PharMolix/UniProtQA huggingface dataset:
Protein: YCF4_DAUCA
Sequence: MSCRSEHIWIQPITGSRKTSNLCWAIILFLGSLGFLLVGTSSYLGRNLISLFPSQQILFFPQGIVMSFYGIAGLFISSYLWCTISWNVGGGYDRFDRKEGMVCLFRWGFPGKNRRIFLRFLIKDIQSVRIEVKEGIYARRVLYMDIRGQGAIPLTRTDENVTPREIEQKAAELAYFLRVPIEVF
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: AEP2_CANGA
Sequence: MRKQVIGINNIFHLARIRSIPVHCHCKGPLYSYPVVSKTLFHTKNVEVSKYSHVELRSLNEQIHSQLTSLTDLNKRQLLLVETLSRNNNLEKLLDYYEIDEGSVEDAIQLLQDSNVSIQEFSSMIQPVLNRTNLVGKYHMGYLSKLMQIYISLTRTHNGGSVDALNKDDMNKFIKRFIEGSQLKRAQTALQFLLDGYKERGEDLLGPYGDKQTIAHFLMLRSGALQDLWKIDVSNGNNKKQAFYKINGSHRNVKSTYNVLDSVKLFEIVRYILRYNDKDNHSQPVYFDEGILKNVILCLGYVGQTTLIEDIINKIWELDSVSVPPKYNITVTSDLLTAIVSAYSKCGKSIQPGLVIADKFFGKIPNIIVKDDFWINLQKWNIILPNKWRSTIDLSKRTWELMKSWRNSTNNGGFITANVEFLNLVYKVLSSDYIKLKDLEWIYDIFQHSLVTLYSKNSLTVDEIKLLKKFQIFTIKKMVYFGHYSKCLQFIKEWSYDAANKQQLTNLFVVLRNRYLQKRGYNQEKEMTKVQKKYDEEEQEDMLLGGLW
What is the function of this protein?
Required for translation of the mitochondrial OLI1 transcript coding for the mitochondrial ATP synthase subunit 9.
What are the official names of this protein?
ATPase expression protein 2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AEP2 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PQRA_PROVU
Sequence: MAENVVNDILKWLETQLQRNEGIKIDTIANKSGYSKWHLQRIFKDFKGCTLGEYVRKRRLLEAAKSLQEKDMSILDIALMYGFSSQATFTRIFKKHFNTTPAKFRENGTMPDTHCFMSCETH
What is the function of this protein?
Regulatory factor of blood coagulation.
What are the official names of this protein?
Regulatory protein PqrA.
Protein: TBB_ACRCH
Sequence: MREIVHLQTGQCGNQIGAAFWQTISGEHGLDSNGVYNGSSELQLERMSVYFNEASGNKYVPRAVLVDLEPGTMDAVRAGPFGQLFRPDNFVFGQSGAGNNWAKGHYTEGAELVDNVLDVVRREAEGCDCLQGFQITHSLGGGTGAGMGTLLISKIREEFPDRMMATFSVVPSPKVSDTVVEPYNATLSVHQLVEHSDETFCIDNEALYDICMRTLKLSNPSYGDLNYLVSAVMSGVTTCLRFPGQLNSDLRKLAVNMVPFPRLHFFMVGFAPLTSRGAHSFRAVSVPELTQQMFDPKNMMAASDFRNGRYLTCSAIFRGKVAMKEVEDQMRNVQSKNSSYFVEWIPNNIQTALCAIPPRGLKMSSTFIGNSTSIQELFKRVGDQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDAGIDEEEEEYEEELPLEGEE
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Beta-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RL14_COXB2
Sequence: MIQTQSIVDVADNSGARRVMCIKVLGGSKRRYANIGDVIKVSIKEAIPRGKVKKGDVMHAVVVRTRKGVRRNDGSLIRFDNNAVVLLNNQLQLVGTRVFGPVVRELRTDKFMKIISLALEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: TRPD_ACIAD
