PharMolix/UniProtQA huggingface dataset:
Protein: PYRF_ALKCK
Sequence: MNRPFFIALDFDEHAKRQRFLESFAAETLDVKIGMELFYREGLSVVHELKEAGYRLFLDLKLHDIPNTVGRTMRALAELDVDVVNVHAAGGKAMMEAALEGLDAGTRAGKQRPKLIAVTQLTSTDSRMLAEELLIDKAMDEVVVRYAQLAQESGLDGVVCSAHEVPLIRAACSDRFLTVTPGIRRQVDQVGDQVRVVTPGEAKALGSWAIVVGRSITAAADPLAVYREMNQDWKGATEH
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RHAM_SINMW
Sequence: MEKYAFRMRLHPGKAAEYQARHDAIRPELVALLKDAGISDYSIHLDEENDLLFGVLWRSDDHKMADLPSHPVMRKWWAHMADIMETHADNEPVAAPLKTVFHLR
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_SHEFN
Sequence: MAAKIRREDEVIILAGKDKGSRGKVSQVLPTGKLIVEGFNLVKKHQKPNPQLGVAGGVIEKEAPMQASNVAIFNQATGKADRVGFRFEDGKKVRFFKSNSELVK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: YVN2_AZOVI
Sequence: MSNPPLDTEENATTLAITPIPAESLPLVRETVERLRPGVQRDGGDLELVAVQDNIVRLRLKGACVGCAMSAQTLGGVRRELVKVLDNPSVRVLPAP
What are the official names of this protein?
Uncharacterized 10.3 kDa protein in vnfA 5'region.
What is the protein family that this protein belongs to?
Belongs to the NifU family.
Protein: TIG_SYNC1
Sequence: MNVKVEDISSIKKKLSFEISVEAVDTEFSNEYKKLSKTAKIPGFRKGKVPRSVLERQYAGHVEGQVFERLVNETFFKALVDEKINAVSAPEVVDNGPLKPGQAFTYEAEVEVRPDVEAKDYIGLDLKKENFAVEDQDVEDRLQDMLKSRAKVEVSEREVAQAGDIAVIDFEGFVDGEAFAGGKAEGHELELGSNSFIPGFEDQVVGMECGQDKDIEVAFPEDYGNEELAGKPAVFKVRLNQIKERVLPALDEEFAKEAGLESVEDLKIKIRESIEGQERDRIEKDFRERMTDALIEANEFEVPEGMIDSQIDYMLKNLQNRMQAQGMRLEDMGINAESFRQIYREVAAKQVKASLILEAIALQENLKVEEDEIKDKLEEIVETSGAPKEAVMNYYSNDESRRGLVSQMAEEKVVAFLTGKAKIEMVDKEALENAKMTEE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: MIA40_ASPFU
Sequence: MFRPATRILLRAPGVAARGPVSRRLISTAPPDAKSRSWKSTIVRLGLAAGAVYYYNTSSVFAEQPSLSFLSKQSTPDSSDETQLPTIDSIKPRIREERQAESKAVSQPDAQPTQHEALSASEAALKSPQELEDEAGQEAAFNPETGEINWDCPCLGGMAHGPCGEEFKAAFSCFVYSTEEPKGMDCIDKFKGMQECFRRYPDVYGAELEDDDEADAAAATAAGVSEPSEQPASPTVSAPTAEIDASSDSEGKEGRAKDVHAQVKSEVAEKAEQAESDDLVPKAWHDTEGTKAQQTEK
What is the function of this protein?
Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS).  Forms a redox cycle with ERV1 that involves a disulfide relay system.  Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria.  The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS (By similarity).
What are the official names of this protein?
Mitochondrial intermembrane space import and assembly protein 40, Mitochondrial import inner membrane translocase TIM40.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass type II membrane protein; Intermembrane side.
