Sodium hypochlorite

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# Overview
Sodium hypochlorite is an anti- infective agent that is FDA approved for the treatment of infection of the skin and tissue.   Common adverse reactions include .

# Adult Indications and Dosage

## FDA-Labeled Indications and Dosage (Adult)
- To prevent and treat infection of the skin and tissue.
- Pre and post surgery- Cuts, abrasions and skin ulcers
- Dosing Information
- Pour on or apply to affected area. For wound management, use as an irrigant, cleanser, or the wetting agent for a wet-to-moist dressing. Apply once daily for lightly to moderately exudative wounds. Apply twice daily for highly exudative or highly contaminated wounds. Protect surrounding intact skin with a moisture barrier ointment or skin sealant as needed.

## Off-Label Use and Dosage (Adult)

### Guideline-Supported Use
- There is limited information regarding Off-Label Guideline-Supported Use of Sodium hypochlorite in adult patients.

### NonGuideline-Supported Use
- There is limited information regarding Off-Label NonGuideline-Supported Use of Sodium hypochlorite in adult patients.

# Pediatric Indications and Dosage

## FDA-Labeled Indications and Dosage (Pediatric)
There is limited information regarding Sodium hypochlorite FDA-Labeled Indications and Dosage (Pediatric) in the drug label.

## Off-Label Use and Dosage (Pediatric)

### Guideline-Supported Use
- There is limited information regarding Off-Label Guideline-Supported Use of Sodium hypochlorite in pediatric patients.

### NonGuideline-Supported Use
- There is limited information regarding Off-Label NonGuideline-Supported Use of Sodium hypochlorite in pediatric patients.

# Contraindications
There is limited information regarding Sodium hypochlorite Contraindications in the drug label.

# Warnings
- For external use only.
- Stop use and ask a doctor if  redness, irritation, swelling or pain persists or increases.
- Do not use if sensitive to chlorine compounds.
- Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

# Adverse Reactions

## Clinical Trials Experience
There is limited information regarding Sodium hypochlorite Clinical Trials Experience in the drug label.

## Postmarketing Experience
There is limited information regarding Sodium hypochlorite Postmarketing Experience in the drug label.

# Drug Interactions
There is limited information regarding Sodium hypochlorite Drug Interactions in the drug label.

# Use in Specific Populations

### Pregnancy
Pregnancy Category (FDA):
- Pregnancy Category
Pregnancy Category (AUS):
- Australian Drug Evaluation Committee (ADEC) Pregnancy Category
- There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Sodium hypochlorite in women who are pregnant.

### Labor and Delivery
- There is no FDA guidance on use of Sodium hypochlorite during labor and delivery.

### Nursing Mothers
- There is no FDA guidance on the use of Sodium hypochlorite with respect to nursing mothers.

### Pediatric Use
- There is no FDA guidance on the use of Sodium hypochlorite with respect to pediatric patients.

### Geriatic Use
- There is no FDA guidance on the use of Sodium hypochlorite with respect to geriatric patients.

### Gender
- There is no FDA guidance on the use of Sodium hypochlorite with respect to specific gender populations.

### Race
- There is no FDA guidance on the use of Sodium hypochlorite with respect to specific racial populations.

### Renal Impairment
- There is no FDA guidance on the use of Sodium hypochlorite in patients with renal impairment.

### Hepatic Impairment
- There is no FDA guidance on the use of Sodium hypochlorite in patients with hepatic impairment.

### Females of Reproductive Potential and Males
- There is no FDA guidance on the use of Sodium hypochlorite in women of reproductive potentials and males.

### Immunocompromised Patients
- There is no FDA guidance one the use of Sodium hypochlorite in patients who are immunocompromised.

# Administration and Monitoring

### Administration
Directions
- Pour on or apply to affected area. For wound management, use as an irrigant, cleanser, or the wetting agent for a wet-to-moist dressing. Apply once daily for lightly to moderately exudative wounds. Apply twice daily for highly exudative or highly contaminated wounds. Protect surrounding intact skin with a moisture barrier ointment or skin sealant as needed.

### Monitoring
- There is limited information regarding Monitoring of Sodium hypochlorite in the drug label.

# IV Compatibility
- There is limited information regarding IV Compatibility of Sodium hypochlorite in the drug label.

# Overdosage
There is limited information regarding Sodium hypochlorite overdosage.  If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.

# Pharmacology

## Mechanism of Action
There is limited information regarding Sodium hypochlorite Mechanism of Action in the drug label.

## Structure
There is limited information regarding Sodium hypochlorite Structure in the drug label.

## Pharmacodynamics
- There is limited information regarding Pharmacodynamics of Sodium hypochlorite in the drug label.

## Pharmacokinetics
- There is limited information regarding Pharmacokinetics of Sodium hypochlorite in the drug label.

## Nonclinical Toxicology
- There is limited information regarding Nonclinical Toxicology of Sodium hypochlorite in the drug label.

# Clinical Studies
- There is limited information regarding Clinical Studies of Sodium hypochlorite in the drug label.

# How Supplied

## Storage
- Store at room temperature.
- May bleach clothing.
- Keep container closed when not using.

# Images

## Drug Images

## Package and Label Display Panel

# Patient Counseling Information
- There is limited information regarding Patient Counseling Information of Sodium hypochlorite in the drug label.

# Precautions with Alcohol
- Alcohol-Sodium hypochlorite interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

# Brand Names

# Look-Alike Drug Names
- A  B

# Drug Shortage Status

# Price