Shingles (Zoster) Vaccine (patient information)

# What is shingles
Shingles is a painful skin rash, often with blisters. It is also called Herpes Zoster. A shingles rash usually appears on one side of the face or body and lasts from 2 to 4 weeks. Its main symptom is pain, which can be quite severe. Other symptoms of shingles can include fever, headache, chills and upset stomach. Very rarely, a shingles infection can lead to pneumonia, hearing problems, blindness, brain inflammation (encephalitis) or death.
For about 1 person in 5, severe pain can continue even after the rash clears up. This is called post-herpetic neuralgia.
Shingles is caused by the Varicella Zoster virus, the same virus that causes chickenpox. Only someone who has had a case of chickenpox, or gotten chickenpox vaccine, can get shingles. The virus stays in your body. It can reappear many years later to cause a case of shingles.
You can't catch shingles from another person with shingles. However, a person who has never had chickenpox (or chickenpox vaccine) could get chickenpox from someone with shingles. This is not very common.
Shingles is far more common in people 50 and older than in younger people. It is also more common in people whose immune systems are weakened because of a disease such as cancer, or drugs such as steroids or chemotherapy. At least 1 million people a year in the United States get shingles.

# Shingles vaccine
A vaccine for shingles was licensed in 2006. In clinical trials, the vaccine prevented shingles in about half of people 60 years of age and older. It can also reduce the pain associated with shingles.
A single dose of shingles vaccine is indicated for adults 60 years of age and older.

# Which people should not get shingles vaccine or should wait
A person should not get shingles vaccine who:
- has ever had a life-threatening allergic reaction to gelatin, the antibiotic neomycin, or any other component of shingles vaccine. Tell your doctor if you have any severe allergies.
- has a weakened immune system because of HIV/AIDS or another disease that affects the immune system; treatment with drugs that affect the immune system, such as steroids; cancer treatment such as radiation or chemotherapy; a history of cancer affecting the bone marrow or lymphatic system, such as leukemia or lymphoma.
- has active, untreated tuberculosis.
- is pregnant, or might be pregnant. Women should not become pregnant until at least three months after getting shingles vaccine.
Someone with a minor illness, such as a cold, may be vaccinated. But anyone who is moderately or severely ill should usually wait until they recover before getting the vaccine. This includes anyone with a temperature of 101.3F or higher.

# What are the risks from shingles vaccine
A vaccine, like any medicine, could possibly cause serious problems, such as severe allergic reactions. However, the risk of a vaccine causing serious harm, or death, is extremely small. No serious problems have been identified with shingles vaccine. Like all vaccines, shingles vaccine is being closely monitored for unusual or severe problems.

## Mild Problems
- Redness, soreness, swelling, or itching at the site of the injection (about 1 person in 3).
- Headache (about 1 person in 70).

# What if there is a moderate or severe reaction
What should I look for?
Any unusual condition, such as a high fever or behavior changes. Signs of a serious allergic reaction can include difficulty breathing, hoarseness or wheezing, hives, paleness, weakness, a fast heart beat or dizziness. These usually occur within the first few hours after vaccination.
What should I do?
- Call a doctor, or get the person to a doctor right away.
- Tell your doctor what happened, the date and time it happened, and when the vaccination was given.
- Ask your health care provider to file a Vaccine Adverse Event Reporting System (VAERS) form if you have any reaction to the vaccine. Or call VAERS yourself at 1-800-822-7967, or visit their website at .

# The National Vaccine Injury Compensation Program
In the rare event that you or your child has a serious reaction to a vaccine, a federal program has been created to help pay for the care of those who have been harmed.
For details about the National Vaccine Injury Compensation Program, call 1-800-338-2382 or visit the program's website at .

# How can I learn more
- Ask your doctor or other health care provider. They can give you the vaccine package insert or suggest other sources of information.
- Call your local or state health department's immunization program.
- Contact the Centers for Disease Control and Prevention (CDC): call 1-800-232-4636 (1-800-CDC-INFO) or visit the National Immunization Program's website at 
Shingles (Zoster) Vaccine Information Statement. U.S. Department of Health and Human Services/Centers for Disease Control and Prevention National Immunization Program. 9/11/2006.

# Brand names of combination products
- containing