Persius/hicric huggingface dataset:
CPG Sec. 525.250 Cloves - Adulteration with 
Stems 
REGULATORY ACTION GUIDANCE: 
The following represents criteria for direct reference seizure *requests to the Office of Human 
and Animal Food Operations (OHAFO) in consultation with the Office of Enforcement and 
Import Operations (OEIO) and CFSAN, and for direct citation by the appropriate Field Office 
within the Human and Animal Food Program*: 
The cloves contain an average of 5% or more stems by weight. 
REMARKS: 
Since the majority of spices are imported, determine that the lot in question has not been 
previously examined and released by FDA as an import. If the lot has been examined and 
released previously, submit all available facts to CFSAN/Office of *Compliance*/Division of 
Enforcement (HFS-605) for seizure consideration in the usual manner. 
SPECIMEN CHARGE: 
Article adulterated while held for sale after shipment in interstate commerce, within meaning of 
21 U.S.C. 342(b)(2), in that clove stems have been substituted wholly or in part for cloves. 
*Material between asterisks is new or revised.* 
Issued: 10/1/80 
Revised: 3/95, 5/05 
Updated: 11/29/05
CPG Sec. 525.300 Condimental Seeds Other 
than Fennel Seeds and Sesame Seeds - 
Adulteration by Mammalian Excreta 
REGULATORY ACTION GUIDANCE: 
The following represents criteria for direct reference seizure *requests to the Office of Human 
and Animal Food Operations (OHAFO) in consultation with the Office of Enforcement and 
Import Operations (OEIO) and CFSAN, and for direct citation by the appropriate Field Office 
within the Human and Animal Food Program: 
If the condimental seeds contain an average of 3 milligrams or more of mammalian excreta per 
pound. 
REMARKS: 
Since the majority of spices are imported, determine that the lot in question has not been 
previously examined and released by FDA as an import. If the lot has been examined and 
released previously, submit all available facts to CFSAN/Office of *Compliance*/Division of 
Enforcement (HFS-605) for seizure consideration in the usual manner. 
SPECIMEN CHARGE: 
Article adulterated while held for sale after shipment in interstate commerce, within meaning of 
21 U.S.C. 342(a)(3), in that it consists wholly or in part of a filthy substance by reason of 
presence therein of excreta. 
*Material between asterisks is new or revised.* 
Issued: 10/1/80 
Revised: 3/95, 5/05 
Updated: 11/29/05
CPG Sec. 525.325 Cumin Seed - Adulteration 
with Sand and Grit 
REGULATORY ACTION GUIDANCE: 
The following represents criteria for direct reference seizure *requests to the Office of Human 
and Animal Food Operations (OHAFO) in consultation with the Office of Enforcement and 
Import Operations (OEIO) and CFSAN, and for direct citation by the appropriate Field Office 
within the Human and Animal Food Program*: 
The cumin seed contains an average of 9.5% or more ash and/or 1.5% or more acid insoluble 
ash. 
REMARKS: 
Since the majority of spices are imported, determine that the lot in question has not been 
previously examined and released by FDA as an import. If the lot has been examined and 
released previously, submit all available facts to CFSAN/Office of *Compliance*/Division of 
Enforcement (HFS-605) for seizure consideration in the usual manner. 
SPECIMEN CHARGE: 
Article adulterated while held for sale after shipment in interstate commerce, within meaning of 
21 U.S.C. as follows: 342(a)(3) in that it is unfit for food by reason or presence therein of sand 
and grit; 342(b)(2) in that sand and grit have been substituted wholly or in part for cumin seed. 
*Materials between asterisks are new or revised* 
Issued: 10/1/80 
Revised: 3/95, 5/05 
Updated: 11/29/05
CPG Sec. 525.330 Curry Powder - Adulteration 
by Insect and Rodent Filth 
REGULATORY ACTION GUIDANCE: 
The following represents the criteria for direct reference seizure *requests to the Office of 
Human and Animal Food Operations (OHAFO) in consultation with the Office of Enforcement 
and Import Operations (OEIO) and CFSAN, and for direct citation by the appropriate Field 
Office within the Human and Animal Food Program*: 
1.  Insect Filth: 
The curry powder contains an average of 100 or more insect fragments per 25 grams;  
 
Or 
 
2.  Rodent Filth: 
The curry powder contains an average of 4 or more rodent hairs per 25 grams. 
