PharMolix/UniProtQA huggingface dataset:
Protein: NU5M_PATPE
Sequence: MNINPSIIILTINISIIITLLSSVFFFQNETNPSNLNSSSYSLGIFHNTSFNYLFSNSLFFTSLLKTLAILSLFPLFIEIIFNIPDTTVSLFNWLPNNGFSLNVEFRFDLKFNTFLSVALIVSWSILEFSYYYMDNDPNPNNFFRLLIIFLLNMIILTSTNNIFLLFIGWEGVGFLSFLLISWWTSRANANNSAIQAVIYNRVGDIGILLFFSLSITLFNTWSLPEIFSISAPNTFNNLLLVGLLIAAAGKSAQFGLHPWLPAAMEGPTPVFSIRHSSTMVVAGIFLLIRLSPLYACSSNFNTWCLILGSITAIFAATTAISQHDIKKIVAYSTTSQLGLMMVAIGLNQPSIALFHICTHAFFKAMLFLSSGSIIHSLNDEQDIRKMGGLHFILPNTAACIILGSLALSGIPFLPGFYSKDLILEIGLTNFSNFMGIVLSLLATLLTSVYSFRIIFFCFIKNPSFSPLAPINEENNNLTNSLNRLALGTILSGWILTNLTVLVPIITISSVLKTAALLLTITGVLFSISILQELTLNISPPTAYNTNSFTTNQWFYENISHILFLFYSFTISLSLSTRNIDRGWSENIGAQGIAITSSNASQSYQLSQTGYIKQYLLFSFLTLLIIIALSLTTISQLSPSFDI
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL28_ACTPJ
Sequence: MSRVCQVTGKRPAVGNNRSHALNATRRRFLPNLHTHRFWVESENRFVTLRLTAKGMRIIDKKGIDAVLAEIRARGEKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RECX_ECO81
Sequence: MTESTSRRPAYARLLDRAVRILAVRDHSEQELRRKLAAPIMGKNGPEEIDATAEDYERVIAWCHEHGYLDDSRFVARFIASRSRKGYGPARIRQELNQKGISREATEKAMRECDIDWCALARDQATRKYGEPLPTVFSEKVKIQRFLLYRGYLMEDIQDIWRNFAD
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VNN3_MOUSE
Sequence: MASLHFPQWAVSFVFFAQAVGSMDTFIAAVYEHAVILPNKTESPVSTEEALLLINKNIDILESAIKLAARQGAHIIVTPEDGIYGWIFTRETIYPYLEDIPDPEVNWIPCRDPRRFGYTPVQERLSCLAKENSIYIMANIGDKKPCNATDPHCPPDGRYQYNTNVVFDSKGRLTARYHKYNLFEPEIQFDFPKDSELVTFDTPFGKFGIFTCFDIFSYDPAVVVVKDTQVDSVLLPTAWYNTLPLLSAVPFHSVWARAMGVNVLAANTHNTSMHMTGSGIYSPEAVRVYHYDMETESGQLLLSELRSRPRQHATPAEVNWSAYARTVKPFSSGQADFPGKIYFDEFSFTKLTGSAGNYTVCQKDLCCHLTYKMSESRMDEVYVLGAFDGLHTVEGQYYLQICTLLKCQTTNSRTCGEPVGSAFTKFEEFSLSGTFRTKYVFPQIVLSGSQLALERYYEVSRDGRLRSRGGAPLPILVMALYGRVFERDPPRLGQGPGKLQ
What are the official names of this protein?
Vascular non-inflammatory molecule 3, Vanin-3.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor. Note=According to PubMed:11491533, secreted.
Protein: RL28_PARPJ
Sequence: MARVCQVTGKAPMSGNNVSHANNKTKRRFLPNLQSRRIWVESENRFVRLRISNAGLRLIDKNGIDSVLADLRARGEA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: SCIN_STAAE
Sequence: MKIRKSILAGTLAIVLASPLVTNLDKNEAQASTSLPTSNEYQNEKLANELKSLLDELNVNELATGSLNTYYKRTIKISGQKAMYALKSKDFKKMSEAKYQLQKIYNEIDEALKSKY
What is the function of this protein?
Involved in countering the first line of host defense mechanisms.  Efficiently inhibits opsonization, phagocytosis and killing of S. aureus by human neutrophils.  Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inactivation.  The convertases are no longer able to cleave complement C3, therefore preventing further C3b deposition on the bacterial surface and phagocytosis of the bacterium.  Also prevents C5a-induced neutrophil responses (By similarity).
