Persius/hicric huggingface dataset:
Improving the quality of pediatric clinical practice guidelines in China: a long way to go

 [bib_ref] Pediatric guidelines on medication: status, challenge and opportunities (in Chinese), Zhang [/bib_ref] [bib_ref] Motivations and training needs of general practitioner preceptors, Ren [/bib_ref] [bib_ref] Clinical practice guidelines in China, Yaolong [/bib_ref] [bib_ref] Quality of pediatric clinical practice guidelines, Liu [/bib_ref] [fig_ref] Table 1: AGREE II scores in different domains of CPGs with different characteristics [/fig_ref] [bib_ref] Analysis of clinical guidelines developed based on evidence in China, Wei [/bib_ref] [bib_ref] Guidelines international network: toward international standards for clinical practice guidelines, Qaseem [/bib_ref] 

# Funding
The work is supported by a grant from the Beijing Municipal Administration of Hospitals Incubating Program (No.PZ2019030).
[table] Table 1: AGREE II scores in different domains of CPGs with different characteristics. * More than three types.  It does not belong to the above types, such as management, rehabilitation, etc.  More than two types of formulating institution.AGREE II: Appraisal of Guidelines for REsearch & Evaluation II; CPGs: Clinical practice guidelines; TCM: Traditional Chinese medicine. [/table]
The CanPain SCI clinical practice guidelines for rehabilitation management of neuropathic pain after spinal cord injury: 2021 update



## Neuropathic nociceptive

## At-level neuropathic below-level neuropathic other neuropathic
Electric shock, shooting, squeezing, burning pain. Segmental pattern, located at NLI and/or within 3 dermatomes, or involves cauda equina Electric shock, shooting, squeezing, burning pain. Located more than 3 dermatomes below NLI (but may include them) Neuropathic pain indirectly related or unrelated to SCI, such as carpal tunnel syndrome, postherpetic neuralgia
[formula] + + + _ _ General Treatment Principles G1. [/formula]
Those with NP after SCI should be encouraged to pursue self-management strategies that they find beneficial for pain intensity reduction, coping with pain, and improving functional abilities.

## G2.
A comprehensive pain management strategy should address issues with activity, sleep, and mood that result from, or may worsen, pain. This could include both pharmacologic and non-pharmacologic strategies, as appropriate.
G3. Consider referral for specialized expert multidisciplinary SCI rehabilitation management to address functional limitations. (activity, mood, sleep).
G4. An interdisciplinary pain program that may consist of patient education, CBT, self-management strategies, group discussions, exercise, or guided relaxation could be considered in those with SCI and NP.
G5. CBT could be considered to improve coping skills and reduce pain interference.
Action Against Illegal Dental Practice



## Action against illegal dental practice [1]
 Vienna Austria September, 2009 Singapore One of the four FDI Mission Statements is: "To promote optimal oral and general health for all peoples".
In the interest of the oral and general health of the population, dental authorities and associations should insist that the practice of dentistry should only be carried out by those who are legally qualified to do so and after successful completion of appropriate dental education and training.
A prerequisite for achieving optimal oral health is for all people to have access to the best possible oral health care. Therefore, FDI recommends that appropriate Governmental agencies of all countries legally regulate the practice of dentistry, based on the principles of self-regulation and competent authority. Only those with the specific education, training and qualifications, recognized in each country, can be entrusted with the practice of dentistry.
The practice of dentistry by those not educationally and legally qualified should be opposed.
FDI recommends the competent authorities in each country to:
develop and establish a legal framework for the entire area of the practice of dentistry control the quality of the education and training for the practice of dentistry control the practice of dentistry within the established legal framework identify and suppress illegal dental practice

## Dental practice committee [2] classification: education [3] illegal dental practice [4] legislation [5]
Source URL: https://www.fdiworlddental.org/resources/policy-statements-and-resolutions/action-against-illegaldental-practice

