List of ICD-9 codes 240-279: Endocrine, nutritional and metabolic diseases, and immunity disorders

# 3. Endocrine, nutritional and metabolic diseases, and immunity disorders (240-279)

## disorders of thyroid gland (240-246)
- (240) Simple and unspecified goiter
(240.9) Goiter, unspec.
- (240.9) Goiter, unspec.
- (241) Nontoxic nodular goiter
(241.0) Thyroid nodule
(241.9) Goiter, unspec. nontoxic nodular
- (241.0) Thyroid nodule
- (241.9) Goiter, unspec. nontoxic nodular
- (242) Thyrotoxicosis with or without goiter
(242.0) Goiter toxic, diffuse
(242.9) Hyperthyroidism, NOS
- (242.0) Goiter toxic, diffuse
- (242.9) Hyperthyroidism, NOS
- (243) Congenital hypothyroidism
- (244) Acquired hypothyroidism
(244.0) Hypothyroidism, post-surgical
(244.1) Hypothyroidism, post-ablative
(244.9) Hypothyroidism, unspec.
- (244.0) Hypothyroidism, post-surgical
- (244.1) Hypothyroidism, post-ablative
- (244.9) Hypothyroidism, unspec.
- (245) Thyroiditis
(245.0) Thyroiditis, acute
(245.1) Thyroiditis, subacute
(245.2) Thyroiditis, chronic, Hashimoto's
- (245.0) Thyroiditis, acute
- (245.1) Thyroiditis, subacute
- (245.2) Thyroiditis, chronic, Hashimoto's
- (246) Other disorders of thyroid
(246.2) Thyroid cyst
- (246.2) Thyroid cyst

## diseases of other endocrine glands (250-259)
- Note: for 250-259, the following fifth digit can be added:
(250.x0) Diabetes mellitus type 2
(250.x1) Diabetes mellitus type 1
(250.x2) Diabetes mellitus type 2, uncontrolled
(250.x3) Diabetes mellitus type 1, uncontrolled
- (250.x0) Diabetes mellitus type 2
- (250.x1) Diabetes mellitus type 1
- (250.x2) Diabetes mellitus type 2, uncontrolled
- (250.x3) Diabetes mellitus type 1, uncontrolled
- (250) Diabetes mellitus
(250.0) Diabetes mellitus without mention of complication
(250.1) Diabetes with ketoacidosis
(250.2) Diabetes with hyperosmolarity
(250.3) Diabetes with other coma
(250.4) Diabetes with renal manifestations
(250.5) Diabetes with ophthalmic manifestations
(250.6) Diabetes with neurological manifestations
(250.7) Diabetes with peripheral circulatory disorders
(250.8) Diabetes with other specified manifestations
(250.9) Diabetes with unspecified complication
- (250.0) Diabetes mellitus without mention of complication
- (250.1) Diabetes with ketoacidosis
- (250.2) Diabetes with hyperosmolarity
- (250.3) Diabetes with other coma
- (250.4) Diabetes with renal manifestations
- (250.5) Diabetes with ophthalmic manifestations
- (250.6) Diabetes with neurological manifestations
- (250.7) Diabetes with peripheral circulatory disorders
- (250.8) Diabetes with other specified manifestations
- (250.9) Diabetes with unspecified complication
- (251) Other disorders of pancreatic internal secretion
(251.2) Hypoglycemia, nondiabetic, unspec.
- (251.2) Hypoglycemia, nondiabetic, unspec.
- (252) Disorders of parathyroid gland
(252.0) Hyperparathyroidism, unspec.
(252.01) Hyperparathyroidism, primary
(252.1) Hypoparathyroidism
- (252.0) Hyperparathyroidism, unspec.
