PharMolix/UniProtQA huggingface dataset:
Protein: URE2_SPOPA
Sequence: MSNNNYIVPGEYRVAEGEIEINAGREKTTIRVSNTGDRPIQVGSHIHFVEVNKELLFDRAEGIGRRLNIPSGTAARFEPGEEMEVELTELGGNREVFGISDLTNGSVDNKELILQRAKELGYKGVE
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_BORPA
Sequence: MAAKQVLFADEARVRIVRGVNVLANAVKTTLGPKGRNVVLERSFGAPTVTKDGVSVAKEIELKDKFENIGAQLVKDVASKTSDNAGDGTTTATVLAQAVVQEGLKYVAAGFNPIDLKRGIDKAVAAAVEELKKLSKPVTTSKEIAQVGSISANSDASIGQIIADAMDKVGKEGVITVEDGKSLENELDVVEGMQFDRGYLSPYFINSPEKQVAALDDPYVLIYDKKVSNIRDLLPVLEQVAKSSRPLLIIAEDVEGEALATLVVNNIRGILKTTAVKAPGFGDRRKAMLEDIAILTGGTVISEETGMSLEKATLQDLGQAKRIEVAKENTTIIDGAGDGKSIEARVKQIRAQIEEATSDYDREKLQERVAKLAGGVAVIRVGAATEVEMKEKKARVEDALHATRAAVEEGVVPGGGVALLRAKQAITGLKGDTADQNAGIKLILRAVEEPLRTIVTNAGDEASVVVNTVLNGKGNYGYNAATGEYGDLVEQGVLDPTKVTRTALQNAASVASLLLTAEAAVVELMEDKPAAAPAMPGGMGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBS_PROMM
Sequence: MPFQSTVGDYQTVATLETFGFLPPMTQDEIYDQIAYIIAQGWSPVIEHVHPSGSMQTYWSYWKLPFFGEKDLNMVVSELEACHRAYPDHHVRMVGYDAYTQSQGTAFVVFEGR
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, RuBisCO small subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Carboxysome. Note=This bacterium makes alpha-type carboxysomes.
Protein: D107A_PONPY
Sequence: MKIFFFIFAALILLAQIFQARTAIHRALICKRMEGHCEAECLTFEVKIGGCRAELAPFCCKNRKKH
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 107A, Defensin, beta 107, Defensin, beta 107A.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS13_CARHZ
Sequence: MARIAGVDLPRDKRVEIALTYIYGIGRPTANVILKKTGINPDTRVKDLTEEEVAKLRDEIEKNYKVEGELRREVALNIKRLIEIGCYRGIRHRKGLPVRGQRTRTNARTRKGPRRTVGVKRKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: HIP41_ARATH
Sequence: MAMRELSQLNRDSDGDEEVWVKHYSSNHQILLVGEGDFSFSHSLATLFGSASNICASSLDSYDVVVRKYKKARSNLKTLKRLGALLLHGVDATTLHFHPDLRYRRFDRVIFNFPHAGFHGRESDSSLIRKHRELVFGFFNGASRLLRANGEVHVSHKNKAPFSEWNLEELASRCFLVLIQRVAFEKNNYPGYENKRGDGRRCDQPFLLGECSTFKFRFSRVAKELYAEKVRSREVKERESMYPEAILNKQPVSFDHRYRLQTEFEAIAGTITLGKSKILWLSQEKGHLHWIFVTTKNVDVYSSKIPVFLICTLESRQRDIACFVKTFQFKLVKNHYPNTLTAGVEFLVKFITGKYEECQQVTYLRKNFSGYGDGNKQRIVLKMDMSDEKSMKKAMKIASAKPGVRSVSIQGQNDQLVLLGEGIDLAELTRELKKKVCMTTIITVQAAPPQQPPQPHPMGQYNQMPPARRCTCEIPNSGFCGFCRSMSQPNYQVVPSPYYPPMLYCRDETDGCRIL
What is the function of this protein?
