PharMolix/UniProtQA huggingface dataset:
Protein: MSCL_STAS1
Sequence: MLKEFKEFALKGNVLDLAVAVVMGAAFNKIVTALVSYIIMPLIGLIFGTVDFAESWSFMGIKYGMFVQSIIDFIIIAFALFIFVKIANTLMKKEEEEEIEENTVLLTEIRDLLREKN
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYP_ECO55
Sequence: MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGERPFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGEDDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEKTVKTLLVKAVEGSSFPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVNAGPGSLGPVNMPIPVVIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPEIADIRNVVAGDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLLDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVEYLVKQIKG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_SALPA
Sequence: MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKGLFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEGGCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGARAILTEVYNGETPA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: RL30_AZOC5
Sequence: MAKASETKTVTVEQIGSPIRRPGDQRATLVGLGLNKRHRRSTLQDTPAVRGMIAKVQHLVRVVADE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: PO3F2_HUMAN
Sequence: MATAASNHYSLLTSSASIVHAEPPGGMQQGAGGYREAQSLVQGDYGALQSNGHPLSHAHQWITALSHGGGGGGGGGGGGGGGGGGGGGDGSPWSTSPLGQPDIKPSVVVQQGGRGDELHGPGALQQQHQQQQQQQQQQQQQQQQQQQQQRPPHLVHHAANHHPGPGAWRSAAAAAHLPPSMGASNGGLLYSQPSFTVNGMLGAGGQPAGLHHHGLRDAHDEPHHADHHPHPHSHPHQQPPPPPPPQGPPGHPGAHHDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSSGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGGTLPGAEDVYGGSRDTPPHHGVQTPVQ
What is the function of this protein?
Transcription factor that plays a key role in neuronal differentiation (By similarity).  Binds preferentially to the recognition sequence which consists of two distinct half-sites, ('GCAT') and ('TAAT'), separated by a non-conserved spacer region of 0, 2, or 3 nucleotides (By similarity).  Acts as a transcriptional activator when binding cooperatively with SOX4, SOX11, or SOX12 to gene promoters (By similarity).  The combination of three transcription factors, ASCL1, POU3F2/BRN2 and MYT1L, is sufficient to reprogram fibroblasts and other somatic cells into induced neuronal (iN) cells in vitro (By similarity).  Acts downstream of ASCL1, accessing chromatin that has been opened by ASCL1, and promotes transcription of neuronal genes (By similarity).
What are the official names of this protein?
POU domain, class 3, transcription factor 2, Brain-specific homeobox/POU domain protein 2, Brain-2, Brn-2, Nervous system-specific octamer-binding transcription factor N-Oct-3, Octamer-binding protein 7, Oct-7, Octamer-binding transcription factor 7, OTF-7.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFP_ACIF2
Sequence: MKISAFDIRPGNILEYEKGLWRVLKTDFVKPGKGGAFVQVEMKNIETGTKSNTRFRSGEAMEKAVVEPRTMQYLYADATGYVFMDNENFEQLILSEDLLEGQTGYLLPNTEIQVNLHNERPIGVELPPVVILEVREAEPSIKGQTATGSYKSAQMETGITVMVPQFVNAGEKIRVNTVDGSYIDRA
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-33 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y650_METJA
Sequence: MVNFMKRILIFFILFLLFCGSLKAHLIFYDKDVSQLKSLGFIGDYNGKYWLISDKCKLIKYNEIPILIVPSKPLNNIEIIKWDKYRESWLIITNNESISNVSSDIYLLEGKKLIHFGRFNFLIEDIDDNGDYFLVSAFCPDKKSKIFIIYNNKSIEDINKYLNIKIDDFSFPKIKYIPNGNFWLIVTTTLEGQNCLIKFNGTYGEDISPKLNIPKPPNKMGCYNIIEDVDFNGTSYLIVGKFSKYKDRCNYILSYENNRSKIYKYNFDGHFKRVSWINNSWIVEIVNFSRDNSYSYEYYALKNGKLKRIKVGESANFTPIVWYLGTYITDIAKINDNQYLITLKSIEDFPKYPNIGALIKLTINNSKIDKKIIYKGKGLTSIGYNGKYCLIGGKGVLLLYNGKNITDLTKRANISNSDLISSIAYGKDCWLIGLDEVNLHYPSKSLIKFDGKKFYDLTNISNITICKILKSNKEYILIGTKNVLIKYNGSFITIINYTNYEKYGLCYIFEAMDYNPKERYWLVGGVCLYNHPYSSDAILYKVYDNGSYESLPINDNLHKIYGDFGFALVSLIKYIPKNNSFLIKVWVGLNDHWLIYKNNTLTEFVTQKNPGSIEIDNYTLYIFNYYNTIEIYDNNKLLSTVELIDIPKETVCVEEYHYKEKSSYNNYLYILIFIILTIIAIYIVVKINKKLT
What are the official names of this protein?
