PharMolix/UniProtQA huggingface dataset:
Protein: FTSW_DICNV
Sequence: MSPRNSALERFRQHQKIPEKRWQRLAFPDVGLLLCWLALIVIGMVMVTSSSLSEAHVERLSTHHFAIRQGIFYVGSSIFAYIAFMLGTNFYREKAKFILGLAFLGLLLVYAPGIGVVVNGSRRWLNLGVINLQVGEFAKLAVFIFTAAYLQHHTQRLDHSWQPIIGLLAVTACFALMFYLQPDFGTMVVIVATVLGMLFLSGVSIWRLLLLGVLIAPAMVWVLISESYRLRRLTTFINPWEYQYDEGYQLVNSLISFGRGGLFGVGLGESVQKHQYLPEAHTDFIFSIIAEETGLVGALIVMAILMILVWRAFAIGYLADRMRKRFSSLLAYGIGLWLGLQSLINIGVTTGALPTKGLTLPLISYGGSSILMTSIALAILARIDAESRFIARLEGKI
What is the function of this protein?
Peptidoglycan polymerase that is essential for cell division.
What are the official names of this protein?
Probable peptidoglycan glycosyltransferase FtsW, PGT, Cell division protein FtsW, Cell wall polymerase, Peptidoglycan polymerase, PG polymerase.
What is the protein family that this protein belongs to?
Belongs to the SEDS family. FtsW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Localizes to the division septum.
Protein: ERG20_YEAST
Sequence: MASEKEIRRERFLNVFPKLVEELNASLLAYGMPKEACDWYAHSLNYNTPGGKLNRGLSVVDTYAILSNKTVEQLGQEEYEKVAILGWCIELLQAYFLVADDMMDKSITRRGQPCWYKVPEVGEIAINDAFMLEAAIYKLLKSHFRNEKYYIDITELFHEVTFQTELGQLMDLITAPEDKVDLSKFSLKKHSFIVTFKTAYYSFYLPVALAMYVAGITDEKDLKQARDVLIPLGEYFQIQDDYLDCFGTPEQIGKIGTDIQDNKCSWVINKALELASAEQRKTLDENYGKKDSVAEAKCKKIFNDLKIEQLYHEYEESIAKDLKAKISQVDESRGFKADVLTAFLNKVYKRSK
What is the function of this protein?
Farnesyl pyrophosphate synthase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway (PubMed:8096487).  ERG20 catalyzes the sequential condensation of isopentenyl pyrophosphate with dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate (PubMed:8096487).  The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.  Activity by the mevalonate kinase ERG12 first converts mevalonate into 5-phosphomevalonate.  5-phosphomevalonate is then further converted to 5-diphosphomevalonate by the phosphomevalonate kinase ERG8.  The diphosphomevalonate decarboxylase MVD1/ERG19 then produces isopentenyl diphosphate.  The isopentenyl-diphosphate delta-isomerase IDI1 then catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).  Finally the farnesyl diphosphate synthase ERG20 catalyzes the sequential condensation of isopentenyl pyrophosphate with dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate (PubMed:32679672).
What are the official names of this protein?
Farnesyl pyrophosphate synthase, FPP synthase, FPS, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Geranyltranstransferase.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
Protein: NOSZ_BRADU
Sequence: MSDSDNIKGVSRRTLLGTTAAAAGVGLAGGAVVTKDGAGFVSTADAQTKSAAPKAPPARPAVQKTEVAPGELDEYYVFFSSGQSGEMRIIGLPSMRELMRVPVFNRCSATGWGQTNESLKVLTEGMQPATREFLKNRGGTFMNGDLHHPHVSFTDGTYDGRYAFMNDKANSRVARVRLDVMKCDKIIELPNQHTVHGLRLQKYPRTGYVFCNGEDGVPLPNDGKVLDNPKEYHSIFTALDGDTMKVAWQVMVSGNLDNVDSDYQGKYCFSTCYNAEEGVTLAEMTANEQDWVVIFNLKRIEEAVKKGDFKEMNGVPVIDGRKGSPYTRYVPVSNNPHGMNTAPDGIHIVAAGKLSPTVTVMDVRLFDQLFDDKIKPRDVVVAEPELGLGPLHTAYDGKGNAYTTLFLDSQVVKWNIDLAKRAFKGEKVDPIIQKLDVHYQPGHNHSSMGQTKEADGKWLISLNKFSKDRFLNVGPLKPENDQLIDISGDQMKLVHDGPSFAEPHDATIVHRSKINPISIWDRADPMFADAVKQAKADGINLEADSKIIRDGNKVRVYMTSTAPAFGLEQFQVKQGDQVTVYITNIDAVEDLTHGFCIVNYGIQMEVAPMATASVSFSADKAGVYWYYCSWFCHAMHMEMKGRMFVEPKSV
What is the function of this protein?
Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
What are the official names of this protein?
Nitrous-oxide reductase, N(2)OR, N2O reductase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RS12_CHICK
Sequence: MAEEGITAGGVMDVNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFKCKK
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).  Subunit of the 40S ribosomal complex (By similarity).
What are the official names of this protein?
40S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS12 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ROCA_STAAR
Sequence: MVVEFKNEPGYDFSVQENVDMFKKALKDVEKELGQDIPLVINGEKIFKDDKIKSINPADTSQVIANASKATKQDVEDAFKAANEAYKSWKTWSANDRAELMLRVSAIIRRRKAEIAAIMVYEAGKPWDEAVGDAAEGIDFIEYYARSMMDLAQGKPVLDREGEHNKYFYKSIGTGVTIPPWNFPFAIMAGTTLAPVVAGNTVLLKPAEDTPYIAYKLMEILEEAGLPKGVVNFVPGDPKEIGDYLVDHKDTHFVTFTGSRATGTRIYERSAVVQEGQNFLKRVIAEMGGKDAIVVDENIDTDMAAEAIVTSAFGFSGQKCSACSRAIVHKDVYDEVLEKSIKLTKELTLGNTVDNTYMGPVINKKQFDKIKNYIEIGKEEGKLEQGGGTDDSKGYFVEPTIISGLKSKDRIMQEEIFGPVVGFVKVNDFDEAIEVANDTDYGLTGAVITNNREHWIKAVNEFDVGNLYLNRGCTSAVVGYHPFGGFKMSGTDAKTGSPDYLLHFLEQKVVSEMF
What are the official names of this protein?
1-pyrroline-5-carboxylate dehydrogenase, P5C dehydrogenase, L-glutamate gamma-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. RocA subfamily.
Protein: MURG_NITOC
Sequence: MAIRVLIMAGGTGGHIFPALAVADRLRAWGVEVVWMGTRHGLEAELVPKAGYPIEWISIGGLRGKGLTHWLRAPFKLLLALSQALRALRRWQPAVVLGLGGFVSGPGGLGAWLLRRPLLIHEQNAIVGTANRLLAPLAGRVMEAFPGTFPPARKAEWTGNPVRESIEQLSESRARLQARQGCFHLLVLGGSQGARILNETVPQALALLPTKVRPQVWHQCGSRQWEGAVVAYRAAGVEARLVPFIDDMAAAYAWADLVVCRAGALTVAELMAAGIGALLVPFPLAIDDHQRANADYLVVAGAALLLPEKELSPSRLAQEIERLGADYSTFISMAQAARQLHRVGAAQRVAERCLEVASG
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TCF25_MOUSE
Sequence: MSRRALRRLRGEQRGQEPLGPDALKFVLLDDDDAEEEGPKPGLGGRRPGGAGKEGVRVNNRFELINTEDLEDDLVVNGERSDCTLPDSVSSGNKGRAKHGNAETKQDGGATKAGSSEQSNASGKLRKKKKKQKNKKSCTGESSENGLEDIDRILERIEDSSGFSHPGPPPLSSRKHVLYVEHRHLNPDTELKRYFGARAVLGEQRPRQRQRVYPKCTWLTTPKSTWPRYSKPGLSMRLLESKKGLSFFAFDHNEEYQQAQHKFLVAVESMEPNNIVVLLQTSPYHVDSLLQLSDACRFQEDQEMARDLIERALYSMECAFHPLFSLTSGTCRLDYRRPENRSFYLTLYKQMSFLEKRGCPRTALEYCKLILSLEPDEDPLCMLLLIDHLALRARNYEYLIRLFQEWEAHRNLSQLPNFAFSVPLAYFLLSQQTDLPEHELSSARQQASLLIQQALTMFPGVLMPLLEYCSVRPDATVSNHRFFGPDAEISQPPALGQLVSLYLGRSHFLWKEPAIMSWLEENVHEVLQAVDAGDPAVEACENRRKVLYQRAPRNIHRHVILSEIKEAVAALPSDVTTQSVMGFDPLPPLDTIYSYVRPERLSPVSHGNTIALFFRSLLPNYTTEGERLEEGVAGGPNRNQGLNRLMLAVRDMMANFHFNDLEVPREDNPEGEGDWD
What is the function of this protein?
