Infectious Disease Project Antimicrobial Agents

# WikiDoc Infectious Disease Project  Antimicrobial Agents
Drug Categories: 
Antibacterial   
Antimycobacterial   
Antiparasitic   
Antifungal   
Antiviral   
Antiretroviral
Alphabetical List: 
A   
B   
C   
D   
E   
F   
G   
H   
I   
K   
L   
M   
N   
O   
P   
Q   
R   
S   
T   
V   
Z
Generic vs. Pharmaceutical Names:  
Generic Name  Pharmaceutical Name    
Pharmaceutical Name  Generic Name
Risk Categories in Pregnancy: 
Antibacterial    
Antimycobacterial    
Antifungal    
Antiparasitic    
Antiviral    
FDA Pregnancy Categories
Risk Categories for TdP or QTc Interval Prolongation    
CYP450 Isozymes Drug Interactions: Substrates, Inhibitors, Inducers
Antimicrobial Spectrum, Dosing Information, Adverse Reaction    
Dosage Adjustment in Renal or Hepatic Impairment

# Antimicrobial Agents by Category

# Antimicrobial Agents in Alphabetical Order

# Generic Names and Pharmaceutical Names

## Generic Name  Pharmaceutical Name Return to Top

## Pharmaceutical Name  Generic Name Return to Top

# Antimicrobial Spectrum, Dosing Information, Adverse Reaction

## Antimicrobial Spectrum, Dosing Information, and Adverse Reaction Return to Top

# Risk Categories of Antimicrobial Agents in Pregnancy

## Risk Categories of Antibacterial Agents in Pregnancy Return to Top

## Risk Categories of Antimycobacterial Agents in Pregnancy Return to Top

## Risk Categories of Antifungal Agents in Pregnancy Return to Top

## Risk Categories of Antiparasitic Agents in Pregnancy Return to Top

## Risk Categories of Antiviral Agents in Pregnancy Return to Top

## FDA Pregnancy Categories Return to Top

# Risk Categories of Antimicrobial Agents for TdP or QTc Interval Prolongation

## Risk categories for antimicrobial agents known to have an association with TdP Return to Top
- Drugs with known TdP risk
- Azithromycin (Zithromax, Zmax)
- Chloroquine (Aralen)
- Ciprofloxacin (Cipro, Cipro-XR, Neofloxin)
- Clarithromycin (Biaxin, Prevpac)
- Erythromycin (A/T/S, Akne-Mycin, Emgel, Ery-Tab, Eryc, Erycette, Eryderm, Erygel)
- Fluconazole (Diflucan, Trican)
- Halofantrine (Halfan)
- Levofloxacin (Levaquin, Tavanic)
- Moxifloxacin (Avelox, Avalox, Avelon)
- Pentamidine (Pentam)
- Sparfloxacin (Zagam)
- Drugs with possible TdP risk
- Atazanavir (Reyataz)
- Bedaquiline (Sirturo)
- Dihydroartemisinin-Piperaquine (Eurartesim)
- Foscarnet (Foscavir)
- Gatifloxacin (Tequin)
- Gemifloxacin (Factive)
- Norfloxacin (Noroxin, Ambigram)
- Ofloxacin (Floxin)
- Rilpivirine (Edurant, Complera, Eviplera)
- Roxithromycin (Rulide, Xthrocin, Roxl-150, Roxo, Surlid, Rulide, Biaxsig, Roxar, Roximycinv, Roxomycin, Rulid, Tirabicin, Coroxin)
- Saquinavir (Invirase(combo))
- Telavancin (Vibativ)
- Telithromycin (Ketek)
- Drugs with conditional TdP risk
- Amantadine (Symmetrel, Symadine)
- Hydroxychloroquine (Plaquenil, Quineprox)
- Itraconazole (Sporanox, Onmel)
- Ketoconazole (Nizoral, Sebizole, Ketomed, Keton)
- Metronidazole (Flagyl and many others)
- Nelfinavir (Viracept)
- Posaconazole (Noxafil, Posamol)
- Quinine sulfate (Qualaquin)
- Ritonavir (Norvir)
- Telaprevir (Incivek, Incivo)
- Voriconazole (VFend)
- Drugs to be avoided by congenital Long QT
- Trimethoprim-Sulfamethoxazole (Septra, Bactrim, Sulfatrim, Biseptol, Co-trimoxazole, Cotrim, Septrin, Trisul)

## Torsades de pointes risk stratification schedules for antimicrobial agents Return to Top
- Schedule I (Highest TdP risk, potent IKr blockers, TdP risk >1%)
- Not available
- Schedule II (Significant risk for TdP, particularly when coadministered with CYP inhibitors, relatively potent IKr blockade)
- Not available
- Schedule III (Risk for TdP is described, IKr blockade, particularly when coadministered with CYP inhibitors)
- Clarithromycin (Biaxin, Prevpac)
- Erythromycin (A/T/S, Akne-Mycin, Emgel, Ery-Tab, Eryc, Erycette, Eryderm, Erygel)
- Itraconazole (Sporanox, Onmel)
- Ketoconazole (Nizoral, Sebizole, Ketomed, Keton)
- Pentamidine (Pentam)
- Sparfloxacin (Zagam)
- Schedule IV (Minimal risk for TdP, case reports of TdP, mild IKr blockade, may have CYP interactions)
- Fluconazole (Diflucan, Trican)
- Gatifloxacin (Tequin)
- Gemifloxacin (Factive)
- Levofloxacin (Levaquin, Tavanic)
- Moxifloxacin (Avelox, Avalox, Avelon)
- Telithromycin (Ketek)
- Voriconazole (VFend)
- Schedule V (Questionable or minimal risk for QT interval prolongation or TdP)
- Azithromycin (Zithromax, Zmax)
- Ciprofloxacin (Cipro, Cipro-XR, Neofloxin)
- Trimethoprim-Sulfamethoxazole (Septra, Bactrim, Sulfatrim, Biseptol, Co-trimoxazole, Cotrim, Septrin, Trisul)

# CYP450 Isozymes Drug Interactions

## Substrates of Cytochrome P-450 Isozymes

## Inhibitors of Cytochrome P-450 Isozymes

## Inducers of Cytochrome P-450 Isozymes

# Dosage Adjustment in Renal or Hepatic Impairment

## Dosage adjustment in renal impairment Return to Top

### Renal dose of antimicrobial agents (consult FDA package insert for details):

## Dosage adjustment in hepatic impairment Return to Top

### Hepatic dose of antimicrobial agents (consult FDA package insert for details):