PharMolix/UniProtQA huggingface dataset:
Protein: DEOD_ECO8A
Sequence: MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVLPHVKLRDVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGIDARVGNLFSADLFYSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAERQTTFNDMIKIALESVLLGDKE
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: RS2_FLAPJ
Sequence: MANKIEVKDLLEAGVHFGHMTRKWDPNMAPYIYMERNGIHIINLYKTAAKIEEANEALKKIAASGRKILFVATKKQAKDIVAEKAAAANMPYITERWPGGMLTNFVTIRKAVKKMSTIDRMKKDGTFMTLSKKERLQVDRLRAKLEKNLGSISDMSRLPAALFVVDIKAEHIAIKEAQKLNIPVFAMVDTNSDPRLVEYVIPANDDASKSIDKILTLVTEAIIDGLANRTSDKEADTTTEEVAQEEVTDTKADEKAIVAEAAKTKE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RNPH_PSEPW
Sequence: MKRPSGRAADQLRSIRITRNYTKHAEGSVLVEFGDTKVICTVSVENGVPRFLKGQGQGWLTAEYGMLPRSTGERNQREASRGKQGGRTLEIQRLIGRSLRAALDMSKLGDITLYVDCDVIQADGGTRTASITGAMVALVDALAVIKKRGGLKAGNPLKHMIAAVSVGMYQGEAVLDLDYLEDSAAETDLNVVMTSAGGFIEVQGTAEGAPFQPEDFNAMLALAQKGMNEIFELQQVALAD
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: NAGB_OENOB
Sequence: MKLEIINSQIEAGQKGLQIFKQAIQQGAQVFGLATGSTPISIYDAITQSDLDFTKFISINLDEYKGLANNHPESYHYFMNKYFFSKKPFAHSYMPNGLADDLKSETKHYDQIIEENPIDLQILGIGRNGHIGFNEPGTSFNSQTHIVNLTDNTIQANSRFFDSIDQVPKQAVSMGIASIMKSKEILIAAYGKEKAQAVKEFIEGPVTEDVPASILQKHPKVTVILDQAAAALLSKK
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: NS1_I40A0
Sequence: MDPNTVSSFQVDCFLWHVRKRVADQELGDAPFLDRLRRDQKSLKGRGSTLGLNIETATRVGKQIVERILKEESDEALKMTMASAPASRYLTDMTIEEMSRDWFMLMPKQKVAGPLCIRMDQAVMDKSIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTNEDVKNAIGVLIGGLEWNDNTVRVSKTLQRFAWRSSNENGGPPLTPKQKRKMARTIRSEVRRNKMVD
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: BIOB_BRASO
Sequence: MQGAPLRHDWTREEAEVLYALPFPDLMFLAQATHRRHFDPTRLETASLLSIKTGGCPEDCGYCSQSAHYDTGLKATKLMDQDAVVATARRAKEAGADRFCMAAAWRNPKDRDLDQVCDMVSAVKDLGMETCVTLGMLTPPQAARLKQAGLDYYNHNVDTSPEFYDRIITTRTMQDRIDTLANVREAGIKVCCGGIIGMGEEVDDRLGMLVLLANLDAHPDSVPINMWNEVKGVPVNDTAERPDGIALARLIAVARIMMPRSVVRLSAGRQYMSDELQSLCLLAGANSIFIGDVLLTTANPQAERDADLLTRLGMTSSLSARSVAAVDENVSANA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: ILVD_BACCQ
Sequence: MRSDMIKKGFDKAPHRSLLKATGLKDEDFDKPFIAICNSFIEIIPGHKHLNEFGKLVKEAVRAAGMVPFEFNTIGVDDGIAMGHIGMRYSLPSREIIADSVETVVNAHWFDGMICIPNCDKITPGMMMAALRINIPTVFVSGGPMAAGKTSKGEVVDLSSVFEGVGAYQSGKISEEELKDIEDHGCPSCGSCSGMFTANSMNCLCEVLGLALPGNGSILAIDPRREELIKQAAEKLKILIERDIKPRDIVTEEAIDDAFALDMAMGGSTNTVLHTLALAHEAGLDYDMSRIDAVSRRVPHLCKVSPASNWHMEDIDRAGGISAILKEMSRKEGVLHLDRITATGQTLRENIAHAEIKDKEVIHSLENPHSEEGGLRILKGNLAKDGAVIKSGATEVKRFEGPCVIFNSQDEALAGIMLGKVKKGDVVVIRYEGPRGGPGMPEMLAPTSAIAGMGLGADVALLTDGRFSGASRGISVGHISPEAAAGGTIALLEQGDIVCIDVEERLLEVRISDEELDKRKKEWKRPEPKVKTGWLGRYAQMVTSANTGAVLKVPNFD
