PharMolix/UniProtQA huggingface dataset:
Protein: MAP7_MOUSE
Sequence: MAEQGAGGDGHRGGDGATHSDPASDGYKVQEKRTAPSRPTSTVSGQTSNHSGNKPDPPPVLRVDDRQRLARERREEREKQLAARETVWLEREERARQHYERHLEARKKKLEDQRLKEERRRAAVEEKRRQRLEEDKERHEAVVRRTMERSQKPRQKSNRWSWGSPLHGSSSIHSGDPDRRSVSTMNLSKHVDPVISKRLSSSSATLLNSPDRARRLQLSPWESSVVSRLLTPTHSFLARSKSTAALSGDTASCSPIIMPFKAAHSRNPVDRPKLFVTPPEGSARRRTIHGLASHKREREREHVPFHVSPGARRTLSPSNLKARSPAPARLWLPSKSMPHLPGTPRPASSLPPGSVRAASAQAPSSSPGNIRPFKREVKVEPEKKDPLPAVKSRVPLVKVEEVTVEEGTPVKPPEPAAPASAPIATPAPAPATDPAPVPAPSSTVTVGVVPKTSAGTTDPEEATRLLAEKRRLAREQREKEERERKEKEELERQKIEELARRVAEERSRREEEARRLEEEQAREKEELALRLAEEERERWEREEVERVQKQKEEEARAREEAERARQEREKHFQKEEQERLERKKRLEEIMRRTRRTETADKKTTEQRNGDIAKGVLTGEPEVPALPCMASSGNGESAESPHGVALQQSEVTTESSPDLEKQPNENGMSIQNENFEEVINLPVGSKASRLDVTNENPEIPLKPILAFNDEGTLGPLPQVDGVQTQQTAEVI
What is the function of this protein?
Microtubule-stabilizing protein that may play an important role during reorganization of microtubules during polarization and differentiation of epithelial cells.  Associates with microtubules in a dynamic manner.  May play a role in the formation of intercellular contacts.  Colocalization with TRPV4 results in the redistribution of TRPV4 toward the membrane and may link cytoskeletal microfilaments.
What are the official names of this protein?
Ensconsin, Epithelial microtubule-associated protein of 115 kDa, E-MAP-115, Microtubule-associated protein 7, MAP-7.
What is the protein family that this protein belongs to?
Belongs to the MAP7 family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Basolateral cell membrane. Cytoplasm, cytoskeleton. Note=Colocalized on microtubules. An intracellular redistribution is triggered during induction of keratinocyte terminal differentiation from microtubules with a perinuclear localization to cortical microtubules organized in spike- like bundles facing intercellular contacts.
Protein: DADA_ECOLI
Sequence: MRVVILGSGVVGVASAWYLNQAGHEVTVIDREPGAALETSAANAGQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLDGTQFQLKWMWQMLRNCDTSHYMENKGRMVRLAEYSRDCLKALRAETNIQYEGRQGGTLQLFRTEQQYENATRDIAVLEDAGVPYQLLESSRLAEVEPALAEVAHKLTGGLQLPNDETGDCQLFTQNLARMAEQAGVKFRFNTPVDQLLCDGEQIYGVKCGDEVIKADAYVMAFGSYSTAMLKGIVDIPVYPLKGYSLTIPIAQEDGAPVSTILDETYKIAITRFDNRIRVGGMAEIVGFNTELLQPRRETLEMVVRDLYPRGGHVEQATFWTGLRPMTPDGTPVVGRTRFKNLWLNTGHGTLGWTMACGSGQLLSDLLSGRTPAIPYEDLSVARYSRGFTPSRPGHLHGAHS
What is the function of this protein?
Catalyzes the oxidative deamination of D-amino acids.  Has broad substrate specificity; is mostly active on D-alanine, and to a lesser extent, on several other D-amino acids such as D-methionine, D-serine and D-proline, but not on L-alanine.  Participates in the utilization of L-alanine and D-alanine as the sole source of carbon, nitrogen and energy for growth.  Is also able to oxidize D-amino acid analogs such as 3,4-dehydro-D-proline, D-2-aminobutyrate, D-norvaline, D-norleucine, cis-4-hydroxy-D-proline, and DL-ethionine.
