PharMolix/UniProtQA huggingface dataset:
Protein: CX7A1_ONCMY
Sequence: VDNMVPEKQKLFQAXNGIPVHLF
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 7A-liver, mitochondrial, Cytochrome c oxidase subunit VIIa-liver.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIIa family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: TREA_ECOHS
Sequence: MKSPAPSRPQKMALIPACIFLCFAALSVQAEETPVTPQPPDILLGPLFNDVQNAKLFPDQKTFADAVPNSDPLMILADYRMQQNQSGFDLRHFVNVNFTLPKEGEKYVPPEGQSLREHIDGLWPVLTRSTENTEKWDSLLPLPEPYVVPGGRFREVYYWDSYFTMLGLAESGHWDKVADMVANFAHEIDTYGHIPNGNRSYYLSRSQPPFFALMVELLAQHEGDAALKQYLPQMQKEYAYWMDGVENLQAGQQEKRVVKLQDGTLLNRYWDDRDTPRPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWMDNPQQLNTLRTTSIVPVDLNSLMFKMEKILARASKAAGDNAMANQYETLANARQKGIEKYLWNDQQGWYADYDLKSHKVRNQLTAAALFPLYVNAAAKDRANKMATATKTHLLQPGGLNTTSVKSGQQWDAPNGWAPLQWVATEGLQNYGQKEVAMDISWHFLTNVQHTYDREKKLVEKYDVSTTGTGGGGGEYPLQDGFGWTNGVTLKMLDLICPKEQPCDNVPATRPTVKSATTQPSTKEAQPTP
What is the function of this protein?
Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.
What are the official names of this protein?
Periplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SYS_BORRA
Sequence: MLDLKFIRDNLELVRENIKNRGLKLELDLLISFDDERRKLITKIGELNALRNENANAMKDNIGDSSRHYLIEKGKALKAEIMDLEERLGYLTSRLLVEHKRIPNISAPDVPVGVSEDENVVLKVSGNIPKFDFKPKDHLEIGIHLDLFDFEKAREVSGNKFYYLKNEAVFLELAMINFAFSKLKAKGFDLFITPDVAREFIVDGIGFNPRGAESNIYKIEDTDKYLVGTAEITLGGYYYNTILDLKSPLKMAGLSHCFRKEAGAAGQFSKGLYRVHQFSKVEMFCFCRSEDSDRIHNEFLELEEEIFIELEIPYRVLNVCSSDLGAPAYKKYDIEAWMPGRGENGDYGEVTSTSNCTDYQSRRLKIRYKEDGQNKFVHMINGTAIASTRTLIAILENFQDAKGGVRIPKSLVKYTGFDYISPKN
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AN32A_RAT
Sequence: MEMDKRIYLELRNRTPSDVKELVLDNCRSIEGKIEGLTDEFEELEFLSTINVGLTSISNLPKLNKLKKLELSENRISGDLEVLAEKCPNLKHLNLSGNKIKDLSTIEPLKKLENLKSLDLFNCEVTNLNAYRENVFKLLPQVMYLDGYDRDNKEAPDSDVEGYVEDDDEEDEDEEEYDEYAQLVEDEEEEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEDAAEEEGSQKRKREPDDEGQEDD
What is the function of this protein?
Multifunctional protein that is involved in the regulation of many processes including tumor suppression, apoptosis, cell cycle progression or transcription.  Promotes apoptosis by favouring the activation of caspase-9/CASP9 and allowing apoptosome formation.  In addition, plays a role in the modulation of histone acetylation and transcription as part of the INHAT (inhibitor of histone acetyltransferases) complex.  Inhibits the histone-acetyltranferase activity of EP300/CREBBP (CREB-binding protein) and EP300/CREBBP-associated factor by histone masking.  Preferentially binds to unmodified histone H3 and sterically inhibiting its acetylation and phosphorylation leading to cell growth inhibition.  Participates in other biochemical processes such as regulation of mRNA nuclear-to-cytoplasmic translocation and stability by its association with ELAVL1 (Hu-antigen R).  Plays a role in E4F1-mediated transcriptional repression as well as inhibition of protein phosphatase 2A.
