Office Action 2: Notice of Allowance (2025-02-28)

CLAIMS:
AMENDMENTS TO THE CLAIMS

1\. (Currently Amended) A data acquisition module for a system for measuring a nasal valve collapse of a patient, wherein the data acquisition module comprises a processor that is configured to:
receive a plurality of images of a nasal valve from a camera of an endoscope positioned through an endoscope port of a facial mask and a plurality of air flow measurements from an air flow sensor configured to measure an air flow across an opening in the facial mask;
determine (i) a first image of the plurality of images of the nasal valve taken during inhalation and (ii) a second image of the plurality of images of the nasal valve taken during a period between exhalation and inhalation, wherein the second image is synchronized with a zero flow measurement of the plurality of air flow measurements, wherein the first image is synchronized with a non-zero flow measurement of the plurality of air flow measurements; and
determine, based on the first image and the second image, a size difference of the nasal valve during inhalation and during the period between exhalation and inhalation.

2\. (Currently Amended) The data acquisition module of claim 1, wherein, to determine the size difference of the nasal valve, the processor is configured to:
determine, based on the first image, a first distance between a septum and a lateral wall of the nasal valve during inhalation,2

determine, based on the second image, a second distance between the septum and the lateral wall of the nasal valve during the period between exhalation and inhalation, and
determine the size difference by dividing the first distance by the second distance.

3\. (Original) The data acquisition module of claim 1, wherein the plurality of images are taken during a plurality of inhalation rates,
wherein the plurality of inhalation rates are different from each other, and wherein the data acquisition module is further configured to, for each inhalation rate, determine a relative distance between a septum and a lateral wall of the nasal valve.
4\. (Currently Amended) The data acquisition module of claim 3, wherein the processor is configured to communicate with an external computing device to cause display of a graph of (i) the relative distances between the septum and the lateral wall of the nasal valve at the plurality of inhalation rates versus (ii) the air flow measurements at the plurality of inhalation rates.

5\. (Currently Amended) The data acquisition module of claim 1, wherein the processor is further configured to:
receive an annotation of the first image of the nasal valve during inhalation, wherein the annotation of the first image indicates a distance between a septum and a lateral wall of the nasal valve in the first image;3

determining a first distance between the septum and the lateral wall based on the annotation of the first image of the nasal valve during inhalation;
receive an annotation of the second image of the nasal valve during the period between exhalation and inhalation, wherein the annotation of the second image indicates a distance between the septum and the lateral wall of the nasal valve in the second image; and
determine a second distance between the septum and the lateral wall based on the annotation of the second image of the nasal valve during the period between exhalation and inhalation; and
determine the size difference of the nasal valve based on the first distance and the second distance.

6\. (Currently Amended) The data acquisition module of claim 1, wherein the processor is configured to apply image analysis to the first image to automatically measure an area of space between a septum and a lateral wall to automatically determine an area or a length of the septum and a lateral wall.

7\. (Currently Amended) The data acquisition module of claim 1, wherein the processor is configured to receive the plurality of images as video captured by the camera.

8\. (Canceled)

9\. (Canceled)4

10\. (Canceled)

11\. (Canceled)

12\. (Canceled)

13\. (Canceled)

14\. (Canceled)

15\. (Currently Amended) A method of measuring a nasal valve collapse by a data acquisition module comprising a processor, the method comprising:
receiving, at a processor of a data acquisition module, a plurality of images of a nasal valve from a camera of an endoscope positioned through an endoscope port of a facial mask and a plurality of air flow measurements from an air flow sensor configured to measure an air flow across an opening in the facial mask,
determining, by the processor, (i) a first image of the plurality of images of the nasal valve taken during inhalation and (ii) a second image of the plurality of images of the nasal valve taken during a period between exhalation and inhalation, wherein the second image is synchronized with a zero flow measurement of the plurality of air flow measurements, wherein 5

HULBERT&BERGHOFF LLP 300SOUTHWACKERDRIVE CHICAGO, ILLINOIS 60606 TELEPHONE (312) 913-0001 the first image is synchronized by the processor with a non-zero flow measurement of the plurality of air flow measurements, and
determining, based on the first image and the second image, a size difference of the nasal valve during inhalation and during the period between exhalation and inhalation.

16\. (Original) The method of claim 15, wherein, determining the size difference of the nasal valve comprises:
determining, based on the first image, a first distance between a septum and a lateral wall of the nasal valve during inhalation,
determining, based on the second image, a second distance between the septum and the lateral wall of the nasal valve during the period between exhalation and inhalation, and
determining the size difference by dividing the first distance by the second distance.

