PharMolix/UniProtQA huggingface dataset:
Protein: DNAJ_BACCZ
Sequence: MSKRDYYEVLGLSKGASKDEIKKAYRRLAKKYHPDVSKEENAIEKFKEVQEAYEVLSDDQKRAQYDQFGHAGANQGFGGFGGGGDFGGGFGFEDIFSSFFGGGGGRRRDPNAPRQGADLQYQVTLDFEEAIFGKELNVEIPVEDPCDTCKGSGAKPGTSKETCKHCSGSGQVSVEQNTPFGRIVNRQACSHCSGTGQMIKEKCTTCHGSGKVRKRKKINVKIPAGIDNGQQIRVSGKGEAGVNGGPAGDLYVVVHVRSHEFFEREGDHIICEMPLTFAQMALGAEVEVPTVHGKVKLKIPAGTQTGTEFRLKGKGAPNVRGYGQGDQYVVVRVVVPTKLTSHQKDLLREFAGQEEQDDSLFGKLKRAFKGE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMED1_MOUSE
Sequence: MMAAGAAVALALWLLLPAVGVGEAGPPPIQDGEFTFLLPAGRKQCFYQSAPANASLETEYQVIGGAGLDVDFTLESPQGVLLVSESRKADGVHTVEPTEAGDYRLCFDNSFSTISEKLVFFELIFDSFQDEEEVEGWAEAVEPEEMLDVKMEDIKESIETMRTRLERSIQMLTLLRAFEARDRNLQEDNLERVNFWSAANVAVLLLVAVLQVCTLKRFFHDKRPVPT
What is the function of this protein?
Potential role in vesicular protein trafficking, mainly in the early secretory pathway.  May act as a cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and may be involved in vesicle coat formation at the cytoplasmic side.  Plays a positive role in IL-33-mediated IL-8 and IL-6 production by interacting with interleukin-33 receptor IL1RL1.  Plays also a role in the modulation of innate immune signaling through the cGAS-STING pathway by interacting with RNF26.
What are the official names of this protein?
Transmembrane emp24 domain-containing protein 1, Interleukin-1 receptor-like 1 ligand, Putative T1/ST2 receptor-binding protein, p24 family protein gamma-1, p24gamma1.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein.
Protein: AROA_RUMCH
Sequence: MFLKVQKSDISGSISIPGSKSHTIRSLFLAGLAKGTSVIRNPLLSTDAVSGVNVCRAFGSTYDLNNESYVVNGMGACPQVPENVIDVGNSGTSLRLGLMTAALVDGYTVFTGDYQIRKRQIGPLVEAINNLGGKAFTTRGNESAPVVIKGRATGGYTKLDCVTSQYLSSILLNTPLLEKDTHVEITRLNEIPYVEITLWWLDKLGIKYSHNSMKEFFIPGGQQYRPFECTIPGDFSSATFFMVQAAISERELVLTNLDMSDPQGDKAVLDILADMGAEIKYDHNNIKIKGKSLKGREIDMNSIPDALPAMAVAACFAKGETRLVNVPQARLKETDRISVMCSELTKMGADISELPDGLVIRESKLHGAAVKGYDDHRIVMSLAIAGLNCSGETVIDTAEAMNVTYPGFVESVKSCGGKIELI
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTND_KLEOX
Sequence: MSALTIFSVKDPQNSLWHSTNAEEIQQQLNAKGVRFERWQADRDLGAAPTAETVIAAYQHAIDKLVAEKGYQSWDVISLRADNPQKEALREKFLNEHTHGEDEVRFFVEGAGLFCLHIGDEVFQVLCEKNDLISVPAHTPHWFDMGSEPNFTAIRIFDNPEGWIAQFTGDDIASAYPRLA
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: GSA_MANSM
Sequence: MTDSNTLFSRAQQVIPGGVNSPVRAFKGVGGTPVFIQKAKGAYIWDTDDKQYVDYVGSWGPMILGHNHPAILSAVIKTAENGLSFGAPTPIEIDLAELVCKLIPSMEMVRMVSSGTEATMSAIRLARGYTNRDKIIKFEGCYHGHADSLLVKAGSGALTLGQPNSPGVPADFAKHTLTCTYNDLESVKQAFEQYPQDIACIIVEPVAGNMNCVPPQNNFLQGLRELCNQYGAVFIIDEVMTGFRVALGGAQSYYNVEPDLTCLGKVIGGGMPVGAFGGKKEIMQFIAPTGPVYQAGTLSGNPIAMAAGLACLTELQKAGNQERLAQLTEKLALGLKALADKHHVPFTVNYVGGMFGLFFTDKAQVTCYQDVMACDTEKFKVFFHKMLDEGVYLAPSAFEAGFMSLAHTDADIDRTLTAADKAFAALA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IFNG_EQUAS
Sequence: MNYTSFILAFQLCAILGSSTYYCQAAFFKEIENLKEYFNASSPDVGDGGPLFLDILKNWKEDSDKKIIQSQIVSFYFKLFENLKDNQVIQKSMDTIKEDLFVKFFNSSTSKLEDFQKLIQIPVNDLKVQRKAISELIKVMNDLSPKANLRKRKRSQNPFRGRRALQ
What is the function of this protein?
Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation.  Primarily signals through the JAK-STAT pathway after interaction with its receptor IFNGR1 to affect gene regulation.  Upon IFNG binding, IFNGR1 intracellular domain opens out to allow association of downstream signaling components JAK2, JAK1 and STAT1, leading to STAT1 activation, nuclear translocation and transcription of IFNG-regulated genes.  Many of the induced genes are transcription factors such as IRF1 that are able to further drive regulation of a next wave of transcription.  Plays a role in class I antigen presentation pathway by inducing a replacement of catalytic proteasome subunits with immunoproteasome subunits.  In turn, increases the quantity, quality, and repertoire of peptides for class I MHC loading.  Increases the efficiency of peptide generation also by inducing the expression of activator PA28 that associates with the proteasome and alters its proteolytic cleavage preference.  Up-regulates as well MHC II complexes on the cell surface by promoting expression of several key molecules such as cathepsins B/CTSB, H/CTSH, and L/CTSL (By similarity).  Participates in the regulation of hematopoietic stem cells during development and under homeostatic conditions by affecting their development, quiescence, and differentiation (By similarity).
What are the official names of this protein?
Interferon gamma, IFN-gamma.
What is the protein family that this protein belongs to?
Belongs to the type II (or gamma) interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: CLPP_HORVU
Sequence: MPIGVPKVPYRIPGDEEATWVDLYNVMYRERTLFLGQEIRCEITNHITGLMVYLSIEDGISDIFLFINSPGGWLISGMAIFDTMQTVTPDIYTICLGIAASMASFILLGGEPAKRIAFPHARIMLHQPASAYYRARTPEFLLEVEELHKVREMITRVYALRTGKPFWVVSEDMERDVFMSADEAKAYGLVDIVGDEMIDKHCDTDPVWFPEMFKDW
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: ACPW_STRCO
Sequence: MTDQQLDYQVTVEELSALMKRTAGVHVDPVTLRQQADDGFDTFGLDSLGLLGIVAELEKRYGLGLPEQAERCKTPADFLALVNGALKTGV
What is the function of this protein?
Involved in developmentally regulated synthesis of a compound biosynthetically related to polyketide antibiotics which is essential for spore color in Streptomyces coelicolor.
What are the official names of this protein?
Probable acyl carrier protein, ACP, WhiE ORF V.
Protein: GUN6_ORYSJ
Sequence: MLAASLRVEAVAVVAAAVLVLLLSPAAVVVVAGQHDYGDALHKSILFFEGQRSGRLPPDQRLRWRRDSGLHDGAAASVDLTGGYYDAGDNVKFGFPMAFTATLMSWGLIDFGRSFGPHKEEARKAVRWATDYLMKATAKPNTVYVQVGDAFRDHSCWERPEDMDTPRTVYKVDPSHPGSDVAAETAAALAAGSIVFRDADPAYSKRLLDRAIAVFEFADKYRGPYSSSLHDAVCPCYCDFSGYKDELLWGAAWLHKASRRREYREYIKKNEVVLGASESINEFGWDNKHAGINVLISKEVLMGKDEYFQSFRVNADNFMCSLLPGISNHPQIQYSPGGLLFKVGGSNMQHVTSLSFLLLAYSNYLSHAGARVSCGAGGSASPTQLRRVAKRQVDYILGDNPLRMSYMVGYGARFPRRIHHRGSSLPSVAAHPARIGCKGGAAYYASAAPNPNLLVGAVVGGPSDATDAFPDARAVFQQSEPTTYINAPLMGLLAYFSAHPNPAEWADD
What are the official names of this protein?
