PharMolix/UniProtQA huggingface dataset:
Protein: AC4CH_SALDC
Sequence: MQPNDITFFQRFQNDILAGRKTITIRDVSESHFKAGDVLRVGRFEDDGYFCTIEVTGTSTVTLDTLNEKHAQQENMSLDELKRVIAEIYPNQTQFYVIDFKCLR
What is the function of this protein?
Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).
What are the official names of this protein?
N(4)-acetylcytidine amidohydrolase, ac4C amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the N(4)-acetylcytidine amidohydrolase family.
Protein: RL38_AERPE
Sequence: MPVELKSFDEFVKVVERAVECRVKRGKDVVKIKARTKRYLYTLKVPPEKEAEVLEQVKAKCKNLVEL
What are the official names of this protein?
50S ribosomal protein L38E.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL38 family.
Protein: RLMKL_SHEPA
Sequence: MLNFFAAAPRGYEYALSLELAELGASEIKESVAGVYFSAPLELGYRITLWSRLASRIIFVIYKGPCESPEQLYNAAYGIDWQMQFSNRSTFSIDFHGLGGFIKNTQFGALKIKDAIVDRFRDDDFSRPNVERVDADFRIDAHFRRGEITIGINFSGPALHKRGYRSTTGEAPLKENLAANMLVRSGWQADKVDLLDPFCGSGTILIEAAMMACDIAPGIHRERFGFDHWLPHNKKVWQELLNEAQARASIGKTRCEIKFFGSDIDSRLVALAKRNAENAGVLELIDFSVGNALTIDVPVESGFLISNPPYGERLGNVTSLLQLYYQLGDKFKAEFGGWSIAILNSDIELLSALKLKADKQMKMNNGALECAFNLYTVHAENTRRVDPANIKIEGDVSDIAVPFANRIKKNFKQLEKWAKKEGIDSYRLYDADLPEYNVAVDKYLDYVVIQEYSAPSQIPEAVTKRRLTDVLISLPSAIGIDPNHIILKTRERKKGTNQYEKLVANKLELITTEYGAKFKLNLKEYLDTGLFLDHRLTRKLVGEKSKGRSVCNLFSYTGSASVHAALGGATSVTTVDMSNTYIDWAKENFALNGLNSDKYQFVQANCLQWMKRTHDRFDLIFIDPPTFSNSKRMEDSFDVERDHVAMLSDVFKLLNPGGEIIFSNNKRKFKMEIAALEAQGMSIKNIDNQTLPLDFKRNPHIHNTWLITHAG
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAAN_BACSU
Sequence: MNRDQSDLHIDELLADPFGGNIEIPGSEAVKAEKEQVRLVDVLPEENKEKAIQLAGQIDHKNMQSIVLYGSQAQSKLLNFSHDMINHVQKKDVGEIGEILGELMKKLEQVNPDDLQSKKKGFLARMFGRVSSSLQEVLSKYQKTSVQIDRISLKLEHSKNALISDNKLLEQLYEKNKEYFAALNVYIAAGELKLEELKTKTIPELKQQAESSDHNQMAVQEVNDLIQFADRLDKRVHDLLLSRQITIQSAPQIRLIQNTNQALAEKIQSSIVTAIPLWKNQVAIALTLLRQRNAVDAQQKVSDTTNELLLKNAELLKTNTIETARANERGLVDIDTLKKVQESLISTLEETLTIQEEGRIKRRQAEEELMMMEGDLKQKLITIKER
What are the official names of this protein?
Uncharacterized protein YaaN.
What is the protein family that this protein belongs to?
Belongs to the TelA family.
