PharMolix/UniProtQA huggingface dataset:
Protein: RUVA_COREF
Sequence: MIASLRGTVISIGLGTAVIECQGVGYEVTTTPTTLARLQRGEEATLLTTMVVREDAMKLYGFIDDQSREMFALLQTVTGLGPRLALACESVLTPLEIAQAIAGGDAKTLQRVPGVGKRMADRLIVELKDKVAAYTVGVVDDGAPTAPTQGVAPVVVVDQVTQALTGLGFTEKQADDAVAAVLSADPGLDTSAALRAALAKLGGK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: GLO2_RHILO
Sequence: MAVEIEQFMCRSDNFGVLVHDPKSGQTAIIDAPEEAPILAAIKRTGWTPTMILTTHHHMDHVEANLALKERFKLRIVGPEAEKAKIPGIDETVEEGSVLHLGDERIEVIATPGHTAGHVSYHLPASKVAFTADTLFALGCGRLFECKPPVMYESLRKLAALPAATTIYCGHEYTLANARFALTVDPTNSALKERATRIEALRVDNKPTLPTTIGEELSTNPFLRWHDPAIRKHLGMEKAGDAEVFAEIRKRKDNF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: TRUD_PYRFU
Sequence: MSDPVGGLKYLTTSPGIGGKIKVYPEDFIVKEVIPKSIFKAGKCKIYILKKKNWETMAAIKEIAKRVGVHYSEIGFAGTKDRHAVTYQYISICRDVNLEEVKIRDIELKFVGYGRPLKLGFLLGNFFKIRVRESNPSLLPSVIEEAKEKGGFPNYFGIQRFGEKRSVNHVVGKLLLLGKYEEAAEVFLGFPGKGMEGDEARRKFLETKDVDLALREFPNFLRYERAMLYRYKETGSWKKAFLVLPRPILRIFIHSFQSYLFNLYLSRRIEEGLPLNKALPGDIVIQVKKGIPLRKRTYRVTENNVDFVNRKIKEGEAMVSGPIFGYMYRKGKGIPGRLEEEILEEAGVKLEYFKKLPKPMREPGGRRELLIRPMKFAYKVEDRDVIFRFFLPKGVYATSVLREIMKN
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: ATPA_MYCMM
Sequence: MAELTISANDIQSAIEEYVGSFTSDTSREEVGTVVDAGDGIAHVEGLPSVMTQELLEFPGGVLGVALNLDEHSVGAVILGNFENIEEGQQVKRTGEVLSVPVGDAFLGRVINPLGQPIDGRGDIEAETRRALELQAPSVVQRQSVKEPLQTGIKAIDAMTPIGRGQRQLIIGDRKTGKTAVCVDTILNQRQNWETGDPKKQVRCVYVAVGQKGTTIASVRRALEEGGAMDYTTIVAAPASDSAGFKWLAPYTGSAVAQHWMYDGKHVLIVFDDLTKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDELGGGSLTGLPIIETKANDISAYIPTNVISITDGQCFLETDLFNQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQYRELEAFAAFASDLDATSKAQLDRGARLVELLKQPQYQPMPVEEQVISIFLGTGGHLDSVPVEDVRRFETELLDHIRASEENLLSTIRDTQKLTEETEEALTKVINHFKKGFASSTGESVVPDEHVEAMDEEDLGKESVKVKKPAPQKKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ZFPL1_DROME
Sequence: MGLCKCPKRLVTNQFCFEHRVNVCEHCMVQSHPKCIVQSYLQWLRDSDYISNCTLCGTTLEQGDCVRLVCYHVFHWDCLNARQAALPANTAPRGHQCPACSVEIFPNANLVSPVADALKSFLSQVNWGRNGLGLALLSEEQSSSLKAIKPKVASQAAVSNMTKVHHIHSGGERERTKPNGHDAVSPHSVLLMDAFNPPSAGDYASSRRPLLPRQSPIGGTDRDDNKYQRRTPAELFSRWTRRFYAPSSRPPWRRTWFLVTAGILAFVLFVYLMAWLGRGGSDAVDEGWNNPNPQPNHYE
What are the official names of this protein?