Protein: ARGB_MYCTA
Sequence: MSRIEALPTHIKAQVLAEALPWLKQLHGKVVVVKYGGNAMTDDTLRRAFAADMAFLRNCGIHPVVVHGGGPQITAMLRRLGIEGDFKGGFRVTTPEVLDVARMVLFGQVGRELVNLINAHGPYAVGITGEDAQLFTAVRRSVTVDGVATDIGLVGDVDQVNTAAMLDLVAAGRIPVVSTLAPDADGVVHNINADTAAAAVAEALGAEKLLMLTDIDGLYTRWPDRDSLVSEIDTGTLAQLLPTLESGMVPKVEACLRAVIGGVPSAHIIDGRVTHCVLVELFTDAGTGTKVVRG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_ACIC5
Sequence: MSTYFPSSHDISRKWFVVDASGKTLGRLATEAARVLSGKNSPKYTPFMDMGDHVIVINAEKIRLTGLKSQQKVYRRYTGFPGGLREESFTRLLQRKPEKIVEEAIKGMLPKTKLGRKMASKLNVYKGDQHPHAAQQPQPLEINA
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: GOLM2_CHICK
Sequence: MVGFGANRRGGRLPSFLLAALLLVIAVLAFNCWNAASRQAVLREELAELQSQAKRTEVARGRLEKRNSDLLGRVDSHRKQLEQKEADYSQLSSQLQARDGQVKRCEDSRVKLQNNISYQMADIHRLKEQLAELRQEFIRQEDQLHEYKKNNTYLTRRLEYDSLQCGQQIKEMRIQHEENIKKLMDQIVREQKATQRIQSSKDAEVNPNGDNQPISKTVPEMEVKNAENNELPSDRVVNGKEKVKPGGDAGMPEIEDNDPAKAEDTPTAPRSDNHHQADVNLPTEQPHAPNLAPGLHGDSDGNADIAKEIPPNSLQHLNFGENMDSQNENKIEADHLKLQKGRAVGLQKMKQNDEERDLQNDLVDYSKPRFGDGVL
What are the official names of this protein?
Protein GOLM2, Cancer susceptibility candidate gene 4 protein homolog, CASC4, Golgi membrane protein 2.
What is the protein family that this protein belongs to?
Belongs to the GOLM family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: RL31B_NEIMB
Sequence: MKPNIHPDNYRTVLFFDSSANEGWLIRSCAETHGKTMVWTDGKEYPLFSLDTSSASHPVYTGKQRNVNTEGRASKFNQRFQSVMSSFRKDK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: DNLJ_TREDE
Sequence: MAKEKRILDLEKTIKKHQDLYYNAQPEISDAEFDALWDELKALDPQNKLFFTVPLESTEGFAKSEHIIPMGSQEKAADPPSFEAWALKMPFKEYIVQYKMDGASLELQYEEGHFVRAVTRGDGKIGDDITENVLKMKGLIKDITVNAGPAYGTKPFSGGIRCEVIMLRSIHQKYFKDKANCRNAANGLMKKKNGELCEHLNLFAYDAVQGSIGRPFTGDAPFKTESEKLVWLKKAGFNCVEVKYCKSIAEVIEYRAHVMDIRPSLDYDIDGLVIKNDTIDPEDMKRARPEKQIAFKFSLEEAVTVLKEIEWSESGATYTPIALIEPVRLAGTTVKRASLANPNIIKALNLKIGSRVVVTKRGEIIPKIEALAENPPNVKEIEYPDTCSVCGSPLTNEGTRLYCPNMSCPKLIHHRIEKWISVLDIRDFGITLIKRLFEMGRVNSITDLYTLTVEELAAIDRMGKLSAEKVYKALHSKKEISLTEFIAGFDIEGIGETMVEKLEEAGFNDLNELLGASEADFANVYQFGQVLSHTLVTNLSILKDEMTGLIDKGYIKIKPPLTSEEGAVLKGLSFCFTGELNTMKRAQAEALVKEKGGTVKSSVVKGLSYLVTNTPDSGSSKNKKAQELGTAIITEEAFLNLIGKV
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RL6_PSEPG
Sequence: MSRVAKNPVKLPSGVEVKFAGQQLSVKGAKGTLELNVHSSVEVTEESGELRFVARNGDQQARAMAGTTRALVNNMVQGVSQGFERKLQLVGVGYKAQAKGTVLNLALGFSHPVDYELPAGITAETPSQTDILIKGIDKQLVGQVAAEIRDFRPPEPYKGKGVRYADEVVRRKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RSXA_ECO81
Sequence: MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLATTFVMTLASICAWLIDTWILIPLNLIYLRTLAFILVIAVVVQFTEMVVRKTSPVLYRLLGIFLPLITTNCAVLGVALLNINLGHNFLQSALYGFSAAVGFSLVMVLFAAIRERLAVADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rsx electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS4_CLOBA
