Primary sternum diffuse large B-cell lymphoma: A case report and review of the literature
Authors: Meng-Ying Tong
Xiu-Hua Sun
Xian Zhang
Zhe Yu
Shuang Li
Yang Zhang
Journal: Oncology Letters (2015)
Discipline: CLINICAL MEDICINE
Keywords: diffuse large B-cell lymphoma; primary bone lymphoma; sternum.
Affiliations: Graduate Institute of Dalian Medical University, Dalian, Liaoning 116044, P.R. China., Department of Oncology, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116027, P.R. China.

Abstract:  Primary bone lymphoma (PBL) is a rare disease, accounting for &gt;1% of all cases of malignant lymphoma. Diffuse large B-cell lymphoma (DLBCL) is the most common histological type of PBL. The present study reported the case of a 68-year-old male with primary bone DLBCL, originally occurred in the sternum, which is a rare form of presentation. Computed tomography (CT), magnetic resonance imaging and bone emission CT were performed, followed by immunohistochemical analysis of a biopsy specimen, and the results were used to establish the diagnosis. At the time of diagnosis, no osseous involvement was observed. The clinical, radiological and histological features of PBL can mimic other medical conditions, thereby making the diagnosis difficult, and frequently leading to delays in treatment. The present study investigated the clinical features, management and prognosis of PBL, and reviewed previous relevant cases. 

Retracted: No

PubPeer comments:
 Figure 4. * Red boxes: Panels I (CD5) and J (CD3) appear to show an overlap if one of the panels is rotated 180 degrees. ![file] , 
 #1 C and F also overlap although proportion and shading are different. , 
 You are completely right, Oenanthe, thank you. Figure 4 - updated. * Red boxes: Panels I (CD5) and J (CD3) appear to show an overlap if one of the panels is rotated 180 degrees. * Yellow boxes: Panels C (C79a) and F (MUM-1) appear to shown an overlap. ![file] , 
 Corrigendum. [7 January 2021] . --------------------------------------------------- The authors have re-examined their data, and realized that the same data panel was inadvertently incorporated into Fig. 4 twice, albeit in the different positions shown. To rectify this situation, and to better illustrate their findings, the authors have requested that they show all their markers in a revised version of Fig. 4, and this is presented on the next page. Furthermore, the legend for Fig. 4 has been revised to the following: u201cFigure 4. Diffuse infiltration of large B-cells. (A and B) Hematoxylin and eosin-stained cells (A, u00d7200; B, u00d7400). Immunohistochemical analysis revealed that the neoplastic cells were positive for (C) CD20, (D) CD79a, (E) BCL-6, (F) CD10, (G) MUM-1 and (H) Ki-67, partially positive for (I) EMA, weakly positive for (J) CD5, (K) CD3 and (L) BCL-2, and negative for (M) AE1 AE3, (N) CD30 and (O) ALK (u00d7400). MUM-1, multiple myeloma oncogene 1; EMA, epithelial membrane antigen; BCL, B-cell lymphoma; AE, anion exchanger; ALK, anaplastic lymphoma kinase.u201d. Finally, the text in the Results section on p. 2624, line 2, should have read as follows (changes highlighted in bold): u201cHowever, the specimen was weakly positive for CD5, CD3 and BCL-2, and negative for anaplastic lymphoma kinase, CD30 and anion exchanger (AE)1 AE3.u201d. The authors regret the error that was made in the preparation of the published figure, and confirm that this error, together with the revisions now made to the text, did not affect the diagnosis of this case. The authors are grateful to the editor of Oncology Letters for allowing them the opportunity to publish a Corrigendum, and all the authors agree to this Corrigendum. Furthermore, they apologize to the readership for any inconvenience caused. ![] , 
 Thank you for the update, Hoya. I was the  interested reader and reported this concern to the journal publisher (Spandidos) in August 2020. However, I was not notified about this correction. ,