Zinc finger protein-like 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the ZFPL1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: LEPA_ECOLI
Sequence: MKNIRNFSIIAHIDHGKSTLSDRIIQICGGLSDREMEAQVLDSMDLERERGITIKAQSVTLDYKASDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAMEMDLEVVPVLNKIDLPAADPERVAEEIEDIVGIDATDAVRCSAKTGVGVQDVLERLVRDIPPPEGDPEGPLQALIIDSWFDNYLGVVSLIRIKNGTLRKGDKVKVMSTGQTYNADRLGIFTPKQVDRTELKCGEVGWLVCAIKDIHGAPVGDTLTLARNPAEKALPGFKKVKPQVYAGLFPVSSDDYEAFRDALGKLSLNDASLFYEPESSSALGFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVETTSREVIYVDSPSKLPAVNNIYELREPIAECHMLLPQAYLGNVITLCVEKRGVQTNMVYHGNQVALTYEIPMAEVVLDFFDRLKSTSRGYASLDYNFKRFQASDMVRVDVLINGERVDALALITHRDNSQNRGRELVEKMKDLIPRQQFDIAIQAAIGTHIIARSTVKQLRKNVLAKCYGGDISRKKKLLQKQKEGKKRMKQIGNVELPQEAFLAILHVGKDNK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: BTN1_CHAGB
Sequence: MNRSPSTSGLLPLPGTPSSSWALYRARLSNMFRNTDVSVVIAFWLFGLINNILYVLVLSAAQDLVGTSVPKGAVLLADVLPSFLTKLVAPYFIHRVPYSVRIAVFVALSCAGMLVVAAAPVEGAVGVKLLGVVLASLSSGGGELSFLGLTHYYGHGSLAAWGSGTGGAGLVGAGLYVVLTGWIGLGVRGSLLVGALLPSVMVVAFWGILPRGPLKGWKGGYERVAEPGEEEDGEEGFEDVPAGAASAGLLAPGPSVAATAYTHHHEGRTGRASFWGNVRRARALFFPYMLPLLLVYVAEYTINQGVAPTLLFPLDQSPFSEFREYYPFYGFLYQLGVFISRSSTPFIRIHHLYLPSFLQVANLVLLTLHAVLNFIPSVYLVFVVIFWEGLLGGAVYVNTFAEIMENVPAEDREFSLGATSVSDSGGICIAGFLGMAMEVWLCRWQVSQGRDYCRRIEAS
What is the function of this protein?
Involved in vacuolar transport and vacuole pH homeostasis.  Also required for cytokinesis (By similarity).
What are the official names of this protein?
Protein BTN1.
What is the protein family that this protein belongs to?
Belongs to the battenin family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: PMA6E_HUMAN
Sequence: MALAMLRDWCRWMGANAERSLLILGIPDDCKEHEFQEAVRAALSPLGRYRVLTKHFRKELGAKAALVEFAEYLNRSLIPHQIPGNGGPWKVIFLPQVPVIEFQDMPSFPAQPQGQAVAKAAGEGGGAGEAGGVGEVGAAGEAGGTGEAGATGEAGAAGEAGGAGEAGGVGEAGAAGEAGGAGEAGAAGEGGAAGEAGGAGEAGGVGEAGAAGEAGGAGEAGGVGEAGAAGEAGGAGEAGAAGEAGGAGEGRAAGEAGAAGEAGAVGEAGAAGEAGAVGEAGAAGEAGAVGEAGGTNVTKAWVQPWRCTLQPVLENRAYRELRPFSRREQPGCEEESFESWVEHAKDMLQLWCHASEREKKRWLLESLGGPALEVVSGLLEEDTNLSALDCLAALGQVFRNQDTRMTSRLKFLTCTQGPQEGLFAFVVRLEGLLQRAVEKGAVCPALANYLRLQQVLSWARPSEALQDTLRGMQLEKRPPGFLGLLRLIREMEAWAAFPARSQQGVAWAAAPVESEDPAAAQASPAQGNASEAGPGAEDAAEAASATKEAARGAPAAGEGESAPAGPEGLGQARPIEVPWGSSPARMSSAVWVFPRGLSWGPEGLIQVRGQEARKPPLEGLQTILEEPENEDEDGAGDEGQPKSSQGK
What are the official names of this protein?
