PharMolix/UniProtQA huggingface dataset:
Protein: PUMY_ARATH
Sequence: MASSLAQSRISNLQNHLSPLEANNKLRSLVKISPQVSEALSNGRAVVALESTIISHGMPYPQNLQTAKEVESIVRENGAIPATIAILNGVPCIGLSEEELERLASLGKSVQKTAGRDIANVVATRGNGATTVSATLFFASMVGIQVFVTGGIGGVHRHANHSMDISSDLTALGRTPIAVISAGVKSILDIPKTLEYLETQEVYVAAYKSDEFPAFFTEKSGCKAPSRVNSPEDCARVIDANMKLNRQAGILFAIPIPKHHSAAGNLIESATQRALTEAREQNVTGNAETPFLLARVNELTGGTSLAANIALVKNNALIGSQIAVALSQLM
What is the function of this protein?
Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (PubMed:31907295).  Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway (PubMed:31907295).  Acts together with the pseudouridine kinase PUKI in the peroxisome to prevent toxic pseudouridine monophosphate accumulation (PubMed:31907295).  Can catalyze the formation of pseudouridine 5'-phosphate (reverse reaction) in vitro, with a catalytic efficiency 4 times lower than the hydrolysis reaction (PubMed:31907295).
What are the official names of this protein?
Pseudouridine-5'-phosphate glycosidase, PsiMP glycosidase, Pseudouridine monophosphate glycosidase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine-5'-phosphate glycosidase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: EBLN1_HUMAN
Sequence: MSRPRNNPQTSSPQDSTKDGSSFHYFQGRFELSGKSRQYPADALEPQPGIGDVKVIEKATKSMLDPAQRSHFYLVTPSLVFLCFIFDGLHKALLSVGVSKRSNIVIGNENKETGTLYASKFEDVLPTFTALEMSSILRHCCDLIGIAAGSSDPICTNSLQVQRQFKAMMISIGRPLHSESADLLISYNAGPAIDWINSRPWVGGLMFTFLFGEFESPACELLDQVKVVASKAQMMTYYTVRMFLDQCVDGSTALPAVVLEIPVFEQKKPLAKKVLGDFFEFGGVLRHPVIGVLSPQMFPNLATAANYWAKRRNSTFSGFEALDIIPGSTITFPVLQMASAQKISRGSDMDPYTLNILRGYGISGFE
What is the function of this protein?
May act as an RNA-binding protein.  Highly homologous to the bornavirus nucleocapsid N protein that binds viral RNA and oligomerizes (By similarity).
What are the official names of this protein?
Endogenous Bornavirus-like nucleoprotein 1, Endogenous Borna-like N element-1, EBLN-1.
Protein: Y598_CHLL3
Sequence: MRIHDLDPENRPRERFLSSGPSALSSAELLALVLRSGTRHLNIVDTCQRIIAENGLERLASMTLGELQKTPGIGQAKAMQIVAIFELNNRLHHTRNTNRRVQGAKDVFEYMSGRIPDETQEHLFVLHLNTKNQVTKCVRVTVGTLNASLIHPREVFKSAIRESAHAIILVHNHPSGDTEPSNADRQVTTLLKQASAVIQIDLLDHVIIGKTSWFSFRESNLLG
What are the official names of this protein?
