PharMolix/UniProtQA huggingface dataset:
Protein: BICRL_MOUSE
Sequence: MDDDDDSCLLDLIGDPQALNYFLHGPSSKSGSDDVTNAGYSAANSNSIFANSTNADPKSALKGVSDQLGEGPSDGLPLASSLQFLEDELESSPLPDLSEDQPFDILQKSLQEANITEQTLAEEAYLDASIGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTHVPVGASFASNTVGVQHGFMQHVGISVPSQHLPNSSQISGSGQIQLIGSFGNQPSMMTINNLDGSQIILKGSGQQAPSNVSGGLLVHRQTPNGNSLFGNSTSSPVAQPVTVPFNSTNFQASLPVHNIIIQRGLAPNSNKVPINIQPKPVQMGQQSAYNVNNLGIQQHHAQQGISFAPTSSPQGSVVGPHMSVNIVNQQNTRKPVTSQAVSGTGGSIVIHSPMGQPHTPQSQFLIPTSLSVSSNSVHHVQAINGQLLQTQPSQLISGQVASEHVMLNRNSSNMLRTNQPYSGQMLNNQNTAVQLVSGQTFATSGSPVIVNHASPQIVGGQMPLQQASPTVLHLSPGQSSVSQGRPGFATMPAVSGMAGPARFPAVSSASTAHPTLGPTVQSGAPGSNFTGDQLTQANRTPAPVSVSHRLPVSASKSPSTLSNTPGTQQQFFCQAQKKCLNQTSPIPTSKTTDGLRPSQIPGLLSTALPGQDSGSKIMPATLGATQAQPESSVGSSPSQTAVQVDSHPGQKRPAAKQLTKGAFILQQLQRDQAHAVTPDKSQFRSLNDTVQRLLSYHVCQGSMPTEEDLRQVDNEFEEVATQLLKRTQAMLNKYRFLLLEDAMRINPSAEMVMIDRMFNQEERASLSRDKRLALVDPEGFQADFCCSFKLDEAVPETPLDRSDQHRSKTSSLHQVPRAQSRDRAKPGMAEATNHDQFHLVPNHIVVSAEGNISKKSEGHSRTLKFDRGVLGQYRGPPEDKGGRRDPAKVSRCSPGPEGHRKSLPRPDHGSESKLPGVLASSHMEMPCLDSFQDKALRNSPKNEVLHTDIMKGSGEPQPDLQLTKSLEKTFKNILELKNSGRPPSDPTASGAADLDFPSFSPMASQENCLEKFIPDHSEGVVETDSILEAAVNSILEC
What is the function of this protein?
Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner.
What are the official names of this protein?
BRD4-interacting chromatin-remodeling complex-associated protein-like.
Protein: RK33_ORYNI
Sequence: MAKGKDVRIRVILQCVSCVRKGANEESAGISRYSTQKNRHNTPGQLELRKFCRYCRKHTIHAEIKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: 3SB2_HEMHA
Sequence: LKCHNKVVPFLSKTCPEGKNLCYKMTLKKVPKIPIKRGCTDACPKSSLLVNVMCCKTDKCN
What is the function of this protein?
This protein lyses red blood cells, has cytotoxic activity and induces hypotension, but is not neurotoxic.  In addition, it induces direct paralysis of the muscle fiber.
What are the official names of this protein?
