PharMolix/UniProtQA huggingface dataset:
Protein: PUR2_BACSU
Sequence: MNVLIIGKGGREHTLAWKAAQSSLVENVFAAPGNDGMAASAQLVNIEESDHAGLVSFAKQNQVGLTIVGPEVPLIEGLVDEFEKAGLHVFGPSKAAAIIEGSKQFAKDLMKKYDIPTAEYETFTSFDEAKAYVQEKGAPIVIKADGLAAGKGVTVAMTEEEAIACLHDFLEDEKFGDASASVVIEEYLSGEEFSLMAFVKGEKVYPMVIAQDHKRAFDGDKGPNTGGMGAYSPVPQISEETVRHAVETIVKPAAKAMVQEGRSFTGVLYAGLMLTENGSKVIEFNARFGDPETQVVLPRMESDLVQVLLDLLDDKEVDLRWKDTAAVSVVLASEGYPESYAKGTPIGSLAAETEQVVVFHAGTKAEGGEFVTNGGRVANVTAFDETFEAARDRVYKAVDEIFKPGLFFRKDIGARALKAAQK
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: SUCC_AZOSB
Sequence: MKIHEYQAKEVLRKYGVVTPRGIPCFSVDEAVKAAEELGGKIWVVKAQIHAGGRGKGGGVKLGKSLDEVRTLAGQILGMQLVTHQTGPEGQKVRRLLIEEGADIKKEYYVAALTDRATQKVAMMASSEGGMDIEEVAHNTPEKIIKVFVDPLAGLTDAQAIELAKGIGVPEASIPQAVDTFKKLYTCYMETDASLAEINPLILEGNGNIKALDAKFNFDSNALFRHPEIVAYRDLDEEDADEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGAEPANFLDVGGGATTEKVTEAFKIMLKNPKVKGILVNIFGGIMKCDTIATGVVAAAKEVNLSVPLVVRMKGTNEDLGKKILAESGLPIISADTMAEAATKIVAEVK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: RS9_MYCPU
Sequence: MAISYQLKSPAFRGLGRRKSSVARVILLKGSGKFTINKREAKEYLKSDIYIKDALQPFDLTQTNNTFDIRVTVRGGGLAGQAGAIRLGIARALLEISADYRSVLKEAKMLTRNTKVKERKKPGLRKARKARQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: BASR_ECOLI
Sequence: MKILIVEDDTLLLQGLILAAQTEGYACDSVTTARMAEQSLEAGHYSLVVLDLGLPDEDGLHFLARIRQKKYTLPVLILTARDTLTDKIAGLDVGADDYLVKPFALEELHARIRALLRRHNNQGESELIVGNLTLNMGRRQVWMGGEELILTPKEYALLSRLMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKARIRTVRGFGYMLVANEEN
What is the function of this protein?
Member of the two-component regulatory system BasS/BasR.  BasR induces the transcription of the ugd, ais, arnBCADTEF and eptA-basRS loci, all involved in resistance to polymyxin (By similarity).
What are the official names of this protein?