UPF0758 protein Plut_0598.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: MUTS_AQUAE
Sequence: MEKSEKELTPMLSQYHYFKNQYPDCLLLFRLGDFYELFYEDAYIGSKELGLVLTSRPAGKGKERIPMCGVPYHSANSYIAKLVNKGYKVAICEQVEDPSKAKGIVKREVVRVITPGTFFERDTGGLASLYKKGNHYYVGYLNLAVGEFLGAKVKIEELLDLLSKLNIKEILVKKGEKLPEELEKVLKVYVSELEEEFFEEGSEEILKDFGVLSLQAFGFEEDTYSLPLGAVYKYAKTTQKGYTPLIPRPKPYRDEGFVRLDIKAIKGLEILESLEGRKDISLFKVIDRTLTGMGRRRLKFRLLSPFRSREKIERIQEGVQELKENREALLKIRQILEGMADLERLVSKISSNMATPRELVYLKNSLKKVEELRLLLLELKAPIFKEILQNFEDTKKIINDIEKTLVEDPPLHVKEGGLIREGVNAYLDELRFIRDNAETYLREYEKKLRQETGIQSLKIGYNKVMGYYIEVTKPNLKYVPSYFRRRQTLSNSERFTTEELQRLEEKILSAQTRINDLEYELYKELRERVVKELDKVGNNASAVAEVDFIQSLAQIAYEKDWAKPQIHEGYELIIEEGRHPVIEEFVENYVPNDTKLDRDSFIHVITGPNMAGKSSYIRQVGVLTLLSHIGSFIPARRAKIPVVDALFTRIGSGDVLALGVSTFMNEMLEVSNILNNATEKSLVILDEVGRGTSTYDGIAISKAIVKYISEKLKAKTLLATHFLEITELEGKIEGVKNYHMEVEKTPEGIRFLYILKEGKAEGSFGIEVAKLAGLPEEVVEEARKILRELEEKENKKEDIVPLLEETFKKSEEAQRLEEYEEIIKKIEEIDIGNTTPLQALLILAELKKKCSFSKKESGA
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity (By similarity).
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: A0926_ARTBC
Sequence: MSVLSRAVQLAFVALGLCLFFSNLVAAQPIAGPSLGVSVKSVNGVCRASKPCELEVTVRNTNTKKPATVLNWNTPLDPYADQLGVFEVRDSKGAVVPLDFIQIRRITPPPASDLVEIKAASSVKVKVALETLSRAELPAGTKYTITATGWWQAVWDQPKEQVVQSHLQELSGAFSGNFNSNSVQVTKVCSSSSPQQ
What are the official names of this protein?
Uncharacterized secreted protein ARB_00926.
What are the subcellular locations of this protein?
Secreted.
Protein: DD19A_MOUSE
Sequence: MATDSWALAVDEQEAAVKSMSSLQIKEEKVKADTNGVIKTSTTAEKTEEEEKEDRAAQSLLNKLIRSNLVDNTNQVEVLQRDPSSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPMMLAEPPQNLIAQSQSGTGKTAAFVLAMLSRVEPADRYPQCLCLSPTYELALQTGKVIEQMGKFHPELKLAYAVRGNKLERGQKVSEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNIIKLKREEETLDTIKQYYVLCNNREEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN
What is the function of this protein?
ATP-dependent RNA helicase involved in mRNA export from the nucleus.  Rather than unwinding RNA duplexes, DDX19 functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins.
What are the official names of this protein?
ATP-dependent RNA helicase DDX19A, DEAD box RNA helicase DEAD5, mDEAD5, DEAD box protein 19A, Eukaryotic translation initiation factor 4A-related sequence 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Note=Associates with the nuclear pore complex cytoplasmic fibrils.
Protein: SELO_ECODH
Sequence: MTLSFVTRWRDELPETYTALSPTPLNNARLIWHNTELANTLSIPSSLFKNGAGVWGGEALLPGMSPLAQVYSGHQFGVWAGQLGDGRGILLGEQLLADGTTMDWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVTSDSPVYRETAEPGAMLMRVAPSHLRFGHFEHFYYRRESEKVRQLADFAIRHYWSHLADDEDKYRLWFSDVVARTASLIAQWQTVGFAHGVMNTDNMSLLGLTLDYGPFGFLDDYEPGFICNHSDHQGRYSFDNQPAVALWNLQRLAQTLSPFVAVDALNEALDSYQQVLLTHYGERMRQKLGFMTEQKEDNALLNELFSLMARERSDYTRTFRMLSLTEQHSAASPLRDEFIDRAAFDDWFARYRGRLQQDEVSDSERQQLMQSVNPALVLRNWLAQRAIEAAEKGDMTELHRLHEALRNPFSDRDDDYVSRPPDWGKRLEVSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: BU107_SCHPO
