PharMolix/UniProtQA huggingface dataset:
Protein: PA2HE_TRIST
Sequence: MRTLWIMAVLLLGVEGSVIELGKMIFQETGKNPATSYGLYGCNCGPGGRRKPKDATDRCCYVHKCCYKKLTDCDPIKDRYSYSWVNKAIVCGEDNPCLKEMCECDKAVAICFRENLDTYDKKKKINLKLFCKKTSEQC
What is the function of this protein?
Snake venom phospholipase A2 homolog that lacks catalytic activity (PubMed:12959640).  It shows myotoxic and weak anticoagulant activities and induces local edema a few hours after injection (5-10 ug) in the hind paw (PubMed:12959640).  A model of myotoxic mechanism has been proposed: an apo Lys49-PLA2 is activated by the entrance of a hydrophobic molecule (e. g.  fatty acid) at the hydrophobic channel of the protein leading to a reorientation of a monomer (By similarity).  This reorientation causes a transition between 'inactive' to 'active' states, causing alignment of C-terminal and membrane-docking sites (MDoS) side-by-side and putting the membrane-disruption sites (MDiS) in the same plane, exposed to solvent and in a symmetric position for both monomers (By similarity).  The MDoS region stabilizes the toxin on membrane by the interaction of charged residues with phospholipid head groups (By similarity).  Subsequently, the MDiS region destabilizes the membrane with penetration of hydrophobic residues (By similarity).  This insertion causes a disorganization of the membrane, allowing an uncontrolled influx of ions (i. e.  calcium and sodium), and eventually triggering irreversible intracellular alterations and cell death (By similarity).
What are the official names of this protein?
Basic phospholipase A2 homolog Ts-K49a, svPLA2 homolog.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. K49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y3808_PSEAE
Sequence: MSLKWTDVLEIAIQLDESKPEVDPRYVNFVDLRRWVVELPEFSDDPQRSGEKVLEAIQAAWIEERD
What are the official names of this protein?
Uncharacterized protein PA3808.
What is the protein family that this protein belongs to?
To E.coli YfhJ.
Protein: CH10_RICTY
Sequence: MSFKPLHDRIAIKPIENEEKTKGGIIIPDTAKEKPMQGEIVAVGNGVLNKNGEIYPLELKVGDKVLYGKWAGTEIEIKGEKLIVMKESDVFGIIN
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, 10 kDa heat shock protein, Chaperonin-10, Cpn10, HSP10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAMD1_HUMAN
Sequence: MAGPPALPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRRRHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAASARPSRSKRGGEERVLEKEEEEDDDEDEDEEDDVSEGSEVPESDRPAGAQHHQLNGERGPQSAKERVKEWTPCGPHQGQDEGRGPAPGSGTRQVFSMAAMNKEGGTASVATGPDSPSPVPLPPGKPALPGADGTPFGCPPGRKEKPSDPVEWTVMDVVEYFTEAGFPEQATAFQEQEIDGKSLLLMQRTDVLTGLSIRLGPALKIYEHHIKVLQQGHFEDDDPDGFLG
What is the function of this protein?
Unmethylated CpG islands (CGIs)-binding protein which localizes to H3K4me3-decorated CGIs, where it acts as a transcriptional repressor (PubMed:33980486).  Tethers L3MBTL3 to chromatin and interacts with the KDM1A histone demethylase complex to modulate H3K4me2 and H3K4me3 levels at CGIs (PubMed:33980486).  Plays a role in atherogenesis by binding with LDL on cell surface and promoting LDL oxidation which leads to the formation of foam cell (PubMed:16159594, PubMed:34006929).
What are the official names of this protein?
Sterile alpha motif domain-containing protein 1, SAM domain-containing protein 1, Atherin.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Secreted. Note=In atherosclerotic lesions, it is found in the extracellular compartment and in foam cells cytoplasm.
