PharMolix/UniProtQA huggingface dataset:
Protein: PKNG_MYCTU
Sequence: MAKASETERSGPGTQPADAQTATSATVRPLSTQAVFRPDFGDEDNFPHPTLGPDTEPQDRMATTSRVRPPVRRLGGGLVEIPRAPDIDPLEALMTNPVVPESKRFCWNCGRPVGRSDSETKGASEGWCPYCGSPYSFLPQLNPGDIVAGQYEVKGCIAHGGLGWIYLALDRNVNGRPVVLKGLVHSGDAEAQAMAMAERQFLAEVVHPSIVQIFNFVEHTDRHGDPVGYIVMEYVGGQSLKRSKGQKLPVAEAIAYLLEILPALSYLHSIGLVYNDLKPENIMLTEEQLKLIDLGAVSRINSFGYLYGTPGFQAPEIVRTGPTVATDIYTVGRTLAALTLDLPTRNGRYVDGLPEDDPVLKTYDSYGRLLRRAIDPDPRQRFTTAEEMSAQLTGVLREVVAQDTGVPRPGLSTIFSPSRSTFGVDLLVAHTDVYLDGQVHAEKLTANEIVTALSVPLVDPTDVAASVLQATVLSQPVQTLDSLRAARHGALDADGVDFSESVELPLMEVRALLDLGDVAKATRKLDDLAERVGWRWRLVWYRAVAELLTGDYDSATKHFTEVLDTFPGELAPKLALAATAELAGNTDEHKFYQTVWSTNDGVISAAFGLARARSAEGDRVGAVRTLDEVPPTSRHFTTARLTSAVTLLSGRSTSEVTEEQIRDAARRVEALPPTEPRVLQIRALVLGGALDWLKDNKASTNHILGFPFTSHGLRLGVEASLRSLARVAPTQRHRYTLVDMANKVRPTSTF
What is the function of this protein?
Phosphorylates GarA.  May play a role in metabolic regulation via control of the phosphorylation status of GarA.  Plays a crucial role in the survival of mycobacteria within host macrophages, by blocking the intracellular degradation of mycobacteria in lysosomes.  Required for intrinsic antibiotic resistance.
What are the official names of this protein?
Serine/threonine-protein kinase PknG.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Also detected in growth media, suggesting that it can be translocated into host macrophages under specific conditions.
Protein: HPRT_METFV
Sequence: MLEKLKSTLEKSPVIKKGEYHYFVSPVTDGIPLTEPNLLMEIVDAIEKKFDLEDIDKIVCIEAMGIHLATALSIKTGIPFVVIRKKKYGLPGEVEIRQVTGYGESNLYVNGVNSGDKILVIDDVVSTGGTLISVINALKKISADIKYVIAVVEKGEGRKKVEKETGTKVNTLVKVDVIDGEVKIINNEV
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis.
What are the official names of this protein?
