PharMolix/UniProtQA huggingface dataset:
Protein: TRMB_ALISL
Sequence: MTEVTKNDFTEEGKIVRKIRSFVRREGRLTKGQEGAITECWSTMGIDFVEQVLDWNEVFGNNNPVVLEIGFGMGASLVEMAQKAPDVNFLGIEVHRPGVGACLAAAKEAGVTNLRVMCHDAVEVFESMIPDSSVTTLQLFFPDPWHKARHHKRRIVKAEFAEMIRPKLNAEGVFHMATDWENYAEHMIEVMNAAPGYENIATDGDYIPRPDERPLTKFEARGHRLGHGVWDIKFRRNA
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: SPEH_CLOTE
Sequence: MNNLGRHILAEIYGCDELILNDKEYIERIMVDSALKSGAEVREVAFHKFSPQGVSGVVIISESHLTIHTWPELGYAAVDVFTCGDRVNPWDACNYMGEKLNAKNITATEVKRGIFEQPVAVKASNE
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: MNME_GLUOX
Sequence: MTRSSLPDAPDNTPQVIFALATGPSRAAIAIMRASGPGSDAILKALCNGRLPAPRRVSLRTLRHNGEVLDHAVALWLPGPNSYTGEDGFELHLHAGPAIIARIADALTDLGARPAEPGEFTRRAVQKGRLDLLQAEAIADLVDAETESQRKQALRQADGALSRLYDDWAQRLRLVLAHQEALIDFPDEELPQDVEDGLIEELSKLQTEMSAHLQDNRGELMRQGLTVVIAGSPNVGKSSLLNALSGTDAAIVTHRAGTTRDAIALDWVLDGVRLRLIDTAGLRETEDEIEAEGIRRALFHVKQADVVLHLIGPDESLDTLSGQEIPIRTKIDIAPAPPGMLGISTQSGEGLAALRQILSERVAELMAGSAAPPLTRARHRAGIQEAVTHLDHARTATWPELRGEELRLSMLALGRLTGRVDVESLLDAIFGQFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAE_BRUME
Sequence: MDGQPTCPLSISVRSEDFDIAAEIDRIGKNRREIGAIVTFTGLCRDEDGQLAALELEHYPGMAQAEISRMAKQALERWPLNGLTIIHRYGLIKPGENIVLVVAASRHRHAAFEAASFLMDYMKTNAPFWKREHLADGTAGGWVSSKEEDEESRKRWEEPRKSE
What is the function of this protein?
Converts molybdopterin precursor Z into molybdopterin.  This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group.  The sulfur is provided by MoaD (By similarity).
What are the official names of this protein?
Molybdopterin synthase catalytic subunit, MPT synthase subunit 2, Molybdenum cofactor biosynthesis protein E, Molybdopterin-converting factor large subunit, Molybdopterin-converting factor subunit 2.
What is the protein family that this protein belongs to?
Belongs to the MoaE family.
Protein: RL28_PSELT
Sequence: MAKRCEICGKGPVAGKNVSHSNRHTRRMFRPNLQKIRVITEDGTVRTMRVCTRCLKAGKVQKATA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: PHNC_BACCZ
Sequence: MIEFRNVSKVYPNGTKGLNNINLKIQKGEFVVMVGLSGAGKSTLLRSVNRLHEITEGEIMIEGESITAAKGKGLRRMRRDIGMIFQSFNLVKRSTVLKNVLAGRVGYHSTLRTTLGLFPKEDLELAFQSLKRVNILEKAYARADELSGGQQQRVSIARALAQEAKIILADEPVASLDPLTTKQVLDDLKKINEDFGITTIVNLHSIDLARQYATRIIGLHAGEIVFDGLVEEATDEKFAEIYGDVAQKSKLLEVAVK
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GREA_STRS2
Sequence: MAEKTYPMTLEEKEKLEKELEELKLVRRPEIVERIKIARSYGDLSENSEYEAAKDEQAFVEGQISTIETKIRYAEIVNSDAVAADEVAIGKTVTVQEVGETEEEVYHIVGAAGADVFANKISNESPIGHALIGKKTGDVATIETPAGSYDVKILKVEKTK
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: YCIB_RICRS
Sequence: MLKFLSEIGPVIAFFAGFFYGGGIQHATLYMLITSVICITLCYVIDKKVSKLSIISTTVLLVSGSITLISGDSMYIKIKPTILYVIFGIIFLMSGIRKNPFIKYALESIVRLKEESWITLSYRTAAFFFFMAVVNEVVWRNCSDETWVKFKVFGVIPITFIFILLQLPLLLKNKLPDSKI
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y2473_ERWT9
Sequence: MFGKAGLGNLMKQAQQMQEKMAQVQEEIAEMEVTGESGAGLVKVTINGAHSCRRVEVDPSLLEDDKDMLEDLVAAAFNDAARRISEAQKDKMASVSNGMSLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein ETA_24730.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PRGC1_MOUSE
