PharMolix/UniProtQA huggingface dataset:
Protein: ARSK_CANLF
Sequence: MLLLWLSVFAASALAAPDRGAGGRRRGAAGGWPGAPNVVLVVSDSFDGRLTFYPGSQAVKLPFINLMKAHGTSFLNAYTNSPICCPSRAAMWSGLFTHLTESWNNFKGLDPNYTTWMDIMEKHGYRTQKFGKLDYTSGHHSISNRVEAWTRDVAFLLRQEGRPMINLIPKKTKVRVMEGDWKNTDRAVNWLRKEASNSTQPFVLYLGLNLPHPYPSPSSGENFGSSTFHTSLYWLKKVSYDAIKIPKWSPLSEMHPVDYYSSYTKNCTGKFTKKEIKNIRAFYYAMCAETDAMLGEIILALRQLDLLQNTIVIYTSDHGELAMEHRQFYKMSMYEASAHIPLLMMGPGIKANQQVSNVVSLVDIYPTMLDIAGAPLPQNLSGYSLLPLSSEMFWNEHKLKNLHPPWILSEFHGCNVNASTYMLRTNQWKYIAYSDGTSVLPQLFDLFSDPDELTNIATKFPEVTYSLDQKLRSIINYPKVSASVHQYNKEQFIKWKQSVGQNYSNVIANLRWHQDWLKEPRKYESAINQWLKTPH
What is the function of this protein?
Catalyzes the hydrolysis of pseudosubstrates such as p-nitrocatechol sulfate and p-nitrophenyl sulfate (By similarity).  Catalyzes the hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate (By similarity).  Acts selectively on 2-sulfoglucuronate and lacks activity against 2-sulfoiduronate (By similarity).
What are the official names of this protein?
Arylsulfatase K, ASK, Glucuronate-2-sulfatase.
What is the protein family that this protein belongs to?
Belongs to the sulfatase family.
What are the subcellular locations of this protein?
Secreted. Lysosome.
Protein: IL6_CAPHI
Sequence: MNSLFTSAFSPLAVSLGLLLVMTSAFPTPGPLGEDFKNDTTPSRLLLTTPEKTEALIKHIVDKISAIRKEICEKNDECENSKETLAENKLKLPKMEEKDGCFQSGFNQAICLIKTTAGLLEYQIYLDFLQNEFEGNQETVMELQSSIRTLIQILKEKIAGLITTPATNTDMLEKMQSSNEWVKNAKVIIILRSLENFLQFSLRAIRMK
What is the function of this protein?
Acts as an essential factor in bone homeostasis and on vessels directly or indirectly by induction of VEGF, resulting in increased angiogenesis activity and vascular permeability.  Induces, through 'trans-signaling' and synergistically with IL1B and TNF, the production of VEGF.  Involved in metabolic controls, is discharged into the bloodstream after muscle contraction increasing lipolysis and improving insulin resistance (By similarity).  'Trans-signaling' in central nervous system also regulates energy and glucose homeostasis.  Mediates, through GLP-1, crosstalk between insulin-sensitive tissues, intestinal L cells and pancreatic islets to adapt to changes in insulin demand (By similarity).  Also acts as a myokine (By similarity).  Plays a protective role during liver injury, being required for maintenance of tissue regeneration (By similarity).  Also has a pivotal role in iron metabolism by regulating HAMP/hepcidin expression upon inflammation or bacterial infection (By similarity).  Through activation of IL6ST-YAP-NOTCH pathway, induces inflammation-induced epithelial regeneration (By similarity).
What are the official names of this protein?
