PharMolix/UniProtQA huggingface dataset:
Protein: PABA_SERMA
Sequence: MLLLIDNYDSFTYNLYQYFCELGAEVVVKRNDELQLTDIERLAPQHLVISPGPCTPNEAGISVAAIRHFAGKLPILGVCLGHQALGQAFGAEVVRARAVMHGKTSAIRHLGVGVFRGLSDPLTVTRYHSLVLKADTLPDCFEVTAWSERDGVRDEIMGIRHRALALEGVQFHPESVLSEQGHQLLDNFLNR
What is the function of this protein?
Part of a heterodimeric complex that catalyzes the two-step biosynthesis of 4-amino-4-deoxychorismate (ADC), a precursor of p-aminobenzoate (PABA) and tetrahydrofolate.  In the first step, a glutamine amidotransferase (PabA) generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC.  PabA converts glutamine into glutamate only in the presence of stoichiometric amounts of PabB (By similarity).
What are the official names of this protein?
Aminodeoxychorismate synthase component 2, ADC synthase, ADCS, 4-amino-4-deoxychorismate synthase component 2, Aminodeoxychorismate synthase, glutamine amidotransferase component.
Protein: COX1_DUGDU
Sequence: MFINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSILIRAELGQPGTLLGDDQIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMIEAGAGTGWTVYPPLAGNLAHGGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQTPLFVWSVLVTAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIATYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPALLWALGFIFLFTVGGLTGIVLANSSLDVVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNQTWAKIHFLIMFVGVNLTFFPQHFLGLSGMPRRYSDYPDAYTMWNTVSSMGSFISLTAVILMVFMVWEAFASKREVSTVELTTTNLEWLNGCPPSYHTFEEPAYVKI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NIFH_CHLP8
Sequence: MRKVAIYGKGGIGKSTTTQNTVAGLAEAGKKVMVVGCDPKADSTRLLLGGLQQKTVLDTLREEGEEVELEDIIKEGYKGSRCTESGGPEPGVGCAGRGIITSVNLLEQLGAYDDEWNLDYVFYDVLGDVVCGGFAMPIRDGKAEEIYIVCSGEMMAMYAANNICKGILKYADAGGVRLGGLICNSRKVDNEREMIEELARRIGTQMIHFVPRDNFVQRAEINRKTVIDYDPTHPQADEYRALARKIDENKMFVIPKPLEIDELESLLIEFGIAN
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
What are the official names of this protein?
Nitrogenase iron protein, Nitrogenase Fe protein, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: MUTS2_STRP1
Sequence: MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEAPKIEKSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLELSTDLNIQELLAIKKVLQSSSDMIHFYSDLDNVSFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPELERIRRQLTNSERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTVYIEPRAVVTLNEEITQLRADERHEEGRILHAFSDLLRPHVATIRNNAWILGHLDFVRAKYLFMSDNKATIPKISNDSTLALINVRHPLLSNPVANDLHFDHDLTAIVITGPNTGGKTIMLKTLGLAQLMGQSGLPVLADKGSKIAVFNNIFADIGDEQSIEQSLSTFSSHMTHIVSILNEADHNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYGIETNFVENASMEFDAETLSPTYRFMQGVPGRSNAFEIASRLGLAPFIVKQAKQMTDSDSDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKELEKIYQEAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKKIKAARAPRIGDDIIVTSYGQRGTLTSQLKDGRWEAQVGIIKMTLTQDEFSLVRVQEEQKVKNKQINVVKKADGSGPRARLDLRGKRYEEAMQELDHFIDQALLNNMGQVDIIHGIGTGVIREGVTKYLRRNKHVKHFAYAPQNAGGSGATIVTLG
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: CRIS3_HUMAN
Sequence: MTLFPVLLFLVAGLLPSFPANEDKDPAFTALLTTQTQVQREIVNKHNELRRAVSPPARNMLKMEWNKEAAANAQKWANQCNYRHSNPKDRMTSLKCGENLYMSSASSSWSQAIQSWFDEYNDFDFGVGPKTPNAVVGHYTQVVWYSSYLVGCGNAYCPNQKVLKYYYVCQYCPAGNWANRLYVPYEQGAPCASCPDNCDDGLCTNGCKYEDLYSNCKSLKLTLTCKHQLVRDSCKASCNCSNSIY
What are the official names of this protein?