What are the official names of this protein?
D-amino acid dehydrogenase, D-alanine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ARGC_THISH
Sequence: MIRAGIVGATGYTGVELLRLLLAHPGAEPAVVTSRGNAGERLDAMFPNLRGHTDLAFTEPDPGLLAECDVVFFATPHGVAHAMAGELLSRGTRVIDLSADFRIRDAALWSRWYGQPHGAPELLDQAVYGLPEINRKRIPDARLIAVPGCYPTAVSLGFIPLLEAGLVDTAHLVADAKSGVSGAGRKAQVGMLLCEASENFKAYGVAGHRHLPEILQTLGDVAGQTPGLTFVPHLLPMIRGIEASLYAVLKDMDTDLQALYEQRYAAEPFVDVMPPGSHPETRSVRGTNRCRIAVHRPQGGDTAVVLSVIDNLVKGASGQAVQNMNLMFGLPETAGLDGIAVLP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1894_SYNY3
Sequence: MATINIGIPEADRIKIAESLKKLLADTYTLYLQTHNFHWNVTGPQFRDLHLMFEEQYNELALAVDDIAERIRSLDVFAPGTYKEFAKLSSVQEVDGIPTSKEMVDILTKGHETIVQSCRDVLKCSQPADDESTIALASDRMRVHEKTAWMLRAMNK
What are the official names of this protein?
Protein slr1894.
What is the protein family that this protein belongs to?
Belongs to the Dps family.
Protein: HCP_SALPK
Sequence: MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKAREYGIINHDVDNFAPRAFFSTLTNVNFDSPRIVGYAREAIAMREALKAQCLSVDANAHCDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECAMEIGQMNFKVMSILDAGETTKYGHPTPTQVNVKATEGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGSYDDRIWTRSIVGWPGVSHLEGDDFGPVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIFLVGGCDGARGERNYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFFTPDLLAILNEKFGLRSVTTVEEDMKQLLSA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUCC_CERS4
Sequence: MSRIAEHLVRIGPRFLPFADAASDQLPLRKLLRLSLFQVAVGMAIVLLVGTLNRVMIVELKVPASVVGIMISLPLLFAPFRALIGFKSDTHVSALGWRRVPWIYRGTLALWGGFAIMPFALIVLGGQGYAEGQPFWLGVSSAALAFLMVGGGVHTIQTVGLALATDLAPREDQPKVVGLMYVVLLISMIFASIGFGWLLDPYYDAQLIKVISGVAVAVFFLNMIALWKMEPRNRAFTVKPEKEPEFGDHWREFISRENALHGLIVIGLGTLGFGMADVILEPYGGEVLSMTVAETTRLTATFAGGGLVGFWLASWVLGRGFDPLRMAFLGAAAGLPGFFAIMGATEMTNVWVFLLGTLVVGFGGGLFSHGTLTATMRLAPKEQVGLALGAWGAVQATAAGVAIAGAGVLRDILQAMPDLSGYGPGAPYVAVFALEAGFLFLTMIVILPLLRSALAARRL
What is the function of this protein?
PucC is required for high-level transcription of the puc operon.
What are the official names of this protein?
Protein PucC.
What is the protein family that this protein belongs to?
Belongs to the PucC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GATC_RHILO
Sequence: MSVDLQTVKRVARLARIAVSEEDAERMTGELNAILGFVEQLNEVDVSGVEPMTSVTPMEMKKRQDVVTDGNKAADIVANAPATEENFFLVPKVVE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C, Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: PXPA_VIBC1
Sequence: MTLNNQQLTLNCDMGESFGAWKMGADECVMPFVDMANIACGFHASDPNVMHDTITLANQHDVEIGAHPGYPDLQGFGRRSIKMTNDEITNMVIYQVGALQALCKAQYTDIGYIKPHGALYNDMMQSDGVFLAVVKAVALFKVPLMILASKENEKYLEIADDFDVPLLFEAFADRLYQDDGMLTPRTQPNAVLNSEHAILEQVRMLAESGRVKTASGQYILLEADTICVHGDNNESIALVQKIRQSLYTGGN
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: SNF8_YEAST
Sequence: MKQFGLAAFDELKDGKYNDVNKTILEKQSVELRDQLMVFQERLVEFAKKHNSELQASPEFRSKFMHMCSSIGIDPLSLFDRDKHLFTVNDFYYEVCLKVIEICRQTKDMNGGVISFQELEKVHFRKLNVGLDDLEKSIDMLKSLECFEIFQIRGKKFLRSVPNELTSDQTKILEICSILGYSSISLLKANLGWEAVRSKSALDEMVANGLLWIDYQGGAEALYWDPSWITRQL
What is the function of this protein?
Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.  The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation.  The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex.
What are the official names of this protein?
Vacuolar-sorting protein SNF8, ESCRT-II complex subunit VPS22, Vacuolar protein-sorting-associated protein 22.
What is the protein family that this protein belongs to?
Belongs to the SNF8 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein.
Protein: PYRC_YERPE
Sequence: MTAQPQTLKIRRPDDWHIHLRDDEMLSTVLPYTSEVFARAIVMPNLAQPITTVASAIAYRERILAAVPAGHKFTPLMTCYLTNSLDAKELTTGFEQGVFTAAKLYPANATTNSTHGVSDIPAIYPLFEQMQKIGMPLLIHGEVTDAAVDIFDREARFIDQILEPIRQKFPELKIVFEHITTKDAADYVLAGNRFLGATVTPQHLMFNRNHMLVGGIRPHLFCLPILKRSTHQQALRAAVASGSDRFFLGTDSAPHAKHRKESSCGCAGVFNAPAALPAYASVFEELNALQHLEAFCALNGPRFYGLPVNDDVVELVRTPFLQPEEIPLGNESVIPFLAGQTLNWSVKR
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: VU51_HHV6Z
Sequence: MEKETKSLAWPATAEFYGWVFIFSSIQLCTVVFLTVRFNGFKVGREYAVFTFAGMSFNCFLLPIKMGLLSGHWTLPRDFCAILLYIDDFSAYFSSWSLVFMAIERINYFCYSTPLLNENSKALAKVCFPIVWVVSGVQALQMLNNYKATALQNETGQCFLAFLRSGHDMWLMLVYSVVIPVMLVFFYLYSKNFMLLKDELSSVTTYLCIYLLLGTIAHLPKAALSEIESDKIFYGLRDIFMALPVLKVYYISAMAYCMACDDHTVPVRLCSIWLVNLCKKCFSCTRREKGSDLEVGIKMLK
What are the official names of this protein?
G-protein coupled receptor homolog U51.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Host cell membrane; Multi-pass membrane protein.
Protein: INSG_ECOLI
Sequence: MHIGQALDLVSRYDSLRNPLTSLGDYLDPELISRCLAESGTVTLRKRRLPLEMMVWCIVGMALERKEPLHQIVNRLDIMLPGNRPFVAPSAVIQARQRLGSEAVRRVFTKTAQLWHNATPHPHWCGLTLLAIDGVFWRTPDTPENDAAFPRQTHAGNPALYPQVKMVCQMELTSHLLTAAAFGTMKNSENELAEQLIEQTGDNTLTLMDKGYYSLGLLNAWSLAGEHRHWMIPLRKGAQYEEIRKLGKGDHLVKLKTSPQARKKWPGLGNEVTARLLTVTRKGKVCHLLTSMTDAMRFPGGEMGDLYSHRWEIELGYREIKQTMQRSRLTLRSKKPELVEQELWGVLLAYNLVRYQMIKMAEHLKGYWPNQLSFSESCGMVMRMLMTLQGASPGRIPELMRDLASMGQLVKLPTRRERAFPRVVKERPWKYPTAPKKSQSVA
What is the function of this protein?
Involved in the transposition of the insertion sequence IS4.
What are the official names of this protein?
Transposase InsG for insertion sequence element IS4.
What is the protein family that this protein belongs to?
Belongs to the transposase 11 family.
Protein: AHPD_ANADE
Sequence: MAALDAIREALPEPARDIKLNLQAVLQPGPLTPAQRWGVAVATAAAARNERLLAAILADARAEVEPAVVEDALAAAAVMAMNNVYYRFRHMVGKPSYSEKPARLRMNRLVKPAASKLDFELFALAVSAVNGCETCVRSHEQVVVGGGVSEDQVHDAVRIAAVVHAAAVALELAGHAAAPSAAAAAG
What is the function of this protein?
