PharMolix/UniProtQA huggingface dataset:
Protein: GLPB_HAEIN
Sequence: MNFDVAIIGGGLAGLTCAIALQQRGKRCVIINNGQAAIDFASGSLDLLSRMPSTTYGENRAVENLKENITALRNELPAHPYSLLGAEKVLAKAQDFERLANELHLDLIGSTEKNHWRVTGLGSLRGAWLSPNSVPTVQGNEPFPHKRIAVLGIEGYHDFQPQLLAANLVLNPQFEHCEVTSGFLNIPQLDELRKNAREFRSVNISQLLEHKLAFKDLVKEIIESAQGAEAVFLPACFGLENQEFMTALRDATKLALFELPTLPPSLLGMRQRIQLRHKFESLGGLMINGDSALNATFEGNQVRCINTRLLEDEEITADNFVLASGSFFSKGLISEFDKIYEPVFESDIIGVEGFNNKDRFTWTAHRFAHPQPYQSAGVAINAQCQVKKCGQFLTNLYAVGNVIGGFNALELGCGSGVAVVTALAVADEILAK
What is the function of this protein?
Conversion of glycerol 3-phosphate to dihydroxyacetone.  Uses fumarate or nitrate as electron acceptor (By similarity).
What are the official names of this protein?
Anaerobic glycerol-3-phosphate dehydrogenase subunit B, Anaerobic G-3-P dehydrogenase subunit B, Anaerobic G3Pdhase B.
What is the protein family that this protein belongs to?
Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
Protein: HIBCH_RAT
Sequence: MGQQFVWRLQSRFSSIRRASVILQHLRMSKHTETAEVLLERRGCAGVITLNRPKLLNALSLNMIRQIYPQLKKWERDPDTFLIIIKGAGGKAFCAGGDIKALSEAKKAGQTLSQDLFREEYILNNAIASCQKPYVALIDGITMGGGVGLSVHGQFRVATERSLFAMPETGIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVHRAGIATHFVDSEKLHVLEEELLALKSPSAEDVAGVLESYHAKSKMGQDKSIIFEEHMDKINSCFSANTVEQILENLRQDGSPFAMEQIKVINKMSPTSLKITLRQLMEGSTKTLQEVLTMEYRLTQACMEGHDFHEGVRAVLIDKDQTPKWKPADLKDVTDEDLNSYFKSLGSRDLKF
What is the function of this protein?
Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite.  Has high activity toward isobutyryl-CoA.  Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism.  Also hydrolyzes 3-hydroxypropanoyl-CoA (By similarity).
What are the official names of this protein?
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, 3-hydroxyisobutyryl-coenzyme A hydrolase, HIB-CoA hydrolase, HIBYL-CoA-H.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GATC_POLSJ
Sequence: MALTSQDIARVANLARLELRPEETEHTLSQLNGFFALVEQMAAVNTDGVEPLAHPAAVIGEVALRLRDDIASEPNQREASQVSAPAVERGLFLVPKVIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: PSY2_ARATH
Sequence: MSFGTRLLLFLILTLPLVTSSSPNTLHVSGIVKTGTTSRFLMMTIEDYDDPSANTRHDPSVPTNAKADTTP
What is the function of this protein?
Promotes cellular proliferation and expansion.
What are the official names of this protein?
Protein PSY2.
What is the protein family that this protein belongs to?
