Two Metal Complexes: Selective Detection of Fe3+ Ion and Promotion Activity on Mesenchymal Stem Cells Differentiate Into Vascular Endothelial Cells
Authors: Qin-Ming Zhao
Yu-Xiang He
Mo Wang
Hui-Peng Zhu
Zhong-You Xu
Journal: Journal of Fluorescence (2021)
Discipline: CHEMISTRY
Keywords: Coordination polymer; Fluorescence quenching; Mesenchymal stem cells; Vascular endothelial growth factor.
Affiliations: Department of Vascular Surgery, The Affiliated People's Hospital of Ningbo University, Ningbo, Zhejiang, China. ., Department of Vascular Surgery, The Affiliated People's Hospital of Ningbo University, Ningbo, Zhejiang, China., Department of Chemistry, Shandong Medical University, Jinan, Shandong, China.

Abstract:  With the aid of 1,2-bis(4-pyridyl)ethane (bpee), a nitrogen-donor ligand and 1,3,5-tris(carboxymethoxy)benzene (H3TCMB), a tripodal ether-connector tricarboxylate ligand, two novel transition metal coordination polymers (CPs) have been synthesized via the reaction of Zn(NO3)2·6H2O or Cu(NO3)2·3H2O with the ligands of H3TCMB and bpee ligands with similar reactions under slightly distinct temperatures (80℃ for 1 and 120℃ for 2), and their chemical formula are [Cu4(TCMB)2(bpee)2(µ3-OH)2(H2O)2]n·12nH2O (1) and [Zn4(TCMB)2(bpee)2(µ3-OH)2(H2O)2]n·12nH2O (2). Complex 2 can be utilized as a super sensitive fluorescence quenching sensor to determine the Fe3+ ions. The effect of these two compounds on the differentiation of mesenchymal stem cells (MSCs) into the cells of vascular endothelial was further explored. 

Retracted: No

PubPeer comments:
  In the past few years, the self-assembly for the coordination polymers (CPs) consisted of organic connectors and metal nodes has received much attention not only for due to the latent discovery of fresh functional materials, which contains latent applications in ion-exchange, molecular sieves, and gas storage, optoelectronics, biomedicine as well as catalysis, but also because of their fascinating topologies and structures, for instance, herringbones, bricks, and molecular grids, boxes, rings, and ladders and honeycombs [4u20139] Are these really examples of coordination polymers? - [4]. Yuan D, Sun M, Zhao M, Tang S, Qi J, Zhang X, Wang K, Li B (2020) Persulfate promoted ZnIn2S4 visible light photocatalytic dye decomposition. Int J Electrochem Sci 15:8761u20138770 - [5]. Jiang N, Liu Y, Yu XN, Zhang HB, Wang MM (2020) Corrosion resistance of Nickel-Phosphorus Nano-ZnO composite multilayer coating electrodeposited on carbon steel in acidic chloride environments. Int J Electrochem Sci 15:5520u20135528  In general, the symmetric rigid multiu2010topic ligands have been studied in depth for possible more predictable supramolecular structures, but their diversity is limited in part because no or few conformational changes can be found in the metal ions treatment of such ligands [10u201313]. - [10]. Duan C, Su Z, Cao Y, Hu L, Fu D, Ma J, Zhang Y (2021) Synthesis of core-shell u03b1-AlH3@Al(OH)3 nanocomposite with improved low-temperature dehydriding properties by mechanochemical mixing and ionic liquid treatment. J Clean Prod 283:124635 , 
  In short, the MSCs in the **phage of logical growth** were harvested and inoculated into plates of 6 well at 10^6 cells each well destiny ![file] The authors do not specify the **source** of the mesenchymal stem cells that they cultivated in an unspecified culture medium and persuaded to differentiate into vascular endothelial cells. Animal? Human? Their own? ,