PharMolix/UniProtQA huggingface dataset:
Protein: RUVA_STAES
Sequence: MYAYIKGTLSQLFPTHVVVETCGIGYEIQTPNSYRFQKYLEKEVQIYTSLIVREDAQLLYGFINEEEKEMFLSLIKVTGIGPKSALAILASSTPHEVKLAIENENDAYLTQFPGIGKKTARQIVLDLKGKVTITEENSDDLLQTQVNGNEQNQIISEALLALQALGYSKRELTKVEKSLNKHNVNSVDEAVKIGLQTLVS
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: BBS4_CAEEL
Sequence: MEASNQDEIIGTDVIPNEQDNPEEVVPEPTSLDVPPPPPERAPSAPKRVEILDCNSLNGLMYHYFAQGDYIECKSIIGEIQSKYLERNEAAFHVRGLIARNEGELEEAMECFHKAYELSGKNKRYFYETGRCNFLLGRHQIAVEQLTKASEVMKDNPKVWYWLARAIYHFPAEKVQGKTFNPVESARTILMKPDIAKDATLICFLGRLCEELGDTSGAIAAYKSSLKLQPDNTEVMNLLGLIYLRTGQVQEGFVQLGNCLAYDPANSQAILTIGSIMQNHSDHDVALNKYRVAADVSDYNGCLWNNIGIGLLARNKPAASHSALKKAAFINPLNYKISYNLGVLHDIMNLHCSALHYIKLCTELYPQNAKAVGAMAVILSHMNDDKNARLAYKKSIELKKNPSTILNYAIFEYRMKDVTAASNALKLYKDLQASGVKCSANNKETANLLESVLKQPDQSAEQ
What is the function of this protein?
Component of the BBSome complex (By similarity).  The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia (By similarity).  The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function (By similarity).  Required for proper BBSome complex assembly and its ciliary localization (By similarity).  May be required for microtubule anchoring at the centrosome but not for microtubule nucleation (By similarity).  May be required for the dynein-mediated transport of pericentriolar proteins to the centrosome (By similarity).  Required, redundantly with bbs-5, for cilia biogenesis and both the assembly and movement of intraflagellar transport proteins along the ciliary axoneme (PubMed:22922713, PubMed:26150102).  Plays a role in the removal of degraded mechanosensory receptors within the cilia (PubMed:26150102).
What are the official names of this protein?
Bardet-Biedl syndrome 4 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the BBS4 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton. Cell projection, cilium membrane.
Protein: ZBT18_BOVIN
Sequence: MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEKATTEADSTKKEEDASSCSDKVESLSDGSSHMAGDLPSDEDEGEDEKLNILPSKRDLAAEPGNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDSADVDCVLDLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDYDMEHSTVKESVSTNNRVQYEPAHLAPLREDSVLRELEREDKASDDEMMTPESERVQVEGGMESSLLPYVSNILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGLRSKPAADVNVPTCSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIRKFHCELVNSLSVKSEALSLPAVRDWTLEDSSQELWK
What is the function of this protein?
Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development.  Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes.  Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis.  Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons.  May also play a role in the organization of chromosomes in the nucleus (By similarity).
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 18, Zinc finger protein 238.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family. ZBTB18 subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Associates with condensed chromatin.
Protein: RB6I2_HUMAN
Sequence: MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQSLNAAYATSGPMYLSDHENVGSETPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVASDTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQTNHKPSPDQIIQPLLELDQNRSKLKLYIGHLTTLCHDRDPLILRGLTPPASYNLDDDQAAWENELQKMTRGQLQDELEKGERDNAELQEFANAILQQIADHCPDILEQVVNALEESS
What is the function of this protein?
Regulatory subunit of the IKK complex.  Probably recruits IkappaBalpha/NFKBIA to the complex.  May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release.  May be involved in vesicle trafficking at the CAZ.  May be involved in Rab-6 regulated endosomes to Golgi transport.
What are the official names of this protein?
ELKS/Rab6-interacting/CAST family member 1, ERC-1, Rab6-interacting protein 2.
