OpenRaiser/Intern-Atlas huggingface dataset:
Multimodal Protein Language Models for Enzyme Kinetic Parameters: From Substrate Recognition to Conformational Adaptation
Venue: arXiv cs.CV 2026
Year: 2026

Predicting enzyme kinetic parameters quantifies how efficiently an enzyme catalyzes a specific substrate under defined biochemical conditions. Canonical parameters such as the turnover number ($k_\text{cat}$), Michaelis constant ($K_\text{m}$), and inhibition constant ($K_\text{i}$) depend jointly on the enzyme sequence, the substrate chemistry, and the conformational adaptation of the active site during binding. Many learning pipelines simplify this process to a static compatibility problem between the enzyme and substrate, fusing their representations through shallow operations and regressing a single value. Such formulations overlook the staged nature of catalysis, which involves both substrate recognition and conformational adaptation. In this regard, we reformulate kinetic prediction as a staged multimodal conditional modeling problem and introduce the Enzyme-Reaction Bridging Adapter (ERBA), which injects cross-modal information via fine-tuning into Protein Language Models (PLMs) while preserving their biochemical priors. ERBA performs conditioning in two stages: Molecular Recognition Cross-Attention (MRCA) first injects substrate information into the enzyme representation to capture specificity; Geometry-aware Mixture-of-Experts (G-MoE) then integrates active-site structure and routes samples to pocket-specialized experts to reflect induced fit. To maintain semantic fidelity, Enzyme-Substrate Distribution Alignment (ESDA) enforces distributional consistency within the PLM manifold in a reproducing kernel Hilbert space. Experiments across three kinetic endpoints and multiple PLM backbones, ERBA delivers consistent gains and stronger out-of-distribution performance compared with sequence-only and shallow-fusion baselines, offering a biologically grounded route to scalable kinetic prediction and a foundation for adding cofactors, mutations, and time-resolved structural cues.
Beyond Imitation: Reinforcement Learning Fine-Tuning for Adaptive Diffusion Navigation Policies
Venue: arXiv cs.RO 2026
Year: 2026

Diffusion-based robot navigation policies trained on large-scale imitation learning datasets, can generate multi-modal trajectories directly from the robot's visual observations, bypassing the traditional localization-mapping-planning pipeline and achieving strong zero-shot generalization. However, their performance remains constrained by the coverage of offline datasets, and when deployed in unseen settings, distribution shift often leads to accumulated trajectory errors and safety-critical failures. Adapting diffusion policies with reinforcement learning is challenging because their iterative denoising structure hinders effective gradient backpropagation, while also making the training of an additional value network computationally expensive and less stable. To address these issues, we propose a reinforcement learning fine-tuning framework tailored for diffusion-based navigation. The method leverages the inherent multi-trajectory sampling mechanism of diffusion models and adopts Group Relative Policy Optimization (GRPO), which estimates relative advantages across sampled trajectories without requiring a separate value network. To preserve pretrained representations while enabling adaptation, we freeze the visual encoder and selectively update the higher decoder layers and action head, enhancing safety-aware behaviors through online environmental feedback. On the PointGoal task in Isaac Sim, our approach improves the Success Rate from 52.0% to 58.7% and SPL from 0.49 to 0.54 on unseen scenes, while reducing collision frequency. Additional experiments show that the fine-tuned policy transfers zero-shot to a real quadruped platform and maintains stable performance in geometrically out-of-distribution environments, suggesting improved adaptability and safe generalization to new domains.
TRACE: Structure-Aware Character Encoding for Robust and Generalizable Document Watermarking
Venue: arXiv cs.CV 2026
Year: 2026