Uncharacterized protein MJ0650.
Protein: ZG20_XENLA
Sequence: MFCKEEEPYEFPENTFGTNELLPNYQQNCTDGEAISDTKSDLAYLEVEITDAHEESNTDKPFTCTECGKTFTRKPNYESHIRAHKGEKPFSCMVCDKAFAWKSNLLVHYSVHSGEKPFSCTECDKTFSNKAQLEKHLRVHTGEKPYSCEQCGKSFAHKCVLDSHQRTHTGDKPFSCTECGKKFSQRGNLHKHLKTHKLDQPHLCAECGKTFSFKSTLLEHQKIHSEIRPLSEFGKTFSDAHNLLKHQSTFTEEQKPFPCTECGEIFSNEHELLTHQSTHTEEQKPFPCTKCWGIFSNEHELRTHQSTHTEGQKSLPSTESGGTFSNEHELLTHQSTHTEEQKHLPCTECGGTFTNEQELLAHQSTHTEEQKPLPCTECGEIFSDEHELLTHQSTHTSPSTEFGVQTTEDNHQSPSKDHTGEKPFSCSECGKSFFYKSVLKDHLVVHTGKKPYHCIECGRSYTHQSSLKSHQRTHTGVKAFSCNLCDKLSIISKLRLHYRVHSGEKPYPCTECDKTFTKKEQLESHYKVHTGEKPYPCQQCGKSFSHKSVLKLHLRTHTGDKPFSCTECGKTFTRKPNYESHLTTHTGKKPFSCTECGKEFAWKRNLEAHYKMHTGEKPFTCTECGKTFTWKSNLRSHYTTVHGISPIQYACTEEDVNVIKTEEGDSFSYMVTLEN
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Gastrula zinc finger protein xFG20-1, XlCGF20.1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL9_LEGPA
Sequence: MEVILLEKVRNLGNLGDKVHVKSGYGRNYLIPQNKAVFATEQNIELFQKRRAELEKKAQQALANAEQRAAKLNDTTIVISAMASDEGKLYGSVGVNEIKDALIEKQIEISKREIVMPEGPLHSIGNYVVEVHVHSDVVANLQVEIISAK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: SECA1_GEOTN
Sequence: MLGVLKKVFDPNKRQLARLEKIADQVDALGPEMARLSDEQLRQKTEEFKARYQQGESLDDLLVEAFAVVREGAKRVLGLYPYKVQIMGGVVLHEGDIAEMKTGEGKTLTATMPVYLNALTGRGVHVVTVNEYLASRDAKEMGQLYEFLGLTVGLNLSGMSREEKQAAYNADITYGTNNEFGFDYLRDNMVLYKEHIVQRPLYFAVVDEVDSILIDEARTPLIISGTAQKSTKLYVQANAFVRTLRKDVDYTYDEKSKSVQLTEEGMNKAERAFGIDNLFDLKHVTLNHHIQLALRAHVTMQRDVDYVVQDGKVIIVDPFTGRLMHGRRYSDGLHQAIEAKEGLEIQNESMTLATITFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMRVVVIPTNRPVIREDRPDLIYRTMEGKFRAVVEDIAQRHAKGQPVLVGTVAIETSELLSEMLKKRGIPHNVLNAKNHAKEAEIIAQAGQKGAVTIATNMAGRGTDIKLGEGVKELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGVSQFYLSLEDELMRRFGSESLMAMMDRLGMDDSQPIQSKMVTRAVESAQKRVEGNNFDARKQLLQYDDVLREQREVIYRQRFEVLDADNLRGIIEKMIRSVIERVVNTYTPKEDLPEEWNLKGVVDYLNAYLLPEGDVTEGDLRGKEPEEMIELIWAKVKARYDEKETQIPPEQMREFERVVVLRAVDMKWMNHIDAMEQLRQGIHLRAYGQVDPLREYQMEGYAMFENMIAAIEEEVATYIMKAEIHHNLERQEVAKGEAVHPKEDGEEPKKKPIRKAVRVGRNDPCPCGSGKKYKHCCGRAV
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: HPPK_MYCBO
