OpenRaiser/Intern-Atlas huggingface dataset:
Rethinking Graph Super-resolution: Dual Frameworks for Topological Fidelity
Venue: arXiv cs.LG 2025
Year: 2025

Graph super-resolution, the task of inferring high-resolution (HR) graphs from low-resolution (LR) counterparts, is an underexplored yet crucial research direction that circumvents the need for costly data acquisition. This makes it especially desirable for resource-constrained fields such as the medical domain. While recent GNN-based approaches show promise, they suffer from two key limitations: (1) matrix-based node super-resolution that disregards graph structure and lacks permutation invariance; and (2) reliance on node representations to infer edge weights, which limits scalability and expressivity. In this work, we propose two GNN-agnostic frameworks to address these issues. First, Bi-SR introduces a bipartite graph connecting LR and HR nodes to enable structure-aware node super-resolution that preserves topology and permutation invariance. Second, DEFEND learns edge representations by mapping HR edges to nodes of a dual graph, allowing edge inference via standard node-based GNNs. We evaluate both frameworks on a real-world brain connectome dataset, where they achieve state-of-the-art performance across seven topological measures. To support generalization, we introduce twelve new simulated datasets that capture diverse topologies and LR-HR relationships. These enable comprehensive benchmarking of graph super-resolution methods.
EEG-X: Device-Agnostic and Noise-Robust Foundation Model for EEG
Venue: arXiv cs.LG 2025
Year: 2025

Foundation models for EEG analysis are still in their infancy, limited by two key challenges: (1) variability across datasets caused by differences in recording devices and configurations, and (2) the low signal-to-noise ratio (SNR) of EEG, where brain signals are often buried under artifacts and non-brain sources. To address these challenges, we present EEG-X, a device-agnostic and noise-robust foundation model for EEG representation learning. EEG-X introduces a novel location-based channel embedding that encodes spatial information and improves generalization across domains and tasks by allowing the model to handle varying channel numbers, combinations, and recording lengths. To enhance robustness against noise, EEG-X employs a noise-aware masking and reconstruction strategy in both raw and latent spaces. Unlike previous models that mask and reconstruct raw noisy EEG signals, EEG-X is trained to reconstruct denoised signals obtained through an artifact removal process, ensuring that the learned representations focus on neural activity rather than noise. To further enhance reconstruction-based pretraining, EEG-X introduces a dictionary-inspired convolutional transformation (DiCT) layer that projects signals into a structured feature space before computing reconstruction (MSE) loss, reducing noise sensitivity and capturing frequency- and shape-aware similarities. Experiments on datasets collected from diverse devices show that EEG-X outperforms state-of-the-art methods across multiple downstream EEG tasks and excels in cross-domain settings where pre-trained and downstream datasets differ in electrode layouts. The models and code are available at: https://github.com/Emotiv/EEG-X
SasMamba: A Lightweight Structure-Aware Stride State Space Model for 3D Human Pose Estimation
Venue: arXiv cs.CV 2025
Year: 2025

Recently, the Mamba architecture based on State Space Models (SSMs) has gained attention in 3D human pose estimation due to its linear complexity and strong global modeling capability. However, existing SSM-based methods typically apply manually designed scan operations to flatten detected 2D pose sequences into purely temporal sequences, either locally or globally. This approach disrupts the inherent spatial structure of human poses and entangles spatial and temporal features, making it difficult to capture complex pose dependencies. To address these limitations, we propose the Skeleton Structure-Aware Stride SSM (SAS-SSM), which first employs a structure-aware spatiotemporal convolution to dynamically capture essential local interactions between joints, and then applies a stride-based scan strategy to construct multi-scale global structural representations. This enables flexible modeling of both local and global pose information while maintaining linear computational complexity. Built upon SAS-SSM, our model SasMamba achieves competitive 3D pose estimation performance with significantly fewer parameters compared to existing hybrid models. The source code is available at https://hucui2022.github.io/sasmamba_proj/.
Classifying Histopathologic Glioblastoma Sub-regions with EfficientNet
Venue: arXiv cs.CV 2025
Year: 2025