Paraneoplastic antigen Ma6E.
Protein: EFG_BACMK
Sequence: MTREFSLENTRNIGIMAHIDAGKTTATERILYYTGRIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWKGHRVNIIDTPGHVDFTVEVERSLRVLDGAVAVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKIGADFLYSVGTIHDRLQANAHPIQLPIGAEDEFNGIIDLVEECAYMYSNDLGTDIERVEIPEEHKELAEEYRGKLIEAVAELDEEMMMKYLEGEEITVEELKAGIRKATTSVEFFPVICGSAFKNKGVQILLDAVIDYLPSPLDVPAIKGTLPDTEEAIERKSSDEEPFAALAFKIMTDPYVGKLTFFRVYSGVLNSGSYVKNSTKGKRERVGRILQMHANSREEISTVYAGDIAAAVGLKDTTTGDTLCDEKSLVILESMEFPEPVISVAIEPKSKADQDKMGTALSKLSEEDPTFRAHTDQETGQTIIAGMGELHLDIIVDRMRREFKVEANVGAPQVAYRETFRAAAKVEGKFARQSGGRGQFGHVWIEFEPNEEGKGFEFQNKVVGGVVPREYIPAVGAGLEDALKNGVLAGYPLVDIKAALVDGSYHDVDSSEMAFKIAASMALKAAVSKCSPVILEPMMKVEVVIPEEYMGDIMGDVTSRRGRVEGMEARGNAQVVRAMVPLSEMFGYATALRSNTQGRGTFSMTFDHYEEVPKSVSEEIIKKNKGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE2_POLSJ
Sequence: MTPGELFTDGPDHVLNAGRRTLTLVVQNTADRPIQVGSHYHFAETNAALGFDRQAAHGMRLNIASGTAVRFEPGQQRTVELVDYAGERKVFGFRGLVQGGLDASGQSHKETT
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_COXBR
Sequence: MSQARTLHRLIAPAVEALGFELVGCELFRRGATTILQVFVDKPGGIGLDECAKVSRQISAVLDVEDPIRGRYTLEVSSPGLERPLYTANHYRRFIGNKAKIRLREPREGQRQFRGMVVAVDNEEQVTLQLDNKILKVSLGEIEKANLIADFEG
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4C_LOTJA
Sequence: MNYFPWLTLVVILPIAGGSLIFLFPHRGNKVIRWYTVCICLIDLLLTTYAFCYHFQLDDPLIQLTESYKWINFFDFYWRFGIDGLSIGPILLTGFITTLATLAAQPITRECKLFYFLMLAMYSGQIGPFSSRDILLFFIMWELELIPVYLLLAMWGGKKRLYSATKFILYTAGSSVFLLMATLGIGLYGSNEPTLNFETLNNQSYPLALEIIVYIGFLIAFAVKSPIIPLHTWLPDTHGEAHYSTCMLLAGILLKMGAYGLVRINMELFSHAHSIFCPWLMILGSIQIIYAASASLGQRNLKKRIAYSSVSHMGFLIIGIGSISDTGLNGAILQIISHGFIGAALFFLSGTSYDRLRLLYLDEMGGMALPMPKIFTVFTILSMASLALPGMSGFFAELIVFWGIITSQKYFLIMKILITFVTAIGMILTPIYSLSILRQMFYGYKFFNTPNSYFFDSGPRELFISISILIPIIGIGIYPDFIFSFSVDKVEAVLSHF
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4, chloroplastic, NAD(P)H dehydrogenase, chain 4, NADH-plastoquinone oxidoreductase chain 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: UREG_DEIRA
Sequence: MTPLKIGVGGPVGSGKTALLEVLCRELRDRYDLAVITNDIYTFEDQRILTRAAALAPERIRGVQTGGCPHTAIREDSSLNQETVEALQGEFPGLELLFIESGGDNLASSFSPELVDAWLFVLDVAGGEKVPRKGGPGIRHSDLLVINKTDLAPLVGADLRVMDADARAQRRAGDEVRPYVFTNLKSGAGVDEIIAWIEHDLLFRDVTPPRVGL
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_STRCO
Sequence: MTRPSVSTFKAPKGTYDLLPPDSAKFLAVREAIAAPLRNSGYGYIETPGFENVELFARGVGESTDIVTKEMYVFETKGGDRLALRPETTAPVLRAVLEANLHKAGNLPVKVWYSGSQYRYERPQKGRYRHFSQVGAEAIGAEDPALDAELIILADQSYRALGLQDFRILLNSLGDQECRPVYRAALQDFLRGLDLDEETLRRAEINPLRVLDDKRPDVQKQLTEAPLLRDYLCDACKAYHEEVRELITAAGVVFEDDPKLVRGLDYYTRTTFEFVHDGLGSQSAVGGGGRYDGLSEMIGGPSLPSVGWALGVDRTVLALEAEGIELDIPSATSVFAVPLGEEARRILFAKVTELRKNGVAADFSYGGKGLKAAMKAANRSGARYTLVLGERDLAEGVVQLKDMESGEQTAIGVNEIVAELESRLG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HILD_SALTS
