Pallor

# Overview
Pallor is a reduced amount of oxyhemoglobin in skin or mucous membrane, a pale color which can be caused by illness, emotional shock or stress, avoiding excessive exposure to sunlight, anaemia or genetics. It is more evident on the face and palms. It can develop suddenly or gradually, depending on the cause.
Pallor is not usually clinically significant unless it is accompanied by a general pallor (pale lips, tongue, palms, mouth and other regions with mucous membranes). It is distinguished from similar symptoms such as hypopigmentation (loss of skin pigment).
Pale skin is also a very light skin tone most commonly associated with people of European descent, particularly people of Celtic and Scandinavian descent. In addition, people who avoid excessive sun exposure and thus avoid unhealthy sun tanning also tend to have paler complexions in comparison to their peers, particularly during summer.

# Physical examination findings of pallor and paleness
- White fingers
- White Nails
- White patches or blotches
- Hypopigmentation

# Causes

## Common Causes

## Causes by Organ System

## Causes in Alphabetical Order
- Abdominal aneurysm
- Abdominal cancer
- Acanthocytosis
- Achrestic anemia
- Acne-sol powder
- Acquired aplastic anemia
- Acquired idiopathic sideroblastic anemia
- Acquired prothrombin complex deficiency
- Acquired pure red cell aplasia
- Acquired aplastic anemia
- Acquired prothrombin complex deficiency
- Acromegaly
- Actinic cheilitis
- Acute arterial occlusion
- Acute biphenotypic leukemia
- Acute blood disorder
- Acute cholinergic dysautonomia
- Acute erythroleukemia
- Acute leukemia
- Acute megacaryoblastic leukemia
- Acute meningitis
- Acute myeloblastic leukemia
- Acute myelocytic leukemia
- Acute myelofibrosis
- Acute myeloid leukemia
- Acute non lymphoblastic leukemia
- Acute panmyelosis
- Acute tubulointerstitial nephritis
- Acute cholinergic dysautonomia
- Acute interstitial nephritis
- Acute myelofibrosis
- Adenosine triphosphatase deficiency
- Adrenal adenoma
- Adrenal cancer
- Adrenal gland hyperfunction
- Adrenal hemorrhage
- Adrenal hypertension
- Adrenal incidentaloma
- Adrenal medulla neoplasm
- Albinism
- Albinism deafness syndrome
- Alcohol-induced hypertension
- Aldicarb
- All-down syndrome
- Allergic tension-fatigue syndrome
- Alpha thalassemia
- Alpine syndrome
- Amphetamine abuse
- Anaphylaxis
- Anemia
- Anisocytosis
- Aortic arches defect
- Aortic dilatation
- Aplastic anemia
- Apnea
- Arrhythmia
- Asrar-facharzt-haque syndrome
- Athlete's foot
- Autoimmune hemolytic anemia
- Autoimmune thyroid disease
- Azotemia
- Back tumor
- Bacterial meningitis
- Banti's syndrome
- Basilar migraine
- Benacine
- Benign paroxysmal torticollis of infancy
- Beractant
- Beta thalassemia
- Bitolterol
- Black locust poisoning
- Bland-garland-white syndrome
- Blue diaper syndrome
- Bone marrow failure syndromes
- Bromophos
- Brompheniramine
- Calcium deficiency
- Carbaryl
- Cardiac tamponade
- Catovit
- Celiac disease
- Cephalosporin-induced immune hemolytic anemia
- Cerebelloparenchymal autosomal recessive disorder 3
- Chediak-higashi syndrome
- Chloramphenicol-induced sideroblastic anemia
- Chlorate salts
- Chlorfenvinphos
- Chlorpyrifos
- Chronic anemia
- Chronic arterial occlusive disease
- Chronic kidney disease
- Chronic leukemia
- Chronic myelogenous leukemia
- Chronic myeloid leukemia
- Chronic myelomonocytic leukemia
- Chronic orthostatic hypotension
- Cidofovir
- Ciliary dyskinesia-bronchiectasis
- Clotting disorder
- Cobalamin malabsorption
- Cocaine-induced hypertension
- Cold autoimmune hemolytic anemia
- Collagenous celiac disease
- Compartment syndrome
- Complete atrioventricular canal
- Congenital aplastic anemia
- Congenital arteriovenous shunt
