PharMolix/UniProtQA huggingface dataset:
Protein: PTA_ACIAD
Sequence: MNTILMIPTGEGVGLTSACLGLIYALDCNGIKAGFLKPFSQELPNQVDRTTSLFSHLFQGKTVTSISHEKVLQRLALGERDELLEEAVSIHRNVAANYDVIIVEGLLPNAQDHFATELNAALAQALDAKVVLVSTADVQNPRRTAEKIEAHLHHFGGVSSNRTAGVLFMRTRGLPEETAQIPLTIDPSLRLNTEIAAFSQELQRYNRNLGTTTLPIIGLVPFSNTLSVPRTLDIASIIEGDWIHQGEARHRRILHSSLIASSIEYELNKFVAGELIISASERTDVLLASSLATSNGIPLAGLVLTERKAPNPQILDFCQHAIKQGLPILHTQLNTLETAQRLADFGNEIPVDDTERAEQVTRFVSSHIDTAWLNSQINTGVQPRLSPSAFRHELVQKSIAAKKRIVLPEGDEPRTVQAAAICQSRGIAHCILLAKPEAVVEVAKARGIELPDDLEIIDPDLIRNQYITPMVELRNGKLNELQAKEQLQDTVVLGTMMLALDQVDGLVSGAIHTTANTVRPAFQLIKTAPDYSLVSSVFFMLLPDEVYVYGDCAINPDPDADQLAEIAIQSADSAKAFGINPRIAMISYSTGTSGAGADVEKVAKATEIAKQRRPDLLIDGPLQYDAASVESVGRQKAPDSQVAGRANVFIFPDLNTGNTTYKAVQRSANVVSVGPMLQGLNKPVNDLSRGALVDDIVFTIALTAIQAEQQLEAKAAALAS
What is the function of this protein?
Involved in acetate metabolism.
What are the official names of this protein?
Phosphate acetyltransferase, Phosphotransacetylase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARAA_SALEP
Sequence: MTIFDNYEVWFVIGSQHLYGAETLRQVTQHAEHVVNALNTEAKLPCKLVLKPLGTSPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLSILNKPLLQFHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHSVVTGHWQDKEAHTRIGAWMRQAVSKQDTRQLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNAISDGDINALIDEYESSYTLTPATRIHGDKRQNVREAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAVEEKPILDVQHLGIGGKEDPARLIFNTQTGPAIVASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHHTVFSHALDLNDMRQFAEIHDIEIAVIDNDTRLPAFKDALRWNEVYYGFKR
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: ART10_YEAS7
Sequence: MAPKISISLNPPYNGEFYSSNDQMSGIVSLQLTKALSIRKISVILKGFSETLTKIDQEYMFQQNGMMMPGQDNKSFHTLMKFEQRVFPPDNVWNALDGSSKPFKVKPGSYNYSFQFDKFPRKPECLKNHTAKTVAFVTRSNARLPPTFNSHWQEFNKIDNLDLYFYSFGKVIYMVQVQIELGKSSSWFKPFHKLIREIETFEFIPEPKDLIIEPDEDDNEELNAFSNNSRGNSMVTNNEFFNSSNLKVPSKDVKVVNGVGYIKSDRNFSQANSILIENGDIRSRPVSSVTSTRQSTRLVNGMKVFPSTYKMGLPDGESNMRIEVRSRDLKQIYRKDYLFRSGSQNFDKVYVVMEGNIASLSKMQITPLKLQLNLLETTTYLSQGIANGNYSSLKLIEIDLNQLKSNKPLLDLNEIRENFDGSMFECELRLKDHPILRKLVFNEEDYRHRGNRLYSFKTCTIKRIFSLQLLIEWGINGIRKQSEVNIDPVQIFCQVREHVEAEALPRYVPPPTYTEMAS
What is the function of this protein?
May regulate endocytosis by recruiting RSP5 ubiquitin ligase activity to specific plasma membrane proteins in response to extracellular stimuli.
What are the official names of this protein?
Arrestin-related trafficking adapter 10.
What is the protein family that this protein belongs to?
