PharMolix/UniProtQA huggingface dataset:
Protein: WSPC_PSEAE
Sequence: MNDRFERLLKSRIGLDASSVGSAVIERAVRQRMSGLALHDEDEYWMRLNGSPGEVQALIEAVVVPETWFFRYPESFTTLARLAFERLPSLGGGRALRILSLPCSTGEEPYSIVMALLDAGLSEYLFEVDALDVSARVIERASLGVYGRNSFRGDELGFRDRHFSEVAEGYQLAEQVRRKVRFRCGNLLDPGLLAGEAPYDFVFCRNLLIYFDRPTQSEVVEVLKRLLRPDGAMFIGPAEASLLSQHGMQPIGVPLSFVFRRTSEAPRGARPKAVSDGARPVVAAAVERASIRPSPPPPAKPRQRLSSLVPPASGQPLASPVGEFDEIARLADAGQHREARAACERQLAARGPSATVFYWLGLLSDVAGQEQEAQDFYRKALYLEPQHAEALAHLAALLAARGDHAGARRLQQRAARGVNKDG
What is the function of this protein?
Involved in biofilm formation.
What are the official names of this protein?
Probable biofilm formation methyltransferase WspC.
Protein: DAPD_JANMA
Sequence: MTQQLEQIIDQAWENRADFSPKNAPADVRNAVAQVIAQLNEGTLRVAQKDSGAWVVNQWVKKAVLLSFRLEDNITMPSGDHMQFYDKVPTKFANYTAEDFAKGGFRVVPPAVARHGSFIGKNVVMMPSFVNIGAYVDEGSMVDAWATVGSCAQIGKNVHLSGGVGIGGVLEPMQANPTIIEDNCFIGARSEIVEGVIVEENSVISMGVYIGQSTKIYDRATGEVTYGRIPAGSVVVSGNLPSADGKYSLYCAVIVKRVDAKTRAKTGINELLRD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGS18_MOUSE
Sequence: MDMSLVFFSQLNMCESKEKTFFKLMHGSGKEETSIEAKIRAKEKRNRLSLLLQRPDFHGETQASRSALLAKETRVSPEEAVKWAESFDKLLSHRDGVDAFTRFLKTEFSEENIEFWVACEDFKKCKEPQQIILKAKAIYEKFIQNDAPKEVNIDFHTKEVIAKSIAQPTLHSFDTAQSRVYQLMEHDSYKRFLKSETYLHLIEGRPQRPTNLRRRSRSFTYNDFQDVKSDVAIWL
What is the function of this protein?
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.  Binds to G(i) alpha-1, G(i) alpha-2, G(i) alpha-3 and G(q) alpha.
What are the official names of this protein?
Regulator of G-protein signaling 18, RGS18.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CA14_CONLI
Sequence: MGMRMMFTMLLLVVLATTVVSFTLDHAFDGRNTAANNKATDLMALPVRGCCSDPPCRHKHQDLCG
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them (By similarity).  At high doses (10 uM), the synthetic non-amidated toxin (residues 49-65) completely inhibits frog sciatic nerve-gastrocnemius muscle contractility (PubMed:33610632).  It also inhibit the cholinergic miniature excitatory postsynaptic currents (mEPSCs) frequency and amplitude of projection neurons in insects (D. melanogaster) (PubMed:33610632).  In vivo, the toxin (100 ug/kg) shows good analgesic effects in mouse hot plate model and formalin test (PubMed:33610632).
What are the official names of this protein?