We propose TRACE, a structure-aware framework leveraging diffusion models for localized character encoding to embed data. Unlike existing methods that rely on edge features or pre-defined codebooks, TRACE exploits character structures that provide inherent resistance to noise interference due to their stability and unified representation across diverse characters. Our framework comprises three key components: (1) adaptive diffusion initialization that automatically identifies handle points, target points, and editing regions through specialized algorithms including movement probability estimator (MPE), target point estimation (TPE) and mask drawing model (MDM), (2) guided diffusion encoding for precise movement of selected point, and (3) masked region replacement with a specialized loss function to minimize feature alterations after the diffusion process. Comprehensive experiments demonstrate \name{}'s superior performance over state-of-the-art methods, achieving more than 5 dB improvement in PSNR and 5\% higher extraction accuracy following cross-media transmission. \name{} achieves broad generalizability across multiple languages and fonts, making it particularly suitable for practical document security applications.
Enhanced Drug-drug Interaction Prediction Using Adaptive Knowledge Integration
Venue: arXiv cs.LG 2026
Year: 2026

Drug-drug interaction event (DDIE) prediction is crucial for preventing adverse reactions and ensuring optimal therapeutic outcomes. However, existing methods often face challenges with imbalanced datasets, complex interaction mechanisms, and poor generalization to unknown drug combinations. To address these challenges, we propose a knowledge augmentation framework that adaptively infuses prior drug knowledge into a large language model (LLM). This framework utilizes reinforcement learning techniques to facilitate adaptive knowledge extraction and synthesis, thereby efficiently optimizing the strategy space to enhance the accuracy of LLMs for DDIE predictions. As a result of few-shot learning, we achieved a notable improvement compared to the baseline. This approach establishes an effective framework for scientific knowledge learning for DDIE predictions.
A Physics-Based Digital Human Twin for Galvanic-Coupling Wearable Communication Links
Venue: arXiv cs.ET 2026
Year: 2026

This paper presents a systematic characterization of wearable galvanic coupling (GC) channels under narrowband and wideband operation. A physics-consistent digital human twin maps anatomical properties, propagation geometry, and electrode-skin interfaces into complex transfer functions directly usable for communication analysis. Attenuation, phase delay, and group delay are evaluated for longitudinal and radial configurations, and dispersion-induced variability is quantified through attenuation ripple and delay standard deviation metrics versus bandwidth. Results confirm electro-quasistatic, weakly dispersive behavior over 10 kHz-1 MHz. Attenuation is primarily geometry-driven, whereas amplitude ripple and delay variability increase with bandwidth, tightening equalization and synchronization constraints. Interface conditioning (gel and foam) significantly improves amplitude and phase stability, while propagation geometry governs link budget and baseline delay. Overall, the framework quantitatively links tissue electromagnetics to waveform distortion, enabling informed trade-offs among bandwidth, interface design, and transceiver complexity in wearable GC systems.
Spectral-Geometric Neural Fields for Pose-Free LiDAR View Synthesis
Venue: arXiv cs.CV 2026
Year: 2026

Neural Radiance Fields (NeRF) have shown remarkable success in image novel view synthesis (NVS), inspiring extensions to LiDAR NVS. However, most methods heavily rely on accurate camera poses for scene reconstruction. The sparsity and textureless nature of LiDAR data also present distinct challenges, leading to geometric holes and discontinuous surfaces. To address these issues, we propose SG-NLF, a pose-free LiDAR NeRF framework that integrates spectral information with geometric consistency. Specifically, we design a hybrid representation based on spectral priors to reconstruct smooth geometry. For pose optimization, we construct a confidence-aware graph based on feature compatibility to achieve global alignment. In addition, an adversarial learning strategy is introduced to enforce cross-frame consistency, thereby enhancing reconstruction quality. Comprehensive experiments demonstrate the effectiveness of our framework, especially in challenging low-frequency scenarios. Compared to previous state-of-the-art methods, SG-NLF improves reconstruction quality and pose accuracy by over 35.8% and 68.8%. Our work can provide a novel perspective for LiDAR view synthesis.
Learning from Child-Directed Speech in Two-Language Scenarios: A French-English Case Study
Venue: arXiv cs.CL 2026
Year: 2026