17\. (Original) The method of claim 15, wherein the plurality of images are taken during a plurality of inhalation rates,
wherein the plurality of inhalation rates are different from each other, and wherein the method further comprises, for each inhalation rate, determining a relative distance between a septum and a lateral wall of the nasal valve.

18\. (Original) The method of claim 17, further comprising communicating with an external computing device to cause display of a graph of (i) the relative distances between the 6

septum and the lateral wall of the nasal valve at the plurality of inhalation rates versus (ii) the air flow measurements at the plurality of inhalation rates.

19\. (Original) The method of claim 15, further comprising:
receiving an annotation of the first image of the nasal valve during inhalation, wherein the annotation of the first image indicates a distance between a septum and a lateral wall of the nasal valve in the first image;
determining a first distance between the septum and the lateral wall based on the annotation of the first image of the nasal valve during inhalation;
receiving an annotation of the second image of the nasal valve during the period between exhalation and inhalation, wherein the annotation of the second image indicates a distance between the septum and the lateral wall of the nasal valve in the second image; and
determining a second distance between the septum and the lateral wall based on the annotation of the second image of the nasal valve during the period between exhalation and inhalation; and
determining the size difference of the nasal valve based on the first distance and the second distance.

20\. (Original) The method of claim 15, further comprising applying image analysis to the first image to automatically measure an area of space between a septum and a lateral wall to automatically determine an area or a length of the septum and a lateral wall.7

21\. (New) The method of claim 15, further comprising synchronizing the plurality of images from the camera and the plurality of air flow measurements from the air flow sensor using a plurality of time stamps associated with the plurality of images and the plurality of air flow measurements.

22\. (New) The method of claim 15, wherein determining the size difference of the nasal valve during inhalation and during the period between exhalation and inhalation comprises calculating, based on the first image and the second image, a percentage difference in an area or one or more dimensions of the nasal valve between the first image and the second image

23\. (New) The method of claim 15, further comprising causing a display device to display a graphical user interface, an image of the plurality of images taken at a first time, and an airflow measurement taken at the first time.

24\. (New) The method of claim 15, further comprising causing a display device to display a graph including the plurality of air flow measurements versus time.

25\. (New) The data acquisition module of claim 1, wherein the processor is further configured to synchronize the plurality of images from the camera and the plurality of air flow measurements from the air flow sensor using a plurality of time stamps associated with the plurality of images and the plurality of air flow measurements.

26\. (New) The data acquisition module of claim 1, wherein the processor is configured to determine the size difference of the nasal valve during inhalation and during the 8

period between exhalation and inhalation by calculating, based on the first image and the second image, a percentage difference in an area or one or more dimensions of the nasal valve between the first image and the second image.

27\. (New) The data acquisition module of claim 1, wherein the processor is configured to cause a display device to display a graph including the plurality of air flow measurements versus time.9

HULBERT&BERGHOFF LLP 300SOUTHWACKERDRIVE CHICAGO, ILLINOIS 60606 TELEPHONE (312) 913-0001

OFFICE ACTION:
Reasons for Allowance
The following is an examiner’s statement of reasons for allowance: the amendments filed on 02/03/2025 have overcome the rejections within the previous Office Action. Specifically, claims 1-7 have been amended and overcome the 35 USC 101 rejection; claims 8-14 were canceled and thus there is no 35 USC 101 rejection to be made; and claims 15-20 have been amended to overcome the 35 USC 101 rejection. The filing and Approval of a Terminal Disclaimer, on 02/03/2025, for US PATs 11,642,043 B2, 11,957,448 B2, and 10,987,024 B2 overcomes the Double Patenting Rejections made within the previous Office Action. Since the only rejections made in the previous Office Action were 35 USC 101 rejections and Double Patenting rejections, and this issues have been resolved, the claims are allowable. None of the prior art, either alone or in combination, teaches each and every limitation within the claim language and thus the claims are allowable.
Claims 1-7 and 15-27 are allowed.
Any comments considered necessary by applicant must be submitted no later than the payment of the issue fee and, to avoid processing delays, should preferably accompany the issue fee.  Such submissions should be clearly labeled “Comments on Statement of Reasons for Allowance.”
Conclusion