Sequence: MTRVVLSVGSNLGDRLARLRSVADGLGDALIAASPIYEADPWGGVEQGQFLNAVLIADDPTCEPREWLRRAQEFERAAGRVRGQRWGPRNLDVDLIACYQTSATEALVEVTARENHLTLPHPLAHLRAFVLIPWIAVDPTAQLTVAGCPRPVTRLLAELEPADRDSVRLFRPSFDLNSRHPVSRAPES
What is the function of this protein?
Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.
What are the official names of this protein?
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, PPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK.
What is the protein family that this protein belongs to?
Belongs to the HPPK family.
Protein: ARGR_STAAN
Sequence: MPKKSVRHIKIREIISNEQIETQDELVKRLNDYDLNVTQATVSRDIKELQLIKVPIPSGQYVYSLPNDRKFHPLEKLGRYLMDSFVNIDGTDNLLVLKTLPGNAQSIGAILDQINWEEVLGTICGDDTCLIICRSKEASDEIKSRIFNLL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_NOSP7
Sequence: MPLPKISEARELSDEKLSDEIVAIKRQLFQLRLQKATRQLEKPHQFRQARHRLAQLLTLETERKRAASQSAKEEK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RSMH_CHLTB
Sequence: MTDSIPHIPVLVKESLSLFRGRNPVVFCDVTVGAGGHAEAFLTEFPSIERYDGSDRDLSALALSENRLLPFKDRVRLRHASFEEVDTLTSDGTYDGVLADLGVSSMQLNNLERGFSFQGEDHPLDMRMDTSRGMTASEVLNSLREEEIGEIFRNYGEEPLWRSAAAAVVHFRKKKKILTVKDLKDATSGVFPSYRLRKKIHPLTLIFQALRIYVNQEGAQLKVLLDSAFRWLRPGGRLAVISFCSLDDRPVKWAFREAEARGLGKILTKKVIMPSYEETRMNPRSRSAKLRCFEKSFEDK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_LEVBA
Sequence: MRVLLQRVSQASVSIDDTVHGQIGSGFLLLVGAQDQDTSEQIDYLVHKISHLRVFEDDAGKMNLSINDVGGQILSVSQFTLYANTKKGNRPSFVGAGDPQHASQIYDEFNQKLAATGLTVATGVFGADMQVALVNDGPVTIWFDTDA
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BEND3_MOUSE
Sequence: MNSTEISEDVEEVLKNNPVKAEGSDATLDCSRNSRASEKHLLESVLTALHDSSKRKQLDSDGQPDSVPSVKRRRLIPEALLAGMRTRENSSPCQGNGEPASRGRSGSCAWPAEEEPSTEATVPSYKKPLYGISHKIMEKKNPPSGDLLSPYELFEKANSSSGPSPLRLLSESQKRECGVGVATDGDLNIYFLIQKMFYMLNGLTTNMSQLHSKMDLLSLEVSRVKKQVSPSELVAKFQPPPEYQLTASELKQIAEQSLSCGDLACRLLLQLFPELFSDVDFSRGCSACGFAAKRKLESLHLQLIRNYVEVYYPNVKDTAVWQAECLPQLNDFFSRFWAQREMEDSQPGGQVTNFFEADQVDAGHFLDNKDQEEALSLDRSSTIASDHVVDTQDLTEFLDEASSPGEFAVFLLHRLFPELFDHRKLGEQYSCYGDGGKQELDPQRLQIIRNYTEIYFPDMQEEEAWLQQCAQRINDELEGLGLEGGSEGEAPRDDCYDSSSLPDDISVVKVEDNFEGERPGRRSKKIWLVPIDFDKLEIPQPDFEMPGSDCLLSKEQLRSIYESSLSIGNFASRLLVHLFPELFTHENLRKQYNCSGSLGKKQLDPARIRLIRHYVQLLYPRAKNDRVWTLEFVGKLDERCRRRDTEQRRSYQQQRKVHVPGPECRDLASYAINPERFREEFEGPPLPPERSSKDFCKIPLDELVVPSPDFPVPSPYLLSDKEVREIVQQSLSVGNFAARLLVRLFPELFTTENLRLQYNHSGACNKKQLDPTRLRLIRHYVEAVYPVEKMEEVWHYECIPSIDERCRRPNRKKCDILKKAKKVEK
