PharMolix/UniProtQA huggingface dataset:
Protein: ERP44_HUMAN
Sequence: MHPAVFLSLPDLRCSLLLLVTWVFTPVTTEITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSDPIQEIRDLAEITTLDRSKRNIIGYFEQKDSDNYRVFERVANILHDDCAFLSAFGDVSKPERYSGDNIIYKPPGHSAPDMVYLGAMTNFDVTYNWIQDKCVPLVREITFENGEELTEEGLPFLILFHMKEDTESLEIFQNEVARQLISEKGTINFLHADCDKFRHPLLHIQKTPADCPVIAIDSFRHMYVFGDFKDVLIPGKLKQFVFDLHSGKLHREFHHGPDPTDTAPGEQAQDVASSPPESSFQKLAPSEYRYTLLRDRDEL
What is the function of this protein?
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif (PubMed:11847130, PubMed:14517240).  Inhibits the calcium channel activity of ITPR1 (PubMed:15652484).  May have a role in the control of oxidative protein folding in the endoplasmic reticulum (PubMed:11847130, PubMed:29858230, PubMed:14517240).  Required to retain ERO1A and ERO1B in the endoplasmic reticulum (PubMed:11847130, PubMed:29858230).
What are the official names of this protein?
Endoplasmic reticulum resident protein 44, ER protein 44, ERp44, Thioredoxin domain-containing protein 4.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: GPI7_YEAST
Sequence: MNLKQFTCLSCAQLLAILLFIFAFFPRKIVLTGISKQDPDQDRDLQRDRPFQKLVFVIIDALRSDFLFDSQISHFNNVHQWLNTGEAWGYTSFANPPTVTLPRLKSITTGSTPSFIDLLLNVAQDIDSNDLSEHDSWLQQFIQHNNTIRFMGDDTWLKLFPQQWFDFADPTHSFFVSDFTQVDNNVTRNLPGKLFQEWAQWDVAILHYLGLDHIGHKDGPHSKFMAAKHQEMDSILKSIYDEVLEHEDDDDTLICVLGDHGMNELGNHGGSSAGETSAGLLFLSPKLAQFARPESQVNYTLPINASPDWNFQYLETVQQIDIVPTIAALFGMPIPMNSVGIIIPDFLQLLPNKLASMKENFMHLWKLSDHHGEVALDDFTAEDIYTKMYTIQETLTKSATNYNYPLLTLAFVGFLIITIIAIYVLLRYSGPDFWQLRVSSLSVLLVSIILGVSTFASSFIEEEHQLWWWIVTAFSAVPLFVYRLNVLIIVRWFIMMACVRSIKFWNNSGQKFIYSNVMSNLLNQNPSWKWCLNMLTFLVLIMASAGFQVLHFIVTTILVGLCFTYKISWEIVNGNQAEIPLFMHDLLAKIDFAPTESNLIVLARVFFQAWAIVVISRLVLTKLKVLNKNYLIKDMKVYITILLMFQTSSQNIGQFLVFQILESQIFYFFQNIPTASLTSTSKIYFSNLVSLILQNFTFFQFGGTNSISTIDLGNAYHGVSSDYNIYVVGILMSVANFAPAIYWSMLPWSINYASIPAQVKLQTFIRSKLPAFTYHCIFGTCLMTACVVLRFHLFIWSVFSPKLCYFLGWNFVMGLLNGWLPELALLCALD
What is the function of this protein?
Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers ethanolamine phosphate to the GPI second mannose.  Although not essential, addition of ethanolamine phosphate to the second mannose plays an important role in cell separation via the GPI-based modification of daughter-specific proteins.
What are the official names of this protein?
GPI ethanolamine phosphate transferase 2, Glycosylphosphatidylinositol-anchor biosynthesis protein 7, Local anestheticum-sensitive protein 21.
What is the protein family that this protein belongs to?
Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RS3_DEIDV
Sequence: MGNKINPNGFRLGITRGWNSRWYAGKKQYAGLLKEDEKIRKLVDKKLSAAGIARVEIERAGQQVNVIISAAKPGIVIGKGGDSIKQLRADIEKLVSAGTVAVNVAEIPNPNISAPLVALRIAEQIERRFAFRRAMKQAAQRVMESGARGVKVVLSGRLGGAEQARRETVREGRVPLHTLRADIDYGTALARTTYGILGIKVMVFTGEVIGGRTETIARPQRRNDERRPEGGDRANRRRPTARRRAGGE
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: PUR5_PROM1
Sequence: MDYKTAGVDVTAGRAFVERIKSCVEKTHKSEVIGGLGGFGGCIRIPKGFESPVLVSGTDGVGTKLELAQQYGCHFGVGIDLVAMCVNDVITNGARPLFFLDYIASGTLTPDALAEVIEGIAAGCCQSDCSLLGGETAEMPGFYPSGRYDLAGFCVGIVENHHLIDGTKINCGDQIIGIKSNGVHSNGFSLVRKVLSMANVDENTLYGKDKRNLIQSLLEPTAIYVQLVEKLLRENLPIHGMTHITGGGLPENLPRIFPSGLLPHIDITTWEITEIFNWLQNAGDIPEIDLWNTFNMGIGFCLIVPKNEVNSALEICMKNDFEAWNIGQVVESQNNSKHSGILGIPS
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG01_EHV1V
Sequence: MRPEGVSRGRASSVSISMCPPPPNGARRASLGCAPPLNSRPVCCAPSSVSLSSSSSRRSMPSLGSSRSSSLPSTGSLRSITRDPERLPSRPPSYTAINPECLLERGAERPRAWTASVMTAPPSYSEALCQAPPAYELVPELSYHPTQDPRGVYSSRSDPHQTSRRRQNPICIFIIVVATMLLILGLLLTITLSSLTNGKKEK
What are the official names of this protein?
Uncharacterized gene 1 protein.
Protein: KEFB_ECOSM
Sequence: MEGSDFLLAGVLFLFAAVAAVPLASRLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSKLWQLRRSIFGVGAAQVLLSAALLAGLLMLTHFSWQAAVVGGIGLAMSSTAMALQLMRDKRMNRSESGQLGFSVLLFQDLAVIPALALVPLLAGSADEHFDWMKIGMKVLAFVGMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLGSALFMDALGLSMALGTFIAGVLLAESEYRHELETAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVVISVVVLVAVKILVLYLLARLYGVRSSERMQFAGVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKLVDKWLSRQFNGPEEEDEKPWVNDDKPQVIVVGFGRFGQVIGRLLMANKMRITVLERDISAVNLMRKYGYKVYYGDATQVDLLRSAGAEAAESIVITCNEPEDTMKLVEICQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVTLGMHPHQAQRAQLHFRRLDMRMLRELIPMHADTVQISRAREARRELEEIFQREMQQERRQLDGWDEFE
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefB, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROC_BLOPB
Sequence: MAGNSIGQFFRVTTFGESHGSALGGIIDGVPPSLPLTEKDLQYDLDRRRPGSSRYTSQRSELDTVEILSGVFNGKTTGTSIGLLIKNTDHRPQDYEKIKNLYRPGHADYTYEKKYGFRDYRGGGRSSARETAVRVAAGAVAKKYLFNKKNIKIRGFLAQMGDVHCNLKDWRQVNNNPFFCPDLEKLTALDTLINNLQKSGDSIGAKITVIAENIPIGLGEPVFDRLDADLAHALMSINAVKGVEIGDGFSVITKRGSEHRDEMTLDGFNSNNSGGILGGISNGQPIIMHIAIKPTSSITVPGKTITRENEETQVVTIGRHDPCIGIRVVPIAEAMVAIVVIDHLLRQRAQCEKI
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: LGT_XANOM
