PharMolix/UniProtQA huggingface dataset:
Protein: CCKN_HUMAN
Sequence: MNSGVCLCVLMAVLAAGALTQPVPPADPAGSGLQRAEEAPRRQLRVSQRTDGESRAHLGALLARYIQQARKAPSGRMSIVKNLQNLDPSHRISDRDYMGWMDFGRRSAEEYEYPS
What is the function of this protein?
This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut.  Its function in the brain is not clear.  Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion.
What are the official names of this protein?
Cholecystokinin, CCK.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL27_SHISS
Sequence: MAHKKAGGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGANVGCGRDHTLFAKADGKVKFEVKGPKNRKFISIEAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: KATG_PECCP
Sequence: MDENKTKPAGKCPVMHGGNTATGSSNTDWWPNALNLDILHQHDTKTNPLGSDFSYRDALKTLDVDALKKDLHALMTDSQEWWPADWGHYGGLMIRMAWHSAGTYRTADGRGGGGTGNQRFAPLNSWPDNVSLDKARRLLWPIKKKYGNKLSWADLIILAGNIAYESMGLKTFGFAFGREDIWHPEKDIYWGSEKEWLAKSTGRYGSDDRTTLENPLAAVQMGLIYVNPEGVDGNPDPLRTAQDMRVTFSRMAMNDEETVALTAGGHTVGKTHGNGDASLLGKAPEGTDVGEQGLGWHNPTGSGKGRYTVTSGLEGAWTTHPTQWDNGFFHMLLNHEWELKKSPAGAWQWEPVFIKEEDKPVDVEDPSIRYNPMMTDADMALKVDPEYRKISERFYQDQAYFSEVFARAWFKLTHRDMGPKTRYLGPDVPQEDLLWQDPVPAGRTDYDVDVVKARIAESSLSISELVATAWDSARTFRGSDMRGGANGARIRLAPQKDWVGNEPERLARVLVVLENIAAATGASVADTIVLAGNVGIEKAAKAAGVNITVPFAPGRGDTTDALTDVESFDVLEPIHDGYRNWLKKDYAVSPEELMLDRTQLMGLTAKEMTVLVGGLRVLGTNYGGTKHGVFTDREGALTNDFFANLTDMKYTWKPYRKDLYEIRDRKTGEVKWTATRLDLVFGSNSILRSYAEVYAQDDNKEKFVNDFVAAWVKVMNADRFDLAE
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: THII_CLOBA
Sequence: MEKLILVKYAPEIFLKGLNRNKFEKRLRDNIGKKLEGIKIEFIHDSGRYFIKTNEINESIKRLSNVFGVSEVAVVDVVEIDMDSIKKSSLEKLIEAEGKTFKVSTNRANKNFEGNSTDISRDIGAYILSNYNDEMNVDVKTPDILINVEIRNKNAYVWSNKDITKGVAGLPYGMNGSTMLMLSGGIDSPVAGYLMAKRGVELNCVYYHSHPYTSERAKDKVKDLAKILASYTEKINLYVVPFTEIQMAILDKCREDELTIIMRRFMMRVACKIAEEKGIQSVTSGESIGQVASQTMEGLIVSNDCADRPVFRPLIAMDKTDIMDIARKIETYETSILPYEDCCTIFVPKHPKTKPRVDSIREEEKKLNIDELVRKAIDEMENIVY
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTLD_SHISS
Sequence: MKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARHSYQVHVVGETEQVDTVSGVNAVSSIGDDVVDLIAQVDLVTTAVGPVVLERIAPAIAKGLVKRKEQGNESPLNIIACENMVRGTTQLKGHVMNALPEDAKAWVEEHVGFVDSAVDRIVPPSASATNDPLEVTVETFSEWIVDKTQFKGALPNIPGMELTDNLMAFVERKLFTLNTGHAITAYLGKLAGHQTIRDAILDEKIRAVVKGAMEESGAVLIKRYGFDADKHAAYIQKILGRFENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYSLPHKNLIQGIAGAMHFRSEDDPQAQELAALIADKGPQAALAQISDLDANSEVVSEAVTAYKAMQ
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: COPA_STAAC
