PharMolix/UniProtQA huggingface dataset:
Protein: PP2AA_CHICK
Sequence: MEEKSFAKELDQWIEQLNECRQLSESQVRSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL
What is the function of this protein?
PP2A is the major phosphatase for microtubule-associated proteins (MAPs).  PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, PP2A-alpha.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle pole. Note=In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles.
Protein: Y967_YERPN
Sequence: MFGKGGIGNLMKQAQQMQEKMQQMQEEVAKLEVTGESGAGLVKVTINGAHNCRRVEIDPSLLVEDDKEMLEDLIAAALNDAARRIDETQKEKMASVSNGMQLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein YPN_0967.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: NAPA_RALPJ
Sequence: MKVSRRAFIKQTAAAATASVAGVTLPAGAANLVTDKELTQLKWSKAPCRFCGTGCGVEVAVKDNRVVATQGDPKAEVNRGLNCVKGYFLSKIMYGKDRLTQPLLRMKNGKYDKNGEFTPVTWDRAFDEMAMQFKRVIKEKGPTAVGMFGSGQWTVFEGYAAVKLMKAGFRSNNLDPNARHCMASAVAGFMRTFGMDEPMGCYDDFEVADAFVLWGSNMAEMHPILWSRVTDRRLSAPKTKVAVLSTFTHRSFDLADIPIVFTPQADLAMLNYIANYIITNKKVNTDFVNKHTVFKQGVTDIGYGLRPDNPVQKAAKNADKVGDSKPISFDEFAKFVSTYDLDYTTKLANPDKSKEKEFKQQLQKLAELYADPKIKVVSFWTMGFNQHTRGTWANNMIYNLHLLTGKIATPGNSPFSLTGQPSACGTAREVGTFSHRLPADMVVTNPKHREEAEHIWKLPAGTIPEKPGYHAVLQNRMLKDGKLNAYWVQVNNNMQAGANINEEGYPGYRNPANFIVVSDVYPTVTALAADLILPSAMWVEKEGAYGNAERRTQFWHQLVDAPGEARSDLWQLVEFSKRFKVEEVWPEDLIAKKPELRGKTLYDVLYRNGNVDRFPLKDVDPEYNNAEAKAFGFYLQKGLFEEYASFGRGHGHDLAPFDDYHKARGLRWPVVNGKETRWRYKEGSDPYVKAGTGYQFYGNPDGKAVIFALPYEAPPEVPDKEYPFWLSTGRVLEHWHSGSMTRRVPELYRAFPNAVCFMHPEDANALGLRRGVEVEVISRRGKMRTRIETRGRNQPPKGLVFVPWFDASQLINKVTLDATCPISLQTDFKKCAVKIVKV
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: FEMX_STAS1
Sequence: MEKMNITDQAHDAFVKAHPQGDLLQLTQWAETKTLTGWYSRRIAVGEDDEIVGVAQLLFKKVPKLPYTLCYISRGFVTDYSNKLALETLLEAAMQIAKEEKAYAIKIDPDVEVDKGADALSNLRALGFKHKGFKEGLSKDYIQPRMTMITPIEKTDVALIQSFERRNRSKVRLALKRGTTVERSNREGLKTFANLMQITGERDGFLTRDISYFENIYDALHPDGDAELFLVKLEPKPVLEDLRQELHELEDEKAKLADKKQDKKTLNKINDADNKIAKTQELIDEMVTLESTHPEGIYLSGALLMFAGKKSYYLYGASSNEYRNFLPNHHMQFAMMQYAREHGATSYDFGGTDNNPDKDSDHYGLWTFKKVWGTYLSEKIGEFDYVLNAPLYQIIENIKPKLTKAKIKLSRKLKK
What is the function of this protein?
Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor.
What are the official names of this protein?
Lipid II:glycine glycyltransferase, Factor essential for expression of methicillin resistance X.
What is the protein family that this protein belongs to?
