PharMolix/UniProtQA huggingface dataset:
Protein: Y1380_ACTP2
Sequence: MEAVERIENPCGIRLRIFLQPKASRDQIVGLHDNELKIAITALPVDGAANAHLLKYLSKLFKVPKSSIVLEKGELQRHKQLFVPEPKLIPKEIEALL
What are the official names of this protein?
UPF0235 protein APL_1380.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: LIS1_KOMPG
Sequence: MSDILTKKQDIELRRAVIQYLRYFVPEFAQDTAVNTISRLLLDADLNKFDNEIQRMIPKQYLEKKWTAVLRLHRKVEELERTIGYQSNKVEIELQSQPHSDITSNSLDRINWVPGIEPFQKLNMHNGHPVTAIDIHPFQPIMATASQDGTIVIWNLLNLTEPQQIIRNAHTRSINTIKFMNQEVMDGHSTKKNRLLLATGSSDLLIKIWDIEDSANLKALRTLTGHENIISCLCFHPTEPSKLVSCSKDKTTKVWDTRTGSIVLSFVGHSNWVRSVDINRTGEFTLTSSNDHSIRLSSLLTGTGIGLMIGHEQVVEKVKFLPMACNKYLDHIAGVKFQNELKINDDNYNKVDYKYCISGGRDNSVCIWLLPLPLIRSDGTMHPSTNPEGKLILKLTEHKSWVKDIAIHPNSRFIISVGDDRKINIWDLGLLLESNLLQPFRSISTQGFPSTLCMAKPVIKDQESDDLILLNEAMRCYLAVGHSDGTVTLWKKNIQKEYIL
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  Plays a central role in positioning the mitotic spindle at the bud neck during cell division.  Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck.
What are the official names of this protein?
Nuclear distribution protein PAC1, Lissencephaly-1 homolog, LIS-1, nudF homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the plus ends of microtubules and the mitotic spindle poles.
Protein: CHED_METBF
Sequence: MGIGACALARSPVKIKTFGLGSCVVITLYDRQERIGGLVHTMLPSISDARIKDKPFKYTDSGIEHLATEILREGSPRKRFEAKLVGGAHMFENRNLNIGERNIKYAKNTLEKFEIPIISEDTGKNYGRTITLDTSTGDLLIRTILRADKII
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: S2538_PICST
Sequence: MTNAATDKSVASVARDVSTGKPGKSPDAAVHLLSGGLAGLTSAVTLQPFDLLKTRLQQQHSETSKLTIAGEIRKLSQLKELWRGAVPSALRTSVGAGLYFTTLSKMRAAVAQYNHRDSSVTSVLPKLLPMENLATGFVARAIVGYITMPITMVKTRFESNIYSYRTMGESIVGIYKDIGPDGVVHRSSLLNFFKGSVATLARDCPYAGLYVLFYEGFKNDVLVKVIPESVTGSDSRSSVINSSSAILAASVSTTITAPFDAIKTRLQLTKETSILKTTGILLREDGGVFNLFRGLSLRFGRKALSAGISWCIYEELIKSDFSQCRLFNKERLA
What is the function of this protein?
Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix.  Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix.
What are the official names of this protein?
Mitochondrial glycine transporter, Solute carrier family 25 member 38 homolog.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NU1C_LOBMA
Sequence: MIIYATEVQTINSFVRLESLKEVYGFIWIFVPIFSLVLGIITGVLVIVWLEREISAGIQQRIGPEYAGPLGILQALADGTKLLFKEDLRPSRGNTPLFSIGPSIAVISILLSYSIIPFSNHLVLADLNIGIFLWIAISSIAPIGLLMSGYGSNNKYSFLGGLRAAAQSISYEIPLTLCVLSISLLSNSLSTVDIVEAQSKYGFWGWNLWRQPIGFIIFLISSLAECERLPFDLPEAEEELIAGYQTEYSGIKFGLFYVASYLNLLISSLFVTVLYLGGWNISIPHISILKLFEGDQIFGTTIGIFITLAKTYLFLFISIATRWTLPRLRMDQLLNLGWKFLLPISLGNLLLTTSFQLFSL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic, NAD(P)H dehydrogenase subunit 1, NDH subunit 1, NADH-plastoquinone oxidoreductase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TPSTB_CAEEL
Sequence: MRAILDAHPDVRCGGETMLLPSFLTWQAGWRNDWVNNSGITQEVFDDAVSAFITEIVAKHSELAPRLCNKDPYTALWLPTIRRLYPNAKFILMIRDARAVVHSMIERKVPVAGYNTSDEISMFVQWNQELRKMTFQCNNAPGQCIKVYYERLIQKPAEEILRITNFLDLPFSQQMLRHQDLIGDEVDLNDQEFSASQVKNSINTKALTSWFDCFSEETLRKLDDVAPFLGILGYDTSISKPDYSTFADDDFYQFKNFYS
What is the function of this protein?
Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
What are the official names of this protein?
Putative protein-tyrosine sulfotransferase, Tyrosylprotein sulfotransferase, TPST.
What is the protein family that this protein belongs to?
Belongs to the protein sulfotransferase family.
Protein: PANB_PORGI
Sequence: MSTYQPEDTRKVTTHRLIEMKSRGEKISMLTAYDYSMAKLVDEAGMDVILVGDSASNVMAGNVTTLPITLDQMIYHGKSVVKAVKRALVVVDLPFGSYQGNSKEALCSAIRVMKETHADCIKLEGGEEVRESIVRILSAGIPIMGHLGLMPQSINKFGTYNVRAKEEAEAEKLLQDAHLLEELGCFALVLEKIPAELATRVASELSIPVIGIGAGGGVDGQVLVMHDMLGITEGFSPRFLRRYANLANEIDRALKHYIADVKSMDFPNKDEQY
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBP3_STRPU
Sequence: MKVSLLAVLLLSIVAATYGQGECGSNPCENGSVCRDGEGTYICECQMGYDGQNCDRFTGANCGYNIFESTGVIESPNYPANYNNRADCLYLVRIKGARVITFTIEDFATEIFKDAVEYGVGPVADFNQALATFEGNLTANNQVPPPFSVQGEQAWFIFSTDRNIPRKGFRITFSSDGDDCTPNPCLNGATCVDQVNDYQCICAPGFTGDNCETDIDECASAPCRNGGACVDQVNGYTCNCIPGFNGVNCENNINECASIPCLNGGICVDGINQFACTCLPGYTGILCETDINECASSPCQNGGSCTDAVNRYTCDCRAGFTGSNCETNINECASSPCLNGGSCLDGVDGYVCQCLPNYTGTHCEISLDACASLPCQNGGVCTNVGGDYVCECLPGYTGINCEIDINECASLPCQNGGECINGIAMYICQCRQGYAGVNCEEVGFCDLEGVWFNECNDQITIIKTSTGMMLGDHMTFTERELGVAAPTVMVGYPSNNYDFPSFGITVVRDNGRTTTSWTGQCHLCDGQEVLYTTWIESSMVSTCEEIKRANKVGQDKWTRYEQSFAPQPDA
What is the function of this protein?
Forms the apical lamina, a component of the extracellular matrix.
What are the official names of this protein?