Cysteine-rich secretory protein 3, CRISP-3, Specific granule protein of 28 kDa, SGP28.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted. Note=In neutrophils, localized in specific granules.
Protein: KCY_NITHX
Sequence: MIIAIDGPAASGKGTLGKRLAHHYHFRHLDTGVIYRAVAKALLDAGADPADEALAVAAALELDPEKFGHPALKTQTVGEVASVVSAFPRVREALLTFQRQFAAEPPGAVLDGRDIGTVICPEADVKIFVVADPVVRARRRTLEARSRGEEADEAVVLADILKRDERDRNRPIAPLKAAADAHVLDNSNLDIEAGLKAAIAIVEAVRAGR
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YVGL_BACSU
Sequence: MFKKYSIFIAALTAFLLVAGCSSNQSSTDSEKKVTLTISAAASAQDALEEIQKNYEKDHQHITIQDNYGSSGALQKQISQGAGADLFFSAAEDKFKKLVDDGDIAKKDSTELVGNEIVLVVPKNGDSPVTSFSNLAESEKIALGTPESVPAGAYGKESLTKLSLWDKVKDKIVYGKDVRQVLSYVETGNVDAGVVYKTDALVSKKVNIVDEAKADTHSPIVYPLGIVKDTKHRKEAKEFYEYLQSDEAMKVFEKYGFTAE
What are the official names of this protein?
Putative ABC transporter substrate-binding lipoprotein YvgL.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein ModA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: FLOT2_MOUSE
Sequence: MGNCHTVGPNEALVVSGGCCGSDYKQYVFGGWAWAWWCISDTQRISLEIMTLQPRCEDVETAEGVALTVTGVAQVKIMTEKELLAVACEQFLGKNVQDIKNVVLQTLEGHLRSILGTLTVEQIYQDRDQFAKLVREVAAPDVGRMGIEILSFTIKDVYDKVDYLSSLGKTQTAVVQRDADIGVAEAERDAGIREAECKKEMLDVKFMADTKIADSKRAFELQKSAFSEEVNIKTAEAQLAYELQGAREQQKIRQEEIEIEVVQRKKQIAVEAQEILRTDKELIATVRRPAEAEAHRIQQIAEGEKVKQVLLAQAEAEKIRKIGEAEAAVIEAMGKAEAERMKLKAEAYQKYGDAAKMALVLEALPQIAAKISAPLTKVDEIVVLSGDNSKVTSEVNRLLAELPASVHALTGVDLSKIPLIKNATGAQV
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.  May be involved in epidermal cell adhesion and epidermal structure and function.
What are the official names of this protein?
Flotillin-2, Epidermal surface antigen, ESA, Membrane component chromosome 17 surface marker 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family. Flotillin subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Endosome. Membrane; Lipid-anchor. Note=Membrane-associated protein of caveolae.
Protein: CH10_MYCA1
Sequence: MAKVNIKPLEDKILVQANEAETTTASGLVIPDTAKEKPQEGTVVAVGPGRWDDDGAKRIPLDVSEGDTVIYSKYGGTEIKYNGEEYLILSARDVLAVVSK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAEA_ECO57
Sequence: MKTLIRKFSRTAITVVLVILAFIAIFNAWVYYTESPWTRDARFSADVVAIAPDVSGLITQVNVHNQLVKKGQVLFTIDQPRYQKALEEAQADVAYYQVLAQEKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAPADGWVTNLNVYTGEFITRGSTAVALVKQNSFYVLAYMEETKLEGVRPGYRAEITPLGSNKVLKGTVDSVAAGVTNASSTRDDKGMATIDSNLEWVRLAQRVPVRIRLDNQQENIWPAGTTATVVVTGKQDRDESQDSFFRKMAHRLREFG
What is the function of this protein?
