PharMolix/UniProtQA huggingface dataset:
Protein: RLMH_PSEPF
Sequence: MRLRLIAVGSRMPKWVEEGWHEYAKRLPSELAMELVEIPLNTRGKNADVARFIRQEGEAMLAKVGQNERIVTLEVHGKPWSTEQLAVELDRWRLDSRTVNFMVGGPEGLAPEVCARADQRWSLSPLTLPHPLVRILIGEQLYRAWTVLSGHPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSM6_MOUSE
Sequence: MSLRKQTPSDFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQTEEYVNGQLKNKYGDAFIRGNNVLYISTQKRRM
What is the function of this protein?
Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).  The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.  Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates.  Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway.
What are the official names of this protein?
U6 snRNA-associated Sm-like protein LSm6.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: WTF21_SCHPO
Sequence: MKNNYTSLKSPLDEEDELKTDHEIDLEKGPLPEYDSEEEGALPPYSDHALVNNPPNTHRENNPSRSTDNSSPFLIKLLISFTPIYVLNVLAICYLTYKDAFFKDYGAAEWTLFGFWCLVCTLALIFLTYFYETWVKAVKVTVISLAKCVKVISIGLFNIRREMMIIIWILWLIICCILFVYIKSGDLILNKALICSTCTISAVLLLIVSSVCIPFWTFERTLAKLAKVLLLQSGIVLVLNGTMFLRGKHFERIGCEIEASVLFIMGNVLFLCEMECPGALIRTRNSIRNGIAFILGGIGNAMMGLANAIRGANDNNDIPLGEMDVESEV
What is the function of this protein?
Acts as a suppressor component of the dual wtf meiotic drive system, and can suppress but not confer meiotic drive by compatible poisons (By similarity).  Wtf meiotic drive systems promote unequal transmission of alleles from the parental zygote to progeny spores by encoding a poison and an antidote from the same locus; the poison is trans-acting and forms toxic aggregates in all spores within an ascus, wherease the antidote is spore-specific and targets aggregates for degradation by the vacuole (By similarity).  Meiotic drive by wtf systems therefore lead to poisoning of all progeny that do not inherit the dual poison/antidote allele, or express a compatible antidote (By similarity).
What are the official names of this protein?
Meiotic drive suppressor wtf21.
What is the protein family that this protein belongs to?
Belongs to the WTF family.
What are the subcellular locations of this protein?
Spore membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein.
Protein: RUVA_JANMA
Sequence: MIGRLSGVLLEKNPPQLLVDCNGVGYEVNVPMSTFYNLPGLGDKVVLLTHLTVREDAHILFGFGTNEERNVFKQLVKITGIGARTALSILSGMSVADLAQAITMQEAGRLTKIPGIGKKTAERLLLELKGKLGADLGVAGAVATDATSDILNALLALGYSDKEAMLALKQVPAGTGVSDGIKLALKSLSKA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: NDB4S_OPICY
Sequence: MKAQLCILLIALVLFQTFSQSDAILSAIWSGIKSLFGRRGLNDLDDLDELFDGEISQADVDFLNELMR
What is the function of this protein?
Antimicrobial peptide (By similarity) (PubMed:27917162).  Inhibits the growth of Gram-positive and Gram-negative bacteria (By similarity).  Shows antifungal activity with MIC values ranging from 12. 5 to 25 uM (PubMed:27917162).  Shows also an inhibitory activity on C. albicans biofilms at high concentrations (PubMed:27917162).  Shows low cytotoxic activity and has weak hemolytic activity (PubMed:27917162).
What are the official names of this protein?
Amphipathic peptide OcyC1, Non-disulfide-bridged peptide 5.7, NDBP-5.7.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short antimicrobial peptide (group 4) family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms an alpha-helical membrane channel in the prey.