Cytotoxin 2, Toxin 12A.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IB cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ZN136_PONAB
Sequence: MDSVAFEDVDVNFTQEEWALLDPSQKNLYRDVMWETMRNLASVGKKWKDQNIKDHYKHRGRNLRSHMLERLYQTKDSSQRGGIFSQFANQNLSKKIPGVKLCESIVYGEVSMGQSSLNRHIKDHSGHEPKKYQEYGEKPDTRNQCWKPFSSHHSFRTHEIIHTGEKLYDCKECGKTFFSLKRIRRHIITHSGYTPYKCKVCGKAFDYPSRFRTHERSHTGEKPYECKECGKAFTCITSVRRHMIKHTGDGPYKCKVCGKPFHSLSSFQVHERIHTGEKPFKCKQCGKAFSCSPTLRIHERTHTGEKPYECKQCGKAFSYLPSLRLHERIHTGEKPFVCKQCGKAFRSASTFQIHERTHTGEKPYECKECGEAFSCIPSMRRHMIKHTGEGPYKCKVCGKPFHSLSPFRVHERTHTGEKPYVCKHCGKAFVSSTSIRIHERTHTGEKPYECKQCGKAFSYLNSFRTHEMIHTGEKPFECKRCGKAFRSSSSFRLHERTHTGQKPYHCKECGKAYSCRASFQRHMLTHAEDGPPYKCMWESL
What is the function of this protein?
May be involved in transcriptional regulation as a weak repressor when alone, or a potent one when fused with a heterologous protein containing a KRAB B-domain.
What are the official names of this protein?
Zinc finger protein 136.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MSHR_ALLNI
Sequence: MPVQGSQRRLLGSLNSTPTATPHLGLAANQTGAWCLEVSIPDGLFLSLGLVSLVENVLVVTAIAKNRNLHSPMYCFICCLALSDLLVSGSNMLETAVTLLLEAGALAARAAVVQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVLFSMLFIAYYDHAAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPAHQGFGLKGAATLTILLGIFFLCWGPFFLHLTLIVLCPQHPTCSCIFKNFNLFLALIICNAIIDPLIYAFRSQELRRTLKEVLLCSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PHUZ_BP201
Sequence: MPVKVCLIFAGGTGMNVATKLVDLGEAVHCFDTCDKNVVDVHRSVNVTLTKGTRGAGGNRKVILPLVRPQIPALMDTIPEADFYIVCYSLGGGSGSVLGPLITGQLADRKASFVSFVVGAMESTDNLGNDIDTMKTLEAIAVNKHLPIVVNYVPNTQGRSYESINDEIAEKIRKVVLLVNQNHGRLDVHDVANWVRFTDKHNYLIPQVCELHIETTRKDAENVPEAISQLSLYLDPSKEVAFGTPIYRKVGIMKVDDLDVTDDQIHFVINSVGVVEIMKTITDSKLEMTRQQSKFTQRNPIIDADDNVDEDGMVV
What is the function of this protein?
A tubulin-like GTPase that forms filaments, which are required for positioning viral DNA and capsids in the middle of the host cell for optimal replication (PubMed:28082593, PubMed:22726436, PubMed:25429514, PubMed:31199917, PubMed:28813669).  The motor component of a partition system which pushes phage DNA (encased by protein gp105) to the center of the bacterial host cell (PubMed:28082593, PubMed:28813669).  Also required for movement of phage capsids to the vicinity of the viral DNA and rotation of the encased viral DNA at midcell (PubMed:31199917).  Forms filaments during the lytic phase, which position phage DNA at the center of the bacterial host cell (PubMed:22726436, PubMed:25429514, PubMed:31199917, PubMed:28082593, PubMed:28813669).  Filaments have a three-stranded intertwined achitecture and form a spindle-like cytoskeleton within the infected cell (PubMed:24631461).  Has GTPase activity (PubMed:22726436).  Filaments grow at the plus end and depolymerize at the minus end, a process called treadmilling, and switch from growing in a polar manner to catastrophic depolymerization, i. e.  they display dynamic instability, like tubulin.  In infected host cells the filament ends close to the cell pole are relatively stable, while the other end near the phage DNA is highly dynamic (PubMed:25429514).  Both capsid movement and DNA rotation probably require treadmilling (Probable).
What are the official names of this protein?
Phage tubulin-like protein, PhuZ, Phage tubulin/FtsZ, Tubulin-like protein TubZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family. PhuZ subfamily.
What are the subcellular locations of this protein?
Host cytoplasm. Note=In infected host cells forms a spindle-like structure emanating from each cell pole.
