Highly monodisperse Pd-Ni nanoparticles supported on rGO as a rapid, sensitive, reusable and selective enzyme-free glucose sensor
Authors: Kemal Cellat
Elif ≈ûahin I≈ügƒ±n
Servet Kƒ±zƒ±ldaƒü
Senem Karahan G√ºlbay
Kubilay Arƒ±kan
Fatih Tezcan
Fatih ≈ûen
Aysun ≈ûavk
Journal: Scientific Reports (2019)
Discipline: Multidisciplinary
Keywords: Palladium-nickel nanoparticles; reduced graphene oxide; glucose detection; electrochemical impedance spectroscopy; chronoamperometry
Affiliations: Sen Research Group, Biochemistry Department, Faculty of Arts and Science, Dumlupƒ±nar University, Evliya √áelebi Campus, 43100, K√ºtahya, Turkey., Mersin University, Science and Letters Faculty, Chemistry Department, 33343, Mersin, Turkey., Department of Chemistry, Faculty of Sciences, Dokuz Eylul University, Buca, ƒ∞zmir, Turkey., College of Vocational School of Health Services, Dokuz Eyl√ºl University School of Medicine, ƒ∞zmir, Turkey., Department of Chemistry, Faculty of Sciences, Dokuz Eylul University, Buca, ƒ∞zmir, Turkey. ., Sen Research Group, Biochemistry Department, Faculty of Arts and Science, Dumlupƒ±nar University, Evliya √áelebi Campus, 43100, K√ºtahya, Turkey. .

Abstract:  In this work, highly monodispersed palladium-nickel (Pd-Ni) nanoparticles supported on reduced graphene oxide (rGO) were synthesized by the microwave-assisted methodology. The synthesized nanoparticles were used for modification of a glassy carbon electrode (GCE) to produce our final product as PdNi@rGO/GCE, which were utilized for non-enzymatic detecting of glucose. In the present study, electrochemical impedance spectroscopy (EIS), chronoamperometry (CA) and, cyclic voltammetry (CV) methods were implemented to investigate the sensing performance of the developed glucose electrode. The modified electrode, PdNi@rGO/GCE, exhibited very noticeable results with a linear working range of 0.05-1.1 mM. Moreover, an ultralow detection limit of 0.15 ŒºM was achieved. According to the results of amperometric signals of the electrodes, no significant change was observed, even after 250 h of operation period. In addition, the highly monodisperse PdNi@rGO/GCE was utilized to electrochemical detection of glucose in real serum samples. In light of the results, PdNi@rGO/GCE has shown an excellent sensing performance and can be used successfully in serum samples for glucose detection and it is suitable for practical and clinical applications. 

