PharMolix/UniProtQA huggingface dataset:
Protein: IF3_RIPO1
Sequence: MIDKRRPQRDLPKINERIRFPEIRVIDSDGSQVGVITPKEALSLAQEKELDLVLVSETAKPPVCRIMDYGKYKFEQEKKAREAKKKQHTADVKEVKMRYKIGESDYNVRVNQAKRFLKSGDKVKATVTFRGREIQHANLAQELLERMAKDLEELAEIQQAPKREGRNMMMFLTPKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_STAAC
Sequence: MSDRIRVRYAPSPTGYLHIGNARTALFNYLYAKHYNGDFVIRIEDTDKKRNLEDGETSQFDNLKWLGLDWDESVDKDNGYGPYRQSERQHIYQPLIDQLLAEDKAYKCYMTEEELEAEREAQIARGEMPRYGGQHAHLTEEQRQQFEAEGRQPSIRFRVPQNQTYSFDDMVKGNISFDSNGIGDWVIVKKDGIPTYNFAVAIDDHYMQISDVIRGDDHISNTPKQIMIYEAFGWEPPRFGHMSLIVNEERKKLSKRDGQILQFIEQYRDLGYLPEALFNFIALLGWSPEGEEEIFSKEEFIKIFDEKRLSKSPAFFDKQKLAWVNNQYMKQKDTETVFQLALPHLIKANLIPEVPSEEDLSWGRKLIALYQKEMSYAGEIVPLSEMFFKEMPALGEEEQQVINGKQVPELMTHLFSKLEALEPFESAEIKKTIKEVQKETGIKGKQLFMPIRVAVTGQMHGPELPNTIEVLGKEKVLNRLKQYK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNCB_DANRE
Sequence: MATSNEAGSVLNRVPPLLTDLYQMAYAYWRAGRHNEPAVFELFFRDNPFGGGFSLFAGLSDCLLFLQNFSFSDDDVQYLRSVLPADTDAGFFSYLKELDCSCVSVSAVPEGSVVFARVPLLEVSGPLAVVQLLETSLLCLVNYASLVCSNAARFRLAAGPRRRLMEMGLRRAQGPDGGLTASRYTYIGGFDLTSNALAGRLYGIPVAGTMAHSYITSFSSLEEVWPQTLKPCGGGDSIDFICLVKGLLGRVCQLLGSKTNLIREGELAAFLSYAIAYPQNFLPVIDSYSVRCSGLLCFCAVALALFELQYRPLGVRLDSGDLCRQSLDVRRVFRECSKHFSVPQFESLIIVGTNSISEQSLSELNKKDNEIDVVGVGTHLVTCTRQPSLGCVYKLVEVRGRPRMKLSEDPEKSTLPGRKAVYRLLDADGHPQMDVLCLCDEAAPAAGVELQCFSLLGNSTLQCSITPAQVSSLRTQVFSCGQITLPLNSASESRERAQISLQMLNPYHKRLQEPHNYTVALSERLHSLVSDIKKGNSKGSNFLLSN
What is the function of this protein?
Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.  Helps prevent cellular oxidative stress via its role in NAD biosynthesis.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase, Nicotinate phosphoribosyltransferase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: Y9488_RHOBA
Sequence: MNSNTPSSDNSSPDNVSPDTSDMASAGDDSALATPPPRPSLWKDMTTNEDWWAIWCAALLLLIAFAAVWIGQPENLSELIAGSTMEEVSQVETAPENAGPSAEAENEAIETENTAPAENADLEVAETQEVAEEEPYEYASPLKPFLAKPGKWTANPLDAISSSWSGILGVFLIIAALFAFANQMRGKSAGAFLAAFPVIFLLATLAYWMSGQSVVKAYNLEYALWALLVGLIISNTVGTPDFLRPAISTEFYIKTGLVLLGAEVLMSRLLALGLPGVFVAWLVTPVVLITTYWFGQKVLKIQSKSLNMVISADMSVCGVSAAIATAAACKAKKEELSLSIGLSLGFTVIMMAVMPAVITAMGIDPILGGAWLGGTIDSTGAVAAAGAVLGDEALEVAATVKMIQNILIGVTAFCVAIYWVTFVERDPAGPRIGISEIWYRFPKFVLGFVSMSILFSILYSYMTNGPELINAMIGGSTKTLRGWFFCLAFVSIGLETNFRQLLPQLKGGKPLVLYVCGQSLNLVLTLVMAYLMFKVVFADTVAP
What are the official names of this protein?