Protein: PAPA2_MYCBO
Sequence: MFSITTLRDWTPDPGSIICWHASPTAKAKARQAPISEVPPSYQQAQHLRRYRDHVARGLDMSRLMIFTWDLPGRCNIRAMNYAINAHLRRHDTYHSWFEFDNAEHIVRHTIADPADIEVVQAEHQNMTSAELRHHIATPQPLQWDCFLFGIIQSDDHFTFYASIAHLCVDPMIVGVLFIEIHMMYSALVGGDPPIELPPAGRYDDHCVRQYADTAALTLDSARVRRWVEFAANNDGTLPHFPLPLGDLSVPHTGKLLTETLMDEQQGERFEAACVAAGARFSGGVFACAALAERELTNCETFDVVTTTDTRRTPTELRTTGWFTGLVPITVPVASGLFDSAARVAQISFDSGKDLATVPFDRVLELARPETGLRPPRPGNFVMSFLDASIAPLSTVANSDLNFRIYDEGRVSHQVSMWVNRYQHQTTVTVLFPDNPIASESVANYIAAMKSIYIRTADGTLAILKPGT
What is the function of this protein?
Required for the biosynthesis of sulfolipid-1 (SL-1), a major mycobacterial cell wall lipid.  Catalyzes the acylation of trehalose-2-sulfate by adding the palmitoyl group at the 2'-position to yield the intermediate trehalose-2-sulfate-2'-palmitate (SL659).
What are the official names of this protein?
Trehalose-2-sulfate acyltransferase PapA2, 2-O-sulfo trehalose long-chain-acyltransferase, Polyketide synthase-associated protein A2.
What is the protein family that this protein belongs to?
Belongs to the PapA acyltransferase family.
Protein: ATG9_ASHGO
Sequence: MEQSEDTIQHERKNTFLSRVFGVHSSEVGDSIETAELSQYPIQIARSGSNAIDESRVIESDQASSSEEEDTDGHDLSVAENMTSYNGAQGSGSEDSDVPFSDQELETIETYTIAKVGQGSSSEDDRLQADSAEEEDALLFQHRLQDGSKGRNKVSSQPLGLKRILGSKGKSILGKEPASQEDSFIFRKGPTWDEENQLRPESKRPGLLSGKSNARLSSPSRPSPLSARERALWKWANVENLDGFLQDVYSYYLGNGFYCIMIEKILNLLTLLFIVFISTYMSHCIDYSKLPNGHKFSDVRVDQCYETQITGTTKLLFWIFGVFVVLKVVQMYFDFRRIHEIHNFYTYLLNISDKELQTIPWQSVIHQIMRLKDQNAVTANVVEVKAKNHIDAHDVANRIMRKENYLIALYNKDILHLSLPIPLYRTSTLTKTLEWNIHLCIIGFAFNEAGFLKQSFLNPAQREFLSEELKKRFILAGFLNIILAPFLVVYFVLLYFFRYFNEYKTSPGSLSTRQYTPIAEWKFREYNELYHLFKKRMGLSYEVANTYINQFPNALGDYFFKFVKFISGSFVAILALMTVLDPENFLNFELTADRTVLFYMTVLGTIWAVCHSAVNDNCSVFDPEDSLKELITYIHYAPKEWDGRYHTDEVKQEFCKLYNLRVILLLRELASLIMTPFILWFSLPNSAESIVDFFREVTVYGDGLGYVCKYAMFDENCKKGLRTNKHLQGTQTKYGHSLGDDHDSSDEETDKGMNKMIQSYMYFVDDYQNSVNAVGKYQIPKTQNLSHESKYNMKSHQHYSWKKQFKLGSKPEDFKIGSVTPRALSSSILANKPKSNLRARLDPEISHSNVQFDDLGESFINSIPVADYDPIERSDAMGGNGVLGLLNQYYRKSDVGR
What is the function of this protein?
Phospholipid scramblase involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation.  Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome.  Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.  Required for mitophagy.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.
What are the official names of this protein?
Autophagy-related protein 9.