Sequence: MIYLHAIDPIAFSLGPVKVHWYGLMYLAAFFSAWSLGRSRILRGRLPGVDMDGFSDLLFYGMLGVVLGGRIGYMLFYAFETFVANPLILFKVWEGGMSFHGGLLGVLVACWLWARKHRLHFFDVMDFVAPLVPLGLGFGRLGNFVGGELWGKFTQAGWGVIFPHAPELADQLPAQIQAQYAAGALNQLARHPSQLYEAALEGVVMFVVLWTFSMKPRARYALSGLFALLYGVFRFIVEFVRVPDAPIGYLAFNWLTMGQILSLPLIAVGLALLAMSRRAPVLQPVLPTPAGVEAAK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ASNA_STRE4
Sequence: MKKSFIHQQEEISFVKNTFTQYLIAKLDVVEVQGPILSRVGDGMQDNLSGVENPVSVHVLNIPNATFEVVHSLAKWKRHTLARFGFNEGEGLVVNMKALRPDEDSLDQTHSVYVDQWDWEKVIPDGQRNLAYLKETVETIYKVIRLTELAVEARYDIEAVLPKKITFIHTEELVARYPDLTPKERENAITKEFDAVFLIGIGGVLPDGKPHDGRAPDYDDWTSESENGYHGLNGDILVWNEQLGTAFELFSMGIRVDEEALKRQVDITGDQERLQFDWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKKHIGEVQTSVWPQEVRDTYDNIL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURB2_CORGL
Sequence: MDSSLAQEIAAIDGVELDSEVTFADLTTLRIGGKPRSAVRCQTTEALVSAIKLLDDASLPLLIVGGGSNLVVADGDLDVIAVIIETDDVSINLTDGLLTADAGAVWDDVVHLSVDAGLGGIECLSGIPGSAGATPVQNVGAYGTEVSDVLTRVQLLDRTTHQVSWVDASELDLSYRYSNLKFTNRAVVLAIELQLLTDGLSAPLRFGELGRRLAISEAEPHPRRPVRMVRDAVLELRRAKGMVVEHTDHDTWSAGSFFTNPIVDPALADAVFEKVGEPTMPRFPAGDGKEKLSAAWLIERAGFKKGHPGAGAKASLSTKHTLALTNRGDARASDLVALAKEIRDGVLETFGVTLVPEPVWIGISIDD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase 2, UDP-N-acetylmuramate dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SACB_ZYMMA
Sequence: MLNKAGIAEPSLWTRADAMKVHTDDPTATMPTIDYDFPVMTDKYWVWDTWPLRDINGQVVSFQGWSVIFALVADRTKYGWHNRNDGARIGYFYSRGGSNWIFGGHLLKDGANPRSWEWSGCTIMAPGTANSVEVFFTSVNDTPSESVPAQCKGYIYADDKSVWFDGFDKVTDLFQADGLYYADYAENNFWDFRDPHVFINPEDGKTYALFEGNVAMERGTVAVGEEEIGPVPPKTETPDGARYCAAAIGIAQALNEARTEWKLLPPLVTAFGVNDQTERPHVVFQNGLTYLFTISHHSTYADGLSGPDGVYGFVSENGIFGPYEPLNGSGLVLGNPSSQPYQAYSHYVMTNGLVTSFIDTIPSSDPNVYRYGGTLAPTIKLELVGHRSFVTEVKGYGYIPPQIEWLAEDESSNSAAALSLLNK
What are the official names of this protein?
Levansucrase, Beta-D-fructofuranosyl transferase, Sucrose 6-fructosyl transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 68 family.
What are the subcellular locations of this protein?
Secreted.
Protein: WSCD2_HUMAN
Sequence: MAKLWFKFQRYFRRKPVRFFTFLALYLTAGSLVFLHSGFVGQPAVSGNQANPAAAGGPAEGAELSFLGDMHLGRGFRDTGEASSIARRYGPWFKGKDGNERAKLGDYGGAWSRALKGRVVREKEEERAKYIGCYLDDTQSRALRGVSFFDYKKMTIFRCQDNCAERGYLYGGLEFGAECYCGHKIQATNVSEAECDMECKGERGSVCGGANRLSVYRLQLAQESARRYGSAVFRGCFRRPDNLSLALPVTAAMLNMSVDKCVDFCTEKEYPLAALAGTACHCGFPTTRFPLHDREDEQLCAQKCSAEEFESCGTPSYFIVYQTQVQDNRCMDRRFLPGKSKQLIALASFPGAGNTWARHLIELATGFYTGSYYFDGSLYNKGFKGERDHWRSGRTICIKTHESGQKEIEAFDAAILLIRNPYKALMAEFNRKYGGHIGFAAHAHWKGKEWPEFVRNYAPWWATHTLDWLKFGKKVLVVHFEDLKQDLFVQLGRMVSLLGVAVREDRLLCVESQKDGNFKRSGLRKLEYDPYTADMQKTISAYIKMVDAALKGRNLTGVPDDYYPR
What is the function of this protein?
