PharMolix/UniProtQA huggingface dataset:
Protein: Y1612_MARN8
Sequence: MMNNMGDLMKKAQQMQEQMQKAQEEIAKAEVTGESGAGLVKVTMNGRHDVRKVDIDPSLLSEDKEILEDLLAAAVNDAVRRVEANQKDKMSGMMSGMGMPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Maqu_1612.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: LEU3_ECOL6
Sequence: MSKNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPATVEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEKAFDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPDVELTHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYSLDADDAASAIERAINRALEEGIRTGDLARGAAAVSTDEMGDIIARYVAEGV
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBS_METAR
Sequence: MAGNLLNGLRAAIAFLTTLPVRIVDGDYDAFADRQYLFIPVAIVTGLLLGVAGTLFQCILPAPFAAVLTVACIFLLTGINHLDGLSDFGDGLIASGPREKKVRAMKDVHAGAGGLLFMAMDLLFLFALAMTFAGSPTWLFVPLLVAEGCAKVAQITIIAFGKSAHEGMGSYMIARMKKEHYLAAVIGAWIAIGIAIIGAAIIPGGGNPLRVIMAGGLAMLSPLAVALIILIISDRNFGGVNGDVIGAANEIARIAALGVMGAVLWMRF
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SCNND_PANTR
Sequence: MAEHRSMDGRMEAATRGGSHLQAAAQTPPRPGPPSAPPPPPKEGHQEGLVELPASFRELLTFFCTNATIHGAIRLVCSRGNRLKTTSWGLLSLGALVALCWQLGLLFERHWHRPVLMAVSVHSERKLLPLVTLCDGNPRRPSPVLRHLELLDEFARENIDSLYNVNLSQGRAALSAPVPRHEPPFHLDREIRLQRLSHSGSRVRVGFRLCNSTGGDCFYRGYTSGVAAVQDWCHFHYVDILALLPAAWEDSHGSQDGHFVLSCSYDGLDCQARQFRTFHHPTYGSCYTVDGVWTAQRPGITHGVGLVLRVEQQPHLPLLSTLAGIRVMVHGRNHTPFLGHHSFSVRPGTEATISIREDEVHRLGSPYGHCTAGAEGVEVELLHNTSYTRQACLVSCFQQLMVETCSCGYYLHPLPAGAEYCSSARHPAWGHCFYRLYQDLETHRLPCTSRCPRPCRESAFKLSTGTSRWPSAKSAGWTLATLGEQGLPRQSHRQRSSLAKINIVYQELNYRSVEEAPVYSVPQLLSAMGSLCSLWFGASVLSLLELLELLLDASALTLVLGGRRLRRAWFSWPRASPASGASSIKPEASQMPTPAGGTSDDPEPSGPHLPRVMLPGVLAGVSAEESWAGPQPLETLDT
What is the function of this protein?
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride.  Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells.  Controls the reabsorption of sodium in kidney, colon, lung and sweat glands.  Also plays a role in taste perception.
What are the official names of this protein?
Amiloride-sensitive sodium channel subunit delta, Delta-NaCH, Epithelial Na(+) channel subunit delta, Delta-ENaC, Nonvoltage-gated sodium channel 1 subunit delta, SCNED.
What is the protein family that this protein belongs to?
