PharMolix/UniProtQA huggingface dataset:
Protein: VP2_POVMA
Sequence: MGAALTILVDLIEGLAEVSTLTGLSAEAILSGEALAALDGEITALTLEGVMSSETALATMGISEEVYGFVSTVPVFVSRTAGAIWLMQTVQGASTISLGIQRYLHNEEVPTVNRNMALIPWRDPALLDIYFPGVNQFAHALNVVHDWGHGLLHSVGRYVWQMVVQETQHRLEGAVRELTVRQTHTFLDGLARLLENTRWVVSNAPQSAIDAINRGASSASSGYSSLSDYYRQLGLNPPQRRALFNRIEGSMGNGGPTPAAHIQDESGEVIKFYQAQVVSHQRVTPDWMLPLILGLYGDITPTWATVIEEDGPQKKKRRL
What is the function of this protein?
Structural protein that resides within the core of the capsid surrounded by 72 VP1 pentamers.  Following virus endocytosis and trafficking to the endoplasmic reticulum, VP2 and VP3 form oligomers and integrate into the endoplasmic reticulum membrane.  Heterooligomer VP2-VP3 may create a viroporin for transporting the viral genome across the endoplasmic reticulum membrane to the cytoplasm.  Nuclear entry of the viral DNA involves the selective exposure and importin recognition of VP2 or VP3 nuclear localization signal (shared C-terminus).  Plays a role in virion assembly within the nucleus (By similarity).
What are the official names of this protein?
Minor capsid protein VP2, Minor structural protein VP2.
What is the protein family that this protein belongs to?
Belongs to the polyomaviruses capsid protein VP2 family.
What are the subcellular locations of this protein?
[Isoform VP2]: Virion. Host nucleus. Host endoplasmic reticulum. Host endoplasmic reticulum membrane. SUBCELLULAR LOCATION: [Isoform VP3]: Virion. Host nucleus. Host endoplasmic reticulum. Host endoplasmic reticulum membrane.
Protein: RL14_RICCK
Sequence: MIQMQSILEVADNSGAKKVMCIKVLGGSHHMVAKLGDVIVISVKEAIPGGKVKKGDVYKGVIVRTKTGVVRPDGSTIKFDKNALVLLNKQDEPIGTRVFGPVTRELRAKKYVRIMSLAEEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: LIF1_YEAST
Sequence: MSQLTEFISCIPVVNEEQNEEDERGLCKIQIEDGAMLETLDENSLSGLRIEKMLVSEGTGIFSKSSFGINDLRIFTGENIDEESKKYVWYELLKMLTGHKVYIASLDEKVVFTKWTCRMQDDEVWKVVMELESSAIIRKIAELTLHPVKKGEIDLFEMADKLYKDICCVNDSYRNIKESDSSNRNRVEQLARERELLDKLLETRDERTRAMMVTLLNEKKKKIRELHEILRQNNIKLSDDDVLDSALINTEVQKPISELNSPGKRMKRRKTVVEPQNLQKKLKDTSRRRANRKISNQSVIKMEDDDFDDFQFFGLSKRPIITAKDKLSEKYDDITSFGDDTQSISFESDSSSDVQKHLVSLEDNGIQISAGRSDEDYGDISGSESETDASAGEKKSSNHSEQSGNDREPCLQTESETDIET
What is the function of this protein?
Stabilizes DNL4.  Involved in non-homologous repair of DNA double-strand breaks.
What are the official names of this protein?
Ligase-interacting factor 1.
What is the protein family that this protein belongs to?
Belongs to the XRCC4-XLF family. XLF subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL35_BOVIN
Sequence: MAKIKARDLRGKKKEELLKQLEDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLNKHEENLKTKKQQRKERLYPLRKYAVKA
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BMP4_RABIT
Sequence: MIPGNRMLMVVLLCQVLLGGASHASLIPETGKKKVAEIQGHAGGRRSGQSHELLRDFEATLLQMFGLRRHPQPSKSAVIPDYMRDLYRLQSGEEEEEEQMPSGGLEYPERPASRANTVRSFHHEEHLENIPGTSENSAFRFLFNLSSIPENEAISSAELRLFREQVDQGPDWERGFHRINIYEVMKPPAEAVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNHGLAVEVTHFHHTRTHQGQHVRLSRSLLQGSGDWAQFRPLLVTFGHDGRGHALTRRRRAKRSLKHHPQRARKKNKNCRRHALYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHFNSTNHAIVQTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
What is the function of this protein?
