PharMolix/UniProtQA huggingface dataset:
Protein: SRY_PRZAL
Sequence: MFRVLNDDVYSPAEIQQQNPLAFGKASSLFTDNRSANDQCETGENVRESGQDHVKRPMNAFIVWSRERRRKVALENPKMQNSEISKQLGYEWKRLTDAEKRPFFEEAQRLLAVHRDKYPGYKYRPRRKRKRQQKLLPADSSKLCKQMHIETLQPFTYRDGCANTTGSRMESQLSLSQSVTITNSFFQNEHHSSWTNLGHNRVTLATQISADFPFYQSLQPELSCAYFQY
What is the function of this protein?
Transcriptional regulator that controls a genetic switch in male development.  It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.  Involved in different aspects of gene regulation including promoter activation or repression.  Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.  SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.  Also involved in pre-mRNA splicing (By similarity).  In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
What are the official names of this protein?
Sex-determining region Y protein, Testis-determining factor.
What is the protein family that this protein belongs to?
Belongs to the SRY family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Nucleus.
Protein: NIKR_SALSV
Sequence: MQRVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRGALAQEATQEHGTQGFAVLSYVYEHEKRDLASRIVSTQHHHHDLSVATLHVHINHDDCLEIAVLKGDMGDVQHFADDVIAQRGVRHGHLQCLPKED
What is the function of this protein?
Transcriptional repressor of the nikABCDE operon.  Is active in the presence of excessive concentrations of intracellular nickel.
What are the official names of this protein?
Nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: RS4_SALTY
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQAPGQHGARKPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGENLLALLEGRLDNVVYRMGFGATRAEARQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALELAEQREKPTWLEVDAGKMEGTYKRKPERSDLSADINEHLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: NLGNX_MACMU
Sequence: FQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPEDTTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRRPSPQRNTTNDIAHIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPLMTPNTITMIPNTLTGMQPLHTFNTFSGGQNSTNLPHGHSTTRV
What is the function of this protein?
Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members.
What are the official names of this protein?
Neuroligin-4, X-linked.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Postsynaptic density membrane.
Protein: LEUC_RHIME
Sequence: MSAPRTLYDKIWDDHLVDSQDDGTCLLYIDRHLVHEVTSPQAFEGLRMAGRKVRAPEKTLAVVDHNVPTSPDRHLGIKNEESRIQVEALARNAADFGVEYYSENDKRQGIVHIVGPEQGFTLPGMTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLIQKKAKNMLVRVDGQLPPGVTAKDIILAIIGEIGTAGGTGHVIEFAGEAIRSLSMEGRMTVCNMTIEGGARAGLIAPDETTFEYIKDKPRAPKGEAWDRAVEYWKTLHTDEGAHYDRVVVLDAANLPPIVSWGSSPEDVVSVQGVVPNPDDIQDETKRTSKWRALDYMGLKPGTKITDIAIDRVFIGSCTNGRIEDLRAVAEVVEGRKVAPTVSAMIVPGSGLVKEQAEAEGLDKIFKEAGFDWREPGCSMCLAMNDDRLKPGERCASTSNRNFEGRQGFKGRTHLLSPAMAAAAAVAGHFVDIREWK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: PUR5_LACH4