 
REMARKS: 
Since the majority of spices are imported, determine that the lot in question has not been 
previously examined and released by FDA as an import. If the lot has been examined and 
released previously, submit all available facts to CFSAN/Office of *Compliance*/Division of 
Enforcement (HFS-605) for seizure consideration in the usual manner.  
SPECIMEN CHARGE: 
Article curry powder adulterated (when introduced into and while in interstate commerce), 
within meaning of 21 U.S.C. 342(a)(3), in that it consists wholly or in part of a filthy substance 
by reason of presence therein of (insects), (insect webbing), (insect excreta), and (rodent hairs). 
*Materials between asterisks are new or revised* 
Issued: 10/1/80 
Revised: 3/95, 5/05 
Updated: 11/29/05
CPG Sec. 525.350 Fennel Seed - Adulteration by 
Mammalian Excreta; Insects 
REGULATORY ACTION GUIDANCE: 
The following represents the criteria for direct reference seizure *requests to the Office of 
Human and Animal Food Operations (OHAFO) in consultation with the Office of Enforcement 
and Import Operations (OEIO) and CFSAN, and for direct citation by the appropriate Field 
Office within the Human and Animal Food Program*: 
1.  Insects and Mammalian Excreta: 
The fennel seed in 20% or more of the subsamples contain mammalian excreta and/or insects;  
or 
2.  Mammalian Excreta: 
The fennel seed contains an average of 3 milligrams or more of mammalian excreta per pound. 
REMARKS: 
Since the majority of spices are imported, determine that the lot in question has not been 
previously examined and released by FDA as an import. If the lot has been examined and 
released previously, submit all available facts to CFSAN/Office of *Compliance*/Division of 
Enforcement (HFS-605) for seizure consideration in the usual manner. 
SPECIMEN CHARGE: 
Article fennel seed adulterated (when introduced into and while in interstate commerce)(while 
held for sale after shipment in interstate commerce), within meaning of 21 U.S.C. 342(a)(3), in 
that it consists wholly or in part of a filthy substance by reason of presence therein of (insects), 
(insect webbing), (insect excreta), (insect damaged fennel seed) and (mammalian excreta). 
*Materials between asterisks are new or revised* 
Issued: 10/1/80 
Revised: 3/95, 5/05 
Updated: 11/29/05
CPG Sec. 525.375 Whole Ginger - Adulteration 
with Insect Filth; Mold; Mammalian Excreta 
REGULATORY ACTION GUIDANCE: 
The following represents criteria for direct reference seizure *requests to the Office of Human 
and Animal Food Operations (OHAFO) in consultation with the Office of Enforcement and 
Import Operations (OEIO) and CFSAN, and for direct citation by the appropriate Field Office 
within the Human and Animal Food Program*: 
1.  Insect Filth and Mold:  
The ginger contains an average of 3% or more moldy and/or insect infested pieces by weight. 
or 
2.  Mammalian Excreta:  
The ginger contains an average of 3 milligrams or more of mammalian excreta per pound. 
REMARKS: 
Since the majority of spices are imported, determine that the lot in question has not been 
previously examined and released by FDA as an import. If the lot has been examined and 
released previously, submit all available facts to CFSAN/Office of *Compliance*/Division of 
Enforcement (HFS-605) for seizure consideration in the usual manner. 
SPECIMEN CHARGE: 
Article whole ginger, adulterated (when introduced into and while in interstate commerce)(while 
held for sale after shipment in interstate commerce), within meaning of 21 U.S.C. 342(a)(3), in 
that it consists wholly or in part of a filthy substance by reason of presence therein of (insects), 
(insect webbing), (insect excreta), (insect damaged whole ginger), and (mammalian excreta); and 
that it consists in part of a decomposed substance by reason of presence therein of (moldy, 
decomposed ginger). 
*Material between asterisks is new or revised.* 
Issued: 10/1/80 
Revised: 3/95, 5/05 
Updated: 11/29/05
CPG Sec. 525.500 Leafy Spices, Other than Bay 
Leaves - Whole Oregano Leaves, Whole 
Marjoram, Whole Sage Leaves and Whole 
Thyme Leaves - Adulteration with Insect Filth; 
Mold; Mammalian Excreta 
REGULATORY ACTION GUIDANCE: 
The following represents criteria for direct reference seizure *requests to the Office of Human 
and Animal Food Operations (OHAFO) in consultation with the Office of Enforcement and 
Import Operations (OEIO) and CFSAN, and for direct citation by the appropriate Field Office 
within the Human and Animal Food Program*: 
1.  Insect Filth and Mold:  
The spice contains an average of 5% or more insect infested and/or moldy pieces by weight. 
or 
2.  Mammalian Excreta:  
The spice contains an average of 1 milligram or more of mammalian excreta per pound, after 
processing (mammalian excreta should be identified as to source when possible). 
