PharMolix/UniProtQA huggingface dataset:
Protein: NTPTH_PYRFU
Sequence: MKKFRFFVSGMPGVGKTTLAKRIADEIKREGFKVGGIITQEIRSGARRSGFRVIALDTGEIGRLAYVGQGYPRLGRYVIDVESFEKVAIPAISRALREGDLIVIDEIGPMEFKSNEFLKALGLVLRSEKPLLATVHRRFVERYRPLGEYYWLTPENREAVFSEILVKIKELLRENENAGNKAQD
What is the function of this protein?
Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP.  May hydrolyze nucleoside diphosphates with lower efficiency.
What are the official names of this protein?
Nucleoside-triphosphatase THEP1, NTPase THEP1, Nucleoside triphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the THEP1 NTPase family.
Protein: VGLG_BDV1
Sequence: MQLSMSFLIGFGTLVLALSARTFDLQGLSCNTDSTPGLIDLEIRRLCHTPTENVISCEVRYLNHTTINLPAVHTSCLKYHCKTYWGFFGSYSADRIINRYTGTVKGCLNNSAPEDPFECNWFYCCSAITTEICRCSITNVTVAVQTFPPFMYCSFADCSTVSQQELESGKAMLSDGSTLTYTPYILQSEVVNKTLNGTILCNSSSKIVSFDEFRRSYSLANGSYQSSSINVTCVNYTSSCRPRLKRRRRDTQQIEYLVHKLRPTLKDAWEDCEILQSLLLGVFGTGIASASQFLRGWLNHPDIIGYIVNGVGVVWQCHRVNVTFMAWNESTYYPPVDYNGRKYFLNDEGRLQTNTPEARPGLKRVMWFGRYFLGTVGSGVKPRRIRYNKTSHDYHLEEFEASLNMTPQTSIASGHETDPINHAYGTQADLLPYTRSSNITSTDTGSGWVHIGLPSFAFLNPLGWLRDLLAWAAWLGGVLYLISLCVSLPASFARRRRLGRWQE
What is the function of this protein?
Envelope protein p27 and p29 presumably linked by disulfide bond are the viral type II fusion protein, involved in pH-dependent fusion within early endosomes after internalization of the virion by endocytosis.
What are the official names of this protein?
Envelope glycoprotein p57, gp84, gp94.
What are the subcellular locations of this protein?
[Envelope glycoprotein p57]: Host endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Accumulates in the endoplasmic reticulum when unprocessed, whereas cleaved products reaches cell surface. SUBCELLULAR LOCATION: [Envelope glycoprotein p27]: Virion. Host cell membrane; Peripheral membrane protein. Note=Appear to be associated with infectious virions. SUBCELLULAR LOCATION: [Envelope glycoprotein p29]: Virion. Host cell membrane; Single-pass type I membrane protein. Note=Appear to be associated with infectious virions.
Protein: RL24_HELPS
Sequence: MKSEIKKNDMVKVIAGDDKGKVAKVLAVLPKTSQVVVEGCKVVKKAIKPTDDNPKGGFIHKEKPMHISNVKKA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: SYC_SHISS
Sequence: MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHKDFDALNILRPDMEPRATHHIAEIIELTEQLIAKGHAYAADNGDVMFDVPTDPTYGVLSRQDLDQLQAGARVDVVDDKRNPMDFVLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQSTCAHDGQYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLYTALRGTEKTVAPAGGEAFEARFIEAMDDDFNTPEAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLEDGPQGTTWRRK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_SHEHH
Sequence: MSESRIDFRKAEFLISAPDIAHLNEYLPGDVGVEIAFAGRSNAGKSSALNLLTEQKIARTSKTPGRTQLINVFKLDKHRRLVDLPGYGFAQVPLALKLKWQQALGEYLLKRDCLSGVVVLMDIRHPLKDLDMQMIEWAVESHIPVLALLTKADKLGQSDRMKMVNEVRKKLSNFDDAVKVEPFSSLKGIGKSKVLSILDGWCKPEWLMQQIEADAIAAAQAEAGKE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RK32_PELHO
Sequence: MTVPKKRLSSSKKRIRKNIWKGKGHWAALKALSLGKSLSTGNSKSFFRFFSMPTRFFSMPTDNKKTKKS
What are the official names of this protein?
