PharMolix/UniProtQA huggingface dataset:
Protein: ILVD_BUCAI
Sequence: MPKYRSFTTTQGRNMSGARSLWRATGMTEKDFTKPIIAVVNSFSQFVPGHIHLQEVGKLICGEIQKSGGVAKEFNTIAIDDGIAMGHSGMLYSLPSRELIADSIEYVVNAHCADAMICISNCDKITPGMLMASLRLNIPSVFISGGPMEAGKIQKNNKTIKIDLVDAIINGGKSHISDDFIKDIEASACPTCGSCSGMFTANSMNCLTEAIGLALPGNGTLLATHIDRKNLFIKSAQIIVKITEDYYKKNNTNVLPRNIANKESFENAMMLDIAMGGSTNTILHLLAAAQEAKVDFKMSNINKLSKKIPHICKVAPSTSLYHVEDVHRAGGVMGILGELNRFNLLHKNTRNILQLNLEETLDEYDIFSTNNPDVINMFQAGPGGIRTTKAYSQNFRWTRLDYDRKNGCIRSCKHAYSQDGGLAILYGNLAKNGCIIKTAGIDAKNYIFSGVAKVYESQEEAASSILNGEIISGDIIVIRYEGPKGGPGMQEMLYPTTYLKSMNLDKTCALITDGRFSGGTSGISIGHISPEAANKGIIALVKNGDIININIPERTIHLNITEKELSHRILQEESKGPLSYKPHSRKRYISSALKAYAFFSTSADQGAVRDYKKISNI
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: ACCA_CUPTR
Sequence: MKTTFLDFEQPIAELEAKIEELRFVQDDSAVDISEEISRLAGKSQQLTKDIYANLTPWQVAQIARHPQRPYTLDYVREIFTDFHELHGDRTFADDLSIIGGLARFNGQSCMVIGHQKGRDTKERAMRNFGMPKPEGYRKAKRLMELADKFGLPIFTFVDTPGAFPGIDAEERGQSEAIGHNLYVMAGLRVPLIATIIGEGGSGGALAIAVGDVVQMLQFATYAVISPEGCASILWKTAEKAPEAAEALGLTAHRLKALGLIDKIVSEPLGGAHRDYKGMAALLKRSLAESLRQFQGMSVKELQARRYERLLAYGKFKETGAQD
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_PROMS
Sequence: MIENQSDNIDNKENDLSDQDNALENVSSAQELTTENNELSSQKTEEINTEELKNSISNNDARLEQLEKEHETLKNQYVRISADFDNFRKRQSRDQDDLKIQLVSKTLTAILPIVDNFERARQQLKPESEEAQSLHRSYQGLYKQLVEVLKQQGVSPMRVVGQQFDPSLHEAVLREPSEKFEEDFIIEELQRGYHLEGKVLRHALVKVSMGPGKQNSQEEVEKDKVEGDIDSEENTSEDV
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDPK1_ARATH
Sequence: MLAMEKEFDSKLVLQGNSSNGANVSRSKSFSFKAPQENFTSHDFEFGKIYGVGSYSKVVRAKKKETGTVYALKIMDKKFITKENKTAYVKLERIVLDQLEHPGIIKLYFTFQDTSSLYMALESCEGGELFDQITRKGRLSEDEARFYTAEVVDALEYIHSMGLIHRDIKPENLLLTSDGHIKIADFGSVKPMQDSQITVLPNAASDDKACTFVGTAAYVPPEVLNSSPATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRIIARDIKFPNHFSEAARDLIDRLLDTEPSRRPGAGSEGYVALKRHPFFNGVDWKNLRSQTPPKLAPDPASQTASPERDDTHGSPWNLTHIGDSLATQNEGHSAPPTSSESSGSITRLASIDSFDSRWQQFLEPGESVLMISAVKKLQKITSKKVQLILTNKPKLIYVDPSKLVVKGNIIWSDNSNDLNVVVTSPSHFKICTPKKVLSFEDAKQRASVWKKAIETLQNR
What is the function of this protein?
May couple lipid signals to the activation-loop phosphorylation of several protein kinases of the so-called AGC kinase family.  Interacts via its pleckstrin homology domain with phosphatidic acid, PtdIns3P and PtdIns(3,4)P2 and to a lesser extent with PtdIns(4,5)P2 and PtdIns4P.  May play a general role in signaling processes controlling the pathogen/stress response, polar auxin transport and development.  Transphosphorylates the AGC protein kinases OXI1/AGC2-1, PK1/S6K1, PK19/S6K2 and PID resulting in their activation.
