PharMolix/UniProtQA huggingface dataset:
Protein: RRF_MYCPN
Sequence: MSPEKYLNFFKETADKKFQWLKEELSKIRTGRPNPKLFDNLLVESYGDRMPMVALAQIAVNPPREIVIKPFDVKNNINAIYSEIQRANLGVQPVIDGDKIRINFPPMTQESRLESIKQAKKVVEQIHQELRSVRRDTLQMIKKDDHKDEDFEEFLKEEVEKVNKQYIAQLETIQKQKEKELLVV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_RICFE
Sequence: MILVNVHAGNCDNTLKNFKKRLQRELYFRKMKEQRYYETPSAKRVRKAQEAARRQRKFARKKMFDE
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: METK_SHEON
Sequence: MAKHLFTSESVSEGHPDKIADQISDAVLDAILAQDPKARVACETYVKTGMVLVGGEVTTSAWVDIEELTRKTVREIGYIHSDMGFDADSCAVLNAIGKQSPDINQGVDRADPKEQGAGDQGLMFGYASNETDILMPAPITYAHALVKRQSEVRKNGTLPWLRPDAKSQVTFAYEDNKIVGIDAIVLSTQHSPDIAQADLIEGVMETIIKPVLPAQWLNKDTKYFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSISVETFGTGKVSEEVLIKLVRQHFDLRPYGLTEMLNLARPIYQATAAYGHFGRSEFPWEATDKAEALRADAAL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BUB1_DICDI
Sequence: MSSLSDWENTKENIVPLKTGRDPTKLALFAKQTNQSDEELEKEKQKFEIIINEYQGEDPIDNWLKYIKWVQQSYPGGNMKEQLIVLLERCTRLFLSTEKYKNDPRYLRIWITYADMCRDPIEVFSFLEVQRIGFYLSLLYEARAIVYENKGNYEQADKSFKQGIERKAQPIERLQQKHLDFERRLIARLKHQQQHQQLQQQQQQQNDQLEQQQLDENGNTKLTRSALGTISSSSVHSERKSQQTKGLPLGNSTIDKKRKVGNDQKNNLGFQIFDDEKGGSTTNEVLTDSKFFGSSRKAAALMAAGQTQQTSQMKWDELEPELNKHKENTQLSQKWSDVKLLQKKQKITTAGFQIYCDQDSLSNNNNGSNNNNNNNNNENIPLSPDKLRVHSSKQQSKLEQIQNNPLANFPKVSTSNSSSSSSSSTNKSTSTTTVTTTKNERVGYNKPLFTKENEKHEISFEEYRASLFKKKLIEKQEQQNKKIEKEKEELDIKLKQEQKEQKEKEQKEKEQKEKEELEIKLKQEQQEKELQYQQHQQKQYQQKQQQQQSYNPPSPTMTIHTKQAFHDVMAMFSEPLEFEKNNKSTSSSSSLQLNNVPSSPNPFTESTLMKSTIDNNKNDNNNNNNNNNNNNNNKNTDVSFDEKSIEDQENIDPNQGGGGGNNDGNPLLSSKITNRDVLMKQLFSKDEDEGNQFDQERDMVKTIERIDLLVKGKDTPKFEIFEDSTLASSQLHSKSVSLADKVASKNKQLNPLEQSQNPLKKSILGSSGINGINGNNGGFTIFQDQPNQEKKQPLQQSQLQNPLKNSILGISDANGNGGGGGSGSGSGGFTIFQDQAAEEKKPFNEKEQQQQEEKEKENKIEEEEEEEEKDKEKEINYQNITGNITSTIDPTTVIICSLTPDDGIVNPYLIDHQYLLEQHVSATVQSIQSFFNVGDDLAPLPEQLDQCEPNQLFEDNSIIVQWPFSDITVNFTKCVCKSTMDGSMTFKVERIDDLAMTTSEDSWLSCKVQDPPSIWEFYIGNQIHQRLQERSLTISNSKFPTIHSLYYYTDKSIMLMDHTIDQGTLDDVVSSTNGVPMEEPLAMFHCIELLKMIEDLHLVGIIHGNICANNLHFLFGQTSDWPDWTAGECKGAWKSKGFTLTDFSRSIDTTIYSQDARYQSPIELLPIGTPLEWLKINQSSTTNVGWSYNLDYLGICKVMFHILTCGKEELKLSLSQQTGKLEIINQSIIQKDSFSELDTLWLPFLTTLLNHNGENGNQQTTTTTYILKQQRNLFENYLQSNPVKSKIKSLLRIQNIKLFESMKSKQ
What are the official names of this protein?