Protein: ATPB_AGRFC
Sequence: MAKAATPKKTAAVNGAGKVTQVIGAVVDVAFEGELPPILNALETQNNGNRLVLEVAQHLGENVVRTIAMDSTEGLVRGQSVADTGAPIEVPVGLETLGRIMNVIGEPVDEAGPIVTAKKRAIHQDAPSYVEQSTEGQILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESNVNKLGGGEGSKAALVYGQMNEPPGARARVALTGLTIAENFRDEGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGQMQERITTTNKGSITSVQAIYVPADDLTDPAPATSFAHLDATTVLSRSIAEKGIYPAVDPLDSTSRMLDPMIVGEEHYEVARKVQSTLQRYKSLQDIIAILGMDELSEEDKLTVARARKIERFLSQPFFVAEVFTGSPGKLVALEDTIKGFKGLVNGEYDSLPEAAFYMVGSMEEAIEKAKKLTAEAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS31_ARATH
Sequence: MATQISKKRKFVADGVFYAELNEVLTRELAEDGYSGVEVRVTPMRTEIIIRATRTQNVLGEKGRRIRELTSLVQKRFKFPVDSVELYAEKVNNRGLCAIAQAESLRYKLLGGLAVRRACYGVLRFVMESGAKGCEVIVSGKLRAARAKSMKFKDGYMVSSGQPTKEYIDAAVRHVLLRQGVLGIKVKIMLDWDPTGKSGPKTPLPDVVIIHAPKDDVVYSAPAQAAAPVTLVQEAPLTTVDYPEMIPPVA
What are the official names of this protein?
40S ribosomal protein S3-1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: HPRR_ECOLI
Sequence: MKILLIEDNQRTQEWVTQGLSEAGYVIDAVSDGRDGLYLALKDDYALIILDIMLPGMDGWQILQTLRTAKQTPVICLTARDSVDDRVRGLDSGANDYLVKPFSFSELLARVRAQLRQHHALNSTLEISGLRMDSVSHSVSRDNISITLTRKEFQLLWLLASRAGEIIPRTVIASEIWGINFDSDTNTVDVAIRRLRAKVDDPFPEKLIATIRGMGYSFVAVKK
What is the function of this protein?
Member of a two-component regulatory system HprR/HprS involved in response to hydrogen peroxide (PubMed:25568260, PubMed:27983483).  Regulates the expression of at least 5 operons, cyoABCDE, hprRS, hiuH, cusRS and cusCFBA.  Bifunctional regulator that acts as an activator and a repressor (PubMed:25568260).
What are the official names of this protein?
Transcriptional regulatory protein HprR, Hydrogen peroxide response regulator.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_CHLCH
Sequence: MAGKKYREAATKIERFRDYELAEAIEKVKEVTTTKFDATVDVAVKLGVDPRHADQVVRGTVMLPHGTGKTVSVLVICKETKAEEAKEAGADFVGFEEYITKIQEGWTGVDVIIATPDVMGQLGKVAKILGPRGLMPNPKSGTVTMDVAKAVKEVKAGKIEFRVDKAGNIHAPVGKVSFDSEHLNTNIVAFLKEVVRLKPSAAKGQYVQGIALSSTMSPSVKVKMDKFIS
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: Y1952_DICDI
Sequence: MTEINSGAPVSHMAHHIPKFAKYTKDIGLADPKKEIQYSIVLKIRNQEWIEKQVYVQNPTCENFGKLLGRGEINSLTKPSQAHFDKVSNFLQSKGIQSTRDGDNLKVLSSIEKTQDLFKTQIHKFTQPSGSQDDTIYKRVGGFQVPPEISDCVDLVVGF
What are the official names of this protein?
Uncharacterized protein DDB_G0291952.
Protein: CBP4_NEOFI
Sequence: MSRTGTWLKMLVAGTVICVGGPAFVQSIRPTDEELFKRYNPDLQKRSLEEGDRRAREFDEYVTRLKQWSKSDKSIWFAAQEQQEQKRAEIESQRSQAKEDARLQREEMRKELLGEK
What is the function of this protein?