Interleukin-6, IL-6.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TOLB_ECO7I
Sequence: MKQALRVAFGFLILWASVLHAEVRIVIDSGVDSGRPIGVVPFQWAGPGAAPEDIGGIVAADLRNSGKFNPLDRARLPQQPGSAQEVQPAAWSALGIDAVVVGQVTPNPDGSYNVAYQLVDTGGAPGTVLAQNSYKVNKQWLRYAGHTASDEVFEKLTGIKGAFRTRIAYVVQTNGGQFPYELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLAYVTFESGRSALVIQTLANGAVRQVASFPRHNGAPAFSPDGSKLAFALSKTGSLNLYVMDLASGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYKVNINGGAPQRITWEGSQNQDADVSSDGKFMVMVSSNGGQQHIAKQDLATGGVQVLSSTFLDETPSLAPNGTMVIYSSSQGMGSVLNLVSTDGRFKARLPATDGQVKFPAWSPYL
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.  TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CWC25_ASHGO
Sequence: MDLNLLKSWNPQLQKNRKKVYEAQQELLKSARKPADDGTSGGGLDWMYEGQPAPQRKVRKRRTRTRKPKQVPKDAQGKLQESLQTARSDAPEGTCSPDETAAARGGQQGAPVEVSAKSPAKAVAEARGGPGSSGVHGE
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor CWC25.
What is the protein family that this protein belongs to?
Belongs to the CWC25 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VPP_BPHC1
Sequence: MAEHKLRKRKTSRYDDEVIYAAKFLYLKKYTPKEIAEELGLNSRRPIYYWAEKYNWRNLLSESGIEELIALRIITLTERENKSDQEIKELEALIDKDIQYKKQRAATVAKVTAKSAVNSADVSGNERAFADSGDGDERKKKKRVKNDISHVTPEMCQPFIDSLFDYQKHIRSNKHHDVRNILKSRQIGATYYFSFEALEDAIFSGDNQIFLSASKRQAEIFKNYIVKMAREYFGVELTGNPIILSNGAELHFLSTNKNTSQGNSGHVYGDEYAWIRDFQRFDDVASAMATHEKWRETYFSTPSSKFHESYSFWSGDNWRDGDPKRKNVPFPTFAELRDGGRLCPDGQWRYVVTIEDALKGGADKLFNIEKLKQRYSKYAFNQLYMCIWIDDADSIFNVKQLLKCGVDIAKWKDFNPKADRPFGDREVWGGFDPAHSGDGASFVIIAPPALPGEKYRMLARYQWHGLSYVYQANQIRALYEKYNMTYIGIDATGVGYGVYELVKEFARRAATAIIYNPESKTGMVLKVHDLVEHGQIEWSESELDIVPSFLMIKHQSTKSGNTMTFTAERTVKTQHADVFFAICNAINKKSLSDKPRKRRRWSVLNEN
What are the official names of this protein?
Probable terminase, ATPase subunit, ORF16.
What is the protein family that this protein belongs to?
To phage P2 protein P.
Protein: Y2389_STAAR
Sequence: MEKVYVAGAIPEVGLKLLQEHFEVEMYEGKGLVDKDTLIKGVKDATALISLLSTNVDKDVIDAGKDLKIIANYGAGFNNIDIEYAREKSIDVTNTPKASTNATADLTIGLVLAVARRIVEGDQLSRTTGFDGWAPLFFRGREVSGKTIGIIGLGEIGSAVARRARAFDMDVLYTGPNRKEEKEREIGAKYVDLDTLLKNADFITINAAYNPKMHHLIDTEQFKMMKSTAYLINASRGPIVHEQALVQALKNNEIEGAALDVYEFEPDITDDLKSLNNVVLTPHIGNATFEARDMMSKIVANAAISAVQGEKPQFVVN
What are the official names of this protein?
Putative 2-hydroxyacid dehydrogenase SAR2389.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Protein: RAE1E_HUMAN
Sequence: MRRISLTSSPVRLLLFLLLLLIALEIMVGGHSLCFNFTIKSLSRPGQPWCEAQVFLNKNLFLQYNSDNNMVKPLGLLGKKVYATSTWGELTQTLGEVGRDLRMLLCDIKPQIKTSDPSTLQVEMFCQREAERCTGASWQFATNGEKSLLFDAMNMTWTVINHEASKIKETWKKDRGLEKYFRKLSKGDCDHWLREFLGHWEAMPEPTVSPVNASDIHWSSSSLPDRWIILGAFILLVLMGIVLICVWWQNGEWQAGLWPLRTS
What is the function of this protein?
Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.
What are the official names of this protein?
Retinoic acid early transcript 1E, Lymphocyte effector toxicity activation ligand, NKG2D ligand 4, N2DL-4, NKG2DL4, RAE-1-like transcript 4, UL16-binding protein 4.
What is the protein family that this protein belongs to?
Belongs to the MHC class I family.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 4]: Secreted.
Protein: FER2_EQUTE
Sequence: AYKVTLKTPDGDITFDVEPGERLIDIASEKADLPLSCQAGACSTCLGKIVSGTVDQSEGSFLDDEQIEQGYVLTCIAIPESDVVIETHKEDEL
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin-2, Ferredoxin II.
What is the protein family that this protein belongs to?
Belongs to the 2Fe2S plant-type ferredoxin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PYRI_METBF
Sequence: MKEKRDLKIQAIENGTVIDHIKAGQALNVLRILGISSAFRATISFVMNAPGAAGIKDVVKIEGKELSVEELNRIALISPKATINIIRDFKVVQKNKVVLPSYVEGVVRCINPNCISNSSEPIKSKFSVLQSEEEGVTLNCLYCEHVISENIAENLL
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: OGG1_SACS2
Sequence: MLRSLVQNPKVRARVLERVDEFRLNNLSNEEVWFRELTLCLLTANSSFISAYQALNCLGQKIYYANEEEIRNILKSCKYRFYNLKAKYIIMAREKVYGRLKEEIKPLADEDQQLARERLLNIKGIGMKEASHFLRNVGYFDLAIIDRHIIDFMRRIGAIGETNVKQLSKSLYISFENILKSIASNLNMSVGILDLFIWYKETNTIVK
What is the function of this protein?
Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA.  Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites).
What are the official names of this protein?
8-oxoguanine DNA glycosylase/AP lyase.
What is the protein family that this protein belongs to?
Belongs to the type-2 OGG1 family.
Protein: FAHD2_DICDI
Sequence: MNRANFGLIKLVTYIPNVGEQSKRLGALLENSIIDLCSADKSIPNDMRSFLSLNSTDKWSKVINVINNINNRRIPIENCKIKAPIEPGKIICIGLNYKEHANEAKMAIPKEPIVFSKFDNAICGPNDSIIKPVESDEVDYEVELVVVIGKQAKNVSESDALQYVAGYTVGNDVSARDWQLRKNNSQWLLGKTFDTFAPIGPSIVINPEVAALSDDTYFDPNNLSIKCTLNGQVVQNSTTKEFIFNIQTVVSYLSKLFTLNPGDIIFTGTPSGVGFIRKPNPIFLKSGDVIKCEIEELGSLVNNVK
What is the function of this protein?
May have hydrolase activity.
What are the official names of this protein?
Fumarylacetoacetate hydrolase domain-containing protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the FAH family.
Protein: TRX2_EHV1B
Sequence: MASAAFEIDILLPSDLSPADLSALQKCEGKLVFLTALRRRVMLSSVTLSSYYVNGAPPDTLSLMAAFRRRFPAIIQRVLPNKMIAAALGVAPLPPGAFIQNTGPFDLCNGDSVCALPPILDVEDKLRLGSVGEEILFPLTVPLAQARELIARLVARAVQALTPNAQAQRGAEVMFYNGRKYNVTPDLRHRDAVNGVARSLVLNMIFAMNEGSLVLLSLIPNLLTLGTQDGFVNAIIQMGSATREVGQLVHQQPVPQPQDGARRFCVYDALMSWISVASRLGDVVGGKPLVRICTFEGQATISRGEKAPVIQTLL
What is the function of this protein?
Structural component of the T=16 icosahedral capsid.  The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes.  These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2.  Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.
What are the official names of this protein?
