PharMolix/UniProtQA huggingface dataset:
Protein: PTPA1_EMENI
Sequence: MDTSQVRILPKLDISAGHNFTKPSKRINESQDVAEFLSSKAYVDLMTFLLQLNRSLFPTKLPDGRVLTWELNSEAVEYSAPVRQLQQLLSKLEAILDEAPPDTGPRRFGNISFRRWYEMVESRAASLLEECLSKEILQMPSSDPGAPTAEVELLAYFLGSWGSPQRLDYGTGHELSFLAFLAGIWKLHGFPENSPGVEERAIVLGVIQPYLELVRTIIKRYTLEPAGSHGVWGLDDHSFIPYIFGSAQLAPAISESDRIPEEGSLSDAPAPGGVTKANVVERERKHNLYFSAIGFIYDVKRGPFWEHSPMLYDISGIQAGWAKINKGMIKMYNAEVLSKFPVVQHFPFGSLFSWERDPNAPSPAADAHIAATTRRTDEASTSSYLYSPKYIKATSWSYGSYKGALGNISTRWTGSPWRFYVCRPYANESSVG
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase.  Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A activator 1, Peptidyl-prolyl cis-trans isomerase PTPA-1, PPIase PTPA-1, Rotamase PTPA-1, Phosphotyrosyl phosphatase activator 1.
What is the protein family that this protein belongs to?
Belongs to the PTPA-type PPIase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HLDE_CAMJE
Sequence: MLEFLSQQKPKILIIGDFMVDNYTWCDCSRISPEAPVLIAKTLKEDKRLGGAANVYANLKSLGADVFALGVVGDDESGKFLQENLKGEFLIQKGRKTPFKNRIMAHNQQVLRLDEEDISEILLENELIALFDEKIKDFKAVVLSDYAKGVLTPKVCKAVIEKAKVLNIPVLVDPKGSDFNKYSGATLLTPNKKEALEALKFENLEGENLEKGIKKLKEDFSLRYSIITLSEAGIALFDEGLKIAPAKALEVYDVTGAGDSVIAVLAFCLANEIEIFKACELANEAAAVVVSKIGSVSVSFDEIKSFKRVDFEKKIKSKEELLVLLKQNNKKIVFTNGCFDIVHFGHIKYLDKAKRLGDVLIVGLNSDASVKRLKGESRPVNSEFQRACMLAAFYFVDFVVIFDEDTPLELISFLKPDILVKGADYKDKLVVGADIVSRVELIDFEEGFSTSKIIEKIKDKK
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: FAEB_MYCTT
Sequence: MLVRSFLGFAVLAATCLAASLQEVTEFGDNPTNIQMYIYVPDQLDTNPPVIVALHPCGGSAQQWFSGTQLPSYADDNGFILIYPSTPHMSNCWDIQNPDTLTHGQGGDALGIVSMVNYTLDKHSGDSSRVYAMGFSSGGMMTNQLAGSYPDVFEAGAVYSGVAFGCAAGAESATPFSPNQTCAQGLQKTAQEWGDFVRNAYAGYTGRRPRMQIFHGLEDTLVRPQCAEEALKQWSNVLGVELTQEVSGVPSPGWTQKIYGDGTQLQGFFGQGIGHQSTVNEQQLLQWFGLI
What is the function of this protein?
Feruloyl esterase which acts in synergy with xylanases in degradation of plant cell walls.  Hydrolyzes the ester linkage of hydroxycinnamic acids (ferulic acid (FA) and p-coumaric acid) and diferulates present in plant cell walls.  Is active on substrates containing ferulic acid ester linked to the C-5 and C-2 linkages of arabinofuranose, while it was found capable of de-esterifying acetylated glucuronoxylans.  Efficiently releases ferulic acid (FA) from destarched wheat bran when incubated with an M3 xylanase.
What are the official names of this protein?