50S ribosomal protein L32, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CHOD_STRS0
Sequence: MTAQQHLSRRRMLGMAAFGAAALAGGTTIAAPRAAAAAKSAADNGGYVPAVVIGTGYGAAVSALRLGEAGVQTLMLEMGQLWNQPGPDGNIFCGMLNPDKRSSWFKNRTEAPLGSFLWLDVVNRNIDPYAGVLDRVNYDQMSVYVGRGVGGGSLVNGGMAVEPKRSYFEEILPRVDSSEMYDRYFPRANSMLRVNHIDTKWFEDTEWYKFARVSREQAGKAGLGTVFVPNVYDFGYMQREAAGEVPKSALATEVIYGNNHGKQSLDKTYLAAALGTGKVTIQTLHQVKTIRQTKDGGYALTVEQKDTDGKLLATKEISCRYLFLGAGSLGSTELLVRARDTGTLPNLNSEVGAGWGPNGNIMTARANHMWNPTGAHQSSIPALGIDAWDNSDSSVFAEIAPMPAGLETWVSLYLAITKNPQRGTFVYDAATDRAKLNWTRDQNAPAVNAAKALFDRINKANGTIYRYDLFGTQLKAFADDFCYHPLGGCVLGKATDDYGRVAGYKNLYVTDGSLIPGSVGVNPFVTITALAERNVERIIKQDVTAS
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidation of the 3-beta-hydroxy group of cholesterol and the isomerization of the double bond of the resulting product, producing cholest-4-en-3-one.  These reactions are part of a cholesterol degradation pathway that allows the bacterium to utilize cholesterol as its sole source of carbon and energy.
What are the official names of this protein?
Cholesterol oxidase, CHOD, Cholesterol isomerase.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYB_MYOOX
Sequence: MTNIRKSHPLVKIINSSFIDLPAPSNISSWWNFGSLLGICLALQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWVLRYLHANGASMFFICLYLHVGRGLYYGSYMYTETWNIGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFLLPFIIAAMVMVHLLFLHETGSNNPTGIPANADMIPFHPYYTIKDILGLLLMITALLTLVLFFPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILIIVPLLHTSKQRSMTFRPLSQCLFWLLXADLFTLTWIGGXPVEHPYIIIGQLASILYFSIIXILMPLTSLVXXHLXXX
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PHR_METTH
Sequence: MIHAERIRNLNGEEPDLRGSYVVYWMQASVRSHWNHALEYAIETANSLKKPLIVVFGLTDDFPNANSRHYRFLIEGLRDVRSNLRERGIQLVVERDSPPSVLLKYADDAAAAVTDRGYLDIQKEWVDEAAGALHIPLTQVESNVIVPVETASDKEEYSAGTFKPKIKRHLKRFMVPLRMRTLKMDSLDLEPGPEFEDAVRDFRAPEDLEPSVFRGGTSTALSIFSEFLREKLECFERYRNDPVKNCLSNMSPYLHFGQISPLYLALRASEAGECPEFLEELIVRRELSMNFVHYSDSYSSISCLPEWAQRTLMDHVADPREYEYSLRELESASTHDPYWNAAQQEMVITGKMHGYMRMYWGKKILEWTDHPARAYDIALYLNDRYEIDGRDPNGFAGVAWCFGKHDRAWAEREIFGKVRYMNDRGLKRKFRIDEYVDRIRGLMDE
What is the function of this protein?
Involved in repair of UV radiation-induced DNA damage.  Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation.
What are the official names of this protein?
Deoxyribodipyrimidine photo-lyase, DNA photolyase, Photoreactivating enzyme.
What is the protein family that this protein belongs to?
Belongs to the DNA photolyase class-2 family.