Hypoxanthine/guanine phosphoribosyltransferase, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_CAMC1
Sequence: MFIDSVKLTLSSGHGGAGAVSFRREKHVILGGPDGGDGGDGGDVYFVCDNNTHTLANYKGKRAMRASDGEAGMGRRMTGKKGESLELIVPPGTAVYDAQTNELLCDMVEEGQRTLFLKGGKGGLGNFHFKNSINQAPEYAQNGMPEESIEVRLELKLIADVGLVGFPNVGKSTLISAVSNAKPQIANYEFTTLTPKLGLVEVDQFSGFVMADIPGIIEGASDGRGLGVQFLKHIERNKILLFMIDSANYRSMSEQFSVLKEEVAKFSSVLASRDYAIAITRVDAAENLDENISEFMKSINLEPNQVGKFVYKQDLYSFDAKKPYFILPISSATNENIDELKFALLELLKKEL
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAL1_COCIM
Sequence: MADNFDRTADERIEFTTSKEVTVAPTFDDMHLKENLLRGIYAYGFESPSAIQSRAIVQICKGRDTIAQAQSGTGKTATFAISILQVIDTALRETQALVLSPTRELATQIQNVIMAVGDYMNVQCHACIGGTNVGDDIRKLDHGQHVVSGTPGRVADMIRRRHLRTRHIKMLVLDEADDLLARGFREQIYDVYRYLPPATQVVVLSATLPYDVLSMTTKFMTDPVRILVKRDELTLEGLKQYFIAVEKEEWKFDTLCDLYDTLTITQAVIFCNTRRKVDWLTDKMREANFTVSSMHGEMPQKERDSIMQDFRQGNSRVLISTDVWARGIDVQQVSLVINYDLPSNRENYIHRIGRSGRFGRKGVAINFVTSEDVRILRDIELYYSTQIDEMPMNVADLLG
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase FAL1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: HIS7_ZYMMO
Sequence: MQRIASIHRQTAETDVHIHLNLDGHGQYNVKTGIGFFDHMLDQLFRHSLIDCDVTVKGDLHIDPHHTIEDCALALGQAVQQALGDKAGITRFSHAYAPMDEALSRVAIDISGRPYLVWHSAFTQPRLGDLDTEMLEHWFLSFAQGAGLTLHVETLYGRNNHHIAESLFKALALALRQAVAIDAGKQGRIPSTKGSL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPAF2_IPOBA
Sequence: MGASRTGCYLLAVVLAAVMNAAIAGITSSFIRKVEKTVDMPLDSDVFRVPPGYNAPQQVHITQGDHVGKAMIVSWVTVDEPGSSKVVYWSENSQHKKVARGNIRTYTYFNYTSGYIHHCTIRNLEYNTKYYYEVGIGNTTRSFWFTTPPEVGPDVPYTFGLIGDLGQSFDSNRTLTHYERNPIKGQAVLFVGDLSYADNYPNHDNVRWDTWGRFVERSTAYQPWIWTAGNHEIDFAPEIGETKPFKPFTKRYHVPYKASGSTETFWYPIKRASAYIIVLSSYSAYGKYTPQYKWLEEELPKVNRTETPWLIVLMHSPWYNSYNYHYMEGETMRVMYEPWFVQHKVDLVFAGHVHAYERSERVSNVAYDIVNGKCTPVRDQSAPVYITIGDGGNLEGLATNMTDPQPEYSAFREASFGHATLDIKNRTHAYYSWHRNQDGYAVEADSMWVSNRFWHPVDDSTTTKL
What are the official names of this protein?
Purple acid phosphatase 2, Manganese(II) purple acid phosphatase 2.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.
What are the subcellular locations of this protein?
Secreted.
Protein: MDTG_ECOHS
Sequence: MSPCENDTPINWKRNLIVAWLGCFLTGAAFSLVMPFLPLYVEQLGVTGHSALNMWSGIVFSITFLFSAIASPFWGGLADRKGRKLMLLRSALGMGIVMVLMGLAQNIWQFLILRALLGLLGGFVPNANALIATQVPRNKSGWALGTLSTGGVSGALLGPMAGGLLADSYGLRPVFFITASVLILCFFVTLFCIREKFQPVSKKEMLHMREVVTSLKNPKLVLSLFVTTLIIQVATGSIAPILTLYVRELAGNVSNVAFISGMIASVPGVAALLLSAPRLGKLGDRIGPEKILITALIFSVLLLIPMSYVQTPLQLGILRFLLGAADGALLPAVQTLLVYNSSNQIAGRIFSYNQSFRDIGNVTGPLMGAAISANYGFRAVFLVTAGVVLFNAVYSWNSLRRRRIPQVSN
What is the function of this protein?
