PharMolix/UniProtQA huggingface dataset:
Protein: GUC2G_RAT
Sequence: MASRARSEPPLEHRFYGGAESHAGHSSLVLTLFVVMLMTCLEAAKLTVGFHAPWNISHPFSVQRLGAGLQIAVDKLNSEPVGPGNLSWEFTYTNATCNAKESLAAFIDQVQREHISVLIGPACPEAAEVIGLLASEWDIPLFDFVGQMTALEDHFWCDTCVTLVPPKQEIGTVLRESLQYLGWEYIGVFGGSSAGSSWGEVNELWKAVEDELQLHFTITARVRYSSGHSDLLQEGLRSMSSVARVIILICSSEDAKHILQAAEDLGLNSGEFVFLLLQQLEDSFWKEVLAEDKVTRFPKVYESVFLIAPSTYGGSAGDDDFRKQVYQRLRRPPFQSSISSEDQVSPYSAYLHDALLLYAQTVEEMMKAEKDFRDGRQLISTLRADQVTLQGITGPVLLDAQGKRHMDYSVYALQKSGNGSRFLPFLHYDSFQKVIRPWRDDLNASGPHGSHPEYKPDCGFHEDLCRTKPPTGAGMTASVTAVIPTVTLLVVASAAAITGLMLWRLRGKVQNHPGDTWWQIHYDSITLLPQHKPSHRGTPMSRCNVSNASTVKISADCGSFAKTHQDEELFYAPVGLYQGNHVALCYIGEEAEARIKKPTVLREVWLMCELKHENIVPFFGVCTEPPNICIVTQYCKKGSLKDVLRNSDHEMDWIFKLSFVYDIVNGMLFLHGSPLRSHGNLKPSNCLVDSHMQLKLAGFGLWEFKHGSTCRIYNQEATDHSELYWTAPELLRLRELPWSGTPQGDVYSFAILLRDLIHQQAHGPFEDLEAAPEEIISCIKDPRAPVPLRPSLLEDKGDERIVALVRACWAESPEQRPAFPSIKKTLREASPRGRVSILDSMMGKLEMYASHLEEVVEERTCQLVAEKRKVEKLLSTMLPSFVGEQLIAGKSVEPEHFESVTIFFSDIVGFTKLCSLSSPLQVVKLLNDLYSLFDHTIQTHDVYKVETIGDAYMVASGLPIRNGAQHADEIATMSLHLLSVTTNFQIGHMPEERLKLRIGLHTGPVVAGVVGITMPRYCLFGDTVNMASRMESSSLPLRIHVSQSTARALLVAGGYHLQKRGTISVKGKGEQTTFWLTGKDGFAVPLPEFTEEEAKVPEIL
What are the official names of this protein?
Guanylate cyclase 2G, Guanylyl cyclase receptor G, GC-G, Kinase-like domain-containing soluble guanylyl cyclase, ksGC.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
Protein: APRL4_ARATH
Sequence: MEKEILLLLLVIMFLTVADVDAVRVPFCATKSAKDSIFGLRDQTCSVSGVESDERPRFVAVTEGDERWLQIALDMIHKNKCDYVALLFYASWCPFSRSFRPSFDVISSLYSSIPHFAIKESSIKPSTLSKYGVHGFPTLLLLNSTMRARYRGTRMLDSLVAFYSDVTGIETLDKTSLERSVSVPHLGNENNTEPENCPFTWARSPENMLRQETYLALAIVFVLLRLLHLIYPTLVVFMKFTWRRIAQNMRLESLLEHTVGFLSRAVQLCMHRRSNLQGGAMNARAWASKSLATVSIGDSSSSNRRSSSSQ
What are the official names of this protein?
