Pathophysiology template

# Introduction to the Pathophysiology Page
- The page name should be "(Disease name) pathophysiology", with only the first letter of the title capitalized.
- Goal: to explain the biological mechanisms underlying the disease state. To provide a description of the pathophysiology at a cellular and molecular level, the pathophysiology at a gross and functional level, and the causative factor in the disease process. The page can also include a description of the genetic abnormalities, embryological and developmental abnormalities, pathogenesis, and pathology images.
- As with all microchapter pages linking to the main page, at the top of the edit box put {{CMG}}, your name template, and the microchapter navigation template you created at the beginning.
- Remember to follow the same format and capitalization of letters  as outlined in the template below.
- You should include the name of the disease in the first sentence of every subsection.
- Remember to create links within Wikidoc by placing ] around key words which you want to link to other pages. Make sure you make your links as specific as possible. For example if a sentence contained the phrase anterior spinal artery syndrome, the link should be to anterior spinal artery syndrome not anterior or artery or syndrome.  For more information on how to create links click here.
Template to write pathophysiology microchapter

# Overview
- The overview section should include the disease name in the first sentence.
- The goal is to summarize the pathophysiology page in several sentences. This section can be the same as the pathophysiology segment on the overview page.
- To see an example of an overview section on a symptoms page, click here.

## Template
- The overview is highly dependent on the individual disease pathophysiology. There is no specific template preference for the first sentence.
Template Sentences:
Examples:

# Pathogenesis
Pathogenesis is the mechanism by which a certain factor causes disease (pathos = disease, genesis = development). The term can also be used to describe the development of the disease, whether it is acute, chronic, or recurrent. It can also be used to describe whether the disease causes inflammation, malignancy, necrosis etc.

### Template Sentences
IF the pathogenesis of the disease is unclear:
- The exact pathogenesis of  is not fully understood.
- It is thought that  is the result of / is mediated by / is produced by / is caused by either , , or .
IF the disease is infectious...
- ...and the route of transmission is known:
 is usually transmitted via the  route to the human host.
Following transmission/ingestion, the  uses the  to invade the  cell.
-  is usually transmitted via the  route to the human host.
- Following transmission/ingestion, the  uses the  to invade the  cell.
IF the disease has a known genetic component:
-  is transmitted in  pattern.
- Genes involved in the pathogenesis of  include , , and .
IF certain pathology findings are characteristic of the disease:
- On gross pathology, , , and  are characteristic findings of .
- On microscopic histopathological analysis, , , and  are characteristic findings of .
Other relevant information may include the action of the pathogen on a molecular level, the bodys response, whether or not mutations play a role in the disease development, whether the pathophysiology of the disease is different among subgroups of the disease, etc. Additional template sentences are listed below. Due to the highly variable nature of pathophysiology among various diseases, this list is not comprehensive.
-  arises from s, which are  cells that are normally involved in .
- The development of  is the result of multiple genetic mutations.
- The progression to  usually involves the .
- The pathophysiology of  depends on the histological subtype.
- For an example of a pathogenesis section within a pathophysiology page, click here

# Genetics
- Some diseases are genetic, and have particular inheritance patterns, and express different phenotypes.
- The effect that genetics may have on the pathophysiology of a disease can be described in this section.

### Template sentences
-  is transmitted in  pattern.
- Genes involved in the pathogenesis of  include , , and .

# Associated Conditions
- Conditions associated with the disease can be detailed in this section.

### Template sentences
- The most important conditions/diseases associated with  include:
Condition 1: A brief explanation of the condition and its association with the disease
Condition 2: A brief explanation of the condition and its association with the disease
- Condition 1: A brief explanation of the condition and its association with the disease
- Condition 2: A brief explanation of the condition and its association with the disease
For an example of an associated conditions sub-section of pathophysiology, click here.

# Gross Pathology
- Gross pathology refers to macroscopic or larger scale manifestations of disease in organs, tissues and body cavities. The term is commonly used by pathologist to refer to diagnostically useful findings made during the gross examination portion of surgical specimen processing or an autopsy.
- Template Sentences 1: On gross pathology, , , and  are characteristic findings of .
- Template Sentence 2: The most important characteristics of  on gross pathology are:
Organ 1: List of characteristics + image
Organ 2: List of characteristics + image
Organ 3: List of characteristics + image
- Organ 1: List of characteristics + image
- Organ 2: List of characteristics + image
- Organ 3: List of characteristics + image
- This section is a good place to include pictures. Search for copyleft images on The Pathology Wiki  and Ask Dr. Wiki .
- For an example of this section, click here.

# Microscopic Pathology
- Microscopic pathology is the disease process as it occurs at the microscopic level.
- Template Sentence 1: On microscopic histopathological analysis, , , and  are characteristic findings of .
- Template Sentence 2: The most important histopathological characteristics of  are summarized in the table below:
- This section is a good place to include pictures. Search for copyleft images on The Pathology Wiki  and Ask Dr. Wiki .
- For an example of this section, click here.