APPLICANT REBUTTAL: REMARKS
I.
of the Office Action
In the Office Action dated August 1, 2024, the Examiner:
(i)   rejected claims 1-20 under 35 U.S.C. § 101 as allegedly being directed to non- statutory subject matter;
(ii)  rejected claims 1-20 on the ground of nonstatutory double patenting as allegedly being unpatentable over claims 1-4, 7, 14, and 15 of U.S. Pat. No. 11,642,043; (iii) rejected claims 1-20 on the ground of nonstatutory double patenting as allegedly being unpatentable over claims 1-4, 7, 13, and 14 of U.S. Pat. No. 11,957,448;
-17 on the ground of nonstatutory doublepatenting as allegedly being unpatentable over claims 1, 2, and 4 of U.S. Pat. No. 10,987,024; and
(v)   indicated that claims 1-20 would be allowable if the 35 U.S.C. § 101 and Double Patenting rejections were overcome.
of Claims
Claims 1-20 are pending. In this response, Applicant has (a) amended claims 1-2, 4-7, and 15, (b) canceled claims 8-14, and (c) added claims 21-27. After entry of this amendment,
-27 will be pending.
III. Examiner Interview
Applicant's representative would like to thank Examiner Vanchy for the telephonic interview on January 30, 2025. During the interview, the participants discussed proposed
MCDONNELL BOEHNEN
amendments to independent claims 1, 8, and 15 in view of the rejections under 35 U.S.C. § 101.
The Examiner agreed that the proposed amendments to claims 1 and 15 would overcome the current rejections. No agreement was reached with respect to the proposed amendment to
independent claim 8.
IV.   Response to the Rejections Under 35 U.S.C. § 101
As indicated above, the Office rejected claims 1-20 under 35 U.S.C. § 101 as allegedly being directed to non-statutory subject matter.
In this response, Applicant has amended independent claims 1 and 15 as discussed during the interview, and canceled independent claim 8. Accordingly, as agreed during the interview,
amended claims 1-7 and 15-20 are directed to statutory subject matter.
V.    Response to the Double Patenting Rejection
As indicated above, the Office (i) rejected claims 1-20 on the ground of nonstatutory double patenting as allegedly being unpatentable over claims 1-4, 7, 14, and 15 of U.S. Pat. No.
11,642,043, (ii) rejected claims 1-20 on the ground of nonstatutory double patenting as allegedly being unpatentable over claims 1-4, 7, 13, and 14 of U.S. Pat. No. 11,957,448, and (iii) rejected claims 1-3, 8-10, and 15-17 on the ground of nonstatutory double patenting as allegedly being
unpatentable over claims 1, 2, and 4 of U.S. Pat. No. 10,987,024.
To overcome this rejection, a Terminal Disclaimer is submitted herewith. This Terminal Disclaimer should not be construed as an admission to the merits of the nonstatutory double
MCDONNELL BOEHNEN
patenting rejections pursuant to Quad Environmental Technologies Corp. v. Union Sanitary
District, 946 F.2d 870 (Fed. Cir. 1991); see also MPEP § 804.02.
In view of the Terminal Disclaimer, Applicant respectfully requests withdrawal of the rejection of claims 1-3, 5, 11-13, and 15-17 on the ground of nonstatutory double patenting.
VI.    Allowable Subject Matter
As indicated above, the Office indicated that claims 1-20 would be allowable if the 35 U.S.C. § 101 and Double Patenting rejections were overcome. Applicant thanks the Examiner
for the indication of allowable subject matter.
VII. Conclusion