May play a role in cell death control.  Acts as a transcriptional repressor.  Has been shown to repress transcription of SRF in vitro and so may play a role in heart development (By similarity).
What are the official names of this protein?
Transcription factor 25, TCF-25, Nuclear localized protein 1.
What is the protein family that this protein belongs to?
Belongs to the TCF25 family.
What are the subcellular locations of this protein?
Nucleus. Note=Some staining in the cytosol; cytosolic localization is reduced in staurosporine-induced cell death.
Protein: PPK6_PERFU
Sequence: SDPEVPGMWFGPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-6, FXPRL-amide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYB_EPIBI
Sequence: MMKPERKTHPLLMIINNSLIDLPTPSNISYLWNYGSLLGITLVFQIMTGIMLAMHYSDNMDLAFSSMIHISRDVNYGWMIRFFHGNGASFFFICLYVHIGRSIYYNSYKLNYTWNIGIIILLLTMATAFLGYVLPWGQMSFWGATVITNLLSAIPYIGMTIVNWLWGGFAVSNATLTRFFSLHFLLPFIISAMVMIHLLFLHQTGSNNPLGLNSNTDKIPFHQYFSIKDLITMMLFIMILSFLVLFSPNILGDPENYIPANPLVTPIHIQPEWYFLFAYAILRSIPNKLGGVIALLMSIMILFFLPIFSKNCFSTSFNKWSGMIFWSFINIIILLTWIGANPVEAPYIIFGQILSVLYFLTFFWMPYSMVLFQKIIELL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HIS6_ACIF2
Sequence: MLASRVIPCLDIDHGRVVKGVQFVALRDAGDPVEVAKRYNDEGADEITFLDISASYEERGTLADMVSAVAAQVFIPLTVGGGVRCVEDIRTLLLAGADKVSINSAAVNDPELVRAAARRFGNSCIVVAIDAKRVEDHWEVFTHGGRRGTGLDAVAWAQRMAAYGAGEILLTSMDRDGTGIGFDLALTRAISDAVPVPVIASGGVGEIRHFVEGIQQGRADAVLAASVFHFGQFRISEVKARMAAAGIPVRTTR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGS_LODEL
Sequence: MSKIRTLNRQFISNLETHKAVTDAKRNLILSILKSTTTKREAKNYLTKYQNQFDLPDETPKAGTIYEQSLSRRDNQRELFIKRFLNAQNPFISIYDDEETKLQKIPLRLAIFKIKFPTISLRQWKGIAETFKRLMTLGISPIILLDYDHLSHGSFKKNELYMINQANKMLSILGKPEEQEDLKATILRNSFSVADGQITIDSLELILIPLYQGIIPIIQPIVFNADTTMQEFLKCNTLLNSLCTALVDRRTTDLLSIEKIVMIDPLGGIPSIERKQTSHVFINLSQEYSDIMSELFIGHISPKIRDLHVENLNSMNEILTSIFEKSGNDETTGIITTPEVMSIHNDQLNPIIYNVLTDRSIISSSLPSTNKRTPQLSTTIVKKGVDVQIFDQENNFSGSDFTMDNLIASKKVDKKKLTELLEDSFGKKLIVDEYYERINNRLATFILVGDYDGAAIITWEYSGDKKVAYLDKFAIAKRNQGLPGLADIIFKIILQSHPVELIWRSRKNNPVNKWYFERCCGCMSAPESQWKIFYTGDIFDKRIDRMKDKKKQNNKKKKTATMMMMNNSQKVAGVNADTHVDILKNLEQYSDICEGIVPSFA
What is the function of this protein?
N-acetylglutamate synthase involved in arginine biosynthesis.
What are the official names of this protein?