Protein: FOLD_YERP3
Sequence: MSAKIIDGKTIAQQVRNEVAAVVQQRLAAGKRAPGLAVVLVGENPASQIYVASKRKACEEVGFVSRSYDLPMATSEAELLALIDSLNEDTEIDGILIQLPLPNGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPKLRACTPRGIMTLLERYDIPTYGLNAVVVGASNIVGRPMSLELLLAGCTTTVTHRFTKNLRHHIENADLLVVAVGKPGFIPGEWIKPGAIVIDVGINRLESGKVVGDVAFDVAAERAGWITPVPGGVGPMTVATLIQNTLQACEEYHDISQN
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: GPMA_MYCMM
Sequence: MGDTGTLVLLRHGESDWNARNLFTGWVDVGLTEKGRAEAVRSGELLAEQDLLPDVLYTSLLRRAITTAHLALDSADRLWIPVRRSWRLNERHYGALQGLDKAETKARYGEEQFMAWRRSYDTPPPLIEKGSEFSQDADPRYANIDGGPLTECLADVVARFLPYFTDVIVGDLRAGKTVLIVAHGNSLRALVKHLDHMSDEDIVGLNIPTGIPLRYDLDERLQPVVPGGTYLDPEAAAAGAAAVASQGAAKA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: UN45B_XENTR
Sequence: MEDPVQLKEEGNKYFQSNEYGQAIQCYSKALKLITDKKMQAVLYRNRSACYLKQDNYVQAAADASKAIDVDASDIKALFRRCQALEKLGKLDQAYKDVQRCATLEPKNRTFLETLHRLGTNIQEKLHVQFSTDSRVHKMFEILLDKNSEKEKREKAANNLIVLGREDAGAEQIFQNNGVNLLMQLIESKDPEMILSAIRTLSGMCTGHRARATAIVHLVGINKICSIMAVDNEEIALAACNLLQNIVDSLTGEDKKAHGKQEALVLDTKKDLKIITTHLLDMLVSKKVSGHGRDQALNLLNKNIPRYDLKNKDNSKSLFVVDAGLKKILKVLGQVPELPNCLPLTPNTRLNASVLVNKLYDDLRCDPERDNFRIICEEYITGSFDPKDMEKNLHAIQTVSGILQGPFDLGNKLLSLQGVMEMMVALTGSENEVDQLVAVEALIHASTKLSRASFIITNGVSLLKDIYKKTKNEKIKIRALVGLCKLGSAGGTDYALRQFAEGSTDKLAKQCRKWLCNPSLDIQTRKWAVEGLAYLTLDADVKDEFVEDEQSLKAMFELSKTSDKTILYSVATTLVNCTNSYDVKEVIPEMVQLAKFSKQHVPEQHPKDKKDFVEKRVKRLLKADVISALSCMVKADNSILTDQTKEQLSRVFLALCEDPKDRGIIVAQGGGKAMIPLALEGTDVGKIKASHGLAKIAAVSNPDIAFPGERVYEVVRPLVSLLNTERDGIQNFEALLALTNLSGKNDKLRQKIIKEKALPEIENYMFENHEQIRQAATECMCNLALNKEVKERFMAEGNDRLKLIILLCGEEDEVKLQRAAAGTLAMLTGAEKKLCHKMTEVTTQWMEILQRLCLSEDLQVQHRGVVIAYNLINADKELAKKLVESEMLEILTVIGKQADVPNKQHIINAAREALVKCLDYGFIKTVS
What is the function of this protein?
Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain (By similarity).  Plays a role in sarcomere formation during muscle cell development.  Is necessary for normal early lens development.
What are the official names of this protein?
Protein unc-45 homolog B, Unc-45B.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, Z line. Cytoplasm, myofibril, sarcomere, A band. Cytoplasm, perinuclear region. Cytoplasm, cytosol. Note=Expressed at the Z line and in the perinuclear region of myofibrils. Translocates to the A band in response to stress conditions and fibril damage.