Belongs to the ART10 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCAD_ECO7I
Sequence: MSTYTRPVMLLLSGLLLLTLAIAVLNTLVPLWLAQEHMSTWQVGVVSSSYFTGNLVGTLLTGYVIKRIGFNRSYYLASFIFAAGCAGLGLMIGFWSWLAWRFVAGVGCAMIWVVVESALMCSGTSRNRGRLLAAYMMVYYVGTFLGQLLVSKVSTELMSVLPWVTGLTLAGILPLLFTRVLNQQAENHDATSITSMLKLRQARLGVNGCIISGIVLGSLYGLMPLYLNHKGVSNASIGFWMAVLVSAGILGQWPIGRLADKFGRLLVLRVQVFVVILGSIAMLSQAAMAPALFILGAAGFTLYPVAMAWACEKVEHHQLVAMNQALLLSYTVGSLLGPSFTAMLMQNFSDNLLFIMIASVSFIYLLMLLRNAGHTPKPVAHV
What are the official names of this protein?
Uncharacterized MFS-type transporter YcaD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KFA_YEAST
Sequence: MSNTVRAISPDITLFNKTLTFQEISQNTREAVIYIHGGAWNDPENTPNDFNQLANTIKSMDTESTVCQYSIEYRLSPEITNPRNLYDAVSNITRLVKEKGLTNINMVGHSVGATFIWQILAALKDPQEKMSEAQLQMLGLLQIVKRVFLLDGIYSLKELLVEYPEYDCFTRLAFPDGIQMYEEEPSRVMPYVKKALSRFSIDMHLVHSYSDELLTLRQTNCLISCLQDYQLSFKLYLDDLGLHNDVYKNGKVAKYIFDNIC
What is the function of this protein?
Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.  Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H).  Required for elimination of toxic metabolites.
What are the official names of this protein?
Kynurenine formamidase, KFA, KFase, Arylformamidase, Biosynthesis of nicotinic acid protein 7, N-formylkynurenine formamidase, FKF.
What is the protein family that this protein belongs to?
Belongs to the kynurenine formamidase family.
Protein: MUTH_YERPS
Sequence: MSVYSLPPAPPSDEHQLFQRAQALSGFTLGELATRAQWVIPADLKRVKGWVGMLLEFYLGASAGSKPEQDFADIGIELKTIPISAQGKPLETTFVCVAPLTGNSGVTWENSHVRHKLARVLWVPVEGERHIPLAERRVGAPLLWSPNVEEEELLRRDWEELMDLIVLGKVESITARHGQVLQLRPKAANSRALTEAIGEFGQPIMTLPRGFYLKKTLTAPMLARHFLL
What is the function of this protein?
Sequence-specific endonuclease that cleaves unmethylated GATC sequences.  It is involved in DNA mismatch repair.
What are the official names of this protein?
DNA mismatch repair protein MutH, Methyl-directed mismatch repair protein.
What is the protein family that this protein belongs to?
Belongs to the MutH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_SHEB2
Sequence: MKIRIGHGFDVHKFGAARPLILCGVEVPYETGLVAHSDGDVVLHAISDAILGALALGDIGKHFPDTDAAYKGADSRVLLRHCYALARAKGFVLGNLDVTIIAQVPKMAPHIEAMRQILAADLTSELDDINVKATTTEHLGFTGRKEGIAVEAVVLMTRKHD
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: RS2_EXIS2
