PharMolix/UniProtQA huggingface dataset:
Protein: VTC4_SCHPO
Sequence: MKFGQLLKETLMYEYKYSYVNYDKLKKEIKRRNDQGGWSEEDESDFVELLEKELDKVYSFQKNKSAEVMERIRFCEEQTDEVVRRLDSDNPPNENDFAILETELTDIMATVHDLAKFSELNYTAFYKIIKKHDKHTGWILKPVFAARLNAKPFFKEQYDLLVVKLSKLYDFVRTRGSPIKGDSAAGGTQQNFVRQTTKYWVHPNNVTELKIYILKHLPVLVFNPNKEFAREDAAITSIYYDNDDLDFYLGRLEKREGAEAIRLRWYGNMDNNNIFVERKTHREDWTGEKSVKARFPLKEKYVNAFLRGDYTVEEAFAKMRKDGKKSLKEIESLERLAKEVQYTVLSRGMKPYVRSFYERTAFQLPGDARVRISLDTNLSLIREDGPSRAGNNWRRMDIGIDYPFDQLPDEDIVRFPYAILEVKLQTQFGQDPPEWVNNLVNSHLVEAVPKFSKFIHGVSTLFYDRVTLLPYWFPQMDIDIRKPATHTFIQGRSQSGTHSSSVSANVLTDSENTPIHADGDNYVDEESRIGSSSTRNDNSTFQTSDSFQELDERTNLLDISKRKGRDSFVAALNSRLKDIKDSFFLETVPKFEEPTEPTVIYEQKYVSPPGKRIYVPVRVEPKTYFALERTYLDYLRYSILMGSIGITLFSFAKTRSGILGAASFTLVALFAIFYSTFLYLWRAVNIAKHNAVRYDDRFGPTAICVITFAAISANVILNFNA
What is the function of this protein?
Catalytic subunit of the vacuolar transporter chaperone (VTC) complex.  The VTC complex acts as vacuolar polyphosphate polymerase that catalyzes the synthesis of inorganic polyphosphate (polyP) via transfer of phosphate from ATP to a growing polyP chain, releasing ADP.  VTC exposes its catalytic domain vtc4 to the cytosol, where the growing polyP chain winds through a tunnel-shaped pocket, integrating cytoplasmic polymer synthesis with polyP membrane translocation.  The VTC complex carries 9 vacuolar transmembrane domains, which are likely to constitute the translocation channel into the organelle lumen.  PolyP synthesis is tightly coupled to its transport into the vacuole lumen, in order to avoid otherwise toxic intermediates in the cytosol, and it depends on the proton gradient across the membrane, formed by V-ATPase.  The VTC complex also plays a role in vacuolar membrane fusion.
What are the official names of this protein?
Vacuolar transporter chaperone complex subunit 4, Polyphosphate kinase, SPX-dependent polyphosphate polymerase VTC subunit 4, Vacuolar membrane polyphosphate polymerase catalytic subunit, PolyP polymerase.
What is the protein family that this protein belongs to?
