PharMolix/UniProtQA huggingface dataset:
Protein: MTC6_KLULA
Sequence: MLLYFLVVAPLWMLSGLVRAEVWPSFSDEMIYAIRSQRDLMQNISIDQVPLPGLALKNSLPGSITSNETESLTTILSLLHHGIQSFRVDLTFNSSAGEWFLEGTNIRFVKMLNTVNLFVMATNTNLDANILTILLRFDNDTLRNSNAIKEANFTAILEEGLSPGYVYSIADLERDRELNQTLSINGYSDTGWVGLSRFLFDVKKRVVFGFLNGAELFSEDDQDNLVFPPETFHYVTANNITCPLNTVEDIMRVSQIQWRFLEGNFSYENYLHYLECGYSLILTNPIDTRNDSSQGTSLQRHLSSLLLWSWNATAPDDKLDESEDSDDSESSSTSQYVAYRCGAFSYNDYEDLDPFKIGNCYRNLPYLCRFSDRAYFWNISEDTGTYFESDDKDMCPTGYKFGVPRTPLQQRSLRIHLNDMDIDNLDFWIDINSISVSNCWITGGPYASCPYQKYGSRRNYIAMTVPTSAIALVLLLVIFYFNWVHVPIQDNRNNWKRIINAYSKEEVEGVPS
What is the function of this protein?
May be involved in telomere capping.
What are the official names of this protein?
Maintenance of telomere capping protein 6.
What is the protein family that this protein belongs to?
Belongs to the MTC6 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: ISPH_ACTP2
Sequence: MNILLANPRGFCAGVDRAISIVELALEIHGAPIYVRHEVVHNRFVVDGLKAKGAVFVEELDEVPDGAIVIFSAHGVSQEVRQEAKRRGLKVFDATCPLVTKVHMQVARASKKGTKAILIGHEGHPEVIGTMGQYDNQDAGIFLVESVEDIAKLPVSSQDDLTFMTQTTLSIDDTSDVIEALKEKYPAIQGPRKNDICYATTNRQQAVRELAKQSQLVLVVGSKNSSNSNRLAELASRMGVPSKLIDGPQDIDPSWLDGVETIGITAGASAPEVLVQSVVEHLKTLGVTGVSNLEGCEENMVFEVPKELRIHEVK
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: MHPA_MYCGI
Sequence: MTEQTDVDVVIVGAGPAGLTLANILGLEGVRVLVVDERDKLIDYPRGVGLDDESLRTFQAIGLVDRVLPHTVPNQILRFFDAKRNLLAEMAPPDARFGWPKRNGFVQPMVDAELFGGLQRFDNVEVRFGHRMHQCTQTTDRVEVEFDGGQASVSARYVVGCDGGRSVTRRLMGVSFDGTTSSTRWLVVDIANDPLGHPNSEVGADPRRPYVSIAIAHGIRRFEFMIHPDETDEEADDPAFVRRMLGQLIPYPERVDMIRHRVYTHHSRIAGSFREGRLMLAGDAAHLMPVWQGQGYNSGIRDAANLGWKLAAVVTGRAGEELLDTYDVERRKHARAMIDLSTMVGRVISPTNRKVAALRDRVIHAASAVPSLKRYVLEMRFKPMPRYQQGAVLHHAHAAPNSPTGTLFIQPRVDTRDTQNALLDDVLGTGFAVVCWSNNLRAVLGEEAFGRWKALGAKFVEVRPMSQLRWPGHDDPDVAVIGDRTGALKAWFDVHTESVLFVRPDRCIAAACIAQRAPEISEGLFAALHLTSGAHLTQGGGTDGEKPDRAVLHVAQPAAESSGTGAGTS
What is the function of this protein?
Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI).
What are the official names of this protein?
3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase, 3-HCI hydroxylase, 3-HPP hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the PheA/TfdB FAD monooxygenase family.
Protein: MLE_MIZYE
Sequence: PKLSQDEIDDLKDVFELFDFWDGRDGAVDAFKLGDVCRCLGINPRNDDVFAVGGTHKMGEKSLPFEEFLPAYEGLMDCEQGTFADYMEAFKTFDREGQGFISGAELRHVLTALGERLTDEEIDEIISLTDLQEDLEGNVKYEDFVKKVMAGPYPDK
What is the function of this protein?
