PharMolix/UniProtQA huggingface dataset:
Protein: TBX1_XENTR
Sequence: MISAISSPWLTQLSHFCDVAAFTANSLSSLNASGGYHLSPSPGDPYSQHEPHYEPCSASQHSYSFGHACPEPESGASSSSCASSTPGSGSTGSSGSSKAPVKKNPKVANITVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKIFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGSLPLMNAFARSRNPVSSPPQNGSDKDGDGRREYERDTSGTPLHGDAAHQQLMSRVLSPSLPVPGGLVPLSTGRPSPPHELRLDPHSQGSEPLHHHPYKYPTSYDHYLGAKTRPAPYPLPSIRGHGYHHHPMNPAAANMYSGAGAPGSYEYGPR
What is the function of this protein?
Probable transcriptional regulator involved in developmental processes (By similarity).  Binds to the palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence (By similarity).  Induces pre-placodal ectoderm (PPE) gene expression in regions where RIPPLY3 is absent.  Plays a role in the formation of the anteroposterior (AP) axis during embryonic development; required to establish the posterolateral border of the pre-placodal ectoderm (PPE) acting downstream of the retinoic acid receptor (RAR) signaling (By similarity).
What are the official names of this protein?
T-box transcription factor TBX1, T-box protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: GERPA_BACCE
Sequence: MPAMVGHIRIVNIGSSGIFHIGDVFAIRPISYSRAFAGAGSFNVGDNVSVYNYQSATTVNDSDVVDQAIIGST
What is the function of this protein?
Required for the formation of functionally normal spores.  Could be involved in the establishment of normal spore coat structure and/or permeability, which allows the access of germinants to their receptor.
What are the official names of this protein?
Probable spore germination protein GerPA.
What is the protein family that this protein belongs to?
Belongs to the GerPA/GerPF family.
Protein: EFP_POLNS
Sequence: MKTAQELRVGNVVMIGTDAQVVLKAEYSRSGRNSSVVKMKFKNLLTGAPNEGVYKADDKFDVVILDKKECTYSYFADPMYVFMDGDYNQYEVEAEFMGDALNYLEESMPCEVVFYEGKALSVAMPNSLVREIIYTEPAVKGDTSSGKVLKNAKLATGYELQVPLFCNTGDKIEIDTRTGEYRSRAN
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_POLNA
Sequence: MDKLRIKGGKSLAGSVDISGAKNAALPELCAALLTAETVTLQNVPGLQDVATMLKLIRNMGVEAERSAHAPGTVILNAGPLSSPEAPYELVKTMRASVLALGPLLARFGEATVSLPGGCAIGSRPVDQHIKGLQAMGADIIVEHGYMLARLPKGQTRLKGAAITTDMVTVTGTENFLMAATLAEGETILENAAQEPEIGDLAEMLIKMGAKIEGHGSRRIRIQGVERLHGCTHQVVADRIETGTFLCAVAAAGGDVVLNHGRADHLEVVIEKLREAGATVTAGEGFIRIQASGRMKAQSFRTTEYPGFPTDMQAQFMALNAIAQGTSTVTETIFENRFMHVNEMVRLGAKIQIEGKVCVINGVEQLSGATVMATDLRASASLVIAGLVASGETFVERIYHLDRGYDQMEAKLRGIGADIERMKA
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SKP1A_DICDI
Sequence: MSLVKLESSDEKVFEIEKEIACMSVTIKNMIEDIGESDSPIPLPNVTSTILEKVLDYCRHHHQHPSPQGDDKKDEKRLDDIPPYDRDFCKVDQPTLFELILAANYLDIKPLLDVTCKTVANMIRGKTPEEIRKIFNIKNDFTPEEEEQIRKENEWCEDKGGN
What are the official names of this protein?
SCF ubiquitin ligase complex protein SKP1a, Glycoprotein FP21 isoform A.
What is the protein family that this protein belongs to?
Belongs to the SKP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TX2_CERMR
Sequence: DCLGWFKSCDPKNDKCCKNYTCSRRDRWCKYYL
What is the function of this protein?