Essential for the assembly of ubiquinol-cytochrome c reductase.  It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b (By similarity).
What are the official names of this protein?
Assembly factor cbp4, Cytochrome b mRNA-processing protein 4.
What is the protein family that this protein belongs to?
Belongs to the CBP4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: DLTB_BACSU
Sequence: MTPYSSFLFFILLGILLLPTIILGLNGKRFQAYNMFISIIILALIFSHDLHGVIALCLFTIWQVLLISGYLAYRQKANSGFVFCGAVIASILPLFLSKIWPFLSHPQPHHPPHNLISFLGISYLTFKGVQLIMEARDGLLKEQLPLHRLLYFILFFPTISSGPIDRYRRFVKDEQKAWTKEEYADLLYTGIHKIFIGFLYKFIIGYAINTYFIMNLPAITHNKILGNLLYMYGYSMYLFFDFAGYTMFAVGVSYIMGIKSPENFNKPFISKNIKDFWNRWHMSLSFWFRDYVFMRFVFWMTKKKWIKNRMAVSNIGYFLLFMLMGVWHGLAPQYIIYGLYHAVLMTCYNFFEKWNKKYKWLPSNRWTTILAIVITFHFVCFGFYIFSGKPFHHHH
What is the function of this protein?
O-acyltransferase that catalyzes D-alanylation of both teichoic acid and lipoteichoic acid (LTA) (PubMed:30283133).  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall (PubMed:7797557).  Catalyzes D-alanylation from DltC carrier protein (PubMed:30283133).
What are the official names of this protein?
Teichoic acid D-alanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound acyltransferase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PLCL1_RAT
Sequence: MAEGAASREAPAPLDVAGGEDDPRAGADAASGDAAPEASGGRMRDRRSGVALPGNAGVPADSEAGLLEAARATPRRTSIIKDPSNQKCGGRKKTVSFSSMPSEKKISSAHDCISFMQAGCELKKVRPNSRIYNRFFTLDTDLQALRWEPSKKDLEKAKLDISAIKEIRLGKNTETFRNNGLADQICEDCAFSILHGENYESLDLVANSADVANIWVSGLRYLVSRSKQPLDFMEGNQNTPRFMWLKTVFEAADVDGNGIMLEDTSVELIKQLNPTLKESKIRLKFKEIQKSKEKLTTRVTEEEFCEAFCELCTRPEVYFLLVQISKNKEYLDANDLMLFLEVEQGVTHVTEDMCLDIIRRYELSEDGRQKGFLAIDGFTQYLLSPECDIFDPEQKKVAQDMTQPLSHYYINASHNTYLIEDQFRGPADINGYVRALKMGCRSIELDVSDGPDNEPILCNRNNMAMLLSFRSVLEVINKFAFVASEYPLILCLGNHCSLPQQRVMVQQMKKVFGNKLYTEAPLSSESYLPSPEKLKHMIIVKGKKLPSESDLLEGEVTDEDEEAEMSRRVSGDYNGEQKHIWLCRELSDLVSICKSVQYRDFELSMKTQNYWEICSFSETLASRIANEYPEDFVNYNKKFLSRVYPSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPMMDLHTGWFLQNGGCGYVLRPSIMRDEVSYFSANTKGIVPGVSPLLLHIKIISGQNFPKPKGACAKGDVIDPYVCVEIHGIPADCSEQRTKTVQQNSDNPIFDETFEFQVNLPELTMVRFVILDDDYIGDEFIGQYTIPFECLQPGYRHVPLRSFVGDIMEHVTLFVHIAITNRSGGGKAQKRSLSVRMGKKVREYTMLRNIGLKTIDDIFKIAVHPLREAIDMRENMQNAIVSVKELCGLPPIASLKQCLLTLSSRLITSDSTPSVSLVMKDCFPYLEPLGTIPDVQKRMLAAYDLMIQESRVLIEMADTVQEKIVQCQKAGMEFHEELHNLGAKEGLKGRKLNKAIESFAWNITVLKGQGDLLKNAKNEAVENIKQIQLACLSCGLSKGPGSAAEAKGKRSLEAIEEKESSEENGKL
What is the function of this protein?