Feruloyl esterase B, Cinnamoyl esterase, Ferulic acid esterase B, FAEB.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate esterase 1 (CE1) family. Feruloyl esterase type B subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GATC_ACIF5
Sequence: MAFDQDTVRRTAHLARIALPQAEIPAVADQLERIMGLVEELRAIETTDVPIMAHPLDLDQPLRPDMVVHQDQREVLMASAPAAEHGLFLVPKVIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: MINC_HELPJ
Sequence: MLKTNQKNVHAFEIEKQEPEAVMEFLEKNHALLQYFLIIFKYDIESEVKAVLHKHQLLFLETNRALNGRYIKTTEKDANLLKQNSPNAIEPKTTIYERNIRSGEEIYSTNHLIFLGNIHNGAKIISEGSVSVYGVCEGAIVCFGEYLILKEVKSAQIVFQNKILSLKEVERLLVNKNIKIITKNDDILDIKEVL
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization (By similarity).
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: YVFB_VACCC
Sequence: MDTASVIIDLTVSSLGGYNKCLNIKHAKSQCRPSSLLISSLENVSPGIRPRFLSQNMEANDPEKKIPSTAAKAISLSP
What are the official names of this protein?
Uncharacterized 8.3 kDa protein.
Protein: SYC1L_MOUSE
Sequence: MAAELEPLMAEWLGAEKAEDTRGQAASLNTMEDLLETVKKLQKEGSLEPQIEDLIHRINELQQGPAKKRSSEELGEAQALQEAMHRELDSLNEERVHLEEVLRKKQEAVSILKKHPQERDSDTPHLDAQQLEERLADLARQHKDLWEFHVLQQRLAQEISTMEHRKDQLLAERTLLRARLEKVEQRLQEARETWDSPGNCGLKTELEELEGQSQRSPEAQNDKGEASQEEQHHLETSEELPRTGTLC
What is the function of this protein?
May be involved in meiosis.  Isoform 1 may be involved in meiosis during spermatogenesis while isoform 2 is probably related to a later stage of meiosis, in the development stage of secondary spermatocytes and spermatids.
What are the official names of this protein?
Synaptonemal complex central element protein 1-like, Meiosis-related protein.
What is the protein family that this protein belongs to?
Belongs to the SYCE family.
Protein: HLD_STAAM
Sequence: MAQDIISTIGDLVKWIIDTVNKFTKK
What is the function of this protein?
Lyses erythrocytes and many other mammalian cells.
What are the official names of this protein?
Delta-hemolysin, Delta-lysin, Delta-toxin.
What is the protein family that this protein belongs to?
Belongs to the delta-lysin family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane. Note=In infected cells, it is found in the membrane.
Protein: PPTA_SHISS
Sequence: MPHIDIKCFPRELDEQQKAALAADITDVIIRHLNSKDSSISIALQQIQPESWQAIWDAEIEPQMEALIKKPGYSM
What are the official names of this protein?
Tautomerase PptA.
What is the protein family that this protein belongs to?
