PharMolix/UniProtQA huggingface dataset:
Protein: PYRE_XANAC
Sequence: MTDHRTRFLQLALDADALRFGEFTLKSGRLSPYFFNAGRFDSGAKTAQLAQCYADAIEAAGLDFDLLFGPAYKGIPLATALACAYAGRGRDLPLAFNRKEAKDHGEGGTLIGAPLAGRQVLIVDDVITAGTAIREALAIIRAAGGTPSGIAVALDRQEIASDQDRRSAAQAVAAEAGIPVIAVANLGDLLAFAAGNADLVGFQEPLLAYRGRYGTDTTG
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: TRMYL_ALCBS
Sequence: MRTFVLRARAASTHSQTLLANVGGDAHSEILAHTLMNAIFVAQSHRDDVVVHLVLESTQDYSRTITFVAAEMRDIGGFHEQALLAKVVRALDASAGMGKEQMKAVESGITVRTQSFEKVVKELAEDGHQLYMMDPKGENIRELDFAQKPCFLLTDHIPMPKKSFNSLKRLGTEKISLGPTMLFASQCVVLINNELDLAGF
What are the official names of this protein?
Putative pseudouridine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. TrmY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU2C2_MORIN
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFDGSFIFPECILIFGLILLLMIDSTSDQKDIPWLYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKKDVRSNEATTKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNGGYASMITYMLFYISMNLGTFACIVSFGLRTGTDNIRDYAGLYTKDAFLALSLALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVSIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVQNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIIEIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 B, chloroplastic, NAD(P)H dehydrogenase, subunit 2 B, NADH-plastoquinone oxidoreductase subunit 2 B.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: HCN2_RAT
Sequence: MDARGGGGRPGDSPGTTPAPGPPPPPPPPAPLQLQPPPAPPPNPTTPSHPESADEPGPRSRLCSRDSSCTPGAAKGGANGECGRGEPQCSPEGPARGPKVSFSCRGAASGPAAAEEAGSEEAGPAGEPRGSQASFLQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNTEIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPSDCWVSINNMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHKVQHDLSSGVFNNQENAIIQEIVKYDREMVQQAELGQRVGFFPPPPPRQVRSAIATLQQAVAMSFCPQVARPLVGPLALGSPRLVRRAPPGPLPPAASPGPPAASPPAAPSSPRAPRTSPYGVPGSPATRVGPALPARRLSRASRPLSASQPSLPHGAPAPSPAASARPASSSTPRLGPAPTTRTAAPSPDRRDSASPGAASGLDPLDSARSRLSSNL
What is the function of this protein?
Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions.  Contributes to the native pacemaker currents in heart (If) and in neurons (Ih).  Can also transport ammonium in the distal nephron.  Produces a large instantaneous current.
What are the official names of this protein?
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2.
What is the protein family that this protein belongs to?
Belongs to the potassium channel HCN family.
Protein: RL7_CLOD6
Sequence: MTIEQILEAIENMKVLELNELVKAAEEKFGVSASAPVMVAGAAAGGPAAEEKTEFDVVLTDVGSSKVGVIKAVREITGLGLKEAKEVVDNAPKTVKEGASKEEADQIKEKLEAAGAKVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: HIS1_LACLM
Sequence: MIRVAMTKGRIQKQVTILLEQAGFDMTAVREMGRELVVTIPDDLEIIFGKANDVITFLEHGIVDIGFVGKDTLDENDFDDYYELLDLKVGQCIFALASYPDFLNKKFHRRKRIASKYPRITKNYFAQKQEDIEIIKLEGSVELGPVVGLADAIVDIVETGNTLSANGLVVIEKISQISTRMIVNKVSFKFKKDKIIEIVERLENAQTN
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCL2_BOVIN
Sequence: MAHAGGTGYDNREIVMKYIHYKLSQRGYEWDAGDAGAAPPGAAPAPGILSSQPGRTPAPSRTSPPPPPAAAAGPAPSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFTARERFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDSIALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKALLSLALVGACITLGAYLGHK
What is the function of this protein?
