Amino acid response element gene transcriptions
"Many amino acid transporters contain an amino acid response element (AARE) in their promoters (27).  Inspection of the regulatory elements of ASCT1 showed a consensus AARE upstream of the transcriptional start site ."

# Human genes
Gene ID: 6509 is SLC1A4 solute carrier family 1 member 4 aka ASCT1 on 2p14: "The protein encoded by this gene is a sodium-dependent neutral amino acid transporter for alanine, serine, cysteine, and threonine. Defects in this gene have been associated with developmental delay, microcephaly, and intellectual disability."

# Gene expressions
Gene ID: 6509 has broad "expression in brain (RPKM 33.8), adrenal (RPKM 12.8) and 23 other tissues".

# Interactions
Gene ID: 6509 interacts with Gene ID: 27161 AGO2 argonaute RISC catalytic component 2.

# Consensus sequences
AARE1 (5'-ATTGCATCA-3')
5'-TTTGCATCA-3'.

# Promoter occurrences
"Inspection of the regulatory elements of ASCT1 showed a consensus AARE upstream of the transcriptional start site ."

# Hypotheses
- A1BG has no Amino acid response elements in either promoter.
- A1BG is not transcribed by an Amino acid response element.
- Amino acid response element does not participate in the transcription of A1BG.

# AARE (Maruyama) samplings
Copying a responsive elements consensus sequence 5'-ATTGCATCA-3' and putting the sequence in "F" finds none between ZNF497 and A1BG or none between ZSCAN22 and A1BG as can be found by the computer programs.
For the Basic programs testing consensus sequence 5'-ATTGCATCA-3' (starting with SuccessablesARE.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found:
- negative strand, negative direction, looking for 5'-ATTGCATCA-3', 0.
- negative strand, positive direction, looking for 5'-ATTGCATCA-3', 0.
- positive strand, negative direction, looking for 5'-ATTGCATCA-3', 0.
- positive strand, positive direction, looking for 5'-ATTGCATCA-3', 0.
- complement, negative strand, negative direction, looking for 5'-TAACGTAGT-3', 0.
- complement, negative strand, positive direction, looking for 5'-TAACGTAGT-3', 0.
- complement, positive strand, negative direction, looking for 5'-TAACGTAGT-3', 0.
- complement, positive strand, positive direction, looking for 5'-TAACGTAGT-3', 0.
- inverse complement, negative strand, negative direction, looking for 5'-TGATGCAAT-3', 0.
- inverse complement, negative strand, positive direction, looking for 5'-TGATGCAAT-3', 0.
- inverse complement, positive strand, negative direction, looking for 5'-TGATGCAAT-3', 0.
- inverse complement, positive strand, positive direction, looking for 5'-TGATGCAAT-3', 0.
- inverse negative strand, negative direction, looking for 5'-ACTACGTTA-3', 0.
- inverse negative strand, positive direction, looking for 5'-ACTACGTTA-3', 0.
- inverse positive strand, negative direction, looking for 5'-ACTACGTTA-3', 0.
- inverse positive strand, positive direction, looking for 5'-ACTACGTTA-3', 0.

# AARE-like samplings
Copying a responsive elements consensus sequence 5'-TGGTGAAAG-3' and putting the sequence in "F" finds none between ZNF497 and A1BG or none between ZSCAN22 and A1BG as can be found by the computer programs.
AARE-like sequence (5-TGGTGAAAG-3, named AARE3)
For the Basic programs testing consensus sequence 5'-TGGTGAAAG-3' (starting with SuccessablesAREL.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found:
- negative strand, negative direction, looking for 5'-TGGTGAAAG-3', 0.
- negative strand, positive direction, looking for 5'-TGGTGAAAG-3', 0.
- positive strand, negative direction, looking for 5'-TGGTGAAAG-3', 0.
- positive strand, positive direction, looking for 5'-TGGTGAAAG-3', 0.
- complement, negative strand, negative direction, looking for 5'-ACCACTTTC-3', 0.
- complement, negative strand, positive direction, looking for 5'-ACCACTTTC-3', 0.
- complement, positive strand, negative direction, looking for 5'-ACCACTTTC-3', 0.
- complement, positive strand, positive direction, looking for 5'-ACCACTTTC-3', 0.
- inverse complement, negative strand, negative direction, looking for 5'-CTTTCACCA-3', 0.
- inverse complement, negative strand, positive direction, looking for 5'-CTTTCACCA-3', 0.
- inverse complement, positive strand, negative direction, looking for 5'-CTTTCACCA-3', 0.
- inverse complement, positive strand, positive direction, looking for 5'-CTTTCACCA-3', 0.
- inverse negative strand, negative direction, looking for 5'-GAAAGTGGT-3', 0.
- inverse negative strand, positive direction, looking for 5'-GAAAGTGGT-3', 0.
- inverse positive strand, negative direction, looking for 5'-GAAAGTGGT-3', 0.
- inverse positive strand, positive direction, looking for 5'-GAAAGTGGT-3', 0.

# AARE (Garaeva) samplings
Copying a responsive elements consensus sequence 5'-TTTGCATCA-3' and putting the sequence in "F" finds none between ZNF497 and A1BG or none between ZSCAN22 and A1BG as can be found by the computer programs.
For the Basic programs testing consensus sequence 5'-TTTGCATCA-3' (starting with SuccessablesAREG.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found:
- negative strand, negative direction, looking for 5'-TTTGCATCA-3', 0.
- negative strand, positive direction, looking for 5'-TTTGCATCA-3', 0.
- positive strand, negative direction, looking for 5'-TTTGCATCA-3', 0.
- positive strand, positive direction, looking for 5'-TTTGCATCA-3', 0.
- complement, negative strand, negative direction, looking for 5'-AAACGTAGT-3', 0.
- complement, negative strand, positive direction, looking for 5'-AAACGTAGT-3', 0.
- complement, positive strand, negative direction, looking for 5'-AAACGTAGT-3', 0.
- complement, positive strand, positive direction, looking for 5'-AAACGTAGT-3', 0.
- inverse complement, negative strand, negative direction, looking for 5'-TGATGCAAA-3', 0.
- inverse complement, negative strand, positive direction, looking for 5'-TGATGCAAA-3', 0.
- inverse complement, positive strand, negative direction, looking for 5'-TGATGCAAA-3', 0.
- inverse complement, positive strand, positive direction, looking for 5'-TGATGCAAA-3', 0.
- inverse negative strand, negative direction, looking for 5'-ACTACGTTT-3', 0.
- inverse negative strand, positive direction, looking for 5'-ACTACGTTT-3', 0.
- inverse positive strand, negative direction, looking for 5'-ACTACGTTT-3', 0.
- inverse positive strand, positive direction, looking for 5'-ACTACGTTT-3', 0.

# Acknowledgements
The content on this page was first contributed by: Henry A. Hoff.