In molluscan muscle, calcium regulation is associated with myosin rather than with actin.  Muscle myosin contains two types of light chains: the catalytic light chain, essential for ATPase activity, and the regulatory light chain, a calcium-binding protein responsible for Ca(2+) dependent binding and Ca(2+) dependent Mg-ATPase activity.
What are the official names of this protein?
Myosin, essential light chain, adductor muscle, Sulfhydryl light chain, SHLC.
Protein: GLYA_SHEPA
Sequence: MLKKDMNIADYDPQLFAAIEDETRRQEEHIELIASENYCSPRVIEAQGTQLTNKYAEGYPGKRYYGGCEHVDIVEELAISRAKELFGATYANVQPHSGSQANAAVFMALLQGGDTVLGMSLAHGGHLTHGSHVSFSGKLYNAVQYGIDETTGQIDYAEVERLAVEHKPKMIIAGFSAYSGIIDWGKFREIADKVGAYLFVDMAHVAGLVAAGIYPNPMPHAHVVTTTTHKTLAGPRGGLILSSINDEDIYKKLNSAVFPGGQGGPLMHVIAAKAVAFKEALDPEFTTYQEQVVVNAKAMARTFIERGYNVVSGGTDNHLFLLDLISKDITGKDADAALGNANITVNKNSVPNDPRSPFVTSGLRIGSPAITRRGFGEEESVQLTHWMCDVLDDISDLAVSERVKGQVLELCAKFPVYG
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HGL2_ENTH1
Sequence: MKLLLLNILLLCCLADKLNEFSADIDYYDLGIMSRGKNAGSWYHSYTHQYDVFYYLAMQPWRHFVWTTCETTKGNKECYKYIINEDHNLNAQQLNNIKNLDKQDFCQKEYAYPIEKYEVDWDNVPVDEQQIESVDINGKTCFKYAAKRPLAYVYLNTKMTYATKTEAYDVCRMDFIGGRSITFRSFNNENKDFIDQYNTNTTSKCIIDVHKNNVNTHLAIILGITDSTVIKSLQEKLSVLSQLTTVDGVTIYYLKGDSYATDNIKLKDLKYETLVKYTAGQGQVDPLVNIAKNDLFKMISDKKIKRGTMVVLMDNALGSEFNAETEFDRKNISVHTVVLNRNKDSKITYSALKLVSLGPHYHEFTSNSEVSTTIDELFKGIRANLTERCDRDKCSGFCDAMNRCTCPMCCENDCFYTSCDVETGSCIPWPKAKPKAKKECPATCVGLYECKDLEGCVVTKYNASCEPKVKCMVPYCDDDNNLKEVCKQKANCEADQKPSSDGYCWSYTCDETTGFCKKYKHGNLCTGKTTNCQEYVCDSEQRCTVQEKVCVKTSPYIEMSCYVAKCNLNTGMCENRLSCDTYSSCGGDSTGSVCKCDASTGNQCKCNKVENGNYCDSSKHEICDYTGDKPKCIVSECTEDLVRDGCLIKRCNKTSKTTYWENVDCSNTKIEFAQDGKSETMCKPYYSATCLNGQCVVQAVGDVSNVGCGYCSMGTDNVITYHDDCDSRKSQCGNFNGKCQPNGDNSYSCVFEKDKTSSKSDNDICAECSSLTCPADTTYRTYTYDSKTGTCKATVKPTPSCSVCEKGKFVEKCKDQKLERKVTLEDGKEYQYNIPKDCVNEQCIPRTYVDCLANDDNFGEIYKFYLPCQAYVTATYHYSSLFNLTSYKLHLPQSEEFMKEADKEAYCTYEITTRECKTCSLTETKEKVEEIDLCAEETKNGGVPFKCKNNNCIIDPNFDCQPIECKIQEIVITEKDGIKTTTCKDTGKTTCDTNNKRIEDARKAFIEGKEGIEQVECASTVCQNDNSCPIIADVEKCNQNTEVDYGCKAMTGECDGTTYLCKFVQLTDDPSLDSEHFRTKSGVELNNACLKYKCVESKGSDGKITHKWEIDTERSNIDPKPRNPCETATCDQTTGETIYTKKTCTVSEEFPTITPNQGRCFYCQCSYLDGSSVLTMYGETDKEYYDLDACGNCRVWNQTDRTQQLNNHTECILAGEINNVGAIAAATTVAVVVVAVVVALIVVSIGLFKTYQLVSSAMKNAITTTNENAEYVGADNEATNAATYNG
What is the function of this protein?