Heavy-metal-binding protein.
What are the official names of this protein?
Heavy metal-associated isoprenylated plant protein 41, AtHIP41.
What is the protein family that this protein belongs to?
Belongs to the HIPP family.
Protein: A1HA_LOXIN
Sequence: MLPYIVLVLGCWSVLSQAAQTDDEERAGNRRPIWIMGHMVNAIGQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRNCKKYENFNDFLKGLRSATTPGNSKYQEKLVLVVFDLKTGSLYDNQANDAGKKLAKNLLQHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFKDQLTKDGHPELMDKVGHDFSGNDDIGDVGKAYKKAGITGHIWQSDGITNCLPRGLSRVNAAVANRDSANGFINKVYYWTVDKRSTTRDALDAGVDGIMTNYPDVITDVLNEAAYKKKFRVATYDENPWVTFKK
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) with high activity (PubMed:16581177, PubMed:9790962, PubMed:21590705, PubMed:27233517).  It also acts on lysophosphatidylcholine (LPC), and lyso-platelet activating factor (LPAF, an alkyl-LPC) but not on phosphatidylcholine (PC) (PubMed:21590705, PubMed:27233517).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  In vivo, it induces dermonecrosis, vascular permeability, platelet aggregation, inflammatory response, edema and cytotoxicity against renal epithelial cells (PubMed:16581177, PubMed:9790962, PubMed:17900646, PubMed:27233517).  It causes direct nephrotoxicity (PubMed:16005484) and is directly toxic to liver (PubMed:18765244).  It also induces hemolysis in a complement-dependent manner as well as in a complement-independent manner (PubMed:9790962, PubMed:17900646, PubMed:21590705, PubMed:27233517).  The hemolysis provoked in a complement-independent manner is composed of several steps (PubMed:21590705).  The toxin binds to erythrocyte membranes, hydrolyzes membrane phospholipids (SM and LPC) thus generating metabolism products that cause hemolysis, probably by provoking an increase of calcium inside cells (PubMed:21590705).  The calcium influx is due to the opening of L-type calcium channels, since L-type calcium channel blockers inhibit calcium influx (PubMed:21590705).  In vivo, is lethal to mice when intraperitoneally injected (PubMed:17900646).
What are the official names of this protein?
Dermonecrotic toxin LiSicTox-alphaIA1a, Dermonecrotic toxin 1, DT1, LiRecDT1, P1, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D 1, SMD 1, SMase D 1, Sphingomyelinase D 1.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily. Class IIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOC_MYCUA
Sequence: MSSPDQNPSDAAGQTGSSNEEVVDVRRGMFGVKGSGDTSGYGRLVREIVLPGSSPRPYGFYFDEIADRLAEALNRDGVEFEDAIEKVVVYRNELTLHVRREALLRVAQSLRDEPELRFELCLGVNGVHYPHETGRELHAVYPLQSITHNRRLRLEVSAPDSDPHIPSLYAVYPTNDWHERETYDFFGIIFDGHPSLTRIEMPDDWQGHPQRKDYPLGGIPVEYKGAQIPPPDERRGYN
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL29_FINM2
Sequence: MKTKEIRNLSDQDLQKQLEQSKSELFNLRFQLATGQLENPMMIGLVKKDIARIKTIIRERELNIGKEA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: DDL_CHLT3
Sequence: MNKKKVALLFGGRSSEHEISVISARSIANALDKTKYKIQPIYITKAGKWLGAEASRKILAMDFESAIKSPTKKEIHLIEKEIVLLCQNSQFRFDFRTAKIDVAFPVLHGPYGEDGTVQGLLEMFDVAYVGSGVLASAITMDKAVAKICFEHAGLQVGEYLAFLRREFEENRGSVVARAEKKLRYPMFVKPANMGSSVGISKAHNRNELIEAIELALAYDRKFLIEKAINAREMEVAVLGNDEPIASAVGEVVPCNEFYDYDAKYVKGSSEVIIPAQISEAFAGKLKAAALNAFVAADCEGMARVDFLVEKETNEIYINEINSIPGFTSISMYPKLFAQVGISYTELINRLIELALERYSERKLRKI
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDB4U_TITSE
Sequence: FGVLNFF
What are the official names of this protein?