Involved in an inositol phospholipid-based intracellular signaling cascade.  Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol.  Component in the phospho-dependent endocytosis process of GABA A receptor.  Acts as an inhibitor of PPP1C.
What are the official names of this protein?
Inactive phospholipase C-like protein 1, PLC-L1, PRIP1, Phospholipase C-related but catalytically inactive protein, p130.
What is the protein family that this protein belongs to?
Belongs to the PRIP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 064L_IIV3
Sequence: MDAVKHPVSSLAPHRLGKGFYFMVNSKQIIKKFYNKSFLECSATQETSTTPHDRDNMDQAKLCSLVFEIFKKQTRLLAHLVLEEAIDLNNDLLFAVIYFNDEAILNSLVRHLYKYKPYYCDFTVRAQELDLVVHLDLGHCIDRLKSFIDPDTACFVLCSNLSQLTGLNCLKRVLKHKIIQKSYHLYLLLKTSHKVQQQWPDPVHVVEKYVTKRMVSYALTDNNPLLLAIVLDRLLVKLPTDDFAPLIVGIIESNRFKVECLPTLLQYHNRVKTTTKPIRI
What are the official names of this protein?
Uncharacterized protein 064L.
Protein: NUCS_CORJK
Sequence: MRLVIARCCVDYVGRLEAHLPPADRLILLKADGSVSIHADDRAYKPLNWMMPPCSLEAVEASSFDGDDAPTEYSELGNEGVEQLWIVTNPKGEQLRIQIFEIYSDTEHDLGEDPGLVKDGVEAHLQELLAEQIEILGEGYSLIRREYPTAIGPVDILSKDSTGATVAVEIKRRGGIDGVEQLTRYVELLNRDELLAPVTGVFAAQEIKPQARTLAEDRGFRCVTLDYEAMRGTDSSELRLF
What is the function of this protein?
Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
What are the official names of this protein?
Endonuclease NucS.
What is the protein family that this protein belongs to?
Belongs to the NucS endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF2_COLP3
Sequence: MFETNPILSKLKEIRERANLLRGYLDYDVKAERLVEVSRELELPDVWNEPERAQALGKERSSLEEVVNTIVELETGCEDIEGLVELAVEESDQETFDDAEVEADALDKVLEKLEFRRMFSGEQDANNSYLDIQSGSGGTEAQDWAEMLMRMYLRWGEAHGYKTEVIEVTDGDVAGIKGCTIKYTGEYAYGWLRTETGVHRLVRKSPFDSSGRRHTSFASAFIYPEIDDNIEIDINPADLRIDTFRASGAGGQHVNKTDSAIRITHEPTGAVVACQADRSQHKNRATAMKLLKAKLYEMEMQKQNSDKQVLEDGKSDIGWGSQIRSYVLDDSRIKDLRTGVENRNTQAVLDGDLDKFLEASLKSGL
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMA16_YEAST
Sequence: MPVTKSLSKLQKNLSKKGKNITVHPKGRKYEKLVRATMREDKIAAKKKLHQDKRVHELARVKFMQDVVNSDTFKGQPIFDHAHTREFIQSFIERDDTELDELKKKRRSNRPPSNRQVLLQQRRDQELKEFKAGFLCPDLSDAKNMEFLRNWNGTFGLLNTLRLIRINDKGEQVVGGNE
What are the official names of this protein?
Translation machinery-associated protein 16.
What is the protein family that this protein belongs to?
