PharMolix/UniProtQA huggingface dataset:
Protein: KDGD_ACIBS
Sequence: MDALELKNIISDGLLSFPVTDFDQNGDFNKSSYAKRLEWLAPYGASALFAAGGTGEFFSLTGNEYSEVIKTAVDICKGSVPIIAGAGGPTRQAIEQAKEAERLGAHGILLMPHYLTEASQEGLIEHVKQVCNSVDFGVIFYNRSVSRLNLDSIQKLTEMCPNLIGFKDSSGQIDMMTAVTQTIGDRLSYLGGLPTAEVFAAPYKALGCPVYSSAVFNFIPKTAMEFYNALRSDDFETTNRLIKDFFLPLIKIRDRKSGYAVSMIKAGAKIVGHDAGPVRPPLSDLTQADYEDLAALIATLGPQ
What are the official names of this protein?
Probable 5-dehydro-4-deoxyglucarate dehydratase, 5-keto-4-deoxy-glucarate dehydratase, KDGDH.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
Protein: RSMG_LACP7
Sequence: MRDNSTFIQGLRSLGMDLNKHQLEQFEIYYDLLIEWNSFMNLTAITEYEEVIQKHFLDSLSLIKSYQIKTGDTLLDMGTGAGFPGIPLKIAYPDLNVLLMDSLNKRINFLNEVINRLELKNISAMHGRAEEQARKLDFREKFDIVVSRAVARTASLAELCLPYVKKGGYFIPYKSGKVTEELEEAEYALECLGGKLEEKVTFSLPDTDMERTLICIKKVKETPKSYPRAGGKPLKMPLIRKK
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_PSYA2
Sequence: MVVIRLARGGAKKRPFYQVVVADQRRARDGRYIENIGFFNPLAKDSEEAVRLNMEAYNAWVAKGAQPSDRVASLAKAYNKSAAQTEATA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: O4C45_HUMAN
Sequence: MNNVTEFILLGLTHNPELQKFLFVMFLITYLITLAGNLLISVIIFISPALGSPMYLFLSYLSIIDIFYSSSIAPKMIFDLISENNTISFNGCMTQLFTEHFFAAAETILLSVMAYDCYVAICKPLHYATIMTQSMCGFLMVVAGILGFVHGGIQTLFIAQLPFCGPNVIDHFMCDLVPLLELACTDTHTLGPLIAANSGSLCFLIFSILDASYVIILCSLRSHSSEGHLKALSSCASHIFTVILFFVPCSYLYLRPLTSFPTDKAVTVFCTLFTPMLNPLIYTVKNKAVKNVIKKLWKQIMTTDDK
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 4C45.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SPT4_CANAL
Sequence: MSSRSERACMLCGIIQPMKSFIDYGCPNCESLLHYQYNDNKQVQDCTSPSFEGLVALGEDNKGSWVARWLRIDSFTAGLYAVKVNGKLPPSIIAELEEQNVIYRPRDGSAED
What is the function of this protein?
The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing.  This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity).
What are the official names of this protein?
Transcription elongation factor SPT4, Chromatin elongation factor SPT4.
What is the protein family that this protein belongs to?
Belongs to the SPT4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Centromere and heterochromatin.
