A Bifunctional Metal‚ÄìOrganic Framework Based on Linear Trinuclear Clusters for Solvent-Free Aldehyde Cyanosilylation and Growth Inhibition of Human Breast Cancer Cells
Authors: Ma, Zhi-Jun
Lu, Shih-Hsin
Journal: Journal of Cluster Science (2019)
Discipline: CHEMISTRY
Keywords: Metal-organic framework; Cluster-based; Biphenyl-3,4‚Ä?5-tricarboxylic acid; Solvothermal synthesis; Single-crystal X-ray diffraction

Abstract: By using a rigid Y-shaped biphenyl-3,4‚Ä?5-tricarboxylic acid (H3bpt) organic ligand, a new cluster-based metal-organic framework (MOF) with the chemical formula of {[Cu3(bpt)2(H2O)4](DMA)(MeOH)2}n (1, DMA = N,N-dimethylacetamide) was synthesized under solvothermal condition. The structure of 1 was determined by single-crystal X-ray diffraction analyses (SCXRD) and further characterized by elemental analyses, IR spectroscopy, powder X-ray diffraction (PXRD), thermogravimetric (TG) analyses and gas sorption measurements. The SCXRD result reveals that complex 1 exhibits a 3D framework with 1D channels which contains opposite-handedness helical chains based on the trinuclear Cu(II) clusters. Considering its high pore volume and accessible open metal sites, complex 1 as well as its activated form (1a) was studied for cyanosilylation of aldehydes under solvent-free conditions, which reveals that 1a shows much better catalytic performance than that of 1, indicating the open metal sites play important roles in the catalytic process. Furthermore, the anticancer activates of complex 1 and 1a has been evaluated on three human breast cancer cells (MDA-MB-231, MDA-MB-468 and Hst578) via the MTT assay.

Retracted: No

PubPeer comments:
 Could the authors check that the materials described in [11] and [12] are MOFs?  MOFs have received a great deal of attention in recent years as the result of their diverse architectures and for their many potential applications in gas storage and separation, ion exchange, luminescence and so on [11u201314]. - [11]. Y. Feng, H. Fan, Z. Zhong, H. Wang, and D. Qiu (2016). Inorg. Chem. 55, 11987. ** Cd3(MoO4)(TeO3)2: A Polar 3D Compound Containing d10u2013d0 SCALP-Effect Cations ** - [12]. Y. Feng, M. Li, H. Fan, Q. Huang, D. Qiu, and H. Shi (2015). Dalton Trans. 44, 894. ** A novel open-framework copper borophosphate containing 1-D borophosphate anion with 10-MR windows and 12-MR channels ** Could the authors check the relevance of [15] to MOF assembly?  Generally, in the self-assembly reaction of metal and ligand, the choice of the appropriate ligand is crucial and predetermines most structures and properties related to the final products [15]. - [15]. C. W. Duan, L. X. Hu, and J. L. Ma (2018). J. Mater. Chem. A 6, 6309. ** Ionic liquids as an efficient medium for the mechanochemical synthesis of u03b1-AlH3 nano-composites ** , 
 This is one of a large number of coordination-chemistry papers that appear to have all been written according to a template. - Most draw on two papers by Y. Feng et al. and one by C.-W. Duan et al to illustrate the broad range of applications and properties of MOFs. Notably, these are not papers about MOFs. - - Y. Feng, H. Fan, Z. Zhong, H. Wang, D. Qiu, Inorg. Chem. 2016, 55, 11987u201311992.  Cd3(MoO4)(TeO3)2: A Polar 3D Compound Containing d10-d0 SCALP-Effect Cations - - Y. Feng, M. Li, H. Fan, Q. Huang, D. Qiu, H. Shi, Dalton Trans. 2015, 44, 894u2013897.  A Novel Open-Framework Copper Borophosphate Containing 1-D Borophosphate Anion with 10-MR Windows and 12-MR Channels - - C. W. Duan, L. X. Hu, J. L. Ma, J. Mater. Chem. A 2018, 6, 6309u20136318  Ionic liquids as an efficient medium for the mechanochemical synthesis of u03b1-AlH3 nano-composites - The cluster is sometimes accompanied by less relevant references and clusters of references. Frequently co-occuring papers include - - Duan CW, Cao YZ, Hu LX, Fu D, Ma JL (2019)  Synergistic effect of TiF3 on the dehydriding property of a-AlH3 nano-composite . - - K. Wang, J. Pang, L. Li, S. Zhou, Y. Li, T. Zhang, Front. Chem. Sci. Eng. 2018, 12, 376u2013382.  Synthesis of hydrophobic carbon nanotubes reduced graphene oxide composite films by flash light irradiation - - K. Wu, K. Du, G. Hu, J. Mater. Chem. A 2018, 6, 1057u20131066  Red-blood-cell-like (NH4) [Fe2(OH)(PO4)2]u00b72H2O particles: Fabrication and application in high-performance LiFePO4 cathode materials - - Yin K, Chu DK, Dong XR, Wang C, Duan JA, He J (2017)  Femtosecond laser induced robust periodic nanoripples structured mesh for highly efficient oil-water separation . Nanoscale 9:14229u201314235. - - Davila-Manzanilla SG, Figueroa-de-Paz Y, Mejia C, Ruiz-Azuara L (2017)  Synergistic effects between a copper-based metal Casiopeu00edna III-Ia and cisplatin . Eur J Med Chem 129:266u2013274 - The vast majority of email identities for corresponding authors were formed by taking an underscore-separated name and appending **666** or 66 . I am advised that these are auspicious numbers with positive associations. So one possibility is that the authors all decided independently to generate email accounts with this format. The alternative is that *some outside contractor* handled the task of negotiating with journals (generating these disposable accounts in the process) - perhaps also the task of writing the manuscripts, using a single Bibliography file to save time. The complete list [is here] . , 
  CCDC No. 1881076 contains the supplementary crystallographic data for this paper. The CCDC database informs me that the dataset was deposited by [Meng Qinghua, of Hang Zhou University] . By my reckoning, [Meng Qinghua has deposited 118 crystal structures with CCDC] . Most of them became parts of problematic papers by otherwise-unrelated teams of authors, including this one. ,