Sequence: MENVTFVSNSHQRPAADNLQKLKSLLTNTRQQIKSQTQQVTIKNLYVSSFTLVCFRSGKLTISNNHDTIYCDEPGMLVLKKEQVVNVTLEEVNGHMDFDILEIPTQRLGALYALIPNEQQTKMAVPTEKAQKIFYTPDFPARREVFEHLKTAFSCTKDTSKGCSNCNNKSCIENEELIPYFLLFLLTAFLRLPESYEIILSSAQITLKERVYNIISSSPSRQWKLTDVADHIFMSTSTLKRKLAEEGTSFSDIYLSARMNQAAKLLRIGNHNVNAVALKCGYDSTSYFIQCFKKYFKTTPSTFIKMANH
What are the official names of this protein?
Transcriptional regulator HilD.
Protein: COF1_HUMAN
Sequence: MASGVAVSDGVIKVFNDMKVRKSSTPEEVKKRKKAVLFCLSEDKKNIILEEGKEILVGDVGQTVDDPYATFVKMLPDKDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASSKDAIKKKLTGIKHELQANCYEEVKDRCTLAEKLGGSAVISLEGKPL
What is the function of this protein?
Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity (PubMed:11812157).  In conjunction with the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics (PubMed:15580268).  Required for the centralization of the mitotic spindle and symmetric division of zygotes (By similarity).  Plays a role in the regulation of cell morphology and cytoskeletal organization in epithelial cells (PubMed:21834987).  Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (PubMed:23633677).  Required for neural tube morphogenesis and neural crest cell migration (By similarity).
What are the official names of this protein?
Cofilin-1, 18 kDa phosphoprotein, p18, Cofilin, non-muscle isoform.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
What are the subcellular locations of this protein?
Nucleus matrix. Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium. Cell projection, growth cone. Cell projection, axon. Note=Colocalizes with the actin cytoskeleton in membrane ruffles and lamellipodia. Detected at the cleavage furrow and contractile ring during cytokinesis. Almost completely in nucleus in cells exposed to heat shock or 10% dimethyl sulfoxide.
Protein: STC2_PONAB
Sequence: MCAERLGQFMTLALVLATFDPARGTDATNPPEGPQDRSPQQKGRLSLQNTAEIQHCLVNAGDVGCGVFECFENNSSEIRGLHGICMTFLHNAGKFDAQGKSFIKDALKCKAHALRHRFGCISRKCPAIREMVFQLQRECYLKHDLCAAAQENTRVIVEMIHFKDLLLHEPYVDLVNLLLTCGEEVKEAITHSVQVQCEQNWGSLCSILSFCTSAIQRPPTAPPERQPQVDRTKLSRAHHGEAGHHLPEPSSRETGRGAKGERGSKSHPNAHARGRVGGLGAQGPSGSSEWEDEQSEYSDIRR
What is the function of this protein?
Has an anti-hypocalcemic action on calcium and phosphate homeostasis.
What are the official names of this protein?
Stanniocalcin-2, STC-2.
What is the protein family that this protein belongs to?