Belongs to the VTC4 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: ACYP_CORGB
Sequence: MEKVRLTAFVHGHVQGVGFRWWTTSQAQELKLAGSASNLSDGRVCVVAEGPQTQCEELLRRLKENPSSYRRPGHVDTVIEQWGEPRDVEGFVER
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: MIAB_XANC5
Sequence: MPGTPVSDLSAAAAVDAPALLPLPVARPSAPAVVRGKLYIKTHGCQMNEYDSAKMADVLAASEGLELTDNPEEADVVLVNTCSIREKAQEKVFSQLGRWKALKAGGKPVIIGVGGCVASQEGEAIVKRAPYVDLVFGPQTLHRLPELIRARRESGKSQVDISFPEIEKFDRLPEPRAEGPSAFVSIMEGCSKYCSFCVVPYTRGEEVSRPFEDVLVEVAQLAAQGVREINLLGQNVNAYRGAYGADAGDAAQYADLGLLIRTIAQIEGIGRIRFTTSHPLEFSDSLVDAYRDVPQLANYLHLPVQAGSDRILSAMKRGYTALEFKSKIRKLRAVRPDISISSDFIVGFPGETEADFEKTMKLIEDVGFDQSFSFVYSRRPGTPASDLQDDTPEAVKQARLARLQAHINAHAASISQSMVGSVQRVLVEGPSRRDPNELTGKSENMRPVNFPGNPRLIGQFVDVLITEAMSNSLRGRIQLDDSAQ
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR4_NEIG1
Sequence: MPLRGVTALSDFRVEKLLQKAAALGLPEVKLSSEFWYFAGSEKALDAATVEKLQALLAAQSVEQTPEAREGLHLFLVTPRLGTISPWASKATNIAENCGLAGIERIERGMAVWLEGALTDEQKQQWAALLHDRMTESVLPDFQTASKLFHHLKSETFSTVDVLGGGKEALVKANTETGLALSADEIDYLVENYQALQRNPSDVELMMFAQANSEHCRHKIFNADFILNGEKQPKSLFGMIRDTHNAHPEGTVVAYKDNSSVIKGAKIERFYPNAAENQGYRFHEEDTHIIMKVETHNHPTAIAPFAGAATGAGGEIRDEGATGKGSRPKAGLTGFTVSNLNIPDLKQPWEQDYGKPEHISSPLDIMIEGPIGGAAFNNEFGRPNLLGYFRTFEEKFDGQVRGYHKPIMIAGGLGSIQAQQTHKDEIPEGALLIQLGGPGMLIGLGGGAASSMDTGTNDASLDFNSVQRGNPEIERRAQEVIDRCWQLGDQNPIISIHDVGAGGLSNAFPELVNDAGRGAVFELREVPLEEHGLTPLQIWCNESQERYVLSILEKDLDTFRAICERERCPFAVVGTATDDGHLKVRDDLFSNNPVDLPLNVLLGKPPKTTRTDKTVTPSKKPFHAGDIDITEAAYRVLRLPAVAAKNFLITIGDRSVGGMTHRDQMVGKYQTPVADCAVTMMGFNTYRGEAMSMGEKPAVALFDAPASGRMCVGEAITNIAAVNIGDIGNIKLSANWMAACGNEGEDEKLYRTVEAVSKACQALDLSIPVGKDSLSMKTVWQDGEEKKSVVSPLSLIISAFAPVKDVRKTVTPELKNVEGSVLLFIDLGFGKARMGGSAFGQVYNNMSGDAPDLDDAGRLKAFYSVIQQLVAEDKLLAYHDRSDGGLFATLAEMAFAARCGISADIDCLMDKFLPIHLPDFQGDPAEDLSDELYNHAAIKILFNEELGAVIQIRQKDRDYVDAAFETAGLTDAVSRIGSPDFDNEFISFFGYGYFLEQNRADLQRAWQETSHAIQRLRDNPACADSEFALIGDNERSALFADVKFDVNEDIAAPFINSGAKPKIAILREQGVNGQIEMAAAFTRAGFDAYDVHMSDLMAGRFRLADFKMLAACGGFSYGDVLGAGEGWAKSILFHPALRDQFAAFFADPNTLTLGVCNGCQMVSNLAEIIPGAETWPKFKRNLSEQFEARLNMVHVPKSASLILNEMQDSSLPVVVSHGEGRADFALHGGNISADLGIALQYVDGQNQVTQTYPLNPNGSPQGIAGITNADGRVTIMMPHPERVYRAAQMSRKPEGWTELSGWYRLFAGARKALG
What is the function of this protein?
