PharMolix/UniProtQA huggingface dataset:
Protein: RUTB_STUS1
Sequence: MNAVEQISGYGLSATDEPVQLPARPEPLAMKASETALIVVDMQNAYASRGGYLDLAGFDVSATQPVIAKIRQALNAARAAGMQVIFLQNGWDNGYVEAGGPGSPNWHKSNALKTMRKRPELAGTLLAKGGWDYALVDELAPQPGDILVPKPRYSGFFNSQLDSTLRARGIRNLVFTGIATNVCVESTLRDGFHLEYFGVVLADATHQAGPEFAQQAALYNIETFFGWVSSVDAFCQSFAAAPEVAVAS
What is the function of this protein?
Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate.  The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.
What are the official names of this protein?
Ureidoacrylate amidohydrolase RutB.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family. RutB subfamily.
Protein: GCSH_CHLP8
Sequence: MNIPDNLRYTKDHEWLQLLDDGVTAVVGITDFAQSELGDIVFVETKPVGTKVAAHGAFGTVEAVKTVADLFAPVAGEIVEVNGALDDAAIVNSDPYNEGWIVKMKLDNAAEVESLLSPADYSALIGE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: ORF9B_SARS
Sequence: MDPNQTNVVPPALHLVDPQIQLTITRMEDAMGQGQNSADPKVYPIILRLGSQLSLSMARRNLDSLEARAFQSTPIVVQMTKLATTEELPDEFVVVTAK
What is the function of this protein?
Plays a role in the inhibition of host innate immune response by targeting the mitochondrial-associated adapter MAVS.  Mechanistically, usurps the E3 ligase ITCH to trigger the degradation of MAVS, TRAF3, and TRAF6.  In addition, causes mitochondrial elongation by triggering ubiquitination and proteasomal degradation of dynamin-like protein 1/DNM1L.
What are the official names of this protein?
ORF9b protein, Accessory protein 9b, ORF-9b, Protein 9b.
What is the protein family that this protein belongs to?
Belongs to the coronavirus group 2 protein 9b family.
What are the subcellular locations of this protein?
Virion. Host cytoplasmic vesicle membrane; Peripheral membrane protein. Host cytoplasm. Host endoplasmic reticulum. Host nucleus. Host mitochondrion. Note=Binds non-covalently to intracellular lipid bilayers.
Protein: PROA_METRJ
Sequence: MPVLNLRSDFAEADALPEQMGAIGRRARAAARRMALASARTKDAALKLIAERIRASRDEILSENARDVAAARCAGQTAALIDRLTLDPGRLAAIADAVEKVGSLADPVGRQLAAIERPNGLLIERIAVPLGVVGVIFEARPNVTADAGALCLKAGNAAILRAGSDSHRSAMAIARAMSRGLADAGLPEDAIQLVPTRDRAAVGLMLAGLDGCVDVIVPRGGRGLVERVQAEARVPVFAHLDGINHVYVAAAADLDMARTVLLNSKMRRTSVCGAAETLLVDRACAATHLAPLVQALLDAGCAVRGDAATRAVDPRVTAASEEDWHTEYLDAIIAVRVVDGIEAAIEHIETYGSHHTDAIITENDAEATRFLAEVDSAIVTHNASTQFADGGEFGFGAEIGIATGRMHARGPVGVEQLTTFKYRVHGTGQIRP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSPA_BEII9
Sequence: MRYLPLTPEDRTEMLARVGVPSVDALFEDIPAAKRLVELPDLPLHKGELEVERWLGRLSAKNLAASAAPFFVGAGAYKHHVPASVDHLIQRSEFMTSYTPYQPEIAQGTLQYVFEFQTQVAALTGMEVANASMYDGSTATGEAVLMAHRLTKRGKAILSGGLHPHYAQVVTSQAALTGHDVVVMPPDLQAKEDLVGRLDAQTSCLVVQSPDVFGNLRDLEPLAEACRKQGVLLIAVFTEAVSLGLVKAPGDMGADIVVGEGQSIGNALNFGGPYVGLFATRSKYLRQMPGRLCGETLDADGRRGFVLTLSTREQHIRRDKATSNICTNSGLCCLAFTIHLTLLGEQGLRQLATINHAHAVDLADRLAKVPGVELLNETFFNEFTIRLPGRAEDHVEALAAQGILAGVPVSRLLPGQGCDDLLIIASTEVNSDDDRAALVDALAKQIA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: ACTHR_PAPHA
Sequence: VLPEEIFFTISIVGVLENLIVLLAVFKNKNLQAPMYFFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFETTADDIIDSLFVLSLLGAIFSLSVIAADRYITIFHALRYHSIVTMRRTVVV
What is the function of this protein?