Sequence: MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQKTVKKVDEAYNFIREVASEGGNVLFVGTKKQAQDTVKEEAIRAGQYFINERWLGGTLTNFSTIKKRINRLKQLEKMEENGTFEVLPKKEVIILKKEMTRLEKFLGGIKDMPGVPDALFIVDPRKERIAIAEAHKLNIPIVAIVDTNCDPDEIDYVIPANDDAIRAVKLLTGKMADAILEVKQGEDNVAPETTEEVVADAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: COPA_DICDI
Sequence: MLYKFETKASRVKGLSFHPTRPWILASLHSGSIHLYDYRIKTLLEKFDEHEGPVRGINFHMTQPLFVSGGDDYKIKVWNYKQRRCLFTLKGHKDYIRSVEFHREAPWIVSSSDDMVIRIWNWQSRTCIAELNGHNHYVMSALFHPKDDLVVSASLDQTIRIWDISGLKKKMTTVKPYRENDPMRLQDELFGTDISVRLSLEGHDRGVNWASFHPTQPYIVSASDDHQVKLWRMNDPIVDTFRGHYNNVSCALFHPRQDLIISNSEDKTIRVWDIIKKSTVHMIRRDHDRFWTLASHPNQNLFAAGHDSGMIVFKLERERPLFVQNGDSGVFFLKKKNFNSFDFQAGRTVSLFHISKLPSNNGTQTMSYNQTERAILVSSDAEGGSYHLYKIPPKDSNTVNTKKGTGVAAIFVGRDRFAVLDKGNNVVIRDLENEEIKRCQIPFTIDWIYPSGSPGTILIQSEDKIHMFDIQQKKMLCEIQVHGVRYVIWSKDRNYVAFLTRDFIVLANKKLEQICMIHETVLPKSGVWDDNGVFIYSTSNHLKYLLQNGDNGTIRTLESTIYITGVKNNKVFAIDREFKNRIIEIDTTEYVLKLSLLQQNYNQVMTILRENRLVGKAIIAYLQKKGYPDVVHFVKDDRTRFNLALDAGNIDIALSSAKILDDKDCWNRLGVEALKQGNYQVVEMAYSRTSEFDRLSFLYLLVGNLSTLKKMISYESSDIMSRFHFSLYLGDVEERIKILQEAGLHQLAYITASIHGLTEKAESIGNLITSDGKSQLPQLPKQSYLLVPPSPINCNPNELNWPLLTTTKSVSDVMGENRFGVEQSTSTPTGDWESDEDIFSEGKSQQQSSQQQQQQQQKGDWEEDILIGDGNNGGGDDGGWERDDLKGLEKIGTDGFNNKQNDHVALFVPPQPGPSFSMIWARNSQFAVDHIAAGSFESAMNILNSQIGAVNFDPIKSMFMNIFMATRSSLGCNASTPSLLMPIQRKSAAPYITYGLGHLIERLKTNAYKSTTEGKFNDALSHFTYILHTIIFCSVDNKQEVNELKDLINICREYILGIKIELQRKELSIGAQKDSTLGRQAELAAYFTHCNLDPSHLILSLRSAMNCAYKVKHFNLAASFARRLISLNPNPDLATQAKKVFNFAQQTPTPSDIQQLNYDERNPFVICAHSYVPIYKGSPLIKCPYCSSCYLPTHKGKVCSVCQISEIGKDVQGLQVITIQK
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
What are the official names of this protein?
Coatomer subunit alpha, Alpha-coat protein, Alpha-COP.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NGDN_DANRE
Sequence: MAATAVGNDVIDRDLPTAVRLLNSLTEQIVSVTSHVRELIKKVREKAYQTSKGLSFLDLRYHLLLFYLQDITHLISLKTEGESLKDNSAIHRLVTIRTVLEKMRPLDQKLKYQIDKLVRTAVTGSLSENDPLHFRPNPQSLVSKLSESEDSDDDGVGGKTKEQKEPSGGRRYVPPRIAPMHYDGDLTEADRQKERVEKQKRAALRSSVIQELRQQYSDAPEEIRDRRDFQTDRQGREELNRKNYEESMMVRLSTTRDQKLRKRGMMGMTSQLSNITRFSDITALTGGEVQDIGNPKPKKKKIIKKGKKKVFRKRK
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.  Its dissociation from the complex determines the transition from state pre-A1 to state pre-A1* (By similarity).  May inhibit mRNA translation (By similarity).
What are the official names of this protein?
Neuroguidin, EIF4E-binding protein.
What is the protein family that this protein belongs to?
