PharMolix/UniProtQA huggingface dataset:
Protein: POLS_SINDV
Sequence: MNRGFFNMLGRRPFPAPTAMWRPRRRRQAAPMPARNGLASQIQQLTTAVSALVIGQATRPQPPRPRPPPRQKKQAPKQPPKPKKPKTQEKKKKQPAKPKPGKRQRMALKLEADRLFDVKNEDGDVIGHALAMEGKVMKPLHVKGTIDHPVLSKLKFTKSSAYDMEFAQLPVNMRSEAFTYTSEHPEGFYNWHHGAVQYSGGRFTIPRGVGGRGDSGRPIMDNSGRVVAIVLGGADEGTRTALSVVTWNSKGKTIKTTPEGTEEWSAAPLVTAMCLLGNVSFPCDRPPTCYTREPSRALDILEENVNHEAYDTLLNAILRCGSSGRSKRSVIDDFTLTSPYLGTCSYCHHTVPCFSPVKIEQVWDEADDNTIRIQTSAQFGYDQSGAASANKYRYMSLKQDHTVKEGTMDDIKISTSGPCRRLSYKGYFLLAKCPPGDSVTVSIVSSNSATSCTLARKIKPKFVGREKYDLPPVHGKKIPCTVYDRLKETTAGYITMHRPRPHAYTSYLEESSGKVYAKPPSGKNITYECKCGDYKTGTVSTRTEITGCTAIKQCVAYKSDQTKWVFNSPDLIRHDDHTAQGKLHLPFKLIPSTCMVPVAHAPNVIHGFKHISLQLDTDHLTLLTTRRLGANPEPTTEWIVGKTVRNFTVDRDGLEYIWGNHEPVRVYAQESAPGDPHGWPHEIVQHYYHRHPVYTILAVASATVAMMIGVTVAVLCACKARRECLTPYALAPNAVIPTSLALLCCVRSANAETFTETMSYLWSNSQPFFWVQLCIPLAAFIVLMRCCSCCLPFLVVAGAYLAKVDAYEHATTVPNVPQIPYKALVERAGYAPLNLEITVMSSEVLPSTNQEYITCKFTTVVPSPKIKCCGSLECQPAAHADYTCKVFGGVYPFMWGGAQCFCDSENSQMSEAYVELSADCASDHAQAIKVHTAAMKVGLRIVYGNTTSFLDVYVNGVTPGTSKDLKVIAGPISASFTPFDHKVVIHRGLVYNYDFPEYGAMKPGAFGDIQATSLTSKDLIASTDIRLLKPSAKNVHVPYTQASSGFEMWKNNSGRPLQETAPFGCKIAVNPLRAVDCSYGNIPISIDIPNAAFIRTSDAPLVSTVKCEVSECTYSADFGGMATLQYVSDREGQCPVHSHSSTATLQESTVHVLEKGAVTVHFSTASPQANFIVSLCGKKTTCNAECKPPADHIVSTPHKNDQEFQAAISKTSWSWLFALFGGASSLLIIGLMIFACSMMLTSTRR
What is the function of this protein?
Class II viral fusion protein.  Fusion activity is inactive as long as E1 is bound to E2 in mature virion.  After virus attachment to target cell and endocytosis, acidification of the endosome would induce dissociation of E1/E2 heterodimer and concomitant trimerization of the E1 subunits.  This E1 trimer is fusion active, and promotes release of viral nucleocapsid in cytoplasm after endosome and viral membrane fusion.  Efficient fusion requires the presence of cholesterol and sphingolipid in the target membrane.
What are the official names of this protein?
Structural polyprotein, p130.
What is the protein family that this protein belongs to?
Belongs to the alphavirus structural polyprotein family.
What are the subcellular locations of this protein?
[Capsid protein]: Virion. Host cytoplasm. Host cell membrane. Host nucleus. Note=Shuttles between the cytoplasm and the nucleus. SUBCELLULAR LOCATION: [Precursor of protein E3/E2]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Spike glycoprotein E2]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [6K protein]: Host cell membrane; Multi-pass membrane protein. Virion membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Spike glycoprotein E1]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein.