Protein: SYE1_CAMJJ
Sequence: MYRFAPSPTGDMHIGNLRAAIFNYICARQKNMDFILRIEDTDKARNIAGKEEEIKEILNLFGISWQHYYIQSENLKFHRQMALKLVSEKKAFACFCTEEELEAKKELAKKQGKAYRYDGTCEKLADIDVLECEKPFVIRLKKPTHTMKFTDFIKGELSFEPENIDSFVIMRTDKTPTYNFACAVDDMLENVTCIIRGEDHVSNTPKQEHIRASLGYNKAMTYAHLPIILNEEGVKMSKREAHSSVKWLLESGILPSAIANYLIMLGNKTPCEIFTLEEAIKWFDISKVSKAPARFDLKKLLQINREHIKMIKDDELNKILDLNKDLAQLAKFYTQEASTIKELKEKMRAIFNTKDFGEFETECKILKELLKDIELFENYEDFKNELLSKSDLKGKKFFMPLRIILTGNIHGPELSDLYPYIKNFIHELARI
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_SHEAM
Sequence: MFNENPIKRRPSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVAATVAQIRALENVGADIVRVSVPTMDAAEAFRQIKQQVKVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRAVVDCARDKNIPIRIGVNGGSLEKDLMDKYKEPTPEALLESAMRHVDILDRLNFDQFKVSVKASDVFLAVESYRLLAKQIKQPLHLGITEAGGARAGAVKSAVGLGMLLAEGIGDTLRISLAADPVEEVKVGFDILKSLRIRSRGINFIACPSCSRQEFDVISTVNELERRLEDVTTAMDVSIIGCVVNGPGEALVSHLGLAGGHKKSGYYDDGIRQKERFDNDNLVDALEAKIRAKASLMANRIPVQEGDAD
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: SECB_BLOPB
Sequence: MFFVLESNSNNVLFRIQRIYIKDISFEAPNTPGVFQINWNPKIKVDLNSDAKNIHIDMYEVVLCVTVTAKIEDDTAFLCQVKQAGIFNVSGLNKTQMIRCLKVHCPTILFPYASECVSNQVSRGTFPQLNLDPINFDILFIQSLQKKYNDTLKI
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_EHRCJ
Sequence: MFITFEGIDGSGKTTQSHLLTEYLSKIYGVNNVVLTREPGGTLLNEAVRDLLFQAKGLDSLSELLFFIAMRREHFMKVIKPSLMQKKIVVCDRFIDSTIAYQGYGQGIDCNLICQLNDLVVDMYPDITFVIDVDVHESLSRSCKNGYEFAELEFYYRVRNGFYSIVEKNPHRCHIITDNNEICDIDGINLIHLKIVKVLQMV
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: SPC29_CANGA
Sequence: MVVGPISNLRDDALKDDTLNHIRKEYLESKKQISNLLSQETNTNEFSRKPYPNSSPIRKFDHFANERPTTIDAKLREQLRTGASDVAIEQSLRTNSDESRNQMIYDDMKVMKRIIDGQQESIRELRRALEQERYMNSELQRKYNEMERRFDRLEWFINSHDKFQAYQDIRSNTTKKDFSDPIFNNGLKRRWDEYPIRSFEPDTNINRNNRIFSNYDDSTTRLMQITDPHYRSVG
What is the function of this protein?
Component of the spindle pole body (SPB) required for the proper execution of spindle pole body (SPB) duplication.  Links the central plaque component SPC42 to the inner plaque component SPC110 (By similarity).
What are the official names of this protein?
Spindle pole component 29.
What is the protein family that this protein belongs to?
Belongs to the SPC29 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein: EFP_SALHS
Sequence: MATYYSNDFRSGLKIMLDGEPYAVESSEFVKPGKGQAFARVKLRRLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGDNAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFVQIGEVIKVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMK_SALTI
Sequence: MKIAILSRDGTLYSCKRLREAAMRRGHLVEILDPLSCYMNINPAASSIHYKGRRLPHFDAVIPRIGSAITFYGTAALRQFELLGSYPLNESVAITRARDKLRSLQLLARQGIDLPITGIAHSPDDTSDLIKMVGGAPLVVKLVEGTQGIGVVLAETRQAAESVIDAFRGLNAHILVQEYIAEAKGCDIRCLVVGNEVVAAIERCAKAGDFRSNLHRGGVASIATITPRERDIAIKAAQTLGLDVAGVDILRAARGPLVMEVNASPGLEGIEKTTGVDIAGRMIQWIERHATPEFCLKIGG
What is the function of this protein?
Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF).  Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate.  The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH.
What are the official names of this protein?
Ribosomal protein S6--L-glutamate ligase, Poly-alpha-glutamate synthase, Ribosomal protein S6 modification protein.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: THH1_ARATH
Sequence: MRSGGLEMMSSSAIVAFNLKEGKNWWWDVNESPVWQDRIFHVLAVLYGIVSVIAVIQLVRIQLRVPEYGWTTQKVFHFLNFMVNGVRALVFLFRRDAQNMQPEILQHILLDIPSLAFFTTYALLVLFWAEIYYQARAVSTDGLRPSFFTINAVVYVIQIALWLVLWWKPVHLMVIISKMFFAGVSLFAALGFLLYGGRLFLMLQRFPVESKGRRKKLQEVGYVTTICFTCFLIRCIMMCFDAFDDAADLDVLDHPILNFIYYLLVEILPSSLVLFILRKLPPKRGITQYHQIQ
What is the function of this protein?
Contributes to the intracellular multiplication of tobamoviruses, probably being a membrane anchor promoting the formation of the replication complex.
What are the official names of this protein?
Protein TOM THREE HOMOLOG 1.
What is the protein family that this protein belongs to?
Belongs to the plant tobamovirus multiplication TOM1 protein family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: NEMO_PIG
Sequence: MSRTPWKSQPCEMVQPSGGPAGDQDVLGEESSLGKPTMLHLPSEQGAPETFQRCLEENQELRDAIRQSNQMLRERCEELQRFQGSQREEKEFLMQKFCEARRLVERLSLEKLELRRQREQALQEVELLKTCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKERQALESRVRATSEQVRQLENEREALQQQHSVQVDQLRLQSQSMEAALRMERQAASEEKRKLAQLQVAYHQLFQEYDNHIKSSVVSSERNRGLQLEDLKQQLQQAEEALVAKQEVIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERQAREQLAERKELLQEQLEQLQREYSRLKTSCQESARIEDMRKRHVEVSQPTLPPAPAHHSFHPALPSQRRSPPEEPPNFCCPKCQYQAPDMDTLQIHVMECIE
What is the function of this protein?
Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor.  Its binding to scaffolding polyubiquitin plays a key role in IKK activation by multiple signaling receptor pathways.  Can recognize and bind both 'Lys-63'-linked and linear polyubiquitin upon cell stimulation, with a much highr affinity for linear polyubiquitin.  Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity.  Essential for viral activation of IRF3.  Involved in TLR3- and IFIH1-mediated antiviral innate response; this function requires 'Lys-27'-linked polyubiquitination.
What are the official names of this protein?
NF-kappa-B essential modulator, NEMO, FIP-3, IkB kinase-associated protein 1, IKKAP1, Inhibitor of nuclear factor kappa-B kinase subunit gamma, I-kappa-B kinase subunit gamma, IKK-gamma, IKKG, IkB kinase subunit gamma, NF-kappa-B essential modifier.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Sumoylated NEMO accumulates in the nucleus in response to genotoxic stress.