5'-adenylylsulfate reductase-like 4, Adenosine 5'-phosphosulfate reductase-like 4, APR-like 4, AtAPRL4.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MNME_BUCAI
Sequence: MRNETIVAQVTCPGKSAVGILRISGFQTKIVAIKILGKIPLARFATYSNFLDENNEILDKGISLWFPAPHSLTGEDVLELQGHGSPLIMDLLIRRILSINNIRMAKPGEFSERAFLNGKMDLIQAESIDDLINSETELSARASLNSLQGKFSFFIKELMNLIIEFRINIESNIDFSEEEININMQDIINIKFRELHDKFLKLKATVLKGSLLREGKKIVIAGLPNSGKSSLLNILSYSDRAIVTDIPGTTRDLLYEDISINGVRCELIDTAGLRDTDDKVERIGIMRAWEMIRKSDHVLFVIDKTLSKSKQKKICDDFMKNILNNKTQVTFVLNKNDLIKDEFGIKEIDGTAFISISARTGEGVNILREHIIKIEKNINNESVFIARRRHIKQLDLAYDEFLTAENTWRESENIELLAESLSIISKFLGEIIGQCTSEDLLNHIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUTC_CAEEL
Sequence: MTETESQKQIKLEICIDNLESAENAVAGGADRLEVCSALQLGGLTPSVGFVSILSYKYPDIPLYCMIRQRAGDFVYNEDEMAANMEDVEWLKKAGATGFVFGALTSAGSLDRTSCQSIIETARPHPVTFHRAIDVAYDWKTCLEDAIDVGFKAVLTSGQEPSALDGVYIIREMQELHKGKIDVLAGCGVNSSNVANLVEWTKCHWYHASASVAKKNAPLNKVSMGKQDNQPSRVTSLEEVRMLKATLAPV
What is the function of this protein?
Involved in copper homeostasis.  Affects body morphology and length, egg laying and brood size.
What are the official names of this protein?
Copper homeostasis protein cutC homolog.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
Protein: ALDC_METCA
Sequence: MAIDDIFIQAFRTHQQKGDLFHPLGHEDHEVFQSSTIGALMEGVYDGDTTYGELARHGDFGLGTFNALDGEMIALGGRFFQIKSDGKAYPVPPTAKTPFAVVTLFDPTVQVVWPDPIDWKQFQAAVDKAVPSKNVFYAIRVRACFDHIRVRTVPRQRKPYPPLVEVARRQPEFEYGHLEGTLVGFRFPDYTQGVNVAGYHVHFLDKAETLGGHVLDFSMRNAVVDIDVTSQFRMEVPECGAFLDADLARNQDEAIHEAEN
What is the function of this protein?
Converts acetolactate into acetoin.
What are the official names of this protein?
Alpha-acetolactate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the alpha-acetolactate decarboxylase family.
Protein: TRPD_ACIBY
Sequence: MNIQQALNHITKNIHLTQPQMEEIMRSIMQGEATEAQIGALMMGLRMKGESIDEMTAAARVMREFAIKIDVSDIKHLVDIVGTGGDGQNLFNVSTASSFVIAAAGATIAKHGNRGVSSKSGSSDLLEQAGIHLDLDMQQTERCIREMGVGFLFAPNHHKAMKYAAGPRRELGIRSIFNLLGPLTNPAGVKRFVIGVFSDELCRPIAEVMKQLGAEHVMVVHSKDGLDEISLAAPTTIAELKDGEITEWTLNPEDVGIESQTLNGLVVADATASLKLIKDALSKNKSDIGEKAANMIALNAGAGIYVAGITKTYAQAVAFAQDIIYGGQALEKMSVLAEFTKTLKQSQAD
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: AROB_CITBB
Sequence: MIAEKIRVALDERSYDIEMGAGNLDRIGSLCREVGLSGTAAVVSNTTVAPLYYETVRLSMERAGYRVVPVTLPDGEGYKNSATLNLIYDGLVDASLDRGSFILALGGGVIGDMAGFAAASYLRGIPFVQIPTTLLSQVDSSVGGKTGINHPRGKNLIGAFYQPKAVLIDVATLDTLPKREFLSGLGEIVKYGAVLDGGFFDFLEKNAKLLLARDKEALIQAVSRSCAIKAKVVAEDEREGGVRAVLNYGHTLGHAVETLTGYTRYLHGEAVAIGMVQAARLSQHYGFCSQADRERIEALVVALGLPTELPSFPPQQYREALSHDKKVRDKGLLFICNQGIGAYRMERLTDLGALLEICGIGE
