Isocarboxazid

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# Black Box Warning

# Overview
Isocarboxazid is a MAOI that is FDA approved for the {{{indicationType}}} of depression. There is a Black Box Warning for this drug as shown here.  Common adverse reactions include constipation, nausea, xerostomia, dizziness, headache, insomnia..

# Adult Indications and Dosage

## FDA-Labeled Indications and Dosage (Adult)
- Depression
- Initial: 20 mg/day PO into 2 doses, increase every 2-4 days by 10 mg, to a maximum of 40 mg in first week. Then increase to 20 mg/week to a max of 60 mg/day.
- Maintenance: Decrease dose slowly to minimum effective dosage

## Off-Label Use and Dosage (Adult)

### Guideline-Supported Use
There is limited information about Off-Label Guideline-Supported Use of Isocarboxazid in adult patients.

### NonGuideline-Supported Use
There is limited information about Off-Label NonGuideline-Supported Use of Isocarboxazid in adult patients.

# Pediatric Indications and Dosage

## FDA-Labeled Indications and Dosage (Pediatric)
safety in under 16 years of age have not been established.

## Off-Label Use and Dosage (Pediatric)

### Guideline-Supported Use
There is limited information about Off-Label Guideline-Supported Use of Isocarboxazid in pediatric patients.

### NonGuideline-Supported Use
There is limited information about Off-Label NonGuideline-Supported Use of Isocarboxazid in pediatric patients.

# Contraindications
There is limited information regarding Isocarboxazid Contraindications in the drug label.

# Warnings
There is limited information regarding Isocarboxazid Warnings' in the drug label.

# Adverse Reactions

## Clinical Trials Experience
There is limited information regarding Isocarboxazid Clinical Trials Experience in the drug label.

## Postmarketing Experience
There is limited information regarding Isocarboxazid Postmarketing Experience in the drug label.

# Drug Interactions
There is limited information regarding Isocarboxazid Drug Interactions in the drug label.

# Use in Specific Populations

### Pregnancy
Pregnancy Category (FDA): 
There is no FDA guidance on usage of Isocarboxazid in women who are pregnant.
Pregnancy Category (AUS): 
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Isocarboxazid in women who are pregnant.

### Labor and Delivery
There is no FDA guidance on use of Isocarboxazid during labor and delivery.

### Nursing Mothers
There is no FDA guidance on the use of Isocarboxazid in women who are nursing.

### Pediatric Use
There is no FDA guidance on the use of Isocarboxazid in pediatric settings.

### Geriatic Use
There is no FDA guidance on the use of Isocarboxazid in geriatric settings.

### Gender
There is no FDA guidance on the use of Isocarboxazid with respect to specific gender populations.

### Race
There is no FDA guidance on the use of Isocarboxazid with respect to specific racial populations.

### Renal Impairment
There is no FDA guidance on the use of Isocarboxazid in patients with renal impairment.

### Hepatic Impairment
There is no FDA guidance on the use of Isocarboxazid in patients with hepatic impairment.

### Females of Reproductive Potential and Males
There is no FDA guidance on the use of Isocarboxazid in women of reproductive potentials and males.

### Immunocompromised Patients
There is no FDA guidance one the use of Isocarboxazid in patients who are immunocompromised.

# Administration and Monitoring

### Administration
There is limited information regarding Isocarboxazid Administration in the drug label.

### Monitoring
There is limited information regarding Isocarboxazid Monitoring in the drug label.

# IV Compatibility
There is limited information regarding the compatibility of Isocarboxazid and IV administrations.

# Overdosage
There is limited information regarding Isocarboxazid overdosage.  If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.

# Pharmacology

## Mechanism of Action
There is limited information regarding Isocarboxazid Mechanism of Action in the drug label.

## Structure
There is limited information regarding Isocarboxazid Structure in the drug label.

## Pharmacodynamics
There is limited information regarding Isocarboxazid Pharmacodynamics in the drug label.

## Pharmacokinetics
There is limited information regarding Isocarboxazid Pharmacokinetics in the drug label.

## Nonclinical Toxicology
There is limited information regarding Isocarboxazid Nonclinical Toxicology in the drug label.

# Clinical Studies
There is limited information regarding Isocarboxazid Clinical Studies in the drug label.

# How Supplied
There is limited information regarding Isocarboxazid How Supplied in the drug label.

## Storage
There is limited information regarding Isocarboxazid Storage in the drug label.

# Images

## Drug Images

## Package and Label Display Panel

# Patient Counseling Information
(Patient Counseling Information)

# Precautions with Alcohol
Alcohol-Isocarboxazid interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

# Brand Names
There is limited information regarding Isocarboxazid Brand Names in the drug label.

# Look-Alike Drug Names
There is limited information regarding Isocarboxazid Look-Alike Drug Names in the drug label.

# Drug Shortage Status
Drug Shortage

# Price