Transcriptional regulatory protein BasR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYG_MYCPA
Sequence: MHRLVASVIDTVVNLAKRRGFVYPSGEIYGGTRSAWDYGPLGVEFKENIKRQWWRSVVTGREDVVGLDSSIILPRQVWVASGHVEVFHDPLVESLITHKRYRADHLIEAYEAKHGHPPPNGLADIRDPDTGEPGRWTEPREFNMMLKTYLGPIETEEGLHYLRPETAQGIFVNFANVVTTARKKPPFGIGQIGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTAKEWHQYWIDTRLQWYVELGIDPQNLRLFEHPADKLSHYSDRTVDIEYKFGFAGNPWGELEGVANRTDFDLSTHSKHSGVDLSFYDQATDSRYIPYVIEPAAGLTRSFMAFLIDAYVEDEAPNAKGKMEKRAVLRLDPRLAPVKAAVLPLSRHADLSPKARDLAAELRRFWNIEFDDAGAIGRRYRRQDEIGTPFCVTVDFDSLEDNAVTVRRRDDMSQERIGMDAVADYLSARLKGC
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPB_MYCGA
Sequence: MFASFTPTEEKNVLSKYSRNLNDEIARNAIDPTIGREEEIRRLIEILSRKNKNNPVLIGEPGVGKTAIVEGFARKIVNGDVPDNLKDVEVVELSLSSLIAGTQFQGSFEERLNKILKEVKNSSGKVILFIDEIHQLVGMGKNSSNSAMDAANILKPMMARGEIKVIGATTIDEYRKYIEKDGALERRMQKILVDEPTKQEALTIMRGLRERWEAFHKVRIFDDALVAAVEMSARYISDRYLPDKAIDLIDEAAAKIKTLIHSLPPELDNIKQKIIHLSTELAALEREKKENHSNVRLGRIEQLKKEIKDFTNKQNELTVKWTQQKTIYECINKLKEEVTNLTAEIERLQAKGEYTQASKLLYLEIPKRQEEIEKKTKELSEFTDNLIKTSISRVEIAEVISQATKIPLSKLVASEQQKLLNLKNDLSKYIKGQDHAIKNVSDAVLRGRAQINDPNRPIGSFLFLGPTGVGKTEVAKKLAYCLFDNEKAMVRIDMSEFMERHSVDKLIGSPPGYIGYDQPGVLSDAIRTKPYAVVLFDEIEKAHPDVLNILLQILDDGQLTDNHNRLVNFKNTIIIMTSNIGAEHILANNPAKTIEELKRKIRPELLNRIDELITFKALNDKDLSAIAQKLLSDLSDRIKKQQINITFDKKIVENVVKHGSNTVFGARPLKRYIQREVENFLAKKIIENKLEKNKSYVCTFNAETNEYTLVNLRKAVS
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEP_HELPJ
Sequence: MKFLRSVYAFCSSWVGTIIIVLLVIFFIAQAFIIPSRSMVGTLYEGDMLFVKKFSYGIPIPKIPWIELPVMPDFKNNGHLIEGDRPKRGEVVVFIPPHEKKSYYVKRNFAIGGDEVLFTNEGFYLHPFESGNDKDYISKHYPNALTKEFMGKIFVLNPYKSKHPGIHYQKDNETFHLMEQLATQGAEANISMQLIQMEGEKVFYKKINHDEFFMIGDNRDNSSDSRFWGSVAYKNIVGSPWFVYFSLSLKNSLEVDAENNPKKRYLVRWERMFKSVEGLEKIIKKEKATH
What are the official names of this protein?
Signal peptidase I, SPase I, Leader peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: ARGB_BART1
Sequence: MDDAKNSAVDVLEKQAAFLSSALPYMQKYENETVVVKYGGHAMGDPALGRAFARDIALLKQSGINPVVVHGGGPQIAEILMKMGIESRFENGLRVTDERIVEVVEMVLAGSINKEIVALINAEGEWAIGLCGKDGNMVFAEKAYRTVIDPDSHIERVLDLGFVGEPIEVDRTLLDLLACSEMIPVLAPVAPGRDGKTYNINADIFAGAIAGALEAKRLLFLTDVPGVLDKQGKLLKELTVSEAEKLIKNGTISGGMIPKVETCVKALQNGVEGVVILNGKTPHSVLLELFTEQGVGTLIVS
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_BORGP
Sequence: MKKKSSDFCFGSERKAQLSEFLENLSIDFNNFDLLNTALSHSSYSNELDQKADNNERLEFLGDSVLNLIITDHLYKTYPNKSEGELSKARSYIVSEDSLSSIAREIDLGSYILLGRGEESNDGRNKKGILADAIEAFVGAIYLDSGFSMATEFVVGLFDMYIRLMFNRGDFKDYKSLLQEYVQKKYKISPSYKLDKEIGPDHDKVFCVELYVGEKFISNGKGKSKKEAEMRAAEVALKAMEDINL
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_SHEWM
Sequence: MKQIQVDLGVRSYPIVIGRNLMSCGEHFARFLQDKKILIVTNETVAPLYLEKLELQLSSFDCVEPVILPDGEQYKTLAQMDSIFTSLLQQNSGRDTVLIALGGGVIGDMTGFAAASYQRGIDFIQIPTTLLAQVDSSVGGKTAVNHPLGKNMIGAFYQPKLVVIDTDCLSTLPAKEFSAGMAEVIKYGIIWDSEFFSWLENNVERLKTLDDEALAYAIGRCCEIKADVVAEDETEQGVRALLNLGHTFGHAIEAEMGYGVWLHGEAVAAGTVLAASTASRMGLIDGSIVCRITKLFEAFDLPVSPPDSMNFEQFIKHMRRDKKVLKGQVRLVLPEAMGQAGVYSEVSDELLEDVIRCA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_STRPG
Sequence: MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSHWITNRQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKVMFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RADI_BOVIN
Sequence: MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYNKEIHKPGYLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLRQIEEQTMKAQKELEEQTRKALELDQERKRAKEEAERLEKERQAAEEAKSALAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEEATEWQHKAFAAQEDLEKTKEELKTVMSAPPPPPPPPVIPPTENEHDEHDENNAEASAELSNDGVMNHRSEEERVTETQKNERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAM
What is the function of this protein?
Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane.
What are the official names of this protein?
Radixin.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cleavage furrow. Cell projection, microvillus. Note=Highly concentrated in the undercoat of the cell-to-cell adherens junction and the cleavage furrow in the interphase and mitotic phase, respectively.
Protein: ARF_VIGUN
Sequence: MGLSFTKLFSRLFAKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRDRVVEARDELHRMLNEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRQRHWYIQSTCATSGEGLYEGLEWLSNNIASKA
What is the function of this protein?
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
What are the official names of this protein?
ADP-ribosylation factor.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: CYSC_SHIDS
Sequence: MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: ARPC5_CAEEL
Sequence: MYNTDYKKYNVDIFHPAHFEDIQEESADCGPNVQEVRQFLESNRLEYALQSVLLNPPFGHSEQELKNRAVLLVAEVIHAFRQTDIEESVHKLSNENGDILMKYIYKAMQLCSDSATCLSLLLWHSQLVSKFGQGSIVRVLSNRQRL
What is the function of this protein?
Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
What are the official names of this protein?
Probable actin-related protein 2/3 complex subunit 5, Arp2/3 complex 16 kDa subunit, p16-ARC.
What is the protein family that this protein belongs to?
Belongs to the ARPC5 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: SCAMP_CANLF
Sequence: MLKVSRVSSEGLISLSITEAPDLKIRDPKIEKLYLPVFYLNAHIYLNALSTLLNSHCGENCFHGYEQLQNATFPVWRNIFIYINRVRNIKRQGGGGGVSGKGEMKQCFLS
What is the function of this protein?
Putative sphingolipid-gated calcium channel.
What are the official names of this protein?
Putative protein SCAMPER, Sphingolipid calcium release-mediating protein of the endoplasmic reticulum, SCaMPER.
What are the subcellular locations of this protein?
Sarcoplasmic reticulum. Sarcoplasmic reticulum membrane; Single-pass membrane protein. Note=Localizes to the sarcotubular junctions where T tubules connect to the sarcoplasmic reticulum.
Protein: GAP1_ORYSI
Sequence: MLGHLVGLVKVRVVRGVNLAVRDLRSSDPYVIVRMGKQKLKTRVIKKTTNPEWNDELTLSIEDPAVPVRLEVYDKDTFIDDAMGNAELDIRPLVEVVKMKIEGVADNTVVKKVVPNRQNCLAEESTIYISEGKVKQDVVLRLRDVECGEIELQLQWVDIPGSKGV
What is the function of this protein?
Mediates the transient calcium-dependent interaction of PYR/PYL/RCAR abscisic acid (ABA) receptors with the plasma membrane and thus regulates ABA sensitivity (By similarity).  Stimulates the GTPase/ATPase activities of YchF1, and regulates its subcellular localization.  Promotes tolerance towards salinity stress by limiting the accumulation of reactive oxygen species (ROS).  Promotes resistance to bacterial pathogens (By similarity).
What are the official names of this protein?
GTPase activating protein 1, OsGAP1, G-protein binding protein 1, OsGPBP1.
What is the protein family that this protein belongs to?
Belongs to the plant CAR protein family.
What are the subcellular locations of this protein?
Cell membrane. Nucleus. Cytoplasm, cytosol. Note=Localized mainly in the cytosol under NaCl treatment, but translocates to the plasma membrane upon wounding.
