PharMolix/UniProtQA huggingface dataset:
Protein: EPMA_ECO8A
Sequence: MSETASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEIDPLSADKTQLREVAAKLDLSNVADTEEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPASQASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQHPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA
What is the function of this protein?
With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P) on 'Lys-34'.  Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of EF-P 'Lys-34'.
What are the official names of this protein?
Elongation factor P--(R)-beta-lysine ligase, EF-P--(R)-beta-lysine ligase, EF-P post-translational modification enzyme A, EF-P-lysine lysyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
Protein: LEPA_ERYLH
Sequence: MTDLSKIRNFSIIAHIDHGKSTLADRLIQVCGGLTAREMSEQVLDNMDIEKERGITIKAQTVRLNYTASDGETYELNLMDTPGHVDFAYEVSRSLAACEGALLVVDAAQGVEAQTLANVYQSIEHDHEIVPVINKIDLPAAEPEQVRAEIEDIIGLDASEAVMTSAKSGIGIEDVLEAIVAKIPPPEGDRDAPLKASLVDSWYDPYLGVVILVRVIDGVLTKGLNVRFMQGGTQHLIDRVGCFTPKRVDLPEIGPGEIGFITAQIKEVEQARVGDTITTVKNGAPEPLKGYKEVQPVVFCGLFPVDAADFEKLRESIGKLRLNDASFSYEMESSAALGFGFRAGFLGLLHLEIIQERLSREYDLDLITTAPSVVYTVHLAHTKTEDAKVIEIHNPADWPDVNRIDVIEEPWIKATIYTPDDYLGAILKLCQDRRGIQTNLTYVGGASTLRAQVTYDLPLNEVVFDFYDRLKSISRGYASFDYEQIGSREGDLVKMNILVNNEPVDALSLIVHRSVAEERGRGMCERLKDLIPRHLFKIPIQAAIGGKIIARETIAALRKDVTAKCYGGDISRKKKLLEKQKKGKARMREYGNVSIPQEAFIAALRMGEE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: EFTU_MESH7
Sequence: MAVVKTTGKKDFDRSKEHINIGTIGHVDHGKTTLTAAISTVLAKKGLAEAKDYASIDAAPEEKARGITINTAHIEYSTDKRHYAHVDCPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTREHILLSKQVGVPKMVVFLNKIDLLEGEEEMVDLVEVEIRELLSSYDFDGDNTPIIRGSARGALEGKPEWEAKVLELMDAVDSYIDSPVREMDKPFLMAVEDVFTITGRGTVATGKVERGQVKLNEEVEIVGYREEPKKTVITGIEMFNKNLQTAMAGDNAGVLLRGVDRKDIERGQVIAKPKTIIPHTKFKAAIYALKKEEGGRHTPFFKNYKPQFYFRTTDVTGGIEFEPGREMVIPGDNVDLTVELIAPIAVEQGTKFSIREGGRTVGAGTVTEIIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTRD_NEIMB
Sequence: MISVEHVSKRYLTRQGWRTVLHDISFKMEKGEKIGILGRNGAGKSTLIRLISGVEPPTTGEIKRTMSISWPLAFSGAFQGSLTGMDNLRFICRIYNVDIDYVKAFTEEFSELGQYLYEPVKRYSSGMKARLAFALSLAVEFDCYLIDEVIAVGDSRFADKCKYELFEKRKDRSIILVSHSHSAMKQYCDNAMVLEKGHMYQFEDMDKAYEYYNSLP
What is the function of this protein?
Putative ATP-binding protein, and an energy-coupling component of capsule polysaccharide export apparatus.
What are the official names of this protein?
Capsule polysaccharide export ATP-binding protein CtrD, Capsular-polysaccharide-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PDFR_DROME
Sequence: MTLLSNILDCGGCISAQRFTRLLRQSGSSGPSPSAPTAGTFESKSMLEPTSSHSLATGRVPLLHDFDASTTESPGTYVLDGVARVAQLALEPTVMDALPDSDTEQVLGNLNSSAPWNLTLASAAATNFENCSALFVNYTLPQTGLYCNWTWDTLLCWPPTPAGVLARMNCPGGFHGVDTRKFAIRKCELDGRWGSRPNATEVNPPGWTDYGPCYKPEIIRLMQQMGSKDFDAYIDIARRTRTLEIVGLCLSLFALIVSLLIFCTFRSLRNNRTKIHKNLFVAMVLQVIIRLTLYLDQFRRGNKEAATNTSLSVIENTPYLCEASYVLLEYARTAMFMWMFIEGLYLHNMVTVAVFQGSFPLKFFSRLGWCVPILMTTVWARCTVMYMDTSLGECLWNYNLTPYYWILEGPRLAVILLNFCFLVNIIRVLVMKLRQSQASDIEQTRKAVRAAIVLLPLLGITNLLHQLAPLKTATNFAVWSYGTHFLTSFQGFFIALIYCFLNGEVRAVLLKSLATQLSVRGHPEWAPKRASMYSGAYNTAPDTDAVQPAGDPSATGKRISPPNKRLNGRKPSSASIVMIHEPQQRQRLMPRLQNKAREKGKDRVEKTDAEAEPDPTISHIHSKEAGSARSRTRGSKWIMGICFRGQKVLRVPSASSVPPESVVFELSEQ
What is the function of this protein?