Fibropellin-3, Epidermal growth factor-related protein 3, Fibropellin III, Fibropellin-c, SpEGF III.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: PSAJ_STAPU
Sequence: MQDVKTYLSTAPVLAAIWFGILAGLLIEINRFFPDALVLPYV
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MOAA2_MYCTO
Sequence: MTLTALGMPALRSRTNGIADPRVVPTTGPLVDTFGRVANDLRVSLTDRCNLRCSYCMPERGLRWLPGEQLLRPDELARLIHIAVTRLGVTSVRFTGGEPLLAHHLDEVVAATARLRPRPEISLTTNGVGLARRAGALAEAGLDRVNVSLDSIDRAHFAAITRRDRLAHVLAGLAAAKAAGLTPVKVNAVLDPTTGREDVVDLLRFCLERGYQLRVIEQMPLDAGHSWRRNIALSADDVLAALRPHFRLRPDPAPRGSAPAELWLVDAGPNTPRGRFGVIASVSHAFCSTCDRTRLTADGQIRSCLFSTEETDLRRLLRGGADDDAIEAAWRAAMWSKPAGHGINAPDFIQPDRPMSAIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase 2, Molybdenum cofactor biosynthesis protein A 2.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: SP110_KLULA
Sequence: MSSVMETPHAGKLKKYEFTPIGYAEEKRKEGIDLLKENGLKRSLESGSDLPAERKRVRNPSVVDETFSSTRLFNDTSFDETVPEGIIQERRPNSRKNLVDDLLIKDQETTENLTSNPLKETESSLKKLQMENYNLRIKCTSLLKFLNNISDDGEIVKNLEILDELDDLKVRYRQLNLDYTALQKQCDRIEDQNDEHEDIAKLKESNDKLKEELRSTKENLIDTDAQLQQLKDTIKSLENKIFNMRTEQTEKECQHGMQVDLLQSKINETSTSLTSKERECSDLKEKIKWLTSQLQEFDHQSGSLLDLQSTLDSKNEAIRNLEAQLQRNEHQRQSLEREVSLLQEELSSIRETHQKIITHKDQQIKQLTENLSSSDSEAVKRLNELSSERLRLLETNKSLKFSEKDLKQTVKSLEDQLNSCQEELHASQDKHKEKVSELLRKQLPYTSSEVEAMRQELLEMRKSNDILKTENNSLSRRLDNLIRQSPSKKSVEVDIQRKNNEIRALRSTVKDLEHELQDVTSNVSKLKENHKEEIQKLRKQVNPDLPTDVLEEKSKLQNRISLLQMELNSIKDTKEKELAMWRRKYETIRRSNEELLQEGKDQSGQLSNILNEKDKEILQLQSRFNSLLTEKNSLLNELSKVRSHKDDYKEELKKNQSRLEFITKEFVKLKDASKQAENSEDAKDILNNKWYSKYQSMKDKFLGELKSLQDENLELQKSLLKQKANPNSTAEVFSKTTEKGTLKDEIDYYRLKYANEVKQNNDLKTMNQYLNRVLRASSQHVKLDILKLQNEVPVYNPYADIPFHNMRFSHQKIKFKTVALLVLSCIRMKTTIEARRWDRQRLDYLKRKIVLNQDNISW
What is the function of this protein?
Component of the spindle pole body (SPB) required for the proper execution of spindle pole body (SPB) duplication.  Potential role in cross-linking filaments or anchoring other molecules.  It is essential for growth (By similarity).
What are the official names of this protein?
Spindle pole body component 110, Spindle pole body spacer protein SPC110.
What is the protein family that this protein belongs to?
Belongs to the SPC110 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Tightly associated with the nucleus. It is present in a granular pattern that excludes the nucleolus.
Protein: PUR7_CHLSY
Sequence: MELGYVLTEGKTKIVYAHPTDPDLAILYHKDGITAGDGARRSVIEGKGELAGQTTANVFRLLNRAGIATHFVDAPEPRLTVVRRCRMIPLEVVMRRLPAGSYLRRHPEAAGQRFDPPLVEFFLKDDARHDPQIAPQEIIAQGIATPAEVEQMTDTGRKVFVTLEAAWQQLDVTLVDLKIEFGRTAQGDLLVADVIDNDSWRIWPSGDPAQMLDKQVYRNAQVVDEALLADVRARYALVAELTGRWGAGS
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: TTF2_DROME