Receptor for corticotropin (ACTH).  This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase (cAMP).
What are the official names of this protein?
Adrenocorticotropic hormone receptor, ACTH receptor, ACTH-R, Adrenocorticotropin receptor, Melanocortin receptor 2, MC2-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS14Z_PSELT
Sequence: MPRKGIIERWKRPKKFKVREYTRCSVCGRPKAVYREFGLCRVCFRKMALEGKLPGVKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: GCSH_VESOH
Sequence: MSEIRDDRQYTQTHEWILDNGDDTYTMGITDHAQALLGDMVFVELPNVDDEVSIDDEFCVVESVKAASGVYSPADLQIIEANEALDDEPELVNSSCYDDGWLVKFKSHSVVDLMDSTAYAQILN
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: DDL_PARXL
Sequence: MSSIDPKQFGKVAVLLGGNSAEREVSLNSGRLVLQGLRDAGIDAHPFDPAERPLAALKEEGFVRAFNALHGGYGENGQIQGALDFYGIRYTGSGVLGSALGLDKFRTKLVWQQLGIPTPPFEAVLRGDDYEARAKEIVAKLGLPLFVKPASEGSSVAVIKVKSADALPAALIEAVKFDRIVVVEKSIEGGGEYTACIAGNLDLPVIRIVPAGEFYDYHAKYIANDTQYLIPCGLTADEEARLKVLARRAFDVLGCTDWGRADFMLDADGNPYFLEVNTAPGMTDHSLPPKAARAVGISYQELVVAVLALTLKD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_RHIEC
Sequence: MRIGLFAVGRLKSGPEKDLVARYLDRFAKAGSAVGLEFTRVAEVGESRASNAETRKREEAAMLLKSLAEGSVLILLDERGKALDSEAFAKLLGGYRDQGKRELTIAIGGADGLDPSLYDRADATLCLGKMTWPHQLVRTLIAEQLYRAVTILSGHPYHRV
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_RHOPS
Sequence: MTDAPVISPIDQARILSEALPHMQRYDEETIVIKYGGHAMGAENDAKAFARDIVLLEQTAVNPVVVHGGGPQIATMLKRLGIKSEFAAGLRITDGATIEIVEMVLAGSINKQLVGYINEAGGKAVGLCGKDGNMVTASKATRTMVDPDSRIEEVVDLGFVGEPEKVDLTLLNQLIGHELIPVLAPLATSATGQTFNVNADTFAGAVAGALKAKRLLLLTDVPGVLDKSKQLIPELSIKDARKLIADGTISGGMIPKVETCIYALEQGVEGVVILDGKVPHAVLLELFTNQGTGTLIHK
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNY_STRPI
Sequence: MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQEATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELKQIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAELERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRIAGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFDPIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHPDLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAIDHEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGARSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKVRKKIENNLDYPGNIKVTVIRELRAVDYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CH10_PSEPG
Sequence: MKLRPLHDRVVIRRSEEESKTAGGIVLPGSAAEKPNRGEVVAVGTGRILENGEVRALAVKVGDKVVFGPYSGSNTVKVDGEDLLVMAENEILAVIEG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACKA_MYCSJ
Sequence: MTRTVLVLNSGSSSLKFQLLEPDSGASLADGIVERIGEDSSSASLVCGEREVTHSERVPDHEAALRTAYGLFDEAGAELGSVGLVAVGHRVVHGGPDLYQPTLIDDALVDTLESLAPLAPLHNPPAVLGIRGARKAFPDLPHVAVFDTAYFHDLPAAAATYAIDRDLSEQWHIRRYGFHGTSHQYVSEQAALFLDVPLSSLSQIVLHLGNGASASAILGGRPIDTSMGLTPMEGLVMGTRSGDVDPGVLVYLWRTAGMSVDEIETMLNKRSGVRGLGGEIDFRVLHQRIESGDESDRENAQLAYDVYIHRLRKYIGAYLALLGSTDVIVFTAGVGENDAAVRRDALSGMGRLGIELDEHLNESPSHTARRISAETSPTTVLVIPTNEELAIARACVEVI
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHSE_LACLA
Sequence: MKIIVPATSANLGAGFDSIGIAVNLYLTVEVLEESNDWKIDHDLGNNIPTDEKNLLLTTLSAVLKAKNSSLSAKYHLKMTSEVPLARGLGSSSSVIIAGIELANQLAKLNLTTEEKLELACEIEGHPDNVAPALLGNLVIASTVADKTNYVSSDFPSCKLLAFVPDYELKTVESRKVLPKELAYKEAVAASSIANVLTASLLTKNLKVAGQMIESDHFHENYRASLVPELKILREIGHEFGAYGTYLSGAGPTVMLLLPDDKLNLLTEKINEQNLSGQLYSLEVDSNGLQVKESVL
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTP_BACC0
Sequence: MLLQGTHRIGRMAMLLALADQNESPVLSIPKGWKYCTGKVGSMNSQKVVAAMETAAKSNQVIETDVYRETHALYHAIMEALYGVTRGQIQLADVLRTVGLRFAIVRGTPYDGKKEGEWVAVALYGTIGAPVKGSEHEAIGLGINHI
What is the function of this protein?
Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
What are the official names of this protein?
Hut operon positive regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the HutP family.
Protein: CLPS_NEIG1
Sequence: MGHAMTAQHQSDTLLHRLNTLPPKRYGVFLLNDDYTTMEFVVEILTEIFMLGQEQAVAVMLSVHHEGKGLCGTYTRDIAQTKQQQVMQRAKAEGHPLQCIVEEI
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: RLMF_SHIFL
Sequence: MSAQKPGLHPRNRHHSRYDLATLCQVNPELRQFLTLTPAGEQSVDFANPLAVKALNKALLAHFYAVANWDIPDGFLCPPVPGRADYIHHLADLLAEASGTIPANASILDIGVGANCIYPLIGVHEYGWRFTGSETSSQALSSAQAIISANPGLNRAIRLRRQKESGAIFNGIIHKNEQYDATLCNPPFHDSAAAARAGSERKRRNLGLNKDDALNFGGQQQELWCEGGEVNFIKKMIEESKGFAKQVMWFTSLVSRGENLPPLYRALTDVGAVKVVKKEMAQGQKQSRFIAWTFMNDEQRRRFVNRQR
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_SYMTH
Sequence: MGLEEQLRLLPDRPGCYLFKDASGRIIYVGKARNLKNRVRQYFQSSRNLTAKVLAMVGQIVEIEHIVTDTETEALVLESNLIKKHKPKYNIRLRDDKHYPYLRLTLTEQWPRLVVARSMKKDGSRYFGPYTSSQAMWETMKLARRLFPLRTCNDPSRYPRGCLQYHIGRCLGPCLPDFDRHREYAEAVRDLQAFLEGRTQEVLERLRARMEQAAERLEFERAAELRDQIRAIEKVTEKQKIIAHTMVDLDVIAYARLYDEAGVQVFFVRQGKLVGRDQFLMSGADEMTGGEILAAFIQQHYSQTDFVPKEILVSEDLPDADVIAEWLSAKRGSRVALRCPKRGEKRALVEMVAQNAQEAMTERRQQRELELAATEGVLRELQAYLDLPRLPHRIECFDVSHVQGAEVVASMVVFEGGRPKKSDYRRFKMKVDQNNDFANMAEAVGRRFRRGLAERAAQVEGRVRDLEEGRVAEGGAEYGGKFADFPDLLIIDGGKGQLSYARAVMRELGVDHIPTFGLAKENELLCTEDRPDWIELPRGSQALFLLQRIRDEAHRFAITYHRKLHRRASTHSRLDDVPGIGPKRKKALLQHFGSLKAIREASVEEVAQVPGITLELAERVKEALGGPMR
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYW1_ORYSJ
Sequence: MPPPFPTATAAASTTSHLALLLLLSSSSVFFLYKSLRLRRNNPPSPPPGQGPAPTPTLLYASATGTSKALAAGLSRRLAEAGVTAHPADAAAFDPDDLPSLPLLLLVLPTHDGGAPPPAAAFLARWLEESAADFRAGAALLSGLRFAVFGVGSRAYGETFNAAARSFSRWLRALGAAEVVAVGEGDVDGGDLEVVFEEWCGRVVRVVKGEEIGEGHNGESDGFDELEEEESDDDDDEEEVDGGEVDMEDIAGKAPAARRRNGKVEGALSNGGENGVRDMVTPIIRTSLEKQGYKIIGSHSGVKICRWTKSQLRGRGGCYKHSFYGIESHRCMEATPSLACANKCVFCWRHHTNPVGKSWKWKMDDPLDIVNAAIDQHTKMVKQMKGVPGVKPERLAEGLSPRHCALSLVGEPIMYPEINVLIDELHRRHISTFLVTNAQFPDKIKTLKPITQLYVSVDAATKESLKAVDRPLFSDFWERFLDSLKSLHDKDQRTVYRLTLVKGWNAEEIDGYAKLLSLGQPDFIEIKGVTYCGSSATSKLTMENVPWHSDVKDFSEALALKSGGVYEVACEHAHSCCVLLAKVDKFKINGKWHTWIDYDRFHELVTSGKPFRSQDYMALTPSWAVYGAEEGGFDPDQSRYKKERRHGAAALKD
What is the function of this protein?
