Immunoglobulin superfamily genes
The immunoglobulin supergene family is "the group of proteins that have immunoglobulin-like domains, including histocompatibility antigens, the T-cell antigen receptor, poly-IgR, and other proteins involved in the vertebrate immune response (17)."

# Immunoglobulin supergene family

# Human genes
Gene ID: 682 is BSG basigin (Ok blood group) on 19p13.3: "The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene."
- NP_001309172.1 basigin isoform 2 precursor: "Transcript Variant: This variant (5), as well as variant 2, encodes isoform 2." Conserved Domains (1) summary: smart00410 Location: 112  202 IG_like; Immunoglobulin like.
- NP_001719.2 basigin isoform 1 precursor: "Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1)." Conserved Domains (3) summary: cd00096 Location: 40  114 Ig; Immunoglobulin domain, smart00410 Location: 228  318 IG_like; Immunoglobulin like, and cl11960 Location: 219  317 Ig; Immunoglobulin domain.
- NP_940991.1 basigin isoform 2 precursor: "Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Variants 2 and 5 both encode the same isoform (2)." Conserved Domains (1) summary: smart00410 Location: 112  202 IG_like; Immunoglobulin like.
- NP_940992.1 basigin isoform 3: "Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (3) is shorter at the N-terminus compared to isoform 1." Conserved Domains (2) summary: smart00410 Location: 19  109 IG_like; Immunoglobulin like and cl11960 Location: 10  108 Ig; Immunoglobulin domain.
- NP_940993.1 basigin isoform 4: "Transcript Variant: This variant (4) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (4) has a shorter and distinct N-terminus compared to isoform 1." Conserved Domains (2) summary: smart00410 Location: 48  138 IG_like; Immunoglobulin like and cl11960 Location: 39  137 Ig; Immunoglobulin domain.
- XP_016882662.1 basigin isoform X1 Conserved Domains (3) summary: cd00096 Location: 40  114 Ig; Immunoglobulin domain, smart00410 Location: 228  318 IG_like; Immunoglobulin like, and cl11960 Location: 219  317 Ig; Immunoglobulin domain.
Gene ID: 924 is CD7 CD7 molecule on 17q25.3: "This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development."
- NP_006128.1 T-cell antigen CD7 precursor, Conserved Domains (1) summary: pfam07686 Location: 31  132 V-set; Immunoglobulin V-set domain.
- XP_016880805.1 T-cell antigen CD7 isoform X1, Conserved Domains (2) summary: smart00410 Location: 1  31 IG_like; Immunoglobulin like and cl11960 Location: 1  32 Ig; Immunoglobulin domain.
- XP_011521910.1 T-cell antigen CD7 isoform X1, Conserved Domains (2) summary: smart00410 Location: 1  31 IG_like; Immunoglobulin like and cl11960 Location: 1  32 Ig; Immunoglobulin domain.
Gene ID: 1272 is CNTN1 contactin 1 on 12q12: "The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene."
- NP_001242992.1 contactin-1 isoform 3 precursor: "Transcript Variant: This variant (3) lacks several 3' exons and includes an alternate 3' terminal exon, compared to variant 1. The resulting isoform (3) is shorter and has a distinct C-terminus, compared to isoform 1. Variants 3 and 4 encode the same isoform 3." Conserved Domains (6) summary: cd05727 Location: 134  230 Ig2_Contactin-2-like; Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins, cd05849 Location: 40  132 Ig1_Contactin-1; First immunoglobulin (Ig) domain of contactin-1, cd05851 Location: 241  328 Ig3_Contactin-1; Third immunoglobulin (Ig) domain of contactin-1, cd05852 Location: 429  501 Ig5_Contactin-1; Fifth immunoglobulin (Ig) domain of contactin-1, cd04970 Location: 520  602 Ig6_Contactin; Sixth immunoglobulin (Ig) domain of contactin and cl11960 Location: 332  408 Ig; Immunoglobulin domain.
- NP_001242993.1 contactin-1 isoform 3 precursor: "Transcript Variant: This variant (4) differs in the 5' UTR, lacks several 3' exons and includes an alternate 3' terminal exon, compared to variant 1. The resulting isoform (3) is shorter and has a distinct C-terminus, compared to isoform 1. Variants 3 and 4 encode the same isoform 3." Conserved Domains (6) summary: cd05727 Location: 134  230 Ig2_Contactin-2-like; Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins, cd05849 Location: 40  132 Ig1_Contactin-1; First immunoglobulin (Ig) domain of contactin-1, cd05851 Location: 241  328 Ig3_Contactin-1; Third immunoglobulin (Ig) domain of contactin-1, cd05852 Location: 429  501 Ig5_Contactin-1; Fifth immunoglobulin (Ig) domain of contactin-1, cd04970 Location: 520  602 Ig6_Contactin; Sixth immunoglobulin (Ig) domain of contactin and cl11960 Location: 332  408 Ig; Immunoglobulin domain.
- NP_001834.2 contactin-1 isoform 1 precursor: "Transcript Variant: This variant (1) is the longest transcript and encodes the longest isoform (1)." Conserved Domains (10) summary: cd04970 Location: 520  601 Ig6_Contactin_like; Sixth Ig domain of contactin, cd05727 Location: 134  230 Ig2_Contactin-2-like; Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins, cd05849 Location: 40  132 Ig1_Contactin-1; First Ig domain of contactin-1, cd05851 Location: 241  328 Ig3_Contactin-1; Third Ig domain of contactin-1, cd05852 Location: 429  501 Ig5_Contactin-1; Fifth Ig domain of contactin-1 and smart00410 Location: 422  501 IG_like; Immunoglobulin like, pfam07679 Location: 331  408 I-set; Immunoglobulin I-set domain and cl11960 Location: 332  408 Ig; Immunoglobulin domain.
- NP_778203.1 contactin-1 isoform 2 precursor: "Transcript Variant: This variant (2) lacks an in-frame coding exon, compared to variant 1. The resulting isoform (2) lacks an internal segment in the N-terminal region, compared to isoform 1." Conserved Domains (10) summary: cd04970 Location: 509  590 Ig6_Contactin_like; Sixth Ig domain of contactin, cd05727 Location: 123  219 Ig2_Contactin-2-like; Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins, cd05849 Location: 29  121 Ig1_Contactin-1; First Ig domain of contactin-1, cd05851 Location: 230  317 Ig3_Contactin-1; Third Ig domain of contactin-1, cd05852 Location: 418  490 Ig5_Contactin-1; Fifth Ig domain of contactin-1, smart00410 Location: 411  490 IG_like; Immunoglobulin like, pfam07679 Location: 320  397 I-set; Immunoglobulin I-set domain, and cl11960,Location:,321  397 Ig; Immunoglobulin domain.