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase, FGAM synthase, FGAMS, Formylglycinamide ribonucleotide amidotransferase, FGAR amidotransferase, FGAR-AT.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_STREM
Sequence: MKLHELKPAKGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGGGVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNAFEDGTEVTPVVLKEAGIVRAEKSGVKILGNGELTKKLTVKAAKFSKSAEAAITAKGGSIEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: SELU_PSEP1
Sequence: MRPDCTDFRQLFLDDVPMMDMRAPVEFAKGAFPGVVNLPLMNDQERQKVGTCYKQQGQAAAIALGHQLVSGTTKQARLEAWAAFAKAHPDGYLYCFRGGLRSQIVQGWLRDEAGIQYPRVKGGYKAMRTFLLETTQQAVEQCDFVLVGGLTGTGKTDVLHQLDNVLDLEGHANHRGSSFGKRATAQPAQIDFENQLAIDVLKKRARGIGQFVLEDEGRIVGSCTVPLELYQGMQHYPLVWLEDSFTNRVERILRDYVVNLSAEFKAVHGEEDGPRLFAERMLQSMANIYKRLGGERHQRLSEMLREALQEQQRSGAVDLHRGWIEGLLNEYYDPMYAYQRAAKAERIEFAGDAVEVREYLKARALREPRK
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: FETP_SALEP
Sequence: MSRTIFCTYLQRDAEGQDFQLYPGELGKRIYNEISKDAWAQWQHKQTMLINEKKLNMMNAEHRKLLEQEMVSFLFEGKDVHIEGYTPEDKK
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: TM38A_RAT
Sequence: MDLISSLSLGELALSFSRVPLFPVFDLSYFIVSIIYLKYEPGSVELSRRHPVASWLCAMLHCFGSYILADLLLGEPIIDYFSNSSSILLASGVWYLIFFCPLDLFYKCVCFLPVKLIFVAMKEVVRVRKIAVGIHHAHHYHHGWFIMIATGWVKGSGVALLSNLEQLLRGVWKPETNEILHMSFPTKASLYGAILFTLQQTRWLPVSKASLIFVFTMFMVSCKVFLTATHSHSSPFDVLEGYICPVLFGATWGGDHHHDNHGAPHGMGLGTQHSGLPAKAKEELSEGFRKKKTKKAD
What is the function of this protein?
Monovalent cation channel required for maintenance of rapid intracellular calcium release.  May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.
What are the official names of this protein?
Trimeric intracellular cation channel type A, TRIC-A, TRICA, 27 kDa sarcoplasmic reticulum protein, SPR-27, Transmembrane protein 38A.
What is the protein family that this protein belongs to?
Belongs to the TMEM38 family.
What are the subcellular locations of this protein?
Sarcoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane.
Protein: CYB_AKOFU
Sequence: MKILRKNHPLLKIINHSFIDLPTPSNISSWWNFGSLLGMCLMIQILTGLFLAMHYTSDTTTAFSSVAHICRDVNYGWLIRYLHANGASMFFICLFIHVGRGIYYGSYALSETWNIGIILFLMTMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGSTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAAFALVHLLFLHETGSNNPSGLNSDSDKIPFHPYYTTKDLLGIFLLLLVLMILALFFPDVLGDPDNFTPANPLNTPAHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAAFPLLNTSKQHGLIFRPVTQVIYWIFIANLLVLTWIGGQPVEYPFTMIGQIASITYFAIITILMPISNTIENNIIKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MNMA_BACP2