What are the official names of this protein?
Staphylococcal complement inhibitor, SCIN.
What is the protein family that this protein belongs to?
Belongs to the SCIN family.
What are the subcellular locations of this protein?
Secreted.
Protein: YKQA_CAEEL
Sequence: MVDQIRSPSWKSGFPSHQHQQGSYWTQGSTSSYLSTAKTAGVLGDVAEKANKIAPILTTAAVIYEMYQVGKEVKKDYHHGTTRNTIKTVATTATTYASASAAALAGSSIGSAIFPGIGTIFGGIIGGIAGGLFGGHVAETASEQILTHVKYDVTTLTCKECGKDYDWKKYEEAQGVCSCQLQIVLSNDAATKLCAILAEKIQSPSQTSNYAFNSYLCYYYLHIFACLNKILNHK
What are the official names of this protein?
Uncharacterized protein C06E1.11.
Protein: PKS2_METAF
Sequence: MQPHRVFIFGDQTGGFATGLQQLLLDKTNPSLVYFVDHANLALRQELSRLPSTDREALPLIGSVQDILTLHKKGERNVVIDSILSTVYHLACFIYKYGNAGCAYPNGQDIHVTGMCVGSLAAAAVSCSRSIGDVIVAGIVAIRAALRVGLRAHQAALLISNRAAPHTHWSYAVSTESLRLDLIKDALEEFAQDMDTSPLSHPYISAIGLDSVTVSGPPSQLQQFWRENTTFHKPIPIPIWAPYHGPHIFGDSDVETIIESLHPIPKLSQQAPIISSGSGVMASQTLADLIRAALRDILLHRLDLPALVGHIKDIVRSSPNQDFSMTPIATNAATGLVAATAKAAGNKGSVDNEIMDAAALAGSASRATSAKTHDSKIAIIGMSGRFPEAADLDSFWSLLEQGVDAYRPVPPDRFDAHAHHDETGRRKNTSKVLGGCWINQPGLFDPKFFSISPKEAEQSDPAQRLALQTAYEALEMAGVVPDRTQSTQRDRVGVFYGMVSDDWREINSGQNIDTYFIPGGIRAFTPGRINYHFKFSGPSITVDTACSSSLAAIHVACNSLWRGDCDTAVAGGVNVLTNPDIFAGLDRGHFLSTTGNCKTFDDDADGYCRADGVGTVILKRLEDAVMDKDPILAILNSAYTNHSAEAVSITRPHAGAQELIFSKLLRETGIHPHDVSYIEMHGTGTQAGDATEMSSVLRTFAPDTRRLSSQTLHLGSAKSNVGHGEAASGVTSLIKVLLMMKHNTIPPHCGIKGRINHRFPTDLRERNVFIASQPVAWNKPHTGSGKRRVFINNFSAAGGNSALLLEDAPAGENPETKDPRSTHVVAVSAKSSTSLANNLKRLRDFVQDNIHDLDSLSKLSYTTTARRIHYPFRTAVTASSRDQLLQGIESVLLRDEMPKPCKSQKNIGFVFSGQGAQYAGMGRHLFQNNHTFRTQILACNQICLSQGFPSILEIFKQDVDMNSLEPLLVQLATTCLQMSLVSFWKSLGVTPDFCIGHSLGEYAALQAAGVLSVSDTIYLTGIRARMLQEKCSAGSHAMLAVRAPLARVNALLDPAIHEVTCLNGPQDVVIGGRVADVEALEKELAKQDIKAVKVSVPFAFHSTQVEPILGEFCDAARGVPFQTQTIPVVSTLLGEVVQPEAAGVFGPGYLKRHCREPVNFAAAVQAARDANVIHAGTVFVEIGPHPVCLALLKSNMGPDAVTLASLHRKDDGWKVLADTLAALYQSGLKINWDEVHRDFASCQEVLPLPSYSWDNKNYWIQYVHNWTLTKGDEPAAMAETTALQAQDGLTSSVQRIIRQTDGPGSLVTIVVQSDFGSARLADVAQGHKVNGEMLCTSSLYAEIGMTLGRHLLEKYRPDLDGYSTEIKDMSVDKPLILKDENKQTLFRAEVVHDKTTHTATMSIYSVDSAGNKTVDHARCLLRFADPTSWLDEWERTYYLIDRSVRWLEERAEQGTDSLLSKGIVYKLFSSLVDYSPSFKGLQEVILNSGDREAAAKVRLQAEKGDFDCNPMWIDSFGQLTGFLMNGHDFTGKDEVFINHGWRSMRCAKPFRKDAVYRTYIRMQHVEKTKYRGDLYIIEDGVIVAVFGGMTFLGMSRSLLNKVLPPRRGAEAINTPHPVAAAQQGMAASAKDTERRPLDIPTRAQRQPSSPQTGTMGRILAILSKEVGLSMETLTDDLVFTDYGVDSLLSLTITGRIREELGLDMDSSIFTHYSTLGELKAFLGADQPDDAVACESSIGQHTPQTSDKGSGTLASQKTDGDTGPDTTLNRVCAIIAEEVGISVQELSSSQDFQELGIDSLSSLTILSRVREELQLDLESDFFDTHPSFYALQKALCGSEASNGAPEANETTPSSDRLESDLRSITWQSGQNIVASPPHATSILVSGSPSTARMILVLFPDGSGSAASYGALAPKIRRDIAVYALNCPWRTNGEEILRLGVTLDQMVAKHLVEVGRILDSHQRGRPGSSNASVGLALGGWSAGGILALEAVRQLREAGVAVQKMVLLDAPNPIGLQNPPPRMFHFLDELGILGAGKGKAPAWVLRHFDAMVTLLKSYRPRRLGAEDAPKCLIVYAKDGICKDPNGPRMDTKPDDAREMLWLLYNRVDFSAEGWKTLVGPQNLAVGVVEDVNHFSMMNPGPKMVEMGNLIGDFLLGPS
What is the function of this protein?
Polyketide synthase; part of the Pks2 gene cluster that mediates the formation of infectious structures (appressoria), enabling these fungi to kill insects faster (Probable).  The product of the Pks2 gene cluster is different from the one of Pks1 and has still not been identified (Probable).
What are the official names of this protein?
Polyketide synthase 2.
Protein: SYI_DESDA
Sequence: MSDYKKTLNLPQTAFPMKANLAQREPEAIKKWEAANACAAMVEASGSEGTYILHDGPPYANGHLHMGHALNKILKDIIVKSRNMAGYASWYVPGWDCHGLPIEHKVEQDLKEKKKSLPAHVVRKLCREYANKWLDVQRKEFKRLGVLGDWDHPYISMDPAYEAVTAGELAKFVAAGGVARAKKPIYWCCSCHTALAEAEVEYNDHTSPSVYVRFALPDEGLKKVFAAADPARAHVVIWTTTPWTLPDNMAVCLHPEFTYALVEAEGSQYILAEELVASCAETFGWSEYTILDRATGERLEGLKARHPFYDRQSSLVLGLHVTLDAGTGCVHTAPGHGREDYDVALKYGLEIYSPMDDAGRFLPAVEFFAGLNVFEANPKVVEKLEEVGALLQKGKIRHSYPHCWRCKEPVIFRATTQWFISMEKNDLRTRALKAIDEEVRWIPAWGRERIHNMVEFRPDWCISRQRQWGVPILALLCEDCGEAWNDPAWMQEIAARFAKHPTGCDYWYEAELKDVVPEGLACPHCGGNHWKRETDILDVWFDSGTSFAAVLEKRPELGFPADLYLEGSDQHRGWFHSSLLVSEGTRGCAPYRAVLTHGYVVDGDGRKMSKSVGNVIAPQELIEKFGAEIVRLWVSSVEYREDIRLSDEILGRLVDAYRRIRNTCRFIMGNLSDITAHDLLSLDRLQPLDRFALDVAGRVHERVQQAYMDFDFHKVYHTLHNYCVTDLSSVYLDILKDRLYASAPHSDERRSAQTALWHILCLLLRDMAPVLSFTAEEIFSHLPESLRGPETTVFALPPLAAAPYLLDEGTRDDWNVLLAVRGAVTKAIEPMRREGIIGHSLDTRITLFVADELRQRLEGLHTDLRAVCIVSQLHLEALDRAPQAAYRDEEVAGLAIGVEKARGEKCERCWIYSTELGSDASHPALCPRCTAVIKGMES
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTCB_MYCTU
Sequence: MQVVNVATLPGIVRASYAMPDVHWGYGFPIGGVAATDVDNDGVVSPGGVGFDISCGVRLLVGEGLDREELQPRLPAVMDRLDRAIPRGVGTAGVWRLPDRNTLQEVLTGGARFAVEQGHGVALDLERCEDGGVMTGADAAKISDRALQRGLGQIGSLGSGNHFLEVQAVDRVYDPVAAAPMGLAEGTVCVMIHTGSRGLGHQICTDHVRQMEQAMGRYGIAVPDRQLACVPVHSPDGQAYLAAMAAAANYGRANRQLLTEATRRVFADATGTPLDLLYDVSHNLAKIETHPIDGQLRSVCVHRKGATRSLPPHHHELPAELAAVGQPVLIPGTMGTASYVLAGVTGNPAFFSTAHGAGRVLSRHQAARHTSGEAIRASLAKRGIIVRGTSRRGIAEEKPEAYKDVDEVIEASHQSGLARKVARLVPLGCVKG
What is the function of this protein?
GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair.  Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends.
What are the official names of this protein?
RNA-splicing ligase RtcB, 3'-phosphate/5'-hydroxy nucleic acid ligase.
What is the protein family that this protein belongs to?
Belongs to the RtcB family.
Protein: ISPG_KORVE
Sequence: MPTIYRRKTPVVRIGDVWVGSDAPVVVQSMTNTDTADVDSTIKQCIALARAGSELIRVTVNNDDAAKGVPHLVDGLAKIGIHTPIIGDFHYNGHILLKKYPDCAKALAKYRINPGNVSIGRKDDDNFKAMVDVAVENQKPVRIGVNWGSLDQQLLAKMMDQNAKLAEPKEARDVMMEAMIVSALNSAAIAERYGLRKDQIILSAKVSGVQDLIDVYRDLAKRCDYVLHLGLTEAGMGAKGVVASTAGLSVLLLEGIGDTIRVSLTPKPNGDRTEEVLVAQQILQSMAIRSFTPQVTACPGCGRTTSTFFQELAERIQNYIREQMPQWKTRYTGVEEMKVAVMGCVVNGPGESKHANIGISLPGTFEEPKAPVYVDGRLMTTLKGDKIVEEFTTILNEYVDNRYAKKAEEAVGV
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: CYB_CRYPR
Sequence: MTNIRKTHPLMKIINSSFIDLPTPSNISSWWNFGSLLGICLIIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMFMETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGSDLVQWIWGGFSVDKATLTRFFAFHFILPFVIAALAGVHLLFLHETGSNNPSGLPSDADKIPFHPYYTIKDILGILLLILVLTCLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAFIPLLHTSKQRSMMFRPLSQCLFWILVADLLTLTWIGGQPVEHPFIIIGQLASILYFMLLLVIMPITSLLENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ECM14_ARTBC
Sequence: MHFSVRLSLFLTLASSLPLVSAVPQHEDQAYTFSSSGRSAATDTDPALEVRQETQRTPSAWTRLRDSLVESVWGLPQRSEGCESRPRNRAKTVSRAPATLQARYGEDVVLRFTIKNQEEVKALVEASNILFLDVWGSHDDWVDIRLSRDVIPSLLGLLPPSLQTSHVPLIRDLAQTIYESYPKAGSASPSQQGPTTRRFSPSASTSKSKPHETKNIFFQDYQPLSVLLPWMRLLVSMFSSHTTLISVGTTAEGRDIPALRVGVHPTNNAQQAPRRRTIVISGGTHAREWISVSTVSYIAYSFITGYGKSKSITKLLEQFDYVFIPTVNPDGYAYTFSTDRLWRKNRQQTSLSFCPGIDLDHSWGYEWDGNATRSNPCSESYAGDQPFEAVEAREIASWARNEVTVNNVHFVAFVDLHSYSQQILYPYGHSCAHLPANLENLEELGAGLAKAIRKSSRENYDVKAACRGIVASCTGDKDADEPATSSALESTAGSALDWFFHDLDVRFSYQIKLRDRGSYGFLLPREHIVPTGKEIYRAMVAMGKFLVSPHVLEEDIDGLRASEEPQDYDNDLEDGEDDKDEQGSTVFRAQADDLQS
What is the function of this protein?
Inactive carboxypeptidase that may play a role in cell wall organization and biogenesis.
What are the official names of this protein?
Inactive metallocarboxypeptidase ECM14.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Vacuole. Secreted.
Protein: TATA_FLAJ1
Sequence: MGRLGLTEILVIVGIVILLFGGKKIPELMKGLGSGIKEFKNAAKDDQPAPAKKQEEEQK
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: IMM1_PSEAI
Sequence: MKSKISEYTEKEFLEFVEDIYTNNKKKFPTEESHIQAVLEFKKLTEHPSGSDLLYYPNENREDSPAGVVKEVKEWRASKGLPGFKAG
What are the official names of this protein?
