PharMolix/UniProtQA huggingface dataset:
Protein: PFKA_ACTP2
Sequence: MAKQIKKIAVLTSGGDAPGMNAAIRGVVRAALNEGLEVYGVQDGYYGLYTDRVIPLDRRSVSETINRGGTFLGSARFPQFKDPDVRKKSVETLKKYDIDALVVIGGDGSYMGAKLITEEFGYPCIGIPGTIDNDIVGTDYTIGYQTALETAVEAIDRLRDTSTSHQRISIVEIMGRHCGDLTISAALASGCEYIIVPEKGLDKESLMRNIEDGFNKGKRHAIIAITELMTDVQALAKEIEDRFGHETRATVLGHIQRGGAPCPFDRILASRMGVYAVDLLLQGHGGRCIGIKNENLVHHDIIDAINNMRRPFKEELFEAARKLF
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G3P2_STAAS
Sequence: MSTNIAINGMGRIGRMVLRIALQNKNLNVVAINASYPPETIAHLINYDTTHGKYNLKVEPIENGLQVGDHKIKLVADRNPENLPWKELDIDIAIDATGKFNHGDKAIAHIKAGAKKVLLTGPSKGGHVQMVVKGVNDNQLDIEAFDIFSNASCTTNCIGPVAKVLNNQFGIVNGLMTTVHAITNDQKNIDNPHKDLRRARSCNESIIPTSTGAAKALKEVLPELEGKLHGMALRVPTKNVSLVDLVVDLEKEVTAEEVNQAFENAGLEGIIEVEHQPLVSVDFNTNPNSAIIDAKSTMVMSGNKVKVIAWYDNEWGYSNRVVDVAEQIGALLTSKETVSAS
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase 2, GAPDH 2, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYK_LISIN
Sequence: MSNENHEELNDQLIVRREKVDTLREEGIDPFGEKFIRSISPEEIETKFADKSKEDLEEAAIEVSVAGRIMTKRVKGKVGFTHIQDRFHQLQIYIRKDAIGEDAYAIFKLADLGDIIGIKGTIFRTNTGELSVKATEFTLLSKSLRPLPDKYHGLKDVEQRYRQRYLDLITNEESQNRFVMRSKILKYTRDYMDNQGFLEVETPVLHTIAGGAAAKPFITHHNALDMELYLRIALELHLKRLIVGGMDKVYEIGRVFRNEGTSTRHNPEFTMLESYAAYEDYEDVMDLVEGLVSTVCKQVNGTTKITYGEYDVDLTPNWRRIHMADAVKEYVGVDFWNVTSDEEAHELAKKHDVAVTEHMTYGHILNEFFETYVEEKLIQPTFVYGHPVEISPLAKKNKEDERFTDRFELFIVGREHANAFSELNDPIDQRERFEAQMKEREQGNDEAHGMDADFLEALEYGLPPTGGLGIGIDRLVMLLTDAPSIRDILLFPTMKHRD
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7L_STAAC
Sequence: MSDYLSVSALTKYIKYKFDQDPHLQSVLIKGELSNFKKHSSGHLYFNVKDKESVISAMMFKGSASKLNFEPKEGDEVLLEARVSVFERRGNYQIYVNKMQLDGIGNLYQKLEALKKKLTEEGCFDKANKKSIPKFPKKIAVLTASTGAAIRDIHSTINSRFPLAEQIQISTLVQGEKAKDDIIEKIEYADSLGVDTIIVGRGGGSIEDLWNFNEEAVVRAIYNCKTPIISAVGHETDFTLSDFAADIRAATPTQAAVIATPDQYELLQQIQQYQFTLTRFIKKHLEQQRKHVEHLSSYYKFKQPTLLYDQQIQRRDDLEKRLKQQIQATFEQQRHRLMLLQQRYNLKALLSSVNQEQQNNLQLTNQLVKLLNSKILSYKNDLKNKVENLNNLSPTNTMLRGYAIVNKKDEVITSTKDLTENDQLTLTMKDGLVDAKVTKVRCNND
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_NICSP
Sequence: MRIDPTTSGSGVSTLEKKKPGRVVQIIGPVLDVAFPPGKMPNIYNALVVQGRDSVGQPINVACEVQQLLGNNRVRAVAMSATDGLTRGMEVIDTGAPISVPVGGATLGRIFNVLGEPVDNLGPVDTSTTSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEENIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLDAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQRVKQTLQRYKELQDIIAILGLDELSEEDRLLVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGNIDEATAKAMNLEMESNLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: SURA_SALPA
Sequence: MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAGQAGQQLPDDATLRHQILERLIMDQIILQMGQKMGVKITDEQLDQAIANIAKQNNMTMDQMRSRLAYDGLNYSTYRNQIRKEMIISEVRNNEVRRRITVLPQEVDALAKQIGTQNDASTELNLSHILIALPENPTSEQVNDAQRQAESIVEEARNGADFGKLAITYSADQQALKGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGQSQSISVTEVHARHILLKPSPIMNDQQARLKLEEIAADIKSGKTTFAAAAKEYSQDPGSANQGGDLGWATPDIFDPAFRDALTKLHKGQISAPVHSSFGWHLIELLDTRKVDKTDAAQKDRAYRMLMNRKFSEEAATWMQEQRASAYVKILSN
What is the function of this protein?