Probable inactive serine/threonine-protein kinase bub1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. BUB1 subfamily.
Protein: TRUB_BRUSI
Sequence: MARRGKKKGRPISGWVIFDKPKGMGSTEAVSKIKWLFSAEKAGHAGTLDPLASGMLPIALGEATKTVPYVMDGTKVYRFTVTWGEERSTDDLEGQPTKTSDKRPSREEVEALLPDYTGVISQVPPQFSAIKIDGERAYDLAREGETVEIPAREVEIDRLEIVGFPDADRTEFEVECSKGTYVRSLARDMGRDLGCYGHISDLRRVEVAPFTDEDMVTLAKLEAVWPPLPPKDEDGNVIEPAPRRDFSALDALVIDTGAALDCLPQVPLSDDQAQRVRLGNPVILRGRDAPLEADEACVTTRGKLLAIGYIEHGQFKPKRVFTAG
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: WNT7A_ANSCE
Sequence: SGSCTTKTCWTTLPKFRELGYILKDKYNEAVQVEPVRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEKSPNYCEEDPVTGSVGTQGRMCNKTAQQSNGCDLMCCGRGYNTHQYSRVWQCNCKF
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway (By similarity).  Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development.  Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity).
What are the official names of this protein?
Protein Wnt-7a.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: GLO2_SHIFL
Sequence: MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAITANNWQPEAIFLTHHHHDHVGGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEFSVITTPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTALQMYQSLKKLSALPDDTLVCCAHEYTLSNMKFALSIFPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLRTEDIDLINGINEETLLQQPEERFAWLRSKKDRF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: TAL_RHORT
Sequence: MSETKLDALRRHTIIVADSGDIDAIRSFAPQDCTTNPSLILKAAKMPAYAGLIAQAIEAGSAEAGPSEGLIDRILDHLAVTFGSELARIVPGVVSTEVDARLSFDTQATVARAERLIGLYAARGVAAERILIKVAATWEGIRAVEILQSRGIACNVTLVFSLAQAVAAAEAGAFLISPFVGRILDWHVKASGKSFDIDEDPGVRSVTEIYTYFKHFGYKTIVMGASFRSSAEVEALCGCDRLTVSPALLDQLRSQTGDVPKRLDPAASKAATISRLAVDEASFRWQINEDALATEKLAEGIRLFNADTDALRRTIAETLAKRASTVA
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_SULIA
Sequence: MNTMSHKFVLALDEGTTSARAILFDSDLNIVNIGQYEFPQHYPQPGYVEHDPEEIWEAQMLAVKKAISKIDAKQIVAIGITNQRETTVLWDAKSGKPVYNAIVWQDRRTSPITDWLKANYFKMIKDKTGLVPDPYFSASKIKWILDNVSNVREKAERGEIKFGTIDTYLIWRLTNGKAHVTDYSNASRTMLFNINKLEWDREILELLKIPESILPEVKPSSEIYGYSEALGNLIPISGDAGDQQAALFGQVAFNVGEIKATYGTGSFILMNIGNNPIRSENLLTTIAWGLEKNKAKYALEGSIFITGAAVQWFRDGLRAIDVSDEIEPLASSVEDNGGVYFVPAFVGLGAPYWDPYARGLIIGITRGTTKAHIARAILESMAYQTRDVIEVMQKESSISINSLKVDGGAAKDNLLMQFQADIIGIKVIRPKVMETTSMGVAMLAGLGVGLWNSLEELRSIWKVDKEFIPSMSEEKRRALYSGWKEAVKRAMGWAKVVGGQV
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: PTPN1_MDBVW
Sequence: MVVNCFETCRAIDFWNRRNQLNFPGIVRLEHHQVILKPFNGTWENSEKPENQRKNRYNIRCWDHNRVILKSGSGSTSNYIHANYVDGFEDDKKFIITQGPMEETCNDFWKAVWQNNCSIIVMLTPTKGTNGEELCYQYWSLNEDSNIITEDFVIETVNTSVRPTYILTTLRITDKISNDSRRISHYQYTEWPVDETPTNHVDFIKFIKIININRKKSGSNYQQQLLSPIVVHCSDGVKKTGIFCAVDISLNQLVLRKTVSLAKTAEKIRQQRHSTISTPDDYLILQPGYYVLLYLLYKILAIIKIKNCGEKKSRRKST
What are the official names of this protein?