Protein: PABP_EMENI
Sequence: MSAETSTTPAPAENTNGTPDNAPAPEVTAVEAPATTSQPHSASLYVGELDPSVTEAMLYELFSSIGQVASIRVCRDAVTRRSLGYAYVNYNDTAHGERALDELNYTLIKGKPCRIMWSQRDPALRKTGQGNVFIKNLDSAIDNKALHDTFAAFGNILSCKVAQDEFGVSKGYGFVHYETAEAANNAIKHVNGMLLNDKKVFVGHHISKKDRQSKFEEMKANFTNIYIKNIDPEVEDEEFRKLFEKFGEITSATLSRDSEGKSRGFGFVNFSTHESAQAAVEEMNDKEVRSQKLYVGRAQKKHEREEELRKQYEAARMEKASKYQGVNLYVKNLTDDVDDDKLRELFGPYGTITSAKVMRDTAPVETATPESETKESANKENEKAAEGEKEPAAEEKEKEEKKEAEQKPEKKPLGKSKGFGFVCFSSPDEASKAVTEMNQRMVNGKPLYVALAQRKDVRRSQLEASIQARNNIRQQQAAAAAGMGQAYMAPAVFYGPGQQGFIPGAQRGGMFPPQPGMMMGMPGRPGQYPGPFPGQQGGRGVGPNQQIPPNFQGLPMGAMQGPGIPNGMGYPMVQGQFGGGRGRGQVPGMGGPMRGGYGGGRGGVPLGGQMRPGQGGRGQAVGQPGPETPVGVLTAQALSAAPPQQQKQMLGEALYPKIQATQPELAGKITGMLLEMDNTELLGLLEDDEALRAKVDEALSVYDEYMKNKSDEPAAEKPKEAAQEAPAEENKA
What is the function of this protein?
Binds the poly(A) tail of mRNA.  Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation.  In the nucleus, involved in both mRNA cleavage and polyadenylation.  Is also required for efficient mRNA export to the cytoplasm.  Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation.  In the cytoplasm, stimulates translation initiation and regulates mRNA decay through translation termination-coupled poly(A) shortening, probably mediated by PAN (By similarity).
What are the official names of this protein?
Polyadenylate-binding protein, cytoplasmic and nuclear, PABP, Poly(A)-binding protein, Polyadenylate tail-binding protein.
What is the protein family that this protein belongs to?
Belongs to the polyadenylate-binding protein type-1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RBL_CATSP
Sequence: SVGFKAGVKDYKLNYYTPQYQTKDTDILAAFRVTPQPGVPPEERGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVVGEEDQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPTSYIKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTTLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHVHAGTVVGKLEGERDITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVIPVASGGIHVWHMPALTEIFGDDAVLQFGGGTLGHPWGNAPGAVANRVALEACVKARNEGRDLAVEGNEIIREASKWSPELAAACEVWKEIRFNFAAVDTLDP
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ALF_COCIM
Sequence: MPHPSLKSNRALPLLTFARTHSFAIPAICVYNLEGILAIIRAAEHKRSPAMILLFPWAIQYADSLLVRTAASACRAASVPITLHLDHAQDPEIIKRAADLSRSETHEPGFDSIMVDMSHFSKEENLRLTRELVAYCNARGIATEAEPGRIEGGEDGVQDTVDLEGVLTTPEESEEFVATGINWLAPAFGNVHGNYGPRGVQLDYERLQRINEAVGERVGLVLHGADPFTKEIFEKCIERGVAKVNVNRAVNNEYVKVMREKAGSLPITRLHEEVTNAMQAAVEKIMDMIDSTGKAEFMMDEK
What is the function of this protein?
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
What are the official names of this protein?
Putative fructose-bisphosphate aldolase, FBP aldolase, FBPA, Putative fructose-1,6-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family.
