PharMolix/UniProtQA huggingface dataset:
Protein: LPXC_BRUMB
Sequence: MNAYQKTIGRAVTLSGVGIHGGAPASARLLPADADTGILFQRSDIKDSAPVCAHVSQIGATDLCTSLGAREARIDTVEHLMAAISALGIDNLVVEIEGPEVPILDGTSARFIEAVDSVGVVTQDAKRRFIRILKTVRVEAGNSWGEFRPYDGTRFEVEIDFECPLIGRQKFAHDVDEETFRKELSTARTFGFMKDVERLWAAGLALGASLDNSLVIGDDNSIVNADGLRFKDEFVRHKTLDAVGDLALAGLPFIGCFSSYRGGHRLNSEAVKALLSDETAFEIIEA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: NUOI_RICM5
Sequence: MINYLKSFFLYEIVRGMALTLKYFFKPKVTINYPYEKSPVSPRFKGEHALRRYENGEERCIACKLCEAICPAQAIVIEADEREDGSRRTTRYDIDMTKCIYCGLCQAACPVDAIVEGPNFEFASLTHTALIYDKERLLQNGDRWEQALASKLHKDYEYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MGT5B_HUMAN
Sequence: MITVNPDGKIMVRRCLVTLRPFRLFVLGIGFFTLCFLMTSLGGQFSARRLGDSPFTIRTEVMGGPESRGVLRKMSDLLELMVKRMDALARLENSSELHRAGGDLHFPADRMPPGAGLMERIQAIAQNVSDIAVKVDQILRHSLLLHSKVSEGRRDQCEAPSDPKFPDCSGKVEWMRARWTSDPCYAFFGVDGTECSFLIYLSEVEWFCPPLPWRNQTAAQRAPKPLPKVQAVFRSNLSHLLDLMGSGKESLIFMKKRTKRLTAQWALAAQRLAQKLGATQRDQKQILVHIGFLTEESGDVFSPRVLKGGPLGEMVQWADILTALYVLGHGLRVTVSLKELQSNLGVPPGRGSCPLTMPLPFDLIYTDYHGLQQMKRHMGLSFKKYRCRIRVIDTFGTEPAYNHEEYATLHGYRTNWGYWNLNPKQFMTMFPHTPDNSFMGFVSEELNETEKRLIKGGKASNMAVVYGKEASIWKLQGKEKFLGILNKYMEIHGTVYYESQRPPEVPAFVKNHGLLPQPEFQQLLRKAKLFIGFGFPYEGPAPLEAIANGCIFLQSRFSPPHSSLNHEFFRGKPTSREVFSQHPYAENFIGKPHVWTVDYNNSEEFEAAIKAIMRTQVDPYLPYEYTCEGMLERIHAYIQHQDFCRAPDPALPEAHAPQSPFVLAPNATHLEWARNTSLAPGAWPPAHALRAWLAVPGRACTDTCLDHGLICEPSFFPFLNSQDAFLKLQVPCDSTESEMNHLYPAFAQPGQECYLQKEPLLFSCAGSNTKYRRLCPCRDFRKGQVALCQGCL
What is the function of this protein?
Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans.  Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAc-beta1,2-Man-alpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan.  Also acts on the GlcNAc-beta1,2-Man-alpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan.  Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway.
What are the official names of this protein?
