Persius/hicric huggingface dataset:
Sandbox/NCT

# Overview
Narrow complex tachycardia (NCT) is characterized by heart rate > 100 beats per minute and QRS complex of duration < 120 milliseconds.  The NCT may originate in the sinus node, the atria, the AV node, the His bundle, or combination of these tissues causing rapid activation of the ventricles.  Diagnosis of NCT is established by surface ECG in correlation with history and physical examination.  Hemodynamically unstable patients should receive urgent cardioversion.

# Causes

## Life Threatening Causes
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.
- Wolff-Parkinson-White syndrome
- VT

## Common Causes
- Atrial fibrillation
- Atrial flutter
- Atrial tachycardia
- AVNRT
- AVRT

# Diagnosis
Shown below is an algorithm summarizing the approach for diagnosing narrow complex tachycardia according to the 2003 ACC/AHA/ESC guidelines for the management of patients with supraventricular arrhythmias.
 ECG: electrocardiogram; SVT: supraventricular tachycardia; ms: Milliseconds; bpm: beats per minute; NCT: Narrow complex tachycardia; AV:  atrioventricular; AVNRT: atrioventricular nodal reciprocating tachycardia; MAT: multifocal atrial tachycardia; ms: milliseconds; PJRT: permanent form of junctional reciprocating tachycardia

# Treatment

## Initial Approach

## Short Term Treatment of SVT in a Hemodynamically Stable Patient
Shown below is an algorithm summarizing the management of narrow complex tachycardia according to the 2003 ACC/AHA/ESC guidelines for the management of patients with supraventricular arrhythmias. 
AF:  atrial fibrillation; AV: atrioventricular; AVNRT: atrioventricular nodal reciprocating tachycardia; AVRT: atrioventricular reciprocating tachycardia; BBB: bundle-branch block; ECG: electrocardiography;  IV: intravenous; LV: left ventricle; SVT: supraventricular tachycardia; VT: ventricular tachycardia
 Adenosine should be used cautiously in patients with severe coronary artery disease and may produce AF.
 Ibutilide is especially indicated for patients with atrial flutter but should not be used in patients with ejection fraction less than 30% as it increases risk of polymorphic VT.
 EKG strips are a courtesy from ECGpedia.

## Treatment of Specific Supraventricular Arrhythmias
Sandbox/v22

# The WikInfect Project  Mission Statement
 Thank you for your interest in the WikInfect Project!
 The WikInfect Project covers informations of anti-infective agents from FDA package insert as well as treatment recommendations for organ- and pathogen-based infections developed on the basis of guidelines, consensus statements, review articles, and expert opinions by the Infection Mission Force (IMF) team.
 The content provided herein is not intended to supplant but supplement clinical judgment. Given the variable nature of epidemiologic scenarios, mandatory adjustments in treatment and infectious disease consultations should always be considered to optimize patient care.
 Please let us know if there is specific or more detailed information you would like to see included. Team IMF welcomes your comments to email.
Sandbox/v24

# Current WikiDoc User Pages
- Once you create a username, you have a User Page.
- On this page you can tell everyone about yourself and your medical qualifications.
- We recommend that post a brief biography including your medical training, degree, specialty, research, or anything else you would like our users to know about you. Do not post your DEA number, medical license number or any other sensitive information
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# WikiDoc Physician Space Page
- Simply click here to see an example of a WikiDoc.
- You can click on your user name at the very top of the page and edit it as desired.

# Discussion Page
- Every registered user has a discussion  page (also known as a talk page). To view it, click on the red discussion  tab at the top of the page.
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- Occasionally, check your own discussion page (by clicking on the my talk link next to your user name at the top of the screen). This is where other members of the community may sometimes leave messages for you.
Sandbox/v25

# How to Get Started
- If you would like to watch a video on how to get started click the Getting Started Video
- Experiment with editing in the Sandbox

# Visit the Help Page
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# Write a new article...
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Sandbox/v30

# Thymic Tumor, Resectable Adapted from NCCN Guidelines: Thymomas and Thymic Carcinomas
 CT scan every 6 months for 2 years, then annually every 5 years for thymic carcinoma and every 10 years for thymoma.

### Chemotherapy Regimens
Return to top

### Radiation Dose
Return to top
- A dose of 60-70 Gy should be given to patients with unresectable disease.
- For adjuvant treatment, the radiation dose consists of 45-50 Gy for clear/close margins and 54 Gy for microscopically positive resection margins. A total dose of 60 Gy and above should be given to patients with gross residual disease (similar to patients with unresectable disease), when conventional fractionation (1.8 to 2.0 Gy per daily fraction) is applied.
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Sandbox:MAD

# Overview
If left untreated, patients with lymphatic filariasis may progress to develop chronic lymphedema, hydrocele, skin pigmentation, and chyluria. Prognosis is generally good in early cases, but in chronic cases the disease can leave an individual severely disabled with genital damage.