Research on developmentally plausible language models has largely focused on English, leaving open questions about multilingual settings. We present a systematic study of compact language models by extending BabyBERTa to English-French scenarios under strictly size-matched data conditions, covering monolingual, bilingual, and cross-lingual settings. Our design contrasts two types of training corpora: (i) child-directed speech (about 2.5M tokens), following BabyBERTa and related work, and (ii) multi-domain corpora (about 10M tokens), extending the BabyLM framework to French. To enable fair evaluation, we also introduce new resources, including French versions of QAMR and QASRL, as well as English and French multi-domain corpora. We evaluate the models on both syntactic and semantic tasks and compare them with models trained on Wikipedia-only data. The results reveal context-dependent effects: training on Wikipedia consistently benefits semantic tasks, whereas child-directed speech improves grammatical judgments in monolingual settings. Bilingual pretraining yields notable gains for textual entailment, with particularly strong improvements for French. Importantly, similar patterns emerge across BabyBERTa, RoBERTa, and LTG-BERT, suggesting consistent trends across architectures.
Surprised by Attention: Predictable Query Dynamics for Time Series Anomaly Detection
Venue: arXiv cs.LG 2026
Year: 2026

Multivariate time series anomalies often manifest as shifts in cross-channel dependencies rather than simple amplitude excursions. In autonomous driving, for instance, a steering command might be internally consistent but decouple from the resulting lateral acceleration. Residual-based detectors can miss such anomalies when flexible sequence models still reconstruct signals plausibly despite altered coordination. We introduce AxonAD, an unsupervised detector that treats multi-head attention query evolution as a short horizon predictable process. A gradient-updated reconstruction pathway is coupled with a history-only predictor that forecasts future query vectors from past context. This is trained via a masked predictor-target objective against an exponential moving average (EMA) target encoder. At inference, reconstruction error is combined with a tail-aggregated query mismatch score, which measures cosine deviation between predicted and target queries on recent timesteps. This dual approach provides sensitivity to structural dependency shifts while retaining amplitude-level detection. On proprietary in-vehicle telemetry with interval annotations and on the TSB-AD multi-variate suite (17 datasets, 180 series) with threshold-free and range-aware metrics, AxonAD improves ranking quality and temporal localization over strong baselines. Ablations confirm that query prediction and combined scoring are the primary drivers of the observed gains. Code is available at the URL https://github.com/iis-esslingen/AxonAD.
Teaching Agile Requirements Engineering: A Stakeholder Simulation with Generative AI
Venue: arXiv cs.SE 2026
Year: 2026

Context: The active involvement of users and customers in agile software development remains a persistent challenge in practice. For this reason, it is important that students in higher education become familiar with good practices in Agile Requirements Engineering during their studies. Objective: Our objective is to enable students to learn how to interact with Generative Artificial Intelligence (GenAI) through the use of a stakeholder simulation with AI Personas, while also developing an understanding of the limitations of AI tools in practical contexts. Method: In our courses, we employ a stakeholder simulation using GenAI, in which students conduct interviews with AI Personas through a provided meta-prompt. Based on the outcomes of these interviews, students apply agile practices (e.g., story mapping or impact mapping) to document requirements. The use of GenAI is subsequently reflected upon in a structured group discussion. Results: Through this approach, students gain practical experience by applying state-of-the art agile practices for requirements elicitation and documentation while simultaneously developing an understanding of the technical and ethical limitations associated with the use of generative AI. Conclusion: We have applied this approach over several terms and found that using a meta-prompt provides flexibility, allowing us to remain independent of specific large language model providers.
ODRL Policy Comparison Through Normalisation
Venue: arXiv cs.AI 2026
Year: 2026