Probable tyrosine phosphatase protein N1, PTP-N1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
Protein: TRUA1_BACCR
Sequence: MDRIKCTVAYDGMHFCGYQIQPNHRTVQQEIEKALQKLHKGELVRVQASGRTDSTVHAKGQVIHFDTPLSLEEWQWSNALNTMLPDDIVIRQVEKKTEEFHARYGVEKKEYRYRVLLSKTADVFRRNYVYQYPYPLEINSIRKAIPYFIGTHDFTSFCSAKTDKKDKVRTIYEIELIEQDDEIIFRFVGNGFLYNMVRIIVGTLLSVGQGKLDPDSIPEILAKQNRQFAGKMAPGHGLYLWEVNYNN
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A 1, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I 1, tRNA-uridine isomerase I 1.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: COBT_CUPNH
Sequence: MQFPEITPLDDALRPELQAAIDDKTKPLGALGRLESLALQLGLILGTARPVLQRPTVIVFAADHGVADAGVSAYPAEVTAQMVQNFLAGGAAINVFSRQHGIALEIVDAGVRAPLPAAPGLVNCRIADGTRNFAVEPAMTPEQAAAAMTAGMARVLRHAQQGCNVIGFGEMGIANTSAAACLMQRLTGLPLADCIGRGTGLDDAGLARKREVLERALALHADAQAPLDVLATFGGFEIAMMAGAFLAAAASRMVILVDGFIATAALLVAQRLDPNVLQYCVFTHCSHERGHRALLDQFGAAPLLALDLRLGEGTGAALAWPLLASAAAFLNEMATFSGAGVSTASP
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: MUTL_VIBC3
Sequence: MTIRILPARLANQIAAGEVVERPASVVKELVENSLDAGATRIDIDLEKGGAKLIRIRDNGSGIDKDELGLALSRHATSKIHTLDDLEAIMSLGFRGEALASISSVSRLTLTSRTVAQEEAWSAYSEGRDMAVKLQPAAHPVGTTVEVLDLFFNTPARRKFLRTEKTEFTHIDELLKRIALSRFDVSFTLRHNGKIVRQYRAATTLPQQEKRLAAVCGNPFVQHMLRIELEHQGLKLHGWITTPEGARQQSDLQYCYVNGRMMRDKLINHAIRQSYETSLRVDQFATYVLFIELDPHQVDVNVHPAKHEVRFHQARLVHDFIYQALSSALVQGAQVMAPTINEGAFHLPHCAEEVNPPVVPMIDTTQQERVWQAVQNTPDYPRKAPRDNDRDESDNPQVRERAVSNPWVASPKTASTGKERYGSASVSKKEAAVYQTLMQTPDLSDEEPSTASTIVSSIEAVKANIAIEKLGKAIQVVAGQYLLMSSPQGCVLISLYQAQQLKLRGLLNAQHGALKAQPLLVPLALKLNESEWQVAQRHSSALLQLGIELKSRTNHSIMVMAVPQPLRQQNLQQLLPDLLSYAASCSESQALSHQALADWLTQRIVVEKRDYTLAEAIGLIAELEQLWQGNLPLQDPHFITLVDFSASITALHS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: Y1363_METJA
Sequence: MTVMIKKIARKKCIHVMLVYTGGCNACDIEVVNAIFSPFYDAEQYNVFLTFNPREADILVVTGCVTKVVAESLRKIYEKIPEPKAVVAVGACALMGGVYKNIGGDLGTSDFVAGPVENIIPVDVKVPGCAPRPEDIIAGIVKALPKVIEGK
What are the official names of this protein?
