Philic‚Äìphobic chemical dynamics of a 1st tier dendrimer dispersed o/w nanoemulsion
Authors: K M Sachin
Naveen Kumari
Man Singh
Hari Om
Journal: RSC Advances (2019)
Discipline: CHEMISTRY
Keywords: nanoemulsions; dispersion effect; surfactant; co-surfactant; physicochemical properties
Affiliations: Department of Chemistry, Deenbandhu Chhotu Ram University of Science and Technology, India, School of Chemical Sciences, Central University of Gujarat, Gandhinagar

Abstract:  Olive, castor and linseed oil (oil-in-water) nanoemulsions were prepared using Tween-20, sodium dodecyl sulfate, and cetyltrimethylammonium bromide (0.12 w/w%) with 0.02 w/w% cellulose acetate propionate (CAP), 0.02 w/w% cellulose acetate butyrate (CAB), 6.2 w/w% ethyl acetate, 5.5 w/w% ethanol and 7.8 w/w% glycerol as dispersion agents. To study the dispersion effect of trimesoyl 1,3,5-tridimethyl malonate (TTDMM, 1st tier), nanoemulsions were prepared with olive, castor and linseed oil. Their density, viscosity, surface tension and friccohesity measurements at T = (293.15, 303.15, and 315.15) K, hydrodynamic radii, surface excess concentration, surface area per molecule, and antioxidant activities were studied. Dispersion variations of TTDMM on varying surfactant and specific interactions of the hydration spheres and ester moiety of TTDMM with ethyl acetate, ethanol and glycerol linked oil-water-surfactant networks have been established. The variations in physicochemical properties suggest that the oil-TTDMM interaction abilities of the surfactant and co-surfactant moieties in the nanoemulsions cause a hydrophobic segregation. The physicochemical study of both blank and TTDMM loaded nanoemulsions have illustrated the thermodynamic stabilities in terms of hydrophobic-hydrophilic, hydrophilic-hydrophilic, van der Waals and hydrogen bonding interactions. 

Retracted: No

PubPeer comments:
 Fig 2(b).  FOSL1, Cu2010JUN, Cu2010FOS, APu20101, pu2010ERK1 2, and pu2010p38MAPK protein expression was increased in OS .  The protein blobs seem to come from the same restricted gamut shown in this montage.  , 
 Figs 4(b,e) and 5(b,e).  I am intrigued by the absence of background on these WBs, and the way the bands remain perfectly linear and retain the shape of the protein blobs as they move up the gel. Is it possible for the authors to upload the original scans of the gels? Numerous other papers have Figures which display the same qualities, hence my curiosity. I compiled a montage:  , 
 Fig 9(a,c).  FOSL1 silencing exerts a negative effect on OS cell invasion (u00d7200). (a,b) Transwell assay results suggested that in Saos2 cell line, OS cell invasion was inhibited by FOSL1 depletion. (c,d) Transwell assay exhibited that in MG63 cell line, OS invasion was inhibited by FOSL1 depletion .  Panels appear, differently labeled, in Fig 9C of [Wen et al (2017)] .  Effects of siR-SPRY4-IT1 expression on the invasion and metastasis abilities of A549 and H1975 cells ... C, the Transwell assay detection of the invasion ability of H1975 cells in the four groups evaluated by Transwell assay .  , 
 Retracted [30 June 2021] . ------------------------------- The above article, published online on 23 November 2018 in Wiley Online Library has been retracted by agreement between the authors, the journal s Editor in Chief, Prof. Dr. Gregg Fields, and Wiley Periodicals LLC. The retraction has been agreed following an investigation based on allegations raised by a third party. A detailed investigation revealed that several image elements of the experimental data were published elsewhere in a different scientific contest. Additionally, the authors asked to retract their paper due to anomalies in the Transwell data. Thus, the conclusions of the article are considered to be invalid. ,