Inhibits several voltage-gated sodium channels and only one voltage-gated calcium channel (Cav2. 2/CACNA1B (IC(50)=1. 1 uM) and Nav1. 2/SCN2A (IC(50)=3. 7-80 nM), Nav1. 3/SCN3A (IC(50)=88-5570 nM), Nav1. 1/SCN1A (IC(50)=170-407 nM), Nav1. 7/SCN9A (IC(50)=95. 5-230 nM), Nav1. 6/SCN6A (IC(50)=49. 9-3990 nM), Nav1. 4/SCN4A (IC(50)=113-400 nM or >10 uM), Nav1. 5/SCN5A (IC(50)=1524-1634 nM or >10 uM)) (PubMed:16267209, PubMed:28880874, PubMed:29703751).  The toxin acts by shifting the voltage dependence of channel activation to more depolarized potentials and by blocking the inward component of the sodium current (PubMed:16267209).  It shows moderate affinity for lipid bilayers without cholesterol and high affinity for lipid bilayers containing cholesterol (PubMed:29703751).  In vivo, this toxin causes general ataxia, lack of response to stimuli, and semiparalysis (PubMed:16267209).  After a few minutes, the mice are unable to stand, and breathing is reduced in rhythm and intensity (PubMed:16267209).  Symptoms gradually increase with progressive slowing of breathing and flaccid paralysis; death occurred within 10 to 20 minutes post injection (PubMed:16267209).  Animals remain totally flaccid, and no symptoms of excitatory neurotoxicity are observed (PubMed:16267209).
What are the official names of this protein?
Beta-theraphotoxin-Cm1b, Beta-TRTX-Cm1b, CcoTx-II, Ceratotoxin-2, CcoTx2.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 04 (CcoTx1) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HACD3_CHICK
Sequence: MADCSLRPHVHWAQRHRELYLRVELSDVKNPDVSIADNVLRFRAQGHGAKGDNIYEFQIEFLEPVEPKPVCRVTQRQLNITVQKKESSWWERLTKQEKRPLFLAPDFDRWLDESDAEMELKEKEEEKINKMKIESRVPKDPFKHLKKGYLIMYNLVQFLGFSWIFVNMTVRLFILGKDSFYDTFHTIADMMYFCQTLALMEILNSLIGLVRSPLIPAVIQVFGRNFILFVVLGSLEEMQSKAVVFFLFYFWSIIELFRYPYYMLSCMGIEWKPLTWLRYTSWIPLYPLGGLAEAVCLIQSIPIFSETGKFSLGLPNPLNVTIQFSFLLQMYLIALFLGLFVNFRYLYKQRKQHLGPKKRKMK
What is the function of this protein?
Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle.  This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle.  This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation.  Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.  Involved in Rac1-signaling pathways leading to the modulation of gene expression.
What are the official names of this protein?
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase, 3-hydroxyacyl-CoA dehydratase, HACD, Protein-tyrosine phosphatase-like A domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the very long-chain fatty acids dehydratase HACD family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: GCSH_AGRVS
Sequence: MLKFTSEHEWLQIEGDIATVGITAHAAEQLGDLVFVELPEVGATFAKDGQAATVESVKAASDVYCPLDGEVTEINQAIVDDPSLVNSDPRGAGWFFKLKLANPADAEGLLNEAAYNELIA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: Y3265_CUPPJ
Sequence: MIPSFKSTTQARGALAEDRALAHLQRHGLQPVVRNYRCKGGEIDLVMRAPDGTLVFIEVRQRSASAFGGAAASVTPAKQRRVVLAALHYLSTLAQQPPCRFDVVALAPGRLEWLQHAFDLDTAGEAG
What are the official names of this protein?
UPF0102 protein Reut_A3265.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: STAR_RAT
Sequence: MLLATFKLCAGSSYRHMRNMKGLRHQAVLAIGQELNRRALGDPSPGWMGQVRRRSSLLGSQLEATLYSDQELSYIQQGEEAMQKALGILNNQEGWKKESQQENGDEVLSKVVPGVGKVFRLEVLLDQPMDRLYEELVDRMEAMGEWNPNVKEIKVLKKIGKDTVITHELAAAAAGNLVGPRDFVSVRCTKRRGSTCVLAGMATHFGEMPEQSGVIRAEHGPTCMVLHPLAGSPSKTKLTWLLSIDLKGWLPKTIINQVLSQTQIEFASHLRKRLESSPASEAQC
What is the function of this protein?
Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone.  Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone (By similarity).
What are the official names of this protein?
