Question: Cortisol interacts with what protein?
Paraphrase: Cortisol interatomic with what protein?
SPARQL (Wikidata):  select distinct ?obj where { wd:Q190875 wdt:P129 ?obj . ?obj wdt:P31 wd:Q8054 } 
Answer: Nuclear receptor subfamily 3 group C member 1, Nuclear receptor subfamily 3 group C member 2