Sequence: MANTKKTTLDITGMTCAACSNRIEKKLNKLDDVNAQVNLTTEKATVEYNPDQHDVQEFINTIQHLGYGVAVETVELDITGMTCAACSSRIEKVLNKMDGVQNATVNLTTEQAKVDYYPEETDADKLVTRIQKLGYDASIKDNNKDQTSRKAEALQHKLIKLIISAVLSLPLLMLMFVHLFNMHIPALFTNPWFQFILATPVQFIIGWQFYVGAYKNLRNGGANMDVLVAVGTSAAYFYSIYEMVRWLNGSTTQPHLYFETSAVLITLILFGKYLEARAKSQTTNALGELLSLQAKEARILKDGNEVMIPLNEVHVGDTLIVKPGEKIPVDGKIIKGMTAIDESMLTGESIPVEKNVDDTVIGSTMNKNGTITMTATKVGGDTALANIIKVVEEAQSSKAPIQRLADIISGYFVPIVVGIALLTFIVWITLVTPGTFEPALVASISVLVIACPCALGLATPTSIMVGTGRAAENGILFKGGEFVERTHQIDTIVLDKTGTITNGRPVVTDYHGDNQTLQLLATAEKDSEHPLAEAIVNYAKEKQLILTETTTFKAVPGHGIEATIDHHHILVGNRKLMADNDISLPKHISDDLTHYERDGKTAMLIAVNYSLTGIIAVADTVKDHAKDAIKQLHDMGIEVAMLTGDNKNTAQAIAKQVGIDTVIADILPEEKAAQIAKLQQQGKKVAMVGDGVNDAPALVKADIGIAIGTGTEVAIEAADITILGGDLMLIPKAIYASKATIRNIRQNLFWAFGYNIAGIPIAALGLLAPWVAGAAMALSSVSVVTNALRLKKMRLEPRRKDA
What is the function of this protein?
Involved in copper export.
What are the official names of this protein?
Copper-exporting P-type ATPase, Copper-exporting P-type ATPase A, Cu(+)-exporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RCEL_RHOCA
Sequence: MALLSFERKYRVPGGTLIGGSLFDFWVGPFYVGFFGVTTIFFATLGFLLILWGAAMQGTWNPQLISIFPPPVENGLNVAALDKGGLWQVITVCATGAFCSWALREVEICRKLGIGFHIPVAFSMAIFAYLTLVVIRPMMMGSWGYAFPYGIWTHLDWVSNTGYTYGNFHYNPFHMLGISLFFTTAWALAMHGALVLSAANPVKGKTMRTPDHEDTYFRDLMGYSVGTLGIHRLGLLLALNAVFWSACCMLVSGTIYFDLWSDWWYWWVNMPFWADMAGGING
What is the function of this protein?
The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.
What are the official names of this protein?
Reaction center protein L chain, Photosynthetic reaction center L subunit.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular chromatophore membrane; Multi-pass membrane protein.
Protein: RSSA_CAEEL
Sequence: MSGGAAHSALTEEDVMKLLATQAHLGSTNLNFQMQQYVYKRRFDGPNIINVKKTWEKLLLAARAIAAVENPADVVVVSARPYAQRALLKFAAHTGATAIFGRFSPGCLTNQIQKTFKEPRLLVISDPRIDHQAVTEASYVGVPVISFVNTESPLKLIDIGVPCNNKGERSIGLMWWMLAREILILRGKISRQTGFVLEGKEIMPDLYFYRDPTETEKEETGAHADVAEAQEYQQPTDIDFTTQGGKVDDWAAETATWTAETKTTEEWANAPTQSNW
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein SA.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOD_MYXXA
Sequence: MPTQKPSKASVKPTKKKVDPVIRKKKAPDGAAAKGAKTGAEEKEELVARDVVAEATEKLKKKKKGVAPAMGDDVDPEEAAEEAAAAVQVDPDAVEDDIEEDPVAERKEVKDLLAAGREKGFLTYDEVNDALPADIVSSDQIDDVMSMFGDNDIEIVDAQKAAQNNEIKPTVTVEEEKEDADEDEKDEDDEPGGKSNDPVRLYLRKMGSVSLLTREGEVEIAKRIEDGEKEVLRALLACKVAVEEILDIGNKLKTAKLRVRDVIKDAPEETQSEGAEEAPEEVGEGDAPAQLAQSELNKIEQICKQIERFRKFAQDCDVLEEELSSKKKLTEVRKKEVKQEIKDLRTKMMEVLEEMRLNKKQVDRIVINLKALIERVDKAEDELRDLERRYDCSMKELRPQLKESRENPNIGKKLQKQLNLTPEQLEVLDRDVRTAVRKIKKVEEEANLPVESLRRNYDAIRLGERRAERAKSELVEANLRLVVSIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYKRGYKFSTYATWWIRQAITRAIADQARTIRIPVHMIETINKLIRTSRYLVQEIGREPTPEEIAEKMELPLDKVRKVLKIAKEPISLETPIGEEEDSHLGDFIEDKSLVSPADAVINMNLAEQTRKVLATLTPREEKVLRMRFGIGEKSDHTLEEVGQDFEVTRERIRQIEAKALRKLRHPSRSKRLRSFVES
