PharMolix/UniProtQA huggingface dataset:
Protein: NRK_MOUSE
Sequence: MAGPGSWRDKEVTDLGQLPDPTGIFSLDKAIGLGTYGRIFLGIHEKTGSLVAVKVMSARKTPLPEIGRRVRVNKYQKSVGWRYSDEEEDLRTELNLLRKYSFHKNIVTFYGAFFKLNPPGHQHQLWMVMELCAAGSVTDVVRMTRNQSLKEDWIAYICREILQGLAHLHAHQVIHRDIKGQNVLLTHDAEVKIVDFGVSAQVSRTNGRRNSFIGTPYWMAPEVIHCDEDPRCSYDYRSDVWSVGITAIEMAEGAPPLCKLQPLEALCVILREAAPKVKSSGWSRKFQNFMENCMIKNFLFRPTSGNMLLHPFVHDIKNERRVVESLTKHLTGIIQKREKKGIPVAFEGEEAAKEQYITRRFRGPSCTPELLRVPTSSRCRPLRVLHGEPPQPRWLPDQEDPQDQELQQLQKAAGVFMPLHSQDNTSKLFPKQVEVAPYLRGAAQVVMPVLVQVEAPPQVSKAAQMLKSLPTQDNKATSPEVQAPVAEGQQAQHEALETEQPKDLDQVPEEFQGQDRAPEQPRQGQAAEQQQIHNPVPEQPPEEDREPEQAEVQEEAVEPPQAEIEDKEPEVVQVHAQVLLPLLSQNRHVLLPLHLDRQLLIPVGEQNEEVPRAQAWDLEASRAVGAVQALIEGLSRDLLRAPNAFVTKPLGPLQIFLENLSTDGFYTEPEPTQKKKSKVASLRKAIAKRLRPKRFRAKALWRLEDFEFSDVETSRRRRHRRWEDIFNQHEEQLRRVENDREDDSSDNDEVFHSIQAEVQIEPHAANPAGNEVHERSAPMPCNRNRTHRVKFSPSVGEEEPSLEEAQPQQQQQQPMNIRPRNCLNPQNFQAQSDSSSEEDSPVTRRKSQSSPPYSTIDQKLLIDIHVPDGFKVGKISPPVYLTNEWVGYNALSEIFWDDWIMPTRPARPPEEDGDYVELYDADANANGDEEVANGAYEDPRDGANGHDDMNNQLDQANGYEGHGAAGYNGGDVGGNHGAAFNGPRANYPRAGILKNGHNDGRALNRGAFGVFGDNAARAFHGAAGEAGAAFGNHGANRGNGRGNRNREANGRNEENGAFGRDQHVFPEFEHEESDRGTETSDSIALEITSFDGEQNSGRPVSSTTMGFPIGRSSPRGSDFGSDISYNSPILHVYEKDFSSEVYCGSLWGVNLLLGTQSHLYLMDRSGKAEIVKLIKRRPFRQIQVVEQLNLLITISGKKNRLRVYHLSWLRNKILNNDPKSKKRQKAMRKKEEACKAIDKLIGCEHFSVLQHEETTYIAVAVKSSIHLFAWAPKSFDENTAIKVFPTRDLKPLTVDLAVGSEKTLKIFFSSANGYHIIDAESEVMSEVTLPNNNVVILPDCLGLGVMLSLNAEAASEEANEQLLKKILDVWKDIPSSVAFECTKRITGWDQKAIEVRSLQSTILENELKRRSIKKLRFLCARGDKMFFASTLSNDHSRVYLMSLGKLEELHRSYAV
What is the function of this protein?
May phosphorylate cofilin-1 and induce actin polymerization through this process, during the late stages of embryogenesis.  Involved in the TNF-alpha-induced signaling pathway.
What are the official names of this protein?