What are the official names of this protein?
3-phosphoinositide-dependent protein kinase 1, AtPDK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane-associated after cell stimulation.
Protein: DNJC8_MOUSE
Sequence: MAASGESGASGGGGSTEEAFMTFYSEVKQIEKRDSVLTSKNQIERLTRPGSSYFNLNPFEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEYVEHTVKERKKQLKKEGKPTNVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEKKNRTFLRPPKVKMEQRE
What is the function of this protein?
Suppresses polyglutamine (polyQ) aggregation of ATXN3 in neuronal cells.
What are the official names of this protein?
DnaJ homolog subfamily C member 8.
What are the subcellular locations of this protein?
Nucleus.
Protein: GSHB_BORBR
Sequence: MHVLFIIDPLPLLKAYKDSSVAMMQALQARGHTLSVALQGDLYIDAGEVRTRFAPIALRDGADLHGHDWWRETGAADEAPLARFDAVVMRKDPPFDMEYVYSTHLLEYAQQQGARVFNSGAAIRNHPEKLAITEFPDLTTPTLVTRDMGRIRAFHAAQGDVIVKPLDGMGGTGIFRLQRSEPNLNAILETLTDNGTRTIMAQRYIPEIVKGDKRILLIGGEPVPYSLARIPLAGETRGNLAAGGRGVAQPLSERDLHLARTVADRLAGRGLLLVGLDVIGDYITEVNVTSPTCFVEITEQTGFNVPEMFAVALESAAG
What are the official names of this protein?
Glutathione synthetase, GSH synthetase, GSH-S, GSHase, Glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic GSH synthase family.
Protein: HDAC4_CHICK
Sequence: MSSQSHPDGLSGRDQPVELLNPPRVNHMPSSVDVSTALPLQVAPTSVPMDLRLDHQFPMPVTEPTLREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQEMLAMKHQQELLEHQRKLEQHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVLNKKKALAHRNLNHCISSDPRFWYGKTQHSSLDQSSPPQSGVSGTYNHPVLGMYDSKDDFPLRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACNSAPGSGPSSPNNSSNNISAENGITGSVTSIQAETSLAHRLVNREGSVTQLPLYTSPSLPNITLGLPATGPSSGGSAQQDAERLAIPALQQRISLFPGTHLTPYLSTTTLERDGGTAHNPLLQHMVLLEQPTAQTPLVTGLPLHAQSLVGGERVSPSIHKLRQHRPLGRTQSAPLPQNAQALQQLVIQQQHQQFLEKHKQQFQQQQLHINKIISKPNEPARQHESHPEETEEELREHQALLEEPYSDRVSSQKEVPGLANMVQVKQEPIESDEEEAEPQQELESGQRQAEQELLFRQQALLLEQQRIHQLRNYQASLEAAGMPVSFGGHRPLSRAQSSPASATFPMSVQEPPTKPRFTTGLVYDTLMLKHQCTCGNTNSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVHSEAHTLLYGTNPLNRQKLDSKKLLGSLTSMFVRLPCGGVGVDSDTIWNEVHSSGAARLAVGCVIELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAIAAKLLQQRLNVSKILIVDWDVHHGNGTQQAFYNDPNVLYISLHRYDDGNFFPGSGAPDEVGTGAGVGFNVNMAFTGGLDPPMGDTEYLTAFRTVVMPIANEFAPDVVLVSSGFDAVEGHPTPLGGYNLSAKCFGYLTKQLMGLAGGRVVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRANANAVHSMEKVIEIHSKYWHSLQRYASTVGYSLVEAQKCENEEAETVTAMASLSVGVKPAEKRPDDEPMEEEPPL
What is the function of this protein?
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.  Histone deacetylases act via the formation of large multiprotein complexes (By similarity).
What are the official names of this protein?
