PharMolix/UniProtQA huggingface dataset:
Protein: ATPL_SYNE7
Sequence: MDSLTSAASVLAAALAVGLAAIGPGIGQGSAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALVLLFANPFA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: PRR5L_HUMAN
Sequence: MTRGFAPILPVEFHKMGSFRRPRPRFMSSPVLSDLPRFQAARQALQLSSSSAWNSVQTAVINVFKGGGLQSNELYALNENIRRLLKSELGSFITDYFQNQLLAKGLFFVEEKIKLCEGENRIEVLAEVWDHFFTETLPTLQAIFYPVQGQELTIRQISLLGFRDLVLLKVKLGDLLLLAQSKLPSSIVQMLLILQSVHEPTGPSESYLQLEELVKQVVSPFLGISGDRSFSGPTYTLARRHSRVRPKVTVLNYASPITAVSRPLNEMVLTPLTEQEGEAYLEKCGSVRRHTVANAHSDIQLLAMATMMHSGLGEEASSENKCLLLPPSFPPPHRQCSSEPNITDNPDGLEEGARGSQEGSELNCASLS
What is the function of this protein?
Associates with the mTORC2 complex that regulates cellular processes including survival and organization of the cytoskeleton (PubMed:17461779).  Regulates the activity of the mTORC2 complex in a substrate-specific manner preventing for instance the specific phosphorylation of PKCs and thereby controlling cell migration (PubMed:22609986).  Plays a role in the stimulation of ZFP36-mediated mRNA decay of several ZFP36-associated mRNAs, such as TNF-alpha and GM-CSF, in response to stress (PubMed:21964062).  Required for ZFP36 localization to cytoplasmic stress granule (SG) and P-body (PB) in response to stress (PubMed:21964062).
What are the official names of this protein?
Proline-rich protein 5-like, Protein observed with Rictor-2, Protor-2.
What is the protein family that this protein belongs to?
Belongs to the PROTOR family.
Protein: ISPF_ECO24
Sequence: MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: THII_ACHLI
Sequence: MEKAILIRFGDLVLKGKNKPKFIGQIKKNIRSKLKNVNVEYTFQHDRIYVHFNEVDSDEVIKQLGYVSGIHSFSYIYKTTKDIESIAQLAKEVIQKEVKLPTTFKIETKRTDKNYPLKSLEISQKVASLVLPSFDGLKVEVRNPETVLDIELRSEGTYIYVGKIPALGGFPIGLGGKGLVMLSGGIDSPVAAHLMMKQGIDVELFHFESTPLTPLESVQKVIEIAKKLAYYTPYNKIKLHLVPFTKIHEAILSYVADPYIITIMRRMFYRLGEIYANQHGLDTLINGESVGQVASQTLSSIKVIENVTSIPILRPVITYDKNDIINISKKIDTYDISILPFNDCCSIYVPRNPVTKPTIDQALKEESRFEFKELLEDALKNVQTMIITPTTDFEIALHGFDVKDALSSYTQE
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_AMOA5
Sequence: MVEEKTIRLSQVARKLNVATTTIAAYLLEKGFRVENKPNTKITLEQYKILAEEFADSAMDKEEAAELVIGQSYEKEPKVIAKQQEPIKHVHPKEKQVEIEKISLPVIDAPTIIEHKIIEHKTEEPPILQPELPTEEKEELEVIESPQAPQEELKPELETEVQEQDKEIQQELDDTAKVEQAPITKGPEKIDFSKQGEFKGVTVLGKIELAEKKEPKKFQQVASSDIDKKNKKRPRKRVASETGLPSSGKREEEANRYKPKGKVTNKTPEAPKTAVSEKQIQDQIKSTLAKLGGGKNVASRAKYRREKRSLLAEEQAEERLQAAKDAKKLQVTEFIAASDLASLMGVSINQLLSTCMNLGMLVSINQRLDAEAITIIADEFGYQVAFTDVKTQELEEEEEANPEDLVERAPIVTIMGHVDHGKTSLLDYIRNTQITKTEAGGITQHIGAYEVVTESGKHIAFLDTPGHEAFTAMRARGAKLTDIAIIVIAADDGVRPQTKEAINHAKLAGVPIIIAINKMDKPQANPERVKEELAHLNILVEDWGGKYQSQGVSAISGEGVKELLEKILFEAELLELKANSHKKARGTVIEASLDQGRGYLATIMVQDGNLRIGDVVLAGAYYGKIKAMFDYQGKPVKQAGPSTPMQILGLNGAPQAGDLFRAMNTEKEARDIATQRQQILREQGFRTKTHITLDEIGRRLAIGNFKELNIILKGDVDGSVEALSDSLLKLSTEEIKVTILHKGVGAIVESDILLAAASDAIIIGFQVRPTPPVRKLAEKEGIEIRLYSIIYDAINDIKDAMEGMLAPTIEEIITGSASVREIFKITGTGTVAGCYVTEGYIKKNNSIRVIRDGIVIYTGSIKHLKHFKEEMQQVKTGFECGISITNFNDLKVNDVIEGFEQKEVERKL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM23_ASHGO
Sequence: MFRRIVAVPSSWSSLQLFSTSAVRSSNGLAAILEQVSAKKSAPREAKTPSKYADRKPQHSSPVRKKKVFVRWTTGSEKAREIANTVVSEVLSIRSDGRLRLILPEENRIQELSMQDVARQLDLEVHSLRFIKSETDAGGRPLPLVKRVSVREAFRVHAERMAAEREKELLRKGVSARRVGAKERRAPDSKQVRISWQISPTDFSNQKSKEIRGHLERGHTVLVLLANKDASGPAPQVSPRELQRRSSLLDELAAILEDINCSVVRSGDPASRVELKLVPKAPQEVDRHALKEQRRLQRAEKLKRRLERRGPASAQE
What are the official names of this protein?
Altered inheritance of mitochondria protein 23, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM23 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RECR_BACLD
Sequence: MQYPEPISKLIDSFMKLPGIGPKTAVRLAFFVLSMKEDVVLDFAKALVNAKRNLTYCSVCGHITDQDPCYICEDTRRDKSVICVVQDPKDVIAMEKMKEYNGLYHVLHGAISPMDGIGPEDIKIPELLKRLQDDQVTEVILATNPNIEGEATAMYISRLLKPSGIKLSRIAHGLPVGGDLEYADEVTLSKALEGRREM
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: MLTC_ACTP2
Sequence: MKKYTKYLPLLLIIPFLAACGSSSPKKSKRTKTRVDYNTKDTNGLDILTGQFSHNIDDIWGSNELLVASKKDYVKYTDKFYTRSHISFEDGQITIETLGDQNHLRNSIIHTLLMGSDPKGIDLFASGDAPISSNPFLAGQVNDQFGRDINNIAIANDFATYLIQNKLQTRRLQNGRTVTYVAIKMVAGHIEVRARQYLPLVRKMAKRYGIEPSLILGIMEVESAFNPYAVSYANAIGLMQVVPRTAGRDIFARKGFDGQPDRAYLYNPSQNIDSGTLYLAILRDEYLEGITNPTAKRYAMISAYNSGAGAVLKVFDYDKYDAIDRINELSPDAVYRILTTAHPSSQARNYLKKVSKAREKYLHIR
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase C, Murein lyase C.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RL2_PYRFU
Sequence: MGKSLIQQRRGKGSPTFKSPSHRFRGAVKYIPLNYTQEKTLRGVVEEIMHDPGRTAPVARVKFENGIEKLIIAPEGLLVGQEIYIGPDAPIAVGNTLPLAKIPEGTYVYNIEGIPGDGGKYVRAGGTYALVVSREPDKVIVQLPSGELKAFNPMCRATIGVVAGGGRLEKPLVKAGKAYYKYKARNKFWPTPRGVKMNAVNHPFGGKEHHPGKPTTTSRRAPPGRKVGHIAARRTGRRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2, Large ribosomal subunit protein uL2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: KAD2_DROGR
Sequence: MAPNAARPVERYESNNHGVNAILLGPPGSGKGTQAPLLKEKFCVCHLSTGDMLRAEIASGSKLGSDLKKVMDAGKLVSDDLVVDMIDSNLDKPECKNGFLLDGFPRTVVQAEKLDTLLDKRKTHLDAVIEFAIDDNLLVRRITGRLIHQASGRSYHEEFAPPKVPMKDDITGELLMRRSDDNAEALKKRLESYHKQTKPLVDYYGLRGLHFKVDAAKKASDVFSSIDSIFLRKAHANA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.  Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
What are the official names of this protein?