Protein: PIWIL_DUGJA
Sequence: MEIELIRKNLDGIRIERRGGLQKRFRIVEPDLQPNETKDKIGNVGKVVRLQSNFTKFSVNKSEKYIMYDTTFSKMGLSPKLKLQILVRICKEYNLPGSFCYDGRRLFTSDNWTEGSDIKEFTIDEKKVSLRLVSTFLSDTEEYYQMINVLLNNLQIIMGQEKIGKGYFLGSNSNKDNVVKNIGPTFFETNNFKVLGGFGTTLQRGTRPNGQLTTLLYIERINRVLNDNSVLVTYNRKNIDQLIGRDILTKYNNKTYRISEIKEMNINETFEMVGRTLSYAQYFKERYNINLTTEQQPFVLTRVKKIARRDKRKEHNENEAPEDMDLTLNITGELCFLCGFSDQEKSNIDLQKNLGCVLKRGPRERLDDIPSFCDWIKTNNNSQGMSNKWGLKIDNTPLEIEGRELPHCDVISGGQRINEKIKDDWKFGKVQFNVQKGVKHEIDVVIVDRNDSQYGNFLNDVEYEIKQLRFDAKIGRVLVCSANDVERSLNDVMRSGSGCAKIALVFVPDDRVYAKVKSFTISTGLLTQCVTTRNGTNRNDKRRQVVSSKTVMQIFSKFGYDPWTIDIKMRPTMIVGMDTFHNKGSKKSIHASVFSINSTFSQYMSFANSPKGKQEFHDTLSGNFKAALTEFKRIYKILPVRIMVYRDGVGDSQLQFTKQFEVDAMKPLVENIYKENGCQVPQIIYVIVKKRIGTKLFNRGDNANPGTIVDKEIVKPNFFEFFLVSQRVTRGTASPTNYNVLEDTRYQNKAGIIEAITPNELQRITYTLTHLYFNWMGTIRVPVPVHYAHKLAELIGKVHKGSTPALINERIRNRLFYL
What are the official names of this protein?
Piwi-like protein.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Piwi subfamily.
Protein: HMP_VIBVY
Sequence: MLSENTINIVKSTAPLLAETGPKLTAHFYQRMFEHNPELKDIFNMSNQRNGDQREALFNAICAYASNIDNLPALLGAVEKIAHKHSSFLITADQYQIVGSHLLATIDELFSPGQAVLDAWAEAYGVLANVFIQREEQIYQANQSQTGGWRGLREFELVEKQYESAHICSFVFKPVDGGSVVSFKPGQYLGIYINDEQFENQEIRQYSLSSSVRPDCYRISVKREEGGRVSNYLHDHLDVGSKVKLAAPAGDFFLDAAPTAPVVLISAGVGLTPTLSMLESLTEHQAPVTWIHATENGQQHAFKQHVKQLVETHPHFNSLVWYNQPNSDDKIGDDFQFSGWVNLHEIETVLKQADVQVYFCGPVGFMQFIAKQLLEMGVPEQQFHYECFGPHKVV
What is the function of this protein?
Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds.  Therefore, plays a central role in the inducible response to nitrosative stress.
What are the official names of this protein?
