PharMolix/UniProtQA huggingface dataset:
Protein: IL10_PANTR
Sequence: MHSSALLCCLVLLTGVRASPGQGTQSENSCTHFPGNLPNMLRDLRDAFSRVKTFFQMKDQLDNLLLKESLLEDFKGYLGCQALXEMIQFYLEEVMPQAENQDPDIKVHVNSLGENLKTLRLRLRRCHRFLPCENKSKAVEQVKNAFNKLQEKGIYKAMSEFDIFINYIEAYMTMKIRN
What is the function of this protein?
Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation.  Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3.  In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators.  Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines including granulocyte-macrophage colony-stimulating factor /GM-CSF, granulocyte colony-stimulating factor/G-CSF, IL-1 alpha, IL-1 beta, IL-6, IL-8 and TNF-alpha.  Interferes also with antigen presentation by reducing the expression of MHC-class II and co-stimulatory molecules, thereby inhibiting their ability to induce T cell activation (By similarity).  In addition, controls the inflammatory response of macrophages by reprogramming essential metabolic pathways including mTOR signaling (By similarity).
What are the official names of this protein?
Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF.
What is the protein family that this protein belongs to?
Belongs to the IL-10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GATB_NOVAD
Sequence: MSEYRIQGATGEWEVVIGLEVHAQVTSNAKLFSGAATAFGAEPNTQVSLVDAAMPGMLPVPNRECIRQAVRTGMAINAQINKWSRFDRKNYFYADLPQGYQISQLYHPIVGEGSIEVQLDDKNPESLKTIGIERIHVEQDAGKLMHDQHPTMSYVDLNRSGVALMEIVSRPDMRSPAEAGAYLSKLRTILRYVGSCDGNMDQGSMRADVNVSVRRPGEPFGTRTETKNVNSVRFVMAVVEQEAKRQVALIEDGGTVVQETRLYDPDRNETRSMRSKEDAHDYRYFPDPDLLPLELDDAFLEECRASLPELPDAKRHRYETALGLSAYNAGVLTADVETARWFEALLAETAAKAKKPEAEVAKQAANWLISELFGALNKLGASLETSPVTPAAGAELLALIADGTISGSIAKQVLEKMLETGDGAAAIVEREGLKQTSDTGAIEAAIDGILAANADKVGQYKAGKEALFGFFVGQTMKAMQGKANPGVVNELLRKKLG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: RPO10_HALS3
Sequence: MMVPVRCFSCGTVVGEHWEAFKARAETHDGDEDPADVLDDLGVDRHCCRRMLIAHQDLVDVVSPYQ
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo10, DNA-directed RNA polymerase subunit N.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XPT_LARHH
Sequence: METLKRKIIDEGRLLDGHILKVDNFLNHQIDVRLMNDIGQAFAERFAGTRIDKILTIEASGIAVAAIASQYFGFVPVVFGKKTQSLNLDAEAFESEVYSYTKQTSYKVRVSKRYLRPGEQVLIIDDFLANGAAASGLIDIVRQAGAEPVGVGIVIEKGFQPGRSKIEAHGIRVESLAIIQSFDDNQVHFG
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_CITBB
Sequence: MSAVRENGVIVAIDGPSGAGKSSLTKLLAKRLGYIHIDTGAMFRAVALSAQRAGIKSDDDAGLAELCRGLEIAFARDGETCRVLANGEDVSTKIRTEEIGLLTSTISARKPVRQALLEMQRKMGAKGGVILEGRDIGTVVFPDAEVKFFLSASAEERGRRRYLELAARGESATLEETIAKVIQRDRQDEGREHAPLKQAQDAVPIDSTSLTIEQVLELMESTVKERLAQGDKG
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NGG1_YEAST
Sequence: MPRHGRRGKLPKGEKLPKKEGGDNTPSKLLSSMLKTLDLTFERDIGMLNGKSVRSIPNKKTLLELQSQLDSLNEILGTIARGDQETIEALRKIRDSKNEKQANDEKQETSNADGQHESSTATEETNIIDKGVQSPPKPPPSNEISGTIENDVESIKQAADNMAKEEINEDKDLQVHRDQPREKRPFDSETENRATENENTQRPDNKKQKIDVDKMENDPTVKNPKSEFVVSQTLPRAAAALGLFNEEGLESTGEDFLKKKYNVASYPTNDLKDLLPGELPDMDFSHPKPTNQIQFNTFLAFVENFFKDLSDDNLKFLKMKYIIPDSLQFDKTYDPEVNPFIIPKLGPLYTDVWFKDENDKNSAYKKPSPYSNDASTILPKKSANELDDNALESGSISCGPLLSRLLSAVLKDDNDKSELQSSKIIRDGGLPRTGGEDDIQSFRNNNNDTVDMTLSQENGPSVQTPDNDIDEEASFQAKLAENKGSNGGTTSTLPQQIGWITNGINLDYPTFEERLKRELKYVGIYMNLPKDENNPNSDDPDWVTGREDDEISAELRELQGTLKQVTKKNQKRKAQLIPLVERQLAWQEYSSILEDLDKQIDQAYVKRIRVPKKRKKHHTAASNNVNTGTTSQIAQQKAANSSLKSLLDKRQRWINKIGPLFDKPEIMKRIPNESVFKDMDQEEDEDEADVFAQNTNKDVELN
What is the function of this protein?
