PharMolix/UniProtQA huggingface dataset:
Protein: TSAB_THEMA
Sequence: MNVLALDTSQRIRIGLRKGEDLFEISYTGEKKHAEILPVVVKKLLDELDLKVKDLDVVGVGIGPGGLTGLRVGIATVVGLVSPYDIPVAPLNSFEMTAKSCPADGVVLVARRARKGYHYCAVYLKDKGLNPLKEPSVVSDEELEEITKEFSPKIVLKDDLLISPAVLVEESERLFREKKTIHYYEIEPLYLQKSIAELNWEKKKRG
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro.  TsaB seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity).
What are the official names of this protein?
tRNA threonylcarbamoyladenosine biosynthesis protein TsaB, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaB.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family. TsaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBIB_SALPB
Sequence: MTILAWCIAWVLDFIIGDPQHWPHPVRWIGRLITFVQRIVRRYCPGDKALRIGGGVMWVVVVGATWGVAWGVLALAQRIHPWFGWSVEVWMIFTTLAGRSLARAAQEVERPLRENDLAESRIKLSWIVGRDTSQLQPAQINRGVVETVAENTVDGIIAPLFFLFLGGAPLAMAYKAVNTLDSMVGYKHEKYRAIGMVSARMDDVANYLPARLSWLLLGIAAGLCRLSGWRALRIGWRDRYNHSSPNCAWSEACVAGALGIQLGGPNNYFGERVDKPWIGDAQRDISVDDISRTIRLMWVASTLALALFIAARCGLSGVA
What is the function of this protein?
Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.  However, the true cosubstrate could be (R)-1-amino-2-propanol O-2-phosphate, leading to cobinamide phosphate.
What are the official names of this protein?
Cobalamin biosynthesis protein CbiB.
What is the protein family that this protein belongs to?
Belongs to the CobD/CbiB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PROB_KOSOT
Sequence: MAKITIKVGSNLLVQQDGQLDKRYIVELCREIGNLMSEGHQVVLVSSGARAAGYGYLNKSNAQEADLYMKQALCAVGQVQLMKLYESAMSFYGIKVAQILLTREDFSHRKRFLNLRNTLIGLTEMGILPIVNENDSVATEEIMFGDNDVLASMFAIGWNADYLLLMTSVDGVIDQNGKVIPFYREDTTNMAIAKNASSRWGSGGITSKIRAARAAAAAGIQTSICNGKKLENIAQFVLTGQTGTVFERVGPIKAKKAWIGFLSKPKGSIFINEGAKIAIENNRSLLPVGVVHIEGDFQAGDVVEIRLDDGTFLGKGIINFSSAEAKKIVGLKSDQLEDVLGYSCSKVLIHIDNLWKRDN
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGFZ_ECO45
Sequence: MAFTPFPPRQPTASARLPLTLMTLDDWALATITGADSEKYMQGQVTADVSQMTEDQHLLAAHCDAKGKMWSNLRLFRDGDGFAWIERRSVREPQLTELKKYAVFSKVTIAPDDERVLLGVAGFQARAALANLFSELPSREKQVVKEGATTLLWFEHPAERFLIVTDEATANMLTDKLRGEAELNNSQQWLALNIEAGFPVIDAANSGQFIPQATNLQALGGISFKKGCYTGQEMVARAKFRGANKRALWLLKGSASRLPEAGEDLELKMGENWRRTGTVLAAVKLEDGQVVVQVVMNNDMEPDSIFRVRDDANTLRIEPLPYSLEE
What is the function of this protein?
Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs.  It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.
What are the official names of this protein?
tRNA-modifying protein YgfZ.
What is the protein family that this protein belongs to?
Belongs to the tRNA-modifying YgfZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL8_MACNE
Sequence: MTSKLAVALLAAFLLSAALCEGAVLPRSAKELRCECIKTYSKPFHPKFIKELRVIESGPHCANTEIIVKLSDGRELCLDPKEPWVQRVVEKFVKRAENQNP
What is the function of this protein?
Chemotactic factor that mediates inflammatory response by attracting neutrophils, basophils, and T-cells to clear pathogens and protect the host from infection.  Also plays an important role in neutrophil activation.  Released in response to an inflammatory stimulus, exerts its effect by binding to the G-protein-coupled receptors CXCR1 and CXCR2, primarily found in neutrophils, monocytes and endothelial cells.  G-protein heterotrimer (alpha, beta, gamma subunits) constitutively binds to CXCR1/CXCR2 receptor and activation by IL8 leads to beta and gamma subunits release from Galpha (GNAI2 in neutrophils) and activation of several downstream signaling pathways including PI3K and MAPK pathways.
