PharMolix/UniProtQA huggingface dataset:
Protein: CP1A2_CALJA
Sequence: MALSQFVPFSATELLLTSTVFCLVFWVFKGLRPRVPKGLKSPPEPWRWPLLGHVLTLGKNPHLALTKMSQRYGDVLQIHIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYSFTLITDGQSMSFSPDSGPVWAARRRLAQNALNTFSIASDPASSSSCYLEEHVSKEAEALIGRLQELMAGPGRFDPYNQIVESVVKVIGAMCFGQHFPESSDEMLSLMKNSHVFVENATSGNPVDFFPILRYLPNPALQRFKAFNQRFLRFLRETVQEHYQDSDKNSVQDITGALFKHCEKRSGASGDLIPQEKIVNLVNDIFGAGFDTITTAISWSLMYLVTKPEIQRKIQKELDTVIGRGRRPRLSDRPQLPYLEAFILETFRHSSFVPFTIPHSTTRDTTLKGFYIPKECCVFINQWQVNHDPQLWGDPSEFRPERFLTAKGTALNKPLSEKILLFGLGKRRCIGEVLGKWEVFLFLAILLQQLEFSVPPGVQIDLTPTYGLTMKHARCEHVQARLRFSFQ
What is the function of this protein?
A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase).  Catalyzes the hydroxylation of carbon-hydrogen bonds.  Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E2.  Metabolizes cholesterol toward 25-hydroxycholesterol, a physiological regulator of cellular cholesterol homeostasis.  May act as a major enzyme for all-trans retinoic acid biosynthesis in the liver.  Catalyzes two successive oxidative transformation of all-trans retinol to all-trans retinal and then to the active form all-trans retinoic acid.  Primarily catalyzes stereoselective epoxidation of the last double bond of polyunsaturated fatty acids (PUFA), displaying a strong preference for the (R,S) stereoisomer.  Catalyzes bisallylic hydroxylation and omega-1 hydroxylation of PUFA.  May also participate in eicosanoids metabolism by converting hydroperoxide species into oxo metabolites (lipoxygenase-like reaction, NADPH-independent).  Plays a role in the oxidative metabolism of xenobiotics.  Catalyzes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.  Metabolizes caffeine via N3-demethylation.
What are the official names of this protein?
Cytochrome P450 1A2, CYPIA2, Cholesterol 25-hydroxylase, Hydroperoxy icosatetraenoate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: YTUB_ENTAG
Sequence: MPNKLLSANATVPQWDRHNLVPRIVHLGFGAFHRAHQAVYADVLAAEHSSDWGYIEVNLIGGEQQIADLKCQDFLYTVAEMSASAWSGRVVGVVRQALHAQVDGTEAVLEALCQPQVAIVSLTITEKGYCHAPATGELMRDHPLIVADLAQPHQPHSAPGIIVEALARRRAAGLAAFSVMSCDNIPENGRVIAGVVCAYARQCD
What are the official names of this protein?
Uncharacterized oxidoreductase in tutB 3'region.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: HIS7_XANAC
Sequence: MTPILFVDRDGTLIVEPADYQIDAYEKLRLVDHVIPAMLKLRDAGYQFVIVSNQDGLGSESYPRASFDGPNNLMLQIFASQGIEFREVLIDCSWPADNAPTRKPGIGLMVPYLQDRTIDWARSAMVGDRITDIQFAQNLNIRGFQLRTDEFGGEWDWSGIAHELADAPRRALVQRNTKETRIRVELDLDRVAEPKTATGLPFFDHMLEQIGKHGGFALEIRAEGDLHIDEHHTIEDTGLALGQALREALGDKRGIGRYGFDPESSPWRVAGDTPQHGFTLPMDETIASAALDFSGRPYFVFEGEFKRERVGDMPTELVPHFFRSICDASGLNLHLTVRGENDHHKVEACFKALARALRQAIRREGTALPTTKGTL
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisB.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_BURVG
Sequence: MSEKTVKVQLVKSLIGTRESHRATVRGLGLRRLNSVSELQDTPAVRGMINKVSYLVKVIA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: CT5A_CONCN
Sequence: ECCHRQLLCCLRFV
What is the function of this protein?