What is the protein family that this protein belongs to?
Belongs to the ATG9 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: YTFP_ECOL6
Sequence: MRIFVYGSLRHKQGNSHWMTNAQLLGDFSIDNYQLYSLGHYPGAVPGNGTVHGEVYRIDNATLAELDALRTRGGEYARQLIQTPYGSAWMYVYQRPVDGLKLIESGDWLDRDK
What are the official names of this protein?
Gamma-glutamylcyclotransferase family protein YtfP.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamylcyclotransferase family.
Protein: MNTP_YERE8
Sequence: MNLSATLVLAFAMSMDAFAASIGKGASLHKPRFREAIRTGLIFGVIEAITPLIGWCIGLFASQYILEWDHWIAFSLLFILGCRMIFEGAKQQVEETEKMRSHSFWVLVMTAIATSLDAMAIGVGLAFLQVNIVHTAMAIGLATMIMATLGMLIGRYIGPLLGKRAEIIGGIVLIGIGFNILYEHIYRLA
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RM36_YEAST
Sequence: MLKSIFAKRFASTGSYPGSTRITLPRRPAKKIQLGKSRPAIYHQFNVKMELSDGSVVIRRSQYPKGEIRLIQDQRNNPLWNPSRDDLVVVDANSGGSLDRFNKRYSSLFSVDSTTPNSSSETVELSEENKKKTQIKKEEKEDVSEKAFGMDDYLSLLDDSEQQIKSGKLASKKRDKK
What is the function of this protein?
Overexpression suppresses mutations in the COX2 leader peptide-encoding and initiation codon regions.
What are the official names of this protein?
54S ribosomal protein L36, mitochondrial, Mitochondrial large ribosomal subunit protein bL31m, YmL36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Highly divergent.
What are the subcellular locations of this protein?
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Protein: MODD_HAEIN
Sequence: MIYFSDKELDDLLLEDIYRGDLTTHALSIENIPAKILFKRKNAGVVAGVSVAEKLLKKLDIQPHLYVKEGEWVESGALLISAEGMSEQLHQAWKVVQLVLEWSCGVAQYTAEMIANAKSVNPTAVVACTRKSIPNTRKLATNAVLAAGGHIHRQGVSETLLVFTNHRNLLSDPNDWTKIVDRLRQEAPENKITLEADNYAQFEQMYMAEPDIIQLDKWLLEDVKKALDLLQSKQKDILLSVAGGVNKNNVSDYAKLGIRLFITSAPYYVPPEDIKVVIEKI
What are the official names of this protein?
Putative pyrophosphorylase ModD.
What is the protein family that this protein belongs to?
Belongs to the NadC/ModD family.
Protein: GDL16_ARATH
Sequence: MASLDSHVLMKLGSLFLSTLFVSIVSSESQCRNFESIISFGDSIADTGNLLGLSDHNNLPMSAFPPYGETFFHHPTGRFSDGRLIIDFIAEFLGLPYVPPYFGSTNGNFEKGVNFAVASATALESSFLEEKGYHCPHNFSLGVQLKIFKQSLPNLCGLPSDCRDMIGNALILMGEIGANDYNFPFFQLRPLDEVKELVPLVISTISSAITELIGMGGRTFLVPGGFPLGCSVAFLTLHQTSNMEEYDPLTGCLKWLNKFGEYHSEQLQEELNRLRKLNPHVNIIYADYYNASLRLGREPSKYGFINRHLSACCGVGGPYNFNLSRSCGSVGVEACSDPSKYVAWDGLHMTEAAHKSMADGLVKGPYAIPPFDWSCLSSMIKKKEVVGNTIFFDE
What are the official names of this protein?