Belongs to the FemABX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_EXISA
Sequence: MTGQLVQYGRHRQRRSFARISEVLELPNLIEIQTASYEWFLREGLKEMFTDISPISDFTGNLVLEFIDYSLSEPKYSIDESKERDVTYSAPLRVKVRLQNKETGELKEQEVFMGDFPLMTESGTFIINGAERVIVSQLVRSPSVYYNAKLDKNGKRGFGATVIPNRGAWLELETDAKDIVYVRIDRTRKIPVTVLLRALGFGTDQEIIDLLGDDEYLRNTLEKDNTESTEKALIEIYERLRPGEPPTVENAKSLLVSRFFDPKRYDLANVGRYKMNKKLHLKNRLFGQKLAETLVDPETGEVLAEAGTILDRRNLDRILPHLENGLGYIDAEPTGGVAEGEPFGLQSIKVISPDDPDGERILNIIGNGNIDRSVKHITPADIIASINYFFNLLHEVGTTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVKERMSIQDQNAITPQALINIRPVIASLKEFFGSSQLSQFMDQTNPLAELTHKRRLSALGPGGLTRERAGFEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNEYGFIEAPYRRVDPETGLVTGDIQYMTADEEDLYVVAQANMPLTEDGHFADEQVLCRFRGQNLSVEPSRVDYMDVSPKQVVSAATACIPFLENDDSNRALMGANMQRQAVPLLQPDSPIVGTGMEYVSAKDSGAAIVAKHPGVVERVTAREILIRRTSDVNGSEVSGDLDRYKLQKYVRSNQGTCYNQKPIIAAGDRVEKGEILADGPSMDMGELALGRNVVVAFMTWDGYNYEDAIIMSERLVKDDVYTSIHIEEYESESRDTKLGPEEITRDIPNVGDDALRNLDDRGIIRIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPNGGDGIILDVKVFDRENGDELSPGVNQMVRVYIVQKRKIHEGDKMAGRHGNKGVISRILPEEDMPYMPDGTPVDIMLNPLGVPSRMNIGQVLELHLGMAAKKLGIKVATPVFDGAREEDVWATIEEAGMDKDAKTRLYDGRTGEPFDNRVSVGVMYMIKLAHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTIKSDDTVGRVKAYEAIVKGESVPKAGVPESFRVLIKELQALGMEVKMMSADDEEVEMKDEDDDNIPNATSALEQVVQPTVTEEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: RL34_NOVAD
Sequence: MKRTFQPSRLVRARRHGFRARTATVGGRKVLAARRARGRKKLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RS4_CARHZ
Sequence: MARYTGPVCKLCRREGIKLFLKGDRCYTDKCAIARRNYAPGQHGHTRKKPTEYALQLREKQKAKRIYGVLEAQFRRYFEMAERQPGITGENLLVILERRLDNVVYRLGLAESRAQARQLVRHNFFTVNGRKVNIPSYLVKVGDVIALKEEKKDSPIAKEIMERAASKTLPAWLSYDANNAVGKVEALPKREDIDIPVEEHLIVELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RL27_KARMG
Sequence: MAHKKGVGSSRNGRDSFSKRLGVKLFGGQIAKPGSIIIRQRGTKHHPKKNVYMGKDHTIHSLIYGKILFKKTNKKKSFISVIPI
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: CREB3_HUMAN
Sequence: MELELDAGDQDLLAFLLEESGDLGTAPDEAVRAPLDWALPLSEVPSDWEVDDLLCSLLSPPASLNILSSSNPCLVHHDHTYSLPRETVSMDLESESCRKEGTQMTPQHMEELAEQEIARLVLTDEEKSLLEKEGLILPETLPLTKTEEQILKRVRRKIRNKRSAQESRRKKKVYVGGLESRVLKYTAQNMELQNKVQLLEEQNLSLLDQLRKLQAMVIEISNKTSSSSTCILVLLVSFCLLLVPAMYSSDTRGSLPAEHGVLSRQLRALPSEDPYQLELPALQSEVPKDSTHQWLDGSDCVLQAPGNTSCLLHYMPQAPSAEPPLEWPFPDLFSEPLCRGPILPLQANLTRKGGWLPTGSPSVILQDRYSG
What is the function of this protein?
(Microbial infection) It's transcriptional activity is inhibited by CREBZF in a HCFC1-dependent manner, by the viral transactivator HCV core protein.
What are the official names of this protein?
Cyclic AMP-responsive element-binding protein 3, CREB-3, cAMP-responsive element-binding protein 3, Leucine zipper protein, Luman, Transcription factor LZIP-alpha.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. ATF subfamily.
What are the subcellular locations of this protein?