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis (By similarity).  Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).  Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2.  Once all three components are bound together in a complex at the cell surface, BMPR2 phosphorylates and activates BMPR1A.  In turn, BMPR1A propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target genes.  Can also signal through non-canonical BMP pathways such as ERK/MAP kinase, PI3K/Akt, or SRC cascades.  For example, induces SRC phosphorylation which, in turn, activates VEGFR2, leading to an angiogenic response (By similarity).
What are the official names of this protein?
Bone morphogenetic protein 4, BMP-4.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: G6PI_PSEA6
Sequence: MTALTDTPTWQTLASLAEDVKQQHMRDWFASDTSRASKYQQTACGIELDFSKNLITDDVLKALFALADESQVSQKRDAMFKGDIINHTEKRAVLHTALRNFSGEPVYVDGQDVMPEVLACQDKIKDFVASIHSGERKGYTGKALKQIVSIGIGGSFLGPKIMSEALKPYWFDGVKVHFVANVDGCHIQDVLANLDHEETLVVMSSKSFTTQETLQNTLTAKDWFLNAGGTQQDIAKHFIAVSSNIKAATDFGMAEDNIFPMWDWVGGRYSLWSAIGLPIALTLGYDNYRQLLQGAFEMDEHFKTAPAEQNLPMLTALLGVWYINFFGAQSHVLLPYYHYLRGFPAYVQQLDMESNGKNISGDTTAVDYATGPIIWGSEGTNGQHSFHQLIHQGTLLIPADFMLPLNVPNQDNTHHAMLASNCFGQTQALMQGKTFDECYADLEGKGLDEAERVKLATHKTMPGNKPSNTLLFEQMDPKTLGSLVAMYEHKVFVQGAIWGVNSFDQWGVELGKELGNQVLDKIVNTDAALGFDSSTNALIARFRQANS
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU5C_STAPU
Sequence: MQLIDQYGWLIPLFPCLSALILGIGLLSFRRGTRSLRWASAAISIAFLGFSMMLSFGLFWDQILNNSAHIYIWSWITTEAVSLQIGYIIDPLSSIMLVLVTTVGIAVMIYTDGYMSHDQGYVRFFLYLSLFTASMLGLVLSSNLVQIYAFWELVGMCSYLLVGFWFSRPSAAAACQKAFVTNRVGDFGLLLGILGFYWITGSFDFETITTRFSELLNTNNVNVSFAIVCSLLLFLGPVAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLLPIFQNLPIVMDTIAITGVSTALLGATLALAQRDLKRGLAYSTMSQLGYMMLALGLGSYKVGLFHLITHAYSKALLFLGSGSVIHGMEPTVGYNPNKSQDMGYMGGIRKYMPVTGITFLIGTLSLCGIPPFACFWSKDEILANAWEKMPILGWIAWFTAGLTAFYMFRIYFLTFEGDFRGFIAKKDNKNTNKSGPHESSVNMVAPLVALSVPTIFIGFLGAPLVLGETSSLLFSKWLHVPDLHIEASELTWTEFALESLPSVGIAVTGACIAWIIYGPHASRNRNLVEFLDPSKKGILGVILNTIYNWSLRRGYIDELYNKTFISGTRNIANLFFVFDQWVIDGVVNNIGLLSLFGGESTRYGEVGRTTAYLFVLVITTFSLFGFFFILQ
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ATPMK_HUMAN
Sequence: MAGPESDAQYQFTGIKKYFNSYTLTGRMNCVLATYGSIALIVLYFKLRSKKTPAVKAT
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (PubMed:29917077).  ATP5MK is a minor subunit of the mitochondrial membrane ATP synthase required for dimerization of the ATP synthase complex and as such regulates ATP synthesis in the mitochondria (PubMed:21345788, PubMed:29917077).
What are the official names of this protein?