Alpha-conotoxin-like Lv1.4, Conotoxin Lv1d.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DNAJ_RHOS7
Sequence: MSTTKRCYYETLEVERNADDSTLKSAFRKLAMKWHPDRNPGDPQCEIKFKEINEAYEVLKDGDKRAAYDRYGHAAFEQGGFGGGAGFGAGFASSFSDIFEDLFGMAAQRGRGTGRERGADLRYNMEITLEDAFKGKTAQIEIPVSVTCEACSGTGAKAGTKPKTCSTCGGAGRVRQAQGFFTLERTCPSCQGRGQTIEDPCPSCTGSGRVTKERTLSVNIPQGVEDGTRIRLAGEGEAGLRGGPPGDLYIFLSLANHAIFQRDGADLHCRVPISMVTAALGGEFEVPTIDRGKTKVKVPSGTQTGRRFRIAGKGMPVLRSRQVGDMYVQVVVETPQNLTKKQQELLAEFEKLSSGETQPEAVGFFSKVKEFFGSRASAP
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAC1D_MESAU
Sequence: MMMMMMKKMQHQRQQQEDHANEANYARGTRPPISGEGPTSQPNSSKQTVLSWQAAIDAARQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKTCFFADSDIVAEEDPAPCAFSGNGRQCAVNGTECRSGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLRENEQLEEDLKGYLDWITQAEDIDPENEEEGGEEGKRNTSMPTSETESVNTENVSGEGETQGSCGSLCQAISKSKLSRRWRRWNRFNRRRCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELELMSPLGVSVFRCVRLLRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKIARKESLENKKNNKPEVNQIANSDNKVTIDDYQEETEDKDPYPPCDVPVGEEEEEEEEEPEVPAGPRPRRISELNMKEKIVPIPEGSAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENAGPVYNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALSEADPTESESLPLPTATPGNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDPDSDYNPGEEYTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGGQCGLCFLSPSRSRS
What is the function of this protein?
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.  The isoform alpha-1D gives rise to L-type calcium currents.  Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group.  They are blocked by dihydropyridines (DHP), phenylalkylamines, and by benzothiazepines.
What are the official names of this protein?
Voltage-dependent L-type calcium channel subunit alpha-1D, Calcium channel, L type, alpha-1 polypeptide isoform 2, Voltage-gated calcium channel subunit alpha Cav1.3.
What is the protein family that this protein belongs to?
Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1D subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y1355_NEIM0
Sequence: MFGKAGLGGLMKQAQQMQENMKKAQAKLAETEIEGEAGNGLVKITMTCAHEVRKIDISPDLIQEAADDKEMLEDLILAALKSARDKAEETANKTMGAFAQGLPPGVGDFFR
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein NMCC_1355.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: MATK_CLELA
Sequence: MEELQGYLKIDRSRERDFLYPLLFQEYIYALAHDHGLNKSILYEPMENLGYDKKYSLIIVKRLITRMYQQKHLIIFTNDSNTNFFFGHNKNLDSQMISEGVAVIVELPFSLRLVSSPESKEIDKSMTTLRSIHSIFPFLEDKLLHLNHVLDILIPYPIHLELLVQTLRSWIQDAPFLHLLRFFLYKYHNWNSLITQKTKMILFFSKENQRFFLFLYNFHVYESESIFVFLRKQSYHLRSTSSRAFLDRTHFYRKIEHFLVDFRNDFHTILWLFKDPFIQYFRFQGKSILSSKGTPLLMKKWKYYLVNLWECHFYFWSQPDRIHINQLSNHFIDFLGYLSSVRPTPSAVRSQMLEKSFIIDIVIKKFDTIVPIIPLIGSLAKAKFCNFSGHPISKPAWADSSDSDIIDRFGRICRNLSHYYSGSSKKKSLYRIKYILRLSCARTLARKHKSTVRSFLKRLGSEFLEEFLMEEEQVLSFILPRISYFSKRLYKERIWYFDIIRINDLTNLS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CAPJ_STAAU
Sequence: MQLLFVHDFPVEKYKDNYYSIGFSHKIWNRYLTIFDKMLINSRVKNVDNGEIINKSNGEKVNFKTIDSYKSPKSLIFKHKKIFEALTISIKKSDGVLIRVPSVLGFIAALICKKINKPYMVEVVGAAFDAYWFHGSIFGKILSLPMEYLQKNAVKNASIAIYVTKKYLSNKYPCNGKEFKGISNVQSVEKFNKNLDIGNKIKIGLIGSTFVDYKGHNVAIKSISNLVNEGYNIELEFVGDGPSKKFMEMAKKYNVENNVIFKGKIYDKTALNNWFRNLDLYIQPSLTEGHCRAIVEAIGNGVPTLASNAGGNSDSVNKEYLFKPKDVVKLTKLINRSILSKQYREENVLENKKNISGYNLENIQIEREKALLNYKKIINDFYLAKGINKNA
What is the function of this protein?
