PharMolix/UniProtQA huggingface dataset:
Protein: RNH2_MYCBO
Sequence: MTKTWPPRTVIRKSGGLRGMRTLESALHRGGLGPVAGVDEVGRGACAGPLVVAACVLGPGRIASLAALDDSKKLSEQAREKLFPLICRYAVAYHVVFIPSAEVDRHGVHVANIEGMRRAVAGLAVRPGYVLSDGFRVPGLPMPSLPVIGGDAAAACIAAASVLAKVSRDRVMVALDADHPGYGFAEHKGYSTPAHSRALARLGPCPQHRYSFINVRRVASGSNTAEVADGQPDPRDGTAQTGEGRWSKSSHPATMRATGRAQGT
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM218_BOVIN
Sequence: MAGTVLGVGAGVFVLALLWVSVLLLCALLFRASGAARFSVIFVFLGALIVTAILLLFPRASDAPAPEAETKIVDAFFIGRYVLLAFLTAVFLGSLFLVLIHHILEPIYAKPLRSY
What is the function of this protein?
May be involved in ciliary biogenesis or function.
What are the official names of this protein?
Transmembrane protein 218.
What is the protein family that this protein belongs to?
Belongs to the TMEM218 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell projection, cilium. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme.
Protein: GP2_SOLLC
Sequence: MHNKILVSSYILLVLLFSLSSFNIVVAKDGDESGNPFTPKGYVIRYWNKHVSNDLPKPWFLLNKASPLNAAQYATYTKLVADQNALSTHLQSFCSSANLMCAPDLLPSLEKHTGDIHFTTYGNKNFTNYGTNEPGIGVNTFKNYSEDASVNSFRRYGRGSPRDNKFDNYAPDGNVIDQSFNSYSTNTPGGSGQFTNYAPNTNVPDLRFTAYSDQGTGGEQEFKTYLEQGNSGGQSFKSYGKNGNGADSKFTSYGNETNVAASTFKNYGQNANGENQNFTSYSTNGNNPQNNFKNYGVGGNGPSETFTNYRDESNVGDDKFSNYVKDANAGEANFTNYGQSFNEGTDVFITYGKGGNDPHINFKTYGVNNTFKDYVKDTATFSNYHNKTSQDLASLSEVNGGKKVNNRWIEPGKFFREKMLKSGTIMPMPDIKDKMPKRSFLPRAIAAKLPFSTSKIDELKKIFHAANDSQVAKMIGDALSECERAPSPGETKQCVNSAEDMIDFATSVLGRNVVVRTTENTNGSKGNIMIGSIKGINGGKVTKSVSCHQTLYPSLLYYCHSVPKVRVYEADILDPNSKAKINHGVAICHVDTSSWGPRHGAFIALGSGPGKIEVCHWIFENDMTWATAD
What is the function of this protein?
Non-catalytic subunit of polygalacturonase.
What are the official names of this protein?
Polygalacturonase non-catalytic subunit AroGP2.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast. Secreted, cell wall. Note=Associated to the cell wall.
Protein: RECF_MYCS2
Sequence: MFARHLGLTDFRSWARVDLDLEPGRTVFVGPNGFGKTNLVEALWYSATLGSHRVATDAPLIRAGAERAIVSTIVVNEGRELAVDLEITSGRANKARLNRSPVRSAREILGVLRAVLFSPEDLSLVRGDPGDRRRYLDELATTRRPALAGVRADYDKVVRQRTALLKTAAGARYRGDRSVIDTLEVWDGHLAAHGAALVASRVKLVEELQPEVEKAYQLLAPASRPAAIRYRSSVEAIEDAPGPESVEFYEAALLDALARRRDAELERGVCLVGPHRDDLELRLGDQPAKGFASHGESWSMALALRLGAYELLCSDGVEPVLLLDDVFAELDTSRRRALATVAGSAEQVLVTAAVGEDIPEDWDARRVEIRMVEDDGGRVSMVAS
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP (By similarity).