Confers resistance to fosfomycin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtG.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TPS1_CACFS
Sequence: MLSLNEIKFPVHWNLKPNPTSYVDHVYQEGLEFGVWRPDNKRDIVAHNNVVSLSKFFWPTVDFERLVMGGELMLWFFTFDDALDSGIYDDTKSLEIVRRMSAVFMEGTLCDDASGPEKVGYRLRQKCLEMCGKRRRDTFNRFITSCVQWIDSIIPFNKVKDGGSPHIELYSFLRKINIGAYPCVTLSEVFIDHYLDHSIWSSPRWVKMNENIAIVVTLINDLVSYEKEVNDNAGALNPLYFFQQQRKFNLPDSYNHMVNLIHFFVQDYLANEESFLKSLEPFENEKQQQDIYFMLDHLHFLISGSRMWSMQTPRYCSPTSPFIEMRPSFNQGNLMSKL
What is the function of this protein?
Terpene synthase that converts its substrate farnesyl diphosphate (FPP) into the sesquiterpene protoillud-7-ene.
What are the official names of this protein?
Terpene synthase 1.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: ATMP_ASPFL
Sequence: MDKLTATLAKVNYPSEVENGSMLLVVTLVILFLWFIIPSPVKRSNVSVPTVTLFNPYLPEFLSRVWFNSTAATVIYKGYRQHKDRAFRLLKPDGDIIVLSNKYVEELRQLPLTTLNALEAVFEDHVGKYTTILDDSHLHTEVIQKRLTPAINRLIPRIIDELDHGFAVEMPECEDKWVLIRPYEVFLRLVARAGARVFVGPDFCRTEKWLTASIDFTKNIFMTITLLRPIPSFLHPIIGPMLPSSRSLDTQLRYVQDELLGPEIVKRRQRQASGDPDYEKPDDFLQWMIDLAQNDKEGDPGNIAHRLLGLTSMAVVHTSAMSITHGLYDLITMAQWLEPLRQEIQEAMPDWKSSSYSSLVSLRRLDSFLKESQRFNPPGELSFHRVVKKDLVLSDGLRLPKGTHICMASGPIGMDTKYVSDPTTFDAFRYVDGDKAQSQFVHTSATSMHFGLGRYACPGRFFATFVLKAILSRFLVEYEFRFGPDQVGRPKNMLLGDKIVPNTSVDVYVRKRTGSRSTA
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the ATM2 gene cluster that mediates the biosynthesis of aflatrem, a tremorgenic mycotoxin with acute neurotoxic effects (PubMed:19801473, PubMed:2867895).  Synthesis of geranylgeranyl diphosphate (GGPP) by AtmG (a GGPP synthase) precedes condensation of GGPP with indole 3-glycerol phosphate, followed by epoxidation and cyclization by AtmM (a FAD-dependent monooxygenase) and AtmC (a prenyltransferase) to produce paspaline (PubMed:19801473).  AtmB is also essential for paspaline production, but its exact role has not been identified yet (PubMed:19801473).  AtmP, a cytochrome P450 monooxygenase, subsequently converts paspaline to 13-desoxypaxilline via PC-M6 by removal of the C-30 methyl group and oxidation at C-10 (PubMed:19801473).  AtmQ, a cytochrome P450 monooxygenase, then catalyzes the oxidation of 13-desoxypaxilline, first at C-7 to produce paspalicine and then at C-13 to form paspalinine (PubMed:19801473).  Finally, AtmD prenylates paspalinine to form aflatrem (PubMed:19801473).
What are the official names of this protein?
Cytochrome P450 monooxygenase AtmP, Aflatrem synthesis protein P.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ADT2_TACAC
Sequence: MTDAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIMDCVVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKAGDAREFKGLGDCLVKITKSDGIRGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPDPKNTHIFISWMIAQSVTAVAGLTSYPFDTVRRRMMMQSGRKGSDIMYTGTIDCWKKIARDEGSKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYT
What is the function of this protein?
ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (By similarity).  Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane (By similarity).  In addition to its ADP:ATP antiporter activity, also involved in mitochondrial uncoupling and mitochondrial permeability transition pore (mPTP) activity.  Plays a role in mitochondrial uncoupling by acting as a proton transporter: proton transport uncouples the proton flows via the electron transport chain and ATP synthase to reduce the efficiency of ATP production and cause mitochondrial thermogenesis.  Proton transporter activity is inhibited by ADP:ATP antiporter activity, suggesting that SLC25A5/ANT2 acts as a master regulator of mitochondrial energy output by maintaining a delicate balance between ATP production (ADP:ATP antiporter activity) and thermogenesis (proton transporter activity).  Proton transporter activity requires free fatty acids as cofactor, but does not transport it.  Probably mediates mitochondrial uncoupling in tissues that do not express UCP1.  Also plays a key role in mPTP opening, a non-specific pore that enables free passage of the mitochondrial membranes to solutes of up to 1. 5 kDa, and which contributes to cell death.  It is however unclear if SLC25A5/ANT2 constitutes a pore-forming component of mPTP or regulates it (By similarity).  Acts as a regulator of mitophagy independently of ADP:ATP antiporter activity: promotes mitophagy via interaction with TIMM44, leading to inhibit the presequence translocase TIMM23, thereby promoting stabilization of PINK1 (By similarity).  As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation (By similarity).
What are the official names of this protein?
ADP/ATP translocase 2, ADP,ATP carrier protein 2, Adenine nucleotide translocator 2, ANT 2, Solute carrier family 25 member 5.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Note=May localize to non-mitochondrial membranes.
Protein: F16PA_METPB
Sequence: MTKPNGSSLDDHLDAEVARDASLADTAATIRALAAAAIDVSETVGRGALAGDLAAQGEHNSDGDVQKALDVIAHKRFMQALEEAPVAQVASEEAEDVVSLKPGAPLAVAIDPLDGSSNIGVGMVVGTIFGIRPVTLGTDVNASFLTPGTTQTAAGFVVYGPATTFVVTLGNGTRIFTLDRAEKVFRLTHDALQIVPSANEYAINASNVRHWDGPVKSFIEDCLRGTEGPRDRDFNMRWTAALVADAQRVLIRGGVFLYPGDNRKGYAQGRLRLLYETAPIAFLIEQAGGAATDGQARIMERVATKIHERSPLVFGSTEEVECVAKYYDGRQPSAGRSPLFGQRGLMRS
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 159L_IIV6
Sequence: METETNFKIYNPLQQLEQGSIGGGSGSIPAGSVTGGAGGSIANATITNINIAAGTITGGSGGNIAAGTITGGSGGNIAPNTITAGELAAGAAAANINSGPAGAVNGSKVSKADNTNFGVIEFDPSGDLTQTAAGSGIAVLKTGAAAANINAGPAGAINSSQIAGGPFLSSSPGSVTGGPGGNIAAGTVTGGSGGDLAAGTVTGGAGGNIAAGTVTGGAGGNIAANTITAGELAAGAAAANINSGPAGAVNGSQISKADNTNFGVIEFDPSGDLKQTAAGSGIALVKQPAAGTSVTIAGFDSSGTFITSKVGSIVAAAVPNGTSLNFYNIMIRYPTVAPISLQISVAAVGAAPPPGPGFIGIGEQRWIVNTTINPNPPPPANPNPGTTPYLRTESRVTQNSVAVGTFSYLNVNNVATGAISALATPWDNSEQTVQGGAYERYEFYINDGVDASGYRVTAFYFSPSSFITIERLQGN
What are the official names of this protein?
Uncharacterized protein 159L.
Protein: YCX8_EUGLO
Sequence: MKKRRGPSEDENPRPEKLFTQKVFDYISRVILKYFKKTYKFIIYILKNLTLFKILYKCFPYIKNFILKIDKIFFHVLIKSINFIKYIPQLIHDKIFEFFWFILKIFQILIFVKIFKYVIKKFIIY
What are the official names of this protein?