Retracted: No

PubPeer comments:
 Two identical XRD patterns different only by label (Ni added)  , 
 Unexpected similarity in TEM image of nanoparticle (only zoomed part) with another paper https: pubpeer.com publications FE82B8B82046CD18BE848962888773 Histograms from these two papers also very similar  , 
 To add to Thallarcha Lechrioleuca s finding in comment #2, this paper is one of at least 30 papers by the same research group that all share the same photo. In all papers, this photo is used as a zoomed-in inset representing the high-resolution transmission electron microscopy (HRTEM) analysis of the  atomic lattice fringe and particle size of the nanoparticles. Of concern, the same photo is used to represent a different type of nanoparticle in each of these papers. Here is a collage of 6 different uses of the same photo,  Inset 1 :  Here is a list of the 30 papers identified so far that all use this photo, and the different types of nanoparticles that they represent. * Aysenur Aygun et al. - DOI: 10.1016 j.jpba.2019.112961 - Nigella sativa Pt * Aysun Su0327avk et al. - DOI: 10.1016 j.molliq.2019.112355 - PtNi@AC * Aysun Su0327avk et al. - DOI: 10.1016 j.msec.2019.01.113 - ZnNi@f-MWCNT * Aysun Su0327avk et al. - DOI: 10.1038 s41598-019-55746-y - PdNi@rGO * Betuu0308l Su0327en et al. - DOI: 10.1016 j.ijhydene.2018.03.175 - Pd@GO * Betuu0308l Su0327en et al. - DOI: 10.1016 j.nanoso.2017.08.013 - PdRu@GO * Betuu0308l Su0327en et al. - DOI: 10.1016 j.apcatb.2017.11.067 - RhPt TC@GO * Betuu0308l Su0327en et al. - DOI: 10.1016 j.ijhydene.2018.07.081 - Pd-Ir@AC * Betuu0308l Su0327en et al. - DOI: 10.1016 j.jcis.2018.05.021 - Ru-Ni@PVP * Betuu0308l Su0327en et al. - DOI: 10.1016 j.nanoso.2018.07.008 - Pd@AC * Betuu0308l Su0327en et al. - DOI: 10.1016 j.ijhydene.2018.07.122 - PdRuNi@GO * Betuu0308l Su0327en et al. - DOI: 10.1016 j.ijhydene.2019.01.215 - PdCo@GO * Betuu0308l Su0327en et al. - DOI: 10.1016 j.jtice.2019.04.040 - PdNi@VC * Betuu0308l Su0327en et al. - DOI: 10.1016 j.ijhydene.2018.12.051 - PdCo@MOF * Betuu0308l Su0327en et al. - DOI: 10.1016 j.ijhydene.2019.02.176 - RuCu@rGO * Birguu0308tay Su0327ahin et al. - DOI: 10.1016 j.colsurfb.2017.12.042 - Pt * Buse Demirkan et al. - DOI: 10.1038 s41598-020-59935-y - rGO Pd@PPy * Buse Demirkan et al. - DOI: 10.1038 s41598-019-48802-0 - Pt-Co@rGO * Fatma Diler et al. - DOI: 10.1016 j.molliq.2019.111967 - Pd@GO * Hayriye Genc Bilgicli et al. - DOI: 10.1016 j.micromeso.2020.110014 - CPG * Hilal Acidereli et al. - DOI: 10.1016 j.renene.2020.07.105 - PdRu@G * Mehmet Salih Nas et al. - DOI: 10.1016 j.molliq.2019.112100 - Pt-Co@GO * Nabih Lolak et al. - DOI: 10.1021 acsomega.9b00485 - PdNi@GO * Oznur Alptekin et al. - DOI: 10.1039 D0CY00641F - PtRh@GO * Rukiye Ayranci et al. - DOI: 10.1016 j.msec.2019.02.040 - Pt Ni@rGO * Sait Bozkurt et al. - DOI: 10.1016 j.aca.2017.07.051 - Pd TNM@rGO * Sinan Eris et al. - DOI: 10.1016 j.jcis.2017.11.085 - Pt@f-CB * Sinan Eris et al. - DOI: 10.1016 j.ijhydene.2017.11.063 - Pt@f-VC * Suat Tacu0327yu0131ldu0131z et al. - DOI: 10.1016 j.molliq.2019.04.019 - Ru-Rh@PVP * Zeynep Dasu0327delen et al. - DOI: 10.1016 j.apcatb.2017.08.014 - Pt@GO-PVP , 
 XPS Pd 3d spectrum is found also in RSC Advances 2016 paper representing there PdRuNi@GO. https: pubpeer.com publications 333B326822135A21713764E73A2B86#4 It is also found in one more paper (3D figure) from 2017 (Betu00fcl u015een et al, Nano-Structures Nano-Objects 12 (2017) 33u201340): https: pubpeer.com publications 7A123B2F1443D6AC355E4B633E05E2#3  Ru is gone and GO is reduced in 2019 study but Pd 3d spectrum keeps the same noise. , 
 One more copy of this XPS spectrum (current count is 4 appearances) is here: https: pubpeer.com publications F37615D2B93BBAAB41C4DCA099D5CD#3  ,