Interacts selectively with the G-coupled somatostatin sst3 receptor (SSTR3).  It displays antagonist property for SSTR3 (Ki=1. 5 uM).  Other somatostatin receptors are also affected, but with a lower selectivity: SSTR5 (Ki=80. 2 uM), SSTR1 (Ki=169 uM), SSTR2 (KI=159 uM), SSTR4 (Ki>100 uM).
What are the official names of this protein?
Tau-conotoxin CnVA, Tau-CnVA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CDF2_ARATH
Sequence: MADPAIKLFGKTIPLPELGVVDSSSSYTGFLTETQIPVRLSDSCTGDDDDEEMGDSGLGREEGDDVGDGGGESETDKKEEKDSECQEESLRNESNDVTTTTSGITEKTETTKAAKTNEESGGTACSQEGKLKKPDKILPCPRCNSMETKFCYYNNYNVNQPRHFCKKCQRYWTAGGTMRNVPVGAGRRKNKSPASHYNRHVSITSAEAMQKVARTDLQHPNGANLLTFGSDSVLCESMASGLNLVEKSLLKTQTVLQEPNEGLKITVPLNQTNEEAGTVSPLPKVPCFPGPPPTWPYAWNGVSWTILPFYPPPAYWSCPGVSPGAWNSFTWMPQPNSPSGSNPNSPTLGKHSRDENAAEPGTAFDETESLGREKSKPERCLWVPKTLRIDDPEEAAKSSIWETLGIKKDENADTFGAFRSSTKEKSSLSEGRLPGRRPELQANPAALSRSANFHESS
What is the function of this protein?
Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity).  Regulates a photoperiodic flowering response.  Transcriptional repressor of 'CONSTANS' expression.  The stability of CDF2 is controlled by 'GIGANTEA' and redundantly by ADO3, ADO2 and/or ADO1.
What are the official names of this protein?
Cyclic dof factor 2, Dof zinc finger protein DOF5.2, AtDOF5.2.
What are the subcellular locations of this protein?
Nucleus.
Protein: KAD_RICCN
Sequence: MMVIFLGPPGAGKGTQGKKIAKKIDLPHIAIGDIFRTIIKTSTSEAELINNYVKQGELIPNEIVNQVIKNFLLSSEYKNGYILDGYPRNLEQAKFFESFIKEKIKIIYFDVSDELLIKRILGRYSCKNCGKIYNRYFVQPKTDNVCDVCGSSTFDYRKDDNEEVIKKRIEVYKTETYPLIDYYKNSGNFYIVNGSKNEQEIEIDIQKILKIN
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y649_ARCFU
Sequence: MRRFKFQYKETIVTILTENEEFYKTAVKAILEARSEIEDYILHNPDFFTSYEPIECSGGEIINRMCNAAKIAGVGPMAAVAGTIAAYAVEKMIDAGAKLAVVDNGGDIVIHSDRELLVGIYPSKLAFKVPPVDYLAICTSSGKIGHSVSFGKADAATVVARDASVADALATALGNLIGDFGKKELEKTVSEFYGKYSDFVEGILVVKDELVALAGNLPSLAFAESKEDLITKG
What are the official names of this protein?
UPF0280 protein AF_0649.
What is the protein family that this protein belongs to?
Belongs to the UPF0280 family.
Protein: TPCD_RANDY
Sequence: MFTLKKSMLLLLFLGTISLTLCEEERDANEEEENGGEVKEEEKRFIGPLISALASLFKG
What is the function of this protein?
Antimicrobial peptide.
What are the official names of this protein?
Temporin-CDYd.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Temporin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: A1AT3_HORSE
Sequence: EDLQGDAVPEEXATKDDNEHPQTLLLTNVEFNXRPFVLIIYDRNTKSPLFVG
What are the official names of this protein?