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells.  Regulates cell death by controlling the mitochondrial membrane permeability.  Appears to function in a feedback loop system with caspases.  Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).  Also acts as an inhibitor of autophagy: interacts with BECN1 and AMBRA1 during non-starvation conditions and inhibits their autophagy function.  May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release.
What are the official names of this protein?
Apoptosis regulator Bcl-2.
What is the protein family that this protein belongs to?
Belongs to the Bcl-2 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein. Nucleus membrane; Single- pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein. Cytoplasm.
Protein: GRAS_STAA1
Sequence: MNNLKWVAYFLKSRMNWIFWILFLNLLMLGISLIDYDFPIDSLFYIVSLNLSLTMIFLILTYFKEVKLYKHFDKDKEIEEIKHKDLAETPFQRHTVDYLYRQISAHKEKVVEQQLQLNMHEQTITEFVHDIKTPVTAMKLLIDQEKNQERKQALLYEWSRINSMLDTQLYITRLESQRKDMYFDYVSLKRMVIDEIQLTRHISQVKGIGFDVDFKVDDYVYTDTKWCRMIIRQILSNALKYSENFNIEIGTELNDQHVSLYIKDYGRGISKKDMPRIFERGFTSTANRNETTSSGMGLYLVNSVKDQLGIHLQVTSTVGKGTTVRLIFPLQNEIVERMSEVTNLSF
What is the function of this protein?
Member of the two-component regulatory system GraR/GraS involved in resistance against cationic antimicrobial peptides (CAMPs).  Functions as a sensor protein kinase which phosphorylates GraR through the auxiliary protein GraX.  In turn, GraR up-regulates many genes such as adhesins, exoproteins, transporters, toxins, and proteins involved in cell wall synthesis.  Down-regulates the expression of many genes involved in RNA and amino acid synthesis or glycolysis.
What are the official names of this protein?
Sensor protein kinase GraS, Glycopeptide resistance-associated protein S.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ADAS1_HUMAN
Sequence: MKQLFPPPPGTSLTHALGAWRGRERAQAATSLLASSASQFPTAVEDALMSVLTSHCAPSTPAATRAQQTGTRGHIHPACPCQQSCVGASRPPGRPQIFLPLTTALSLEAYAADTCSAADFLHNPSSWGKVWYLNEASFDLYSYHYFW
What are the official names of this protein?
Putative uncharacterized protein ADARB2-AS1, ADARB2 antisense RNA 1, ADARB2 antisense gene protein 1.
Protein: SSF1_MOUSE
Sequence: MGQSGRSRHQKRNRAQAQLRNLESYAAQPHSFVFTRGRAGRNVRQLSLDVRRVMEPLTATRLQVRKKNSLKDCVAVAGPLGVTHFLILTKTDNSVYLKLMRLPGGPTLTFQISKYTLIRDVVSSLRRHRMHEQQFNHPPLLVLNSFGPQGMHIKLMATMFQNLFPSINVHTVNLNTIKRCLLINYNPDSQELDFRHYSVKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGVGLSDSEVEPDGEHNTTELPQAVAGRGNMQAQQSAVRLTEIGPRMTLQLIKIQEGVGNGNVLFHSFVHKTEEELQAILAAKEEKLRLKAQRQNQQAENLQRKQELREAHKKKSLAGIKRARARADGDSDAEDPGAPPEAVGAGQPEDEEDDAEYFRQAVGEEPDEDLFPTAAKRRRQGGPLGKKQRGKEQRPGNKGRGQGGNWQALKLQGRSQRGKAKPRPRATHQDSRPASRRRN
What is the function of this protein?
May have a role in cell growth.
What are the official names of this protein?