Sequence: MSVRKRYKVTYVLDSCNDQLGHRLDANCLVLGRYFSEQGSAPVTRALYSGGRDGQLFGWDIGYDYGKASQPLAKIQAHSAWVNDIALTHDSEGVISCSSDSTVKLWKPHVLNASCLSTIGEHTDYVKRVSIPKYSKSPLVASGGLDKRIIVWDYNVGQEVMRFEQLPDCSLVVGPRSGVYSLAANNNIIANGGLQKDIQLWDCVSKKRITDLVGHTDNVRDILISDDGRTILTASSDATIKLWSLRAQKCLFSFIAHSDSVWALYSEHPDLKVFYAGDRSGLITRTDIRNQPNNQSCTAICKQDAPVSDIVARQSFIWSTSRDGSILRWKDEPLFNQDVGAALSKHTSSHLSVSSDCPSRHSSDIRNHSCPTLYHDDAEDIYYDLHHTESYSNINLTKTPDYVIHGGIGLLKYRMLGDRRHVLTEDAVGNKCLWDILACKQAGEFDKSEDFEKIVQSLDTVQAIPRWASVNCLLGILAVTLDENHYMDAEIYADECPLLKVDSPSDKRINLGVWILKNLFREFIDAELHRDLKFRQNLDVVRSEAKKQIEAQREEARKGNVNMPSALSPLRIRSRPSPLSLPPEPLLSPTIDYSATPFPLEPPPESPGPSLQIPSNNPVYTNLTDTDSMMGAPDYFSIPARQNRNRKPHTEVVGSPTVVRTKEIIPPKVTREGSFMGRLKKLGRSKSSKSLQTDFMKASVERAASSRVFSTGTSVTSPQALSKTNNTVNNAANTENNTLAKDKQQTSEASSPGTPRELKTTGELIEDLHEQYVHFKDKDTVLSLMKPPNDDTFPMLNLSSQITVIISEESPEAGNSRDIYRSTLENMADDIDLLENIMPFWLGRLLLLNEFPSKTAPTVNFTLQPFPGSGLPLIVNENTRLSASAMLRAQKIMDYSYSKLSQQRKDVSSLQFRCKDVVVTPKMTLATVKARIWRSGDDVVFHYDVAPRSVSEIVDKTQSLNI
What is the function of this protein?
Required for the ubp9 recruitment to septa and cell tips but also for its enzymatic activity at these specific locations.
What are the official names of this protein?
UBP9-binding protein bun107, Binding ubp9 protein of 107 kDa.
What are the subcellular locations of this protein?
Cytoplasm. Cell septum. Cell tip.
Protein: RACD_ENTH1
Sequence: MSAAPTDAKSVKLVVVGDGAVGKTCLLICYTTNEFPKDYVPTVFDNYMAPMTVDGEPINLGLWDTAGQEDYEQLRPLSYPNTDLFLLCFSVISRTSFNNISSKWLPEIKHYEPKCKMMVVGTKTDCRNDEAMIRKLADENQKPITTEEGEKLAKDIKAICYMECSALTRSGLNQVFDEAIHIVLNKNQSSKKSSKKCALL
What is the function of this protein?
Small GTPase which cycles between active GTP-bound and inactive GDP-bound states.
What are the official names of this protein?
Rho-related protein racD.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
Protein: BPPBG_BOTFO
Sequence: QARPRHPKIPP
What is the function of this protein?
This peptide both inhibits the activity of the angiotensin-converting enzyme (ACE) and enhances the action of bradykinin by inhibiting the peptidases that inactivate it.  It acts as an indirect hypotensive agent (By similarity).
What are the official names of this protein?
Bradykinin-potentiating peptide 11g, BPP-11g.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-potentiating peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: YH11A_YEAST
Sequence: MESQQLSNYPHISHGSACASVTSKEVHTNQDPLDVSASKIQEYDKASTKANSQQTTTPASSAVPENLHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPETY
What is the function of this protein?
Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome.  The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules.  CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity).
What are the official names of this protein?