Protein: RL18_BOVIN
Sequence: MGVDIRHNKDRKVRRKEPKSQDIYLRLLVKLYRFLARRTNSTFNQVVLKRLFMSRTNRPPLSLSRMIRKMKLPGREGKTAVVVGTITDDVRVQEVPKLKVCALRVSSRARSRILKAGGKILTFDQLALDSPKGCGTVLLSGPRKGREVYRHFGKAPGTPHSHTKPYVRSKGRKFERARGRRASRGYKN
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL18 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: RL25_ACTPJ
Sequence: MSFKFEAEVRSAQGKGASRRLRHNGQVPAIIYGGNAEPVSIILDHDKVNNAQAHDAFYNEVLTIVVAGKEEQVKVQAIQRHPTKPKLVHLDFKRA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: RIR1_VARV
Sequence: MFVIKRNGYKENVMFDKITSRIRKLCYGLNTDHIDPIKIAMKVIQGIYNGVTTVELDTLTAEIAATCTTQHPDYAILAARIAVSNLHKETKKLFSEVMKDLFNYVNPKNGKHSPIISSITMDVVNKYKDKLNSVIIYERDFSYNYFGFKTLEKSYLLKINNKIVERPQHMLMRVAVGIHQWDIDSAIETYNLLSEKWFTHASPTLFNAGTSRHQMSSCFLLNMMDDSIEGIYDTLKRCALISKMAGGIGLSISNIRASGSYISGTNGASNGIIPMLRVYNNTARYIDQGGNKRPGVMTIYLEPWHSDIMAFLDLKKNTGNEEHRTRDLFIALWIPDLFMKRVKDDGEWSLMCPDECPGLDNVWGDEFERLYTLYEREKRYKSIIKARVVWKAIIESQIETGTPFILYKDACNKKSNQQNLGTIKCSNLCTEIIQYADANEVAVCNLASIALNMFVIDGQFDFLKLKDVVKVIVRNLNKIIDINYYPIPEAEISNKRHRPIGIGVQGLADAFILLNYPFDSLEAQDLNKKIFETIYYGALEASCELAEKEGPYDTYVGSYASNGILQYDLWNVVPSDLWNWEPLKDKIRTYGLRNSLLVAPMPTASTAQILGNNESVEPYTSNIYTRRVLSGEFQVVNPHLLRVLTERKLWNDEIKNRIMVDGGSIQNTNLPEDIKRVYKTIWEIPQKTIIKMAADRGAFIDQSQSMNIHIADPSYSKLTSMHFYGWSLGLKTGMYYLRTKPASAPIQFTLDKDKIKPLVVCDSEICTSCSG
What is the function of this protein?
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis.  Allows virus growth in non-dividing cells.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase large subunit, Ribonucleotide reductase large subunit, Ribonucleotide reductase subunit 1, RNR1.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase large chain family.
Protein: ACPS_SOLUE
Sequence: MIVGTGVDLAEVDRIQRSIERYGDKFIKRIYTPGEIAYVERKANKFERYAARFAAKEAGMKAIGTGWRHGVRWQDFEVANLRTGKPTLLLHGVAARYAEKLGVKNIALSITHTAALGMAHVILEN
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_RICM5
Sequence: MAVKIRLARGGAKKRPFYRVVVANATAPRDGDFLEKVGTYDPMLALDNSERVVLKKDRIEYWLGTGAKPTERVAKFIEQAGVTLPEKVKKEMEVKAKNRKARPSKKEDKEA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: THIE_CHLL2
Sequence: MIPSSPFLCFITDESRSPIILARKALEGGASMIQLRHKSADGDQLYHWSVAIQALCRKHKAIFIVNDRVDIALAAGADGVHLGQQDLPADAARKLLGKDRIMGISVSSPLEALAAEKNGADYVGFGHIFPTSSKDKKNTPVGPESIADIKAIITIPIIAIGGITGCNAQLPIRAGAAGIAVIAAVSRAADPEIAARELVGILQKNIEHNR
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: CYAA_LEIDO
Sequence: MAMQIRPSLGGCLRHGGAGDHAARRLSRLRAAKVFVPTAVVCVLLCCAPWVMAEITNDAEREPVYILNAMYSTEAYTNEDAKALWTGMDMAFYNSHYKAAGGRPIKILHPDPDQDNLYDIAEVILHSLARQEKLLAVLGPYLDGRLTAALSNADVVQSGLMLIAPFTGSSGVRTWSDSVYFTRAEPMVELKVVLMHIVNRLRARRVAFMRLTGMHFGGEELTYVQDTLTSLLRDPAVLYTVPYSESSVEVDEEAFDAMADTNPQVIIVWAAPVQQVIYFLEKVLTDPRTSSAYVISCSMIQRVVFDVYKRLLSAGSIKPQDGRILASATTSPVSGEGLKYMEVLKAQMSNYIENSGSFDYYPDDDSTETLGRKARSEAPLSRKYTVDEFFQAHPSIAKLMALGWLSGTLVQQTLEQTDWIVNRSTYKAGLFNQNRFVIGGDYVLGDYGGPCEPLAQFLGASCYCNQGGHSSILTVLQNASWDIVPDSSFKYPQSECNSSKSQIVKAVSVLALLNQGYPKLIDAGMQLNEVLPHAFDDNLCKGYKVSSIFLRVETAKAQQLFDAEVSNYSVDIIAGPIFQALDVGEIFVLNPLYNHPQLRTEKRNYVYLMPTLEQQIYVMYSKIDALRTRTDVFEDTAVVLRGYSAQEVVEISEILFKTAGTFNLPDPSVATISFTDSLRGLLSPRAINVVIGMKDGDSAHFANFLAKYTDVMVVVCFDELTMYYEELRATFSVQPTSVQARLMSFSSLPLWTDASAEAKARWPILGHFHKIFPDPINHTPSLLRDVIIAGFIQELVSTTTVAETKLLTNAVYINGGVTTYGFTLGNFEWGCTATTSGDSCVYKNYGASNIEILSIQRMLDPTVPQLSSPSTPTMEYRPRQRSHALTPAQRNGLIAGCVVGAVVLIATCTLLLYCCMDNRNNDAAPKDGDEPVTLLFTDIESSTALWAALPQLMSDAIAAHHRVIRQLVKKYGCYEVKTIGDSFMIACRSAHSAVSLACEIQTKLLKHDWGTEALDRAYREFELARVDTLDDYEPPTARLSEEEYAALWCGLRVRVGIHTGLTDIRYDEVTKGYDYYGDTSNMAARTEAVANGGQVVATEAAWWALSNDERAGIAHTAMGPQGLRGVPFAVEMFQLNAVPGRRHAALRTEIEAILPDDTATDTASSAAGALLSSVETMSDPAAGIAFVLASCFAPYPVAQRVRELQPLLSKWGVGAPPRSRLVSEEDYCQGLMNRLAIRIATVSQARLRLTREDAADGKFKLASSEALNPLAREGDSAAGGVRPRLPGSPVTSLPAGGSSSMREWRVFTRLMNDTQHPSVTHLSQQRPSNLTSFTEAQDAAFPLNAHCGPESRVENSGADDEEIVIVRVSRNPHYARHAFE
What is the function of this protein?
Could act as a receptor for an unknown ligand.
What are the official names of this protein?
Receptor-type adenylate cyclase A, ATP pyrophosphate-lyase, Adenylyl cyclase.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-3 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RNZ_LEVBA
Sequence: MEIEFLGTGAGSPGKFRNVTSTALRLLDERNSVWLFDVGEATQHQILRTTLKPRKIDKIFITHLHGDHIFGLPGLLSSRSFQGGDAPLTIYGPKGIRNFVEVSLRVSETKLSYKIRYQELTTDGLVFEDGKFRVYAQHLDHRIECFGYRIEEKDHPGELQVEQLQAAKIPSGPVYGQLKAGKTVTLPDGRVINGADFLGPAQPGRIVAILGDTRQTPNAEKLAINADVLVHESTFAKGESKLARSYYHSTNIQAAELAKRMHVKQLLLNHISARYTGKMAAELQHQAREVFKQTRVVKDFDEIEVPFEKLTKEGTPS
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: NCOR1_RAT
Sequence: KDKGPPPKSRYEEELRTRGKTTITAANFIDVIITRQIASDKDARERGSQSSDSSSSLSSHRYEAPSDAIEVISPASSPAPPQEKPQTYQPEMVKANQAENESPQQYEGPLTHYRSQQGSPSPQQQPPLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVPSQPSTSTFQTSPSALSSTPVRTKPSSRYSPESQSQTVLHPRPGPRVSPENLVDKSRGSRPGKSPERSHIPSEPYEPISPPQGPAVHEKQDSMLLLSQRGMDPAEQRSDSRSPGSISYLPYFFTKLESTSPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGAVSSRSHSFADPASNLGLEDIIRKALMGSFDDKVEDHGVVMPHPVGVVPGSASTSVVTSSETRRDEGDPSPHSGVCKPKLINKSNSRKSKSPIPGQNYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQFPYNPLTIRMLSSTPPTPIACAPSAITQAAPHQQSRIWEREPAPLLSAQYETLSDSDD
What is the function of this protein?
Mediates transcriptional repression by certain nuclear receptors.  Part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors.  Participates in the transcriptional repressor activity produced by BCL6.  Recruited by ZBTB7A to the androgen response elements/ARE on target genes, negatively regulates androgen receptor signaling and androgen-induced cell proliferation (By similarity).  Mediates the NR1D1-dependent repression and circadian regulation of TSHB expression (By similarity).  The NCOR1-HDAC3 complex regulates the circadian expression of the core clock gene ARTNL/BMAL1 and the genes involved in lipid metabolism in the liver (By similarity).