Endoglucanase 6, Endo-1,4-beta glucanase 6, OsCel9E.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 9 (cellulase E) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRB_FLAPJ
Sequence: MKELSVNNLLGIKYINENDINLVFETADHFKEVINRPIKKVPSLRDITIANIFFENSTRTKLSFELAQKRLSADVINFAASSSSVTKGETLVDTVNNILSMKVDMVVMRHASPGAAVFLSKNVKASIVNAGDGAHEHPTQALLDAYTIREKLGDVAGKKIVIVGDILHSRVALSNIYSLQKLGAEVRVCGPKTLIPKYIEALGVKVEPNLRKALEWCDVANMLRVQNERLDISYFPSTREYAMQYGLDKNLLDSLNKEIVIMHPGPINRGVEITSDVADSRQSVILNQVENGVAVRMAVIYLLASKIK
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RL24_PROA2
Sequence: MKTANKQTKLHVRKNDTVVVIAGNDKGKTGKVLKAYPQACRVIVEGVNIRKRHVRPSQSHPQGAIIEREFPIHASNVKKG
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: KHSE_NITEC
Sequence: MSVFTPVTKKQLAVWLQNYSLGSLTDLQGISSGIENTNYFVTTTQGKFILTLFEKLTSTELPFYLNLMAYLSEQGIPCPKPIESQDHALLGTLNGKPASIVSFLPGQSMTQIREEQCAQVGEILAKMHLAGLNYNGKNRNPRGLDWWQTAAGTVMPFLSRSEQSLLDEELQFQIKQRTTNLPQGIIHADLFRDNVLFTSTGIGGIIDFYFACNDALLYDLAITANDWCTLGDGVMDKARMHALVKAYQAARPLTAEEYPAWPAMLRAGALRFWLSRLYDYYLPRPGELTHKKDPEYFRKILEYHLTNPSVLPSLQA
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: RL17_PODCA
Sequence: MGKYSIDPENPIKSCKARGSYLRVHFKNTRETAQAIKKMHIRKAYRYLKDVIAKKQIIPFRRFCGGVGRKAQAKAFKHTQGRWPVKSAEFLLGLLKNAESNADVKGLDVDSLVIDHIQVNRAPYMRRRTYRAHGRINPYMSSPCHIEMIVSEKEQVVPRAEEEVEVKKVSKKKLAREKLKARE
What are the official names of this protein?
60S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: DDI2_XENTR
Sequence: MLITVYCVRRDLSEVTFSLEVDGDFELENFRALCELESGIPASETLIVYAERPLTNNQRSLASYGLKDGDVVILRQRETPEARPAAPFPGLDFSTIAVPGSSSQPAPSQPQAPPPPPPDTSSFPQGLDNPALLREMLLANPHELSLLKERNPPLAEALLSGDLEKFTKVLLEQQQERARREQERIRLYSADPFDLEAQAKIEEDIRQQNIEENMTIAMEEAPESFGQVVMLYINCKVNGYPVKAFVDSGAQMTIMSQACAERCHIMRLVDRRWAGIAKGVGTQKIIGRVHLAQVQIEGDFLPCSFSILEEQPMDMLLGLDMLKRHQCSIDLEKNVLVIGTTGTRTSFLPEGELPECARLAYGPGREEVRPEEIADRELAEVLQKSAEEADQQKP
What is the function of this protein?
Aspartic protease that mediates the cleavage of NFE2L1/NRF1 at 'Leu-104', thereby promoting release of NFE2L1/NRF1 from the endoplasmic reticulum membrane.  Ubiquitination of NFE2L1/NRF1 is a prerequisite for cleavage, suggesting that DDI2 specifically recognizes and binds ubiquitinated NFE2L1/NRF1.  Seems to act as a proteasomal shuttle which links the proteasome and replication fork proteins like RTF2.  Required for cellular survival following replication stress.
What are the official names of this protein?
Protein DDI1 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the DDI1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Chromosome.