Sequence: MAWDMCSQDSVWSDIECAALVGEDQPLCPDLPELDLSELDVNDLDTDSFLGGLKWCSDQSEIISNQYNNEPANIFEKIDEENEANLLAVLTETLDSLPVDEDGLPSFDALTDGAVTTDNEASPSSMPDGTPPPQEAEEPSLLKKLLLAPANTQLSYNECSGLSTQNHAANHTHRIRTNPAIVKTENSWSNKAKSICQQQKPQRRPCSELLKYLTTNDDPPHTKPTENRNSSRDKCASKKKSHTQPQSQHAQAKPTTLSLPLTPESPNDPKGSPFENKTIERTLSVELSGTAGLTPPTTPPHKANQDNPFKASPKLKPSCKTVVPPPTKRARYSECSGTQGSHSTKKGPEQSELYAQLSKSSGLSRGHEERKTKRPSLRLFGDHDYCQSLNSKTDILINISQELQDSRQLDFKDASCDWQGHICSSTDSGQCYLRETLEASKQVSPCSTRKQLQDQEIRAELNKHFGHPCQAVFDDKSDKTSELRDGDFSNEQFSKLPVFINSGLAMDGLFDDSEDESDKLSYPWDGTQPYSLFDVSPSCSSFNSPCRDSVSPPKSLFSQRPQRMRSRSRSFSRHRSCSRSPYSRSRSRSPGSRSSSRSCYYYESSHYRHRTHRNSPLYVRSRSRSPYSRRPRYDSYEAYEHERLKRDEYRKEHEKRESERAKQRERQKQKAIEERRVIYVGKIRPDTTRTELRDRFEVFGEIEECTVNLRDDGDSYGFITYRYTCDAFAALENGYTLRRSNETDFELYFCGRKQFFKSNYADLDTNSDDFDPASTKSKYDSLDFDSLLKEAQRSLRR
What is the function of this protein?
Transcriptional coactivator for steroid receptors and nuclear receptors (PubMed:15744310, PubMed:12754525, PubMed:23217713, PubMed:9529258).  Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter (PubMed:15744310, PubMed:12754525, PubMed:23217713, PubMed:9529258).  Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis (PubMed:15744310, PubMed:12754525, PubMed:23217713, PubMed:9529258).  Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism (PubMed:15744310, PubMed:12754525, PubMed:23217713, PubMed:9529258).  Acts as a key regulator of gluconeogenesis: stimulates hepatic gluconeogenesis by increasing the expression of gluconeogenic enzymes, and acting together with FOXO1 to promote the fasting gluconeogenic program (PubMed:12754525).  Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner (By similarity).  Also involved in the integration of the circadian rhythms and energy metabolism (PubMed:17476214).  Required for oscillatory expression of clock genes, such as BMAL1 and NR1D1, through the coactivation of RORA and RORC, and metabolic genes, such as PDK4 and PEPCK (PubMed:17476214).
What are the official names of this protein?
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, PGC-1-alpha, PPAR-gamma coactivator 1-alpha, PPARGC-1-alpha.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body.
Protein: YR640_MIMIV
Sequence: MASYQSINFRREAILSGRPYPYYYPYVSQIPCISNSCEDHRIQADPNIIYSYEGTQAFDWSNGQCHDPTHNRSTCISNVYYPTNPIFDYCYYGETPFQDPSYQLGFIVREIVVNIIDVPDLRDPVEYMETMAPIGNSESLQINFVLNNQNKLSENNQSNPQINSQINPQMNPRINSQINTQRDNLQPEIYTNNDEPTLSAPVKSVLYKDPIDRIRKVTNCPQVTQDPGLIEPRNLIIVCDTIWVCTPGFLRAYNLLGVPTGRKIGTFGIGGNNVYPSSIAYNDNQCLFPIQKGSKCASSTMIIATLDGTINAYNPIINPENSILVIDNSSRQAMYTGVAICGCRVYLTDFYNQQIDVYDDKFILLPEFSFVGDDECDPIPEYFSPYNIVNICDQLYVTFVQQDPYNNTLEFDGTGLGYINIYTPDGIFIRRFASGCVLNVPYGLIEAPSCYGYPSGSILVANYGSGNINVFDIHGKWISNLKDGFGTDLYIEGLRGITHASCCPKTVYWTSCVNHKINKLGTINTSTNNC
What are the official names of this protein?