What are the official names of this protein?
Nuclear receptor corepressor 1, N-CoR, N-CoR1.
What is the protein family that this protein belongs to?
Belongs to the N-CoR nuclear receptor corepressors family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CLPP3_ARATH
Sequence: MEMSLRLASSSTSNPICLLNPGKNLNFPIRNHRIPKTSKPFCVRSSMSLSKPPRQTLSSNWDVSSFSIDSVAQSPSRLPSFEELDTTNMLLRQRIVFLGSQVDDMTADLVISQLLLLDAEDSERDITLFINSPGGSITAGMGIYDAMKQCKADVSTVCLGLAASMGAFLLASGSKGKRYCMPNSKVMIHQPLGTAGGKATEMSIRIREMMYHKIKLNKIFSRITGKPESEIESDTDRDNFLNPWEAKEYGLIDAVIDDGKPGLIAPIGDGTPPPKTKVWDLWKVEGTKKDNTNLPSERSMTQNGYAAIE
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins (By similarity).  In the absence of CLPP3, modified ClpPR core(s) could be formed, albeit at strongly reduced levels (PubMed:23548781).
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 3, chloroplastic, Endopeptidase ClpP3, nClpP3, nClpP4.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
Protein: PSBA1_SYNJA
Sequence: MTTVIQRRSTSNVWEQFCEWVTSTDNRLYIGWFGVLMIPTLLTATTCFIIAFIGAPPVDIDGIREPVSGSLLYGNNIITGAVVPSSAAIGLHFYPIWEAASLDEWLYNGGPYQLIVLHFLIGVFCYMGREWELSYRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMLVFQAEHNILMHPFHQLGVAGVFGGALFSAMHGSLVTSSLIRETSEEESQNLGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVIGIWFTALGISIMAFNLNGFNFNQSIVDSNGRVVGTWADVLNRANLGMEVMHERNAHNFPLDLAAVEVAPAIRG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1 1, PSII D1 protein 1, Photosystem II Q(B) protein 1.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: Y425_METJA
Sequence: MVQVVYPNMADLEIGNVKEVYNKILASLNEYYGKMFENLVFEMLKLKIIDFGQKSVAKWWHKGEEIDVLAYNNNKMIAFEVKWKDLSFKEAKGILRDLERKLDKVDFDGEKECYIIAKSIEGKEKLKALDLMDLEKLIIF
What are the official names of this protein?
Uncharacterized protein MJ0425.
Protein: WDR4_HUMAN
Sequence: MAGSVGLALCGQTLVVRGGSRFLATSIASSDDDSLFIYDCSAAEKKSQENKGEDAPLDQGSGAILASTFSKSGSYFALTDDSKRLILFRTKPWQCLSVRTVARRCTALTFIASEEKVLVADKSGDVYSFSVLEPHGCGRLELGHLSMLLDVAVSPDDRFILTADRDEKIRVSWAAAPHSIESFCLGHTEFVSRISVVPTQPGLLLSSSGDGTLRLWEYRSGRQLHCCHLASLQELVDPQAPQKFAASRIAFWCQENCVALLCDGTPVVYIFQLDARRQQLVYRQQLAFQHQVWDVAFEETQGLWVLQDCQEAPLVLYRPVGDQWQSVPESTVLKKVSGVLRGNWAMLEGSAGADASFSSLYKATFDNVTSYLKKKEERLQQQLEKKQRRRSPPPGPDGHAKKMRPGEATLSC
What is the function of this protein?
Non-catalytic component of the METTL1-WDR4 methyltransferase complex required for the formation of N(7)-methylguanine in a subset of RNA species, such as tRNAs, mRNAs and microRNAs (miRNAs) (PubMed:12403464, PubMed:31031084, PubMed:31031083, PubMed:36599982, PubMed:36599985).  In the METTL1-WDR4 methyltransferase complex, WDR4 acts as a scaffold for tRNA-binding (PubMed:36599982, PubMed:36599985).  Required for the formation of N(7)-methylguanine at position 46 (m7G46) in a large subset of tRNAs that contain the 5'-RAGGU-3' motif within the variable loop (PubMed:12403464, PubMed:34352207, PubMed:34352206, PubMed:36599982, PubMed:36599985).  M7G46 interacts with C13-G22 in the D-loop to stabilize tRNA tertiary structure and protect tRNAs from decay (PubMed:36599982, PubMed:36599985).  Also required for the formation of N(7)-methylguanine at internal sites in a subset of mRNAs (PubMed:31031084).  Also required for methylation of a specific subset of miRNAs, such as let-7 (PubMed:31031083).  Independently of METTL1, also plays a role in genome stability: localizes at the DNA replication site and regulates endonucleolytic activities of FEN1 (PubMed:26751069).