Protein: RBSD_SHIF8
Sequence: MKKGTVLNSDISSVISRLGHTDTLVVCDAGLPIPKSTTRIDMALTQGVPSFMQVLGVVTNEMQVEAAIIAEEIKQHNPQLHETLLTHLEQLQKHQGNTIEIRYTTHEQFKQQTAESQAVIRSGECSPYANIILCAGVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_WOLPM
Sequence: MGRAIGIDLGTTNSCVAIMQGKDTKVIENKEGARTTPSIVALTSSGERLIGAPAKRQATTNASNTFFATKRLIGRQYSDPEMKNLSVPYKVFAAKSGDAWVKTTDNKEYSPSQIGAFILQNMKEAAEAYLGEEVKDAVITVPAYFNDSQRQATKDAGKIAGLNVLRIVNEPTAAALAYGLDKKHGHTIVVYDLGGGTFDVSILEIGDGVFEVKATNGDTHLGGEDFDNGVVSYLLDEFKKSNGIDLKNDPMAMQRIKEAAEKAKIELSSAMETEINLPFITADASGPKHLNMKLTRAKLESLVNDLIERTMAPCKKALEDAGLSASQIGEVVLVGGMTRMPKVIEKVKEFFGKDPHRGVNPDEVVAIGAAIQAGIIQGDVRDVLLLDVTPLSLGIETLGGVFTPLIERNTTIPTKKSQVFSTAEDNQTAVTIKVHQGERKLAVDNKLLGQFSLEGIPPAPRGRPQIEVTFDIDANGIAHVSAKDKATGKEQKIRIQSSGGLSDNEINRMVKEAEEKAQEDEKRKKFIEVKNQADSLVHSTEKSLTEYGDKVSPEDRSAIENAVNELKEVSKSDNIDDADSIQQKVTNLSQLSMKLGEAMYQTSQQNSAENGFSSEGNPNDKEEKVVDSDYQDIDNKEENK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: DAPA_MYCBP
Sequence: MTTVGFDVAARLGTLLTAMVTPFSGDGSLDTATAARLANHLVDQGCDGLVVSGTTGESPTTTDGEKIELLRAVLEAVGDRARVIAGAGTYDTAHSIRLAKACAAEGAHGLLVVTPYYSKPPQRGLQAHFTAVADATELPMLLYDIPGRSAVPIEPDTIRALASHPNIVGVKDAKADLHSGAQIMADTGLAYYSGDDALNLPWLAMGATGFISVIAHLAAGQLRELLSAFGSGDIATARKINIAVAPLCNAMSRLGGVTLSKAGLRLQGIDVGDPRLPQVAATPEQIDALAADMRAASVLR
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_SHIBS
Sequence: MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQYDDGKIVGIDAVVLSTQHSEEIDQKSLQEAVMEEIIKPILPAEWLTSATTFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTEKVPSEQLTLLVREFFDLRPYGLIQMLDLLHPIYKETAAYGHFGREHFPWEKTDKAQLLRDAAGLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNX1_RAT
Sequence: MEKSKNFRIDALLAVDPPRAASTQSAPLALVTSLAATPSGPGRGGSGGGGTSSGASRSCSPASSEATAAPGDRLRAESPSPPRLLTAHCALLPKPGFLGAGGGGGAAGGPGTPHHHAHPGAAAAAAAAAAAAAAGGLALGLHPGGAQGGAGLPAQAALYGHPVYSYSAAAAAAALAGQHPALSYSYPQVQGAHPAHPADPIKLGAGTFQLDQWLRASTAGMILPKMPDFSSQAQSNLLGKCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKKAKEQAAQEAEKQKGSGGGAGKGGTEEKTEEELLGPPVSGDKASGRRLRDLRDSDPDEDEDDEEDHFPYSNGVGAHAASSDCSSEDDSPPPRPGGPGHQPLPQ
What is the function of this protein?
Transcription factor (PubMed:18539116).  Recognizes and binds to the regulatory elements of target genes, such as visual system homeobox CHX10, negatively modulating transcription (By similarity).  Plays a role in establishing motor neuron identity, in concert with LIM domain transcription factor LMO4 (By similarity).  Involved in negatively modulating transcription of interneuron genes in motor neurons, acting, at least in part, by blocking regulatory sequence interactions of the ISL1-LHX3 complex (By similarity).  Involved in pancreas development and function; may play a role in pancreatic cell fate specification (By similarity).
What are the official names of this protein?