Flavohemoprotein, Flavohemoglobin, Hemoglobin-like protein, Nitric oxide dioxygenase, NO oxygenase, NOD.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: OTC_BUCAI
Sequence: MNNLYQRDCLRLLDFTSLELQNIITLAQKLKQYKKNNKEIQLLKKKNIALIFEKESTRTRCSFEVAAFDQGAHVTYLGPGSTHLGTKESIEDTAKILGRLYDGIQYRGHHHSTIEILAKNSKVPVWNGLTEKFHPTQLLADLLTIKEIFPERKFYEIKCAYVGDAHNNMGNSLLEAASLVGLDLRLVAPKECWPEKNIFKFCKEQMKNKKGNIICTENINEGVKNVDFIYTDVWVSMGESQEVWKKRIELLSSYQVNSLMLKITNNPQVKVLHCLPALHDQKTCTVKSILKKYGFKNGMEITDEVFQKNQKIIFEQAENRLHTIKAILVSSLLKTIKF
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETN_CYAM1
Sequence: MHLDLISITWGCLMATFTASLALVIWARNGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GSA_NOCFA
Sequence: MSASPRATHASAAASARLFDRAAQVIPGGVNSPVRAFRSVGGTPRFIASADGYTLTDADGNEYVDLVCSWGPMILGHAHPAVVDAVRRAATGGLSFGAPTEAEVELAEHIVARVAPVDRVRLVNSGTEATMSAVRLARGFTGRTKIIKFAGCYHGHVDALLADAGSGVATLGLPTSPGVTGAQAADTIVLPYNDLDAVAAAFEANPGEIACVITEAAAGNMGAVAPLPGFNAGLRELTENHGALLIMDEVMTGFRVSRSGWYGREGVAGDLYTFGKVMSGGLPAAAFGGRAEVMNQLAPLGPVYQAGTLSGNPVAVAAGLATLRAADDAVYAALDRNAERLGGLLTEALTAAGVEHQVQFAGNMVSVFFSDRPVTDYATAKASQTWRFPAFFHALLDGGVYAPPSAFEAWFVSAALDEDAFARIAAALPAAARAAAAATPEGSRA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_WOLTR
Sequence: MKPKHYPDTISSPDFSSLEKEIIKFWQENKIFEQSVEKRSKDNCFVFYDGPPFANGLPHYGHLLTGFIKDAFARYQTMLQKKVERRFGWDCHGLPAEMGAEKELGISGRTEIEKFGIEKFNNYCRTSVMKFSSEWEKYVNRQARWVDFHNDYKTMDRSFMESVIWAFKQLYDKGLVYESVRVVPYSWACETPLSNFETRLDTAYRKKTSKAVTVAFELLENPQQFKQKCKLLAWTTTPWTLPSNLALAIGKDIEYCAVSVHSSVSFQHVTLESREKETWIPLSRTGMTEEGTETVTEDNEVSLVNNEIYIFAEDYLEKFIGHCEQNNIPYENCNTKLKADDLAGLSYKPLFNYFKGTKNAFRVFIADYVTGEDGTGVVHTAPGFGEEDFYLCQSHDIPAICPIDNSGRFTAEVSDLTGIHVFDTNDAIIKKLKEQGNWFKTEQYIHNYPHCWRTDTPLIYRAMPSWYVAVTKFKERMIELNKRVNWIPTHIRDGQFGKWLERAHDWSISRNRFWGTPIPIWKSDNARYPRVDVYGSIAELERDFNVKVNDLHRPFIDSLTRPNPDDPTGKSIMRRVPDVFDCWFESGSVPFAQVHYPFENKEWFESNFPADFITEYIAQTRGWFYTLFVLSTALFDSEPFKNCICHGVVLDVKGQKLSKRLNNYADPMEVFDKYGSDALRFLMLSGSIVCGGNLFLNKEGSSIRDVLKNVMKPIWNSYHFFTMYANADGIKAEVCKDYKSTIDSYMIFKCFEAVESIQASMSNYNSQEACKILIDFFEVLNNWYIRRSRERFWKSNLDQDKTDAYNVLYTVFYYILRAAVPLLPLITETIWQGLKYKEISVHLADFPQLERYDSELIAKMDLVREICNSALSIRNTFNIRVRQPLGSMTVYHQSSCSFLESKPLSVVIPKFSPVIPMRDTGTQKEKKWSNAEMKTSMNEYQEMIKDEVNVKELKLVNSLEGIASLELKLNFPMLGKRIPDKVKKLVQYVKEGKWKQVDNEQVFLGNESESYIIEKDEYELLLKTNSEYSSVFGDNKGIVILNTALDDALVLEGLARDVVRLIQEARKQADFHISDRIRVIIKTEDEKIKRAINTWGEYIREQTLSLSLEINIEIGDNFYSKEYQDLIVGIELNC
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_ANADF