Required for the biosynthesis of type 1 capsular polysaccharide.
What are the official names of this protein?
Protein CapJ.
Protein: MRAZ_SHESW
Sequence: MFRGASAINLDTKGRIAIPVRYREPLQLEHQGRIVITVDIQSACLLLYPIHEWELIEAKLLKLSDTDKTQRSLKRLLLGYAHEVELDGNGRILLPPPLRQYANLDKRIMLVGQLNKFELWDEQAWLQQIDECQETIRSEELANNERLADFSL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL24_AYWBP
Sequence: MRIKVGETVAILAGKDRFVTDESGKKMIKTGKVLKVFAKTQKIIVEGVNIKTKHQPPSQNEEKGAIVKQEAPIHVSNVALVDPQTQTSTKVGIRIQSGKKVRYAKKSNQTLDEKN
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: MURE_LACLM
Sequence: MIKLEQVVEILKKDNNFREISSAGEYYFNWPKEVNFDQLSYDSRKSTKDTLFFAKGLNFKKEYLTDLEAAFYVSEFDYEVALPAIIVTDVKRAMALIAANFYEFPQNKLKTLALTGTKGKTTSAYFAKAILDKMNGGKTALLSTAQTTLDGQNYFKSELTTPESLDLLEMMAKALENGMTHLVMEVSSQAYKTERVYGLTFDVGVFLNISPDHIGPVEHPTLEDYFYCKRQLLKNSRYFVANAEMNHFAIIKEELNERKIPHAFYGADSENKIIESKGLHFVTDGSVSGEFDIRLLGRFNQENALATALATKALGASFENIRQGLASAIVPGRMELLTAKNGAHIYIDYAHNGLSLENLVEVVEDHHAGQLFLVLGSTGNKGESRRKDFGQVIENHPRLNVILTTDDSNRENPKTIADEIASFVSRELDFELDREFAIKKAISKTQNSDDAVIIAGKGADMFQLKDGKREPYIGDSPAAQKYL
What is the function of this protein?
Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramyl-tripeptide synthetase, UDP-MurNAc-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_DINSH
Sequence: MSRPHFQFETDLAARGYLRIAGVDEVGRGPLAGPVMAAAVVLDPGAIPEGLNDSKQVTAKRREALAAQLAQVAQVGVGVAEVAEIDRLNIRRAAHLAMLRALDALPAPPDMALIDGRDRPDDLPCAAHAIIKGDTKSLSIAAASIVAKVARDRVMTALAAEFPGYGWETNAGYPTQAHRAALLDIGVSPHHRRSFRPVHNILYQEK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA_BACAN
Sequence: MERFKKASSIIETLKQQGHEAYFVGGSVRDLIIDRPIGDIDIATSALPEEVMAIFPRHVPVGLEHGTVIVVENGEPYEVTTFRTESEYEDFRRPSSVQFVRSLEEDLKRRDFTMNAIAMTEEGEMVDLFAGQEAIQKREIVTVGNAADRFQEDALRMMRGIRFVSTLGFSLETKTKQAIETYGHLLEHIAIERITVEFEKLLTGTYCVKGLKELVETKLFSHLPYLQMSEERLLKATQYNWDSFETDIEAWAFFLYCIGEEHPSVFLRQWKFSNKKIKDIVAVLLTIRKRKEKDWDTVLLYKTGIHIAEMAERVYEAMIESYDHTSVERVQTLFQALPIKSRQEMDVTGNDLLNWASKKPGPWVAEMIQKIEEAIVQGNVVNEKECIREWLQECNLL
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
Protein: SDHF2_CAEBR
Sequence: MTTLLGPITRRFLSATQIARSLTRAEVPGEQLDAKRARLLYQSKKRGILENDILLGNFAEENLKKMSEPELKAYDKLINGEHMEWDLFYYLSNKKTPPEDVEKCSVYQKVKKFVDEKRVPRS
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 2, mitochondrial, SDH assembly factor 2, SDHAF2.