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_CAMJR
Sequence: MSVKNIRNFSIIAHIDHGKSTLADRIISECGAISDRQMSSQVMDTMDIEKERGITIKAQSVRLNYKFNNENFVLNLIDTPGHVDFSYEVSRSLASCEGALLVVDASQGVEAQTIANVYIALENNLEIIPVINKIDLPNADVEKVKHEIEHIIGIDCKDAICVSAKTGVGIKELIETIITKIPAPKTDDEAPTKALIYDSWFDNYLGALALVRIYEGSIAKNDEVLVMSTDKKHIVQDLFYPHPLSPIKTQSLQSGEVGVVVLGLKTVGDVQVGDTITLVKNKAKEAIGGFEKAKAFVFAGLYPIETDKFEDLRDALDKLKLNDSSITYEPETSLALGFGFRVGFLGLLHMEVIKERLEREFNLDLIATAPTVTYEIYQTDGEFIKIQNPSELPPVNKIDHIKEPYVKATIITPSEFLGNLITLLNRKRGVQVKMDYITPERVLLEYDVPLNEIVMDFYDKLKSLTKGYASFDYEPIEFRVGDLVKLDIKVAGENVDALSIIVPNEKAQSKGRELVSAMKEIVPRQLFEVAIQASIGNKIIARETVKSMGKNVTAKCYGGDITRKRKLLEKQKEGKKRMKAIGKVNLPQEAFLSVLKID
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PDXJ_WOLWR
Sequence: MKLGVNIDHVATLRNARGTSYPDPLKAAEIAIDAGADFITVHLREDRRHIRDEDVFNLKKSISTELNLEIAATEEMLEIAKKVKPYSISIVPEKREELTTEGGLDIVNMHSKLSSIIEEMHSSSIKVSLFIDPNIDQLKYLEKLGTKPDIIEIHTGDYCDNPSEKKLQLITNAAEYVNKLGIECHAGHGITYEHAKKMTRIPHISALNIGHYLISEAVFYGLHSVVKTMKMTMSN
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_CLOB6
Sequence: MLEIEKPKIECVENAEDGSYGKFVIEPLERGYGITLGNALRRILLSSLPGVAADHIKIDSVLHEFSTVQGVKEDVTELILNIKCLALTMNGEGPKTIYIDEVGPKEVTAADIKTDGDVEVINKDLHIATLDENGKMYMEINVNRGRGYVTQNKNKTKDMPIGSIAVDSIYTPVKRVNFSVENTRVGQITDYDKLTIEVWTNGTIRPEEAVSLSAKILIEHFKLFMTLTDHADDMEIMVEKEEDKKEKVLEMTIEELDLSVRSYNCLKRAGINTVQELCERSMDDMMKVRNLGKKSLEEVEQKLEALGLGLRKSED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: NOSO_STAAC
Sequence: MLFKEAQAFIENMYKECHYETQIINKRLHDIELEIKETGTYTHTEEELIYGAKMAWRNSNRCIGRLFWDSLNVIDARDVTDEASFLSSITYHITQATNEGKLKPYITIYAPKDGPKIFNNQLIRYAGYDNCGDPAEKEVTRLANHLGWKGKGTNFDVLPLIYQLPNESVKFYEYPTSLIKEVPIEHNHYPKLRKLNLKWYAVPIISNMDLKIGGIVYPTAPFNGWYMVTEIGVRNFIDDYRYNLLEKVADAFEFDTLKNNSFNKDRALVELNYAVYHSFKKEGVSIVDHLTAAKQFELFERNEAQQGRQVTGKWSWLAPPLSPTLTSNYHHGYDNTVKDPNFFYKKKESNANQCPFHH
What is the function of this protein?
Catalyzes the production of nitric oxide.
What are the official names of this protein?
Nitric oxide synthase oxygenase, NOSoxy-like protein, SANOS.
What is the protein family that this protein belongs to?
Belongs to the NOS family. Bacterial NOS oxygenase subfamily.