Protein: RPTN_HUMAN
Sequence: MAQLLNSILSVIDVFHKYAKGNGDCALLCKEELKQLLLAEFGDILQRPNDPETVETILNLLDQDRDGHIDFHEYLLLVFQLVQACYHKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQNHQR
What is the function of this protein?
Involved in the cornified cell envelope formation.  Multifunctional epidermal matrix protein.  Reversibly binds calcium.
What are the official names of this protein?
Repetin.
What is the protein family that this protein belongs to?
Belongs to the S100-fused protein family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RL28_PSEA8
Sequence: MSRVCQVTGKGPVTGNNISHAHNKTRRRFLPNLQHHRFWVESEKRFVRLRVSAKGMRIIDKRGIEAVLADLRARGEKF
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: ODO1_BUCBP
Sequence: MYKNEFNSSWMSSFNSSYIDNLYNKFLLDPTSIDNSWYIVFTELSKENYINSTNKYLNNKFQDSKDTIKLTIELLINIFRTLGYKFAHLNPLDTFKNDNSLSLKKFLKSSEAFRIQDSYLVKLSQYVLDDITTKNVYDDYKNIYCKRIGYQFMHIHNSNEMNWIKNYIETKHSNILKKKKKIQILKHLIISEMLEKYFSSKFPSIKRFSIEGAESLIPMLKEVIKYTKKFNLHKIIFGMSHRGRLNVLANILDKPIKTIFNEFCENNSNNFNSGDVKYHMGFCCTKTIGLRKIILDLKSNPSHLEVINPVVVGSSRAYIDSNDNLNDENILPIIIHGDAAISGQGVVQELLNMSQARGYKVGGTIHIVVNNQIGFTTSKVKDLRTSQYCTDIAKMIDSPIFHVNADDPESVIFVTHLALNYRFCFKKDVFINLVCYRRHGHNEIDDPSITQPVLYSKIKNHPTTATSYYNKLLLKNIINKSFLITYQKKIKKKLDVEYNLHNKKMSEKRLKCCSIVKADYINVSNTPINNISQSDLTILAKKIFSIPNNIEVHNRVFKIYKDRLKMANNEKLFDWGASELLAYASLLNEGISCRLSGEDVCRGTFFHRHAVIHDQKNDSKYIPLKNIKLKQGNFYIWDSVLSEEATLAFEYGYSIDQKNTLNVWEAQFGDFANGAQIIIDQFICSGEQKWNVTCNLVMLLPHGYEGQGPEHSSARIERYLQLSANNNIKIIIPTISSQIYHIIRKQAFSLIKKPLIIMSPKSLLRFPLAASSLSELSNGKFRTVIDEIDNLDTKKVQRIILCSGKIYYDLLTQRRINQQKNIVILRIEQIYPRPTKKLSAILYNYKDVHDYIWCQEEPCNQGAWLYHKSYLKKLLPKHSKLNYVGRSSSASPATGYMKIHKEQQKKIIYDALNISD
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
Oxoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: HEM1_YERP3
Sequence: MTLLALGINHKTAPVSLRERVTFSPESMDQALNSLLQQPLVQGGVVLSTCNRTELYLSVEQQENLHEQLTAWLCNYHKLSPDDVRQSLYWHHGNDAVRHLMRVASGLDSQVLGEPQILGQVKKAFAESQRGQSLSSELERLFQKSFSVAKRVRTETEIGASAVSVAFAACSLARQIFESLSELHVLLVGAGETIELVARHLREHQVKHMIIANRTRERAQSLASEVGAEVITLPEIDARLADADIIISSTASPLPIIGKGMVERALKTRRNQPMLFIDIAVPRDIEPEVGKLSNAYLYSVDDLQAIIQHNMAQRQAAAVQAESIVQQESMNFMTWLRAQGAVETIRDYRSQAEQVRSEMTAKALVAIEQGANVEQVINELAYKLTNRLIHAPTKSLQQAASDGDMERLQLLRDSLGLDQH
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: GLGE_CHLTE
