Amoebozoa

# Overview
The Amoebozoa are a major group of amoeboid protozoa, including the majority that move by means of 
internal cytoplasmic flow.  Their pseudopodia are characteristically blunt and finger-like, 
called lobopodia.  Most are unicellular, and are common in soils and aquatic habitats, with some found as symbiotes 
-f other organisms, including several pathogens.  The Amoebozoa also include the slime moulds, multinucleate or 
multicellular forms that produce spores and are usually visible to the unaided eye.
Amoebozoa vary greatly in size.  Many are only 10-20 m in size, but they also include many of the larger 
protozoa.  The famous species Amoeba proteus may reach 800 m in length, and partly on account of 
its size is often studied as a representative cell.  Multinucleate amoebae like Chaos and 
Pelomyxa may be several millimetres in length, and some slime moulds cover several square feet.

# Morphology
The cell is typically divided into a granular central mass, called endoplasm, and a clear outer layer, called ectoplasm.  During locomotion the endoplasm flows forwards and the ectoplasm runs backwards along the outside of the cell.  Many amoeba move with a definite anterior and posterior; in essence the cell functions as a single pseudopod.  They usually produce numerous clear projections called subpseudopodia (or determinate pseudopodia), which have a defined length and are not directly involved in locomotion.
Other amoebozoans may form multiple indeterminate pseudopodia, which are more or less tubular and are mostly filled with granular endoplasm.  The cell mass flows into a leading pseudopod, and the others ultimately retract unless it changes direction.  Subpseudopodia are usually absent.  In addition to a few naked forms like Amoeba and Chaos, this includes most amoebae that produce shells.  These may be composed of organic materials, as in Arcella, or of collected particles cemented together, as in Difflugia, with a single opening through which the pseudopodia emerge.
The primary mode of nutrition is by phagocytosis: the cell surrounds potential food particles, sealing them into vacuoles where the may be digested and absorbed.  Some amoebae have a posterior bulb called a uroid, which may serve to accumulate waste, periodically detaching from the rest of the cell.  When food is scarce, most species can form cysts, which may be carried aerially and introduce them to new environments.  In slime moulds, these structures are called spores, and form on stalked structures called fruiting bodies or sporangia.
Most Amoebozoa lack flagella and more generally do not form microtubule-supported structures except during mitosis.  However, flagella occur among some archamoebae, and many slime moulds produce biflagellate gametes.  The flagella is generally anchored by a cone of microtubules, suggesting a close relationship to the opisthokonts.  The mitochondria characteristically have branching tubular cristae, but have been lost among archamoebae.

# Classification
Traditionally all amoebae with lobose pseudopods were treated together as the Lobosea, placed with other amoeboids in the phylum Sarcodina or Rhizopoda, but these were considered to be unnatural groups.  Structural and genetic studies identified the percolozoans and several archamoebae as independent groups.  In phylogenies based on rRNA their representatives were separate from other amoebae, and appeared to diverge near the base of eukaryotic evolution, as did most slime molds.
However, revised trees by Cavalier-Smith and Chao in 1996 suggested that the remaining lobosans do form a monophyletic group, and that the archamoebae and Mycetozoa are closely related to it, although the percolozoans are not.  Subsequently they emended the older phylum Amoebozoa to refer to this supergroup.  Studies based on other genes have provided strong support for the unity of this group.  Patterson treated most with the testate filose amoebae as the ramicristates, based on mitochondrial similarities, but the latter are now removed to the Cercozoa.
Amoebae are difficult to classify, and relationships within the phylum remain confused.  Originally the archamoebae and Mycetozoa were placed in a subphylum Conosa, which receives some support from molecular phylogenies, and the others were placed in a subphylum Lobosa, which is paraphyletic.  Two major classes of Lobosa have been identified, the Tubulinea and Flabellinea, but various others remain of uncertain placement. Strong similarities between Amoebozoa and Opisthokonts lead to the proposal that they form a clade called Unikonts.