PharMolix/UniProtQA huggingface dataset:
Protein: GLMU_MICLC
Sequence: MSQPSARPSAVIVLAAGQGTRMKSTTPKIMHAIGGRSLVGHALAAAWSLAPEHLVAVVRHERARVAEHIETVAAQLGIDALAIADQDDVPGTGRAVELGLAALPADLEGTVVVTYGDVPLLTPETLARLVADHEADGNAVTVLTATLEDATGYGRIVRDAEGLVERIMEHKDALAHAESTGDDSFVAIREVNSGIYAFDAALLRRTLPAISTDNVQGEKYLTDVLGMARDEGGRVASVGTQDVWEVEGANDRRQLSDLGRRLNERVLRHWMKEGVTVVDPSSTWVDVTVTLSSDVTLKPGTQLHGATSVATGAVVGPDSTLTDTQVGERAVVKRTDATEAVIGADASIGPFTYLRPGTVLGEEGRIGAFYETKKVTIGRGAKLSHLGYAGDAEIGEYTNIGCGNITANYDGVNKHRTVIGAHVRTGSNTVFTAPVTVGDGAYTGAGAVVREDVPAGALALNAVSQRTLEGWVPAKRPGTSSAEAARAAGAEGSGAQG
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APOE_TYMBA
Sequence: MKVLCTVLVVTLLAGCRADVEPEPEVLEPAVWKSGQPWELALGRFWDYVRWVQTLSDQVQEELLSSQVTQELTVLMEDTMKAVKAYKSELEQELVPMAEDTKARLSKELQAAQARLGADMEEVRNRLALYRNEMQAMLGQSAEELRARLASHLRKLRKRMLRDAEDLQKRLAVYKDGASEGAERGVSAIRERLGSLVEQSRVRAALTSQPLQERAQAWGKQLRGRLEEVRGQAQDRLEEVREQMEEVRVKIEEQAEAFQARLKGWFEPMVEDMRRQWADLIEKVQAAVGASTPAPTQNP
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR, the LDL receptor-related proteins LRP1, LRP2 and LRP8 and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.  A main function of APOE is to mediate lipoprotein clearance through the uptake of chylomicrons, VLDLs, and HDLs by hepatocytes.  APOE is also involved in the biosynthesis by the liver of VLDLs as well as their uptake by peripheral tissues ensuring the delivery of triglycerides and energy storage in muscle, heart and adipose tissues.  By participating in the lipoprotein-mediated distribution of lipids among tissues, APOE plays a critical role in plasma and tissues lipid homeostasis.  APOE is also involved in two steps of reverse cholesterol transport, the HDLs-mediated transport of cholesterol from peripheral tissues to the liver, and thereby plays an important role in cholesterol homeostasis.  First, it is functionally associated with ABCA1 in the biogenesis of HDLs in tissues.  Second, it is enriched in circulating HDLs and mediates their uptake by hepatocytes.  APOE also plays an important role in lipid transport in the central nervous system, regulating neuron survival and sprouting.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: DRE2_CRYHO
Sequence: MTQLIITYQSDSKLEESEVFLSELNRIKKEEDKFAKFSSLSDLRAIVKKGEFRIVSIYLSSGSILAEIFTFEFLKEFYGVLDFGSVLKVNILALDSIDKVKAFERNLLFSGFIKVKKLKGDGLNSSDSDFEIVIKAEKPSWKPEEGKVLVDDIDLEGSVPDIKNYVPLGQGKESCKSKERACNNCNCGRADLEKEIGIEAARKVYQEKVETGTARSSCGNCYLGDAFRCSGCPYKGMPAFKPGEKVSLANAEGDANDRTVDMNLIHEEKVDLITTTFDDDGSGVSNVQSKGGVLKLNI
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex.  Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase.  Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.
What are the official names of this protein?