Suppressor of SWI4 1 homolog, Ssf-1, Peter Pan homolog.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ECFA1_LACGA
Sequence: MIFMKDNIVTVEHLSFTYKDSEEPAVKDVSFSIPKGTWTTLVGHNGSGKSTIARLLNGILLPDDNPETLINIDGITLTEKTMWDIRDRVGIVFQNPDNQFVGATVEDDVAFGLENRQVPRPKMKSIVQDVLNQVGMTNFQKSEPQYLSGGQKQRVAIAGILAIGPKLIILDESTSMLDPAGKFKILKLIRKLQKENELTIFSITHDINEAEHADQILVLDKGSLLASDSPVDIFKDVSLIKNAGLDLPLFYKIKNKLINKGISIPQEVNTEEKLVKYLCQLNSKM
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA1, ECF transporter A component EcfA1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PYRR_DEHMC
Sequence: MAQKVILGAEDIRRTLARIAHEILERNQSSRDLVIIGMYTRGVPLANRLAENILRFEGLEIPVGTLDFSLYRDDLDSQRFHPTIKNTDIPFSINNKIVVLVDDVLFTGRSTRAAMDALIDYGRPKAIQLAVLVDRGHRELPVRADYIGKNIPSARDEKIKVRLTETDGQDEVLILDDEAGEV
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: AQP1_CANLF
Sequence: MASEFKKKLFWRAVVAEFLAMILFVFISIGSALGFNYPVRNNQTAGAAQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISILRAVMYIIAQCVGAIVATAILSGITSSLPDNSLGRNELAPGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSGPLAIGLSVALGHLLAIDYTGCGINPARSFGSSVITHNFKDHWIFWVGPFIGGALAVLIYDFILAPRSSDLTDRVKVWTSGQVEEYELDGDDINSRVEMKPK
What is the function of this protein?
Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
What are the official names of this protein?
Aquaporin-1, AQP-1, Aquaporin-CHIP, Water channel protein for red blood cells and kidney proximal tubule.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PLD1_SCHPO
Sequence: MTIHQGGNSVIDNVPYSLNTNVNDSIYSEKGTGRKDAEDHTPSKITDLEKNVDHSIPSFPENDPKNYSEFVNLNPPKRPDLEHTRGSSWHTASENVNDLAANDSTRVQTPEFITQTMEDENVEVPPLERDERDAAAAHTSKANRNSARQMWAQLMASVRKFKREDEKPILKENLPAINLFEAGIPASLPIAKHFIRDKSGQPVLPIITDLIKVSVLDVEPKHNRIHSTFTIQVEYGTGPHAIRWLIYRQLRDFINLHSHFLFFEFQHRFSGRRMKLPKFPKEVLPYLVKLRGYQKILYSNPSDQLIDETHSISDISWESHSQDGDRTTGQPRHANNGRKKHGNFWTIQGNTLGVYLQEMIHNLQFFPEVNVLYSFLEFSSLGLYLAGAGTFHGKEGFATLKRNYSPTQYMLCCNTTMMKTRSQPFWIIVSESCIILCDNMLSMQPADVFIWDVDFEITRKNFRKAHSKDTNEKIRLSHHSFKIKNRQKVMKLSVRSGRWLQQFINSVQVAQGLTAWCEIHRFDSFAPVRTNVAVQWMVDARDHMWNVSRAIKNAKRCIMIHGWWLSPELQMRRPYSMAHKWRIDRILNEKAHEGVMVYIMIYRNIDATIPIDSFHTKEHLQSLHPNIYVIRSPSHFRQNALFWAHHEKLVVVDDAITFIGGIDLCFGRYDTPQHILYDDKPVADKTGLCEQTWRGKDYSNARVHDFFDLTEPYKDMYDRLAVPRMGWHDVSMCIIGQPARDAARHFVQRWNYLIQCKKPARKTPLLIPPPDFTTDQLTDSQLTGTCEVQVLRSAGLWSLGLVDTVEQSIQNAYVTCIEKSEHFIYIENQFFVTSTTCEGTTIENRVGDALVERIIRAHKNNEKWRGVIMIPLLPGFEGQIDLQEGGSLRLIVECQYRSICHGEHSIFGRLNAKGIDGSKYLRFYGLRGWAHLGENHELVTEMIYVHAKILIADDRVAVIGSANINERSLLGNRDSEIAAVIRDTLTIDSKMDGKPYKVGKFAHTLRKRLMREHLGLETDVLEQREYNMDGLDRDTEWKRVEVWTPDEGNAINGSAYTAEELKMKYRSQSQFTTTPDILRKAEKSMKKLDQRVSLIPSSIEFNIKTQKDKVEFEKNYEKSKKGPDVIANALVGGIPLSLKTKEDSLYELSKFSQCGEDQRPMVLKDPDHLVPEPSRPHCGNGLVFYDDIPLLEVNPISGETIPKFDASSFEDPVCDEFFEDIWSKVASNNTTIYRHIFRCVPDDEMLTWESYNEWKKYGKRFKEEQARWRQEELSNLHETHEKSENDPKNPKAGSQGSGNTSASEDSKTEKPKTRTNNGLQVPDKRVVYDLLRGIRGQLVELPLKWMSTESNARNWLSSIDKIPPLEIYD
What is the function of this protein?