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_DESHD
Sequence: MHILLTNDDGYFAPGLQTLYTTLAEAGYDVFIVAPDSQKSATGHSITLFEPLFITKHSLDRGTGYAVSGKPADCVKLAIQGSIIPKPDLVISGINNGPNLGTDVFYSGTVSAAMEGVLLGVPAIAVSLASFSAVDYKPAAQFVALSLPKLRLGPGLININIPPLPEKEWKGVRVTKLGKAVYENVFEHRQAPYGRDYYWQAGTVSPEVDQETDLYAVQEGYVSITPMHSDLTDYIKLKELRQSLSLENPNK
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THII_ECOL6
Sequence: MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVVRHWDNIEVRAKDENQRLAIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALVQYRDQLEGKTFCVRVKRRGKHDFSSIDVERYVGGGLNQHIESARVKLTNPEVTVHLEVEDDRLLLIKGRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEIGVRQVAHYLWNRFGSSHRVRFVAINFEPVVGEILEKIDDGQMGVILKRMMVRAASKVAERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTEDFARTMPEYCGVISKSPTVKAVKSKIEAEEEKFDFSILDKVVEEANNVDIREIAQQTEQEVVEVETVNGFGPNDVILDIRSIDEQEDKPLKVEGIDVVSLPFYKLSTKFGDLDQSKTWLLWCERGVMSRLQALYLREQGFNNVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLA_CRODU
Sequence: MGRFIFVSFGLLVLFLSLSGTGAGLHCPSDWYYYDQHCYRIFNEEMNWEDAEWFCTKQAKGAHLVSIKSAKEADFVAWMVTQNIEESFSHVSIGLRVQNKEKQCSTKWSDGSSVSYDNLLDLYITKCSLLKKETGFRKWFVASCIGKIPFVCKFPPQC
What is the function of this protein?
Snake venom lectin that activates platelets by binding to the platelet collagen receptor glycoprotein VI (GP6) (PubMed:9153205).  The indirect activation of integrin alpha-IIb/beta-3 (ITGA2B/ITGB3) also induced by the toxin is upstream the cytoskeletal translocation of GPIb, FcRgamma (FCER1G) and 14-3-3zeta (YWHAZ)(PubMed:16102113).
What are the official names of this protein?
Snaclec convulxin subunit alpha, CVX-alpha.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: SECM_ECO27
Sequence: MSGILTRWRQFGKRYFWPHLLLGMVAASLGLPALSNAAEPNAPAKATTRNHEPSAKVNFGQLALLEANTRRPNSNYSVDYWHQHAIRTVIRHLSFAMAPQTLPVAEESLPLQAQHLALLDTLSALLTQEGTPSEKGYRIDYAHFTPQAKFSTPVWISHAQGIRAGPQRLS
What is the function of this protein?
Regulates secA expression by translational coupling of the secM secA operon.  Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation.
What are the official names of this protein?
Secretion monitor.
What is the protein family that this protein belongs to?
Belongs to the SecM family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Periplasm. Note=The active form is cytosolic, while the periplasmic form is rapidly degraded, mainly by the tail-specific protease.