Lectin which binds galactose and N-acetyl-D-galactosamine of host glycoproteins and thus mediates adhesion to host cells (PubMed:2536731) (Probable).  Mediates adherence to host colonic mucins, an essential step for pathogenic tissue invasion (Probable).
What are the official names of this protein?
Galactose/N-acetyl-D-galactosamine lectin heavy subunit 2, Gal/GalNAc lectin heavy subunit 2, 170 kDa surface lectin, Galactose and N-acetyl-D-galactosamine-inhibitable adherence lectin.
Protein: PTH_METM7
Sequence: MYEQAIVIRNDLKMGKGKMAAQACHASIQAFLHAQKISSSAVSGWMNEGQKKVVLKVNSEKELLEIFKNVNIEGLPCSLIRDAGRTQVEPGSLTAVGIGPEKEEKISKVTKDLKLL
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNX14_HUMAN
Sequence: MVPWVRTMGQKLKQRLRLDVGREICRQYPLFCFLLLCLSAASLLLNRYIHILMIFWSFVAGVVTFYCSLGPDSLLPNIFFTIKYKPKQLGLQELFPQGHSCAVCGKVKCKRHRPSLLLENYQPWLDLKISSKVDASLSEVLELVLENFVYPWYRDVTDDESFVDELRITLRFFASVLIRRIHKVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEFLQQAALEEYGPELHVALRSRRDELHYLRKLTELLFPYILPPKATDCRSLTLLIREILSGSVFLPSLDFLADPDTVNHLLIIFIDDSPPEKATEPASPLVPFLQKFAEPRNKKPSVLKLELKQIREQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRGAESPTRNSKLNRGSLSLDDFRNTQKRGESFGISRIGSKIKGVFKSTTMEGAMLPNYGVAEGEDDFIEEGIVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKERIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMKEKGQHLEPFIMNFINSCESPKPKPSRPELTILSPTSENNKKLFNDLFKNNANRAENTERKQNQNYFMEVMTVEGVYDYLMYVGRVVFQVPDWLHHLLMGTRILFKNTLEMYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLLVKCIGEETKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPELNKVQKEVTSVTSWM
What is the function of this protein?
Plays a role in maintaining normal neuronal excitability and synaptic transmission.  May be involved in several stages of intracellular trafficking (By similarity).  Required for autophagosome clearance, possibly by mediating the fusion of lysosomes with autophagosomes (Probable).  Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2), a key component of late endosomes/lysosomes (PubMed:25848753).  Does not bind phosphatidylinositol 3-phosphate (PtdIns(3P)) (PubMed:25848753, PubMed:25148684).
What are the official names of this protein?
Sorting nexin-14.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Cell projection, dendrite.