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: DEN6A_MOUSE
Sequence: MALPGPAVFGPGSRGSLDEAGAEGREAAALAAAGVALEDEEEDDGRRGLLRWDGFSAWLHCVCVVGFDLELGQAVEVIYPQHSKLTDKEKTNICYLSFPDSNSGCLGDTQFCFRFRQSSGRRVSLHCLLDEFDKDLPVYLKKDPAYFYGYVYFRQVRDKTLKRGYFQKSLVLISKLPYIHFFHTVLKQIAPEYFEKNEPYLEAACNDVDRWPAPVPGKTLHLPIMGLVMKVRIPTCHDKPGTTQMVQLTQQADTHTSIILPTVHEVDLFRCFCPVFLHSQMLWELVLLGEPLVVMAPSPSESSETVLALVNCISPLKYFSDFRPYFTIHDSEFKEYTTRTQAPPSVILGVTNPFFAKTLQHWPHIIRIGDLKPAGEIPKQVKVKKLKNLKTLDSKPGVYTSYKPYLNRDEEIIKQLQKGIQQKRPSEAQSVILRRYFLELTQSFIIPLERYVASLMPLQKSISPWKSPPQLRQFLPEEFMKTLEKTGPQLTSGIKGDWIGLYRQFLKSPNFDGWFKTRRKEMTQKLEALHLEALCEEDLLLWIQKHTEVETVDLVLKLKNKLLQAGRESLPVKPDTVEKLRTHIDAIILALPDDLQGILLKTGMT
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) for RAB14.  Component of an endocytic recycling pathway that is required for the control of ADAM10 transport, shedding of N-cadherin/CDH2 by ADAM9 or ADAM10 and regulation of cell-cell junctions.  Required for RAB14 recruitment to recycling endosomes (By similarity).
What are the official names of this protein?
Protein DENND6A, DENN domain-containing protein 6A.
What is the protein family that this protein belongs to?
Belongs to the DENND6 family.
What are the subcellular locations of this protein?
Recycling endosome. Cytoplasm.
Protein: RIMS4_HUMAN
Sequence: MERSQSRLSLSASFEALAIYFPCMNSFDDEDAGDSRRLKGAIQRSTETGLAVEMPSRTLRQASHESIEDSMNSYGSEGNLNYGGVCLASDAQFSDFLGSMGPAQFVGRQTLATTPMGDVEIGLQERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLFPESPQGKVLQVIVWGNYGRMERKQFMGVARVLLEELDLTTLAVGWYKLFPTSSMVDPATGPLLRQASQLSLESTVGPCGERS
What is the function of this protein?
Regulates synaptic membrane exocytosis.
What are the official names of this protein?
Regulating synaptic membrane exocytosis protein 4, RIM4 gamma, Rab3-interacting molecule 4, RIM 4.
What are the subcellular locations of this protein?
Synapse.
Protein: RS3_SYMTH
Sequence: MGQKVHPKGLRIGIVKDWDTRWYADKRNFSDLLVEDVKIRKYIKKTLYAAGISRIEIERAGGRIRIIVHTAKPGMVIGRQGQGIAELQNQLAQMTGKQISLDVKEIRLPELDAQLVAESIAQQLEKRMSHRRAMKQAIQRAMRLGAQGVRIIVSGRIGGAEIARSERAWEGTVPLHTLRADIDYGFAEADTTFGKIGVKVWIYAGEAAQKAAAGDRRERGERRERGGRRGGRGRGQGGQRMSREERAALERAAIEAGPKPVNREGGQ
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: SPB5_PLEMO
Sequence: MDALQLANSAFAVDMFKQLCEKEPVGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFENVKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVSNQTKILVVNAAYFVGKWMKKFPESETKECPFRVNKTDTKPVQMMNIEATFCMGNIDSIDCKIIELPFQNKHLSMFILLPKDVEDESTGLEKIEKQLNSEALAQWTNPSTMANAKVKLSIPKFKVEKIIDPKASLENLGLKRIFSEDTSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPGARILQHKDELNADHPFVYIIRHNKTRNIIFFGKFCSP
What is the function of this protein?