Sequence: MIILPAIDIIDGQAVRLYQGDYNKKEVVANDIFNIAKEFECLGAEYIHLVDLDGAKSGYCVNEKIILKLAQTVDVPIEVGGGIRNFETIEKLIENGISRVILGTIAMEDEGLLKKAIECYGEKISVGIDCKNGYVYGRGWLAESKLNYLDFAKNMESLGVKSIIVTDISKDGTLEGPNFDMLMKLKKLVNIDITASGGIRDIENIKELKNIDIYGAITGKAIYSGNLSLKEAIDITR
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_ANADE
Sequence: MAGNRSIITLECKTCKERNYTTTKNKKKTQDKLTLSKYCPRCRKHVEHKETK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: FAR1_WUCBA
Sequence: MYHRLILLALIGTTMANVIPFSMSTIPEEYKEFIPEEVRNFYKDLTVEDKEILRELASKHATFANEDAALEALKAKSDNLYKNAVELRNFVKAKIDSLKPDAKTFVDEIIAKARSLRSDDGHKLDTEKIKQAARDIIAKYQALSEETKEELKVTFPAIAKIIGNEKLKRNASTFLQKN
What is the function of this protein?
Binds retinol and different fatty acids.
What are the official names of this protein?
Fatty-acid and retinol-binding protein 1, Wb-FAR-1.
What is the protein family that this protein belongs to?
Belongs to the fatty-acid and retinol-binding protein (FARBP) family.
What are the subcellular locations of this protein?
Secreted.
Protein: DART_ECO27
Sequence: MAYDYSASLNPQKALIWRIVHRDNIPWILDNGLHCGNSLVQAENWINIGNPELIGKRAGHPVPVGTGGTLHDYVPFYFTPFSPMLMNIHSGRGGIKRRPNEEIVILVSNLRNVAAHDVPFVFTDSHAYYNWTNYYTSLNSLDQIDWPILQARDFRRDPDDPAKFERYQAEALIWQHCPISLLDGIICYSEEVRLQLEQWLFQRNLTMSVHTRSGWYFS
What is the function of this protein?
Toxic component of a hybrid type II/IV toxin-antitoxin (TA) system.  ADP-ribosylates ssDNA in the sequence TTT/TCT.  Its toxic effect is neutralized by cognate antitoxin DarG (PubMed:32023456).  May target ssDNA loops during DNA replication, probably modifies thymidine (Probable).  Wild-type protein cannot be expressed at low levels in the absence of its cognate antitoxin, but a mutant protein (G49D) can be expressed, which slows growth, rapidly inhibits DNA replication, and induces RecA expression and the SOS response (PubMed:32023456).  The slow growth phenotype can be suppressed by cognate antitoxin DarG.  Has no activity on dsDNA in vitro (PubMed:32023456).  In vivo ADP-ribosylates genomic DNA (gDNA) (PubMed:34408320).  Genetic data strongly suggests ADP-ribosylation by DarT probably generates ssDNA gaps that are repaired by the RecFOR-mediated homologous recombination pathway (RuvAB, RecG) and resolved by RuvC.  In some cases these gaps probably migrate into dsDNA, where they are resolved by nucleotide excision repair (NER) detected by UvrAB, excised by UvrC, removed by UvrD, and repaired by Pol I and ligase.  Other pathways may also be involved in ADP-ribosylation removal from DNA (Probable).
What are the official names of this protein?
DNA ADP-ribosyl transferase, DarT, Toxin DarT.
What is the protein family that this protein belongs to?
Belongs to the DarT ADP-ribosyltransferase family.