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1D subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PPR67_ARATH
Sequence: MLLFSSSSLQLREIFFPRIFSVFVKLNFLNSRGFSSDSAKALAAGISKAIKEGNFNLLDSSVYGSNLQRNETNLVLLSLESEPNSALKYFRWAEISGKDPSFYTIAHVLIRNGMFDVADKVFDEMITNRGKDFNVLGSIRDRSLDADVCKFLMECCCRYGMVDKALEIFVYSTQLGVVIPQDSVYRMLNSLIGSDRVDLIADHFDKLCRGGIEPSGVSAHGFVLDALFCKGEVTKALDFHRLVMERGFRVGIVSCNKVLKGLSVDQIEVASRLLSLVLDCGPAPNVVTFCTLINGFCKRGEMDRAFDLFKVMEQRGIEPDLIAYSTLIDGYFKAGMLGMGHKLFSQALHKGVKLDVVVFSSTIDVYVKSGDLATASVVYKRMLCQGISPNVVTYTILIKGLCQDGRIYEAFGMYGQILKRGMEPSIVTYSSLIDGFCKCGNLRSGFALYEDMIKMGYPPDVVIYGVLVDGLSKQGLMLHAMRFSVKMLGQSIRLNVVVFNSLIDGWCRLNRFDEALKVFRLMGIYGIKPDVATFTTVMRVSIMEGRLEEALFLFFRMFKMGLEPDALAYCTLIDAFCKHMKPTIGLQLFDLMQRNKISADIAVCNVVIHLLFKCHRIEDASKFFNNLIEGKMEPDIVTYNTMICGYCSLRRLDEAERIFELLKVTPFGPNTVTLTILIHVLCKNNDMDGAIRMFSIMAEKGSKPNAVTYGCLMDWFSKSVDIEGSFKLFEEMQEKGISPSIVSYSIIIDGLCKRGRVDEATNIFHQAIDAKLLPDVVAYAILIRGYCKVGRLVEAALLYEHMLRNGVKPDDLLQRALSEYNPPKWLMSKGVWVHDKPMPD
What are the official names of this protein?
Putative pentatricopeptide repeat-containing protein At1g31840.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
Protein: RL34_GLAP5
Sequence: MKRTFQPSVLKRARTHGFRARMATKNGRQVLARRRAKGRKSLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: ISPF_FRATN
Sequence: MSFRIGHGYDVHKFTSAKQNIIIGGVEIAYHLGLEAHSDGDVLIHALCDAILGALGLGDIGKHFPDTDNQFKNIDSKFFLAEIKKMLDEKQYSINNIDCTIIAQAPKMLPHIEKMRACLANILEIQISQINIKATTTERLGFIGREEGIATHVVCLLYR
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: ARFA_MYCBP
Sequence: MASKAGLGQTPATTDARRTQKFYRGSPGRPWLIGAVVIPLLIAAIGYGAFERPQSVTGPTGVLPTLTPTSTRGASALSLSLLSISRSGNTVTLIGDFPDEAAKAALMTALNGLLAPGVNVIDQIHVDPVVRSLDFSSAEPVFTASVPIPDFGLKVERDTVTLTGTAPSSEHKDAVKRAATSTWPDMKIVNNIEVTGQAPPGPPASGPCADLQSAINAVTGGPIAFGNDGASLIPADYEILNRVADKLKACPDARVTINGYTDNTGSEGINIPLSAQRAKIVADYLVARGVAGDHIATVGLGSVNPIASNATPEGRAKNRRVEIVVN
What is the function of this protein?
May play a role in ammonia secretion that neutralizes the medium at pH 5. 5, although it does not play a direct role in ammonia transport.  Binds peptidoglycan (By similarity).  Expression depends on arfB and arfC.
What are the official names of this protein?
Peptidoglycan-binding protein ArfA, Outer membrane protein A, OmpATb, Outer membrane protein ArfA.
What is the protein family that this protein belongs to?
Belongs to the outer membrane OOP (TC 1.B.6) superfamily. ArfA family.
What are the subcellular locations of this protein?
Cell outer membrane. Note=Does not have a cleavable signal sequence.