Uncharacterized 15.7 kDa protein in rpl14-rpl12 intergenic region, ORF125b.
What are the subcellular locations of this protein?
Plastid.
Protein: RRP12_HUMAN
Sequence: MGRSGKLPSGVSAKLKRWKKGHSSDSNPAICRHRQAARSRFFSRPSGRSDLTVDAVKLHNELQSGSLRLGKSEAPETPMEEEAELVLTEKSSGTFLSGLSDCTNVTFSKVQRFWESNSAAHKEICAVLAAVTEVIRSQGGKETETEYFAALMTTMEAVESPESLAAVAYLLNLVLKRVPSPVLIKKFSDTSKAFMDIMSAQASSGSTSVLRWVLSCLATLLRKQDLEAWGYPVTLQVYHGLLSFTVHPKPKIRKAAQHGVCSVLKGSEFMFEKAPAHHPAAISTAKFCIQEIEKSGGSKEATTTLHMLTLLKDLLPCFPEGLVKSCSETLLRVMTLSHVLVTACAMQAFHSLFHARPGLSTLSAELNAQIITALYDYVPSENDLQPLLAWLKVMEKAHINLVRLQWDLGLGHLPRFFGTAVTCLLSPHSQVLTAATQSLKEILKECVAPHMADIGSVTSSASGPAQSVAKMFRAVEEGLTYKFHAAWSSVLQLLCVFFEACGRQAHPVMRKCLQSLCDLRLSPHFPHTAALDQAVGAAVTSMGPEVVLQAVPLEIDGSEETLDFPRSWLLPVIRDHVQETRLGFFTTYFLPLANTLKSKAMDLAQAGSTVESKIYDTLQWQMWTLLPGFCTRPTDVAISFKGLARTLGMAISERPDLRVTVCQALRTLITKGCQAEADRAEVSRFAKNFLPILFNLYGQPVAAGDTPAPRRAVLETIRTYLTITDTQLVNSLLEKASEKVLDPASSDFTRLSVLDLVVALAPCADEAAISKLYSTIRPYLESKAHGVQKKAYRVLEEVCASPQGPGALFVQSHLEDLKKTLLDSLRSTSSPAKRPRLKCLLHIVRKLSAEHKEFITALIPEVILCTKEVSVGARKNAFALLVEMGHAFLRFGSNQEEALQCYLVLIYPGLVGAVTMVSCSILALTHLLFEFKGLMGTSTVEQLLENVCLLLASRTRDVVKSALGFIKVAVTVMDVAHLAKHVQLVMEAIGKLSDDMRRHFRMKLRNLFTKFIRKFGFELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPPQYQAGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKGRPDPYAYIPLNRSKLNRRKKMKLQGQFKGLVKAARRGSQVGHKNRRKDRRP
What are the official names of this protein?
RRP12-like protein.
What is the protein family that this protein belongs to?
Belongs to the RRP12 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus membrane; Single-pass membrane protein.
Protein: OR65B_DROME
Sequence: MDIQRFLKFYKVGWKTYRDPLMEASHSSIYYWREQMKAMALFTTTEERLLPYRSKWHTLVYIQMVIFFASMSFGLTESMGDHVQMGRDLAFILGAFFIIFKTYYFCWYGDELDQVISDLDALHPWAQKGPNPVEYQTGKRWYFVMAFFLATSWSFFLCILLLLLITSPMWVHQQNLPFHAAFPFQWHEKSLHPISHAIIYLFQSYFAVYCLTWLLCIEGLSICIYAEITFGIEVLCLELRQIHRHNYGLQELRMETNRLVKLHQKIVEILDRTNDVFHGTLIMQMGVNFSLVSLSVLEAVEARKDPKVVAQFAVLMLLALGHLSMWSYCGDQLSQKSLQISEAAYEAYDPTKGSKDVYRDLCVIIRRGQDPLIMRASPFPSFNLINYSAILNQCYGILTFLLKTLD
What is the function of this protein?
Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates.  The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration.  May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability (By similarity).
What are the official names of this protein?
Putative odorant receptor 65b.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family. Or49a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CHS1_SCHPO
Sequence: MRRWFKKTLPRPPDEEESAGLTNKDIVETNHLYPTITNLSLNSDTSSILFDKNKKPLKPKIIIPDKEFDLDYYLKDETESIQSPFEGFTAQPNFSNFNKQGNTMNREANFQRTNEKIQRNKSIKRVKLFHGNLILDCPIPKKLLVTLPQQTEREFAYMRYSAATCDPQDFSKSLFTLRQPLFFQPRKTEICIAITMYNEDEVLFARTMHSVMKNISHLCTRKNSQVWGKDAWKKVVVCIISDGRTKIHPRTLAYLAAIGVYQDGIAKNQVNDKEVKAHIYEYTTQLSIDPNLKFKGSDRGIVPVQMIFCLKEKNQKKLNSHLWFFQAFCPILKPEVCILLDAGTRPGDQSIYHLWKSFDLNPQVAGACGEIVVMKGKLGSGLINPLVATQNFEYKMSNILDKPVESVFGFISVLPGAFSAYRFEALQNDSQGNGPLASYFKGELQNTGKSGIFEANMYLAEDRILCFELVSKKNEAWILHYVKSAYADTDVPDRIPEFVLQRRRWLNGSFFAAAYAICHYYRFFRTSHTISRKFMLSIEFIYQLATIVFGWFNIGNFFIIFYILTSSLASTSANFLPGEILFRIAIWIYASLLVTCFVLALGNRPHGSPNFYLSMVIMYSILMGYLLFCSGWIAYRAISDAIHNASSTSSSYTSALLNSNVFINIVISLSSTYGMYLVVSIISFDPWHMFTSFVQYIFLSIMYTNVLNVYAFCNTHDVSWGTKGDHFTNNDLGVARLLQKGADVEIAIPTNQSDIDAKYEDAVKLLASPSLEFNSPIINHGEQEDFYKNFRTYVVLTWILSNLFLVGIVLSIPKINGISISNNETSAYLSFLLWSVVAFSVFRFIGCIFYLFIRLCTGE
What is the function of this protein?
Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.
What are the official names of this protein?
Chitin synthase 1, Chitin-UDP acetyl-glucosaminyl transferase 1.
What is the protein family that this protein belongs to?
Belongs to the chitin synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TDIE_EMENI
Sequence: MVNRPYANMNDLANAVAESVQKYLDNSGQARNGLFQKTNNGERDIETERLALQHQLFHLTLDGKLQLSPLPSPVQSVLDIATGDSTWVHAFAEQNPSAYIVANDPSPTSKIPLGLSVIPDASDANEPWTYTRQFDFVHCRQHHRRLDEPRLFKQAFSSLTPGGWLEMQELSNPVTSDDGTLSENNPLSQWGRLLIEASKKMNRPVDNPAKYETWMREAGFVNCHTVAYNWPTNPWPADEKGKTLGLWNLYNVLQRFEEFSVALLVKVLGWEMDDAKTFLGNVKEELMNEGVHGYWPVYVVYGQKPAAPGSDVITDSE
What is the function of this protein?