Venom peptide 6.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short antimicrobial peptide (group 4) family.
What are the subcellular locations of this protein?
Secreted.
Protein: MUR2_ENTHA
Sequence: MENIARKERRRLNETKRFRKVKRSAALVGTAMVGCSVAAPLIQPVQVDADQTPTQFGARINTAAFIAEIATYAQPIAQANDLYASVMIAQAVVESGWGSSALSQAPYYNLFGIKGSYQGQTVYMDTLEYLNNKWVSKKEPFRQYPSFAESFNDNAYVLRNTSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIITTYGLTKYDTPASGNAGGGVTIGNGGNTGNTSNSGSTSGNSGGSATTTGTTYTVKSGDSVWGISHSFGITMAQLIEWNNIKNNFIYPGQKLTIKGGQSAGSSTTNTGNNASSGNTSGNTNTSGSTGQATGAKYTVKSGDSVWKIANDHGISMNQLIEWNNIKNNFVYPGQQLVVSKGSSSASGSTSNTSTGNTSSNTANTGSTTSGSTYTVKAGESVWSVSNKFGISMNQLIQWNNIKNNFIYPGQKLIVKGGSSSSNASTSTANNKNTASSNTSSTATGQATYTVKAGESVWGVANKNGISMNQLIEWNNIKNNFIYPGQKLIVKGGSSKASATATIKPTASTPASTTPTASSTGDTKYTVKAGESVWGVANKHHITMDQLIEWNNIKNNFIYPGQEVIVKKGTAQSTPAKSDEKTYTVKAGESVWGVADSHGITMNQLIEWNNIKNNFIYPGQQLIVKK
What is the function of this protein?
May work in concert with and potentiate the processive hydrolytic action of muramidase-1, which requires binding of the enzyme to non-reducing ends of glycan chains.  Hydrolysis in the midst of glycan chains would increase the number of binding sites for muramidase-1.  May function in facilitating septum formation and cell separation.  Active on M. luteus cell walls and on E. hirae cell wall fractions, but not active on E. hirae intact cell walls.  Can covalently bind penicillin.
What are the official names of this protein?
Muramidase-2, 1,4-beta-N-acetylmuramoylhydrolase, Lysozyme, Peptidoglycan hydrolase, Pg-hydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 73 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PEPX_STRPN
Sequence: MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRFFFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDVFRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLATFSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKASDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDYFLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVKADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGGYPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYLLNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSIDFRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQAIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSSTNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKGYLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNTDYHLTVDLAQSMLTLPC
What is the function of this protein?
Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
What are the official names of this protein?
Xaa-Pro dipeptidyl-peptidase, X-Pro dipeptidyl-peptidase, X-prolyl-dipeptidyl aminopeptidase, X-PDAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CREA_CONVL
Sequence: MGFRVLVLVVMATTSALPFTFSEEPGRSPFRPALRSEEAQALRHGLTLLLARRADGQPPDMRQPEMRRPEMRRPEVRQPEFAETPVGQKRGGLGRCIYNCMNSGGGLSFIQCKTMCY
What are the official names of this protein?
Conotoxin vil14a, Conotoxin vil14.1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin R superfamily.