Sialate:O-sulfotransferase which catalyzes 8-O-sulfation at the Sia-glycan level using 3'-phosphoadenosine 5'-phosphosulfate (PAPS) as a donor, forming 8-O-sulfated Sia (Sia8S)-glycans.
What are the official names of this protein?
Sialate:O-sulfotransferase 2, WSC domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the WSCD family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NUBP2_DICDI
Sequence: MDKIKHKILVLSGKGGVGKSTVSSQLALYLSHIGYKVGLLDVDLCGPSIPKMMGLESKDVHKSTKGWVPVYTDESQKLGVISIQFLLGDKDTPVIWRGPKKNSMIKQFIDDVNWGEIDFLIIDTPPGTSDEHISVTEELLKHNPDGAILVTTPQAVSISDVKKEISFCNAMKLPIIGIIENMSGYVCPHCSECTNIFSSEGGKLLAEQCNIKFLGKLPIDPNLSICSERGINYFTEYPNSSTLASLKSFVDNFNFKSSTTTTATN
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The nubp1-nubp2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NUBP2 homolog.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_MYCMS
Sequence: MSKDKALLRINQLKEQLNLWSKQYYVDDNPSVDDTEYDLALKELISLETLYPELITSDSPSQKVGGMVSEKFLKITHKTPMLSLGNVFSFDEFLDFNTQISKISNTLDNQYVAELKIDGLSISLVYENGSLVSAATRGNGVVGEDVTINARTIKSIPLKISKKERVEVRGEIYLSKAEFEKINQKRLLNNEDLFINPRNAAAGTLRQLDSKIVASRNLDAFLYYYISDDSNNLTQYQSILKLNELGFKTNKETMLCKNLDEIKAYIDKYTNLKNDLDYQIDGIVFKINDKNLQNSLGFTSKIPKWAIAYKFPAEIKQTKLLDIFATVGRTGKITYNAKLEPVFLMGAKISAATLNNAEYIKTKDLRINSIVKIKKAGDVIPEVIEAIKDEDFYKLEKFKPALYCPNCHSLLEKNENEVDQFCINSSCSMKILRSLQHFSSREAMNIVSLGDRSLEILFNLKIIQNISDIYKLEEYKDQILAIDNFGLKSYLNLIDSINMSKNNSLEKVLFGLGIRHIGSKTAKILARKYQNIDNLMSASYDELIQINSIGESLALSIIDWFKIEDNLKLIDELKSFNINFNYLGAKINSDSIIANKSFVITGTLTRPREEFKTLIENNAGKVIGSISKQTDYLLAGNNVGSKLEKAKKLGVKIIDEQQFFDLLKSEKG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: PELO_METVS
Sequence: MKIIQEIPEKNIIKVMPENLDDLWHLSHIVQAYNAVYSVTERRTEDKGDKLRADRGTKRRVFLGIKVEKVSFHEEVNRLRVSGKIIHAPEDIPIGSYHTLDIEPFTQISIQKNWKKWDLTRLKEAEESGKRPKVVVVILDDSEADIFTVRDFGVKELASIKSGVSKRIDSKQNEQAKYLYYNEIITTLSEFDGKILFAGPGFSKNNIQNYISEKHKDLASKIVIESTNHTGRLGLSEILKSGIIDRIYGEARLSKESQIIEKLLEEISKKRLASYGLNSVKNSINYSAVETLLITDEFLRRNRSTVEEMVNSVENSGGKFVVISTEHDSGRQLKALGGISALLRFPVE
What is the function of this protein?
May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA.  May play a role in the release non-functional ribosomes and degradation of damaged mRNAs.  Has endoribonuclease activity.
What are the official names of this protein?