Sequence: MNIQQALNHITKNIHLTQAQMEDVMRSIMQGEATEAQIGALMMGLRMKGESIDEITAAARVMRELAIKIDVSDIQYLVDIVGTGGDGQNLFNVSTASSFVIAAAGATIAKHGNRGVSSKSGSSDLLEQAGINLDLDMQQTERCIREMGVGFLFAPNHHKAMKYAVGPRRELGIRSIFNLLGPLTNPAGVKRFVIGVFSDELCRPIAEVMKQLGAEHVMVVHSKDGLDEISLASQTYIAELKNGEVTEWVLNPEDVNIPSQTLSGLIVEDSNASLKLIKDALGRKKSDIGEKAANMIALNAGAGIYVSGLATSYKQGVALAHDIIYGGQALEKMSILSEFTKALKEYANN
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: ZN789_HUMAN
Sequence: MFPPARGKELLSFEDVAMYFTREEWGHLNWGQKDLYRDVMLENYRNMVLLGFQFPKPEMICQLENWDEQWILDLPRTGNRKASGSACPGSEARHKMKKLTPKQKFSEDLESYKISVVMQESAEKLSEKLHKCKEFVDSCRLTFPTSGDEYSRGFLQNLNLIQDQNAQTRWKQGRYDEDGKPFNQRSLLLGHERILTRAKSYECSECGKVIRRKAWFDQHQRIHFLENPFECKVCGQAFRQRSALTVHKQCHLQNKPYRCHDCGKCFRQLAYLVEHKRIHTKEKPYKCSKCEKTFSQNSTLIRHQVIHSGEKRHKCLECGKAFGRHSTLLCHQQIHSKPNTHKCSECGQSFGRNVDLIQHQRIHTKEEFFQCGECGKTFSFKRNLFRHQVIHTGSQPYQCVICGKSFKWHTSFIKHQGTHKGQIST
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 789.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YBAS_BACSU
Sequence: MPLLTPTSVVLGVLLSQFLNGYEWAVPWIFAFITFAGSLSANFQSLRHALSHPLPMILALFVLHIFMPLFAWGSGHLIFKGDPLTITGLTLAVVIPTGITSLIWAAMYKGNVGLTLSIILVDTVLSPLIVPLSLSLLAGAQVHMDVWGMMKGLIVMVVIPSFLGMLFNQMSSPERTAFVSSALSPFSKLCLMAVIAINSSAIAPYFKSIDLRFAGIAVTVFFIALTGYAAAWLIGKMMKRRQEEIVSLIFTGGMRNISAGAVLAVTFFPSQVAVPVVIGMLFQQILAALFGYMLNRFELKPMLQKA
What are the official names of this protein?
Uncharacterized protein YbaS.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL4_GEOSE
Sequence: MPKVALYNQNGQTVGEIELNDAVFGIEPNKHVLFEAVIMQRASMRQGTHKTKNRAEVSGGGRKPWRQKGTGRARQGSIRAPQWRGGGTVFGPVPRSYSYKLPKKVRRLAIKSALSSKVLENDIVVLDQLSLEAPKTKEMVKILNNLSVDRKALIVTDELNENVYLSARNIPGVKVVPANGINVLDVLNHDKLVITKAAVEKVEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4, BL4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: PRS42_MOUSE
Sequence: MASGGGSLGLIVFLLLLQPKPCEAWAAASVLSTSGFPSGFSEAPRDNPPPPTRVRMSKATTRSPFMNFSLVCGQPFMKIMGGVDAEEGKWPWQVSVRVRHMHVCGGSLINSQWVLTAAHCIYSRIQYNVKVGDRSVYRQNTSLVIPIKTIFVHPKFSTTIVVKNDIALLKLQHPVNFTTNIYPVCIPSESFPVKAGTKCWVTGWGKLVPGAPDVPTEILQEVDQNVILYEECNEMLKKATSSSVDLVKRGMVCGYKERGKDACQGDSGGPMSCEFENKWVQVGVVSWGISCGRKGYPGVYTDVAFYSKWLIAVVNQADCLHPVVFLVLLLCSLTS
What is the function of this protein?
Plays a role in spermatogenesis.  Involved in germ cell survival during meiosis.
What are the official names of this protein?