Sequence: MSSENSEYYSDKEEDSVVNNSSLGRSRKSSRLSKSSRLSKSSRPSSAGVVIDETQSEEEESQSSETAESEKSDESDNSQNSQESEDSEDDSVRPSARNTKRKPLGIPSDSEDEEDELEQRALSPSTRMSITGVRPQDLSDDDSEIEYSDEVQEGPTEAPTAEAVVPRYTTQFAGNIQNDLHSTIGAADSEVLDDSSGSDVLILSNKETPIEILSSTDDDATTNKENMSGPPFERPSKSLSPRSSAGASVVKTSKNLSQPTIQAVLKQKTSPAAPRRSRIKSEDQKVVSQVVYDEEMRKLAEKRVQVSDAEKLFEKVAHKLPDKGSQIMKRIDTLRRELAMDEQWISALRVQQSNVPAVRVVKPTLNPPRAPSIDTLDWDELSEAVNEIKPVYTGAQGMATFNNQKALTLESLKDLHVSLEDLPGPEVLAEDPVGLKVSLMNHQKHALAWMSWRERKLPRGGILADDMGLGKTLTMISSVLACKNGQEMSEGKDESSDSDSEDDKNKKRKSVTGWKSKGRKDTRRGGTLVVCPASLLRQWESEVESKVSRQKLTVCVHHGNNRETKGKYLRDYDIVVTTYQIVAREHKSLSAVFGVKWRRIILDEAHVVRNHKSQSSLAVCDLRGKYRWALTGTPIQNKELDVYALLKFLRCSPFDDLHTWKKWIDNKSAGGQNRLNLLMKSLMLRRTKAQLQSDGKLNSLPNKELRLIEISLDKEEMNVYQTVMTYSRTLFAQFLHQRAERETDFNYRSDANKPTYNQIKDPNGAYYKMHEKFARMAGSKKEVKSHDILVLLLRLRQICCHPGLIDAMLDGEESQTMGDHSSDSDTPEIDLLAQLNKLAITDTSTDGQQSVANAGDDGPPLLPDEARIAKASKNLLKRSNPVFNLHRPSSKINMVIQILKTSILKSSDDKAIVVSQWTSVLDILRDHLSKDGVATLSLNGTIPVKNRQDIVNEFNDRNNQKRVLLLSLTAGGVGLNLIGANHLLLLDLHWNPQLEAQAQDRIYRVGQKKNVIIYKFMCVDTVEQRIKGLQDKKLDLADGVLTGAKVSSKLTIDDLKGLFGM
What is the function of this protein?
DsDNA-dependent ATPase which acts as a transcription termination factor by coupling ATP hydrolysis with removal of RNA polymerase II from the DNA template.
What are the official names of this protein?
Transcription termination factor 2, Protein lodestar, RNA polymerase II termination factor, Transcription release factor 2.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MGT_STAA8
Sequence: MKRSDRYSNSNEHFEHMKHEPHYNTYYQPVGKPPKKKKSKRILLKILLTILIIIALFIGIMYFLSTRDNVDELRKIENKSSFVSADNMPEYVKGAFISMEDERFYNHHGFDLKGTTRALFSTISDRDVQGGSTITQQVVKNYFYDNDRSFTRKVKELFVAHRVEKQYNKNEILSFYLNNIYFGDNQYTLEGAANHYFGTTVNKNSTTMSHITVLQSAILASKVNAPSVYNINNMSENFTQRVSTNLEKMKQQNYINETQYQQAMSQLNR
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation using lipid-linked disaccharide-pentapeptide as the substrate.
What are the official names of this protein?
Monofunctional glycosyltransferase, MGT, Peptidoglycan TGase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: HEMH_SHISS
Sequence: MRQTKIGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTSRLLWWPLLRGVILPLRSPRVAKLYASVWMEGGSPLMVYSRQQQQALAQRLPETPVALGMSYGSPSLESAVDELLAEHVDHIVVLPLYPQFSCSTVGAVWDELARILARKRSIPGISFIRDYADNHDYINALANSVRASFAKHGEPDLLLLSYHGIPQRYADEGDDYPQRCRTTTRELASALGMAPEKVMMTFQSRFGREPWLMPYTDETLKMLGEKGVGHIQVMCPGFAADCLETLEEIAEQNREVFLGAGGKKYEYIPALNATPEHIEMMANLVAAYR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACADM_CAEEL
Sequence: MLSRIATSSLGLSRSATGVIATQSRQISFDLSETQKEIQDAALKFSKDVLVPNAAKFDESGEFPWEIVRQAHSLGLMNPQIPEKYGGPGMTTLETALIVEALSYGCTGIQLGIMGPSLAIAPVYISGNEEQKKKYLGALAAEPIIASYCVTEPGAGSDVNGVKTKCEKKGDEYIINGSKAWITGGGHAKWFFVLARSDPNPKTPAGKAFTAFIVDGDTPGITRGKKEKNMGQRCSDTRVITFEDVRVPAENVLGAPGAGFKVAMEAFDMTRPGVAAGALGLSWRCLDESAKYALERKAFGTVIANHQAVQFMLADMAVNLELARLITYKSANDVDNKVRSSYNASIAKCFAADTANQAATNAVQIFGGNGFNSEYPVEKLMRDAKIYQIYEGTSQIQRIVISRMLLGHFAQNGTSRI
What is the function of this protein?