GDSL esterase/lipase At1g31550, Extracellular lipase At1g31550.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: PFA5_KLULA
Sequence: MAWSLGTLRVTSHPYFRLLIPFLTVLLQCYGVWAFCHQFCYLQLYQRRNAKGACIGLIIVVLSLTFLIWYIWALMLVLGPGRQPTIPPFKIIPDSEIRTVSSESAVPDNSIAPPDIYPCDERGYPIWCSNCQSLKMSRTHHSTKVGYCVPRFDHYCVWIGTVLGRLNYKLFVQFTFYLDLVVLILMISIATQMRQMKGSANGNVYAVFALACCALLMAGPLFLTHIYYMCYNRTSIEIIEVNNKAKASRKFFCIYNPCDGYRYVIQFCPGENQDFWNKGNILTNLKEFLGPNYLSWFIPSILTHKQSYGKSSANYYDLIGDCNEVMSEKFQKYMIDKIERKEYVTRLVV
What are the official names of this protein?
Palmitoyltransferase PFA5, Protein fatty acyltransferase 5.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. PFA5 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MUKB_ENT38
Sequence: MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSVLDVINSRHQRVVVGVRLQQVAGRDRKVDIKPFAIQGLPTSVQPTAMLTETLNDRQARVLSLQELKEKLEEIEGVQFKQFNSITDYHSLMFDLGIVARRLRSASDRSKYYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATNYVAADYMRHANERRIHLDKALEYRRELFTSRKQLVAEQYKHVEMARELGEQNGAEGDLEADYQAASDHLNLVQTALRQQEKIERYESDLDELQIRLEEQNEVVAEATEMQEENEARAEAAELEVDELKNQLADYQQALDVQQTRAIQYTQALQALQRAKELCHLPDLTPESADEWLETFQAKQQEATDKLLSLDQKMSVAQTAHSQFEQAYQLVTAINGPLARSDAWEVARELLRDGVNQRHLAEQVQPLRMRLNELEQRLREQQEAERLLAEFCKRYGKRVDIDDLEALHQELEARIASLSDSVSNAGEQRMSLRQELEQLQSRTQKLLQRAPVWLAAQSSLNQLSEQCGEEFESSQDVTEYLQQLLEREREAIVERDEVGARKRAIDEEIERLSQPGGAEDSRLNALAERFGGVLLSEIYDDVSLDDAPYFSALYGPSRNAIVVPDLSLIADQLEGLEDCPEDLYLIEGDPQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPTLPLFGRAARENRIESLHAERETLSERFATLSFDVQKTQRLHQSFSRFIGSHVAVAFEPDPEAEIRKLNTRRGELERAISLHENDNQQSRVQFEQAKEGVAALNRILPRLNLLADETLADRVDEIQERLDEAQEAARFVQQHGNQLAKLEPVLSVLQSDPEQFEQLKEDYAYSQQVQRDARQQAFALAEVVQRRAHFGYSDSAEMLSGNSDLNEKLRHRLEQAETERSRTRDALRSHAAQLSQYGQVLASLKSSFDTKKELLTDLQKELQDIGVRADSGAEERARIRRDELHSQLSNNRSRRNQLEKALTLCEAEMDNLTRRLRKLERDYHEMREQVVTAKAGWCAVMRLVKDSGVERRLHRRELAYLSGDELRSMSDKALGALRPAVADNEHLRDVLRMSEDPKRPERKIQFFVAVYQHLRERIRQDIIRTDDPVEAIEQMEIELGRLTEELTSREQTLAISSRSVANIIRKTIQREQNRIRMLNQGLQSVSFGQVNSVRLNVNVLEAHATLLDVLSEQHEQHQDLFNSNRLTFSEALAKLYQRLNPQIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSILVMVVQSWEDESRRLRGKDISPCRLLFLDEAARLDARSIATLFELCDRLGMQLIIAAPENISPEKGTTYKLVRKVFQNTEHVHVVGLRGFAPQPPESLPEAADAS
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: GCNK_GLUOX
Sequence: MTEHETQMGLKPRFLVVMGVSGTGKTTVATGLATRLGWHFQEGDALHPPANVEKMSTGQPLTDADRAPWLALCHDWLREQVKAGHGAVLTCSALKRSYREQLRGDDLPIEFVHIDTSTGELADRLQRREGHFMPASLLPSQLATLEVPGDDEPVIRVSGEKHPDVVLEELIRHFQAED
What is the function of this protein?