What is the protein family that this protein belongs to?
Belongs to the SDHAF2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PURQ_CAMJE
Sequence: MKVAIIRFPGTNCEFDTTYAFEKLGVKTQIVWHEEKEFDADLVVLPGGFSYGDYLRCAAIAKLAPAMQGVFNHAKKGGYILGICNGFQILLESGLLKGAMKHNNNLSFISKNQSLRVVSNDNAFLKNFKKDEIINLPIAHGEGNYYADETTLKELQDKDLIILKYEPNPNGSVFDIAGICDENKKIFGLMPHPERACEKVLGNDVGLKMLKGFLLENFINFNF
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_LACLS
Sequence: MVDVNKFESMRIGIASPQKIRYWSFGEVKKPETINYRTQKPEREGLFDERIFGPQKDWECACGKLKGVFYKNQVCELCGVQVTTAKSRRERMGHIELAAPISHIWYFKGIPSRMGLALDMSPRALEEVIYFASYVVIDPKETDLEKKQLLTEREYREQLLKNGFGSFVAKMGAEAIQDLLNDVDIDKEVAELKEELKTVTGQRRVKIIRRLDVLSAFRKSGNALSWMVLNVLPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLMELNAPNIIVQNEKRMLQEAVDTLIDNGRRGRPITGAGNRPLKSLSHMLKGKQGRFRQNLLGKRVDYSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMAQLVKKELAANIRAAKRKVERQDSDVWDVLETVVKEHPVLLNRAPTLHRLGIQAFEPVLIDGKAIRLHPLACEAYNADFDGDQMAIHLPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEKGREGEGMIFATPEEVEIAMRNGYVHLHTRIGIATKSLNKPWTENQQDKILVTTVGKVIFNSIIPEGMPYLNEPTDVNLTTSTDDRFFMDAGQNIKEVLAGIDTVRPFKKGYLGNIIAEVFKRYRTTATSEYLDRLKDLGYYQSTLAGLTVGIADIPVVEDKHEIIDAAHKRVEQITKQFRRGLITDDERYNAVTGVWRDAKESLEKRLIEEQDLTNPIVMMMDSGARGNISNFSQLAGMRGLMAAPNGKIMELPIISNFREGLSVLEMFFSTHGARKGMTDTALKTADSGYLTRRLVDVAQDVIIREDDCGTDRGLVIADIATGKEMVEPLFERLVGRYTRKSVLHPETGEMIIGDDTLISEDIARKIIEAGVKEVTIRSVFTCKTPHGVCKHCYGINLATGDAVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASSSDITQGLPRVQEIFEARNPKGEAIITEVTGTVESIVEDGATRTREITVKGKTDTRSYTVGMADVLMVEEGEFIHRGAPLIQGSIEPKHLLQVRDALSVETYLLGEVQKTYRSQGVEIGDKHIEVMVRQMLRKVRIMDNGSIDVLPGTLMDISDFEALNETALLNGEMPATGRPVLMGITKASLETNSFLSAASFQETTRVLTDAAIRGKEDHLLGLKENVIIGKIIPAGTGMFRYRNIEPLADLTNAPEVKEVETETVEN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: PPM1K_HUMAN
Sequence: MSTAALITLVRSGGNQVRRRVLLSSRLLQDDRRVTPTCHSSTSEPRCSRFDPDGSGSPATWDNFGIWDNRIDEPILLPPSIKYGKPIPKISLENVGCASQIGKRKENEDRFDFAQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMDLLPKEKNLETLLTLAFLEIDKAFSSHARLSADATLLTSGTTATVALLRDGIELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKTSGVIAEPETKRIKLHHADDSFLVLTTDGINFMVNSQEICDFVNQCHDPNEAAHAVTEQAIQYGTEDNSTAVVVPFGAWGKYKNSEINFSFSRSFASSGRWA
What is the function of this protein?