This enzyme is specific for acyl chain lengths of 4 to 16.
What are the official names of this protein?
Probable medium-chain specific acyl-CoA dehydrogenase 10, mitochondrial, MCAD.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: Y13F_BPT4
Sequence: MFPTYSKIVEVVFSQIIANNMFEKLDNAAELRIHAQVTHVLNTLLPDQVDSIAITLYPGSAHIIVVFGLDAELVIKGDIRFESQTAEFKAI
What are the official names of this protein?
Uncharacterized 10.1 kDa protein in cd-pseT intergenic region.
Protein: PCNA_THEGJ
Sequence: MPFEIVFDGAKEFADLIATASNLIDEAAFKITEEGVSMRAMDPSRVVLIDLNLPESIFSKYEVEEPETIGINMDHFKKILKRGKSKDTLILRKGDENFLEITFEGTAKRTFRLPLIDVEELELELPELPFTAKVVLLGEVLKEAIKDASLVSDSLKFIAKEDEFTMKAEGETNEVEIKLTLEDEGLLDLEVEEETRSAYGISYLADMVKGIGKADEVTLRFGTEMPLQMDYFIRDEGKLTFLLAPRVEE
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
What are the official names of this protein?
DNA polymerase sliding clamp, Proliferating cell nuclear antigen homolog, PCNA.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: RECO_HUMAN
Sequence: MGNSKSGALSKEILEELQLNTKFSEEELCSWYQSFLKDCPTGRITQQQFQSIYAKFFPDTDPKAYAQHVFRSFDSNLDGTLDFKEYVIALHMTTAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIVMAIFKMITPEDVKLLPDDENTPEKRAEKIWKYFGKNDDDKLTEKEFIEGTLANKEILRLIQFEPQKVKEKMKNA
What is the function of this protein?
Acts as a calcium sensor and regulates phototransduction of cone and rod photoreceptor cells (By similarity).  Modulates light sensitivity of cone photoreceptor in dark and dim conditions (By similarity).  In response to high Ca(2+) levels induced by low light levels, prolongs RHO/rhodopsin activation in rod photoreceptor cells by binding to and inhibiting GRK1-mediated phosphorylation of RHO/rhodopsin (By similarity).  Plays a role in scotopic vision/enhances vision in dim light by enhancing signal transfer between rod photoreceptors and rod bipolar cells (By similarity).  Improves rod photoreceptor sensitivity in dim light and mediates response of rod photoreceptors to facilitate detection of change and motion in bright light (By similarity).
What are the official names of this protein?
Recoverin, Cancer-associated retinopathy protein, Protein CAR.
What is the protein family that this protein belongs to?
Belongs to the recoverin family.
What are the subcellular locations of this protein?
Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment. Photoreceptor outer segment membrane; Lipid-anchor; Cytoplasmic side. Perikaryon. Note=Primarily expressed in the inner segments of light-adapted rod photoreceptors, approximately 10% of which translocates from photoreceptor outer segments upon light stimulation (By similarity). Targeting of myristoylated protein to rod photoreceptor outer segments is calcium dependent (By similarity).