Probable component of the wybutosine biosynthesis pathway.  Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.  Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis (By similarity).
What are the official names of this protein?
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, tRNA wybutosine-synthesizing protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the TYW1 family.
Protein: HIS4_ERWT9
Sequence: MIIPALDLIDGNVVRLHQGDYGQQRDYGSDALPRLQDYQDQGAEVLHLVDLTGAKNPAARQTPLLSRLLAGVNVPVQVGGGIRHQDDVDALLQAGATRVVVGSTAVKQPEDVQQWFRQYGADAIVLALDVRIDADNRKEVAIGGWQEAAGMTLEQAIEQFLPYGLKHVLCTDISRDGTLAGSNVDLYREVSARYPQIAFQSSGGIGSLQDIRALRGSGAQGVIVGRALLENKFTVSEAISCWQNG
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_GRAFK
Sequence: MLYYLFKFLEEQYQLPGAQLFDFLSFRSAMAIILSLGISTIYGKRIINYLRAKQIGESVRDLGLKGQTEKAGTPTMGGVIIIIATLIPVLLFAKLENIYVILLIVTTLWMGAIGFLDDYIKTFKKDKEGLKGIFKVIGQIGLGLIVGCTMYFHPQITTKEVVTETNPTENVIARAEVVDMGPEVKDTTTTIPFVKNNEFEYSSLISWINPSLVNYAWLIFIPIVIFIVTAVSNGANLTDGIDGLAAGSSAIIVLTLGLFAWVSGNIIFSDYLNIMYIPRSGEMTIFITAFAGALVGFLWYNTYPAQVFMGDTGSLTIGGIIAVLAIATRKELLIPVLCGIFLIENLSVVMQVGWFKFTRMKYGEGRRIFLMSPLHHHYQKKGKHESKIVVRFWIIGIFLAILSIITLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DSBD_TATCI
Sequence: MVARLTRLIILALTLFSLHAQAGLFDSGSSPHFVTVNQAFGFDFSQNNHNVVLRWKVKPGYYLYRQQFSITGTNAVIAGIALPSGQPHEDEFFGKSQIFPQDVQIPVTLKSTLPGATLKISYQGCAAAGFCYPPETREVPLSQVSTTRSEAPATAAATPAPVPEPQSGPAVSRLPFSPLWALLIGIGIAFTPCVLPMYPLISAIILGGRRDVRASRILLLAFVYVQGMGLTYTLMGIVVAAAGLRFQAALQSPVILLSLSAVFILLALSMFGLFSLQLPSSLQTRLTLWSNRQQGGSLSGVFLMGALAGLICSPCTTAPLSAILLYIAQSGNMLAGGGTLYLYALGMGLPLIIVTLFGNKLLPKSGPWMQSVKEGFGFVILALPVFLIDRVAGDLWGMRLWSLLGVAFFGWAFALSLKSPKGWMRVLQIVWLLAALVAARPLQDWAFATPGVTASQEQALPFQNIGTVADLQQQLSQAQGKITMVDLYADWCVACKEFEKYTFTDPQVRQEFSQFRLVQANVTANSAQDNALLTHLNVLGLPTLLFFDANGHEIPDSRVTGYMNASQFLAHLRKLRAE
What is the function of this protein?
Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes.  Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm.  This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity).
What are the official names of this protein?
Thiol:disulfide interchange protein DsbD, Protein-disulfide reductase, Disulfide reductase.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MMDB_PROMO
Sequence: MLQAILDFYHSTGFYGLNMGSIIMMLVACVFLYLAIAKEFEPLLLVPISFGILLTNLPFAGMMAEPLLEVHEKLSASGAHLYTAHTAEPGGLLYYLFQGDHLGIFPPLIFLGVGAMTDFGPLISNPKSLLLGAAAQFGIFVTFFGAIASGLFTAQEAASIGIIGGADGPTAIFLSSKLAPHLMGPIAVAAYSYMALVPIIQPPIMTALTSETERKIKMSQLRLVSKREKIIFPIVVTILVSLIVPPAATLVGMLMLGNLFRECGVVGRLEDTAKNALINIITIFLGVTVGATATAEAFLKVETLAILGLGIVAFGIGTGSGVLLAKFMNKLSKEPINPLLGSAGVSAVPMAARVSQVVGQKADPTNFLLMHAMGPNVAGVIGSAVSAGVLLSLFG
What is the function of this protein?