What are the official names of this protein?
Acidic leucine-rich nuclear phosphoprotein 32 family member A, Leucine-rich acidic nuclear protein, LANP.
What is the protein family that this protein belongs to?
Belongs to the ANP32 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Endoplasmic reticulum. Note=Translocates to the cytoplasm during the process of neuritogenesis. Shuttles between nucleus and cytoplasm (By similarity).
Protein: MP_PASVK
Sequence: MDASSQYSALPYPQPPRVPSAAPSAGRLPWSRVGEIVIFTFVSVLALYLLWLWVLKDCILLLKAQRGRSTEELIFGPGERPPVASADGSRPVPDPSPPVRRDLDLSRV
What is the function of this protein?
Involved in the viral transport within, and between cells.
What are the official names of this protein?
Movement protein, MP.
What is the protein family that this protein belongs to?
Belongs to the mastrevirus movement protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: TKT1_VIBVU
Sequence: MPSRKHLANAIRALSMDGVQKANSGHPGAPMGMADIAEVLWRGHLNHNPSNPEWADRDRFVLSNGHGSMLIYSLLHLSGYELSIDDLKNFRQLHSKTPGHPEYGYAPGIETTTGPLGQGITNAVGMAMAEKALAAQFNKPGHDIVDHFTYVFMGDGCLMEGISHEACSLAGTLGLGKLIAFWDDNGISIDGHVEGWFSDDTPKRFEAYGWHVIPAVDGHNAEAINAAIEAAKADPRPTLICTKTIIGFGSPNKSGSHDCHGAPLGAEEIAAAREFLGWEHPAFEIPADVYAEWDAKAAGAEKEAAWNAKFDAYAAAYPTEAAELKRRLNGELPAEWEEKANQIIADLQANPANIASRKASQNALEAFGKMLPEFMGGSADLAPSNLTMWSGSKSLEANDFSGNYIHYGVREFGMTAIMNGIALHGGFVPYGATFLMFMEYARNAMRMAALMKVQNIQVYTHDSIGLGEDGPTHQPVEQIASLRLTPNMSTWRPCDQVESAVAWKLAIERKDGPSALIFSRQNLAQQPRSAEQVADIAKGGYILKDSDGKPELILIATGSEVELAVKAAEQLTAEGKKVRVVSMPATDTFDKQDAAYREAVLPSDVTARIAIEAGIADFWYKYVGFDGRIIGMTTFGESAPADQLFEMFGFTVENVVNTAKELLA
What is the function of this protein?
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
What are the official names of this protein?
Transketolase 1, TK 1.
What is the protein family that this protein belongs to?
Belongs to the transketolase family.
Protein: CAP8_ADE40
Sequence: MSKDIPTPYMWSYQPQMGLAAGASQDYSSRMNWLSAGPHMIGRVNGIRATRNQILLEQAALTSTPRRQLNPPSWPAAQVYQENPAPTTVLLPRDAEAEVQMTNSGAQLAGGARHVRFRDRPSPYSSGSIKRLIIRGRGIQLNDEVVSSSTGPRPDGVFQLGGAGRSSFTPRQAYLTLQSSSSQPRSGGIGTLQFVEEFVPSVYFNPFSGAPGLYPDDFIPNYDAVSESVDGYD
What is the function of this protein?
Structural component of the virion that acts as a cement protein on the capsid interior and which glue the peripentonal hexons and group-of-nine hexons together.
What are the official names of this protein?
Pre-hexon-linking protein VIII, Pre-protein VIII, pVIII.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae hexon-linking protein family.
What are the subcellular locations of this protein?
[Hexon-linking protein-C]: Virion. Note=Located on the inner side of the capsid shell. Present in 120 copies per virion. SUBCELLULAR LOCATION: [Pre-hexon-linking protein VIII]: Host nucleus. SUBCELLULAR LOCATION: [Hexon-linking protein-N]: Virion. Note=Located on the inner side of the capsid shell. Present in 120 copies per virion.