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B, Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase B, GlcNAc-T Vb, GNT-Vb, hGnTVb, Mannoside acetylglucosaminyltransferase 5B, N-acetylglucosaminyl-transferase Vb, N-acetylglucosaminyltransferase IX, GNT-IX.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 18 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: ISPDF_HYPNA
Sequence: MTETVAIIVAGGRGQRAGAERPKQWQMLLGKRVIDWSIAAFVDHPQISQVVIVAGDELGDCSAEPKIIQAKPGNTRTQSVLSGLAAATISEDATVVIHDAARPGIDAATISSLIARLQDPSVSGAAPAMPVADALKTNSGQSWTNVDRTGLVRVQTPQAFRLGEIRAALSAAGPDLVDDLTAIEAAGGRVEIVSGSARLTKITYPEDFDMLARLLSPTGAPRIGKGYDVHEFEAGDHVTLCGVAIPHIAKLKGHSDADAAWHALTDAILGAVALGDIGDHFPPSDPQWKGADSGLFLKEAQRLAEAKGYVIANCDITVICEAPKVKPHREAMRARTAELLGLPLDAVSVKATTTEGLGFTGRREGIAAEAVALLMPKG
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: RS13_NITHX
Sequence: MARIAGVNIPTNKRVVIALQYIHGIGQKNAAEIIDKVKIPADRRVSQLSDQEVLQIREVIDRDYLVEGDLRREVGINIKRLMDLGCYRGLRHRRGLPVRGQRTHTNARTRKGPAKSIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RSXB_SALPA
Sequence: MNTIWIAVGALTLLGLVFGAILGYASRRFAVEDDPVVEKIDAILPQSQCGQCGYPGCRPYAEAVGLQGEKINRCAPGGEAVMLKMAELLNVEPQPCDGEEQQAAPVRMLAVIDENNCIGCTKCIQACPVDAIVGATRAMHTVMSDLCTGCNLCVDPCPTHCIELRPVNETPDSWKWDLNTIPVRIIPVEQHA
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rsx electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: COAX_BORAP
Sequence: MNKPLLSELIIDIGNTSIAFASFKDNKINLFVKMKTNLMLRHDEVFSFFKENFDFNVNQVFISSVVPILNGIFENVIFSFFKIKPLFISFDLNYDLTFNPYKSGKFLLGSDVFANLVAAIENYSFENVLVVDLGTACTIFAVSRQDGILGGLINSGPLINFNSLLDNAYLLKKFSISTPSNLLERTTSGSVNSGLFYQYKYLIEGVYRDIKKMYKKEFNLIIAGGNANLLLPLIEIEFIFNIHLTVEGIRILGNSIVF
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CITG_ALBFT
Sequence: MPTATALRIDAGSGASDLGEAIGRLAERSLVLELELTPKPGLVDRANSGAHRDMDVGTFRASIAAISPWFSFFFERGVDGSAVPVEDFLRYIRADGMACERAMFAATLGVNTHKGSVFSFGLLCAAAGRLHGRGRPLSRASVCAEVSHICAGLVKRELLLPAAARTAGELLYWQHGLTGARGEAQSGFATACAHGVVPYLLARAKGMDEERSLFEALLQLMAHNRDTNIVSRGGMEGLCLVQAEARRLLDCPTPSRSARTAQLAAFDQLLIERNLSPGGSADLLAVSWFLANLDELVCKCVA
What are the official names of this protein?
Probable 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase, 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the CitG/MdcB family.