Alpha-1-antiproteinase 3, Alpha-1-antitrypsin 3, Alpha-1-proteinase inhibitor 3, SPI3.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRD_YERPE
Sequence: MYYPLVRKALFQLDPERAHELTFRQLKRVSGTPLEFLVRQSVPTKPVSCMGLSFKNPVGLAAGLDKDGECIDALGAMGFGFIEVGTVTPRPQVGNDKPRLFRIVEAEGLINRMGFNNHGVDNLIENVKKSHFGGILGINIGKNKDTPVEQGKEDYLICMDKIYPYAGYIAINISSPNTPGLRSLQYGEALDDLLAAIKDKQTELHQRHHKYVPVAVKIAPDLTEEELIQIADSLVRHNIDGVIATNTTLDRSLIQGLNYCEQAGGLSGRPLQLRSTEVIHRLSQELKGRLPIIGVGGIDSVTAAREKMAAGASLIQIYSGFIFRGPGLIKNIVTHI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RBL_ILEAQ
Sequence: MSPQTETKASVGFKAGVKDYKLTYYTPDYVTKDTDILAAFRVSPQPGVPPEEAG
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site (By similarity).
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: THIC_CAMFF
Sequence: MRKDWCEARKNDPTPTQMYYAKNGVITPEMEYVAKVEMLKPEYIRQLVAEGKLIIPANINHTNQIPMAIGRAVKCKINANIGSSALASDINEEIEKLKVCLKYGADTVMDLSTGGDLDEIRRAIIANSTVPIGTVPIYQIIHDIKDLDNLTPQIMLECIEKQAKQGVSYFTIHAGFLLKFMPLVAKRKMGIVSRGGSLMASWMMKHHKENPFYEAFDEICDICAKYDASLSLGDSLRPGCLHDASDEAQMSELAVLGELTKRAWEKNVQVMVEGPGHVPFNQIEFNMKEEKRLCHDAPFYILGPLPTDIGAGYDHITSAIGGTMAAFHGASMLCYVTPKEHLGLPNAKDVRDGIISHKIAAHAADIALGRVGAIERDHAMSDARYKFDWNKQFELALDPDKARELHDESLPQDVFKEAEFCSMCGPKFCAYKISQEIAKIECSDYPKEKK
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: CNTD1_MOUSE
Sequence: MNMEGPLRPRLVNCSDFQFGVVTTETIENALLHLAQQNEQAVKEAAGRTGSFRETRIVEFVFLLSEQWCLEKSVSYQAVEILERFMLKQAEDICRQATLQLRGKDTELQSWRAMKEQLVNKFILRLVSCVQLASKLSFHYKIVSNITVLNFLQALGYVHTKEELLESELDILKSLNFQINLPTPLAYVEMLLEVLGYNGCLVPATQLHATCLTLLDLVYLLHEPIYESLLRASIENSTPSQLQGEKFLSVKEDFMLLAVGIIAASAFIQNHECWSQVIGHLQSITGIASESIAEFSYAILTHSVGANTPGPQQPVPHKAARALRTAAAAASSNT
What is the function of this protein?
Plays a role in the different steps of crossover formation during meiotic recombination (PubMed:24891606, PubMed:32640224, PubMed:32555348).  Participates in the crossover differentiation step of crossover-specific recombination intermediates through its interaction with PRR19 (PubMed:32555348).  In addition, stimulates crossover formation through the interactions with RFC3 and RFC4 and simultaneously regulates cell-cycle progression through interactions with CDC34 and subsequent ubiquitination of WEE1 (PubMed:32640224).  May also participates in an active deselection process that destabilizes or removes excess pre-CO intermediates (PubMed:24891606).
What are the official names of this protein?
Cyclin N-terminal domain-containing protein 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome. Note=Shuttles between the nucleus and cytoplasm in a stage-specific manner of prophase I cells (PubMed:32640224). Co-localized at crossover sites with PRR19 (PubMed:32555348).
Protein: FAR5_AUSGA
Sequence: TDRNFLRL
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-5, FMRFa-5.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PIMT2_ARCFU
Sequence: MDYDEKRERLAERLRQELNLSRKVYEAIRKVPRHLFVPESYKNEAYVDTPLPIGYGQTISAPHMVAIMCELLDLREGDKVLEVGTGCGYHAAVTAEIVGKSGKVISIEYIPELAERARAILKALGYDNVEVIVGDGSKGYEKEAPYDKIYVTAAAPDIPKPLIEQLKPRGRMVIPVGDSVQWLIIVEKDESGNVRKKNWGSVRFVPLRGEYGFKSVRYD
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins (By similarity).