Transcription regulator.  Could inhibit GAL4 DNA-binding or its ability to activate transcription.  Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA, SLIK and ADA.  SAGA is involved in RNA polymerase II-dependent transcriptional regulation of approximately 10% of yeast genes.  At the promoters, SAGA is required for recruitment of the basal transcription machinery.  It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (SPT3, SPT8 and SPT20) and promoter selectivity, interaction with transcription activators (GCN5, ADA2, ADA3 and TRA1), and chromatin modification through histone acetylation (GCN5) and deubiquitination (UBP8).  SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac).  SAGA interacts with DNA via upstream activating sequences (UASs).  SALSA, an altered form of SAGA, may be involved in positive transcriptional regulation.  SLIK is proposed to have partly overlapping functions with SAGA.  It preferentially acetylates methylated histone H3, at least after activation at the GAL1-10 locus.  ADA preferentially acetylates nucleosomal histones H3 (at 'Lys-14' and 'Lys-18') and H2B.
What are the official names of this protein?
Chromatin-remodeling complexes subunit NGG1, Transcriptional adapter 3.
What is the protein family that this protein belongs to?
Belongs to the NGG1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: XYLA_NOVAD
Sequence: MSADYFADFQTVRYEGPDSDNDFAYRWYDKDRVILGKRMEDHLRFAVCMWHTFCWPGSDVFGAGTFTRPWLQGPMDARNAAAKREAALAFVEKLDVPFYCFHDVDVMAEAEGIGEFRSSFAEAVDHLEELQGKHGRKLLWGTANLFGHPRYMAGAATNPDPEVFAWGASQVRDALEATHRLGGANYVLWGGREGYDSILNTEIGIEQENFGRFLSLVVDHKHRIGFKGTILIEPKPHEPTKHQYDFDTQTVFGFLKRFGLESEVKVNIEANHATLSGHTFEHELAMARALGILGSIDANRGDHQNGWDTDQFPNSVEELTLAMLELIRAGGFTDGGFNFDAKVRRQSIDAADLFHGHIGGIDTIAHALVKAAALIEDGKLDAFRAERYAGWQGELGRKIHADGTTLADIADIAVARDLAPVRRSGRQEWCENLINRV
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPKA_HUMAN
Sequence: MTDVETTYADFIASGRTGRRNAIHDILVSSASGNSNELALKLAGLDINKTEGEEDAQRSSTEQSGEAQGEAAKSES
What is the function of this protein?
Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.
What are the official names of this protein?
cAMP-dependent protein kinase inhibitor alpha, PKI-alpha, cAMP-dependent protein kinase inhibitor, muscle/brain isoform.
What is the protein family that this protein belongs to?
Belongs to the PKI family.