Protein: FOLD_ACIAC
Sequence: MTAQLIDGNALSRQLRADVARRAALLKERGTTPGLAVVLVGDNPASQVYVRNKVKACEESGLHSVLEKYDAAMSEAELLARVDALNNDPSIHGILVQLPLPAHIDAQKVIEAISPAKDVDGFHIASAGALMTGMPGFWPCTPYGCMKMLEHIGYDLRGKHAVVIGRSNIVGKPMALMLLAKDATVTVCHSRTADLKAQTLQADVIVAAVGRRNVLTADMVKPGAVVIDVGMNRNDEGRLCGDVDFDGVREVAGHITPVPGGVGPMTITMLLVNTLEAAERAAG
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: NU4M_BOSIN
Sequence: MLKYIIPTIMLMPLTWLSKNSMIWVNSTAHSLLISFTSLLLMNQFGDNSLNFSLVFFSDSLSTPLLILTMWLLPLMLMASQHHLSKENLTRKKLFITMLISLQLFLIMTFTAMELILFYILFEATLVPTLIIITRWGNQTERLNAGLYFLFYTLAGSLPLLVALIYIQNTVGSLNFLMLQYWVQPVHNSWSNVFMWLACMMAFMVKMPLYGLHLWLPKAHVEAPIAGSMVLAAVLLKLGGYGMLRITLILNPMTDFMAYPFIMLSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVIVAILIQTPWSYMGATALMIAHGLTSSMLFCLANSNYERIHSRTMILARGLQTLLPLMATWWLLASLTNLALPPTINLIGELFVVMSTFSWSNITIILMGVNMVITALYSLYMLIMTQRGKYTYHINNISPSFTRENALMSLHILPLLLLTLNPKIILGPLY
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ZDH15_MOUSE
Sequence: MRRGWKMALSGGLRCCRRVLSWVPVLVIVLVVLWSYYAYVFELCLVTVLSPAEKVIYLILYHAIFVFFAWTYWKSIFTLPQQPNQKFHLSYTDKERYKNEERPEVQKQMLVDMAKKLPVYTRTGSGAVRFCDRCHLIKPDRCHHCSVCAMCVLKMDHHCPWVNNCIGFSNYKFFLQFLAYSVLYCLYIATTVFSYFIKYWRGELPSVRSKFHVLFLLFVACMFFVSLVILFGYHCWLVSRNKTTLEAFCTPVFTSGPEKNGFNLGFIKNIQQVFGDNKKFWLIPIGSSPGDGHSFPMRSMNESQNPLLANEEPWEDNEDDSRDYPEGSSSLAVESET
What is the function of this protein?
Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates (PubMed:15603741, PubMed:17012030, PubMed:28167757).  Has no stringent fatty acid selectivity and in addition to palmitate can also transfer onto target proteins myristate from tetradecanoyl-CoA and stearate from octadecanoyl-CoA (Probable).  Palmitoylates IGF2R and SORT1, promoting their partitioning to an endosomal membrane subdomain where they can interact with the retromer cargo-selective complex (By similarity).  Thereby, regulates retrograde transport from endosomes to the Golgi apparatus of these lysosomal sorting receptors and plays a role in trafficking of lysosomal proteins (By similarity).  In the nervous system, catalyzes the palmitoylation of DLG4/PSD95 and regulates its synaptic clustering and function in synaptogenesis (PubMed:15603741).  Could be involved in the differentiation of dopaminergic neurons and the development of the diencephalon (By similarity).  Could also catalyze the palmitoylation of GAP43 (PubMed:15603741, PubMed:17012030).  Could also palmitoylate DNAJC5 and regulate its localization to the Golgi membrane (PubMed:18596047).  Could also palmitoylate FYN as shown in vitro (By similarity).
What are the official names of this protein?
Palmitoyltransferase ZDHHC15, Acyltransferase ZDHHC15, Zinc finger DHHC domain-containing protein 15, DHHC-15.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Postsynaptic density.
Protein: CDC31_SCHPO
Sequence: MFANARAKRRSRASSPTPARLGGYAPLRVEITEEQRQDINEAFKLFDSDKDNAIDYHELRAAMRALGFNAEKSEVLKILRDFDKTGKGYLQMEDFVRVMTEKIVERDPLEEIKRAFELFDDDETGKISLRNLRRVAKELNENIDDQELEAMIEEFDLDQDGEINEQEFIAIMMDEA
What is the function of this protein?
Required for the proper coordination between exit from mitosis and the initiation of septation.  Has a role in bipolar spindle formation during spindle pole body (SPB) duplication.  Required for the localization of sad1 to the SPB (PubMed:12857865).
What are the official names of this protein?
Cell division control protein 31.
What is the protein family that this protein belongs to?