- XP_011536228.1 contactin-1 isoform X1, Conserved Domains (10) summary: cd04970 Location:  520  601 Ig6_Contactin_like; Sixth Ig domain of contactin, cd05727 Location: 134  230 Ig2_Contactin-2-like; Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins, cd05849 Location: 40  132 Ig1_Contactin-1; First Ig domain of contactin-1, cd05851 Location: 241  328 Ig3_Contactin-1; Third Ig domain of contactin-1, cd05852 Location: 429  501 Ig5_Contactin-1; Fifth Ig domain of contactin-1, smart00410 Location: 422  501 IG_like; Immunoglobulin like, pfam07679 Location: 331  408 I-set; Immunoglobulin I-set domain and cl11960 Location: 332  408 Ig; Immunoglobulin domain.
- XP_024304611.1 contactin-1 isoform X2, Conserved Domains (6) summary: cd05727 Location: 134  230 Ig2_Contactin-2-like; Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins, cd05849 Location: 40  132 Ig1_Contactin-1; First immunoglobulin (Ig) domain of contactin-1, cd05851 Location: 241  328 Ig3_Contactin-1; Third immunoglobulin (Ig) domain of contactin-1, cd05852 Location: 429  501 Ig5_Contactin-1; Fifth immunoglobulin (Ig) domain of contactin-1, cd04970 Location: 520  602 Ig6_Contactin; Sixth immunoglobulin (Ig) domain of contactin and cl11960 Location: 332  408 Ig; Immunoglobulin domain.
- XP_005268708.1 contactin-1 isoform X1, Conserved Domains (10) summary: cd04970 Location: 520  601 Ig6_Contactin_like; Sixth Ig domain of contactin, cd05727 Location: 134  230 Ig2_Contactin-2-like; Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins, cd05849 Location: 40  132 Ig1_Contactin-1; First Ig domain of contactin-1, cd05851 Location: 241  328 Ig3_Contactin-1; Third Ig domain of contactin-1, cd05852 Location: 429  501 Ig5_Contactin-1; Fifth Ig domain of contactin-1, smart00410 Location: 422  501 IG_like; Immunoglobulin like, pfam07679 Location: 331  408 I-set; Immunoglobulin I-set domain and cl11960 Location: 332  408 Ig; Immunoglobulin domain.
- XP_011536229.1 contactin-1 isoform X1, Conserved Domains (10) summary: cd04970 Location: 520  601 Ig6_Contactin_like; Sixth Ig domain of contactin, cd05727 Location: 134  230 Ig2_Contactin-2-like; Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins, cd05849 Location: 40  132 Ig1_Contactin-1; First Ig domain of contactin-1, cd05851 Location: 241  328 Ig3_Contactin-1; Third Ig domain of contactin-1, cd05852 Location: 429  501 Ig5_Contactin-1; Fifth Ig domain of contactin-1, smart00410 Location: 422  501 IG_like; Immunoglobulin like, pfam07679 Location: 331  408 I-set; Immunoglobulin I-set domain and cl11960 Location: 332  408 Ig; Immunoglobulin domain.
- XP_006719304.1 contactin-1 isoform X1, Conserved Domains (10) summary: cd04970 Location: 520  601 Ig6_Contactin_like; Sixth Ig domain of contactin, cd05727 Location: 134  230 Ig2_Contactin-2-like; Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins, cd05849 Location: 40  132 Ig1_Contactin-1; First Ig domain of contactin-1, cd05851 Location: 241  328 Ig3_Contactin-1; Third Ig domain of contactin-1, cd05852 Location: 429  501 Ig5_Contactin-1; Fifth Ig domain of contactin-1, smart00410 Location: 422  501 IG_like; Immunoglobulin like, pfam07679 Location: 331  408 I-set; Immunoglobulin I-set domain and cl11960 Location: 332  408 Ig; Immunoglobulin domain.
- XP_016874316.1 contactin-1 isoform X2, Conserved Domains (6) summary: cd05727 Location: 134  230 Ig2_Contactin-2-like; Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins, cd05849 Location: 40  132 Ig1_Contactin-1; First immunoglobulin (Ig) domain of contactin-1, cd05851 Location: 241  328 Ig3_Contactin-1; Third immunoglobulin (Ig) domain of contactin-1, cd05852 Location: 429  501 Ig5_Contactin-1; Fifth immunoglobulin (Ig) domain of contactin-1, cd04970 Location: 520  602 Ig6_Contactin; Sixth immunoglobulin (Ig) domain of contactin and cl11960 Location: 332  408 Ig; Immunoglobulin domain.
- XP_016874315.1 contactin-1 isoform X2, Conserved Domains (6) summary: cd05727 Location: 134  230 Ig2_Contactin-2-like; Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins, cd05849 Location: 40  132 Ig1_Contactin-1; First immunoglobulin (Ig) domain of contactin-1, cd05851 Location: 241  328 Ig3_Contactin-1; Third immunoglobulin (Ig) domain of contactin-1, cd05852 Location: 429  501 Ig5_Contactin-1; Fifth immunoglobulin (Ig) domain of contactin-1, cd04970 Location: 520  602 Ig6_Contactin; Sixth immunoglobulin (Ig) domain of contactin and cl11960 Location: 332  408 Ig; Immunoglobulin domain.
Gene ID: 2204 see Immunoglobulin like domain cd05751.
Gene ID: 3321 is IGSF3 immunoglobulin superfamily member 3 on 1p13.1: "The protein encoded by this gene is an immunoglobulin-like membrane protein containing several V-type Ig-like domains. A mutation in this gene has been associated with bilateral nasolacrimal duct obstruction (LCDD)."
- NP_001007238.1 immunoglobulin superfamily member 3 isoform 2 precursor: "Transcript Variant: This variant (2) differs in the 5' UTR and lacks an alternate in-frame exon, compared to variant 1. The encoded isoform (2) is shorter than isoform 1." Conserved Domains (4) summary: smart00406 Location: 163  247 IGv; Immunoglobulin V-Type, smart00410 Location: 687  810 IG_like; Immunoglobulin like, pfam07686 Location: 687  810 V-set; Immunoglobulin V-set domain, and cl11960 Location: 34  141 Ig; Immunoglobulin domain.
- NP_001533.2 immunoglobulin superfamily member 3 isoform 1 precursor: "Transcript Variant: This variant (1) encodes the longer isoform (1)." Conserved Domains (4) summary: smart00406 Location: 163  247 IGv; Immunoglobulin V-Type, smart00410 Location: 707  830 IG_like; Immunoglobulin like, and pfam07686 Location: 707  830 V-set; Immunoglobulin V-set domain, and cl11960 Location: 34  141 Ig; Immunoglobulin domain.