Uncharacterized protein MJ1363.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
Protein: HEM3_XYLF2
Sequence: MPLLRIATRKSLLAMWQSEYVAARLRMLCPDLDVVLVPMSTRGDEILDRSLAAIGGKGLFLKELELAMLRGDADCAVHSLKDVPMDLEPPFMLAAVLSRDDPADALISNVYLSLESLPIGARVATSSLRRQAQLRFYRPDLRLFDLRGNVNTRLAKLDNGDYDAIVLACAGLRRLGLEQRMTARLAPPEWLPAPGQGAIAVESLTEDARIGTLLAGLDDLPTRKCVIAERTMNRALHGSCHVPVGAYASYEVGGMRLQGLVGCVADGRLVRAELCSAKDEGDMLGRAVAQCLLDAGAAELLAATA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: CDKAL_DROME
Sequence: MYHLGQDLPGNDVDDIEDLISADDVKPRERYENKKTVTVRAKKRSQIRLESQEEEEKPKPTIHESVIPGTQKVFVKTWGCAHNNSDSEYMAGQLAAYGYRLSGKEEADLWLLNSCTVKNPSEDTFRNEIESGMRNGKHVVVAGCVPQGAPKSDYLNGLSVIGVQQIDRVVEVVEETLKGHSVQLLQNKKKVHGRRVAGAPLSLPKVRKNPLIEIISINSGCLNQCTYCKTKHARGDLASYPPEEVVERARQSFAEGCCEIWLTSEDTGAYGRDIGSSLPELLWQLVEVIPEHCMLRVGMTNPPYILEHLEEVANVLQHPRVYSFLHVPVQSGSDSVLGEMKREYCRQDFEHVVDFLRERVPGVTIATDIICGFPTETEDDFEETMTLCAKYRFPSLFINQFFPRPGTPAAKMDRIPANLVKKRTKRLTDLFYSYEPYADRVGEIYTVLVTEVSHDKLHYVGHNKSYEQVLLPMRDNLLGTRVHVRITSASKFSMVGEILDDERDWTRCAKNQELPNVQVQTRSRERLIQRYFGIALVLGSLAFLIQLVVRLL
What is the function of this protein?
Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
What are the official names of this protein?