Sequence: MNRYKDAGVDVEAGYDLVKRIKKDIAATSRPETSGTIGSFGGMFDLEKLGYQHPVLVSGTDGVGTKLMIAQEMGINDTIGIDCVAMCVNDVLAQGAEPLFFLDYIATGHNDPAKLAQVVHGVAEGCRQSGSALIGGETAEMPDMYPKNEYDLAGFSTGIANKEDILTQDLAKEGDILIGLPSSGVHSNGFSLIRQVLFKDHHLKVTDRPEALEGKSIGEILLTPTKIYVQAVLSLVKRHLLHGIAHITGGGLIENLPRTYNDDLQAEVNLGAWPVQAIFRYLQNKGQLKEQDCLNTFNMGIGLVLLVPKANVLQVKEQLKQKNEQYYEIGKLRKRPIGEKKIVFNGSFK
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_ANASK
Sequence: MAIERTLSIIKPDGVEKGIIGKIIGRFEEKGLKPVAIRLTQLSKAEAEGFYAVHKARPFFGDLVKFMTSGPVVLMVLEGENAVARNREIMGATDPKKADAGTIRKDFATDIEKNTVHGSDSAENAKIEVSYFFPEVQVHAYEWKKLA
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_MYCGE
Sequence: MKIILKQDVAKLGKRFDVVEVKDGFAIHFLFPKKLAAPLTKKAIANRDLFLKQQQEQYQKNRALAEKLKLVIEQTPLTFQLKQHDGKPYGSIITKQIINLAKQQRLDLQRFMFKDNVRLQFGEHKLILHLFEEITATLTVIVNPENGTTN
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: EFTS_MESM1
Sequence: MVDAEKIKKLREMTDSGFLDCKKALEATKNDLNAAVKWLQENGKAKAAKKADRITAEGLVAAFSNDKYGVIIEINSETDFVAKNQKFKDLVNKIGQELLKHDFYKYKNIIEEVKIGNETLAELVASASATIGEKLTFRRAEQVKKFNSKQVIGVYNHFDGQKAAVLIIENGTEDMAKQLSMHITAMNPLFLDEKEVPEKEIKKLRSEFEKDEQIQLKPEKIRPKIIEGMINKKLSETTFTLQEFVVEPGQSIKQYMNSKNSFPISKIRYEVGEGIEKQVVDFASEVANQMKNKA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
Protein: M1IP1_RAT
Sequence: MMQICDTYNQKHSLFNAMNRFIGAVNNMDQTVMVPSLLRDVPLSEPDLDNEVSVEVGGSGSCLEERTTPAPSPGSANGSFFAPSRDMYSHYVLLKSIRNDIEWGVLHQPSSPPAGSEEGTWKPKDILVGLSHLESTDAGEEDLEQQFHYHLRGLHTVLSKLTRKANILTNRYKQEIGFSNWGH
What is the function of this protein?
Plays a role in the regulation of lipogenesis in liver.  Up-regulates ACACA enzyme activity.  Required for efficient lipid biosynthesis, including triacylglycerol, diacylglycerol and phospholipid.  Involved in stabilization of microtubules (By similarity).
What are the official names of this protein?
Mid1-interacting protein 1, Gastrulation-specific G12-like protein, Mid1-interacting G12-like protein, Protein STRAIT11499 homolog, Spot 14-related protein, S14R, Spot 14-R.
What is the protein family that this protein belongs to?
Belongs to the SPOT14 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Note=Associated with microtubules.
Protein: CYB_ZENNE
Sequence: MASLRKTHPLLKIVNDALIDLPAPSNISAWWNFGSLLGLCLVTQILTGLFLAMHYTSDVATAFSSVAHICRDVNYGWLIRNIHANGASFFFICLYLHIGRGLYYGSYLYKETWNIGVVLFLLVMMTAFVGYVLPWGQMSFWGATVITNLLSAVPYVGDTLVQWIWGGFSVDNATLTRFFAFHFLFPFIIVALTVLHFFFLHETGSNNPTGINSDADKVPFHPYFSYKDLFGLVLLLLALSSLSFFSPNLLGDPDNFIPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLASILILMLVPILHTSKQRGLMFRPLTQLLFWILVADVMILTWIGGMPVEHPFIAVGQIASVLYFTLFLILIPTTGWLENKILEWN
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HIS7_CHRVO
Sequence: MRTATVTRNTLETQITVSLNLDGTGVGRFETGVPFLDHMMDQIARHGLIDLDVKAVGDLHIDAHHTVEDIGITLGQAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDLSGRPGLVYNVDYTRACIGQFDVDLFSEFFHGFVNHSMVTLHIDNLRGHNSHHQAETIFKAFGRALRMACEHDERMAGITPSTKGTLSV