UPF0324 membrane protein RB9488.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VLP12_BORHE
Sequence: MRKRISAIIMTLFMVLASCSNQLEAEKLAAESKNTFFDSLVKIGQGFQDIFGIFGNAIGDALGFNAVKSDDKRSKVGEHFEGVGKGLKDTKIKLDELLKEVTAAPHADTTEVKSVINSASAVLTKLIDSVTKLAGAVGNTDIADGVSIANGAAAEEASVKTVIEGVKEIIDVATNSGVKIEKGNAGTAVANANGPKAIIHNAQAAAGDATKLADEVAKADPWAMIDKIKNAKTKNGIAAANDDAGQLATATNAANNNGTAATNADLAAAVALKAMAKGGKFTQPAANEDGAVKAAAASAVNKVLGILDVIIRKAVNLELGKIKEAVKGIKYSEATGEATESDTAQPITNKSSN
What is the function of this protein?
The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time.  Switching between these genes is a mechanism of host immune response evasion.
What are the official names of this protein?
Variable large protein 12.
What is the protein family that this protein belongs to?
Belongs to the variable large protein (Vlp) family. Beta subfamily.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: YLIM_ECOLI
Sequence: METFCYMKWPVRHHKSRRVSH
What are the official names of this protein?
Protein YliM.
Protein: MUC1_XENLA
Sequence: APTTAAAVAATGKDTTAAAEGSAAAEKTAAAGEVSAPPTAAVAATGEDATTAAATAAAETTAAAGEAPTTTTAPATTAAGKAPTTAAATAPTTAAAGAPTTATGKAPATAAAPVPTTAASKAPTTAAAATHSTAAAAAPTTAASAAKSKERSTSSSSEEEHCHVKPSKREMCGSKGITKKQCKKKNCCFDPKGHGGIHCFHRKPKGHSHEEHTTTTTKAPTTIQIATTTTTPTTTTTTTKATPTTTTTTKATPTTTTTTKATTTTTTPTTTTTTTKATTTPTTTTTTTPTTTTTKATTTTTTTSGECKMEPSKREDCGYSGITESQCRTKGCCFDSSIPQTKWCFYTLSQVADCKVEPSQRVDCGFRGITADQCRQKNCCFDSSISGTKWCFYSTSQVAATKTTTTPTTTTTPTTTTTTKATTTTPTTTTTTPTTTTTTTTTTKATTTTPTTTTPTTTTTKATTTTPTTTTTTPTTTTTKATTTTPTTTTTTPTTTTTKATTTTPTTTTTTTTTTKATTTTTSGECKMEPSKRADCGYPGITESQCRSKGCCFDSSIPQTKWCFYSLPQVADCKVAPSSRVDCGFGGITADQCRQRNCCFDSSISGTKWCFYSTSQGNAMCSGPPTKRRDCGYPGISSSVCINRGCCWDNSVMNVPWCFYRT
What is the function of this protein?
Could be involved in defense against microbial infections.  Protects the epithelia from external environment.
What are the official names of this protein?
