Chromosome 14 (human)
Chromosome 14 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 14 spans about 107 million base pairs (the building material of DNA) and represents between 3 and 3.5% of the total DNA in cells.
The centromere of chromosome 14 is positioned approximately at position 17.2 Mbp.

# Genes
The following are some of the gene count estimates of human chromosome 14. Because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies (for technical details, see gene prediction). Among various projects, the collaborative consensus coding sequence project (CCDS) takes an extremely conservative strategy. So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes.
The following are some of the genes located on chromosome 14:
- ACIN1: encoding protein Apoptotic chromatin condensation inducer in the nucleus
- ATXN3: Ataxin-3 (Machado-Joseph disease)
- C14orf1: encoding protein Probable ergosterol biosynthetic protein 28
- C14orf93: encoding protein C14orf93
- C14orf133: encoding protein Uncharacterized protein C14orf133
- C14orf159: encoding protein UPF0317 protein C14orf159, mitochondrial
- C14orf166: encoding protein UPF0568 protein C14orf166
- C14orf169: encoding protein Chromosome 14 open reading frame 169
- C14orf32/MAPK1IP1L: encoding protein MAPK-interacting and spindle-stabilizing protein-like
- C14orf39: encoding protein Chromosome 14 open reading frame 39
- C14orf4: encoding protein Enhanced at puberty protein 1
- C14orf79: encoding protein Uncharacterized protein C14orf79
- CDC42BPB: encoding protein CDC42 binding protein kinase beta
- CHMP4A: Charged multivesicular body protein 4a
- CIDEB: Cell death-inducing DFFA-like effector b
- CMA1: encoding enzyme Chymase
- CNIH: encoding protein Protein cornichon homolog
- COCH: coagulation factor C homolog, cochlin (Limulus polyphemus)
- CRIP2: Cysteine-rich protein 2
- DDX24: encoding enzyme ATP-dependent RNA helicase DDX24
- DEGS2: encoding protein Delta(4)-desaturase, sphingolipid 2
- DLGAP5: Disks large-associated protein 5
- EAPP: E2F-associated phosphoprotein
- EGLN3: Egl nine homolog 3
- ENTPD5: Ectonucleoside triphosphate diphosphohydrolase 5
- Fam158a: encoding protein UPF0172 protein FAM158A
- FAM181A: encoding protein Family with sequence similarity 181, member A
- FAM71D: Family With Sequence Similarity 71, Member D
- FCF1: rRNA-processing protein FCF1 homolog
- GALC: galactosylceramidase (Krabbe disease)
- GARNL1: GTPase-activating Rap/Ran-GAP domain-like 1
- GCH1: GTP cyclohydrolase 1 (dopa-responsive dystonia)
- GPHB5: Glycoprotein hormone beta-5
- GSKIP encoding protein GSK3B interacting protein
- HHIPL1: encoding protein HHIP-like protein 1
- IFI27: encoding protein Interferon alpha-inducible protein 27
- IFT43: intraflagellar transport 43
- IGH@: immunoglobulin heavy chain locus
- ITPK1: encoding enzyme Inositol-tetrakisphosphate 1-kinase
- JKAMP: encoding protein JNK1-associated membrane protein
- JPH4: encoding protein Junctophilin 4
- LINC00520: a long non-coding RNA
- MIA2: encoding protein Melanoma inhibitory activity protein 2
- MIR494 encoding protein MicroRNA 494
- MIR3173: encoding protein MicroRNA 3173
- MIS18BP1: encoding protein MIS18 binding protein 1
- MOAP1: encoding protein Modulator of apoptosis 1
- MYH7: myosin heavy chain beta (MHC-) isoform
- NPC2: Niemann-Pick disease, type C2
- NUBPL: encoding protein Iron-sulfur protein NUBPL (IND1)
- OSGEP: encoding enzyme Probable O-sialoglycoprotein endopeptidase
- PAPOLA: encoding enzyme Poly(A) polymerase alpha
- PCNX: encoding protein Pecanex-like protein 1
- PELI2: encoding protein Protein pellino homolog 2
- PSEN1: presenilin 1 (Alzheimer disease 3)
- RPL10L: encoding protein 60S ribosomal protein L10-like
- SERPINA1: serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
- SGPP1: encoding enzyme Sphingosine-1-phosphate phosphatase 1
- TC2N: encoding protein Tandem C2 domains nuclear protein
- TCL1B: encoding protein T-cell leukemia/lymphoma protein 1B
- TIMM9: encoding enzyme Mitochondrial import inner membrane translocase subunit Tim9
- TMED10: encoding protein Transmembrane emp24 domain-containing protein 10
- TMEM260: encoding protein TMEM260
- TRAJ56 encoding protein T cell receptor alpha joining 56
- TSHR: thyroid stimulating hormone receptor
- TUNAR: a long non-coding RNA
- VASH1: encoding protein Vasohibin-1
- WARS: encoding enzyme Tryptophanyl-tRNA synthetase, cytoplasmic
- YLPM1: encoding protein YLP motif-containing protein 1
- ZBTB1: encoding protein Zinc finger and BTB domain containing 1
- ZFHX2: encoding protein Zinc finger homeobox 2
- ZNF839: encoding protein Zinc finger protein 839

# Diseases and disorders
The following diseases are some of those related to genes on chromosome 14:
- alpha-1 antitrypsin deficiency
- Alzheimer disease
- Burkitt's lymphoma (t8;14)
- congenital hypothyroidism
- dopamine-responsive dystonia
- Follicular lymphoma (t14;18)
- Hypertrophic cardiomyopathy
- Krabbe disease
- Craniolenticulosutural dysplasia
- Machado-Joseph disease
- Mosaic monosomy 14
- Multiple myeloma
- Niemann-Pick disease
- Nonsyndromic deafness
- Sensenbrenner syndrome
- Tetrahydrobiopterin deficiency
- Uniparental disomy (UPD) 14

# Cytogenetic band