Steroidogenic acute regulatory protein, mitochondrial, StAR, START domain-containing protein 1, StARD1.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LUXS_NEIMB
Sequence: MPLLDSFKVDHTRMHAPAVRVAKTMTTPKGDTITVFDLRFCVPNKEILPGKGIHTLEHLFAGFMRDHLNGNGVEIIDISPMGCRTGFYMSLIGTPSEQQVADAWLASMQDVLNVKDQSKIPELNEYQCGTYQMHSLAEAQQIAQNVLARKVAVNKNEELTLDEGLLNA
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: PDXA2_RHIME
Sequence: MSKIIGITMGDPCGVGPEITVRSLAEMSAADREATRIYGNLATLEAAREALGLSVDLQPYVVDLTVEGAPLPWGSLSAVAGDAAFRFIERAVRDAEAGNIGCIVTAPINKEALNMAGHHYDGHTGMLRSLTGSSAAYMLLASERLKVIHVSTHVSLKEAIGRATTERVLATIRAGNAHLKRIGYEHPRIAVAGINPHCGENGLFGTEDDDQIGPAVAAAREEGIDVQGPISADTVFHRAYSGGFDLVVAQYHDQGHIPIKLVAFDTAVNVSVDLPIDRTSVDHGTAFDIAGKGIANHGNLNSAIAYARKLVAGQASRKAAS
What is the function of this protein?
Catalyzes the NAD-dependent oxidation and subsequent decarboxylation of D-threonate 4-phosphate to produce dihydroxyacetone phosphate (DHAP).
What are the official names of this protein?
Putative D-threonate 4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family. PdxA2 subfamily.
Protein: RS2_RALSO
Sequence: MSVTMREMLEAGVHFGHQTRFWNPKMAPFIFGHRNKIHIINLEKTLPMYLDALKYVRQLAANRGTILFVGTKRQSREILAEEAARAGMPYVDSRWLGGMLTNFKTVKISIKRLKDMEAAKEAGALESMSKKEALMFEREMEKLEKSIGGIKDMGGIPDAIFVVDVGYHKIAVTEAAKLGIPVIGVVDTNHSPEGIDYVIPGNDDSSKAVALYVRGVADAILEGRANAVQEVVEAARGGDDFVEVQEG
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: CCSA_ARAHI
Sequence: MIFSILEHILTHISFSVVSIVLTIYFLTFLVNLDEIIGFFDSSDKGIVITFFGITGLLFTRWIYSGHFPLSNLYESLIFLSWAFSIIHMISYFNKKQKNHLNAITAPSAIFIQGFATSGLLNKIPESAILVPALQSQWLMMHVSMMILGYGALLCGSLLSIALLVITFRKTGPTFWNKNIKKNNLLTEFFYFDVLYYINERNSILLQQNSNFSFSRNYYRYQLIEQLDYWSFRIISLGFIFLTVGILSGAVWANETWGSYWNWDPKETWAFITWTIFAIFLHIKTNRNVRGINSAIVASTGFLLIWICYFGVNLLGIGLHSYGSFTSN
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: LACD_LISMH
Sequence: MVQITKGKFDGLQRLSNEKGVIAALAIDQRGSLKKMIQQAKGTENKKDVEDFKQLVSEELTPYASAILLDLEYGTPAIKARHEGSGLLTSYEKTGYDATTPGKLPDLIEDLSALRIKENGGDAVKILVYYDPDEPAEINEIKYAFLERIGAECRAVDIPFFLEPITYDAKVTDSGSLEYAKLKPAKVKASIKEFSKPRYGVDVLKLEVPVNFKYVEGFAEGEVAYTQDEAARHFEECSDLSPLPFIYLSAGVTSEMFHKTIQFANQHNVQYSGVLCGRATWADGIEVYGKQGDDALREWLRTQGKENITSLDKLLDEGAVPWWTKYGSFEDVHVVEKQ
What are the official names of this protein?
Tagatose 1,6-diphosphate aldolase, D-tagatose-1,6-bisphosphate aldolase, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase LacD family.
Protein: MTNN_LISMO
Sequence: MTIGIIGAMEEEVELLKNSMSSVEEIVIGGAKFYIGEIASKEVVLLESGIGKVNAALGTTLMADRFKPEVIINTGSAGGMAEGLAVGDVIISDRLAYGDVDVTEFGYTYGQVPRMPAFYQGDAVLLKKAETIYREYFATSENKAVYGLVVTNDSFIMRPDQHEIIRTFFPDVKAVEMEAAAIAQVAYQFDIPFLIIRAISDLANQEATISFDEFIHLAAKQSATCIIELLKTI
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: IF4A3_ORYSJ
Sequence: MAGMAPEGSQFDAKHYDSKMQELLHQGDNEEFFTSYDEVFESFDDMGLQENLLRGIYAYGFEKPSAIQQRGIVPFCKGLDVIQQAQSGTGKTATFCSGILQQLDYGLVECQSLVLAPTRELAQQIEKVMRALGDYLGVKVHACVGGTSVREDQRILASGVHVVVGTPGRVFDMLRRQSLRPDHIKMFVLDEADEMLSRGFKDQIYDIFQLLPPKIQVGVFSATMPPEALEITRKFMNKPVRILVKRDELTLEGIKQFYVNVEKEDWKLDTLCDLYETLAITQSVIFVNTRRKVDWLTDKMRSRDHTVSATHGDMDQNTRDIIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTQPENYLHRIGRSGRFGRKGVAINFVTRDDERMLFDIQRFYNVTIEELPANVADLL
What is the function of this protein?