# Natural history
Lymphatic filariasis can be asymptomatic or symptomatic. Symptoms may include acute adenolymphangitis, filarial fever, and tropical pulmonary eosinophilia. If left untreated, disease can progress to lymphatic dilatation, abnormalities in lymphatic drainage, and microscopic hematuria and proteinuria.

# Complications
Complications that may develop as a result of lymphatic filariasis include:
- Lymphedema: It refers to non-pitting edema in limbs due to chronic inflammation and obstruction of lymphatic vessels. Lymphedema commonly occurs in upper limbs and may involve breasts. Lower limb is a common place for lymphedema that commonly spares genitalia except W.bancrofti endemic areas.
- Hydrocele: it was also reported up to 30 cm in diameter due to lymphedema in the genitalia that may lead to bacterial infection. Some cases of filariasis of the ovary and mesosalpinx were also reported.
- Renal involvement: Increased intestinal lymph drainage in renal vessels causes loss of lymph fluid in urine giving it milky appearance.

# Prognosis
Early or mild filariasis, including acute inflammatory episodes, typically responds well to treatment. It can be reduced and prevented with simple measures of hygiene, skin care, exercise, and elevation of affected limbs, chronic infection does not. Filariasis does not commonly lead to mortality, however, disease can leave an individual severely disabled with genital damage or elephantiasis. Lymphatic filariasis is the second leading cause of disability worldwide with 40 million persons suffering from complications that limit occupational activities, educational and employment opportunities, and mobility.
Sandbox:MRI

# Overview
- There are no MRI findings associated with .
OR
-  MRI may be helpful in the diagnosis of . Findings on MRI suggestive of/diagnostic of  include , , and .
OR
- There are no MRI findings associated with . However, a MRI may be helpful in the diagnosis of complications of , which include , , and .

# MRI
- There are no MRI findings associated with .
OR
-  MRI may be helpful in the diagnosis of . Findings on MRI suggestive of/diagnostic of  include:
OR
- There are no MRI findings associated with . However, a MRI may be helpful in the diagnosis of complications of , which include:
Sandbox:P.L
- Median interval of transplantation - 4 years. (range .25-30.1) Fatality rate: 17.4% (4/23).
- Renal transplant patients of all ages groups are at a higher risk of COVID-19 due to immunosuppression may develop COVID-19.
- The youngest renal transplant patient who died of COVID-19 according to analysis of 14 studies was 71 years old.
-  Wells, Samuel A.; Pacini, Furio; Robinson, Bruce G.; Santoro, Massimo (2013). "Multiple Endocrine Neoplasia Type 2 and Familial Medullary Thyroid Carcinoma: An Update". The Journal of Clinical Endocrinology & Metabolism. 98 (8): 31493164. doi:10.1210/jc.2013-1204. ISSN 0021-972X..mw-parser-output cite.citation{font-style:inherit}.mw-parser-output q{quotes:"\"""\"""'""'"}.mw-parser-output code.cs1-code{color:inherit;background:inherit;border:inherit;padding:inherit}.mw-parser-output .cs1-lock-free a{background:url("")no-repeat;background-position:right .1em center}.mw-parser-output .cs1-lock-limited a,.mw-parser-output .cs1-lock-registration a{background:url("")no-repeat;background-position:right .1em center}.mw-parser-output .cs1-lock-subscription a{background:url("")no-repeat;background-position:right .1em center}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration{color:#555}.mw-parser-output .cs1-subscription span,.mw-parser-output .cs1-registration span{border-bottom:1px dotted;cursor:help}.mw-parser-output .cs1-hidden-error{display:none;font-size:100%}.mw-parser-output .cs1-visible-error{display:none;font-size:100%}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration,.mw-parser-output .cs1-format{font-size:95%}.mw-parser-output .cs1-kern-left,.mw-parser-output .cs1-kern-wl-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right,.mw-parser-output .cs1-kern-wl-right{padding-right:0.2em}
Sandbox: DD
must be differentiated from other diseases causing oral lesions such as leukoplakia and herpes simplex virus infection.
-  Ann M. Gillenwater, Nadarajah Vigneswaran, Hanadi Fatani, Pierre Saintigny & Adel K. El-Naggar (2013). "Proliferative verrucous leukoplakia (PVL): a review of an elusive pathologic entity!". Advances in anatomic pathology. 20 (6): 416423. doi:10.1097/PAP.0b013e3182a92df1. PMID 24113312. Unknown parameter |month= ignored (help)CS1 maint: Multiple names: authors list (link) .mw-parser-output cite.citation{font-style:inherit}.mw-parser-output q{quotes:"\"""\"""'""'"}.mw-parser-output code.cs1-code{color:inherit;background:inherit;border:inherit;padding:inherit}.mw-parser-output .cs1-lock-free a{background:url("")no-repeat;background-position:right .1em center}.mw-parser-output .cs1-lock-limited a,.mw-parser-output .cs1-lock-registration a{background:url("")no-repeat;background-position:right .1em center}.mw-parser-output .cs1-lock-subscription a{background:url("")no-repeat;background-position:right .1em center}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration{color:#555}.mw-parser-output .cs1-subscription span,.mw-parser-output .cs1-registration span{border-bottom:1px dotted;cursor:help}.mw-parser-output .cs1-hidden-error{display:none;font-size:100%}.mw-parser-output .cs1-visible-error{display:none;font-size:100%}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration,.mw-parser-output .cs1-format{font-size:95%}.mw-parser-output .cs1-kern-left,.mw-parser-output .cs1-kern-wl-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right,.mw-parser-output .cs1-kern-wl-right{padding-right:0.2em}
-  Andres E, Zimmer J, Affenberger S, Federici L, Alt M, Maloisel F. (2006). "Idiosyncratic drug-induced agranulocytosis: Update of an old disorder". Eur J Intern Med. 17 (8): 52935. Text "pmid 17142169" ignored (help)CS1 maint: Multiple names: authors list (link)
-   title="By Internet Archive Book Images , via Wikimedia Commons" href=":A_manual_of_syphilis_and_the_venereal_diseases%2C_(1900)_(14595882378).jpg"
-  Feikin DR, Lezotte DC, Hamman RF, Salmon DA, Chen RT, Hoffman RE (2000). "Individual and community risks of measles and pertussis associated with personal exemptions to immunization". JAMA. 284 (24): 314550. PMID 11135778.CS1 maint: Multiple names: authors list (link)
-  Ratnam S, West R, Gadag V, Williams B, Oates E (1996). "Immunity against measles in school-aged children: implications for measles revaccination strategies". Can J Public Health. 87 (6): 40710. PMID 9009400.CS1 maint: Multiple names: authors list (link)
Sandbox: PE