Serine protease 42, Testis serine protease 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Lipid-anchor, GPI-anchor.
Protein: KS4_MESMA
Sequence: MKLKISFLILVLFSVFFAIEGIIKWFPASVNGKGHSSCTNGLEMTEEDFCKMLCGIDGKLRESKCVDHWCYCSQILFP
What is the function of this protein?
Reversibly inhibits potassium channels.
What are the official names of this protein?
Toxin BmTxKS4, KS3 toxin.
What are the subcellular locations of this protein?
Secreted.
Protein: COBQ_PSEA7
Sequence: MSDRGRTLMVQGTTSDAGKSTLVTALCRWLARRGVAVAPFKPQNMALNSAVTADGGEIGRAQAVQAQACRLAPHTDMNPVLLKPNTDIGAQVIIHGRAVTSMDAAAYHDYKRVAMEAVLASHARLAAAYRVVMVEGAGSPAEINLRANDIANMGFAEAVDCPVILVADIDRGGVFAHLVGTLELLSDSERERVRGFVINRFRGDIALLQPGLDWLEARTGKPVLGVLPYVSDLHLEAEDAIDTRQAAKTGPRLKVVVPVLPRISNHTDFDPLRLHPQVELSFVGPGQALPPADLIVLPGSKSVRADLAALRERGWDEAILRHLRYGGRLLGICGGLQMLGERLHDPLGLEGAAGSSAGLGLLALETTLEADKQLRNVQGRLSLEDAPLSGYEIHAGVTRGEALARPAVVLDDGRADGARSVDGNVMGTYLHGLFESTAACSALLRWAGLREVRAVDYQALRERDIERLADLVERHLDTGRLLALCGEPHA
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: PFP_TREPA
Sequence: MSISLLQQERHRYLPKVPDLLRGDFRRVCARRGLSTTAVADYDALRSLFARTYGQPLVNFVNASEKNEDSPMETAPEPRGLRVAIVLSGGQAPGGHNVIAGLFDGLKRWHADSVLIGFLGGPAGVLSGDHIEICADRVDAYRNTGGFDLIGSGRTKIESESQFAAAAQTVTRMALDALVVVGGDDSNTNAALLAEHFVNSGISTKVIGVPKTIDGDLKNEAIETSFGFDTATKTYSELIGNIARDACSARKYWHFIKLMGRSASHIALECALKTQPNVCLISEEVAAQSLTLAQIVQSLCDTIATRAQHGEHFGIVLVPEGLIEFIPEMKALITELNEVMARRAQEFEALDTPDAQRVWIEQALSASARAVFNALPAEISTQLLADRDPHGNVQVSRIDTERLLILQVTERLAQMKQEGTYTGVFSSIAHFFGYEGRCAFPSNFDADYCYTLGLTACLLAVHRFTGYVASVRNLTSSVAEWAVGGVPLTMLMNMERRHGSQKPVIKKALVDLEGMPFRVFSRRRASWALKTSYVYPGAVQYYGPPAVCDEPSVTIRLERPAPAANSSFGHRSS
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis.  Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis.  Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
What are the official names of this protein?
Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, 6-phosphofructokinase, pyrophosphate dependent, PPi-dependent phosphofructokinase, PPi-PFK, Pyrophosphate-dependent 6-phosphofructose-1-kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADA_THEON
Sequence: MKMEELVREIERLKEERNAIIMAHNYQLPEIQDIADFLGDSLELARKAVNVDADVIVFVGVDFMAETAKILNPEKTVLLPTRRATCAMANMLKVEHILKAKEQYPDAPVVLYVNTTAETKAYADVTVTSANAVRIVEKLDSDVIIFGPDKNLASYVAKMTGKKVIPVPEYGHCYVHRQFTLEDVERARKLYPNAKLMVHPECEPEVQERADIIVSTGGMIRRAPEHDEWVVFTEREMVYRLQRLYPDIKFHPAKEDAICIGMKAITLNHIYESLRDMKYEVEVPEDIAEKARRAIERMLEMS
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIMB_PORGI
Sequence: MNDAKKYIVSVLILLVAGMFGGCIKEDYSDCPRPFRLTVRAWDADMQDITETGAVQRVVIFVFDETGRRIDRLMMDAAQVAARKPIPLEYDGPTTVSFVAWANPDDHMLEETANVQNVKDLFFRLSSTDGIAQSPGDLFSGVLTCPIEYGSIEQGTDQTVDIYRRTAQVHIIIRGYQEWLEANGPRQLPDYADILLGETPDTYTGLAELIGNAVQYRPDGQIQNGDFISPIFRVYPTLDTTPLHLKLYAYGQELLNISTGSDGVPFIPVIGKMLNIYIDLRGANLNVLVSVTPWDVVQQYAEY
What is the function of this protein?