Adenylate kinase, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate kinase cytosolic and mitochondrial, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Mitochondrion intermembrane space. Note=Predominantly mitochondrial.
Protein: PSBA_CUSGR
Sequence: MTVVLDRRKSENLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFLIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASIAEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAIAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTESESANKGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVIGIWFTALGISTMAFNLNGFNFNQSVVDSKGHVINTWADIINRANLGMEVMHERNAHNFPLDLATFEVSATNA
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid membrane; Multi-pass membrane protein.
Protein: TRPC_RHOJR
Sequence: MTVLDSILDGVRADVAAREAVLDFAAVKAAAAAAPPALDAAAALLEPGIGVIAEVKRASPSKGALADITDPAELAAAYQAGGARVISVLTEERRFQGSLADLDAVRRAVSIPILRKDFIVGPYQIHEARAHGADVVLLIVAALEQDALASLIDRTESLGMTALVEVHTEEEANRALEAGAKVIGVNARNLKTLEVDKNTFGEIAPGLPTEIIKIAESGVRGTADLLAYAGAGADAVLVGEGLVTSGDPRKAVADLVNAGAHPSCPKPSR
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: RLMH_MYXXD
Sequence: MKVRLLSIGKDRSGLYEPAVQEYAKRLGHYTRFELVEMAEASGKRLKPGDAKAAEAEAILSKRKPQDWLVALDERGSLLDSVELSRYVGKAQTGAKDLLFIIGGDEGLDARVRDAANLTLSLSKMTLPHRLARVVLIEQLYRAFTILKGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F110B_PONAB
Sequence: MPTETLQTGSMVKPVSPAGTFTSAVPLRILNKGPDYFRRQAEPNPKRLSAVERLEADKAKYVKSQEVINAKQEPVKPAVLAKPPVCPAAKRALGSPTLKVFGNHAKTESGVQRENLKLEILKNIINSSEGSSSGSGHKHSSRNWPPHRSEATDLHRHSFAESLKVYPTQGRSSPQEGGSHVGRRLLEQSAESFLHVSHSSSDIRKVTSVKPLKAIPCSSSAPPLPPKPKIAAIASMKSPEADPVEPACGVSRRPSLQRSKSDLSDRYFRVDADVERFFNYCGLDPEELENLGMENFARANSDIISLNFRSASMISSDCEQSQDSNSDLRNDDSANDRVPYGISAIERNARIIKWLYSIKQARESQKVSHV
What are the official names of this protein?
Protein FAM110B.
What is the protein family that this protein belongs to?
Belongs to the FAM110 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: AAS_YERP3
Sequence: MAYRLLRALFRGLFRVTIDGVTDQFKHEKLIITPNHVSFLDGALLALFLPIKPVFAVYTSITDTWYMRWLKPYVDFVALDPTNPMAIKHLVRMVEQGRPVVIFPEGRITVTGSLMKIYDGAAFVAAKSGAAVVPIRLDGPEFTHFGRLQGVLKTRWFPKISIHVLPATTIPMPQAPRSRERRVLAGEHLHTIMMAARMATVPRETLFEALLSAQTRYGRFKPCIEDVSFKEDSYQTLLKKTLGVSRILQRFTVPGEHVGMLLPNATITAAAIFGASLRGRIPALLNYTSGAKGLQSAIIAASLKTIVTSRQFLEKGKLTHLPEQVNEVNWVYLEDLKDTVTLTDKLWILFHLCFPRRAMLPQQADDSALILFTSGSEGNPKGVVHSHASLLANVEQIRTIADFTPRDRFMSSLPLFHAFGLTVGLFTPLMTGSRVFLYPSPLHYRVVPELVYDRNCTVLFGTSTFLGNYARFAHPYDFARVRYVVAGAEKLAESTKQIWQDKFGIRILEGYGVTECAPVVAINVPMAAKVNTVGRILPGMEARLINVPGIAQGGRLQLRGPNIMRGYLRVENPGVLEQPSAENAQGELDANWYDTGDIVTLDEQGFCAIRGRVKRFAKLAGEMVSLESVEQLAISLSPEGQHAAAAKTDSAKGEALVLFTTDSEITRERLIKAARENGVPELAVPRDIRVVKALPLLGSGKPDFVTLGKMAQDPEMSV
What is the function of this protein?