[Isoform 1]: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus. Note=Colocalizes with HCFC1 in neuronal cell bodies of the trigeminal ganglia (PubMed:10623756). Colocalizes with DCSTAMP in the ER membrane of immature dendritic cell (DC) (PubMed:20546900). Colocalizes with CANX, CCR1, HCFC1 in the ER membrane (PubMed:10623756). SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasm. Note=(Microbial infection) Sequestered into the cytoplasm by the HCV core protein. SUBCELLULAR LOCATION: [Isoform 2]: Nucleus. Cytoplasm. Note=Predominantly in the nucleus (PubMed:19779205). Not associated with membranes (PubMed:19779205). SUBCELLULAR LOCATION: [Processed cyclic AMP-responsive element-binding protein 3]: Nucleus. Note=Upon RIP activation the transcriptional active processed cyclic AMP-responsive element-binding protein 3 form translocates into the nucleus. Detected in the nucleus upon dendritic cell maturation and RIP activation. Colocalizes with CREBRF in nuclear foci. Colocalizes with CREBZF in promyelocytic leukemia protein nuclear bodies (PML-NB).
Protein: OTC_LIMRJ
Sequence: MAFNLRNRSFLTLADFNTREMEYMLDLAEDLKKAKYAGYEGKNLKGKNIALIFEKSSTRTRCSFEVGAKDEGAHVTYLGPSGSHIGHKESVKDTARVLGGMFDGIEYRGFSQRNVEILAKYSGVPVWNGLTDEDHPTQVLADFLTAHEVLKKPYKDIKFAFVGDGQDNVSNALMLGAAVMGMEYHVVTPKELEPTKETLDKANEIAAKTGAKIVVTNDIKEGVKGMDVIYADVWVSMGESDDMWEKRINLLKPYQVTMDVMKATENPNVLFEHCLPAFHNLDTEVGKEIEKKFGLKEMEVTDEVFESEHSVVFREAENRMHTIKAVMVATLGEQN
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VM3_BUNMU
Sequence: MIQALLVTICLAVFPYQGSSIILESGNVNDYEVVYPQKVPLLPKGGVQNPQPKTKYEDTVQYEFEVNGEPVVLHLERNKGLFSEDYTEAHYAPDGREITTRPPVQDHCYYHGYIQNEADSSAAISACDGLKGHFKHQGETYFIEPLKLSDSEAHAIYKDENVEEENETPKICGLTETTWESDEPIRNASLLIYTPEQNRYLKVKKYIEFYVAVDNRMYRHYKRNKPIIKRRVYELVNILNTILRRLNFHIALIGLEIWSKRDKINVQSDVKATLKSFGKWREKKLLPRKRNDNAQLLTRIDFNGNTVGLAALGSLCSVKYSVAVIQDYSKRTSMVASTMAHEMGHNLGINHDRASCTSCGSNKCIMATKRTKPASRFSSCSVREHQRYLLRDRPQCILNKPLITDIVAPAICGNYFVEVGEECDCGSPRDCRSACCNAATCKLKHEAQCDSGECCGKCKFKKVGAKCRAAKDDCDLPERCTGRSAECPTDIFRRNGLPCQNKQGYCYNGKCPTLTNQCIALMGPNVKVSRDSCFTLNQRGKGCGYCRMQNGAKIPCAAKDIKCGKLFCKKRNSGVCNCLILPDDPNYGMVETGTKCGDGMVCSDRKCVKLQTVY
What is the function of this protein?
Snake venom zinc metalloproteinase that inhibits platelet aggregation and degrades fibrinogen.