(252.01) Hyperparathyroidism, primary
- (252.01) Hyperparathyroidism, primary
- (252.1) Hypoparathyroidism
- (253) Disorders of the pituitary gland and its hypothalamic control
(253.3) Growth hormone deficiency
(253.6) SIADH
- (253.3) Growth hormone deficiency
- (253.6) SIADH
- (254) Diseases of thymus gland
- (255) Disorders of adrenal glands
(255.0) Cushing's syndrome
- (255.0) Cushing's syndrome
- (256) Ovarian dysfunction
(256.2) Ovarian failure, postablative
(256.39) Ovarian failure, other
(256.4) Ovaries, polycystic
- (256.2) Ovarian failure, postablative
(256.39) Ovarian failure, other
- (256.39) Ovarian failure, other
- (256.4) Ovaries, polycystic
- (257) Testicular dysfunction
(257.2) Testicular hypofunction
- (257.2) Testicular hypofunction
- (258) Polyglandular dysfunction and related disorders
- (259) Other endocrine disorders
(259.0) Puberty, delayed
(259.1) Sexual precocity
- (259.0) Puberty, delayed
- (259.1) Sexual precocity

## nutritional deficiencies (260-269)
- (260) Kwashiorkor
- (261) Nutritional marasmus
- (262) Other severe protein-calorie malnutrition
- (263) Other and unspecified protein-calorie malnutrition
- (264) Vitamin A deficiency
(264.0) With conjunctival xerosis
(264.1) With conjunctival xerosis and Bitot's spot
(264.2) With corneal xerosis
(264.3) With corneal ulceration and xerosis
(264.4) With keratomalacia
(264.5) With night blindness
(264.6) With xerophthalmic scars of cornea
(264.7) Other ocular manifestations of vitamin A deficiency
(264.8) Other manifestations of vitamin A deficiency
(264.9) Unspecified vitamin A deficiency
- (264.0) With conjunctival xerosis
- (264.1) With conjunctival xerosis and Bitot's spot
- (264.2) With corneal xerosis
- (264.3) With corneal ulceration and xerosis
- (264.4) With keratomalacia
- (264.5) With night blindness
- (264.6) With xerophthalmic scars of cornea
- (264.7) Other ocular manifestations of vitamin A deficiency
- (264.8) Other manifestations of vitamin A deficiency
- (264.9) Unspecified vitamin A deficiency
- (265) Thiamine and niacin deficiency states
(265.0) Beriberi
(265.1) Other and unspecified manifestations of thiamine deficiency
Wernicke's encephalopathy
(265.2) Pellagra
- (265.0) Beriberi
- (265.1) Other and unspecified manifestations of thiamine deficiency
Wernicke's encephalopathy
- Wernicke's encephalopathy
- (265.2) Pellagra
- (266) Deficiency of B-complex components
(266.0) Ariboflavinosis
(266.2) B12 deficiency w/o anemia
- (266.0) Ariboflavinosis
- (266.2) B12 deficiency w/o anemia
- (267) Ascorbic acid deficiency
- (268) Vitamin D deficiency
- (269) Other nutritional deficiencies
(269.0) Deficiency of vitamin K
(269.1) Deficiency of other vitamins
(269.2) Unspecified vitamin deficiency
(269.3) Mineral deficiency, not elsewhere classified
- (269.0) Deficiency of vitamin K
- (269.1) Deficiency of other vitamins
- (269.2) Unspecified vitamin deficiency
- (269.3) Mineral deficiency, not elsewhere classified

## other metabolic and immunity disorders (270-279)
- (270) Disorders of amino-acid transport and metabolism
(270.0) Disturbances of amino-acid transport
Cystinosis
Cystinuria
Hartnup disease
(270.1) Phenylketonuria (PKU)
(270.2) Other disturbances of aromatic amino-acid metabolism