Integumentary mucin C.1, FIM-C.1.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPA_RICRS
Sequence: MKLKPIEVAEILQKEIANINCLSELEEVGQVITVGDGIAQIYGLANVKSGEVVEFKSGVKGLVLNLENDSVGVVIMGDDNQVQQGDNVKRTKEVLEVPVGKALLGRVVDALGNPIDGKGDIASKEYRHIEMKAPGIIERTSVSEPVQTGIKAIDSLIPIGRGQRELIIGDRQTGKTAIAVDTIINQKQAHSLTNESDKIYCIYVAIGQKRSSVAQIVKKLEDAGAMDYTLIVSATASEAAALQFIAPYSACSMGEYFRDNGMHALIIYDDLSKHAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAKMSEEKGSGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLESELFYKGVRPAVNVGISVSRVGSAAQIKAMKQVAGSVKLELAQFRELESFSQFGSDLDPATKAQIDHGKRLVEILKQAQYNPFPVEEQIVSIYVGTKKYLNDVPLQKVKEFEDKMLTEIRLNKKDILESIKNEQCITEETEQKLKAFLENFVKEFVK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PROAT_OLEEU
Sequence: MSWQAYVDDHLKCDIEGHEGHRLTAAAIVGHDSSVWAQSATFPQFKPEEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVFGIYEEPVTPGQCNMVVERLGDYLLEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-2, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: SYS_RALPJ
Sequence: MLDIQLLRKDIDAVAARLKDRGYVLDVAGFAALEAERKAIQTRTEELQARRNSLSKQIGVLKGKGEDASGVMAEVSGIGDELKASAAQLDVVQAKLQDLMLSIPNLPHESVPAGRDETQNVEVRREGTPRTFDFPVKDHVDLGAALGLDFDAGAKLSGARFTVLKGQVARLHRALAQFMLDTHTLEHGYTEAYVPYIVNAASMRGTGQLPKFEEDLFRVPRKMGHSAEEGDGERVENFYLIPTAEVPLTNLVRDEIVAADTLPMMFAAHSPCFRSEAGSYGKDTRGMIRQHQFDKVEMVQIVQPETSAAALEAMTNCAENILRKLELPFRTVVLCTGDMGFGSTKTYDIEVWIPAQNTYREISSCSNMGDFQARRMQARFRNAQGKPELVHTLNGSGLAVGRTLVALLENYQNADGSVTVPTALRPYLGGQEVLKPAV
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DP71L_ASFB7
Sequence: MGGRRRKKRTNDTKHVRFAAAVEVWEADDIERKGPWEQVAVDRFRFQRRIASVEELLSTVLLRQKKLLEQQ
What is the function of this protein?
Interacts with the host phosphatase PP1 catalytic subunit (PPP1CB) and recruits it to dephosphorylate EIF2S1/eIF2alpha and therefore restores the host translation that has been shut-down by the host.  Also inhibits the EIF2S1/eIF2alpha-ATF4-DDIT3/CHOP pathway.
What are the official names of this protein?
Protein DP71L, MyD116 homolog.
What is the protein family that this protein belongs to?
Belongs to the asfivirus DP71L family.
Protein: MNMA_LIGS1
Sequence: MKDKSQIRVVVGMSGGVDSSVSAYLLKQQGYDVVGVFMKNWDDKNDSGVCTVTEDYQDVAKVASQIGIPYYSVNFEKEYWDRVFTYFLDEYKNGRTPNPDIMCNKEVKFKAFLDYAMSIDADYIAMGHYAQLRRDEDGRVHLLRGADDNKDQTYFLSQLSQEQLQKVMFPIGHLQKSEVRRIAEEAGLATAKKKDSTGICFIGERNFSKFLGEFLPAQPGEMVTLDGEVKGNHFGLMNYTIGQRKGLGIGGDGKSNEPWFVIGKDLKTNTLLVGQGYHNEHLYANSLDASKLSFVDDISDCGDEFHCTAKFRYRQKDTGVTVKFNEDRTKVEVIFDEPVRAITPGQEVVFYDGEECLGSGTIDHAYKESKLLQYV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAF_BOVIN
Sequence: MTTSQKHRDFVAEPMGEKPVGSLAGIGEVLGKKLEERGFDKAYVVLGQFLVLKKDEDLFREWLKDTCGANAKQSRDCFGCLREWCDAFL
What is the function of this protein?
