PharMolix/UniProtQA huggingface dataset:
Protein: ENO_ASPFU
Sequence: MPISKIHARSVYDSRGNPTVEVDVVTETGLHRAIVPSGASTGQHEAHELRDGDKTQWGGKGVLKAVKNVNETIGPALIKENIDVKDQSKVDEFLNKLDGTANKSNLGANAILGVSLAVAKAGAAEKGVPLYAHISDLAGTKKPYVLPVPFQNVLNGGSHAGGRLAFQEFMIVPDSAPSFSEALRQGAEVYQKLKALAKKKYGQSAGNVGDEGGVAPDIQTAEEALDLITEAIEQAGYTGKIKIAMDVASSEFYKADVKKYDLDFKNPESDPSKWLTYEQLADLYKSLAAKYPIVSIEDPFAEDDWEAWSYFYKTSDFQIVGDDLTVTNPGRIKKAIELKSCNALLLKVNQIGTLTESIQAAKDSYADNWGVMVSHRSGETEDVTIADIAVGLRSGQIKTGAPCRSERLAKLNQILRIEEELGENAVYAGSKFRTAVNL
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_ECOLC
Sequence: MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVINLTPDKQHSDVVRTVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPEGAVDNGQLRDVNEAIRSHAIEQVGKKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: HEM11_ANADE
Sequence: MLVAVGLNQKGATVADREVLALPSEELLDALTAFQALDGVDEVAIVSTCYRVEIFAAARCPAAAELSLRHALEARAGRSLPLFELQGEEAFRHLVRVASSLESAILGEPQILGQVKDAFHRAAEAGAAGKELASVLSRALAAAKRVRTETAVGRAGVSWGNAAAALASKVLGPLAGRRVAVIGAGEMARLTAQHMRDERASVVVLNRTLANAEALAAEVGGEARPLDALEQELLRADVVVSAAPAAPAALAPAVMQRILHARRKRIVMVDLAVPRAIPAETGALPDVYLCDVDDLDRVMKAAMAERAQAAQHAERIADEEVQKFARAEAERRAAPLIQEMRSRASAIAREEVERTLRRLGEDPELAKRLDAMAGSIVSKILHAPSTRLRQAVCDGGANDPLVAAAVQIFDLSAAPAARGDAA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase 1, GluTR 1.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: YAJQ_ECO8A
Sequence: MPSFDIVSEVDLQEARNAVDNASREVESRFDFRNVEASFELNDASKTIKVLSESDFQVNQLLDILRAKLLKRGIEGSSLDVPENIVHSGKTWFVEAKLKQGIESATQKKIVKMIKDSKLKVQAQIQGDEIRVTGKSRDDLQAVMAMVRGGDLGQPFQFKNFRD
What are the official names of this protein?
UPF0234 protein YajQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: TIG_METNO
Sequence: MQVTETKSEGLMREFQVVLAAAELEDRLATELAGLKDKVQLKGFRPGKVPVAHLRRVYGRSIMADVVQNAVNEANQKILEENKLKLALEPRIEMPEDKAEIEKALDAKADLSFKVALEVMPTFDLVDHSDITLTKPVAAVADEEVDAALTRMAEQNRSYSDRPEGAAAETGDRVVIDFVGRIDGEVFQGGSAEDANLDLGSNTFIPGFEDQLLGAKAGEQRTVTVTFPQDYPAEQLAGKEAVFDVTVKAVQAPGEATIDDELAKTFGLESLDKLKEAVRTSLSAELDAQSRRRVKKALLDALDSRYAFDLPPTLVHQEFAAVWAQVENDLKSRGKSFEDEGTTEEKAQSEYRRIAERRVRLGLVLAQVGESADIKVPDEEVNQALIARLRQFPGREREVYDFYRKNPQAMAELRAPLFEEKVVDHVLGQVKLVEEPVSKEALFADDEDEAAPAAETASEAGASPETKTETSAA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: IF2_COLP3