Sequence: MKPEFVLPAPIRLDRPFDGRRRVVIDRVFPEIDGGRFPVKRVEGDRMTVEADIFTDGADTIVAELLYRRKGEAAWSAVPMTHIGNDRWKASFEVGAPGMCEYTVQGWVDHFETWRKGLQKKLDAGQDVSLDLRIGATIVELGAARAKDEDAGTLHHYVGLLSVGGSDAAVEAALSEGLLAAMRRSPEKAMATLYDKILLLQIDQKKAGFSTWYEFFPRSWSEEPGKHGTFRDCIKLLPRIARMGFDVIYLPPIHPIGLTKRKGKNNALVAGPDDPGSCWAIGSADGGHTSVHPELGTMEEFEAFVQEAEAQGISVALDIAFQCSPDHPWVKEHPQWFRWRPDGTVQFAENPPKRYEDILPIDFESEDWQNLWIALREVFLFWIGKGVKIFRVDNPHTKAFGFWEWALGSIREQYPETMFLAEAFTRPKLMARLAKGGYTHSYTYFTWRNTKHELQEYLTELTQTELREYMRPNFWPNTPDILHEELQGGSRARFIIRFVLAATLSSNYGIYGPAYELCEHVPYPGKEEYLDSEKYEIKQWDLDRPGNIRSEIAMVNRIRHNNPALQQTSDITFVKIEVSQGQEHDQLMGYVKCSPDGANIILTVVTLDDRNTQGGWLRFPLEKFGRPHTERFTVEDLISGRTFEWNGEWNYVELNPHQMPAHIFRVNLPS
What is the function of this protein?
Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans.  Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.
What are the official names of this protein?
Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, GMPMT, (1->4)-alpha-D-glucan:maltose-1-phosphate alpha-D-maltosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
Protein: RS19_ENDTX
Sequence: MSRSTKKGPYVDEKLFEKMQKLNKTGDRKVVKTWARASVITPEFVGHTIAIHNGKKFFPIFISEQMVGHKLGEFAPTRTFKGHGGMTKQETSLV
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: Y294_PSEMY
Sequence: MRVWIDADACPRAARDQVVKFALKRGFEVVLVAGQAVARPNFACVKLIVVPSGPDAADDHLVEHAVPGELVICSDVPLADRLVKKGVAALDPRGREFDERNMGERLAVRNLFTDLREQGQVGGGQAPYSEKDRQAFANALDRILTRLSR
What are the official names of this protein?
UPF0178 protein Pmen_0294.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: SP5G_CALBD
Sequence: MQVTDVRIRKITNEGRMKAIVSVTFDNCFVVHDIKIIEGQNGLFIAMPSRKTPEGEFKDIAHPINQETRDMVQKAVIEKYEAVISAGE
What is the function of this protein?
Could be involved in septation.
What are the official names of this protein?
Putative septation protein SpoVG.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: YMFN_ECOLI
Sequence: MSTKLTGYVWDGCAASGMKLSSVAIMARLADFSNDEGVCWPSIETIARQIGAGMSTVRTAIARLEAEGWLTRKARRQGDGSSPHCAVVDEYHEHATDALYTTMLTGMGARRQPLMWAITTAGYNIEGPCYDKRREVIEMLNGSVPNDELFGIIYTVDEGDDWTDPQVLEKANPNIGVSVYREFLLSQQQRAKNNARLANVFKTKHLNIWASARSAYFNLVSWQSCEDKSLTLEQFEGQPCILAFDLARKLDMNSMARLYTREIDGKTHYYSVAPRFWVPYDTVYSVEKNEDRRTAERFQKWVEMGVLTVTDGAEVDYRYILEEAKAANKISPVSESPIDPFGATGLSHDLADEDLNPVTIIQNYTNMSDPMKELEAAIESGRFHHDGNPIMTWCIGNVVGKTIPGNDDVVKPVKEQAENKIDGAVALIMAVGRAMLYEKEDTLSDHIESYGIRSL
What are the official names of this protein?