Protein: PRSA1_LISIN
Sequence: MTKLKKVMISLVAATLLLLAGCGSSAVVKTDAGNVTQDELYEAMKTTYGNEVVQQLTFKKILEDKYTVTEKEVNAEYKKYEEQYGDSFESTLSSNNLTKTSFKENLEYNLLVQKATEANMNVSESKLKTYYKTWEPNITVRHILVDDEATAKEIQTKLKNGEKFADLAKEYSTDTATSTNGGLLDPFGPGEMDETFEKAAYALKNKDDVSGIVKSTYGYHLIQLVKKTEKGTYAKEKANVKAAYIKSQLTSENMTAALKKELKAANIDIKDSDLKDAFADYTSTSSSSSTSTSN
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA 1.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: VILI2_ARATH
Sequence: MSTKVLDPAFQGAGQKPGTEIWRIENFEAVPVPKSEHGKFYMGDTYIVLQTTQNKGGAYLFDIHFWIGKDTSQDEAGTAAVKTVELDAVLGGRAVQHREIQGHESDKFLSYFKPCIIPLEGGVASGFKTVEEEVFETRLYTCKGKRAIRLKQVPFARSSLNHDDVFILDTEEKIYQFNGANSNIQERAKALEVVQYLKDKYHEGTCDVAIVDDGKLDTESDSGAFWVLFGGFAPIGRKVANDDDIVPESTPPKLYCITDGKMEPIDGDLSKSMLENTKCYLLDCGAEIYIWVGRVTQVDERKAASQSAEEFLASENRPKATHVTRVIQGYESHSFKSNFDSWPSGSATPGNEEGRGKVAALLKQQGVGLKGIAKSAPVNEDIPPLLESGGKLEVWYVNGKVKTPLPKEDIGKLYSGDCYLVLYTYHSGERKDEYFLSCWFGKKSIPEDQDTAIRLANTMSNSLKGRPVQGRIYEGKEPPQFVALFQPMVVLKGGLSSGYKSSMGESESTDETYTPESIALVQVSGTGVHNNKAVQVETVATSLNSYECFLLQSGTSMFLWHGNQSTHEQLELATKVAEFLKPGITLKHAKEGTESSTFWFALGGKQNFTSKKASSETIRDPHLFSFAFNRGKFQVEEIYNFAQDDLLTEDIYFLDTHAEVFVWVGQCVEPKEKQTVFEIGQKYIDLAGSLEGLHPKVPIYKINEGNEPCFFTTYFSWDATKAIVQGNSFQKKASLLFGTHHVVEDKSNGGNQGLRQRAEALAALNSAFNSSSNRPAYSSQDRLNESHDGPRQRAEALAALSSAFNSSSSSTKSPPPPRPVGTSQASQRAAAVAALSQVLVAENKKSPDTSPTRRSTSSNPADDIPLTEAKDEEEASEVAGLEAKEEEEVSPAADETEAKQETEEQGDSEIQPSGATFTYEQLRAKSENPVTGIDFKRREAYLSEEEFQSVFGIEKEAFNNLPRWKQDLLKKKFDLF
What is the function of this protein?
Ca(2+)-regulated actin-binding protein.  Involved in actin filaments bundling.  Caps the barbed end of actin filaments and is able to sever them in a calcium-dependent manner.  Required for the construction of actin collars in pollen tubes.  Acts redundantly with VLN5 (AC Q9LVC6) to generate thick actin filament bundles and to regulate polarized pollen tube growth (PubMed:23715472).  Acts redundantly with VLN3 (AC O81645) to regulate directional organ growth and in sclerenchyma development (PubMed:22209875, PubMed:22563899).
What are the official names of this protein?
Villin-2.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Present in the apical and subapical regions of pollen tubes.