Protein: 3MGH_STAAE
Sequence: MDFVNNDTRQIAKNLLGVKVIYQDTTQTYTGYIVETEAYLGLNDRAAHGYGGKITPKVTSLYKRGGTIYAHVMHTHLLINFVTKSEGIPEGVLIRAIEPEEGLSAMFRNRGKKGYEVTNGPGKWTKAFNIPRAIDGATLNDCRLSIDTKNRKYPKDIIASPRIGIPNKGDWTHKSLRYTVKGNPFVSRMRKSDCMFPEDTWK
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: MKNK2_MOUSE
Sequence: MVQKRTAELQGFHRSFKGQNPFELAFSLDLAQHRDSDFSPQCEARPDMPSSQPIDIPDAKKRGRKKKRCRATDSFSGRFEDVYQLQEDVLGEGAHARVQTCVNLITNQEYAVKIIEKQLGHIRSRVFREVEMLYQCQGHRNVLELIEFFEEEDRFYLVFEKMRGGSILSHIHRRRHFNELEASVVVQDVASALDFLHNKGIAHRDLKPENILCEHPNQVSPVKICDFDLGSGIKLNGDCSPISTPELLTPCGSAEYMAPEVVEAFSEEASIYDKRCDLWSLGVILYILLSGYPPFVGHCGSDCGWDRGEACPACQNMLFESIQEGKYEFPDKDWSHISFAAKDLISKLLVRDAKQRLSAAQVLQHPWVQGCAPENTLPTPLVLQRNSCAKDLTSFAAEAIAMNRQLAQCEEDAGQDQPVVIRATSRCLQLSPPSQSKLAQRRQRASLSATPVVLVGDRA
What is the function of this protein?
Serine/threonine-protein kinase that phosphorylates SFPQ/PSF, HNRNPA1 and EIF4E.  May play a role in the response to environmental stress and cytokines.  Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.  Required for mediating PP2A-inhibition-induced EIF4E phosphorylation.  Triggers EIF4E shuttling from cytoplasm to nucleus.  Enhances the formation of EIF4F complex in pachytene spermatocytes, thus promoting mRNA translation during spermatogenesis.  Displays a high basal kinase activity.  Acts as a mediator of the suppressive effects of IFNgamma on hematopoiesis.  Negative regulator for signals that control generation of arsenic trioxide As(2)O(3)-dependent apoptosis and anti-leukemic responses.  Involved in anti-apoptotic signaling in response to serum withdrawal.
What are the official names of this protein?
MAP kinase-interacting serine/threonine-protein kinase 2, MAP kinase signal-integrating kinase 2, MAPK signal-integrating kinase 2, Mnk2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, PML body.
Protein: HLDE_ECO81
Sequence: MKVTLPEFERAGVMVVGDVMLDRYWYGPTSRISPEAPVPVVKVNTIEERPGGAANVAMNIASLGANARLVGLTGIDDAARALSKSLADVNVKCDFVSVPTHPTITKLRVLSRNQQLIRLDFEEGFEGVDPQPLHERINQALSSIGALVLSDYAKGALASVQQMIQLARKAGVPVLIDPKGTDFERYRGATLLTPNLSEFEAVVGKCKTEEEIVERGMKLIADYELSALLVTRSEQGMSLLQPGKAPLHMPTQAQEVYDVTGAGDTVIGVLAATLAAGNSLEEACFFANAAAGVVVGKLGTSTVSPIELENAVRGRADTGFGVMTEEELKLAVAAARKRGEKVVMTNGVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGDSRPVNPLEQRMIVLGALEAVDWVVSFEEDTPQRLIAGILPDLLVKGGDYKPEEIAGSKEVWANGGEVLVLNFEDGCSTTNIIKKIQLDKKG
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: CHLL_PROMS
Sequence: MTSTINRPLDGEGSVQVKQDPKINIEEGALVIAVYGKGGIGKSTTSSNLSAAFSKLGKKVLQIGCDPKHDSTFTLTHKMVPTVIDILEEVDFHSEELRPTDFMFEGFNGVMCVESGGPPAGTGCGGYVTGQTVKLLKEHHLLEDTDVVIFDVLGDVVCGGFAAPLQHANYCLIVTANDFDSIFAMNRIVSAIKAKAKNYKVRLGGVVANRSKDTDQIDKFNERTGLKTMAHFKDVDAIRRSRLKKCTIFEMEPTEDVIEVQNEYLSLAKNMLENVEPLEGNPLKDREIFDLLGFD