What are the official names of this protein?
Interleukin-8, IL-8, C-X-C motif chemokine 8, Chemokine (C-X-C motif) ligand 8.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: LGT_BORBU
Sequence: MPNYINYPSWLHPEVIQGIPITWYSLSYILIILISYKFIWYQIQSDNVDIKKEDYEIFMFSLVLGAILGGRLASTLVYDKSGIYYSNPWLILLPFDQHWNFTGFRGMAIHGGFLGAIIAPLITINTNLKNTNVQKYFLKLTDYGSIAFSSGYILGRLANFANAELYGRVMKGGIIFPNAEPFDTNIPGVKEFASSVGLEISPHDLLINLPRIPSQLIEGFFEGPVTFLLLWFLFKKIKKYDGFIFGVYVMLYAFFRFFIEYLREPDKELGFIITYKPITSLSEFSFLNISMGQILSLTLMLSGLIWIIVTKKIADKKIKNNTNLAYKN
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TTC32_MOUSE
Sequence: MALRPGREGGESSAALATAQARFSRGEFAEARELYSAFIGQCARHGSKCSPEDLATAYNNRGQTKYFSVDFYEAMDDYTSAIEILPSFEVPYYNRGLIRYRLGYFDEALEDFKKALDLNPGFQDAVLSLKQTILDKEEKQRRNAEKSY
What are the official names of this protein?
Tetratricopeptide repeat protein 32, TPR repeat protein 32.
Protein: MTRA_SHEB8
Sequence: MKNSLKMKNLLPALVITMAMSAVMSLCIAPNAYASKWDAKMTPEQVEATLDKKFAEGNYSPKGADSCLMCHKKSEKVMDLFKGVHGAIDSSKSPMAGLQCEACHGPLGQHNKGGNEPMITFGKQSTLSAEKQNSVCMSCHQDDKRVSWNGSHHDNADVACASCHQVHVAKDPVLSKNTEMEVCTSCHTKQKADMNKRSSHPLKWAQMTCSDCHNPHGSMTDSDLNKPSINETCYSCHAEKRGPKLWEHAPVTENCVTCHNPHGSVNDAMLKTRAPQLCQQCHASDGHASNAYLGNTGLGSNVGDNAFTGGRSCLNCHSQVHGSNHPSGKLLQR
What are the official names of this protein?
Multiheme cytochrome MtrA.
Protein: DGTP_CITK8
Sequence: MAQIDFRNKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEQYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPADAESQPLSDDRCAVAALRLREGEESLNDIRRKVRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPATHRYLMKKPGYYLSEAPYIERLRKELALAPYSRFPLTWIMEAADDISYCVADLEDAVEKRIFSVEQLYHHLYEAWGHHEKGSLFTQVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPQIFDGSFNHALLEDASSFSQLLELYKNVAIKHVFSHPDVEQLELQGYRVISGLLEIYQPLLRMSLVDFRELVEKERVKRFPIESRLFQKLSTRHRLAYVEAVSKLSPEAPEYPTLEYYYRCRLIQDYISGMTDLYAWDEYRRLMAVE
What is the function of this protein?
dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase, dGTP triphosphohydrolase, dGTPase.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 1 subfamily.
Protein: YXIM_BACSU
Sequence: MKKWMAAVFVMMLMLCFGGIENVKAAEPKVYQFDFGSGSMEPGYIGVRASDRYDRSKGYGFQTPENMRDVAASGAGVKSDAVQFLAYGTKSNNTFNVDLPNGLYEVKVTLGNTARASVAAEGVFQVINMTGDGAEDTFQIPVTDGQLNLLVTEGKAGTAFTLSALKIKKLSDQPVTNRTIYVGGDSTVCNYYPLNSSKQAGWGQMLPHYIDKHTFQVRNMASGGQIARGFRNDGQLEAILKYIKPGDYFMLQLGINDTNPKHKESEAEFKEVMRDMIRQVKAKGADVILSTPQGRATDFTSEGIHSSVNRWYRASILALAEEEKTYLIDLNVLSSAYFTSIGPERTLGLYMDGDTLHPNRAGADALARLAVQELKRQGIAGF
What are the official names of this protein?