Protein: MATK_TRIHY
Sequence: MKEYRVYLERARSRQQDFLYPLIFREYIYGLAYSHNFNRSIFVENGSYDNKYSLLNVKRLITRMSQQNHLIISANDSNKNPFLGYNKNFYSQIISEGFAIVVEIPFFLQLSSSLEEAEIIKSYKNVRSIHSIFPFLEDKFTYLNYVSDIRIPYPIHLEILVQILRYWVKDVPFFHLLRLFLYDFYNRNCFIPTKKSISTFSKSNPRLFLFLYNFYVCEYESIFLFLRNKSSHLRLKSFSVFFERIFFYAKREHLVEVFSKDFSYTLPFFKDPNIHYVRYQGKCILASKNVPFLMNKWKHYFIHLWQCFFDVWSQPRTININQLSEHSFQLLGYFSNVRLNRSVVRSQMLQNTFLIEIVSKKLDIIVPIIPLIRSLAKAKFCNVLGHPISKPVWADSSDFDIIERFLRICRNLSHYYNGSSKKKSLYRIKYILRLSCIKTLACKHKSTVRAFLKRSGSEELLEEFFTEEEEILSLIFPRDSFTLHRFHRNRIWYLDILFSNDLVNDE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: VATE_THEON
Sequence: MEGAELIIQEINREAEQKIQYILSEAQKEAEKIREEARKRAQARAEWILRKAQTQAEIEKQRIIANAKLEIRKKRLEVQEALIQEVITALRERLAELPEEEYFPMLVDLTGKAVEELGSGSVVVKSNERTLKLLEGRLDEFKKALTEKLGRDVEVTLGEPITTIGGILVETPDRTVRVDNTFESRIERFEGELRAAIAKALFG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type proton ATPase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: YR530_MIMIV
Sequence: MFNTKQQLTANKLLEFINQNTHKIFYLIGFAGSGKTYTISKITKKFLVDELIENIYYCAPTHKALKVLESYIKSNINASDKDLSNKIKFMTIHKLLEFKPIIQTETGSKVFKSTKESKFLKNISKNLVVIDECSMISQEMVDELNKYINLYPIKIIYMGDPKQLPPVGEVESLIFSTIPNNYQYHIVLDEIMRTNSVDIKAVCSVIRNWNLNDQINQKLIDVFNNSTTRRFRMYHIRNDYNKSSWFKSFIKEIQNNEVPIILTWKNSTSDYYNNIIRKFIHKSEEIDNYMINDYLMFNNYYASPENNESFFTSDMVKIIHTTTVTKILYNWSEQLISKPKTDLDRNYNSLIRKISKLDNEFKINILQVKRIQSDVVSSNNTDVHIIHVITFSDLNRYREMLKNIKEQIESFYKRFRIDTIVSKLWDIYHTKLIEPYAEINFGYSITSHKSQGSTYRSVYVDVKDICSNSNKTEMQKSLYTSAGRASERLGFMIE
What are the official names of this protein?
Uncharacterized protein R530.
Protein: PEPE_SHEAM
Sequence: MNIRALLLSASRVGDTPYLEHTLPFIAPLTEHARNWVFIPYAGISLGYDVYLEKVREGLRNLNINISGIHEHADPRQAIRDADGIFVGGGNTFHLLHELYRYDLLFVIREQVEAGKPYVGWSAGSNIAGLSIRTTNDMPIIEPPSFTALGLLPFQLNPHYTDYQAPGHNGETRAQRLLEFTMVDPLTPVVGIQEGSALYRQGDKLTLLGDKEAYFFKGSVQKSPIAAGADLSELL
What is the function of this protein?
Hydrolyzes dipeptides containing N-terminal aspartate residues.  May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.
What are the official names of this protein?