Protein: DERK_MYCS2
Sequence: MTKLFNDPARFTEDMLVGFLDANSRYVVGVPGGVVRAQTTRPGKVAVVIGGGSGHYPAFCGTVGPGFADGAVVGNIFTSPSAEEAASVARAAHSDAGVLLTTGNYAGDVMNFNLAVDQLRSEGIEAQYFAVTDDVASAERGQEAKRRGIAGDFTVFKCASAAAEEGLDLAGVVRVAEAANAATRTLGVAFDGCTLPGADHPLFTVPEGHMGLGLGIHGEPGVSEEKMPTAAGLAATLVDGVLGDRPDAPEKRIAVILNGLGRTKYEELFVVWGEVSRLLRDRGYTIVEPEVGELVTSLDMAGCSLTVMWLDEELERYWAAPADTPAYKKGAAQQHVSGERRSEATARSASSGPKLAELSDEDGRAGARLVARAFDAMAEALADAEEELGRIDAVAGDGDHGRGMVKGSSAAREAAASALSEGAGQGSVLNAAGKAWAAKAGGTSGVLWGALLTALGARLGDTGRPDSSVIAAGVRDAYDALIRLGGAAPGDKTMLDAMLPFTEELERRVAQDESWQSAWRAAADVATEAARATADLRPKIGRARPLAERSVGTPDAGATSLALCARTVADCVTLSTQGEN
What is the function of this protein?
Catalyzes the phosphorylation of D-erythrulose to D-erythrulose-4P.  Involved in the degradation pathways of erythritol and D-threitol, that allow M. smegmatis to grow on these compounds as the sole carbon source.
What are the official names of this protein?
D-erythrulose kinase.
Protein: OTC_METS3
Sequence: MSNLLSVCDIKDEVLDILELAKNFKEGKMEEKPLAGKSLAMIFQKSSTRTRVSFDVGMYQLGGQALFLSSSELQMGRGEPIPDTAKVLSRFVDGIMIRAIEHDDVVELAKYSDVPVISGLTNLEHPCQALADMLTIQEHLGKLEGKKLCFVGDGNNVCNSLLLMAPLVGMDMSVACPEGYEPNEDIVNMAKKLAEEHNKEITISSDLKVALDNVDVVYTDVWVSMGDEKEAEQRQKDFAPYQVNSNLMSLANDGAIFMHCLPAIRGQEVSGEVIDGPQSVVFDEAENRLHAQKAVLYHFLK
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRR_STAEQ
Sequence: MSERIILDDAAIQRTITRIAHEILEYNKGTKDLVLLGIKTRGAFLAHRIQDKINSIEQQLVPTGTIDITHFRDDVDKVVQQADQRAFDINVDINNKVVVIIDDVLYTGRTVRASLDAILLHTRPIKIGLAALVDRGHRELPIRADFVGKNIPTARDESVSVYLEEIDDRNAVVIE
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: PYRF_SALPA
Sequence: MTFTASSSSCAITESPVVVALDYHERDKALAFVDKIDPRDCRLKVGKEMFTLFGPQLVRDLQQRGFDVFLDLKFHDIPNTTARAVAAAADLGVWMVNVHASGGARMMAAARDALAPFGKDAPLLIAVTVLTSMETSDLRDLGVTLSPAEHAERLARLTQQCGLDGVVCSAQEAVRFKQVFGAAFKLVTPGIRPAGSEAGDQRRIMTPEQALSAGVDYMVIGRPVTQSVDPAQTLKDINASLKREA
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: HRCA_GEOSE
Sequence: MLTERQLLILQVIIDDFIRSGQPVGSRTLSKKHEIALSSATIRNEMADLEELGYIEKTHVSSGRVPSEKGYRYYVDHLLSPQRLTKDDIQKIKSIFAERIYELEKVVQKSAQILSDLTNYTSIALGPAVKENKLKRIQIIPLNQQTAVAIIVTDTGHVENHVITVPASVNPSDLEKMVNIFNERLIGVPLVDLKDKIYKKVADVLRKHIRNYDSMLQTIVETLDIPQEEKMFFAGKTNMLNQPEFNDIQKIRPLMKMIEQEKDFYRLLRKHNRKGIQVTIGRENQLSEMENCSLITATYSIGDEQLGTIAILGPTRMEYSRVITILNRVASDLSIALTKWYQNG
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: PURA_FRAP2