Albinism
Alkaptonuria
Hypertyrosinemia
Ochronosis
Waardenburg syndrome
(270.3) Disturbances of branched-chain amino-acid metabolism
Maple syrup urine disease
(270.4) Disturbances of sulphur-bearing amino-acid metabolism
Homocystinuria
(270.6) Disorders of urea cycle metabolism
Citrullinemia
Hyperammonemia
(270.8) Other specified disorders of amino-acid metabolism
Trimethylaminuria
- (270.0) Disturbances of amino-acid transport
Cystinosis
Cystinuria
Hartnup disease
- Cystinosis
- Cystinuria
- Hartnup disease
- (270.1) Phenylketonuria (PKU)
- (270.2) Other disturbances of aromatic amino-acid metabolism
Albinism
Alkaptonuria
Hypertyrosinemia
Ochronosis
Waardenburg syndrome
- Albinism
- Alkaptonuria
- Hypertyrosinemia
- Ochronosis
- Waardenburg syndrome
- (270.3) Disturbances of branched-chain amino-acid metabolism
Maple syrup urine disease
- Maple syrup urine disease
- (270.4) Disturbances of sulphur-bearing amino-acid metabolism
Homocystinuria
- Homocystinuria
- (270.6) Disorders of urea cycle metabolism
Citrullinemia
Hyperammonemia
- Citrullinemia
- Hyperammonemia
- (270.8) Other specified disorders of amino-acid metabolism
Trimethylaminuria
- Trimethylaminuria
- (271) Disorders of carbohydrate transport and metabolism
(271.0) Glycogenosis
von Gierke's disease
McArdle's disease
Pompe's disease
(271.1) Galactosemia
(271.2) Hereditary fructose intolerance
(271.3) Intestinal disaccharidase deficiencies and disaccharide malabsorption
Lactose intolerance
Glucose intolerance
(271.4) Renal glycosuria
- (271.0) Glycogenosis
von Gierke's disease
McArdle's disease
Pompe's disease
- von Gierke's disease
- McArdle's disease
- Pompe's disease
- (271.1) Galactosemia
- (271.2) Hereditary fructose intolerance
- (271.3) Intestinal disaccharidase deficiencies and disaccharide malabsorption
Lactose intolerance
Glucose intolerance
- Lactose intolerance
- Glucose intolerance
- (271.4) Renal glycosuria
- (272) Disorders of lipoid metabolism
(272.0) Pure hypercholesterolemia
Fredrickson Type IIa hyperlipoproteinemia
Familial hypercholesterolemia
(272.1) Pure hyperglyceridemia
Hypertriglyceridemia, essential
Fredrickson Type IV hyperlipoproteinemia
(272.2) Hyperlipidemia, mixed
Fredrickson Type IIb or III hyperlipoproteinemia
Tubo-eruptive xanthoma
Xanthoma tuberosum
(272.3) Hyperchylomicronemia
Burger-Grutz syndrome
Fredrickson type I or V hyperlipoproteinemia
Hyperlipidemia, Group D
Mixed hyperglyceridemia
(272.4) Other and unspecified hyperlipidemia
Alpha-lipoproteinemia
Combined hyperlipidemia
(272.5) Lipoprotein deficiencies
Abetalipoproteinemia
Bassen-Kornzweig syndrome
High-density lipoid deficiency
Hypoalphalipoproteinemia
Hypobetalipoproteinemia (familial)
(272.6) Lipodystrophy
(272.7) Lipidoses
Gaucher's disease
Niemann-Pick disease
Sea-blue histiocyte syndrome
(272.8) Other disorders of lipoid metabolism
Carnitine-acylcarnitine translocase deficiency
Mitochondrial trifunctional protein deficiency
- (272.0) Pure hypercholesterolemia
Fredrickson Type IIa hyperlipoproteinemia
Familial hypercholesterolemia
- Fredrickson Type IIa hyperlipoproteinemia
- Familial hypercholesterolemia
- (272.1) Pure hyperglyceridemia
Hypertriglyceridemia, essential
Fredrickson Type IV hyperlipoproteinemia
