Procainamide Oral (patient information)

# IMPORTANT WARNING
Antiarrhythmic drugs, including procainamide, may increase the risk of death. Tell your doctor if you have had a heart attack within the past two years. Procainamide should be used only to treat life-threatening arrhythmias (irregular heartbeats).
Procainamide may cause a decrease in the number of cells in your bone marrow. Procainamide may also cause symptoms of lupus.
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to procainamide.
If you experience any of the following symptoms, call your doctor immediately: fever, chills, sore throat, bruising, bleeding, muscle aches or weakness, stomach or chest pain, skin rash, or blisters on the cheek, tongue and lips.
Talk to your doctor about the risks of taking procainamide.

# Why this medication is prescribed
Procainamide is used to treat abnormal heart rhythms. It works by making your heart more resistant to abnormal activity.

# How this medication should be used
Procainamide comes as a capsule and tablet to take by mouth. Immediate-acting procainamide usually is taken every 3 or 4 hours. The long-acting product is usually taken every 6 or 12 hours. Do not cut, crush, or chew extended-release (long-acting) tablets; swallow them whole. You may see a waxy core in your stool if you are taking the extended-release product; this is normal.
Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take procainamide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Procainamide helps control your condition but will not cure it. Continue to take procainamide even if you feel well. Do not stop taking procainamide without talking to your doctor.

# Other uses for this medicine
This medication should not be prescribed for other uses; ask your doctor or pharmacist for more information.

# Special Precautions
Before taking procainamide:
- tell your doctor and pharmacist if you are allergic to procainamide, anesthetics, aspirin, or any other drugs.
- tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially digoxin (Lanoxin) or drugs for high blood pressure, and vitamins.
- in addition to the condition listed in the IMPORTANT WARNING section, tell your doctor if you have or have ever had lupus, heart disease, high blood pressure, kidney or liver disease, or myasthenia gravis.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking procainamide, call your doctor.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking procainamide.
- you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how this drug affects you.
- remember that alcohol can add to the drowsiness caused by this drug.
- talk to your doctor about the use of cigarettes and caffeine-containing beverages. These products may increase the irritability of your heart and interfere with the action of procainamide.

# What to do if you forget a dose
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

# Side Effects

## Minor Side Effects
Procainamide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- dizziness or lightheadedness
- loss of appetite
- upset stomach
- vomiting
- bitter taste

## Severe Side Effects
If you experience the following symptom or any of those listed in the IMPORTANT WARNING section, call your doctor immediately:
- irregular heartbeat
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online  or by phone .

# Storage conditions needed for this medication
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

# In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

# Other information
Keep all appointments with your doctor and the laboratory. Your doctor will need to determine your response to procainamide.
Take procainamide at the same time each day in regularly spaced intervals. Changing the time of your doses prevents procainamide from working effectively.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

# Brand names
- Procanbid