Pyocin-S1 immunity protein.
What is the protein family that this protein belongs to?
Belongs to the colicins ColE2/ColE8/ColE9 and pyocins S1/S2 family.
Protein: RS15_RHOP5
Sequence: MSIAAERKAEVIKTNARKDGDTGSPEVQVAILSERIANLTAHFKTHVKDNHSRRGLLKLVSTRRSLLDYVKKRDEARYKALLEKHNIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: DEH1_MORSB
Sequence: MDFPGFKNSTVTVDGVDIAYTVSGEGPPVLMLHGFPQNRAMWARVAPQLAEHHTVVCADLRGYGDSDKPKCLPDRSNYSFRTFAHDQLCVMRHLGFERFHLVGHDRGGRTGHRMALDHPEAVLSLTVMDIVPTYAMFMNTNRLVAASYWHWYFLQQPEPFPEHMIGQDPDFFYETCLFGWGATKVSDFDQQMLNAYRESWRNPAMIHGSCSDYRAAATIDLEHDSADIQRKVECPTLVFYGSKGQMGQLFDIPAEWAKRCNNTTNASLPGGHFFVDQFPAETSEILLKFLARNG
What are the official names of this protein?
Haloacetate dehalogenase H-1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.
Protein: VL2_COPV6
Sequence: MALIRKRRAAPQDIYPACKVSNTCPADILNKMEQNTLADKILKYGSAGVFLGGLGISTGKGVGGRTGYIPLGGTESGVGVGTRVTTIRPTVPISSVGSPDFIPVDAVDPLGPAVIPPERFPIAVEDPFTLPPPRFPTAVEEDVIELQPIPGPSSEIPLAGPKITTDAQPAILEVIPETRPPKVITRHQYSNPAFEVSITSNSGAGESSASDHVLVEGFSGGHSIGEHIPLQDLAPSRPSFSETIEDETAFSSSTPKQGSRSERPKSYYNRRRYQQVQVTDPVFISRPRSLVTFDNPAFDESVDLIFERDVAEITAAPHADFTDITKLTKPAYHRGPSGHVRVSRLGHRANIKTRSGLTIGPQSHFYYDVSSIDPAESFELQALGNVSSAEQTGEAVISSGTGDFEIISLEDSILESYNDEDLIDVFEDVARDLHLLVGERRQQPIQVQRYIKPFSFVNEGVHIIHPGSESDFWLPPVTPDSTPAIVIDILDSSADYYLHPSLIKKRKRKHFFF
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: YOEI_ECOLI
Sequence: MGQFFAYATVITVKENDHVA
What are the official names of this protein?
Uncharacterized protein YoeI.
Protein: GRPE_SHESM
Sequence: MSNESIKAEQDLIQEGVESEVSTEEASLIDELTQANFRIEELEQLLADALAKVEEQKDSVIRAAAEVDNIRRRAAMDVEKANKFALEKFANELLPVLDNMERALQGTNPQDETTKAIYEGVELTQKSLLTAVAKFGVKPIDPQGQAFNPDQHQAIGMQPSAEFPANTVMLVMQKGYELNSRLLRPAMVMVSQGGPSQEINIEA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR18_PHATC
Sequence: MVSKKQKLSPISLNQNIDYKDIDLLTLFVTEQGKILPRRATGVTVQQQRRLAKAIKRARVLSLFPFVASNSI
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YEAH_SALDC
Sequence: MTWFIDRRLNGKNKSTVNRQRFLRRYKAQIKQSISEAINKRSVTDVDSGESVSIPTDDISEPMFHQGRGGLRHRVHPGNDHFIQNDRIERPQGGGGGGSGSGQGQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKKNQHRQLNEYKTHRAGFTSNGVPANISVVRSLQNSLARRTAMTAGKRRELHALETELETISHSEPAQLLEEERLRREIAELRAKIERVPFIDTFDLRYKNYEKRPEPSSQAVMFCLMDVSGSMDQATKDMAKRFYILLYLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVKERYDPGQWNIYAAQASDGDNWADDSPLCHEILAKKLLPVVRYYSYIEITRRAHQTLWREYEHLQATFDNFAMQHIRDQEDIYPVFRELFQKQSANQSV
What are the official names of this protein?
