MiR-361-5p inhibits the mobility of gastric cancer cells through suppressing epithelial-mesenchymal transition via the Wnt/β-catenin pathway
Authors: Lei Tian
JinPeng Zhu
Ling Xie
Zhifeng Zhao
Journal: Gene (2018)
Discipline: MOLECULAR BIOLOGY & GENETICS
Keywords: EMT; Gastric cancer; MiR-361-5p; Wnt/β-catenin.
Affiliations: Department Gastroenterol, Jinzhou Medical University, Affilliated Hospital 1, Jinzhou 121000, Liaoning Province, PR China. Electronic address: ., Department Gastroenterol, Zhongguo Medical University, Affilliated Hospital 4, Shengyang 110000, Liaoning Province, PR China., Department Anatomy, Jinzhou Medical University, Jinzhou 121000, Liaoning Province, PR China., Department Gastroenterol, Jinzhou Medical University, Affilliated Hospital 1, Jinzhou 121000, Liaoning Province, PR China.

Abstract:  This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). Several figures presented in the manuscript appear to have been doctored. Figure 1C contains copied areas between the Control group and miR-361-5p mock panels. An area from Figure 1C miR-361-5p mock panel is copied from Figure 2B lncRNA-MEG3 panel from the publication Oncology Reports 39-48, 2018 doi:10.3892/or.2018.6424 Figure 1D contains copied areas between the Control group and miR-361-5p mock panels. Figures 1E and 1F show several copied areas between one other. At higher contrast, the western blot presented in Figure 3G shows signs of picture manipulation The journal has tried to contact the authors of this article but at the time of publication of this notice has not received any explanation for the image manipulations. The Editor-in-Chief of Gene has therefore lost confidence in the validity of this work and has decided to retract it. 

Retracted: Yes

PubPeer comments:
 Fig 1C,D.  SGC-7901 and MGC-803 cells were transfected with miR-361-5p mock or miR-361-5p mimic respectively. ... (C-D) Invasion ability of transfected cells were measured by transwell model. For both cell-lines, Control and miR-361-5p mock images appear to have come from the same experiment. ![file] , 
 Fig 1D again. ![file] Blue rectangle marks overlap with Fig 2E from [Jiang et al (2018)] . ![file] , 
 Fig 1C again. ![] Green rectangle marks overlap with lncRNA-MEG3 panel of Fig 2B from [Xu et al (2018)] . ![] The Control and MEG3-scramble panels of that figure also overlap with the present Fig 1D. ![] , 
 Figure 1 appears to have many image duplications - within an image and across other images. I increased the contrast a little to make this easier to see. ![file] , 
 1C again. ![] With yellow and green rectangles to help compare panels with those of Fig 2B in [Yang et al (2018)] . ![file] , 
 Retracted [17 November 2021] . ------------------------------- This article has been retracted: please see Elsevier Policy on Article Withdrawal . Several figures presented in the manuscript appear to have been doctored. Figure 1C contains copied areas between the Control group and miR-361-5p mock panels. An area from Figure 1C miR-361-5p mock panel is copied from Figure 2B lncRNA-MEG3 panel from the publication Oncology Reports 39-48, 2018 doi:10.3892 or.2018.6424 Figure 1D contains copied areas between the Control group and miR-361-5p mock panels. Figures 1E and 1F show several copied areas between one other. At higher contrast, the western blot presented in Figure 3G shows signs of picture manipulation The journal has tried to contact the authors of this article but at the time of publication of this notice has not received any explanation for the image manipulations. The Editor-in-Chief of Gene has therefore lost confidence in the validity of this work and has decided to retract it. ,