Sequence: MTKRPEDTRVVVGMSGGVDSSVAALMLKEQGYDVIGIFMKNWDDTDENGVCTATEDYEDVIRVCNQIGIPYYAVNFEKQYWDKVFQYFLDEYKAGRTPNPDVMCNKEIKFKAFLEHALSLGADYLATGHYARVDRTGDEVKMLRGLDANKDQTYFLNQLTQEQLDKVMFPIGDLEKKRVRELAKEAELATATKKDSTGICFIGERNFKTFLSQYLPAQPGVMQTMDGEVKGEHDGLMYYTIGQRQGLGIGGSGDPWFVVGKDLEQNILFVEQGFHNPLLYSESISAVNISWTRPHIVGENGELTCTAKFRYRQEDHHVKVKMTGEQEAMVIFDEPVRAVTPGQAVVFYDGDECLGGGTIDDVFKDGQKLSYV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DYC1_CAEEL
Sequence: MPVRKKHGPYDIIADDVYDCRIPLHNELAYQHGIHFEAKYVGSMEIPRPGTRIEIVAAMRRVRYEFKARGIKKRPVDITVSVDGVKVVLQRKKQKEKGLSWDESKLLVMFHPIYRIFYVSHDSQDLQIFSYIARDGASNTFKCNVFKCSKKSQAMRVVRTIGQAFEVCHKVAQDQMQEKHEDEAAKSKISMQSEDEAGPNALDVIEERGGREEDSRSSSPMEAPPVGGPLYGKRLSLFQPRKPSTTSSSGGTAIDTTAIPENVLEIPNTSHPILQPKAPELVPQLQPQTALPYQQKPQSLLNIQQQQFNTLPSQMPSTQTLPSLSENPGQSHIPRMMTMPPNMPYPTATLPHPRTWAPQIPSYPNSMQSLEQNVPMYYPQMPGMLPSSSSLPFGLSSPVMVSPYATLQLNMQSQQLDQPDHSGSQITMDQYNQQLMRSQLDQAQQSVQVAGCQVQLLRDQLTSETTARLEAQSRTHQLLSANRDLLEQVQNLVSRLQMLETKITSEIHHSSSQPPQHQPIYQPSTSTPLNPKMPLSIDHNDPRIPGNSSIRLNYPYQVQPLADLRAGSLPPVKESKERRKDEGTRTEPESNAEDTTDYSSSDQYERTSNVMKPSHFNILMSNPLVDINVPSGAAMSSRMEQFDMGDTPGTSSTPPKKEKKPSSGILRGENFSRMSFNPKLGREKEREQQQLMFEDTLEDDSPRSIPPSPPSKARNTTIDSLFKPQDDPPTIADREPQQLPPQPSQQNQKKNTAVNLLMPTMPASSSLVTAMYPPMRQPAVPVNKIQPKVDVFRKKTLKTLSMDIAEEPEPSEMDPNRNNLPSSTNSSMKRRGFLPPPNTDVEIKEIEDYINRNVDRSKLPETSLLTRLTRQAQGDNSLGNLPNGYPQ
What is the function of this protein?
Together with dys-1 and hlh-1, participates in a common muscular function.
What are the official names of this protein?
Dystrophin-like protein 1, Dyb-1-binding and CAPON-related protein.
Protein: METE_STRSY
Sequence: MTTTIIGFPRIGEHRELKFITEKYFRNEIPQEELLEAAKDLRAKHWNIVKEAGITEIPSNDFSHYDNVLDAAVLFNIIPKAVQDLELTDLEKYFALARGYQGEKGDVRARPMKKWFNTNYHYIVPAIEKDTEIKLAGHKIFDEFQEAKNLGITTRPVLIGPFTLLQLTDFEEGLTATNFADSLVAAYGQVFEKLAELGAEKIQLDEPSLVKDLTAEEKALFLRIYQTLLADKKGLQVLIQTYFGDVRDIYTELTSLPVDAIGLDFVEGKETAALVATGFPADKTLYAGIVNGKNIWRNNYEKSLAVLDAIPAENVVITTSCSLLHVPFTTANEEFEPAILNHFAFAVEKLSELRDLDAIRNGQGEVALTANKELFALERVGRDAALADRLAGLTDTDYTRLPVFAERESIQREKLNLPLLPTTTIGSFPQTKEVRSTRLAFRKGNISEEEYDAFVKTQTDEWIAWQEEVDFDVLVHGEFERNDMVEYFGENLSGYLFSKNGWVQSYGMRGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKESTLQIALAIKEEVLDLEAAGIKIIQIDEAALREKLPLRRSDWYSEYLDWAIPAFRLVHSTVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLVILDELKAKNFQTQVGPGVYDIHSPRVPAVDEIAHTIQAILAKVPKEKVWINPDCGLKTRGESETKASLIHLTQAAKAARKEL