Protein: CYSH_SALTY
Sequence: MSQLDLNALNELPKVDRVMALAETNAQLEKLSAEERVAWALENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQEARYGKLWEQGVEGIEKYNEINKVEPMNRALKELKAQTWFAGLRREQSGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTCA_ECO8A
Sequence: MKRMIALDGAQGEGGGQILRSALSLSMITGQPFTITSIRAGRAKPGLLRQHLTAVKAAAEICRATVEGAELGSQRLVFRPGTVRGGEYRFAIGSAGSCTLVLQTVLPALWFADGPSRVEVSGGTDNPSAPPADFIRRVLEPLLAKIGIHQQTTLLRHGFYPAGGGVVATEVSPVASFNTLQLGERGNIVQMRGEVLLAGVSRHVAEREIATLAGSFSLHEQNIHNLPRDQGPGNTVSLEVESENITERFFVVGEKRVSAEVVAAQLVKEVKRYLASPAAVGEYLADQLVLPMALAGAGEFKVAHPSCHLLTNIAVVERFLPVRFGLIETDGVTRVSIE
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOK_NITEC
Sequence: MVSLSHYLVLGAVLFAIGVVGIFLNRKNVIILLMSIELMLLAVNINFVAFSYYLQDIAGQIFVFFILTVAAAEAAIGLAILVALFRNIRTINVDDLDRLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YACG_RHOBA
Sequence: MEPPVKINCPTCGRRFLSDETPAMPFCSKRCQLIDLGRWMNEEIGLPHEGDPGDAPVEYLDDRDLTQPSPERQNESFHRYSE
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: YBEY_COXB2
Sequence: MISIDVQHATQFEDLPSLSNIEQWVETALQFIVTDKNKSALTIRFIDKEESTELNEHYRHKKGPTNVLSFPDEPIPGFPSESFGDLAICAPLVAEEAHAQHKTTEAHFAHLITHGFLHLLGYDHVENEDAEEMENLEIKILSQLGFENPYEE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF11_BURP0
Sequence: MAKEELIELDGIVDEVLPDSRYRVTLDNGVVVGAYASGQMRRHRIRILAGDRVTLELSVYDLTKGRINFRHKDERRSDAAPRASARRR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1 1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_MOOTA
Sequence: MAKEITVLGSTGSIGRQTLEVVAAHPGRFRVAALVAARNDELLAAQVRRFRPRLAVLLDEERARVLAEMVSDPGIRILAGEEGLMAAACLEGVELVVAAMVGIRSLKAILAALEAGKDIALANKEVLVAAGQLVMDRARRLSRQIIPVDSEHSAIFQCLRQGGRVAEVIITASGGPLRQMPRAEMANVTPEQALNHPTWVMGPKITIDSATLMNKGLEVIEAKHLFNLDFDQIKVLIHPQSVVHALVRYSDGALFAQLGPADMRLPIQYALTWPERWDLDVQPLDLAALGHLEFALPDLERFPCLELALQAGRAGGTYPAVLSAADEVAVEYFLAGKITLTAISQVVGRVLDEHQPEPVPDLEGILAADAWARRRAGAVAEGLSF
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: M940_ARATH
Sequence: MRKSADEMFIGVRRAPISSNVGGTSFYGGDEYCSYYQSNGGVAKEDDGSAKKGFRRTGKGKLTAEAVSEAINRAAQGLPFEVVYYPTAGWSDFVVKAEDVEASMAIFWTPGTRVKMAMETEDSSRITWFQGIVFYTYQETGPWRGSPWNSFRYKIPFTIPLIFL
What are the official names of this protein?
Uncharacterized mitochondrial protein AtMg00940, ORF164.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: UDG_ECOL6
Sequence: MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISPIVDKEIQQFLQSDKIHFNATLDKNEAYRDADYVIIATPTDYDPKTNYFNTSSVESVIKDVVEINPYAVMVIKSTVPVGFTAAMHKKYRTENIIFSPEFLREGKALYDNLHPSRIVIGERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAIVDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYEPVMKEDSFFNSRLERDLATFKQQADIIISNRMAEELKDVADKVYTRDLFGSD
What are the official names of this protein?