Receptor for PDF, a neuropeptide controlling circadian behavioral rhythms.  Probably regulates circadian behavioral rhythms through coordination of activities of clock neurons.  PDF-binding results in the elevation of cAMP synthesis.  Plays a role in sleep regulation and regulates the state transition from sleep to wake (PubMed:19038223, PubMed:19230663).
What are the official names of this protein?
PDF receptor, Pigment-dispersing factor receptor, Protein groom-of-PDF.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: 3MGH_CORJK
Sequence: MDRSAQRIDFTQPADVVAPLLLGAVLRHGGVAIELTEVEAYLGTADEASHAFNGPTPRCEVMFGPPQHLYVYASYGIHRAGNLVCSPDGEAGGVLLRAGKIIEGLDIARARRGSKPADEALARGPGNLGAALGLNLDLNGSAVDQVFSGAGDSSPTSAPFTLTPRTAIPEITRGKRIGISKNADALLRFWVPGDRSVSSPRGRQLGTPLRASS
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: RBSD_SHIFL
Sequence: MKKGTVLNSDISSVISRLGHTDTLVVCDAGLPIPKSTTRIDMALTQGVPSFMQVLGVVTNEMQVEAAIIAEEIKQHNPQLHETLLTHLEQLQKHQGNTIEIRYTTHEQFKQQTAESQAVIRSGECSPYANIILCAGVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLN12_ORYSJ
Sequence: MANLTDLVNLNLSDCSDKIIAEYIWVGGSGIDLRSKARTVKGPITDVSQLPKWNYDGSSTGQAPGEDSEVILYPQAIFKDPFRRGDNILVMCDCYTPQGEPIPTNKRHSAAKIFSHPDVVAEVPWYGIEQEYTLLQKDVNWPLGWPVGGFPGPQGPYYCAAGAEKAFGRDIVDAHYKACIYAGINISGINGEVMPGQWEFQVGPSVGIAAADQVWVARYILERVTEVAGVVLSLDPKPIPGDWNGAGAHTNFSTKSMREPGGYEVIKKAIDKLALRHKEHIAAYGEGNERRLTGRHETADINTFKWGVANRGASIRVGRDTEKEGKGYFEDRRPASNMDPYVVTGMIAETTLLWKQN
What is the function of this protein?
High-affinity glutamine synthetase involved in ammonium assimilation (Probable).  Plays an important role in the primary assimilation of ammonium taken up by roots (PubMed:23509111).  Plays a role in maintaining nitrogen metabolic balance during ammonium assimilation, thus controlling plant growth and development (PubMed:24743556).  Reassimilates ammonium generated during lignification within developing tillers, which is probably required for the outgrowth of axillary buds (PubMed:25429996).  Required for nitrogen-dependent biosynthesis of cytokinin (PubMed:28186255).  Active cytokinin in axillary bud meristem is required for axillary bud outgrowth and necessary for tillering (PubMed:28186255).
What are the official names of this protein?
Glutamine synthetase cytosolic isozyme 1-2, Glutamate--ammonia ligase GLN1;2, OsGLN1;2, Glutamine synthetase root isozyme, OsGS1;2.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IRF3_MOUSE
Sequence: METPKPRILPWLVSQLDLGQLEGVAWLDESRTRFRIPWKHGLRQDAQMADFGIFQAWAEASGAYTPGKDKPDVSTWKRNFRSALNRKEVLRLAADNSKDPYDPHKVYEFVTPGARDFVHLGASPDTNGKSSLPHSQENLPKLFDGLILGPLKDEGSSDLAIVSDPSQQLPSPNVNNFLNPAPQENPLKQLLAEEQWEFEVTAFYRGRQVFQQTLFCPGGLRLVGSTADMTLPWQPVTLPDPEGFLTDKLVKEYVGQVLKGLGNGLALWQAGQCLWAQRLGHSHAFWALGEELLPDSGRGPDGEVHKDKDGAVFDLRPFVADLIAFMEGSGHSPRYTLWFCMGEMWPQDQPWVKRLVMVKVVPTCLKELLEMAREGGASSLKTVDLHISNSQPISLTSDQYKAYLQDLVEDMDFQATGNI
What is the function of this protein?
Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses (PubMed:15800576).  Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters (PubMed:15800576).  Acts as a more potent activator of the IFN-beta (IFNB) gene than the IFN-alpha (IFNA) gene and plays a critical role in both the early and late phases of the IFNA/B gene induction (PubMed:16846591, PubMed:16979567, PubMed:20049431).  Found in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA (dsRNA), or toll-like receptor (TLR) signaling, is phosphorylated by IKBKE and TBK1 kinases (PubMed:16846591, PubMed:16979567, PubMed:20049431).  This induces a conformational change, leading to its dimerization and nuclear localization and association with CREB binding protein (CREBBP) to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of the type I IFN and ISG genes (PubMed:16846591, PubMed:16979567, PubMed:20049431).  Can activate distinct gene expression programs in macrophages and can induce significant apoptosis in primary macrophages (PubMed:16846591, PubMed:16979567, PubMed:20049431).
What are the official names of this protein?
Interferon regulatory factor 3, IRF-3.
What is the protein family that this protein belongs to?
Belongs to the IRF family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion. Note=Shuttles between cytoplasmic and nuclear compartments, with export being the prevailing effect. When activated, IRF3 interaction with CREBBP prevents its export to the cytoplasm. Recruited to mitochondria via TOMM70:HSP90AA1 upon Sendai virus infection.
Protein: Y1382_STAEQ
Sequence: MHTILLVVFMIILGAIIGGVTNMIAIKMLFHPFKPYYIFRFRIPFTPGLIPKRREEIARKIGQVIEEHLITEELIRQKLNQPQSRNMIQQLIHKQISKLKNDDVTIKKIAGFLGIDVNELVDYKLTTKFLNKLNFWYESNKYRKLSEILPQSFLDQCKGQIEYITDFLCERARNYLSSEKGERDIYELLDTFFNEKGRIIGLLQMFMTKESIADRIQHELIRLTQHPQSQKIITKVLNDEYETFKDKNLDEIIKEQQFKNYSQLVLNELKTYLNLKDKTERPIKQVVPQFIQFLEDDTSKRMTDFIIKGTSKHLTNIMKKINLRQLVEEQINTFDLKYIENLIIDIANKELKLIMTLGFILGGIIGFFQGVIAIFV
What are the official names of this protein?
UPF0754 membrane protein SERP1382.
What is the protein family that this protein belongs to?
Belongs to the UPF0754 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y066_SIFVH
Sequence: MRKLRADVSKVKVLSEIPSGAKLLWESNELALYYTYNATQGEVDWILVNRTSDKKYVSLLRGAELIYNNNVVTVPSYVFGNAFADVYFANGLSNYINDLNNIPLYSLAVLRDSSGKNIVGFVFSLPPNSMIEVPEYGFVNLQKIWGQLLEVYPGNLNLYVIIYDYNEIIEYEQESGVNVQSPPDPYAVFSYQFSISELGAIMTPRVIIEIPQSDVNFANTLIADFKKFVSSIKHML
What are the official names of this protein?
Uncharacterized protein 66.
Protein: SECG_METBF
Sequence: MAKKSGSGLQSSAGLMRYYEADKNAVQVQPKVVLIVGAIVGIAVLFLSAVNGFWP
What is the function of this protein?
Involved in protein export.  The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
What are the official names of this protein?
Preprotein translocase subunit SecG, Protein transport protein Sec61 subunit beta homolog.
What is the protein family that this protein belongs to?
Belongs to the SEC61-beta family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: FAC17_MYCTU
Sequence: MTPTHPTVTELLLPLSEIDDRGVYFEDSFTSWRDHIRHGAAIAAALRERLDPARPPHVGVLLQNTPFFSATLVAGALSGIVPVGLNPVRRGAALAGDIAKADCQLVLTGSGSAEVPADVEHINVDSPEWTDEVAAHRDTEVRFRSADLADLFMLIFTSGTSGDPKAVKCSHRKVAIAGVTITQRFSLGRDDVCYVSMPLFHSNAVLVGWAVAAACQGSMALRRKFSASQFLADVRRYGATYANYVGKPLSYVLATPELPDDADNPLRAVYGNEGVPGDIDRFGRRFGCVVMDGFGSTEGGVAITRTLDTPAGALGPLPGGIQIVDPDTGEPCPTGVVGELVNTAGPGGFEGYYNDEAAEAERMAGGVYHSGDLAYRDDAGYAYFAGRLGDWMRVDGENLGTAPIERVLMRYPDATEVAVYPVPDPVVGDQVMAALVLAPGTKFDADKFRAFLTEQPDLGHKQWPSYVRVSAGLPRTMTFKVIKRQLSAEGVACADPVWPIRR
What is the function of this protein?