Protein: TRYI_DROME
Sequence: MAVYGIVATVLVLLLLGDASDVEATGRIIGGSDQLIRNAPWQVSIQISARHECGGVIYSKEIIITAGHCLHERSVTLMKVRVGAQNHNYGGTLVPVAAYKVHEQFDSRFLHYDIAVLRLSTPLTFGLSTRAINLASTSPSGGTTVTVTGWGHTDNGALSDSLQKAQLQIIDRGECASQKFGYGADFVGEETICAASTDADACTGDSGGPLVASSQLVGIVSWGYRCADDNYPGVYADVAILRPWIVKAANAI
What are the official names of this protein?
Trypsin iota.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: TRMD_HALH5
Sequence: MKIDFLTLFPEMFQGVLHSSILKQAQERGAVSFRVVNFREYSENKHKKVDDYPYGGGAGMVLSPQPLFDAVEDLTKKSSSTPRVILMCPQGETFTQRKAEELAQAEHLILLCGHYEGYDERIRSYLVTDELSIGDYVLTGGELGAMVIADSVTRLLPAVLGNETSAQTDSFSTGLLEYPQYTRPADFRGWKVPDVLLSGHHQNIERWRKEQSLKRTLERRPDLLEGRKLTEEEQELLDSIRKQQEK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
Protein: EPIC1_PHYIT
Sequence: MTFLRPILALLAATALVTTSAQVDGGYSKKEVTPEDMELLQKAQSNVSAYNSDVTSRICYLKVDSLETQVVSGENYKFHVSGCSVNSDNELGGCANQNCESSKYDIVIYSQSWTNTLEVTSITPVK
What is the function of this protein?
Secreted effector that interacts with and inhibits the pathogenesis-related papain-like cysteine proteases C147 and RCR3 of host plants (PubMed:17085509, PubMed:19171904, PubMed:20940351).  Inhibition of host proteases by a pathogen extracellular protease inhibitor forms a specific type of defense-counterdefense mechanism between plants and microbial pathogens (PubMed:17085509, PubMed:19171904, PubMed:20940351).
What are the official names of this protein?
Cystatin-like cysteine protease inhibitor EPIC1, Extracellular protease inhibitor with cystatin-like domain protein 1, Secreted effector EPIC1.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted. Note=Localizes to host apoplast where it targets defense proteases for inhibition.
Protein: ULAR_ECOLU
Sequence: MTEAQRHQILLEMLAQLGFVTVEKVVERLGISPATARRDINKLDESGKLKKVRNGAEAITQQRPRWTPMNLHQAQNHDEKVRIAKAASQLVNPGESVVINCGSTAFLLGREMCGKPVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQSITLSPQGSENSLYAGHWMFTSGKGLTAEGLYKTDMLTAMAEQKMLSVVGKLVVLVDSSKIGERAGMLFSRADQIDMLITGKNANPEILQQLEAQGVSILRV
What is the function of this protein?
Represses ulaG and the ulaABCDEF operon.
What are the official names of this protein?
HTH-type transcriptional regulator UlaR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MENC_ECOBW
Sequence: MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLREGEREGWGEISPLPGFSQETWEEAQSVLLAWVNNWLAGDCELPQMPSVAFGVSCALAELTDTLPQAANYRAAPLCNGDPDDLILKLADMPGEKVAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRLDANRAWTPLKGQQFAKYVNPDYRDRIAFLEEPCKTRDDSRAFARETGIAIAWDESLREPDFAFVAEEGVRAVVIKPTLTGSLEKVREQVQAAHALGLTAVISSSIESSLGLTQLARIAAWLTPDTIPGLDTLDLMQAQQVRRWPGSTLPVVEVDALERLL
What is the function of this protein?
Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
What are the official names of this protein?
o-succinylbenzoate synthase, OSB synthase, OSBS, 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase, o-succinylbenzoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
Protein: PCP_THEPX
Sequence: MKILVTAFDPFGGENINPSYEVLKNLKDNIEGAEIIKIQVPTVFYLSVEKVIEKIKEVKPDAVLSIGQAGGRYDITVERIAINIDDARIPDNIGQQPIDTPIDPEGAPAYFATIPIKEIVEEIKKENIPASISNTAGTFVCNHLMYGILNYVHKNGLNIKAGFIHIPYLPVQVLNKPYTPSMSLGDMVKAIETAIKVIAKKSR
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y226_SHELP
Sequence: MTSAEHLTKGQQAEDRALAYLEQQGLKLVERNVRYPFGEIDLIMRQGHKWIFIEVKYRQSKQFGGALQAVSRGKIARLNRAASHYMQLNQIDAQCRFDLLAIDGDDIQWITNAF
What are the official names of this protein?