Belongs to the 4-oxalocrotonate tautomerase family. PptA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_STRZP
Sequence: MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQGFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATFLVRGLRNAADLQYEASFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEKKD
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_LEPBL
Sequence: MKFNFITLFPEKIQSYFSEGLQQKAIESGIFSINTIQLRDFSGNKHNRVDDTIYGGGPGMLLRVEPIHKALLSLGENKGIVILTSPSGIPFHQGIANKLKETGKPLTFISGYYEGVDHRVAEHLVDMEMSLGNYVISAGDLASICIADAVSRLLPGFLGAGESLLDESHNYPDVLEYPQFTKPSEYNGWKVPEVLLSGNHASILAWREQNRKKIDPDQERKL
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3B_SCHPO
Sequence: MSEILIEEIKDQIVVKDEEIDVSELEVKLNVTKPVGYDTVVVIEGAPVVEEAKQQDFFRFLSSKVLAKIGKVKENGFYMPFEEKNGKKMSLGLVFADFENVDGADLCVQELDGKQILKNHTFVVRKLNQLEKAFSTPDEFSFEEREFKEREHLRSWLTDYYGRDQFISYYGNRVSVNWNRKSDVPEQIVDRENWTETYVQWSPMGTYLVSLHLRGIQLWGGESWGMCARFLHPYVKFVDFSPNEKYLVSWSYEPVRLPPIGHPARETMPFTDDDEGKHCFVWDIASGRILRSFKIPPQPEGSKDGKKVIWPIFKWSADDKYLARVTVGQSISVYETPSLALVDKKTIKIDGVQNFEWCPVSDALGRDSKEQLLAYWTPEITNQPARVALISIPSKSTIRTKNLFNVSDCKLYWQSNGDYLCVKVDRHTKTKKSTFSNLEIFRIREKNIPVEVVDLKDVVLNFAWEPKSDRFAIISANDQVLNSTNVKTNLSFYGFEQKKNTPSTFRHIITFDKKTCNSLFMAPKGRFMVAATLGSSTQYDLEFYDLDFDTEKKEPDALANVQQIGSAEHFGMTELEWDPSGRYVTTSSTIWRHKLENGYRLCDFRGTLLREEMIGEFKQFIWRPRPPSPLTKEDMKKIRKKLKDYNRLFDEEDIAEQSSANRELAARRRQLISEWQKYRDEVIARVAEERAITGQPAITVPAEEEEIIQETVEEVISEEIEPVED
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit B, eIF3b, Eukaryotic translation initiation factor 3 90 kDa subunit homolog, eIF3 p90, Translation initiation factor eIF3 p90 subunit homolog, spPrt1.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit B family.
Protein: Y313_MYCTO
Sequence: MGDYGPFGFDPDEFDRVIREGSEGLRDAFERIGRFLSSSGAGTGWSAIFEDLSRRSRPAPETAGEAGDGVWAIYTVDADGGARVEQVYATELDALRANKDNTDPKRKVRFLPYGIAVSVLDDPVDEAQ
What are the official names of this protein?
Uncharacterized protein MT0327.
Protein: KEA2_ARATH
Sequence: MDFASSVQRQSMFHGGADFASYCLPNRMISAKLCPKGLGGTRFWDPMIDSKVRSAIRSKRNVSYRSSLTLNADFNGRFYGHLLPAKPQNVPLGFRLLCQSSDSVGDLVGNDRNLEFAEGSDDREVTFSKEEKDTREQDSAPSLEELRDLLNKATKELEVASLNSTMFEEKAQRISEVAIALKDEAASAWNDVNQTLNVVQEAVDEESVAKEAVQKATMALSLAEARLQVALESLEAEGYNTSEESEVRDGVKDKEEALLSAKADIKECQENLASCEEQLRRLQVKKDELQKEVDRLNEAAERAQISALKAEEDVANIMVLAEQAVAFELEATQRVNDAEIALQRAEKTLFGSQTQETTQGKVLDGKNTIVGEDEVLSEIVDVSHQAERDLVVVGVSSDVGTQSYESDNENGKPTADFAKEAEGEAEKSKNVVLTKKQEVQKDLPRESSSHNGTKTSLKKSSRFFPASFFSSNGDGTATVFESLVESAKQQWPKLILGFTLLGAGVAIYSNGVGRNNQLPQQPNIVSTSAEDVSSSTKPLIRQMQKLPKRIKKLLEMFPQQEVNEEEASLLDVLWLLLASVIFVPLFQKIPGGSPVLGYLAAGILIGPYGLSIIRNVHGTKAIAEFGVVFLLFNIGLELSVERLSSMKKYVFGLGSAQVLVTAAVIGLITHYVAGQAGPAAIVIGNGLALSSTAVVLQVLQERGESTSRHGRATFSVLLFQDLAVVVLLILIPLISPNSSKGGIGFQAIAEALGLAAIKAAVAITGIIAGGRLLLRPIYKQIAENRNAEIFSANTLLVILGTSLLTARAGLSMALGAFLAGLLLAETEFSLQVESDIAPYRGLLLGLFFMTVGMSIDPKLLLANFPLIMGTLGLLLVGKTILVVIIGKLFGISIISAVRVGLLLAPGGEFAFVAFGEAVNQGIMTPQLSSLLFLVVGISMALTPWLAAGGQLIASRFELQDVRSLLPVESETDDLQGHIIICGFGRIGQIIAQLLSERLIPFVALDVSSDRVAIGRSLDLPVYFGDAGSREVLHKIGADRACAAAIALDTPGANYRCVWALSKYFPNVKTFVRAHDVDHGLNLEKAGATAVVPETLEPSLQLAAAVLAQAKLPTSEIATTINEFRSRHLSELAELCEASGSSLGYGFSRSTSKPKPPSPSETSDDNQIIEGTLAI
What is the function of this protein?