- XP_011539617.1 immunoglobulin superfamily member 3 isoform X2 Conserved Domains (4) summary: smart00406 Location: 163  247 IGv; Immunoglobulin V-Type, smart00410 Location: 707  830 IG_like; Immunoglobulin like, pfam07686 Location: 707  830 V-set; Immunoglobulin V-set domain, and cl11960 Location: 34  141 Ig; Immunoglobulin domain.
- XP_006710656.1 immunoglobulin superfamily member 3 isoform X1 Conserved Domains (4) summary: smart00406 Location: 168  252 IGv; Immunoglobulin V-Type, smart00410 Location: 712  835 IG_like; Immunoglobulin like, 'pfam07686 Location: 712  835 V-set; Immunoglobulin V-set domain, and cl11960  Location: 39  146 Ig; Immunoglobulin domain.
- XP_005270851.1 immunoglobulin superfamily member 3 isoform X3 Conserved Domains (4) summary: smart00406 Location: 168  252 IGv; Immunoglobulin V-Type, smart00410 Location: 692  815 IG_like; Immunoglobulin like, and pfam07686 Location: 692  815 V-set; Immunoglobulin V-set domain, and cl11960 Location: 39  146 Ig; Immunoglobulin domain.
- XP_011539618.1 immunoglobulin superfamily member 3 isoform X4 Conserved Domains (3) summary: smart00410 Location: 150  273 IG_like; Immunoglobulin like, pfam07686 Location: 150  273 V-set; Immunoglobulin V-set domain, and cl11960 Location: 284  395 Ig; Immunoglobulin domain.
Gene ID: 3476 is IGBP1 immunoglobulin binding protein 1 on Xq13.1: "The proliferation and differentiation of B cells is dependent upon a B-cell antigen receptor (BCR) complex. Binding of antigens to specific B-cell receptors results in a tyrosine phosphorylation reaction through the BCR complex and leads to multiple signal transduction pathways."
- NP_001357121.1 immunoglobulin-binding protein 1 isoform 1 .
- NP_001357122.1 immunoglobulin-binding protein 1 isoform 1 .
- NP_001357123.1 immunoglobulin-binding protein 1 isoform 2 .
- NP_001542.1 immunoglobulin-binding protein 1 isoform 1 .
Gene ID: 3547 is IGSF1 immunoglobulin superfamily member 1 on Xq26.1: "This gene encodes a member of the immunoglobulin-like domain-containing superfamily. Proteins in this superfamily contain varying numbers of immunoglobulin-like domains and are thought to participate in the regulation of interactions between cells. Multiple transcript variants encoding different isoforms have been found for this gene."
- NP_001164432.1 immunoglobulin superfamily member 1 isoform 3 precursor: "Transcript Variant: This variant (3) represents the longest transcript and encodes the longest protein (isoform 3)." Conserved Domains (2) summary: smart00410 Location: 793  873 IG_like; Immunoglobulin like and cl11960 Location: 1166  1252 Ig; Immunoglobulin domain.
- NP_001164433.1 immunoglobulin superfamily member 1 isoform 4: "Transcript Variant: This variant (4) lacks an alternate in-frame exon in the 5' coding region and uses an alternate in-frame splice site in a 3' exon compared to variant 3. The resulting protein (isoform 4) is shorter compared to isoform 3." Conserved Domains (2) summary: smart00410 Location: 779  859 IG_like; Immunoglobulin like and cl11960 Location: 1152  1238 Ig; Immunoglobulin domain.
- NP_001164434.1 immunoglobulin superfamily member 1 isoform 2 precursor: "Transcript Variant: This variant (5) differs in the 5' UTR, and 3' coding region and UTR compared to variant 3. The resulting protein (isoform 2) has a distinct C-terminus and is shorter than isoform 3. Variants 2 and 5 encode the same protein." Conserved Domains (2) summary: smart00410 Location: 142  200 IG_like; Immunoglobulin like and cl11960 Location: 130  222 Ig; Immunoglobulin domain.
- NP_001546.2 immunoglobulin superfamily member 1 isoform 1 precursor: "Transcript Variant: This variant (1) uses an alternate in-frame splice site in a 3' exon compared to variant 3. The resulting protein (isoform 1) is shorter compared to isoform 3." Conserved Domains (2) summary: smart00410 Location: 788  868 IG_like; Immunoglobulin like and cl11960 Location: 1161  1247 Ig; Immunoglobulin domain.
- NP_991402.1 immunoglobulin superfamily member 1 isoform 2 precursor: "Transcript Variant: This variant (2) differs in the 3' coding region and UTR compared to variant 3. The resulting protein (isoform 2) has a distinct C-terminus and is shorter than isoform 3. Variants 2 and 5 encode the same protein." Conserved Domains (2) summary: smart00410 Location: 142  200 IG_like; Immunoglobulin like and cl11960 Location: 130  222 Ig; Immunoglobulin domain.
- XP_011529632.1 immunoglobulin superfamily member 1 isoform X1, Conserved Domains (2) summary: smart00410 Location: 793  873 IG_like; Immunoglobulin like and cl11960 Location: 1166  1252 Ig; Immunoglobulin domain.
- XP_011529636.1 immunoglobulin superfamily member 1 isoform X3, Conserved Domains (2) summary: smart00410 Location: 793  873 IG_like; Immunoglobulin like and cl11960 Location: 974  1060 Ig; Immunoglobulin domain.
- XP_011529635.1 immunoglobulin superfamily member 1 isoform X2, Conserved Domains (2) summary: smart00410 Location: 793  873 IG_like; Immunoglobulin like and cl11960 Location: 1083  1169 Ig; Immunoglobulin domain.
Gene ID: 3671 is ISLR immunoglobulin superfamily containing leucine rich repeat on 15q24.1.
- NP_005536.1 immunoglobulin superfamily containing leucine-rich repeat protein precursor: "Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein." Conserved Domains (4) summary: cl28434 Location: 239  340 I-set; Immunoglobulin I-set domain.
- NP_958934.1 immunoglobulin superfamily containing leucine-rich repeat protein precursor: "Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein." Conserved Domains (4) summary: cl28434 Location: 239  340 I-set; Immunoglobulin I-set domain.
Gene ID: 9398 is CD101 CD101 molecule aka IGSF2 on 1p13.1.
- NP_001243035.1 immunoglobulin superfamily member 2 isoform 1 precursor: "Transcript Variant: This variant (2) uses an alternate splice site in the 3' UTR, compared to variant 1. Variants 1, 2 and 3 all encode isoform 1." Conserved Domains (2) summary: smart00410 Location: 87  142 IG_like; Immunoglobulin like and cl11960 Location: 19  142 Ig; Immunoglobulin domain.
- NP_001243038.1 immunoglobulin superfamily member 2 isoform 1 precursor: "Transcript Variant: This variant (3) uses an alternate splice site in the 3' UTR, compared to variant 1. Variants 1, 2 and 3 all encode isoform 1." Conserved Domains (2) summary: smart00410 Location: 87  142 IG_like; Immunoglobulin like and cl11960 Location: 19  142 Ig; Immunoglobulin domain.