Peptidase E, Alpha-aspartyl dipeptidase, Asp-specific dipeptidase, Dipeptidase E.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_FUSNN
Sequence: MKARFDKIYKDIVDTIAEKGIWSEGNVRTKYADGTAAHYKSYIGYQFRLDNSDDEAHLITSRFAPSKAPIRELYWIWILQSNNVDVLNELGCKFWDEWKMQDGTIGKAYGYQIAQETFGQKSQLHYVINELKKNPNSRRIMTEIWIPNELSEMALTPCVHLTQWSVIGNKLYLEVRQRSCDVALGLVANVFQYSVLHKLVALECGLEPAEIIWNIHNMHIYDRHYDKLIEQVNRETFEPAKIKINNFKSIFDFKPDDIEIIDYKYGEKVSYEVAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_THENN
Sequence: MDLKQFIRDIPDFPQKGIIFRDITPLLKDSRAFREAIDRMCDLVSDRDFDLVVAPEARGFILGAAMAYKLGKGFVPVRKPGKLPYRTVYEEYQLEYGTEQLHIHEDAIERGQKVLIVDDVLATGGTAEALIRLVKKLGGEVSALAFLVELSYLNPRKRLEGYDIKTLIVY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCDGJ_PANTR
Sequence: MGGSCAQRRRAGPRQVLFPLLLPLFYPTLCEPIRYSIPEELAKGSVVGNLAKDLGLSVLDVSARELRVSAEKLHFSVDAQSGDLLVKDRIDREQICKERRRCELQLEAVVENPLNIFHIIVVIEDVNDHAPQFQKDEINLEISESVSLGMGTILESAEDPDISMNSLSKYQLSPNEYFSLVEKDNPDGGKYPELVLQKTLDRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQDVYRVSLREDVPPGTSILRVKATDQDEGINSEITYSFFGVADKAQHVFSLDYTTGNILTQQPLDFEEVERYTMNIEAKDRGSLSTRCKVIVEVVDENDNSPEIIITSLSDQIMEDSPPGVVVALFKTRDRDSGENGEVRCSLSRGVPFKIHSSSNNYYKLVTDEALDREQTPEYNVTIAATDRGKPPLSSSKTITLHITDVNDNAPVFGQSAYLVHVPENNQPGASIAQVSASDPDFGPNGRVSYSLIASDLESRTLSSYVSVSAQSGVVFAQRAFDHEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDTVPRAAQPGYLVTKVVAVDADSGHNAWLSYHVVQASEPGLFSLGLRTGEVRMVRALGDKDLVRQRLLVAVRDGGQPPLSATATLHLVFADSLQEVLPDFSDHPTPSDSQAEMQFYLVVALALISVLFLLAVILAIALRLRQSFSPTAGDCFESVLCSKSGPVGPPNYSEGTLPYAYNFCVPGDQMNPEFNFFASVDHCPATQDNLNKDSMLLASILTPSVEADKKILKQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin gamma-B7, PCDH-gamma-B7.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SHL2B_HUMAN
Sequence: MSEASRLCSGYYSLNQSFVEPFQCPRRGEGAALQYCCGFADLKYCCSEPGSYFPYKHSYMWSLSIGALIGLGIAALVLLAFVISVCVLCYLFLYTKPQRLDTGLKLQHLEASSTQEGKSNGKTKALNSNAASNATNETYYEADDIIQEKTMDATQIHIAY
What are the official names of this protein?
Protein shisa-like-2B.
What is the protein family that this protein belongs to?
Belongs to the shisa family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: BICA_SYNP2
Sequence: MQITNKIHFRNIRGDIFGGLTAAVIALPMALAFGVASGAGAEAGLWGAVLVGFFAALFGGTPTLISEPTGPMTVVMTAVIAHFTASAATPEEGLAIAFTVVMMAGVFQIIFGSLKLGKYVTMMPYTVISGFMSGIGIILVILQLAPFLGQASPGGGVIGTLQNLPTLLSNIQPGETALALGTVAIIWFMPEKFKKVIPPQLVALVLGTVIAFFVFPPEVSDLRRIGEIRAGFPELVRPSFSPVEFQRMILDAAVLGMLGCIDALLTSVVADSLTRTEHNSNKELIGQGLGNLFSGLFGGIAGAGATMGTVVNIQSGGRTALSGLVRAFVLLVVILGAASLTATIPLAVLAGIAFKVGVDIIDWSFLKRAHEISPKGALIMYGVILLTVLVDLIVAVGVGVFVANVLTIERMSNLQSEKVQTVSDADDNIRLTTTEKRWLDEGQGRVLLFQLSGPMIFGVAKAIAREHNAMGDCDALVFDIGEVPHMGVTASLALENAIEEALDKERQVYIVGAAGQTRRRLEKLKLFKRVPPDKCLMSREEALKNAVLGIYPHLADGVTAPSSEMG
What is the function of this protein?