Protein YmfN.
What is the protein family that this protein belongs to?
Belongs to the phage terminase family.
Protein: SLT11_NEUCR
Sequence: MPPQIKHDLNRSGWEATDFPSVCENCLPENPYVKMLKEDYGAECKLCTRPFTVFSWAADRAHARKKRTNICLTCARLKNACQCCILDLQFGLPIIIRDKALELVAPGPQSEINREYFAQNNERAIEEGRAGVEEYEKADEKARELLRRLAQSKPYFRKGREVDEEGNPVNGSSSGAGRATGGNPAVGAGVGGVGPIRTRDSRAAAAAGARPGGGRRPNAAPAPPPGPKDWLPPADKSIMSLFVTGIEDDLPEFKIRDFFKAFGKIKSLVVSHMSHAAFVNYETREAAEKASAECKGRAVIAGCPLRVRWSVPKALGTMNKEQRSEMLRDGRSAFGSGQKTGGQKAIGGQNAQGGASGAQKDDASNLTIAAPPGAADVQYASLSGN
What is the function of this protein?
Involved in pre-mRNA splicing.  Facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome.  Binds to RNA (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing factor slt-11.
What is the protein family that this protein belongs to?
Belongs to the SLT11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MUTS_RHOPA
Sequence: MTIRPDIALPPDAAPPPEAPAKMSPMMEQYHEIKAANPGLLLFYRMGDFYELFFEDAEIASRALGITLTKRGKHLGADIPMCGVPVERSDDYLHRLIALGHRVAVCEQTEDPAAARARKSVVRRDVVRLITPGTLTEDTLLDARANNYLLAIARARGSAGADRIGLAWIDISTGEFCVTECSTAELAATLARINPNEAIVPDALYSDTELAPTLRELAAVTPLTRDVFDSATAERRLCDYFAVATMDGLAALSRLEATAAAACVTYVDRTQLGKRPPLSPPAREATGSTMAIDPATRANLELTRTLAGERRGSLLDAIDCTVTAAGSRLLAQRLAAPLTDAATIARRLDAVEAFAVDSGLREQIRSSLRAAPDMARALARLSLGRGGPRDLANLRDGIRAADEVLVQLAQLASPPQEIASAMAALQRPSRELCAELGRALADDLPLLKRDGGFVREGYEPALDETRKLRDASRLVVASMQARYADDTGIKALKIRHNNVLGYFVEVSAQHGEKLMAPPLNATFIHRQTLAGQVRFTTAELGEIEAKIANAGDRALGLELEIFDRLAGSIDAAGDDLRAAAHAFALLDVATALAKLASDDNYVRPEVDESLAFAIEGGRHPVVEQALKRAGEPFIANACDLSPGPAQKNGQIWLLTGPNMAGKSTFLRQNALIALLAQVGSFVPAIRARIGIVDRLFSRVGAADDLARGRSTFMVEMVETAAILNQASERALVILDEIGRGTATFDGLSIAWAAIEHLHEQNRCRSLFATHYHELTALSAKLPRLFNATVRVKEWRGEVVFLHEVLPGSADRSYGIQVAKLAGLPPSVVSRAKAVLAKLEANDRGQPKTLIDDLPLFAITARAPAEAAPPSEAEQLIDAVKALHPDEMTPREALDALYALKAKLPKAD
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: EFTS_JANSC