Probable methyltransferase; part of the gene cluster that mediates the biosynthesis of terrequinone A, an antitumor agent (PubMed:17704773, PubMed:16426969, PubMed:17291795, PubMed:22083274).  The first step in the biosynthetic pathway for terrequinone A is formation of indole pyruvic acid (IPA) from L-tryptophan by the aminotransferase tdiD (PubMed:17704773).  The nonribosomal peptide synthase tdiA then immediately converts unstable IPA to didemethylasterriquinone D (DDAQ D), via condensation of 2 IPA molecules (PubMed:17704773).  The symmetric connectivity of the 2 IPA molecules is thought to arise by head-to-tail dual Claisen condensations facilitated by the TE domain (PubMed:17704773).  TdiB then catalyzes reverse prenylation by transferring dimethylallyl diphosphate to carbon atom 2' of DDAQ D, to yield asterriquinone C-1 (PubMed:18029206).  Finally, tdiC and tdiE enzymes robustly convert asterriquinone C-1 to terrequinone A via a transformation involving regular prenylation at carbon atom 5, which requires elimination of the hydroxy group on C-5 (PubMed:17704773, PubMed:18029206).
What are the official names of this protein?
Probable methyltransferase tdiE, Terrequinone biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. LaeA methyltransferase family.
Protein: SYL_RUEPO
Sequence: MSRYSATEIEAKWQEAWDKAGIFRAARTADKPKYYVLEMFPYPSGRIHIGHVRNYTMGDVIARYKLSNGFNVLHPMGFDAFGMPAENAAMASGGHPKDWTYKNIETMVAQMKPLGFGLDWSRMFATCDPEYYGQQQALFLDFLEKGLVYRKNAVVNWDPVDMTVLANEQVEDGRGWRSGALVERRELTQWFFKISDMSGELLDALDTLDDWPAKVKLMQANWIGKSRGLQFSWALTEPAHGIEALDVYTTRPDTLMGASFLGISPDHPLTKALEAENPDLAAKVAEMRKGGTTEEAIEKAEKLGADTGLRVRHPLNPDWELPVWVANFILMDYGTGAIFACPAHDQRDLDFCRKYDLPVIDTFVALDDPKPIATEAFVPLKTEKVKWIDHFAGLDVATGQEAIDTTIDWMEAKGLGTGVTKFRLRDWGLSRQRYWGCPIPVVHCDACGVVPEKKENLPIRLPDDVTFDVPGNPLDRHPTWRDCACPSCGKPARRETDTMDTFVDSSWYFARFTAPRAETPTDMAEAEYWMNVDQYIGGIEHAILHLLYSRFFARAMHICGHLPEKSKEPFNALFTQGMVTHAIYKTTGADDRPVYHYPEAVRLEGGKGYLEDGTEVEIIPSAKMSKSKNNVVDPVAIIDRFGADTARWFVLSDSPPERDVEWTDAGAEAAHKHLNRVWNLCDRIAAMDSAAPGEGDDDLLREMHKCIRDVTNGIESFGFNASIAKLYAFTNTLAKSKAGAAAQKQAIMTLAQLMSPMTPHLAEDIWAHQGGEGLIAAAPWPVADEAMLVDALVTLPVQINGKRRAEISVPADMDKTQVEKLALSTDAVQKALDGAAPKKVIVVPGRIVNVVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_MYCTA
Sequence: MTTTAEKTDRPGKPGSSDTSGRVVRVTGPVVDVEFPRGSIPELFNALHAEITFESLAKTLTLEVAQHLGDNLVRTISLQPTDGLVRGVEVIDTGRSISVPVGEGVKGHVFNALGDCLDEPGYGEKFEHWSIHRKPPAFEELEPRTEMLETGLKVVDLLTPYVRGGKIALFGGAGVGKTVLIQEMINRIARNFGGTSVFAGVGERTREGNDLWVELAEANVLKDTALVFGQMDEPPGTRMRVALSALTMAEWFRDEQGQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGELQERITSTRGRSITSMQAVYVPADDYTDPAPATTFAHLDATTELSRAVFSKGIFPAVDPLASSSTILDPSVVGDEHYRVAQEVIRILQRYKDLQDIIAILGIDELSEEDKQLVNRARRIERFLSQNMMAAEQFTGQPGSTVPVKETIEAFDRLCKGDFDHVPEQAFFLIGGLDDLAKKAESLGAKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DSVD_DESVH
Sequence: MEEAKQKVVDFLNSKSGSKSKFYFNDFTDLFPDMKQREVKKILTALVNDEVLEYWSSGSTTMYGLKGAGKQAAAEHED
What is the function of this protein?
