PharMolix/UniProtQA huggingface dataset:
Protein: POLN_HEVBU
Sequence: MEAHQFIKAPGITTAIEQAALAAANSALANAVVVRPFLSHQQIEILINLMQPRQLVFRPEVFWNHPIQRVIHNELELYCRARSGRCLEIGAHPRSINDNPNVVHRCFLRPVGRDVQRWYTAPTRGPAANCRRSALRGLPAADRTYCLDGFSGCNFPAETGIALYSLHDMSPSDVAEAMFRHGMTRLYAALHLPPEVLLPPGTYRTASYLLIHDGRRVVVTYEGDTSAGYNHDVSNLRSWIRTTKVTGDHPLVIERVRAIGCHFVLLLTAAPEPSPMPYVPYPRSTEVYVRSIFGPGGTPSLFPTSCSTKSTFHAVPAHIWDRLMLFGATLDDQAFCCSRLMTYLRGISYKVTVGTLVANEGWNASEDALTAVITAAYLTICHQRYLRTQAISKGMRRLEREHAQKFITRLYSWLFEKSGRDYIPGRQLEFYAQCRRWLSAGFHLDPRVLVFDESAPCHCRTAIRKALSKFCCFMKWLGQECTCFLQPAEGAVGDQGHDNEAYEGSDVDPAESAISDISGSYVVPGTALQPLYQALDLPAEIVARAGRLTATVKVSQVDGRIDCETLLGNKTFRTSFVDGAVLETNGPERHNLSFDASQSTMAAGPFSLTYAASAAGLEVRYVAAGLDHRAVFAPGVSPRSAPGEVTAFCSALYRFNREAQRHSLIGNLWFHPEGLIGLFAPFSPGHVWESANPFCGESTLYTRTWSEVDAVSSPARPDLGFMSEPSIPSRAATPTLAAPLPPPAPDPSPPPSAPALAEPASGATAGAPAITHQTARHRRLLFTYPDGSKVFAGSLFESTCTWLVNASNVDHRPGGGLCHAFYQRYPASFDAASFVMRDGAAAYTLTPRPIIHAVAPDYRLEHNPKRLEAAYRETCSRLGTAAYPLLGTGIYQVPIGPSFDAWERNHRPGDELYLPELAARWFEANRPTRPTLTITEDVARTANLAIELDSATDVGRACAGCRVTPGVVQYQFTAGVPGSGKSRSITQADVDVVVVPTRELRNAWRRRGFAAFTPHTAARVTQGRRVVIDEAPSLPPHLLLLHMQRAATVHLLGDPNQIPAIDFEHAGLVPAIRPDLGPTSWWHVTHRWPADVCELIRGAYPMIQTTSRVLRSLFWGEPAVGQKLVFTQAAKPANPGSVTVHEAQGATYTETTIIATADARGLIQSSRAHAIVALTRHTEKCVIIDAPGLLREVGISDAIVNNFFLAGGEIGHQRPSVIPRGNPDANVDTLAAFPPSCQISAFHQLAEELGHRPVPVAAVLPPCPELEQGLLYLPQELTTCDSVVTFELTDIVHCRMAAPSQRKAVLSTLVGRYGGRTKLYNASHSDVRDSLARFIPAIGPVQVTTCELYELVEAMVEKGQDGSAVLELDLCNRDVSRITFFQKDCNKFTTGETIAHGKVGQGISAWSKTFCALFGPWFRAIEKAILALLPQGVFYGDAFDDTVFSAAVAAAKASMVFENDFSEFDSTQNNFSLGLECAIMEECGMPQWLIRLYHLIRSAWILQAPKESLRGFWKKHSGEPGTLLWNTVWNMAVITHCYDFRDFQVAAFKGDDSIVLCSEYRQSPGAAVLIAGCGLKLKVDFRPIGLYAGVVVAPGLGALPDVVRFAGRLTEKNWGPGPERAEQLRLAVSDFLRKLTNVAQMCVDVVSRVYGVSPGLVHNLIGMLQAVADGKAHFTESVKPVLDLTNSILCRVE
What is the function of this protein?
RNA-directed RNA polymerase: Plays an essential role in the virus replication (By similarity).  Binds to the 3'-end of the genomic RNA to initiate viral replication (By similarity).