Sequence: MADITVAELAKEIGTPVDRLVTQLADSGVNKSATDAISQDEKEALLGHLKKQHGDESEAKPNKLTLNRKTKSTLTMGHGSKAKSVNVEVRKKRTYVKRSEVEDEKLAEEAAKAEAEAAILAEADAKAKAEAAAKEAENEKGVAAAKAEVEAERKAEAKIEAAAKAKIAAVEKAKNVEQAPEKVAETEEAKKLRLAQEKETLAKVEAEAAAAAEAAKKLAEENEGRWKEQEAERKAKEKEVVHLTSSVYAQEAEDKSDSADESGRRRKKKKAPDRNARGRNSGRGKGKTLSSPQSLKHGFTKPVETKLQDIRIGETISVAELANKMSKKGAEVVKAMFKLGAMATINQVIDQETAALVAEDMGFEVVLVKENALEEAVLADRNDTGEEITRAPVVTIMGHVDHGKTSLLDHIREAKVADGEAGGITQHIGAYHVETGHGMITFLDTPGHAAFTAMRSRGAKATDIVVIVVAADDGVMPQTIEAIQHAQASEAPIIIAVNKMDKESADPDRVKSELSQHGVLSEEWGGEVQFCHVSAKTGLGIDELLDSILLQSEVLELTAVVDKMANGVVVESKLDKGRGPVATVLVQEGTLKQGDIVLCGLEYGRVRAMRDENGKTIQSAGPSIPVEIIGLSGVPISGDEATVVKDEKKAREVALFRQGKFRDVKLARQQKAKLENMFASMAEGDISEVNVVIKSDVQGSLEAISDSLLKLSTDEVKVKIIGSGVGAITETDATLAAASNAIVVGFNVRADASARKVIESENIDLRYYSVIYALIEEVKQAMSGMLAPEFKQEIIGLAQVRDVFKSPKIGAIAGCMVTEGVIKRSAPIRVLRENVVIYEGELESLRRFKDDVQEVRNGTECGIGVKNYNDVRVGDQIEVFETIEIKRSL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETN_LEPVR
Sequence: MDIVSLAWAALMVVFTFSLSLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SSAAL_STAA8
Sequence: MKKLAFAITATSGAAAFLTHHDAQASTQHTVQSGESLWSIAQKYNTSVESIKQNNQLDNNLVFPGQVISVGGSDAQNTSNTSPQAGSASSHTVQAGESLNIIASRYGVSVDQLMAANNLRGYLIMPNQTLQIPNGGSGGTTPTATTGSNGNASSFNHQNLYTAGQCTWYVFDRRAQAGSPISTYWSDAKYWAGNAANDGYQVNNTPSVGSIMQSTPGPYGHVAYVERVNGDGSILISEMNYTYGPYNMNYRTIPASEVSSYAFIH
What is the function of this protein?
Has weak lytic activity toward S. aureus cells.
What are the official names of this protein?
Probable autolysin SsaALP.
Protein: MNTP_DESOH
Sequence: MNTLTIFGIAVALAMDAFAVSIAAGVFLRSIGLRHYFRLAWHFGLFQALMPIVGWYAGLSVRGLIERYDHWIAFFLLAFVSFNMIRESFDAGENHTKADPTRGLRLVLLSIATSIDALAVGLSLSVLNVSVWMPATVIGITAAVFTVGGLMMGSRAGDIPWLRRYADRVGAGVLLFIGLRILYAHGVFY
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNAJ_BRUSI
Sequence: MKIDYYEALGVTRTADDKTLKAAFRKLAMQYHPDRNPDDPEAERKFKEIGEAYETLKDPQKRAAYDRFGHAAFENGGMGGGFGNGFGGAGGFADIFEDIFGEMMGGGRRRSNGGRERGADLRYNMEVTLEEAYAGKTAQIRVPTSITCDECSGSGAKPGSQPTTCTMCSGSGRVRAAQGFFSVERTCPGCNGRGQIIKDPCEKCHGQGRVTQERSLSVNIPAGIEDGTRIRLAGEGEAGLRGGPAGDLYIFLSVKPHEFFQRDGADLYCKVPISMTTAALGGQFEVSTLDGTQTRVKVPEGTQNGKQFRLKGKGMPVLRQSVTGDLYIQIDIETPQNLSKRQRELLEEFEKLSSQENSPKSAGFFSRMKEFFEGIGE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPK5_ARATH
Sequence: MAKEIESATDLGDTNIKGVLVHGGRYFQYNVYGNLFEVSNKYVPPIRPIGRGAYGFVCAAVDSETHEEIAIKKIGKAFDNKVDAKRTLREIKLLRHLEHENVVVIKDIIRPPKKEDFVDVYIVFELMDTDLHQIIRSNQSLNDDHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNSNCDLKITDFGLARTTSETEYMTEYVVTRWYRAPELLLNSSEYTSAIDVWSVGCIFAEIMTREPLFPGKDYVHQLKLITELIGSPDGASLEFLRSANARKYVKELPKFPRQNFSARFPSMNSTAIDLLEKMLVFDPVKRITVEEALCYPYLSALHDLNDEPVCSNHFSFHFEDPSSTEEEIKELVWLESVKFNPLPSI
What are the official names of this protein?
