Clotrimazole (mucous membrane)

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# Overview
Clotrimazole (mucous membrane) is an azole antifungal that is FDA approved for the treatment of tinea pedis, tinea cruris and tinea corporis.   Common adverse reactions include nausea and vomiting.

# Adult Indications and Dosage

## FDA-Labeled Indications and Dosage (Adult)

### Anti-Fungal
- Dosing information
- Clean the affected area and dry thoroughly. Apply a thin layer of the product over affected area twice daily (morning and night) or as directed by a doctor. Supervise children in the use of this product. For athlete's foot: Pay special attention to spaces between the toes; wear well-fitting, ventilated shoes, and change shoes and socks at least once daily. For athlete's foot and ringworm, use daily for 4 weeks; for jock itch, use daily for 2 weeks. If condition persists longer, consult a doctor. This product is not effective on the scalp or nails.

## Off-Label Use and Dosage (Adult)

### Guideline-Supported Use
- There is limited information regarding Off-Label Guideline-Supported Use of clotrimazole in adult patients.

### NonGuideline-Supported Use

### Candidal vulvovaginitis
- Dosing information
- 0.5 grams administered once weekly for 2 weeks

# Pediatric Indications and Dosage

## FDA-Labeled Indications and Dosage (Pediatric)
- There is limited information regarding FDA-Labeled Use of Clotrimazole (mucous membrane) in pediatric patients.

## Off-Label Use and Dosage (Pediatric)

### Guideline-Supported Use
- There is limited information regarding Off-Label Guideline-Supported Use of clotrimazole in pediatric patients.

### NonGuideline-Supported Use
- There is limited information regarding Off-Label NonGuideline-Supported Use of clotrimazole in pediatric patients.

# Contraindications
Hypersensitivity to clotrimazole.

# Warnings
- For exteranl use only.
- If swallowed, get medical help or contact a Poison Control Center right away.
- Do not use on children under 2 years of age unless directed by a doctor.
- Avoid contact with the eyes.
- If irritation occurs or if there is no improvement within 2 weeks, discontinue use and consult a doctor.
- Keep out of reach of children

# Adverse Reactions

## Clinical Trials Experience
- Common gastrointestinal: nausea, vomiting.

## Postmarketing Experience
- FDA package insert for clotrimazole contains no information regarding Post marketing experience.

# Drug Interactions
There is limited information regarding Clotrimazole (mucous membrane) Drug Interactions in the drug label.

# Use in Specific Populations

### Pregnancy
Pregnancy Category (FDA): 
There is no FDA guidance on usage of Clotrimazole (mucous membrane) in women who are pregnant.
Pregnancy Category (AUS): 
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Clotrimazole (mucous membrane) in women who are pregnant.

### Labor and Delivery
- There is no FDA guidance on use of Clotrimazole (mucous membrane) during labor and delivery.

### Nursing Mothers
- There is no FDA guidance on the use of Clotrimazole (mucous membrane) with respect to nursing mothers.

### Pediatric Use
- There is no FDA guidance on the use of Clotrimazole (mucous membrane) with respect to pediatric patients.

### Geriatic Use
- There is no FDA guidance on the use of Clotrimazole (mucous membrane) with respect to geriatric patients.

### Gender
- There is no FDA guidance on the use of Clotrimazole (mucous membrane) with respect to specific gender populations.

### Race
- There is no FDA guidance on the use of Clotrimazole (mucous membrane) with respect to specific racial populations.

### Renal Impairment
- There is no FDA guidance on the use of Clotrimazole (mucous membrane) in patients with renal impairment.

### Hepatic Impairment
- There is no FDA guidance on the use of Clotrimazole (mucous membrane) in patients with hepatic impairment.

### Females of Reproductive Potential and Males
- There is no FDA guidance on the use of Clotrimazole (mucous membrane) in women of reproductive potentials and males.

### Immunocompromised Patients
- There is no FDA guidance one the use of Clotrimazole (mucous membrane) in patients who are immunocompromised.

# Administration and Monitoring

### Administration
- For exteranl use only.

### Monitoring
- FDA package insert for clotrimazole contains no information regarding drug monitoring.

# IV Compatibility
- There is limited information about the IV compatibility.

# Overdosage
There is limited information regarding Clotrimazole (mucous membrane) overdosage.  If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.

# Pharmacology

## Mechanism of Action
There is limited information regarding Clotrimazole (mucous membrane) Mechanism of Action in the drug label.

## Structure
There is limited information regarding Clotrimazole (mucous membrane) Structure in the drug label.

## Pharmacodynamics
- There is limited information regarding Pharmacodynamics of Clotrimazole (mucous membrane) in the drug label.

## Pharmacokinetics
- There is limited information regarding Pharmacokinetics of Clotrimazole (mucous membrane) in the drug label.

## Nonclinical Toxicology
- There is limited information regarding Nonclinical Toxicology of Clotrimazole (mucous membrane) in the drug label.

# Clinical Studies
- There is limited information regarding Clinical Studies of Clotrimazole (mucous membrane) in the drug label.

# How Supplied
There is limited information regarding Clotrimazole (mucous membrane) How Supplied in the drug label.

## Storage
There is limited information regarding Clotrimazole (mucous membrane) Storage in the drug label.

# Images

## Drug Images

## Package and Label Display Panel

# Patient Counseling Information
- There is limited information regarding Patient Counseling Information of Clotrimazole (mucous membrane) in the drug label.

# Precautions with Alcohol
- Alcohol-Clotrimazole interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

# Brand Names
3 Day Vaginal Cream
Clotrim Antifungal
Cruex Prescription Strength
Gyne-Lotrimin
Gyne-Lotrimin 3
Lotrimin
Lotrimin AF
Mycelex

# Look-Alike Drug Names
There is limited information regarding Clotrimazole (mucous membrane) Look-Alike Drug Names in the drug label.

# Drug Shortage Status

# Price