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like BmMP, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SPEA_XYLF2
Sequence: MTWSQDLAHKTYSIRHWADGYFEVNDAGHMVVMPLGGDGVRISLPEVVDAARAAGAKLPLLLRFPDILGHRLGKLQAAFAQAQSEWEYAGGYTAVYPIKVNQHRGVAGVLASHQGDGFGLEAGSKPELMAVLALSRPGGLIVCNGYKDREYIRLALIGRKLGLKTFIVIEKPSELRMVLEEAKTLDVLPGLGVRVRLASLGAGKWQNSGGDKAKFGLSPRQVLDVWKVLRGTEYADCLNVMHFHMGSQISNVRDIAKGMREATRYFVELSRLGAKITHVDVGGGLGIDYEGTRSRSDCSINYGLQAYASHIVQPLASACEDYDLVPPRIVTECGRAMTAHHAVLIANVTEVEAVPEGRVPGVCDDEPAVVRHMREIYGELDARPAIELFYEAQHFHAEGLAAYTLGQIDLVHRARIDDLFYAISHGVRERLSHEEKSHRPVLDELNERLVDKYFVNFSVFESIPDVWAINQIFPIVPIERLNEVPTRRGVVCDLTCDSDGTVKQYVENESLDSALPLHVLRHGEAYRIGFFLVGAYQEILGDIHNLFGDTDAVEVAVDGRGYRIAQQRCGDTTDVMLDYVGYALDEVRRVYAQRIAAAGMSAAESKALSDMLEAGLTGYPYLSDVPLE
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: EFTU_UREPA
Sequence: MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAISTVLAKKGQAIAQSYADVDKTPEERERGITINASHVEYETKTRHYAHVDCPGHADYVKNMITGAAQMDGAILVIAASDGVMAQTKEHILLARQVGVPKIVVFLNKCDFMTDPDMQDLVEMEVRELLSKYGFDGDNTPVIRGSGLKALEGDPVWEAKIDELMDAVDSWIPLPERSTDKPFLLAIEDVFTISGRGTVVTGRVERGVLKVNDEVEIVGLKDTQKTVVTGIEMFRKSLDQAEAGDNAGILLRGIKKEDVERGQVLVKPGSIKPHRTFTAKVYILKKEEGGRHTPIVSGYRPQFYFRTTDVTGAISLPAGVDLVMPGDDVEMTVELIAPVAIEDGSKFSIREGGKTVGHGSVIKTSN
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG036_MONPV
Sequence: MTSSAMDNNESKVLEMVYDATILPDCSGMDPSIIDCINRHINMRIQRSYSSNIIAILDRFLMMNKDELNNTQCHIIKEFMTYEQMAIDYYGGYVNAILYQIRKRPNQHHTIDLFKRIKRTRYDTFKVNPVEFVKKVIGFVSILNKYKPIYSYVLYENVLYDELKCFIDYVETKYFQN
What is the function of this protein?
Plays a role in the inhibition of host innate immune response.  Within the host nucleus, inhibits activation of interferon-beta promoter by inhibiting IRF3 activation.
What are the official names of this protein?
Protein OPG036.
What is the protein family that this protein belongs to?
Belongs to the poxviridae OPG036 family.
Protein: CASPE_HUMAN
Sequence: MSNPRSLEEEKYDMSGARLALILCVTKAREGSEEDLDALEHMFRQLRFESTMKRDPTAEQFQEELEKFQQAIDSREDPVSCAFVVLMAHGREGFLKGEDGEMVKLENLFEALNNKNCQALRAKPKVYIIQACRGEQRDPGETVGGDEIVMVIKDSPQTIPTYTDALHVYSTVEGYIAYRHDQKGSCFIQTLVDVFTKRKGHILELLTEVTRRMAEAELVQEGKARKTNPEIQSTLRKRLYLQ
What is the function of this protein?
Non-apoptotic caspase involved in epidermal differentiation.  Is the predominant caspase in epidermal stratum corneum (PubMed:15556625).  Seems to play a role in keratinocyte differentiation and is required for cornification.  Regulates maturation of the epidermis by proteolytically processing filaggrin (By similarity).  In vitro has a preference for the substrate [WY]-X-X-D motif and is active on the synthetic caspase substrate WEHD-ACF (PubMed:16854378, PubMed:19960512).  Involved in processing of prosaposin in the epidermis (By similarity).  May be involved in retinal pigment epithelium cell barrier function (PubMed:25121097).  Involved in DNA degradation in differentiated keratinocytes probably by cleaving DFFA/ICAD leading to liberation of DFFB/CAD (PubMed:24743736).
What are the official names of this protein?