Protein pelota homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTCA_SALTI
Sequence: MQEIQKNTKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMVCLSGGKDSYTMLEILRNLQQSAPINFSLVAVNLDQKQPGFPEHILPAYLEQLGVEYKIVEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFLNMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIVRFAEAKAFPIIPCNLCGSQPNLQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLCDTNLFDFKGITHGSEVIDGGDLAFDREEIPLQPAGWQPEEDDTALEALRLDVIEVK
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_BRUO2
Sequence: MAKSKFERTKPHVNIGTIGHVDHGKTSLTAAITKFFGEFKAYDQIDAAPEERARGITISTAHVEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPAIVVFLNKCDQVDDAELLELVELEVRELLSKYEFPGDEIPIIKGSALAALEDSSKELGEDAIRNLMDAVDSYIPTPERPIDQPFLMPIEDVFSISGRGTVVTGRVERGIVKVGEEVEIVGIKATTKTTVTGVEMFRKLLDQGQAGDNIGALIRGVGREDVERGQVLCKPGSVKPHTKFKAEAYILTKDEGGRHTPFFTNYRPQFYFRTTDVTGVVTLPAGTEMVMPGDNVAMDVTLIVPIAMEEKLRFAIREGGRTVGAGIVSSIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DF221_ARATH
Sequence: MKTLFFFLTIAVLVSSCTSNIMTKSILEGKTQFSIPSLSSTIDPAYEHIGHFPDDMKIIFCQQCAFHCIEKKKNIPHCENSICRCTLENIL
What are the official names of this protein?
Putative defensin-like protein 221.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: CEGT_MAGO7
Sequence: MPLLMDGLAYAGAIWSLIVFCVQAIGLYQLFRSYSRPPPPPVSPSLTSEDVPHVTVIRPVKGLEPRLYECLISTLQQSYPRDKLSVHLCISSKEDPAYPVLKKVVVEYSATHDVRLFVETEDPLLYGTTGDTRNLGPNPKIRNISHAYREAKGDIIWIIDCNIWVSKGTAGRMVDKLCGFPAGSRPYKFVHQLPLSVDVTPPQDSGVLRTGGGRLDEMFMATTHGKFYSAINTVGVAPCICGKSNMFRKSHLDRLTDPAHNPILPKETATRPRGIDYFSAYICEDHLIGDLLWRSQVPGHGNHGLVFGDLALQPMMNNSVGSYIARRVRWLRVRKWTVLLATLVEPGVESMVCCMAFAHALTTTPWCPNPADWPIPHTWTALWSIWLAAIAVWATLDYVVYHFLHSCRSIEKDADSPDFAQGNELMKRPFGAWILAWIGREILALPIWTRAVLLGTTVTWRGTKFKVRPDQSVVDIPNAGAKSNGIGSTNRKVR
What is the function of this protein?
Catalyzes the final step in the biosynthesis of the membrane lipid glucosylceramide (GluCer), the transfer of glucose to ceramide.  Glucosylceramides play important roles in growth, differentiation and pathogenicity.
What are the official names of this protein?
Ceramide glucosyltransferase, GLCT-1, Glucosylceramide synthase, GCS, UDP-glucose ceramide glucosyltransferase, UDP-glucose:N-acylsphingosine D-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: GAG_HV192
Sequence: MGARASILRGGKLDAWERIKLKPGGKKHYMMKHLVWASRELERFALDPGLLETSEGCKQIMKQLQPALQTGTKELISLHNTVATLYCVHEKIDVRDTKEALDKIKEEQNKSQQKTQQAEAADKGKVSQNYPIVQNLQGQMVHQPISARTLNAWVKVVEEKAFSPEVIPMFTALSEGATPQDLNTMLNTVGGHQAAMQMLKDTINEEAAEWDRLHPVHAGPVAPGQMREPRGSDIAGTTSTLQEQITWMTNNPPVPVGDIYKRWIILGLNKIVRMYSPVSILDIKQGPKEPFRDYVDRFFKTLRAEQATQDVKNWMTDTLLVQNANPDCKTILRALGPGASLEEMMTACQGVGGPGHKARVLAEAMSKVNNTNIMMQRSNCKGPKRTIKCFNCGKEGHLARNCRAPRKKGCWKCGKEGHQVKDCTERQANFLGKIWPSHRGRPGNLLQNRTEPTAPPEESFRFGEETTTPSRKQETIDKELPLTSLKSLFGSDPLST
What is the function of this protein?
Plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1.
What are the official names of this protein?
Gag polyprotein, Pr55Gag.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group gag polyprotein family.
What are the subcellular locations of this protein?
[Gag polyprotein]: Host cell membrane; Lipid-anchor. Host endosome, host multivesicular body. Note=These locations are probably linked to virus assembly sites. The main location is the cell membrane, but under some circumstances, late endosomal compartments can serve as productive sites for virion assembly. SUBCELLULAR LOCATION: [Matrix protein p17]: Virion membrane; Lipid-anchor. Host nucleus. Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p7]: Virion.
Protein: PRVB1_MERCP
Sequence: AFAGILADADITAALAACKAEGSFKHGEFFTKIGLKGKSAADIKKVFGIIDQDKSDFVEEDELKLFLQNFSAGARALTDAETATFLKAGDSDGDGKIGVEEFAAMVKG
What is the function of this protein?
In muscle, parvalbumin is thought to be involved in relaxation after contraction.  It binds two calcium ions (By similarity).
What are the official names of this protein?
Parvalbumin beta 1.
What is the protein family that this protein belongs to?
Belongs to the parvalbumin family.
Protein: RS2_DEHMC
Sequence: MPTTNIKELLEAGAHFGHQTSRWHPRMKKYIFTKRNGIHIIDLEKTVVMLDKACNYINQVVSDGGKVLFVGTKKQAQEILAEEAKRCGMYFINQRWTGGILTNFHSIQSRIDYLVRLEDQQARGDFSRLPKKEAQKLGEEIARLNRTMGGFKEMTRLPDVIFVVDPIKEKIAMAEAKRMGVPLVAMVDTNCNPDEVDYPVPSNDDAMRAIKLICSKMADAVIEAQNAMKVTEVETTGEAQAETAG
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: Y1314_HAEI8
Sequence: MEIIIISGRSGAGKSVALRALEDTGYYCVDNIPLDLLPQLTDILSQSQSSVAISLDIRNIPSSANSLEQTLSTLQKHHQIKIIFLEADRATLIRRYSDSRRLHPLSLKDLSLEAAIDEEYRYLEPLIQHANLILDTTHLSTHILAERLREFLRDNSEKELKIIVESFGFKYGIPLDADYVFDVRFLPNPHWDPTLRPMTGLEAPVAEFLNSHTEVNEFIYLTRHYIDTWLPMLEKNNRSYLTIAIGCTGGKHRSVYIAQQLGEYFQAKGKTVQIQHKSLERNKKI
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein NTHI1314.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: 4HYPE_PSEAE
Sequence: MQRIRIIDSHTGGEPTRLVIGGFPDLGQGDMAERRRLLGERHDAWRAACILEPRGSDVLVGALLCAPVDPEACAGVIFFNNSGYLGMCGHGTIGLVASLAHLGRIGPGVHRIETPVGEVEATLHEDGSVSVRNVPAYRYRRQVSVEVPGIGRVSGDIAWGGNWFFLVAGHGQRLAGDNLDALTAYTVAVQQALDDQDIRGEDGGAIDHIELFADDPHADSRNFVLCPGKAYDRSPCGTGTSAKLACLAADGKLLPGQPWRQASVIGSQFEGRYEWLDGQPGGPIVPTIRGRAHVSAEATLLLADDDPFAWGIRR
What is the function of this protein?
Allows intracellular utilization of 4-hydroxyproline, one of the major constituents of host collagen, by converting trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp), which can be further metabolized by intracellular 4-hydroxy-D-proline oxidases.  Strong B-cell mitogen.  Plays an important role in the regulation of intra- and extracellular amino acid pools, allowing the bacterium to profit from host precursors and enzymatic pathways.  Cannot use L-proline, trans-3-hydroxy-L-proline (t3LHyp) and pyrrolidone-5-carboxylate (P5C) as substrate.
What are the official names of this protein?
4-hydroxyproline 2-epimerase, 4Hyp 2-epimerase, 4HypE, Hydroxyproline-2-epimerase, PaHyPRE.