Transposon Ty1-H Gag polyprotein, Gag-p49, Transposon Ty1 protein A, TY1A, TYA, p58.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_FRATN
Sequence: MNKIAIYPGTFDPITNGHVDLVERALNIFDEIVVAVSTAYGKNTLFDIRIREQMIKEVFKDNQRVKVVSFQGLLVDTAVKHNACAIVRGLRAVSDFDYEFQMSSMNNKLNSDIQTIFLTPSEKFSCISSTLVRAVAIHNYKRVDEFVPECVFREIKLKYSKE
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIDNA_XENLA
Sequence: MEQQPSVPRSCTNVARETPMNLNIQSTTGTRYELSVPPDETVDGLKRRISQRLKVPKDRLTLLHRETRLSSGKLQDLGISDGSRLTLLPSVEAGLMSQMSRPEQSVMQALESLTETQVNDFLSGRSPLTLALRVGDHMMFVQLQLAAQQSGSSHLQHRHVITRGAETSASPQYRTLHTSTSAVSHLASCTPGPTPPTTLSPTSSTHCNGPHSSPLTTSVFRSHGEGVAVSPCAEQAPCSTRGTEGTSSSPSSRSRKPGAIIESFVNHAPGVFSGTFSGTLHPQCQDSAGRPRRDIGTILQILNDLLSATRHYQGMPPSLTTLRCHTQCASQARNAKATSPQSTSPQQTTHPVGHCQTQTRTYKPSGDRLRQTENRATRCKVERLQLLMHQKRLRRKARRDSRAPYHWMPTRKSSRTSSNSSTSSGEGSLEIDFEDSLWKPDVKAELNSEFVVA
What is the function of this protein?
Facilitates ubiquitin-independent proteasomal degradation of polycomb protein CBX4.  Plays a role in inhibiting the activity of glucokinase GCK and both glucose-induced and basal insulin secretion.
What are the official names of this protein?
Midnolin-A, Midbrain nucleolar protein A.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Nucleus, nucleolus. Note=Detected in the nucleus and nucleolus with no expression in the cytoplasm. However, a later study finds expression in the nucleus and cytoplasm with no expression in the nucleolus.
Protein: INS_MYXGL
Sequence: MALSPFLAAVIPLVLLLSRAPPSADTRTTGHLCGKDLVNALYIACGVRGFFYDPTKMKRDTGALAAFLPLAYAEDNESQDDESIGINEVLKSKRGIVEQCCHKRCSIYDLENYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
What are the official names of this protein?
Insulin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1893_XYLFT
Sequence: MNLHFYSTLRFTVALAAGLLFGFGLALSEMINPIRVLSFLNVASGHWNPSLLFVLGSALAVAFPGMALQRRLKRPLLDECFHLPSKKVIDRRIVFGSAIFGTGWGLTGLCPGPAIASLSTGLGSVLLFVAAMAAGMIIHDRIVVRSLS
What are the official names of this protein?
UPF0394 membrane protein PD_1893.
What is the protein family that this protein belongs to?
Belongs to the UPF0394 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL33_THIDA
Sequence: MAKGGREKIKLESTAGTGHFYTTTKNKKTMPEKMEISKFDPKARKHVMYKETKLK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: ADA17_MOUSE
Sequence: MRRRLLILTTLVPFVLAPRPPEEAGSGSHPRLEKLDSLLSDYDILSLANIQQHSIRKRDLQSATHLETLLTFSALKRHFKLYLTSSTERFSQNLRVVVVDGKEESEYSVKWQNFFSGHVVGEPDSRVLAHIGDDDVTVRINTDGAEYNVEPLWRFVNDTKDKRMLVYKSEDIKDFSRLQSPKVCGYLNADSEELLPKGLIDREPSEEFVRRVKRRAEPNPLKNTCKLLVVADHRFYKYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGVQIEQIRILKSPQEVKPGERHFNMAKSFPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYNPTVKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKPGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGDAEDDTVCLDLGKCKAGKCIPFCKREQELESCACVDTDNSCKVCCRNLSGPCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHHSNIEMLSSMDSASVRIIKPFPAPQTPGRLQALQPAAMMPPVPAAPKLDHQRMDTIQEDPSTDSHADDDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQSRVDSKETEC
What is the function of this protein?
Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form.  Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface.  Plays a role in the proteolytic processing of ACE2 (By similarity).  Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein (PubMed:10799547, PubMed:11108241).  Acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membrane-associated intermediate fragment called notch extracellular truncation (NEXT) (PubMed:10882063).  Plays a role in hemostasis through shedding of GP1BA, the platelet glycoprotein Ib alpha chain (PubMed:12907434).  Mediates the proteolytic cleavage of LAG3, leading to release the secreted form of LAG3 (PubMed:17245433).  Mediates the proteolytic cleavage of IL6R, leading to the release of secreted form of IL6R (By similarity).  Mediates the proteolytic cleavage and shedding of FCGR3A upon NK cell stimulation, a mechanism that allows for increased NK cell motility and detachment from opsonized target cells.