REMARKS: 
Since the majority of spices are imported, determine that the lot in question has not been 
previously examined and released by FDA as an import. If the lot has been examined and 
released previously, submit all available facts to CFSAN/Office of *Compliance*/Division of 
Enforcement (HFS-605) for seizure consideration in the usual manner. 
SPECIMEN CHARGE: 
Article (Leafy Spices (name specific spice)) adulterated (when introduced into and while in 
interstate commerce) (while held for sale after shipment in interstate commerce), within meaning 
of 21 U.S.C. 342(a)(3), in that it consists wholly or in part of a filthy substance by reason of 
presence therein of (insects), (insect webbing), (insect excreta), (insect damaged spice), and 
(mammalian excreta) and in that it consists in part of a decomposed substance by reason of 
presence therein of (moldy, decomposed spice).  NOTE: Only use direct citation authority when prosecution is anticipated and evidence to 
support a prosecution is included with the adulteration charge. Evidence necessary to support a 
prosecution is specified in existing regulatory procedures issuances. 
*Material between asterisks in new or revised.* 
Issued: 10/1/80 
Revised: 2/1/86, 3/95, 5/05 
Updated: 11/29/05
CPG Sec. 525.550 Mace - Adulteration with 
Insect Filth; Mold; Foreign Matter; Mammalian 
Excreta 
REGULATORY ACTION GUIDANCE: 
The following represents the criteria for direct reference seizure *request to the Office of Human 
and Animal Food Operations (OHAFO) in consultation with the Office of Enforcement and 
Import Operations (OEIO) and CFSAN, and for direct citation by the appropriate Field Office 
within the Human and Animal Food Program*: 
1.  Insect Filth and Mold: 
The mace contains an average of 3% or more insects infested and/or moldy pieces by 
weight; 
or 
2.  Mammalian Excreta: 
The mace contains an average of 3 or more milligrams of excreta per pound; 
or 
3.  Foreign Matter: 
The mace contains an average of 1.5% or more foreign matter through a 20-mesh sieve. 
REMARKS: 
Since the majority of spices are imported, determine that the lot in question has not been 
previously examined and released by FDA as an import. If the lot has been examined and 
released previously, submit all available facts to CFSAN/Office of *Compliance*/Division of 
Enforcement (HFS-605) for seizure consideration in the usual manner. 
SPECIMEN CHARGE: 
Article (mace) adulterated (when introduced into and while in interstate commerce)(while held 
for sale after shipment in interstate commerce), within meaning of 21 U.S.C. 342(a)(3), in that it 
consists wholly or in part of a filthy substance by reason of presence therein of (insects), (insect 
webbing), (insect excreta), (insect damaged mace), and (mammalian excreta); and that it consists 
in part of a decomposed substance by reason of presence therein of (moldy, decomposed mace); 
and is unfit for food by reason of presence therein of (stones), (clay), and (sand); or 342(b)(2) in 
that (stones), (clay), and (sand) have been substituted wholly or in part for mace.  *Material between asterisks is new or revised.* 
Issued: 10/1/80 
Revised: 3/95, 5/05 
Updated: 11/29/05
CPG Sec. 525.600 Whole and Ground Nutmeg - 
Adulteration with Insect Filth; Mold; Rodent 
Filth 
REGULATORY ACTION GUIDANCE: 
1.  The following represents the criteria for direct reference seizure *requests to the Office of 
Human and Animal Food Operations (OHAFO) in consultation with the Office of 
Enforcement and Import Operations (OEIO) and CFSAN, and for direct citation by the 
appropriate Field Office within the Human and Animal Food Program*:  
Whole Nutmeg 
The whole nutmeg contains an average of 10% or more insect infested and/or moldy pieces by 
count. 