Anamorsin homolog, Fe-S cluster assembly protein DRE2 homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: IXTPA_METCA
Sequence: MRRKLVLASNNAGKVRELQTLISTSGFEIVPQGALGIPEAEETGASFVENALIKAYHAARHSGLPAIADDSGLEVDALGGEPGVHSARYAGPAASDDDNIDRLLAALDGVEAGRRGARFRCVMVFVRDAEDTGPLIAEGCWEGWIGENRRGSGGFGYDPVFLVPGTGLSAAELPPEDKNRLSHRGQAAAVLASRLRALTGG
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: COAC1_ARATH
Sequence: MGSSQGSTLSADVMSLVDTLPVLAKTLIAGGAAGAIAKTAVAPLERIKILLQTRTNDFKTLGVSQSLKKVLQFDGPLGFYKGNGASVIRIIPYAALHYMTYEVYRDWILEKNLPLGSGPIVDLVAGSAAGGTAVLCTYPLDLARTKLAYQVSDTRQSLRGGANGFYRQPTYSGIKEVLAMAYKEGGPRGLYRGIGPTLIGILPYAGLKFYIYEELKRHVPEEHQNSVRMHLPCGALAGLFGQTITYPLDVVRRQMQVENLQPMTSEGNNKRYKNTFDGLNTIVRTQGWKQLFAGLSINYIKIVPSVAIGFTVYESMKSWMRIPPRERSKPA
What is the function of this protein?
Required for the accumulation of coenzyme A in the mitochondrial matrix.
What are the official names of this protein?
Mitochondrial carrier protein CoAc1, AtCoAc1, Mitochondrial coenzyme A transporter CoAc1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LIPA_ANADE
Sequence: MDAKKPSWLRVNVPGGERYQKVRETLKGLQLHTVCAEAHCPNVAECWGGGTATVMLMGDVCTRGCRFCNVKTAAHPPALDPDEPRHLAAAIAELGLDYIVVTSVDRDDLPDGGAAHFADAIRRLKEIPGLLVEVLTPDFRGDPAAVRTVGRAAPDVFANNLETVRRLTPAVRDAKATYDQTLGVLAQMKREFPQVVTKSSIMVGLGEQEAEVVEAMRDLRANGVEILTLGQYLRPSAWHLPVVEYVSPERFAAYRDQGLALGFRYVASGPLVRSSYRAAELFLRGEIESRTKPR
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2634_BACVZ
Sequence: MKVTYHGHSVIQVETKTHNIIFDPFLTGNSLTNLKPEEVKADVILLTHGHNDHVGDTEQIAKQNDALVIAPNELAVYLGFKGLKVHPMHIGGARQFDFGKVKLTQAFHGSAVTDEENKTITYTGMPAGILLTIDGKTIFHAGDTALFSDMKLIGELNHIDLAFLPIGDNFTMGPEDAKLAAEWLRAKQVVPVHYNTFPVIEQDPDAFAESLPGGVGKVMAAGETIELA
What are the official names of this protein?
UPF0173 metal-dependent hydrolase RBAM_026340.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: OXLA_OPHHA
Sequence: MNDFLLLLLVLFLGVPRSENHVINLEECFQEPEYENWLATASHGLTKTLNPKKIVIVGAGISGLTAAKLFREAGHEVVILEASDRVGGRIKTHREDGWYVDVGPMRVPQTHRIVREYIKKFNISLNPFRQTDENAWYLIKHVRQKMSANNPENFGYQLNPNERGKSASQLFDETLDKVTDDCTLQKEKYDSFSTKEYLIKEGKLSTGAVEMIGDFLNEEAGFHNSFLISVMDHFLFLNNSFDEITGGFDQLPERFFKDMDSIVHLNSTVEKIVHINNKVTVFYEGLSTNMRLVADYVLITATARATRLIKFVPPLSIPKTRALRSLIYASATKIILVCTDKFWEKDGIHGGRSITDLPSRVIYYPNHDFTNGIGVLLASYTWYSDSEFYTTLSDEKCVDVVMDDLVEIHNVSKDYLKSVCGKHVVQKWALDQYSMGAFSTYTPYQITHYSQMLAQNEGRIYFAGEYTAHPHGWIETSMKSAIREAINIHNA
What is the function of this protein?
Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids, thus producing hydrogen peroxide that may contribute to the diverse toxic effects of this enzyme (PubMed:17543361, PubMed:2044840).  Is very active against L-Lys, L-Phe, L-Leu, L-Tyr, L-Trp, L-Arg, and L-Met, moderately active against L-His, L-cystine, and L-Ile, and slightly active against L-Gln, L-Asn, L-Ala, and L-Val (PubMed:2044840).  L-Glu, L-Ser, L-Pro and Gly are oxidized very slowly (PubMed:2044840).  Its activity on platelet aggregation is controversial.  It has potent inhibitory activity on platelet aggregation induced by ADP and the thromboxane analog U46619, but not by thrombin, mucetin, ristocetin and stejnulxin (PubMed:17543361), but it has also been shown to induce platelet aggregation through the formation of hydrogen peroxide (PubMed:7886693).  It binds to bacteria and shows antibacterial activities by generating hydrogen peroxide.  Binding and antibacterial activities are higher against Gram-positive than against Gram-negative bacteria.  May also have an ability to induce hemorrhage, hemolysis, edema, apoptosis.
What are the official names of this protein?
L-amino-acid oxidase, LAO, Oh-LAAO.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SAMTR_HUMAN
Sequence: MEPGAGGRNTARAQRAGSPNTPPPREQERKLEQEKLSGVVKSVHRRLRKKYREVGDFDKIWREHCEDEETLCEYAVAMKNLADNHWAKTCEGEGRIEWCCSVCREYFQNGGKRKALEKDEKRAVLATKTTPALNMHESSQLEGHLTNLSFTNPEFITELLQASGKIRLLDVGSCFNPFLKFEEFLTVGIDIVPAVESVYKCDFLNLQLQQPLQLAQDAIDAFLKQLKNPIDSLPGELFHVVVFSLLLSYFPSPYQRWICCKKAHELLVLNGLLLIITPDSSHQNRHAMMMKSWKIAIESLGFKRFKYSKFSHMHLMAFRKISLKTTSDLVSRNYPGMLYIPQDFNSIEDEEYSNPSCYVRSDIEDEQLAYGFTELPDAPYDSDSGESQASSIPFYELEDPILLLS
What is the function of this protein?
S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes (PubMed:29123071).  Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling (PubMed:29123071).  Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 signaling (PubMed:29123071).  Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase (Potential).
What are the official names of this protein?
S-adenosylmethionine sensor upstream of mTORC1, Probable methyltransferase BMT2 homolog.
What is the protein family that this protein belongs to?
Belongs to the BMT2 family.
Protein: LPSA_DICNO
Sequence: MWEKCHRQWHKIKFYVKHAHLGLLPPAWLAKSAAAELERFERAPAELRAAIENRVHYYNALSQPFFLPETAPRVCHFPRQKPSSYYYDLKALLRYFPLEQRFSAQFGDVTTIPELPQFVKSRPITKNNENAVLLKLDSVRHFYLYPDRLPFRAKKSQLVWRGAAHQNHRIRFLEHFHQHPLCDVGCIHARSAAKPYHREFMSVKRQLQYRYILSLEGNDVATNLKWIMASNSLCLMPAPRYETWMMEGRLQAGVHYVQLRDDFADLEEQILFFERYPEAAEAIIKNAQQWMSQFARPETELWTALLVMKKYFSLLEPQ
What is the function of this protein?
Involved in lipopolysaccharide core biosynthesis.
What are the official names of this protein?
O-glucosyltransferase LpsA.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 90 family.