Uncharacterized protein R640.
What is the protein family that this protein belongs to?
Belongs to the mimivirus R640 family.
Protein: MMPS4_MYCBO
Sequence: MLMRTWIPLVILVVVIVGGFTVHRIRGFFGSENRPSYSDTNLENSKPFNPKHLTYEIFGPPGTVADISYFDVNSEPQRVDGAVLPWSLHITTNDAAVMGNIVAQGNSDSIGCRITVDGKVRAERVSNEVNAYTYCLVKSA
What are the official names of this protein?
Probable transport accessory protein MmpS4, PGB14T-X.
What is the protein family that this protein belongs to?
Belongs to the MmpS family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SECA_ACIC5
Sequence: MIGSVLTKVFGTSNERVVKRLLPIVEQIGALEPEIEKLSDEQLRAKTAEFRAYIAKAVEGVDDEDEQHKAIQRALDDLMPEAFAVVREAGRRVLHMRHFDVQLIGGMVLHQGKIAEMKTGEGKTLVATLPCYLNALAGRGVHVVTVNDYLAKRDAEWMGKIYEFLGLTVGVIVHDLDDEQRRQAYAADITYGTNNEFGFDYLRDNMKFDLKDCVQRKHFYCIVDEVDSILIDEARTPLIISGPTDQTTDKYVRVNRIIPALEQGEEIEKGEEKILTGDFVVDEKHKTISVTDEGWEKIEQLLGIGNIADPENWDLKHHVETAIKAHSLYKRDVQYVVKDGEVIIVDEFTGRLMPGRRWSDGLHQSVEAKEGVNIRREDQTLATITFQNYFRLYKKLSGMTGTAETEAAEFDKIYKLEIVVIPTNRPLLRVENPDVVFRTTQEKYFAVADQIAELNKNNQPVLVGTTSIEKSELLSQILVRKGVKHVVLNAKYHEREAEIVAQAGRLGMVTIATNMAGRGTDILLGGNADFMAKQELLKKGMARSISPAEGAINPMAAQGMLRFYYQGQEFETTQENWDRVFAQHSASVAQEREQVLAAGGLYIIGTERHESRRVDNQLRGRAGRQGDPGASRFYLSLEDDLMRIFAREWVSTLLQRLGMEEGVPIESRMISNRIEKAQMAVEGQNFEARKHLLEYDDVMNKQREAVYGLRNQLLAGLDQKELIVEDYVPNILSGIFDEYAPEKQHADQWNWEEIRKKLIDHFGFDYQVDGLDVADLTRHELGEEVFSRLKERYLAKEQFIGEEPMRYHERMIMLSVLDGLWKDHLLNMDHLKEGIGLRGYGQQDPLIEYKRESFDMFEAMMNRFQEDTVRYLYLMQIVGPDGQPMQVPTRLRPADASPNGVVHAEPAPLNGSAPIPEQAAPPPPPAIPTRQPSTTIDAIEREFEKKKQQELSHARMAGGGDGSDAVNTRRVGEKVGRNDPCPCGSGKKYKKCHGAEA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: IF5A_HALMA
Sequence: MAREQTEVRELDEGSYVMIEDTPCKINSYSTAKPGKHGSAKARIDAKGVFDGKKRSLSQPVDAKVWVPIVNRKQGQVVSTDGNDAQVMDLDTYDTFTMRVPEDIDLQPDDEIEYLQYEEQRKITRS
What is the function of this protein?
Functions by promoting the formation of the first peptide bond.
What are the official names of this protein?
