Cu(II)-Containing Metal‚ÄìOrganic Framework with 1D Hexagonal Channels for Cyanosilylation Reaction and Anticancer Activity on Osteosarcoma Cells
Authors: Ze Zhou
Lv-Fang Ying
Yan-Guo Zhang
Feng Zhang
Jian Luo
Journal: ACS Omega (2021)
Discipline: CHEMISTRY
Keywords: metal-organic framework; Cu(NO3)2¬∑6H2O; 3-(1H-tetrazol-5-yl)pyridine; water; chemical formula
Affiliations: Department of Orthopaedics, Ningbo Hangzhou Bay Hospital, Ningbo, Zhejiang 315336, China, Department of Neurosurgery, Qiqihar Medical University, Qiqihar, Heilongjiang 161006, China

Abstract:  A novel metal-organic framework (MOF) has been produced via Cu(NO3)2¬∑6H2O reaction with 3-(1H-tetrazol-5-yl)pyridine (HL) in water, and its chemical formula is {[(Cu(L)2(H2O)2](H2O)8) n } (1). Due to its high density of coordinately unsaturated sites along with large one-dimensional (1D) hexagonal channels, the activated complex 1 (1a) was explored as the solvent-free heterogeneous catalyst for cyanosilylation under mind conditions. The inhibitory function of compound 1a against the survival rate of OS-732 osteosarcoma cells was evaluated via Cell Counting Kit-8 (CCK-8) detection kit. Furthermore, the Annexin V-FITC/PI detection kit and the active oxygen (ROS) detection kit was carried out to determine the cell apoptosis levels and the ROS accumulation in OS-732 osteosarcoma cells after treatment by compound 1a. 

Retracted: Yes

PubPeer comments:
  This **preformation** was finished totally in accordance with the protocolsu2019 guidance with minor modification. In short, the OS732 cells in the logarithmic growth phase were collected and then planted into six-well plates at 1 u00d7 10^5 cells well **ultimate destiny**. After incubation at 5% CO2 and 37 u00b0C conditions overnight, the cells were then treated with 1a for 24 h. These curious terms are often found in [the products of a prolific papermill] .  , 
 The papermill in question is also fond of recycling a small repertoire of weirdly irrelevant References. Here the authors are under the impression that Ref [22] is about a copper-based Metal-Oxide Framework.  The lengths of the Cuu2212N bond span from 2.018(4) and 2.036(4) u00c5, and the Cuu2212O bond length is 2.426 u00c5; on the basis of several nitrogen-donor ligands, these values are all in the normal range of the Cuu2212N and Cuu2212O bond distances in other Cu(II)-based MOFs.22u221224 - (22) Duan, C.; Su, Z.; Cao, Y.; Hu, L.; Fu, D.; Ma, J.; Zhang, Y. Synthesis of core-shell u03b1-AlH3@Al(OH)3 nanocomposite with improved low-temperature dehydriding properties by mechanochemical mixing and ionic liquid treatment. J. Cleaner Prod. 2021, 283, No. 124635. The mill s products are often of a  Floor-wax-AND-a-dessert-topping nature. Here, the dessert topping is that the material also possesses  1D Hexagonal Channels for Cyanosilylation Reaction . , 
 Is this a misspelling of [u201clogarithmic growth phaseu201d] ?  Found with the [_Problematic Paper Screener_] . , 
 According to Table 3, the crystal-structure determination data and parameters for the present compound are in the CCDC database with Deposition Number 1971058. The CCDC database informs me that the dataset was deposited by [Meng Qinghua, of Hang Zhou University] . By my reckoning, [Meng Qinghua has deposited 118 crystal structures with CCDC] . Most of them became parts of problematic papers by otherwise-unrelated teams of authors, including this one. , 
 [Retraction] , dated March 1, 2022. The Editors retract this article because concerns regarding the integrity of the work were identified, and the authors were unable to provide the raw data for the cell viability assays and the GC and NMR analyses to resolve the matter. --- This **conduction** was completed under the guidance of the instructions. Sometimes  conduction alternates with [ preformation ] as a strange replacement for  protocol  procedure in the artifacts produced by this presumed papermill. ,