Non-specific DNA-binding protein that plays key roles in mitotic nuclear reassembly, chromatin organization, DNA damage response, gene expression and intrinsic immunity against foreign DNA.  Contains two non-specific double-stranded DNA (dsDNA)-binding sites which promote DNA cross-bridging.  Plays a key role in nuclear membrane reformation at the end of mitosis by driving formation of a single nucleus in a spindle-independent manner.  Transiently cross-bridges anaphase chromosomes via its ability to bridge distant DNA sites, leading to the formation of a dense chromatin network at the chromosome ensemble surface that limits membranes to the surface.  Also acts as a negative regulator of innate immune activation by restricting CGAS activity toward self-DNA upon acute loss of nuclear membrane integrity.  Outcompetes CGAS for DNA-binding, thereby preventing CGAS activation and subsequent damaging autoinflammatory responses.  Also involved in DNA damage response: interacts with PARP1 in response to oxidative stress, thereby inhibiting the ADP-ribosyltransferase activity of PARP1.  Involved in the recognition of exogenous dsDNA in the cytosol: associates with exogenous dsDNA immediately after its appearance in the cytosol at endosome breakdown and is required to avoid autophagy.  In case of poxvirus infection, has an antiviral activity by blocking viral DNA replication.
What are the official names of this protein?
Barrier-to-autointegration factor.
What is the protein family that this protein belongs to?
Belongs to the BAF family.
Protein: AP1_YEAST
Sequence: MSVSTAKRSLDVVSPGSLAEFEGSKSRHDEIENEHRRTGTRDGEDSEQPKKKGSKTSKKQDLDPETKQKRTAQNRAAQRAFRERKERKMKELEKKVQSLESIQQQNEVEATFLRDQLITLVNELKKYRPETRNDSKVLEYLARRDPNLHFSKNNVNHSNSEPIDTPNDDIQENVKQKMNFTFQYPLDNDNDNDNSKNVGKQLPSPNDPSHSAPMPINQTQKKLSDATDSSSATLDSLSNSNDVLNNTPNSSTSMDWLDNVIYTNRFVSGDDGSNSKTKNLDSNMFSNDFNFENQFDEQVSEFCSKMNQVCGTRQCPIPKKPISALDKEVFASSSILSSNSPALTNTWESHSNITDNTPANVIATDATKYENSFSGFGRLGFDMSANHYVVNDNSTGSTDSTGSTGNKNKKNNNNSDDVLPFISESPFDMNQVTNFFSPGSTGIGNNAASNTNPSLLQSSKEDIPFINANLAFPDDNSTNIQLQPFSESQSQNKFDYDMFFRDSSKEGNNLFGEFLEDDDDDKKAANMSDDESSLIKNQLINEEPELPKQYLQSVPGNESEISQKNGSSLQNADKINNGNDNDNDNDVVPSKEGSLLRCSEIWDRITTHPKYSDIDVDGLCSELMAKAKCSERGVVINAEDVQLALNKHMN
What is the function of this protein?
Transcription activator involved in oxidative stress response and redox homeostasis.  Regulates the transcription of genes encoding antioxidant enzymes and components of the cellular thiol-reducing pathways, including the thioredoxin system (TRX2, TRR1), the glutaredoxin system (GSH1, GLR1), superoxide dismutase (SOD1, SOD2), glutathione peroxidase (GPX2), and thiol-specific peroxidases (TSA1, AHP1).  The induction of some of these genes requires the cooperative action of both, YAP1 and SKN7.  Preferentially binds to promoters with the core binding site 5'-TTA[CG]TAA-3'.  Activity of the transcription factor is controlled through oxidation of specific cysteine residues resulting in the alteration of its subcellular location.  Oxidative stress (as well as carbon stress, but not increased temperature, acidic pH, or ionic stress) induces nuclear accumulation and as a result YAP1 transcriptional activity.  Activation by hydrogen peroxide or thiol-reactive chemicals elicit distinct adaptive gene responses.  Nuclear export is restored when disulfide bonds are reduced by thioredoxin (TRX2), whose expression is controlled by YAP1, providing a mechanism for negative autoregulation.  When overexpressed, YAP1 confers pleiotropic drug-resistance and increases cellular tolerance to cadmium, iron chelators and zinc.