CITED REFERENCE SUMMARIES: Ref US11957448B2: Claims:
A system for measuring a nasal valve collapse of a patient comprising: a facial mask adapted to form a seal with a facial structure of the patient, the facial mask including an endoscope port and an opening to allow air flow; an air flow sensor in fluid communication with the opening of the facial mask configured to measure an air flow across the opening; an endoscope with a camera adapted to pass through the endoscope port in the facial mask and image a nasal valve; and a data acquisition module configured to: receive a plurality of images from the camera and a plurality of air flow measurements from the air flow sensor, determine (i) a first image of the plurality of images of the nasal valve taken during inhalation and (ii) a second image of the plurality of images of the nasal valve taken during a period between exhalation and inhalation, wherein the second image is determined based on a zero flow measurement of the plurality of air flow measurements, wherein the first image is determined based on a non-zero flow measurement of the plurality of air flow measurements, and determine, based on the first image and the second image, a size difference of the nasal valve during inhalation and during the period between exhalation and inhalation.
a facial mask adapted to form a seal with a facial structure of the patient, the facial mask including an endoscope port and an opening to allow air flow;
an air flow sensor in fluid communication with the opening of the facial mask configured to measure an air flow across the opening;
an endoscope with a camera adapted to pass through the endoscope port in the facial mask and image a nasal valve; and a data acquisition module configured to: receive a plurality of images from the camera and a plurality of air flow measurements from the air flow sensor, determine (i) a first image of the plurality of images of the nasal valve taken during inhalation and (ii) a second image of the plurality of images of the nasal valve taken during a period between exhalation and inhalation, wherein the second image is determined based on a zero flow measurement of the plurality of air flow measurements, wherein the first image is determined based on a non-zero flow measurement of the plurality of air flow measurements, and determine, based on the first image and the second image, a size difference of the nasal valve during inhalation and during the period between exhalation and inhalation.
a data acquisition module configured to:
receive a plurality of images from the camera and a plurality of air flow measurements from the air flow sensor,
determine (i) a first image of the plurality of images of the nasal valve taken during inhalation and (ii) a second image of the plurality of images of the nasal valve taken during a period between exhalation and inhalation, wherein the second image is determined based on a zero flow measurement of the plurality of air flow measurements, wherein the first image is determined based on a non-zero flow measurement of the plurality of air flow measurements, and
determine, based on the first image and the second image, a size difference of the nasal valve during inhalation and during the period between exhalation and inhalation.
The system of claim 1 , wherein, to determine the size difference of the nasal valve, the data acquisition module is configured to: determine, based on the first image, a first distance between a septum and a lateral wall of the nasal valve during inhalation, determine, based on the second image, a second distance between the septum and the lateral wall of the nasal valve during the period between exhalation and inhalation, and determine the size difference by dividing the first distance by the second distance.
determine, based on the first image, a first distance between a septum and a lateral wall of the nasal valve during inhalation,
determine, based on the second image, a second distance between the septum and the lateral wall of the nasal valve during the period between exhalation and inhalation, and
determine the size difference by dividing the first distance by the second distance.
The system of claim 1 , wherein the plurality of images are taken during a plurality of inhalation rates, wherein the plurality of inhalation rates are different from each other, and wherein the data acquisition module is further configured to, for each inhalation rate, determine a relative distance between a septum and a lateral wall of the nasal valve.
wherein the plurality of inhalation rates are different from each other, and
wherein the data acquisition module is further configured to, for each inhalation rate, determine a relative distance between a septum and a lateral wall of the nasal valve.
The system of claim 3 , further comprising a display device that is configured to display a graph of (i) the relative distances between the septum and the lateral wall of the nasal valve at the plurality of inhalation rates versus (ii) the air flow measurements at the plurality of inhalation rates.
The system of claim 1 , further comprising a display device configured to display a graphical user interface, GUI.
The system of claim 5 , wherein the graphical user interface, GUI, is configured to display (i) an image of the plurality of images taken at a first time and (ii) an air flow measurement measured at the first time.
The system of claim 5 , wherein the data acquisition module is further configured to: receive an annotation of the first image of the nasal valve during inhalation, wherein the annotation of the first image indicates a distance between a septum and a lateral wall of the nasal valve in the first image; determine a first distance between the septum and the lateral wall based on the annotation of the first image of the nasal valve during inhalation; receive an annotation of the second image of the nasal valve during the period between exhalation and inhalation, wherein the annotation of the second image indicates a distance between the septum and the lateral wall of the nasal valve in the second image; and determine a second distance between the septum and the lateral wall based on the annotation of the second image of the nasal valve during the period between exhalation and inhalation; and determine the size difference of the nasal valve based on the first distance and the second distance.
receive an annotation of the first image of the nasal valve during inhalation, wherein the annotation of the first image indicates a distance between a septum and a lateral wall of the nasal valve in the first image;