Threonylcarbamoyladenosine tRNA methylthiotransferase, CDKAL1-like protein, tRNA-t(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. CDKAL1 subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: XERC_SHIFL
Sequence: MTDLHTDVERYLRYLSVERQLSPITLLNYQRQLEAIINFASENGLQSWQQCDAAMVRNFAVRSRRKGLGAASLALRLSALRSFFDWLVSQNELKANPAKGVSAPKAPRHLPKNIDVDDMNRLLDIDINDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHLDLESGEVWVMGKGSKERRLPIGRNAVAWIEHWLDLRDLFGSEDDALFLSKLGKRISARNVQKRFAEWGIKQGLNNHVHPHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates.  The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.  In the complex XerC specifically exchanges the top DNA strands.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_RUEST
Sequence: MLKTRLIPCLDVADGRVVKGVNFVGLRDAGDPVEAARAYDAAGADEICFLDIHATHENRGTMFDMVRRTAEQCFVPLTVGGGVRTKDDVRALLLAGADKVSFNSAAVANPDVIAEAADQFGSQCIVCAIDAKSVAPGKWEIFTHGGRRETGIDAVEFARLVTAKGAGEILLTSMDRDGTKSGFNLEMTRAISDAVNVPVIASGGVGTLDHLVDGVTKGGASAVLAASIFHFGEYTVQEAKEHMIANGIPMRLQ
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPNE_DROGR
Sequence: MDDLMDFFDSSKNFKRGTLPRGCISGDPNAYTSESSDSKPIKREIIGTKDVNEIVQKEQQLMNQLVGGPSNTKRTKTLDELESDDDDKMELNEAPTVRSDEAFYEKYHFDLNRNRSLPIYAQREQIMKAIKENPVVILKGETGCGKTTQVPQYILDEAFKKREFCNIVVTQPRRIAAISIANRVCQERRWQPGTVCSYQVGLHKQSNSADTRLLYCTTGVLLNNLIRLKTLTHYTHIVLDEVHDRDQDMDFLLIVVRRLLALNSRHVKVILMSATIDTREFCKYFASCKSMPPVVAASHGRKYPLVKYYRDQLKNINWKTEPQQREPGITHEGYRDAVKILLVIDNMERKAEGQSEQSYEEAKRTGSVLIFLPGVNEIDTMAEHIEHVMNESPNIKITIVRCHSLMSSDSQEDVFQPPLSGHRKVILTTNIAESSITVTDVSYVIDFCLAKVMHIDTASNFSCLCLEWASKVNCRQRAGRVGRTRSGRVYRMVTKAFYMEEMQEFGIPEMLRSPLQSSVLKAKELDMGGPSEILALAMSPPNLTDIHNTVLLLKEVGALYTTVDGVYEQLDGDLTYWGTIMSRFPLDVRLSRLIILGYIFNCLDEAIIIAAGMSVRSLYLSGQRQRTSDAFWMHYIFADGSGSDLVGFWRVYKIYVNMCQNLPMKDSEVQWARRYNVSLRSLKEMYLLVQELQKRCAALNLVSLPVGASHMWHDREKSIILKVIIAGAFYPNYFTRNNKTIPDYDRDVYHSICGNDPCRTVYFTQFVPRYMGELYTRRVKELFLEARIPPEKIDVTFQQGSEKIFVTFKGDDDDYMNSTDVVQVPGRVTTEVYKAIRMRMNNPNRSLRVMDQNSALKYVQQRNIGVVQDSKWVPPSKQWNVELLTLPSVFDKKITGLITYIVNCGKFYFQPRSLAERIASMTEIFNAPEQLSYHVRNASAITKGLQLLARRGSKFQRAVVLKVEPQSNAIPQFLVRFIDYGDWALLAMDQLRLMRHELRRDLEELPPRMFECRLALVQPSSVTSYSNRWPQKANEMLSKLASCGPLELEVYSLVNNVAAVLIHMRDGVLNDKLVEHQLARRADEDYMSRKDHDFRIRKQKMKRYVPAAEQQQVNEEYLRFNQLPQDADLEPPPLDKCHTSIRLKGPYSPLENSMNSMLRIGMYKSVAIEKESVNAVLLDADPQDRHDQMIVAASVTESDGNDKLVARGTTLMPNIHGFGALMAMLFCPTMQIKCNPERTKYVCLLAGLGFNPDTLEPYFQEHDMVINLDVGILKDDIRIINQMRYNIDSMFFNFDANELPAVGVEGRLVIFNQLRNLLTRLLGKDRSFIERHVWNSKYVWEDMSDLEPPSEPYGKRAIFPMHGSYDLESEDMGNLLALQENCSELYDWQNFDGVMQPRNCRLCNETLESVTQLRLHLLTQLHRDREKQVGWKQQ
What is the function of this protein?
