RETRACTED: USP1 Regulates Cellular Senescence by Controlling Genomic Integrity
Authors: Jean-Marc Lemaitre
Gregory Dore
Ricardo Ivan Martinez-Zamudio
Müge Ogrunc
Helene Schwerer
Paul Ben Sadoun
Philippe Pasero
Oliver Bischof
Anne Dejean
Journal: Cell Reports (2016)
Discipline: MOLECULAR BIOLOGY & GENETICS
Keywords: Retraction; Western blots; Incorrect data; Image flipping; Irregularities
Affiliations: Institut Pasteur, Laboratory of Nuclear Organization and Oncogenesis, Department of Cell Biology and Infection, 75015 Paris, France; INSERM, U993, 75015 Paris, France; Equipe Labellisée Ligue Nationale Contre le Cancer, 14 rue Corvisart, 75013 Paris, France., Institut Pasteur, Laboratory of Nuclear Organization and Oncogenesis, Department of Cell Biology and Infection, 75015 Paris, France., Institute de Médecine Régénératrice et Biothérapies (IRMB), Université de Montpellier, CHU Montpellier, Hopital Saint-Eloi, 34295 Montpellier, France; INSERM U1183 Team "Genome and Stem Cell Plasticity in Development and Aging" Equipe Labellisée Ligue contre le Cancer, 80 rue Augustin Fliche, 34295 Montpellier, France., Institute of Human Genetics, UPR 1142, Centre National de la Recherche Scientifique (CNRS), 141 rue de la Cardonille, 34396 Montpellier, France; Equipe Labellisée Ligue Contre le Cancer, 14 rue Corvisart, 75013 Paris, France., Institut Pasteur, Laboratory of Nuclear Organization and Oncogenesis, Department of Cell Biology and Infection, 75015 Paris, France; INSERM, U993, 75015 Paris, France; Equipe Labellisée Ligue Nationale Contre le Cancer, 14 rue Corvisart, 75013 Paris, France. Electronic address: .

Abstract:  This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the authors. We, the authors, were made aware of irregularities associated in western blots shown in our article. We have further investigated the matter and found that the paper contains multiple examples of incorrect data use and image flipping in four figures, including the vertical flipping and reuse of the panel in Figures 1B and 3D, similar flipping and incorrect blot image in Figure 2C, and incorrect data use in Figure 4A. All of these figures were assembled by the corresponding author (O.B.) who takes full responsibility for the inaccuracies. Under these circumstances, we believe that the most responsible course of action is to retract the paper. We sincerely apologize to the scientific community for any inconvenience resulting from the publication and retraction of this manuscript. 

Retracted: Yes

PubPeer comments:
 Figures 1B and 3C. Much more similar than you would expect. ![file] , 
 Retracted February 23, 2021 (Cell Reports 15, 108786-1401u2013108786-1411; May 17, 2016) We, the authors, were made aware of irregularities associated in western blots shown in our article. We have further investigated the matter and found that the paper contains multiple examples of incorrect data use and image flipping in four figures, including the vertical flipping and reuse of the panel in Figures 1B and 3D, similar flipping and incorrect blot image in Figure 2C, and incorrect data use in Figure 4A. All of these figures were assembled by the corresponding author (O.B.) who takes full responsibility for the inaccuracies. Under these circumstances, we believe that the most responsible course of action is to retract the paper. We sincerely apologize to the scientific community for any inconvenience resulting from the publication and retraction of this manuscript. , 
 2021 retraction. RETRACTION| VOLUME 34, ISSUE 8, 108786, FEBRUARY 23, 2021 Retraction notice to: USP1 regulates cellular senescence by controlling genomic integrity Mu00fcge Ogrunc Ricardo Ivan Martinez-Zamudio Paul Ben Sadoun Jean-Marc Lemaitre Anne Dejean Oliver Bischof Show all authors Open AccessDOI:https: doi.org 10.1016 j.celrep.2021.108786 (Cell Reports 15, 108786-1401u2013108786-1411; May 17, 2016) We, the authors, were made aware of irregularities associated in western blots shown in our article. We have further investigated the matter and found that the paper contains multiple examples of incorrect data use and image flipping in four figures, including the vertical flipping and reuse of the panel in Figures 1B and 3D, similar flipping and incorrect blot image in Figure 2C, and incorrect data use in Figure 4A. All of these figures were assembled by the corresponding author (O.B.) who takes full responsibility for the inaccuracies. Under these circumstances, we believe that the most responsible course of action is to retract the paper. We sincerely apologize to the scientific community for any inconvenience resulting from the publication and retraction of this manuscript. There are already 3 retractions for Oliver Bischof in the Retraction Watch database. http: retractiondatabase.org RetractionSearch.aspx?#?auth%3dOliver%2bBischof ,