Protein: MURC_BURCJ
Sequence: MKHIVKHIHFVGIGGAGMSGIAEVLANLGYAVSGSDLSRNAVTDRLEALGARIAIGHDAANIEGANAVVVSTAVRSDNPEVLAARAKRVPIVQRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAEADESDASFLNLYPVIEVITNIDADHMDTYGHDFARLKQAFIEFTQRLPFYGSAVVCVDDPNVRQIIPFISKPVVRYGLSPDAQVRAEDIDARDGRMHFTVIREGRAPLAVVLNMPGLHNVQNALAAIAIATDLGVSDDAIQLALAEFNGVGRRFQRYGEVPSADGGQYTLIDDYGHHPVEMAATIAAARGAFPGRRLVLAFQPHRYTRTRDCFDDFVNVLSTVDALVLTEVYAAGEAAIPTASGDALSRALRAAGKVDPVFVATVDDVPDALAKVARNGDVVITMGAGSIGGVPAKLVQHIQQKA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSPA_BACAN
Sequence: MAVTGQVKWFNNEKGFGFIEVPGENDVFVHFSAIETDGFKSLEEGQKVSFEIEEGNRGPQAKNVIKL
What is the function of this protein?
Can bind to ATTGG and CCAAT motifs (Y-box motifs) of single-stranded oligonucleotides.
What are the official names of this protein?
Major cold shock protein CspA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYVM2_ARATH
Sequence: MILKTAFSLPTPTTTLLSPSSPHQLNTLFFTRRRRRLISPSRLNSIFSQRRFSFSAAASGNNVFTSPETSKTFDFSSEEKIYKWWESQGYFKPNFDQGGSPFVIPMPPPNVTGSLHMGHAMFVTLEDIMVRYNRMNGRPTLWLPGTDHAGIATQLVVEKMLASEGIKRVDLGRDEFTKRVWEWKEKYGGTITNQIKRLGASCDWSRERFTLDEQLSRAVVEAFVKLHDKGLIYQGSYMVNWSPNLQTAVSDLEVEYSEEPGFLYHIKYRVAGSPDFLTIATTRPETLFGDVALAVHPEDDRYSKYVGQTAIVPMTYGRHVPIIADKYVDKDFGTGVLKISPGHDHNDYLLARKLGLPILNVMNKDATLNDVAGLFCGLDRFEVREKLWADLEEIGLAVKKEPHTLRVPRSQRGGEVIEPLVSKQWFVHMDPLAEKALLAVENKELTIIPERFEKIYNHWLTNIKDWCISRQLWWGHRIPVWYVVGKDCEEDYIVAKSAEEALEKALEKYGKDVEIYQDPDVLDTWFSSSLWPFSTLGWPDVAAKDFNNFYPTNMLETGHDILFFWVARMVMMGIEFTGTVPFSHVYLHGLIRDSQGRKMSKSLGNVIDPLDTIKDFGTDALRFTIALGTAGQDLNLSTERLTANKAFTNKLWNAGKFVLHSLPSLSDTSAWENLLDLKLDKEETLLSLPLPECWAVSKLHILIDSVTASYEKLFFGDVGRETYDFFWSDFADWYIEASKSRLYGSGGNSVSLASQAVLLYVFENILKLLHPFMPFVTEDLWQALPYRKEALIVSPWPQNSLPRNVESIKRFENLQALTRAIRNARAEYSVEPVKRISASVVGSAEVIEYISKEKEVLALLSRLDLNNVHFSNAPPGDANLSVHLVASEGLEAYLPLAAMVDISSEVQRISKRLSKMQTEYDALITRLSSPKFVEKAPEEVVRGVKEQVEELEEKIKLTKARLDFLKSTTSLVSQ
What are the official names of this protein?
Valine--tRNA ligase, chloroplastic/mitochondrial 2, Protein EMBRYO DEFECTIVE 2247, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Mitochondrion.