- Congenital deficiency of intrinsic factor
- Congenital herpes simplex
- Congenital hypothyroidism
- Congenital spherocytic anemia
- Congenital vitamin b12 malabsorption
- Congenital aplastic anemia
- Congenital spherocytic hemolytic anemia
- Conn syndrome-induced hypertension
- Cooley syndrome
- Copper deficiency-induced sideroblastic anemia
- Corticosteroid-induced hypertension
- Coumaphos
- Cowden's syndrome
- Cushing's syndrome-induced hypertension
- Cyclic vomiting syndrome
- Cycloserine-induced sideroblastic anemia
- Cyclosporine-induced hypertension
- Dapsone
- Decreased mean cell haemoglobin
- Decreased mean cell volume
- Demeton-s-methyl
- Deponit
- Di guglielmo
- Diabetic hypoglycemia
- Diamond-blackfan syndrome
- Diazinon
- Dichlorvos
- Dicrotophos
- Diencephalic syndrome
- Dimetane
- Dimorphic anemia
- Dioxathion
- Disseminated intravascular coagulation
- Disulfoton
- Double outlet right ventricle
- Down syndrome
- Doxepine-induced immune hemolytic anemia
- D-plus hemolytic uremic syndrome
- Drug allergies
- Drug-induced hypertension
- Drug-induced immune hemolytic anemia
- Drug-induced sideroblastic anemia
- Dumping syndrome
- Dyskeratosis congenita
- Earthball poisoning
- Ecstasy
- Ectopic pregnancy
- Edema
- Ehlers danlos syndrome
- Epiglotitis
- Erythroblastopenia
- Erythrocyte enzyme defects
- Erythropoietin-induced hypertension
- Estren-dameshek syndrome
- Ethanol-induced sideroblastic anemia
- Ethion
- Evan's syndrome
- Fainting
- Familial hypopituitarism
- Familial hypothyroidism
- Familial myelofibrosis
- Familial selective vitamin b12 malabsorption
- Familial wilms' tumor
- Fanconi syndrome
- Fanconi's anemia
- Favism
- Fear
- Felty syndrome
- Fensulfothion
- Fenthion
- Flotch syndrome
- Flumadine
- Folate-deficiency anemia
- Folic acid deficiency anemia
- Foradil aerolizer
- Formoterol
- Friedel heid grosshans syndrome
- Frostbite
- Functioning pancreatic endocrine tumor
- Fungizone intravenous
- Gastrointestinal bleeding
- Glaze
- Glucagonoma syndrome
- Glucose-6-phosphate dehydrogenase deficiency
- Golden chain tree poisoning
- Goodpasture's syndrome
- Gorlin-bushkell-jensen syndrome
- Graeck-imerslund disease
- Grand mal epilepsy
- Grasbeck-imerslund disease
- Grass spider poisoning
- Grief
- Hashimoto's thyroiditis
- Heart attack
- Heat exhaustion
- Heat stroke
- Hemangioma thrombocytopenia syndrome
- Hemolytic anemia
- Hemolytic-uremic syndrome
- Hemophagocytic lymphohistiocytosis
- Hemophagocytic reticulosis
- Hemorrhage
- Hereditary spherocytosis
- Hip cancer
- Hodgkin's disease
- Hookworm
- Hyperadrenalism
- Hyperaldosteronism-induced hypertension
- Hyperchromic anemia
- Hypertension
- Hypoglycemia
- Hypopituitarism
- Hypotension
- Hypothermia
- Hypothyroidism
- Hypovolemia
- Idiopathic pulmonary hemosiderosis
- Illness
- Imerslund-najman-grasbeck syndrome
- Incontinentia pigmenti
- Infective endocarditis
- Inherited hemolytic-uremic syndrome
- Inherited spherocytic anemia
- Intestinal bleeding
- Iron deficiency anemia
- Iron poisoning
- Isoniazid-induced sideroblastic anemia
- Jervell and lange-nielsen syndrome
- Juvenile megaloblastic anemia
- Juvenile rheumatoid arthritis
- Kasabach merritt syndrome
- Kentucky coffee tea poisoning
- Kotzot-richter syndrome
- Lack of sun exposure
- Lead-containing paint
- Lederer's anemia
- Leprosy
- Leukemia
- Leukonychia totalis
- Lichen sclerosis
- Licorice-induced hypertension
- Liver tumors
- Loeys-dietz syndrome
- Lymphoblastic lymphoma
- Lymphomatous thyroiditis
- Macrocytic hyperchromic anemia
- Malabsorption
- Malaria
- Malathion
- Mallory-weiss syndrome
- Marchiafava-micheli disease
- Marine turtle poisoning
- Mazindol
- Megaloblastic anemia
- Megalocytic-normochromic anemia
- Mende syndrome
- Menorrhagia
- Methidathion
- Methiocarb
- Methomyl