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is the primary sigma factor during exponential growth (By similarity).  Also required for extracellular A-signal production.  The A-signal is the first in a series of extracellular signals that are required for myxspore differentiation in M. xanthus.  It is thought to act as a cell-density signal during early development to ensure there are enough cells present to complete fruiting-body morphogenesis.  A variant at residue 598 prevents A-signal production in an unknown fashion.
What are the official names of this protein?
RNA polymerase sigma factor RpoD, Sigma-80.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2581_STAAM
Sequence: METLELQGAKLRYHQVGQGPVLIFIPGANGTGNIFLPLAEQLKDHFTVVAVDRRDYGESELTEPLPDSASNPDSDYRVKRDAQDIAELAKSLSDEPVYILGSSSGSIVAMHVLKDYPEVVKKIAFHEPPINTFLPDSTYWKDKNDDIVHQILTEGLEKGMKTFGETLNIAPIDAKMMSQPADTEEGRIEQYKRTMFWSEFEIRQYTHSDITLDDFTKYSDKITLLNGTDSRGSFPQDVNFYINKETGIPIVDIPGGHLGYIQKPEGFADVLLNMWG
What are the official names of this protein?
Uncharacterized hydrolase SAV2581.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: ANMK_SALEP
Sequence: MKSGRFIGVMSGTSLDGVDVVLAAIDETMVAQQASLTWPIPVHLKKGILDICQGQPLTLSQLGQLDTQLGRLFAQAVNALLARQRLQPRDIVAIGCHGQTVWHEPTGEAPHTLQIGDNNHIVAHTGITVVGDFRRRDIALGGQGAPLVPAFHHALLGHPTEKRMVLNIGGIANLSLLFPGQAVRGYDTGPGNMLMDAWIWRQCAQPYDKDAAWAKEGQVILPLLQKMLRDPYFAASAPKSTGREYFNYGWLERHLTAFPGADARDVQATLAELTAVSIAQQVLLNGGCERLMVCGGGSRNPLVMARLAALLPGIEVSTTDKAGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGATEASVLGAIYPANPITQS
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: RL22_CERS4
Sequence: MGKEKNPRRVGENEAFAKVKMLRTSPQKLNLVAALIRGKKVDKAIADLTFSKKRISQDVLKCLQSAIANAENNHGLDVDELVVSEAFCGKNLVMKRGRPRARGRFGKIMKPFSELTIKVKQVGETA
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: MTGA_PSEP1
Sequence: MLSTLIRRLSRALLWFVAGSIVLVLVFRWVPPPGTALMVERKVQSWVNGEPIDLQRDWEPWENISDELKVAVIAGEDQKFANHWGFDLPAIQAALAHNERGGNIRGASTLTQQVAKNLFLWSGRSWFRKGLEAWFTALIELFWSKERILEVYLNSAEWGKGVFGAQAAARYHFGVDASRLSRQQAAQLAAVLPSPIKWSASRPSAYVASRAGWIRRQMSQLGGPSYLMQLDSSRKL
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: S29A3_RAT
Sequence: MAFASEDIAYHSSNAVYRVPSNRHEADQEALLGKPLDYPAPGLQRPEDRFNGAYIIFFCLGIGGLLPWNFFVTAKEYWAFKLRNCSSPASGKDPEDADILNYFESYLAVASTVPSLLFLVANFLLVNRIRVHVRVLASLSVSLAIFVVMAVLVRVDTSSWTRGFFSIAMACMAIISSSSTIFNSSVYGLTGSFPMRNAQALISGGAMGGTVSAVASLVDLAASSDVRDSALAFFLTAAVFLGLCVGLYLLLPQLEYARYYMRPVVPIHVFSSEDSPPRDAPSTSSVAPASRAVHTPPLGPILKKTAGLGFCAVFLYFITALIFPAISTNIQPMHKGTGSPWTSKFYVPLTVFLLFNFADLCGRQVTAWIQVPGPRSKLLPILAVSRVCLVPLFLLCNYQPRSHLTLVLFQSDIYPILFTCLLGLSNGYLSTLVLMYGPKIVPRELAEATSVVMLFYMSLGLMLGSACAALLEHFI
What is the function of this protein?
Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter).  Mediates transport of adenine, adenosine and uridine (By similarity).
What are the official names of this protein?
Equilibrative nucleoside transporter 3, Solute carrier family 29 member 3.
What is the protein family that this protein belongs to?
Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Late endosome membrane. Lysosome membrane. Note=Intracellular localization shows a partial overlap with late endosomes/lysosomes. Not detected at the cell surface (By similarity).
Protein: GATC_HUMAN
Sequence: MWSRLVWLGLRAPLGGRQGFTSKADPQGSGRITAAVIEHLERLALVDFGSREAVARLEKAIAFADRLRAVDTDGVEPMESVLEDRCLYLRSDNVVEGNCADELLQNSHRVVEEYFVAPPGNISLPKLDEQEPFPHS
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial, Glu-AdT subunit C, Protein 15E1.2.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YFCN_SHIDS
Sequence: MKKKTTLSEEDQALFRQLMAGTRKIKQDTIVHRPQSKKISEVPVKRLIQEQADASHYFSDEFQPLLNTEGPVKYVRPDVSHFEAKKLRRGDYSPELFLDLHGLTQLQAKQELGALIAACRREHVFCACVMHGHGKHILKQQTPLWLAQHPHVMAFHQAPKEYGGDAALLVLIEVEEWLPPELP
What are the official names of this protein?
UPF0115 protein YfcN.
What is the protein family that this protein belongs to?
Belongs to the UPF0115 family.
Protein: SIR2_DANRE
Sequence: MSEEVSKRVEEEADTPGLEGQSDDSSDEGDASGDTEMDFLRSLFSRTLGLSPGDKVLDELTLDSVARYILSGKCKNIICMVGAGISTSAGIPDFRSPGTGLYANLQKYNLPYPEAIFQIDYFKKHPEPFFALARELYPGQFKPTVYHYFIKMLKDKGLLRRCYSQNIDTLERVAGLEGEDLIEAHGTFHTSHCVSFLCRKEYSMDWMKNQIFSEEIPKCDSCGSLVKPDIVFFGESLPSRFFTSMKADFPQCDLLIIMGTSLQVQPFASLVSRVSNRCPRLLINMEKTGQSEFGMGLFSFGGGMDFDSDKAYRDVAHLSTCDDGCMTLAELLGWKKELEEMVKREHALIDSKDAKKTDKEASQSSKSAVAEAEKTDKTE
What is the function of this protein?
NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and alpha-tubulin as well as many other proteins such as key transcription factors (By similarity).  Participates in the modulation of multiple and diverse biological processes such as cell cycle control, genomic integrity, microtubule dynamics, cell differentiation, metabolic networks, and autophagy.  Plays a major role in the control of cell cycle progression and genomic stability.  Deacetylates histone H4 at 'Lys-16' (H4K16ac) at the VEGFA promoter (PubMed:24940000).  Thereby contributes to regulate expression of vegfa, a key regulator of angiogenesis (PubMed:24940000).  In addition to protein deacetylase activity, also has activity toward long-chain fatty acyl groups and mediates protein-lysine demyristoylation and depalmitoylation of target proteins (By similarity).