Belongs to the centrin family.
What are the subcellular locations of this protein?
Nucleus. Note=Associates with the half-bridge structure of the SPB.
Protein: TDH_SALG2
Sequence: MKALSKLKAEEGIWMTDVPEPEVGHNDLLIKIRKTAICGTDVHIYNWDDWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGGRTHLCRNTTGVGVNRPGCFAEYLVIPALNAFKIPDNISDDLASIFDPFGNAVHTALSFDLVGEDVLVSGAGPIGVMAAAVAKHVGARHVVITDVNEYRLELARKMGVTRAVNVAKESLNDVMAELGMTEGFDVGLEMSGAPPAFCTMLDTMNHGGRIAMLGIPPSDMSIDWTKVIFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSIDDFQKGFDAMRSGQSGKVILSWD
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DSD1_CHICK
Sequence: MWLGALLDTLPTPALTIDRTTAHRNAERMRERCRALGVRLRPHVKTHKTLEGGLLATGGTRRGIAVSTLAEARFFADGGFDDILLAYPVPTARLEECAGLARRLDAFHVLLDRPEALASLRQRPLGHGKRWLVWLKLDCGNGRAGVRPTDPAALELAQAIANDAPEEVTLVGVYAHCGNTYGCSGADTIQAIARTTTNAVLSFVAALRQAGVPCPQASIGSTPSCSHPIPEMSQLTELHPGNYIFYDLQQTQLGSCQPQDVAIRVLTRVIGHYAHRGQLLVDCGWAALSLHGAGAGQGPQGCAAIDGHPELRLVGLTQEHGLLEHAGGQMDFGRFPVGSVLALIPYHACATAAMHPVYYVHEEGKVVALWHPVRGW
What is the function of this protein?
Catalyzes the conversion of D-serine, an allosteric activator of the N-methyl-D-aspartate (NMDA) receptor for L-glutamate, to pyruvate and ammonia.
What are the official names of this protein?
D-serine dehydratase.
What is the protein family that this protein belongs to?
Belongs to the DSD1 family.
Protein: ACTP1_ACTVL
Sequence: MRHFVVFLYMFLALSIPTAFAKKHIVTKKGNHQDITNDNEGENAEKKSAAVAGAVIAGGELALKILTKILDEIGKIDRKIAIGVDNESGLKWTALNTYYKSGASDVTLPYEVENSKALLYTARKSKGPVARGAVGVLAYKMSSGNTLAVMFSVPFDYNLYSNWWNVKIYDGEKKADEKMYNELYNNNNPIKPSTWEKRDLGKDGLKLRGFMTSNGDAKLVIHIEKS
What is the function of this protein?
Pore-forming protein that forms cations-selective hydrophilic pores of around 1 nm and causes cytolysis.  Pore formation is a multi-step process that involves specific recognition of membrane sphingomyelin (but neither cholesterol nor phosphatidylcholine) using aromatic rich region and adjacent phosphocholine (POC) binding site, firm binding to the membrane (mainly driven by hydrophobic interactions) accompanied by the transfer of the N-terminal region to the lipid-water interface and finally pore formation after oligomerization of monomers.
What are the official names of this protein?
DELTA-thalatoxin-Avl1a, DELTA-TATX-Avl1a, Cytolysin Avt-I, Hemolytic toxin Avt-1.
What is the protein family that this protein belongs to?
Belongs to the actinoporin family. Sea anemone subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst. Target cell membrane. Note=Forms an alpha-helical membrane channel in the prey.