2.  The following represents the criteria for recommending legal action to CFSAN/Office of 
*Compliance*/Division of Enforcement (HFS-605):  
Ground Nutmeg 
The nutmeg powder contains an average of 100 or more insect fragments, or the average of 
rodent hairs is 1 or more per 10 gram sample. 
NOTE: Determination for all defects are made on a minimum of six (6) subsamples; 10 gram 
subsamples for ground nutmeg and 100 nuts by count subsamples for whole nutmeg. 
REMARKS: 
Since the majority of spices are imported, determine that the lot in question has not been 
previously examined and released by FDA as an import. If the lot has been examined and 
released previously, submit all available facts to CFSAN/Office of *Compliance*/Division of 
Enforcement (HFS-605) for seizure consideration in the usual manner. 
SPECIMEN CHARGE: 
Article (whole/ground nutmeg) adulterated (when introduced into and while in interstate 
commerce)(while held for sale after shipment in interstate commerce), within meaning of 21 
U.S.C. 342(a)(3), in that it consists wholly or in part of a filthy substance by reason of presence 
therein of (insects), (insect webbing), (insect excreta), (insect fragments), (insect damaged 
nutmeg), and (rodent hairs); and that it consists in part of a decomposed substance by reason of 
presence therein of (moldy, decomposed nutmeg).  *Material between asterisks is new or revised.* 
Issued: 10/1/80 
Revised: 2/1/86, 3/95, 5/05 
Updated: 11/29/05
CPG Sec. 525.625 Whole and Ground Pepper - 
Adulteration with Insect & Rodent Filth; Mold; 
Mammalian Excreta; Foreign Matter 
REGULATORY ACTION GUIDANCE: 
1.  The following represents the criteria for direct reference seizure *requests to the Office of 
Human and Animal Food Operations (OHAFO) in consultation with the Office of 
Enforcement and Import Operations (OEIO) and CFSAN, and for direct citation by the 
appropriate Field Office within the Human and Animal Food Program*:  
Whole Pepper 
a.  Insect Filth and Mold  
The pepper contains an average of 1% or more insect infested and/or moldy pieces by weight. 
or 
b.  Mammalian Excreta  
The pepper contains an average of 1 milligram or more of mammalian excreta per pound. 
or 
c.  Foreign Matter  
The pepper contains an average of 1% or more pickings and siftings by weight. 
2.  The following represents criteria for recommending legal action to CFSAN/Office of 
*Compliance*/Division of Enforcement (HFS-605):  
Ground Pepper 
a.  Insect Filth  
The ground pepper in six or more subsamples contains an average of 475 or more insect 
fragments per 50 grams. 
or 
b.  Rodent Filth   The ground pepper in six or more subsamples contains an average of 2 or more rodent hair 
fragments per 50 grams. 
REMARKS: 
Since the majority of spices are imported, determine that the lot in question has not been 
previously examined and released by FDA as an import. If the lot has been examined and 
released previously, submit all available facts to CFSAN/Office of *Compliance*/Division of 
Enforcement (HFS-605) for seizure consideration in the usual manner. 
SPECIMEN CHARGE: 
Article (whole/ground pepper) adulterated (when introduced into and while in interstate 
commerce) (while held for sale after shipment in interstate commerce), within meaning of 21 
U.S.C. 342(a)(3), in that it consists wholly or in part of a filthy substance by reason of presence 
therein of (insects), (insect webbing), (insect excreta), (insect fragments), (insect damaged 
pepper), and (mammalian excreta), (rodent hairs); and that it consists in part of a decomposed 
substance by reason of presence therein of (moldy, decomposed pepper); and is unfit for food by 
reason of presence therein of (stones), (clay), and (sand); or 342(b)(2) in that (stones), (clay), and 
(sand) have been substituted wholly or in part for (whole/ground) pepper. 
*Material between asterisks is new or revised.* 
Issued: 10/1/80 
Revised: 2/1/86, 3/95, 5/05 
Updated: 11/29/05
CPG Sec. 525.700 Sesame Seeds - Adulteration 
with Insect Filth; Decomposition; Mammalian 
Excreta; Foreign Matter 
REGULATORY ACTION GUIDANCE: 
The following represents the criteria for direct reference seizure *requests to the Office of 
Human and Animal Food Operations (OHAFO) in consultation with the Office of Enforcement 
and Import Operations (OEIO) and CFSAN, and for direct citation by the appropriate Field 
Office within the Human and Animal Food Program*: 
1.  Insect Filth and Decomposition  
The sesame seeds contain an average of 5% or more insect infested or decomposed seeds by 
weight; 
or 
2.  Mammalian Excreta  
The sesame seeds contain an average of 5 milligrams or more of excreta per pound; 
or 
3.  Foreign Matter  
The sesame seeds contain an average of 0.5% or more foreign matter by weight. 