- NP_001243040.1 immunoglobulin superfamily member 2 isoform 2 precursor: "Transcript Variant: This variant (4) uses an alternate in-frame splice site in the 5' coding region, and also an alternate splice site in the 3' UTR, compared to variant 1. The encoded isoform (2) is shorter than isoform 1." Conserved Domains (2) summary: smart00410 Location: 762  948 IG_like; Immunoglobulin like and cl11960 Location: 759  849 Ig; Immunoglobulin domain.
- NP_004249.2 immunoglobulin superfamily member 2 isoform 1 precursor: "Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Variants 1, 2 and 3 all encode isoform 1." Conserved Domains (2) summary: smart00410 Location: 87  142 IG_like; Immunoglobulin like and cl11960 Location: 19  142 Ig; Immunoglobulin domain.
- XP_024306770.1 immunoglobulin superfamily member 2 isoform X1, Conserved Domains (2) summary: smart00410 Location: 311  407 IG_like; Immunoglobulin like and cl11960 Location: 173  279 Ig; Immunoglobulin domain.
- XP_024306771.1 immunoglobulin superfamily member 2 isoform X1, Conserved Domains (2) summary: smart00410 Location: 311  407 IG_like; Immunoglobulin like and cl11960 Location: 173  279 Ig; Immunoglobulin domain.
- XP_024306773.1 immunoglobulin superfamily member 2 isoform X1, Conserved Domains (2) summary: smart00410 Location: 311  407 IG_like; Immunoglobulin like and cl11960 Location: 173  279 Ig; Immunoglobulin domain.
Gene ID: 9543 is IGDCC3 immunoglobulin superfamily DCC subclass member 3 on 15q22.31.
- NP_004875.2 immunoglobulin superfamily DCC subclass member 3 precursor, Conserved Domains (6) summary: cd00096 Location: 347  414 Ig; Immunoglobulin domain, smart00410 Location: 244  326 IG_like; Immunoglobulin like, pfam07679 Location: 331  417 I-set; Immunoglobulin I-set domain and cl11960 Location: 44  135 Ig; Immunoglobulin domain.
- XP_011520543.2  immunoglobulin superfamily DCC subclass member 3 isoform X3, Conserved Domains (5) summary: pfam07679 Location: 235  321 I-set; Immunoglobulin I-set domain, pfam13927 Location: 142  214 Ig_3; Immunoglobulin domain and cl11960 Location: 47  131 Ig; Immunoglobulin domain.
- XP_011520546.1 immunoglobulin superfamily DCC subclass member 3 isoform X2, Conserved Domains (6) summary: cd00096 Location: 210  277 Ig; Immunoglobulin domain, smart00410 Location: 107  189 IG_like; Immunoglobulin like, pfam07679 Location: 194  280 I-set; Immunoglobulin I-set domain and cl11960 Location: 6  90 Ig; Immunoglobulin domain.
- XP_011520545.1 immunoglobulin superfamily DCC subclass member 3 isoform X1, Conserved Domains (6) summary: cd00096 Location: 224  291 Ig; Immunoglobulin domain, smart00410 Location: 121  203 IG_like; Immunoglobulin like, pfam07679 Location: 208  294 I-set; Immunoglobulin I-set domain and cl11960 Location: 20  104 Ig; Immunoglobulin domain.
Gene ID: 10261 is IGSF6 immunoglobulin superfamily member 6 on 16p12.2.
- NP_005840.2 immunoglobulin superfamily member 6 precursor, Conserved Domains (2) summary: smart00410 Location: 45  141 IG_like; Immunoglobulin like and pfam07686 Location: 33  142 V-set; Immunoglobulin V-set domain.
Gene ID: 10871 is CD300C CD300c molecule aka IGSF16 on 17q25.1: "The CMRF35 antigen, which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes (Jackson et al., 1992 )."
- NP_006669.1 CMRF35-like molecule 6 precursor, Conserved Domains (2) summary: cd05716 Location: 30  119 Ig_pIgR_like; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR) and similar domains and cl11960 Location: 95  183 Ig; Immunoglobulin domain.
Gene ID: 11314 is CD300A CD300a molecule aka IGSF12 on 17q25.1: "This gene encodes a member of the CD300 glycoprotein family of cell surface proteins found on leukocytes involved in immune response signaling pathways. This gene is located on chromosome 17 in a cluster with all but one of the other family members. Multiple transcript variants encoding different isoforms have been found for this gene."
- NP_001243770.1 CMRF35-like molecule 8 isoform 2 precursor: "Transcript Variant: This variant (2) lacks an exon in the 5' coding region compared to variant 1. The resulting protein (isoform 2), also referred to as IRC1c, is shorter compared to isoform 1."
- NP_001317385.1 CMRF35-like molecule 8 isoform 3 .
- NP_001317386.1 CMRF35-like molecule 8 isoform 4 precursor .
- NP_009192.2 CMRF35-like molecule 8 isoform 1 precursor: "Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1), also referred to as IRC1a." Conserved Domains (3) summary: cd05716 Location: 23  117 Ig_pIgR; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR) and smart00410 Location: 22  105 IG_like; Immunoglobulin like.
Gene ID: 22997 is IGSF9B immunoglobulin superfamily member 9B on 11q25.
- NP_001264214.1 protein turtle homolog B precursor, Conserved Domains (6) summary: cd00096 Location: 41  115 Ig; Immunoglobulin domain, smart00408 Location: 153  210 IGc2; Immunoglobulin C-2 Type, smart00410 Location: 426  505 IG_like; Immunoglobulin like, pfam07679 Location: 139  225 I-set; Immunoglobulin I-set domain and cl11960 Location: 442  505 Ig; Immunoglobulin domain.
Gene ID: 57549 is IGSF9 immunoglobulin superfamily member 9 on 1q23.2.
- NP_001128522.1 protein turtle homolog A isoform a precursor: "Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a)." Conserved Domains (7) summary: cd00096 Location: 154  220 Ig; Immunoglobulin domain, smart00410 Location: 233  319 IG_like; Immunoglobulin like, pfam07679 Location: 136  223 I-set; Immunoglobulin I-set domain, pfam13927 Location: 226  305 Ig_3; Immunoglobulin domain, cl11960 Location: 341  404 Ig; Immunoglobulin domain.
- NP_065840.2 protein turtle homolog A isoform b precursor: "Transcript Variant: This variant (2) uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a." Conserved Domains (7) summary: cd00096 Location: 154  220 Ig; Immunoglobulin domain, smart00410 Location: 233  319 IG_like; Immunoglobulin like, pfam07679 Location: 136  223 I-set; Immunoglobulin I-set domain, pfam13927 Location: 226  305 Ig_3; Immunoglobulin domain and cl11960 Location: 325  388 Ig; Immunoglobulin domain.