- Methyldopa-induced immune hemolytic anemia
- Microcytic anemia
- Microcytic hyperchromic anemia
- Microcytic hypochromic anemia
- Minitran
- Mixed connective tissue disease
- Monoamine oxidase inhibitors
- Motion sickness
- Multiple endocrine neoplasia
- Multiple myeloma
- Mycetoma
- Myelodysplastic disease
- Myelofibrosis
- Myelogenous leukemia
- Myeloproliferative disease
- Myelpathic anemia
- Myxoedema
- Neuroblastoma
- Neurofibromatosis
- Nitrates
- Nitrek
- Nitro tab
- Nitro-bid
- Nitrocine
- Nitro-derm
- Nitrodisc
- Nitro-dur
- Nitrogard
- Nitroglycerin
- Nitroglyn
- Nitrol
- Nitrolingual
- Nitrong
- Nitroquick
- Nitrostat
- Nitro-time
- Non-hereditary spherocytic anemia
- Non-hodgkin's lymphoma
- Normal genetic variation
- Normochromic anemia
- Normocytic anemia
- Nutritional anemia
- Obesity
- Oculocutaneous albinism
- Oral thrush
- Orotic aciduria hereditary
- Oroticaciduria
- Orotidylic decarboxylase deficiency
- Orthostatic hypotension
- Orthostatic intolerance
- Osteogenesis imperfecta
- Pachyonychia congenita recessive
- Pancreatic carcinoma
- Pancytopenia
- Panhypopituitarism
- Parathion
- Patent ductus arteriosus
- Pearson's anemia
- Penicillin-induced immune hemolytic anemia
- Peripheral vascular disease
- Pernicious anemia
- Persistent patency of the arterial duct
- Phenylketonuria
- Pheochromocytoma
- Phosdrin
- Physical exertion
- Plasmacytoma anaplastic
- Platelet function disorders
- Plummer-vinson syndrome
- Poems syndrome
- Poikilocytic anemia
- Post streptococcal glomerulonephritis
- Posthemorrhagic anemia
- Pramipexole
- Primary autoimmune hemolytic anemia
- Profenofos
- Prolintane
- Pseudoxanthoma elasticum
- Pulmonary edema
- Pure red cell aplasia
- Pyruvate kinase deficiency
- Quinidine-induced immune hemolytic anemia
- Raynaud's disease
- Reflex sympathetic dystrophy syndrome
- Refractory celiac disease
- Reiters syndrome
- Renal hypertension
- Renovascular hypertension
- Resistant hypertension
- Reticuloendotheliosis
- Retinopathy
- Rheumatic fever
- Rib tumor
- Riedel syndrome
- Rimantidine
- Rosai-dorfman disease
- Sandifer syndrome
- Sanorex
- Sarrouy disease
- Scurvy
- Sea sickness
- Secondary autoimmune hemolytic anemia
- Secondary hypertension
- Selective vitamin b12 malabsorption with proteinuria
- Severe asthma
- Severe gastroenteritis
- Shaken baby syndrome
- Sheehan syndrome
- Shock
- Sickle cell anemia
- Sideroblastic anemia
- Sideropenic anemia
- Sleep deprivation
- Small intestine cancer
- Sneddon syndrome
- Solitary extramedullary plasmacytoma
- Spherocytic anemia
- Spherocytosis
- Spinal shock
- Spleen cancer
- Spur-cell anemia
- Stomach upset
- Stress
- Suffocation
- Sulfasalazine
- Sulphonamide
- Survanta
- Temporal arteritis
- Temporal lobe epilepsy
- Terbufos
- Tetraethyl pyrophosphate
- Thalassemia
- Thrombocytopenia
- Thrombotic thrombocytopenic purpura
- Thrush
- Thyroid agenesis
- Thyroid hormone plasma membrane transport defect
- Thyroid agenesis
- Tornalate
- Toxin-induced sideroblastic anemia
- Transderm-nitro
- Transient bullous dermolysis of the newborn
- Transient erythroblastopenia
- Traumatic spreading depression syndrome
- Trichorhinophalangeal syndrome type i
- Triploid syndrome
- Tropical sprue
- Tuberculosis
- Turner syndrome
- Type 1 diabetes
- Uremia
- Vertigo
- Vestibulocochlear dysfunction
- Vitaligo
- Vitamin b12 deficiency
- Vitiligo
- Volume depletion
- Waardenburg syndrome
- Waldenstrom macroglobulinemia
- Warm autoimmune hemolytic anemia
- Waterhouse-friederichsen syndrome
- Weinstein kliman scully syndrome
- William's syndrome
- Wilms tumor
- Wiskott-aldrich syndrome
- Wolf-parkinson-white syndrome
- Wt limb blood syndrome
- Xerocytosis
- X-linked alpha thalassemia mental retardation syndrome
- X-linked sideroblastic anemia