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase 2, L-isoaspartyl protein carboxyl methyltransferase 2, Protein L-isoaspartyl methyltransferase 2, Protein-beta-aspartate methyltransferase 2, PIMT 2.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPH_RHOCA
Sequence: MAPALIFDLDGTLIDSAPAIHKVSNDVLRARGYAPLGLDQIRSFVGQGAPHLVRCLLTTAGEDPEGPLFDAIYADLVSRYETDVEGNTLYPGVITALQRLREMGCPMAITTNKPYKPALAAIAHVGLTDYFQLVIGGDSLPTRKPNPEMVNEARRVLRRPHALYIGDSEIDAQTAQNAGLPFVIYTEGYRKTPLDALPHAAKFHDFSALPGIVEGWTWS
What is the function of this protein?
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.  Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity).
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: SYN_STAAT
Sequence: MKTTIKQAKDHLNQDVTIGAWLTNKRSSGKIAFLQLRDGTGFMQGVVVKSEVDEEVFKLAKEITQESSLYVTGTITEDNRSDLGYEMQVKSIEVISEAHDYPITPKNHGTEFLMDHRHLWLRSKKQHAVMKIRNEVIRATYEFFNKDGFTKVDPPILTASAPEGTSELFHTKYFDQDAFLSQSGQLYLEAAAMAHGKVFSFGPTFRAEKSKTRRHLIEFWMIEGEMAFTNHAESLEIQEQYVTHVVKSVLENCKLELKILERDTSKLEKVATPFPRISYDDAIEFLKAEGFDDIEWGEDFGAPHETAIANHYDLPVFITNYPTKIKPFYMQPNPENEETVLCADLIAPEGYGEIIGGSERVDDLELLEQRVKEHGLDEEAYSYYLDLRRYGSVPHCGFGLGLERTVAWISGVEHVRETAPFPRLLNRLYP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIC_SACD2
Sequence: MTTDTLEKPRLSDTAQVDSQSIAPFPNSKKIYVQGSRPDIRVPMREINLSITPTEFGGEQNPPVRVYDTSGVYTDPNVKIDVRQGLPDVRSAWIAERGDTEVLQQKSSSFTQQRLHDASLDTLRFNHQRQPLKAKPRANVTQMHYARCGIITPEMEYIAIRENMSWQQAKEQGVLDQQHAGEHFGANIPDEITPEFVRSEVACGRAIIPANINHPELEPMIIGRNFLVKINGNIGNSAVTSSIEEEVAKLTWGTRWGADTIMDLSTGKNIHETREWIIRNSSVPIGTVPIYQALEKVDGVAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHRENFLYTHFEDICEIMKAYDVSFSLGDGLRPGSIADANDEAQFGELETLGELTKIAWKHDVQVMIEGPGHVPMHMIKENMDKQLRECGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWYGCAMLCYVTPKEHLGLPNKDDVKEGIITYKIAAHAADLAKGHPGAQLRDNALSKARFEFRWEDQFNLGLDPDTARSYHDETLPKDSAKVAHFCSMCGPKFCSMKITQEVRDYAAEHGTDITPIAEDEVVRMIDVEAEMRKKSEEFREKGSEIYGKI
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: NTPPA_SHESR
Sequence: MNLVLASTSPRRKELLTHIGLGRAEFSFSQVAPDIDETPKAGELPRDYVQRLAAEKALAGLALCSGMSQPAVLGSDTIVVLENEILGKPVDEADAKRVLRALSGKAHTVMTAVALAKADQTSVRLVETLVRFCVLSDADIDAYVASQEPMDKAGSYGIQGLGGCFVESIEGSYSCVVGLPLVETRELLSEAGIR
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMO1_CHATD
Sequence: MTVCRFWQQGYCRNGNACKFEHPPKGGQNYNRFGALSGSGQGMGGRVSEPPHYPGLSEDAIQKDLTSELPTWILSCYGPGRDAPEQLFGGYPREQSFEEIRLHFYNGLMAGNPQGALNEIQAAYQAAQQQIQNTLQNIPAAVQFILDAANKHPNRIDICRESSKGSSTGGSVFGRNVNPFQQSSAAPLNPFGAPSTPSTSAFGQPSPLGQKSSAFGTPAFGQPSQPVSAFGKPSALGGGSAFGSPQTGSTFGQPSVLGAKPSAFGQPAFGQPAFGQPAFGQSAFGQPSALGPKPGAFGTSAGSAFGASTTTAPSPFGAAAQATQPANPFGQPSQQAANSFGKPAAPASAFGQPSTTTAQNPFGQPSTQSSAFGQQQPQQAGTFGSPSLFGQQQQQPSNVFGQPSTTSAFGSQAATSGFSQLGNATSTIGASPAGAQAPASKSPYHPGSTRQHPDLLSYATKNPAGGLDTFKGKPVVYETPKGAAKPVPHIRQFDGTLVRIWMPDGAPAYTADTEAEDPKVYEDEGVKRQWQSFLEKGRFEGGMPEVPPRREWCVWDF
What is the function of this protein?
Functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with GTP in the nucleus, with GDP in the cytoplasm).  AMO1 is specifically important for nuclear protein and mRNA export.
What are the official names of this protein?
Nucleoporin AMO1, Nuclear pore protein AMO1.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RSMH_CLOPE
Sequence: MEFKHVSVLLDECINALNIKEDGIYVDCTLGGAGHSSEIVKRLSSDGRLIRFDQDKDALKAAGERLKDYKNVTYVHSNFYAIYDVLTDLGIDGVDGILMDLGVSSYQLDNGERGFSYMQDAPLDMRMNRENEFSAYEIVNTYSEEELYRIIKEYGEEKFAKRIASFIVKNREEKNIETTLELVEIIKAAIPAKARREGPHPAKRTFQAIRIEVNKELEIISKTILDGVKKLNKGGRMAIITFHSLEDRIVKNTFKELANPCTCPSEFPVCVCNRKPEVKLISRKPIEASKEELEFNPRSRSAKLRIIEKL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_KLEP7
Sequence: MLDNTRLRIAIQKSGRLSEDSRELLSRCGIKVNLHTQRLIALAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLSRRAQGEDPRYFTLRRLDFGGCRLSLATPVDEAWNGPAALDGKRIATSYPHLLKRYLDQKGISFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMADAKQQLIDRLLTRIQGVIQARESKYIMMHAPTERLEEVVALLPGAERPTILPLAGDKQRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_HAEIE
Sequence: MKVAVLGAAGGIGQALALLLKLQLPAGTDLALYDIAPVTPGVAVDVSHIPTAVNVKGFSGEDPTPALEGADVVLISAGVARKPGMDRSDLFNINAGIVRGLIEKVAVTCPKACVGIITNPVNTTVAIAAEVLKKAGVYDKRKLFGVTTLDVLRSETFVAELKGLNVSRTSVPVIGGHSGVTILPLLSQVQYAKWNEDEIEPLTKRIQNAGTEVVNAKAGGGSATLSMAQAAARFARSLVKGLSGETVVECTYVEGDGKYARFFSQPVRLGKEGVEEILPIGPLSNFEQQALENMLPTLHADIELGEKFING
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: XYNC_ASPFC
Sequence: MVVLSKLVSSILFVSLVSAGVIEERQAASINQAFTSHGKKYFGTASDQALLQKSQNEAIVRKDFGQLTPENSMKWDATEPSQGRFNFAGADFLVNYAKQNGKKVRGHTLVWHSQLPSWVSAISDKNTLTSVLKNHITTVMTRYKGQIYAWDVVNEIFNEDGSLRDSVFSRVLGEDFVRIAFETARSVDPSAKLYINDYNLDSASYGKTQGMVRYVKKWLAAGIPIDGIGTQTHLGALTALASSGVSEVAITELDIAGASSQDYVNVVKACLDVPKCVGITVWGVSDRDSWRSGSSPLLFDSNYQPKAAYNAIIAAL
What is the function of this protein?
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Probable endo-1,4-beta-xylanase C, Xylanase C, 1,4-beta-D-xylan xylanohydrolase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 10 (cellulase F) family.
What are the subcellular locations of this protein?
Secreted.
Protein: NFYB_HORSE
Sequence: MTMDGDSSTTDASQLGISADYIGGSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYLPIANVARIMKNAIPQTGKIAKDAKECVQECVSEFISFITSEASERCHQEKRKTINGEDILFAMSTLGFDSYVEPLKLYLQKFREAMKGEKGIGGAVTATDGLSEELAEEAFTNQLPAGLITADGQQQNVMVYTTSYHQISGVQQIQFS
What is the function of this protein?