What are the official names of this protein?
AP-1-like transcription factor YAP1, Phenanthroline resistance protein PAR1, Pleiotropic drug resistance protein PDR4.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. YAP subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Oxidized YAP1 is found predominantly in the nucleus, while reduced YAP1 is continuously exported to the cytoplasm by CRM1/exportin 1. Nuclear import requires the karyopherin PSE1/KAP121 and is independent on YAP1 oxidation state.
Protein: YANE_ASPNA
Sequence: MAPCKPRTFTAGEDPLTKFDGAISVATMPRPADRQFLFHGIMRPSRGIYAKLVATGKKPPTHFHPSQWEFFRVLRGNLTVDINGVPVHRTVDDGEMAVPPYTHHVIYGTPGTEMNEVEFLVSATDEEEGATAMDQEFFENWYGYQEDIFQRGEKIDLIQVLAMFDAGGTYLSPPWWVPFRAWVGLILGIVIGRWIGGLLGYAPFYPEWTTNWDAACDRMEQSWFQRRYADRGAQQRAREKFQVQKGQGTVAKGEKSE
What is the function of this protein?
Part of the gene cluster that mediates the biosynthesis of yanuthone D, a fungal isoprenoid epoxycyclohexenone that acts as an antibiotic against fungi and bacteria (PubMed:24684908).  The first step of the pathway is the synthesis of 6-methylsalicylic acid (6-MSA) by the polyketide synthase yanA (PubMed:24684908).  6-MSA is then converted to m-cresol by the decarboxylase yanB (PubMed:24684908).  The cytochrome P450 monooxygenase yanC then catalyzes the oxidation of m-cresol to toluquinol (PubMed:24684908).  Epoxidation of toluquinol is then performed by the short chain dehydrogenase yanD, with the help of yanE, and a further prenylation by yanG leads to 7-deacetoxyyanuthone A (PubMed:24684908).  The next step is the hydroxylation of C-22 of 7-deacetoxyyanuthone A by the cytochrome P450 monooxygenase yanH to yield 22-deacetylyanuthone A (PubMed:24684908).  O-Mevalon transferase yanI then attaches mevalon to the hydroxyl group of 22-deacetylyanuthone A to produce yanuthone E (PubMed:24684908).  Finally, the FAD-dependent monooxygenase yanF oxidizes the hydroxyl group at C15 of yanuthone E to form yanuthone D (PubMed:24684908).  Furthermore, several branching points in the pathway lead to the production of yanuthones F and G from 7-deacetoxyyanuthone A; yanuthones H and I from 22-deacetylyanuthone A; and yanuthone J from yanuthone E (PubMed:24684908).  YanE is also involved in the synthesis of yanuthone X1 which does not have 6-methylsalicylic acid (6-MSA) as precursor (PubMed:24684908).
What are the official names of this protein?
Probable oxidoreductase yanE, Yanuthone D biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the oxidoreductase OpS7 family.