Plays a role in lysophospholipid acylation.  Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium.  Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.
What are the official names of this protein?
Bifunctional protein Aas.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPRTL_BACSU
Sequence: MDNKELQKLTEDISETYFKKPFRHQALFNDRLKTTGGRYLLTSHNIELNRKYLIEHGREELIGIIKHELCHYHLHLEGKGYKHRDRDFRMLLQQVNAPRFCTPLKKKAENKKTYMYICTTCGQQYIKKRAMNPDRYRCGKCRGKIKRIFS
What are the official names of this protein?
Protein SprT-like.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADE_PARPJ
Sequence: MTTTTVTPTPLAEKTALAPKAELHIHIEGSLEPELIFALAERNGVKLAYDSIDALRAAYAFTDLQSFLDIYYAGASVLLHEQDFYDMTMAYVERCLADNVIHSEIFFDPQTHTERGVPIATVVAGIERALADAEKRGMTSKLILCFLRHLSEEDALATFEEALPLFEQYKHRLIGVGLDSSERGHPPSKFERVFAKARALGLKLVAHAGEEGPPSYIYEALDLLKVDRVDHGVRSIEDPALVTRLADSRVALTVCPLSNLKLCVFDDLTKHTLKDLLDRGVAVTVNSDDPAYFGGYVNANYFATIDALKLNDAEVYTIIRNSFEASFVTPEQRSELIAKLDAHWHPSGPH
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
Protein: Y392_PSEAE
Sequence: MIGLNTAAIYILQTLGSLYLLIVLLRFILQLVRADFYNPLSQFIVRATKPLLNPLRRIIPGFGGIDLASLVLAILIQLVLMILILMLMGYGVGGFIMQLLIWSIIAVTSLFLKVFFFALIISVILSWVAPGSYNPGAQLVNQICEPLLMPFRKLLPNLGGLDLSPIFAFLALKLIDMLVINNLAAMTGMPQQLSIFL
What are the official names of this protein?
Uncharacterized protein PA0392.
What is the protein family that this protein belongs to?
Belongs to the YggT family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSMC_PSEPF
Sequence: MDPRSEVLLRQAELFQGSVLLAGLPADDLLGRLPDAFGWCWHAGDQAALDARFEGRSHFGVNVPERSFDTAVVFLPKAKDLTDYILNAVASRLAGREVYLVGEKRSGIEGASKQLNPFGKPRKLDSARHCQLWQVTVANAPEAKPLESLAQTYELPLAEGPLKVISLPGVFSHGRLDRGSALLLEHLDKLPSGHLLDFGCGAGVLGAAVKRRYPHNQVTLLDVDAFAAASSRLTLAANGLEAEVLTGDGIDAAPMGLNAILSNPPFHVGVHTDYFATENLLRKAAKHLKNGGELRLVANSFLKYQPLIEEHLGVCAIKAEGNGFRIYRAKRG
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPTD_PARXL
Sequence: MPPRQLSQTTPSCAVVPRKRRLVAALIAVPGLMPALAHAQLVGEAAQPQPIDAPWGMQLAPQLEERPLQPGQKPATFVLGDTTSGTTDQDMAAKGSAEVRRNTVVIKADALHYDQDTDMADAYGSVHVVNNGNSFVGPEAHMRVDSSEGFMTAPKYHFNVTGGSGSAERVDLLDNERSVFTKGTYTACACADDPAWYIKGSEFDFDTGADEGVAHNGVLFFQGFPVFASPWLSFPLSGERRSGVLPPTFSLSSSNGFELSVPYYFNIAPNRDLTLTPRLISKRGVQLQSTFRYLSPTYSGSITGEFLPDDHLTKTNRYALYIQHNQNFGNGFGGYIYYNKVSDNTYPEDLSSSVNQFMNGTQLLYQQEAGLTYNNGPWSVLAREQHWQTLTPSVAPYGREPQLNVKYAKYNVGGFDYGAEADYSNFRITTADMTQGQRVMFNPYLSYSVVGPGYFVTPKVQWHFASYNLNHLSDADVAAGTPKNFTESIPTLTFDTGLVFDRSVRIFGQDYIQTLEPRLYYVYTPYRNQQSAPLFDTADSDFGLAEIFTPNTFVGNDRIADANRLTAALTTRFIDAATGDERARFVIAQQYYFQDQRVTLQSTQTSAQATHSDLIAGASLKLGAGFASETAFQYNADNNQLVKTSVGFGFSPATGKVINVAYRYTRANTTLDNTPINQVLISGQWPLAHRVYGVGRFNYDLGGHRIVDGLVGLQYDADCWTLGAGIQRYANGLNTSGQNQSSTRFLAQLTFKGLSSVDNGLMTAFRSSVAGYTPLPPPPPPESRFTNYE
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RL14_ACHLI
Sequence: MLQQESRLLVADNSGAREVLVIRVLGGTRRRYANIGDIVTVTVKKASPTGTVKKGDVVKAVVVRTKHGIRRADGSTIKFDDNAAVIIKDDMNPRGTRIFGPVARELREKNFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: UBA4_YEAS7
Sequence: MNDYHLEDTTSELEALRLENAQLREQLAKREDSSRDYPLSLEEYQRYGRQMIVEETGGVAGQVKLKNTRVLVVGAGGLGCPALPYLAGAGVGQIGIVDNDVVETSNLHRQVLHDSSRVGMLKCESARQYITKLNPHINVVTYPVRLNSSNAFDIFKGYNYILDCTDSPLTRYLVSDVAVNLGITVVSASGLGTEGQLTILNFNNIGPCYRCFYPTPPPPNAVTSCQEGGVIGPCIGLVGTMMAVETLKLILGIYTNENFSPFLMLYSGFPQQSLRTFKMRGRQEKCLCCGKNRTITKEAIEKGEINYELFCGARNYNVCEPDERISVDAFQRIYKDDEFLAKHIFLDVRPSHHYEISHFPEAVNIPIKNLRDMNGDLKKLQEKLPSVEKDSNIVILCRYGNDSQLATRLLKDKFGFSNVRDVRGGYFKYIDDIDQTIPKY
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1.  Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus.  The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1.  Subsequently, a transient disulfide bond is formed.  Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  May also be involved in protein urmylation.
What are the official names of this protein?
Adenylyltransferase and sulfurtransferase UBA4, Needs CLA4 to survive protein 3, Ubiquitin-like protein activator 4.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_HAES1
Sequence: MTTSATLFSRAQQVIPGGVNSPVRAFKGVGGTPVFIEKANGAYIFDTEGKQYIDYVGSWGPMILGHNHPSILSAVLKTAENGLSFGTPTPLEIELAELICQLVPSIEMVRMVNSGTEATMSAIRLARGYTKRDKILKFEGCYHGHSDSLLVKAGSGSLTLGQPSSPGVPEDFAKHTITCEYNNLQSVKNAFEQYPDQIACVIVEPVAGNMNCILPKQDFLQGLRQLCNEYGSLFIIDEVMTGFRVALGGAQSYYEVTPDLTTLGKVIGGGMPVGAFGGKKEIMQYIAPTGPVYQAGTLSGNPIAMSAGIACLNELKKEGNEQRLAMLTKKLALGLKNLANQHNIPLVVNYVGGMFGIFFTTQNEVTSYQQAIQCDVEKFNLFFHKMLEQGVYLAPSAFEAGFMSLAHTDADIDRTLQAADIAFASLCSSSFS
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_ACIF2