Protein: SYT_ARTS2
Sequence: MSDAQQITLIVDGEETKVTTGTTGAELFFERRDVVVARVNGELKDLDQPLPEGADIEGVTIDSPDGLNVLRHSTAHVMAQAVQQLRPDAKLGIGPYITDGFYFDFDVAEPFTPEDLKALEKMMLKIINQNQKFVRRVVSEDEAREAMKNEPYKLELLGKKNNAADAGEGVNVEVGAGDITIYDNVDRKSGDSVWCDLCRGPHLPNTKLISNAFALTRSSAAYWLGNQNNQQLQRIYGTAWPTKDALKAYQERIAEAERRDHRKLGAELDLFSFPDELGSGLPVFHPKGGIIRKAMEDYSRQRHVDAGYDFVYTPHITKGHLYEVSGHLDWYKEGMFPAMHIDAELNEDGTVRKPGQDYYLKPMNCPMHNLIFRSRGRSYRELPLRLFEFGSVYRYEKSGVVHGLTRVRGMTQDDAHIYCTREQMKDELTTTLNFVLGLLKDYGLDDFYLELSTKNEDKFVGDDATWDEATRTLAEVAEASGLELIPDPGGAAFYGPKISVQAKDALGRTWQMSTIQLDFNLPERFELEFQAADGTRQRPVMIHRALFGSVERFMGVLTEHYAGAFPAWLAPVQVVGIPVAEAFNDYMFDVVDQLKAVGIRAEVDISSDRFPKKIRTASKDKIPFVLIAGGEDAEAGAVSFRFRDGSQDNGVPVAEAVQRIVEAVRNRTS
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAO6_SCHPO
Sequence: MGRPLTEVKYLLINSAPVILGYALQNSLQTSSVIVTGRLGPSELSVAAFAYMFAMSTGWLIALGGTTAFDTLGSNLWGAGKKQELGILLQTGFIVLSILYLPICLVWWYSKPILIFLHQTPELAEASQKFLRYLIPGGLGYVCFELLKKFLQTQEITRAGSYILLVTSPLNVALNFLLVHYYGLGLKGAPLATGLSYWLSFILLTQYAKYVKGAEAWNGWNKRCLENFGPFVKLSLLGIVMVGTEWWAFEIVALVAGKLGAVPLAAQSVIMTTDQLLNTIPFGLGIITSNRVAYYLGAGLPDNASLTAKVAAIVGVAVGSVIMITMIAVRNIYGRIFTNDPDVIQLVALVMPLVAAFQISDSLNGTMGGALRGTGRQKVGAIVNITAYYLFALPLGIYLAFHGKGLVGLWIGQVIALSIVGILELKIVMATDWISQSRKAISRFGDSSELTALLN
What are the official names of this protein?
Uncharacterized transporter C11D3.06.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYGA_HALH5
Sequence: MNVQTMILTLQEYWSKQNCILLQAYDTEKGAGTMSPYTMLRTIGPEPWNVAYVEPSRRPADGRYGENPNRLYQHHQFQVIMKPSPTNIQELYLDSLRALGINPLEHDIRFVEDNWENPSLGCAGLGWEVWLDGMEITQFTYFQQVGGLEANPVSAEITYGLERLASYIQDKENVFDLEWVEGFTYGDIFTQPEYEHSKYTFEVSDSAMLFELFSTYEKEADRALEENLVFPAYDYVLKCSHTFNLLDARGAISVTERTGYIGRVRNLARKCAKKYYEEREKLGFPMLKNKEADHEQA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
Protein: PSAI_WELMI
Sequence: MENSNLFSFFVPLVGLVFSAIIMVLSFLYIQKDSVN
What is the function of this protein?
May help in the organization of the PsaL subunit.
What are the official names of this protein?
Photosystem I reaction center subunit VIII, PSI-I.
What is the protein family that this protein belongs to?
Belongs to the PsaI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: METQ_YERPE
Sequence: MSLKFKSIAAISALIGTLTLVGCGPTEKAPNHIKVGVIVGAEQQVAEVAQKVAKEKYGLDVELVTFNDYVLPNEALSKGDIDLNAFQHKPYLDQQIKDRGYKLVSVGNSFVYPIAGYSKKIKSLDELQPGSQVALPNDPTNLGRSLLLLQSVGLIKLKDGVGLLPTVLDVVENPKNLKLVELEAPQLPRSLDDQQIALAIINTTYASQIGLTPAKDGLFVEDKESPYVNLIVAREDNKDAENVKKFVQAYQSDEVYDAANKAFNGGAVKGW
What is the function of this protein?
This protein is a component of a D-methionine permease, a binding protein-dependent, ATP-driven transport system.
What are the official names of this protein?
D-methionine-binding lipoprotein MetQ.
What is the protein family that this protein belongs to?
Belongs to the NlpA lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: FAR2_RHOPR
Sequence: TYKKPPFNGSIF
What are the official names of this protein?
SIFamide related peptide, Rhopr-SIFa.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.