UDP-glucose 6-dehydrogenase, UDP-Glc dehydrogenase, UDP-GlcDH, UDPGDH.
What is the protein family that this protein belongs to?
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
Protein: GRPE_BACTN
Sequence: MDPKEKEKMAEELNVEETKDTAEEQPQDDQAEEAAPLTHEEQLEKELEDAQAVIEEQKDKYLRLSAEFDNYRKRTMKEKAELILNGGEKSISSILPVIDDFERAIKTMETAKDVKAVKEGVELIYNKFMAVMAQNGVKVIETKDQPLDTDYHEAIAVIPAPSEEQKGKILDCVQTGYTLNDKVIRHAKVVVGE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTP3_SAPPC
Sequence: MLEVPVWIPILAFAVGLGLGLLIPHLQKPFQRFSTVNDIPKEFFEHERTLRGKVVSVTDGDTIRVRHVPWLANGDGDFKGKLTETTLQLRVAGVDCPETAKFGRTGQPFGEEAKAWLKGELQDQVVSFKLLMKDQYSRAVCLVYYGSWAAPMNVSEELLRHGYANIYRQSGAVYGGLLETFEALEAEAREKRVNIWSLDKRETPAQYKARK
What is the function of this protein?
Effector involved in the disease saprolegniosis in salmonids and other freshwater fish, resulting in considerable economic losses in aquaculture (PubMed:29904064).  Within the host fish cells, Htp3 is released from vesicles into host cytosol where it degrades nucleic acids (PubMed:29904064).
What are the official names of this protein?
Endonuclease Htp3, Host targeting protein 3, RxLR effector protein Htp3.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the LCL3 family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm, host cytosol. Note=Uptake into host cells is more efficient at a lower pH of 5.5. S.parasitica acidifies the pH of its environment, which likely leads to the exposure of a gp96 protein to the host cell surface. The gp96 protein is working as a receptor and mediates the translocation of Htp3 via lipid rafts into the cell. Finally, Htp3 is released from vesicles with the help of other effector proteins, such as Htp1, into the cytosol where it is functionally active as a nuclease.
Protein: GATC_PROMA
Sequence: MTRISSDDVRKVSKLARLEISEEHVETYANQLEEILEYIAQLEKIDTKNIPPTTRAVEVVNVLREDIVDKSNVRDKILDLAPNREGQFYRVPKILAE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: RL25_ECO27
Sequence: MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGKEAPLAVELDHDKVMNMQVKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLLHIDFVRA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: GSA_PSEA7
Sequence: MSRSETLFSNAQKHIPGGVNSPVRAFKSVGGTPLFFKHAEGAYVLDEDDKRYVDYVGSWGPMILGHSHPDVLDAVRRQLDHGLSYGAPTALEVEMADLVCAMVPSMEMVRMVSSGTEATMSAIRLARGYTGRDSIIKFEGCYHGHSDSLLVKAGSGALTFGVPNSPGVPAAFAKHTLTLPFNDIEAVRETLAEVGTDVACIIVEPVAGNMNCVPPAPGFLEGLREACDEHGVVLIFDEVMTGFRVALGGAQAYYGVTPDLSTFGKIIGGGMPVGAFGGKREIMQQISPLGPVYQAGTLSGNPLAMAAGLTTLRLISRPGFHDELGAYTTRMLEGLQQRADAAGIPFVTTQAGGMFGLYFTDAEAIVTFEDVMTSDVERFKRFFHLMLDGGVYLAPSAFEAGFTSIAHGDRELEITLNAAEKAFAALK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAC_SULTO
Sequence: MKPKPSQFKNLERMLGLKTEQLDAVKVTIELKDKILIIENPTVIKMIAQGQEIYSVIGEAKEAQKEEPKVEIKDEDVKFVMEQTGKGEQEVKEALQKANGDIAKAILLLTGQET
What is the function of this protein?
Contacts the emerging nascent chain on the ribosome.
What are the official names of this protein?