UPF0229 protein YeaH.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: RPOZ_ECOLU
Sequence: MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RL16_PSEA8
Sequence: MLQPKRTKFRKQMTGHNRGLAHRGSKVSFGEYALKATSRGRLTARQIESARRALTRHVKRGGKIWIRVFPDKPVTKKPLEVRMGKGKGGVEYWVAQIQPGKVLYEIEGVSEELAREAFALAAAKLPLATSFVKRTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: COX3_RICCN
Sequence: MSQKIILNNSYSITKSHLFHIVDPSPWPVLTSFALLLLVIGGVSFMHGYKFNIYILSAGIISVGYCLYSWWRDIVKEGIVEHQHTSPVRKGLQIGMALFILTEIVFFGVFFASFFKSSLSPVGLLDGVWVVKQGIWPPPTIKTFEPFDIPFINTLILLLSGTTVTWAHYALEEKNQKDCVTALALTILLGIFFTTMQAYEYYHAAFKFTDGIYASNFYLATGFHGAHVIIGTIFLIICYFRAKRGDFTTEGNGHLGFECAAWYWHFVDVVWLFLFTFVYIFGS
What are the official names of this protein?
Probable cytochrome c oxidase subunit 3, Cytochrome aa3 subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ZB183_XENLA
Sequence: MEFPEHSRHLLQCLSEQRHQGFLCDCTVLVGDAHFRAHRAVLASCSMYFHLFYKDQLDKKNIVYLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEKATTEADSTKKEEDTLSCSDKIECLSDGSSHMAGDLPSDEDDVEEEKINSKTDLATESGNMWIRLSSDSASIPQTGGEVDTHTTAAGKTADSPCSSTGSLSHRSATSMGDSTDVDCVLDLSVKSSLSGTETLNNSYLSSQEILRNSLVQVKIEREASCEDNDIHTSEYDIERNTVKENVSSNIRAPYEPVHLAPIREDSVLRELDHDDKAINDDMITPENERVQMEANIDNSLLPYVQNILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQEGIRSKPTNDVHVPTCSLCGKTFSCMYTLKRHERTHSGEKPFTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIRKFHCELVNSLSVKSETLGLPAVRDWTLEDSSQELWK
What is the function of this protein?
Transcriptional repressor that plays a role in various developmental processes.  Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes (By similarity).
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 18.3, Zinc finger protein 238.3.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family. ZBTB18 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CRL_VIBPA
Sequence: MSETTQGPTHFRLMSKLKAIGPYLREPQSQEGRYYFDCLSVCVDDKKSPEKREFWGWWMDLESIEGGFTAKYHIGKYNKEGKWVSEALPQKVVEEVYFTQSTFHQKLIDTLAEHFKLEVEYHTESFDFA
What is the function of this protein?
Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes.  Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
What are the official names of this protein?
Sigma factor-binding protein Crl.
What is the protein family that this protein belongs to?
Belongs to the Crl family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_IDILO
Sequence: MANYSTSEFKGGLKIMQDGEPCSIVENEMVKPGKGQAFNRVKIRKLISGKVVEKTFKSGESVEGADVIELELSYLYNDGEFWHFMNNETFEQVPADEKAVGEAEKWLVEQDVCTLTLWEGKPINVQPPNFVELEITETDPGLKGDTAGTGGKPATLSTGAVVRVPLFVQIGEVIKVDTRSGEYVSRVQK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PBP7_HAEIN
Sequence: MFKKALFILSLCPSFALAQSYVVYDFTHNRVLESHASDSIQPIASVTKLMTANVFLENNKNPNCRIAITKEDTDRIKGTGTKLPKNIPISCNELLKAMLVHSDNYAAHALSRAAGISRRQFIKKMNEKAHQLGMYSTRFHDSSGLSSYNISSPMDLVKLAKYSLNKSDIKRLSNLSATYIQAGKQKLYIKNTNKLVRDEIFDAAVNKTGYIQESGYNLVFINKHRCKNATIGVISLNNTSSAYRSSFTKSKLEKFGCTALNGRTIRDVAGEAQYEDGYDEVGFNTLIQKLSK
What is the function of this protein?
Cell wall formation.  May play a specialized role in remodeling the cell wall.  Specifically hydrolyzes the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi (By similarity).
What are the official names of this protein?
D-alanyl-D-alanine endopeptidase, DD-endopeptidase, Penicillin-binding protein 7 homolog, PBP-7.
What is the protein family that this protein belongs to?
Belongs to the peptidase S11 family.
What are the subcellular locations of this protein?
Periplasm.