Lessons Learned from COVID-19 Pandemic in Italy
Authors: Francesca Candelori
Claudio Parlapiano
Lucia Ercoli
Antonio Greco
Massimo Ralli
Antonio Minni
Marco De Vincentiis
Fabrizio Cialente
Journal: Bosnian journal of basic medical sciences (2020)
Discipline: CLINICAL MEDICINE
Keywords: COVID-19 outbreak; Italy; health-care providers; public hospital; infection containment
Affiliations: Department of Sense Organs, University Sapienza of Rome, Italy., Department of Sense Organs, Sapienza University of Rome, Italy., Department of Infective Medicine, Tor Vergata University, Rome, Italy., Department of Clinical Sciences and Internal Medicine, Sapienza University of Rome, Italy., Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Italy.

Abstract:  Since the COVID-19 outbreak, Italy has been one of the most affected countries in Europe and the second for number of deaths. In this commentary, we discuss some lessons that we learned as health-care providers working in a large public hospital during the pandemic, with a special focus on the importance of infection containment and early diagnosis, the role of swab, serological tests, home isolation and individual protection devices, and the available therapies and management indications to better face a possible new outbreak in the near future. These comments should stimulate a more diffused, efficient, and efficacious management of COVID-19 patients, also reducing the number of admissions to hospital emergency departments and the related spread of the infection. 

Retracted: No

PubPeer comments:
 In Figure 2, a micrograph has been duplicated, modified and presented as something else. ![file] , 
 Thankyou for pointing out the inadvertent error. I will investigate it on myside with my co-authors and accordingly contact the editor for necessary action. Regards, , 
 #1 The paper appears to have been revised or corrected, replacing Fig 2, with no indication how that problematic image came into existence. The version currently available through the journal website was created modified on 23 December 2020. Is this the  necessary action promised in Comment #2? ![file] , 
 *[left]* Figure 3 from [Xiao et al (2020)] .  Annexin V PI staining for apoptotic analysis of SCC-1 cancer cells treated with Voacangine. The Figure shows dose-dependent increase in the percentage of apoptotic SCC-1 upon Voacangine treatment . *[right]* Figure 4 from [Yu, Guo Wang (2020)] .  Annexin V FITC PI assay results developed via flow cytometry indicating enhanced early and late apoptotic cells. As the lycopsamine concentration increased the number of necrotic and apoptotic cells increased. ![file] , 
 *[left]* The **replacement** Figure 2.  AO EB staining showing induction of apoptosis of SCC-1 cancer cells treated with Voacangine in a dose-dependent manner . *[right]* Figure 2D from [Li et al (2020)] .  miR-7 induces apoptosis in TPC-1 cancer cells.... D. AO EB staining of cancer cells transfected with miR-NC and miR-7 mimics. ![file] None of this really inspires faith in the integrity of the papers, or the editorial process. , 
 #5 The editors have replaced Fig 2 for a second time, perhaps realising that the first replacement was equally bogus. The panels of the second replacement resemble a bowl of Smarties spilled across a black tabletop. The version of the paper currently provided at the journal website was created on 19 January 2021. ![file] ,