Belongs to the SAS10 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: MED22_YEAST
Sequence: MSNQALYEKLEQTRTILSVKLAELINMTTIADRNDDDEGSFAQENSELAVATTSVMMVNNQTMQLIKNVQDLLILTRSIKEKWLLNQIPVTEHSKVTRFDEKQIEELLDNCIETFVAEKTT
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.  The Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II.  The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 22, Mediator complex subunit 22, Suppressor of RNA polymerase B 6.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 22 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TATA_ACIBC
Sequence: MAGLSIWHVVIFAIVVILLFGTSKLKNIGKDVGGAVRDFKKSVREEDEAASLNSPRTIDAQVKTSESTSVKS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HIS6_BURM1
Sequence: MALAKRIIPCLDVTAGRVVKGVNFVELRDAGDPVEIARRYDEQGADELTFLDITATSDQRDLILPIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKVSMNSSAVANPQLVRDAADKYGSQCIVVAIDAKRVSADGEAPRWEVFTHGGRKGTGLDAIEWARKMAEFGAGEILLTSMDRDGTKSGFDLALTRGVSDAVPVPVIASGGVGSLQDLADGIKDGRADAVLAASIFHYGEHTVGEAKRFMAEQGIPVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO2_PROM4
Sequence: MTQEKKDFTIHALPVLKDNIIWIWEASGQAVVVDPAVSEPVKEFLSQNNLALNSVLQTHHHDDHIGGTRDLISNWPSASIIACKTDLERIPFQTHSVTDQEVFTLFGYSVKVLEVPGHTRGHVAYYLSDTNADNRNPALFCGDTLFAGGCGRLFEGTPHEMFKSLKLLNSLPSNTKIYCAHEYTESNLHWANHLYPEDLLIKKRLEYVSSQRANGLLSLPSTIAEERKTNLFFRARTLEQFSQFRKHKDNWMS
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: UVRC_LISMH
Sequence: MSSEHIQNKLALLPDQPGCYLMKDRQGTIIYVGKAKILKNRVRSYFSGTHDSKTQRLVQEIVDFEYIVTSSNVEALLLEINLIKKHDPRFNIRLKDDKTYPFIKITNERHPRLIITRQVKKDKGKYFGPYPNVYAANEVKRILDRLYPLRKCSTLPNKVCLYYHLGQCLAPCVFDVEASKYKEMQDEIVAFLNGGYKTVKNDLMKKMQEAAENMEFEKAGEFRDQINAIETTMEKQKMTMNDFVDRDVFGYAIDKGWMCVQVFFIRQGKLIERDVSQFPFYNDADEDFLTFIGQFYQKANHIPPKEIYLPDDVDSEAVQAVVPDTKIIVPQRGNKKDLVKLAYKNAKISLNEKFMLLERNEERTVGAVERLGEAMGIPTPSRVEAFDNSNIHGTDPVSAMVTFLDGKPSKNDYRKYKIKTVEGPDDYATMREVIRRRYWRVLKEGLPMPDLILIDGGKGQIDSAKDVLTNELGLDIPVAGLAKDDKHRTSQLLFGDPLEIVPLERNSQEFYLLQRMQDEVHRFAITFHRQLRSKTGFQSILDGIPGVGPGRKKKLLKHFGSMKKLKEASVEEIKEAGVPLNVAEEVHKHITAFNEKAKNTEQK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LTMC_EPIFI
Sequence: MTSGAWLVARPAAIEIAALLFAFTLGYLVKYTINYQSVVSQAIDHYGYGYERTSHEGIGGSNGKIPDCPYSYVISLYGHNHFSPLVDFLHPTLKHKYPKKHSLILDIMDAVHLCLIMVDDICDHSPKRKNHTTAHLLYGSCETANRAYFVLTKVINRAMKEQPVLGIELLRALELILEGQDMSLVWRRDGLRSFESYGEESLLTYKNMALLKTGTLFVLLGRLLNQGGHQSDDLLGRFGWYAQLQNDCKNIYSEEYAFNKGTVAEDLRNRELSFPVVVALNDKHTEPQIRKAFQSQNQGDIKRALQALESPSVKNTCLKTLQEAGQGLENLVAVWGRKEQMHFTK
What is the function of this protein?