## Links
[1] https://www.fdiworlddental.org/resources/policy-statements-and-resolutions/action-against-illegal-dental-practice [2] https://www.fdiworlddental.org/standing-committees/dental-practice-committee [3] https://www.fdiworlddental.org/policy-statement-classification/education [4] https://www.fdiworlddental.org/policy-statement-classification/illegal-dental-practice [5] https://www.fdiworlddental.org/policy-statement-classification/legislation
Guidelines for Developing and Reporting Machine Learning Predictive Models in Biomedical Research: A Multidisciplinary View



## Terms description

## Internal validation
Validation of model using data from the same source as training

## External validation
Validation of model using data from a source different from training

## Response variable
Variable to be predicted. Also known as dependent variable

## Independent variable
Variables used to predict the response variable.
Also known as feature The area under the ROC curve. It is often used to compare predictive models.
S ince the publication of a Canadian Paediatric Society position statement in 2011,(1) new evidence has been published showing that the risk of a severe allergic reaction following administration of the trivalent inactivated influenza vaccines (TIV) in egg-allergic patients is exceedingly low. Based on review of the recent literature,(2,3) including a study documenting lack of reaction to influenza vaccines in >4100 patients -including >500 with severe egg allergy -the CPS now recommends that all egg-allergic patients be vaccinated with a full dose of inactivated vaccine. There is no reason to believe that quadrivalent inactivated vaccine (QIV) would be less well tolerated than trivalent vaccine. Live attenuated influenza vaccine (LAIV) has not yet been evaluated in egg-allergic children and is not recommended at this time.(4)
The CPS endorses recommendations from the National Advisory Committee on Immunization for the 2014/2015 influenza season, including the following specific guidance: www. phac-aspc.gc.ca/naci-ccni/flu-grippe-eng.php:
- All clinics that administer vaccines need to have the expertise and equipment to be able to deal with anaphylaxis, as per the Public Health Agency of Canada's Canadian Immunization Guide.
- All egg-allergic patients should be vaccinated with a full dose of TIV or QIV unless they have previously had anaphylaxis from influenza vaccine. There is no need for split doses or prevaccination skin testing. Postvaccination monitoring should be the same as after any other vaccine.
- LAIV should not be used in egg-allergic patients because there are insufficient data to support a recommendation.
- The use and safety of LAIV should be studied in egg-allergic patients.
ACknoWLEDGEMEnTS: This update was reviewed by the Community Paediatrics Committee and Allergy Section executive of the Canadian Paediatric Society.

# Increasing the use of influenza vaccines in children with egg allergy
The OAML's Guidelines for the Collection and Storage of Specimens for Testing have been developed to provide practitioners with a clear and concise reference respecting the appropriate collection and storage of bacteriology specimens for testing in community laboratories. The guideline was developed by an expert group of laboratorians and has been reviewed and approved by the OAML's Quality Assurance of Clinical Laboratory Practice Committee. Specimen type and collection device will vary according to the testing methodology of the laboratory. Testing and treatment issues are addressed for the clinical condition listed. Good laboratory practice is influenced by clinical information. Laboratory procedures will be optimized in the presence of pertinent clinical information.#
The Ontario Association of Medical Laboratories (OAML) represents the community-based laboratory sector in Ontario. Its mission is to promote excellence in the provision of laboratory services and to contribute to shaping the future of health care in Ontario. The OAML encourages the highest level of professional and ethical integrity and technical excellence among laboratory owners, operators and staff in the provision of services to the benefit of the people of Ontario.