Protein: DNAK_AZOSB
Sequence: MGKIIGIDLGTTNSCVSVMEGGKPKVIENSEGARTTPSVVAYAEDGEILVGAPAKRQAVTNARNTLFAVKRLIGRRFEEKEVQKDIDLMPYTIAKADNGDAWVEVRGKKIAPPQVSAEVLRKMKKTAEDYLGEEVTEAVITVPAYFNDSQRQATKDAGRIAGLEVKRIINEPTAAALAFGMDKKPGDSKIAVYDLGGGTFDISIIEIADIDGEHQFEVLATNGDTFLGGEDFDQRIIDYIVTEFKKEQGVDLKNDVLALQRLKEAAEKAKIELSSGSQTEVNLPYITADATGPKHLAIKITRAKFESLVEDLIERSIEPCRIALKDAGVKVSDIDDVILVGGQTRMPKVIEKVKEFFGKEPRRDVNPDEAVAVGASIQGGVLQGEVKDVLLLDVTPLSLGIETLGGVMTKLIQKNTTIPTKASQVFSTADDNQSAVTIHVLQGEREMASGNKSLGQFNLSDIPPAPRGMPQIEVTFDIDANGILHVSAKDKATGKENKIKIQANSGLSDEEVERMVRDAAAHAEEDKKAHELVDARNQCDALIHSTKKALAEHGDKIGADDKAKIEAAMKDAEEAIKSGDKDSIEAKSQALAMASQKLGEAMYGQQQAEGGAQAAGAAGGSSKADDADVVDAEFTEVKDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: HCDS2_XANP2
Sequence: MARAAVRAGAKVALIDRDGACAEKAAAEIGAAAWGVGADVTDEAAIAAAMAGAERALGPLTGLVNNAGIAGFGSVHTTEVETWGRIMAVNVTGTFLASKAALSGMLERRRGAIVNFGSVAGLVGIPSMAAYCAAKGAVVSLTRQMAAEYSGQGIRVNVVCPGTVASTDMGRQLLGQDADPELEARRLAKYPIGRFGTPEDIAEAAIFLLSTKAAFVTGCVFAVDGGMTAI
What are the official names of this protein?
Inactive 2-(S)-hydroxypropyl-CoM dehydrogenase 2, SHPCDH2.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: HRCA_THEP1
Sequence: MRRLNRKNSDASKKLNDRQRKVLYCIVREYIENKKPVSSQRVLEVSNIEFSSATIRNDMKKLEYLGYIYQPHTSAGRIPTDKGLRFYYEEMLKISKETSEADLAVETFKSMPLADPEKVLFLAGNLLARLTEGYVLIERPNTRDLKILRVMLIPVSEDYLIFSILTEFGVSRVTPIKTQERLNWEEIERQLNFLLRGKTIGEVLLGRIESLKGSGFLRLIESLIGETIERYLDAGLENLLKDETLALEDIRNLLEEIKDQKFLESLVGEGISVMIGREIGRKNLEKFAVFSGRYFKGESPIGSVYFFTSKVTRYDRNHKIFEYILNRLSEYFTSTSRR
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: MUTL_GEOSL
Sequence: MPHRIRILPEILTNKIAAGEVVERPASVVKELVENALDAGCGEIIVEIEGGGRRLIRITDDGCGMSREDALMALERHATSKIATDDDLFSLATLGFRGEALPSVASVSRFTLATRERGSIEGTEIYAEGGKIREVKACGMAEGTVVSVRNLFFNTPARLKFMKSVETEGGHVADLVTRLALSRPEVRFTCVSDGKTLFRALDGTLLDRVAALLGKTVASALHPVDLATEGVRVTGLVARPDVSRSAASHLYTYINGRFIRDRVVQHAILQAYRNFLERGRYPVVVLFIEVSPGEVDVNVHPTKHEVRFRQQGIVHDVIQGAVEETLRLTPWIRRSESPVAAPLAVPRPQQYVQGTGARQVEEVRELLENYRPAVAPHRPLFAPQPAPQPDREPPLPDSGSRMLDDTAVRRHGGYFSSLAVIGQYNASYILCQDGSDLVIIDQHAAHERVAFERLKTQFAAGRVEGQGLLFPETVELSHRESAVVREHGGELGRLGFDLEDFGGTTWIVKGIPRLLAGTDYLRLLRDTLEELQSLGASRSIADAVEDILTRVACHSVVRGEHPLTTGEIEALFAHMDATDFSTNCPHGRPVLQRLTLGEVEKMFKRV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: PUR5_ECO5E
Sequence: MTDKTSLSYKDAGVDIDAGNALVGRIKGVVKKTRRPEVMGGLGGFGALCALPQKYREPVLVSGTDGVGTKLRLAMDLKRHDTIGIDLVAMCVNDLVVQGAEPLFFLDYYATGKLDVDTASAVISGIAEGCLQSGCSLVGGETAEMPGMYHGEDYDVAGFCVGVVEKSEIIDGSKVSDGDVLIALGSSGPHSNGYSLVRKILEVSGCDPQTTELDGKPLADHLLAPTRIYVKSVLELIEKVDVNAIAHLTGGGFWENIPRVLPDNTQAVIDESSWQWPEVFNWLQTAGNVERHEMYRTFNCGVGMIIALPAPEVDKALALLNANGENAWKIGIIKASDSEQRVVIE
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCNG1_RAT
Sequence: MIEVLTTDSQKLLHQLNTLLEQESRCQPKVCGLKLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQAKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLIRETLPFERRNDLNFERLEAQLKACHCRIIFSKAKPSVLALAIIALEIQALKYVELTEGVECIQKHSKISGRDLTFWQELVSKCLTEYSSNKCSKPNGQKLKWIVSGRTARQLKHSYYRITHLPTIPETMG
What is the function of this protein?