The ODRL language has become the standard for representing policies and regulations for digital rights. However its complexity is a barrier to its usage, which has caused many related theoretical and practical works to focus on different, and not interoperable, fragments of ODRL. Moreover, semantically equivalent policies can be expressed in numerous different ways, which makes comparing them and processing them harder. Building on top of a recently defined semantics, we tackle these problems by proposing an approach that involves a parametrised normalisation of ODRL policies into its minimal components which reformulates policies with permissions and prohibitions into policies with permissions exclusively, and simplifies complex logic constraints into simple ones. We provide algorithms to compute a normal form for ODRL policies and simplifying numerical and symbolic constraints. We prove that these algorithms preserve the semantics of policies, and analyse the size complexity of the result, which is exponential on the number of attributes and linear on the number of unique values for these attributes. We show how this makes complex policies representable in more basic fragments of ODRL, and how it reduces the problem of policy comparison to the simpler problem of checking if two rules are identical.
DS$^2$-Instruct: Domain-Specific Data Synthesis for Large Language Models Instruction Tuning
Venue: arXiv cs.CL 2026
Year: 2026

Adapting Large Language Models (LLMs) to specialized domains requires high-quality instruction tuning datasets, which are expensive to create through human annotation. Existing data synthesis methods focus on general-purpose tasks and fail to capture domain-specific terminology and reasoning patterns. To address this, we introduce DS$^2$-Instruct, a zero-shot framework that generates domain-specific instruction datasets without human supervision. Our approach first generates task-informed keywords to ensure comprehensive domain coverage. It then creates diverse instructions by pairing these keywords with different cognitive levels from Bloom's Taxonomy. Finally, it uses self-consistency validation to ensure data quality. We apply this framework to generate datasets across seven challenging domains, such as mathematics, finance, and logical reasoning. Comprehensive evaluation demonstrates that models fine-tuned on our generated data achieve substantial improvements over existing data generation methods.
SGMatch: Semantic-Guided Non-Rigid Shape Matching with Flow Regularization
Venue: arXiv cs.CV 2026
Year: 2026

Establishing accurate point-to-point correspondences between non-rigid 3D shapes remains a critical challenge, particularly under non-isometric deformations and topological noise. Existing functional map pipelines suffer from ambiguities that geometric descriptors alone cannot resolve, and spatial inconsistencies inherent in the projection of truncated spectral bases to dense pointwise correspondences. In this paper, we introduce SGMatch, a learning-based framework for semantic-guided non-rigid shape matching. Specifically, we design a Semantic-Guided Local Cross-Attention module that integrates semantic features from vision foundation models into geometric descriptors while preserving local structural continuity. Furthermore, we introduce a regularization objective based on conditional flow matching, which supervises a time-varying velocity field to encourage spatial smoothness of the recovered correspondences. Experimental results on multiple benchmarks demonstrate that SGMatch achieves competitive performance across near-isometric settings and consistent improvements under non-isometric deformations and topological noise.
Thinking in Streaming Video
Venue: arXiv cs.CV 2026
Year: 2026

Real-time understanding of continuous video streams is essential for interactive assistants and multimodal agents operating in dynamic environments. However, most existing video reasoning approaches follow a batch paradigm that defers reasoning until the full video context is observed, resulting in high latency and growing computational cost that are incompatible with streaming scenarios. In this paper, we introduce ThinkStream, a framework for streaming video reasoning based on a Watch--Think--Speak paradigm that enables models to incrementally update their understanding as new video observations arrive. At each step, the model performs a short reasoning update and decides whether sufficient evidence has accumulated to produce a response. To support long-horizon streaming, we propose Reasoning-Compressed Streaming Memory (RCSM), which treats intermediate reasoning traces as compact semantic memory that replaces outdated visual tokens while preserving essential context. We further train the model using a Streaming Reinforcement Learning with Verifiable Rewards scheme that aligns incremental reasoning and response timing with the requirements of streaming interaction. Experiments on multiple streaming video benchmarks show that ThinkStream significantly outperforms existing online video models while maintaining low latency and memory usage. Code, models and data will be released at https://github.com/johncaged/ThinkStream
ReMem-VLA: Empowering Vision-Language-Action Model with Memory via Dual-Level Recurrent Queries
Venue: arXiv cs.RO 2026
Year: 2026