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4, Protein Wuho homolog, hWH, WD repeat-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the WD repeat TRM82 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes at the site of nascent DNA synthesis.
Protein: MIAB_BURP1
Sequence: MTKKVYVKTFGCQMNEYDSDKMVDVLNAAEGLEKTDTPEDADIILFNTCSVREKAQEKVFSDLGRVRELKEAKPDLLIGVGGCVASQEGASIVARAPYVDLVFGPQTLHRLPQMIDARRESGRAQVDITFPEIEKFDHLPPARVEGPSAFVSIMEGCSKYCSYCVVPYTRGDEVSRPLDDVLTEVAGLADQGVREVTLLGQNVNAYRGAIAAGSAEIADFATLIEYVADIPGIERIRYTTSHPKEFTQRLLDVYAKVPKLVDHLHLPVQHGSDRILMAMKRGYTVLEYKSVIRKLRAIRPNLSLSTNIIVGFPGETDADFDKTMALVHEMSYDTSFSFIYSPRPGTPAANLADDTPRELKLKRLQHLQATIEENVARISQSMLGKVERILVEGPSRKDPNELAGRTENNRVVNFPAPSAAHPRLIGQMIDVKINHAYPHSLRGELVLAHGDASAATH
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSHD_NOCFA
Sequence: MGDITVRWTQRLDGETADAVRELLAAASAADGVAPVSEQAVLSLGEPGAARHLLAEHDGELAGYANLVPAHGDHPAMAEAAVAPARRGRGIGTALVREALAAGGADARVWAHGDRPAAKAVAARLGLRTARELWQMRRSLATPQLPELVVPDGIVLRTYAGPADDAELLRVNNAAFDWHPEQGGWTQRDIAVRRAESWFDPAGLFLATDTAAPDRVLGFHWTKVHADEQPPVGEVYVVGIDPAAQGRGLGRLLTLAGLHHLRERGLGGVLLYTEADNTAAVNTYTKLGFAPAHVDVAYAANGA
What is the function of this protein?
Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
What are the official names of this protein?
Mycothiol acetyltransferase, MSH acetyltransferase, Mycothiol synthase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. MshD subfamily.
Protein: UBE2N_BOVIN
Sequence: MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
What is the function of this protein?
The UBE2V1-UBE2N and UBE2V2-UBE2N heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains.  This type of polyubiquitination does not lead to protein degradation by the proteasome.  Mediates transcriptional activation of target genes.  Plays a role in the control of progress through the cell cycle and differentiation.  Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.  Acts together with the E3 ligases, HLTF and SHPRH, in the 'Lys-63'-linked poly-ubiquitination of PCNA upon genotoxic stress, which is required for DNA repair.  Appears to act together with E3 ligase RNF5 in the 'Lys-63'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD.  Promotes TRIM5 capsid-specific restriction activity and the UBE2V1-UBE2N heterodimer acts in concert with TRIM5 to generate 'Lys-63'-linked polyubiquitin chains which activate the MAP3K7/TAK1 complex which in turn results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genes.  Together with RNF135 and UB2V1, catalyzes the viral RNA-dependent 'Lys-63'-linked polyubiquitination of RIGI to activate the downstream signaling pathway that leads to interferon beta production (By similarity).  UBE2V1-UBE2N together with TRAF3IP2 E3 ubiquitin ligase mediate 'Lys-63'-linked polyubiquitination of TRAF6, a component of IL17A-mediated signaling pathway.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 N, E2 ubiquitin-conjugating enzyme N, Ubiquitin carrier protein N, Ubiquitin-protein ligase N.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: RKD2_ARATH
Sequence: MADHTTKEQKSFSFLAHSPSFDHSSLSYPLFDWEEDLLALQENSGSQAFPFTTTSLPLPDLEPLSEDVLNSYSSASWNETEQNRGDGASSEKKRENGTVKETTKKRKINERHREHSVRIISDITTYTTSSAPTTLSKETVSRYFYMPITQAAIALNVGLTLLKRRCRELGIRRWPHRKLMSLNTLISNVKELQKMEGEENAEKLQDALEMLEKEKRTIEDLPDLEFKDKTKRLRQACFKANHKRKKKRSLKSDQSQVPSCSSSGSVPSDESVDEAGMESDEEMKYLLCGFSSEFTSGL
What is the function of this protein?