Low/medium affinity, Na(+)-dependent bicarbonate transporter.
What are the official names of this protein?
Bicarbonate transporter BicA.
What is the protein family that this protein belongs to?
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NSP2_ROTAD
Sequence: MAELACFCYPHLENDSYKFIPFNSLAIKCMLTAKVDKKDQDKFYNSIIYGIAPPPQFKKRYNTSDNSRGMNYETTMFNKVAILICEALNSIKVTQSDIANVLSRVVSVRHLENLVLRKENHQDVLFHSKELLLKSVLIAIGQSKEIETTATAEGGEIVFQNAAFTMWKLTYLDHKLMPILDQNFIEYKITLNEDKPISDVCVKELVAELRWQYNRFAVITHGKGHYRVVKYSSVANHADRVFATYKNNTKSGNVTDFNLLDQRIIWQNWYAFTSSMKQGNTLDVCKKLLFQKIKQEKNPFKGLSTDRKMDEVSHVGI
What is the function of this protein?
Participates in replication and packaging of the viral genome.  Plays a crucial role, together with NSP5, in the formation of virus factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place.  Displays ssRNA binding, NTPase, RNA triphosphatase (RTPase) and ATP-independent helix-unwinding activities.  The unwinding activity may prepare and organize plus-strand RNAs for packaging and replication by removing interfering secondary structures.  The RTPase activity plays a role in the removal of the gamma-phosphate from the rotavirus RNA minus strands of dsRNA genome segments.
What are the official names of this protein?
Non-structural protein 2, NSP2, NCVP3, Non-structural RNA-binding protein 35, NS35.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP2 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in spherical cytoplasmic structures, called viral factories, that appear early after infection and are the site of viral replication and packaging.
Protein: RR16_COFAR
Sequence: MLKLRLKRCGRKQRAVFRIVAIDVRSRREGKDLQKVGFYDPIKNQTYLNVTAILYFLEQGAQPTGTVQDIFKKAGVFKELRPNQMKFN
What are the official names of this protein?
30S ribosomal protein S16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MNS1B_ASPTN
Sequence: MHLPSLSLPLAALTLATPSLAYPYYRTEQPLQNNLAQSRANTIKEAFSHAWDGYKKYAYPHDELHPVSNGYGDSRNGWGASAVDALSTAIIMRNATIVNQILDHIAQVDYSKTNDTVSLFETTIRYLGGMLSGYDLLKGPASGLVRDSKKVDMLLTQSKKLADVLKFAFDTPSGVPYNNININTHGNDGATSNGLAVTGTLVLEWTRLSDLTGDDEYAKLSQKAQSYLLKPQPASSEPFPGLVGSHISIETGEFTDAQVSWNGGDDSFYEYLIKMYVYDPEAFGEYKDRWEAAAQSSMEHLASHPSTRPDLTFLASYNDGKLGLSSQHLTCFDGGSFLLGGTVLDNDDYIKFGLDLVKGCHETYNATLTGIGPESFAWDPNSVPSNQKALYEKAGFYIQSGAYILRPEVIESFYYAYRITGEEQYREWIWNAFVAINKYCRTSSGFAGLQDVNAANGGGRYDNQESFLFAEVMKYVYLAHSGDAEWQVQRGNGNKFVFNTEAHPFRVR
What is the function of this protein?
Involved in the maturation of Asn-linked oligosaccharides.  Progressively trims alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2) (By similarity).
What are the official names of this protein?
Probable mannosyl-oligosaccharide alpha-1,2-mannosidase 1B, Class I alpha-mannosidase 1B, Man(9)-alpha-mannosidase 1B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 47 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle lumen.
Protein: RS3_YERPN
Sequence: MGQKVHPNGIRLGIVKAWNSTWYANTKEFADNLDSDFKVRQFLTKELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQINIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPEPAAQPKKQQRKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.