ATP synthase membrane subunit K, mitochondrial, ATP synthase membrane subunit DAPIT, mitochondrial, Diabetes-associated protein in insulin-sensitive tissues, HCV F-transactivated protein 2, Up-regulated during skeletal muscle growth protein 5.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: COX10_ARATH
Sequence: MWRRSVVYRFSSRISVSSSLPNPRLIPWSRELCAVNSFSQPPVSTESTAKLGITGVRSDANRVFATATAAATATATTGEISSRVAALAGLGHHYARCYWELSKAKLSMLVVATSGTGYILGTGNAAISFPGLCYTCAGTMMIAASANSLNQIFEISNDSKMKRTMLRPLPSGRISVPHAVAWATIAGASGACLLASKTNMLAAGLASANLVLYAFVYTPLKQLHPINTWVGAVVGAIPPLLGWAAASGQISYNSMILPAALYFWQIPHFMALAHLCRNDYAAGGYKMLSLFDPSGKRIAAVALRNCFYMIPLGFIAYDWGLTSSWFCLESTLLTLAIAATAFSFYRDRTMHKARKMFHASLLFLPVFMSGLLLHRVSNDNQQQLVEEAGLTNSVSGEVKTQRRKKRVAQPPVAYASAAPFPFLPAPSFYSP
What is the function of this protein?
Converts protoheme IX and farnesyl diphosphate to heme O.
What are the official names of this protein?
Protoheme IX farnesyltransferase, mitochondrial, Cytochrome c oxidase assembly protein COX10, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the ubiA prenyltransferase (TC 3.D.4.8) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ENO_STAAB
Sequence: MPIITDVYAREVLDSRGNPTVEVEVLTESGAFGRALVPSGASTGEHEAVELRDGDKSRYLGKGVTKAVENVNEIIAPEIIEGEFSVLDQVSIDKMMIALDGTPNKGKLGANAILGVSIAVARAAADLLGQPLYKYLGGFNGKQLPVPMMNIVNGGSHSDAPIAFQEFMILPVGATTFKESLRWGTEIFHNLKSILSKRGLETAVGDEGGFAPKFEGTEDAVETIIQAIEAAGYKPGEEVFLGFDCASSEFYENGVYDYSKFEGEHGAKRTAAEQVDYLEQLVDKYPIITIEDGMDENDWDGWKQLTERIGDRVQLVGDDLFVTNTEILAKGIENGIGNSILIKVNQIGTLTETFDAIEMAQKAGYTAVVSHRSGETEDTTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDELFETAKYDGIKSFYNLDK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: S19A1_RAT
Sequence: MVPTGQVAEKQACEEPRQDRELKSWRWLVFYLCFFGFMAQLRPGESFITPYLLERNFTKEQVTNEIIPMLPYSHLAVLVPIFLLTDYLRYKPVLVLQCLSFVCVWLLLLLGTSVVHMQLMEVFYSITMAARIAYSSYIFSLVQPSRYQRMASYSRAAVLLGVFISSVLGQVLVTLGGISTYMLNCISLGFILFSLSLSLFLKRPKRSLFFNRSALVQGALPCELDQMHPGPGRPEPRKLERMLGTCRDSFLVRMLSELVKNVRQPQLRLWCLWWVFNSAGYYLITYYVHVLWKITDSRLNYNGAVDAASTLLSAITAFTAGFVNIRWALWSKLVIASVIAIQAGLVFCMFQIPDIWVCYVTFVLFRGAYQFLVPIATFQIASSLSKELCALVFGINTFLATALKTSITLVVSDKRGLGLQVHQQFRIYFMYFLTLSIICLAWAGLDGLRYYRRGRHQPLAQAQALSPLEDSVQAISLQDGDLRRPQPSAPQLLPEDGSVEDGRADLRVEAKA
What is the function of this protein?
Antiporter that mediates the import of reduced folates (PubMed:11600421, PubMed:19243012).  Mechanistically, acts as a secondary active transporter, which exports intracellular organic anions down their concentration gradients to facilitate the uptake of its substrates (By similarity).  Has high affinity for N5-methyltetrahydrofolate, the predominant circulating form of folate (By similarity).  Also able to mediate the import of antifolate drug methotrexate (PubMed:10827155, PubMed:11600421).  5-amino-4-imidazolecarboxamide riboside (AICAR), when phosphorylated to AICAR monophosphate, can serve as an organic anion for antiporter activity (By similarity).