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MBEA_ECOLX
Sequence: MIVKFHARGKGGGSGPVDYLLGRERNREGATVLQGNPEEVRELIDATPFAKKYTSGVLSFAEKELPPGGREKVMASFERVLMPGLEKNQYSILWVEHQDKGRLELNFVIPNMELQTGKRLQPYYDRADRPRIDAWQTLVNHHYGLHDPNAPENRRTLTLPDNLPETKQALAEGVTRGIDALYHAGEIKGRQDVIQALTEAGLEVVRVTRTSISIADPNGGKNIRLKGAFYEQSFADGRGVREKAERESRIYRENAEQRVQEARRICKRGCDIKRDENQRRYSPVHSLDRGIAGKTPGRGERGDDAAQEGRVKAGREYGHDVTGDSLSPVYREWRDALVSWREDTGEPGRNQEAGRDIAETEREDMGRGVCAGREQEIPCPSVREISGGDSLSGERVGTSEGVTQSDRAGNTFAERLRAAATGLYAAAERMGERLRGIAEDVFAYATGQRDAERAGHAVESAGAALERADRTLEPVIQRELEIREERLIQEREHVLSLERERQPEIQERTLDGPSLGW
What is the function of this protein?
Relaxase involved in plasmid ColE1 conjugative mobilization and is thus essential to promote the specific transfer of the plasmid during conjugation.  First catalyzes the specific cleavage of one of the DNA strands at oriT, forming a covalent 5'-phosphotyrosine intermediate.  The nic site corresponds to 5'-(1469)CTGG/CTTA(1462)-3' in the cleaved strand.  The cleaved strand is then transferred through the dedicated type IV secretion apparatus.  MbeA remains covalently linked at the 5' end of the strand, and once in the recipient cell, it probably catalyzes the rejoining of the two ends of the strand, re-forming the circular plasmid DNA.  Is functional in vitro without a requirement for the conjugative accessory proteins.
What are the official names of this protein?
DNA relaxase MbeA, DNA nickase, Mobilization protein MbeA.
What is the protein family that this protein belongs to?
To E.coli MbaA and MbkA.
Protein: DEF_LACDB
Sequence: MILMKDIVRDGDPVLRQVAQKLTFPLSDHYRKLADDMMEYLVNSQDPKIAAKHQLRAGVGLAAPQVGEGVSMAALLVPDDKGEIIFKEVYVNPEIISESVRKTCLSEGEGCLSVDKVIDGYVPRPNKVTVHYWTVDGEEKAIRLKGYPAIVSGHEIDHLNGHLFYDRINKENPFALDEDTIVIY
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: NRAM_I80AD
Sequence: MNPNQKIICISATGMTLSVVSLLVGIANLGLNIGLHYKVGYTPDVNTPNVNGTNSTTTTIINNNTQNNFTNITNIIQNKNEERTFLNLTKPLCEVNSWHILSKDNAIRIGEDANILVTREPYLSCDPQGCRMFALSQGTTLKGRHANGTIHDRSPFRALVSWEMGQAPSPYNAKIECIGWSSTSCHDGISRMSICMSGPNNNASAVVWYGGRPVTEIPSWAGNILRTQESECVCHKGICPVVMTDGPANNKAATKIIYFKEGKIQKIEELTGTAQHIEECSCYGAKEVIKCICRDNWKGANRPVITIDPDMMTHTSKYLCSKILTDTSRPNDPNNGNCDAPITGGGPDPGVKGFAFLDGENSWLGRTISKDSRSGYEVLKVPNAETNTQSGPITHQIIVNNQNWSGYSGAFIDYWANKECFNPCFYVELIRGRPKESSVLWTSNSIVALCGSRERLGSWSWHDGAEITYFK
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: TRI14_TRIAR
Sequence: MQPQVLLSSLLPLSDYISGWSWGSLLGNQPCPPLPAGDLVMRKYQMYPENFMWDKKRCVAYVSNLYNATLSIYDPYKSEVIDTISFPGLSHPGDSATPNPLHTSGLILRPDAATADLLEIVVDNGDCFFSNGNNVSGPDYLLTMDLRTKKVISQIRLNDISNGTYAGYADAELASDGNSYVVGTYVSNILRVTPQSEVSTFFVQEPLGPPREYGYTGLAHVGNVLLSNDNIAKQLVRFDIRDEKGTPVFIPQTPYHEFTTSNVMNLPEKYNNTILLAAENVTPDHPSGGVAVWRSRDQLYNEVEYLGFIPSRLTNALATAARQMSDRIYVVSVYTDGANITVAGYSSEFVLQDITVEVDALVA
What is the function of this protein?
