Glycoside
In chemistry, glycosides are certain molecules in which a sugar part is bound to some other part. Glycosides play numerous important roles in living organisms. Many plants store important chemicals in the form of inactive glycosides; if these chemicals are needed, the glycosides are brought in contact with water and an enzyme, and the sugar part is broken off, making the chemical available for use. Many such plant glycosides are used as medications. In animals (including humans), poisons are often bound to sugar molecules in order to remove them from the body.
Formally, a glycoside is any molecule in which a sugar group is bonded through its anomeric carbon to another group via an O-glycosidic bond or an S-glycosidic bond; glycosides involving the latter are also called thioglycosides. The given definition is the one used by IUPAC. Many authors require in addition that the sugar be bonded to a non-sugar for the molecule to qualify as a glycoside, thus excluding the polysaccharides. The sugar group is then known as the glycone and the non-sugar group as the aglycone or genin part of the glycoside. 
The glycone can consist of a single sugar group (monosaccharide) or several sugar groups (oligosaccharide).

# Related compounds
Molecules containing an N-glycosidic bond are known as glycosylamines and are not discussed in this article. (Many authors in biochemistry call these compounds N-glycosides and group them with the glycosides; this is considered a misnomer and discouraged by IUPAC.)

# Chemistry
Much of the chemistry of glycosides is explained in the article on glycosidic bonds. For example, the glycone and aglycone portions can be chemically separated by hydrolysis in the presence of acid. There are also numerous enzymes that can form and break glycosidic bonds. The most important cleavage enzymes are the glycoside hydrolases, and the most important synthetic enzymes in nature are glycosyltransferases. Mutant enzymes termed glycosynthases have been developed that can form glycosidic bonds in excellent yield.
There are a great many ways to chemically synthesize glycosidic bonds. Fischer glycosidation refers to the synthesis of glycosides by the reaction of unprotected monosaccharides with alcohols (usually as solvent) in the presence of a strong acid catalyst. The Koenigs-Knorr reaction is the condensation of glycosyl halides and alcohols in the presence of metal salts such as silver carbonate or mercuric oxide.

# Classification
We can classify glycosides by the glycone, by the type of glycosidic bond, and by the aglycone.

## By glycone
If the glycone group of a glycoside is glucose, then the molecule is a glucoside; if it is fructose, then the molecule is a fructoside; if it is glucuronic acid, then the molecule is a glucuronide; etc. In the body, toxic substances are often bonded to glucuronic acid to increase their water solubility; the resulting glucuronides are then excreted.

## By type of glycosidic bond
Depending on whether the glycosidic bond lies "above" or "below" the plane of the cyclic sugar molecule, glycosides are classified as -glycosides or -glycosides. Some enzymes such as -amylase can only hydrolize -linkages; others, such as emulsin, can only affect -linkages.

## By aglycone
Glycosides are also classified according to the chemical nature of the aglycone. For purposes of biochemistry and pharmacology, this is the most useful classification.

### Alcoholic glycosides
An example of an alcoholic glycoside is salicin which is found in the genus salix. Salicin is converted in the body into salicylic acid, which is closely related to aspirin and has analgesic, antipyretic and antiinflammatory effects.

### Anthraquinone glycosides
These glycosides contain an aglycone group that is a derivative of anthraquinone. They are present in senna, rhubarb and aloes; they have a laxative effect.

### Coumarin glycosides
Here the aglycone is coumarin. An example is apterin which is reported to dilate the coronary arteries as well as block calcium channels.those obtained from dried leaves of Psoralia corylifolia have Main glycosides psoralin and corylifolin.

### Cyanogenic glycosides
In this case, the aglycone contains a cyanide group, and the glycoside can release the poisonous hydrogen cyanide if acted upon by some enzyme.  An example of these is amygdalin from almonds. Cyanogenic glycosides can be found in the fruits (and wilting leaves) of the rose family (including cherries, apples, plums, almonds, peaches, apricots, raspberries, and crabapples). Cassava, an important food plant in Africa and South America, contains cyanogenic glucosides and therefore has to be washed and ground under running water prior to consumption.

### Flavonoid glycosides
Here the aglycone is a flavonoid. This is a large group of flavonoid glycosides. Examples include:
- Hesperidin (aglycone: Hesperetin, glycone: Rutinose)
- Naringin (aglycone: Naringenin, glycone: Rutinose)
- Rutin (aglycone: Quercetin, glycone: Rutinose)
- Quercitrin (aglycone: Quercetin, glycone: Rhamnose)
Among the important effects of flavonoids are their antioxidant effect. They are also known to decrease capillary fragility.

### Phenolic glycosides (simple)
Here the aglycone is a simple phenolic structure. An example is arbutin found in the Common Bearberry Arctostaphylos uva-ursi. It has a urinary antiseptic effect.
Rutin found in rooibos tea.

### Saponins
These compounds give a permanent froth when shaken with water. They also cause hemolysis of red blood cells. Saponin glycosides are found in liquorice. Their medicinal value is due to their expectorant effect.

### Steroidal glycosides or cardiac glycosides
Here the aglycone part is a steroidal nucleus. These glycosides are found in the plant genera Digitalis, Scilla, and Strophanthus. They are used in the treatment of heart diseases e.g. congestive heart failure (historically as now recognised does not improve survivability; other agents are now preferred] and arrhythmia.

### Steviol glycosides
These sweet glycosides found in the stevia plant Stevia rebaudiana bertoni have 40-300 times the sweetness of sucrose. The two primary glycosides, stevioside and rebaudioside A, are used as natural sweeteners in many countries. These glycosides have steviol as the aglycone part. Glucose or rhamnose-glucose combinations are bound to the ends of the aglycone to form the different compounds.

### Thioglycosides
As the name implies, these compounds contain sulfur. Examples include sinigrin, found in black mustard, and sinalbin, found in white mustard.