determine a first distance between the septum and the lateral wall based on the annotation of the first image of the nasal valve during inhalation;
receive an annotation of the second image of the nasal valve during the period between exhalation and inhalation, wherein the annotation of the second image indicates a distance between the septum and the lateral wall of the nasal valve in the second image; and
determine a second distance between the septum and the lateral wall based on the annotation of the second image of the nasal valve during the period between exhalation and inhalation; and
determine the size difference of the nasal valve based on the first distance and the second distance.
The system of claim 7 , wherein the graphical user interface, GUI, is configured to display the annotation of the first image and the annotation of the second image.
The system of claim 7 , wherein the annotation of the first image comprises a line across the nasal valve between the lateral wall and the septum in the first image, and the annotation of the second image comprises a line across the nasal valve between the lateral wall and the septum in the second image.
The system of claim 7 , wherein the annotation of the first image comprises a tracing of a perimeter of the nasal valve in the first image, and the annotation of the second image comprises a tracing of the perimeter of the nasal valve in the second image.
The system of claim 5 , wherein the graphical user interface, GUI, is configured to display a graph including the air flow measurements versus time.
The system of claim 11 , wherein the graphical user interface, GUI, is configured to: receive an input from a user indicating a time of interest on the graph; and display an image of the plurality of images of the nasal valve that was taken at the time of interest.
receive an input from a user indicating a time of interest on the graph; and
display an image of the plurality of images of the nasal valve that was taken at the time of interest.
The system of claim 1 , wherein the data acquisition module is configured to apply image analysis to the first image to automatically measure an area of space between a septum and a lateral wall to automatically determine an area or a length of the septum and a lateral wall.
The system of claim 1 , wherein the camera is configured to capture the plurality of images as a video of the nasal valve.
The system of claim 1 , wherein the data acquisition module is configured to synchronize the plurality of images from the camera and the plurality of air flow measurements from the air flow sensor using a plurality of time stamps associated with the plurality of images and the plurality of air flow measurements.
The system of claim 1 , wherein the facial mask is adapted to engage with the facial structure of the patient without changing a nasal anatomy of the patient.
The system of claim 1 , wherein the data acquisition module is configured to determine the size difference of the nasal valve during inhalation and during the period between exhalation and inhalation by calculating, based on the first image and the second image, a percentage difference in an area or one or more dimensions of the nasal valve between the image of the nasal valve taken during inhalation and the image of the nasal valve during zero flow.
The system of claim 1 , further comprising an external computing device communicating with the data acquisition module, wherein the external computing device comprises a display having a graphical user interface (GUI) for display of patient data.
The system of claim 18 , wherein the graphical user interface (GUI) is configured to display a degree of nasal valve collapse simultaneously with air flow passing through the nasal valve.
The system of claim 1 , wherein the endoscope port is located at a bottom of the facial mask and comprises a sealed port.
Ref US11642043B2: Claims:
A system for measuring a nasal valve collapse of a patient comprising: a facial mask adapted to form a seal with a facial structure of the patient, the facial mask including an endoscope port and an opening to allow air flow; an air flow sensor in fluid communication with the opening of the facial mask configured to measure an air flow across the opening; an endoscope with a camera adapted to pass through the endoscope port in the facial mask and image a nasal valve; and a data acquisition module configured to: receive a plurality of images from the camera and a plurality of air flow measurements from the air flow sensor, determine, based on the air flow measurements, (i) a first image of the plurality of images of the nasal valve taken during inhalation and (ii) a second image of the plurality of images of the nasal valve taken during a period between exhalation and inhalation, and determine, based on the first image and the second image, a size difference of the nasal valve during inhalation and during the period between exhalation and inhalation.
a facial mask adapted to form a seal with a facial structure of the patient, the facial mask including an endoscope port and an opening to allow air flow;
an air flow sensor in fluid communication with the opening of the facial mask configured to measure an air flow across the opening;
an endoscope with a camera adapted to pass through the endoscope port in the facial mask and image a nasal valve; and
a data acquisition module configured to: receive a plurality of images from the camera and a plurality of air flow measurements from the air flow sensor, determine, based on the air flow measurements, (i) a first image of the plurality of images of the nasal valve taken during inhalation and (ii) a second image of the plurality of images of the nasal valve taken during a period between exhalation and inhalation, and determine, based on the first image and the second image, a size difference of the nasal valve during inhalation and during the period between exhalation and inhalation.
receive a plurality of images from the camera and a plurality of air flow measurements from the air flow sensor,
determine, based on the air flow measurements, (i) a first image of the plurality of images of the nasal valve taken during inhalation and (ii) a second image of the plurality of images of the nasal valve taken during a period between exhalation and inhalation, and
determine, based on the first image and the second image, a size difference of the nasal valve during inhalation and during the period between exhalation and inhalation.