What are the official names of this protein?
NAD-dependent protein deacetylase sirtuin-2, NAD-dependent protein defatty-acylase sirtuin-2, Regulatory protein SIR2 homolog 2, SIR2-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: 5HT2A_CRIGR
Sequence: MEILCEDNTSLSSIPNSLMQVDGDSGLYRNDFNSRDANSSDASNWTIDGENRTNLSFEGYLPPTCLSILHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGVSMPIPVFGLQDDSKVFKQGSCLLADDNFVLIGSFVAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEHVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPALAYKSSQLQAGQNKDSKEDAEPTDNDCSMVTLGKQQSEETCTDNINTVNEKVSCV
What is the function of this protein?
G-protein coupled receptor for 5-hydroxytryptamine (serotonin).  Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD).  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors.  Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways.  Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores.  Affects neural activity, perception, cognition and mood.  Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances.  Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction (By similarity).
What are the official names of this protein?
5-hydroxytryptamine receptor 2A, 5-HT-2, 5-HT-2A, Serotonin receptor 2A.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, axon. Cytoplasmic vesicle. Membrane, caveola. Cell projection, dendrite. Presynapse.
Protein: TOX5_BORPE
Sequence: MQRQAGLPLKANPMHTIASILLSVLGIYSPADVAGLPTHLYKNFTVQELALKLKGKNQEFCLTAFMSGRSLVRACLSDAGHEHDTWFDTMLGFAISAYALKSRIALTVEDSPYPGTPGDLLELQICPLNGYCE
What is the function of this protein?
PTX oligomer B binds to receptors on the eukaryotic cell surface and facilitates the translocation of the toxic subunit across the cell membrane.
What are the official names of this protein?
Pertussis toxin subunit 5, PTX S5, Islet-activating protein S5, IAP S5.
What are the subcellular locations of this protein?
Secreted. Host cell membrane.
Protein: RL5_STRPJ
Sequence: MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEAVSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLDKLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTTANTDEESRALLTGLGMPFAK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: GLGC_LACLA
Sequence: MAIEMLGLILAGGQGTRLGKLTKDVAKPAVPFGGRYRIIDFALSNCANSNVKNVGVITQYQPLTLNAHIGNGAPWGLNGINSGVTILQPYSSQEGSKWFEGTSHAVYQNISYIDQQNPEYVLILSGDHIYKMDYEAMLESHKEREASLTVSVMEVPLEEASRFGIMNTDDNDRIIEFEEKPKEPKSNLASMGIYIFNWKRLREVLVNGYSKGNPMEDFGGDVIPAYIEAGENVFAYRFKGYWKDVGTIDSLHQSSMEFLDLNNELNITDKSWRIYSHNDISAPQFITEKSNVKNALVGDGCYVDGTVLHSILSQNVHVQEGTVIEDSFIMSGTFIGENVTIKNAIIGENAKIGDNVEIIGENEVAVIGHGEIKGENKNEQ
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: RL16_ACTP2
Sequence: MLQPKRTKFRKVHKGRNRGIAGGTEVSFGTFGLKAVGRCRLTARQIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLEVRMGKGKGNVEYWVALIQPGKVLYEMDGVSEEIARHAFALAAAKLPVKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: ISPG_RALSO
