RETRACTED: Downregulation of lncRNA GAS5 confers tamoxifen resistance by activating miR-222 in breast cancer
Authors: Juan Gu
Ming Zhou
Xuedong Wang
Daoping Zhou
Zhimin He
Chaopeng Shao
Yueping Wang
Journal: Cancer Letters (2018)
Discipline: CLINICAL MEDICINE
Keywords: Breast cancer; Drug resistance; LncRNA GAS5; MiR-222; Tamoxifen.
Affiliations: Department of Medical Laboratory Science, The Fifth People's Hospital of Wuxi, The Medical School of Jiangnan University Wuxi, Jiangsu, 214000, PR China; Department of Pathology, The Fifth People's Hospital of Wuxi, Nanjing Medical University, Wuxi, Jiangsu, 214000, PR China., Department of Medical Laboratory Science, The Fifth People's Hospital of Wuxi, The Medical School of Jiangnan University Wuxi, Jiangsu, 214000, PR China; Department of Biology, College of Arts & Science, Massachusetts University, Boston, MA, 02125, USA; Department of Oncology, The Second People's Hospital of Anhui Province, Anhui Medical University, Hefei, Anhui, 230041, PR China., Department of Medical Laboratory Science, The Fifth People's Hospital of Wuxi, The Medical School of Jiangnan University Wuxi, Jiangsu, 214000, PR China; Department of Pathology, The Fifth People's Hospital of Wuxi, Nanjing Medical University, Wuxi, Jiangsu, 214000, PR China; Department of Oncology, The Second People's Hospital of Anhui Province, Anhui Medical University, Hefei, Anhui, 230041, PR China. Electronic address: ., Department of Oncology, The Second People's Hospital of Anhui Province, Anhui Medical University, Hefei, Anhui, 230041, PR China., Department of Blood Transfusion, The Second People's Hospital of Shenzhen, Shenzhen, 518035, Guangdong, PR China., Cancer Research Institute, Central South University, Changsha, Hunan, 410078, PR China., Cancer Hospital and Cancer Research Institute, Guangzhou Medical University, Guangzhou, Guangdong, 510095, PR China.

Abstract:  This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief. Upon investigation, it was discovered that 5 figures contain fabrication. Figures 1C, 3D, 5C, 5D, and 6G contain manipulated and/or duplicated data. The authors requested a corrigendum be published, however, due to the large number of corrections applied (figures 3, 6, 7, 8 and S3), it cannot be concluded that these changes would not alter the conclusions of the paper. The scientific community takes a very strong view on this matter and apologies are offered to readers of the journal that this was not detected during the submission process. 

Retracted: Yes

PubPeer comments:
null, 
 https: www.buzzfeednews.com article peteraldhous a-uk-university-knew-of-problems-in-a-top-geneticists-lab  But when Anastasis Stephanou, who led a research group at University College London studying the biology of heart disease, was asked for the data behind a 2006 paper whose results were being called into question, he was unable to provide it. The incident, described in a 2007 email obtained by BuzzFeed News, shows that some UCL officials were aware of concerns about data fraud in research overseen by leading geneticist David Latchman, in whose lab Stephanou worked, more than a decade before launching a formal investigation. The hyperlink from  2006 paper is https: www.ncbi.nlm.nih.gov pubmed 16697404 That is this paper. , 
 See https: www.buzzfeednews.com article peteraldhous a-uk-university-knew-of-problems-in-a-top-geneticists-lab (published on 25 January 2020). , 
 Figure 5B. Much more similar than you would expect. https: imgur.com 0aS0O0l ,