Sequence: MSNIVIVGAQWGDEGKGKIADTLAEKSDLVVRYQGGNNAGHTLVVNGKKTFLHLIPSGVLHKHTKCVIGHGVVVDPIALDTEITRLQDTGIEISANNLFVSESCTVITSYHKLLDAVRENSTTEKIGTTGKGIGPAYEDKVSRKGIKFKHLFDKDVLRSRLALSLAEKETLFKDLYKVEYPSLEEEFERLYTLGQKLKQYSADTFSIIDQAVSTGKNVVYEGAQGVLLDIDYGTYPFVTSSNTSVAGVYSGATTAGHNLDHVIGITKAYTTRVGEGPFPTELFDDTGLFIQKKGGEIGVTTGRIRRCGWLDLPLLKYSAKCSNLTSIALTKVDVLSDLDTLKICIGYKYEGKEIFCAYPGIDLYKVEPILVDMEPFSLDEVVTKENMPSALKTYLRTIENHIGIPISSLAYGPSREQILFFEDYFKKG
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_SINFN
Sequence: MTKSPIGGNRSGRKLGQKVKKGKLKASSRRWLERHINDPYVQRAQLEGYRARAAFKLLEIDEKHKILAGARRIIDLGAAPGSWSQIAAKVTNSTDADPRVAAIDFLEMDPIPGVRFLQLDFLDPEAPEKLKEAIGGTPDLVLSDMAAPTTGHRQTDHLRTMHLCEVAAHFAVDVLAKGGHFLAKTFQGGTERDLLNMLKQNFSQVIHVKPASSRTESVEMFLLAKGFKGRRKAETEEPAEDAAAE
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_CHLMU
Sequence: MHEAFTIEQLPQSWQEQLKDEWSQPYWSQLLTFLKSEYANATVYPKKEHVFSALRSTPFDQVKVVILGQDPYHGEGQAHGLSFSVPKGQALPPSLRNIFQELQADLGIRNETGCLQTWADQGVLLLNTVLTVRAGEAFSHAGRGWEHFTDAIVTKLIQNRTHIIFVLWGSAARKKCDLLFQTKHQHAILACPHPSPLAAHRGFFGCCHFSKINYLLKKQGKPMINWKIA
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPGP_MYCVP
Sequence: MRVRRLVMLRHGQTEYNAGSRMQGQLDTDLSDLGREQAVAAAEVLAKRQPLLIVSSDLRRALDTAVALGDRSGQPVSIDTRLRETHLGDWQGMTHLEVDAAAPGARLAWRDDARWAPHGGESRVDVADRSLPLVHELVTQQTDWGAAGSDRPVVLVAHGGLIAALTAALLGLPVDNWPVLGGMGNASWVQLAGHTRADGDPGAFADIRWRLDVWNASAQVANDVL
What is the function of this protein?
Involved in the biosynthesis of mycobacterial methylglucose lipopolysaccharides (MGLP).  Catalyzes the dephosphorylation of glucosyl-3-phosphoglycerate (GPG) to glucosylglycerate.
What are the official names of this protein?
Glucosyl-3-phosphoglycerate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family.
Protein: RL3_COREF
Sequence: MSENEIKGILGTKLGMTQIFDEENRVIPVTVVEAGPCVVSQIRTVETDGYNAIQIAYGEIDPRKVNQPLTGHFKKAGVTPRRHVTEIRMDDVSGYEVGQDVTVEIFNDVKFVDVTGTSKGKGYAGAMKRHGFAGQGAGHGNQAAHRRVGGIGAAATPGRIFKGKRMAGRMGNDRVTTQNLKVQKIDADANLILIKGAIPGNRGGIVTVKTAVKGGAHA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RS43_ARATH
Sequence: MARGLKKHLKRLNAPKHWMLDKLGGAFAPKPSSGPHKSRECLPLVLIIRNRLKYALTYREVISILMQRHIQVDGKVRTDKTYPAGFMDVVSIPKTNENFRLLYDTKGRFRLHSIKDEEAKFKLCKVRSIQFGQKGIPYLNTYDGRTIRYPDPLIKPNDTIKLDLEANKIVEFIKFDVGNVVMVTGGRNRGRVGVIKNREKHKGSFETIHIQDSTGHEFATRLGNVYTIGKGTKPWVSLPKGKGIKLTIIEEARKRLASQQAA
What are the official names of this protein?
40S ribosomal protein S4-3.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
What are the subcellular locations of this protein?
Cytoplasm.