Protein: PUR9_YERPG
Sequence: MQQRRPIRRALLSVSDKAGIIEFAQALSQRGIELLSTGGTARLLADAGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDGIMAQHGIQPIDIVVVNLYPFAQTVARPDCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYPAIITELDNNDGSLTYPTRFNLAIKAFEHTAAYDSMIANYFGTLVPPYHGDTEQPSGHFPRTLNLNYIKKQDMRYGENSHQQAAFYIEEDVKEASVATAQQLQGKALSYNNIADTDAALECVKEFSEPACVIVKHANPCGVAIGDSILAAYERAYQTDPTSAFGGIIAFNRELDAATASAIISRQFVEVIIAPTVSSDALALLAAKQNVRVLTCGQWQARSAGLDFKRVNGGLLVQERDLGMVTAADLRVVSKRQPTEQELRDALFCWKVAKFVKSNAIVYARDNMTIGIGAGQMSRVYSAKIAGIKAADEGLEVAGSAMASDAFFPFRDGIDAAAAVGITCVIQPGGSIRDDEVIAAADEHSIAMIFTDMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: PTH_VIBVY
Sequence: MSQQIKLLVGLANPGPEYAKTRHNAGAWVVEELARVHNITLKNEAKFYGLTGRIVMNGQELRLLIPTTFMNLSGKAIAALAKFYQIQPEEIMVAHDELDLPPGIAKFKKGGGHGGHNGLRDTISKLGNNKEFYRLRIGIGHPGHKDKVAGFVLGKAPASEQSLLDATVDESVRCLDILIKDGLSKAQNRLHTFKAE
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPOL_PYRGL
Sequence: MILDADYITEDGKPIIRIFKKENGEFKVEYDRNFRPYIYALLKDDSQIDEVKKITAERHGKIVRIVDVEKVKKKFLGRPIEVWKLYFEHPQDVPAIRDKIREHPAVVDIFEYDIPFAKRYLIDKGLIPMEGDEELKLLAFDIETLYHEGEEFAKGPIIMISYADEEGAKVITWKKVDLPYVEVVSSEREMIKRFLKVIREKDPDVIITYNGDSFDLPYLVKRAEKLGIKLPLGRDGSEPKMQRLGDMTAVEIKGRIHFDLYHVIRRTINLPTYTLEAVYEAIFGKPKEKVYAHEIAEAWETGKGLERVAKYSMEDAKVTYELGREFFPMEAQLSRLVGQPLWDVSRSSTGNLVEWYLLRKAYERNELAPNKPDEREYERRLRESYAGGYVKEPEKGLWEGLVSLDFRSLYPSIIITHNVSPDTLNREGCREYDVAPEVKHKFCKDFPGFIPSLLKRLLDERQEIKRKMKASKDPIEKKMLDYRQRAIKILANSYYGYYGYAKARWYCKECAESVTAWGREYIEFVRKELEEKFGFKVLYIDTDGLYATIPGAKPEEIKRKALEFVEYINAKLPGLLELEYEGFYVRGFFVTKKKYALIDEEGKIITRGLEIVRRDWSEIAKETQAKVLEAILKHGNVEEAVKIVKEVTEKLSKYEIPPEKLVIYEQITRPLHEYKAIGPHVAVAKRLAARGVKVRPGMVIGYIVLRGDGPISKRAILAEEFDPRKHKYDAEYYIENQVLPAVLRILEAFGYRKGDLRWQKTKQTGLTAWLNVKKK
What is the function of this protein?
In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' exonuclease activity.
What are the official names of this protein?
DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
Protein: ENO_ARTS2
Sequence: MALIDAIHAREILDSRGNPTVEVEVLLSDGQIGRAAVPSGASTGEHEAVELRDGDKGRYLGKGVQKAVDAVIDQIAPALTGFDATDQRSIDQAMIDLDGTPNKSKLGANAILGVSLAVANAAAASADLPLYKYLGGPNAHVLPVPLMNILNGGSHADSDVDIQEFMIAPIGAETFSEGLRWGVEVYHNLKSVLQAKGLSTGLGDEGGFAPNLPSNRAALDLIQEAIKNAGYIPGKDIALALDVASSEFFKDGAYQFEGKALSATEMSAYYAELVADYPLVSIEDPLDENDWEGWKTLTDAIGDKVQLVGDDLFVTNPSILQRGIDTATANSLLVKVNQIGSLTETLDAVSLAQRAGYTTITSHRSGETEDTTIADIAVATNAGQIKTGAPARSERVAKYNQLLRIEEELDDAARYAGRSAFPRFKG
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: T2P2_NEIGO
Sequence: MNIIDAIINLANNPVVGVESHSQSNNRANQAGDALEEYVKDLFSGSFNLNETQRIARHAKVFSYLGNNSNPPDAMLRNGDAIEVKKIESKDSALALNSSHPKSKLSVDDSMLTKACKDAEKWEEKDIIYIVGVVDKKKNLKHLAMVYGIDYCADAECYLKIKNQIKEGIGNIGGIQFAETKELGRVNRIDPLNITYLRVRGMWGIENPWFVFNYIYQRNMEKSFNFMAIINEDKWNSFNNTDKLLAIQDSKLAISDIKIKNPNNPARLRNAKLITYHL
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-GGCC-3' and cleaves after G-2.
