Coxsackie virus

# Overview
Coxsackie (virus) is a cytolytic virus of the picornaviridae family, an enterovirus (a group containing the polioviruses, coxsackieviruses, and echoviruses). There are 61 non-polio enteroviruses that can cause disease in humans, of which 23 are coxsackie A viruses (6 are Coxsackie B viruses). Enterovirus are the second most common viral infectious agents in humans (after the rhinoviruses)

# Classification
Coxsackie viruses consist of coxsackie A virus and coxsackie B virus. Coxsackie B virus has 6 serotypes, one of the significant serotypes is called coxsackie B4 virus.

# Differential Diagnosis
Coxsackie A virus and coxsackie B virus can cause multiple diseases in humans. The wide array of diseases caused by coxsackie viruses can be differentiated from one another easily on the basis of involvement of the organs systems, clinical presentation and diagnostic techniques.
Coxsackie virus oral lesions must be differentiated from other mouth lesions such as oral candidiasis and aphthous ulcer

## Oral Involvement
Oral lesions of coxackie virus infection must be differentiated from other diseases causing oral lesions such as leukoplakia and herpes simplex virus infection.
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