Amino-acid acetyltransferase, mitochondrial, Arginine-requiring protein 2, Glutamate N-acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: IWS1_ASPFU
Sequence: MSDSPEMQPASPSDVVSTHEFQRDLPEEPENAPTPGGDEDHNEEAPEEGAASATPAAESVAETHEDDPADKEDAGVDSDEESILSEVDEAQFEDFDPENVDIEDRPQLAIDEDNLKLIGRHKRKRTEEDGQQVKRKREGRREKKNRRRDMEEGLDEGEDKSRRRDRKKRDATPEDEELLDPATRRRRALDRAMDEALKKPTKRRFRKADGIDLEQMADAEIEDMRKRMTHAAQMDANNRREGRPAMHKLKMLPEVVSLLNRNQYVNSLVDPEINLLEAVKFFLEPLDDGSLPAYNIQRDLMTALSKLPINKETLIASGIGKVIVFYTKSKRPEPGIKRMAERLLAEWTRPILQRSDDYSKRVYQEAEYDPSPHAHKYYRKLTTRTTSAQASVAEARSRELLPPRLANRARPEITHTSYTIVPRPTVVQESKFARPLGASGEDRFRRMRARQIAASKGSRR
What is the function of this protein?
Transcription factor involved in RNA polymerase II transcription regulation.  May function in both SPT15/TBP post-recruitment and recruitment steps of transcription (By similarity).
What are the official names of this protein?
Transcription factor iws1.
What is the protein family that this protein belongs to?
Belongs to the IWS1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TPIS_LEGPL
Sequence: MRQKIVAGNWKMNGQIQQVTELVSQIEKLIGFDCAAQVAVMPPSIYIPKVRDCLRTGKIVVGAQNVYPKDYGAYTGELSAPMLKDFDCRYVLVGHSERRQFFHEDENFVAQKFHHVKDHGMIPVLCVGETLSERENGKTEQVIAQQVLAVSAKGKDCFRDCVVAYEPVWAIGTGKTATPEQAQKIHQFIRDLVGEINDSDAKHLTLIYGGSVNENNAKALFSMPDIDGGLVGGASLNAKQFVEIVKCIN
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCS2_KLEP3
Sequence: MPLADFHRSDPFTLGIELELQVVNPPGYDLSQDASTLIADVQHQLTVGEAKHDITESMLEIATGVCRDISHAQTQLSAIQQAVQRAALRHHLQICGGGSHPFHAWQRQQISDNPRYVKTVEHFGYLAQQATVFGQHVHVGCQSGDDALYLLHGLSRFVPHFIALNAASPWFDSTDSRFACSRLNRFSSYPDNGPMPWVADWQGFRRLFRQLSYTSMIDSMKDLHWDIRPSPQFGTVEVRVMDTPLTLAQAIHIAGFIQTLACWLLTERPFKHQPDDYLLYPFNRYQACRYGLDGTLTDVRSGEQRSIRQEILQLADRLAPFAHQLKATAALEAVVRQAKSPHSEAQQMRDFIANGGSLSGLVQKHCEIWAA
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: PUR9_LISMH
Sequence: MKRALISVSDKNGIVPFAEKLVELGVEIISTGGTKAAFEQAGVPVTGIEEVTEFPEMLDGRVKTLHPAIHGGLLARRDTAEHMEAIAAHDIKPIDLVVVNLYPFQETIQKSGVTLEEAIENIDIGGPSMLRSAAKNYAAVTVVVDTVDYDTVLTELEEHGATTFETRQRLAAKVFRHTAAYDALIAEYLTNITGETFPEKVTLTYNRKQVLRYGENPHQDAAFYTEPGTVENSISSAKQLHGKELSYNNIRDADAALKIASEFTEPVAVAVKHMNPCGVGVGENIEEAYLKAYEADETSIFGGIVALNKEVDAKTAEHMSKIFLEIIIAPSFSEEAFAILTKKKNIRLLTVPFAGSVKGFEKTSVNGGLLIQASDSVIEDTASYEVVTEKQPTEAEMKALIAQWKIVKHVKSNAIVVGSDKQTLGIGAGQMNRIGSALIALEQAGEKAKGAVLASDAFFPMDDTVEAAAKAGITAIIQPGGSIKDKESIAMANKYGISMVLTHVRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: DPO3A_STRCO