Sequence: MARENRDTQPNDGMQEKLIHINRVSKVVKGGRQFGFAALMVVGDGDGKVGFGRGKAKEVPAGIQKATDQARRWMTSIPLMRGGTIPYPVEGRHGAARVMLRPAPEGSGVIAGGAMRAVCEAVGLRNVVAKSLGSNNPINVVRATFDAFDKLISPQAIAMKRGKSLKEIRGQGGHDE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: ARP5_AEDAE
Sequence: MSLFDIEDIKVKPDIVCTYPDPTVPPDAAIVIDNGSYHCRAGWAGKDVPSLVFKNVLAKPRKDRSKKDTSEVVVPTVQIGNDITNIEAVRFQLRTQFDRNVVTHLHVQEQIFDYLFGRLGINADGCVPHPVLLTECVANPNYSRMLMSELMFECYGIPGIVYAVDGLLSYRMNGGQDSGLIVSCGYQATHVIPVLNGRMVEDKVRRINLGGFNMINFMFRLLQLKYPVHVNAITLSRAETMIHNYCSFAYDYTESLRNWALLEFYEQNVIKIQLPYNQNVSAPTLTAEQRLEKRKELSRRLAEINLRKREEKLAEDKVLLTRMLAAEDTLDDEDNVGFTLHEFSVKNVDEYRKMIVTLRERIAKTTQKMNSQQTNNQPEEKPLQLLQPPPNMTIEEWVIETRRKRDEILDKKQIRKQRKQDLAKRRTAAAQERMRIISHLAKKEKGVDDFGMRDEDWDVYKSISREGDSDSDAENEKLIECEEILKQHDSTFVEPVVAPGNIAEFHQLHIGVERIRVPEILFQPSMIGVQEAGLTGTIDYVLKLFPKEDQVKLVGNVMLTGGCANIRGFKERLSRELQAILPFQSVYNLMVAGSPSLDAWRGASQFANSQEFKQSLITRQLYDECGGEYFKEHTASNFYYPTPSQVSSALNDTFN
What is the function of this protein?
Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
What are the official names of this protein?
Actin-related protein 5.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP5 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: BFR2_ASHGO
Sequence: MGKTLADQITELANKSKVPDFDIEDEQVFEHDSNASGSEASDEDEALQAAHYVQVGRSKLRNKHNVLVEDSKYSGSKGSREALFNSSGEEDGSESDRRGSDSDGGSDSDSDAPEATLSSEQSADESARSDSDSGDSDSDSGSDAGEENSAVAEDADAKRERLSQLVRLETQQAMGKLNAAVQNDALKGYAIMEQSRFFEGAIDVRIKLQKAIAAANQLPLTKQSWESRLDAQDAELLESTCKLLHKVAGKCAELRTTFQNKERINQTEIDYQPSKKRSIDALAEQCHDLDSQLRDYRGAVLHMWSSKVAATSGKTALSSSKFKAINQPANVQVDNQLADMPRLVKRTQLNRRGVVPLGFEEDYKQKRLPLLDSNSAQDGGQEEDADVPANYDPRKKDNNAIDASENPYIFDDEDFYRVLLNDLVDKKILNAQQGSNVQVAIKARSQNKLKKNVDTKASKGRKLNYSVQEPIANYEAPINGGFKWSDEQIDEFFAGLLGQRVNFDERETSEAKDNEEEAIEHDDLRIFG
What are the official names of this protein?
Protein BFR2.
What is the protein family that this protein belongs to?
Belongs to the AATF family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: HLDD_EDWI9
Sequence: MIIVTGGAGMIGSNIVKALNDKGYTDILVVDNLKDGTKFVNLVDLDITDYMDKEDFIAGIVAGDDFGDIDAVFHEGACSSTTEWDGKYVMDNNYQYSKELLHFCLERQIPFLYASSAATYGMTDKFVEDRHYEGPLNVYGYSKFLFDQYVRRILPHAKSQICGFRYFNVYGPREGHKGGMASVAFHLNTQINNGEQPKLFEGSENFRRDFIYVGDVADVNLWFWENGVSGIFNCGTGNAESFQAVADAVVAYHQKGSVTYIPFPDKLKGRYQAFTQADTTQLRAAGYSRPFKTVAQGVREYMEWLNRKP
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.