What are the official names of this protein?
Reduced folate transporter, Methotrexate carrier 1, MTX-1, MTX1, Plasma membrane folate antiporter SLC19A1, Reduced folate carrier 1, RFC-1, RFC1, Solute carrier family 19 member 1.
What is the protein family that this protein belongs to?
Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.
Protein: PEX29_YEAST
Sequence: MDSVTNFFWNDTYNAGTPTRSTLKGKKVQNGIDGKSQAKKESISSGSRTSDPTRGSLPSSSGQPTSGGGFPSTSNIQKMMADTLVEKIIKMALPPSSKTAVDTIHHRMVAGKERPKLSVQITSRNFIQMNSRLGVPFMIMDELIKILNWTNPAYTVSIMFLYTLIILKPFQMLSSLPIFYLLFCVMVPQYLYIHKPNPTSYLDNNQTPAQGPPLRRPEVPKPVPELSQEFVLNLTDLQNHMLLYVKFYDFTLLILQKFAFFTNEAISSFYFIVLLIIATLNFLYMDKFIKLIPMRPVLILLGWGFFIASHPSNREYLLTKLNSEETRLKTLTISTNLESKILQHLKLIEAREHRLVMIFEIQKYLPEYKEWRPVGFSDDDYSLFSSLRIYQRRIEENSVKSLEEIEPPKDWEWEANSHWVLDLDPKEWVEDEFIQYVEIDSETKWVYDLNLDGQRGSYRRRMWTNSCVRKKLDSGISSNLGEEEVVNPLREETYRQGVHGVTKGSMSGGLTHSSDDDRADEESINGTIPNLNNIDADASYPSIEELTDTLNSTI
What is the function of this protein?
Involved in the regulation of peroxisome number, size and distribution.
What are the official names of this protein?
Peroxisomal membrane protein PEX29, Peroxin-29.
What is the protein family that this protein belongs to?
Belongs to the PEX28-32 family. PEX29 subfamily.
Protein: MIAB_ECODH
Sequence: MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVLLLNTCSIREKAQEKVFHQLGRWKLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDIIFGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGSFADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRILNLMGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTEDFEKTMKLIADVNFDMSYSFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGTSRKSIMELSGRTENNRVVNFEGTPDMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRVAETPESVIARTRKENDLGVGYYQP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_BRUSI
Sequence: MSKRIAGPEIERLIQLLARVPGLGPRSARRAALHLIKKKEALLVPLGGAMQEAAEKVRICSCCGNVDTSDPCTICTDERRDPATLIVVEDVSDLWALERAGTMNVRYHVLGGRLSPLDGIGPDDLNIKGLVERVASGAIKEVILAVNATVEGQTTAHYITDQLSNFDVRVTRLAHGVPVGGELDYLDEGTLAAALRARTTL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: DDL_METPB
Sequence: MSKHVAVLMGGWSSEREISLRSGNACAEALEGEGYRVTRVDVGPDIATVLTDLKPDAALNALHGPAGEDGTIQGLLEILKIPYTHSGVLASALAMHKERAKTVMRAAGVSVPEGRVVNRHDAAKSHPLTPPYVVKPIAEGSSMGVIIVREERSHPPQILASDEWVYGEEVLAETYIAGRELTCAVLGDRALGVTEIKPVSGEWYDFDAKYAGGGSIHVLPADLKLNIYQRVQELALTAHQALGCRGVSRADLRYDDTPGGTGALVVLEVNTQPGMTQTSLVPEIAAHAGLSFGELVRWMVEDASLNR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRP36_PENRW
Sequence: MAISDLLNRRVRARPEDDEVYSEASGSDEGSQDGSDAESNGSIHSQEDDSDAEGDGDDTDADSQSEASNSDIEEEPESEHDDGDDFKASLADISFGALAKAQASMREKNRKDKRTPKDDTASSTVDDIRTKLREAREQKLEAAAKSKSKEKKSRSSKHAPMELSSKRAVTRKRTAVELPPAPRSRDPRFDAAVMGHSGVGKHPHGGKAYAFLDEYRASELNDLKEQMRKTKNLQQKEKLKGEIRRMQDKLRSAQNKKREAEVQAEHKKREKQLIREGKKANPYYLKNSELQKQVLERKYGEMGSRERAKALERRRRKMASKERKEMPWERRGAGGDEDGGAPNGGKRRRLE
What is the function of this protein?