Gene ID: 57611 is ISLR2 immunoglobulin superfamily containing leucine rich repeat 2 on 15q24.1.
- NP_001123608.1 immunoglobulin superfamily containing leucine-rich repeat protein 2 precursor: "Transcript Variant: This variant (1) represents the longest transcript. All four transcripts encode the same protein." Conserved Domains (4) summary: cd00096 Location: 256  369 Ig; Immunoglobulin domain.
- NP_001123609.1 immunoglobulin superfamily containing leucine-rich repeat protein 2 precursor: "Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All four transcripts encode the same protein." Conserved Domains (4) summary: cd00096 Location: 256  369 Ig; Immunoglobulin domain.
- NP_001123610.1 immunoglobulin superfamily containing leucine-rich repeat protein 2 precursor: "Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. All four transcripts encode the same protein." Conserved Domains (4) summary: cd00096 Location: 256  369 Ig; Immunoglobulin domain.
- NP_065902.1 immunoglobulin superfamily containing leucine-rich repeat protein 2 precursor: "Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All four transcripts encode the same protein." Conserved Domains (4) summary: cd00096 Location: 256  369 Ig; Immunoglobulin domain.
- XP_016877935.1  immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform X2, Conserved Domains (5) summary: pfam13895 Location: 241  372 Ig_2; Immunoglobulin domain.
Gene ID: 57722 is IGDCC4 immunoglobulin superfamily DCC subclass member 4 on 15q22.31.
- NP_066013.1 immunoglobulin superfamily DCC subclass member 4 precursor, Conserved Domains (6) summary: smart00408 Location: 156  218 IGc2; Immunoglobulin C-2 Type, smart00410 Location: 149  230 IG_like; Immunoglobulin like, pfam07679 Location: 335  422 I-set; Immunoglobulin I-set domain and cl11960 Location: 350  422 Ig; Immunoglobulin domain.
- XP_011520148.1 immunoglobulin superfamily DCC subclass member 4 isoform X3, Conserved Domains (6) summary: smart00408 Location: 156  218 IGc2; Immunoglobulin C-2 Type, smart00410 Location: 149  230 IG_like; Immunoglobulin like, pfam07679 Location: 335  422 I-set; Immunoglobulin I-set domain and cl11960 Location: 350  422 Ig; Immunoglobulin domain.
- XP_011520149.1 immunoglobulin superfamily DCC subclass member 4 isoform X4, Conserved Domains (6) summary: smart00408 Location: 1  55 IGc2; Immunoglobulin C-2 Type, smart00410 Location: 1  69 IG_like; Immunoglobulin like, pfam07679 Location: 73  160 I-set; Immunoglobulin I-set domain and cl11960 Location: 88  160 Ig; Immunoglobulin domain.
- XP_011520147.1 immunoglobulin superfamily DCC subclass member 4 isoform X2, Conserved Domains (6) summary: smart00408 Location: 169  231 IGc2; Immunoglobulin C-2 Type, smart00410 Location: 162  243 IG_like; Immunoglobulin like, pfam07679 Location: 348  435 I-set; Immunoglobulin I-set domain and cl11960 Location: 363  435 Ig; Immunoglobulin domain.
Gene ID: 65978 is IGSF6-DREV1 region containing immunoglobulin superfamily, member 6 and DREV1 on 16.
Gene ID: 83953 is FCAMR Fc fragment of IgA and IgM receptor on 1q32.1.
- NP_001116451.1 high affinity immunoglobulin alpha and immunoglobulin mu Fc receptor isoform a: "Transcript Variant: This variant (2) differs in the 5' UTR and lacks an alternate exon in the 3' coding region resulting in a frameshift, compared to variant 3. The resulting isoform (a) has a shorter and distinct C-terminus, compared to isoform b. Both variants 1 and 2 encode the same isoform." Conserved Domains (2) summary: cd05716 Location: 114  214 Ig_pIgR; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR) and smart00410 Location: 112  215 IG_like; Immunoglobulin like.
- NP_001164102.1 high affinity immunoglobulin alpha and immunoglobulin mu Fc receptor isoform b: "Transcript Variant: This variant (3) represents the longest transcript and encodes the longer isoform (b)." Conserved Domains (2) summary: cd05716 Location: 114  214 Ig_pIgR; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR) and smart00410 Location: 112  215 IG_like; Immunoglobulin like.
- NP_114418.2 high affinity immunoglobulin alpha and immunoglobulin mu Fc receptor isoform a: "Transcript Variant: This variant (1) lacks an alternate exon in the 3' coding region resulting in a frameshift, compared to variant 3. The resulting isoform (a) has a shorter and distinct C-terminus, compared to isoform b. Both variants 1 and 2 encode the same isoform." Conserved Domains (2) summary: cd05716 Location: 114  214 Ig_pIgR; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR) and smart00410 Location: 112  215 IG_like; Immunoglobulin like.
- XP_011508354.1 high affinity immunoglobulin alpha and immunoglobulin mu Fc receptor isoform X2, Conserved Domains (2) summary: cd05716 Location: 102  202 Ig_pIgR; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR) and smart00410 Location: 100  203 IG_like; Immunoglobulin like.
Gene ID: 84966 is IGSF21 immunoglobin superfamily member 21 on 1p36.13: "This gene encodes a protein which has two immunoglobulin (Ig) domains and is a member of the immunoglobulin superfamily. Proteins in this superfamily are usually found on or in cell membranes and act as receptors in immune response pathways."
- NP_116269.3 immunoglobulin superfamily member 21 precursor, Conserved Domains (2) summary: smart00410 Location: 353  430 IG_like; Immunoglobulin like and cl11960 Location: 369  432 Ig; Immunoglobulin domain.
- XP_011540621.1 immunoglobulin superfamily member 21 isoform X4, Conserved Domains (2) summary: smart00410 Location: 156  233 IG_like; Immunoglobulin like and cl11960 Location: 172  235 Ig; Immunoglobulin domain.
- XP_024306212.1 immunoglobulin superfamily member 21 isoform X2, Conserved Domains (1) summary: cl11960 Location: 319  379 Ig; Immunoglobulin domain.
- XP_016858093.1 immunoglobulin superfamily member 21 isoform X1, Conserved Domains (2) summary: smart00410 Location: 347  424 IG_like; Immunoglobulin like and cl11960 Location: 363  426 Ig; Immunoglobulin domain.
- XP_016858094.1 immunoglobulin superfamily member 21 isoform X3, Conserved Domains (2) summary: smart00410 Location: 276  353 IG_like; Immunoglobulin like and cl11960 Location: 292  355Ig; Immunoglobulin domain.
Gene ID: 93185 is IGSF8 immunoglobulin superfamily member 8 on 1q23.2: "This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein."