Histone deacetylase 4, HD4.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family. HD type 2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: C98A1_SORBI
Sequence: MDASLLLSVALAVVLIPLSLALLNRLRLGRLPPGPRPWPVLGNLRQIKPIRCRCFQEWAERYGPVISVWFGSGLTVVVSTSELAKEVLKENDQQLADRPRNRSTQRFSRNGQDLIWADYGPHYIKVRKLCNLELFTPKRLEALRPIREDEVTAMVESVYRAATAPGNEGKPMVVRNHLSMVAFNNITRLAFGKRFMNANGDIDEQGREFKTIVNNGIKIGASLSVAEFIWYLRWLCPLNEELYKTHNERRDRLTMKIIEEHAKSLKESGAKQHFVDALFTLKQQYDLSEDTVIGLLWDMITAGMDTTVISVEWAMAELVRNPRVQKKLQEELDRVVGRDRVMLETDFQNLPYLQAVVKESLRLHPPTPLMLPHKASTNVKIGGYDIPKGANVMVNVWAVARDPKVWSNPLEYRPERFLEENIDIKGSDFRVLPFGAGRRVCPGAQLGINLVASMIGHLLHHFEWSLPEGTRPEDVNMMESPGLVTFMGTPLQAVAKPRLEKEELYNRVPVEM
What are the official names of this protein?
Cytochrome P450 98A1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: S10AB_HUMAN
Sequence: MAKISSPTETERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDTNSDGQLDFSEFLNLIGGLAMACHDSFLKAVPSQKRT
What is the function of this protein?
Facilitates the differentiation and the cornification of keratinocytes.
What are the official names of this protein?
Protein S100-A11, Calgizzarin, Metastatic lymph node gene 70 protein, MLN 70, Protein S100-C, S100 calcium-binding protein A11.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.
Protein: MRAZ_PSEPW
Sequence: MFRGANAVSLDAKGRLAMPSRYRDELDSRCNGQLIVTIDAVDPCLCVYPLDEWEQIEAKLRALPSLREENRRLQRLLIGNAVDLELDGSGRFLVPPRLREYAKLDKKAMLVGQLNKFQLWDEDAWNAVSAADLAAIQQPGAMPDDLRDLIL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PER5_ARATH
Sequence: MERFSLRFVLMMVSIILTSSICQAQLSPTFYDQSCRNALSKIRSSVRTAIARERRMAASLIRMHFHDCFVHGCDASILLEGTSTIESERDALPNFKSVRGFEVIDKAKSEVEKVCPGIVSCADIIAVAARDASEYVGGPKWAVKVGRRDSTAAFKALANSGELPGFKDTLDQLSGLFSKKGLNTRDLVALSGAHTIGQSQCFLFRDRLYENSSDIDAGFASTRKRRCPTVGGDGNLAALDLVTPNSFDNNYYKNLMQKKGLLVTDQVLFGSGASTDGIVSEYSKNRSKFAADFATAMIKMGNIEPLTGSNGEIRKICSFVN
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase 5, Atperox P5.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: M3J_CONTE
Sequence: CCDDSECSTSCWPCCY
What are the official names of this protein?
Conotoxin tx3j.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ARGJ_YEAS7
Sequence: MRISSTLLQRSKQLIDKYALYVPKTGSFPKGFEVGYTASGVKKNGSLDLGVILNTNKSRPSTAAAVFTTNKFKAAPVLTSKKVLETARGKNINAIVVNSGCANSVTGDLGMKDAQVMIDLVNDKIGQKNSTLVMSTGVIGQRLQMDKISTGINKIFGEEKFGSDFNSWLNVAKSICTTDTFPKLVTSRFKLPSGTEYTLTGMAKGAGMICPNMATLLGFIVTDLPIESKALQKMLTFATTRSFNCISVDGDMSTNDTICMLANGAIDTKEINEDSKDFEQVKLQVTEFAQRLAQLVVRDGEGSTKFVTVNVKNALHFEDAKIIAESISNSMLVKTALYGQDANWGRILCAIGYAKLNDLKSLDVNKINVSFIATDNSEPRELKLVANGVPQLEIDETRASEILALNDLEVSVDLGTGDQAAQFWTCDLSHEYVTINGDYRS
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: DUSB_ECOLI
Sequence: MRIGQYQLRNRLIAAPMAGITDRPFRTLCYEMGAGLTVSEMMSSNPQVWESDKSRLRMVHIDEPGIRTVQIAGSDPKEMADAARINVESGAQIIDINMGCPAKKVNRKLAGSALLQYPDVVKSILTEVVNAVDVPVTLKIRTGWAPEHRNCEEIAQLAEDCGIQALTIHGRTRACLFNGEAEYDSIRAVKQKVSIPVIANGDITDPLKARAVLDYTGADALMIGRAAQGRPWIFREIQHYLDTGELLPPLPLAEVKRLLCAHVRELHDFYGPAKGYRIARKHVSWYLQEHAPNDQFRRTFNAIEDASEQLEALEAYFENFA
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.