Protein: UGT47_CAEBR
Sequence: MMLQTSTILQLLLFLVGSVSAYNILVFSPATSKSHLISNGRIADELARAGHNVTLLEIDFLGIVDTTKSAKLVKKTIVRTPKGMQGFRNVLQGFSEIVMEDPGLWGLVEGNIMYQNAYNALCEEFLEMDDIFQELKAQNFDGFFAEQLNICGFGYAKALGIERRFLISSCPYFSHVYDYTSHPAPYASVPFVADMSPEPTYFERAQNLLNGFTCNMLFRYMHTRLSFIFRNKFGQDFPSVPEIVRNADIIFLATDEIIDFSAPTLPNLVNIGGLGVDDDTTEMEPVFEAEMKKGEKGVILFSLGTIANTSTIDKKVMESFLGIVKKFPDYHFLIRADKYDKNTKERAKGISNVFVSDWLPQPAILHHPRLRTFITHAGYNGLVEAARAGVPLITIPFMFDQNLNSRAIEKKGWGIRSDKKKLLNDPDSFEADLKEMLTNPSYTKNAHRIRDLIKSKPLGARDRFIKTTEWVIQNGGVRELLTEGRDLSIISSYNLDIIVPVLFVLLYCLIIPFFKLIGGFYYYSCFGHIESKHKLD
What are the official names of this protein?
Putative UDP-glucuronosyltransferase ugt-47, UDPGT 47.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PIPNA_HUMAN
Sequence: MVLLKEYRVILPVSVDEYQVGQLYSVAEASKNETGGGEGVEVLVNEPYEKDGEKGQYTHKIYHLQSKVPTFVRMLAPEGALNIHEKAWNAYPYCRTVITNEYMKEDFLIKIETWHKPDLGTQENVHKLEPEAWKHVEAVYIDIADRSQVLSKDYKAEEDPAKFKSIKTGRGPLGPNWKQELVNQKDCPYMCAYKLVTVKFKWWGLQNKVENFIHKQERRLFTNFHRQLFCWLDKWVDLTMDDIRRMEEETKRQLDEMRQKDPVKGMTADD
What is the function of this protein?
Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes (PubMed:10531358, PubMed:22822086, PubMed:15522822, PubMed:18636990, PubMed:14962392).  Shows a preference for PI and PC containing shorter saturated or monosaturated acyl chains at the sn-1 and sn-2 positions (PubMed:15522822, PubMed:22822086).  Preference order for PC is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 and for PI is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 > C20:3 (PubMed:22822086).
What are the official names of this protein?
Phosphatidylinositol transfer protein alpha isoform, PI-TP-alpha, PtdIns transfer protein alpha, PtdInsTP alpha.
What is the protein family that this protein belongs to?
Belongs to the PtdIns transfer protein family. PI transfer class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CLPP2_BACCZ
Sequence: MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLESQDPEKDIHIYINSPGGSITAGMAIYDTMQFIKPQVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILFLREKLNQILADRTGQPLEVLQRDTDRDNFMTAEKALEYGLIDKIFTNR
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 2, Endopeptidase Clp 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNZ_CYTH3