Putative transcription factor.
What are the official names of this protein?
Protein RKD2, AtRKD2, RWP-RK domain-containing protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: PGA58_CANAL
Sequence: MQFSTLVSLAAVIVSTNAAALLTQTVESSTVVTITSCGPEHTNCPASSPATPAPAPSASAPAPPAPEQPEPSAPAPAPSAPAPEQPEQPATPATPAAPATPATPAAPEPSAPAPEQPASPAAPAPAPSAPAPAPEQPEQPAAPTTKEAESTPAPAPSAPAPPAPEQPESAPAPAPSAPAPEQPESSPAPAPSAPASVPEQPASSVSNSTGPSSVPTFEGAAAKQYITGSVAVIAAALLAL
What are the official names of this protein?
Predicted GPI-anchored protein 58.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: HFQ_PSEPG
Sequence: MSKGHSLQDPYLNTLRKEKVPVSIYLVNGIKLQGSIESFDQFVVLLKNTVSQMVYKHAISTVVPARPVRLPSPTDGEHGDSEPGNA
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: SCGR1_HUMAN
Sequence: MGCCGCGGCGGCGGCGGGCGGGCGRCTTCRCYRVGCCSSCCPCCRGCCGGCCSTPVICCCRRTCSSCGYSCGKGCCQQKCCCQKQCCC
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Small cysteine and glycine repeat-containing protein 1, Keratin-associated protein 28-1.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 28 family.
Protein: Y661_YERPE
Sequence: MKRTKNINQETFRKSWRSYRLAPVALAVSAVFMLAGCEKTDETVSLYQNADDCSQANPSQSAECTTAYNTALQEAVKTAPKYATREDCVAEFGESQCTQAPAQAGMVPTSSSETTAAAPQQSGSMWMPLMAGYMMGRMMGGGASQPLFTSKAPNSPANGKFVDASGKNFGAATTGRTMTVPKTALAPKPAVTKTITRGGFGESVAKQSSMQRSAATSSKTTTRSMGG
What are the official names of this protein?
UPF0441 protein YPO0661/y3517/YP_2976.
What is the protein family that this protein belongs to?
Belongs to the UPF0441 family.
Protein: DXR_HERAR
Sequence: MQHITILGSTGSIGVSTLDVVARHPDRYRVHALTAQNKVEELAAQCAQFHPDVAVVGSAEAAQKLQVLLNGMGLQTQVEYGAAALCTVASAPECDCVMAAIVGGAGLAPTLAAARAGKKILLANKEALVMSGPLLMEAVAASGAILMPIDSEHNAIFQCMPATYHQQQLTPAQHGIEKILLTASGGPFLNRALDTLDQVTCAEAIAHPKWVMGRKISVDSATMMNKGLEVIEAHWLFGVPADRIEVVIHPQSVVHSMVSYIDGSVLAQLGNPDMRTPIAHAMAYPERIDSGVAPIDLIKIAQLTFEHPDLLRFPCLKLAYDALQAGGSAPAIMNAANEIAVQAFLDGRIGFRAIDQLIARVMAALPSSPVTDIDTVFEQDRRARDTAASFI
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: MDH_EHRRW
Sequence: MIQSKKIALIGSGNIGGMIAYLIRLKNLGDVVLLDINDGMAKGKALDIAESSPIGKYNGEIFGTNNYADIENADAIIVTAGITRKPGMSRDDLISTNVNIIKEIATNIAKYAPNAFVIVVTNPLDVMVLAMYRYSHLPSNMIVGMAGVLDSARFSYFIAKELNVSVESVDSLVLGGHGDIMLPLIRYSSVSGVSIADLIKLGMITHDKVTEIVERTRKGGEEIVSLLKTGSAYYAPAESAVLMLDSYLNDKKLMLPCSAYLKGEYGVHDLFVGVPIIIGKNGVEKIVELQLTEEENSIFNNSVALIQNLVANI
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.