What is the function of this protein?
Transcriptional repressor which associates with the NoRC (nucleolar remodeling complex) complex and plays a key role in repressing rDNA transcription.  The sumoylated form modulates the stability of the NoRC complex component BAZ2A/TIP5 by controlling its USP21-mediated deubiquitination (By similarity).  Binds to unmethylated major satellite DNA and is involved in the recruitment of the Polycomb repressive complex 2 (PRC2) to major satellites (PubMed:25457167).  Stimulates the ERCC6L translocase and ATPase activities (By similarity).
What are the official names of this protein?
BEN domain-containing protein 3.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=In the nucleus, observed in heterochromatic foci containing CBX1, CBX3, CBX5 and histone H3 trimethylated at 'Lys-9'. Released from chromatin during decondensation. Association with heterochromatin does not depend on sumoylation.
Protein: ASZ1_PONAB
Sequence: MAAGALRGLPVAGGGESSESEDDGWEIGYLDRTSQKLKGLLPIEEKKEKFKKAMTIGDVSLVQELLDSGISVDSTFQYGWTPLMYAASVANAELVRVLLDRGANASFEKDKQSILITACSARGSEEQILKCVELLLSRNADPNVACRRLMTPIMYAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNIVLKLLELGANKMLQTKDGKMPSEIAKRNKHHEIFNLLSFTLNPLEGKLQQLTKEDTICKILTTDSDREKDHIFSSYTAFGDLEVFLHGLGLEHMTDLLKERDITLRHLLTMREDEFTKNGITSKDQQKILAALKELQVEEIQFGELSEETKLEISGDEFLNFLLKLNKQCGHLITAVQNIITELPVNSQKITLEWASPRNFTSVCEELVNNVEDLSEEVCKLKDLIQKLQNERENDPTHIQLREEVSTWNSRILKRTAITVCGFGFLLFICKLTFQRK
What is the function of this protein?
Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons.  Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process.  Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons.  May act by mediating protein-protein interactions during germ cell maturation (By similarity).
What are the official names of this protein?
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1, Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Specifically localizes to pi-bodies, a subset of the nuage which contains primary piRNAs (By similarity).