Glioblastoma (GBM) is the most common aggressive, fast-growing brain tumor, with a grim prognosis. Despite clinical diagnostic advancements, there have not been any substantial improvements to patient prognosis. Histopathological assessment of excised tumors is the first line of clinical diagnostic routine. We hypothesize that automated, robust, and accurate identification of distinct histological sub-regions within GBM could contribute to morphologically understanding this disease at scale. In this study, we designed a four-step deep learning approach to classify six (6) histopathological regions and quantitatively evaluated it on the BraTS-Path 2024 challenge dataset, which includes digitized Hematoxylin \& Eosin (H\&E) stained GBM tissue sections annotated for six distinct regions. We used the challenge's publicly available training dataset to develop and evaluate the effectiveness of several variants of EfficientNet architectures (i.e., B0, B1, B2, B3, B4). EfficientNet-B1 and EfficientNet-B4 achieved the best performance, achieving an F1 score of 0.98 in a 5-fold cross-validation configuration using the BraTS-Path training set. The quantitative performance evaluation of our proposed approach with EfficientNet-B1 on the BraTS-Path hold-out validation data and the final hidden testing data yielded F1 scores of 0.546 and 0.517, respectively, for the associated 6-class classification task. The difference in the performance on training, validation, and testing data highlights the challenge of developing models that generalize well to new data, which is crucial for clinical applications. The source code of the proposed approach can be found at the GitHub repository of Indiana University Division of Computational Pathology: https://github.com/IUCompPath/brats-path-2024-enet.
Negative Entity Suppression for Zero-Shot Captioning with Synthetic Images
Venue: arXiv cs.CV 2025
Year: 2025

Text-only training provides an attractive approach to address data scarcity challenges in zero-shot image captioning (ZIC), avoiding the expense of collecting paired image-text annotations. However, although these approaches perform well within training domains, they suffer from poor cross-domain generalization, often producing hallucinated content when encountering novel visual environments. Retrieval-based methods attempt to mitigate this limitation by leveraging external knowledge, but they can paradoxically exacerbate hallucination when retrieved captions contain entities irrelevant to the inputs. We introduce the concept of negative entities--objects that appear in generated caption but are absent from the input--and propose Negative Entity Suppression (NES) to tackle this challenge. NES seamlessly integrates three stages: (1) it employs synthetic images to ensure consistent image-to-text retrieval across both training and inference; (2) it filters negative entities from retrieved content to enhance accuracy; and (3) it applies attention-level suppression using identified negative entities to further minimize the impact of hallucination-prone features. Evaluation across multiple benchmarks demonstrates that NES maintains competitive in-domain performance while improving cross-domain transfer and reducing hallucination rates, achieving new state-of-the-art results in ZIC. Our code is available at https://github.com/nidongpinyinme/NESCap.
SPEED-Q: Staged Processing with Enhanced Distillation towards Efficient Low-bit On-device VLM Quantization
Venue: arXiv cs.CV 2025
Year: 2025