Component of the 90S pre-ribosome involved in the maturation of rRNAs.  Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
What are the official names of this protein?
rRNA biogenesis protein rrp36, Ribosomal RNA-processing protein 36.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: YMC2_SCHPO
Sequence: NLIGLLTLLYAGTTWKILDKSFCFKYSKKNTRLVFIFIVKMLKQLSISAGNLLNKGTSETLRNEITTKKVSIHLPKHLKPANDSQFGHYLAGLIDGDGHFSSKQQLIIAFHSLDIQLAYYIKKQIGYGIVRKIKDKNAILFIIANSKGIERVITLINNKFRTTSKYNQIINNIFAHPRFKEFSKTITLGLNSNNNLNNHWLAGFSDADASFQIKILNRDKKIEVRLNYQIDQKKEYLLSLIKDNLGGNIGYRKSQDTYYYGSTSFGSAKKVINYFDNYHLLSSKYISYLKWRKAYLIIQENKHLTESGLSQIKKPHPYRKNIN
What are the official names of this protein?
Uncharacterized cox1 intron-2 37.2 kDa protein, Probable maturase.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RRF_CLOD6
Sequence: MKLEIHKQLEEKMNGTIDALKFEFGTIRAGRANAQMLDKIRVDYYGTPTPINQIGAISVPEPRILMISPWDKSAMHEIEKAIANSDLGLNPSNDGEVIRLSVPALTEERRKELAKKASKAAEEFKVRIRNERRDANEKIKKMEKGGELTEDELKKAQDEVQKMTDKFIKEIDTLLSKKEKDIMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBP6_YEAST
Sequence: MSGETFEFNIRHSGKVYPITLSTDATSADLKSKAEELTQVPSARQKYMVKGGLSGEESIKIYPLIKPGSTVMLLGTPDANLISKPAKKNNFIEDLAPEQQVQQFAQLPVGFKNMGNTCYLNATLQALYRVNDLRDMILNYNPSQGVSNSGAQDEEIHKQIVIEMKRCFENLQNKSFKSVLPIVLLNTLRKCYPQFAERDSQGGFYKQQDAEELFTQLFHSMSIVFGDKFSEDFRIQFKTTIKDTANDNDITVKENESDSKLQCHISGTTNFMRNGLLEGLNEKIEKRSDLTGANSIYSVEKKISRLPKFLTVQYVRFFWKRSTNKKSKILRKVVFPFQLDVADMLTPEYAAEKVKVRDELRKVEKEKNEKEREIKRRKFDPSSSENVMTPREQYETQVALNESEKDQWLEEYKKHFPPNLEKGENPSCVYNLIGVITHQGANSESGHYQAFIRDELDENKWYKFNDDKVSVVEKEKIESLAGGGESDSALILMYKGFGL
What is the function of this protein?
Predominant proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins.  Ensures the regeneration of ubiquitin at the proteasome.  Has proteasome-inhibitory activity and delays the degradation of ubiquitinated proteins to provide a time window allowing gradual deubiquitination of the substrate.  Stabilizes the association of HUL5 with proteasomes and works in opposition to polyubiquitin elongation activity of HUL5.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 6, Deubiquitinating enzyme 6, Ubiquitin thioesterase 6, Ubiquitin-specific-processing protease 6.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP14/UBP6 subfamily.