Tumor suppressor.  It blocks the growth, invasion, and metastatic properties of mammary tumors.  As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity (By similarity).
What are the official names of this protein?
Serpin B5, Maspin, Peptidase inhibitor 5, PI-5.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Ov-serpin subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: PURA_PECAS
Sequence: MGKNVVVLGTQWGDEGKGKVVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVVSIIGNGVVLAPDALMKEMTELEARGVPVRERLLLSEACPLILPYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAVKLKEIVEYHNFQLVNYYKVDAVDYQKVLDDVLAIADILTAMVVDVSDLLYKAHLRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGIVKAYSTRVGAGPFPTELFEEVGEHLSQKGNEFGATTGRRRRTGWLDAVAVRRAVQINSLSGFCLTKLDVLDGLKEIKICVGYRLPNGTEVDTTPLAAEGWEGLEPIYETVPGWSESTFGVKDHSKLPQAALNYIKRIEEITGVPIDIISTGPDRSETMVLRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_BRUME
Sequence: MTDTTKIDYSKTLYLPQTEFPMRAGLPQREPLFVQRWEEMNLYKKLREQAKDRPLYVLHDGPPYANGNIHIGHALNKILKDVITRSFQMRGYNSNYVPGWDCHGLPIEWKIEEKYRAAGKNKDEVPINEFRKECREFASNWIRVQTEEFKRLAILGDFENPYTTMNFHAEARIAGELLKFAASGQLYRGSKPVMWSVVERTALAEAEVEYHDIESDMIWVKFPVAGEVATENDLSGSAVVIWTTTPWTIPGNRAVSYSSRIEYGLFEITEAENDFGPRPGERLVFADKLVEECCAKAKLQFKRLRSVSAEELGKIVLDHPLKGFGGGYEFVVPMLDGDHVTDDAGTGFVHTAPSHGREDFEAWMDNARQLEARGIDPNIPFPVGDDGFYTKDAPGFGPDREGGPARVIDDNGKKGDANKVVIEQLIAADKLFARGRLKHSYPHSWRSKKPVIFRNTPQWFVYMDKNLGDGTTLRSRALKVIDETRFVPTAGQTRLRSMIEGRPDWVLSRQRAWGVPICVFVDEEGNILQDDAVNKRIMDAFEKEGADAWFADGARERFLGARAGEGWTQVRDILDVWFDSGSTHTFTLEDRPDLKWPADVYLEGSDQHRGWFHSSLLESCGTRGRAPYNAVVTHGFTMDEHGKKMSKSLGNTVTPQDVIKESGADILRLWVMTTDYWEDQRLGKSIIQTNIDAYRKLRNTIRWMLGTLAHDEGENVAYADLPELERLMLHRLTELDELVRSGYDTFDFKRIARALVDFMNVELSAFYFDIRKDALYCDAPSSIRRKAALQTVREIFVRLTTWLAPMLPFTMEEAWLDRYPQSVSIHAEQFRPTPAEWRDDVLAEKWRKVRAVRRVVTGALELERADKRIGSSLEAAPVVYIADKSLSDSLEGLDFAEICITSGISVSDAAAPEGAFTLGDVKGVAVVPERAKGEKCARSWRYTTDVGADPEFPEVSARDAAALRELQALGKL
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUB1_ASPFN
Sequence: MREVNFSIPNVNKASVNITTTLYDRRALDCTSTLPLINSLNHLAYLTTSSARIRDILTVDGGIERLVCILKEGRSRDLMEMWKWSLAFQCVVNIGVRGSESVRTRVVEADMVPVIATILDNYIKVVDKARARADSENQRHSSRHHPKAAPAAGDVTGRPSFPDQSSNSEQRTSRRQAPPPSIEIPAFLHQNTNAPDTNAMDVTSSPRAPMTSPPERSTFGQEAHIHRSHDGRHLHTGHRHRAMQPLATALPPMDTADGFGLRPVRDTERLPSMLPTLHNGITSQPDSPTTPNGPVQPRSHAQTSAARQRPTLRQQQSASGDSDDGNGEGSTLGDNAGSAETSEPIVGLQNEMEIDEVSDRQTMIDGVSNSHDLTVTDPSESQEAETFNISHRSTVDGSIINNDTTQTNTALGLSPTQAANNANSPALVPSPYTLYFRDRSAVPQNVLTTMPRDEDVLMSLQLLAYVSKYCNLRSYFQHSHLVPKLKVDRELQMLEEGASPIEPPEEEEEYMLPDDVNIFPLVEKFTVRHHSKDMQYWACVVMRNLCRKDESRGGIRQCAYYKCGKWEEFQRQFAKCRRCRRTKYCSKDCQKAAWVYHRHWCHTTP
What is the function of this protein?