Sequence: MDFELFILGSSSATPSKGRYQSAQLLKIHNDYFMIDCGEAAQYQLSRYKLNHTKISHIFISHLHGDHFFGLVGLLSTMNLYGRKNPIHVFGPPGLDEIIQIQLKYSETLLQFPLHYTTLENEGSEHILDHPLVDVYTIPLEHRIRCNGFLFKEKPKSYKLNKSKLPEDLSLLEIAQLKQGIDVYDENGNVKALVREICMPALKSRSYAYCSDTKVNEQYFPYIKGVDLLYHESTFLDELADRAAKTYHTTAKQAAQVAKEAEAGKLIIGHFSSRYYDTEPFLLEASSIFKHTYLGTEGSSFYVSDRISHEDNS
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: ACCA_COXB2
Sequence: MNLDYLDFEQPIAELQAKIDELRRVGTSQEINLTEEVNKLEEKNAQLTRQIFSNLTAQQIVQLARHPLRPYTLDYIQRIFTDFNELHGDRHYSQASAIIGGLARLNGEPVMVIGHQKGRTTQEKIYRNFGMARPEGFRKALRLMKLAERFSIPVITLIDTPGAYPGIGAEERNQSEAIARNLFEMAQLKIPIICTIIGEGCSGGALAIGVGDRTLMLQYAYYSVISPEGCASILWKSAEKAGEAAEALGLTANRLHELGLIDEIIKEPLGGAHRDTDAMAEKLKKHLQANLTNLQAKSANDLLEERYRRWLSYGKD
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_RICRS
Sequence: MNSLENLILVGVIKSCHGIKGHVMLKSFTDPATKILERNLVNESGANIHIKLISQNAKGELICTFNDIATRNEAEHLKGYKIFCLRASLPELEEDEFYIADLTHLPVLNQDHKEIGKIKNILNFGAGDIIEIEFSDQTTELLPFNKEFFPIITKDYVILNYQREA
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_BORPE
Sequence: MAKRRGLALDGVLLLDKPVGLSSNHALQRAKRTVDAAKAGHTGTLDPFATGLLVCCMGRATKISGRMLEADKTYQATLQFGEETDSGDLTGHIVARAPDGFAGVEEAALRDVLSRFVGTIEQIPPMYSALKRDGKPLYEYARAGIELDRPPRQVTIRHIELLSFSGMQAQIDVACSKGTYIRTLAQDIGRALGCHAHLAALRRTHVGPFSLDRAVTLEALQAMPDAKQALLAMNELPAGLLPAT
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: YEAH_ECO8A
Sequence: MTWFIDRRLNGKNKSMVNRQRFLRRYKAQIKQSISEAINKRSVTDVDSGESVSIPTEDISEPMFHQGRGGLRHRVHPGNDHFVQNDRIERPQGGGGGSGSGQGQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKQNQQRQLTEYKTHRAGYTANGVPANISVVRSLQNSLARRTAMTAGKRRELHALEENLAIISNSEPAQLLEEERLRKEIAELRAKIERVPFIDTFDLRYKNYEKRPDPSSQAVMFCLMDVSGSMDQSTKDMAKRFYILLYLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVKERYNPAQWNIYAAQASDGDNWADDSPLCHEILAKKLLPVVRYYSYIEITRRAHQTLWREYEHLQSTFDNFAMQHIRDQDDIYPVFRELFHKQNATAKD
What are the official names of this protein?
UPF0229 protein YeaH.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: MRM2_SCHPO
Sequence: MFGSKTLFSWAAKRSKDFYRKKSKIDNFRSRAAYKLIELNSKYRFINKEDVVIDVGFAPGSWSQVAKKLVGNKGKVIGIDIQHIAPPEGVLPIYGDIRDPNTLTKLFEALRLLHEPNTNDSIDCRVVDAVISDMLHKATGIRIRDHALSMELCASALHVALTFLKSNGSFICKFYMGDEDADLQNLLKSHFRFVQVMKPKASLKESREAYFVCLERKP
What is the function of this protein?
S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of the 2'-O-methyluridine corresponding to position 2791 in S. cerevisiae 21S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA.
What are the official names of this protein?