Mitogen-activated protein kinase 5, AtMPK5, MAP kinase 5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Protein: RL23_NOVAD
Sequence: MANAIDTRHYDVIVAPHITEKATLLSENNAVVFKVADKATKPEIKAAVEALFNVKVTKVNTLTQKGKTKRWKGKPYKRTDVKKAVVTLAAGQSIDVTSGI
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: ENO2_DESHY
Sequence: MSYIEEIYGREILDSRGNPTVEVEVLLEDGSMGRAAVPSGASTGAFEAVELRDGDKGRFLGKGVLQAVANVNEVIAPELEGLNPFDQPAIDRELIALDGTENKGKLGANAILGVSLANAKAAAECVGLPLYQYLGGVNAKELPVPMMNILNGGQHADNNVDIQEFMIMPVGAKSFAEALQMGTEVYHSLKAVLKEKSLATAIGDEGGFAPSLESNADALLAIMDAIQRAGYTPGKDIALALDVAATELYRDGKYHLEGEGLTKTADEMIAYYEDLVEKYPIVSIEDGLSEEDWEGWKKLTEKLGSKIQLVGDDLFVTNPARLARGIKEKCANSILIKLNQIGTLTETLDAIEMAKRAGYTTVISHRSGETEDVTMAHVAVAVNAGQIKTGAPARTERVAKYNELLRIEEELGETGVYPGHEALGR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase 2, 2-phospho-D-glycerate hydro-lyase 2, 2-phosphoglycerate dehydratase 2.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: YIP6_SCHPO
Sequence: MLEILWANITPIQTFVSSNHLTMLYGLKRFGCRLYHHSKSTRYIDATAKVVSQEPAAISSTGAIPLNSPAAPLLSQDVLIVERQLEMMNVFLGYEQANRYVILNQQGQHLGYIAEQGASSILSSLSRQFFHTHRAFKADVMDSNGQLVLQLNRPFSWINSRLQIHSIDYSKFSSTLVGEVLQKWHLWRRRYELFLAKRSMFEQFAKIDERVLSWEFLLRNEQDRILGSVSRNFMGLPREFFTDTGNYVLRFTSTSAANGSVNENQLLQAAHGIANDVCARDMSLEERAVMLGSAVTIDFDYFSRIHGGPALGLNIPFMFGGSSSNHDYPAEDLSAQEILKNDQETTPSTNDSSSETKSPFLSDADLDQQDFWDIFDRDGDD
What are the official names of this protein?
Phospholipid scramblase family protein C343.06c.
What is the protein family that this protein belongs to?