Part of the gene cluster that mediates the production of the antimicrobial trichothecene harzianum A (HA) that plays a role in Botrytis cinerea antagonistic activity and plant defense priming (PubMed:21642405).  The biosynthesis of harzianum A begins with the cyclization of farnesyl diphosphate to trichodiene and is catalyzed by the trichodiene synthase TRI5 (PubMed:21642405).  Trichodiene undergoes a series of oxygenations catalyzed by the cytochrome P450 monooxygenase TRI4.  TRI4 controls the addition of 3 oxygens at C-2, C-11, and the C-12, C-13-epoxide to form the intermediate isotrichodiol (PubMed:21642405).  Isotrichodiol then undergoes a non-enzymatic isomerization and cyclization to form 12,13-epoxytrichothec-9-ene (EPT) which is further converted to trichodermol by the cytochrome P450 monooxygenase TRI11 via C-4 hydroxylation (PubMed:21642405).  The last step of HA synthesis is esterification of an octatriendioyl moiety to the C-4 oxygen of trichodermol.  The octatriendioyl moiety is probably produced by the polyketide synthase TRI17 and the esterification performed by the trichothecene O-acetyltransferase TRI3 (Probable).
What are the official names of this protein?
Trichothecene biosynthesis protein 14.
What is the protein family that this protein belongs to?
Belongs to the TRI14 family.
Protein: SRTA_STRP1
Sequence: MNNTIKDFDLDLKTNKKDTATPYVGSRYLCTPGSCWKLVCFTTTVK
What is the function of this protein?
Lanthionine-containing peptide antibiotic (lantibiotic) active on certain Gram-positive bacteria.  The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores (By similarity).
What are the official names of this protein?
Lantibiotic streptin.
What is the protein family that this protein belongs to?
Belongs to the type A lantibiotic family.
Protein: HYCI_ECO57
Sequence: MTDVLLCVGNSMMGDDGAGPLLAEKCAAAPKGNWVVIDGGSAPENDIVAIRELRPTRLLIVDATDMGLNPGEIRIIDPDDIAEMFMMTTHNMPLNYLIDQLKEDIGEVIFLGIQPDIVGFYYPMTQPIKDAVETVYQRLEGWEGNGGFAQLAVEEE
What is the function of this protein?
Protease involved in the C-terminal processing of HycE, the large subunit of hydrogenase 3.
What are the official names of this protein?
Hydrogenase 3 maturation protease, HycI protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase A31 family.
Protein: ATPA_STAA3
Sequence: MAIKAEEISALLRSQIENYESEMSVTDVGTVLQIGDGIALIHGLNDVMAGELVEFHNGVLGLAQNLEESNVGVVILGPYTGITEGDEVKRTGRIMEVPVGEELIGRVVNPLGQPIDGQGPINTTKTRPVEKKATGVMDRKSVDEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTTIAIDTILNQKDQGTICIYVAIGQKDSTVRANVEKLRQAGALDYTIVVAASASEPSPLLYIAPYSGVTMGEEFMFNGKHVLIVYDDLTKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDDLGGGSITALPIIETQAGDISAYVPTNVISITDGQIFLQSDLFFSGVRPAINAGQSVSRVGGSAQIKAMKKVAGTLRLDLASYRELESFAQFGSDLDEFTASKLERGKRTVEVLKQDQNKPLPVEHQVLIIYALTKGYLDDIPVVDITRFEDELNHWAESNATELLNEIRETGGLPDAEKFDTAINEFKKSFSKSE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YHAM_ECODH
Sequence: MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAELEGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQAIADAKALLAAGKVSVKIQEPCDEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHDGVVFTQQACVAEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEGLSGKWGLHIGATLEKQCERGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQGITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAAGMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR
What are the official names of this protein?