Involved in determination of the onset of polarized growth and morphogenesis.  Plays a role in the regulation of branching in hyphae and spore formation (By similarity).
What are the official names of this protein?
MYND-type zinc finger protein samB, Suppressor of anucleate metulae protein B.
What is the protein family that this protein belongs to?
Belongs to the MUB1/samB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZAPD_BURP6
Sequence: MILYEYPFNERIRTLLRLEDLFERFTFFVAQEDAREHHVALTTLFEISEVAGRADLKSDLMKELERQRQTLAPFRGNPGIEQNALEAVLGEIEQTLANLAQMQGKTGQHLIDNEWLASIRSRAVIPGGTCKFDLPSYYAWQQWPAEQRRHDIAKWAMPLLPLRDAAMIVLRLARESGQASKVMAMQGSYQQMLSGRTYQLMQVRVPPELRVIPEASANKYMLWVRFTAQDGDVRPRAVDIDVPFQLTLCNL
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: PAM17_YEAST
Sequence: MFTSAIRLSSQRLFASQPSVTAAALRSTATTLPLRSYSQPASLQDSSILTWSDFFKLRKQQRRINVGSSLFTALLGCNVSWAYLSTMEIDPTQMLFGFDPLTVISAGIIASGALGYLLGPIVGSQVFKLSHNQQLAQFNNKNKEFLKHIINNRVDASSQSFSNPVPDYYGEKIGSLKEYKQWLRDCHAYAKKAKEFL
What is the function of this protein?
Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.  In the complex, it is required to organize PAM16-PAM18 (TIM16-TIM14) heterodimer.
What are the official names of this protein?
Presequence translocated-associated motor subunit PAM17, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PAM17 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NXF1_CAEEL
Sequence: MERDGCFGNCWLRRWEKSDMNRKGFGGHRDAKQLSRTKNRFARLDPDTQSRYEDDDEPAVPVRASLTSASSRGRGGSSRGFGQSAASIANTGVRNADIVYKCRATGAAKKVDAKWLIKQLNQIIENFKPLLWTDNARGDFEWYVRDEDTASTIRANNRRVVHKESGTRVEFYTSKVPAPWMKLKREEIEIIHRVVDKRHNAENRVLDLSNFHEDEEFKAKDMMMNLTKGNVMLTVLDHIDDKYGNIVALSLSNNRIRHLDYASALVSIAKFVMELDLSHNHISTEKELEKFAGLPVERFFFEGNPVVESFTQRAAYISYIHQSFPRCNMLDGVEVQPLVVGPDLDIHDAMPFRAGYYPNPQIRVLVEQFVTSYFDFYDGPDGQRTRRNLHNAYDADASTFSLTIEHLRGSSHARHHNDECFAQYAGVSHNVLKQERFARHRASRSARGAMDIAVALSKLPTSSHMRDTFIVDVFLQSNDLLGFTVQGLFCDGDLTQTPSPSFFSRSFLVSPRENDSVAVISDQLFITVASLDRLEKFKKLYDQSIANGAAVEQVSAVQIAQIGVNGMGFDGAPALPIREEMIKAMCQFSGMIPPFSEKCLADCAWNFDFACQKFNEIKSSVPAEAFAH
What is the function of this protein?
Involved in RNA export from the nucleus to the cytoplasm.
What are the official names of this protein?
Nuclear RNA export factor 1.
What is the protein family that this protein belongs to?
Belongs to the NXF family.
What are the subcellular locations of this protein?