Regulates the mitochondrial permeability transition pore and is essential for cellular survival and development.
What are the official names of this protein?
Protein phosphatase 1K, mitochondrial, PP2C domain-containing protein phosphatase 1K, PP2C-like mitochondrial protein, PP2C-type mitochondrial phosphoprotein phosphatase, PTMP, Protein phosphatase 2C isoform kappa, PP2C-kappa.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RNT_XANAC
Sequence: MRMNEPVDAQPAPSFLPMSRRFRGYLPVVVDVETGGFDWNKHALLEIACVPIEMGADGRFFPGETASAHLVPAPGLEIDPKSLEITGIVLDHPFRFAKQEKEALDHVFAPVRAAVKKYGCQRAILVGHNAHFDLNFLNAAVARVGHKRNPFHPFSVFDTVTLAGVAYGQTVLARAAQAAGLDWNAADAHSAVYDTEQTARLFCKIANAWPGPV
What is the function of this protein?
Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang.  Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A).  Also appears to be involved in tRNA biosynthesis.
What are the official names of this protein?
Ribonuclease T, Exoribonuclease T, RNase T.
What is the protein family that this protein belongs to?
Belongs to the RNase T family.
Protein: HGD_LEGPC
Sequence: MYLQGFGNYHHSEAVKGALPPNQNSPQHCNLGLYAEQLSGTAFTRPRHNNLRSWLYRILPTVTQGTYYPYEFNIMHSFVDEFSPNAMRWSPLYNSSQIKCDFVEGLFHIAGSPLVNTYTYYCNHSMSDKYFANNDGELLFVPYAGEIHLYTEFGKLMLSSGSIAVIPRGVKFKVEVISKEAKGYLCENSGNPLTLPQLGPIGANGLANPRHFQYPVAAFEDSGGEHTIICKNQKKLWFTVCNHSPLNVVAWHGNYAPYCYDLSLFNTINTVSFDHPDPSIFTVLTSESEIPGVSNLDFVIFPPRWMVAEHTFRPPYFHRNYMNELMGLVYGEYDAKKEGFIPGGISIHNCMTPHGPDYESYEIAASQDLKPNYINSLAFMFETKDYWQVTEQAYRHPSRQVDYLNCWQGFKVEFSQ
What is the function of this protein?
Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine.  Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, HGDO, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: CG050_HUMAN
Sequence: MAKQKRKVPEVTEKKNKKLKKASAEGPLLGPEAAPSGEGAGSKGEAVLRPGLDAEPELSPEEQRVLERKLKKERKKEERQRLREAGLVAQHPPARRSGAELALDYLCRWAQKHKNWRFQKTRQTWLLLHMYDSDKVPDEHFSTLLAYLEGLQGRARELTVQKAEALMRELDEEGSDPPLPGRAQRIRQVLQLLS
What are the official names of this protein?
Uncharacterized protein C7orf50.