What are the official names of this protein?
tRNA-dihydrouridine synthase B.
What is the protein family that this protein belongs to?
Belongs to the Dus family. DusB subfamily.
Protein: DRE1B_ORYSI
Sequence: MEVEEAAYRTVWSEPPKRPAGRTKFRETRHPVYRGVRRRGGRPGAAGRWVCEVRVPGARGSRLWLGTFATAEAAARAHDAAALALRGRAACLNFADSAWRMPPVPASAALAGARGVRDAVAVAVEAFQRQSAAPSSPAETFADDGDEEEDNKDVLPVAAAEVFDAGAFELDDGFRFGGMDAGSYYASLAQGLLVEPPAAGAWWEDGELAGSDMPLWSY
What is the function of this protein?
Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'.  Binding to the C-repeat/DRE element mediates high salinity- and dehydration-inducible transcription.  Confers resistance to high salt, cold and drought stress (By similarity).
What are the official names of this protein?
Dehydration-responsive element-binding protein 1B, Protein DREB1B.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SSTT_CROS8
Sequence: MTTQSQGGGLLHRLAQGSLVKQILVGLVLGILLAWLSKPAAIAVGLLGTLFVGALKAVAPVLVLMLVMASIANHKHGQKTNIRPILWLYLLGTFSAALTAVLFSFLFPSTLHLVAGATDITPPTGIVGVLRDLLLSMVANPIDALLKGNYIGILVWAVGLGFALRHGNDTTKNLVNDMSDAVTFMVKLVIRFAPIGIFGLVASTLATTGFDTLWGYAQLLMVLIGCMFLVALVINPLIVFAKIRRNPYPLVFACLRESGVTAFFTRSSAANIPVNMALCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGIAVDVPTALLLSVVASLCACGASGVAGGSLLLIPLACNMFGIPNDIAMQVVAVGFIIGVLQDSCETALNSSTDVLFTAAACQAEDARLASHALRN
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KPRS1_LACPL
Sequence: MSEQYFDPKLKIFALNSNKPLAEKIADAVGVKLGKTSVDRFSDGEIRINIEESIRGDQVYIIQSTSAPVNDNLMELLIMIDALRRASAKTINVVIPYYGYARQDRKARSREPITAKLVANMLETAGATRILALDLHAAQIQGFFDIPLDHLMGAPLLADYFLNHHLDENAVVVSPDHGGVTRARKLAEFLKAPIAIIDKRRPRANVAEVMNIIGDVKGKRAIMIDDMIDTAGTITLGAQALVDAGATEVYASCTHPVLSGPAIERIEKSPIKKLVVTDSIELPAAKRIDKIEQVSVGQLMGQAIKFIHENKPVSPLFKNRFHNEEN
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase 1, RPPK 1, 5-phospho-D-ribosyl alpha-1-diphosphate synthase 1, Phosphoribosyl diphosphate synthase 1, Phosphoribosyl pyrophosphate synthase 1, P-Rib-PP synthase 1, PRPP synthase 1, PRPPase 1.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_LEPBJ
Sequence: MFQGVYTAIITPFKNDKIDYDSYNKLLEKQIKAGVNGVVPCGTTGESPTLSHTEHAELIRETVKAVQGKIQVVAGTGSNSTREAIELTEAACKDSVDGILSVNPYYNKPTQEGLFQHFQAVAEHSSVPVMLYNIPGRTSINLQPETVFRLSEIKRIRSMKEATGDLGQMGKLISLVGNKMTVLSGDDNLTLPLLAIGGVGVVSVVSNLFPKAMVEMVKYFQDGKVIEARKIHYDFIEAFALAFMETNPIPIKAAMSWFGHCEPEIRLPLTRLSQNETSVKFKKALEVLKEKGYE