UPF0102 protein Shew_0226.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: Y211_MYCGE
Sequence: MDNKNPQKLITSELLANHRFNFAKDDKGGYDANEVDAFLDQLTKTLIHYEEMKNNEQELKNAYDKLFSDRDQILSRCAKLEADLNTFYENGYANKVLINRVQELEDKLEKLPDRYTEKLERIEKLLKKVIKHWTDGEDISNFEDEFF
What are the official names of this protein?
Uncharacterized protein MG211.
Protein: RS21_DICDI
Sequence: MDSKNVELYTPRKCSATNRLITAKDHASVQINIGHVNAEGIYNGEQTIFAFCGFLRNNGQSDAALNRLAQQKGFLKSF
What are the official names of this protein?
40S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS21 family.
Protein: U375B_CAEEL
Sequence: MNSFVSTVLLLSVTIALVSGYPSQLQTTCVTKAKSCTMFFLNGVYCTECTYSGTLELKIGSTCTFSIYEKKVASQPNENSQNEVAQCKQSSCYSNQFVPVDCAAAFGNEYITYIENQ
What are the official names of this protein?
UPF0375 protein C08F11.12.
What is the protein family that this protein belongs to?
Belongs to the UPF0375 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSD_BLOFL
Sequence: MLEKIQVILQYLLPIRWITYLAGLGASWKGGWITRYIILLFIRIYKINLQECIDPNINNYKTFNEFFMRKFNINTRSIDKNPSTLIIPADGIISQIGKINNTHIFQIKNSSYYLDQLLAGHDNIINYFRNGSFVIIYIPPQNCHWVYMPCTGTLRELLYIPGDLFSVHPKIIKNIPDVLSRNEKLICLFDTQFGYMAQILVGSAIVGSIETVWCGTITPPRTGLVKHWHYPKSYNNNITTKSTERNAVILSKAAEMGVFKFGSTVINLFSNDTVLLNEKLQLNNIVKIGMTLAHGKIN
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GCSH_CITK8
Sequence: MSNVPVELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVDLPDVGATVAAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWIFKIKASDESEIDSLLDATAYEALLEDE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: TRUA_HELPH
Sequence: MRCFKATIAYDGAYFLGYAKQPNKLGVQDKIENALNTLGIKSVVVAAGRTDKGVHANNQVLSFHAPKHWNVAKLFYYLAPKLAPHIVLKKLEEKNFHARFDAQKRAYRYLLTKNLKTPFLAPYIACGDYGSLDLLNSALKQFTGKHDFSLFKKEGGATTNPNRIIFNAFAYTAFIMGHECVVFKIIGDAFLRSSVRLIIQTCVQYSLEKITLAEIEMQIHNIKATIRTPIMADGLYLHRVYY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RL22_NATPD
Sequence: MGISYSVDVDPDETAKAMLRERHMSHKHSKEIAREIKGKTAGEAVDYLEAVIDGDRSVPFKSHNTGVGHRNDIEGWDAGRYPEKASEAFLDLLENGINNADHQGFEGEEMVIEHVAAHKVGESPGQKPRAFGRASPWNTPQVDVELVLRTEDDE
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: TUSA_SHEB5
Sequence: MNDAFSTAQHRLDALGLRCPEPVMMVRKTVRQMAAGETLLIIADDPATTRDIPSFCEFMDHTLIASETTQTPYQYLIKKGL
What is the function of this protein?
Sulfur carrier protein which probably makes part of a sulfur-relay system.
What are the official names of this protein?
Sulfur carrier protein TusA.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NR1H2_BOVIN
Sequence: MSTPTTNSVDTPLPGNGPSTPSSSPGGKEDGPEPCPGGADPDVPSTDGADSASVVVILDTAEEPERKRKKGPAPKMLGDELCQVCGDTASGFHYNVLSCEGCKGFFRRSVIRGGAGRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSKEQIRKKKIRKQQQQQQQQSSPTGPGVSSSSPASGPGASPGGSDGGGQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPSRVEALQQPYVDALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
What is the function of this protein?