Belongs to the sulfated-peptide plant hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYSN_ALIF1
Sequence: MNSAVEQQLAELGIEAYLKEHQYKSLLRFLTCGSVDDGKSTLIGRLLHDSKQIYADQLDAVHADSQRVGTTGERPDLALLVDGLQAEREQGITIDVAYRYFSTQKRKFIIADTPGHEQYTRNMATGASTCNVAVILIDARKGVLDQTRRHSYIANLLGIRHFVVAVNKMDLVEYSQSRFEEIKEEYLAFSKKLNNPNLDISILPLSALEGDNVVNPSDALSWYQGEPLLEVLENVDIDADKGNGEFRFPVQYVNRPNLDFRGFAGTVSSGGISVGDEIVALPSGKKSKVARIVTFDGDLTSAQAGQAVTLTLEDEIDISRGDLLVKSQSNLQATDQFKAEIVWMTEKGLEPGRQYDIKIAGKKTVGQIDAIHHQVNINSLEKFDTQELPLNGIGLCDVSLTETVSLDRYQDCADTGGFIFIDRLTNVTVGAGMIQNLSDLSESKPINDNISAFEIELNALIRKHFPHWETKDISKLLG
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: RL16_EDWI9
Sequence: MLQPKRTKFRKVHKGRNRGLAQGTDVSFGTFGLKAVGRGRLTARQIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLAVRMGKGKGNVEYWVALIQPGKVLYEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: FB281_ARATH
Sequence: MTIMSDLPRDLLAEILSRVPLTSLRAVRLTCKKWNDLSKDRSFLKKQIVETKKKQLESKEIEVIMMRNFRVYLTSIDIHNNVDPSFTPKGTLISLSDDANHHQVDNVSRVFHCDGLLLCITKDLHYRLVVWNPYFGQTRWIQPRNSYHRKDNYALGYDEKKNHKILRLKDNYYAPRERICEFELYSFESNSWKVVLDVSPDWYIPSYNRGLSLKGNTYWYATEKHVNVDFLICFDFTTEKFGPRLPLPFNATESPTYEDVVTLSSVGEEQLAVLFQSEYTLMMEIWVTSKVESTEVLWNKLFLEVDLIAISSHFQFLAEAGSFFIDQKKNVVVVFDKDMDEATDRDMAYVVGKNGYFKKVDIGEEAYTSCFPLVCSYVPSSEQIRQLT
What are the official names of this protein?
F-box protein At5g42460.
Protein: XER_CLOAB
Sequence: MDNLIEQYFAEIRKKNLSLNTIDAYRRDIKKFHEFLDEKGEKLREVDVITIMSYVQYLQKNGRANSSIVRNIVSIRNFFKYLEIKGIMDDNPVTQYEMPKIRRNFPDILTIEEVEKLLMGPDGNTDKGIRDKAMLEIMYATGMKVTELLNLTIYDINLKLSYIKCRGIKNKERIIPMGSYAVKCLEIYLKVRTKLNVQNIDYLFFNLQGDKMTRQGFWKIIKQYAQESGIKKKINAYTLRHSFAVHLLQNGADIKTIQELLGHSDMATTQIYSGMYRKTRIAEVYKKTHPRA
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.
What are the official names of this protein?
Putative tyrosine recombinase CA_C2066.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_THET2
Sequence: MDIREILKVLPHRYPFLLVDRVLEADERRFKALKNVTFNEPHFQGHFPGHPVMPGVLILEAMAQAAVGALVRQPGFPQGGLAFLAGVEGARFRRPVYPGDTLILEGELLAFRRGVGKVAVRALVEGEERASATLTFVLQGAS
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALMT1_ARATH
Sequence: MEKVREIVREGIRVGNEDPRRIIHAFKVGLALVLVSSFYYYQPFGPFTDYFGINAMWAVMTVVVVFEFSVGATLGKGLNRGVATLVAGGLGIGAHQLARLSGATVEPILLVMLVFVQAALSTFVRFFPWVKTKFDYGILIFILTFALISLSGFRDEEIMDLAESRLSTVVIGGVSCILISIFVCPVWAGQDLHSLLASNFDTLSHFLQDFGDEYFEAREKGDYKVVEKRKKNLERYKSVLDSKSDEEALANYAEWEPPHGQFRFRHPWKQYVAVGALLRQCAYRIDALNSYINSDFQIPVDIKKKLETPLRRMSSESGNSMKEMSISLKQMIKSSSSDIHVSNSQAACKSLSTLLKSGILNDVEPLQMISLMTTVSMLIDIVNLTEKISESVHELASAARFKNKMRPTVLYEKSDSGSIGRAMPIDSHEDHHVVTVLHDVDNDRSNNVDDSRGGSSQDSCHHVAIKIVDDNSNHEKHEDGEIHVHTLSNGHLQ
What is the function of this protein?
Malate transporter critical for aluminum tolerance.  The STOP1 transcription factor is required for ALMT1 expression.
What are the official names of this protein?
Aluminum-activated malate transporter 1, AtALMT1.
What is the protein family that this protein belongs to?