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: RLMD_IDILO
Sequence: MAQFFKPQKRNKSVSKTLKGQVSALDHQARAVVRAAVKGQSTRFIMGALPGEVIEYKTAGKHSGHLERILEPSSDRREVPCEYYASCGGCDFQHIDEQKQLAHKRQVVEELFQKFGVFNPQTSSLPWQEPLVSEPMRYRRRVRLATRWLGKEQKLLIGFREAQSHHIVPIEDCLVADEILLHCVNTLYPLLNTSTVASKLGHIEAINTNTPVILLRITEALPGDAMQALQEWQTVNKTNIWLQSENDLQPLAGAAMPFDTSIDGDKLYFQPGDFLQVNGGINQRMVQQAMDWLKPEKTQRVYDFFAGIGNFSLPLARRAQSVLAVEGVYRMAEQTRINAESNGMDNLSSLSADLNEITASDLGKPADLWCLDPARPGAEGVVKLLHKLKPEHRPQRILYVSCAPDTLARDIAGMLTESKGCNYRIIGLSTVDMFPQTHHIETMVCLERAS
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: NUOK_CITK8
Sequence: MIPLQHGLILAAILFVLGLTGLVIRRNLLFMLIGLEIMINASALAFVVAGSYWGQTDGQVMYILAISLAAAEASIGLALLLQLHRRRQNLNIDSVSEMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LGT_YERPE
Sequence: MSNSYLAFPKFDPVIFSIGPVSLHWYGLMYLVGFVFAMWLAVRRANKPGSGWTKEEVENLLYAGFLGVFIGGRVGYVLFYNLPMFLDNPLYLFKVWDGGMSFHGGLIGVICVMLWFARRTKRNFFQVADFIAPLIPFGLGAGRLGNFINAELWGRVTTDTPWAMLFPTSRNTDIAIVAADPAKWQAIFNQYGVLPRHPSQLYEMILEGVVLFIILNVFIRKPRPMGSVSGLFLIGYGTFRIIVECFRQPDEQLGLFEGMISMGQILSVPMILAGIIMMIWAYRRPTQKLS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y179_ARCFU
Sequence: MAGRVQEIVCRGGWMRAVVVLRDEIEPSFDAEEIHLLVLENGTGGRAISEKGEMRAMARDKIRAIRRAEKLFERFEEFYNVSGLSIAFDRFEDELIHAVESLGAEVVYFFTSMPLPERLLSENVTLVFPRGGLSFNKALYVHSSSTPNTAWLERAKELFILAIVQPTMPPEASSRKFREEFERMERETEELSSHLKAERAVIRGNIVEDTLRYSEKHGADTIFLNRGLGKENIEKIVERAKASVVVV
What are the official names of this protein?
Uncharacterized protein AF_0179.
Protein: AMELX_MOUSE
Sequence: MGTWILFACLLGAAFAMPLPPHPGSPGYINLSYEKSHSQAINTDRTALVLTPLKWYQSMIRQPYPSYGYEPMGGWLHHQIIPVLSQQHPPSHTLQPHHHLPVVPAQQPVAPQQPMMPVPGHHSMTPTQHHQPNIPPSAQQPFQQPFQPQAIPPQSHQPMQPQSPLHPMQPLAPQPPLPPLFSMQPLSPILPELPLEAWPATDKTKREEVD
What is the function of this protein?
Plays a role in the biomineralization of teeth.  Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development.  Thought to play a major role in the structural organization and mineralization of developing enamel.
What are the official names of this protein?
Amelogenin, X isoform, Leucine-rich amelogenin peptide, LRAP.
What is the protein family that this protein belongs to?