Antioxidant protein with alkyl hydroperoxidase activity.  Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
What are the official names of this protein?
Alkyl hydroperoxide reductase AhpD, Alkylhydroperoxidase AhpD.
What is the protein family that this protein belongs to?
Belongs to the AhpD family.
Protein: RS7_ANOGA
Sequence: MVFGSKVIKAGNGEPDAFETQIGQAILELEMNSDLKPQLRDLYITRAREVEFNNKKAIIIYVPVPKQKAFQKVQTRLVRELEKKFSGKHVVFIAERRILPKPMRGRRDPNKQKRPRSRTLTAVYDAILEDLVFPAEVVGKRIRVKLDGSQLIKVHLDKNQQTTIEHKVDTFASVYKKLTGRDVTFEFPENYL
What are the official names of this protein?
40S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS7 family.
Protein: GLSA2_ECOLI
Sequence: MAVAMDNAILENILRQVRPLIGQGKVADYIPALATVDGSRLGIAICTVDGQLFQAGDAQERFSIQSISKVLSLVVAMRHYSEEEIWQRVGKDPSGSPFNSLVQLEMEQGIPRNPFINAGALVVCDMLQGRLSAPRQRMLEVVRGLSGVSDISYDTVVARSEFEHSARNAAIAWLMKSFGNFHHDVTTVLQNYFHYCALKMSCVELARTFVFLANQGKAIHIDEPVVTPMQARQINALMATSGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPHEMAIAVWSPELDDAGNSLAGIAVLEQLTKQLGRSVY
What are the official names of this protein?
Glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: NODZ_AZOC5
Sequence: MYNSACPEGRSVISRRRTGLGDCLWSLAAAWSYARHTRRSLVVDWSESCYSADPNINLFPVLFDNINDIGGVSVHYVSRTSSLALESSVIPAWWRLPVKQRGTRSDAQIFRERDELRNLFFSRRDADAAAVICDCCLMWCCDEDLEREFYDHLIVNQYVRQEVDRVYAERFLGNVVIGVHIRHGNGEDILDHDRYWCEENAAMNLVAHKIREERRKFPFRSTKIFLCTDSPAVSEWFRREMPGLFATEKEFRQRGEGELHSAHFGLGGAVAALVDMQLLSRCDVLIRYPPTSAFSRWPSLLVERVFDFDLARGVFCQADRKAGGASSG
What is the function of this protein?
Fucosyltransferase which adds the fucose moiety of the nod factor on its terminal reducing N-acetylglucosamine end.  Uses GDP-fucose as the donor group.
What are the official names of this protein?
Nodulation protein Z.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 23 family.
Protein: PENKB_XENLA
Sequence: ACTLECEGKLPSAKAWGTCKELLQLTKLDGVQDGEKYQDNNDSHYIAKKYGGFMKRYGGFMKKMDELYHAEPEEDDAGGEILAKNYGGFMKKEYDSNRDASDLLRELLATSGDPESAIYHDNNSETPGEMNKRYGGFMRGYRRSTDLEDETRGIQKRYGGFMRRVGRPEWWQDYQKRYGGFMTRFTDSFLPSDEDGESYSKENPDMEKRYGGFMRF
What is the function of this protein?
Enkephalin neuropeptides compete with and mimic the effects of opiate drugs.  They play a role in a number of physiologic functions, including pain perception and responses to stress.
What are the official names of this protein?
Proenkephalin-A-B.
What is the protein family that this protein belongs to?
Belongs to the opioid neuropeptide precursor family.
What are the subcellular locations of this protein?
Secreted.