Belongs to the aromatic acid exporter (TC 2.A.85) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYC_SAMCY
Sequence: MGVPAGNAENGKKIFVQRCAQCHTVEAGGKHKVGPNLHGFYGRKTGQAPGFSYSNANKAKGITWGDDTLFEYLENPKKYIPGTKMVFAGLKKANERADLIAYLKESTK
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: MURG_SHIFL
Sequence: MSGQGKRLMVMAGGTGGHVFPGLAVAHYLMAQGWQVRWLGTADRMEADLVPKHGIEIDFIRISGLRGKGIKALIAAPLRIFNAWRQARAIMKAYKPDVVLGMGGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNAEVVGNPVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVAAKLGDSVTIWHQSGKGSQQSVEQAYAEAGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPALFVPFQHKDRQQYWNALPLEKAGAAKIIEQPQLSVDAVANTLAGWSRETLLTMAERARAASIPDATERVANEVSRAARA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LSPA_LISMO
Sequence: MYYYLITLAVIALDQLTKWIVVQNMEIGQKIEVIPGFLYWTSYRNDGAAWSILEGHMWFFYLITVVVIGIIIYIMQKYAKGKRLFSISLAFILGGAIGNFIDRVLHQEVVDFVQTVWGNYYFPIFNVADASLSVGVVLMLVYVFVDDRKTKGIK
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SENX3_MYCTO
Sequence: MTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMPLGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATGRSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR
What is the function of this protein?
Member of the two-component regulatory system SenX3/RegX3 involved in stress response (PubMed:19686042, PubMed:24722908).  Autophosphorylates, and then transfers the phosphate group to RegX3 (By similarity).  The system is involved in phosphate starvation response (PubMed:19686042).  Involved in virulence (PubMed:25344463).  SenX3 and RegX3 are equally required for optimal growth and morphological response during phosphate depletion (PubMed:25344463).
What are the official names of this protein?
Sensor-like histidine kinase SenX3.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SIR2_LEIMA
Sequence: MTGSPRAPHQEHALGEPTVEGLARYIREKDVRRILVLVGAGASVAAGIPDFRSSDTGIYAKLGKYNLDDPTDAFSLTLLREKPEIFYSIARELNLWPGHFQPTAVHHFIRLLQDEGRLLRCCTQNIDGLEKAAGVSPELLVEAHGSFAAAACIECHTPFSIEQNYLEAMSGTVSRCSTCGGIVKPNVVFFGENLPDAFFDALHHDAPIAELVIIIGTSMQVHPFALLPCVVPKSIPRVLMNRERVGGLLFRFPDDPLDTIHDDAVAKEGRSSSSQSRSPSASARREEGGTEDGSSSPNEEVEDASTSSSSDGYGQYGDYYAHPDVCRDVFFRGDCQENVLKLAECLGLREALAKRMRFSGAAPATARKTSNET
What is the function of this protein?
NAD-dependent deacetylase, which probably acts as a regulator of gene expression believed to help form modified chromatin structures on the genes it regulates.
What are the official names of this protein?
NAD-dependent protein deacetylase SIR2rp1, Regulatory protein SIR2 homolog 1, SIR2-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class I subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RHO2_YEAST
Sequence: MSEKAVRRKLVIIGDGACGKTSLLYVFTLGKFPEQYHPTVFENYVTDCRVDGIKVSLTLWDTAGQEEYERLRPFSYSKADIILIGFAVDNFESLINARTKWADEALRYCPDAPIVLVGLKKDLRQEAHFKENATDEMVPIEDAKQVARAIGAKKYMECSALTGEGVDDVFEVATRTSLLMKKEPGANCCIIL
What are the official names of this protein?
GTP-binding protein RHO2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: EUTL_ECOLI
Sequence: MPALDLIRPSVTAMRVIASVNADFARELKLPPHIRSLGLISADSDDVTYIAADEATKQAMVEVVYGRSLYAGAAHGPSPTAGEVLIMLGGPNPAEVRAGLDAMIAHIENGAAFQWANDAQDTAFLAHVVSRTGSYLSSTAGITLGDPMAYLVAPPLEATYGIDAALKSADVQLATYVPPPSETNYSAAFLTGSQAACKAACNAFTDAVLEIARNPIQRA
What is the function of this protein?