Nik-related protein kinase, Nck-interacting kinase-like embryo specific kinase, NESK, NIK-like embryo-specific kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Protein: CLPB_XYLFT
Sequence: MRMDKLTSRFQNALADAQSLAVGRDHTIIEPVHVFSVLLDQQGGSTRPLLVQAGVNVPLLRERLTEILEALPKVSGQTVNVSPSNELSRLFHRTDKLAQQHGDQFMASEWFVLAVVDDSGGLGQALRAAGAEKKKIEAAIDKLRGGETVQTENAEEQRQALEKYTIDLTARAESGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLRSKRLLSLDLGALIAGAKFRGEFEERLKGVLNDLAKNEGRVILFIDELHTMVGAGKAEGAMDAGNMLKPALARGELHCIGATTLDEYRKYIEKDAALERRFQKVFVGEPTVEDTIAILRGLKEKYALHHGVEITDPAIVAAATLSNRYITDRQLPDKAIDLMDEAASRIRMEIDSKPEELDRLERRLIQLKIQREMLKKEKDEASKQRLVDLERDIEVLDREFSDLEEVWRSEKAALQGATKIKESIEQAKLDLEAAQRRQDYAKMSEIQYGVLPALEKQLVAASQAEQHDFTLVQEKVTAEEIAEVVSRWTGIPVSKMLEGERDKLLRMEADLGRRVVGQDEAIKVVSDAVRRSRTGLSDPNRPSGSFLFLGPTGVGKTELCKALAEFLFDSQDAMVRIDMSEFMEKHSVARLIGAPPGYVGYEEGGYLTELVRRRPYSLILLDEVEKAHSDVFNILLQVLDDGRLTDGQGRTVDFRNTVIVMTSNLGSHQIQELSGDDSPEVYTQMKAAVMGVVQAHFRPEFINRLDDIVVFHPLDKAQIKQIARIQLRGLEKRLAESELKLDLDDRALELLGNVGFDPVYGARPLKRAIQSQLENALAQQILAGAFVSGDTVQVGVDGGKLVFSKV
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYO1D_MOUSE
Sequence: MAEQESLEFGKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKVLNIYGRDTVEQYKGRELYERPPHLFAIADAAYKAMKRRSKDTCIMISGESGAGKTEASKYIMQYIAAITNPSQRAEIERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLHSLHLQKSLSSYNYIRVGAQLKSSINDAAEFKVVADAMKVIGFKPEEIQTVYKILAVILHLGNLKFIVDGDTPLIENGKVVSVIAELLSTKADMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDGMFLEALNSKLGKHGHFSSRKTCASDKILEFDRDFRIRHYAGDVVYSAIGFIDKNKDTLFQDFKRLMYNSSNPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVKKLIERCGFQDDVAYGKSKIFIRTPRTLFTLEELRAQMLVRVVLFLQKVWRGTLARMRYKRTKAALTIIRYYRRYKVKSYIHEVARRFHGVKNMRDYGKHVKWPTPPKVLRRFEEALQSIFNRWRASQLIKTIPASDLPQVRAKVAAMEMLKGQRADLGLQRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHTKDNKDLIVCLFSKQPTHESRIGELVGVLVNHFKSEKRHLQVNVTNPVQCSLHGKKCTVSVETRLNQPQPDFTKNRSGFILSVPGN
What is the function of this protein?
Unconventional myosin that functions as actin-based motor protein with ATPase activity (By similarity).  Plays a role in endosomal protein trafficking, and especially in the transfer of cargo proteins from early to recycling endosomes (By similarity).  Required for normal planar cell polarity in ciliated tracheal cells, for normal rotational polarity of cilia, and for coordinated, unidirectional ciliary movement in the trachea.  Required for normal, polarized cilia organization in brain ependymal epithelial cells (By similarity).
What are the official names of this protein?
Unconventional myosin-Id.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm. Perikaryon. Cell projection, dendrite. Early endosome. Cytoplasm, cell cortex. Basolateral cell membrane. Note=Colocalizes with the actin cytoskeleton in the cell cortex close to the basolateral cell membrane (PubMed:20089841). Colocalizes with the actin cytoskeleton in the cell cortex close to the apical cell membrane (PubMed:20089841). Colocalizes with cytoplasmic puncta that are reminiscent of transport vesicles (By similarity).