What are the official names of this protein?
Non-structural polyprotein pORF1.
What is the protein family that this protein belongs to?
Belongs to the hepevirus non-structural polyprotein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: APMLB_ARTPE
Sequence: MGLSEKVEFKTLDGLVLRGFLYSARAKGPAIVMTPGFNFPVSLLYHEVALGFQAAGITALVYDPRSVGRSDGLPRSDINPAKQSEDFSDAITFLKTKPVVDPKRIALWGYSLSAAAALMAAGLDPRVKLVVAVCPAPVPYNFEAPGKRRKYLDLAIRDRESQARGKEPFYVQYIGDSEETALFDYRKQRGMEELEYDEVVENLTKIAPGFRNEVTIQTLRRLGSWSFADVPQRVGPTPVLQVFAVHEELEHIRKTQEAIWAGLTGPKERHTEDRGHMDVLTPDGHRFAHLVKVQVDFVLKNFAQRMR
What is the function of this protein?
Thiohydrolase; part of the gene cluster that mediates the biosynthesis of phaeospelide A, a fungal polyene macrolide with a 34-membered macrolactone ring and an all-trans conjugated hexaene structure (PubMed:31180682).  The HR-PKS ApmlA uses acetyl-CoA and malonyl-CoA as its starter and extender units, respectively, and provides the large carbon framework in phaeospelide via 16 cycles of polyketide chain elongation, which is the largest number identified in fungal iterative PKSs thus far (PubMed:31180682).  During round 1, the KR domain reduces beta -ketone to an L-oriented hydroxy group, while during later rounds, it provides hydroxy groups in the D-configuration (PubMed:31180682).  The characteristic conjugated hexaene moiety is built during the later rounds (10-15), when the KR and DH domains are at work but ER is off (PubMed:31180682).  Phylogenetic analysis of the DH domain suggests that a polyene formation is programmed in the DH domain (PubMed:31180682).  Finally, the mature ACP-tethered carbon chain is transferred to the serine residue of the thiohydrolase apmlB, followed by intramolecular macrolactonization, generating phaeospelide A (PubMed:31180682).  When one elongation cycle during rounds 7-9 is skipped, phaeospelide B is biosynthesized instead (PubMed:31180682).
What are the official names of this protein?
Thiohydrolase apmlB, TH, Phaeospelide A biosynthesis cluster protein apmlB.
What is the protein family that this protein belongs to?
Belongs to the polyketide transferase af380 family.
Protein: RRF_FRATH
Sequence: MINDILKDAENRMKKSLEVLADDLAKIRTGRAHPDLLAHVTIDYYGVETPITQAANITVLDARTLGITPWEKGLSSKIEKAILTSDLGLNPTNLGDSLRVPMPALNEERRKELVKLVKSETEAGRVSIRNIRRDANGDIKELLKEKEITEDQAKKAEDDIQKITDKMIAQADALAAKKEQDLMAV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_LEPIN
Sequence: MSANKLKVSVISPEKILYKGEVDSLIVPGSEGFFGILPNHAPLVATLGIGILEIRKGEKLKVLSVEGGFVEIKDNSISILTDHGALKEDIDLEVEKKNLAEAEKLPPSDSKNLFLQKTKTRILVASR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CL158_CAEEL
Sequence: MQKFILSAFVVALVAADCALKCPDGYFSFKRAPSAKNSMTGLWCVKAILSDTLISPNQAKQVCEKDGSILTSFENLDERTKLATVLRDFLSAKKLDRGGMIVDGHRLKNCETDDRTVLNAEPCRNSSTGFTTDEKHTDNTFMWKSWADTEPGQSIFEKQIESCLQLAISQFKSRTELINDVFCNYVKHPQNEGAYDLWNYGAVCGRLPEWN
What are the official names of this protein?
C-type lectin domain-containing protein 158.
Protein: RIR2H_MYCBP
Sequence: MTRTRSGSLAAGGLNWASLPLKLFAGGNAKFWDPADIDFTRDRADWEKLSDDERDYATRLCTQFIAGEEAVTEDIQPFMSAMRAEGRLADEMYLTQFAFEEAKHTQVFRMWLDAVGISEDLHRYLDDLPAYRQIFYAELPECLNALSADPSPAAQVRASVTYNHIVEGMLALTGYYAWHKICVERAILPGMQELVRRIGDDERRHMAWGTFTCRRHVAADDANWTVFETRMNELIPLALRLIEEGFALYGDQPPFDLSKDDFLQYSTDKGMRRFGTISNARGRPVAEIDVDYSPAQLEDTFADEDRRTLAAASA
What is the function of this protein?