Protein: LOX1_TANCI
Sequence: MALAKQIMGASLMDQKTSVFGSNLCLNHVLVNKHRLRLRKTRKNGSMVVAAISEDLVKLXRVEKEKPVTFKVRAVLTVRNKNKEDFFKDTIFRKIDAITDQIGWNVVIQLFSNDIDPRTRAAKKSNEAVLKDWSKKSNVKTERVNYTADIMVDSDFGIPGAITISNKHQKEFFLETITIEGFACGPVHFPCNSWVQSTKDLPNPRIFFTNQPYLPDETPVGLKSLRYQELKDLRGDGTGVRKLSDRIYDYDVYNDLGNPDRGNDFVRPTLGGEKIPYPRRCRTGRVPSDTDITAESRVEKPFPLYVPRDEQFEESKANAFSTGRLRAVLHNLLPSMVTSISKKNDFKGFSQIDSLYSEGVFLKLGLQDDLLKKLPLPNLVTRLHESSQGGGLLKYDTPKILSKDKFAWLRDDEFARQTIAGVNPVSIEKLKVFPPVSQLDPEKHGPQESALREEHIVGFLDGRTVKQAIEEDKLFIIDYHDIYLPFLDRINALDGRKAYATRTIFYLNPSGTLKPVAIELSLPQALPGSESKRVLTPPSDATSNWMWQLAKAHXCSNDAGAHQLVHHFLRTHAAIEPFILAAHRQLSAMHPIYKLLDPHMRYTLEINQLARQNLINADGVIEACFTPGRYGMEISASAYKNWRFDLEGLPADLIRRGMAVPDPSKPHGLKLVMEDYPYASDGLMIWEAIQNWVKTYVNHYYPDSAQVCNDRELQAWYAESINVGHADLRHKDWWPTLAGADDLTSVLTTIIWLASAQHAALNFGQYPYGGYIPNRPPLMRRLLPDVNDPEYLSFHDDPQKYFLSALPSLLQSTKYMAVVDTLSTHSPDEEYIGERQQTDTWSGDAEIVEAFYAFSAEIQRIEKEIEKRNSDTSLKNRCGAGVLPYELLAPSSGPGATCRGVPNSISI
What is the function of this protein?
Component of the monoterpenoid pyrethrins biosynthesis; pyrethrins are widely used plant-derived pesticide (PubMed:30468448).  Plant lipoxygenases may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.  Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure (By similarity).  Mediates the peroxidation of linolenic acid leading to the production of 13-hydroperoxylinolenic acid (PubMed:23893337).
What are the official names of this protein?
Lipoxygenase 1, chloroplastic, TcLOX1, 13-hydroperoxylinolenic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the lipoxygenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: 3NO28_NAJNA
Sequence: LTCLNCPEVYCRRFQKCRNGEKICFKKFDQRNLLGKRYEIGCAATCPEAKPREIVQCCSTDKCNR
What is the function of this protein?
Binds with low affinity to muscular (alpha-1-beta-1-delta-epsilon/CHRNA1-CHRNB1-CHRND-CHRNE) and very low affinity to neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR).
What are the official names of this protein?
Weak neurotoxin 8.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Ancestral subfamily. Orphan group II sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RSMG_BURP0
Sequence: MTVQQRRRPPIASRETLQALLSEGAQALGVALSDAQRSALLDYVALLAKWNAVYNLTAIRDPRQMLIQHILDSLSIVPHLGAHGAAAAALDVGSGGGLPGVVLAIALPGWRVTLNDIVHKKSAFQNQAKAELKLGNLSVVTGRVETLRPGADVPAKFDVIVSRAFADLADFVTLARHLVAPGGSIWAMKGVRPDEEIGRLPDGARVKQMIRLTVPSLDAERHLIEVELDEAI
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBX17_HUMAN
Sequence: MGARLSRRRLPADPSLALDALPPELLVQVLSHVPPRSLVTRCRPVCRAWRDIVDGPTVWLLQLARDRSAEGRALYAVAQRCLPSNEDKEEFPLCALARYCLRAPFGRNLIFNSCGEQGFRGWEVEHGGNGWAIEKNLTPVPGAPSQTCFVTSFEWCSKRQLVDLVMEGVWQELLDSAQIEICVADWWGARENCGCVYQLRVRLLDVYEKEVVKFSASPDPVLQWTERGCRQVSHVFTNFGKGIRYVSFEQYGRDVSSWVGHYGALVTHSSVRVRIRLS
What is the function of this protein?
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.  Able to recognize and bind denatured glycoproteins, which are modified with complex-type oligosaccharides.  Also recognizes sulfated glycans.  Does not bind high-mannose glycoproteins.