- Hypertriglyceridemia, essential
- Fredrickson Type IV hyperlipoproteinemia
- (272.2) Hyperlipidemia, mixed
Fredrickson Type IIb or III hyperlipoproteinemia
Tubo-eruptive xanthoma
Xanthoma tuberosum
- Fredrickson Type IIb or III hyperlipoproteinemia
- Tubo-eruptive xanthoma
- Xanthoma tuberosum
- (272.3) Hyperchylomicronemia
Burger-Grutz syndrome
Fredrickson type I or V hyperlipoproteinemia
Hyperlipidemia, Group D
Mixed hyperglyceridemia
- Burger-Grutz syndrome
- Fredrickson type I or V hyperlipoproteinemia
- Hyperlipidemia, Group D
- Mixed hyperglyceridemia
- (272.4) Other and unspecified hyperlipidemia
Alpha-lipoproteinemia
Combined hyperlipidemia
- Alpha-lipoproteinemia
- Combined hyperlipidemia
- (272.5) Lipoprotein deficiencies
Abetalipoproteinemia
Bassen-Kornzweig syndrome
High-density lipoid deficiency
Hypoalphalipoproteinemia
Hypobetalipoproteinemia (familial)
- Abetalipoproteinemia
- Bassen-Kornzweig syndrome
- High-density lipoid deficiency
- Hypoalphalipoproteinemia
- Hypobetalipoproteinemia (familial)
- (272.6) Lipodystrophy
- (272.7) Lipidoses
Gaucher's disease
Niemann-Pick disease
Sea-blue histiocyte syndrome
- Gaucher's disease
- Niemann-Pick disease
- Sea-blue histiocyte syndrome
- (272.8) Other disorders of lipoid metabolism
Carnitine-acylcarnitine translocase deficiency
Mitochondrial trifunctional protein deficiency
- Carnitine-acylcarnitine translocase deficiency
- Mitochondrial trifunctional protein deficiency
- (273) Disorders of plasma protein metabolism
(273.0) Polyclonal hypergammaglobulinemia
(273.1) Monoclonal paraproteinemia
(273.2) Other paraproteinemias
(273.3) Macroglobulinemia
Waldenstrom macroglobulinemia
(273.8) Other disorders of plasma protein metabolism
- (273.0) Polyclonal hypergammaglobulinemia
- (273.1) Monoclonal paraproteinemia
- (273.2) Other paraproteinemias
- (273.3) Macroglobulinemia
Waldenstrom macroglobulinemia
- Waldenstrom macroglobulinemia
- (273.8) Other disorders of plasma protein metabolism
- (274) Gout
(274.0) Gouty arthropathy
- (274.0) Gouty arthropathy
- (275) Disorders of mineral metabolism
(275.0) Disorders of iron metabolism
Hemochromatosis
(275.1) Disorders of copper metabolism
Wilson's disease
(275.2) Disorders of magnesium metabolism
Hypermagnesemia
Hypomagnesemia
(275.3) Disorders of phosphorus metabolism
Familial hypophosphatemia
Hypophosphatasia
(275.4) Disorders of calcium metabolism
(275.41) Hypocalcemia
(275.42) Hypercalcemia
(275.49) Pseudohypoparathyroidism
- (275.0) Disorders of iron metabolism
Hemochromatosis
- Hemochromatosis
- (275.1) Disorders of copper metabolism
Wilson's disease
- Wilson's disease
- (275.2) Disorders of magnesium metabolism
Hypermagnesemia
Hypomagnesemia
- Hypermagnesemia
- Hypomagnesemia
- (275.3) Disorders of phosphorus metabolism
Familial hypophosphatemia
Hypophosphatasia
- Familial hypophosphatemia
- Hypophosphatasia
- (275.4) Disorders of calcium metabolism
(275.41) Hypocalcemia
(275.42) Hypercalcemia
(275.49) Pseudohypoparathyroidism
- (275.41) Hypocalcemia
- (275.42) Hypercalcemia
- (275.49) Pseudohypoparathyroidism
- (276) Disorders of fluid, electrolyte, and acid-base balance
(276.0) Hypernatremia
(276.1) Hyponatremia
(276.2) Acidosis
(276.3) Alkalosis