Protein: CCX4_ARATH
Sequence: MRAVNFMYSSNNPKFRGIFNGLCAIILFIFFFDQSDIYRNPLLKNLSFVDSSGKFNRGFSQFTVPRRHLSEVDTNGSSGNSSLSGDSTVSCSGLHEHRGYADQCEFLKSNPICSPDGFFDYLKFFYCSCRDFKILGYILLGVWLVALFYLLGNTAADYFCCSLEKLSKLLRLPPTVAGVTLLPLGNGAPDVFASIAAFVGSDKGEVGLNSVLGGAVFVTCVVVGIVSLCVADKEVKIDKKCFIRDLSFFLFTLVALMVILMVGKVTVGIAIAFVSIYVFYASLVAANEILRKHSRRLKLDSITPLLPMQGSVFSSPSVEEDIPMYSPLMELDTGEGPPRLHDSLPQWMWATNVAIYSNHFAKANVHDEERPPWGWTEDGAEVESSLCSKITSLLETPLTVPRRLTIPLIEEDSWSKTYAVASVSLAPVLLSFLWSSQDDTSLQARIVAYFIGIAIGSTLGYLAFKNTEPDRPPQIYLIPWVLGGFIMSIVWFYMIANELVALLVTFGGIYGINPSILGLTVLAWGNSMGDLVSNIALSMNGGDGVQIALSGCYAGPMFNTLVGLGMSMFLGAWSKSPETYMIPEDNSLFYTLGFLIFGLIWSLVMLPRNEMRPNKVMGIGLITLYLIFVTFRLSSAMGFIPWAS
What is the function of this protein?
Membrane-localized H(+)-dependent K(+) and Na(+) transporter.
What are the official names of this protein?
Cation/calcium exchanger 4, AtCCX4, Protein CATION CALCIUM EXCHANGER 4, Protein CATION EXCHANGER 10.
What is the protein family that this protein belongs to?
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. Cation/calcium exchanger (CCX) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MATK_PANCA
Sequence: MEKFEGYSEKQKSRQQYFVYPLLFQEYIYAFAHDYGLNGAEPVEIFGCNNKKFSSLLVKRLIIRMYQQNFWINSVNQPNQDRLLDHSNYFYLEFYSQILSEGFAIVVEIPLSLGQPSCSEEKEIPKFQNLQSIHSIFPFLEDKFLHLHYLSHIEIPYPIHLEILVQLLEYRIQDVPSLHLLRFFLNYYSNWNSLITSMKSYFLFKKENKRLFRFLYNSYVSEYEFFLLFLRKQSSCLRLTSSGTFLERVHFSGKMEHFWVMYPGFFRKTIWFFMDPLIHYVRYQGKAILASKGTLLLKKKWKSYLVNFSQYFLSFWTQPQRIRLNQLTNSCFDFLGYLPSVPINTLLVRNQMLENSFLIDTRMKKFDTTVPATSLVGSLSKAQFCTGSGHPISKPVWTDLSDWDILDRFGRICRNLFHYHSGSSKKRILYRLKYILRLSCARTLARKHKSTVRTFMQRLGSVFLEEFFTEEEQVFCLMFTKTTRFSFNGSHSERIWYLDIIRINDLVNPLTLN
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y2199_THEP3
Sequence: MAKGGFPGGFNINNMIKQAQQMQEEIKKMQEELMQKTVEATAGGGMVKAVANGRKELVSIEINPDVVDKDDVETLEDLVLAAVNQALRNAEEMIASEMAKITGGLNIPGLF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Teth39_2199.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CIPKL_ARATH
Sequence: MGLFGTKKIGKYEIGRTIGEGNFAKVKLGYDTTNGTYVAVKIIDKALVIQKGLESQVKREIRTMKLLNHPNIVQIHEVIGTKTKICIVMEYVSGGQLSDRLGRQKMKESDARKLFQQLIDAVDYCHNRGVYHRDLKPQNLLLDSKGNLKVSDFGLSAVPKSGDMLSTACGSPCYIAPELIMNKGYSGAAVDVWSCGVILFELLAGYPPFDDHTLPVLYKKILRADYTFPPGFTGEQKRLIFNILDPNPLSRITLAEIIIKDSWFKIGYTPVYHQLSDSIKDNVAEINAATASSNFINAFQIIAMSSDLDLSGLFEENDDKRYKTRIGSKNTAQETIKKIEAAATYVSLSVERIKHFKVKIQPKEIRSRSSYDLLSAEVIEVTPTNCVIEISKSAGELRLYMEFCQSLSSLLTAEVS
What is the function of this protein?
