Angelica sinensis polysaccharide protects rat cardiomyocytes H9c2 from hypoxia-induced injury by down-regulation of microRNA-22
Authors: Hui Pan
Linlin Zhu
Journal: Biomedicine & Pharmacotherapy (2018)
Discipline: PHARMACOLOGY & TOXICOLOGY
Keywords: Angelica sinensis; H9c2 cells; Hypoxia; Myocardial infarction; PI3K/AKT/JAK1/STAT3
Affiliations: Department of Cardiology, Affiliated Hospital of Jining Medical University, Jining, Shandong 272000, China., Department of Cardiology, Affiliated Hospital of Jining Medical University, Jining, Shandong 272000, China. Electronic address: .

Abstract:  This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief as there are concerns about the reliability of the results included in the article. The journal was initially contacted by the corresponding author to request the retraction of the article. Given the comments of Dr Elisabeth Bik regarding this article “This paper belongs to a set of over 400 papers (as per February 2020) that share very similar Western blots with tadpole-like shaped bands, the same background pattern, and striking similarities in title structures, paper layout, bar graph design, and - in a subset - flow cytometry panels”, the journal requested the author to provide the raw data. However, the author was not able to fulfil this request and therefore the Editor-in-Chief decided to retract the article. 

Retracted: Yes

PubPeer comments:
 This paper belongs to a set of over 400 papers (as per February 2020) that share very similar Western blots with tadpole-like shaped bands, the same background pattern, and striking similarities in title structures, paper layout, bar graph design, and - in a subset - flow cytometry panels. Despite these similarities, these papers are authored by researchers from different departments and institutes, with almost no overlap in authors. The list of these papers is available here: https: docs.google.com spreadsheets d 1KXqTAyl4j-jVorFPMD2XRpr76LcIKJ0CVyIvRj0exYQ edit?usp=sharing A more detailed description of this set of papers, suspected to all be generated by a common source, a paper mill , can be found here: * https: forbetterscience.com 2020 01 24 the-full-service-paper-mill-and-its-chinese-customers (January 2020) * https: scienceintegritydigest.com 2020 02 21 the-tadpole-paper-mill (February 2020) The same paper mill has been described in these papers: * Jana Christopher - Systematic fabrication of scientific images revealed - FEBS Letters (2018) - https: febs.onlinelibrary.wiley.com doi full 10.1002 1873-3468.13201 * Jennifer A Byrne and Jana Christopher - Digital magic, or the dark arts of the 21st centuryu2014how can journals and peer reviewers detect manuscripts and publications from paper mills? - FEBS Letters (2020) - https: febs.onlinelibrary.wiley.com doi full 10.1002 1873-3468.13747 , 
 A [report from the Affiliated Hospital of Jining Medical College] , from September 30 2021, reads as follows {thanks Google Translate): --------------------------- 14. The issue of  Angelica sinensis polysaccharide protects rat cardiomyocytes H9c2 from hypoxia-induced injury by down-regulation of microRNA-22 written by Zhu Linlin of the Affiliated Hospital of Jining Medical College as the corresponding author. After investigation, the paper  Angelica sinensis polysaccharide protects rat cardiomyocytes H9c2 from hypoxia-induced injury by down-regulation of microRNA-22 in the paper  Angelica sinensis polysaccharide protects rat cardiomyocytes H9c2 from hypoxia-induced injury by down-regulation of microRNA-22 , written by Zhu Linlin as the corresponding author and Pan Hui as the first author, contains fraudulent papers. problem. The Affiliated Hospital of Jining Medical College will deal with the relevant responsible persons as follows: 1. Give the corresponding author Zhu Linlin (1) order him to make an in-depth inspection; (2) order him to withdraw the manuscript of the paper involved; (3) cancel the five-year application for science and technology plan projects (special projects, funds, etc.), science and technology awards, science and technology projects Talent titles and other qualifications, from March 2, 2020 to March 1, 2025; (4) Cancellation of five-year postgraduate tutor application and appointment qualifications from March 2, 2020 to March 2025 1 day; (5) Cancellation of three-year professional title promotion qualifications from March 2, 2020 to March 1, 2023; (6) Criticism is reported in the hospital. 2. The first author Pan Hui will be (1) ordered to make a deep inspection; (2) the five-year application for scientific and technological plan projects (special projects, funds, etc.), scientific and technological awards, and the title of scientific and technological talents will be cancelled, starting from March 2020 From March 2, 2025 to March 1, 2025; (3) cancel the five-year postgraduate tutor application and appointment qualifications, from March 2, 2020 to March 1, 2025; (4) cancel the three-year professional title Qualification for promotion, from March 2, 2020 to March 1, 2023; (5) Criticisms are reported in the hospital. ------------------------------------- Could the journal editors confirm that they have received a request to withdraw the paper? , 
 Retracted [25 March 2022] . ----------------- This article has been retracted at the request of the Editor-in-Chief as there are concerns about the reliability of the results included in the article. The journal was initially contacted by the corresponding author to request the retraction of the article. Given the comments of Dr Elisabeth Bik regarding this article u201cThis paper belongs to a set of over 400 papers (as per February 2020) that share very similar Western blots with tadpole-like shaped bands, the same background pattern, and striking similarities in title structures, paper layout, bar graph design, and - in a subset - flow cytometry panelsu201d, the journal requested the author to provide the raw data. However, the author was not able to fulfil this request and therefore the Editor-in-Chief decided to retract the article. ,