Sequence: MDKIVIDGGVPLRGSVATSGAKNAALPIIAGALLAEGDHLVRNVPDLADVRTLGRLLVHMGCQAERNAGEKGALWIRVPAAVQPEAPYELVKTMRASVVVLGPLVARWGKARVSLPGGCAIGARPIDQHLKGLSALGAEIRLEHGYVEATAPRGRLRGATFTFDAQTVTGTENVMMAAALAEGETLLRNCAREPEIVDLAAALVRMGARISGAGADEIRIEGVETLRPLDHVVIADRIEAGTFLAAGALPGNDVTVQGCVLEHVEALVEKLRAAGAEVLPVDGGLRVVGDGRPRPVDVRTAPHPGFPTDMQAQMMALLCLADGSSKITETVFENRFMHVQELQRLGAEIAVDGKTAVVKGVPELSGAPVMASDLRASAALVLAGLAAQGTTEVHRVYHLDRGYERIEEKLAPLGARIRREKA
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM6_PROM0
Sequence: MLKEPPKNSREKTKNLLLTLQDKICSGLENVDGKGKFTEESWLRDEGGGGRSRVLKNGSIFEQAGVNFSEVQGKELPQSIISQRPEAKGHEWFATGTSMVLHPKNPYIPTVHLNYRYFEAGPVWWFGGGADLTPFYPYLSDVRNFHNEHKKACEKVDQDLHKVFKPWCDEYFFLKHRNESRGIGGIFYDYQDGSGNIYRGNNQKGEASKASQNIGRSNLNWDDLFSLAENCGQAFLPSYLPIIEKRASQAYSSKEREFQLYRRGRYVEFNLVWDRGTIFGLQTNGRTESILMSLPPLARWEYGYKARKNSREEFLTSIFTKPQDWLNDKELEKFCIENNIFD
What is the function of this protein?
Involved in the heme and chlorophyll biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANMK_COXB2
Sequence: MPKERYIGLISGTSMDALDTALVQFDPLKIIATHGEPIPTELKKNLVALSTGTDNSIPSMGETDVALGRLFGEAVLTLLEKAKVSSDSIQAIGSHGQTIRHMPNGKHPFTLQIGDPNTIAALTGITTVADFRRRDMALGGQGAPLAPAFHEFLLRDQSENRLILNIGGIANLTFLPRDPEKSTIGFDTGPGNTLLDAWCLMNLNKDYDDQGQWAASGRVQEKLVAQLLAEPYFQTPPPKSTGREYFNLNWLKKNLNGEKFDPVDIQATLVELTARSVANCCRNFSMDSGSLWLCGGGARNHHLVNRLKVLCKPLRVTTTEEIGIHPDWLEAVCFAWLAKQTLEKKPGNLPSVTGAKKSAILGAIYWGEKFNY
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: KCNE1_PIG
Sequence: MALSNSTTVLPFLASLWQETDEPGGNMSADLARRSQLRDDSKLEALYILMVLGFFGFFTLGIMLSYIRSKKLEHSHDPFNVYIESDAWQEKGKALFQARVLESFRACYAIENQAAVEQPATHLPELKPLS
What is the function of this protein?
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits.  Modulates the gating kinetics and enhances stability of the channel complex.  Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1.  Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel.  The outward current reaches its steady state only after 50 seconds.  Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart (IKr).
What are the official names of this protein?
Potassium voltage-gated channel subfamily E member 1, Delayed rectifier potassium channel subunit IsK, IKs producing slow voltage-gated potassium channel subunit beta Mink, Minimal potassium channel.
What is the protein family that this protein belongs to?
Belongs to the potassium channel KCNE family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Apical cell membrane. Membrane raft. Note=Colocalizes with KCNB1 at the plasma membrane (By similarity). Targets to the membrane raft when associated with KCNQ1 (By similarity).
Protein: NUC_STAHY
Sequence: MKKITTGLIIVVAAIIVLSIQFMTESGPFKSAGLSNANEQTYKVIRVIDGDTIIVDKDGKQQNLRMIGVDTPETVKPNTPVQPYGKEASDFTKRHLTNQKVRLEYDKQEKDRYGRTLAYVWLGKEMFNEKLAKEGLARAKFYRPNYKYQERIEQAQKQAQKLKKNIWSN
What is the function of this protein?
Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5'-position of the phosphodiester bond.
What are the official names of this protein?
Thermonuclease, TNase, Micrococcal nuclease, Staphylococcal nuclease.
What is the protein family that this protein belongs to?
Belongs to the thermonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: SMO13_ARATH
Sequence: MIPYPTVEDASVALGRNLTWFETVWFDYSATKSNFHVYCHTILVLFLVFSLAPFPLVIVEWTGWFDQFKIQKKVKYSLSDMFQCYKEVMKLFLLVVGTLQIVSYPSIQMVGIRSGLPLPSLMEIVAQLVVYFLIEDYTNYWIHRWMHCKWGYEKIHRIHHEYTSPIGYASPYAHWAEILILGIPTFLGPAIAPGHIMTFWLWISLRQFEAIETHSGYDFPWSVTKLIPFYGGPEYHDYHHYVGGQSQSNFASVFTYCDYIYGTDKGYRIHKKLLHHQIKEEAEEKRVRKHD
What is the function of this protein?
Non-heme iron oxygenase involved in sterols biosynthesis by catalyzing the removal of the first methyl group at the C-4 position (By similarity).  4,4-dimethyl-9-beta,19-cyclopropylsterols such as 24-methylenecycloartanol are the preferred substrates (By similarity).
What are the official names of this protein?
Methylsterol monooxygenase 1-3, Sterol 4-alpha-methyl-oxidase 1-3, AtSMO1-3.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL13_PSEFS
Sequence: MTTFTAKPETVQRDWFVVDAAGQTLGRLATEVASRLRGKHKPEYTPHVDTGDYIVIINAEQVRVTGNKASDKMYYRHSGFPGGIKSSNFEGLIAKKPEAPIEIAVKGMLPKGPLGRDMFRKLKVYAGAVHPHAAQQPQELKF
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: GSTM2_MACFA
Sequence: MPMTLGYWNIRGLAHSIRLLLEYTGSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGTHKITQSNAILRYIARKHNLCGETEKEKIREDILENQLMDNRMQLARLCYDPDFEKLKPEYLEGLPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVWGNK
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.  Participates in the formation of novel hepoxilin regioisomers (By similarity).  Has activity toward aflatoxin B(1)-8,9-epoxide (AFBO) (PubMed:10869451).
What are the official names of this protein?
Glutathione S-transferase Mu 2, GST class-mu 2, GSTM2-2.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Mu family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLN5_HUMAN
Sequence: MAQEVDTAQGAEMRRGAGAARGRASWCWALALLWLAVVPGWSRVSGIPSRRHWPVPYKRFDFRPKPDPYCQAKYTFCPTGSPIPVMEGDDDIEVFRLQAPVWEFKYGDLLGHLKIMHDAIGFRSTLTGKNYTMEWYELFQLGNCTFPHLRPEMDAPFWCNQGAACFFEGIDDVHWKENGTLVQVATISGNMFNQMAKWVKQDNETGIYYETWNVKASPEKGAETWFDSYDCSKFVLRTFNKLAEFGAEFKNIETNYTRIFLYSGEPTYLGNETSVFGPTGNKTLGLAIKRFYYPFKPHLPTKEFLLSLLQIFDAVIVHKQFYLFYNFEYWFLPMKFPFIKITYEEIPLPIRNKTLSGL
What is the function of this protein?
Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane.  Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane (PubMed:22431521).
What are the official names of this protein?
Ceroid-lipofuscinosis neuronal protein 5, Protein CLN5.
What is the protein family that this protein belongs to?