Protein: C3H67_ARATH
Sequence: MSKPEETSDPNPTGPDPSRSSSDEVTVTVADRAPSDLNHVSEELSDQLRNVGLDDSAKELSVPISVPQGNVETDSRALFGSDQKEEEEGSEKRMMMVYPVRPDSEDCSFYMRTGSCKYGSSCKFNHPVRRKLQIGRERVRERDEDVENPKLMECKYYFRTGGCKYGESCRFSHMKEHNSPASVPELNFLGLPIRPGEKECPFYMRNGSCKFGSDCKFNHPDPTAIGGVDSPLYRGNNGGSFSPKAPSQASSTSWSSTRHMNGTGTAPFIPSMFPHSRGVTPQASDWNGYQASSAYPPERSPLAPSSYQVNNSLAETSSFSQYQHQMSVEEFPERPDQPECTYYLKTGDCKFKYKCKYHHPKNRLPKQAAFSFNDKGLPLRPDQSMCTHYSRYGICKFGPACRFDHSIPPTFSPSSSQTVEARQVGANGNEDDSWH
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 67, AtC3H67, Zinc finger CCCH domain-containing protein ZFN-like 5.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y864_SHEHH
Sequence: MKQHLWPLFLEAVKRDVVPALGCTEPISVALAAAIAIDELGIKNQASNVKLDVKIDVAVSANLMKNGMGVGIPGTGMVGLPIAAAIGAIAGDRHAGLEVLKSIKDSDVQAAKLMLANELVTVGVADVANILYAKVTVYYQQQTASVTIADSHTKVIAIEKNGEQCLLESQAKTTNDNSCKANPFTEAKLQDIYDFAMQAPLDDIRFIMQAKTLNDALSIEGLSGNYGLKIGATLVKNQAKGLLSGGLLTEVLARTAGASDARMDGAMMPAMSNSGSGNQGIAATMPVVACAEFLKSSETQTIRALMLSHLTAIYIKSYQNKLSALCGATTASMGAAAGITYLLDGELEQISAAICSMIGDVSGIICDGAKASCAMKVSSSAGSAVKSALMAIDGIRVTGTEGIVADDVDQTICNLATLANGAMTQTDVQILEIMLHK
What are the official names of this protein?
UPF0597 protein Shal_0864.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: COX4_SCHPO
Sequence: MFMNSMLRVSRQRAAVRSTVSLYRGFVSASIRRNEQNVVKAAAQELANAKEPSDLIGPGGRDGEVPTDLEQATGLERYELLSELSGRDAFDMKPLDASRKGTLTDPIMVTSLDPYRHIGCTGSPSGSHNLIWMTVYKDKLRRCPECGSVYKLKFMGDPNAEHSH
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 4, mitochondrial, Cytochrome c oxidase polypeptide IV.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 5B family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: IF1A_METLZ
Sequence: MGRIENDNQDVSDDGSIIRVKLPNKRIREQFAQAELMLGSNHIRVRCSDGVTRLGRIKGKIKKRVWIREGDILIVVPWDFQDDKCDIIYRYTTPQVDWLRAHKYL
What is the function of this protein?
Seems to be required for maximal rate of protein biosynthesis.  Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
What are the official names of this protein?
Translation initiation factor 1A, aIF-1A.
What is the protein family that this protein belongs to?
Belongs to the eIF-1A family.
Protein: RUTA_ECOL6
Sequence: MQTSHYAAEKDMQDAAPRLTFTLRDEERLMMKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGSGKSDFKGDFFTMDDCRVSPQPSVPMKVICAGQSDAGMAFSARYADFNFCFGKGVNTPTAFAPTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQKDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVANVPGAEGVLLTFDDFLSGIETFGERIQPLMLCRAHLPALTQEVA
What is the function of this protein?
Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide.  The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN.  Requires the flavin reductase RutF to regenerate FMN in vivo.
What are the official names of this protein?
Pyrimidine monooxygenase RutA.
What is the protein family that this protein belongs to?
Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
Protein: COAD_METS4
Sequence: MNRTALYAGSFDPVTNGHVDVIRQACRLVPRLVIAIGVHPGKTPLFGAEERAELLREICAPLAAAEGAALDVVTFDDLAVSAARRVGASLFIRGLRDGTDLDYEMQLAGMNGAMAPEVQTVFLPASTGVRPITATLVRQIAAMGGDVRPFVPDLVAERLRARFAKP
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMI_CLOB1
Sequence: MSKKPVVLMILDGFGLTNKVDGNAVSAANKPNLDNILKKYPHTQLGASGMDVGLPEGQMGNSEVGHLNIGAGRIVYQALTKITKSISDGDFFENVALNKAIENVKKNNSTLHLLGLLSPGGVHSHIDHLKGLIKLAKEKDIKKVYIHAFLDGRDVAPSSAKEYIEDIENYMNEIGVGEIATISGRYYAMDRDKRWERVQLCYNAIVLGKGEEANSAVEGLEKSYRDNKTDEFVLPSVVLKEGKPKAKIENKDSVVFFNFRPDRARELTRAINDKVFDGFERETLDLTYVTVTEYDSTLENVEVAFPPEHLNNTLGEYVSKNGKKQLRIAETEKYAHVTFFFNGGVEEPNEGEDRVLIPSPKVATYDMQPEMNAYEVTDKLLERLDEDKYDMVILNFANPDMVGHTGVFEAAKKAIETVDECVGKIVNKVLEKDGTAFITADHGNSEEMIDYSTGKPMTAHTTNPVPFMYVSKNSKELREGGKLADIAPTMLQLMNLPKPSEMTGNSLIK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: RL9_STRPF
Sequence: MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATSQSIGELKGKQKAEEKAQAEILAEAQAVKAVLDEDKTRVQFQEKVGPDGRTFGSITAKKISEELQKQFGVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLAITEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: ISPH_ANAMM
Sequence: MEAVQQNHSVCRGYCGVMLRSRSGGFFRRGFMLGNVEVILARPRGFCAGVERAVRTLESVASRYAGTREVYALHEIVHNLHVVNSFKKMGVKFVSALHEVPEGAVLVFSAHGVSQQVKEESRRKGLTVVDATCPLVTKVHLEIQRYDKSGYQVILVGHKGHREVEGSMGQVSNPVVLVQNVQDVQSIKIPSAAKLAYVTQTTLSMDDTAEIISALKLRFPRIVGPDLRDICYATQNRQTAVKAMSQMVDVVLAIGSKNSSNSNRLLDLAKAQNARAYLIDSYRNIDLEWLIGARRIGITAGASAPEILVQEVIDYLGLHANLKVRTMDGVSENITFKLPELD
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: Y358_ROSDO
Sequence: MLVVISPAKRLDWAERDVPVTQPDFQEDAVRLSKTARNLTLGSLKSLMGLSDDLARLNRDRFNAFAEDPAPEATRPAALAFAGDTYQGLEATSLDENERAWAQDHLRILSGLYGVLRPLDAIQPYRLEMGSRLKTRRGSNLYEYWRDDLSKALNAQAQSVGTDVLINCASQEYFGAVAPKALKLRVITPAFMEDKNDGKGPKIVSFFAKKARGAMARFVIQNRLSDPDALTGFDTGGYAYQPELSTPDKPVFIRPYPAS
What are the official names of this protein?
UPF0246 protein RD1_0358.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: RSMH_FRATH
Sequence: MHYSVLLQESINDLNINPQGIYIDATFGRGGHSKAILNRLTTGRLIAFDKDLDAISYARENFQFSNFEIVHASFASIYDYCLQHSLLGKIDGIIMDLGVSSPQLDNAARGFSFTHNGPLDMRMDVSKGITASQALEELSVYDLSYIFKVYGEERFAKKIALRIKDYIQQNGSIRTTLELAELIRATIGKKEKKNPATRCFQALRIYVNNELKDLEALLENILAVIKSGGRIAAISFHSLEDRIVKQKFSALINPKQELNRITKMLPQDSSQIKLKWITKKSKANEDELNQNVRSRSAILRVVEKL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_HUMAN
Sequence: MAASKKAVLGPLVGAVDQGTSSTRFLVFNSKTAELLSHHQVEIKQEFPREGWVEQDPKEILHSVYECIEKTCEKLGQLNIDISNIKAIGVSNQRETTVVWDKITGEPLYNAVVWLDLRTQSTVESLSKRIPGNNNFVKSKTGLPLSTYFSAVKLRWLLDNVRKVQKAVEEKRALFGTIDSWLIWSLTGGVNGGVHCTDVTNASRTMLFNIHSLEWDKQLCEFFGIPMEILPNVRSSSEIYGLMKISHSVKAGALEGVPISGCLGDQSAALVGQMCFQIGQAKNTYGTGCFLLCNTGHKCVFSDHGLLTTVAYKLGRDKPVYYALEGSVAIAGAVIRWLRDNLGIIKTSEEIEKLAKEVGTSYGCYFVPAFSGLYAPYWEPSARGIICGLTQFTNKCHIAFAALEAVCFQTREILDAMNRDCGIPLSHLQVDGGMTSNKILMQLQADILYIPVVKPSMPETTALGAAMAAGAAEGVGVWSLEPEDLSAVTMERFEPQINAEESEIRYSTWKKAVMKSMGWVTTQSPESGDPSIFCSLPLGFFIVSSMVMLIGARYISGIP
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.