Protein: KDSB_BURP6
Sequence: MTSPLPFVAVVPARLASTRLPNKPLADLGGKPMVVRVAERAREAGAQQVLVASDAQRVLDAVREHGFDAVLTRADHPSGTDRLAEVAAKLGFDDDTIVVNVQGDEPLIDPQLVRDVASHLAAHPSCAIATAAHPIHEAHEVFNPNYVKVVLDAHGVALYFSRAPIPWSRDAYLPHWPNVAAMPAPTCPVYRHIGLYAYRARFLRTYPTLAQAPIEAAEQLEQLRAMWHGERIAVRVTEHAPEAGIDTPADLERVQALFRSRAK
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBB_BAUCH
Sequence: MNQIIFSQFGTPIERVEIALQALRHGRGVLVLDNEDRENEGDMIFAAEKMTIEQMALAIRYGSGIICLCLTEERRQQLELPMMVEHNTSHYQTAFTVTIEAAEGVTTGVSAADRITTIRTAIKNDAIPEDLNRPGHVFPLLAQPGGVLNRGGHTEAAIDLTLLAGLKPAGVLCEVTNEDGSMARALEIIAFSNQHNMPVLTINDLVAYRSR
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: GL34_ARATH
Sequence: MKFFVVIVFCAIFLSVSGDSDNMQDTCPTAPGEQSIFFINGYPCKNPTKITAQDFKSTKLTEAGDTDNYLQSNVTLLTALEFPGLNTLGLSVSRTDLERDGSVPFHSHPRSSEMLFVVKGVVFAGFVDTNNKIFQTVLQKGDVFVFPKGLLHFCLSGGFEPATAFSFYNSQNPGVVNIGEVFGIDQEHIKIMTRCLATGSGCRVTDGDEL
What is the function of this protein?
May play a role in plant defense.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Germin-like protein subfamily 3 member 4.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: HSLU_YERP3
Sequence: MSEMTPREIVSELDSHIIGQDKAKRAVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDAAVKMVRHQSIEKMRYRAEELAEERILDVLIPPAKNNWGVPDESQEPSATRQTFRKKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTNQLQSMFQNIAGQKQKPRKIKIKEALKLLIEEEAAKLVNPEELKQQAIDAVEQHGIVFIDEIDKICKRGQTSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQVSSPSDLIPELQGRLPIRVELQALTTDDFERILTEPSASLTEQYKALMATEGVTIEFTREGIRKIAEAAWQVNERTENIGARRLHTVLERLMEDISYDASESSGQSITIDAEYVGKHLDELVADEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCB2_PIG
Sequence: IPAAPVAAQARKLLRDLAFRPPLLAARSQVVQLTPRRWLNLQEYQSKKLMSDNGVKVQRFFVADTANEALEAAKRLNAKEIVLKAQILAGGRGKGVFSSGLKGGVHLTKDPEVVGQLAKQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRSCNGPVLVGSPQGGVDIEEVAASNPELIFKEQIDIIEGIKDSQAQRMAENLGFLGPLQNQAADQIKKLYNLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSENEPIENEAAKYDLKYIGLDGNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKESQVYQAFKLLTADPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTNVHEAQNILTNSGLPITSAVDLEDAAKKAVASVTKK
What is the function of this protein?
GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial, GTP-specific succinyl-CoA synthetase subunit beta, G-SCS, GTPSCS, Succinyl-CoA synthetase beta-G chain, SCS-betaG.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family. GTP-specific subunit beta subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: OSBL9_HUMAN
Sequence: MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSMVESIKHCIVLLQIAKDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGECWVYDEPLLKRLGAAKH
What are the official names of this protein?
Oxysterol-binding protein-related protein 9, ORP-9, OSBP-related protein 9.
What is the protein family that this protein belongs to?
Belongs to the OSBP family.
What are the subcellular locations of this protein?
Late endosome membrane. Golgi apparatus, trans-Golgi network membrane. Note=Localizes at the Golgi- late endosome interface.