Triplex capsid protein 2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRX2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: RS15_LISMO
Sequence: MALTQERKNEIIAEYRVHDTDTGSPEVQIAVLTAEINSLNEHVRVHKKDHHSYRGLMKMVGHRRNLLTYLRKKDVQRYRELIKRLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: CDK1_CANAL
Sequence: MVELSDYQRQEKVGEGTYGVVYKALDTKHNNRVVALKKIRLESEDEGVPSTAIREISLLKEMKDDNIVRLYDIIHSDSHKLYLVFEFLDLDLKKYMESIPQGVGLGANMIKRFMNQLIRGIKHCHSHRVLHRDLKPQNLLIDKEGNLKLADFGLARAFGVPLRAYTHEVVTLWYRAPEILLGGKQYSTGVDMWSVGCIFAEMCNRKPLFPGDSEIDEIFRIFRILGTPNEEIWPDVNYLPDFKSSFPQWKKKPLSEAVPSLDANGIDLLDQMLVYDPSRRISAKRALIHPYFNDNDDRDHNNYNEDNIGIDKHQNMQ
What is the function of this protein?
Cyclin-dependent kinase that acts as a master regulator of the mitotic and meiotic cell cycles (By similarity).  May drive the G1-S transition (PubMed:7830719).  Plays a role in mitotic exit (PubMed:22090345).  Plays a role in the expression of morphology-related transcription factors, and especially hyphae-specific genes (PubMed:16710830, PubMed:11809828, PubMed:15659158).  Binds distinct cyclin subunits as cells progress through the division cycle or flamentous growth (PubMed:15071502, PubMed:17765684, PubMed:18923418, PubMed:22787279).  The CDC28-CLB2 complex regulates cytokinesis partly by phosphorylating the actomyosin ring component IQG1 (PubMed:18923418).  The CDC28-CLN3 complex phosphorylates SLA1 which regulates cortical actin patch dynamics (PubMed:22787279).  The CDC28-CCN1 complex phosphorylates CDC11 and SEC2 upon induction of filamentous growth (PubMed:17765684).  The CDC28-HGC1 complex also phosphorylates SEC2 and maintains CDC11 phosphorylation throughout hyphal growth (PubMed:20639857).  Moreover, the CDC28-HGC1 complex phosphorylates and prevents RGA2 from localizing to hyphal tips, leading to localized CDC42 activation for hyphal extension (PubMed:17673907).  CDC28-HGC1 phosphorylation of EFG1 represses cell separation genes during hyphal growth (PubMed:19528234).  Additional substrates for CDC28 are RFA2 in G1-phase; MOB2, which is required for the maintenance of polarisome components and for inhibition of cell separation in hyphae; and GIN4 to regulate its association to SEP7 and subsequent septin ring assembly (PubMed:23140133, PubMed:22366454, PubMed:21593210).
What are the official names of this protein?
Cyclin-dependent kinase 1, CDK1, Cell division control protein 28, Cell division protein kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Protein: RUVC_PSEP1
Sequence: MTLILGIDPGSRITGYGVVRQTARGCEYVASGCIRTGSGELHERLQIVFRGVSEIIAQHGPVTMGIERVFMARNADSALKLGQARGAAIVAAAEAGLEIAEYSATQVKQAVAGTGGANKEQVMMMVMHLLKLTQKPQIDASDALAIALCHAHTRSSLVPHGLSTARRRGGRLRL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: KUP_ECOSE
Sequence: MSTDNKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGFGVERDAVFGFLSLIFWLLIFVVSIKYLTFVMRADNAGEGGILTLMSLAGRNTSARTTSMLVIMGLIGGSFFYGEVVITPAISVMSAIEGLEIVAPQLDTWIVPLSIIVLTLLFMIQKHGTAMVGKLFAPIMLTWFLILAGLGLRSIIANPEVLHALNPMWAVHFFLEYKTVSFIALGAVVLSITGVEALYADMGHFGKFPIRLAWFTVVLPSLTLNYFGQGALLLKNPEAIKNPFFLLAPDWALIPLLIIAALATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMESGQIYIPFVNWMLYVAVVIVIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARQNWHWNKYFVALILIAFLCVDIPLFTANLDKLLSGGWLPLSLGTVMFIVMTTWKSERFRLLRRMHEHGNSLEAMIASLEKSPPVRVPGTAVYMSRAINVIPFALMHNLKHNKVLHERVILLTLRTEDAPYVHNVRRVQIEQLSPTFWRVVASYGWRETPNVEEVFHRCGLEGLSCRMMETSFFMSHESLILGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI
What is the function of this protein?