Deploying Vision-Language Models (VLMs) on edge devices (e.g., smartphones and robots) is crucial for enabling low-latency and privacy-preserving intelligent applications. Given the resource constraints of these devices, quantization offers a promising solution by improving memory efficiency and reducing bandwidth requirements, thereby facilitating the deployment of VLMs. However, existing research has rarely explored aggressive quantization on VLMs, particularly for the models ranging from 1B to 2B parameters, which are more suitable for resource-constrained edge devices. In this paper, we propose SPEED-Q, a novel Staged Processing with Enhanced Distillation framework for VLM low-bit weight-only quantization that systematically addresses the following two critical obstacles: (1) significant discrepancies in quantization sensitivity between vision (ViT) and language (LLM) components in VLMs; (2) training instability arising from the reduced numerical precision inherent in low-bit quantization. In SPEED-Q, a staged sensitivity adaptive mechanism is introduced to effectively harmonize performance across different modalities. We further propose a distillation-enhanced quantization strategy to stabilize the training process and reduce data dependence. Together, SPEED-Q enables accurate, stable, and data-efficient quantization of complex VLMs. SPEED-Q is the first framework tailored for quantizing entire small-scale billion-parameter VLMs to low bits. Extensive experiments across multiple benchmarks demonstrate that SPEED-Q achieves up to 6x higher accuracy than existing quantization methods under 2-bit settings and consistently outperforms prior on-device VLMs under both 2-bit and 4-bit settings. Our code and models are available at https://github.com/antgroup/SPEED-Q.
DeepDR: an integrated deep-learning model web server for drug repositioning
Venue: arXiv cs.LG 2025
Year: 2025

Background: Identifying new indications for approved drugs is a complex and time-consuming process that requires extensive knowledge of pharmacology, clinical data, and advanced computational methods. Recently, deep learning (DL) methods have shown their capability for the accurate prediction of drug repositioning. However, implementing DL-based modeling requires in-depth domain knowledge and proficient programming skills. Results: In this application, we introduce DeepDR, the first integrated platform that combines a variety of established DL-based models for disease- and target-specific drug repositioning tasks. DeepDR leverages invaluable experience to recommend candidate drugs, which covers more than 15 networks and a comprehensive knowledge graph that includes 5.9 million edges across 107 types of relationships connecting drugs, diseases, proteins/genes, pathways, and expression from six existing databases and a large scientific corpus of 24 million PubMed publications. Additionally, the recommended results include detailed descriptions of the recommended drugs and visualize key patterns with interpretability through a knowledge graph. Conclusion: DeepDR is free and open to all users without the requirement of registration. We believe it can provide an easy-to-use, systematic, highly accurate, and computationally automated platform for both experimental and computational scientists.
Expand Your SCOPE: Semantic Cognition over Potential-Based Exploration for Embodied Visual Navigation
Venue: arXiv cs.RO 2025
Year: 2025

Embodied visual navigation remains a challenging task, as agents must explore unknown environments with limited knowledge. Existing zero-shot studies have shown that incorporating memory mechanisms to support goal-directed behavior can improve long-horizon planning performance. However, they overlook visual frontier boundaries, which fundamentally dictate future trajectories and observations, and fall short of inferring the relationship between partial visual observations and navigation goals. In this paper, we propose Semantic Cognition Over Potential-based Exploration (SCOPE), a zero-shot framework that explicitly leverages frontier information to drive potential-based exploration, enabling more informed and goal-relevant decisions. SCOPE estimates exploration potential with a Vision-Language Model and organizes it into a spatio-temporal potential graph, capturing boundary dynamics to support long-horizon planning. In addition, SCOPE incorporates a self-reconsideration mechanism that revisits and refines prior decisions, enhancing reliability and reducing overconfident errors. Experimental results on two diverse embodied navigation tasks show that SCOPE outperforms state-of-the-art baselines by 4.6\% in accuracy. Further analysis demonstrates that its core components lead to improved calibration, stronger generalization, and higher decision quality.
AuthSig: Safeguarding Scanned Signatures Against Unauthorized Reuse in Paperless Workflows
Venue: arXiv cs.CV 2025
Year: 2025

With the deepening trend of paperless workflows, signatures as a means of identity authentication are gradually shifting from traditional ink-on-paper to electronic formats.Despite the availability of dynamic pressure-sensitive and PKI-based digital signatures, static scanned signatures remain prevalent in practice due to their convenience. However, these static images, having almost lost their authentication attributes, cannot be reliably verified and are vulnerable to malicious copying and reuse. To address these issues, we propose AuthSig, a novel static electronic signature framework based on generative models and watermark, which binds authentication information to the signature image. Leveraging the human visual system's insensitivity to subtle style variations, AuthSig finely modulates style embeddings during generation to implicitly encode watermark bits-enforcing a One Signature, One Use policy.To overcome the scarcity of handwritten signature data and the limitations of traditional augmentation methods, we introduce a keypoint-driven data augmentation strategy that effectively enhances style diversity to support robust watermark embedding. Experimental results show that AuthSig achieves over 98% extraction accuracy under both digital-domain distortions and signature-specific degradations, and remains effective even in print-scan scenarios.
Efficient and Effective In-context Demonstration Selection with Coreset
Venue: arXiv cs.CV 2025
Year: 2025