Protein: HEM1_PROM9
Sequence: MHIVVVGLSHRTAPVEVREKLSIPDQSITKSLKALKAFSEVLEVSILSTCNRLEIYALVKDKNTGISSIKEFISDYSGIIFEDLNPHLFCFRQEDAVLHLMKVSAGLDSLVLGEGQILSQVKKMMRLGQENQSTGPILNRLLTQSVSTGKKVRSETNLGTGAVSISSAAVELAQLKIGQEKGFDTLVSLESEKVLVVGAGRMSRLLITHLKAKGCHKLILVNRNIDRALNLAIDFPDIEIVCKGLNELDENISISSLVFTSTASEEPIIDLAKIEKLNLNNKLKFIDIGVPRNISNDVKNHQFVKSFDVDDLQEVVSRNQEFRQKIAKEAESLVEEERIIFLEWWASLEAVPVINKLRSDLELIRKEELQKALSRMGPDFSARERKVVEALTKGIINKILHTPVTKLRSPQSREERQASLKIVEKLFSLVDEDKNS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: CYSH_SALAR
Sequence: MSVLDLNALNDLPKVDRVLALAETNAELEKLVAEERVAWSLENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDALTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNEINKVEPMNRALQDLNAQTWFAGLRREQSGSRTSLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWHQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBK9_ENCCU
Sequence: MMRTWMVYVVGLVGELYGSQVEETREMREMKEALERLFSRRLSDSEIEMVESLENGGNFETRVLVPVIFHKDKVVVSPAARYRDIEKEERVYVEEVIRRLRSLVWHSMVYIYVPKNNDWIMDLICKVSGMSSPQRLDDVALYKDTGGNCGMKFVDLVNKMFKQNADMLKKFGDLLSNGAETRILELPDSLSEDERRREVEMLQRVKEYGKMLCTEDKQKEIVEAQKIMCDACEQIWRREEDRKEFTMEIYSRYLNMKVMRGGVERDVEDPLIDHMDHYMLISTHKKYKCMDVVAELVRKVFVEDKDIEDSDVMSAVCSVRERKRLEEMREMEERKRKEEERAKNEEELLRMVEREEREKREESKGRGKKKRGNRGAGESKEESKGRGKRKRGNKGAGESKEEDRGEEGGVEAEDPLEEMAVGEAWRKKKGSGEKRISEEHHYKVHSRVLRWKKDAGEIKRELDEGYEKKWKNRSIEEIKEQKKVHDIVEVMKLLRDKEKCDRFFVRTGKYMKGKSERWKMVANGILEEGGEKKVGKVEVGLFKGEGGESVVYHLMFRPTETERTGRVGGSSFGKYDDVDEIKKEKSSDMFGFRYPSGVRCEMTSNRNEFRIEYRNRKNTSEVLRTLTILRIPET
What are the official names of this protein?
UPF0329 protein ECU11_2090.
What is the protein family that this protein belongs to?
Belongs to the UPF0329 family.
Protein: MT3_CARPA
Sequence: MSDTCGNCDCADKTQCVKKGSSYTADIIETEKSIMTVVMDAPAAENDGKCKCGPSCSCTNCTCGH
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein-like protein type 3, MT-3.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 15 family.
Protein: COQ41_CULQU
Sequence: MFLRRVHPVRLGHASQRSLTTTKSRNESTTTTVEAPQAAPSPPPDAFTEEFLRNQIKVTELQRVILGVGSSLAALVNPRRHDMIACLGETTGVPALDAIRRQMLASDEGRQILADRPRINTRTVDMAALKALPETSFGHQYVHFLEKHDITPDSRAEVRFMDDPELAYVMTRYREVHDLVHTVLGMPTNMLGEVAVKWVEALNTGLPMCYGGAVFGAQRQNYLRHYLPWALRMGRQVRPLMNVYWEKRWEQDMAELRQELNIEELVIN
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ4 homolog 1, mitochondrial, Coenzyme Q biosynthesis protein 4 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: MPL_MPLV
Sequence: LELRPRARYSLQLRARLNGPTYQGPWSAWSPPARVSTGSETAWITLVTALLLVLSLSALLGLLLLKWQFPAHYRRLRHALWPSLPDLHRVLGQYLRDTAALSPSKATVTDSCEEVEPSLLEILPKSSESTPLPLCPSQPQMDYRGLQPCLRTMPLSVCPPMAETGSCCTTHIANHSYLPLSYWQ
What is the function of this protein?