Protein: RL17_RICB8
Sequence: MRHKIKGRKLNVTSSHRKAMLANMAVSLVTHEQIKTTLPKAKELRPYIEVLVTKAKDNNLAARRNILSKIKDKKAIEKLIDVLGVRYKDRPGGYTRIVKAGFRYGDLAPIAYIEFVDRDINAKGNIPQDNSKEDIKSNKGTK
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RL10_BACC1
Sequence: MSKVIETKQQVVTEIADKLRASKSTIVVDYRGLTVSEATELRKQLREAGVEFKVYKNSLTRRAAESAEMAELNEFLTGPNAIAFSNEDVVAPAKVLNDFAKDHEALEIKAGVIEGKLVTLDEVKAIATLPSREGLLSMLLSVLQAPIRNLALATKAVADQKEEQGA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: LOLA_COXBU
Sequence: MNTIKILIGLLGIFLFSLSGIVSAQSDATTQLSQLLSNFRTYQAKFNQITFDGQDRVIQQSHGRVMIMRPGRFRWETDSPTKQIIITNGKTLWVYDVDLSQATQQPLAQKTNINPASLLSGSVKDLKQKFTITISPTPDAATFQLVPNLGKSLNFNWIRLKFSKKQLTEMTVLNNLDERSIFQFSQIKVNAPLSSTLFEFKPSRGIDVVKQ
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RDRP_ROTPY
Sequence: MGKYNLILSEYLSFVYNSQSAVQIPIYYSSNSELEKRCIDFHAKCVDNSKKGLSLSSLFEEYKDVIDNATLLSILSYSYDKYNAVERKLINYAKGKPLEADLTANELDYENNKITSELFKSAEEYTDSLMDPAILTSISSNLNAVMFWLERHSNDVGDANKVYRRRLDLFIIVASTINKYGVPRHNEKYRYEYEVMKDKPYYLVTWANSAIEMLMSVFSHEDYLIAKELIILSYSNRSTLAKLVSSPMSILVALIDINGTFITNEELELEFSDKYVKAIVPDQTFNELQEMIDNMKKAGLVDIPRMIQEWLVDCSLEKFTLMSKIYSWSFHVGFRKQKMIDAALDQLKTEYTEDVDNEMYNEYTMLIRDEIVKMLEVPVKHDDHLLRDSELAGLLSMSSASNGESRQLKFGRKTIFSTKKNMHVMDDIAHGRYTPGVIPPVNVDRPIPLGRRDVPGRRTRIIFILPYEYNSAQHAVVEKMLSYAKHTREYAEFYSQSNQLLSYGDVTRFLSSNSMVLYTDVSQWDSSQHNTQPFRKGIIMGLDMLANMTNDPKVVQTLNLYKQTQINLMDSYVQIPDGNVIKKIQYGAVASGEKQTKAANSIANLALIKTVLSRIANKYSFITKIIRVDGDDNYAVLQFNTDVTKQMVQEVSNDVRYIYSRMNAKVKALVSTVGIEIAKRYIAGGKIFFRAGINLLNNEKRGQSTQWDQAAILYSNYIVNKLRGFDTDREFILTKIIQMTSVAITGSLRLFPSERVLTTNSTFKVFDSEDFIIEYGTTDDEVYIQRAFMSLSSQKSGIADEIASSQTFKNYVSKLSDQLLVSKNAIVSKGIAVTEKAKLNSYAPVYLEKRRAQISALLTMLQKPVSFKSNKITINDILRDIKPFFVTTEAKLPIQYRKFMPTLPDNVQYVIQCIGSRTYQIEDSGSKSSISKLISKYSVYKPSIEELYKVISLREQEIQLYLVSLGVPPVDAGTYVGSRIYSQDKYKILESYVYNLLSINYGCYQLFDFNSPDLEKLIRIPFKGKIPAVTFILHLYAKLEIINYAIKNKSWISLFCNYPKSEMIKLWKKMWNITALRSPYTSANFFQD
What is the function of this protein?