Protein: RL35_COXBR
Sequence: MPKLKTNRGAVKRFKVTGSGKIKRAASNHNHMLTKKSQKRKRRLRKIHEVAPSDMRAVSEMLRD
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: AIS_SALEP
Sequence: MLAFTLRFIKNKRYFAILAGALVIIAGLTSQHAWSGNGLPQINGKALAALAKQHPVVVLFRHAERCDRSDNTCLSDSTGITVKGAQDARALGKAFSADIQNYNLYSSNTVRTIQSATWFSAGRSLTVDKKMMDCGSGIYASINTLLKKSQNKNIVIFTHNHCLTYIAKNKRGVKFDPDYLNALVMHAENGKLFLDGEFVPG
What is the function of this protein?
Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core.
What are the official names of this protein?
Lipopolysaccharide core heptose(II)-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. Ais subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: LPFE_SALTY
Sequence: MKNLHALMPACLLLTASAMAAPSNIGSAGDIHFTITIKAATCELENDSIDVNMETVVLQRPVKVGKELNQKNFSIGLKDCAYATKASVTMDGSPDPTDPSLFALDSGGATGVALKIKTSGGEQQYPSSTDSTPVEHTVWFDGTNKLNYIASYVPVKPDATVGTANATVNFSVTYE
What are the official names of this protein?
Protein LpfE.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: R7SL2_ARATH
Sequence: MNVDIDTETGSSFSITIDFGETVLQIKEKIEKSQGIPVSKQILYLDGKALEDDLHKIDYMILFESLLLRISPDADPNQSNEQTEQSKQIDDKKQEFCGIQDSSESKKLTRVMARRVHNVYSSLPAYSLDELLGPKYSATVTVGGRTNQVVQTTEQASTSGTAKEVLRDSDSPVEKKIKTNPMKFTVHVKPYQEDTKMIQVEVNADDNVEELRKELVKMQERGELNLPHEAFHLVSSELPLIETKSFKWNRVADGDTIELIREK
What is the function of this protein?
Controls phase transition from the vegetative to the reproductive state.  Involved in the maintenance of the shoot apical meristem (SAM) thus preventing inflorescence meristem (IM) formation and subsequent inflorescence stem development during flowering.  Regulates leaf and organ morphology.
What are the official names of this protein?
Ubiquitin domain-containing protein 7SL RNA2, At7SL-2, Protein ETERNALLY VEGETATIVE PHASE 1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS4_PELTS
Sequence: MARYTGSVCRLCRREGLKLYLKGDRCYTPKCAIDRRSYAPGQHGQGRKKVSEYGLQLREKQKARRIYGILESQFRRYFEKAERQPGITGENLLRLLERRLDNVIYRLGLGASRNEARQLVRHGHFTVNGRRVNIPSYLVKPGDVIAVRDQSKESPRIKELLERAADRTPPAWLEYEADQARARVAALPARDQIDAPVQEHLIVELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: TRPA_CORGB
Sequence: MSRYDDLFARLDTAGEGAFVPFIMLSDPSPEEAFQIISTAIEAGADALELGVPFSDPVADGPTVAESHLRALDGGATVDSALEQIKRVRAAYPEVPIGMLIYGNVPFTRGLDRFYQEFAEAGADSILLPDVPVREGAPFSAAAAAAGIDPIYIAPANASEKTLEGVSAASKGYIYAISRDGVTGTERESSTDGLSAVVDNIKKFDGAPIFLGFGISSPQHVADAIAAGASGAITGSAITKIIASHCEGEHPNPSTIRDMDGLKKDLTEFISAMKAATKKV
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: Y052_METJA
Sequence: MDEGILARLITFTEDVVLCIVLNDGRKMITNGKKILAGKIEGELASFILSASKEFLEDKKVGVKKFKDYDIYFERIDINKFLKSIGGEFVKNTITVSELLELIKKEDVIIVDTRSPREFKEETLPGAINIPLFLDDEHALIGKTYKQESREKAIEIATDIVEKSLKRILNEAKKLDRDKLIVVFCARGGMRSQTMALILQLLGFKVKRLIGGFKAFKHAVDK
What are the official names of this protein?