- NP_001193594.1 immunoglobulin superfamily member 8 precursor: "Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1, 2 and 3 encode the same protein." pfam07686 Location: 28  149 V-set; Immunoglobulin V-set domain and cl11960 Location: 318  419 Ig; Immunoglobulin domain.
- NP_001307176.1 immunoglobulin superfamily member 8 precursor: "Transcript Variant: This variant (3) differs in the 3' UTR, compared to variant 1. Variants 1, 2 and 3 encode the same protein." pfam07686 Location: 28  149 V-set; Immunoglobulin V-set domain and cl11960 Location: 318  419 Ig; Immunoglobulin domain.
- NP_443100.1 immunoglobulin superfamily member 8 precursor: "Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein." pfam07686 Location: 28  149 V-set; Immunoglobulin V-set domain and cl11960 Location: 318  419 Ig; Immunoglobulin domain.
Gene ID: 117166 is WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 on 16p13.3: "This gene encodes a secreted multidomain protein consisting of a signal peptide, a WAP domain, a follistatin domain, an immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. These domains have been implicated frequently in inhibition of various types of proteases, suggesting that the encoded protein may be a multivalent protease inhibitor and may control the action of multiple types of serine proteases as well as metalloproteinases."
- NP_444514.1 WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 precursor, cd05765 Location: 200  280 Ig_3; Subgroup of the immunoglobulin (Ig) superfamily.
Gene ID: 121227 is LRIG3 leucine rich repeats and immunoglobulin like domains 3 on 12q14.1.
- NP_001129523.1 leucine-rich repeats and immunoglobulin-like domains protein 3 isoform 1 precursor: "Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter isoform (1)." cd05763 Location: 560  634 Ig_1; Subgroup of the immunoglobulin (Ig) superfamily, smart00408 Location: 651  714 IGc2; Immunoglobulin C-2 Type, pfam07679 Location: 543  633 I-set; Immunoglobulin I-set domain, and pfam13927 Location: 438  525mIg_3; Immunoglobulin domain.
- NP_700356.2 leucine-rich repeats and immunoglobulin-like domains protein 3 isoform 2 precursor: "Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region and represents the use of an alternate promoter, compared to variant 1, which results in a protein (isoform 2) with a shorter and distinct N-terminus, compared to isoform 1." cd05763 Location: 620  694 Ig_1; Subgroup of the immunoglobulin (Ig) superfamily, smart00408 Location: 711  774 IGc2; Immunoglobulin C-2 Type, pfam07679 Location: 603  693 I-set; Immunoglobulin I-set domain, pfam13927 Location: 498  585 Ig_3; Immunoglobulin domain.
Gene ID: 124857 is WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 on 17q21.33: "The WFIKKN1 protein contains a WAP domain, follistatin domain, immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. This gene encodes a WFIKKN1-related protein which has the same domain organization as the WFIKKN1 protein. The WAP-type, follistatin type, Kunitz-type, and NTR-type protease inhibitory domains may control the action of multiple types of proteases."
- NP_001317270.1 WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 isoform 2, variant 2.
- NP_783165.1  WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 isoform 1 precursor, variant 1, cd05765 Location: 224  304 Ig_3; Subgroup of the immunoglobulin (Ig) superfamily, and pfam07679 Location: 216  304 I-set; Immunoglobulin I-set domain.
Gene ID: 140885 is SIRPA signal regulatory protein alpha on 20p13: "The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene."
- NP_001035111.1 tyrosine-protein phosphatase non-receptor type substrate 1 isoform 1 precursor: "Transcript Variant: This variant (1) uses an alternate, in-frame, splice donor site in the 3' coding region compared to variant 4. This variant encodes a shorter protein (isoform 1) compared to isoform 2. Variants 1, 2, and 3 encode the same protein (isoform 1)." Conserved Domains (4) summary: cd00098 Location: 266  339 IgC; Immunoglobulin Constant domain, smart00410 Location: 41  144 IG_like; Immunoglobulin like, pfam07686 Location: 38  145 V-set; Immunoglobulin V-set domain and cl11960 Location: 143  254 Ig; Immunoglobulin domain.
- NP_001035112.1 tyrosine-protein phosphatase non-receptor type substrate 1 isoform 1 precursor: "Transcript Variant: This variant (2) differs in the 5' UTR and uses an alternate, in-frame, splice donor site in the 3' coding region compared to variant 4. This variant encodes a shorter protein (isoform 1) compared to isoform 2. Variants 1, 2, and 3 encode the same protein (isoform 1)." Conserved Domains (4) summary: cd00098 Location: 266  339 IgC; Immunoglobulin Constant domain, smart00410 Location: 41  144 IG_like; Immunoglobulin like, pfam07686 Location: 38  145 V-set; Immunoglobulin V-set domain and cl11960 Location: 143  254 Ig; Immunoglobulin domain.
- NP_001317657.1 tyrosine-protein phosphatase non-receptor type substrate 1 isoform 2 precursor: "Transcript Variant: This variant (4) encodes the longer protein (isoform 2)." Conserved Domains (3) summary: cd05772 Location: 147  250 IgC_SIRP_domain_2; Signal-regulatory protein (SIRP) immunoglobulin-like domain 2, cd16085 Location: 252  355 IgC_SIRP_domain_3; Signal-regulatory protein (SIRP) immunoglobulin-like domain 3 and cd16097 Location: 35  145 IgV_SIRP; Immunoglobulin (Ig)-like domain of Signal-Regulatory Protein (SIRP).
- NP_542970.1 tyrosine-protein phosphatase non-receptor type substrate 1 isoform 1 precursor: "Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate, in-frame, splice donor site in the 3' coding region compared to variant 4. This variant encodes a shorter protein (isoform 1) compared to isoform 2. Variants 1, 2, and 3 encode the same protein (isoform 1)." Conserved Domains (4) summary: cd00098 Location: 266  339 IgC; Immunoglobulin Constant domain, smart00410 Location: 41  144 IG_like; Immunoglobulin like, pfam07686 Location: 38  145 V-set; Immunoglobulin V-set domain and cl11960 Location: 143  254 Ig; Immunoglobulin domain.
- XP_006723608.1 tyrosine-protein phosphatase non-receptor type substrate 1 isoform X3, Conserved Domains (2) summary: smart00410 Location: 41  144 IG_like; Immunoglobulin like and pfam07686 Location: 38  145 V-set; Immunoglobulin V-set domain.
Gene ID: 146722 is CD300LF CD300 molecule like family member f aka IgSF13 on 17q25.1: "This gene encodes a member of the CD300 protein family. Members of this family are cell surface glycoproteins with a single IgV-like extracellular domain, and are involved in the regulation of immune response. The encoded protein is an inhibitory receptor. Alternative splicing results in multiple transcript variants."