Translation initiation factor 5A, Hypusine-containing protein, eIF-5A.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_CHLTA
Sequence: MQTSRISSFFRGLVHLYRWAISPFLGAPCRFFPTCSEYALVALKKHPLRKSLFLIAKRLLKCGPWCIGGIDLVPRTSVEEYLSSPTPLAESPDDRTVPHTQETS
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL21_SHESA
Sequence: MYAVFQSGGKQHRVAPGHTVRLEKLEVATGSTVEFDQVLLIADGEKVHVGAPLVAGGKVVAEVVSHGRGEKVTIVKFRRRKHHDKKLGHRQWFTEVKITAINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: SPRT_SHIBS
Sequence: MKTSRLPIAIQQAVMRRLREKLAQANLKLGRNYPEPKLSYTQRGTSAGTAWLESYEIRLNPVLLLENSEAFIEEVVPHELAHLLVWKHFGRVAPHGKEWKWMMENVLGVPARRTHQFELQSVRRNTFPYRCKCQEHQLTVRRHNRVVRGEAVYRCVHCGEQLVAK
What are the official names of this protein?
Protein SprT.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPED_XANC8
Sequence: MVKPLPRLRLQGFNNLTKALSFNIYDVCYARTEEERQRYIEYIDEQYDADRLTQILTDVAEIIGANILNIARQDYDPQGASVTILISEEPVIDKKQAGKELISDAVVAHMDKSHITVHTYPETHPQEGIATFRADIDVATCGVISPLKALNYLIESLESDIVIMDYRVRGFTRDVKGKKHYIDHKINSIQHFLAKNVKSRYEMFDVNVYQENIFHTKMHLKDFDLDQYLFEERAKNLSFKERMKIETLLKREIEELFHGRNLSE
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: GLMS_STAES
Sequence: MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDGTKLFKEKGRIAELRKVADNSDEDGTLGIGHTRWATHGVPNYENSHPHQSTSGRFTLVHNGVIENYEELKAEYLSDVTFSSETDTEVIVQLVDYFSRQGLATEDAFTKVVKLLHGSYALGLLDDNDKDTIYVAKNKSPLLVGVGEGFNVIASDALAMLQTTNQYKEIHDHEIVIVKRDTVEIKDLEGHIQQRDTYTAEIDAADAEKGVYDHYMLKEIHEQPAVMRRIIQEYQDEKGNLKIDSEIINDVADADRIYIVAAGTSYHAGLVGKEFIEKWAGVPTEVHVASEFVYNMPLLSEKPLFIYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKNHGRETDVDLLRELAKVTTAIETIVDDAPKMEQIATDFLKTTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEDGTPVIGLATQENVNLSIRGNMKEVVARGAYPCMISMEGLNKEGDTYVIPQVHELLTPLVSVVTMQLISYYAALQRDLDVDKPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMKL_VIBC1
Sequence: MNQYLAVTSNGMENLLAEELTKLGIENAKPVQAGVKFKATNEQIYRCCLWSRLASRFVRVLSEFTCNDDMDLYLSTSSINWVNQFHSSKRFVVDFNGTNREIRNSQYGAMKVKDGIVDCFEKKGLPRPNISKERPDIRVHVRLHKDKAILGVDMVGSGLHQRGYRPESGRAPLRETLAAAIVMRCGWDGSQPLLDPMCGSGTLLIEAAMMAANMAPGVKRKQWGFEALEDFEPELWAEIKSEANVQARRGVKKVDAKFFGFDNDPNVLKVAQDNARRAGVEELITFAQGDAATITRPAGFEAGVIVSNPPYGERLGTEPGLIALYTAFGGQLKAEFGGCKASIFSSSDELLSCLRMRADKQFKLNNGALPCHQKNYSIAERSADEVKGADTNVQIAPDFSNRLKKNIGKIGKWARKEKLDCYRIYDADLPEYNVAIDVYGDQIVIQEYAAPKNIPEEKAKRRLTDIIRATIQVTGVEANKVVLKVREKQKGLSQYQKLGQVSETLEVNEYGVKLIVNLHDYLDTGLFLDHKITRRRLGEMAQGKDFLNLFAYTGSATVHAAVGGARSTTTVDMSNTYLNWAKDNMQLNGCVGRQHRFEQADCLQWLENAKGEYDLIFIDPPTFSNSKRMETSFDVQRDHIKLMTNLKRLLRAGGAIVFSNNKRHFKMDEAGLAELGLKAQNISSQTLPLDFSRNKQIHNCWLVTHAE
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YR311_MIMIV
Sequence: MKLKLIFKTIYADKDKTDLFYCVSKGIIYNKIKNKIVYQLKYTEIPRYFNFNLEFESYQSNKIYQSNTNTYKNTIIGSIYNLVLYIDIHNLFCDRFRINNKVLKILCYYLIIIQIRQLKTNKSYNITKENLPFKINDIINNPIQLIPWNLFLLGKNITLDLKNIKLVTNKQIPKKKFQKTGCIFESNNIDKLTHELRKKITTKSLIIIPTGFPKLWTNCSSITYTTYIDLVQLNDNFENKFKNKKMIHNIIVHECYIQYIPIIKKLIQYFVDCKSIWIINSLPLKYYISNDNNTEGKFTIGNVFKLANIWANFSTNDKKSYKTEIIRFIMADFNKLYFKINFPTDDLPVQIISPNILELNIFNEFRKFHMDWLSKLNNDKNNIYSSTSKHKNNRIKSKIYDCVMVLSLSVINNNDITIFFKNKIQKTLDINCKISKKIEKMIDVYISARKTSHHKINEKTPVDFTKIVNSLTQKKDKINSVISNYNRYQKNGFYDSIKDNDCPVCYDDDYIKTKLICGHTVCLTCVLNILPNSKGCPLCMEPININKMAIIRESIGESNNYSEMLDLLFKNLSNETLILTNLEETHNIMLYRGFNVWLLKCSFIAKKINFLSKITTVIILSSPLNSINDSDKLDFEMFQEYIKLVNPNISIKRIQLNIY
What are the official names of this protein?
