PharMolix/UniProtQA huggingface dataset:
Protein: KT33A_HUMAN
Sequence: MSYSCGLPSLSCRTSCSSRPCVPPSCHGCTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPSNPCATTNACDKSTGPCISNPCGLRARCGPCNTFGY
What are the official names of this protein?
Keratin, type I cuticular Ha3-I, Hair keratin, type I Ha3-I, Keratin-33A, K33A.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: MSRQ_ECOUT
Sequence: MRLTAKQVTWLKVCLHLAGLLPFLWLAWAINHGGLGADPVKDIQHFTGRTALKFLLATLLITPLARYAKQPLLIRTRRLLGLWCFAWATLHLTSYALLELGVNNLALLGKELITRPYLTLGIISWVILLALAFTSTQAMQRKLGKHWQQLHNFVYLVAILAPIHYLWSVKIISPQPLIYAGLAVLLLALRYKKLLSLFNQLRKQVHNKLSL
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYH_SHELP
Sequence: MAKQIQAIRGMNDILPTQSPLWQKLEAVLRDTVAAYGYSEIRTPIVESTDLFKRSIGEVTDIVEKEMYTFADRNGDLLTLRPEGTASTVRAGNEHGLLYNQEQRLWYMGPMFRHERPQKGRYRQFNQFGVEVYGIASADIDAEVLMMSHRLWQKLGISEHVKLELNTLGDAQERAAYRDALVEFLEQHEEKLDEDSQRRMYSNPLRVLDSKNPDVQALLGDAPALMDYLGEESRGHFAHLCELLEAVGIQYEINPRLVRGLDYYNRTVFEWVTDSLGAQGTVLAGGRYDGLVGQLGGKDTPAVGFAMGLERIVLMLETLALTDDVSGPVDVYVTAMGDDCRVAAIKVAQQLREVDGLKVMSHCGGGNFKKQMKRADKSGAKLAIVIGETELANGQVALKYLREEKEQELVAQDSLAAYVAELI
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTMB1_METAC
Sequence: MTFRKSFDCYDFYDRAKVGEKCTQDDWDLMKIPMKAMELKQKYGLDFKGEFVPTDRDMMEKLFQAGFEMLLECGIYCTDTHRIVKYTEDEIWDAINNVQKEFTLGTGRDAVNVRKRSVGDKRKPIVQGGPTGSPISEDVFMPVHMSYALEKEVDTIVDGVMTSVRGKPPVPKSPYEVLAAKTEARLIKQACAMAGRPGMGIOGPETSLSAQGNISSDCVGGQISSDSHEVSQLNELKIDLDAIAVIAHYKGNSDIIMDEQMPIFGGYAGGIEETTIVDVATHINAFVMSSASWHLDGPVHIRWGSTNTRETLTIAGWACATISEFTDILSGNQYYPCAGPCTEMCLLEASAQSITDTASGREILSGVASAKGVVTDKTTGMEARMMGEVARATAGVEISEINKILDKLVALYEKNYANAPAGKTFQECYDVKTVTPTEEYMHVYDGARKKLEDLGLVF
What is the function of this protein?
Catalyzes the transfer of the methyl group from monomethylamine to the corrinoid cofactor of MtmC.
What are the official names of this protein?
Monomethylamine methyltransferase MtmB1, MMA methyltransferase 1, MMAMT 1.
What is the protein family that this protein belongs to?
Belongs to the monomethylamine methyltransferase family.
Protein: MQO_BURL3
Sequence: MKKGSAVIKTLRVILSALALCVATSSAHAADTKKVDVLLVGGGIMSSTLGVWLHELQPDWSMTMVERLDGVALESSNGWNNAGTGHSALAELNYTPEKADGKIDISKAIEINESFQISRQFWAWQVKQGVLKNPHSFINSTPHMSFVWGDDNVRFLKKRYEALQASPLFRGMQYSEDYDQIKQWVPLMMEGRDPKQKVAATWTPIGTDVNFGEITRQFVGYLKTQPNFTLSLSSEVREISRNADGTWHVSWVKLHSDEPAQSVDAKFVFIGAGGGALHLLQASGVPEAKDYGAFPVGGSFLVTENPEVVKQHLAKAYGKASVGSPPMSVPHLDTRIIDGKKIILFGPFATFSTKFLKNGSYFDLLKSTNTHNVAPMMRVGVDEFPLVQYLAGQLMLSDDDRFNALKEYFPNAKKEDWRLWQAGQRVQIIKRDPVKGGVLKLGTEIVASQDGSIAGLLGASPGASTAAPIMLNLMKKVFKDKVATPEWQQKIRQIVPSYGTKLNDSPAKVVEEWTYTSDVLQLSPPPKIDVNTPSQATGTAPARPAKASADMAL
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: PEBB_SYNS3
Sequence: MTIQRLKSTDPVSIEGWSWQPFLEDAIKSLGGLNFEPYPVPDRFLQREDQTGSKSKPISVTTATWACKTEKFRQVRAACVSAGSAASVLNFVINPNSTYDLPFFGGDLVTLPSGHLLALDLQPAIKTDEVHTTHVWDQLIPIFERWRDQLPYGGPIPEEAQPFFSPGFLWTRLPLGEEGDDLIQSVVRPAFNEYLELYLQLAASAERVNAERSDFLLQGQRKYTDYRAEKDPARGMLTRFHGSEWTEAYIHTVLFDL
What is the function of this protein?
Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin.
What are the official names of this protein?
Phycoerythrobilin:ferredoxin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the HY2 family.
Protein: RL5_STRZJ
Sequence: MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEAVSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLDKLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTTANTDEESRALLTGLGMPFAK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: IF2P_METBF
Sequence: MADKKNLRTPIVCVMGHVDHGKTTLLDKIRGTAIVSGEAGAITQHIGATEVPIDVIINKLGDPRLRDRFIVPGLLFIDTPGHHAFTTLRSRGGALADLAIVVVDINEGFKPQTYESLQILKRFKTPFVVVANKIDRIGGWVSQKDLPFAVTFKKQSEDVQARLETKLYEVIGELYNQGFAAERYDRVTNFQKTLGVVPVSAMTGEGIPDVLMVLLGLAQKFLEANLHYSAKGPGVGTVLEVKEEKGLGATLDVILYDGTLKKGDTVVIGSLGKPIQTKVRALLKPRELSEMRYESKFKQVNKVTAAVGVKISAPGLEGALAGSPIRVANEDTLDEIVDQIKSEIDEVRIDTGAVGIMIKADTLGSLEALVHEFQKDEVSIRKAEVGDISHRDAIEASTVEDPLYSVIIGFNVKVHPDARDFLQESTVKVFTSDVIYRLVEDYQKYVKEQQEQAEKRIFETIIRPGKFKILPGCIFRQSKPAVVGIRVLGGVVRTNADVMLENGNVVGKIKGLQIEGENIPSAGVGKEVAMAIEGATVGRQIKEEDVLYVNVPERHAKVLEHEIYDSLSTDEKETLDIFLSLKRKDNPFWAK
What is the function of this protein?
Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes.  Seems to function along with eIF-2.
What are the official names of this protein?
Probable translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
Protein: XPT_BACFN
Sequence: MQLLKKRILQDGKCYEGGILKVDSFINHQMDPVLMKSIGVEFVRLFAGTNVNKIMTIEASGIAPAIMTGYLMDLPVVFAKKKSPRTIQNALSTTVHSFTKDRDYEVVISSDFLTPKDNVLFVDDFLAYGNAALGVIDLIKQSGANLVGMGFIIEKAFQNGRKTLEERGVRVESLAIIEDLSNCRITIKD
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBID_PSESM
Sequence: MKFKDLRDFVQQLEQRGELKRIQMPISPVLEMTEICDRTLRAKGPALLFENPVGFDIPVLGNLFGTPERVAMGMGAEAVTELREIGKLLAFLKEPEPPKGLKDAWSKLPIFRKVIAMAPKVVKDAPCQEIVIEGDDVDLGMLPVQTCWPGDVAPLITWGLTVTKGPNKERQNLGIYRQQVIGRNKIIMRWLSHRGGALDFRDWCVKHPGEPYPVAVALGADPATILGAVTPVPDSLSEYAFAGLLRGSRTELIKCRGSNLQVPASAEIVLEGVIHPGEMANEGPYGDHTGYYNEVDSFPVLTVERITHRIKPIYHSTYTGRPPDEPAILGVALNEVFVPILQKQFPEIVDFYLPPEGCSYRMAVVTIKKQYPGHAKRVMLGVWSFLRQFMYTKFVIVTDDDINARDWNDVIWAITTRMDPKRDTVMIDNTPIDYLDFASPVSGLGSKMGLDATNKWPGETTREWGRAIVKDEATTRRVDEIWTQLGID
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ACDH_BACC3
Sequence: MQKVKAAIIGSGNIGTDLMYKLRKSEVIDLNAMIGIDVESDGLKRAKEAGYEVFDNGIQAIIDNPSLADIVFDATSAKAHRYHAKTLEELEKIVIDLTPAAYGPFVCPAIRNNNFLDKQNVNMITCGGQATIPIVHAINGVANVTYAEIVATISSLSAGPGTRANIDEFTITTKRGIEEVGGADKGKAIIILNPAEPPILMRDTIYCEVKDMDEVSIYEAIHKMVERVRTYVPGYSLKQEPMFDGNRVTVFLEVEGAGDYFPPYAGNLDIMTAAALKVGEEFATQIISEKKRGVMNEAK
What are the official names of this protein?
Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: HSLV_JANMA
Sequence: MEQFHGTTILSVRRGNIVALGGDGQVTLGNIVMKGTARKVRKVYNGKVLVGFAGGTADAFTLLERFESKLEKHQGHLMRASVELAKDWRTDRMLRRLEAMLLVADKETTLIITGNGDVLEPNDGIGAIGSGGTYAQSAAKALQENTDLSPEDIVKKSLTIAGELCIYTNLSHIIETLD
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3H_XENTR
Sequence: MAARTRETGNTATVAETAVKQVQIDGMVVLKIIKHYQEEGHGSEVVQGVLLGLVVDDRLEITNCFPFPQHTEDDVDFDEVQYQMEMMRSLRHVNIDHLHVGWYQSTFYGTFVSRALLDSQFSYQHAIEESVVLIYDPIKTGQGSLSLKAYRLTPKLMEVCKEKDFSAEGLKKANIAFEDMFEEVPIIIKNSHLINVLAWELDKKAPVTEKHELLNLSSSNHLEKSLQLLMDRVDELSQDIVKYNTYLRNISKQQQQKHQYTQRRQQENLQRQSRGETSLPEEDVNKLFKPPVPPSRMDSLLIAGQINTYIQHIKEFTSQNLGKLFMAEAMQDPTI
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit H, eIF3h, Eukaryotic translation initiation factor 3 subunit 3, eIF-3-gamma, eIF3 p40 subunit.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A1OB3_LOXVA
Sequence: WIMGHMVNNIKQIDEFVNLGSNAIETDVSFDKKANPEYTYHGTPCDCGRDCLRWEYFNDFVKALRTATTPGNSKYDKLFLVVFDLKTSSLYDYQASEAGTKLAKNLLQHYWNNGNNGGRAYIILSIPNLKHYKLITGFQQTLKDEGHAELLDKVGYDFSGNDDIGDVQKTYEKAGVTGHVWQSDGITNCLLRSFTRINAAVANRDSANGIINKVYYWTVDKRQTTRDTLDANVDGIMTNYPDITVEILNEDAYKTKFRIATYEDNPWETFKE
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LvSicTox-alphaIC1biii, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RSMB_XYLFA
Sequence: MVAARVLALVVDQGRSLKTELAAALPTLEDVRDRALVEAICFAVLRRRPVYEAALTQWLARPLGRGDAQLRGLLMVGFAQLDVLKVPPYAALSATVDACRVLGWPHRASFVNAVLRRAQRERLPVVSSDAAWPRWLAERIRADWGELAEAIFDASLKPAPMWLRVNLRYGDRHTYVQRLQAAGLEAVPSGLVPEALALDCSMPVLQLPGFQAGEVSVQDLSAQQVAALLSPAPHARVLDACAAPGGKAAHLLERAPTLCLTALDVDMQRLRRVAETCDRIHVKARLCVADATDLAAWWDGEAFDAVLLDAPCSATGVVRRQPDVLLHRRAEDLLPLLNIQSRLLDACWRTLRPGGVLVYVTCSVLRAENQTQLEAFLARTVDACAEDPGDAYGQPAGLGRQRLPGEQGGDGFFYARLIKEI
What is the function of this protein?
Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase B, 16S rRNA m5C967 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmB.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTTG_HUMAN
Sequence: MAPGVARGPTPYWRLRLGGAALLLLLIPVAAAQEPPGAACSQNTNKTCEECLKNVSCLWCNTNKACLDYPVTSVLPPASLCKLSSARWGVCWVNFEALIITMSVVGGTLLLGIAICCCCCCRRKRSRKPDRSEEKAMREREERRIRQEERRAEMKTRHDEIRKKYGLFKEENPYARFENN
What is the function of this protein?
May facilitate PTTG1 nuclear translocation.
What are the official names of this protein?
Pituitary tumor-transforming gene 1 protein-interacting protein, Pituitary tumor-transforming gene protein-binding factor, PBF, PTTG-binding factor.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Cytoplasm. Nucleus. Note=According to PubMed:10781616, it is found in the cytoplasm and the nucleus.
Protein: NEP_HUMAN
Sequence: MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW
What is the function of this protein?
Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:6349683, PubMed:6208535, PubMed:15283675, PubMed:8168535).  Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:6349683, PubMed:17101991).  Catalyzes cleavage of bradykinin, substance P and neurotensin peptides (PubMed:6208535).  Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 (PubMed:6349683, PubMed:15283675).  Involved in the degradation of atrial natriuretic factor (ANF) and brain natriuretic factor (BNP(1-32)) (PubMed:2531377, PubMed:2972276, PubMed:16254193).  Displays UV-inducible elastase activity toward skin preelastic and elastic fibers (PubMed:20876573).
What are the official names of this protein?
Neprilysin, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, Enkephalinase, Neutral endopeptidase 24.11, NEP, Neutral endopeptidase, Skin fibroblast elastase, SFE.
What is the protein family that this protein belongs to?
Belongs to the peptidase M13 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: SCXNF_MESEU
Sequence: MMKIIIFLIVSSLVLIGVKTDNGYLLDKYTGCKVWCVINNESCNSECKIRRGNYGYCYFWKLACYCEGAPKSELWHYETNKCNGRM
What is the function of this protein?
Inhibits sodium channels (Nav).  Has antimicrobial activity.
What are the official names of this protein?
Sodium channel neurotoxin MeuNaTxalpha-15, Sodium channel neurotoxin MeuNaTxalpha-6.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family.
What are the subcellular locations of this protein?
Secreted.
Protein: TDH_PARXL
Sequence: MKALAKLERAPGLTLTDVKKPEVGHNDVMIRITRTAICGTDIHIWKWDDWAQKTIPVPMHVGHEYVGEIVEMGQEVRGFAIGDRVSGEGHITCGFCRNCRAGRRHLCRNTVGVGVNREGAFAEYLVIPAFNAFKIPPEISDDLAAIFDPFGNATHTALSFNLVGEDVLITGAGPIGIMAVAIAKHVGARNVVITDVNDYRLELARKMGATRAVNVSRESLRDVMADLHMAEGFDVGLEMSGVPSAFTGMLEAMNHGGKIALLGIPPAQTAIDWTQVIFKGLEIKGIYGREMFETWYKMVAMLQSGLDLSPILTHHFKVDDYREAFATMLSGESGKVILDWTAA
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_FRATF
Sequence: MFKKTKITILGATGSIGDSTLAVIRETNDFEVFALTAFSNVEKLAELCQEFKPKFAVVPDLSKKQKLQSLVTDVEVLVGESGLEKVSSLAEIDIVMSAIVGIAGLKPTFAAAKAGKKILLANKESLVTAGHLLIDEVVKNNAQLIPVDSEHNAIFQCIDNHDKKCLPEIDKIILTASGGPFRDKQLHELTDVTPEQACNHPNWQMGRKISVDSSTMVNKALEVIEAYWLFSVSADKIGVLIHPQSVTHSIVRYVDGSYIAQLGVPDMKTPIANAMYYPKRGSVNVESLDFTKYQLTFREACFERFEALKIVFNNLQNKNYAANIVFNAANEELVAAFLNKKIKYLEIIEVNKKVTKELNFENPKNIEEVFEIDRKTREYVDSVLG
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: HIBC2_ARATH
Sequence: MASHSQVLVEEKSSVRILTFNRPKQLNALSFHMVSRLLQLFLAYEEDPSVKLVVLKGQGRAFSAGGDIPPIVRDILQGKLIRGAHYFKVGYTLNYVLSTYRKPQVSILNGIVMGGGAGLSTNGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSISLTALEAELYKVGSSNQTFISTILDAYAEYPHLNQHSSYHRLDVIDRCFSKRTVEEIFSALEREVTQKPNDWLLATIQALEKASPSCLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGDISKDFVEGCRAVLIDKDRNPKWQPRRLEDVTDSMVDQYFERVEDEEGWEDLKFPPRNNLPALAIAAKL
What is the function of this protein?
Involved in valine catabolism.
What are the official names of this protein?
Probable 3-hydroxyisobutyryl-CoA hydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: LSHB_PANTR
Sequence: MEMLQGLLLLLLLSMGGAWASREPLRPWCHPINATLAVEKEGCPVCITVNTTICAGYCPTMMRVLQAVLPPLPQVVCTYRDVRFESIRLPGCPRGVDPVVSFPVALSCRCGPCRRSTSDCGGPKDHPLTCDHPQLSGLLFL
What is the function of this protein?
Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
What are the official names of this protein?