Anchoring subunit of the major fimbriae.  Regulates fimbrial length.  These filamentous pili are attached to the cell surface; they mediate biofilm formation, adhesion onto host cells and onto other bacteria that are part of the oral microbiome.  Fimbriae of P. gingivalis are major virulence factors.
What are the official names of this protein?
Major fimbrium anchoring subunit FimB.
What is the protein family that this protein belongs to?
Belongs to the bacteroidetes fimbrillin superfamily. FimB/Mfa2 family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RISB_THEFY
Sequence: MSGAGRPEYTVDAQGLTLGVVATRWNAEVVEPMLERALAAAEQCKVAETTVVRVAGAVEIPVVAQELARTHDAVVALGAVIRGDTPHFDYVCQSFTHGLTEVALRTEVPVGNGVLTCDTLEQARDRAGLPDSKEDKGWEAAVAALDTALVLRKLRDARGQRDGRPRPTTT
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: DRE1C_ARATH
Sequence: MNSFSAFSEMFGSDYESPVSSGGDYSPKLATSCPKKPAGRKKFRETRHPIYRGVRQRNSGKWVCELREPNKKTRIWLGTFQTAEMAARAHDVAAIALRGRSACLNFADSAWRLRIPESTCAKEIQKAAAEAALNFQDEMCHMTTDAHGLDMEETLVEAIYTPEQSQDAFYMDEEAMLGMSSLLDNMAEGMLLPSPSVQWNYNFDVEGDDDVSLWSY
What is the function of this protein?
Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'.  Binding to the C-repeat/DRE element mediates cold-inducible transcription.  CBF/DREB1 factors play a key role in freezing tolerance and cold acclimation.
What are the official names of this protein?
Dehydration-responsive element-binding protein 1C, Protein DREB1C, C-repeat/dehydration-responsive element-binding factor 2, C-repeat-binding factor 2, CRT/DRE-binding factor 2.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSMC_ACIAD
Sequence: MDPRSEVVLRQQQYLAIKILLINPPADELAQQLAHKHQVSVWTWNFADHQYFQHQSIQSDFAVTFPDQIPDQVIIFVPKSKELLSYLLHVVVSHLPAGQHIFLVGEKKGGVERASKQLQSYGKTVKLDSARHCQLWQTTIETTEQLKPLEQWLKHYSVKNENIQLEIYALPGVFSQNHLDIGTAVLLPYLNQIKLGKIADFGCGAGVISAYLAQLSPHNEIHALDIDAFALRSTEFTFQRNGLASERLHLHAVTGIQDAPKALDVIVSNPPFHQGIHTDYSASEGLCKTAKQHLNTSGELWIVANRFLNYPLLIEQTFGQCQVKTDQQGFKILYAKAT
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_BORPA
Sequence: MMTAEVTAADAEVLLAQPRGFCAGVDRAIDIVERALELHGAPIYVRHEIVHNRYVVEDLRGKGAVFIDELDQAPAGAIVVFSAHGVSQAVRGEAEARGLRVFDATCPLVTKVHIEVARMRAAGREIVMIGHKGHPEVEGTLGQAQGGMYLVETVEDVAALQVSDPGNLAYVTQTTLSVDDAAAVAGALKARFPGIVEPKKSDICYATQNRQDAVKLLAPECDLVLVVGSTNSSNSNRLREVAERKGVAAYLIDGAHAIDPAWLQGRRSIGITAGASAPEVLVQQVVERVRELGAVSVRTMPGLEESVAFPLPKGLSRKIAQTESLE
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: EXLYS_BPPM2
Sequence: MINKTTIKTVLITLGVLAAVNKVSALRSVKRLIS
What is the function of this protein?