Probable oxidase that might be involved in lipid metabolism.
What are the official names of this protein?
R2-like ligand binding oxidase, Ribonucleotide reductase R2 subunit homolog, Ribonucleotide reductase small subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily.
Protein: CT51_CONIM
Sequence: MYCLPVFIILLLLISSAPSTPPQPRNKDRVHLISLLDNHKQILQRDWNSCCGKNPGCCPWGK
What are the official names of this protein?
Conotoxin Im5.1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPD_NEIM0
Sequence: MKRKNIALIPAAGIGARFGADKPKQYVEIGSKTVLEHTIGIFERHEAVDLTVVVVSPEDTFADKVQTAFPQVRVWKNGGQTRAETVRNGVAKLLEIGLASADDNILVHDAARCCLPSEALTRLIEQAGNAAEGGILAISIADTLKRAEGGQISATVERTSLWQAQTPQLFRAGLLHRALAAENLDGITDEASAVEKLGIRPLLVQGDARNLKLTQPQDAYIVRLLLNAV
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: TFDP3_HUMAN
Sequence: MAKYVSLTEANEELKVLMDENQTSRPVAVHTSTVNPLGKQLLPKTFGQSSVNIDQQVVIGMPQRPAASNIPVVGSPNPPSTHFASQNQHSYSSPPWAGQHNRKGEKNGMGLCRLSMKVWETVQRKGTTSCQEVVGELVAKFRAASNHASPNESAYDVKNIKRRTYDALNVLMAMNIISREKKKIKWIGLTTNSAQNCQNLRVERQKRLERIKQKQSELQQLILQQIAFKNLVLRNQYVEEQVSQRPLPNSVIHVPFIIISSSKKTVINCSISDDKSEYLFKFNSSFEIHDDTEVLMWMGMTFGLESGSCSAEDLKMARNLVPKALEPYVTEMAQGTFGGVFTTAGSRSNGTWLSASDLTNIAIGMLATSSGGSQYSGSRVETPAVEEEEEEDNNDDDLSENDEDD
What is the function of this protein?
Competitive inhibitor of E2F-mediated transactivation activity.  Impairs E2F-mediated cell-cycle progression from G(1) to S phase.
What are the official names of this protein?
Transcription factor Dp family member 3, Cancer/testis antigen 30, CT30, Hepatocellular carcinoma-associated antigen 661.
What is the protein family that this protein belongs to?
Belongs to the E2F/DP family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Translocates to the nucleus on heterodimerization with E2F family members.
Protein: PIM3_RAT
Sequence: MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKVYQVGAVLGSGGFGTVYAGSRIADGLPVAVKHVVKERVTEWGSLGGMAVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFLLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHNCGVVHRDIKDENLLVDLRSGELKLIDFGSGAVLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEQDEEILRGRLFFRRRVSPECQQLIEWCLSLRPSERPSLDQIAAHPWMLGTEGSVPENCDLRLCALDTDDGASTTSSSESL
What is the function of this protein?
Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis and promote cell survival and protein translation.  May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which induces release of the anti-apoptotic protein Bcl-X(L), the regulation of cell cycle progression and protein synthesis and by regulation of MYC transcriptional activity.  Additionally to this role on tumorigenesis, can also negatively regulate insulin secretion by inhibiting the activation of MAPK1/3 (ERK1/2), through SOCS6.  Involved also in the control of energy metabolism and regulation of AMPK activity in modulating MYC and PPARGC1A protein levels and cell growth (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase pim-3, Kinase induced by depolarization, Protein kinase Kid-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACR_STAES
Sequence: MNKYDRLDEITKLVNKRGSVRTNEIVEDLNVSDMTVRRDLAELEEKGVLTKIHGGARSNSAFQYKEMSHQEKHTRFIEEKRFIAKNAVDLIEDGDTIFLGPGTTVQKLAEEINHYSLTIITNCLPVFNILIKKQTLHFRVYLLGGEMRDLTEAFVGEMTNQLLSQLRFSKMFFSSNGVKDGLAMTSSIEEAYTQQIALSHSLEKYLLIDSSKIGKDDFSSFCELRELNAVLTDNNDLEKKEKIESYVEVIS
What is the function of this protein?