What are the official names of this protein?
Glycerol kinase, GK, Glycerokinase, ATP:glycerol 3-phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=In sperm and fetal tissues, the majority of the enzyme is bound to mitochondria, but in adult tissues, such as liver found in the cytoplasm.
Protein: YEG5_SCHPO
Sequence: MNLEFSFGNLIAKNTENSTKEEGTWEVNKLMKFSSEEGRSSSDDYMFSSPDFEKAGNGDAEMREFFNFDGLPDQGLNLPSIAPPSLSHASSPNLSNSQDEAECLPSDRQQDYINPSLHLNRTVFPTPQHSISDANFLANTVDQPLGDNPMFGESDVYLLKMDPMKQAPYEAGFNSVKSSGAIEDPLQFRQPITMLETPFNESINTLTPYAEDYAFSSLNTSAPPLSNKEYAFSVNHLPAINEHKWKSRVETNMLFELRIKSNDNQSVPFEYLRLPSWAHREDKKRSSKPQPLQPDPETVIHLVPTVLAGDKSSVVKTCCTRCLLRERKRNARSQATKDACMPNYTKLKAYERNMTDASPEEKQQFRIKLLNQFPKLEDIDEDRMIMVFTGPEYVRLQLDGNERVAHINARITCYSSHQSCPYFHIIWDLYSMSRLVDRLVFPEPVTVLDDHKSRNLTKSEKTGKSNSQQAPSNHVLSKSNTVPNLVTGFPTRSDNPPNEKRRRTSSSENSRALDIQLSASDSHSPNSKSTLKSVEGSAFSMSKSPSVLSMTTPSGVSPSISKNGFHVVRVPSDAAGFQQRQQQEEGVLEAHTNESAPIAPFPYCTDDFSFSVEEKSSVNNLLTQFDEVAKPDFVSTPIKENVDSSFINMTPPDVSHAPLISRIIPNKGSIMGGYEVTILGANFFNGLVCLFGDNPAAVTFSWSESTIIATCPPATNAGTVPVTFQNYNSSSEAPVMFTYEDNLDNELYKLTVQVLGLKLTGSIQNPLTLSKKLLSSWRDDFAQYITNSIKQPPNSESKGQSKKTLLHDSNMESLKSVISRIVKKDSNQSDDSVESTILAAFALVTDTTTPYLSDFSLVNESGRSLLHLTAACGLSNASTFLCNAGCDVNKRDALGYTPLHYASLYDHKDICVNLLSNGAKPDVIGASGKKPIDLSSSEPIKLVFKEANNEQAQSISRSLIKDSEGSINTNETLESTSIVNEIEESAVQTKSYSESMWNKTVTMFPSLQELPQNYMSEVPSMMQKAMLSTLKSISAIPDDVPPPYSEFADDTTAQAGSSKRDSAISEDPDHHKSVWWSLRWQSRLVGRGKSTALTPEETRAIQEQAKTLKKAGMDFMLFSFWLPALLLLSIFGLRSYAQMIGGYLYRCIIGI
What are the official names of this protein?
Ankyrin and IPT/TIG repeat-containing protein C26H5.05.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass membrane protein.