Exolysin that catalyzes the cleavage of the host peptidoglycans during virus entry.
What are the official names of this protein?
Peptidoglycan hydrolase P7, Protein VII.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein. Note=Part of the capsid inner membrane.
Protein: LZTL1_MACFA
Sequence: MAELGLNEHHQNEYINYMRFARSKRGLRLKTVDSCFQDLKESRLVEETFTIDEVSEVLNGLQAVVHSEVESELINTAYTNVLLLRQLLAQAEKWYLKLQTDISELENRELLEQVAEFEKAEITSSNKKPILDITKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATSALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPED
What is the function of this protein?
Regulates ciliary localization of the BBSome complex.  Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation.  May play a role in neurite outgrowth.  May have tumor suppressor function (By similarity).
What are the official names of this protein?
Leucine zipper transcription factor-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the LZTFL1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C71DF_MENPI
Sequence: MELLQLWSALIILVVTYTISLLINQWRKPKPQGKFPPGPPKLPLIGHLHLLWGKLPQHALASVAKEYGPVAHVQLGEVFSVVLSSREATKEAMKLVDPACANRFESIGTRIMWYDNEDIIFSPYSEHWRQMRKICVSELLSSRNVRSFGFIRQDEVSRLLRHLRSSAGAAVDMTERIETLTCSIICRAAFGSVIRDNAELVGLVKDALSMASGFELADMFPSSKLLNLLCWNKSKLWRMRRRVDTILEAIVDEHKFKKSGEFGGEDIIDVLFRMQKDTQIKVPITTNSIKAFIFDTFSAGTETSSTTTLWVLAELMRNPAVMAKAQAEVRAALKEKTNWDVDDVQELKYMKSVVKETMRMHPPIPLIPRSCREECVVNGYTIPNKARIMINVWSMGRNPLYWEKPDTFWPERFDQVSKDFMGNDFEFVPFGAGRRICPGLNFGLANVEVPLAQLLYHFDWKLAEGMKPSDMDMSEAEGLTGILKNNLLLVPTPYDPSS
What is the function of this protein?
Hydroxylates (-)-(4S)-limonene to (-)-trans-isopiperitenol, a precursor of (-)-menthol, responsible for the cooling sensation of peppermint.  Fluorinated substrate analogs are hydroxylated with the same regio- and stereochemistry.
What are the official names of this protein?
Cytochrome P450 71D15, (-)-(4S)-Limonene-3-hydroxylase, Cytochrome P450 isoform PM2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: GSA1_LISMH
Sequence: MDHSMSKKLHDEALLHIVGGVNSPSRSNKGVGGGIPVTMERASGAYFYDVDGNKYIDYLAAFGPIITGHAHPHITEAITKAAQNGVLYGTPTKHEITFAKMLKEAIPSLEKVRFTNSGTEAVMTTIRVARAYTGRDKIIKFAGCYHGHFDLVLVEAGSGPSTLGIPDSAGVTKSTAEEVITVPFNDLASFKEALAVWSDQVAAVLVEPIVGNFGMVAPEDGFLEAVNELAHANGSLVIYDEVITAFRFMYGGAQNYLGVIPDLTAMGKIIGGGLPIGAYGGRVDIMEKVAPLGPAYQAGTHAGNPASILSGIACLEVLQEEGLYERFEKYGSMLKDGIEKAALKHGIAVTVNQIVGALTVYFTEDPVTNYAEAGATNGELFGRFFKGMLEEGINLAPSKYEAWFITSAHSEADILETIQAVDTVFGKMVQDN