Chaperone involved in the correct folding and assembly of outer membrane proteins.  Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins.  May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
What are the official names of this protein?
Chaperone SurA, Peptidyl-prolyl cis-trans isomerase SurA, PPIase SurA, Rotamase SurA.
What are the subcellular locations of this protein?
Periplasm. Note=Is capable of associating with the outer membrane.
Protein: MUTS_ROSDO
Sequence: MTVTPMMAQYLDLKAEYADALLFYRMGDFYEMFFEDAVAAAEALDIALTKRGKHDGADIPMCGVPVHSAEGYLLTLIRKRFRVAVCEQMESPAEAKKRGSKSVVKRDVVRLVTPGTLTEETLLDARRNNYLTSFAQVRDAKALAWTDISTGAFHVMPLTALKLGPELARLAPSELICSESAENDLREVAEDFGIALTGLARAAFDSTSAEQRICDLFGVETLDSYGSFTRAEVAAMGGIIQYLDITQKGKLPLLRPPQRETENRTIQIDAATRRNLELTQALSGGRAGSLLAVIDRTITAAGGRLMSARIASPSRDLETITNRLDAVSFAQDHHDLCGALRDHLRKVPDLDRALSRLSLDRGGPRDMAAIRNGLTQSAILFETLGSHELPPLLADALNDLSRHDNLIDRLDATLVAEPPLLARDGGFIATGFDAELDEARSLRDEGRSVIARMQQEFAALTGITSLKIKHNNVLGYFIETTATHAEKMLSPPMSETFIHRQTTANQVRFTTVELSELETKILNAGGRALEIEKRLYETLKSDILACSARIAQTASALAELDLTTALATLATTDGWVRPKVDDSRAFAIENGRHPVVENALRQQSGDPFIANDCDLSAEEDAAQIYLLTGPNMAGKSTYLRQNAIIALLAQMGSFVPASCAHIGLISQLFSRVGASDDLARGRSTFMVEMVETAAILNQADDRALVILDEIGRGTATYDGLSIAWATLEHLHDVNKSRALFATHYHEMTALAGKLPGVENATVTVKEWEGEVIFLHEVKMGAADRSYGVQVAQLAGLPPAVISRARAVLDMLEKGEREGGATQKTLIDDLPLFSVAPAPAPAPAKTSDVEARLAEIHPDELTPKQALELLYQLKEAANP
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: GLMM_LACP3
Sequence: MTKYFGTDGVRGIANKELSPEMAFRLGRTGGYVLTQHKEDASRRPLVLVARDTRISGQMLADALIAGLLSVGIEVLDLGVITTPAVAYLIKIQGADAGIQISASHNPVADNGIKFFGADGYKLSDDTEEEIEALLDAPEDKLPRPAAEGLGTVDDYPEGALKYTQFLEQTLADDLSGIHVCLDGANGATSGLVSRIFADLETDFDTMAISPDGLNINANVGSTHPQALSKFVVEKGADVGLAFDGDGDRCIAVDEQGNIVDGDKIMFILGSYMKSQGRLKQDTVVTTVMSNLGLYKALEANGMKSVQTAVGDRHVVEAMRKDGYNIGGEQSGHVILFDYHNTGDGMLTGIHLLNVMKKTGKKLSELAAPVQDYPQKLVNVKVADKENWQAYPEIQSAIDTVEKEMAGDGRVLVRPSGTEPLLRVMAEAKTEDLVSRYVDQIVDVVKQEMGSKED
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RL29_FRATT
Sequence: MKRKDTLKDYRGKSIDQLQEAKIELLQQLFSLRMQKGTGQLKKNHLFKSAKRDIARINTIISEKNK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: NTAQ1_XENLA
Sequence: MEQAAGEPSPFLVRSDCLYTSCYCEENVWKLCEYIRDHRPCLLEQFSAVFISNENKMIPIWKQKSAKGDGPVIWDYHVILLHESARDGNFVYDLDTILPFPSPCNTYIREALKCDSNIHCDFRRKLRVVGAHEFLQTFASDRSHMRDSSSNWTKPPPPYPCIQSAESTMNLDDFISMNPEVGWGTVYSLAAFTERFGDTTLASH
What is the function of this protein?
Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation.  Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule.  Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position.  Does not deaminate acetylated N-terminal glutamine.  With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity.  In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.
What are the official names of this protein?
Protein N-terminal glutamine amidohydrolase, Protein NH2-terminal glutamine deamidase, N-terminal Gln amidase, Nt(Q)-amidase, WDYHV motif-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the NTAQ1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: RT29_BOVIN
Sequence: MLKGMTRLVSRVHKLDPGRFSHLGTQAPQCPVAHLDNQVPTERTRAISRTLENDPAKHGEQHVGQHYNISIQELKTVFPHGLPPRFVMQVKTFNEACLMVRKPALELLHYLKNTNFAHPAVRYVLYGEKGTGKTLSLCHIIHFCAKQDWLILHIPDAHLWVKNCRDLLQSTYNKQRFDQPLEASIWLKNFKTANERFLSQIKVQDKYVWNKRESTEKGSPLAEVVEQGIMRVRNATDAVGIVLKELKRQSSLGVFRLLVAVDGVNALWGRTTLKREDKSPITPEELALIYNLRKMVKNDWQGGAIVLTVSQTGSLFKPRKAYLPQELLGKEGFDTLDPFIPILVSNYNPKEFEGCIQYYLENNWLQHEKAHTEEGKKELLFLSNRNPGLLERLCAYL
What is the function of this protein?
Involved in mediating interferon-gamma-induced cell death.
What are the official names of this protein?
28S ribosomal protein S29, mitochondrial, MRP-S29, S29mt, Death-associated protein 3, DAP-3.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS29 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: BIOF_ALKEH
Sequence: MNAGALSRMLSEGLAARRAEGLYRSPRVLKSVDGACGLTADGRTVVVFCANDYLGLASDPRPGRVMARVAEEQGAGSGAAHLVSGHRPEHEALERALADWTGREAALLFSTGYMANLGVIDALVGRGDTVFEDRLNHASLLDGARLSGARLRRYRHGDVDHLARRLAEDGGRHRLIVTDGVFSMDGDRAPVAELARLARDHGAWLMVDDAHGLGVLGEKGGGLLEQSGLDQDDVPVLVGTLGKAVGSFGAFVAGRRLLIDHLVQSARTWIYTTAPSPAQTAATVEAVRLARHETWRREHLRALVRRFRAGIADLGLDLMPSETPIQPIVVGEADQALQASRALEERGYLVTAIRPPTVPKGTARLRVTLSAAHTPQQVDGLVAALGQVLGQ
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: SYK_SHELP
Sequence: MTEQTQDENKLIAERRAKLDHVRASCPANGHPNNFDRKHKAADIQAEYGQYSKEELEEMNVQRSIAGRIMAKRGPFLVIQDVSGRIQAYAGKDVQKDLKAKYQGLDIGDIIGVTGQLHLSGKGDLYVNMEEYQLLTKALRPLPEKFHGLTDQETRYRQRYVDLIVNEESRAAFIMRSKVVTAIRNFMVSKEFMEVETPMMHSIPGGASARPFITHHNALDIEMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGLSPRHNPEFTMMEFYMAYADYKDLMDLTEEMLSSIAKDLLGDTKLPYGEHTIDFGGPYERLSMLDAIKKYNPDNETIQSMTYEEVKDVEFMRNLAKSLGMTIEKFWTCGQLLEEIFGETAEPKLMQPTFITGYPADISPLARRNDENHFITDRFEFFIGGREVANGFSELNDAEDQDKRFKAQVDAKDAGDDEAMFYDADYITALEHGLPPTAGQGIGIDRLVMLFTNTHTIRDVILFPAMRPQG
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_RHILO
Sequence: MFTLLVDFADKISVFNVFRYITFRTGGALITSALIVFIFGPTIINSLRLRQGKGQPIRADGPQTHFKKAGTPTMGGLMILSGIIGSSLLWANLSSIYVWVVLLVTLGFGSIGFYDDYLKVTKQSHLGFSGKARLGLEFIIAGIAAWVIMHNGQAPFSSSLTFPFAKEFIINLGWFFIPFSCFVIVGAGNAVNLTDGLDGLAIVPIMIAAASFGVIAYLSGNAVFAEYLQIHFVPGTGELAVVLGAVIGAGLGFLWFNAPPAAIFMGDTGSLAMGGLIGTVAVATKHEIVLVIVGGLFVVEILSVIIQVGYFKMTGKRVFLMAPIHHHFEKLGWTESQVVIRFWIIAVILALVGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FUCO_MACFA