Belongs to the CLN5 family.
What are the subcellular locations of this protein?
[Ceroid-lipofuscinosis neuronal protein 5, secreted form]: Lysosome. SUBCELLULAR LOCATION: [Ceroid-lipofuscinosis neuronal protein 5]: Membrane; Single-pass type II membrane protein. Note=An amphipathic anchor region facilitates its association with the membrane.
Protein: KR191_HUMAN
Sequence: MSHYGSYYGGLGYSCGGFGGLGYGYGCGCGSFCRRGSGCGYGGYGYGSGFGSYGYGSGFGGYGYGSGFGGYGYGCCRPSYNGGYGFSGFY
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 19-1, High tyrosine-glycine keratin-associated protein 19.1.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 19 family.
Protein: VKT31_CYRHA
Sequence: MGTARFLRAVLLLSVLLMVTFPALLSAEHHDGRVDICRLPSDSGDCLRFFEMWYFDGTTCTKFVYGGYGGNDNRFPTEKACVKRCAKA
What is the function of this protein?
Dual-function toxin that inhibits both serine proteases and voltage-gated potassium channels (Kv).
What are the official names of this protein?
U15-Kunitz-type theraphotoxin-Hhn1b, U15-TRTX-Hhn1b, Kunitz-type serine protease inhibitor HNTX-0314931.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. 03 (sub-Kunitz) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: END3_ASPCL
Sequence: MSTKKIEQWEIERYWEIFASLSNGQPHLNSSQAASVLRNSRLRDEQLEKVWDLADVDGDGELDFEEFCVAMRLVFDLVNGELQEVPRVLPDWLVPESKAHLVQAGRALSGRPEQFERIEDEDDTPGLKDGFDWYMNPADKSKYEEIYSANRNHRGEVTFESLQGLYDSLDVPDTDVRSAWNLVNPSASPAINKDATLAFLHILNYRHEGFRIPRTIPASLRASFENNKIDYQVDNARPAQKWGADGSTETLTGRKTKFGDTYLSRLGVGGKGSYTPKGTDFSDTIQDEEWEKVRLRRELAEMEAKLDAANKASEGRRDRPRNDGRPNWVLIKKEALQLLEYKERELRELREGTGRAKEGQDLERLRDDIKTVGDQVEGLKAHLAERKDVLADVRRQIEEERLHR
What is the function of this protein?
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis.  The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton.  Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins.  Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
What are the official names of this protein?
Actin cytoskeleton-regulatory complex protein end3, Cytoskeletal adapter protein sagA, Endocytosis protein 3.
What is the protein family that this protein belongs to?
Belongs to the END3 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, actin patch. Note=Cytoplasmic and cortical actin patches.
Protein: YF28_SCHPO
Sequence: MRRYLKKAKPKIVQTSDNEEEKHEENLNVSQSNKNANRRKTKAKEKNSGKFRVKYENEEGDDDGEDSQIPLIPKVKKQSSFHSVDDLISRRMDALSHESGYSNAYVDELKRKSRQTPSEFTKKEEDSSTKESELQTRSSPPLPVNTSLEWNMLNQGIPEEAMIKELKDREGRKRNIAMMTDNYISLETGDQLMLAQNHKEEKLLQTEDEIQDEGYSGFENYVEESEKLQEIYHHSSESLRTRSIQMAVDQKNMEMELDDEDIAEPIQSWEHTQIKKGAFGESPAFTNGLSVKLPNILTMDEQIQRLKEAIASEKLQQEERSQIIKSLMEEELEINEQEEKIKHSFIDLDKTLLNNLTKSKS
What are the official names of this protein?