Belongs to the TMA16 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ADRC1_ARATH
Sequence: MASEKQKQHAQPGKEHVMESSPQFSSSDYQPSNKLRGKVALITGGDSGIGRAVGYCFASEGATVAFTYVKGQEEKDAQETLQMLKEVKTSDSKEPIAIPTDLGFDENCKRVVDEVVNAFGRIDVLINNAAEQYESSTIEEIDEPRLERVFRTNIFSYFFLTRHALKHMKEGSSIINTTSVNAYKGNASLLDYTATKGAIVAFTRGLALQLAEKGIRVNGVAPGPIWTPLIPASFNEEKIKNFGSEVPMKRAGQPIEVAPSYVFLACNHCSSYFTGQVLHPNGGAVVNA
What is the function of this protein?
Aldehyde reductase that catalyzes the reduction of the aldehyde carbonyl groups on saturated and alpha,beta-unsaturated aldehydes with more than 5 carbons (PubMed:21169366).  No activity on alpha,beta-unsaturated ketones (PubMed:21169366).  Can use propionaldehyde, butyraldehyde, methylglyoxal, (e)-2-pentenal, (E)-2-hexenal, (Z)-3-hexenal and (E)-2-nonenal as substrates, but not propenal (acrolein), crotonaldehyde, 2-butanone, 3-buten-2-one or 1-penten-3-one (PubMed:21169366).  May act as a short alcohol-polyol-sugar dehydrogenase possibly related to carbohydrate metabolism and the acquisition of desiccation tolerance (By similarity).  May also be involved in signal transduction (By similarity).
What are the official names of this protein?
NADPH-dependent aldehyde reductase 1, chloroplastic, AtChlADR1, Glucose and ribitol dehydrogenase homolog 1.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: COXX_BARHE
Sequence: MSIPRELSVASGSKSISPKPSVYDYITLLKPRVMLLVVFTALVGLIVSPVSINPLYGFLAILCIAVGGGGAGALNMWYDADIDAVMERTKSRPIPAGKISSRKAFIFGMVLSILSVLIMGSFVNWFAALFLAFTIFFYIVVYTIWLKRRTPQNIVIGGAAGAFPPMIGWAAATGTVNIESFLLFLIIFMWTPPHFWSLSLFSSLDYDAAGIPMMPNVRGEHSTKKQILFYTILMAICAAGPFIIGFAGVFYGIFSTVLSIIFIHFAYRLWKSNTYDATILMAKKTFFFSLFYLAAIFGILLIEFFVWCFIIL
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MSRA_LISMF
Sequence: MTKESLEKATFAGGCFWCMVKPFDTQPGIEKVISGYTGGHTVNPTYKEVCSGTTGHTEAIQITFDPAVFPYEKLVEVYWQQTDPTDAAGQFVDRGDSYRPVIFYHNEEQKEIAEKSKAALDASGRFKKPIVTEIAKAETFYPAEEYHQDFYKKEKAHYEGYQVASGRAAFIDANWKG
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: ATPG_STREM
Sequence: MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQIYASKIRQITTDLLKSDLTTGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSIMDMIQEYHAAGDYEIISIGSIGSDFFKARGMNVAFELRGLADQPSFDQVGRIISQSVDMFVNEIFDELYVCYNHHVNSLTSQVRVQRMLPISDLVAEEAAEEGVTGFELEPNRHVILEQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKHVINDLTIQYNRARQAAITQEITEIVAGANALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL4_DEIDV
Sequence: MAQINVIGKNGGRTIDLELPEVNAAILHDVVTWQLASRRRGTASTKTRAQVSKSGKKMYSQKGTGNARHGDRGVPTFVGGGVAFGPKPRSYGYTLPRKVRQLGLAMALADRQDGGKLIAVDGFDLDGKTKSFVSWAAQNGLDGSERVLIVTDDAQTRQSARNVAWATVLPVAGLNAYDILRHDRLVIDAVALEPAQEEVEQ