Protein: TUS_ECOSE
Sequence: MARYDLVDRLNTTFRQMEQELATFAAHLEQHKLLVARVFSLPEVKKEDEHNPLNRIEVKQHLGNDAQSLALRHFRHLFIQQQSENRSSKAAVRLPGVLCYQVDNLSQAALVSHIQHINKLKTTFEHIVTVESELPTAARFEWVHRHLPGLITLNAYRTLTVLHDPATLRFGWANKHIIKNLHRDEVLAQLEKSLKSPRSVAPWTREEWQRKLEREYQDIAALPQNAKLKIKRPVKVQPIARVWYKGDQKQVQHACPTPLIALINRDNGAGVPDVGELLNYDADNVQHRYKPQAQPLRLIIPRLHLYVAD
What is the function of this protein?
Trans-acting protein required for termination of DNA replication.  Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks.  The termination efficiency will be affected by the affinity of this protein for the terminator sequence.
What are the official names of this protein?
DNA replication terminus site-binding protein, Ter-binding protein.
What is the protein family that this protein belongs to?
Belongs to the Tus family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y476_MYCTU
Sequence: MLVLLVAVLVTAVYAFVHAALQRPDAYTAADKLTKPVWLVILGAAVALASILYPVLGVLGMAMSACASGVYLVDVRPKLLEIQGKSR
What are the official names of this protein?
Uncharacterized protein Rv0476.
What is the protein family that this protein belongs to?
To M.leprae ML2453.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MUTS_BACCQ
Sequence: MTQYTPMIQQYLKVKADYQDAFLFFRLGDFYEMFFEDAVKAAHELEITLTSRDGGSSERIPMCGVPYHAAKNYIEQLVEKGYKVAVCEQVEDPKTAKGVVRREVVQLITPGTMMEGRTIDEKENNFLAALTHFEDGSYALACNDLTTGQNTVTLLTGSVEDILLEVYATGSKEIVVDSSFSKDELNKLTETLKMTISYEDATAIPEGLEHLVKNVSQAKLIKAVGRLFNYVIRTQKRSLDHLQPVEIYYTNQFMKIDVHSKRNLELTETLRTKEKTGSLLWLLDKTKTAMGGRMLKQWMERPLIQKERIEERLEMVETFVNDYFLREDLKEKLKEVYDLERLAGKVAFGNVNARDLLQLRRSLLQVPAILEAISLLDNAYAARLIQGADPCESLTELLGRSIQENPPLSIKDGDIIKDGYNDKLDQYRYVSKNGKTWIAELEKRERDITGIKSLKIGYNRIFGYYIEVTKANLGALPEGRYERKQTLANAERFITDELKEKETLILEAEEKIVQLEYDLFTALREEVKVFIPKLQHLAKVISELDVLQSFATVSEEEQFVKPVLTTKREIFIKDGRHPVVEKVLNGKLYVPNDCIMPENMDVFLITGPNMSGKSTYMRQLALVTVMSQIGCFVPATEAVLPVFDQIFTRIGAADDLISGQSTFMVEMLEAKNAIANASERSLILFDEIGRGTSTYDGMALAQAIIEHIHDQIGAKTLFSTHYHELTVLEESLDQLKNVHVSAIEENGKVVFLHKIQDGAADKSYGIHVAQLAELPDSLIARAKEVLAQLEGQEEIIIPKRVEVKMQEQEVIPEPVVVKEAPVEIEETKVENEEESQLSFFGGEQSPKKQDKPVLDTKETAVLAQIKKIDLLDMTPLEAMNELYRLQKKLKKG
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RS6_GEOMG
Sequence: MVRKYETVVIVQPDLGDDELKGLNAKVTDIIATMKGDLHRLEDWGVRKLAYPINKSARGRYYYVRFDGDAALIAELERRLRLDDKVLRYQSVKIEKETAAPAAKVAPVETAPAAEAAE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: TRMD_ONYPE
Sequence: MIIEIITIFPLFFKSFCETSIIKRALEQKKVQIKLHDLRTYSKNKHNQVDDSVYGGGVGMLLSFPPFFDCLQKIKTPQSKVILLSPQGKIFNQIHATNFAQKETHLIILCGNYEGVDARILQYIDAEISIGDYVLTGGEIAATVLVDAITRLLPEVIKEQSFLEDSHQQGLLKHPQYTRPQSYLNHEVPAVLLSGNHAKIRCWRQKESLKATLQKRPDLLENKKLTLEQTKLLTEIKQELQK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.