rRNA methyltransferase 2, mitochondrial, 21S rRNA (uridine-2'-O)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GPDA_BACCR
Sequence: MTKITVVGAGSWGTALAMVLADNGHDVRIWGNRPELMDEINTKHENSRYLPGITLPSTIVAYSSLEEALVDVNTVLLVVPTKAYRDVLQEMKEIVTEPITWIHASKGIEPGTSKRISEVIEEEIPEHLIKDVVVLSGPSHAEEVGLRQATTVTSAAKRMEAAEEVQDLFMNSYFRVYTNPDIVGVELGGALKNIIALAAGITDGLGLGDNAKAALMTRGLTEIARLGRKMGGNPLTFAGLTGMGDLIVTCTSVHSRNWRAGNMLGKGHSLEEVLESMGMVVEGVRTTKAAHELAEKMEVEMPITAALYDVLFNGNNVKDAVGSLMGRVRKHEVEAIPDLL
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF1_XANAC
Sequence: MIREIIRMGDKRLLRVAPPVTNLGSAELHTLVADMFETMDAARGVGLAAPQIAVDLQLMVFGFDASERYPEAPAVPRTALANAQIEPLSEDMENGWEGCLSIPGLRAVIPRYRFIRYRGFAPDGSPIERDAEGFHARVVQHEYDNLVGRLYPSRIENFDTFGFEDVLSYDL
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase 1, PDF 1, Polypeptide deformylase 1.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: DCD_CHLCV
Sequence: MSIKEDKWIRKMALAHGMIEPFADGQVNVDAETGEKLISYGLSSYGYDLRLSREFKVFTNVYNSLVDPKHFTEDTFISITDDVCIIPPNSFALAHSVEYFRIPRNILTMCIGKSTYARCGLIVNVTPFEPEWEGYVTIEISNTTPLPAKIYANEGIAQVLFFEADEMCEVSYAERKGKYQKQQGITVPFV
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: PSA_ACIC1
Sequence: MSTPFYVSPEQIMKDRAEFARKGIARGRSNVVLQYADGILFVAENTSKALHKISEVYDRIAFAAVGRYNEFENLRVAGVRLADLTGYTYDRRDVTGRTIANAYAQTLGAIFSGATEKPYEVEIVVAEVGDTPDGDSMYRLTYDGSVAEEHGYVAMGGQAEQITAQLKDRYVENLPLGEALRLAVDVLSRASDGGEPRTLTPDQLEVAALDRTRGRRAFRRFIGAQLQELLRPTS
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PrcA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O2T27_HUMAN
Sequence: MEQSNYSVYADFILLGLFSNARFPWLLFALILLVFLTSIASNVVKIILIHIDSRLHTPMYFLLSQLSLRDILYISTIVPKMLVDQVMSQRAISFAGCTAQHFLYLTLAGAEFFLLGLMSYDRYVAICNPLHYPVLMSRKICWLIVAAAWLGGSIDGFLLTPVTMQFPFCASREINHFFCEVPALLKLSCTDTSAYETAMYVCCIMMLLIPFSVISGSYTRILITVYRMSEAEGRGKAVATCSSHMVVVSLFYGAAMYTYVLPHSYHTPEQDKAVSAFYTILTPMLNPLIYSLRNKDVTGALQKVVGRCVSSGKVTTF
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 2T27, Olfactory receptor OR1-67.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEC8_MEDTR
Sequence: MANSNPKLLVTQNPFSVFLLTFLLLITNVKSDSFSFNFPKFDTDTKSIIIDGDANTTNGVLQLTKKDQLGNPSPHSFGLSFFLGAIHLSDKQSGKVADFTTEFSFVVNPKGSQLHGDGFTFFIASLDYEFPEKSSDGGFLGLFDKESAFNTSQNSIVAVEFDSFRNEWDPQIAGNSPHIGIDINTIRSSATALWPIDRVPEGSIGKAHISYNPASKKLTALVTYLNGPVIEETAVSYTVDFAAILPEYVLVGFSGATGELAETHDILSWSFTSNL
What is the function of this protein?
May be involved in arbuscular mycorrhizal (AM) symbiosis with AM fungi.
What are the official names of this protein?