What are the official names of this protein?
F-box only protein 17, F-box only protein 26.
Protein: EYA3_HUMAN
Sequence: MEEEQDLPEQPVKKAKMQESGEQTISQVSNPDVSDQKPETSSLASNLPMSEEIMTCTDYIPRSSNDYTSQMYSAKPYAHILSVPVSETAYPGQTQYQTLQQTQPYAVYPQATQTYGLPPFGALWPGMKPESGLIQTPSPSQHSVLTCTTGLTTSQPSPAHYSYPIQASSTNASLISTSSTIANIPAAAVASISNQDYPTYTILGQNQYQACYPSSSFGVTGQTNSDAESTTLAATTYQSEKPSVMAPAPAAQRLSSGDPSTSPSLSQTTPSKDTDDQSRKNMTSKNRGKRKADATSSQDSELERVFLWDLDETIIIFHSLLTGSYAQKYGKDPTVVIGSGLTMEEMIFEVADTHLFFNDLEECDQVHVEDVASDDNGQDLSNYSFSTDGFSGSGGSGSHGSSVGVQGGVDWMRKLAFRYRKVREIYDKHKSNVGGLLSPQRKEALQRLRAEIEVLTDSWLGTALKSLLLIQSRKNCVNVLITTTQLVPALAKVLLYGLGEIFPIENIYSATKIGKESCFERIVSRFGKKVTYVVIGDGRDEEIAAKQHNMPFWRITNHGDLVSLHQALELDFL
What is the function of this protein?
Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph).  'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress.  Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1 (PubMed:19234442, PubMed:19351884).  Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis.  Coactivates SIX1, and seems to coactivate SIX2, SIX4 and SIX5.  The repression of precursor cell proliferation in myoblasts by SIX1 is switched to activation through recruitment of EYA3 to the SIX1-DACH1 complex and seems to be dependent on EYA3 phosphatase activity (By similarity).  May be involved in development of the eye.
What are the official names of this protein?
Eyes absent homolog 3.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. EYA family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs) (PubMed:19234442). With decreasing efficiency, translocalized to the nucleus by SIX2 and SIX5, and SIX4, respectively (By similarity).
Protein: Y1868_SULIY
Sequence: MSAPTSYDDEELEELLRRKAAQEQKRLEEERKRKAELESQKESILRVILTPEARQRLTNIKLVKPEFAESLENQLIALAQSGRIKVPITDEELKQILEQISEQNRRDFKIQIRERGWK
What are the official names of this protein?
DNA-binding protein YG5714_1868.
What is the protein family that this protein belongs to?
Belongs to the PDCD5 family.
Protein: GLMS_BUCAP
Sequence: MCGIVAAVTQRNIIDFLLEGIKKLEYRGYDSSGLAIINKNQNIVRIRCVGRVNKLLKKVKKKKLFSNIGLAHTRWATHGQVSEKNTHPHISSHIAVVHNGVIENNTKLRHFLEKKGYIFYSDTDTEVIAHLLHWEQTKTGESLVEVIQRSKMKLNGNYSMVVMDAYNSSRLIAVRSGSPLVIGLGIKENFIASDQIALLNITKRFIYLEEGDTAIVETKKINIFNKNNLIIKRKEITSNVKYKSINKGKYKHYMEKEIYEQPISIQNTLNNRIKKDTINFSELGDREKKFFLNAEHIQIVACGTSYHAAMVSRYWFESLANIPCDVEIASEFSSRKLAVRKKSVFITLSQSGETADTLAALRISKKLGYLGSLTICNMKGSSLVQESDCYLLTKAGIEIGVASTKSFTTQLTVLLMLIAKITKLKKQKNNIEKKIAQILSLLPSKVEAILKKNTLIKTLANQLCNKKNILFLGRGDQYPIAMEGALKLKEISYIHAEAYPSGELKHGPLALIDKNIPVIITAPKNSLLEKTKKNIKEICARGGIIYVFSDQEIDLEKNMTIIKIPYVEEIIAPILYIIPLQLLAYYIALSKGKNIDQPRHLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.