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: Y1810_SYNJA
Sequence: MQRLQRGLVLLLWAGLGILAITALASFYVDLAWFAELNALPVLWTRVLARWGLGLGAFAFALAVVGSNIRACWRGASTAGAWAIALGLSGGLAWSLSQHWFALLLWLHQVPVGESDPIFGRDLGFFLFGLPFWETLQQWCFNLVLLTLITVALIYLVELGLSEQRLTLALSLFAQRHLLILGGALFLLRAWGHWLERYELLYSTRGVVFGAGFADVHATLPATTLMSGVAFLTAVGFWALARQGIRFNLPLFKSWCPAWASSLLAPALLWGAYLGFGLLTTRLYPQLLQTLLVTPNELELERPYIEHNIRFTRAGFGLAEVEVKPFPEEGSLTWEILQQNQSTLRNVRLWDTEPLLATYRQLQEIRPYYQFPYVDVDRYRIGGELRQVMHAARELDFAQVPPAAQTWVNRRFFYTHGYGLTLSPVNVVTAEGLPDFFLSDIPPRVSPRYPEVAQVLRVEQPALYYSELTTTDVFVGAEARELDYPAADRYVYSSYRGTGGVPIPHLWQRLLYAWHFRDLRILLSRELSPSTRFLYRRQIRERVRQVMPFLLYDQDPYLVIQGGRLYWFFDAYTTSSRYPYSEHLPGFPFNYIRNSVKAVLDAYNGSIDWYIADPRDPLIQAYARIYPTLFKPLEAMPEPLRQHIRYPQDLFRVQVQQFATYHMTDPRVFYNREDQWQIPNQFRKRRRLPMQPQYLILTLPEDPQKGSPNQPEFVLLSPFTPLNKQNMVAWMAARCDGENYGKLLVYEFSKQRLIYGPEQVEARVNQDPAISEQIALWNEHGSRVNLGTLLVIPIETSLLYIQPLYLEAEQGRLPQLTRVIAAYEDRVVMEPTLSQALEALFSPTGSRRSNR
What are the official names of this protein?
UPF0182 protein CYA_1810.
What is the protein family that this protein belongs to?
Belongs to the UPF0182 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MUTS_YERPP
Sequence: MKNNDKLDSHTPMMQQYLRLKAQHPEILLFYRMGDFYELFYSDAKRASQLLDISLTKRGASAGEPIPMAGVPYHSIENYLAKLVQLGESAAICEQIGDPATSKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDAKGFGYATLDISSGRFRVAEPADLETMAAELQRTNPAELLYPENFEPMSLIEHRHGLRRRPLWEFELDTAKQQLNLQFGTRDLIGFGVEQAHLALRAAGCLLQYVKDTQRTSLPHIRGLTMERQQDGIIMDAATRRNLELTQNLSGGSENTLAAILDCSVTPMGSRMLKRWLHMPIRDIRVLTDRQQAIGGLQDIAAELQTPLRQVGDLERILARLALRTARPRDLARMRHAFQQLPEIHRLLQPIDVPHVQNLLSQVGQFDELQDLLERAIVETPPVLVRDGGVIASGYNAELDEWRALADGATDYLDRLEIREREKLGLDTLKVGFNGVHGYYIQVSRGQSHLVPIHYVRRQTLKNAERYIIPELKEYEDKVLTSKGKALAIEKGLYEEIFDLLLPHLPELQLSANALAELDVLANLAERAETLNYSCPTLSDKPGIKIMGGRHPVVEQVLKEPFISNPLTLSPQRRMLIITGPNMGGKSTYMRQTALIVLLAHLGSYVPADQATIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATEQSLVLMDEIGRGTSTYDGLSLAWACAENLASRIKAMTLFATHYFELTTLPEKMEGVVNVHLDALEHGETIAFMHSVQEGAASKSYGLAVAALAGVPRDVIKRARQKLKELESLSNNAAASTIDGSQMTLLNEEIPPAVEALEALDPDSLSPRQALEWIYRLKNMV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: ANM3_HUMAN
Sequence: MCSLASGATGGRGAVENEEDLPELSDSGDEAAWEDEDDADLPHGKQQTPCLFCNRLFTSAEETFSHCKSEHQFNIDSMVHKHGLEFYGYIKLINFIRLKNPTVEYMNSIYNPVPWEKEEYLKPVLEDDLLLQFDVEDLYEPVSVPFSYPNGLSENTSVVEKLKHMEARALSAEAALARAREDLQKMKQFAQDFVMHTDVRTCSSSTSVIADLQEDEDGVYFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISEWMGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDVYGFKMSCMKKAVIPEAVVEVLDPKTLISEPCGIKHIDCHTTSISDLEFSSDFTLKITRTSMCTAIAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEALKGKVTVHKNKKDPRSLTVTLTLNNSTQTYGLQ
What is the function of this protein?