Tunnel subunit of the sodium ion pump methylmalonyl-CoA decarboxylase, which converts the chemical energy of a decarboxylation reaction into an electrochemical gradient of Na(+) ions across the cytoplasmic membrane, thereby creating a sodium ion motive force that is used for ATP synthesis (PubMed:9428714).  The beta subunit catalyzes the decarboxylation of the carboxybiotin carrier protein and the coupled export of Na(+) ions (By similarity).
What are the official names of this protein?
Methylmalonyl-CoA decarboxylase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the GcdB/MmdB/OadB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROH_ECOL6
Sequence: MNRTDELRTARIESLVTPAELALRYPVTPGVATHVTDSRRRIEKILNGEDKRLLVIIGPCSIHDLTAAMEYATRLQSLRNQYQSRLEIVMRTYFEKPRTVVGWKGLISDPDLNGSYRVNHGLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGAIGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMTIYQTSGNPYGHIIMRGGKKPNYHADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRRQLEVCEDICQQIRNGSTAIAGIMAESFLREGTQKIVGGQPLTYGQSITDPCLGWEDTERLVEKLASAVDTRF
What is the function of this protein?
Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).
What are the official names of this protein?
Phospho-2-dehydro-3-deoxyheptonate aldolase, Trp-sensitive, 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, DAHP synthase, Phospho-2-keto-3-deoxyheptonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class-I DAHP synthase family.
Protein: CCA_ENT38
Sequence: MKIYLVGGAVRDALLGLPVKDKDWVVVGATPEEMLNAGYQQVGRDFPVFLHPKTREEYALARTERKAGLGYTGFTCYAAPDVTLEQDLLRRDLTINALAQDDEGHIIDAYGGKRDLQNRLLRHVSPAFSEDPLRVLRVARFAARYAHLSFRIADETLALMTAMTAAGELEHLTPERVWKETENALTTRNPQVFFQVLRDCGALKVLFPEIDALFGVPAPAKWHPEIDTGIHTLMTLSMAAMLSPEVDVRFATLCHDLGKGLTPKEFWPRHHGHGPAGVKLVEGICQRLRVPNDIRDLAKLVAEFHDLIHTFPILKPATIVKLFDNIDAWRKPQRVEQIALTSEADVRGRTGFEACDYSQGRLLREAWEIAKAVPTKDVVEAGFKGPEIREELTKRRVQAVADWKEKRCPQPKD
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: RUSD4_MOUSE
Sequence: MAAPCLRTPGVQLLSMSSRPGRLFTPGSWSFCSSATSSRPLNAQRLAEKLRAQKQEQKAKEVRVPTNPVQRRVQELVRFTQQLQRVHPNVLAKELSRRILHQDNDLVVINKPYGLPVHGGPGVQLCISDVLPILAKMLHGHKAEPLHLCHRLDKETTGVMVLAWEKDMAHQVQELFRTRQVEKKYWAITVRVPLPSAGVVDIPIKEKEVQGPQQHHKMTLSPSYRLDNGKMVKVRASRDAHVAVTQYQVLSSASSSALVELQPVTGIKHQLRVHLSFGLDCPILGDHKYSDWTRLAPQKLSAGTLKKLGLQQSKARYIPLHLHARQLILPALGSRTEELLLTCKLPHFFARSLLRLGLDMPNQDQSRGNKARHVEAR
What is the function of this protein?
Catalyzes uridine to pseudouridine isomerization (pseudouridylation) of different mitochondrial RNA substrates.  Acts on position 1397 in 16S mitochondrial ribosomal RNA (16S mt-rRNA).  This modification is required for the assembly of 16S mt-rRNA into a functional mitochondrial ribosome.  As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA, controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation.  Acts on position 39 in mitochondrial tRNA(Phe).  Also catalyzes pseudouridylation of mRNAs in nucleus: acts as a regulator of pre-mRNA splicing by mediating pseudouridylation of pre-mRNAs at locations associated with alternatively spliced regions.  Pseudouridylation of pre-mRNAs near splice sites directly regulates mRNA splicing and mRNA 3'-end processing.
What are the official names of this protein?
Pseudouridylate synthase RPUSD4, mitochondrial, RNA pseudouridylate synthase domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Mainly localizes to mitochondrion. Localizes to mitochondrial RNA granules, platforms for post-transcriptional RNA modification and ribosome assembly. Also found in nucleus and cytoplasm.