Uncharacterized esterase YxiM.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
Protein: KAE1_SCHPO
Sequence: MGKPLIALGLEGSANKLGVGIILHDTNGSAKILANVRHTYITPPGQGFLPSDTAKHHRAWIIPLIKQAFAEAKISFKDIDCICFTKGPGIGAPLNSVALCARMLSLIHKKPLVAVNHCIGHIEMGREITGAQNPVVLYVSGGNTQVIAYSEKKYRIFGETLDIAIGNCLDRFARIIGLSNAPSPGYNIMQEAKKGKRFIELPYTVKGMDCSFSGLLSGVEAAATELLDPKNPSSVTKQDLCYSLQETGFAMLVEITERAMAHIRADSVLIVGGVGCNERLQQMMAEMSSDRGADVFSTDERFCIDNGIMIAQAGLLAYKTGDRCAVAESTITQRYRTDDVYISWRD
What is the function of this protein?
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  Pgp2 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.  The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation.  The complex is required for efficient recruitment of transcriptional coactivators.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, Pombe glycoprotease 2, t(6)A37 threonylcarbamoyladenosine biosynthesis protein kae1, tRNA threonylcarbamoyladenosine biosynthesis protein kae1.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TFB1_NEUCR
Sequence: MAPIEIPRGQASYKKREGIITLTPDKTALIWSPLPGTGPPVISLSVSNITNLQQTPKTNPKVVLRVVEKPKAPGADPAAYPFQFTHATEARNEADAIKDLLSQIIAELRGDDPSLPKPAKSGPNGAGASAAMAMASAVNSKHLPFRWFEDDMLKADVELQQSLMKKDKALAHIYNDAKLSKPDSLSDASFNSQFWATRISLLRAYAIELNQKKGSYNVLSTIKPRTENGELKLNINHEQVQLIFQQHPLVKRIYNENVPKLTESEFWSRFFLSRLSKKLRGERITDNDNTDPLFDKYLEADNTMAVPAKITATSVPPIINIEGNEENQGGFRGGNLKDVEMRPRANIPIIKTLNSLSEKIMANVAPTDVDPSAASYSKDGIADALSKQLALQDLRGDAEAQLIRLSVKDTSTFFTGNQPSLTDQEAADARLYATQVPSDVLFEVQADMDTLDSDGRGGIDLHRSIGVDPDSDDEGNNSLDSKSGPKPQHVGSRAALRFAQNQILESMKSARSHLTTTTTHGGSHTTTTNASEERPMSLPTDIAHRATLTCATTAEFLKQFWTVFNNSSNSSPEKQQELAYLADSLVRSKQRIEALADEAEKRRQEIMEKRKREIREYYQKTGRKAKWVPVGGGRDAVWAAFEGVVGGLERAVAVWEMVKSGRI
What is the function of this protein?
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II.  In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment.  In transcription, TFIIH has an essential role in transcription initiation.  When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.  Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
What are the official names of this protein?
General transcription and DNA repair factor IIH subunit tcf-29, TFIIH subunit tcf-29, RNA polymerase II transcription factor B 73 kDa subunit, RNA polymerase II transcription factor B p73 subunit, RNA polymerase II transcription factor B subunit 1, Transcription factor-29.
What is the protein family that this protein belongs to?