Belongs to the phospholipid scramblase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LOVG_DROPS
Sequence: MTNNDAAVEAPSSSRASSSKQQPKLEITEKVRVLCLHGYRQDGDAFKNKLGSFRKFTSKYAEFVFISAPHIAAPLESAAEPVPEQRSWWANKDDGTFKGTNKGGPAFGFQDSLRLVEEAWKTQGPFQGLLGFSQGACFVGLICGLAKKKLTSIRPEFAVLSSGFVSGSLVHMSAYEEPVSIPTLHIYGSSDEIIPKDMSALLASHFKNVEVLEHGGGHYFPATAQQKQTYINFFQDRLQEYLEHLELQQSSSVSFIESGAEDNDDDGDANDAEVAAATAAAGSDLDDSD
What are the official names of this protein?
Esterase GA18864.
What is the protein family that this protein belongs to?
Belongs to the LovG family.
Protein: CH60_SHESR
Sequence: MAAKEVVFGNDARVKMLAGVNILANAVKVTLGPKGRNVVLDKSFGSPLITKDGVSVAKEIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIVTEGLKAVAAGMNPMDLKRGIDKAVAAAVIELKNLSQDCADSKAIAQVGTISANSDESIGEIIATAMEKVGKEGVITVEEGQALENELDVVEGMQFDRGYLSPYFINKPETGSVELDHPFVLLVDKKISNIRELLPILEGLAKTGKPLLIVAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDVAILTGGTVIAEEIGLELEKATLEDLGTAKRVVITKDNTTIIDGNGEQAQIEARVSQIKQQIEESTSDYDKEKLQERMAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVPGGGVALVRVASKIADVEVANEDQKHGVVIALRAMEAPLRQIATNAGEEASVVANTVKNGSGNYGYNAGNDTYGDMLEMGILDPTKVTRSALQFAASIAGLMITTEAMVAELPKADAPDMGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACDH_CHLAD
Sequence: MQADKVKVAILGSGNIGTDLMYKLLRQPGPMELALVAGIDPASEGLARARQLGIPTSASGIEAILADPEIRIVFDATSAKAHVRHARLLREHGRIAIDLTPAARGPYVVPPVNLGMHLDAPNVNLITCGGQATIPLVYAVSRVTPVRYAEMVSTVSSRSAGPGTRQNIDEFTFTTARGLEVIGGAHQAKAIIILNPANPPILMRNTIYVLPEGEFDETAVQNSVAQMVADVQQYVPGYRLKNRPVIERRATPWGERPVLIMLLEVEGAGDFLPRYAGNLDIMTSAARRVGEVFAQHILKEVAA
What are the official names of this protein?
Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: TOM20_PONAB
Sequence: MVGRNSAIAAGVCGALFIGYCIYFDRKRRSDPNFKNRLRERRKKQKLAKERAGLSKLPDLKDAEAVQKFFLEEIQLGEELLAQGEYEKGVDHLTNAIAVCGQPQQLLQVLQQTLPPPVFQMLLTKLPTISQRIVSAQSLAEDDVE
What is the function of this protein?
Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins.  Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore (By similarity).  Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases.
What are the official names of this protein?
Mitochondrial import receptor subunit TOM20 homolog, Mitochondrial 20 kDa outer membrane protein, Outer mitochondrial membrane receptor Tom20.
What is the protein family that this protein belongs to?
Belongs to the Tom20 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: PGK_STAA3
Sequence: MAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENV_SRV2
Sequence: MTLKDIPFWRVLLIFQTARVYAGFGDPREAITMIHQQHGKPCDCAGGYVNAAPTVYLAAVSCSSHTAYQPSDSLKWRCVSNPTLANGENIGNCPCKTFKESVHSSCYTAYQECFFGNKTYYTAILASNRAPTIGTSNVPTVLGNTHNLLSAGCTGNVGQPICWNPKAPVHISDGGGPQDKAREIAVQKRLEEIHKSLFPELRYHPLALPKARGKEKIDAQTFNLLTATYSLLNKSNPNLANECWLCLPSGNPIPLAIPSNDSFLGSNLSCPIIPPLLVQPLEFMNLINASCFYSPFQNNSFDVDVGLVEFANCSTTLNISHSLCAPNSSVFVCGNNKAYTYLPSNWTGTCVLATLLPDIDIVPGDAPVPVPAIDHYLHRARRAVQFIPLLVGLGITTAVSTGTAGLGYSITQYTKLSRQLISDVQAISSTIQDLQDQVDSLAEVVLQNRRGLDLLTAEQGGICLALQEKCCFYANKSGIVRDKIKRLQEDLEKRRKEIIDNPFWTGLHGLLPYLLPLLGPLFCLLLLITFGPLIFNKIITFVKQQIDAIQAKPIQVHYHRLEQEDNGGVYLRVS
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm (By similarity).
