CRYSTAL STRUCTURE AND ANTICANCERACTIVITY ON RETINOBLASTOMA OF AN In(III)–Na(I) COORDINATION POLYMER BASED ON FLEXIBLE4,4′-DITHIODIBENZOIC ACID
Authors: Peng, Y
Tang, S
Ye, L
Guo, H
Chen, W H
Wang, Y
Wang, L
Zhan, W Z
Journal: Journal of Structural Chemistry (2020)
Discipline: CHEMISTRY
Keywords: bimetallic coordination polymer; hydrothermal reaction; elemental analysis; X-ray diffraction; nanostructure

Abstract: A bimetallic coordination polymer is prepared via a hydrothermal reaction of H2DDBA and In(NO3) water with NaOH as a pH regulator. Its chemical formula is [In2Na(H2O)6(ddba)3](NO3)(H2O)7 (1, H2ddba&nbsp;=&nbsp;4,4′-dithiodibenzoic acid). The composition and atomic arrangement of the prepared complexes are studied by the elemental analysis (EA) and the thermogravimetric analysis (TGA), powder and single crystal X-ray diffraction measurements. Moreover, a process of sonochemistry with oleic acid treatment at 453 K is used to produce nanostructure the biological function detection, a miRNA relative expression is detected via RT-PCR and Bcl-2 expression level is determined with the Western blot. The Annexin V-FITC/PI staining is performed to detect retinoblastoma cell apoptosis after treatment with nano-1.

Retracted: No

PubPeer comments:
 The meaningless irrelevant References, and the appearance of the same meaningless irrelevant References in dozens of other papers, are suggestive of a production-line provenance.  Coordination chemistry has a great latent capacity to provide varieties of compounds that have multiple mechanisms associated with DNA binding, redox reactivity, and different geometries, some of which are specific to metals [3, 4]. - [4]. S. Guo, R. Chen, M. Wei, H. Li, and Y. Liu. IEEE Access, 2018, 6, 45934. ** Ensemble Data Reduction Techniques and Multi-RSMOTE via Fuzzy Integral for Bug Report Classification **  In the past decades, the clinical success of cisplatin along with its analogues has aroused extensive interest in the research of novel metal-based anticancer drugs, however, its drug resistance, general toxicity, and serious side effects have severely limited its application [5]. - [5]. W. Chen, L. Chang, S. B. Ren, Z. C. He, G. B. Huang, and X. H. Liu. J. Hazard. Mater., 2020, 384, 121308. ** Direct Z-scheme 1D 2D WO 2.72 ZnIn 2 S 4 hybrid photocatalysts with highly-efficient visible-light-driven photodegradation towards tetracycline hydrochloride removal **  The miR-16-1 relative expression in cancer cells after treatment with nano 1 was detected by the reverse transcription-polymerase chain reaction according to manufactureu2032s instructions [14]. - [14]. H. Li, G. Gao, R. Chen, X. Ge, S. Guo, and L. Y. Hao. Int. J. Software Eng. Know., 2019, 29, 93. ** The Influence Ranking for Testers in Bug Tracking Systems **  As a mitochondrial outer membrane protein that blocks apoptosis death, the Bcl-2 protein expression level was further measured with the Western blot assay after treating with nano-1 [15]. - [15]. S. Guo, R. Chen, H. Li, T. Zhang, and Y. Liu. Int. J. Software Eng. Know., 2019, 29, 139. ** Identify Severity Bug Report with Distribution Imbalance by CR-SMOTE and ELM ** , 
 Fig 6. It is unclear what the lanes are supposed to represent, but I guess that the bronchial-epithelial cell-line BEAS-2B is for some reason compared with three retinoblastoma cell lines (with and without nano-1?). Two panels are the same, anyway. ![file] , 
 Fig 2d: ![file] Fig 5c from [Qi et al (2019)] : ![file] , 
 Fig 2c: ![] Fig 2d from [Liu et al (2020)] : ![] ,