Caspase-14, CASP-14.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RUVB_STAEQ
Sequence: MDKRMVDQEFHNEDTDLELSLRPTQLKQYIGQSSIKSNLEVFIKAAKLRQEPLDHVLLFGPPGLGKTTLSNIIANEMEVNIRTISGPSLERPGDLAAILSGLQPGDVLFIDEIHRLSSVVEEVLYPAMEDFFLDIIIGKGDEARSIRIDLPPFTLVGATTRAGSLTGPLRDRFGVHLRLEYYNENDLKEIITRTAEVLGTDIDKESALELARRSRGTPRIANRLLKRVRDFQQVNEDDQIYIETTKRALQLLQVDQHGLDYIDHKMMNCIINQYNGGPVGLDTIAVSIGEERVTIEDVYEPFLIQRGFLERTPRGRKATALAYEHFNTTNEKRE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: FIS_ECOLC
Sequence: MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: MNL2_YEAST
Sequence: MSIARLVYSLFRRVRSVLLLFITISLLFYYTFQNEIDILNSYALNDSLPSINNYEHNTEGSSKLDPPDLSSTGSDRIATDKENGNVAVDLSDPATLREKNKYFPLLLKGSSHQIGSNLPISSLLTYKEKYPVLFEYSSPSLTSISQNDVHKIQPAMQLPPDVDMIKQIKDIFMKSWNQEQLLLKSNLRRESTWPIDLIDSLDTLYLCGETKLFQDSVNIIEDFDFRVPPLAMEVIDIPDITTRVLEGLLSAYELSMDKRLLNKAKHVADFILRSFDTPNRIPILKYFWKSDLRNRFPDRTVPSGQLTTMALAFIRLSQLTRLNKYFDAVERVFTTIRQSYNEFDMEFMLPDVVDASGCQLLTQEEIENGAHLKGSSIMKSINENFKFVHCQQLGKFLNPPIDDNSLQEQSQYQAYRINEKTVPILENLFKINDLFQSSYDILDGSSKNANAATMDPSIGSEVEAVDEIIEKRNFKDGTKKDSTKNTVGDKSLIDSQTFLTNSISNIFKFMTFRPMLPKQTENKKFNFLNSILTKSQFMPTTNELDVTIRKSYDVSLYSCRLGGILGLSSRVPHRGGVNTKYILPSSLLEMSEIITESCFMLMEEFDGLLPQKFELDPCTDETNGNCEFNGETKSRMIANGEYETFENDLDVGIKVSNYGKGGNDQKAKRNVLSKDGITETQNIKGDTVGSSKSIAEIDGDEVTQIRRVFTLGKDIKPHITTDDTMGSQWKNHPDWPFWVNKVESRRLLDSNIIESIFYMYRISGEQKWRSMGKQSFGILMQELMELNSGAKGLWQIKEFYENGEKVNNDLPSYWFSRTLKYYLLLFSDGDKVSLDKHILTQGGHIIKKK
What is the function of this protein?
Putative mannosidase involved in glycoprotein quality control since it is involved in the targeting of misfolded glycoproteins for ER-associated protein degradation (ERAD).
What are the official names of this protein?
Putative endoplasmic reticulum mannosidase MNL2, Mannosidase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 47 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: AGTR1_CHICK
Sequence: MVPNYSTEETVKRIHVDCPVSGRHSYIYIMVPTVYSIIFIIGIFGNSLVVIVIYCYMKLKTVASIFLLNLALADLCFLITLPLWAAYTAMEYQWPFGNCLCKLASAGISFNLYASVFLLTCLSIDRYLAIVHPVKSRIRRTMFVARVTCIVIWLLAGVASLPVIIHRNIFFAENLNMTVCGFRYDNNNTTLRVGLGLSKNLLGFLIPFLIILTSYTLIWKTLKKAYQIQRNKTRNDDIFKMIVAIVFFFFFSWIPHQVFTFLDVLIQLHVITDCKITDIVDTAMPFTICIAYFNNCLNPFFYVFFGKNFKKYFLQLIKYIPPNVSTHPSLTTKMSSLSYRPPENIRLPTKKTAGSFDAE
What is the function of this protein?
Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney.  The activated receptor in turn couples to G-alpha proteins G(q) (GNAQ, GNA11, GNA14 or GNA15) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.
What are the official names of this protein?
Type-1 angiotensin II receptor, Angiotensin II type-1 receptor, AT1 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CBIZ_METMA
Sequence: MQYHIKDQTLIIKGDFEAVSTGLNGGRARVEYIFNKQVPRTFNPPSPEEFIREEARKDGIETASLGLLTAVNMEYLQVIEDDYMTAFITAGVSNCSEFRAKAGTINIILVSKARLSETALFGAIITATEAKGLALLEKGYNFLGTNTDAVIVAYETCSDSGPKSKTNQEIPYAGSSTEFGKKITEAVIKGIKAGLELRGE
What is the function of this protein?