Lectin 8, MtLec8, Agglutinin LEC8.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: RS3_MYCTU
Sequence: MGQKINPHGFRLGITTDWKSRWYADKQYAEYVKEDVAIRRLLSSGLERAGIADVEIERTRDRVRVDIHTARPGIVIGRRGTEADRIRADLEKLTGKQVQLNILEVKNPESQAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRQPNVKGIRVQCSGRLGGAEMSRSEFYREGRVPLHTLRADIDYGLYEAKTTFGRIGVKVWIYKGDIVGGKRELAAAAPAGADRPRRERPSGTRPRRSGASGTTATGTDAGRAAGGEEAAPDAAAPVEAQSTES
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: EFTS_VIBC1
Sequence: MATVTAALVKELRERTGAGMMECKKALVEANADIELAIENMRKSGAAKAAKKAGNVAAEGAIIIKEENGVAVLLEVNCQTDFVAKDGNFTAFADKVALDALATKATAEELVAKFEEERVALVAKIGENINIRRVAYVEGTAIASYRHGEKIGVVVAGEGDAETLKHVAMHVAASKPEFVNPEDVPADVVAKEKEVQVEIAMNEGKPQEIAEKMVIGRMKKFTGEISLTGQAFIMEPKKSVGEMLKEKGASVATFVRLEVGEGIEKAAEMSFAEEVALAQKG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WDR89_MOUSE
Sequence: MEKIEDQFASLHIVRRSSEPKEPTYLLGIDTSKTVQADKGGLVAVLCSNGSIRIYDKETLHLLREFGGSPGLLSGVSFANSCDSVYSASTDGTVKCWDARGASEKPVQLFKGYPSCSFISFDVNCKDHVICAGAEKVDEDALLVFWDARFTSQDLSTRDPLGAYSETHSDDITQVRFHPSNPNLVVSGSTDGLVNVFDLSADKEEDALVATCNSVSSVSCIGWCGKDYKQIYCMTHDEGFCWWDLNHLDTDEPITCLNIQDVREITDVKDGHLDYLIGGLYHEKMDRLFVIGGTNTGKIHLLSCTSAGLTHVTSLHGGHAATVRSFCWNVSEDSLLTGGEDAQLLLWKPGAMEKTFTKKDSLKIASSVQQRVRVHSSDSYKKRKQQ
What are the official names of this protein?
WD repeat-containing protein 89.
Protein: NEF_SIVVT
Sequence: MGSQNSKPAHKKYSKLWQALHKTHVTRYGLLADPLIGTSSTVQEECDKALRKSLIRKQNGNMTEEERRLQEGDTWEEWSDDEEEVGFPVRPRVPLRQMTYKLAVDFSHFLKEKGGLDGIYYSDRRNKILNLYALNEWGIIDDWNAWSKGPGIRFPKCFGFCFKLVPVDLHEEAQTCERHCLVHPAQMGEDPDGISHGEILVWKFDPMLAIQYDPNREYFTDMHGLVKRK
What is the function of this protein?
Interferes with TCR signaling from the cell membrane.  Interacts with CD247/TCRZ (TCR zeta chain) and exert potent down-regulation of cell surface TCR/CD3 complexes (By similarity).
What are the official names of this protein?
Protein Nef, 3'ORF, Negative factor, F-protein.
What is the protein family that this protein belongs to?
Belongs to the lentivirus primate group Nef protein family.
What are the subcellular locations of this protein?
Host cell membrane; Lipid-anchor; Cytoplasmic side. Note=Associates with the inner plasma membrane through its N-terminal domain.
Protein: CATA3_ARATH
Sequence: MDPYKYRPSSAYNAPFYTTNGGAPVSNNISSLTIGERGPVLLEDYHLIEKVANFTRERIPERVVHARGISAKGFFEVTHDISNLTCADFLRAPGVQTPVIVRFSTVVHERASPETMRDIRGFAVKFYTREGNFDLVGNNTPVFFIRDGIQFPDVVHALKPNPKTNIQEYWRILDYMSHLPESLLTWCWMFDDVGIPQDYRHMEGFGVHTYTLIAKSGKVLFVKFHWKPTCGIKNLTDEEAKVVGGANHSHATKDLHDAIASGNYPEWKLFIQTMDPADEDKFDFDPLDVTKIWPEDILPLQPVGRLVLNRTIDNFFNETEQLAFNPGLVVPGIYYSDDKLLQCRIFAYGDTQRHRLGPNYLQLPVNAPKCAHHNNHHEGFMNFMHRDEEINYYPSKFDPVRCAEKVPTPTNSYTGIRTKCVIKKENNFKQAGDRYRSWAPDRQDRFVKRWVEILSEPRLTHEIRGIWISYWSQADRSLGQKLASRLNVRPSI
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase-3.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: FERX_MYCTU
Sequence: MGYRVEADRDLCQGHAMCELEAPEYFRVPKRGQVEILDPEPPEEARGVIKHAVWACPTQALSIRETGE
What is the function of this protein?
Ferredoxin that is the redox partner of cytochrome CYP51, a sterol 14alpha-demethylase encoded by an adjacent gene.
What are the official names of this protein?
Ferredoxin Fdx.