Belongs to the stanniocalcin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS17_STRGG
Sequence: MSEKTVTETNTDRGFRKTREGLVVSDKMDKTVVVAVEDRVKHALYGKVIRRTNKLKAHDEQNSAGVGDRVLIMETRPLSASKRWRIVEILEKAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: NDK_STAA3
Sequence: MERTFLMIKPDAVQRNLIGEVISRIERKGLKLVGGKLMQVPMELAETHYGEHQGKPFYNDLISFITSAPVFAMVVEGEDAVNVSRHIIGSTNPSEASPGSIRGDLGLTVGRNIIHGSDSLESAEREINLWFNENEITSYASPRDAWLYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSJ_YERP3
Sequence: MTTQAPPTSLLPLSPEQLARLQAAVGEFSPTQMAWLSGYFWGRVNQQPGAVASPAVAAPPPVTVTLISASQTGNARRLAEQLRDDLLAAQLSVNLVNAGDYKFKQIAQERLLVVVASTQGEGEPAEEAVALHKFLFSKKAPKLPETAFAVFGLGDTSYEHFCQAGKDFDSKLAELGAQRLLDRVDADVEYQVQAQQWRQQVVATLQAKVPAQSTAPTQFIAPTQSTTPAAAAITSGGTTTVSPYSKTAPLTAQLSVQQKVTGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWFDNDPALVEELLALLWLKGDEPVSIDGQNMPLAQALLSHLELTQNTTLIVDKYAALSRDETLIALLADKPALQLYAKNTPFVDMVRQAPSDLNADQLVGLLRPLTPRLYSIASSQAETENEVHITVGVVRYDIDGRARSGGASGYLADRLEVDGDIRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAFMQQREVDGASGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLTRIDLAWSRDQAHKIYVQDKLREQGAELWNWIQQGAHIYVCGDANRMAKDVEQVLLDVVALHGAMDAEQADEYLSELRQARRYQRDVY
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.  The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
What are the official names of this protein?
Sulfite reductase [NADPH] flavoprotein alpha-component, SiR-FP.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: NDK_RHOCS
Sequence: MAVERTLSIVKPDATRRNLTGKINARFEEAGLRIVAQKRIRLTREQAEQFYIVHAERPFYGELVSFMISGPVVVQVLEGENAVARNREIMGATNPANAAPGTIRKDFAESIEANSVHGSDSLENAATEIAYFFSGTEIVG
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSY_PSEPW
Sequence: MFWLLALLAYLLGSLSFAIVLSRLSGSPDPRSCGSGNAGATNMLRLAGRKMAILTLLGDLCKGLLPVMLARLAGLDLQEQAWVGVCAVLGHLFPVYFRFQGGKGVATAAGMLMGLYFPAALLAIAAWLLTFYLTRTSSLAALIATPLTLPLLAWREPAALLPISVLTVMIVWRHRNNLRDLFAGRERHF
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TA2R5_PAPHA
Sequence: MLSAGLGLLMLVAVIEFLIGLIGNGILVVWSLREWIRKFSWSSYNLIILGLAGCRFLLQWLIILDLSLFPLFQSSSWLRYLNVFWVLVSQASLWFATFLSVFYCKKITTFDRPAYLWLKQRAYNLSLWCLLGYFIISLLLTVQVGLTVHHPPQGNSSIRYPFEHWQYLYVFQLNSGSYLPLMVFLVSSGMLIISLYTHHKKMKVHSAGRRDARAKAHITALKSLGCFLLLHLVYIVASPFSITSKTYPPDLTSVFIWETLMAAYPSLHSLMLIMGIPRVKQTCQKILWKTVCARRCWGP
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 5, T2R5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y143_NOVAD
Sequence: MGDPRISHIELDEATIIWRNADIEQERRIAIFDLIEENTFKPLRAFEAGHEGPYRLKLSVEDGRLALTVSDDDGNGGGQLLETVILGLGRFRRPIREYFAICDSYYQAIRKATATEIETIDMARRGVHNEAAEMLLERLQGKIDTDFATARRLFTLICVLHIRG
What are the official names of this protein?
UPF0262 protein Saro_0143.
What is the protein family that this protein belongs to?
Belongs to the UPF0262 family.