# OAML Community Laboratory Practice Guidelines
The OAML, through its Quality Assurance of Clinical Laboratory Practice Program, co-ordinates the development and dissemination, implementation and evaluation of guidelines for practitioners ordering laboratory testing from community laboratories.
A proposed guideline is developed by a working group of the Committee, usually with the participation of outside experts. The proposed guideline is submitted to the Committee as a whole, to laboratory Medical Directors and others for additional comment. The document is revised in light of these comments and submitted to the OAML Board for approval.
While generally applicable, OAML Guidelines are not a substitute for sound clinical judgement.
Approved guidelines are distributed to Community Laboratories and by them to their client physicians. The comments of end users are essential to the development of guidelines that will encourage adherence. You are strongly encouraged to submit your comments on this or any other OAML Guideline to:
# Guideline Resource Unit
The assessment, prevention, rehabilitation and management strategies outlined in this summary and accompanying guideline apply to adult cancer patients with advanced colorectal cancer. Refer to the full clinical practice guideline for a detailed description of the clinical questions, recommendations, guideline development methodology, and references.
This resource has been created to ensure the safe administration of panitumumab or cetuximab (anti-EGFR therapy) to patients with advanced colorectal cancer in Alberta.
# Guidelines for the Use of Serum Tests to Detect Renal Dysfunction
Serum creatinine and serum urea or blood urea nitrogen (BUN) are commonly ordered tests to detect renal dysfunction. Creatinine is the end product of creatine metabolism in muscle. Its formation and serum concentration are relatively constant. Urea is the end product of protein metabolism and its production and concentration vary with protein intake, enhanced tissue breakdown due to hemorrhage, trauma or use of corticosteroids and in liver disease.
Serum urea concentration is a less specific indicator of glomerular function than is serum creatinine. While a decrease in glomerular filtration rate (GFR) is associated with increases in both serum urea and serum creatinine, serum urea concentrations may vary independent of the GFR. A rise in serum creatinine concentrations almost always represents a reduction in GFR.
As muscle mass may be reduced in the frail, malnourished or extremely elderly, creatinine production may be correspondingly reduced; serum creatinine may not rise above the standard reference range even as the GFR is reduced.
In specific clinical situations, listed below, selective ordering of serum urea alone or of serum urea and creatinine simultaneously may be indicated:
- acute renal failure - prerenal failure - renal dialysis - chronic renal failure - GI bleeding - drug interference - hyperosmolar conditions - nutritional status
Serum creatinine should be used routinely to assess glomerular function. Routine ordering of serum creatinine and serum urea simultaneously is not recommended. Selective ordering of serum urea alone or of both serum urea and serum creatinine is useful in the appropriate clinical setting.
The Ontario Association of Medical Laboratories' (OAML) guidelines are intended to provide community physicians with information on the appropriate use of Erythrocyte Sedimentation Rate (ESR) tests. The guidelines represent the consensus thinking of a panel of experts in the field. Guidelines are, by their nature, general in focus and cannot apply in every clinical situation. They do not serve as a substitute for sound clinical judgement. These guidelines are appropriate at the time of writing and are applicable in most clinical situations.# Background
The Erythrocyte Sedimentation Rate (ESR) is a laboratory test which should be ordered in only a few clinical situations.
There is no evidence to support the use of the ESR as a screening test in asymptomatic individuals. The test should not be ordered in this situation.
Evaluation of the ESR is accepted as a diagnostic adjunct in Temporal Arteritis and Polymyalgia Rheumatica and may be used to monitor the activity of these conditions.
The ESR is a component of some clinical indices of Rheumatoid Arthritis and may be used to follow the activity of this condition or other connective tissue disorders.
The ESR may be used to monitor patients with treated Hodgkin's Disease and to monitor certain infections such as Tuberculosis and Osteomyelitis.
Slightly elevated ESR results must be interpreted with caution, particularly in patients with negative physical examinations. Extensive diagnostic workups are not indicated.
A markedly elevated ESR is often present in patients with significant infectious, inflammatory and malignant disease but, is rarely the sole indicator of the presence of such diseases.
It is recommended that the ESR not be used as a screening test in asymptomatic patients.
In specific clinical situations, ESR is a relevant test for diagnosis and disease monitoring. Test results must be interpreted with caution.
Identification of chronic kidney disease in people with diabetes requires screening for proteinuria, as well as an assessment of serum creatinine converted into an estimated glomerular function rate (eGFR). - All individuals with chronic kidney disease should be considered at high risk for cardiovascular events and should be treated to reduce these risks. - The development and progression of renal damage in diabetes can be reduced and slowed through intensive glycemic control and optimization of blood pressure. Progression of chronic kidney disease in diabetes can also be slowed through the use of medications that disrupt the renin angiotensin aldosterone system.- The earlier that the signs and symptoms of chronic kidney disease in diabetes are detected, the better, as it will reduce the chance of progression to advanced kidney disease and the need for dialysis or transplant. - You should have your blood and urine tested annually for early signs of chronic kidney disease in diabetes. - If you are found to have signs of chronic kidney disease, your health-care provider may recommend lifestyle or medication changes to help delay more damage to your kidneys.- Check serum potassium and creatinine at baseline and within 1 to 2 weeks of initiation or titration of therapy AND during times of acute illness. - If potassium becomes elevated or creatinine increases by more than 30% from baseline, therapy should be reviewed and serum creatinine and potassium levels should be rechecked. - Mild-to-moderate stable hyperkalemia: - Counsel on a low-potassium diet. - If persistent, non-potassium-sparing diuretics and/or oral sodium bicarbonate (in those with a metabolic acidosis) should be considered. - Consider temporarily reducing or holding RAAS blockade (i.e. ACE inhibitor, ARB or DRI). - Severe hyperkalemia: - In addition to emergency management strategies, RAAS blockade should be held or discontinued.# Introduction
Diseases of the kidney are a common finding in people with diabetes, with up to one-half demonstrating signs of renal damage in their lifetime (1)(2)(3). Diabetes is the leading cause of kidney disease in Canada (4). Kidney disease can be a devastating complication, as it is associated with significant reductions in both length and quality of life (5,6). A variety of forms of chronic kidney disease (CKD) in diabetes can be seen, including diabetic nephropathy, ischemic nephropathy related to vascular disease, hypertensive nephrosclerosis, as well as other renal diseases that are unrelated to diabetes (7,8) (Figure 1). This chapter discusses how to screen for and diagnose CKD in people with diabetes, how to slow its progression, and the impact of CKD on other aspects of diabetes management.
A thorough literature review of systematic reviews, meta-analyses and clinical practice guidelines  was the starting point for this process. This document is based on a compilation of published evidence regarding best practice in assessment and management of tobacco use and dependence as well as review and feedback from local expert opinion.
After conducting this review, the WRHA Smoking Cessation Best Practice Working Group (SCBPWG) decided to adopt the 2011 Canadian Practice-Informed Smoking Cessation Guideline, 23 developed by The Canadian Action Network for the Advancement, Dissemination and Adoption of Practice-informed Tobacco Treatment (CAN-ADAPTT), as the foundation of its recommendations. The rationale for this is:
-Literature reviewed for the development of CAN-ADAPTT Guideline encompasses literature reviewed by SCBPWG -The CAN-ADAPTT Guideline is a Canadian product developed by interdisciplinary team, which included consultative processes -It is the most recent of all published guidelines -Recommendations in the CAN-ADAPTT Guideline are structured around the 5-A Model 24 for intervening with people who use tobacco -Use of the CAN-ADAPTT Guideline allows for one evidence grading system (see Appendix A) Part of the decision-making process was to compare the CAN-ADAPTT Guideline to the 2008 US Centre for Disease Control (CDC) Guideline, 16 which has generally been considered the gold-standard guideline for the treatment of tobacco use and dependence. These two guidelines were found to be very similar.