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.  NF-Y can function as both an activator and a repressor, depending on its interacting cofactors (By similarity).
What are the official names of this protein?
Nuclear transcription factor Y subunit beta, CAAT box DNA-binding protein subunit B, Nuclear transcription factor Y subunit B, NF-YB.
What is the protein family that this protein belongs to?
Belongs to the NFYB/HAP3 subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: F133B_RAT
Sequence: MGKRDNRVAYMNPIAMARSRGPIQSSGPTIQDYLNRPRPTWEEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGNESSSKKRQKKKKEKKKSGRYSSSSSSSSDSSSSSSDSEEEDKKQTKRRKKKKSHCHKSPETSVSDSDSDSKDGSKKKKKSKDITEREKDTKGLSKKRKMYEDKPLSSESLSESDCGEVQAKKKKSGEERERTTDKAKKRRKHKKHSKKKKKKAASSSSDSP
What are the official names of this protein?
Protein FAM133B.
What is the protein family that this protein belongs to?
Belongs to the FAM133 family.
Protein: Y534_THEGJ
Sequence: MESLFLLVLGNTEISTVPGISVAGATPELTKLTPVADAEYLFHEKPLTIDVIPVTPEGHPTPAIITKAARELANFPVLVVRGGTYLAPLVPHVHISDAVGRDFRKEPALPEFGDIIKRAKLFGEELNKTPIKELVIGESTPGGTTTAQAVLWALGYEARTSSASPDNPQSLKEKVIAEAFERAGIEKGQLRDNPLEALRQFGDPMMATVIGIALGFRRDIVLAGGTQMLAVSALLKALGEDLSRFMIATTKWVANDKSATFIETAKEIGIISYAADLDFSKSEFKGLRDYERGYVKEGVGAGGATWLAVKAGFSPEDVSEKVEELYRRLMEMK
What are the official names of this protein?
UPF0284 protein TGAM_0534.
What is the protein family that this protein belongs to?
Belongs to the UPF0284 family.
Protein: MUTS_LACPL
Sequence: MPQKTKDTPMMRQYFAVKNQYPDAFLFYRLGDFYEMFFDDAIKGAQLLELTLTTRNHSAENPIPMCGVPHRAVQNYIDILVDKGYKVAICEQMEDPKLAKGMVKREVIQLVTPGTTLERGAEQAKTNNYLTALIQRDQQYGFAYADLSTGELKTSVLTTNDTLINELTSLQTKEIVVDDSVASDLRDQIKTLGILISEQNNVTPQAQLSYLTQDLTVDLEQQVVERLLMYITVTQKRSLAHLQKAIAYEPSYFLKLDHNSKYNLELMKSIRTGKKQGTLLWLLDETKTAMGGRLLKQWIDRPLIVKADIETRQNKVATLLDHYFERSNLQEELTKVYDLERLAGRVAFGSVNGRDLVQLKTSLRQIPKIRYILSELDTQVFNDEVNQLDPVEDVADLIDAAIVEDAPLSVTDGGVIKDGYNEQLDQYRDAMNNGKKWIAELEAQERATTGIKNLKIGFNRVFGYYIEVTKANLAQLPKDRYERKQTLTNAERFSTPELKSHESLILEAESHSTDLEYQLFTKVRETVKKAIQRLQTLAKAVAAIDVLQSFAVVSEDYHFVRPKLTKSHDLKIVDGRHPVVEKVMGNQSYVPNNVTMSPDETVLLITGPNMSGKSTYMRQLALTVIMAQIGCFVPAKSAQLPIFDQIFTRIGATDDLISGQSTFMVEMQEANNALQHATANSLVLFDEIGRGTATYDGMALAQAIIEFVHNHIHAKTLFSTHYHELTALDQELSGLRNVHVGATEQDGELVFLHKVEPGAADKSYGVHVAKLAGMPTSLLERANKILTSLENQTSTVSTTAASIAASDAANSVAPNTAASMPVEAADESQPVESETPVAEAPVAEAGDEQLSLFAEPAVTDAKGEKVLQQLKTLNLMAMTPMDVMNQLYKWQQKLGK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.