Nascent polypeptide-associated complex protein.
What is the protein family that this protein belongs to?
Belongs to the NAC-alpha family.
Protein: YJJB_ECOL5
Sequence: MGVIEFLLALAQDMILAAIPAVGFAMVFNVPVRALRWCALLGAIGHGSRMILMTSGLNIEWSTFMASMLVGTIGIQWSRWYLAHPKVFTVAAVIPMFPGISAYTAMISAVKISQLGYSEPLMITLLTNFLTASSIVGALSIGLSIPGLWLYRKRPRV
What is the function of this protein?
Involved in succinate export with YjjP.  Both proteins are required for export.
What are the official names of this protein?
Probable succinate transporter subunit YjjB.
What is the protein family that this protein belongs to?
Belongs to the ThrE exporter (TC 2.A.79) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SEPF_CALS4
Sequence: MSSKVIDKIMSFLGIEEEEEEIQTPQPVVSYDRRPKVVNIHTNPQIKVLISKPEKFEQVLSICNELKSKKPVIVDLQKMDKSEAQRVVDFLSGAVYALNGEITKISGYIFLVAPENFDVTGDIKEEVNALYNLN
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: HYPA_CHLAA
Sequence: MHELSIAHNIVTIASDAAAEAGVDRISAVHLRIGALAGVVADALRFSFAIAAEGTPLAGAELIIEEVPVVVFCPDCNAEVTLTNPRLFRCPRCDRPCGQIVHGRELELVALETP
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: PANB_ECOL5
Sequence: MKPTTIASLQKCKQDKKRFATITAYDYSFAKLFADEGINVMLVGDSLGMTVQGHDSTLPVTVADIAYHTAAVRRGAPNCLLLADLPFMAYATPEQAFENAATVMRAGANMVKIEGGEWLVETVQMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAGDRLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIGAGNVTDGQILVMHDAFGITGGHIPKFAKNFLAETGDIRAAVRQYMAEVESGVYPGEEHSFH
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK36_DIOEL
Sequence: MKIRASVRKICEKCRLIRRRGRIMVICSNPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IFNG_SHEEP
Sequence: MKYTSSFLALLLCVLLGFSGSYGQGPFFKEIENLKEYFNASNPDVAKGGPLFSEILKNWKEESDKKIIQSQIVSFYFKLFENLKDNQVIQRSMDIIKQDMFQKFLNGSSEKLEDFKRLIQIPVDDLQIQRKAINELIKVMNDLSPKSNLRKRKRSQNLFRGRRASM
What is the function of this protein?
Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation.  Primarily signals through the JAK-STAT pathway after interaction with its receptor IFNGR1 to affect gene regulation.  Upon IFNG binding, IFNGR1 intracellular domain opens out to allow association of downstream signaling components JAK2, JAK1 and STAT1, leading to STAT1 activation, nuclear translocation and transcription of IFNG-regulated genes.  Many of the induced genes are transcription factors such as IRF1 that are able to further drive regulation of a next wave of transcription.  Plays a role in class I antigen presentation pathway by inducing a replacement of catalytic proteasome subunits with immunoproteasome subunits.  In turn, increases the quantity, quality, and repertoire of peptides for class I MHC loading.  Increases the efficiency of peptide generation also by inducing the expression of activator PA28 that associates with the proteasome and alters its proteolytic cleavage preference.  Up-regulates as well MHC II complexes on the cell surface by promoting expression of several key molecules such as cathepsins B/CTSB, H/CTSH, and L/CTSL (By similarity).  Participates in the regulation of hematopoietic stem cells during development and under homeostatic conditions by affecting their development, quiescence, and differentiation (By similarity).
What are the official names of this protein?
Interferon gamma, IFN-gamma.
What is the protein family that this protein belongs to?
Belongs to the type II (or gamma) interferon family.
What are the subcellular locations of this protein?
Secreted.