Uncharacterized protein MJ0052.
Protein: COTL1_BOVIN
Sequence: MATKIDKEACRTAYNLVRDDSSAVIWVTFKYDGSTIVPGEQGAEYQDFIQQCTDDVRLFAFVRFTTGDAMSKRSKFALITWIGENVSGLQRAKTGTDKTLVKEVVQNFAKEFVISDRKELEEDFIKNELKKAGGANYDAQTE
What is the function of this protein?
Binds to F-actin in a calcium-independent manner.  Has no direct effect on actin depolymerization.  Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis (By similarity).
What are the official names of this protein?
Coactosin-like protein.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family. Coactosin subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Nucleus.
Protein: TPRA3_MAIZE
Sequence: MTKHAAYSSEDVVAAVAAPAPAGRHFTSFQALKGAPLDCKKHAAVDLSASGAAVVGGGPWFESMKASSPRRAADAEHGDWMEKHPSALAQFEPLLAAAKGKQIVMFLDYDGTLSPIVEDPDRAVMSEEMREAVRRVAEHFPTAIVSGRCRDKVLNFVKLTELYYAGSHGMDIQGPAACRQPNHVQQAEAAAVHYQAASEFLPVIEEVFRTLTAKMESIAGARVEHNKYCLSVHFRCVREEEWNAVNEEVRSVLREYPNLKLTHGRKVLEIRPSIKWDKGKALEFLLKSLGYAGRNDVFPIYIGDDRTDEDAFKVLRNMGQGIGILVSKLPKETAASYSLSDPAEVKEFLRKLANKKGARQP
What is the function of this protein?
Removes the phosphate from trehalose 6-phosphate to produce free trehalose.  Is specific for trehalose 6-phosphate.  Does not possess activity toward glucose, sucrose or fructose 6-phosphates.  Regulates inflorescence branching.  Required to establish the correct identity and determinacy of axillary meristems in both male and female inflorescences.  May act through a sugar signal that moves into axillary meristems.  Acts upstream of RA1.  May have a transcriptional regulatory function.
What are the official names of this protein?
Trehalose 6-phosphate phosphatase RA3, Protein RAMOSA 3.
What is the protein family that this protein belongs to?
Belongs to the trehalose phosphatase family.
Protein: MIAA_VIBVY
Sequence: MTEQLPLALFLMGPTASGKTELAIRLRQRYPVELISVDSALIYKGMDIGTAKPDEREQQLAPHRLIDILDPTEAYSAADFRRDALAAMNEIVVQGKIPLLVGGTMLYFKALLEGLSPLPAANAEIRQQIEQEALTKGWSVLHDELQEIDPVSAARIHPNDPQRLSRALEVYRISGKTLTELTETKGESLPFRVKQFAIAPKERAELHRRIELRFDKMMEAGFEQEMRALYTRKDLHPDLPSIRCVGYRQMWDYLDGNCTLDEAIYRGICATRQLAKRQITWLRSWDNLTWLDSENIEQSLETLSEAIASDRDSCV
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: REML3_ARATH
Sequence: MTDAMFSSSAKPHFIKPMLPGFETYIVIPKAFYSNYLEGRQEGNAAELRSDATEITWKIKIDGRRMTKGWEEFAVAHNLQVDDILVFRHEGNLLFHVTPFGLSFCEILYSQRDEKDVKDTTGKVTRSRTVKKNGKNECSSVDTDFVVPVTASNQRVDSFYLPRGFTTSSGSSKLCNEIILIDEKDRPSTLKLRYNKSSNRFCVSRGWRAFCCRNGYRTGCFLRIILVRKGKTPVLRIFPLERDEDNIEKHSKKVKQEVEHEESVKEETNVESGKLKRDRLLQKDPKNLCSTSQDTNFVVPVTASNQRHDSFHLPKGLTTSSGLSKLCKKIIFMDQKGRSSILDLSYSISDDRFTVRRGWKAFCCRNEHKTGCFLRLILVQNGKTPVLRIFPLERYENSIAKNSKKIKQEVEYESAKEEKNLESLSLSDNSSFVVSVTVSNLSEDILHLPIRLSRSNLLDKKIHEIVLMNKEGRTWILSLKYSKYSGRFRITRGWKSFCEANGQKPGCTFLLKLHLSMTRFDQDGVAWDKK
What are the official names of this protein?