Sequence: MAITASMVKELRDTTGAGMMDAKKALTETDGDMDAAVDWLRTKGLAKAAKKSGRTAAEGLVAVAVSGSTGVAVEVNSETDFVGKNAEFQEMVAGIAQVALGADDTEALLAADMGGKSVADTVTAKVATIGENMGVRRMAKLEGDIVVSYVHNAAADGMGKIGVLIATKGGDAGFAKQVAMHVAAVNPASLDEASVDPEMVEKERQVQIDIARESGKPEQVIEKMIVGRMKKYLSEITLVNQAFVVNPDLTVGEAAKEASAEITGFVRLEVGEGIEKKVENFAEEVAKTAKG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPG_FRAP2
Sequence: MSEKKYTFETEVDKLLHLVIHSLYSNREIFLRELVSNSSDAIEKLRYESISNAALNEDDTDYAIRIDFDKDAKTITVSDNGIGMTEEEVIENLGTIAKSGTKKFLESLTGDKSKDNELIGQFGVGFYSSFIVADKVTVRTRKAGQDKSQATKWVSDAQNGFTVETITKEKRGTEITLHIKEDQLDLLDYHLLKSLVNKYSDCINTPIQMKKVEHDKDGKQIIKDEYETVNNTKAIWLRSKDEVTDEEYQEFYKYISHDFADALMWIHNKVEGNLEYNSLLYIPQNKPFDFWNRDKDYGLSLYVRRVFIMENKELLPPYLRFVKGVIDSADLPLNVSREILQHNKVIDKIKKAITTKILSELKKLASKDTEKYQKFWDSFGQVLKEGVSDDYSNKEKIAGLLRFATTESGDAKQTVSLADYVSRMKEGQDTIYYITSDSYKAAVNNPQLEAFKKKGIEVILMTDRIDEWMMSTLTEFDGKHMKSIIKGDIDLDKFETPENKEKFEKEAKDFEKVLKEIKEVLKDKVEDVRLSKRLTDSPSCVVVNDYGMSLHMQKMMEEAGQGFMPGMGMKPILELNAEHNLVQKLKNEADTEIFADLSELLLLQAMFVEGAKIEDPMAFVKLVNKYIR
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_GRABC
Sequence: MNTDDFGSAGEQARILAHALPFMRRYAGATVVVKYGGHAMGDERLAEQFGADIALLKQVGINPVVVHGGGPQINDMLKRLAIQSRFVDGLRVTDAAMVEVVEMVLAGTVNKMVAGLINRAGAMAVGICGKDGGLIHARKLQRTAIDPDSHIEKALDLGFVGEPAHIDVRVIHALTGAGLIPVIAPVGIGEDGQTYNINADSAAGAIAGALGAKRLLMLTDVPGVLDTDKKLIPEMSAADVKAGIADGTITGGMIPKVECCVDAVEKGVRGAVILDGRQPHACLLEMFTEGGIGTLIRG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOBA1_ECOLX
Sequence: MGLSHKERREYGRSYKRDNNRTAPFSCWPRWIRPGGWSGHGGMSGTTRTGVTARLAFWGGWLSPCLSRAGEKPSCVRTSTRTQIITCCSRLTCSGLPGARAGWLSGLCWRGSGVLLLDGHFAAADEAVNRKLNRRAGAQPATGEMTDVRQPAFRGAGTVNALARFFHGRGPETAGVFLGKDEQGEPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRSVRDFGDAVVYFDQRGPVAALLPAHCPNFTLLDLRPGKPAQLNLFRDLDQYALKNLLVAGFNLSETGHVADHYRISEQKAAKLIAEQVSAGGKHSAGAGGGVRAAGGPEKGREGADHQAGERGRPERPADGQRHRRGGDNQRRRLLYVIGSMDDEAVIRVQKMLFARCAQIIIARDEFRRWPHASIMLDEIKYLLSKYVLNALGTVRSRDCNLRLAHHAGRLRAAGQDLPADFVKTTVLDNTPIRWFYRAASQESRSGAGQTGEIRVDVERRGPAGRRGTWSISAGTASSRRSRPLFDVNTLQHLLTGSR
What is the function of this protein?
This protein is essential to promote the specific transfer of the plasmid in the presence of conjugative plasmids.
What are the official names of this protein?
Mobilization protein A, Protein B.