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 1, GSA 1, Glutamate-1-semialdehyde aminotransferase 1, GSA-AT 1.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AFFL_DROMO
Sequence: MAQQQQQQHQQQQHHQQQQQLLLQQQQQLLQYNNNLYNLNYNMEDNERRKRREREKYERQQGIQSDDRETSLFGEPRRLNPSEGDAEITAALGEFIDARDHMNSSTVGIYRHASTNASSSRLPALSFGGSSLANSYSTSSASVNPAASLASSSASVPGQLPTSQQQQQQQQQQQHYQQQQRAPTYLKQADNKPPYNGRGGYPGQPMKNDIPSSSGMAPPRGPPRSSSSASQSNSNSNSINSSSATNNATSGATSASMSSPLGPPLSTQMPNGREKSFLGPPAPALPNGGRFVPPAASSKRPSNSVGLQPPPPEKDISKIITEMTNNYRVTPLTSIAATPHAPMSENYNLNGPNKFKYAFDSIGPLNSPPAAGASSLMTPLLAPIAPITSPIAPLLTTPPQASQLPLPLAPLAGATTVPPALGGMAAVAPIQQLMPTPPKASPTPPAIKPMKTEKNHSLEKQDSCLENDLELSESDDERKKEGRSAGNSSNSSESDSSESGSEASSKGDTQQQQQQQQQQQQQQLLLQQQQQQQLLLQQQQQRLAASANGSKKKYSQTIIASGANTISGLLTSSGLGGAGAGSVAGGAGGAGGAINATNNTCGGGGGSSGSCMGTMSSSSSSNKTPSPTDSNRWNLSRFFPKPANQTAAESVSPGVANAIGNVSMKVPGILPGGAQIIPESIDVTTAIVKNEKLHDEPRHVGDDEDDEADEQHRQQQQQQQQQQQQQQQQQRYGLSVTVKKEQLEQQQQQQLLLQQQQQLTTEQLALAGALPKNQIKRESRLSDSGSASSGSGSGSSSSDSAGGSSEVLQMPGPGETLQIPGVPAAITTVLRVPQAMQHKVQPNSVTLTPIGPLPASPKPRQKKPRKKKMSAATAPLDSSDEDEPTASSNKKHALELAATAAAAAAAVAVPVAAAAAPAIKKGRGRPRKQAQQQQQQQQQQLQQSGNLSSASASSSQAKGPTLTAAKKPLAKASVSNSNSTAPATVAAGTRKREHSSNSSSNSNTPTKKPTATFATMAAKLDRADALSSDDDSSSSSSCSSTKSSSSSGSDSETPAAAAAGAAASTATTVVTTSAQNPAKKRIVKINKVGVAGNSSSSSKAKRRYSVGSSSNSSSSSETEEQQQHKQQQLLLLQQQQQKQQLQHQQQLQQQQQQQQSLLGQFAAESLPQSAQRLSSSDCSSSSNSDSSSNSSGSSSSSDEDGEHRSGKRKSDKKKICTLTRIFNPKEGGAKKQGQVVIIDQSEEQQQQQQQQQQQAKELKPRATPTQLLGATLASPARTTTPHLTSLMCKIDLSKLARQHHHQPERLKAQQNGHLSSRSAEGARTPKDLQQICTPNGYVGGAAGGGAAASKLLGGVKHEHGVKPEPELEPGYEGKYKLNSVKQEFMLKQELPARRRKRSSSSSSSPYKEKKRKKEKAEQLSKELLPVPVLLPANNHERLSRDKLELLMQQQESAANGSPNKLQQQQQQSRLSQSQQQQQQQQQQQSLSQSTTAAATVAAAPIQLPTTCSEAVQTTPPPAAPQPEPRLIYRSHFDKEEENENDDLRKNDFLLQEAIRRKRAADSERDSFSQMTLYLEAIVYFLLTADAMERCNMEATWTMYKDTLSLIKYISSKNRPYQLSTNGNHESHNIVAILSLRCQSLISLKLYKLRRVNCRAIIASCTEFFRSGRGDILNGNTPSSISPSNSVGSQGSGSNTPPGKIVPQDIHNMLCKQNEYLTYVNSAHELWDQADRLVRNGNHIDFIRKLDHENGPLTLHSTMHEVFRYVQAGLKTLRDAVSYPQSQ
What is the function of this protein?