Sequence: MQMTTPVDCAPALPGPLPRRHSRAAEIRWGERLVRVGGDAPVCVQSMTNTDTADAIGTAIQVKELARTGSELVRITVNTPEAAAAVPAIREQLDRMGIDVPLVGDFHYNGHKLLQDHPACAEALSKYRINPGNVGQGAKRDTQFAQMIETACRYGKPVRIGVNWGSLDQDLLARIMDENAQRAAPWDARAVMIEALITSAIESARKAEEIGLPGSQIILSCKVSAVQDLIAVYRELARRCDYALHLGLTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGAPREKEVIVAQEILQTMGLRNFTPMVIACPGCGRTTSTVFQELAARIQSYLREQMPVWKTQYPGVEDMNVAVMGCIVNGPGESKHANIGISLPGTGESPAAPVFVDGVKVKTLRGERIAEDFQVIVDEYVRTHYGAAQAKATAAE
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: PYRB_LEUMM
Sequence: MRNYLNINAINKNDVLHLIQRALALKSGEQPKTKSITAVNLFFENSTRTHSSFQMAENQLNWKQIQIDPQTSSMTKGESLVDTLKTLKAIGVDVAVIRHSQNSWYENVLRSEGHAIPQLVNAGDGSGQHPSQSLLDLVTIYQEFGHFEGLKVRIIGDLAHSRVARSNAEILNKLGATVTFSGPKDWQPVDFDSFGEHVDLDVGWSEQDVVMFLRVQHERITHTENQNFSAKKYHEVYGLTESRYENLKENSIIMHPAPVNRDVEIADDLVEAPKSRIFDQMTNGVYARMAILEYVTE
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: FAEB1_ASPFC
Sequence: MMWWFLLIGLASAAATASSASSASFESRCQHFHKEIHLQNVHVLSTTYVPIGSNIPMVYNPPICGGTASSSISTIQFCQVALNVTTSDKSQFFMEAWLPSNYTGRFLSTGNGGLNGCVSYADMVYATQYGFATIGTNNGHFGDTGQYFLNNPEVIEDFAYRALHTGTVVGKALTKLFYPQGYKNSYYLGCSTGGRQGWKSIQRFPDDFDGVVAGAPAINFVNLCSWGSRFLKITGPPGSETFVTSAQWSAVHNEILRQCDALDGAVDGIIEDTDLCQPVFETLLCNSTAVDKTSCLTGVQANTVNEVFSAMYGLDGKWLYPRMQPGSELAASFIYYSGNGFKYSDDWYKYVVYNDSNWDHSTWTLADAAAAAAQDPFQISSFDGNISGFQKAGGKVLHYHGLEDAIITSDSSKAYYKHVADTMGLSPSELDHFYRLFPISGMGHCSPGTGAASIGQGSSTYAGDDPQDNVLMAIVQWVEKGIAPEYVRGSKMSRDGTIDYRRKHCKYPKRNRYVGPGKYTDENAWKCV
What is the function of this protein?
Involved in degradation of plant cell walls.  Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans as well as the feruloyl-galactose and feruloyl-arabinose ester bonds in pectin.
What are the official names of this protein?
Probable feruloyl esterase B-1, Ferulic acid esterase B-1, FAEB-1.
What is the protein family that this protein belongs to?
Belongs to the tannase family.
What are the subcellular locations of this protein?
Secreted.
Protein: PRTE_DICCH
Sequence: MTGMDITTQDELNEAAMRDRASRDEERALRLGWWLVLAGFGGFLLWALLAPLDKGVAVQGNVVVSGNRKVIQHMQGGIVDRIQVKDGDRVAAGQVLLTLNAVDARTTSEGLGSQYDQLIAREARLLAEQRNQSSLAATPRLTQARQRPEMAAIIALQEDLLRSRQQSLKLEIDGVRASIDGLETSLGALQKVMSSKQSEQATLSQQLQGLRPLAADNYVPRNKMLETERLFAQVSGELAQTSGEVGRTRRDIQQQKLRIAQRQQEYDKEVNSELSDVQAKLNEVISQREKADFNLANVQVRAPVAGTVVDMKIFTEGGVIAPGQVMMDIVPEDQPLLVDGRIPVEMVDKVWSGLPVELQFTAFSQSTTPRVPGTVTLLSADRLVDEKDGTPYYGLRIQVSEEGKRSLHGLEIKPGMPVQGFVRTGERSFINYLFKPLMDRMHLALTEE
What is the function of this protein?
Involved in the secretion of proteases A, B, C and G.
What are the official names of this protein?
Proteases secretion protein PrtE.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: GCSH_OCEIH
Sequence: MSLPQDLLYSKEHEWVKQEDGKLRIGITDFAQDELGDIVFVELPEIGEELKVDDPFGSVESVKTVSELYAPVSGKVVEINDDLEDSPEYVNESPYEKAWMIVIEPSDEKELEELLSAENYEAFIQD
What is the function of this protein?
Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
What are the official names of this protein?
Glycine cleavage system H protein, Octanoyl/lipoyl carrier protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.