Truncated form of the receptor for thrombopoietin.
What are the official names of this protein?
Myeloproliferative leukemia protein.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 1 subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: APN_DROME
Sequence: MAANQKIVFALVCLFLACDLVLGQQQAANSSDSDSDVAESRTFGHHFLRRISFALVPGAFVVGVITTLLAALTVVSIKGLGVGVILLVLAIGQMLSRALPVQAAAAYAAAPVPVQAPVPVVYSHSHTQQPVWLEKEW
What is the function of this protein?
Transmembrane protein that plays a key role in trachea development by regulating crb localization and maintenance at the apical cell membrane (PubMed:30645584).  Required for anisotropic apical surface expansion important for tracheal tube elongation and lumen stability at larval stages (PubMed:30645584).
What are the official names of this protein?
Protein apnoia.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Note=In tracheal cells, colocalizes with crb in the subapical region, a small region of the apical membrane apical to the adherens junctions.
Protein: YBCC_RHOCA
Sequence: MDLLFDEFRAAHVPVEEMATHYIPEAARQIGAAWDSDRIGFAQVTIAISRLQELLHALQTLVTADSVGCANGATVLLIVPPGEQHTLGALIVAMELRRRGVSVRIVFAPGLSDLSRLMATTRFDAALITVGSMDRVEICAKLVKTLSSLTKGRMRVAIGGAIVSQRAEALARTGADLVTNDLSLVISEFSLV
What are the official names of this protein?
Uncharacterized 20.5 kDa protein in bchF-crtJ intergenic region, ORF192.
Protein: MNME_MANSM
Sequence: MMTKETIVAQATPIGRGGVGILRVSGPLATEVAKAVVDKELKPRMANYLPFKDEDGTILDQGIALYFKSPNSFTGEDVVEFQGHGGQVVLDLLLKRILQVKGVRLARPGEFSEQAFLNDKLDLAQAEAIADLINASSEQAARSALKSLQGEFSKKINQLVDSVIYLRTYVEAAIDFPDEEIDFLADGKIEGHLNDLIGQLDKVRSEAKQGSILREGMKVVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLRDATDEVERIGITRAWNEIEQADRVILMLDSTDPDSKDLDQAKAEFLSKLPGNIPVTIVRNKSDLSGEKESIEEQEGFTVIRLSAQTQQGVSLLREHLKQSMGYQTGTEGGFLARRRHLEALEHAAEHLQIGRVQLTQFHAGELLAEELRIVQDYLGEITGKFTSDDLLGNIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOCD_PSEFS
Sequence: MTTGSALYIPPYKADDQDVVVELNNRFGPDAFTAQATRTGMPVLWVARAKLVEVLTFLRNLPKPYVMLYDLHGVDERLRTKRQGLPSGADFTVFYHLLSIERNSDVMIKVALSESDLSVPTVTGIWPNASWYEREVWDMFGIDFPGHPHLTRIMMPPTWEGHPLRKDFPARATEFDPFSLNLAKQQLEEEAARFRPEDWGMKRSGTNEDYMFLNLGPNHPSAHGAFRIILQLDGEEIVDCVPDIGYHHRGAEKMAERQSWHSFIPYTDRIDYLGGVMNNLPYVLSVEKLAGIKVPDRVDTIRIMMAEFFRITSHLLFLGTYIQDVGAMTPVFFTFTDRQRAYKVIEAITGFRLHPAWYRIGGVAHDLPNGWERLVKEFIDWMPKRLDEYQKAALDNSILKGRTIGVAAYNTKEALEWGVTGAGLRSTGCDFDLRKARPYSGYENFEFEVPLAANGDAYDRCIVRVEEMRQSLKIIEQCMRNMPAGPYKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGGTMSYRTRIRTPSFPHLQQIPSVIKGEMVADLIAYLGSIDFVMADVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.