Hyaluronic acid (intraarticular)

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# Overview
Hyaluronic acid (intraarticular) is a cartilaginous defect repair agent that is FDA approved for the treatment of osteoarthritis of knee.   Common adverse reactions include injection site pain, injection site reaction, arthralgia.

# Adult Indications and Dosage

## FDA-Labeled Indications and Dosage (Adult)
For the treatment of Osteoarthritis of knee

## Off-Label Use and Dosage (Adult)

### Guideline-Supported Use
There is limited information regarding Off-Label Guideline-Supported Use of Hyaluronic acid (intraarticular) in adult patients.

### NonGuideline-Supported Use
There is limited information regarding Off-Label NonGuideline-Supported Use of Hyaluronic acid (intraarticular) in adult patients.

# Pediatric Indications and Dosage

## FDA-Labeled Indications and Dosage (Pediatric)
There is limited information regarding FDA-Labeled Use of Hyaluronic acid (intraarticular) in pediatric patients.

## Off-Label Use and Dosage (Pediatric)

### Guideline-Supported Use
There is limited information regarding Off-Label Guideline-Supported Use of Hyaluronic acid (intraarticular) in pediatric patients.

### NonGuideline-Supported Use
There is limited information regarding Off-Label NonGuideline-Supported Use of Hyaluronic acid (intraarticular) in pediatric patients.

# Contraindications
There is limited information regarding Hyaluronic acid (intraarticular) Contraindications in the drug label.

# Warnings
There is limited information regarding Hyaluronic acid (intraarticular) Warnings' in the drug label.

# Adverse Reactions

## Clinical Trials Experience
There is limited information regarding Clinical Trial Experience of Hyaluronic acid (intraarticular) in the drug label.

## Postmarketing Experience
There is limited information regarding Postmarketing Experience of Hyaluronic acid (intraarticular) in the drug label.

# Drug Interactions
There is limited information regarding Hyaluronic acid (intraarticular) Drug Interactions in the drug label.

# Use in Specific Populations

### Pregnancy
Pregnancy Category (FDA): 
There is no FDA guidance on usage of Hyaluronic acid (intraarticular) in women who are pregnant.
Pregnancy Category (AUS): 
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Hyaluronic acid (intraarticular) in women who are pregnant.

### Labor and Delivery
There is no FDA guidance on use of Hyaluronic acid (intraarticular) during labor and delivery.

### Nursing Mothers
There is no FDA guidance on the use of Hyaluronic acid (intraarticular) with respect to nursing mothers.

### Pediatric Use
There is no FDA guidance on the use of Hyaluronic acid (intraarticular) with respect to pediatric patients.

### Geriatic Use
There is no FDA guidance on the use of Hyaluronic acid (intraarticular) with respect to geriatric patients.

### Gender
There is no FDA guidance on the use of Hyaluronic acid (intraarticular) with respect to specific gender populations.

### Race
There is no FDA guidance on the use of Hyaluronic acid (intraarticular) with respect to specific racial populations.

### Renal Impairment
There is no FDA guidance on the use of Hyaluronic acid (intraarticular) in patients with renal impairment.

### Hepatic Impairment
There is no FDA guidance on the use of Hyaluronic acid (intraarticular) in patients with hepatic impairment.

### Females of Reproductive Potential and Males
There is no FDA guidance on the use of Hyaluronic acid (intraarticular) in women of reproductive potentials and males.

### Immunocompromised Patients
There is no FDA guidance one the use of Hyaluronic acid (intraarticular) in patients who are immunocompromised.

# Administration and Monitoring

### Administration
- Intraarticular

### Monitoring
There is limited information regarding Monitoring of Hyaluronic acid (intraarticular) in the drug label.

# IV Compatibility
There is limited information regarding IV Compatibility of Hyaluronic acid (intraarticular) in the drug label.

# Overdosage
There is limited information regarding Chronic Overdose of Hyaluronic acid (intraarticular) in the drug label.

# Pharmacology

## Mechanism of Action
There is limited information regarding Hyaluronic acid (intraarticular) Mechanism of Action in the drug label.

## Structure
There is limited information regarding Hyaluronic acid (intraarticular) Structure in the drug label.

## Pharmacodynamics
There is limited information regarding Pharmacodynamics of Hyaluronic acid (intraarticular) in the drug label.

## Pharmacokinetics
There is limited information regarding Pharmacokinetics of Hyaluronic acid (intraarticular) in the drug label.

## Nonclinical Toxicology
There is limited information regarding Nonclinical Toxicology of Hyaluronic acid (intraarticular) in the drug label.

# Clinical Studies
There is limited information regarding Clinical Studies of Hyaluronic acid (intraarticular) in the drug label.

# How Supplied
- 3mL in a 10mL Single Use Syringe.
- Store at 20 to 25C (68 to 77F). . Protect from freezing.

## Storage
There is limited information regarding Hyaluronic acid (intraarticular) Storage in the drug label.

# Images

## Drug Images

## Package and Label Display Panel

# Patient Counseling Information
There is limited information regarding Patient Counseling Information of Hyaluronic acid (intraarticular) in the drug label.

# Precautions with Alcohol
Alcohol-Hyaluronic acid (intraarticular) interaction has not been established. Talk to your doctor regarding the effects of taking alcohol with this medication.

# Brand Names
There is limited information regarding Hyaluronic acid (intraarticular) Brand Names in the drug label.

# Look-Alike Drug Names
There is limited information regarding Hyaluronic acid (intraarticular) Look-Alike Drug Names in the drug label.

# Drug Shortage Status

# Price