In-context learning (ICL) has emerged as a powerful paradigm for Large Visual Language Models (LVLMs), enabling them to leverage a few examples directly from input contexts. However, the effectiveness of this approach is heavily reliant on the selection of demonstrations, a process that is NP-hard. Traditional strategies, including random, similarity-based sampling and infoscore-based sampling, often lead to inefficiencies or suboptimal performance, struggling to balance both efficiency and effectiveness in demonstration selection. In this paper, we propose a novel demonstration selection framework named Coreset-based Dual Retrieval (CoDR). We show that samples within a diverse subset achieve a higher expected mutual information. To implement this, we introduce a cluster-pruning method to construct a diverse coreset that aligns more effectively with the query while maintaining diversity. Additionally, we develop a dual retrieval mechanism that enhances the selection process by achieving global demonstration selection while preserving efficiency. Experimental results demonstrate that our method significantly improves the ICL performance compared to the existing strategies, providing a robust solution for effective and efficient demonstration selection.
Data reuse enables cost-efficient randomized trials of medical AI models
Venue: arXiv cs.LG 2025
Year: 2025

Randomized controlled trials (RCTs) are indispensable for establishing the clinical value of medical artificial-intelligence (AI) tools, yet their high cost and long timelines hinder timely validation as new models emerge rapidly. Here, we propose BRIDGE, a data-reuse RCT design for AI-based risk models. AI risk models support a broad range of interventions, including screening, treatment selection, and clinical alerts. BRIDGE trials recycle participant-level data from completed trials of AI models when legacy and updated models make concordant predictions, thereby reducing the enrollment requirement for subsequent trials. We provide a practical checklist for investigators to assess whether reusing data from previous trials allows for valid causal inference and preserves type I error. Using real-world datasets across breast cancer, cardiovascular disease, and sepsis, we demonstrate concordance between successive AI models, with up to 64.8% overlap in top 5% high-risk cohorts. We then simulate a series of breast cancer screening studies, where our design reduced required enrollment by 46.6%--saving over US$2.8 million--while maintaining 80% power. By transforming trials into adaptive, modular studies, our proposed design makes Level I evidence generation feasible for every model iteration, thereby accelerating cost-effective translation of AI into routine care.
Solving a Million-Step LLM Task with Zero Errors
Venue: arXiv cs.AI 2025
Year: 2025

LLMs have achieved remarkable breakthroughs in reasoning, insights, and tool use, but chaining these abilities into extended processes at the scale of those routinely executed by humans, organizations, and societies has remained out of reach. The models have a persistent error rate that prevents scale-up: for instance, recent experiments in the Towers of Hanoi benchmark domain showed that the process inevitably becomes derailed after at most a few hundred steps. Thus, although LLM research is often still benchmarked on tasks with relatively few dependent logical steps, there is increasing attention on the ability (or inability) of LLMs to perform long range tasks. This paper describes MAKER, the first system that successfully solves a task with over one million LLM steps with zero errors, and, in principle, scales far beyond this level. The approach relies on an extreme decomposition of a task into subtasks, each of which can be tackled by focused microagents. The high level of modularity resulting from the decomposition allows error correction to be applied at each step through an efficient multi-agent voting scheme. This combination of extreme decomposition and error correction makes scaling possible. Thus, the results suggest that instead of relying on continual improvement of current LLMs, massively decomposed agentic processes (MDAPs) may provide a way to efficiently solve problems at the level of organizations and societies.
Argus: Resilience-Oriented Safety Assurance Framework for End-to-End ADSs
Venue: arXiv cs.AI 2025
Year: 2025