Protein-arginine N-methyltransferase that catalyzes both the monomethylation and asymmetric dimethylation of the guanidino nitrogens of arginine residues in target proteins, and therefore falls into the group of type I methyltransferases (Probable).  May regulate retinoic acid synthesis and signaling by inhibiting ALDH1A1 retinal dehydrogenase activity (PubMed:33495566).
What are the official names of this protein?
Protein arginine N-methyltransferase 3, Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNZ_STRP8
Sequence: MELQFLGTGAGQPAKQRNVSSLALKLLDEINEVWMFDCGEGTQRQILETTIKPRKIRKIFITHLHGDHIFGLPGFLSSRSFQASEEQTDLDIYGPIGIKTYVLTSLKVSGARVPYQIHFHEFDDKSLGKIMETDKFVVYAERLAHTIFCMGYRVVQKDLEGTLDAEALKAAGVPFGPLFGKIKNGQDVELEDGRLICAKDYISAPKKGKIITIIGDTRKTSASVKLAKDADVLVHESTYGKGDERIARNHGHSTNMQAAQIAHEAGAKRLLLNHVSARFLGRDCRQMEKDAATIFENVKMVQDLEEVII
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: HYPA_SHEB8
Sequence: MHEYSIVSALIEQCEQHALANHAAKITRVDIKLGVMSGVEPSLLQTAFDTFKLDSICKAAQLNIQIQPLVILCQDCQSESVLSERTVVCPTCQSYRTRVLDGEDMLLMQLEMEQDED
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: ZDH12_HUMAN
Sequence: MAPWALLSPGVLVRTGHTVLTWGITLVLFLHDTELRQWEEQGELLLPLTFLLLVLGSLLLYLAVSLMDPGYVNVQPQPQEELKEEQTAMVPPAIPLRRCRYCLVLQPLRARHCRECRRCVRRYDHHCPWMENCVGERNHPLFVVYLALQLVVLLWGLYLAWSGLRFFQPWGQWLRSSGLLFATFLLLSLFSLVASLLLVSHLYLVASNTTTWEFISSHRIAYLRQRPSNPFDRGLTRNLAHFFCGWPSGSWETLWAEEEEEGSSPAV
What is the function of this protein?
Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates (PubMed:36586411).  Has a palmitoyltransferase activity toward gephyrin/GPHN, regulating its clustering at synapses and its function in gamma-aminobutyric acid receptor clustering (By similarity).  Thereby, indirectly regulates GABAergic synaptic transmission (By similarity).  Acts as an inhibitor of the NLRP3 inflammasome by mediating palmitoylation of NLRP3, thereby promoting NLRP3 degradation by the chaperone-mediated autophagy (CMA) process (PubMed:36586411).
What are the official names of this protein?
Palmitoyltransferase ZDHHC12, DHHC domain-containing cysteine-rich protein 12, DHHC-12, Zinc finger DHHC domain-containing protein 12, Zinc finger protein 400.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.