Protein: RK23_ADICA
Sequence: MDKLKNQVITGKSIRLLQQNQYTFQVDLKLTKTGMKDWIERFFDVKVEGINSSRMTSKNGKKKNKLNITYVSYKKMIVRLKKNYFIPLFMSQT
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YUC7_ARATH
Sequence: MCNNNNTSCVNISSMLQPEDIFSRRCIWVNGPVIVGAGPSGLAVAADLKRQEVPFVILERANCIASLWQNRTYDRLKLHLPKQFCQLPNLPFPEDIPEYPTKYQFIEYLESYATHFDLRPKFNETVQSAKYDKRFGLWRVQTVLRSELLGYCEFEYICRWLVVATGENAEKVVPEFEGLEDFGGDVLHAGDYKSGERYRGKRVLVVGCGNSGMEVSLDLCNHDASPSMVVRSSVHVLPREVLGKSTFELSVTMMKWMPVWLVDKTLLVLTRLLLGNTDKYGLKRPEIGPLELKNTAGKTPVLDIGAISMIKSGKIKIVAGIAKFGPGKVELVDGRVLQIDSVILATGYRSNVPSWLKENDLGEIGIEKNPFPKGWKGKAGLYAVGFTGRGLSGASFDAMSVAHDIANSWKEETKQQIKTVATRHRRCISHF
What is the function of this protein?
Involved in auxin biosynthesis.  Belongs to the set of redundant YUCCA genes probably responsible for auxin biosynthesis in roots.
What are the official names of this protein?
Probable indole-3-pyruvate monooxygenase YUCCA7, Flavin-containing monooxygenase YUCCA7.
What is the protein family that this protein belongs to?
Belongs to the FMO family.
Protein: MNME_BACFR
Sequence: MNQDTICAIATAQGGAIGSIRVSGPEAITITGRIFTPAKSGKLLSEQKPYTLTFGRIYNGEEMIDEVLVSLFRAPHSYTGEDSTEITCHGSSYILQQVMQLLIKNGCRMAQPGEYTQRAFLNGKMDLSQAEAVADLIASSSAATHRLALSQMRGGFSKELTTLREKLLNFTSMIELELDFSEEDVEFADRSALRRLADEIEEVIARLANSFSVGNVIKNGVPVAIIGETNAGKSTLLNVLLNEDKAIVSDIHGTTRDVIEDTVNIGGITFRFIDTAGIRETSDTIESLGIERTFQKLDQAEIVLWMIDSADAISQLTLLSDKILPRCEHKQLILVFNKVELINETQKNELASQFSEHIGSEIESIFISAKQRLHTDELQQRLVAAAHLPTVTQNDVIVTNIRHYEALTRALDAIHRVQEGLDANISGDFLSQDIRECIFHLSDIAGEVTNDMVLQNIFAHFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_SALEP
Sequence: MVKLAFPRELRLLTPAHFTFVFQQPQRAGTPQITILGRLNSLGHPRIGLTVAKKNVRRAHERNRIKRLTRESFRLRQHELPAMDFVVVAKKGVADLDNRALSEALEKLWRRHCRLARGS
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: HUTH_AGRRH
Sequence: MTIVLRPGSVPLHHLADIYWNNGSAKLDPSFDAAVLKGAARIAEIAAGNAPVYGINTGFGKLASIKIDAADLATLQRNLILSHCCGVGAPLPENVVRLIMALKLISLGRGASGVRIELIRLIEGMLEKGVIPVIPEKGSVGASGDLAPLAHMSATMMGEGEAFYQGVQMPSKDALAKAGLSPVVLAAKEGLALINGTQTSTALALAGLFRAHRAAQSALVTGALSTDAAMGSSAPFHPDIHTLRGHKGQIDAGSALRNLLQGSEIRESHIEGDERVQDPYCIRCQPQVDGACLDLLASVARTLEIEANAVTDNPLVLSDNSVVSGGNFHAEPVAFAADQTALAVCEIGAIAQRRIALLVDPALSYGLPAFLSKKPGLNSGLMIAEVTSAALMSENKQMSHPASVDSTPTSANQEDHVSMACHGARRLLAMTDNLFGILGIEALAAVQGVELRGPLKTSPELEKAAAVLRSAVPVLEDDRYMATDLKAAIEVVASGALVSAISSGILPVLEA
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.