Belongs to the amelogenin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: NU4LM_MONMN
Sequence: MTMVYANIFLAFITSLMGLLMYRSHLMSSLLCLEGMMLSLFVMMTVTILNNHFTLANMAPIVLLVFAACEAALGLSLLVMVSNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYM_META3
Sequence: MNNKYLLTTALAYTNGPLHLGHARSTYIPADIIKRYLKLKGNDVIHVGGTDNHGVPITLTAEKEGVKPEDIVNKYHNEIKRDLDNLSVEFDSYGKTHSDTHIQNAQEFYKKLKENGYIYEKEIEQFYCPDCDKFLADRYVEGSCPFCEGEARGDHCEVCGRHLEPTELVNPYCVICNATPQLKKTTHYFFKLSALSDNLDNYVKNSNMPDHIKNMAYSWIRELHDWDISRGIKWGVPIPDDENQVMYVWLEAPIGYISFTKMMGDIWKEYWLKNNDNNTENQNTKIWHFIGKDITVHHAVFWPGMLLGHGEYNLPNSIFSGGYLTLEGKKMSTSKKWVVWVDDFIKYFDSDYLRYFLMANAPLNRDCDFSFDEFQKRINTELIAIIANFTHRALVFSHRKFGALPVIDKPEEELNKEDLALLDKCSETIEKYNKNMMDCNLKDALVDIIHLAKEGNNYFQKMEPWTVDDENRLKQIMFVCGVITKHIAYLLYPFMPNKTNELLDLMNEEMDLEIRGNELKKPIVVFSKIENDTIKMVKEKLLKSENSKNTKNKKKNTKKNKNGEKMELIGIDDFAKIELKVAQILEAEEVPKSKKLLKLIVDIGDEKRQVVAGIKGHYTPEELIGKKIVLVCNLKPAKLCGVESQGMVLAAGDEEVALLSPEKDLPVGSTIC
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BLO2_KLEOX
Sequence: MIKSSWRKIAMLAAAVPLLLASGALWASTDAIHQKLTDLEKRSGGRLGVALINTADNSQILYRGDERFAMCSTSKVMAAAAVLKQSESNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGPEKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRAQLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLVLVTYFTQPQQDAKNRKEVLAAAAKIVTEGL
What is the function of this protein?
Hydrolyzes broad-spectrum beta-lactam antibiotics.  Active against all third-generation cephalosporins but ceftazidime.
What are the official names of this protein?
Beta-lactamase OXY-2, Penicillinase.
What is the protein family that this protein belongs to?
Belongs to the class-A beta-lactamase family.
Protein: FIP1_YARLI
Sequence: MDDDDDFLYGTEEPAVKRARVEPEGAEDDEEPHSQTTKQQEPEDDSDSEYESDDSDIDIVIDTGAPSKLASTASAAAKKEAPAASSAAPEASDTPKEESASEERPQPAAKMPGIDIEKVGMLDGKPITEHNLEDFEDKPWRMPGADITDYFNYGFDEFTWMAYCDKQNQIRGEYNPQNMMAMMGMSMMGMPGMPGGGQMPMPGGEGMPDMFKMMQGMNPPK
What is the function of this protein?
Pre-mRNA polyadenylation factor that directly interacts with poly(A) polymerase.
What are the official names of this protein?
Pre-mRNA polyadenylation factor FIP1.
What is the protein family that this protein belongs to?
Belongs to the FIP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUTF_ECOSM
Sequence: MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHATPYGLVWFDRSYHALMRPAC
What is the function of this protein?
Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.
What are the official names of this protein?
FMN reductase (NADH) RutF, FMN reductase, NADH-flavin reductase RutF, NADH:flavin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
Protein: HDA11_HUMAN
Sequence: MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSMLVEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGGTIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVERNIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVTSGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
What is the function of this protein?
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.  Histone deacetylases act via the formation of large multiprotein complexes.
What are the official names of this protein?
Histone deacetylase 11, HD11.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MTNN_MYCBO
Sequence: MAVTVGVICAIPQELAYLRGVLVDAKRQQVAQILFDSGQLDAHRVVLAAAGMGKVNTGLTATLLADRFGCRTIVFTGVAGGLDPELCIGDIVIADRVVQHDFGLLTDERLRPYQPGHIPFIEPTERLGYPVDPAVIDRVKHRLDGFTLAPLSTAAGGGGRQPRIYYGTILTGDQYLHCERTRNRLHHELGGMAVEMEGGAVAQICASFDIPWLVIRALSDLAGADSGVDFNRFVGEVAASSARVLLRLLPVLTAC
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.