Sequence: MSKPPFTHLHVHTQYSLLDGAARLKDMFDACNEMGMSHIAMSDHGNLHGAYDFFHSAKKAGVTPIIGIEAYVAPESRRNKRKIQWGQPHQKRDDVSGSGGYTHKTMWATNSKGLHNLFRLSSDAYAEGWLQKWPRMDKETISQWSEGIVASTGCPSGEVQTRLRLGHFDEALKAAADYQDIFGKDRYFLELMDHGIEIEHRVRDGLLEIGRKLGIPPLVTNDSHYTYAHEATAHDALLCIQTGKNLSDPDRFRFDGTGYYLKSTDEMYAIDSSDAWQEGCANTRLIAEMIDTTGMFEKRDLMPKFDIPEGFTEITWFQEEVRRGMERRFPGGVPEDRQKQAEYEMDVIIQMGFPGYFLVVADFIMWAKNQGIAVGPGRGSAAGSIVAYAMGITDLDPIPHGLIFERFLNPERVSMPDVDIDFDERRRVEVIRYVTEKYGADKVAMIGTYGKIKAKNAIKDSARVLGYPYAMGDRLTKAMPADVLGKGIDLNGITDPTHPRYSEAGEIRSMYESEPDVKKVIDTAKGVEGLVRQMGVHAAGVIMSSEPIVDHAPIWVRHTDGVTITQWDYPQCESLGLLKMDFLGLRNLTIMDDAVKMVKSNKGIDLDLLSLPLDDPTTFELLQRGDTLGVFQFDGGPMRSLLRLMKPDNFEDISAVSALYRPGPMGMDSHTNYALRKNGLQEITPIHKELEEPLQEVLAVTYGLIVYQEQVQKAAQIIAGYSLGEADILRRVMGKKKPDELAKNFVLFQAGARKNGYSDEAIQALWDVLVPFAGYAFNKAHSAAYGLVSYWTGYLKANYPAEYMAALLTSVKDDKDKSAVYLNECRRMGIKVLPPNVNESMSNFAAQGDDVILFGLSAVRNVGTNVVESIIKCRKAKGKYASFPDYLDKVEAVVCNKRTTESLIKAGAFDEMGHTRKGLTAQYEPMIDNVVAVKRKEAEGQFDLFGGMGDEQSDEPGFGLDVVFGEDEWDKTYLLAQEREMLGLYVSDHPLFGLEHVLSDKADAGISQLTGGDFGDGAVVTIGGIISGLQRKMTKQGNAWAIATVEDLAGSLECMFFPATYQLVSTQLVEDAVVFVKGRLDKREDVPRLVAMELMIPDLSNAGTNAPVVLTIPATRITPPMVSRLGEILTHHRGDSEVRIKLQGPTKTTVLRLDRHRVKPDPALFGDLKVLLGPSCLAG
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The alpha chain is the DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase III subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_MYCA1
Sequence: MAATLRELRGRIRSAGSIKKITKAQELIATSRIGRAQARLDSARPYAFQITAMLTTLAAEAALDHPLLVERPEPKRAGVLVVSSDRGLCGAYNASIFRRAEELFSLLREQGKTPVLYSVGRKALNYYTFRNWDISGSWTGFSEQPQYENAAEIAETLVESFMRGTGGEDEGESDAESVDELHIVYTEFKSMLSQSAVAHRIAPMVVEYVEEPPEVRTLYSFEPDATTLFESLLPRYLTTRVYAALLESAASELASRQRAMKSATDNADDLIKALTLMANRERQAQITQEISEIVGGANALADAR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS17_CLOK1
Sequence: MERGYRKTRIGTVTSDKMDKTIVVAVENRVRHPLYGKIIKKTSKFKAHDENNEAKNNDKVLIMETRPLSKDKRWRLVEIVEKAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: SYC_SALNS
Sequence: MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHQDFDALNILRPDSEPRATHHIQEIIELTRTLIEKGHAYVADNGDVMFDVPTDPTYGQLSRQDLEQLQAGARVDVVDVKRNPMDFVLWKMSKEGEPSWPSPWGEGRPGWHIECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQSTCAHDGEYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARASLERLYTALRGTDKSAAPAGGEAFEARFVEAMNDDFNTPEAYSVLFDMAREVNRLKGEDMTAANAMASHLRKISGVLGLLEQEPDVFLQSGAQADDGEVAEIEALIQQRLDARKAKDWAAADAARDRLTEMGIILEDGPQGTTWRRK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK1_TRIV2