Forms an efflux pump with AaeB.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeA, pHBA efflux pump protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HEMH_CHLAB
Sequence: MVSTYLLANFGGPRHSHDVEVFLTSLLTDRDVTGGCLPSFLHKRLFSFIAKKRAPKVVPQYNCIGGYSPIYQDTEALAKTLSSHLDAPVITFHRYLPDTHSQTIQQLKTLGDLPVVGVPLFPHFTYAVTGSIVRFIHNHLPSLNISWVAHFGNHPQFISCMIDHILEFLQSHDIPTHDCCLLFSAHGLPMRYVNKGDPYNVQCEKSFAAISERLPNIETFLCYQSKFGLGKWLTPSTKEVCKTLKTNKKYVLIVPFGFTSDHIETLYEIEKEYIAILIDRKYQALRVPAIYQSPQWVQSLATIIQSTRYVEKHSLIKS
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_MYCBO
Sequence: MSGLPRSVPDVLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDAVQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGTNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRPEAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFRLGEPAAGELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGAIADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGASLHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACVLDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATAVRAVIR
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRAM_I79A7
Sequence: MNPNQKIITIGSVSIVLTTVGLLLQITSLCSIWFSHYNQVTQTNGQPCSNDTINYYNETFVNVTNVQNNYTTITEPSIPQAIHYSSGRDLCPVKGWAPLSKDNGIRIGSRGEVFVIREPFISCSINECRTFFLTQGALLNDKHSNGTVKDRSPFRTLMSCPIGVAPSPSNSRFESVAWSATACSDGPGWLTLGITGPDTTAVAVLKYNGVITDTLKSWKGNIMRTQESECVCQDEFCYTLVTDGPSDAQAFYKILKIKKGKIVGAKDVDATGFHFEECSCYPSGENVECVCRDNWRGSNRPWIRFNSDLDYQIGYVCSGVFGDNPRPVDGTGSCNSPVNNGKGRYGVKGFSFRYGDGVWIGRTKSLESRSGFEMVWDANGWVSTDKDSNGVQDIIDNDNWSGYSGSFSIRGETTGRNCTVPCFWVEMIRGQPKEKTIWTSGSSIAFCGVNSDTTSWSWPDGALLPFDIDK
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: IDI2_LACPL
Sequence: MPQSQQSHRKDEHVSLAEKYFHGEQANAFDQVRIRHDALPETAVADVDLATTVGQWHWDSPLYIEAMTGGSQRTGEINARLGRIAAACGLPIATGSQSVAIKDPQVAPTFATMRDHNPNGLIFGNLGAGHPLSAAQTAIAMLQADALELHLNVVQEIVMPEGDRDFHWLTNISDLVQALTVPVIVKEVGFGISRPTMQQLYAAGVRYLDLGGHGGTNFVDIENRRRANRDMAYLHDFGLTTVESLLGVQNRPDDLTVLAAGGVRQPLDILKALMLGADAVGMAGTVLHALLHHTDDEVIAMLTDWQSQLKRLFALVGVTRVDQFKSSRIQDKILLSPELVNYKQSIKD
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPAST_HUMAN
Sequence: MNSPGGRGKKKGSGGASNPVPPRPPPPCLAPAPPAAGPAPPPESPHKRNLYYFSYPLFVGFALLRLVAFHLGLLFVWLCQRFSRALMAAKRSSGAAPAPASASAPAPVPGGEAERVRVFHKQAFEYISIALRIDEDEKAGQKEQAVEWYKKGIEELEKGIAVIVTGQGEQCERARRLQAKMMTNLVMAKDRLQLLEKMQPVLPFSKSQTDVYNDSTNLACRNGHLQSESGAVPKRKDPLTHTSNSLPRSKTVMKTGSAGLSGHHRAPSYSGLSMVSGVKQGSGPAPTTHKGTPKTNRTNKPSTPTTATRKKKDLKNFRNVDSNLANLIMNEIVDNGTAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKDFGDTTV
What is the function of this protein?
Involved in lipid metabolism by regulating the size and distribution of lipid droplets.
What are the official names of this protein?