Repressor of the lactose catabolism operon.  Galactose-6-phosphate is the inducer (By similarity).
What are the official names of this protein?
Lactose phosphotransferase system repressor.
Protein: KDSA_ECOBW
Sequence: MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPSQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEGGNEKVILCDRGANFGYDNLVVDMLGFSIMKKVSGNSPVIFDVTHALQCRDPFGAASGGRRAQVAELARAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEPFLKQMKAIDDLVKGFEELDTSK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_BORPD
Sequence: MKRTYQPSVTRRKRTHGFRVRMKTRGGRAVLNARRAKGRKRLAV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: CHEY_TREPA
Sequence: MISKQDFPTINDRVPAGQKPNGAPYRVLVVDDSMFVSKQIGQILTSEGYEVADTAVDGVDGVEKYKAMSPGVDLVTMDITMPKMDGITALEKILEFDKNAKVVIISALGKEELVKKALLLGAKNYIVKPLDRKKVLERIASVLK
What is the function of this protein?
Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors.  CheY seems to regulate the clockwise (CW) rotation (By similarity).
What are the official names of this protein?
Chemotaxis protein CheY.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAPS_CATRO
Sequence: MIGSVKRPVVSCVLPEFDFTESTGLGKKSSSVKLPVNFGAFGSGGGEVKLGFLAPIKATEGSKTSSFQVNGKVDNFRHLQPSDCNSNSDSSLNNCNGFPGKKILQTTTVGNSTNILWHKCAVEKSERQEPLQQRGCVIWITGLSGSGKSTLACALSRGLHAKGKLTYILDGDNVRHGLNSDLSFKAEDRAENIRRIGEVAKLFADAGVICIASLISPYRKPPDACRSLLPEGDFIEVFMDVPLKVCEARDPKGLYKLARAGKIKGFTGIDDPYEPPLKSEIVLHQKLGMCDSPCDLADIVISYLEENGYLKA
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, chloroplastic, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase, APS kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YEGS_ECO57
Sequence: MAEFPASLLILNGKSTDNLPLREAIMLLREEGMTIHVRVTWEKGDAARYVEEARKLGVATVIAGGGDGTINEVSTALIQCEGDDIPALGILPLGTANDFATSVGIPEALDKALKLAIAGNAIAIDMAQVNKQTCFINMATGGFGTRITTETPEKLKAALGGVSYIIHGLMRMDTLQPDRCEIRGENFHWQGDALVIGIGNGRQAGGGQQLCPNALINDGLLQLRIFTGDEILPALVSTLKSDEDNPNIIEGASSWFDIQAPHEITFNLDGEPLSGQNFHIEILPAALRCRLPPDCPLLR
What is the function of this protein?
Probably phosphorylates lipids; the in vivo substrate is unknown.
What are the official names of this protein?
Probable lipid kinase YegS.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA2_CHLCV
Sequence: MRAWEDFLLLQEKEIGTSTVDKWLRSLKVLCFDACNLYLEAKDSFQVTWFEEHIRHKVKTSLVNNNGKLIRVHITSLDKTAPFYKEKQIQQEKTAYFTMQYGNVNPEMTFGNFLVTPENDLPFRILQEFTKPAEDTAGFPFNPIYLFGPEGSGKTHLMQAAVNALREFGGKILYVASDLFTEHLVSAIRSGEMQRFRSFYRNVDALFIEDIEVFSGKGATQEEFFHTFNSLQTEGKLIVISSAYAPADLKAMEERLISRFEWGVAVPIHPLTKEGLRSFLMHQAEQLSVRIEDTALDFLIHALSSNVKTLIDALKLLSKRVAYKKLAQQLLYEDDIQTLLHDVLEVAESVRLTPSGIVRAVAKYYGVSPESILGRSQSREYVLPRQVSMYLCRQKLSLSYVRIGDVFSRDHSTVISSIRAISQKVEEGGDDISIATQELMKSLTSAYKSLEFFPEEEISC
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids (By similarity).
What are the official names of this protein?