CIPK serine-threonine protein kinases interact with CBL proteins.  Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity).
What are the official names of this protein?
CBL-interacting serine/threonine-protein kinase 21, SNF1-related kinase 3.4, SOS2-like protein kinase PKS23.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Protein: MKRN1_NOTEU
Sequence: MAEAAAPGTTATTSGAAAAAAVAAASPTLTPTVASQSPAAGGGGGGSGGGWTKQVTCRYFMHGVCKKGNNCRYSHDLSTSQSAMVCRYYQRGCCAYGDRCRYEHTKPLKREEVTAANLAAKSDLPASSSLPALVEPLAEVSTGEAESVNSNFAAAGAGGEDWVNAIEFVPGQPYCGRAAPSCTEAPLQGMVIEEELEKQQTNVEMKKQLCPYAAVGECRYGENCVYLHGDACDMCGLQVLHPVDAAQRSQHIKSCIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLIQKYKEAMSNKPCRYFDEGRGSCPFGGNCFYKHAYPDGRREEPQRQKVGTSNRYRAQRRNRFWELIEERESSNPFDNDEDEVVTFELGEMLLMLLAAGGDDDLTDPEDEWDLFHDELEDYYDLDL
What is the function of this protein?
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.  These substrates include FILIP1, p53/TP53, CDKN1A and TERT.  Keeps cells alive by suppressing p53/TP53 under normal conditions, but stimulates apoptosis by repressing CDKN1A under stress conditions.  Acts as a negative regulator of telomerase.  Has negative and positive effects on RNA polymerase II-dependent transcription.
What are the official names of this protein?
E3 ubiquitin-protein ligase makorin-1, RING-type E3 ubiquitin transferase makorin-1.
Protein: RLMKL_SALAR
Sequence: MNSLFASTARGLEELLKTELEKLGAVECQVVQGGVHFQGDTRLIYQSLMWSRLASRIILPMGECKVYSDLDLYLGVQAINWTEIFNPGATFAVHFSGLNDTIRNSQYGAMKVKDAIVDAFTRKNLPRPNVDRESPDLRINVWLNKETASIALDLSGDGLHLRGYRDRAGLAPIKETLAAAIVMRSGWQPGTPLLDPMCGSGTLLIEAAMWATDRAPGLHRGHWGFSGWAQHDETIWQEVKAEAQTRARKGLAEYSSHFYGSDSDARVIERARSNARRAGIGELITFEVKDVAQLSNPLPKGPYGTVISNPPYGERLDSEPALIALHSLLGRIMKNQFGGWNLSLFSASPDLLGSLQLRADKQFKAKNGPLDCVQKNYHIAETTADSKPATVAEDYANRLRKNLKKLEKWARQEGIECYRLYDADLPEYNVAVDRYGDWAVIQEYAPPKTVDAQKARQRLFDIIAATLSVLGIPPNKLVLKTRERQKGKNQYQKMSEKGEFLEVSEYNARLWVNLTDYLDTGLFLDHRIARRMLGEMSQGKDFLNLFSYTGSASVHAGLGGARSTTTVDMSRTYLEWAERNLRLNGLSGRAHRLIQADCLGWLREANEQFDLIFIDPPTFSNSKRMEASFDVQRDHVALMKDLKRLLRKGGTIMFSNNKRGFRMDLEGLAELGLTAQEITQKTLSPDFARNRQIHNCWLICAA
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIMA1_SERMA
Sequence: MKKVLLPLAALVLSATASNAMAANGTVKFTGEIKQSTCQVTSDTQNKEVYLGTYPTSAFPTVGSKSASKAFQISLEKCDAGDYSLRFDGNTVAGNPDLLSVSNVGGTGAAATGVGIEITDNNGKPFAIGDGSNINDDVAKVTIAADGKATFNLQARYRSFDSNVTAGLANATSPFTIEYK
What is the function of this protein?
Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0. 5-1. 5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs.
What are the official names of this protein?
Type-1 fimbrial protein subunit.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.