Sequence: MRAPGERWRPAGAALWLLLLLLLLGATESVRRAQPLRRYTPDWPSLDSRPLPSWFDEAKFGVFIHWGVFSVPAWGSEWFWWNWQGEGRPQYQRFMRDNYPPGSSYADFGPQFTARFFHPEEWADLFQAAGAKYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYGLYHSLLEWFHPLYLLDKKNGFKTQYFVGAKTMPELYDLVNSYKPDLIWSDGEWECPDTYWNSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSIDKFSWGYRRDMAMSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLALGKWLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTKIMMLRIQGDLKWSTDPDKGLLISLPQLPPSAVPAEFAWTIKLTGVK
What is the function of this protein?
Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
What are the official names of this protein?
Tissue alpha-L-fucosidase, Alpha-L-fucosidase I, Alpha-L-fucoside fucohydrolase 1, Alpha-L-fucosidase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 29 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: Y1373_STRZJ
Sequence: MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAVRHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS
What are the official names of this protein?
UPF0291 protein SPJ_1373.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GDF8_RAT
Sequence: MIQKPQMYVYIYLFVLIAAGPVDLNEDSEREANVEKEGLCNACAWRQNTRYSRIEAIKIQILSKLRLETAPNISKDAIRQLLPRAPPLRELIDQYDVQRDDSSDGSLEDDDYHATTETIITMPTESDFLMQADGKPKCCFFKFSSKIQYNKVVKAQLWIYLRAVKTPTTVFVQILRLIKPMKDGTRYTGIRSLKLDMSPGTGIWQSIDVKTVLQNWLKQPESNLGIEIKALDENGHDLAVTFPGPGEDGLNPFLEVKVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGECEFVFLQKYPHTHLVHQANPRGSAGPCCTPTKMSPINMLYFNGKEQIIYGKIPAMVVDRCGCS
What is the function of this protein?
Acts specifically as a negative regulator of skeletal muscle growth.
What are the official names of this protein?
Growth/differentiation factor 8, GDF-8, Myostatin.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYNS_MARMS
Sequence: MKKIDVTEAIFAIKKEKNLTWEAIADAVGMTDVWITSACLGMNSCTEEVAEKLVAFLGLPAEAKSVLMEYPTKTWDEAIPQDPLIYRLYEVVGVYGPTLKEVIQEKFGDGIMSAIDFSMKVDKEENPKGDRVILTMNGKFLPYKSW
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: FSLD_DICDI
Sequence: MINKFKFYLIFLKLILILVNCQNSLNDYGFGIVDESSICTSYIGDELCKNRLSNSESIYTTPGGGGGGGIDKLSQISTLPILQKGFQSLTFSQGICKDLNFIEFGMCDSALSPCIETTPKITPGYNISLPQRVCKSVCERMLIGCPQLAIQIDCSISFLFPKIGTFYNLTKYGYTANGGMYMVPCIDTEINYEKNKVQENVGFLESCPYPLLLKNSTDPQYAEKRGYTYLTPTNCVLPCPIPNYTKRQMDSVINMSKAMSSISFVLSLFNVITFGLLIKKKSKYNVCIALMAIGSSFIYLSDIINYGVGIEKQLCPEPGRVATQRVDSLCGFTGSIFHIGITLCVLWSMTMGIVLYSKIKQFKLPNFRYFLIGNLSFTVVTLIILASAKKFQGGNGFLECWMRDRWYVVAIFWIPCGIALLLGVLSICGVIFEIYKISKNVSLKDSKVVIRELKPFVLVVTVSASLIYLFVFYFDSESKYDFYKKGVEDYILCLLTSENPLDECYTVGPNFNSYFMFYFLIRFFGILFFGIFGTSEIARNAWTESFFVTKIKSKISITTVSSSTRGGGGDTSGIKSSSSSSNSGVCNNNNSTRKNYGDDFNSKNLSQPDNTIITNNNNNDNNNKMEIELDSIDI
What are the official names of this protein?