Required for meiosis and spore formation.  Seems to be involved in the coordinate induction of late meiotic events.
What are the official names of this protein?
Phospholipase D1, PLD 1, Choline phosphatase 1, Phosphatidylcholine-hydrolyzing phospholipase D1.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRAM5_ORYSJ
Sequence: MEIERESSERGSISWRASAAHDQDAKKLDADDQLLMKEPAWKRFLAHVGPGFMVSLAYLDPGNLETDLQAGANHRYELLWVILIGLIFALIIQSLAANLGVVTGRHLAEICKSEYPKFVKIFLWLLAELAVIAADIPEVIGTAFAFNILFHIPVWVGVLITGTSTLLLLGLQKYGVRKLEFLISMLVFVMAACFFGELSIVKPPAKEVMKGLFIPRLNGDGATADAIALLGALVMPHNLFLHSALVLSRKTPASVRGIKDGCRFFLYESGFALFVALLINIAVVSVSGTACSSANLSQEDADKCANLSLDTSSFLLKNVLGKSSAIVYGVALLASGQSSTITGTYAGQYIMQGFLDIRMRKWLRNLMTRTIAIAPSLIVSIIGGSRGAGRLIIIASMILSFELPFALIPLLKFSSSKSKMGPHKNSIYIIVFSWFLGLLIIGINMYFLSTSFVGWLIHNDLPKYANVLVGAAVFPFMLVYIVAVVYLTIRKDSVVTFVADSSLAAVVDAEKADAGDLAVDDDEPLPYRDDLADIPLPR
What is the function of this protein?
Probable metal transporter.
What are the official names of this protein?
Metal transporter Nramp5.
What is the protein family that this protein belongs to?
Belongs to the NRAMP (TC 2.A.55) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NUOC_NEOSM
Sequence: MTIDTTEVDALINAPGRCVVNSSLESLVELISHLSSCGFEQLTDIFGIDYLEREKRIEVVYLLLDLKRNRRCCVKVSVDPASEKVPTCCGVFSVANWFEREVYDMYGVVFEGHPDLRRILTDYEFEGFPMLKDFPLTGYKEVRYDLESKEVVYEKVDLSQDYRSFDSLTPWKGVGRPSDPFDGRKE
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SUHB_XYLFT
Sequence: MQKPAVNIMVKAARSAGNVLLRHINKLETLHVIQKSRMDYASDVDEMAEKVIVKELKRAYPDYGILGEEGGLQGNHRIMWVIDPLDGTSNYLRGFPHYCVSIALVENGEPTDAVIFDPLRNELFTASRGAGAVLNERKIRVANRKDLNGTMLNTGFSPRERSRAHAQLKCVDALLMQAEDIRRSGSAALDLAYVACGRADAYFEAGIKVWDVAAGMLLVREAGGYVCDFKGADAPRMDDKGPESCQLIAGNIKVAHALQQVIVSSGYGREFDPKR
What is the function of this protein?
Part of the processive rRNA transcription and antitermination complex (rrnTAC).  The complex forms an RNA-chaperone ring around the RNA exit tunnel of RNA polymerase (RNAP).  It supports rapid transcription and antitermination of rRNA operons, cotranscriptional rRNA folding, and annealing of distal rRNA regions to allow correct ribosome biogenesis.  This subunit may play a central role in organizing the structure.
What are the official names of this protein?