Electroneutral K(+)/H(+) efflux antiporter modulating monovalent cation and pH homeostasis in plastids, especially during plastid division and thylakoid membrane formation (PubMed:22551943, PubMed:24278440, PubMed:33111995, PubMed:27443603, PubMed:31296940).  Transports K(+) and Cs(+) preferentially relative to Na(+) or Li(+) (PubMed:22551943).  May function in osmotic adjustment (PubMed:24278440).  Collaboratively with KEA1, adjusts alkaline stromal pH upon light to dark transitions in plastids (PubMed:33111995).  Together with KEA1, critical for chloroplast development, including chloroplast RNA-metabolism (e. g.  rRNA maturation, polysome loading and RNA-protein interactions) and plastid gene expression (PGE), ion homeostasis, and photosynthesis (PubMed:34235544, PubMed:27443603).  Contributes, during early seedling development, to the regulation of photosynthesis and abscisic acid- (ABA-) mediated primary root growth in a sucrose-dependent manner (PubMed:35193734).  Involved in the regulation of reactive oxygen and nitrogen species (ROS and RNS) metabolism (PubMed:33485149).  Required in roots for rapid hyperosmotic-induced Ca(2+) responses and for osmo-sensory potentiation in hyperosmotic conditions (PubMed:27528686).  May counteract resilience to drought and salt stress, involving photorespiratory pathway and stomata closure (PubMed:33485149, PubMed:34235544).
What are the official names of this protein?
K(+) efflux antiporter 2, chloroplastic, AtKEA2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KEA (TC 2.A.37.1) subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: PTH_THIDA
Sequence: MTAPSLAPPRLIVGLGNPGRDYEETRHNAGFWFCARLAQAWGAALAHESRFHGIVGRHGTRWMLLPQTFMNRSGQAVGALARFHRIAPAEILVVHDELDIPPGQLRLKFGGGMGGHNGLKDITAHLGTQDYWRLRIGIGHPGDRSEVVNYVLKPPRREEQADIDAAIERALGLLPLIEKGEWNAATQRANSKPASPKSQETP
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLC3A_BOVIN
Sequence: MAKNGLVIYILVITLLLDQTSCHASKFKARKHSKRRVKEKDGDLKTQVEKLWREVNALKEMQALQTVCLRGTKFHKKCYLAAEGLKHFHEANEDCISKGGTLVVPRSADEINALRDYGKRSLPGVNDFWLGINDMVAEGKFVDINGLAISFLNWDQAQPNGGKRENCALFSQSAQGKWSDEACHSSKRYICEFTIPQ
What is the function of this protein?
Promotes cell adhesion to laminin and fibronectin.
What are the official names of this protein?
C-type lectin domain family 3 member A, C-type lectin superfamily member 1, Cartilage-derived C-type lectin.
What are the subcellular locations of this protein?
Secreted.