- NP_001276011.1 CMRF35-like molecule 1 isoform 2: "Transcript Variant: This variant (2, also known as sv3) differs in its 5' UTR, uses an alternate start codon, and lacks an exon in the central coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) is shorter and has distinct N- and C-termini, compared to isoform 1." Conserved Domains (2) summary: cd05716 Location: 30  128 Ig_pIgR; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR) and smart00410 Location: 28  128 IG_like; Immunoglobulin like.
- NP_001276012.1 CMRF35-like molecule 1 isoform 3 precursor: "Transcript Variant: This variant (3) includes an alternate exon in the central coding region, which results in a frameshift, compared to variant 1. The encoded isoform (3) has a shorter and distinct C-terminus, compared to isoform 1." Conserved Domains (2) summary: cd05716 Location: 27  125 Ig_pIgR; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR) and smart00410 Location: 25  125 IG_like; Immunoglobulin like.
- NP_001276013.1 CMRF35-like molecule 1 isoform 4: "Transcript Variant: This variant (4) uses an alternate in-frame splice site in the central coding region, compared to variant 1. The encoded isoform (4) is longer, compared to isoform 1." Conserved Domains (3) summary:  cd05716 Location: 27  125 Ig_pIgR; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR) and smart00410 Location: 25  125 IG_like; Immunoglobulin like.
- NP_001276014.1 CMRF35-like molecule 1 isoform 5: "Transcript Variant: This variant (5, also known as sv1) differs in its 5' UTR, and uses an alternate start codon, compared to variant 1. The encoded isoform (5) has a longer and distinct N-terminus, compared to isoform 1." Conserved Domains (3) summary: cd05716 Location: 30  128 Ig_pIgR; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR) and smart00410 Location: 28  128 IG_like; Immunoglobulin like.
- NP_001276015.1 CMRF35-like molecule 1 isoform 6: "Transcript Variant: This variant (6) differs in its 5' UTR, uses an alternate start codon, and lacks an exon in the central coding region, which results in a frameshift, compared to variant 1. The encoded isoform (6) is shorter and has distinct N- and C-termini, compared to isoform 1." Conserved Domains (2) summary: cd05716 Location: 30  128 Ig_pIgR; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR) and smart00410 Location: 28  128 IG_like; Immunoglobulin like.
- NP_001276016.1 CMRF35-like molecule 1 isoform 7 precursor: "Transcript Variant: This variant (7) lacks an exon in the central coding region, which results in a frameshift, compared to variant (1). The encoded isoform (7) has a shorter and distinct C-terminus, compared to variant 1." Conserved Domains (2) summary: cd05716 Location: 27  125 Ig_pIgR; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR) and smart00410 Location: 25  125 IG_like; Immunoglobulin like.
- NP_620587.2  CMRF35-like molecule 1 isoform 1 precursor: "Transcript Variant: This variant (1) encodes isoform 1." Conserved Domains (3) summary: cd05716 Location: 27  125 Ig_pIgR; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR) and smart00410 Location: 25  125 IG_like; Immunoglobulin like.
Gene ID: 147710 is IGSF23 immunoglobulin superfamily member 23 on 19q13.31: "This gene encodes a protein that has one immunoglobulin (Ig) domain and is a member of the immunoglobulin superfamily. Proteins in this superfamily are usually found on or in cell membranes and act as receptors in immune response pathways."
- NP_001192209.1 immunoglobulin superfamily member 23, cl11960 Location: 66  117 Ig; Immunoglobulin domain.
Gene ID: 150084 is IGSF5 immunoglobulin superfamily member 5 on 21q22.2.
- NP_001073913.1 immunoglobulin superfamily member 5, smart00410 Location: 45  138 IG_like; Immunoglobulin like and cl11960 Location: 110  140 Ig; Immunoglobulin domain.
- XP_011527774.1 immunoglobulin superfamily member 5 isoform X1, Conserved Domains (2) summary: smart00410 Location: 135  228 IG_like; Immunoglobulin like and cl11960 Location: 236  307 Ig; Immunoglobulin domain.
Gene ID: 152404 is IGSF11 immunoglobulin superfamily member 11 on 3q13.32: "IGSF11 is an immunoglobulin (Ig) superfamily member that is preferentially expressed in brain and testis. It shares significant homology with coxsackievirus and adenovirus receptor (CXADR; MIM 602621) and endothelial cell-selective adhesion molecule (ESAM)."
- NP_001015887.1 immunoglobulin superfamily member 11 isoform b precursor , Conserved Domains (3) summary: smart00410 Location: 29  124 IG_like; Immunoglobulin like, pfam07686 Location: 27  141 V-set; Immunoglobulin V-set domain and cl11960 Location: 156  223 Ig; Immunoglobulin domain.
- NP_001340247.1 immunoglobulin superfamily member 11 isoform c , Conserved Domains (2) summary: pfam07686 Location: 77  191 V-set; Immunoglobulin V-set domain and pfam13927 Location: 208  269 Ig_3; Immunoglobulin domain.
- NP_001340248.1 immunoglobulin superfamily member 11 isoform d , Conserved Domains (2) summary: pfam07686 Location: 77  191 V-set; Immunoglobulin V-set domain and pfam13927 Location: 208  269 Ig_3; Immunoglobulin domain.
- NP_001340249.1 immunoglobulin superfamily member 11 isoform a precursor , Conserved Domains (2) summary: pfam07686 Location: 26  140 V-set; Immunoglobulin V-set domain and pfam13927 Location:157  218 Ig_3; Immunoglobulin domain.
- NP_001340250.1 immunoglobulin superfamily member 11 isoform e precursor , Conserved Domains (2) summary: pfam07686 Location: 27  141 V-set; Immunoglobulin V-set domain and pfam13927 Location: 158  207 Ig_3; Immunoglobulin domain.
- NP_001340251.1 immunoglobulin superfamily member 11 isoform f precursor , Conserved Domains (2) summary: pfam07686 Location: 26  140 V-set; Immunoglobulin V-set domain and pfam13927 Location: 157  206 Ig_3; Immunoglobulin domain.
- NP_001340252.1 immunoglobulin superfamily member 11 isoform g precursor , Conserved Domains (2) summary: pfam07686 Location: 27  141 V-set; Immunoglobulin V-set domain and pfam13927 Location: 158  219 Ig_3; Immunoglobulin domain.
- NP_001340253.1 immunoglobulin superfamily member 11 isoform h precursor , Conserved Domains (2) summary: pfam07686 Location: 27  141 V-set; Immunoglobulin V-set domain and pfam13927 Location: 158  211 Ig_3; Immunoglobulin domain.
- NP_001340254.1 immunoglobulin superfamily member 11 isoform i , Conserved Domains (2) summary: pfam13927 Location: 99  160 Ig_3; Immunoglobulin domain and cl11960 Location: 8  78 Ig; Immunoglobulin domain.