Frizzled and smoothened-like protein D.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TYSY_VIBVU
Sequence: MKQYLELCRRIVDEGHWVENERTGKRCLTVINADLTYDVANNQFPLVTTRKSFWKAAVAELLGYIRGYDNAEDFRKLGTKTWDANANLNDAWLNNPYRKGEDDMGRVYGVQGRAWAKPDGGHIDQLRKIVDDLTRGVDDRGEILNFYNPGEFHMGCLRPCMYSHHFSLLGDTLYLNSTQRSCDVPLGLNFNMVQVYVFLAIMAQITGKKPGQAFHKIVNAHIYEDQLALMRDVQLKREPLQAPTFHINPEIKSLEDLETWVTLDDFWVEGYEHHDPIQYPFSV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRCK_CAEEL
Sequence: MAEPPPDDSAPVRLKTLENIYMDGPSKKPEALSFETLIDSLICLYDECCNSTLRKEKCIAEFVESVKTVISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLDFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIRDSNPPYVPEVSSPEDTSNFDVDVCEDDFTPCLQETQPPRVLAAFTGNHLPFVGFSYTHGSLLSDARSLTDEIRAIAQRCQGDAELMEKSVDGFMVELENEKAELVQKLKEAQTIIAQHVAENPRSEEDRNYESTIAQLKDEIQILNKRLEDEALAQQQQKPKDEIVAESEKKLKELKERNKQLVMEKSEIQRELDNINDHLDQVLVEKATVVQQRDDMQAELADVGDSLLTEKDSVKRLQDEAEKAKKQVADFEEKLKEIETEKIALIKKQEEVTIEARKSVETDDHLSEEVVAAKNTIASLQATNEERETEIKKLKQRMDEERASHTAQSEQEMKQLEAHYERAQKMLQDNVEQMNVENRGLRDEIEKLSQQMAALPRGGLNEQQLHEIFNWVSEEKATREEMENLTRKITGEVESLKNNSPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQRQLQAEIDAKLKLKAELKNSQEQYLTSAARLDDTEKRMASLMREVAMLKQQKNIENSSDSAFSSTMGRGDLMISMNNDYEMSNSSLMRQEMISRQSTPSYENAILLHDHQVPKRVDDLRYKQKPMKTASGIFSPVSISAMERGHNFERMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYACHVSCAERVSQSCPVPEEERRPLGIDPTRGVGTAYEGLVKTPRAGGVRKGWQTAYVVVCDFKLYLYDCTVDRQNKMQDVKNEIRLVLDMRDPDFTVCGVSEADVIHAQKGDIPKIFRVTTTQILNSSSEYSSSSKFYTLFMAETEEEKRKWVVALSELKTLLRRSKLADRKAFLVKEVFDVTTLPSIRVAQCCAIIDRSKIVIGFSDHGLYCIEISRQLLIPVGGEKENKQRCVETVEYDEAEQLLMMIVGPAKDRHVRIVPSAALDGRDLKWIKVNDTKGCHLLAVGTNNPGGRAGFFAVAFKKSVTIFQIDRSEKRHKKWKDLAMPGTPQSIAIFNGRLYVGFSHSFRSWSLVGVDSSPVGSGDASGAVLQHISLVNMEDTSLQFLNQQTSYEAKLIVNVPGSPDEYLLVFNMIGLYVNEMGRRSRLPEVMFPTQAKYFAYHEPYLCVFSENEVDIFNVTLAEWVQTINLRSAKPLSGDGILSTCLCNDSPIFVLLQNVLQDQDSIEVPVNLASGSTDGRKVTRRKFTFRTIGKDDRSASERRSHIQISTPSDFMHIVHMGPAPVMELQQNFIDLQSNHSHTSSDKDSLNRSVNND
What is the function of this protein?
Serine/threonine-protein kinase that may phosphorylate and inactivate the phosphatase mel-11, and thereby contribute to the regulation of myosin II contractility during embryonic elongation (PubMed:19675126).  Involved in controlling canal length and Golgi/ER integrity during excretory canal elongation (PubMed:25743393).
What are the official names of this protein?
Serine/threonine-protein kinase mrck-1, Myotonic dystrophy kinase-related CDC42-binding kinase homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Forms parallel punctate bundles in dorsal and ventral epidermal cells.