The system of claim 1 , wherein, to determine the size difference of the nasal valve, the data acquisition module is configured to: determine, based on the first image, a first distance between a septum and a lateral wall of the nasal valve during inhalation, determine, based on the second image, a second distance between the septum and the lateral wall of the nasal valve during the period between exhalation and inhalation, and determine the size difference by dividing the first distance by the second distance.
determine, based on the first image, a first distance between a septum and a lateral wall of the nasal valve during inhalation,
determine, based on the second image, a second distance between the septum and the lateral wall of the nasal valve during the period between exhalation and inhalation, and
determine the size difference by dividing the first distance by the second distance.
The system of claim 1 , wherein the plurality of images are taken during a plurality of inhalation rates, wherein the plurality of inhalation rates are different from each other, and wherein the data acquisition module is further configured to, for each inhalation rate, determine a relative distance between a septum and a lateral wall of the nasal valve.
wherein the plurality of inhalation rates are different from each other, and
wherein the data acquisition module is further configured to, for each inhalation rate, determine a relative distance between a septum and a lateral wall of the nasal valve.
The system of claim 3 , further comprising a display device that is configured to display a graph of (i) the relative distances between the septum and the lateral wall of the nasal valve at the plurality of inhalation rates versus (ii) the air flow measurements at the plurality of inhalation rates.
The system of claim 1 , further comprising a display device configured to display a graphical user interface (GUI).
The system of claim 5 , wherein the graphical user interface (GUI) is configured to display (i) an image of the plurality of images taken at a first time and (ii) an air flow measurement measured at the first time.
The system of claim 5 , wherein the data acquisition module is further configured to: receive an annotation of the first image of the nasal valve during inhalation, wherein the annotation of the first image indicates a distance between a septum and a lateral wall of the nasal valve in the first image; determining a first distance between the septum and the lateral wall based on the annotation of the first image of the nasal valve during inhalation; receive an annotation of the second image of the nasal valve during the period between exhalation and inhalation, wherein the annotation of the second image indicates a distance between the septum and the lateral wall of the nasal valve in the second image; and determine a second distance between the septum and the lateral wall based on the annotation of the second image of the nasal valve during the period between exhalation and inhalation; and determine the size difference of the nasal valve based on the first distance and the second distance.
receive an annotation of the first image of the nasal valve during inhalation, wherein the annotation of the first image indicates a distance between a septum and a lateral wall of the nasal valve in the first image;
determining a first distance between the septum and the lateral wall based on the annotation of the first image of the nasal valve during inhalation;
receive an annotation of the second image of the nasal valve during the period between exhalation and inhalation, wherein the annotation of the second image indicates a distance between the septum and the lateral wall of the nasal valve in the second image; and
determine a second distance between the septum and the lateral wall based on the annotation of the second image of the nasal valve during the period between exhalation and inhalation; and
determine the size difference of the nasal valve based on the first distance and the second distance.
The system of claim 7 , wherein the graphical user interface (GUI) is configured to display the annotation of the first image and the annotation of the second image.
The system of claim 7 , wherein the annotation of the first image comprises a line across the nasal valve between the lateral wall and the septum in the first image, and the annotation of the second image comprises a line across the nasal valve between the lateral wall and the septum in the second image.
The system of claim 7 , wherein the annotation of the first image comprises a tracing of a perimeter of the nasal valve in the first image, and the annotation of the second image comprises a tracing of the perimeter of the nasal valve in the second image.
The system of claim 5 , wherein the graphical user interface (GUI) is configured to display a graph including the air flow measurements versus time.
The system of claim 11 , wherein the graphical user interface (GUI) is configured to: receive an input from a user indicating a time of interest on the graph; and display an image of the plurality of images of the nasal valve that was taken at the time of interest.
receive an input from a user indicating a time of interest on the graph; and
display an image of the plurality of images of the nasal valve that was taken at the time of interest.
The system of claim 5 , wherein the graphical user interface is configured to display a graph of a quantification of the nasal valve collapse at a plurality of inhalation rates versus air flow rate.
The system of claim 1 , wherein the data acquisition module is configured to apply image analysis to the first image to automatically measure an area of space between a septum and a lateral wall to automatically determine an area or a length of the septum and a lateral wall.
The system of claim 1 , wherein the camera is configured to capture the plurality of images as a video of the nasal valve.
The system of claim 1 , wherein the data acquisition module is configured to synchronize the plurality of images from the camera and the plurality of air flow measurements from the air flow sensor using a plurality of time stamps associated with the plurality of images and the plurality of air flow measurements.
The system of claim 1 , wherein the data acquisition module is configured to determine the size difference of the nasal valve during inhalation and during the period between exhalation and inhalation by calculating a percentage difference in an area or one or more dimensions of the nasal valve during inhalation and the period between exhalation and inhalation.
The system of claim 17 , wherein the data acquisition module is configured to determine the size difference of the nasal valve during inhalation and during the period be
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