Phosphorylates gluconate to 6-phosphogluconate.
What are the official names of this protein?
Gluconokinase, Gluconate kinase.
What is the protein family that this protein belongs to?
Belongs to the gluconokinase GntK/GntV family.
Protein: COBS_SYNFM
Sequence: MWSHFGTALSFLTLFRLPFTSPRTLTPQELAESFSFFPLVGLILGFCYALPARVLSGVVPSLLLAVAITALTAVLTRALHLDGLADLADGVGGGYDPERRLEIMKDSRTGAFGALAIALAVAFKVAALDAVIRAGSFLPLLLVPVVSRLAMVLAAYRSPYARKEGGLGKPFLEHIARRHLLTALGLTAVSAFLVQPVFGLCALVLAAGTVPAFRLLCRRWLGGMTGDALGALNEIVEVLLLSAAACMY
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1998_MYCTU
Sequence: MSFHDLHHQGVPFVLPNAWDVPSALAYLAEGFTAIGTTSFGVSSSGGHPDGHRATRGANIALAAALAPLQCYVSVDIEDGYSDEPDAIADYVAQLSTAGINIEDSSAEKLIDPALAAAKIVAIKQRNPEVFVNARVDTYWLRQHADTTSTIQRALRYVDAGADGVFVPLANDPDELAELTRNIPCPVNTLPVPGLTIADLGELGVARVSTGSVPYSAGLYAAAHAARAVSDGEQLPRSVPYAELQARLVDYENRTSTT
What are the official names of this protein?
Uncharacterized protein Rv1998c.
Protein: PGLR1_ASPAC
Sequence: MHLNTTLLVSLALGAASVLASPAPPAITAPPTAEEIAKRATTCTFSGSNGASSASKSKTSCSTIVLSNVAVPSGTTLDLTKLNDGTHVIFSGETTFGYKEWSGPLISVSGSDLTITGASGHSINGDGSRWWDGEGGNGGKTKPKFFAAHSLTNSVISGLKIVNSPVQVFSVAGSDYLTLKDITIDNSDGDDNGGHNTDAFDIGTSTYVTISGATVYNQDDCVAVNSGENIYFSGGYCSGGHGLSIGSVGGRSDNTVKNVTFVDSTIINSDNGVRIKTNIDTTGSVSDVTYKDITLTSIAKYGIVVQQNYGDTSSTPTTGVPITDFVLDNVHGSVVSSGTNILISCGSGSCSDWTWTDVSVSGGKTSSKCTNVPSGASC
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.  Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall.
What are the official names of this protein?
Endopolygalacturonase I, Pectinase 1, Polygalacturonase I, PG-I.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PP4C_HUMAN
Sequence: MAEISDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPSKKPVADYFL
What is the function of this protein?
Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration.  The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3.  The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphorylated on Ser-140 (gamma-H2AX) generated during DNA replication and required for DNA double strand break repair.  Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity).  In response to DNA damage, catalyzes RPA2 dephosphorylation, an essential step for DNA repair since it allows the efficient RPA2-mediated recruitment of RAD51 to chromatin.
What are the official names of this protein?
Serine/threonine-protein phosphatase 4 catalytic subunit, PP4C, Pp4, Protein phosphatase X, PP-X.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-4 (PP-X) subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: G7P_BPF1
Sequence: MEQVADFDTIYQAMIQISVVLCFALGIIAGGQR
What is the function of this protein?
May initiate with G9P the virion concomitant assembly-budding process, by interacting with the packaging signal of the viral genome.  The assembly-budding takes place at the host inner membrane.  In turn, G7P and G9P are present at the end of the filamentous virion that emerges first from the bacterial host (By similarity).
What are the official names of this protein?
Tail virion protein G7P, Coat protein C, polypeptide I, Gene 7 protein, G7P.
What is the protein family that this protein belongs to?
Belongs to the inovirus G7P protein family.
