UTR promoter gene transcriptions
"The 3 UTR of eEF1A contains a putative  PRE sequence (TGTAAAT), suggesting that it is a Nanos/Pumilio target."

# Human genes

# Gene expressions

# Interactions

# Consensus sequences

# 3' UTR binding sites
"Wilms tumor 1 (WT1) is essential for the development and homeostasis of multiple mesodermal tissues. Despite evidence for post-transcriptional roles, no endogenous WT1 target RNAs exist. Using RNA immunoprecipitation and UV cross-linking, we show that WT1 binds preferentially to 3 untranslated regions (UTRs) of developmental targets."
Recurrent "kmers occurring in 3 UTRs were identified in the single-read FLASH data. The polyadenylation signal  AATAAA had the highest Z-score, and three similar sequences were also found in the top 10 kmers. However, on correlation with down-regulation, the TGTAAAT motif was found by MEME (Bailey and Elkan 1994) at 294 sites (E-value 2.7  10562), which is different from the motif identified by RIP-seq ."

# 5' UTR binding sites
"We identified high-confidence transcription factor binding sites specific for AP-1, proximal to our putative TSSs within the 5 UTR, consistent with published reports of its role in Gja1 expression (data not shown; Echetebu et al., 1999, Geimonen et al., 1998, Geimonen et al., 1996, Hernandez et al., 2006, Tacheau et al., 2008)."

# Complement copies

# Inverse copies

# Complement-inverse copies

# Enhancer activity

# Promoter occurrences

# Hypotheses
- A1BG has no regulatory elements in either promoter.
- A1BG is not transcribed by a regulatory element.
- No regulatory element participates in the transcription of A1BG.

# TGTAAAT samplings
Copying a responsive elements consensus sequence TGTAAAT and putting the sequence in "F" finds none between ZNF497 and A1BG or none between ZSCAN22 and A1BG as can be found by the computer programs.
For the Basic programs testing consensus sequence TGTAAAT (starting with SuccessablesTGT.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found:
- negative strand, negative direction, looking for TGTAAAT, 1, TGTAAAT at 4535.
- positive strand, negative direction, looking for TGTAAAT, 0.
- positive strand, positive direction, looking for TGTAAAT, 0.
- negative strand, positive direction, looking for TGTAAAT, 0.
- complement, negative strand, negative direction, looking for ACATTTA, 0.
- complement, positive strand, negative direction, looking for ACATTTA, 1, ACATTTA at 4535.
- complement, positive strand, positive direction, looking for ACATTTA, 0.
- complement, negative strand, positive direction, looking for ACATTTA, 0.
- inverse complement, negative strand, negative direction, looking for ATTTACA, 0.
- inverse complement, positive strand, negative direction, looking for ATTTACA, 0.
- inverse complement, positive strand, positive direction, looking for ATTTACA, 0.
- inverse complement, negative strand, positive direction, looking for ATTTACA, 0.
- inverse negative strand, negative direction, looking for TAAATGT, 0.
- inverse positive strand, negative direction, looking for TAAATGT, 0.
- inverse positive strand, positive direction, looking for TAAATGT, 0.
- inverse negative strand, positive direction, looking for TAAATGT, 0.

## TGT UTRs
Negative strand, negative direction, looking for TGTAAAT, 1, TGTAAAT at 4535.

# TGT random dataset samplings
- TGTr0: 0.
- TGTr1: 0.
- TGTr2: 0.
- TGTr3: 0.
- TGTr4: 1, TGTAAAT at 4184.
- TGTr5: 1, TGTAAAT at 3715.
- TGTr6: 0.
- TGTr7: 0.
- TGTr8: 2, TGTAAAT at 2947, TGTAAAT at 2502.
- TGTr9: 0.
- TGTr0ci: 0.
- TGTr1ci: 0.
- TGTr2ci: 1, ATTTACA at 3619.
- TGTr3ci: 0.
- TGTr4ci: 0.
- TGTr5ci: 0.
- TGTr6ci: 1, ATTTACA at 4374.
- TGTr7ci: 0.
- TGTr8ci: 1, ATTTACA at 197.
- TGTr9ci: 0.

## TGTr arbitrary (evens) (4560-2846) UTRs
- TGTr4: TGTAAAT at 4184.
- TGTr8: TGTAAAT at 2947.
- TGTr2ci: ATTTACA at 3619.
- TGTr6ci: ATTTACA at 4374.

## TGTr alternate (odds) (4560-2846) UTRs
- TGTr5: TGTAAAT at 3715.

## TGTr alternate positive direction (evens) (4445-4265) core promoters
- TGTr6ci: ATTTACA at 4374.

## TGTr alternate positive direction (evens) (4265-4050) proximal promoters
- TGTr4: TGTAAAT at 4184.

## TGTr arbitrary negative direction (evens) (2596-1) distal promoters
- TGTr8: TGTAAAT at 2502.
- TGTr8ci: ATTTACA at 197.

## TGTr arbitrary positive direction (odds) (4050-1) distal promoters
- TGTr5: TGTAAAT at 3715.

## TGTr alternate positive direction (evens) (4050-1) distal promoters
- TGTr8: TGTAAAT at 2947, TGTAAAT at 2502.
- TGTr2ci: ATTTACA at 3619.
- TGTr8ci: ATTTACA at 197.

# TGT analysis and results
"The 3 UTR of eEF1A contains a putative  PRE sequence (TGTAAAT), suggesting that it is a Nanos/Pumilio target."
Comparison:
The occurrences of a real TGT is greater than the randoms. This suggests that the real TGT is likely active or activable.

# Acknowledgements
The content on this page was first contributed by: Henry A. Hoff.