REMARKS: 
Since the majority of spices are imported, determine that the lot in question has not been 
previously examined and released by FDA as an import. If the lot has been examined and 
released previously, submit all available facts to CFSAN/Office of *Compliance*/Division of 
Enforcement (HFS-605) for seizure consideration in the usual manner. 
SPECIMEN CHARGE: 
Article (sesame seeds) adulterated (when introduced into and while in interstate 
commerce)(while held for sale after shipment in interstate commerce), within meaning of 21 
U.S.C. 342(a)(3), in that it consists wholly or in part of a filthy substance by reason of presence 
therein of (insects), (insect webbing), (insect excreta), (insect damaged sesame seeds), and 
(mammalian excreta); and that it consists in part of a decomposed substance by reason of 
presence therein of (moldy, decomposed sesame seeds); and is unfit for food by reason of  presence therein of (stones), (clay), and (sand); or 342(b)(2) in that (stones), (clay), and (sand) 
have been substituted wholly or in part for sesame seeds. 
*Material between asterisks is new or revised.* 
Issued: 10/1/80 
Revised: 3/95, 5/05 
Updated: 11/29/05
CPG Sec. 525.850 Whole Plant (Unprocessed) 
Oregano, Crushed Oregano & Ground Oregano 
- Adulteration by Insect & Rodent Filth; Mold; 
Mammalian Excreta 
REGULATORY ACTION GUIDANCE: 
1.  The following represents criteria for direct reference seizure *requests to the Office of 
Human and Animal Food Operations (OHAFO) in consultation with the Office of 
Enforcement and Import Operations (OEIO) and CFSAN, and for direct citation by the 
appropriate Field Office within the Human and Animal Food Program*: 
2.  Whole Plant (Unprocessed) Oregano: 
a.  Insect Filth and Mold: 
The spice contains an average of 5% or more insect infested and/or moldy pieces by weight. 
or 
b.  Mammalian Excreta: 
The spice contains an average of 1 milligram or more of mammalian excreta per pound 
(mammalian excreta should be identified as to source when possible). 
3.  The following represents the criteria for recommending legal action to CFSAN/Office of 
*Compliance*/Division of Enforcement (HFS-605).  
a.  Ground Oregano 
The ground oregano contains an average of 1250 or more insect fragments and/or an average of 5 
or more rodent hairs per 10 gram subsample. 
b.  Crushed Oregano 
The crushed oregano contains an average of 300 or more insect fragments and/or an average of 2 
or more rodent hairs per 10 gram subsample. 
NOTE: Determinations for all defects are made on a minimum of six (6) ten (10) gram 
subsamples for ground and crushed oregano. See Macroanalytical Procedures Manual for 
number of grams of subsamples used in analyses of whole spices. 
REMARKS:  Since the majority of spices are imported, determine that the lot in question has not been 
previously examined and released by FDA as an import. If the lot has been examined and 
released previously, submit all available facts to CFSAN/Office of *Compliance*/Division of 
Enforcement (HFS-605) for seizure consideration in the usual manner. 
SPECIMEN CHARGES (for all including leafy spices): 
Article (whole plant unprocessed/crushed/ground oregano) adulterated (when introduced into 
and while in interstate commerce) (while held for sale after shipment in interstate commerce) 
within meaning of 21 U.S.C. 342(a)(3), in that it consists wholly or in part of a filthy substance 
by reason of presence therein of (insects), (insect fragments), (insect webbing), (insect excreta), 
(insect damaged oregano), (mammalian excreta) and (rodent hairs); and that it consists in part of 
a decomposed substance by reason of the presence therein of (moldy, decomposed oregano) 
(mold). 
NOTE: Only use direct citation authority when prosecution is anticipated and evidence to 
support a prosecution is included with the adulteration charge. Evidence necessary to support a 
prosecution is specified in existing regulatory procedures issuances. 
*Material between asterisks is new or revised.* 
Issued: 2/01/86 
Revised: 3/95, 5/05 
Updated: 11/29/05