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFB_STRMK
Sequence: MTKSELIEILARRQAHLKADDVDLAVKSLLEMMGGSLSAGDRIEIRGFGSFSLHYRPPRLGRNPKTGESVALPGKHVPHFKPGKELRERVSSVLPLDADPA
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: GUF1_THAPS
Sequence: MKFIHLAMTLAYSLPHIVDAFSTLSHQRIRTSNVGVSSIFTNSQRITTFSATPTTRRTTSLFSTTENKKSSELVSNQDLGLGTSGFSTSRIRNFSIIAHIDHGKSTLADRLLESTQTVAARDMAAQLLDNMDLERERGITIKLQAARVLYKSEVDGEMYILNLIDTPGHVDFSYEVSRSLAACEGALLVVDASQGVEAQTLANVYLALENNLEIIPVLNKIDLPAADPDRVAEEIEETIGIDCSDAVRASAKSGIGINDILESIVKNVPPPQPDTGGPFRALIFDSLFDPYRGVIVFFRVVDGAVKKGQKVRFLASKAEHDVTEVGIMQPNQVQVDCLRAGEVGYLCGSIKDVLDARVGDTITLSSEYKAAAAKLDPKSEEDPITPLPGYSESIPMVYCGIFPVDADQYENLRDALGKLRLNDAAISYEPETSGAMGFGFRCGFLGLLHMDVIRERLEREFDLDLIVTAPSVVYRVEKGEGDSKTVEIVDAPSKMPEILREMKVMEPYVRMEILTPSEYNGQIIELGQERRGILKDINYLTPTRSTIVYEVPLAEVITDFFDQLKSRTQGYASMEYQLIEYREGDLVRLDVKINYEDAPPLATIVHVDAAQTVGRRLVASLKELIPRQMFKVPIQACIGVKVIASASISPMRKDVLAKCYGGDLSRKKKLLQKQAKGKKRMKAMGKVNVPQEAFMAVIKLNKSAGD
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1 homolog, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1 homolog, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: PCKG_MYCBT
Sequence: MTSATIPGLDTAPTNHQGLLSWVEEVAELTQPDRVVFTDGSEEEFQRLCDQLVEAGTFIRLNPEKHKNSYLALSDPSDVARVESRTYICSAKEIDAGPTNNWMDPGEMRSIMKDLYRGCMRGRTMYVVPFCMGPLGAEDPKLGVEITDSEYVVVSMRTMTRMGKAALEKMGDDGFFVKALHSVGAPLEPGQKDVAWPCSETKYITHFPETREIWSYGSGYGGNALLGKKCYSLRIASAMAHDEGWLAEHMLILKLISPENKAYYFAAAFPSACGKTNLAMLQPTIPGWRAETLGDDIAWMRFGKDGRLYAVNPEFGFFGVAPGTNWKSNPNAMRTIAAGNTVFTNVALTDDGDVWWEGLEGDPQHLIDWKGNDWYFRETETNAAHPNSRYCTPMSQCPILAPEWDDPQGVPISGILFGGRRKTTVPLVTEARDWQHGVFIGATLGSEQTAAAEGKVGNVRRDPMAMLPFLGYNVGDYFQHWINLGKHADESKLPKVFFVNWFRRGDDGRFLWPGFGENSRVLKWIVDRIEHKAGGATTPIGTVPAVEDLDLDGLDVDAADVAAALAVDADEWRQELPLIEEWLQFVGEKLPTGVKDEFDALKERLG
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1300_VIBPA
Sequence: MIKDRFLQLIQLLISLFLIMGALGIGITIQKFTGVSVPGSVIGMLVLFFSMTLGLVKVDWVKPGATLFIRYMILLFVPISVGLMQHFDMLLANALPIIASAVGGSLIVLVSLAWLLDYLLKEKH
What are the official names of this protein?
UPF0299 membrane protein VP1300.
What is the protein family that this protein belongs to?