Responsible for the low-affinity transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Low affinity potassium transport system protein Kup, Kup system potassium uptake protein.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MTS1_STRAH
Sequence: MNHELPVISLFSGAGGLDCAIESCAEPPLVQDGSGSPLRVAVATDYEQTALDTLSANFPHTKTLCGDIQTIPTAELLEAGGLKPGDPTLVIGGPPCTPFSKSGFWIEEKRNSADPNASLLDEYVRVVRESKPEAFILENVQGLTYKTHQAQFDRLIAGLKDAGYNPTFRVLLAAEYGVPQLRRRVFVVGRRDGKAFHFPETTHSGESERDRVIDHTKIPFTSLREALAGLPDVPEAGEVVEGTYAELAAEVPPGQNYLWHTDRYGGRNEFKWRSRYWTFLLKADPDRPSTTLQAQPGPWVGPFHWENVKNANGEERARRFRVAEMKRIMTFPDEFVFTGVKREVQRQIGNPVPVELGKVVVRALMEQLGYLDSRGTTIPSQAGHEQLELI
What is the function of this protein?
A beta methylase recognizes the double-stranded sequence 5'-GAGCTC-3', methylates C-4 on both strands, and protects the DNA from cleavage by the SacI endonuclease.
What are the official names of this protein?
Type II methyltransferase M.SacI, M.SacI, Cytosine-specific methyltransferase SacI, Modification methylase SacI.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Protein: PSD_RUEST
Sequence: MNMIGTFIKPMHPEGRKFVAIFAAVTFGLFLLTPILGWIGVGLTVWCYYFFRDPERVTPARPGLVISPADGVVSLIEPAVPPAELGLPDVPLTRVSVFMSVFNCHVNRAPVAGEVTAVAYRPGKFFNASLDKASADNERNSLAIRMEDGRDLAVVQIAGLVARRIVCFVKPGAQLGRGERFGLIRFGSRLDVYLPEGVSPQVEIGQTMIAGETVIAELGTGVHTDQNKGELHG
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SYY2_BACCR
Sequence: MNIIDELEWRGAVNQQTDEEGLRKLVEEKKISLYCGVDPTGDSMHIGHLIPFMMMKRFQLAGHHPVILIGGATGTIGDPSGRQSERQLQTLEVVQHNVDALTAQMKKLFDFGGNSEVKMVNNYDWTHEINIIEFLRDYGKNFSINSMLAKDIVASRLDTGISFTEFTYQILQAMDFHHLYTKEDVQLQIGGSDQWGNITSGLDLIRKLEGHEAKVFGLTIPLLLKSDGTKFGKSAGGAVWLDPEKTTPFEFYQFWVNTDDRDVIKYLKYFTFLTKERIDELATKVEVEPHKREAQKVLAEEMTKFVHGEEAFLQAEKITAALFSGDIKSLTADEIEQGFKEMPTFQSSKETKNIVEWLVDLGIEPSRRQAREDINNGAISMNGEKVTDVGTDVTVENSFDGRFIIIRKGKKNYSLVKLGE
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase 2, Tyrosyl-tRNA synthetase 2, TyrRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCDC7_HUMAN