Protein: TYPH_BURMA
Sequence: MTFLPQEFIRKVRDRAPLDTADVARFVQGVTAGDVTEGQIAAFAMAVYFNELPLSARIALTLAQRDSGDVLDWRGARLNGPVVDKHSTGGVGDLTSLVIGPMVAACGGYVPMISGRGLGHTGGTLDKLEAIPGYDVAPSVDMLRRVVRDAGLAIVGQTAQLAPADKRIYAVRDVTATVESISLITASILSKKLAAGVGALAMDVKVGSGAFMPSAEQSAELARSIVDVGNGAGMRTAATLTDMNQALAPCAGNAIEVRCAIDFLTGAARPARLEAVSFALAAQMLTMGGLAADAHDARRRLRAVLESGAAAERFARMVAALGGPADLVERPERHLPRAAAAAPVAAARAGWIERIDARALGLAVVGLGGGRAKIGDTLDYSVGLSALAELGERVEAGQPLATVHARDADSAAQATDAVRRAYRIGAEPPAQTRVVHAVIE
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: CP1A1_CHESA
Sequence: MALMILPFIGALSVSESLVAVVTVCLVYLIIKSFQDKIPEGLSRLPGPKPLPIIGNVLEVGSRPYLSLTEMGKRYGNVFQIQIGMRPVVVLSGNETVRQALIKQGDEFAGRPDLYSFRFISEGKSLAFSTDQAGVWRARRKLAYSALRSFSTLEGTTPEYSCVLEEHISKEAKYLIQQLDTVMKADGSFDPFRYIVVSVANVICGMCFGRRYDHHDQELLSLVNLSDEFGQVVGSGNPADFIPILQYLPNKTMKKFVSINDRFISFVQKIVSEHYATFNKDNIRDITDSLIDHCEDRKLDENANVQMSDEKVVGIVNDLFGAGFDTISTALSWSVMYLVAYPEIQEXLYQELKENVGLDRTPVLSDRNNLPLLESFILEIFRHSSFLPFTIPHCTTKDTSLNGYYIPKDTCVFINQWQINHDPELWKEPSSFNPDRFLSADGTEVNKVDGEKVMIFGMGKRRCIGEVIARNEVYLFLAILIQKLHFCNLPGEPLDMTPEYGLTMKHKRCQLRATARVRSDH
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 1A1, CYPIA1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: Y4160_DICDI
Sequence: MKIYVIWSFYVLATINKQDYLPKLEFIFHKICIMFKSYYKEYEFHIKP
What are the official names of this protein?
Putative uncharacterized protein DDB_G0281365.
Protein: DRAM2_HUMAN
Sequence: MWWFQQGLSFLPSALVIWTSAAFIFSYITAVTLHHIDPALPYISDTGTVAPEKCLFGAMLNIAAVLCIATIYVRYKQVHALSPEENVIIKLNKAGLVLGILSCLGLSIVANFQKTTLFAAHVSGAVLTFGMGSLYMFVQTILSYQMQPKIHGKQVFWIRLLLVIWCGVSALSMLTCSSVLHSGNFGTDLEQKLHWNPEDKGYVLHMITTAAEWSMSFSFFGFFLTYIRDFQKISLRVEANLHGLTLYDTAPCPINNERTRLLSRDI
What is the function of this protein?
Plays a role in the initiation of autophagy.  In the retina, might be involved in the process of photoreceptor cells renewal and recycling to preserve visual function.  Induces apoptotic cell death when coexpressed with DRAM1.
What are the official names of this protein?
DNA damage-regulated autophagy modulator protein 2, Transmembrane protein 77.
What is the protein family that this protein belongs to?
Belongs to the DRAM/TMEM150 family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein. Photoreceptor inner segment. Apical cell membrane. Note=Localized to photoreceptor inner segments and to the apical surface of retinal pigment epithelial cells.