Has a role in transcriptional regulation.  Acts in parallel with the Ras/MAPK and the PI3K/PKB pathways in the control of cell identity and cellular growth.  Essential for regulation of the cytoskeleton and cell growth but not for cell proliferation or growth rate.  Required specifically for the microtubule-based basal transport of lipid droplets.  Plays a partially redundant function downstream of Raf in cell fate specification in the developing eye.  Pair-rule protein that regulates embryonic cellularization, gastrulation and segmentation (By similarity).
What are the official names of this protein?
AF4/FMR2 family member lilli, Protein lilliputian.
What is the protein family that this protein belongs to?
Belongs to the AF4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPO11_METTP
Sequence: MNLKVLKKTEDELRIEFEGERHTLLNLLRSELLEDERVVIATYDAKFPIMDNPVFRLKTRGVDPLDVIRDASARIADLCDEFLREYEEAVR
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit L.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WASF3_MOUSE
Sequence: MPLVKRNIEPRHLCRGALPEGVTSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEANNFYIRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFKSSTIQDQQVVSKNSIPNPVADIYNQSDKPPPLSILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQKEQKRVDGTTREVKKVRKARNRRQEWNMMAYDKELRPDNRLSQSVHHGASSEGSLSPDTRSHTSDVTDYSYPATPNHALQAQPATPSYTAGDAPLHGTTNQGAEHEYRPSSASARHMALNRPQQPPPPPPPQAPEGSQASTSVAPADYGMLPAQIIEYYSPSGPPPPPPPPMIPSAQTAFVSPLQMPTQPPFPASAVSTYPTPPHQPSTGLLATAPPPPGPPPPPPGPPGPSSLSSSPMHGPPVAEAKRPEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQEAKREPVGNDVATILSRRIAVEYSDSDDDSEFDENDWSD
What is the function of this protein?
Downstream effector molecules involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton.  Plays a role in the regulation of cell morphology and cytoskeletal organization.  Required in the control of cell shape (By similarity).
What are the official names of this protein?
Actin-binding protein WASF3, Protein WAVE-3, Wiskott-Aldrich syndrome protein family member 3, WASP family protein member 3.
What is the protein family that this protein belongs to?
Belongs to the SCAR/WAVE family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: DER_LEPIC
Sequence: MAKAVKKEIAKSEEVVSIKAPRKEPGKKIPVVSIVGRQNVGKSTLFNSLLKKKLAITEDYPGVTRDVLSARIYQEEKDLDFYLCDTPGLDIENPDSLSQTILETAYGQLRESDVIVFLLDKNLITTADHGLLNYLRREDKVANKPIIYCVNKADKELDEFDLEEFYRMGLSEVLPISAIGRKNLGLLLEKIQFFLKDKPGKVWIEKISASKKKEAQPLPLAEEDYEFRLAIVGKPNSGKSSLLNAICGYERAVVSDVAGTTRDSIDTLLEFGDRRLLLTDTAGIRKQSKTAEALEFYSYQRTIKAIESSDLVIHLLDAKKGFGDFDKKITSLLQEKGKPFLLAVNKWDSIEDKTDKTFKEYKEKLYSRFPLLNEVPIITISATERLRVQKLMDLSFDLASRSHRKVSTSELNKNLKNWMGLAGRSFSAHQPPKMLYCTQVSTSPFHLILFVNHVEYFKSNLVSFLKKKLTETYDLQGIPIRLEFRSDRK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: UPPP_BDEBA
Sequence: MSYLHAIILGIVEGITEFLPISSTGHMIIASSMMGIEDSSFTKAFEVIIQFGAIMSVLVLYWKRFLPHWGFYRKLFVAFLPTAIIGFVVKDVVEHLMGSVQVVAWSLIIGGVILIWADKAFAHLTMMGRKTDDLTYKDSVKLGLFQAIAMIPGVSRSGATIMGGLTLGMNKKEAAEFSFFLAVPTMAAATLYKLLKIYKTIEPAQINLLLVGCAVAFVVAMIAIKFFIGIVSRYGFRGFGYYRIVLGLVILILLYTGHDLQMV
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.