What are the official names of this protein?
Disintegrin and metalloproteinase domain-containing protein 17, ADAM 17, TNF-alpha convertase, TNF-alpha-converting enzyme.
What are the subcellular locations of this protein?
[Isoform Long]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform Short]: Secreted.
Protein: RS2_METEP
Sequence: MAVDFSMRQLLEAGAHFGHQSHRWNPKMQPYIFGTRNNIHIIDLAQTVPALHAALQAVSDTVARGGRVLFVGTKRQAADSIAEAAKRSAQYYVNSRWLGGMLTNWKTISGSIQRLRKVDETLEGGAVGLTKKERLMLTREKDKLEKALGGIKDMGGVPDLLFVIDTNKEQLAIKEAQRLGIPVAAIVDTNCNPDGISYIVPANDDAGRAIALYCDLIARAAIEGIGRGQGALGLDVGASEEPTAEELPPANDDVAVSVASDAIAPADVAALAESTEHFEQLAAPRGAPDDLTKLNGVGPQLVQKLNDAGVWHYWQIAAMQPEDVAKLDADLKLNGRFARDGWVEQSRAFVEASAA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: YD1J_SCHPO
Sequence: MSKIFFRLNLVRNSLWRRAASFTSYSELKSLTPYEILELPRTCTANDIKRKYIELVKKHHPDKMKNASQLAPTESPPEINKHNEEYFRLLLAANALLSDKRRREEYDRFGIHWNQPSHPTHPSPQNWSQARYPTYSRSRRSAGMGSWEEYYYNSYDYMNDQNASNKNRKFDDEGMLVFAGILSILVIINIYSNYRNGKFYREARSAAIGRAEDNFDYYSTGMADLSKDDRISRFLILREQSKQIPTQQKPSSLPPPERALPAPTMPTPSS
What are the official names of this protein?
Uncharacterized J domain-containing protein C4G9.19.
Protein: KUP_PSEAB
Sequence: MSDAATRAEETSEGHSSSAIGLMVGAVGVCYGDIGTSPLYTLKEVFIGGYGVQANHDGVLGVLSLIFWSLVWVVSIKYVIFVLRADNQGEGGVMALSALARRAAAPFGRLQTFVVVAGLIGAALFYGDSMITPAISVLSAVEGLEIAFDGLEHWTVPLALIVLIGLFLIQKHGTARIGILFGPVMVLWFGALAALGVYGVIQQPEVLQAMNPVWAVRFFGSHPGIGVAILGATVLALTGAEALYADMGHFGRKPIARAWFLLVLPALVLNYFGQGATILSNAEAARNPFYLLAPGWALLPMVALSTLATVIASQAVISGAFSLTRQAIQLGYVPRMTIQHTSSHEQGQIYIGGVNWALMVGVVLLVLGFESSASLAAAYGVAVTGTMLITTLLMGVVIWRLWKWPLWLGVPFFCVMLAVDSLFFAANLPKVIQGGAFPVIAGIVIFILMSTWKRGRQLLVERLDEGSLPLSVFISSMRVQPPHRVQGTAVFLTARTDAVPHALLHNLLHNQVLHEQVVLLTVVNEDSPRVPPDRRFEVEAYGDGFFRVILHFGFMEEPDIPAALRLCHLNELDFSPMRTTYFLSRETVIPSKRIGMARWREGLFAFLLKNANGNLRYFNLPLNRVIELGTQVEI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PURR_ECOLC
Sequence: MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYRR
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: RS10_METMJ
Sequence: MQKARIRLSGTDFEKIEMVCDRIKEIAERTGVNLAGPIPLPTKKLVVPTRKSPDGEGTATWDRWQMRVHKRLIDIDADERALRQLMRIQVPKDIGIEIVLES
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: THIQ_SALTY
Sequence: MLKLIDITWLYHHLPMRFTLAVERGEQVAILGPSGAGKSTLLNLIAGFLAPASGTLLIAGDDHTLTPPSRRPVSMLFQENNLFSHLNVQQNIGLGLNPGLTLNASQREKRDAIAHQMGIESLMTRLPGELSGGQRQRVALARCLVREQPVLLLDEPFSALDPALRQEMLTLVSDICRERQLTLLMVSHSVEDAARIAPRSIVVADGRIAWQGKTDELLSGQASASALLGIKSHIL
What is the function of this protein?