Protein: ACSA_HELPH
Sequence: MQLDDDLEFAKKIFNPNRAFAKQARIKNMCEYKDLVHEANEDYEHFWGELAKQKLTWFKPFDKVLNSDNAPFFKWFENGKINVSYNCIDRHLKDKKNKVAIIFEGEMGDYNVITYRKLHSEVNKTANLLKNEFNVKKGDRVIIYMPMIVESVYMMLACARIGAIHSIVFAGFSPEALRDRINDAQAKLVITADGTFRKGKPYMLKPALDKALENNACPSVEKALIVIRNAKEIDYVRGRDFVYNEMVNYQSDKCEPEMMDSEDPLFLLYTSGSTGKPKGVQHSNAGYLLWAQMTMEWVFDIRDNDNFWCTADIGWITGHTYVVYGPLACGATTLILEGTMSYPDYGRWWRMIEEYRVDKFYTSPTAIRMLHAKGENEPLKYNLESLKVLGTVGEPINPTAWKWFYEKIGNSKCSIVDTWWQTETGGHIISPLPGATPIRASCATLPLPGIHAEVLNEDGTKTKPGEQGFLCITKPWPSMVRNIWGDEKRYIDSYFSQIKLNGEYVYLSGDGAIVDENGYITIIGRTDDIVNVSGHRIGTAEVESAISKHEMVVECAVVGIPDTIKGEGLFAFVVLCDGAKCNLGESLELLKEMNHILSVEIGKIAKLDNVMYVPGLPKTRSGKIMRRLLKSIAKKEPITQDLSTLEDVNVVKEIMSIVQMEE
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: ADEC_BRUA4
Sequence: MLERMIDQGAGREPADIVLKGGRFFDLVTGELVESDIAICGDRIVGTFGNYQGKHEIDISGRIVVPGFIDTHLHIESSHVTPHEFDRCVLPQGVTTVICDPHEIANVLGAEGIKFFLDSALETVMDIRVQLSSCVPATHMETSGAELLIDDLLPFADHPKVIGLAEFMNFPGVLAKDPECMAKLKAFQGRHIDGHAPLLRGLDLNGYISAGIRTEHEATSAEEALEKMRKGMHVLVREGSVSKDLKALMPIITERHAQFLALCTDDRNPLDIADQGHLDYLIRTAIAGGVEPIAIYRAASVSAARAFGLFDRGLVAPGQRADLVVVDSLEGCHAEIVLSAGRVISEDLFAARKTVAPVGRNSVKASKVSASSFRSHSNSGKTRAIGIIPGKIITESLEFDLKVGPNGVEPDFEKDVVKIAVVERHGKNGNIATGFVHGFGLKSGAIASTVSHDSHNICVVGTSDEDIAAAANRLGEIEGGFVVVRDGKVLAEMPLPIAGLMSAEPYETVRDQLRVLRHAAEELGSVLEEPFLQLAFIALPVIPHLKITDRGLVDVDKFAFVGN
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: YTFE_YERPY
Sequence: MDYRNQSLGALAIAIPRATKLFRQHQLDFCCGGKQTLLRAANKLNLDIDALEAQLSALQTEPHSSEDWQQQPLTNLISFIISRYHDRHREQLPELVLMAEKVERVHGDKPTCPRGLAAELSAILEELTQHMYKEEQILFPMIQRGMGSQASGPIFVMEAEHDAVGQQLDVVKQLTQNVTPPEGACNTWRALYTGINEFITDLMEHIHLENNLLFPRALRGE
What is the function of this protein?
Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions.
What are the official names of this protein?
Iron-sulfur cluster repair protein YtfE.
What is the protein family that this protein belongs to?
Belongs to the RIC family. YtfE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_ECOBW
Sequence: MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSATFDDQMLVDYSKNRITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALRNRSNTPILVDGKDVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPYKNHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFLKAAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGFDNFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAYFQQGNMESNGKYVDRNGNVVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKDPATLDYVVPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELKDDKEISSHDSSTNGLINRYKAWRG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TFDE2_CUPPJ
Sequence: MCHDTAPALFPRTASTGSIDGAICALCYAGATRGPRLLVLPDIYGCNAFYRGYAAYLAEQGAGEVLLVDPFAAFGELATVTREAAFQRRHRLADRAYVEELIDFIDGQRIEGVVGFCLGGLFVFELARQQVVSRLVAYYPFPQGLENRDPLDVPFDYLPALRSRHTVIVGDDDALLGTQNLQRLQAQARANDAIDLHIMNGAGHGFLADLESPDTARAAVAKRGLRIGTTTLLGG
What is the function of this protein?
Ring cleavage of cyclic ester dienelactone to produce maleylacetate.
What are the official names of this protein?