Nucleus. Note=Shuttle protein that accumulates in the nucleoplasm and at the nuclear rim.
Protein: MNTH_LEVBA
Sequence: MKNHETDTKTKHHMIESTGSGQKSLDEVNGTVEVPQNAGFWRTLMAYTGPGALIAVGYMDPGNWITSIAGGAQYKYTLLTVVLLSSLVAMLLQAMSARLGIVTGKDLAQLTREHTGKRTGFALWIITELAIMATDIAEIIGSAIALKLLFGFPLIVGIIITAMDVLVLLVLMKLGFRKIEAIVATLVAVILFVFLYEVILAQPHMGEVLKGYLPSSTVVTNHGMLYLSLGIVGATVMPHDLYLGSSISQTRSFDRKNRKSVAQAIKFTTIDSNIQLTLAFVVNSLLLILGAALFFGTNSDLGRFVDLFNALSDSQIVGAIASPMLSMLFALALLSSGQSSTITGTLAGQIIMEGFINLKMPLWAQRLITRLLSVTPVIIFAIIYHGNEAKIEDLLTFSQVFLSIALPFAMIPLVIFTSSKKLMGEFANRTWSKILGWIIAVILIILNIYLILNTLHIVQ
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPA_BRUSI
Sequence: MDIRAAEISAILKEQIKNFGKEAEVSEVGQVLSVGDGIARVYGLDNVQAGEMVEFPGGIRGMALNLESDNVGVVIFGADRDIKEGDVVKRTGAIVDVPVGPELLGRVVDALGNPIDGKGPIKAKERRRVDVKAPGIIPRKSVHEPMSTGLKAIDALIPVGRGQRELVIGDRQTGKTAIILDTFLNQKPIHDNGPDKDKLYCVYVAVGQKRSTVAQFVKVLEERGALEYSIVVAATASDPAPMQYLAPFAGCAMGEYFRDNGQHALIGYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDENGAGSLTALPVIETQGNDVSAFIPTNVISITDGQIFLETNLFYQGIRPAVNVGLSVSRVGSSAQIKAMKQVAGSIKGELAQYREMAAFAQFGSDLDAATQRLLNRGARLTELLKQPQFSPLKTEEQVAVIYAGVNGYLDKLAVNQVGKFEEGLLASLRTEHKDVLEGIRNEKALTDDLKAKLKAAIDAFAKSFA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PDXT_SACS2
Sequence: MKIGIIAYQGSFEEHFLQLKRAFDKLSLNGEIISIKIPKDLKGVDGVIIPGGESTTIGLVAKRLGLLDELKEKITSGLPVLGTCAGAIMLAKEVSDAKVGKTSQPLIGTMNISVIRNYYGRQKESFEAIVDLSKIGKDKAHVVFIRAPAIAKVWGKAQSLAELNGVTVFAEENNMLATTFHPELSDTTSIHEYFLHLVKG
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: ARALB_ARAEL
Sequence: ANPICPKIPNPTIRISGRNDLCVDVK
What is the function of this protein?
Lectin specific for galactose (Gal) and its derivatives.  Induces apoptosis.  Has cytotoxic activity against several human cancer cell lines.  Is less cytotoxic to normal human cells.
What are the official names of this protein?
Aralin B chain.
Protein: RL18A_METMA
Sequence: MVMMKSFIVKGKFKAGNSWEKFTKKIESQNEKNATDKTYSIFGSKHGVKRSQIQIESVAEE
What are the official names of this protein?
50S ribosomal protein L18Ae, 50S ribosomal protein L20e, 50S ribosomal protein LX.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL20 family.
Protein: FETCB_GLOBR
Sequence: MNSLVALVLLGQMIGSTLSHHLQSHVDCNGEDAEKWADMAVHYINEHNLHGYKQVFNVINEIHVLPRRPRGKIIILELKLLETECHVLDPTPVENCTVRPPHYHAVEGDCDVKILHDEGVDKVIGAKCHSDPDSVEDVRRNCPKCPILLPLSDPHVVDSVEYVLNKHNEKLSGHVYEVLEISRGQHKYEPEAFYVEFAIVEVNCTAQEAHDDHHHCHPNTAGENHIGFCRATVFRSHASLEKPKDEQFESDCVIFDVKEGHAHSHLIEHHIGNYNTSPGHNNTVLNLAHSHNHTSASHESHSHEHVAEVPVAVAKREVPTNTPHDHTHPVKLCPGKVHHFKL
What is the function of this protein?