Catalyzes the activation of medium/long-chain fatty acids as acyl-coenzyme A (acyl-CoA), which are then transferred to the multifunctional polyketide synthase (PKS) type III for further chain extension (PubMed:15042094, PubMed:19182784).  Also involved in steroid side-chain degradation.  Activates cholesterol metabolites with a C5 side chain, including cholate and chenodeoxycholate (PubMed:24244004).
What are the official names of this protein?
Medium/long-chain-fatty-acid--CoA ligase FadD17, FACL, Acyl-CoA synthetase, FACL17, Steroid-24-oyl-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: YBEY_RHOBA
Sequence: MMEQPSTNLTADVLIDEEAEPDLSIWFGCLETARTELAQAAIAAAAVEGCDRGSVGVRICDDATIHPINREFLQHDYPTDVISFPYELEPPMVEGELVASFETAIENASEPSNPLSPREELLLYVVHGTLHIVGHDDQSPEPRAAMRRAEIAAMKLIGIELPLSNDEDSAPEQDDSFDDDASDSSGGIMSGGVS
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IRF8_HUMAN
Sequence: MCDRNGGRRLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFKEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQKCKLGVATAGCVNEVTEMECGRSEIDELIKEPSVDDYMGMIKRSPSPPEACRSQLLPDWWAQQPSTGVPLVTGYTTYDAHHSAFSQMVISFYYGGKLVGQATTTCPEGCRLSLSQPGLPGTKLYGPEGLELVRFPPADAIPSERQRQVTRKLFGHLERGVLLHSSRQGVFVKRLCQGRVFCSGNAVVCKGRPNKLERDEVVQVFDTSQFFRELQQFYNSQGRLPDGRVVLCFGEEFPDMAPLRSKLILVQIEQLYVRQLAEEAGKSCGAGSVMQAPEEPPPDQVFRMFPDICASHQRSFFRENQQITV
What is the function of this protein?
Transcription factor that specifically binds to the upstream regulatory region of type I interferon (IFN) and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) (PubMed:25122610).  Can both act as a transcriptional activator or repressor (By similarity).  Plays a negative regulatory role in cells of the immune system (By similarity).  Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of genes (By similarity).  Required for the development of plasmacytoid dendritic cells (pDCs), which produce most of the type I IFN in response to viral infection (By similarity).  Positively regulates macroautophagy in dendritic cells (PubMed:29434592).
What are the official names of this protein?
Interferon regulatory factor 8, IRF-8, Interferon consensus sequence-binding protein, H-ICSBP, ICSBP.
What is the protein family that this protein belongs to?
Belongs to the IRF family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=In resting macrophages, localizes in the cytoplasm. Translocated in the nucleus upon IFN-gamma induction.
Protein: GLR22_ARATH
Sequence: MKNSKLFFRFLFLFFFFCLESSRGQDNGKTQVNIGVVSDVGTSYPDVAMLCINMSLADFYSSRPQFQTRLVVNVGDSKNDVVGAATAAIDLIKNKQVKAILGPWTSMQAHFLIEIGQKSRVPVVSYSATSPSLTSLRSPYFFRATYEDSSQVHAIKAIIKLFGWREVVPVYIDNTFGEGIMPRLTDSLQDINVRIPYRSVIPLNATDQDISVELLKMMNMPTRVFIVHMSSSLASTVFIKAKELGLMKPGYVWILTNGVMDGLRSINETGIEAMEGVLGIKTYIPKSKDLETFRSRWKRRFPQMELNVYGLWAYDATTALAMAIEDAGINNMTFSNVDTGKNVSELDGLGLSQFGPKLLQTVSTVQFKGLAGDFHFVSGQLQPSVFEIVNMIGTGERSIGFWTEGNGLVKKLDQEPRSIGTLSTWPDHLKHIIWPGEAVSVPKGWEIPTNGKKLRIGVPKRIGFTDLVKVTRDPITNSTVVKGFCIDFFEAVIQAMPYDVSYEFFPFEKPNGEPAGNHNDLVHQVYLGQFDAVVGDTTILANRSSFVDFTLPFMKSGVGLIVPLKDEVKRDKFSFLKPLSIELWLTTLVFFFLVGISVWTLEHRVNSDFRGPANYQASTIFWFAFSTMVFAPRERVLSFGARSLVVTWYFVLLVLTQSYTASLASLLTSQQLNPTITSMSSLLHRGETVGYQRTSFILGKLNETGFPQSSLVPFDTAEECDELLKKGPKNGGVAAAFLGTPYVRLFLGQYCNTYKMVEEPFNVDGFGFVFPIGSPLVADVSRAILKVAESPKAVELEHAWFKKKEQSCPDPVTNPDSNPTVTAIQLGVGSFWFLFLVVFVVCVLALGKFTFCFLWKTKGKDLWKEFLKRDTDSYINDIEKCLCSQEMPENSNKATNQTNYGMELRVRNIVQVNQTDPDCL
What is the function of this protein?
