TGF beta 2
Transforming growth factor-beta 2 (TGF-2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during embryonic development (alternative names: Glioblastoma-derived T-cell suppressor factor, G-TSF, BSC-1 cell growth inhibitor, Polyergin, Cetermin). It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. There are two named isoforms of this protein, created by alternative splicing of the same gene.

# Further reading
- Clark DA, Coker R (1998). "Transforming growth factor-beta (TGF-beta)". Int. J. Biochem. Cell Biol. 30 (3): 2938. doi:10.1016/S1357-2725(97)00128-3. PMID 9611771..mw-parser-output cite.citation{font-style:inherit}.mw-parser-output q{quotes:"\"""\"""'""'"}.mw-parser-output code.cs1-code{color:inherit;background:inherit;border:inherit;padding:inherit}.mw-parser-output .cs1-lock-free a{background:url("")no-repeat;background-position:right .1em center}.mw-parser-output .cs1-lock-limited a,.mw-parser-output .cs1-lock-registration a{background:url("")no-repeat;background-position:right .1em center}.mw-parser-output .cs1-lock-subscription a{background:url("")no-repeat;background-position:right .1em center}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration{color:#555}.mw-parser-output .cs1-subscription span,.mw-parser-output .cs1-registration span{border-bottom:1px dotted;cursor:help}.mw-parser-output .cs1-hidden-error{display:none;font-size:100%}.mw-parser-output .cs1-visible-error{display:none;font-size:100%}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration,.mw-parser-output .cs1-format{font-size:95%}.mw-parser-output .cs1-kern-left,.mw-parser-output .cs1-kern-wl-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right,.mw-parser-output .cs1-kern-wl-right{padding-right:0.2em}
- Wick W, Platten M, Weller M (2002). "Glioma cell invasion: regulation of metalloproteinase activity by TGF-beta". J. Neurooncol. 53 (2): 17785. doi:10.1023/A:1012209518843. PMID 11716069.
- Bissell DM (2002). "Chronic liver injury, TGF-beta, and cancer". Experimental & Molecular Medicine. 33 (4): 17990. doi:10.1038/emm.2001.31. PMID 11795478.
- Kalluri R, Neilson EG (2004). "Epithelial-mesenchymal transition and its implications for fibrosis". J. Clin. Invest. 112 (12): 177684. doi:10.1172/JCI20530. PMC 297008. PMID 14679171.
- Daopin S, Piez KA, Ogawa Y, Davies DR (1992). "Crystal structure of transforming growth factor-beta 2: an unusual fold for the superfamily". Science. 257 (5068): 36973. doi:10.1126/science.1631557. PMID 1631557.
- Schlunegger MP, Grutter MG (1992). "An unusual feature revealed by the crystal structure at 2.2 A resolution of human transforming growth factor-beta 2". Nature. 358 (6385): 4304. doi:10.1038/358430a0. PMID 1641027.
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- Bodmer S, Podlisny MB, Selkoe DJ,  et al. (1990). "Transforming growth factor-beta bound to soluble derivatives of the beta amyloid precursor protein of Alzheimer's disease". Biochem. Biophys. Res. Commun. 171 (2): 8907. doi:10.1016/0006-291X(90)91229-L. PMID 2119582.
- Webb NR, Madisen L, Rose TM, Purchio AF (1989). "Structural and sequence analysis of TGF-beta 2 cDNA clones predicts two different precursor proteins produced by alternative mRNA splicing". DNA. 7 (7): 4937. doi:10.1089/dna.1.1988.7.493. PMID 2850146.
- Madisen L, Webb NR, Rose TM,  et al. (1988). "Transforming growth factor-beta 2: cDNA cloning and sequence analysis". DNA. 7 (1): 18. doi:10.1089/dna.1988.7.1. PMID 3162414.
- Barton DE, Foellmer BE, Du J,  et al. (1989). "Chromosomal mapping of genes for transforming growth factors beta 2 and beta 3 in man and mouse: dispersion of TGF-beta gene family". Oncogene Res. 3 (4): 32331. PMID 3226728.
- de Martin R, Haendler B, Hofer-Warbinek R,  et al. (1988). "Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-beta gene family". EMBO J. 6 (12): 36737. PMC 553836. PMID 3322813.
- Marquardt H, Lioubin MN, Ikeda T (1987). "Complete amino acid sequence of human transforming growth factor type beta 2". J. Biol. Chem. 262 (25): 1212731. PMID 3476488.
- Philip A, Bostedt L, Stigbrand T, O'Connor-McCourt MD (1994). "Binding of transforming growth factor-beta (TGF-beta) to pregnancy zone protein (PZP). Comparison to the TGF-beta-alpha 2-macroglobulin interaction". Eur. J. Biochem. 221 (2): 68793. doi:10.1111/j.1432-1033.1994.tb18781.x. PMID 7513640.
- Lin HY, Moustakas A, Knaus P,  et al. (1995). "The soluble exoplasmic domain of the type II transforming growth factor (TGF)-beta receptor. A heterogeneously glycosylated protein with high affinity and selectivity for TGF-beta ligands". J. Biol. Chem. 270 (6): 274754. doi:10.1074/jbc.270.6.2747. PMID 7852346.
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- Fromigue O, Marie PJ, Lomri A (1998). "Bone morphogenetic protein-2 and transforming growth factor-beta2 interact to modulate human bone marrow stromal cell proliferation and differentiation". J. Cell. Biochem. 68 (4): 41126. doi:10.1002/(SICI)1097-4644(19980315)68:43.0.CO;2-T. PMID 9493905.
- Mori T, Kawara S, Shinozaki M,  et al. (1999). "Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: A mouse fibrosis model". J. Cell. Physiol. 181 (1): 1539. doi:10.1002/(SICI)1097-4652(199910)181:13.0.CO;2-K. PMID 10457363.