Spastin, Spastic paraplegia 4 protein.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. Spastin subfamily.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Endoplasmic reticulum. Midbody. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Cell projection, axon. Note=Forms an intramembrane hairpin-like structure in the membrane (PubMed:20200447). Localization to the centrosome is independent of microtubules (PubMed:15891913). Localizes to the midbody of dividing cells, and this requires CHMP1B (PubMed:18997780). Enriched in the distal axons and branches of postmitotic neurons (PubMed:15269182). Mainly nuclear in interphase cells and becomes associated with the centrosomes, spindle microtubules, midzone and finally the midbody during cell division (PubMed:15269182). SUBCELLULAR LOCATION: [Isoform 1]: Endoplasmic reticulum membrane; Peripheral membrane protein. Nucleus membrane. Lipid droplet. Cytoplasm, cytoskeleton. Endosome. Note=Forms an intramembrane hairpin-like structure in the membrane (PubMed:20200447). Recruited to nuclear membrane by IST1 during late anaphase (PubMed:26040712). Localizes to endoplasmic reticulum tubular network (PubMed:23969831). SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm. Endosome. Nucleus membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Constitutes the main endosomal form (PubMed:19000169). Recruited to nuclear membrane by IST1 during late anaphase (PubMed:26040712).
Protein: YG027_HUMAN
Sequence: MATFPGQVSTYFLAAWTGPGPATHWPLYAQLMPHSGLSRPSSCPGTSSPGPKLPQVGLSRPSCCLPAFSPGLALPPGCIYKTNSCLTTTFYGSAPAQLLPAFVGPKLPQVKLFRPTFCLAVACTDPALA
What are the official names of this protein?
Putative uncharacterized protein FLJ92257.
Protein: IOLE_BACC0
Sequence: MFKENTIKLGIAPIAWTNDDMPELGAENTFEQCISEMALAGFNGSEVGNKYPRNTVVLKKSLELRNLEIASAWFSTFLTTKPIEETVEEFIKHRDFLHDMGAKVIVVSEQGHSIQGLMDVPLFKNKPVFTEEEWDKLADGLHHLGKLAQEKGLHIVYHHHMGTGVQTTAEIEKLMDMTDPELVSLLFDTGHLVFSGEEPLYILKKYLSRIKHVHLKDIRQEVVDIVKENELSFLQAVKNGAFTVPGDGVIGFDKVFTILANSDYKGWFVVEAEQDPALANPFEYALKARKFIQEKAGL
What is the function of this protein?
Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).
What are the official names of this protein?
Inosose dehydratase, 2-keto-myo-inositol dehydratase, 2KMI dehydratase.
What is the protein family that this protein belongs to?
Belongs to the IolE/MocC family.
Protein: RS18_NEIMF
Sequence: MARQSFKRRKFCRFTAEKIQEVDYKQVDLLKDFISENGKIIPARITGTKAFYQRQLAVAVKRARFLALLPYTDQHK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: AL5AP_BOVIN
Sequence: MDQEAVGNIVLLAIVTLISVVQNGFFAHKVEHESKTHNGRSFQRTGTLAFERVYTANQNCVDAYPTFLVMLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIILFLFAMSLAGILNYFFIALFGSDFENYIKTVTTTISPLLLIP
What is the function of this protein?
Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase).  Anchors ALOX5 to the membrane.  Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5.  Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes (By similarity).
What are the official names of this protein?
Arachidonate 5-lipoxygenase-activating protein.
What is the protein family that this protein belongs to?
Belongs to the MAPEG family.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NINF_LAMBD
Sequence: MIDQNRSYEQESVERALTCANCGQKLHVLEVHVCEHCCAELMSDPNSSMHEEEDDG
What are the official names of this protein?
Protein ninF.
What is the protein family that this protein belongs to?
Belongs to the ninF family.
Protein: HNS_SHIFL
Sequence: MSEALKILNNIRTLRAQARECTLETLEEMLEKLEVVVNERREEESAAAAEVEERTRKLQQYREMLIADGIDPNELLNSLAAVKSGTKAKRAQRPAKYSYVDENGETKTWTGQGRTPAVIKKAMDEQGKSLDDFLIKQ
What is the function of this protein?