Protein: KPRS_DESPS
Sequence: MPNIIKIFSGNAHPQLADEIAAHLGMQVSEADVRKFSDGEIFVEIKKNVRGTDAFIVQPTCTPVNDNLMELVLMVDALRRASARRITAVVPYYGYARQDRKSAPRVPISAKVVAEMFMAVGVRRVLCMDLHAGQIQGFFNIPVDHLYAAPVLLKHIKKEFGEDVVMVSPDAGGVERTRAFAKRLNTGLAIIDKRRDRPNECEAMHVIGDVRGKVAILMDDMADTAGTICNGAKTLLENGAKEVHACCTHPVLSGPAVERITNSDLKSFVVTNTIPLGEEAKNCPKIKQLSVSALLADAIERIHNEDSVSSLFV
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_GLUOX
Sequence: MTDTPLSLIRNFSIIAHIDHGKSTLADRLIQACGALTAREMKNQVLDSMELEQERGITIKAQTVRLTYPAKDGKVYTLNLMDTPGHVDFAYEVSRSLAACEGSLLVVDASQGVEAQTLANVYQALDANHEIVPVLNKIDLPAAEPERVRAQIEDVVGIPADDAVEISAKTGINIEGVLEALVQRLPAPTGDAEAPLQALLVDSWYDAYLGVIILVRIKDGRLKRGDRIRMMQTGATYHVDQVGVFLPKMQSVESLGPGEMGYINAAIKTVADCNVGDTVTLDKRPAEKALPGFKPSIPVVWCGLFPIDADDFEKLRDSLGKLRLNDASFHFEAETSAALGFGFRCGFLGLLHLEIIQERLSREFNLDLIATAPSVVYKMHMTDGTVEELHNPADMPELSKIEMIEEPWIKATIMVQDEYLGPVLTLCSERRGIQVDLTYVGNRAMAVYRLPLNEVVFDFYDRLKSISRGYASFDYQMDGYEESDLVRISILVNHEPVDALSFISHRTVAEQRGRSICAKLKDLIPKQLFKIAIQAAIGSKVIARETIGALSKDVTAKCYGGDISRKRKLLDKQKEGKKRMRQFGKVEIPQSAFLAALKMD
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GLGS_ARATH
Sequence: MASVSAIGVLKVPPASTSNSTGKATEAVPTRTLSFSSSVTSSDDKISLKSTVSRLCKSVVRRNPIIVSPKAVSDSQNSQTCLDPDASSSVLGIILGGGAGTRLYPLTKKRAKPAVPLGANYRLIDIPVSNCLNSNISKIYVLTQFNSASLNRHLSRAYASNMGGYKNEGFVEVLAAQQSPENPNWFQGTADAVRQYLWLFEEHNVLEYLILAGDHLYRMDYEKFIQAHRETDADITVAALPMDEQRATAFGLMKIDEEGRIIEFAEKPKGEHLKAMKVDTTILGLDDQRAKEMPFIASMGIYVVSRDVMLDLLRNQFPGANDFGSEVIPGATSLGLRVQAYLYDGYWEDIGTIEAFYNANLGITKKPVPDFSFYDRSAPIYTQPRYLPPSKMLDADVTDSVIGEGCVIKNCKIHHSVVGLRSCISEGAIIEDSLLMGADYYETATEKSLLSAKGSVPIGIGKNSHIKRAIIDKNARIGDNVKIINSDNVQEAARETDGYFIKSGIVTVIKDALIPTGTVI
What is the function of this protein?
This protein plays a role in synthesis of starch.  It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase small subunit, chloroplastic, ADP-glucose pyrophosphorylase, ADP-glucose synthase, AGPase B, Alpha-D-glucose-1-phosphate adenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LPXD_YEREN
Sequence: MPSIRLADLAQQLDAQVHGDGDLVITGIASMHSAEPSQITFLSNSRYQEQLATCNAGAVVLTEADLPFCKSAALVVKNPYLTYARMAQIMDTTPQPAQNIAPGAVISPQATLGENVSIGANAVIESGVVLGDNVVIGAGCFIGKNTHIGAGSRLWANVSVYHEVVIGQNCLIQSGTVIGADGFGYANDRGNWIKIPQLGSVHIGDRVEIGACTTIDRGALDNTIIGNGVIIDNQCQIAHNVVIGDNTAVAGGVIMAGSLKVGRYCMIGGASVINGHMEICDKVTITGMGMVMRPITEPGLYPSGIPLQPNKVWRKTAALVMNIDGINKRLKAIERKIDKE
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase, UDP-3-O-(3-OHC14)-GlcN N-acyltransferase, UDP-3-O-(3-hydroxytetradecanoyl)glucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: FBRL_HUMAN
Sequence: MKPGFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSGKNVMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGEKRVSISEGDDKIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYRPPPKVKN
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins (PubMed:24352239, PubMed:30540930, PubMed:32017898).  Involved in pre-rRNA processing by catalyzing the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA (PubMed:30540930).  Site specificity is provided by a guide RNA that base pairs with the substrate (By similarity).  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA (By similarity).  Probably catalyzes 2'-O-methylation of U6 snRNAs in box C/D RNP complexes (PubMed:32017898).  U6 snRNA 2'-O-methylation is required for mRNA splicing fidelity (PubMed:32017898).  Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ104me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (PubMed:24352239, PubMed:30540930).  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).