(276.4) Mixed acid-base balance disorder
(276.5) Dehydration
(276.52) Hypovolemia
(276.7) Hyperkalemia
(276.8) Hypokalemia
- (276.0) Hypernatremia
- (276.1) Hyponatremia
- (276.2) Acidosis
- (276.3) Alkalosis
- (276.4) Mixed acid-base balance disorder
- (276.5) Dehydration
(276.52) Hypovolemia
- (276.52) Hypovolemia
- (276.7) Hyperkalemia
- (276.8) Hypokalemia
- (277) Other and unspecified disorders of metabolism
(277.0) Cystic fibrosis
(277.1) Disorders of porphyrin metabolism
Porphyria
Acute intermittent porphyria
(277.2) Other disorders of purine and pyrimidine metabolism
Lesch-Nyhan syndrome
Xanthinuria
(277.3) Amyloidosis
Familial Mediterranean fever
(277.4) Hyperbilirubinemia
Crigler-Najjar syndrome
Gilbert's syndrome
(277.5) Mucopolysaccharidosis
Hunter's syndrome
Hurler's syndrome
Morquio-Brailsford disease
Sanfilippo's syndrome
(277.6) Other deficiencies of circulating enzymes
Alpha 1-antitrypsin deficiency
Hereditary angioedema
(277.7) Dysmetabolic syndrome x
Metabolic syndrome
(277.8) Other specified disorders of metabolism
(277.81) Primary carnitine deficiency
(277.82) Carnitine deficiency due to inborn errors of metabolism
(277.83) Iatrogenic carnitine deficiency
(277.84) Other secondary carnitine deficiency
(277.85) Disorders of fatty acid oxidation metabolism
Carnitine palmitoyltransferase I deficiency
Carnitine palmitoyltransferase II deficiency
Very long-chain acyl-coenzyme A dehydrogenase deficiency
Long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency
Medium-chain acyl-coenzyme A dehydrogenase deficiency
(277.86) Disorders of peroxisomal metabolism
Zellweger syndrome
(277.87) Disorders of mitochondrial metabolism
Kearns-Sayre syndrome
Mitochondrial encephalopathy, lactic acidosis and stroke-like episodes (MELAS syndrome)
Mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE)
Myoclonus with epilepsy and with ragged red fibers (MERRF syndrome)
Neuropathy, ataxia and retinitis pigmentosa (NARP syndrome)
(277.89) Other specified disorders of metabolism
- (277.0) Cystic fibrosis
- (277.1) Disorders of porphyrin metabolism
Porphyria
Acute intermittent porphyria
- Porphyria
Acute intermittent porphyria
- Acute intermittent porphyria
- (277.2) Other disorders of purine and pyrimidine metabolism
Lesch-Nyhan syndrome
Xanthinuria
- Lesch-Nyhan syndrome
- Xanthinuria
- (277.3) Amyloidosis
Familial Mediterranean fever
- Familial Mediterranean fever
- (277.4) Hyperbilirubinemia
Crigler-Najjar syndrome
Gilbert's syndrome
- Crigler-Najjar syndrome
- Gilbert's syndrome
- (277.5) Mucopolysaccharidosis
Hunter's syndrome
Hurler's syndrome
Morquio-Brailsford disease
Sanfilippo's syndrome
- Hunter's syndrome
- Hurler's syndrome
- Morquio-Brailsford disease
- Sanfilippo's syndrome
- (277.6) Other deficiencies of circulating enzymes
Alpha 1-antitrypsin deficiency
Hereditary angioedema
- Alpha 1-antitrypsin deficiency
- Hereditary angioedema
- (277.7) Dysmetabolic syndrome x
Metabolic syndrome
- Metabolic syndrome
- (277.8) Other specified disorders of metabolism
(277.81) Primary carnitine deficiency
(277.82) Carnitine deficiency due to inborn errors of metabolism
(277.83) Iatrogenic carnitine deficiency
(277.84) Other secondary carnitine deficiency