May play a role in growth regulation.  Is associated with G2/M phase arrest in response to DNA damage.  May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation.
What are the official names of this protein?
Cyclin-G1, Cyclin-G.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin G subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RK36_CERDE
Sequence: MKIRASVRKICEKCRLIRRRGRIIVICSNPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: C42_NPVOP
Sequence: MSVIDVHIRIDSLRRLIDENMQMEIWPQLLRMCSDTVSDVDVDTSALMAFLVTVARKSQTAFANANAATASAFAAGGARAPAAMPAPAPPAQTVFGALVSAPSAEPALVDMRRYRAAARRLIQYYSLNTTTSSEFKVRDVVMTMIFLQRSENYHQLFKLLDTAMDDFTCRPQLTEAQVSTLLHTLRTLLEMPTTPIDMTTVDVMRSSFARCFASPVLRYAKVVLLQGETVSRDERTTLEELLVERGDNIQKLQPQQYVASGSEIPFCDDPEFINRLLKHLDPYPLSRMYYNAANSMFYTTMENYAVANCKFNIEDYNRIFKGAESIKKHANKTAEDSDELDIYLGTTAKRKKII
What are the official names of this protein?
Protein C42, C42, ORF3, P40.
What is the protein family that this protein belongs to?
Belongs to the baculoviridae C42 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: SYS_GEOSW
Sequence: MLDVKYLRNHFEEVKEKLLKRGEDLTNIDRFEELDKKRRELIAKAEELKNKRNEVSQQIAVLKREKKDADHLIAEMRDVGDRIKTMDDEIRQVEEELNALLLSIPNIPHESVPVGKSEEDNVEVRKWGEPRSFSFEPKPHWDIAEQLGILDFERAAKVTGSRFVFYKGLGARLERALINFMLDVHIEEFGYQEILPPYLVNRASMTGTGQLPKFEEDAFRIETDDYFLIPTAEVPVTNLHRDEILSAEDLPIYYVAYSACFRAEAGSAGRDTRGLIRQHQFNKVELVKFVKPEDSYDELEKLTNQAERILQLLGLPYRVVCLCTGDLGFSSAKTYDIEVWLPSYGTYREISSCSNFEAFQARRANIRFRREPKAKPEYVHTLNGSGLAIGRTVAAILENYQQEDGTVVIPEVLRPYMGNLEVIR
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_BORBR
Sequence: MSGNTLGTLFCVTNFGESHGPAIGCVVDGCPPGLPLEAADIQAELDRRRPGTSRHVTQRQEADQVEILSGVYEGVTTGTPIGLLIRNTDARSKDYSNIADTFRPGHADFAYWRKYGVRDPRGGGRSSARLTAPTVAAGAIAKKWLAGQFGVRVRGYMSQLGPIAIPFSSWDDVPGNAFYAPNAAVVPELEAYMDQLRRDGDSVGARIEVVAEGLPAGWGEPIYDRLDADIAHAMMGLNAVKGVSLGAGFESIAQRGSEHGDEITPEGFASNHAGGVLGGISTGQPITVSLAIKPTSSIRVERRSVNRAGEPVMVQTLGRHDPCVGIRATPIAEALLALVLIDHALRQRAQCGG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RS12_MYCLE
Sequence: MPTIQQLVRKGRRDKIGKVKTAALKGNPQRRGVCTRVYTSTPKKPNSALRKVARVKLTSQVEVTAYIPGEGHNLQEHSMVLVRGGRVKDLPGVRYKIIRGSLDTQGVKNRKQARSRYGAKKEKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RPIA_POLAQ
Sequence: MNQDQLKKMVGDAARDEVLKLPAGQILGVGTGSTANCFIDALAPHKDHFAGTVSSSNATTERLLKHGFKVLDPNDVVSLPAYVDGADEIDPQGHMIKGGGGALTREKIIASMAQQFICICDSSKQVPVLGNFALPVEIIPLAKGVVTRELEKLGGKVTLRLAKSTRADLNQTPSEPFVTDNGGWILDIAGLQIADPLKIESQINQIAGVITVGLFAKEKANILLVSNAAGVDRIVL
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: COF_ECODH
Sequence: MARLAAFDMDGTLLMPDHHLGEKTLSTLARLRERDITLTFATGRHALEMQHILGALSLDAYLITGNGTRVHSLEGELLHRDDLPADVAELVLYQQWDTRASMHIFNDDGWFTGKEIPALLQAFVYSGFRYQIIDVKKMPLGSVTKICFCGDHDDLTRLQIQLYEALGERAHLCFSATDCLEVLPVGCNKGAALTVLTQHLGLSLRDCMAFGDAMNDREMLVSVGSGFIMGNAMPQLRAELPHLPVIGHCRNQAVSHYLTHWLDYPHLPYSPE