Putative RING finger protein R311.
Protein: BIEA_MOUSE
Sequence: MSTEPKRKFGVVVVGVGRAGSVRIRDLKDPHSSAFLNLIGYVSRRELGSLDNVRQISLEDALRSQEVDVAYICTESSSHEDYIRQFLQAGKHVLVEYPMALSFAAAQELWELAAQKGRVLHEEHIELLMEEFEFLKREVAGKELLKGSLRFTASPLEEEKFGFPAFSGISRLTWLVSLFGELSLISATMENRKEDQYMKMTVQLETQNKSPLSWIEEKGPGLKRNRHISIHFKSGSLEEVPNVGVNKNIFLKDQDIFIQKLLGQVSAEDLAAEKKRILHCLELASDIQRLCHRKQ
What is the function of this protein?
Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor.  Uses the reactants NADH or NADPH depending on the pH; NADH is used at the acidic pH range (6-6. 9) and NADPH at the alkaline range (8. 5-8. 7).  NADPH, however, is the probable reactant in biological systems.
What are the official names of this protein?
Biliverdin reductase A, BVR A, Biliverdin-IX alpha-reductase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family. Biliverdin reductase subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: CADC_LISMN
Sequence: MTVDICEITCIDEEKVKRVKTGLETVEVTTISQIFKILSDETRVKIVYALLTENELCVCDLANIVEATVAATSHHLRFLKKQGIANYRKDGKLVYYSLANERVRDRIKLILLNFEGVGV
What is the function of this protein?
Metal-binding repressor for the cad operon.  Involved in resistance to heavy metals, such as cadmium, bismuth, zinc or lead.  Metal binding causes the repressor to dissociate from the DNA (By similarity).
What are the official names of this protein?
Cadmium resistance transcriptional regulatory protein CadC, Cadmium efflux system accessory protein.
Protein: MTLD_ACTPJ
Sequence: MNALHFGAGNIGRGFIGKLLADSGVFVTFADINQTQIDQINQNKQYGVKIVGDASRVEVVKNIAAINSKDEEAVIEQVKSVELITTAVGPNVLGFIAPLFAKALAARLEAGNTQPLNIIACENMVRGTSFFKAKIFENLTASQQAEIEKFVGFVDSAVDRIVPPAELNEADPLEVTVEEFSEWIVDKTQFKGQIPDIKGMELTDNLMAFVERKLFTLNTGHLISAYLGKQAGVKWIKEAIAIDSVKAAVKATMEESGAVLIKRYNFDPQAHAAYIEKILKRFANPYLNDDVNRVGREPIRKLSPNDRLIKPLLGTLEYGLPHKNLVNGVVMALQYRNEEDPQAVELAQFIADNGVAAAVEKYTGLTNQEVIDQVVALYN
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: RL16_STRSY
Sequence: MLVPKRVKHRREFRGKMRGEAKGGKQVDFGQYGLQATTSSWITNRQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKVMFEVAGVSEEIAREAFRLAGHKLPVKVKFVKREAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: TMX2_RAT
Sequence: MAVLAPLIALVYSVPRLSRWLARPYCLLSALLSIAFLLVRKLPPICNGLPTQREDGNPCDFDWREVEILMFLSAIVMMKNRRSITVEQHVGNIFMFSKVANAILFFRLDIRMGLLYLTLCIVFLMTCKPPLYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYNCSGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLPTLILFQGGKEVMRRPQIDKKGRAVSWTFSEENVIREFNLNELYQRAKKLSKGGDMSEEKPGNPTPTAVPDGENKKDK
What is the function of this protein?