Protein: ASSY_HELMO
Sequence: MKGALGMSKKVVLAYSGGLDTSIIIPWLKENYGYEVIAMAADLGQGEELEPLNEKAINTGATKIYIEDVKEEFVTEFIWPTLKAGAVYEGKYLLGTSFARPLIAKRLVEIARKEGAEAIAHGATGKGNDQVRFELTVKALAPDLKIVAPWREWDIRSREDAIDYAQARNIPVPVKKDRPYSMDRNLWHLSHEGADLESPWNEPQNDLFMICTPPEQAPDKPEYVEIEFEKGIPVKLNGEALGPVEMIEKLNAIAAAHGVGICDMVENRLVGMKSRGVYETPAGTVLYAAHRELEYLCLDRATMHYKEMVALRYAELVYDGVWYHPLRKAIDAFVDVTQETVTGLVRMKLFKGSVTPAGAKSPYSLYNEEFSTFGRDEVYNQKDAEGFINLFGLPMKVRALMEQKSGLK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACSL1_MOUSE
Sequence: MEVHELFRYFRMPELIDIRQYVRTLPTNTLMGFGAFAALTTFWYATRPKALKPPCDLSMQSVEIAGTTDGIRRSAVLEDDKLLVYYYDDVRTMYDGFQRGIQVSNNGPCLGSRKPNQPYEWISYKEVAELAECIGSGLIQKGFKPCSEQFIGLFSQNRPEWVIVEQGCFSYSMVVVPLYDTLGADAITYIVNKAELSVIFADKPEKAKLLLEGVENKLTPCLKIIVIMDSYGSDLVERGKKCGVEIISLKALEDLGRVNRVKPKPPEPEDLAIICFTSGTTGNPKGAMITHQNIINDCSGFIKATESAFIASTDDVLISFLPLAHMFETVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQPTIFPVVPRLLNRMFDRIFGQANTSLKRWLLDFASKRKEAELRSGIVRNNSLWDKLIFHKIQSSLGGKVRLMITGAAPVSATVLTFLRTALGCQFYEGYGQTECTAGCCLSLPGDWTAGHVGAPMPCNYVKLVDVEEMNYLASKGEGEVCVKGANVFKGYLKDPARTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYLRSEAVAQVFVHGESLQAFLIAVVVPDVESLPSWAQKRGLQGSFEELCRNKDINKAILDDLLKLGKEAGLKPFEQVKGIAVHPELFSIDNGLLTPTLKAKRPELRNYFRSQIDELYATIKI
What is the function of this protein?
Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation (By similarity).  Preferentially uses palmitoleate, oleate and linoleate (By similarity).  Preferentially activates arachidonate than epoxyeicosatrienoic acids (EETs) or hydroxyeicosatrienoic acids (HETEs).
What are the official names of this protein?
Long-chain-fatty-acid--CoA ligase 1, Arachidonate--CoA ligase, Long-chain acyl-CoA synthetase 1, LACS 1, Phytanate--CoA ligase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Protein: HNRH1_HUMAN
Sequence: MMLGTEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGGAYGSQMMGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYDQVLQENSSDFQSNIA
What is the function of this protein?
This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm.  Mediates pre-mRNA alternative splicing regulation.  Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast.  Binds to the IR RNA.  Binds poly(RG).
What are the official names of this protein?
Heterogeneous nuclear ribonucleoprotein H, hnRNP H.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: THIM_ECO24
Sequence: MQVDLLSSAQSAHALHLFHQHSPLVHCMTNDVVQTFTANTLLVLGASPAMVIETEEASQFAAIASALLINVGTLTQLCAQSMCAAVEQAKSSQTPWTLDPVAVGALDYRRRFCLELLSHKPTAIRGNASEIMALAGIANGGRGVDTTDAAANAIPAAQTLARETGAIVVVTGEMDYVTDGHRIIGIHGGDPLMTKVVGTGCALSAVVAACCALPGDTLENVASACHWMKQAGERAVARSEGPGSFVPHFLDALWQLTQEVQA
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: COS12_YEAST
Sequence: MDGAKFENTVAFLPSEIFDCYNSTLPKNVFRSFVTWSCYEKFNSLEFRTWLLMWLPLIIAWKIRGKRHYLVIVTALMFEVLYFLWTYSYIFRERTLGKQVSQFAKEIITNTPGIDTEDWERVAVNFNSYLYENKLWNTEYFFFDGSSCQEAFRKMLLEPFSLKKNDFANAKVPDGSVCYTEKALQVYFTQIERKWHWINSEGFLHNKTTQSVQFSKHGYGSKLLWAFKEVTIMNSRFAFFSIAYLNGLLTIPRLRNSLHILYVCAVLSSMIIEYLIGIDKFRFKSMNLIHKLQFLSYITCGHEKSDATNWSQIAKRTNTYMFEQKIWNSPILFSDGIDCEKFFKWYFSTPVSSQASLSVGSTDFELWPYIKEAQSACNDV
What are the official names of this protein?