Protein: TPIS_FRATF
Sequence: MQKLIMGNWKMNGNSTSIKELCSGISQVQYDTSRVAIAVFPSSVYVKEVISQLPEKVGVGLQNITFYDDGAYTGEISARMLEDIGCDYLLIGHSERRSLFAESDEDVFKKLNKIIDTTITPVVCIGESLDDRKSGKLKQVLATQLSLILENLSVEQLAKVVIAYEPVWAIGTGVVASLEQIQETHQFIRSLLAKVDERLAKNIKIVYGGSLKAENAKDILSLPDVDGGLIGGASLKAAEFNEIINQANKICTE
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ULAD_SHIB3
Sequence: MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGVRAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVAKEFNGDVQIELTGYWTWEQAQQWRDAGIQQVVYHRSRDAQAAGVAWGEADITAIKRLSDMGFKVTVTGGLVLEDLPLFKGIPIHVFIAGRSIRDAASPVEAARQFKRSIAELWG
What is the function of this protein?
Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P.  Is involved in the anaerobic L-ascorbate utilization.
What are the official names of this protein?
3-keto-L-gulonate-6-phosphate decarboxylase UlaD, 3-dehydro-L-gulonate-6-phosphate decarboxylase, KGPDC, L-ascorbate utilization protein D.
What is the protein family that this protein belongs to?
Belongs to the HPS/KGPDC family. KGPDC subfamily.
Protein: RSMF_KLEP3
Sequence: MAENTVYFPEAFLAQMRAAMPAHLSFDDFIAACQRPLRRSIRVNTLKISVADFLSLVAPYGWQLTPVPWCEEGFWIERDGDDALPLGSTAEHLSGLFYIQEASSMLPVAALFADNPQPERVMDVAAAPGSKTTQIAARMGNAGGILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAALPEAFDAILLDAPCSGEGVVRKDADALKNWSPESNLDIAATQRELIDSAFHALRPGGTLVYSTCTLNREENQSVVQWLLSRYPQAVEILPLGDLFSGAADALTAEGFLHVFPQIYDCEGFFVARLRKTAAIDPLPAPGYKVGKFPFTPLKSREAAAVTAAANAVGLAWDAGHTLWQRDKELWLFPQAMEPLFGQVRFSRIGVRLAEVHNKGYRWQHEAVIAFAAPQRAFELTQEEAEEWYRGRDVYPQTAPQQDEAIVTFQGVPLGLAKRVGSRLKNSYPRELVRDGKLFAGKV
What is the function of this protein?
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase F, 16S rRNA m5C1407 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmF.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPC1_GIAIN
Sequence: MEPNRRLRYFRSEIPQPVTEHRFPKRVEKLVFSVLSSNALMKLSEVQITTPILYEHYPSPATNGVLDKRLGLSDKVGKCATCGKDTKMCIGHFGTISLALPVFHPGLINDARTMLSIVCPFCSRVKISEADRLKYKVLNHKFSLAIVKEAQEQAKKQVNCPFCHAPSTICKKSQGFRVLREMHYEERATKILADVIKHQKDIEKIQELDQRLRNHVVDPIQALHILQKVPECDYPYLGIPWQSRNVYASQQTPDSIASNDASQLFSRGSSKLLARTASRFIAQHQGISDRATRLTSHAFLTRPQDVILTHIPVPPSCLRPSVQSGSGAGTTEDNLTSHLVRILTINDKLKEAMVSGAVATSKVYAKWDQLNMDVSLLYIGKIPGGVQPVKNKTDSGTKEGTGIIDRLKGKAGRFRSNLSGKRVNFSGRTVISPNPYLSMQQVAIPRLIAQNLTFPEIVTSRNIRFLRELILNGKTYPGANEVLLLNDTIRYNPALKRLGIDVKQSRDMEAKAMELVSRCVDTFNLNSLCADLPELQAAIQHLVSESSNAINSELKAEDLPQNQPLFAKEVYDPAQKGESNNIDNNVCEIDELKLEDTADYQVGESAGQASTVAVEQPPESRTVLKLNSIASLQLTNASSQHLSTFKLNTVSLLQKDRRGRQAIANSLRPNDIVYRHLLPNDTLLFNRQPSLHRMSIMQFNAVIHENRTFSFNPVVCSPFNADFDGDEMNIFYMQGQEARAEAGILMGSHENIISPRHGECMIGLTQDFLTGIYLLSGKGIFMTRQEYCQHVSYGCDGFGDATYGVSLYNYGREFIKSIHDRRGTEEDTVGFVKVPCLSQPCIVYPRQLYSGKQVLSVLMKGNDFDSVNINLEHGDKTYKKDSDRRALSVNDDYIIIQNSEHLVGRLTKTFLASSKNCIFYFLVQNYGPVSAARIMLRFAKVAARFLMNYGFTIGIDDVMPSQRVLGKKEVIVQEGYEKAQEKIRDYESGKLEAIPGSTVQETLEATLNQILSNVRESCAQIALKELHFTNKPLIMSLCGSKGSPINIAQMIIILGQQSFGGSRAPDDFYTRSTPYFYHYSKEPNAKGFILNSFYTGLLPFEFLAHARAGRDGVIDSACKTADTGYLQRRLVKCLEDLSVSYDFTVRNSKKSVVQFRFGHDGFDPIKLEVGTGQCFDLDTLLRHIILLNRSQDLAEGAFPVLLDRYKAEAELDVLLNKDFYGQEACLIERSNVTSYFQQSILPKLTTNTHIATTVAPALAASFLQTTLTKKDIDDFLRQVRRKYIRLNLEPGSPCGAVAAQSVGEPSTQMTLKSFHHAGLASMNITQGVPRLKEIVDGVVKISTPITTVELHVDVDKEELAATVTEKYLEKARMMKNIIECTYLGQISASIIECYSQSVCHIEVNLDMKIIADMGLAGIITVETVVASILHNDKAKKLVGQDQSSGSVSIHSATRFSVRPLTQSRDDLLFDIQSLKLLLPMIPVSGISTCSRAVINEYKEFCQGATSSAPLTKYNLLVEGIGLQNILNVSGIDFTRTLSNNIVEVANTLGIEAAVATISNEIKACMDSHGMAVDMRHIRLLADIMCFRGRVLGFTRFGLTKMKADSVIMLASFEKTGEHLFNAALGNKVDEANGVTESIILGKPMSMGTGSFSLLQAPYFDEKTGKTIEYQPKQTTRFLGEVLNKQYDEEVDAIVNAFWYDEKLYLTGAEAKAKLLRGRRHANKRSWSRGKERHASLKPKNR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Largest and catalytic core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.  Forms the polymerase active center together with the second largest subunit.  A single-stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol III.  A bridging helix emanates from RPC1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol III by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase III subunit RPC1, RNA polymerase III subunit C1, DNA-directed RNA polymerase III largest subunit, RNA polymerase III subunit C160.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
What are the subcellular locations of this protein?
Nucleus.