Nuclear receptor that exhibits a ligand-dependent transcriptional activation activity (By similarity).  Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4).  Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8; DLDLR and LRP8.  Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity).  Induces LPCAT3-dependent phospholipid remodeling in endoplasmic reticulum (ER) membranes of hepatocytes, driving SREBF1 processing and lipogenesis (By similarity).  Via LPCAT3, triggers the incorporation of arachidonate into phosphatidylcholines of ER membranes, increasing membrane dynamics and enabling triacylglycerols transfer to nascent very low-density lipoprotein (VLDL) particles.  Via LPCAT3 also counteracts lipid-induced ER stress response and inflammation, likely by modulating SRC kinase membrane compartmentalization and limiting the synthesis of lipid inflammatory mediators (By similarity).  Plays an anti-inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex (By similarity).
What are the official names of this protein?
Oxysterols receptor LXR-beta, Liver X receptor beta, Nuclear receptor subfamily 1 group H member 2.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARGC_ACIBY
Sequence: MISVGIVGGTGYTGVELLRILLRHPKAQVRVLTSRTEAGKPVADMFPNLRGHTDLQFSDLNIDALKECDVVFFATPHGVAMQHAKDLIAAGTKVIDLAADFRLQNLEQFEKWYGMEHACPDVLKDSVYGLTELNREKIKQAQVIGNPGCYPTTVQLGLAPLLKSAQALIETKNIIIDAKSGVSGAGRKASLGMIYSENADNFKAYGVAGHRHHPEIVEALENIAGKKDVFEGLLFVPHLVPMIRGMLSTIYVDLTEAGKQTALQALYENFYANEKFVDVMPANSSPETRSVRGANELRIALYKPQPNKLIILAAQDNLVKGASGQAVQNMNLMFGFNEDEGLQGIGLLP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RT25_ASPTN
Sequence: MGKYNLTALRVRQTALSQKAAGKIKRLPQWVDVIGDIPPAQVLVRNQPQQHQLVRQRVKTLPGASKPQVVFETEEKRVKPKKASRMFQPVQIKFEEDQLRKEFFRDHPWELARPRVLVETSGKDYERYDWSRLQQPGKRLDGESVVQRQLWLLNNVPDMTKSAAYDIARREFYRLRLQEDIERRVAAEEAEATGATFGPTRLEIGMELENQEYERWKQWAKMEAQIQEQRAASFTGSALPSSEESAPVDEETEKVPQQV
What are the official names of this protein?
37S ribosomal protein S25, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS23 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y4171_XANC5
Sequence: MHAYVYKSQRKQDTFVYLATRDDFSGLPAAVQAQLAPLTFVLDVALTPERRLAQADAATVREALGKHGFYLQLPKTIVLAGECDHD
What are the official names of this protein?
YcgL domain-containing protein XCV4171.
Protein: MUTY_SALTY
Sequence: MQASQFSAQVLDWYDKYGRKTLPWQINKTPYKVWLSEVMLQQTQVTTVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGEFPQTFAEIAALPGVGRSTAGAILSLALGKHYPILDGNVKRVLARCYAVSGWPGKKEVENTLWTLSEQVTPARGVERFNQAMMDLGAMVCTRSKPKCTLCPLQNGCIAAAHESWSRYPGKKPKQTLPERTGYFLLLQHNQEIFLAQRPPSGLWGGLYCFPQFAREDELREWLAQRHVNADNLTQLNAFRHTFSHFHLDIVPMWLPVSSLDACMDEGSALWYNLAQPPSVGLAAPVERLLQQLRTGAPV
What is the function of this protein?
Adenine glycosylase active on G-A mispairs.  MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
What are the official names of this protein?
Adenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the Nth/MutY family.
Protein: PSBD_MAIZE
Sequence: MTIAVGRVTKEENDLFPLIDDWLRRDRFVFVGWSGLLLFPCAYFALGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWSQLGGLWTFLALHGAFALIGFMLRQFELARPVQLRPYNAISFSGPIAVFLSVFLIYPLGQSGWFFSPSFGVAAIFRFILFFQGFHNWTLKPFHMMGVAGVLGAVLLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSAIGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.