Endoplasmic reticulum and mitochondria-associated protein that probably functions as a regulator of cellular redox state and thereby regulates protein post-translational modification, protein folding and mitochondrial activity.  Indirectly regulates neuronal proliferation, migration, and organization in the developing brain.
What are the official names of this protein?
Thioredoxin-related transmembrane protein 2, Thioredoxin domain-containing protein 14.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Mitochondrion membrane. Note=Localizes to endoplasmic reticulum mitochondria-associated membrane (MAMs) that connect the endoplasmic reticulum and the mitochondria.
Protein: RPA2_SCHPO
Sequence: MSFQTLERERTFKNPPKDGTSFPDLQKAVKPHVDSFNALTNAGLLNYAVKEIGEKCAFDSITQEEGGALKFGNKISFRVDEVQIAKPMLSSRERSSINRKVYPAEARERLTTYKSRLVLKFSWSVNGGPRQSEMREVGMIPIMVRSNRCHLEGLSPAELIAHKEESEEMGGYFIVNGIEKLIRMLILPKRNHPTAIIRPSFANRGTSYSQYGLSIRCVRPDQSSLTNTLHYLNNGVTMFRFHWRKNEYLIPSMMILKALLETSDKEIFEGIVGKDLGNTFLTDRVELMLRAYKSYGLYSQTETLQYLGSKFRVVLGVAEDLTDVEVGRFLLQKVVLVHLREAKDKFRLLLFMIRKLYALVAGECCADNPDSPQHQEILLGGFLYGQILKEKIEDWLNSIRAQINLDVRRSAPGVDFSDRKYLTRVFSKINNDIGTKLQYFLSTGNLVSNTGLDLQQATGYTVVAEKLNFYRFLSHFRMVHRGAFFAELKTTTVRKLLPEAWGFMCPVHTPDGSPCGLLNHLARKCEIVTHPSDVSQIPSLLLSLGVDPPSVVGHESGWGCVQLDGKIVGWCTYKLAKHVADVLRLMKIEYAVKLRNGTATEPAKVPLDLEIGYVPPSHNGQYPGLYLFSNPARMVRPVKHISTGELDMLGPFEQVYMDIACFPKEIVPKVSTHVEYSPTNVLSIVANMTPFSDFNQSPRNMYQCQMGKQTMGTPGTALRYRTDNKLYRLQTGQTPVVRPKLHNTYGLDHYPNGTNAVVAVISYTGYDMEDAMILNKSAHERGFGYGTVYKGESFDLSQKRRRGEPVVHHFGFAPGSTPRREWLQKLDADGLPFIGIKLEDGDPIVAYYDESTGQNFIETYHGTEPGFVDEVRLLGNDVGDSECQQIHVKLRITRSPIIGDKFSSRHGQKGICSQKWPTVDMPFTESGMQPDIIINPHAFPSRMTIGMFIESLAGKAGACHGLAQDSTPFIYSEQQTAADYFGEQLVKAGYNYHGNEPMYSGITGQEMKADIYIGVVYYQRLRHMVSDKFQVRTTGPIHNLTRQPVKGRKRAGGIRFGEMERDAVIGHGTSFLMQDRLMNCSDYAQSWVCRDCGSIISIMSTISMNGVGSASEVRCRSCAKPALGLEDTSDIWQDGSGKKFVGGTNTTLIALPSVFNYLTAELTAMNIKMMLEVK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors.  Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit.  Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity).
What are the official names of this protein?
Probable DNA-directed RNA polymerase I subunit RPA2, DNA-directed RNA polymerase I polypeptide 2, RNA polymerase I subunit 2.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: HBB_BLABR
Sequence: VHLTAEEKSLVTGLWGKVNVEEAGGEALGRLLVVYPWTQRFFDSFGDLSSASAVMGNPKVKAHGKKVLQSMGDGLANLDNLKGTFAKLSELHCDKLHVDPENFRLLGNVLVVVLARHFGKEFTPPVQAAFQKVVAGVATALAHKYK
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta.
What is the protein family that this protein belongs to?
Belongs to the globin family.