# How to Use This Guideline
This guideline is designed as a foundation that will support, rather than replace, the clinical judgment of health care providers. Some information in this guideline may be less applicable in certain situations, or with certain populations.
A number of sub-groups of the SCBPWG have developed evidence-based operational procedures and resources/tools to support implementation of this guideline and to provide context in the specific sectors and programs within the Region.
Please refer to Appendix A for description of grade of recommendation and level of evidence used by the CAN-ADAPTT Guideline. 23
Blood transfusion is an essential part of modern health care, and it helps to save millions of lives every year. National health authorities have a responsibility to ensure adequate blood supplies in a timely manner, to meet the needs of all patients requiring transfusion. The conditions under which blood and blood products are stored and transported have a direct effect on their safety, efficacy and availability. The blood cold chain is a system for storing and transporting blood and blood products, within the correct temperature range and conditions, from the point of collection from blood donors to the point of transfusion to the patient. Deviations from specified temperature ranges and conditions during storage and transportation of blood and blood products can seriously affect the viability of the constituents of blood, thus leading to reduced clinical benefits. It can also increase the risk of bacterial proliferation in blood components during storage and may cause potentially lifethreatening transfusion reactions, such as septic shock and even death. A break in the blood cold chain leads to wastage and discard of unsuitable blood units, which may adversely affect the supply of blood and blood products for transfusion.#
Implementation of WHO blood safety strategy in many countries has led to the consolidation of key operations (e.g. testing and processing) in selected, strategically located sites as well as the expansion of safe blood transfusion services to cover wider geographic areas. This situation requires frequent movement of blood, blood products and blood samples across different blood centres and hospitals. An effective blood cold chain is thus an important part of the strategy to promote universal access to safe blood transfusion.
The establishment of a reliable system for blood cold chain requires commitment and support of national health authorities and sustainable funding. This is best achieved in a blood transfusion service that is coordinated at different levels within the national health care system. Quality principles should apply to all aspects of the blood cold chain, in blood centres, in hospital blood banks and in all institutions handling blood, blood products and blood samples. Quality system should be established and implemented for effective management of blood cold chain, including equipment, personnel and procedures.