Protein: HYPA_AZOCH
Sequence: MHEMSIAEGIVQLLEEQAAAQRFERVKAVWLEIGPLAAVEVESLRFCFEAVTRGSLAEGARLEIVELPGRAWCLGCNASVAIRQRYDACPQCGSYRLQVTQGDELRVKELEVE
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA, Protein HupA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: HTPX_STRSV
Sequence: MLFDQIASNKRRTWLLLIAFFGLLALLGAAIGYLWLRSAVGGVLLALIIGAIYAGVMIFQSTEVVMAMNGAREVSEQEAPELYHIVQDMAMVAQIPMPRVYIVEDPSPNAFATGSKPENAAVAATTGILQIMNREELEGVIGHEVSHIRNYDIRISTIAVALASAITMLSSLAGRMMWFGGGRRSSNDRDNDSGLGIILLIVSLIAIVLAPLAATLVQLAISRQREFLADASSVELTRNPQGMINALLKLDRSEPMEHHVDDASAALYISDPKKEGGLKKLFYTHPPISERVERLRHM
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PDE6B_HUMAN
Sequence: MSLSEEQARSFLDQNPDFARQYFGKKLSPENVAAACEDGCPPDCDSLRDLCQVEESTALLELVQDMQESINMERVVFKVLRRLCTLLQADRCSLFMYRQRNGVAELATRLFSVQPDSVLEDCLVPPDSEIVFPLDIGVVGHVAQTKKMVNVEDVAECPHFSSFADELTDYKTKNMLATPIMNGKDVVAVIMAVNKLNGPFFTSEDEDVFLKYLNFATLYLKIYHLSYLHNCETRRGQVLLWSANKVFEELTDIERQFHKAFYTVRAYLNCERYSVGLLDMTKEKEFFDVWSVLMGESQPYSGPRTPDGREIVFYKVIDYVLHGKEEIKVIPTPSADHWALASGLPSYVAESGFICNIMNASADEMFKFQEGALDDSGWLIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEQDEVLMESLTQFLGWSVMNTDTYDKMNKLENRKDIAQDMVLYHVKCDRDEIQLILPTRARLGKEPADCDEDELGEILKEELPGPTTFDIYEFHFSDLECTELDLVKCGIQMYYELGVVRKFQIPQEVLVRFLFSISKGYRRITYHNWRHGFNVAQTMFTLLMTGKLKSYYTDLEAFAMVTAGLCHDIDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKFLLSEETLNIYQNLNRRQHEHVIHLMDIAIIATDLALYFKKRAMFQKIVDESKNYQDKKSWVEYLSLETTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPMMDRNKAAELPKLQVGFIDFVCTFVYKEFSRFHEEILPMFDRLQNNRKEWKALADEYEAKVKALEEKEEEERVAAKKVGTEICNGGPAPKSSTCCIL
What is the function of this protein?
Rod-specific cGMP phosphodiesterase that catalyzes the hydrolysis of 3',5'-cyclic GMP (PubMed:20940301).  Necessary for the formation of a functional phosphodiesterase holoenzyme (By similarity).  Involved in retinal circadian rhythm photoentrainment via modulation of UVA and orange light-induced phase-shift of the retina clock (By similarity).  May participate in processes of transmission and amplification of the visual signal (PubMed:8394174).
What are the official names of this protein?
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta, GMP-PDE beta.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor. Cell projection, cilium, photoreceptor outer segment.