A component of the bacterial microcompartment (BMC) shell dedicated to ethanolamine degradation (Probable).  Two crystal forms have been seen; a form with a closed central pore that has 3 very small (1. 1-2. 2 Angstroms) channels per trimer lined by acidic and aromatic residues (PubMed:19451619, PubMed:20044574).  A form with a large central pore (8-12 Angstroms) has also been seen; this is probably a functional pore which allows molecules to enter and exit the BMC in a selective, gated manner (PubMed:20851901, PubMed:20044574).  Another group only sees the central pore in the presence of Zn(2+); soaking crystals in ZnCl(2) leads to dramatic conformational changes that open a central pore of about 12 Angstroms.  Whether Zn(2+) binding is physiologically relevant is unclear, however it suggests a gating mechanism exists (PubMed:20851901).  Ethanolamine-binding by the small channels has been hypothesized to stabilize the EutL central pore in a closed (non-transporting) state.  An open pore is thought to be large enough to transport ATP and/or cobalamin (By similarity).
What are the official names of this protein?
Bacterial microcompartment shell protein EutL, BMC-T, Ethanolamine utilization protein EutL.
What is the protein family that this protein belongs to?
Belongs to the EutL/PduB family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: HPRK_NITEU
Sequence: MSQVSITQLFEENQEKLNLQWGEPSAVIDRQLENHQINNSTQELIGHLNFVHPNWIQVLNQTSVNYLDQLDDVSLKKRLNQLAKSQLACLIVADDAPIPNAIRQFVNEQSVPLIQSATASLEIIWRLQSYLARMLAPAITRHGVLLDVLGMGVMITGESGVGKSELALELISRGHGLVADDVVELHRIGPETLEGQCPPLLRDFLEVRGLGMLNIRTIFGETAVRRRKNMKLIVHLEKTVGSSINAYERLPLSNLNEIILNVGIRKVIIPVAAGRNLAVLVEAAVRNYILQLRGIDSTQEFIRRHESEMAGNTAEHFDDSHNE
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: CASP1_CYNCS
Sequence: MEADSTTINVTETPKERKGKAPLLAAPPASSGVKRVLQKAPKGGYKRGLAVFDVVLRLAGIATALGAAIAMGSTDQTLPFFTQFFQFKAEFDDLPAFTFFVIANAITAAYLALTIPISIVCIIRPHLVAPRVLLIFLDTVMVALTTAAAGGTASIVYLAHNGNSDANWPAICQQFNDXCQKVSGAVVASFLTVVVLMLLIVLSAFAL
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 1, CsCASP1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: RRF_PSECP
Sequence: MIEETLLEAEEKMDKAVEVAKEDFASIRTGRANPGLYNRVLVDYYGSPTPLQQLASFAIPDARTILITPFDKTALRDIERALSDSEVGANPSNDGNVIRITIPELTKERRKEYVKIVKTKGEDAKVSIRNIRRKAKEALDRLVKDGEAGEDEGTRAEKELDGLTKAHVDGIDELLKRKEAELLEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAA2_CAMJE
Sequence: MQMIKKMVLSETFPGILLIFFTFLALLCKNSSLSVIYTDFFHANFTVGFDHFQISKSLDLWINDGLIAIFFLCIGLELKYEILRGQLKNIRAVSLPIFGALGGMITPALIFIAINYSHDFAMKGWAIPTATDIAFAVGILMLLGNKIPTSLKLFLLSLAIFDDLGAIVIIALFYTDQLSALAIIICLFCIFALLLLNYYHITHLSLYVLVGVVLWIAMLKSGVHATLAGVIISLFIPLDTKNKKPYLHEVLKDLNPWVVYFILPLFAFANAGIDIRDMHLGSVFSPVSLGIILGLFLGKQLGVFTFCFIAIKLKLAKLPENIKYGKFYGICILTGIGFTMSLFIDGLAYKNSDIFEYADKLAILVASFLSAIVGFIYLKIVK
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 2, Sodium/proton antiporter NhaA 2.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL6_POLSJ
Sequence: MSRVGKMPVTLPQGVDVAIKDDQINVKGALGALALTQNALVTIKNDAGKLTFAPANDSREANAMSGTMRQLVNNMVTGVTKGFEKKLSLIGVGYKAQAQGAKLNLTVGYSHPVIMDMPAGITVATPTPTEVVIKGSDRQRVGQIAAEVRAVRPPEPYKGKGIRYADEKITIKETKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: DS22B_DANRE
Sequence: MGNGINKVLPDLYLGNFKDARDREQLARNNITHILSIHDTAAPILQEMTYLCIAAADSPTQNLIQHFRQSIAFIHQSRLKGEGCLVHCLAGVSRSVTLVVAYIMTVTTLGWQEALAAVKIARPCASPNTGFQNQLQEFQTGELQQFREWLKEEYKENPFNDEEDIRNLLTKASTEEDAELQNN
What is the function of this protein?