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.  In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
What are the official names of this protein?
Eukaryotic initiation factor 4A-3, eIF-4A-3, ATP-dependent RNA helicase eIF4A-3, DEAD-box ATP-dependent RNA helicase 23, eIF4A-2.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. eIF4A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes to the nucleus when interacting with DRM2.
Protein: RR3_ARATH
Sequence: MGQKINPLGFRLGTTQSHHSLWFAQPKKYSEGLEEDKKIRDCIKNYVQKNIRISSGMEGIARIEIQKRIDLIQIIIYMGFPKLLIEDKPRRVEELQMNVQKELNCVNRKLNIAITRISNPYGDPNILAEFIAGQLKNRVSFRKAMKKAIELTEQANTKGIQVQIAGRIDGKEIARVEWIREGRVPLQTIEAKIDYCSYTVRTIYGVLGIKIWIFVDEE
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS16_DICTD
Sequence: MVKIRLTRVGAKNKPAYRIVAMDSREPRDGKHLEILGFYDPKTDPATIQLKEERILYWLSQGAQPTDTVLSILKRYGVWDKFLAMKKSAKSSA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RIBA_ACIBY
Sequence: MPIEFIATSKLPTAFGEFNISVFQDPVTGEEHVALSKGLENPPTGPVLVRVHSECLTGDAFASLKCDCGPQLQATQKLINEAGQGVILYLRQEGRGIGLTNKIRAYALQDQGHDTVDANLLLNLPADARRYDMCSIMLDHLKVKEVKLITNNPLKIQALKDQGINVVDRVPLTVGRNPFNEQYLKTKRERMDHLYQKDDF
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: YBEY_NITMU
Sequence: MKERSSSPGTPDSGRRARPKPAKLKMTVQYATSTREPLPSRALLRKWVKAALAHDAEIALRIVDEEEGHRLNRDFRNKDYATNVLTFVYRDGQIHPDSPLGEKRGAYPLTGDIVLCAPVVENEAGQQQKDLMAHYAHLTVHGVLHLQGYDHQEDEDAKNMEETETRILAWLGYEDPYAGYQLAEAVDCG
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYSC_PONPY
Sequence: MKALIILGLVLLSVTVQSKVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTRATNYNPGDRSTDYGIFQINSRYWCNDGKTPGAVNACHLSCSALLQDNIADAVACAKRVVRDPQGIRAWVAWRNRCQNRDVRQYVQGCGV
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
What are the official names of this protein?
Lysozyme C, 1,4-beta-N-acetylmuramidase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HLDD_CUPTR
Sequence: MTIIVTGAAGFIGSNLVKGLNERGETNVIAVDNLTRADKFHNLVDCEISDYLDKQDFLARFARGEFGKVRAVFHEGACSDTMETDGRYMMENNYRYTLSLMESCLEQGTQFLYASSAATYGASQVFREDREFERPLNVYGYSKFLFDQIVRRRLPSALSQIVGFRYFNVYGPRETHKGRMASVAFHNFNQFRADGTVKLFGEYGGYGPGMQSRDFISVEDVVKVNLFFFDHPEKSGIFNLGTGRAQPFNDIAATVVNTLREAEGKPPLSLDDLVQEGLVEYVKFPDALRGKYQCFTQSDVSKLRGAGYSERFLSVEEGVARYCRWLLERNG
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: PYRF_SULSY
Sequence: MKKLALALDVNDINQALEIVDEIQDKIIIKIGYNLFIKGGINFVKQIKDRGFDIFLDLKLHDIPNTVYNGVKAVSEIGVNYLTIHSLGGQEMIQQAVKAKEGTDLKILAVTILTSHDENYPKLLGSSLSVPDLAYRLADMAVSNGSDGIVCSSHEVKFLKEHIQKPFIAVVPGIRLTKEKTDDQTRIATPEEALRDGADIIVVGRPILKAEDRNKIIKEMLSVIEEL
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: SUFE_SHIB3
Sequence: MALLPDKEKLLRNFLRCANWEEKYLYIIELGQRLPELRDEDRSPQNSIQGCQNQVWIVMRQNAQGIIELQGDSDAAIVKGLIAVVFILYDQMTPQDIVNFDVRPWFEKMALTQHLTPSRSQGLEAMIRAIRAKAAALS
What is the function of this protein?