UPF0597 protein YhaM.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: KDGT_ECODH
Sequence: MQIKRSIEKIPGGMMLVPLFLGALCHTFSPGAGKYFGSFTNGMITGTVPILAVWFFCMGASIKLSATGTVLRKSGTLVVTKIAVAWVVAAIASRIIPEHGVEVGFFAGLSTLALVAAMDMTNGGLYASIMQQYGTKEEAGAFVLMSLESGPLMTMIILGTAGIASFEPHVFVGAVLPFLVGFALGNLDPELREFFSKAVQTLIPFFAFALGNTIDLTVIAQTGLLGILLGVAVIIVTGIPLIIADKLIGGGDGTAGIAASSSAGAAVATPVLIAEMVPAFKPMAPAATSLVATAVIVTSILVPILTSIWSRKVKARAAKIEILGTVK
What is the function of this protein?
Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
What are the official names of this protein?
2-keto-3-deoxygluconate permease, KDG permease.
What is the protein family that this protein belongs to?
Belongs to the KdgT transporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y8038_DICDI
Sequence: MMQRVAKLSVQTASRVSFKTCTNNFSAATATKSTSSGSVPSFFTESTSTPLNQSKTNTSTLNKSSKLNNNLIDNIMYVYFIY
What are the official names of this protein?
Putative uncharacterized protein DDB_G0288657.
Protein: SKI28_ARATH
Sequence: MKTELEEEEEEEWRSVHEVLLIVLPYLHSLFELLSMIRVSRSLRDAIRDETALWTKLVIEPPLSSRLTDDILSEFSSKSAGKLKTLILRQCLMVTNKGLRRVVDANPLITKIIVPGCSGLTPEGIMECVESLSKNNHKLETLHINGVNGFTKQHLSALYTYLSSEGTIDLEVCPKCDEVRMIPSCSRESCNQKQRKCRGCWLCIPRCAECAVCLVGSDTESQEAACGNDDVLCLECWLVLPKCRFCNKPYCTNHSSRRHEIAITDAASRPSFECEACYYRAGTNPYEVDYQI
What is the function of this protein?
Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).  Required during the endosperm development in embryos.
What are the official names of this protein?
F-box protein SKIP28, Protein MATERNAL EFFECT EMBRYO ARREST 11, SKP1-interacting partner 28.
Protein: ISPD_LEPIN
Sequence: MKSLFLSEKIYVLILAGGTGSRMGSKIPKQFLELNGEPILIHSLKRFQNWGKQKRIVLVSHFESIPKIESICASYLENEDRIVQGGENRHSSMLCGLSVLDFKDEDIILVHDAARPFVLADELDSLCEKVRSDGIATLASRTSETVLEELNGKTVSFLDREHVWFMKTPQGIRGDVLKELLTFSVDSIPTDLCSWALTFGKTSSIVESNPLNLKITRKEDLDLAEVFSSLFQKISSDI
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: YBEY_PSEPK
Sequence: MLELDIQRATDAATPEDAALRRWCELALRQRSADSEMTIRLVDEAEGRELNHTYRHKDYATNVLSFPADVPDDLLDIPLLGDLVICVAVVEREAAEQGKSLEAHWAHLVIHGCLHLLGYDHIEDEEAEEMESLERELLAELGHPDPYADDETDTITH
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IAP2_OSHVF
Sequence: MDIVPISPYERMRPLRESKELRIKSFDDHRWPHKNNPVMTKNMIENYFYYIGINDKIQCVHCGGVISGFLEEDTHRISYEHRRHFPKCPVGKYRHPGYHLDAERLKSFKNWRYENIVRKMDLVAAGLFYTGIEDRCACHQCGNELYEWEAGDNPKEEHKRLFPDCKLSSY
What is the function of this protein?