End-to-end autonomous driving systems (ADSs), with their strong capabilities in environmental perception and generalizable driving decisions, are attracting growing attention from both academia and industry. However, once deployed on public roads, ADSs are inevitably exposed to diverse driving hazards that may compromise safety and degrade system performance. This raises a strong demand for resilience of ADSs, particularly the capability to continuously monitor driving hazards and adaptively respond to potential safety violations, which is crucial for maintaining robust driving behaviors in complex driving scenarios. To bridge this gap, we propose a runtime resilience-oriented framework, Argus, to mitigate the driving hazards, thus preventing potential safety violations and improving the driving performance of an ADS. Argus continuously monitors the trajectories generated by the ADS for potential hazards and, whenever the EGO vehicle is deemed unsafe, seamlessly takes control through a hazard mitigator. We integrate Argus with three state-of-the-art end-to-end ADSs, i.e., TCP, UniAD and VAD. Our evaluation has demonstrated that Argus effectively and efficiently enhances the resilience of ADSs, improving the driving score of the ADS by up to 150.30% on average, and preventing up to 64.38% of the violations, with little additional time overhead.
Diversifying Counterattacks: Orthogonal Exploration for Robust CLIP Inference
Venue: arXiv cs.CV 2025
Year: 2025

Vision-language pre-training models (VLPs) demonstrate strong multimodal understanding and zero-shot generalization, yet remain vulnerable to adversarial examples, raising concerns about their reliability. Recent work, Test-Time Counterattack (TTC), improves robustness by generating perturbations that maximize the embedding deviation of adversarial inputs using PGD, pushing them away from their adversarial representations. However, due to the fundamental difference in optimization objectives between adversarial attacks and counterattacks, generating counterattacks solely based on gradients with respect to the adversarial input confines the search to a narrow space. As a result, the counterattacks could overfit limited adversarial patterns and lack the diversity to fully neutralize a broad range of perturbations. In this work, we argue that enhancing the diversity and coverage of counterattacks is crucial to improving adversarial robustness in test-time defense. Accordingly, we propose Directional Orthogonal Counterattack (DOC), which augments counterattack optimization by incorporating orthogonal gradient directions and momentum-based updates. This design expands the exploration of the counterattack space and increases the diversity of perturbations, which facilitates the discovery of more generalizable counterattacks and ultimately improves the ability to neutralize adversarial perturbations. Meanwhile, we present a directional sensitivity score based on averaged cosine similarity to boost DOC by improving example discrimination and adaptively modulating the counterattack strength. Extensive experiments on 16 datasets demonstrate that DOC improves adversarial robustness under various attacks while maintaining competitive clean accuracy. Code is available at https://github.com/bookman233/DOC.
Composition-Incremental Learning for Compositional Generalization
Venue: arXiv cs.CV 2025
Year: 2025

Compositional generalization has achieved substantial progress in computer vision on pre-collected training data. Nonetheless, real-world data continually emerges, with possible compositions being nearly infinite, long-tailed, and not entirely visible. Thus, an ideal model is supposed to gradually improve the capability of compositional generalization in an incremental manner. In this paper, we explore Composition-Incremental Learning for Compositional Generalization (CompIL) in the context of the compositional zero-shot learning (CZSL) task, where models need to continually learn new compositions, intending to improve their compositional generalization capability progressively. To quantitatively evaluate CompIL, we develop a benchmark construction pipeline leveraging existing datasets, yielding MIT-States-CompIL and C-GQA-CompIL. Furthermore, we propose a pseudo-replay framework utilizing a visual synthesizer to synthesize visual representations of learned compositions and a linguistic primitive distillation mechanism to maintain aligned primitive representations across the learning process. Extensive experiments demonstrate the effectiveness of the proposed framework.