What are the official names of this protein?
Type II restriction enzyme NgoPII, R.NgoPII, Endonuclease NgoPII, Type-2 restriction enzyme NgoPII.
What is the protein family that this protein belongs to?
Belongs to the NgoPII type II restriction endonuclease family.
Protein: HSLV_BACC0
Sequence: MGNFHATTIFAVHHNGECAMAGDGQVTMGNAVVMKHTARKVRKLFQGKVLAGFAGSVADAFTLFEMFEGKLEEYNGNLQRAAVEMAKQWRGDKMLRQLEAMLIVMDKTTMLLVSGTGEVIEPDDGILAIGSGGNYALSAGRALKQYASEHLTAKQIAKASLEIAGDICVYTNHNIIVEEL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_PHLPP
Sequence: MGRYAREPDNATKSCKSRGSHLRVHFKNTHEAANAIKHMPLRRAQRFLKNVVEKKECVPFRRFNGGVGRCAQAKQWKTTQGRWPKKSAEFLLQLLRNAESNADYKGLDVDRLVIDHIQVNRAPCLRRRTYRAHGRINPYMSSPCHIEVILTEKEEVVAKATDEEPTKKKLSKKKLQRQKEKMMRSE
What are the official names of this protein?
60S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: ENV_HV2S2
Sequence: MCGRNQLFVASLLASACLIYCVQYVTVFYGVPVWRNASIPLFCATKNRDTWGTIQCLPDNDDYQEIALNVTEAFDAWNNTVTEQAVEDVWSLFETSIKPCVKLTPLCVAMRCNSTTAKNTTSTPTTTTTANTTIGENSSCIRTDNCTGLGEEEMVDCQFNMTGLERDKKKLYNETWYSKDVVCESKDTKKEKTCYMNHCNTSVITESCDKHYWDTMRFRYCAPPGFALLRCNDTNYSGFEPNCSKVVAATCTRMMETQTSTWFGFNGTRAENRTYIYWHGRDNRTIISLNKFYNLTILCKRPGNKTVVPITLMSGLVFHSQPINRRPRQAWCWFKGEWKEAMKEVKLTLAKHPRYKGTNDTEKIRFIAPGERSDPEVAYMWTNCRGEFLYCNMTWFLNWVENRTNQTQHNYVPCHIKQIINTWHKVGKNVYLPPREGQLTCNSTVTSIIANIDGGENQTNITFSAEVAELYRLELGDYKLIEVTPIGFAPTSIKRYSSAPVRNKRGVFVLGFLGFLTTAGAAMGAASLTLSAQSRTSLAGIVQQQQQLLDVVKRQQEMLRLTVWGTKNLQARVTAIEKYLKDQAQLNSWGCAFRQVCHTTVPWVNDTLTPDWNNITWQEWEQRIRNLEANISESLEQAQIQQEKNMYELQKLNSWDVFSNWFDLTSWIKYIQYGVYIVVGIIVLRMVIYVVQMLSRLRKGYRPVFSSPPAYS
What is the function of this protein?
The gp120-gp41 heterodimer allows rapid transcytosis of the virus through CD4 negative cells such as simple epithelial monolayers of the intestinal, rectal and endocervical epithelial barriers.  Both gp120 and gp41 specifically recognize glycosphingolipids galactosyl-ceramide (GalCer) or 3' sulfo-galactosyl-ceramide (GalS) present in the lipid rafts structures of epithelial cells.  Binding to these alternative receptors allows the rapid transcytosis of the virus through the epithelial cells.  This transcytotic vesicle-mediated transport of virions from the apical side to the basolateral side of the epithelial cells does not involve infection of the cells themselves (By similarity).
What are the official names of this protein?
Envelope glycoprotein gp160, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein gp41]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Surface protein gp120]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Host endosome membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag (By similarity).