Lutropin subunit beta, Lutropin beta chain, Luteinizing hormone subunit beta, LH-B, LSH-B, LSH-beta.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: CX6B1_MACFA
Sequence: MAEEDIETKIKNYKTAPFDSRFPNQNQTRNCWQNYLDFHRCQKAMTTKGGNVSVCEWYQRVYQSLCPTSWVTDWDEQRAEGTFPGKI
What is the function of this protein?
Connects the two COX monomers into the physiological dimeric form.
What are the official names of this protein?
Cytochrome c oxidase subunit 6B1, Cytochrome c oxidase subunit VIb isoform 1, COX VIb-1.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space.
Protein: FMT_BORDL
Sequence: MRIFFASSDVIALEVLKKISDQYDVVGVLTAPDKPSGRGLSLKVNDIKREALSRKITVLQPVVLDADVINLVKSLEPELMLVFSYGKIFKQEFLDIFPVGCINIHPSLLPKYRGPSPIQTAILNGDSISGITVQKMTLEMDSGNILAQSQFEIKSFNTSVDIFEYVSLNSFDLVIEALNKLLKGDIGIVQDKNNATYCSFLGKEHRTIDFKLSAFDIKNKINAYNPWPLARARLDNNEIIFHRADFISTNDYDDQVIGKIIAFDPSKGLLVKTGDGILVVLELQRIGKKVLDCVSFYHGNRDLIGKVFS
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: COXX_RICRO
Sequence: MSSLVRPINLGKINNSQSTVKDYILLMKPRVMSLVIFTGFVGMWLAPYSVHPFIAGIAVVCIALGAGSAGAINMWYDRDIDSLMKRTQKRPIVRGVIESDEALSFGLITGFFAVFFMALCVNLLASFLLLFTIFYYICIYTIWLKRRSIQNIVIGGVSGALPPVIGYAAVSNTISLESIILFLIIFIWTPPHSWALALFCNDDYKNCKVPMMPAVKGTVYTKKQILIYSILLFIVSLMPFFIGMNNFIYLIISGILGVVFLYYAGSLFYDTPDNKQAKRFFAYSIFYLFFIFLLLYSTNTISTIS
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FMT_RHOBA
Sequence: MEPRRMADSLRYVLMGTGPFAVPSFEAIRQQMDSTGDQIARVFVRPLPPVKSRGGPPPQPVREWAESHGLPVDAPASINDPETIASLTELNADLLVVCDYGQILKPDALQSARLGGINLHGSLLPAYRGAAPVQRALLSGDRETGVSVIHMTPRLDGGPIVASRTTPIRDDETSGELEVRLSEIGVDATREAIGLLRTIESLDSHGPLGEPQDPAKVSKAPRLSKAEAQIDWSATGREIDCLVRGMQPWPVAFTHTVVNENKPPLRVAIRGVRTETYAADASNIGRVMEHEGLAIGCGDGQVVIERLQPAGKKEMSGLDFKRGHRLTAGQQLIAP
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: EFM7_KLULA
Sequence: MSDIESLNGGDLFAEPSDFYKPPPEPHFATYTRDDVPESSTSQQKDIKLRLVGSSPLWGHLLWNAGIYTAKHMDSHPEEVQDKLVLELGAAGALPTIIAGLLGARKVVSTDYPDADLISNIQYNVDHNIYGGEELFKDEEKRSKQMANRKVVVEGYIWGNDYEPILKHLPQDQQKFDLIILSDLVFNHTEHAKLFKTTKDLLRENGKALVVFSPHRPWLLENDLAFFKDCEEFGLKSDLIELTHWKPMFDEDEETVEIRSSIYAYYLSHI
What is the function of this protein?
S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.
What are the official names of this protein?
Protein N-terminal and lysine N-methyltransferase EFM7, Elongation factor methyltransferase 7.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_FRATN
Sequence: MENKKVIVGISGGVDSSVSALLLKQQGYDVTGVFMKNWEEDDTDEFCSAEQDIADAQAVCDSIGIPFKKINFAAEYWDNVFEHFLIEYKAGRTPNPDILCNKEIKFKAFLSYVHLLGGDYIATGHYARTRVLEDGSVQLVKGLDDNKDQTYFLYTLGQEQLRQTIFPIGNIEKSKVREIAKENNLVTFDKKDSTGICFIGERKFKEFLSKFLPAQKGEIHDENGIKIGMHDGLMYYTIGQRQGLGIGGVKDRPEVPWFAAKKDLENNVLIAVQGHDHPLLFKQSLQAIELSWVAGMAPADKFRCAAKVRYRQKDQSCEVEVNQDGSVNVTFDQPQRAITPGQSVVFYIDDVCLGGGVII
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.