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. Both proteins are thought to be concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag (By similarity).
Protein: ATPF_STAAN
Sequence: MTETANLFVLGAAGGVEWGTVIVQVLTFIVLLALLKKFAWGPLKDVMDKRERDINRDIDDAEQAKLNAQKLEEENKQKLKETQEEVQKILEDAKVQARQQQEQIIHEANVRANGMIETAQSEINSQKERAIADINNQVSELSVLIASKVLRKEISEQDQKALVDKYLKEAGDK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Membrane raft; Single-pass membrane protein. Note=Present in detergent-resistant membrane (DRM) fractions that may be equivalent to eukaryotic membrane rafts; these rafts include proteins involved in signaling, molecule trafficking and protein secretion.
Protein: CARB_SYMTH
Sequence: MPRRQDVEKVLVIGSGPIVIGQAAEFDYAGTQACQALREEGLRVVLINSNPATIMTDRHVADRVYIEPITPEFVERVIARERPQGLLPTLGGQVGLNMAMQLEEAGVLARYGVRLLGTPLTAIRRAEDRAEFRALMKEIGEPVPESAIVTTPEEALAFGEEVGYPLIVRPAYTLGGTGGGIAHDREEMRDIVTRGLKLSPVTQCLVERSLLGWKEIEYEVMRDGAGNAITICSMENIDPVGVHTGDSIVVAPSQTLTDREHQILRSAALKIIDALGIEGGCNVQFALNPHAREYMVIEVNPRVSRSSALASKATGYPIAKVAAKIAVGLRLDEIRNPVTGTTYAAFEPALDYCVIKIPRFPFDKFTTADRTLGTQMKATGEVMAIDRTFPGALLKAVRSLETGRDGLFHPAVQALDDQALRERLRTPNDERLWAVAEALRRGVTVPEIHALSAIDPFFLDGIAAIVAMERELADGPLTAERMRRAKQLGFSDAAIGRIVGMDPLAVRRLRLEMGVRPVFKMVDSCAGEFPAATPYYYSCYDEENEAVSPPGRKAVVLGSGPIRIGQGIEFDYSAVHAAWELKAEGIQSIVINNNPETVSTDFDTSDRLYFEPLTLEDVLNVVEQEGDIEGVICQFGGQTAINLAVPLSRAGVRVLGTDIDQMDRAEDRRRFDQLLSDLSIPRPPGGTATSVEEAVAVARRIGYPVLVRPSFVLGGRAMEIVHDEAELRAYMREAIAVSSDRPVLVDRYFLGKEVEVDCVSDGEQVIIAGIMEHLERAGVHSGDSIAVYPTVTLTHRQRETIVAYSTRLALALQVKGLVNIQYVIHGGEIYVIEVNPRSSRTVPFLTKVTGLELAKVATQVIAGHTLAELGYDPDRSGAALVFRTPAGAGWLWPEPAERVAVKAPVFSWQKLTQVDTALSPEMKSTGEVLGVDADLPRALYKALLASGVRVPHRGTVLFTVADRDKAEAMGLARQFSDLGYRIVATTGTARALQACAIPAERVNKVSEGAPAIPDLIRAGKIDLVINTLTRGRDAHRDGFIIRRTAVEHGVPTLTSLDTARAVLTVLSSLREGEEVGISAVQDWV
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: THII_STAA8
Sequence: MKYDHLLVRYGELTLKGSNRKKFVNQLRNNVNKSLKGLDGFVVKGKRDRMYIELEDHADINEITYRLSKIFGIKSISPVLKVEKTIEAISAAAIKFAQQFEENSTFKIDVKRADKNFPMDTYELQRELGGAVLKHFDNISVNVKRPDHEIRVEVRLDAIYMYEEVVPGSGGLPVGTGGKTLLMLSGGIDSPVAGMEVMRRGVTIEAIHFHSPPFTSDQAKEKVIELTRILAERVGPIKLHIVPFTELQKQVNKVVHPRYTMTSTRRMMMRVADKLVHQIGALAIVNGENLGQVASQTLHSMYAINNVTSTPVLRPLLTYDKEEIIIKSKEIGTFETSIQPFEDCCTIFTPKNPVTEPNFDKVVQYESVFDFEEMINRAVENIETLEITSDYKTIKEQQTNQLINDFL
