HIV/AIDS in Yunnan
Chinas first AIDS case was identified in 1985 in a dying tourist. In 1989, the first indigenous cases were reported as an outbreak in 146 infected heroin users in Yunnan province, near Chinas southwest border.

# The heroin flow
Heroin flows into Yunnan Province from neighboring Vietnam, Laos and Myanmar, bringing with it HIV. The province's first cases were reported in 1989. With a population of 44 million, Yunnan now has only 200 health workers trained for the disease. Officials estimate that the province has 80,000 infected people, most of them intravenous drug users who have spread the disease by sharing needles. In Gejiu, a city of 310,000 people on a route favored by drug traffickers, initial rounds of AIDS testing in recent years found more than 1,000 people with HIV, nearly all drug users or prostitutes. Unlike some other provinces, Yunnan has welcomed international nonprofit groups and support from Britain, Australia and, more recently, the United States.

# '3 Needles'
3 Needles is a 2005 dramatic film depicted the Yunnan's live during the survival of HIV/AIDS epidemic. One of protagonist, a pregnant black-market-operative Lucy Liu, makes her living as a blood-smuggler. When several blood-donors begin to get sick and die, she realize the jeopardy for entire village's safety and beyond. 3 Needles is an attempt to visualize the profound experience of Gao Yaojie and many others as we can read in The New York Times sequel.

# Needle exchange
Since 2001, the of the State Council of the People's Republic of China has officially advocated needle social marketing as an HIV prevention measure. Evidence from research and study tours to countries such as Australia, which runs successful needle exchange programmes, prompted the Ministry of Health (China) to support the first such programme in Yunnan province and Guangxi Zhuang Autonomous Region in 1999. On the basis of the successes of the pilot, the programme began scale-up in 2004 and plans are in place to open an additional 1500 methadone maintenance treatment clinics for about 300 000 heroin users by 2008. A National Training Centre for methadone maintenance treatment has been established in Yunnan to provide clinical and technical support.

# Commercial sex
Commercial sex work is illegal in China; hence, brothels are illegal and commercial sex workers operate out of places of entertainment (eg, karaoke bars), hotels, hair-dressing salons, or on the street. The traditional strategy for controlling HIV transmission through commercial sex workers has been the development of stricter laws to prevent risky behaviours, accompanied by raids on suspected sex establishments by public security officials. In 199697, following the success of prevention interventions in neighbouring Thailand, the Chinese CDC launched the first intervention projects to promote safer sex behaviours to prevent HIV and other sexually transmitted diseases in commercial sex workers working at entertainment establishments in Yunnan.

# The numbers
In 2002, a United Nations-commissioned report, entitled Chinas Titanic peril, estimating that China had about 1 million cases of HIV, and that it was on the brink of an explosive HIV/AIDS epidemic...with an imminent risk to widespread dissemination to the general population. The report continued: a potential HIV/AIDS disaster of unimaginable proportion now lies in wait. A few months later, the US National Intelligence Council estimated that 1-2 million people were living with HIV in China, and predicted 1015 million cases by 2010. Other reports at this time were similarly pessimistic: from the Center for Strategic and International Studies (Washington, DC, USA), HIV/AIDS was referred to as Chinas timebomb; and from the American Enterprise Institute as the AIDS typhoon. However, as Wu and colleagues note, by 2006 the number of people living with HIV/AIDS is estimated to be 650 000a figure revised downwards by 200 000 from 2005. After a slow start and reluctance to recognise the existence of risk activities in its population and of the HIV epidemic, China has responded to international influences, media coverage, and scientific evidence to take bold steps to control the epidemic, using scientifically validated strategies. A Joint Assessment of HIV/AIDS Prevention, Treatment and Care in China (2004), developed jointly by UNAIDS and the State Council of China, estimated that China had 840 000 people living with HIV/AIDS. This figure has been revised down to 650 000 in 2005 in light of more representative data collection and more appropriate estimation methods.

# Yunnan ahead
Yunnan province has shown strong support for implementation and advocacy of harm-reduction strategies that reduce HIV transmission in its many drug users, whereas Henan province had been slower to respond to the needs of former plasma donors in the early stages of the epidemic. The distribution of HIV in China is not even, and is concentrated in areas with high drug use (eg, Yunnan, Guangxi, Xinjiang, and Sichuan) and in areas where people were infected through unsafe blood or plasma donation (eg, Henan, Anhui, Hebei, Shanxi, and Hubei). The number of cases ranges dramatically between provinces (see the map of China on your right), with, for example, just 20 cases reported from Tibet but well over 40 000 in neighbouring Yunnan.