Sequence: MQLKQVIIAYKARDSQSKRWAELCAKQLENRNCQVLMGPSGPKDNPYPVFLASASQPIDLAIVLGGDGTVLTSARHLAPAGIPILGVNVGGHLGFLTESVDEFQDTEKVWDRLFEDRYAIQRRMMLQAAVYEGHRTNLEPVTERYLGLNEFCVKPASADRMITSILEMEIDGEVVDQYVGDGLIISTPTGSTGYTVSASGPIMHDGMEAITITPICPMSLSSRPLILPAGSVVSIWPLGDYDLSTKLWMDGVLATSIWPAHRVDIRMADCRAKFIVLRENNSYYQTLREKLLWAGTRVRYTSTQHN
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase 1, ATP-dependent NAD kinase 1.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNC_XANC8
Sequence: MTRPQAILTDIEGTTSSISFVKDVLFPYARRAMPAYVREHGGHPQVRHWLNQVADEIGEDVPDEVLITTLQTWIDEDRKHTALKALQGMIWEDGYRTADFSAHIYTDAAIQLQAWHAEGIPLYVYSSGSVPAQKLFFAHSDAGDLSGLVSDWFDTEVGPKRESSSYRRIAERIGVPAPEILFLSDVIEELDAAKRAGMRTALLDRLEDYPTPRSADDVGSHQRVESFTQLVL
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: TRPA_AQUAE
Sequence: MGRISDKFTELKEKREKALVSYLMVGYPDYETSLKAFKEVLKNGTDILEIGFPFSDPVADGPTIQVAHEVALKNGIRFEDVLELSETLRKEFPDIPFLLMTYYNPIFRIGLEKFCRLSREKGIDGFIVPDLPPEEAEELKAVMKKYVLSFVPLGAPTSTRKRIKLICEAADEMTYFVSVTGTTGAREKLPYERIKKKVEEYRELCDKPVVVGFGVSKKEHAREIGSFADGVVVGSALVKLAGQKKIEDLGNLVKELKEGLRE
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: MIAB_VIBC1
Sequence: MSKKLLIKTWGCQMNEYDSSKMADLLNAANGYELTEEPEEADVLLLNTCSIREKAQEKVFHQLGRWKTLKDKKPGVVIGVGGCVATQEGDHIRQRAPYVDVIFGPQTLHRLPEMIKQSQSDEAPVMDISFPEIEKFDRLPEPRAEGATAFVSIMEGCSKYCTYCVVPYTRGEEVSRPMDDVLFEIAQLADQGVREVNLLGQNVNAYRGPMHDGEICSFAELLRLVASIDGIDRIRFTTSHPLEFTDDIIAVYEDTPELVSFLHLPVQSGSDRVLTMMKRPHTGIEYKSIIRKLRKARPDIQISSDFIVGFPGETDKDFQDTMKLIKDVDFDMSFSFIFSPRPGTPAADYPCDLSEQVKKERLYELQQTVNTQAMRYSRQMLDTEQRVLVEGPSKKNLMELRARTENNRVVNFEGSADLIGQFVDVKITDVFANSLRGELVRTEKDMDLRSVISPTQMMAKTRREDELGVATFTP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YTHB_ECOLI
Sequence: MNKLPAHLSRQNCKIASTNLSEIIPRRAAVLK
What are the official names of this protein?
Protein YthB.
Protein: SPRT_PROMH
Sequence: MKTVRVPIALVQSVMRTLREKLQQANKYLNTDYPEPTLQYNQRGTIAGSAYYANWEIRLNPTLLIENKQNFIEEVIPHELAHLLVSRHFGRVAPHGKEWKWMMETVLQVSAKRTHHFDISNVTAKTFSYACRCQEIHQLTLRRHNKVQRGETQYRCRHCQAILQLIKE
What are the official names of this protein?
Protein SprT.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_BREDI
Sequence: ANNAGARKAIRKIEARTEVN
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: OCC1_DANRE
Sequence: MGCGNSTAASTTPGPAESAKDVQDDSSMDEEKRRNYGGVYVGIPADLTNETAGQTASTHKE
What are the official names of this protein?
Overexpressed in colon carcinoma 1 protein homolog, OCC-1.
What is the protein family that this protein belongs to?
Belongs to the OCC1 family.