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPCKG_KORCO
Sequence: MLFDLKLLEDKRGKVSEIKGSIIKSLDILENKRIISVGDRVTRELLGSGRRPEVAIIDLKERREMNCSTIFYLDDYLILVARNPAGTLMREAWLKVRKAIEISLSGKNAAVIVDGEEDLLGFPAIILPPEGWVMVYGQPGVGMVSVNIDRKAREEAMNLLQEAFLPI
What is the function of this protein?
Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
What are the official names of this protein?
GTP-dependent dephospho-CoA kinase, Dephospho-coenzyme A kinase, DPCK.
What is the protein family that this protein belongs to?
Belongs to the GTP-dependent DPCK family.
Protein: ECM1_MOUSE
Sequence: MGTVSRAALILACLALASAASEGAFKASDQREMTPERLFQHLHEVGYAAPPSPPQTRRLRVDHSVTSLHDPPLFEEQREVQPPSSPEDIPVYEEDWPTFLNPNVDKAGPAVPQEAIPLQKEQPPPQVHIEQKEIDPPAQPQEEIVQKEVKPHTLAGQLPPEPRTWNPARHCQQGRRGVWGHRLDGFPPGRPSPDNLKQICLPERQHVIYGPWNLPQTGYSHLSRQGETLNVLETGYSRCCRCRSDTNRLDCLKLVWEDAMTQFCEAEFSVKTRPHLCCRLRGEERFSCFQKEAPRPDYLLRPCPVHQNGMSSGPQLPFPPGLPTPDNVKNICLLRRFRAVPRNLPATDAIQRQLQALTRLETEFQRCCRQGHNHTCTWKAWEGTLDGYCERELAIKTHPHSCCHYPPSPARDECFAHLAPYPNYDRDILTLDLSRVTPNLMGQLCGSGRVLSKHKQIPGLIQNMTIRCCELPYPEQACCGEEEKLAFIENLCGPRRNSWKDPALCCDLSPEDKQINCFNTNYLRNVALVAGDTGNATGLGEQGPTRGTDANPAPGSKEE
What is the function of this protein?
Involved in endochondral bone formation as negative regulator of bone mineralization.  Stimulates the proliferation of endothelial cells and promotes angiogenesis.  Inhibits MMP9 proteolytic activity (By similarity).
What are the official names of this protein?
Extracellular matrix protein 1, Secretory component p85.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: NUOD_DEHM1
Sequence: MAIKTESFILNIGPQHPSTHGVFRLRLILDGEVITDLEPVFGYLHRGIEKLAEGRTYLQDIPFTDRLDYLGSMTNNHAYVMAVEKLAGITVPERAEYIRVILDELQRIASHLAGLGFFLNDLGALQTPLLYMFREREKIVELFDMCSGQRLNYNYYRFGGFVQDLPEEFLPALKKLLDTLPGFIDEYEQLISTNEIVLIRTKGVGVLKRELAINSSAAGPVLRASGVNWDIRRNDPYSIYDRFEFDIPTAQNGDTYDRYMVRIREMRQSVRILRQAVKDLPEGEIMGKAPKLLKPPAGEVYSRIEGPKGELGFYLVSDGTDKPYRWRVRPPCLLNLSALKDMVVGWKVADLMAIFGSIDIVMGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.