Peroxisome proliferator hormone response element gene transcriptions
"After activation by ligands, PPARs/RXRs heterodimers bind to PPRE consensus sequence (AGGTCANAGGTCA) in the promoter of their target genes."
Peroxisome proliferator hormone response elements (PPREs) consensus sequences are AGGGGA and TCCCCT.

# Human genes

# Consensus sequences
The DNA consensus sequence is AGGTCANAGGTCA, with N being any nucleotide.

# PPRE samplings
For the Basic programs testing consensus sequence AGGTCANAGGTCA (starting with SuccessablesPPRE.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found:
- negative strand, negative direction, looking for AGGTCANAGGTCA, 0.
- positive strand, negative direction, looking for AGGTCANAGGTCA, 0.
- positive strand, positive direction, looking for AGGTCANAGGTCA, 0.
- negative strand, positive direction, looking for AGGTCANAGGTCA, 0.
- complement, negative strand, negative direction, looking for TCCAGTNTCCAGT, 0.
- complement, positive strand, negative direction, looking for TCCAGTNTCCAGT, 0.
- complement, positive strand, positive direction, looking for TCCAGTNTCCAGT, 0.
- complement, negative strand, positive direction, looking for TCCAGTNTCCAGT, 0.
- inverse complement, negative strand, negative direction, looking for TGACCTNTGACCT, 0.
- inverse complement, positive strand, negative direction, looking for TGACCTNTGACCT, 0.
- inverse complement, positive strand, positive direction, looking for TGACCTNTGACCT, 0.
- inverse complement, negative strand, positive direction, looking for TGACCTNTGACCT, 0.
- inverse negative strand, negative direction, looking for ACTGGANACTGGA, 0.
- inverse positive strand, negative direction, looking for ACTGGANACTGGA, 0.
- inverse positive strand, positive direction, looking for ACTGGANACTGGA, 0.
- inverse negative strand, positive direction, looking for ACTGGANACTGGA, 0.

# PPARA consensus sequences
Consensus sequence is 5'-CGACCCC-3'.

# PPARA samplings
Copying the apparent consensus sequence for the PPARA (CGACCCC) and putting it in "F" finds one located between ZSCAN22 and none between ZNF497 and A1BG as can be found by the computer programs.
For the Basic programs testing consensus sequence CGACCCC (starting with Successables PPARA.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found:
- negative strand, negative direction, looking for CGACCCC, 1, CGACCCC at 3037.
- positive strand, negative direction, looking for CGACCCC, 0.
- positive strand, positive direction, looking for CGACCCC, 1, CGACCCC at 279.
- negative strand, positive direction, looking for CGACCCC, 0.
- complement, negative strand, negative direction, looking for GCTGGGG, 0.
- complement, positive strand, negative direction, looking for GCTGGGG, 1, GCTGGGG at 3037.
- complement, positive strand, positive direction, looking for GCTGGGG, 0.
- complement, negative strand, positive direction, looking for GCTGGGG, 1, GCTGGGG at 279.
- inverse complement, negative strand, negative direction, looking for GGGGTCG, 1, GGGGTCG at 2766.
- inverse complement, positive strand, negative direction, looking for GGGGTCG, 0.
- inverse complement, positive strand, positive direction, looking for GGGGTCG, 0.
- inverse complement, negative strand, positive direction, looking for GGGGTCG, 0.
- inverse negative strand, negative direction, looking for CCCCAGC, 0.
- inverse positive strand, negative direction, looking for CCCCAGC, 1, CCCCAGC at 2766.
- inverse positive strand, positive direction, looking for CCCCAGC, 0.
- inverse negative strand, positive direction, looking for CCCCAGC, 0.

## PPARA (4560-2846) UTRs
- Negative strand, negative direction: CGACCCC at 3037.

## PPARA negative direction (2811-2596) proximal promoters
- Negative strand, negative direction: GGGGTCG at 2766.

## PPARA positive direction (4050-1) distal promoters
- Positive strand, positive direction: CGACCCC at 279.

# PPARA random dataset samplings
- PPARAr0: 2, CGACCCC at 4084, CGACCCC at 3906.
- PPARAr1: 0.
- PPARAr2: 0.
- PPARAr3: 0.
- PPARAr4: 0.
- PPARAr5: 1, CGACCCC at 3597.
- PPARAr6: 1, CGACCCC at 2956.
- PPARAr7: 1, CGACCCC at 2415.
- PPARAr8: 1, CGACCCC at 1108.
- PPARAr9: 0.
- PPARAr0ci: 0.
- PPARAr1ci: 1, GGGGTCG at 2011.
- PPARAr2ci: 0.
- PPARAr3ci: 0.
- PPARAr4ci: 0.
- PPARAr5ci: 0.
- PPARAr6ci: 0.
- PPARAr7ci: 0.
- PPARAr8ci: 2, GGGGTCG at 1741, GGGGTCG at 246.
- PPARAr9ci: 0.

## PPARAr arbitrary (evens) (4560-2846) UTRs
- PPARAr0: CGACCCC at 4084, CGACCCC at 3906.
- PPARAr6: CGACCCC at 2956.

## PPARAr alternate (odds) (4560-2846) UTRs
- PPARAr5: CGACCCC at 3597.

## PPARAr alternate positive direction (evens) (4265-4050) proximal promoters
- PPARAr0: CGACCCC at 4084.

## PPARAr arbitrary negative direction (evens) (2596-1) distal promoters
- PPARAr8: CGACCCC at 1108.
- PPARAr8ci: GGGGTCG at 1741, GGGGTCG at 246.

## PPARAr alternate negative direction (odds) (2596-1) distal promoters
- PPARAr7: CGACCCC at 2415.
- PPARAr1ci: GGGGTCG at 2011.

## PPARAr arbitrary positive direction (odds) (4050-1) distal promoters
- PPARAr5: CGACCCC at 3597.
- PPARAr7: CGACCCC at 2415.
- PPARAr1ci: GGGGTCG at 2011.

## PPARAr alternate positive direction (evens) (4050-1) distal promoters
- PPARAr0: CGACCCC at 3906.
- PPARAr6: CGACCCC at 2956.
- PPARAr8: CGACCCC at 1108.
- PPARAr8ci: GGGGTCG at 1741, GGGGTCG at 246.

# PPARA analysis and results
Consensus sequence is CGACCCC.
Comparison:
The occurrences of real PPARA UTRs and negative direction proximals are greater than the randoms, the positive direction distal overlaps the upper end of the randoms. This suggests that the real PPARAs are likely active or activable.