(277.85) Disorders of fatty acid oxidation metabolism
Carnitine palmitoyltransferase I deficiency
Carnitine palmitoyltransferase II deficiency
Very long-chain acyl-coenzyme A dehydrogenase deficiency
Long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency
Medium-chain acyl-coenzyme A dehydrogenase deficiency
(277.86) Disorders of peroxisomal metabolism
Zellweger syndrome
(277.87) Disorders of mitochondrial metabolism
Kearns-Sayre syndrome
Mitochondrial encephalopathy, lactic acidosis and stroke-like episodes (MELAS syndrome)
Mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE)
Myoclonus with epilepsy and with ragged red fibers (MERRF syndrome)
Neuropathy, ataxia and retinitis pigmentosa (NARP syndrome)
(277.89) Other specified disorders of metabolism
- (277.81) Primary carnitine deficiency
- (277.82) Carnitine deficiency due to inborn errors of metabolism
- (277.83) Iatrogenic carnitine deficiency
- (277.84) Other secondary carnitine deficiency
- (277.85) Disorders of fatty acid oxidation metabolism
Carnitine palmitoyltransferase I deficiency
Carnitine palmitoyltransferase II deficiency
Very long-chain acyl-coenzyme A dehydrogenase deficiency
Long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency
Medium-chain acyl-coenzyme A dehydrogenase deficiency
- Carnitine palmitoyltransferase I deficiency
- Carnitine palmitoyltransferase II deficiency
- Very long-chain acyl-coenzyme A dehydrogenase deficiency
- Long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency
- Medium-chain acyl-coenzyme A dehydrogenase deficiency
- (277.86) Disorders of peroxisomal metabolism
Zellweger syndrome
- Zellweger syndrome
- (277.87) Disorders of mitochondrial metabolism
Kearns-Sayre syndrome
Mitochondrial encephalopathy, lactic acidosis and stroke-like episodes (MELAS syndrome)
Mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE)
Myoclonus with epilepsy and with ragged red fibers (MERRF syndrome)
Neuropathy, ataxia and retinitis pigmentosa (NARP syndrome)
- Kearns-Sayre syndrome
- Mitochondrial encephalopathy, lactic acidosis and stroke-like episodes (MELAS syndrome)
- Mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE)
- Myoclonus with epilepsy and with ragged red fibers (MERRF syndrome)
- Neuropathy, ataxia and retinitis pigmentosa (NARP syndrome)
- (277.89) Other specified disorders of metabolism
- (278) Obesity and other hyperalimentation
(278.0) Obesity, NOS
(278.1) Localized adiposity
(278.2) Hypervitaminosis A
(278.3) Hypercarotinemia
(278.4) Hypervitaminosis D
- (278.0) Obesity, NOS
- (278.1) Localized adiposity
- (278.2) Hypervitaminosis A
- (278.3) Hypercarotinemia
- (278.4) Hypervitaminosis D
- (279) Disorders involving the immune mechanism
(279.0) Deficiency of humoral immunity
(279.1) Deficiency of cell-mediated immunity
(279.11) DiGeorge syndrome
(279.12) Wiskott-Aldrich syndrome
(279.2) Combined immunity deficiency
Severe combined immunodeficiency
- (279.0) Deficiency of humoral immunity
- (279.1) Deficiency of cell-mediated immunity
(279.11) DiGeorge syndrome
(279.12) Wiskott-Aldrich syndrome
- (279.11) DiGeorge syndrome
- (279.12) Wiskott-Aldrich syndrome
- (279.2) Combined immunity deficiency
Severe combined immunodeficiency
- Severe combined immunodeficiency