Chromosomal replication initiator protein DnaA 2.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_VIBA3
Sequence: MAKNIQAIRGMNDCLPTQSPLWQKVESAVKSVVSAYGYNEVRMPIVEETNLFSRAVGEETDVVSKEMYTFDDRNGDSLTLRPEGTAGCVRSCIQNSLINRDEQRLWYMGPMFRHERPQKGRYRQFHQCGVEVFGLDGPDVDAELIMMTARLWRELGIDKHVRLELNSIGSQEDRVSYRTALVAFLEQHIDVLDEDCKRRMHTNPLRVLDTKNPDVQAILGDAPRLSEYLGEESKQHFAGLCELLDAVGIEYQVNERLVRGLDYYNRTVFEWITDSLGAQGTVCGGGRYDGLVEQLGGKATNAVGFAMGLERLVLMMETLELTEVRRSVDVYMVAAGEGTMIAGMQLANQLRDTVEGVRVMNHFGGGNFKKQFKRADKVGAVVALVLGENEVADNTVVLKDLVGGEQQTVSQTEVAEKVAALI
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTC19_RAT
Sequence: MFRLLRWRLGRTLLRAAGRRCGGCTARLLPERAGDAGPGAERLRTRGAPARGHRVLPLLAALAWFSRTAAAEEQPGEDATDEAEAEIIQLLKRAKLSIMKDEPEAAELILHDALRLAYESDNKKAITYTYDLMANLAFIRGQLENAEQLFKATMSYLLGGGMKQEDNAIVEISLKLANIYAAQNKQEFALAGYEFCISTLEGKIEREKELAEDIMSEERANTYLLLGMCLDSCARYLLFSKQLSQAQRMYEKALQICQEIQGERHPQTIVLMSDLATALDAQGHFDDAYIYMQRASDLAREINHPELHMVLSNLAAILIHRERYTQAKEIYQEALKQAELKRDEFSVQHIREELAELSRKSRLLT
What is the function of this protein?
Required for the preservation of the structural and functional integrity of mitochondrial respiratory complex III by allowing the physiological turnover of the Rieske protein UQCRFS1.  Involved in the clearance of UQCRFS1 N-terminal fragments, which are produced upon incorporation into the complex III and whose presence is detrimental for its catalytic activity.
What are the official names of this protein?
Tetratricopeptide repeat protein 19, mitochondrial, TPR repeat protein 19.
What is the protein family that this protein belongs to?
Belongs to the TTC19 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: YC93_SCHPO
Sequence: MDELLNVASHAATFATNFALKHSISFAGKLAVQQVSSYIKRASADDQSELESVKTQLLEMIRVVTPAIELIEIMSVGENENFKSTKQLVDSLHADIEQFTKHVLSAAHSEFPPSSEKETLQKNVDTSILREMKTLLLKINDAVPLLNLSITTSGASISSSLPKSTSFSQLLRANSYIYRANVAFTGNEPLQVGPTFFLRTYKIIDNHAKSGYISNDLVMWKEEMPVCIAKMFRMPPQRLKSKDTVLAYALSLKQSFDDDRYHDEDETPVTKTISLNDVRTLFFSLSGKLLRLDDVQTPVLLLKYADDETEYSSNTAPSNWIALEALPLVSIPNESLDESDELAESLSDSEAARLQLLGIKKQESVAKKKSSFPSTIKDQPNLTLLEYLIRLCALESTTQESVLQLPDEQIALYLKDYQGRERPRDPASYNALENRSELSASPGSVSSSRHSGIFATPTFLSPWNIKNIPLVTPEVSTRQTKNVDEEDSALLMASPSVRKSNLLPQEDLISKDSVIKLKENPSVIPHSEPESSSKVINCQAKLNVEKEKKNP
What are the official names of this protein?
RanBD1 domain-containing protein C584.03c.
What are the subcellular locations of this protein?
Nucleus.
