Oral lesions
Synonyms and keywords: Oral cavity lesions, Oral cavity ulcers, Oral cavity infections, Mouth ulcers, Mouth lesions.

# Overview
In many cases, mouth sores are attributed to herpes simplex virus and idiopathic aphthous stomatitis. Oral lesions can be indicative of a more serious underlying condition. A full review of the systems and a full skin exam are necessary to obtain an accurate diagnosis.

# Pathophysiology

# Differential diagnosis of oral cavity lesions
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# Causes

## Causes in Alphabetical Order
- Agranulocytosis
- Aphthous stomatitis
- Allergic contact dermatitis
- Behcet's disease
- Bollus disease
- Chemotherapy drugs
- Erythema multiforme
- Herpes stomatitis
- Histoplasmosis
- Primary syphilis
- Self limited viral disease
- Squamous cell carcinoma

# Diagnosis

## History and Symptoms
- Past medical/medicinal history
- If the lesions occur in the same locations every time, culpit is HSV
- Consider the patients sexual history
- Evaluate open and mucosal lesions
- Lichen planus - lacy white plaques

## Laboratory Findings
- Culture for HSV-1
- RPR
- CBC
- Punch biopsy

# Treatment

## Medical Therapy

### Acute Pharmacotherapies
- Orabase and topical steroids can increase speed of healing
- Aphthous stomatitis - intralesional triamcinalone injections
- HSV (recurrent) - acyclovir
- Bollous disease - corticosteroids