Activates the Jnk signaling pathway.  Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) (By similarity).
What are the official names of this protein?
Dual specificity protein phosphatase 22-B.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NUOH_HELPY
Sequence: MSAYIIETLIKILILVAVFSALGGFATYIERKVLAYFQRRLGPCYVGPFGLLQVAADGIKLFTKEDIIPQGANKFIFTLAPIIAMVSAFVSMAPIPFFPNFTLFGYEIKPLISDINIGFLFFLAVGSAGIYAPILAGLASNNKYSLIGSARATIQLLSFEVVSTLTILAPLMVVGSLSLVEINHYQSGGFLDWLVFKQPLAFVLFLIASYAELNRTPFDLLEHEAEIVAGYCTEYSGLKWGMFFLAEYAHLFAFSFVISIVFFGGFNAWGFIPGGIAILIKAGFFVFLSMWVRATYPHVRPDQLMDMCWKIMLPLALLNIVLTGIIILI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OBG_PROA2
Sequence: MKFVDSARIVVKAGDGGNGCVSFRREKYVPKGGPDGGDGGRGGHVYLRANSQLATLLDFRYKKNYEALRGVHGQGSKKAGKTGKDIVINVPCGTLVKNSVSGEVICDLVEDGEEFLLARGGDGGRGNPHFTTSTRQAPRYAEPGGKGEELKVDLELKLMADVGLVGFPNAGKSTLISVLSAARPKIADYPFTTLVPNLGIVQYGEYKSFVMADIPGIIEGAAEGKGLGIQFLRHIERTKVLAVLVSGDGEDPVGEYRLLLGEMERFDPALLQKPRIIVVTKMDVVDEAFSLPDFEDDVPLIPVSSITRSGLEELRNALWNTINPSIP
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METN_ERWPE
Sequence: MVFYTIGPQTPQIDKGQIYGIIGYSGAGKSTLIRLLNGLEKPGSGSVTIAGQDIAQASVEALRQARLKISMVFQHFNLLWSRTVSENIAFSLQISGTSKSVIQDRVQELIALVGLVGKEQAYPSQLSGGQKQRVGIARALANNPNVLLCDEATSALDPQTTDAILELLLDINRKLWLTIVLITHEMHVVRKICHRVAVMEEGRIVEEGEVLSLFTHPQQPITRQFVKQTSGYISANVPFNPQLVNIDNGKVLKLTFVGQSTQQPVIGELTLKYGLAFNMLHGIMTQTTNGTFGEIWLQVPASQSQLPRILADLHAYEISTEVVTNV
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RNP1_METTH
Sequence: MITPRNIFRHELIGLSVRIARSVHRDIQGISGRVVDETRNTLRIEMDDGREITVPKGIAVFHFRTPQGELVEIDGRALVARPEERIKKKFRKP
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 1, RNase P component 1, Rpp29.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASGR1_RAT
Sequence: MTKDYQDFQHLDNENDHHQLQRGPPPAPRLLQRLCSGFRLFLLSLGLSILLLVVVCVITSQNSQLREDLRVLRQNFSNFTVSTEDQVKALTTQGERVGRKMKLVESQLEKHQEDLREDHSRLLLHVKQLVSDVRSLSCQMAALRGNGSERICCPINWVEYEGSCYWFSSSVKPWTEADKYCQLENAHLVVVTSWEEQRFVQQHMGPLNTWIGLTDQNGPWKWVDGTDYETGFKNWRPGQPDDWYGHGLGGGEDCAHFTTDGHWNDDVCRRPYRWVCETELGKAN
What is the function of this protein?
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed.  The receptor recognizes terminal galactose and N-acetylgalactosamine units.  After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated.  The receptor then returns to the cell membrane surface.
What are the official names of this protein?
Asialoglycoprotein receptor 1, ASGP-R 1, ASGPR 1, Hepatic lectin 1, HL-1, rHL-1.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.