B3 domain-containing protein REM-like 3, Protein REPRODUCTIVE MERISTEM-like 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: NSG2_RAT
Sequence: MVKLNGNPGEKGAKPPSVEDGFQTVPLITPLEVNHLQLSAPEKVIVKTRTEYQPEQRNKGKFRVPKIAEFTVTILVSLALAFLACIVFLVVYKAFTYDHSCPEGFVYKHKRCIPASLDAYYSSQDPSSRSRFYTVISHYSVAKQSTARAIGPWLSAAAVIHEPKPPKTQGH
What are the official names of this protein?
Neuronal vesicle trafficking-associated protein 2, Neuron-specific protein family member 2.
What is the protein family that this protein belongs to?
Belongs to the NSG family.
What are the subcellular locations of this protein?
Membrane; Single- pass type II membrane protein. Golgi apparatus, trans-Golgi network membrane. Cell projection, dendrite. Endosome membrane. Early endosome membrane. Late endosome membrane. Lysosome lumen. Cytoplasmic vesicle membrane. Golgi apparatus, Golgi stack membrane. Endosome, multivesicular body membrane. Note=Endocytosed from the cell surface, thus entered into early endosomes, trafficks to late endosomes and degradates in lysosomes (PubMed:28874679). Mainly Golgi stack, but also found in small vacuolar organelles and multivesicular bodies. Found in both stationary and motile endosomes (By similarity).
Protein: SECF_ACIFV
Sequence: MKKFSIVKHARIFFSITAVVLIVGIVSMFARGFNLGIDFTGGSILDIKFDQPVTVAQVRTVLSDHQLGSSVIQLGSSDQQVESSQSVLIRTGLISDSQRVDVMNDLSNRLGHNEVLRVENVGATVGGDLVKSAVGAVVLSWVLMIIYITIRFELRFALAAIVALIIDVMVTLTWFSVLHLEIDSSFVAALLTVVGYSVNGTIVVFDRIRENLHTHRRNESMGDLVDASIWQTMTRSVYTTLTTLFAVVAIFLFGGETIHNFSFAMLVGFCSGFYTSTFLAGSMWLFFRKKLKR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecF.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecF subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CHLL_CHLAT
Sequence: MKIAVYGKGGIGKSTTSCNISIALARRGKKVLQIGCDPKHDSTFTLTGFLIPTIIDTLQSKDYHYEDVWPEDVIYKGYGGVDCVEAGGPPAGAGCGGYVVGETVKLLKELNAFYEYDVILFDVLGDVVCGGFAAPLNYADYCIIITDNGFDALFAANRIAASVREKARTHPLRLAGLVGNRTSKRDLIDKYVEACPMPVLEVLPLIEDIRISRVKGKTLFEMAESEPSLDYVCEFYLNIADQLLARPEGVVPKEVPDRELFSLLSDFYLNPANNASSIEQPTDSIVQSEQEPFLII
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CYSI_NITHX