Participates in cysteine desulfuration mediated by SufS.  Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.
What are the official names of this protein?
Cysteine desulfuration protein SufE.
What is the protein family that this protein belongs to?
Belongs to the SufE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD_SHESW
Sequence: MDKVKIALQYMLPKHLLSRLVGKLAAAEAGTLTTAAIKWFIKQYKIDMSEAAQSEPQAYKSFNDFFTRALKPGIRPINQHTHIMVHPVDGAVSQLGPIKEGRIFQAKGHHYSSLTLLGDQAQDAKRFEGGDFATIYLAPKDYHRIHMPIKGTLSKMTYVPGELFSVNPLTARHVPGLFARNERVVAIFETEHGPLAMVLVGATIVASIETVWAGTITPPTGKQVFTWEYPTVGPDAITLDKGDEMGRFKLGSTVVMLFAKDAIDTFAEGVEAEAVTRMGQAFANLNNPK
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DAPB_BURM1
Sequence: MKIAIAGASGRMGRMLIEAVLNDADAQLVGALDRAGSPSLGQDAGAFLGKDTGVKLTDDIDAVFAQADYLIDFTRPEGTLAHVEAALRHDVKLVIGTTGFTAEQKAVLHAAAEKVAIVFAANMSVGVNVTLKLLEFAAKHFSHGYDIEIIEAHHRHKVDAPSGTALMMGEAVAGALGRSLDDCAVYGRHGVTGERDPSTIGFAAVRGGDIVGDHTVLFAGIGERIEITHKSSSRVSYAQGALRAVRFLSARDTGLFDMQDVLGLR
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POMP_HUMAN
Sequence: MNARGLGSELKDSIPVTELSASGPFESHDLLRKGFSCVKNELLPSHPLELSEKNFQLNQDKMNFSTLRNIQGLFAPLKLQMEFKAVQQVQRLPFLSSSNLSLDVLRGNDETIGFEDILNDPSQSEVMGEPHLMVEYKLGLL
What is the function of this protein?
Molecular chaperone essential for the assembly of standard proteasomes and immunoproteasomes.  Degraded after completion of proteasome maturation.  Mediates the association of 20S preproteasome with the endoplasmic reticulum.
What are the official names of this protein?
Proteasome maturation protein, Proteassemblin, Protein UMP1 homolog, hUMP1, Voltage-gated K channel beta subunit 4.1.
What is the protein family that this protein belongs to?
Belongs to the POMP/UMP1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Microsome membrane.
Protein: CNIH2_DANRE
Sequence: MAFTFAAFCYMLTLVLCAALIFFVIWQIIAFDELRTDFKNPIDQSNPTRARERILNIERICNLLRRLVVPEYSIHGLFCLMFMCAGEWVTLGLNIPLLLYHLWRFFHRPADGSEVMYDPVSVMNADILNYCQKESWCKLGFYLLSFFYYLYSMVYALVSF
What is the function of this protein?
Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs).
What are the official names of this protein?
Protein cornichon homolog 2, CNIH-2, Cornichon family AMPA receptor auxiliary protein 2.
What is the protein family that this protein belongs to?
Belongs to the cornichon family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ACCD_SYNR3
Sequence: MSLLDWFADRRKTAPALRPTPEPDEGDGLWSKCPECGEVVYRKDLIANASVCASCGYHHRIHSEERLRILLDPGSFIPVDGELSPTDPLAFKDRRAYADRLRDSQRQTGLRDAVVCGTGTIEGQGIALAVMDFRFMGGSMGSVVGEKITRLIETATEQQLPVLVVCASGGARMQEGMLSLMQMAKISGALERHRSRKLLYIPLLTHPTTGGVTASFAMLGDLILAEPKALIGFAGRRVIEQTLREKLPDNFQTAEYLQDHGFVDAIIPRTQLRSRLASLLQMHQQPAAVSA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_BURCH
Sequence: MAIERTLSIIKPDAVAKNVIGQIYSRFEGAGLKIVASRMAHLSRADAEKFYAVHAARPFFKDLVDFMISGPVMIQVLEGEGAILKNRDLMGATDPKKAEKGTIRADFADSIDANAVHGSDAAETAAVEIAFFFPEMNVYSR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.