Probable ATP-binding RNA helicase which plays a central role during spermatogenesis and oogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi and govern the methylation and subsequent repression of transposons.  Involved in the repression of LTR retrotransposon copia.  Also involved in telomere regulation by repressing specialized telomeric retroelements HeT-A, TAHRE, and TART; Drosophila telomeres being maintained by transposition of specialized telomeric retroelements.  Involved in telomeric trans-silencing, a repression mechanism by which a transposon or a transgene inserted in subtelomeric heterochromatin has the capacity to repress in trans in the female germline, a homologous transposon, or transgene located in euchromatin.  Involved in the repression of testis-expressed Stellate genes by the homologous Su(Ste) repeats.  Required for anteroposterior and dorsoventral axis formation during oogenesis (By similarity).
What are the official names of this protein?
Probable ATP-dependent RNA helicase spindle-E, Homeless.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the nuage, also named P granule, a germ-cell-specific organelle required to repress transposon during meiosis.
Protein: CD047_HUMAN
Sequence: MPAEGGKTDMERIGLFSEMEYITVGDKYVSQFNRPFNEAASKNKQMLPGGSKEMSDLQAGYFDPHFVRIFEGEGYINLNQVRRRDMVEAAKKNLGKAFLPSNGEKKPCGLGSYYGTIGGPVPFFSAQSKPREKYKAPGKNLYTNPGKKGTGYGYANITIGKQFSHSADFYDAAKLKYKKANEEHHRLLKGAPFKLNLHPRDYFDANPYFSEESLPPIKKEEKKKTISNTFKPSSPGKKPGGMKAGTFDPYPSHSADPYVAKLANISGKDDKIFHPPSGPKSRPVESIMTLNVRRALNSKNYKTSSVPSY
What are the official names of this protein?
UPF0602 protein C4orf47.
What is the protein family that this protein belongs to?
Belongs to the UPF0602 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: Y136_METHJ
Sequence: MTLRHHFELRETIATILADEELVIETACEGIRTARYELERYIIQDPFFNSSFEPLTITQGPDIIKNMAAAAWKAGVGPMAAVAGAIAHAGVSAAQKKGASFCIIDNGGDIAMITDRPVRVGLYAGNSPLSGKYAFFIPPKNEIYGICTSSATVGHSFSFGTADSVTVFSRDPLLADAVATAVCNVLTIADQSCLDRVDSHIDGIFAVFGEQSIIWGDIPQIIRAENRKDLITAGGLGFFPGTLI
What are the official names of this protein?
UPF0280 protein Mhun_0136.
What is the protein family that this protein belongs to?
Belongs to the UPF0280 family.
Protein: URED_SORC5
Sequence: MRPLAPDARCAPSRPGRGPWYARRPVTTPSDPPAALREPPPPARRAGKAGSGELVFTRVAGRTVLEKALARSPLKLLAPKNHGQAAWVFVASFGGGLVGGDELNLHARVGRGAAALLSTQASTKVYRSPLVSRQRLEAEVQAGGLLVAIPDPVVCFAGSRYEQDIDVALADDASLVLVDALSSGRSARGERWAFDRYASRVRVSRGGRAVLLDATRLDPAHGALPERMGRFDALATLVALGPRAASAAEALLAPRPPPERRAELVASASPLRGGGAVVRVAGTSVERVAGFLRGALAFLAGELGDDPFARKW
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PMI15_ARATH
Sequence: MLNRAMENSDMKRNSSTLLDLPVVKSSLVVEAIHMSRKKLGWYNESRRDSETVKARVEAGLSEVKKSVEELALLIKRSNRSAGFQEKDMEVLKMEEKYAEVMRVLEVVKEEVSRVKLDVSSVLIERVAAEEKVEELRFKTEGGLRLLESLKKEIEVANEEHLMVALGKIEALKGYKEIERQREGKAIKVLDLLVERNKRIKNMLEEAERSKDIEIELFETSTDVEMLETQLKLFKKMERRVQGRDSSSMSRSNRSFGRGKYSLSVLKEVTEGKKEELASVKVEIFRVMTVMDALRNEIIRARDETACLGKILREDDVKIEKLNSKILIEKSKLEVVSIAEERISSLAENFVGSLEKIKKSRNAAKKEEFLFKEEKTVTKAETQKTKLDIDKKESELNSKLDELEKVKHTEALVLEKLESLVEDMMESREMESEHCSTITISRFEYEYLSKHASQAEETAEKKVAAAAAWVEALKASTKSFLMKTETLMRESEMTKAEEEREVFRMERSLSTKRLVEGEIQKIKRNSEAEGYISPKPVGKFTPVQRGKPRRYSSVGTPTFFVIKKKKKVPRLAKFFSRRS
What is the function of this protein?