What are the official names of this protein?
rRNA 2'-O-methyltransferase fibrillarin, 34 kDa nucleolar scleroderma antigen, Histone-glutamine methyltransferase, U6 snRNA 2'-O-methyltransferase fibrillarin.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Note=Fibrillar region of the nucleolus.
Protein: CRK46_ARATH
Sequence: MASTLISSLAVVLPLTLLAPSMSMKISRIDVLGYICNNGTVSNEEAYRRSYQINLDAIRGDMRHVKFGTHEHGDPPERMYVLSQCVSDLSSDECSLCWSRATDLLSQCFPATGGWFHLDGCFVRADNYSFYQEPVSHQDTKICASDKEKSAEFKGLVKEVTKSIVEAAPYSRGFSVAKMGIRDLTVYGLGVCWRTLNDELCKLCLADGALSVTSCLPSKEGFALNAGCYLRYSNYTFYNERGLLAMSFTKENLTYIFVISMVGVLAIAAGFWCGKCFYMRTSPKKKIKGTKTKKFHLFGHLRIEKESESICTESHLMSFEYSTLKKATNNFNESCKLGVGGYGEVFKGTLSDGREIAIKRLHVSGKKPRDEIHNEIDVISRCQHKNLVRLLGCCFTNMNSFIVYEFLANTSLDHILFNPEKKKELDWKKRRTIILGTAEGLEYLHETCKIIHRDIKASNILLDLKYKPKISDFGLAKFYPEGGKDIPASSLSPSSIAGTLGYMAPEYISKGRLSNKIDAYSFGVLVLEITSGFRNNKFRSDNSLETLVTQVWKCFASNKMEEMIDKDMGEDTDKQEMKRVMQIGLLCTQESPQLRPTMSKVIQMVSSTDIVLPTPTKPPFLHDSM
What are the official names of this protein?
Cysteine-rich receptor-like protein kinase 46, Cysteine-rich RLK46.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CRK subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YACG_ENT38
Sequence: MSEVINVNCPTCGKAVVWGEISPFRPFCCKRCQLIDLGEWAAEEKRIPSEGGLSDSDDWSEELK
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: ISCR_SALTI
Sequence: MRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQLFSRLRKNGLVSSVRGPGGGYLLGKDAGSIAVGEVISAVDESVDATRCQGKGGCQGGDKCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSGRQHTHDAPRASGRAQDAIDVKLRA
What is the function of this protein?
Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
What are the official names of this protein?
HTH-type transcriptional regulator IscR.
Protein: LEXA_BURA4
Sequence: MTKLTARQQQVFDLIRRAIERSGFPPTRAEIAAELGFSSPNAAEEHLRALARKGVIELAAGASRGIRLLGIDDAPHQFTLPHAGLMQLSLPLVGRVAAGSPILAQEHISQHYACDPALFTSKPDYLLKVRGLSMRDAGILDGDLLAVQKRTEAKDGQIIVARLGDDVTVKRLMRRPGGLELIAENPDYENIFVKAGSAEFALEGIAVGLIRSGEL
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RL15E_METBU
Sequence: MSKSFYGYIRDAWKNPDETYVRDLRWERLQVWRKEGSVTRVERPTRIDRARSLGYKAKQGIVVARVKVRRGSMRKSRYIRGRRTQHTGKNKITVGKSIQRISEERAARKYPNMEVLNSYWVGEDGKQKWYEVILVDPSHPVIKSDKNLNWICGKAHSGRVFRGKTSAGRKGRGMQTRGTGTEKTRPSVRSNLNRSKK
What are the official names of this protein?
50S ribosomal protein L15e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.