Belongs to the UPF0299 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFTU_FERNB
Sequence: MAKEKFVRTKPHMNVGTIGHIDHGKTTLTAAITKYCSLFGWADYTPYEMIDKAPEERARGITINITHVEYQTEKRHYAHIDCPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTREHVLLARQVNVPAMIVFINKVDMVDDPELVDLVEMEVRDLLSKYEFPGDELPVIRGSALKAVEAPNDPNHPDLKAIKELLDAMDSYFPDPVREVDKPFLMPVEDVFTITGRGTVVTGRIERGVIKPGVEAEIIGMSYETKKTVITSVEMFRKELDEAMAGDNVGCLLRGVDKDEVERGQVIAKPGSITPHKKFKANIYVLKKEEGGRHTPFTKGYKPQFYIRTADVTGEIVDLPAGVEMVMPGDNVEMTIELIYPVAIEKGMRFAVREGGRTVGAGVVSEIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLK4_DROMO
Sequence: MLPYRNFGETIDEYEVQHLLGKGGFACVYKAKCLRTHQNVAIKMIDKKLIQGSGLSNRVRQEVDIHSRLKHPSVLQLYTFFQDANYVYLILELADNGELHRYMNQQMKRPFTEDEASSILRQVVDGLLYLHSHNIMHRDISLSNLLLSKDMHVKIADFGLATQLKRPDERHMTMCGTPNYISPEVVSHMSHGLPADLWSVGCMLYTLLVGRPPFDTDAVQSTLNKVVHSDYTMPSHLSYEARDLIDKLLRKNPHERISLEQVLRHPFMLKVGGSTISYTTPGSSVDCYGQSIASGDSGIVTFASNDSKNSQRLRSVEQQSMQQMLPQIQEEFGYYQENQKPKYAAFRLGSTEAVDNSDMDWQRMGPNTQKGNFLVHSTPSLAPAPVPADVKANNEHISVPPLNTLRLQPTRYKTKNAIMSIVANGEVVIEFIKCKSRMNEDRIVDICRISNDGRRIIIYQPDPGRGLPIREKPSELHANGTDNAYTYDNLPSKHWKKYVYAARFVGLVKSKTPKVTYFSKLAKCHLMENMADFEMSFYSGAKLTKSPSEGIKVYDASGALLSDHTSSEAKRLIEHSNECFAHCLSICNALELAQTGSNTCFPVTIGRRPIAEVLPTQRSESLRDTTNFMYSTPKSQQGSINFSISTISSMRSDNDLIGSQMLAAQQNVPIKRLNIQGIGTATELSHGVVQVQFYDGSVISVIPESQGGGITYTQPNGVSTHFPNHDDLPLAVRERVSQLPQVQMKLRCAPLLNGKKFDCNAINSKPTTSAPWHNRMLI
What is the function of this protein?
Serine/threonine-protein kinase that plays a central role in centriole duplication.  Able to trigger procentriole formation on the surface of the mother centriole cylinder, using mother centriole as a platform, leading to the recruitment of centriole biogenesis proteins such as sas-6.  When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase.  Centrosome amplification following overexpression can initiate tumorigenesis, highlighting the importance of centrosome regulation in cancers (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase PLK4, Polo-like kinase 4, PLK-4, Serine/threonine-protein kinase SAK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
Protein: FLGB_BUCBP
Sequence: MLDKINNDFNINKILLNLHAYRQEILASNIANANTPGHKSSDINFSKTFGKLFSNALQGKKNNLTTTSNKHISNNDNVELSNYDEQTVKNNSYVSKNNAINIDVDRINFVHNGLKYNADVVFINNKFKNIMNVLKG
What is the function of this protein?
Structural component of flagellum, the bacterial motility apparatus.  Part of the rod structure of flagellar basal body (By similarity).
What are the official names of this protein?
Flagellar basal body rod protein FlgB.
What is the protein family that this protein belongs to?
Belongs to the flagella basal body rod proteins family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: RECA_STAEQ
Sequence: MDNERQKALDTVIKNMEKSFGKGAVMKLGDNKGRRVSSTSSGSVTVDNALGVGGYPKGRIIEIYGPESSGKTTVALHAIAEVQKNGGVAAFIDAEHALDPVYAQALGVDIDNLYLSQPDHGEQGLEIAEAFVRSGAVDIVVVDSVAALTPKAEIEGEMGDTHVGLQARLMSQALRKLSGAISKSNTTAIFINQIREKVGVMFGNPETTPGGRALKFYSSVRLEVRRAEQLKQGQDIVGNRTKIKVVKNKVAPPFRVAEVDIMYGQGISKEGELIDLGVENDIVDKSGAWYSYNGDRMGQGKENVKNYLKENPQIKEEIDRKLREKLGIFDGDVDENENEDDSPKTLFDE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.