What is the protein family that this protein belongs to?
Belongs to the proline racemase family.
Protein: PLDB1_ARATH
Sequence: MDNHGPRYPYPYGQYPYPYPYPAPYRPPSSEPYPPPPTNQYSAPYYPYPPPPYATPPPYASPPPPHQHTSGSHSGPLDYSHNPQPSSLAAAPPEYHRHSFDYQPSPYPYQPQGNFGAYGPPPPHYSYQEPAQYPPPETKPQEPLPPPQQTQGFQEYRRQDCLSTGGTGHDNVSNSGSSYPPVDELLGGLHISTNQPGPSVPQLSSLPSNSWQSRPGDLYGYPNSSFPSNSHLPQLGRVDSSSSYYASTESPHSADMQMTLFGKGSLKVLLLHGNLDIWIYHAKNLPNMDMFHKTLGDMFGRLPGKIEGQLTSKITSDPYVSVSVAGAVIGRTYVMSNSENPVWMQHFYVPVAHHAAEVHFVVKDSDVVGSQLIGLVTIPVEQIYSGAKIEGTYPILNSNGKPCKPGANLSLSIQYTPMDKLSVYHHGVGAGPDYQGVPGTYFPLRKGGTVRLYQDAHVPEGMLPGIRLDNGMSYEHGKCWHDMFDAIRQARRLIYITGWSVWHKVKLIRDKLGPASECTLGELLRSKSQEGVRVLLLIWDDPTSRSILGYKTDGVMATHDEETRRFFKHSSVQVLLCPRNAGKRHSWVKQREVGTIYTHHQKNVIVDADAGGNRRKIIAFVGGLDLCDGRYDTPQHPLFRTLQTIHKDDFHNPTFTGNLSGCPREPWHDLHSKIDGPAAYDVLTNFEERWLKAAKPSGIKKFKTSYDDALLRIDRIPDILGVSDTPTVSENDPEAWHVQIFRSIDSNSVKGFPKDPKDATCKNLVCGKNVLIDMSIHTAYVKAIRAAQHFIYIENQYFIGSSYNWNAHKDIGANNLIPMEIALKIAEKIRANERFAAYIVIPMWPEGVPTGAATQRILYWQHKTIQMMYETIYKALVETGLEGAFSPQDYLNFFCLGNREMVDGIDNSGTGSPSNANTPQALSRKSRRFMVYVHSKGMVVDDEYVVIGSANINQRSMEGTRDTEIAMGAYQPQHTWARKHSGPRGQIYGYRMSLWAEHMATLDDCFTQPESIECVRKVRTMGERNWKQFAAEEVSDMRGHLLKYPVEVDRKGKVRPLPGSETFPDVGGNIVGSFIAIQENLTI
What is the function of this protein?
Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA).  Plays an important role in various cellular processes, including phytohormone action, vesicular trafficking, secretion, cytoskeletal arrangement, meiosis, tumor promotion, pathogenesis, membrane deterioration and senescence.  Involved in regulating stomatal movement and plant-water status (PubMed:11722757).  Can use phosphatidylserine (PS) and phosphatidylethanolamine (PE) as substrates only in the presence of PIP2.  Can use phosphatidylcholine (PC), phosphatidylglycerol (PG) or N-acylphosphatidylethanolamine (NAPE) as substrates in the presence of PE and PIP2 (PubMed:9578608).  Modulates defense responses to bacterial and fungal pathogens (PubMed:23577648).
What are the official names of this protein?
Phospholipase D beta 1, AtPLDbeta1, PLD beta 1, PLDbeta.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. C2-PLD subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: SODM_THET2
Sequence: MPYPFKLPDLGYPYEALEPHIDAKTMEIHHQKHHGAYVTNLNAALEKYPYLHGVEVEVLLRHLAALPQDIQTAVRNNGGGHLNHSLFWRLLTPGGAKEPVGELKKAIDEQFGGFQALKEKLTQAAMGRFGSGWAWLVKDPFGKLHVLSTPNQDNPVMEGFTPIVGIDVWEHAYYLKYQNRRADYLQAIWNVLNWDVAEEFFKKA
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.