Protein: YOBA_ECOLI
Sequence: MASTARSLRYALAILTTSLVTPSVWAHAHLTHQYPAANAQVTAAPQAITLNFSEGVETGFSGAKITGPKNENIKTLPAKRNEQDQKQLIVPLADSLKPGTYTVDWHVVSVDGHKTKGHYTFSVK
What are the official names of this protein?
Protein YobA.
What is the protein family that this protein belongs to?
Belongs to the CopC family.
What are the subcellular locations of this protein?
Periplasm.
Protein: AT1A4_MOUSE
Sequence: MEPGKEKEVEAPGELNQKPRPSTRSSTTNRQPKMKRRKKDLEELKKEVVMDDHKLTLDELSAKYSVDLTKGLSILEAQDILFQNGPNVLTPPPTTPEWVKFCRQLFGGFSLLLWTGACLCFLAYGIHVNYYKENANKDNLYLGIVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRDGEKMQINVRDVVLGDLVEVKGGDQIPADIRVISAQGCKVDNSSLTGESEPQSRCPDCTHENPLETRNIIFFSTNCVEGTARGIVIATGDYTVMGRIASLTSGLQMGKTPIATEIEHFIHLITAVAVFLGVSFFWLSIILGYTWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHLWFDKTVYEADTSEEQTTGKTFPKSSDTWFYLARIAGLCNRADFKPHQESVPIAKRATTGDASESALLKFIEQSYNPVSEMRQKNPKVAEIPFNSTNKYQMSIHLLEDNSEAHVLLMKGAPERIFDFCSSFLLNGQEYPMDEEMKMDFQNAYIELGGLGERVLGFCFLNLPSNFSKGFQFNTDELNFPMENLCFAGLISMIDPPRTAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKSVGIISEGNDTAEDIAARLNIPISQVNNKSVKAIVVHGSELKDMESQQLDDILKSYKEIVFARTSPQQKLIIVEGCQRLGAIVAVTGDGVNDSPALKKADIGIAMGITGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIILSIPLPLGTITILCIDLGTDMVPAISLAYESPESDIMKRLPRNPKTDNLVNNRLIGMAYGQIGMIQALAGFFTYFVILAENGFKPLDLLGIRLYWDDTQLNDLEDSYGQQWTYEQRKVVEFTCQTAFFISIVIVQWADLIICKTRRNSLFKQGMKNKILIFGLLEETVLAAFLSYVPGMDVSLRMYPLKINWWFCALPYSVLIFVYDEIRKLIIRRRPGGWLEKETYY
What is the function of this protein?
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane.  This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.  Plays a role in sperm motility (By similarity).
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit alpha-4, Na(+)/K(+) ATPase alpha-4 subunit, Sodium pump subunit alpha-4.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RMD9_LODEL
Sequence: MFRLVNTSQGLRPALISKFKHAKTGGTNPSPFSTTTTNAPTNTTPTSNSKYESTFQFKRAQSTVAPPATVATTIQTPSSQNAAANPYRSKLDSFSRIYHVPNHVVGRRTEKIDHTATDEMATLILDENFRNQMTETDLYRYAASIYSAAIAVRRQRLEMSRNRDRDNAASFGDDLKYQSAAIALAESIAAGEFPQQVSARTLFKVFATLMQFKLNDEIMNLWETGVAQSEGEDLGDIGKMYLDHTVLSVVLEVAYDSKRFSYEEILRIYEMSLVENEPIHPYLLERIGQIAIKHGDHARGLDCLEQLMNNYENNPRARSILGALSQIHIAFIGNCKDTIIAKRFFEKAVDESDHLPYTILLKAPYVVSFLQNCNALGDSFENIVDMWSRVCQFYIKRREEQPSRMVTINSGLFKILFDKYPEPSMEAMKLMKLTFAKCKNINEHFLNTLISHMPWKDRTLVNDVVSAYDKFKVPKSVVSHRIILKNAGNVEYTPEEILTLWNQLLLKLDSEGYKYIANADWAAIRLATIFSEQFKSPERDCLYYSIVRTYKNYMQHDEAALRFLRATVRDATVYKQISRITTEENPTFEINYDIEVPEFKNLKENTNYPKVTKKVTDANPNLL
What is the function of this protein?
Binds the 3'-UTR of mitochondrial mRNAs.  Involved in the processing or stability of mitochondrial mRNAs.
What are the official names of this protein?
RNA-binding protein RMD9, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RMD9 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.