Protein: CASPC_MOUSE
Sequence: MAARRTHERDPIYKIKGLAKDMLDGVFDDLVEKNVLNGDELLKIGESASFILNKAENLVENFLEKTDMAGKIFAGHIANSQEQLSLQFSNDEDDGPQKICTPSSPSESKRKVEDDEMEVNAGLAHESHLMLTAPHGLQSSEVQDTLKLCPRDQFCKIKTERAKEIYPVMEKEGRTRLALIICNKKFDYLFDRDNADTDILNMQELLENLGYSVVLKENLTAQEMETELMQFAGRPEHQSSDSTFLVFMSHGILEGICGVKHRNKKPDVLHDDTIFKIFNNSNCRSLRNKPKILIMQACRGRYNGTIWVSTNKGIATADTDEERVLSCKWNNSITKAHVETDFIAFKSSTPHNISWKVGKTGSLFISKLIDCFKKYCWCYHLEEIFRKVQHSFEVPGELTQMPTIERVSMTRYFYLFPGN
What is the function of this protein?
Involved in the activation cascade of caspases responsible for apoptosis execution.
What are the official names of this protein?
Caspase-12, CASP-12.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14A family.
Protein: RL13_AGARV
Sequence: MKTFMASPATIDRKWYVVDAEGKTLGRLASEVAKVLRGKNKAIFTPHIDTGDYVIVVNADKVKVTGKKLDQKIYYHHSDYIGGMKETTLREMMNKHPERVIEYAVKGMLPKGPLGRQMYTKLFVYAGPDHKHAAQKPETLEF
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RAPA_HISS2
Sequence: MLFAIGQRWISESENSLGLGIITGQDNRTVTISFPASDEIRIYALASAPLTRVLFQKGDEITHQLGWKAKVVDVMIRNELAFYLVQRLDNNEEIAVQEMELAHQISFSKPQDRLFSTQIDRNEHFVLRYKALKHQQEQFQSSLRGLRGNRAGLIPHQLHIAQEVGRRIAPRVLLADEVGLGKTIEAGMILQQQLLAEKVQRVLILVPETLQHQWLVEMLRRFNLHFSLFDEERCADFDNPEDHVEANPFVAENLIICALDWLVQQPKRAKQALAGEFDLLIVDEAHHLTWSEDSPSIAYELVMQLSAVIPAVLLLTATPEQLGQQSHFARLHLLDPNRFYSYRAFEKEQQQYQPVAKAVQSLLSEHILTVEEQNHLAELLSEQDIEPMLKVINSQADTEQKQVARGELMSNLIDRHGTGRLLFRNTRQGVQGFPHRIYHQIKLDLPTQYQNAINVLKMLGEIKDPELFYPEQIFQKMNADATWWRFDPRVDWLIHLVKSLREEKILVICQDAITATQLEQALREKEGIRSAVFHENMSIIERDRASAYFAQQEEGAQVLLSSSIGSEGRNFQFACHLVLFHLPNNPDLLEQCIGRLDRIGQRRDIQIYVPCFADTPQIRLAQWYHEGLNAFEETCPMGAILHEKCGAKLTEFLTSDTTDDFQSFIQQTHQQQLQLKSELEQGRDRLLELNSNGGIQAQQLANDIAIQDGSTELIDFTLNLFDIIGVEQEDLGEKSIVISPTGTMLVPDFPGLKEEGVTVTFDRDLALAREELEFLTWDHPIVRNGIDLIVSGDIGKSAVALLVNKQLPTGTLLLELVYIIESQSPRGLQLTRFLPPTPLRLLLDIKGNDLSHQISFQGLQKQLKPMGKNMATKVIKIMRPAIEQLIKQSEKNVVEPAKMIIEQAKQLADQSLSAEINRLYALQAVNKNIRPEEIEQLESQRTLSLELLNQANWRLDSLRVIVSNKE
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: NFI_SALNS
Sequence: MDLASLRAQQIELASSVCREDRLDKDPPAFIGGADVGFEQGGEVTRAAMVLLKYPSLELVEYKVARIATTMPYIPGFLSFREYPALLAAWEQLSQKPDLLFVDGHGISHPRRLGVASHFGLLVDVPTIGVAKKRLCGKFEPLSTEPGALSPLMDKGEQLAWVWRSKARCNPLFIATGHRVSTDSALAWVQRCMKGYRLPEPTRWADAVASGRPAFVRWQEIQR
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.