Belongs to the TFB1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUVA_BACC4
Sequence: MFEYVTGYVEYVGPEYVVIDHNGIGYQIFTPNPYVFQRSKQEIRVYTYHYVREDIMALYGFKTREERLLFTKLLGVSGIGPKGALAILASGQTGQVVQAIEHEDEKFLVKFPGVGKKTARQMILDLKGKLADVVPDAFVDLFSDTERFDEKKGSSAELDEALEALRALGYAEREVSRVVPELLKESLTTDQYIKKALSLLLNGKR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: MENG_STAA2
Sequence: MADNKANKEQVHRVFQNISKKYDRLNNIISFEQHKVWRKRVMKDMGVRKGTKALDVCCGTGDWTIALSKAVGPTGEVTGIDFSENMLEVGKEKTASMENVKLVHGDAMELPFEDNSFDYVTIGFGLRNVPDYLVALKEMNRVLKPGGMVVCLETSQPTLPVFKQMYALYFKFVMPIFGKLFAKSKEEYEWLQQSTFNFPGKEELKRMFEEAGFINVRVRSFTGGVAAMHLGYKEKDNTKGD
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: PHS_CHLTE
Sequence: MTQLENKHCVPCEGTAAPMASEELQRQLSSLPEWTLVDDSGTSKLVRVFTFKDFQSALDFTNRVGQLAEAEGHHPALLTEWGKVTVSWWTHAIGGIHLNDVIMATKTEKLV
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: COX1_FELCA
Sequence: MFMNRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMLWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLDNTWAKIHFTIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTTWNTISSMGSFISLTAVMLMVFMVWEAFASKREVAMVELTTTNLEWLHGCPPPYHTFEEPTYVLLK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PRTGA_DANRE
Sequence: MASFKRDLYLFLAVFLSISGVWSFSELFFIKEPHDVTAMRRDAVVLDCQAHGEAPIGIRWLKNGVTITESERVYSLSNGSLLISEVESRKDKSDEGFYQCLAQNKYGSILSQRARLTIASLSTFTQQPASIIVMEGSVARFTCKITATPPPIITWEFNRVTLPLATERITVLPSGVLQIQGVEQRDAGSYRCVAANIVSRRRSTEATLTVTPAMSPRAPQRPRIIAGPQNLTVPAHSTALLECMASGNPRPLISWSRADHKSIDVHKTKVLGNGNLIISDVNPQHAGIYFCRATTPGTRNYTIAAANITVLAPPSLVEWPESVTRPRAGTARFVCTAEGFPTPQITWLKNGEPVRSNGRIKMYNSKLVINQIIPEDDGIYQCEAENIQGSVLAMARLIVVMSDNRPSAPRNIRADTVSSSAIVLAWDRPAYNSEKVIAYSVHYMKAEGLNNEEYQIVIGNDTTRYIIDDLEAGRNYTFYIVAYMPMGASRMSDHVIQHTLEDVPLRAPELSLTSRSPSDIQVSWQPLSHKLSRGRVSAYRLSYRTSSDGTLTQLELSAHKTHQLLEGLQPDTTYLLRIAAATAVGWGEPSAWSSHRTPKASSTKVPLAPELQLESLNCTTVTLRWHLPAGSSSGLQGFKLSYHEEGQSEAAQAQIPPHHRQHTIGGLDPRKKYHIKLLAFSFMGDGYQADQTISTPGCVSVRDRLVPPPPPPHHVYAHSNSSSSVFLHWARPAFTSAQTLNYTVRCNPVGLQNASLVLYLQTAAQSLLVTDLEPNTNYEFAVRLHVDLLSSPWSPVVYQTTLPEAPSRAPVGVKVTLIEGDSALVSWKAPDDRSAAAVTHYTVLYATRRAWAAGDWQMLQREGSITMALLENLQPGQVYLVQVSASNQMGDGPFSAAVELTIHTDGHAHRTHGFSHATVFSDGFYHLDQRSMAGIAVGVCIALTCIIICILILACRSKTRKSCTTKSIRQAGGQTPPTAVRLANESAAESVEVMMPMMRDHFIDAKGGTNLIINSYGPVKPNIEKKRRKRWSFFKKNEKEVKKVSSPAYSYHPGTTLLCYTETSPENPPTTLQGLFGPSGGDSEGSHSSEGSHETSDSGRYSHDDTEATNVSIRSRPASLQDDGNQTPVHEKQLETTLQEQEMTDLHPV
What is the function of this protein?
May play a role in anteroposterior axis elongation.
What are the official names of this protein?
Protogenin A.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. DCC family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CYB_AKOLP
Sequence: MKILRKNHPLLKIINHSFIDLPTPSNISSWWNFGSLLGMCLVIQILTGLFLAMHYTSDTTTAFSSVAHICRDVNYGWLIRYLHANGASMFFICLFIHVGRGIYYGSYVLSETWNIGIILFLTTMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGSTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAAFALVHLLFLHETGSNNPSGLNSDSDKIPFHPYYTTKDLLGIFLLLLVLMILALFFPDILGDPDNFTPANPLNTPAHXXPXXXXLFAYAILRSIPNKLGGVLALILSILILAAFPLLNTSKQHGLIFRPVTQVIYWXXIANLLVLTWIGGQPVEYPFTMIGQIASITYFAIXIILIPVSNTIENNIIKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: KDSA_DECAR
Sequence: MKLCGFEAGLDQPFFLIAGPCTAESEQLCLDVAGHMKEVCARLGINYIFKASYDKANRSSGKSVRGLGLEEGLRIFSEVQRQIGVPVLTDVHTIEDIPAVAAVVDVLQTPAFLCRQTDFIHAVATCGKPVNIKKGQFLAPGDMKNVVDKAREVNNGADNIMVCERGASFGYNNLVSDMRSLAIMRETGCPVVFDATHSVQLPGGQGTTSGGQREFVPVLARAAIAVGISGLFMETHPCPEKAWSDGPNSWPLDRMESLLATLVALDKAVKTAGFEELK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y008_HIS1I
Sequence: MSPEITRETFENGPGEQTSLFHVDDCVKNHARLRKEYNLTKCPNCQRNIEKTPETADKSEQKALTDF
What are the official names of this protein?