Uncharacterized protein C17A2.08c.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CAGT_HELPJ
Sequence: MKLRASVLIGVAILCLILSACSNYAKKVVKQKNHVYTPVYNELIEKYSEIPLNDKLKDTPFMVQVKLPNYKDYLLDNKQVVLTFKLVHHSKKITLIGDANKILQYKNYFQANGARSDIDFYLQPTLNQKGVVMIASNYNDNPNNKEKPQTFDVLQGSQPMLGANTKNLHGYDVSGANNKQVINEVAREKAQLEKINQYYKTLLQDKEQEYTTRKNNQREILETLSNRAGYQMRQNVISSEIFKNGNLNMQAKEEEVREKLQEERENEYLRNQIRSLLSGK
What are the official names of this protein?
CAG pathogenicity island protein 12.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: TRI5_FUSCU
Sequence: MENFPTEYFLNTSVRLLEYIRYRDSNYTREERIENLHYAYNKAAHHFAQPRQQQMLKVDPKRLQASLQTIVGMVVYSWAKVSKECMADLSIHYTYTLVLDDSSDDPHPAMLNYFDDLQAGREQSHPWWALVNEHFPNVLRHFGPFCSLNLIRSTMDFFEGCWIEQYNFGGFPGSDDYPQFLRRMNGLGHCVGASLWPKDLFDERKNFLEITTAVAQMENWMVWVNDLMSFYKEFDDERDQISLVKNFVTCHEITLDEALEKLTQETLHSSKQMVAVFADKDPQVMDTIECFMHGYVTWHLCDARYRLHEIYEKVKDQDTEDAKKFCKFFEQAANVGAVAPSEWAYPQVAQLANVRAKDDMKEAQKPILSSIELVE
What is the function of this protein?
TS is a member of the terpene cyclase group of enzymes.  It catalyzes the isomerization and cyclization of farnesyl pyro-phosphate to form trichodiene, the first cyclic intermediate in the biosynthetic pathway for trichothecenes.  It serves to branch trichothecene biosynthesis from the isoprenoid pathway.
What are the official names of this protein?
Trichodiene synthase, Sesquiterpene cyclase, TS.
What is the protein family that this protein belongs to?
Belongs to the trichodiene synthase family.
Protein: PAGP_SHIFL
Sequence: MNVSKYVAIFSFVFIQLISVGKVFANADERMTTFRENIAQTWQQPEHYDLYIPAITWHARFAYDKEKTDRYNERPWGGGFGLSRWDEKGNWHGLYAMAFKDSWNKWEPIAGYGWESTWRPLADENFHLGLGFTAGVTARDNWNYIPLPVLLPLASVGYGPVTFQMTYIPGTYNNGNVYFAWMRFQF
What is the function of this protein?
Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors.
What are the official names of this protein?
Lipid A acyltransferase PagP, Lipid A acylation protein.
What is the protein family that this protein belongs to?
Belongs to the lipid A palmitoyltransferase family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RS8_LISW6
Sequence: MVMTDPIADFLTRIRNANMVKHDKLELPASKIKKEIAEILKREGFIRDVEYIEDDNAGTIRVFLKYGATGERVITGLKRISKPGLRVYAKSTEVPKVLNGLGIAIVSTSQGVLTDKEARAKQVGGEVLAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: VA546_SCODE
Sequence: NILLSSTLFVLLMFQIIGSGLGCDMKVRGLDANMKKMILDLPNKKRQIVANGQQSGQPSAPNMKELHWNDEIAANAQRSGETGVFEPTAKSLRKTTKYSYLGENIYKGFYPDPIPKSVNGWYEEVKDVPPAVVKSFSSGGPMFGHYTQMVWANTEPLGCGLVTAFDRNSYLFCQYDPGGNYRSHPIYKQGPPASDCKNGKSSKYPGLCN
What is the function of this protein?
May act as a voltage-gated calcium channel inhibitor.
What are the official names of this protein?
Scoloptoxin SSD346, Cysteine-rich venom protein, CRVP.
What is the protein family that this protein belongs to?
Belongs to the CRISP family. Venom allergen 5-like subfamily.
What are the subcellular locations of this protein?
Secreted.