Nus factor SuhB, Inositol-1-monophosphatase, I-1-Pase, IMPase, Inositol-1-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GALE_STRMU
Sequence: MAILVLGGAGYIGSHMVDRLIEKGEEEVVVVDSLVTGHRAAVHPAAKFYQGDLADREFMSMVFRENPDVDAVIHFAAYSLVAESMKKPLKYFDNNTAGMIKLLEVMSEFGVKYIVFSSTAATYGIPDEIPIKETTPQRPINPYGESKLMMETIMKWSDRAYGIKFVPLRYFNVAGAKPDGSIGEDHSPETHLLPIILQVAQGVREKIMIFGDDYNTPDGTNVRDYVHPFDLADAHLLALNYLRQGNPSTAFNLGSSTGFSNLQILEAARKVTGQKIPAEKAARRSGDPDTLIASSEKAREVLGWKPQFDDIEKIIASAWAWHSSYPKGYDDRD
What is the function of this protein?
Involved in the metabolism of galactose.  Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity).
What are the official names of this protein?
UDP-glucose 4-epimerase, Galactowaldenase, UDP-galactose 4-epimerase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Protein: MT2_CYPCA
Sequence: MDPCDCAKTGTCNCGATCKCTNCQCTTCKKSCCSCCPSGCSKCASGCVCKGNSCGSSCCQ
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein-2, MT-2, Metallothionein-II, MT-II.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: GAD_THETE
Sequence: MASAMASSALREATCTMTRLAADVAASVSSIFSCKDSAGPRPVVPATKTTSTPLDVMFFTWFAKSSGSSLPPLKVVMTGATISIDSTRGALKKLARKGIKGWLNQYMATIKEIEPIVLYEQETDARWASYSILVRVVTSDGRVSYGEAVPTLRILPVVSAVRQTARAFLGRDPHEISAAFYEWYRQDFFLSRSFESATALSAIDMALWDLKARELGAPLYELLGGKLRDRVKVYANGWYGGCRDPQCFAEKAKEVVARGYDALKFDPFGPSFNSITSEELRRAEEAVAAVRDAVGDDVDILIEHHGRFNANAAVEIAKRFEPYRPYFMEEPLHHEDIEGYRKYRSLTSARIAMGERLISAKEALQYLVEGLVDVIQPDACNIGGVTGSMKVAALAEAFSVEVSYHNAYGPVQFALEVQLSAVTPTLYRLESFYDYWPQWKRDLIGDPFRLSQSSVEVPRGPGIGVAVNERVLEKYRAEPSEIPVGEEPVWVVRGTWR
What is the function of this protein?
Involved in the degradation of glucose via the Entner-Doudoroff pathway.  Catalyzes the dehydration of gluconate to produce 2-keto-3-deoxygluconate (KDG).  It is not able to use D-galactonate as substrate.
What are the official names of this protein?
D-gluconate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GaD subfamily.
Protein: IFNAG_BOVIN
Sequence: MAPAWSLLLALLLLSCNAICSLGCHLPHTHSLANRRVLTLLRQLRRVSPSSCLQDRNDFAFPQEALGGSQLQKAQAISVLHEVTQHTFQFFSVEGSAVVWDESLLDKLRDALDQQLTDLQFCLRQEEGLRGAPLLKEDSSLAVRKYFHRLTLYLQEKRHSPCAWEVVRAEVMRAFSSSTNLQERFRRKD
What is the function of this protein?
Produced by macrophages, IFN-alpha have antiviral activities.  Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
What are the official names of this protein?
Interferon alpha-G, IFN-alpha7.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS13_ALIF1
Sequence: MARIAGINIPDHKHAVIALTAIYGIGKTRSQAILAEVGIAEDVKISELNDEQIDILRDGVAKYTVEGDLRREVSMNIKRLMDLGCYRGLRHRRSLPLRGQRTKTNARTRKGPRKPIKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: MIAA_ALKOO
Sequence: MKKRLLIIVGPTAVGKTDTSIILAKELNGEIISADSMQIYRYMDIGTAKPNEEEKKGIPHHLIDIVNPDEEFSVAEFQKIAKNHINRLIEDEKLPIVAGGTGLYINSLIYDMDFTQSISNWELRGALEAEAREKGNEYVYNKLKQIDPHAAARIHPNNLKKVIRAIEVYEETGEKIGDFSTDLNINQEYDVFFVGLTRDREELYDRINMRVDAMIEQGLIEEVKNLLSLGYDKNLIAFKGLGYKEIIGYLEGAYSLEEAMDILKRDTRRYAKRQLTWFRRYENIHWYNLSNYDSCENLAECILKDFKGHFNSL
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: AC4_CALCV
Sequence: MKLFRCFKPCRGQSSNPHTSESQERNIQTGSPIYTVSSNYQESRTSRMLDFSTSLTPEGLPIFTQTFRQPKTPMPSRITSPKMVIIVNPGSTRCLGVQRQIKTTSTTTPSMRDVWKRLSQL
What is the function of this protein?
