Long non-coding RNA LINC00460 promotes epithelial ovarian cancer progression by regulating microRNA-338-3p
Authors: Xiaoxia Liu
Yanli Wang
Jihong Wen
Haijiao Wang
Journal: Biomedicine & Pharmacotherapy (2018)
Discipline: PHARMACOLOGY & TOXICOLOGY
Keywords: Epithelial ovarian cancer; LINC00460; LncRNA; miR-338-3p.
Affiliations: Department of Gynecology, The First Hospital of Jilin University, Changchun 130021, China., Department of Gynecology, The First Hospital of Jilin University, Changchun 130021, China. Electronic address: .

Abstract:  This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief and the authors. Panels from Figures 2C and 2D appear similar to panels from Figures 4D and 4F of the article published by Hai-Xiang Yu, Xiao-Long Wang, Le-Ning Zhang, Ji Zhang and Wei Zhao in Biomedicine &amp; Pharmacotherapy 109 (2019) 751-761 https://doi.org/10.1016/j.biopha.2018.09.110. Panels from Figure 3B appear similar to panels from Figure 3D of the article previously published by Yuanyuan Meng, Qi Li, Lianwei Li and Rong Ma in Biological Chemistry 399 (2017) 93-100 https://doi.org/10.1515/hsz-2017-0199. The ‘GAPDH’ Western Blots from Figure 3C appear similar to the ‘AKT’ Western Blots from Figure 6 of the article previously published by Lan Wu, Bo Shi, Kexin Huang and Guoyu Fan in the Oncology Reports 34 (2015) 2797-2805 https://doi.org/10.3892/or.2015.4251 and the ‘GAPDH’ Western Blots from Figure 4D of the article previously published by Tao Peng, Lixiang Zhou, Ling Zuo and Yongxin Luan in the Oncology Reports 35 (2016) 1057-1064 https://doi.org/10.3892/or.2015.4406. 

Retracted: Yes

PubPeer comments:
 At right: Figure 4,  SDSu2013PAGE analysis of ligand anchored nanoparticles. Lane 1: molecular weight marker of 225 kD, lane 2: naive hepatitis B antigen, lane 3: naive LTA lectin, lane 4: lectin anchored PLGA nanoparticles stabilized without trehalose, lane 5: lectin anchored PLGA nanoparticles stabilized with trehalose. At left: Figure 5 from [Mishra et al (2014)] .  SDS-PAGE analysis of ligand-anchored nanoparticles. Lane 1: Molecular weight marker of 225 kDa, Lane 2: Naive hepatitis B antigen, Lane 3: Naive LTA lectin and Lane 4: Lectin anchored Chitosan nanoparticles. ![file] A single molecular-weight ladder has been spliced into both blots. Other bands are also recognisable, one rotated through 180 deg. , 
 Figure 6.  Confocal laser scanning microscopy images showing targeting of the nanoparticles to the M cells of the Peyeru2019s patches in mice by dual staining. M cells were primarily stained with TRITC-WGA (red). FITCu2013LTA coupled PLGA nanoparticles stain green. Control nanoparticles (FITCu2013BSA coated) showed little or no binding to M cells (A). Lectinized nanoparticles (shown by arrow) were associated predominantly with M cells (B). ![file] Figure 7 from Mishra et al (2014).  Confocal laser scanning microscopy images showing targeting of the nanoparticles to the M cells of the Peyeru2019s patches in mice by dual staining. M cells were primarily stained with TRITC-WGA (red). FITC-LTA coupled Chitosan nanoparticles stain green. Control nanoparticles (FITC-BSA coated) shows little or no binding to M cells (A). Lectinized chitosan nanoparticles (shown by arrow) were associated predominantly with M cells (B).  ![file] The images appear to be the same (with more green background in the 2011 version), although these are different studies, with the NPs composed of PLGA here and of chitosan in 2014. , 
 #2 Fig 6 again,  Control nanoparticles (FITCu2013BSA coated) showed little or no binding to M cells (A). Lectinized nanoparticles (shown by arrow) were associated predominantly with M cells (B). Is it possible that instead of different groups of cells, the same group of cells has been displayed by mistake in (A) and (B), slightly differently processed? I have highlighted areas of green background (FITCu2013LTA coupled PLGA nanoparticles) where the similarity is especially striking. ![file] The same applies, of course, to the appearance of the same images in [Mishra et al (2014)] , except that the green background is much less intense there. The first appearance of 6B (180-deg rotated) was as Fig 1A of [Tiwari Vyas (2011)] , where alas the nature of the NPs was unspecified. ![] ,