RNA-directed RNA polymerase that is involved in both transcription and genome replication.  Together with VP3 capping enzyme, forms an enzyme complex positioned near the channels situated at each of the five-fold vertices of the core.  Following infection, the outermost layer of the virus is lost, leaving a double-layered particle (DLP) made up of the core and VP6 shell.  VP1 then catalyzes the transcription of fully conservative plus-strand genomic RNAs that are extruded through the DLP's channels into the cytoplasm where they function as mRNAs for translation of viral proteins.  One copy of each of the viral (+)RNAs is also recruited during core assembly, together with newly synthesized polymerase complexes and VP2.  The polymerase of these novo-formed particles catalyzes the synthesis of complementary minus-strands leading to dsRNA formation.  To do so, the polymerase specifically recognizes and binds 4 bases 5'-UGUG-3' in the conserved 3'-sequence of plus-strand RNA templates.  VP2 presumably activates the autoinhibited VP1-RNA complex to coordinate packaging and genome replication.  Once dsRNA synthesis is complete, the polymerase switches to the transcriptional mode, thus providing secondary transcription (By similarity).
What are the official names of this protein?
RNA-directed RNA polymerase, Protein VP1.
What is the protein family that this protein belongs to?
Belongs to the reoviridae RNA-directed RNA polymerase family.
What are the subcellular locations of this protein?
Virion. Note=Attached inside the inner capsid as a minor component. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging (By similarity).
Protein: ILVC_VIBPA
Sequence: MANYFNTLNLREQLDQLGRCRFMDREEFVSEADYLKGKKVVIVGCGAQGLNQGLNMRDSGLDVSYALRQAAIDEQRQSFKNAKDNGFEVGSYETLIPQADLVVNLTPDKQHTNVVETVMPLMKEGAALGYSHGFNVVEEGMQIRKDLTVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGWDIAKAWAAATGGHRAGCLESSFVAEVKSDLMGEQTILCGMLQAGSIVCYEKMIAEGIDPGYAGKLLQYGWETITEALKFGGITHMMDRLSNPAKIKAFELSEELKDLMRPLYNKHMDDIISGHFSSTMMADWANDDKNLLGWRAETGETAFENYPETDVEISEQEYFDNGILMVAMVRAGVELAFEAMTASGIIDESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFANVATPLLREKFMPSVGTDVIGKGLGETSNQVDNATLIAVNETIRNHPVEYIGEELRGYMTDMKRIAVGG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: PURO_METM5
Sequence: MYIGRFLVFGKTEEGYPFVTYRVSSRSFPNRLAKVMDDDTVSILPKELEEMFKNPYITYNCVKLVGDVAVATNGSHTDIIADKIKLGLPIRDALSYSLLTMDYEKDDYNTPRIAVVITKDEAYMGYVTDSDVRIKKVELEAGKAYYLGVYDACKITEHQVISVTGKTAEDLTKFVMDYEEFEKPVTAATVLVKDGFKLATL
What is the function of this protein?
Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.
What are the official names of this protein?
IMP cyclohydrolase, IMP synthase, Inosinicase.
What is the protein family that this protein belongs to?
Belongs to the archaeal IMP cyclohydrolase family.
Protein: CNDP2_HUMAN
Sequence: MAALTTLFKYIDENQDRYIKKLAKWVAIQSVSAWPEKRGEIRRMMEVAAADVKQLGGSVELVDIGKQKLPDGSEIPLPPILLGRLGSDPQKKTVCIYGHLDVQPAALEDGWDSEPFTLVERDGKLYGRGSTDDKGPVAGWINALEAYQKTGQEIPVNVRFCLEGMEESGSEGLDELIFARKDTFFKDVDYVCISDNYWLGKKKPCITYGLRGICYFFIEVECSNKDLHSGVYGGSVHEAMTDLILLMGSLVDKRGNILIPGINEAVAAVTEEEHKLYDDIDFDIEEFAKDVGAQILLHSHKKDILMHRWRYPSLSLHGIEGAFSGSGAKTVIPRKVVGKFSIRLVPNMTPEVVGEQVTSYLTKKFAELRSPNEFKVYMGHGGKPWVSDFSHPHYLAGRRAMKTVFGVEPDLTREGGSIPVTLTFQEATGKNVMLLPVGSADDGAHSQNEKLNRYNYIEGTKMLAAYLYEVSQLKD
What is the function of this protein?