Glutamate-gated receptor that probably acts as non-selective cation channel.  May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells.
What are the official names of this protein?
Glutamate receptor 2.2, Ligand-gated ion channel 2.2.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DNAJ_ACTP2
Sequence: MAKKDYYEVLGLQKGASENDIKRAYKRLASKHHPDKNQGSKDAEEKFKEINEAYEVLGDAEKRAAYDQYGHAAFEQGGGAGGFGGGFGGGGFGGFEDIFSEMFGGGFGGGGRRNHVVRGDDLRYDIEISLEEAVKGCKKDIRISTLAECDTCHGSGAEKGSKVETCSHCHGSGRIRRQQGFFVTEAVCPSCHGSGKKIEKPCKSCHGDGRVQKAKNLSVTIPAGVDTGNQLRLSGEGAAGENGAPAGDLYVVIHVREHDIFERDGSNLYCEVPISFTMAALGGEIEVPTLDGKLKLKIPAETQTGKLFRVRGKGVASPRGGYAGDLICKVVVETPVALNDEQKDLLRKLEESLAGKSKHRPQQESFLDSVKNFFSNLGKH
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTGA_CHESB
Sequence: MEAERRPGPVRRRRRSGLAGRFANRLVRAAVLVAIVPLVLTLIYCLPFVHPVSTLMLADLATLRGYERQWTPLEEAGRNVIHSVMMSEDGQFCSHRGIDLGELKAAINEALSGERTRGASTIPMQTVKNLYLWPGRSFLRKAIEAPLAIYLDAVMPKHRIMEIYLNIAEWGPGIYGVEAAAQHYFGRPSRDLSRREAALLAVTLPNPSERNPAQPSAALRRLASVVEARAQRAGGYVGCLGST
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SYT_STAAE
Sequence: MEQINIQFPDGNKKAFDKGTTTEDIAQSISPGLRKKAVAGKFNGQLVDLTKPLETDGSIEIVTPGSEEALEVLRHSTAHLMAHAIKRLYGNVKFGVGPVIEGGFYYDFDIDQNISSDDFEQIEKTMKQIVNENMKIERKVVSRDEAKELFSNDEYKLELIDAIPEDENVTLYSQGDFTDLCRGVHVPSTAKIKEFKLLSTAGAYWRGDSNNKMLQRIYGTAFFDKKELKAHLQMLEERKERDHRKIGKELELFTNSQLVGAGLPLWLPNGATIRREIERYIVDKEVSMGYDHVYTPVLANVDLYKTSGHWDHYQEDMFPPMQLDETESMVLRPMNCPHHMMIYANKPHSYRELPIRIAELGTMHRYEASGAVSGLQRVRGMTLNDSHIFVRPDQIKEEFKRVVNMIIDVYKDFGFEDYSFRLSYRDPEDKEKYFDDDDMWNKAENMLKEAADELGLSYEEAIGEAAFYGPKLDVQVKTAMGKEETLSTAQLDFLLPERFDLTYIGQDGEHHRPVVIHRGVVSTMERFVAFLTEETKGAFPTWLAPKQVQIIPVNVDLHYDYARQLQDELKSQGVRVSIDDRNEKMGYKIREAQMQKIPYQIVVGDKEVENNQVNVRQYGSQDQETVEKDEFIWNLVDEIRLKKHR
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_LACCB
Sequence: MRTPFIAGNWKMNKNPKETQEFLDGVKGKLPDASKVETVIGAPAIDLTTLVAGAEGTPLKTAAENCYFEDEGAFTGETSPKALKEMNVDYVIIGHSERRGYFHETDEDINKKAKAIFKNNLLPIICCGESLAQREAGQTEDWVASQIEAALAGLSADQVKVSVLAYEPIWAIGTGKTATADQAQEVVAHIRATVEKLYNKDTADAVRILYGGSVKPANVKELMAKPDIDGGLVGGASMDPESFIALANYQD
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.