# Overview
Examination reveals signs of acute abdomen and in advanced cases, shows signs of shock and septicemia.

# Physical Examination

## Appearance of the patient
- Patients with peritonitis are usually ill-appearing.
- Initially they appear alerted, restless and irritable.
- They may later become apathetic and delirious.
- They are often noticed lying quietly supine, on the bed with the knees flexed and with frequent limited intercostal respirations because any motion intensifies the abdominal pain.

## Vital Signs

### Temperature
- Hyperthermia (temperatures as high as 42 C) is a sign of infection and hypothermia (temperatures as low as 35 C) indicates septic shock.
- Hypothermia is a grave sign,seen late in the course of the disease in patients with on-going intra-abdominal sepsis or septic shock.

### Blood Pressure
- Hypertension can be seen if associated with any heart condition or renal disease.
- The blood pressure is maintained within normal limits early in the disease process but as peritonitis progresses, the blood pressure decreases due to volume loss diarrhea or severe ascites.

### Pulse
- Tachycardia with weak, thready peripheral pulses represents decreased effective circulating blood volume, indicating a stage of shock later in the disease.
- May be normal or increased in rate due to infection.
- It may be low in volume due to dehydration.

### Respiration
- Tachypnea due to infection and increased demand.

## Skin
- Skin over abdomen is tense due to ascites.
- Skin changes such as spider nevus, palmar erythema, large abdominal wall collateral veins are suggestive of parenchymal liver disease and portal hypertension

## Eyes
- Jaundice may be seen in cases of liver cirrhosis.
- Periorbital puffiness may be noticed in cases of renal failure.

## Neck
- Jugular venous distension may be seen in cases of heart failure causing ascites.

## Heart
- Signs of heart failure may be seen like S3.

## Lungs
- Signs of any infection, or signs of volume overload in lungs due to heart failure.

## Neurologic
Following may be noticed when spontaneous bacterial peritonitis complicates or due to underlying liver or renal failure.
- Stupor
- Confusion
- Seizures

## Abdomen
- Usually tense and distended due to ascites
- Marked abdominal tenderness to palpation is present.
- Shifting dullness on percussion is noted in patients with ascites, but may be painful due to infection.
- Bowel sounds vary along the course of peritonitis, are initially hypoactive, and may disappear later.
- Absence of bowel sounds may be the only manifestation of peritonitis in some patients, and a high index of suspicion is necessary
- The absence of any of these findings does not exclude peritonitis.