Protein: SETD3_HUMAN
Sequence: MGKKSRVKTQKSGTGATATVSPKEILNLTSELLQKCSSPAPGPGKEWEEYVQIRTLVEKIRKKQKGLSVTFDGKREDYFPDLMKWASENGASVEGFEMVNFKEEGFGLRATRDIKAEELFLWVPRKLLMTVESAKNSVLGPLYSQDRILQAMGNIALAFHLLCERASPNSFWQPYIQTLPSEYDTPLYFEEDEVRYLQSTQAIHDVFSQYKNTARQYAYFYKVIQTHPHANKLPLKDSFTYEDYRWAVSSVMTRQNQIPTEDGSRVTLALIPLWDMCNHTNGLITTGYNLEDDRCECVALQDFRAGEQIYIFYGTRSNAEFVIHSGFFFDNNSHDRVKIKLGVSKSDRLYAMKAEVLARAGIPTSSVFALHFTEPPISAQLLAFLRVFCMTEEELKEHLLGDSAIDRIFTLGNSEFPVSWDNEVKLWTFLEDRASLLLKTYKTTIEEDKSVLKNHDLSVRAKMAIKLRLGEKEILEKAVKSAAVNREYYRQQMEEKAPLPKYEESNLGLLESSVGDSRLPLVLRNLEEEAGVQDALNIREAISKAKATENGLVNGENSIPNGTRSENESLNQESKRAVEDAKGSSSDSTAGVKE
What is the function of this protein?
Protein-histidine N-methyltransferase that specifically mediates 3-methylhistidine (tele-methylhistidine) methylation of actin at 'His-73' (PubMed:30526847, PubMed:30626964, PubMed:30785395, PubMed:31388018, PubMed:31993215).  Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery (PubMed:30626964).  Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin (PubMed:30626964, PubMed:30785395, PubMed:31388018).
What are the official names of this protein?
Actin-histidine N-methyltransferase, Protein-L-histidine N-tele-methyltransferase, SET domain-containing protein 3, hSETD3.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. SETD3 actin-histidine methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes mainly in the cytoplasm.
Protein: RNH2_CAMJD
Sequence: MKTLFDTKELLNEFDINLIGIDEAGRGALAGPMMMAACKLNKKLDGLCDSKKLSEKKREELYEIIIKNSNYLILAFSSEQIDTLGLSTCLKTGLKLIKKHFKAENNFLYDGNTNLGINGIKTQIKADTSILQVSAASILAKVSKDKVMNFLAKDFPCYEFEKNKAYGTKAHKEVIAKFGICKLHRKSFKLL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNY_CAMHC
Sequence: MIEFLIGLIAAVVGILVGYLIARKINNANYEIFLEQAKAKAKAIEFEAEGILRNSKISVQEAEFEAKKAYEDKALKLQKDYNAKFDEISKKEQTVLTEQEILKDSREELEKEKKSAQTIYDEGTSLKKTYETKVEESLKLLERVAGLTEDEAKSEILQKVEEKSRAEIAHIVRKYEEEAKKEAKRNANYILAQATTRYAGEYAAERLINVVNIKNDDLKGRIIGKDGRNIKTLEMISGVDVIIDDTPNAIILSSHNLYRRAIAVRTVELLVEDGRIQPARIEDVYKKVSEEFEAGIQEEGENIVMDLGLTKIHPEIVKLIGKLKFRASYGQNALIHSLEVAHLAGIIAAETGGDENLARRAGILHDIGKALTHEFEGSHVDLGAEICKRYKENPVVINAIYAHHGHEEPTSVESAAVCTADVLSAARPGARREVLEAFLKRVSEIENIATSKEGVKQAYAINAGREIRVIANAKLVNDDEAVLLAKEIAEEIQAKVQYPGEIKVNIIRETRAVDYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PLSX_NOSP7
Sequence: MGSTRVRIAIDAMGGDHAPGEIVAGALRAKEELGVEILLVGDPQQIEAALPPKTNLAQVEIVPAEEAIAMDEEPLNAVRRKRKASINVAMDLVKQQKADAVFSAGHSGAAMASALLRLGRLPGIDRPAIGTVFPTIVAGKPVLVLDVGANVDCRPKFLEQFAVMGSAYSQYVLGTTEPKVGLLNIGEEDSKGNDAAVRAHQLLRENSQINFIGNAEGRDVLSGHFDVIVCDGFVGNVLLKFAEAVGEVILQILREELPQGLHGQIGSAFLKPNLKRVKQRMDHAEHGGALLLGVAGVCFIGHGSSQAPSIFNAIRMAKEAVDNQVLQRIQSQYILERESG
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: PTP61_DROME