Protein: SELO_GEMAT
Sequence: MQTLRFDNRFVDELPGDPDPRNQRRQVLGAAWSAVQPTPVTAPQLLAVAPDVAAMLGFSPEQTASPEFAAVFGGNALLEGMRPWAACYGGHQFGQWAGQLGDGRAISLGELVTTAGDRWELQLKGAGPTPYSRTADGRAVLRSSIREFLCSEAMHHLGVPTTRALSLVTTGDPVVRDVLYNGNPAPEPGAVVCRVAPSFVRFGNFEIFTARHDLTTLAQLVDFTIARDFPHIDGDVDARRAAWFREVCERTAHLMVHWMRVGFVHGVMNTDNMSILGLTIDYGPYGWLDNFDPQWTPNTTDAQGRRYRYAQQPAVAQWNLMRLADAIAPLFRDVTPLQAGLDHYGDVFLVAHEAMQAAKFGFVRQGPDEDALITEAFALMERVDIDFTRFFRALGDAPAALGDASAVTVLGDVFYDATLRDTHADALTAWLRRWHVAVGRQRPDAATRRTAMHAVNPWFVLRNYVAQQAIDAATAGDPSQVRLLLEVLRRPYDEQPEHAALVARRPEWARHKVGCSMLSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: EFTS_HALHL
Sequence: MSVSANLVKQLRERTGSGMMECKKALVEVDGDLEAAAELMRKKGLAKADKKADRVAAEGRVVAARSEDGKSGVLVEVNSETDFVGNGDEFRAFAESVAQRALDSKVEDLDSLLASEVDGKSVETLRQEMVAQLGENIEVRRFIRYAGDHQVAQYLHGARIGVMVEVQGGDEQLGRDLAMHIAASSPVCVSPDDVPADQLSSEKEVLLAQARESGKPEEIVEKMVEGRLKKHLSEITLLGQPFVKDPDQTVGDLLKAKGAEVTRFARYEVGEGKEKKDESFADEVMAQVRDS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTX25_ARATH
Sequence: MSGGGGEMEERLLNGSETEQRRESLYLRKKIWSEVRKMWRIALPSTLFRVMSFGCVVVAQAFIGHSSETGLAAYALLQSTFIRFIYGIMAGMSSATETLCGQAYGAEQYHMMGIYLQRSWIVDTFIATLFVPFIVLAGPILRLLGQNVVISETVDEIYPWVIPYLYSIVFTMTMQMYLQAQMKNAIIGILSTLALVLDIAATWWCVSVMGMGIHGALLGLNISSWSVAIAEFVYVFGGWCPHTWTGFSTAAFLDLIPMLKLSISSGFMLCLEYWYMSIIVLMSGYAKDANIAISAFSICQYIYSWEMNICFGLMGAACVRVANELGKGDADAVRFSIKVVLVVSAVIGVICSALCLAFGGQISYLFSDSQAVSDAVADLSIVLSISILFNIIQPILSGVAIGAGMQSMVALVNLASYYAIGVPLGVLLVYVFNFGIKGLWSGMLAGVGIQTLILCYVIYKTDWELEVKKTNERMKTWTLNLPAVQSTTISTRDEERK
What are the official names of this protein?
Protein DETOXIFICATION 25, AtDTX25, Multidrug and toxic compound extrusion protein 25, MATE protein 25.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RPOZ_CUPPJ
Sequence: MARITVEDCLKHIPNRFELALAATYRARQLVQGHTPKVEAKDKPTVVALREIASGQVGIEMLKKVPT
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RL20_BARHE
Sequence: MARVKRGVTAHAKHKKVLKQAEGFYGRRKNTIRAAKAAVDRSKQYAYRDRKNRKRTFRALWIQRINAAVRAEGLTYGRFIDGLSKAGIEIDRKVLSDIAIHESAAFSALVASAKKALEYLKDTTPNAFEGAVK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: SPN4_SCHPO
Sequence: MNEEETNFVGIADLPNQRHKIVSRNGVAFTLMLCGESGLGKTTFCNTLFSTTIKSHMGPEKVRAKHAEKTVEIEITKAELEEKNFHLRLTVIDTPGFGDFINNSGCWESVVEFIEDQHESYMRQDQQPDRRKIIDMRIHACLYFLRPVRNGVRPMDLEAMKHISKRVNLIPVIAKADMYTRRDLALYKTRISQVLEYHQVNVYKPNMDEGDPVFHRQIQGIINCMPFAIVGSEDDIRTPDGRVVKGREYPWGIVEIENEEHCDFKQLRNILIRSCMLDLIQTTEEKLYEQYRQEQMKVRQYGEPKLRTIDNAKFKEEEENLRKRFTEQVRVEETRFRQWEQRLIAERDSLNKDLEAQHVQIKQIELEIERLKAATSSRKR
What is the function of this protein?