## Extremities
- When present, peripheral edema in patients with liver disease is usually found in the lower extremities and occasionally may involve the abdominal wall. Patients with nephrotic syndrome or cardiac failure may have total body edema (anasarca).
Sandbox MEN

# Overview

# Classification

# Pathophysiology
- The term multiple endocrine neoplasia (MEN) encompasses several distinct syndromes featuring tumors of endocrine glands, each with its own characteristic pattern.  In some cases, the tumors are malignant, in others, benign. Benign or malignant tumors of nonendocrine tissues occur as components of some of these tumor syndromes.
- MEN syndromes are inherited as autosomal dominant disorders.

## Comparison
Percentages in table below refer to how large fraction of people with the MEN type develop the neoplasia type.
 of patients with MEN1 and gastrinoma

## Associated Conditions
- Von Hippel-Lindau disease
- Carney complex

# Treatment

## Surgery
- Surgery is the mainstay of treatment for tumors of multiple endocrine neoplasia.
Sandbox MWH

# Famous Cases
The following are a few famous cases of narcolepsy:
- Jimmy Kimmel, American late-night talk show host, actor, producer, comedian, and writer
- Harold M. Ickes, former deputy White House chief of staff for President Bill Clinton and a leading figure in the His administration's healthcare reform initiative
- Arthur Lowe, a British actor who played iconic Captain Mainwaring in the British sitcom Dad's Army
- Nastassja Aglaia Kinski, German actress, and former model
- George M. Church, molecular geneticist, molecular engineer, and chemist, who is a Professor of Genetics and Professor of Health Sciences at Harvard
- Teresa Nielsen Hayden, American science fiction editor, fanzine writer, and essayist who has a famous weblog, named Making Light
- Franck Bouyer, French former road racing cyclist who was unable to compete or train without treatment with Modafinil
- Gabe Barham, former Drummer for American post-hardcore band Sleeping With Sirens
- Jinkx Monsoon (real name is Jerick Hoffer), Seattle Drag Queen, stage performer, comedian and singer who is the winner of the fifth season of RuPaul's Drag Race
- Aaron Flahavan, former English (Portsmouth) football Goalkeeper
- Paul Gonsalves, Jazz tenor saxophonist
Sandbox cjp

# Pregnancy
Here is some information about the use of the drug in pregnant women from the FDA.
Here is some information about the use of the drug in pregnant women from Australia.

# Labor and Delivery
Here is some information about the use of the drug in labor and delivery.

# Nursing Mothers
Here is some information about the use of the drug in women who are nursing

# Pediatric Use
Here is some information about the use of the drug in children.

# Geriatic Use
Here is some information about the use of the drug in the elderly.

# Gender
Here is some information about the use of the drug in

# Race
Here is some information about the use of the drug in people of this ethnicity.

# Renal Impairment
Here is some information about the use of the drug in people who with renal impairment.

# Hepatic Impairment
Here is some information about the use of the drug in people with hepatic impairment.

# Females of Reproductive Potential and Males
Here is some information about the use of the drug in women of reproductive potential.

# Immunocompromised Patients
Here is some information about the use of the drug in people who are immunocompromised.
Sandbox dfd
1.  BEFORE YOU START
1.1  Resources
1.1.1  DailyMed
1.1.2  Drugs@FDA
1.1.3  Pillbox
1.1.4  Drug Information Portal
1.1.5 MedlinePlus
1.2  Generic name, active ingredient, formulation, combination, trade name, label
1.2.1  What is the generic name?
1.2.2  What is the active ingredient? Is there more than one formulation for the active ingredient?
1.2.3  Is the active ingredient provided as combinations with other active ingredients?
1.2.4  What is the trade name?
1.2.5  Which label should be used?
1.2.6  Example
2.  Creating or editing a drug page
2.1  Landing page
2.1.1  Go to WikiDoc.
2.1.2  Search with the generic name.
2.1.3  The generic name page should be organized as a landing page if multiple formulations or combinations exist.
2.1.4  At the top of the landing page, place the links (as  headings) of formulations and/or combinations followed by trade names in parentheses (See Section 1.2 for instructions).
2.1.5  Redirect the trade name pages to the generic name with formulation pages.
2.1.6  Create or edit the Overview section and Category section.
2.2  Using the Drug Project Form
2.2.1  To create a drug page, Go to Form:DrugProjectForm.
2.2.2  Use the appropriate title for the drug page.
2.2.3  Enter the title for the drug page in the field and left-click on the "Create or edit a Drug Page" button.
2.2.4  Follow the instructions under each tab to insert contents.
2.2.5  Left-click on the "Save" button after completing each tab to minimize the risk of losing progress.
2.2.6  Quality check the completed section before proceeding to the next section.