Potent inhibitor of hemorrhagic activity but also proteolytic activities.  Inhibition occurs by formation of a non-covalent complex between this protein and the proteinases at their metalloproteinase domains (By similarity).
What are the official names of this protein?
Antihemorrhagic factor cHLP-B, Chinese mamushi HSF-like protein B.
What is the protein family that this protein belongs to?
Belongs to the fetuin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MKAR_AJECN
Sequence: MDRLLQFRFESAPGWQSNVALFLLSIGGLFTACKLFSFCRALLSIFVLPGQKLSKFGPKGSWALVTGASDGIGKEYSLQLARAGYNILLVSRTTSKLAAVADEIKSKSPTVQTKVFAMDFFKNNDGDYENLKLLIQDLDISILVNNVGRSHSIPTPFVLTPLEELENIIMINCTGTLRITQLVAPGMMQRKRGLILTMASFAGMIPTPLLATYCGSKAFLQYWSIALGAELQPYGVQVELVQSHLVTSAMSKIRRPTVTVPIPRDLVRAVLSKIGRGSGLSAYAYTSVPYWSHGLMAYALTQVLGHMGKFVLGYNKALHESIRKRALRKAEREKNKKST
What is the function of this protein?
Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate.  Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation.  VLCFAs serve as precursors for ceramide and sphingolipids.
What are the official names of this protein?
Very-long-chain 3-oxoacyl-CoA reductase, 3-ketoacyl-CoA reductase, 3-ketoreductase, KAR, Microsomal beta-keto-reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: DER_CAMJE
Sequence: MQSIILIGKPNVGKSSLFNRMARQRIAITSDISGTTRDTNKTQIHIHSKKAMLIDSGGLDESDELFKNVKKNTLKVAKESDIILYLVDGKLAPDDEDRQFFYSLKKLGKPIALVINKVDNKKDEERAWEFANFGVKEIFNLSVTHNVGLDELYEWLEKFLHEEFLIPDEEENLEDFLEYYEEGKEFQFKEVDQNHIRVGIVGRVNVGKSSLLNALVKQERSVVSSIAGTTIDPVNESVVHKDKVIEFVDTAGIRKRGKIQGLERFALNRTEKILSHSQIALLVLDAHEGFNELDERIAGLVAKHYLGVIIVLNKWDKSEMDFDKTVKELRLDRFKFLAYAPVISVSALSGKRVHVLLDKILQIFENFTQKIQTSKLNTLIENATRAHPLPHDYGKLVKIYYAVQYDLAPPKIALIMNRPKALHFSYKRYLQNQIRKEFNFEGVPLVIASRKKGSKENDES
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: PCDB9_HUMAN
Sequence: MKTRGFSFPRQRQVLFLFLFWGVSLAGSGFGRYSVTEETEKGSFVVNLAKDLGLAEGELAARGTRVVSDDNKQYLLLDSHTGNLLTNEKLDREKLCGPKEPCMLYFQILMDDPFQIYRAELRVRDINDHSPVFRHKEMVLKISENTAEGTAFRLERAQDPDEGHNSIQNYTISSNSFFHIKISGSDEGMIYPELVLDKALDREEQEELSLTLTALDGGSPSRSGTSTIRIVVLDVNDNVPQFAQALYETQAPENSPVGSLIVKVSAGDADSGVNAEVSYSFFDASEDILTTFQINPFSGEIFLRELLDYELVNSYKINIQAMDGGGLSARCTVLIKVLDSNDNPPELIISSLSNSVAENSPGIVLAVFKIKDRDSGENGKTICYVQDNLPFFLKPSVDNFYILMTEGALDRESKAEYNITITVTDLGTPRLKTEHSITLQVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDRDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFDFRVGASDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHVLLVDGFSQPYLPLPEAAPAQAQADLLTVYLVVALASVSSLFLLSVLLFVAVRLCRRSRAASVGRCSVPEGPFPGHLVDVSGTGTLFQSYQYEVCLTGGSETGEFKFLKPITPHLPPHRGGKEIEENSTLPNSFGFNY
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin beta-9, PCDH-beta-9, Protocadherin-3H.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.