May act as an apoptosis inhibitor.
What are the official names of this protein?
Putative apoptosis inhibitor ORF87.
Protein: PUR1_CHICK
Sequence: MELEELGIREECGVFGCIAAGVWPTELDVPHVITLGLVGLQHRGQESAGIVTSDGESSQAFKVHKGMGLINHVFNADSLKKLYVSNLGIGHTRYSTSGISELQNCQPFVVETLHGKIAVAHNGELTNAVRLRRKLMRHGVGLSTSSDSELITQLLAFTPPLENDDTADWVARIKNLMNETPTSYSLLIMHKDIIYAVRDPYGNRPLCIGRLIPVGDINGKGKDNSETEGWVVSSESCSFLSIGAEYYREVLPGEIVKISRYDVQTLDVVPRPEGDPSAFCIFEYVYFARPDSIFEGQMVYSVRRRCGQQLAIEAPVEADLVSTVPESATPAALGYAQKCGLPYVEVLCKNRYVGRTFIQPNMRLRQLGVAKKFGVLSDNFKGKRVVIIDDSIVRGNTISPIIKLLRESGAKEVHIRVASPPIRFPCYMGINIPTKEELIANRPEFHDLANYIGADSVVYLSVEGLVSSVQESIKARKENENSLKTQKSRVGKIGHCTACLTGDYPVELEW
What is the function of this protein?
Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
What are the official names of this protein?
Amidophosphoribosyltransferase, ATase, Glutamine phosphoribosylpyrophosphate amidotransferase, GPAT.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
Protein: CFP32_MYCTU
Sequence: MPKRSEYRQGTPNWVDLQTTDQSAAKKFYTSLFGWGYDDNPVPGGGGVYSMATLNGEAVAAIAPMPPGAPEGMPPIWNTYIAVDDVDAVVDKVVPGGGQVMMPAFDIGDAGRMSFITDPTGAAVGLWQANRHIGATLVNETGTLIWNELLTDKPDLALAFYEAVVGLTHSSMEIAAGQNYRVLKAGDAEVGGCMEPPMPGVPNHWHVYFAVDDADATAAKAAAAGGQVIAEPADIPSVGRFAVLSDPQGAIFSVLKPAPQQ
What is the function of this protein?
May function as a glyoxylase involved in the methylglyoxal detoxification pathway (PubMed:20975714).  Induces maturation of dendritic cells in a TLR2-dependent manner, causing increased expression of cell-surface molecules (CD80, CD86, MHC class I and II) and pro-inflammatory cytokines (TNF-alpha, IL-6, IL-1 beta and IL-12p70).  Acts via both the NF-kappa-B and MAPK signaling pathways.  Induces Th1-polarized immune responses (PubMed:22415304).
What are the official names of this protein?
Putative glyoxylase CFP32, 27 kDa antigen Cfp30B.
What are the subcellular locations of this protein?
Secreted.
Protein: COW_CONVR
Sequence: MGKLTILVLVAAVLLSTQVMVQGDGDQPADRNAVRRDDNPGGLSGKFMNVLRRSGCPWHPWCG
What is the function of this protein?
Its target is unknown, but this toxin may modulate voltage-activated calcium channels (Cav) or calcium-dependent potassium channels (KCa).
What are the official names of this protein?
Contryphan-Vi, Contryphan-R-like.
What is the protein family that this protein belongs to?
Belongs to the O2 superfamily. Contryphan family.
What are the subcellular locations of this protein?
Secreted.