Uncharacterized protein ORF8.
Protein: ENO_ANAPZ
Sequence: MLYSRSVAKINGVSARQILDSRGRPTVEAVVSLSDGALGVVSVPSGASVGKNEALELRDKDMNKYGGHGVTKAVENVNSIIAPRLVNTDPFNQKALDDLLIELDGTDNKSRLGANATLAVSVATAKAAAASLKLPLYRYIGGVASREMPVPLVNVINGGLHADNGLDFQEFMIMPIGASTFSDALRMCAEVFLSLKEILKSNKLSTNTGDEGGFAPNLESNDRVFCILLEAIEKAGYKPSIDFALALDVAASTFYDGKIYKFSGSSMSSAEMVSYYEELVKKYPIISIEDGIAEDDLAGWKELTVRLGKKVQLVGDDLFVTNPRLIKDFSERGLANAVLIKPNQIGTLSETIEAIRLASMSNFNSIVSHRSGDTEDPFIAHIAVALNCGQIKTGSMSRSERMAKYNELLRIEEDLCGTAILRSVKIGRH
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: CD123_XENLA
Sequence: MKKEQVLNCQFGQWYPTFKKFSIRSVIIPLPENVKDYLLDDGTLVVSGREESPGCSQRDLNCTEEDEVQWSDDESTATLTAPEFPEFSIKVQEAINSLGGSVFPKLNWSSPRDAYWIALNSSLKCTTLSDIFLLFKSSDFVTHDFTQPFIYCADDSPDPNIKYELVLRKWCELIPGAEFRCFVRENKLIGISQRDYTQYYDHISKQKEEIRKSIQYFFQEHIQYNFPDEDFVFDIYKDSQGKIWLIDFNPFGEVTDSLLFTWEELRRNLCDVPGDVENEDQDCPTFRYTNREVTVQPSPYLSYRLPKDFVDLSTGEDAHKLIDFLKLNRNRQDEDSDD
What is the function of this protein?
Required for S phase entry of the cell cycle.
What are the official names of this protein?
Cell division cycle protein 123 homolog.
What is the protein family that this protein belongs to?
Belongs to the CDC123 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDHF4_YEAST
Sequence: MLCAIKSTGYRYPRTGALNLLRGRPFNMATRKITTERIPGPPKLPREEQEEFERLQRIATSQEAIDQYNAQATGDRTKESLNSPLLTKNDIGSFSPEFSKTIPEFEGDVNPKTGEVGGPKQDPLRHGDYSFNGRVTDF
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Binds to the flavoprotein subunit SDH1 in its FAD-bound form, blocking the generation of excess reactive oxigen species (ROS) and facilitating its assembly with the iron-sulfur protein subunit SDH2 into the SDH catalytic dimer.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 4, mitochondrial, SDH assembly factor 4, SDHAF4, Found in mitochondrial proteome protein 21.
What is the protein family that this protein belongs to?
Belongs to the SDHAF4 family.
Protein: RK14_CUSRE
Sequence: MIQPQTHLNVADNSGARELMCIQIIGASNRRYAHIGDIIVAVIKEAVPNMPLERSEVVRAVIVRTRKELKRDNGMIIRYDDNAAVVIDQEGNPKGTRIFGAIPRELRQFNFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, plastid.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid.
Protein: DTD_SACD2
Sequence: MKVLIQRVSHASVVVEGQTIGAIDKGLLLFVGIEKTDSTETLERMANKVLAYRVFSDDEGKMNLNVQQIGGGVLSISQFTLAADTQKGLRPSFSCAAPPAEAQALYDKFVNLLKAKHSPIATGEFAADMKVSLLNDGPVTFMLTM
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.