A mixed-ligand Zn(II)-coordination polymer: selective detection of Fe3+ ion and promotion activity on the flap transplantation via increasing the vascular endothelial cells proliferation
Authors: Yao, Bin
Wei, Yuan
Li, Ceng
Wei, Cheng
Wang, Rong
Journal: Journal of the Iranian Chemical Society (2021)
Discipline: CHEMISTRY
Keywords: tripodal connector; Zn(II)-coordination polymer; luminescent; Fe3+ ion; sensing performances

Abstract: In the current study, on the basis of 1,3,5-tris(2-methylimidazol-1-yl)benzene (timb), a designed tripodal connector, a novel two-dimensional luminescent Zn(II)-coordination polymer whose chemical formula is {[Zn5(timb)4(OH‚ÄìIPA)4]¬∑2NO3¬∑2DMA¬∑2H2O}n was generated through the reaction between timb and Zn(NO3)2¬∑6H2O in the presence of the OH functionalized isophthalic acid ligand (OH-H2IPA). Furthermore, for the Fe3+ ion, complex 1 reflects superb luminescence sensing performances in the water solution with high selectivity and high sensitivity. The assessment of its promotion activity on the flap transplantation was implemented. Meanwhile, its detailed mechanism was also studied. First of all, the detection of the proliferation activity levels on vascular endothelial cells was conducted with the Cell Counting Kit-8. Subsequently, the signaling pathway of HIPPO activation level was further detected in the vascular endothelial cells after compound treatment.

Retracted: No

PubPeer comments:
 The relevance of the  flap transplantation part of the title is that the authors claim to have cultivated vascular endothelial cells (without specifying a source for the  harvesting , or a growth medium) and to have accelerated their proliferation using the present material in some unspecified manner.  In a word, in logical growth phage, vascular endothelial cell could be harvested and then the cell was implanted into 96 well plates, with 10^6 cells in each well. These cells were cultured into a 5%CO2 and 37 u00b0C incubator. Afterward, we added the compound into the well for the treatment of 10 u03bcg mL, 20 u03bcg mL and 50 u03bcg mL concentration.  In a word, vascular endothelial cell in the **logical growth phage** were harvested and implanted into 6 well plates, with 10^6 cells in each well. This curious term  logical growth phage seems to be [one of the hallmarks of a papermill] .  , 
 Is there any reason why corresponding author Rong Wang uses the email identity  sanghaiquan0725@163.com for correspondence? Is Sang Haiquan aware of this borrowed identity? , 
 A number of these papers use a strip of  References Wallpaper to construct their References section, without seeking to harmonise it with the in-text citations. These are **not about coordination polymers**.  As an organicu2013inorganic hybrid crystal material, coordination polymers (CPs) have caused increasing attention from material scientists and chemists owing to their structural diversities and potential applications as the functional materials in molecular detection and sensing, chemical separation and adsorption, fuel cells, proton conduction, and photocatalysis and catalysis of the organic reactions, etc. [4u20136]. - [4]. D. Yuan, M. Sun, M. Zhao, S. Tang, J. Qi, X. Zhang, K. Wang, B. Li, Int. J. Electrochem. Sci. 15, 8761u20138770 (2020) ** Persulfate Promoted ZnIn2S4 Visible Light Photocatalytic Dye Decomposition ** - [5]. N. Jiang, Y. Liu, X.N. Yu, H.B. Zhang, M.M. Wang, Int. J. Electrochem. Sci. 15, 5520u20135528 (2020) ** Corrosion Resistance of Nickel-Phosphorus Nano-ZnO Composite Multilayer Coating Electrodeposited on Carbon Steel in Acidic Chloride Environments **  Organic connectors, as the backbone of the skeletons, as the active sites for the functionalization of confned spaces, and coordination groups that interact with secondary building units (SBU), metal ions, and even the metal clusters, have a great impact on their performances [7u20139] - [9]. C. Duan, Z. Su, Y. Cao, L. Hu, D. Fu, J. Ma, Y. Zhang, J. Clean. Prod. 283, 124635 (2021) ** Synthesis of core-shell u03b1-AlH3@Al(OH)3 nanocomposite with improved low-temperature dehydriding properties by mechanochemical mixing and ionic liquid treatment ** ,