Converts adenosylcobinamide (AdoCbi) to adenosylcobyric acid (AdoCby), an intermediate of the de novo coenzyme B12 biosynthetic route.
What are the official names of this protein?
Adenosylcobinamide amidohydrolase, AdoCbi hydrolase.
What is the protein family that this protein belongs to?
Belongs to the CbiZ family.
Protein: CY550_TRIEI
Sequence: MKKFFISVVFIVLLTFTTFINSATAAKLDDNVRTLPLNEDKEVVLTIKEYTQGKREFTNVCSQCHVGGITKTNPDVSLDPETLALAYPARDNIEGLIDYMQNPTTYDGFIEISEFHPSIKSADIYPEMRNLTEDDLYAIAGYILVQPKVLGKQWGGGKIFR
What is the function of this protein?
Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II.
What are the official names of this protein?
Cytochrome c-550, Cytochrome c550, Low-potential cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PsbV subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with photosystem II at the lumenal side of the thylakoid membrane.
Protein: PDRP_LYSSC
Sequence: MKRLRVFVVSDSVGETGDQVAKAVISQFRPGLENTVIRRFPHIQSEELIRKIVFLAAQQQAFIVYTLVRQEMRKLLRDLCEQEKIHAVDIIGPALQSMATFMEENPLETPGIVHMLDDDYFKKIEAIEFAVKYDDGRDPRGLLQADIVLVGVSRTSKTPLSQYLAHKKYKVANVPLVPEVEPPEELLQLDPKKCFGLIISPEKLNSIRKERLMSLGLNDDAIYAQHNRILEEIQHFEKIVGKIGCRVIDVTNKAVEETANTIIEHILTCK
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: APO1_ORYSJ
Sequence: MMNPRRLPPLPSSTSSASAADDMDPRVWRRLPQPLVDRILACLPTPSFLRLRAACRRFYHLLFSSPFLHSHLLLSPHLPFFAFVVPAAGHLLLLDPTATASWSRLPLPLPPVAGGPAAFSPAAASAGLLAFLSDASGHKTLLLANPITRLLAALPISPTPRLSPTVGLAAGPTSIIAVVAGDDLVSPFAVKNISADTFVADAASVPPSGFWAPSSLLPRLSSLDPRAGMAFASGRFYCMSSSPFAVLVFDVAENVWSKVQPPMRRFLRSPALVELGGGREGAARVALVSAVEKSRLSVPRSVRLWTLRGGGGGGGGGAWTEVARMPPEVHAQFAAAEGGRGFECAAHGDYVVLAPRGPVAQAPTSALVFDSRRDEWRWAPPCPYVVVAHHGGAGAAGFRVFAYEPRLATPAIGLLDATAPVALHGMHDG
What is the function of this protein?
Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).  Together with FL/APO2, involved in the temporal regulation of meristem identity during both vegetative and reproductive developments in an APO2-dependent manner (PubMed:17666027, Ref. 5, Ref. 6, PubMed:15950602, PubMed:19386809, PubMed:21910771).  Promotes spikelet formation by suppressing the precocious conversion of inflorescence meristems to spikelet meristems, probably via a positive regulation of class-C floral homeotic genes, but not of class-B genes, and through the control of cell proliferation in meristems (PubMed:17666027, Ref. 6, PubMed:19386809, PubMed:21119645).  Mediates culm development and strength/diameter enhancement at internodes (PubMed:21119645, PubMed:25381289).  Required for the regulation of the plastochron, floral organ identity, and floral determinacy (PubMed:17666027, Ref. 6, PubMed:15950602, PubMed:19386809).  Controls the number of primary rachis branches (PRBs) (PubMed:20151298).  May trigger the formation of vascular bundle systems which, consequently, promote carbohydrate translocation to panicles (PubMed:20151298).  Involved in ozone-induced grain yield regulation (PubMed:25923431).
What are the official names of this protein?
Protein ABERRANT PANICLE ORGANIZATION 1, F-box protein 0393, Os_F0393, F-box protein 321, OsFbox321, Protein PRIMARY BRANCH NUMBER ON CHROMOSOME 6, Protein STRONG CULM 2.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS18_BORBZ
Sequence: MYKDRDTNQRDSRFENQQDGFKKNSNFRFFKRKSCKFCDSGKHPDYKDFDFLKKFITEQGKILPKRITGTSAKHQRRLALEIKRARYMALLPFVKK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.