Protein: RECR_NEOSM
Sequence: MDKKIKALIKLAENLPGLGPKSARRIVLHLLKSRETTLIRFIDTMQLLYETIKHCELCGNLESESPCSICRSTKRSSDIVCVVEEITDLWAIEKAGVHNGRYHVLNGALSIVDGITPETLQIEKLKRRVSSGAVKELIIATNATVEGQTTAQYIVEVLKGTQVKLSFLAHGIPVGSEMDYLDEGTLGIAFANRRAV
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: SLP_BACSU
Sequence: MRYRAVFPMLIIVFALSGCTLSTINPMKKSRIDNIHHTQILFFSDENQIDQEAPYYDALLDLEKDYPEQIDKMKVYDKKEGWEDEIETVPTLMVVDQRHVVVKIEGCVKKKEDIIKPLQHVLSK
What are the official names of this protein?
Pal-related lipoprotein.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: NADE_FUSNN
Sequence: MNKLDLNLKEVHNELVEFLRENFKKAGFSKAVLGLSGGIDSALVAYLLRDALGKENVLAIMMPYKSSNPDSLNHAKLVVEDLKINSKTIEITDMIDAYFKNEKEATSLRMGNKMARERMSILFDYSSKENALVVGTSNKTEIYLGYSTQFGDAACALNPIGDLYKTNIWDLSRYLKIPNELIEKKPSADLWEGQTDEQEMGLTYKEADQVMYRLLEENKTVEEVLAEGFNKDLVDNIVRRMNRSEYKRRMPLIAKIKR
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: AB3B_ARATH
Sequence: MEEKTKTVPFYKLFSFSDSTDVLLMIVGSIGAIGNGVGFPLMTLLFGDLIDSIGQNQSNKDIVEIVSKVCLKFVYLGLGTLGAAFLQVACWMITGERQAARIRSLYLKTILRQDIGFFDVETSTGEVVGRMSGDTVLILEAMGEKVGKFIQLIATFVGGFVLAFVKGWLLTLVMLVSIPLLAIAGAAMPIIVTRASSREQAAYAKASTVVEQTLGSIRTVASFTGEKQAMKSYREFINLAYRASVKQGFSMGLGLGVVFFVFFCSYALAIWFGGEMILKKGYTGGEVVNVMVTVVASSMSLGQTTPCLTAFAAGKAAAYKMFETIERKPSIDAFDLNGKVLEDIRGEIELRDVCFSYPARPMEEVFGGFSLLIPSGATAALVGESGSGKSSVISLIERFYDPSSGSVLIDGVNLKEFQLKWIRGKIGLVSQEPVLFSSSIMENIGYGKENATVEEIQAAAKLANAANFIDKLPRGLETLVGEHGTQLSGGQKQRIAIARAILKDPRILLLDEATSALDAESERVVQEALDRVMMSRTTVIVAHRLSTVRNADMIAVIHRGKIVEEGSHSELLKDHEGAYAQLIRLQKIKKEPKRLESSNELRDRSINRGSSRNIRTRVHDDDSVSVLGLLGRQENTEISREQSRNVSITRIAALNKPETTILILGTLLGAVNGTIFPIFGILFAKVIEAFFKPPHDMKRDSRFWSMIFVLLGVASLIVYPMHTYLFAVAGGRLIQRIRVMCFEKVVHMEVGWFDDPENSSGTIGSRLSADAALIKTLVGDSLSLSVKNAAAAVSGLIIAFTASWKLAVIILVMIPLIGINGYLQIKFIKGFTADAKAKYEEASQVANDAVGSIRTVASFCAEEKVMEMYKKRCEDTIKSGIKQGLISGVGFGISFFVLYSVYASCFYVGARLVKAGRTNFNDVFQVFLALTMTAIGISQASSFAPDSSKAKGAAASIFGIIDGKSMIDSRDESGLVLENVKGDIELCHISFTYQTRPDVQIFRDLCFAIRAGQTVALVGESGSGKSTVISLLQRFYDPDSGHITLDRVELKKLQLKWVRQQMGLVGQEPVLFNDTIRSNIAYGKGGDEASEAEIIAAAELANAHGFISSIQQGYDTVVGERGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERVVQDALDRVMVNRTTVVVAHRLSTIKNADVIAVVKNGVIVEKGTHETLINIEGGVYASLVQLHISASS
What are the official names of this protein?