What is the function of this protein?
Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).
What are the official names of this protein?
HMP-PP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family.
Protein: Y2140_BRADU
Sequence: MYDRIGGSSTRTSQTDEPSQSVDSGSFTETLADLAPQWSSRSGELPDKMGACCSKPDTLDANVQTSSASEPSTSSPESPATSLFEYRTADLRDANVDGICVGLTAEWFRNLSNSPSTRMSALTPGSQTHASAAERQQQYQRLKDQLRSRGAGSSQADLQAQNTILEEAGLEPAGEEKRFAFGKSSNVKSMVNEINEDGSNHLLSLYFAEGGAHTVATSASNGTTTLFDPNYGEFTVRSDPDQMASLLQSLANRYRNPNGQHLSTITTQRMQ
What is the function of this protein?
Potential cysteine protease, which may play a central role after invasion of host cell.
What are the official names of this protein?
Putative cysteine protease YopT-like blr2140.
What is the protein family that this protein belongs to?
Belongs to the peptidase C58 family.
Protein: TAT_HV19N
Sequence: MDPVDPKLEPWNHPGSQPTTPCNKCYCKVCCWHCQVCFLNKGLGISYGRKKRRPRRGTPQGSKDHQNPVPKQPLPITSGNPTGSEKPKKEVASKTETDPLD
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors such as CD26, CXCR4, heparan sulfate proteoglycans (HSPG) or LDLR.  Neurons are rarely infected, but they internalize Tat via their LDLR.  Through its interaction with nuclear HATs, Tat is potentially able to control the acetylation-dependent cellular gene expression.  Modulates the expression of many cellular genes involved in cell survival, proliferation or in coding for cytokines or cytokine receptors.  Tat plays a role in T-cell and neurons apoptosis.  Tat induced neurotoxicity and apoptosis probably contribute to neuroAIDS.  Circulating Tat also acts as a chemokine-like and/or growth factor-like molecule that binds to specific receptors on the surface of the cells, affecting many cellular pathways.  In the vascular system, Tat binds to ITGAV/ITGB3 and ITGA5/ITGB1 integrins dimers at the surface of endothelial cells and competes with bFGF for heparin-binding sites, leading to an excess of soluble bFGF.
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Secreted. Note=Probably localizes to both nuclear and nucleolar compartments. Nuclear localization is mediated through the interaction of the nuclear localization signal with importin KPNB1. Secretion occurs through a Golgi-independent pathway. Tat is released from infected cells to the extracellular space where it remains associated to the cell membrane, or is secreted into the cerebrospinal fluid and sera. Extracellular Tat can be endocytosed by surrounding uninfected cells via binding to several receptors depending on the cell type.