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: BIOF_GEOUR
Sequence: MQTFAEELAALRMEGLFRSMRLVEGNQSKRAVLDGREVLLLCSNNYLGLADHPLLKEAAIRAVERYGVGSGASRLVSGTMELHEALEARIAAFKGTNSALVFNSGYAANTGIISAIAGRGDVIFSDRLNHASIVDGALLSRARFVRYPHNNISVLRRLLEDTEVASGRRLIVTDGVFSMDGDLAKLSELVALKKEFDALLMVDDAHGTGVLGDGGRGSAEQCGVMAEVDIHMGTLGKALGSFGAYAAASREIIDYLVNRARSFIFSTSLPPAVLAASQAAFELVDSPSGAALRLALAANTIRFKAGLQAVGFDTMGSETQIVPVYVGGAQQTMEFSRLLLEEGVFVQGIRPPTVPAGSCRLRCTLMATHSENDLDQAITAITAIGEKLGVI
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: RS6_SHEON
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYTGAITEANGKIHRLEDWGRRQLAYPIQDLHKAHYVLMNVEAPAETIEELETAFRFNDAVLRNMVMRTKGAITEASPMAKAKDERDSRRGPAGDRSYDEANAEEIAE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: XYLG_ECOLI
Sequence: MPYLLEMKNITKTFGSVKAIDNVCLRLNAGEIVSLCGENGSGKSTLMKVLCGIYPHGSYEGEIIFAGEEIQASHIRDTERKGIAIIHQELALVKELTVLENIFLGNEITHNGIMDYDLMTLRCQKLLAQVSLSISPDTRVGDLGLGQQQLVEIAKALNKQVRLLILDEPTASLTEQETSILLDIIRDLQQHGIACIYISHKLNEVKAISDTICVIRDGQHIGTRDAAGMSEDDIITMMVGRELTALYPNEPHTTGDEILRIEHLTAWHPVNRHIKRVNDVSFSLKRGEILGIAGLVGAGRTETIQCLFGVWPGQWEGKIYIDGKQVDIRNCQQAIAQGIAMVPEDRKRDGIVPVMAVGKNITLAALNKFTGGISQLDDAAEQKCILESIQQLKVKTSSPDLAIGRLSGGNQQKAILARCLLLNPRILILDEPTRGIDIGAKYEIYKLINQLVQQGIAVIVISSELPEVLGLSDRVLVMHEGKLKANLINHNLTQEQVMEAALRSEHHVEKQSV
What is the function of this protein?
Part of the ABC transporter complex XylFGH involved in xylose import.  Responsible for energy coupling to the transport system (Probable).  The XylFGH system can also transport ribose in absence of xylose.
What are the official names of this protein?
Xylose import ATP-binding protein XylG.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYM_LEGPA
Sequence: MTSERKMLVTSALPYANGHLHLGHLVEHIQTDIWVRTHKMLGIQCISVCGDDAHGTPIMLKAEQLGITPEALTAEIKLSHEKDFKAFAIDYDYYHTTHSPENQVLATTIFERLQAGGDIVKKTIRQFYDPVKQMFLPDRYVKGTCPKCAAVDQYGDNCEVCGATYSPTDLINPVSVISGASPVEKESEHYFFDLPLYEELLKDWTRKGHLQAEVTNKLSEWFEAGLKQWDISRDAPYFGFPIPGVPDKYFYVWLDAPIGYMASFKKYCDERGVSFDEFWDKASKTELYHFVGKDIVYFHALFWPAMLAASGFRTPTAVYTHGFLTVEGQKMSKSRGTFIEARAYLAHLHPEYLRYYFAAKLNGRVDDLDLNFDDFVNRVNADLVGKVVNIASRCAGFINKRFDNRLSSELNDPKLHNDLLSARESVIDAFVSRDYARAIRQIMDCADKVNQYIDANKPWVLAKDESKLNEVHAICTMGINLFRILITYLKPVLPMMAKASEEFLNSEPLHWGSIDKPLLNHRINTFKPLMVRVEKEKIEAMLVQSKESLMTTPVKENTPVEDANLISIEDFAKVDLRIAKIVNAEPVEGADKLMRLILDLGDAQKQVFAGIKKAYDAEELIGRLTVMVANLEPRTMRFGVSEGMVLAAGDGQGIYLLQPDAGALPGMKVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.