Protein: MNHA2_STAAU
Sequence: MSLVYLLIAILVIMAMILLMSKRRALAKYAGYIALVAPVISSIYFLIQIPSVAKLQYLSTSIPWIKTLDINLDLRLDGLSLMFSLIISLIGIAVFFYATQYLSSRKDNLPRFYFYLTLFMFSMIGIVLSDNTILMYIFWELTSVSSFLLISYWYNNGDSQFGAIQSFMITVFGGLALLVGFIMLYIMTGTNNITEILGQADHIKNHGLFIPMIFMFLLGAFTKSAQFPFHIWLPRAMAAPTPVSAYLHSATMVKAGIFLLLRFTPLLGLSNMYVYIVTFVGLITMLFGSITALKQWDLKGILAYSTISQLGMIMAMVGIGGGYAQHQQDAIASIYVFVLFGALFHLMNHAIFKCALFMGVGILDHEAGSRDIRILSGMRQLFPKMNLVMTIAALSMAGVPFLNGFLSKEMFLDALTQTGQLSQFSLISMIAIVFVGVIASVFTFTYALYMVKEVFWTKYDSKVFTKKNIHEPWLFSLPSLILMVLVPVIFFVPNIFGKGIIVLALRAVSGGNHQIDQLAPHVSQWHGFNIPLLLTIIIILLGSVLAIKVDWKKVFTGKIRQISVSKSYEMVYRHFEKFATKRFKRVMQDRLNQYIIMTLGIFMIIIGYGYIRIGLPKVHQLHVSEFGALEIILAIVTVTIGISLIFIRQRLTMVILNGVIGFVVTLFFIAMKAPDLALTQLVVETITTILFIVSFSRLPNVPRSNANKKREIIKISVSLLMALIVVSLIFITQQTDGLSSISDFYLKADKLTGGKNIVNAILGDFRALDTLFEGLVLIITGLGIYTLLNYQDRRGQDERE
What is the function of this protein?
Expression of the mnh2 operon in E. coli is not able to catalyze Na(+)Li(+)/H(+) antiport.  It does however confer higher growth rates than the control strain at up to pH 9. 5.  The operon may encode an NADH-ubiquinone oxidoreductase.
What are the official names of this protein?
Putative antiporter subunit mnhA2, Mrp complex subunit A2, Putative NADH-ubiquinone oxidoreductase subunit mnhA2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COF_ECOBW
Sequence: MARLAAFDMDGTLLMPDHHLGEKTLSTLARLRERDITLTFATGRHALEMQHILGALSLDAYLITGNGTRVHSLEGELLHRDDLPADVAELVLYQQWDTRASMHIFNDDGWFTGKEIPALLQAFVYSGFRYQIIDVKKMPLGSVTKICFCGDHDDLTRLQIQLYEALGERAHLCFSATDCLEVLPVGCNKGAALTVLTQHLGLSLRDCMAFGDAMNDREMLVSVGSGFIMGNAMPQLRAELPHLPVIGHCRNQAVSHYLTHWLDYPHLPYSPE
What is the function of this protein?
Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).
What are the official names of this protein?
HMP-PP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family.
Protein: HSLV_PHOLL
Sequence: MTTIVSVRRNGQVVIGGDGQATMGNTVMKGNVRKVRRLYNDKVIAGFAGGTADAFTLFELFERKLEMHQGHLTKAAVELAKDWRTDRMLRKLEALLAVADENTSLIITGNGDVIQPENDLIAIGSGGPFAQSAARAMLENTDLGARQIAEKALTIAGDICIYTNHNHNFEELPSKA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSHA_LISMO
Sequence: MTKFSEFGLDEKIVKSVNRMGFEEATPIQEKTIPLGLEGKDLIGQAQTGTGKTAAFGLPMIHKIDQKSNNVQALIIAPTRELAIQVSEELYKLSYDKHVRVLAVYGGSDISRQIRSLKKNPQIVVGTPGRILDHINRRTLKLDHVETLVLDEADEMLNMGFIDDIETILKEVPAERQTLLFSATMPDPIRRIGERFMHSPELIRIKAKEMTALLIEQFFVKVHEKEKFDVLSRLLDVQAPELAIVFGRTKRRVDELSRALDMRGYVAEGIHGDLTQAKRMSVLRKFKEGKIDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAGKEGMAITFVQPREMGYLRIVEETTKKRMQPLQAPTWDEAFAGQLRVATEKIQEAITEENLADYKTFANELLEKYDATDIAAAMLKMLAKEPDKTPVHITEERPLPSRGGGGYKGKNGKGGKGGGYRGGSGKGGSYRDRNNSGKGRRSGGGSGGGSGSGGGGNRDRRGGGEQRSGGNKGNYSQKSK
What is the function of this protein?
DEAD-box RNA helicase possibly involved in RNA degradation.  Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity (By similarity).  Involved in cold tolerance, motility and alcohol tolerance.