Sequence: MNVKTEPDRSRDVSQPLDKLGPDETLKANSDYLRGTIKQSLADEITAAVTANDAKLMKFFGIYQQDDRDIRDERRRQKLEAAFSFMVRVRLPGGVCSPSQWLKLDALGRAYGGDTLRLTTRQTFQLHRIMKHNMRAVIQGLRDVLLDTRAACGDDTRGVMCTVNPDLSKLHAEVYALAKQASDHAVHRTGAYQEIWYEAERQDTDGPEEPFYGRTYMPRKFKIGFAIPPSNDIDVYGQDLGFIAIARRGKLKGFNVAIGGGLGRTDQSPKTYPRLATVIGYIDADKLFPTIDAVMSVQRDYGDRLDRLHARFKYTIDEKGLDWIKAEAERRLGFALEPAQPYTFTSNGDPLGWVKGEDGREHCTLFIQNGRVINTPDHPMMDGLRAIAQVHKGMFRITPNQNLIISDIAPEDRPAIAALMKQYGLDQFETRSGLRLNSMACVALPTCGLAMAESERYLPDLVTKIEAILNVHGLKDDPITIRMTGCPNGCSRPYIAEIGLTGRAPGKYNLYLGGGFHGERLNKMYLENVGEGAILEALDKTLGHYARDRKPGEHFGDFAIRAGYVVEVKEGRFFND
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: ATPD_FUSBL
Sequence: MAEAASISQGIAERYATALFELSKETGALKTLETDIDALKDVLAGSPDLGAMIASPVISRGDQAKAVAAIAGKMGLSPLMTNTLALMSEKRRLFALPQVLSALAGLIAEEKGEVTAEVTAATKLSAAQAKKLAETLKAKVGKTVKLNTTVDESLIGGLIVKLGSTMIDTSVKSKLASLQNAMKEVG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: OSMO_CALPC
Sequence: ATFTIRNNCPYTIWAAAVPGGGRRLNSGGTWTINVAPGTA
What is the function of this protein?
Has antifungal activity.  Inhibits spore germination and mycelia growth in F. solani (IC(50)=67. 0 ug/ml), C. gloeosporioides (IC(50)=32. 1 ug/ml) and a Neurospora isolate (IC(50)=57. 5 ug/ml).
What are the official names of this protein?
Osmotin, CpOsm.
What is the protein family that this protein belongs to?
Belongs to the thaumatin family.
Protein: PFF1_CANAW
Sequence: MSEEEVHDTSSEASEVFTNQPNAFVRGVRSIFGYRKTSLTLFVILTIVVTAGLSFYDNSLELTIELPTSQLEKEILESSWLDLQNIARYPHTYGSRANDQVHDYLEEIIQDMEYDNDGEKIMFESGKGVVSYYESNNLLVRVNGSDGTLPALLLSAHYDSVPSSFGVTDDGMGVASLLGVLRFVAHNQPRRTIIFNFNNNEEFGLFGAHAFVKHPWFKQVGYFLNLEGTGAGGKAVLFRGTDYGIVKNFGGVRYPYATSIFQQGFNNHVIHSETDYKVYKEAGLRGLDLAFYKPRDKYHTGEDNIRNVSPKSLWHMMSNAIDFVQMGVVDDSEEPAVYTTFLGYFFATPISALARVNLVLLVLFPVVSTPLLFVIVKYKKWKLRVTNFLGVPLAMGLAVAVGQVGNPMLVSSHPMMVVATTTSIVVLVYYVVLNGVDWVNTSSDQKLVTMIEVSFVYWVVLVYVTWSGGDHTGEFGVTVLFFVQASTSLLGLIGWTFTRVRGGDEPLLSGEEERYGTEDERDTEKPLVEHNYDWSLQYLLIVPVSSLVVYNSGWLVLEGVNKTVQESLASEHLIYWIVVVFSQFLVLPVVPFITKFNRYIVLGLSVVAVVGVLMSMAVHPFNQGSPMKLRFIERVGQNDMVEVYGRQGFVEDVLSDLPSVKQTQAKLECEALPDGLEVCKYKSGLTPGNLTVEVTTEPRAESYGLISGAITIAAPENRMCTVHFPPDRVKAVVVGKFGNNFKAIPDGFSREKGNYIYKDRNGISQLELYKLDWNKDYHVGFEWLPDIDDEGGMRVEVECFWGDMVPAYQEVVHYSPNWVTWANKERGLVGVVKHVDV
What is the function of this protein?
May be involved in vacuolar sorting and osmoregulation.
What are the official names of this protein?