Protein COS12.
What is the protein family that this protein belongs to?
Belongs to the DUP/COS family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ZAT7_ARATH
Sequence: MVARSEEIVIVEEDTTAKCLMLLSRVGECGGGCGGDERVFRCKTCLKEFSSFQALGGHRASHKKLINSDNPSLLGSLSNKKTKTSHPCPICGVKFPMGQALGGHMRRHRNEKVSGSLVTRSFLPETTTVTALKKFSSGKRVACLDLDLDSMESLVNWKLELGRTISWS
What is the function of this protein?
Probable transcription factor involved in oxidative stress response.
What are the official names of this protein?
Zinc finger protein ZAT7.
What are the subcellular locations of this protein?
Nucleus.
Protein: LPXG_CHLMU
Sequence: MFVFVGSTVSLTAIVAAPVLTWIWANHLEPNLLKLTRLDWRLPKKFAHLHGLRIVQISDLHLNQSTPDAFLKKISRKVSSLSPDMLVFTGDFICRAKVESSNKLKNFLCSLNAPLGCFACLGNHDYATYVSRDIHGKINTIPETSSRPLRRALTSVYQSLFSSSHNEFAEEFTPQDPNPHLLSILHNTPFQLLHNQSVTLSDVVNIVGLGDFFAKQFDPKKAFTNYNPTLPGIILSHNPDTIHYLKDYPGDVVFSGHSHGPQISLPWPKFANTITNKLSGLENPELARGLFSFPQEKRLLYVNRGLGGWKRIRFFSPPEICIMRCLYEP
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to form 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipooligosaccharide (LOS) to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine pyrophosphatase LpxG, UDP-DAGn pyrophosphatase, UDP-2,3-diacylglucosamine hydrolase LpxG, UDP-DAGn hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: NU3M_HELAN
Sequence: MLEFAPICIYLVISLLVSLILLGVPFLFASNSSTYPEKLSAYECGFDPFGDARSRFDIRFYLVSILFIIFDLEVTFFFPWAVSLNKIDLFGFWSMMAFLLILTIGFLYEWKRGALDWE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: GATD_THEVO
Sequence: MQNVEIIYKNAKVRGILINEANGLITIKADNGYNLTFDRSEVEILSRVTIEEKKEKKTEVESFGTGEKSISILATGGTIASRVDYETGAVKPVSDPRLLFGGTELESKFNIRVVNVMNQLSENMKPADWIHLARKVMDETKHSSGIVVSHGTDTMSYTSSALAFMFERLAQPIIFVGSQRSSDRPSSDTKENMEGAINFAATDLGEVGIAMHKGISDGSIVLHRAVRSRKMHTSRRDAFESIDTVHLAEYTSSVRFFSDYRKAEEENLLLDHLDEKVSIIYFHPGLVASDVENMIEGKHAVVIMGTGLGHIAKDLIPVFKNFTKDGNFAIMTSQCIYGSVDMNVYSTGRELIAAGVISAGDMVPEVAYVKAMFTLGNYGREEFINVFNRNLRGEILNRLIPREVYI
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).  The GatDE system is specific for glutamate and does not act on aspartate.
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit D, Glu-ADT subunit D.
What is the protein family that this protein belongs to?
Belongs to the asparaginase 1 family. GatD subfamily.