What are the official names of this protein?
ATP-dependent RNA helicase CshA.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. CshA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPD_STAA3
Sequence: MALSTFKREHIKKNLRNDEYDLVIIGGGITGAGIALDASERGMKVALVEMQDFAQGTSSRSTKLVHGGLRYLKQFQIGVVAETGKERAIVYENGPHVTTPEWMLLPMHKGGTFGKFSTSIGLGMYDRLAGVKKSERKKMLSKKETLAKEPLVKKEGLKGGGYYVEYRTDDARLTIEVMKRAAEKGAEIINYTKSEHFTYDKNQQVNGVKVIDKLTNENYTIKAKKVVNAAGPWVDDVRSGDYARNNKKLRLTKGVHVVIDQSKFPLGQAVYFDTEKDGRMIFAIPREGKAYVGTTDTFYDNIKSSPLTTQEDRDYLIDAINYMFPSVNVTDEDIESTWAGIRPLIYEEGKDPSEISRKDEIWEGKSGLLTIAGGKLTGYRHMAQDIVDLVSKRLKKDYGLTFSPCNTKGLAISGGDVGGSKNFDAFVEQKVDVAKGFGIDEDVARRLASKYGSNVDELFNIAQTSQYHDSKLPLEIYVELVYSIQQEMVYKPNDFLVRRSGKMYFNIKDVLDYKDAVIDIMADMLDYSPAQIEAYTEEVEQAIKEAQHGNNQPAVKE
What are the official names of this protein?
Aerobic glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_RICFE
Sequence: MFILHATILTVFPEMFPGTLGYSLAGQALHKNIWSYDVINIRDFGLTKHKNVDDEAYGGGDGLIMRPDVLGSSIDHALSLNPNAEIYYPSPRGRVFTQSFAKEMLKNKNLIFLCGRYEGIDERVIEEYNVKEISVGDYILSGGEIPTLTILDCLIRLLPGVLMNQNTLSSESFEEVGEFKGGLECGLYTRPEIWRDRAVPSVLLSGNHRLINEWKKEQSRIITKLRRPELLKDL
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSD_GEODF
Sequence: MSKTLTHLQQLEAESIHIIREVVAEFANPVMLYSIGKDSAVMLHLARKAFYPAPPPFPLLHVDTTWKFREMIQFRDRMAAECGLDLIVHVNEEGVKNGISPFTHGSALYTDVMKTEGLKQALDKYKFDAAFGGARRDEEKSRAKERIFSFRSANHRWDPKNQRPELWNLYNTRIKPGESIRVFPLSNWTELDVWQYIHLENIPIVPLYYAAVRPVVERDGMLIMVDDDRLELKPGETVQHKSVRFRTLGCYPLTGAVESTADTLPQIIQEMLLTRTSERQGRLIDHDQAGSMEKKKQEGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: DER_CHLL2
Sequence: MKPLIALVGRPNVGKSTLFNRILRQKSAIVDSTPGVTRDRHIMPGEWQGKQFLLMDTGGYCAANDVISSSMIEQTLTAIRDADCVIFLTDVRSGLTYDDLEISKLLQRTFQNKQIFFAVNKVESPQLTIDAESFVSTGFTRPYFLSAKDGSGVADMLDDILESLPESEHTDDDEDTSVKLAVVGRPNVGKSSFVNALLGTNRHIVSDIPGTTRDAIDSRFIRKQQEYVLIDTAGLRKRTKIDAGVEFYSSLRTEKAIERCQVAVVLLDARAGLEKQDLKIINMAEERKKGVLLLVNKWDLIEKDSKTSKIYEDDLRSHMGNLSWIPVLFISALTKKNLYRAIDTAEEISRNRSRKISTSSLNRFLEEALSAVHPSTKSGKELKIKYMTQIDSHWPVFAFFCNNPELVQSNFRKFLEKKLREQFQLDGVPISLRFMEK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.