Protein: RL4_STAAB
Sequence: MANYDVLKLDGTKSGSIELSDAVFGIEPNNSVLFEAINLQRASLRQGTHAVKNRSAVSGGGRKPWKQKGTGRARQGTIRAPQWRGGGIVFGPTPRSYAYKMPKKMRRLALRSALSFKAQENGLTVVDAFNFEAPKTKEFKNVLSTLEQPKKVLVVTENEDVNVELSARNIPGVQVTTAQGLNVLDITNADSLVITEAAAKKVEEVLG
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RK22_EUCGG
Sequence: MRKKRNKNLYGEVYALGQHISMSAHKARRVIDQIRGRSYEETLMILELMPYRACYPIFKLVYSAAANASHNMGFNEASLVISKAEVNEGTTMKKLKPRARGRSYAIKRPTCHIRIVLKDKSFYEEENFFCLKQSEWKKKKKYTDMTYHYMDKGGGLWDKK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LYSX_MYCBT
Sequence: MGLHLTVPGLRRDGRGVQSNSHDTSSKTTADISRCPQHTDAGLQRAATPGISRLLGISSRSVTLTKPRSATRGNSRYHWVPAAAGWTVGVIATLSLLASVSPLIRWIIKVPREFINDYLFNFPDTNFAWSFVLALLAAALTARKRIAWLVLLANMVLAAVVNAAEIAAGGNTAAESFGENLGFAVHVVAIVVLVLGYREFWAKVRRGALFRAAAVWLAGAVVGIVASWGLVELFPGSLAPDERLGYAANRVVGFALADPDLFTGRPHVFLNAIFGLFGAFALIGAAIVLFLSQRADNALTGEDESAIRGLLDLYGKDDSLGYFATRRDKSVVFASSGRACITYRVEVGVCLASGDPVGDHRAWPQAVDAWLRLCQTYGWAPGVMGASSQGAQTYREAGLTALELGDEAILRPADFKLSGPEMRGVRQAVTRARRAGLTVRIRRHRDIAEDEMAQTITRADSWRDTETERGFSMALGRLGDPADSDCLLVEAIDPHNQVLAMLSLVPWGTTGVSLDLMRRSPQSPNGTIELMVSELALHAESLGITRISLNFAVFRAAFEQGAQLGAGPVARLWRGLLVFFSRWWQLETLYRSNMKYQPEWVPRYACYEDARVIPRVGVASVIAEGFLVLPFSRRNRVHTGHHPAVPERLAATGLLHHDGSAPDVSGLRQVGLTNGDGVERRLPEQVRVRFDKLEKLRSSGIDAFPVGRPPSHTVAQALAADHQASVSVSGRIMRIRNYGGVLFAQLRDWSGEMQVLLDNSRLDQGCAAEFNAATDLGDLVEMTGHMGASKTGTPSLIVSGWRLIGKCLRPLPNKWKGLLDPEARVRTRYLDLAVNAESRALITARSSVLRAVRETLFAKGFVEVETPILQQLHGGATARPFVTHINTYSMDLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHAGYLEWIDGCRELIQNAAQAANGAPIAMRPRTDKGSDGTRHHLEPVDISGIWPVRTVHDAISEALGERIDADTGLTTLRKLCDAAGVPYRTQWDAGAVVLELYEHLVECRTEQPTFYIDFPTSVSPLTRPHRSKRGVAERWDLVAWGIELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGIDRVVMLITGRSIRETLPFPLAKPH
What is the function of this protein?
Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge.  LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M. tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins).  In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).
What are the official names of this protein?
Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CHSY_ARAAL
Sequence: MAPSLEEIRKAQRADGPAGILGIGTANPPNHVLQAEYPDYYFRITNSDHMTDLKEKFKRMCDKSMIRKRHMHLTEEFLKENPKMCAYMAPSLDTRQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDTSVGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLDEAFKPLGISDWNSLFWIAHPGGPAILDQVEIKLGLKAEKMRATRHVLSEYGNMSSACVLFILDEMRKKSAKDGAATTGEGLEWGVLFGFGPGLTVETVVLHSVPL
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase, Naringenin-chalcone synthase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: AROE_RHORT
Sequence: MITGKARVAGVIGWPVGHSRSPRLHGFWLARHGIDGAYVPLAVAPEALERALAALPALGLAGVNVTVPHKEHALARMDALTERARRIGAVNTIVCQSDGRLLGDNTDGFGFLENLRQRRPDWRAGHGPAVVLGAGGAARAVCASLLEAGCPALTLVNRDQGRARALAEALAAWSPVPITLATWDEAPRTLGGAALLVNTTSLGMVGQPPLDLDLRGLAPSALVTDIVYAPLETPLLARARALGLATVDGLGMLLHQGRPGFEAWFGVAPEVDDALRAAVLGKP
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: GYMN_GYMCH
Sequence: KTCENLADDY
What is the function of this protein?
Exerts antifungal activity against F. oxysporum and M. arachidicola, with an IC(50) of 2 uM for the former fungus and 10 uM, respectively.  Has weak mitogenic activity against murine splenocytes.  Displays antiproliferative activity on a human hepatoma cell line and mouse leukemia cell lines.  Inhibits human immunodeficiency virus-1 (HIV-1) reverse transcriptase.
What are the official names of this protein?
Gymnin.