Catalyzes the peptide bond hydrolysis in dipeptides, displaying a non-redundant activity toward threonyl dipeptides (By similarity).  Mediates threonyl dipeptide catabolism in a tissue-specific way (By similarity).  Has high dipeptidase activity toward cysteinylglycine, an intermediate metabolite in glutathione metabolism (PubMed:19346245, PubMed:12473676).  Metabolizes N-lactoyl-amino acids, both through hydrolysis to form lactic acid and amino acids, as well as through their formation by reverse proteolysis (PubMed:25964343).  Plays a role in the regulation of cell cycle arrest and apoptosis (PubMed:17121880, PubMed:24395568).
What are the official names of this protein?
Cytosolic non-specific dipeptidase, CNDP dipeptidase 2, Glutamate carboxypeptidase-like protein 1, Peptidase A, Threonyl dipeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VRAB_STAES
Sequence: MKQPVIIAAKRIAFGKYGGRLRHLEPESLLEPLFNHFTDQYPKVMSLLDDVILGNTVGNGGNLARKSLLEAGLDFKIPGITIDRQCGSGLEAVIQACRMVQSGAGTIYIAGGVESTSRAPWKIKRPQSVYESEFPQFFERAPFAREGEDPSMIEAAENVAKKYHISRNEQDDFAYRSHQLASKNMNNGNISQEILPFKVKGEYFNQDESIKPQLTLRTLGRLKPLLNEGTVTVGNSCKKNDGAVLLIVMEENRARQLGFTEGIKFVNSATVGVQPQYLGVGPVPAVNQLLAQERLTINDINAVELNEAFSSQVIASQQQLNIPLNKLNCWGGAIATGHPYGASGAALVTRLFYMKHQFRTIATMGIGGGIGNAALFERWYGN
What are the official names of this protein?
Putative acetyl-CoA C-acetyltransferase VraB.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
Protein: PRT2_SEPOF
Sequence: MKVAANTSKMLVEKLDLLKGGRRRRRRSRRRRRSRRRRSRSPYRRRYRRRRRRRRSRRRRRYRRRRSYSRRRYRRRR
What is the function of this protein?
Cuttlefish spermiogenesis is characterized by a double nuclear protein transition: histones -> spermatid-specific proteins (T1/T2) -> protamines (SP1/SP2).  The protamines compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Spermatid-specific protein T2.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: DNAE2_NOCFA
Sequence: MGWGTGPPSWSELERVLSGRPGRTDPEAMYPGDGGDSPAWSRKREPYLAEPIRPVDRPTVPYAELHAHSAYSFLDGASQPEELVEEAVRLGLEAIALTDHDGFYGTVRFAEAAKEWGIATVFGAELSLGVARPAPRRSARKAARGRGRAVRYAATPEFEHAAAPDSAPRTGEPDPPGPHLLVLARGQEGYRRLSREIAAAHLAAGEKGVLRYDIDALTAAAGGHWHILTGCRKGHLRTALADDLAAGETGLPRAEAALRDLVERFGADRVSVELTHHGVPADDERNALLIALADRVGLPVLATTGAHFAGPEQRRRAMALAAIRARRSLDEMAGWLAPAGGAHLRSGAEMARLFAACPDAVANAVALSRECAFDLRLIAPQLPPFAVPDGHDENSWLRELVLRGAARRYGPPHANPPAYRQLEHELEVIATLGFPGYFLVVHDIVSFCERNGILCQGRGSAANSAVCFAIGITNVDPVANELLFERFLSPERDGPPDIDIDIESDRREEAIQHVYARYGREYAAQVANVITYRGKSAVRDAAKALGFSPGQQDAWSKQVSRWTGVGAETGTDIPEQVLRLAADLEGLPRHMGIHSGGMVICDRPIADVCPVEWARMAGRSVLQWDKDDCAAVGLVKFDMLGLGMLSALHYMIDLVREHEGVEVRLHELDLKEPAVYEMLSRADSVGVFQVESRAQMATLPRLRPREFYDLVVEVALIRPGPIQGGSVHPYIRRRNGTEPVTYDHPALENSLGRTLGVPLFQEQLMQMAVDVAGFTAAEADQLRRAMGSKRSPERMRRLKERLYRGMAELHGITGEVADRIYEKLYAFANFGFPESHSQSFAALVFYSAWFKLHHPAAFCAGLLRAQPMGFYSPQSLVADARRHGVPVHGPDVNASLAEATLENGGREVRLGLAGVRHIGSELAERIVAARVEHGPYTSVLDLTGRVELTVAQAEALATAGAFDSVTGPSGAERSGGRRAALWAAGAAARERAHLLPGTGPAADAPALPGMSALELAAADVWATGISPGSYPTEFLRARMDELGVIPAGRLLEVRDGSRVLVGGAVTHRQRPATAAGVTFLNLEDETGMVNVVCSVGLWTRYRALAQSASALLVRGRVQNAEGAVSVVAEHLQLLSLGMGSRSRDFR
What is the function of this protein?
DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS).  It is not the major replicative DNA polymerase.
What are the official names of this protein?
Error-prone DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GKP1B_XENLA
Sequence: MASAVVSMVSTTASRFALLKVDSSSDSDSEKARGTHTSGKAHSGSAARGKTNVNEKKKEKRRKKKEQQQSEANELRNLAFKKIPPKASLGVSAAVQEHITHTVPKDAQKEDWQQWQQRDKQLTSDMFEADLEKALILSKLEYEESKVNGDGVNGVPQSKKVNKKDKRKNNQGKDKPLTVPLKDFQLEDQQAKKQEELKSPALPQGSGFFNKVEDDVTKIILNEKRKEHSTDVTESFATPEYSTEPALKDGKTEVLKQEIEKKEIALQQMRSKISQWEAKYREVKARNSQLLKMLQEGEMKDKAEILLQVDELLSIKNELTLQVTTLHAALEQERSKVKVLQAEQVRYQGGKKSKRNPELEHGR
What is the function of this protein?
May play a role in the regulation of insulin-dependent IRS1 tyrosine phosphorylation in adipocytes.
What are the official names of this protein?
G kinase-anchoring protein 1-B.
What is the protein family that this protein belongs to?
Belongs to the GKAP1 family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: ATG33_LACTC
Sequence: MSVCLAVTKTVAVSSLGIYCGMLTSACVASYAAPVDVLTQLAKPARVIARVGGALAAVSSAFFALSYFGAPAHWRHPYLLYGMLVAPVSAAYVAVVARVRGAHCRRACEKRRAQSASVHASTPASAAPEPALDDSVVDLGAAAAAAESAPETHVTSAEHVPVSHHVTPASAACARAAARHAAVLLLPAAAGLLGSVLGLYGEGLFV
What is the function of this protein?
Involved in the selective degradation of mitochondria via autophagy during starvation and at post-log phase.
What are the official names of this protein?
Autophagy-related protein 33.
What is the protein family that this protein belongs to?