Protein: LLDD_SHISS
Sequence: MIISAASDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSEVALRQRILKNMSDLSLETTLFNEKLSMPVALAPVGLCGMYARRGEVQAAKAADAHGIPFTLSTVSVCPIEEVAPAIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMRRYLQAVTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLGNNFDPSISWKDLEWIRDFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAFLYALATAGQAGVANLLNLIEKEMKVAMTLTGAKSISEITQDSLVQGLGKELPTALAPMAKGNAA
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CAPP_BURM9
Sequence: MKSSGSARATRRNAVSSSSAPAHAEPPARRAAKPARKLDGAAARPLAPTNAASAKPQGRTREDKDRPLFEDIRYLGRLLGDVVREQEGDAVFDVVETIRQTAVKFRREDDKAAAQTLEKMLRKLTPEQTVSVVRAFSYFSHLANIAEDRHHNRRRRIHALAGSAAQAGTVAYALDKLKQAGDASSKTIKQFFEGALIVPVLTAHPTEVQRKSILDAQHDIARLLAERDQPLTARELAHNEALLRARVTTLWQTRMLRDARLTVADEIENALSYYRATFLDELPALYADIEEALAEHGLRARVPAFFQMGSWIGGDRDGNPNVTAATLDEAISRQAAVIFEHYLEQVHKLGAELSVSNLLVGASDALKALAAASPDQSPHRVDEPYRRALIGVYTRLAASARVRLGEGTVPVRSAGRGAAPVRATPYADAEEFAADLRVLTDSLALHHGESLATPRLAPLMRAAEVFGFHLASIDLRQSSDIHEAVVAELLARGGVEADYAALPEADKLRVLLAALADPRPLRSPYLDYSDLAKSELGVLERAHAIRAQFGARAVRNYIISHTETVSDLVEVLLLQKETGLFEGTLGTPHANARNGLMVIPLFETIADLRNASDIMRAFFALPGVGELLAHQGHEQEVMLGYSDSNKDGGFLTSNWELYRAELALVDLFDERGIKLRLFHGRGGTVGRGGGPTYQAILSQPPGTVNGQIRLTEQGEVIASKFANPEIGRRNLETVVAATLEATLAPHSNAPKQLPAFEAAMQTLSDAAMASYRALVYETPGFTDYFFSSTPITEIAELNIGSRPASRKLQDPKNRKIEDLRAIPWGFSWGQCRLLLTGWYGFGSAVAAYLDGAPDAAERGKRVALLKKMNKTWPFFANLLSNMDMVLAKTDLAVASRYAQLVADKKLRKHVFERIVAEWHRTADALAEITGAHARLAANPLLARSIKNRFPYLDPLNHLQVELIKRHRAGDTNARLRRGIHLTINGIAAGLRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: ARGC_STRMK
Sequence: MNDSTFTLGIVGARGHTGAELIKLVAAHPRLELAFVSSRERAGQRLSDHHPEFQGELQYENLDADAVAAKGVDAVILALPNGLAAPFVAALEAAKPDTVIVDLSADYRFDNSWYYGLPELTRGRYNGQKHISNPGCYATAMQLAVHPLLDLLAGPPQCFGVSGYSGAGTTPSDKNNVELLADNLMPYALTNHVHEREVSVQLGVAVEFMPHVAPHFRGITLTANLWLNRVQTREQIVERFQQAYAGEPLIEVLDEAPWVSRIAGRHGAQVGGFTLAPGGKRVVVVATLDNLLKGAATQAMQNLNLALGIDELTSIPH
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_STRP2
Sequence: MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQAKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVFRKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGFSNAVNLTDGVDGLASISVVISLFAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKPAKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKRIFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LPXB_ESCF3
Sequence: MTEQRPLTIALVAGETSGDILGAGLIRALKERVPNARFVGVAGPRMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRADLTKRFGELKPDVFVGIDAPDFNITLEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRATDLVLAFLPFEKAFYDKYNVPCRFIGHTMADAMPLDPDKNAARDVLGIPHDAHCLALLPGSRGAEVEMLSADFLKTAQLLRQTYPDLEIVVPLVNAKRREQFERIKAEVAPDLSVHLLDGMGREAMVASDAALLASGTAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTEYVSLPNLLAGRELVKELLQEECEPQKLAAALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAAQAVLELAQ
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: Y1834_CALS4
Sequence: MRFVIITGLSGAGKTQALKAMEDMGFFCIDNFPPALIPKLADLFYQSKNIDKVALGMDLRGGQFFEDIYSSLDFLKKNNYDYEIVFLEASDEVLIKRFKETRRRHPLSEEGRIVDGINEERKRLSDIRKIANYIIDTSNLTSSQLKEELSNIFLKGKKFKGIIIDVMSFGYKYGIPLEADLVFDVRFLPNPFYIDELRPLTGNDEKVKEYVMKWEEAKEFLKKLGDMIKFLIPYYVREGKSQLVIAIGCTGGKHRSVAIANALYDLLKKEDYSVVVNHRDIGEE
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein TTE1834.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: CR3L3_RAT
Sequence: MDGDISTGKMASPACAMAPLDSMEVLDLLFDGQDGILRNVDLAESWILTREEQKVLPNSDSDEFLNSILGPGDSDPSSPIWSPADSDSGISEDLPSDSQDTPPGSGPGSANVAARCHPSKQGEGPCPSYLPSTACPEPPRTQVHESSVAIDLDMWSTDTLYPEEQAGSPSRFNLTVKELLLSGGGGDLQQHPLAASQLLGPGSGHCQELVLTEDEKKLLAKEGVTLPTQLPLTKYEERVLKKIRRKIRNKQSAQESRKKKKEYIDGLENRMSACTAQNQELQRKVLHLEKQNLSLLEQLKHLQALVVQSTSKPAHAGTCIAVLLLSFVLIILPSISPFTANKVDSPGDFIPVRVFSRTLHNHAASRVAPDVTPGPEVPGPHKGSSGGLSADWGNFLEIPMLDDPTEELDNTTLVLANSTEDLGRATLLDWVASEPLLGQMGLEIPGEEIWLSWVPRWLRVRVVQDALGVL
What is the function of this protein?
Transcription factor that may act during endoplasmic reticulum stress by activating unfolded protein response target genes.  Activated in response to cAMP stimulation.  Binds the cAMP response element (CRE).  Activates transcription through box-B element and CRE.  Seems to function synergistically with ATF6.  In acute inflammatory response, may activate expression of acute phase response (APR) genes (By similarity).  May be involved in growth suppression.  Regulates FGF21 transcription (By similarity).  Plays a crucial role in the regulation of triglyceride metabolism and is required for the maintenance of normal plasma triglyceride concentrations (By similarity).
What are the official names of this protein?
Cyclic AMP-responsive element-binding protein 3-like protein 3, cAMP-responsive element-binding protein 3-like protein 3, Transcription factor CREB-H.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. ATF subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Processed cyclic AMP-responsive element-binding protein 3-like protein 3]: Nucleus. Note=Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus.
Protein: FLGI_CHRSD
Sequence: MRSLLRWMGVLLLCGLCAAPAQAERIRDLASFAGVRENQLVGYGLVVGLDGTGDQTTQTPFTGQTLINMLSQLGVSIPEGTNMQLRNVAAVMVTAQLPPFARQGQEMDVTVSSMGNADSLRGGTLLMTPLRGVDGNVYAMAQGNLLIGGVGAQQAGSSVQVNHTAAGRIPGGATVEQEVALQLGRADGTLDLYLNESDFTTAQRVVEAINRDFGSPVAAAMDGRLIRLNAPSDSNSRVNFMARIQNLDVTPNQGPAKVIVNSRTGSVVLNREVTLDRAAVAHGNLSVTIDSNPQVSQPNPLGEGETVVVPDADISIQQEGGALQMVNTSADLMDVVNALNALGASPQDLMSILQALKSAGALNAELEII
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: Y1260_STRSY
Sequence: MSTNIYDIANELERAIRNLPEYKAVEAVKVSVEGNSEAKEILESYISFQKEIQSKLQAGEIPTEADQKKMLDFNKKVQGNPLLTEYFSKQQQLGTYVADLERIIFKPLNELL
What are the official names of this protein?
UPF0342 protein SSU05_1260.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.