Vacuolar membrane protease, FXNA-related family protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: ZNTB_KLEP3
Sequence: MDAIKGSELQIPDAIFAWVLDGQGGVKPLTDNDIIDKDKPCWLHLNYTHSDSADWLAATPLLPNNVRDALAGESTRPRVTRIGDGALITLRCINGSTDERPDQLVAMRLYMDERLIVSTRQRKVLALDDVLGDLKEGNGPTDGGSWLVEVCDALTDHASEFIEQLHDRIIDLEDDLLDQQVPPRGFLALLRKQLIVMRRYMAPQRDVYARLASERLPWMSDDQRRRMQDIAERLGRGLDEIDSCIARTAIMSDEIAQIMQESLARRTYTMSLMAMVFLPSTFLTGLFGVNLGGIPGNSWHLGFSLFCLMLVVVIGGVAWWLHRSKWL
What is the function of this protein?
Zinc transporter.  Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake.
What are the official names of this protein?
Zinc transport protein ZntB.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BIOB_ECOK1
Sequence: MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAWKNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVREAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMTPDTDEYYNAAAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: RK23_STAPU
Sequence: MIDYIKSPVLKFKLIRLLEKNQYTFDVDPKATKTDVKYWVENFFGVKVIGMNSHRPPRKMKRMGPTIGYPVRYKRMIVTLRAGDSIPLF
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RSPO2_HUMAN
Sequence: MQFRLFSFALIILNCMDYSHCQGNRWRRSKRASYVSNPICKGCLSCSKDNGCSRCQQKLFFFLRREGMRQYGECLHSCPSGYYGHRAPDMNRCARCRIENCDSCFSKDFCTKCKVGFYLHRGRCFDECPDGFAPLEETMECVEGCEVGHWSEWGTCSRNNRTCGFKWGLETRTRQIVKKPVKDTILCPTIAESRRCKMTMRHCPGGKRTPKAKEKRNKKKKRKLIERAQEQHSVFLATDRANQ
What is the function of this protein?
Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors.  Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes.  Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway (PubMed:21909076, PubMed:21727895, PubMed:22615920).  During embryonic development, plays a crucial role in limb specification, amplifying the Wnt signaling pathway independently of LGR4-6 receptors, possibly by acting as a direct antagonistic ligand to RNF43 and ZNRF3, hence governing the number of limbs an embryo should form (PubMed:29769720).
What are the official names of this protein?
R-spondin-2, Roof plate-specific spondin-2, hRspo2.
What is the protein family that this protein belongs to?
Belongs to the R-spondin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GGT6_MOUSE
Sequence: MDATTGPVHYHKLQLWEPGVESEEEEEEEEEEIAEPLVLSLRRLQNTPRNEVGGLPGAWARLLAGLLLLAVSSSLALRQLHSRDSPRGNLGSVAPPASRHSHRPGVYHHSAIISPAATCSQLGQELLVAGGNVVDAGVGAALCLAVVHPHATGLGATFWGLFYNSSSGNSTALTAGPTQLLAPGLGLPTGLPALHLLHAHFGRLPWPHLLTKPAMLAEKGFEVDAPLANALAIQGTKGLCPLFCHTNGTPLGLGARATNPNLAAVLRSAALASSPDLAGKALLNPLVRDLGLELPSAQPVPSLEPALQLLLPRGVLFTTPGPSAGPELVELLESTLHSRTPSSAPCPPFLQTAETPVSSALATVDSNGSMLLLISSINSSFGSGHLSPSTGVLLSNLEASPAPSAWACPLILRDNLDDTEADMLGMVASGISRGAKAMTCTLLNHLATPQIPQQPQHQRPTESPGICGQGALLQAVVHAEHAHVSSVPSGCCPFQGY
What is the function of this protein?
Hydrolyzes and transfers gamma-glutamyl moieties from glutathione and other gamma-glutamyl compounds to acceptors.
What are the official names of this protein?
Glutathione hydrolase 6, Gamma-glutamyltransferase 6, GGT 6, Gamma-glutamyltranspeptidase 6.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyltransferase family.
What are the subcellular locations of this protein?
Membrane; Single- pass type II membrane protein.