Sequence: MSEQKTSGSGSAAAARLQIEAEYKDKGPQWHRFYKEICETCDREAKEKQFSTSESERHTNRGLNRYRDVNPYDHSRIVLKRGSVDYINANLVQLERAERQYILTQGPLVDTVGHFWLMVWEQKSRAVLMLNKLMEKKQIKCHLYWPNEMGADKALKLPHVKLTVELVRLETYQNFVRRWFKLTDLETQQSREVMQFHYTTWPDFGIPSSPNAFLKFLQQVRDSGCLSRDVGPAVVHCSAGIGRSGTFCLVDCCLVLIDKYGECNVSKVLCELRSYRMGLIQTADQLDFSYQAIIEGIKKLHDPTFLDAEEPLISNDTETHTLDELPPPLPPRVQSLNLPLAPNSGGILSLNMRAAQANGAESIGKELSKDALNNFINQHDMIHDAEVADSRPLPPLPVRAFNDSDSDEDYLLDDDDEDDTDEDEEYETINEHDADPVNGHVPATTQPHADDVNANNEKPAVPVDEQHKANGIDPIPGQLPASPENELKRRKRNEYQASLEQKVNDMKRKQRENEDKQLAAKKRRSLLTYIAAGVVVGVICAYAYTKLG
What is the function of this protein?
Non-receptor protein tyrosine phosphatase required for maintaining Dock in its non-phosphorylated state.
What are the official names of this protein?
Tyrosine-protein phosphatase non-receptor type 61F, dPTP61F.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.
What are the subcellular locations of this protein?
[Isoform A]: Cytoplasm. Endomembrane system. Note=Associates with the membranes of the reticular network and the mitochondria. SUBCELLULAR LOCATION: [Isoform B]: Nucleus.
Protein: ARAG_PSE14
Sequence: MQQAIEQTSINGALRFNGIGKVFPGVKALSDISFEARPGSVHALMGENGAGKSTLLKILGGSYQPNSGTLQIGEQSYQFKSTAESIAAGVAVIHQELHLVPEMTVAENLLLGHMPNRFGLINRGAMYRRAGELLKGLADEIDPRTRLGDLSLGQRQLVEIAKAMSRNAHVIAFDEPTSSLSAREIDRLMAIIVRLRDEGRVILYVSHRMEEIFRVCDAVTVFKDGRFVKTFEQMADLDHDRLVTCMVGRDIQNIYNYRPRQHQGPSLRVTGLLGPGLHEPVSFAVEKGEVLGFFGLVGAGRTELFRLLSGLTRSTAGTLQLDGKPLTLKSPRDSIEAGILLCPEDRKKEGIVPLSSVAENINIGARPRHVNLGCLIQGRWERDNARSQIKSMNVKTPSPEQQIMFLSGGNQQKAILGRWLSMPMKVLLLDEPTRGIDVGAKSEIYEIIHNLAADGIAVIVVSSDLMEVMGISDRILVMSEGAITGELNRDEADESRLLQLALPRTRS
What is the function of this protein?
Part of the ABC transporter complex AraFGH involved in arabinose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Arabinose import ATP-binding protein AraG.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GLPB_ECO27
Sequence: MRFDTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGSLDLLSHLPDGQPVTDIHSGLESLRQQAPAHPYTLLGPQRVLDLACQAQALIAESGAQLQGSVELAHQRITPLGTLRSTWLSSPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLRELDLKVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMILMPACFGLADDKLWHWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPGDEVKKVTCKNGVVNEIWTRNHADIPLRPRFAVLASGSFFSGGLVAERNGIREPILGLDVLQTATRGEWYKGDFFAPQPWQQFGVTTDEALRPSQAGQTIENLFAIGSVLGGFDPIAQGCGGGVCAVSALHAAQQIAQRAGGQQ
What is the function of this protein?
Conversion of glycerol 3-phosphate to dihydroxyacetone.  Uses fumarate or nitrate as electron acceptor.
What are the official names of this protein?
Anaerobic glycerol-3-phosphate dehydrogenase subunit B, Anaerobic G-3-P dehydrogenase subunit B, Anaerobic G3Pdhase B.
What is the protein family that this protein belongs to?
Belongs to the anaerobic G-3-P dehydrogenase subunit B family.