Belongs to the ATG33 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: RL28_SYNR3
Sequence: MSRVCQLSGKRANNGMAVSHSHVRTKKLQQVNLQQRRLWWAEGNRWVKLRVSTSALRTIQKKGLGAYAKELGINLAKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: FABH_POLNS
Sequence: MSIFARVAGTGSYLPELRLTNQDLVERLAKTGLETSDEWIKTRSGISARHFAAENELTSDLAVRAAEAALSSTGINSADLDLIILATSTPDHLGGFPSTACVVQDKLGAHTSCAAFDVQAVCAGFTYALAVADAFIRSGSYKKVLVIGAETFSRILNFQDRGTCVLFGDGAGAVVLEASKEAGILSTVMHADGSQRDILCVPGRAGNGEVRGSPFMTMDGQAVFKLAVKVLEQVAHEALDKAKLKPEQIDWLVPHQANIRIMEGTAKKMGMSMDKVIVTVHEHGNTSAASIPLALDSGVRSGQIKRGQHLLLEGVGGGFAWGAVAIKY
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAC_KLEP7
Sequence: MNNNLPSEAVAHAVAVLKNEHVIAYPTEAVFGVGCDPDSETAVMRLLELKQRPVEKGLILIAASFEQLKPYIDDSRLSDSQREAIFSCWPGPVTFVFPARPETPRWLTGRFDSLAVRVTNHPLVIELCEAYGKPLVSTSANLTGQPPCRTTAEVHAQFGDSFPVVDGATGGRQNPSEIRDALTGELFRQG
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PME2_CITSI
Sequence: MALRILITVSLVLFSLSHTSFGYSPEEVKSWCGKTPNPQPCEYFLTQKTDVTSIKQDTDFYKISLQLALERATTAQSRTYTLGSKCRNEREKAAWEDCRELYELTVLKLNQTSNSSPGCTKVDKQTWLSTALTNLETCRASLEDLGVPEYVLPLLSNNVTKLISNTLSLNKVPYNEPSYKDGFPTWVKPGDRKLLQTTPRANIVVAQDGSGNVKTIQEAVAAASRAGGSRYVIYIKAGTYNENIEVKLKNIMFVGDGIGKTIITGSKSVGGGATTFKSATVAVVGDNFIARDITIRNTAGPNNHQAVALRSGSDLSVFYRCSFEGYQDTLYVHSQRQFYRECDIYGTVDFIFGNAAVVLQNCNIFARKPPNRTNTLTAQGRTDPNQSTGIIIHNCRVTAASDLKPVQSSVKTFLGRPWKQYSRTVYIKTFLDSLINPAGWMEWSGDFALNTLYYAEYMNTGPGSSTANRVKWRGYHVLTSPSQVSQFTVGNFIAGNSWLPATNVPFTSGL
What is the function of this protein?
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
What are the official names of this protein?
Pectinesterase 2, PE 2, Pectin methylesterase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the pectinesterase family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: PSD_FRAT1
Sequence: MRDNLFIYLQYLLPHTLTSRLVSKLADSENKIIKNHLIKLAIKKFNINLVEAKETDISKYKSFNDFFIRELKDDLRPISNDKNVISSPADGVLSQFGTITDNSLIQAKGKLFSLESLIASSSTTSFTKFATIYLSPKDYHRVHMPIDGKLTKMVYIPGKLFSVNKITTSKVDNLFAKNERLICYFDTIIGEIAVIFVGALLVAGIETVWHGKIAPNYYKDIQTWDYNSAKFNIKFNKGDILGWFNFGSTVIILTSGNNVSFKFEENKNNIKIQVNQDLALITE
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TRMD_ARTS2
Sequence: MRIDVVSIFPEYLAPLELSLIGKARQDGILDLNVHDLREFTTDKHRSVDDTPYGGGAGMVMKAEPWAQALSTVAAARAGDAARKPVLIVPSPAGERFTQALAHELAGEEQLVFACGRYEGIDERVIEWAEEHFTVRPMSLGDYVLNGGEVAVLAMTEAIVRLLPGVVGNPESLVEESHSDGLLEYPVYTKPSSWRDREVPPVLLSGNHGKIAQWRRHQQYRRTAQRRPDLLAEFDAGNLPRADRTALGDLGYDVVDGHLRHRPEEPGNGAPADG
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.