KcpA is involved in pathogenesis.  The protein is required by invading bacteria for spread into adjacent cells (colonic epithelial cells).  It is needed to establish kerato-conjunctivitis provocation (KCP) by pathogenic bacteria (PubMed:2668687).  It is involved in the thermal control of epithelial cell invasion (PubMed:1406252).
What are the official names of this protein?
DNA-binding protein H-NS, Pathogenesis protein KcpA.
What is the protein family that this protein belongs to?
Belongs to the histone-like protein H-NS family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: MUKF_ECO24
Sequence: MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAVATLNGERLDGEMSEGELVDAFRHVSDAFEQTSETIGVRANNAINDMVRQRLLNRFTSEQAEGNAIYRLTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAEEGGDEFHWHRNVYAPLKYSVAEIFDSIDLTQRLMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLRELQDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIGYDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDEPWALTYANADRLLDMRDEEMALRDEEVTGELPEDLEYEEFNEIREQLAAIIEEQLAVYKTRQVPLDLGLVVREYLSQYPRARHFDVARIVIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Not required for mini-F plasmid partitioning.  Probably acts via its interaction with MukB and MukE.  Overexpression results in anucleate cells.  It has a calcium binding activity.
What are the official names of this protein?
Chromosome partition protein MukF.
What is the protein family that this protein belongs to?
Belongs to the MukF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: TIG_FRAP2
Sequence: MQVTVEKKEGIHCSLLIEVPANEVDSIVTKEINKTAKTIKMDGFRPGKVPAGMVEKKYGEQIRMEVISDLIPQKYSKAIQDEKLAVAGIEVELKENKKGEPLKFVANLELFPEFEVTGFEKIEVQKPVVELTDKEVKQMIENLRKQLATFSEVERAVQKDDKVVIDFVGKRDGEVFEGGSANDQELVIGSGQMIPGFEDGIIGMNKDEQRTITVTFPEDYQNKDLAGKEATFDITVKKIQEAQLPEVDDEFVAKFGVKGGVDTFEDEIKENMQRELKFILQRKVKDQVFKGLREIAEFETPKALIKREIDAAKQNLVKQMGGGQNFDVNQLPDNLFEANAKQKVETSLILDSIIESQKFQAEDAEVESLLDELVQAYEEPEKTKEQIKKNDREISNLKGLVIENKLTDWVLSQAQVTEKQEDFFEVIKENMQAQQAGF
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: FMT_SPHAL
Sequence: MRIAFMGTPPFAVPTLAALHTAGHDIAAVYSQPPRPAQRGKKLQKSPVQLWAEEHGLPVRTPKSLKSDEAQAEFAALDLDVAVVAAYGLILPQAVLDAPREGCLNVHGSILPRWRGAAPVQRAILAGDAETGVTIMQMDAGLDTGAMRLIETTPVARKSAGLLTHELAEMGALMMRRVLSELHAFPPVPQPDEGVTYAAKIDKSEARLDFLVSAVQVERQVRAFNPAPGAFFELEGERYKVLAAEVVHPAETVAGAAPGVTIDDRLAIACNPGAIRVTRIQRAGKPAMEAGEMLRGRGIAKGTRLA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RS20_HALH5
Sequence: MKGNANIKSAIKRVKTNEKRRIQNASVKSALRTAIKQFEAKVENNDAEAAKAAFVEATKKLDKAANKGLIHKNAASRQKSRLAKKLNGLSA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: KCY_YERPG
Sequence: MTAIAPVITVDGPSGAGKGTLCKALAESLNWRLLDSGAIYRVLALAALHHQVDISTEEALVPLAAHLDVRFVSQNGQLQVILEGEDVSNEIRTETVGNTASQAAAFPRVREALLRRQRAFREAPGLIADGRDMGTIVFPDAPVKIFLDASSQERAHRRMLQLQERGFNVNFERLLAEIQERDNRDRNRSVAPLVPAADALVLDSTSMSIEQVIEQALAYAQRILALPLKK
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.