWSVNEGHRDKDRRKETVNRS
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein spr1424.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: RR2_GRATL
Sequence: MSIVSLSELLEAGAHFGHQARRWNPRMFPYIYTERNGIHIIDLVQTAQLLTEACQFIRDASQEGKKFLFLGTKRQAAGVIAEQAIRSNSYYVNQRWLGGMLTNWMTIKSRVERLQRLEMDEQAGLIDMLPKKEAAINRRELDKLRKNLNGIKNMSRLPDFIVVVDQKRETTAIQECIKLGIPIICILDTNCNPEIIDIPIPANDDAIRSIKLIISRIADSIIEGSTYALNK
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRUB_LEPIC
Sequence: MNRSDLLENPRTQTESGFLLIHKPVGMTSSDLVVTVRKKLGFKKVGHTGTLDRAASGLMILPIGSCTSFSSVFLEKEKSYEAWVRPGESTDSGDKEGEILESLSKEQTETWFQEHQEKLRDLFEQVPTWETQEAPEVSALKVNGRRRSDLFREGVALVPAVRKIKIYRYELGEFSPESISFQIRVSAGTYIRKIVMDISDRIGFPLRLEKLVRTSIGKLNLNQADSYESLLDGKIKIHPPETILDFPTVEVPDTEVRNVLNGRKIKLEWIPVNEFLLVSPEEEILAWCKKEEHGIHELDYKYLRVFPKN
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: TX1B_PHOKE
Sequence: AELTSCFPVDHECDGGASNCNCCGDDVYCA
What is the function of this protein?
Lethal neurotoxin.  Causes spastic paralysis and death in mice in 4-6 min after intracerebroventricular injection at dose levels of 1. 5 ug per mouse.
What are the official names of this protein?
U5-ctenitoxin-Pk1b, U5-CNTX-Pk1b, Neurotoxin PKTx16C1, Neurotoxin PKTx1B.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 04 (omega-agtx) family. 02 (Tx1) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MDH_BREVE
Sequence: AXAKIALIGAGMIGGTLAA
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.