Sequence: MKPVKHLLTTSNKSANVPALTTKKGLHNLPLSPELKEKHNAKLIHDKIEPMVLRSPPTGESILRYALPIPSSKTKNLLPEDEMIGKIIKHLKMVVSTLEETYGHCDQNGEEPFVKHEHEELSLSVGDDMNSFLTYCSQFAAQLEEALKEEQNILESLFKWFQWQVNQMEEISKDQTLLQAEPPKPDKTVILNIAEIVRLVQRFEELKNRLKQRSKSSVKVMLSKTMDKENRPEAVKSCEALAQKIEEFLEAHSTDEFKDVSATEPQTAHSMTNRFNAMLKVFENQANMLERAVNDQVLLDAEYKQMQCDFQLLSEEKLVLENELQKLKDKEKTKPTNNRTKKAVKTVKKKDKGKSEDSEKKMSPEKEFKIKEDLDQVQKVARLEIENKVLQEQLKQALQEAEKAKHQLNYFLNQEKLLKSEGKTETTMQVGNSQTKVKGEDSKNIPLEKETRKSLVSDSGGQRTSDKIQEYPQITAQSGRLIEKSSEKKRSSPAISDLSQILKSQDESAFLESSNEVSVAENQSYKSPSETHDKSLTTVSSSKEVQDSLSVGTLAQKNETVISPFILPPVLTESKKADVSEEQLQKMTEEQTYQAAEKSQADSEVPDENLMVENKDSVTKVQIEQMKQRTSSMERHEETLTTPQLPEDMVLVSRIQSETKNLKATRNESFHSHNDVPEENLMLEQDTKSKTEVEVKKQKSFQDNQLSTHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLILRHQDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKLPREKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKLQMQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFPLEIKKKDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKIKNEAASELPDTAENLPAMYPSISDLIIQFDLNKVVETDIESLRGALGRRLLNDEFKTQSKSFPGPDIEQLTDAFGRDILKDEFKTRSKSLPETDERLHSTTERGTINDAIKTQLKRKSYPETVLKHLKGVNGKDIIKHLINIQSKSHGETDKEHLADDTGRGIIKGSINAQLKGHQKTDKNFFAYATGRGLMKESTTTQLKSHPETDKEFLADAIGRGIIIGPITTQLKSHRETDKELLKDAIGRDIIKGPISAQLKSHQETDVEPLTNAIGSSKTIGEIKTQLRTHYDVNLFKNKDMSVQRQEGIFTRSITPSKFPTKVINLSPFENKEETYEYSSPYVTAPSKAIYRTYRAGPSFSKDIHLPLLNQLPSGHSKVVTLSQKTIEFTLPTVTNTVGKPTYKVLHAAARKSVPHPYF
What is the function of this protein?
May play a role in tumorigenesis.
What are the official names of this protein?
Coiled-coil domain-containing protein 7, Protein BIOT2.
Protein: IF1A_METS5
Sequence: MPKKDRTDQAPSKDVPKPEEGEVICVVKKMLGAEHIIIACLDGKERTARIPGRMRKKTWIKEGDVVLAAPWDFQPTKADIVYRYMNDEIRKLIEEKVISRDVIDQLRG
What is the function of this protein?
Seems to be required for maximal rate of protein biosynthesis.  Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
What are the official names of this protein?
Translation initiation factor 1A, aIF-1A.
What is the protein family that this protein belongs to?
Belongs to the eIF-1A family.
Protein: CCPB_BACSU
Sequence: MANIKEIARLANVSVSTVSRVLNHHPYVSEEKRKLVHQVMKELDYTPNRTAIDLIRGKTHTVGVILPYSDHPCFDKIVNGITKAAFQHEYATTLLPTNYNPDIEIKYLELLRTKKIDGLIITSRANHWDSILAYQEYGPVIACEDTGDIDVPCAFNDRKTAYAESFRYLKSRGHENIAFTCVREADRSPSTADKAAAYKAVCGRLEDRHMLSGCNDMNDGELAAEHFYMSGRVPTAIYANSDEVAAGIHLFAKKNNWDVEIIGEGNTSISRVLGFPSLDLNLEQLGIAAFSLFLQDEPADIKIQHKFKKKA
What is the function of this protein?
Transcriptional regulator involved in catabolite repression of several operons.
What are the official names of this protein?
Catabolite control protein B.