Part of the ABC transporter complex ThiBPQ involved in thiamine import (PubMed:9535878).  Responsible for energy coupling to the transport system (Probable).  Is also involved in thiamine pyrophosphate (TPP) transport (PubMed:9535878).
What are the official names of this protein?
Thiamine import ATP-binding protein ThiQ.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: REP1_YEAST
Sequence: MNGERLLACIKQCIMQHFQPMVYDESRCVIETTRGTFPVPDNYKKYKTLAFAFVGHVLNTDDTPVIEKELDWPDPALVYNTIVDRIINHPELSQFISVAFISQLKATIGEGLDINVKGTLNRRGKGIRRPKGVFFRYMESPFVNTKVTAFFSYLRDYNKIASEYHNNTKFILTFSCQAYWASGPNFSALKNVIRCSIIHEYISKFVEREQDKGHIGDQELPPEEDPSRELNNVQHEVNSLTEQDAEADEGLWGEIDSLCEKWQSEAEDQTEAEIIADRIIGNSQRMANLKIRRTKFKSVLYHILKELIQSQGTVKVYRGSSFSHDSIKISLHYEEQHITAVWVYLTVKFEEHWKPVDVEVEFRCKFKERKVDG
What is the function of this protein?
Part of the plasmid partitioning system, which ensures the equal distribution of replicated plasmid molecules to daughter cells.  The plasmids exist as well-organized plasmid foci within the nucleus that stay together throughout the cell-cycle and act as entity during segregation, effetively reducing copy number to one.  Plasmid partitioning requires the proteins REP1, REP2, and a cis-acting locus STB (REP3).  REP1-REP2 stably associate with CSE4-containing chromatin at STB during S-phase, marking the locus with a centromeric tag, and thereby probably catching mitotic spindle microtubules to the plasmid cluster and coupling plasmid segregation to chromosome segregation.  REP1-REP2 are required to recruit the cohesin complex to the STB locus for pairing of the replicated plasmid cluster, a prerequisite for successful plasmid segregation.  REP1-REP2 also negatively regulate expression of site-specific recombinase FLP and of RAF1.
What are the official names of this protein?
Partitioning protein REP1, R1, Protein Baker, Trans-acting factor B.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes with the STB locus of the 2-micron plasmid as foci in the nucleus near the spindle pole body. Is expelled from STB during a short interval between late G1 and early S phases.
Protein: PSR1_PHYSP
Sequence: MRLTYVLLVAVTTLLVSCDATKPSTEATAVSKRLLRFVEAADEEERRIDFSPEKLRKMLGDETYRLKKFGKWDSDGHTFDGLKHYLLLSDSSMVKLRNMYKAWLEQ
What is the function of this protein?
Secreted effector that possesses RNA silencing suppression activity by inhibiting the biogenesis of small RNAs in the host plant to promote enhanced susceptibility of host to the pathogen during infection (PubMed:23377181, PubMed:25902521, PubMed:29029698, PubMed:30963588).  Interferes with secondary siRNA production by associating with host nuclear protein PINP1 that acts as a regulator of the accumulation of both microRNAs and endogenous small interfering RNAs (PubMed:25902521).
What are the official names of this protein?
RxLR effector protein PSR1, Avirulence homolog protein 18, Suppressor of RNA silencing protein 1.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus. Note=The nuclear localization is required for this interaction.
Protein: R144A_HUMAN
Sequence: MTTTRYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHLQENEIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCPETMPITFLPGETSAAFKMEEDDAPIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFLLIHYDKGPCRNKLGHSRASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKCSKGDDDPLPT
What is the function of this protein?
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.  Mediates the ubiquitination and degradation of the DNA damage kinase PRKDC.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF144A, RING finger protein 144A, UbcM4-interacting protein 4, Ubiquitin-conjugating enzyme 7-interacting protein 4.
What is the protein family that this protein belongs to?
Belongs to the RBR family. RNF144 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Cytoplasmic vesicle membrane.