Protein: STC_DROME
Sequence: MAEYWQQLTNGAGEAGPGNESSAMADCNGGHESAAVGGSCNRHSNNNYVNFNQFIMQHNLGGGAPSNATSTMQHPVGSSYTNFSLGGGGGAFGLNPPVASASTSHFANVSHQSPNFYSQAMIPTYQNGDGIARVTVTSSYGSVNPSNSNFSSFYTPFGNNPFDFSASKLQASAPEFVPNFAKLSLEETPAAATTNGNSTASLETAINETRPRTLRAQEPAERGANNQCSNHNYERERERERDRDRDRERDRDRDRDRDRDRDRDRDRDSRPGNTRQQRRSDYRDDREDRYERSDRRRPQKQQRYDNHRSNKRRDDWNRNRDRINGFPRAVDDLDTSNESAHPSPEKQSQLQQISPRRGPPLPPADNEKLSQREKLVRDIEQRRLECLVCVEAIKSHQPTWSCRNCYHMLHLKCTITWASSSKSEVGWRCPACQNVLQDLPRDYLCFCGKLKNPPVSRTELAHSCGEVCCRIEGCSHACTLLCHPGPCPPCQANVVRSCGCGRSTKTMQCAMKEEVLCGEICDKLLNCGEHRCQAECHSGKCAACSEQVVQQCHCGKQERKVPCTRESQDKRTYSCKDSCGQPLPCGHHKCKDSCHAGSCRPCKLSPEQITSCPCGKMPVPAGQRSSCLDPIPTCEGICSRTLRCGKPAHPHQCGSKCHLGQCPPCPKQTGVKCRCGHMDQMIKCRQLCNRADDARCKRRCTKKRSCGKHKCNVECCIDIDHDCPLPCNRTLSCGKHKCDQPCHRGNCPPCYRSSFEELYCECGAEVIYPPVPCGTKKPICKLPCSRIHPCDHPPQHNCHSGPTCPPCMIFTTKLCHGNHELRKTIPCSQPNFSCGMACGKPLPCGGHKCIKPCHEGPCQSAGEICRQSCTKPRPTCGHKCAAACHEGACPETPCKELVEVQCECGNRKQNRSCQELAREHSRIATIQLASSMAEMSRGNYMELSEILAPAKKSNKTLDCNDECRLLERNRRLAAALSSGNSDTKQKCLTKYSEFVRGFAKKNPALTKSVYETLTDLVKLAKESKQRSRSHSFPTMNREKRQLVHELCEVFGIESVSYDKEPNRNVVATAHKDRCWFPATSIMEVLARESGQRRVPVPSNNAWGLKK
What is the function of this protein?
Plays an essential role during the late stages of embryonic neurogenesis.  May either fine-tune the guidance or the spatial maintenance of the migrating SNB and in nerve roots, which are composed of axons originating from distinct groups of motor neurons and may be required to either guide or maintain the position of these nerves along a direct and straight path to their ultimate targets in particular muscle fields.  May play a role in egg chamber development and/or may confer essential maternal contributions to the early embryo.
What are the official names of this protein?
Protein shuttle craft.
What is the protein family that this protein belongs to?
Belongs to the NFX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PROQ_SALCH
Sequence: MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVERVGGEMNLSKTQLRSALRLYTSSWRYLYGVKPGATRVDLDGNPCGELEEQHVEHARKQLEEAKARVQAQRAEQQAKKREAAAAAGEKEDAPRRERKPRPVARRKEGAERKPRADKPTTKAPRAPREEKHTPVSDISVLTVGQSLKVKAGNNAMDATVLEITKDGVRVQLNSGMSLIVRAEHLVF
What is the function of this protein?
RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.  May regulate ProP activity through an RNA-based, post-transcriptional mechanism.
What are the official names of this protein?
RNA chaperone ProQ.
What is the protein family that this protein belongs to?
Belongs to the ProQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPX_METI4
Sequence: MFKRIFLLTLTNIAVIFLLTLFISLLHLDRWLNAYGIDYQTLFLFSMVVGFTGSFISLAISKWMAKMAYNIHVIQEPSNEAERWLVETVAELAKRANIRMPEVGIYESPEVNAFATGPSRSNALVAVSTGILSQMNKKQIAGVLAHEITHINNGDMVTMTLLQGVVNTFVVFLSRIIGFFVDRLFSRNEERESIGIGFYLGMFISEIVLGLLASIIVAWYSRMREFRADAGGAHLAGKEAMISALKKLKQIMEGESAFIDERSPALNAFKINGRPGGILALLATHPPLDERIKALERIPD
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.