Vision-language-action (VLA) models for closed-loop robot control are typically cast under the Markov assumption, making them prone to errors on tasks requiring historical context. To incorporate memory, existing VLAs either retrieve from a memory bank, which can be misled by distractors, or extend the frame window, whose fixed horizon still limits long-term retention. In this paper, we introduce ReMem-VLA, a Recurrent Memory VLA model equipped with two sets of learnable queries: frame-level recurrent memory queries for propagating information across consecutive frames to support short-term memory, and chunk-level recurrent memory queries for carrying context across temporal chunks for long-term memory. These queries are trained end-to-end to aggregate and maintain relevant context over time, implicitly guiding the model's decisions without additional training or inference cost. Furthermore, to enhance visual memory, we introduce Past Observation Prediction as an auxiliary training objective. Through extensive memory-centric simulation and real-world robot experiments, we demonstrate that ReMem-VLA exhibits strong memory capabilities across multiple dimensions, including spatial, sequential, episodic, temporal, and visual memory. ReMem-VLA significantly outperforms memory-free VLA baselines $π$0.5 and OpenVLA-OFT and surpasses MemoryVLA on memory-dependent tasks by a large margin.
Long-form RewardBench: Evaluating Reward Models for Long-form Generation
Venue: arXiv cs.CL 2026
Year: 2026

The widespread adoption of reinforcement learning-based alignment highlights the growing importance of reward models. Various benchmarks have been built to evaluate reward models in various domains and scenarios. However, a significant gap remains in assessing reward models for long-form generation, despite its critical role in real-world applications. To bridge this, we introduce Long-form RewardBench, the first reward modeling testbed specifically designed for long-form generation. Our benchmark encompasses five key subtasks: QA, RAG, Chat, Writing, and Reasoning. We collected instruction and preference data through a meticulously designed multi-stage data collection process, and conducted extensive experiments on 20+ mainstream reward models, including both classifiers and generative models. Our findings reveal that current models still lack long-form reward modeling capabilities. Furthermore, we designed a novel Long-form Needle-in-a-Haystack Test, which revealed a correlation between reward modeling performance and the error's position within a response, as well as the overall response length, with distinct characteristics observed between classification and generative models. Finally, we demonstrate that classifiers exhibit better generalizability compared to generative models trained on the same data. As the first benchmark for long-form reward modeling, this work aims to offer a robust platform for visualizing progress in this crucial area.
SCOPE: Semantic Coreset with Orthogonal Projection Embeddings for Federated learning
Venue: arXiv cs.LG 2026
Year: 2026

Scientific discovery increasingly requires learning on federated datasets, fed by streams from high-resolution instruments, that have extreme class imbalance. Current ML approaches either require impractical data aggregation or fail due to class imbalance. Existing coreset selection methods rely on local heuristics, making them unaware of the global data landscape and prone to sub-optimal and non-representative pruning. To overcome these challenges, we introduce SCOPE (Semantic Coreset using Orthogonal Projection Embeddings for Federated learning), a coreset framework for federated data that filters anomalies and adaptively prunes redundant data to mitigate long-tail skew. By analyzing the latent space distribution, we score each data point using a representation score that measures the reliability of core class features, a diversity score that quantifies the novelty of orthogonal residuals, and a boundary proximity score that indicates similarity to competing classes. Unlike prior methods, SCOPE shares only scalar metrics with a federated server to construct a global consensus, ensuring communication efficiency. Guided by the global consensus, SCOPE dynamically filters local noise and discards redundant samples to counteract global feature skews. Extensive experiments demonstrate that SCOPE yields competitive global accuracy and robust convergence, all while achieving exceptional efficiency with a 128x to 512x reduction in uplink bandwidth, a 7.72x wall-clock acceleration and reduced FLOP and VRAM footprints for local coreset selection.