- NP_001340255.1 immunoglobulin superfamily member 11 isoform j , Conserved Domains (2) summary: pfam13927 Location: 99  148 Ig_3; Immunoglobulin domain and cl11960 Location: 8  78 Ig; Immunoglobulin domain.
- NP_689751.2 immunoglobulin superfamily member 11 isoform a precursor , Conserved Domains (2) summary: pfam07686 Location: 26  140 V-set; Immunoglobulin V-set domain and pfam13927 Location: 157  218 Ig_3; Immunoglobulin domain.
- XP_011510767.1 immunoglobulin superfamily member 11 isoform X1, Conserved Domains (3) summary: smart00410 Location: 78  173 IG_like; Immunoglobulin like, pfam07686 Location: 76  190 V-set; Immunoglobulin V-set domain and cl11960 Location: 205  272 Ig; Immunoglobulin domain.
- XP_011510771.1 immunoglobulin superfamily member 11 isoform X4, Conserved Domains (2) summary: pfam07686 Location: 26  140 V-set; Immunoglobulin V-set domain and pfam13927 Location: 157  218 Ig_3; Immunoglobulin domain.
- XP_011510765.1 immunoglobulin superfamily member 11 isoform X1, Conserved Domains (3) summary: smart00410 Location: 78  173 IG_like; Immunoglobulin like, pfam07686 Location: 76  190 V-set; Immunoglobulin V-set domain and cl11960 Location: 205  272 Ig; Immunoglobulin domain.
- XP_011510766.1 immunoglobulin superfamily member 11 isoform X1, Conserved Domains (3) summary: smart00410 Location: 78  173 IG_like; Immunoglobulin like, pfam07686 Location: 76  190 V-set; Immunoglobulin V-set domain and cl11960 Location: 205  272 Ig; Immunoglobulin domain.
- XP_011510773.1 immunoglobulin superfamily member 11 isoform X5, Conserved Domains (2) summary: smart00410 Location: 79  174 IG_like; Immunoglobulin like and pfam07686 Location: 77  191 V-set; Immunoglobulin V-set domain.
- XP_011510768.1 immunoglobulin superfamily member 11 isoform X2, Conserved Domains (2) summary: smart00410 Location: 79  174 IG_like; Immunoglobulin like and pfam07686 Location: 77  191 V-set; Immunoglobulin V-set domain.
- XP_024309144.1 immunoglobulin superfamily member 11 isoform X3, Conserved Domains (2) summary: pfam07686 Location: 39  153 V-set; Immunoglobulin V-set domain and pfam13927 Location: 170  231 Ig_3; Immunoglobulin domain.
- XP_016861278.1 immunoglobulin superfamily member 11 isoform X6, Conserved Domains (2) summary: pfam13927 Location: 99  160 Ig_3; Immunoglobulin domain and cl11960 Location: 8  78 Ig; Immunoglobulin domain.
- XP_011510776.1 immunoglobulin superfamily member 11 isoform X8, Conserved Domains (3) summary: smart00410 Location: 79  174 IG_like; Immunoglobulin like and pfam07686 Location: 77  191 V-set; Immunoglobulin V-set domain and cl11960 Location: 206  273 Ig; Immunoglobulin domain.
- XP_024309145.1 immunoglobulin superfamily member 11 isoform X7, Conserved Domains (2) summary: pfam07686 Location: 77  191 V-set; Immunoglobulin V-set domain and pfam13927 Location: 208  269 Ig_3; Immunoglobulin domain.
Gene ID: 283284 is IGSF22 immunoglobulin superfamily member 22 on 11p15.1.
- NP_775859.4 immunoglobulin superfamily member 22: "Transcript Variant: This variant (1) represents the protein-coding transcript."
- XP_016873096.1 immunoglobulin superfamily member 22 isoform X1, Conserved Domains (6) summary: cd00096 Location: 456  512 Ig; Immunoglobulin domain, cd05748 Location: 647  717 Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins, smart00410 Location: 637  717 IG_like; Immunoglobulin like, pfam07679 Location: 1233  1322 I-set; Immunoglobulin I-set domain and cl11960 Location: 1256  1322 Ig; Immunoglobulin domain.
- XP_011518333.1 immunoglobulin superfamily member 22 isoform X2, Conserved Domains (6) summary: cd00096 Location: 456  512 Ig; Immunoglobulin domain, cd05748 Location: 647  717 Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins, smart00410 Location: 637  717 IG_like; Immunoglobulin like, pfam07679 Location: 1132  1221 I-set; Immunoglobulin I-set domain and cl11960 Location: 1155  1221 Ig; Immunoglobulin domain.
- XP_011518332.1 immunoglobulin superfamily member 22 isoform X1, Conserved Domains (6) summary: cd00096 Location: 456  512 Ig; Immunoglobulin domain, cd05748 Location: 647  717 Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins, smart00410 Location: 637  717 IG_like; Immunoglobulin like, pfam07679 Location: 1233  1322 I-set; Immunoglobulin I-set domain and cl11960 Location: 1256  1322 Ig; Immunoglobulin domain.
Gene ID: 285313 is IGSF10 immunoglobulin superfamily member 10 on 3q25.1.
- NP_001171616.1 immunoglobulin superfamily member 10 isoform 2: "Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1." smart00408 Location:183  247 IGc2; Immunoglobulin C-2 Type, smart00410 Location:562  649 IG_like; Immunoglobulin like, pfam07679 Location:168  251 I-set; Immunoglobulin I-set domain and cl11960 Location:555  649 Ig; Immunoglobulin domain.
- NP_001171617.1 immunoglobulin superfamily member 10 isoform 3: "Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (3) is shorter at the N-terminus compared to isoform 1." cd00096 Location:527  595 Ig; Immunoglobulin domain, smart00408 Location: 135  199 IGc2; Immunoglobulin C-2 Type, smart00410 Location: 514  601 IG_like; Immunoglobulin like, pfam07679 Location: 120  203 I-set; Immunoglobulin I-set domain and cl11960 Location: 39  115 Ig; Immunoglobulin domain.
- NP_849144.2 immunoglobulin superfamily member 10 isoform 1 precursor: "Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1)." smart00408 Location: 2156  2220 IGc2; Immunoglobulin C-2 Type, smart00409 Location: 2535  2622 IG; Immunoglobulin, smart00410 Location: 582  662 IG_like; Immunoglobulin like, pfam07679, Location: 2141  2224 I-set; Immunoglobulin I-set domain, and cl11960 Location: 1668  1740 Ig; Immunoglobulin domain.
Gene ID: 492311 is IGIP IgA inducing protein on 5q31.3.
- NP_001007190.1 IgA-inducing protein homolog precursor.

# Hypotheses
- Downstream core promoters may work as transcription factors even as their complements or inverses.
- In addition to the DNA binding sequences listed above, the transcription factors that can open up and attach through the local epigenome need to be known and specified.