Required for the chloroplast avoidance response under high intensity blue light.  This avoidance response consists in the relocation of chloroplasts on the anticlinal side of exposed cells.
What are the official names of this protein?
Protein PLASTID MOVEMENT IMPAIRED 15.
What is the protein family that this protein belongs to?
Belongs to the WEB family.
Protein: Y3509_DICDI
Sequence: MDKKINLDYLIDDIIVNSDDLTPFQCQICFNSVIDFKKETLSFDVLQCRNGHISCHECWNRQLSIKQECPSCKVKTLPSELSRNIFLENAFRALKVICPNKFKESKFQGEAVHCENGCPEILKVELLEHHLKECQYQFIKCPNNSNKCKYIIRKNQIEHHNQSVCDYSLIQCEKCSELIERKKLNKHIESECDTLMITCSKCSASIGKKLMNHHLETDCPMEEISCLYKAGGCNKRFLRSQLSQHLSENNNHIFYIQNVMDLHKLQLDECNQDYRKLEKQNRDLEKRLFYLESTVNSTVINSKPHECGGGGGGGSGNNVYKGKWVINNWDRKLREYPISKSLNSPFFQIGSSKFFIMLYPNGNNEVKGFLSIFLYKIYDRPSLVKYSLEAKNIDPTKNYKNTHTNNFINNNGNGWFKWIENKSQNGFFSNNSLTISISIKIIQDHSLVTE
What is the function of this protein?
Probable adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases.
What are the official names of this protein?
TNF receptor-associated factor family protein DDB_G0273433/DDB_G0273509.
What is the protein family that this protein belongs to?
Belongs to the TNF receptor-associated factor family. A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_WOLSU
Sequence: MNSDTLNIGNKIFQSRLIVGSGKYKDFKTTYEATMASEAEMITVAVRRVNITNPKEENLLDYFKGSSVQFLPNSAGCTTAEETITLFRLTREATGIDFIKLEIIGDTQKTLYPDVMETLKACEVLAKDGFTVLAYTNDDPIMARRLEEAGASAIMPLAAPIGSGLGIQNRYNVVFIKEAIKVPLIVDAGVGCASDAAIAMELGADAVLTNTAIAQAQNPILMASAMRDAVRAGRQSYLAGRIPKKPYASASSPTDGMARF
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_ACTP7
Sequence: MRILGIETSCDETGVAIYDEEKGLVANQLYSQIEMHADYGGVVPELASRDHIRKTLPLIQEALKEANLTAADIDGVVYTAGPGLVGALLVGSTIARSLAYAWNVPALGVHHMEGHLMAPMLEDNPPAFPFVALLISGGHTQLVKVEGVGQYEILGESIDDAAGEAFDKTGKLLGLDYPAGVAVSQLAEKGTPNRFVFPRPMTDRPGLDFSFSGLKTFAANTINANLDENGRLDEQTRCDIAHAFQQAVVDTIIIKCKRALQQTGYKRLVMAGGVSANKQLRTDLAEMMKNLKGEVYYPRPQFCTDNGAMIAYTGFLRLKNGETSDLSISVKPRWNMTELPDISTTGG
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.