Protein: PGTB1_ARATH
Sequence: MSETAVSIDSDRSKSEEEDEEEYSPPVQSSPSANFEKDRHLMYLEMMYELLPYHYQSQEINRLTLAHFIISGLHFLGARDRVDKDVVAKWVLSFQAFPTNRVSLKDGEFYGFFGSRSSQFPIDENGDLKHNGSHLASTYCALAILKVIGHDLSTIDSKSLLISMINLQQDDGSFMPIHIGGETDLRFVYCAAAICYMLDSWSGMDKESAKNYILNCQSYDGGFGLIPGSESHGGATYCAIASLRLMGYIGVDLLSNDSSSSIIDPSLLLNWCLQRQANDGGFQGRTNKPSDTCYAFWIGAVLKLIGGDALIDKMALRKFLMSCQSKYGGFSKFPGQLPDLYHSYYGYTAFSLLEEQGLSPLCPELGLPLLAAPGI
What is the function of this protein?
Negatively regulates ABA signaling in guard cells.  in negative regulation of auxin-induced lateral root initiation.
What are the official names of this protein?
Geranylgeranyl transferase type-1 subunit beta, Geranylgeranyl transferase type I subunit beta, AtGGT-IB, GGTase-I-beta.
What is the protein family that this protein belongs to?
Belongs to the protein prenyltransferase subunit beta family.
Protein: TDRD5_DANRE
Sequence: MTQDQLLAGLKKDVRSLLVSSKHGLTPEHLRRDYQSMLGFPMPLRLLGFRNVLDMVKEMPEVVRLEYQLDGNIILKAIGDDTTKGIEELVSKQRDHKPKPNNRKGKPGYFNISYPRLQPVILPRRGQAKPALPAHLRSQLKQLLSHGPVRLSELESRYVAQFGKPLNVTQYGFFSISEMLSAAMDFIIMQQSRTGSQLLLRSAVTPQNQPENLMRRFSMQSTSPKQRLAGFSPKASSLPERRPEVSLDPSSVSKPEPVKEEQSFEETVFKLEEELRQQILEKGTAGTVSQELKEKLRKVVAENGNGISIHNLPTEYQRMHGEELPVSQCGFLSVTEMVGALSDTLAIQRGTDESESHWMVVEFKPIDTQPCEPELSPGDGTTSSPTGELQNPSSRAFYFSCPESAWEHEETEPLTDSQESDAELRVANKTIHQMVNLFPELMVSRVSAVPLDAVRCQKLKPPVHRKERELLPVLVEQTESPSYFYIRFSQNKEARALENMMIEMRSCYSYPDVAERYRLPDAYVRPGQVCCVAPRDMWFYRVVIHEVFSETEVKVYYVDYGDITKVERHSLRFLKACYADLPAQAVPAMLAGVRPITNIWPASAVSCFQRLCCERTLVAGVHSYQEDFLLLFLCDTNTEEDVYVHLALIQEGHAQPCSAAYGLVSEKFNPVTSYFGYDQLEDVKESLSPFSCSPDAEIDSQGNDSPSSCRTASNSESGETNLASIDVDPNLDLPPLEVINVPDVNTAAKSENVNPFEALVRKDPLFNSEWDQGWTAEDKTDETKFELDVSTEQSKPETVYTPSPVQAAVGKQQLCASPVEPKVNATTCVNPHNPVPIQINCSYPVLPGVPVYPVKPPISQFMMQLLGNPVYQGPGPNTAFQHLTSPLALRPAARMSAGGQILHWS
What is the function of this protein?
Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity.  Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons (By similarity).
What are the official names of this protein?
Tudor domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the TDRD5 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to chromatoid body (CB) and pi-body (also called intermitochondrial cementin), 2 cytoplasmic ribonucleoprotein granules involved in RNA processing for spermatogenesis.
Protein: KAD_ANADF
Sequence: MILILLGPPGAGKGTQAKLLAAEYGVPHISTGDMFRDHKARGTELGKTVQAIMDAGGLVTDDITNEMVKDRLSRPDVAKGFILDGYPRTSAQAEYLDGLLASAGRAISRVLSYEVAEEAVVERISGRRSCPKCGAVYHVSANPPRRMGYCDRDDAGLVQRDDDKPENVKKRMAEYAAKTEPLKRFYSARGLLATVEGIGTPEGILAVTKRVLAS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.