ABC transporter B family member 3, ABC transporter ABCB.3, AtABCB3, P-glycoprotein 3, Putative multidrug resistance protein 3.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: IMA8_PIG
Sequence: MPILEAPEERLRKFKYRGKDASVRRQQRLAVSLELRKAKKDEQALKRRNITTASDPFVQQTNGAKLTLQEIIHGVNASDPEQCFQATQAARKMLSQERNPPLKLMVEAGLIPRLVQLLRSSLHPCLQFEAAWALTNIASGASELTRAVVEGGAIQPLVELLASSHMSVCEQAVWALGNIAGDGAEFRDIVISSNAIPHLLALASSNVPVTFLRNIVWTLSNLCRNKNPCPCDNAVKQMLPVLSHLLQHRDSEVLSDTCWALSYLTDGCDERIGQVVDMGVLPRLVELMTSSELNVLTPSLRTVGNIVTGTDPQTQLAIDAGLLSVLPHLLLHPRSSIQKEAAWALSNVAAGPHQHIQQLIACGALPPLVALLKNGEFKVQKEAVWTVANFTTGGTVDQLVQLVQAGVLEPLINLLDIQDTKMVIIILDVIFFILQAAEKISQKENMCLLIEGLGGIDKIEALQLHENRQVALTALSIIERYFSEEEDAGTLSALLQDHECLTPLTKT
What is the function of this protein?
Functions in nuclear protein import.
What are the official names of this protein?
Importin subunit alpha-8, Karyopherin subunit alpha-7.
What is the protein family that this protein belongs to?
Belongs to the importin alpha family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BGLH_ECOUT
Sequence: MFRRNIITSAILLMAPLAFSAQSLAESLTVEQRLELLEKALRETQSELKKYKDEEKKKYTPATVNRSVSTNDQGYAANPFPTSRAAKPDAVLVKNEEKNASETGSIYSSMTLKDFSKFVKDEIGFSYNGYYRSGWGTASHGSPKSWAIGSLGRFGNEYSGWFDLQLKQRVYNENGKRVDAIVMMDGNVGQQYSTGWFGDNAGGENFMQFSDMYVTTKGFLPFAPEADFWVGKHGAPKIEIQMLDWKTQRTDAAAGVGLENWKVGPGKIDIALVREDVDDYDRSLQNKQQINTNTIDLRYKDIPLWDKVTLMVSGRYVTANESASEKDNQDNNGYYDWKDTWMFGTSLTQKFDKGGFNEFSFLVANNSIASNFGRYAGASPFTTFNGRYYGYHTGGTAVRLTSQGEAYIGDHFIVANAIVYSFGNDIYSYETGAHSDFESIRAVVRPAYIWDQYNQTGVELGYFTQQNKDANSNKFNESGYKTTLFHTFKVNTSMLTSRPEIRFYATYIKALENELDGFTFEDNKDDQFAVGAQAEIWW
What is the function of this protein?
May be a sugar porin with a broad carbohydrate specificity.
What are the official names of this protein?
Putative outer membrane porin BglH.
What is the protein family that this protein belongs to?
Belongs to the porin LamB (TC 1.B.3) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: SPAN1_BPMU
Sequence: MTFASKSLLLAAVFTAVLSGGLWHRLDSTRHDNQTLRRELQTEQQARHTAEWLLHGQEQTMQVFSAIRAANRAARLADETEHHDAKEKITTAITGDNCSTRPVPAVAADRLRELEKRTRAIGGDPARN
What is the function of this protein?
Component of the spanin complex that disrupts the host outer membrane and causes cell lysis during virus exit.  The spanin complex conducts the final step in host lysis by disrupting the outer membrane after endolysin action has degraded the host peptidoglycans.  Host outer membrane disruption is possibly due to local fusion between the inner and outer membrane performed by the spanin complex.
What are the official names of this protein?
Spanin, inner membrane subunit, i-spanin, gene product 23, gp23.
What are the subcellular locations of this protein?
Host cell inner membrane.