Prenyltransferase; part of the gene cluster that mediates the biosynthesis of lolitrems, indole-diterpene mycotoxins that are potent tremorgens in mammals, and are synthesized by clavicipitaceous fungal endophytes in association with their grass hosts (PubMed:16765617).  The geranylgeranyl diphosphate (GGPP) synthase ltmG is proposed to catalyze the first step in lolitrem biosynthesis (PubMed:16765617, PubMed:15991026).  LtmG catalyzes a series of iterative condensations of isopentenyl diphosphate (IPP) with dimethylallyl diphosphate (DMAPP), geranyl diphosphate (GPP), and farnesyl diphosphate (FPP), to form GGPP (PubMed:16765617, PubMed:15991026).  GGPP then condenses with indole-3-glycerol phosphate to form 3-geranylgeranylindole, an acyclic intermediate, to be incorporated into paxilline (PubMed:16765617).  Either ltmG or ltmC could be responsible for this step, as both are putative prenyl transferases (PubMed:16765617).  The FAD-dependent monooxygenase ltmM then catalyzes the epoxidation of the two terminal alkenes of the geranylgeranyl moiety, which is subsequently cyclized by ltmB, to paspaline (PubMed:16765617, PubMed:15991026).  The cytochrome P450 monooxygenases ltmQ and ltmP can sequentially oxidize paspaline to terpendole E and terpendole F (PubMed:22750140).  Alternatively, ltmP converts paspaline to an intermediate which is oxidized by ltmQ to terpendole F (PubMed:22750140).  LtmF, ltmK, ltmE and ltmJ appear to be unique to the epichloe endophytes (PubMed:16765617, PubMed:15991026).  The prenyltransferase ltmF is involved in the 27-hydroxyl-O-prenylation (PubMed:22750140).  The cytochrome P450 monooxygenase ltmK is required for the oxidative acetal ring formation (PubMed:22750140).  The multi-functional prenyltransferase ltmE is required for C20- and C21-prenylations of the indole ring of paspalanes and acts together with the cytochrome P450 monooxygenase ltmJ to yield lolitremanes by multiple oxidations and ring closures (PubMed:22750140).  The stereoisomer pairs of lolitriol and lolitrem N or lolitrem B and lolitrem F may be attributed to variations in the way in which ring closure can occur under the action of ltmJ (PubMed:22750140).  While the major product of this pathway is lolitrem B, the prenyl transferases and cytochrome P450 monooxygenases identified in this pathway have a remarkable versatility in their regio- and stereo-specificities to generate a diverse range of metabolites that are products of a metabolic grid rather than a linear pathway (PubMed:22750140).
What are the official names of this protein?
Prenyltransferase ltmC, Lolitrem B biosynthesis cluster 2 protein C.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
Protein: PCDA4_HUMAN
Sequence: MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQLQTTEESFAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
What is the function of this protein?
Calcium-dependent cell-adhesion protein involved in cells self-recognition and non-self discrimination.  Thereby, it is involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin alpha-4, PCDH-alpha-4.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Detected in dendrites and synapses.
Protein: PANC_HELHP
Sequence: MRVIQSICEMRHYRAGIANDKTIGFVATMGALHQGHLSLMKASLAENDYTIVSIFVNPTQFGANEDFGAYPRTLEADIALCERVGVSAIFAPSIDDMYEDDEVGFSAPKKMGYILEGFDRPTHFAGVLQIVLKLFCLIKPHRAYFGQKDAQQVLILQKMVRDLFLDIHIVPCPIQRDSDGLALSSRNIYLSASERQKALCIPRTIELVKKRILQGEREVATLREIALQSLQSEDITLFYAQFCNHKLEPITHIVENKSIFLIAAKVGQTRLLDNLWI
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AK1A1_CRIGR
Sequence: MASCVLLHTGQKMPLIGLGTWKSNPGQVKAAIKYALSVGYRHIDCAAVYGNEIEIGEALKENVGPGKAVPREELFVTSKLWNTKHHPEDVEAALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNDDGTIRYDSTHYKETWKALEALVAKGLVKALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHGRSPAQILLRWQVQRKVVCIPKSITPSRILQNIQVFDFTFSPEEMKQLDALNKHWRYIVPMITVDGKSVPRDAGHPLYPFNDPY
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols.  Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosaccharides and bile acids, with a preference for negatively charged substrates, such as glucuronate and succinic semialdehyde (By similarity).  Plays an important role by catalyzing the reduction of D-glucuronic acid and D-glucurono-gamma-lactone.  Functions as a detoxifiying enzyme by reducing a range of toxic aldehydes.  Reduces methylglyoxal and 3-deoxyglucosone, which are present at elevated levels under hyperglycemic conditions and are cytotoxic.  Involved also in the detoxification of lipid-derived aldehydes like acrolein (By similarity).  Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs (By similarity).  Displays no reductase activity towards retinoids (By similarity).
What are the official names of this protein?
Aldo-keto reductase family 1 member A1, Alcohol dehydrogenase [NADP(+)], Aldehyde reductase, Glucuronate reductase, Glucuronolactone reductase.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Apical cell membrane.