Carboxymethylenebutenolidase 2, Carboxymethylenebutenolidase II, Dienelactone hydrolase II, DLH II.
What is the protein family that this protein belongs to?
Belongs to the dienelactone hydrolase family.
Protein: YL191_MIMIV
Sequence: MQAMKPRINHNRLDENSFYKNGHIHHVRVQDQTIGWVRRVDRSIRTTVEFVVNVLQDYLTDAECSDFDVSHNIKEYLLKIPVVKSLEEMEDYLKQIPDGNISSTLAHIVSIPLGIPIEPYDLLVTDYQDTLHSFIDKIDNQAVREYLLPKIKSLKIGYWCAYTFLPETINQFHPLYLSWLDNKRVFSPNTLQLSEETRDKLDNFLEMYDIPDIGFFSVGDNGSKIIGWDYNYYRHTFCYVNLHEASNEVRKVWEFANQHFHIDTDFEQLEQLEQLE
What are the official names of this protein?
Uncharacterized protein L191.
Protein: RS7_ANAPZ
Sequence: MSRRRRVVRRAVATEGCSGNVLLARFVNVVMHQGKKALAEKIVFGALKMAESRLQGESGIAIFNTAVANVMPKMEVRSRRVGGVTYQIPVEVREDRSTSLALRWIVKAARASRKRTNKTYMSCLCHELMEAYNKRGGACKIKEEKYRMAEANKAFSHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: CSOR_MYCBO
Sequence: MSKELTAKKRAALNRLKTVRGHLDGIVRMLESDAYCVDVMKQISAVQSSLERANRVMLHNHLETCFSTAVLDGHGQAAIEELIDAVKFTPALTGPHARLGGAAVGESATEEPMPDASNM
What is the function of this protein?
Copper-sensitive repressor that has a key role in copper homeostasis.  It is part of the cso operon involved in the cellular response to increasing concentrations of copper inside the bacterium, which can be highly toxic.  In the presence of copper, CsoR fully dissociates from the promoter in the cso operon, leading to the transcription of its genes.  Binds to a GC-rich pseudopallindromic sequence, 5'-GTAGCCCACCCCCAGTGGGGTGGGA-3', in the cso promoter region (By similarity).
What are the official names of this protein?
Copper-sensing transcriptional repressor CsoR, Copper-sensitive operon repressor.
What is the protein family that this protein belongs to?
Belongs to the CsoR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETN_PROM1
Sequence: MIFTLGWASLAAIFTFSIAMVVWGRNGDGSIDL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: HTPG_OCEIH
Sequence: MGKRKFKAESQKLLDMVINSIYSQREVFLRELISNASDAIDKIYYKALTDDSLSFDVDNYYIKITPNKEERTLTVVDTGIGMTKEELENNLGVIAKSGSHTFKSENEIKDGHDIIGQFGVGFYAAFMVADKVEVVTKSIDSDAAFKWESKGSDGYSITEADKQDIGTTITLYIKENQEEENYDEFLDTFTLQQIIKKYSDFIRYPIKMDVTESKLKEGSEDEYEDVVEEQTINTMVPIWKKNKSELTDDDYTNFYQEKRYGFDKPLKHVHINVDGSIRYNAILFIPESAPFNYYTRDYEKGLELYSNGVLIMDKCADLLPDYFSFVKGMVDSEDLSLNISREMLQHDRQLKLIAKNIKKKVKQQLVSLLRDERENYEKFFDAFGQQIKFGVYSDYGQNKDELKDLLLFYSSKEKKLVTLEEYVSCMPEDQKYIYYATGDSRDRIEKLPQTELVADKGYEILYFTDEIDEFAIKMLMNYDEKEFRSVSSGDLGIEEDEKEENEQENNDNAELFTAMKEVLSTKVKDVRASKRLKSHPVVLTADGEISLEMEKIINAMPDDQQIQADKVLEINVNHDIFQSLKAAQGNDDEKFKLYTNLLYNQALLIEGLPINDPVEFTNDICKVMV
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.