Plays a role in the cell cycle.  Involved in a late stage of septum formation leading to the separation of the daughter cells.
What are the official names of this protein?
Septin homolog spn4.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Note=Localizes to the medial ring at the cell cortex of dividing cells.
Protein: G6PI_SHEPC
Sequence: MTLLTQSSTWQALSAHTQNLPHMRELFATDAARFKNMSLSACGLFLDYSKNRATAETLELLFSLAKDSQLEAKIKAMFAGEIINTTEKRAVLHTALRSKASQSIIAEGQDIVLEVQQTLSKMQEFVETVTSGQWKGYTGKAITDIVSIGIGGSFLGPKVVSQALRPYWNQGLNCHFVANVDGTSISEKLKLLDSETTLFIMSSKSFGTQETLTNTLTAKAWFLAKGGLQSDVAKHFVAVTSNVTKATEFGIDANNIFPMWDWVGGRYSLWSAIGLPIALLVGMDNFRALLNGAHQMDEHFASAPLAENMPVIMGLLSLWYGNFFNAQSHVVLTYDHYLRGLPAYFQQLDMESNGKSVTLDGTDVDYSTGPVIWGGEGTNGQHAYHQLIHQGTALIPADFIMPLQSHNPIGVHHDQLASNCFGQTQALMQGRTFEEALAELANSSLTDEEKQLIAKHKVMPGNKPSNTLLMNKLTPETLGALIALYEHRTFVQGAIWDINSFDQWGVELGKNLGNDVLARISAEQDSSALDASSNGLINLYRQGAI
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GP151_RAT
Sequence: MGKATLAVFADSDSSNMNESFAHLHFAGGYLPSDSKGWRTIIPSLLAAVCLVGFVGNLCVIGLLLHGVWKRKPSMIHSLILNLSLADISLLLFSAPVRATAYVKGVWDLGWFVCKSSDWFTHMCMAAKSLTFVVVAKVCFMYASDPAKPVGTHNCTIWSLLGAIWVVASLLPLPEWFFSTTRHHAGVEMCLVDVPAVAAEFMSLFGKLYPLLVFCLPLLLAGFYFWRAYNQCKIRCAKTQNLRNQMRSKQLTVMLLSTAVTSALLWLPEWIAWLWVWHLKAGGPMPPQGFIALSQVLMFSISTVNPLIFLMMSEEFKAGLKGIWKWMITRKPVVTSEVQEVPAGNIETLPGKAPSPETQTCIPDTDRCGSPDSSKETTDKVMVPILPDVEQFWHERDVGPSAQDNDPIPWEHEGQETKGCN
What is the function of this protein?
Orphan receptor.
What are the official names of this protein?
Probable G-protein coupled receptor 151, GPCR-2037.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFTS_XANOR
Sequence: MEITASLVKELRERTGAGMMECKKALVENAGDIDAAAEWLRKSGLAKADKKADRVAAEGRIATAQAGGKAVLVEVNSETDFVAKDENFLAFTEVVANAALNSDAADAEALKSVKLDSGETIEERRAAVIAKVGENLQVRRLVRIDSANNVAAYVHGGRIGVLVELKGGDIELARGIAMHIAAMNPPHVKASDVPAEFVAKEKEIELAKMSEKDKAKPADILEKIISGKISKIVNEVTLYGQPYVLNTDQTVEQAVKAAGAEVIRFQRLAVGEGIEKVVEDYAAEVMKQAGLA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.