May play an essential role in dissimilatory sulfite reduction.
What are the official names of this protein?
Protein DsvD.
What is the protein family that this protein belongs to?
To A.fulgidus DsrD.
Protein: PHEB_AGACH
Sequence: MLDAFSRVISNADAKAAYVGGSDLQALRTFISDGNKRLDAVNYIVSNSSCIVSDAISGMICENPGLITPGGNCYTNRRMAACLRDGEIILRYISYALLAGDSSVLEDRCLNGLKETYIALGVPTNSTVRAVSIMKAAVGAFISNTASQRKGEVIEGDCSALAAEIASYCDRISAAVS
What is the function of this protein?
Light-harvesting photosynthetic tetrapyrrole chromophore-protein from the phycobiliprotein complex.
What are the official names of this protein?
R-phycoerythrin beta chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side. Note=Forms the periphery of the phycobilisome rod.
Protein: MYO1C_CHICK
Sequence: MESALTARDRVGVQDFVLLENFTSEAAFIENLRKRFKENLIYTYIGSVLVSVNPYKELEIYSKQNMERYRGVSFYEVSPHLYAIADNSYRSLRTERKDQCILISGESGAGKTEATKKILQYYAVTCPASQQVETVKDRLLQSNPVLEAFGNTKTLRNDNSSRFGKYMDVQFDYRGAPVGGHILNYLLEKSRVVHQNHGERNFHIFYQLLEGGEEDLLRRLGLEKNPQQYHYLVKGHCARVSSINDKNDWKVVRRALSIISFNDNEVEDLLSIVASVLHLGNVQFAADEQGNAQVTTENQIKYLARLLAVEGSVLRDALIHKKIIAKGEELISPLNLEQAAYARDALAKAIYGRTFSWLVNKVNKSLAYKEGEFPGWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYESEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGDATDTTFLEKLEETVKNHPHFLTHKLADQKTRKSLGREEFRLLHYAGEVTYSVAGFLDKNNDLLFRNLKETMCNSENPIINQCFDRTELTDKKRPETAATQFKNSLSKLMEILMSKEPSYIRCIKPNDAKQADRFDEVLIRHQVKYLGLMENLRVRRAGFAYRRKYEVFLQRYKSLCPETWPTWDGRPHDGVAVLVKHLGYKQEEYKMGRTKIFIRFPKTLFATEDALEVRKQSLATKMQATWRGFYRRKKFLHMKHSAIAIQSWWRGTLGRRKAAKRKWAVQTIRRFIKGFIYRNHPRCPENEYFLDYIRFSFLMNLKRNLPKNVLDKSWPTPPPSLCEASQLLRQLCMQNMVWTYCKRISPEWKQQLEQKVIASEIFKGKKDNYPQSVPRLFINTRLGNEEINAKVLQALENEAIKYAVPVIKYDRKGYKARSRQLLLTQNAVIIVEDSKIKQRIDYANLTGISVSSLSDNLFVLHVHCEDNKQKGDVVLQSDHVIETLTKTAMRADKVNNININQGSIKFTVGQGKEGIIDFISGSELLIAKAKNGHLTVVAPRLNSR
What is the function of this protein?
Myosins are actin-based motor molecules with ATPase activity.  Unconventional myosins serve in intracellular movements.  Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity).
What are the official names of this protein?
Unconventional myosin-Ic, Myosin I beta, MMI-beta, MMIb.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, ruffle. Cytoplasmic vesicle. Cell projection, stereocilium membrane.