# Monitoring and evaluation
A well-designed system of monitoring and evaluation contributes to continuous improvement, and is essential for a blood cold chain that meets quality standards. Key activities include:  Monitoring of critical control points and indicators in the blood cold chain, such as discard rates of blood and blood products due to failure of specified conditions and temperature control  Evaluation of the improvements in the blood cold chain system  Inclusion of the blood cold chain in inspections, audits and regular assessment of blood centres and hospital blood banks  Remedial, corrective and preventive actions that lead to continuous improvement of the blood cold chain. Quality system embraces all aspects
Evidence and recommendation on antenatal multiple micronutrient supplements 7

# Dissemination and implementation of the recommendation 20
# Introduction W H O G U I D E L I N E S F O R I N D O O R A I R Q U A L I T Y: S E L E C T E D P O L L U TA N T S 2
burden of disease. This is a huge impact on health; indeed, far larger than that imposed by exposure to outdoor air pollutants.
Work on assessing the health effects of indoor air pollution has lagged behind that on outdoor air pollution for a number of reasons, including: the fact that policy development in the air pollution field has focused on outdoor air pollution as a result of the correctly perceived need to deal with the high levels of outdoor air pollutants associated with both coal smoke and photochemical smog; the ready applicability of standards to outdoor concentrations of air pollutants; the feasibility of monitoring concentrations of outdoor air pollutants on a large scale; the focus of epidemiologists on defining coefficients linking outdoor concentrations of air pollutants with effects on health; and the fact that the science and policy communities have focused on the public health impacts of air pollution in wealthy developed countries, while often disregarding the larger burden of disease due to indoor air pollution from solid fuel burning in the developing world.
Questions such as: "how could air quality standards be enforced indoors?" have delayed work on specific indoor air quality guidelines. However, WHO has not ignored the problem of indoor exposure to air pollutants and has stressed since the publication of the first edition of the guidelines in 1987 (1) that they should be applicable to both indoor and outdoor air. This was reinforced in the global update published in 2006 (3) and the guidelines were recommended for application in all microenvironments. It should be noted that the workplace has been specifically excluded: WHO air quality guidelines have not been seen as a basis for occupational exposure standards.

# Developing indoor air quality guidelines