Pathogenicity determinant (By similarity).  May act as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.
What are the official names of this protein?
Protein AC4, Protein AL4.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae protein AC4/C4 family.
Protein: DXR_CHLPB
Sequence: MKSLSILGSTGSIGLSTLDVVRQHPEKFNVTGLAEGHDINLLAEQIKEFRPDIVSVRDKASAGLLREQLGSEKPEILWGIEGAAAVGAAEGSEMVVSAIVGAAGLVPTVSAIKAGKDIALANKETLVVAGQLVSDLVKEHKVTLLPVDSEHSAIFQSLSGHRKEDIERIILTASGGPFRHTSAEDLRHVGPEKALKHPQWTMGAKITIDSATLMNKGLEVIEAHWLFDMPADKIGVVVHPQSIIHSMVEYIDGCVMAQLGAPDMRAPIAYALAWPERCESGIKKLDLTQIGTLTFEQPDMERFPALRLAFDALKAGQTFPAVLNAANEIAVAAFLDKKIGFTDIPAIADRTMQAHDPYTPSGLDEYLAADRWARDTAKTMTN
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: CATQ_RAT
Sequence: MTPAVFLVILCLGVVPGASALDLSLDVQWQEWKIKYEKLYSPEEEVLKRVVWEENVKKIELHNRENSLGKNTYTMEINDFADMTDEEFKDMIIGFQLPVHNTEKRLWKRALGSFFPNSWNWRDALPKFVDWRNEGYVTRVRKQGGCSSCWAFPVTGAIEGQMFKKTGKLIPLSVQNLIDCSKPQGNRGCLWGNTYNAFQYVLHNGGLEAEATYPYERKEGVCRYNPKNSSAKITGFVVLPESEDVLMDAVATKGPIATGVHVISSSFRFYQKGVYHEPKCSSYVNHAVLVVGYGFEGNETDGNNYWLIKNSWGKRWGLRGYMKIAKDRNNHCAIASLAQYPTV
What are the official names of this protein?
Cathepsin Q.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: LPOA_HAEIN
Sequence: MSILLQGERFKKRLMPILLSMALAGCSNLLGSNFTQTLQKDANASSEFYINKLGQTQELEDQQTYKLLAARVLIRENKVEQSAALLRELGELNDAQKLDRALIEARISAAKNANEVAQNQLRALDLNKLSPSQKSRYYETLAIVAENRKDMIEAVKARIEMDKNLTDVQRHQDNIDKTWALLRSANTGVINNASDEGNAALGGWLTLIKAYNDYIRQPVQLSQALQSWKNAYPNHAAATLFPKELLTLLNFQQTNVSQIGLLLPLSGDGQILGTTIQSGFNDAKGNSTIPVQVFDTSMNSVQDIIAQAKQAGIKTLVGPLLKQNLDVILADPAQIQGMDVLALNATPNSRAIPQLCYYGLSPEDEAESAANKMWNDGVRNPLVAMPQNDLGQRVGNAFNVRWQQLAGTDANIRYYNLPADVTYFVQENNSNTTALYAVASPTELAEMKGYLTNIVPNLAIYASSRASASATNTNTDFIAQMNGVQFSDIPFFKDTNSPQYQKLAKSTGGEYQLMRLYAMGADAWLLINQFNELRQVPGYRLSGLTGILSADTNCNVERDMTWYQYQDGAIVPVAN
What is the function of this protein?
Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).
What are the official names of this protein?
Penicillin-binding protein activator LpoA, PBP activator LpoA.
What is the protein family that this protein belongs to?
Belongs to the LpoA family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side.