Motor neuron and pancreas homeobox 1, Homeobox protein HB9.
Protein: PIRC1_MOUSE
Sequence: MSEEKPQQSAEEPEPGEPKAKPAPEEPEPGEPKAKPAPEEPEPGEPKAKPAPEKTSDYYRISEKLPVRFNNPGWFHGYGTKEAVSMYRTSNQTYGSRAPTVHEMPKVFYPSSNKFSRQHAAFGMFQSHNINVTLEKSLVTGPDNHITHYDRLNFHPSYNVNRPSICD
What is the function of this protein?
Microtubule inner protein involved in the attachment of outer dynein arms (ODAs) to dynein-decorated doublet microtubules (DMTs) in cilia axoneme (PubMed:34715025).  Functions at the initial step of left-right asymmetry specification of the visceral organs (PubMed:27305836).
What are the official names of this protein?
Piercer of microtubule wall 1 protein, Pierce1, p53-induced expression in RB-null cells protein 1.
What is the protein family that this protein belongs to?
Belongs to the PIERCE1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: RS3_SACD2
Sequence: MGQKVHPTGIRLGIVKKHTSTWYAGKAEYADKLNQDLQVRKYIQNALAHASVSRIDIERPANTARVTIHTARPGIVIGKKGEDVEKLRTELTKQMGVPVHINIEEIRKPDLDAALAAQSVAQQLERRVMFRRAMKRTVQNAMRQGAEGVKVQVGGRLGGAEIARSEWYREGRVPLHTLRADIDYATAEASTTYGIIGVKVWIFKGEIIGGIEEVEANQKKKGSK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RL16_LISW6
Sequence: MLVPKRVKYRREFRGNMRGRAKGGTEVAFGEYGLQAVEASWITNRQIEAARIAMTRYMKRGGKVWIKIFPHKSYTSKPIGVRMGKGKGAPEGWVSPVKRGKIMFEIAGVPEDVAREALRLAAHKLPVKTKIVKREEIGGEANES
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: SYW_BRUME
Sequence: MSTFKPLVFSGVQPTGNLHLGNYLGAIKRWVEVQKTEECIYCVVDMHALTVSPDPVELMQSTREVTAAFLAAGIDPKKSIVFNQSRVMQHAELAWVFNCVARIGWMSRMTQFKDKAGKDRENASLGLFAYPSLMAADILLYRATAVPVGEDQKQHLELTRDIAQKFNNDYSDRIASLGVGVDMKVGDEQVSGFFPLTEPMISGPAMRIMSLRDGTKKMSKSDPSDLSRINLIDDEDTITKKIRKAKTDSDGLPSEVDGLEGRPEADNLVGIYAALSSTTKEDVLKEFGGRQFSDLKASLADLAVARLSPITHEMRRLVADPAHIDSVLRDGGEQAGAIAEQTMRHVRDIVGWLQN
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_COLP3
Sequence: MASTSAASNELVSSTINTILPTLVDGLDLNQRQSHDFFQQVLQGNIDPALMASVLTALKIKGETPEEIAGAAIAIRAAATPFPERNKEDIVADCVGTGGDGANTINISTTAAVLAAACGLKMAKHGNRSVSSMSGSADLLEAFGVNLSMSPETANHCLAQTNLCFLYAPAYHSGFKYAGPVRKAMGIRTLFNILGPLVNPAKPNIMLLGVYTPELLMPMAQALQLTGVKRAFVVHGSGLDEIALHGNTQAIEINNGELIERTISPQDFGLKNYTLEEIKGGTPAENADIIRDILSGQGKDAHNAAVIVNCAALLYLHDKAESLTQAAQLATEVLASGKGLSTLLTLVKLSNQDVSSTQTELKADK
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: PLSX_STRP4
Sequence: MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIKQYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTGALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSFYAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVADVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLNYSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: Y2349_STAAR
Sequence: MLSQEFFNSFITIYRPYLKLTEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHND
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator SAR2349.
Protein: RUVB_ECOL5
Sequence: MIEADRLISAGTTLPEDVADRAIRPKLLEEYVGQPQVRSQMEIFIKAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEFYQVPDLQYIVSRSARFMGLEMSDDGALEVARRARGTPRIANRLLRRVRDFAEVKHDGTISADIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMATVRAWNHFGITPPEMP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.