GLM box gene transcriptions
"The primary structure of hordein  polypeptides is closely related to that of prolamins from other grass species from the Pooideae subfamily, such as wheat and rye (Shewry & Tatham 1990;Shewry et al. 1995). The close evolutionary relationship is also manifested by the conservation of a putative regulatory element in their gene promoters, the endosperm box (Forde et al. 1985;Kreis et al. 1985). This conserved region consists of two motifs, a 7 bp element (5TGTAAAG3) termed the Prolamin Box (P-box) or endosperm motif (EM) followed at a distance of up to 8 nucleotides by the GCN4-like motif (GLM) which has the 5(G/A)TGA(G/C)TCA(T/C)3 consensus sequence (reviewed by Muller et al. 1995)."

# GLM consensus sequences
The "GCN4-like motif (GLM)  has the 5(G/A)TGA(G/C)TCA(T/C)3 consensus sequence (reviewed by Muller et al. 1995)."

# Hypotheses
- A1BG has no GLM boxes in either promoter.
- A1BG is not transcribed by a GLM box.
- A GLM box does not participate in the transcription of A1BG.

# GLM box sampling of A1BG promoters
For the Basic programs (starting with SuccessablesGLM.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), including extending the number of nts from 958 to 4445, the programs are, are looking for, and found:
- negative strand in the negative direction (from ZSCAN22 to A1BG) is SuccessablesGLM--.bas, looking for 3'-(G/A)TGA(G/C)TCA(T/C)-5', 0,
- negative strand in the positive direction (from ZNF497 to A1BG) is SuccessablesGLM-+.bas, looking for 3'-(G/A)TGA(G/C)TCA(T/C)-5', 0,
- positive strand in the negative direction is SuccessablesGLM+-.bas, looking for 3'-(G/A)TGA(G/C)TCA(T/C)-5', 0,
- positive strand in the positive direction is SuccessablesGLM++.bas, looking for 3'-(G/A)TGA(G/C)TCA(T/C)-5', 0,
- complement, negative strand, negative direction is SuccessablesGLMc--.bas, looking for 3'-(C/T)ACT(G/C)AGT(A/G)-5', 0,
- complement, negative strand, positive direction is SuccessablesGLMc-+.bas, looking for 3'-(C/T)ACT(G/C)AGT(A/G)-5', 0,
- complement, positive strand, negative direction is SuccessablesGLMc+-.bas, looking for 3'-(C/T)ACT(G/C)AGT(A/G)-5', 0,
- complement, positive strand, positive direction is SuccessablesGLMc++.bas, looking for 3'-(C/T)ACT(G/C)AGT(A/G)-5', 0,
- inverse complement, negative strand, negative direction is SuccessablesGLMci--.bas, looking for 3'-(A/G)TGA(G/C)TCA(C/T)-5', 0,
- inverse complement, negative strand, positive direction is SuccessablesGLMci-+.bas, looking for 3'-(A/G)TGA(G/C)TCA(C/T)-5', 0,
- inverse complement, positive strand, negative direction is SuccessablesGLMci+-.bas, looking for 3'-(A/G)TGA(G/C)TCA(C/T)-5', 0,
- inverse complement, positive strand, positive direction is SuccessablesGLMci++.bas, looking for 3'-(A/G)TGA(G/C)TCA(C/T)-5', 0,
- inverse, negative strand, negative direction, is SuccessablesGLMi--.bas, looking for 3'-(T/C)ACT(G/C)AGT(G/A)-5', 0,
- inverse, negative strand, positive direction, is SuccessablesGLMi-+.bas, looking for 3'-(T/C)ACT(G/C)AGT(G/A)-5', 0,
- inverse, positive strand, negative direction, is SuccessablesGLMi+-.bas, looking for 3'-(T/C)ACT(G/C)AGT(G/A)-5', 0,
- inverse, positive strand, positive direction, is SuccessablesGLMi++.bas, looking for 3'-(T/C)ACT(G/C)AGT(G/A)-5', 0.

# GCN4 motifs
Most bZIP proteins show high binding affinity for the ACGT motifs, which include  a GCN4 motif, namely TGA(G/C)TCA.

# Human genes

# Interactions

# GCN4 consensus sequences
The GCN4 motif consensus sequence is TGA(G/C)TCA.
For the Basic programs testing consensus sequence TGA(G/C)TCA (starting with SuccessablesGCN4.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found:
- Negative strand, negative direction, looking for TGA(C/G/T)T(A/C/G)(A/T), 2, TGAGTCT at 3644, TGACTAT at 3544.
- Positive strand, negative direction, looking for TGA(C/G/T)T(A/C/G)(A/T), 3, TGAGTAT at 3829, TGACTCT at 2788, TGAGTCT at 278.
- Negative strand, positive direction, looking for TGA(C/G/T)T(A/C/G)(A/T), 5, TGATTAT at 4165, TGATTAT at 4158, TGAGTGA at 3712, TGAGTGT at 3592, TGATTGT at 2678.
- Positive strand, positive direction, looking for TGA(C/G/T)T(A/C/G)(A/T), 2, TGAGTGA at 4338, TGACTAA at 2676.
Inverse complement is the same as the direct. A conserved AP-1 (TGAGTCA) site does not occur in either side of A1BG.

# Samplings
Copying an apparent consensus sequence of TGACTCA, TGAGTCA and putting it in "F" finds none located between ZSCAN22 and A1BG and none between ZNF497 and A1BG as can be found by the computer programs.

# Acknowledgements
The content on this page was first contributed by: Henry A. Hoff.
Initial content for this page in some instances came from Wikiversity.