What are the subcellular locations of this protein?
Virion. Host membrane; Single-pass membrane protein. Note=Prior to assembly, is found associated with the bacterial host inner membrane. There are about five copies of this protein per mature phage that are located on the tail side of the filamentous virion with G9P (By similarity).
Protein: MSHA1_CATAD
Sequence: MTARRGSAPHRIATISVLTSPLAQPGGGDAGGLNVYVVETARRFAETGVQVDIFTRAAAPRLPPIVELCDGVVVRHVPAGPPREVDKGALPRVLGEFTAGMLRAPGDYDVVHAHHWLSGRVGALVARSRGVPLVQSMHSLGLVKNAVLPGEDGSAPPAQIAGESAVIAAADRLVANTAQEADQLIALYGAAPERVHTVHPGVDLELFRPGDRDQARARLGLPHDAFVLLFAGRVQRLKGPDILMRAAAQLLHADLDLAQRLVVAFVGGPSGELQADPDQLTKLATDLGIGEQVRVEPPCPHPELADWYRAATLVVVPSRAETFGLVAVEAQACGTPVVAAAVGGLQTAVRAGVSGVLVEGHDPARYAEVIRALIDDPARLTALRAGALQHAAGFGWSEAVDRLLAVYRSAIEGGRGRP
What is the function of this protein?
Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
What are the official names of this protein?
D-inositol 3-phosphate glycosyltransferase 1, N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase 1, GlcNAc-Ins-P N-acetylglucosaminyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. MshA subfamily.
Protein: RTF2_MOUSE
Sequence: MGCDGGTIPKRHELVKGPKKVEKVDKDAELVAQWNYCTLSQEILRRPIVACELGRLYNKDAVIEFLLDKSAEKALGKAASHIRSIKNVTELRLSDNPAWEGDKGNTKGDKHDDLQRARFICPVVGLEMNGRHRFCFLRCCGCVFSERALKEIKAEVCHTCGAAFQEEDIIVLNGTKEDVEMLKKRMEERRLRAKLEKKTKKPKTATECASKPGTTQDSAGPSKVKSGKPEEADPDPREKKSTPAPRGAATNGSASGKVGKPPCGALKRSIADSEESETYKSIFTSHSSAKRSKEESAHWVTHTSYCF
What is the function of this protein?
Replication termination factor which is a component of the elongating replisome.  Required for ATR pathway signaling upon DNA damage and has a positive activity during DNA replication.  Might function to facilitate fork pausing at replication fork barriers like the rDNA.  May be globally required to stimulate ATR signaling after the fork stalls or encounters a lesion.  Interacts with nascent DNA.
What are the official names of this protein?
Replication termination factor 2, RTF2, Replication termination factor 2 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the rtf2 family.
What are the subcellular locations of this protein?
Chromosome. Note=Localizes at the replication fork.
Protein: RIBBA_PORG3
Sequence: MEEIKLNTIEEALEDFKEGKFLIVVDDEDRENEGDFIIAAEKITPDKVNFMMHHGRGVLCAPISEERAHELELEMQVPDNTSVHETPFTVTVDRLGNGCTTGVSMYDRAQTILALADPNTRPSDLGRPGHICPLRARSRGVLRRAGHTEAAVDLARLCGMQPAAALIEIINEDGTMARLPQLWEVSKRFGLKIIAIKDLIAYRLKQESIVEKGVEVDMPTEYGHFRLIPFRQKSNGLEHIALFKGTWDENEPILVRMHSSCATGDIFGSMRCDCGGQLLQAMEKIEKEGKGAIIYLNQEGRGIGLMEKMKAYKLQEQGMDTIDANLCLGHKADERDYGIGAQILRLLGIKKMRLMTNNPVKRIGLEAFGLEIVENIPLETAPNRYNEFYLRTKKERMGHELHNIK
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: MYOT2_SCHGR
Sequence: TSSLFPHPRL
What are the official names of this protein?
Myotropin-2, Scg-MT-2.