Protein: SUS2_SOLTU
Sequence: MAERVLTRVHSLRERLDATLAAHRNEILLFLSRIESHGKGILKPHQLLAEFESIHKEDKDKLNDHAFEEVLKSTQEAIVLPPWVALAIRLRPGVWEYVRVNVNALIVEELTVPEFLQFKEELVNGTSNDNFVLELDFEPFTASFPKPTLTKSIGNGVEFLNRHLSAKMFHDKESMTPLLEFLRVHHYKGKTMMLNDRIQNLYTLQKVLRKAEEYLTTLSPETSYSAFEHKFQEIGLERGWGDTAERVLEMICMLLDLLEAPDSCTLEKFLGRIPMVFNVVILSPHGYFAQENVLGYPDTGGQVVYILDQVPALEREMLKRIKEQGLDIKPRILIVTRLLPDAVGTTCGQRLEKVFGTEHSHILRVPFRTEKGIVRKWISRFEVWPYMETFIEDVGKEITAELQAKPDLIIGNYSEGNLAASLLAHKLGVTQCTIAHALEKTKYPDSDIYLNKFDEKYHFSAQFTADLIAMNHTDFIITSTFQEIAGSKDTVGQYESHMAFTMPGLYRVVHGIDVFDPKFNIVSPGADVNLYFPYSEKEKRLTTFHPEIEDLLFSDVENEEHLCVLKDRNKPIIFTMARLDRVKNLTGLVEWYAKNPRLRELVNLVVVGGDRRKESKDLEEQAEMKKMYELIKTHNLNGQFRWISSQMNRVRNGELYRYIADTRGAFVQPAFYEAFGLTVVEAMSCGLPTFATNQGGPAEIIVHGKSGFQIDPYHGEQAADLLADFFEKCKVDPSHWEAISEGGLKRIQEKYTWQIYSDRLLTLAAVYGFWKHVSKLDRLEIRRYLEMFYALKFRKLAQLVPLAVE
What is the function of this protein?
Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways.
What are the official names of this protein?
Sucrose synthase, SS65, Sucrose-UDP glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Plant sucrose synthase subfamily.
Protein: ZEP_ORYSJ
Sequence: MALLSATAPAKTRFSLFSHEEAQHPHPHALSACCGGGASGKRQRARARVAAAMRPADAAASVAQAASPGGGGEGTRRPRVLVAGGGIGGLVLALAARRKGYEVTVFERDMSAVRGEGQYRGPIQIQSNALAALEAIDMSVAEEVMREGCVTGDRINGLVDGISGSWYIKFDTFTPAAERGLPVTRVISRMTLQQILARAVGDDAILNDSHVVDFIDDGNKVTAILEDGRKFEGDLLVGADGIWSKVRKVLFGQSEATYSEYTCYTGIADFVPPDIDTVGYRVFLGHKQYFVSSDVGAGKMQWYAFHKEPAGGTDPENGKNKRLLEIFNGWCDNVVDLINATDEEAILRRDIYDRPPTFNWGKGRVTLLGDSVHAMQPNLGQGGCMAIEDGYQLAVELEKSWQESAKSGTPMDIVSSLRRYEKERILRVSVIHGLARMAAIMATTYRPYLGVGLGPLSFLTKLRIPHPGRVGGRFFIKYGMPLMLSWVLGGNSTKLEGRPLSCRLSDKANDQLRRWFEDDDALEQAMGGEWYLLPTSSGDSQPIRLIRDEKKSLSIGSRSDPSNSTASLALPLPQISENHATITCKNKAFYVTDNGSEHGTWITDNEGRRYRVPPNFPVRFHPSDAIEFGSDKKAVFRVKVLSTLPYESARGGPQILQAA
What is the function of this protein?
Zeaxanthin epoxidase that plays an important role in the xanthophyll cycle and abscisic acid (ABA) biosynthesis.  Converts zeaxanthin into antheraxanthin and subsequently violaxanthin.  Required for resistance to osmotic and drought stresses, seed development and dormancy.
What are the official names of this protein?
Zeaxanthin epoxidase, chloroplastic, OsZEP1, Protein ABA DEFICIENT 1, OsABA1.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Peripheral membrane protein. Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.